# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RecO_C PF02565.15 CDJ61976.1 - 0.0051 16.6 0.2 0.015 15.1 0.2 1.8 1 0 0 1 1 1 1 Recombination protein O C terminal Suf PF05843.14 CDJ61976.1 - 0.0052 16.8 0.0 0.73 9.8 0.0 2.3 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) Tic110 PF16940.5 CDJ61976.1 - 1.3 7.4 4.6 0.89 8.0 0.5 2.2 2 0 0 2 2 2 0 Chloroplast envelope transporter Kri1_C PF12936.7 CDJ61977.1 - 9.8e-25 86.6 1.5 9.8e-25 86.6 1.5 5.0 5 1 1 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.12 CDJ61977.1 - 1.4e-15 57.7 9.9 1.4e-15 57.7 9.9 5.5 3 2 1 4 4 4 1 KRI1-like family ZZ PF00569.17 CDJ61977.1 - 2.4e-07 30.5 3.0 8.2e-07 28.7 3.1 1.9 2 0 0 2 2 2 1 Zinc finger, ZZ type RskA PF10099.9 CDJ61977.1 - 0.0021 18.4 24.6 0.13 12.5 17.0 2.8 2 1 0 2 2 2 2 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ61977.1 - 0.12 12.0 87.5 0.01 15.5 28.1 4.8 5 1 0 5 5 5 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ61978.1 - 9.3e-05 22.6 28.8 0.00011 22.4 28.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TMEM51 PF15345.6 CDJ61978.1 - 0.00091 19.1 12.3 0.0012 18.8 12.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 MMR1 PF08505.10 CDJ61978.1 - 0.0015 18.9 17.8 0.0016 18.8 17.8 1.1 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein Spt20 PF12090.8 CDJ61978.1 - 0.0042 16.7 43.0 0.0053 16.4 43.0 1.1 1 0 0 1 1 1 1 Spt20 family Apt1 PF10351.9 CDJ61978.1 - 0.015 14.2 14.8 0.014 14.3 14.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tim54 PF11711.8 CDJ61978.1 - 0.018 13.8 8.1 0.018 13.8 8.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SPX PF03105.19 CDJ61978.1 - 0.027 14.4 16.1 0.029 14.3 16.1 1.1 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 CDJ61978.1 - 0.036 12.8 20.2 0.044 12.5 20.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NPR3 PF03666.13 CDJ61978.1 - 0.059 12.2 12.7 0.066 12.0 12.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 CDJ61978.1 - 0.061 11.9 20.4 0.067 11.8 20.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 CDJ61978.1 - 0.062 12.6 16.1 0.091 12.1 16.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDJ61978.1 - 0.065 12.0 20.3 0.072 11.8 20.3 1.1 1 0 0 1 1 1 0 Presenilin DUF702 PF05142.12 CDJ61978.1 - 0.072 13.6 14.7 0.1 13.1 14.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) GREB1 PF15782.5 CDJ61978.1 - 0.09 9.9 21.4 0.092 9.9 21.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RLL PF10036.9 CDJ61978.1 - 0.11 12.3 11.7 0.16 11.8 11.7 1.3 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein AF-4 PF05110.13 CDJ61978.1 - 0.12 10.4 29.0 0.16 10.0 29.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SSP160 PF06933.11 CDJ61978.1 - 0.12 10.5 19.3 0.2 9.8 19.3 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Draxin PF15550.6 CDJ61978.1 - 0.17 11.7 14.8 0.22 11.4 14.8 1.1 1 0 0 1 1 1 0 Draxin WTX PF09422.10 CDJ61978.1 - 0.19 10.8 16.4 0.21 10.6 16.4 1.0 1 0 0 1 1 1 0 WTX protein Sec62 PF03839.16 CDJ61978.1 - 0.2 11.2 7.8 0.25 10.8 7.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 MPM1 PF17234.2 CDJ61978.1 - 0.21 11.8 19.1 0.3 11.3 19.1 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 FAM76 PF16046.5 CDJ61978.1 - 0.35 10.2 21.3 0.54 9.6 21.3 1.3 1 0 0 1 1 1 0 FAM76 protein FAM176 PF14851.6 CDJ61978.1 - 0.56 9.9 9.6 0.83 9.3 9.6 1.4 1 0 0 1 1 1 0 FAM176 family PAP1 PF08601.10 CDJ61978.1 - 0.58 9.8 26.1 0.66 9.6 26.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 CDK2AP PF09806.9 CDJ61978.1 - 0.67 10.0 29.6 1 9.4 29.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Med24_N PF11277.8 CDJ61978.1 - 0.73 7.8 10.4 0.67 7.9 10.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF572 PF04502.13 CDJ61978.1 - 0.82 9.2 16.9 0.93 9.1 16.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) TERB2 PF15101.6 CDJ61978.1 - 0.9 9.6 22.4 1.3 9.0 22.4 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Lin-8 PF03353.15 CDJ61978.1 - 1.1 8.8 26.4 1.3 8.5 26.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Rrn6 PF10214.9 CDJ61978.1 - 1.2 7.5 23.2 1.3 7.4 23.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peroxin-3 PF04882.12 CDJ61978.1 - 1.3 7.9 19.2 1.4 7.8 19.2 1.2 1 0 0 1 1 1 0 Peroxin-3 Otopetrin PF03189.13 CDJ61978.1 - 1.6 7.5 10.8 1.8 7.3 10.8 1.2 1 0 0 1 1 1 0 Otopetrin SOG2 PF10428.9 CDJ61978.1 - 1.6 7.8 33.8 2.1 7.4 33.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Roughex PF06020.11 CDJ61978.1 - 1.8 7.6 17.6 2.8 7.0 17.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF4770 PF15994.5 CDJ61978.1 - 1.8 8.8 13.8 2.3 8.4 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FCP1_C PF09309.10 CDJ61978.1 - 1.9 8.3 17.0 2.8 7.8 17.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal NST1 PF13945.6 CDJ61978.1 - 2.2 8.3 27.5 3 7.9 27.5 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Band_3_cyto PF07565.13 CDJ61978.1 - 2.4 7.9 17.8 3.2 7.5 17.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4647 PF15504.6 CDJ61978.1 - 2.6 7.1 20.0 3.2 6.7 20.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF4746 PF15928.5 CDJ61978.1 - 2.8 7.3 12.7 3.2 7.1 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AUX_IAA PF02309.16 CDJ61978.1 - 2.9 7.7 13.2 3.6 7.4 13.2 1.2 1 0 0 1 1 1 0 AUX/IAA family SLC12 PF03522.15 CDJ61978.1 - 3.3 6.6 21.2 3.9 6.4 21.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Adeno_PV PF03910.13 CDJ61978.1 - 3.6 6.2 14.0 6.1 5.4 14.0 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV Connexin PF00029.19 CDJ61978.1 - 3.7 7.2 11.8 4.7 6.9 11.8 1.2 1 0 0 1 1 1 0 Connexin DUF3292 PF11696.8 CDJ61978.1 - 4.2 5.6 12.1 5.1 5.3 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) BAF1_ABF1 PF04684.13 CDJ61978.1 - 4.2 6.3 23.3 5.3 6.0 23.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SpoIIP PF07454.11 CDJ61978.1 - 4.3 6.7 18.3 5.4 6.4 18.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PAT1 PF09770.9 CDJ61978.1 - 4.6 5.4 28.8 5.3 5.2 28.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ61978.1 - 4.7 5.4 14.9 5 5.3 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.11 CDJ61978.1 - 5.3 6.3 16.6 6.3 6.1 16.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF913 PF06025.12 CDJ61978.1 - 6.3 5.7 13.8 7.7 5.4 13.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SRP-alpha_N PF04086.13 CDJ61978.1 - 6.7 6.5 23.8 8.5 6.2 23.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Gti1_Pac2 PF09729.9 CDJ61978.1 - 7.3 6.6 18.9 11 6.1 18.9 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family EF1_GNE PF00736.19 CDJ61979.1 - 4.3e-33 113.4 3.8 4.3e-33 113.4 3.8 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain Flavin_Reduct PF01613.18 CDJ61979.1 - 0.11 12.5 0.1 0.42 10.6 0.1 1.8 1 1 0 1 1 1 0 Flavin reductase like domain SUIM_assoc PF16619.5 CDJ61979.1 - 0.13 12.3 8.8 0.26 11.4 8.8 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF1840 PF08895.11 CDJ61979.1 - 0.8 10.1 7.4 1.1 9.6 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) UBA2_C PF16195.5 CDJ61979.1 - 0.86 10.3 9.4 0.49 11.1 4.5 2.2 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Rsc14 PF08586.10 CDJ61979.1 - 2.4 9.0 7.3 0.59 11.0 1.8 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Androgen_recep PF02166.16 CDJ61979.1 - 4.5 6.0 7.9 5.8 5.6 7.9 1.1 1 0 0 1 1 1 0 Androgen receptor Hamartin PF04388.12 CDJ61981.1 - 0.051 12.3 9.8 0.063 11.9 9.8 1.0 1 0 0 1 1 1 0 Hamartin protein Presenilin PF01080.17 CDJ61981.1 - 0.08 11.7 0.1 0.079 11.7 0.1 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CDJ61981.1 - 0.32 10.9 9.1 0.45 10.5 9.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ61981.1 - 2.9 7.8 22.3 3.6 7.5 22.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ61981.1 - 7.2 4.7 14.0 8.3 4.5 14.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 rRNA_processing PF08524.11 CDJ61982.1 - 1.1e-06 28.7 33.8 8.7e-05 22.6 33.8 2.2 1 1 0 1 1 1 1 rRNA processing TFIIA PF03153.13 CDJ61982.1 - 0.71 9.8 21.8 0.93 9.4 21.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ61982.1 - 1.8 7.5 19.8 2.1 7.3 19.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SRP-alpha_N PF04086.13 CDJ61982.1 - 2.3 8.0 22.5 2.8 7.8 22.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal HAGH_C PF16123.5 CDJ61982.1 - 4.7 7.8 10.6 0.12 12.9 0.9 2.5 1 1 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus LAP1C PF05609.12 CDJ61982.1 - 6.2 5.8 18.3 7.1 5.6 18.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RskA PF10099.9 CDJ61982.1 - 7.2 6.9 28.5 0.017 15.4 9.8 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA CDC27 PF09507.10 CDJ61982.1 - 9.2 5.5 28.0 12 5.2 28.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CBF PF03914.17 CDJ61983.1 - 4.4e-15 56.1 0.0 1.9e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 CBF/Mak21 family OAD_gamma PF04277.13 CDJ61983.1 - 1.2 9.7 10.4 4.9 7.8 0.1 3.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain SUIM_assoc PF16619.5 CDJ61983.1 - 4.1 7.5 9.5 1 9.4 6.1 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 BTK PF00779.19 CDJ61985.1 - 0.018 14.8 6.9 0.018 14.8 6.9 3.6 4 0 0 4 4 4 0 BTK motif LIM PF00412.22 CDJ61985.1 - 0.51 10.6 12.0 3.8 7.8 4.1 2.3 2 0 0 2 2 2 0 LIM domain eIF2A PF08662.11 CDJ61986.1 - 2.1e-34 119.1 0.0 1e-31 110.3 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CDJ61986.1 - 0.054 13.8 0.0 0.39 11.1 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF5061 PF16587.5 CDJ61986.1 - 0.08 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 17 kDa common-antigen outer membrane protein Nudc_N PF14050.6 CDJ61987.1 - 2e-18 66.1 0.0 3.4e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 CDJ61987.1 - 1.2e-06 29.4 0.8 1.6e-05 25.8 0.8 2.3 1 1 0 1 1 1 1 CS domain RAP1 PF07218.11 CDJ61987.1 - 0.27 9.5 12.0 0.39 8.9 12.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Kelch_4 PF13418.6 CDJ61988.1 - 3.4e-37 126.2 4.9 4.6e-09 36.1 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ61988.1 - 1e-26 92.4 0.0 2.1e-06 27.6 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CDJ61988.1 - 1.8e-26 91.8 4.8 3.7e-07 30.3 0.0 7.4 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ61988.1 - 5.2e-20 71.0 3.5 5.8e-05 23.2 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 CDJ61988.1 - 2.9e-18 65.1 2.9 0.00017 21.1 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CDJ61988.1 - 4.6e-06 26.4 11.9 0.0041 17.0 0.0 6.5 7 1 0 7 7 6 1 Kelch motif APG6_N PF17675.1 CDJ61988.1 - 0.0013 19.3 7.2 0.0023 18.5 7.2 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Sec34 PF04136.15 CDJ61988.1 - 0.017 15.0 2.7 0.031 14.1 2.7 1.4 1 0 0 1 1 1 0 Sec34-like family GAT PF03127.14 CDJ61988.1 - 0.038 14.3 1.9 0.069 13.5 1.9 1.4 1 0 0 1 1 1 0 GAT domain TMPIT PF07851.13 CDJ61988.1 - 0.047 12.9 4.8 0.067 12.4 4.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Lebercilin PF15619.6 CDJ61988.1 - 0.078 12.6 9.2 0.13 11.9 9.2 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.12 CDJ61988.1 - 0.095 12.7 3.4 0.19 11.8 3.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 CDJ61988.1 - 0.12 12.7 8.4 0.048 13.9 3.5 2.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.6 CDJ61988.1 - 0.13 11.9 3.9 0.25 11.0 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) GAS PF13851.6 CDJ61988.1 - 0.14 11.5 9.7 0.23 10.8 9.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YscO PF07321.12 CDJ61988.1 - 0.17 11.8 10.8 0.31 11.0 10.8 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO Atg14 PF10186.9 CDJ61988.1 - 0.29 10.2 5.8 0.41 9.7 5.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TF_AP-2 PF03299.14 CDJ61988.1 - 0.3 11.0 6.7 0.32 10.9 3.7 2.0 2 0 0 2 2 2 0 Transcription factor AP-2 Phage_GPO PF05929.11 CDJ61988.1 - 0.48 10.0 8.7 0.78 9.3 8.7 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Syntaxin-6_N PF09177.11 CDJ61988.1 - 0.59 10.7 5.6 2.3 8.8 5.6 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal WXG100 PF06013.12 CDJ61988.1 - 0.68 10.2 11.3 1.9 8.7 10.7 2.1 1 1 0 1 1 1 0 Proteins of 100 residues with WXG SKA1 PF07160.12 CDJ61988.1 - 0.82 9.5 6.2 1.6 8.6 6.2 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF3450 PF11932.8 CDJ61988.1 - 0.83 8.9 15.7 0.41 9.9 11.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 CDJ61988.1 - 1.1 8.1 13.0 1.5 7.6 13.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ThiD2 PF17792.1 CDJ61988.1 - 1.3 9.5 3.9 2.6 8.5 3.9 1.5 1 0 0 1 1 1 0 ThiD2 family BLOC1_2 PF10046.9 CDJ61988.1 - 1.5 9.2 10.2 1.7 9.0 3.6 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 CDJ61988.1 - 1.9 8.6 7.4 4.2 7.6 7.4 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 CDJ61988.1 - 2.1 8.3 11.2 5.1 7.1 11.2 1.7 1 1 0 1 1 1 0 Laminin Domain II BRE1 PF08647.11 CDJ61988.1 - 2.8 8.1 11.6 5.1 7.2 11.6 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Vps51 PF08700.11 CDJ61988.1 - 2.9 8.0 6.2 5 7.3 1.0 2.5 2 0 0 2 2 2 0 Vps51/Vps67 KxDL PF10241.9 CDJ61988.1 - 4.5 7.6 8.6 22 5.4 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein Seryl_tRNA_N PF02403.22 CDJ61988.1 - 7.4 6.9 11.0 30 4.9 10.9 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain cNMP_binding PF00027.29 CDJ61990.1 - 2.2e-14 53.3 0.1 4.8e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain MRP_L53 PF10780.9 CDJ61993.1 - 0.0077 16.4 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 LPD29 PF18847.1 CDJ61993.1 - 0.1 13.5 0.0 0.13 13.3 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 29 DUF3583 PF12126.8 CDJ61994.1 - 0.25 10.8 10.7 0.34 10.3 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) NAP PF00956.18 CDJ61995.1 - 7.2e-52 176.2 0.0 7.2e-52 176.2 0.0 4.8 3 2 1 4 4 4 1 Nucleosome assembly protein (NAP) EMP70 PF02990.16 CDJ61996.1 - 0.25 9.9 3.0 0.82 8.3 0.6 2.2 2 0 0 2 2 2 0 Endomembrane protein 70 TFIIA PF03153.13 CDJ61996.1 - 1.2 9.0 51.2 1.3 8.9 8.4 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit UQ_con PF00179.26 CDJ61997.1 - 2.6e-13 49.8 0.0 3.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ61997.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain RRM_1 PF00076.22 CDJ61998.1 - 0.0026 17.5 0.0 0.0082 15.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RskA PF10099.9 CDJ61999.1 - 0.014 15.7 2.0 0.014 15.7 2.0 4.7 1 1 3 4 4 4 0 Anti-sigma-K factor rskA SARAF PF06682.12 CDJ61999.1 - 4.3 6.9 30.4 0.52 9.9 4.4 2.6 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis RT_RNaseH PF17917.1 CDJ62001.1 - 3.1e-30 104.5 0.0 6.2e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ62001.1 - 9.2e-30 102.6 0.1 1.6e-29 101.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ62001.1 - 6.1e-18 64.7 0.9 1.2e-17 63.7 0.9 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ62001.1 - 5.4e-12 46.0 0.0 2e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ62001.1 - 6.1e-05 23.1 0.3 0.00013 22.1 0.3 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 CDJ62001.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Ephrin_rec_like PF07699.13 CDJ62002.1 - 5.4e-16 58.1 38.9 4.1e-05 23.2 4.3 5.7 4 1 1 5 5 5 5 Putative ephrin-receptor like Kringle PF00051.18 CDJ62002.1 - 3.6e-15 56.1 2.7 8.3e-15 54.9 2.7 1.5 1 0 0 1 1 1 1 Kringle domain RANK_CRD_2 PF18278.1 CDJ62002.1 - 0.0014 18.7 0.2 0.0014 18.7 0.2 4.4 5 0 0 5 5 5 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 TFIIA PF03153.13 CDJ62003.1 - 0.63 10.0 12.9 0.89 9.5 12.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ62003.1 - 1.3 8.6 12.0 2.1 7.9 12.0 1.2 1 0 0 1 1 1 0 Spt20 family zf-MIZ PF02891.20 CDJ62004.1 - 2.5e-16 59.1 5.6 6.7e-16 57.8 5.6 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CDJ62004.1 - 0.02 14.7 2.2 0.043 13.6 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Integrase_H2C2 PF17921.1 CDJ62006.1 - 6.8e-15 54.9 0.5 2.1e-14 53.4 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 CDJ62006.1 - 3.5e-11 42.9 0.0 6.3e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CDJ62006.1 - 0.0025 18.0 0.2 0.0067 16.6 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Mvb12 PF09452.10 CDJ62006.1 - 0.067 13.6 0.1 0.24 11.9 0.1 1.9 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 Asp_protease_2 PF13650.6 CDJ62007.1 - 1.7e-07 31.8 0.0 3.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ62007.1 - 6.6e-07 29.8 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ62007.1 - 1.6e-05 24.7 0.0 2.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CDJ62007.1 - 0.059 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.12 CDJ62007.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 CDJ62007.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease cNMP_binding PF00027.29 CDJ62009.1 - 7.7e-59 195.8 3.2 4.3e-19 68.4 0.0 5.1 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CDJ62009.1 - 7.9e-06 25.5 1.5 0.94 9.2 0.0 5.0 5 0 0 5 5 5 2 Cupin domain CRT10 PF08728.10 CDJ62009.1 - 0.45 8.6 6.2 1.4 7.0 6.1 1.8 2 0 0 2 2 2 0 CRT10 Draxin PF15550.6 CDJ62009.1 - 0.81 9.5 19.8 1.5 8.6 19.8 1.4 1 0 0 1 1 1 0 Draxin DHC_N1 PF08385.12 CDJ62011.1 - 3.1e-120 402.5 6.2 3.1e-120 402.5 6.2 3.5 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CDJ62011.1 - 8.2e-114 380.8 10.3 8.2e-114 380.8 10.3 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 PSD1 PF07587.11 CDJ62011.1 - 0.00046 19.7 1.7 0.12 11.9 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1553) INCENP_N PF12178.8 CDJ62011.1 - 0.052 13.6 0.2 2.5 8.2 0.0 3.3 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal SR-25 PF10500.9 CDJ62011.1 - 0.21 11.1 19.1 0.041 13.5 14.0 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ORC_WH_C PF18137.1 CDJ62011.1 - 5 7.2 6.8 0.85 9.7 0.3 2.8 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal AAA_6 PF12774.7 CDJ62012.1 - 4.4e-18 65.3 0.0 4.5e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CDJ62013.1 - 8e-83 277.7 0.0 3.7e-81 272.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ62013.1 - 9.2e-77 257.1 2.1 2.9e-76 255.4 2.1 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDJ62013.1 - 8.8e-66 220.9 0.1 2.8e-65 219.2 0.1 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region MT PF12777.7 CDJ62013.1 - 2.5e-60 204.3 15.5 6.2e-60 203.0 15.7 1.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 CDJ62013.1 - 2.3e-48 164.8 0.1 8e-47 159.8 0.0 3.2 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 CDJ62013.1 - 3.6e-24 85.3 2.0 1.3e-23 83.5 2.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ62013.1 - 1.5e-22 79.7 0.0 3.5e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ62013.1 - 7.7e-16 58.3 0.0 2.7e-05 24.2 0.0 4.5 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CDJ62013.1 - 6.9e-05 23.4 1.7 0.0011 19.5 0.0 3.1 4 0 0 4 4 2 1 ABC transporter AAA_29 PF13555.6 CDJ62013.1 - 0.00041 20.0 0.1 0.04 13.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.6 CDJ62013.1 - 0.0015 18.6 0.5 0.011 15.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 CDJ62013.1 - 0.0029 16.8 0.0 0.15 11.2 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 CDJ62013.1 - 0.0031 17.9 9.5 0.0057 17.1 0.0 4.7 5 1 1 6 6 6 1 AAA ATPase domain AAA_22 PF13401.6 CDJ62013.1 - 0.0073 16.6 0.0 0.074 13.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain TniB PF05621.11 CDJ62013.1 - 0.013 14.9 0.0 0.17 11.3 0.0 2.7 2 0 0 2 2 2 0 Bacterial TniB protein Mg_chelatase PF01078.21 CDJ62013.1 - 0.022 14.2 0.0 1.5 8.1 0.0 2.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CDJ62013.1 - 0.024 14.3 0.1 2.8 7.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 CDJ62013.1 - 0.043 14.0 0.2 2.4 8.3 0.0 3.7 3 1 0 3 3 3 0 AAA domain G-alpha PF00503.20 CDJ62013.1 - 0.072 12.2 0.0 0.072 12.2 0.0 2.8 4 0 0 4 4 3 0 G-protein alpha subunit DUF573 PF04504.14 CDJ62013.1 - 0.086 13.5 0.2 0.63 10.7 0.2 2.5 2 0 0 2 2 1 0 Protein of unknown function, DUF573 RsgA_GTPase PF03193.16 CDJ62013.1 - 0.095 12.6 0.1 1.6 8.7 0.0 2.9 3 0 0 3 3 2 0 RsgA GTPase AAA PF00004.29 CDJ62013.1 - 0.12 12.8 0.0 2.6 8.5 0.0 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CDJ62013.1 - 0.13 12.2 0.0 0.56 10.2 0.0 2.1 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 CDJ62013.1 - 0.15 11.7 0.1 5.8 6.5 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 CDJ62013.1 - 0.18 12.1 0.3 4.2 7.7 0.0 2.9 2 1 1 3 3 3 0 AAA domain ISG65-75 PF11727.8 CDJ62013.1 - 5.6 6.1 21.7 0.77 8.9 11.0 2.3 2 0 0 2 2 2 0 Invariant surface glycoprotein Dynein_heavy PF03028.15 CDJ62014.1 - 1.2e-07 31.9 0.0 2.6e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 CDJ62015.1 - 6.2e-57 193.1 0.0 4.7e-45 154.1 0.0 2.1 1 1 1 2 2 2 2 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CDJ62015.1 - 3.8e-41 140.7 0.0 5.8e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ62015.1 - 2e-24 85.9 0.0 2e-23 82.7 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain PRY PF13765.6 CDJ62016.1 - 3.6 7.3 4.9 1.4 8.6 0.3 2.5 3 0 0 3 3 3 0 SPRY-associated domain G0-G1_switch_2 PF15103.6 CDJ62017.1 - 0.1 13.1 0.7 0.32 11.4 0.7 1.9 1 0 0 1 1 1 0 G0/G1 switch protein 2 LRR_4 PF12799.7 CDJ62020.1 - 1.4e-12 47.6 15.0 5.2e-07 29.9 0.4 4.0 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ62020.1 - 8.4e-11 41.5 14.4 8.9e-05 22.2 0.2 3.7 2 2 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 CDJ62020.1 - 9.7e-06 25.2 0.8 0.0075 15.8 0.6 2.1 2 0 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CDJ62020.1 - 7.2e-05 22.5 15.8 0.02 14.9 0.2 5.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 CDJ62020.1 - 0.042 14.4 10.8 0.85 10.4 0.0 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat DUF5450 PF17529.2 CDJ62020.1 - 0.048 13.8 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5450) DUF3350 PF11830.8 CDJ62021.1 - 0.047 14.0 1.1 1.9 8.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) LRR_8 PF13855.6 CDJ62022.1 - 1.8e-05 24.4 4.4 0.00018 21.2 0.1 3.0 3 0 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.6 CDJ62022.1 - 0.0034 16.9 0.2 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 CDJ62022.1 - 0.026 15.0 1.5 0.026 15.0 1.5 3.2 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ62022.1 - 0.29 11.8 2.2 20 6.2 0.7 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_9 PF14580.6 CDJ62023.1 - 1.3e-30 106.1 3.3 1.7e-11 44.0 0.1 4.6 2 2 3 5 5 5 4 Leucine-rich repeat LRR_8 PF13855.6 CDJ62023.1 - 1.4e-27 95.2 17.8 2.3e-06 27.3 1.3 6.1 4 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 CDJ62023.1 - 3.2e-26 90.9 26.5 4.5e-05 23.7 0.4 7.5 5 2 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ62023.1 - 2.3e-07 30.3 26.0 0.062 13.4 0.3 8.9 10 0 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.33 CDJ62023.1 - 8.7e-06 25.6 30.8 0.42 11.3 0.0 9.2 10 0 0 10 10 10 4 Leucine Rich Repeat LisH_2 PF16045.5 CDJ62024.1 - 0.0062 15.5 0.3 0.016 14.2 0.3 1.7 1 0 0 1 1 1 1 LisH DUF836 PF05768.14 CDJ62024.1 - 0.07 13.5 0.3 0.1 13.0 0.3 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Androgen_recep PF02166.16 CDJ62025.1 - 0.016 14.1 2.1 0.019 13.8 2.1 1.1 1 0 0 1 1 1 0 Androgen receptor Chorion_2 PF03964.15 CDJ62026.1 - 0.0008 20.2 3.3 0.00087 20.1 3.3 1.1 1 0 0 1 1 1 1 Chorion family 2 DUF3446 PF11928.8 CDJ62026.1 - 0.011 16.0 14.2 0.017 15.4 14.2 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain Pom PF17251.2 CDJ62026.1 - 0.012 15.0 1.2 0.014 14.7 1.2 1.1 1 0 0 1 1 1 0 Protochlamydia outer membrane protein Secretin_N_2 PF07655.13 CDJ62026.1 - 0.02 15.4 13.8 0.026 15.0 13.8 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain AF-4 PF05110.13 CDJ62026.1 - 0.031 12.4 18.3 0.031 12.4 18.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF515 PF04415.12 CDJ62026.1 - 0.11 10.8 8.3 0.12 10.7 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DA1-like PF12315.8 CDJ62026.1 - 0.14 11.6 0.7 0.15 11.5 0.7 1.1 1 0 0 1 1 1 0 Protein DA1 SR-25 PF10500.9 CDJ62026.1 - 0.19 11.3 24.8 0.24 11.0 24.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Kinesin_assoc PF16183.5 CDJ62026.1 - 0.19 11.8 0.6 0.23 11.6 0.6 1.1 1 0 0 1 1 1 0 Kinesin-associated Lin-8 PF03353.15 CDJ62026.1 - 0.25 10.9 4.6 0.28 10.7 4.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist EBP50_C PF09007.11 CDJ62026.1 - 0.38 11.7 8.2 0.51 11.3 8.2 1.1 1 0 0 1 1 1 0 EBP50, C-terminal Corona_nucleoca PF00937.18 CDJ62026.1 - 0.86 8.6 10.2 0.99 8.4 10.2 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CCDC106 PF15794.5 CDJ62026.1 - 0.99 9.1 8.7 1.2 8.8 8.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 FAM199X PF15814.5 CDJ62026.1 - 1.1 8.3 12.5 1.2 8.1 12.5 1.0 1 0 0 1 1 1 0 Protein family FAM199X DUF1635 PF07795.11 CDJ62026.1 - 2.2 8.1 8.4 2.6 7.8 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Macoilin PF09726.9 CDJ62026.1 - 3.7 6.0 9.8 4.2 5.8 9.8 1.0 1 0 0 1 1 1 0 Macoilin family SSP160 PF06933.11 CDJ62026.1 - 4.3 5.4 13.8 4.7 5.3 13.8 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Herpes_capsid PF06112.11 CDJ62026.1 - 4.4 7.4 14.3 5.9 6.9 14.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CCDC24 PF15669.5 CDJ62026.1 - 4.7 7.0 8.0 5.7 6.7 8.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family zf-RING_2 PF13639.6 CDJ62027.1 - 0.0024 18.2 2.2 0.0034 17.7 2.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDJ62027.1 - 0.0057 16.4 1.2 0.0057 16.4 1.2 1.5 2 0 0 2 2 2 1 RING-like zinc finger Afi1 PF07792.12 CDJ62028.1 - 0.15 12.5 0.3 0.15 12.5 0.3 3.1 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4834 PF16118.5 CDJ62029.1 - 0.026 15.5 1.3 0.035 15.1 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM208_SND2 PF05620.11 CDJ62029.1 - 6.8 6.4 7.2 9.3 6.0 7.2 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Peptidase_S8 PF00082.22 CDJ62030.1 - 3.2e-11 43.1 0.7 3.2e-11 43.1 0.7 2.7 4 0 0 4 4 4 1 Subtilase family SRP9-21 PF05486.12 CDJ62030.1 - 0.5 10.8 4.7 7.4 7.0 0.1 2.7 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) DUF572 PF04502.13 CDJ62030.1 - 0.56 9.8 10.6 1.1 8.9 10.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2722 PF10846.8 CDJ62030.1 - 2.3 7.0 30.4 0.14 11.1 12.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) ALMT PF11744.8 CDJ62030.1 - 2.4 6.9 10.0 3.5 6.3 10.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3381 PF11861.8 CDJ62030.1 - 3.6 7.4 20.0 0.93 9.3 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) RT_RNaseH PF17917.1 CDJ62031.1 - 6.4e-10 39.3 1.5 8e-10 39.0 0.9 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ62031.1 - 8.6e-05 22.5 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ62031.1 - 0.078 13.2 0.2 6.8 6.9 0.0 2.1 1 1 1 2 2 2 0 Integrase core domain Tmemb_18A PF09771.9 CDJ62031.1 - 0.13 12.7 0.1 0.16 12.4 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 188 DUF4911 PF16256.5 CDJ62031.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Ribosomal_L44 PF00935.19 CDJ62033.1 - 1.8e-35 121.2 11.8 2.4e-35 120.9 11.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 DUF4106 PF13388.6 CDJ62034.1 - 4.4 6.4 7.3 5.3 6.2 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF755 PF05501.11 CDJ62035.1 - 0.009 16.3 17.8 0.009 16.3 17.8 10.5 9 2 1 10 10 10 1 Domain of unknown function (DUF755) DUF5411 PF17424.2 CDJ62036.1 - 7.6e-05 22.7 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5411) DUF2722 PF10846.8 CDJ62036.1 - 0.0073 15.3 5.3 0.0073 15.3 5.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ62036.1 - 0.022 15.4 7.9 0.022 15.4 7.9 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YajC PF02699.15 CDJ62036.1 - 0.075 12.9 0.5 0.075 12.9 0.5 2.4 2 0 0 2 2 2 0 Preprotein translocase subunit EphA2_TM PF14575.6 CDJ62036.1 - 0.083 13.8 1.2 7.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.6 CDJ62036.1 - 0.21 11.9 2.3 2.4 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4834 PF16118.5 CDJ62036.1 - 0.27 12.2 2.2 1.2 10.2 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CDK2AP PF09806.9 CDJ62036.1 - 0.58 10.2 14.5 1.3 9.0 14.5 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein FTZ PF03867.14 CDJ62036.1 - 1.8 8.0 12.5 0.41 10.1 6.3 2.0 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region RCR PF12273.8 CDJ62036.1 - 6.6 7.4 10.3 24 5.6 10.1 1.9 1 1 1 2 2 2 0 Chitin synthesis regulation, resistance to Congo red KR PF08659.10 CDJ62037.1 - 1.6e-32 112.8 0.0 1.8e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 CDJ62037.1 - 3.3e-05 23.4 0.0 4.1e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ62038.1 - 8.5e-129 426.5 0.1 1e-58 198.2 0.0 3.7 3 0 0 3 3 3 3 KR domain ketoacyl-synt PF00109.26 CDJ62038.1 - 1.6e-120 401.4 0.4 8.9e-73 245.0 0.1 3.7 2 1 1 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 CDJ62038.1 - 3e-84 282.8 4.2 1.8e-45 155.5 0.1 2.3 2 0 0 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CDJ62038.1 - 3e-81 269.2 8.1 9.1e-41 138.6 0.2 3.3 3 0 0 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 CDJ62038.1 - 2.3e-50 171.9 0.1 4e-50 171.1 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.25 CDJ62038.1 - 3.4e-27 95.2 2.6 1.2e-11 44.4 0.0 4.3 5 0 0 5 5 5 3 short chain dehydrogenase ADH_zinc_N PF00107.26 CDJ62038.1 - 3.6e-24 85.2 0.3 1e-12 48.1 0.0 4.4 4 0 0 4 4 4 3 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDJ62038.1 - 5.9e-23 82.4 0.0 2.6e-09 38.2 0.0 3.9 3 0 0 3 3 3 2 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 CDJ62038.1 - 4.5e-17 62.5 0.0 2.7e-08 34.3 0.0 2.7 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension adh_short_C2 PF13561.6 CDJ62038.1 - 7.2e-17 61.7 0.0 2.4e-07 30.5 0.0 2.7 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CDJ62038.1 - 4.4e-14 52.5 0.0 3e-05 23.6 0.0 3.4 3 0 0 3 3 3 3 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CDJ62038.1 - 1.6e-12 47.6 0.0 3.9e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 CDJ62038.1 - 4.1e-10 39.5 6.2 0.00026 20.8 0.0 3.5 4 0 0 4 4 3 2 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.15 CDJ62038.1 - 4.8e-10 39.1 0.0 0.0019 17.4 0.0 3.4 3 0 0 3 3 3 3 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CDJ62038.1 - 2.8e-08 33.1 0.0 0.00042 19.4 0.0 3.4 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CDJ62038.1 - 9e-06 25.3 0.0 0.2 11.0 0.0 3.3 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 CDJ62038.1 - 0.00017 21.1 0.1 0.00069 19.1 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain AlaDh_PNT_C PF01262.21 CDJ62038.1 - 0.00046 19.5 3.1 0.2 10.9 0.3 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 CDJ62038.1 - 0.029 14.4 0.2 17 5.5 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 CDJ62038.1 - 0.075 12.9 0.0 7.5 6.4 0.0 3.3 2 0 0 2 2 2 0 NAD(P)H-binding 4HB PF17947.1 CDJ62038.1 - 0.15 12.2 0.0 0.44 10.7 0.0 1.8 1 0 0 1 1 1 0 Four helical bundle domain ACP_syn_III PF08545.10 CDJ62038.1 - 0.19 11.6 3.0 0.36 10.7 0.8 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ELFV_dehydrog PF00208.21 CDJ62038.1 - 0.91 9.2 10.5 2.8 7.6 0.0 4.2 5 0 0 5 5 5 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ApbA PF02558.16 CDJ62038.1 - 5 6.8 7.1 2.3 7.9 0.3 3.4 4 0 0 4 4 3 0 Ketopantoate reductase PanE/ApbA DUF3391 PF11871.8 CDJ62039.1 - 0.92 10.1 5.4 0.65 10.5 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) RT_RNaseH_2 PF17919.1 CDJ62041.1 - 4.3e-28 97.3 0.0 4.9e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ62041.1 - 1.9e-17 63.4 0.0 2.8e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Scramblase PF03803.15 CDJ62041.1 - 0.07 12.4 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 Scramblase Zeta_toxin PF06414.12 CDJ62041.1 - 0.12 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin PSI_PsaF PF02507.15 CDJ62041.1 - 0.13 12.1 0.0 6.3 6.6 0.0 2.0 1 1 1 2 2 2 0 Photosystem I reaction centre subunit III FAM92 PF06730.11 CDJ62041.1 - 0.16 11.3 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 FAM92 protein rve PF00665.26 CDJ62042.1 - 3.9e-11 43.2 0.0 8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ62042.1 - 0.13 12.1 0.1 0.41 10.5 0.1 1.9 2 0 0 2 2 2 0 Integrase core domain rve PF00665.26 CDJ62043.1 - 1.9e-07 31.3 0.0 3.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ62043.1 - 0.00013 21.8 0.3 0.00036 20.4 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RNR_Alpha PF17975.1 CDJ62043.1 - 0.088 13.3 0.1 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain Apt1 PF10351.9 CDJ62044.1 - 0.3 9.9 4.9 0.35 9.7 4.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SASRP1 PF15160.6 CDJ62044.1 - 9.6 5.8 10.5 14 5.3 10.5 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 Pkinase PF00069.25 CDJ62045.1 - 3.1e-07 30.1 0.0 5.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ62045.1 - 3.3e-06 26.6 0.0 1.5e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ62045.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase MOZART1 PF12554.8 CDJ62046.1 - 1.6e-20 72.6 0.6 2.4e-20 72.0 0.6 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated p450 PF00067.22 CDJ62046.1 - 0.022 13.5 0.2 0.022 13.5 0.2 1.0 1 0 0 1 1 1 0 Cytochrome P450 Gasdermin_C PF17708.1 CDJ62046.1 - 0.046 13.8 0.2 0.052 13.7 0.2 1.1 1 0 0 1 1 1 0 Gasdermin PUB domain Tubulin PF00091.25 CDJ62047.1 - 3.2e-68 229.8 0.0 6.1e-68 228.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ62047.1 - 3e-42 143.8 0.0 4.5e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDJ62047.1 - 0.00028 21.2 0.0 0.00073 19.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CDJ62047.1 - 0.0053 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 CDJ62047.1 - 0.0065 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF202 PF02656.15 CDJ62048.1 - 6.6e-05 23.3 0.1 0.032 14.7 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF202) Hydrolase PF00702.26 CDJ62050.1 - 0.004 17.5 0.0 0.034 14.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase IL17_R_N PF15037.6 CDJ62050.1 - 0.039 12.9 0.0 0.056 12.4 0.0 1.1 1 0 0 1 1 1 0 Interleukin-17 receptor extracellular region Acid_PPase PF12689.7 CDJ62050.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase Mcl1_mid PF12341.8 CDJ62051.1 - 1e-08 34.9 0.0 2.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region LRR_8 PF13855.6 CDJ62052.1 - 4.8e-10 39.1 1.9 2.7e-05 23.8 0.0 3.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CDJ62052.1 - 8.4e-08 32.4 3.5 0.031 14.7 0.0 5.0 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ62052.1 - 7.9e-05 22.4 1.7 8.1 6.8 0.0 6.3 7 0 0 7 7 7 1 Leucine Rich repeat adh_short PF00106.25 CDJ62053.1 - 4.2e-28 98.1 3.7 5.3e-26 91.3 3.7 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ62053.1 - 9.9e-11 41.6 3.1 3.6e-09 36.5 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ62053.1 - 1.2e-06 28.5 1.8 2.1e-05 24.5 1.8 2.2 1 1 0 1 1 1 1 KR domain YjeF_N PF03853.15 CDJ62053.1 - 0.017 15.0 0.2 0.049 13.5 0.1 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus Epimerase PF01370.21 CDJ62053.1 - 0.018 14.5 0.3 1.6 8.1 0.1 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDJ62053.1 - 0.046 12.9 0.1 0.064 12.4 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 CDJ62053.1 - 0.071 12.4 0.4 0.17 11.2 0.4 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 CDJ62053.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Thioredoxin_7 PF13899.6 CDJ62056.1 - 5.4e-12 45.7 0.3 1.2e-11 44.6 0.3 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 CDJ62056.1 - 3e-07 30.1 0.0 5.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain DnaT PF17948.1 CDJ62056.1 - 0.66 9.7 3.1 1 9.1 0.1 2.7 3 0 0 3 3 3 0 DnaT DNA-binding domain RAP1 PF07218.11 CDJ62056.1 - 1.8 6.8 5.1 2.2 6.4 5.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAM199X PF15814.5 CDJ62056.1 - 4.2 6.3 8.1 6.2 5.8 8.1 1.1 1 0 0 1 1 1 0 Protein family FAM199X ABC_membrane PF00664.23 CDJ62057.1 - 1.8e-68 231.1 18.6 2.1e-47 162.1 1.6 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ62057.1 - 2.8e-65 219.0 0.0 7e-33 114.0 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDJ62057.1 - 3.7e-14 52.7 6.5 5.9e-07 29.1 0.9 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CDJ62057.1 - 6.4e-08 33.0 0.7 0.069 13.4 0.1 4.0 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CDJ62057.1 - 4e-07 30.6 6.5 0.015 15.7 0.3 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CDJ62057.1 - 4.2e-07 29.6 0.1 0.023 14.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ62057.1 - 5.8e-07 29.6 0.0 0.034 14.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 CDJ62057.1 - 6.8e-07 29.2 0.5 0.0041 16.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 CDJ62057.1 - 1.2e-06 27.7 1.3 0.1 11.4 0.1 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 CDJ62057.1 - 3.6e-06 26.9 0.0 0.014 15.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 CDJ62057.1 - 9.9e-06 25.3 0.2 0.63 9.6 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_21 PF13304.6 CDJ62057.1 - 1.1e-05 25.4 0.0 0.3 10.8 0.0 3.8 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 CDJ62057.1 - 1.5e-05 25.1 0.1 0.09 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ62057.1 - 2e-05 25.0 1.1 0.17 12.3 0.0 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDJ62057.1 - 4.2e-05 23.1 0.0 0.078 12.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 CDJ62057.1 - 5.1e-05 23.6 0.3 0.13 12.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 CDJ62057.1 - 7e-05 22.8 0.2 0.28 11.1 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain ATP-synt_ab PF00006.25 CDJ62057.1 - 9.2e-05 22.2 0.2 0.42 10.2 0.0 3.0 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 CDJ62057.1 - 0.00032 20.5 1.9 5.8 6.6 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein G-alpha PF00503.20 CDJ62057.1 - 0.00035 19.9 0.0 0.56 9.3 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit Zeta_toxin PF06414.12 CDJ62057.1 - 0.00053 19.3 0.0 0.6 9.3 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin SbcCD_C PF13558.6 CDJ62057.1 - 0.00058 20.0 4.8 0.5 10.6 0.4 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 CDJ62057.1 - 0.00084 19.9 1.1 4.1 8.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 CDJ62057.1 - 0.001 18.4 0.0 0.8 8.8 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain AAA_23 PF13476.6 CDJ62057.1 - 0.0012 19.3 0.9 2 8.9 0.1 2.6 2 1 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 CDJ62057.1 - 0.0015 18.5 1.6 3.1 7.7 0.3 4.0 3 1 0 3 3 3 1 NTPase MMR_HSR1 PF01926.23 CDJ62057.1 - 0.0026 17.8 0.1 2.5 8.2 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase PRK PF00485.18 CDJ62057.1 - 0.0056 16.4 0.1 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 CDJ62057.1 - 0.0074 16.0 0.0 0.47 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CDJ62057.1 - 0.0095 15.3 0.9 9.1 5.6 0.0 3.6 3 0 0 3 3 3 0 KaiC RNA_helicase PF00910.22 CDJ62057.1 - 0.0098 16.3 0.2 5.8 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase TniB PF05621.11 CDJ62057.1 - 0.015 14.7 0.4 13 5.1 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein AAA_14 PF13173.6 CDJ62057.1 - 0.019 15.0 1.2 6.6 6.8 0.0 3.4 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 CDJ62057.1 - 0.025 14.5 4.3 7.8 6.4 0.0 3.7 4 0 0 4 4 4 0 NACHT domain Viral_helicase1 PF01443.18 CDJ62057.1 - 0.029 14.1 0.3 9.7 5.8 0.0 3.0 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 CDJ62057.1 - 0.047 13.8 0.3 8.3 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CDJ62057.1 - 0.059 13.7 0.3 7 7.0 0.1 3.1 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 CDJ62057.1 - 0.086 12.0 0.0 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 CDJ62057.1 - 0.11 12.2 0.5 20 4.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 CDJ62057.1 - 0.14 12.4 0.1 21 5.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CDJ62057.1 - 0.16 12.0 0.0 19 5.3 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 CDJ62057.1 - 0.27 11.7 6.9 7 7.1 0.4 3.7 4 0 0 4 4 3 0 AAA domain Phage_holin_5_1 PF06946.11 CDJ62057.1 - 0.47 10.9 3.3 0.81 10.1 0.1 2.8 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 Thioredoxin PF00085.20 CDJ62058.1 - 4.2e-17 62.0 0.3 6e-06 26.2 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 CDJ62058.1 - 2.6e-13 50.3 5.0 0.00044 20.2 1.4 3.5 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ62058.1 - 3.2e-07 30.6 1.7 0.48 10.8 0.1 3.6 3 1 0 3 3 3 3 Thioredoxin-like Thioredoxin_2 PF13098.6 CDJ62058.1 - 4.6e-05 23.8 0.2 0.45 11.0 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CDJ62058.1 - 0.00086 18.7 6.6 0.55 9.5 0.7 3.1 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family TraF PF13728.6 CDJ62058.1 - 0.017 15.0 0.5 6.3 6.5 0.0 3.4 3 1 0 3 3 3 0 F plasmid transfer operon protein TrbC_Ftype PF09673.10 CDJ62058.1 - 0.2 11.7 3.4 8.2 6.5 0.1 3.6 2 2 2 4 4 4 0 Type-F conjugative transfer system pilin assembly protein Peptidase_C12 PF01088.21 CDJ62059.1 - 2.6e-18 66.6 0.0 3e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pkinase PF00069.25 CDJ62060.1 - 3e-05 23.5 2.1 4.2e-05 23.0 0.1 2.1 2 1 1 3 3 3 1 Protein kinase domain RskA PF10099.9 CDJ62060.1 - 0.0036 17.6 20.7 0.0036 17.6 20.7 4.0 2 2 2 4 4 4 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ62060.1 - 0.0047 17.9 13.2 2.1 9.4 1.2 3.8 4 0 0 4 4 4 3 Domain of unknown function (DUF4834) Pkinase_Tyr PF07714.17 CDJ62060.1 - 0.0098 15.2 0.1 0.023 14.0 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_60s PF00428.19 CDJ62060.1 - 1 10.0 29.8 15 6.2 16.0 3.9 4 0 0 4 4 4 0 60s Acidic ribosomal protein DUF4179 PF13786.6 CDJ62060.1 - 3.6 8.1 10.9 4.8 7.7 0.2 3.3 3 1 0 4 4 4 0 Domain of unknown function (DUF4179) Spt20 PF12090.8 CDJ62060.1 - 4.5 6.8 46.4 0.66 9.6 12.4 3.3 3 0 0 3 3 3 0 Spt20 family Fumble PF03630.14 CDJ62061.1 - 1e-42 146.5 8.6 1e-22 80.8 0.3 4.5 2 1 1 3 3 3 3 Fumble RskA PF10099.9 CDJ62061.1 - 5.8e-05 23.5 5.4 5.8e-05 23.5 5.4 6.3 4 2 1 5 5 5 3 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ62061.1 - 0.0023 17.0 0.3 0.0023 17.0 0.3 4.5 5 0 0 5 5 5 3 Protein of unknown function (DUF2722) Sin_N PF04801.13 CDJ62061.1 - 0.0053 16.0 27.5 0.015 14.6 18.8 2.4 2 1 0 2 2 2 2 Sin-like protein conserved region DUF1645 PF07816.11 CDJ62061.1 - 0.0054 17.3 7.5 0.0054 17.3 7.5 6.8 4 3 0 4 4 4 1 Protein of unknown function (DUF1645) TFIIA PF03153.13 CDJ62061.1 - 0.012 15.6 16.9 0.012 15.6 16.9 5.2 3 2 1 5 5 5 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 CDJ62061.1 - 0.35 9.6 10.4 2.5 6.8 10.3 2.2 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein CagX PF03524.15 CDJ62061.1 - 1 9.1 12.2 17 5.1 0.2 3.5 3 0 0 3 3 3 0 Conjugal transfer protein CLN3 PF02487.17 CDJ62061.1 - 1.9 7.5 10.0 5.4 6.0 2.7 3.2 3 0 0 3 3 3 0 CLN3 protein MMM1 PF10296.9 CDJ62061.1 - 5.6 5.9 14.6 1.2 8.1 0.1 3.4 3 0 0 3 3 3 0 Maintenance of mitochondrial morphology protein 1 DXP_synthase_N PF13292.6 CDJ62062.1 - 1.3e-24 86.9 0.0 2.7e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase SPX PF03105.19 CDJ62062.1 - 0.0018 18.3 2.6 0.013 15.4 2.6 1.9 1 1 0 1 1 1 1 SPX domain DUF4614 PF15391.6 CDJ62062.1 - 3.1 7.8 17.4 0.8 9.7 6.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DXP_synthase_N PF13292.6 CDJ62063.1 - 8.4e-50 169.5 0.0 1.5e-49 168.6 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 CDJ62063.1 - 1e-15 57.8 0.0 2.7e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CDJ62063.1 - 0.00039 19.5 0.1 0.00084 18.4 0.1 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 CDJ62063.1 - 0.00045 19.3 0.0 0.096 11.6 0.0 2.3 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain TFIIA PF03153.13 CDJ62063.1 - 0.095 12.7 12.6 0.13 12.3 4.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ62064.1 - 0.00013 21.7 14.1 0.00013 21.7 14.1 2.4 2 0 0 2 2 2 2 Spt20 family SUIM_assoc PF16619.5 CDJ62064.1 - 0.02 14.9 2.1 0.02 14.9 2.1 3.6 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 G0-G1_switch_2 PF15103.6 CDJ62064.1 - 0.37 11.2 3.4 1 9.8 0.4 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 SLC12 PF03522.15 CDJ62064.1 - 0.58 9.1 4.6 0.99 8.4 4.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF4834 PF16118.5 CDJ62064.1 - 6.5 7.8 14.4 9.4 7.3 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CPSF100_C PF13299.6 CDJ62064.1 - 9.7 6.3 11.2 13 6.0 2.4 3.1 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal CwfJ_C_1 PF04677.15 CDJ62065.1 - 2.4e-24 85.5 0.0 3.9e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.22 CDJ62065.1 - 2.3e-07 30.5 0.0 4.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CwfJ_C_2 PF04676.14 CDJ62065.1 - 3.8e-07 30.9 0.0 1.3e-06 29.2 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Sin_N PF04801.13 CDJ62065.1 - 1.2 8.3 3.8 1.8 7.7 3.8 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region AhpC-TSA PF00578.21 CDJ62066.1 - 4.9e-29 100.8 0.0 6.1e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ62066.1 - 2.4e-12 46.8 0.0 3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDJ62066.1 - 6.7e-09 35.4 0.2 1.1e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 CDJ62066.1 - 0.019 15.1 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Orthopox_C10L PF07020.11 CDJ62067.1 - 1.1 10.1 133.8 1.4 9.7 11.3 9.9 2 2 3 5 5 5 0 Orthopoxvirus C10L protein Octopine_DH PF02317.17 CDJ62068.1 - 5.1e-38 130.5 0.0 7.1e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain PDH PF02153.17 CDJ62068.1 - 0.00087 18.4 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 CDJ62068.1 - 0.0029 18.2 0.5 0.0091 16.6 0.0 2.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 CDJ62068.1 - 0.0062 16.5 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 CDJ62068.1 - 0.018 14.7 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF4834 PF16118.5 CDJ62069.1 - 0.03 15.3 2.1 0.038 15.0 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2207 PF09972.9 CDJ62069.1 - 0.072 11.8 1.7 0.072 11.9 1.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC2_membrane_3 PF12698.7 CDJ62069.1 - 3.3 6.7 12.6 3.9 6.5 12.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ASFV_J13L PF05568.11 CDJ62069.1 - 5.3 6.8 9.3 0.21 11.3 1.3 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein MCM_bind PF09739.9 CDJ62070.1 - 1.6e-12 46.7 53.4 3.7e-08 32.3 0.0 8.4 3 2 6 9 9 9 5 Mini-chromosome maintenance replisome factor Pex14_N PF04695.13 CDJ62070.1 - 4.5e-05 24.1 41.0 0.046 14.4 7.5 5.7 5 0 0 5 5 5 4 Peroxisomal membrane anchor protein (Pex14p) conserved region Herpes_IE2_3 PF03361.14 CDJ62070.1 - 0.02 14.7 1.5 0.058 13.3 1.5 1.7 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Med15 PF09606.10 CDJ62070.1 - 0.031 13.0 48.6 0.026 13.2 4.5 3.3 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal PT-TG PF14449.6 CDJ62070.1 - 0.33 10.9 0.1 0.33 10.9 0.1 2.1 2 0 0 2 2 2 0 Pre-toxin TG RAP PF08373.10 CDJ62071.1 - 0.0086 16.2 0.1 0.023 14.8 0.1 1.7 1 0 0 1 1 1 1 RAP domain DUF559 PF04480.12 CDJ62071.1 - 0.047 13.6 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF559) FAST_1 PF06743.15 CDJ62071.1 - 0.22 11.5 5.9 20 5.2 1.1 4.8 3 2 2 5 5 5 0 FAST kinase-like protein, subdomain 1 AP-5_subunit_s1 PF15001.6 CDJ62072.1 - 3.7e-19 69.5 0.4 2.3e-18 66.9 0.4 2.1 1 1 0 1 1 1 1 AP-5 complex subunit sigma-1 B9-C2 PF07162.11 CDJ62073.1 - 9.1e-21 74.8 0.2 1.2e-20 74.4 0.2 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF2722 PF10846.8 CDJ62073.1 - 0.027 13.4 1.7 0.027 13.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RNA_GG_bind PF10258.9 CDJ62074.1 - 9.6e-19 67.2 0.0 2.2e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 PHAX RNA-binding domain Ank_4 PF13637.6 CDJ62075.1 - 3.6e-08 33.8 0.4 6.1e-05 23.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ62075.1 - 1.1e-07 32.4 0.0 3.2e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ62075.1 - 5.4e-07 29.4 0.2 0.16 12.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CDJ62075.1 - 0.00061 20.1 3.9 0.01 16.2 0.2 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CDJ62075.1 - 0.0048 17.2 0.1 1.1 9.6 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RskA PF10099.9 CDJ62075.1 - 0.018 15.3 5.4 0.018 15.3 5.4 6.0 1 1 2 4 4 4 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ62075.1 - 0.02 14.9 14.2 0.02 14.9 14.2 8.8 6 3 1 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 CDJ62075.1 - 0.28 9.9 52.3 0.79 8.4 16.1 3.3 3 0 0 3 3 3 0 Presenilin RAP1 PF07218.11 CDJ62075.1 - 5.3 5.2 8.8 9.2 4.4 8.8 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Utp14 PF04615.13 CDJ62075.1 - 9.7 4.6 47.8 5.7 5.4 4.3 2.2 2 0 0 2 2 2 0 Utp14 protein RRM_1 PF00076.22 CDJ62076.1 - 4.2e-08 32.9 0.1 6.7e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DAGAT PF03982.13 CDJ62076.1 - 0.086 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Diacylglycerol acyltransferase SID-1_RNA_chan PF13965.6 CDJ62077.1 - 4.4 5.6 8.4 2.5 6.4 1.4 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Utp14 PF04615.13 CDJ62077.1 - 5.9 5.3 45.7 8.3 4.9 45.7 1.3 1 0 0 1 1 1 0 Utp14 protein Methyltransf_32 PF13679.6 CDJ62078.1 - 9.4e-08 32.2 10.1 9.4e-08 32.2 10.1 2.8 2 0 0 2 2 2 1 Methyltransferase domain FmiP_Thoc5 PF09766.9 CDJ62078.1 - 5.9e-07 29.1 1.3 5.9e-07 29.1 1.3 2.3 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 DUF2722 PF10846.8 CDJ62078.1 - 0.00037 19.6 3.9 0.00037 19.6 3.9 2.8 3 1 0 3 3 2 2 Protein of unknown function (DUF2722) HNOBA PF07701.14 CDJ62078.1 - 0.0016 17.9 0.5 0.13 11.7 0.4 2.5 2 0 0 2 2 2 1 Heme NO binding associated FAM60A PF15396.6 CDJ62078.1 - 0.0061 16.6 7.4 1.1 9.3 3.4 3.4 3 0 0 3 3 3 1 Protein Family FAM60A MecA PF05389.12 CDJ62078.1 - 0.0075 15.9 8.0 0.072 12.7 3.2 2.8 2 0 0 2 2 2 1 Negative regulator of genetic competence (MecA) Pex14_N PF04695.13 CDJ62078.1 - 0.011 16.3 6.2 0.011 16.3 6.2 5.7 3 2 0 3 3 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4471 PF14740.6 CDJ62078.1 - 0.033 13.4 2.9 0.2 10.9 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) SpoIIP PF07454.11 CDJ62078.1 - 0.074 12.5 12.1 0.027 13.9 1.3 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) BORG_CEP PF14957.6 CDJ62078.1 - 0.19 12.9 15.1 0.67 11.1 1.0 3.6 3 0 0 3 3 3 0 Cdc42 effector PIP5K PF01504.18 CDJ62078.1 - 0.86 8.8 10.4 2.4 7.3 5.4 2.4 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase V_ATPase_I PF01496.19 CDJ62078.1 - 1.2 6.9 10.3 0.7 7.7 4.6 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family EOS1 PF12326.8 CDJ62078.1 - 1.3 8.9 7.1 47 3.9 0.2 2.8 2 1 0 2 2 1 0 N-glycosylation protein Peroxin-13_N PF04088.13 CDJ62078.1 - 2.4 8.4 15.7 2.5 8.4 1.8 4.3 4 0 0 4 4 4 0 Peroxin 13, N-terminal region Suf PF05843.14 CDJ62078.1 - 2.8 7.9 30.1 0.053 13.5 5.9 3.3 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Thg1C PF14413.6 CDJ62078.1 - 3.1 8.0 13.2 26 5.0 8.3 2.6 2 0 0 2 2 2 0 Thg1 C terminal domain DUF4770 PF15994.5 CDJ62078.1 - 3.6 7.8 19.7 0.12 12.6 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) SID-1_RNA_chan PF13965.6 CDJ62078.1 - 3.8 5.8 4.8 24 3.2 0.0 2.3 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 OATP PF03137.20 CDJ62078.1 - 5.4 5.2 5.9 3.8 5.7 1.2 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4667 PF15700.5 CDJ62078.1 - 9.9 6.2 31.1 0.22 11.6 4.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4667) Band_7 PF01145.25 CDJ62079.1 - 6.6e-22 78.4 0.2 1.2e-21 77.5 0.1 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family AAA_lid_4 PF17864.1 CDJ62079.1 - 0.053 13.3 0.9 0.14 11.9 0.0 2.1 2 1 0 2 2 2 0 RuvB AAA lid domain Rab3-GTPase_cat PF13890.6 CDJ62080.1 - 0.033 13.8 1.4 0.039 13.6 1.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit DUF3243 PF11588.8 CDJ62080.1 - 0.033 14.5 1.3 0.041 14.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) Apt1 PF10351.9 CDJ62081.1 - 1.2 7.9 4.6 1.5 7.6 4.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ62081.1 - 2.7 7.8 7.8 3.1 7.6 7.8 1.1 1 0 0 1 1 1 0 SPX domain RT_RNaseH_2 PF17919.1 CDJ62082.1 - 3.9e-25 87.8 0.0 7.8e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ62082.1 - 1.5e-23 83.1 0.0 4.4e-23 81.6 0.1 1.9 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ62082.1 - 1.1e-14 54.2 1.0 2.1e-14 53.4 1.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 CDJ62082.1 - 1.7e-09 37.6 0.0 3.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ62082.1 - 8.9e-09 35.9 0.0 2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ62082.1 - 2.8e-08 34.2 0.0 6.4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 CDJ62082.1 - 0.0037 17.4 0.3 0.0083 16.3 0.3 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease PF09668.10 CDJ62082.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 CDJ62082.1 - 0.03 13.8 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 CDJ62082.1 - 0.038 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF3552 PF12072.8 CDJ62082.1 - 0.087 12.2 0.8 0.14 11.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) rve PF00665.26 CDJ62083.1 - 1.8e-09 37.8 0.0 2.2e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 CDJ62084.1 - 3.3e-12 46.6 0.0 4.9e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ62084.1 - 0.049 13.4 0.7 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Integrase core domain Retrotrans_gag PF03732.17 CDJ62085.1 - 0.0075 16.5 0.0 0.036 14.3 0.0 2.1 3 0 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.11 CDJ62086.1 - 4.2e-09 36.3 0.0 7.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ62086.1 - 2.6e-08 34.4 0.0 6e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ62086.1 - 1.7e-07 31.7 0.0 4e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ62086.1 - 0.0082 16.4 0.0 0.037 14.3 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ62086.1 - 0.064 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF3552 PF12072.8 CDJ62086.1 - 0.24 10.8 0.2 0.37 10.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) RT_RNaseH_2 PF17919.1 CDJ62087.1 - 1.4e-29 102.0 0.0 2.5e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ62087.1 - 4.9e-29 100.7 0.0 1.3e-28 99.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ62087.1 - 4e-12 46.1 0.0 6.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ62087.1 - 0.022 14.8 1.8 0.022 14.8 1.8 1.8 2 0 0 2 2 2 0 Integrase zinc binding domain RVT_3 PF13456.6 CDJ62087.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like Chromo PF00385.24 CDJ62088.1 - 8.9e-13 47.9 0.0 2e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ribo_biogen_C PF04034.13 CDJ62089.1 - 1.2e-29 102.6 0.0 1.7e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal HSP70 PF00012.20 CDJ62090.1 - 3e-265 881.1 4.8 3.4e-265 880.9 4.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ62090.1 - 5.1e-15 55.1 0.2 9.1e-13 47.7 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CDJ62090.1 - 0.0034 17.1 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 CDJ62090.1 - 0.0034 16.7 0.2 0.0097 15.2 0.2 1.8 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase DDR PF08841.10 CDJ62090.1 - 0.0045 16.0 0.5 0.34 9.8 0.3 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain PKK PF12474.8 CDJ62090.1 - 0.2 11.8 8.0 0.3 11.2 3.5 2.2 2 0 0 2 2 2 0 Polo kinase kinase DUF4407 PF14362.6 CDJ62090.1 - 4.5 6.5 8.7 8.2 5.7 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF826 PF05696.11 CDJ62091.1 - 0.87 9.7 0.0 0.87 9.7 0.0 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF826) Pkinase PF00069.25 CDJ62092.1 - 0.051 12.9 0.0 0.051 12.9 0.0 2.8 3 0 0 3 3 3 0 Protein kinase domain Presenilin PF01080.17 CDJ62092.1 - 1 8.0 13.9 1.7 7.3 13.9 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 CDJ62092.1 - 5.4 5.4 9.2 7.8 4.8 9.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF72 PF01904.18 CDJ62093.1 - 0.1 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF72 Pkinase PF00069.25 CDJ62094.1 - 4.2e-11 42.7 0.1 3.8e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ62094.1 - 0.046 13.0 0.0 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 CDJ62095.1 - 5.4e-07 29.2 0.0 1.6e-05 24.4 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain PIP5K PF01504.18 CDJ62096.1 - 5.5e-48 163.6 0.0 9.1e-48 162.8 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_1 PF00036.32 CDJ62097.1 - 0.0024 17.3 0.1 0.005 16.3 0.1 1.6 1 0 0 1 1 1 1 EF hand LCD1 PF09798.9 CDJ62097.1 - 0.0045 15.6 6.2 0.0045 15.6 6.2 2.6 3 1 0 3 3 3 1 DNA damage checkpoint protein YL1 PF05764.13 CDJ62097.1 - 0.0086 16.2 23.9 0.0086 16.2 23.9 2.7 2 1 0 2 2 2 1 YL1 nuclear protein VIT1 PF01988.19 CDJ62097.1 - 0.011 15.6 4.9 0.011 15.6 4.9 2.8 2 1 0 2 2 2 0 VIT family EF-hand_6 PF13405.6 CDJ62097.1 - 0.032 14.2 0.4 0.099 12.6 0.4 1.8 1 0 0 1 1 1 0 EF-hand domain Apt1 PF10351.9 CDJ62097.1 - 0.033 13.0 28.3 0.12 11.3 17.2 2.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain EF-hand_7 PF13499.6 CDJ62097.1 - 0.053 14.0 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 CDJ62097.1 - 0.16 11.8 0.1 0.38 10.6 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair HSP70 PF00012.20 CDJ62098.1 - 1.8e-11 43.0 5.2 1.8e-11 43.0 5.2 5.7 5 1 1 6 6 6 3 Hsp70 protein SR-25 PF10500.9 CDJ62098.1 - 0.0007 19.3 10.2 0.0007 19.3 10.2 5.4 4 1 1 5 5 5 2 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 CDJ62098.1 - 0.0009 18.7 70.7 0.15 11.4 34.9 3.2 3 0 0 3 3 3 3 BUD22 SR-25 PF10500.9 CDJ62099.1 - 5.5e-05 22.9 8.5 5.5e-05 22.9 8.5 12.5 9 3 3 12 12 12 4 Nuclear RNA-splicing-associated protein zf-HC5HC2H_2 PF13832.6 CDJ62099.1 - 0.00026 21.1 7.8 0.00026 21.1 7.8 3.5 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDJ62099.1 - 0.00032 20.9 3.0 0.00032 20.9 3.0 4.5 4 1 0 4 4 4 2 PHD-like zinc-binding domain DUF755 PF05501.11 CDJ62099.1 - 0.0021 18.3 13.2 0.0021 18.3 13.2 16.0 15 2 0 15 15 15 2 Domain of unknown function (DUF755) DEAD PF00270.29 CDJ62101.1 - 1.6e-33 116.0 0.0 2.3e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3357 PF11837.8 CDJ62103.1 - 0.047 14.2 1.8 0.068 13.6 1.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF4175 PF13779.6 CDJ62103.1 - 8.1 4.2 35.5 10 3.9 35.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.13 CDJ62104.1 - 0.028 14.4 2.6 0.031 14.3 2.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1361 PF07099.11 CDJ62104.1 - 0.11 12.5 0.2 0.47 10.4 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1361) S36_mt PF10937.8 CDJ62104.1 - 0.2 13.3 0.1 0.2 13.3 0.1 1.9 1 1 1 2 2 2 0 Ribosomal protein S36, mitochondrial DUF4529 PF15032.6 CDJ62104.1 - 0.95 8.5 4.5 0.51 9.4 2.3 1.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4529) IMUP PF15761.5 CDJ62104.1 - 3.9 8.2 10.1 7.1 7.4 10.1 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF2681 PF10883.8 CDJ62104.1 - 6.8 7.2 11.9 12 6.4 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DREPP PF05558.12 CDJ62106.1 - 0.83 9.5 10.3 1 9.2 10.3 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Roughex PF06020.11 CDJ62106.1 - 1.8 7.6 16.6 1.8 7.6 16.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Androgen_recep PF02166.16 CDJ62106.1 - 5.7 5.7 22.1 6.3 5.5 22.1 1.2 1 0 0 1 1 1 0 Androgen receptor SMYLE_N PF18615.1 CDJ62106.1 - 8.4 5.8 18.7 9.7 5.6 18.7 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain MCM_bind PF09739.9 CDJ62106.1 - 8.5 4.7 22.5 9.7 4.5 22.5 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SLC12 PF03522.15 CDJ62107.1 - 0.35 9.8 12.2 0.5 9.3 12.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Nop14 PF04147.12 CDJ62107.1 - 0.64 8.2 36.1 0.88 7.7 36.1 1.1 1 0 0 1 1 1 0 Nop14-like family Helicase_C PF00271.31 CDJ62108.1 - 2.3e-29 102.0 0.0 4.2e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUIM_assoc PF16619.5 CDJ62108.1 - 0.0059 16.6 2.7 0.0079 16.2 2.7 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ62108.1 - 0.044 13.4 1.4 0.049 13.2 1.4 1.1 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ62108.1 - 0.63 9.2 3.3 0.75 8.9 3.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Patatin PF01734.22 CDJ62109.1 - 0.055 13.6 0.4 0.055 13.6 0.4 3.5 3 0 0 3 3 3 0 Patatin-like phospholipase Exonuc_VII_L PF02601.15 CDJ62111.1 - 1.1e-05 25.1 0.2 0.15 11.6 0.0 3.4 2 1 1 3 3 3 2 Exonuclease VII, large subunit Band_3_cyto PF07565.13 CDJ62111.1 - 0.09 12.6 0.5 0.83 9.4 0.1 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain HECT PF00632.25 CDJ62112.1 - 2.7e-48 165.0 0.0 4.9e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CDJ62112.1 - 0.0002 21.5 0.0 0.0002 21.5 0.0 3.0 3 0 0 3 3 3 1 SPRY domain Apt1 PF10351.9 CDJ62112.1 - 0.78 8.5 0.0 0.78 8.5 0.0 14.7 13 3 0 13 13 13 0 Golgi-body localisation protein domain TRAM_LAG1_CLN8 PF03798.16 CDJ62113.1 - 9e-08 32.1 12.5 1.2e-07 31.7 0.4 2.5 2 0 0 2 2 2 2 TLC domain HA2 PF04408.23 CDJ62114.1 - 3e-10 40.3 0.0 3e-10 40.3 0.0 4.7 5 1 0 5 5 5 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDJ62114.1 - 2.8e-09 37.3 0.0 1.6e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ62114.1 - 0.023 15.0 0.1 3.8 7.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain Borrelia_P83 PF05262.11 CDJ62114.1 - 2.3 6.6 30.5 0.031 12.8 22.7 1.8 2 0 0 2 2 2 0 Borrelia P83/100 protein HSP90 PF00183.18 CDJ62115.1 - 3.3e-108 362.8 0.0 1.2e-103 347.7 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CDJ62115.1 - 2.3e-10 40.4 0.0 4.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ62115.1 - 4.5e-09 36.8 0.2 9.4e-09 35.8 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2183 PF09949.9 CDJ62115.1 - 0.0057 17.0 0.2 4 7.8 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2183) Methyltransf_15 PF09445.10 CDJ62116.1 - 4.4e-09 36.1 0.0 9.7e-07 28.5 0.0 2.3 1 1 1 2 2 2 2 RNA cap guanine-N2 methyltransferase PAP2 PF01569.21 CDJ62117.1 - 0.012 15.4 1.1 0.88 9.3 0.7 2.1 1 1 1 2 2 2 0 PAP2 superfamily PXA PF02194.15 CDJ62117.1 - 0.11 12.5 0.6 0.15 12.0 0.6 1.2 1 0 0 1 1 1 0 PXA domain TFIIA PF03153.13 CDJ62117.1 - 0.22 11.5 15.8 0.26 11.2 15.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3474 PF11960.8 CDJ62117.1 - 1.2 9.3 4.4 0.44 10.7 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3474) RNA_pol_A_CTD PF03118.15 CDJ62118.1 - 0.0023 17.6 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain DnaJ_C PF01556.18 CDJ62119.1 - 1.4e-25 90.1 0.0 2.2e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ62119.1 - 1.4e-12 47.5 0.0 3.6e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 DnaJ domain Spt20 PF12090.8 CDJ62119.1 - 0.9 9.1 16.0 0.56 9.8 2.1 2.2 2 0 0 2 2 2 0 Spt20 family DUF3435 PF11917.8 CDJ62119.1 - 5.7 5.7 9.2 1 8.2 5.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) P120R PF08062.11 CDJ62120.1 - 0.086 13.2 13.7 2 8.9 3.0 2.9 2 0 0 2 2 2 0 P120R (NUC006) repeat PPP4R2 PF09184.11 CDJ62120.1 - 0.12 11.9 6.9 0.13 11.8 6.9 1.0 1 0 0 1 1 1 0 PPP4R2 Ndc1_Nup PF09531.10 CDJ62120.1 - 0.36 9.4 15.6 0.42 9.2 15.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Grg1 PF11034.8 CDJ62120.1 - 1.4 9.2 7.9 11 6.3 0.8 2.7 1 1 1 2 2 2 0 Glucose-repressible protein Grg1 LEA_3 PF03242.13 CDJ62120.1 - 1.7 9.4 12.6 3.3 8.5 2.3 2.2 1 1 1 2 2 2 0 Late embryogenesis abundant protein DUF4407 PF14362.6 CDJ62120.1 - 2 7.7 10.1 2.3 7.5 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med26_C PF15693.5 CDJ62120.1 - 2.8 8.1 13.8 3.8 7.6 13.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal Neur_chan_memb PF02932.16 CDJ62120.1 - 8.4 6.4 8.1 11 6.0 8.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LSM14 PF12701.7 CDJ62121.1 - 3.8e-26 91.0 0.0 6e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 CDJ62121.1 - 2.9e-05 24.1 0.0 6.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.13 CDJ62121.1 - 0.0018 18.4 4.1 0.0028 17.7 4.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ62121.1 - 0.0034 16.4 2.7 0.0045 16.0 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ62121.1 - 0.9 9.1 13.6 1.4 8.5 13.6 1.2 1 0 0 1 1 1 0 Spt20 family MSP1b PF03429.13 CDJ62121.1 - 1.3 7.1 10.1 1.8 6.6 10.1 1.1 1 0 0 1 1 1 0 Major surface protein 1B FDF PF09532.10 CDJ62121.1 - 1.5 9.8 9.0 0.31 11.9 0.9 2.4 2 0 0 2 2 2 0 FDF domain DUF4834 PF16118.5 CDJ62121.1 - 3.2 8.8 5.7 13 6.8 3.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) BRF1 PF07741.13 CDJ62121.1 - 4 7.8 5.8 29 5.1 0.1 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain RskA PF10099.9 CDJ62123.1 - 9.4e-06 26.0 4.2 9.4e-06 26.0 4.2 5.1 1 1 0 3 3 2 1 Anti-sigma-K factor rskA Gti1_Pac2 PF09729.9 CDJ62123.1 - 0.00088 19.4 6.7 0.27 11.3 5.9 2.4 2 1 0 2 2 2 1 Gti1/Pac2 family DUF4050 PF13259.6 CDJ62123.1 - 0.0018 18.6 4.1 0.12 12.7 0.7 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4050) PIP5K PF01504.18 CDJ62123.1 - 0.0035 16.6 5.1 0.75 9.0 5.9 2.2 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF908 PF06012.12 CDJ62123.1 - 0.0076 15.7 1.6 0.0076 15.7 1.6 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) CLN3 PF02487.17 CDJ62123.1 - 0.015 14.4 0.9 0.015 14.4 0.9 2.4 3 0 0 3 3 3 0 CLN3 protein SID-1_RNA_chan PF13965.6 CDJ62123.1 - 0.039 12.4 0.0 0.37 9.2 0.3 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 RPOL_N PF14700.6 CDJ62123.1 - 0.2 11.0 17.5 1.8 7.8 6.9 3.0 3 0 0 3 3 3 0 DNA-directed RNA polymerase N-terminal DUF4834 PF16118.5 CDJ62123.1 - 0.25 12.3 27.4 0.42 11.6 11.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) ABC2_membrane_2 PF12679.7 CDJ62123.1 - 0.32 10.2 6.1 1.1 8.5 2.3 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF4148 PF13663.6 CDJ62123.1 - 0.36 11.0 25.1 0.83 9.9 2.0 4.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Plasmodium_Vir PF05795.11 CDJ62123.1 - 0.61 9.4 2.1 3.3 7.0 0.5 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein MDM10 PF12519.8 CDJ62123.1 - 1.2 7.9 7.4 15 4.3 6.3 2.1 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 DUF4746 PF15928.5 CDJ62123.1 - 1.4 8.3 7.7 25 4.2 6.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CPSF100_C PF13299.6 CDJ62123.1 - 1.6 8.8 14.8 0.23 11.6 3.3 3.0 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 CDJ62123.1 - 2.1 8.1 15.1 0.024 14.4 3.1 2.6 3 0 0 3 3 3 0 Connexin EOS1 PF12326.8 CDJ62123.1 - 2.1 8.2 6.1 30 4.5 6.1 2.4 1 1 0 1 1 1 0 N-glycosylation protein DUF5327 PF17261.2 CDJ62123.1 - 3.7 8.3 29.2 7.1 7.4 11.7 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Ctr PF04145.15 CDJ62123.1 - 4.7 7.8 11.8 0.65 10.6 1.2 2.8 2 1 0 2 2 2 0 Ctr copper transporter family Eapp_C PF10238.9 CDJ62123.1 - 7.1 6.7 21.7 0.14 12.2 4.3 3.4 4 0 0 4 4 4 0 E2F-associated phosphoprotein RIC3 PF15361.6 CDJ62123.1 - 9.8 6.6 14.8 17 5.8 5.2 3.2 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 WD40 PF00400.32 CDJ62124.1 - 9.8e-08 32.6 11.3 9.5e-06 26.3 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1645 PF07816.11 CDJ62124.1 - 7.5e-05 23.4 12.2 0.017 15.7 0.7 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1645) TFIIA PF03153.13 CDJ62124.1 - 0.059 13.4 4.4 0.092 12.7 4.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ62124.1 - 0.11 12.1 4.1 0.19 11.3 4.1 1.3 1 0 0 1 1 1 0 Spt20 family Hira PF07569.11 CDJ62124.1 - 0.14 11.8 0.0 0.14 11.8 0.0 2.6 3 0 0 3 3 3 0 TUP1-like enhancer of split Hydrolase_4 PF12146.8 CDJ62124.1 - 0.52 9.5 4.9 0.076 12.3 0.9 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ribosomal_60s PF00428.19 CDJ62124.1 - 1 10.0 25.6 1.7 9.3 10.3 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF4549 PF15082.6 CDJ62125.1 - 0.16 11.8 0.1 0.47 10.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) TPR_4 PF07721.14 CDJ62128.1 - 0.019 15.5 0.6 0.57 11.0 0.5 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ62128.1 - 0.059 14.2 2.4 0.97 10.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Spore_coat_CotO PF14153.6 CDJ62129.1 - 9.5 6.1 14.9 9.8 6.1 14.9 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Kelch_5 PF13854.6 CDJ62130.1 - 3e-13 49.4 1.1 5.3e-07 29.5 0.1 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CDJ62130.1 - 1.6e-11 44.0 7.7 2.4e-05 24.3 0.1 5.1 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ62130.1 - 5.7e-09 35.6 0.8 0.00079 19.3 1.1 3.4 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CDJ62130.1 - 7.3e-09 35.6 5.6 3.1e-08 33.6 0.3 3.7 2 1 1 3 3 3 1 Kelch motif Kelch_1 PF01344.25 CDJ62130.1 - 6.1e-08 32.1 2.1 6.1e-08 32.1 2.1 4.0 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.6 CDJ62130.1 - 0.00034 20.8 12.6 0.0026 18.0 0.2 5.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Stathmin PF00836.19 CDJ62131.1 - 0.0028 17.6 16.1 0.0028 17.6 16.1 2.6 1 1 1 2 2 2 1 Stathmin family AATF-Che1 PF13339.6 CDJ62131.1 - 0.088 13.5 12.8 3.7 8.2 0.0 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor FlxA PF14282.6 CDJ62131.1 - 1.8 8.6 13.5 0.38 10.8 9.0 2.2 2 1 0 2 2 2 0 FlxA-like protein Ima1_N PF09779.9 CDJ62131.1 - 7.6 7.4 9.6 1.1 10.1 3.2 2.4 1 1 0 2 2 2 0 Ima1 N-terminal domain SR-25 PF10500.9 CDJ62133.1 - 0.00016 21.4 5.3 0.00016 21.4 5.3 2.4 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SNAPc_SNAP43 PF09808.9 CDJ62133.1 - 0.0002 21.4 0.7 0.014 15.4 0.0 3.0 3 0 0 3 3 3 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Eapp_C PF10238.9 CDJ62133.1 - 0.02 15.0 2.0 0.062 13.4 0.6 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein V_ATPase_I PF01496.19 CDJ62133.1 - 0.13 10.2 1.1 0.21 9.4 1.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ62133.1 - 0.14 11.9 0.2 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 Connexin DUF2722 PF10846.8 CDJ62133.1 - 0.29 10.0 20.0 0.46 9.4 14.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2722) Ribosomal_60s PF00428.19 CDJ62133.1 - 2.2 9.0 26.5 3.4 8.3 0.1 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Neur_chan_memb PF02932.16 CDJ62133.1 - 2.5 8.1 5.2 1.9 8.5 3.2 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Activator_LAG-3 PF11498.8 CDJ62133.1 - 3.8 6.4 25.2 0.77 8.7 17.7 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF3446 PF11928.8 CDJ62133.1 - 4.6 7.6 29.2 0.085 13.2 1.4 3.6 4 0 0 4 4 4 0 Early growth response N-terminal domain CDT1_C PF16679.5 CDJ62133.1 - 5.2 7.6 13.9 2.8 8.4 0.1 3.4 3 1 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain eIF-3_zeta PF05091.12 CDJ62133.1 - 6.1 5.7 8.1 9.9 5.0 8.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TCP PF03634.13 CDJ62133.1 - 8.9 6.9 16.2 0.057 14.0 4.2 2.6 3 0 0 3 3 3 0 TCP family transcription factor HEM4 PF02602.15 CDJ62134.1 - 2.5e-11 43.4 3.8 5.7e-06 25.8 4.0 4.5 4 3 0 5 5 5 2 Uroporphyrinogen-III synthase HemD PAT1 PF09770.9 CDJ62134.1 - 5.4 5.2 26.6 0.25 9.6 14.9 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TruD PF01142.18 CDJ62135.1 - 2.5e-48 164.9 0.0 6.6e-45 153.7 0.0 4.3 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) HEAT PF02985.22 CDJ62135.1 - 0.23 11.8 2.7 3 8.4 0.5 3.9 2 0 0 2 2 2 0 HEAT repeat TFIIA PF03153.13 CDJ62136.1 - 0.15 12.1 34.1 0.18 11.8 34.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNase PF00565.17 CDJ62137.1 - 1e-51 173.9 0.2 2.3e-14 53.8 0.0 4.9 5 0 0 5 5 5 4 Staphylococcal nuclease homologue TUDOR PF00567.24 CDJ62137.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Tudor domain Spt20 PF12090.8 CDJ62137.1 - 0.23 11.0 3.4 0.45 10.1 3.4 1.4 1 0 0 1 1 1 0 Spt20 family REF PF05755.12 CDJ62137.1 - 2.3 8.0 5.3 2.7 7.8 0.8 2.5 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) SUIM_assoc PF16619.5 CDJ62137.1 - 2.5 8.2 11.1 1.2 9.2 7.2 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 CDJ62142.1 - 0.0083 16.2 2.0 0.0083 16.2 2.0 3.2 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ62142.1 - 0.91 9.4 18.6 1.1 9.1 18.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_delta_4 PF04081.13 CDJ62143.1 - 3.5e-16 59.8 0.0 5.3e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 TPPII_N PF12583.8 CDJ62143.1 - 0.5 10.9 13.2 0.97 10.0 5.3 2.2 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal DUF4148 PF13663.6 CDJ62143.1 - 2.3 8.5 20.5 1.3 9.3 0.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) zf_CCCH_4 PF18345.1 CDJ62144.1 - 1.5e-06 28.0 1.3 4.4e-06 26.6 1.3 1.9 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CDJ62144.1 - 1.4e-05 25.7 0.0 3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 CDJ62144.1 - 2.1e-05 24.3 0.4 6.9e-05 22.6 0.4 2.0 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ62144.1 - 0.0023 17.7 0.8 0.0053 16.5 0.8 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger FYVE PF01363.21 CDJ62144.1 - 0.011 15.8 3.9 0.011 15.8 3.9 2.3 2 1 0 2 2 2 0 FYVE zinc finger Myb_Cef PF11831.8 CDJ62144.1 - 0.012 15.2 0.1 0.014 14.9 0.1 1.1 1 0 0 1 1 1 0 pre-mRNA splicing factor component Phostensin_N PF13916.6 CDJ62144.1 - 0.045 14.1 1.1 0.71 10.3 1.2 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal zf-CCCH_2 PF14608.6 CDJ62144.1 - 0.58 10.7 4.3 0.24 11.9 0.8 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger AAA PF00004.29 CDJ62145.1 - 3e-11 43.8 4.6 1e-08 35.7 0.6 3.7 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ62145.1 - 0.00012 22.4 7.3 0.0096 16.2 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_19 PF13245.6 CDJ62145.1 - 0.00016 22.1 0.5 0.00062 20.1 0.1 2.2 2 1 0 2 2 2 1 AAA domain Spt20 PF12090.8 CDJ62145.1 - 0.0012 18.5 6.5 0.0012 18.5 6.5 2.6 2 1 0 2 2 1 1 Spt20 family Med15 PF09606.10 CDJ62145.1 - 0.0014 17.4 37.2 0.002 17.0 37.2 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_16 PF13191.6 CDJ62145.1 - 0.0015 18.9 7.8 0.0015 18.9 7.8 2.6 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CDJ62145.1 - 0.0027 17.5 0.0 0.02 14.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ62145.1 - 0.0031 17.5 0.5 0.015 15.3 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TFIIA PF03153.13 CDJ62145.1 - 0.0058 16.7 9.7 0.0058 16.7 9.7 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PhoH PF02562.16 CDJ62145.1 - 0.0063 16.0 0.0 0.34 10.3 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 CDJ62145.1 - 0.0083 15.9 2.7 0.0083 15.9 2.7 2.9 2 1 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 CDJ62145.1 - 0.02 14.7 0.0 0.054 13.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein Mg_chelatase PF01078.21 CDJ62145.1 - 0.022 14.1 0.6 0.063 12.7 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDJ62145.1 - 0.031 14.7 0.4 0.076 13.4 0.0 1.9 2 0 0 2 2 1 0 RNA helicase IstB_IS21 PF01695.17 CDJ62145.1 - 0.032 13.9 0.0 0.032 13.9 0.0 2.2 3 0 0 3 3 2 0 IstB-like ATP binding protein Lin-8 PF03353.15 CDJ62145.1 - 0.052 13.1 11.3 0.062 12.9 2.2 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist AAA_24 PF13479.6 CDJ62145.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.2 3 1 1 4 4 2 0 AAA domain AAA_14 PF13173.6 CDJ62145.1 - 0.16 12.0 0.3 4.5 7.3 0.0 2.9 3 1 1 4 4 3 0 AAA domain EPL1 PF10513.9 CDJ62145.1 - 0.22 11.9 9.8 2.7 8.3 3.3 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like ResIII PF04851.15 CDJ62145.1 - 0.23 11.5 0.0 0.23 11.5 0.0 3.0 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 CDJ62145.1 - 0.24 12.0 0.3 0.9 10.1 0.0 2.1 3 0 0 3 3 2 0 AAA domain Gti1_Pac2 PF09729.9 CDJ62145.1 - 0.51 10.4 4.5 11 6.1 2.0 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family Sin_N PF04801.13 CDJ62145.1 - 0.75 8.9 22.4 0.32 10.2 12.0 2.2 2 0 0 2 2 2 0 Sin-like protein conserved region Rtf2 PF04641.12 CDJ62145.1 - 0.81 9.0 15.4 0.045 13.1 0.5 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger MH2 PF03166.14 CDJ62145.1 - 0.87 9.8 4.4 2.8 8.1 1.0 2.3 2 0 0 2 2 2 0 MH2 domain FAM60A PF15396.6 CDJ62145.1 - 1.3 9.0 6.0 15 5.5 2.6 2.1 2 0 0 2 2 2 0 Protein Family FAM60A CLN3 PF02487.17 CDJ62145.1 - 2.3 7.2 8.4 2 7.3 3.8 2.0 2 0 0 2 2 2 0 CLN3 protein EIIBC-GUT_N PF03612.14 CDJ62145.1 - 2.3 7.9 9.6 10 5.8 4.3 2.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus ORC_WH_C PF18137.1 CDJ62145.1 - 3.3 7.8 12.1 2 8.5 0.3 2.4 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal NACHT PF05729.12 CDJ62145.1 - 4.2 7.3 9.6 1.6 8.7 0.1 3.3 3 1 0 3 3 3 0 NACHT domain AAA_2 PF07724.14 CDJ62145.1 - 7.2 6.7 0.0 7.2 6.7 0.0 3.9 3 2 0 4 4 3 0 AAA domain (Cdc48 subfamily) Mit_KHE1 PF10173.9 CDJ62145.1 - 7.4 6.6 8.3 5.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF3464 PF11947.8 CDJ62145.1 - 7.7 6.3 11.8 5.1 6.8 0.2 2.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 AFG1_ATPase PF03969.16 CDJ62145.1 - 8.4 5.2 10.9 0.33 9.8 4.5 2.1 2 1 0 2 2 2 0 AFG1-like ATPase Folliculin PF11704.8 CDJ62145.1 - 9.2 6.1 12.7 17 5.3 0.3 2.4 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport AAA PF00004.29 CDJ62147.1 - 2.8e-45 154.0 0.0 8.4e-45 152.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ62147.1 - 5e-19 67.8 7.6 8.2e-11 41.5 0.1 3.1 3 0 0 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 CDJ62147.1 - 0.00025 20.8 0.0 0.00082 19.2 0.0 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain SUIM_assoc PF16619.5 CDJ62147.1 - 0.001 19.1 37.1 0.091 12.8 1.5 3.6 3 0 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 TIP49 PF06068.13 CDJ62147.1 - 0.0033 16.7 0.0 0.0061 15.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 CDJ62147.1 - 0.0059 16.8 0.1 0.12 12.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Spt20 PF12090.8 CDJ62147.1 - 0.0075 15.9 36.7 0.071 12.7 4.7 3.1 3 0 0 3 3 3 3 Spt20 family NCA2 PF08637.10 CDJ62147.1 - 0.012 14.8 3.0 0.055 12.6 0.3 2.1 2 0 0 2 2 2 0 ATP synthase regulation protein NCA2 AAA_5 PF07728.14 CDJ62147.1 - 0.019 15.0 0.0 0.098 12.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ62147.1 - 0.2 12.1 0.0 0.2 12.1 0.0 4.6 3 2 1 4 4 3 0 AAA ATPase domain Bro-N PF02498.17 CDJ62147.1 - 0.22 12.3 0.8 3 8.6 0.0 2.4 2 1 0 2 2 2 0 BRO family, N-terminal domain AAA_33 PF13671.6 CDJ62147.1 - 0.46 10.7 0.0 0.46 10.7 0.0 3.5 3 2 0 3 3 3 0 AAA domain DUF2722 PF10846.8 CDJ62147.1 - 0.46 9.4 29.0 0.033 13.1 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Adeno_PIX PF03955.14 CDJ62147.1 - 0.57 10.4 6.5 0.99 9.6 3.6 2.4 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) AAA_22 PF13401.6 CDJ62147.1 - 6.7 7.0 6.8 4.4 7.6 0.0 3.4 3 1 1 4 4 4 0 AAA domain SR-25 PF10500.9 CDJ62148.1 - 0.014 15.0 8.5 0.018 14.7 8.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4692 PF15763.5 CDJ62148.1 - 0.024 15.1 2.0 0.035 14.6 2.0 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF1645 PF07816.11 CDJ62148.1 - 0.16 12.6 5.9 0.23 12.0 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DUF755 PF05501.11 CDJ62148.1 - 0.61 10.4 11.8 0.98 9.7 11.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Syntaphilin PF15290.6 CDJ62148.1 - 3.3 7.3 6.1 5.1 6.6 6.1 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Gar1 PF04410.14 CDJ62149.1 - 1.2e-17 64.1 0.0 7e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region DUF1635 PF07795.11 CDJ62150.1 - 0.044 13.6 0.2 0.044 13.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) UPF0449 PF15136.6 CDJ62150.1 - 0.83 10.2 5.7 1.2 9.7 4.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF966 PF06136.13 CDJ62150.1 - 6 6.5 10.3 2.2 7.9 7.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF966) TRAP_alpha PF03896.16 CDJ62151.1 - 3.7 6.7 6.1 3 7.0 2.7 2.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit AP2 PF00847.20 CDJ62152.1 - 1.1e-08 35.1 0.2 1.1e-08 35.1 0.2 2.3 2 0 0 2 2 2 1 AP2 domain Ribosomal_L14 PF00238.19 CDJ62153.1 - 1.5e-17 63.8 0.0 2.2e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SUIM_assoc PF16619.5 CDJ62153.1 - 0.0051 16.8 1.6 0.016 15.2 1.6 1.9 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ62153.1 - 5.7 7.2 19.0 0.87 9.9 14.1 2.0 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Med3 PF11593.8 CDJ62153.1 - 6 5.9 13.9 0.68 9.1 2.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal AAA_23 PF13476.6 CDJ62155.1 - 4.8 7.6 32.8 1.1 9.7 14.6 3.4 3 1 0 3 3 3 0 AAA domain DUF5134 PF17197.4 CDJ62155.1 - 9.6 6.1 31.6 1.1 9.2 9.8 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5134) ATP-grasp_2 PF08442.10 CDJ62157.1 - 2.5e-56 190.5 2.7 1.2e-54 185.0 0.6 2.7 2 1 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 CDJ62157.1 - 2.2e-15 56.8 0.3 2.2e-15 56.8 0.3 2.6 3 0 0 3 3 2 1 CoA-ligase SUIM_assoc PF16619.5 CDJ62157.1 - 2.6e-07 30.6 26.2 6.4e-05 22.9 0.0 4.7 4 1 1 5 5 4 1 Unstructured region C-term to UIM in Ataxin3 ATP-grasp_5 PF13549.6 CDJ62157.1 - 3.1e-07 30.1 0.5 8.3e-06 25.4 0.5 2.4 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CDJ62157.1 - 0.0065 16.1 1.3 0.3 10.7 0.0 2.6 1 1 1 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.19 CDJ62157.1 - 0.037 13.8 0.8 0.2 11.4 0.1 2.6 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain dsRBD2 PF17842.1 CDJ62157.1 - 0.075 13.2 1.7 0.61 10.3 0.1 2.8 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 RNA_pol_Rbc25 PF08292.12 CDJ62157.1 - 0.28 11.4 3.9 2.4 8.4 0.6 2.6 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Ndc1_Nup PF09531.10 CDJ62157.1 - 0.42 9.2 6.3 0.5 9.0 0.2 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 CDJ62157.1 - 0.72 9.8 13.0 3.7 7.5 5.7 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4407 PF14362.6 CDJ62157.1 - 1.1 8.5 22.5 0.96 8.7 7.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ62157.1 - 1.9 8.4 46.5 0.076 13.0 7.7 2.6 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ62158.1 - 0.0012 17.5 25.1 0.0012 17.5 25.1 3.0 2 1 0 2 2 2 1 Macoilin family YtxH PF12732.7 CDJ62158.1 - 0.011 16.3 3.0 0.011 16.3 3.0 3.7 3 0 0 3 3 3 0 YtxH-like protein OmpH PF03938.14 CDJ62158.1 - 2.9 8.2 22.1 0.77 10.1 2.7 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 CDJ62158.1 - 6.9 6.1 17.6 2.2 7.8 2.5 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Serglycin PF04360.12 CDJ62159.1 - 0.013 15.5 2.5 0.023 14.7 2.5 1.3 1 0 0 1 1 1 0 Serglycin DUF4710 PF15828.5 CDJ62159.1 - 0.02 15.0 4.5 0.032 14.3 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) CCDC106 PF15794.5 CDJ62159.1 - 0.56 9.9 5.9 0.83 9.3 5.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 tRNA-synt_2 PF00152.20 CDJ62160.1 - 6.5e-72 242.3 0.4 6.5e-72 242.3 0.4 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ62160.1 - 5.2e-06 26.3 0.0 9.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDJ62160.1 - 0.00071 19.1 0.1 0.53 9.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SUIM_assoc PF16619.5 CDJ62160.1 - 0.017 15.2 3.0 0.017 15.2 3.0 5.6 4 2 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Pox_A12 PF04651.13 CDJ62160.1 - 0.067 13.2 0.1 0.067 13.2 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A12 protein Herpes_pp85 PF04637.12 CDJ62160.1 - 2.9 6.2 13.2 1.2 7.5 2.5 2.3 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Spt20 PF12090.8 CDJ62160.1 - 3 7.4 53.3 1.1 8.9 6.7 3.3 3 0 0 3 3 3 0 Spt20 family HEAT PF02985.22 CDJ62162.1 - 0.0015 18.6 6.6 0.76 10.2 0.1 6.3 4 0 0 4 4 4 2 HEAT repeat Cohesin_HEAT PF12765.7 CDJ62162.1 - 0.026 14.8 0.8 0.7 10.2 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DOR PF14839.6 CDJ62163.1 - 1.8 8.5 13.0 2.3 8.1 13.0 1.2 1 0 0 1 1 1 0 DOR family tRNA-synt_2 PF00152.20 CDJ62165.1 - 1.5e-82 277.2 0.0 1.8e-82 276.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ62165.1 - 5.8e-10 39.0 0.1 1.8e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDJ62165.1 - 0.00036 20.1 0.1 0.0029 17.1 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Pdase_M17_N2 PF18295.1 CDJ62168.1 - 0.028 14.7 0.4 0.028 14.7 0.4 3.2 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 PA26 PF04636.13 CDJ62168.1 - 5.9 5.7 10.7 12 4.7 0.1 2.3 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Ank_4 PF13637.6 CDJ62169.1 - 1.1e-05 25.9 0.0 0.00042 20.8 0.0 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ62169.1 - 5e-05 23.4 0.6 0.16 12.6 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 CDJ62169.1 - 0.00053 20.5 2.7 0.00076 20.0 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ62169.1 - 0.0086 16.4 0.0 0.04 14.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CDJ62169.1 - 0.029 14.8 7.8 0.1 13.1 0.1 4.5 5 0 0 5 5 5 0 Ankyrin repeat Methyltransf_25 PF13649.6 CDJ62169.1 - 0.14 12.8 0.1 1.2 9.9 0.0 2.6 3 1 0 3 3 3 0 Methyltransferase domain DENN PF02141.21 CDJ62171.1 - 2.6e-23 82.9 10.5 1.6e-19 70.6 7.7 2.7 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 CDJ62171.1 - 5.3e-05 23.9 5.0 0.0015 19.2 0.1 3.4 3 0 0 3 3 3 2 uDENN domain Aminotran_1_2 PF00155.21 CDJ62172.1 - 0.16 11.1 0.6 1.1 8.4 0.1 2.4 1 1 1 2 2 2 0 Aminotransferase class I and II RRM_1 PF00076.22 CDJ62173.1 - 1e-15 57.3 0.1 1.6e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 CDJ62173.1 - 9.7e-11 41.8 0.0 4e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 SPOC domain RRM_occluded PF16842.5 CDJ62173.1 - 0.035 14.0 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif SET_assoc PF11767.8 CDJ62173.1 - 0.052 13.2 0.2 0.093 12.4 0.2 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 CDJ62173.1 - 0.085 12.9 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 RNA binding motif Methyltransf_11 PF08241.12 CDJ62174.1 - 1.9e-14 54.1 0.6 8.3e-13 48.8 0.3 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ62174.1 - 2.6e-12 47.3 0.6 1.9e-10 41.3 0.4 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ62174.1 - 3.7e-06 26.8 0.0 3.7e-06 26.8 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ62174.1 - 0.00015 22.5 0.1 0.00015 22.5 0.1 2.9 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ62174.1 - 0.00051 19.9 1.7 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ62174.1 - 0.035 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 CDJ62174.1 - 0.091 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FNIP_N PF14636.6 CDJ62174.1 - 2.5 9.1 9.7 4.1 8.4 9.7 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus SpoIIP PF07454.11 CDJ62174.1 - 3.3 7.1 6.9 4.2 6.7 6.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4192 PF13830.6 CDJ62174.1 - 6.4 6.7 8.6 9.7 6.1 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) zf-DNL PF05180.12 CDJ62176.1 - 1.3e-27 95.5 0.4 2.1e-27 94.9 0.4 1.3 1 0 0 1 1 1 1 DNL zinc finger CGGC PF08821.11 CDJ62176.1 - 0.54 10.5 3.5 0.5 10.6 2.0 1.8 1 1 1 2 2 2 0 CGGC domain DUF3458_C PF17432.2 CDJ62177.1 - 7.4e-99 331.1 6.0 1.3e-98 330.3 6.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 CDJ62177.1 - 4.3e-48 163.7 0.1 7.4e-48 163.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 CDJ62177.1 - 2.3e-23 82.4 0.1 5.1e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 CDJ62177.1 - 3.2e-12 47.0 0.0 5.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 CDJ62177.1 - 0.088 13.2 0.1 0.39 11.1 0.1 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase cNMP_binding PF00027.29 CDJ62179.1 - 1.1e-21 76.7 0.0 1.6e-10 40.9 0.0 3.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Spc7 PF08317.11 CDJ62179.1 - 0.14 11.0 26.1 0.0037 16.2 18.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 CDJ62179.1 - 0.55 8.8 16.2 1.1 7.8 16.2 1.4 1 0 0 1 1 1 0 AAA domain Bacillus_HBL PF05791.11 CDJ62179.1 - 3.4 7.5 9.0 2.4 8.0 3.4 2.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FliD_C PF07195.12 CDJ62179.1 - 3.7 6.9 7.5 0.97 8.8 1.1 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus ClpS PF02617.17 CDJ62180.1 - 1.3e-11 44.1 0.1 1.9e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Pterin_bind PF00809.22 CDJ62181.1 - 3.5e-73 246.3 0.3 5.8e-73 245.6 0.3 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 CDJ62181.1 - 1e-24 87.2 0.0 2.6e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF3560 PF12083.8 CDJ62181.1 - 0.12 12.6 0.1 0.58 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) Peptidase_A21 PF03566.13 CDJ62182.1 - 0.0068 14.7 0.2 0.0084 14.4 0.2 1.1 1 0 0 1 1 1 1 Peptidase family A21 CAP PF00188.26 CDJ62182.1 - 0.025 15.4 1.5 0.038 14.8 1.5 1.4 1 1 0 1 1 1 0 Cysteine-rich secretory protein family Miff PF05644.11 CDJ62182.1 - 0.12 11.9 0.5 0.14 11.8 0.5 1.3 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff CAP PF00188.26 CDJ62183.1 - 0.0073 17.1 1.5 0.013 16.4 1.5 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ62184.1 - 0.038 14.8 0.3 0.062 14.1 0.3 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ62185.1 - 0.036 14.9 1.2 0.064 14.1 1.2 1.5 1 1 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ62186.1 - 0.0028 18.5 1.9 0.005 17.7 1.7 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Aida_C2 PF14186.6 CDJ62189.1 - 0.06 13.0 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal adhesion Calci_bind_CcbP PF11535.8 CDJ62189.1 - 0.19 12.3 0.2 0.53 10.8 0.1 1.7 2 0 0 2 2 2 0 Calcium binding AIMP2_LysRS_bd PF16780.5 CDJ62190.1 - 0.14 11.9 0.1 0.33 10.7 0.1 1.6 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain CAP PF00188.26 CDJ62191.1 - 0.00014 22.7 0.1 0.00021 22.1 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF2228 PF10228.9 CDJ62191.1 - 0.16 11.7 0.1 0.21 11.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) CAP PF00188.26 CDJ62193.1 - 0.026 15.4 0.1 0.043 14.7 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family VAPB_antitox PF02697.14 CDJ62194.1 - 0.049 14.4 0.0 10 7.0 0.1 2.7 3 0 0 3 3 3 0 Putative antitoxin CAP PF00188.26 CDJ62195.1 - 0.0025 18.6 0.1 0.0035 18.2 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF3944 PF13099.6 CDJ62195.1 - 0.14 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) CAP PF00188.26 CDJ62196.1 - 0.11 13.4 0.1 0.14 13.0 0.1 1.3 1 0 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ62197.1 - 0.056 14.3 0.1 0.078 13.8 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family tRNA-synt_1 PF00133.22 CDJ62200.1 - 4.1e-29 101.3 0.0 1.8e-06 26.5 0.0 4.8 4 1 0 4 4 4 4 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ62200.1 - 4.4e-16 59.2 0.0 1.6e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ62200.1 - 2.4e-14 52.9 0.0 3.3e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CDJ62200.1 - 2.8e-09 36.8 0.0 7.2e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF2722 PF10846.8 CDJ62200.1 - 5.6 5.8 10.1 0.24 10.3 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ62200.1 - 6.7 6.6 12.1 3.5 7.5 5.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF5400 PF17379.2 CDJ62201.1 - 0.0012 19.3 3.7 0.0023 18.4 3.7 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5400) DUF2070 PF09843.9 CDJ62201.1 - 0.24 9.6 7.6 0.35 9.1 7.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Tetraspanin PF00335.20 CDJ62201.1 - 3 7.5 10.0 6 6.5 10.0 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF2207 PF09972.9 CDJ62201.1 - 4.6 5.9 7.4 1.2 7.8 2.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) FKBP_C PF00254.28 CDJ62202.1 - 1.8e-19 69.8 0.0 3.8e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Roughex PF06020.11 CDJ62202.1 - 0.011 14.8 4.7 0.011 14.8 4.7 3.1 2 1 1 3 3 3 0 Drosophila roughex protein RPA43_OB PF17875.1 CDJ62202.1 - 0.44 11.2 0.1 0.44 11.2 0.1 3.1 2 1 0 2 2 2 0 RPA43 OB domain in RNA Pol I Activator_LAG-3 PF11498.8 CDJ62202.1 - 1.3 7.9 67.9 0.27 10.2 34.6 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SLC12 PF03522.15 CDJ62202.1 - 2.4 7.1 17.7 1.9 7.4 0.3 2.1 2 0 0 2 2 2 0 Solute carrier family 12 eIF-3_zeta PF05091.12 CDJ62202.1 - 2.4 7.0 22.6 1.9 7.4 3.4 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 CDJ62202.1 - 4.1 7.3 31.9 2.3 8.1 6.1 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DcuC PF03606.15 CDJ62202.1 - 4.4 5.7 5.8 0.35 9.3 0.1 1.9 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier MAT1 PF06391.13 CDJ62202.1 - 5.1 6.9 34.7 3.9 7.2 19.6 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 TFIIA PF03153.13 CDJ62203.1 - 0.058 13.4 39.5 0.066 13.2 39.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SWI-SNF_Ssr4 PF08549.10 CDJ62203.1 - 0.069 11.8 14.9 0.079 11.6 14.9 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) ASD2 PF08687.11 CDJ62203.1 - 0.26 10.8 16.6 0.32 10.5 16.6 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 SMYLE_N PF18615.1 CDJ62203.1 - 0.27 10.8 9.0 0.31 10.6 9.0 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Hamartin PF04388.12 CDJ62203.1 - 0.27 9.8 13.3 0.31 9.7 13.3 1.0 1 0 0 1 1 1 0 Hamartin protein DUF789 PF05623.12 CDJ62203.1 - 0.39 10.4 9.6 0.4 10.3 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Neuregulin PF02158.15 CDJ62203.1 - 0.47 9.8 16.3 0.57 9.5 16.3 1.1 1 0 0 1 1 1 0 Neuregulin intracellular region Velvet PF11754.8 CDJ62203.1 - 0.48 10.3 13.9 0.57 10.1 13.9 1.1 1 0 0 1 1 1 0 Velvet factor DUF2052 PF09747.9 CDJ62203.1 - 0.65 10.1 17.5 0.8 9.8 17.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CLN3 PF02487.17 CDJ62203.1 - 1.2 8.1 7.0 1.5 7.8 7.0 1.2 1 0 0 1 1 1 0 CLN3 protein Med15 PF09606.10 CDJ62203.1 - 2 7.0 34.5 2.4 6.7 34.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal VIR_N PF15912.5 CDJ62203.1 - 2.1 7.9 12.2 2.6 7.6 12.2 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal FAM60A PF15396.6 CDJ62203.1 - 2.4 8.1 12.3 2.8 7.9 12.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 CDJ62203.1 - 2.5 6.8 21.6 3.1 6.5 21.6 1.0 1 0 0 1 1 1 0 Presenilin RPN2_C PF18004.1 CDJ62203.1 - 2.5 8.0 16.1 3.1 7.7 16.1 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Endostatin PF06482.11 CDJ62203.1 - 2.6 7.4 15.0 3.1 7.2 15.0 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Med13_C PF06333.12 CDJ62203.1 - 3.2 6.9 12.1 3.5 6.8 12.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain PA26 PF04636.13 CDJ62203.1 - 3.2 6.6 9.4 3.8 6.3 9.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Raftlin PF15250.6 CDJ62203.1 - 3.4 6.3 12.8 3.8 6.1 12.8 1.0 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.13 CDJ62203.1 - 3.5 6.3 13.6 4 6.1 13.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CCSAP PF15748.5 CDJ62203.1 - 3.8 7.6 21.0 4.6 7.3 21.0 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4551 PF15087.6 CDJ62203.1 - 4.8 5.9 15.2 5.7 5.6 15.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pannexin_like PF12534.8 CDJ62203.1 - 5 6.1 9.1 6.5 5.7 9.1 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Suf PF05843.14 CDJ62203.1 - 5 7.0 22.7 5.9 6.8 22.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PPL5 PF18168.1 CDJ62203.1 - 5.2 6.3 10.2 6.3 6.0 10.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 MMR1 PF08505.10 CDJ62203.1 - 5.2 7.3 17.9 7.9 6.7 17.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Tim54 PF11711.8 CDJ62203.1 - 5.3 5.7 15.2 6.1 5.5 15.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 CDJ62203.1 - 7 6.6 14.9 8.1 6.4 14.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 CDJ62203.1 - 7.1 4.6 17.1 7.8 4.5 17.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 CDJ62203.1 - 7.4 5.7 10.9 8.5 5.5 10.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 CDJ62203.1 - 7.7 5.3 8.4 9 5.1 8.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CDC45 PF02724.14 CDJ62203.1 - 8.1 4.6 15.5 9.2 4.4 15.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 CDJ62206.1 - 1.3e-42 146.1 135.5 5.1e-26 91.3 8.2 4.7 2 1 1 3 3 3 3 Mpp10 protein Bestrophin PF01062.21 CDJ62207.1 - 0.17 11.2 5.0 0.48 9.8 5.0 1.7 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DDHD PF02862.17 CDJ62208.1 - 3.3e-31 109.2 8.5 3.3e-31 109.2 8.5 4.3 2 2 0 2 2 2 1 DDHD domain Spt20 PF12090.8 CDJ62208.1 - 0.29 10.7 22.1 1.5 8.4 8.6 2.6 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 CDJ62208.1 - 6.1 7.0 34.6 0.17 12.0 7.9 4.8 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 AAA_29 PF13555.6 CDJ62209.1 - 0.0063 16.2 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.20 CDJ62209.1 - 0.0074 15.5 0.0 0.0083 15.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Roc PF08477.13 CDJ62209.1 - 0.0078 16.4 0.0 0.0097 16.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Phage-A118_gp45 PF10653.9 CDJ62209.1 - 0.023 14.7 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein gp45 of Bacteriophage A118 AAA_7 PF12775.7 CDJ62209.1 - 0.028 13.9 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 CDJ62209.1 - 0.048 13.1 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 CDJ62209.1 - 0.062 13.0 0.1 0.076 12.8 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 CDJ62209.1 - 0.096 13.2 0.0 0.14 12.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 CDJ62209.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain SLATT_1 PF18181.1 CDJ62211.1 - 1.1 9.2 4.1 6.6 6.7 2.1 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 RskA PF10099.9 CDJ62211.1 - 4.7 7.5 12.6 11 6.3 12.6 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF1664 PF07889.12 CDJ62212.1 - 0.21 11.6 8.5 2.1 8.4 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Prominin PF05478.11 CDJ62212.1 - 3.8 5.3 8.8 1.7 6.5 4.4 2.0 2 0 0 2 2 2 0 Prominin Apolipoprotein PF01442.18 CDJ62212.1 - 3.8 7.3 50.2 16 5.3 28.8 3.6 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 CDJ62212.1 - 4.9 7.3 12.2 3.5 7.8 7.3 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family IF4E PF01652.18 CDJ62213.1 - 5.1e-14 52.4 0.0 8.5e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PS_Dcarbxylase PF02666.15 CDJ62216.1 - 2.1e-06 27.5 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Collagen PF01391.18 CDJ62218.1 - 0.0037 17.0 14.1 0.0037 17.0 14.1 3.3 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) AP2 PF00847.20 CDJ62218.1 - 0.014 15.6 1.1 0.05 13.8 1.1 2.0 1 0 0 1 1 1 0 AP2 domain DUF3273 PF11677.8 CDJ62220.1 - 4.9e-65 219.5 9.1 5.8e-65 219.2 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) SUIM_assoc PF16619.5 CDJ62221.1 - 0.076 13.1 11.5 3.5 7.8 0.2 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ62221.1 - 2.8 8.2 57.9 0.024 14.9 3.8 4.3 3 1 1 4 4 4 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ62223.1 - 0.0036 17.6 0.4 0.0044 17.3 0.4 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA UPF0239 PF06783.11 CDJ62223.1 - 0.049 13.8 5.3 0.49 10.6 2.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) MscL PF01741.18 CDJ62223.1 - 0.2 12.0 0.0 0.24 11.7 0.0 1.1 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL TFIIA PF03153.13 CDJ62223.1 - 0.41 10.6 22.1 0.51 10.3 22.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 CDJ62223.1 - 0.98 9.1 10.3 2.3 7.9 10.3 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LEAP-2 PF07359.11 CDJ62223.1 - 1.3 8.9 9.4 5.5 6.9 9.4 2.1 1 1 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Conotoxin PF02950.17 CDJ62223.1 - 4.5 8.4 12.3 0.18 12.9 4.0 2.5 2 1 0 2 2 2 0 Conotoxin PPP4R2 PF09184.11 CDJ62223.1 - 5.1 6.6 12.8 7 6.1 12.8 1.2 1 0 0 1 1 1 0 PPP4R2 DivIC PF04977.15 CDJ62223.1 - 8.6 6.2 15.5 11 5.9 15.5 1.2 1 0 0 1 1 1 0 Septum formation initiator EphA2_TM PF14575.6 CDJ62223.1 - 9 7.3 7.9 3.4 8.6 4.1 2.1 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RepB_primase PF16793.5 CDJ62225.1 - 0.05 13.7 13.1 0.09 12.9 13.1 1.4 1 0 0 1 1 1 0 RepB DNA-primase from phage plasmid FUSC PF04632.12 CDJ62225.1 - 1.5 7.2 15.9 1.8 7.0 15.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ndc1_Nup PF09531.10 CDJ62225.1 - 7.3 5.2 12.0 0.055 12.1 4.3 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup TFIIF_alpha PF05793.12 CDJ62226.1 - 0.0016 17.1 17.3 0.0019 16.9 17.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Draxin PF15550.6 CDJ62226.1 - 0.0051 16.7 12.0 0.0065 16.4 12.0 1.3 1 0 0 1 1 1 1 Draxin FAM60A PF15396.6 CDJ62226.1 - 0.0093 16.0 13.8 0.0093 16.0 13.8 2.1 2 0 0 2 2 1 1 Protein Family FAM60A SWIRM-assoc_2 PF16496.5 CDJ62226.1 - 0.016 14.1 11.4 0.019 13.9 11.4 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Apt1 PF10351.9 CDJ62226.1 - 0.079 11.8 13.9 0.088 11.7 13.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1168 PF06658.12 CDJ62226.1 - 0.086 12.6 22.0 0.18 11.6 22.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CDC45 PF02724.14 CDJ62226.1 - 0.1 10.9 8.4 0.12 10.7 8.4 1.2 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 CDJ62226.1 - 0.16 9.0 14.3 0.18 8.9 14.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4603 PF15376.6 CDJ62226.1 - 0.21 8.9 14.6 0.23 8.8 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF572 PF04502.13 CDJ62226.1 - 0.27 10.8 17.2 0.33 10.5 17.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Presenilin PF01080.17 CDJ62226.1 - 0.33 9.7 11.9 0.39 9.4 11.9 1.2 1 0 0 1 1 1 0 Presenilin GEMIN8 PF15348.6 CDJ62226.1 - 0.37 11.0 11.2 0.53 10.5 11.2 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 NPR3 PF03666.13 CDJ62226.1 - 0.46 9.2 15.0 0.53 9.0 15.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SOBP PF15279.6 CDJ62226.1 - 0.48 11.0 10.9 0.59 10.7 10.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Band_3_cyto PF07565.13 CDJ62226.1 - 0.67 9.7 7.1 0.86 9.3 7.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ferlin_C PF16165.5 CDJ62226.1 - 0.87 9.5 5.1 1.4 8.9 5.1 1.4 1 0 0 1 1 1 0 Ferlin C-terminus RR_TM4-6 PF06459.12 CDJ62226.1 - 0.89 9.3 14.1 1.2 9.0 14.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MCM_bind PF09739.9 CDJ62226.1 - 1.1 7.6 13.9 1.4 7.2 13.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4551 PF15087.6 CDJ62226.1 - 1.4 7.7 12.3 1.5 7.6 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Vfa1 PF08432.10 CDJ62226.1 - 1.6 9.0 18.5 2.6 8.4 18.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SLC12 PF03522.15 CDJ62226.1 - 1.8 7.5 10.0 2.1 7.3 10.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ62226.1 - 1.9 8.5 6.9 2.5 8.1 6.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PPL5 PF18168.1 CDJ62226.1 - 2.3 7.5 11.0 3.6 6.8 11.0 1.4 1 0 0 1 1 1 0 Prim-pol family 5 DUF2151 PF10221.9 CDJ62226.1 - 2.3 6.7 9.6 2.6 6.5 9.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Spem1 PF15670.5 CDJ62226.1 - 2.6 7.6 8.8 3.7 7.1 8.8 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Raftlin PF15250.6 CDJ62226.1 - 2.9 6.5 10.7 3.4 6.3 10.7 1.1 1 0 0 1 1 1 0 Raftlin Sec62 PF03839.16 CDJ62226.1 - 3.4 7.1 10.9 5 6.6 10.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Rib_recp_KP_reg PF05104.12 CDJ62226.1 - 5.5 8.0 49.2 0.24 12.4 42.6 1.8 1 1 1 2 2 2 0 Ribosome receptor lysine/proline rich region DUF2681 PF10883.8 CDJ62226.1 - 5.9 7.4 10.1 6.7 7.2 8.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) DUF755 PF05501.11 CDJ62226.1 - 6.8 7.0 51.6 23 5.3 51.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF755) ALMT PF11744.8 CDJ62226.1 - 8.1 5.1 12.8 9.7 4.9 12.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4614 PF15391.6 CDJ62227.1 - 2.5 8.1 11.8 5 7.1 11.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Ribosomal_60s PF00428.19 CDJ62227.1 - 7.3 7.3 15.9 0.12 12.9 8.3 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIS_M PF07500.14 CDJ62229.1 - 2.5e-22 79.5 0.0 8.1e-22 77.8 0.0 1.9 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CDJ62229.1 - 1.1e-18 66.7 4.9 1.1e-18 66.7 4.9 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CDJ62229.1 - 2.2e-11 43.6 0.1 4.2e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Elf1 PF05129.13 CDJ62229.1 - 0.026 14.6 0.6 0.066 13.3 0.6 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Band_3_cyto PF07565.13 CDJ62229.1 - 0.18 11.6 0.1 0.18 11.6 0.1 1.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Baculo_LEF5_C PF11792.8 CDJ62229.1 - 0.33 10.6 0.8 0.65 9.7 0.4 1.6 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Spt20 PF12090.8 CDJ62229.1 - 0.8 9.3 14.1 1.7 8.2 14.1 1.5 1 0 0 1 1 1 0 Spt20 family RIFIN PF02009.16 CDJ62229.1 - 1.2 9.0 7.7 4.7 7.0 2.5 2.4 2 0 0 2 2 2 0 Rifin Neur_chan_memb PF02932.16 CDJ62229.1 - 2.1 8.4 4.6 12 5.9 1.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SNRNP27 PF08648.12 CDJ62231.1 - 7.5e-26 90.0 0.4 1.5e-25 89.0 0.4 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins RskA PF10099.9 CDJ62231.1 - 0.0083 16.4 0.5 0.0083 16.4 0.5 2.1 2 0 0 2 2 2 1 Anti-sigma-K factor rskA JUPITER PF17054.5 CDJ62231.1 - 0.67 9.4 14.2 0.84 9.0 14.2 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter PNISR PF15996.5 CDJ62231.1 - 2.1 8.6 24.7 11 6.3 24.7 1.9 1 1 0 1 1 1 0 Arginine/serine-rich protein PNISR TAP35_44 PF07265.11 CDJ62232.1 - 0.35 10.9 2.4 0.52 10.3 2.3 1.7 1 1 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 Surface_antigen PF11054.8 CDJ62233.1 - 1.1e-76 257.7 3.6 1.3e-76 257.5 3.6 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62234.1 - 2.1e-66 224.1 1.4 2.4e-66 223.9 1.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62235.1 - 4e-69 233.0 3.5 4.7e-69 232.7 3.5 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF493 PF04359.14 CDJ62238.1 - 0.0001 22.8 0.0 39 4.9 0.0 4.4 4 0 0 4 4 4 3 Protein of unknown function (DUF493) YcgR PF07317.12 CDJ62238.1 - 0.0058 16.5 0.3 23 4.9 0.0 3.3 3 0 0 3 3 3 3 Flagellar regulator YcgR PRP3 PF08572.10 CDJ62238.1 - 0.18 11.5 21.9 2 8.1 0.7 4.2 2 1 1 4 4 4 0 pre-mRNA processing factor 3 (PRP3) DUF1635 PF07795.11 CDJ62240.1 - 0.0052 16.7 7.1 0.0071 16.2 7.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) SPX PF03105.19 CDJ62240.1 - 0.2 11.5 7.0 0.21 11.5 7.0 1.0 1 0 0 1 1 1 0 SPX domain BES1_N PF05687.13 CDJ62240.1 - 0.47 10.8 8.4 0.63 10.4 8.4 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal RAP1 PF07218.11 CDJ62240.1 - 0.64 8.2 8.5 0.66 8.2 8.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TFIIA PF03153.13 CDJ62240.1 - 0.69 9.9 6.5 0.75 9.7 6.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NAM-associated PF14303.6 CDJ62240.1 - 0.99 10.1 6.7 1.6 9.4 6.7 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF1180 PF06679.12 CDJ62240.1 - 1.2 9.5 8.0 1.6 9.1 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Miga PF10265.9 CDJ62240.1 - 1.3 7.9 6.4 1.5 7.7 6.4 1.0 1 0 0 1 1 1 0 Mitoguardin CCDC106 PF15794.5 CDJ62240.1 - 2.2 7.9 6.9 2.8 7.6 6.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 AF-4 PF05110.13 CDJ62240.1 - 5 5.1 18.9 6.1 4.8 18.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RT_RNaseH_2 PF17919.1 CDJ62243.1 - 3.2e-28 97.7 0.0 7.5e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ62243.1 - 3.4e-18 65.8 0.0 1e-17 64.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ62243.1 - 1.8e-14 53.9 0.0 8.9e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ62243.1 - 3.3e-13 49.5 2.5 7.7e-13 48.4 2.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 CDJ62243.1 - 6e-12 45.5 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ62243.1 - 2.3e-08 34.6 0.0 5.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ62243.1 - 4.3e-08 33.6 0.0 1.1e-07 32.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 CDJ62243.1 - 3e-07 30.3 0.0 5.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 CDJ62243.1 - 0.00013 21.5 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 CDJ62243.1 - 0.00026 21.1 0.5 0.00066 19.8 0.5 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVP PF00077.20 CDJ62243.1 - 0.027 14.8 0.0 0.24 11.7 0.0 2.7 1 1 0 1 1 1 0 Retroviral aspartyl protease Spt20 PF12090.8 CDJ62245.1 - 0.27 10.8 19.8 0.091 12.4 4.1 2.3 2 0 0 2 2 2 0 Spt20 family DUF1980 PF09323.10 CDJ62245.1 - 6.4 6.6 5.8 15 5.4 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) TFIIA PF03153.13 CDJ62246.1 - 0.013 15.6 38.5 0.016 15.3 38.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Choline_kinase PF01633.20 CDJ62246.1 - 0.65 9.5 5.8 0.95 9.0 5.8 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase CCSAP PF15748.5 CDJ62246.1 - 0.83 9.8 20.6 1.1 9.4 20.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated GIDA_assoc PF13932.6 CDJ62246.1 - 1.9 8.6 9.7 2.4 8.3 9.7 1.2 1 0 0 1 1 1 0 GidA associated domain RR_TM4-6 PF06459.12 CDJ62246.1 - 2 8.2 13.7 2.6 7.8 13.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S64 PF08192.11 CDJ62246.1 - 3.8 5.9 17.1 4.3 5.7 17.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.9 CDJ62246.1 - 4.6 5.4 28.3 5 5.3 28.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ62246.1 - 6.8 3.7 21.0 6.8 3.7 21.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 CDJ62246.1 - 7.1 5.3 18.8 9.4 4.9 18.8 1.2 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ62246.1 - 8.2 5.3 17.6 10 4.9 17.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TRAPP PF04051.16 CDJ62248.1 - 2.5e-16 59.7 0.0 2.6e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3793 PF12672.7 CDJ62248.1 - 0.055 13.5 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) DUF755 PF05501.11 CDJ62249.1 - 0.00086 19.6 9.5 0.00086 19.6 9.5 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF755) Utp14 PF04615.13 CDJ62249.1 - 0.061 11.9 16.7 0.07 11.7 16.7 1.0 1 0 0 1 1 1 0 Utp14 protein EIIBC-GUT_N PF03612.14 CDJ62249.1 - 0.67 9.7 12.4 14 5.3 2.6 3.3 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus CAF20 PF17052.5 CDJ62249.1 - 0.82 9.8 12.4 0.41 10.8 6.4 2.6 2 1 0 2 2 2 0 Cap associated factor SR-25 PF10500.9 CDJ62249.1 - 1.9 8.0 26.9 0.21 11.2 15.7 2.4 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein WBP-1 PF11669.8 CDJ62249.1 - 4 8.1 20.2 1.4 9.6 3.2 3.4 3 0 0 3 3 3 0 WW domain-binding protein 1 GTP_EFTU PF00009.27 CDJ62250.1 - 3.1e-32 111.7 1.7 2.1e-31 109.0 1.8 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDJ62250.1 - 2e-16 60.0 0.0 2.6e-11 43.6 0.0 3.5 3 0 0 3 3 3 2 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CDJ62250.1 - 7.6e-08 32.4 0.3 1.7e-07 31.3 0.3 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CDJ62250.1 - 8.6e-06 26.0 0.9 2.8e-05 24.3 0.9 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ62250.1 - 5.7e-05 22.8 0.3 0.00012 21.8 0.3 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDJ62250.1 - 0.00046 19.7 0.0 0.00096 18.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CDJ62250.1 - 0.0025 17.9 4.6 0.011 15.8 0.2 3.3 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 CDJ62250.1 - 0.0032 17.4 9.0 0.045 13.7 0.9 3.1 2 1 1 3 3 2 2 RsgA GTPase PduV-EutP PF10662.9 CDJ62250.1 - 0.0045 16.7 2.6 0.028 14.2 2.6 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 CDJ62250.1 - 0.018 14.6 0.2 0.035 13.6 0.2 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 CDJ62250.1 - 0.027 13.7 0.2 0.074 12.3 0.2 1.6 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 CDJ62250.1 - 0.12 12.9 0.1 0.12 12.9 0.1 4.0 4 1 0 4 4 3 0 ABC transporter Sin_N PF04801.13 CDJ62250.1 - 0.73 9.0 0.0 0.73 9.0 0.0 5.5 4 2 2 6 6 3 0 Sin-like protein conserved region Ribosomal_L21p PF00829.21 CDJ62252.1 - 8.3e-20 70.9 0.0 1.1e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein YajC PF02699.15 CDJ62252.1 - 0.034 14.0 0.9 0.062 13.2 0.9 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit TFIIA PF03153.13 CDJ62253.1 - 5.8 6.8 16.7 8.4 6.3 16.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_4 PF13637.6 CDJ62254.1 - 1.7e-06 28.4 0.2 2.1 9.0 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ62254.1 - 2.7e-06 27.3 0.8 9.8 7.1 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 CDJ62254.1 - 1.4e-05 25.6 6.6 0.025 15.1 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ62254.1 - 0.014 15.7 2.2 20 5.6 0.1 4.0 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ribosomal_L38e PF01781.18 CDJ62255.1 - 2e-28 98.3 0.5 2.3e-28 98.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Succ_CoA_lig PF13607.6 CDJ62255.1 - 0.14 12.0 0.6 0.19 11.5 0.6 1.1 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain SRR1 PF07985.12 CDJ62256.1 - 2.7e-13 49.7 0.5 5.3e-13 48.8 0.5 1.5 1 0 0 1 1 1 1 SRR1 Med3 PF11593.8 CDJ62256.1 - 0.012 14.8 1.5 0.012 14.8 1.5 3.5 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal Rotamase_2 PF13145.6 CDJ62256.1 - 0.044 14.6 1.5 0.044 14.6 1.5 3.3 4 0 0 4 4 4 0 PPIC-type PPIASE domain TFIIA PF03153.13 CDJ62256.1 - 0.057 13.4 10.4 0.5 10.3 2.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ62256.1 - 0.74 9.9 21.7 4.4 7.4 6.2 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Collagen PF01391.18 CDJ62257.1 - 6.4e-07 29.0 30.4 6.4e-07 29.0 30.4 2.7 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) SLX9 PF15341.6 CDJ62258.1 - 0.0023 18.3 2.5 0.16 12.4 0.0 2.5 2 0 0 2 2 2 2 Ribosome biogenesis protein SLX9 Herpes_UL37_1 PF03970.13 CDJ62258.1 - 0.19 10.9 2.4 0.32 10.2 2.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein zf-ZPR1 PF03367.13 CDJ62259.1 - 1.5e-64 216.7 5.0 1.7e-50 171.0 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Zn_Tnp_IS1595 PF12760.7 CDJ62259.1 - 0.0013 18.6 17.2 0.022 14.7 0.5 4.5 3 1 1 4 4 4 2 Transposase zinc-ribbon domain HypA PF01155.19 CDJ62259.1 - 0.0075 16.3 9.1 0.28 11.2 4.0 2.6 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Eapp_C PF10238.9 CDJ62259.1 - 0.29 11.2 4.6 11 6.0 0.0 3.0 3 0 0 3 3 3 0 E2F-associated phosphoprotein Zn-ribbon_8 PF09723.10 CDJ62259.1 - 2.3 8.4 14.1 7.3 6.8 1.0 4.3 4 0 0 4 4 4 0 Zinc ribbon domain DSBA PF01323.20 CDJ62259.1 - 6.1 6.6 6.3 2.1 8.1 1.2 2.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Spt20 PF12090.8 CDJ62260.1 - 0.0018 17.9 4.7 0.0018 17.9 4.7 1.1 1 0 0 1 1 1 1 Spt20 family SARAF PF06682.12 CDJ62260.1 - 0.0041 16.8 4.2 0.005 16.5 4.2 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis TFIIA PF03153.13 CDJ62260.1 - 0.029 14.4 5.1 0.028 14.4 5.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 CDJ62260.1 - 0.53 9.1 8.0 0.6 8.9 8.0 1.1 1 0 0 1 1 1 0 Androgen receptor MIP-T3_C PF17749.1 CDJ62261.1 - 0.0057 16.6 0.2 0.008 16.2 0.2 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region Lant_dehydr_N PF04738.13 CDJ62261.1 - 0.017 13.3 0.1 0.02 13.0 0.1 1.1 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus Exo84_C PF16528.5 CDJ62261.1 - 0.018 14.8 0.6 5.8 6.7 0.0 2.1 1 1 1 2 2 2 0 Exocyst component 84 C-terminal DUF883 PF05957.13 CDJ62261.1 - 0.039 14.6 3.3 0.089 13.4 0.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Exonuc_VII_L PF02601.15 CDJ62261.1 - 0.041 13.4 0.2 0.052 13.1 0.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlgN PF05130.12 CDJ62261.1 - 0.091 13.3 1.9 0.22 12.0 1.4 1.8 1 1 1 2 2 2 0 FlgN protein DUF16 PF01519.16 CDJ62261.1 - 0.091 13.3 0.1 6.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF2203 PF09969.9 CDJ62261.1 - 0.12 13.1 1.3 0.63 10.8 0.4 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Apolipoprotein PF01442.18 CDJ62261.1 - 0.28 11.0 6.3 0.09 12.6 1.3 2.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Peptidase_M75 PF09375.10 CDJ62261.1 - 0.47 9.9 8.2 0.91 8.9 8.0 1.5 1 1 0 1 1 1 0 Imelysin FKBP_N PF01346.18 CDJ62261.1 - 5.1 8.1 6.5 1.1 10.3 2.2 1.9 1 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Pkinase PF00069.25 CDJ62262.1 - 0.0017 17.8 0.0 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Sporozoite_P67 PF05642.11 CDJ62262.1 - 0.11 10.6 3.1 0.23 9.5 3.1 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.9 CDJ62262.1 - 5.3 5.5 17.2 0.047 12.3 8.5 2.0 2 0 0 2 2 2 0 Macoilin family Exo5 PF09810.9 CDJ62263.1 - 3e-35 122.4 0.1 3e-35 122.4 0.1 5.3 4 1 1 5 5 5 2 Exonuclease V - a 5' deoxyribonuclease DUF2722 PF10846.8 CDJ62263.1 - 0.0036 16.3 14.7 0.0036 16.3 14.7 6.0 3 1 1 5 5 5 2 Protein of unknown function (DUF2722) PhetRS_B1 PF18262.1 CDJ62264.1 - 5.6e-28 97.0 0.0 7.5e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain RRM_1 PF00076.22 CDJ62266.1 - 4.6e-15 55.2 0.0 5.1e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ62266.1 - 0.19 11.4 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.24 CDJ62267.1 - 8e-86 288.6 0.0 1.1e-85 288.1 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Spt20 PF12090.8 CDJ62267.1 - 6.7e-05 22.6 22.9 0.0054 16.4 13.9 2.3 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ62267.1 - 0.005 15.8 23.5 0.14 11.0 16.8 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Lin-8 PF03353.15 CDJ62267.1 - 0.25 10.9 12.7 0.37 10.3 9.1 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ62267.1 - 0.42 9.4 15.2 0.72 8.6 15.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ62267.1 - 0.44 10.1 37.9 2.3 7.8 13.5 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ62267.1 - 0.66 9.9 15.8 2.4 8.1 8.8 3.1 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.8 CDJ62267.1 - 3 6.7 28.1 0.021 13.8 7.7 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Coilin_N PF15862.5 CDJ62267.1 - 7.1 6.4 17.6 0.77 9.6 9.3 3.0 3 0 0 3 3 3 0 Coilin N-terminus Pkinase PF00069.25 CDJ62269.1 - 0.019 14.3 0.0 0.019 14.3 0.0 2.6 2 0 0 2 2 2 0 Protein kinase domain SPX PF03105.19 CDJ62269.1 - 0.021 14.7 0.1 0.021 14.7 0.1 9.5 4 3 4 8 8 8 0 SPX domain US30 PF17624.2 CDJ62269.1 - 0.44 9.5 4.7 3.2 6.7 4.7 2.6 1 0 0 1 1 1 0 Family of unknown function RR_TM4-6 PF06459.12 CDJ62270.1 - 0.38 10.5 14.6 0.63 9.8 14.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ62270.1 - 0.4 9.6 19.1 0.49 9.3 19.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 CDJ62270.1 - 0.98 9.6 11.4 29 4.8 11.3 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Neur_chan_memb PF02932.16 CDJ62270.1 - 1.3 9.0 9.7 1.7 8.6 9.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ62270.1 - 1.9 7.4 11.5 2.8 6.9 11.5 1.2 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 CDJ62270.1 - 3.7 6.2 20.7 5.8 5.6 20.7 1.3 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 CDJ62270.1 - 4 6.8 16.5 5.7 6.3 16.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF913 PF06025.12 CDJ62270.1 - 4.2 6.3 10.3 7 5.5 10.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.6 CDJ62270.1 - 5.6 5.3 4.6 6.7 5.0 4.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Rrn6 PF10214.9 CDJ62270.1 - 6.7 5.1 23.9 7.8 4.8 23.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor WBS_methylT PF12589.8 CDJ62271.1 - 3.7e-13 50.0 7.0 3.7e-13 50.0 7.0 2.4 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome RskA PF10099.9 CDJ62271.1 - 0.003 17.9 1.4 0.0042 17.4 1.4 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA PRR18 PF15671.5 CDJ62271.1 - 0.0053 16.7 1.2 0.0089 15.9 1.2 1.3 1 0 0 1 1 1 1 Proline-rich protein family 18 Ribosomal_60s PF00428.19 CDJ62271.1 - 0.014 16.0 10.2 0.038 14.6 10.2 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein K_channel_TID PF07941.11 CDJ62271.1 - 0.031 14.7 12.1 0.031 14.7 12.1 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF3682 PF12446.8 CDJ62271.1 - 0.094 13.2 7.6 0.23 11.9 7.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Presenilin PF01080.17 CDJ62272.1 - 0.087 11.6 7.9 0.12 11.1 7.9 1.2 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 CDJ62272.1 - 0.19 11.6 11.6 0.26 11.1 11.6 1.1 1 0 0 1 1 1 0 SPX domain FHIPEP PF00771.20 CDJ62272.1 - 0.34 9.3 3.2 0.44 9.0 3.2 1.1 1 0 0 1 1 1 0 FHIPEP family GREB1 PF15782.5 CDJ62272.1 - 0.5 7.4 14.3 0.56 7.3 14.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2722 PF10846.8 CDJ62272.1 - 0.75 8.7 24.8 0.3 10.0 13.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) BRF1 PF07741.13 CDJ62272.1 - 0.76 10.2 6.0 0.83 10.0 3.9 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain SelK_SelG PF10961.8 CDJ62272.1 - 1.6 9.4 4.2 13 6.5 0.0 2.9 3 0 0 3 3 3 0 Selenoprotein SelK_SelG Connexin PF00029.19 CDJ62272.1 - 2.3 7.9 4.4 1.2 8.8 2.3 1.4 1 1 1 2 2 2 0 Connexin DUF1840 PF08895.11 CDJ62272.1 - 3.2 8.1 9.8 5.3 7.4 6.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Borrelia_P83 PF05262.11 CDJ62272.1 - 3.5 6.0 8.3 5.7 5.3 8.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4834 PF16118.5 CDJ62272.1 - 3.7 8.6 11.5 5.7 8.0 5.8 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) Roughex PF06020.11 CDJ62272.1 - 3.9 6.5 10.5 1.6 7.7 3.4 2.2 2 0 0 2 2 2 0 Drosophila roughex protein Ctr PF04145.15 CDJ62272.1 - 6.4 7.4 12.0 0.35 11.5 0.3 2.3 1 1 1 2 2 2 0 Ctr copper transporter family eIF_4EBP PF05456.11 CDJ62272.1 - 7 6.6 9.2 0.58 10.1 4.2 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) ParA PF10609.9 CDJ62273.1 - 4.6e-07 29.5 11.8 4.3e-06 26.3 5.1 2.6 2 1 1 3 3 3 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CDJ62273.1 - 0.00023 21.2 0.3 0.0005 20.1 0.3 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 CDJ62273.1 - 0.00048 20.1 0.5 0.0025 17.7 0.2 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 CDJ62273.1 - 0.00077 19.1 0.2 0.0021 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 CDJ62273.1 - 0.00093 18.5 1.5 0.00093 18.5 1.5 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 CDJ62273.1 - 0.0022 17.9 1.5 0.0047 16.9 1.5 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CDJ62273.1 - 0.0033 16.7 0.5 0.0033 16.7 0.5 1.7 2 0 0 2 2 2 1 NB-ARC domain TsaE PF02367.17 CDJ62273.1 - 0.016 15.2 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 CDJ62273.1 - 0.036 14.0 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Presenilin PF01080.17 CDJ62273.1 - 0.045 12.5 2.7 0.056 12.2 2.7 1.1 1 0 0 1 1 1 0 Presenilin DUF3824 PF12868.7 CDJ62273.1 - 0.048 14.3 0.5 0.048 14.3 0.5 3.4 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) EphA2_TM PF14575.6 CDJ62273.1 - 0.05 14.5 2.3 0.11 13.3 0.2 2.3 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain AAA_18 PF13238.6 CDJ62273.1 - 0.056 14.0 0.5 0.056 14.0 0.5 1.8 2 0 0 2 2 2 0 AAA domain DUF2681 PF10883.8 CDJ62273.1 - 0.15 12.5 18.8 1.6 9.2 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Gram_pos_anchor PF00746.21 CDJ62273.1 - 0.34 10.9 0.2 0.34 10.9 0.2 3.2 3 0 0 3 3 2 0 LPXTG cell wall anchor motif Ndc1_Nup PF09531.10 CDJ62273.1 - 0.38 9.4 3.1 0.46 9.1 3.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LapA_dom PF06305.11 CDJ62273.1 - 0.44 10.4 4.6 0.12 12.2 0.8 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Herpes_DNAp_acc PF04929.12 CDJ62273.1 - 0.87 8.5 7.1 1.3 7.9 7.1 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor HemX PF04375.14 CDJ62273.1 - 0.91 8.7 16.8 1.5 8.1 16.8 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase WBP-1 PF11669.8 CDJ62273.1 - 1.1 9.9 6.4 0.4 11.3 2.3 2.0 2 0 0 2 2 2 0 WW domain-binding protein 1 RskA PF10099.9 CDJ62273.1 - 2.1 8.6 43.7 0.082 13.2 11.3 3.1 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF5349 PF17298.2 CDJ62273.1 - 2.2 7.9 7.3 0.85 9.3 3.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5349) AAA_24 PF13479.6 CDJ62273.1 - 2.7 7.7 5.1 1.5 8.5 1.5 2.0 2 0 0 2 2 2 0 AAA domain DUF4834 PF16118.5 CDJ62273.1 - 4.3 8.4 8.0 3.8 8.5 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) COG4 PF08318.12 CDJ62274.1 - 8.3e-11 41.5 1.0 8.3e-11 41.5 1.0 4.6 3 2 1 4 4 4 1 COG4 transport protein RAP1 PF07218.11 CDJ62274.1 - 3 6.0 14.3 6 5.0 14.3 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TSP_1 PF00090.19 CDJ62275.1 - 9.6e-19 67.3 40.1 9.5e-09 35.3 1.2 6.7 5 1 0 5 5 5 3 Thrombospondin type 1 domain Syndecan PF01034.20 CDJ62275.1 - 0.15 12.0 0.5 0.29 11.1 0.5 1.5 1 0 0 1 1 1 0 Syndecan domain Pkinase PF00069.25 CDJ62276.1 - 1.1e-37 129.8 0.1 2e-34 119.2 0.0 3.4 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ62276.1 - 1.7e-10 40.6 1.5 3.6e-08 33.0 0.0 3.3 2 1 0 3 3 3 1 Protein tyrosine kinase PAN_1 PF00024.26 CDJ62276.1 - 8.1e-06 25.7 2.6 0.048 13.6 0.0 3.0 3 0 0 3 3 3 2 PAN domain PAN_3 PF08277.12 CDJ62276.1 - 0.0011 18.8 0.3 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 PAN-like domain Herpes_pp85 PF04637.12 CDJ62276.1 - 0.052 12.0 2.0 0.083 11.3 2.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PAN_4 PF14295.6 CDJ62276.1 - 0.21 11.5 4.8 1.9 8.5 0.1 2.8 3 0 0 3 3 3 0 PAN domain JUPITER PF17054.5 CDJ62276.1 - 0.84 9.0 5.4 1.6 8.1 5.4 1.4 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Suf PF05843.14 CDJ62277.1 - 0.0035 17.4 10.1 0.0035 17.4 10.1 1.6 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) DUF1980 PF09323.10 CDJ62277.1 - 0.01 15.8 4.8 0.019 14.9 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) eIF-3_zeta PF05091.12 CDJ62277.1 - 0.038 13.0 9.8 0.047 12.7 9.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ62277.1 - 0.048 14.6 7.0 0.048 14.6 7.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ62277.1 - 0.27 11.0 2.4 0.41 10.4 2.4 1.4 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 CDJ62277.1 - 0.6 9.0 4.6 0.84 8.5 4.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) CSG2 PF16965.5 CDJ62277.1 - 1.2 8.0 2.7 1.7 7.5 2.7 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Peptidase_S49_N PF08496.10 CDJ62277.1 - 1.2 9.2 11.7 1 9.4 4.7 2.5 2 1 0 2 2 2 0 Peptidase family S49 N-terminal EOS1 PF12326.8 CDJ62277.1 - 2.7 7.9 5.3 3.1 7.7 5.3 1.3 1 1 0 1 1 1 0 N-glycosylation protein CLN3 PF02487.17 CDJ62277.1 - 3.6 6.5 5.8 6.3 5.7 5.8 1.4 1 0 0 1 1 1 0 CLN3 protein DEAD PF00270.29 CDJ62278.1 - 1.4e-33 116.1 0.4 1.4e-33 116.1 0.4 3.7 3 2 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ62278.1 - 4e-25 88.3 0.2 4e-25 88.3 0.2 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Vps39_1 PF10366.9 CDJ62278.1 - 0.0015 18.8 0.3 0.0015 18.8 0.3 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 RskA PF10099.9 CDJ62278.1 - 0.011 16.1 14.6 0.011 16.1 14.6 6.0 1 1 2 4 4 4 0 Anti-sigma-K factor rskA tRNA-synt_1b PF00579.25 CDJ62279.1 - 7.9e-35 120.6 0.1 1.6e-26 93.3 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) IMUP PF15761.5 CDJ62279.1 - 0.0036 18.0 12.5 0.33 11.7 4.3 2.6 2 0 0 2 2 2 2 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ62279.1 - 0.027 14.1 15.0 0.8 9.3 8.6 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ62279.1 - 0.042 14.2 14.0 0.49 10.7 5.6 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Chorion_2 PF03964.15 CDJ62279.1 - 8.7 7.2 30.1 0.34 11.8 2.1 4.3 3 1 1 4 4 4 0 Chorion family 2 DUF2967 PF11179.8 CDJ62281.1 - 0.0026 16.0 2.7 0.0026 16.0 2.7 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF2967) SUIM_assoc PF16619.5 CDJ62281.1 - 0.019 15.0 1.6 0.019 15.0 1.6 3.6 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ62281.1 - 0.11 12.0 16.9 0.49 10.0 5.9 2.5 2 0 0 2 2 2 0 Spt20 family Apt1 PF10351.9 CDJ62281.1 - 0.49 9.2 13.0 1.1 8.1 4.6 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain RRS1 PF04939.12 CDJ62282.1 - 5.2e-35 120.7 7.2 3.5e-34 118.0 7.2 2.0 1 1 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) QRPTase_C PF01729.19 CDJ62282.1 - 0.37 10.5 3.9 0.17 11.7 1.7 1.5 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain RskA PF10099.9 CDJ62283.1 - 1.7e-07 31.7 26.3 0.00036 20.9 19.9 3.3 1 1 1 2 2 2 2 Anti-sigma-K factor rskA Roughex PF06020.11 CDJ62283.1 - 0.0067 15.6 8.6 0.0067 15.6 8.6 2.3 2 0 0 2 2 2 1 Drosophila roughex protein NTP_transf_3 PF12804.7 CDJ62283.1 - 0.0083 16.5 8.9 0.016 15.6 8.9 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain SDA1 PF05285.12 CDJ62283.1 - 0.0089 15.5 14.4 0.017 14.6 14.4 1.3 1 0 0 1 1 1 1 SDA1 DUF4770 PF15994.5 CDJ62283.1 - 0.044 14.0 13.9 0.45 10.7 4.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) PAT1 PF09770.9 CDJ62283.1 - 0.07 11.4 20.9 0.091 11.0 20.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0565 PF10561.9 CDJ62283.1 - 0.23 10.6 0.0 0.23 10.6 0.0 2.8 1 1 1 2 2 1 0 Uncharacterised protein family UPF0565 DUF2235 PF09994.9 CDJ62283.1 - 0.26 10.6 3.4 0.26 10.6 0.7 2.0 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Plasmodium_Vir PF05795.11 CDJ62283.1 - 0.51 9.7 11.8 0.085 12.3 3.1 2.8 3 0 0 3 3 3 0 Plasmodium vivax Vir protein FlaG PF03646.15 CDJ62283.1 - 0.73 10.0 28.0 0.35 11.1 12.8 2.8 3 0 0 3 3 3 0 FlaG protein Fmp27_WPPW PF10359.9 CDJ62283.1 - 1 8.1 21.7 0.1 11.5 14.4 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Enkurin PF13864.6 CDJ62283.1 - 1.2 9.7 20.5 0.44 11.0 11.8 2.5 2 0 0 2 2 2 0 Calmodulin-binding ARD PF03079.14 CDJ62283.1 - 1.3 9.2 7.1 0.42 10.8 3.2 1.8 2 0 0 2 2 2 0 ARD/ARD' family PEX11 PF05648.14 CDJ62283.1 - 1.8 8.0 8.3 3.9 6.9 2.3 2.4 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) MAT1 PF06391.13 CDJ62283.1 - 1.8 8.3 24.9 0.93 9.3 12.4 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 MPM1 PF17234.2 CDJ62283.1 - 2.5 8.3 18.7 4.9 7.4 9.9 2.4 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF3391 PF11871.8 CDJ62283.1 - 3.2 8.3 28.3 7.5 7.1 1.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Anoctamin PF04547.12 CDJ62283.1 - 3.4 6.4 5.4 0.85 8.4 1.2 1.8 2 0 0 2 2 2 0 Calcium-activated chloride channel DUF3464 PF11947.8 CDJ62283.1 - 3.7 7.3 12.4 11 5.7 5.2 2.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Bud13 PF09736.9 CDJ62283.1 - 3.9 7.9 19.4 9.1 6.7 1.9 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Eapp_C PF10238.9 CDJ62283.1 - 4.6 7.3 13.8 12 5.9 0.8 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4667 PF15700.5 CDJ62283.1 - 5.4 7.0 26.0 0.19 11.8 7.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) DUF1645 PF07816.11 CDJ62283.1 - 6 7.4 33.3 1 9.9 10.0 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF1645) SpoIIP PF07454.11 CDJ62283.1 - 7.9 5.8 13.8 11 5.3 6.6 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DDRGK PF09756.9 CDJ62283.1 - 8.3 5.9 26.4 0.73 9.4 11.8 2.2 2 0 0 2 2 2 0 DDRGK domain ALMT PF11744.8 CDJ62283.1 - 8.8 5.0 15.5 0.39 9.5 7.4 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter MORN PF02493.20 CDJ62284.1 - 8.6e-05 22.2 1.5 8.6e-05 22.2 1.5 2.7 3 0 0 3 3 3 1 MORN repeat NST1 PF13945.6 CDJ62284.1 - 0.046 13.8 6.8 0.061 13.4 6.8 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Lin-8 PF03353.15 CDJ62284.1 - 0.21 11.1 5.8 0.26 10.8 5.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hamartin PF04388.12 CDJ62284.1 - 1.2 7.7 6.9 1.4 7.5 6.9 1.1 1 0 0 1 1 1 0 Hamartin protein Spt20 PF12090.8 CDJ62284.1 - 4.2 6.9 11.3 5.6 6.5 11.3 1.1 1 0 0 1 1 1 0 Spt20 family CPSF100_C PF13299.6 CDJ62284.1 - 7.9 6.6 11.4 10 6.3 10.6 1.5 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3807 PF12720.7 CDJ62284.1 - 8.4 6.6 14.0 12 6.2 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) GET2 PF08690.10 CDJ62285.1 - 0.00056 19.7 2.6 0.00056 19.7 2.6 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 BatD PF13584.6 CDJ62285.1 - 0.00095 18.1 1.2 0.00096 18.1 1.2 1.0 1 0 0 1 1 1 1 Oxygen tolerance Orf78 PF06024.12 CDJ62285.1 - 0.0011 19.3 0.6 0.0012 19.1 0.6 1.0 1 0 0 1 1 1 1 Orf78 (ac78) DUF2207 PF09972.9 CDJ62285.1 - 0.0024 16.7 0.1 0.0024 16.7 0.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 CDJ62285.1 - 0.0029 17.8 0.4 0.0032 17.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DcuC PF03606.15 CDJ62285.1 - 0.0039 15.7 0.2 0.0041 15.6 0.2 1.0 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier Pex14_N PF04695.13 CDJ62285.1 - 0.0044 17.7 4.4 0.0044 17.7 4.4 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region T2SSF PF00482.23 CDJ62285.1 - 0.0092 15.9 0.1 0.0095 15.9 0.1 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F Consortin_C PF15281.6 CDJ62285.1 - 0.012 15.6 0.5 0.014 15.4 0.5 1.1 1 0 0 1 1 1 0 Consortin C-terminus DUF2417 PF10329.9 CDJ62285.1 - 0.017 14.6 0.1 0.017 14.6 0.1 1.0 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Vac7 PF12751.7 CDJ62285.1 - 0.021 14.3 0.6 0.021 14.3 0.6 1.0 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Peroxin-13_N PF04088.13 CDJ62285.1 - 0.028 14.7 0.5 0.028 14.7 0.5 1.0 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4366 PF14283.6 CDJ62285.1 - 0.035 14.2 0.0 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4436 PF14494.6 CDJ62285.1 - 0.058 12.7 0.0 0.061 12.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) TMEM154 PF15102.6 CDJ62285.1 - 0.067 13.1 0.2 0.071 13.0 0.2 1.1 1 0 0 1 1 1 0 TMEM154 protein family GWT1 PF06423.12 CDJ62285.1 - 0.12 12.6 0.3 0.12 12.5 0.3 1.0 1 0 0 1 1 1 0 GWT1 DUF2722 PF10846.8 CDJ62285.1 - 0.15 11.0 19.0 0.15 11.0 19.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CrgA PF06781.12 CDJ62285.1 - 0.16 12.1 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Cell division protein CrgA DUF5336 PF17270.2 CDJ62285.1 - 0.23 11.1 7.6 0.26 10.9 7.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5336) DUF4175 PF13779.6 CDJ62285.1 - 0.65 7.8 13.4 0.59 8.0 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TraG_N PF07916.11 CDJ62285.1 - 0.77 8.5 4.9 0.77 8.5 4.9 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Suf PF05843.14 CDJ62285.1 - 0.99 9.3 8.5 0.97 9.4 8.5 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EIIBC-GUT_N PF03612.14 CDJ62285.1 - 3.1 7.5 5.6 3.2 7.5 5.6 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF5349 PF17298.2 CDJ62285.1 - 3.6 7.3 11.5 3.7 7.2 11.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Lyase_1 PF00206.20 CDJ62286.1 - 1.3e-06 28.1 0.0 1.5e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Lyase Med26 PF08711.11 CDJ62288.1 - 6.9e-07 29.2 0.0 6.9e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 TFIIS helical bundle-like domain SR-25 PF10500.9 CDJ62288.1 - 0.0039 16.9 9.2 0.0039 16.9 9.2 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein RNA_polI_A34 PF08208.11 CDJ62288.1 - 1.4 9.0 21.1 6.4 6.8 0.4 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Zip PF02535.22 CDJ62288.1 - 1.6 7.9 6.9 0.037 13.2 0.8 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter TFIIA PF03153.13 CDJ62288.1 - 2.7 7.9 31.4 0.3 11.0 19.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UreE_C PF05194.12 CDJ62288.1 - 2.8 8.5 13.3 2.9 8.4 8.9 2.3 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain DDHD PF02862.17 CDJ62288.1 - 3.1 7.9 10.8 3.2 7.8 3.4 2.3 2 0 0 2 2 2 0 DDHD domain GAGA_bind PF06217.12 CDJ62288.1 - 3.5 7.8 18.0 1.7 8.8 9.4 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family DUF3807 PF12720.7 CDJ62288.1 - 7 6.9 28.1 4.8 7.4 16.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Pkinase_fungal PF17667.1 CDJ62288.1 - 9.6 4.8 9.5 2.9 6.6 3.3 2.0 2 0 0 2 2 2 0 Fungal protein kinase DUF1298 PF06974.13 CDJ62289.1 - 1.7e-21 76.7 0.0 3.1e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 CDJ62289.1 - 8.5e-07 29.0 9.7 0.0006 19.7 1.1 3.1 3 0 0 3 3 3 2 Wax ester synthase-like Acyl-CoA acyltransferase domain LapA_dom PF06305.11 CDJ62289.1 - 0.62 9.9 8.2 0.15 11.9 2.8 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain HSP70 PF00012.20 CDJ62290.1 - 3.5e-258 857.7 11.2 4e-258 857.5 11.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ62290.1 - 1.9e-20 72.9 2.0 1.8e-19 69.7 0.8 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CDJ62290.1 - 0.00018 21.9 2.8 0.31 11.5 0.1 3.5 3 2 0 3 3 3 2 Cell division protein FtsA Radial_spoke_3 PF06098.11 CDJ62290.1 - 0.0011 18.3 0.8 0.0011 18.3 0.8 1.6 2 0 0 2 2 2 1 Radial spoke protein 3 DDR PF08841.10 CDJ62290.1 - 0.013 14.6 0.2 1.8 7.5 0.1 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 CDJ62290.1 - 0.013 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain SIKE PF05769.11 CDJ62290.1 - 0.081 12.9 0.2 0.081 12.9 0.2 2.0 2 0 0 2 2 2 0 SIKE family CENP-Q PF13094.6 CDJ62290.1 - 0.52 10.5 4.3 8.9 6.5 0.8 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit MACPF PF01823.19 CDJ62291.1 - 2.3e-36 125.9 0.4 5e-36 124.8 0.0 1.7 2 0 0 2 2 2 1 MAC/Perforin domain partial_CstF PF15861.5 CDJ62293.1 - 0.0019 18.0 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Partial cleavage stimulation factor domain CTP_transf_like PF01467.26 CDJ62294.1 - 7.8e-32 110.4 0.0 1.3e-15 57.8 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CDJ62294.1 - 0.005 16.7 0.6 0.63 9.9 0.0 2.5 2 0 0 2 2 2 2 FAD synthetase WSD PF15613.6 CDJ62294.1 - 0.062 13.8 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif CTU2 PF10288.9 CDJ62294.1 - 0.086 13.1 0.7 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Spt20 PF12090.8 CDJ62294.1 - 0.32 10.6 7.5 0.5 9.9 7.5 1.2 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 CDJ62295.1 - 0.027 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Spt20 PF12090.8 CDJ62295.1 - 5.9 6.4 7.9 10 5.6 7.9 1.3 1 0 0 1 1 1 0 Spt20 family RT_RNaseH_2 PF17919.1 CDJ62296.1 - 2.4e-29 101.3 0.0 5.8e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ62296.1 - 3.2e-28 98.1 0.1 7.6e-28 96.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ62296.1 - 1.1e-09 38.5 0.0 1.3e-08 35.0 0.0 2.5 2 1 0 2 2 2 1 Integrase core domain Chromo PF00385.24 CDJ62296.1 - 3.1e-07 30.2 0.0 6.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 CDJ62296.1 - 0.00021 20.9 0.0 0.00041 19.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 CDJ62298.1 - 6e-14 51.7 0.0 8.9e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PIG-U PF06728.13 CDJ62299.1 - 5e-43 147.6 7.8 9.5e-43 146.7 7.8 1.4 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U BAF1_ABF1 PF04684.13 CDJ62299.1 - 0.0027 16.9 0.9 0.0027 16.9 0.9 2.8 3 0 0 3 3 2 1 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ62299.1 - 0.0051 16.9 38.5 0.19 11.7 22.2 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 CDJ62299.1 - 0.0087 16.0 13.8 0.19 11.6 6.0 2.2 1 1 1 2 2 2 2 Velvet factor V_ATPase_I PF01496.19 CDJ62299.1 - 0.025 12.5 10.1 0.18 9.7 0.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 CDJ62299.1 - 0.11 12.0 17.1 0.19 11.3 17.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit EPL1 PF10513.9 CDJ62299.1 - 0.16 12.4 10.2 5.3 7.4 0.1 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like AIF_C PF14721.6 CDJ62299.1 - 0.16 12.3 8.1 0.99 9.8 0.1 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SpoIIP PF07454.11 CDJ62299.1 - 0.2 11.1 8.0 2.5 7.5 4.9 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Hid1 PF12722.7 CDJ62299.1 - 0.25 9.4 8.0 0.44 8.6 8.0 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Connexin PF00029.19 CDJ62299.1 - 0.31 10.8 10.5 0.95 9.2 4.7 2.3 1 1 1 2 2 2 0 Connexin Suf PF05843.14 CDJ62299.1 - 0.39 10.6 17.3 0.24 11.3 6.8 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TCP PF03634.13 CDJ62299.1 - 0.4 11.2 16.9 0.14 12.7 7.0 2.4 2 0 0 2 2 2 0 TCP family transcription factor DUF1980 PF09323.10 CDJ62299.1 - 0.76 9.7 9.4 0.59 10.0 0.9 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF1980) DUF2828 PF11443.8 CDJ62299.1 - 1.2 7.1 10.0 0.34 8.9 3.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) APG5 PF04106.12 CDJ62299.1 - 1.6 8.3 5.5 0.64 9.6 2.8 1.6 2 0 0 2 2 2 0 Autophagy protein Apg5 RR_TM4-6 PF06459.12 CDJ62299.1 - 1.6 8.5 13.7 0.098 12.5 1.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MCU PF04678.13 CDJ62299.1 - 3.2 7.8 15.1 3.2 7.8 4.8 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter EMC3_TMCO1 PF01956.16 CDJ62299.1 - 5.3 6.7 10.3 0.29 10.9 2.0 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SID-1_RNA_chan PF13965.6 CDJ62299.1 - 5.6 5.2 6.0 4.1 5.7 3.3 2.0 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 CDJ62299.1 - 6.1 5.0 26.1 0.59 8.3 12.4 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 CDJ62299.1 - 8 6.2 12.0 23 4.7 0.1 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain EIIBC-GUT_N PF03612.14 CDJ62299.1 - 8.6 6.1 13.3 13 5.4 0.7 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus CPSF100_C PF13299.6 CDJ62299.1 - 9.6 6.4 13.8 7.9 6.6 1.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RskA PF10099.9 CDJ62300.1 - 0.00011 22.6 0.2 0.00011 22.6 0.2 9.2 1 1 5 7 7 7 1 Anti-sigma-K factor rskA RskA PF10099.9 CDJ62301.1 - 0.0049 17.2 0.0 0.0049 17.2 0.0 6.2 1 1 4 6 6 6 1 Anti-sigma-K factor rskA Sec62 PF03839.16 CDJ62302.1 - 4.1e-36 124.5 23.5 2e-21 76.5 15.5 2.4 2 0 0 2 2 2 2 Translocation protein Sec62 FA_desaturase PF00487.24 CDJ62302.1 - 0.12 12.2 0.2 0.12 12.2 0.2 3.4 2 1 2 4 4 4 0 Fatty acid desaturase PsbI PF02532.14 CDJ62303.1 - 0.041 13.8 0.6 0.08 12.9 0.6 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) RVP_2 PF08284.11 CDJ62306.1 - 7.7e-12 45.1 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ62306.1 - 3.9e-10 40.2 0.0 7.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ62306.1 - 6e-10 39.6 0.0 1.7e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ62306.1 - 0.00012 21.9 0.0 0.0015 18.3 0.0 2.4 3 0 0 3 3 3 1 Aspartyl protease RVP PF00077.20 CDJ62306.1 - 0.00048 20.4 0.0 0.0048 17.2 0.0 2.5 2 1 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 CDJ62306.1 - 0.005 17.1 0.2 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF3552 PF12072.8 CDJ62306.1 - 0.13 11.6 0.7 0.23 10.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) RVT_1 PF00078.27 CDJ62307.1 - 4.1e-17 62.4 0.0 8.2e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ62307.1 - 6.1e-17 61.9 0.0 1.1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ62307.1 - 1e-07 31.7 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 CDJ62307.1 - 0.076 12.8 0.6 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 Integrase core domain zf-CCCH PF00642.24 CDJ62308.1 - 9.5e-08 31.8 14.4 0.00014 21.6 3.0 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ62308.1 - 0.00013 21.6 8.9 0.0071 16.1 3.1 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CDJ62308.1 - 0.00045 20.9 0.0 0.00045 20.9 0.0 4.6 4 2 0 4 4 4 2 Torus domain zf_CCCH_4 PF18345.1 CDJ62308.1 - 0.0011 19.0 18.1 0.0034 17.4 1.7 3.7 4 1 0 4 4 4 2 Zinc finger domain zf-CCCH_3 PF15663.5 CDJ62308.1 - 0.66 10.2 12.2 0.076 13.2 0.9 3.1 2 1 1 3 3 3 0 Zinc-finger containing family LMBR1 PF04791.16 CDJ62308.1 - 1.7 7.5 3.7 2.9 6.7 3.7 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Sec62 PF03839.16 CDJ62308.1 - 1.9 7.9 6.4 8.7 5.8 6.4 2.1 1 0 0 1 1 1 0 Translocation protein Sec62 zf-CCCH_2 PF14608.6 CDJ62308.1 - 2.1 8.9 7.2 5.6 7.6 1.7 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Hist_deacetyl PF00850.19 CDJ62309.1 - 3.4e-58 197.6 0.0 6.5e-58 196.6 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Ank_2 PF12796.7 CDJ62309.1 - 3.5e-10 40.3 0.2 1.3e-06 28.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ62309.1 - 5.2e-09 36.2 2.3 3.4e-07 30.4 0.2 3.6 3 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ62309.1 - 3.9e-07 30.5 5.4 0.012 16.1 0.3 4.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ62309.1 - 2.5e-06 27.4 1.1 1.2 10.0 0.1 4.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CDJ62309.1 - 0.00063 20.1 0.5 0.00063 20.1 0.5 4.3 4 0 0 4 4 4 2 Ankyrin repeat DDRGK PF09756.9 CDJ62310.1 - 1.1e-42 145.7 13.3 1.1e-42 145.7 13.3 2.5 2 1 1 3 3 3 1 DDRGK domain BAF1_ABF1 PF04684.13 CDJ62310.1 - 0.00087 18.5 8.9 0.0012 18.0 8.9 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor RskA PF10099.9 CDJ62310.1 - 0.0016 18.7 13.8 0.0034 17.7 9.2 2.2 1 1 1 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ62310.1 - 0.015 15.4 7.0 0.015 15.3 7.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HemN_C PF06969.16 CDJ62310.1 - 0.021 14.9 1.2 0.35 10.9 0.5 3.0 2 1 1 3 3 3 0 HemN C-terminal domain SARAF PF06682.12 CDJ62310.1 - 0.13 11.8 8.1 0.22 11.1 8.1 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SR-25 PF10500.9 CDJ62310.1 - 0.78 9.3 21.2 1.5 8.3 21.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Shisa PF13908.6 CDJ62310.1 - 3.4 7.9 7.2 35 4.6 7.0 2.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator YjbH PF06082.11 CDJ62310.1 - 5.7 5.6 11.4 7.2 5.3 11.4 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Trp_oprn_chp PF09534.10 CDJ62310.1 - 8.9 6.1 25.8 5 6.9 0.6 2.2 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NatB_MDM20 PF09797.9 CDJ62312.1 - 0.0056 15.7 0.8 0.014 14.3 0.8 1.6 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 CDJ62312.1 - 0.024 15.4 2.0 21 6.2 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SRP40_C PF05022.12 CDJ62314.1 - 2.6e-23 82.7 0.8 2.6e-23 82.7 0.8 2.4 2 0 0 2 2 2 1 SRP40, C-terminal domain RE_Eco47II PF09553.10 CDJ62314.1 - 0.039 13.5 0.5 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Eco47II restriction endonuclease Trypan_PARP PF05887.11 CDJ62314.1 - 0.23 11.4 11.1 0.44 10.5 11.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Apt1 PF10351.9 CDJ62314.1 - 1.1 8.0 11.4 1.2 7.9 11.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SLC12 PF03522.15 CDJ62314.1 - 1.9 7.5 12.8 1.9 7.4 12.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Hydin_ADK PF17213.3 CDJ62314.1 - 2.3 8.5 13.8 3.8 7.7 13.8 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Raftlin PF15250.6 CDJ62314.1 - 2.9 6.5 13.8 3.2 6.4 13.8 1.2 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 CDJ62314.1 - 3 6.5 15.9 3.1 6.5 15.9 1.2 1 0 0 1 1 1 0 Presenilin SOBP PF15279.6 CDJ62314.1 - 3.6 8.1 7.7 4 8.0 7.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Hid1 PF12722.7 CDJ62314.1 - 4.4 5.3 15.7 4.6 5.2 15.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 CDJ62314.1 - 7.7 5.6 9.4 8.7 5.5 9.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.5 CDJ62314.1 - 9.3 3.2 12.1 9.5 3.2 12.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SR-25 PF10500.9 CDJ62316.1 - 0.00071 19.3 5.6 0.00097 18.8 5.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ62316.1 - 0.051 11.7 6.5 0.056 11.6 6.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GREB1 PF15782.5 CDJ62316.1 - 0.14 9.3 0.5 0.15 9.2 0.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF755 PF05501.11 CDJ62316.1 - 0.25 11.6 13.2 0.47 10.7 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Herpes_pp85 PF04637.12 CDJ62316.1 - 0.67 8.3 1.6 0.84 8.0 1.6 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF1635 PF07795.11 CDJ62316.1 - 1.1 9.1 6.5 1.5 8.6 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) TFIIA PF03153.13 CDJ62316.1 - 1.9 8.4 9.7 2.4 8.0 9.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ62316.1 - 2.3 7.7 4.8 2.9 7.4 4.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RskA PF10099.9 CDJ62316.1 - 2.6 8.3 19.7 3.8 7.8 17.0 2.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ62317.1 - 0.18 11.9 13.2 0.51 10.4 13.2 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ62317.1 - 0.24 11.0 11.0 0.38 10.3 11.0 1.2 1 0 0 1 1 1 0 Spt20 family AAA_23 PF13476.6 CDJ62317.1 - 0.43 11.0 0.0 0.43 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF4834 PF16118.5 CDJ62317.1 - 0.88 10.6 4.3 1.8 9.6 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ62318.1 - 0.0079 15.0 31.5 0.011 14.6 31.5 1.3 1 0 0 1 1 1 1 Presenilin Caldesmon PF02029.15 CDJ62318.1 - 0.75 8.5 30.8 0.85 8.3 30.8 1.1 1 0 0 1 1 1 0 Caldesmon RIFIN PF02009.16 CDJ62318.1 - 3.1 7.6 23.6 3.7 7.3 23.6 1.1 1 0 0 1 1 1 0 Rifin XRN_M PF17846.1 CDJ62318.1 - 3.9 6.3 19.5 4.8 6.0 19.5 1.3 1 0 0 1 1 1 0 Xrn1 helical domain PAT1 PF09770.9 CDJ62318.1 - 5.2 5.2 57.8 6.3 4.9 57.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 CDJ62318.1 - 6 5.8 33.1 7.3 5.5 33.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDK5_activator PF03261.15 CDJ62318.1 - 6.2 6.3 26.1 7 6.1 26.1 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SPX PF03105.19 CDJ62318.1 - 7.7 6.3 29.3 8.6 6.2 29.3 1.1 1 0 0 1 1 1 0 SPX domain WD40 PF00400.32 CDJ62319.1 - 7.5e-05 23.4 7.6 0.17 12.8 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat TFIIA PF03153.13 CDJ62319.1 - 0.27 11.2 18.5 0.43 10.5 18.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 CDJ62321.1 - 1.6e-30 104.6 14.9 3e-08 34.2 0.2 9.1 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ62321.1 - 0.00019 21.7 0.1 13 6.1 0.0 5.0 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ62321.1 - 0.00028 20.0 0.0 0.075 12.0 0.0 3.2 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SPX PF03105.19 CDJ62321.1 - 0.024 14.6 4.1 0.079 12.9 4.1 1.8 1 1 0 1 1 1 0 SPX domain Hira PF07569.11 CDJ62321.1 - 0.094 12.4 0.2 2.2 7.9 0.0 2.7 2 1 0 2 2 2 0 TUP1-like enhancer of split SR-25 PF10500.9 CDJ62321.1 - 3.3 7.2 44.4 0.22 11.1 18.0 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein TAF4 PF05236.14 CDJ62321.1 - 3.5 7.3 11.6 5.7 6.6 3.7 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family RskA PF10099.9 CDJ62322.1 - 2.1 8.6 17.6 2.5 8.4 17.6 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA zf-MYND PF01753.18 CDJ62323.1 - 2.2e-12 46.9 12.2 4e-12 46.0 12.2 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CDJ62323.1 - 0.03 14.6 12.3 0.13 12.5 12.3 2.1 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Hen1_Lam_C PF18441.1 CDJ62323.1 - 0.091 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Hen1 La-motif C-terminal domain Ac76 PF05814.11 CDJ62324.1 - 0.033 14.2 0.7 0.083 12.9 0.7 1.6 1 0 0 1 1 1 0 Orf76 (Ac76) Apc15p PF05841.11 CDJ62324.1 - 0.045 14.5 38.7 0.046 14.5 3.1 4.2 4 0 0 4 4 4 0 Apc15p protein Ferlin_C PF16165.5 CDJ62324.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.7 3 0 0 3 3 3 0 Ferlin C-terminus Gaa1 PF04114.14 CDJ62324.1 - 0.9 8.5 6.8 0.058 12.4 0.4 2.1 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component RskA PF10099.9 CDJ62325.1 - 0.0036 17.6 8.9 0.0036 17.6 8.9 12.7 5 5 3 8 8 8 2 Anti-sigma-K factor rskA PWWP PF00855.17 CDJ62325.1 - 0.033 14.6 0.0 0.033 14.6 0.0 4.8 3 1 0 3 3 3 0 PWWP domain Hydrolase_3 PF08282.12 CDJ62326.1 - 3.2e-31 109.0 0.0 1.4e-23 83.9 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ62326.1 - 1.7e-10 40.8 0.0 4e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 CDJ62326.1 - 0.014 15.5 0.1 0.039 14.0 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AIF_C PF14721.6 CDJ62327.1 - 0.026 14.9 7.1 0.032 14.6 7.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4824 PF16106.5 CDJ62327.1 - 0.061 12.6 11.3 0.068 12.4 11.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) SpoIIP PF07454.11 CDJ62327.1 - 0.15 11.5 9.9 0.16 11.4 9.9 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pex14_N PF04695.13 CDJ62327.1 - 0.21 12.2 18.4 0.23 12.1 18.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_28 PF13521.6 CDJ62327.1 - 0.32 11.2 6.5 0.36 11.1 6.5 1.1 1 0 0 1 1 1 0 AAA domain Lipase_GDSL_3 PF14606.6 CDJ62327.1 - 0.37 10.9 4.8 0.4 10.8 4.8 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Presenilin PF01080.17 CDJ62327.1 - 0.78 8.4 11.4 0.72 8.5 11.4 1.0 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.14 CDJ62327.1 - 0.92 9.2 10.4 1 9.1 10.4 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SPT16 PF08644.11 CDJ62327.1 - 0.93 9.7 10.4 0.95 9.6 10.4 1.1 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) TERB2 PF15101.6 CDJ62327.1 - 1.5 8.8 18.5 1.5 8.8 18.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 eIF-3_zeta PF05091.12 CDJ62327.1 - 1.6 7.6 16.0 1.6 7.6 16.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 CDJ62327.1 - 1.7 7.6 8.0 1.7 7.6 8.0 1.0 1 0 0 1 1 1 0 CLN3 protein Ureide_permease PF07168.11 CDJ62327.1 - 1.8 7.2 4.0 1.7 7.3 4.0 1.0 1 0 0 1 1 1 0 Ureide permease OATP PF03137.20 CDJ62327.1 - 1.9 6.7 4.9 2 6.6 4.9 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1980 PF09323.10 CDJ62327.1 - 2 8.3 9.4 2.1 8.2 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) TFIIA PF03153.13 CDJ62327.1 - 2.1 8.3 35.6 2 8.3 35.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tmem26 PF09772.9 CDJ62327.1 - 2.2 7.5 9.1 2.7 7.3 9.1 1.0 1 0 0 1 1 1 0 Transmembrane protein 26 Band_3_cyto PF07565.13 CDJ62327.1 - 2.3 8.0 11.8 2.4 7.9 11.8 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Exonuc_VII_L PF02601.15 CDJ62327.1 - 2.6 7.5 16.2 2.8 7.4 16.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit EOS1 PF12326.8 CDJ62327.1 - 2.8 7.8 5.0 2.8 7.8 5.0 1.1 1 0 0 1 1 1 0 N-glycosylation protein Suf PF05843.14 CDJ62327.1 - 3.8 7.4 16.6 4.8 7.1 16.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ALMT PF11744.8 CDJ62327.1 - 3.9 6.2 8.9 4 6.2 8.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter EPL1 PF10513.9 CDJ62327.1 - 4.2 7.7 13.0 4.4 7.7 13.0 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like CSG2 PF16965.5 CDJ62327.1 - 4.5 6.1 6.5 4.6 6.1 6.5 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator MMR1 PF08505.10 CDJ62327.1 - 5 7.3 16.8 4.9 7.4 16.8 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PAT1 PF09770.9 CDJ62327.1 - 5.2 5.2 24.0 5.2 5.2 24.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PepSY_TM PF03929.16 CDJ62327.1 - 5.8 6.5 7.9 6.1 6.4 7.9 1.0 1 0 0 1 1 1 0 PepSY-associated TM region Ctr PF04145.15 CDJ62327.1 - 6.1 7.5 6.5 6.6 7.3 6.5 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Pex26 PF07163.12 CDJ62327.1 - 6.7 5.9 16.6 7.7 5.7 16.6 1.0 1 0 0 1 1 1 0 Pex26 protein Neur_chan_memb PF02932.16 CDJ62327.1 - 6.8 6.7 8.9 6.8 6.7 8.9 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDM10 PF12519.8 CDJ62327.1 - 6.8 5.4 9.9 7.2 5.3 9.9 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Kei1 PF08552.11 CDJ62327.1 - 7.6 6.4 8.2 8.6 6.2 8.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2722 PF10846.8 CDJ62327.1 - 7.7 5.3 31.9 11 4.8 31.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) HemX PF04375.14 CDJ62327.1 - 8.9 5.5 31.4 9.7 5.4 31.4 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase PCNA_N PF00705.18 CDJ62328.1 - 8.3e-45 151.6 5.0 3.9e-44 149.4 2.6 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CDJ62328.1 - 7.1e-28 97.3 0.0 5e-27 94.6 0.0 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CDJ62328.1 - 6.3e-07 29.1 1.3 2.3e-05 24.0 1.3 2.1 1 1 0 1 1 1 1 Rad9 Metallophos PF00149.28 CDJ62330.1 - 3.1e-32 112.7 0.0 5.1e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pribosyltran PF00156.27 CDJ62330.1 - 1.4e-07 31.2 0.0 2.2e-05 24.0 0.0 3.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain SR-25 PF10500.9 CDJ62330.1 - 1.8e-05 24.5 12.1 1.8e-05 24.5 12.1 9.0 5 2 1 6 6 6 1 Nuclear RNA-splicing-associated protein DUF3169 PF11368.8 CDJ62330.1 - 2.9 7.3 0.0 2.9 7.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) SAP PF02037.27 CDJ62331.1 - 4.1e-09 36.0 0.0 7.3e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 SAP domain VIR_N PF15912.5 CDJ62331.1 - 2.9 7.4 9.6 3.9 7.0 9.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Ten_N PF06484.12 CDJ62331.1 - 2.9 7.7 15.2 3.4 7.5 15.2 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region FAM76 PF16046.5 CDJ62332.1 - 0.042 13.2 10.5 0.06 12.7 10.5 1.1 1 0 0 1 1 1 0 FAM76 protein Hamartin PF04388.12 CDJ62332.1 - 0.14 10.8 10.8 0.16 10.6 10.8 1.2 1 0 0 1 1 1 0 Hamartin protein DUF2859 PF11072.8 CDJ62332.1 - 0.37 10.5 8.7 1.2 8.8 8.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2859) CLN3 PF02487.17 CDJ62332.1 - 4.1 6.3 5.6 5.9 5.8 5.6 1.2 1 0 0 1 1 1 0 CLN3 protein PAT1 PF09770.9 CDJ62332.1 - 5 5.3 19.1 6.2 4.9 19.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.13 CDJ62332.1 - 7 5.6 16.5 1.4 7.9 8.5 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Hid1 PF12722.7 CDJ62332.1 - 9.5 4.2 12.1 12 3.8 12.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CIAPIN1 PF05093.13 CDJ62333.1 - 0.00022 21.7 6.9 0.025 15.1 4.3 2.5 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis OxoDH_E1alpha_N PF12573.8 CDJ62333.1 - 0.19 11.5 1.0 1.5 8.6 0.6 2.6 2 1 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal ATP-sulfurylase PF01747.17 CDJ62334.1 - 1.2e-47 162.2 0.0 1.9e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 CDJ62334.1 - 2.5e-41 141.2 0.6 1.2e-20 74.0 0.0 3.3 2 1 0 2 2 2 2 Adenylylsulphate kinase PUA_2 PF14306.6 CDJ62334.1 - 9.1e-31 106.7 0.0 1.3e-29 102.9 0.0 2.2 1 1 0 1 1 1 1 PUA-like domain Pap_E4 PF02711.14 CDJ62334.1 - 0.11 13.5 5.9 2.4 9.2 2.0 2.6 2 0 0 2 2 2 0 E4 protein MgtE PF01769.16 CDJ62334.1 - 0.3 11.5 3.8 0.64 10.4 3.8 1.5 1 0 0 1 1 1 0 Divalent cation transporter ACDC PF14733.6 CDJ62335.1 - 1.8e-22 79.4 0.8 4.4e-22 78.2 0.2 2.0 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ62335.1 - 3.6e-05 23.9 4.9 3.6e-05 23.9 4.9 2.0 2 0 0 2 2 2 1 AP2 domain ANAPC_CDC26 PF10471.9 CDJ62335.1 - 0.11 13.3 12.4 0.34 11.8 2.9 3.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Laminin_G_3 PF13385.6 CDJ62336.1 - 1.1e-07 32.2 0.0 2.7e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 CDJ62336.1 - 0.023 15.3 0.0 0.066 13.8 0.0 1.8 2 0 0 2 2 2 0 Laminin G domain DnaJ PF00226.31 CDJ62340.1 - 2.4e-08 33.9 0.2 6.6e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain DUF5302 PF17227.2 CDJ62340.1 - 0.13 13.2 0.5 0.13 13.2 0.5 3.4 4 0 0 4 4 4 0 Family of unknown function (DUF5302) TFIIA PF03153.13 CDJ62340.1 - 0.15 12.0 9.8 0.17 11.8 9.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PITH PF06201.13 CDJ62342.1 - 2.5e-17 63.5 0.0 3.9e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 PITH domain Cas_Csn2 PF09711.10 CDJ62343.1 - 0.026 14.2 1.5 0.068 12.8 1.5 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) LETM1 PF07766.13 CDJ62344.1 - 1.5e-81 273.6 3.0 1.5e-81 273.6 3.0 2.6 3 0 0 3 3 3 1 LETM1-like protein HAD_2 PF13419.6 CDJ62344.1 - 0.16 12.1 0.5 0.82 9.7 0.1 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Surface_antigen PF11054.8 CDJ62346.1 - 6.8e-147 487.6 16.6 5.4e-74 248.9 5.3 2.2 2 0 0 2 2 2 2 Sporozoite TA4 surface antigen Transglut_C PF00927.22 CDJ62346.1 - 0.0024 18.0 0.5 1.7 8.8 0.1 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Surface_antigen PF11054.8 CDJ62347.1 - 4.6e-74 249.2 3.2 6.1e-74 248.8 3.2 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62348.1 - 1.8e-74 250.5 1.2 2.7e-74 249.9 1.2 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF2950 PF11453.8 CDJ62348.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Transglut_C PF00927.22 CDJ62348.1 - 0.23 11.6 0.1 0.45 10.7 0.1 1.4 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Surface_antigen PF11054.8 CDJ62349.1 - 5.4e-76 255.5 2.7 6.6e-76 255.2 2.7 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62350.1 - 1.7e-73 247.3 5.1 2.1e-73 247.0 5.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62351.1 - 3.8e-77 259.3 6.5 4.6e-77 259.0 6.5 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62353.1 - 2.1e-78 263.4 4.5 2.5e-78 263.1 4.5 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62354.1 - 1.4e-78 264.0 5.5 1.9e-78 263.5 5.5 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Transglut_C PF00927.22 CDJ62354.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain ABC_tran PF00005.27 CDJ62355.1 - 2.1e-32 112.5 0.0 3.9e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CDJ62355.1 - 5.6e-22 78.7 9.6 1.1e-21 77.8 9.6 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CDJ62355.1 - 9.9e-05 21.9 0.0 0.0011 18.4 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ62355.1 - 0.00057 20.3 0.4 0.0017 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 CDJ62355.1 - 0.00075 19.4 0.0 0.0065 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 CDJ62355.1 - 0.0033 16.6 0.0 0.0063 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CDJ62355.1 - 0.0068 16.7 0.0 0.037 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CDJ62355.1 - 0.01 15.1 1.0 0.024 13.9 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 CDJ62355.1 - 0.017 14.8 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CDJ62355.1 - 0.034 13.9 0.0 0.081 12.6 0.0 1.8 2 1 0 2 2 2 0 AAA domain ABC_membrane_2 PF06472.15 CDJ62355.1 - 0.05 13.0 1.7 0.083 12.3 1.7 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 NACHT PF05729.12 CDJ62355.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DEAD PF00270.29 CDJ62355.1 - 0.092 12.5 0.1 1.1 9.0 0.1 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 CDJ62355.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase DLIC PF05783.11 CDJ62355.1 - 0.24 10.2 0.0 0.24 10.2 0.0 1.9 2 0 0 2 2 1 0 Dynein light intermediate chain (DLIC) AAA_15 PF13175.6 CDJ62355.1 - 0.26 11.0 0.0 0.38 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Apt1 PF10351.9 CDJ62355.1 - 0.9 8.3 4.0 1.6 7.5 4.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 CDJ62355.1 - 2.7 7.1 9.4 4.4 6.4 9.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein ATP-synt_S1 PF05827.12 CDJ62356.1 - 0.038 13.8 1.1 0.046 13.5 0.6 1.3 1 1 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) TMEM52 PF14979.6 CDJ62356.1 - 0.038 13.9 0.2 0.043 13.7 0.2 1.2 1 0 0 1 1 1 0 Transmembrane 52 L51_S25_CI-B8 PF05047.16 CDJ62357.1 - 0.00036 20.4 0.0 0.00067 19.5 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF547 PF04784.14 CDJ62357.1 - 0.093 12.8 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF547 DAGAT PF03982.13 CDJ62358.1 - 1.2e-29 103.1 0.0 2.1e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Pkinase PF00069.25 CDJ62359.1 - 1.8e-66 224.2 0.0 2.6e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ62359.1 - 1.8e-32 112.6 0.0 2.9e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ62359.1 - 1.2e-05 24.8 0.1 7.1e-05 22.3 0.1 2.2 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDJ62359.1 - 9.1e-05 21.6 0.3 9.1e-05 21.6 0.3 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CDJ62359.1 - 0.0029 17.0 0.6 0.0066 15.8 0.6 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5320 PF17253.2 CDJ62359.1 - 0.05 14.7 1.0 0.11 13.5 1.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5320) APH PF01636.23 CDJ62359.1 - 0.092 12.6 3.8 2.2 8.2 0.0 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family SpoIIP PF07454.11 CDJ62360.1 - 0.46 9.9 3.5 0.9 8.9 3.5 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ADSL_C PF10397.9 CDJ62362.1 - 0.044 14.3 1.4 0.38 11.3 0.2 2.3 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminus RTTN_N PF14726.6 CDJ62362.1 - 0.064 14.1 2.3 2.7 8.9 1.5 2.5 1 1 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Phosducin PF02114.16 CDJ62362.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Phosducin Myb_DNA-bind_6 PF13921.6 CDJ62363.1 - 2.7e-06 27.5 0.9 4.5e-06 26.8 0.9 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CDJ62363.1 - 0.00041 20.5 0.2 0.00062 19.9 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CDJ62363.1 - 0.0011 19.2 0.6 0.0016 18.6 0.6 1.2 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 CDJ62363.1 - 0.054 13.5 0.1 0.086 12.9 0.1 1.3 1 0 0 1 1 1 0 SLIDE TMEM65 PF10507.9 CDJ62364.1 - 1.2e-26 92.8 2.0 1.2e-26 92.8 2.0 5.0 5 1 0 5 5 5 2 Transmembrane protein 65 Fra10Ac1 PF09725.9 CDJ62365.1 - 9.9e-18 64.4 11.8 9.9e-18 64.4 11.8 2.6 2 1 0 2 2 2 1 Folate-sensitive fragile site protein Fra10Ac1 NAM-associated PF14303.6 CDJ62365.1 - 0.0012 19.5 1.1 0.0012 19.5 1.1 10.9 5 4 5 10 10 10 1 No apical meristem-associated C-terminal domain PAP1 PF08601.10 CDJ62367.1 - 3 7.5 31.9 4.2 7.0 31.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Tmemb_cc2 PF10267.9 CDJ62367.1 - 3.8 6.5 14.8 4.6 6.3 14.8 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein GREB1 PF15782.5 CDJ62367.1 - 9 3.3 28.5 10 3.1 28.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2807 PF10988.8 CDJ62368.1 - 0.24 11.2 7.0 0.3 10.9 7.0 1.1 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain TFIIA PF03153.13 CDJ62368.1 - 2.9 7.8 25.3 3.1 7.7 25.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Helicase_C PF00271.31 CDJ62369.1 - 2.1e-20 73.1 0.1 2.9e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain VAD1-2 PF15310.6 CDJ62369.1 - 0.06 13.2 0.0 7.2 6.4 0.0 2.0 2 0 0 2 2 2 0 Vitamin A-deficiency (VAD) rat model signalling Pex14_N PF04695.13 CDJ62370.1 - 0.0037 17.9 22.1 0.0037 17.9 22.1 1.9 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CobT PF06213.12 CDJ62370.1 - 0.14 11.5 28.3 0.072 12.5 25.2 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT MMR1 PF08505.10 CDJ62370.1 - 0.23 11.7 23.2 0.33 11.2 23.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein V_ATPase_I PF01496.19 CDJ62370.1 - 0.26 9.2 14.1 0.31 8.9 14.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Velvet PF11754.8 CDJ62370.1 - 0.32 10.9 14.6 0.46 10.4 14.6 1.2 1 0 0 1 1 1 0 Velvet factor DDHD PF02862.17 CDJ62370.1 - 0.33 11.1 13.4 0.61 10.2 13.4 1.5 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ62370.1 - 0.41 9.6 21.7 0.53 9.2 21.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF572 PF04502.13 CDJ62370.1 - 0.55 9.8 22.3 0.79 9.3 22.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAT1 PF09770.9 CDJ62370.1 - 1.1 7.5 31.6 1.4 7.1 31.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ABC2_membrane_2 PF12679.7 CDJ62370.1 - 1.5 8.0 5.2 2.9 7.1 5.2 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein SLC12 PF03522.15 CDJ62370.1 - 1.5 7.8 18.4 2 7.4 18.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 TFIIA PF03153.13 CDJ62370.1 - 1.5 8.7 50.3 0.084 12.9 44.9 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ62370.1 - 1.6 8.5 23.2 2.5 7.9 23.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ62370.1 - 1.8 7.3 12.6 2.3 6.9 12.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 CDJ62370.1 - 1.9 8.5 14.5 2.8 7.9 14.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ62370.1 - 2 8.3 24.0 2.9 7.8 24.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.7 CDJ62370.1 - 2.1 6.4 18.1 2.6 6.0 18.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 CDJ62370.1 - 2.3 6.7 17.8 3 6.3 17.8 1.1 1 0 0 1 1 1 0 Macoilin family SID-1_RNA_chan PF13965.6 CDJ62370.1 - 2.5 6.4 5.8 3.3 6.0 5.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Membralin PF09746.9 CDJ62370.1 - 2.6 7.0 8.8 3.3 6.6 8.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF5427 PF10310.9 CDJ62370.1 - 3.1 6.7 25.7 4.4 6.2 25.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SpoIIP PF07454.11 CDJ62370.1 - 5 6.5 22.1 7.2 6.0 22.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) VIR_N PF15912.5 CDJ62370.1 - 6.6 6.3 13.3 12 5.4 13.3 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Lin-8 PF03353.15 CDJ62370.1 - 7.2 6.1 24.0 9.9 5.6 24.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Peptidase_S15 PF02129.18 CDJ62370.1 - 7.5 6.0 16.1 13 5.2 16.1 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) RPA43_OB PF17875.1 CDJ62370.1 - 7.6 7.2 13.1 14 6.3 13.1 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I FAM60A PF15396.6 CDJ62370.1 - 7.7 6.5 18.1 12 5.8 18.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A NARP1 PF12569.8 CDJ62370.1 - 8.3 5.2 22.6 11 4.8 22.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Smg8_Smg9 PF10220.9 CDJ62370.1 - 8.6 4.5 19.9 10 4.2 19.9 1.1 1 0 0 1 1 1 0 Smg8_Smg9 GREB1 PF15782.5 CDJ62370.1 - 8.6 3.3 25.7 10 3.1 25.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NEMP PF10225.9 CDJ62370.1 - 9.8 5.8 5.8 14 5.2 5.8 1.2 1 0 0 1 1 1 0 NEMP family Pox_Ag35 PF03286.14 CDJ62370.1 - 9.8 5.9 19.2 17 5.1 19.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Atg8 PF02991.16 CDJ62372.1 - 8.6e-33 112.6 0.1 1.5e-32 111.8 0.1 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CDJ62372.1 - 2.6e-05 24.5 0.1 7.5e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2722 PF10846.8 CDJ62373.1 - 0.00025 20.1 6.8 0.00025 20.1 6.8 7.9 4 3 2 6 6 6 2 Protein of unknown function (DUF2722) NPR1_interact PF15699.5 CDJ62373.1 - 0.0056 17.3 1.5 0.0056 17.3 1.5 6.5 8 0 0 8 8 8 1 NPR1 interacting PH PF00169.29 CDJ62373.1 - 0.078 13.5 0.0 25 5.4 0.0 2.6 2 0 0 2 2 2 0 PH domain RskA PF10099.9 CDJ62375.1 - 0.0063 16.8 20.1 0.0063 16.8 20.1 2.6 3 1 0 3 3 3 1 Anti-sigma-K factor rskA Senescence_reg PF04520.13 CDJ62376.1 - 0.0006 20.7 2.0 0.00088 20.1 2.0 1.2 1 0 0 1 1 1 1 Senescence regulator TFIIA PF03153.13 CDJ62376.1 - 0.00088 19.4 7.5 0.00088 19.4 7.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ62376.1 - 0.17 11.5 7.2 0.21 11.2 7.2 1.2 1 0 0 1 1 1 0 Spt20 family FAM199X PF15814.5 CDJ62376.1 - 0.51 9.4 7.9 0.86 8.6 7.9 1.3 1 0 0 1 1 1 0 Protein family FAM199X MITF_TFEB_C_3_N PF15951.5 CDJ62376.1 - 1.9 9.1 16.1 0.17 12.5 7.6 2.2 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus FoP_duplication PF13865.6 CDJ62377.1 - 0.003 18.1 0.0 0.0042 17.6 0.0 1.2 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Ribosomal_60s PF00428.19 CDJ62377.1 - 0.065 13.8 5.8 0.068 13.8 5.8 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ala_racemase_N PF01168.20 CDJ62378.1 - 3.9e-18 65.9 1.1 3.9e-18 65.9 1.1 2.1 1 1 1 2 2 2 1 Alanine racemase, N-terminal domain DUF5635 PF18685.1 CDJ62378.1 - 2.8 8.0 0.0 2.8 8.0 0.0 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5635) GT87 PF09594.10 CDJ62379.1 - 8.8e-06 25.6 5.6 1.9e-05 24.5 5.6 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 87 DNA_primase_S PF01896.19 CDJ62379.1 - 7.3e-05 22.9 0.0 0.026 14.6 0.0 2.6 1 1 1 2 2 2 2 DNA primase small subunit EIF4E-T PF10477.9 CDJ62379.1 - 0.046 12.6 16.9 0.069 12.0 16.9 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RskA PF10099.9 CDJ62379.1 - 0.15 12.3 38.4 0.095 13.0 21.3 3.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA SUA5 PF03481.13 CDJ62379.1 - 0.5 10.9 10.4 0.22 12.1 5.7 2.4 2 1 0 2 2 2 0 Putative GTP-binding controlling metal-binding DUF5320 PF17253.2 CDJ62379.1 - 5 8.3 13.0 2.1 9.4 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5320) SR-25 PF10500.9 CDJ62380.1 - 2.2 7.9 24.6 2.8 7.5 24.6 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ62380.1 - 2.5 6.1 18.1 2.4 6.1 18.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Apt1 PF10351.9 CDJ62380.1 - 6.1 5.6 6.4 5.7 5.7 6.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pex26 PF07163.12 CDJ62380.1 - 9.5 5.4 14.0 12 5.1 14.0 1.1 1 0 0 1 1 1 0 Pex26 protein MFS_1 PF07690.16 CDJ62381.1 - 0.0037 16.3 4.2 0.0037 16.3 4.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TFIIA PF03153.13 CDJ62381.1 - 0.12 12.4 11.4 0.3 11.0 3.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ62381.1 - 5.1 6.9 25.0 1.7 8.5 0.8 2.2 2 0 0 2 2 2 0 SPX domain SR-25 PF10500.9 CDJ62382.1 - 0.51 9.9 2.5 0.93 9.1 2.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ62383.1 - 0.012 15.9 12.0 0.016 15.5 12.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA HTH_42 PF06224.12 CDJ62383.1 - 0.024 14.2 4.3 0.025 14.1 4.3 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain ERbeta_N PF12497.8 CDJ62383.1 - 0.037 13.8 6.9 0.12 12.1 4.7 2.0 2 0 0 2 2 2 0 Estrogen receptor beta DUF4179 PF13786.6 CDJ62383.1 - 0.42 11.1 0.1 0.42 11.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Presenilin PF01080.17 CDJ62383.1 - 0.81 8.4 6.9 0.87 8.3 6.9 1.0 1 0 0 1 1 1 0 Presenilin Ribosomal_L2_C PF03947.18 CDJ62383.1 - 0.83 9.9 3.8 1.5 9.0 3.8 1.4 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain TFIIA PF03153.13 CDJ62383.1 - 1 9.3 11.6 1.1 9.1 11.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ62383.1 - 1.4 8.4 17.1 1.8 8.1 17.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Serinc PF03348.15 CDJ62383.1 - 1.5 7.6 4.6 1.7 7.5 4.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1631 PF07793.11 CDJ62383.1 - 2.1 6.7 17.4 2.3 6.5 17.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) RNA_pol_Rpc4 PF05132.14 CDJ62383.1 - 4 7.8 10.3 9.6 6.6 10.3 1.7 1 1 0 1 1 1 0 RNA polymerase III RPC4 MGC-24 PF05283.11 CDJ62383.1 - 9.9 6.6 11.4 29 5.1 11.4 1.7 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SPX PF03105.19 CDJ62384.1 - 0.0041 17.1 9.9 0.05 13.5 9.9 2.1 1 1 0 1 1 1 1 SPX domain 4HBT_2 PF13279.6 CDJ62385.1 - 0.057 13.9 0.0 0.068 13.7 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF2184 PF09950.9 CDJ62385.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2184) 4HBT PF03061.22 CDJ62385.1 - 0.14 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Pkinase PF00069.25 CDJ62387.1 - 1e-34 120.2 0.0 1.4e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ62387.1 - 1e-19 70.9 0.0 2e-19 69.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ62387.1 - 0.00081 18.8 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CDJ62387.1 - 0.0052 16.7 2.0 0.022 14.7 2.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ62387.1 - 0.0063 15.9 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CDJ62387.1 - 0.04 13.6 0.1 0.13 11.9 0.0 1.9 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 CDJ62387.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF3446 PF11928.8 CDJ62387.1 - 1.3 9.4 16.9 0.27 11.6 0.7 3.3 3 0 0 3 3 3 0 Early growth response N-terminal domain DUF1645 PF07816.11 CDJ62387.1 - 1.7 9.2 10.4 12 6.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ62387.1 - 10 5.7 11.8 9.7 5.7 10.7 1.4 2 0 0 2 2 2 0 Spt20 family Utp14 PF04615.13 CDJ62389.1 - 0.34 9.4 46.5 0.43 9.1 46.5 1.0 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 CDJ62389.1 - 5.7 3.9 44.2 6.9 3.6 44.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4521 PF15021.6 CDJ62390.1 - 0.015 15.3 0.3 0.018 15.0 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) DUF3043 PF11241.8 CDJ62390.1 - 0.043 13.8 0.3 0.043 13.8 0.3 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Presenilin PF01080.17 CDJ62390.1 - 0.057 12.2 0.2 0.072 11.8 0.2 1.1 1 0 0 1 1 1 0 Presenilin Herpes_DNAp_acc PF04929.12 CDJ62390.1 - 0.37 9.7 3.7 0.43 9.5 3.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor YebO PF13974.6 CDJ62390.1 - 1.8 8.7 6.3 4.7 7.4 6.3 1.8 1 1 0 1 1 1 0 YebO-like protein OCC1 PF15506.6 CDJ62390.1 - 2.2 8.5 5.9 3.7 7.7 2.7 2.4 2 1 0 2 2 2 0 OCC1 family Collagen PF01391.18 CDJ62391.1 - 1.1e-08 34.7 31.5 1.1e-08 34.7 31.5 6.5 6 0 0 6 6 6 1 Collagen triple helix repeat (20 copies) DnaJ PF00226.31 CDJ62392.1 - 4.5e-15 55.5 0.0 2.4e-14 53.2 0.0 2.1 1 1 0 1 1 1 1 DnaJ domain Snf7 PF03357.21 CDJ62393.1 - 0.029 14.0 1.0 0.047 13.3 1.0 1.4 1 0 0 1 1 1 0 Snf7 zf-CCHC PF00098.23 CDJ62396.1 - 4.1e-05 23.5 9.9 0.0055 16.7 0.9 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ62396.1 - 0.18 11.7 4.2 0.96 9.3 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CDJ62396.1 - 0.21 11.9 4.6 0.58 10.6 4.4 1.8 1 1 0 1 1 1 0 DnaJ central domain SUI1 PF01253.22 CDJ62399.1 - 1.4e-24 86.4 0.4 2.1e-24 85.8 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 HA2 PF04408.23 CDJ62400.1 - 4e-26 91.4 0.1 2e-25 89.2 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ62400.1 - 2e-22 79.4 0.0 4.4e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ62400.1 - 6.5e-10 39.3 0.0 1.5e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CDJ62400.1 - 1e-07 32.2 0.1 2.3e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 CDJ62400.1 - 6.4e-06 26.0 0.1 1.7e-05 24.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ62400.1 - 3.2e-05 24.2 0.0 0.00011 22.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ62400.1 - 0.00088 19.0 0.2 0.0047 16.7 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CDJ62400.1 - 0.0023 18.3 0.0 0.0059 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDJ62400.1 - 0.0085 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 CDJ62400.1 - 0.013 14.6 0.4 0.047 12.7 0.2 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 CDJ62400.1 - 0.026 14.0 0.6 0.14 11.6 0.2 2.2 2 0 0 2 2 2 0 PhoH-like protein Microtub_bd PF16796.5 CDJ62400.1 - 0.11 12.5 0.0 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Microtubule binding AAA_16 PF13191.6 CDJ62400.1 - 8.6 6.7 8.1 0.44 10.9 0.1 2.8 4 0 0 4 4 3 0 AAA ATPase domain Pkinase PF00069.25 CDJ62401.1 - 1.6e-52 178.5 0.0 1.6e-50 171.9 0.0 3.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ62401.1 - 8.4e-35 120.3 0.1 2e-32 112.5 0.0 3.1 2 1 0 2 2 2 1 Protein tyrosine kinase EF-hand_11 PF08976.11 CDJ62401.1 - 3.6e-05 24.6 0.0 0.00016 22.5 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain Myb_DNA-binding PF00249.31 CDJ62404.1 - 8.7e-24 83.5 0.0 7.5e-09 35.6 0.0 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ62404.1 - 1.1e-15 57.5 0.0 0.00017 21.7 0.0 3.9 2 1 1 3 3 3 3 Myb-like DNA-binding domain Retrotran_gag_2 PF14223.6 CDJ62405.1 - 0.016 14.8 2.8 0.018 14.7 2.2 1.4 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type Sec20 PF03908.13 CDJ62405.1 - 0.031 14.2 3.5 0.035 14.0 3.5 1.1 1 0 0 1 1 1 0 Sec20 Vps51 PF08700.11 CDJ62405.1 - 0.037 14.1 6.7 0.35 11.0 0.9 2.2 1 1 1 2 2 2 0 Vps51/Vps67 OmpH PF03938.14 CDJ62405.1 - 0.042 14.2 12.9 0.06 13.7 12.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF16 PF01519.16 CDJ62405.1 - 0.049 14.1 5.2 0.068 13.7 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Sulfatase_C PF14707.6 CDJ62405.1 - 0.054 14.2 2.6 0.073 13.8 2.6 1.1 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase H-kinase_dim PF02895.14 CDJ62405.1 - 0.13 12.7 3.2 0.25 11.8 3.2 1.5 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain TMPIT PF07851.13 CDJ62405.1 - 0.13 11.4 3.6 0.15 11.3 3.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 CDJ62405.1 - 0.2 10.9 6.6 0.23 10.8 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_23 PF13476.6 CDJ62405.1 - 0.93 10.0 7.5 1.2 9.6 7.5 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 CDJ62405.1 - 1.7 6.5 6.3 1.8 6.4 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GTA_holin_3TM PF11351.8 CDJ62405.1 - 5.2 7.6 8.6 9.7 6.8 8.6 1.6 1 1 0 1 1 1 0 Holin of 3TMs, for gene-transfer release eIF_4EBP PF05456.11 CDJ62406.1 - 0.45 10.5 8.3 0.96 9.4 8.3 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) TFB6 PF17110.5 CDJ62406.1 - 0.53 10.0 4.8 0.67 9.7 4.8 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH EIIBC-GUT_N PF03612.14 CDJ62406.1 - 1.3 8.7 7.0 2 8.1 7.0 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TFIIA PF03153.13 CDJ62406.1 - 4.1 7.3 36.3 5.5 6.9 36.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ62406.1 - 5.2 6.7 8.5 8 6.1 8.5 1.4 1 0 0 1 1 1 0 Connexin Yip1 PF04893.17 CDJ62407.1 - 0.019 14.7 0.1 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 Yip1 domain Ribosomal_60s PF00428.19 CDJ62407.1 - 0.13 12.9 1.8 0.35 11.5 1.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein WD40 PF00400.32 CDJ62408.1 - 4e-21 74.9 7.5 2.7e-06 28.0 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ62408.1 - 1.6e-12 47.5 0.0 0.0025 18.1 0.0 4.9 3 3 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CDJ62408.1 - 0.0082 15.7 0.1 0.22 11.1 0.1 2.1 1 1 1 2 2 2 2 PQQ-like domain Ge1_WD40 PF16529.5 CDJ62408.1 - 0.012 14.6 2.1 0.78 8.6 1.6 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ62408.1 - 0.14 10.8 0.2 0.32 9.6 0.2 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Dehydrin PF00257.19 CDJ62409.1 - 0.031 14.8 7.4 0.041 14.5 7.4 1.2 1 0 0 1 1 1 0 Dehydrin Spt20 PF12090.8 CDJ62409.1 - 0.32 10.6 12.3 0.33 10.5 12.3 1.1 1 0 0 1 1 1 0 Spt20 family FAM70 PF14967.6 CDJ62409.1 - 0.54 9.7 5.5 0.57 9.6 5.5 1.1 1 0 0 1 1 1 0 FAM70 protein TFIIA PF03153.13 CDJ62409.1 - 2.3 8.1 19.2 2.6 7.9 19.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RtcB PF01139.17 CDJ62411.1 - 7.1e-46 157.2 0.2 8.2e-42 143.8 0.1 2.1 1 1 1 2 2 2 2 tRNA-splicing ligase RtcB DUF58 PF01882.18 CDJ62412.1 - 0.0065 16.7 1.9 0.016 15.5 1.9 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF58 RskA PF10099.9 CDJ62412.1 - 0.025 14.9 15.9 0.05 13.9 15.9 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA ADP_ribosyl_GH PF03747.14 CDJ62412.1 - 0.089 12.5 2.9 0.11 12.2 2.9 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase TFIIA PF03153.13 CDJ62412.1 - 0.38 10.7 38.5 0.47 10.4 38.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ62412.1 - 0.68 9.5 23.1 5.4 6.6 23.0 1.8 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein PPP4R2 PF09184.11 CDJ62412.1 - 5.4 6.5 10.9 5.9 6.4 10.9 1.0 1 0 0 1 1 1 0 PPP4R2 Dehydrin PF00257.19 CDJ62412.1 - 6.5 7.3 21.9 1.5 9.3 4.8 2.1 1 1 1 2 2 2 0 Dehydrin DUF2791 PF10923.8 CDJ62414.1 - 0.046 12.6 7.2 0.026 13.4 1.4 2.3 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) DUF1072 PF06380.11 CDJ62414.1 - 0.22 11.4 2.8 1.1 9.1 2.8 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) DJ-1_PfpI PF01965.24 CDJ62415.1 - 0.0034 17.2 0.0 0.0091 15.8 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family Thioredoxin_3 PF13192.6 CDJ62415.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Methyltr_RsmB-F PF01189.17 CDJ62416.1 - 4.8e-14 52.5 5.1 2.5e-07 30.5 0.1 3.4 3 1 0 3 3 3 2 16S rRNA methyltransferase RsmB/F GTP_EFTU PF00009.27 CDJ62417.1 - 5.6e-41 140.2 0.0 1.9e-40 138.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CDJ62417.1 - 1.2e-30 105.8 0.0 4.2e-30 104.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 CDJ62417.1 - 1.6e-29 101.8 0.0 3.1e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CDJ62417.1 - 1.2e-23 82.9 0.1 3e-23 81.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDJ62417.1 - 6.3e-13 48.9 0.3 1.6e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CDJ62417.1 - 0.0048 16.7 0.0 0.0048 16.7 0.0 1.9 3 0 0 3 3 3 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CDJ62418.1 - 6.5e-13 48.8 0.0 1.7e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ62418.1 - 1.7e-09 37.5 0.0 6e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CDJ62418.1 - 1.4e-07 31.1 0.4 0.00013 21.4 0.1 2.5 2 0 0 2 2 2 2 Bacterial TniB protein AAA_16 PF13191.6 CDJ62418.1 - 0.00018 21.9 3.5 0.00049 20.5 3.5 1.8 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ62418.1 - 0.0026 17.7 0.2 0.19 11.7 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 CDJ62418.1 - 0.031 13.8 0.0 0.58 9.7 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B Septin PF00735.18 CDJ62418.1 - 0.055 12.7 0.1 0.26 10.6 0.1 2.0 1 1 0 1 1 1 0 Septin ECH_2 PF16113.5 CDJ62419.1 - 1.6e-86 290.8 0.9 3.6e-71 240.4 0.0 2.4 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CDJ62419.1 - 4.9e-23 81.7 0.1 4.5e-22 78.6 0.0 2.3 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase CCDC53 PF10152.9 CDJ62419.1 - 0.04 14.3 3.1 0.085 13.3 3.1 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex K_channel_TID PF07941.11 CDJ62419.1 - 1.7 9.1 8.6 4.6 7.8 8.6 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain TFIIA PF03153.13 CDJ62419.1 - 2.8 7.8 10.5 5.6 6.8 1.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pro_isomerase PF00160.21 CDJ62420.1 - 1.9e-49 167.9 0.1 6e-49 166.3 0.1 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CDJ62420.1 - 5e-09 36.6 1.6 0.56 11.2 0.0 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-C3HC4_3 PF13920.6 CDJ62421.1 - 1.8e-09 37.3 13.9 2.7e-09 36.7 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ62421.1 - 0.0024 18.2 14.0 0.0041 17.4 14.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ62421.1 - 0.096 12.5 14.4 0.19 11.6 14.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 CDJ62421.1 - 0.51 10.0 13.3 1.4 8.6 6.9 2.3 1 1 1 2 2 2 0 P-11 zinc finger EMP24_GP25L PF01105.24 CDJ62422.1 - 3.3e-35 121.7 0.0 4.2e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Tna_leader PF08053.11 CDJ62422.1 - 0.52 10.4 4.1 4.1 7.5 0.8 2.7 2 0 0 2 2 2 0 Tryptophanase operon leader peptide HEAT PF02985.22 CDJ62423.1 - 3.2e-06 26.9 13.2 0.037 14.3 0.0 8.1 7 0 0 7 7 7 2 HEAT repeat Importin_rep_6 PF18829.1 CDJ62423.1 - 0.0015 18.6 0.0 0.0044 17.1 0.0 1.7 1 0 0 1 1 1 1 Importin repeat 6 NopRA1 PF16201.5 CDJ62423.1 - 0.0029 17.2 5.4 21 4.6 0.0 5.1 5 1 1 6 6 6 3 Nucleolar pre-ribosomal-associated protein 1 HEAT_2 PF13646.6 CDJ62423.1 - 0.021 15.2 1.6 0.021 15.2 1.6 7.4 6 2 3 9 9 9 0 HEAT repeats HEAT_EZ PF13513.6 CDJ62423.1 - 0.23 12.0 32.1 2.5 8.7 0.0 9.0 10 0 0 10 10 10 0 HEAT-like repeat Importin_rep_4 PF18808.1 CDJ62423.1 - 3.3 8.1 9.5 10 6.5 0.0 4.7 3 2 1 4 4 4 0 Importin repeat PfkB PF00294.24 CDJ62424.1 - 5.3e-44 150.7 0.2 4.6e-38 131.2 0.1 2.4 2 1 0 2 2 2 2 pfkB family carbohydrate kinase NAD_Gly3P_dh_N PF01210.23 CDJ62426.1 - 2.2e-41 141.5 0.0 3.4e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CDJ62426.1 - 9e-38 129.8 0.1 1.5e-37 129.1 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CDJ62426.1 - 0.12 13.0 0.0 1.2 9.8 0.0 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf-CCHC PF00098.23 CDJ62427.1 - 1.2e-07 31.4 11.6 3.5e-06 26.8 2.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ62427.1 - 0.0023 17.7 0.5 0.0023 17.7 0.5 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ62427.1 - 0.0069 16.3 0.3 0.0069 16.3 0.3 2.5 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ62427.1 - 0.011 15.4 6.3 0.015 15.0 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ62427.1 - 0.024 14.5 2.1 0.024 14.5 2.1 2.3 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CDJ62427.1 - 0.072 13.5 5.8 0.15 12.4 5.8 1.5 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_5 PF14787.6 CDJ62427.1 - 3.9 7.3 9.9 2 8.2 1.3 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DEAD PF00270.29 CDJ62428.1 - 1.5e-11 44.3 0.0 3.2e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RskA PF10099.9 CDJ62428.1 - 7.8e-05 23.0 8.5 0.00015 22.1 8.5 1.6 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ62428.1 - 0.0013 17.8 9.0 0.0013 17.8 9.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) CD34_antigen PF06365.12 CDJ62428.1 - 0.0052 16.4 0.3 1.5 8.4 0.3 2.3 2 0 0 2 2 2 2 CD34/Podocalyxin family CAF1 PF04857.20 CDJ62428.1 - 0.039 13.1 0.0 0.043 13.0 0.0 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF3464 PF11947.8 CDJ62428.1 - 0.05 13.4 0.2 0.083 12.6 0.2 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF3347 PF11827.8 CDJ62428.1 - 0.11 12.7 3.5 0.23 11.6 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) UPF0560 PF10577.9 CDJ62428.1 - 0.61 8.5 5.8 0.87 8.0 5.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3304 PF11745.8 CDJ62428.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF3304) Suf PF05843.14 CDJ62428.1 - 1.7 8.5 9.7 0.034 14.1 3.4 1.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1180 PF06679.12 CDJ62428.1 - 4.5 7.6 11.1 0.085 13.3 4.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DSPc PF00782.20 CDJ62429.1 - 1.3e-11 44.4 0.0 2.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CBM_20 PF00686.19 CDJ62429.1 - 7.6e-05 22.5 0.0 0.0032 17.4 0.0 2.5 2 0 0 2 2 2 1 Starch binding domain DivIVA PF05103.13 CDJ62429.1 - 0.036 14.2 0.0 0.099 12.7 0.0 1.6 2 0 0 2 2 2 0 DivIVA protein Y_phosphatase PF00102.27 CDJ62429.1 - 0.041 13.4 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF442 PF04273.13 CDJ62429.1 - 0.049 13.7 0.1 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Ribosomal_L22e PF01776.17 CDJ62431.1 - 2.6e-44 150.0 3.1 3.2e-44 149.8 3.1 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family AMPK1_CBM PF16561.5 CDJ62431.1 - 0.019 15.2 0.0 0.062 13.5 0.0 1.8 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase pP_pnuc_1 PF18165.1 CDJ62431.1 - 0.027 14.3 0.8 2.9 7.8 0.0 2.1 1 1 1 2 2 2 0 Predicted pPIWI-associating nuclease DUF3228 PF11539.8 CDJ62432.1 - 1.3e-81 272.8 0.0 1.5e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) eIF3_p135 PF12807.7 CDJ62433.1 - 3.3e-08 33.8 0.0 1.5e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 CDJ62433.1 - 0.056 13.7 3.8 0.9 9.9 0.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PWI PF01480.17 CDJ62434.1 - 1.9e-28 98.6 0.0 3.1e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 PWI domain PYC_OADA PF02436.18 CDJ62434.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain CALM_bind PF16025.5 CDJ62434.1 - 0.05 14.1 0.7 0.1 13.1 0.7 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding DIRP PF06584.13 CDJ62434.1 - 0.056 13.6 0.2 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 DIRP PhoD PF09423.10 CDJ62438.1 - 1.2e-13 50.9 1.7 2.8e-12 46.3 1.7 2.4 1 1 0 1 1 1 1 PhoD-like phosphatase DUF4757 PF15949.5 CDJ62438.1 - 0.0082 16.6 4.4 0.026 15.0 1.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4757) Peptidase_M78 PF06114.13 CDJ62438.1 - 0.039 13.9 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain TerD PF02342.18 CDJ62439.1 - 2.4e-05 23.9 0.0 0.0002 20.9 0.0 2.4 3 0 0 3 3 3 1 TerD domain LXG PF04740.12 CDJ62439.1 - 0.018 14.8 0.6 0.049 13.3 0.6 1.7 1 0 0 1 1 1 0 LXG domain of WXG superfamily Spc7 PF08317.11 CDJ62439.1 - 0.023 13.6 0.1 0.038 12.9 0.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Dynamitin PF04912.14 CDJ62439.1 - 0.05 12.9 4.6 0.25 10.7 2.0 2.1 1 1 0 2 2 2 0 Dynamitin Baculo_PEP_C PF04513.12 CDJ62439.1 - 0.13 12.3 0.3 0.3 11.1 0.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BCAS2 PF05700.11 CDJ62439.1 - 0.13 11.9 1.2 0.22 11.2 0.2 1.7 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) ABC_tran_CTD PF16326.5 CDJ62439.1 - 1.2 9.5 3.9 1.8 8.9 1.4 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain DSS1_SEM1 PF05160.13 CDJ62440.1 - 0.014 15.5 22.5 0.54 10.4 22.5 2.3 1 1 0 1 1 1 0 DSS1/SEM1 family FAM193_C PF15914.5 CDJ62440.1 - 5.6 6.8 5.9 3.1 7.6 0.1 2.2 2 0 0 2 2 2 0 FAM193 family C-terminal DEAD PF00270.29 CDJ62441.1 - 3.5e-39 134.4 0.0 6.2e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ62441.1 - 6.1e-18 65.2 0.0 1.3e-16 60.9 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Rhomboid PF01694.22 CDJ62443.1 - 3.9e-17 62.6 4.0 3.9e-17 62.6 4.0 2.0 3 0 0 3 3 3 1 Rhomboid family DUF1751 PF08551.10 CDJ62443.1 - 0.048 14.2 0.4 0.093 13.3 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) YbjQ_1 PF01906.17 CDJ62444.1 - 5.4e-19 68.8 0.5 7.9e-19 68.2 0.5 1.3 1 0 0 1 1 1 1 Putative heavy-metal-binding Tad PF13400.6 CDJ62444.1 - 1.3 9.4 7.6 3.5 8.0 7.6 1.7 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Pkinase PF00069.25 CDJ62445.1 - 2e-39 135.5 0.0 4.1e-37 128.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ62445.1 - 5.9e-23 81.5 0.0 8.6e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ62445.1 - 6.1e-08 32.3 0.0 1.3e-07 31.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDJ62445.1 - 6.7e-06 25.1 0.0 8.4e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ62445.1 - 5.6e-05 23.2 0.6 0.00017 21.6 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family RsgA_GTPase PF03193.16 CDJ62447.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Radical_SAM PF04055.21 CDJ62448.1 - 1.8e-16 61.0 0.0 6.6e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 CDJ62448.1 - 4.5e-15 55.5 0.3 4.5e-15 55.5 0.3 2.6 2 1 0 2 2 2 1 Uncharacterized protein family UPF0004 DUF1450 PF07293.11 CDJ62448.1 - 0.033 14.0 0.1 8.7 6.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) VPS13_C PF16909.5 CDJ62449.1 - 1.4e-24 86.8 0.7 2.5e-20 73.0 0.0 2.9 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CDJ62449.1 - 4.1e-05 23.5 0.0 0.0017 18.2 0.0 2.9 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal ATG_C PF09333.11 CDJ62449.1 - 5.5e-05 23.4 0.0 0.00018 21.8 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain SUIM_assoc PF16619.5 CDJ62450.1 - 0.31 11.1 8.7 1.8 8.7 8.7 2.3 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SSP160 PF06933.11 CDJ62450.1 - 2.9 6.0 5.2 4.1 5.5 5.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PGA2 PF07543.12 CDJ62450.1 - 2.9 7.9 8.3 2.4 8.1 0.1 3.0 3 0 0 3 3 3 0 Protein trafficking PGA2 AAA_2 PF07724.14 CDJ62452.1 - 5.8e-52 176.2 0.0 1e-47 162.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CDJ62452.1 - 2e-31 108.0 0.6 2e-31 108.0 0.6 3.1 1 1 2 3 3 3 1 AAA lid domain AAA PF00004.29 CDJ62452.1 - 6.4e-26 91.3 0.0 4.7e-14 52.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDJ62452.1 - 4.7e-24 84.2 2.1 4.7e-24 84.2 2.1 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 CDJ62452.1 - 2.8e-20 72.2 3.7 4.2e-11 42.8 0.1 2.9 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 CDJ62452.1 - 2.1e-19 69.9 0.0 8.9e-14 51.7 0.0 3.7 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ62452.1 - 1.7e-12 48.1 3.8 1.5e-05 25.5 0.0 5.3 3 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 CDJ62452.1 - 8.9e-09 35.7 1.0 0.0007 19.9 0.0 4.7 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 CDJ62452.1 - 9.3e-08 32.0 0.0 1.7e-05 24.6 0.0 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CDJ62452.1 - 1.6e-07 31.4 0.0 0.011 15.8 0.0 3.4 3 1 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 CDJ62452.1 - 4e-07 29.9 0.1 0.13 11.9 0.0 3.9 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.6 CDJ62452.1 - 7.2e-07 29.8 0.0 0.0088 16.6 0.0 3.4 3 0 0 3 3 2 2 AAA domain TniB PF05621.11 CDJ62452.1 - 1e-06 28.3 0.0 0.0077 15.7 0.0 3.8 2 1 0 2 2 2 1 Bacterial TniB protein ATPase_2 PF01637.18 CDJ62452.1 - 4.5e-05 23.5 2.2 2 8.3 0.0 4.5 4 1 0 6 6 4 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 CDJ62452.1 - 4.5e-05 23.4 0.3 2.5 8.0 0.0 3.5 3 0 0 3 3 3 1 RsgA GTPase AAA_7 PF12775.7 CDJ62452.1 - 4.8e-05 22.9 0.0 0.036 13.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RuvB_N PF05496.12 CDJ62452.1 - 0.00011 22.0 0.1 5.4 6.7 0.0 4.2 3 1 1 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CDJ62452.1 - 0.00013 22.0 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CDJ62452.1 - 0.00016 21.6 0.0 0.14 12.1 0.0 3.2 3 0 0 3 3 2 1 NACHT domain RNA_helicase PF00910.22 CDJ62452.1 - 0.00052 20.4 0.0 0.42 11.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Roc PF08477.13 CDJ62452.1 - 0.00053 20.2 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 CDJ62452.1 - 0.0015 18.7 1.0 0.84 9.8 0.0 4.1 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.12 CDJ62452.1 - 0.002 17.4 1.8 0.2 10.9 0.0 3.6 4 0 0 4 4 4 1 Zeta toxin Mg_chelatase PF01078.21 CDJ62452.1 - 0.0026 17.2 0.1 6.2 6.1 0.0 3.5 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CDJ62452.1 - 0.0059 17.0 0.2 0.34 11.2 0.0 3.4 4 0 0 4 4 2 1 AAA domain ABC_tran_CTD PF16326.5 CDJ62452.1 - 0.0075 16.5 4.8 0.0075 16.5 4.8 2.8 1 1 1 2 2 2 1 ABC transporter C-terminal domain NTPase_1 PF03266.15 CDJ62452.1 - 0.011 15.7 1.2 10 6.0 0.0 3.7 4 0 0 4 4 3 0 NTPase AAA_25 PF13481.6 CDJ62452.1 - 0.012 15.2 0.1 0.48 10.0 0.1 3.1 2 1 1 3 3 3 0 AAA domain ResIII PF04851.15 CDJ62452.1 - 0.013 15.5 0.0 0.8 9.7 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit MutS_III PF05192.18 CDJ62452.1 - 0.015 15.6 0.0 0.015 15.6 0.0 2.6 2 2 0 2 2 2 0 MutS domain III ABC_tran PF00005.27 CDJ62452.1 - 0.017 15.6 0.0 0.78 10.2 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_3 PF07726.11 CDJ62452.1 - 0.024 14.5 0.0 11 5.9 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 CDJ62452.1 - 0.036 13.9 0.1 0.97 9.2 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Bac_DnaA PF00308.18 CDJ62452.1 - 0.038 13.8 0.0 1.5 8.6 0.0 2.8 3 0 0 3 3 2 0 Bacterial dnaA protein AAA_24 PF13479.6 CDJ62452.1 - 0.048 13.4 0.0 12 5.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_6 PF12774.7 CDJ62452.1 - 0.057 12.4 0.1 0.33 9.9 0.0 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region SRP54 PF00448.22 CDJ62452.1 - 0.099 12.3 0.1 10 5.7 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 CDJ62452.1 - 0.11 12.2 0.0 23 4.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.6 CDJ62452.1 - 0.13 12.7 1.5 5.1 7.5 0.0 3.7 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 CDJ62452.1 - 0.17 12.1 6.8 3.6 7.8 0.0 3.6 4 1 0 4 4 2 0 AAA domain SPACA9 PF15120.6 CDJ62452.1 - 0.18 11.6 1.5 0.48 10.2 1.5 1.7 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 AAA_23 PF13476.6 CDJ62452.1 - 0.28 11.7 14.4 5.2 7.5 0.0 4.1 2 2 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ62452.1 - 0.42 10.3 5.3 16 5.1 0.0 4.1 3 1 0 3 3 2 0 AAA domain LUC7 PF03194.15 CDJ62452.1 - 1.1 8.8 4.7 2.3 7.8 4.7 1.5 1 0 0 1 1 1 0 LUC7 N_terminus GAD-like PF08887.11 CDJ62453.1 - 0.012 15.4 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 GAD-like domain Lactamase_B_2 PF12706.7 CDJ62454.1 - 1.8e-13 50.4 0.2 5.6e-09 35.8 0.1 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ62454.1 - 0.00012 22.2 0.0 0.00085 19.4 0.0 2.2 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Spt20 PF12090.8 CDJ62454.1 - 1.4 8.4 8.0 2.5 7.6 8.0 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ62454.1 - 3.8 7.4 10.5 0.48 10.4 4.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 CDJ62455.1 - 2.1 8.3 10.2 2.2 8.2 10.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ62456.1 - 0.017 13.8 24.3 0.02 13.6 24.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.6 CDJ62456.1 - 0.16 12.6 16.1 0.18 12.4 16.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SWI-SNF_Ssr4 PF08549.10 CDJ62456.1 - 0.18 10.4 16.2 0.19 10.3 16.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) RPA43_OB PF17875.1 CDJ62456.1 - 0.62 10.7 4.4 5.8 7.6 0.9 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Ribonuc_P_40 PF08584.11 CDJ62456.1 - 1.2 8.3 8.2 3.5 6.8 8.2 1.7 1 1 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit FliD_N PF02465.18 CDJ62456.1 - 1.6 9.5 17.5 4.2 8.1 5.5 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ndc1_Nup PF09531.10 CDJ62456.1 - 1.7 7.2 20.3 2.1 6.9 20.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 CDJ62456.1 - 1.8 6.8 19.5 2 6.6 19.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4551 PF15087.6 CDJ62456.1 - 2.9 6.6 13.4 3.4 6.4 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4578 PF15147.6 CDJ62456.1 - 3.5 8.5 15.1 3.3 8.6 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) Presenilin PF01080.17 CDJ62456.1 - 6.2 5.5 12.1 7.3 5.2 12.1 1.1 1 0 0 1 1 1 0 Presenilin AUX_IAA PF02309.16 CDJ62456.1 - 7.8 6.3 10.9 11 5.8 10.9 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF2367 PF10164.9 CDJ62456.1 - 8.6 6.9 10.3 4.1 8.0 2.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) WD40 PF00400.32 CDJ62457.1 - 0.0021 18.9 0.1 0.025 15.4 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat SUIM_assoc PF16619.5 CDJ62458.1 - 0.046 13.8 0.3 0.046 13.8 0.3 6.1 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF724 PF05266.14 CDJ62458.1 - 0.056 13.3 0.4 0.056 13.3 0.4 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF724) Pox_F11 PF04943.12 CDJ62458.1 - 0.11 11.5 0.4 0.23 10.5 0.4 1.4 1 0 0 1 1 1 0 Poxvirus F11 protein DUF4080 PF13311.6 CDJ62458.1 - 1 9.5 0.0 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4080) Phage_HK97_TLTM PF06120.11 CDJ62460.1 - 0.015 14.5 3.8 0.025 13.8 3.8 1.4 1 1 0 1 1 1 0 Tail length tape measure protein K-box PF01486.17 CDJ62460.1 - 0.68 10.1 12.3 0.67 10.2 9.0 2.4 2 1 0 2 2 2 0 K-box region DOR PF14839.6 CDJ62460.1 - 0.74 9.7 9.4 0.61 10.0 8.3 1.5 1 1 0 1 1 1 0 DOR family SUIM_assoc PF16619.5 CDJ62461.1 - 0.018 15.1 21.4 0.33 11.1 6.3 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Med15 PF09606.10 CDJ62461.1 - 0.076 11.7 20.3 0.076 11.7 20.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CDJ62461.1 - 0.91 8.4 8.4 1.5 7.7 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ62461.1 - 1 8.9 14.0 0.15 11.6 1.3 2.0 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ62462.1 - 3.9 7.0 74.5 0.095 12.3 28.4 3.3 2 2 1 3 3 3 0 Nuclear RNA-splicing-associated protein PSS PF03034.15 CDJ62463.1 - 0.001 18.9 1.7 0.003 17.4 0.1 2.1 1 1 1 2 2 2 1 Phosphatidyl serine synthase SR-25 PF10500.9 CDJ62463.1 - 0.0012 18.5 10.8 0.0016 18.1 10.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4551 PF15087.6 CDJ62463.1 - 0.023 13.6 10.1 0.03 13.2 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hamartin PF04388.12 CDJ62463.1 - 0.032 12.9 13.9 0.039 12.6 13.9 1.0 1 0 0 1 1 1 0 Hamartin protein VIR_N PF15912.5 CDJ62463.1 - 0.067 12.8 14.3 0.1 12.2 14.3 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CCSAP PF15748.5 CDJ62463.1 - 0.18 11.9 26.4 0.28 11.3 26.4 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 CDJ62463.1 - 0.4 9.4 15.5 0.71 8.6 15.5 1.4 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 CDJ62463.1 - 0.63 8.7 11.6 0.85 8.3 11.6 1.1 1 0 0 1 1 1 0 Raftlin XAP5 PF04921.14 CDJ62463.1 - 1.8 8.3 14.7 3.1 7.6 14.7 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator SLC12 PF03522.15 CDJ62463.1 - 2.4 7.1 14.8 3.1 6.7 14.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Alph_Pro_TM PF09608.10 CDJ62463.1 - 2.7 7.8 7.9 3.1 7.6 6.7 1.6 1 1 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Borrelia_P83 PF05262.11 CDJ62463.1 - 4.2 5.8 14.9 5 5.5 14.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_S64 PF08192.11 CDJ62463.1 - 8.5 4.7 10.6 13 4.2 10.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 LMBR1 PF04791.16 CDJ62463.1 - 8.9 5.1 10.4 14 4.4 10.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DAGK_acc PF00609.19 CDJ62466.1 - 4.5e-12 46.6 0.0 7.1e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CDJ62466.1 - 2.8e-11 43.1 1.3 4.1e-09 36.1 1.3 3.5 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ycf4 PF02392.16 CDJ62466.1 - 0.062 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Ycf4 ANAPC1 PF12859.7 CDJ62466.1 - 2.1 8.9 6.4 7 7.2 3.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 SPX PF03105.19 CDJ62466.1 - 2.5 7.9 8.7 2.1 8.2 4.5 2.2 2 0 0 2 2 2 0 SPX domain SUIM_assoc PF16619.5 CDJ62467.1 - 0.00031 20.7 56.7 0.06 13.4 5.2 5.7 5 0 0 5 5 5 4 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 CDJ62467.1 - 0.00058 19.2 2.8 0.00058 19.2 2.8 11.4 11 1 1 12 12 12 2 Mediator complex subunit 3 fungal AP2 PF00847.20 CDJ62467.1 - 0.0019 18.4 0.0 0.2 11.9 0.0 3.8 2 0 0 2 2 2 1 AP2 domain DUF2722 PF10846.8 CDJ62467.1 - 0.019 13.9 33.3 0.052 12.5 0.1 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ62467.1 - 6.1 6.4 55.4 0.71 9.4 8.0 4.4 4 0 0 4 4 4 0 Spt20 family Roughex PF06020.11 CDJ62469.1 - 3.2 6.8 18.8 3.3 6.7 4.6 2.5 2 0 0 2 2 2 0 Drosophila roughex protein OmpH PF03938.14 CDJ62469.1 - 7.7 6.9 24.4 2 8.8 7.6 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TCTP PF00838.17 CDJ62470.1 - 8.3e-54 182.4 1.5 9.3e-54 182.2 1.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein URO-D PF01208.17 CDJ62470.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) tRNA-synt_2b PF00587.25 CDJ62471.1 - 8.6e-23 81.2 0.0 1.4e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CDJ62471.1 - 3.9e-21 75.3 1.7 3.9e-21 75.3 1.7 2.3 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain SUIM_assoc PF16619.5 CDJ62471.1 - 3.2e-08 33.5 9.2 0.0011 19.0 0.7 2.7 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ62471.1 - 0.0017 17.4 11.2 0.027 13.5 1.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ62471.1 - 0.012 15.2 20.9 0.19 11.3 2.9 2.2 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ62471.1 - 0.16 12.0 15.6 0.096 12.7 1.9 2.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ62471.1 - 0.56 10.1 6.4 5.8 6.8 0.9 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4407 PF14362.6 CDJ62471.1 - 1 8.6 10.8 2.1 7.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) RAB3GAP2_N PF14655.6 CDJ62471.1 - 5.7 6.1 7.4 8.7 5.5 0.2 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FTZ PF03867.14 CDJ62471.1 - 6.2 6.3 7.8 6.2 6.3 0.6 2.2 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region RNA_pol_Rpb8 PF03870.15 CDJ62474.1 - 3.2e-38 131.1 0.0 3.6e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CDJ62474.1 - 5.2e-06 26.5 0.0 3.4e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 DNA-directed RNA polymerase, subunit G Pkinase PF00069.25 CDJ62476.1 - 8.8e-60 202.3 0.0 1.9e-59 201.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ62476.1 - 4.3e-30 104.9 0.0 8.5e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ62476.1 - 0.0038 16.1 0.0 0.0038 16.1 0.0 3.0 3 1 0 3 3 3 1 Fungal protein kinase E1-E2_ATPase PF00122.20 CDJ62477.1 - 6.4e-36 123.6 0.0 1.3e-34 119.3 0.0 2.8 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ62477.1 - 2.4e-13 50.8 4.3 1.9e-05 25.1 0.1 4.0 4 0 0 4 4 4 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ62477.1 - 5e-08 32.9 0.6 0.0029 17.7 0.0 3.1 3 0 0 3 3 3 2 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDJ62477.1 - 0.023 14.4 0.2 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SOAR PF16533.5 CDJ62478.1 - 2.3 8.2 7.6 0.38 10.7 1.1 2.1 2 0 0 2 2 2 0 STIM1 Orai1-activating region SUIM_assoc PF16619.5 CDJ62478.1 - 3.4 7.8 24.5 1.4 9.1 4.1 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ATPgrasp_ST PF14397.6 CDJ62479.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Rabaptin PF03528.15 CDJ62479.1 - 0.26 9.9 15.1 0.35 9.5 15.1 1.1 1 0 0 1 1 1 0 Rabaptin Exonuc_VII_L PF02601.15 CDJ62479.1 - 1.8 8.0 20.1 3.2 7.3 20.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 CDJ62479.1 - 4.9 7.4 22.3 24 5.1 22.3 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 RT_RNaseH PF17917.1 CDJ62483.1 - 5.8e-13 49.0 0.4 1.4e-12 47.8 0.4 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 CDJ62483.1 - 1.6e-11 43.9 0.0 3.6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CDJ62483.1 - 8.9e-10 38.8 0.8 7.9e-09 35.7 0.1 2.5 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ62483.1 - 8.8e-08 32.1 1.5 2.7e-07 30.6 1.5 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CDJ62483.1 - 8e-05 22.6 0.0 0.00019 21.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ62483.1 - 0.0049 16.7 0.1 0.016 15.0 0.1 1.9 1 0 0 1 1 1 1 Reverse transcriptase-like DUF1539 PF07560.11 CDJ62483.1 - 0.11 12.6 0.1 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) RVT_1 PF00078.27 CDJ62484.1 - 2.4e-05 24.0 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 CDJ62486.1 - 9.6e-10 38.2 0.0 2.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ62486.1 - 4.4e-09 36.1 0.0 8.8e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ62486.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Syntaxin-6_N PF09177.11 CDJ62486.1 - 7.9 7.1 9.2 94 3.7 0.1 3.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Radical_SAM PF04055.21 CDJ62487.1 - 0.00043 20.7 0.0 0.0047 17.3 0.0 2.4 1 1 1 3 3 3 1 Radical SAM superfamily HTH_1 PF00126.27 CDJ62487.1 - 0.04 13.9 0.0 0.6 10.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF4072 PF13284.6 CDJ62487.1 - 0.07 13.6 0.2 0.21 12.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) DUF908 PF06012.12 CDJ62488.1 - 2.4e-13 50.3 29.5 3.4e-13 49.7 0.0 5.7 6 0 0 6 6 6 3 Domain of Unknown Function (DUF908) DUF913 PF06025.12 CDJ62488.1 - 2.5e-11 43.2 9.4 1.1e-08 34.5 0.0 5.0 4 1 1 5 5 5 2 Domain of Unknown Function (DUF913) Mitofilin PF09731.9 CDJ62488.1 - 0.11 11.3 15.8 0.31 9.8 15.8 1.7 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HECT PF00632.25 CDJ62489.1 - 1.4e-91 307.2 0.0 2.2e-91 306.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 CDJ62489.1 - 8.5e-13 47.3 8.5 3.5e-09 35.8 1.9 7.2 6 1 0 6 6 6 3 Ubiquitin binding region UBA PF00627.31 CDJ62489.1 - 6.9e-10 38.6 0.1 2.2e-09 37.0 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain RVT_1 PF00078.27 CDJ62492.1 - 1.1e-36 126.5 0.0 1.9e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CDJ62492.1 - 4e-06 27.5 0.0 1.4e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-C2H2 PF00096.26 CDJ62492.1 - 0.01 16.2 0.9 0.01 16.2 0.9 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 CDJ62492.1 - 0.011 15.6 1.2 0.048 13.6 1.2 2.1 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 CDJ62492.1 - 0.027 15.3 0.7 0.027 15.3 0.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Sgf11 PF08209.11 CDJ62492.1 - 0.23 11.1 1.1 0.49 10.0 1.1 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Phage_min_cap2 PF06152.11 CDJ62492.1 - 0.63 8.9 7.1 0.42 9.5 4.9 1.7 2 0 0 2 2 2 0 Phage minor capsid protein 2 Rad50_zn_hook PF04423.14 CDJ62492.1 - 1.6 8.6 3.8 0.8 9.6 0.2 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif TFIIA PF03153.13 CDJ62493.1 - 0.001 19.2 41.0 0.044 13.8 15.0 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 CDJ62493.1 - 0.0074 16.0 9.0 0.012 15.3 2.8 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF572) AAA_23 PF13476.6 CDJ62493.1 - 0.32 11.5 7.9 0.53 10.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain DUF3744 PF12558.8 CDJ62493.1 - 1.7 9.5 6.0 13 6.6 1.7 2.3 2 0 0 2 2 2 0 ATP-binding cassette cobalt transporter SPX PF03105.19 CDJ62493.1 - 1.7 8.5 30.5 0.074 13.0 0.7 2.2 1 1 1 2 2 2 0 SPX domain RIFIN PF02009.16 CDJ62493.1 - 5 6.9 7.7 24 4.7 0.1 2.2 2 0 0 2 2 2 0 Rifin Spt20 PF12090.8 CDJ62493.1 - 9.9 5.7 31.4 2.2 7.8 12.4 2.3 2 0 0 2 2 2 0 Spt20 family Lactamase_B_2 PF12706.7 CDJ62494.1 - 5.1e-10 39.2 0.0 7.6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ62494.1 - 0.1 12.6 0.5 0.59 10.1 0.5 2.2 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily IMUP PF15761.5 CDJ62495.1 - 0.11 13.2 14.9 0.24 12.1 3.1 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein SOG2 PF10428.9 CDJ62495.1 - 0.11 11.6 7.9 0.13 11.4 7.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein IER PF05760.12 CDJ62496.1 - 0.07 13.4 18.1 0.09 13.1 18.1 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Zip PF02535.22 CDJ62496.1 - 0.52 9.5 3.6 0.63 9.2 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Sin_N PF04801.13 CDJ62496.1 - 1.7 7.8 20.6 2 7.5 20.6 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region PAT1 PF09770.9 CDJ62496.1 - 4.1 5.6 26.5 4.9 5.3 26.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 CDJ62496.1 - 4.3 7.2 36.6 5.4 6.9 36.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF913 PF06025.12 CDJ62496.1 - 5.9 5.8 9.2 8.4 5.3 9.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DRY_EERY PF09750.9 CDJ62496.1 - 6.1 7.1 12.5 8.3 6.7 12.5 1.2 1 0 0 1 1 1 0 Alternative splicing regulator SpoIIP PF07454.11 CDJ62496.1 - 6.7 6.1 13.8 9.4 5.6 13.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 CDJ62496.1 - 7.6 5.4 14.4 9.3 5.2 14.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CarboxypepD_reg PF13620.6 CDJ62497.1 - 0.00016 21.9 0.0 0.00091 19.5 0.3 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain TFIIA PF03153.13 CDJ62497.1 - 0.005 16.9 0.5 0.005 16.9 0.5 1.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ62497.1 - 0.011 15.8 6.0 0.011 15.8 6.0 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ62498.1 - 0.0072 16.0 2.5 0.0072 16.0 2.5 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ62498.1 - 1.6 9.4 11.4 0.81 10.4 6.2 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF755 PF05501.11 CDJ62498.1 - 7 6.9 11.6 3.3 8.0 9.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Chromo PF00385.24 CDJ62502.1 - 1.4e-10 40.9 0.1 3.1e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 CDJ62503.1 - 4.2e-21 74.9 0.0 1.1e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ62503.1 - 1.7e-20 73.3 0.0 4.9e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ62503.1 - 7.4e-06 25.6 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ62503.1 - 5.6e-05 23.2 0.5 0.00012 22.1 0.0 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain HTH_45 PF14947.6 CDJ62503.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DUF3365 PF11845.8 CDJ62505.1 - 1.7 9.0 5.8 1.9 8.8 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) PRP1_N PF06424.12 CDJ62506.1 - 0.0041 17.5 3.2 0.0041 17.5 3.2 4.0 2 1 0 2 2 2 1 PRP1 splicing factor, N-terminal Filament_head PF04732.14 CDJ62506.1 - 4.9 8.1 33.0 5.3 8.0 2.2 3.6 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region DDHD PF02862.17 CDJ62507.1 - 0.021 15.0 3.4 0.021 15.0 3.4 1.2 1 0 0 1 1 1 0 DDHD domain MMR1 PF08505.10 CDJ62507.1 - 0.11 12.8 9.1 0.12 12.6 9.1 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SAPS PF04499.15 CDJ62507.1 - 0.95 8.2 9.6 1.2 7.9 9.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UPF0560 PF10577.9 CDJ62507.1 - 1.5 7.2 10.7 2.1 6.7 10.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 V_ATPase_I PF01496.19 CDJ62507.1 - 1.6 6.6 7.0 1.6 6.5 7.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GREB1 PF15782.5 CDJ62507.1 - 6.7 3.7 7.1 6.9 3.6 7.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 CDJ62507.1 - 7.5 6.1 20.6 15 5.2 20.6 1.5 1 1 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 CDJ62507.1 - 8.3 5.3 14.7 10 4.9 14.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zn_peptidase PF04228.13 CDJ62508.1 - 0.0067 15.9 3.7 0.0079 15.7 3.7 1.0 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase IDO PF01231.18 CDJ62508.1 - 0.014 14.2 2.0 0.02 13.7 2.0 1.2 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase DUF3767 PF12597.8 CDJ62508.1 - 0.017 15.0 1.1 0.022 14.6 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) SHR3_chaperone PF08229.11 CDJ62508.1 - 0.018 14.0 4.0 0.022 13.7 4.0 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 DUF2076 PF09849.9 CDJ62508.1 - 0.03 14.4 9.8 0.03 14.4 9.8 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Period_C PF12114.8 CDJ62508.1 - 0.042 13.4 14.6 0.052 13.1 14.6 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Serinc PF03348.15 CDJ62508.1 - 0.12 11.2 1.7 0.14 11.1 1.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Suf PF05843.14 CDJ62508.1 - 0.17 11.8 4.1 0.18 11.8 4.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF5423 PF17461.2 CDJ62508.1 - 0.2 10.5 8.3 0.23 10.3 8.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5423) MscS_TM PF12794.7 CDJ62508.1 - 0.22 10.3 0.3 0.25 10.1 0.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Presenilin PF01080.17 CDJ62508.1 - 0.23 10.2 5.0 0.29 9.9 5.0 1.1 1 0 0 1 1 1 0 Presenilin SprA-related PF12118.8 CDJ62508.1 - 0.42 9.7 14.2 0.51 9.4 14.2 1.1 1 0 0 1 1 1 0 SprA-related family FAM199X PF15814.5 CDJ62508.1 - 0.55 9.2 12.7 0.61 9.1 12.7 1.1 1 0 0 1 1 1 0 Protein family FAM199X AIF_C PF14721.6 CDJ62508.1 - 0.85 10.0 5.8 0.29 11.5 2.5 1.8 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4834 PF16118.5 CDJ62508.1 - 1.3 10.0 15.4 0.064 14.2 8.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ62508.1 - 2.3 7.0 20.2 0.23 10.4 14.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Ribosomal_60s PF00428.19 CDJ62509.1 - 0.0063 17.1 2.9 0.0063 17.1 2.9 8.6 6 2 3 9 9 9 1 60s Acidic ribosomal protein SR-25 PF10500.9 CDJ62509.1 - 0.0073 15.9 5.3 0.0073 15.9 5.3 5.2 4 1 0 4 4 4 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ62511.1 - 0.33 10.5 24.1 0.36 10.4 3.6 2.1 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 CDJ62511.1 - 4.2 8.4 6.8 14 6.8 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CLN3 PF02487.17 CDJ62512.1 - 0.34 9.9 41.1 0.13 11.3 4.2 3.5 3 0 0 3 3 3 0 CLN3 protein DUF2722 PF10846.8 CDJ62513.1 - 5.3e-05 22.4 12.6 0.00011 21.4 12.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) U1snRNP70_N PF12220.8 CDJ62513.1 - 0.024 15.2 13.8 0.024 15.2 13.8 2.8 3 1 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PEHE PF15275.6 CDJ62513.1 - 0.14 12.8 10.2 0.31 11.7 10.2 1.5 1 0 0 1 1 1 0 PEHE domain Peroxin-13_N PF04088.13 CDJ62513.1 - 0.56 10.5 5.0 4.8 7.5 5.0 2.7 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4638 PF15472.6 CDJ62513.1 - 0.61 9.8 13.1 0.051 13.3 7.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) Ferlin_C PF16165.5 CDJ62513.1 - 0.64 10.0 3.5 1.7 8.6 3.5 1.7 1 0 0 1 1 1 0 Ferlin C-terminus Med26_C PF15693.5 CDJ62513.1 - 1.8 8.7 13.0 5.8 7.0 13.0 1.9 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal eIF-3_zeta PF05091.12 CDJ62513.1 - 1.9 7.4 15.8 3.6 6.5 15.8 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.13 CDJ62513.1 - 2.3 7.9 13.7 7.3 6.3 13.7 1.8 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Rrn6 PF10214.9 CDJ62513.1 - 3.1 6.2 20.8 8 4.8 20.8 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SCAI PF12070.8 CDJ62513.1 - 4 6.2 10.6 5.9 5.6 10.6 1.2 1 0 0 1 1 1 0 Protein SCAI Baculo_PP31 PF05311.11 CDJ62513.1 - 5.2 6.5 13.9 16 4.9 13.9 1.8 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Rxt3 PF08642.10 CDJ62513.1 - 7.7 7.3 7.1 78 4.1 7.1 2.7 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Spt20 PF12090.8 CDJ62514.1 - 0.12 11.9 10.4 0.13 11.9 10.4 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ62514.1 - 2.4 8.1 14.9 3 7.8 14.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3418 PF11898.8 CDJ62514.1 - 3.2 6.3 13.0 3.5 6.2 13.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) RLL PF10036.9 CDJ62514.1 - 4.8 7.0 11.0 5.8 6.7 11.0 1.1 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Kazal_2 PF07648.15 CDJ62515.1 - 3.9e-22 78.1 11.0 3.3e-11 43.1 3.1 3.9 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CDJ62515.1 - 1.8e-18 66.3 9.4 4.7e-10 39.3 4.7 2.8 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain RskA PF10099.9 CDJ62515.1 - 0.00014 22.2 2.4 0.00014 22.2 2.4 9.7 2 2 7 9 9 9 2 Anti-sigma-K factor rskA DUF2076 PF09849.9 CDJ62516.1 - 0.0062 16.6 1.9 0.0062 16.6 1.9 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) SUIM_assoc PF16619.5 CDJ62516.1 - 0.063 13.4 0.7 0.063 13.4 0.7 3.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Synaptobrevin PF00957.21 CDJ62517.1 - 4e-24 84.2 0.3 4e-24 84.2 0.3 1.9 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 CDJ62517.1 - 4e-19 68.4 0.1 1.1e-18 67.0 0.1 1.8 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF3446 PF11928.8 CDJ62517.1 - 0.079 13.3 11.0 5.7 7.3 12.1 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Miga PF10265.9 CDJ62517.1 - 0.13 11.2 5.6 0.23 10.4 5.6 1.3 1 0 0 1 1 1 0 Mitoguardin DUF1645 PF07816.11 CDJ62517.1 - 0.15 12.7 5.2 0.24 12.0 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) MCU PF04678.13 CDJ62517.1 - 0.22 11.6 1.5 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Sporozoite_P67 PF05642.11 CDJ62517.1 - 0.23 9.5 0.4 0.3 9.1 0.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Thioredoxin_4 PF13462.6 CDJ62517.1 - 0.28 11.3 3.2 0.68 10.1 3.2 1.6 1 0 0 1 1 1 0 Thioredoxin TFIIA PF03153.13 CDJ62517.1 - 0.31 11.0 11.0 0.48 10.4 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ62517.1 - 6.4 6.3 11.4 9.8 5.7 11.4 1.3 1 0 0 1 1 1 0 Spt20 family PTCRA PF15028.6 CDJ62518.1 - 1.1 8.9 7.9 0.48 10.1 0.8 2.1 1 1 1 2 2 2 0 Pre-T-cell antigen receptor CDK2AP PF09806.9 CDJ62518.1 - 1.2 9.1 16.8 0.85 9.6 2.4 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF755 PF05501.11 CDJ62519.1 - 0.0022 18.3 10.1 0.0022 18.3 10.1 10.1 8 2 2 10 10 10 4 Domain of unknown function (DUF755) RskA PF10099.9 CDJ62519.1 - 0.0094 16.3 9.4 0.0094 16.3 9.4 13.7 3 3 9 12 12 12 3 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ62520.1 - 0.0067 16.1 16.9 0.0067 16.1 16.9 5.8 4 2 1 5 5 5 1 Spt20 family RskA PF10099.9 CDJ62520.1 - 0.0088 16.4 10.5 0.0088 16.4 10.5 9.4 3 2 4 7 7 7 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ62520.1 - 0.049 13.7 0.6 0.049 13.7 0.6 8.7 6 3 2 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ62521.1 - 0.0012 19.1 7.9 0.0012 19.1 7.9 8.3 2 2 4 6 6 6 2 Anti-sigma-K factor rskA AAA_23 PF13476.6 CDJ62521.1 - 0.095 13.2 11.7 0.68 10.4 6.5 2.5 2 0 0 2 2 2 0 AAA domain Dala_Dala_lig_N PF01820.21 CDJ62521.1 - 0.31 11.5 2.1 0.55 10.7 0.2 2.3 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus SUIM_assoc PF16619.5 CDJ62522.1 - 0.0084 16.2 2.0 0.011 15.8 2.0 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Miga PF10265.9 CDJ62523.1 - 0.47 9.4 16.9 0.54 9.2 16.9 1.1 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 CDJ62523.1 - 0.55 8.7 18.6 0.78 8.2 18.6 1.3 1 0 0 1 1 1 0 Macoilin family Plasmodium_Vir PF05795.11 CDJ62523.1 - 1.5 8.2 10.2 2 7.8 10.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Draxin PF15550.6 CDJ62523.1 - 1.5 8.6 9.7 1.8 8.3 9.7 1.2 1 0 0 1 1 1 0 Draxin Apt1 PF10351.9 CDJ62523.1 - 1.5 7.5 14.7 1.5 7.6 14.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.15 CDJ62523.1 - 1.8 8.1 10.4 2.3 7.7 10.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PI3K_1B_p101 PF10486.9 CDJ62523.1 - 4.2 5.0 11.4 5.1 4.7 11.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM76 PF16046.5 CDJ62523.1 - 4.3 6.6 8.7 5.5 6.3 8.7 1.1 1 0 0 1 1 1 0 FAM76 protein Peptidase_S64 PF08192.11 CDJ62523.1 - 4.8 5.5 16.2 4.8 5.5 16.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 MPM1 PF17234.2 CDJ62523.1 - 7.9 6.7 7.9 12 6.1 7.9 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 RskA PF10099.9 CDJ62524.1 - 0.075 13.3 31.1 0.087 13.1 31.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA EphA2_TM PF14575.6 CDJ62524.1 - 0.11 13.4 0.8 0.13 13.2 0.8 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FHIPEP PF00771.20 CDJ62524.1 - 0.27 9.7 7.5 0.26 9.7 7.5 1.0 1 0 0 1 1 1 0 FHIPEP family Spt20 PF12090.8 CDJ62524.1 - 0.71 9.4 25.1 0.68 9.5 25.1 1.0 1 0 0 1 1 1 0 Spt20 family DUF4179 PF13786.6 CDJ62524.1 - 0.86 10.1 4.9 1.1 9.8 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF1840 PF08895.11 CDJ62524.1 - 0.87 10.0 12.3 1 9.7 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF533 PF04391.12 CDJ62524.1 - 0.89 9.1 20.7 0.98 9.0 20.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF533) FYDLN_acid PF09538.10 CDJ62524.1 - 0.97 10.1 7.1 1.2 9.8 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Coilin_N PF15862.5 CDJ62524.1 - 1 9.2 10.7 1.1 9.1 10.7 1.0 1 0 0 1 1 1 0 Coilin N-terminus TFIIA PF03153.13 CDJ62524.1 - 1.7 8.5 28.3 1.8 8.5 28.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 CDJ62524.1 - 1.9 7.2 9.7 2.1 7.0 9.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 IHABP4_N PF16174.5 CDJ62524.1 - 2.4 8.8 17.6 2.6 8.6 17.6 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Presenilin PF01080.17 CDJ62524.1 - 2.5 6.8 9.2 2.3 6.9 9.2 1.0 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CDJ62524.1 - 3 7.8 13.7 2.9 7.8 13.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Dehydrin PF00257.19 CDJ62524.1 - 3.4 8.2 10.7 3.6 8.1 10.7 1.1 1 0 0 1 1 1 0 Dehydrin CPSF100_C PF13299.6 CDJ62524.1 - 3.8 7.7 9.6 3.7 7.7 9.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2722 PF10846.8 CDJ62524.1 - 4.1 6.2 23.2 4.1 6.2 23.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) R_equi_Vir PF05526.11 CDJ62524.1 - 4.1 7.2 13.0 4.6 7.1 13.0 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF3450 PF11932.8 CDJ62524.1 - 4.2 6.6 22.7 4.6 6.5 22.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pex14_N PF04695.13 CDJ62524.1 - 4.2 8.0 19.4 4.5 7.9 19.4 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 CDJ62524.1 - 5.3 8.1 10.3 5.6 8.0 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3464 PF11947.8 CDJ62524.1 - 6 6.6 9.0 6.2 6.6 9.0 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 eIF3_subunit PF08597.10 CDJ62524.1 - 6.7 6.6 16.5 6.8 6.5 16.5 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit BAF1_ABF1 PF04684.13 CDJ62524.1 - 6.9 5.6 13.2 6.7 5.6 13.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UPF0560 PF10577.9 CDJ62524.1 - 7.5 4.9 14.8 7.1 5.0 14.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 AIF_C PF14721.6 CDJ62524.1 - 8.5 6.8 9.8 9.2 6.6 9.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SR-25 PF10500.9 CDJ62526.1 - 0.0029 17.2 12.0 0.0029 17.2 12.0 3.9 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein Collagen PF01391.18 CDJ62526.1 - 0.0046 16.7 25.7 0.0046 16.7 25.7 6.7 4 1 2 6 6 6 3 Collagen triple helix repeat (20 copies) Neur_chan_memb PF02932.16 CDJ62526.1 - 0.89 9.6 7.4 9.6 6.2 0.0 3.0 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Lin-8 PF03353.15 CDJ62526.1 - 2.5 7.6 22.4 0.031 13.9 1.0 3.1 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist DUF2722 PF10846.8 CDJ62526.1 - 4.8 6.0 40.2 0.0097 14.9 5.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) BT1 PF03092.16 CDJ62527.1 - 1.1e-77 261.5 20.8 1.2e-53 182.2 7.7 2.1 2 0 0 2 2 2 2 BT1 family AMPK1_CBM PF16561.5 CDJ62528.1 - 0.047 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase TFIIA PF03153.13 CDJ62528.1 - 1.6 8.7 29.3 0.27 11.2 25.0 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3306 PF11748.8 CDJ62528.1 - 5.7 7.8 15.0 4.5 8.2 4.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) zf-CCCH PF00642.24 CDJ62529.1 - 5.5e-08 32.5 17.3 4.9e-06 26.3 0.7 4.2 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ62529.1 - 1.3e-05 25.1 18.7 0.025 14.6 0.5 3.8 4 0 0 4 4 4 3 Zinc finger domain Torus PF16131.5 CDJ62529.1 - 2.1e-05 25.2 7.6 0.033 14.9 0.0 3.6 3 1 0 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 CDJ62529.1 - 0.016 15.0 14.2 0.054 13.3 0.9 3.8 4 0 0 4 4 4 0 CCCH-type zinc finger Peptidase_S51 PF03575.17 CDJ62529.1 - 0.044 13.4 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 zf-CCCH_3 PF15663.5 CDJ62529.1 - 0.26 11.5 8.3 0.089 13.0 3.7 2.3 2 0 0 2 2 2 0 Zinc-finger containing family TERB2 PF15101.6 CDJ62530.1 - 0.019 15.0 0.6 0.042 13.9 0.6 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SUIM_assoc PF16619.5 CDJ62530.1 - 0.13 12.4 3.1 2.2 8.4 0.9 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 CDJ62531.1 - 6.1e-19 67.6 0.0 1.9e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SesA PF17107.5 CDJ62532.1 - 0.022 14.9 4.2 0.59 10.3 0.3 2.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PRANC PF09372.10 CDJ62532.1 - 0.046 14.0 1.9 1.7 9.1 0.3 2.8 2 0 0 2 2 2 0 PRANC domain ApoO PF09769.9 CDJ62532.1 - 0.51 10.3 2.3 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 Apolipoprotein O MnmE_helical PF12631.7 CDJ62532.1 - 1.1 9.4 10.5 1.3 9.2 0.2 2.8 2 2 0 2 2 2 0 MnmE helical domain Chorein_N PF12624.7 CDJ62535.1 - 0.063 13.4 0.0 0.063 13.4 0.0 2.7 4 0 0 4 4 4 0 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 CDJ62535.1 - 1 9.7 5.9 1.3 9.5 0.0 4.3 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain Nucleoporin_FG PF13634.6 CDJ62536.1 - 2.3e-05 25.1 57.2 0.0006 20.6 27.8 6.7 1 1 3 4 4 4 2 Nucleoporin FG repeat region Inhibitor_I42 PF09394.10 CDJ62537.1 - 0.0038 17.6 0.0 0.012 16.0 0.0 1.8 1 1 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Inhibitor_I71 PF12628.7 CDJ62537.1 - 0.014 15.3 0.0 0.046 13.6 0.0 1.7 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor TMEM220 PF15071.6 CDJ62538.1 - 0.1 13.4 0.5 0.17 12.6 0.5 1.3 1 0 0 1 1 1 0 Transmembrane family 220, helix YL1 PF05764.13 CDJ62539.1 - 0.0014 18.8 0.7 0.0016 18.6 0.7 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Pkinase_Tyr PF07714.17 CDJ62540.1 - 1.1e-20 74.1 0.0 9.8e-09 34.9 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 CDJ62540.1 - 1.3e-13 51.0 0.0 7.1e-06 25.6 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain MORN PF02493.20 CDJ62540.1 - 0.092 12.7 0.2 1 9.4 0.0 2.7 2 0 0 2 2 2 0 MORN repeat SAM_2 PF07647.17 CDJ62540.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) FliD_N PF02465.18 CDJ62540.1 - 7.1 7.4 6.4 17 6.2 6.4 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus CRT-like PF08627.10 CDJ62541.1 - 8.5e-110 366.8 10.8 1e-109 366.6 10.8 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 CDJ62541.1 - 0.0017 17.9 1.6 0.0017 17.9 1.6 1.8 2 0 0 2 2 2 1 Solute carrier family 35 EamA PF00892.20 CDJ62541.1 - 0.0036 17.5 5.4 0.0036 17.5 5.4 3.7 3 1 0 3 3 3 1 EamA-like transporter family O-antigen_lig PF13425.6 CDJ62541.1 - 0.4 9.4 5.2 0.086 11.6 0.3 2.1 1 1 2 3 3 3 0 O-antigen ligase like membrane protein UAA PF08449.11 CDJ62541.1 - 1.1 8.4 10.2 0.1 11.8 4.2 2.0 2 0 0 2 2 2 0 UAA transporter family Methyltr_RsmB-F PF01189.17 CDJ62544.1 - 4.2e-41 140.8 0.0 6.3e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 CDJ62544.1 - 2e-07 30.9 0.0 4.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDJ62544.1 - 2.9e-05 23.9 0.0 4.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 CDJ62544.1 - 0.00013 22.1 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 CDJ62544.1 - 0.00028 21.5 0.2 0.0041 17.8 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Fibrillarin PF01269.17 CDJ62544.1 - 0.001 18.3 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin PUA PF01472.20 CDJ62544.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 PUA domain Ubie_methyltran PF01209.18 CDJ62544.1 - 0.018 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CDJ62544.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 CDJ62544.1 - 0.089 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MARVEL PF01284.23 CDJ62545.1 - 0.0087 16.1 8.4 0.0087 16.1 8.4 2.1 1 1 1 2 2 2 1 Membrane-associating domain Pkinase PF00069.25 CDJ62546.1 - 4e-12 46.1 0.0 6.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ62546.1 - 4.5e-10 39.3 0.1 1.3e-09 37.8 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ62546.1 - 8.3e-07 28.5 0.0 1.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ62547.1 - 6.7e-08 32.2 0.0 2.6e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 CDJ62547.1 - 5e-06 26.1 0.0 9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ62547.1 - 0.0043 16.4 0.0 0.0067 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mrr_cat PF04471.12 CDJ62547.1 - 0.045 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Restriction endonuclease TadE PF07811.12 CDJ62547.1 - 0.071 13.4 1.0 0.21 11.9 1.0 1.8 1 0 0 1 1 1 0 TadE-like protein Bromodomain PF00439.25 CDJ62548.1 - 4.4e-33 113.2 0.0 2e-17 63.0 0.0 2.4 2 0 0 2 2 2 2 Bromodomain Rer1 PF03248.13 CDJ62549.1 - 4e-61 205.7 1.7 4.9e-61 205.4 1.7 1.1 1 0 0 1 1 1 1 Rer1 family DUF726 PF05277.12 CDJ62551.1 - 1.1e-108 363.2 0.4 1.5e-108 362.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.22 CDJ62551.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.20 CDJ62551.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF533 PF04391.12 CDJ62552.1 - 0.0024 17.5 1.5 0.0024 17.5 1.5 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF533) tRNA-synt_2b PF00587.25 CDJ62553.1 - 1.7e-22 80.2 0.0 3.4e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 CDJ62553.1 - 6.6e-21 74.7 0.1 1.4e-20 73.6 0.1 1.6 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 CDJ62553.1 - 1.8e-19 69.7 0.0 6.8e-19 67.8 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain ProRS-C_1 PF09180.11 CDJ62553.1 - 1.3e-16 60.5 0.0 3.7e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal AP2 PF00847.20 CDJ62554.1 - 9.8e-07 28.9 0.5 0.007 16.6 0.7 2.5 2 0 0 2 2 2 2 AP2 domain zf-CCHC PF00098.23 CDJ62555.1 - 1.2e-05 25.1 3.4 1.2e-05 25.1 3.4 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ62555.1 - 0.00082 19.2 0.7 0.00082 19.2 0.7 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ62555.1 - 0.0061 16.5 0.6 0.014 15.4 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ62555.1 - 0.011 15.5 1.3 0.011 15.5 1.3 1.7 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 CDJ62556.1 - 4.2e-25 87.7 0.3 6.8e-25 87.0 0.3 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ62556.1 - 4.6e-23 81.5 0.2 7.9e-23 80.8 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ62556.1 - 8.5e-18 64.7 0.0 2.3e-17 63.3 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ62557.1 - 6.8e-13 48.9 0.0 1.3e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ62557.1 - 2.9e-10 39.9 0.0 5.6e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 CDJ62559.1 - 1.3e-25 89.3 0.1 2.7e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ62559.1 - 4e-25 88.1 0.1 9.3e-25 86.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ62559.1 - 5.7e-12 45.9 0.2 2.3e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_3 PF13456.6 CDJ62559.1 - 0.022 14.5 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like MMM1 PF10296.9 CDJ62561.1 - 0.087 11.9 0.2 0.16 11.0 0.2 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DUF4279 PF14106.6 CDJ62561.1 - 0.13 12.5 0.3 0.54 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) Hemerythrin PF01814.23 CDJ62561.1 - 0.18 12.4 1.1 0.69 10.5 0.2 2.4 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain SQS_PSY PF00494.19 CDJ62563.1 - 0.0031 17.0 0.1 0.0061 16.1 0.1 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase RYDR_ITPR PF01365.21 CDJ62564.1 - 0.18 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 RIH domain WD40 PF00400.32 CDJ62565.1 - 5.2e-14 52.4 0.0 0.00081 20.2 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat SR-25 PF10500.9 CDJ62565.1 - 2.3 7.8 14.8 0.81 9.3 1.0 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RIC3 PF15361.6 CDJ62565.1 - 5.2 7.5 5.4 1 9.7 1.4 1.9 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Pex14_N PF04695.13 CDJ62565.1 - 5.9 7.5 21.3 0.053 14.2 7.5 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDH1_2_SANT_HL1 PF18375.1 CDJ62566.1 - 0.084 13.6 4.2 0.16 12.7 0.9 2.9 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 DUF4175 PF13779.6 CDJ62566.1 - 0.72 7.7 31.0 0.94 7.3 31.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SR-25 PF10500.9 CDJ62566.1 - 1.2 8.8 51.7 0.059 13.0 24.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PA26 PF04636.13 CDJ62566.1 - 6.5 5.6 10.1 9.3 5.0 10.1 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RVP_2 PF08284.11 CDJ62567.1 - 3.1e-08 33.5 0.0 6.8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ62567.1 - 3.2e-08 34.1 0.0 7.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ62567.1 - 4.2e-08 33.6 0.0 1.1e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ62567.1 - 0.0062 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ62567.1 - 0.021 15.1 0.0 0.051 13.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Surface_antigen PF11054.8 CDJ62568.1 - 9.2e-70 235.1 8.0 1.1e-69 234.8 8.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Chromo PF00385.24 CDJ62569.1 - 2.5e-07 30.5 0.0 3.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Surface_antigen PF11054.8 CDJ62570.1 - 1.1e-70 238.1 4.8 1.2e-70 237.9 4.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62571.1 - 7e-71 238.7 6.8 8.5e-71 238.5 6.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62572.1 - 7e-64 215.8 1.7 8.5e-64 215.5 1.7 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62573.1 - 8.2e-72 241.8 4.9 1.1e-71 241.4 4.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62574.1 - 1.1e-11 44.9 0.1 1.1e-11 44.9 0.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62575.1 - 1.6e-74 250.7 6.4 1.8e-74 250.5 6.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62576.1 - 4.3e-73 246.0 5.6 5.3e-73 245.7 5.6 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Peptidase_C9 PF01707.16 CDJ62576.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C9 Surface_antigen PF11054.8 CDJ62577.1 - 4.4e-76 255.8 5.9 5.8e-76 255.4 5.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62578.1 - 9.6e-76 254.7 3.3 1.2e-75 254.4 3.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62579.1 - 9.6e-72 241.6 1.0 1.1e-71 241.4 1.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62580.1 - 6.8e-71 238.8 1.9 7.7e-71 238.6 1.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen SdpA PF17418.2 CDJ62580.1 - 0.15 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Sporulation delaying protein SdpA Surface_antigen PF11054.8 CDJ62581.1 - 2.2e-77 260.0 3.7 2.6e-77 259.8 3.7 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62583.1 - 7.3e-73 245.2 3.7 1e-72 244.8 3.7 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen zinc_ribbon_10 PF10058.9 CDJ62583.1 - 0.17 11.7 0.0 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Surface_antigen PF11054.8 CDJ62584.1 - 1.9e-73 247.1 6.3 3.9e-73 246.1 6.3 1.4 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen zinc_ribbon_10 PF10058.9 CDJ62584.1 - 0.049 13.4 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Surface_antigen PF11054.8 CDJ62585.1 - 3e-73 246.5 4.1 4.2e-73 246.0 4.1 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62586.1 - 1.5e-75 254.0 2.3 1.8e-75 253.8 2.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen zinc_ribbon_10 PF10058.9 CDJ62586.1 - 0.099 12.4 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Surface_antigen PF11054.8 CDJ62587.1 - 1e-76 257.9 5.1 1.3e-76 257.5 5.1 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen SpoIIP PF07454.11 CDJ62588.1 - 0.88 9.0 24.6 0.86 9.0 12.7 3.1 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) OATP PF03137.20 CDJ62588.1 - 2.2 6.5 6.7 4.5 5.4 6.7 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Trypan_PARP PF05887.11 CDJ62589.1 - 0.0073 16.3 4.6 0.0083 16.1 4.6 1.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.13 CDJ62589.1 - 0.95 7.9 5.5 0.91 7.9 5.5 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein RskA PF10099.9 CDJ62590.1 - 0.0003 21.1 1.3 0.0003 21.1 1.3 6.2 2 2 2 5 5 5 1 Anti-sigma-K factor rskA Neur_chan_memb PF02932.16 CDJ62590.1 - 0.055 13.5 4.6 0.39 10.7 2.9 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Kinetochor_Ybp2 PF08568.10 CDJ62590.1 - 0.38 9.2 3.4 0.59 8.5 3.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin TFIIA PF03153.13 CDJ62590.1 - 0.73 9.8 48.7 0.26 11.3 30.4 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ62590.1 - 2.1 6.5 21.1 1.4 7.0 16.2 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ62590.1 - 3.4 7.2 21.3 0.2 11.3 7.3 2.6 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein AP3D1 PF06375.11 CDJ62590.1 - 5 7.4 12.3 2.6 8.3 8.6 2.0 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 PP2C PF00481.21 CDJ62591.1 - 8.2e-16 58.4 11.7 3.3e-06 26.9 0.0 4.8 4 0 0 4 4 4 3 Protein phosphatase 2C Pkinase PF00069.25 CDJ62592.1 - 6.8e-68 228.9 0.0 1.6e-67 227.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ62592.1 - 1.9e-31 109.3 0.0 2.5e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ62592.1 - 0.00028 19.9 0.0 0.0027 16.7 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDJ62592.1 - 0.0029 16.9 0.0 0.0065 15.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDJ62592.1 - 0.0083 16.1 0.1 0.018 14.9 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ62592.1 - 0.0093 15.3 0.1 0.023 14.0 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CDJ62592.1 - 0.023 14.2 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SID-1_RNA_chan PF13965.6 CDJ62593.1 - 0.00046 18.7 0.0 0.00046 18.7 0.0 3.6 4 1 0 4 4 4 1 dsRNA-gated channel SID-1 Porin_3 PF01459.22 CDJ62594.1 - 6.4e-18 65.2 0.1 7.9e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin SR-25 PF10500.9 CDJ62595.1 - 0.016 14.8 8.6 0.016 14.8 8.6 6.2 5 2 1 6 6 6 0 Nuclear RNA-splicing-associated protein PixA PF12306.8 CDJ62596.1 - 0.0059 16.8 2.0 0.0059 16.8 2.0 1.7 1 1 1 2 2 2 1 Inclusion body protein MSA_2 PF00985.17 CDJ62596.1 - 0.14 12.5 27.6 0.27 11.6 27.6 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Vac7 PF12751.7 CDJ62596.1 - 0.16 11.4 22.4 0.036 13.5 19.4 1.3 1 1 0 1 1 1 0 Vacuolar segregation subunit 7 CCSAP PF15748.5 CDJ62596.1 - 1.1 9.4 44.7 0.022 15.0 35.3 1.9 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF4192 PF13830.6 CDJ62596.1 - 2.9 7.9 5.9 3.5 7.6 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) GREB1 PF15782.5 CDJ62596.1 - 3.5 4.6 29.6 3.6 4.6 29.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Dicty_REP PF05086.12 CDJ62596.1 - 7.2 4.5 18.1 8.4 4.2 18.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RSRP PF17069.5 CDJ62596.1 - 10 5.6 28.1 17 4.9 28.1 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Activator_LAG-3 PF11498.8 CDJ62597.1 - 7.2e-07 28.5 41.2 7.2e-07 28.5 41.2 9.8 7 2 2 9 9 9 1 Transcriptional activator LAG-3 Pkinase PF00069.25 CDJ62597.1 - 3.3e-05 23.4 0.1 3.3e-05 23.4 0.1 5.3 4 2 1 5 5 5 1 Protein kinase domain SR-25 PF10500.9 CDJ62597.1 - 0.00035 20.3 19.9 0.00035 20.3 19.9 11.4 8 3 3 11 11 11 3 Nuclear RNA-splicing-associated protein Utp14 PF04615.13 CDJ62597.1 - 0.00062 18.5 18.5 0.00062 18.5 18.5 5.5 2 2 3 5 5 5 1 Utp14 protein PAP1 PF08601.10 CDJ62597.1 - 0.00093 19.0 6.1 0.00093 19.0 6.1 9.4 4 2 3 8 8 8 2 Transcription factor PAP1 RskA PF10099.9 CDJ62598.1 - 0.05 13.9 19.4 0.077 13.3 19.4 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF1644 PF07800.12 CDJ62598.1 - 0.2 11.7 5.2 0.044 13.8 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) RAP1 PF07218.11 CDJ62598.1 - 0.55 8.5 4.4 0.6 8.3 4.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TFIIA PF03153.13 CDJ62598.1 - 0.63 10.0 25.6 0.69 9.9 25.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit R_equi_Vir PF05526.11 CDJ62598.1 - 2.4 8.0 9.3 1.3 8.8 7.4 1.6 1 1 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF4834 PF16118.5 CDJ62598.1 - 2.7 9.0 7.2 0.8 10.7 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SUIM_assoc PF16619.5 CDJ62599.1 - 0.017 15.2 15.0 1.4 9.1 15.0 2.7 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ62599.1 - 0.091 12.7 13.1 0.093 12.7 13.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPDFL PF15060.6 CDJ62599.1 - 4.1 8.0 6.1 6.9 7.2 5.6 1.7 1 1 0 1 1 1 0 Differentiation and proliferation regulator Androgen_recep PF02166.16 CDJ62599.1 - 5.1 5.8 15.5 6.2 5.6 15.3 1.3 1 1 0 1 1 1 0 Androgen receptor Chorion_2 PF03964.15 CDJ62600.1 - 0.0072 17.1 5.1 0.0098 16.7 5.1 1.5 1 1 0 1 1 1 1 Chorion family 2 DUF5423 PF17461.2 CDJ62600.1 - 0.018 13.9 0.3 0.021 13.7 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) SR-25 PF10500.9 CDJ62600.1 - 0.047 13.3 2.8 0.057 13.0 2.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein OHA PF14418.6 CDJ62601.1 - 3.6e-13 49.1 0.0 2e-12 46.7 0.0 2.3 1 0 0 1 1 1 1 OST-HTH Associated domain OST-HTH PF12872.7 CDJ62601.1 - 0.022 14.5 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 OST-HTH/LOTUS domain AAR2 PF05282.11 CDJ62602.1 - 6.9e-58 196.7 0.1 2.2e-56 191.8 0.0 2.3 2 0 0 2 2 2 1 AAR2 protein Spt20 PF12090.8 CDJ62602.1 - 0.0018 18.0 0.2 0.0018 18.0 0.2 3.1 3 0 0 3 3 3 1 Spt20 family TFIIA PF03153.13 CDJ62602.1 - 0.0028 17.7 31.1 0.086 12.8 11.9 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF2052 PF09747.9 CDJ62602.1 - 0.15 12.2 22.3 0.14 12.3 1.7 3.3 2 1 1 3 3 3 0 Coiled-coil domain containing protein (DUF2052) RskA PF10099.9 CDJ62603.1 - 0.012 15.9 0.1 0.012 15.9 0.1 3.9 2 2 0 2 2 2 0 Anti-sigma-K factor rskA Shadoo PF14999.6 CDJ62603.1 - 0.16 12.1 0.2 0.16 12.1 0.2 4.2 2 1 2 4 4 4 0 Shadow of prion protein, neuroprotective YajC PF02699.15 CDJ62603.1 - 0.57 10.1 1.5 1.1 9.2 1.5 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Ribosomal_60s PF00428.19 CDJ62603.1 - 2.2 8.9 57.6 4 8.1 4.6 4.6 4 0 0 4 4 4 0 60s Acidic ribosomal protein RT_RNaseH_2 PF17919.1 CDJ62604.1 - 3.4e-15 55.9 0.0 5.8e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ62604.1 - 3.1e-05 24.2 0.0 8e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ62605.1 - 1e-11 45.0 0.0 1.9e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Gcd10p PF04189.13 CDJ62606.1 - 5.4e-16 58.6 0.0 8.1e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family Tfb2 PF03849.14 CDJ62607.1 - 1.2e-09 37.6 0.0 0.0084 15.1 0.0 3.0 3 0 0 3 3 3 3 Transcription factor Tfb2 Cyclin_N PF00134.23 CDJ62608.1 - 4.7e-12 45.8 0.1 5.2e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 CDJ62608.1 - 0.013 15.5 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF677 PF05055.12 CDJ62610.1 - 0.0056 15.6 0.7 0.007 15.3 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF677) CD20 PF04103.15 CDJ62610.1 - 0.013 15.6 0.8 0.023 14.8 0.8 1.5 1 1 0 1 1 1 0 CD20-like family TFIIA PF03153.13 CDJ62610.1 - 0.056 13.4 34.5 0.071 13.1 34.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.15 CDJ62610.1 - 0.072 12.0 6.9 0.089 11.7 6.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1980 PF09323.10 CDJ62610.1 - 0.097 12.6 6.7 0.13 12.2 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SID-1_RNA_chan PF13965.6 CDJ62610.1 - 0.11 10.9 4.5 0.13 10.6 4.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 O-antigen_lig PF13425.6 CDJ62610.1 - 0.37 9.5 2.1 0.42 9.3 2.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Neur_chan_memb PF02932.16 CDJ62610.1 - 0.41 10.7 5.2 0.49 10.4 5.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FHIPEP PF00771.20 CDJ62610.1 - 0.44 9.0 12.4 0.52 8.7 12.4 1.0 1 0 0 1 1 1 0 FHIPEP family DUF2232 PF09991.9 CDJ62610.1 - 0.45 9.7 9.1 0.62 9.2 9.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DDHD PF02862.17 CDJ62610.1 - 0.5 10.5 7.7 0.6 10.2 7.7 1.1 1 0 0 1 1 1 0 DDHD domain AAA_23 PF13476.6 CDJ62610.1 - 0.72 10.3 11.0 0.97 9.9 11.0 1.2 1 0 0 1 1 1 0 AAA domain Connexin PF00029.19 CDJ62610.1 - 0.74 9.5 5.9 0.96 9.2 5.9 1.2 1 0 0 1 1 1 0 Connexin DUF4045 PF13254.6 CDJ62610.1 - 0.75 9.4 10.5 1 9.0 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) EIF4E-T PF10477.9 CDJ62610.1 - 1.1 8.1 22.0 1.3 7.7 22.0 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E SLATT_1 PF18181.1 CDJ62610.1 - 1.3 8.9 20.2 0.11 12.4 15.3 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 VIT1 PF01988.19 CDJ62610.1 - 1.4 8.7 9.4 2.2 8.1 9.4 1.3 1 0 0 1 1 1 0 VIT family DUF4786 PF16027.5 CDJ62610.1 - 1.5 9.4 8.8 2 8.9 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4786) Peptidase_C37 PF05416.12 CDJ62610.1 - 2 6.8 11.6 2.5 6.5 11.6 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Ndc1_Nup PF09531.10 CDJ62610.1 - 2.1 6.9 14.4 2.4 6.8 14.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AI-2E_transport PF01594.16 CDJ62610.1 - 2.6 7.1 5.7 2.8 7.0 5.7 1.0 1 0 0 1 1 1 0 AI-2E family transporter NEMP PF10225.9 CDJ62610.1 - 2.7 7.6 7.2 3.5 7.2 7.2 1.2 1 0 0 1 1 1 0 NEMP family eIF-3_zeta PF05091.12 CDJ62610.1 - 3.7 6.4 16.4 4.6 6.1 16.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4667 PF15700.5 CDJ62610.1 - 4 7.5 12.1 5.7 7.0 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) YjbH PF06082.11 CDJ62610.1 - 4.6 5.9 16.2 5.8 5.6 16.2 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH FAM199X PF15814.5 CDJ62610.1 - 4.9 6.1 8.3 6.4 5.7 8.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X CLN3 PF02487.17 CDJ62610.1 - 5.6 5.9 8.4 7 5.6 8.4 1.2 1 0 0 1 1 1 0 CLN3 protein FAM60A PF15396.6 CDJ62610.1 - 7.3 6.5 8.6 10 6.0 8.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A FliP PF00813.20 CDJ62610.1 - 9.4 6.1 10.6 13 5.6 10.6 1.2 1 0 0 1 1 1 0 FliP family Pescadillo_N PF06732.11 CDJ62611.1 - 6.3e-09 35.8 9.2 2.6e-07 30.5 0.0 3.1 2 1 1 3 3 3 2 Pescadillo N-terminus BUD22 PF09073.10 CDJ62611.1 - 1.4e-06 27.9 43.4 4.7e-06 26.2 32.2 2.3 2 0 0 2 2 2 2 BUD22 BRCT_2 PF16589.5 CDJ62611.1 - 5.9e-05 23.4 0.2 0.00022 21.6 0.2 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain TFIIA PF03153.13 CDJ62611.1 - 0.00013 22.1 55.2 0.0021 18.1 23.8 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ62611.1 - 0.0024 17.5 27.7 0.0024 17.5 27.7 3.3 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein DUF3439 PF11921.8 CDJ62611.1 - 0.026 14.5 2.2 0.094 12.7 2.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Spt20 PF12090.8 CDJ62612.1 - 8.3e-05 22.3 18.4 9.3e-05 22.1 18.4 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ62612.1 - 0.00018 20.6 13.6 0.00021 20.4 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) CSM2 PF16834.5 CDJ62612.1 - 0.0009 18.9 1.9 0.0012 18.5 1.9 1.1 1 0 0 1 1 1 1 Shu complex component Csm2, DNA-binding SMYLE_N PF18615.1 CDJ62612.1 - 0.0021 17.7 4.1 0.0024 17.5 4.1 1.1 1 0 0 1 1 1 1 Short myomegalin-like EB1 binding proteins, N-terminal domain DDHD PF02862.17 CDJ62612.1 - 0.0032 17.7 2.6 0.0034 17.6 2.6 1.2 1 0 0 1 1 1 1 DDHD domain MecA PF05389.12 CDJ62612.1 - 0.0034 17.1 3.1 0.004 16.8 3.1 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) Med15 PF09606.10 CDJ62612.1 - 0.0037 16.0 17.5 0.004 15.9 17.5 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ62612.1 - 0.012 15.7 23.8 0.013 15.5 23.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ62612.1 - 0.022 15.7 3.9 0.03 15.3 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pannexin_like PF12534.8 CDJ62612.1 - 0.025 13.7 2.9 0.033 13.3 2.9 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 RAB3GAP2_N PF14655.6 CDJ62612.1 - 0.027 13.7 4.0 0.033 13.5 4.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SLATT_1 PF18181.1 CDJ62612.1 - 0.033 14.1 9.1 0.043 13.7 5.9 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF45 PF01863.17 CDJ62612.1 - 0.034 14.2 3.8 0.04 14.0 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 Suf PF05843.14 CDJ62612.1 - 0.034 14.1 8.0 0.038 14.0 8.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AIRC PF00731.20 CDJ62612.1 - 0.038 13.6 0.2 0.038 13.6 0.2 2.0 2 0 0 2 2 2 0 AIR carboxylase FHIPEP PF00771.20 CDJ62612.1 - 0.038 12.5 4.9 0.042 12.3 4.9 1.1 1 0 0 1 1 1 0 FHIPEP family DUF3499 PF12005.8 CDJ62612.1 - 0.047 14.3 1.0 0.047 14.3 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) MCR_alpha PF02249.17 CDJ62612.1 - 0.049 14.1 1.9 0.063 13.7 1.9 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain SpoVR PF04293.13 CDJ62612.1 - 0.067 11.9 3.4 0.069 11.8 3.4 1.1 1 0 0 1 1 1 0 SpoVR like protein Activator_LAG-3 PF11498.8 CDJ62612.1 - 0.086 11.8 24.7 0.087 11.8 24.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EPL1 PF10513.9 CDJ62612.1 - 0.086 13.2 4.2 0.1 13.0 4.2 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like MDM31_MDM32 PF08118.11 CDJ62612.1 - 0.089 11.5 3.5 0.12 11.1 3.5 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF1840 PF08895.11 CDJ62612.1 - 0.096 13.0 12.0 0.047 14.0 10.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) TERB2 PF15101.6 CDJ62612.1 - 0.13 12.3 8.3 0.14 12.2 8.3 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Mus7 PF09462.10 CDJ62612.1 - 0.19 10.6 7.7 0.2 10.5 7.7 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family EIF4E-T PF10477.9 CDJ62612.1 - 0.24 10.2 10.9 0.25 10.1 10.9 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E V_ATPase_I PF01496.19 CDJ62612.1 - 0.26 9.1 5.9 0.29 9.0 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 CDJ62612.1 - 0.32 9.8 5.7 0.35 9.7 5.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3464 PF11947.8 CDJ62612.1 - 0.36 10.6 3.7 0.53 10.0 3.7 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Presenilin PF01080.17 CDJ62612.1 - 0.46 9.2 6.4 0.49 9.1 6.4 1.1 1 0 0 1 1 1 0 Presenilin DUF5421 PF17458.2 CDJ62612.1 - 0.54 9.6 12.7 0.75 9.1 12.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) UPF0560 PF10577.9 CDJ62612.1 - 0.61 8.5 10.3 0.59 8.6 10.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PigN PF04987.14 CDJ62612.1 - 0.65 8.8 2.3 0.72 8.6 2.3 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Roughex PF06020.11 CDJ62612.1 - 1.6 7.8 9.4 1.8 7.6 9.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF5349 PF17298.2 CDJ62612.1 - 1.8 8.2 12.6 2.4 7.8 12.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) AAA_23 PF13476.6 CDJ62612.1 - 7.3 7.0 12.6 9.5 6.7 12.6 1.1 1 0 0 1 1 1 0 AAA domain DUF5323 PF17257.2 CDJ62613.1 - 0.011 15.6 0.2 0.015 15.1 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5323) Trp_oprn_chp PF09534.10 CDJ62613.1 - 0.92 9.3 31.1 1.1 9.0 31.1 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Myosin_head PF00063.21 CDJ62614.1 - 7.6e-95 318.6 28.4 1.8e-37 128.9 0.1 6.2 5 2 2 7 7 7 5 Myosin head (motor domain) IQ PF00612.27 CDJ62614.1 - 0.00018 21.0 38.0 0.016 14.9 1.0 6.3 6 0 0 6 6 6 3 IQ calmodulin-binding motif SR-25 PF10500.9 CDJ62614.1 - 0.0022 17.6 9.3 0.0022 17.6 9.3 6.1 6 0 0 6 6 6 2 Nuclear RNA-splicing-associated protein AAA_5 PF07728.14 CDJ62614.1 - 0.0032 17.5 0.1 0.0093 16.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RskA PF10099.9 CDJ62614.1 - 0.0053 17.1 13.0 0.0053 17.1 13.0 10.2 5 3 2 8 8 8 4 Anti-sigma-K factor rskA WD40 PF00400.32 CDJ62614.1 - 0.015 16.1 0.0 0.085 13.8 0.0 2.3 1 0 0 1 1 1 0 WD domain, G-beta repeat AAA PF00004.29 CDJ62614.1 - 4.2 7.8 0.0 4.2 7.8 0.0 3.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 CDJ62615.1 - 1.9e-38 131.6 0.0 3.7e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ62615.1 - 2.1e-32 111.9 1.6 1.7e-31 108.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ62615.1 - 7.3e-10 38.6 0.1 1.3e-09 37.7 0.0 1.5 2 0 0 2 2 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ62615.1 - 3.1e-06 26.7 2.0 1.3e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDJ62615.1 - 1.3e-05 24.8 0.9 4.6e-05 23.1 0.9 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ62615.1 - 0.0017 18.4 0.0 0.0059 16.7 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ62615.1 - 0.0044 16.9 5.3 0.0065 16.4 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_24 PF13479.6 CDJ62615.1 - 0.044 13.5 0.3 0.54 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Presenilin PF01080.17 CDJ62615.1 - 0.19 10.5 18.3 0.42 9.3 11.1 2.1 2 0 0 2 2 2 0 Presenilin ABC_tran PF00005.27 CDJ62615.1 - 1.8 9.1 9.3 63 4.1 9.3 2.6 1 1 0 1 1 1 0 ABC transporter Ribosomal_60s PF00428.19 CDJ62615.1 - 1.8 9.2 13.8 0.36 11.4 4.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein RBP_receptor PF14752.6 CDJ62615.1 - 1.9 7.0 4.4 3.2 6.2 4.4 1.3 1 0 0 1 1 1 0 Retinol binding protein receptor eIF-3_zeta PF05091.12 CDJ62615.1 - 2 7.3 12.1 3.7 6.4 12.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MID_MedPIWI PF18296.1 CDJ62615.1 - 2.6 7.8 16.4 0.12 12.2 2.5 2.2 2 0 0 2 2 2 0 MID domain of medPIWI SpoIIP PF07454.11 CDJ62615.1 - 8.3 5.8 13.0 5.5 6.4 6.2 2.8 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) SR-25 PF10500.9 CDJ62616.1 - 0.00049 19.8 18.7 0.00049 19.8 18.7 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4366 PF14283.6 CDJ62616.1 - 0.026 14.6 0.9 0.026 14.6 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) DUF3112 PF11309.8 CDJ62616.1 - 0.068 12.6 2.9 0.12 11.8 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) SfLAP PF11139.8 CDJ62616.1 - 0.51 9.7 5.9 0.15 11.5 2.7 1.7 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein HCO3_cotransp PF00955.21 CDJ62616.1 - 3 6.6 5.1 4.1 6.1 5.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF737 PF05300.11 CDJ62616.1 - 3.9 7.8 23.5 0.037 14.4 12.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DUF1345 PF07077.11 CDJ62616.1 - 9.2 5.9 10.6 2.8 7.6 0.9 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1345) Syja_N PF02383.18 CDJ62617.1 - 1.2e-33 116.9 0.0 3.8e-16 59.3 0.0 4.5 3 2 1 4 4 4 2 SacI homology domain AMP-binding PF00501.28 CDJ62618.1 - 3.2e-79 266.5 0.0 4.6e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF2722 PF10846.8 CDJ62619.1 - 0.004 16.2 4.6 0.004 16.2 4.6 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) MCR_alpha PF02249.17 CDJ62619.1 - 0.058 13.8 0.4 0.058 13.8 0.4 3.1 3 0 0 3 3 3 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain LPD23 PF18838.1 CDJ62620.1 - 0.023 14.5 2.1 5.8 6.8 0.7 3.2 2 0 0 2 2 2 0 Large polyvalent protein associated domain 23 VTC PF09359.10 CDJ62624.1 - 3.9e-13 49.4 0.0 7.3e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 VTC domain DUF202 PF02656.15 CDJ62624.1 - 4.6e-13 49.4 5.6 4.6e-13 49.4 5.6 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF202) SPX PF03105.19 CDJ62624.1 - 1.2e-05 25.4 7.6 2.4e-05 24.4 1.6 6.2 4 1 2 6 6 6 4 SPX domain DUF21 PF01595.20 CDJ62625.1 - 2.7e-27 95.6 5.0 2.7e-27 95.6 5.0 2.2 3 0 0 3 3 3 1 Cyclin M transmembrane N-terminal domain DUF1645 PF07816.11 CDJ62625.1 - 0.0013 19.4 5.9 0.0013 19.4 5.9 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1645) YrhC PF14143.6 CDJ62625.1 - 0.11 12.6 2.1 0.35 11.0 2.1 1.8 1 0 0 1 1 1 0 YrhC-like protein Adipogenin PF15202.6 CDJ62625.1 - 0.48 10.5 1.5 0.68 10.0 0.0 2.0 2 0 0 2 2 2 0 Adipogenin DUF4667 PF15700.5 CDJ62625.1 - 5.9 6.9 19.3 0.33 11.0 11.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ62626.1 - 0.053 13.5 37.3 0.074 13.0 37.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CDJ62626.1 - 0.87 6.6 17.9 1.1 6.3 17.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2052 PF09747.9 CDJ62626.1 - 9.6 6.3 14.6 5 7.2 12.2 1.7 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Peptidase_S64 PF08192.11 CDJ62627.1 - 3.4 6.1 14.0 5.1 5.5 14.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.13 CDJ62627.1 - 4.8 7.1 30.4 0.39 10.7 21.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 CDJ62628.1 - 4e-10 39.5 5.3 7.8e-05 22.2 0.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase RskA PF10099.9 CDJ62628.1 - 4.8e-08 33.5 3.8 0.001 19.4 6.7 2.4 2 1 0 2 2 2 2 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ62628.1 - 0.0015 17.9 8.4 0.07 12.3 1.3 2.3 2 0 0 2 2 2 2 Sin-like protein conserved region DUF4667 PF15700.5 CDJ62628.1 - 0.0021 18.2 3.2 0.0021 18.2 3.2 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4667) KR PF08659.10 CDJ62628.1 - 0.0023 17.9 0.0 0.0023 17.9 0.0 2.3 3 0 0 3 3 3 1 KR domain DUF1645 PF07816.11 CDJ62628.1 - 0.015 15.9 1.4 0.015 15.9 1.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) Med15 PF09606.10 CDJ62628.1 - 0.015 14.1 26.0 0.12 11.1 4.3 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Polysacc_synt_2 PF02719.15 CDJ62628.1 - 0.016 14.3 0.4 0.042 13.0 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF2126 PF09899.9 CDJ62628.1 - 0.048 11.7 0.2 0.07 11.2 0.2 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) ORC_WH_C PF18137.1 CDJ62628.1 - 0.054 13.6 5.6 0.46 10.6 0.8 2.3 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF3391 PF11871.8 CDJ62628.1 - 0.071 13.6 4.4 1.6 9.3 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF2722 PF10846.8 CDJ62628.1 - 0.21 10.5 27.1 0.068 12.1 6.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF533 PF04391.12 CDJ62628.1 - 0.3 10.6 16.1 1.3 8.5 10.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF533) EIIBC-GUT_N PF03612.14 CDJ62628.1 - 0.44 10.3 4.8 15 5.3 0.1 2.9 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus Sporozoite_P67 PF05642.11 CDJ62628.1 - 1.9 6.5 11.6 0.029 12.5 1.8 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Ribosomal_60s PF00428.19 CDJ62628.1 - 1.9 9.2 11.6 1.3 9.7 6.9 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein OmpH PF03938.14 CDJ62628.1 - 2.9 8.2 24.0 1.5 9.2 4.6 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) IHABP4_N PF16174.5 CDJ62628.1 - 3.5 8.2 16.0 2.6 8.6 6.8 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Zn_peptidase PF04228.13 CDJ62628.1 - 6.5 6.1 13.4 0.92 8.9 5.4 2.1 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase SbcCD_C PF13558.6 CDJ62629.1 - 0.26 11.6 0.3 0.26 11.6 0.3 2.0 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit ACC_epsilon PF13822.6 CDJ62629.1 - 0.43 11.3 6.5 5 7.9 0.7 2.3 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit DUF2076 PF09849.9 CDJ62629.1 - 1.1 9.3 26.2 1.3 9.0 26.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Hydin_ADK PF17213.3 CDJ62629.1 - 5.7 7.2 10.9 7.1 6.8 10.9 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PAF PF15715.5 CDJ62630.1 - 0.0013 19.4 7.3 0.0013 19.4 7.3 1.9 2 0 0 2 2 2 1 PCNA-associated factor histone like domain DUF3446 PF11928.8 CDJ62630.1 - 0.058 13.7 12.8 0.046 14.0 9.1 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain RNA_pol_3_Rpc31 PF11705.8 CDJ62630.1 - 0.06 13.6 15.1 0.14 12.4 15.1 1.6 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 CDJ62630.1 - 0.42 10.0 23.6 0.74 9.2 23.6 1.4 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.11 CDJ62630.1 - 0.61 10.1 26.3 0.97 9.4 26.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) BAF1_ABF1 PF04684.13 CDJ62630.1 - 1.3 8.0 17.2 0.044 12.9 10.8 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.22 CDJ62630.1 - 2.9 7.0 7.0 6.8 5.8 7.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 CDJ62630.1 - 4.1 5.5 25.0 6.5 4.8 25.0 1.3 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 CDJ62630.1 - 4.2 6.7 15.3 6.6 6.1 15.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Lin-8 PF03353.15 CDJ62630.1 - 9.7 5.6 19.5 23 4.4 0.0 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SUIM_assoc PF16619.5 CDJ62634.1 - 0.013 15.5 21.9 0.28 11.3 9.1 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4407 PF14362.6 CDJ62634.1 - 2.4 7.4 12.3 4.7 6.5 12.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Suf PF05843.14 CDJ62634.1 - 6.2 6.7 6.9 14 5.5 4.3 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4667 PF15700.5 CDJ62635.1 - 0.0081 16.3 1.3 0.015 15.4 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) CD34_antigen PF06365.12 CDJ62635.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Spt20 PF12090.8 CDJ62635.1 - 0.039 13.6 0.9 0.053 13.1 0.9 1.1 1 0 0 1 1 1 0 Spt20 family SPX PF03105.19 CDJ62635.1 - 0.043 13.7 1.0 0.059 13.3 1.0 1.2 1 0 0 1 1 1 0 SPX domain Sporozoite_P67 PF05642.11 CDJ62635.1 - 0.057 11.5 0.6 0.13 10.4 0.6 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NapE PF06796.11 CDJ62635.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE DUF515 PF04415.12 CDJ62635.1 - 1 7.6 2.2 1.5 7.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TBP PF00352.21 CDJ62636.1 - 2.9e-32 110.4 0.2 2.6e-15 56.1 0.0 3.3 2 1 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CDJ62636.1 - 0.00055 20.0 0.1 1 9.5 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) TFIIA PF03153.13 CDJ62636.1 - 8.5 6.3 16.2 6.1 6.7 2.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LapA_dom PF06305.11 CDJ62637.1 - 0.0041 16.9 0.5 0.0041 16.9 0.5 6.2 5 1 0 5 5 5 1 Lipopolysaccharide assembly protein A domain SARAF PF06682.12 CDJ62637.1 - 9.9 5.7 0.0 9.9 5.7 0.0 3.3 2 2 1 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis TBPIP PF07106.13 CDJ62638.1 - 3.1e-15 55.9 0.1 7.1e-15 54.7 0.0 1.6 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 CDJ62638.1 - 0.02 15.0 0.0 0.055 13.6 0.0 1.9 1 0 0 1 1 1 0 Leucine zipper with capping helix domain TF_AP-2 PF03299.14 CDJ62638.1 - 0.075 13.0 2.3 0.12 12.4 2.3 1.2 1 0 0 1 1 1 0 Transcription factor AP-2 FANCAA PF15146.6 CDJ62638.1 - 0.25 10.4 8.8 0.032 13.3 4.8 1.5 2 0 0 2 2 2 0 Fanconi anemia-associated YebO PF13974.6 CDJ62638.1 - 9.5 6.4 20.2 5.6 7.1 5.1 3.4 3 0 0 3 3 3 0 YebO-like protein Etmic-2 PF06670.11 CDJ62641.1 - 3.5e-186 618.7 30.5 1.5e-184 613.4 30.5 2.0 1 1 0 1 1 1 1 Microneme protein Etmic-2 PrkA PF06798.12 CDJ62642.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain Pkinase_Tyr PF07714.17 CDJ62643.1 - 0.0003 20.2 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ62643.1 - 0.016 14.6 0.0 0.046 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain SNF2_N PF00176.23 CDJ62644.1 - 1.3e-67 228.0 0.0 2e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_5 PF14634.6 CDJ62644.1 - 1.3e-07 31.4 5.1 3.3e-07 30.1 5.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDJ62644.1 - 4.6e-07 29.6 5.3 8.9e-07 28.7 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ62644.1 - 3.9e-05 23.4 6.5 9e-05 22.3 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ62644.1 - 0.00022 21.0 7.2 0.00092 19.0 7.4 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CDJ62644.1 - 0.0023 17.7 8.5 0.0068 16.2 8.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ62644.1 - 0.003 17.9 8.0 0.0076 16.6 8.0 1.8 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.31 CDJ62644.1 - 0.0041 17.4 0.0 0.2 12.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.6 CDJ62644.1 - 0.016 15.3 8.2 0.04 14.1 8.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CDJ62644.1 - 0.019 15.0 6.4 0.05 13.6 6.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 CDJ62644.1 - 0.049 13.5 2.0 0.13 12.2 2.0 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.20 CDJ62644.1 - 0.61 9.9 7.4 11 5.8 7.9 2.4 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger FYDLN_acid PF09538.10 CDJ62644.1 - 2.7 8.7 8.6 0.38 11.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C3HC4_5 PF17121.5 CDJ62644.1 - 7.7 6.5 7.6 21 5.1 6.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_C48 PF02902.19 CDJ62646.1 - 8.9e-11 42.0 3.5 5.4e-10 39.5 3.5 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Kinesin PF00225.23 CDJ62648.1 - 4.4e-10 39.0 0.0 5.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Ank_2 PF12796.7 CDJ62650.1 - 1.1e-05 25.9 0.1 1.3e-05 25.7 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ62650.1 - 0.0018 18.8 0.0 0.0027 18.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ62650.1 - 0.0038 17.6 0.0 0.31 11.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 CDJ62650.1 - 0.0063 16.9 0.0 4.5 7.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CDJ62650.1 - 0.023 15.0 0.1 0.065 13.6 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Peptidase_M24 PF00557.24 CDJ62652.1 - 1.3e-56 191.6 0.0 2.3e-56 190.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CDJ62652.1 - 2.7e-13 49.7 0.0 6.1e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain FBPase PF00316.20 CDJ62653.1 - 3.8e-32 111.3 0.0 6.1e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain SF-assemblin PF06705.11 CDJ62655.1 - 3e-32 111.9 16.5 4.2e-32 111.5 16.5 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin Ribosomal_L17 PF01196.19 CDJ62655.1 - 2.4e-07 31.5 1.5 2.1e-06 28.5 0.0 2.7 2 1 0 2 2 2 1 Ribosomal protein L17 Baculo_PEP_C PF04513.12 CDJ62655.1 - 0.023 14.7 9.2 0.25 11.4 0.4 3.5 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Csm1_B PF18211.1 CDJ62655.1 - 0.08 12.8 0.9 0.26 11.1 0.1 2.3 2 0 0 2 2 2 0 Csm1 subunit domain B Rab_bind PF16704.5 CDJ62655.1 - 0.33 11.0 3.7 1.1 9.3 1.5 3.0 1 1 2 3 3 3 0 Rab binding domain Spore_II_R PF09551.10 CDJ62655.1 - 4.2 7.8 5.7 3.3 8.2 0.6 2.5 2 1 1 3 3 3 0 Stage II sporulation protein R (spore_II_R) betaPIX_CC PF16523.5 CDJ62655.1 - 9.9 6.1 12.7 2 8.3 0.3 3.0 3 0 0 3 3 3 0 betaPIX coiled coil Peptidase_C50 PF03568.17 CDJ62656.1 - 6.5e-06 25.5 0.0 8.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C50 DAN PF03045.15 CDJ62657.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 DAN domain Peptidase_S8 PF00082.22 CDJ62660.1 - 2.3e-43 148.6 0.1 3.9e-43 147.8 0.1 1.2 1 0 0 1 1 1 1 Subtilase family EGF_3 PF12947.7 CDJ62660.1 - 9.6e-15 54.5 39.0 7.6e-05 22.8 10.6 4.4 4 0 0 4 4 4 4 EGF domain EGF_CA PF07645.15 CDJ62660.1 - 2.4e-14 53.2 42.6 4.4e-09 36.4 6.4 4.6 4 1 1 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.7 CDJ62660.1 - 3.4e-10 39.6 14.0 4.4e-05 23.3 1.6 3.5 3 0 0 3 3 3 2 Complement Clr-like EGF-like S_locus_glycop PF00954.20 CDJ62660.1 - 0.012 16.1 28.4 0.091 13.3 2.6 3.7 3 0 0 3 3 3 0 S-locus glycoprotein domain Cu-binding_MopE PF11617.8 CDJ62660.1 - 0.092 12.9 2.7 0.28 11.4 2.7 1.9 1 0 0 1 1 1 0 Putative metal-binding motif Plasmod_Pvs28 PF06247.11 CDJ62660.1 - 0.11 12.9 33.0 0.07 13.4 7.3 5.1 4 1 1 5 5 5 0 Pvs28 EGF domain EGF PF00008.27 CDJ62660.1 - 0.18 12.1 39.1 0.12 12.7 3.0 4.6 4 0 0 4 4 4 0 EGF-like domain EGF_MSP1_1 PF12946.7 CDJ62660.1 - 0.28 11.2 40.5 0.037 14.1 5.1 4.5 4 0 0 4 4 4 0 MSP1 EGF domain 1 hEGF PF12661.7 CDJ62660.1 - 2.7 8.8 35.5 0.26 12.0 3.8 5.0 4 1 0 4 4 4 0 Human growth factor-like EGF FXa_inhibition PF14670.6 CDJ62660.1 - 3.5 8.0 41.3 0.34 11.2 3.3 4.5 4 0 0 4 4 4 0 Coagulation Factor Xa inhibitory site V-SNARE_C PF12352.8 CDJ62661.1 - 2e-13 50.4 0.1 4.3e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CDJ62661.1 - 0.0043 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Sec20 Rx_N PF18052.1 CDJ62661.1 - 0.12 12.7 2.4 0.23 11.8 1.9 1.7 1 1 0 1 1 1 0 Rx N-terminal domain PhaC_N PF07167.13 CDJ62661.1 - 0.17 11.5 0.1 0.25 11.0 0.1 1.2 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus RRM_1 PF00076.22 CDJ62662.1 - 5.6e-06 26.1 0.1 1.9e-05 24.4 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ_C PF01556.18 CDJ62663.1 - 6.9e-34 117.1 0.1 9.7e-34 116.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ62663.1 - 5.2e-23 80.9 1.9 9.1e-23 80.2 1.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDJ62663.1 - 7e-13 48.7 16.3 7e-13 48.7 16.3 2.3 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 CDJ62663.1 - 0.14 12.1 10.0 3 7.9 0.8 2.9 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Tnp_zf-ribbon_2 PF13842.6 CDJ62663.1 - 0.18 12.6 10.5 1.1 10.1 0.1 3.5 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon HypA PF01155.19 CDJ62663.1 - 0.46 10.5 10.8 1.7 8.7 0.5 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 CDJ62663.1 - 6 7.1 9.9 5.7 7.2 1.8 3.3 2 1 1 3 3 3 0 zinc RING finger of MSL2 HEAT PF02985.22 CDJ62664.1 - 8.2e-08 31.9 12.9 0.0088 16.2 0.2 7.1 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 CDJ62664.1 - 2.5e-05 24.6 11.5 0.054 13.9 0.0 6.1 5 2 2 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 CDJ62664.1 - 0.1 13.2 7.6 13 6.4 1.1 4.5 3 2 0 3 3 3 0 HEAT-like repeat Otopetrin PF03189.13 CDJ62665.1 - 0.038 12.8 0.0 5 5.8 0.0 4.0 3 2 0 3 3 3 0 Otopetrin Mlh1_C PF16413.5 CDJ62666.1 - 4e-54 183.8 1.9 4e-54 183.8 1.9 4.1 3 1 0 3 3 3 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CDJ62666.1 - 1.6e-25 89.0 0.0 3.6e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CDJ62666.1 - 2.9e-08 33.6 0.0 1.1e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ62666.1 - 0.00045 20.7 0.0 0.0014 19.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cmc1 PF08583.10 CDJ62667.1 - 0.0064 16.5 1.3 0.012 15.7 1.3 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like FAP206 PF12018.8 CDJ62668.1 - 1.4e-10 41.2 0.7 1.4e-10 41.2 0.7 2.1 2 1 0 2 2 2 1 Domain of unknown function PhoD PF09423.10 CDJ62669.1 - 1.5e-05 24.2 1.8 1.5e-05 24.2 1.8 4.1 1 1 2 3 3 2 1 PhoD-like phosphatase GAGA_bind PF06217.12 CDJ62669.1 - 0.00033 21.0 12.9 0.00054 20.4 12.9 1.3 1 0 0 1 1 1 1 GAGA binding protein-like family CCSAP PF15748.5 CDJ62669.1 - 0.0067 16.6 29.2 0.0067 16.6 29.2 2.5 3 0 0 3 3 3 1 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ62669.1 - 0.0076 16.1 26.8 0.015 15.1 26.8 1.5 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Exonuc_VII_L PF02601.15 CDJ62669.1 - 0.0088 15.6 18.1 0.012 15.2 18.1 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF2052 PF09747.9 CDJ62669.1 - 0.012 15.7 28.2 0.15 12.2 26.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SAPS PF04499.15 CDJ62669.1 - 0.036 12.9 15.2 0.068 11.9 15.2 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF572 PF04502.13 CDJ62669.1 - 0.34 10.5 27.3 0.019 14.6 19.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) SID-1_RNA_chan PF13965.6 CDJ62669.1 - 0.62 8.4 8.8 2.4 6.5 9.4 1.6 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 CDJ62669.1 - 1 8.1 45.0 0.51 9.1 40.4 2.0 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 CDJ62669.1 - 1 9.4 24.9 7 6.6 24.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 CDJ62669.1 - 1.1 7.5 52.4 1.9 6.7 52.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.9 CDJ62669.1 - 1.6 7.5 27.1 0.024 13.5 13.2 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Zip PF02535.22 CDJ62669.1 - 2.3 7.3 16.5 6.8 5.8 16.4 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter ALMT PF11744.8 CDJ62669.1 - 3.8 6.2 22.7 6.9 5.4 22.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ62669.1 - 4 6.3 34.8 8.3 5.3 34.8 1.4 1 0 0 1 1 1 0 Solute carrier family 12 LicD PF04991.13 CDJ62669.1 - 5.2 7.1 9.4 8.6 6.4 9.4 1.3 1 0 0 1 1 1 0 LicD family DUF913 PF06025.12 CDJ62669.1 - 9.5 5.1 18.8 1.2 8.0 12.7 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CCB2_CCB4 PF11152.8 CDJ62670.1 - 0.099 11.9 3.5 0.051 12.9 1.2 1.6 1 1 1 2 2 2 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 KASH PF10541.9 CDJ62670.1 - 0.12 12.6 6.7 0.12 12.7 2.4 2.4 2 0 0 2 2 2 0 Nuclear envelope localisation domain TFIIA PF03153.13 CDJ62670.1 - 1.4 8.8 14.5 2 8.4 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Bac_chlorC PF02043.17 CDJ62671.1 - 0.036 14.1 1.6 0.093 12.8 0.1 2.2 2 1 0 2 2 2 0 Bacteriochlorophyll C binding protein DUF572 PF04502.13 CDJ62672.1 - 0.18 11.4 17.7 0.25 11.0 17.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Tetraspanin PF00335.20 CDJ62672.1 - 0.25 11.0 2.7 0.32 10.7 2.7 1.2 1 0 0 1 1 1 0 Tetraspanin family Macoilin PF09726.9 CDJ62672.1 - 0.32 9.5 20.3 0.5 8.9 20.3 1.2 1 0 0 1 1 1 0 Macoilin family VIT1 PF01988.19 CDJ62672.1 - 0.56 10.0 8.2 0.041 13.8 2.8 1.8 2 0 0 2 2 2 0 VIT family Ribosomal_60s PF00428.19 CDJ62672.1 - 0.97 10.1 15.0 18 6.0 11.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glycogen_syn PF05693.13 CDJ62672.1 - 1.6 7.2 4.9 2.5 6.6 4.9 1.2 1 0 0 1 1 1 0 Glycogen synthase SPT16 PF08644.11 CDJ62672.1 - 4.2 7.6 10.0 7.1 6.8 10.0 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Det1 PF09737.9 CDJ62672.1 - 4.5 6.2 7.5 2.3 7.2 0.0 2.1 2 0 0 2 2 2 0 De-etiolated protein 1 Det1 Coatomer_WDAD PF04053.14 CDJ62673.1 - 1.3e-93 314.4 0.0 1.1e-76 258.7 0.0 2.4 2 1 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.32 CDJ62673.1 - 0.00088 20.0 0.0 0.18 12.8 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat K_channel_TID PF07941.11 CDJ62673.1 - 0.016 15.7 5.7 0.016 15.7 5.7 5.8 6 0 0 6 6 6 0 Potassium channel Kv1.4 tandem inactivation domain Sec16_C PF12931.7 CDJ62673.1 - 0.018 14.7 0.2 0.033 13.9 0.2 1.3 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 SR-25 PF10500.9 CDJ62673.1 - 2.2 7.8 21.8 3.4 7.2 19.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RT_RNaseH PF17917.1 CDJ62674.1 - 1.3e-18 67.2 0.5 3.2e-18 65.9 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ62674.1 - 1.1e-16 61.0 0.0 2.2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ62674.1 - 6e-07 29.4 0.0 2.4e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 CDJ62675.1 - 0.011 16.0 0.3 0.055 13.8 0.2 2.2 1 1 0 1 1 1 0 Retrotransposon gag protein Cofac_haem_bdg PF04187.13 CDJ62675.1 - 0.1 12.6 1.2 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN 40S_SA_C PF16122.5 CDJ62678.1 - 0.78 11.1 23.2 2.1 9.7 23.2 1.9 1 1 0 1 1 1 0 40S ribosomal protein SA C-terminus Androgen_recep PF02166.16 CDJ62678.1 - 4.9 5.9 12.6 5 5.9 12.6 1.0 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 CDJ62679.1 - 0.0078 16.3 50.4 0.0093 16.0 50.4 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF5427 PF10310.9 CDJ62679.1 - 1.1 8.2 31.1 1.4 7.8 31.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SRP-alpha_N PF04086.13 CDJ62679.1 - 3.8 7.4 34.2 4.6 7.1 34.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal HCO3_cotransp PF00955.21 CDJ62679.1 - 6.3 5.5 8.5 6.5 5.5 8.5 1.2 1 0 0 1 1 1 0 HCO3- transporter family DUF4175 PF13779.6 CDJ62679.1 - 9.3 4.0 56.4 11 3.8 56.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DEAD PF00270.29 CDJ62680.1 - 4.1e-43 147.2 0.0 5.9e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ62680.1 - 0.00072 19.6 0.0 0.0017 18.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDJ62680.1 - 0.0056 16.4 0.0 0.0097 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ62680.1 - 0.019 15.3 0.0 0.04 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 CDJ62680.1 - 0.021 14.2 0.0 0.12 11.7 0.0 2.1 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit RCC1 PF00415.18 CDJ62681.1 - 7.6e-25 87.3 16.0 3.2e-09 37.3 0.3 6.7 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ62681.1 - 4.1e-22 77.4 13.0 9.5e-08 31.7 0.0 5.2 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat UTP15_C PF09384.10 CDJ62682.1 - 7.9e-10 38.6 0.9 8.9e-10 38.4 0.9 1.0 1 0 0 1 1 1 1 UTP15 C terminal Utp12 PF04003.12 CDJ62682.1 - 0.0022 18.3 0.8 0.0024 18.2 0.8 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family SAPS PF04499.15 CDJ62683.1 - 0.73 8.6 6.2 0.95 8.2 6.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF572 PF04502.13 CDJ62683.1 - 0.98 9.0 12.5 1.3 8.6 12.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC27 PF09507.10 CDJ62683.1 - 1.6 8.0 20.0 2.6 7.3 20.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Plasmodium_Vir PF05795.11 CDJ62683.1 - 1.8 7.9 2.5 2 7.7 2.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein BSP_II PF05432.11 CDJ62683.1 - 2.7 7.6 8.2 3.2 7.3 8.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Paramyxo_ncap PF00973.19 CDJ62683.1 - 4.1 6.2 10.9 6.7 5.5 10.9 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein THOC2_N PF16134.5 CDJ62684.1 - 0.049 12.3 3.4 0.045 12.4 3.4 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Spt20 PF12090.8 CDJ62684.1 - 0.53 9.9 19.3 0.52 9.9 19.3 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ62684.1 - 4.7 7.1 18.9 4.5 7.1 18.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-H2C2_2 PF13465.6 CDJ62685.1 - 0.02 15.3 1.0 0.02 15.3 1.0 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDJ62685.1 - 0.021 15.6 1.1 0.039 14.8 1.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDJ62685.1 - 0.13 12.0 3.0 0.52 10.1 3.0 2.0 1 1 0 1 1 1 0 C2H2-type zinc-finger domain Apt1 PF10351.9 CDJ62686.1 - 7 5.4 23.8 0.019 13.9 8.8 2.5 2 1 0 2 2 2 0 Golgi-body localisation protein domain Dus PF01207.17 CDJ62687.1 - 0.00075 18.7 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NOB1_Zn_bind PF08772.11 CDJ62688.1 - 1.2e-18 67.0 0.6 1.9e-18 66.4 0.6 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 CDJ62688.1 - 1e-17 64.4 0.0 1.9e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 CDJ62688.1 - 0.052 13.2 1.5 2.6 7.8 0.1 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain SUIM_assoc PF16619.5 CDJ62688.1 - 0.062 13.4 8.2 0.087 12.9 4.4 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 OrfB_Zn_ribbon PF07282.11 CDJ62688.1 - 0.15 12.0 0.7 0.29 11.1 0.7 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.6 CDJ62688.1 - 0.19 11.7 2.0 4 7.4 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal DUF1980 PF09323.10 CDJ62688.1 - 0.26 11.2 0.8 0.41 10.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Spt20 PF12090.8 CDJ62688.1 - 7 6.2 9.3 6.1 6.4 7.6 1.8 2 0 0 2 2 2 0 Spt20 family HEAT PF02985.22 CDJ62689.1 - 0.074 13.3 12.0 4.1 7.9 0.2 6.7 5 0 0 5 5 5 0 HEAT repeat EF-hand_8 PF13833.6 CDJ62690.1 - 9.2e-08 31.8 0.8 2.5e-07 30.5 0.8 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ62690.1 - 2.6e-06 26.6 1.3 0.0012 18.2 0.3 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ62690.1 - 4.1e-06 27.2 1.5 7.1e-06 26.4 0.3 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ62690.1 - 0.00037 20.2 0.2 0.1 12.6 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CDJ62690.1 - 0.051 13.1 0.1 0.17 11.4 0.1 1.9 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 CDJ62690.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand PUB PF09409.10 CDJ62690.1 - 0.19 11.7 0.5 4.8 7.2 0.0 2.5 3 0 0 3 3 3 0 PUB domain ketoacyl-synt PF00109.26 CDJ62691.1 - 8.6e-17 61.6 0.0 1.4e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MCD_N PF17408.2 CDJ62691.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain PAT1 PF09770.9 CDJ62692.1 - 3 6.0 56.8 4 5.6 56.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mitofilin PF09731.9 CDJ62694.1 - 0.012 14.5 23.5 0.013 14.4 23.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Draxin PF15550.6 CDJ62694.1 - 0.1 12.4 8.7 0.14 12.0 8.7 1.2 1 0 0 1 1 1 0 Draxin NUDE_C PF04880.13 CDJ62694.1 - 0.14 12.7 7.6 0.18 12.3 7.6 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DDHD PF02862.17 CDJ62694.1 - 0.17 12.0 5.8 0.17 12.1 5.8 1.2 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 CDJ62694.1 - 0.34 9.6 13.7 0.35 9.6 13.7 1.2 1 0 0 1 1 1 0 Presenilin Rib_recp_KP_reg PF05104.12 CDJ62694.1 - 0.56 11.2 30.5 0.78 10.8 30.5 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region BORG_CEP PF14957.6 CDJ62694.1 - 0.58 11.3 5.5 0.66 11.1 5.5 1.3 1 0 0 1 1 1 0 Cdc42 effector TFIIA PF03153.13 CDJ62694.1 - 0.62 10.0 33.2 0.99 9.3 33.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ62694.1 - 0.79 9.1 12.3 0.83 9.1 12.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PTPRCAP PF15713.5 CDJ62694.1 - 1.3 9.3 15.4 1.7 9.0 15.4 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SOG2 PF10428.9 CDJ62694.1 - 1.4 8.0 11.0 1.4 8.0 11.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein PIG-S PF10510.9 CDJ62694.1 - 2.3 7.0 9.1 2.3 6.9 9.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Zip PF02535.22 CDJ62694.1 - 2.4 7.3 7.1 2.7 7.1 7.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Lin-8 PF03353.15 CDJ62694.1 - 3.2 7.2 17.4 3.4 7.2 17.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2052 PF09747.9 CDJ62694.1 - 4.8 7.3 16.2 5.5 7.1 16.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Ndc1_Nup PF09531.10 CDJ62694.1 - 7.7 5.1 14.9 8.1 5.0 14.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NPR3 PF03666.13 CDJ62694.1 - 7.9 5.1 12.4 8.7 5.0 12.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.16 CDJ62694.1 - 8.4 6.4 12.7 9.3 6.2 12.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.6 CDJ62694.1 - 8.9 6.5 14.0 12 6.1 14.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DEAD PF00270.29 CDJ62695.1 - 7.7e-05 22.5 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ras PF00071.22 CDJ62696.1 - 9.4e-16 57.8 0.3 1.1e-15 57.6 0.3 1.1 1 0 0 1 1 1 1 Ras family SMP_C2CD2L PF18696.1 CDJ62696.1 - 0.015 15.1 0.8 0.017 14.9 0.8 1.1 1 0 0 1 1 1 0 Synaptotagmin-like, mitochondrial and lipid-binding domain LppC PF04348.13 CDJ62696.1 - 0.047 12.5 0.4 0.055 12.3 0.4 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein RT_RNaseH PF17917.1 CDJ62697.1 - 1.1e-27 96.3 0.1 2.8e-27 95.1 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ62697.1 - 1.7e-27 95.3 0.1 3.7e-27 94.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ62697.1 - 2.2e-20 73.1 0.0 3.9e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ62697.1 - 3.2e-17 62.4 0.9 7.2e-17 61.2 0.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ62697.1 - 2.5e-16 59.9 0.0 8.4e-16 58.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ62697.1 - 6.8e-12 45.1 0.0 1.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 CDJ62697.1 - 1.5e-07 31.3 0.0 3.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ62697.1 - 5.7e-07 30.0 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ62697.1 - 6.7e-07 29.9 0.0 1.7e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 CDJ62697.1 - 0.0004 20.5 0.6 0.0014 18.8 0.3 2.0 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease PF09668.10 CDJ62697.1 - 0.032 14.0 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease rve_3 PF13683.6 CDJ62697.1 - 0.032 14.0 0.1 0.95 9.3 0.1 2.6 2 0 0 2 2 2 0 Integrase core domain RVT_3 PF13456.6 CDJ62697.1 - 0.049 13.4 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase-like RVP PF00077.20 CDJ62697.1 - 0.068 13.5 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Myosin_head PF00063.21 CDJ62698.1 - 1.1e-10 40.5 0.0 1.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) RAB3GAP2_N PF14655.6 CDJ62700.1 - 0.028 13.7 0.5 0.028 13.7 0.5 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SPX PF03105.19 CDJ62701.1 - 0.00026 21.0 2.1 0.00026 21.0 2.1 3.4 2 1 0 2 2 2 1 SPX domain SR-25 PF10500.9 CDJ62701.1 - 0.0056 16.3 13.2 0.0056 16.3 13.2 7.6 4 3 2 6 6 6 1 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ62701.1 - 0.0073 15.2 51.5 0.17 10.7 6.2 3.2 3 0 0 3 3 3 3 Golgi-body localisation protein domain DUF1645 PF07816.11 CDJ62701.1 - 0.021 15.4 1.2 0.021 15.4 1.2 6.9 4 3 1 5 5 5 0 Protein of unknown function (DUF1645) DnaJ PF00226.31 CDJ62703.1 - 3.4e-29 100.7 0.9 6.2e-29 99.9 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain COX4 PF02936.14 CDJ62703.1 - 0.017 15.1 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV GHMP_kinases_N PF00288.26 CDJ62703.1 - 0.081 13.2 0.5 0.081 13.2 0.5 2.0 2 0 0 2 2 2 0 GHMP kinases N terminal domain IMUP PF15761.5 CDJ62703.1 - 2 9.2 8.3 0.37 11.5 4.2 1.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF3446 PF11928.8 CDJ62703.1 - 2 8.8 11.4 8.7 6.7 7.9 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain Transposase_24 PF03004.14 CDJ62703.1 - 2.2 8.4 0.0 2.2 8.4 0.0 3.2 3 1 0 3 3 3 0 Plant transposase (Ptta/En/Spm family) FA_hydroxylase PF04116.13 CDJ62704.1 - 1.2e-16 61.2 11.8 2.2e-16 60.4 11.8 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.28 CDJ62704.1 - 1.1e-10 41.5 0.0 2.2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OTCace_N PF02729.21 CDJ62705.1 - 1.6e-34 119.1 0.0 1.6e-34 119.1 0.0 3.6 4 0 0 4 4 4 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 CDJ62705.1 - 5e-23 81.9 1.2 2.7e-21 76.3 0.0 4.2 3 2 1 5 5 5 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Collagen PF01391.18 CDJ62705.1 - 0.38 10.5 17.6 1.1 9.1 17.6 1.7 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) SR-25 PF10500.9 CDJ62709.1 - 2.8e-05 23.9 17.7 3.4e-05 23.6 17.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SelP_N PF04592.14 CDJ62709.1 - 0.033 13.6 20.4 0.037 13.4 20.4 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TAF1D PF15333.6 CDJ62709.1 - 0.095 12.4 9.3 0.12 12.1 9.3 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D TCP PF03634.13 CDJ62709.1 - 0.17 12.4 16.5 0.21 12.2 16.5 1.1 1 0 0 1 1 1 0 TCP family transcription factor DUF4603 PF15376.6 CDJ62709.1 - 0.24 8.8 12.4 0.26 8.6 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CCSAP PF15748.5 CDJ62709.1 - 0.36 11.0 18.1 0.41 10.8 18.1 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FAM91_C PF14648.6 CDJ62709.1 - 1.9 7.2 11.1 2 7.2 11.1 1.0 1 0 0 1 1 1 0 FAM91 C-terminus MAP70 PF07058.11 CDJ62709.1 - 4.1 6.0 10.9 4.3 6.0 10.9 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 FAM199X PF15814.5 CDJ62709.1 - 4.1 6.4 15.1 4.6 6.2 15.1 1.0 1 0 0 1 1 1 0 Protein family FAM199X Neur_chan_memb PF02932.16 CDJ62709.1 - 6.8 6.7 11.3 7.7 6.5 11.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FlgH PF02107.16 CDJ62709.1 - 7.5 6.1 14.9 12 5.4 14.9 1.3 1 1 0 1 1 1 0 Flagellar L-ring protein TFIIA PF03153.13 CDJ62709.1 - 8.5 6.3 25.8 12 5.8 25.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 CDJ62709.1 - 9.2 6.1 18.5 11 5.9 18.5 1.1 1 0 0 1 1 1 0 Velvet factor Helicase_C PF00271.31 CDJ62710.1 - 1.8e-08 34.7 0.3 4.8e-08 33.3 0.0 1.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DUF2722 PF10846.8 CDJ62710.1 - 0.00017 20.7 0.2 0.00017 20.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) NPFF PF15085.6 CDJ62710.1 - 0.011 16.0 6.9 0.02 15.2 6.9 1.4 1 0 0 1 1 1 0 Neuropeptide FF Spt20 PF12090.8 CDJ62710.1 - 0.024 14.3 10.5 0.031 13.9 10.5 1.2 1 0 0 1 1 1 0 Spt20 family RAB3GAP2_N PF14655.6 CDJ62710.1 - 0.21 10.8 2.5 0.29 10.4 2.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus 7tm_2 PF00002.24 CDJ62710.1 - 0.29 10.4 0.6 0.42 9.9 0.6 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Sec16 PF12932.7 CDJ62710.1 - 0.48 11.0 3.6 0.91 10.1 3.6 1.4 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region G0-G1_switch_2 PF15103.6 CDJ62710.1 - 0.53 10.7 3.7 8.6 6.8 0.0 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 Dymeclin PF09742.9 CDJ62710.1 - 0.89 7.9 5.1 2.3 6.5 1.0 2.0 2 0 0 2 2 2 0 Dyggve-Melchior-Clausen syndrome protein TFIIA PF03153.13 CDJ62710.1 - 0.89 9.5 10.6 1 9.2 10.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Focal_AT PF03623.13 CDJ62711.1 - 0.47 10.4 1.9 5.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Focal adhesion targeting region PGI PF00342.19 CDJ62718.1 - 2.9e-185 616.5 0.2 1e-121 406.9 0.0 2.0 2 0 0 2 2 2 2 Phosphoglucose isomerase DUF755 PF05501.11 CDJ62718.1 - 0.00043 20.6 18.0 0.00043 20.6 18.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF755) DUF1645 PF07816.11 CDJ62718.1 - 0.00044 20.9 6.2 0.00082 20.0 6.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) SPX PF03105.19 CDJ62718.1 - 0.004 17.1 0.2 0.004 17.1 0.2 1.5 2 0 0 2 2 2 1 SPX domain Herpes_capsid PF06112.11 CDJ62718.1 - 0.0042 17.2 6.6 0.0077 16.3 6.6 1.4 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein Spt20 PF12090.8 CDJ62718.1 - 0.008 15.8 13.1 0.015 14.9 13.1 1.4 1 0 0 1 1 1 1 Spt20 family Rrn6 PF10214.9 CDJ62718.1 - 0.016 13.7 11.8 0.023 13.2 11.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AF-4 PF05110.13 CDJ62718.1 - 0.039 12.0 13.1 0.057 11.5 13.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Androgen_recep PF02166.16 CDJ62718.1 - 0.056 12.3 16.3 0.087 11.7 16.3 1.2 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 CDJ62718.1 - 0.059 13.4 12.0 0.11 12.5 12.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ62718.1 - 0.2 10.6 4.3 0.31 10.0 4.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM199X PF15814.5 CDJ62718.1 - 0.26 10.3 7.9 0.65 9.0 7.9 1.6 1 0 0 1 1 1 0 Protein family FAM199X GREB1 PF15782.5 CDJ62718.1 - 0.33 8.0 5.0 0.43 7.6 5.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ62718.1 - 0.34 10.4 5.7 0.59 9.6 5.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TERB2 PF15101.6 CDJ62718.1 - 0.37 10.8 6.8 0.5 10.4 5.5 1.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Menin PF05053.13 CDJ62718.1 - 0.5 8.7 3.2 0.69 8.2 3.2 1.1 1 0 0 1 1 1 0 Menin DUF4667 PF15700.5 CDJ62718.1 - 0.52 10.4 11.3 0.96 9.5 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Miga PF10265.9 CDJ62718.1 - 0.66 8.9 5.9 1.2 8.1 5.9 1.3 1 0 0 1 1 1 0 Mitoguardin ANAPC_CDC26 PF10471.9 CDJ62718.1 - 1.7 9.6 21.0 4.9 8.1 21.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 XRN_M PF17846.1 CDJ62718.1 - 1.8 7.4 6.1 4.7 6.0 0.2 2.2 2 0 0 2 2 2 0 Xrn1 helical domain DUF2722 PF10846.8 CDJ62718.1 - 2.2 7.1 16.0 3.5 6.5 16.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Paf1 PF03985.13 CDJ62718.1 - 2.9 6.8 8.8 5.2 6.0 8.8 1.3 1 0 0 1 1 1 0 Paf1 IMUP PF15761.5 CDJ62718.1 - 4.5 8.0 12.7 11 6.8 12.7 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein BRF1 PF07741.13 CDJ62718.1 - 9.8 6.6 8.8 0.95 9.8 1.4 2.6 2 1 0 2 2 2 0 Brf1-like TBP-binding domain DAO PF01266.24 CDJ62719.1 - 6.7e-08 32.5 0.0 7e-07 29.2 0.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Mqo PF06039.15 CDJ62719.1 - 5.3e-07 28.5 0.0 6.8e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.6 CDJ62719.1 - 0.0048 16.2 0.0 0.0071 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GTP_EFTU_D3 PF03143.17 CDJ62720.1 - 2.3e-24 85.8 0.0 2.9e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PTS_2-RNA PF01885.16 CDJ62721.1 - 2.7e-41 141.6 0.0 5e-41 140.7 0.0 1.4 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Spt20 PF12090.8 CDJ62721.1 - 0.013 15.2 1.9 0.019 14.6 1.9 1.2 1 0 0 1 1 1 0 Spt20 family RAB3GAP2_N PF14655.6 CDJ62721.1 - 0.23 10.7 1.8 0.35 10.1 1.8 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Coatomer_WDAD PF04053.14 CDJ62721.1 - 0.43 9.6 2.2 0.65 9.0 2.2 1.2 1 0 0 1 1 1 0 Coatomer WD associated region SUIM_assoc PF16619.5 CDJ62721.1 - 1.6 8.9 14.1 0.12 12.4 8.4 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FAM222A PF15258.6 CDJ62722.1 - 0.041 13.0 15.6 0.053 12.6 15.6 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Ribosomal_60s PF00428.19 CDJ62722.1 - 3.5 8.3 9.3 0.98 10.1 3.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein CDK2AP PF09806.9 CDJ62722.1 - 4.3 7.3 17.8 7.6 6.5 17.8 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein TALPID3 PF15324.6 CDJ62722.1 - 7.4 4.1 20.2 10 3.7 20.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Pex14_N PF04695.13 CDJ62722.1 - 9.3 6.9 20.5 4.6 7.9 15.5 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAP2 PF01569.21 CDJ62723.1 - 0.27 11.0 2.8 1.7 8.4 0.2 3.8 4 0 0 4 4 4 0 PAP2 superfamily PT PF04886.12 CDJ62724.1 - 7.5e-05 22.2 5.7 7.5e-05 22.2 5.7 3.0 3 0 0 3 3 3 2 PT repeat V_ATPase_I PF01496.19 CDJ62724.1 - 0.23 9.3 4.1 0.35 8.7 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ62724.1 - 0.75 9.7 43.0 1.3 8.9 28.4 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ62724.1 - 1.6 8.9 8.2 0.67 10.1 2.3 2.3 2 0 0 2 2 2 0 DDHD domain Peptidase_S49_N PF08496.10 CDJ62724.1 - 2.1 8.4 8.0 5.6 7.0 8.0 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Glyco_hydro_44 PF12891.7 CDJ62724.1 - 2.2 8.2 4.6 0.77 9.7 1.1 1.8 2 0 0 2 2 2 0 Glycoside hydrolase family 44 DUF572 PF04502.13 CDJ62724.1 - 2.9 7.4 9.5 0.21 11.2 4.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) ALMT PF11744.8 CDJ62724.1 - 3.3 6.4 4.8 6 5.6 4.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 CDJ62725.1 - 0.0011 19.0 3.9 0.0011 19.0 3.9 3.7 4 1 0 4 4 4 2 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ62725.1 - 0.0014 19.0 7.2 0.0014 19.0 7.2 7.1 5 2 0 5 5 5 2 Anti-sigma-K factor rskA DUF374 PF04028.13 CDJ62725.1 - 0.012 15.1 0.3 0.19 11.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF374) Alb1 PF09135.11 CDJ62725.1 - 0.23 12.4 5.7 0.078 13.9 0.8 2.7 2 0 0 2 2 2 0 Alb1 Spt20 PF12090.8 CDJ62725.1 - 0.26 10.9 20.4 0.52 9.9 2.3 2.7 2 0 0 2 2 2 0 Spt20 family Band_3_cyto PF07565.13 CDJ62725.1 - 1.4 8.7 6.7 2.4 7.9 0.0 3.3 3 0 0 3 3 3 0 Band 3 cytoplasmic domain DUF4834 PF16118.5 CDJ62725.1 - 2.1 9.4 9.7 5 8.2 0.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF719 PF05334.13 CDJ62725.1 - 4.7 7.4 6.0 16 5.7 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Actin PF00022.19 CDJ62726.1 - 4.8e-40 137.4 3.6 1.3e-19 70.1 0.0 3.6 2 1 1 3 3 3 3 Actin Dehydrin PF00257.19 CDJ62726.1 - 0.018 15.6 2.9 0.018 15.6 2.9 6.3 4 2 1 6 6 6 0 Dehydrin HTH_6 PF01418.17 CDJ62726.1 - 0.027 14.4 0.6 17 5.4 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family NifU PF01106.17 CDJ62726.1 - 0.1 12.7 2.6 23 5.3 0.0 3.4 3 0 0 3 3 3 0 NifU-like domain Peptidase_C1 PF00112.23 CDJ62726.1 - 0.86 9.6 7.6 2.5 8.1 2.2 2.6 2 0 0 2 2 2 0 Papain family cysteine protease DUF1676 PF07898.13 CDJ62726.1 - 1.5 8.8 0.0 1.5 8.8 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1676) Carboxyl_trans PF01039.22 CDJ62727.1 - 0.099 11.2 2.8 0.11 11.1 2.8 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain DUF2207 PF09972.9 CDJ62728.1 - 0.73 8.5 1.9 17 4.0 2.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RskA PF10099.9 CDJ62729.1 - 0.00087 19.6 43.1 0.012 15.9 12.3 2.2 1 1 1 2 2 2 2 Anti-sigma-K factor rskA Activator_LAG-3 PF11498.8 CDJ62729.1 - 0.028 13.4 33.6 0.029 13.4 2.3 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF3446 PF11928.8 CDJ62729.1 - 0.81 10.0 0.0 0.81 10.0 0.0 3.2 2 1 0 2 2 2 0 Early growth response N-terminal domain BAF1_ABF1 PF04684.13 CDJ62729.1 - 1.1 8.2 17.4 1.6 7.7 9.8 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor FDF PF09532.10 CDJ62729.1 - 1.5 9.7 13.0 2.2 9.2 5.8 2.4 2 0 0 2 2 2 0 FDF domain DUF3682 PF12446.8 CDJ62729.1 - 3 8.3 38.3 1.9 9.0 15.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Med15 PF09606.10 CDJ62729.1 - 3.2 6.3 43.3 0.99 8.0 40.3 1.4 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FHIPEP PF00771.20 CDJ62729.1 - 4.2 5.7 5.2 13 4.1 1.5 2.2 2 0 0 2 2 2 0 FHIPEP family EIIBC-GUT_N PF03612.14 CDJ62729.1 - 7.8 6.2 12.0 3.1 7.5 1.1 2.4 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus ASF1_hist_chap PF04729.13 CDJ62731.1 - 4.8e-23 81.8 0.4 8.3e-21 74.5 0.4 2.3 1 1 0 1 1 1 1 ASF1 like histone chaperone Apt1 PF10351.9 CDJ62731.1 - 0.14 11.0 13.6 0.21 10.4 13.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ62731.1 - 0.73 9.7 19.0 0.9 9.4 19.0 1.1 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 CDJ62731.1 - 2.1 7.0 11.1 2.8 6.6 11.1 1.2 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 CDJ62731.1 - 2.8 7.7 7.1 3.8 7.2 7.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TFIIA PF03153.13 CDJ62731.1 - 3.5 7.5 22.6 4.6 7.1 22.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 CDJ62731.1 - 5.1 6.4 4.8 5.9 6.2 4.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4551 PF15087.6 CDJ62731.1 - 7.4 5.3 16.0 9.1 5.0 16.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) rve PF00665.26 CDJ62732.1 - 9.8e-06 25.8 0.0 1.2e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain ATP-synt_ab PF00006.25 CDJ62735.1 - 1.4e-26 93.5 3.0 3.5e-21 75.8 0.6 4.1 4 0 0 4 4 4 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CDJ62735.1 - 2.8e-13 50.3 0.0 1.4e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain SR-25 PF10500.9 CDJ62736.1 - 0.0089 15.7 0.8 0.0089 15.7 0.8 9.4 5 3 3 8 8 8 3 Nuclear RNA-splicing-associated protein DUF5113 PF17140.4 CDJ62736.1 - 0.0096 15.7 2.6 0.0096 15.7 2.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5113) RNA_pol_I_A49 PF06870.12 CDJ62737.1 - 2.4e-06 26.7 0.1 4e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Activator_LAG-3 PF11498.8 CDJ62737.1 - 2.2 7.2 12.3 3.1 6.7 12.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ISN1 PF06437.11 CDJ62739.1 - 4.6e-65 220.1 0.0 3.6e-41 141.4 0.0 2.3 2 0 0 2 2 2 2 IMP-specific 5'-nucleotidase Hydrolase_3 PF08282.12 CDJ62739.1 - 0.1 12.3 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SUIM_assoc PF16619.5 CDJ62739.1 - 6.2 7.0 17.9 11 6.2 1.9 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 adh_short PF00106.25 CDJ62741.1 - 2.4e-13 50.0 16.0 1.1e-06 28.3 0.1 4.6 4 1 1 5 5 5 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ62741.1 - 5e-08 32.8 5.1 1.5e-06 27.9 0.2 4.4 3 1 0 4 4 4 2 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 CDJ62741.1 - 2.3 8.0 7.2 0.26 11.1 0.4 2.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Med3 PF11593.8 CDJ62742.1 - 0.013 14.8 13.2 0.018 14.3 13.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Rpp20 PF12328.8 CDJ62742.1 - 5 7.1 8.8 3.5 7.6 6.9 1.7 1 1 1 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Afi1 PF07792.12 CDJ62745.1 - 0.0039 17.7 0.2 0.0057 17.1 0.2 1.2 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DDHD PF02862.17 CDJ62745.1 - 0.011 15.9 0.2 0.014 15.6 0.2 1.2 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 CDJ62745.1 - 0.053 12.3 7.7 0.073 11.8 7.7 1.1 1 0 0 1 1 1 0 Presenilin PIEZO PF15917.5 CDJ62745.1 - 0.26 10.7 19.3 0.58 9.6 19.3 1.5 1 0 0 1 1 1 0 Piezo CPSF100_C PF13299.6 CDJ62745.1 - 0.34 11.1 3.8 0.61 10.2 3.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal OATP PF03137.20 CDJ62745.1 - 0.77 8.0 2.1 1 7.5 2.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CTU2 PF10288.9 CDJ62745.1 - 2 8.7 12.4 3.3 8.0 12.4 1.3 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 CDC45 PF02724.14 CDJ62745.1 - 2.6 6.2 8.6 3.5 5.8 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ62745.1 - 2.7 7.7 11.0 3.9 7.2 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Folate_carrier PF01770.18 CDJ62745.1 - 3.2 6.4 4.2 4.4 5.9 4.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF2333 PF10095.9 CDJ62745.1 - 4.7 6.1 6.4 6.6 5.6 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Connexin PF00029.19 CDJ62745.1 - 9.3 5.9 7.3 15 5.3 7.3 1.2 1 0 0 1 1 1 0 Connexin EcsC PF12787.7 CDJ62746.1 - 0.023 14.4 1.9 0.025 14.3 1.9 1.1 1 0 0 1 1 1 0 EcsC protein family Androgen_recep PF02166.16 CDJ62746.1 - 0.19 10.5 20.5 0.23 10.3 20.5 1.2 1 0 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 CDJ62746.1 - 1.1 8.9 15.9 1.2 8.7 15.9 1.0 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ62746.1 - 2.4 8.0 6.6 2.2 8.2 6.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SesA PF17107.5 CDJ62748.1 - 0.54 10.5 7.3 17 5.6 0.7 3.8 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases GCN5L1 PF06320.13 CDJ62748.1 - 1.5 9.0 5.8 1.5 9.0 0.7 2.7 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) SR-25 PF10500.9 CDJ62748.1 - 2.7 7.6 6.0 5.6 6.5 6.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ62748.1 - 4.4 7.7 10.5 3.2 8.1 3.0 2.9 2 0 0 2 2 2 0 Early growth response N-terminal domain IMUP PF15761.5 CDJ62748.1 - 6 7.6 9.6 0.21 12.3 2.8 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein DASH_Dad3 PF08656.10 CDJ62749.1 - 0.029 14.5 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 DASH complex subunit Dad3 CLP1_N PF16573.5 CDJ62750.1 - 0.004 17.3 0.1 0.005 17.0 0.1 1.2 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor RsbU_N PF08673.10 CDJ62751.1 - 2.3e-06 27.6 40.5 0.14 12.3 5.1 6.7 1 1 5 6 6 6 6 Phosphoserine phosphatase RsbU, N-terminal domain GDPD PF03009.17 CDJ62751.1 - 2.2 8.0 5.6 17 5.0 0.4 2.8 1 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family SUIM_assoc PF16619.5 CDJ62752.1 - 0.013 15.5 3.7 0.048 13.7 3.7 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DLIC PF05783.11 CDJ62752.1 - 2.3 7.0 9.1 0.55 9.0 0.5 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Suf PF05843.14 CDJ62753.1 - 0.8 9.6 5.0 0.36 10.8 2.7 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Transketolase_C PF02780.20 CDJ62755.1 - 8.2e-38 129.1 0.1 9.2e-38 128.9 0.1 1.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain ETF PF01012.21 CDJ62755.1 - 0.13 12.1 3.3 0.18 11.7 3.3 1.1 1 0 0 1 1 1 0 Electron transfer flavoprotein domain zf-met PF12874.7 CDJ62756.1 - 8.9e-06 25.9 0.4 8.9e-06 25.9 0.4 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Dehydrin PF00257.19 CDJ62756.1 - 0.0017 18.9 0.8 0.0017 18.9 0.8 4.8 3 2 1 4 4 4 1 Dehydrin zf-C2H2_jaz PF12171.8 CDJ62756.1 - 0.0048 17.2 2.8 0.0048 17.2 2.8 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.12 CDJ62756.1 - 0.069 13.4 2.5 0.15 12.3 2.5 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) TFIIA PF03153.13 CDJ62758.1 - 7e-09 36.2 92.6 0.00017 21.8 20.8 3.1 3 0 0 3 3 3 3 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ62758.1 - 0.0035 17.7 7.8 0.0035 17.7 7.8 5.4 3 2 1 4 4 4 2 Anti-sigma-K factor rskA DDHD PF02862.17 CDJ62758.1 - 0.065 13.4 26.3 0.25 11.5 7.1 3.3 3 0 0 3 3 3 0 DDHD domain Pex14_N PF04695.13 CDJ62758.1 - 0.31 11.7 62.1 0.051 14.2 16.6 3.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 CDJ62758.1 - 2.2 6.4 63.9 0.11 10.7 23.0 3.0 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 Afi1 PF07792.12 CDJ62758.1 - 2.8 8.4 22.1 1.3 9.5 10.2 3.2 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NEMP PF10225.9 CDJ62758.1 - 5 6.7 22.2 0.8 9.3 1.1 3.3 3 0 0 3 3 3 0 NEMP family HEAT_EZ PF13513.6 CDJ62759.1 - 0.036 14.6 1.0 0.036 14.6 1.0 5.2 3 2 2 6 6 6 0 HEAT-like repeat SR-25 PF10500.9 CDJ62759.1 - 0.2 11.3 17.2 0.099 12.2 15.0 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ62759.1 - 0.63 8.8 9.0 0.84 8.4 9.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain BAF1_ABF1 PF04684.13 CDJ62759.1 - 1.9 7.5 13.3 3 6.8 13.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SPX PF03105.19 CDJ62759.1 - 2.2 8.1 16.3 2.9 7.7 16.3 1.2 1 0 0 1 1 1 0 SPX domain SOBP PF15279.6 CDJ62759.1 - 2.5 8.6 13.2 3.4 8.2 13.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF572 PF04502.13 CDJ62759.1 - 2.7 7.5 14.7 3.2 7.3 14.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ndc1_Nup PF09531.10 CDJ62759.1 - 6.1 5.4 16.8 9.9 4.7 16.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1645 PF07816.11 CDJ62759.1 - 9.7 6.7 19.7 32 5.0 19.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) Metallophos PF00149.28 CDJ62760.1 - 0.017 15.6 0.1 0.03 14.8 0.1 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos PF00149.28 CDJ62761.1 - 2.4e-06 28.2 0.0 4.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RskA PF10099.9 CDJ62762.1 - 0.22 11.8 12.4 0.29 11.4 12.4 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ62762.1 - 3.1 7.7 10.5 3.3 7.6 10.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPR_2 PF13041.6 CDJ62763.1 - 6.5e-49 163.9 0.0 2.1e-09 37.4 0.0 8.1 4 3 5 9 9 9 7 PPR repeat family PPR_1 PF12854.7 CDJ62763.1 - 4.4e-31 106.3 0.9 0.00083 19.0 0.0 9.3 9 1 0 9 9 9 7 PPR repeat PPR PF01535.20 CDJ62763.1 - 8e-29 97.9 5.4 0.00011 22.2 0.0 10.0 11 0 0 11 11 11 5 PPR repeat PPR_3 PF13812.6 CDJ62763.1 - 2.3e-24 85.2 0.0 1.9e-06 27.9 0.0 6.7 4 2 3 7 7 7 6 Pentatricopeptide repeat domain PPR_long PF17177.4 CDJ62763.1 - 2.6e-13 49.8 2.9 8.2e-05 22.1 0.1 5.2 1 1 2 5 5 5 3 Pentacotripeptide-repeat region of PRORP SUIM_assoc PF16619.5 CDJ62763.1 - 0.014 15.4 0.9 0.014 15.4 0.9 9.1 6 3 0 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 EOS1 PF12326.8 CDJ62763.1 - 0.052 13.5 1.9 6.6 6.6 0.0 2.7 2 0 0 2 2 2 0 N-glycosylation protein JHD PF17811.1 CDJ62763.1 - 1.6 9.3 0.0 1.6 9.3 0.0 4.3 5 0 0 5 5 5 0 Jumonji helical domain HCNGP PF07818.13 CDJ62764.1 - 4.9e-05 23.9 0.0 6.6e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 HCNGP-like protein eIF-3_zeta PF05091.12 CDJ62765.1 - 0.018 14.1 20.3 0.018 14.0 20.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIIBC-GUT_N PF03612.14 CDJ62765.1 - 0.019 14.7 11.3 0.021 14.6 11.3 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RAG1_imp_bd PF12560.8 CDJ62765.1 - 0.024 14.2 7.8 0.025 14.1 7.8 1.1 1 0 0 1 1 1 0 RAG1 importin binding Rxt3 PF08642.10 CDJ62765.1 - 0.034 14.9 4.0 0.039 14.7 4.0 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF5308 PF17233.2 CDJ62765.1 - 0.038 14.2 12.5 0.045 14.0 12.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) CPSF100_C PF13299.6 CDJ62765.1 - 0.04 14.1 11.3 0.041 14.1 11.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CDJ62765.1 - 0.052 12.3 17.2 0.055 12.2 17.2 1.0 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 CDJ62765.1 - 0.053 13.7 12.7 0.054 13.6 12.7 1.1 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 CDJ62765.1 - 0.059 12.3 7.4 0.059 12.4 7.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4820 PF16091.5 CDJ62765.1 - 0.06 12.7 9.4 0.077 12.4 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) EOS1 PF12326.8 CDJ62765.1 - 0.099 12.6 7.0 0.1 12.5 7.0 1.1 1 0 0 1 1 1 0 N-glycosylation protein MecA PF05389.12 CDJ62765.1 - 0.1 12.2 12.7 0.11 12.1 12.7 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Pex14_N PF04695.13 CDJ62765.1 - 0.11 13.2 27.1 0.11 13.1 27.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ62765.1 - 0.12 12.3 41.6 0.13 12.3 41.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ62765.1 - 0.14 11.6 18.7 0.15 11.5 18.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF5523 PF17661.1 CDJ62765.1 - 0.17 11.6 17.8 0.19 11.4 17.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CCDC53 PF10152.9 CDJ62765.1 - 0.19 12.2 16.6 0.19 12.1 16.6 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4407 PF14362.6 CDJ62765.1 - 0.26 10.6 18.3 0.27 10.6 18.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAT1 PF09770.9 CDJ62765.1 - 0.29 9.4 27.6 0.28 9.4 27.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ62765.1 - 0.29 10.9 16.5 0.32 10.8 16.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.15 CDJ62765.1 - 0.31 9.9 9.6 0.32 9.9 9.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Connexin PF00029.19 CDJ62765.1 - 0.33 10.7 14.1 0.41 10.4 14.1 1.1 1 0 0 1 1 1 0 Connexin DUF2126 PF09899.9 CDJ62765.1 - 0.39 8.7 11.3 0.37 8.8 11.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2828 PF11443.8 CDJ62765.1 - 0.41 8.7 15.5 0.44 8.6 15.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CDC45 PF02724.14 CDJ62765.1 - 0.41 8.9 12.1 0.46 8.7 12.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Rrn6 PF10214.9 CDJ62765.1 - 0.43 9.0 19.7 0.47 8.9 19.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FAM60A PF15396.6 CDJ62765.1 - 0.48 10.4 11.7 0.53 10.3 11.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CSG2 PF16965.5 CDJ62765.1 - 0.52 9.2 9.4 0.56 9.1 9.4 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator PGA_cap PF09587.10 CDJ62765.1 - 0.54 9.7 4.8 0.58 9.6 4.8 1.1 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Pannexin_like PF12534.8 CDJ62765.1 - 0.55 9.3 11.6 0.52 9.4 11.6 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Pal1 PF08316.11 CDJ62765.1 - 0.61 10.8 8.1 0.71 10.6 8.1 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Utp21 PF04192.12 CDJ62765.1 - 0.62 9.5 17.9 0.78 9.2 17.9 1.1 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Band_3_cyto PF07565.13 CDJ62765.1 - 0.62 9.8 15.3 0.67 9.7 15.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 CDJ62765.1 - 0.74 9.8 12.1 0.75 9.8 12.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Baculo_PP31 PF05311.11 CDJ62765.1 - 0.79 9.2 15.9 0.89 9.0 15.9 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Cellulose_synt PF03552.14 CDJ62765.1 - 0.82 8.1 5.6 0.77 8.2 5.6 1.0 1 0 0 1 1 1 0 Cellulose synthase BORG_CEP PF14957.6 CDJ62765.1 - 0.85 10.8 10.0 0.94 10.7 10.0 1.1 1 0 0 1 1 1 0 Cdc42 effector Tim54 PF11711.8 CDJ62765.1 - 0.9 8.2 16.1 1 8.1 16.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Afi1 PF07792.12 CDJ62765.1 - 0.91 10.0 17.0 1 9.8 17.0 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3408 PF11888.8 CDJ62765.1 - 1.1 9.5 18.0 1.3 9.2 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SLC12 PF03522.15 CDJ62765.1 - 1.1 8.2 17.4 1.3 7.9 17.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 BRF1 PF07741.13 CDJ62765.1 - 1.2 9.5 14.3 1.6 9.1 14.3 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain ALMT PF11744.8 CDJ62765.1 - 1.2 7.9 13.5 1.3 7.7 13.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter PPL5 PF18168.1 CDJ62765.1 - 1.2 8.3 12.1 1.5 8.1 12.1 1.0 1 0 0 1 1 1 0 Prim-pol family 5 CLN3 PF02487.17 CDJ62765.1 - 1.3 8.0 14.7 1.5 7.8 14.7 1.0 1 0 0 1 1 1 0 CLN3 protein Gti1_Pac2 PF09729.9 CDJ62765.1 - 1.3 9.1 14.4 1.4 8.9 14.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family YABBY PF04690.13 CDJ62765.1 - 1.3 9.5 13.4 1.5 9.4 13.4 1.1 1 0 0 1 1 1 0 YABBY protein Tmp39 PF10271.9 CDJ62765.1 - 1.4 7.9 8.8 1.7 7.6 8.8 1.0 1 0 0 1 1 1 0 Putative transmembrane protein TERB2 PF15101.6 CDJ62765.1 - 1.5 8.8 26.7 1.9 8.5 26.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 V_ATPase_I PF01496.19 CDJ62765.1 - 1.6 6.6 20.2 1.9 6.3 20.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ABC2_membrane_2 PF12679.7 CDJ62765.1 - 1.6 8.0 8.2 1.6 8.0 8.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein OATP PF03137.20 CDJ62765.1 - 1.6 6.9 14.4 2.1 6.6 14.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Pex26 PF07163.12 CDJ62765.1 - 1.7 7.9 16.5 2.2 7.5 16.5 1.3 1 0 0 1 1 1 0 Pex26 protein PTPRCAP PF15713.5 CDJ62765.1 - 1.7 8.9 17.8 2 8.7 17.8 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Peptidase_S49_N PF08496.10 CDJ62765.1 - 1.8 8.6 15.7 2.1 8.4 15.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Plasmodium_Vir PF05795.11 CDJ62765.1 - 1.9 7.8 9.6 2 7.8 9.6 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MMM1 PF10296.9 CDJ62765.1 - 1.9 7.5 14.1 2.2 7.2 14.1 1.0 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 FAM91_C PF14648.6 CDJ62765.1 - 2 7.1 13.3 2.5 6.8 13.3 1.0 1 0 0 1 1 1 0 FAM91 C-terminus DUF4746 PF15928.5 CDJ62765.1 - 2.1 7.7 13.7 2.3 7.6 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF853 PF05872.12 CDJ62765.1 - 2.2 6.8 13.5 2.5 6.6 13.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Folate_carrier PF01770.18 CDJ62765.1 - 2.3 6.9 11.6 2.3 6.8 11.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier ATAD4 PF15321.6 CDJ62765.1 - 2.6 9.4 12.3 3.7 8.9 12.3 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 SID-1_RNA_chan PF13965.6 CDJ62765.1 - 3 6.2 11.8 3.6 5.9 11.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HemX PF04375.14 CDJ62765.1 - 3 7.1 35.5 3.6 6.8 35.5 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase EPL1 PF10513.9 CDJ62765.1 - 3 8.2 19.6 3.8 7.9 19.6 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF2072 PF09845.9 CDJ62765.1 - 3 8.1 15.2 4 7.7 15.2 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein RPA43_OB PF17875.1 CDJ62765.1 - 3.1 8.4 13.2 3.9 8.1 13.2 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I GREB1 PF15782.5 CDJ62765.1 - 3.4 4.6 16.6 3.2 4.7 16.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Kei1 PF08552.11 CDJ62765.1 - 3.5 7.5 13.3 4.1 7.2 13.3 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Scs3p PF10261.9 CDJ62765.1 - 3.5 7.1 6.5 4.2 6.8 6.5 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM AIF_C PF14721.6 CDJ62765.1 - 3.7 7.9 17.5 4.7 7.6 17.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FHIPEP PF00771.20 CDJ62765.1 - 3.9 5.8 12.3 4.9 5.5 12.3 1.1 1 0 0 1 1 1 0 FHIPEP family Paf1 PF03985.13 CDJ62765.1 - 4 6.3 21.2 4.6 6.1 21.2 1.0 1 0 0 1 1 1 0 Paf1 Membralin PF09746.9 CDJ62765.1 - 4.1 6.4 12.3 4.3 6.3 12.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein G0-G1_switch_2 PF15103.6 CDJ62765.1 - 4.3 7.8 14.8 5.8 7.4 14.8 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 FAM176 PF14851.6 CDJ62765.1 - 4.6 6.9 13.7 6.4 6.4 13.7 1.1 1 0 0 1 1 1 0 FAM176 family DUF868 PF05910.12 CDJ62765.1 - 4.7 6.8 12.6 5.3 6.6 12.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) Eapp_C PF10238.9 CDJ62765.1 - 4.9 7.2 22.1 7.6 6.6 22.1 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein TFB6 PF17110.5 CDJ62765.1 - 5.3 6.8 12.7 6.3 6.5 12.7 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Hid1 PF12722.7 CDJ62765.1 - 5.4 5.0 17.8 5.7 4.9 17.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UPF0560 PF10577.9 CDJ62765.1 - 5.8 5.3 28.2 6.4 5.1 28.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ctr PF04145.15 CDJ62765.1 - 5.9 7.5 11.9 7.3 7.2 11.9 1.1 1 0 0 1 1 1 0 Ctr copper transporter family HCO3_cotransp PF00955.21 CDJ62765.1 - 5.9 5.6 9.8 6.2 5.5 9.8 1.0 1 0 0 1 1 1 0 HCO3- transporter family GOLD_2 PF13897.6 CDJ62765.1 - 6 7.4 6.0 7.3 7.1 6.0 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PIP5K PF01504.18 CDJ62765.1 - 6.3 5.9 17.6 7.7 5.6 17.6 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase GNAT_acetyltr_2 PF13718.6 CDJ62765.1 - 7.1 6.0 13.1 9.1 5.6 13.1 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Hydin_ADK PF17213.3 CDJ62765.1 - 7.2 6.8 13.8 11 6.2 13.8 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MMR1 PF08505.10 CDJ62765.1 - 7.4 6.8 23.2 9.2 6.5 23.2 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Peroxin-13_N PF04088.13 CDJ62765.1 - 7.8 6.8 12.1 10 6.4 12.1 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF702 PF05142.12 CDJ62765.1 - 8.9 6.8 20.2 12 6.4 20.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) CBP_BcsG PF11658.8 CDJ62765.1 - 9.8 4.4 16.3 11 4.3 16.3 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG PRC2_HTH_1 PF18118.1 CDJ62765.1 - 9.9 7.0 15.7 13 6.7 15.7 1.1 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Peptidase_C1 PF00112.23 CDJ62766.1 - 4.4e-34 118.5 16.3 2.3e-14 54.0 0.7 4.8 3 1 1 4 4 4 3 Papain family cysteine protease CathepsinC_exc PF08773.11 CDJ62766.1 - 2e-08 34.6 7.4 3.5e-08 33.7 0.1 3.8 2 1 0 2 2 2 1 Cathepsin C exclusion domain Propeptide_C1 PF08127.13 CDJ62766.1 - 0.0011 18.8 1.3 0.0021 17.9 1.3 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide SPX PF03105.19 CDJ62766.1 - 0.0025 17.8 6.2 0.0025 17.8 6.2 1.9 2 0 0 2 2 2 1 SPX domain RNase_H2_suC PF08615.11 CDJ62766.1 - 0.013 15.6 0.2 0.025 14.7 0.2 1.5 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Peroxin-13_N PF04088.13 CDJ62766.1 - 0.03 14.6 0.4 0.03 14.6 0.4 2.6 3 0 0 3 3 3 0 Peroxin 13, N-terminal region DUF778 PF05608.12 CDJ62766.1 - 0.038 14.4 3.3 0.13 12.6 2.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF778) RskA PF10099.9 CDJ62766.1 - 0.17 12.2 32.3 1.2 9.4 2.7 3.4 2 1 1 3 3 3 0 Anti-sigma-K factor rskA CIAPIN1 PF05093.13 CDJ62766.1 - 0.17 12.4 7.7 4.3 7.9 3.1 3.1 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF4770 PF15994.5 CDJ62766.1 - 0.2 11.9 12.7 0.015 15.5 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Med15 PF09606.10 CDJ62766.1 - 0.22 10.1 37.7 0.004 15.9 30.4 1.7 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 CDJ62766.1 - 0.35 9.6 14.6 0.74 8.5 14.6 1.5 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ62766.1 - 1.2 9.2 9.3 3 7.8 9.3 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EPL1 PF10513.9 CDJ62766.1 - 1.7 9.0 12.6 0.28 11.6 6.0 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like Band_3_cyto PF07565.13 CDJ62766.1 - 2.3 8.0 10.0 0.14 11.9 3.0 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2126 PF09899.9 CDJ62766.1 - 2.7 6.0 7.2 4.1 5.4 7.2 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SpoIIP PF07454.11 CDJ62766.1 - 4.1 6.8 13.6 0.067 12.6 5.7 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF1645 PF07816.11 CDJ62766.1 - 4.7 7.7 19.7 2 9.0 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) Connexin PF00029.19 CDJ62766.1 - 9.4 5.9 7.6 0.74 9.5 2.6 1.6 2 0 0 2 2 2 0 Connexin Prominin PF05478.11 CDJ62767.1 - 0.73 7.7 6.0 0.98 7.3 6.0 1.1 1 0 0 1 1 1 0 Prominin Antistasin PF02822.14 CDJ62772.1 - 0.062 13.9 28.5 6.7 7.5 0.4 9.2 7 3 1 8 8 8 0 Antistasin family FOG_N PF15888.5 CDJ62772.1 - 0.2 12.0 36.3 1.8 9.0 0.8 9.7 9 1 2 11 11 11 0 Folded gastrulation N-terminus EB PF01683.18 CDJ62772.1 - 0.49 10.7 46.9 4.4 7.7 3.1 10.3 7 3 1 8 8 8 0 EB module CCDC53 PF10152.9 CDJ62773.1 - 0.017 15.5 2.8 0.019 15.4 2.8 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4179 PF13786.6 CDJ62773.1 - 0.025 15.1 0.1 0.025 15.1 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) R_equi_Vir PF05526.11 CDJ62773.1 - 0.25 11.2 2.1 0.34 10.8 2.1 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RskA PF10099.9 CDJ62773.1 - 4.6 7.5 19.3 7.1 6.9 19.3 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA GCP_N_terminal PF17681.1 CDJ62775.1 - 1.7e-20 73.9 0.0 3.8e-18 66.1 0.0 2.7 2 1 0 2 2 2 2 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CDJ62775.1 - 5e-17 62.3 0.0 1.5e-16 60.8 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal SART-1 PF03343.13 CDJ62777.1 - 0.043 12.4 45.4 0.056 12.0 45.4 1.0 1 0 0 1 1 1 0 SART-1 family AAA_lid_3 PF17862.1 CDJ62778.1 - 4.3e-11 42.4 0.1 8.3e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain Peptidase_M41 PF01434.18 CDJ62778.1 - 7.6e-10 38.9 0.3 1.3e-09 38.2 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CDJ62778.1 - 3.6e-06 27.4 0.0 1e-05 26.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ62778.1 - 7.5e-05 23.2 1.3 0.00012 22.5 1.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ62778.1 - 0.00063 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ62778.1 - 0.00065 20.0 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SPX PF03105.19 CDJ62778.1 - 0.0037 17.2 3.8 0.0041 17.1 3.8 1.1 1 0 0 1 1 1 1 SPX domain RuvB_N PF05496.12 CDJ62778.1 - 0.0057 16.4 0.0 0.015 15.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CDJ62778.1 - 0.0059 15.9 0.0 0.0093 15.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CDJ62778.1 - 0.0084 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CDJ62778.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDJ62778.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CDJ62778.1 - 0.018 15.6 0.0 0.05 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDJ62778.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ62778.1 - 0.048 12.9 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 CDJ62778.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CDJ62778.1 - 0.069 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CDJ62778.1 - 0.086 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 CDJ62778.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 CDJ62778.1 - 0.22 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Apt1 PF10351.9 CDJ62778.1 - 0.24 10.2 7.6 0.34 9.7 7.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 CDJ62778.1 - 0.38 10.7 10.7 0.55 10.2 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 CDJ62778.1 - 3.6 6.0 10.1 4.4 5.7 10.1 1.1 1 0 0 1 1 1 0 Macoilin family Mannitol_dh_C PF08125.13 CDJ62779.1 - 2.2e-37 128.9 0.0 2.2e-37 128.9 0.0 1.7 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain DUF2722 PF10846.8 CDJ62779.1 - 0.0035 16.4 0.8 0.0036 16.3 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Mannitol_dh PF01232.23 CDJ62779.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 1 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain CrgA PF06781.12 CDJ62779.1 - 0.21 11.7 0.3 0.36 10.9 0.3 1.3 1 0 0 1 1 1 0 Cell division protein CrgA SUIM_assoc PF16619.5 CDJ62779.1 - 0.57 10.3 14.8 1.4 9.1 14.8 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ62779.1 - 0.64 9.6 12.1 1 8.9 12.1 1.3 1 0 0 1 1 1 0 Spt20 family UPF0560 PF10577.9 CDJ62779.1 - 2.8 6.3 6.3 3.7 5.9 6.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4834 PF16118.5 CDJ62779.1 - 2.8 9.0 5.8 4.4 8.3 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SID-1_RNA_chan PF13965.6 CDJ62780.1 - 0.5 8.7 2.2 0.54 8.6 2.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TraT PF05818.12 CDJ62780.1 - 0.57 9.8 20.3 1.1 8.9 20.3 1.6 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein Apt1 PF10351.9 CDJ62780.1 - 3.9 6.2 14.8 4 6.2 14.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ62780.1 - 4.7 5.9 15.2 5.2 5.7 15.2 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ62780.1 - 6.6 6.5 9.9 7.1 6.4 9.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4202 PF13875.6 CDJ62781.1 - 0.093 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) SH3_15 PF18346.1 CDJ62781.1 - 0.096 13.0 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain Apt1 PF10351.9 CDJ62781.1 - 0.16 10.8 2.7 0.19 10.6 2.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain rve_3 PF13683.6 CDJ62781.1 - 0.2 11.5 1.3 0.31 10.9 1.3 1.3 1 0 0 1 1 1 0 Integrase core domain Secretin_N_2 PF07655.13 CDJ62781.1 - 0.22 12.1 11.8 0.33 11.5 11.8 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Macoilin PF09726.9 CDJ62781.1 - 0.47 8.9 3.4 0.43 9.1 3.4 1.1 1 0 0 1 1 1 0 Macoilin family RSRP PF17069.5 CDJ62781.1 - 7.9 6.0 19.7 10 5.6 19.7 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 UNC-50 PF05216.13 CDJ62782.1 - 1.3e-12 47.7 0.3 2.8e-12 46.7 0.3 1.5 1 0 0 1 1 1 1 UNC-50 family Presenilin PF01080.17 CDJ62782.1 - 0.14 10.9 33.7 0.2 10.4 33.7 1.3 1 0 0 1 1 1 0 Presenilin Caldesmon PF02029.15 CDJ62782.1 - 0.2 10.4 31.2 0.25 10.1 31.2 1.0 1 0 0 1 1 1 0 Caldesmon FAM60A PF15396.6 CDJ62782.1 - 0.59 10.1 21.0 0.83 9.6 21.0 1.4 1 0 0 1 1 1 0 Protein Family FAM60A ALMT PF11744.8 CDJ62782.1 - 1.2 7.9 20.4 1.7 7.4 20.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter SAGA-Tad1 PF12767.7 CDJ62782.1 - 1.7 8.3 25.1 2.4 7.8 25.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Macoilin PF09726.9 CDJ62782.1 - 2 6.9 21.9 3.3 6.2 21.9 1.3 1 0 0 1 1 1 0 Macoilin family DUF4045 PF13254.6 CDJ62782.1 - 2.5 7.6 28.5 3.9 7.0 28.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) AF-4 PF05110.13 CDJ62782.1 - 2.9 5.9 39.6 3.8 5.5 39.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Lin-8 PF03353.15 CDJ62782.1 - 2.9 7.4 32.5 5.3 6.5 32.5 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 CDJ62782.1 - 3.3 6.7 30.7 4.3 6.2 30.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MDM10 PF12519.8 CDJ62782.1 - 3.8 6.3 23.1 4.9 5.9 23.1 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 NPR3 PF03666.13 CDJ62782.1 - 6.3 5.5 30.2 8.4 5.1 30.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 CDJ62782.1 - 8.3 4.6 28.8 11 4.2 28.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Membralin PF09746.9 CDJ62782.1 - 8.7 5.3 17.3 12 4.9 17.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein LAP1C PF05609.12 CDJ62782.1 - 9.9 5.1 30.5 14 4.6 30.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Cpn60_TCP1 PF00118.24 CDJ62783.1 - 2.5e-145 484.9 6.6 3.9e-75 253.3 0.1 2.2 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family ETRAMP PF09716.10 CDJ62783.1 - 0.078 13.1 0.0 0.3 11.2 0.0 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Asparaginase_C PF17763.1 CDJ62783.1 - 0.61 10.3 6.9 1.7 8.9 5.8 2.2 1 1 1 2 2 2 0 Glutaminase/Asparaginase C-terminal domain bMG3 PF11974.8 CDJ62783.1 - 2.3 8.3 6.5 1.2 9.1 0.0 2.6 2 1 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain SPX PF03105.19 CDJ62784.1 - 0.0017 18.3 1.3 0.0018 18.2 1.3 1.2 1 0 0 1 1 1 1 SPX domain MAP65_ASE1 PF03999.12 CDJ62784.1 - 0.47 9.1 2.5 0.56 8.8 2.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SR-25 PF10500.9 CDJ62784.1 - 0.54 9.8 16.5 0.91 9.1 16.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ62784.1 - 1.6 7.5 5.0 2 7.2 5.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC106 PF15794.5 CDJ62784.1 - 8.7 6.0 8.7 14 5.3 8.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Shadoo PF14999.6 CDJ62785.1 - 0.11 12.6 8.8 0.18 11.9 8.8 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Endonuc_Holl PF10107.9 CDJ62786.1 - 0.0046 16.8 4.3 0.0046 16.8 4.3 1.9 2 0 0 2 2 2 1 Endonuclease related to archaeal Holliday junction resolvase PBP1_TM PF14812.6 CDJ62786.1 - 0.58 10.6 7.5 0.069 13.5 2.3 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CNDH2_M PF16869.5 CDJ62786.1 - 1 10.0 16.5 2.9 8.6 16.5 1.6 1 1 0 1 1 1 0 PF16858 Presenilin PF01080.17 CDJ62786.1 - 2.2 7.0 19.8 2.6 6.7 19.8 1.1 1 0 0 1 1 1 0 Presenilin CDH1_2_SANT_HL1 PF18375.1 CDJ62786.1 - 4 8.2 10.4 4.8 7.9 0.5 2.2 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Spt20 PF12090.8 CDJ62786.1 - 5.1 6.6 57.7 2.6 7.6 31.8 2.1 2 0 0 2 2 2 0 Spt20 family FAM176 PF14851.6 CDJ62786.1 - 6.4 6.4 12.8 0.35 10.5 2.7 2.1 2 0 0 2 2 2 0 FAM176 family XRN_M PF17846.1 CDJ62786.1 - 7.8 5.3 12.3 9.3 5.1 12.3 1.0 1 0 0 1 1 1 0 Xrn1 helical domain PP2C PF00481.21 CDJ62787.1 - 2.7e-08 33.8 1.7 4e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C Tyrosinase PF00264.20 CDJ62787.1 - 0.047 14.0 0.7 0.074 13.3 0.7 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase SOG2 PF10428.9 CDJ62787.1 - 0.048 12.9 10.3 0.053 12.7 10.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_hydro_42 PF02449.15 CDJ62787.1 - 0.074 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Apt1 PF10351.9 CDJ62787.1 - 0.094 11.6 5.3 0.098 11.5 5.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mem_trans PF03547.18 CDJ62787.1 - 1.1 7.6 4.9 1.5 7.1 4.9 1.1 1 0 0 1 1 1 0 Membrane transport protein GREB1 PF15782.5 CDJ62787.1 - 1.1 6.2 8.1 1.2 6.2 8.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM60A PF15396.6 CDJ62787.1 - 1.8 8.6 6.5 0.88 9.5 3.7 1.8 2 0 0 2 2 2 0 Protein Family FAM60A Miga PF10265.9 CDJ62787.1 - 4.4 6.2 8.8 6 5.7 8.8 1.1 1 0 0 1 1 1 0 Mitoguardin Neur_chan_memb PF02932.16 CDJ62787.1 - 5.3 7.0 4.4 2.4 8.1 2.5 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Lin-8 PF03353.15 CDJ62787.1 - 6.3 6.3 9.9 0.62 9.6 5.7 1.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF1387 PF07139.11 CDJ62787.1 - 6.9 6.3 12.2 1.9 8.2 8.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) ORC6 PF05460.13 CDJ62788.1 - 0.0038 16.5 5.1 0.0047 16.3 5.1 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) TFIIA PF03153.13 CDJ62788.1 - 0.023 14.7 16.9 0.023 14.7 16.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spc7_N PF15402.6 CDJ62788.1 - 0.025 12.8 5.1 0.031 12.5 5.1 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 SpoIIP PF07454.11 CDJ62788.1 - 0.17 11.3 3.1 0.18 11.3 3.1 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) STAC2_u1 PF16664.5 CDJ62788.1 - 0.19 12.2 5.8 0.28 11.7 5.8 1.2 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 CDC45 PF02724.14 CDJ62788.1 - 0.2 9.9 4.8 0.19 10.0 4.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Androgen_recep PF02166.16 CDJ62788.1 - 0.3 9.9 23.1 0.38 9.5 23.1 1.2 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 CDJ62788.1 - 0.48 9.1 8.2 0.53 9.0 8.2 1.0 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ62788.1 - 0.64 10.7 14.7 0.85 10.3 14.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.16 CDJ62788.1 - 0.92 9.5 4.3 1 9.4 4.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SprA-related PF12118.8 CDJ62788.1 - 1.2 8.2 21.5 1.5 7.9 21.5 1.0 1 0 0 1 1 1 0 SprA-related family Ndc1_Nup PF09531.10 CDJ62788.1 - 1.4 7.5 4.9 1.4 7.5 4.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4834 PF16118.5 CDJ62788.1 - 1.9 9.5 10.2 2.6 9.1 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM199X PF15814.5 CDJ62788.1 - 2 7.4 6.1 2.5 7.1 6.1 1.0 1 0 0 1 1 1 0 Protein family FAM199X Baculo_PP31 PF05311.11 CDJ62788.1 - 2.1 7.8 8.5 2.5 7.5 8.5 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Spt20 PF12090.8 CDJ62788.1 - 3.2 7.3 26.8 4 7.0 26.8 1.1 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 CDJ62788.1 - 3.2 6.6 11.6 3.5 6.5 11.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ62788.1 - 3.8 7.5 11.1 4.6 7.2 11.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4175 PF13779.6 CDJ62788.1 - 5.6 4.7 21.5 5.9 4.7 21.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) LIM_bind PF01803.16 CDJ62788.1 - 6.1 6.3 9.5 7.9 5.9 9.5 1.1 1 0 0 1 1 1 0 LIM-domain binding protein Suf PF05843.14 CDJ62788.1 - 8 6.3 12.1 9.6 6.1 12.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LSM PF01423.22 CDJ62789.1 - 2.5e-16 59.1 0.0 4.6e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 LSM domain Suf PF05843.14 CDJ62789.1 - 0.00066 19.8 6.5 0.00066 19.8 6.5 2.5 2 1 1 3 3 2 1 Suppressor of forked protein (Suf) MASE4 PF17158.4 CDJ62789.1 - 0.029 13.6 2.5 0.044 13.0 2.5 1.2 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain SM-ATX PF14438.6 CDJ62789.1 - 0.047 13.8 0.9 0.098 12.8 0.0 1.9 2 0 0 2 2 2 0 Ataxin 2 SM domain eIF-3_zeta PF05091.12 CDJ62789.1 - 0.17 10.8 18.2 0.014 14.4 11.3 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3292 PF11696.8 CDJ62789.1 - 0.23 9.8 3.8 0.39 9.0 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Consortin_C PF15281.6 CDJ62789.1 - 0.35 10.9 4.6 0.081 12.9 0.8 2.0 2 0 0 2 2 2 0 Consortin C-terminus Peptidase_U57 PF05582.12 CDJ62789.1 - 1.3 8.3 6.6 0.11 11.7 2.0 1.5 2 0 0 2 2 2 0 YabG peptidase U57 SpoIIP PF07454.11 CDJ62789.1 - 2.4 7.6 10.9 0.12 11.9 4.4 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Rxt3 PF08642.10 CDJ62789.1 - 4.1 8.2 9.2 2.2 9.1 4.9 2.2 2 1 0 2 2 2 0 Histone deacetylation protein Rxt3 eIF_4EBP PF05456.11 CDJ62789.1 - 4.2 7.3 9.7 29 4.6 7.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Orf78 PF06024.12 CDJ62789.1 - 4.7 7.6 16.3 0.054 13.8 3.6 2.9 2 1 1 3 3 3 0 Orf78 (ac78) RskA PF10099.9 CDJ62790.1 - 0.0083 16.4 7.0 0.0083 16.4 7.0 6.5 1 1 3 4 4 1 1 Anti-sigma-K factor rskA DUF4775 PF16001.5 CDJ62790.1 - 1.1 8.7 19.0 0.018 14.5 8.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4775) DUF913 PF06025.12 CDJ62790.1 - 2.6 6.9 16.0 7.4 5.4 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Hamartin PF04388.12 CDJ62790.1 - 3.1 6.4 40.1 0.0028 16.4 28.9 1.5 2 0 0 2 2 1 0 Hamartin protein SpoIIP PF07454.11 CDJ62790.1 - 4.5 6.6 22.0 1.5 8.2 15.3 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Coilin_N PF15862.5 CDJ62790.1 - 4.6 7.1 25.0 1.1 9.0 14.3 2.8 2 1 0 2 2 2 0 Coilin N-terminus NST1 PF13945.6 CDJ62790.1 - 5.3 7.1 31.5 8.4 6.5 1.8 2.9 2 0 0 2 2 2 0 Salt tolerance down-regulator Presenilin PF01080.17 CDJ62790.1 - 6.6 5.4 30.2 2.4 6.8 21.8 2.4 2 0 0 2 2 2 0 Presenilin SID-1_RNA_chan PF13965.6 CDJ62790.1 - 7.4 4.9 6.8 37 2.5 7.4 1.7 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 EOS1 PF12326.8 CDJ62790.1 - 7.8 6.4 11.6 33 4.3 8.3 2.5 2 1 0 2 2 2 0 N-glycosylation protein DUF2464 PF10240.9 CDJ62790.1 - 9.7 5.7 13.3 62 3.0 11.9 2.2 2 0 0 2 2 2 0 Multivesicular body subunit 12 ELMO_CED12 PF04727.13 CDJ62791.1 - 1.5e-25 90.3 1.3 1.5e-25 90.3 1.3 2.9 4 0 0 4 4 4 1 ELMO/CED-12 family RskA PF10099.9 CDJ62791.1 - 0.00021 21.7 1.4 0.00021 21.7 1.4 11.5 4 3 5 11 11 11 2 Anti-sigma-K factor rskA Lin-8 PF03353.15 CDJ62791.1 - 0.005 16.4 0.6 0.005 16.4 0.6 5.6 4 2 1 5 5 5 1 Ras-mediated vulval-induction antagonist TCP PF03634.13 CDJ62791.1 - 0.39 11.3 0.0 0.39 11.3 0.0 7.5 4 2 3 7 7 7 0 TCP family transcription factor Spt20 PF12090.8 CDJ62792.1 - 0.0004 20.1 1.4 0.0004 20.1 1.4 2.2 2 0 0 2 2 2 1 Spt20 family SDA1 PF05285.12 CDJ62792.1 - 0.016 14.6 15.6 0.039 13.4 10.0 2.1 2 0 0 2 2 2 0 SDA1 FA_desaturase PF00487.24 CDJ62792.1 - 0.16 11.8 0.6 16 5.2 0.1 2.2 2 0 0 2 2 2 0 Fatty acid desaturase DUF4834 PF16118.5 CDJ62792.1 - 0.26 12.2 0.2 0.26 12.2 0.2 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) PIG-U PF06728.13 CDJ62792.1 - 1.4 7.8 11.3 0.93 8.5 7.9 1.9 1 1 1 2 2 2 0 GPI transamidase subunit PIG-U Nop14 PF04147.12 CDJ62792.1 - 9.6 4.3 8.5 3.5 5.7 5.4 1.7 2 0 0 2 2 2 0 Nop14-like family SR-25 PF10500.9 CDJ62793.1 - 0.0005 19.7 6.2 0.0005 19.7 6.2 7.6 7 1 1 8 8 8 2 Nuclear RNA-splicing-associated protein TPR_2 PF07719.17 CDJ62793.1 - 0.0029 17.6 12.1 1.1 9.5 2.5 4.4 3 0 0 3 3 3 3 Tetratricopeptide repeat SID-1_RNA_chan PF13965.6 CDJ62793.1 - 2 6.7 6.1 12 4.1 0.1 3.6 4 0 0 4 4 4 0 dsRNA-gated channel SID-1 DUF1645 PF07816.11 CDJ62794.1 - 0.078 13.5 4.9 0.094 13.3 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) NPL4 PF05021.15 CDJ62794.1 - 0.14 11.5 0.0 0.14 11.5 0.0 1.0 1 0 0 1 1 1 0 NPL4 family AAA_23 PF13476.6 CDJ62795.1 - 0.16 12.5 24.1 0.21 12.1 24.1 1.2 1 0 0 1 1 1 0 AAA domain LAP1C PF05609.12 CDJ62795.1 - 0.18 10.9 37.7 0.23 10.5 37.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SDA1 PF05285.12 CDJ62796.1 - 2e-07 30.8 9.6 2.5e-07 30.4 9.6 1.3 1 0 0 1 1 1 1 SDA1 Velvet PF11754.8 CDJ62796.1 - 0.0069 16.4 11.0 0.0069 16.4 11.0 1.7 2 0 0 2 2 2 1 Velvet factor Drc1-Sld2 PF11719.8 CDJ62796.1 - 0.0079 15.8 18.1 0.011 15.3 18.1 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein Nop14 PF04147.12 CDJ62796.1 - 0.011 14.0 24.0 0.014 13.6 24.0 1.1 1 0 0 1 1 1 0 Nop14-like family Hamartin PF04388.12 CDJ62796.1 - 0.04 12.6 16.6 0.0078 14.9 13.2 1.4 2 0 0 2 2 2 0 Hamartin protein Merozoite_SPAM PF07133.11 CDJ62796.1 - 0.051 13.6 33.2 0.077 13.0 33.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Vfa1 PF08432.10 CDJ62796.1 - 0.12 12.7 28.4 0.22 11.8 28.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Raftlin PF15250.6 CDJ62796.1 - 0.22 10.2 18.1 0.0076 15.0 11.7 1.7 2 0 0 2 2 2 0 Raftlin RR_TM4-6 PF06459.12 CDJ62796.1 - 0.34 10.7 27.9 0.67 9.7 27.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BORG_CEP PF14957.6 CDJ62796.1 - 0.37 12.0 17.7 2.3 9.4 14.5 2.3 2 0 0 2 2 2 0 Cdc42 effector NPR3 PF03666.13 CDJ62796.1 - 0.41 9.4 24.2 0.77 8.5 24.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Endostatin PF06482.11 CDJ62796.1 - 0.49 9.8 16.1 0.84 9.0 16.1 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin ALMT PF11744.8 CDJ62796.1 - 0.78 8.5 17.5 1.1 8.0 17.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4045 PF13254.6 CDJ62796.1 - 0.79 9.3 20.5 0.03 14.0 14.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Hid1 PF12722.7 CDJ62796.1 - 0.84 7.7 23.8 1.2 7.1 23.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2828 PF11443.8 CDJ62796.1 - 0.9 7.6 17.2 1.3 7.0 17.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PAT1 PF09770.9 CDJ62796.1 - 0.99 7.6 31.9 1.5 7.0 31.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 CDJ62796.1 - 1.8 7.5 25.6 2.9 6.8 25.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Membralin PF09746.9 CDJ62796.1 - 1.9 7.5 11.1 2.5 7.1 11.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein Presenilin PF01080.17 CDJ62796.1 - 2 7.1 34.9 0.072 11.8 28.5 1.6 2 0 0 2 2 2 0 Presenilin Pox_Ag35 PF03286.14 CDJ62796.1 - 2.5 7.9 22.0 4.8 6.9 22.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Caldesmon PF02029.15 CDJ62796.1 - 2.5 6.8 35.0 3.6 6.3 35.0 1.2 1 0 0 1 1 1 0 Caldesmon AAA_11 PF13086.6 CDJ62796.1 - 2.5 7.8 21.9 4.3 7.0 21.9 1.4 1 0 0 1 1 1 0 AAA domain DUF913 PF06025.12 CDJ62796.1 - 2.7 6.9 16.4 0.5 9.3 12.2 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.6 CDJ62796.1 - 3.2 6.0 8.6 5.6 5.3 8.6 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GAGA_bind PF06217.12 CDJ62796.1 - 3.5 7.8 14.6 5.4 7.2 14.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2151 PF10221.9 CDJ62796.1 - 3.5 6.1 14.1 4.8 5.7 14.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4175 PF13779.6 CDJ62796.1 - 4.7 5.0 61.0 6.6 4.5 61.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Band_3_cyto PF07565.13 CDJ62796.1 - 6.2 6.5 19.0 14 5.3 19.0 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RRN3 PF05327.11 CDJ62796.1 - 6.2 5.2 19.1 9.7 4.6 19.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Rtf2 PF04641.12 CDJ62796.1 - 6.5 6.0 24.7 14 4.9 24.7 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger VIR_N PF15912.5 CDJ62796.1 - 6.7 6.2 22.1 9.3 5.8 22.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CDC45 PF02724.14 CDJ62796.1 - 7 4.8 32.8 5.2 5.2 31.4 1.4 2 0 0 2 2 2 0 CDC45-like protein HCO3_cotransp PF00955.21 CDJ62796.1 - 8 5.2 5.0 11 4.7 5.0 1.2 1 0 0 1 1 1 0 HCO3- transporter family FemAB PF02388.16 CDJ62796.1 - 8.6 5.1 19.0 12 4.6 19.0 1.2 1 0 0 1 1 1 0 FemAB family Lin-8 PF03353.15 CDJ62796.1 - 8.7 5.8 35.2 0.75 9.3 29.6 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 CDJ62797.1 - 0.12 11.7 16.2 0.15 11.4 16.2 1.1 1 0 0 1 1 1 0 SDA1 SPX PF03105.19 CDJ62797.1 - 0.18 11.7 23.8 0.21 11.4 23.8 1.2 1 0 0 1 1 1 0 SPX domain Mcm10 PF09332.11 CDJ62797.1 - 0.23 10.8 26.3 0.31 10.4 26.3 1.1 1 0 0 1 1 1 0 Mcm10 replication factor CDC45 PF02724.14 CDJ62797.1 - 0.35 9.1 14.3 0.4 8.9 14.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 CDJ62797.1 - 0.44 9.3 24.8 0.47 9.2 24.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 CDJ62797.1 - 0.66 7.7 18.8 0.73 7.5 18.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MPM1 PF17234.2 CDJ62797.1 - 0.99 9.6 15.7 1.6 9.0 15.7 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 NPR3 PF03666.13 CDJ62797.1 - 1.1 8.0 18.2 1.2 7.9 18.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 CDJ62797.1 - 1.1 7.4 13.2 1.2 7.2 13.2 1.0 1 0 0 1 1 1 0 Nop14-like family SLC12 PF03522.15 CDJ62797.1 - 1.6 7.7 17.0 1.7 7.6 17.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 CDJ62797.1 - 1.9 7.2 16.7 2.1 7.0 16.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF966 PF06136.13 CDJ62797.1 - 3.9 7.1 29.5 4.8 6.8 29.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Miga PF10265.9 CDJ62797.1 - 4.3 6.2 22.4 4.9 6.0 22.4 1.1 1 0 0 1 1 1 0 Mitoguardin HSD3 PF15244.6 CDJ62797.1 - 6.7 6.1 23.9 7.2 6.0 23.9 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 AF-4 PF05110.13 CDJ62797.1 - 7 4.6 39.9 9.2 4.2 39.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Membralin PF09746.9 CDJ62797.1 - 7.7 5.4 9.8 8.3 5.3 9.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF3253 PF11625.8 CDJ62798.1 - 0.022 15.0 0.3 0.1 12.8 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) SUIM_assoc PF16619.5 CDJ62798.1 - 0.054 13.6 35.7 0.33 11.1 6.7 4.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF4667 PF15700.5 CDJ62798.1 - 0.27 11.3 0.0 0.27 11.3 0.0 4.8 3 2 0 4 4 4 0 Domain of unknown function (DUF4667) DUF2650 PF10853.8 CDJ62798.1 - 7.2 6.4 7.4 42 4.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) Pkinase PF00069.25 CDJ62799.1 - 2.7e-39 135.1 0.0 5.8e-13 48.8 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ62799.1 - 1.8e-21 76.6 0.0 4e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ62799.1 - 4.9e-06 25.7 0.0 0.017 14.6 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDJ62799.1 - 7.3e-05 23.1 0.0 1.5 9.3 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ62799.1 - 0.00083 19.1 0.3 2.2 8.4 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ62799.1 - 0.073 12.9 0.1 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 CDJ62799.1 - 0.088 12.3 0.3 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 EF hand BSP_II PF05432.11 CDJ62799.1 - 9.4 5.8 8.6 0.64 9.7 3.0 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) HIT PF01230.23 CDJ62800.1 - 5.1e-22 78.4 0.1 6.8e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDJ62800.1 - 4.7e-10 39.9 0.0 5.6e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Orexin PF02072.15 CDJ62800.1 - 0.036 14.0 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Prepro-orexin AAA PF00004.29 CDJ62801.1 - 8.3e-94 311.0 0.0 1.5e-46 158.1 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ62801.1 - 5e-24 83.8 13.1 1.3e-13 50.5 0.6 3.5 3 1 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 CDJ62801.1 - 2.2e-21 75.8 0.8 5.1e-21 74.7 0.8 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CDJ62801.1 - 1.2e-13 51.2 0.0 5e-06 26.3 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ62801.1 - 1.7e-12 48.0 0.4 0.00054 20.4 0.1 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 CDJ62801.1 - 2.6e-11 43.9 0.0 2.1e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CDJ62801.1 - 1.5e-10 41.4 0.0 5.5e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CDJ62801.1 - 2.6e-10 40.4 0.1 3.7e-05 23.8 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 CDJ62801.1 - 1.4e-09 37.6 0.0 3.4e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 CDJ62801.1 - 5.3e-09 36.5 0.2 0.073 13.3 0.0 4.0 2 2 2 4 4 3 2 AAA domain TIP49 PF06068.13 CDJ62801.1 - 1.6e-08 34.2 0.0 0.00076 18.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 CDJ62801.1 - 1.2e-07 31.8 0.0 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CDJ62801.1 - 2.7e-07 31.2 0.0 0.03 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CDJ62801.1 - 5.8e-07 29.1 0.3 0.038 13.4 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDJ62801.1 - 8.5e-07 29.3 0.0 0.019 15.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 CDJ62801.1 - 1.1e-06 28.4 0.8 0.81 9.2 0.0 3.9 3 1 0 4 4 4 2 AAA domain Vps4_C PF09336.10 CDJ62801.1 - 1.1e-06 28.5 0.1 0.0007 19.5 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 CDJ62801.1 - 1.3e-05 25.0 0.0 0.18 11.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 CDJ62801.1 - 3.5e-05 23.8 0.1 0.65 9.9 0.1 3.2 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_28 PF13521.6 CDJ62801.1 - 3.9e-05 24.0 0.0 0.46 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CDJ62801.1 - 4.6e-05 23.0 0.0 0.35 10.3 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 CDJ62801.1 - 4.9e-05 23.3 0.1 0.53 10.2 0.0 3.4 2 1 0 3 3 3 2 NACHT domain ATPase PF06745.13 CDJ62801.1 - 5.3e-05 22.7 0.1 2.5 7.4 0.0 3.3 3 0 0 3 3 3 2 KaiC ABC_tran PF00005.27 CDJ62801.1 - 5.3e-05 23.7 0.0 0.29 11.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_17 PF13207.6 CDJ62801.1 - 5.7e-05 23.6 0.0 0.18 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CDJ62801.1 - 9.9e-05 22.1 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CDJ62801.1 - 0.00016 21.5 0.0 0.016 14.9 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 CDJ62801.1 - 0.00017 21.6 0.0 0.93 9.5 0.0 2.8 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 CDJ62801.1 - 0.00022 20.4 0.0 0.55 9.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 CDJ62801.1 - 0.00038 19.7 0.0 0.87 8.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.26 CDJ62801.1 - 0.00057 19.6 0.0 1.4 8.6 0.0 3.4 2 2 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 CDJ62801.1 - 0.00077 18.8 0.0 0.81 8.9 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Sigma54_activ_2 PF14532.6 CDJ62801.1 - 0.00092 19.3 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 CDJ62801.1 - 0.0011 18.2 0.0 0.4 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 CDJ62801.1 - 0.002 18.0 0.0 0.88 9.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein Rad17 PF03215.15 CDJ62801.1 - 0.0021 18.0 0.0 0.87 9.5 0.0 2.8 2 1 1 3 3 2 1 Rad17 P-loop domain PhoH PF02562.16 CDJ62801.1 - 0.0026 17.2 0.2 1.9 7.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 CDJ62801.1 - 0.0027 17.6 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 CDJ62801.1 - 0.0055 16.9 0.1 2.4 8.3 0.0 2.9 3 0 0 3 3 3 1 Cytidylate kinase-like family ResIII PF04851.15 CDJ62801.1 - 0.0066 16.5 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CDJ62801.1 - 0.0088 15.3 0.0 0.89 8.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 CDJ62801.1 - 0.017 15.0 1.1 13 5.7 0.0 3.8 4 0 0 4 4 3 0 NTPase AAA_19 PF13245.6 CDJ62801.1 - 0.02 15.2 1.2 6.9 7.0 0.1 3.3 3 1 1 4 4 2 0 AAA domain KAP_NTPase PF07693.14 CDJ62801.1 - 0.024 13.9 0.1 3.4 6.8 0.0 3.3 2 2 2 4 4 4 0 KAP family P-loop domain AAA_30 PF13604.6 CDJ62801.1 - 0.025 14.3 0.1 6.5 6.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 CDJ62801.1 - 0.035 14.2 0.1 18 5.4 0.0 3.0 3 0 0 3 3 3 0 Shikimate kinase AAA_11 PF13086.6 CDJ62801.1 - 0.049 13.4 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 CDJ62801.1 - 0.065 13.0 0.1 8.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase UFD1 PF03152.14 CDJ62801.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 TniB PF05621.11 CDJ62801.1 - 0.18 11.2 0.1 14 5.1 0.0 3.2 4 0 0 4 4 3 0 Bacterial TniB protein AAA_29 PF13555.6 CDJ62801.1 - 0.23 11.2 2.5 6.1 6.7 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain VTC PF09359.10 CDJ62803.1 - 4.1e-65 219.9 0.0 1e-62 212.1 0.0 2.2 1 1 0 1 1 1 1 VTC domain DUF202 PF02656.15 CDJ62803.1 - 7.5e-05 23.1 0.5 0.00021 21.7 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Ureide_permease PF07168.11 CDJ62804.1 - 1.1 8.0 1.9 1.5 7.5 1.9 1.1 1 0 0 1 1 1 0 Ureide permease Ribosomal_L6 PF00347.23 CDJ62805.1 - 4e-25 88.3 1.3 3.6e-14 53.2 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF4795 PF16043.5 CDJ62805.1 - 0.14 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DnaJ PF00226.31 CDJ62806.1 - 2.5e-08 33.9 0.0 6.5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 CDJ62806.1 - 0.14 12.3 2.2 0.53 10.5 2.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ62806.1 - 8.5 6.4 8.5 0.57 10.1 1.8 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PHM7_cyt PF14703.6 CDJ62807.1 - 0.00018 21.8 1.0 0.12 12.6 0.8 2.1 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter E1-N PF14463.6 CDJ62808.1 - 0.64 9.8 7.1 0.034 14.0 0.6 2.2 3 0 0 3 3 3 0 E1 N-terminal domain Mito_carr PF00153.27 CDJ62809.1 - 3.3e-45 152.0 5.0 3.5e-16 58.9 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpb4 PF03874.16 CDJ62811.1 - 2.2e-09 37.7 0.0 3.2e-09 37.2 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF2870 PF11069.8 CDJ62813.1 - 1.1e-32 112.3 0.2 2.6e-32 111.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) ubiquitin PF00240.23 CDJ62813.1 - 0.00012 21.8 0.2 8.3 6.2 0.0 3.5 3 0 0 3 3 3 3 Ubiquitin family Type2_restr_D3 PF16902.5 CDJ62813.1 - 0.15 12.0 1.2 0.29 11.1 0.4 1.9 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain PSA_CBD PF18341.1 CDJ62813.1 - 0.17 11.9 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 PSA endolysin C-terminal cell wall binding domain DUF1180 PF06679.12 CDJ62814.1 - 0.07 13.6 2.0 0.11 12.9 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF515 PF04415.12 CDJ62814.1 - 5.9 5.2 11.8 8.6 4.6 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PDZ_3 PF17815.1 CDJ62816.1 - 2.9e-41 140.7 0.2 6.5e-40 136.3 0.1 2.2 2 0 0 2 2 2 1 PDZ domain Trypsin_2 PF13365.6 CDJ62816.1 - 3.8e-08 34.4 3.8 0.00072 20.5 0.0 3.2 2 1 1 3 3 3 2 Trypsin-like peptidase domain Trypsin PF00089.26 CDJ62816.1 - 4.8e-06 26.5 2.4 0.008 16.0 0.3 2.6 1 1 0 2 2 2 2 Trypsin PDZ_2 PF13180.6 CDJ62816.1 - 1.7e-05 25.0 0.1 0.00016 22.0 0.1 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CDJ62816.1 - 0.079 12.8 0.2 0.82 9.6 0.0 2.5 2 0 0 2 2 2 0 PDZ domain MMR_HSR1 PF01926.23 CDJ62817.1 - 3.4e-17 62.6 0.1 3.4e-14 52.9 0.0 2.8 2 1 1 3 3 3 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.11 CDJ62817.1 - 2.1e-10 40.6 8.4 2.1e-10 40.6 8.4 3.9 2 2 2 4 4 4 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.18 CDJ62817.1 - 4.1e-09 36.2 0.0 2.7e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDJ62817.1 - 7.6e-06 25.9 1.3 0.014 15.3 0.1 3.9 4 0 0 4 4 4 1 RsgA GTPase GTP_EFTU PF00009.27 CDJ62817.1 - 0.0015 18.1 3.4 0.098 12.2 0.0 4.2 3 3 2 5 5 5 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CDJ62817.1 - 0.0056 17.1 0.0 0.0056 17.1 0.0 4.0 3 1 0 3 3 2 1 AAA ATPase domain Dynamin_N PF00350.23 CDJ62817.1 - 0.045 13.8 14.1 0.34 11.0 0.1 4.3 3 2 1 4 4 4 0 Dynamin family DUF687 PF05095.12 CDJ62817.1 - 0.099 11.1 1.5 0.15 10.5 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF687) SRPRB PF09439.10 CDJ62817.1 - 0.17 11.3 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CDJ62817.1 - 1.3 9.3 6.4 9.1 6.6 0.0 3.4 3 1 1 4 4 4 0 AAA domain DDHD PF02862.17 CDJ62817.1 - 6 7.0 8.6 1.2 9.2 0.8 2.7 3 0 0 3 3 3 0 DDHD domain RRM_1 PF00076.22 CDJ62818.1 - 6.2e-23 80.4 0.0 1.1e-07 31.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ62818.1 - 0.072 13.2 0.0 27 5.0 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif Tic110 PF16940.5 CDJ62818.1 - 9.6 4.6 6.7 15 3.9 6.7 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter rve PF00665.26 CDJ62820.1 - 2e-13 50.6 0.0 5.6e-13 49.1 0.0 1.7 1 1 1 2 2 2 1 Integrase core domain SOBP PF15279.6 CDJ62821.1 - 0.17 12.5 28.5 0.19 12.3 28.5 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2828 PF11443.8 CDJ62821.1 - 0.82 7.7 13.4 0.95 7.5 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SPX PF03105.19 CDJ62821.1 - 2.3 8.1 21.1 3.9 7.3 21.1 1.4 1 0 0 1 1 1 0 SPX domain Integrase_H2C2 PF17921.1 CDJ62822.1 - 5.2e-14 52.1 0.3 1.8e-13 50.3 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ62822.1 - 4.3e-13 49.5 0.0 1e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ62822.1 - 0.0061 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF4211 PF13926.6 CDJ62822.1 - 0.049 13.7 0.0 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) Alanine_zipper PF11839.8 CDJ62824.1 - 1.1 9.7 10.9 0.11 12.9 5.8 2.0 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Thioredoxin_8 PF13905.6 CDJ62825.1 - 1.5e-19 70.1 0.0 2.2e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CDJ62825.1 - 1.9e-07 31.5 0.0 3.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CDJ62825.1 - 7.9e-05 22.6 0.0 0.00075 19.4 0.0 2.3 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin PF00085.20 CDJ62825.1 - 0.0008 19.4 0.0 0.015 15.3 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 CDJ62825.1 - 0.019 15.1 0.0 0.063 13.5 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like Kelch_5 PF13854.6 CDJ62826.1 - 8e-11 41.7 0.9 8e-06 25.7 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 CDJ62826.1 - 6.2e-08 32.5 0.4 0.0017 18.3 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ62826.1 - 3.8e-06 27.1 10.3 0.48 10.8 0.0 6.4 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ62826.1 - 0.0011 19.2 0.3 0.33 11.3 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Peptidase_A22B PF04258.13 CDJ62827.1 - 1.1e-70 238.4 6.9 2e-70 237.6 6.9 1.4 1 1 0 1 1 1 1 Signal peptide peptidase TraX PF05857.11 CDJ62827.1 - 2.7 8.0 11.9 10 6.1 6.0 2.9 2 1 1 3 3 3 0 TraX protein MOZ_SAS PF01853.18 CDJ62828.1 - 1.5e-32 112.7 0.0 1e-30 106.7 0.1 2.2 1 1 1 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 CDJ62828.1 - 1.3e-18 66.3 0.2 2.8e-18 65.3 0.2 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDJ62828.1 - 8e-11 41.7 0.0 2.1e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain RVP_2 PF08284.11 CDJ62829.1 - 6e-08 32.5 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ62829.1 - 1.3e-07 32.1 0.0 3.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ62829.1 - 1.4e-07 32.0 0.0 3.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ62829.1 - 0.012 15.9 0.0 0.038 14.3 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF3552 PF12072.8 CDJ62829.1 - 0.054 12.9 0.9 0.079 12.4 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) rve PF00665.26 CDJ62830.1 - 4.1e-14 52.8 0.0 9e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ62830.1 - 8.9e-11 41.5 0.0 1.9e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 CDJ62830.1 - 0.0047 16.5 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arnt_C PF18583.1 CDJ62831.1 - 0.19 11.4 0.0 0.5 10.0 0.0 1.6 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain V-ATPase_G PF03179.15 CDJ62832.1 - 0.0039 17.7 8.6 0.0068 16.9 8.6 1.4 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ABA_GPCR PF12430.8 CDJ62833.1 - 2.6e-33 115.3 9.0 2.6e-33 115.3 9.0 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CDJ62833.1 - 3.3e-17 62.3 1.9 7e-17 61.3 0.0 2.4 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal WD40 PF00400.32 CDJ62834.1 - 5.2e-23 80.9 11.0 6e-07 30.1 0.8 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ62834.1 - 1.2e-13 51.2 0.0 0.0029 17.9 0.0 5.3 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ62834.1 - 0.052 13.4 0.0 24 4.8 0.0 3.7 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDJ62834.1 - 0.072 12.0 0.2 18 4.1 0.0 3.5 3 2 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1722 PF08349.11 CDJ62835.1 - 0.0014 18.9 1.2 0.0036 17.6 0.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1722) Phasin PF05597.11 CDJ62835.1 - 0.0077 16.2 2.1 0.07 13.1 0.2 2.7 2 1 1 3 3 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) dCMP_cyt_deam_1 PF00383.23 CDJ62836.1 - 7.7e-22 77.1 4.1 7.7e-22 77.1 4.1 2.0 3 0 0 3 3 3 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDJ62836.1 - 1.4e-12 47.5 0.2 2.5e-12 46.7 0.2 1.3 1 0 0 1 1 1 1 MafB19-like deaminase CoaE PF01121.20 CDJ62836.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase Cpn60_TCP1 PF00118.24 CDJ62837.1 - 1.4e-18 66.9 0.2 1.8e-18 66.5 0.2 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2722 PF10846.8 CDJ62838.1 - 0.017 14.1 29.6 0.081 11.9 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ62838.1 - 0.21 11.2 42.6 0.28 10.8 9.8 2.2 2 0 0 2 2 2 0 Spt20 family Hydin_ADK PF17213.3 CDJ62838.1 - 0.26 11.6 20.2 1.1 9.5 12.5 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Prothymosin PF03247.14 CDJ62838.1 - 0.47 10.9 9.9 0.64 10.5 2.5 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family EphA2_TM PF14575.6 CDJ62838.1 - 1.1 10.2 9.7 0.32 11.9 1.3 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PRC2_HTH_1 PF18118.1 CDJ62838.1 - 1.3 9.9 5.9 4.5 8.1 0.9 2.3 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain CcmF_C PF16327.5 CDJ62838.1 - 1.4 8.1 6.1 2.5 7.3 6.1 1.3 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal Suf PF05843.14 CDJ62838.1 - 1.9 8.4 23.6 1.8 8.5 10.7 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SpoIIP PF07454.11 CDJ62838.1 - 2.2 7.7 11.8 3.7 6.9 4.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 CDJ62838.1 - 3.1 7.5 7.9 1.8 8.3 1.1 2.1 2 0 0 2 2 2 0 Connexin DUF4569 PF15133.6 CDJ62838.1 - 3.3 7.3 15.5 2.2 8.0 7.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) PA26 PF04636.13 CDJ62838.1 - 3.8 6.3 9.3 2.3 7.0 4.2 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) FAM176 PF14851.6 CDJ62838.1 - 3.8 7.2 7.8 8 6.1 0.9 2.2 2 0 0 2 2 2 0 FAM176 family eIF-3_zeta PF05091.12 CDJ62838.1 - 4.3 6.2 16.9 1.6 7.6 7.8 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ62838.1 - 4.7 7.2 21.1 3.8 7.5 8.0 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4207 PF13904.6 CDJ62838.1 - 5.1 6.7 28.0 1.4 8.5 15.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) DUF4820 PF16091.5 CDJ62838.1 - 5.6 6.3 13.0 5.2 6.4 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) WRNPLPNID PF15017.6 CDJ62838.1 - 5.8 7.9 10.0 6.8 7.6 2.0 2.4 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Band_3_cyto PF07565.13 CDJ62838.1 - 7.3 6.3 11.6 10 5.9 4.4 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4834 PF16118.5 CDJ62838.1 - 9.1 7.3 21.5 6.2 7.9 8.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) eIF-3_zeta PF05091.12 CDJ62839.1 - 0.0028 16.7 17.3 0.0033 16.5 17.3 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.6 CDJ62839.1 - 2.8 6.2 6.0 3.4 5.9 6.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SOG2 PF10428.9 CDJ62839.1 - 3 6.9 39.5 4 6.5 39.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein NPR3 PF03666.13 CDJ62839.1 - 3.6 6.3 25.6 6.7 5.4 25.6 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SelP_N PF04592.14 CDJ62839.1 - 7.4 5.9 19.4 14 5.0 19.4 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Iso_dh PF00180.20 CDJ62841.1 - 1.7e-36 126.1 0.0 3e-36 125.3 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PSII_Pbs27 PF13326.6 CDJ62841.1 - 5.5 7.3 6.4 0.39 11.0 0.3 2.0 2 0 0 2 2 2 0 Photosystem II Pbs27 TFIIA PF03153.13 CDJ62842.1 - 2.4e-06 27.8 69.9 2.6e-05 24.4 45.6 3.2 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ62842.1 - 8.2e-05 21.7 50.6 0.01 14.8 18.7 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ62842.1 - 0.00029 20.5 69.5 0.0054 16.4 25.4 3.3 3 0 0 3 3 3 3 Spt20 family FmiP_Thoc5 PF09766.9 CDJ62842.1 - 0.0025 17.2 3.2 0.0025 17.2 3.2 3.0 3 0 0 3 3 3 1 Fms-interacting protein/Thoc5 BORG_CEP PF14957.6 CDJ62842.1 - 0.8 10.9 12.5 0.49 11.6 0.8 3.1 3 0 0 3 3 3 0 Cdc42 effector ABC2_membrane_2 PF12679.7 CDJ62842.1 - 1 8.6 6.9 1.3 8.3 0.8 3.2 3 0 0 3 3 3 0 ABC-2 family transporter protein CAF1 PF04857.20 CDJ62842.1 - 1.3 8.2 6.0 1.2 8.2 4.1 1.8 2 0 0 2 2 2 0 CAF1 family ribonuclease EPL1 PF10513.9 CDJ62842.1 - 2.7 8.3 24.9 2.4 8.5 8.2 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like Velvet PF11754.8 CDJ62842.1 - 2.8 7.8 18.1 0.65 9.9 3.9 3.1 3 0 0 3 3 3 0 Velvet factor Band_3_cyto PF07565.13 CDJ62842.1 - 3.5 7.3 17.2 1.5 8.6 4.2 3.1 3 0 0 3 3 3 0 Band 3 cytoplasmic domain TCP PF03634.13 CDJ62842.1 - 4.5 7.8 19.4 0.45 11.1 2.6 3.4 3 0 0 3 3 3 0 TCP family transcription factor RLL PF10036.9 CDJ62842.1 - 5 6.9 28.5 1.5 8.6 3.0 3.4 3 0 0 3 3 3 0 RNA transcription, translation and transport factor protein TauE PF01925.19 CDJ62843.1 - 5.9e-11 42.5 9.8 5.9e-11 42.5 9.8 2.5 3 1 0 3 3 3 1 Sulfite exporter TauE/SafE LAP1C PF05609.12 CDJ62843.1 - 0.037 13.1 30.8 0.065 12.3 30.8 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Utp12 PF04003.12 CDJ62844.1 - 2.1e-07 31.2 6.4 5.5e-07 29.9 6.4 1.8 1 0 0 1 1 1 1 Dip2/Utp12 Family Prefoldin PF02996.17 CDJ62845.1 - 3.7e-09 36.5 0.6 3.7e-09 36.5 0.6 3.1 2 2 0 2 2 2 1 Prefoldin subunit FUSC PF04632.12 CDJ62845.1 - 0.19 10.2 2.6 0.2 10.2 2.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family TFIIA PF03153.13 CDJ62845.1 - 1.2 9.1 12.1 1.3 8.9 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 7TMR-HDED PF07697.11 CDJ62845.1 - 2.2 8.3 10.3 3.1 7.9 10.3 1.1 1 0 0 1 1 1 0 7TM-HD extracellular V_ATPase_I PF01496.19 CDJ62846.1 - 0.033 12.1 20.1 0.034 12.1 20.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CobT PF06213.12 CDJ62846.1 - 0.15 11.5 27.9 0.15 11.5 27.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT OATP PF03137.20 CDJ62846.1 - 0.17 10.1 10.1 0.19 10.0 10.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.18 CDJ62846.1 - 0.18 10.5 11.2 0.18 10.5 11.2 1.0 1 0 0 1 1 1 0 Reduced folate carrier FAM176 PF14851.6 CDJ62846.1 - 0.22 11.1 10.2 0.23 11.1 10.2 1.1 1 0 0 1 1 1 0 FAM176 family CLN3 PF02487.17 CDJ62846.1 - 0.27 10.2 14.8 0.26 10.3 14.8 1.0 1 0 0 1 1 1 0 CLN3 protein RPOL_N PF14700.6 CDJ62846.1 - 0.33 10.3 23.3 0.35 10.2 23.3 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF913 PF06025.12 CDJ62846.1 - 0.37 9.7 15.0 0.41 9.6 15.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 CDJ62846.1 - 0.57 10.3 17.2 0.59 10.3 17.2 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SID-1_RNA_chan PF13965.6 CDJ62846.1 - 0.77 8.1 10.2 0.8 8.0 10.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SpoIIP PF07454.11 CDJ62846.1 - 0.94 8.9 23.5 0.95 8.9 23.5 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Ureide_permease PF07168.11 CDJ62846.1 - 0.95 8.1 8.4 0.86 8.3 8.4 1.1 1 0 0 1 1 1 0 Ureide permease Presenilin PF01080.17 CDJ62846.1 - 1 8.0 24.1 1 8.0 24.1 1.0 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 CDJ62846.1 - 1 9.7 16.0 1.1 9.6 16.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TFB6 PF17110.5 CDJ62846.1 - 1.1 9.0 11.7 1.1 9.0 11.7 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DDHD PF02862.17 CDJ62846.1 - 1.3 9.1 19.3 1.3 9.1 19.3 1.0 1 0 0 1 1 1 0 DDHD domain Connexin PF00029.19 CDJ62846.1 - 1.3 8.7 16.9 1.3 8.7 16.9 1.0 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 CDJ62846.1 - 1.3 8.8 20.4 1.3 8.7 20.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2828 PF11443.8 CDJ62846.1 - 1.5 6.8 20.9 1.5 6.8 20.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3408 PF11888.8 CDJ62846.1 - 1.7 8.8 20.5 1.8 8.7 20.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Nucleoside_tran PF01733.18 CDJ62846.1 - 1.9 7.8 9.3 2.1 7.6 9.3 1.0 1 0 0 1 1 1 0 Nucleoside transporter CBP_BcsG PF11658.8 CDJ62846.1 - 1.9 6.8 16.0 1.9 6.8 16.0 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG YABBY PF04690.13 CDJ62846.1 - 2.4 8.7 17.2 2.3 8.8 17.2 1.0 1 0 0 1 1 1 0 YABBY protein Tim54 PF11711.8 CDJ62846.1 - 2.4 6.8 21.9 2.8 6.6 21.9 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FPN1 PF06963.12 CDJ62846.1 - 2.5 6.6 8.7 2.6 6.5 8.7 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Baculo_PP31 PF05311.11 CDJ62846.1 - 2.6 7.5 20.0 2.6 7.5 20.0 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) MMU163 PF17119.5 CDJ62846.1 - 2.9 7.0 10.8 2.9 7.0 10.8 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF4746 PF15928.5 CDJ62846.1 - 3.1 7.2 16.5 3.2 7.1 16.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF5308 PF17233.2 CDJ62846.1 - 3.1 8.0 17.9 3.2 8.0 17.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Ctr PF04145.15 CDJ62846.1 - 3.1 8.4 11.8 3.1 8.4 11.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Peptidase_S49_N PF08496.10 CDJ62846.1 - 3.3 7.8 18.9 3.7 7.6 18.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EIIBC-GUT_N PF03612.14 CDJ62846.1 - 3.7 7.3 18.6 4.4 7.0 18.6 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus MCD PF05292.11 CDJ62846.1 - 3.9 7.0 11.8 4.1 6.9 11.8 1.0 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain Serinc PF03348.15 CDJ62846.1 - 4.5 6.1 14.0 4.3 6.2 14.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) ALMT PF11744.8 CDJ62846.1 - 4.6 6.0 16.7 4.4 6.0 16.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ62846.1 - 5.1 6.0 21.2 5.1 6.0 21.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 EOS1 PF12326.8 CDJ62846.1 - 5.3 6.9 13.1 5.6 6.9 13.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ62846.1 - 5.7 5.8 29.6 5.9 5.8 29.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PPL5 PF18168.1 CDJ62846.1 - 6 6.1 16.4 6.2 6.0 16.4 1.0 1 0 0 1 1 1 0 Prim-pol family 5 CCDC53 PF10152.9 CDJ62846.1 - 6.2 7.2 24.1 6.5 7.2 24.1 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Peroxin-13_N PF04088.13 CDJ62846.1 - 6.5 7.0 13.0 7.4 6.8 13.0 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region PAP2 PF01569.21 CDJ62846.1 - 6.6 6.5 5.9 13 5.5 5.9 1.6 1 1 0 1 1 1 0 PAP2 superfamily Pex14_N PF04695.13 CDJ62846.1 - 6.8 7.3 35.2 7 7.3 35.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CSG2 PF16965.5 CDJ62846.1 - 7.9 5.3 13.8 7.9 5.3 13.8 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Band_3_cyto PF07565.13 CDJ62846.1 - 8.1 6.2 21.0 8.2 6.1 21.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Dynamin_N PF00350.23 CDJ62846.1 - 8.3 6.4 12.9 8.6 6.4 12.9 1.1 1 0 0 1 1 1 0 Dynamin family Neur_chan_memb PF02932.16 CDJ62846.1 - 8.6 6.3 18.0 9.2 6.2 18.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BORG_CEP PF14957.6 CDJ62846.1 - 9.5 7.4 15.6 10 7.3 15.6 1.1 1 0 0 1 1 1 0 Cdc42 effector Peptidase_S15 PF02129.18 CDJ62846.1 - 9.9 5.7 16.9 10 5.6 16.9 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4192 PF13830.6 CDJ62846.1 - 10 6.1 10.1 10 6.1 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF3446 PF11928.8 CDJ62847.1 - 0.018 15.3 14.4 0.018 15.3 14.4 2.3 3 0 0 3 3 3 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ62847.1 - 0.026 14.1 24.1 0.04 13.5 24.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 CDJ62847.1 - 0.34 10.6 7.0 0.48 10.1 7.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Chorion_2 PF03964.15 CDJ62847.1 - 1.4 9.8 21.6 1 10.2 2.2 2.2 2 0 0 2 2 2 0 Chorion family 2 TraG-D_C PF12696.7 CDJ62847.1 - 5.2 7.1 6.5 7.4 6.6 6.5 1.2 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG NTP_transf_4 PF13562.6 CDJ62848.1 - 0.025 14.8 0.3 0.027 14.7 0.3 1.0 1 0 0 1 1 1 0 Sugar nucleotidyl transferase DFP PF04127.15 CDJ62848.1 - 0.031 14.1 5.5 0.036 13.9 5.5 1.1 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein CcmE PF03100.15 CDJ62848.1 - 0.21 11.6 1.5 0.4 10.7 1.5 1.4 1 1 0 1 1 1 0 CcmE Wzz PF02706.15 CDJ62848.1 - 0.53 10.6 6.4 0.67 10.3 6.4 1.1 1 0 0 1 1 1 0 Chain length determinant protein RskA PF10099.9 CDJ62848.1 - 0.55 10.5 21.2 0.75 10.1 21.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA IHABP4_N PF16174.5 CDJ62848.1 - 2.3 8.8 7.7 2.5 8.7 7.7 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal TFIIA PF03153.13 CDJ62848.1 - 3.5 7.5 18.1 3.9 7.4 18.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Adenylsucc_synt PF00709.21 CDJ62849.1 - 1.3e-112 376.8 0.0 2.3e-112 376.0 0.0 1.4 1 1 0 1 1 1 1 Adenylosuccinate synthetase Peptidase_S15 PF02129.18 CDJ62849.1 - 0.33 10.5 3.0 0.55 9.8 3.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Spt20 PF12090.8 CDJ62849.1 - 6.9 6.2 13.5 11 5.5 13.5 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ62849.1 - 9.5 6.1 15.1 0.63 10.0 10.0 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ62850.1 - 0.0019 18.2 4.7 0.0019 18.2 4.7 4.5 3 1 1 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 DUF3446 PF11928.8 CDJ62850.1 - 0.0029 17.9 12.4 0.028 14.7 2.9 2.6 2 0 0 2 2 2 2 Early growth response N-terminal domain HflK_N PF12221.8 CDJ62850.1 - 0.0058 16.6 1.1 0.0058 16.6 1.1 2.8 3 0 0 3 3 3 1 Bacterial membrane protein N terminal LEF-4 PF05098.12 CDJ62850.1 - 0.032 13.0 1.8 0.053 12.3 1.8 1.2 1 0 0 1 1 1 0 Late expression factor 4 (LEF-4) SPX PF03105.19 CDJ62850.1 - 0.068 13.1 7.8 0.12 12.2 7.8 1.4 1 1 0 1 1 1 0 SPX domain OATP PF03137.20 CDJ62850.1 - 0.64 8.2 2.7 2.6 6.2 0.1 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family LCD1 PF09798.9 CDJ62850.1 - 1.1 7.7 7.5 2.7 6.4 7.5 1.5 1 1 0 1 1 1 0 DNA damage checkpoint protein Activator_LAG-3 PF11498.8 CDJ62850.1 - 1.1 8.2 44.0 2.3 7.1 22.7 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF4667 PF15700.5 CDJ62850.1 - 1.5 8.9 10.2 10 6.1 8.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) IMUP PF15761.5 CDJ62850.1 - 2.4 8.9 14.1 0.076 13.7 2.1 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein EIIBC-GUT_N PF03612.14 CDJ62850.1 - 2.8 7.6 7.7 4.7 6.9 0.3 2.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Hydin_ADK PF17213.3 CDJ62850.1 - 2.9 8.1 21.3 34 4.6 17.2 2.7 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain SpoVR PF04293.13 CDJ62850.1 - 3.5 6.2 8.8 2 7.0 0.4 2.1 2 0 0 2 2 2 0 SpoVR like protein Lin-8 PF03353.15 CDJ62850.1 - 3.7 7.0 17.3 1.2 8.6 8.5 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Comm PF15957.5 CDJ62851.1 - 0.54 10.6 4.5 5.8 7.3 1.0 2.5 2 0 0 2 2 2 0 Commissureless MLANA PF14991.6 CDJ62851.1 - 2 8.7 4.8 29 5.0 0.5 2.6 2 0 0 2 2 2 0 Protein melan-A Lactamase_B_6 PF16661.5 CDJ62852.1 - 9.3e-14 51.3 0.0 1.5e-05 24.5 0.0 3.3 2 1 0 3 3 3 3 Metallo-beta-lactamase superfamily domain SPX PF03105.19 CDJ62852.1 - 0.17 11.8 6.8 0.23 11.3 6.8 1.1 1 0 0 1 1 1 0 SPX domain TAF4 PF05236.14 CDJ62852.1 - 0.86 9.3 7.8 0.11 12.2 2.1 2.3 2 1 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Acyl_transf_3 PF01757.22 CDJ62852.1 - 2.1 7.3 11.7 3.7 6.5 11.7 1.3 1 0 0 1 1 1 0 Acyltransferase family DUF4614 PF15391.6 CDJ62852.1 - 5.2 7.0 10.7 11 5.9 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 CDJ62852.1 - 6.6 5.5 5.6 8.6 5.1 5.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SMC_N PF02463.19 CDJ62853.1 - 1.7e-17 63.6 26.9 4.3e-17 62.3 25.7 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain UCH PF00443.29 CDJ62855.1 - 0.0003 20.3 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3446 PF11928.8 CDJ62855.1 - 0.0048 17.2 6.1 0.0048 17.2 6.1 3.7 3 1 0 3 3 3 2 Early growth response N-terminal domain Spt20 PF12090.8 CDJ62856.1 - 0.0032 17.1 19.0 0.036 13.7 7.4 2.1 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ62856.1 - 0.0067 15.4 12.4 0.031 13.2 5.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ62856.1 - 0.025 14.6 33.9 0.41 10.7 10.4 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Activator_LAG-3 PF11498.8 CDJ62856.1 - 0.23 10.4 27.3 0.11 11.4 6.8 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Roughex PF06020.11 CDJ62856.1 - 0.29 10.2 13.5 0.11 11.5 5.8 2.1 2 0 0 2 2 2 0 Drosophila roughex protein PEHE PF15275.6 CDJ62856.1 - 8.1 7.1 10.8 0.95 10.1 1.2 2.2 2 0 0 2 2 2 0 PEHE domain UCH PF00443.29 CDJ62857.1 - 5.5e-30 104.7 0.0 7.6e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TMEM51 PF15345.6 CDJ62857.1 - 0.047 13.5 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 UCH_1 PF13423.6 CDJ62857.1 - 0.091 12.3 0.1 0.41 10.2 0.1 2.0 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Milton PF12448.8 CDJ62857.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinesin associated protein SUIM_assoc PF16619.5 CDJ62858.1 - 5.5e-05 23.1 43.1 0.0099 15.9 7.7 3.4 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 YjeJ PF15922.5 CDJ62858.1 - 0.032 13.4 0.1 0.032 13.4 0.1 2.0 2 0 0 2 2 2 0 YjeJ-like P5-ATPase PF12409.8 CDJ62858.1 - 0.045 13.9 1.0 0.045 13.9 1.0 2.4 3 0 0 3 3 3 0 P5-type ATPase cation transporter DUF5312 PF17239.2 CDJ62858.1 - 0.096 11.0 3.5 0.18 10.1 3.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5312) BRF1 PF07741.13 CDJ62858.1 - 0.56 10.6 8.3 0.14 12.5 1.0 2.8 3 0 0 3 3 3 0 Brf1-like TBP-binding domain RAB3GAP2_N PF14655.6 CDJ62858.1 - 1.1 8.5 14.3 0.22 10.8 2.0 3.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1840 PF08895.11 CDJ62858.1 - 1.7 9.1 12.1 0.17 12.2 2.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) EPL1 PF10513.9 CDJ62858.1 - 2 8.8 8.4 2.1 8.7 0.2 3.0 3 0 0 3 3 3 0 Enhancer of polycomb-like Phostensin_N PF13916.6 CDJ62858.1 - 3.5 8.0 19.7 3.2 8.2 0.2 3.6 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal DUF4834 PF16118.5 CDJ62858.1 - 3.9 8.5 13.7 5.5 8.0 1.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Mlo PF03094.15 CDJ62859.1 - 1.2e-06 27.2 3.3 4.9e-05 21.9 0.5 2.9 1 1 1 3 3 3 1 Mlo family EF-hand_1 PF00036.32 CDJ62859.1 - 5.7e-05 22.4 0.0 0.0095 15.4 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CDJ62859.1 - 0.00025 20.7 0.0 0.019 14.9 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CDJ62859.1 - 0.015 14.8 0.1 0.11 12.0 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 CDJ62859.1 - 0.057 13.9 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair WBP-1 PF11669.8 CDJ62859.1 - 0.9 10.2 6.7 22 5.7 2.4 3.3 3 0 0 3 3 3 0 WW domain-binding protein 1 T3SS_needle_F PF09392.10 CDJ62859.1 - 3.3 8.0 7.5 7.1 6.9 7.5 1.5 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Ribosomal_L16 PF00252.18 CDJ62861.1 - 1.1e-15 57.8 0.1 1.6e-15 57.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e bMG10 PF17973.1 CDJ62863.1 - 5.3 7.3 5.8 23 5.2 1.3 3.7 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain PSII PF00421.19 CDJ62864.1 - 0.34 9.5 1.1 0.42 9.2 1.1 1.1 1 0 0 1 1 1 0 Photosystem II protein DUF2070 PF09843.9 CDJ62864.1 - 3 6.0 7.8 3.9 5.6 7.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-CCCH PF00642.24 CDJ62865.1 - 1.1e-10 41.2 13.7 2.1e-05 24.3 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ62865.1 - 4.7e-05 23.3 15.9 0.011 15.7 5.7 2.6 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 CDJ62865.1 - 5.2e-05 23.9 1.3 0.099 13.4 0.1 2.4 2 0 0 2 2 2 2 Torus domain RRM_1 PF00076.22 CDJ62865.1 - 7.4e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 CDJ62865.1 - 0.06 13.6 2.7 5.9 7.2 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 CDJ62865.1 - 1.5 8.7 16.2 3.2 7.7 6.6 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger RabGAP-TBC PF00566.18 CDJ62866.1 - 3.1e-19 69.5 4.3 5.3e-19 68.7 4.3 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 CDJ62866.1 - 0.018 15.6 0.0 8.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Rhodanese-like domain MAP65_ASE1 PF03999.12 CDJ62867.1 - 0.00018 20.3 0.0 0.00018 20.3 0.0 2.0 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Mon1 PF03164.14 CDJ62868.1 - 1.7e-32 113.0 0.0 2.7e-22 79.4 0.0 2.7 1 1 1 2 2 2 2 Trafficking protein Mon1 CcdA PF07362.12 CDJ62868.1 - 2.2 8.8 6.5 24 5.5 0.0 3.4 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA Brix PF04427.18 CDJ62869.1 - 7.1e-33 114.3 0.0 1e-32 113.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.13 CDJ62869.1 - 0.069 13.1 18.1 0.096 12.7 18.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ62869.1 - 8.9 4.7 12.9 13 4.2 12.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF5336 PF17270.2 CDJ62870.1 - 6.3e-05 22.7 9.2 1.7 8.3 0.1 5.5 6 0 0 6 6 6 4 Family of unknown function (DUF5336) Lipoprotein_1 PF00820.19 CDJ62870.1 - 0.021 13.9 2.7 22 4.0 0.1 3.4 3 0 0 3 3 3 0 Borrelia lipoprotein Tubulin PF00091.25 CDJ62875.1 - 1.1e-65 221.5 0.0 1.8e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ62875.1 - 2.3e-29 102.1 0.0 4.1e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDJ62875.1 - 2.9e-05 24.4 0.0 6.1e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CDJ62875.1 - 0.0038 16.5 0.0 0.0068 15.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin like DUF4667 PF15700.5 CDJ62876.1 - 0.019 15.1 6.8 0.029 14.5 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Vps39_2 PF10367.9 CDJ62876.1 - 0.86 10.1 4.8 0.13 12.7 0.7 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Methyltransf_25 PF13649.6 CDJ62877.1 - 2.4e-13 50.6 0.1 5.1e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ62877.1 - 1.8e-12 47.7 0.0 3.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ62877.1 - 2.3e-11 43.8 0.0 3.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ62877.1 - 4.6e-09 36.9 0.0 1e-08 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ62877.1 - 6e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ62877.1 - 0.00044 20.3 0.1 0.001 19.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 CDJ62877.1 - 0.001 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 CDJ62877.1 - 0.0073 15.9 0.4 0.058 12.9 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 CDJ62877.1 - 0.021 14.1 0.0 0.041 13.2 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.14 CDJ62877.1 - 0.14 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB FHA PF00498.26 CDJ62878.1 - 8.8e-09 35.6 0.0 2.3e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ62878.1 - 1e-05 25.7 0.0 2.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain HBS1_N PF08938.10 CDJ62878.1 - 0.056 13.8 0.8 0.13 12.5 0.8 1.7 1 0 0 1 1 1 0 HBS1 N-terminus DcuC PF03606.15 CDJ62879.1 - 0.11 10.9 0.1 0.18 10.2 0.1 1.3 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier PAT1 PF09770.9 CDJ62879.1 - 4.5 5.4 41.5 5.4 5.1 41.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EF-hand_1 PF00036.32 CDJ62880.1 - 6.1e-33 109.9 14.3 5.2e-09 35.0 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ62880.1 - 5.3e-29 100.5 7.1 5.6e-14 52.4 2.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ62880.1 - 3.3e-27 92.0 7.4 5e-09 35.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDJ62880.1 - 5.1e-21 74.3 10.4 3.8e-13 49.1 0.9 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CDJ62880.1 - 1.7e-14 53.9 0.1 3.9e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ62880.1 - 1.3e-13 49.8 12.7 0.00023 20.5 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 CDJ62880.1 - 7.4e-05 22.7 3.4 0.45 10.5 0.3 3.2 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SurA_N_3 PF13624.6 CDJ62880.1 - 0.00049 19.9 1.1 0.25 11.1 0.1 2.1 1 1 1 2 2 2 2 SurA N-terminal domain Dockerin_1 PF00404.18 CDJ62880.1 - 0.0024 18.0 0.2 0.13 12.4 0.1 2.4 2 1 0 2 2 2 1 Dockerin type I domain DUF853 PF05872.12 CDJ62880.1 - 0.0053 15.4 0.1 0.53 8.8 0.0 2.0 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF853) SurA_N_2 PF13623.6 CDJ62880.1 - 0.0057 16.5 0.1 1.1 9.1 0.1 2.2 2 0 0 2 2 2 1 SurA N-terminal domain Sigma54_CBD PF04963.13 CDJ62880.1 - 0.027 14.3 0.1 0.036 13.9 0.1 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain SPARC_Ca_bdg PF10591.9 CDJ62880.1 - 0.031 14.6 0.0 6.6 7.1 0.1 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Staphylokinase PF02821.16 CDJ62880.1 - 0.041 14.3 0.3 0.19 12.2 0.2 2.1 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family EF-hand_14 PF17959.1 CDJ62880.1 - 0.047 14.0 0.4 3 8.2 0.1 2.6 1 1 2 3 3 3 0 EF-hand domain DUF3349 PF11829.8 CDJ62880.1 - 0.09 13.6 1.6 4.7 8.0 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) Acetyltransf_11 PF13720.6 CDJ62880.1 - 0.12 12.8 0.1 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Phage_TAC_12 PF12363.8 CDJ62880.1 - 0.15 12.5 1.8 0.53 10.7 0.3 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC HTH_40 PF14493.6 CDJ62880.1 - 0.26 11.8 2.0 4.9 7.7 0.2 2.3 1 1 0 2 2 2 0 Helix-turn-helix domain MgtE_N PF03448.17 CDJ62880.1 - 0.66 10.6 3.5 0.43 11.2 0.3 2.2 3 0 0 3 3 3 0 MgtE intracellular N domain SHOCT PF09851.9 CDJ62880.1 - 1 9.2 0.1 1 9.2 0.1 3.5 4 0 0 4 4 4 0 Short C-terminal domain DAGK_acc PF00609.19 CDJ62881.1 - 2.2e-30 106.1 0.0 8.5e-15 55.4 0.0 2.8 2 1 1 3 3 3 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CDJ62881.1 - 8.9e-22 77.0 0.0 1.3e-14 53.9 0.0 2.6 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 CDJ62881.1 - 7.7e-11 41.7 26.9 2.9e-08 33.5 2.1 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pinin_SDK_memA PF04696.13 CDJ62882.1 - 1.4e-18 67.2 12.0 1.4e-18 67.2 12.0 1.6 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region SOGA PF11365.8 CDJ62882.1 - 0.12 13.5 8.2 22 6.2 1.7 3.4 2 1 1 3 3 3 0 Protein SOGA zf-CCHC_3 PF13917.6 CDJ62883.1 - 0.028 14.4 0.5 0.028 14.4 0.5 2.4 1 1 1 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CDJ62883.1 - 0.23 11.8 7.1 0.62 10.5 7.1 1.6 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC PF00098.23 CDJ62883.1 - 0.32 11.2 9.9 1.6 9.0 2.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ62883.1 - 2 8.3 7.6 5 7.0 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 CDJ62884.1 - 2.5e-21 76.2 0.0 3.9e-21 75.6 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hema_stalk PF08720.10 CDJ62889.1 - 0.15 11.8 0.3 0.33 10.6 0.3 1.5 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk XTBD PF11952.8 CDJ62891.1 - 0.084 12.6 0.2 0.79 9.5 0.2 1.9 1 1 0 1 1 1 0 XRN-Two Binding Domain, XTBD Sybindin PF04099.12 CDJ62892.1 - 1.1e-28 99.9 0.0 2.3e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Sybindin-like family Sec16_C PF12931.7 CDJ62892.1 - 1.2e-16 61.2 5.6 1.2e-16 61.2 5.6 3.5 3 2 0 3 3 3 1 Sec23-binding domain of Sec16 Sedlin_N PF04628.13 CDJ62892.1 - 3e-05 24.1 0.0 8e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region SpoIIP PF07454.11 CDJ62893.1 - 9.3 5.6 12.3 13 5.2 7.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) GAS PF13851.6 CDJ62894.1 - 0.0076 15.6 15.9 0.011 15.1 12.9 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Spc29 PF17082.5 CDJ62894.1 - 0.048 13.5 0.6 0.048 13.5 0.6 1.8 1 1 1 2 2 2 0 Spindle Pole Component 29 Prominin PF05478.11 CDJ62894.1 - 0.22 9.4 4.6 0.33 8.8 4.6 1.2 1 0 0 1 1 1 0 Prominin GCD14 PF08704.10 CDJ62894.1 - 0.24 11.0 4.1 0.37 10.4 4.1 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit ALMT PF11744.8 CDJ62894.1 - 0.54 9.0 6.1 0.68 8.7 6.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DAG_kinase_N PF14513.6 CDJ62894.1 - 0.67 10.1 7.9 0.24 11.6 5.3 1.5 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF1682 PF07946.14 CDJ62894.1 - 1.1 8.4 14.4 0.055 12.7 7.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Herpes_UL6 PF01763.16 CDJ62894.1 - 1.7 7.1 9.0 1.3 7.5 8.1 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like Seryl_tRNA_N PF02403.22 CDJ62894.1 - 2.9 8.2 12.0 0.75 10.0 7.0 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4600 PF15372.6 CDJ62894.1 - 3.1 8.3 14.1 6.6 7.2 13.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Sas6_CC PF18594.1 CDJ62894.1 - 3.7 7.4 14.4 0.11 12.3 3.2 2.5 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain TMEM192 PF14802.6 CDJ62894.1 - 8.2 5.4 7.6 15 4.6 1.5 2.3 2 0 0 2 2 2 0 TMEM192 family DUF1930 PF09122.10 CDJ62895.1 - 0.0055 16.7 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) Pol_alpha_B_N PF08418.10 CDJ62895.1 - 0.16 11.9 12.9 0.26 11.2 12.9 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal BUD22 PF09073.10 CDJ62895.1 - 0.47 9.7 27.1 0.55 9.5 27.1 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 CDJ62895.1 - 1.5 8.5 17.9 2.5 7.8 17.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PNISR PF15996.5 CDJ62895.1 - 2.5 8.3 20.0 5.6 7.2 20.0 1.6 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR U3_assoc_6 PF08640.11 CDJ62896.1 - 7.7e-10 38.7 2.8 7.7e-10 38.7 2.8 2.6 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 DUF755 PF05501.11 CDJ62896.1 - 3.2e-05 24.2 30.8 0.00013 22.2 12.4 15.0 13 2 1 14 14 14 3 Domain of unknown function (DUF755) TPR_14 PF13428.6 CDJ62896.1 - 9.2e-05 23.0 3.5 9.2e-05 23.0 3.5 8.7 8 2 2 10 10 10 3 Tetratricopeptide repeat Spt20 PF12090.8 CDJ62896.1 - 0.0022 17.7 9.3 0.0022 17.7 9.3 7.1 4 2 2 7 7 7 1 Spt20 family TPR_2 PF07719.17 CDJ62896.1 - 1 9.6 12.8 0.59 10.4 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RskA PF10099.9 CDJ62897.1 - 0.03 14.6 5.1 0.051 13.9 5.1 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4636 PF15468.6 CDJ62897.1 - 0.044 13.5 0.4 0.066 12.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) F-box-like PF12937.7 CDJ62898.1 - 0.0051 16.7 3.8 0.0051 16.7 3.8 1.8 2 0 0 2 2 2 1 F-box-like V_ATPase_I PF01496.19 CDJ62898.1 - 0.82 7.5 8.9 1.2 7.0 8.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA PF00004.29 CDJ62899.1 - 2.7e-14 53.7 0.0 2.7e-14 53.7 0.0 3.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF4667 PF15700.5 CDJ62899.1 - 0.0015 18.7 3.0 0.0015 18.7 3.0 7.9 5 3 1 6 6 6 2 Domain of unknown function (DUF4667) AAA_33 PF13671.6 CDJ62899.1 - 0.13 12.4 0.0 0.13 12.4 0.0 3.9 4 1 0 4 4 4 0 AAA domain AAA_17 PF13207.6 CDJ62899.1 - 0.15 12.5 0.0 0.15 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CDJ62899.1 - 0.59 10.6 14.1 0.076 13.5 4.2 2.7 2 1 0 2 2 2 0 AAA domain MecA PF05389.12 CDJ62899.1 - 0.97 9.0 11.0 0.059 13.0 2.4 3.0 4 0 0 4 4 4 0 Negative regulator of genetic competence (MecA) EB1 PF03271.17 CDJ62900.1 - 6.7e-12 45.5 0.0 1.7e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CDJ62900.1 - 0.0012 19.0 0.4 0.0019 18.4 0.4 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF4407 PF14362.6 CDJ62900.1 - 0.22 10.8 5.6 0.28 10.5 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Suf PF05843.14 CDJ62900.1 - 0.28 11.1 2.6 0.34 10.8 2.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SUIM_assoc PF16619.5 CDJ62900.1 - 0.63 10.2 17.8 0.23 11.6 1.5 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ62900.1 - 0.67 9.9 14.0 0.89 9.5 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ62900.1 - 0.89 10.2 11.4 1.4 9.5 11.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region STIMATE PF12400.8 CDJ62901.1 - 8.8e-06 26.3 0.0 1.4e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 STIMATE family DUF4207 PF13904.6 CDJ62901.1 - 0.12 12.0 0.2 0.12 12.0 0.2 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) FAM104 PF15434.6 CDJ62901.1 - 4.5 7.9 8.6 17 6.0 2.5 2.4 2 0 0 2 2 2 0 Family 104 Surface_antigen PF11054.8 CDJ62902.1 - 5.8e-34 117.9 1.3 8.6e-34 117.3 1.3 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62903.1 - 7.1e-35 120.8 0.3 9.7e-35 120.4 0.3 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62904.1 - 8.9e-28 97.6 0.1 7.7e-27 94.5 0.1 2.0 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ62905.1 - 2.1e-24 86.6 1.4 4.9e-24 85.4 1.4 1.5 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen FYRC PF05965.14 CDJ62905.1 - 0.0081 16.3 0.0 5.8 7.2 0.0 2.3 2 0 0 2 2 2 2 F/Y rich C-terminus Surface_antigen PF11054.8 CDJ62906.1 - 3e-34 118.8 1.6 4.9e-34 118.1 1.6 1.3 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Peripla_BP_5 PF13433.6 CDJ62906.1 - 0.1 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain LEH PF07858.12 CDJ62906.1 - 0.13 12.4 0.1 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 Limonene-1,2-epoxide hydrolase catalytic domain Surface_antigen PF11054.8 CDJ62907.1 - 1.7e-34 119.6 1.5 2.1e-34 119.3 1.5 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Chromo PF00385.24 CDJ62908.1 - 1e-14 54.1 0.0 1.2e-13 50.7 0.0 2.5 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 CDJ62908.1 - 0.0011 19.1 0.1 0.0038 17.5 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF3425 PF11905.8 CDJ62908.1 - 0.04 13.9 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) Metal_resist PF13801.6 CDJ62910.1 - 0.00046 20.4 0.9 0.00046 20.4 0.9 1.7 2 0 0 2 2 2 1 Heavy-metal resistance IF-2 PF11987.8 CDJ62911.1 - 8.5e-21 74.1 0.9 1.1e-20 73.7 0.9 1.2 1 0 0 1 1 1 1 Translation-initiation factor 2 RNA_helicase PF00910.22 CDJ62914.1 - 0.00047 20.5 1.2 0.00091 19.6 0.0 2.1 2 1 0 2 2 2 1 RNA helicase EOS1 PF12326.8 CDJ62914.1 - 0.0067 16.4 2.5 0.0067 16.4 2.5 3.3 4 1 0 4 4 4 1 N-glycosylation protein MMR_HSR1 PF01926.23 CDJ62914.1 - 0.028 14.5 1.3 0.07 13.2 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase SID-1_RNA_chan PF13965.6 CDJ62914.1 - 5.3 5.3 11.9 0.31 9.4 2.0 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Vitellogenin_N PF01347.22 CDJ62915.1 - 0.013 13.9 0.4 0.016 13.7 0.4 1.0 1 0 0 1 1 1 0 Lipoprotein amino terminal region SR-25 PF10500.9 CDJ62915.1 - 0.35 10.4 20.3 0.37 10.4 17.9 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF677 PF05055.12 CDJ62915.1 - 4.9 5.9 8.9 7.6 5.3 8.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF677) Trp_oprn_chp PF09534.10 CDJ62915.1 - 6.2 6.6 28.6 9.2 6.0 28.6 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TFIIA PF03153.13 CDJ62915.1 - 7.2 6.5 9.8 8.5 6.3 9.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4404 PF14357.6 CDJ62916.1 - 0.075 13.7 9.6 3 8.5 9.4 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) AMP-binding PF00501.28 CDJ62917.1 - 3.6e-06 25.8 2.3 6.5e-05 21.7 1.0 3.7 3 1 0 3 3 3 2 AMP-binding enzyme GRDP-like PF07173.12 CDJ62917.1 - 0.051 14.2 0.1 0.051 14.2 0.1 2.9 2 1 0 2 2 2 0 Glycine-rich domain-containing protein-like SUIM_assoc PF16619.5 CDJ62918.1 - 1.6e-06 28.1 1.2 8.7e-05 22.5 1.4 14.4 10 4 1 11 11 11 4 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ62918.1 - 0.0014 19.0 5.4 0.0014 19.0 5.4 20.9 5 5 9 14 14 14 2 Anti-sigma-K factor rskA SPX PF03105.19 CDJ62918.1 - 0.0016 18.5 16.3 0.0016 18.5 16.3 7.6 5 2 0 5 5 5 1 SPX domain eIF3_p135 PF12807.7 CDJ62920.1 - 6.9e-15 55.5 0.0 6.9e-15 55.5 0.0 4.8 5 1 0 5 5 5 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.6 CDJ62920.1 - 7.5e-07 29.2 3.0 5.5e-06 26.4 0.1 3.2 2 1 0 2 2 2 1 Clustered mitochondria RVT_1 PF00078.27 CDJ62921.1 - 1.8e-14 53.8 0.0 3.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CDJ62921.1 - 5.2e-11 42.4 0.0 9.4e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ62921.1 - 3.3e-10 40.4 0.0 8.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ62921.1 - 1.5e-09 38.3 0.0 3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 CDJ62921.1 - 8.8e-06 25.9 0.0 2.6e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 CDJ62921.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ62921.1 - 0.0029 17.9 0.0 0.011 16.0 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease DUF3552 PF12072.8 CDJ62921.1 - 0.013 15.0 1.0 0.02 14.3 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PNK3P PF08645.11 CDJ62924.1 - 0.016 14.9 0.3 0.032 13.9 0.3 1.5 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase DUF1110 PF06533.12 CDJ62924.1 - 0.04 13.9 0.1 0.066 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) DUF2608 PF11019.8 CDJ62924.1 - 0.085 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) HAD_2 PF13419.6 CDJ62924.1 - 0.81 9.7 6.0 10 6.2 0.1 2.7 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase MOLO1 PF17175.4 CDJ62925.1 - 1.7e-06 28.2 0.2 3.8e-06 27.0 0.2 1.6 1 1 0 1 1 1 1 Modulator of levamisole receptor-1 SSB PF00436.25 CDJ62927.1 - 1.2e-32 112.0 0.1 1.7e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family RNA_Me_trans PF04252.13 CDJ62928.1 - 2.1e-48 164.6 0.0 2.7e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase CPW_WPC PF09717.10 CDJ62929.1 - 0.00019 22.4 0.0 0.022 15.8 0.2 2.2 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) Glycos_trans_3N PF02885.17 CDJ62929.1 - 0.21 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Presenilin PF01080.17 CDJ62930.1 - 0.019 13.8 30.9 0.022 13.5 30.9 1.1 1 0 0 1 1 1 0 Presenilin Endostatin PF06482.11 CDJ62930.1 - 0.054 13.0 27.5 0.074 12.5 27.5 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4045 PF13254.6 CDJ62930.1 - 0.15 11.7 23.2 0.18 11.4 23.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Zip PF02535.22 CDJ62930.1 - 0.15 11.2 29.0 0.19 10.9 29.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Lin-8 PF03353.15 CDJ62930.1 - 0.17 11.5 30.3 0.19 11.3 30.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ62930.1 - 0.19 10.3 25.6 0.23 9.9 25.6 1.1 1 0 0 1 1 1 0 Macoilin family PAT1 PF09770.9 CDJ62930.1 - 0.23 9.7 54.0 0.26 9.5 54.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ62930.1 - 0.59 7.2 31.7 0.69 7.0 31.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 CDJ62930.1 - 0.68 8.9 27.7 0.77 8.8 27.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2052 PF09747.9 CDJ62930.1 - 0.71 10.0 24.9 1 9.4 24.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Bud13 PF09736.9 CDJ62930.1 - 0.73 10.2 27.1 1 9.8 27.1 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex RR_TM4-6 PF06459.12 CDJ62930.1 - 0.73 9.6 30.7 0.94 9.3 30.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ62930.1 - 0.83 7.9 24.7 0.97 7.6 24.7 1.0 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ62930.1 - 0.91 8.5 31.8 1.1 8.1 31.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 CDJ62930.1 - 0.99 9.4 23.1 1.2 9.0 23.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A NPR3 PF03666.13 CDJ62930.1 - 1 8.1 26.6 1.2 7.9 26.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AbLIM_anchor PF16182.5 CDJ62930.1 - 1.1 9.0 22.9 1.3 8.8 22.9 1.0 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM CAC1F_C PF16885.5 CDJ62930.1 - 1.2 8.8 20.8 1.4 8.5 20.8 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term NARP1 PF12569.8 CDJ62930.1 - 1.3 7.8 26.9 1.6 7.5 26.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ALMT PF11744.8 CDJ62930.1 - 1.7 7.4 24.4 2 7.2 24.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Bul1_N PF04425.12 CDJ62930.1 - 1.8 7.2 23.3 2.2 6.9 23.3 1.2 1 0 0 1 1 1 0 Bul1 N terminus AF-4 PF05110.13 CDJ62930.1 - 1.9 6.5 41.2 2.1 6.3 41.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SRP-alpha_N PF04086.13 CDJ62930.1 - 2.4 8.0 24.7 2.9 7.7 24.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDK5_activator PF03261.15 CDJ62930.1 - 3 7.3 29.1 3.5 7.1 29.1 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SID-1_RNA_chan PF13965.6 CDJ62930.1 - 3.1 6.1 12.2 4.9 5.5 12.2 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3292 PF11696.8 CDJ62930.1 - 3.5 5.9 17.2 4.9 5.4 17.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Hid1 PF12722.7 CDJ62930.1 - 3.7 5.5 30.2 4.3 5.3 30.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HCO3_cotransp PF00955.21 CDJ62930.1 - 4 6.1 14.0 4.9 5.9 14.0 1.1 1 0 0 1 1 1 0 HCO3- transporter family Tim54 PF11711.8 CDJ62930.1 - 4.1 6.1 22.3 6.1 5.5 22.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Caldesmon PF02029.15 CDJ62930.1 - 5.2 5.7 28.8 6.5 5.4 28.8 1.2 1 0 0 1 1 1 0 Caldesmon Sin_N PF04801.13 CDJ62930.1 - 5.4 6.1 43.4 6.2 5.9 43.4 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region DUF4746 PF15928.5 CDJ62930.1 - 5.8 6.3 19.2 8.6 5.7 19.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Neur_chan_memb PF02932.16 CDJ62930.1 - 6.9 6.7 27.1 11 6.0 27.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Membralin PF09746.9 CDJ62930.1 - 7.1 5.6 21.1 8.7 5.3 21.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein Peptidase_S64 PF08192.11 CDJ62930.1 - 8.5 4.7 25.2 10 4.5 25.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 GPCR_chapero_1 PF11904.8 CDJ62930.1 - 9 5.6 19.5 11 5.3 19.5 1.2 1 0 0 1 1 1 0 GPCR-chaperone TAF4 PF05236.14 CDJ62931.1 - 2.7 7.7 8.7 3.7 7.2 0.1 2.5 2 1 1 3 3 3 0 Transcription initiation factor TFIID component TAF4 family DUF3138 PF11336.8 CDJ62931.1 - 3.6 6.1 5.5 5.6 5.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PCNA_N PF00705.18 CDJ62932.1 - 8.4e-23 80.5 0.1 2.2e-22 79.1 0.1 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain TFIIA PF03153.13 CDJ62932.1 - 0.0012 18.9 43.0 0.0018 18.3 43.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 CDJ62932.1 - 0.038 13.9 15.3 0.056 13.4 15.3 1.2 1 0 0 1 1 1 0 Velvet factor Glyco_trans_2_3 PF13632.6 CDJ62932.1 - 0.061 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 SLC12 PF03522.15 CDJ62932.1 - 0.064 12.3 15.4 0.083 11.9 15.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Exonuc_VII_L PF02601.15 CDJ62932.1 - 0.099 12.2 22.3 0.13 11.8 22.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DDHD PF02862.17 CDJ62932.1 - 0.22 11.7 9.2 0.34 11.0 9.2 1.3 1 0 0 1 1 1 0 DDHD domain Caldesmon PF02029.15 CDJ62932.1 - 0.27 9.9 15.9 0.34 9.6 15.9 1.1 1 0 0 1 1 1 0 Caldesmon Ureide_permease PF07168.11 CDJ62932.1 - 0.4 9.4 0.0 0.4 9.4 0.0 2.7 2 1 0 2 2 1 0 Ureide permease ALMT PF11744.8 CDJ62932.1 - 0.79 8.5 12.8 1.2 7.9 12.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Band_3_cyto PF07565.13 CDJ62932.1 - 0.88 9.3 15.5 1.5 8.6 15.5 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MAJIN PF15077.6 CDJ62932.1 - 0.89 9.3 8.6 1.4 8.6 8.6 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein eIF-3_zeta PF05091.12 CDJ62932.1 - 1.6 7.6 20.8 2.5 7.0 20.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FapA PF03961.13 CDJ62932.1 - 2.5 6.6 11.5 3.4 6.2 11.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HemX PF04375.14 CDJ62932.1 - 3.1 7.0 45.0 4.9 6.3 45.0 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase PAT1 PF09770.9 CDJ62932.1 - 3.2 5.9 39.5 4.2 5.5 39.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MMR1 PF08505.10 CDJ62932.1 - 4.3 7.6 20.7 7.4 6.8 20.7 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF3450 PF11932.8 CDJ62932.1 - 5.3 6.3 38.6 11 5.3 38.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Suf PF05843.14 CDJ62932.1 - 5.5 6.9 23.3 9.4 6.1 23.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BORG_CEP PF14957.6 CDJ62932.1 - 6 8.0 16.0 11 7.2 16.0 1.3 1 0 0 1 1 1 0 Cdc42 effector Fer4_18 PF13746.6 CDJ62933.1 - 0.1 12.8 0.6 0.31 11.2 0.6 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain RskA PF10099.9 CDJ62934.1 - 2.3 8.5 61.1 0.026 14.8 21.8 4.2 1 1 3 4 4 4 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ62935.1 - 5.2 7.0 25.8 6.5 6.6 25.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 CDJ62937.1 - 8.7 5.7 20.5 10 5.4 20.5 1.1 1 0 0 1 1 1 0 SDA1 Glyco_hydro_35 PF01301.19 CDJ62938.1 - 2.7e-09 37.1 0.2 2.7e-07 30.5 0.0 3.7 3 0 0 3 3 3 1 Glycosyl hydrolases family 35 DUF1645 PF07816.11 CDJ62938.1 - 0.0019 18.8 10.9 0.0019 18.8 10.9 9.8 6 3 3 9 9 9 2 Protein of unknown function (DUF1645) Sin_N PF04801.13 CDJ62938.1 - 0.0036 16.6 0.4 0.0036 16.6 0.4 7.0 4 3 0 5 5 5 1 Sin-like protein conserved region Spc7 PF08317.11 CDJ62939.1 - 0.00074 18.5 10.5 0.00096 18.1 10.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Tup_N PF08581.10 CDJ62939.1 - 0.015 15.6 6.3 0.027 14.7 6.3 1.4 1 0 0 1 1 1 0 Tup N-terminal Serine_protease PF18405.1 CDJ62939.1 - 0.19 10.9 0.1 0.35 10.0 0.1 1.4 1 0 0 1 1 1 0 Gammaproteobacterial serine protease UPF0242 PF06785.11 CDJ62939.1 - 0.79 9.8 8.0 1 9.4 8.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GHMP_kinases_N PF00288.26 CDJ62939.1 - 1.4 9.2 10.6 0.34 11.2 0.8 2.7 2 0 0 2 2 2 0 GHMP kinases N terminal domain TMPIT PF07851.13 CDJ62939.1 - 2.1 7.5 4.5 2.9 7.1 4.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein HEAT PF02985.22 CDJ62940.1 - 0.004 17.3 4.2 0.075 13.3 0.1 4.5 4 0 0 4 4 4 1 HEAT repeat DUF1645 PF07816.11 CDJ62940.1 - 0.026 15.1 0.1 0.026 15.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) IMUP PF15761.5 CDJ62940.1 - 0.047 14.4 8.5 0.047 14.4 8.5 2.9 3 0 0 3 3 3 0 Immortalisation up-regulated protein LpxC PF03331.13 CDJ62940.1 - 0.06 12.8 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase MMS19_C PF12460.8 CDJ62940.1 - 0.065 12.3 0.9 0.18 10.9 0.1 2.0 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Arm PF00514.23 CDJ62940.1 - 0.14 12.2 2.5 0.52 10.4 0.2 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CDJ62940.1 - 0.75 10.4 0.1 0.75 10.4 0.1 4.3 3 1 1 4 4 4 0 HEAT-like repeat PUB PF09409.10 CDJ62941.1 - 7e-12 45.1 0.0 1.7e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 PUB domain MDM1 PF15501.6 CDJ62941.1 - 5.4e-06 25.8 30.9 0.00013 21.3 5.9 2.2 2 0 0 2 2 2 2 Nuclear protein MDM1 DUF4746 PF15928.5 CDJ62941.1 - 0.0063 16.0 12.8 0.0063 16.0 12.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4746) Dapper PF15268.6 CDJ62941.1 - 0.017 14.0 32.6 0.035 13.0 18.1 2.1 2 0 0 2 2 2 0 Dapper CAF1 PF04857.20 CDJ62941.1 - 0.3 10.2 11.8 1.9 7.6 8.2 2.3 2 0 0 2 2 2 0 CAF1 family ribonuclease CNDH2_C PF16858.5 CDJ62941.1 - 0.65 9.8 33.6 0.22 11.4 16.2 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term AAA_11 PF13086.6 CDJ62941.1 - 0.71 9.6 30.3 0.073 12.8 15.5 2.2 2 0 0 2 2 2 0 AAA domain DUF572 PF04502.13 CDJ62941.1 - 4.5 6.8 33.4 0.43 10.1 14.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Hamartin PF04388.12 CDJ62941.1 - 5.8 5.5 31.3 0.61 8.7 14.4 2.2 2 0 0 2 2 2 0 Hamartin protein RRP7 PF12923.7 CDJ62942.1 - 8.5e-12 45.3 11.6 3.8e-11 43.2 11.6 2.0 1 1 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF5093 PF17011.5 CDJ62942.1 - 9e-05 22.8 1.5 9.9e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5093) RRM_7 PF16367.5 CDJ62942.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 CDJ62942.1 - 0.092 12.6 0.0 0.41 10.5 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CDJ62942.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain DUF2011 PF09428.10 CDJ62942.1 - 0.18 12.1 1.1 1.3 9.3 0.6 2.4 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) DUF1005 PF06219.12 CDJ62942.1 - 0.36 9.8 3.7 0.6 9.1 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) Ribosomal_S6e PF01092.19 CDJ62945.1 - 3.1e-52 175.8 0.0 5.8e-52 174.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Baculo_p24 PF05073.12 CDJ62946.1 - 0.76 9.5 2.1 1.4 8.7 2.1 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein CCDC53 PF10152.9 CDJ62946.1 - 6.3 7.2 6.5 1.4 9.3 1.6 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Scramblase PF03803.15 CDJ62948.1 - 0.23 10.7 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Scramblase Symplekin_C PF12295.8 CDJ62950.1 - 6.3e-39 134.0 0.2 7.8e-39 133.7 0.2 1.1 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal WD40 PF00400.32 CDJ62951.1 - 9.6e-07 29.4 6.7 0.0084 16.9 0.0 5.0 4 1 0 4 4 4 2 WD domain, G-beta repeat SecIII_SopE_N PF05364.14 CDJ62951.1 - 0.061 13.4 0.9 0.22 11.6 0.1 2.1 2 0 0 2 2 2 0 Salmonella type III secretion SopE effector N-terminus RVT_1 PF00078.27 CDJ62952.1 - 2e-08 34.0 0.0 4.2e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SBDS PF01172.18 CDJ62953.1 - 2.3e-25 88.5 0.0 4.8e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 CDJ62953.1 - 7.2e-19 67.9 1.2 1.7e-18 66.7 0.0 2.2 2 0 0 2 2 2 1 SBDS protein C-terminal domain GDI PF00996.18 CDJ62954.1 - 7.1e-206 683.8 0.0 8.1e-206 683.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 CDJ62954.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ62954.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain rve PF00665.26 CDJ62955.1 - 4.7e-11 42.9 0.0 6.7e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ62955.1 - 0.11 12.3 1.4 0.11 12.2 0.2 1.7 2 0 0 2 2 2 0 Integrase core domain RskA PF10099.9 CDJ62958.1 - 0.0021 18.4 9.6 0.0021 18.4 9.6 2.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ62958.1 - 0.0071 16.0 15.4 0.0087 15.7 15.4 1.2 1 0 0 1 1 1 1 Spt20 family SUIM_assoc PF16619.5 CDJ62958.1 - 0.014 15.4 15.4 0.014 15.4 15.4 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Hamartin PF04388.12 CDJ62958.1 - 0.29 9.8 10.7 0.34 9.5 10.7 1.0 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 CDJ62958.1 - 0.52 10.3 24.9 0.65 9.9 24.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ62958.1 - 6.5 5.7 9.7 7.1 5.5 9.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ62958.1 - 9.6 6.2 8.3 11 6.0 8.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L13 PF00572.18 CDJ62959.1 - 1.2e-10 41.7 0.1 6.8e-09 36.0 0.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 CAMSAP_CC1 PF17095.5 CDJ62959.1 - 0.38 10.6 4.7 5.9 6.8 2.2 2.5 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin Rrn6 PF10214.9 CDJ62961.1 - 1.3e-06 27.2 0.1 1.3e-06 27.2 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor UPF0542 PF15086.6 CDJ62961.1 - 0.019 14.9 1.0 0.019 14.9 1.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 RskA PF10099.9 CDJ62961.1 - 5.7 7.2 31.7 14 5.9 5.2 3.2 2 1 0 2 2 2 0 Anti-sigma-K factor rskA RF-1 PF00472.20 CDJ62962.1 - 6e-19 68.1 0.5 6e-19 68.1 0.5 3.6 3 1 1 4 4 4 2 RF-1 domain PCRF PF03462.18 CDJ62962.1 - 2.5e-10 40.5 5.4 9.5e-09 35.4 5.4 2.9 1 1 0 1 1 1 1 PCRF domain TFIIA PF03153.13 CDJ62962.1 - 0.082 12.9 8.5 0.12 12.3 8.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PACT_coil_coil PF10495.9 CDJ62962.1 - 6 7.5 9.2 3 8.5 0.1 2.6 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF2339 PF10101.9 CDJ62963.1 - 0.00076 18.2 17.0 0.00076 18.2 17.0 2.2 2 0 0 2 2 2 2 Predicted membrane protein (DUF2339) TFIIA PF03153.13 CDJ62963.1 - 0.017 15.2 7.7 0.017 15.2 7.7 3.6 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 CDJ62963.1 - 0.083 11.2 9.9 0.14 10.4 9.9 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ62964.1 - 0.0029 17.3 9.1 0.0029 17.3 9.1 2.6 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Pap_E4 PF02711.14 CDJ62964.1 - 0.064 14.2 0.1 0.064 14.2 0.1 3.4 5 0 0 5 5 5 0 E4 protein Spore_coat_CotO PF14153.6 CDJ62966.1 - 4.8 7.1 4.8 8.1 6.3 4.8 1.4 1 0 0 1 1 1 0 Spore coat protein CotO RVP_2 PF08284.11 CDJ62968.1 - 3.8e-09 36.4 0.0 1.2e-08 34.8 0.0 1.8 3 0 0 3 3 3 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ62968.1 - 7e-09 36.2 0.0 1.3e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ62968.1 - 8.1e-09 35.9 0.0 1.5e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ62968.1 - 0.0036 17.1 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ62968.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease CagY_M PF07337.11 CDJ62968.1 - 0.097 12.3 0.0 25 4.6 0.0 2.7 2 0 0 2 2 2 0 DC-EC Repeat rve PF00665.26 CDJ62969.1 - 3.6e-11 43.3 0.0 5.7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ62969.1 - 0.32 10.8 1.6 0.36 10.6 0.2 1.8 2 0 0 2 2 2 0 Integrase core domain SpoIIP PF07454.11 CDJ62971.1 - 0.097 12.1 16.8 0.1 12.0 16.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF755 PF05501.11 CDJ62971.1 - 0.16 12.3 28.9 0.2 11.9 28.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ribosomal_60s PF00428.19 CDJ62971.1 - 0.22 12.2 13.1 0.33 11.5 13.1 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Zwint PF15556.6 CDJ62971.1 - 0.61 9.5 36.0 0.67 9.4 36.0 1.1 1 0 0 1 1 1 0 ZW10 interactor PIG-S PF10510.9 CDJ62971.1 - 0.82 8.4 20.2 0.9 8.3 20.2 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Lin-8 PF03353.15 CDJ62971.1 - 0.85 9.1 24.8 0.93 9.0 24.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ62971.1 - 0.95 7.9 18.1 1.1 7.7 18.1 1.1 1 0 0 1 1 1 0 Macoilin family ABC2_membrane_2 PF12679.7 CDJ62971.1 - 1.3 8.3 5.3 1.5 8.1 5.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Mem_trans PF03547.18 CDJ62971.1 - 1.5 7.1 8.3 1.7 7.0 8.3 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4638 PF15472.6 CDJ62971.1 - 1.8 8.3 12.0 1.8 8.2 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Sin_N PF04801.13 CDJ62971.1 - 1.8 7.7 29.2 1.9 7.6 29.2 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Peptidase_S64 PF08192.11 CDJ62971.1 - 2.3 6.6 18.3 2.5 6.5 18.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF572 PF04502.13 CDJ62971.1 - 5.1 6.6 16.6 5.8 6.4 16.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rox3 PF08633.10 CDJ62971.1 - 5.3 7.3 17.4 5.9 7.1 17.4 1.0 1 0 0 1 1 1 0 Rox3 mediator complex subunit GREB1 PF15782.5 CDJ62971.1 - 5.7 3.9 24.2 6.1 3.8 24.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4175 PF13779.6 CDJ62971.1 - 6.2 4.6 38.7 7.2 4.4 38.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ribonuc_P_40 PF08584.11 CDJ62971.1 - 7 5.8 13.8 8 5.7 13.8 1.0 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit EPL1 PF10513.9 CDJ62971.1 - 7 7.0 20.5 9 6.7 20.5 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Sec62 PF03839.16 CDJ62971.1 - 7.2 6.0 11.3 7.3 6.0 11.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DDRGK PF09756.9 CDJ62971.1 - 7.6 6.1 22.7 8.4 5.9 22.7 1.1 1 0 0 1 1 1 0 DDRGK domain V_ATPase_I PF01496.19 CDJ62971.1 - 8.4 4.2 16.2 8 4.2 16.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Miga PF10265.9 CDJ62971.1 - 8.6 5.2 16.6 9.1 5.1 16.6 1.0 1 0 0 1 1 1 0 Mitoguardin EIIBC-GUT_N PF03612.14 CDJ62971.1 - 8.6 6.1 12.5 12 5.6 12.5 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ALMT PF11744.8 CDJ62971.1 - 9.3 4.9 18.7 9.1 5.0 18.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter NAD_binding_1 PF00175.21 CDJ62972.1 - 3.3e-07 30.9 2.8 3.3e-07 30.9 2.8 3.6 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain Isy1 PF06246.12 CDJ62972.1 - 8.8e-05 22.2 5.5 0.0068 16.0 0.3 2.2 2 0 0 2 2 2 2 Isy1-like splicing family RskA PF10099.9 CDJ62972.1 - 0.00018 21.9 26.1 0.00073 19.9 13.9 2.5 3 0 0 3 3 2 2 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ62972.1 - 0.00023 20.3 26.0 0.0011 18.0 7.3 2.5 3 0 0 3 3 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ62972.1 - 0.00052 19.7 46.3 0.002 17.8 9.0 3.1 3 0 0 3 3 3 2 Spt20 family CPSF100_C PF13299.6 CDJ62972.1 - 0.00077 19.7 2.1 0.57 10.4 0.0 2.3 2 0 0 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal PIP5K PF01504.18 CDJ62972.1 - 0.0012 18.1 1.5 0.0025 17.1 1.5 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF1645 PF07816.11 CDJ62972.1 - 0.002 18.8 4.2 0.017 15.7 0.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1645) RAB3GAP2_N PF14655.6 CDJ62972.1 - 0.0034 16.7 11.4 0.021 14.1 2.8 2.4 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Zn_peptidase PF04228.13 CDJ62972.1 - 0.0034 16.9 7.9 0.06 12.8 0.7 2.4 2 0 0 2 2 2 2 Putative neutral zinc metallopeptidase MscS_TM PF12794.7 CDJ62972.1 - 0.0086 15.0 7.4 0.12 11.2 1.2 2.4 2 0 0 2 2 2 2 Mechanosensitive ion channel inner membrane domain 1 Trp_oprn_chp PF09534.10 CDJ62972.1 - 0.0092 15.8 10.8 2.9 7.7 0.0 2.3 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Mgr1 PF08602.10 CDJ62972.1 - 0.011 14.6 6.7 0.078 11.8 6.7 2.0 1 1 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit MTBP_C PF14920.6 CDJ62972.1 - 0.015 15.0 4.2 0.015 15.0 4.2 2.8 3 0 0 3 3 3 0 MDM2-binding Glt_symporter PF03616.14 CDJ62972.1 - 0.028 13.1 2.1 1.2 7.8 0.5 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter Suf PF05843.14 CDJ62972.1 - 0.032 14.2 17.0 0.71 9.8 6.8 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) V_ATPase_I PF01496.19 CDJ62972.1 - 0.048 11.6 5.4 0.29 9.0 1.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NAD_binding_6 PF08030.12 CDJ62972.1 - 0.053 13.6 5.7 0.18 11.9 0.4 2.7 2 1 0 2 2 2 0 Ferric reductase NAD binding domain Thg1C PF14413.6 CDJ62972.1 - 0.076 13.2 8.4 0.64 10.2 1.3 2.6 3 0 0 3 3 2 0 Thg1 C terminal domain Peroxin-13_N PF04088.13 CDJ62972.1 - 0.086 13.1 3.0 2.3 8.5 0.5 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Rpp20 PF12328.8 CDJ62972.1 - 0.094 12.7 11.8 0.42 10.6 0.1 2.6 3 0 0 3 3 2 0 Rpp20 subunit of nuclear RNase MRP and P Dala_Dala_lig_N PF01820.21 CDJ62972.1 - 0.1 13.1 0.3 12 6.5 0.1 2.5 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus DUF3276 PF11680.8 CDJ62972.1 - 0.11 12.6 8.6 8.3 6.6 4.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3276) XRN_N PF03159.18 CDJ62972.1 - 0.13 11.6 4.3 0.6 9.5 0.1 2.3 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus Tsg PF04668.12 CDJ62972.1 - 0.14 12.9 13.0 0.57 10.9 4.8 2.5 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region BP28CT PF08146.12 CDJ62972.1 - 0.3 10.9 5.0 0.3 10.9 0.7 2.3 2 0 0 2 2 2 0 BP28CT (NUC211) domain DUF4179 PF13786.6 CDJ62972.1 - 0.31 11.5 1.7 0.9 10.1 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) eIF_4EBP PF05456.11 CDJ62972.1 - 0.37 10.7 7.0 4.2 7.3 1.6 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) MDM31_MDM32 PF08118.11 CDJ62972.1 - 0.4 9.3 7.3 0.18 10.5 1.5 2.1 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins eIF-3_zeta PF05091.12 CDJ62972.1 - 0.56 9.1 13.7 1.2 8.0 3.5 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ62972.1 - 0.76 8.5 13.3 0.88 8.3 12.7 1.5 1 1 0 1 1 1 0 Presenilin U1snRNP70_N PF12220.8 CDJ62972.1 - 0.8 10.4 11.4 2.4 8.8 0.4 2.9 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RcpC PF16976.5 CDJ62972.1 - 0.86 9.7 11.5 6.5 6.8 0.3 2.6 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB DUF4770 PF15994.5 CDJ62972.1 - 0.87 9.8 13.7 1.1 9.5 2.2 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4770) Rrp15p PF07890.12 CDJ62972.1 - 0.9 9.9 17.4 0.55 10.6 4.4 2.9 3 0 0 3 3 3 0 Rrp15p IMUP PF15761.5 CDJ62972.1 - 0.96 10.2 10.0 3.4 8.4 10.0 1.9 1 0 0 1 1 1 0 Immortalisation up-regulated protein Sec16 PF12932.7 CDJ62972.1 - 1.1 9.8 5.8 1 10.0 0.7 2.6 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region CNDH2_N PF06278.11 CDJ62972.1 - 1.2 9.4 15.3 0.83 9.9 1.8 3.0 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF2391 PF09622.10 CDJ62972.1 - 1.3 8.3 6.2 9.5 5.5 1.7 2.3 2 0 0 2 2 2 0 Putative integral membrane protein (DUF2391) Peptidase_S49_N PF08496.10 CDJ62972.1 - 1.3 9.1 13.7 0.16 12.0 0.3 2.6 3 0 0 3 3 2 0 Peptidase family S49 N-terminal Tau95_N PF17682.1 CDJ62972.1 - 1.4 9.1 8.5 4.3 7.5 1.4 2.6 3 0 0 3 3 2 0 Tau95 Triple barrel domain CagX PF03524.15 CDJ62972.1 - 1.5 8.5 7.5 5.1 6.8 1.3 2.3 2 0 0 2 2 2 0 Conjugal transfer protein STAC2_u1 PF16664.5 CDJ62972.1 - 1.6 9.2 12.6 5.4 7.5 0.7 3.3 3 0 0 3 3 3 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 PMC2NT PF08066.12 CDJ62972.1 - 1.7 9.4 4.7 0.5 11.1 0.6 2.2 2 0 0 2 2 1 0 PMC2NT (NUC016) domain CIAPIN1 PF05093.13 CDJ62972.1 - 2.2 8.9 9.6 19 5.8 4.2 2.6 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis tRNA_synt_1c_R2 PF04557.15 CDJ62972.1 - 2.3 9.2 8.1 13 6.8 2.1 2.7 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 EIIBC-GUT_N PF03612.14 CDJ62972.1 - 2.3 7.9 11.3 3.5 7.3 3.2 2.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Jiraiya PF15038.6 CDJ62972.1 - 2.4 7.5 6.7 0.86 9.0 1.7 2.3 2 0 0 2 2 2 0 Jiraiya JUPITER PF17054.5 CDJ62972.1 - 2.5 7.5 5.4 1 8.8 1.8 1.9 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter DUF2407 PF10302.9 CDJ62972.1 - 3.1 8.4 8.2 9.9 6.8 0.4 2.5 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Baculo_PP31 PF05311.11 CDJ62972.1 - 4.5 6.7 9.5 12 5.3 0.5 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Orf78 PF06024.12 CDJ62972.1 - 5.8 7.3 9.6 7.1 7.0 2.7 2.4 2 0 0 2 2 2 0 Orf78 (ac78) DUF3381 PF11861.8 CDJ62972.1 - 9.5 6.0 20.0 1.9 8.2 2.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) RskA PF10099.9 CDJ62973.1 - 0.016 15.5 32.3 0.021 15.1 32.3 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ62973.1 - 1.4 8.9 9.2 1.5 8.8 9.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4131 PF13567.6 CDJ62973.1 - 7 6.3 6.0 9.8 5.8 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TipE PF16972.5 CDJ62973.1 - 7.7 5.6 11.4 8.1 5.5 11.4 1.0 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE DnaJ-X PF14308.6 CDJ62974.1 - 9.1e-44 149.4 8.9 9.5e-37 126.5 2.6 2.3 2 0 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.31 CDJ62974.1 - 6.6e-19 67.8 0.2 1.5e-18 66.6 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain SR-25 PF10500.9 CDJ62974.1 - 0.013 15.1 13.1 0.013 15.1 13.1 2.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ62974.1 - 7.8 6.9 18.4 0.52 10.6 10.6 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Chorismate_synt PF01264.21 CDJ62975.1 - 1.8e-60 204.4 0.2 8.8e-60 202.1 0.0 2.2 1 1 1 2 2 2 1 Chorismate synthase Spt20 PF12090.8 CDJ62975.1 - 0.0019 17.9 16.9 0.0019 17.9 16.9 3.5 2 1 0 2 2 2 1 Spt20 family FYDLN_acid PF09538.10 CDJ62975.1 - 0.05 14.3 0.3 0.05 14.3 0.3 4.2 3 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Presenilin PF01080.17 CDJ62975.1 - 0.09 11.5 44.8 0.14 10.9 0.1 2.1 2 0 0 2 2 2 0 Presenilin DUF2052 PF09747.9 CDJ62975.1 - 0.11 12.7 44.4 0.64 10.1 31.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Gti1_Pac2 PF09729.9 CDJ62975.1 - 0.97 9.5 30.7 4.6 7.3 1.1 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family FAM60A PF15396.6 CDJ62975.1 - 5.6 6.9 32.7 13 5.7 25.3 2.3 2 0 0 2 2 2 0 Protein Family FAM60A TCP PF03634.13 CDJ62975.1 - 6 7.4 36.7 2 9.0 0.7 2.7 2 0 0 2 2 2 0 TCP family transcription factor Myc_N PF01056.18 CDJ62976.1 - 6 6.7 12.2 7.6 6.3 12.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region SR-25 PF10500.9 CDJ62977.1 - 0.011 15.4 12.4 0.011 15.3 12.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ62977.1 - 0.05 13.9 11.9 0.057 13.7 11.9 1.1 1 0 0 1 1 1 0 Early growth response N-terminal domain NYD-SP28_assoc PF14775.6 CDJ62977.1 - 0.073 13.2 1.2 0.087 12.9 1.2 1.1 1 0 0 1 1 1 0 Sperm tail C-terminal domain Herpes_pp85 PF04637.12 CDJ62977.1 - 0.093 11.1 4.0 0.098 11.1 4.0 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) IMUP PF15761.5 CDJ62977.1 - 0.23 12.2 8.3 0.27 11.9 8.3 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein Chorion_2 PF03964.15 CDJ62977.1 - 1.3 9.9 7.0 1.3 9.9 7.0 1.1 1 0 0 1 1 1 0 Chorion family 2 PAM2 PF07145.15 CDJ62978.1 - 0.00023 20.6 1.0 0.00023 20.6 1.0 2.1 2 0 0 2 2 2 1 Ataxin-2 C-terminal region RskA PF10099.9 CDJ62978.1 - 0.48 10.7 0.0 0.09 13.1 25.8 8.9 3 3 4 7 7 7 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ62979.1 - 2.5e-05 24.0 32.2 2.5e-05 24.0 32.2 2.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ62979.1 - 0.0015 18.8 27.3 0.0021 18.3 27.3 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated DUF3446 PF11928.8 CDJ62979.1 - 0.017 15.4 11.9 0.026 14.8 11.9 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain SDA1 PF05285.12 CDJ62979.1 - 0.09 12.2 38.1 0.16 11.4 38.1 1.4 1 0 0 1 1 1 0 SDA1 Chorion_2 PF03964.15 CDJ62979.1 - 0.13 13.1 6.4 0.29 12.0 6.4 1.6 1 0 0 1 1 1 0 Chorion family 2 DUF936 PF06075.12 CDJ62979.1 - 0.94 8.3 28.4 1.1 8.1 28.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) PPP4R2 PF09184.11 CDJ62979.1 - 1 8.9 38.1 1.2 8.6 38.1 1.1 1 0 0 1 1 1 0 PPP4R2 Myc_N PF01056.18 CDJ62979.1 - 3.9 7.3 22.1 4.8 7.0 22.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF966 PF06136.13 CDJ62979.1 - 5.2 6.7 25.9 6.4 6.4 25.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CAC1F_C PF16885.5 CDJ62979.1 - 5.4 6.6 20.6 6.3 6.4 20.6 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term SR-25 PF10500.9 CDJ62980.1 - 3.1e-06 27.0 61.9 0.00072 19.2 12.2 3.6 3 1 0 3 3 3 3 Nuclear RNA-splicing-associated protein DUF2635 PF10948.8 CDJ62980.1 - 0.48 10.2 2.8 14 5.5 2.8 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2635) Filament_head PF04732.14 CDJ62980.1 - 9.3 7.2 48.8 14 6.6 5.2 3.6 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region Ank_2 PF12796.7 CDJ62981.1 - 2.1e-07 31.4 7.6 2.1e-06 28.2 0.4 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ62981.1 - 2.2e-06 28.1 1.8 6.8e-05 23.3 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ62981.1 - 3.4e-06 27.2 1.5 0.0028 17.9 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ62981.1 - 6.3e-06 26.1 2.3 0.15 12.7 0.1 4.8 4 0 0 4 4 4 2 Ankyrin repeat RLL PF10036.9 CDJ62981.1 - 0.034 14.0 0.5 0.065 13.1 0.5 1.4 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein DUF3446 PF11928.8 CDJ62981.1 - 4.5 7.6 18.6 2.1 8.7 10.8 3.0 3 0 0 3 3 3 0 Early growth response N-terminal domain RL10P_insert PF17777.1 CDJ62982.1 - 1.2e-26 92.5 0.0 1.9e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CDJ62982.1 - 6.5e-12 45.5 0.9 1e-11 44.8 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_L30_N PF08079.12 CDJ62982.1 - 0.14 12.4 2.5 0.36 11.1 2.5 1.7 1 1 0 1 1 1 0 Ribosomal L30 N-terminal domain SR-25 PF10500.9 CDJ62985.1 - 2.1e-07 30.8 15.5 2.1e-07 30.8 15.5 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ62985.1 - 0.00079 19.5 11.9 0.001 19.1 11.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 CDJ62986.1 - 0.032 14.5 16.1 0.037 14.3 16.1 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SPX PF03105.19 CDJ62986.1 - 0.033 14.1 8.8 0.032 14.1 8.8 1.2 1 0 0 1 1 1 0 SPX domain LCD1 PF09798.9 CDJ62986.1 - 0.13 10.8 8.9 0.15 10.6 8.9 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein FAM60A PF15396.6 CDJ62986.1 - 0.14 12.1 8.9 0.16 12.0 8.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CIAPIN1 PF05093.13 CDJ62986.1 - 0.17 12.4 7.1 0.46 11.0 7.1 1.7 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Apt1 PF10351.9 CDJ62986.1 - 0.23 10.3 9.8 0.22 10.3 9.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4207 PF13904.6 CDJ62986.1 - 0.25 11.0 22.8 0.35 10.5 22.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) TERB2 PF15101.6 CDJ62986.1 - 0.35 10.9 17.7 0.53 10.3 17.7 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 AF-4 PF05110.13 CDJ62986.1 - 0.37 8.8 22.2 0.41 8.7 22.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4647 PF15504.6 CDJ62986.1 - 0.39 9.8 15.4 0.47 9.5 15.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Lin-8 PF03353.15 CDJ62986.1 - 0.42 10.1 20.9 0.52 9.8 20.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NST1 PF13945.6 CDJ62986.1 - 0.46 10.6 22.7 0.79 9.8 22.7 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF755 PF05501.11 CDJ62986.1 - 0.55 10.5 30.7 0.8 10.0 30.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Peptidase_S64 PF08192.11 CDJ62986.1 - 0.76 8.2 15.8 0.81 8.1 15.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF1635 PF07795.11 CDJ62986.1 - 0.9 9.4 19.1 1.3 8.8 19.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) ALMT PF11744.8 CDJ62986.1 - 1.2 7.8 13.0 1.4 7.7 13.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SR-25 PF10500.9 CDJ62986.1 - 1.7 8.2 27.1 2.6 7.6 27.1 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ62986.1 - 2.1 7.9 38.3 3.1 7.4 38.3 1.2 1 0 0 1 1 1 0 Spt20 family Sec62 PF03839.16 CDJ62986.1 - 2.8 7.4 9.0 3.4 7.1 9.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Membralin PF09746.9 CDJ62986.1 - 2.8 6.9 8.1 3.2 6.7 8.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein SLC12 PF03522.15 CDJ62986.1 - 3.1 6.7 15.1 3.6 6.5 15.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Miga PF10265.9 CDJ62986.1 - 3.6 6.4 18.7 4 6.3 18.7 1.1 1 0 0 1 1 1 0 Mitoguardin NPR3 PF03666.13 CDJ62986.1 - 7.4 5.2 13.7 8.6 5.0 13.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MPM1 PF17234.2 CDJ62986.1 - 8.6 6.6 16.9 12 6.1 16.9 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 SOG2 PF10428.9 CDJ62986.1 - 9.5 5.3 34.5 12 5.0 34.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4834 PF16118.5 CDJ62987.1 - 1.1e-06 29.5 9.6 0.00087 20.2 0.7 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4834) EcsB PF05975.12 CDJ62987.1 - 0.00012 21.1 6.4 0.00016 20.7 6.4 1.2 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB YfhO PF09586.10 CDJ62987.1 - 0.0026 16.1 2.3 0.0026 16.1 2.3 2.1 1 1 1 2 2 2 2 Bacterial membrane protein YfhO NnrS PF05940.12 CDJ62987.1 - 0.0073 15.7 12.2 0.0092 15.4 12.2 1.2 1 0 0 1 1 1 1 NnrS protein Peptidase_S49_N PF08496.10 CDJ62987.1 - 0.018 15.1 8.2 1.9 8.5 0.0 3.0 3 0 0 3 3 3 0 Peptidase family S49 N-terminal TMEM18 PF14770.6 CDJ62987.1 - 0.019 15.0 9.9 0.26 11.3 9.9 2.4 1 1 0 1 1 1 0 Transmembrane protein 18 TMEM208_SND2 PF05620.11 CDJ62987.1 - 0.021 14.6 3.1 0.021 14.6 3.1 3.2 2 1 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 GPR15L PF15854.5 CDJ62987.1 - 0.028 14.7 3.1 2.3 8.5 0.1 2.5 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 DUF2393 PF09624.10 CDJ62987.1 - 0.051 13.6 0.8 0.14 12.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Oxidored_q3 PF00499.20 CDJ62987.1 - 0.069 12.9 5.3 0.028 14.1 2.5 1.8 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF3377 PF11857.8 CDJ62987.1 - 0.11 12.5 5.2 1.6 8.7 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF3899 PF13038.6 CDJ62987.1 - 0.12 12.8 2.0 19 5.8 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) OATP PF03137.20 CDJ62987.1 - 0.13 10.5 0.7 0.43 8.8 0.6 1.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3464 PF11947.8 CDJ62987.1 - 0.14 11.9 4.7 51 3.6 5.6 2.9 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 RskA PF10099.9 CDJ62987.1 - 0.15 12.4 25.1 0.13 12.6 9.8 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA SID-1_RNA_chan PF13965.6 CDJ62987.1 - 0.16 10.3 0.4 0.33 9.3 0.2 1.7 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1178 PF06676.11 CDJ62987.1 - 0.19 12.1 17.1 0.59 10.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) Connexin PF00029.19 CDJ62987.1 - 0.25 11.1 1.8 1.4 8.6 1.9 2.0 2 1 0 2 2 2 0 Connexin Orf78 PF06024.12 CDJ62987.1 - 0.34 11.2 11.8 7.1 7.0 0.0 3.2 2 1 1 3 3 3 0 Orf78 (ac78) XK-related PF09815.9 CDJ62987.1 - 0.46 9.5 7.4 0.24 10.4 5.4 1.5 1 1 0 1 1 1 0 XK-related protein ATP-synt_I PF03899.15 CDJ62987.1 - 0.9 9.9 10.4 0.28 11.6 6.2 2.2 2 1 0 2 2 2 0 ATP synthase I chain FA_desaturase PF00487.24 CDJ62987.1 - 0.94 9.3 7.9 3.1 7.5 5.7 2.0 1 1 1 2 2 2 0 Fatty acid desaturase SRTM1 PF15872.5 CDJ62987.1 - 1.2 9.3 8.9 0.99 9.6 0.4 2.3 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 DUF1980 PF09323.10 CDJ62987.1 - 1.9 8.3 8.5 0.88 9.5 4.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) Trp_oprn_chp PF09534.10 CDJ62987.1 - 3.9 7.2 19.6 0.34 10.7 8.6 2.6 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Macoilin PF09726.9 CDJ62988.1 - 0.28 9.7 32.1 0.34 9.4 32.1 1.1 1 0 0 1 1 1 0 Macoilin family PPP4R2 PF09184.11 CDJ62988.1 - 1.6 8.3 16.0 1.9 8.0 16.0 1.2 1 0 0 1 1 1 0 PPP4R2 SPX PF03105.19 CDJ62988.1 - 7.8 6.3 26.3 11 5.8 26.3 1.3 1 0 0 1 1 1 0 SPX domain Pyr_redox_2 PF07992.14 CDJ62989.1 - 4.3e-41 141.1 5.4 2.4e-39 135.3 5.4 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ62989.1 - 7.4e-17 61.7 0.9 1.6e-14 54.2 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ62989.1 - 1e-08 34.8 1.1 0.00043 19.6 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDJ62989.1 - 4.9e-05 22.6 2.4 0.0013 18.0 1.4 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Velvet PF11754.8 CDJ62989.1 - 0.00013 22.0 10.6 0.00019 21.5 10.6 1.2 1 0 0 1 1 1 1 Velvet factor TFIIA PF03153.13 CDJ62989.1 - 0.00015 21.9 16.0 0.00024 21.2 16.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ62989.1 - 0.00045 18.9 8.7 0.00057 18.6 8.7 1.1 1 0 0 1 1 1 1 Macoilin family HI0933_like PF03486.14 CDJ62989.1 - 0.0012 17.7 2.7 0.025 13.3 0.2 2.3 2 0 0 2 2 2 1 HI0933-like protein Suf PF05843.14 CDJ62989.1 - 0.0018 18.3 11.4 0.0032 17.5 11.4 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Apt1 PF10351.9 CDJ62989.1 - 0.0019 17.2 13.7 0.0026 16.7 13.7 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain DUF572 PF04502.13 CDJ62989.1 - 0.0021 17.7 8.2 0.0021 17.7 8.2 1.5 2 0 0 2 2 1 1 Family of unknown function (DUF572) FAD_oxidored PF12831.7 CDJ62989.1 - 0.0077 15.6 1.1 0.0077 15.6 1.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CDJ62989.1 - 0.011 15.0 3.8 0.052 12.8 0.0 2.7 3 0 0 3 3 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 CDJ62989.1 - 0.013 14.7 0.9 0.031 13.3 0.9 1.6 1 0 0 1 1 1 0 FAD binding domain MRP-S26 PF14943.6 CDJ62989.1 - 0.013 15.5 6.2 0.022 14.7 6.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 ASD2 PF08687.11 CDJ62989.1 - 0.019 14.5 11.2 0.032 13.8 11.2 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Zip PF02535.22 CDJ62989.1 - 0.02 14.1 2.7 0.026 13.7 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.12 CDJ62989.1 - 0.022 13.8 8.1 0.028 13.4 8.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GIDA PF01134.22 CDJ62989.1 - 0.023 13.8 0.0 0.023 13.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A CAC1F_C PF16885.5 CDJ62989.1 - 0.031 13.9 9.0 0.047 13.4 9.0 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Neur_chan_memb PF02932.16 CDJ62989.1 - 0.046 13.8 7.2 0.078 13.0 7.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Coilin_N PF15862.5 CDJ62989.1 - 0.049 13.4 16.0 0.13 12.1 16.0 1.7 1 0 0 1 1 1 0 Coilin N-terminus Rtf2 PF04641.12 CDJ62989.1 - 0.057 12.8 9.0 0.097 12.0 9.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger MAP70 PF07058.11 CDJ62989.1 - 0.061 12.1 10.9 0.081 11.7 10.9 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 DUF4614 PF15391.6 CDJ62989.1 - 0.088 12.8 28.1 0.15 12.0 28.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Presenilin PF01080.17 CDJ62989.1 - 0.098 11.4 18.1 0.15 10.8 18.1 1.2 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ62989.1 - 0.11 13.1 21.5 0.036 14.7 17.8 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dicty_REP PF05086.12 CDJ62989.1 - 0.18 9.8 6.4 0.23 9.4 6.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hid1 PF12722.7 CDJ62989.1 - 0.19 9.8 14.7 0.25 9.4 14.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2828 PF11443.8 CDJ62989.1 - 0.19 9.7 8.9 0.29 9.1 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Sec3_C PF09763.9 CDJ62989.1 - 0.22 9.9 11.9 0.37 9.1 11.9 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec3 Med3 PF11593.8 CDJ62989.1 - 0.26 10.4 13.1 0.51 9.5 13.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4407 PF14362.6 CDJ62989.1 - 0.31 10.4 5.0 0.47 9.7 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF913 PF06025.12 CDJ62989.1 - 0.31 10.0 7.1 0.48 9.3 7.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PI3K_1B_p101 PF10486.9 CDJ62989.1 - 0.34 8.6 13.3 0.45 8.2 13.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NPR3 PF03666.13 CDJ62989.1 - 0.46 9.2 20.2 0.74 8.5 20.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RSRP PF17069.5 CDJ62989.1 - 0.46 10.0 38.2 0.81 9.2 38.2 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 SOBP PF15279.6 CDJ62989.1 - 0.48 11.0 18.0 0.16 12.6 15.2 1.5 2 0 0 2 2 1 0 Sine oculis-binding protein Spt20 PF12090.8 CDJ62989.1 - 0.61 9.7 30.7 1.2 8.8 30.7 1.4 1 0 0 1 1 1 0 Spt20 family THRAP3_BCLAF1 PF15440.6 CDJ62989.1 - 0.72 8.8 39.1 1 8.3 39.1 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family GREB1 PF15782.5 CDJ62989.1 - 0.77 6.8 15.6 0.98 6.5 15.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spore_coat_CotO PF14153.6 CDJ62989.1 - 0.83 9.6 14.1 0.14 12.1 10.0 1.7 2 0 0 2 2 2 0 Spore coat protein CotO PA26 PF04636.13 CDJ62989.1 - 0.84 8.5 9.3 1.2 7.9 9.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM199X PF15814.5 CDJ62989.1 - 0.94 8.5 28.0 1.5 7.8 28.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X SID-1_RNA_chan PF13965.6 CDJ62989.1 - 1 7.7 4.2 1.4 7.2 4.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MAJIN PF15077.6 CDJ62989.1 - 1.1 9.0 14.5 1.9 8.2 14.5 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein Connexin PF00029.19 CDJ62989.1 - 1.1 9.0 6.5 1.8 8.2 6.5 1.3 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 CDJ62989.1 - 1.3 7.9 6.4 1.7 7.4 6.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Dsh_C PF12316.8 CDJ62989.1 - 1.5 9.2 24.6 2.4 8.5 24.6 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SLC12 PF03522.15 CDJ62989.1 - 1.5 7.8 13.7 2.5 7.0 13.7 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 CDJ62989.1 - 1.5 7.2 14.8 2.2 6.7 14.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_S49_N PF08496.10 CDJ62989.1 - 2.7 8.0 10.2 8.1 6.5 7.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3464 PF11947.8 CDJ62989.1 - 2.9 7.6 11.8 6.6 6.5 11.8 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Androgen_recep PF02166.16 CDJ62989.1 - 3 6.6 18.6 4.8 5.9 18.6 1.3 1 0 0 1 1 1 0 Androgen receptor CPSF100_C PF13299.6 CDJ62989.1 - 4.1 7.6 11.3 3.2 7.9 6.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF5521 PF17659.1 CDJ62989.1 - 5 4.8 9.0 7 4.4 9.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) NAD_binding_8 PF13450.6 CDJ62989.1 - 5.4 7.3 8.3 3.5 7.9 2.5 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Band_3_cyto PF07565.13 CDJ62989.1 - 5.9 6.6 12.7 11 5.8 12.7 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SSP160 PF06933.11 CDJ62989.1 - 6.5 4.8 14.8 8.9 4.4 14.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 V_ATPase_I PF01496.19 CDJ62989.1 - 6.7 4.5 11.9 9.7 4.0 11.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Period_C PF12114.8 CDJ62989.1 - 7.4 6.1 29.1 12 5.4 29.1 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Pyr_redox_dim PF02852.22 CDJ62990.1 - 2.8e-13 50.1 0.0 4.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain MAGE_N PF12440.8 CDJ62990.1 - 0.0004 21.0 19.2 0.00064 20.3 19.2 1.2 1 0 0 1 1 1 1 Melanoma associated antigen family N terminal TFIIA PF03153.13 CDJ62990.1 - 0.0036 17.4 10.6 0.0042 17.2 10.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ62990.1 - 0.005 16.5 15.3 0.0071 16.0 15.3 1.2 1 0 0 1 1 1 1 Spt20 family CDK2AP PF09806.9 CDJ62990.1 - 0.0058 16.7 10.5 0.0071 16.4 10.5 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Lin-8 PF03353.15 CDJ62990.1 - 0.0069 16.0 6.6 0.0081 15.8 6.6 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist AF-4 PF05110.13 CDJ62990.1 - 0.013 13.6 23.4 0.017 13.2 23.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Apt1 PF10351.9 CDJ62990.1 - 0.014 14.2 8.0 0.015 14.2 8.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Slu7 PF11708.8 CDJ62990.1 - 0.019 14.7 3.3 0.024 14.4 3.3 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor SPX PF03105.19 CDJ62990.1 - 0.024 14.6 7.0 0.026 14.5 7.0 1.1 1 0 0 1 1 1 0 SPX domain MAP65_ASE1 PF03999.12 CDJ62990.1 - 0.025 13.3 6.9 0.028 13.1 6.9 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Secretin_N_2 PF07655.13 CDJ62990.1 - 0.037 14.6 8.1 0.037 14.6 8.1 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Peptidase_S64 PF08192.11 CDJ62990.1 - 0.054 12.0 8.6 0.06 11.8 8.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Miga PF10265.9 CDJ62990.1 - 0.065 12.2 6.7 0.075 12.0 6.7 1.0 1 0 0 1 1 1 0 Mitoguardin DUF1635 PF07795.11 CDJ62990.1 - 0.074 12.9 9.7 0.11 12.4 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) PNISR PF15996.5 CDJ62990.1 - 0.1 12.9 7.5 0.13 12.6 7.5 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Macoilin PF09726.9 CDJ62990.1 - 0.1 11.1 12.7 0.13 10.8 12.7 1.0 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CDJ62990.1 - 0.16 10.7 7.3 0.19 10.4 7.3 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ62990.1 - 0.16 10.6 7.8 0.18 10.4 7.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peroxin-3 PF04882.12 CDJ62990.1 - 0.17 10.9 11.9 0.19 10.7 11.9 1.0 1 0 0 1 1 1 0 Peroxin-3 RAP1 PF07218.11 CDJ62990.1 - 0.3 9.3 6.0 0.31 9.3 6.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MPM1 PF17234.2 CDJ62990.1 - 0.36 11.1 8.5 0.57 10.4 8.5 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF4050 PF13259.6 CDJ62990.1 - 0.36 11.1 7.2 0.48 10.7 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Roughex PF06020.11 CDJ62990.1 - 0.5 9.4 7.0 0.62 9.1 7.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Gti1_Pac2 PF09729.9 CDJ62990.1 - 0.5 10.4 6.9 0.67 10.0 6.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family GREB1 PF15782.5 CDJ62990.1 - 0.55 7.3 12.1 0.68 7.0 12.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 CDJ62990.1 - 0.57 8.9 3.4 0.67 8.7 3.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Clr2 PF10383.9 CDJ62990.1 - 0.59 10.9 3.9 1.1 10.0 3.8 1.4 1 1 0 1 1 1 0 Transcription-silencing protein Clr2 Smg8_Smg9 PF10220.9 CDJ62990.1 - 0.6 8.4 8.5 0.72 8.1 8.5 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Cwf_Cwc_15 PF04889.12 CDJ62990.1 - 0.65 9.7 9.8 0.9 9.2 9.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1645 PF07816.11 CDJ62990.1 - 0.72 10.4 17.3 1.1 9.8 17.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Plasmodium_Vir PF05795.11 CDJ62990.1 - 1.6 8.0 6.7 2 7.8 6.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.16 CDJ62990.1 - 2.3 8.2 5.9 2.9 7.9 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AIF_C PF14721.6 CDJ62990.1 - 2.5 8.4 6.1 39 4.6 4.4 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SUZ PF12752.7 CDJ62990.1 - 2.8 8.8 10.2 0.65 10.8 2.2 2.5 2 0 0 2 2 2 0 SUZ domain Paf1 PF03985.13 CDJ62990.1 - 3.8 6.4 10.6 5.5 5.9 10.6 1.2 1 0 0 1 1 1 0 Paf1 MscS_TM PF12794.7 CDJ62990.1 - 4.9 5.9 7.4 6.7 5.5 7.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4820 PF16091.5 CDJ62990.1 - 5.1 6.4 13.8 8.6 5.6 13.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) CCDC24 PF15669.5 CDJ62990.1 - 6.5 6.6 12.3 9.6 6.0 12.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Herpes_pp85 PF04637.12 CDJ62990.1 - 7.2 4.9 8.7 8.1 4.7 8.7 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PI3K_1B_p101 PF10486.9 CDJ62990.1 - 8.8 4.0 11.8 11 3.7 11.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Glyco_hydro_9 PF00759.19 CDJ62991.1 - 0.1 12.0 16.8 0.14 11.6 16.8 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 BAF1_ABF1 PF04684.13 CDJ62991.1 - 1 8.4 26.1 1.1 8.2 26.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4366 PF14283.6 CDJ62991.1 - 4.5 7.3 14.1 0.94 9.5 10.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Zea_mays_MuDR PF05928.11 CDJ62991.1 - 7.3 6.2 9.6 9.8 5.7 9.6 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) SARAF PF06682.12 CDJ62991.1 - 8 6.0 28.5 11 5.6 28.5 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SUIM_assoc PF16619.5 CDJ62992.1 - 0.00038 20.5 0.9 0.00038 20.5 0.9 7.7 5 2 1 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 BUD22 PF09073.10 CDJ62992.1 - 2.9 7.1 36.7 0.057 12.8 12.8 3.2 3 0 0 3 3 3 0 BUD22 MMR_HSR1 PF01926.23 CDJ62993.1 - 4.3e-15 55.8 0.0 7.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TrmE_N PF10396.9 CDJ62993.1 - 4e-09 36.8 0.0 1.7e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus Dynamin_N PF00350.23 CDJ62993.1 - 0.005 16.9 0.0 0.024 14.7 0.0 2.1 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 CDJ62993.1 - 0.0056 16.6 0.9 1.7 8.5 0.0 2.8 2 1 1 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 CDJ62993.1 - 0.007 15.7 0.0 0.2 11.0 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 CDJ62993.1 - 0.019 15.5 0.1 0.1 13.1 0.0 2.3 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 CDJ62993.1 - 0.046 13.1 0.1 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 CDJ62993.1 - 0.14 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 CDJ62993.1 - 0.17 11.6 0.0 0.61 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain BRF1 PF07741.13 CDJ62993.1 - 0.48 10.8 4.1 13 6.2 0.0 3.4 3 0 0 3 3 3 0 Brf1-like TBP-binding domain SPX PF03105.19 CDJ62993.1 - 1.1 9.1 20.6 0.028 14.3 6.8 2.8 3 0 0 3 3 3 0 SPX domain CC2-LZ PF16516.5 CDJ62995.1 - 0.0062 16.9 1.2 0.011 16.1 1.2 1.3 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator YjeF_N PF03853.15 CDJ62996.1 - 0.014 15.3 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 YjeF-related protein N-terminus YjeF_N PF03853.15 CDJ62997.1 - 1.7e-22 80.1 0.0 3.5e-22 79.1 0.0 1.4 1 1 0 1 1 1 1 YjeF-related protein N-terminus DUF2844 PF11005.8 CDJ62997.1 - 8.8e-05 22.5 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2844) Mitofilin PF09731.9 CDJ62998.1 - 1.8e-05 23.8 6.6 2.3e-05 23.4 6.6 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein tRNA-synt_2d PF01409.20 CDJ62998.1 - 1.9e-05 24.3 0.0 0.00021 20.9 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Lin-8 PF03353.15 CDJ62998.1 - 0.0012 18.5 8.1 0.0014 18.2 8.1 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Hid1 PF12722.7 CDJ62998.1 - 0.0017 16.6 3.9 0.0021 16.3 3.9 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein DUF2407_C PF13373.6 CDJ62998.1 - 0.028 14.6 4.6 0.053 13.7 4.6 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain Glycophorin_A PF01102.18 CDJ62998.1 - 0.12 12.7 1.2 0.22 11.8 0.4 1.9 1 1 0 1 1 1 0 Glycophorin A Zip PF02535.22 CDJ62998.1 - 0.13 11.4 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Suf PF05843.14 CDJ62998.1 - 0.15 12.0 17.7 0.3 11.0 17.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) OATP PF03137.20 CDJ62998.1 - 0.21 9.8 1.1 0.36 9.1 1.1 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAM60A PF15396.6 CDJ62998.1 - 0.36 10.8 9.4 0.57 10.2 9.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TMEM223 PF14640.6 CDJ62998.1 - 0.81 9.8 0.0 0.81 9.8 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 223 DUF2126 PF09899.9 CDJ62998.1 - 1.4 6.9 7.0 2 6.4 7.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SARAF PF06682.12 CDJ62998.1 - 2.1 7.9 16.0 2.9 7.5 16.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF755 PF05501.11 CDJ62999.1 - 0.027 14.7 36.2 0.027 14.7 36.2 5.4 3 2 2 5 5 5 0 Domain of unknown function (DUF755) Otopetrin PF03189.13 CDJ62999.1 - 0.28 9.9 7.8 8.8 5.0 7.8 2.7 1 1 0 1 1 1 0 Otopetrin DUF2722 PF10846.8 CDJ63001.1 - 0.0035 16.3 6.7 0.0035 16.3 6.7 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ63002.1 - 0.081 13.0 4.7 0.14 12.2 4.7 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LRR_9 PF14580.6 CDJ63003.1 - 5.4e-12 45.6 0.0 1.5e-06 27.8 0.2 2.8 2 1 0 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CDJ63003.1 - 1.6e-07 31.5 3.3 0.014 15.8 0.0 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ63003.1 - 0.0031 17.3 7.5 0.55 10.0 0.1 3.9 2 2 1 3 3 3 2 Leucine rich repeat SR-25 PF10500.9 CDJ63003.1 - 0.51 9.9 8.9 0.77 9.3 8.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ63003.1 - 1.4 9.6 7.2 3.3 8.4 7.2 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Arf PF00025.21 CDJ63004.1 - 3.5e-20 72.2 0.1 2.4e-18 66.2 0.1 2.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDJ63004.1 - 1.6e-09 38.0 0.0 1.6e-09 38.0 0.0 3.0 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ63004.1 - 1e-05 25.0 1.5 0.00031 20.2 1.5 2.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CDJ63004.1 - 1.1e-05 25.1 0.1 4.1e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Ras family G-alpha PF00503.20 CDJ63004.1 - 0.00079 18.7 13.2 0.0044 16.2 0.8 3.3 1 1 1 3 3 3 2 G-protein alpha subunit RskA PF10099.9 CDJ63004.1 - 0.011 16.0 9.4 0.011 16.0 9.4 3.0 2 1 0 3 3 3 0 Anti-sigma-K factor rskA GTP_EFTU PF00009.27 CDJ63004.1 - 0.079 12.5 1.6 0.48 9.9 1.2 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 CDJ63004.1 - 0.12 11.5 1.8 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 CDJ63004.1 - 0.15 12.6 0.0 0.15 12.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CDJ63004.1 - 0.35 10.6 0.0 0.35 10.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain TFB6 PF17110.5 CDJ63004.1 - 1.4 8.6 9.7 2.5 7.8 0.8 2.4 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH eIF-3_zeta PF05091.12 CDJ63004.1 - 2.4 7.0 23.3 0.17 10.9 2.4 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MecA PF05389.12 CDJ63004.1 - 5.7 6.5 19.1 0.78 9.3 0.9 3.0 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) Pantoate_ligase PF02569.15 CDJ63006.1 - 1.4e-43 149.0 0.0 1.1e-33 116.6 0.0 2.5 1 1 1 2 2 2 2 Pantoate-beta-alanine ligase Acetyltransf_CG PF14542.6 CDJ63006.1 - 0.0017 18.4 0.0 0.004 17.3 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase TFIIA PF03153.13 CDJ63006.1 - 0.007 16.4 6.6 0.26 11.2 0.6 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Acetyltransf_1 PF00583.25 CDJ63006.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family SUIM_assoc PF16619.5 CDJ63006.1 - 0.02 14.9 22.8 0.21 11.7 7.5 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Acetyltransf_13 PF13880.6 CDJ63006.1 - 0.031 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Spt20 PF12090.8 CDJ63006.1 - 0.033 13.8 16.3 0.12 12.0 1.1 2.2 2 0 0 2 2 2 0 Spt20 family DUF4131 PF13567.6 CDJ63006.1 - 0.034 13.8 0.2 0.093 12.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Acetyltransf_7 PF13508.7 CDJ63006.1 - 0.077 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ63006.1 - 0.085 12.8 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2722 PF10846.8 CDJ63006.1 - 5.4 5.9 14.6 1.2 8.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SF-assemblin PF06705.11 CDJ63008.1 - 4.6e-20 72.0 12.5 1e-11 44.7 8.6 2.0 1 1 1 2 2 2 2 SF-assemblin/beta giardin Fes1 PF08609.10 CDJ63008.1 - 0.012 16.5 1.8 0.083 13.8 0.7 2.3 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 DGF-1_C PF11040.8 CDJ63008.1 - 0.12 12.4 0.3 17 5.5 0.0 2.7 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF3584 PF12128.8 CDJ63008.1 - 0.5 7.8 16.4 0.64 7.5 16.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 CDJ63008.1 - 0.93 9.5 4.7 0.53 10.3 0.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PvlArgDC PF01862.16 CDJ63008.1 - 3.2 7.5 7.1 1.5 8.6 0.7 2.4 1 1 1 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) TipAS PF07739.13 CDJ63008.1 - 6.9 7.3 11.2 12 6.4 3.9 3.1 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain APC_N_CC PF16689.5 CDJ63009.1 - 0.011 15.8 4.3 0.1 12.7 0.0 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain DSPc PF00782.20 CDJ63009.1 - 0.013 15.3 1.4 0.23 11.3 0.1 2.7 1 1 2 3 3 3 0 Dual specificity phosphatase, catalytic domain Herpes_UL36 PF03586.13 CDJ63009.1 - 0.1 11.9 8.3 0.93 8.8 1.0 2.3 1 1 1 2 2 2 0 Herpesvirus UL36 tegument protein TPR_2 PF07719.17 CDJ63009.1 - 0.17 12.1 0.6 34 4.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Nsp1_C PF05064.13 CDJ63009.1 - 1.4 8.7 8.9 1.7 8.5 0.1 3.2 2 1 1 3 3 3 0 Nsp1-like C-terminal region BCDHK_Adom3 PF10436.9 CDJ63009.1 - 2.5 7.9 7.4 19 5.1 7.4 2.1 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase TPR_14 PF13428.6 CDJ63009.1 - 3.8 8.6 6.7 27 6.0 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec20 PF03908.13 CDJ63009.1 - 4.2 7.4 8.9 0.65 9.9 0.9 3.2 2 2 1 3 3 3 0 Sec20 Mt_ATP-synt_B PF05405.14 CDJ63009.1 - 5.1 6.7 15.1 0.23 11.0 1.8 2.7 2 1 1 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DivIC PF04977.15 CDJ63009.1 - 7.3 6.4 24.2 3.7 7.4 1.6 4.4 3 1 1 4 4 4 0 Septum formation initiator Fez1 PF06818.15 CDJ63009.1 - 9.5 6.6 26.0 17 5.8 22.4 2.7 2 1 0 2 2 2 0 Fez1 Fez1 PF06818.15 CDJ63010.1 - 0.016 15.6 10.4 0.02 15.4 10.4 1.1 1 0 0 1 1 1 0 Fez1 TMF_TATA_bd PF12325.8 CDJ63010.1 - 0.062 13.5 11.6 0.098 12.9 3.7 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 CDJ63010.1 - 1.2 8.5 9.9 1.2 8.4 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 CDJ63010.1 - 1.5 8.9 18.7 0.54 10.3 5.2 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FUSC PF04632.12 CDJ63010.1 - 7 5.1 8.4 7.8 4.9 8.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family WASH-7_C PF14746.6 CDJ63010.1 - 7.8 6.1 7.2 2 8.1 1.9 1.9 1 1 1 2 2 2 0 WASH complex subunit 7, C-terminal PheRS_DBD1 PF18552.1 CDJ63011.1 - 0.037 13.8 0.0 0.096 12.5 0.0 1.8 1 0 0 1 1 1 0 PheRS DNA binding domain 1 TMF_TATA_bd PF12325.8 CDJ63011.1 - 0.12 12.6 22.5 0.023 14.9 7.5 3.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4763 PF15960.5 CDJ63011.1 - 0.13 11.5 22.5 0.42 9.9 6.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF3450 PF11932.8 CDJ63011.1 - 1 8.6 22.2 0.29 10.4 6.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Sec2p PF06428.11 CDJ63011.1 - 1.8 8.6 21.5 0.12 12.4 6.2 3.2 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Spc7 PF08317.11 CDJ63011.1 - 2.6 6.8 23.6 1.9 7.3 7.8 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 CDJ63011.1 - 3.5 7.7 20.4 4.5 7.3 5.9 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 CDJ63011.1 - 5 6.4 21.3 13 5.0 21.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliJ PF02050.16 CDJ63011.1 - 7.6 6.8 29.3 1.9 8.7 12.0 3.0 2 0 0 2 2 2 0 Flagellar FliJ protein zf-C2H2 PF00096.26 CDJ63014.1 - 0.00024 21.4 1.2 0.00046 20.5 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CDJ63014.1 - 0.0088 16.7 0.0 0.0088 16.7 0.0 3.1 2 1 2 4 4 4 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 CDJ63014.1 - 0.037 14.8 0.8 0.087 13.7 0.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ63014.1 - 0.058 13.7 1.7 0.17 12.2 1.7 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CDJ63014.1 - 0.059 13.3 0.1 0.092 12.7 0.1 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type DUF5320 PF17253.2 CDJ63014.1 - 0.12 13.5 0.7 0.12 13.5 0.7 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5320) XPA_N PF01286.18 CDJ63014.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 XPA protein N-terminal ARS2 PF04959.13 CDJ63014.1 - 3.2 8.1 10.1 0.091 13.1 1.6 2.5 2 1 0 2 2 2 0 Arsenite-resistance protein 2 zf-CCHC PF00098.23 CDJ63016.1 - 0.0011 18.9 2.9 0.0021 18.0 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ63016.1 - 0.033 13.9 0.4 0.052 13.3 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ63016.1 - 2.8 7.7 8.7 0.2 11.4 3.1 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Ephrin_rec_like PF07699.13 CDJ63019.1 - 0.028 14.2 27.4 0.022 14.5 6.3 4.0 2 1 1 3 3 3 0 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 CDJ63022.1 - 0.015 15.1 3.7 0.015 15.1 3.7 17.4 7 6 11 19 19 19 0 Putative ephrin-receptor like HrcA_DNA-bdg PF03444.15 CDJ63022.1 - 1.3 8.8 2.3 26 4.6 0.1 3.5 3 0 0 3 3 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DUF2888 PF11135.8 CDJ63024.1 - 0.071 13.1 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2888) SlyX PF04102.12 CDJ63026.1 - 0.0016 19.0 0.9 0.0016 19.0 0.9 13.9 4 2 7 12 12 12 4 SlyX TolA_bind_tri PF16331.5 CDJ63026.1 - 0.0065 16.5 2.2 0.0065 16.5 2.2 11.8 9 3 3 12 12 12 2 TolA binding protein trimerisation EF-hand_7 PF13499.6 CDJ63027.1 - 2e-17 63.4 0.2 3.1e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ63027.1 - 4.7e-16 57.1 0.5 1.5e-07 30.4 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CDJ63027.1 - 8.2e-15 53.4 3.3 2.6e-07 30.0 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_9 PF14658.6 CDJ63027.1 - 1.7e-13 50.6 0.0 9.4e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ63027.1 - 4.4e-10 39.2 2.1 8.4e-05 22.3 0.3 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CDJ63027.1 - 9.2e-07 28.1 1.3 1.7e-05 24.1 0.3 2.8 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.13 CDJ63027.1 - 0.2 11.7 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Peptidase_S9 PF00326.21 CDJ63028.1 - 7.7e-31 107.2 0.0 9.1e-22 77.6 0.0 2.8 3 0 0 3 3 3 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CDJ63028.1 - 0.032 13.8 0.0 0.032 13.8 0.0 4.4 3 2 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) TraT PF05818.12 CDJ63028.1 - 0.082 12.6 0.1 0.082 12.6 0.1 4.3 4 0 0 4 4 4 0 Enterobacterial TraT complement resistance protein Esterase PF00756.20 CDJ63028.1 - 0.082 12.5 0.1 0.082 12.5 0.1 2.7 2 1 0 2 2 2 0 Putative esterase Virul_Fac PF10139.9 CDJ63029.1 - 0.72 8.0 18.9 0.92 7.6 18.9 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor Myosin_head PF00063.21 CDJ63030.1 - 2e-170 568.3 0.1 3e-170 567.7 0.1 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) ICMT PF04140.14 CDJ63032.1 - 6.9e-22 77.7 0.5 6.9e-22 77.7 0.5 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDJ63032.1 - 2.5e-09 37.5 0.4 8e-09 35.9 0.4 1.9 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 CDJ63032.1 - 0.00047 19.7 1.6 0.00047 19.7 1.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 CDJ63032.1 - 0.0029 16.4 2.3 0.0049 15.7 2.3 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ribosomal_60s PF00428.19 CDJ63032.1 - 0.078 13.6 4.4 0.2 12.3 4.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Siva PF05458.12 CDJ63032.1 - 0.11 12.1 2.1 0.22 11.2 2.1 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF3446 PF11928.8 CDJ63032.1 - 0.98 9.8 17.4 0.045 14.0 11.2 1.9 2 0 0 2 2 2 0 Early growth response N-terminal domain AF-4 PF05110.13 CDJ63032.1 - 1.1 7.3 7.6 1.4 6.9 7.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein X PF00739.19 CDJ63032.1 - 1.4 9.0 6.8 23 5.1 3.4 2.3 2 0 0 2 2 2 0 Trans-activation protein X Chorion_2 PF03964.15 CDJ63032.1 - 2 9.3 13.2 0.18 12.7 2.2 2.3 2 0 0 2 2 2 0 Chorion family 2 Herpes_pp85 PF04637.12 CDJ63032.1 - 7.6 4.8 8.5 11 4.3 8.5 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Spc7_N PF15402.6 CDJ63034.1 - 2.9 6.0 4.2 1.3 7.2 0.4 1.8 2 0 0 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 Ion_trans PF00520.31 CDJ63035.1 - 0.00067 19.0 9.6 0.00092 18.5 9.6 1.1 1 0 0 1 1 1 1 Ion transport protein TNFR_16_TM PF18422.1 CDJ63035.1 - 0.25 11.3 1.6 0.57 10.2 1.6 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF5090 PF17009.5 CDJ63035.1 - 0.38 10.7 6.2 0.53 10.2 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) PCI PF01399.27 CDJ63037.1 - 2.2e-09 37.8 0.0 7.3e-09 36.1 0.0 2.0 1 0 0 1 1 1 1 PCI domain GNAT_acetyltr_2 PF13718.6 CDJ63038.1 - 0.0021 17.5 0.1 0.0035 16.8 0.1 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Suf PF05843.14 CDJ63038.1 - 0.035 14.1 2.9 0.062 13.3 2.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ63038.1 - 0.061 12.1 2.1 0.084 11.6 2.1 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ63038.1 - 0.39 9.7 6.6 0.53 9.2 6.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM176 PF14851.6 CDJ63038.1 - 2.5 7.8 4.6 4.2 7.0 4.6 1.3 1 0 0 1 1 1 0 FAM176 family DUF2722 PF10846.8 CDJ63038.1 - 6.7 5.5 20.1 9.5 5.0 20.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ63038.1 - 6.8 7.3 14.1 12 6.5 14.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SNAP PF14938.6 CDJ63039.1 - 0.085 12.3 13.9 0.11 11.9 13.4 1.4 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP Baculo_PP31 PF05311.11 CDJ63040.1 - 0.017 14.6 0.1 0.019 14.5 0.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Pkinase PF00069.25 CDJ63041.1 - 3e-16 59.6 0.0 4.8e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63041.1 - 1.3e-08 34.5 0.0 3.2e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ63041.1 - 3e-08 33.3 0.0 6.7e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like SUIM_assoc PF16619.5 CDJ63041.1 - 0.0059 16.7 0.3 0.018 15.1 0.3 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 APH PF01636.23 CDJ63041.1 - 0.0062 16.5 0.5 0.0062 16.5 0.5 3.5 2 1 1 4 4 4 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ63041.1 - 0.026 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ63041.1 - 0.06 12.9 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Dscam_C PF12355.8 CDJ63041.1 - 1.8 9.5 5.3 1.6 9.7 0.9 2.5 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal Pkinase_Tyr PF07714.17 CDJ63042.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ63042.1 - 0.0017 17.7 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ63042.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like IGR PF09597.10 CDJ63042.1 - 0.17 12.0 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 IGR protein motif Pro_isomerase PF00160.21 CDJ63043.1 - 1.4e-40 139.2 0.0 1.6e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Solute_trans_a PF03619.16 CDJ63045.1 - 3e-07 30.2 0.0 5.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1216 PF06746.11 CDJ63045.1 - 0.029 14.4 1.2 0.088 12.8 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) Kinase-like PF14531.6 CDJ63046.1 - 0.00014 21.3 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 CDJ63046.1 - 0.00014 21.3 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CDJ63047.1 - 5.4e-05 22.7 0.0 8.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ63047.1 - 0.0014 18.0 0.0 0.0077 15.6 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 CDJ63048.1 - 0.00016 21.1 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ63048.1 - 0.0052 16.1 0.0 0.0097 15.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ63048.1 - 0.022 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase CSRNP_N PF16019.5 CDJ63049.1 - 0.076 12.9 4.2 0.087 12.7 4.2 1.0 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CAP59_mtransfer PF11735.8 CDJ63049.1 - 0.077 12.7 1.3 0.085 12.5 1.3 1.1 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Dsh_C PF12316.8 CDJ63049.1 - 5.2 7.4 7.0 6.1 7.2 7.0 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal UCH PF00443.29 CDJ63051.1 - 2.3e-22 79.7 0.0 5e-21 75.3 0.0 3.1 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ63051.1 - 2.5e-07 30.6 0.2 9.7e-06 25.4 2.7 4.7 5 0 0 5 5 5 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CDJ63051.1 - 1 10.1 4.0 5.6 7.7 0.0 3.7 4 0 0 4 4 4 0 DUSP domain Acyltransferase PF01553.21 CDJ63053.1 - 2.4e-08 33.7 0.0 4.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Arm PF00514.23 CDJ63054.1 - 0.0011 18.9 0.5 10 6.3 0.0 4.1 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat SIL1 PF16782.5 CDJ63054.1 - 0.0041 16.4 0.0 0.0041 16.4 0.0 3.0 2 2 1 3 3 3 1 Nucleotide exchange factor SIL1 Atx10homo_assoc PF09759.9 CDJ63054.1 - 0.034 14.2 0.1 0.5 10.4 0.0 2.7 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF2999 PF11212.8 CDJ63054.1 - 0.038 14.3 1.1 0.71 10.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2999) FPL PF09758.9 CDJ63054.1 - 0.052 13.6 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein Totivirus_coat PF05518.11 CDJ63054.1 - 1.2 7.1 13.6 1.9 6.4 13.6 1.3 1 0 0 1 1 1 0 Totivirus coat protein Nucleo_P87 PF07267.11 CDJ63054.1 - 1.7 7.4 16.1 3.3 6.5 16.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Fumerase PF05681.14 CDJ63055.1 - 3.5e-83 279.1 0.0 4.6e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 CDJ63055.1 - 1.1e-82 276.4 0.0 1.7e-82 275.8 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus IQ PF00612.27 CDJ63057.1 - 0.0043 16.7 2.1 0.0043 16.7 2.1 3.3 3 0 0 3 3 3 1 IQ calmodulin-binding motif SNF2_N PF00176.23 CDJ63059.1 - 2.1e-24 85.9 0.5 7.7e-18 64.3 0.0 3.5 2 2 0 2 2 2 2 SNF2 family N-terminal domain Glycos_transf_4 PF00953.21 CDJ63061.1 - 1.8e-20 73.6 13.5 5.7e-13 49.1 1.0 3.0 3 0 0 3 3 3 2 Glycosyl transferase family 4 Phage_holin_2_1 PF04971.12 CDJ63061.1 - 1.7 8.7 4.7 1 9.4 0.1 2.7 3 0 0 3 3 3 0 Bacteriophage P21 holin S Fer2_3 PF13085.6 CDJ63062.1 - 2.5e-30 104.7 0.0 4.6e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CDJ63062.1 - 5.4e-10 39.7 4.8 5.4e-10 39.7 4.8 2.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CDJ63062.1 - 3.8e-07 30.4 16.7 9.5e-07 29.2 5.2 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDJ63062.1 - 3.8e-06 26.9 2.7 3.8e-06 26.9 2.7 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CDJ63062.1 - 0.004 17.1 4.6 0.042 13.8 1.2 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CDJ63062.1 - 0.0071 16.9 4.9 0.0071 16.9 4.9 2.8 2 2 0 2 2 2 1 4Fe-4S dicluster domain Ribosomal_L5_C PF00673.21 CDJ63063.1 - 1.5e-22 79.5 0.0 2.3e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CDJ63063.1 - 1.3e-20 73.5 0.0 2.5e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CDJ63063.1 - 0.25 11.1 0.2 0.25 11.1 0.2 1.7 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Inhibitor_I68 PF10468.9 CDJ63066.1 - 0.14 12.6 1.2 0.33 11.4 1.2 1.6 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 ADH_zinc_N PF00107.26 CDJ63067.1 - 2.1e-24 85.9 0.1 3.1e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDJ63067.1 - 7.2e-16 58.0 2.5 7.2e-16 58.0 2.5 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CDJ63067.1 - 0.00017 21.2 0.2 0.00032 20.3 0.2 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 CDJ63067.1 - 0.00032 20.3 0.1 0.00045 19.8 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 CDJ63067.1 - 0.0025 17.1 0.3 0.0038 16.5 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.25 CDJ63068.1 - 2.2e-68 230.5 0.0 2.6e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63068.1 - 9.7e-34 116.8 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ63068.1 - 3e-07 30.1 0.0 2.4e-05 23.8 0.0 2.7 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 CDJ63068.1 - 1.5e-05 24.4 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ63068.1 - 0.00033 20.7 0.0 0.18 11.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ63068.1 - 0.032 13.8 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Cytokin-bind PF09265.10 CDJ63068.1 - 0.13 11.6 0.0 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding RRM_1 PF00076.22 CDJ63069.1 - 1.8e-18 66.1 0.0 2.7e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ63069.1 - 0.0058 16.6 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RhoGEF67_u2 PF16614.5 CDJ63069.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 FlhD PF05247.13 CDJ63072.1 - 0.063 13.6 0.2 0.44 10.8 0.0 2.4 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhD) Porin_3 PF01459.22 CDJ63074.1 - 1.3e-22 80.6 0.0 1.9e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic porin His_Phos_1 PF00300.22 CDJ63075.1 - 0.071 12.8 0.0 0.91 9.2 0.0 2.3 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) Aminotran_5 PF00266.19 CDJ63076.1 - 1.1e-48 166.0 0.0 3.9e-47 161.0 0.0 2.2 2 1 0 2 2 2 2 Aminotransferase class-V DUF202 PF02656.15 CDJ63077.1 - 1.6 9.2 6.0 1 9.9 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) PIN_8 PF18476.1 CDJ63077.1 - 3.2 7.6 6.5 6 6.7 6.5 1.5 1 0 0 1 1 1 0 PIN like domain CCDC24 PF15669.5 CDJ63078.1 - 0.13 12.1 2.7 0.37 10.6 2.7 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family ETRAMP PF09716.10 CDJ63079.1 - 0.0091 16.0 0.1 0.0091 16.0 0.1 3.5 3 0 0 3 3 3 1 Malarial early transcribed membrane protein (ETRAMP) DUF4667 PF15700.5 CDJ63079.1 - 0.04 14.0 0.3 0.04 14.0 0.3 2.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ63079.1 - 0.1 12.5 0.3 0.27 11.1 0.4 1.6 2 0 0 2 2 2 0 SPX domain FA_desaturase PF00487.24 CDJ63079.1 - 0.14 11.9 0.0 0.14 11.9 0.0 3.4 2 1 0 3 3 3 0 Fatty acid desaturase HGTP_anticodon2 PF12745.7 CDJ63079.1 - 2.8 7.4 6.5 0.36 10.3 1.9 1.7 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs FKS1_dom1 PF14288.6 CDJ63080.1 - 8.6 6.7 8.8 2.8 8.3 3.9 2.7 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 KH_2 PF07650.17 CDJ63082.1 - 3.4e-11 42.8 0.1 4.6e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 KH domain Ribosomal_S3_C PF00189.20 CDJ63082.1 - 0.00038 20.9 0.0 0.0025 18.3 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KASH PF10541.9 CDJ63082.1 - 0.047 14.0 1.2 0.086 13.1 1.2 1.4 1 0 0 1 1 1 0 Nuclear envelope localisation domain UN_NPL4 PF11543.8 CDJ63082.1 - 0.078 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 SR-25 PF10500.9 CDJ63083.1 - 0.0057 16.3 14.4 0.0057 16.3 14.4 3.1 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ63083.1 - 0.23 12.2 43.6 0.78 10.5 8.2 3.6 3 1 0 3 3 3 0 Immortalisation up-regulated protein MPM1 PF17234.2 CDJ63083.1 - 0.52 10.6 9.3 2.1 8.6 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 TFIIA PF03153.13 CDJ63083.1 - 0.59 10.1 20.3 0.6 10.0 7.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ63083.1 - 1.1 9.4 27.5 0.94 9.6 2.3 2.9 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ63083.1 - 1.7 8.2 24.1 1.3 8.6 5.9 2.2 2 0 0 2 2 2 0 Spt20 family Methyltransf_34 PF11312.8 CDJ63083.1 - 4.5 6.4 7.8 1 8.5 2.7 1.9 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase K_channel_TID PF07941.11 CDJ63084.1 - 5.2 7.6 22.2 1.1 9.8 9.3 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Scs3p PF10261.9 CDJ63085.1 - 0.33 10.4 8.2 2 7.8 0.9 3.3 3 0 0 3 3 3 0 Inositol phospholipid synthesis and fat-storage-inducing TM Sporozoite_P67 PF05642.11 CDJ63085.1 - 0.68 7.9 0.0 0.68 7.9 0.0 4.1 3 2 1 4 4 4 0 Sporozoite P67 surface antigen BNR_3 PF13859.6 CDJ63085.1 - 7 5.8 9.6 19 4.4 9.6 1.7 1 0 0 1 1 1 0 BNR repeat-like domain Ank_4 PF13637.6 CDJ63086.1 - 9.3e-09 35.7 12.2 0.0011 19.5 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ63086.1 - 8.7e-06 25.9 8.2 0.013 15.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ63086.1 - 1.4e-05 25.5 6.4 0.27 11.9 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ63086.1 - 2.1e-05 24.8 6.3 0.094 13.2 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat LRR_8 PF13855.6 CDJ63086.1 - 0.00017 21.3 21.4 0.00026 20.7 5.4 2.7 2 1 1 3 3 3 2 Leucine rich repeat Ank_3 PF13606.6 CDJ63086.1 - 0.00048 20.4 8.6 1.1 10.0 0.1 5.7 5 0 0 5 5 5 2 Ankyrin repeat Caldesmon PF02029.15 CDJ63086.1 - 0.0006 18.7 21.8 0.0006 18.7 21.8 8.4 5 2 0 6 6 6 2 Caldesmon Macoilin PF09726.9 CDJ63086.1 - 0.0014 17.3 3.7 0.0014 17.3 3.7 12.9 8 3 0 10 10 10 1 Macoilin family LRR_4 PF12799.7 CDJ63086.1 - 2 8.9 10.0 5.3 7.6 6.8 2.6 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF572 PF04502.13 CDJ63087.1 - 0.7 9.5 3.5 1.3 8.6 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) Shisa PF13908.6 CDJ63087.1 - 1 9.6 10.2 0.065 13.5 2.9 2.5 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Pkinase PF00069.25 CDJ63090.1 - 2.7e-14 53.2 0.0 4.8e-13 49.1 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63090.1 - 1.4e-06 27.8 0.1 2.4e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIA PF03153.13 CDJ63090.1 - 0.00042 20.5 30.1 0.011 15.7 16.0 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ63090.1 - 0.0047 16.6 28.1 0.089 12.4 17.2 2.3 2 0 0 2 2 2 2 Spt20 family SR-25 PF10500.9 CDJ63090.1 - 0.013 15.1 21.9 0.013 15.1 21.9 3.5 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein SAGA-Tad1 PF12767.7 CDJ63090.1 - 0.25 11.1 8.9 2.3 7.9 6.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Kdo PF06293.14 CDJ63090.1 - 0.6 9.4 10.0 0.017 14.5 3.3 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_14 PF17959.1 CDJ63090.1 - 2.3 8.6 5.1 1.2 9.5 0.8 2.1 2 0 0 2 2 2 0 EF-hand domain MPM1 PF17234.2 CDJ63090.1 - 2.7 8.2 9.9 2.5 8.3 6.6 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 BRF1 PF07741.13 CDJ63090.1 - 3.2 8.1 10.0 4 7.9 6.1 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain AP2 PF00847.20 CDJ63091.1 - 6.1e-10 39.2 1.2 6.1e-10 39.2 1.2 5.6 5 0 0 5 5 5 1 AP2 domain Spt20 PF12090.8 CDJ63092.1 - 0.00037 20.2 28.3 0.00044 19.9 28.3 1.3 1 0 0 1 1 1 1 Spt20 family Pex14_N PF04695.13 CDJ63092.1 - 0.00045 20.9 19.8 0.0005 20.8 19.8 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region MAM33 PF02330.16 CDJ63092.1 - 0.002 18.1 4.3 0.0022 18.0 4.3 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein ABC2_membrane_2 PF12679.7 CDJ63092.1 - 0.012 14.9 3.1 0.015 14.6 3.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein SpoIIP PF07454.11 CDJ63092.1 - 0.057 12.9 8.6 0.058 12.8 8.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) BAF1_ABF1 PF04684.13 CDJ63092.1 - 0.058 12.5 12.4 0.065 12.3 12.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ63092.1 - 0.092 12.7 36.3 0.093 12.7 36.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 CDJ63092.1 - 0.12 12.0 4.3 0.15 11.7 4.3 1.2 1 0 0 1 1 1 0 FAM176 family DUF2076 PF09849.9 CDJ63092.1 - 0.15 12.1 28.0 0.16 12.0 28.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) G6B PF15096.6 CDJ63092.1 - 0.19 11.5 4.3 0.23 11.2 4.3 1.1 1 0 0 1 1 1 0 G6B family Mem_trans PF03547.18 CDJ63092.1 - 0.26 9.6 2.4 0.3 9.5 2.4 1.1 1 0 0 1 1 1 0 Membrane transport protein EPL1 PF10513.9 CDJ63092.1 - 0.29 11.5 10.7 0.34 11.3 10.7 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Folate_carrier PF01770.18 CDJ63092.1 - 0.34 9.6 4.3 0.38 9.4 4.3 1.2 1 0 0 1 1 1 0 Reduced folate carrier TERB2 PF15101.6 CDJ63092.1 - 0.35 10.9 15.6 0.41 10.7 15.6 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4770 PF15994.5 CDJ63092.1 - 0.49 10.6 12.0 0.57 10.4 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Connexin PF00029.19 CDJ63092.1 - 0.69 9.6 6.7 0.69 9.6 6.7 1.2 1 0 0 1 1 1 0 Connexin eIF-3_zeta PF05091.12 CDJ63092.1 - 0.87 8.5 19.1 0.95 8.4 19.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) OATP PF03137.20 CDJ63092.1 - 0.92 7.7 4.6 0.92 7.7 4.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family HGTP_anticodon2 PF12745.7 CDJ63092.1 - 0.93 8.9 15.4 1.1 8.7 15.4 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs MMR1 PF08505.10 CDJ63092.1 - 1 9.6 16.8 1.1 9.5 16.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein YfhO PF09586.10 CDJ63092.1 - 1.1 7.4 5.1 1.3 7.2 5.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1387 PF07139.11 CDJ63092.1 - 1.3 8.7 15.0 1.3 8.7 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) EOS1 PF12326.8 CDJ63092.1 - 1.3 9.0 5.6 1.4 8.8 5.6 1.2 1 0 0 1 1 1 0 N-glycosylation protein Gti1_Pac2 PF09729.9 CDJ63092.1 - 1.4 9.0 9.4 1.6 8.8 9.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Miga PF10265.9 CDJ63092.1 - 1.5 7.7 12.2 1.8 7.5 12.2 1.0 1 0 0 1 1 1 0 Mitoguardin BORG_CEP PF14957.6 CDJ63092.1 - 1.6 9.9 8.0 1.9 9.7 8.0 1.2 1 0 0 1 1 1 0 Cdc42 effector Het-C PF07217.11 CDJ63092.1 - 1.7 7.1 10.1 1.8 7.0 10.1 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Sec62 PF03839.16 CDJ63092.1 - 2 7.9 9.2 2 7.8 9.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 SRP-alpha_N PF04086.13 CDJ63092.1 - 2.1 8.2 17.6 2.5 7.9 17.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RBP_receptor PF14752.6 CDJ63092.1 - 2.3 6.7 9.4 2.8 6.4 9.4 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor CLN3 PF02487.17 CDJ63092.1 - 2.5 7.1 8.6 2.7 6.9 8.6 1.1 1 0 0 1 1 1 0 CLN3 protein V_ATPase_I PF01496.19 CDJ63092.1 - 2.7 5.8 11.3 2.7 5.8 11.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Band_3_cyto PF07565.13 CDJ63092.1 - 2.7 7.7 11.4 3 7.6 11.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ctr PF04145.15 CDJ63092.1 - 2.8 8.5 8.7 3.6 8.2 8.7 1.2 1 0 0 1 1 1 0 Ctr copper transporter family UPF0560 PF10577.9 CDJ63092.1 - 3 6.2 18.3 3.3 6.1 18.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4638 PF15472.6 CDJ63092.1 - 3.1 7.5 11.7 3.4 7.3 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) FTZ PF03867.14 CDJ63092.1 - 3.1 7.2 15.6 4.5 6.7 15.6 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region CPSF100_C PF13299.6 CDJ63092.1 - 3.3 7.9 12.9 4.1 7.6 12.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NST1 PF13945.6 CDJ63092.1 - 3.7 7.6 19.9 5.2 7.1 19.9 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Neur_chan_memb PF02932.16 CDJ63092.1 - 3.9 7.5 14.2 4.1 7.4 14.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ63092.1 - 4 6.2 14.3 4.5 6.0 14.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 CDJ63092.1 - 4.1 6.1 18.5 4.6 5.9 18.5 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 CDJ63092.1 - 4.6 6.7 17.9 4.7 6.7 17.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ndc1_Nup PF09531.10 CDJ63092.1 - 4.9 5.7 15.9 5.5 5.5 15.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CSG2 PF16965.5 CDJ63092.1 - 5.4 5.8 4.7 5.4 5.9 4.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator MDM10 PF12519.8 CDJ63092.1 - 6.8 5.4 10.5 7.2 5.4 10.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Peptidase_S64 PF08192.11 CDJ63092.1 - 7 5.0 11.1 6.9 5.0 11.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 XRN_M PF17846.1 CDJ63092.1 - 7.5 5.4 12.7 8.6 5.2 12.7 1.0 1 0 0 1 1 1 0 Xrn1 helical domain SLC12 PF03522.15 CDJ63092.1 - 7.9 5.4 14.3 8.1 5.4 14.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Ten_N PF06484.12 CDJ63092.1 - 8 6.2 14.5 8.8 6.1 14.5 1.0 1 0 0 1 1 1 0 Teneurin Intracellular Region AUX_IAA PF02309.16 CDJ63092.1 - 9.3 6.0 12.7 12 5.7 12.7 1.1 1 0 0 1 1 1 0 AUX/IAA family Herpes_DNAp_acc PF04929.12 CDJ63092.1 - 9.6 5.1 11.6 11 4.8 11.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF3959 PF13105.6 CDJ63092.1 - 9.7 5.6 8.7 13 5.2 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DcuC PF03606.15 CDJ63093.1 - 0.0081 14.7 1.6 0.0081 14.7 1.6 2.6 2 1 1 3 3 3 1 C4-dicarboxylate anaerobic carrier DUF3653 PF12375.8 CDJ63093.1 - 0.034 14.2 0.4 0.034 14.2 0.4 2.2 2 0 0 2 2 2 0 Phage protein YdjM PF04307.14 CDJ63093.1 - 0.046 13.0 0.7 0.07 12.4 0.7 1.2 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase ICA69 PF04629.14 CDJ63093.1 - 0.81 9.9 34.9 0.04 14.2 10.4 2.1 2 0 0 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain FAM60A PF15396.6 CDJ63093.1 - 4.3 7.3 24.8 0.53 10.2 8.0 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Dala_Dala_lig_N PF01820.21 CDJ63093.1 - 8.5 6.9 8.6 20 5.7 2.9 3.0 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus RT_RNaseH_2 PF17919.1 CDJ63097.1 - 1.4e-27 95.7 0.1 1.7e-27 95.4 0.1 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ63097.1 - 3.6e-17 62.6 0.0 5.5e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Scramblase PF03803.15 CDJ63097.1 - 0.017 14.4 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Scramblase FAM92 PF06730.11 CDJ63097.1 - 0.02 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 FAM92 protein zf-CCHC PF00098.23 CDJ63098.1 - 8.3e-07 28.8 9.6 0.00095 19.1 1.9 2.3 2 0 0 2 2 2 2 Zinc knuckle zinc-ribbons_6 PF07191.12 CDJ63098.1 - 0.013 15.5 2.7 0.027 14.4 2.7 1.5 1 0 0 1 1 1 0 zinc-ribbons Retrotrans_gag PF03732.17 CDJ63098.1 - 0.02 15.2 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_5 PF14787.6 CDJ63098.1 - 0.66 9.7 8.0 0.31 10.8 0.9 2.4 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 CDJ63098.1 - 0.97 9.3 6.0 0.39 10.6 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 CDJ63099.1 - 1.4e-14 54.2 0.1 2.6e-14 53.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EamA PF00892.20 CDJ63101.1 - 0.0028 17.8 2.8 0.0037 17.4 2.8 1.2 1 0 0 1 1 1 1 EamA-like transporter family Collagen PF01391.18 CDJ63101.1 - 0.0041 16.8 19.8 0.0041 16.8 19.8 3.0 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) DUF2681 PF10883.8 CDJ63101.1 - 2.8 8.4 10.1 6.6 7.2 10.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Spt20 PF12090.8 CDJ63102.1 - 1 9.0 10.9 1.6 8.3 10.9 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ63102.1 - 6.8 6.8 18.9 0.22 11.6 8.5 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_S7 PF00177.21 CDJ63103.1 - 3.5e-37 127.3 1.7 4.5e-37 127.0 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_L6e PF01159.19 CDJ63103.1 - 0.09 13.3 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L6e Spt20 PF12090.8 CDJ63104.1 - 0.015 14.9 13.8 0.015 15.0 13.8 1.1 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 CDJ63104.1 - 0.062 14.0 12.8 0.088 13.5 12.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ63104.1 - 0.063 13.3 17.3 0.081 12.9 17.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ63104.1 - 0.27 10.1 11.3 0.3 10.0 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF908 PF06012.12 CDJ63104.1 - 0.45 9.9 4.4 0.49 9.8 4.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Presenilin PF01080.17 CDJ63104.1 - 0.58 8.9 3.2 0.54 9.0 3.2 1.1 1 0 0 1 1 1 0 Presenilin DUF3138 PF11336.8 CDJ63104.1 - 5.8 5.4 11.8 7.9 5.0 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) BT1 PF03092.16 CDJ63106.1 - 8.1e-76 255.3 16.0 7.5e-73 245.5 16.0 2.1 1 1 0 1 1 1 1 BT1 family DUF1614 PF07758.11 CDJ63106.1 - 0.007 16.4 0.8 0.016 15.2 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1614) Pkinase PF00069.25 CDJ63107.1 - 3.5e-27 95.4 0.0 4.8e-26 91.7 0.0 2.8 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63107.1 - 5.7e-12 45.5 0.0 5.2e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Borrelia_P83 PF05262.11 CDJ63107.1 - 1.1 7.6 9.9 1.6 7.2 9.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 CDJ63107.1 - 2.2 7.0 17.0 4.3 6.0 17.0 1.4 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ63107.1 - 9.5 4.3 28.5 17 3.5 28.5 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 5-FTHF_cyc-lig PF01812.20 CDJ63108.1 - 7.4e-13 48.8 0.0 2.7e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family EPL1 PF10513.9 CDJ63109.1 - 0.00015 22.2 0.4 0.00015 22.2 0.4 2.6 2 1 0 2 2 2 1 Enhancer of polycomb-like TipAS PF07739.13 CDJ63109.1 - 0.18 12.3 5.9 0.66 10.5 5.9 2.0 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain TPR_2 PF07719.17 CDJ63110.1 - 0.0019 18.2 7.0 4.5 7.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ63110.1 - 0.0026 17.5 2.1 13 5.8 1.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ63110.1 - 0.007 16.6 7.9 1.7 9.0 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ63110.1 - 0.045 13.9 8.5 0.084 13.0 0.7 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 CDJ63110.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) SRP_TPR_like PF17004.5 CDJ63110.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_10 PF13374.6 CDJ63110.1 - 1 9.4 7.0 8.2 6.4 1.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ63110.1 - 4.1 7.7 5.6 2.4 8.4 0.4 3.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_C97 PF05903.14 CDJ63111.1 - 2e-25 89.4 0.0 8.9e-24 84.0 0.0 2.2 1 1 0 1 1 1 1 PPPDE putative peptidase domain EccE PF11203.8 CDJ63111.1 - 0.017 15.4 3.8 0.017 15.4 3.8 2.4 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE PepSY_TM PF03929.16 CDJ63111.1 - 0.15 11.7 2.2 0.23 11.1 0.3 2.1 2 0 0 2 2 2 0 PepSY-associated TM region LRR_4 PF12799.7 CDJ63113.1 - 0.016 15.7 3.4 9 6.9 0.0 5.0 5 1 0 6 6 6 0 Leucine Rich repeats (2 copies) MMR_HSR1 PF01926.23 CDJ63114.1 - 7.1e-11 42.2 0.0 1.6e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ63114.1 - 1.7e-09 37.8 0.0 4e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 CDJ63114.1 - 5.8e-06 25.9 1.5 0.31 10.6 0.1 3.2 2 1 1 3 3 3 3 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 CDJ63114.1 - 0.0016 18.5 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Arf PF00025.21 CDJ63114.1 - 0.0079 15.7 0.1 1.6 8.1 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Toprim_3 PF13362.6 CDJ63114.1 - 0.012 16.0 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Toprim domain Ras PF00071.22 CDJ63114.1 - 0.014 15.0 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 CDJ63114.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TFIIA PF03153.13 CDJ63115.1 - 2.1 8.2 38.7 0.31 11.0 14.2 2.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Na_K-ATPase PF00287.18 CDJ63115.1 - 7.9 5.6 6.2 18 4.4 6.2 1.5 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain V_ATPase_I PF01496.19 CDJ63117.1 - 1.3 6.8 7.2 2.4 5.9 7.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 CDJ63117.1 - 5.9 5.5 7.3 9.8 4.7 7.3 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PseudoU_synth_1 PF01416.20 CDJ63120.1 - 9.8e-19 67.8 0.1 2.9e-16 59.9 0.0 3.2 2 1 1 3 3 3 2 tRNA pseudouridine synthase Pkinase PF00069.25 CDJ63122.1 - 5.8e-44 150.4 1.5 8.8e-21 74.4 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63122.1 - 1.1e-17 64.2 0.0 5.9e-10 38.9 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase RT_RNaseH_2 PF17919.1 CDJ63123.1 - 2.7e-21 75.5 0.0 3.9e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ63123.1 - 2.3e-14 53.6 0.0 3.7e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDJ63124.1 - 5.3e-06 26.9 0.0 1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ63124.1 - 1.1e-05 25.9 0.0 2.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDJ63124.1 - 0.0003 20.6 0.0 0.00045 20.0 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease DDE_Tnp_1_2 PF13586.6 CDJ63124.1 - 0.03 14.7 1.3 0.44 10.9 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain Proteasome PF00227.26 CDJ63125.1 - 6.9e-56 188.7 0.0 8.5e-56 188.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ63125.1 - 1.2e-13 50.5 0.0 2.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 CDJ63125.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Carb_kinase PF01256.17 CDJ63126.1 - 8.4e-30 104.0 0.0 5.3e-18 65.4 0.0 3.6 3 0 0 3 3 3 3 Carbohydrate kinase Neur_chan_memb PF02932.16 CDJ63126.1 - 7.7 6.5 7.2 13 5.8 7.2 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AP2 PF00847.20 CDJ63128.1 - 3.5e-07 30.3 2.1 1.6e-05 25.0 0.3 3.4 2 0 0 2 2 2 2 AP2 domain Pex14_N PF04695.13 CDJ63130.1 - 0.00023 21.9 3.5 0.00023 21.9 3.5 2.0 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Pyrid_ox_like PF16242.5 CDJ63130.1 - 0.00076 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Abhydrolase_1 PF00561.20 CDJ63131.1 - 1.8e-12 47.5 0.1 4.2e-11 43.0 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ63131.1 - 6.2e-11 43.3 3.5 6.2e-11 43.3 3.5 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ63131.1 - 1e-08 34.7 0.6 5.2e-08 32.4 0.1 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CDJ63131.1 - 0.0047 16.7 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 CDJ63131.1 - 0.013 15.6 0.1 0.046 13.8 0.1 1.9 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.12 CDJ63131.1 - 0.034 14.1 0.0 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) LIDHydrolase PF10230.9 CDJ63131.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase CIAPIN1 PF05093.13 CDJ63134.1 - 0.043 14.3 0.8 0.043 14.3 0.8 2.3 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Spt20 PF12090.8 CDJ63134.1 - 0.23 11.1 50.1 0.088 12.4 23.7 2.2 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 CDJ63134.1 - 0.48 11.4 21.4 0.53 11.3 8.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PIP5K PF01504.18 CDJ63134.1 - 0.72 9.0 5.1 1.3 8.2 5.1 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase MDM10 PF12519.8 CDJ63134.1 - 1.9 7.2 5.7 2.7 6.8 5.7 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF2722 PF10846.8 CDJ63134.1 - 3.1 6.6 41.2 0.16 10.9 16.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) ABC2_membrane PF01061.24 CDJ63136.1 - 0.00092 18.7 11.0 0.013 15.0 11.0 2.1 1 1 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CDJ63136.1 - 0.0061 15.7 0.2 0.01 15.0 0.2 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein Uso1_p115_C PF04871.13 CDJ63136.1 - 1.8 9.0 14.5 6.2 7.2 14.5 1.8 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Form_Nir_trans PF01226.17 CDJ63137.1 - 2e-66 223.7 16.4 2.3e-66 223.5 16.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter RhodobacterPufX PF11511.8 CDJ63137.1 - 3 7.5 6.3 6.5 6.4 1.5 3.0 2 1 1 3 3 3 0 Intrinsic membrane protein PufX DUF2722 PF10846.8 CDJ63138.1 - 0.0027 16.7 2.4 0.0033 16.4 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) FAM176 PF14851.6 CDJ63138.1 - 0.24 11.1 4.5 4.9 6.8 0.0 2.1 2 0 0 2 2 2 0 FAM176 family DUF3464 PF11947.8 CDJ63138.1 - 0.71 9.6 2.7 1.3 8.7 2.7 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TFIIA PF03153.13 CDJ63138.1 - 0.99 9.3 17.9 0.036 14.1 8.4 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ63138.1 - 1.1 8.8 16.7 1.6 8.3 16.7 1.1 1 0 0 1 1 1 0 Spt20 family RAB3GAP2_N PF14655.6 CDJ63138.1 - 7.5 5.7 6.1 10 5.3 6.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cupin_1 PF00190.22 CDJ63139.1 - 1e-05 25.2 0.0 2.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 CDJ63139.1 - 5.1e-05 22.9 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Spt20 PF12090.8 CDJ63139.1 - 0.025 14.2 26.3 0.029 14.0 13.7 2.2 2 0 0 2 2 2 0 Spt20 family AraC_binding PF02311.19 CDJ63139.1 - 0.062 13.2 0.0 0.062 13.2 0.0 2.7 3 0 0 3 3 3 0 AraC-like ligand binding domain SARAF PF06682.12 CDJ63139.1 - 0.13 11.9 29.8 0.059 13.0 9.4 3.0 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2722 PF10846.8 CDJ63139.1 - 7 5.5 24.8 1.3 7.9 13.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) PH PF00169.29 CDJ63140.1 - 0.006 17.1 0.2 0.046 14.2 0.2 2.1 1 1 0 1 1 1 1 PH domain zf-CCCH PF00642.24 CDJ63141.1 - 0.00044 20.1 18.9 0.0048 16.8 2.6 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ63141.1 - 0.0035 17.3 2.5 0.0035 17.3 2.5 3.1 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ63141.1 - 0.0064 16.3 1.1 0.0064 16.3 1.1 2.0 2 0 0 2 2 2 1 CCCH-type zinc finger Pkinase PF00069.25 CDJ63141.1 - 0.013 14.8 0.0 0.098 12.0 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain UCH PF00443.29 CDJ63142.1 - 0.15 11.6 0.2 0.15 11.6 0.2 1.6 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase SUIM_assoc PF16619.5 CDJ63142.1 - 0.18 11.9 11.7 0.23 11.5 11.7 1.3 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LCCL PF03815.19 CDJ63143.1 - 1.6e-53 178.8 0.0 6.5e-17 61.4 0.2 3.6 2 1 1 3 3 3 3 LCCL domain Rxt3 PF08642.10 CDJ63143.1 - 1.5e-08 35.4 0.0 0.00025 21.8 0.0 3.6 3 1 0 3 3 3 2 Histone deacetylation protein Rxt3 SRCR PF00530.18 CDJ63143.1 - 3.4e-08 33.9 5.5 0.0011 19.4 0.6 2.8 2 1 0 2 2 2 2 Scavenger receptor cysteine-rich domain Laminin_G_3 PF13385.6 CDJ63143.1 - 0.00059 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.17 CDJ63143.1 - 0.043 13.5 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Pentaxin family DUF3446 PF11928.8 CDJ63143.1 - 1.3 9.4 14.3 0.55 10.6 11.1 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF4148 PF13663.6 CDJ63143.1 - 2.9 8.2 8.4 3.9 7.7 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) IMUP PF15761.5 CDJ63143.1 - 3.6 8.3 16.4 2.7 8.7 13.4 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein PLAT PF01477.23 CDJ63144.1 - 6.5e-12 46.0 0.0 3.8e-10 40.3 0.0 2.8 3 0 0 3 3 3 1 PLAT/LH2 domain SUIM_assoc PF16619.5 CDJ63144.1 - 5.2e-07 29.6 0.0 1.2e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ63144.1 - 0.034 14.4 1.3 1.2 9.5 0.4 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ63144.1 - 0.099 12.6 10.1 0.14 12.1 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ63144.1 - 0.17 10.8 12.9 0.23 10.3 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Band_3_cyto PF07565.13 CDJ63144.1 - 0.19 11.5 2.3 12 5.6 4.8 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Spt20 PF12090.8 CDJ63144.1 - 0.2 11.2 16.8 0.36 10.4 16.8 1.3 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ63144.1 - 0.3 10.2 4.3 0.42 9.7 4.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Dehydrin PF00257.19 CDJ63144.1 - 6.7 7.2 10.5 0.69 10.5 6.0 1.6 2 0 0 2 2 2 0 Dehydrin PseudoU_synth_2 PF00849.22 CDJ63146.1 - 2e-07 31.3 13.2 2e-07 31.3 13.2 3.4 2 1 0 2 2 2 1 RNA pseudouridylate synthase DUF1644 PF07800.12 CDJ63146.1 - 0.00019 21.5 6.6 0.00092 19.3 1.2 5.9 3 1 2 5 5 5 2 Protein of unknown function (DUF1644) TFIIA PF03153.13 CDJ63146.1 - 0.002 18.2 4.9 0.002 18.2 4.9 4.8 3 2 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ63146.1 - 0.0022 17.0 6.7 0.0022 17.0 6.7 7.3 7 1 0 7 7 7 3 Protein of unknown function (DUF2722) DUF4179 PF13786.6 CDJ63146.1 - 0.25 11.8 1.6 2.8 8.5 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) YTH PF04146.15 CDJ63147.1 - 2.5e-26 92.6 0.0 2.5e-26 92.6 0.0 3.6 3 2 0 3 3 3 1 YT521-B-like domain DUF2722 PF10846.8 CDJ63147.1 - 0.07 12.1 0.1 0.07 12.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ63148.1 - 0.0031 17.8 13.5 0.0031 17.8 13.5 5.1 3 2 0 3 3 3 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ63148.1 - 0.027 14.5 1.2 0.027 14.5 1.2 12.8 7 4 1 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ63150.1 - 0.0042 16.7 37.2 0.0042 16.7 37.2 2.0 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein CDC27 PF09507.10 CDJ63150.1 - 2.7 7.3 47.5 3.3 7.0 47.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SOBP PF15279.6 CDJ63150.1 - 7.7 7.0 23.3 10 6.6 23.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein MFAP1 PF06991.11 CDJ63151.1 - 2.8e-63 213.7 36.0 2.8e-63 213.7 36.0 2.3 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing Velvet PF11754.8 CDJ63151.1 - 1.4 8.8 11.7 2.8 7.8 11.7 1.5 1 0 0 1 1 1 0 Velvet factor RskA PF10099.9 CDJ63152.1 - 1.1e-05 25.8 28.7 0.0072 16.6 4.1 2.9 1 1 1 2 2 2 2 Anti-sigma-K factor rskA EPL1 PF10513.9 CDJ63152.1 - 8.9 6.7 28.1 3.4 8.0 1.3 3.3 3 0 0 3 3 3 0 Enhancer of polycomb-like Surface_antigen PF11054.8 CDJ63153.1 - 5.4e-32 111.4 1.7 1e-31 110.5 1.7 1.4 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ63154.1 - 7.3e-30 104.4 0.2 8.4e-30 104.2 0.2 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ63155.1 - 1.4e-34 119.8 1.5 2.2e-34 119.2 1.5 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ63156.1 - 1e-26 94.1 1.2 1.1e-26 94.0 1.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ63157.1 - 5.6e-31 108.1 0.3 1.1e-30 107.2 0.3 1.4 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ63158.1 - 9.6e-34 117.1 2.2 1.2e-33 116.8 2.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ63159.1 - 2.5e-28 99.4 3.8 3e-28 99.2 3.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ63160.1 - 3.3e-32 112.1 2.8 2e-31 109.6 2.8 1.9 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ63161.1 - 1.9e-33 116.2 1.1 3.6e-33 115.2 1.1 1.4 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ63162.1 - 2.3e-30 106.0 1.3 3.1e-30 105.6 1.3 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ63163.1 - 1.1e-20 74.3 2.0 2.7e-20 73.1 0.6 1.8 1 1 1 2 2 2 1 Sporozoite TA4 surface antigen FAM176 PF14851.6 CDJ63165.1 - 0.095 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 FAM176 family Abhydrolase_6 PF12697.7 CDJ63166.1 - 1.8e-24 87.6 1.1 2.9e-24 86.9 1.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ63166.1 - 6.3e-08 32.6 0.7 5.3e-07 29.5 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ63166.1 - 1.2e-07 31.2 0.8 3.1e-06 26.6 0.8 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CDJ63166.1 - 0.00071 19.4 0.3 0.0012 18.7 0.3 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 CDJ63166.1 - 0.023 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 CDJ63166.1 - 0.03 14.4 0.5 0.33 11.0 0.0 2.5 3 0 0 3 3 3 0 Thioesterase domain Lipase_3 PF01764.25 CDJ63166.1 - 0.035 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DEAD PF00270.29 CDJ63167.1 - 2.9e-24 85.8 0.0 5e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ63167.1 - 0.015 15.5 0.0 0.1 12.9 0.0 2.4 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.23 CDJ63167.1 - 0.052 12.3 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_7 PF12775.7 CDJ63168.1 - 1.4e-22 80.1 0.1 2.6e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_1 PF17857.1 CDJ63168.1 - 8.7e-19 67.6 0.2 3.3e-10 40.1 0.1 2.4 1 1 1 2 2 2 2 AAA+ lid domain AAA_7 PF12775.7 CDJ63169.1 - 1.1e-24 86.9 0.0 9.3e-23 80.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 CDJ63169.1 - 1.2e-19 70.7 0.6 2.6e-19 69.6 0.6 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDJ63169.1 - 5.7e-15 55.5 0.0 1.4e-11 44.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 CDJ63169.1 - 3.4e-10 39.4 0.0 5.1e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 CDJ63169.1 - 7.5e-06 26.4 0.0 0.013 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CDJ63169.1 - 1.1e-05 25.7 0.0 0.056 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CDJ63169.1 - 4e-05 24.1 0.0 0.022 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDJ63169.1 - 0.00025 21.2 0.1 0.65 10.2 0.1 2.4 2 1 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 CDJ63169.1 - 0.00052 19.8 0.0 0.34 10.6 0.0 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CDJ63169.1 - 0.00063 19.6 0.1 0.81 9.4 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA PF00004.29 CDJ63169.1 - 0.00064 20.2 0.0 0.41 11.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CDJ63169.1 - 0.0021 17.4 0.1 0.48 9.7 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin ABC_tran PF00005.27 CDJ63169.1 - 0.0055 17.2 0.0 1.4 9.4 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Viral_helicase1 PF01443.18 CDJ63169.1 - 0.0074 16.1 0.1 0.38 10.5 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 CDJ63169.1 - 0.014 15.1 0.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 CDJ63169.1 - 0.015 15.2 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 CDJ63169.1 - 0.02 15.3 0.0 11 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase KTI12 PF08433.10 CDJ63169.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 CDJ63169.1 - 0.024 14.7 0.0 0.62 10.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase TsaE PF02367.17 CDJ63169.1 - 0.025 14.6 0.1 0.51 10.3 0.0 2.5 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CDJ63169.1 - 0.032 13.9 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CDJ63169.1 - 0.041 12.8 0.0 0.084 11.8 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 CDJ63169.1 - 0.06 13.6 0.1 4.1 7.6 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 CDJ63169.1 - 0.097 11.8 0.0 10 5.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 CDJ63169.1 - 0.12 11.8 0.0 0.87 9.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 CDJ63169.1 - 0.14 12.4 0.0 3.9 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 CDJ63170.1 - 4e-118 394.1 0.0 1.2e-66 225.0 0.0 2.0 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CDJ63170.1 - 0.00081 19.4 0.0 0.006 16.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ63170.1 - 0.0052 17.2 0.0 0.0097 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDJ63170.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ63170.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TIG PF01833.24 CDJ63171.1 - 7.3e-06 26.0 0.4 1.5e-05 25.0 0.4 1.6 1 1 0 1 1 1 1 IPT/TIG domain Filamin PF00630.19 CDJ63171.1 - 0.00012 22.9 0.0 0.00029 21.6 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat Kelch_5 PF13854.6 CDJ63171.1 - 0.0038 17.2 0.0 0.044 13.8 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 CDJ63171.1 - 0.23 11.8 1.3 50 4.4 0.1 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Ubiq_cyt_C_chap PF03981.12 CDJ63175.1 - 8.2e-08 32.4 0.5 1.1e-05 25.5 0.0 2.2 1 1 1 2 2 2 2 Ubiquinol-cytochrome C chaperone Med21 PF11221.8 CDJ63176.1 - 9.4e-08 32.4 1.5 1e-07 32.3 1.5 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Phage_GP20 PF06810.11 CDJ63176.1 - 0.0018 18.1 0.2 0.002 17.9 0.2 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF16 PF01519.16 CDJ63176.1 - 0.0051 17.3 0.4 0.007 16.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF16 GCN5L1 PF06320.13 CDJ63176.1 - 0.0072 16.5 0.5 0.0093 16.1 0.5 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Med4 PF10018.9 CDJ63176.1 - 0.0086 15.8 0.6 0.013 15.1 0.6 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 UPF0184 PF03670.13 CDJ63176.1 - 0.021 15.2 0.6 0.029 14.7 0.3 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) NRBF2 PF08961.10 CDJ63176.1 - 0.033 13.8 0.1 0.039 13.5 0.1 1.0 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Focal_AT PF03623.13 CDJ63176.1 - 0.058 13.4 0.4 0.11 12.5 0.4 1.4 1 1 0 1 1 1 0 Focal adhesion targeting region COMP PF11598.8 CDJ63176.1 - 0.062 13.8 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein FH2 PF02181.23 CDJ63176.1 - 0.067 12.3 0.1 0.075 12.1 0.1 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain CRR7 PF12095.8 CDJ63176.1 - 0.098 13.1 0.1 0.16 12.4 0.1 1.4 1 1 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 Uteroglobin PF01099.17 CDJ63176.1 - 0.12 12.8 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Uteroglobin family APG6_N PF17675.1 CDJ63176.1 - 0.22 12.0 6.2 0.27 11.7 6.2 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region TSC22 PF01166.18 CDJ63176.1 - 1.1 9.7 7.4 8.3 6.8 3.3 2.8 2 1 1 3 3 3 0 TSC-22/dip/bun family MMR_HSR1 PF01926.23 CDJ63177.1 - 3.4e-13 49.7 0.0 7.6e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CDJ63177.1 - 9.8e-05 21.8 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 CDJ63177.1 - 0.00017 21.1 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 CDJ63177.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Septin NPFF PF15085.6 CDJ63177.1 - 0.017 15.4 1.1 0.1 13.0 0.1 2.4 2 0 0 2 2 2 0 Neuropeptide FF Arf PF00025.21 CDJ63177.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Dynamin_N PF00350.23 CDJ63177.1 - 0.08 13.0 0.1 0.89 9.6 0.1 2.2 1 1 1 2 2 2 0 Dynamin family Roc PF08477.13 CDJ63177.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Actin PF00022.19 CDJ63179.1 - 3.5e-144 480.4 0.0 1.5e-143 478.3 0.0 1.7 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 CDJ63180.1 - 4.7e-48 163.8 0.0 6.4e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63180.1 - 1.9e-43 148.6 0.0 2.6e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CDJ63180.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 CDJ63180.1 - 0.021 13.8 0.3 0.042 12.8 0.3 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CDJ63180.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ63180.1 - 0.2 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AP2 PF00847.20 CDJ63182.1 - 4.2e-24 84.5 1.8 1.2e-11 44.7 0.2 2.4 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.6 CDJ63182.1 - 8.1e-16 58.1 0.2 1.4e-15 57.3 0.2 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ63183.1 - 7.5e-09 35.7 1.8 0.0032 17.7 0.0 2.4 2 0 0 2 2 2 2 AP2 domain zf-CCHC PF00098.23 CDJ63184.1 - 0.00026 20.9 4.8 0.00069 19.6 4.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ63184.1 - 0.05 13.5 3.0 0.12 12.2 3.0 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ63184.1 - 0.55 10.2 6.5 0.32 11.0 3.0 2.4 1 1 1 2 2 2 0 Zinc knuckle Whib PF02467.16 CDJ63184.1 - 0.55 10.9 4.1 1.6 9.4 4.1 1.7 1 0 0 1 1 1 0 Transcription factor WhiB zf-CCHC_4 PF14392.6 CDJ63184.1 - 2.1 8.1 5.2 0.37 10.6 1.2 1.8 2 0 0 2 2 2 0 Zinc knuckle PQQ PF01011.21 CDJ63186.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 PQQ enzyme repeat ABC_tran PF00005.27 CDJ63189.1 - 8.2e-12 45.8 0.1 1.8e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CDJ63189.1 - 1.2e-11 44.8 0.3 1.4e-11 44.6 0.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 CDJ63189.1 - 4.4e-05 23.9 0.0 0.00012 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ63189.1 - 0.0014 18.6 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CDJ63189.1 - 0.0018 18.0 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CDJ63189.1 - 0.0036 17.6 0.0 0.0096 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ63189.1 - 0.0052 16.9 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CDJ63189.1 - 0.0083 16.1 0.2 0.017 15.0 0.1 1.5 2 0 0 2 2 1 1 Rad17 P-loop domain G-alpha PF00503.20 CDJ63189.1 - 0.0091 15.2 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_25 PF13481.6 CDJ63189.1 - 0.012 15.2 0.4 0.021 14.4 0.4 1.4 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 CDJ63189.1 - 0.012 15.0 0.1 0.03 13.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Septin PF00735.18 CDJ63189.1 - 0.014 14.7 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Septin Beta-lactamase PF00144.24 CDJ63189.1 - 0.018 14.3 0.4 0.026 13.8 0.4 1.3 1 0 0 1 1 1 0 Beta-lactamase Mg_chelatase PF01078.21 CDJ63189.1 - 0.046 13.1 0.1 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 CDJ63189.1 - 0.055 13.7 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 CDJ63189.1 - 0.056 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3323 PF11796.8 CDJ63189.1 - 0.061 13.2 0.5 0.11 12.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) VirE PF05272.11 CDJ63189.1 - 0.083 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Virulence-associated protein E AAA_14 PF13173.6 CDJ63189.1 - 0.092 12.8 0.0 0.83 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDJ63189.1 - 0.097 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDJ63189.1 - 0.14 12.2 0.0 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Spore_IV_A PF09547.10 CDJ63189.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) AAA_21 PF13304.6 CDJ63189.1 - 0.19 11.5 0.0 0.35 10.6 0.0 1.4 2 0 0 2 2 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 CDJ63189.1 - 0.4 10.4 0.0 0.4 10.4 0.0 2.2 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.6 CDJ63189.1 - 1.8 9.0 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 1 0 AAA domain Suf PF05843.14 CDJ63189.1 - 3.7 7.5 10.1 6.3 6.7 10.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ABC_tran PF00005.27 CDJ63190.1 - 1.4e-13 51.6 1.5 1.9e-11 44.6 1.5 2.3 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ63190.1 - 3.4e-08 33.2 0.4 4.5e-08 32.8 0.4 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SpoIIP PF07454.11 CDJ63190.1 - 0.0083 15.6 1.0 0.0092 15.5 1.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) PAT1 PF09770.9 CDJ63190.1 - 0.0094 14.3 8.3 0.0094 14.3 8.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SbcCD_C PF13558.6 CDJ63190.1 - 0.015 15.5 0.6 0.21 11.8 0.6 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Presenilin PF01080.17 CDJ63190.1 - 0.017 13.9 5.4 0.021 13.6 5.4 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 CDJ63190.1 - 0.021 15.0 1.6 0.022 14.9 1.6 1.2 1 0 0 1 1 1 0 DDHD domain GREB1 PF15782.5 CDJ63190.1 - 0.033 11.3 3.0 0.034 11.3 3.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CDJ63190.1 - 0.085 12.8 20.0 0.11 12.4 20.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPL5 PF18168.1 CDJ63190.1 - 0.09 12.1 1.8 0.13 11.5 1.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Folate_carrier PF01770.18 CDJ63190.1 - 0.11 11.1 1.4 0.13 11.0 1.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier Pex14_N PF04695.13 CDJ63190.1 - 0.43 11.2 11.8 0.68 10.6 11.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Asparaginase_2 PF01112.18 CDJ63190.1 - 0.5 9.3 4.9 0.69 8.9 4.0 1.6 2 0 0 2 2 2 0 Asparaginase CDC45 PF02724.14 CDJ63190.1 - 0.55 8.5 8.6 1.8 6.7 8.6 1.7 2 0 0 2 2 2 0 CDC45-like protein NPR3 PF03666.13 CDJ63190.1 - 0.66 8.7 7.9 0.91 8.2 7.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MCM_bind PF09739.9 CDJ63190.1 - 0.82 8.0 11.0 1.2 7.5 11.0 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Neur_chan_memb PF02932.16 CDJ63190.1 - 0.82 9.7 5.6 1.3 9.1 5.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ63190.1 - 0.94 9.2 6.2 0.67 9.7 4.8 1.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain ALMT PF11744.8 CDJ63190.1 - 1 8.1 3.7 1.3 7.8 3.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Suf PF05843.14 CDJ63190.1 - 1.8 8.5 9.7 2.7 7.9 9.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CobT PF06213.12 CDJ63190.1 - 1.9 7.8 16.3 3 7.2 16.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4746 PF15928.5 CDJ63190.1 - 3.5 7.0 7.2 4.8 6.5 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 CDJ63190.1 - 3.8 7.2 11.5 5.5 6.7 11.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UPF0560 PF10577.9 CDJ63190.1 - 3.9 5.8 14.0 5.2 5.5 14.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Paf1 PF03985.13 CDJ63190.1 - 4.7 6.1 13.5 6.6 5.6 13.5 1.1 1 0 0 1 1 1 0 Paf1 DUF2828 PF11443.8 CDJ63190.1 - 4.9 5.1 9.0 6.2 4.8 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) eIF-3_zeta PF05091.12 CDJ63190.1 - 6.3 5.7 14.5 8.1 5.3 14.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.7 CDJ63190.1 - 9.8 4.2 8.7 12 3.8 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SR-25 PF10500.9 CDJ63191.1 - 4.9 6.7 13.1 5.8 6.5 13.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CDJ63191.1 - 9.5 4.4 10.0 8.8 4.5 10.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UDG PF03167.19 CDJ63192.1 - 1.5e-16 60.8 0.0 2.5e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Mitofilin PF09731.9 CDJ63192.1 - 1.2e-05 24.4 16.2 1.5e-05 24.1 16.2 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF4647 PF15504.6 CDJ63192.1 - 0.016 14.4 6.5 0.021 13.9 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) MMR1 PF08505.10 CDJ63192.1 - 2 8.7 13.3 3 8.1 13.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Ndc1_Nup PF09531.10 CDJ63192.1 - 2.9 6.5 13.0 4.1 6.0 13.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IER PF05760.12 CDJ63192.1 - 6.6 6.9 19.7 9.1 6.5 19.7 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) Macoilin PF09726.9 CDJ63192.1 - 8.8 4.8 11.1 12 4.3 11.1 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CDJ63193.1 - 0.0015 17.4 10.3 0.0018 17.2 10.3 1.1 1 0 0 1 1 1 1 Presenilin NPR3 PF03666.13 CDJ63193.1 - 0.0016 17.4 7.4 0.0019 17.1 7.4 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF5427 PF10310.9 CDJ63193.1 - 0.019 13.9 12.2 0.023 13.7 12.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SOBP PF15279.6 CDJ63193.1 - 0.025 15.2 8.2 0.03 14.9 8.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein BAF1_ABF1 PF04684.13 CDJ63193.1 - 0.046 12.8 15.3 0.057 12.5 15.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mem_trans PF03547.18 CDJ63193.1 - 0.065 11.6 2.2 0.072 11.5 2.2 1.1 1 0 0 1 1 1 0 Membrane transport protein Neur_chan_memb PF02932.16 CDJ63193.1 - 0.1 12.6 2.4 0.13 12.3 2.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CDJ63193.1 - 0.12 11.6 4.8 0.17 11.1 4.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 CDJ63193.1 - 0.14 11.0 19.0 0.17 10.7 19.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 CDJ63193.1 - 0.14 10.5 13.0 0.17 10.2 13.0 1.1 1 0 0 1 1 1 0 Menin Ndc1_Nup PF09531.10 CDJ63193.1 - 0.16 10.6 10.3 0.2 10.3 10.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pneumo_att_G PF05539.11 CDJ63193.1 - 0.18 11.3 13.1 0.23 11.0 13.1 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SOG2 PF10428.9 CDJ63193.1 - 0.22 10.7 21.4 0.28 10.3 21.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1501 PF07394.12 CDJ63193.1 - 0.22 10.5 7.1 0.28 10.2 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Suf PF05843.14 CDJ63193.1 - 0.26 11.2 9.9 0.39 10.7 9.9 1.3 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4551 PF15087.6 CDJ63193.1 - 0.3 9.9 10.0 0.34 9.7 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 CDJ63193.1 - 0.39 8.9 14.3 0.49 8.6 14.3 1.0 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ63193.1 - 0.5 9.3 8.2 0.59 9.1 8.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NAM-associated PF14303.6 CDJ63193.1 - 0.6 10.8 15.6 0.77 10.5 15.6 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SID-1_RNA_chan PF13965.6 CDJ63193.1 - 0.75 8.1 3.5 0.95 7.8 3.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Membralin PF09746.9 CDJ63193.1 - 0.8 8.7 3.3 1.1 8.3 3.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein PA26 PF04636.13 CDJ63193.1 - 0.97 8.3 4.4 1.1 8.1 4.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.7 CDJ63193.1 - 1.1 7.3 13.2 1.4 7.0 13.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4614 PF15391.6 CDJ63193.1 - 1.2 9.1 25.5 1.7 8.6 25.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Raftlin PF15250.6 CDJ63193.1 - 1.3 7.7 9.2 1.5 7.5 9.2 1.0 1 0 0 1 1 1 0 Raftlin Velvet PF11754.8 CDJ63193.1 - 1.5 8.7 16.2 4.5 7.2 16.2 1.6 1 1 0 1 1 1 0 Velvet factor ALMT PF11744.8 CDJ63193.1 - 2.1 7.1 9.9 2.6 6.8 9.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PNISR PF15996.5 CDJ63193.1 - 2.2 8.5 11.3 2.7 8.2 11.3 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Macoilin PF09726.9 CDJ63193.1 - 2.3 6.7 19.8 2.8 6.4 19.8 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CDJ63193.1 - 2.4 5.2 12.3 2.8 5.0 12.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3807 PF12720.7 CDJ63193.1 - 2.8 8.2 16.4 3.7 7.8 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) TraG_N PF07916.11 CDJ63193.1 - 4.2 6.1 10.6 6.5 5.5 10.6 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region MAP65_ASE1 PF03999.12 CDJ63193.1 - 5.3 5.6 17.0 6.3 5.4 17.0 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4554 PF15091.6 CDJ63193.1 - 6.1 5.6 12.1 7.9 5.2 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) SRP-alpha_N PF04086.13 CDJ63193.1 - 6.9 6.5 19.9 9.1 6.1 19.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Gti1_Pac2 PF09729.9 CDJ63193.1 - 9 6.3 17.9 29 4.7 18.0 1.7 1 1 0 1 1 1 0 Gti1/Pac2 family HATPase_c PF02518.26 CDJ63194.1 - 0.00038 21.0 0.0 0.0017 18.8 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SAS-6_N PF16531.5 CDJ63195.1 - 3.4e-11 43.6 0.0 3.4e-11 43.6 0.0 5.4 5 2 0 5 5 5 1 Centriolar protein SAS N-terminal DUF3337 PF11816.8 CDJ63196.1 - 0.1 12.4 1.0 0.24 11.3 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Hydrolase PF00702.26 CDJ63197.1 - 1.6e-10 41.6 19.0 1.8e-06 28.4 0.7 5.2 4 1 0 4 4 4 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ63197.1 - 1.2e-08 34.6 0.0 2e-07 30.7 0.0 3.1 1 1 0 1 1 1 1 E1-E2 ATPase PIN_4 PF13638.6 CDJ63197.1 - 0.17 12.2 0.4 0.7 10.2 0.2 2.1 2 0 0 2 2 2 0 PIN domain HAD PF12710.7 CDJ63197.1 - 5.8 7.3 7.2 3.2 8.1 0.0 3.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase OppC_N PF12911.7 CDJ63197.1 - 7.5 6.6 6.4 5.4 7.1 0.1 3.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C EF-hand_7 PF13499.6 CDJ63198.1 - 6.5e-31 106.6 19.8 2.8e-09 37.3 0.3 4.0 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 CDJ63198.1 - 2.5e-29 98.6 14.8 1.1e-05 24.7 0.1 6.6 7 0 0 7 7 7 5 EF hand EF-hand_5 PF13202.6 CDJ63198.1 - 5.5e-27 92.0 14.8 2.9e-05 23.3 0.2 6.6 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 CDJ63198.1 - 4.4e-24 82.3 9.4 3.2e-05 23.5 0.1 6.7 6 1 0 6 6 6 5 EF-hand domain EF-hand_8 PF13833.6 CDJ63198.1 - 1e-13 50.9 10.7 0.035 14.0 0.1 5.9 6 0 0 6 6 6 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ63198.1 - 5.1e-11 42.9 4.8 0.011 16.0 0.1 3.3 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Unstab_antitox PF09720.10 CDJ63198.1 - 0.0011 18.9 0.3 0.0011 18.9 0.3 2.6 4 0 0 4 4 4 1 Putative addiction module component Dockerin_1 PF00404.18 CDJ63198.1 - 0.0043 17.2 3.9 1.3 9.3 0.5 3.8 2 2 2 4 4 4 1 Dockerin type I domain EF-hand_4 PF12763.7 CDJ63198.1 - 0.1 12.6 7.5 7.6 6.6 0.8 4.2 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand O-FucT PF10250.9 CDJ63198.1 - 0.11 12.2 0.2 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Fes1 PF08609.10 CDJ63198.1 - 0.51 11.3 8.6 1.9 9.4 1.1 3.2 2 1 1 3 3 3 0 Nucleotide exchange factor Fes1 DUF3349 PF11829.8 CDJ63198.1 - 0.83 10.5 4.2 6.6 7.6 0.0 2.9 3 1 1 4 4 3 0 Protein of unknown function (DUF3349) Mst1_SARAH PF11629.8 CDJ63198.1 - 1.6 8.9 6.2 5.6 7.1 0.2 3.6 4 0 0 4 4 4 0 C terminal SARAH domain of Mst1 NPA PF16469.5 CDJ63198.1 - 3.7 8.2 7.2 2 9.0 2.6 2.4 1 1 1 2 2 2 0 Nematode polyprotein allergen ABA-1 ABC2_membrane_2 PF12679.7 CDJ63200.1 - 0.092 12.0 3.9 1.3 8.2 3.9 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein Dapper PF15268.6 CDJ63200.1 - 2.7 6.7 35.4 3.3 6.4 35.4 1.1 1 0 0 1 1 1 0 Dapper SPX PF03105.19 CDJ63200.1 - 6.6 6.5 27.3 44 3.8 0.0 2.0 2 0 0 2 2 2 0 SPX domain Apolipoprotein PF01442.18 CDJ63201.1 - 9.4e-09 35.4 15.9 2.6e-08 33.9 15.9 1.8 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain PAP2_C PF14360.6 CDJ63201.1 - 2e-06 28.2 13.8 0.00012 22.5 3.8 2.6 2 0 0 2 2 2 2 PAP2 superfamily C-terminal PAP2 PF01569.21 CDJ63201.1 - 0.0044 16.8 2.3 0.0044 16.8 2.3 2.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CDJ63201.1 - 0.049 13.3 3.8 0.14 11.8 3.8 1.8 1 0 0 1 1 1 0 PAP2 superfamily Phage_Mu_Gam PF07352.12 CDJ63201.1 - 0.33 10.9 11.7 3.3 7.6 3.9 2.7 1 1 2 3 3 3 0 Bacteriophage Mu Gam like protein Exonuc_VII_L PF02601.15 CDJ63201.1 - 2.4 7.6 14.0 4.3 6.8 14.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TSNAXIP1_N PF15739.5 CDJ63201.1 - 2.8 8.3 16.1 8 6.9 3.1 3.2 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus VitK2_biosynth PF02621.14 CDJ63201.1 - 3.9 6.9 4.9 6.5 6.2 0.2 2.4 1 1 1 2 2 2 0 Menaquinone biosynthesis FAM184 PF15665.5 CDJ63201.1 - 6.8 6.4 15.3 42 3.8 5.2 2.2 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B ApoLp-III PF07464.11 CDJ63201.1 - 8.7 6.4 11.7 25 4.9 7.6 2.0 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) RNA_POL_M_15KD PF02150.16 CDJ63202.1 - 1.2e-07 31.4 8.9 3.2e-07 30.1 6.1 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CDJ63202.1 - 1.8e-07 30.9 0.1 1.8e-07 30.9 0.1 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-RRN7 PF11781.8 CDJ63202.1 - 0.0087 15.7 3.8 1.4 8.7 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PhnA_Zn_Ribbon PF08274.12 CDJ63202.1 - 0.0096 15.9 2.4 26 4.9 0.2 3.8 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Ogr_Delta PF04606.12 CDJ63202.1 - 0.029 14.4 2.6 0.13 12.3 0.3 2.8 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger Lar_restr_allev PF14354.6 CDJ63202.1 - 0.055 13.9 0.5 0.055 13.9 0.5 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar CpXC PF14353.6 CDJ63202.1 - 0.097 12.7 0.1 0.097 12.7 0.1 2.5 2 1 1 3 3 3 0 CpXC protein zinc_ribbon_10 PF10058.9 CDJ63202.1 - 0.098 12.4 3.1 11 5.9 0.4 3.0 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Nudc_N PF14050.6 CDJ63202.1 - 0.11 12.5 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. zf-ISL3 PF14690.6 CDJ63202.1 - 0.12 13.1 6.4 1.4 9.7 0.1 2.9 2 1 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 IBR PF01485.21 CDJ63202.1 - 0.14 12.4 5.9 1.4 9.2 0.5 3.1 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain PHD PF00628.29 CDJ63202.1 - 0.15 12.0 7.7 6.6 6.7 0.2 3.0 2 1 0 2 2 2 0 PHD-finger Zn_Tnp_IS1595 PF12760.7 CDJ63202.1 - 0.18 11.8 5.4 3.1 7.9 0.3 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-ACC PF17848.1 CDJ63202.1 - 0.21 11.7 8.6 11 6.2 0.2 4.4 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain Rubredoxin PF00301.20 CDJ63202.1 - 0.21 11.6 4.2 0.42 10.7 0.2 3.0 3 0 0 3 3 3 0 Rubredoxin zf_UBZ PF18439.1 CDJ63202.1 - 0.32 10.6 6.2 6.4 6.5 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger A2L_zn_ribbon PF08792.10 CDJ63202.1 - 0.44 10.3 3.5 3.9 7.3 0.2 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-RING_7 PF02591.15 CDJ63202.1 - 0.55 10.5 3.7 21 5.4 0.0 3.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 CDJ63202.1 - 0.74 9.3 9.0 4 7.0 0.1 3.2 4 0 0 4 4 4 0 zinc-ribbon domain Nudix_N_2 PF14803.6 CDJ63202.1 - 1 9.4 8.1 11 6.0 1.0 3.5 3 0 0 3 3 3 0 Nudix N-terminal DZR PF12773.7 CDJ63202.1 - 1.1 9.4 10.6 29 4.8 0.7 2.8 1 1 1 2 2 2 0 Double zinc ribbon zf-IS66 PF13005.7 CDJ63202.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.2 3 1 1 4 4 4 0 zinc-finger binding domain of transposase IS66 zinc_ribbon_9 PF14369.6 CDJ63202.1 - 1.3 9.4 7.5 2.2 8.6 0.3 3.0 2 1 1 3 3 3 0 zinc-ribbon Zn_ribbon_recom PF13408.6 CDJ63202.1 - 1.4 9.5 5.5 0.72 10.4 0.2 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C4_Topoisom PF01396.19 CDJ63202.1 - 3.5 7.5 7.7 9.3 6.1 2.0 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-Mss51 PF13824.6 CDJ63202.1 - 4.9 7.3 5.5 23 5.2 0.3 2.6 3 0 0 3 3 2 0 Zinc-finger of mitochondrial splicing suppressor 51 TraT PF05818.12 CDJ63204.1 - 4 7.1 6.6 3 7.5 5.4 1.4 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Presenilin PF01080.17 CDJ63205.1 - 0.017 14.0 5.5 0.028 13.2 5.5 1.5 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ63205.1 - 0.96 8.4 5.6 1.2 8.0 5.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ63205.1 - 1.7 8.2 12.0 3.2 7.2 12.0 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Endostatin PF06482.11 CDJ63205.1 - 3.3 7.1 10.3 6.3 6.2 10.3 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin GET2 PF08690.10 CDJ63205.1 - 5.3 6.6 11.1 11 5.6 11.1 1.6 1 0 0 1 1 1 0 GET complex subunit GET2 Neur_chan_memb PF02932.16 CDJ63205.1 - 5.9 6.9 9.6 15 5.6 9.4 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.9 CDJ63206.1 - 0.011 15.3 15.0 0.011 15.3 15.0 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Tau95_N PF17682.1 CDJ63206.1 - 1.3 9.3 6.7 3.1 8.0 2.4 2.5 2 0 0 2 2 2 0 Tau95 Triple barrel domain Mt_ATP-synt_D PF05873.12 CDJ63207.1 - 0.0031 17.4 0.4 0.0031 17.4 0.4 1.8 2 0 0 2 2 2 1 ATP synthase D chain, mitochondrial (ATP5H) SUIM_assoc PF16619.5 CDJ63207.1 - 0.098 12.7 9.5 0.13 12.3 6.2 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4667 PF15700.5 CDJ63207.1 - 0.31 11.1 14.0 0.95 9.5 14.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ63207.1 - 2.9 7.4 11.7 1.6 8.3 9.3 1.8 2 0 0 2 2 2 0 Spt20 family MCM PF00493.23 CDJ63209.1 - 2.9e-35 121.4 3.2 3.8e-35 121.0 3.2 1.1 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 CDJ63209.1 - 1.4e-06 27.9 0.9 2.1e-06 27.3 0.9 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ63209.1 - 0.009 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF1180 PF06679.12 CDJ63209.1 - 0.022 15.2 0.5 0.045 14.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MinC_C PF03775.16 CDJ63209.1 - 0.1 12.6 0.3 0.17 11.9 0.3 1.3 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain Brix PF04427.18 CDJ63211.1 - 0.0021 18.2 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain Shadoo PF14999.6 CDJ63211.1 - 1.5 8.9 13.4 2.8 8.0 1.8 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Ephrin_rec_like PF07699.13 CDJ63213.1 - 8.4e-16 57.5 33.9 1e-06 28.4 2.3 5.2 4 1 1 5 5 5 4 Putative ephrin-receptor like RANK_CRD_2 PF18278.1 CDJ63213.1 - 0.049 13.8 8.8 0.35 11.1 1.3 3.4 3 0 0 3 3 3 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 RVP_2 PF08284.11 CDJ63214.1 - 6.2e-12 45.4 0.0 9.7e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ63214.1 - 1.9e-10 41.2 0.0 3.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ63214.1 - 3.6e-10 40.3 0.0 7.4e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ63214.1 - 5.1e-05 23.1 0.0 8.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ63214.1 - 0.00056 20.2 0.0 0.0018 18.5 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease AP2 PF00847.20 CDJ63216.1 - 2.3e-07 30.9 0.5 2.3e-07 30.9 0.5 5.6 4 0 0 4 4 4 1 AP2 domain Metallophos PF00149.28 CDJ63217.1 - 1e-41 143.7 0.1 1.3e-41 143.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ63217.1 - 7.5e-22 77.5 0.5 1.8e-21 76.3 0.2 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Nop PF01798.18 CDJ63218.1 - 2e-68 230.3 4.3 2e-67 227.0 0.1 2.8 2 1 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CDJ63218.1 - 2.3e-13 50.3 0.1 2.3e-13 50.3 0.1 2.6 3 0 0 3 3 3 1 NOP5NT (NUC127) domain AAA_lid_9 PF17871.1 CDJ63218.1 - 0.011 15.6 8.8 0.011 15.6 8.8 2.3 1 1 1 2 2 2 0 AAA lid domain RNA_polI_A34 PF08208.11 CDJ63218.1 - 1.3 9.0 23.0 2.5 8.1 23.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Cdh1_DBD_1 PF18196.1 CDJ63218.1 - 1.9 8.8 13.7 6.3 7.1 13.6 2.0 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 Asp-B-Hydro_N PF05279.11 CDJ63218.1 - 6.1 6.8 20.3 10 6.1 20.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MFS_1 PF07690.16 CDJ63219.1 - 2.3e-25 89.3 35.6 2.3e-25 89.3 35.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ63219.1 - 2.7e-14 52.9 28.2 8.7e-14 51.2 28.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 CDJ63219.1 - 2.2e-09 36.2 24.5 7.7e-08 31.1 7.9 3.1 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Nuf2 PF03800.14 CDJ63222.1 - 0.0043 17.2 1.9 0.06 13.5 0.0 2.3 2 0 0 2 2 2 1 Nuf2 family Endonuc-dimeris PF09124.10 CDJ63222.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation Exonuc_VII_L PF02601.15 CDJ63222.1 - 9.4 5.7 20.9 0.12 11.9 2.3 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA_23 PF13476.6 CDJ63223.1 - 1.6 9.2 23.5 0.84 10.1 11.7 2.5 2 0 0 2 2 2 0 AAA domain Sin_N PF04801.13 CDJ63223.1 - 2.8 7.1 34.4 0.045 13.0 1.0 2.4 2 0 0 2 2 2 0 Sin-like protein conserved region GREB1 PF15782.5 CDJ63223.1 - 8.3 3.4 39.4 2.2 5.3 25.8 2.3 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer SR-25 PF10500.9 CDJ63224.1 - 0.002 17.8 6.6 0.002 17.8 6.6 8.5 5 3 3 8 8 8 2 Nuclear RNA-splicing-associated protein SARAF PF06682.12 CDJ63224.1 - 0.0031 17.2 7.3 0.0031 17.2 7.3 6.5 5 1 1 6 6 6 1 SOCE-associated regulatory factor of calcium homoeostasis HTH_Tnp_Tc3_2 PF01498.18 CDJ63225.1 - 0.038 14.2 0.3 0.09 13.0 0.3 1.6 1 0 0 1 1 1 0 Transposase SUIM_assoc PF16619.5 CDJ63225.1 - 1.9 8.6 54.6 0.17 12.0 0.2 5.9 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Thioredoxin PF00085.20 CDJ63226.1 - 1.1e-14 54.3 0.0 8.7e-13 48.2 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin DnaJ PF00226.31 CDJ63226.1 - 1.2e-13 50.9 1.4 3e-13 49.7 1.4 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_6 PF13848.6 CDJ63226.1 - 2.4e-08 34.1 0.2 0.0003 20.8 0.1 3.2 3 1 1 4 4 4 2 Thioredoxin-like domain SUIM_assoc PF16619.5 CDJ63226.1 - 0.00098 19.1 1.0 0.0022 18.0 1.0 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Sulfatase_C PF14707.6 CDJ63226.1 - 0.32 11.8 2.5 0.37 11.5 0.1 2.2 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase Neur_chan_memb PF02932.16 CDJ63228.1 - 9e-05 22.6 1.4 0.00011 22.3 1.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region LPG_synthase_TM PF03706.13 CDJ63228.1 - 0.043 13.4 0.5 0.053 13.0 0.5 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region LEA_3 PF03242.13 CDJ63228.1 - 0.64 10.8 0.1 0.64 10.8 0.1 2.3 2 1 0 2 2 2 0 Late embryogenesis abundant protein Cas_Csy4 PF09618.10 CDJ63228.1 - 9.7 6.3 14.4 1.1 9.4 0.6 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) Band_7 PF01145.25 CDJ63229.1 - 1e-24 87.5 0.3 1.5e-24 87.0 0.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CDJ63229.1 - 0.00013 21.1 1.2 0.00017 20.8 1.2 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 CDJ63229.1 - 0.065 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family WHAMM-JMY_N PF15920.5 CDJ63229.1 - 0.19 11.6 0.5 0.38 10.7 0.5 1.4 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated PAP2 PF01569.21 CDJ63230.1 - 3.6e-21 75.3 1.2 3.6e-21 75.3 1.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CDJ63230.1 - 0.018 15.5 0.1 0.018 15.5 0.1 2.6 3 0 0 3 3 3 0 PAP2 superfamily C-terminal DDE_Tnp_1_4 PF13701.6 CDJ63230.1 - 0.093 11.0 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 SUIM_assoc PF16619.5 CDJ63231.1 - 1.5e-05 25.0 9.0 0.0026 17.8 3.6 2.5 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ63231.1 - 0.13 11.1 5.7 0.064 12.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ63231.1 - 0.18 12.4 13.6 0.26 12.0 2.5 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ63231.1 - 4.5 6.8 18.4 0.73 9.4 8.2 2.4 2 0 0 2 2 2 0 Spt20 family Band_3_cyto PF07565.13 CDJ63233.1 - 0.14 12.0 0.1 0.14 12.0 0.1 8.1 4 2 1 5 5 5 0 Band 3 cytoplasmic domain SRP72 PF08492.12 CDJ63234.1 - 1.1e-11 45.0 10.7 2.3e-11 43.9 10.7 1.6 1 0 0 1 1 1 1 SRP72 RNA-binding domain Ribosomal_60s PF00428.19 CDJ63234.1 - 0.0011 19.5 6.3 0.0011 19.5 6.3 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein SRP_TPR_like PF17004.5 CDJ63236.1 - 0.0085 16.1 2.1 0.072 13.1 1.9 2.5 1 1 0 1 1 1 1 Putative TPR-like repeat ANAPC3 PF12895.7 CDJ63236.1 - 0.025 14.8 8.1 0.63 10.3 1.1 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CDJ63236.1 - 0.078 13.1 18.9 1.4 9.2 1.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ63236.1 - 1.7 8.9 13.3 1.9 8.7 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1645 PF07816.11 CDJ63237.1 - 0.012 16.1 1.9 0.012 16.1 1.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) MSA-2c PF12238.8 CDJ63237.1 - 0.16 11.9 0.8 0.29 11.1 0.8 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Ribosomal_60s PF00428.19 CDJ63237.1 - 0.95 10.1 30.5 0.47 11.1 4.7 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein CCSAP PF15748.5 CDJ63237.1 - 1.7 8.8 11.7 2.8 8.0 2.4 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SQHop_cyclase_C PF13243.6 CDJ63237.1 - 2.3 7.2 6.3 1.3 8.0 4.4 1.5 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain SPX PF03105.19 CDJ63237.1 - 6.5 6.6 8.3 34 4.2 8.3 1.8 1 1 0 1 1 1 0 SPX domain RVP_2 PF08284.11 CDJ63238.1 - 4.6e-12 45.9 0.0 6.9e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ63238.1 - 5.8e-10 39.7 0.0 1.5e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ63238.1 - 2.4e-08 34.4 0.0 5e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ63238.1 - 0.012 15.9 0.0 0.061 13.6 0.0 2.1 2 1 0 2 2 2 0 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ63238.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease MRJP PF03022.16 CDJ63240.1 - 0.78 9.0 8.4 3.7 6.8 8.4 2.2 1 0 0 1 1 1 0 Major royal jelly protein Sec23_trunk PF04811.15 CDJ63240.1 - 4.3 6.8 11.6 1 8.8 5.3 3.0 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain SUIM_assoc PF16619.5 CDJ63242.1 - 0.0012 18.8 0.6 0.0012 18.8 0.6 3.7 5 1 0 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 DUF4667 PF15700.5 CDJ63242.1 - 0.016 15.3 2.5 0.016 15.3 2.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) Clathrin PF00637.20 CDJ63242.1 - 0.049 13.5 10.4 0.12 12.3 0.4 3.9 4 0 0 4 4 4 0 Region in Clathrin and VPS CCDC24 PF15669.5 CDJ63242.1 - 0.81 9.5 13.1 0.26 11.1 4.4 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Ctr PF04145.15 CDJ63242.1 - 5.5 7.6 5.2 6.7 7.3 0.5 2.6 2 0 0 2 2 2 0 Ctr copper transporter family DUF755 PF05501.11 CDJ63242.1 - 5.5 7.3 33.4 0.023 15.0 17.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Ribosomal_60s PF00428.19 CDJ63243.1 - 0.024 15.2 10.0 0.042 14.4 10.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ig_mannosidase PF17753.1 CDJ63243.1 - 0.067 13.0 0.1 0.17 11.6 0.1 1.8 1 1 0 1 1 1 0 Ig-fold domain Dapper PF15268.6 CDJ63243.1 - 5.8 5.6 36.3 6.4 5.5 36.3 1.1 1 0 0 1 1 1 0 Dapper PRCC PF10253.9 CDJ63244.1 - 0.016 16.0 23.4 0.016 16.0 23.4 3.6 4 0 0 4 4 4 0 Mitotic checkpoint regulator, MAD2B-interacting PIG-U PF06728.13 CDJ63244.1 - 0.13 11.2 0.3 0.33 10.0 0.0 1.9 2 0 0 2 2 2 0 GPI transamidase subunit PIG-U Zip PF02535.22 CDJ63244.1 - 2.1 7.5 24.9 0.27 10.4 1.9 2.8 2 0 0 2 2 2 0 ZIP Zinc transporter DUF755 PF05501.11 CDJ63246.1 - 0.0043 17.3 3.5 0.0043 17.3 3.5 3.6 3 1 1 4 4 4 1 Domain of unknown function (DUF755) SurE PF01975.17 CDJ63246.1 - 0.32 10.8 5.0 0.22 11.3 1.8 2.0 1 1 1 2 2 2 0 Survival protein SurE RskA PF10099.9 CDJ63246.1 - 0.69 10.2 43.9 0.23 11.7 9.4 3.6 1 1 1 2 2 2 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ63246.1 - 0.9 9.1 12.0 0.15 11.7 5.1 2.3 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.19 CDJ63246.1 - 8.4 7.1 25.6 0.73 10.5 4.0 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Conotoxin PF02950.17 CDJ63247.1 - 0.31 12.1 15.3 1 10.4 4.5 2.5 2 0 0 2 2 2 0 Conotoxin Peptidase_S46 PF10459.9 CDJ63247.1 - 0.5 8.9 9.2 0.59 8.7 9.2 1.1 1 0 0 1 1 1 0 Peptidase S46 Tn7_Tnp_TnsA_C PF08721.11 CDJ63247.1 - 0.89 10.2 3.6 1.8 9.2 1.6 2.1 2 0 0 2 2 2 0 TnsA endonuclease C terminal Virul_fac_BrkB PF03631.15 CDJ63247.1 - 1.3 8.6 3.2 1.9 8.0 3.2 1.3 1 0 0 1 1 1 0 Virulence factor BrkB GvpL_GvpF PF06386.11 CDJ63247.1 - 4.2 7.2 12.9 1.2 9.0 5.8 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF4338 PF14236.6 CDJ63247.1 - 7.3 5.8 8.6 0.39 9.9 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4338) DUF755 PF05501.11 CDJ63247.1 - 9.5 6.5 31.0 0.77 10.0 10.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) MCM_OB PF17207.3 CDJ63248.1 - 5.9e-08 32.6 0.0 5.9e-08 32.6 0.0 2.7 2 0 0 2 2 2 1 MCM OB domain MCM PF00493.23 CDJ63248.1 - 5.2e-07 29.0 0.4 5.2e-07 29.0 0.4 2.1 3 0 0 3 3 3 1 MCM P-loop domain RskA PF10099.9 CDJ63248.1 - 0.015 15.6 23.0 0.015 15.6 23.0 6.7 3 2 3 6 6 6 0 Anti-sigma-K factor rskA Choline_transpo PF04515.12 CDJ63248.1 - 2.2 7.4 6.7 4.5 6.4 6.7 1.5 1 0 0 1 1 1 0 Plasma-membrane choline transporter Roc PF08477.13 CDJ63248.1 - 4.3 7.6 5.0 0.85 9.8 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RskA PF10099.9 CDJ63249.1 - 1.9e-08 34.8 0.1 6.8e-06 26.5 0.0 12.8 3 2 6 11 11 11 4 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ63249.1 - 0.00032 20.4 10.2 0.00032 20.4 10.2 7.7 7 1 1 8 8 8 3 Nuclear RNA-splicing-associated protein Cytochrom_B_N_2 PF13631.6 CDJ63249.1 - 0.11 12.4 0.3 3 7.8 0.0 3.2 3 0 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB PAP2 PF01569.21 CDJ63249.1 - 5 6.9 9.7 2.4 7.9 0.4 4.8 4 1 0 4 4 4 0 PAP2 superfamily SUIM_assoc PF16619.5 CDJ63250.1 - 0.0043 17.1 1.0 0.0043 17.1 1.0 2.5 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF4131 PF13567.6 CDJ63250.1 - 0.079 12.6 15.8 0.59 9.8 10.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2722 PF10846.8 CDJ63250.1 - 3.1 6.7 6.4 0.92 8.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Paralemmin PF03285.15 CDJ63250.1 - 7.8 6.0 7.1 0.25 10.9 0.8 1.7 2 0 0 2 2 2 0 Paralemmin zf-RanBP PF00641.18 CDJ63251.1 - 9.5e-05 21.6 5.4 0.00026 20.2 5.4 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SR-25 PF10500.9 CDJ63251.1 - 0.0008 19.1 2.3 0.0008 19.1 2.3 6.8 5 1 1 6 6 6 2 Nuclear RNA-splicing-associated protein Trp_oprn_chp PF09534.10 CDJ63251.1 - 0.0035 17.2 4.5 0.0035 17.2 4.5 4.6 4 1 0 4 4 4 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SR-25 PF10500.9 CDJ63252.1 - 0.012 15.2 11.7 0.012 15.2 11.7 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ63252.1 - 0.13 13.0 9.3 0.14 12.9 9.3 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF3446 PF11928.8 CDJ63252.1 - 0.25 11.7 13.2 0.26 11.6 13.2 1.1 1 0 0 1 1 1 0 Early growth response N-terminal domain RskA PF10099.9 CDJ63253.1 - 2.9e-08 34.2 2.9 5.4e-08 33.3 2.4 1.6 1 1 0 1 1 1 1 Anti-sigma-K factor rskA HMG_box PF00505.19 CDJ63253.1 - 8.1e-08 32.6 0.7 8.1e-08 32.6 0.7 2.2 1 1 1 2 2 2 1 HMG (high mobility group) box Macoilin PF09726.9 CDJ63253.1 - 5.5e-06 25.2 21.5 6.7e-06 25.0 21.5 1.2 1 0 0 1 1 1 1 Macoilin family CBFD_NFYB_HMF PF00808.23 CDJ63253.1 - 0.00014 22.0 0.0 0.00035 20.8 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2722 PF10846.8 CDJ63253.1 - 0.0002 20.5 10.5 0.0002 20.5 10.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) HMG_box_2 PF09011.10 CDJ63253.1 - 0.0028 18.2 11.8 0.039 14.6 11.8 2.3 1 1 0 1 1 1 1 HMG-box domain EPL1 PF10513.9 CDJ63253.1 - 0.0066 16.8 12.1 0.11 12.9 4.7 2.4 2 0 0 2 2 2 2 Enhancer of polycomb-like MRP-L46 PF11788.8 CDJ63253.1 - 0.15 12.8 12.8 0.34 11.6 12.8 1.6 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Zip PF02535.22 CDJ63253.1 - 0.5 9.5 11.6 1.9 7.6 2.5 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Exonuc_VII_L PF02601.15 CDJ63253.1 - 0.55 9.8 11.6 0.79 9.2 11.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pex14_N PF04695.13 CDJ63253.1 - 0.77 10.4 25.5 0.83 10.3 10.0 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CDJ63253.1 - 0.79 8.4 22.6 0.26 10.0 6.3 2.2 2 0 0 2 2 2 0 Presenilin DUF4746 PF15928.5 CDJ63253.1 - 0.99 8.8 11.3 2.5 7.4 11.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) FapA PF03961.13 CDJ63253.1 - 1.4 7.5 4.0 2 6.9 4.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A SLC12 PF03522.15 CDJ63253.1 - 1.5 7.8 14.1 1.3 8.0 5.3 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Band_3_cyto PF07565.13 CDJ63253.1 - 1.9 8.2 13.4 0.44 10.3 2.8 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Slu7 PF11708.8 CDJ63253.1 - 2.1 8.0 17.5 0.069 12.9 9.5 2.0 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor PNISR PF15996.5 CDJ63253.1 - 2.3 8.5 21.4 0.47 10.7 7.7 2.4 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR AUX_IAA PF02309.16 CDJ63253.1 - 2.8 7.7 15.5 1.7 8.4 2.7 2.3 2 0 0 2 2 2 0 AUX/IAA family LMBR1 PF04791.16 CDJ63253.1 - 3.6 6.4 8.4 5.9 5.7 8.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Gti1_Pac2 PF09729.9 CDJ63253.1 - 5.5 7.0 19.8 0.53 10.4 1.9 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family SpoIIP PF07454.11 CDJ63253.1 - 5.9 6.3 13.6 0.36 10.3 5.9 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Kinesin PF00225.23 CDJ63254.1 - 5.2e-39 134.1 0.7 7.3e-21 74.4 0.0 5.8 5 2 1 6 6 6 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ63254.1 - 9.6e-14 51.6 0.9 1.2e-11 44.8 0.5 3.7 4 0 0 4 4 4 2 Microtubule binding RskA PF10099.9 CDJ63254.1 - 5e-05 23.7 0.1 5e-05 23.7 0.1 10.7 2 1 6 10 10 10 1 Anti-sigma-K factor rskA Dehydrin PF00257.19 CDJ63254.1 - 0.016 15.8 0.6 0.016 15.8 0.6 15.7 8 5 3 13 13 13 0 Dehydrin DUF3552 PF12072.8 CDJ63256.1 - 0.029 13.8 0.2 0.054 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Peptidase_S28 PF05577.12 CDJ63257.1 - 1.2e-13 50.7 5.5 1.3e-09 37.4 0.0 3.1 1 1 2 3 3 3 2 Serine carboxypeptidase S28 DUF2722 PF10846.8 CDJ63257.1 - 0.0051 15.8 9.4 0.0067 15.4 9.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ63257.1 - 0.0052 15.6 7.9 0.0048 15.7 7.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4698 PF15769.5 CDJ63257.1 - 0.0067 15.5 2.9 0.01 14.9 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4698) ANAPC_CDC26 PF10471.9 CDJ63257.1 - 0.018 15.9 11.7 0.018 15.9 11.7 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Suf PF05843.14 CDJ63257.1 - 0.029 14.3 3.2 0.031 14.3 3.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF853 PF05872.12 CDJ63257.1 - 0.059 12.0 0.5 0.065 11.8 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Rsc14 PF08586.10 CDJ63257.1 - 0.12 13.2 1.3 0.23 12.3 1.3 1.5 1 1 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit UPF0560 PF10577.9 CDJ63257.1 - 0.19 10.2 3.3 0.21 10.1 3.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Presenilin PF01080.17 CDJ63257.1 - 0.35 9.6 0.6 0.32 9.7 0.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ63257.1 - 0.49 11.4 5.8 1.1 10.3 5.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Roughex PF06020.11 CDJ63257.1 - 1.3 8.0 5.8 1.6 7.8 5.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SAM_decarbox PF01536.16 CDJ63257.1 - 1.5 7.7 5.1 2 7.4 5.1 1.1 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase CDC13_N PF16853.5 CDJ63257.1 - 1.5 8.3 6.3 2.4 7.6 6.3 1.2 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus Spt20 PF12090.8 CDJ63257.1 - 2 8.0 23.6 0.14 11.7 18.6 1.5 2 0 0 2 2 2 0 Spt20 family DUF755 PF05501.11 CDJ63258.1 - 0.00023 21.4 22.5 0.00023 21.4 22.5 4.2 2 1 2 4 4 4 1 Domain of unknown function (DUF755) EPL1 PF10513.9 CDJ63258.1 - 0.063 13.7 0.2 0.063 13.7 0.2 3.3 3 1 0 3 3 3 0 Enhancer of polycomb-like O-antigen_lig PF13425.6 CDJ63258.1 - 0.11 11.3 8.5 0.026 13.3 3.9 1.9 2 0 0 2 2 2 0 O-antigen ligase like membrane protein NPR3 PF03666.13 CDJ63258.1 - 0.31 9.8 29.8 0.055 12.3 13.2 2.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Lin-8 PF03353.15 CDJ63258.1 - 1.5 8.3 47.6 0.25 10.9 21.4 2.6 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist DUF572 PF04502.13 CDJ63258.1 - 2.2 7.8 40.4 4.2 6.9 40.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) UPF0565 PF10561.9 CDJ63258.1 - 4.8 6.3 0.0 4.8 6.3 0.0 2.6 3 1 0 3 3 3 0 Uncharacterised protein family UPF0565 Macoilin PF09726.9 CDJ63258.1 - 5.5 5.4 45.0 0.8 8.2 8.9 2.1 2 0 0 2 2 2 0 Macoilin family CLN3 PF02487.17 CDJ63258.1 - 5.9 5.8 26.0 1.4 7.9 13.4 2.4 2 0 0 2 2 2 0 CLN3 protein SID-1_RNA_chan PF13965.6 CDJ63258.1 - 8.7 4.6 17.3 0.065 11.6 5.5 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 SR-25 PF10500.9 CDJ63259.1 - 5e-05 23.0 9.8 5e-05 23.0 9.8 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein IQCJ-SCHIP1 PF15157.6 CDJ63259.1 - 0.16 11.8 5.7 0.32 10.8 5.7 1.4 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif TFIIA PF03153.13 CDJ63259.1 - 0.98 9.3 22.9 2 8.3 8.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1635 PF07795.11 CDJ63259.1 - 1.6 8.5 15.3 0.54 10.1 6.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Secretin_N_2 PF07655.13 CDJ63259.1 - 6.8 7.3 17.1 0.15 12.6 7.4 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain V_ATPase_I PF01496.19 CDJ63260.1 - 0.012 13.6 10.0 0.016 13.1 10.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gly-zipper_OmpA PF13436.6 CDJ63260.1 - 0.014 15.2 18.7 93 2.9 18.7 2.9 1 1 0 1 1 1 0 Glycine-zipper domain DUF4834 PF16118.5 CDJ63260.1 - 0.067 14.2 17.5 0.15 13.0 12.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Serinc PF03348.15 CDJ63260.1 - 0.099 11.6 6.3 0.12 11.3 6.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 CDJ63260.1 - 0.16 10.7 18.6 0.23 10.2 18.6 1.2 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 CDJ63260.1 - 0.31 10.0 9.6 0.52 9.2 9.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MID_MedPIWI PF18296.1 CDJ63260.1 - 0.37 10.5 16.4 0.57 9.9 16.4 1.3 1 0 0 1 1 1 0 MID domain of medPIWI Gly-zipper_YMGG PF13441.6 CDJ63260.1 - 0.45 10.3 12.4 48 3.8 12.4 2.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper SLC12 PF03522.15 CDJ63260.1 - 0.63 9.0 13.4 0.83 8.6 13.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ63260.1 - 1 7.7 5.1 1.2 7.5 5.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF5523 PF17661.1 CDJ63260.1 - 1.1 8.9 22.0 1.6 8.4 22.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Rick_17kDa_Anti PF05433.15 CDJ63260.1 - 1.1 9.1 10.7 15 5.5 10.7 2.3 1 1 0 1 1 1 0 Glycine zipper 2TM domain ANAPC8 PF04049.13 CDJ63260.1 - 1.2 9.2 14.0 0.41 10.7 9.5 2.0 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 Neur_chan_memb PF02932.16 CDJ63260.1 - 2.2 8.2 13.3 3 7.8 13.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ureide_permease PF07168.11 CDJ63260.1 - 2.3 6.9 5.8 3.2 6.4 5.8 1.2 1 0 0 1 1 1 0 Ureide permease DUF3408 PF11888.8 CDJ63260.1 - 3.5 7.8 19.5 0.64 10.2 13.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Bacteriocin_IIc PF10439.9 CDJ63260.1 - 3.6 7.8 22.9 1.8e+04 -5.5 22.9 3.4 1 1 0 1 1 0 0 Bacteriocin class II with double-glycine leader peptide MLANA PF14991.6 CDJ63260.1 - 3.7 7.9 5.7 0.42 10.9 1.2 1.7 2 0 0 2 2 2 0 Protein melan-A HA2 PF04408.23 CDJ63260.1 - 5.3 7.4 8.6 11 6.3 6.6 2.1 2 0 0 2 2 2 0 Helicase associated domain (HA2) IMCp PF12314.8 CDJ63261.1 - 2.2e-13 50.3 58.0 1.7e-08 34.7 27.8 3.6 2 1 2 4 4 4 3 Inner membrane complex protein Gly-zipper_OmpA PF13436.6 CDJ63261.1 - 7.2 6.5 8.5 2.5 8.0 1.3 2.4 2 0 0 2 2 2 0 Glycine-zipper domain Thioredoxin PF00085.20 CDJ63262.1 - 7.5e-29 99.8 0.0 1.1e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ63262.1 - 2.8e-06 27.8 0.2 3.1e-05 24.4 0.2 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CDJ63262.1 - 3.5e-05 23.7 0.0 5.1e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.11 CDJ63262.1 - 0.002 18.1 0.0 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 CDJ63262.1 - 0.003 17.7 0.0 0.0073 16.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 CDJ63262.1 - 0.0039 17.5 0.0 0.035 14.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.6 CDJ63262.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CDJ63262.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 CDJ63262.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.6 CDJ63262.1 - 0.016 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin JAB PF01398.21 CDJ63263.1 - 7.1e-12 45.3 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CDJ63263.1 - 9.4e-10 38.9 0.0 1.6e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF2336 PF10098.9 CDJ63263.1 - 0.025 14.1 2.1 0.048 13.1 2.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) NID PF07292.13 CDJ63263.1 - 0.16 12.7 0.0 0.42 11.3 0.0 1.8 1 1 0 1 1 1 0 Nmi/IFP 35 domain (NID) DUF3923 PF13061.6 CDJ63264.1 - 0.37 10.9 0.9 0.58 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) Bacillus_HBL PF05791.11 CDJ63266.1 - 0.0026 17.6 7.0 0.0026 17.6 7.0 2.9 2 1 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) IL3 PF02059.15 CDJ63266.1 - 0.016 15.3 2.1 0.032 14.3 2.1 1.5 1 0 0 1 1 1 0 Interleukin-3 SYCE1 PF15233.6 CDJ63266.1 - 0.1 12.7 33.5 1.5 8.9 16.4 2.5 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Lebercilin PF15619.6 CDJ63266.1 - 0.12 12.0 35.7 0.19 11.4 15.5 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease RPW8 PF05659.11 CDJ63266.1 - 0.59 9.8 11.5 0.43 10.3 0.6 2.8 1 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 KxDL PF10241.9 CDJ63266.1 - 0.63 10.4 25.4 0.1 12.9 4.8 3.9 2 2 2 4 4 4 0 Uncharacterized conserved protein XLF PF09302.11 CDJ63266.1 - 0.66 10.1 16.4 0.47 10.6 11.1 2.5 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Poty_PP PF08440.10 CDJ63266.1 - 0.87 8.6 10.1 1.1 8.3 4.8 2.7 2 1 1 3 3 3 0 Potyviridae polyprotein Baculo_p24 PF05073.12 CDJ63266.1 - 1.4 8.7 14.3 4 7.2 0.8 2.6 1 1 1 2 2 2 0 Baculovirus P24 capsid protein FUSC PF04632.12 CDJ63266.1 - 1.9 6.9 15.1 9.8 4.6 15.1 1.9 1 1 0 1 1 1 0 Fusaric acid resistance protein family Med30 PF11315.8 CDJ63266.1 - 2.1 8.5 17.8 1.3 9.2 4.0 3.6 1 1 2 4 4 4 0 Mediator complex subunit 30 Mt_ATP-synt_D PF05873.12 CDJ63266.1 - 2.3 8.0 10.5 23 4.8 0.1 2.8 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Cytochrom_B562 PF07361.11 CDJ63266.1 - 3.3 8.4 11.5 5.9 7.6 3.0 2.9 1 1 1 2 2 2 0 Cytochrome b562 AAA_13 PF13166.6 CDJ63266.1 - 4.6 5.7 22.5 10 4.6 22.5 1.5 1 1 0 1 1 1 0 AAA domain DivIVA PF05103.13 CDJ63266.1 - 5 7.2 24.8 2.7 8.1 4.6 3.2 2 1 0 2 2 2 0 DivIVA protein DUF641 PF04859.12 CDJ63266.1 - 6.2 7.2 25.2 2 8.8 16.6 3.2 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Golgin_A5 PF09787.9 CDJ63266.1 - 7.6 5.9 32.3 0.4 10.1 18.7 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Snapin_Pallidin PF14712.6 CDJ63266.1 - 7.9 7.0 30.9 2 8.9 8.0 3.7 2 2 0 3 3 3 0 Snapin/Pallidin PH PF00169.29 CDJ63267.1 - 0.026 15.0 0.0 0.92 10.0 0.0 2.9 2 1 0 2 2 2 0 PH domain Spt20 PF12090.8 CDJ63269.1 - 0.099 12.2 21.8 0.11 12.2 21.8 1.0 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ63269.1 - 0.24 11.4 14.5 0.24 11.3 14.5 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3043 PF11241.8 CDJ63269.1 - 0.48 10.4 6.4 0.55 10.2 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF3123 PF11321.8 CDJ63269.1 - 0.78 10.4 5.0 1.3 9.7 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3123) SelP_N PF04592.14 CDJ63269.1 - 1.2 8.5 14.1 1.3 8.4 14.1 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Presenilin PF01080.17 CDJ63269.1 - 1.5 7.5 5.3 1.5 7.5 5.3 1.0 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ63269.1 - 2 7.3 18.8 2.1 7.2 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ63269.1 - 2.7 9.0 7.1 3 8.9 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4551 PF15087.6 CDJ63269.1 - 2.8 6.7 9.2 2.8 6.7 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3464 PF11947.8 CDJ63269.1 - 3 7.6 7.0 3 7.6 7.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 UPF0560 PF10577.9 CDJ63269.1 - 4.6 5.6 11.3 4.5 5.7 11.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TERB2 PF15101.6 CDJ63269.1 - 5.2 7.1 9.9 5.3 7.0 9.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TFIIA PF03153.13 CDJ63269.1 - 7.6 6.4 25.0 7.4 6.5 25.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_2 PF13923.6 CDJ63270.1 - 1.6e-09 37.4 10.2 1.6e-09 37.4 10.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) LON_substr_bdg PF02190.16 CDJ63270.1 - 6.7e-08 32.7 0.0 1.9e-07 31.2 0.0 1.7 2 1 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4 PF00097.25 CDJ63270.1 - 2e-07 30.8 10.3 2e-07 30.8 10.3 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ63270.1 - 4e-07 30.3 9.7 4e-07 30.3 9.7 2.8 3 0 0 3 3 2 1 Ring finger domain U-box PF04564.15 CDJ63270.1 - 2.3e-06 27.7 4.1 2.4e-06 27.6 0.2 2.3 2 0 0 2 2 2 1 U-box domain zf-RING_UBOX PF13445.6 CDJ63270.1 - 3.1e-06 27.1 10.7 3.1e-06 27.1 10.7 2.7 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ63270.1 - 8.6e-06 25.5 10.2 8.6e-06 25.5 10.2 2.5 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ63270.1 - 3.9e-05 23.7 12.3 3.9e-05 23.7 12.3 2.5 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ63270.1 - 7.3e-05 22.6 8.4 7.3e-05 22.6 8.4 3.0 2 1 1 3 3 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CDJ63270.1 - 0.0019 18.4 7.7 0.0019 18.4 7.7 3.3 4 1 0 4 4 3 1 RING-H2 zinc finger domain K_channel_TID PF07941.11 CDJ63270.1 - 0.0034 17.8 6.4 0.0034 17.8 6.4 8.8 7 3 2 9 9 4 2 Potassium channel Kv1.4 tandem inactivation domain RskA PF10099.9 CDJ63270.1 - 0.0077 16.5 6.8 0.0077 16.5 6.8 4.3 4 0 0 4 4 4 2 Anti-sigma-K factor rskA OmpH PF03938.14 CDJ63270.1 - 0.013 15.8 41.3 0.14 12.5 6.1 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Spt20 PF12090.8 CDJ63270.1 - 0.018 14.7 45.5 0.69 9.5 6.6 3.2 3 0 0 3 3 3 0 Spt20 family zf-RING_4 PF14570.6 CDJ63270.1 - 0.025 14.4 3.8 0.025 14.4 3.8 2.6 4 0 0 4 4 3 0 RING/Ubox like zinc-binding domain E7 PF00527.18 CDJ63270.1 - 0.55 10.5 14.6 0.041 14.1 3.3 3.2 3 0 0 3 3 3 0 E7 protein, Early protein DUF2722 PF10846.8 CDJ63270.1 - 0.65 8.9 35.5 0.33 9.9 10.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) DUF1053 PF06327.14 CDJ63270.1 - 6.4 7.4 8.3 7.3 7.2 0.6 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) zf-RING_10 PF16685.5 CDJ63270.1 - 8.5 6.6 18.0 0.051 13.7 8.6 2.1 2 0 0 2 2 1 0 zinc RING finger of MSL2 Ribosomal_60s PF00428.19 CDJ63271.1 - 0.046 14.3 4.7 0.076 13.6 4.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ63271.1 - 0.064 13.2 19.8 0.08 12.9 19.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NQRA PF05896.11 CDJ63271.1 - 0.09 12.2 3.5 0.13 11.7 2.8 1.6 1 1 1 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RNase_J_C PF17770.1 CDJ63271.1 - 0.21 12.7 1.0 0.4 11.7 1.0 1.4 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain DUF4407 PF14362.6 CDJ63271.1 - 0.3 10.4 7.0 0.35 10.2 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CsgF PF10614.9 CDJ63271.1 - 0.31 11.2 8.8 0.5 10.6 8.8 1.3 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein Spt20 PF12090.8 CDJ63271.1 - 0.42 10.2 15.9 0.6 9.7 15.9 1.4 1 0 0 1 1 1 0 Spt20 family Spore_III_AF PF09581.10 CDJ63271.1 - 2.4 8.1 7.0 4 7.4 7.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) EIF4E-T PF10477.9 CDJ63271.1 - 9.6 4.9 18.6 0.19 10.5 12.1 1.3 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E NAP PF00956.18 CDJ63272.1 - 8.4e-17 61.2 3.3 1.5e-11 44.0 0.0 3.1 2 1 1 3 3 3 3 Nucleosome assembly protein (NAP) SR-25 PF10500.9 CDJ63272.1 - 5.7e-05 22.8 3.3 7.6e-05 22.4 3.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Tmemb_cc2 PF10267.9 CDJ63272.1 - 0.012 14.8 3.6 0.015 14.5 3.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Sec3_C PF09763.9 CDJ63272.1 - 0.067 11.6 0.2 0.073 11.5 0.2 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF229 PF02995.17 CDJ63272.1 - 0.25 9.9 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) EELM2 PF15863.5 CDJ63273.1 - 0.00022 21.4 0.0 0.058 13.5 0.0 2.4 2 1 0 2 2 2 2 Extended EGL-27 and MTA1 homology domain SPX PF03105.19 CDJ63273.1 - 0.48 10.3 12.2 0.67 9.8 12.2 1.2 1 0 0 1 1 1 0 SPX domain RNA_pol_Rpb5_C PF01191.19 CDJ63274.1 - 3.5e-15 55.6 0.1 3.5e-15 55.6 0.1 3.9 2 1 1 3 3 3 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CDJ63274.1 - 0.0019 18.7 0.0 0.0019 18.7 0.0 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain DUF4746 PF15928.5 CDJ63274.1 - 0.022 14.2 10.7 0.051 13.0 10.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) Gram_pos_anchor PF00746.21 CDJ63275.1 - 0.23 11.4 0.9 11 6.0 0.2 3.0 2 1 0 2 2 2 0 LPXTG cell wall anchor motif DUF2339 PF10101.9 CDJ63275.1 - 1.1 7.7 6.5 1.6 7.2 6.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF4667 PF15700.5 CDJ63277.1 - 0.0002 21.5 5.0 0.0002 21.5 5.0 4.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4667) DUF3682 PF12446.8 CDJ63277.1 - 0.00052 20.5 20.4 0.00052 20.5 20.4 9.0 6 3 1 7 7 7 1 Protein of unknown function (DUF3682) MecA PF05389.12 CDJ63277.1 - 1.5 8.4 21.8 2.1 7.9 2.6 3.4 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) PEX11 PF05648.14 CDJ63277.1 - 6.7 6.1 20.5 0.2 11.1 1.7 3.6 3 0 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) PA14 PF07691.12 CDJ63278.1 - 1.3e-12 47.7 0.1 1.7e-11 44.2 0.1 2.2 1 1 0 1 1 1 1 PA14 domain LCCL PF03815.19 CDJ63278.1 - 3.7e-08 33.4 0.0 1.3e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 LCCL domain ABC_tran PF00005.27 CDJ63279.1 - 1.4e-35 122.8 4.3 5.4e-15 56.1 0.0 5.4 4 1 0 4 4 4 2 ABC transporter ABC_membrane PF00664.23 CDJ63279.1 - 4.6e-19 69.1 0.2 1.6e-08 34.5 0.0 3.3 2 1 1 3 3 3 3 ABC transporter transmembrane region SPX PF03105.19 CDJ63279.1 - 5e-06 26.7 20.1 0.0035 17.3 0.0 3.6 3 1 0 3 3 3 2 SPX domain Spt20 PF12090.8 CDJ63279.1 - 2.7e-05 23.9 41.6 0.013 15.1 2.0 3.5 3 0 0 3 3 3 3 Spt20 family MMR_HSR1 PF01926.23 CDJ63279.1 - 5.7e-05 23.2 0.4 0.14 12.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 CDJ63279.1 - 7.7e-05 22.2 0.1 0.052 13.0 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ63279.1 - 0.00012 21.7 0.9 0.63 9.8 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 CDJ63279.1 - 0.007 15.5 2.8 7.4 5.5 0.1 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_21 PF13304.6 CDJ63279.1 - 0.022 14.6 7.5 1.8 8.3 0.8 3.7 2 2 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF1645 PF07816.11 CDJ63279.1 - 0.026 15.1 0.9 0.026 15.1 0.9 5.5 4 1 1 5 5 4 0 Protein of unknown function (DUF1645) FtsK_SpoIIIE PF01580.18 CDJ63279.1 - 0.029 13.7 0.3 2 7.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 CDJ63279.1 - 0.032 14.1 8.1 1.2 9.0 0.8 3.1 3 0 0 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 CDJ63279.1 - 0.039 13.5 0.4 4.5 6.8 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 CDJ63279.1 - 0.04 13.5 0.8 5.3 6.6 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.15 CDJ63279.1 - 0.13 11.0 0.4 0.95 8.2 0.1 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein Pox_A32 PF04665.12 CDJ63279.1 - 0.21 11.0 1.4 6.9 6.0 0.2 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein Tubulin_3 PF14881.6 CDJ63279.1 - 0.31 10.7 6.7 1.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Tubulin domain DUF87 PF01935.17 CDJ63279.1 - 0.41 10.7 9.2 2.5 8.2 0.0 3.6 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_22 PF13401.6 CDJ63279.1 - 0.47 10.7 10.0 1.4 9.2 0.0 3.9 4 0 0 4 4 4 0 AAA domain Roc PF08477.13 CDJ63279.1 - 0.5 10.6 7.4 3.6 7.8 0.0 3.2 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ALMT PF11744.8 CDJ63280.1 - 0.33 9.8 25.4 0.35 9.7 25.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Raftlin PF15250.6 CDJ63280.1 - 8.8 5.0 32.2 9.3 4.9 32.2 1.0 1 0 0 1 1 1 0 Raftlin CCSAP PF15748.5 CDJ63281.1 - 3.3 7.8 17.2 0.61 10.2 13.2 1.7 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated AhpC-TSA PF00578.21 CDJ63282.1 - 8.8e-33 112.9 0.0 1.2e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CDJ63282.1 - 6.6e-14 51.5 0.3 1.1e-13 50.8 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CDJ63282.1 - 9e-14 51.4 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin FAM199X PF15814.5 CDJ63283.1 - 3.7 6.5 17.5 4.1 6.4 17.5 1.1 1 0 0 1 1 1 0 Protein family FAM199X Zip PF02535.22 CDJ63283.1 - 7.6 5.6 7.2 8.8 5.4 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Band_3_cyto PF07565.13 CDJ63283.1 - 8.5 6.1 11.0 9.6 5.9 11.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ribosomal_60s PF00428.19 CDJ63284.1 - 2.6 8.7 38.4 1.2 9.8 4.6 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Ribosomal_60s PF00428.19 CDJ63285.1 - 0.45 11.1 32.5 3.2 8.4 13.9 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein PAP2 PF01569.21 CDJ63286.1 - 0.041 13.6 17.7 0.024 14.4 8.8 3.3 2 1 0 2 2 2 0 PAP2 superfamily SR-25 PF10500.9 CDJ63286.1 - 1.8 8.1 19.2 2.7 7.5 19.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rrn6 PF10214.9 CDJ63287.1 - 0.041 12.4 4.1 0.043 12.3 4.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Inj_translocase PF16928.5 CDJ63287.1 - 0.067 12.6 9.0 0.088 12.2 9.0 1.2 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Presenilin PF01080.17 CDJ63287.1 - 0.13 11.0 0.8 0.14 10.9 0.8 1.1 1 0 0 1 1 1 0 Presenilin Ctr PF04145.15 CDJ63287.1 - 0.15 12.7 0.1 0.17 12.5 0.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Spt20 PF12090.8 CDJ63287.1 - 0.74 9.4 11.6 0.93 9.1 11.6 1.1 1 0 0 1 1 1 0 Spt20 family DUF2514 PF10721.9 CDJ63287.1 - 1.3 9.0 10.8 2 8.5 10.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) RSRP PF17069.5 CDJ63288.1 - 1.7e-05 24.6 40.9 1.7e-05 24.6 40.9 5.4 5 0 0 5 5 5 1 Arginine/Serine-Rich protein 1 SPX PF03105.19 CDJ63288.1 - 0.00016 21.7 9.6 0.00016 21.7 9.6 5.0 1 1 1 3 3 3 1 SPX domain Spt20 PF12090.8 CDJ63288.1 - 0.0017 18.0 58.5 0.037 13.6 9.6 4.4 4 0 0 4 4 4 3 Spt20 family SUIM_assoc PF16619.5 CDJ63288.1 - 0.0026 17.8 2.3 0.0026 17.8 2.3 7.5 6 1 0 6 6 6 3 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 CDJ63288.1 - 0.066 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MecA PF05389.12 CDJ63288.1 - 1.2 8.7 5.6 7.3 6.1 0.0 3.2 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) ASH PF15780.5 CDJ63289.1 - 8e-05 22.8 0.2 6.9 6.9 0.0 4.8 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CDC45 PF02724.14 CDJ63289.1 - 0.0014 17.0 2.5 0.0014 17.0 2.5 4.7 5 1 0 5 5 5 1 CDC45-like protein TFIIA PF03153.13 CDJ63289.1 - 0.0019 18.3 162.9 0.29 11.1 22.5 8.5 8 0 0 8 8 8 8 Transcription factor IIA, alpha/beta subunit BPL_N PF09825.9 CDJ63292.1 - 1.2 8.1 20.8 1.5 7.8 20.8 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal LAP1C PF05609.12 CDJ63292.1 - 7.5 5.5 42.4 9.9 5.1 42.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hamartin PF04388.12 CDJ63292.1 - 9.7 4.7 41.9 11 4.5 41.9 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4834 PF16118.5 CDJ63293.1 - 0.0053 17.7 2.5 0.0071 17.3 1.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) AIM3 PF17096.5 CDJ63293.1 - 0.05 14.5 1.8 0.11 13.4 1.8 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DUF4770 PF15994.5 CDJ63293.1 - 0.079 13.2 4.6 0.13 12.5 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) EMC3_TMCO1 PF01956.16 CDJ63293.1 - 0.09 12.5 0.3 0.17 11.6 0.3 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like VKG_Carbox PF05090.14 CDJ63293.1 - 0.16 10.7 0.5 0.25 10.1 0.5 1.2 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Presenilin PF01080.17 CDJ63293.1 - 0.22 10.2 3.1 0.28 9.9 3.1 1.3 1 0 0 1 1 1 0 Presenilin G0-G1_switch_2 PF15103.6 CDJ63293.1 - 8.8 6.8 8.6 1.1 9.8 2.2 2.4 3 0 0 3 3 3 0 G0/G1 switch protein 2 DUF3800 PF12686.7 CDJ63294.1 - 1.4 9.6 5.9 2.5e+02 2.3 5.9 4.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Spt5-NGN PF03439.13 CDJ63295.1 - 6e-15 54.9 0.0 1.4e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt20 PF12090.8 CDJ63295.1 - 0.0093 15.6 5.0 0.0093 15.6 5.0 2.2 2 0 0 2 2 2 1 Spt20 family Spt5_N PF11942.8 CDJ63295.1 - 0.014 16.3 20.4 0.014 16.3 20.4 3.2 2 1 1 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Ndc1_Nup PF09531.10 CDJ63295.1 - 0.35 9.5 14.3 0.36 9.5 14.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NAM-associated PF14303.6 CDJ63295.1 - 1.5 9.5 30.4 2.6 8.8 30.4 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF2722 PF10846.8 CDJ63295.1 - 2.5 6.9 35.3 0.042 12.8 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4551 PF15087.6 CDJ63295.1 - 2.7 6.7 18.0 3 6.6 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4834 PF16118.5 CDJ63295.1 - 5 8.2 25.2 5.4 8.1 2.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SOBP PF15279.6 CDJ63295.1 - 5.1 7.6 17.4 6.7 7.2 17.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Draxin PF15550.6 CDJ63295.1 - 5.3 6.8 18.8 7.6 6.3 18.8 1.3 1 0 0 1 1 1 0 Draxin SR-25 PF10500.9 CDJ63295.1 - 5.6 6.5 42.5 0.082 12.5 30.5 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Nop14 PF04147.12 CDJ63296.1 - 4.2e-12 45.2 55.8 4.2e-12 45.2 55.8 5.5 3 1 1 4 4 4 2 Nop14-like family AAA_23 PF13476.6 CDJ63296.1 - 0.0061 17.1 8.4 0.0061 17.1 8.4 5.5 5 1 0 5 5 5 2 AAA domain TctB PF07331.11 CDJ63296.1 - 1.6 9.0 8.6 1.1e+02 3.1 2.7 4.6 3 1 1 4 4 4 0 Tripartite tricarboxylate transporter TctB family Dus PF01207.17 CDJ63297.1 - 9.3e-10 38.1 8.5 1.2e-07 31.2 8.5 2.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) RNase_Zc3h12a PF11977.8 CDJ63297.1 - 0.072 12.9 0.3 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain Ribosomal_60s PF00428.19 CDJ63297.1 - 3.2 8.4 15.3 0.62 10.7 5.7 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein FAM101 PF15068.6 CDJ63298.1 - 1.3 8.9 7.9 2.7 7.9 7.9 1.6 1 1 0 1 1 1 0 FAM101 family RskA PF10099.9 CDJ63298.1 - 2 8.6 19.3 2.7 8.2 19.3 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Itfg2 PF15907.5 CDJ63298.1 - 2.6 7.0 9.4 3 6.8 9.4 1.0 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 IHABP4_N PF16174.5 CDJ63298.1 - 2.7 8.6 23.9 3.2 8.3 23.9 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal TFIIA PF03153.13 CDJ63298.1 - 9.3 6.1 38.8 9.7 6.1 38.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sugar_tr PF00083.24 CDJ63299.1 - 6.5e-49 167.0 16.0 1.8e-33 116.1 2.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDJ63299.1 - 1.2e-19 70.5 50.1 3.6e-11 42.6 21.5 4.4 4 1 0 4 4 4 3 Major Facilitator Superfamily CLN3 PF02487.17 CDJ63299.1 - 1.6e-07 30.7 3.0 0.0023 17.1 0.6 2.8 2 0 0 2 2 2 2 CLN3 protein DUF4834 PF16118.5 CDJ63299.1 - 0.0043 18.0 0.2 0.0043 18.0 0.2 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4834) Band_3_cyto PF07565.13 CDJ63299.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.9 3 0 0 3 3 3 0 Band 3 cytoplasmic domain SID-1_RNA_chan PF13965.6 CDJ63299.1 - 0.021 13.3 1.0 2 6.7 0.0 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 RskA PF10099.9 CDJ63299.1 - 0.049 13.9 0.2 0.049 13.9 0.2 6.6 2 2 2 4 4 3 0 Anti-sigma-K factor rskA IBV_3C PF03620.13 CDJ63299.1 - 0.055 14.0 2.9 8.5 6.9 0.2 3.0 2 0 0 2 2 2 0 IBV 3C protein FHIPEP PF00771.20 CDJ63299.1 - 0.39 9.1 14.8 0.023 13.2 1.4 2.6 2 0 0 2 2 2 0 FHIPEP family Exonuc_VII_L PF02601.15 CDJ63299.1 - 0.5 9.9 22.3 0.092 12.3 2.9 2.9 3 0 0 3 3 3 0 Exonuclease VII, large subunit DUF1980 PF09323.10 CDJ63299.1 - 1.2 9.0 11.5 0.3 11.0 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) PUB PF09409.10 CDJ63300.1 - 9.2e-06 25.5 0.0 2.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 PUB domain FAM60A PF15396.6 CDJ63300.1 - 0.1 12.6 18.2 0.24 11.4 9.1 3.1 3 0 0 3 3 3 0 Protein Family FAM60A PRCC PF10253.9 CDJ63300.1 - 0.14 12.9 42.0 0.11 13.2 13.6 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Spore_coat_CotO PF14153.6 CDJ63300.1 - 0.29 11.0 39.8 0.024 14.6 15.0 3.4 3 0 0 3 3 3 0 Spore coat protein CotO DUF2052 PF09747.9 CDJ63300.1 - 0.39 10.8 28.3 0.17 12.0 11.6 3.2 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Cwf_Cwc_15 PF04889.12 CDJ63300.1 - 1.1 9.0 26.5 1.1 8.9 0.1 3.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_Rpc4 PF05132.14 CDJ63300.1 - 1.2 9.6 24.7 0.14 12.6 6.8 3.4 3 0 0 3 3 3 0 RNA polymerase III RPC4 Shadoo PF14999.6 CDJ63300.1 - 1.2 9.2 16.2 2.1 8.5 12.1 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Pex14_N PF04695.13 CDJ63300.1 - 2.6 8.7 59.8 1 10.0 10.0 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 CDJ63300.1 - 3.1 7.5 29.1 0.27 11.0 12.7 3.1 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 CDJ63300.1 - 3.2 8.0 22.7 5.1 7.3 10.3 3.2 3 0 0 3 3 3 0 GAGA binding protein-like family TCP PF03634.13 CDJ63300.1 - 5 7.7 28.4 4.2 7.9 14.2 3.3 3 0 0 3 3 3 0 TCP family transcription factor DUF913 PF06025.12 CDJ63300.1 - 7.2 5.5 16.7 1.2 8.0 7.2 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 CDJ63300.1 - 9.7 6.3 27.0 14 5.8 1.9 3.4 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Utp14 PF04615.13 CDJ63301.1 - 0.61 8.6 25.5 0.84 8.1 25.5 1.2 1 0 0 1 1 1 0 Utp14 protein RRM_1 PF00076.22 CDJ63302.1 - 4.6e-15 55.2 0.1 9.4e-15 54.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 CDJ63302.1 - 0.00091 18.9 13.2 0.00091 18.9 13.2 3.8 3 1 0 3 3 3 1 Spt20 family SUIM_assoc PF16619.5 CDJ63302.1 - 0.0021 18.1 7.5 0.0021 18.1 7.5 5.6 5 1 0 5 5 5 3 Unstructured region C-term to UIM in Ataxin3 AF-4 PF05110.13 CDJ63302.1 - 0.003 15.8 19.2 0.003 15.8 19.2 2.2 2 0 0 2 2 2 1 AF-4 proto-oncoprotein Suf PF05843.14 CDJ63302.1 - 0.0054 16.8 7.4 0.0054 16.8 7.4 2.7 1 1 1 2 2 2 1 Suppressor of forked protein (Suf) RRM_7 PF16367.5 CDJ63302.1 - 0.012 15.7 0.0 0.012 15.7 0.0 2.5 3 1 0 3 3 3 0 RNA recognition motif ALMT PF11744.8 CDJ63302.1 - 1.3 7.8 16.7 1.3 7.8 8.8 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ63302.1 - 1.6 7.7 18.4 0.71 8.8 6.4 2.1 2 0 0 2 2 2 0 Solute carrier family 12 DUF4667 PF15700.5 CDJ63302.1 - 4.3 7.4 27.4 0.2 11.8 14.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) FCP1_C PF09309.10 CDJ63302.1 - 4.5 7.1 29.0 0.18 11.7 11.4 3.3 3 0 0 3 3 3 0 FCP1, C-terminal RRM_1 PF00076.22 CDJ63303.1 - 8.4e-18 64.0 0.1 1.3e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ63303.1 - 8.5e-05 22.6 0.0 0.00018 21.5 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ63303.1 - 0.0062 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CDJ63303.1 - 0.043 13.9 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Nop16 PF09420.10 CDJ63304.1 - 1.5e-10 41.5 0.1 1.5e-10 41.5 0.1 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein Nop16 DUF755 PF05501.11 CDJ63304.1 - 0.011 16.0 7.3 0.011 16.0 7.3 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF755) Myb_DNA-bind_4 PF13837.6 CDJ63304.1 - 0.029 14.8 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Macro PF01661.21 CDJ63305.1 - 0.00022 21.2 0.0 0.0014 18.7 0.0 2.3 2 0 0 2 2 2 1 Macro domain SUIM_assoc PF16619.5 CDJ63305.1 - 0.0017 18.4 0.0 0.0017 18.4 0.0 5.3 5 2 0 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 DUF4050 PF13259.6 CDJ63305.1 - 0.037 14.3 1.6 0.061 13.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Spt20 PF12090.8 CDJ63305.1 - 0.54 9.8 42.5 0.085 12.5 9.6 3.3 3 0 0 3 3 3 0 Spt20 family Chromo PF00385.24 CDJ63306.1 - 3.5e-14 52.4 0.0 7.4e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CDJ63306.1 - 1.9e-11 44.2 0.0 3.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain SR-25 PF10500.9 CDJ63308.1 - 7.6 6.1 16.5 0.14 11.8 6.3 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ63309.1 - 0.0016 18.5 1.1 0.0018 18.3 1.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ63309.1 - 0.0021 17.7 5.5 0.0021 17.7 5.5 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Pkinase_Tyr PF07714.17 CDJ63309.1 - 0.0026 17.1 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDJ63309.1 - 0.095 12.1 0.0 5 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain Med3 PF11593.8 CDJ63309.1 - 0.11 11.7 6.9 0.19 10.9 6.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3446 PF11928.8 CDJ63309.1 - 1.3 9.3 14.6 0.067 13.5 8.1 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain FTZ PF03867.14 CDJ63309.1 - 3.9 6.9 5.8 0.74 9.3 1.4 1.8 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region ANAPC1 PF12859.7 CDJ63309.1 - 9.2 6.8 10.3 7.2 7.2 7.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 1 DUF2722 PF10846.8 CDJ63310.1 - 0.00073 18.6 2.6 0.00073 18.6 2.6 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF2722) LRR_6 PF13516.6 CDJ63310.1 - 0.00089 19.1 7.5 19 5.6 0.2 6.5 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 CDJ63310.1 - 0.015 15.7 5.2 0.37 11.3 0.0 4.3 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) Cyt_bd_oxida_II PF02322.15 CDJ63311.1 - 0.09 12.1 18.8 0.11 11.9 18.8 1.0 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Spt20 PF12090.8 CDJ63311.1 - 0.8 9.3 14.7 1.1 8.9 14.7 1.1 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ63312.1 - 0.00055 20.3 6.7 0.00055 20.3 6.7 7.9 5 1 1 6 6 6 4 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ63312.1 - 0.0071 16.0 7.4 0.0071 16.0 7.4 6.2 4 1 2 6 6 6 3 Spt20 family SID-1_RNA_chan PF13965.6 CDJ63312.1 - 1.9 6.8 5.9 0.78 8.1 2.1 2.2 3 0 0 3 3 3 0 dsRNA-gated channel SID-1 Apt1 PF10351.9 CDJ63313.1 - 3.1 6.6 19.8 3.8 6.3 19.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tmemb_cc2 PF10267.9 CDJ63313.1 - 3.4 6.7 7.9 4 6.5 7.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SPX PF03105.19 CDJ63313.1 - 5.7 6.7 19.3 6.8 6.5 19.3 1.1 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 CDJ63314.1 - 0.00096 18.8 35.6 0.032 13.8 29.1 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ63314.1 - 0.0033 17.7 0.0 0.0033 17.7 0.0 5.4 2 1 2 5 5 5 1 Anti-sigma-K factor rskA Dicty_REP PF05086.12 CDJ63314.1 - 0.12 10.4 1.1 0.16 9.9 1.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SPX PF03105.19 CDJ63314.1 - 0.23 11.4 18.2 0.16 11.8 9.9 2.4 2 1 0 2 2 2 0 SPX domain Lin-8 PF03353.15 CDJ63314.1 - 2.3 7.7 19.4 2 7.9 11.7 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Sporozoite_P67 PF05642.11 CDJ63314.1 - 3.6 5.6 9.3 6.3 4.8 9.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1387 PF07139.11 CDJ63314.1 - 5.1 6.7 22.9 2.3 7.8 13.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Miga PF10265.9 CDJ63314.1 - 6.1 5.7 23.3 0.0066 15.5 10.9 2.3 2 1 0 2 2 2 0 Mitoguardin DUF4603 PF15376.6 CDJ63314.1 - 6.5 4.0 17.7 12 3.1 17.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) XRN_M PF17846.1 CDJ63315.1 - 0.17 10.8 1.9 0.21 10.5 1.9 1.1 1 0 0 1 1 1 0 Xrn1 helical domain CCDC-167 PF15188.6 CDJ63315.1 - 0.67 10.3 6.2 1.5 9.2 6.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 V_ATPase_I PF01496.19 CDJ63315.1 - 1.2 7.0 6.1 1.3 6.9 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 CDJ63316.1 - 0.0061 16.0 0.0 0.0076 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63316.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase TPR_1 PF00515.28 CDJ63317.1 - 1.7e-51 170.0 26.8 7e-09 35.1 0.0 7.4 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ63317.1 - 8e-41 134.9 25.8 3.8e-06 26.6 0.0 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ63317.1 - 4.1e-26 90.4 11.2 9.1e-09 34.9 1.9 6.3 5 1 1 6 6 6 5 TPR repeat TPR_8 PF13181.6 CDJ63317.1 - 4.6e-23 79.5 21.4 0.00091 19.3 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ63317.1 - 3.2e-21 75.4 6.6 2.7e-11 43.6 0.4 5.8 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ63317.1 - 5e-17 61.1 12.1 0.066 14.1 0.0 9.4 6 3 4 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ63317.1 - 2.9e-15 56.6 21.1 0.00061 20.4 0.3 7.1 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ63317.1 - 1.3e-13 50.0 8.0 0.0011 18.8 0.1 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat STI1 PF17830.1 CDJ63317.1 - 2.7e-13 49.6 6.4 3e-07 30.3 2.8 3.4 2 0 0 2 2 2 2 STI1 domain TPR_10 PF13374.6 CDJ63317.1 - 2.3e-11 43.2 9.3 0.072 13.0 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ63317.1 - 7.2e-11 41.7 16.1 0.028 14.8 0.3 7.4 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ63317.1 - 1.1e-10 41.5 5.4 0.0048 17.0 0.0 6.6 3 1 2 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ63317.1 - 7e-07 29.7 29.0 0.0012 19.3 1.6 7.3 6 2 1 8 8 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ63317.1 - 8.8e-07 28.9 8.2 0.27 11.3 0.0 6.0 4 1 1 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 CDJ63317.1 - 0.00033 21.1 10.1 3.2 8.6 0.3 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ63317.1 - 0.054 13.7 15.0 9.1 6.6 0.0 4.8 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 CDJ63317.1 - 0.074 13.3 5.6 0.53 10.7 0.1 4.1 4 0 0 4 4 3 0 PPR repeat TPR_21 PF09976.9 CDJ63317.1 - 0.097 12.4 19.8 0.23 11.1 2.7 4.5 2 1 2 4 4 4 0 Tetratricopeptide repeat-like domain MIT PF04212.18 CDJ63317.1 - 0.11 12.5 14.2 25 5.0 0.2 5.1 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain PPR_2 PF13041.6 CDJ63317.1 - 0.32 11.2 1.6 14 5.9 0.1 2.8 2 0 0 2 2 2 0 PPR repeat family RPN7 PF10602.9 CDJ63317.1 - 0.58 9.8 12.7 4 7.1 6.6 3.8 1 1 2 3 3 3 0 26S proteasome subunit RPN7 TPR_3 PF07720.12 CDJ63317.1 - 7.8 6.6 10.6 3.5 7.7 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S17 PF00366.20 CDJ63318.1 - 5.8e-13 48.7 0.0 9.9e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 His_Phos_1 PF00300.22 CDJ63320.1 - 6.8e-45 153.2 0.0 9.3e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 CDJ63320.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Ribosomal_S17e PF00833.18 CDJ63321.1 - 6.8e-60 200.4 1.8 7.7e-60 200.2 1.8 1.0 1 0 0 1 1 1 1 Ribosomal S17 SpoIIE PF07228.12 CDJ63322.1 - 0.00035 20.5 10.4 0.02 14.8 0.1 3.5 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) CDC45 PF02724.14 CDJ63322.1 - 0.0013 17.1 7.6 0.0013 17.1 7.6 2.6 3 0 0 3 3 3 1 CDC45-like protein Zip PF02535.22 CDJ63322.1 - 3.5 6.8 28.0 0.11 11.7 4.3 3.2 3 0 0 3 3 3 0 ZIP Zinc transporter DUF913 PF06025.12 CDJ63322.1 - 4.6 6.1 29.1 0.0053 15.8 4.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) RskA PF10099.9 CDJ63322.1 - 6.2 7.1 0.0 6.2 7.1 0.0 12.7 3 3 5 10 10 10 0 Anti-sigma-K factor rskA Hydrolase_4 PF12146.8 CDJ63323.1 - 2.5e-11 43.3 0.0 1.3e-05 24.6 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ63323.1 - 1.2e-09 39.2 24.5 1.3e-08 35.8 24.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Collagen PF01391.18 CDJ63323.1 - 5e-07 29.4 31.8 2.2e-05 24.1 19.1 2.6 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) Abhydrolase_1 PF00561.20 CDJ63323.1 - 9.8e-07 28.7 0.4 0.00019 21.2 0.2 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Thioesterase PF00975.20 CDJ63323.1 - 0.013 15.6 0.1 0.024 14.8 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain PHD PF00628.29 CDJ63324.1 - 0.0013 18.6 3.2 0.0013 18.6 3.2 3.5 3 0 0 3 3 3 1 PHD-finger SPX PF03105.19 CDJ63324.1 - 0.14 12.1 0.0 0.14 12.1 0.0 6.7 2 1 2 5 5 5 0 SPX domain zf-MIZ PF02891.20 CDJ63325.1 - 7.4e-10 38.4 2.1 1.8e-06 27.6 0.1 3.0 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger Ank_2 PF12796.7 CDJ63326.1 - 1.9e-23 82.8 0.1 2.9e-09 37.4 0.1 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ63326.1 - 1.5e-20 73.3 1.9 7.5e-10 39.2 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ63326.1 - 2.4e-20 70.5 0.3 5.7e-05 23.2 0.1 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CDJ63326.1 - 1.2e-18 66.9 2.8 1.2e-06 28.7 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CDJ63326.1 - 2.9e-18 65.4 0.9 0.00023 21.5 0.2 4.7 4 0 0 4 4 4 4 Ankyrin repeat Pex14_N PF04695.13 CDJ63326.1 - 0.39 11.4 11.1 0.06 14.0 6.9 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AF-4 PF05110.13 CDJ63326.1 - 1.9 6.5 23.8 2.4 6.1 23.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GREB1 PF15782.5 CDJ63326.1 - 2.3 5.2 12.5 3 4.8 12.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 CDJ63326.1 - 4.5 5.8 9.3 6.7 5.3 9.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TP6A_N PF04406.14 CDJ63327.1 - 1.3e-10 41.1 0.6 2.4e-10 40.3 0.1 1.7 2 0 0 2 2 2 1 Type IIB DNA topoisomerase Sdh5 PF03937.16 CDJ63328.1 - 9.6e-12 44.7 0.1 3.5e-10 39.7 0.1 2.4 1 1 0 1 1 1 1 Flavinator of succinate dehydrogenase DUF4347 PF14252.6 CDJ63328.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4347) Aldo_ket_red PF00248.21 CDJ63329.1 - 1.5e-30 106.4 0.0 5.5e-26 91.5 0.0 2.0 1 1 0 2 2 2 2 Aldo/keto reductase family LCM PF04072.14 CDJ63330.1 - 6e-26 91.5 0.1 2.9e-24 86.1 0.0 2.4 2 1 0 2 2 2 2 Leucine carboxyl methyltransferase OAR PF03826.17 CDJ63331.1 - 0.083 12.7 1.8 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 OAR domain AP2 PF00847.20 CDJ63332.1 - 2.8e-10 40.3 1.2 2.8e-10 40.3 1.2 1.9 2 0 0 2 2 2 1 AP2 domain NifU_N PF01592.16 CDJ63333.1 - 4.9e-48 162.5 0.1 6e-48 162.2 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Sec1 PF00995.23 CDJ63334.1 - 1.7e-69 235.6 0.0 9.8e-69 233.1 0.0 1.9 1 1 0 1 1 1 1 Sec1 family UPF0121 PF03661.13 CDJ63335.1 - 3e-12 46.5 0.5 5.3e-12 45.7 0.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Glyco_hydro_79n PF03662.14 CDJ63335.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain Ephrin_rec_like PF07699.13 CDJ63336.1 - 2.6e-28 97.5 117.2 1.4e-08 34.4 2.9 11.6 11 1 0 11 11 11 7 Putative ephrin-receptor like PAN_4 PF14295.6 CDJ63336.1 - 0.00086 19.2 0.8 0.0058 16.5 0.8 2.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 CDJ63336.1 - 0.017 15.2 1.8 0.14 12.3 1.8 2.7 1 0 0 1 1 1 0 PAN-like domain Uso1_p115_C PF04871.13 CDJ63336.1 - 0.028 14.8 4.0 0.058 13.8 4.0 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HALZ PF02183.18 CDJ63336.1 - 0.098 12.9 1.1 0.19 12.0 1.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper He_PIG PF05345.12 CDJ63336.1 - 1 9.6 3.1 1 9.6 0.3 2.5 2 0 0 2 2 2 0 Putative Ig domain EGF_MSP1_1 PF12946.7 CDJ63336.1 - 9.5 6.4 19.6 8.4 6.5 0.3 6.7 6 0 0 6 6 6 0 MSP1 EGF domain 1 RabGAP-TBC PF00566.18 CDJ63337.1 - 1.5e-33 116.3 0.1 1.5e-33 116.3 0.1 3.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 CDJ63337.1 - 0.015 15.8 0.0 0.057 13.9 0.0 2.0 1 0 0 1 1 1 0 Rhodanese-like domain RRM_1 PF00076.22 CDJ63338.1 - 9e-17 60.7 0.3 2.5e-16 59.2 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 CDJ63338.1 - 2.5e-13 50.5 0.2 4.4e-13 49.7 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G PHM7_cyt PF14703.6 CDJ63338.1 - 0.015 15.6 0.6 21 5.3 0.1 3.3 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter DA1-like PF12315.8 CDJ63340.1 - 1.1e-11 44.5 0.5 2.1e-11 43.6 0.5 1.4 1 0 0 1 1 1 1 Protein DA1 LIM PF00412.22 CDJ63340.1 - 0.39 11.0 0.1 0.068 13.4 10.6 5.1 4 1 1 5 5 5 0 LIM domain Vps39_2 PF10367.9 CDJ63340.1 - 0.95 9.9 4.8 0.39 11.2 0.4 2.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 EF-hand_6 PF13405.6 CDJ63341.1 - 5.2e-05 22.9 0.1 7e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CDJ63341.1 - 0.00026 21.4 0.1 0.0003 21.2 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ63341.1 - 0.00037 19.9 0.2 0.00054 19.3 0.2 1.3 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CDJ63341.1 - 0.00075 18.9 0.3 0.0011 18.3 0.3 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CDJ63341.1 - 0.005 16.6 0.1 0.0069 16.2 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair Ribosomal_S17_N PF16205.5 CDJ63342.1 - 2.1e-28 98.5 0.2 4.1e-28 97.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CDJ63342.1 - 3e-23 81.7 1.5 4.5e-23 81.1 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 EELM2 PF15863.5 CDJ63343.1 - 3.8e-78 261.5 0.1 5.7e-78 260.9 0.1 1.3 1 0 0 1 1 1 1 Extended EGL-27 and MTA1 homology domain PHD PF00628.29 CDJ63343.1 - 5.7e-09 35.7 6.8 5.7e-09 35.7 6.8 1.9 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 CDJ63343.1 - 0.02 14.5 7.8 0.052 13.2 2.7 3.1 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RanBP PF00641.18 CDJ63343.1 - 0.035 13.4 0.5 0.46 9.8 0.1 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others WD40_4 PF16300.5 CDJ63344.1 - 2.1e-19 69.1 0.0 4.2e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CDJ63344.1 - 9.8e-15 54.7 6.0 1.1e-06 29.2 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ63344.1 - 7.2e-10 39.0 0.0 0.00095 19.4 0.1 4.2 4 1 1 5 5 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 CDJ63344.1 - 4.5e-07 29.7 0.0 9.5e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Shugoshin_N PF07558.11 CDJ63344.1 - 0.0012 18.6 4.5 0.21 11.5 0.1 3.1 3 0 0 3 3 3 2 Shugoshin N-terminal coiled-coil region Nup160 PF11715.8 CDJ63344.1 - 0.0073 15.0 0.0 0.026 13.2 0.1 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.11 CDJ63344.1 - 0.01 15.8 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDJ63344.1 - 0.019 13.9 0.3 1.4 7.8 0.0 3.1 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CCDC144C PF14915.6 CDJ63344.1 - 0.025 13.7 25.7 0.038 13.1 25.7 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Exonuc_VII_L PF02601.15 CDJ63344.1 - 0.028 14.0 9.0 0.049 13.2 9.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 CDJ63344.1 - 0.036 14.4 21.3 0.28 11.5 7.2 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 CDJ63344.1 - 0.04 14.2 28.7 0.039 14.2 11.3 3.7 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF4795 PF16043.5 CDJ63344.1 - 0.24 11.0 16.7 0.4 10.3 16.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Nop16 PF09420.10 CDJ63344.1 - 0.3 11.1 14.6 0.57 10.2 14.6 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 DUF3015 PF11220.8 CDJ63344.1 - 0.3 10.9 1.6 0.52 10.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3015) Lebercilin PF15619.6 CDJ63344.1 - 0.34 10.5 33.5 1.8 8.2 13.0 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Atg14 PF10186.9 CDJ63344.1 - 0.39 9.8 20.8 0.6 9.2 20.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 CDJ63344.1 - 0.5 7.8 23.1 0.63 7.5 23.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 CDJ63344.1 - 0.76 10.2 29.1 0.055 13.9 8.5 2.2 1 1 1 2 2 2 0 Fez1 Spectrin PF00435.21 CDJ63344.1 - 0.93 10.0 23.1 0.26 11.8 10.1 2.6 1 1 1 2 2 2 0 Spectrin repeat GAS PF13851.6 CDJ63344.1 - 1.5 8.2 31.1 5.5 6.3 30.5 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding LMBR1 PF04791.16 CDJ63344.1 - 1.9 7.3 10.5 2.8 6.8 10.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TSC22 PF01166.18 CDJ63344.1 - 2.3 8.6 8.4 2.7 8.4 0.4 3.1 1 1 2 3 3 2 0 TSC-22/dip/bun family AAA_13 PF13166.6 CDJ63344.1 - 2.5 6.6 18.7 3.8 6.0 18.7 1.2 1 0 0 1 1 1 0 AAA domain TolA_bind_tri PF16331.5 CDJ63344.1 - 2.8 8.1 22.3 4.4 7.5 9.8 3.1 2 1 1 3 3 3 0 TolA binding protein trimerisation Spc29 PF17082.5 CDJ63344.1 - 3.3 7.5 13.3 2.4 7.9 6.5 2.6 1 1 2 3 3 3 0 Spindle Pole Component 29 HOOK PF05622.12 CDJ63344.1 - 3.5 5.7 29.3 4.9 5.2 10.9 2.0 1 1 1 2 2 2 0 HOOK protein ATG16 PF08614.11 CDJ63344.1 - 3.7 7.7 33.5 34 4.6 22.3 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Leu_zip PF15294.6 CDJ63344.1 - 4.6 6.7 26.2 14 5.1 19.8 2.0 1 1 1 2 2 2 0 Leucine zipper Noelin-1 PF12308.8 CDJ63344.1 - 6 6.9 9.5 1.4 8.9 1.8 2.5 1 1 2 3 3 3 0 Neurogenesis glycoprotein Tropomyosin_1 PF12718.7 CDJ63344.1 - 6.3 6.9 32.7 21 5.2 32.2 1.9 1 1 1 2 2 2 0 Tropomyosin like BRI3BP PF14965.6 CDJ63344.1 - 9.8 5.6 7.1 15 5.0 0.5 3.1 1 1 2 3 3 3 0 Negative regulator of p53/TP53 CAF1C_H4-bd PF12265.8 CDJ63346.1 - 2.3e-18 66.2 0.5 6.3e-18 64.8 0.5 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CDJ63346.1 - 5.7e-12 46.0 10.0 0.082 13.8 0.5 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ63346.1 - 0.00047 20.4 0.1 0.7 10.2 0.0 3.8 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ciart PF15673.5 CDJ63346.1 - 0.046 13.1 0.1 0.072 12.5 0.1 1.3 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor V-ATPase_G PF03179.15 CDJ63348.1 - 8.4e-25 87.3 9.0 1e-24 87.1 9.0 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit HrpE PF06188.12 CDJ63348.1 - 0.23 11.3 4.2 0.46 10.3 4.2 1.4 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E ATP-synt_B PF00430.18 CDJ63348.1 - 0.27 11.3 11.4 0.12 12.4 8.9 1.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) PEP-utilisers_N PF05524.13 CDJ63348.1 - 0.49 10.6 5.7 0.71 10.1 5.7 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal WD40 PF00400.32 CDJ63349.1 - 3e-22 78.5 18.6 2.4e-05 25.0 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ63349.1 - 3e-07 30.6 0.0 0.64 10.3 0.0 4.9 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S5 PF00333.20 CDJ63350.1 - 4.1e-30 103.6 0.6 9.5e-30 102.4 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CDJ63350.1 - 4.8e-23 80.4 0.0 9.1e-23 79.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain BAG6 PF12057.8 CDJ63351.1 - 0.037 13.7 0.1 5.3 6.7 0.0 2.6 1 1 1 2 2 2 0 BCL2-associated athanogene 6 PRP1_N PF06424.12 CDJ63352.1 - 7.6e-53 178.9 2.6 2.1e-43 148.2 0.6 3.0 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CDJ63352.1 - 1.8e-29 99.9 31.4 0.0011 19.7 0.4 15.1 5 3 9 15 15 15 8 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ63352.1 - 3.9e-19 68.9 13.6 0.00042 20.8 0.2 9.4 7 3 2 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ63352.1 - 1e-07 32.4 17.1 0.00026 21.6 0.0 8.6 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ63352.1 - 8.7e-06 25.6 3.0 12 6.4 0.0 7.5 8 1 1 9 9 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ63352.1 - 4.1e-05 23.4 19.4 5.1 7.5 0.2 10.2 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ63352.1 - 5.6e-05 23.2 5.4 11 6.6 0.0 9.4 11 2 1 12 12 11 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ63352.1 - 6.6e-05 22.5 0.3 1.7 8.4 0.0 4.8 4 0 0 4 4 4 2 TPR repeat ANAPC3 PF12895.7 CDJ63352.1 - 8.9e-05 22.6 6.1 0.22 11.8 0.3 5.5 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDJ63352.1 - 0.0011 19.2 11.0 1.5 9.1 0.2 7.0 6 1 1 7 7 7 1 Tetratricopeptide repeat Suf PF05843.14 CDJ63352.1 - 0.002 18.1 0.2 17 5.3 0.1 4.8 4 2 1 5 5 5 0 Suppressor of forked protein (Suf) ChAPs PF09295.10 CDJ63352.1 - 0.0021 17.1 8.3 0.66 8.9 0.1 4.1 2 1 2 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) DUF3808 PF10300.9 CDJ63352.1 - 0.0025 16.6 2.9 0.69 8.6 0.1 4.2 4 1 1 5 5 5 1 Protein of unknown function (DUF3808) TPR_9 PF13371.6 CDJ63352.1 - 0.028 14.6 8.5 0.55 10.4 0.1 5.4 5 1 1 6 6 5 0 Tetratricopeptide repeat HHH PF00633.23 CDJ63352.1 - 0.035 14.0 0.3 0.21 11.5 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif TPR_21 PF09976.9 CDJ63352.1 - 0.061 13.0 14.6 0.014 15.1 3.3 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain SCAN PF02023.17 CDJ63352.1 - 0.077 12.8 4.1 1.9 8.4 0.1 3.9 2 1 1 3 3 3 0 SCAN domain TPR_6 PF13174.6 CDJ63352.1 - 0.12 13.0 12.8 32 5.5 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ63352.1 - 0.45 10.4 1.7 3.5 7.6 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 CDJ63353.1 - 3e-39 135.6 0.5 2.1e-28 99.8 0.0 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ63353.1 - 2.5e-12 46.8 0.2 8.2e-12 45.2 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDJ63353.1 - 1.8e-06 27.3 3.6 1.8e-06 27.3 3.6 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 CDJ63353.1 - 3.6e-06 26.6 0.2 8.6e-06 25.3 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDJ63353.1 - 9e-06 25.1 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDJ63353.1 - 3.7e-05 23.5 2.6 3.9e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CDJ63353.1 - 0.00016 21.1 0.3 0.00031 20.1 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CDJ63353.1 - 0.00079 18.7 0.1 0.0016 17.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CDJ63353.1 - 0.0013 19.2 0.3 0.0034 17.9 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ63353.1 - 0.0031 16.3 0.8 0.0031 16.3 0.8 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 CDJ63353.1 - 0.0041 16.4 1.5 0.011 14.9 1.5 1.8 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CDJ63353.1 - 0.0082 15.3 1.9 0.014 14.5 1.9 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A PHD PF00628.29 CDJ63353.1 - 0.099 12.6 7.9 0.014 15.2 1.3 2.9 3 0 0 3 3 3 0 PHD-finger Epimerase PF01370.21 CDJ63354.1 - 1.9e-26 93.0 0.1 4.9e-24 85.1 0.0 2.0 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ63354.1 - 3e-21 76.2 0.1 2.6e-19 69.8 0.0 2.0 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDJ63354.1 - 1.1e-08 34.4 0.0 1.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CDJ63354.1 - 2.6e-06 26.8 0.1 2.5e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CDJ63354.1 - 3.9e-06 26.2 0.7 9.5e-06 24.9 0.8 1.7 1 1 1 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CDJ63354.1 - 3.6e-05 23.1 0.1 0.00034 19.9 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 CDJ63354.1 - 0.00013 22.0 0.2 0.00018 21.5 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Ribosomal_60s PF00428.19 CDJ63354.1 - 0.011 16.3 8.8 0.024 15.2 7.7 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein XPC-binding PF09280.11 CDJ63354.1 - 0.014 15.1 2.2 0.6 9.9 1.5 2.4 2 0 0 2 2 2 0 XPC-binding domain F-box-like PF12937.7 CDJ63355.1 - 0.0054 16.6 0.6 0.0054 16.6 0.6 2.3 3 0 0 3 3 3 1 F-box-like Ribosomal_60s PF00428.19 CDJ63355.1 - 0.0095 16.5 4.3 0.0095 16.5 4.3 5.2 5 0 0 5 5 5 2 60s Acidic ribosomal protein DUF4667 PF15700.5 CDJ63355.1 - 0.016 15.4 0.7 0.016 15.4 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4667) CCDC24 PF15669.5 CDJ63355.1 - 0.029 14.2 0.6 0.029 14.2 0.6 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 24 family Penaeidin PF05927.11 CDJ63355.1 - 0.037 14.8 1.4 0.037 14.8 1.4 3.1 3 0 0 3 3 3 0 Penaeidin SR-25 PF10500.9 CDJ63355.1 - 1.3 8.5 43.5 0.17 11.5 17.4 3.0 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 CDJ63355.1 - 3.5 7.4 14.6 1.6 8.6 2.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) DUF1765 PF08578.10 CDJ63356.1 - 1.4e-11 44.9 0.2 2.7e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Sugar_transport PF06800.12 CDJ63356.1 - 0.017 14.5 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 Sugar transport protein SUIM_assoc PF16619.5 CDJ63356.1 - 0.029 14.4 0.4 0.029 14.4 0.4 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SurA_N_3 PF13624.6 CDJ63356.1 - 0.054 13.3 0.2 0.054 13.3 0.2 2.3 2 0 0 2 2 2 0 SurA N-terminal domain DUF4834 PF16118.5 CDJ63356.1 - 0.33 11.9 0.1 0.33 11.9 0.1 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) DUF2195 PF09961.9 CDJ63356.1 - 1 9.4 3.9 8.2 6.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2195) PilM PF07419.12 CDJ63356.1 - 8.8 6.5 7.8 0.64 10.2 0.3 2.4 2 0 0 2 2 2 0 PilM TMEM208_SND2 PF05620.11 CDJ63356.1 - 9.1 6.0 13.9 0.45 10.3 0.2 3.5 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 F-box-like PF12937.7 CDJ63357.1 - 2e-06 27.6 3.9 0.024 14.5 0.1 2.3 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 CDJ63357.1 - 0.011 15.6 0.2 2.4 8.1 0.1 2.3 2 0 0 2 2 2 0 F-box domain F-box_5 PF18511.1 CDJ63357.1 - 0.2 11.3 1.8 4.5 6.9 0.2 2.3 2 0 0 2 2 2 0 F-box DUF2207 PF09972.9 CDJ63358.1 - 0.0039 16.0 1.0 0.0045 15.8 1.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Methyltransf_16 PF10294.9 CDJ63358.1 - 0.048 13.4 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DHHC PF01529.20 CDJ63358.1 - 0.66 10.1 4.1 0.86 9.7 4.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF677 PF05055.12 CDJ63359.1 - 0.0011 18.0 0.2 0.0011 18.0 0.2 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF677) Arr-ms PF12120.8 CDJ63359.1 - 0.0074 16.5 9.8 0.2 11.9 0.0 3.3 1 1 2 3 3 3 2 Rifampin ADP-ribosyl transferase Nup54_C PF18437.1 CDJ63359.1 - 0.045 13.7 8.9 3.7 7.5 0.0 3.3 3 0 0 3 3 3 0 Nup54 C-terminal interacting domain JIP_LZII PF16471.5 CDJ63359.1 - 0.1 12.8 2.3 0.19 12.0 2.3 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II GIT_CC PF16559.5 CDJ63359.1 - 0.13 12.1 6.2 0.3 11.0 6.2 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cyto_heme_lyase PF01265.17 CDJ63359.1 - 0.17 11.5 1.7 0.26 10.8 1.7 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase YueH PF14166.6 CDJ63359.1 - 0.22 11.4 1.0 0.47 10.4 1.0 1.5 1 0 0 1 1 1 0 YueH-like protein TFIIA PF03153.13 CDJ63359.1 - 1.3 9.0 9.5 1.4 8.9 9.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ST7 PF04184.12 CDJ63359.1 - 1.4 7.3 6.2 1.9 6.8 6.2 1.1 1 0 0 1 1 1 0 ST7 protein SAE2 PF08573.10 CDJ63359.1 - 2.3 9.3 4.9 5.8 8.1 4.9 1.6 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF3450 PF11932.8 CDJ63359.1 - 3.3 6.9 15.3 6.2 6.1 15.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SR-25 PF10500.9 CDJ63360.1 - 0.0021 17.7 1.0 0.0021 17.7 1.0 13.1 10 4 4 14 14 14 1 Nuclear RNA-splicing-associated protein DUF3675 PF12428.8 CDJ63361.1 - 0.00077 20.0 1.2 0.0011 19.5 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3675) Phage_GPO PF05929.11 CDJ63361.1 - 0.0038 16.9 12.2 0.0061 16.2 12.2 1.2 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase Synaptobrevin PF00957.21 CDJ63361.1 - 0.018 14.8 0.3 0.032 14.0 0.3 1.3 1 0 0 1 1 1 0 Synaptobrevin SNARE PF05739.19 CDJ63361.1 - 0.13 12.3 4.3 0.35 10.9 4.0 2.0 1 1 0 1 1 1 0 SNARE domain DUF4407 PF14362.6 CDJ63361.1 - 0.13 11.6 8.8 0.1 11.9 7.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2207 PF09972.9 CDJ63361.1 - 0.23 10.2 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sipho_Gp157 PF05565.11 CDJ63361.1 - 0.25 11.4 8.0 0.38 10.7 8.0 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 DUF1664 PF07889.12 CDJ63361.1 - 2.4 8.2 8.3 4 7.5 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MCU PF04678.13 CDJ63361.1 - 3.2 7.8 9.4 3 7.9 6.7 2.0 2 1 1 3 3 3 0 Mitochondrial calcium uniporter Pup PF05639.11 CDJ63361.1 - 3.4 8.6 13.3 1.1 10.2 4.3 2.5 2 0 0 2 2 2 0 Pup-like protein Pkinase PF00069.25 CDJ63363.1 - 8.7e-64 215.4 0.3 2.7e-63 213.8 0.3 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63363.1 - 7.6e-38 130.3 0.3 8e-28 97.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_7 PF13499.6 CDJ63363.1 - 5e-33 113.4 0.5 1.7e-11 44.4 0.0 4.6 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 CDJ63363.1 - 5.2e-33 110.1 3.7 1.8e-06 27.1 0.0 6.5 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 CDJ63363.1 - 9.3e-29 96.9 4.2 4.9e-05 22.9 0.0 6.6 6 0 0 6 6 6 5 EF-hand domain EF-hand_5 PF13202.6 CDJ63363.1 - 9.3e-27 91.3 8.8 3.9e-07 29.3 0.0 6.7 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.6 CDJ63363.1 - 1.3e-20 73.0 5.6 3.1e-05 23.7 0.0 5.8 3 3 3 6 6 6 5 EF-hand domain pair EF-hand_4 PF12763.7 CDJ63363.1 - 1.1e-06 28.6 1.1 0.06 13.3 0.0 3.4 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 CDJ63363.1 - 1.8e-06 27.4 0.0 3.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.9 CDJ63363.1 - 2.3e-06 27.9 4.1 0.0082 16.5 0.0 3.2 4 0 0 4 4 3 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 CDJ63363.1 - 0.00023 20.6 0.6 0.0054 16.1 0.6 2.2 1 1 0 1 1 1 1 Kinase-like EF-hand_9 PF14658.6 CDJ63363.1 - 0.00078 19.7 0.0 2.4 8.5 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain APH PF01636.23 CDJ63363.1 - 0.0047 16.9 0.0 0.26 11.2 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family SUIM_assoc PF16619.5 CDJ63363.1 - 0.016 15.3 1.2 0.016 15.3 1.2 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 EF-hand_10 PF14788.6 CDJ63363.1 - 0.021 14.7 0.1 26 4.8 0.0 4.4 4 1 1 5 5 5 0 EF hand Choline_kinase PF01633.20 CDJ63363.1 - 0.062 12.9 0.2 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Dockerin_1 PF00404.18 CDJ63363.1 - 0.083 13.1 0.5 2.9e+02 1.7 0.0 4.5 4 1 0 4 4 4 0 Dockerin type I domain PDH PF02153.17 CDJ63363.1 - 0.12 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase SR-25 PF10500.9 CDJ63364.1 - 0.0008 19.1 23.4 0.0008 19.1 23.4 4.3 2 1 2 4 4 4 2 Nuclear RNA-splicing-associated protein DAP3 PF10236.9 CDJ63366.1 - 2.3e-05 23.7 0.0 0.00066 18.9 0.0 2.6 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 Sec8_exocyst PF04048.14 CDJ63366.1 - 0.16 11.8 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain PA14 PF07691.12 CDJ63367.1 - 9.2e-19 67.7 0.0 8.9e-15 54.8 0.0 2.4 2 0 0 2 2 2 2 PA14 domain GLEYA PF10528.9 CDJ63367.1 - 0.17 12.3 0.0 0.51 10.8 0.0 1.9 1 0 0 1 1 1 0 GLEYA domain Mucin-like PF16058.5 CDJ63367.1 - 0.68 10.0 20.8 1.2 9.2 20.8 1.4 1 0 0 1 1 1 0 Mucin-like DUF2151 PF10221.9 CDJ63367.1 - 1.5 7.3 8.6 36 2.8 0.0 2.2 2 0 0 2 2 2 0 Cell cycle and development regulator FAM104 PF15434.6 CDJ63368.1 - 0.74 10.4 28.6 5.7 7.5 7.0 3.2 2 0 0 2 2 2 0 Family 104 Cullin PF00888.22 CDJ63369.1 - 3.1e-53 181.4 0.0 2.5e-29 102.4 0.1 3.9 1 1 2 3 3 3 3 Cullin family AF-4 PF05110.13 CDJ63369.1 - 0.81 7.7 3.4 1.1 7.2 3.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SUIM_assoc PF16619.5 CDJ63370.1 - 0.004 17.2 0.0 0.004 17.2 0.0 14.7 3 3 4 7 7 7 1 Unstructured region C-term to UIM in Ataxin3 Pentapeptide_4 PF13599.6 CDJ63370.1 - 0.39 10.9 2.0 1.9 8.7 0.3 2.1 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) SR-25 PF10500.9 CDJ63371.1 - 0.0038 16.9 1.3 0.0052 16.4 1.3 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ63371.1 - 0.71 10.2 15.1 3.9 7.7 15.1 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ63372.1 - 0.0001 22.5 39.2 0.00072 19.7 31.2 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ63372.1 - 0.0053 16.8 1.1 0.0053 16.8 1.1 5.2 2 1 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 DDHD PF02862.17 CDJ63372.1 - 0.07 13.3 12.0 0.069 13.3 9.2 2.0 2 0 0 2 2 2 0 DDHD domain Pex14_N PF04695.13 CDJ63372.1 - 0.099 13.3 25.6 0.52 10.9 19.5 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4746 PF15928.5 CDJ63372.1 - 0.19 11.2 14.9 0.36 10.2 14.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) WDCP PF15390.6 CDJ63372.1 - 0.35 9.2 8.7 0.47 8.8 8.7 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Exonuc_VII_L PF02601.15 CDJ63372.1 - 0.7 9.4 20.1 0.33 10.5 16.1 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit CCDC53 PF10152.9 CDJ63372.1 - 1.4 9.4 20.5 1.4 9.4 15.3 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Velvet PF11754.8 CDJ63372.1 - 1.8 8.5 14.1 1.7 8.5 11.7 1.9 2 0 0 2 2 2 0 Velvet factor MPM1 PF17234.2 CDJ63372.1 - 2.8 8.2 16.5 0.18 12.0 10.5 2.0 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 GREB1 PF15782.5 CDJ63372.1 - 3.3 4.7 13.1 4.5 4.3 13.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_11 PF13086.6 CDJ63372.1 - 3.9 7.2 18.4 1.4 8.6 15.6 1.6 2 0 0 2 2 2 0 AAA domain SID-1_RNA_chan PF13965.6 CDJ63372.1 - 4.4 5.6 4.9 5.7 5.2 4.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PRP1_N PF06424.12 CDJ63372.1 - 4.5 7.7 18.3 4 7.8 15.8 2.0 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Asp-B-Hydro_N PF05279.11 CDJ63372.1 - 6 6.9 17.2 11 6.0 17.2 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAT1 PF09770.9 CDJ63372.1 - 6.7 4.8 33.3 0.97 7.6 27.1 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 BORG_CEP PF14957.6 CDJ63372.1 - 9.4 7.4 13.4 8.5 7.6 11.2 2.0 2 0 0 2 2 2 0 Cdc42 effector Neur_chan_memb PF02932.16 CDJ63372.1 - 9.7 6.2 18.0 18 5.3 16.4 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Hydrolase_4 PF12146.8 CDJ63373.1 - 3.2e-20 72.4 0.0 3.2e-13 49.5 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ63373.1 - 8.2e-12 45.3 2.1 6.1e-08 32.6 0.0 2.9 2 2 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ63373.1 - 3.4e-09 37.6 0.1 9e-09 36.3 0.0 1.6 2 1 0 2 2 1 1 Alpha/beta hydrolase family DLH PF01738.18 CDJ63373.1 - 5.8e-08 32.6 0.0 3.1e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CDJ63373.1 - 1.8e-07 30.9 0.0 3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 CDJ63373.1 - 5.1e-06 25.4 0.0 0.00054 18.7 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 CDJ63373.1 - 7.6e-06 25.7 2.3 0.0079 15.8 0.0 3.2 2 2 0 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 CDJ63373.1 - 9.6e-06 25.7 0.0 0.01 15.8 0.0 2.3 1 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 CDJ63373.1 - 1.4e-05 24.9 0.1 0.00019 21.2 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Esterase PF00756.20 CDJ63373.1 - 2.4e-05 24.1 0.0 4.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 CDJ63373.1 - 0.00012 21.9 0.0 0.026 14.3 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CDJ63373.1 - 0.00031 20.6 0.0 0.053 13.3 0.0 2.3 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase DUF818 PF05677.12 CDJ63373.1 - 0.00046 19.2 0.0 0.0007 18.7 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Thioesterase PF00975.20 CDJ63373.1 - 0.00057 20.1 0.0 0.002 18.3 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain DUF1057 PF06342.12 CDJ63373.1 - 0.00059 19.0 0.0 0.02 13.9 0.0 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 CDJ63373.1 - 0.0024 17.8 0.0 0.0068 16.3 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 CDJ63373.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 CDJ63373.1 - 0.015 15.2 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LIP PF03583.14 CDJ63373.1 - 0.016 14.5 3.5 0.77 9.0 0.0 3.2 2 1 1 3 3 3 0 Secretory lipase DUF2974 PF11187.8 CDJ63373.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LIDHydrolase PF10230.9 CDJ63373.1 - 0.05 13.1 0.0 1.1 8.7 0.0 2.1 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase UPF0227 PF05728.12 CDJ63373.1 - 0.17 11.8 0.0 0.44 10.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Apt1 PF10351.9 CDJ63373.1 - 0.29 9.9 6.3 0.44 9.3 6.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPRY PF00622.28 CDJ63374.1 - 0.00085 19.4 0.0 0.0075 16.4 0.0 2.1 1 1 0 1 1 1 1 SPRY domain TAFII55_N PF04658.13 CDJ63375.1 - 1e-16 61.1 0.0 1e-16 61.1 0.0 3.6 4 1 0 4 4 4 1 TAFII55 protein conserved region TFIIA PF03153.13 CDJ63375.1 - 0.2 11.6 50.1 0.15 12.0 13.2 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Hydrolase_4 PF12146.8 CDJ63378.1 - 9.4e-14 51.2 0.0 1.7e-08 34.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ63378.1 - 4.7e-11 42.8 0.0 7.6e-06 25.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 CDJ63378.1 - 1.8e-07 30.2 0.0 0.0045 15.7 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 CDJ63378.1 - 7.2e-06 25.6 0.0 1.5e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CDJ63378.1 - 1.5e-05 25.7 0.0 3.9e-05 24.4 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CDJ63378.1 - 0.00019 21.2 0.0 0.001 18.7 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 CDJ63378.1 - 0.00041 20.0 0.0 0.0025 17.4 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CDJ63378.1 - 0.00089 19.2 0.0 0.0019 18.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 CDJ63378.1 - 0.002 17.8 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.12 CDJ63378.1 - 0.0045 16.0 0.0 0.0061 15.6 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.11 CDJ63378.1 - 0.0051 16.7 0.0 0.057 13.3 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 CDJ63378.1 - 0.0079 16.0 0.0 0.049 13.4 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 CDJ63378.1 - 0.0094 15.5 0.0 0.19 11.3 0.0 2.3 1 1 1 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 CDJ63378.1 - 0.17 11.6 0.0 1.5 8.6 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Flagellin_N PF00669.20 CDJ63379.1 - 3 8.0 5.0 1.1 9.4 0.6 2.4 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region LRR_8 PF13855.6 CDJ63379.1 - 4.2 7.2 4.5 9.3 6.1 0.0 3.5 4 1 0 4 4 4 0 Leucine rich repeat TMEM192 PF14802.6 CDJ63382.1 - 0.063 12.4 1.1 0.085 11.9 1.1 1.3 1 0 0 1 1 1 0 TMEM192 family V_ATPase_I PF01496.19 CDJ63382.1 - 3.4 5.5 7.8 4 5.2 7.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMCO5 PF14992.6 CDJ63383.1 - 0.0021 17.7 13.1 0.0025 17.4 13.1 1.1 1 0 0 1 1 1 1 TMCO5 family SlyX PF04102.12 CDJ63383.1 - 0.005 17.4 9.8 0.005 17.4 9.8 3.0 1 1 1 2 2 2 1 SlyX BRE1 PF08647.11 CDJ63383.1 - 0.042 13.9 17.1 0.057 13.5 17.1 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 CDJ63383.1 - 0.062 13.4 25.8 0.079 13.0 25.8 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tli4_C PF18426.1 CDJ63383.1 - 0.071 13.4 4.0 0.087 13.1 4.0 1.1 1 0 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain Spc7 PF08317.11 CDJ63383.1 - 0.09 11.6 21.8 0.15 10.9 21.8 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 CDJ63383.1 - 0.093 12.3 14.8 0.096 12.2 14.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 CDJ63383.1 - 0.21 11.9 22.4 0.31 11.4 22.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PV-1 PF06637.11 CDJ63383.1 - 0.24 10.2 17.7 0.34 9.7 17.7 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Atg14 PF10186.9 CDJ63383.1 - 0.35 9.9 15.5 0.53 9.3 15.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RRP36 PF06102.12 CDJ63383.1 - 0.37 10.7 13.9 0.45 10.5 13.9 1.1 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF4200 PF13863.6 CDJ63383.1 - 0.45 10.9 22.5 0.76 10.2 22.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3584 PF12128.8 CDJ63383.1 - 0.57 7.6 19.9 0.66 7.4 19.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FAM117 PF15388.6 CDJ63383.1 - 0.62 9.4 9.8 0.77 9.1 9.8 1.0 1 0 0 1 1 1 0 Protein Family FAM117 DUF3138 PF11336.8 CDJ63383.1 - 0.64 8.6 10.8 0.75 8.3 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) HMMR_N PF15905.5 CDJ63383.1 - 0.76 9.2 21.7 15 4.9 21.7 2.0 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DOR PF14839.6 CDJ63383.1 - 0.91 9.4 13.8 1.1 9.1 13.8 1.2 1 0 0 1 1 1 0 DOR family V_ATPase_I PF01496.19 CDJ63383.1 - 0.92 7.4 11.9 1 7.2 11.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tam41_Mmp37 PF09139.11 CDJ63383.1 - 0.97 8.8 7.2 1.1 8.6 7.2 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial IFT20 PF14931.6 CDJ63383.1 - 1.2 9.3 21.2 0.14 12.4 9.6 2.4 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DASH_Spc19 PF08287.11 CDJ63383.1 - 1.4 8.8 17.7 1.7 8.5 17.7 1.1 1 0 0 1 1 1 0 Spc19 DUF16 PF01519.16 CDJ63383.1 - 1.5 9.4 19.8 1.8 9.1 8.8 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4407 PF14362.6 CDJ63383.1 - 1.6 8.0 21.1 1.8 7.9 21.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 CDJ63383.1 - 1.7 7.1 19.8 2 6.9 19.8 1.0 1 0 0 1 1 1 0 Macoilin family DUF724 PF05266.14 CDJ63383.1 - 1.7 8.4 14.3 2.1 8.1 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Bud13 PF09736.9 CDJ63383.1 - 2.1 8.8 14.1 2.7 8.4 14.1 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Peptidase_S66 PF02016.15 CDJ63383.1 - 2.5 8.2 4.5 2.4 8.3 2.2 1.9 1 1 1 2 2 2 0 LD-carboxypeptidase N-terminal domain HDAC4_Gln PF12203.8 CDJ63383.1 - 3.1 8.0 29.7 1.6 9.0 17.4 2.1 1 1 1 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 ADIP PF11559.8 CDJ63383.1 - 3.3 7.8 24.4 0.38 10.8 7.4 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4192 PF13830.6 CDJ63383.1 - 3.7 7.5 13.2 4.2 7.4 13.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF3450 PF11932.8 CDJ63383.1 - 4 6.7 25.9 29 3.9 25.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) HAUS6_N PF14661.6 CDJ63383.1 - 4.9 6.7 14.5 6.5 6.3 14.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus XRN_M PF17846.1 CDJ63383.1 - 5.9 5.7 9.5 6.5 5.6 9.5 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Cob_adeno_trans PF01923.18 CDJ63383.1 - 6 7.0 10.1 12 6.0 10.1 1.5 1 1 0 1 1 1 0 Cobalamin adenosyltransferase UPF0242 PF06785.11 CDJ63383.1 - 6.4 6.8 19.3 8.4 6.5 19.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Phage_GPO PF05929.11 CDJ63383.1 - 7.4 6.1 18.8 16 5.0 18.5 1.5 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase USP8_interact PF08941.10 CDJ63383.1 - 7.4 6.3 16.4 2 8.2 9.5 2.1 1 1 1 2 2 2 0 USP8 interacting CENP-Q PF13094.6 CDJ63383.1 - 8.6 6.5 22.5 49 4.1 22.6 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit AIF-MLS PF14962.6 CDJ63383.1 - 9.3 6.2 10.7 12 5.9 10.7 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Pkinase PF00069.25 CDJ63384.1 - 5.3e-44 150.6 0.1 1.3e-43 149.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63384.1 - 4.1e-20 72.2 1.7 8.8e-20 71.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase TFIIA PF03153.13 CDJ63384.1 - 0.017 15.1 23.1 0.29 11.1 12.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 CDJ63384.1 - 0.041 13.1 16.0 0.58 9.3 4.8 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 CDJ63384.1 - 0.62 9.6 24.7 1 8.9 8.0 2.3 2 0 0 2 2 2 0 Spt20 family Peptidase_C48 PF02902.19 CDJ63385.1 - 3.4e-17 63.0 0.4 2.6e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain DUF1645 PF07816.11 CDJ63385.1 - 0.0074 16.9 7.6 0.0074 16.9 7.6 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1645) Sporozoite_P67 PF05642.11 CDJ63385.1 - 0.023 12.8 0.0 0.023 12.8 0.0 1.8 2 1 0 2 2 2 0 Sporozoite P67 surface antigen CM_1 PF07736.11 CDJ63386.1 - 0.14 12.6 1.2 0.39 11.1 1.2 1.8 1 0 0 1 1 1 0 Chorismate mutase type I Presenilin PF01080.17 CDJ63386.1 - 0.32 9.7 8.3 0.049 12.4 2.8 2.1 2 0 0 2 2 2 0 Presenilin SPX PF03105.19 CDJ63386.1 - 0.45 10.4 11.7 2.3 8.1 11.7 2.0 1 1 0 1 1 1 0 SPX domain Glt_symporter PF03616.14 CDJ63386.1 - 1.1 7.9 5.3 0.12 11.1 0.4 1.8 2 0 0 2 2 2 0 Sodium/glutamate symporter RAP1 PF07218.11 CDJ63386.1 - 6.5 4.9 12.5 9.1 4.4 12.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RskA PF10099.9 CDJ63388.1 - 9.8e-05 22.7 6.5 9.8e-05 22.7 6.5 20.6 2 2 16 18 18 18 2 Anti-sigma-K factor rskA Gp_dh_C PF02800.20 CDJ63389.1 - 1e-54 184.4 0.0 2.5e-39 134.4 0.0 2.4 1 1 1 2 2 2 2 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CDJ63389.1 - 4.1e-34 116.9 0.0 9.2e-34 115.8 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF4799 PF16056.5 CDJ63389.1 - 7.8e-06 25.3 0.7 7.8e-06 25.3 0.7 1.6 2 0 0 2 2 1 1 Domain of unknown function (DUF4799) Roughex PF06020.11 CDJ63389.1 - 0.033 13.3 6.5 0.062 12.4 6.5 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Pox_A12 PF04651.13 CDJ63389.1 - 0.071 13.2 2.8 0.14 12.2 2.8 1.5 1 0 0 1 1 1 0 Poxvirus A12 protein DDHD PF02862.17 CDJ63389.1 - 0.086 13.0 3.6 2.3 8.3 0.7 2.3 2 0 0 2 2 2 0 DDHD domain 2-Hacid_dh_C PF02826.19 CDJ63389.1 - 0.096 12.0 0.0 0.096 12.0 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3947 PF13135.6 CDJ63389.1 - 0.1 12.8 6.4 0.27 11.4 6.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) DapB_N PF01113.20 CDJ63389.1 - 0.24 11.5 1.6 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF2072 PF09845.9 CDJ63389.1 - 0.28 11.4 1.0 0.68 10.2 1.0 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein TFIIA PF03153.13 CDJ63389.1 - 0.64 10.0 19.1 0.25 11.3 15.7 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 CDJ63389.1 - 1 8.7 2.4 2.9 7.2 0.1 2.3 2 1 0 2 2 2 0 Plasmodium vivax Vir protein DUF4667 PF15700.5 CDJ63389.1 - 2.2 8.3 14.1 0.95 9.5 6.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Pex14_N PF04695.13 CDJ63389.1 - 3.9 8.1 17.3 13 6.4 11.4 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apt1 PF10351.9 CDJ63389.1 - 7.4 5.3 7.9 2 7.2 1.8 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain PRP3 PF08572.10 CDJ63390.1 - 6.5e-10 39.1 11.1 6.5e-10 39.1 11.1 4.6 4 1 0 4 4 4 1 pre-mRNA processing factor 3 (PRP3) SUIM_assoc PF16619.5 CDJ63390.1 - 4.6 7.4 0.0 4.6 7.4 0.0 8.6 3 3 4 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 Neur_chan_memb PF02932.16 CDJ63391.1 - 0.99 9.4 17.8 0.97 9.4 6.6 3.7 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF3464 PF11947.8 CDJ63391.1 - 6.8 6.4 14.9 0.52 10.1 7.0 3.0 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 SR-25 PF10500.9 CDJ63392.1 - 0.0067 16.1 40.8 0.0067 16.1 40.8 2.4 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 CDJ63392.1 - 0.021 15.3 20.7 0.029 14.9 20.7 1.1 1 0 0 1 1 1 0 AAA domain SprA-related PF12118.8 CDJ63392.1 - 0.046 12.9 54.4 0.075 12.2 54.4 1.3 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.13 CDJ63392.1 - 1.8 8.5 44.9 2.1 8.2 44.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 CDJ63392.1 - 2 7.9 30.3 2.7 7.5 30.3 1.1 1 0 0 1 1 1 0 PPP4R2 PAT1 PF09770.9 CDJ63392.1 - 2.5 6.2 32.6 3.2 5.9 32.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.13 CDJ63392.1 - 3.5 6.1 30.3 4.5 5.7 30.3 1.2 1 0 0 1 1 1 0 Utp14 protein Serinc PF03348.15 CDJ63392.1 - 5.8 5.7 20.0 9 5.1 20.0 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hamartin PF04388.12 CDJ63392.1 - 9.2 4.8 40.9 12 4.5 40.9 1.0 1 0 0 1 1 1 0 Hamartin protein GCS PF03074.16 CDJ63393.1 - 6.1e-101 338.4 0.1 2.8e-54 184.9 0.0 3.6 2 1 0 3 3 3 3 Glutamate-cysteine ligase SUIM_assoc PF16619.5 CDJ63393.1 - 0.034 14.2 0.5 0.034 14.2 0.5 3.8 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ63394.1 - 0.25 10.9 15.2 0.34 10.5 15.2 1.2 1 0 0 1 1 1 0 Spt20 family Otopetrin PF03189.13 CDJ63394.1 - 0.25 10.1 1.6 0.29 9.9 1.6 1.0 1 0 0 1 1 1 0 Otopetrin Apt1 PF10351.9 CDJ63394.1 - 0.28 10.0 4.3 0.25 10.2 4.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NST1 PF13945.6 CDJ63394.1 - 0.35 10.9 10.3 0.48 10.5 10.3 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator NPR3 PF03666.13 CDJ63394.1 - 0.36 9.6 6.7 0.36 9.6 6.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM199X PF15814.5 CDJ63394.1 - 0.43 9.6 21.9 0.6 9.1 21.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X Lin-8 PF03353.15 CDJ63394.1 - 0.55 9.7 9.5 0.77 9.3 9.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SOG2 PF10428.9 CDJ63394.1 - 0.56 9.3 13.9 0.6 9.2 13.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CDJ63394.1 - 2.3 6.9 9.8 2.6 6.7 9.8 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ63394.1 - 2.6 6.7 14.4 2.7 6.5 14.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF966 PF06136.13 CDJ63394.1 - 2.9 7.5 14.3 3.5 7.3 14.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SRP-alpha_N PF04086.13 CDJ63394.1 - 3.6 7.4 16.1 4.6 7.1 16.1 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SUIM_assoc PF16619.5 CDJ63394.1 - 4 7.6 18.4 9 6.5 18.4 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ63394.1 - 4.9 6.7 26.0 3.3 7.2 18.7 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.13 CDJ63394.1 - 6.3 5.7 16.0 7.6 5.5 16.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Atrophin-1 PF03154.15 CDJ63394.1 - 7.5 4.7 16.8 9.3 4.4 16.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family Roughex PF06020.11 CDJ63394.1 - 7.8 5.5 10.0 9.9 5.1 10.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF5427 PF10310.9 CDJ63394.1 - 8.7 5.2 25.2 10 4.9 25.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Peptidase_S64 PF08192.11 CDJ63394.1 - 8.8 4.7 8.7 8.5 4.7 8.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 NuA4 PF09340.10 CDJ63395.1 - 1.4e-18 66.5 0.0 4.7e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Herpes_US12 PF05363.12 CDJ63395.1 - 0.00054 20.6 0.2 0.0015 19.2 0.2 1.8 1 0 0 1 1 1 1 Herpesvirus US12 family Histone_HNS PF00816.21 CDJ63395.1 - 0.26 12.2 0.1 0.26 12.2 0.1 3.2 3 1 0 3 3 3 0 H-NS histone family OPA3 PF07047.12 CDJ63396.1 - 7.7e-29 100.0 0.3 7.7e-29 100.0 0.3 2.2 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) Spt20 PF12090.8 CDJ63396.1 - 0.0035 17.0 18.8 0.0042 16.7 18.8 1.2 1 0 0 1 1 1 1 Spt20 family RskA PF10099.9 CDJ63396.1 - 0.0061 16.9 3.0 0.0071 16.7 3.0 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ63396.1 - 0.021 14.8 16.7 0.025 14.6 16.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ctr PF04145.15 CDJ63396.1 - 0.032 14.9 0.6 0.035 14.7 0.6 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF2722 PF10846.8 CDJ63396.1 - 0.048 12.6 17.6 0.058 12.3 17.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ63396.1 - 0.092 11.4 18.4 0.11 11.2 18.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.15 CDJ63396.1 - 0.12 11.3 1.0 0.14 11.1 1.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DcuA_DcuB PF03605.14 CDJ63396.1 - 0.19 10.6 1.5 0.24 10.2 1.5 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter EIIBC-GUT_N PF03612.14 CDJ63396.1 - 0.26 11.0 2.5 0.37 10.5 2.5 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 CDJ63396.1 - 0.4 9.4 5.3 0.48 9.1 5.3 1.1 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 CDJ63396.1 - 0.55 9.2 2.6 0.64 9.0 2.6 1.1 1 0 0 1 1 1 0 CLN3 protein SprA-related PF12118.8 CDJ63396.1 - 0.6 9.2 14.0 0.77 8.8 14.0 1.2 1 0 0 1 1 1 0 SprA-related family RMI1_C PF16099.5 CDJ63396.1 - 1 9.2 9.9 1.5 8.7 9.9 1.2 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold 60KD_IMP PF02096.20 CDJ63396.1 - 1.7 8.5 10.4 2.5 8.0 10.4 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein UPF0560 PF10577.9 CDJ63396.1 - 5.5 5.4 13.5 6.5 5.1 13.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Roughex PF06020.11 CDJ63396.1 - 7.5 5.5 8.8 9.6 5.2 8.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein tRNA_bind PF01588.20 CDJ63398.1 - 7.4e-23 80.5 0.0 1.5e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 CDJ63398.1 - 4.9e-06 26.7 0.0 4.9e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ63398.1 - 5.5e-05 23.3 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ63398.1 - 0.024 14.6 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2722 PF10846.8 CDJ63398.1 - 0.024 13.6 9.7 0.04 12.9 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CPSase_L_D3 PF02787.19 CDJ63398.1 - 0.045 14.1 1.0 0.097 13.0 0.3 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain eIF-3_zeta PF05091.12 CDJ63398.1 - 0.063 12.3 3.7 0.075 12.0 3.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Paf1 PF03985.13 CDJ63398.1 - 0.065 12.2 1.4 0.073 12.1 1.4 1.1 1 0 0 1 1 1 0 Paf1 EPL1 PF10513.9 CDJ63398.1 - 0.073 13.5 1.2 0.1 13.0 1.2 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Mucin PF01456.17 CDJ63398.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.5 2 1 1 3 3 1 0 Mucin-like glycoprotein DDHD PF02862.17 CDJ63398.1 - 0.2 11.8 2.1 0.28 11.3 2.1 1.3 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 CDJ63398.1 - 0.26 11.3 3.9 0.52 10.3 3.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ63398.1 - 1.6 8.7 6.1 2.4 8.1 6.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Macoilin PF09726.9 CDJ63398.1 - 2 6.9 9.5 2.9 6.3 9.5 1.1 1 0 0 1 1 1 0 Macoilin family Mitofilin PF09731.9 CDJ63398.1 - 2.5 6.8 16.5 3.6 6.3 16.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Spt20 PF12090.8 CDJ63398.1 - 4.4 6.8 26.7 0.067 12.8 19.7 1.4 2 0 0 2 2 1 0 Spt20 family TraV PF09676.10 CDJ63398.1 - 4.9 8.1 10.6 9.3 7.2 10.6 1.4 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Phage_Gp15 PF06854.11 CDJ63399.1 - 0.98 9.4 19.2 0.18 11.8 0.4 3.5 3 0 0 3 3 3 0 Bacteriophage Gp15 protein Hydrolase_4 PF12146.8 CDJ63400.1 - 1.7e-13 50.4 0.6 2.2e-12 46.8 0.6 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 CDJ63400.1 - 1.2e-06 27.4 0.0 0.00064 18.5 0.0 2.9 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 CDJ63400.1 - 2.1e-05 24.5 0.1 4.3e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CDJ63400.1 - 9.8e-05 22.1 0.0 0.00024 20.8 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 CDJ63400.1 - 0.0014 18.2 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ63400.1 - 0.002 17.8 0.6 0.056 13.1 0.6 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ63400.1 - 0.0021 18.7 7.1 0.0021 18.7 7.1 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CDJ63400.1 - 0.064 13.1 0.1 0.064 13.1 0.1 1.7 2 0 0 2 2 2 0 Lipase (class 3) MDM1 PF15501.6 CDJ63400.1 - 0.33 10.0 2.9 0.45 9.6 2.9 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 DUF3446 PF11928.8 CDJ63400.1 - 0.6 10.5 12.0 0.13 12.6 7.4 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain Utp14 PF04615.13 CDJ63402.1 - 6.9 5.1 56.0 8.6 4.8 56.0 1.1 1 0 0 1 1 1 0 Utp14 protein 40S_S4_C PF16121.5 CDJ63403.1 - 5.7e-23 80.3 0.4 1.1e-22 79.4 0.3 1.5 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus Ribosomal_S4e PF00900.20 CDJ63403.1 - 9.3e-19 67.1 0.0 2e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal family S4e KOW PF00467.29 CDJ63403.1 - 3.6e-05 23.6 2.1 0.0001 22.1 2.1 1.8 1 0 0 1 1 1 1 KOW motif DUF1635 PF07795.11 CDJ63405.1 - 1.7 8.5 9.1 1.7 8.5 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF2722 PF10846.8 CDJ63406.1 - 0.00097 18.2 5.2 0.0012 17.9 4.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Roughex PF06020.11 CDJ63406.1 - 0.084 12.0 4.6 0.11 11.5 4.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 CDJ63406.1 - 0.19 10.4 2.2 0.27 10.0 2.2 1.2 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ63406.1 - 0.89 9.1 18.5 1.5 8.4 18.5 1.3 1 0 0 1 1 1 0 Spt20 family SARAF PF06682.12 CDJ63406.1 - 4.9 6.7 9.8 9.2 5.8 9.8 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 CDJ63406.1 - 7 7.7 6.2 18 6.4 6.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ63407.1 - 0.52 9.2 2.2 6 5.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF3824 PF12868.7 CDJ63408.1 - 0.078 13.6 1.5 0.078 13.6 1.5 2.5 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) SR-25 PF10500.9 CDJ63408.1 - 1.1 8.9 20.7 1.2 8.7 20.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 CDJ63408.1 - 3.9 8.1 19.6 4.9 7.8 19.6 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain SPX PF03105.19 CDJ63408.1 - 4.5 7.1 12.1 4.6 7.1 12.1 1.0 1 0 0 1 1 1 0 SPX domain Peptidase_M17_N PF02789.17 CDJ63408.1 - 5.2 7.0 14.2 4.6 7.1 13.4 1.4 1 1 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain TMEM151 PF14857.6 CDJ63408.1 - 9.7 5.0 9.3 10 4.9 9.3 1.0 1 0 0 1 1 1 0 TMEM151 family Phage_GPD PF05954.11 CDJ63409.1 - 8.5 5.6 19.4 7.2 5.8 18.4 1.4 1 1 0 1 1 1 0 Phage late control gene D protein (GPD) Ribosomal_L27A PF00828.19 CDJ63411.1 - 1.3e-19 71.1 0.2 6.2e-19 68.9 0.0 2.3 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TFIIA PF03153.13 CDJ63411.1 - 1.3e-05 25.4 49.7 1.3e-05 25.4 49.7 4.5 4 1 1 5 5 5 2 Transcription factor IIA, alpha/beta subunit Mem_trans PF03547.18 CDJ63411.1 - 0.0011 17.4 3.6 0.0014 17.1 0.2 2.3 2 0 0 2 2 2 1 Membrane transport protein Memo PF01875.17 CDJ63412.1 - 2.6e-36 125.2 0.0 6.6e-32 110.7 0.0 2.0 1 1 1 2 2 2 2 Memo-like protein TFIIA PF03153.13 CDJ63414.1 - 1.1 9.2 18.2 1.7 8.5 18.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FmiP_Thoc5 PF09766.9 CDJ63415.1 - 0.53 9.5 7.5 0.98 8.6 7.5 1.3 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Apt1 PF10351.9 CDJ63415.1 - 1.2 7.9 9.6 0.74 8.6 0.9 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain AP2 PF00847.20 CDJ63416.1 - 1.3e-09 38.1 6.3 5.8e-06 26.4 1.4 8.0 8 0 0 8 8 8 4 AP2 domain AUX_IAA PF02309.16 CDJ63416.1 - 1.1 9.0 0.0 1.1 9.0 0.0 7.2 5 3 1 6 6 6 0 AUX/IAA family Ctr PF04145.15 CDJ63417.1 - 6e-12 46.4 4.8 6e-12 46.4 4.8 2.8 2 2 0 2 2 2 1 Ctr copper transporter family V_ATPase_I PF01496.19 CDJ63418.1 - 6.5e-05 21.1 7.1 6.5e-05 21.1 7.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Zip PF02535.22 CDJ63418.1 - 0.0061 15.8 1.8 0.0065 15.7 1.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter XRN_M PF17846.1 CDJ63418.1 - 0.011 14.8 17.5 0.014 14.3 17.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Presenilin PF01080.17 CDJ63418.1 - 0.012 14.5 25.0 0.016 14.0 25.0 1.1 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 CDJ63418.1 - 0.012 14.0 3.3 0.013 13.9 3.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 UPF0565 PF10561.9 CDJ63418.1 - 0.015 14.5 5.7 0.02 14.1 5.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Ndc1_Nup PF09531.10 CDJ63418.1 - 0.028 13.1 14.0 0.032 12.9 14.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAGA-Tad1 PF12767.7 CDJ63418.1 - 0.038 13.7 15.5 0.059 13.1 15.5 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Peptidase_S46 PF10459.9 CDJ63418.1 - 0.046 12.4 14.4 0.052 12.2 14.4 1.1 1 0 0 1 1 1 0 Peptidase S46 SLC12 PF03522.15 CDJ63418.1 - 0.047 12.7 20.9 0.064 12.3 20.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2052 PF09747.9 CDJ63418.1 - 0.063 13.4 24.4 0.089 12.9 24.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NPR3 PF03666.13 CDJ63418.1 - 0.077 11.8 18.8 0.098 11.4 18.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pkinase_fungal PF17667.1 CDJ63418.1 - 0.09 11.5 8.9 0.11 11.2 8.9 1.1 1 0 0 1 1 1 0 Fungal protein kinase MMR1 PF08505.10 CDJ63418.1 - 0.098 12.9 23.6 0.14 12.4 23.6 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FAM76 PF16046.5 CDJ63418.1 - 0.1 11.9 18.1 0.14 11.5 18.1 1.1 1 0 0 1 1 1 0 FAM76 protein WTX PF09422.10 CDJ63418.1 - 0.12 11.4 12.3 0.15 11.1 12.3 1.1 1 0 0 1 1 1 0 WTX protein CCSAP PF15748.5 CDJ63418.1 - 0.13 12.4 23.6 0.18 12.0 23.6 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MRP-S31 PF15433.6 CDJ63418.1 - 0.15 11.7 20.5 0.25 11.0 20.5 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 CDC45 PF02724.14 CDJ63418.1 - 0.19 10.0 19.9 0.24 9.6 19.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Peroxin-3 PF04882.12 CDJ63418.1 - 0.2 10.6 27.5 0.27 10.2 27.5 1.1 1 0 0 1 1 1 0 Peroxin-3 Vfa1 PF08432.10 CDJ63418.1 - 0.27 11.6 21.6 0.43 10.9 21.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Menin PF05053.13 CDJ63418.1 - 0.36 9.1 10.9 0.5 8.7 10.9 1.2 1 0 0 1 1 1 0 Menin DUF4228 PF14009.6 CDJ63418.1 - 0.42 11.0 7.7 0.71 10.2 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) FAM60A PF15396.6 CDJ63418.1 - 0.45 10.5 18.3 0.66 9.9 18.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A AF-4 PF05110.13 CDJ63418.1 - 0.47 8.5 26.9 0.6 8.1 26.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein BORG_CEP PF14957.6 CDJ63418.1 - 0.55 11.4 13.1 1.1 10.5 13.1 1.6 1 0 0 1 1 1 0 Cdc42 effector Otopetrin PF03189.13 CDJ63418.1 - 0.58 8.9 8.3 0.71 8.6 8.3 1.1 1 0 0 1 1 1 0 Otopetrin SAPS PF04499.15 CDJ63418.1 - 0.58 8.9 15.7 0.73 8.5 15.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pox_Ag35 PF03286.14 CDJ63418.1 - 0.88 9.3 14.5 1.3 8.8 14.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Hid1 PF12722.7 CDJ63418.1 - 0.91 7.6 20.8 1.2 7.2 20.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 CDJ63418.1 - 1.1 9.1 22.7 1.6 8.5 22.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Slu7 PF11708.8 CDJ63418.1 - 1.3 8.7 24.6 2.1 8.1 24.6 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Rrn6 PF10214.9 CDJ63418.1 - 1.4 7.3 27.2 1.7 7.0 27.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RP-C_C PF11800.8 CDJ63418.1 - 1.7 8.7 23.9 0.29 11.2 18.3 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region Lin-8 PF03353.15 CDJ63418.1 - 1.8 8.1 26.2 2.8 7.4 26.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cellulose_synt PF03552.14 CDJ63418.1 - 2.2 6.7 7.1 2.7 6.4 7.1 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF4746 PF15928.5 CDJ63418.1 - 2.3 7.6 19.7 3.5 7.0 19.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF778 PF05608.12 CDJ63418.1 - 2.8 8.3 11.7 5 7.5 11.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) BIRC6 PF12356.8 CDJ63418.1 - 2.9 7.3 12.6 5.4 6.4 12.6 1.5 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 Neur_chan_memb PF02932.16 CDJ63418.1 - 3 7.8 19.3 4.3 7.3 19.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Membralin PF09746.9 CDJ63418.1 - 3 6.8 14.1 4 6.4 14.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein eIF-3_zeta PF05091.12 CDJ63418.1 - 3.2 6.6 25.0 4.6 6.1 25.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Endostatin PF06482.11 CDJ63418.1 - 3.3 7.1 19.4 4.6 6.6 19.4 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PAT1 PF09770.9 CDJ63418.1 - 3.8 5.7 38.6 5.2 5.2 38.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3295 PF11702.8 CDJ63418.1 - 3.8 6.8 25.1 5.3 6.3 25.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) ALMT PF11744.8 CDJ63418.1 - 4.1 6.1 20.3 5.3 5.8 20.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Asp-B-Hydro_N PF05279.11 CDJ63418.1 - 5.1 7.1 20.0 7.1 6.6 20.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF913 PF06025.12 CDJ63418.1 - 5.2 5.9 14.0 7.3 5.5 14.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4638 PF15472.6 CDJ63418.1 - 5.3 6.7 16.5 7.8 6.1 16.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) GREB1 PF15782.5 CDJ63418.1 - 5.3 4.0 20.9 6.6 3.7 20.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PPL5 PF18168.1 CDJ63418.1 - 5.5 6.2 14.2 8 5.7 14.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 PPP4R2 PF09184.11 CDJ63418.1 - 5.8 6.4 15.7 7.8 6.0 15.7 1.1 1 0 0 1 1 1 0 PPP4R2 CSRNP_N PF16019.5 CDJ63418.1 - 6.4 6.6 22.1 9 6.1 22.1 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Pal1 PF08316.11 CDJ63418.1 - 6.7 7.5 10.1 13 6.5 10.1 1.5 1 0 0 1 1 1 0 Pal1 cell morphology protein HGTP_anticodon2 PF12745.7 CDJ63418.1 - 6.7 6.1 24.5 12 5.4 24.2 1.4 2 0 0 2 2 1 0 Anticodon binding domain of tRNAs PTPRCAP PF15713.5 CDJ63418.1 - 6.9 6.9 28.0 12 6.2 28.0 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated HCO3_cotransp PF00955.21 CDJ63418.1 - 7.6 5.2 7.5 11 4.7 7.5 1.2 1 0 0 1 1 1 0 HCO3- transporter family Exonuc_VII_L PF02601.15 CDJ63418.1 - 8.3 5.9 25.4 13 5.2 25.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Gti1_Pac2 PF09729.9 CDJ63418.1 - 8.4 6.4 20.1 13 5.9 20.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DAG_kinase_N PF14513.6 CDJ63418.1 - 8.9 6.5 22.5 15 5.8 22.5 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Ureide_permease PF07168.11 CDJ63418.1 - 9.2 4.9 8.4 18 3.9 8.4 1.4 1 0 0 1 1 1 0 Ureide permease Tim54 PF11711.8 CDJ63418.1 - 9.6 4.9 19.2 14 4.3 19.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Band_3_cyto PF07565.13 CDJ63418.1 - 9.7 5.9 19.9 17 5.1 19.9 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CobT PF06213.12 CDJ63418.1 - 9.9 5.5 38.1 17 4.7 38.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SOBP PF15279.6 CDJ63419.1 - 1.4 9.5 15.5 2.1 8.8 15.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_M19 PF01244.21 CDJ63419.1 - 2.7 7.1 6.5 0.084 12.0 0.4 1.5 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) AF-4 PF05110.13 CDJ63420.1 - 3.3 5.7 5.2 4.6 5.2 5.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.12 CDJ63422.1 - 0.0064 16.3 11.3 0.014 15.1 11.3 1.6 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Metallophos PF00149.28 CDJ63425.1 - 4.5e-10 40.4 0.0 5.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Roughex PF06020.11 CDJ63427.1 - 0.00016 20.9 0.4 0.00016 20.9 0.4 3.0 2 1 1 3 3 3 2 Drosophila roughex protein LRR_4 PF12799.7 CDJ63427.1 - 0.02 15.3 3.9 0.23 11.9 0.7 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF1203 PF06718.11 CDJ63427.1 - 0.14 12.5 0.2 0.14 12.5 0.2 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1203) Ferritin-like PF12902.7 CDJ63427.1 - 9.7 6.0 17.2 0.023 14.6 1.6 3.2 2 1 0 3 3 3 0 Ferritin-like zf-Tim10_DDP PF02953.15 CDJ63428.1 - 2.1e-11 43.3 1.9 5.4e-11 42.0 1.9 1.8 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Corona_nucleoca PF00937.18 CDJ63428.1 - 0.031 13.3 2.8 0.036 13.1 2.8 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SR-25 PF10500.9 CDJ63428.1 - 0.052 13.2 11.0 0.072 12.7 11.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4667 PF15700.5 CDJ63428.1 - 0.17 12.0 8.7 0.027 14.6 4.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Peptidase_M24 PF00557.24 CDJ63428.1 - 0.17 11.6 3.6 0.2 11.3 2.9 1.6 1 1 0 1 1 1 0 Metallopeptidase family M24 DUF4667 PF15700.5 CDJ63429.1 - 0.00011 22.4 21.0 0.011 15.8 6.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ63429.1 - 0.00012 22.2 31.3 0.00018 21.7 31.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1645 PF07816.11 CDJ63429.1 - 0.00029 21.5 22.9 0.059 14.0 7.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ63429.1 - 0.00048 19.8 30.9 0.0084 15.7 11.1 2.2 2 0 0 2 2 2 2 Spt20 family DUF755 PF05501.11 CDJ63429.1 - 0.0013 18.9 17.2 0.0013 18.9 17.2 3.2 3 0 0 3 3 2 1 Domain of unknown function (DUF755) Activator_LAG-3 PF11498.8 CDJ63429.1 - 0.0018 17.4 10.4 0.0018 17.4 10.4 2.2 2 0 0 2 2 2 1 Transcriptional activator LAG-3 Lin-8 PF03353.15 CDJ63429.1 - 0.006 16.2 20.8 0.015 14.9 6.2 2.1 2 0 0 2 2 2 2 Ras-mediated vulval-induction antagonist DUF2722 PF10846.8 CDJ63429.1 - 0.0079 15.2 27.7 0.01 14.8 8.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) FliD_N PF02465.18 CDJ63429.1 - 0.015 16.0 5.4 0.015 16.0 5.4 3.1 2 1 0 2 2 1 0 Flagellar hook-associated protein 2 N-terminus DUF5470 PF17564.2 CDJ63429.1 - 0.05 13.8 1.9 0.05 13.8 1.9 2.4 2 0 0 2 2 1 0 Family of unknown function (DUF5470) BORG_CEP PF14957.6 CDJ63429.1 - 0.065 14.4 18.2 0.92 10.7 6.3 2.2 2 0 0 2 2 2 0 Cdc42 effector Pap_E4 PF02711.14 CDJ63429.1 - 0.37 11.8 19.8 0.074 14.0 2.1 3.4 3 0 0 3 3 3 0 E4 protein Eapp_C PF10238.9 CDJ63429.1 - 4.7 7.3 11.3 4.9 7.2 1.5 2.5 3 0 0 3 3 3 0 E2F-associated phosphoprotein CagX PF03524.15 CDJ63429.1 - 4.8 6.8 9.3 5.4 6.7 0.7 2.2 2 0 0 2 2 2 0 Conjugal transfer protein AP-5_subunit_s1 PF15001.6 CDJ63429.1 - 8.7 6.3 14.5 0.61 10.1 4.4 2.2 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 IMUP PF15761.5 CDJ63429.1 - 9 7.0 30.4 0.82 10.4 6.5 2.9 3 0 0 3 3 3 0 Immortalisation up-regulated protein JUPITER PF17054.5 CDJ63429.1 - 9.6 5.6 13.3 8.5 5.7 2.4 2.2 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter LIAS_N PF16881.5 CDJ63430.1 - 0.058 13.8 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family Ribosomal_60s PF00428.19 CDJ63430.1 - 1.7 9.3 45.6 1.8 9.2 9.1 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein ASFV_J13L PF05568.11 CDJ63431.1 - 0.011 15.5 6.5 0.011 15.5 5.2 1.7 1 1 1 2 2 2 0 African swine fever virus J13L protein RAP1 PF07218.11 CDJ63431.1 - 0.34 9.1 7.6 0.37 9.0 7.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 CDJ63431.1 - 0.35 9.7 7.8 0.47 9.3 7.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ63431.1 - 1.4 7.4 9.9 1.9 7.0 9.9 1.2 1 0 0 1 1 1 0 Macoilin family CBF PF03914.17 CDJ63433.1 - 1.8e-25 89.9 0.1 1.8e-25 89.9 0.1 4.4 4 1 0 5 5 5 1 CBF/Mak21 family SLC12 PF03522.15 CDJ63434.1 - 0.014 14.4 26.2 0.016 14.3 26.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 GAGA_bind PF06217.12 CDJ63434.1 - 0.29 11.4 22.1 0.4 10.9 22.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.7 CDJ63434.1 - 1.9 6.5 37.3 2.3 6.2 37.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.6 CDJ63434.1 - 2.5 7.6 34.8 3.3 7.3 34.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Zip PF02535.22 CDJ63434.1 - 3.1 6.9 16.4 5.1 6.2 16.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Caldesmon PF02029.15 CDJ63434.1 - 4.2 6.0 46.8 5.2 5.7 46.8 1.1 1 0 0 1 1 1 0 Caldesmon V_ATPase_I PF01496.19 CDJ63434.1 - 4.9 4.9 30.7 6.7 4.5 30.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dapper PF15268.6 CDJ63434.1 - 5.9 5.6 39.2 7.1 5.4 39.2 1.0 1 0 0 1 1 1 0 Dapper DUF674 PF05056.12 CDJ63434.1 - 6.8 5.4 13.6 9 5.0 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) SLAM PF06214.11 CDJ63435.1 - 0.058 13.4 0.0 13 5.9 0.0 2.3 1 1 1 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein PAT1 PF09770.9 CDJ63435.1 - 0.44 8.8 10.5 0.5 8.6 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MMR1 PF08505.10 CDJ63435.1 - 0.96 9.7 6.5 1.7 8.9 6.5 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RR_TM4-6 PF06459.12 CDJ63435.1 - 2.9 7.7 9.3 4.2 7.1 9.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ63435.1 - 4.6 5.9 6.8 6.4 5.4 6.8 1.3 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ63435.1 - 6.7 6.3 12.7 12 5.4 12.7 1.4 1 0 0 1 1 1 0 Spt20 family NST1 PF13945.6 CDJ63435.1 - 6.8 6.7 11.4 16 5.5 11.4 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator Ribosomal_S30 PF04758.14 CDJ63437.1 - 1.5e-25 89.2 4.7 2e-25 88.7 4.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 GYF_2 PF14237.6 CDJ63437.1 - 0.11 12.3 0.5 5.2 7.0 0.0 2.8 2 1 1 3 3 3 0 GYF domain 2 Fib_alpha PF08702.10 CDJ63439.1 - 0.053 13.7 0.5 0.053 13.7 0.5 2.4 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Gp-FAR-1 PF05823.12 CDJ63439.1 - 0.092 13.1 1.0 0.19 12.1 1.0 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Prefoldin PF02996.17 CDJ63439.1 - 0.28 11.1 6.1 0.55 10.2 4.8 2.2 1 1 1 2 2 2 0 Prefoldin subunit MIT PF04212.18 CDJ63439.1 - 0.4 10.8 6.6 4 7.6 0.7 2.7 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain NTP_transferase PF00483.23 CDJ63439.1 - 0.42 10.2 2.7 0.69 9.5 1.6 1.9 1 1 0 1 1 1 0 Nucleotidyl transferase PIN_8 PF18476.1 CDJ63439.1 - 0.77 9.6 10.3 0.11 12.4 1.0 2.5 3 0 0 3 3 3 0 PIN like domain CorA PF01544.18 CDJ63439.1 - 1.3 8.3 6.2 0.62 9.3 2.9 2.0 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein YscO-like PF16789.5 CDJ63439.1 - 1.6 8.7 8.2 1.3 9.1 6.3 1.8 1 1 0 1 1 1 0 YscO-like protein GrpE PF01025.19 CDJ63439.1 - 1.8 8.2 11.0 7.4 6.2 11.1 2.1 1 1 0 1 1 1 0 GrpE DUF883 PF05957.13 CDJ63439.1 - 2.2 8.9 14.0 0.41 11.3 5.7 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) SPX PF03105.19 CDJ63439.1 - 2.8 7.8 27.1 3 7.7 17.6 2.5 2 0 0 2 2 2 0 SPX domain CLZ PF16526.5 CDJ63439.1 - 6.8 7.1 9.6 35 4.9 0.2 3.2 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BST2 PF16716.5 CDJ63439.1 - 9.4 6.9 14.0 0.34 11.5 3.5 3.3 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 ThiF PF00899.21 CDJ63440.1 - 9.4e-57 192.2 0.0 1.5e-31 109.6 0.0 4.7 4 1 0 4 4 4 4 ThiF family 2-Hacid_dh_C PF02826.19 CDJ63440.1 - 9.3e-05 21.9 0.0 0.046 13.1 0.0 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CDJ63440.1 - 0.00012 22.1 0.2 0.28 11.2 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 CDJ63440.1 - 0.00033 20.0 0.1 0.17 11.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ63440.1 - 0.0065 17.0 1.4 2.2 8.9 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_thiolCys PF10585.9 CDJ63440.1 - 0.016 15.1 0.0 7.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 CDJ63440.1 - 0.017 15.6 0.3 0.78 10.2 0.0 3.0 3 0 0 3 3 3 0 Putative NAD(P)-binding E1_UFD PF09358.10 CDJ63440.1 - 0.036 14.8 0.0 0.15 12.7 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin fold domain ANAPC4_WD40 PF12894.7 CDJ63441.1 - 0.0014 18.9 0.0 1.2 9.5 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain rve PF00665.26 CDJ63443.1 - 0.00035 20.7 0.1 0.00095 19.3 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Ras PF00071.22 CDJ63444.1 - 2.5e-59 199.5 0.0 3.2e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ63444.1 - 1.7e-33 115.3 0.0 2.4e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ63444.1 - 8.8e-13 48.1 0.0 1.1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ63444.1 - 3.6e-06 26.5 0.0 4.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ63444.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ63444.1 - 0.011 15.2 0.1 0.037 13.6 0.0 1.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CDJ63444.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDJ63444.1 - 0.029 14.3 0.0 3.4 7.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CDJ63444.1 - 0.092 13.1 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CDJ63444.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein MORN PF02493.20 CDJ63445.1 - 1.7e-49 162.8 52.8 2.4e-06 27.1 3.0 10.2 10 0 0 10 10 10 10 MORN repeat DUF3048_C PF17479.2 CDJ63445.1 - 3.6 8.0 9.0 21 5.5 0.4 3.8 1 1 2 4 4 4 0 Protein of unknown function (DUF3048) C-terminal domain Pkinase PF00069.25 CDJ63446.1 - 5.9e-35 120.9 0.0 2.6e-26 92.6 0.0 4.3 4 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63446.1 - 3.8e-34 118.1 1.3 4.5e-14 52.3 0.0 5.1 4 2 0 4 4 4 3 Protein tyrosine kinase AAA PF00004.29 CDJ63447.1 - 7.2e-17 62.0 0.0 1.3e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CDJ63447.1 - 6.4e-12 45.6 0.1 7.6e-10 38.8 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CDJ63447.1 - 9.5e-12 45.2 0.0 2.3e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 CDJ63447.1 - 1.3e-06 28.8 0.1 2e-05 24.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ63447.1 - 2.8e-06 27.8 0.1 0.00025 21.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CDJ63447.1 - 4.1e-06 26.7 0.0 8.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ63447.1 - 1.2e-05 25.1 0.0 5.9e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 CDJ63447.1 - 1.5e-05 24.9 0.1 4.2e-05 23.5 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 CDJ63447.1 - 1.9e-05 24.7 0.0 3.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CDJ63447.1 - 5.7e-05 23.4 0.0 0.00015 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain ResIII PF04851.15 CDJ63447.1 - 0.00062 19.8 0.0 0.0086 16.1 0.0 2.1 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 CDJ63447.1 - 0.002 18.1 0.1 0.011 15.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CDJ63447.1 - 0.0021 18.0 0.0 0.0044 16.9 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_19 PF13245.6 CDJ63447.1 - 0.0029 17.9 0.1 0.012 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDJ63447.1 - 0.0042 16.4 0.0 0.011 15.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CDJ63447.1 - 0.009 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region DEAD PF00270.29 CDJ63447.1 - 0.0099 15.7 0.1 0.19 11.5 0.0 2.2 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_24 PF13479.6 CDJ63447.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CDJ63447.1 - 0.028 13.8 0.1 0.19 11.1 0.1 2.0 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ63447.1 - 0.037 13.9 0.1 0.56 10.1 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CDJ63447.1 - 0.08 12.3 0.0 4.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 CDJ63447.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 CDJ63447.1 - 0.092 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CDJ63447.1 - 0.099 12.1 0.0 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Syntaxin-6_N PF09177.11 CDJ63449.1 - 0.003 18.1 7.0 0.003 18.1 7.0 2.1 1 1 0 2 2 2 1 Syntaxin 6, N-terminal DUF1664 PF07889.12 CDJ63449.1 - 0.0039 17.2 11.7 0.011 15.7 5.8 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) HMMR_N PF15905.5 CDJ63449.1 - 0.0074 15.8 19.8 0.01 15.3 19.8 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Mer2 PF09074.10 CDJ63449.1 - 0.0087 15.9 9.4 0.012 15.4 9.4 1.3 1 0 0 1 1 1 1 Mer2 Filament PF00038.21 CDJ63449.1 - 0.026 14.1 21.8 0.18 11.3 10.3 2.2 1 1 1 2 2 2 0 Intermediate filament protein Lipoprotein_6 PF01441.19 CDJ63449.1 - 0.029 14.4 4.8 0.034 14.2 3.7 1.6 1 1 0 1 1 1 0 Lipoprotein DUF4706 PF15797.5 CDJ63449.1 - 0.034 14.7 3.1 0.061 13.9 2.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4706) Gp58 PF07902.11 CDJ63449.1 - 0.051 11.9 4.1 0.064 11.5 4.1 1.2 1 0 0 1 1 1 0 gp58-like protein ApoLp-III PF07464.11 CDJ63449.1 - 0.061 13.4 12.3 0.81 9.8 11.5 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Cob_adeno_trans PF01923.18 CDJ63449.1 - 0.068 13.3 5.1 0.044 13.9 3.0 1.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase EST1 PF10374.9 CDJ63449.1 - 0.074 13.7 6.7 0.1 13.2 6.7 1.5 1 1 0 1 1 1 0 Telomerase activating protein Est1 CHDCT2 PF08074.11 CDJ63449.1 - 0.089 13.0 10.1 2.2 8.4 10.1 2.1 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain DUF948 PF06103.11 CDJ63449.1 - 0.11 12.8 4.5 5.1 7.4 0.3 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 CDJ63449.1 - 0.11 13.1 8.3 0.62 10.7 1.4 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) NBD_C PF17042.5 CDJ63449.1 - 0.13 12.8 4.0 0.19 12.2 4.0 1.3 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain Tropomyosin_1 PF12718.7 CDJ63449.1 - 0.33 11.1 27.6 0.51 10.5 14.3 2.6 1 1 1 2 2 2 0 Tropomyosin like Baculo_PEP_C PF04513.12 CDJ63449.1 - 0.34 11.0 9.5 2.8 8.0 2.6 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.8 CDJ63449.1 - 0.38 11.0 24.9 1.8 8.8 7.7 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding FAM184 PF15665.5 CDJ63449.1 - 0.48 10.2 19.6 0.62 9.8 19.6 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Golgin_A5 PF09787.9 CDJ63449.1 - 0.61 9.5 21.6 0.78 9.2 21.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 OmpH PF03938.14 CDJ63449.1 - 0.69 10.2 25.8 0.049 14.0 14.8 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Spectrin PF00435.21 CDJ63449.1 - 0.76 10.3 16.2 3.8 8.1 8.7 2.5 1 1 1 2 2 2 0 Spectrin repeat Spc7 PF08317.11 CDJ63449.1 - 1.1 8.0 19.4 2.8 6.8 19.3 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 CDJ63449.1 - 1.3 8.3 14.6 2.8 7.2 14.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 CDJ63449.1 - 1.4 8.4 13.2 1.7 8.1 13.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bcr-Abl_Oligo PF09036.10 CDJ63449.1 - 1.4 9.0 5.6 3 7.9 0.4 2.8 1 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Tweety PF04906.13 CDJ63449.1 - 1.5 7.4 6.3 2.4 6.8 2.2 2.0 1 1 1 2 2 2 0 Tweety Atg14 PF10186.9 CDJ63449.1 - 1.8 7.6 12.5 2.9 6.9 12.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 CDJ63449.1 - 2 7.6 12.3 0.85 8.8 6.2 2.0 1 1 2 3 3 3 0 TMPIT-like protein ISG65-75 PF11727.8 CDJ63449.1 - 2.2 7.5 9.1 0.88 8.8 6.0 1.8 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF724 PF05266.14 CDJ63449.1 - 2.6 7.8 14.4 0.39 10.5 6.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) 7TMR-HDED PF07697.11 CDJ63449.1 - 4.6 7.3 19.9 13 5.9 19.9 1.6 1 1 0 1 1 1 0 7TM-HD extracellular TPR_MLP1_2 PF07926.12 CDJ63449.1 - 4.9 7.2 27.2 1.9 8.6 19.3 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein YlqD PF11068.8 CDJ63449.1 - 5.2 7.4 21.4 0.31 11.4 4.6 2.6 1 1 1 2 2 2 0 YlqD protein V_ATPase_I PF01496.19 CDJ63449.1 - 6.7 4.5 10.3 10 3.9 8.7 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 CDJ63449.1 - 8.2 4.8 7.8 9.8 4.6 7.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 CDJ63449.1 - 9.9 6.9 17.7 16 6.2 7.5 2.8 1 1 1 2 2 2 0 Initiation control protein YabA Cation_efflux PF01545.21 CDJ63450.1 - 1.7e-45 155.2 5.8 2.2e-45 154.9 5.8 1.1 1 0 0 1 1 1 1 Cation efflux family Virul_fac_BrkB PF03631.15 CDJ63451.1 - 0.044 13.4 0.1 0.23 11.0 0.1 1.9 2 0 0 2 2 2 0 Virulence factor BrkB DNA_pol_A_exo1 PF01612.20 CDJ63452.1 - 6.9e-35 120.3 0.0 1.3e-34 119.4 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 CDJ63452.1 - 7.7e-10 38.6 0.1 1.8e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 CDJ63452.1 - 0.044 14.5 0.8 1.1 10.0 0.4 3.1 2 1 0 2 2 2 0 PMC2NT (NUC016) domain RNase_T PF00929.24 CDJ63453.1 - 2.5e-28 99.7 0.0 2.8e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 CDJ63453.1 - 0.00057 19.9 0.0 0.00071 19.6 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like eIF2A PF08662.11 CDJ63454.1 - 1.1e-38 133.1 0.0 3.4e-31 108.6 0.0 3.5 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A GYF PF02213.16 CDJ63454.1 - 3.7e-16 58.5 0.0 9.2e-16 57.2 0.0 1.8 1 0 0 1 1 1 1 GYF domain ANAPC4_WD40 PF12894.7 CDJ63454.1 - 0.0028 17.9 1.8 3.2 8.1 0.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Chromo PF00385.24 CDJ63455.1 - 9.7e-14 51.0 0.0 2e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SUIM_assoc PF16619.5 CDJ63456.1 - 0.54 10.4 25.7 0.48 10.5 9.5 3.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Cyclin PF08613.11 CDJ63458.1 - 2.3e-31 109.4 0.1 2.3e-31 109.4 0.1 6.5 7 2 0 7 7 7 1 Cyclin Cyclin_N PF00134.23 CDJ63458.1 - 2.3e-07 30.6 0.0 2.3e-07 30.6 0.0 5.1 6 2 1 7 7 7 1 Cyclin, N-terminal domain SR-25 PF10500.9 CDJ63460.1 - 4.9e-05 23.1 25.7 5.6e-05 22.9 25.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ63460.1 - 0.011 16.1 24.1 0.016 15.6 24.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Roughex PF06020.11 CDJ63460.1 - 0.016 14.3 10.5 0.016 14.4 10.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ63460.1 - 0.022 14.4 30.5 0.024 14.2 30.5 1.1 1 0 0 1 1 1 0 Spt20 family Lin-8 PF03353.15 CDJ63460.1 - 0.048 13.2 16.0 0.048 13.2 16.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NEMP PF10225.9 CDJ63460.1 - 0.048 13.3 5.7 0.053 13.2 5.7 1.0 1 0 0 1 1 1 0 NEMP family SARAF PF06682.12 CDJ63460.1 - 0.062 12.9 11.0 0.087 12.5 11.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4820 PF16091.5 CDJ63460.1 - 0.11 11.8 7.3 0.11 11.8 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DDHD PF02862.17 CDJ63460.1 - 0.23 11.6 11.0 0.23 11.6 11.0 1.1 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.13 CDJ63460.1 - 0.27 10.2 14.1 0.32 9.9 14.1 1.0 1 0 0 1 1 1 0 Paf1 TFIIA PF03153.13 CDJ63460.1 - 0.28 11.1 34.4 0.3 11.0 34.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 CDJ63460.1 - 0.3 9.5 2.8 0.27 9.6 2.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TERB2 PF15101.6 CDJ63460.1 - 0.33 11.0 15.8 0.39 10.7 15.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Band_3_cyto PF07565.13 CDJ63460.1 - 0.34 10.7 10.9 0.35 10.6 10.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain OATP PF03137.20 CDJ63460.1 - 0.36 9.1 4.6 0.43 8.8 4.6 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Apt1 PF10351.9 CDJ63460.1 - 0.36 9.6 15.2 0.34 9.7 15.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain FHIPEP PF00771.20 CDJ63460.1 - 0.39 9.1 4.8 0.45 8.9 4.8 1.0 1 0 0 1 1 1 0 FHIPEP family DUF755 PF05501.11 CDJ63460.1 - 0.39 11.0 33.5 0.61 10.4 33.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) BAF1_ABF1 PF04684.13 CDJ63460.1 - 0.49 9.4 12.4 0.57 9.2 12.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3408 PF11888.8 CDJ63460.1 - 0.53 10.4 8.6 0.64 10.2 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SPX PF03105.19 CDJ63460.1 - 0.54 10.1 17.2 0.52 10.2 17.2 1.0 1 0 0 1 1 1 0 SPX domain DUF1980 PF09323.10 CDJ63460.1 - 0.55 10.1 5.9 0.58 10.0 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4179 PF13786.6 CDJ63460.1 - 0.59 10.6 3.7 0.82 10.2 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) GREB1 PF15782.5 CDJ63460.1 - 0.74 6.9 20.9 0.76 6.8 20.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SpoIIP PF07454.11 CDJ63460.1 - 0.74 9.2 9.9 0.82 9.1 9.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Mem_trans PF03547.18 CDJ63460.1 - 0.85 7.9 5.9 0.86 7.9 5.9 1.2 1 0 0 1 1 1 0 Membrane transport protein UPF0560 PF10577.9 CDJ63460.1 - 0.96 7.9 16.4 1.1 7.7 16.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Tim54 PF11711.8 CDJ63460.1 - 0.96 8.2 7.6 0.84 8.4 7.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 CDJ63460.1 - 1 9.4 6.6 0.91 9.5 6.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF572 PF04502.13 CDJ63460.1 - 1.2 8.7 13.9 1.3 8.6 13.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) ATP11 PF06644.11 CDJ63460.1 - 1.2 8.8 12.9 1.4 8.7 12.9 1.2 1 0 0 1 1 1 0 ATP11 protein IHABP4_N PF16174.5 CDJ63460.1 - 1.4 9.5 15.1 2 9.0 15.1 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Presenilin PF01080.17 CDJ63460.1 - 1.4 7.6 16.2 1.4 7.6 16.2 1.0 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 CDJ63460.1 - 1.5 9.2 7.8 1.7 9.0 7.8 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2722 PF10846.8 CDJ63460.1 - 1.5 7.7 29.8 2.2 7.1 29.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ63460.1 - 2.5 8.0 13.7 2.7 7.9 13.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EIIBC-GUT_N PF03612.14 CDJ63460.1 - 2.9 7.6 6.9 2.9 7.6 6.9 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CCDC106 PF15794.5 CDJ63460.1 - 3.1 7.5 20.8 3.8 7.2 20.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Smg8_Smg9 PF10220.9 CDJ63460.1 - 3.3 5.9 14.2 3.3 5.9 14.2 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Conotoxin PF02950.17 CDJ63460.1 - 3.6 8.7 6.6 7.9 7.6 6.6 1.6 1 0 0 1 1 1 0 Conotoxin DUF4834 PF16118.5 CDJ63460.1 - 4.8 8.2 15.4 6.1 7.9 15.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ63460.1 - 5 6.8 8.1 6.1 6.5 8.1 1.1 1 0 0 1 1 1 0 FAM176 family PAP1 PF08601.10 CDJ63460.1 - 5.5 6.6 26.3 6.6 6.3 26.3 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 API5 PF05918.11 CDJ63460.1 - 5.6 5.7 12.5 6 5.6 12.5 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ctr PF04145.15 CDJ63460.1 - 5.9 7.5 6.6 6.4 7.4 6.6 1.3 1 0 0 1 1 1 0 Ctr copper transporter family DUF4770 PF15994.5 CDJ63460.1 - 6.4 7.0 12.0 8.4 6.6 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Miga PF10265.9 CDJ63460.1 - 6.6 5.6 12.3 6.7 5.6 12.3 1.1 1 0 0 1 1 1 0 Mitoguardin CLN3 PF02487.17 CDJ63460.1 - 8.2 5.4 9.2 8.7 5.3 9.2 1.1 1 0 0 1 1 1 0 CLN3 protein EPL1 PF10513.9 CDJ63460.1 - 9.7 6.6 15.1 11 6.4 15.1 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Ndc1_Nup PF09531.10 CDJ63460.1 - 10 4.7 18.2 9.4 4.8 18.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RIB43A PF05914.12 CDJ63461.1 - 1.3e-06 27.4 16.3 1.3e-06 27.4 16.3 7.4 7 1 0 7 7 7 1 RIB43A FAM101 PF15068.6 CDJ63461.1 - 0.3 11.0 12.2 0.039 13.9 4.4 3.4 2 0 0 2 2 2 0 FAM101 family Bac_DNA_binding PF00216.21 CDJ63462.1 - 0.0097 16.1 0.7 0.022 15.0 0.3 1.9 1 1 1 2 2 2 1 Bacterial DNA-binding protein TFIIA PF03153.13 CDJ63462.1 - 0.017 15.2 35.1 0.021 14.8 35.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HTH_IclR PF09339.10 CDJ63462.1 - 0.023 14.5 0.2 0.023 14.5 0.2 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HU-HIG PF18291.1 CDJ63462.1 - 0.066 13.3 3.5 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif T-box_assoc PF16176.5 CDJ63462.1 - 0.11 12.5 7.2 0.026 14.6 2.9 1.8 1 1 1 2 2 2 0 T-box transcription factor-associated Med15 PF09606.10 CDJ63462.1 - 0.15 10.8 27.8 0.19 10.4 27.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 CDJ63462.1 - 0.4 9.4 10.3 0.54 9.0 10.3 1.2 1 0 0 1 1 1 0 Presenilin RIFIN PF02009.16 CDJ63462.1 - 0.53 10.1 8.5 0.68 9.8 8.5 1.1 1 0 0 1 1 1 0 Rifin eIF3_p135 PF12807.7 CDJ63462.1 - 1.7 8.7 10.1 1.4 8.9 3.9 2.0 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit 135 GREB1 PF15782.5 CDJ63462.1 - 2.4 5.2 13.9 2.9 4.9 13.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAPS PF04499.15 CDJ63463.1 - 0.072 11.9 17.6 0.071 11.9 17.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AMP-binding PF00501.28 CDJ63463.1 - 0.24 10.0 4.6 0.29 9.7 4.6 1.1 1 0 0 1 1 1 0 AMP-binding enzyme ALMT PF11744.8 CDJ63463.1 - 0.26 10.1 22.0 0.26 10.1 22.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RIFIN PF02009.16 CDJ63463.1 - 0.42 10.4 17.2 0.63 9.9 17.2 1.3 1 0 0 1 1 1 0 Rifin Ribosomal_60s PF00428.19 CDJ63463.1 - 0.43 11.2 4.4 1.1 9.9 4.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein FapA PF03961.13 CDJ63463.1 - 0.6 8.7 12.8 0.65 8.5 12.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_11 PF13086.6 CDJ63463.1 - 0.96 9.2 29.0 1.3 8.8 29.0 1.2 1 0 0 1 1 1 0 AAA domain CAC1F_C PF16885.5 CDJ63463.1 - 1.4 8.5 21.5 1.5 8.4 21.5 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Endostatin PF06482.11 CDJ63463.1 - 1.9 7.9 30.8 2.7 7.4 30.8 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SLC12 PF03522.15 CDJ63463.1 - 3.1 6.7 32.9 4.3 6.3 32.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PAT1 PF09770.9 CDJ63463.1 - 4.8 5.3 53.0 5.8 5.0 53.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 VIR_N PF15912.5 CDJ63463.1 - 6.7 6.2 21.9 9.7 5.7 21.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Nop53 PF07767.11 CDJ63463.1 - 7.3 5.9 40.9 8.6 5.6 40.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2981 PF11200.8 CDJ63463.1 - 8.8 6.0 9.5 9.6 5.8 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) RskA PF10099.9 CDJ63466.1 - 6.5e-05 23.3 15.2 8.2e-05 23.0 15.2 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Med3 PF11593.8 CDJ63466.1 - 0.0059 15.9 4.8 0.0059 15.9 4.8 2.0 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal TFIIA PF03153.13 CDJ63466.1 - 0.011 15.8 6.5 0.013 15.5 6.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ63466.1 - 0.02 14.5 9.8 0.027 14.1 9.8 1.2 1 0 0 1 1 1 0 Spt20 family AFT PF08731.11 CDJ63466.1 - 0.02 15.3 0.7 0.03 14.7 0.7 1.2 1 0 0 1 1 1 0 Transcription factor AFT CDK2AP PF09806.9 CDJ63466.1 - 0.054 13.5 1.1 0.054 13.5 1.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein FRG1 PF06229.12 CDJ63466.1 - 0.084 12.6 2.3 0.12 12.1 2.3 1.2 1 0 0 1 1 1 0 FRG1-like domain DUF2722 PF10846.8 CDJ63466.1 - 0.13 11.2 7.2 0.17 10.8 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ63466.1 - 0.15 13.0 1.1 0.24 12.4 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FYDLN_acid PF09538.10 CDJ63466.1 - 0.25 12.0 0.3 0.25 12.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SUIM_assoc PF16619.5 CDJ63466.1 - 0.38 10.8 19.5 7 6.8 19.5 2.5 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TraU PF06834.11 CDJ63466.1 - 1.2 8.4 6.9 2.8 7.1 6.9 1.5 1 1 0 1 1 1 0 TraU protein Sec62 PF03839.16 CDJ63466.1 - 2.2 7.8 4.1 2.6 7.5 4.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Adeno_PV PF03910.13 CDJ63466.1 - 7.4 5.2 10.9 12 4.5 10.9 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV T6SS_TssG PF06996.11 CDJ63467.1 - 0.072 12.3 1.8 0.095 11.9 1.8 1.1 1 0 0 1 1 1 0 Type VI secretion, TssG Helo_like_N PF17111.5 CDJ63467.1 - 0.098 12.0 0.5 0.14 11.5 0.5 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins TBCC_N PF16752.5 CDJ63467.1 - 0.13 12.7 0.4 0.19 12.2 0.4 1.2 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain THOC7 PF05615.13 CDJ63467.1 - 0.28 11.4 1.9 0.39 11.0 1.9 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 S1-P1_nuclease PF02265.16 CDJ63470.1 - 2.6e-25 89.7 1.4 2.6e-25 89.7 1.4 2.4 1 1 1 2 2 1 1 S1/P1 Nuclease SOBP PF15279.6 CDJ63470.1 - 0.0018 19.0 38.3 0.025 15.2 7.9 2.2 2 0 0 2 2 2 2 Sine oculis-binding protein TFIIA PF03153.13 CDJ63470.1 - 0.0021 18.1 44.8 0.0021 18.1 44.8 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ63470.1 - 0.016 15.0 0.2 0.016 15.0 0.2 2.9 3 0 0 3 3 3 0 Connexin DUF3391 PF11871.8 CDJ63470.1 - 0.021 15.4 2.2 0.021 15.4 2.2 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF3391) Serinc PF03348.15 CDJ63470.1 - 0.048 12.6 11.2 0.057 12.3 0.1 2.4 2 0 0 2 2 2 0 Serine incorporator (Serinc) SPX PF03105.19 CDJ63470.1 - 0.28 11.1 23.3 0.035 14.0 2.4 2.4 2 0 0 2 2 2 0 SPX domain Apt1 PF10351.9 CDJ63470.1 - 0.67 8.7 22.1 0.46 9.3 2.0 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Lin-8 PF03353.15 CDJ63470.1 - 2 7.9 49.9 2.7 7.5 26.9 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 CDJ63470.1 - 2.6 7.0 41.2 4.4 6.2 7.7 2.4 2 1 0 2 2 2 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ63470.1 - 3.6 5.9 11.1 4.5 5.6 0.1 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Exonuc_VII_L PF02601.15 CDJ63470.1 - 5.6 6.4 28.9 2.1 7.8 15.4 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit SR-25 PF10500.9 CDJ63470.1 - 7.6 6.1 43.6 0.017 14.8 8.0 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF4173 PF13777.6 CDJ63471.1 - 2.9 7.3 12.9 6.6 6.1 12.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Aminotran_5 PF00266.19 CDJ63473.1 - 3.6e-06 26.2 0.1 5e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Med3 PF11593.8 CDJ63473.1 - 0.0042 16.3 8.8 0.0056 15.9 8.8 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal OmpH PF03938.14 CDJ63473.1 - 0.01 16.2 10.3 0.016 15.5 10.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TFIIA PF03153.13 CDJ63473.1 - 0.014 15.4 9.8 0.017 15.2 9.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.8 CDJ63473.1 - 0.042 13.0 7.4 0.052 12.7 7.4 1.1 1 0 0 1 1 1 0 SprA-related family Neur_chan_memb PF02932.16 CDJ63473.1 - 0.054 13.5 0.9 0.067 13.2 0.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 CDJ63473.1 - 0.071 12.7 13.6 0.093 12.3 13.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF5106 PF17127.4 CDJ63473.1 - 0.34 11.2 5.3 1.7 8.9 5.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5106) DUF2722 PF10846.8 CDJ63473.1 - 4.4 6.1 15.4 5.6 5.8 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4366 PF14283.6 CDJ63474.1 - 0.012 15.6 0.5 0.018 15.1 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 CDJ63474.1 - 0.03 13.1 0.6 0.03 13.1 0.6 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ63474.1 - 0.081 12.9 16.3 0.11 12.4 16.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EIIBC-GUT_N PF03612.14 CDJ63474.1 - 0.2 11.4 0.8 0.37 10.5 0.8 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ctr PF04145.15 CDJ63474.1 - 0.43 11.2 1.7 0.67 10.6 1.7 1.2 1 0 0 1 1 1 0 Ctr copper transporter family GHMP_kinases_N PF00288.26 CDJ63475.1 - 5.2e-05 23.4 0.0 5.2e-05 23.4 0.0 11.0 8 4 4 12 12 12 1 GHMP kinases N terminal domain RskA PF10099.9 CDJ63475.1 - 6e-05 23.4 8.7 6e-05 23.4 8.7 7.2 2 2 3 5 5 5 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ63475.1 - 0.00041 19.4 15.3 0.00041 19.4 15.3 4.3 5 0 0 5 5 5 2 Protein of unknown function (DUF2722) SID-1_RNA_chan PF13965.6 CDJ63475.1 - 0.13 10.7 2.8 0.28 9.6 2.8 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PCEMA1 PF07418.11 CDJ63475.1 - 0.21 11.1 1.6 0.31 10.5 1.6 1.3 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 FAM91_C PF14648.6 CDJ63475.1 - 0.23 10.3 10.0 0.4 9.5 10.0 1.4 1 0 0 1 1 1 0 FAM91 C-terminus Activator_LAG-3 PF11498.8 CDJ63475.1 - 0.27 10.2 75.4 0.59 9.0 1.0 3.6 3 0 0 3 3 3 0 Transcriptional activator LAG-3 Tim54 PF11711.8 CDJ63475.1 - 1.8 7.3 7.7 5.4 5.7 7.7 1.8 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 CDJ63475.1 - 1.8 7.5 14.2 1.6 7.7 9.0 2.5 2 0 0 2 2 2 0 Solute carrier family 12 EphA2_TM PF14575.6 CDJ63475.1 - 4.7 8.2 16.2 4 8.4 2.1 4.7 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain SAPS PF04499.15 CDJ63476.1 - 0.15 10.9 0.7 0.19 10.5 0.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 CDJ63476.1 - 0.28 10.0 13.8 0.46 9.3 13.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2339 PF10101.9 CDJ63476.1 - 2 6.9 28.1 2.9 6.4 28.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF4834 PF16118.5 CDJ63477.1 - 0.0046 17.9 8.8 0.0046 17.9 8.8 2.5 2 1 0 2 2 1 1 Domain of unknown function (DUF4834) Rxt3 PF08642.10 CDJ63477.1 - 0.014 16.2 6.5 0.12 13.1 1.5 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF755 PF05501.11 CDJ63477.1 - 0.014 15.6 7.9 0.014 15.6 7.9 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF755) Orf78 PF06024.12 CDJ63477.1 - 0.016 15.5 1.1 0.016 15.5 1.1 2.5 2 1 1 3 3 2 0 Orf78 (ac78) DUF1764 PF08576.10 CDJ63477.1 - 0.06 14.3 8.7 0.051 14.5 2.5 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Usp PF00582.26 CDJ63477.1 - 0.067 13.7 14.4 1 9.9 0.1 2.2 2 0 0 2 2 2 0 Universal stress protein family TRA-1_regulated PF02343.16 CDJ63477.1 - 0.078 13.0 2.4 0.4 10.7 0.1 2.2 2 0 0 2 2 2 0 TRA-1 regulated protein R03H10.4 Peptidase_S49_N PF08496.10 CDJ63477.1 - 0.15 12.2 12.7 0.13 12.3 5.8 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SpoIIP PF07454.11 CDJ63477.1 - 0.21 11.0 15.4 0.43 10.0 10.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) G0-G1_switch_2 PF15103.6 CDJ63477.1 - 0.22 12.0 15.0 2.7 8.5 0.7 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 Trp_oprn_chp PF09534.10 CDJ63477.1 - 0.35 10.7 38.4 1.2 8.9 23.1 2.5 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TERB2 PF15101.6 CDJ63477.1 - 0.36 10.9 23.2 0.09 12.8 12.1 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 BORG_CEP PF14957.6 CDJ63477.1 - 0.82 10.8 15.1 3.8 8.7 2.5 2.1 2 0 0 2 2 2 0 Cdc42 effector SR-25 PF10500.9 CDJ63477.1 - 1.3 8.6 24.5 1.6 8.3 9.3 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Band_3_cyto PF07565.13 CDJ63477.1 - 1.3 8.8 19.1 3.4 7.4 1.9 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2232 PF09991.9 CDJ63477.1 - 1.3 8.1 6.5 0.15 11.2 2.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Peptidase_U57 PF05582.12 CDJ63477.1 - 1.5 8.1 11.0 0.33 10.2 5.0 2.0 2 0 0 2 2 2 0 YabG peptidase U57 DUF2207 PF09972.9 CDJ63477.1 - 1.6 7.4 3.2 0.59 8.8 0.1 1.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Folate_carrier PF01770.18 CDJ63477.1 - 1.7 7.3 6.8 0.35 9.6 1.9 2.0 2 0 0 2 2 2 0 Reduced folate carrier SID-1_RNA_chan PF13965.6 CDJ63477.1 - 2.1 6.7 9.5 3.6 5.9 9.5 1.5 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 FAM176 PF14851.6 CDJ63477.1 - 2.6 7.7 8.1 0.99 9.1 3.7 2.1 2 0 0 2 2 2 0 FAM176 family Coilin_N PF15862.5 CDJ63477.1 - 2.7 7.8 23.2 6.3 6.6 0.4 2.3 2 0 0 2 2 2 0 Coilin N-terminus DUF3464 PF11947.8 CDJ63477.1 - 4.4 7.0 18.0 1.2 8.9 9.5 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Porph_ging PF09697.10 CDJ63477.1 - 4.6 7.8 10.5 6.3 7.4 5.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) DUF3408 PF11888.8 CDJ63477.1 - 5.8 7.1 18.2 2.9 8.0 12.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) FAM150 PF15129.6 CDJ63477.1 - 6.1 7.0 14.8 1.9 8.7 8.0 2.2 2 0 0 2 2 2 0 FAM150 family DUF2072 PF09845.9 CDJ63477.1 - 7.1 6.9 10.3 13 6.0 6.0 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein Sec62 PF03839.16 CDJ63477.1 - 8.2 5.9 12.3 2.8 7.4 5.8 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 TFB6 PF17110.5 CDJ63477.1 - 8.4 6.1 8.5 7.6 6.2 6.2 1.8 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Glt_symporter PF03616.14 CDJ63477.1 - 9 4.9 7.3 1 8.0 3.2 1.5 2 0 0 2 2 2 0 Sodium/glutamate symporter Efg1 PF10153.9 CDJ63478.1 - 0.033 14.6 9.7 0.038 14.4 9.7 1.1 1 0 0 1 1 1 0 rRNA-processing protein Efg1 LCIB_C_CA PF18599.1 CDJ63478.1 - 0.12 11.7 7.5 0.16 11.2 7.5 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Saw1 PF11561.8 CDJ63478.1 - 0.27 10.7 5.1 0.29 10.6 5.1 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 eIF3_subunit PF08597.10 CDJ63478.1 - 0.97 9.3 10.8 1.3 8.9 10.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PAT1 PF09770.9 CDJ63478.1 - 1.1 7.5 18.9 1.2 7.4 18.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HD_assoc PF13286.6 CDJ63478.1 - 1.3 9.6 10.4 2 9.0 10.4 1.4 1 0 0 1 1 1 0 Phosphohydrolase-associated domain CLN3 PF02487.17 CDJ63478.1 - 2.8 6.9 6.2 3.3 6.7 6.2 1.1 1 0 0 1 1 1 0 CLN3 protein TFIIA PF03153.13 CDJ63478.1 - 4.4 7.2 32.2 5.6 6.8 32.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ63478.1 - 4.6 7.2 6.3 5.2 7.1 6.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Thioredoxin_4 PF13462.6 CDJ63478.1 - 5.2 7.2 9.6 7.3 6.7 9.6 1.2 1 0 0 1 1 1 0 Thioredoxin Exonuc_VII_L PF02601.15 CDJ63478.1 - 5.8 6.4 16.5 6.3 6.3 16.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pro_CA PF00484.19 CDJ63478.1 - 9.4 6.5 7.2 15 5.8 7.2 1.3 1 0 0 1 1 1 0 Carbonic anhydrase Serglycin PF04360.12 CDJ63479.1 - 0.00045 20.2 0.4 0.00045 20.2 0.4 3.1 3 1 0 3 3 3 1 Serglycin IATP PF04568.12 CDJ63479.1 - 0.0088 16.5 0.1 0.0088 16.5 0.1 3.0 2 2 1 3 3 3 1 Mitochondrial ATPase inhibitor, IATP Couple_hipA PF13657.6 CDJ63479.1 - 0.094 13.4 4.6 0.082 13.6 2.3 2.2 2 1 0 2 2 2 0 HipA N-terminal domain DUF4630 PF15443.6 CDJ63479.1 - 0.25 11.5 4.1 0.45 10.7 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) V_ATPase_I PF01496.19 CDJ63479.1 - 0.28 9.1 6.9 0.35 8.7 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mac PF12464.8 CDJ63479.1 - 0.59 10.4 4.9 1.8 8.9 1.6 2.7 2 1 0 2 2 2 0 Maltose acetyltransferase Vps54 PF07928.12 CDJ63479.1 - 0.96 9.9 8.0 9.8 6.6 2.0 2.3 2 0 0 2 2 2 0 Vps54-like protein DUF4834 PF16118.5 CDJ63479.1 - 4.6 8.3 5.4 6 7.9 0.8 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Filament_head PF04732.14 CDJ63479.1 - 6.7 7.7 22.1 3.7 8.5 16.6 2.3 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Rhodanese PF00581.20 CDJ63480.1 - 6.9e-05 23.3 0.0 0.00048 20.6 0.0 2.5 1 0 0 1 1 1 1 Rhodanese-like domain Spt20 PF12090.8 CDJ63480.1 - 0.00018 21.2 1.9 0.00018 21.2 1.9 7.5 5 2 2 8 8 8 2 Spt20 family Utp14 PF04615.13 CDJ63480.1 - 7.7 4.9 49.5 0.12 11.0 14.9 3.1 3 0 0 3 3 3 0 Utp14 protein DnaJ PF00226.31 CDJ63481.1 - 1.4e-10 41.2 0.1 3.2e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain BPD_transp_2 PF02653.16 CDJ63482.1 - 0.058 12.5 2.4 0.12 11.5 2.4 1.6 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component Spt20 PF12090.8 CDJ63482.1 - 0.14 11.7 17.9 0.47 10.0 5.5 2.2 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ63482.1 - 0.72 8.7 12.3 0.78 8.6 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Ribosomal_60s PF00428.19 CDJ63482.1 - 1 10.0 29.2 3.6 8.2 10.5 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein SPX PF03105.19 CDJ63482.1 - 3.7 7.4 8.5 6.3 6.6 8.5 1.5 1 1 0 1 1 1 0 SPX domain TrbI PF03743.14 CDJ63482.1 - 5.6 6.8 12.9 0.58 10.0 5.9 2.3 2 1 0 2 2 2 0 Bacterial conjugation TrbI-like protein DUF3446 PF11928.8 CDJ63483.1 - 0.14 12.5 27.3 0.3 11.4 6.7 3.6 3 0 0 3 3 3 0 Early growth response N-terminal domain DEAD PF00270.29 CDJ63485.1 - 1.5e-25 89.9 0.1 2.3e-24 86.1 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ63485.1 - 1.2e-16 61.1 0.0 2.3e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bravo_FIGEY PF13882.6 CDJ63485.1 - 0.002 19.4 0.3 0.0036 18.6 0.3 1.3 1 0 0 1 1 1 1 Bravo-like intracellular region SPRY PF00622.28 CDJ63485.1 - 0.0026 17.9 0.0 0.94 9.6 0.0 2.4 2 0 0 2 2 2 2 SPRY domain RskA PF10099.9 CDJ63485.1 - 0.0026 18.1 12.1 0.0026 18.1 12.1 5.0 3 1 0 3 3 3 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ63485.1 - 0.05 13.2 4.5 0.077 12.6 4.5 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ63485.1 - 0.22 10.4 4.7 0.42 9.5 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Lin-8 PF03353.15 CDJ63485.1 - 0.4 10.2 2.9 0.58 9.7 2.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sporozoite_P67 PF05642.11 CDJ63485.1 - 0.63 8.1 5.0 1.1 7.2 5.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AF-4 PF05110.13 CDJ63485.1 - 0.74 7.8 10.8 1 7.4 10.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Acyltransferase PF01553.21 CDJ63486.1 - 2.5e-14 53.0 0.0 7.8e-09 35.3 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase PIH1 PF08190.12 CDJ63487.1 - 2.5e-07 30.3 0.2 1.9e-05 24.2 0.0 4.2 5 0 0 5 5 5 2 PIH1 N-terminal domain DUF4179 PF13786.6 CDJ63487.1 - 0.88 10.1 0.0 0.88 10.1 0.0 5.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4179) LptF_LptG PF03739.14 CDJ63487.1 - 1.2 7.9 5.2 3.6 6.3 5.2 1.8 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG PH PF00169.29 CDJ63488.1 - 0.053 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF1640 PF07798.11 CDJ63488.1 - 0.064 13.3 1.7 0.11 12.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TFIIA PF03153.13 CDJ63488.1 - 9.9 6.0 19.6 0.69 9.8 3.3 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ63490.1 - 0.075 13.1 0.1 0.075 13.1 0.1 2.9 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 TRAPPC9-Trs120 PF08626.11 CDJ63490.1 - 0.08 10.3 4.3 0.1 9.9 1.7 1.9 2 0 0 2 2 2 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit GTP_EFTU PF00009.27 CDJ63491.1 - 2.3e-53 180.6 0.0 3.6e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDJ63491.1 - 8.2e-41 138.8 0.0 2.7e-40 137.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ63491.1 - 6.7e-15 55.2 0.8 1.9e-14 53.8 0.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ63491.1 - 0.0003 20.9 0.0 0.031 14.4 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase NIF3 PF01784.18 CDJ63491.1 - 0.00068 19.3 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) GTP_EFTU_D4 PF14578.6 CDJ63491.1 - 0.044 13.7 0.4 0.044 13.7 0.4 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 G-alpha PF00503.20 CDJ63491.1 - 0.16 11.1 0.4 0.3 10.2 0.4 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Spt20 PF12090.8 CDJ63491.1 - 2.8 7.5 5.0 4.8 6.7 5.0 1.3 1 0 0 1 1 1 0 Spt20 family DUF4718 PF15842.5 CDJ63492.1 - 0.0012 18.7 9.0 0.0012 18.7 9.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4718) SPX PF03105.19 CDJ63493.1 - 6.5e-06 26.3 1.6 6.5e-06 26.3 1.6 2.3 2 1 1 3 3 3 1 SPX domain DUF4834 PF16118.5 CDJ63493.1 - 4e-05 24.5 5.6 0.068 14.1 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) ODV-E18 PF10717.9 CDJ63493.1 - 0.0082 16.0 0.2 0.0082 16.0 0.2 2.7 1 1 1 2 2 2 1 Occlusion-derived virus envelope protein ODV-E18 DUF1980 PF09323.10 CDJ63493.1 - 0.18 11.7 4.8 1.7 8.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) DUF3328 PF11807.8 CDJ63493.1 - 0.41 10.4 3.7 0.1 12.3 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) V_ATPase_I PF01496.19 CDJ63493.1 - 7.7 4.3 8.0 12 3.7 0.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Plasmodium_Vir PF05795.11 CDJ63494.1 - 0.0034 16.9 11.1 0.0034 16.9 11.1 1.4 2 0 0 2 2 2 1 Plasmodium vivax Vir protein PHC2_SAM_assoc PF16616.5 CDJ63494.1 - 0.0078 17.0 27.2 0.0078 17.0 27.2 2.2 2 0 0 2 2 2 1 Unstructured region on Polyhomeotic-like protein 1 and 2 SR-25 PF10500.9 CDJ63494.1 - 0.013 15.1 33.2 0.013 15.1 33.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1645 PF07816.11 CDJ63494.1 - 0.018 15.6 16.9 0.018 15.6 16.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) CDC45 PF02724.14 CDJ63494.1 - 0.02 13.2 15.2 0.02 13.2 15.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SPX PF03105.19 CDJ63494.1 - 0.03 14.2 25.7 0.034 14.1 25.7 1.0 1 0 0 1 1 1 0 SPX domain DDRGK PF09756.9 CDJ63494.1 - 0.099 12.2 25.1 0.13 11.9 25.1 1.1 1 0 0 1 1 1 0 DDRGK domain MDM10 PF12519.8 CDJ63494.1 - 0.13 11.1 13.9 0.15 10.9 13.9 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Tim54 PF11711.8 CDJ63494.1 - 0.18 10.6 14.5 0.28 9.9 14.5 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.9 CDJ63494.1 - 0.23 9.7 28.1 0.25 9.5 28.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cwf_Cwc_15 PF04889.12 CDJ63494.1 - 0.26 11.0 23.0 0.43 10.3 23.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FHIPEP PF00771.20 CDJ63494.1 - 0.27 9.6 5.8 0.43 9.0 5.8 1.4 1 0 0 1 1 1 0 FHIPEP family Dicty_REP PF05086.12 CDJ63494.1 - 0.28 9.1 9.9 0.29 9.1 9.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SpoIIP PF07454.11 CDJ63494.1 - 0.37 10.2 17.3 0.6 9.5 17.3 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) U1snRNP70_N PF12220.8 CDJ63494.1 - 0.46 11.2 14.9 1.3 9.7 14.9 1.8 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pkinase_fungal PF17667.1 CDJ63494.1 - 0.67 8.7 10.7 0.96 8.1 10.7 1.2 1 0 0 1 1 1 0 Fungal protein kinase Exonuc_VII_L PF02601.15 CDJ63494.1 - 1.3 8.5 17.4 1.4 8.4 17.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4770 PF15994.5 CDJ63494.1 - 1.3 9.2 16.5 2.1 8.6 16.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4407 PF14362.6 CDJ63494.1 - 1.3 8.3 19.8 0.086 12.2 14.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Hamartin PF04388.12 CDJ63494.1 - 1.6 7.3 21.3 2.1 6.9 21.3 1.2 1 0 0 1 1 1 0 Hamartin protein VIR_N PF15912.5 CDJ63494.1 - 2.4 7.7 10.8 3.3 7.2 10.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal GvpL_GvpF PF06386.11 CDJ63494.1 - 3 7.7 16.0 4.1 7.2 16.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF LMBR1 PF04791.16 CDJ63494.1 - 3.1 6.6 6.3 3.2 6.6 6.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein NEMP PF10225.9 CDJ63494.1 - 3.3 7.3 11.6 7.2 6.2 11.6 1.6 1 0 0 1 1 1 0 NEMP family SLC12 PF03522.15 CDJ63494.1 - 3.5 6.5 23.3 4.7 6.1 23.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RPN2_C PF18004.1 CDJ63494.1 - 3.5 7.5 19.7 6.1 6.8 19.7 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF853 PF05872.12 CDJ63494.1 - 3.8 6.0 15.1 6 5.3 15.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) eIF-3_zeta PF05091.12 CDJ63494.1 - 4.4 6.2 26.6 5.7 5.8 26.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Smg8_Smg9 PF10220.9 CDJ63494.1 - 5.1 5.3 21.3 6.8 4.9 21.3 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Hid1 PF12722.7 CDJ63494.1 - 5.5 5.0 23.1 5.8 4.9 23.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DcuA_DcuB PF03605.14 CDJ63494.1 - 5.5 5.8 6.7 9.4 5.0 6.7 1.4 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter GNAT_acetyltr_2 PF13718.6 CDJ63494.1 - 5.6 6.3 13.2 8.1 5.8 13.2 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Mem_trans PF03547.18 CDJ63494.1 - 6.1 5.1 12.7 8.4 4.7 12.7 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF4638 PF15472.6 CDJ63494.1 - 6.5 6.4 17.7 8.8 6.0 17.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF4746 PF15928.5 CDJ63494.1 - 7.4 5.9 14.4 9.6 5.5 14.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) HCO3_cotransp PF00955.21 CDJ63494.1 - 9.7 4.9 6.5 13 4.5 6.5 1.3 1 0 0 1 1 1 0 HCO3- transporter family SR-25 PF10500.9 CDJ63495.1 - 0.0079 15.8 12.9 0.0079 15.8 12.9 2.4 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 CDJ63495.1 - 0.008 15.9 8.2 0.017 14.8 8.2 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 SOBP PF15279.6 CDJ63495.1 - 0.19 12.3 6.3 0.43 11.1 6.3 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein Suf PF05843.14 CDJ63495.1 - 0.49 10.3 11.8 1.2 9.0 11.8 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) rRNA_processing PF08524.11 CDJ63495.1 - 2.9 7.9 18.0 7.3 6.6 18.0 1.7 1 0 0 1 1 1 0 rRNA processing LAP1C PF05609.12 CDJ63495.1 - 3.3 6.7 17.5 6.9 5.6 17.5 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MID_MedPIWI PF18296.1 CDJ63495.1 - 3.4 7.4 10.9 7.9 6.2 10.9 1.7 1 0 0 1 1 1 0 MID domain of medPIWI LCIB_C_CA PF18599.1 CDJ63495.1 - 5.3 6.3 7.5 18 4.5 7.5 1.9 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Enkurin PF13864.6 CDJ63496.1 - 3e-05 24.4 11.9 6e-05 23.4 11.9 1.5 1 1 0 1 1 1 1 Calmodulin-binding Collagen PF01391.18 CDJ63496.1 - 3.9 7.3 111.4 0.24 11.2 37.9 5.1 2 2 1 3 3 3 0 Collagen triple helix repeat (20 copies) Abhydrolase_1 PF00561.20 CDJ63497.1 - 3.5e-26 92.4 3.0 4.2e-26 92.1 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold SUIM_assoc PF16619.5 CDJ63497.1 - 0.014 15.4 3.8 0.014 15.4 3.8 5.6 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Ndr PF03096.14 CDJ63497.1 - 0.023 13.4 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Ndr family TCP PF03634.13 CDJ63497.1 - 0.8 10.2 17.3 0.087 13.4 7.6 3.0 3 0 0 3 3 3 0 TCP family transcription factor SelP_N PF04592.14 CDJ63497.1 - 2.8 7.3 23.8 0.12 11.8 16.2 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Presenilin PF01080.17 CDJ63497.1 - 5 5.8 13.2 0.047 12.5 2.0 2.4 3 0 0 3 3 3 0 Presenilin Gti1_Pac2 PF09729.9 CDJ63497.1 - 5.5 7.0 7.3 44 4.1 5.5 2.5 2 1 0 2 2 2 0 Gti1/Pac2 family V_ATPase_I PF01496.19 CDJ63497.1 - 8 4.2 15.5 0.13 10.2 7.3 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CCSAP PF15748.5 CDJ63497.1 - 9.2 6.3 23.3 0.087 13.0 9.8 2.9 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated Rad51 PF08423.11 CDJ63498.1 - 1.4e-18 67.1 3.5 1.2e-15 57.5 3.8 3.2 2 1 0 2 2 2 1 Rad51 RecA PF00154.21 CDJ63498.1 - 6.9e-07 29.0 0.3 0.0016 18.0 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_25 PF13481.6 CDJ63498.1 - 1.5e-06 27.9 0.9 1.5e-06 27.9 0.9 3.3 3 1 0 3 3 3 1 AAA domain ATPase PF06745.13 CDJ63498.1 - 0.0014 18.0 0.1 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_33 PF13671.6 CDJ63498.1 - 0.0079 16.4 5.4 0.34 11.1 0.0 3.9 3 1 1 4 4 4 1 AAA domain NACHT PF05729.12 CDJ63498.1 - 0.023 14.6 7.7 0.031 14.2 3.4 2.7 2 1 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 CDJ63498.1 - 0.027 14.7 0.1 1.9 8.7 0.3 3.0 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 CDJ63498.1 - 0.11 12.0 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DnaB_C PF03796.15 CDJ63498.1 - 0.13 11.5 0.1 0.36 10.1 0.1 1.7 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain Zn_peptidase PF04228.13 CDJ63499.1 - 1.6 8.1 16.5 0.085 12.3 10.8 1.7 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Dicty_CTDC PF00526.18 CDJ63499.1 - 2 8.4 6.3 0.52 10.3 0.6 2.3 2 0 0 2 2 2 0 Dictyostelium (slime mold) repeat SOBP PF15279.6 CDJ63499.1 - 8.1 7.0 28.8 1.7 9.2 22.8 2.0 2 0 0 2 2 2 0 Sine oculis-binding protein Rieske_3 PF18465.1 CDJ63501.1 - 0.074 13.3 1.8 0.079 13.2 1.8 1.2 1 0 0 1 1 1 0 Rieske 3Fe-4S RskA PF10099.9 CDJ63501.1 - 0.19 12.0 2.8 0.18 12.1 2.8 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA FAM150 PF15129.6 CDJ63501.1 - 0.34 11.1 5.5 0.35 11.0 5.5 1.1 1 0 0 1 1 1 0 FAM150 family DUF2722 PF10846.8 CDJ63501.1 - 0.57 9.1 12.9 0.51 9.2 12.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4175 PF13779.6 CDJ63501.1 - 1.2 7.0 9.4 0.92 7.3 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MscS_TM PF12794.7 CDJ63501.1 - 1.6 7.5 3.0 1.5 7.6 3.0 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Med15 PF09606.10 CDJ63501.1 - 1.7 7.2 14.7 1.5 7.4 14.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ63501.1 - 3.1 7.7 14.8 2.7 7.9 14.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5349 PF17298.2 CDJ63501.1 - 7.7 6.2 9.9 7.5 6.2 9.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) SUIM_assoc PF16619.5 CDJ63502.1 - 0.0064 16.5 2.8 0.0064 16.5 2.8 33.6 15 9 3 18 18 18 4 Unstructured region C-term to UIM in Ataxin3 OMPdecase PF00215.24 CDJ63503.1 - 2.8e-08 33.6 9.0 1.8e-07 31.0 9.0 2.1 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF3446 PF11928.8 CDJ63504.1 - 0.0072 16.6 0.6 0.0072 16.6 0.6 1.8 2 0 0 2 2 2 1 Early growth response N-terminal domain Chorion_2 PF03964.15 CDJ63504.1 - 0.089 13.6 0.6 0.089 13.6 0.6 1.9 2 0 0 2 2 2 0 Chorion family 2 Proteasome PF00227.26 CDJ63505.1 - 6.6e-17 61.6 0.0 7.8e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit TFIIA PF03153.13 CDJ63507.1 - 9.6 6.1 24.1 14 5.6 24.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 CDJ63508.1 - 0.0044 15.5 9.0 0.0055 15.2 9.0 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ63508.1 - 0.0051 15.8 10.8 0.006 15.6 10.8 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) TFIIA PF03153.13 CDJ63508.1 - 0.0077 16.3 45.6 0.0093 16.0 45.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ63508.1 - 0.0078 15.0 15.4 0.0087 14.9 15.4 1.2 1 0 0 1 1 1 1 Presenilin AAA_23 PF13476.6 CDJ63508.1 - 0.0086 16.6 10.6 0.0086 16.6 10.6 1.2 1 0 0 1 1 1 1 AAA domain Suf PF05843.14 CDJ63508.1 - 0.019 15.0 16.0 0.021 14.8 16.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SLC12 PF03522.15 CDJ63508.1 - 0.02 13.9 10.2 0.019 14.0 10.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PAT1 PF09770.9 CDJ63508.1 - 0.024 12.9 25.3 0.024 12.9 25.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 CDJ63508.1 - 0.036 13.0 19.1 0.039 12.9 19.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM176 PF14851.6 CDJ63508.1 - 0.037 13.7 5.9 0.052 13.2 5.9 1.4 1 0 0 1 1 1 0 FAM176 family DUF913 PF06025.12 CDJ63508.1 - 0.057 12.4 8.6 0.06 12.3 8.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SprA-related PF12118.8 CDJ63508.1 - 0.07 12.3 32.2 0.09 11.9 32.2 1.2 1 0 0 1 1 1 0 SprA-related family MDM10 PF12519.8 CDJ63508.1 - 0.071 12.0 10.9 0.092 11.6 10.9 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Peptidase_S49_N PF08496.10 CDJ63508.1 - 0.072 13.2 13.0 0.1 12.7 13.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Folate_carrier PF01770.18 CDJ63508.1 - 0.081 11.7 7.2 0.099 11.4 7.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier Herpes_glycop PF01528.16 CDJ63508.1 - 0.13 11.1 4.9 0.16 10.8 4.9 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M EIF4E-T PF10477.9 CDJ63508.1 - 0.13 11.0 21.9 0.14 11.0 21.9 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E LRR19-TM PF15176.6 CDJ63508.1 - 0.14 12.2 3.0 0.27 11.3 3.0 1.5 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain JUPITER PF17054.5 CDJ63508.1 - 0.15 11.5 4.4 0.18 11.2 4.4 1.0 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter CSG2 PF16965.5 CDJ63508.1 - 0.16 10.9 7.5 0.16 10.9 7.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator FPN1 PF06963.12 CDJ63508.1 - 0.17 10.4 6.3 0.23 10.0 6.3 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) SpoIIP PF07454.11 CDJ63508.1 - 0.17 11.3 16.9 0.21 11.0 16.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TERB2 PF15101.6 CDJ63508.1 - 0.2 11.7 21.9 0.045 13.8 19.0 1.5 2 0 0 2 2 1 0 Telomere-associated protein TERB2 Hid1 PF12722.7 CDJ63508.1 - 0.21 9.7 10.8 0.18 9.9 10.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein V_ATPase_I PF01496.19 CDJ63508.1 - 0.24 9.3 15.7 0.28 9.1 15.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 CDJ63508.1 - 0.24 11.2 14.7 0.31 10.8 14.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1682 PF07946.14 CDJ63508.1 - 0.41 9.8 13.5 0.46 9.6 13.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4446 PF14584.6 CDJ63508.1 - 0.44 10.5 7.2 0.74 9.8 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2828 PF11443.8 CDJ63508.1 - 0.49 8.4 16.5 0.57 8.2 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3408 PF11888.8 CDJ63508.1 - 0.49 10.5 18.2 0.68 10.1 18.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Nucleoside_tran PF01733.18 CDJ63508.1 - 0.54 9.6 3.6 0.66 9.3 3.6 1.1 1 0 0 1 1 1 0 Nucleoside transporter PPL5 PF18168.1 CDJ63508.1 - 0.55 9.5 13.2 0.91 8.8 13.2 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DUF2232 PF09991.9 CDJ63508.1 - 0.55 9.4 6.3 0.8 8.8 6.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Membralin PF09746.9 CDJ63508.1 - 0.78 8.7 9.6 0.88 8.5 9.6 1.2 1 0 0 1 1 1 0 Tumour-associated protein YABBY PF04690.13 CDJ63508.1 - 0.89 10.1 12.7 0.39 11.3 10.5 1.6 2 0 0 2 2 1 0 YABBY protein Otopetrin PF03189.13 CDJ63508.1 - 0.97 8.2 8.7 1.3 7.7 8.7 1.2 1 0 0 1 1 1 0 Otopetrin Connexin PF00029.19 CDJ63508.1 - 0.99 9.1 14.3 1.2 8.8 14.3 1.2 1 0 0 1 1 1 0 Connexin EIIBC-GUT_N PF03612.14 CDJ63508.1 - 1.1 9.0 13.8 1.6 8.5 13.8 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RPA43_OB PF17875.1 CDJ63508.1 - 1.1 9.9 11.1 1.6 9.3 11.1 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Coilin_N PF15862.5 CDJ63508.1 - 1.1 9.0 19.3 0.21 11.4 14.7 2.0 2 0 0 2 2 2 0 Coilin N-terminus Peptidase_C37 PF05416.12 CDJ63508.1 - 1.2 7.6 8.8 1.1 7.7 8.8 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase HCO3_cotransp PF00955.21 CDJ63508.1 - 1.7 7.4 9.2 2.2 7.0 9.2 1.1 1 0 0 1 1 1 0 HCO3- transporter family AAT PF03417.16 CDJ63508.1 - 1.7 8.3 11.8 2.3 7.9 11.8 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase PIP5K PF01504.18 CDJ63508.1 - 2 7.6 15.7 2.6 7.2 15.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase O-antigen_lig PF13425.6 CDJ63508.1 - 2.6 6.8 6.9 2.8 6.7 6.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Oleosin PF01277.17 CDJ63508.1 - 2.9 7.7 11.4 9 6.1 11.4 1.8 1 1 0 1 1 1 0 Oleosin Peptidase_S15 PF02129.18 CDJ63508.1 - 2.9 7.4 17.8 3.7 7.1 17.8 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Tim54 PF11711.8 CDJ63508.1 - 2.9 6.6 16.1 3.9 6.2 16.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SR-25 PF10500.9 CDJ63508.1 - 3 7.4 23.2 0.42 10.2 5.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AMP-binding PF00501.28 CDJ63508.1 - 3 6.3 7.8 3.6 6.1 7.8 1.0 1 0 0 1 1 1 0 AMP-binding enzyme Paramyxo_ncap PF00973.19 CDJ63508.1 - 3.5 6.4 13.1 4.2 6.2 13.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DcuC PF03606.15 CDJ63508.1 - 4.6 5.6 9.4 7.8 4.8 9.4 1.4 1 1 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Rrn6 PF10214.9 CDJ63508.1 - 5.3 5.4 23.8 6.9 5.0 23.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Rxt3 PF08642.10 CDJ63508.1 - 6.3 7.6 10.9 5 7.9 9.3 1.6 2 0 0 2 2 1 0 Histone deacetylation protein Rxt3 Pal1 PF08316.11 CDJ63508.1 - 7.6 7.3 9.4 2.4 8.9 6.9 1.6 2 0 0 2 2 1 0 Pal1 cell morphology protein RskA PF10099.9 CDJ63508.1 - 8.3 6.7 37.5 1e+02 3.1 37.6 2.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF3537 PF12056.8 CDJ63508.1 - 8.8 5.0 14.5 13 4.5 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) MMU163 PF17119.5 CDJ63508.1 - 9.7 5.3 11.7 1.5 7.9 8.1 1.5 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis rve PF00665.26 CDJ63509.1 - 8.8e-09 35.6 0.0 1.8e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ63509.1 - 3.3e-08 33.3 0.0 7.4e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 CDJ63510.1 - 2.2e-28 98.2 0.1 4e-28 97.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ63510.1 - 4.4e-28 97.6 0.0 8e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ63510.1 - 4.6e-09 36.3 1.5 9.4e-09 35.3 1.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ63510.1 - 5.5e-09 35.9 0.0 9.6e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 CDJ63510.1 - 0.03 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DEAD PF00270.29 CDJ63514.1 - 5.7e-45 153.2 0.1 8e-45 152.7 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ63514.1 - 6.2e-29 100.6 1.9 1.1e-28 99.8 0.4 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CDJ63514.1 - 0.044 13.1 0.1 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MMR_HSR1 PF01926.23 CDJ63515.1 - 3.9e-38 130.0 0.0 5.7e-19 68.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 CDJ63515.1 - 2.9e-24 85.2 0.0 8.3e-24 83.7 0.0 1.8 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 CDJ63515.1 - 3.8e-14 52.5 0.1 3.2e-09 36.5 0.0 3.2 3 1 0 3 3 3 2 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ63515.1 - 1e-10 42.0 2.8 0.00093 19.3 0.1 4.4 3 1 1 4 4 4 2 Dynamin family GTP_EFTU PF00009.27 CDJ63515.1 - 1e-10 41.5 0.7 2.5e-05 23.9 0.1 4.5 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CDJ63515.1 - 2.6e-10 40.0 0.1 0.0004 19.8 0.1 2.7 2 1 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 CDJ63515.1 - 9.8e-07 28.8 0.7 0.034 14.1 0.0 4.4 5 0 0 5 5 5 2 RsgA GTPase Roc PF08477.13 CDJ63515.1 - 1.3e-05 25.4 0.1 0.051 13.8 0.0 3.3 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CDJ63515.1 - 3.5e-05 23.3 0.0 0.069 12.5 0.0 2.7 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Ras PF00071.22 CDJ63515.1 - 0.00025 20.7 0.0 0.12 12.0 0.0 3.5 3 1 0 3 3 3 1 Ras family TniB PF05621.11 CDJ63515.1 - 0.0023 17.4 0.0 0.24 10.8 0.0 2.6 3 0 0 3 3 3 1 Bacterial TniB protein ABC_tran PF00005.27 CDJ63515.1 - 0.0089 16.6 0.0 2.2 8.8 0.0 2.7 2 0 0 2 2 2 1 ABC transporter SRPRB PF09439.10 CDJ63515.1 - 0.026 14.0 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Arf PF00025.21 CDJ63515.1 - 0.052 13.0 0.1 0.51 9.8 0.1 2.5 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_15 PF13175.6 CDJ63515.1 - 0.16 11.7 0.0 6 6.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.25 CDJ63516.1 - 1e-60 205.4 0.0 1.7e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63516.1 - 4.7e-36 124.4 0.0 7.8e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ63516.1 - 0.00079 18.3 0.0 0.0025 16.7 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase YlqD PF11068.8 CDJ63517.1 - 0.14 12.5 2.7 0.26 11.7 2.7 1.4 1 0 0 1 1 1 0 YlqD protein UPF0113_N PF17833.1 CDJ63518.1 - 2.9e-26 91.8 0.1 4.3e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CDJ63518.1 - 2.7e-16 59.6 0.0 4.4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain DEAD PF00270.29 CDJ63519.1 - 1.7e-27 96.3 0.1 5.8e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ63519.1 - 8.2e-24 84.1 0.0 2.5e-23 82.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ63519.1 - 0.02 14.9 0.0 0.13 12.2 0.0 2.5 2 2 1 3 3 3 0 Type III restriction enzyme, res subunit Cir_N PF10197.9 CDJ63520.1 - 6.4e-12 45.5 13.0 6.4e-12 45.5 13.0 4.3 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Slu7 PF11708.8 CDJ63520.1 - 0.84 9.3 19.3 2.3 7.9 12.7 3.0 2 1 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor HSP70 PF00012.20 CDJ63520.1 - 5.8 5.0 10.3 8.6 4.4 10.3 1.2 1 0 0 1 1 1 0 Hsp70 protein Penicil_amidase PF01804.18 CDJ63522.1 - 3.4e-104 350.2 0.0 8.6e-104 348.9 0.0 1.5 1 1 0 1 1 1 1 Penicillin amidase BRCT_2 PF16589.5 CDJ63523.1 - 0.043 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Fucose_iso_N1 PF07881.12 CDJ63523.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain EF-hand_6 PF13405.6 CDJ63524.1 - 9.8e-11 40.7 0.0 0.00045 19.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDJ63524.1 - 1.9e-10 39.5 0.0 0.00077 18.8 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDJ63524.1 - 3.2e-09 37.1 0.0 0.0029 18.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ63524.1 - 6.5e-06 25.9 0.0 0.024 14.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CDJ63524.1 - 0.00086 19.6 0.1 1.4 9.3 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ63524.1 - 0.0052 16.2 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 EF hand Caleosin PF05042.13 CDJ63524.1 - 0.18 11.7 0.0 0.62 10.0 0.0 1.8 2 0 0 2 2 2 0 Caleosin related protein ASH PF15780.5 CDJ63525.1 - 6.9e-14 51.8 7.2 0.4 10.9 0.0 8.4 9 0 0 9 9 9 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CDJ63525.1 - 9.5e-05 22.5 0.1 0.044 14.0 0.0 4.0 4 0 0 4 4 4 1 Flagellar-associated PapD-like TMEM131_like PF12371.8 CDJ63525.1 - 0.0015 18.7 0.6 21 5.5 0.0 5.7 6 0 0 6 6 6 1 Transmembrane protein 131-like DUF1573 PF07610.11 CDJ63525.1 - 0.0063 16.5 2.3 30 4.7 0.0 5.4 5 0 0 5 5 5 1 Protein of unknown function (DUF1573) MITF_TFEB_C_3_N PF15951.5 CDJ63526.1 - 0.00023 21.8 3.9 0.00062 20.4 3.9 1.7 1 0 0 1 1 1 1 MITF/TFEB/TFEC/TFE3 N-terminus Pox_A12 PF04651.13 CDJ63526.1 - 5.6 7.0 7.0 0.37 10.8 1.6 1.8 2 0 0 2 2 2 0 Poxvirus A12 protein DUF1573 PF07610.11 CDJ63527.1 - 0.0014 18.7 0.0 16 5.6 0.0 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF1573) PapD-like PF14874.6 CDJ63527.1 - 0.0087 16.2 0.0 6.6 7.0 0.0 3.0 3 0 0 3 3 3 2 Flagellar-associated PapD-like ASH PF15780.5 CDJ63528.1 - 2.2e-09 37.4 0.0 4.2e-08 33.3 0.0 2.2 2 1 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CDJ63528.1 - 0.00012 22.1 0.0 0.0048 17.0 0.0 2.2 2 0 0 2 2 2 1 Flagellar-associated PapD-like Motile_Sperm PF00635.26 CDJ63528.1 - 0.00015 21.6 0.0 0.042 13.7 0.0 2.7 3 0 0 3 3 3 2 MSP (Major sperm protein) domain ASH PF15780.5 CDJ63529.1 - 2.5e-06 27.6 0.1 0.009 16.2 0.0 3.0 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD_N PF00345.20 CDJ63529.1 - 0.1 12.5 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Cupredoxin_1 PF13473.6 CDJ63529.1 - 0.13 12.3 0.2 1.2 9.2 0.1 2.5 2 1 0 2 2 2 0 Cupredoxin-like domain cEGF PF12662.7 CDJ63530.1 - 0.036 14.0 0.7 0.036 14.0 0.7 7.8 8 0 0 8 8 8 0 Complement Clr-like EGF-like EGF_3 PF12947.7 CDJ63530.1 - 6.3 7.1 60.8 0.055 13.7 2.5 8.6 8 2 0 8 8 8 0 EGF domain Peptidase_M24 PF00557.24 CDJ63531.1 - 7.8e-38 130.3 0.0 1.1e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 CDJ63531.1 - 8.1e-31 107.3 0.0 1.2e-29 103.5 0.0 2.7 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CDJ63531.1 - 1.3e-24 86.0 0.1 8e-24 83.5 0.0 2.5 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CDJ63531.1 - 5.2e-20 72.4 0.4 1.1e-15 58.5 0.0 2.8 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain zf-U1 PF06220.12 CDJ63532.1 - 0.00043 20.0 0.5 0.00043 20.0 0.5 2.0 2 0 0 2 2 2 1 U1 zinc finger WW PF00397.26 CDJ63532.1 - 0.032 14.3 0.1 0.09 12.9 0.1 1.8 1 0 0 1 1 1 0 WW domain DUF3439 PF11921.8 CDJ63532.1 - 0.3 11.1 1.7 1 9.4 1.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ribosomal_S2 PF00318.20 CDJ63532.1 - 0.44 9.8 5.7 0.071 12.3 0.9 2.0 2 0 0 2 2 2 0 Ribosomal protein S2 DUF1612 PF07756.12 CDJ63532.1 - 8.7 6.6 12.8 0.43 10.8 2.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) zf-RING_2 PF13639.6 CDJ63534.1 - 3e-05 24.3 13.7 3e-05 24.3 13.7 3.5 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ63534.1 - 0.00011 22.0 10.0 0.00011 22.0 10.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ63534.1 - 0.00024 20.9 14.2 0.00024 20.9 14.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 CDJ63534.1 - 0.00066 19.7 2.0 0.00066 19.7 2.0 4.7 1 1 4 5 5 5 2 Seven in absentia protein family zf-C3HC4_2 PF13923.6 CDJ63534.1 - 0.0018 18.1 12.8 0.0018 18.1 12.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ63534.1 - 0.0023 17.9 13.5 0.01 15.9 13.5 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CDJ63534.1 - 0.01 15.9 5.2 0.01 15.9 5.2 2.1 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-TRAF PF02176.18 CDJ63534.1 - 0.013 16.1 5.8 0.013 16.1 5.8 4.1 2 1 3 5 5 4 0 TRAF-type zinc finger zf-C3HC4_4 PF15227.6 CDJ63534.1 - 0.02 15.0 12.5 0.02 15.0 12.5 2.4 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-TRAF_2 PF15965.5 CDJ63534.1 - 0.075 13.5 21.7 0.053 14.0 5.1 3.2 1 1 2 3 3 3 0 TRAF-like zinc-finger zf_C2H2_6 PF18450.1 CDJ63534.1 - 7.4 6.4 11.4 9.7 6.0 0.2 3.4 3 1 0 3 3 3 0 Zinc Finger domain OTU PF02338.19 CDJ63535.1 - 7.1e-12 45.9 0.0 1.5e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDJ63535.1 - 0.0021 17.5 0.4 0.86 9.0 0.4 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain ATP-synt_C PF00137.21 CDJ63536.1 - 3e-27 94.7 30.5 2.5e-15 56.6 7.5 2.5 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 CDJ63536.1 - 0.18 12.3 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 IMCp PF12314.8 CDJ63537.1 - 1.4e-24 86.2 21.9 1.4e-24 86.2 21.9 3.7 1 1 2 3 3 3 3 Inner membrane complex protein ParA PF10609.9 CDJ63538.1 - 1.6e-69 234.1 0.0 2.8e-46 158.0 0.0 2.2 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 CDJ63538.1 - 6e-18 64.8 0.5 1.8e-17 63.3 0.0 2.1 3 0 0 3 3 3 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 CDJ63538.1 - 4.4e-10 39.7 0.0 6.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF971 PF06155.12 CDJ63538.1 - 2.6e-07 31.2 0.0 7.9e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF971) MipZ PF09140.11 CDJ63538.1 - 8.9e-07 28.4 0.0 1.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 CDJ63538.1 - 1.7e-06 28.0 0.1 9.3e-06 25.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 CDJ63538.1 - 0.00083 18.6 0.1 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 Anion-transporting ATPase VirC1 PF07015.11 CDJ63538.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein APS_kinase PF01583.20 CDJ63538.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase CLP1_P PF16575.5 CDJ63538.1 - 0.13 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Tox-REase-2 PF15646.6 CDJ63539.1 - 0.0039 17.4 0.3 0.005 17.0 0.3 1.1 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 2 BAR_2 PF10455.9 CDJ63539.1 - 0.0088 15.2 1.0 0.01 15.0 1.0 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking XPC-binding PF09280.11 CDJ63539.1 - 0.027 14.2 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 XPC-binding domain Lysozyme_like PF13702.6 CDJ63540.1 - 0.06 13.0 0.0 0.073 12.8 0.0 1.1 1 0 0 1 1 1 0 Lysozyme-like SR-25 PF10500.9 CDJ63541.1 - 0.0001 22.0 13.0 0.0001 22.0 13.0 2.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein HBS1_N PF08938.10 CDJ63541.1 - 0.001 19.3 0.0 0.0032 17.7 0.0 1.9 1 0 0 1 1 1 1 HBS1 N-terminus IMUP PF15761.5 CDJ63541.1 - 0.012 16.3 12.1 0.034 14.8 12.1 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein Aquarius_N PF16399.5 CDJ63542.1 - 4.7e-136 454.9 40.5 2.7e-63 214.3 0.0 6.7 6 2 0 6 6 5 4 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 CDJ63542.1 - 1.8e-13 50.9 0.9 1.8e-13 50.9 0.9 5.5 4 2 1 5 5 3 2 AAA domain AAA_19 PF13245.6 CDJ63542.1 - 5.2e-06 26.8 0.0 2.8e-05 24.5 0.0 2.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ63542.1 - 0.00011 22.2 0.0 0.00011 22.2 0.0 4.4 5 0 0 5 5 3 1 Type III restriction enzyme, res subunit DUF2722 PF10846.8 CDJ63542.1 - 0.00015 20.9 16.1 0.00015 20.9 16.1 7.6 7 1 0 7 7 6 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ63542.1 - 0.00064 19.8 8.1 0.00064 19.8 8.1 5.7 5 2 0 5 5 2 1 Suppressor of forked protein (Suf) ATPase PF06745.13 CDJ63542.1 - 0.00073 18.9 0.0 0.0028 17.0 0.0 1.9 1 0 0 1 1 1 1 KaiC TAF4 PF05236.14 CDJ63542.1 - 0.00088 19.1 15.4 0.00088 19.1 15.4 6.6 5 3 0 5 5 2 1 Transcription initiation factor TFIID component TAF4 family AAA_22 PF13401.6 CDJ63542.1 - 0.00092 19.5 0.0 0.00092 19.5 0.0 4.4 5 0 0 5 5 3 1 AAA domain AAA_25 PF13481.6 CDJ63542.1 - 0.0014 18.3 0.0 0.008 15.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CDJ63542.1 - 0.0044 16.7 0.0 0.0044 16.7 0.0 3.9 4 0 0 4 4 1 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 CDJ63542.1 - 0.011 15.8 0.0 0.048 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ63542.1 - 0.73 10.3 0.0 0.73 10.3 0.0 3.3 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDJ63542.1 - 2.2 8.9 0.0 2.2 8.9 0.0 3.5 4 0 0 4 4 2 0 AAA domain AAA_24 PF13479.6 CDJ63542.1 - 2.6 7.7 0.0 2.6 7.7 0.0 3.5 4 1 0 4 4 1 0 AAA domain Neur_chan_memb PF02932.16 CDJ63543.1 - 0.52 10.3 18.7 0.76 9.8 18.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hamartin PF04388.12 CDJ63543.1 - 1.6 7.3 22.1 1.8 7.2 22.1 1.0 1 0 0 1 1 1 0 Hamartin protein SLC12 PF03522.15 CDJ63543.1 - 4.7 6.1 24.6 6.3 5.7 24.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 CDJ63543.1 - 5.4 5.2 22.0 7.6 4.7 22.0 1.3 1 0 0 1 1 1 0 CDC45-like protein ADIP PF11559.8 CDJ63543.1 - 9.4 6.3 42.3 8 6.5 2.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Hid1 PF12722.7 CDJ63543.1 - 9.7 4.2 25.2 12 3.8 25.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AAA_12 PF13087.6 CDJ63544.1 - 2.3e-19 69.8 0.0 9e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 CDJ63544.1 - 0.19 11.6 1.2 12 5.9 0.0 2.5 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain CEP44 PF15007.6 CDJ63546.1 - 1.8e-18 67.0 0.0 2.6e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 CAF1 PF04857.20 CDJ63547.1 - 0.25 10.5 7.4 0.35 10.0 7.4 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF572 PF04502.13 CDJ63547.1 - 2.2 7.8 18.0 2.6 7.6 18.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) TMEM154 PF15102.6 CDJ63547.1 - 2.8 7.8 5.6 0.48 10.3 0.2 2.1 2 0 0 2 2 2 0 TMEM154 protein family LptF_LptG PF03739.14 CDJ63547.1 - 4.1 6.2 4.7 5.7 5.7 4.7 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Afi1 PF07792.12 CDJ63547.1 - 4.2 7.9 13.8 6.8 7.2 1.2 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF966 PF06136.13 CDJ63547.1 - 4.4 6.9 18.8 5.5 6.6 18.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4770 PF15994.5 CDJ63547.1 - 7.7 6.7 21.1 9.4 6.4 10.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) BAF1_ABF1 PF04684.13 CDJ63547.1 - 8.5 5.3 20.3 13 4.7 20.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor EMC3_TMCO1 PF01956.16 CDJ63547.1 - 8.9 6.0 24.7 3.2 7.5 14.0 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Connexin PF00029.19 CDJ63547.1 - 9.5 5.9 15.3 1.5 8.5 1.2 2.1 2 0 0 2 2 2 0 Connexin Dehydrin PF00257.19 CDJ63548.1 - 0.2 12.2 12.4 0.35 11.4 2.7 2.2 1 1 1 2 2 2 0 Dehydrin IMUP PF15761.5 CDJ63548.1 - 0.43 11.3 11.6 1.3 9.7 2.9 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ63548.1 - 1.8 8.1 11.1 1.4 8.4 3.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SARAF PF06682.12 CDJ63550.1 - 1.7 8.2 24.5 0.16 11.6 15.3 2.2 1 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis PRP38 PF03371.15 CDJ63553.1 - 2e-49 167.8 0.0 3.4e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 PRP38 family E_Pc_C PF06752.12 CDJ63554.1 - 0.01 15.9 12.8 0.01 15.9 12.8 7.4 6 1 1 7 7 7 0 Enhancer of Polycomb C-terminus Comm PF15957.5 CDJ63554.1 - 0.1 12.9 0.1 0.1 12.9 0.1 3.9 4 1 0 4 4 4 0 Commissureless DUF572 PF04502.13 CDJ63555.1 - 0.063 12.9 20.9 0.096 12.3 20.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.13 CDJ63555.1 - 4.2 7.3 64.8 0.22 11.5 22.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Prp19 PF08606.11 CDJ63556.1 - 1.3e-17 63.5 6.2 1.3e-17 63.5 6.2 2.6 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.32 CDJ63556.1 - 4.7e-08 33.6 0.1 1.9e-05 25.3 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat TBCA PF02970.16 CDJ63556.1 - 0.026 14.9 1.3 0.051 13.9 1.3 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor A Cep57_CLD_2 PF14197.6 CDJ63556.1 - 0.12 12.5 4.6 0.27 11.3 4.6 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 GED PF02212.18 CDJ63556.1 - 0.53 10.5 3.7 1 9.6 3.7 1.4 1 0 0 1 1 1 0 Dynamin GTPase effector domain Secretin_N_2 PF07655.13 CDJ63556.1 - 0.83 10.2 13.6 1.9 9.1 13.6 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Sporozoite_P67 PF05642.11 CDJ63556.1 - 3.4 5.7 15.8 5.7 4.9 15.8 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DivIC PF04977.15 CDJ63557.1 - 0.00025 20.7 1.8 0.00025 20.7 1.8 14.6 14 2 2 17 17 17 4 Septum formation initiator HOOK PF05622.12 CDJ63557.1 - 0.00086 17.6 13.9 0.00086 17.6 13.9 6.4 4 2 1 6 6 6 4 HOOK protein DUF2205 PF10224.9 CDJ63557.1 - 0.0018 18.2 1.1 0.0018 18.2 1.1 9.1 11 0 0 11 11 11 1 Short coiled-coil protein RILP PF11461.8 CDJ63557.1 - 0.033 14.4 23.8 0.07 13.4 0.5 6.8 7 0 0 7 7 7 0 Rab interacting lysosomal protein RTBV_P46 PF06216.11 CDJ63557.1 - 1.4 7.7 3.4 1.9 7.3 0.0 2.7 3 0 0 3 3 3 0 Rice tungro bacilliform virus P46 protein 2TM PF13239.6 CDJ63558.1 - 0.28 11.5 0.0 0.28 11.5 0.0 3.8 3 2 1 4 4 4 0 2TM domain Metallophos PF00149.28 CDJ63559.1 - 1.4e-05 25.7 0.0 0.0017 18.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ63559.1 - 0.0033 17.6 0.1 0.88 9.7 0.0 3.0 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_67N PF03648.14 CDJ63560.1 - 0.0064 16.8 0.5 0.017 15.4 0.5 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus PUB PF09409.10 CDJ63561.1 - 1.7e-24 85.6 0.0 4.9e-24 84.1 0.0 1.8 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 CDJ63561.1 - 9.4e-05 22.2 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Myosin_TH1 PF06017.13 CDJ63561.1 - 0.059 13.0 0.3 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding V_ATPase_I PF01496.19 CDJ63561.1 - 0.81 7.5 6.0 1 7.2 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCM3AP_GANP PF16769.5 CDJ63561.1 - 1.2 7.3 10.5 1.8 6.7 10.5 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP Borrelia_P83 PF05262.11 CDJ63561.1 - 4.8 5.5 11.3 6 5.2 11.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF5401 PF17380.2 CDJ63561.1 - 7.2 4.6 22.8 10 4.1 22.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) ArfGap PF01412.18 CDJ63562.1 - 2.5e-28 98.5 0.0 5.2e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Enkurin PF13864.6 CDJ63562.1 - 0.11 12.9 0.2 4.2 7.9 0.1 2.5 2 0 0 2 2 2 0 Calmodulin-binding Peptidase_M18 PF02127.15 CDJ63563.1 - 5e-133 444.0 0.0 7.5e-133 443.5 0.0 1.2 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CDJ63563.1 - 0.00043 19.4 0.0 0.0033 16.5 0.0 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Sec23_trunk PF04811.15 CDJ63564.1 - 5e-20 72.1 0.0 9.2e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CDJ63564.1 - 1.1e-16 60.5 0.4 3.6e-16 58.8 0.4 2.0 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CDJ63564.1 - 4e-10 39.6 5.1 8.4e-10 38.5 5.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CDJ63564.1 - 7.2e-08 33.1 0.0 4.3e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain WD40 PF00400.32 CDJ63565.1 - 5.9e-10 39.6 6.9 0.22 12.5 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat OmpH PF03938.14 CDJ63565.1 - 0.029 14.7 3.3 0.056 13.8 3.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Metal_resist PF13801.6 CDJ63565.1 - 0.15 12.3 8.1 0.4 10.9 8.1 1.6 1 0 0 1 1 1 0 Heavy-metal resistance DUF4376 PF14301.6 CDJ63565.1 - 0.17 12.3 0.8 0.41 11.0 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) UPF0242 PF06785.11 CDJ63565.1 - 0.32 11.1 2.0 0.54 10.3 2.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus POTRA_TamA_1 PF17243.2 CDJ63565.1 - 0.65 10.1 3.3 1.7 8.8 3.3 1.7 1 0 0 1 1 1 0 POTRA domain TamA domain 1 HECT PF00632.25 CDJ63566.1 - 4.5e-30 105.2 0.0 7.4e-27 94.6 0.0 2.2 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) AKAP7_NLS PF10469.9 CDJ63567.1 - 2.7e-37 128.7 0.1 4.4e-37 128.0 0.1 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 CDJ63567.1 - 0.00012 22.0 0.4 0.00022 21.2 0.4 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Inositol_P PF00459.25 CDJ63568.1 - 3.6e-16 59.5 0.5 1.7e-05 24.4 0.0 4.1 3 1 1 4 4 4 3 Inositol monophosphatase family Cons_hypoth95 PF03602.15 CDJ63569.1 - 1.4e-36 125.8 0.0 2.1e-35 122.0 0.0 2.3 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 CDJ63569.1 - 1.9e-07 31.0 0.0 3.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ63569.1 - 0.0012 19.5 0.0 0.0035 18.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDJ63569.1 - 0.0036 16.7 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CDJ63569.1 - 0.008 15.7 0.0 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain INTAP PF16617.5 CDJ63569.1 - 0.041 14.2 2.6 2.4 8.6 0.2 2.5 2 0 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region WGR PF05406.15 CDJ63569.1 - 0.17 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 WGR domain ABM PF03992.16 CDJ63570.1 - 0.0079 16.3 0.0 0.035 14.2 0.0 2.1 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase TnpV PF14198.6 CDJ63570.1 - 0.21 11.6 6.2 0.3 11.1 6.2 1.2 1 0 0 1 1 1 0 Transposon-encoded protein TnpV FTR PF01913.18 CDJ63570.1 - 0.23 11.4 0.8 0.49 10.3 0.3 1.9 1 1 1 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase TFIIA PF03153.13 CDJ63570.1 - 1.5 8.8 11.5 1.6 8.7 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5345 PF17280.2 CDJ63570.1 - 3.3 7.7 7.6 8 6.5 7.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Pyr_redox_2 PF07992.14 CDJ63572.1 - 8.2e-16 58.1 0.0 1.8e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIRS_C PF02769.22 CDJ63572.1 - 3.3e-15 56.5 3.1 7e-14 52.2 3.1 2.5 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 CDJ63572.1 - 3.7e-11 43.5 0.2 1.9e-10 41.2 0.2 2.3 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Pyr_redox PF00070.27 CDJ63572.1 - 3.6e-08 33.9 0.6 0.0035 17.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase UCR_TM PF02921.14 CDJ63572.1 - 0.013 16.0 0.0 0.04 14.4 0.0 1.9 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region Pyr_redox_3 PF13738.6 CDJ63572.1 - 0.044 13.0 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1635 PF07795.11 CDJ63572.1 - 0.4 10.5 3.7 4.2 7.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DHHC PF01529.20 CDJ63573.1 - 7e-11 42.4 9.2 1.4e-10 41.4 9.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Med27 PF11571.8 CDJ63573.1 - 1 9.8 5.6 6.3 7.2 1.3 3.4 3 0 0 3 3 3 0 Mediator complex subunit 27 RabGAP-TBC PF00566.18 CDJ63574.1 - 3.3e-42 144.6 0.0 7.2e-42 143.5 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box PF00646.33 CDJ63574.1 - 0.00089 19.1 1.0 0.0019 18.0 1.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDJ63574.1 - 0.038 13.9 1.2 0.095 12.6 1.2 1.6 1 0 0 1 1 1 0 F-box-like F-box_5 PF18511.1 CDJ63574.1 - 0.069 12.7 1.2 0.16 11.6 1.2 1.6 1 0 0 1 1 1 0 F-box DUF4810 PF16068.5 CDJ63575.1 - 0.091 13.3 1.6 0.18 12.4 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4810) GHMP_kinases_N PF00288.26 CDJ63575.1 - 0.2 11.9 1.3 1.2 9.5 0.2 2.6 2 0 0 2 2 2 0 GHMP kinases N terminal domain Rhodanese PF00581.20 CDJ63576.1 - 5.7e-17 62.2 0.0 0.0001 22.7 0.0 4.3 3 1 0 3 3 3 3 Rhodanese-like domain AAA_23 PF13476.6 CDJ63576.1 - 0.017 15.7 0.5 6.7 7.2 1.1 2.2 2 0 0 2 2 2 0 AAA domain Spc24 PF08286.11 CDJ63576.1 - 0.067 13.4 0.5 0.067 13.4 0.5 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SPT16 PF08644.11 CDJ63576.1 - 3.1 8.0 7.0 0.21 11.7 1.0 1.9 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) SNase PF00565.17 CDJ63577.1 - 2e-08 34.7 0.0 4.2e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Staphylococcal nuclease homologue RRM_1 PF00076.22 CDJ63578.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RT_RNaseH PF17917.1 CDJ63579.1 - 2.4e-29 101.7 0.0 4.8e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ63579.1 - 1.8e-28 98.5 0.1 3.3e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ63579.1 - 1.5e-20 73.7 0.0 2.6e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 CDJ63579.1 - 0.02 14.7 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like Asp_protease_2 PF13650.6 CDJ63580.1 - 6.8e-09 36.3 0.0 1.3e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ63580.1 - 2.9e-08 34.2 0.0 6.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ63580.1 - 6.5e-06 26.0 0.0 9.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CDJ63580.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.12 CDJ63580.1 - 0.049 13.4 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.10 CDJ63580.1 - 0.22 11.3 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 CDJ63581.1 - 0.0024 18.1 0.0 0.016 15.4 0.0 2.3 3 0 0 3 3 3 1 Retrotransposon gag protein DUF3425 PF11905.8 CDJ63581.1 - 0.025 14.5 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) RT_RNaseH_2 PF17919.1 CDJ63582.1 - 5.9e-27 93.6 0.1 9.2e-27 93.0 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ63582.1 - 3.2e-26 91.7 0.2 4.7e-26 91.1 0.2 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SUIM_assoc PF16619.5 CDJ63583.1 - 0.033 14.2 0.5 0.033 14.2 0.5 3.6 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 BAF1_ABF1 PF04684.13 CDJ63583.1 - 1.2 8.1 7.2 2 7.4 7.2 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ63583.1 - 1.6 7.4 4.6 2.3 6.9 4.6 1.4 1 0 0 1 1 1 0 Presenilin TMEM51 PF15345.6 CDJ63583.1 - 2.2 8.1 0.0 2.2 8.1 0.0 2.6 2 1 0 2 2 2 0 Transmembrane protein 51 SWI-SNF_Ssr4 PF08549.10 CDJ63583.1 - 2.3 6.7 13.1 3 6.4 13.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Hamartin PF04388.12 CDJ63583.1 - 2.5 6.6 4.7 3.5 6.2 4.7 1.1 1 0 0 1 1 1 0 Hamartin protein WBP-1 PF11669.8 CDJ63583.1 - 9.6 6.9 6.8 3.2 8.4 0.1 2.9 3 0 0 3 3 3 0 WW domain-binding protein 1 PAP1 PF08601.10 CDJ63584.1 - 2.7 7.6 8.8 3.8 7.1 8.8 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 SR-25 PF10500.9 CDJ63585.1 - 0.073 12.7 1.9 0.14 11.7 1.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FTCD_C PF04961.12 CDJ63585.1 - 0.21 11.4 6.9 0.42 10.3 6.9 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase IMUP PF15761.5 CDJ63585.1 - 1.9 9.2 11.4 0.44 11.3 6.5 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF1633 PF07794.11 CDJ63585.1 - 3.7 5.6 7.7 6 4.9 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) DUF4217 PF13959.6 CDJ63586.1 - 2.9e-13 49.8 0.2 8.1e-13 48.4 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 CDJ63586.1 - 0.0069 16.7 0.0 0.023 15.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3807 PF12720.7 CDJ63586.1 - 0.19 12.0 19.7 0.13 12.5 13.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) CCDC53 PF10152.9 CDJ63586.1 - 0.71 10.3 11.0 14 6.1 0.0 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RNA_pol_Rpc4 PF05132.14 CDJ63586.1 - 1 9.8 12.7 0.25 11.8 5.0 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Rtf2 PF04641.12 CDJ63586.1 - 1 8.6 15.4 1.1 8.6 9.1 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger AAA_11 PF13086.6 CDJ63586.1 - 1.5 8.5 12.1 1.1 9.0 8.0 2.0 2 0 0 2 2 2 0 AAA domain CPSF100_C PF13299.6 CDJ63586.1 - 2.5 8.3 11.5 3.2 7.9 5.7 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 CDJ63586.1 - 3.9 6.9 11.7 0.55 9.6 6.4 1.8 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 CDJ63586.1 - 4.2 6.3 10.6 2 7.4 7.5 1.8 2 0 0 2 2 2 0 Solute carrier family 12 TMEM214 PF10151.9 CDJ63586.1 - 8.9 4.6 10.3 13 4.0 10.3 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator SR-25 PF10500.9 CDJ63587.1 - 0.35 10.5 27.1 0.035 13.7 6.3 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ63589.1 - 0.0023 17.6 7.1 0.0028 17.3 7.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein C_GCAxxG_C_C PF09719.10 CDJ63589.1 - 0.017 15.4 2.9 0.024 14.9 2.9 1.2 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) PAP1 PF08601.10 CDJ63589.1 - 0.05 13.3 9.7 0.063 13.0 9.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 NPR3 PF03666.13 CDJ63589.1 - 0.32 9.7 7.1 0.35 9.6 7.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 CDJ63589.1 - 0.38 10.7 6.5 0.43 10.6 6.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4551 PF15087.6 CDJ63589.1 - 0.44 9.3 8.2 0.49 9.2 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TFIIA PF03153.13 CDJ63589.1 - 0.48 10.4 28.9 0.56 10.1 28.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4569 PF15133.6 CDJ63589.1 - 0.93 9.2 11.7 1.1 8.9 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Presenilin PF01080.17 CDJ63589.1 - 0.98 8.1 15.8 1.2 7.9 15.8 1.0 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 CDJ63589.1 - 1.4 8.2 15.6 1.6 8.1 15.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Zip PF02535.22 CDJ63589.1 - 2 7.5 4.6 2.3 7.4 4.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SMYLE_N PF18615.1 CDJ63589.1 - 2.1 7.8 11.8 2.5 7.6 11.8 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SLC12 PF03522.15 CDJ63589.1 - 3.2 6.7 9.6 3.7 6.5 9.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 ASD2 PF08687.11 CDJ63589.1 - 3.6 7.1 13.7 4.3 6.8 13.7 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 MSA-2c PF12238.8 CDJ63589.1 - 3.8 7.5 11.5 4.4 7.3 11.5 1.0 1 0 0 1 1 1 0 Merozoite surface antigen 2c Hid1 PF12722.7 CDJ63589.1 - 4 5.4 10.0 4.6 5.2 10.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CAML PF14963.6 CDJ63589.1 - 4.4 7.4 6.7 5.2 7.1 6.7 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand PIP5K PF01504.18 CDJ63589.1 - 5.3 6.2 6.0 6.3 5.9 6.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CCDC106 PF15794.5 CDJ63589.1 - 6.4 6.4 13.5 7.9 6.1 13.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RR_TM4-6 PF06459.12 CDJ63589.1 - 7.2 6.4 14.1 8.9 6.0 14.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 CDJ63589.1 - 7.7 6.4 17.4 9.7 6.1 17.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hydin_ADK PF17213.3 CDJ63589.1 - 8.1 6.7 17.8 9.6 6.4 17.8 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain GREB1 PF15782.5 CDJ63589.1 - 8.3 3.4 14.3 9.5 3.2 14.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Rtf2 PF04641.12 CDJ63589.1 - 8.8 5.6 13.6 12 5.2 13.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger AP2 PF00847.20 CDJ63590.1 - 1.6e-07 31.4 0.2 2.1e-07 31.1 0.2 1.1 1 0 0 1 1 1 1 AP2 domain IrmA PF18673.1 CDJ63590.1 - 0.033 14.3 0.3 0.037 14.2 0.3 1.1 1 0 0 1 1 1 0 interleukin receptor mimic protein A tRNA_anti-like PF12869.7 CDJ63591.1 - 0.36 10.4 6.2 1.7 8.2 2.7 2.4 2 0 0 2 2 2 0 tRNA_anti-like RskA PF10099.9 CDJ63591.1 - 7.1 6.9 20.9 1e+03 -0.1 20.9 2.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA BUD22 PF09073.10 CDJ63592.1 - 1.8e-05 24.3 0.3 1.8e-05 24.3 0.3 6.6 3 2 2 6 6 6 2 BUD22 SR-25 PF10500.9 CDJ63592.1 - 0.0024 17.5 13.8 0.0024 17.5 13.8 9.8 5 2 2 9 9 9 2 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ63592.1 - 0.0089 16.1 15.2 0.0089 16.1 15.2 13.4 9 4 0 9 9 9 1 Unstructured region C-term to UIM in Ataxin3 Mod_r PF07200.13 CDJ63594.1 - 0.11 12.6 0.4 0.11 12.6 0.4 2.2 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Dfp1_Him1_M PF08630.10 CDJ63594.1 - 2.6 8.3 5.5 8.8 6.6 2.2 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region SUIM_assoc PF16619.5 CDJ63595.1 - 0.008 16.2 4.5 0.008 16.2 4.5 19.6 10 4 4 14 14 14 5 Unstructured region C-term to UIM in Ataxin3 SMC_N PF02463.19 CDJ63596.1 - 1.4 8.3 15.9 3.1 7.2 15.9 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF4834 PF16118.5 CDJ63598.1 - 3.4e-05 24.7 0.6 3.4e-05 24.7 0.6 3.6 2 1 0 2 2 1 1 Domain of unknown function (DUF4834) UBA_e1_thiolCys PF10585.9 CDJ63598.1 - 0.0015 18.5 2.0 0.0015 18.5 2.0 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Ion_trans PF00520.31 CDJ63598.1 - 0.036 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein Nha1_C PF08619.10 CDJ63598.1 - 0.47 9.6 28.7 0.22 10.7 17.7 2.0 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus SH3-WW_linker PF16618.5 CDJ63598.1 - 1.8 9.0 28.2 0.22 12.0 18.3 2.1 2 0 0 2 2 2 0 Linker region between SH3 and WW domains on ARHGAP12 SID-1_RNA_chan PF13965.6 CDJ63598.1 - 2.5 6.4 10.9 0.44 8.9 0.0 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 CSG2 PF16965.5 CDJ63598.1 - 3.5 6.5 15.3 0.44 9.4 0.1 2.1 1 1 1 2 2 2 0 Ceramide synthase regulator FAM60A PF15396.6 CDJ63598.1 - 5 7.1 23.9 5.1 7.0 14.4 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DUF3729 PF12526.8 CDJ63598.1 - 5 8.7 11.8 8.3 8.0 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) DUF2514 PF10721.9 CDJ63598.1 - 5.2 7.1 27.6 2.2 8.3 17.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) TFIIA PF03153.13 CDJ63598.1 - 6 6.8 51.7 7 6.5 26.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tetraspanin PF00335.20 CDJ63598.1 - 7.2 6.3 7.4 3.6 7.2 5.2 1.7 1 1 1 2 2 2 0 Tetraspanin family V_ATPase_I PF01496.19 CDJ63598.1 - 7.8 4.3 17.9 1.7 6.5 0.6 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Roughex PF06020.11 CDJ63599.1 - 0.63 9.1 3.4 0.79 8.8 3.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein OAD_gamma PF04277.13 CDJ63599.1 - 0.81 10.3 0.0 0.81 10.3 0.0 3.9 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain NAD_binding_4 PF07993.12 CDJ63600.1 - 1.7e-12 47.1 0.1 1.2e-08 34.5 0.1 2.7 2 1 0 2 2 2 2 Male sterility protein Sterile PF03015.19 CDJ63600.1 - 2.5e-12 46.8 0.0 6.7e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 CDJ63600.1 - 2.8e-09 36.7 0.0 8.8e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase Otopetrin PF03189.13 CDJ63600.1 - 0.024 13.5 1.5 0.052 12.4 1.5 1.6 1 0 0 1 1 1 0 Otopetrin DUF2722 PF10846.8 CDJ63600.1 - 0.03 13.3 0.2 0.03 13.3 0.2 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2722) DUF2878 PF11086.8 CDJ63600.1 - 0.11 12.7 1.2 0.37 11.0 1.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2878) SID-1_RNA_chan PF13965.6 CDJ63600.1 - 0.11 10.9 9.3 0.22 9.9 9.3 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Adaptin_binding PF10199.9 CDJ63600.1 - 0.25 11.9 29.1 6.1 7.5 0.0 3.3 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 Tim54 PF11711.8 CDJ63600.1 - 2.2 7.0 20.8 0.069 11.9 9.9 2.9 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.13 CDJ63600.1 - 3.5 6.3 23.9 2.1 7.0 17.0 2.5 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 CAP PF00188.26 CDJ63601.1 - 0.088 13.6 0.3 0.15 12.9 0.3 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ63602.1 - 0.013 16.4 0.1 0.018 15.9 0.1 1.3 1 0 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ63603.1 - 0.0029 18.4 0.1 0.0043 17.9 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ63604.1 - 0.012 16.4 0.0 0.02 15.7 0.0 1.4 1 1 0 1 1 1 0 Cysteine-rich secretory protein family VRP1 PF03538.14 CDJ63605.1 - 0.038 13.4 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein CAP PF00188.26 CDJ63605.1 - 0.043 14.6 0.1 0.068 14.0 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family zf-CCHC PF00098.23 CDJ63606.1 - 1.6e-07 31.1 9.6 0.00099 19.1 0.9 2.5 2 0 0 2 2 2 2 Zinc knuckle Asp_protease_2 PF13650.6 CDJ63606.1 - 9.3e-06 26.2 0.0 2.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ63606.1 - 0.00014 22.4 0.0 0.00031 21.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 CDJ63606.1 - 0.00017 21.7 0.0 0.00041 20.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 CDJ63606.1 - 0.0015 18.3 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 CDJ63606.1 - 0.004 16.9 1.1 0.004 16.9 1.1 2.3 2 0 0 2 2 2 1 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CDJ63606.1 - 0.21 12.0 1.4 0.44 10.9 1.4 1.5 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_3 PF13917.6 CDJ63606.1 - 1.8 8.6 4.6 5.3 7.1 0.5 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ63606.1 - 2.2 8.1 10.5 1.1 9.1 2.0 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger MMR1 PF08505.10 CDJ63608.1 - 0.26 11.6 13.6 0.44 10.8 13.6 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Spc7 PF08317.11 CDJ63608.1 - 0.29 10.0 25.0 0.44 9.4 25.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CDJ63608.1 - 0.31 8.9 17.4 0.43 8.4 17.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 CDJ63608.1 - 0.65 8.8 10.6 1 8.2 10.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein MRP-S27 PF10037.9 CDJ63608.1 - 0.79 8.5 18.9 1 8.1 18.9 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 PAT1 PF09770.9 CDJ63608.1 - 0.87 7.8 24.6 1.1 7.5 24.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FapA PF03961.13 CDJ63608.1 - 1.1 7.8 9.8 1.7 7.1 9.8 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tweety PF04906.13 CDJ63608.1 - 1.3 7.6 21.6 0.025 13.3 1.0 2.8 2 1 0 2 2 2 0 Tweety EphA2_TM PF14575.6 CDJ63608.1 - 8.4 7.4 0.0 8.4 7.4 0.0 3.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SUIM_assoc PF16619.5 CDJ63609.1 - 0.0025 17.8 32.2 0.45 10.6 6.2 3.8 3 1 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 DUF5423 PF17461.2 CDJ63609.1 - 0.5 9.2 6.9 0.064 12.1 1.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5423) DUF4471 PF14740.6 CDJ63609.1 - 2.6 7.2 14.9 92 2.1 14.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4471) rve PF00665.26 CDJ63610.1 - 1.9e-14 53.9 0.0 2.4e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ63610.1 - 0.0023 17.7 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain MMR_HSR1 PF01926.23 CDJ63611.1 - 2e-15 56.9 0.0 5.2e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ63611.1 - 1.9e-07 31.2 0.0 0.00041 20.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CDJ63611.1 - 2.7e-05 23.7 0.0 4.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ63611.1 - 0.0016 18.5 2.5 0.008 16.3 0.1 2.4 2 0 0 2 2 2 1 Dynamin family Spt20 PF12090.8 CDJ63611.1 - 0.048 13.3 7.7 0.099 12.2 7.7 1.5 1 0 0 1 1 1 0 Spt20 family IHABP4_N PF16174.5 CDJ63611.1 - 0.21 12.2 11.7 0.92 10.1 2.9 2.5 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal MeaB PF03308.16 CDJ63611.1 - 0.37 9.7 3.4 1 8.3 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PGA2 PF07543.12 CDJ63611.1 - 0.82 9.6 10.2 4.8 7.2 1.5 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 AIG1 PF04548.16 CDJ63611.1 - 1.6 8.0 7.1 0.76 9.1 0.1 2.3 2 0 0 2 2 2 0 AIG1 family Activator_LAG-3 PF11498.8 CDJ63611.1 - 2.6 6.9 17.1 5.4 5.9 17.1 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ63611.1 - 9.5 6.1 19.3 0.039 14.0 3.2 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ63611.1 - 9.8 4.7 16.7 0.25 10.0 6.0 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Phlebovirus_NSM PF07246.11 CDJ63612.1 - 0.018 14.4 2.1 0.028 13.8 2.1 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ATG16 PF08614.11 CDJ63612.1 - 0.033 14.4 8.5 0.033 14.4 8.5 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) HMMR_N PF15905.5 CDJ63612.1 - 0.046 13.2 11.6 0.017 14.6 8.8 1.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 CDJ63612.1 - 0.078 13.5 17.4 0.049 14.1 12.4 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 CDJ63612.1 - 0.1 12.7 13.9 0.04 14.1 9.7 2.0 2 0 0 2 2 2 0 Tropomyosin like V_ATPase_I PF01496.19 CDJ63612.1 - 0.16 9.9 2.4 0.17 9.8 2.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CtIP_N PF10482.9 CDJ63612.1 - 0.2 11.7 10.9 0.1 12.6 6.8 2.1 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Cut12 PF11500.8 CDJ63612.1 - 0.23 11.4 4.6 0.14 12.1 2.2 1.8 1 1 0 1 1 1 0 Spindle pole body formation-associated protein Jnk-SapK_ap_N PF09744.9 CDJ63612.1 - 0.24 11.6 14.0 0.2 11.8 8.2 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Uso1_p115_C PF04871.13 CDJ63612.1 - 0.48 10.8 14.9 0.2 12.1 11.8 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Mod_r PF07200.13 CDJ63612.1 - 0.49 10.5 13.8 0.58 10.2 9.1 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HAUS-augmin3 PF14932.6 CDJ63612.1 - 0.69 9.4 13.6 0.27 10.8 8.6 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 CDJ63612.1 - 0.76 8.6 11.9 0.27 10.1 8.7 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 CDJ63612.1 - 0.82 9.7 15.2 2.3 8.3 11.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FapA PF03961.13 CDJ63612.1 - 0.88 8.1 5.5 0.35 9.4 3.1 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A MAS20 PF02064.15 CDJ63612.1 - 1.5 8.9 6.1 0.62 10.2 3.7 1.6 2 0 0 2 2 1 0 MAS20 protein import receptor DUF4094 PF13334.6 CDJ63612.1 - 1.6 9.2 6.2 1.8 9.1 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) UPF0242 PF06785.11 CDJ63612.1 - 1.7 8.7 11.4 1.7 8.7 8.9 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Occludin_ELL PF07303.13 CDJ63612.1 - 2.4 8.9 6.3 1.3 9.8 3.8 1.7 2 0 0 2 2 2 0 Occludin homology domain Sec34 PF04136.15 CDJ63612.1 - 2.4 8.0 8.7 0.73 9.7 6.0 1.5 2 0 0 2 2 1 0 Sec34-like family UPF0449 PF15136.6 CDJ63612.1 - 2.5 8.6 10.2 4.6 7.8 8.2 2.4 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 YabA PF06156.13 CDJ63612.1 - 3 8.5 8.0 1.8 9.2 5.3 2.0 2 0 0 2 2 2 0 Initiation control protein YabA DUF2203 PF09969.9 CDJ63612.1 - 3.5 8.4 6.2 3.4 8.4 3.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3450 PF11932.8 CDJ63612.1 - 3.9 6.7 14.8 3.3 6.9 12.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) COG6 PF06419.11 CDJ63612.1 - 4.1 5.5 12.1 0.48 8.6 7.3 1.7 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 GIT_CC PF16559.5 CDJ63612.1 - 4.3 7.3 11.8 2.3 8.1 4.6 2.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Phage_GP20 PF06810.11 CDJ63612.1 - 5.7 6.7 12.5 1.5 8.6 7.8 2.2 2 1 0 2 2 2 0 Phage minor structural protein GP20 ADIP PF11559.8 CDJ63612.1 - 8.6 6.4 18.4 2.4 8.2 14.1 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 CDJ63612.1 - 9.4 6.6 17.5 8.8 6.7 13.3 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 CDJ63613.1 - 1.8 7.7 6.8 4.8 6.3 6.8 1.7 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_60s PF00428.19 CDJ63613.1 - 8.8 7.0 81.8 0.81 10.3 8.2 5.5 4 1 1 5 5 5 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ63614.1 - 0.00046 20.5 57.0 0.0019 18.5 20.0 2.9 2 1 0 2 2 2 2 Anti-sigma-K factor rskA eIF-3_zeta PF05091.12 CDJ63614.1 - 0.78 8.6 27.7 0.7 8.8 20.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIG-U PF06728.13 CDJ63614.1 - 0.83 8.6 2.3 3.1 6.7 0.1 2.1 1 1 1 2 2 2 0 GPI transamidase subunit PIG-U VIR_N PF15912.5 CDJ63614.1 - 4.6 6.7 20.2 1 8.9 15.2 2.0 2 0 0 2 2 2 0 Virilizer, N-terminal Tic110 PF16940.5 CDJ63614.1 - 7.6 4.9 19.1 4.2 5.7 0.7 2.1 2 0 0 2 2 2 0 Chloroplast envelope transporter Acetyltransf_1 PF00583.25 CDJ63615.1 - 2e-05 24.8 0.0 3.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family RLL PF10036.9 CDJ63615.1 - 0.00028 20.8 4.8 0.00028 20.8 4.8 3.0 3 0 0 3 3 3 1 RNA transcription, translation and transport factor protein SfLAP PF11139.8 CDJ63615.1 - 0.0037 16.7 1.3 0.0037 16.7 1.3 2.0 2 1 0 2 2 2 1 Sap, sulfolipid-1-addressing protein Acetyltransf_7 PF13508.7 CDJ63615.1 - 0.013 15.9 0.1 0.031 14.7 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RskA PF10099.9 CDJ63615.1 - 0.04 14.2 77.4 0.12 12.7 8.7 4.7 2 1 1 3 3 3 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ63615.1 - 2.6 7.6 129.7 0.34 10.5 32.2 5.2 4 1 1 5 5 5 0 Nuclear RNA-splicing-associated protein Dynamin_N PF00350.23 CDJ63615.1 - 3 7.9 18.3 1.7 8.7 2.8 2.7 2 0 0 2 2 2 0 Dynamin family F-actin_cap_A PF01267.17 CDJ63616.1 - 4.9e-12 45.8 9.4 5.9e-10 39.0 6.0 3.3 1 1 1 2 2 2 2 F-actin capping protein alpha subunit RskA PF10099.9 CDJ63616.1 - 3e-05 24.4 22.4 0.00024 21.4 17.3 2.4 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ63616.1 - 0.00042 20.0 43.3 0.014 15.0 10.3 2.3 2 0 0 2 2 2 2 Spt20 family Semialdhyde_dhC PF02774.18 CDJ63616.1 - 0.027 14.5 1.6 0.027 14.5 1.6 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain SPX PF03105.19 CDJ63616.1 - 0.051 13.5 35.1 0.21 11.5 26.2 2.2 2 0 0 2 2 2 0 SPX domain DUF45 PF01863.17 CDJ63616.1 - 0.23 11.5 14.3 0.14 12.1 4.6 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF45 SARAF PF06682.12 CDJ63616.1 - 0.48 10.0 25.3 0.1 12.2 16.5 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Band_7 PF01145.25 CDJ63616.1 - 1 9.4 16.9 0.038 14.0 4.8 2.4 2 0 0 2 2 2 0 SPFH domain / Band 7 family Cwf_Cwc_15 PF04889.12 CDJ63616.1 - 2.2 8.0 26.0 1.8 8.2 12.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MCU PF04678.13 CDJ63616.1 - 3.2 7.8 9.3 9.5 6.3 3.1 2.5 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CAF-1_p150 PF11600.8 CDJ63616.1 - 3.2 7.4 26.8 0.15 11.7 15.7 2.8 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RNA_polI_A34 PF08208.11 CDJ63616.1 - 3.7 7.6 23.4 6.4 6.8 8.8 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 PIP5K PF01504.18 CDJ63617.1 - 6.2e-05 22.4 16.7 0.014 14.7 0.0 4.8 3 1 1 4 4 4 1 Phosphatidylinositol-4-phosphate 5-Kinase SR-25 PF10500.9 CDJ63617.1 - 0.00097 18.8 11.7 0.00097 18.8 11.7 6.6 5 2 1 6 6 6 3 Nuclear RNA-splicing-associated protein Adaptin_N PF01602.20 CDJ63618.1 - 9.6e-70 235.6 0.0 4.6e-54 183.9 0.6 2.5 1 1 1 2 2 2 2 Adaptin N terminal region Ribul_P_3_epim PF00834.19 CDJ63618.1 - 3.4e-30 104.9 0.0 2.8e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 Ribulose-phosphate 3 epimerase family Cnd1 PF12717.7 CDJ63618.1 - 9.4e-30 103.8 0.1 4.5e-13 49.5 0.0 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ63618.1 - 1.8e-05 25.1 0.4 0.02 15.3 0.0 4.4 4 0 0 4 4 4 1 HEAT repeats Sporozoite_P67 PF05642.11 CDJ63618.1 - 7.5e-05 21.0 3.5 7.5e-05 21.0 3.5 2.1 2 0 0 2 2 2 1 Sporozoite P67 surface antigen HEAT PF02985.22 CDJ63618.1 - 0.00084 19.4 1.5 0.12 12.7 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat SPX PF03105.19 CDJ63618.1 - 0.052 13.5 7.2 1.1 9.1 3.1 2.5 2 1 0 2 2 2 0 SPX domain Apt1 PF10351.9 CDJ63618.1 - 0.38 9.5 7.5 2.8 6.7 3.3 2.4 2 1 0 2 2 2 0 Golgi-body localisation protein domain DUF1645 PF07816.11 CDJ63618.1 - 0.64 10.6 20.3 0.12 12.9 3.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) Suf PF05843.14 CDJ63618.1 - 0.75 9.7 3.3 1.6 8.7 3.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Secretin_N_2 PF07655.13 CDJ63618.1 - 0.75 10.4 34.5 2.4 8.8 9.7 3.1 3 0 0 3 3 3 0 Secretin N-terminal domain Ecl1 PF12855.7 CDJ63618.1 - 1.1 10.4 21.2 0.71 11.0 5.1 3.0 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins DUF4667 PF15700.5 CDJ63618.1 - 1.7 8.7 25.6 0.19 11.8 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4667) MYT1 PF08474.11 CDJ63618.1 - 3.3 7.6 11.0 3.4 7.5 1.6 2.4 2 0 0 2 2 2 0 Myelin transcription factor 1 DUF2722 PF10846.8 CDJ63619.1 - 2e-05 23.7 4.0 2e-05 23.7 4.0 8.1 5 2 1 6 6 6 1 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ63619.1 - 0.0028 17.3 12.9 0.0028 17.3 12.9 8.3 4 2 3 7 7 7 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ63619.1 - 0.011 16.0 0.0 0.011 16.0 0.0 11.2 4 4 3 8 8 8 0 Anti-sigma-K factor rskA Hamartin PF04388.12 CDJ63621.1 - 4.8 5.7 50.5 7.1 5.2 50.5 1.1 1 0 0 1 1 1 0 Hamartin protein RskA PF10099.9 CDJ63623.1 - 0.53 10.6 0.0 0.53 10.6 0.0 4.9 3 2 0 3 3 3 0 Anti-sigma-K factor rskA Apt1 PF10351.9 CDJ63623.1 - 1.4 7.7 7.5 2.1 7.1 7.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain BAF1_ABF1 PF04684.13 CDJ63624.1 - 0.69 8.9 11.1 0.73 8.8 11.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SPX PF03105.19 CDJ63624.1 - 3.2 7.6 26.0 3.8 7.3 26.0 1.1 1 0 0 1 1 1 0 SPX domain PH_5 PF15405.6 CDJ63624.1 - 4.7 7.3 9.4 1.4 9.0 0.7 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Presenilin PF01080.17 CDJ63624.1 - 4.9 5.8 15.5 5.7 5.6 15.5 1.1 1 0 0 1 1 1 0 Presenilin Rep_fac-A_3 PF08661.11 CDJ63625.1 - 0.00031 21.1 0.0 0.00042 20.6 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Ribosomal_L1 PF00687.21 CDJ63626.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L1p/L10e family SUIM_assoc PF16619.5 CDJ63626.1 - 0.23 11.6 28.5 0.44 10.7 3.8 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 CCSAP PF15748.5 CDJ63626.1 - 2.9 8.0 6.3 4.5 7.4 6.3 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated His_Phos_1 PF00300.22 CDJ63627.1 - 1.5e-05 24.8 3.9 0.79 9.4 0.1 4.2 3 2 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) SR-25 PF10500.9 CDJ63627.1 - 0.0016 18.1 18.5 0.049 13.2 5.3 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ63627.1 - 0.028 14.5 22.9 0.048 13.7 1.8 3.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Velvet PF11754.8 CDJ63627.1 - 0.16 11.9 7.2 0.2 11.6 2.3 2.5 3 0 0 3 3 3 0 Velvet factor Macoilin PF09726.9 CDJ63627.1 - 2.1 6.8 8.5 1.8 7.0 0.6 2.2 2 0 0 2 2 2 0 Macoilin family Peptidase_S64 PF08192.11 CDJ63627.1 - 3 6.2 5.4 14 4.0 2.2 2.2 2 0 0 2 2 2 0 Peptidase family S64 Herpes_pp85 PF04637.12 CDJ63627.1 - 6.2 5.1 12.3 0.047 12.1 0.9 2.1 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) His_Phos_1 PF00300.22 CDJ63628.1 - 3.3e-12 46.5 0.0 1.5e-05 24.8 0.0 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 CDJ63629.1 - 0.00067 19.4 0.1 0.43 10.2 0.0 2.8 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) IBB PF01749.20 CDJ63629.1 - 0.22 12.0 3.9 0.17 12.3 1.0 2.1 2 0 0 2 2 2 0 Importin beta binding domain His_Phos_1 PF00300.22 CDJ63630.1 - 0.0051 16.5 0.1 0.16 11.6 0.0 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SPC22 PF04573.12 CDJ63631.1 - 4.1e-42 143.6 0.0 5.1e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit LSM PF01423.22 CDJ63632.1 - 7.7e-16 57.5 0.1 1.1e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDJ63632.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Hfq protein zf-C3HC4_2 PF13923.6 CDJ63633.1 - 0.044 13.6 0.8 0.094 12.6 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ63633.1 - 0.046 13.6 0.7 0.1 12.5 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rhabdo_ncap_2 PF03216.13 CDJ63634.1 - 3.2e-06 26.9 5.8 8.7 5.7 1.0 7.4 1 1 1 3 3 3 3 Rhabdovirus nucleoprotein Tau95 PF09734.9 CDJ63636.1 - 0.16 12.7 1.4 0.25 12.2 0.4 1.8 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain SOG2 PF10428.9 CDJ63636.1 - 1.2 8.2 23.0 1.6 7.8 23.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 CDJ63636.1 - 1.8 5.6 5.6 2.1 5.4 5.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hydin_ADK PF17213.3 CDJ63636.1 - 7.7 6.7 11.2 15 5.8 11.2 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain UCH PF00443.29 CDJ63637.1 - 6.5e-35 120.9 0.0 8.8e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CDJ63637.1 - 2.1e-06 27.3 0.0 9.6e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family UCH_1 PF13423.6 CDJ63637.1 - 0.0042 16.7 0.0 0.082 12.5 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TBK1_ULD PF18396.1 CDJ63637.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 CDJ63637.1 - 0.18 12.3 0.0 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF3391 PF11871.8 CDJ63637.1 - 2.8 8.5 0.0 2.8 8.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) DUF615 PF04751.14 CDJ63639.1 - 0.015 15.3 1.3 0.022 14.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) V-ATPase_C PF03223.15 CDJ63639.1 - 0.09 12.2 0.2 0.13 11.7 0.2 1.1 1 0 0 1 1 1 0 V-ATPase subunit C GTP_cyclohydroI PF01227.22 CDJ63639.1 - 0.76 9.2 2.7 0.45 9.9 0.7 1.6 2 0 0 2 2 2 0 GTP cyclohydrolase I KH_1 PF00013.29 CDJ63641.1 - 6.8e-05 22.6 0.4 0.00017 21.4 0.4 1.7 1 0 0 1 1 1 1 KH domain Mem_trans PF03547.18 CDJ63642.1 - 0.13 10.6 3.5 3.8 5.8 0.1 2.3 2 0 0 2 2 2 0 Membrane transport protein Peptidase_S64 PF08192.11 CDJ63642.1 - 1.3 7.4 11.6 1.9 6.9 11.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 SUIM_assoc PF16619.5 CDJ63643.1 - 0.0013 18.7 0.0 0.004 17.2 0.0 1.9 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ63643.1 - 0.052 13.2 6.7 0.097 12.3 6.7 1.4 1 0 0 1 1 1 0 Spt20 family TCP PF03634.13 CDJ63645.1 - 0.0014 19.2 3.2 0.0022 18.6 3.2 1.2 1 0 0 1 1 1 1 TCP family transcription factor RLL PF10036.9 CDJ63645.1 - 0.0028 17.5 5.6 0.0036 17.2 5.6 1.1 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein CCSAP PF15748.5 CDJ63645.1 - 0.0029 17.8 6.1 0.0046 17.2 6.1 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated Spt20 PF12090.8 CDJ63645.1 - 0.0035 17.0 14.6 0.0048 16.5 14.6 1.2 1 0 0 1 1 1 1 Spt20 family IMUP PF15761.5 CDJ63645.1 - 0.0088 16.7 1.8 0.0088 16.7 1.8 2.2 2 0 0 2 2 1 1 Immortalisation up-regulated protein Presenilin PF01080.17 CDJ63645.1 - 0.011 14.6 1.1 0.012 14.4 1.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ63645.1 - 0.012 16.6 1.9 0.012 16.6 1.9 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) DUF4647 PF15504.6 CDJ63645.1 - 0.017 14.3 5.0 0.024 13.7 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Velvet PF11754.8 CDJ63645.1 - 0.017 15.1 2.5 0.026 14.5 2.5 1.3 1 0 0 1 1 1 0 Velvet factor Tim54 PF11711.8 CDJ63645.1 - 0.023 13.5 0.6 0.029 13.2 0.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 CDJ63645.1 - 0.048 13.4 1.4 0.061 13.1 1.4 1.1 1 0 0 1 1 1 0 Connexin Nse4_C PF08743.10 CDJ63645.1 - 0.053 13.8 1.1 0.096 13.0 1.1 1.4 1 0 0 1 1 1 0 Nse4 C-terminal eIF-3_zeta PF05091.12 CDJ63645.1 - 0.063 12.3 3.3 0.076 12.0 3.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3464 PF11947.8 CDJ63645.1 - 0.072 12.8 1.6 0.13 12.0 1.6 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 UPF0239 PF06783.11 CDJ63645.1 - 0.093 12.9 2.9 0.19 11.9 2.9 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) RAP1 PF07218.11 CDJ63645.1 - 0.11 10.8 0.2 0.13 10.5 0.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ndc1_Nup PF09531.10 CDJ63645.1 - 0.11 11.2 3.7 0.14 10.8 3.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup OATP PF03137.20 CDJ63645.1 - 0.15 10.3 0.8 0.19 10.0 0.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EIIBC-GUT_N PF03612.14 CDJ63645.1 - 0.2 11.4 2.0 0.28 10.9 2.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus EOS1 PF12326.8 CDJ63645.1 - 0.21 11.5 0.7 0.27 11.1 0.7 1.1 1 0 0 1 1 1 0 N-glycosylation protein SR-25 PF10500.9 CDJ63645.1 - 0.32 10.6 25.3 0.21 11.2 1.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1645 PF07816.11 CDJ63645.1 - 0.37 11.4 11.5 3.4 8.2 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Conotoxin PF02950.17 CDJ63645.1 - 0.51 11.4 4.7 1 10.4 4.7 1.4 1 0 0 1 1 1 0 Conotoxin Med3 PF11593.8 CDJ63645.1 - 0.67 9.1 13.0 0.022 13.9 7.0 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DivIC PF04977.15 CDJ63645.1 - 1.1 9.1 11.3 2.6 7.9 11.3 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF5336 PF17270.2 CDJ63645.1 - 1.4 8.6 9.7 0.33 10.6 6.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5336) CNDH2_M PF16869.5 CDJ63645.1 - 1.4 9.7 6.3 0.47 11.2 1.1 2.1 2 0 0 2 2 2 0 PF16858 DUF2722 PF10846.8 CDJ63645.1 - 1.7 7.5 20.4 0.046 12.7 13.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) FlaG PF03646.15 CDJ63645.1 - 2.1 8.6 12.0 4.5 7.5 12.0 1.5 1 0 0 1 1 1 0 FlaG protein DUF775 PF05603.12 CDJ63645.1 - 2.2 7.8 9.3 0.2 11.2 4.9 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF775) TMEM208_SND2 PF05620.11 CDJ63645.1 - 3.3 7.4 5.6 5.3 6.8 5.6 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Activator_LAG-3 PF11498.8 CDJ63645.1 - 7.4 5.4 20.3 11 4.9 20.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CheD PF03975.13 CDJ63646.1 - 0.056 13.6 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 CheD chemotactic sensory transduction Utp14 PF04615.13 CDJ63646.1 - 0.17 10.4 37.8 0.27 9.7 37.8 1.3 1 0 0 1 1 1 0 Utp14 protein zf-CCCH PF00642.24 CDJ63647.1 - 5.3e-06 26.2 18.8 0.0014 18.4 0.8 3.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ63647.1 - 0.00022 21.2 15.4 0.069 13.2 1.1 3.5 3 0 0 3 3 3 2 Zinc finger domain Rick_17kDa_Anti PF05433.15 CDJ63647.1 - 0.1 12.5 14.3 12 5.8 3.7 3.6 1 1 1 2 2 2 0 Glycine zipper 2TM domain zf-CCCH_2 PF14608.6 CDJ63647.1 - 0.12 12.9 16.8 2.7 8.6 0.2 3.6 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CDJ63647.1 - 2.4 8.0 11.6 1.9 8.4 1.7 3.3 3 0 0 3 3 3 0 CCCH-type zinc finger DUF3995 PF13160.6 CDJ63648.1 - 0.00045 20.6 9.2 0.00045 20.6 9.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3995) RskA PF10099.9 CDJ63648.1 - 0.0018 18.6 17.9 0.0018 18.6 17.9 2.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA FAP PF07174.11 CDJ63648.1 - 0.012 15.0 14.8 0.015 14.8 14.8 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Spt20 PF12090.8 CDJ63648.1 - 7.1 6.2 19.2 9.8 5.7 19.2 1.2 1 0 0 1 1 1 0 Spt20 family DUF1345 PF07077.11 CDJ63649.1 - 1.6 8.4 5.8 0.47 10.1 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF3597 PF12200.8 CDJ63650.1 - 0.39 11.2 5.2 0.61 10.6 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF3138 PF11336.8 CDJ63650.1 - 0.68 8.5 5.5 0.82 8.2 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2057 PF09829.9 CDJ63650.1 - 1.2 9.3 4.2 1.7 8.8 4.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) SR-25 PF10500.9 CDJ63651.1 - 0.1 12.2 30.9 0.048 13.3 16.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ63651.1 - 0.13 12.2 8.0 0.16 11.9 8.0 1.0 1 0 0 1 1 1 0 SPX domain GREB1 PF15782.5 CDJ63651.1 - 3.9 4.5 9.2 0.34 8.0 5.0 1.3 1 1 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ63651.1 - 5 6.6 8.6 0.45 10.0 3.4 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ63652.1 - 0.0023 17.6 10.7 0.0023 17.6 10.7 3.9 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein Pyr_redox_2 PF07992.14 CDJ63653.1 - 3.1e-06 26.6 0.0 3.1e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ63653.1 - 0.0002 21.8 0.7 0.00038 21.0 0.7 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SPX PF03105.19 CDJ63653.1 - 0.0096 15.9 9.9 0.0096 15.9 9.9 1.1 1 0 0 1 1 1 1 SPX domain TMEM65 PF10507.9 CDJ63653.1 - 0.048 13.6 0.7 0.11 12.5 0.7 1.6 1 0 0 1 1 1 0 Transmembrane protein 65 Apt1 PF10351.9 CDJ63653.1 - 0.18 10.7 16.7 0.21 10.4 16.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tmemb_cc2 PF10267.9 CDJ63653.1 - 0.65 9.1 11.3 0.8 8.8 11.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.9 CDJ63653.1 - 0.8 8.2 23.9 0.94 8.0 23.9 1.1 1 0 0 1 1 1 0 Macoilin family DHHW PF14286.6 CDJ63653.1 - 6.5 6.0 8.6 8.6 5.6 8.6 1.1 1 0 0 1 1 1 0 DHHW protein Pap_E4 PF02711.14 CDJ63654.1 - 0.25 12.3 3.4 0.43 11.6 3.4 1.3 1 0 0 1 1 1 0 E4 protein DUF755 PF05501.11 CDJ63654.1 - 3 8.1 20.4 4 7.7 20.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Med15 PF09606.10 CDJ63656.1 - 0.003 16.4 12.4 0.003 16.4 12.4 6.4 4 1 2 6 6 6 3 ARC105 or Med15 subunit of Mediator complex non-fungal TIP49 PF06068.13 CDJ63657.1 - 5.2e-99 331.8 0.0 3e-94 316.1 0.0 2.3 1 1 1 2 2 2 2 TIP49 P-loop domain TIP49_C PF17856.1 CDJ63657.1 - 4.1e-23 81.3 1.0 8.5e-23 80.3 1.0 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain DUF2722 PF10846.8 CDJ63657.1 - 0.00056 19.0 4.8 0.00069 18.7 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ63657.1 - 0.0077 15.9 12.1 0.014 15.0 12.1 1.4 1 0 0 1 1 1 1 Spt20 family SR-25 PF10500.9 CDJ63657.1 - 0.0084 15.7 31.2 0.17 11.4 15.2 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein AAA_22 PF13401.6 CDJ63657.1 - 0.037 14.3 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Androgen_recep PF02166.16 CDJ63657.1 - 0.057 12.2 18.9 0.035 13.0 13.0 2.1 2 0 0 2 2 2 0 Androgen receptor eIF-3_zeta PF05091.12 CDJ63657.1 - 0.06 12.3 1.5 0.097 11.6 1.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ63657.1 - 0.068 11.9 1.8 0.091 11.5 1.8 1.2 1 0 0 1 1 1 0 Presenilin AAA PF00004.29 CDJ63657.1 - 0.094 13.1 0.1 1.2 9.5 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2681 PF10883.8 CDJ63657.1 - 0.11 12.9 11.0 6.5 7.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF755 PF05501.11 CDJ63657.1 - 0.13 12.5 32.0 1.2 9.5 17.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Neur_chan_memb PF02932.16 CDJ63657.1 - 0.15 12.1 0.6 0.27 11.3 0.3 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region AF-4 PF05110.13 CDJ63657.1 - 0.72 7.9 19.7 0.017 13.3 5.9 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein IMUP PF15761.5 CDJ63657.1 - 1.2 9.8 25.0 1.8 9.3 6.4 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein CDK2AP PF09806.9 CDJ63657.1 - 1.4 8.9 13.5 5.3 7.0 0.9 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Paf1 PF03985.13 CDJ63657.1 - 1.8 7.5 6.7 2.9 6.8 6.7 1.3 1 0 0 1 1 1 0 Paf1 Chorion_2 PF03964.15 CDJ63657.1 - 2.2 9.2 24.4 4.6 8.1 6.2 2.3 2 0 0 2 2 2 0 Chorion family 2 EBP50_C PF09007.11 CDJ63657.1 - 3 8.8 11.3 0.6 11.1 3.4 2.4 2 0 0 2 2 2 0 EBP50, C-terminal DUF4692 PF15763.5 CDJ63657.1 - 3.9 7.9 9.1 8.4 6.8 3.9 2.2 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Lin-8 PF03353.15 CDJ63657.1 - 4.3 6.8 12.4 0.44 10.1 7.2 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist ANAPC_CDC26 PF10471.9 CDJ63657.1 - 4.7 8.1 22.2 0.18 12.6 15.2 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Herpes_pp85 PF04637.12 CDJ63657.1 - 6.8 5.0 10.2 0.11 10.8 0.9 2.0 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF1635 PF07795.11 CDJ63657.1 - 8.3 6.2 11.8 1.7 8.4 6.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) SUIM_assoc PF16619.5 CDJ63660.1 - 0.082 13.0 0.1 0.082 13.0 0.1 9.0 7 2 1 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ63661.1 - 0.15 11.7 4.7 0.45 10.1 4.7 1.8 1 0 0 1 1 1 0 Spt20 family Cpn10 PF00166.21 CDJ63662.1 - 5.5e-36 122.5 0.1 7.6e-19 67.6 0.0 2.3 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit PreAtp-grasp PF18604.1 CDJ63662.1 - 0.049 13.3 0.5 5.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Pre ATP-grasp domain Cupin_3 PF05899.12 CDJ63662.1 - 0.067 12.9 0.4 0.7 9.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF861) SR-25 PF10500.9 CDJ63662.1 - 3.4 7.2 9.1 5.4 6.5 9.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Na_H_Exchanger PF00999.21 CDJ63663.1 - 4.6e-13 48.7 16.5 7.8e-13 48.0 10.7 2.4 1 1 1 2 2 2 1 Sodium/hydrogen exchanger family SPX PF03105.19 CDJ63663.1 - 0.00082 19.4 7.7 0.001 19.0 7.7 1.2 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 CDJ63663.1 - 0.0074 15.2 8.8 0.0091 14.9 8.8 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ63663.1 - 0.024 13.4 1.4 0.038 12.8 1.4 1.3 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CDJ63663.1 - 0.1 11.4 1.6 0.13 11.0 1.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PetL PF05115.14 CDJ63663.1 - 0.18 11.8 4.2 1.4 9.0 4.2 2.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) CRPA PF05745.11 CDJ63663.1 - 0.24 11.4 2.1 0.26 11.3 0.8 1.7 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Macoilin PF09726.9 CDJ63663.1 - 0.78 8.2 12.4 1.1 7.7 12.4 1.2 1 0 0 1 1 1 0 Macoilin family SpoIIIAH PF12685.7 CDJ63663.1 - 1.3 8.8 11.4 7.4 6.3 11.4 2.0 1 1 0 1 1 1 0 SpoIIIAH-like protein Menin PF05053.13 CDJ63663.1 - 1.4 7.2 4.7 2 6.7 4.7 1.2 1 0 0 1 1 1 0 Menin Ribosomal_60s PF00428.19 CDJ63663.1 - 3.7 8.2 9.7 10 6.8 9.7 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Flavi_DEAD PF07652.14 CDJ63665.1 - 0.088 12.8 0.9 0.25 11.3 0.3 2.0 1 1 1 2 2 2 0 Flavivirus DEAD domain Mt_ATP-synt_D PF05873.12 CDJ63665.1 - 1.4 8.8 12.2 0.081 12.8 4.8 2.4 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) PPTA PF01239.22 CDJ63666.1 - 9e-10 38.0 2.8 0.0076 16.0 0.1 3.7 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat DUF2722 PF10846.8 CDJ63666.1 - 0.00072 18.6 4.3 0.00072 18.6 4.3 4.1 3 2 1 4 4 4 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ63666.1 - 0.006 16.9 9.6 0.006 16.9 9.6 5.0 2 2 2 4 4 4 2 Anti-sigma-K factor rskA Caldesmon PF02029.15 CDJ63666.1 - 0.1 11.3 30.2 0.19 10.5 30.2 1.4 1 0 0 1 1 1 0 Caldesmon SpoIIP PF07454.11 CDJ63666.1 - 0.83 9.1 31.4 3.4 7.1 21.9 2.5 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 CDJ63666.1 - 1.2 9.2 36.5 1.4 9.0 22.3 2.8 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Gti1_Pac2 PF09729.9 CDJ63666.1 - 1.3 9.1 31.7 5.6 7.0 17.5 3.4 3 0 0 3 3 3 0 Gti1/Pac2 family PDCD2_C PF04194.13 CDJ63667.1 - 0.033 14.3 2.8 0.038 14.1 0.0 2.1 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain Aida_N PF08910.10 CDJ63667.1 - 0.09 13.2 3.3 4 7.9 0.2 2.6 2 0 0 2 2 2 0 Aida N-terminus DUF4614 PF15391.6 CDJ63667.1 - 0.15 12.0 16.2 0.019 15.0 9.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DUF1635 PF07795.11 CDJ63667.1 - 0.31 10.9 8.3 0.74 9.6 8.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Peptidase_S49_N PF08496.10 CDJ63667.1 - 0.42 10.7 5.6 0.87 9.6 5.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GREB1 PF15782.5 CDJ63667.1 - 4.4 4.3 9.2 0.037 11.2 1.4 1.4 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer SPX PF03105.19 CDJ63667.1 - 6.1 6.7 18.6 13 5.6 17.4 1.9 1 1 0 1 1 1 0 SPX domain Takusan PF04822.13 CDJ63668.1 - 0.027 14.3 1.5 0.057 13.3 0.0 2.0 2 0 0 2 2 2 0 Takusan XisH PF08814.10 CDJ63668.1 - 0.054 13.6 1.1 0.12 12.6 1.1 1.5 1 0 0 1 1 1 0 XisH protein MFS_1 PF07690.16 CDJ63669.1 - 6.5e-09 35.2 11.6 6.5e-09 35.2 11.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 CDJ63669.1 - 0.0041 15.5 8.2 0.09 11.0 0.0 3.1 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.16 CDJ63669.1 - 0.01 14.1 0.1 0.01 14.1 0.1 2.9 3 0 0 3 3 3 0 BT1 family MFS_2 PF13347.6 CDJ63669.1 - 0.031 12.9 5.9 0.022 13.4 2.2 2.2 2 0 0 2 2 2 0 MFS/sugar transport protein Pex2_Pex12 PF04757.14 CDJ63669.1 - 0.041 13.5 0.1 0.041 13.5 0.1 1.8 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region DUF4834 PF16118.5 CDJ63669.1 - 0.36 11.8 16.3 3.3 8.7 0.3 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) DUF4271 PF14093.6 CDJ63669.1 - 1.3 8.9 8.6 3.1 7.7 0.4 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4271) SARAF PF06682.12 CDJ63669.1 - 1.5 8.4 9.8 5.1 6.6 6.0 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis NST1 PF13945.6 CDJ63669.1 - 2.4 8.2 31.0 2.4 8.2 7.0 2.5 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF1980 PF09323.10 CDJ63669.1 - 3.7 7.4 8.1 17 5.2 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Connexin PF00029.19 CDJ63669.1 - 5.4 6.7 8.0 1.2e+02 2.3 0.0 3.1 3 0 0 3 3 3 0 Connexin Roughex PF06020.11 CDJ63669.1 - 8 5.4 8.9 15 4.6 8.9 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Ribosomal_L13 PF00572.18 CDJ63670.1 - 1.2e-18 67.5 0.1 1.1e-13 51.6 0.0 4.0 4 0 0 4 4 4 2 Ribosomal protein L13 Adeno_PV PF03910.13 CDJ63670.1 - 3.8 6.1 8.6 5.4 5.6 8.6 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV Tic110 PF16940.5 CDJ63670.1 - 9.5 4.6 6.1 13 4.1 6.1 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter NUMOD1 PF07453.13 CDJ63671.1 - 0.0096 16.2 1.2 3.5 8.0 0.2 2.6 2 0 0 2 2 2 2 NUMOD1 domain HTH_Mga PF08280.11 CDJ63671.1 - 0.037 14.1 0.1 0.58 10.2 0.0 2.1 1 1 1 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain BrkDBD PF09607.10 CDJ63671.1 - 0.06 13.1 0.8 2.1 8.2 0.2 2.3 1 1 1 2 2 2 0 Brinker DNA-binding domain Adenyl_cycl_N PF12633.7 CDJ63672.1 - 0.078 12.9 0.2 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase NT domain 2-Hacid_dh_C PF02826.19 CDJ63673.1 - 1.4e-30 105.9 0.0 1.7e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rod_cone_degen PF15201.6 CDJ63675.1 - 0.4 10.8 1.3 0.91 9.7 1.3 1.6 1 0 0 1 1 1 0 Progressive rod-cone degeneration DUF3597 PF12200.8 CDJ63675.1 - 8.1 7.0 17.9 0.18 12.3 4.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3597) RRM_1 PF00076.22 CDJ63676.1 - 1.3e-10 40.9 0.1 9.1e-06 25.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ63676.1 - 0.002 17.9 0.0 0.079 12.8 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif Presenilin PF01080.17 CDJ63676.1 - 0.018 13.8 5.6 0.024 13.4 5.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4523 PF15023.6 CDJ63676.1 - 0.024 14.5 1.9 0.041 13.7 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 CDJ63676.1 - 0.063 13.3 0.4 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RICTOR_N PF14664.6 CDJ63676.1 - 0.083 11.9 0.6 0.15 11.0 0.6 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF2828 PF11443.8 CDJ63676.1 - 0.096 10.8 5.0 0.12 10.4 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SARAF PF06682.12 CDJ63676.1 - 0.12 12.0 6.6 0.21 11.2 6.6 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis V_ATPase_I PF01496.19 CDJ63676.1 - 0.17 9.8 4.5 0.23 9.4 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 CDJ63676.1 - 0.62 8.7 9.5 0.86 8.2 9.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Renin_r PF07850.14 CDJ63676.1 - 0.7 10.5 2.0 0.86 10.2 0.1 1.9 2 0 0 2 2 2 0 Renin receptor-like protein ANAPC_CDC26 PF10471.9 CDJ63676.1 - 0.79 10.6 32.8 1.3 9.9 6.9 2.6 3 0 0 3 3 2 0 Anaphase-promoting complex APC subunit CDC26 Neur_chan_memb PF02932.16 CDJ63676.1 - 0.94 9.5 8.2 1.7 8.6 8.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4446 PF14584.6 CDJ63676.1 - 1.1 9.3 4.2 0.59 10.1 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF702 PF05142.12 CDJ63676.1 - 1.6 9.2 11.1 3.4 8.1 4.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF4820 PF16091.5 CDJ63676.1 - 2.4 7.5 9.4 3 7.1 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Hydin_ADK PF17213.3 CDJ63676.1 - 7.7 6.7 10.0 13 6.0 10.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Gly-zipper_YMGG PF13441.6 CDJ63676.1 - 8.4 6.2 18.1 2.6 7.9 0.3 3.8 2 1 0 2 2 2 0 YMGG-like Gly-zipper IPK PF03770.16 CDJ63677.1 - 2.3e-18 66.8 0.0 2.1e-17 63.6 0.0 2.2 1 1 0 1 1 1 1 Inositol polyphosphate kinase Hamartin PF04388.12 CDJ63677.1 - 8.4 4.9 9.9 13 4.3 9.9 1.3 1 0 0 1 1 1 0 Hamartin protein CBP_BcsG PF11658.8 CDJ63678.1 - 0.042 12.2 0.0 0.044 12.2 0.0 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG RRM_1 PF00076.22 CDJ63679.1 - 1.4e-08 34.4 0.0 3.1e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2367 PF10164.9 CDJ63679.1 - 0.057 13.9 2.6 0.37 11.3 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2367) TFIIA PF03153.13 CDJ63679.1 - 0.067 13.2 11.5 0.09 12.8 11.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ63679.1 - 1.8 8.1 10.8 2.5 7.7 10.8 1.2 1 0 0 1 1 1 0 Spt20 family SMYLE_N PF18615.1 CDJ63680.1 - 1.3 8.5 12.3 1.4 8.5 12.3 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain RskA PF10099.9 CDJ63680.1 - 1.6 9.0 20.9 1.8 8.9 20.9 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ63681.1 - 0.98 9.0 8.1 2 8.0 8.1 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ63681.1 - 7.9 6.3 17.7 8.3 6.2 17.7 1.1 1 0 0 1 1 1 0 SPX domain stn_TNFRSF12A PF12191.8 CDJ63682.1 - 0.035 14.3 2.1 0.06 13.6 2.1 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MFS_1 PF07690.16 CDJ63683.1 - 2.1e-17 63.1 31.4 2.1e-17 63.1 31.4 3.4 2 1 1 3 3 3 1 Major Facilitator Superfamily OATP PF03137.20 CDJ63683.1 - 2.6e-14 52.5 15.2 6.2e-14 51.2 11.5 3.3 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CDJ63683.1 - 0.00024 20.1 5.5 0.00024 20.1 5.5 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter RIFIN PF02009.16 CDJ63683.1 - 0.0025 17.8 10.3 0.0025 17.8 10.3 4.4 4 2 1 5 5 5 1 Rifin SUIM_assoc PF16619.5 CDJ63683.1 - 0.0077 16.3 63.4 0.02 15.0 7.3 5.8 5 0 0 5 5 5 3 Unstructured region C-term to UIM in Ataxin3 DDHD PF02862.17 CDJ63683.1 - 2.3 8.3 16.2 3.2 7.8 1.2 3.9 4 0 0 4 4 4 0 DDHD domain OSTbeta PF15048.6 CDJ63683.1 - 3 8.0 8.5 14 5.9 0.1 3.6 3 0 0 3 3 3 0 Organic solute transporter subunit beta protein EPL1 PF10513.9 CDJ63683.1 - 6.8 7.1 20.1 0.79 10.1 0.5 4.2 4 0 0 4 4 4 0 Enhancer of polycomb-like DUF2722 PF10846.8 CDJ63685.1 - 2.7e-05 23.3 0.8 2.7e-05 23.3 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RRM_1 PF00076.22 CDJ63685.1 - 3.1e-05 23.7 0.0 5.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FYTT PF07078.11 CDJ63685.1 - 3.6e-05 23.2 3.0 5.1e-05 22.8 3.0 1.2 1 0 0 1 1 1 1 Forty-two-three protein Cnd2 PF05786.14 CDJ63685.1 - 0.0027 16.4 0.3 0.0028 16.4 0.3 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF4770 PF15994.5 CDJ63685.1 - 0.017 15.4 6.4 0.023 14.9 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) ANAPC_CDC26 PF10471.9 CDJ63685.1 - 0.024 15.4 13.7 0.024 15.4 13.7 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CDJ63685.1 - 0.23 11.0 17.4 0.28 10.7 17.4 1.1 1 0 0 1 1 1 0 Spt20 family DUF1764 PF08576.10 CDJ63685.1 - 0.6 11.0 5.5 0.87 10.5 5.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Presenilin PF01080.17 CDJ63685.1 - 0.69 8.6 3.5 0.86 8.3 3.5 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ63685.1 - 3.2 7.7 15.9 4 7.3 15.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PKI PF02827.16 CDJ63685.1 - 3.9 7.7 7.8 6.4 7.1 7.8 1.3 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Androgen_recep PF02166.16 CDJ63685.1 - 4.5 6.0 16.2 6.1 5.6 16.2 1.1 1 0 0 1 1 1 0 Androgen receptor Roughex PF06020.11 CDJ63685.1 - 5.6 5.9 7.7 7.3 5.6 7.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF3138 PF11336.8 CDJ63685.1 - 6.7 5.2 6.3 9.3 4.7 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Trp_oprn_chp PF09534.10 CDJ63687.1 - 0.55 10.0 47.9 0.67 9.7 47.9 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Hamartin PF04388.12 CDJ63687.1 - 0.61 8.7 7.7 0.57 8.8 7.7 1.0 1 0 0 1 1 1 0 Hamartin protein Suf PF05843.14 CDJ63687.1 - 0.64 10.0 7.3 0.59 10.1 7.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ63687.1 - 3.5 7.5 29.9 3.9 7.4 29.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myc_N PF01056.18 CDJ63687.1 - 7.3 6.4 13.3 9.1 6.1 13.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region SR-25 PF10500.9 CDJ63688.1 - 0.00012 21.7 51.5 0.021 14.5 24.6 2.1 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CDJ63688.1 - 0.0037 17.8 26.7 0.0037 17.8 26.7 2.8 1 1 1 2 2 1 1 Dehydrin Pex14_N PF04695.13 CDJ63688.1 - 0.0056 17.3 32.4 0.18 12.5 9.6 2.1 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4614 PF15391.6 CDJ63688.1 - 0.26 11.3 39.6 0.3 11.1 16.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) SID-1_RNA_chan PF13965.6 CDJ63688.1 - 0.33 9.3 9.1 0.42 9.0 9.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LMBR1 PF04791.16 CDJ63688.1 - 0.63 8.9 10.2 0.77 8.6 10.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein GT87 PF09594.10 CDJ63688.1 - 3.1 7.5 19.2 0.44 10.2 1.6 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 87 DUF4813 PF16072.5 CDJ63688.1 - 3.8 7.1 27.6 4.4 6.9 8.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) BaxI_1 PF12811.7 CDJ63688.1 - 4.7 6.7 9.1 10 5.6 0.9 2.1 2 0 0 2 2 2 0 Bax inhibitor 1 like BSP_II PF05432.11 CDJ63688.1 - 4.9 6.8 20.8 6.7 6.3 20.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Draxin PF15550.6 CDJ63688.1 - 5 6.9 27.7 6.6 6.5 27.7 1.1 1 0 0 1 1 1 0 Draxin ASD2 PF08687.11 CDJ63688.1 - 7.5 6.0 30.6 0.83 9.2 13.0 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 SEEEED PF14797.6 CDJ63688.1 - 8.6 6.5 39.3 5.5 7.2 15.7 2.2 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex DUF4834 PF16118.5 CDJ63689.1 - 0.11 13.5 22.2 7.2 7.6 7.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF2828 PF11443.8 CDJ63689.1 - 0.16 10.0 9.7 0.19 9.8 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Nucleoside_tran PF01733.18 CDJ63689.1 - 0.76 9.1 0.0 0.76 9.1 0.0 2.8 2 1 0 2 2 2 0 Nucleoside transporter SR-25 PF10500.9 CDJ63689.1 - 4.1 6.9 21.6 0.063 12.9 5.2 3.0 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein AIF_C PF14721.6 CDJ63689.1 - 7.5 6.9 14.9 12 6.2 2.9 3.1 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SR-25 PF10500.9 CDJ63690.1 - 0.001 18.7 8.2 0.001 18.7 8.2 5.1 5 1 0 5 5 5 3 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ63691.1 - 8.9e-06 25.5 1.1 8.9e-06 25.5 1.1 3.1 3 0 0 3 3 3 1 Spt20 family SR-25 PF10500.9 CDJ63691.1 - 0.00092 18.9 15.8 0.00092 18.9 15.8 3.1 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ63691.1 - 0.0033 17.6 21.6 0.0033 17.6 21.6 2.2 2 0 0 2 2 2 1 Centriole, cilia and spindle-associated Dsh_C PF12316.8 CDJ63691.1 - 0.0042 17.5 2.3 0.0042 17.5 2.3 3.0 2 1 0 2 2 1 1 Segment polarity protein dishevelled (Dsh) C terminal DUF2722 PF10846.8 CDJ63691.1 - 0.012 14.6 0.6 0.012 14.6 0.6 3.4 3 1 0 3 3 2 0 Protein of unknown function (DUF2722) DUF4366 PF14283.6 CDJ63691.1 - 0.026 14.6 4.9 0.58 10.2 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) RskA PF10099.9 CDJ63691.1 - 0.037 14.3 26.4 0.26 11.6 11.1 3.9 1 1 2 3 3 3 0 Anti-sigma-K factor rskA LMBR1 PF04791.16 CDJ63691.1 - 0.056 12.4 3.7 0.091 11.7 3.7 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein SID-1_RNA_chan PF13965.6 CDJ63691.1 - 0.11 10.9 2.8 28 3.0 0.0 2.2 1 1 0 2 2 2 0 dsRNA-gated channel SID-1 EOS1 PF12326.8 CDJ63691.1 - 0.19 11.6 10.5 1.2 9.0 5.2 3.0 3 0 0 3 3 3 0 N-glycosylation protein DcuA_DcuB PF03605.14 CDJ63691.1 - 1 8.2 3.1 0.74 8.7 1.5 1.5 1 1 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF3824 PF12868.7 CDJ63691.1 - 1.1 10.0 26.1 0.041 14.6 12.3 2.6 3 0 0 3 3 2 0 Domain of unknwon function (DUF3824) PBP1_TM PF14812.6 CDJ63691.1 - 3.7 8.0 10.9 0.31 11.4 3.6 2.4 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peroxin-13_N PF04088.13 CDJ63691.1 - 5 7.4 12.1 2.5 8.4 3.6 3.1 3 0 0 3 3 3 0 Peroxin 13, N-terminal region STAC2_u1 PF16664.5 CDJ63691.1 - 6.3 7.3 29.1 0.29 11.6 1.1 3.2 3 0 0 3 3 3 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 PRC2_HTH_1 PF18118.1 CDJ63691.1 - 7.1 7.5 16.5 7.6 7.4 3.8 3.3 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain Plasmodium_Vir PF05795.11 CDJ63691.1 - 8.8 5.6 13.4 0.085 12.3 2.9 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein CitMHS PF03600.16 CDJ63692.1 - 0.21 10.8 8.0 0.25 10.5 8.0 1.1 1 0 0 1 1 1 0 Citrate transporter DUF503 PF04456.12 CDJ63692.1 - 3.2 7.7 5.5 22 5.0 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF503) GED PF02212.18 CDJ63693.1 - 1e-22 80.1 0.1 1e-22 80.1 0.1 2.2 4 0 0 4 4 4 1 Dynamin GTPase effector domain DUF4726 PF15855.5 CDJ63693.1 - 0.015 15.5 2.0 0.015 15.5 2.0 3.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4726) LPD22 PF18834.1 CDJ63693.1 - 0.063 13.5 6.7 3.8 7.8 3.6 2.8 1 1 1 2 2 2 0 Large polyvalent protein associated domain 22 Acetyltransf_6 PF13480.7 CDJ63693.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fic PF02661.18 CDJ63693.1 - 2.8 8.9 5.5 98 3.9 0.0 3.3 2 1 1 3 3 3 0 Fic/DOC family Totivirus_coat PF05518.11 CDJ63693.1 - 8.8 4.2 10.0 16 3.4 8.1 1.9 2 0 0 2 2 2 0 Totivirus coat protein zf-RanBP PF00641.18 CDJ63694.1 - 0.002 17.4 1.7 0.002 17.4 1.7 2.1 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Coilin_N PF15862.5 CDJ63694.1 - 0.059 13.2 21.5 0.098 12.5 0.0 5.2 4 1 1 5 5 5 0 Coilin N-terminus LMF1 PF06762.14 CDJ63696.1 - 1.3e-30 106.9 4.4 2.1e-13 50.2 0.0 3.2 2 1 1 3 3 3 3 Lipase maturation factor SR-25 PF10500.9 CDJ63696.1 - 3 7.4 11.0 4.5 6.8 11.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sm_multidrug_ex PF06695.11 CDJ63697.1 - 0.27 11.9 5.4 7 7.3 1.9 2.3 1 1 1 2 2 2 0 Putative small multi-drug export protein PIG-U PF06728.13 CDJ63697.1 - 0.48 9.4 5.5 0.44 9.5 3.9 1.6 1 1 1 2 2 2 0 GPI transamidase subunit PIG-U FHIPEP PF00771.20 CDJ63697.1 - 2.9 6.3 4.1 1.9 6.9 2.5 1.4 1 1 0 1 1 1 0 FHIPEP family Kelch_4 PF13418.6 CDJ63698.1 - 2.2e-11 43.6 0.3 0.0033 17.4 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ63698.1 - 5e-08 33.0 0.0 0.024 14.9 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 CDJ63698.1 - 2.3e-07 30.7 5.0 0.23 11.5 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 CDJ63698.1 - 4.8e-07 29.9 4.6 0.3 11.4 0.1 6.9 5 2 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ63698.1 - 7.5e-07 28.9 5.0 0.14 12.2 0.2 5.4 5 0 0 5 5 5 3 Kelch motif Ras PF00071.22 CDJ63698.1 - 0.00048 19.8 0.2 0.00077 19.1 0.2 1.3 1 0 0 1 1 1 1 Ras family Kelch_1 PF01344.25 CDJ63698.1 - 0.0012 18.4 0.2 0.18 11.4 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Roc PF08477.13 CDJ63698.1 - 0.0047 17.1 0.1 0.0047 17.1 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AP2 PF00847.20 CDJ63699.1 - 9.3e-07 29.0 1.4 9.3e-07 29.0 1.4 1.7 2 0 0 2 2 2 1 AP2 domain ETRAMP PF09716.10 CDJ63701.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.7 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) SLC12 PF03522.15 CDJ63701.1 - 3.1 6.7 40.8 2.9 6.8 20.9 2.2 2 0 0 2 2 2 0 Solute carrier family 12 GAGA_bind PF06217.12 CDJ63701.1 - 5.1 7.3 35.0 0.9 9.8 9.5 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Ribonuc_red_sm PF00268.21 CDJ63702.1 - 2.7e-21 76.3 2.1 2.7e-21 76.3 2.1 1.6 2 0 0 2 2 2 1 Ribonucleotide reductase, small chain cobW PF02492.19 CDJ63703.1 - 2.3e-21 76.2 15.9 5.8e-14 52.1 0.5 4.3 1 1 2 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain RAB3GAP2_N PF14655.6 CDJ63703.1 - 8.1e-05 22.1 1.0 8.1e-05 22.1 1.0 7.3 4 2 1 6 6 6 1 Rab3 GTPase-activating protein regulatory subunit N-terminus AAA_18 PF13238.6 CDJ63703.1 - 0.00077 20.0 8.2 0.0046 17.5 4.1 3.9 3 1 0 3 3 3 1 AAA domain SR-25 PF10500.9 CDJ63703.1 - 0.00078 19.1 11.4 0.00078 19.1 11.4 3.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ63703.1 - 0.01 15.4 5.4 0.01 15.4 5.4 7.0 3 2 2 5 5 5 0 Spt20 family MobB PF03205.14 CDJ63703.1 - 0.03 14.2 0.0 0.03 14.2 0.0 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CDJ63703.1 - 0.033 14.1 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 CDJ63703.1 - 0.036 14.0 0.2 0.088 12.7 0.2 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Lipase_GDSL_2 PF13472.6 CDJ63703.1 - 0.3 11.5 0.0 0.3 11.5 0.0 4.4 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF1779 PF08680.10 CDJ63703.1 - 2.7 8.1 0.0 2.7 8.1 0.0 4.8 4 2 1 5 5 5 0 TATA-box binding TPR_1 PF00515.28 CDJ63704.1 - 1.7e-19 68.7 3.8 3.9e-06 26.5 0.0 5.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ63704.1 - 2.1e-14 52.4 17.9 7e-05 22.7 0.1 6.7 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ63704.1 - 1.3e-11 44.0 5.8 1.8e-05 24.3 0.0 6.0 3 2 3 6 6 6 2 TPR repeat TPR_8 PF13181.6 CDJ63704.1 - 1.9e-08 33.9 1.4 0.0021 18.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ63704.1 - 1.4e-07 31.9 0.3 0.0002 21.8 0.3 5.6 6 0 0 6 6 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ63704.1 - 2.4e-06 27.6 13.2 4.1e-05 23.7 0.5 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ63704.1 - 2.7e-06 27.9 0.6 0.00019 22.0 0.4 7.8 7 2 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ63704.1 - 1.8e-05 24.7 12.3 0.025 15.0 0.1 6.0 6 1 1 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ63704.1 - 0.00078 19.6 5.1 1.7 9.0 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDJ63704.1 - 0.00095 19.4 19.1 0.17 12.2 6.1 4.8 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ63704.1 - 0.0052 16.7 9.8 0.46 10.6 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ63704.1 - 0.0094 16.7 0.0 0.22 12.4 0.0 8.9 6 2 3 9 9 7 3 Tetratricopeptide repeat SPATA3 PF15662.5 CDJ63704.1 - 6.9 7.3 0.0 6.9 7.3 0.0 4.2 3 1 0 3 3 2 0 Spermatogenesis-associated protein 3 family DUF4834 PF16118.5 CDJ63704.1 - 9.3 7.3 24.8 1.1 10.3 5.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) LTV PF04180.14 CDJ63705.1 - 0.0028 17.5 15.8 0.0028 17.5 15.8 2.3 2 0 0 2 2 2 1 Low temperature viability protein Caldesmon PF02029.15 CDJ63705.1 - 0.55 8.9 46.9 0.076 11.8 16.9 2.4 2 0 0 2 2 2 0 Caldesmon RSN1_7TM PF02714.15 CDJ63707.1 - 0.13 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate U1snRNP70_N PF12220.8 CDJ63708.1 - 3.4 8.4 19.2 3.4 8.4 7.1 3.1 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MCM PF00493.23 CDJ63710.1 - 4.3e-93 310.5 0.1 7.8e-93 309.7 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDJ63710.1 - 6.1e-27 94.0 0.2 1.7e-26 92.5 0.2 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDJ63710.1 - 2.1e-26 92.2 2.9 3.9e-26 91.3 2.9 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ63710.1 - 9.5e-07 28.4 0.1 5.1e-06 26.0 0.1 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_lid_7 PF17867.1 CDJ63710.1 - 0.0026 17.9 0.8 0.0065 16.7 0.8 1.6 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 CDJ63710.1 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ63710.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 CDJ63710.1 - 0.21 12.3 2.4 0.76 10.5 2.4 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal BAG PF02179.16 CDJ63710.1 - 0.88 10.0 5.9 0.25 11.8 0.3 2.8 3 0 0 3 3 3 0 BAG domain Peptidase_C1 PF00112.23 CDJ63712.1 - 1.8e-51 175.3 1.4 2.5e-51 174.9 1.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 CDJ63712.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide HemY_N PF07219.13 CDJ63713.1 - 0.03 14.5 0.6 0.082 13.1 0.6 1.7 1 0 0 1 1 1 0 HemY protein N-terminus RNB PF00773.19 CDJ63715.1 - 3.9e-26 92.2 0.1 2.9e-25 89.3 0.0 2.0 1 1 1 2 2 2 1 RNB domain OB_Dis3 PF17849.1 CDJ63715.1 - 3.1e-08 33.5 0.0 5.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CDJ63715.1 - 3.9e-06 26.9 0.0 0.0026 17.9 0.0 2.3 2 0 0 2 2 2 1 Cold shock domain SR-25 PF10500.9 CDJ63715.1 - 6.2e-05 22.7 43.1 0.01 15.5 16.4 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Rrp44_CSD1 PF17216.3 CDJ63715.1 - 0.00019 21.2 1.0 0.00049 19.8 0.0 2.1 2 0 0 2 2 2 1 Rrp44-like cold shock domain Apt1 PF10351.9 CDJ63715.1 - 0.00023 20.2 7.8 0.00025 20.0 7.8 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain SPX PF03105.19 CDJ63715.1 - 0.0023 17.9 8.1 0.0027 17.7 8.1 1.1 1 0 0 1 1 1 1 SPX domain DUF3446 PF11928.8 CDJ63715.1 - 0.0064 16.8 33.7 0.053 13.8 9.3 2.4 2 0 0 2 2 2 2 Early growth response N-terminal domain Vitellogenin_N PF01347.22 CDJ63715.1 - 0.046 12.1 0.0 0.81 8.0 0.0 2.0 1 1 0 1 1 1 0 Lipoprotein amino terminal region OB_RNB PF08206.11 CDJ63715.1 - 0.069 12.8 0.0 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease B OB domain Secretin_N_2 PF07655.13 CDJ63715.1 - 0.085 13.4 23.4 0.31 11.6 6.3 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain DNAPolymera_Pol PF11590.8 CDJ63715.1 - 0.2 11.5 0.4 13 5.7 0.0 2.6 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol Presenilin PF01080.17 CDJ63715.1 - 1.4 7.6 6.1 1.9 7.2 6.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 CDJ63715.1 - 1.6 7.5 10.7 2.1 7.1 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FlgH PF02107.16 CDJ63715.1 - 1.9 8.1 14.0 6.9 6.3 14.0 1.8 1 1 0 1 1 1 0 Flagellar L-ring protein SUZ PF12752.7 CDJ63715.1 - 2.1 9.1 21.3 0.35 11.7 5.0 2.5 2 0 0 2 2 2 0 SUZ domain Cwf_Cwc_15 PF04889.12 CDJ63715.1 - 2.4 7.8 10.8 3.9 7.2 10.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tmemb_9 PF05434.11 CDJ63715.1 - 4.7 7.1 4.9 6.3 6.7 0.0 2.3 1 1 1 2 2 2 0 TMEM9 DA1-like PF12315.8 CDJ63715.1 - 6.9 6.0 10.3 0.18 11.2 0.9 2.1 2 0 0 2 2 2 0 Protein DA1 BUD22 PF09073.10 CDJ63715.1 - 7.5 5.8 22.0 14 4.9 22.0 1.4 1 0 0 1 1 1 0 BUD22 GREB1 PF15782.5 CDJ63715.1 - 7.6 3.5 9.5 9.9 3.1 9.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sox_N PF12444.8 CDJ63715.1 - 8.4 7.6 24.1 16 6.7 7.7 2.3 2 0 0 2 2 2 0 Sox developmental protein N terminal CDK2AP PF09806.9 CDJ63715.1 - 9.6 6.2 15.1 1.5 8.8 2.6 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein TMEM223 PF14640.6 CDJ63716.1 - 0.046 13.9 2.5 0.057 13.6 2.5 1.0 1 0 0 1 1 1 0 Transmembrane protein 223 SARAF PF06682.12 CDJ63716.1 - 0.56 9.8 16.0 0.7 9.5 16.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis IF-2B PF01008.17 CDJ63716.1 - 1.3 8.2 7.3 1.5 7.9 7.3 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family Gti1_Pac2 PF09729.9 CDJ63716.1 - 1.5 8.9 12.3 2.3 8.3 12.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2126 PF09899.9 CDJ63716.1 - 6 4.8 13.2 7.4 4.5 13.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SLC12 PF03522.15 CDJ63716.1 - 6.2 5.7 19.1 7.1 5.5 19.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ63716.1 - 6.9 5.3 22.0 9.1 4.9 22.0 1.1 1 0 0 1 1 1 0 Presenilin COPI_assoc PF08507.10 CDJ63717.1 - 2.3e-05 24.5 2.0 4.3e-05 23.6 2.0 1.4 1 1 0 1 1 1 1 COPI associated protein Ribosomal_60s PF00428.19 CDJ63717.1 - 2.9 8.6 15.5 7.8 7.2 15.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Enkurin PF13864.6 CDJ63718.1 - 1.2e-20 73.7 0.6 1.2e-20 73.7 0.6 2.1 2 0 0 2 2 2 1 Calmodulin-binding DUF4366 PF14283.6 CDJ63719.1 - 4.5e-05 23.5 0.9 5.9e-05 23.2 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) HMG-CoA_red PF00368.18 CDJ63719.1 - 0.0083 15.2 0.9 0.011 14.7 0.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase DUF2681 PF10883.8 CDJ63719.1 - 0.036 14.5 0.8 0.036 14.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Pyocin_S PF06958.12 CDJ63719.1 - 0.038 14.5 1.9 0.055 14.0 1.9 1.2 1 0 0 1 1 1 0 S-type Pyocin Complex1_LYR PF05347.15 CDJ63719.1 - 0.14 12.3 3.8 0.78 9.8 0.1 2.9 2 1 1 3 3 3 0 Complex 1 protein (LYR family) DUF719 PF05334.13 CDJ63719.1 - 0.14 12.4 6.8 0.22 11.7 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Iron_permease PF04120.12 CDJ63719.1 - 0.14 11.9 3.8 0.19 11.5 3.8 1.2 1 0 0 1 1 1 0 Low affinity iron permease SKI PF01202.22 CDJ63719.1 - 0.31 11.1 4.1 0.27 11.4 2.6 1.5 1 1 1 2 2 2 0 Shikimate kinase Suf PF05843.14 CDJ63719.1 - 0.43 10.5 10.6 0.56 10.1 10.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Thg1C PF14413.6 CDJ63719.1 - 0.7 10.1 8.6 0.98 9.6 8.6 1.3 1 1 0 1 1 1 0 Thg1 C terminal domain ABC2_membrane_3 PF12698.7 CDJ63719.1 - 1 8.4 1.9 1 8.4 1.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Presenilin PF01080.17 CDJ63719.1 - 1.3 7.7 4.3 1.3 7.7 4.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4199 PF13858.6 CDJ63719.1 - 1.7 9.0 8.5 0.19 12.1 4.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) EIIBC-GUT_N PF03612.14 CDJ63719.1 - 2.9 7.6 7.2 3.4 7.4 6.7 1.4 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Vir_act_alpha_C PF10400.9 CDJ63719.1 - 8.9 7.1 11.5 0.59 10.9 5.2 2.1 2 1 0 2 2 2 0 Virulence activator alpha C-term tRNA-synt_1b PF00579.25 CDJ63720.1 - 3.3e-45 154.7 0.0 4.5e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Androgen_recep PF02166.16 CDJ63720.1 - 0.47 9.2 18.9 0.7 8.7 18.9 1.1 1 0 0 1 1 1 0 Androgen receptor SUIM_assoc PF16619.5 CDJ63721.1 - 0.16 12.0 11.5 0.41 10.7 11.5 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ63721.1 - 0.42 10.2 7.6 0.64 9.6 7.6 1.2 1 0 0 1 1 1 0 Spt20 family PP2C PF00481.21 CDJ63722.1 - 4.2e-19 69.2 1.4 5.3e-19 68.9 0.1 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C TFIIA PF03153.13 CDJ63722.1 - 0.011 15.7 18.5 0.013 15.5 18.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIE PF07228.12 CDJ63722.1 - 0.015 15.2 0.1 0.015 15.2 0.1 1.6 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) RNAse_A_bac PF18431.1 CDJ63722.1 - 0.54 11.2 4.5 2.4 9.1 4.4 1.9 1 1 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain MFS_1 PF07690.16 CDJ63723.1 - 4.8e-14 52.0 18.5 4.8e-14 52.0 18.5 5.7 4 2 1 5 5 5 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ63723.1 - 4e-11 42.4 6.8 1.1e-09 37.7 0.0 2.7 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 CDJ63723.1 - 2.2e-09 36.2 22.8 2.7e-06 26.0 3.2 5.6 3 2 2 5 5 5 2 Organic Anion Transporter Polypeptide (OATP) family DUF2722 PF10846.8 CDJ63723.1 - 4.5e-06 25.9 2.2 4.5e-06 25.9 2.2 8.6 8 1 0 8 8 8 2 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ63723.1 - 0.0021 18.7 6.2 0.0021 18.7 6.2 10.0 5 3 3 9 9 9 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 CDJ63723.1 - 0.011 16.7 3.2 0.011 16.7 3.2 8.5 9 1 0 9 9 9 0 Domain of unknown function (DUF4834) TMEM125 PF15109.6 CDJ63723.1 - 0.39 11.1 5.4 0.29 11.5 0.6 2.6 2 0 0 2 2 2 0 TMEM125 protein family EMP70 PF02990.16 CDJ63723.1 - 1.7 7.2 4.0 1.2 7.7 0.2 2.3 2 0 0 2 2 2 0 Endomembrane protein 70 RskA PF10099.9 CDJ63724.1 - 0.00011 22.5 1.3 0.00011 22.5 1.3 10.7 2 2 7 9 9 9 3 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ63725.1 - 0.00012 21.8 8.4 0.00012 21.8 8.4 5.9 5 1 1 6 6 6 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ63725.1 - 0.0013 17.0 18.5 0.0013 17.0 18.5 3.6 2 1 0 3 3 3 1 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.12 CDJ63725.1 - 0.0051 16.6 4.1 0.0051 16.6 4.1 3.2 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 CDJ63726.1 - 0.16 11.9 2.2 0.17 11.8 2.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Adap_comp_sub PF00928.21 CDJ63727.1 - 1.6e-47 162.2 0.0 2.5e-47 161.5 0.0 1.3 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Ribosomal_60s PF00428.19 CDJ63727.1 - 0.033 14.8 6.6 0.033 14.8 6.6 3.1 3 1 0 3 3 3 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ63728.1 - 0.0098 15.9 11.0 0.012 15.7 11.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ63728.1 - 0.14 12.8 28.3 0.3 11.7 6.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ63728.1 - 1.5 9.1 34.0 47 4.2 34.0 2.2 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Shadoo PF14999.6 CDJ63729.1 - 3.4 7.8 31.1 0.93 9.6 17.0 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective PCI PF01399.27 CDJ63730.1 - 3e-16 59.8 0.2 7.2e-15 55.4 0.0 2.6 3 0 0 3 3 3 1 PCI domain RPN5_C PF18098.1 CDJ63730.1 - 1.2e-11 44.4 0.7 3.7e-11 42.9 0.7 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain YfhO PF09586.10 CDJ63730.1 - 0.054 11.7 3.9 0.063 11.5 3.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO PIGA PF08288.12 CDJ63731.1 - 4e-38 129.9 3.7 9.6e-38 128.7 3.7 1.7 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CDJ63731.1 - 2.7e-27 95.9 4.5 4.9e-27 95.0 4.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CDJ63731.1 - 7.8e-24 84.1 0.0 1.2e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ63731.1 - 1.2e-21 77.5 0.0 2.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CDJ63731.1 - 1.6e-13 51.4 0.2 1.1e-12 48.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CDJ63731.1 - 5.8e-07 29.6 0.4 9.2e-07 29.0 0.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 CDJ63731.1 - 2.4e-05 24.6 0.0 5.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 CKS PF01111.19 CDJ63732.1 - 1.9e-21 76.1 0.0 4e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit cwf18 PF08315.12 CDJ63733.1 - 0.017 15.8 0.7 2.1 9.0 0.1 2.4 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor PP2C PF00481.21 CDJ63734.1 - 3.4e-37 128.5 0.0 4.5e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ63734.1 - 0.0019 17.8 0.0 0.0076 15.9 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ63734.1 - 0.021 14.8 0.0 0.18 11.7 0.0 2.3 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) YjgF_endoribonc PF14588.6 CDJ63734.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Peptidase_C2 PF00648.21 CDJ63735.1 - 3.2e-37 128.1 0.0 3.1e-36 124.9 0.0 2.3 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CDJ63735.1 - 3.1e-10 40.5 3.2 3.8e-05 24.0 0.1 4.2 3 1 1 4 4 4 3 Calpain large subunit, domain III Gpi16 PF04113.14 CDJ63736.1 - 1.2e-30 106.5 7.5 1.2e-21 76.9 6.2 3.1 2 1 0 2 2 2 2 Gpi16 subunit, GPI transamidase component DNA_pol3_tau_4 PF12168.8 CDJ63736.1 - 3.2 8.3 13.6 1.7 9.3 2.5 3.8 3 0 0 3 3 3 0 DNA polymerase III subunits tau domain IV DnaB-binding RAB3GAP2_N PF14655.6 CDJ63736.1 - 4.9 6.3 5.5 4.1 6.6 1.3 2.6 2 1 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Fib_alpha PF08702.10 CDJ63737.1 - 0.63 10.2 15.3 1.2 9.4 7.7 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HAUS5 PF14817.6 CDJ63737.1 - 1.3 7.7 44.5 2.4 6.8 39.7 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 MutS_V PF00488.21 CDJ63739.1 - 1.1e-76 257.1 1.8 3.2e-76 255.6 0.1 2.2 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CDJ63739.1 - 2.3e-16 60.6 0.7 2.3e-16 60.6 0.7 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CDJ63739.1 - 1.5e-05 25.3 1.9 2.1e-05 24.8 0.1 2.2 2 0 0 2 2 2 1 MutS family domain IV AAA_27 PF13514.6 CDJ63739.1 - 0.01 15.5 0.4 0.047 13.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CDJ63739.1 - 2.6 8.5 0.0 2.6 8.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain MMS19_N PF14500.6 CDJ63740.1 - 2.5e-28 99.4 0.0 2.5e-28 99.4 0.0 2.5 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF4064 PF13273.6 CDJ63740.1 - 0.13 12.5 3.2 4.2 7.7 0.1 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) RRM_1 PF00076.22 CDJ63741.1 - 1.2e-14 53.9 0.1 2.6e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CDJ63741.1 - 0.014 15.2 0.1 2.4 7.9 0.0 2.7 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain HCO3_cotransp PF00955.21 CDJ63741.1 - 0.23 10.2 0.4 0.37 9.6 0.4 1.2 1 0 0 1 1 1 0 HCO3- transporter family Pet20 PF08692.10 CDJ63741.1 - 0.47 11.2 3.1 0.46 11.2 0.3 2.0 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Sec62 PF03839.16 CDJ63741.1 - 1.3 8.4 11.4 0.32 10.5 4.7 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 PPL5 PF18168.1 CDJ63741.1 - 2.5 7.3 10.3 2.5 7.3 4.2 2.1 2 0 0 2 2 2 0 Prim-pol family 5 SpoIIP PF07454.11 CDJ63741.1 - 3.3 7.1 11.5 1.3 8.5 4.2 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4637 PF15470.6 CDJ63741.1 - 4.7 6.9 11.1 1.4 8.6 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) RPN2_C PF18004.1 CDJ63741.1 - 4.8 7.1 17.1 4.1 7.3 8.4 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CPSF100_C PF13299.6 CDJ63741.1 - 5.7 7.1 17.6 0.1 12.8 5.9 2.2 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 CDJ63741.1 - 8 6.7 18.1 9.4 6.5 1.1 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Connexin PF00029.19 CDJ63741.1 - 8.6 6.0 9.7 13 5.5 3.5 2.2 2 0 0 2 2 2 0 Connexin OKR_DC_1 PF01276.20 CDJ63743.1 - 5.6e-74 249.3 0.0 2.1e-53 181.6 0.0 2.2 1 1 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 CDJ63743.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1_C PF03711.15 CDJ63743.1 - 0.01 16.1 0.1 0.023 15.0 0.1 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain PrmA PF06325.13 CDJ63744.1 - 4.2e-11 42.8 0.2 8e-11 41.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CDJ63744.1 - 5.3e-09 36.7 0.1 1.9e-08 34.9 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ63744.1 - 2.2e-07 30.6 0.0 4.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CDJ63744.1 - 6.6e-07 29.2 0.0 3.2e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ63744.1 - 1.1e-06 28.6 0.1 3.3e-06 27.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ63744.1 - 6.7e-06 26.7 0.0 3.9e-05 24.2 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain CMAS PF02353.20 CDJ63744.1 - 0.00035 19.9 0.0 0.00067 19.0 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 CDJ63744.1 - 0.00049 20.1 0.0 0.00091 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ63744.1 - 0.0011 18.6 0.1 0.002 17.8 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 CDJ63744.1 - 0.0015 18.6 0.5 0.0052 16.8 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ63744.1 - 0.0016 17.8 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 CDJ63744.1 - 0.0031 16.5 0.2 0.01 14.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) PCMT PF01135.19 CDJ63744.1 - 0.0065 16.2 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 CDJ63744.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 CDJ63744.1 - 0.14 12.9 0.0 0.75 10.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 CDJ63744.1 - 0.16 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB zf-HIT PF04438.16 CDJ63745.1 - 8.3e-05 22.4 14.9 8.3e-05 22.4 14.9 1.8 2 0 0 2 2 2 1 HIT zinc finger Methyltransf_23 PF13489.6 CDJ63746.1 - 9.6e-15 54.8 0.0 1.8e-14 53.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ63746.1 - 5.6e-10 39.9 0.0 0.00015 22.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ63746.1 - 1.3e-07 32.2 0.0 0.0081 16.8 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ63746.1 - 5.1e-05 23.8 0.1 0.035 14.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ63746.1 - 0.0012 18.6 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 CDJ63746.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 CDJ63746.1 - 0.047 13.0 0.0 0.44 9.8 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_4 PF02390.17 CDJ63746.1 - 0.072 12.5 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase DUF3273 PF11677.8 CDJ63748.1 - 5.6e-99 330.8 6.1 6.4e-99 330.6 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Exo_endo_phos PF03372.23 CDJ63750.1 - 0.023 14.2 0.0 0.11 12.0 0.0 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family TPT PF03151.16 CDJ63751.1 - 8.5e-06 25.3 10.3 1.6e-05 24.4 10.3 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CDJ63751.1 - 0.00092 19.4 15.7 0.058 13.6 12.5 2.9 2 1 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 CDJ63751.1 - 0.061 13.4 3.0 0.12 12.4 3.0 1.5 1 0 0 1 1 1 0 Putative transmembrane family 234 TPR_17 PF13431.6 CDJ63752.1 - 0.015 15.6 0.1 0.048 14.0 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ63752.1 - 0.065 13.8 1.2 0.23 12.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SET PF00856.28 CDJ63752.1 - 0.11 12.9 0.0 0.38 11.1 0.0 2.1 2 1 0 2 2 2 0 SET domain Ank_4 PF13637.6 CDJ63753.1 - 1.9e-14 53.8 1.2 1.1e-08 35.4 0.5 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ63753.1 - 2.7e-13 50.3 0.8 2.6e-12 47.2 0.7 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ63753.1 - 3.6e-10 39.8 7.9 0.00042 20.6 2.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CDJ63753.1 - 6e-08 32.4 5.4 0.024 15.1 0.1 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CDJ63753.1 - 7.5e-08 32.5 1.0 3.7e-06 27.1 0.4 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) CRAL_TRIO_2 PF13716.6 CDJ63754.1 - 4.9e-14 52.7 0.1 7.9e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.21 CDJ63754.1 - 9e-07 29.0 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Macro domain Abhydrolase_1 PF00561.20 CDJ63755.1 - 9.7e-05 22.1 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ63755.1 - 0.00016 21.1 0.2 0.071 12.4 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ63755.1 - 0.00062 20.4 1.4 0.0014 19.3 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CDJ63755.1 - 0.0011 18.8 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Lipase (class 3) Thioesterase PF00975.20 CDJ63755.1 - 0.025 14.7 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain FSH1 PF03959.13 CDJ63755.1 - 0.073 12.7 0.0 0.55 9.9 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Shugoshin_N PF07558.11 CDJ63756.1 - 0.048 13.5 2.0 0.61 10.0 0.6 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region VPS11_C PF12451.8 CDJ63756.1 - 7 7.0 6.2 0.69 10.2 0.5 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Pkinase PF00069.25 CDJ63757.1 - 2.2e-57 194.4 6.2 1.3e-35 123.0 0.1 3.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63757.1 - 3.8e-26 91.9 9.8 2.4e-25 89.3 0.0 3.4 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ63757.1 - 0.005 15.8 0.3 0.005 15.8 0.3 3.9 4 0 0 4 4 4 1 Haspin like kinase domain PP2C PF00481.21 CDJ63758.1 - 2.1e-31 109.5 0.0 1.1e-30 107.2 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C FAST_1 PF06743.15 CDJ63759.1 - 0.0023 17.9 2.3 0.16 11.9 1.2 3.4 3 0 0 3 3 3 2 FAST kinase-like protein, subdomain 1 RRM_1 PF00076.22 CDJ63761.1 - 8.7e-13 47.9 0.0 1.8e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 CDJ63762.1 - 6.8e-08 32.9 12.5 8.1e-08 32.7 12.5 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SRP-alpha_N PF04086.13 CDJ63762.1 - 0.37 10.7 15.7 0.47 10.3 15.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BSP_II PF05432.11 CDJ63762.1 - 1.3 8.6 18.4 2.2 7.9 18.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) R3H-assoc PF13902.6 CDJ63763.1 - 0.00022 21.6 0.1 0.00022 21.6 0.1 3.9 6 0 0 6 6 6 1 R3H-associated N-terminal domain FliD_N PF02465.18 CDJ63763.1 - 0.014 16.0 3.7 0.014 16.0 3.7 3.1 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Menin PF05053.13 CDJ63764.1 - 0.86 7.9 5.9 1.1 7.5 5.9 1.0 1 0 0 1 1 1 0 Menin AP3D1 PF06375.11 CDJ63765.1 - 0.0011 19.2 17.6 0.0016 18.7 17.6 1.3 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 SR-25 PF10500.9 CDJ63765.1 - 0.02 14.5 23.4 0.026 14.1 23.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vfa1 PF08432.10 CDJ63765.1 - 0.027 14.8 14.9 0.034 14.5 14.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CRA PF06589.11 CDJ63765.1 - 0.15 12.2 20.0 0.22 11.6 20.0 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Presenilin PF01080.17 CDJ63765.1 - 0.31 9.7 1.8 0.33 9.7 1.8 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 CDJ63765.1 - 0.48 10.1 6.3 0.56 9.9 6.3 1.1 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 CDJ63765.1 - 0.73 9.5 3.2 1.1 9.0 3.2 1.2 1 0 0 1 1 1 0 FAM176 family Paramyxo_ncap PF00973.19 CDJ63765.1 - 0.84 8.5 4.4 0.92 8.3 4.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RNA_polI_A34 PF08208.11 CDJ63765.1 - 0.89 9.6 24.5 1.1 9.3 24.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 CDJ63765.1 - 1.3 7.2 8.6 1.4 7.1 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Eapp_C PF10238.9 CDJ63765.1 - 2.3 8.3 8.2 3.1 7.9 8.2 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Ureide_permease PF07168.11 CDJ63765.1 - 3.1 6.5 4.6 3.7 6.2 4.6 1.1 1 0 0 1 1 1 0 Ureide permease PPL5 PF18168.1 CDJ63765.1 - 4.1 6.6 9.8 5.8 6.1 9.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Zip PF02535.22 CDJ63765.1 - 4.3 6.5 4.0 6.4 5.9 4.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TMEM214 PF10151.9 CDJ63765.1 - 4.8 5.5 13.1 5.7 5.3 13.1 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator BRF1 PF07741.13 CDJ63765.1 - 6 7.3 23.8 10 6.5 23.7 1.4 1 1 0 1 1 1 0 Brf1-like TBP-binding domain SOUL PF04832.12 CDJ63766.1 - 0.027 14.7 0.2 0.053 13.7 0.2 1.5 2 0 0 2 2 2 0 SOUL heme-binding protein Striatin PF08232.12 CDJ63766.1 - 0.11 13.1 6.8 0.17 12.5 6.8 1.2 1 0 0 1 1 1 0 Striatin family SR-25 PF10500.9 CDJ63766.1 - 0.19 11.3 10.1 0.28 10.8 10.1 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein EMC3_TMCO1 PF01956.16 CDJ63766.1 - 0.77 9.5 2.6 0.98 9.1 2.6 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PsbM PF05151.12 CDJ63769.1 - 0.053 13.3 1.3 0.11 12.3 1.3 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) CEP63 PF17045.5 CDJ63770.1 - 0.012 15.6 2.2 0.018 15.0 2.2 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Mog1 PF04603.12 CDJ63770.1 - 0.19 12.1 0.6 3.7 7.9 0.6 2.2 1 1 0 1 1 1 0 Ran-interacting Mog1 protein LapA_dom PF06305.11 CDJ63770.1 - 0.89 9.4 4.8 4.4 7.2 0.8 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SpoIIP PF07454.11 CDJ63772.1 - 0.1 12.1 1.5 0.15 11.5 1.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Lin-8 PF03353.15 CDJ63772.1 - 0.2 11.2 6.7 15 5.0 10.6 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TRAP_alpha PF03896.16 CDJ63772.1 - 0.5 9.5 2.6 0.86 8.7 2.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 CDJ63772.1 - 0.61 8.8 3.4 0.95 8.2 3.4 1.2 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 CDJ63772.1 - 0.73 8.6 5.5 1.3 7.7 5.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoVR PF04293.13 CDJ63772.1 - 2.1 7.0 5.6 3.2 6.4 5.6 1.2 1 0 0 1 1 1 0 SpoVR like protein DUF4589 PF15252.6 CDJ63772.1 - 2.3 8.2 7.5 6.1 6.8 6.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4589) TCP PF03634.13 CDJ63772.1 - 3.3 8.3 10.2 0.17 12.4 2.3 2.4 2 0 0 2 2 2 0 TCP family transcription factor Spt20 PF12090.8 CDJ63772.1 - 4.1 6.9 30.4 1.4 8.5 22.1 2.5 2 0 0 2 2 2 0 Spt20 family Cas_Csy2 PF09614.10 CDJ63773.1 - 0.16 11.3 3.3 0.24 10.7 3.3 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) Ribosomal_60s PF00428.19 CDJ63773.1 - 0.29 11.8 24.0 2 9.1 5.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein RAP PF08373.10 CDJ63774.1 - 0.0014 18.7 1.7 0.0019 18.3 0.0 2.1 2 0 0 2 2 2 1 RAP domain Ferlin_C PF16165.5 CDJ63774.1 - 0.026 14.5 4.2 0.57 10.1 0.4 2.6 2 0 0 2 2 2 0 Ferlin C-terminus Endostatin PF06482.11 CDJ63774.1 - 0.099 12.1 25.8 0.55 9.6 7.0 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Tim54 PF11711.8 CDJ63774.1 - 0.2 10.4 17.9 0.99 8.1 4.5 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 PA26 PF04636.13 CDJ63774.1 - 0.31 9.9 22.8 0.022 13.7 6.5 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) DUF4746 PF15928.5 CDJ63774.1 - 0.74 9.2 18.2 0.53 9.6 4.7 3.0 2 1 1 3 3 2 0 Domain of unknown function (DUF4746) Neur_chan_memb PF02932.16 CDJ63774.1 - 0.97 9.4 20.2 0.98 9.4 5.0 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ63774.1 - 1.2 7.8 36.7 0.088 11.6 10.2 2.3 2 0 0 2 2 2 0 Presenilin Hid1 PF12722.7 CDJ63774.1 - 1.9 6.5 28.6 1.2 7.2 11.2 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein PAP1 PF08601.10 CDJ63774.1 - 2 8.1 29.1 0.064 13.0 11.5 2.3 2 0 0 2 2 2 0 Transcription factor PAP1 CNDH2_C PF16858.5 CDJ63774.1 - 2.2 8.1 29.4 0.61 9.9 6.9 2.4 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CAF1 PF04857.20 CDJ63774.1 - 2.5 7.2 15.0 1.8 7.7 0.4 2.3 2 0 0 2 2 2 0 CAF1 family ribonuclease Apt1 PF10351.9 CDJ63774.1 - 3.3 6.4 27.0 1.8 7.3 1.4 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Hydin_ADK PF17213.3 CDJ63775.1 - 2.8 8.2 21.8 3.2 8.0 21.8 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain eIF-3_zeta PF05091.12 CDJ63775.1 - 4.6 6.1 25.8 5.4 5.9 25.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4569 PF15133.6 CDJ63775.1 - 5.2 6.7 24.2 6.2 6.5 24.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Spt20 PF12090.8 CDJ63777.1 - 0.00039 20.1 6.2 0.00039 20.1 6.2 2.0 2 0 0 2 2 2 2 Spt20 family MID_MedPIWI PF18296.1 CDJ63777.1 - 0.063 13.1 11.7 0.077 12.8 11.7 1.1 1 0 0 1 1 1 0 MID domain of medPIWI TMEM107 PF14995.6 CDJ63777.1 - 0.11 12.9 0.4 0.26 11.7 0.0 1.8 2 1 0 2 2 2 0 Transmembrane protein AF-4 PF05110.13 CDJ63777.1 - 0.35 8.9 20.2 0.5 8.4 20.2 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF1645 PF07816.11 CDJ63777.1 - 0.37 11.3 11.0 0.44 11.1 8.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF4457 PF14652.6 CDJ63777.1 - 3.8 6.7 6.0 0.64 9.2 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4457) SUZ PF12752.7 CDJ63777.1 - 5.1 7.9 15.6 6 7.7 12.3 2.6 2 1 0 2 2 2 0 SUZ domain DEAD PF00270.29 CDJ63778.1 - 4.8e-26 91.6 4.5 1.3e-25 90.2 0.0 3.4 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ63778.1 - 2.1e-23 82.8 0.1 2.1e-23 82.8 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ63778.1 - 0.12 12.6 0.1 0.12 12.6 0.1 5.0 4 2 0 4 4 4 0 AAA domain FAM60A PF15396.6 CDJ63778.1 - 6 6.8 28.3 2 8.3 4.7 3.7 3 0 0 3 3 3 0 Protein Family FAM60A Peptidase_M24 PF00557.24 CDJ63779.1 - 1.1e-14 54.6 10.4 1e-10 41.7 2.4 2.9 2 1 1 3 3 3 2 Metallopeptidase family M24 DUF2722 PF10846.8 CDJ63779.1 - 0.00057 19.0 1.4 0.00081 18.5 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ63779.1 - 0.00076 19.6 7.2 0.0012 19.0 3.2 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ63779.1 - 0.0033 17.1 6.7 0.0033 17.1 6.7 1.6 2 0 0 2 2 2 1 Spt20 family Med15 PF09606.10 CDJ63779.1 - 0.81 8.3 14.6 0.015 14.0 6.9 1.8 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Phostensin_N PF13916.6 CDJ63779.1 - 1.8 9.0 6.5 1.1 9.7 3.1 2.3 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Porin_4 PF13609.6 CDJ63779.1 - 4.2 7.0 0.0 4.2 7.0 0.0 3.5 4 0 0 4 4 4 0 Gram-negative porin CCDC24 PF15669.5 CDJ63780.1 - 0.0024 17.8 10.9 0.0032 17.4 10.9 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family DUF755 PF05501.11 CDJ63780.1 - 0.0034 17.7 27.6 0.0046 17.2 27.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) GvpL_GvpF PF06386.11 CDJ63780.1 - 0.0056 16.7 1.0 0.0068 16.4 1.0 1.1 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF PAP1 PF08601.10 CDJ63780.1 - 0.01 15.6 10.0 0.012 15.3 10.0 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 DNA_primase_lrg PF04104.14 CDJ63780.1 - 0.034 13.5 0.3 0.044 13.2 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit MID_MedPIWI PF18296.1 CDJ63780.1 - 0.034 13.9 6.1 0.039 13.7 6.1 1.1 1 0 0 1 1 1 0 MID domain of medPIWI BTG PF07742.12 CDJ63780.1 - 0.05 13.5 0.8 0.08 12.8 0.8 1.4 1 0 0 1 1 1 0 BTG family TFIIA PF03153.13 CDJ63780.1 - 0.087 12.8 11.5 0.1 12.6 11.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TRP PF06011.12 CDJ63780.1 - 0.12 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel GREB1 PF15782.5 CDJ63780.1 - 0.2 8.7 8.6 0.24 8.5 8.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AF-4 PF05110.13 CDJ63780.1 - 0.21 9.6 20.2 0.26 9.4 20.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF1645 PF07816.11 CDJ63780.1 - 1 9.9 15.3 1.3 9.5 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Herpes_pp85 PF04637.12 CDJ63780.1 - 1.1 7.6 10.5 1.5 7.2 10.5 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SPX PF03105.19 CDJ63780.1 - 1.5 8.6 11.5 1.9 8.4 11.5 1.1 1 0 0 1 1 1 0 SPX domain Spt20 PF12090.8 CDJ63780.1 - 3 7.4 13.7 4.2 6.9 13.7 1.2 1 0 0 1 1 1 0 Spt20 family Lin-8 PF03353.15 CDJ63780.1 - 6.7 6.2 10.0 8.9 5.8 10.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pepsin-I3 PF06394.13 CDJ63780.1 - 8.1 6.7 8.2 14 5.9 8.2 1.4 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Miga PF10265.9 CDJ63780.1 - 9.2 5.1 9.3 11 4.9 9.3 1.0 1 0 0 1 1 1 0 Mitoguardin Pkinase PF00069.25 CDJ63781.1 - 1.2e-21 77.3 0.0 5.3e-16 58.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63781.1 - 1.4e-12 47.5 0.1 8e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Activator_LAG-3 PF11498.8 CDJ63781.1 - 0.039 12.9 14.7 0.069 12.1 14.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3412 PF11892.8 CDJ63781.1 - 0.1 12.7 0.2 0.26 11.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) DUF5061 PF16587.5 CDJ63782.1 - 0.0085 16.1 0.5 0.0085 16.1 0.5 1.7 1 1 1 2 2 2 1 17 kDa common-antigen outer membrane protein MAT1 PF06391.13 CDJ63782.1 - 0.046 13.6 12.0 0.054 13.3 12.0 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 CDK2AP PF09806.9 CDJ63782.1 - 0.33 11.0 15.5 0.5 10.4 15.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CCDC24 PF15669.5 CDJ63782.1 - 0.33 10.8 11.6 0.38 10.6 11.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Lin-8 PF03353.15 CDJ63782.1 - 0.35 10.4 13.7 0.39 10.2 13.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ63782.1 - 1.4 8.8 16.5 1.4 8.7 16.5 1.0 1 0 0 1 1 1 0 SPX domain RAP1 PF07218.11 CDJ63782.1 - 1.4 7.1 13.5 1.6 6.9 13.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DHHW PF14286.6 CDJ63782.1 - 2.1 7.6 5.7 2.6 7.3 5.7 1.1 1 0 0 1 1 1 0 DHHW protein FCP1_C PF09309.10 CDJ63782.1 - 2.4 8.0 17.3 2.9 7.7 16.8 1.5 1 1 0 1 1 1 0 FCP1, C-terminal Apt1 PF10351.9 CDJ63782.1 - 2.6 6.8 17.1 2.7 6.7 17.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1356 PF07092.12 CDJ63782.1 - 2.8 7.1 6.8 0.17 11.1 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) Macoilin PF09726.9 CDJ63782.1 - 3.8 6.0 19.1 4.2 5.8 19.1 1.1 1 0 0 1 1 1 0 Macoilin family CSG2 PF16965.5 CDJ63782.1 - 4 6.3 4.6 4.4 6.1 4.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator MDFI PF15316.6 CDJ63782.1 - 4.4 7.4 13.2 5.6 7.0 13.2 1.2 1 0 0 1 1 1 0 MyoD family inhibitor GP40 PF11025.8 CDJ63782.1 - 4.7 6.9 9.1 5.7 6.7 9.1 1.1 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium PNISR PF15996.5 CDJ63782.1 - 5.5 7.2 18.0 5.7 7.2 18.0 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Pap_E4 PF02711.14 CDJ63782.1 - 6.5 7.8 11.4 27 5.8 11.2 2.2 1 1 0 1 1 1 0 E4 protein Herpes_pp85 PF04637.12 CDJ63782.1 - 6.6 5.0 8.1 6.6 5.0 8.1 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) TFIIA PF03153.13 CDJ63782.1 - 6.6 6.6 23.6 7.8 6.4 23.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ63782.1 - 8.4 5.9 32.1 15 5.1 32.1 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAML PF14963.6 CDJ63782.1 - 9.6 6.2 10.1 12 6.0 10.1 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Spt20 PF12090.8 CDJ63783.1 - 2.1 7.9 15.0 2.6 7.6 15.0 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ63783.1 - 3.6 7.5 21.9 4 7.3 21.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tic110 PF16940.5 CDJ63783.1 - 6.6 5.1 22.6 8 4.8 22.6 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter FAM199X PF15814.5 CDJ63783.1 - 8.2 5.4 11.5 10 5.1 11.5 1.2 1 0 0 1 1 1 0 Protein family FAM199X TFIIA PF03153.13 CDJ63784.1 - 0.26 11.3 21.4 0.33 10.9 21.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ63785.1 - 2.7e-05 24.6 3.3 2.7e-05 24.6 3.3 10.3 2 2 3 6 6 6 1 Anti-sigma-K factor rskA M_domain PF12938.7 CDJ63785.1 - 0.0054 16.6 7.6 0.0054 16.6 7.6 9.8 7 3 1 8 8 8 2 M domain of GW182 DUF702 PF05142.12 CDJ63785.1 - 0.016 15.7 11.3 0.016 15.7 11.3 7.6 5 2 0 6 6 6 0 Domain of unknown function (DUF702) DUF572 PF04502.13 CDJ63785.1 - 0.15 11.6 27.7 0.017 14.8 8.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF572) UcrQ PF02939.16 CDJ63786.1 - 0.00078 19.3 0.4 0.001 18.9 0.4 1.2 1 0 0 1 1 1 1 UcrQ family DUF2722 PF10846.8 CDJ63788.1 - 0.00049 19.2 0.2 0.00095 18.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ63788.1 - 0.028 14.0 5.2 0.046 13.3 5.2 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ63788.1 - 1.7 8.5 8.8 0.098 12.6 0.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CDJ63789.1 - 5.1e-23 81.8 1.0 2.8e-11 43.3 0.0 2.9 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63789.1 - 3.5e-14 52.7 0.3 1.4e-06 27.8 0.0 2.8 3 1 0 3 3 3 2 Protein tyrosine kinase Exonuc_VII_L PF02601.15 CDJ63789.1 - 0.00096 18.8 18.8 0.0024 17.5 18.8 1.6 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF4667 PF15700.5 CDJ63789.1 - 0.14 12.3 25.8 0.28 11.2 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) MRP-S27 PF10037.9 CDJ63789.1 - 1.1 8.0 14.0 1.6 7.5 14.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 PA26 PF04636.13 CDJ63789.1 - 1.2 8.0 7.0 2.2 7.1 7.0 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Tho2 PF11262.8 CDJ63789.1 - 9.2 5.4 9.4 16 4.6 9.4 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2722 PF10846.8 CDJ63790.1 - 0.00024 20.2 7.9 0.00024 20.2 7.9 3.8 4 0 0 4 4 4 3 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ63790.1 - 0.0011 18.6 14.7 0.0011 18.6 14.7 3.2 3 0 0 3 3 3 2 Spt20 family Methyltrn_RNA_4 PF09936.9 CDJ63790.1 - 0.054 13.4 5.9 0.13 12.1 5.9 1.6 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Velvet PF11754.8 CDJ63790.1 - 0.28 11.1 15.2 0.34 10.8 2.6 3.2 3 0 0 3 3 3 0 Velvet factor DDHD PF02862.17 CDJ63790.1 - 1.7 8.8 14.9 1.6 8.8 4.8 2.8 3 0 0 3 3 3 0 DDHD domain Gti1_Pac2 PF09729.9 CDJ63790.1 - 4.1 7.5 11.1 20 5.2 0.0 2.7 3 0 0 3 3 3 0 Gti1/Pac2 family BORG_CEP PF14957.6 CDJ63790.1 - 7.8 7.7 13.5 15 6.7 0.1 3.5 3 0 0 3 3 3 0 Cdc42 effector TFIIA PF03153.13 CDJ63791.1 - 0.0054 16.8 63.1 0.0093 16.0 49.8 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ63791.1 - 0.0081 16.2 3.7 0.0081 16.2 3.7 6.5 3 2 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 S-antigen PF05756.11 CDJ63791.1 - 7.3 7.0 5.3 17 5.9 5.3 1.6 1 0 0 1 1 1 0 S-antigen protein DJ-1_PfpI PF01965.24 CDJ63792.1 - 1.9e-30 105.9 0.0 3.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family MIF4G PF02854.19 CDJ63792.1 - 1.8e-14 53.9 0.1 6.2e-11 42.4 0.1 2.7 1 1 0 1 1 1 1 MIF4G domain Upf2 PF04050.14 CDJ63792.1 - 1.5e-08 35.5 15.3 1.5e-08 35.5 15.3 3.5 3 0 0 3 3 3 1 Up-frameshift suppressor 2 DUF2722 PF10846.8 CDJ63792.1 - 0.00011 21.3 33.7 0.0028 16.7 3.7 4.1 4 0 0 4 4 4 4 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ63792.1 - 0.0034 17.0 8.3 0.0034 17.0 8.3 4.3 3 1 1 4 4 4 1 Spt20 family SUIM_assoc PF16619.5 CDJ63792.1 - 0.061 13.4 61.4 0.06 13.4 4.4 5.6 4 1 0 4 4 3 0 Unstructured region C-term to UIM in Ataxin3 FAM209 PF15206.6 CDJ63792.1 - 0.12 12.2 1.8 0.28 11.0 0.1 2.5 3 0 0 3 3 3 0 FAM209 family MSC PF09402.10 CDJ63792.1 - 0.2 11.1 5.5 0.16 11.4 3.2 2.0 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain TFIIA PF03153.13 CDJ63792.1 - 0.24 11.4 57.2 0.15 12.0 15.8 3.2 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ63792.1 - 0.48 11.4 24.3 1 10.3 0.7 4.7 4 1 0 4 4 3 0 Domain of unknown function (DUF4834) CDC45 PF02724.14 CDJ63792.1 - 1.9 6.7 16.6 0.32 9.2 10.3 2.4 3 0 0 3 3 3 0 CDC45-like protein Zn_peptidase PF04228.13 CDJ63792.1 - 6.7 6.1 18.2 0.05 13.0 0.8 3.4 3 0 0 3 3 3 0 Putative neutral zinc metallopeptidase MITF_TFEB_C_3_N PF15951.5 CDJ63792.1 - 8 7.1 40.0 0.49 11.0 4.4 4.5 5 0 0 5 5 4 0 MITF/TFEB/TFEC/TFE3 N-terminus RskA PF10099.9 CDJ63792.1 - 9.4 6.5 53.4 1.7 8.9 16.8 4.8 3 1 2 5 5 5 0 Anti-sigma-K factor rskA EphA2_TM PF14575.6 CDJ63793.1 - 8 7.4 6.1 45 5.0 2.1 3.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain UCH PF00443.29 CDJ63794.1 - 4.5e-14 52.6 0.0 4.5e-14 52.6 0.0 5.1 5 0 0 5 5 5 2 Ubiquitin carboxyl-terminal hydrolase Sin_N PF04801.13 CDJ63794.1 - 0.0043 16.3 0.0 0.0043 16.3 0.0 12.5 7 4 4 11 11 11 1 Sin-like protein conserved region DUF4378 PF14309.6 CDJ63795.1 - 0.00015 22.2 0.4 0.00034 21.0 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4378) DUF2722 PF10846.8 CDJ63795.1 - 0.00029 19.9 16.4 0.0036 16.3 6.2 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ63795.1 - 0.084 12.8 15.4 0.022 14.7 6.9 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Hep_59 PF07052.11 CDJ63795.1 - 0.088 13.6 4.3 3 8.6 0.7 2.8 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Peptidase_M13 PF01431.21 CDJ63795.1 - 0.31 10.6 6.7 0.82 9.2 6.7 1.6 1 0 0 1 1 1 0 Peptidase family M13 RAB3GAP2_N PF14655.6 CDJ63795.1 - 0.7 9.1 11.7 0.89 8.7 0.1 2.6 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Folliculin PF11704.8 CDJ63795.1 - 1.6 8.6 4.3 2.4 8.0 0.7 2.5 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF3464 PF11947.8 CDJ63795.1 - 4.5 7.0 6.4 3.5 7.4 0.7 2.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 RED_N PF07808.13 CDJ63795.1 - 4.6 6.7 8.5 26 4.3 4.8 2.6 2 0 0 2 2 2 0 RED-like protein N-terminal region DUF4834 PF16118.5 CDJ63795.1 - 4.6 8.3 12.1 11 7.1 4.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) EPL1 PF10513.9 CDJ63795.1 - 6.2 7.2 6.7 27 5.1 2.8 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like ANAPC_CDC26 PF10471.9 CDJ63795.1 - 8 7.4 37.4 1 10.2 4.3 4.0 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 DUF2722 PF10846.8 CDJ63796.1 - 0.00099 18.2 12.5 0.00099 18.2 12.5 4.7 4 1 0 4 4 4 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ63796.1 - 0.0051 16.5 17.5 0.0051 16.5 17.5 4.3 3 1 1 4 4 4 2 Spt20 family Pkinase PF00069.25 CDJ63798.1 - 7.3e-42 143.6 0.0 2.7e-27 95.8 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ63798.1 - 6.4e-23 81.4 0.1 1.4e-15 57.3 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase DUF4667 PF15700.5 CDJ63798.1 - 0.0012 19.0 8.6 0.0012 19.0 8.6 5.8 3 2 1 4 4 4 1 Domain of unknown function (DUF4667) Pkinase_fungal PF17667.1 CDJ63798.1 - 1.2 7.9 0.0 1.2 7.9 0.0 3.1 3 1 0 3 3 3 0 Fungal protein kinase DUF3677 PF12432.8 CDJ63799.1 - 0.018 15.3 0.2 0.051 13.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) PUF PF00806.19 CDJ63799.1 - 0.078 12.7 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Glyco_hydro_3_C PF01915.22 CDJ63799.1 - 0.93 9.4 7.0 0.12 12.4 2.8 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain SR-25 PF10500.9 CDJ63799.1 - 1.7 8.2 42.7 1.3 8.6 17.6 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Vps51 PF08700.11 CDJ63800.1 - 6.7e-18 64.5 0.9 1.2e-17 63.8 0.2 1.7 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 CDJ63800.1 - 3.3e-07 30.4 2.1 5.5e-07 29.7 2.1 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Dor1 PF04124.12 CDJ63800.1 - 5.2e-06 25.4 2.4 6.8e-06 25.0 2.4 1.1 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 CDJ63800.1 - 0.0075 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG5 PF10392.9 CDJ63800.1 - 0.18 12.0 3.0 0.31 11.2 3.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 RVT_1 PF00078.27 CDJ63802.1 - 0.00018 21.1 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3552 PF12072.8 CDJ63802.1 - 0.0043 16.5 0.7 0.007 15.8 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ArabFuran-catal PF09206.11 CDJ63802.1 - 0.11 11.7 0.1 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase B, catalytic RT_RNaseH PF17917.1 CDJ63803.1 - 2e-22 79.5 0.0 3.3e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ63803.1 - 3.7e-20 71.8 0.1 6.8e-20 71.0 0.1 1.5 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ63803.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like Integrase_H2C2 PF17921.1 CDJ63804.1 - 4e-18 65.3 2.6 3.8e-17 62.1 0.7 2.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CDJ63804.1 - 1.6e-14 54.1 0.0 4.9e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ63804.1 - 3.1e-05 24.1 0.3 3.1e-05 24.1 0.3 2.0 2 0 0 2 2 2 1 H2C2 zinc finger Laminin_G_3 PF13385.6 CDJ63806.1 - 9.4e-15 55.1 0.0 1.5e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 CDJ63806.1 - 3.1e-05 24.6 0.1 0.00012 22.6 0.0 2.1 2 1 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.23 CDJ63806.1 - 0.00012 22.2 0.0 0.00032 20.9 0.0 1.7 1 1 0 1 1 1 1 Laminin G domain Eno-Rase_FAD_bd PF07055.12 CDJ63807.1 - 2.7 8.5 5.8 33 5.0 0.2 3.4 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain Raco_middle PF17651.1 CDJ63807.1 - 8.3 6.1 7.1 1.5 8.5 0.7 3.0 3 0 0 3 3 3 0 RACo middle region DNA_pol_A PF00476.20 CDJ63808.1 - 4.1e-71 240.0 0.0 7e-70 236.0 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase family A SAGA-Tad1 PF12767.7 CDJ63808.1 - 1.1 9.0 8.5 2.1 8.0 8.5 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit V-SNARE_C PF12352.8 CDJ63809.1 - 9.1e-07 29.1 20.7 2.4e-06 27.8 1.4 3.7 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CDJ63809.1 - 0.0027 17.6 1.3 0.0027 17.6 1.3 3.8 3 1 2 5 5 5 1 Sec20 DUF3446 PF11928.8 CDJ63809.1 - 0.0062 16.8 7.0 0.0062 16.8 7.0 2.8 4 0 0 4 4 4 1 Early growth response N-terminal domain DUF2730 PF10805.8 CDJ63809.1 - 0.073 13.2 0.2 0.073 13.2 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) Dpy-30 PF05186.13 CDJ63810.1 - 6.2e-13 48.2 2.2 1.1e-12 47.4 2.2 1.4 1 0 0 1 1 1 1 Dpy-30 motif Spc7_N PF15402.6 CDJ63810.1 - 0.098 10.9 2.5 0.12 10.6 2.5 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 GHMP_kinases_N PF00288.26 CDJ63810.1 - 0.098 12.9 0.5 0.098 12.9 0.5 3.4 3 1 0 3 3 3 0 GHMP kinases N terminal domain TFIIA PF03153.13 CDJ63810.1 - 0.45 10.5 6.8 0.51 10.3 6.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ63810.1 - 0.5 10.5 7.7 0.95 9.6 7.7 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 CDJ63810.1 - 2 7.5 12.4 2.6 7.1 12.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2076 PF09849.9 CDJ63810.1 - 3.1 7.8 18.8 4 7.4 18.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Med15 PF09606.10 CDJ63810.1 - 4 6.0 14.0 4.7 5.8 14.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TraT PF05818.12 CDJ63811.1 - 0.00094 18.9 21.3 0.026 14.2 13.7 2.2 2 0 0 2 2 2 2 Enterobacterial TraT complement resistance protein SARAF PF06682.12 CDJ63811.1 - 0.0015 18.3 15.1 0.026 14.2 15.1 2.1 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Phage_holin_3_6 PF07332.11 CDJ63811.1 - 0.0028 17.7 7.8 0.045 13.8 2.5 2.2 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III RskA PF10099.9 CDJ63811.1 - 0.0065 16.8 27.6 0.0065 16.8 27.6 2.6 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Vfa1 PF08432.10 CDJ63811.1 - 0.097 13.0 23.8 0.061 13.6 13.2 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF2231 PF09990.9 CDJ63811.1 - 0.11 12.9 10.3 0.5 10.8 1.8 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF4179 PF13786.6 CDJ63811.1 - 0.13 12.7 18.3 1.4 9.4 1.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) Ctr PF04145.15 CDJ63811.1 - 0.13 12.8 12.5 0.052 14.2 4.2 2.1 2 0 0 2 2 2 0 Ctr copper transporter family TERB2 PF15101.6 CDJ63811.1 - 0.17 11.9 34.5 0.029 14.4 18.5 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 ASC PF00858.24 CDJ63811.1 - 0.39 9.6 5.0 0.51 9.2 5.0 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF3807 PF12720.7 CDJ63811.1 - 0.41 10.9 31.9 0.16 12.3 17.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) FPN1 PF06963.12 CDJ63811.1 - 0.63 8.5 9.3 0.61 8.6 2.5 2.0 2 0 0 2 2 2 0 Ferroportin1 (FPN1) DUF4386 PF14329.6 CDJ63811.1 - 0.9 9.4 11.9 1.5 8.6 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) ArsP_2 PF11449.8 CDJ63811.1 - 1.1 8.3 9.8 3.5 6.7 3.8 2.0 2 0 0 2 2 2 0 Putative, 10TM heavy-metal exporter SID-1_RNA_chan PF13965.6 CDJ63811.1 - 1.4 7.3 9.2 0.4 9.0 3.1 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 FHIPEP PF00771.20 CDJ63811.1 - 1.4 7.3 18.4 0.35 9.3 7.3 2.1 2 0 0 2 2 2 0 FHIPEP family eIF-3_zeta PF05091.12 CDJ63811.1 - 1.5 7.8 34.7 0.18 10.7 18.6 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Miga PF10265.9 CDJ63811.1 - 1.7 7.5 18.3 0.81 8.6 8.2 2.0 2 0 0 2 2 2 0 Mitoguardin PIEZO PF15917.5 CDJ63811.1 - 1.8 8.0 29.5 0.55 9.7 15.3 2.1 2 0 0 2 2 2 0 Piezo Peptidase_S49_N PF08496.10 CDJ63811.1 - 2 8.4 24.7 0.62 10.1 13.1 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RPN2_C PF18004.1 CDJ63811.1 - 2.5 8.0 27.2 0.45 10.4 15.6 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain NEMP PF10225.9 CDJ63811.1 - 2.7 7.6 9.7 1.7 8.2 2.7 2.0 2 0 0 2 2 2 0 NEMP family DUF2232 PF09991.9 CDJ63811.1 - 3.2 6.9 14.2 1.6 7.8 4.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) RR_TM4-6 PF06459.12 CDJ63811.1 - 3.8 7.2 26.3 1.3 8.8 15.2 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PNISR PF15996.5 CDJ63811.1 - 4 7.7 30.9 0.037 14.3 11.3 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR BAF1_ABF1 PF04684.13 CDJ63811.1 - 4.2 6.3 28.2 3.7 6.5 16.9 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF4551 PF15087.6 CDJ63811.1 - 4.4 6.0 18.7 5.4 5.7 18.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sec62 PF03839.16 CDJ63811.1 - 4.9 6.6 19.3 2.8 7.4 10.3 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 Oleosin PF01277.17 CDJ63811.1 - 5.7 6.7 11.8 9.7 6.0 3.6 2.3 2 0 0 2 2 2 0 Oleosin CPSF100_C PF13299.6 CDJ63811.1 - 6.1 7.0 25.5 0.78 9.9 13.3 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF1387 PF07139.11 CDJ63811.1 - 7.3 6.2 23.9 2.1 8.0 13.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) EPL1 PF10513.9 CDJ63811.1 - 7.4 6.9 28.1 0.88 9.9 14.0 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Ndc1_Nup PF09531.10 CDJ63811.1 - 7.4 5.1 31.9 9.5 4.8 31.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAE2 PF08573.10 CDJ63811.1 - 9.1 7.4 22.8 11 7.2 11.9 2.2 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus GDA1_CD39 PF01150.17 CDJ63812.1 - 3.2e-25 88.7 0.0 6.7e-24 84.3 0.0 2.0 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Spt20 PF12090.8 CDJ63813.1 - 0.49 10.0 6.0 0.5 9.9 6.0 1.1 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ63813.1 - 1.6 7.4 3.0 1.6 7.4 3.0 1.0 1 0 0 1 1 1 0 Presenilin RNase_PH PF01138.21 CDJ63814.1 - 1.5e-09 38.4 0.0 1.5e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 SOR PF07682.11 CDJ63814.1 - 0.08 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Sulphur oxygenase reductase RRM_1 PF00076.22 CDJ63816.1 - 6.4e-15 54.7 0.0 1.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ctr PF04145.15 CDJ63818.1 - 6.2e-16 59.4 13.0 2.6e-13 50.8 13.0 2.1 1 1 0 1 1 1 1 Ctr copper transporter family GLTP PF08718.11 CDJ63819.1 - 2.1e-24 86.5 0.0 2.6e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) SWIRM-assoc_2 PF16496.5 CDJ63820.1 - 0.17 10.7 7.2 0.23 10.3 7.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Reticulon PF02453.17 CDJ63822.1 - 3.2e-10 40.2 9.1 4.8e-10 39.6 8.8 1.4 1 1 0 1 1 1 1 Reticulon zf-PARP PF00645.18 CDJ63823.1 - 7.5e-07 29.9 0.1 2.2e-06 28.4 0.1 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region RAP1 PF07218.11 CDJ63823.1 - 8.7 4.5 6.5 11 4.1 6.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SNF2_N PF00176.23 CDJ63824.1 - 1.7e-16 59.9 0.0 1.8e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.23 CDJ63825.1 - 1.6e-21 76.4 0.1 1.1e-12 47.4 0.0 3.3 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ63825.1 - 4.7e-17 62.3 0.0 1.2e-16 61.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 CDJ63825.1 - 6.9e-07 29.5 1.3 6.9e-07 29.5 1.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CDJ63825.1 - 3.5e-05 24.0 1.5 3.5e-05 24.0 1.5 3.3 4 0 0 4 4 4 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ63825.1 - 9.1e-05 22.3 2.3 9.1e-05 22.3 2.3 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ63825.1 - 0.00025 21.0 0.1 0.00025 21.0 0.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ63825.1 - 0.0005 19.9 1.2 0.0005 19.9 1.2 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ63825.1 - 0.00074 19.5 1.0 0.0037 17.3 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CDJ63825.1 - 0.0019 17.9 4.2 0.0019 17.9 4.2 2.3 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 CDJ63825.1 - 0.0054 16.9 0.8 0.051 13.7 0.3 2.6 2 0 0 2 2 2 1 FANCL C-terminal domain UQ_con PF00179.26 CDJ63826.1 - 5e-44 149.3 0.0 6.4e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 CDJ63827.1 - 1.9e-13 50.2 0.0 6.4e-13 48.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Vps36-NZF-N PF16988.5 CDJ63827.1 - 0.11 11.8 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain WD40 PF00400.32 CDJ63828.1 - 9.9e-15 54.7 8.3 0.00024 21.8 0.9 5.4 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ63828.1 - 1.2e-08 35.1 0.0 0.67 10.3 0.0 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 CDJ63828.1 - 0.0028 17.1 0.0 0.0065 15.9 0.0 1.6 1 0 0 1 1 1 1 EF hand PQQ PF01011.21 CDJ63828.1 - 0.017 15.1 2.0 54 4.0 0.0 4.4 4 0 0 4 4 4 0 PQQ enzyme repeat Nup160 PF11715.8 CDJ63828.1 - 0.1 11.2 0.1 5.2 5.6 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF5046 PF16465.5 CDJ63828.1 - 0.15 11.5 0.0 6.4 6.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) EF-hand_6 PF13405.6 CDJ63828.1 - 0.18 11.8 0.0 0.51 10.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain PQQ_3 PF13570.6 CDJ63828.1 - 2.3 8.8 5.1 8.3 7.1 0.0 3.9 5 0 0 5 5 5 0 PQQ-like domain RCC1 PF00415.18 CDJ63829.1 - 2.5e-11 44.0 15.9 9.7e-05 22.9 1.3 6.8 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ63829.1 - 7.6e-11 41.5 23.6 0.00063 19.5 0.4 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PDEase_I PF00233.19 CDJ63830.1 - 6.7e-60 202.8 4.9 3.7e-29 102.1 0.0 2.5 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase CBM_48 PF02922.18 CDJ63831.1 - 5.7e-22 77.9 0.0 1.5e-20 73.4 0.0 3.0 3 0 0 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 CDJ63831.1 - 3.2e-19 69.2 0.0 1.8e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 CDJ63831.1 - 3.1e-13 50.0 0.9 0.00013 21.6 0.1 3.2 2 1 1 3 3 3 3 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 CDJ63831.1 - 0.0078 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DND1_DSRM PF14709.7 CDJ63832.1 - 0.27 11.5 2.3 1.8 8.9 0.0 3.1 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsRBD2 PF17842.1 CDJ63832.1 - 1.7 8.8 12.3 0.56 10.4 0.4 3.2 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 DUF45 PF01863.17 CDJ63832.1 - 3.9 7.4 7.5 1.3 9.0 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF45 OB_NTP_bind PF07717.16 CDJ63833.1 - 7.3e-17 61.5 0.0 1.7e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ63833.1 - 5.9e-14 52.4 0.0 1.3e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 CDJ63833.1 - 3.8e-13 49.7 0.9 1.4e-12 47.8 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 CDJ63833.1 - 5.4e-08 32.8 0.1 1.1e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ63833.1 - 3.8e-05 24.0 0.1 9.6e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDJ63833.1 - 0.0085 15.2 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 CDJ63833.1 - 0.012 15.3 0.0 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDJ63833.1 - 0.025 14.9 0.7 0.077 13.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CDJ63833.1 - 0.026 13.8 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 CDJ63833.1 - 0.027 14.3 1.1 6.6 6.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 CDJ63833.1 - 0.043 13.8 0.0 0.86 9.6 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CDJ63833.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 CDJ63833.1 - 0.063 13.7 1.5 0.22 11.9 0.4 2.5 2 1 0 2 2 2 0 AAA ATPase domain Tyr_Deacylase PF02580.16 CDJ63834.1 - 5.3e-46 156.7 0.0 6.3e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase C2 PF00168.30 CDJ63835.1 - 7.2e-14 51.9 0.5 2.6e-11 43.7 0.1 3.5 4 0 0 4 4 4 2 C2 domain DUF4667 PF15700.5 CDJ63836.1 - 0.0062 16.7 1.1 0.0062 16.7 1.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ63836.1 - 0.55 10.2 10.3 0.97 9.4 10.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M55 PF04951.13 CDJ63836.1 - 0.59 9.5 3.5 5.6 6.3 0.0 3.1 3 0 0 3 3 3 0 D-aminopeptidase Bromodomain PF00439.25 CDJ63837.1 - 8e-07 29.1 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Citrate_bind PF16114.5 CDJ63838.1 - 2e-76 255.4 0.0 3.3e-76 254.7 0.0 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 CDJ63838.1 - 6.5e-20 71.5 0.0 6.5e-20 71.5 0.0 3.0 3 1 1 4 4 4 1 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 CDJ63838.1 - 6.8e-13 48.7 0.0 6.8e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 CoA-ligase CoA_binding PF02629.19 CDJ63838.1 - 5.7e-07 30.1 0.0 1.8e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 CDJ63838.1 - 0.00011 21.8 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain SUIM_assoc PF16619.5 CDJ63838.1 - 0.00025 21.0 35.5 0.26 11.4 6.6 4.4 4 0 0 4 4 4 3 Unstructured region C-term to UIM in Ataxin3 Dehydrin PF00257.19 CDJ63838.1 - 0.021 15.4 0.2 0.021 15.4 0.2 3.6 3 0 0 3 3 3 0 Dehydrin Phage_holin_3_2 PF04550.12 CDJ63839.1 - 0.091 13.3 0.7 0.4 11.3 0.4 2.2 1 1 0 1 1 1 0 Phage holin family 2 NUDIX_2 PF13869.6 CDJ63839.1 - 0.29 10.7 3.2 0.27 10.8 0.3 2.3 2 0 0 2 2 2 0 Nucleotide hydrolase AAA_lid_7 PF17867.1 CDJ63842.1 - 0.0095 16.1 0.3 0.019 15.2 0.3 1.5 1 0 0 1 1 1 1 Midasin AAA lid domain Sugar_tr PF00083.24 CDJ63842.1 - 0.015 14.2 0.2 0.015 14.2 0.2 2.2 2 1 0 2 2 2 0 Sugar (and other) transporter DUF2722 PF10846.8 CDJ63842.1 - 0.021 13.8 4.4 0.027 13.4 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FAM177 PF14774.6 CDJ63842.1 - 0.026 14.9 0.1 0.045 14.1 0.1 1.3 1 0 0 1 1 1 0 FAM177 family RR_TM4-6 PF06459.12 CDJ63842.1 - 0.23 11.3 4.3 0.41 10.4 4.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Roughex PF06020.11 CDJ63842.1 - 0.27 10.3 7.7 0.39 9.8 7.7 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF913 PF06025.12 CDJ63842.1 - 0.34 9.8 2.9 0.42 9.6 2.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TYW3 PF02676.14 CDJ63842.1 - 0.37 10.1 3.9 0.49 9.7 3.9 1.3 1 0 0 1 1 1 0 Methyltransferase TYW3 Hid1 PF12722.7 CDJ63842.1 - 0.7 7.9 4.1 0.78 7.8 4.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 CDJ63842.1 - 0.9 8.7 4.4 0.11 11.6 0.2 1.5 1 1 1 2 2 2 0 ZIP Zinc transporter Striatin PF08232.12 CDJ63842.1 - 1.5 9.4 15.7 0.28 11.8 11.8 1.7 1 1 1 2 2 2 0 Striatin family CNDH2_M PF16869.5 CDJ63842.1 - 2.3 8.9 8.7 0.5 11.1 4.2 2.0 2 0 0 2 2 2 0 PF16858 Draxin PF15550.6 CDJ63842.1 - 3.8 7.3 8.4 5.3 6.8 8.4 1.1 1 0 0 1 1 1 0 Draxin Ndc1_Nup PF09531.10 CDJ63842.1 - 7.9 5.0 9.7 11 4.6 9.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sugar_tr PF00083.24 CDJ63843.1 - 1.6e-39 136.0 42.0 9.5e-25 87.4 22.3 3.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDJ63843.1 - 9.3e-09 34.7 7.1 9.3e-09 34.7 7.1 4.0 2 2 3 5 5 5 3 Major Facilitator Superfamily GNVR PF13807.6 CDJ63843.1 - 2 8.4 3.3 9.6 6.2 0.0 2.8 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase EF-hand_1 PF00036.32 CDJ63844.1 - 4.9e-30 100.8 8.4 1.4e-07 30.5 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ63844.1 - 2.4e-25 88.8 6.1 7.2e-12 45.6 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ63844.1 - 8.7e-25 84.5 5.3 5.1e-06 26.0 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ63844.1 - 3.3e-21 73.8 10.7 1e-06 28.0 0.2 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 CDJ63844.1 - 1.1e-15 57.2 10.5 0.00012 21.8 1.5 4.3 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ63844.1 - 5.5e-08 33.1 2.9 0.00087 19.6 0.4 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDJ63844.1 - 3.5e-07 30.1 4.8 0.00029 20.8 0.8 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.25 CDJ63844.1 - 8.6e-07 28.6 0.0 2.2e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain EF-hand_10 PF14788.6 CDJ63844.1 - 0.00084 19.2 1.9 1.5 8.8 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 CDJ63844.1 - 0.0021 18.3 0.5 0.13 12.6 0.1 3.0 2 1 0 2 2 2 1 EF-hand domain MIF4G PF02854.19 CDJ63844.1 - 0.058 13.0 0.1 0.082 12.5 0.1 1.3 1 0 0 1 1 1 0 MIF4G domain AlaDh_PNT_C PF01262.21 CDJ63845.1 - 1.4e-33 116.0 0.3 2.6e-33 115.2 0.2 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CDJ63845.1 - 1.5e-21 77.1 0.1 1.1e-11 45.2 0.0 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, N-terminal domain NAD_binding_7 PF13241.6 CDJ63845.1 - 0.00051 20.5 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 CDJ63845.1 - 0.00087 18.6 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ63845.1 - 0.00097 17.9 0.3 0.0017 17.2 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.18 CDJ63845.1 - 0.003 17.5 0.0 0.0076 16.2 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 CDJ63845.1 - 0.0066 15.6 0.6 0.01 14.9 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CDJ63845.1 - 0.0076 15.5 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CDJ63845.1 - 0.011 16.3 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ63845.1 - 0.023 13.8 1.1 0.037 13.1 1.1 1.3 1 0 0 1 1 1 0 FAD binding domain XdhC_C PF13478.6 CDJ63845.1 - 0.088 13.3 0.2 0.21 12.1 0.1 1.8 2 0 0 2 2 1 0 XdhC Rossmann domain FAD_oxidored PF12831.7 CDJ63845.1 - 0.27 10.6 5.2 0.43 9.9 5.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ63845.1 - 1.5 9.1 3.8 0.48 10.7 0.5 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Adeno_PIX PF03955.14 CDJ63845.1 - 3.6 7.8 14.4 0.12 12.5 7.6 2.2 2 1 0 2 2 1 0 Adenovirus hexon-associated protein (IX) Methyltransf_25 PF13649.6 CDJ63846.1 - 6.4e-07 30.0 0.0 0.00011 22.9 0.0 3.0 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ63846.1 - 1.2e-06 29.0 0.0 0.00013 22.5 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ63846.1 - 1.9e-06 27.8 0.0 0.0012 18.7 0.0 3.6 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ63846.1 - 5.8e-05 23.8 0.0 0.001 19.8 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Spermine_synth PF01564.17 CDJ63846.1 - 0.00043 19.7 0.0 0.027 13.9 0.0 3.0 2 1 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 CDJ63846.1 - 0.00067 19.5 0.0 0.027 14.3 0.0 2.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ63846.1 - 0.26 11.3 0.1 0.73 9.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MmgE_PrpD PF03972.14 CDJ63847.1 - 6e-08 31.7 0.0 6.8e-08 31.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family TFIIA PF03153.13 CDJ63849.1 - 1.9 8.4 6.6 2.3 8.1 6.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IMCp PF12314.8 CDJ63850.1 - 1.4e-23 82.9 67.0 5.3e-16 58.7 24.4 6.3 3 2 3 6 6 6 4 Inner membrane complex protein AF-4 PF05110.13 CDJ63850.1 - 9.3e-05 20.7 9.4 0.00013 20.3 9.4 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein DUF4228 PF14009.6 CDJ63850.1 - 0.34 11.3 6.8 4.6 7.6 0.8 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4228) SR-25 PF10500.9 CDJ63850.1 - 0.39 10.3 21.5 0.61 9.7 21.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ63850.1 - 1.1 10.0 15.7 2.4 8.9 15.7 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF755 PF05501.11 CDJ63850.1 - 4.8 7.5 22.0 7.4 6.9 22.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2722 PF10846.8 CDJ63851.1 - 2.3e-05 23.6 1.5 2.3e-05 23.6 1.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) DUF4667 PF15700.5 CDJ63851.1 - 0.0028 17.8 2.3 0.27 11.3 1.4 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4667) IMUP PF15761.5 CDJ63851.1 - 0.017 15.8 8.9 0.017 15.8 8.9 3.2 4 0 0 4 4 4 0 Immortalisation up-regulated protein Med15 PF09606.10 CDJ63851.1 - 0.75 8.4 36.4 0.055 12.2 15.8 2.5 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ63851.1 - 0.82 9.2 33.2 0.014 15.0 16.6 2.3 2 0 0 2 2 2 0 Spt20 family Roughex PF06020.11 CDJ63851.1 - 2.5 7.1 6.8 4.8 6.2 6.8 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF4834 PF16118.5 CDJ63851.1 - 7.9 7.5 12.7 0.38 11.8 5.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) dUTPase PF00692.19 CDJ63852.1 - 1.5e-16 60.3 0.0 2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 dUTPase EF-hand_7 PF13499.6 CDJ63853.1 - 8.3e-05 23.0 5.8 0.012 16.1 0.5 1.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ63853.1 - 0.00034 20.3 1.7 0.0012 18.6 1.5 2.0 1 1 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CDJ63853.1 - 0.0035 16.8 1.7 0.0071 15.8 1.2 1.8 1 1 1 2 2 2 1 EF hand EF-hand_5 PF13202.6 CDJ63853.1 - 0.0091 15.5 1.3 0.018 14.5 1.3 1.5 1 0 0 1 1 1 1 EF hand Adap_comp_sub PF00928.21 CDJ63853.1 - 0.084 12.2 0.0 0.084 12.2 0.0 1.0 1 0 0 1 1 1 0 Adaptor complexes medium subunit family Tcp10_C PF07202.13 CDJ63854.1 - 1.3e-05 25.2 0.0 8.1e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 T-complex protein 10 C-terminus Chromo PF00385.24 CDJ63855.1 - 5.4e-11 42.2 0.0 4.2e-10 39.4 0.0 2.0 1 1 1 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-RING_2 PF13639.6 CDJ63856.1 - 3.3e-13 49.7 6.2 8.7e-13 48.4 6.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ63856.1 - 6.3e-10 38.7 5.9 1.8e-09 37.3 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ63856.1 - 3.5e-08 33.0 5.5 3.5e-08 33.0 5.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 CDJ63856.1 - 2e-07 30.8 2.9 5.3e-07 29.5 2.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CDJ63856.1 - 3.5e-07 30.4 7.9 4.7e-06 26.8 7.9 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ63856.1 - 3.8e-07 29.9 3.9 8.8e-07 28.7 3.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ63856.1 - 6e-06 26.0 5.5 1.3e-05 24.9 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ63856.1 - 0.0001 22.3 1.1 0.0001 22.3 1.1 2.4 1 1 1 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CDJ63856.1 - 0.0037 16.9 6.9 0.0081 15.8 6.9 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 CDJ63856.1 - 0.026 14.2 3.5 0.078 12.6 3.5 1.8 1 1 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.6 CDJ63856.1 - 0.051 13.4 8.0 0.15 12.0 8.0 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDJ63856.1 - 0.06 13.4 5.1 0.19 11.8 5.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CDJ63856.1 - 0.14 12.3 4.0 0.54 10.4 4.0 2.1 1 1 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 CDJ63856.1 - 0.29 11.2 4.4 0.78 9.8 4.4 1.8 1 0 0 1 1 1 0 Zinc-finger RecR PF02132.15 CDJ63856.1 - 0.72 9.5 3.5 27 4.4 0.0 2.6 2 0 0 2 2 2 0 RecR protein Pex14_N PF04695.13 CDJ63857.1 - 0.0015 19.2 0.0 0.0019 18.9 0.0 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4179 PF13786.6 CDJ63857.1 - 0.14 12.7 2.1 0.3 11.6 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Calpain_inhib PF00748.19 CDJ63857.1 - 0.16 12.5 5.0 0.19 12.2 5.0 1.1 1 0 0 1 1 1 0 Calpain inhibitor IHABP4_N PF16174.5 CDJ63857.1 - 0.52 10.9 3.5 0.64 10.6 3.5 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF3138 PF11336.8 CDJ63857.1 - 5.6 5.5 10.0 6.7 5.2 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) BAF1_ABF1 PF04684.13 CDJ63857.1 - 9.9 5.1 6.6 11 5.0 6.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TPR_8 PF13181.6 CDJ63858.1 - 0.026 14.7 0.9 9.4 6.7 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SR-25 PF10500.9 CDJ63859.1 - 0.0056 16.3 14.7 0.0072 16.0 14.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein FixG_C PF11614.8 CDJ63859.1 - 0.11 12.8 3.3 0.13 12.4 3.3 1.1 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Cyt_bd_oxida_II PF02322.15 CDJ63860.1 - 0.0073 15.7 3.0 0.0086 15.5 3.0 1.2 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II ThrE PF06738.12 CDJ63860.1 - 0.027 13.9 7.7 0.033 13.6 7.7 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter AP3D1 PF06375.11 CDJ63860.1 - 1.2 9.4 15.5 0.17 12.1 11.5 1.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 CLN3 PF02487.17 CDJ63860.1 - 6.8 5.6 14.6 0.69 8.9 10.2 1.5 2 0 0 2 2 2 0 CLN3 protein Connexin PF00029.19 CDJ63860.1 - 7.4 6.3 13.1 3.9 7.2 11.1 1.5 2 0 0 2 2 2 0 Connexin Nop25 PF09805.9 CDJ63861.1 - 0.00026 21.5 0.9 0.00027 21.4 0.9 1.2 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) SKA1 PF07160.12 CDJ63861.1 - 0.22 11.4 8.6 0.29 10.9 8.6 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 TFIIA PF03153.13 CDJ63861.1 - 0.32 10.9 15.0 0.32 10.9 15.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDP_N PF12278.8 CDJ63861.1 - 0.94 9.6 25.4 0.038 14.1 16.0 2.1 2 0 0 2 2 2 0 Sex determination protein N terminal DUF2756 PF10956.8 CDJ63861.1 - 1 9.9 21.1 1.4 9.5 21.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Cwf_Cwc_15 PF04889.12 CDJ63861.1 - 1.1 8.9 9.0 0.08 12.7 4.5 1.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SPX PF03105.19 CDJ63861.1 - 1.2 8.9 19.2 1.6 8.5 19.2 1.1 1 0 0 1 1 1 0 SPX domain CHDCT2 PF08074.11 CDJ63861.1 - 1.6 8.9 8.4 1.2 9.3 7.3 1.3 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain Spt20 PF12090.8 CDJ63861.1 - 1.9 8.0 16.0 2.6 7.6 16.0 1.2 1 0 0 1 1 1 0 Spt20 family DUF2572 PF10833.8 CDJ63861.1 - 4.3 7.1 11.8 5.9 6.6 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Pheromone PF08015.11 CDJ63861.1 - 5.8 8.0 20.4 4.1 8.5 11.9 2.3 2 0 0 2 2 2 0 Fungal mating-type pheromone Vasculin PF15337.6 CDJ63861.1 - 7.8 7.4 25.1 5.8 7.8 18.1 2.5 2 1 0 2 2 2 0 Vascular protein family Vasculin-like 1 KH_1 PF00013.29 CDJ63863.1 - 1.8e-05 24.4 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 KH domain PT PF04886.12 CDJ63863.1 - 0.14 11.7 0.2 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 PT repeat RSRP PF17069.5 CDJ63863.1 - 2.4 7.7 30.3 3.1 7.3 30.3 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 WXG100 PF06013.12 CDJ63865.1 - 0.018 15.3 0.2 0.041 14.1 0.2 1.6 1 0 0 1 1 1 0 Proteins of 100 residues with WXG ApoL PF05461.11 CDJ63865.1 - 0.028 13.7 0.5 0.044 13.1 0.5 1.3 1 0 0 1 1 1 0 Apolipoprotein L EF-hand_1 PF00036.32 CDJ63866.1 - 3.7e-18 63.7 0.1 2.3e-05 23.6 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CDJ63866.1 - 2.1e-15 56.9 0.0 8.6e-08 32.5 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ63866.1 - 1.7e-13 49.4 0.3 4.7e-05 22.7 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CDJ63866.1 - 8.8e-12 44.0 0.3 7.4e-05 22.4 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CDJ63866.1 - 1.9e-11 43.6 1.1 0.002 18.0 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair Dockerin_1 PF00404.18 CDJ63866.1 - 0.0079 16.4 3.4 0.27 11.5 0.0 3.3 3 1 0 3 3 3 1 Dockerin type I domain EF-hand_9 PF14658.6 CDJ63866.1 - 0.13 12.6 0.0 10 6.6 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain G6PD_C PF02781.16 CDJ63867.1 - 4e-99 331.5 0.0 4.5e-99 331.3 0.0 1.0 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Pantoate_transf PF02548.15 CDJ63868.1 - 2.3e-81 273.0 1.4 2.3e-81 273.0 1.4 1.7 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.11 CDJ63868.1 - 1.8e-11 44.3 0.3 4.4e-11 43.1 0.3 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CDJ63868.1 - 5.4e-10 39.1 0.1 4.6e-09 36.1 0.1 2.4 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PEP_mutase PF13714.6 CDJ63868.1 - 0.0025 17.3 0.1 0.0051 16.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Methyltr_RsmB-F PF01189.17 CDJ63870.1 - 3.1e-24 85.7 0.0 2e-13 50.4 0.0 3.4 3 0 0 3 3 3 3 16S rRNA methyltransferase RsmB/F Popeye PF04831.13 CDJ63872.1 - 3.2e-11 43.6 0.0 4.6e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 CDJ63872.1 - 0.00023 21.2 0.2 0.038 14.1 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain CRAL_TRIO PF00650.20 CDJ63873.1 - 6.4e-21 74.7 0.0 1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain XhlA PF10779.9 CDJ63874.1 - 0.076 13.2 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Haemolysin XhlA OB_NTP_bind PF07717.16 CDJ63875.1 - 2.9e-13 50.0 0.1 1.3e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CDJ63875.1 - 7.5e-08 32.6 3.7 1.5e-07 31.7 0.0 3.0 2 1 1 3 3 3 1 Helicase associated domain (HA2) RED_C PF07807.11 CDJ63875.1 - 1.3 9.5 4.3 2.7 8.5 4.3 1.4 1 0 0 1 1 1 0 RED-like protein C-terminal region Tim17 PF02466.19 CDJ63876.1 - 1.6e-08 34.9 1.3 1.8e-08 34.8 0.4 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Rep_fac-A_C PF08646.10 CDJ63878.1 - 1.1e-26 93.4 0.1 2.3e-26 92.3 0.1 1.5 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CDJ63878.1 - 2.5e-15 56.2 0.0 5.5e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 CDJ63878.1 - 0.007 16.3 0.0 21 5.2 0.0 3.4 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain DZR PF12773.7 CDJ63878.1 - 0.011 15.8 1.1 0.029 14.4 1.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon PLATZ PF04640.14 CDJ63878.1 - 0.12 13.1 0.8 0.4 11.3 0.8 2.0 1 0 0 1 1 1 0 PLATZ transcription factor Importin_rep PF18773.1 CDJ63878.1 - 0.18 11.5 0.4 19 5.0 0.1 2.6 2 0 0 2 2 2 0 Importin 13 repeat SAS-6_N PF16531.5 CDJ63880.1 - 3.4e-28 98.1 3.2 6.5e-28 97.2 3.2 1.5 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal CSD PF00313.22 CDJ63880.1 - 0.091 12.6 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain TIP49 PF06068.13 CDJ63881.1 - 6.1e-158 525.6 0.1 7.5e-158 525.3 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CDJ63881.1 - 1.3e-17 63.7 0.3 3.5e-16 59.1 0.3 3.0 1 1 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CDJ63881.1 - 1.5e-12 48.0 0.1 2.2e-08 34.6 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ63881.1 - 5.2e-10 39.3 0.3 4.9e-07 29.6 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ63881.1 - 1.8e-06 28.3 0.1 0.1 12.8 0.0 2.8 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CDJ63881.1 - 1.1e-05 25.8 0.0 0.00048 20.6 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ63881.1 - 3.5e-05 23.8 0.1 0.0058 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CDJ63881.1 - 0.00015 22.2 0.1 0.063 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CDJ63881.1 - 0.00035 20.3 0.1 0.18 11.5 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CDJ63881.1 - 0.00085 18.8 0.2 0.036 13.5 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CDJ63881.1 - 0.001 19.6 0.0 0.0031 18.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain DnaB_C PF03796.15 CDJ63881.1 - 0.0018 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CDJ63881.1 - 0.0029 17.4 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 CDJ63881.1 - 0.0034 17.7 0.0 0.0076 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ63881.1 - 0.0038 17.3 0.1 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 CDJ63881.1 - 0.0044 16.6 0.0 0.0079 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDJ63881.1 - 0.0048 16.9 0.0 3.9 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CDJ63881.1 - 0.0054 16.0 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 CDJ63881.1 - 0.0061 16.4 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDJ63881.1 - 0.0073 16.5 0.0 0.05 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDJ63881.1 - 0.0075 15.8 0.8 0.04 13.4 0.0 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region Rad17 PF03215.15 CDJ63881.1 - 0.012 15.5 0.1 0.078 12.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 CDJ63881.1 - 0.016 15.7 0.0 0.036 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ63881.1 - 0.018 14.3 0.1 0.047 13.0 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 CDJ63881.1 - 0.021 13.9 0.1 0.046 12.8 0.1 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 CDJ63881.1 - 0.024 14.3 0.1 0.37 10.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CDJ63881.1 - 0.028 14.3 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 CDJ63881.1 - 0.031 13.7 0.1 0.062 12.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 CDJ63881.1 - 0.034 14.5 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 CDJ63881.1 - 0.035 14.0 0.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 CDJ63881.1 - 0.044 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 CDJ63881.1 - 0.048 13.0 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 CDJ63881.1 - 0.058 13.8 0.2 0.42 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain PIF1 PF05970.14 CDJ63881.1 - 0.058 12.6 0.1 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase TniB PF05621.11 CDJ63881.1 - 0.068 12.6 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein T2SSE PF00437.20 CDJ63881.1 - 0.077 12.0 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein IPT PF01745.16 CDJ63881.1 - 0.11 11.8 0.1 0.28 10.6 0.1 1.6 1 0 0 1 1 1 0 Isopentenyl transferase TsaE PF02367.17 CDJ63881.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CDJ63881.1 - 0.15 12.2 0.0 4.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 CDJ63883.1 - 1.6e-22 80.5 0.0 2.9e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CDJ63883.1 - 1.1e-21 77.3 21.9 1.9e-21 76.4 21.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_25 PF13481.6 CDJ63883.1 - 8.8e-05 22.2 1.5 0.07 12.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CDJ63883.1 - 0.001 19.6 0.0 0.0017 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ63883.1 - 0.0026 18.2 0.1 0.0048 17.3 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CDJ63883.1 - 0.0039 17.7 0.0 0.0064 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 CDJ63883.1 - 0.0063 16.4 0.0 0.053 13.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DAP10 PF07213.11 CDJ63883.1 - 0.012 15.5 0.4 4.4 7.3 0.0 3.2 2 0 0 2 2 2 0 DAP10 membrane protein RsgA_GTPase PF03193.16 CDJ63883.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CDJ63883.1 - 0.02 15.1 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CDJ63883.1 - 0.026 14.5 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC2_membrane_3 PF12698.7 CDJ63883.1 - 0.031 13.4 23.6 0.014 14.6 20.9 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein AAA_28 PF13521.6 CDJ63883.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NIL PF09383.10 CDJ63883.1 - 0.07 13.0 0.1 0.21 11.5 0.1 1.8 2 0 0 2 2 1 0 NIL domain AAA_30 PF13604.6 CDJ63883.1 - 0.075 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 CDJ63883.1 - 0.077 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.22 CDJ63883.1 - 0.094 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 CDJ63883.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDJ63883.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 CDJ63883.1 - 0.14 12.1 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 CDJ63883.1 - 0.16 11.7 0.0 0.5 10.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CDJ63883.1 - 0.18 11.5 0.0 0.5 10.1 0.0 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Helicase_C PF00271.31 CDJ63884.1 - 3.4e-09 37.0 0.0 2.2e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ63884.1 - 0.038 13.8 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Complex1_LYR_2 PF13233.6 CDJ63884.1 - 0.14 12.9 0.8 0.39 11.5 0.8 1.7 1 0 0 1 1 1 0 Complex1_LYR-like DUF737 PF05300.11 CDJ63884.1 - 1.6 9.1 4.7 1.3 9.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DUF974 PF06159.13 CDJ63885.1 - 9.5e-30 104.2 0.3 3.7e-26 92.4 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF974) Peptidase_M16 PF00675.20 CDJ63886.1 - 2.1e-43 147.9 0.5 1.3e-42 145.3 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 CDJ63886.1 - 1.5e-26 93.3 0.0 5.2e-26 91.6 0.0 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CDJ63886.1 - 8.3e-21 74.8 0.2 3.8e-08 33.5 0.0 3.9 4 0 0 4 4 4 3 Peptidase M16 inactive domain Curlin_rpt PF07012.12 CDJ63886.1 - 0.097 12.7 0.6 8.3 6.5 0.0 2.8 2 0 0 2 2 2 0 Curlin associated repeat Asp PF00026.23 CDJ63887.1 - 2.5e-24 86.3 0.0 1.5e-13 50.9 0.0 4.0 2 1 1 3 3 3 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ63887.1 - 0.066 13.4 0.0 12 6.1 0.0 2.9 3 1 0 3 3 3 0 Xylanase inhibitor N-terminal TMEM247 PF15444.6 CDJ63888.1 - 5.4 7.0 5.8 11 6.0 5.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 Amidohydro_2 PF04909.14 CDJ63889.1 - 1.5e-10 41.4 0.0 3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 CDJ63889.1 - 0.00023 20.6 3.4 0.0028 17.0 3.0 2.6 2 1 0 2 2 2 1 Amidohydrolase family V-SNARE_C PF12352.8 CDJ63890.1 - 1.4e-07 31.7 2.2 1.4e-07 31.7 2.2 2.1 3 0 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 CDJ63890.1 - 0.0036 15.3 8.1 0.0062 14.6 8.1 1.5 1 1 0 1 1 1 1 Prominin Synaptobrevin PF00957.21 CDJ63890.1 - 0.0071 16.1 1.4 0.012 15.4 0.2 2.0 2 0 0 2 2 2 1 Synaptobrevin PEP-utilisers_N PF05524.13 CDJ63890.1 - 0.0096 16.1 0.6 0.0096 16.1 0.6 2.6 2 1 1 3 3 3 1 PEP-utilising enzyme, N-terminal Sec20 PF03908.13 CDJ63890.1 - 0.021 14.8 0.4 0.021 14.8 0.4 2.3 2 1 0 3 3 3 0 Sec20 SHNi-TPR PF10516.9 CDJ63890.1 - 0.028 13.9 0.1 0.071 12.6 0.1 1.7 1 0 0 1 1 1 0 SHNi-TPR DASH_Duo1 PF08651.10 CDJ63890.1 - 0.096 12.5 1.7 8.7 6.2 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 Tox-URI2 PF15653.6 CDJ63890.1 - 0.1 12.8 1.1 0.66 10.3 0.1 2.3 1 1 1 2 2 2 0 URI fold toxin 2 XhlA PF10779.9 CDJ63890.1 - 0.24 11.6 3.4 3.6 7.9 1.1 2.6 2 0 0 2 2 2 0 Haemolysin XhlA VPS38 PF17649.1 CDJ63890.1 - 0.49 9.2 5.2 0.42 9.4 4.3 1.3 1 1 0 1 1 1 0 Vacuolar protein sorting 38 Laminin_II PF06009.12 CDJ63890.1 - 1.1 9.3 8.3 2.6 8.1 0.9 2.7 2 2 0 2 2 2 0 Laminin Domain II DUF4279 PF14106.6 CDJ63890.1 - 2.1 8.6 4.9 6.9 6.9 0.2 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4279) FlaC_arch PF05377.11 CDJ63890.1 - 2.5 8.6 5.1 27 5.2 0.2 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 CDJ63890.1 - 3.4 8.0 8.7 3.8 7.9 0.7 3.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DinB_2 PF12867.7 CDJ63890.1 - 7.9 7.0 7.4 18 5.9 0.2 3.2 2 1 1 3 3 3 0 DinB superfamily Ribosomal_L28 PF00830.19 CDJ63892.1 - 1.3e-07 31.7 0.9 3.4e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal L28 family DUF2053 PF09767.9 CDJ63893.1 - 1.6e-25 90.1 4.1 2.1e-25 89.8 4.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) MitMem_reg PF13012.6 CDJ63894.1 - 0.044 14.2 0.1 0.95 9.9 0.0 2.9 3 1 1 4 4 4 0 Maintenance of mitochondrial structure and function MCU PF04678.13 CDJ63894.1 - 3.6 7.7 5.7 8.3 6.5 1.1 2.5 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Siah-Interact_N PF09032.11 CDJ63895.1 - 0.079 13.3 1.4 0.19 12.1 1.4 1.6 1 0 0 1 1 1 0 Siah interacting protein, N terminal RNF111_N PF15303.6 CDJ63895.1 - 0.18 11.5 3.1 0.14 11.9 0.3 2.0 1 1 1 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus SUIM_assoc PF16619.5 CDJ63896.1 - 0.11 12.6 9.9 0.52 10.4 9.9 2.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Leu_zip PF15294.6 CDJ63896.1 - 0.25 10.8 4.2 0.41 10.1 4.2 1.2 1 0 0 1 1 1 0 Leucine zipper Spt20 PF12090.8 CDJ63896.1 - 0.39 10.3 6.4 0.8 9.3 6.4 1.4 1 0 0 1 1 1 0 Spt20 family SET PF00856.28 CDJ63896.1 - 1.3 9.3 0.0 1.3 9.3 0.0 4.8 2 2 1 3 3 3 0 SET domain SR-25 PF10500.9 CDJ63897.1 - 0.0066 16.1 4.1 0.0066 16.1 4.1 8.6 7 3 1 9 9 9 1 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ63898.1 - 0.001 19.1 4.4 0.0011 19.0 4.4 1.2 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 CcmE PF03100.15 CDJ63898.1 - 0.037 14.0 0.1 0.042 13.8 0.1 1.1 1 0 0 1 1 1 0 CcmE Spt20 PF12090.8 CDJ63898.1 - 0.13 11.9 6.0 0.11 12.1 6.0 1.1 1 0 0 1 1 1 0 Spt20 family R_equi_Vir PF05526.11 CDJ63898.1 - 0.84 9.5 6.1 0.89 9.4 6.1 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein TFIIA PF03153.13 CDJ63898.1 - 1.5 8.7 14.2 1.5 8.7 14.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ63898.1 - 2.4 8.4 17.9 2.7 8.2 17.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ63899.1 - 0.0031 17.1 19.2 0.0039 16.8 19.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2076 PF09849.9 CDJ63899.1 - 0.032 14.3 37.3 0.041 13.9 37.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4647 PF15504.6 CDJ63899.1 - 0.065 12.3 26.0 0.079 12.1 26.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Presenilin PF01080.17 CDJ63899.1 - 0.39 9.4 25.8 0.45 9.2 25.8 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ63899.1 - 0.87 8.5 22.4 0.98 8.4 22.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PAT1 PF09770.9 CDJ63899.1 - 0.97 7.6 34.0 1.1 7.5 34.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SARAF PF06682.12 CDJ63899.1 - 1.5 8.4 19.7 2.1 7.9 19.7 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF908 PF06012.12 CDJ63899.1 - 2 7.8 20.2 3 7.2 20.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4551 PF15087.6 CDJ63899.1 - 2.1 7.1 18.7 2.4 6.9 18.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ALMT PF11744.8 CDJ63899.1 - 2.5 6.8 16.3 3.2 6.5 16.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter BAF1_ABF1 PF04684.13 CDJ63899.1 - 2.7 7.0 19.5 3.2 6.7 19.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ASD2 PF08687.11 CDJ63899.1 - 2.8 7.4 22.6 3.5 7.1 22.6 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Hydin_ADK PF17213.3 CDJ63899.1 - 2.8 8.2 18.5 4 7.7 18.5 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Neur_chan_memb PF02932.16 CDJ63899.1 - 2.8 7.9 16.9 4.2 7.4 16.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2489 PF10675.9 CDJ63899.1 - 2.9 7.8 35.6 0.05 13.5 11.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Asp-B-Hydro_N PF05279.11 CDJ63899.1 - 5.1 7.1 14.7 6.4 6.8 14.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hid1 PF12722.7 CDJ63899.1 - 6.3 4.8 24.2 7.3 4.6 24.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 CDJ63899.1 - 6.6 4.9 21.1 7.8 4.6 21.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 CDJ63899.1 - 7.6 4.5 18.2 10 4.1 18.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MDM10 PF12519.8 CDJ63899.1 - 8.4 5.1 21.9 11 4.7 21.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Raftlin PF15250.6 CDJ63899.1 - 9.3 4.9 19.7 11 4.7 19.7 1.0 1 0 0 1 1 1 0 Raftlin WD40 PF00400.32 CDJ63900.1 - 8.2e-07 29.6 0.2 4.5e-06 27.3 0.1 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat SPX PF03105.19 CDJ63900.1 - 0.0054 16.7 12.0 0.0054 16.7 12.0 5.1 2 2 1 3 3 3 1 SPX domain RskA PF10099.9 CDJ63901.1 - 0.00048 20.5 20.4 0.00048 20.5 20.4 6.0 1 1 2 5 5 5 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ63902.1 - 9.6e-05 22.1 15.9 9.6e-05 22.1 15.9 11.1 8 2 2 11 11 11 5 Nuclear RNA-splicing-associated protein AIMP2_LysRS_bd PF16780.5 CDJ63902.1 - 0.11 12.3 0.9 0.55 10.0 0.0 2.8 2 0 0 2 2 2 0 AIMP2 lysyl-tRNA synthetase binding domain RskA PF10099.9 CDJ63903.1 - 7.2e-05 23.1 21.6 0.0019 18.6 21.6 2.3 1 1 0 1 1 1 1 Anti-sigma-K factor rskA Pex14_N PF04695.13 CDJ63903.1 - 3.6 8.2 34.2 2.1 9.0 18.7 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peroxin-3 PF04882.12 CDJ63904.1 - 0.096 11.7 0.7 0.1 11.6 0.7 1.0 1 0 0 1 1 1 0 Peroxin-3 AAA_33 PF13671.6 CDJ63904.1 - 0.27 11.4 5.8 0.25 11.5 0.8 2.2 1 1 1 2 2 2 0 AAA domain Macoilin PF09726.9 CDJ63905.1 - 0.00067 18.3 15.0 0.00091 17.9 15.0 1.2 1 0 0 1 1 1 1 Macoilin family SPX PF03105.19 CDJ63905.1 - 0.0012 18.8 16.4 0.0014 18.6 16.4 1.1 1 0 0 1 1 1 1 SPX domain DUF4342 PF14242.6 CDJ63905.1 - 0.011 15.7 2.3 0.028 14.4 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Presenilin PF01080.17 CDJ63905.1 - 0.02 13.7 17.0 0.026 13.3 17.0 1.3 1 0 0 1 1 1 0 Presenilin ABC2_membrane_2 PF12679.7 CDJ63905.1 - 0.03 13.6 2.2 0.038 13.3 2.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein MDM10 PF12519.8 CDJ63905.1 - 0.036 13.0 9.8 0.035 13.0 9.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Cwf_Cwc_15 PF04889.12 CDJ63905.1 - 0.039 13.7 16.0 0.052 13.3 16.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Apt1 PF10351.9 CDJ63905.1 - 0.051 12.4 10.3 0.051 12.4 10.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S64 PF08192.11 CDJ63905.1 - 0.053 12.0 16.7 0.06 11.8 16.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 MMR1 PF08505.10 CDJ63905.1 - 0.057 13.7 19.6 0.08 13.2 19.6 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Auxin_canalis PF05703.11 CDJ63905.1 - 0.098 12.6 24.3 0.15 11.9 24.3 1.3 1 0 0 1 1 1 0 Auxin canalisation SpoIIP PF07454.11 CDJ63905.1 - 0.2 11.1 14.2 0.26 10.7 14.2 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Peptidase_U57 PF05582.12 CDJ63905.1 - 0.2 10.9 9.0 0.25 10.5 9.0 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Ureide_permease PF07168.11 CDJ63905.1 - 0.28 9.9 10.6 0.55 8.9 10.6 1.5 1 0 0 1 1 1 0 Ureide permease PAT1 PF09770.9 CDJ63905.1 - 0.3 9.3 26.9 0.35 9.1 26.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4746 PF15928.5 CDJ63905.1 - 0.4 10.0 7.7 0.45 9.9 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PAP1 PF08601.10 CDJ63905.1 - 0.46 10.1 19.0 0.58 9.8 19.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Lin-8 PF03353.15 CDJ63905.1 - 0.6 9.6 21.5 0.84 9.1 21.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PGK PF00162.19 CDJ63905.1 - 0.83 8.5 4.9 0.84 8.5 2.7 1.8 1 1 0 2 2 2 0 Phosphoglycerate kinase PCM1_C PF15717.5 CDJ63905.1 - 0.84 8.3 22.4 1 7.9 22.4 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus V_ATPase_I PF01496.19 CDJ63905.1 - 1 7.2 13.7 1.1 7.1 13.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LptF_LptG PF03739.14 CDJ63905.1 - 1.2 7.9 3.1 1.5 7.6 3.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF4638 PF15472.6 CDJ63905.1 - 1.7 8.3 16.6 2.3 7.9 16.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) ALMT PF11744.8 CDJ63905.1 - 2.2 7.0 16.3 2.8 6.7 16.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ndc1_Nup PF09531.10 CDJ63905.1 - 2.4 6.7 17.3 2.6 6.6 17.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 CDJ63905.1 - 3.5 4.6 22.7 4.1 4.4 22.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Miga PF10265.9 CDJ63905.1 - 4.8 6.0 18.3 5.1 6.0 18.3 1.0 1 0 0 1 1 1 0 Mitoguardin Cellulose_synt PF03552.14 CDJ63905.1 - 7.6 4.9 6.2 7.8 4.8 6.2 1.1 1 0 0 1 1 1 0 Cellulose synthase CDC45 PF02724.14 CDJ63905.1 - 9.1 4.4 17.2 11 4.1 17.2 1.2 1 0 0 1 1 1 0 CDC45-like protein APG6_N PF17675.1 CDJ63906.1 - 0.00029 21.4 7.9 0.00029 21.4 7.9 2.4 2 1 1 3 3 3 1 Apg6 coiled-coil region NAM-associated PF14303.6 CDJ63906.1 - 0.011 16.4 0.2 0.011 16.4 0.2 5.7 2 1 2 4 4 4 0 No apical meristem-associated C-terminal domain Secretin_N_2 PF07655.13 CDJ63906.1 - 0.018 15.6 3.3 0.018 15.6 3.3 5.1 3 1 1 4 4 4 0 Secretin N-terminal domain IMUP PF15761.5 CDJ63906.1 - 0.035 14.8 12.4 0.035 14.8 12.4 8.1 4 1 2 6 6 6 0 Immortalisation up-regulated protein DUF508 PF04370.12 CDJ63906.1 - 0.042 13.6 0.6 0.042 13.6 0.6 5.1 3 1 2 5 5 5 0 Domain of unknown function (DUF508) DUF4482 PF14818.6 CDJ63906.1 - 0.18 12.7 0.1 0.18 12.7 0.1 4.5 2 2 2 4 4 4 0 Domain of unknown function (DUF4482) RskA PF10099.9 CDJ63907.1 - 0.00027 21.3 21.5 0.0029 17.9 21.6 2.0 1 1 0 1 1 1 1 Anti-sigma-K factor rskA PsbQ PF05757.11 CDJ63907.1 - 0.0019 18.0 4.7 0.0019 18.0 4.7 1.8 1 1 1 2 2 2 1 Oxygen evolving enhancer protein 3 (PsbQ) TFIIA PF03153.13 CDJ63907.1 - 0.027 14.5 28.2 0.036 14.1 28.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ63907.1 - 0.034 13.7 16.1 0.042 13.4 16.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc24 PF08286.11 CDJ63907.1 - 0.042 14.1 5.2 0.067 13.4 5.2 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 eIF-3_zeta PF05091.12 CDJ63907.1 - 0.042 12.8 7.7 0.04 12.9 7.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_23 PF13476.6 CDJ63907.1 - 0.11 12.9 11.4 0.15 12.6 11.4 1.2 1 0 0 1 1 1 0 AAA domain Spt20 PF12090.8 CDJ63907.1 - 0.12 12.0 29.2 0.2 11.2 29.2 1.3 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ63907.1 - 0.24 10.3 23.8 0.4 9.6 23.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NEMP PF10225.9 CDJ63907.1 - 0.28 10.8 3.0 0.35 10.5 3.0 1.3 1 0 0 1 1 1 0 NEMP family RIFIN PF02009.16 CDJ63907.1 - 0.43 10.4 8.4 0.57 10.0 8.4 1.2 1 0 0 1 1 1 0 Rifin Presenilin PF01080.17 CDJ63907.1 - 0.61 8.8 8.8 0.7 8.6 8.8 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ63907.1 - 0.92 9.5 5.9 1.1 9.3 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ63907.1 - 0.96 9.2 8.9 1.3 8.7 8.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Mcm10 PF09332.11 CDJ63907.1 - 1.2 8.5 20.0 0.14 11.6 15.4 1.6 2 0 0 2 2 2 0 Mcm10 replication factor LMBR1 PF04791.16 CDJ63907.1 - 1.7 7.4 3.2 1.7 7.5 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein F1F0-ATPsyn_F PF10791.9 CDJ63907.1 - 2.3 8.7 4.6 1.9 9.0 2.5 2.0 2 1 0 2 2 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi DUF3573 PF12097.8 CDJ63907.1 - 2.5 6.8 7.6 2.9 6.6 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Hydin_ADK PF17213.3 CDJ63907.1 - 4.5 7.5 11.8 6.6 7.0 11.8 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Menin PF05053.13 CDJ63907.1 - 4.9 5.4 11.4 5.9 5.1 11.4 1.0 1 0 0 1 1 1 0 Menin FliD_N PF02465.18 CDJ63907.1 - 5.1 7.9 22.7 0.36 11.5 11.4 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus GREB1 PF15782.5 CDJ63907.1 - 6.8 3.7 15.2 8.1 3.4 15.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EMC3_TMCO1 PF01956.16 CDJ63907.1 - 7.6 6.2 9.6 10 5.8 9.6 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RskA PF10099.9 CDJ63908.1 - 0.0087 16.4 8.7 0.01 16.1 8.7 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ63908.1 - 2.5 6.8 6.2 2.7 6.6 6.2 1.0 1 0 0 1 1 1 0 Presenilin CDK2AP PF09806.9 CDJ63908.1 - 4.5 7.3 20.9 4.3 7.3 4.5 2.0 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein IMS PF00817.20 CDJ63909.1 - 4.1e-31 108.0 0.0 6e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family TFIIA PF03153.13 CDJ63909.1 - 0.072 13.1 24.0 0.1 12.6 24.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 CDJ63909.1 - 0.075 12.4 7.3 0.1 11.9 7.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Roughex PF06020.11 CDJ63909.1 - 0.085 11.9 8.8 0.11 11.5 8.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ63909.1 - 0.43 10.2 30.4 0.62 9.6 30.4 1.1 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ63909.1 - 0.63 11.0 9.1 1 10.4 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Hydin_ADK PF17213.3 CDJ63909.1 - 0.64 10.3 5.8 1 9.6 5.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Neur_chan_memb PF02932.16 CDJ63909.1 - 0.8 9.7 3.5 1.2 9.2 3.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Activator_LAG-3 PF11498.8 CDJ63909.1 - 0.85 8.5 28.4 1.2 8.0 28.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Band_3_cyto PF07565.13 CDJ63909.1 - 0.88 9.3 6.6 0.6 9.9 5.1 1.3 2 0 0 2 2 1 0 Band 3 cytoplasmic domain SpoIIP PF07454.11 CDJ63909.1 - 1.2 8.5 6.1 1.7 8.0 6.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) UPF0560 PF10577.9 CDJ63909.1 - 1.6 7.2 12.3 2 6.8 12.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TERB2 PF15101.6 CDJ63909.1 - 1.7 8.7 11.0 2.4 8.1 11.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CCDC53 PF10152.9 CDJ63909.1 - 2.3 8.6 9.9 1.2 9.5 7.5 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RR_TM4-6 PF06459.12 CDJ63909.1 - 2.4 7.9 6.2 0.73 9.6 2.9 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 CDJ63909.1 - 2.5 8.0 12.2 3.5 7.5 12.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ63909.1 - 3.8 6.2 9.6 5.4 5.7 9.6 1.1 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.6 CDJ63909.1 - 4.7 7.1 14.4 7 6.5 14.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF2722 PF10846.8 CDJ63909.1 - 6.1 5.7 28.3 8.7 5.2 28.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PAT1 PF09770.9 CDJ63909.1 - 6.7 4.9 15.2 8.9 4.4 15.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ63909.1 - 7.5 3.5 6.9 10 3.1 6.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF-3_zeta PF05091.12 CDJ63909.1 - 8.9 5.2 10.8 12 4.7 10.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4148 PF13663.6 CDJ63910.1 - 0.031 14.4 17.8 1.4 9.1 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) XPA_N PF01286.18 CDJ63911.1 - 0.13 12.3 0.6 1.2 9.2 0.2 2.0 2 0 0 2 2 2 0 XPA protein N-terminal DUF572 PF04502.13 CDJ63912.1 - 0.0095 15.6 13.2 0.015 15.0 13.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) DNA_pol_B_palm PF14792.6 CDJ63912.1 - 0.09 13.0 0.2 0.24 11.6 0.2 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm MMR1 PF08505.10 CDJ63912.1 - 0.12 12.7 20.5 0.1 12.8 7.4 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Lin-8 PF03353.15 CDJ63912.1 - 0.38 10.3 23.5 0.14 11.7 9.0 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist GNAT_acetyltr_2 PF13718.6 CDJ63912.1 - 0.69 9.3 7.1 2.1 7.7 3.7 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Mlh1_C PF16413.5 CDJ63912.1 - 0.76 9.1 10.4 1.1 8.6 4.8 2.1 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus DUF2072 PF09845.9 CDJ63912.1 - 0.79 10.0 8.0 3.9 7.7 3.2 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein MecA PF05389.12 CDJ63912.1 - 0.83 9.2 9.9 2.4 7.7 4.9 2.2 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) YABBY PF04690.13 CDJ63912.1 - 1.6 9.3 15.4 0.093 13.3 3.3 2.5 3 0 0 3 3 2 0 YABBY protein DUF3464 PF11947.8 CDJ63912.1 - 1.6 8.4 17.9 1 9.1 8.0 2.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 TFB6 PF17110.5 CDJ63912.1 - 2.1 8.1 6.5 2.7 7.7 2.4 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Connexin PF00029.19 CDJ63912.1 - 2.8 7.6 9.7 6.4 6.5 4.4 2.1 2 0 0 2 2 2 0 Connexin MDM10 PF12519.8 CDJ63912.1 - 3.4 6.4 10.4 0.79 8.5 3.0 2.1 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 SpoIIP PF07454.11 CDJ63912.1 - 3.5 7.0 16.2 1.7 8.1 6.9 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4569 PF15133.6 CDJ63912.1 - 3.6 7.2 18.9 2.8 7.6 8.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) PA26 PF04636.13 CDJ63912.1 - 4 6.3 11.1 3.4 6.5 6.4 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Apt1 PF10351.9 CDJ63912.1 - 4.9 5.9 10.3 5.7 5.7 2.3 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain RR_TM4-6 PF06459.12 CDJ63912.1 - 5 6.9 16.4 2.6 7.8 5.9 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 AIF_C PF14721.6 CDJ63912.1 - 5.1 7.5 11.3 3.2 8.1 3.0 2.7 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Rxt3 PF08642.10 CDJ63912.1 - 5.7 7.7 8.7 8.4 7.2 2.4 2.5 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 EIIBC-GUT_N PF03612.14 CDJ63912.1 - 6.1 6.5 15.3 0.91 9.2 4.6 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Thg1C PF14413.6 CDJ63912.1 - 6.4 7.0 11.9 22 5.2 0.1 2.4 2 0 0 2 2 2 0 Thg1 C terminal domain OATP PF03137.20 CDJ63912.1 - 6.5 4.9 11.6 4.5 5.5 0.6 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family eIF-3_zeta PF05091.12 CDJ63912.1 - 6.8 5.5 25.9 1.5 7.8 3.4 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peroxin-13_N PF04088.13 CDJ63912.1 - 7.1 6.9 9.1 13 6.0 3.8 2.5 2 0 0 2 2 2 0 Peroxin 13, N-terminal region FAM60A PF15396.6 CDJ63912.1 - 7.3 6.5 12.7 16 5.4 6.3 2.3 2 0 0 2 2 2 0 Protein Family FAM60A DUF3408 PF11888.8 CDJ63912.1 - 8.2 6.6 18.6 5 7.3 8.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) WBP-1 PF11669.8 CDJ63912.1 - 9.1 7.0 12.1 4.6 7.9 3.7 2.8 2 0 0 2 2 2 0 WW domain-binding protein 1 WD40 PF00400.32 CDJ63913.1 - 0.0015 19.3 0.0 0.006 17.4 0.0 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF4179 PF13786.6 CDJ63913.1 - 0.27 11.7 2.5 1.1 9.8 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) SUIM_assoc PF16619.5 CDJ63913.1 - 0.52 10.4 20.8 0.97 9.5 6.7 3.3 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SDP_N PF12278.8 CDJ63913.1 - 0.7 10.0 14.8 0.27 11.4 4.2 2.3 2 0 0 2 2 2 0 Sex determination protein N terminal DUF4667 PF15700.5 CDJ63913.1 - 2.5 8.2 12.5 1.6 8.7 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) GREB1 PF15782.5 CDJ63913.1 - 7 3.6 13.3 9.5 3.2 13.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ63913.1 - 9.2 5.7 9.9 13 5.3 1.0 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ63914.1 - 0.056 13.4 48.2 0.079 12.9 48.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ63914.1 - 0.1 12.9 33.9 0.068 13.5 20.3 2.8 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ63915.1 - 2.4e-05 24.1 32.9 0.00046 19.9 3.0 3.3 3 0 0 3 3 3 3 Spt20 family DUF2722 PF10846.8 CDJ63915.1 - 0.0029 16.6 1.6 0.0029 16.6 1.6 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) DUF5345 PF17280.2 CDJ63915.1 - 0.11 12.5 0.2 0.11 12.5 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5345) Cwf_Cwc_15 PF04889.12 CDJ63915.1 - 0.67 9.6 16.9 0.28 10.9 9.3 2.8 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF4667 PF15700.5 CDJ63915.1 - 0.9 9.6 26.5 5.2 7.1 2.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) Neur_chan_memb PF02932.16 CDJ63915.1 - 5.7 6.9 13.6 12 5.8 5.9 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 CDJ63915.1 - 8.8 5.1 16.5 8.5 5.1 0.6 2.9 2 1 0 2 2 2 0 Golgi-body localisation protein domain Ribosomal_S9 PF00380.19 CDJ63916.1 - 2.8e-18 66.6 0.1 3.5e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.18 CDJ63917.1 - 1.1e-73 247.0 6.7 4.8e-73 244.8 6.7 2.2 1 0 0 1 1 1 1 Ribosomal protein L13e CENP-Q PF13094.6 CDJ63917.1 - 0.0095 16.1 5.6 0.0095 16.1 5.6 5.4 4 1 1 5 5 5 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF5082 PF16888.5 CDJ63917.1 - 0.061 13.6 11.9 0.028 14.7 2.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DUF2730 PF10805.8 CDJ63917.1 - 0.073 13.2 13.1 0.28 11.3 0.5 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) betaPIX_CC PF16523.5 CDJ63917.1 - 0.12 12.2 9.6 0.19 11.6 6.6 2.9 2 0 0 2 2 2 0 betaPIX coiled coil COG7 PF10191.9 CDJ63917.1 - 1.8 6.7 8.4 0.086 11.1 1.4 2.0 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) zf-CCCH PF00642.24 CDJ63918.1 - 2.1e-06 27.5 15.2 0.019 14.9 0.5 3.8 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ63918.1 - 1.8e-05 24.4 7.4 0.0038 17.0 0.8 3.5 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_5 PF18384.1 CDJ63918.1 - 0.018 15.1 2.9 2.8 8.1 0.9 3.0 2 0 0 2 2 2 0 Unkempt Zinc finger domain 1 (Znf1) zf_CCCH_4 PF18345.1 CDJ63918.1 - 0.087 12.9 15.5 0.25 11.5 0.4 4.3 3 1 0 3 3 3 0 Zinc finger domain DUF3568 PF12092.8 CDJ63919.1 - 0.46 10.6 3.4 0.81 9.8 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) RNA_polI_A14 PF08203.11 CDJ63919.1 - 0.72 10.6 4.0 1.7 9.4 0.2 3.9 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 DUF4335 PF14233.6 CDJ63919.1 - 2.8 7.8 6.0 0.82 9.6 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4335) CRAL_TRIO PF00650.20 CDJ63922.1 - 1.8e-31 109.0 0.0 2.5e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ63922.1 - 5.3e-06 26.6 0.1 8.5e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CDJ63922.1 - 0.0023 18.1 1.4 0.0066 16.6 0.3 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DnaJ PF00226.31 CDJ63923.1 - 3.3e-17 62.3 9.5 5.7e-17 61.6 2.7 3.8 3 1 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.31 CDJ63923.1 - 5.6e-17 61.7 0.4 1.3e-08 34.9 0.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ63923.1 - 2.5e-07 30.8 9.2 0.0032 17.7 0.0 3.9 4 0 0 4 4 4 2 Myb-like DNA-binding domain TMEM237 PF15383.6 CDJ63923.1 - 0.023 13.8 0.1 0.023 13.8 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 237 Exonuc_VII_L PF02601.15 CDJ63923.1 - 0.41 10.2 14.8 0.012 15.2 3.9 2.6 2 1 0 2 2 2 0 Exonuclease VII, large subunit FancD2 PF14631.6 CDJ63923.1 - 1.2 6.5 11.2 2.2 5.6 11.2 1.4 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SAP PF02037.27 CDJ63924.1 - 2.9e-06 26.9 0.0 7.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 SAP domain FtsL PF04999.13 CDJ63924.1 - 0.15 12.1 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Cell division protein FtsL zinc_ribbon_6 PF14599.6 CDJ63925.1 - 5e-22 77.7 1.7 5e-22 77.7 1.7 4.0 4 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 CDJ63925.1 - 3.7e-18 65.8 20.7 3.7e-18 65.8 20.7 4.3 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 CDJ63925.1 - 1.7e-07 31.4 5.0 1.7e-07 31.4 5.0 5.8 4 1 1 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ63925.1 - 3e-07 30.3 3.0 3e-07 30.3 3.0 4.5 4 2 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ63925.1 - 3.8e-05 23.5 4.1 3.8e-05 23.5 4.1 5.6 2 1 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ63925.1 - 4.9e-05 23.2 7.5 4.9e-05 23.2 7.5 5.9 4 2 2 6 6 6 2 zinc-RING finger domain zf-RING_11 PF17123.5 CDJ63925.1 - 0.0026 17.4 2.2 0.0026 17.4 2.2 5.0 8 0 0 8 8 8 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CDJ63925.1 - 0.0029 17.7 1.9 0.0029 17.7 1.9 5.3 5 2 0 5 5 5 1 zinc finger of C3HC4-type, RING GcpE PF04551.14 CDJ63925.1 - 4 6.4 5.3 22 4.0 5.0 1.9 1 1 0 1 1 1 0 GcpE protein PA PF02225.22 CDJ63926.1 - 6.4e-07 29.3 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 PA domain Myb_DNA-bind_7 PF15963.5 CDJ63928.1 - 2.9e-21 75.1 0.1 2.9e-21 75.1 0.1 2.1 2 0 0 2 2 2 1 Myb DNA-binding like HMG_box_2 PF09011.10 CDJ63928.1 - 8.8e-10 39.0 1.0 5.5e-05 23.7 0.1 2.9 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 CDJ63928.1 - 3.5e-07 30.5 0.1 0.00067 20.0 0.1 2.8 2 0 0 2 2 2 2 HMG (high mobility group) box Myb_DNA-binding PF00249.31 CDJ63928.1 - 0.009 16.2 0.1 0.032 14.4 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain ApoLp-III PF07464.11 CDJ63930.1 - 0.38 10.8 5.4 3.9 7.6 1.8 3.3 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) RabGAP-TBC PF00566.18 CDJ63931.1 - 5.9e-44 150.3 0.2 1.1e-43 149.5 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain YabA PF06156.13 CDJ63931.1 - 0.12 13.1 0.9 0.31 11.7 0.9 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Exo70 PF03081.15 CDJ63932.1 - 0.053 12.6 0.0 0.071 12.1 0.0 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Wbp11 PF09429.10 CDJ63933.1 - 1.6e-14 54.1 6.8 1.9e-14 53.8 6.8 1.1 1 0 0 1 1 1 1 WW domain binding protein 11 MCM_bind PF09739.9 CDJ63934.1 - 0.11 10.9 1.7 0.17 10.3 1.7 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Dynein_light PF01221.18 CDJ63936.1 - 1.5e-05 25.2 0.0 2.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Serinc PF03348.15 CDJ63937.1 - 4.9 6.0 9.7 5.3 5.9 9.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) O-antigen_lig PF13425.6 CDJ63937.1 - 6.8 5.4 4.4 7.1 5.3 4.4 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SpoIIE PF07228.12 CDJ63938.1 - 0.0003 20.8 6.3 0.0054 16.7 3.4 2.8 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) SR-25 PF10500.9 CDJ63938.1 - 0.0024 17.5 45.8 0.063 12.9 12.3 3.5 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein MelC1 PF06236.11 CDJ63938.1 - 0.021 14.9 0.7 0.021 14.9 0.7 9.2 6 2 3 9 9 4 0 Tyrosinase co-factor MelC1 AAA_23 PF13476.6 CDJ63938.1 - 0.49 10.9 14.3 0.8 10.2 14.3 1.3 1 0 0 1 1 1 0 AAA domain MDM31_MDM32 PF08118.11 CDJ63938.1 - 0.51 9.0 5.9 0.96 8.0 5.9 1.4 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins MRP-S27 PF10037.9 CDJ63938.1 - 1.1 8.1 12.9 1.7 7.4 12.9 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 SpoIIP PF07454.11 CDJ63938.1 - 1.5 8.2 11.1 3.3 7.1 11.1 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) 5_nucleotid PF05761.14 CDJ63938.1 - 1.9 7.3 10.1 2.9 6.7 10.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family V_ATPase_I PF01496.19 CDJ63938.1 - 2.2 6.1 9.9 3.6 5.4 9.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4770 PF15994.5 CDJ63938.1 - 4.4 7.5 14.8 0.46 10.7 9.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) CDC14 PF08045.11 CDJ63938.1 - 5.1 6.1 14.4 0.68 9.0 6.3 2.7 3 0 0 3 3 3 0 Cell division control protein 14, SIN component UPF0564 PF10595.9 CDJ63938.1 - 6.1 5.8 24.3 0.4 9.7 19.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 Rxt3 PF08642.10 CDJ63938.1 - 6.8 7.5 6.8 88 3.9 5.9 2.7 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 eIF-3_zeta PF05091.12 CDJ63938.1 - 6.9 5.5 13.0 13 4.6 13.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BORG_CEP PF14957.6 CDJ63938.1 - 8.9 7.5 21.6 9.4 7.4 5.2 3.5 3 0 0 3 3 3 0 Cdc42 effector CDC45 PF02724.14 CDJ63939.1 - 0.0032 15.8 5.0 0.0054 15.1 5.0 1.4 1 0 0 1 1 1 1 CDC45-like protein TFIIA PF03153.13 CDJ63939.1 - 0.017 15.2 70.8 0.033 14.2 54.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AbLIM_anchor PF16182.5 CDJ63939.1 - 0.018 14.9 7.8 0.034 14.0 7.8 1.4 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM Presenilin PF01080.17 CDJ63939.1 - 0.049 12.4 19.1 0.0075 15.1 14.2 1.9 2 0 0 2 2 2 0 Presenilin Otopetrin PF03189.13 CDJ63939.1 - 0.071 11.9 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Otopetrin eIF-3_zeta PF05091.12 CDJ63939.1 - 0.098 11.6 23.7 0.0087 15.1 15.9 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ABC2_membrane_2 PF12679.7 CDJ63939.1 - 0.28 10.4 0.0 0.28 10.4 0.0 2.2 3 0 0 3 3 2 0 ABC-2 family transporter protein CCSAP PF15748.5 CDJ63939.1 - 0.35 11.0 22.9 0.17 12.0 19.2 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Neur_chan_memb PF02932.16 CDJ63939.1 - 0.54 10.3 12.3 0.086 12.9 7.7 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TCP PF03634.13 CDJ63939.1 - 0.82 10.2 18.3 0.18 12.3 13.5 2.1 2 0 0 2 2 2 0 TCP family transcription factor SID-1_RNA_chan PF13965.6 CDJ63939.1 - 1.2 7.4 4.6 1.7 7.0 4.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SpoIIP PF07454.11 CDJ63939.1 - 1.4 8.3 21.3 0.075 12.5 14.8 1.8 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Endostatin PF06482.11 CDJ63939.1 - 1.4 8.3 16.5 0.47 9.9 13.1 1.8 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin SLC12 PF03522.15 CDJ63939.1 - 1.7 7.6 15.3 0.34 9.9 11.6 1.6 2 0 0 2 2 2 0 Solute carrier family 12 Hid1 PF12722.7 CDJ63939.1 - 2.3 6.2 14.7 4 5.5 14.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EPL1 PF10513.9 CDJ63939.1 - 2.6 8.4 20.9 0.82 10.0 14.5 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Serinc PF03348.15 CDJ63939.1 - 3.5 6.5 8.5 5.5 5.8 8.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4770 PF15994.5 CDJ63939.1 - 4.1 7.6 24.0 2.4 8.3 19.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Plasmodium_Vir PF05795.11 CDJ63939.1 - 5.9 6.2 7.7 10 5.4 7.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CTU2 PF10288.9 CDJ63939.1 - 6.2 7.1 17.6 5.1 7.4 13.1 2.4 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Rrn6 PF10214.9 CDJ63939.1 - 6.4 5.1 26.1 0.18 10.3 19.5 1.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor FAM91_C PF14648.6 CDJ63939.1 - 7 5.4 7.9 2.6 6.8 5.4 1.4 2 0 0 2 2 2 0 FAM91 C-terminus Zip PF02535.22 CDJ63939.1 - 8.1 5.6 6.5 13 4.9 6.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.5 CDJ63939.1 - 8.6 3.3 21.7 12 2.9 21.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RskA PF10099.9 CDJ63940.1 - 0.0014 19.0 13.6 0.002 18.5 13.6 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ63940.1 - 0.035 13.7 25.0 0.039 13.6 25.0 1.2 1 0 0 1 1 1 0 Spt20 family Peptidase_S15 PF02129.18 CDJ63940.1 - 0.18 11.3 8.7 0.22 11.1 8.7 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PMSI1 PF15322.6 CDJ63940.1 - 0.34 10.3 9.5 0.46 9.9 9.5 1.4 1 1 0 1 1 1 0 Protein missing in infertile sperm 1, putative TFIIA PF03153.13 CDJ63940.1 - 1.1 9.1 32.8 1.3 9.0 32.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ63940.1 - 3.1 7.5 6.5 3.3 7.4 6.5 1.1 1 0 0 1 1 1 0 Connexin eIF-3_zeta PF05091.12 CDJ63940.1 - 4.1 6.3 15.1 3.9 6.3 15.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EOS1 PF12326.8 CDJ63940.1 - 4.3 7.2 6.5 4.4 7.2 6.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein PAT1 PF09770.9 CDJ63940.1 - 4.4 5.5 23.1 5.1 5.2 23.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.10 CDJ63940.1 - 4.5 5.8 27.8 5 5.7 27.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.17 CDJ63940.1 - 7.3 6.7 10.6 8.6 6.4 10.6 1.2 1 0 0 1 1 1 0 DDHD domain LCIB_C_CA PF18599.1 CDJ63940.1 - 8.1 5.7 9.9 9.2 5.5 9.9 1.0 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases R_equi_Vir PF05526.11 CDJ63940.1 - 8.2 6.2 7.4 9 6.1 7.4 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RskA PF10099.9 CDJ63941.1 - 0.0023 18.3 12.0 0.0023 18.3 12.0 6.6 3 2 1 4 4 4 1 Anti-sigma-K factor rskA Borrelia_P83 PF05262.11 CDJ63942.1 - 0.0011 17.5 5.7 0.0011 17.5 5.7 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein TFIIA PF03153.13 CDJ63942.1 - 0.0046 17.0 32.0 0.0055 16.8 32.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MecA PF05389.12 CDJ63942.1 - 0.0081 15.8 5.9 0.01 15.5 5.9 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) TERB2 PF15101.6 CDJ63942.1 - 0.016 15.2 14.8 0.022 14.8 14.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 LON_substr_bdg PF02190.16 CDJ63942.1 - 0.019 14.8 3.0 0.026 14.4 3.0 1.3 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain RRP36 PF06102.12 CDJ63942.1 - 0.023 14.6 18.7 0.038 13.9 18.7 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF2992 PF11208.8 CDJ63942.1 - 0.024 14.8 17.8 0.04 14.2 17.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF2347 PF09804.9 CDJ63942.1 - 0.033 13.8 7.0 0.043 13.4 7.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) LMBR1 PF04791.16 CDJ63942.1 - 0.045 12.7 5.9 0.051 12.5 5.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 CDJ63942.1 - 0.055 12.1 10.0 0.065 11.8 10.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Suf PF05843.14 CDJ63942.1 - 0.091 12.7 13.0 0.13 12.2 13.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Exonuc_VII_L PF02601.15 CDJ63942.1 - 0.1 12.1 17.0 0.12 11.9 17.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SpoIIP PF07454.11 CDJ63942.1 - 0.11 11.9 10.1 0.14 11.6 10.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ABC2_membrane_3 PF12698.7 CDJ63942.1 - 0.14 11.2 5.9 0.19 10.8 5.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein HemX PF04375.14 CDJ63942.1 - 0.15 11.3 37.4 0.21 10.9 37.4 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Neur_chan_memb PF02932.16 CDJ63942.1 - 0.16 12.0 5.7 0.19 11.7 5.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cyclin_C PF02984.19 CDJ63942.1 - 0.16 12.0 7.8 0.23 11.5 7.8 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain Ctr PF04145.15 CDJ63942.1 - 0.24 12.0 3.8 0.33 11.6 3.8 1.3 1 0 0 1 1 1 0 Ctr copper transporter family EOS1 PF12326.8 CDJ63942.1 - 0.24 11.3 2.5 0.31 10.9 2.5 1.2 1 0 0 1 1 1 0 N-glycosylation protein BPL_N PF09825.9 CDJ63942.1 - 0.32 10.0 6.3 0.39 9.7 6.3 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal EIIBC-GUT_N PF03612.14 CDJ63942.1 - 0.35 10.6 8.7 0.53 10.0 8.7 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Band_3_cyto PF07565.13 CDJ63942.1 - 0.38 10.5 10.6 0.61 9.8 10.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.17 CDJ63942.1 - 0.41 10.8 11.6 0.55 10.3 11.6 1.1 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.6 CDJ63942.1 - 0.56 9.5 17.5 0.76 9.1 17.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pex14_N PF04695.13 CDJ63942.1 - 0.82 10.3 20.0 1.1 9.9 20.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4746 PF15928.5 CDJ63942.1 - 0.86 9.0 6.7 1.2 8.5 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Med15 PF09606.10 CDJ63942.1 - 1 8.0 36.9 1.2 7.7 36.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_U57 PF05582.12 CDJ63942.1 - 1.2 8.4 10.8 1.5 8.0 10.8 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Folliculin PF11704.8 CDJ63942.1 - 1.2 8.9 10.5 1.8 8.4 10.5 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport V_ATPase_I PF01496.19 CDJ63942.1 - 1.3 6.9 13.7 1.6 6.6 13.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.6 CDJ63942.1 - 1.3 9.0 8.5 1.8 8.5 8.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CLN3 PF02487.17 CDJ63942.1 - 1.5 7.8 10.1 2 7.4 10.1 1.1 1 0 0 1 1 1 0 CLN3 protein MCU PF04678.13 CDJ63942.1 - 2.3 8.3 10.0 3.1 7.8 10.0 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Presenilin PF01080.17 CDJ63942.1 - 2.5 6.8 14.9 3.2 6.4 14.9 1.1 1 0 0 1 1 1 0 Presenilin Hydin_ADK PF17213.3 CDJ63942.1 - 2.8 8.2 9.1 4.3 7.6 9.1 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain EPL1 PF10513.9 CDJ63942.1 - 3.5 8.0 13.8 31 4.9 15.2 1.8 2 0 0 2 2 2 0 Enhancer of polycomb-like Anp1 PF03452.14 CDJ63942.1 - 3.7 6.9 12.0 5 6.4 12.0 1.1 1 0 0 1 1 1 0 Anp1 Membralin PF09746.9 CDJ63942.1 - 3.8 6.5 7.7 4.9 6.1 7.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein Asparaginase_2 PF01112.18 CDJ63942.1 - 4.6 6.2 7.3 5.4 5.9 7.3 1.1 1 0 0 1 1 1 0 Asparaginase Connexin PF00029.19 CDJ63942.1 - 4.8 6.9 9.9 6.7 6.4 9.9 1.2 1 0 0 1 1 1 0 Connexin FAD-SLDH PF12318.8 CDJ63942.1 - 5.1 7.1 16.4 7.8 6.5 16.4 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase eIF-3_zeta PF05091.12 CDJ63942.1 - 5.1 5.9 18.7 6.5 5.6 18.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Het-C PF07217.11 CDJ63942.1 - 5.7 5.3 12.1 7.5 4.9 12.1 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C ALMT PF11744.8 CDJ63942.1 - 5.8 5.6 11.9 7.3 5.3 11.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 CDJ63942.1 - 6.4 5.9 5.6 8.5 5.5 5.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MRP-S27 PF10037.9 CDJ63942.1 - 6.6 5.5 20.1 8.3 5.2 20.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Serinc PF03348.15 CDJ63942.1 - 7.1 5.4 7.7 8.7 5.1 7.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ndc1_Nup PF09531.10 CDJ63942.1 - 7.1 5.2 12.2 9 4.8 12.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2828 PF11443.8 CDJ63942.1 - 7.9 4.4 13.8 10 4.1 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) HI0933_like PF03486.14 CDJ63942.1 - 8.6 4.9 14.7 12 4.5 14.7 1.1 1 0 0 1 1 1 0 HI0933-like protein Peroxin-13_N PF04088.13 CDJ63942.1 - 10 6.4 11.0 18 5.6 11.0 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Spt20 PF12090.8 CDJ63943.1 - 0.0014 18.3 8.0 0.0014 18.3 8.0 1.0 1 0 0 1 1 1 1 Spt20 family DUF2927 PF11150.8 CDJ63943.1 - 0.0044 17.1 7.0 0.0045 17.1 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2927) DUF3138 PF11336.8 CDJ63943.1 - 0.069 11.8 20.9 0.079 11.6 20.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2722 PF10846.8 CDJ63943.1 - 0.24 10.3 8.2 0.24 10.3 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BAT2_N PF07001.11 CDJ63943.1 - 0.25 11.8 9.0 0.29 11.6 9.0 1.0 1 0 0 1 1 1 0 BAT2 N-terminus CCDC53 PF10152.9 CDJ63943.1 - 0.4 11.1 7.4 0.46 10.9 7.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RLL PF10036.9 CDJ63943.1 - 0.45 10.3 9.3 0.53 10.1 9.3 1.0 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein TFIIA PF03153.13 CDJ63943.1 - 0.73 9.8 15.0 0.88 9.5 15.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2368 PF10166.9 CDJ63943.1 - 0.88 9.2 9.6 1.1 8.9 9.6 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) DUF3306 PF11748.8 CDJ63943.1 - 0.97 10.3 10.6 1.4 9.8 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) RIFIN PF02009.16 CDJ63943.1 - 1 9.2 7.5 1.2 9.0 7.5 1.1 1 0 0 1 1 1 0 Rifin FTZ PF03867.14 CDJ63943.1 - 2.3 7.7 12.8 2.8 7.4 12.8 1.0 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region DLIC PF05783.11 CDJ63943.1 - 4.6 6.0 5.8 5 5.8 5.8 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Med15 PF09606.10 CDJ63943.1 - 7.1 5.2 16.8 7.9 5.0 16.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RINGv PF12906.7 CDJ63944.1 - 9.4e-13 48.1 5.8 2.1e-12 47.0 5.8 1.7 1 1 0 1 1 1 1 RING-variant domain DUF5621 PF18532.1 CDJ63944.1 - 0.005 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5621) zf-RING_2 PF13639.6 CDJ63944.1 - 0.0077 16.6 1.7 0.0077 16.6 1.7 2.1 3 0 0 3 3 3 1 Ring finger domain FANCL_C PF11793.8 CDJ63944.1 - 0.03 14.5 1.4 0.062 13.5 1.4 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Spt20 PF12090.8 CDJ63945.1 - 0.0039 16.8 7.1 0.0041 16.8 7.1 1.0 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ63945.1 - 0.012 14.6 2.3 0.012 14.6 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF3824 PF12868.7 CDJ63945.1 - 0.034 14.8 2.9 0.034 14.8 2.9 3.1 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) K_channel_TID PF07941.11 CDJ63945.1 - 0.043 14.3 13.2 0.043 14.3 13.2 3.9 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain TFIIA PF03153.13 CDJ63945.1 - 0.18 11.8 14.1 0.25 11.3 14.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EIIBC-GUT_N PF03612.14 CDJ63945.1 - 1 9.1 5.9 0.21 11.3 2.2 1.7 1 1 1 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2207 PF09972.9 CDJ63946.1 - 1.1e-05 24.5 0.0 0.092 11.5 0.0 3.3 3 0 0 3 3 3 2 Predicted membrane protein (DUF2207) K_channel_TID PF07941.11 CDJ63946.1 - 7.1e-05 23.2 6.6 7.1e-05 23.2 6.6 15.3 11 2 1 12 12 12 2 Potassium channel Kv1.4 tandem inactivation domain FmiP_Thoc5 PF09766.9 CDJ63946.1 - 0.001 18.5 2.2 0.001 18.5 2.2 5.7 5 1 0 5 5 5 1 Fms-interacting protein/Thoc5 Orf78 PF06024.12 CDJ63946.1 - 0.0027 18.0 0.5 0.0027 18.0 0.5 6.7 6 1 1 7 7 7 1 Orf78 (ac78) DUF4770 PF15994.5 CDJ63946.1 - 0.0041 17.4 5.5 0.0041 17.4 5.5 5.1 5 1 0 5 5 5 1 Domain of unknown function (DUF4770) DUF3464 PF11947.8 CDJ63946.1 - 0.018 14.8 1.1 0.018 14.8 1.1 6.4 6 1 1 7 7 7 0 Photosynthesis affected mutant 68 Connexin PF00029.19 CDJ63946.1 - 0.027 14.3 0.7 0.027 14.3 0.7 4.7 4 1 0 4 4 4 0 Connexin LMBR1 PF04791.16 CDJ63946.1 - 0.033 13.1 9.8 0.032 13.2 0.5 2.5 2 0 0 2 2 2 0 LMBR1-like membrane protein PBP1_TM PF14812.6 CDJ63946.1 - 0.11 12.9 0.1 0.11 12.9 0.1 3.0 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DEAD PF00270.29 CDJ63947.1 - 5.4e-39 133.7 0.1 3e-38 131.3 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ63947.1 - 3e-27 95.1 0.0 1.1e-25 90.1 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ63947.1 - 0.00045 20.3 0.0 0.00045 20.3 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ63947.1 - 0.026 14.8 4.1 0.03 14.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain SUIM_assoc PF16619.5 CDJ63947.1 - 0.042 13.9 0.1 0.042 13.9 0.1 6.4 4 2 2 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 Pox_A32 PF04665.12 CDJ63947.1 - 0.22 10.9 0.0 0.44 10.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RRM_5 PF13893.6 CDJ63948.1 - 2.7e-24 85.1 0.0 1.1e-14 54.1 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CDJ63948.1 - 8.4e-19 67.2 0.9 1.2e-05 25.0 0.4 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CDJ63948.1 - 4.3e-09 36.5 0.1 0.00015 21.9 0.1 3.4 3 0 0 3 3 3 2 RRM-like domain GT87 PF09594.10 CDJ63949.1 - 0.003 17.3 0.6 0.0032 17.2 0.6 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 87 PP2C_2 PF13672.6 CDJ63949.1 - 0.0067 16.1 3.8 0.0081 15.8 3.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C DUF4179 PF13786.6 CDJ63949.1 - 0.035 14.6 3.1 0.042 14.3 3.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Abhydrolase_9_N PF15420.6 CDJ63949.1 - 0.065 13.2 6.8 0.074 13.1 6.8 1.0 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF2232 PF09991.9 CDJ63949.1 - 0.23 10.6 3.4 0.27 10.4 3.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Ribosomal_60s PF00428.19 CDJ63949.1 - 1.2 9.7 12.5 1.8 9.2 12.5 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein LCIB_C_CA PF18599.1 CDJ63949.1 - 1.4 8.2 6.2 1.5 8.1 6.2 1.1 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases TFIIA PF03153.13 CDJ63949.1 - 2.6 7.9 27.0 3.1 7.7 27.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.9 CDJ63950.1 - 0.0093 14.9 27.0 0.012 14.5 27.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Retinal PF15449.6 CDJ63950.1 - 0.41 8.4 38.3 0.48 8.1 38.3 1.0 1 0 0 1 1 1 0 Retinal protein Hamartin PF04388.12 CDJ63950.1 - 2.7 6.6 22.7 3.9 6.0 22.7 1.2 1 0 0 1 1 1 0 Hamartin protein DUF4551 PF15087.6 CDJ63950.1 - 3.5 6.3 25.4 4.5 6.0 25.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF966 PF06136.13 CDJ63950.1 - 3.8 7.1 27.1 5 6.7 27.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DLIC PF05783.11 CDJ63950.1 - 5.4 5.7 15.1 7.2 5.3 15.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RAP1 PF07218.11 CDJ63950.1 - 6.6 4.9 6.8 7.9 4.6 6.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SUIM_assoc PF16619.5 CDJ63952.1 - 0.0036 17.3 6.8 0.0036 17.3 6.8 3.0 3 2 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Sld7_C PF18596.1 CDJ63952.1 - 0.1 12.8 2.0 0.49 10.6 1.1 2.3 2 0 0 2 2 2 0 Sld7 C-terminal domain Borrelia_P83 PF05262.11 CDJ63952.1 - 0.11 10.9 22.8 0.16 10.4 16.6 2.2 2 0 0 2 2 2 0 Borrelia P83/100 protein FolB PF02152.18 CDJ63953.1 - 0.13 12.8 0.8 0.58 10.7 0.0 2.3 2 1 0 2 2 2 0 Dihydroneopterin aldolase TFIIA PF03153.13 CDJ63953.1 - 0.62 10.0 30.7 0.8 9.6 30.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HI0933_like PF03486.14 CDJ63953.1 - 0.75 8.4 6.1 1.2 7.8 6.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FapA PF03961.13 CDJ63953.1 - 7.5 5.0 12.8 0.22 10.1 0.3 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF4667 PF15700.5 CDJ63955.1 - 0.0062 16.7 0.0 0.0065 16.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) DUF5134 PF17197.4 CDJ63955.1 - 0.32 10.9 9.3 0.54 10.2 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) RskA PF10099.9 CDJ63955.1 - 5.5 7.2 29.9 67 3.7 29.6 2.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RAB3GAP2_C PF14656.6 CDJ63956.1 - 0.0082 14.4 3.7 0.012 13.9 3.7 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus Presenilin PF01080.17 CDJ63956.1 - 0.011 14.6 5.1 0.017 13.9 5.1 1.2 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CDJ63956.1 - 0.12 12.6 4.1 0.3 11.3 4.1 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal IDO PF01231.18 CDJ63956.1 - 0.27 10.0 6.7 0.46 9.2 6.7 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase DUF4228 PF14009.6 CDJ63956.1 - 0.45 10.9 5.9 5.6 7.3 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Velvet PF11754.8 CDJ63956.1 - 0.49 10.3 13.6 0.06 13.3 7.7 2.3 3 0 0 3 3 3 0 Velvet factor eIF-3_zeta PF05091.12 CDJ63956.1 - 0.57 9.1 12.8 0.86 8.5 12.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1980 PF09323.10 CDJ63956.1 - 0.74 9.7 4.8 1.4 8.8 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DDHD PF02862.17 CDJ63956.1 - 0.87 9.7 9.2 0.094 12.9 3.6 2.1 3 0 0 3 3 3 0 DDHD domain Connexin PF00029.19 CDJ63956.1 - 1 9.0 5.2 1.5 8.5 5.2 1.1 1 0 0 1 1 1 0 Connexin G0-G1_switch_2 PF15103.6 CDJ63956.1 - 1.2 9.6 4.3 2.2 8.7 4.3 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 Neur_chan_memb PF02932.16 CDJ63956.1 - 1.5 8.9 7.1 2.9 7.9 7.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 CDJ63956.1 - 1.6 6.9 22.5 3.1 6.0 22.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EIIBC-GUT_N PF03612.14 CDJ63956.1 - 1.8 8.2 8.2 3.3 7.4 8.2 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TCP PF03634.13 CDJ63956.1 - 1.9 9.1 11.8 0.66 10.5 4.9 2.8 3 0 0 3 3 3 0 TCP family transcription factor SpoIIP PF07454.11 CDJ63956.1 - 1.9 7.9 12.0 2.9 7.3 12.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Folliculin PF11704.8 CDJ63956.1 - 2 8.3 10.5 4.6 7.1 10.5 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport NARP1 PF12569.8 CDJ63956.1 - 2.3 7.0 8.8 3.5 6.4 8.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Tim54 PF11711.8 CDJ63956.1 - 2.6 6.7 8.5 4.5 6.0 8.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2828 PF11443.8 CDJ63956.1 - 2.7 6.0 7.8 3.8 5.5 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CobT PF06213.12 CDJ63956.1 - 2.9 7.2 21.9 7.7 5.8 21.9 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 CDJ63956.1 - 2.9 7.6 9.0 4.5 7.0 9.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ63956.1 - 3.1 6.5 4.5 4.5 6.0 4.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Het-C PF07217.11 CDJ63956.1 - 3.8 5.9 5.3 6.2 5.2 5.3 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C CCDC53 PF10152.9 CDJ63956.1 - 3.8 7.9 20.5 3.6 8.0 15.8 2.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex EOS1 PF12326.8 CDJ63956.1 - 4.6 7.1 4.4 8.1 6.3 4.4 1.3 1 0 0 1 1 1 0 N-glycosylation protein MID_MedPIWI PF18296.1 CDJ63956.1 - 5.3 6.8 18.0 17 5.1 0.2 2.2 2 0 0 2 2 2 0 MID domain of medPIWI Nucleo_P87 PF07267.11 CDJ63956.1 - 5.4 5.7 11.9 9.1 5.0 11.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Peptidase_M14 PF00246.24 CDJ63957.1 - 1.1e-14 54.9 0.0 1.4e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase EarP PF10093.9 CDJ63957.1 - 0.03 13.4 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP RAB3GAP2_N PF14655.6 CDJ63957.1 - 0.075 12.3 0.1 0.095 11.9 0.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIA PF03153.13 CDJ63957.1 - 0.11 12.5 6.9 0.13 12.2 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ63957.1 - 0.27 10.8 8.7 0.43 10.2 8.7 1.3 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ63957.1 - 1 8.2 6.5 1.3 7.8 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) VPS13_C PF16909.5 CDJ63958.1 - 8.8e-17 61.4 0.0 1.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CDJ63958.1 - 2.2e-13 50.2 0.0 1.5e-09 37.6 0.0 2.7 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 CDJ63962.1 - 4.8e-07 29.8 0.0 4.1e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal ANAPC4_WD40 PF12894.7 CDJ63963.1 - 0.0016 18.7 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_12 PF13424.6 CDJ63964.1 - 0.007 16.6 0.7 1.2 9.5 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TRC8_N PF13705.6 CDJ63964.1 - 0.051 12.5 0.0 0.063 12.2 0.0 1.1 1 0 0 1 1 1 0 TRC8 N-terminal domain Gp_dh_C PF02800.20 CDJ63967.1 - 3.1e-67 225.1 0.0 4.3e-67 224.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CDJ63967.1 - 2.7e-38 130.4 0.0 6.1e-38 129.2 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CDJ63967.1 - 0.025 14.7 0.1 0.097 12.8 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RT_RNaseH PF17917.1 CDJ63968.1 - 6.2e-26 90.7 0.0 9.1e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ63968.1 - 2.6e-24 85.2 0.0 4.1e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ63968.1 - 0.0081 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Cyclin PF08613.11 CDJ63969.1 - 1.3e-06 28.8 1.5 5.4e-05 23.6 0.0 2.9 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 CDJ63969.1 - 0.022 14.5 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain ATP-synt_10 PF05176.14 CDJ63970.1 - 0.0022 17.3 0.0 0.4 9.9 0.0 2.1 2 0 0 2 2 2 2 ATP10 protein tRNA-synt_His PF13393.6 CDJ63971.1 - 1.3e-14 54.2 1.1 3.8e-07 29.7 0.1 3.6 3 1 1 4 4 4 2 Histidyl-tRNA synthetase Ribosomal_L7Ae PF01248.26 CDJ63972.1 - 4.6e-23 80.8 1.6 8.6e-23 79.9 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CDJ63972.1 - 0.029 14.4 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 Metallophos_2 PF12850.7 CDJ63973.1 - 2.1e-19 70.3 0.0 2.6e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CDJ63973.1 - 0.00033 21.2 2.4 0.0062 17.1 0.6 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase CHCH PF06747.13 CDJ63974.1 - 6e-05 23.1 2.6 0.00012 22.2 2.6 1.5 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CDJ63974.1 - 2.1 8.4 6.0 0.4 10.7 1.2 1.9 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pex14_N PF04695.13 CDJ63975.1 - 0.014 16.0 11.6 0.026 15.2 11.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-5_eIF-2B PF01873.17 CDJ63976.1 - 7.3e-35 119.4 0.4 3.6e-34 117.1 0.0 2.2 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 CDJ63976.1 - 3.2e-15 56.0 0.2 3.2e-15 56.0 0.2 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Nop14 PF04147.12 CDJ63976.1 - 0.24 9.6 21.1 0.33 9.1 21.1 1.1 1 0 0 1 1 1 0 Nop14-like family Ndc1_Nup PF09531.10 CDJ63976.1 - 0.28 9.8 2.1 0.32 9.6 2.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF-3c_N PF05470.12 CDJ63976.1 - 0.66 8.2 13.8 0.86 7.8 13.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4551 PF15087.6 CDJ63976.1 - 3.3 6.5 6.5 4.1 6.1 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SRP-alpha_N PF04086.13 CDJ63976.1 - 3.5 7.5 26.7 2.6 7.9 24.3 1.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal ALMT PF11744.8 CDJ63976.1 - 3.7 6.3 7.7 5.4 5.7 7.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CDC45 PF02724.14 CDJ63976.1 - 3.8 5.7 17.1 5.3 5.2 17.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 CDJ63976.1 - 5.9 5.8 8.1 8.9 5.2 8.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 CDJ63976.1 - 6.7 5.4 12.2 8.6 5.0 12.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1772 PF08592.11 CDJ63977.1 - 0.35 11.2 9.1 0.29 11.4 4.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) EAGR_box PF16713.5 CDJ63978.1 - 0.00095 18.8 5.6 0.00095 18.8 5.6 4.2 4 0 0 4 4 4 3 Enriched in aromatic and glycine Residues box TFIIA PF03153.13 CDJ63979.1 - 0.0062 16.6 12.2 0.0061 16.6 12.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4692 PF15763.5 CDJ63979.1 - 0.011 16.2 8.1 0.011 16.2 8.1 1.5 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) NPR1_interact PF15699.5 CDJ63979.1 - 0.47 11.1 4.8 0.71 10.5 4.8 1.3 1 0 0 1 1 1 0 NPR1 interacting DUF755 PF05501.11 CDJ63979.1 - 0.82 10.0 30.4 0.15 12.4 20.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SPX PF03105.19 CDJ63979.1 - 4.4 7.1 15.2 5.8 6.7 15.2 1.4 1 0 0 1 1 1 0 SPX domain ANAPC_CDC26 PF10471.9 CDJ63979.1 - 9 7.2 25.0 0.46 11.4 10.3 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Activator_LAG-3 PF11498.8 CDJ63980.1 - 0.0003 19.9 7.8 0.0003 19.9 7.8 6.3 7 0 0 7 7 7 2 Transcriptional activator LAG-3 SUIM_assoc PF16619.5 CDJ63982.1 - 0.023 14.8 6.8 0.023 14.8 6.8 8.4 6 1 1 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 Spore_YhcN_YlaJ PF09580.10 CDJ63982.1 - 0.27 11.3 23.2 1.3 9.1 0.2 3.5 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) OAD_gamma PF04277.13 CDJ63982.1 - 2.8 8.6 0.0 2.8 8.6 0.0 6.1 5 3 0 5 5 5 0 Oxaloacetate decarboxylase, gamma chain LRR_8 PF13855.6 CDJ63983.1 - 7.4e-08 32.0 18.5 0.00012 21.7 7.0 3.3 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CDJ63983.1 - 2.4e-06 27.8 14.4 0.025 15.0 1.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) Spt20 PF12090.8 CDJ63984.1 - 3.7e-07 30.0 48.0 0.00076 19.2 33.4 2.3 2 0 0 2 2 2 2 Spt20 family PRP1_N PF06424.12 CDJ63984.1 - 0.003 18.0 4.7 0.003 18.0 4.7 2.2 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal PBP1_TM PF14812.6 CDJ63984.1 - 0.0053 17.1 0.8 0.0053 17.1 0.8 2.0 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal EPL1 PF10513.9 CDJ63984.1 - 0.011 16.1 17.1 0.18 12.2 10.5 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Pinin_SDK_memA PF04696.13 CDJ63984.1 - 0.023 14.7 34.5 0.13 12.3 4.0 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region NST1 PF13945.6 CDJ63984.1 - 0.058 13.5 25.3 0.85 9.7 0.7 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator SpoIIP PF07454.11 CDJ63984.1 - 0.062 12.7 15.7 0.11 11.9 9.9 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 CDJ63984.1 - 0.071 13.2 14.8 0.34 11.0 9.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF702 PF05142.12 CDJ63984.1 - 0.097 13.1 23.8 0.38 11.2 12.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Band_3_cyto PF07565.13 CDJ63984.1 - 0.14 12.0 15.4 0.28 11.0 8.4 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4834 PF16118.5 CDJ63984.1 - 0.14 13.1 26.6 2 9.4 16.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) STAC2_u1 PF16664.5 CDJ63984.1 - 0.14 12.6 9.6 0.91 10.0 4.5 2.3 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 CDC45 PF02724.14 CDJ63984.1 - 0.16 10.2 9.1 0.013 13.8 2.9 1.9 2 0 0 2 2 2 0 CDC45-like protein Apc15p PF05841.11 CDJ63984.1 - 0.2 12.5 28.6 0.73 10.6 17.5 2.5 2 0 0 2 2 2 0 Apc15p protein eIF-3_zeta PF05091.12 CDJ63984.1 - 0.21 10.5 26.3 0.022 13.7 14.7 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3807 PF12720.7 CDJ63984.1 - 0.28 11.4 26.5 0.73 10.1 16.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Eapp_C PF10238.9 CDJ63984.1 - 0.35 10.9 19.6 0.29 11.2 9.9 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein NPR3 PF03666.13 CDJ63984.1 - 0.37 9.5 13.2 0.058 12.2 6.6 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 RPA43_OB PF17875.1 CDJ63984.1 - 0.45 11.2 12.3 1.2 9.8 6.4 2.4 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I EFTUD2 PF16004.5 CDJ63984.1 - 0.52 10.9 20.2 5.6 7.6 14.5 2.3 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Tim54 PF11711.8 CDJ63984.1 - 0.55 8.9 14.3 0.73 8.6 9.3 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF3371 PF11851.8 CDJ63984.1 - 0.58 11.2 23.9 3.6 8.7 14.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) RPN2_C PF18004.1 CDJ63984.1 - 0.59 10.0 15.2 0.081 12.8 6.3 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Membralin PF09746.9 CDJ63984.1 - 0.68 8.9 7.3 0.12 11.4 2.6 1.8 2 0 0 2 2 2 0 Tumour-associated protein PEX11 PF05648.14 CDJ63984.1 - 0.73 9.2 10.0 0.55 9.7 4.3 2.2 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DUF2828 PF11443.8 CDJ63984.1 - 0.82 7.7 16.1 0.22 9.6 9.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Lin-8 PF03353.15 CDJ63984.1 - 0.85 9.1 21.6 1.3 8.5 12.7 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Connexin PF00029.19 CDJ63984.1 - 0.89 9.3 12.0 0.25 11.1 5.7 2.0 2 0 0 2 2 2 0 Connexin FAM150 PF15129.6 CDJ63984.1 - 0.9 9.7 17.7 0.14 12.3 8.4 2.2 2 0 0 2 2 2 0 FAM150 family MecA PF05389.12 CDJ63984.1 - 0.94 9.1 13.3 0.22 11.1 5.0 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) XAP5 PF04921.14 CDJ63984.1 - 0.97 9.2 11.0 1 9.1 5.6 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator Slu7 PF11708.8 CDJ63984.1 - 1 9.0 24.5 2.7 7.7 1.3 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor TCP PF03634.13 CDJ63984.1 - 1.1 9.8 22.9 0.63 10.6 14.2 2.2 2 0 0 2 2 2 0 TCP family transcription factor SID-1_RNA_chan PF13965.6 CDJ63984.1 - 1.1 7.6 5.6 0.061 11.7 0.5 1.5 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 PRC2_HTH_1 PF18118.1 CDJ63984.1 - 1.2 10.0 13.0 19 6.2 0.1 2.3 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain MDM10 PF12519.8 CDJ63984.1 - 1.3 7.8 12.1 0.55 9.0 6.9 2.0 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 DUF5327 PF17261.2 CDJ63984.1 - 1.3 9.8 30.6 1.9 9.3 18.7 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF3464 PF11947.8 CDJ63984.1 - 1.4 8.7 21.9 0.15 11.8 10.0 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 HNOBA PF07701.14 CDJ63984.1 - 1.9 7.9 11.8 1.2 8.5 6.2 2.1 2 0 0 2 2 2 0 Heme NO binding associated Peroxin-13_N PF04088.13 CDJ63984.1 - 2 8.7 10.1 0.79 10.0 3.0 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Mlh1_C PF16413.5 CDJ63984.1 - 2.2 7.6 11.0 0.53 9.6 4.0 2.1 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus FHIPEP PF00771.20 CDJ63984.1 - 2.4 6.5 12.1 0.31 9.5 4.1 2.1 2 0 0 2 2 2 0 FHIPEP family Pal1 PF08316.11 CDJ63984.1 - 2.5 8.8 11.1 1.7 9.4 6.0 2.2 2 0 0 2 2 2 0 Pal1 cell morphology protein DUF3408 PF11888.8 CDJ63984.1 - 3 8.0 20.1 6.2 7.0 12.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Bul1_N PF04425.12 CDJ63984.1 - 3.1 6.5 12.8 0.21 10.3 6.1 1.9 2 0 0 2 2 2 0 Bul1 N terminus NARP1 PF12569.8 CDJ63984.1 - 3.7 6.4 20.7 0.073 12.0 10.5 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 MPM1 PF17234.2 CDJ63984.1 - 3.7 7.8 24.3 4.7 7.4 0.7 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Rtf2 PF04641.12 CDJ63984.1 - 3.8 6.8 16.9 0.72 9.2 7.2 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Itfg2 PF15907.5 CDJ63984.1 - 4.4 6.2 11.1 0.64 9.0 5.2 1.9 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 DUF4770 PF15994.5 CDJ63984.1 - 5 7.3 23.2 2.5 8.3 13.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) TERB2 PF15101.6 CDJ63984.1 - 6 6.9 33.5 5.6 7.0 22.2 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 RAG1_imp_bd PF12560.8 CDJ63984.1 - 6.1 6.3 17.2 0.63 9.5 10.0 2.0 2 0 0 2 2 2 0 RAG1 importin binding FAM176 PF14851.6 CDJ63984.1 - 6.7 6.4 12.8 4.3 7.0 8.0 2.2 2 0 0 2 2 2 0 FAM176 family G0-G1_switch_2 PF15103.6 CDJ63984.1 - 6.9 7.2 16.6 14 6.2 9.9 2.5 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF4449 PF14613.6 CDJ63984.1 - 7.5 6.6 19.2 6.8 6.8 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) DUF4820 PF16091.5 CDJ63984.1 - 8.6 5.7 17.8 1.8 7.9 9.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) CSG2 PF16965.5 CDJ63984.1 - 8.6 5.2 8.7 0.35 9.8 2.2 1.7 2 0 0 2 2 2 0 Ceramide synthase regulator DUF853 PF05872.12 CDJ63984.1 - 8.7 4.8 19.7 3 6.3 10.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Rxt3 PF08642.10 CDJ63984.1 - 8.8 7.1 12.7 6.8 7.5 5.8 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 zf-MYND PF01753.18 CDJ63986.1 - 4.4e-12 45.9 6.8 1.7e-11 44.0 6.8 2.0 1 0 0 1 1 1 1 MYND finger SET PF00856.28 CDJ63986.1 - 1.4e-08 35.3 1.9 3.7e-07 30.7 0.4 2.7 2 1 0 2 2 2 1 SET domain SPX PF03105.19 CDJ63986.1 - 0.18 11.7 1.6 0.24 11.3 1.6 1.2 1 0 0 1 1 1 0 SPX domain DUF4908 PF16252.5 CDJ63986.1 - 0.73 9.3 4.6 1.5 8.3 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4908) Apt1 PF10351.9 CDJ63986.1 - 3.3 6.5 4.6 5.2 5.8 4.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribophorin_I PF04597.14 CDJ63987.1 - 2.7e-62 211.4 0.0 3.8e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Ribophorin I DUF4618 PF15397.6 CDJ63987.1 - 0.032 13.6 0.3 0.063 12.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF1488 PF07369.11 CDJ63987.1 - 0.06 13.3 1.8 0.22 11.5 0.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1488) zf-LSD1 PF06943.12 CDJ63987.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 LSD1 zinc finger SKA2 PF16740.5 CDJ63988.1 - 1.9e-05 24.4 1.0 3.1e-05 23.7 1.0 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 EccE PF11203.8 CDJ63988.1 - 1.4 9.3 5.0 2.3 8.6 4.1 2.0 1 1 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE Spt20 PF12090.8 CDJ63989.1 - 0.0013 18.4 9.8 0.0019 17.8 9.8 1.3 1 0 0 1 1 1 1 Spt20 family CRT-like PF08627.10 CDJ63989.1 - 0.002 17.1 4.3 0.004 16.1 3.6 1.9 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like DUF2052 PF09747.9 CDJ63989.1 - 0.017 15.2 2.4 0.023 14.8 2.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) MDFI PF15316.6 CDJ63989.1 - 0.15 12.2 2.9 0.21 11.7 2.9 1.2 1 0 0 1 1 1 0 MyoD family inhibitor GTA_holin_3TM PF11351.8 CDJ63989.1 - 0.2 12.2 5.8 0.056 14.0 1.3 2.5 1 1 1 2 2 2 0 Holin of 3TMs, for gene-transfer release DUF572 PF04502.13 CDJ63989.1 - 0.26 10.8 6.0 0.41 10.2 6.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SR-25 PF10500.9 CDJ63989.1 - 0.4 10.3 10.7 0.57 9.8 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ63989.1 - 0.52 10.3 18.3 0.64 9.9 18.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Miga PF10265.9 CDJ63989.1 - 1.2 8.0 8.1 1.6 7.6 8.1 1.1 1 0 0 1 1 1 0 Mitoguardin GREB1 PF15782.5 CDJ63989.1 - 4.2 4.3 9.3 5.4 4.0 9.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF755 PF05501.11 CDJ63989.1 - 4.4 7.6 24.4 8.1 6.7 24.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF755) DUF1700 PF08006.11 CDJ63989.1 - 8 6.0 10.2 54 3.3 8.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) SR-25 PF10500.9 CDJ63990.1 - 0.0022 17.6 7.9 0.0031 17.2 7.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SelP_N PF04592.14 CDJ63990.1 - 0.14 11.5 3.5 0.15 11.5 3.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Spt20 PF12090.8 CDJ63990.1 - 0.89 9.1 7.9 1 8.9 7.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF4366 PF14283.6 CDJ63990.1 - 1.8 8.6 5.6 1.9 8.6 4.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) FTZ PF03867.14 CDJ63990.1 - 2.7 7.5 14.0 3 7.3 14.0 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region SR-25 PF10500.9 CDJ63991.1 - 3.2 7.3 31.2 4.3 6.9 31.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MecA PF05389.12 CDJ63993.1 - 0.0022 17.7 5.0 0.0023 17.6 5.0 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) ALF PF03752.13 CDJ63993.1 - 0.0056 16.6 0.8 4 7.5 0.0 2.8 2 1 1 3 3 3 1 Short repeats of unknown function TFIIA PF03153.13 CDJ63993.1 - 0.013 15.5 27.5 0.014 15.4 27.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4746 PF15928.5 CDJ63993.1 - 0.022 14.2 5.7 0.023 14.1 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pex14_N PF04695.13 CDJ63993.1 - 0.026 15.2 12.8 0.031 14.9 12.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ63993.1 - 0.03 14.3 11.7 0.032 14.2 11.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.17 CDJ63993.1 - 0.096 12.8 8.2 0.11 12.7 8.2 1.1 1 0 0 1 1 1 0 DDHD domain Peptidase_S49_N PF08496.10 CDJ63993.1 - 0.16 12.0 12.1 0.2 11.7 12.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CobT PF06213.12 CDJ63993.1 - 0.25 10.7 15.3 0.27 10.6 15.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4834 PF16118.5 CDJ63993.1 - 0.3 12.1 10.4 0.44 11.5 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AAA_23 PF13476.6 CDJ63993.1 - 0.32 11.5 16.5 0.36 11.3 16.5 1.1 1 0 0 1 1 1 0 AAA domain Orf78 PF06024.12 CDJ63993.1 - 0.4 11.0 4.8 0.63 10.4 4.8 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Presenilin PF01080.17 CDJ63993.1 - 0.4 9.4 10.2 0.41 9.4 10.2 1.1 1 0 0 1 1 1 0 Presenilin Folliculin PF11704.8 CDJ63993.1 - 0.55 10.1 9.4 0.82 9.5 9.4 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport EOS1 PF12326.8 CDJ63993.1 - 0.55 10.1 3.3 0.56 10.1 3.3 1.2 1 0 0 1 1 1 0 N-glycosylation protein Connexin PF00029.19 CDJ63993.1 - 0.71 9.6 6.6 0.84 9.4 6.6 1.1 1 0 0 1 1 1 0 Connexin DUF4175 PF13779.6 CDJ63993.1 - 0.74 7.7 26.9 0.73 7.7 26.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) LIM_bind PF01803.16 CDJ63993.1 - 0.87 9.1 13.1 1.3 8.5 13.1 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Exonuc_VII_L PF02601.15 CDJ63993.1 - 0.94 9.0 13.3 1 8.8 13.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 CDJ63993.1 - 1.4 7.7 10.2 1.4 7.7 10.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SpoIIP PF07454.11 CDJ63993.1 - 1.4 8.3 11.4 1.8 8.0 11.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FAM60A PF15396.6 CDJ63993.1 - 1.5 8.8 9.5 1.9 8.4 9.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.16 CDJ63993.1 - 1.6 8.7 7.7 1.9 8.5 7.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HNOBA PF07701.14 CDJ63993.1 - 1.7 8.0 13.4 2.4 7.5 13.4 1.1 1 0 0 1 1 1 0 Heme NO binding associated ALMT PF11744.8 CDJ63993.1 - 1.8 7.3 8.9 2.2 7.0 8.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.6 CDJ63993.1 - 1.9 7.8 14.7 2.2 7.6 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Serinc PF03348.15 CDJ63993.1 - 2.2 7.1 5.2 2.3 7.1 5.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) AIF_C PF14721.6 CDJ63993.1 - 2.3 8.6 8.8 3.5 8.0 8.8 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2992 PF11208.8 CDJ63993.1 - 2.3 8.5 23.5 4.3 7.6 22.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2992) Pro_CA PF00484.19 CDJ63993.1 - 2.6 8.3 7.2 4.1 7.7 7.2 1.4 1 0 0 1 1 1 0 Carbonic anhydrase Zip PF02535.22 CDJ63993.1 - 3.7 6.7 4.3 4.2 6.5 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4411 PF14367.6 CDJ63993.1 - 3.8 7.4 16.9 4 7.3 16.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) Membralin PF09746.9 CDJ63993.1 - 4.1 6.3 9.9 5.2 6.0 9.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF3464 PF11947.8 CDJ63993.1 - 4.2 7.1 11.0 5.9 6.6 11.0 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CLN3 PF02487.17 CDJ63993.1 - 4.6 6.2 7.2 5.4 6.0 7.2 1.1 1 0 0 1 1 1 0 CLN3 protein Med15 PF09606.10 CDJ63993.1 - 5.2 5.6 30.2 6.3 5.3 30.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal OmpH PF03938.14 CDJ63993.1 - 6.3 7.1 35.1 9.2 6.6 35.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Hydin_ADK PF17213.3 CDJ63993.1 - 7.1 6.9 9.7 9.1 6.5 9.7 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Kei1 PF08552.11 CDJ63993.1 - 7.1 6.5 6.6 8.7 6.2 6.6 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Spt20 PF12090.8 CDJ63993.1 - 10 5.7 41.6 14 5.2 41.6 1.2 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ63994.1 - 5e-07 30.2 2.4 5e-07 30.2 2.4 4.6 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF2232 PF09991.9 CDJ63994.1 - 4.8 6.3 7.1 8.3 5.5 7.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Ribosomal_60s PF00428.19 CDJ63995.1 - 0.025 15.2 10.1 0.025 15.2 10.1 6.6 4 1 2 6 6 6 0 60s Acidic ribosomal protein Kinesin PF00225.23 CDJ63998.1 - 2.7e-19 69.3 2.6 1.4e-18 67.0 0.0 2.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ63998.1 - 5.7e-05 23.1 0.0 0.012 15.5 0.0 2.6 2 0 0 2 2 2 2 Microtubule binding Corona_I PF03187.14 CDJ63999.1 - 0.0066 16.1 1.0 0.42 10.2 0.1 2.2 1 1 1 2 2 2 2 Corona nucleocapsid I protein ANAPC_CDC26 PF10471.9 CDJ63999.1 - 0.0084 16.9 35.4 0.082 13.7 9.2 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex APC subunit CDC26 HSP20 PF00011.21 CDJ63999.1 - 0.043 14.0 0.0 0.043 14.0 0.0 3.2 4 0 0 4 4 4 0 Hsp20/alpha crystallin family CODH_A_N PF18537.1 CDJ63999.1 - 0.13 12.3 0.0 0.41 10.7 0.0 1.8 1 1 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain DUF4820 PF16091.5 CDJ63999.1 - 0.55 9.6 11.1 2 7.7 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF4328 PF14219.6 CDJ63999.1 - 0.72 9.4 5.7 2 8.0 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4328) PepSY_TM PF03929.16 CDJ63999.1 - 3.2 7.4 7.8 4.8 6.8 1.9 2.1 2 0 0 2 2 2 0 PepSY-associated TM region OPA3 PF07047.12 CDJ63999.1 - 4 7.2 10.7 3.8 7.3 1.3 3.2 3 0 0 3 3 3 0 Optic atrophy 3 protein (OPA3) NEMP PF10225.9 CDJ63999.1 - 8 6.1 6.6 12 5.5 2.5 2.1 2 0 0 2 2 2 0 NEMP family zf-CCHC PF00098.23 CDJ64004.1 - 6.4e-06 26.0 1.7 1.3e-05 25.0 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ64004.1 - 0.0025 17.6 0.6 0.0025 17.6 0.6 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ64004.1 - 0.019 14.7 0.2 0.045 13.5 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 CDJ64004.1 - 0.02 15.1 0.0 0.069 13.4 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 CDJ64004.1 - 0.031 14.3 0.2 0.063 13.2 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ64004.1 - 0.19 11.6 1.4 0.36 10.7 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_60s PF00428.19 CDJ64005.1 - 0.043 14.4 27.5 0.17 12.5 11.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4207 PF13904.6 CDJ64005.1 - 0.37 10.5 15.6 0.61 9.7 15.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) SR-25 PF10500.9 CDJ64005.1 - 0.44 10.1 26.1 14 5.2 26.1 2.1 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ64005.1 - 0.5 9.2 12.5 0.56 9.0 12.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ64005.1 - 0.53 9.0 12.5 0.68 8.6 12.5 1.3 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ64005.1 - 0.61 7.1 14.0 0.64 7.1 14.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 CDJ64005.1 - 0.69 9.1 20.1 0.78 8.9 20.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein LAP1C PF05609.12 CDJ64005.1 - 0.98 8.4 13.8 1.3 8.0 13.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) bZIP_C PF12498.8 CDJ64005.1 - 2.5 9.1 15.1 6.6 7.7 15.1 1.9 1 1 0 1 1 1 0 Basic leucine-zipper C terminal PPP4R2 PF09184.11 CDJ64005.1 - 3.3 7.2 9.8 4.2 6.9 9.8 1.1 1 0 0 1 1 1 0 PPP4R2 Roughex PF06020.11 CDJ64005.1 - 3.8 6.5 9.4 2 7.4 7.2 1.5 1 1 0 1 1 1 0 Drosophila roughex protein FAM199X PF15814.5 CDJ64005.1 - 5.8 5.9 19.9 2.3 7.2 17.7 1.3 1 1 0 1 1 1 0 Protein family FAM199X DUF4551 PF15087.6 CDJ64005.1 - 6.9 5.4 11.5 8.3 5.1 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF900 PF05990.12 CDJ64006.1 - 2.1e-17 63.4 0.0 1.3e-16 60.8 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) SUIM_assoc PF16619.5 CDJ64006.1 - 9.7e-06 25.6 13.9 0.023 14.7 7.1 2.8 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ64006.1 - 0.0047 15.9 8.5 0.059 12.3 0.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Herpes_IE1 PF07340.11 CDJ64006.1 - 0.051 12.5 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein DUF4834 PF16118.5 CDJ64006.1 - 0.074 14.0 5.5 2.8 8.9 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ64006.1 - 0.1 12.2 20.0 0.048 13.3 5.3 2.3 2 0 0 2 2 2 0 Spt20 family Hydrolase PF00702.26 CDJ64007.1 - 9.5e-10 39.1 7.4 0.00051 20.4 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ64007.1 - 0.024 14.4 0.0 0.059 13.1 0.0 1.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TFIIA PF03153.13 CDJ64007.1 - 0.11 12.5 47.0 0.19 11.7 11.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SpoIIIAH PF12685.7 CDJ64007.1 - 0.16 11.7 19.6 0.95 9.3 0.3 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein PNISR PF15996.5 CDJ64007.1 - 2 8.6 26.6 3 8.1 8.5 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DDHD PF02862.17 CDJ64007.1 - 2.6 8.2 10.7 3.9 7.6 0.4 2.3 2 0 0 2 2 2 0 DDHD domain DUF543 PF04418.12 CDJ64008.1 - 0.00058 19.8 0.1 0.00096 19.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF543) SR-25 PF10500.9 CDJ64008.1 - 5.4 6.6 11.5 14 5.2 0.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CKS PF01111.19 CDJ64011.1 - 1.1e-10 41.6 1.1 2e-10 40.8 1.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ribosomal_60s PF00428.19 CDJ64011.1 - 0.054 14.1 7.8 0.073 13.7 7.8 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ64012.1 - 0.014 15.0 73.5 0.035 13.7 31.1 2.1 2 0 0 2 2 2 0 Spt20 family RAP1 PF07218.11 CDJ64012.1 - 0.81 7.9 12.3 1 7.6 12.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PcfK PF14058.6 CDJ64012.1 - 1.9 8.8 26.5 2 8.7 6.1 2.2 2 0 0 2 2 2 0 PcfK-like protein RskA PF10099.9 CDJ64012.1 - 2 8.7 18.5 0.94 9.7 4.0 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA AF-4 PF05110.13 CDJ64012.1 - 7.1 4.6 48.4 10 4.0 48.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TFIIA PF03153.13 CDJ64014.1 - 0.005 16.9 2.4 0.005 16.9 2.4 8.7 5 2 2 7 7 7 1 Transcription factor IIA, alpha/beta subunit DUF4667 PF15700.5 CDJ64014.1 - 0.01 15.9 0.4 0.01 15.9 0.4 8.9 7 2 0 7 7 7 0 Domain of unknown function (DUF4667) HTH_23 PF13384.6 CDJ64014.1 - 0.034 14.0 0.0 0.36 10.7 0.0 2.9 1 0 0 1 1 1 0 Homeodomain-like domain Cullin PF00888.22 CDJ64014.1 - 0.034 12.8 0.1 0.055 12.1 0.1 1.2 1 0 0 1 1 1 0 Cullin family Asp-B-Hydro_N PF05279.11 CDJ64014.1 - 1.4 9.0 7.7 0.22 11.5 0.8 2.7 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region TFIIA PF03153.13 CDJ64015.1 - 0.021 14.8 21.4 0.026 14.5 21.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ64015.1 - 0.066 12.8 19.2 0.082 12.5 19.2 1.2 1 0 0 1 1 1 0 Spt20 family SARAF PF06682.12 CDJ64015.1 - 0.31 10.6 13.9 0.39 10.3 13.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4603 PF15376.6 CDJ64015.1 - 2.9 5.2 18.6 3.6 4.9 18.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) NPR3 PF03666.13 CDJ64015.1 - 3 6.6 15.2 4.1 6.1 15.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PEHE PF15275.6 CDJ64015.1 - 3.5 8.3 11.4 5.7 7.6 11.4 1.4 1 0 0 1 1 1 0 PEHE domain DUF3123 PF11321.8 CDJ64015.1 - 4.9 7.9 14.9 1 10.1 6.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) SR-25 PF10500.9 CDJ64015.1 - 9.1 5.8 24.9 0.11 12.2 9.6 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Fucose_iso_N2 PF07882.12 CDJ64018.1 - 0.36 10.4 0.9 0.68 9.5 0.9 1.4 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain SUIM_assoc PF16619.5 CDJ64018.1 - 1.4 9.1 12.1 4.5 7.4 12.1 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF755 PF05501.11 CDJ64019.1 - 0.0088 16.3 14.7 0.0088 16.3 14.7 6.6 7 1 1 8 8 8 1 Domain of unknown function (DUF755) LANC_like PF05147.13 CDJ64020.1 - 7e-29 100.5 1.9 2.2e-08 33.1 0.1 5.2 5 0 0 5 5 5 5 Lanthionine synthetase C-like protein EF-hand_6 PF13405.6 CDJ64021.1 - 0.04 13.8 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain Prophage_tail PF06605.11 CDJ64022.1 - 0.19 10.9 3.1 0.25 10.5 3.1 1.1 1 0 0 1 1 1 0 Prophage endopeptidase tail SHMT PF00464.19 CDJ64024.1 - 9.6e-154 511.8 0.0 1.7e-81 273.9 0.0 2.6 1 1 1 2 2 2 2 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CDJ64024.1 - 0.021 14.1 0.0 0.073 12.3 0.0 1.8 2 0 0 2 2 2 0 Beta-eliminating lyase PI3_PI4_kinase PF00454.27 CDJ64025.1 - 3e-33 115.7 0.0 5.3e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase BaxI_1 PF12811.7 CDJ64026.1 - 0.051 13.1 2.6 4 6.9 0.1 2.5 2 0 0 2 2 2 0 Bax inhibitor 1 like RGS-like PF09128.11 CDJ64026.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain RPN1_RPN2_N PF17781.1 CDJ64027.1 - 5e-112 374.3 0.5 7.9e-112 373.6 0.5 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CDJ64027.1 - 7.5e-27 93.1 0.1 1.7e-26 92.0 0.1 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CDJ64027.1 - 6.2e-11 42.2 34.7 0.00027 21.2 0.2 8.7 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CDJ64027.1 - 0.019 15.4 5.9 0.12 12.8 0.1 4.3 3 2 1 4 4 4 0 HEAT repeats PCI PF01399.27 CDJ64028.1 - 5.5e-12 46.1 0.2 1.3e-11 44.9 0.2 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 CDJ64028.1 - 0.033 14.3 0.1 0.68 10.2 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.22 CDJ64031.1 - 7.6 7.1 12.2 6.2 7.4 0.2 5.2 5 0 0 5 5 5 0 HEAT repeat zf-CCCH_2 PF14608.6 CDJ64032.1 - 6.7e-10 39.1 33.8 0.00019 21.8 5.9 3.3 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CDJ64032.1 - 2.9e-06 26.9 15.8 0.037 13.8 0.2 4.0 4 0 0 4 4 4 3 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ64032.1 - 0.003 17.4 0.8 0.003 17.4 0.8 4.0 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ64032.1 - 0.007 16.4 21.4 0.11 12.5 0.8 4.0 3 1 1 4 4 4 3 Zinc finger domain PWI PF01480.17 CDJ64032.1 - 0.013 15.8 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 PWI domain Nab2p_Zf1 PF18260.1 CDJ64032.1 - 0.017 15.0 13.4 0.02 14.8 2.4 2.6 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 zf-C3H1 PF10650.9 CDJ64032.1 - 0.081 12.7 2.2 0.27 11.0 2.2 1.9 1 0 0 1 1 1 0 Putative zinc-finger domain DEDD_Tnp_IS110 PF01548.17 CDJ64032.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Transposase ATG101 PF07855.12 CDJ64033.1 - 6e-08 32.8 0.0 0.031 14.3 0.0 3.2 3 0 0 3 3 3 3 Autophagy-related protein 101 Glycos_transf_1 PF00534.20 CDJ64034.1 - 7.1e-36 123.3 0.0 1.2e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ64034.1 - 9.7e-28 97.3 0.0 2.9e-27 95.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CDJ64034.1 - 1.6e-27 96.5 0.1 1.2e-26 93.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CDJ64034.1 - 1.8e-20 74.0 0.2 5.1e-19 69.3 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 CDJ64034.1 - 5.1e-15 55.8 0.2 1.6e-12 47.6 0.2 2.5 1 1 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase_C PF02806.18 CDJ64034.1 - 8.8e-15 55.0 0.0 2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Glyco_trans_1_2 PF13524.6 CDJ64034.1 - 0.0018 18.7 0.0 0.0049 17.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Collagen PF01391.18 CDJ64035.1 - 5e-05 23.0 35.6 0.00011 21.9 35.6 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) SpoIIE PF07228.12 CDJ64035.1 - 0.00063 19.7 0.0 0.0026 17.7 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Apt1 PF10351.9 CDJ64036.1 - 0.00044 19.2 7.5 0.00044 19.2 7.5 1.5 2 0 0 2 2 2 1 Golgi-body localisation protein domain SDA1 PF05285.12 CDJ64036.1 - 0.98 8.8 6.9 0.14 11.5 2.8 1.7 2 0 0 2 2 2 0 SDA1 Peptidase_S64 PF08192.11 CDJ64036.1 - 6.5 5.1 13.9 12 4.2 13.9 1.3 1 0 0 1 1 1 0 Peptidase family S64 Menin PF05053.13 CDJ64037.1 - 0.13 10.6 16.5 0.063 11.6 1.0 3.1 3 0 0 3 3 3 0 Menin SDA1 PF05285.12 CDJ64037.1 - 0.17 11.3 4.6 0.059 12.8 1.7 1.8 2 0 0 2 2 2 0 SDA1 Apt1 PF10351.9 CDJ64037.1 - 0.35 9.7 20.3 0.013 14.4 14.5 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Pacs-1 PF10254.9 CDJ64037.1 - 9.9 5.0 12.0 25 3.7 12.0 1.6 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein SR-25 PF10500.9 CDJ64038.1 - 0.0063 16.2 7.6 0.0063 16.2 7.6 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein RPN2_C PF18004.1 CDJ64038.1 - 0.35 10.8 7.9 0.41 10.5 0.0 3.0 2 1 1 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2457 PF10446.9 CDJ64038.1 - 2.1 7.4 10.0 0.61 9.2 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Lin-8 PF03353.15 CDJ64038.1 - 3.8 7.0 4.9 13 5.3 4.9 1.7 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mitofilin PF09731.9 CDJ64038.1 - 5.1 5.8 18.2 5.8 5.6 18.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Cyt_bd_oxida_II PF02322.15 CDJ64038.1 - 5.9 6.2 13.6 7.5 5.8 13.6 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Gti1_Pac2 PF09729.9 CDJ64038.1 - 6 6.9 6.0 13 5.9 0.4 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family GREB1 PF15782.5 CDJ64038.1 - 8.4 3.4 9.9 10 3.1 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF410 PF04190.13 CDJ64039.1 - 1.7e-13 51.0 0.0 1.7e-13 51.0 0.0 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF410) DUF5320 PF17253.2 CDJ64039.1 - 0.13 13.4 2.0 1.2 10.2 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Utp14 PF04615.13 CDJ64039.1 - 5.6 5.4 14.3 0.77 8.3 8.1 1.9 2 0 0 2 2 2 0 Utp14 protein SR-25 PF10500.9 CDJ64041.1 - 2.3 7.8 15.9 3.4 7.2 15.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein VAD1-2 PF15310.6 CDJ64041.1 - 6.2 6.6 7.3 3.8 7.3 1.0 2.1 2 0 0 2 2 2 0 Vitamin A-deficiency (VAD) rat model signalling CRAL_TRIO PF00650.20 CDJ64042.1 - 1.7e-11 44.1 0.0 2.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRT10 PF08728.10 CDJ64042.1 - 0.81 7.8 5.4 0.89 7.6 5.4 1.2 1 0 0 1 1 1 0 CRT10 Thioredoxin_8 PF13905.6 CDJ64043.1 - 7.7e-24 83.9 0.0 1.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CDJ64043.1 - 0.043 13.7 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family SCO1-SenC PF02630.14 CDJ64043.1 - 0.21 11.5 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC RTC PF01137.21 CDJ64044.1 - 3e-28 98.5 0.1 4e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CDJ64044.1 - 9.5e-12 45.3 7.8 1.3e-11 44.9 3.2 2.8 2 1 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain WD40 PF00400.32 CDJ64045.1 - 7.6e-30 102.5 25.3 2.8e-05 24.8 0.1 12.1 11 1 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ64045.1 - 2.3e-12 47.0 0.4 2.4 8.5 0.0 8.3 6 2 4 10 10 10 3 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CDJ64045.1 - 1.6e-08 34.8 1.1 3.9e-08 33.6 1.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 CDJ64045.1 - 0.00074 18.3 0.0 1.8 7.1 0.0 4.1 4 0 0 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CDJ64045.1 - 0.13 11.6 0.0 0.85 8.9 0.0 2.3 4 0 0 4 4 4 0 WD40-like domain SR-25 PF10500.9 CDJ64045.1 - 0.15 11.7 14.5 0.56 9.8 5.0 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.10 CDJ64045.1 - 2.8 8.0 6.8 1.2 9.1 2.2 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MFS_1 PF07690.16 CDJ64046.1 - 1.7e-30 106.2 25.2 3.8e-22 78.7 2.4 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily BT1 PF03092.16 CDJ64046.1 - 0.39 8.9 18.0 0.27 9.4 4.0 3.2 4 0 0 4 4 4 0 BT1 family CPSase_L_D2 PF02786.17 CDJ64048.1 - 2.9e-108 360.2 0.0 4.1e-77 258.4 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CDJ64048.1 - 2.2e-43 147.2 0.0 4.9e-43 146.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CDJ64048.1 - 3.3e-41 141.2 0.0 8.5e-41 139.8 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 CDJ64048.1 - 6.1e-38 129.9 1.7 8.7e-38 129.4 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CDJ64048.1 - 1.6e-16 60.4 0.0 2.2e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CDJ64048.1 - 1.1e-15 57.8 0.0 3e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CDJ64048.1 - 5.5e-13 48.8 0.0 1.4e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 CDJ64048.1 - 7.9e-11 42.0 0.0 7.8e-10 38.8 0.0 2.8 2 1 0 2 2 2 1 MGS-like domain Peptidase_C26 PF07722.13 CDJ64048.1 - 6.1e-05 22.9 1.8 0.001 18.9 0.1 2.7 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 CDJ64048.1 - 0.00026 21.1 0.1 0.27 11.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 CDJ64048.1 - 0.0011 18.5 0.1 0.0031 17.0 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain DJ-1_PfpI PF01965.24 CDJ64048.1 - 0.037 13.8 0.1 0.29 10.9 0.0 2.4 3 0 0 3 3 3 0 DJ-1/PfpI family Nitro_FeMo-Co PF02579.17 CDJ64048.1 - 0.33 11.3 1.8 6.8 7.1 0.0 3.4 4 0 0 4 4 3 0 Dinitrogenase iron-molybdenum cofactor WD40 PF00400.32 CDJ64049.1 - 0.028 15.3 0.4 0.028 15.3 0.4 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Glyco_tran_28_C PF04101.16 CDJ64050.1 - 6e-16 58.9 0.0 8.9e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain RNA_polI_A34 PF08208.11 CDJ64051.1 - 0.13 12.3 27.2 0.19 11.8 27.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4746 PF15928.5 CDJ64051.1 - 3.5 7.0 15.5 4.9 6.5 15.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) Smg8_Smg9 PF10220.9 CDJ64051.1 - 5 5.3 14.1 6.1 5.0 14.1 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Spore_coat_CotO PF14153.6 CDJ64051.1 - 9.8 6.1 20.9 15 5.4 20.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO SNF2_N PF00176.23 CDJ64052.1 - 4.1e-16 58.6 0.0 1.1e-12 47.4 0.0 3.0 3 0 0 3 3 3 2 SNF2 family N-terminal domain zf-C4_Topoisom PF01396.19 CDJ64052.1 - 5e-07 29.4 4.5 1.6e-06 27.8 4.5 1.9 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Helicase_C PF00271.31 CDJ64052.1 - 0.00061 20.1 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HNH PF01844.23 CDJ64052.1 - 0.00085 19.5 0.0 0.003 17.7 0.0 2.0 1 0 0 1 1 1 1 HNH endonuclease ResIII PF04851.15 CDJ64052.1 - 0.0038 17.2 0.0 0.014 15.4 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ64052.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase FixG_C PF11614.8 CDJ64054.1 - 0.0085 16.3 0.2 0.014 15.6 0.2 1.3 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Cyclin PF08613.11 CDJ64055.1 - 8.4e-31 107.5 0.2 8.4e-31 107.5 0.2 3.1 4 1 0 4 4 4 1 Cyclin Cyclin_N PF00134.23 CDJ64055.1 - 1e-06 28.5 0.1 1e-06 28.5 0.1 3.4 3 1 0 3 3 3 1 Cyclin, N-terminal domain GHMP_kinases_N PF00288.26 CDJ64055.1 - 0.00016 21.8 0.2 0.00046 20.4 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain TauE PF01925.19 CDJ64056.1 - 3.2e-17 63.0 21.8 3.7e-14 52.9 6.9 3.3 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE DUF2722 PF10846.8 CDJ64056.1 - 0.028 13.4 15.4 0.29 10.0 0.4 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) DAG_kinase_N PF14513.6 CDJ64056.1 - 0.31 11.2 3.0 1.6 8.9 0.1 2.7 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus Med15 PF09606.10 CDJ64056.1 - 4.3 5.9 34.4 0.09 11.5 13.2 3.1 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAN_4 PF14295.6 CDJ64057.1 - 8e-48 160.1 76.6 1.4e-06 28.1 0.3 11.8 11 0 0 11 11 11 11 PAN domain PAN_1 PF00024.26 CDJ64057.1 - 2e-45 152.6 54.6 5.7e-07 29.4 0.5 11.7 9 3 3 12 12 12 10 PAN domain PAN_3 PF08277.12 CDJ64057.1 - 0.015 15.1 0.9 0.015 15.1 0.9 9.2 10 0 0 10 10 10 0 PAN-like domain MASE1 PF05231.14 CDJ64057.1 - 6.5 5.8 15.8 0.18 10.9 9.1 1.7 2 0 0 2 2 2 0 MASE1 TSP_1 PF00090.19 CDJ64058.1 - 6.5e-06 26.3 3.4 6.5e-06 26.3 3.4 4.5 5 1 0 5 5 5 1 Thrombospondin type 1 domain RskA PF10099.9 CDJ64058.1 - 0.0072 16.6 19.1 0.0072 16.6 19.1 7.2 5 2 1 6 6 6 2 Anti-sigma-K factor rskA DUF4131 PF13567.6 CDJ64058.1 - 0.082 12.6 7.9 1.1 8.8 1.6 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_S64 PF08192.11 CDJ64059.1 - 1.7 7.1 22.6 2.2 6.7 22.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 PCI PF01399.27 CDJ64060.1 - 4e-07 30.5 0.0 8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 PCI domain DA1-like PF12315.8 CDJ64060.1 - 0.016 14.6 0.7 0.041 13.2 0.7 1.7 1 1 0 1 1 1 0 Protein DA1 IMUP PF15761.5 CDJ64060.1 - 0.041 14.6 5.1 0.099 13.3 5.1 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein FeoC PF09012.10 CDJ64060.1 - 0.07 13.2 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator X8 PF07983.13 CDJ64060.1 - 0.14 12.9 0.0 0.26 12.0 0.0 1.4 1 0 0 1 1 1 0 X8 domain DUF4509 PF14970.6 CDJ64060.1 - 0.76 9.7 8.1 0.85 9.5 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4509) SR-25 PF10500.9 CDJ64060.1 - 2.5 7.6 13.8 0.38 10.3 9.4 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_S10 PF00338.22 CDJ64061.1 - 7.4e-09 35.7 0.3 7.4e-09 35.7 0.3 4.4 4 1 0 4 4 4 1 Ribosomal protein S10p/S20e SR-25 PF10500.9 CDJ64061.1 - 0.0002 21.1 14.2 0.0002 21.1 14.2 10.0 6 2 4 10 10 10 4 Nuclear RNA-splicing-associated protein TPR_1 PF00515.28 CDJ64061.1 - 0.0012 18.6 5.9 1.3 8.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ64061.1 - 0.0088 16.1 14.0 0.28 11.4 0.0 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat RNA_pol_Rpc4 PF05132.14 CDJ64062.1 - 1.1e-17 64.9 0.0 1.1e-17 64.9 0.0 6.7 2 2 3 5 5 5 1 RNA polymerase III RPC4 SR-25 PF10500.9 CDJ64062.1 - 0.013 15.1 14.5 0.013 15.1 14.5 4.9 3 1 1 4 4 4 0 Nuclear RNA-splicing-associated protein BPL_LplA_LipB PF03099.19 CDJ64063.1 - 4.5e-08 33.1 0.4 3.1e-06 27.1 0.1 2.8 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family RskA PF10099.9 CDJ64063.1 - 3.9e-05 24.0 8.2 3.9e-05 24.0 8.2 8.9 2 2 5 7 7 7 1 Anti-sigma-K factor rskA PIP5K PF01504.18 CDJ64063.1 - 0.53 9.5 32.7 1.4 8.1 0.3 4.2 3 1 0 3 3 3 0 Phosphatidylinositol-4-phosphate 5-Kinase PucR PF07905.11 CDJ64063.1 - 0.86 9.9 0.0 0.86 9.9 0.0 2.4 3 0 0 3 3 3 0 Purine catabolism regulatory protein-like family Diphthamide_syn PF01866.17 CDJ64064.1 - 1.1e-57 195.8 0.0 8.6e-57 192.9 0.0 2.0 1 1 0 1 1 1 1 Putative diphthamide synthesis protein RskA PF10099.9 CDJ64064.1 - 0.021 15.1 13.8 0.12 12.6 9.9 2.7 3 0 0 3 3 3 0 Anti-sigma-K factor rskA SOG2 PF10428.9 CDJ64064.1 - 6.5 5.8 48.2 0.43 9.7 37.1 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein SPX PF03105.19 CDJ64065.1 - 0.075 12.9 0.1 0.075 12.9 0.1 3.8 3 1 0 3 3 3 0 SPX domain PhoLip_ATPase_N PF16209.5 CDJ64066.1 - 7.1e-24 83.3 1.5 1.4e-23 82.4 1.5 1.4 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal TFIIA PF03153.13 CDJ64066.1 - 0.00034 20.7 6.4 0.00035 20.7 6.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ64066.1 - 0.012 15.6 2.6 0.014 15.4 2.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FHIPEP PF00771.20 CDJ64066.1 - 0.014 13.9 0.3 0.018 13.5 0.3 1.1 1 0 0 1 1 1 0 FHIPEP family SprA-related PF12118.8 CDJ64066.1 - 0.018 14.2 7.1 0.028 13.6 7.1 1.3 1 0 0 1 1 1 0 SprA-related family Spt20 PF12090.8 CDJ64066.1 - 0.022 14.4 14.5 0.04 13.5 14.5 1.4 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.10 CDJ64066.1 - 0.035 12.8 9.9 0.044 12.5 9.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HCO3_cotransp PF00955.21 CDJ64066.1 - 0.11 11.3 0.1 0.14 11.0 0.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family E1-E2_ATPase PF00122.20 CDJ64066.1 - 0.15 11.6 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 E1-E2 ATPase Utp21 PF04192.12 CDJ64068.1 - 0.4 10.1 9.0 0.74 9.3 9.0 1.3 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Tic110 PF16940.5 CDJ64068.1 - 0.87 8.0 6.2 1.3 7.4 6.2 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter PAT1 PF09770.9 CDJ64068.1 - 4.1 5.6 21.3 5.8 5.1 21.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DNA_gyraseB PF00204.25 CDJ64069.1 - 6.9e-25 87.5 0.7 1.5e-15 57.1 0.5 4.3 3 0 0 3 3 3 2 DNA gyrase B DNA_gyraseB_C PF00986.21 CDJ64069.1 - 1.1e-15 57.5 0.1 2.6e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus Toprim PF01751.22 CDJ64069.1 - 5.4e-14 52.3 0.3 2.2e-06 27.8 0.2 3.1 2 0 0 2 2 2 2 Toprim domain SR-25 PF10500.9 CDJ64069.1 - 3.8e-05 23.4 6.7 3.8e-05 23.4 6.7 5.9 4 2 2 6 6 6 1 Nuclear RNA-splicing-associated protein Tetraspanin PF00335.20 CDJ64069.1 - 0.27 10.9 3.5 3.3 7.3 2.1 2.6 2 1 0 2 2 2 0 Tetraspanin family Rad51 PF08423.11 CDJ64070.1 - 8.2e-102 339.8 0.0 9.2e-102 339.7 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CDJ64070.1 - 0.0002 21.0 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CDJ64070.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Tfb5 PF06331.12 CDJ64071.1 - 1.4e-20 73.0 0.2 1.8e-20 72.7 0.2 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Sec23_trunk PF04811.15 CDJ64072.1 - 9.3e-37 126.9 0.0 5.5e-24 85.1 0.0 3.2 2 1 1 3 3 3 3 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CDJ64072.1 - 1.1e-30 106.2 0.0 3.5e-30 104.6 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CDJ64072.1 - 1.8e-05 24.5 0.5 5e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain FAM199X PF15814.5 CDJ64072.1 - 1.1 8.3 5.2 2.2 7.3 5.2 1.5 1 0 0 1 1 1 0 Protein family FAM199X FIST PF08495.10 CDJ64072.1 - 6.6 6.7 7.9 15 5.6 7.9 1.6 1 0 0 1 1 1 0 FIST N domain Actin PF00022.19 CDJ64073.1 - 3.8e-25 88.3 0.0 3.8e-22 78.5 0.0 2.9 2 1 0 2 2 2 2 Actin INO80_Ies4 PF08193.11 CDJ64073.1 - 0.21 11.5 2.8 0.33 10.9 2.8 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 DUF4168 PF13767.6 CDJ64075.1 - 0.11 13.7 0.0 0.28 12.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) Rad21_Rec8 PF04824.16 CDJ64076.1 - 8e-06 25.1 0.0 2.8e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SPRY PF00622.28 CDJ64077.1 - 4.7e-05 23.5 0.3 0.0052 16.9 0.0 3.3 3 0 0 3 3 3 2 SPRY domain zf-RING_2 PF13639.6 CDJ64078.1 - 4.3e-08 33.4 3.0 4.3e-08 33.4 3.0 2.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ64078.1 - 2.9e-07 30.2 2.5 2.9e-07 30.2 2.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ64078.1 - 3.1e-07 30.3 7.6 3.2e-07 30.2 1.3 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDJ64078.1 - 8.8e-06 25.5 2.7 8.8e-06 25.5 2.7 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ64078.1 - 1e-05 25.7 1.4 1e-05 25.7 1.4 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ64078.1 - 1.7e-05 24.6 1.1 1.7e-05 24.6 1.1 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ64078.1 - 0.00019 21.4 2.1 0.00019 21.4 2.1 3.1 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CDJ64078.1 - 0.00037 20.3 1.5 0.00037 20.3 1.5 3.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CDJ64078.1 - 0.064 13.4 7.9 0.098 12.8 4.5 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CDJ64078.1 - 0.12 12.2 9.5 0.08 12.8 1.1 3.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 CDJ64078.1 - 1.1 9.1 3.8 0.68 9.8 1.1 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 CDJ64078.1 - 1.5 8.9 4.4 0.37 10.9 0.5 2.0 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 CDJ64078.1 - 3.2 7.5 7.5 0.34 10.6 2.1 2.0 2 0 0 2 2 2 0 P-11 zinc finger DUF4820 PF16091.5 CDJ64078.1 - 3.9 6.8 7.9 13 5.1 7.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM176 PF14851.6 CDJ64078.1 - 6.1 6.5 6.2 25 4.5 6.2 2.1 1 0 0 1 1 1 0 FAM176 family zf-RING_10 PF16685.5 CDJ64078.1 - 8.5 6.6 7.0 0.96 9.6 1.6 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 HEAT PF02985.22 CDJ64079.1 - 2.1 8.8 9.3 22 5.6 0.2 4.7 4 0 0 4 4 4 0 HEAT repeat Ribosomal_S15 PF00312.22 CDJ64080.1 - 1.5e-22 79.6 1.4 2.4e-22 78.9 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Ank_2 PF12796.7 CDJ64081.1 - 1.1e-31 109.3 4.8 2.9e-09 37.4 0.4 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ64081.1 - 5.8e-24 84.2 2.9 1.5e-09 38.2 0.0 5.9 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ64081.1 - 8.1e-24 81.1 2.5 0.0061 17.0 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 CDJ64081.1 - 2e-22 79.0 5.0 5.3e-06 26.6 0.0 5.7 4 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 CDJ64081.1 - 1.2e-20 73.0 16.0 0.0021 18.4 0.1 7.5 9 0 0 9 9 9 5 Ankyrin repeat TPR_17 PF13431.6 CDJ64081.1 - 0.029 14.7 0.0 13 6.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ64081.1 - 0.083 12.6 0.0 18 5.1 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 CDJ64081.1 - 2.3 9.3 6.5 9.7 7.3 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat UQ_con PF00179.26 CDJ64082.1 - 2.7e-51 172.9 0.0 3.4e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ64082.1 - 0.0002 21.1 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ64082.1 - 0.053 13.8 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Ring_hydroxyl_B PF00866.18 CDJ64082.1 - 0.099 12.7 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Ring hydroxylating beta subunit APG6 PF04111.12 CDJ64084.1 - 3.9e-46 157.3 0.0 6.1e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CDJ64084.1 - 7.5e-12 45.9 7.3 1.2e-11 45.3 7.3 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Lectin_N PF03954.14 CDJ64084.1 - 0.017 14.8 1.2 0.032 14.0 1.2 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4164 PF13747.6 CDJ64084.1 - 0.052 13.8 7.8 0.14 12.5 7.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF4407 PF14362.6 CDJ64084.1 - 0.057 12.8 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Swi5 PF07061.11 CDJ64084.1 - 0.47 10.6 3.3 0.95 9.6 3.3 1.5 1 0 0 1 1 1 0 Swi5 DivIC PF04977.15 CDJ64084.1 - 1.1 9.0 4.4 2.4 8.0 4.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Abi_C PF14355.6 CDJ64085.1 - 0.015 15.4 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 Abortive infection C-terminus OTU PF02338.19 CDJ64088.1 - 7.1e-15 55.6 0.0 1.9e-14 54.2 0.0 1.7 1 1 0 1 1 1 1 OTU-like cysteine protease Sec1 PF00995.23 CDJ64090.1 - 0.0044 16.3 0.0 0.0076 15.5 0.0 1.4 2 0 0 2 2 2 1 Sec1 family Mito_carr PF00153.27 CDJ64091.1 - 3.9e-26 90.8 3.7 1e-07 31.7 0.1 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein TEX13 PF15186.6 CDJ64091.1 - 0.034 13.9 0.9 0.079 12.6 0.9 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Lzipper-MIP1 PF14389.6 CDJ64091.1 - 0.035 14.4 3.9 0.039 14.2 0.5 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Metallothio PF00131.20 CDJ64091.1 - 0.23 11.6 5.1 0.55 10.4 5.1 1.6 1 0 0 1 1 1 0 Metallothionein DUF4692 PF15763.5 CDJ64091.1 - 0.65 10.5 6.7 0.063 13.8 1.6 1.9 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DUF1682 PF07946.14 CDJ64092.1 - 2.7e-58 197.7 0.8 3.5e-58 197.3 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) CRA PF06589.11 CDJ64092.1 - 5.3 7.2 10.1 3.5 7.7 7.2 1.9 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Chorismate_bind PF00425.18 CDJ64094.1 - 1.4e-22 80.5 0.0 8.5e-15 55.0 0.0 2.3 2 0 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 CDJ64094.1 - 2.2e-06 27.9 1.0 0.0003 21.0 0.1 3.1 3 1 0 3 3 3 1 Anthranilate synthase component I, N terminal region GATase PF00117.28 CDJ64094.1 - 3.3e-06 27.0 0.1 5.2e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase PF00117.28 CDJ64095.1 - 3.5e-15 56.3 0.0 3.9e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_M14 PF00246.24 CDJ64096.1 - 0.038 13.8 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 Zinc carboxypeptidase Spt20 PF12090.8 CDJ64097.1 - 0.00011 22.0 48.6 0.051 13.2 5.8 3.2 3 0 0 3 3 3 3 Spt20 family ANAPC_CDC26 PF10471.9 CDJ64097.1 - 0.00037 21.3 48.5 0.03 15.1 6.8 4.5 4 0 0 4 4 4 3 Anaphase-promoting complex APC subunit CDC26 EPL1 PF10513.9 CDJ64097.1 - 0.0026 18.1 7.0 2.7 8.4 0.5 3.3 3 0 0 3 3 3 2 Enhancer of polycomb-like DUF2722 PF10846.8 CDJ64097.1 - 0.01 14.8 36.3 0.52 9.2 2.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) DUF2828 PF11443.8 CDJ64097.1 - 0.6 8.1 5.7 0.1 10.6 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF3371 PF11851.8 CDJ64097.1 - 2.7 9.1 24.0 33 5.6 0.3 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3371) Roughex PF06020.11 CDJ64097.1 - 4.1 6.4 30.5 0.061 12.4 1.2 3.3 3 0 0 3 3 3 0 Drosophila roughex protein Presenilin PF01080.17 CDJ64097.1 - 7.1 5.3 14.5 6.8 5.3 9.3 2.4 2 1 0 2 2 2 0 Presenilin GvpL_GvpF PF06386.11 CDJ64098.1 - 5 7.0 13.4 1.3 8.9 0.6 2.6 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF RAP1 PF07218.11 CDJ64098.1 - 9.4 4.4 7.4 14 3.8 7.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Acyltransferase PF01553.21 CDJ64099.1 - 0.00022 20.9 0.2 0.00045 19.9 0.1 1.6 1 1 0 1 1 1 1 Acyltransferase BCNT PF07572.12 CDJ64101.1 - 3.6e-09 36.6 0.6 6.1e-09 35.8 0.1 1.6 2 0 0 2 2 2 1 Bucentaur or craniofacial development Yippee-Mis18 PF03226.14 CDJ64102.1 - 1.2e-13 51.2 0.2 1.5e-13 50.8 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-P11 PF03854.14 CDJ64102.1 - 0.0059 16.3 0.9 0.013 15.2 0.9 1.5 1 0 0 1 1 1 1 P-11 zinc finger zinc_ribbon_6 PF14599.6 CDJ64102.1 - 0.012 15.6 0.2 0.012 15.6 0.2 2.2 2 0 0 2 2 2 0 Zinc-ribbon RIG-I_C-RD PF11648.8 CDJ64102.1 - 0.034 14.4 0.3 0.051 13.8 0.3 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I zf-CHY PF05495.12 CDJ64102.1 - 0.04 14.4 7.6 0.2 12.1 7.6 1.9 1 1 0 1 1 1 0 CHY zinc finger HNH_5 PF14279.6 CDJ64102.1 - 0.043 13.7 0.7 6.1 6.8 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease DUF2321 PF10083.9 CDJ64102.1 - 0.066 12.8 0.6 0.096 12.3 0.6 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Ribosomal_L40e PF01020.17 CDJ64102.1 - 0.16 11.9 3.5 0.45 10.4 2.0 2.4 2 1 1 3 3 3 0 Ribosomal L40e family Zn_ribbon_SprT PF17283.2 CDJ64102.1 - 0.26 11.3 5.3 0.19 11.6 1.5 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DZR PF12773.7 CDJ64102.1 - 0.62 10.1 4.2 7.4 6.7 0.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon CAF1 PF04857.20 CDJ64104.1 - 0.0088 15.3 3.8 0.0089 15.2 3.8 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease CPSF100_C PF13299.6 CDJ64104.1 - 0.36 11.0 9.4 0.79 9.9 9.4 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ALMT PF11744.8 CDJ64104.1 - 0.52 9.1 12.1 0.64 8.8 12.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Phage_holin_3_5 PF16085.5 CDJ64104.1 - 1.4 9.1 5.9 2.6 8.2 5.9 1.5 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III CLN3 PF02487.17 CDJ64104.1 - 1.4 7.9 9.6 1.8 7.5 9.6 1.2 1 0 0 1 1 1 0 CLN3 protein MAT1 PF06391.13 CDJ64104.1 - 1.7 8.5 24.1 2.5 7.9 24.1 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 UPF0061 PF02696.14 CDJ64104.1 - 2.1 7.0 15.6 3 6.5 15.6 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family P16-Arc PF04699.14 CDJ64104.1 - 2.4 8.6 13.8 4.8 7.7 13.8 1.4 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) PAT1 PF09770.9 CDJ64104.1 - 3.2 5.9 28.9 4.3 5.5 28.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TYW3 PF02676.14 CDJ64104.1 - 3.6 6.9 7.9 6.7 6.0 7.9 1.4 1 0 0 1 1 1 0 Methyltransferase TYW3 RR_TM4-6 PF06459.12 CDJ64104.1 - 4.7 6.9 14.0 7.8 6.2 14.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vac7 PF12751.7 CDJ64104.1 - 6 6.2 7.4 8.6 5.7 7.4 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 PDDEXK_6 PF04720.12 CDJ64104.1 - 6.2 6.7 12.3 9.8 6.1 12.3 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Presenilin PF01080.17 CDJ64104.1 - 6.5 5.4 18.4 9.8 4.8 18.4 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ64104.1 - 7.1 6.6 10.8 10 6.1 10.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4569 PF15133.6 CDJ64104.1 - 7.2 6.2 21.3 9.8 5.8 21.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) FAM60A PF15396.6 CDJ64104.1 - 7.6 6.5 11.5 12 5.8 11.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF2828 PF11443.8 CDJ64104.1 - 7.8 4.4 13.7 10 4.0 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SLC12 PF03522.15 CDJ64104.1 - 9.8 5.1 17.5 13 4.7 17.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 UPF0154 PF03672.13 CDJ64105.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Ricin_B_lectin PF00652.22 CDJ64106.1 - 4e-16 59.4 0.1 1.7e-11 44.5 0.1 3.5 3 1 1 4 4 2 2 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDJ64106.1 - 4.4e-09 35.9 0.1 8.9e-09 34.9 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 CDJ64106.1 - 1.5e-06 28.1 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CDJ64106.1 - 0.00049 20.0 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Spt20 PF12090.8 CDJ64106.1 - 0.001 18.7 13.0 0.0017 18.0 13.0 1.3 1 0 0 1 1 1 1 Spt20 family Glyco_tranf_2_2 PF10111.9 CDJ64106.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF2722 PF10846.8 CDJ64106.1 - 0.056 12.4 12.9 0.081 11.9 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) HgmA PF04209.13 CDJ64106.1 - 0.057 12.1 0.2 0.12 11.0 0.3 1.4 2 0 0 2 2 2 0 homogentisate 1,2-dioxygenase LANC_like PF05147.13 CDJ64106.1 - 0.15 10.6 0.5 0.33 9.5 0.0 1.7 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein TFIIA PF03153.13 CDJ64106.1 - 0.2 11.6 14.4 0.28 11.2 14.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ64106.1 - 0.48 11.4 3.6 0.87 10.6 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ64106.1 - 0.51 10.3 5.4 0.76 9.7 5.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Glyco_transf_21 PF13506.6 CDJ64106.1 - 0.57 9.6 0.0 0.57 9.6 0.0 2.3 2 1 0 2 2 1 0 Glycosyl transferase family 21 Sarcoglycan_2 PF05510.13 CDJ64106.1 - 0.83 8.4 3.6 1.2 7.8 3.6 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon EIF4E-T PF10477.9 CDJ64107.1 - 5.1e-05 22.3 18.7 5.3e-05 22.3 18.7 1.1 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Presenilin PF01080.17 CDJ64107.1 - 9.4e-05 21.3 11.8 0.00011 21.1 11.8 1.3 1 0 0 1 1 1 1 Presenilin Shadoo PF14999.6 CDJ64107.1 - 0.0049 17.0 0.0 0.0049 17.0 0.0 3.4 2 1 0 2 2 1 1 Shadow of prion protein, neuroprotective FAM60A PF15396.6 CDJ64107.1 - 0.019 15.0 11.2 0.03 14.3 11.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF5523 PF17661.1 CDJ64107.1 - 0.037 13.7 18.0 0.051 13.3 18.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) AF-4 PF05110.13 CDJ64107.1 - 0.15 10.1 24.8 0.19 9.8 24.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Med19 PF10278.9 CDJ64107.1 - 0.53 10.2 15.9 0.69 9.8 9.0 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 NPR1_interact PF15699.5 CDJ64107.1 - 1.3 9.7 20.9 7.5 7.2 0.5 2.4 1 1 1 2 2 2 0 NPR1 interacting PAT1 PF09770.9 CDJ64107.1 - 1.8 6.7 29.5 2.6 6.2 29.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ64107.1 - 1.8 5.6 18.9 1.9 5.5 18.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 CDJ64107.1 - 1.9 7.4 16.5 2.8 6.9 16.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF4551 PF15087.6 CDJ64107.1 - 2 7.2 17.2 2.4 6.9 17.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Peptidase_U57 PF05582.12 CDJ64107.1 - 2 7.6 10.4 2.2 7.5 3.6 2.1 2 0 0 2 2 2 0 YabG peptidase U57 SAPS PF04499.15 CDJ64107.1 - 3.3 6.4 13.3 4.4 6.0 13.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDK5_activator PF03261.15 CDJ64107.1 - 3.7 7.0 14.0 4.8 6.6 14.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CD20 PF04103.15 CDJ64107.1 - 6.7 6.8 7.9 3.4 7.7 0.9 2.5 1 1 1 2 2 2 0 CD20-like family DAGK_cat PF00781.24 CDJ64107.1 - 7.3 6.2 6.6 7.1 6.3 1.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Lin-8 PF03353.15 CDJ64108.1 - 5.6e-06 26.1 31.0 8.2e-06 25.6 31.0 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ64108.1 - 0.032 14.2 28.4 0.051 13.5 28.4 1.3 1 0 0 1 1 1 0 SPX domain CRT10 PF08728.10 CDJ64108.1 - 0.8 7.8 15.3 0.7 8.0 15.3 1.0 1 0 0 1 1 1 0 CRT10 Dapper PF15268.6 CDJ64108.1 - 1.3 7.7 47.2 1.6 7.5 47.2 1.0 1 0 0 1 1 1 0 Dapper DUF4192 PF13830.6 CDJ64108.1 - 2.3 8.2 19.0 3.8 7.5 19.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CAC1F_C PF16885.5 CDJ64108.1 - 5.5 6.6 28.7 7.2 6.2 28.7 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term PAT1 PF09770.9 CDJ64108.1 - 7.8 4.6 65.5 8.8 4.5 65.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SUIM_assoc PF16619.5 CDJ64109.1 - 0.0099 15.9 1.7 0.013 15.5 1.7 1.2 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ64110.1 - 0.13 11.8 14.7 0.35 10.5 14.7 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Corona_nucleoca PF00937.18 CDJ64110.1 - 0.21 10.6 6.6 0.54 9.2 6.6 1.6 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1645 PF07816.11 CDJ64110.1 - 0.8 10.3 10.0 0.25 11.9 6.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) CEP19 PF14933.6 CDJ64110.1 - 2.4 8.4 4.4 5 7.4 0.7 2.5 2 0 0 2 2 2 0 CEP19-like protein AF-4 PF05110.13 CDJ64110.1 - 2.9 5.9 22.6 0.37 8.8 18.7 1.4 1 1 0 1 1 1 0 AF-4 proto-oncoprotein DUF4429 PF14472.6 CDJ64110.1 - 4.8 7.8 6.0 19 5.9 0.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4429) PAP1 PF08601.10 CDJ64110.1 - 6.4 6.4 13.1 3.5 7.3 8.0 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 TFIIA PF03153.13 CDJ64111.1 - 0.00012 22.2 32.9 0.0011 19.1 17.2 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF1631 PF07793.11 CDJ64111.1 - 0.00032 19.3 15.3 0.00032 19.3 15.3 2.7 2 1 0 2 2 1 1 Protein of unknown function (DUF1631) DDHD PF02862.17 CDJ64111.1 - 0.024 14.8 2.5 0.23 11.6 0.3 2.1 2 0 0 2 2 2 0 DDHD domain Senescence_reg PF04520.13 CDJ64111.1 - 0.036 14.9 12.8 1 10.2 2.2 2.3 2 0 0 2 2 2 0 Senescence regulator Presenilin PF01080.17 CDJ64111.1 - 0.084 11.6 7.6 0.12 11.2 3.1 2.0 2 0 0 2 2 2 0 Presenilin PIP5K PF01504.18 CDJ64111.1 - 0.21 10.8 0.5 0.94 8.6 0.2 1.8 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Suf PF05843.14 CDJ64111.1 - 0.27 11.2 16.8 0.2 11.6 8.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4050 PF13259.6 CDJ64111.1 - 0.34 11.2 8.6 5 7.4 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) DUF1980 PF09323.10 CDJ64111.1 - 0.36 10.7 1.7 0.95 9.3 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) SpoIIP PF07454.11 CDJ64111.1 - 0.42 10.0 5.7 0.36 10.2 1.1 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RIC3 PF15361.6 CDJ64111.1 - 0.65 10.4 7.9 0.26 11.7 3.2 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Gastrin PF00918.17 CDJ64111.1 - 1.1 10.2 10.8 0.4 11.7 5.1 2.4 2 0 0 2 2 2 0 Gastrin/cholecystokinin family EPL1 PF10513.9 CDJ64111.1 - 1.2 9.6 7.5 17 5.7 4.5 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like YppG PF14179.6 CDJ64111.1 - 1.3 9.7 27.3 2.7 8.7 1.4 2.4 2 0 0 2 2 2 0 YppG-like protein Lin-8 PF03353.15 CDJ64111.1 - 2 7.9 11.8 0.35 10.4 3.5 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CPSF100_C PF13299.6 CDJ64111.1 - 2.1 8.5 10.6 4.4 7.5 5.0 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Hydin_ADK PF17213.3 CDJ64111.1 - 2.6 8.3 13.8 5.3 7.3 7.6 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain RR_TM4-6 PF06459.12 CDJ64111.1 - 3.4 7.4 11.7 3.2 7.5 6.6 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ64111.1 - 3.9 7.4 4.7 3.9 7.4 1.8 2.0 2 0 0 2 2 2 0 Protein Family FAM60A Velvet PF11754.8 CDJ64111.1 - 4.1 7.3 10.6 3.7 7.4 5.5 2.1 2 0 0 2 2 2 0 Velvet factor Pex14_N PF04695.13 CDJ64111.1 - 4.2 8.0 38.2 1.1 9.9 18.8 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gti1_Pac2 PF09729.9 CDJ64111.1 - 4.7 7.3 6.7 9 6.3 3.3 2.0 2 0 0 2 2 2 0 Gti1/Pac2 family Ndc1_Nup PF09531.10 CDJ64111.1 - 5.5 5.6 13.6 3.1 6.4 5.2 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 CDJ64111.1 - 6.1 3.8 8.8 2.8 5.0 3.4 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 CDJ64111.1 - 6.7 6.7 5.0 6.7 6.7 1.1 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2367 PF10164.9 CDJ64111.1 - 9.4 6.8 10.0 7 7.2 4.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) Lin-8 PF03353.15 CDJ64112.1 - 3e-05 23.8 14.5 3e-05 23.8 14.5 3.2 3 0 0 3 3 3 1 Ras-mediated vulval-induction antagonist PNISR PF15996.5 CDJ64112.1 - 0.00079 19.8 13.3 0.00079 19.8 13.3 3.0 4 0 0 4 4 2 1 Arginine/serine-rich protein PNISR SART-1 PF03343.13 CDJ64112.1 - 0.05 12.2 29.8 0.011 14.4 20.1 2.1 2 0 0 2 2 2 0 SART-1 family HAD PF12710.7 CDJ64112.1 - 0.11 12.8 2.2 20 5.5 0.0 3.4 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase Caldesmon PF02029.15 CDJ64112.1 - 0.3 9.8 25.7 0.16 10.7 16.4 2.1 2 0 0 2 2 2 0 Caldesmon Neur_chan_memb PF02932.16 CDJ64112.1 - 0.32 11.0 26.1 0.97 9.4 21.4 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 CDJ64112.1 - 0.39 9.0 22.8 0.32 9.3 18.8 2.2 2 0 0 2 2 2 0 CDC45-like protein Velvet PF11754.8 CDJ64112.1 - 1 9.2 30.6 2.5 8.0 20.9 3.3 3 0 0 3 3 3 0 Velvet factor RR_TM4-6 PF06459.12 CDJ64112.1 - 1.5 8.6 29.6 0.2 11.5 21.3 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2052 PF09747.9 CDJ64112.1 - 2.2 8.4 29.0 0.53 10.4 21.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) V_ATPase_I PF01496.19 CDJ64112.1 - 2.5 5.9 23.7 9.4 4.0 21.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Gti1_Pac2 PF09729.9 CDJ64112.1 - 2.5 8.2 26.0 1.3 9.1 19.1 2.8 3 0 0 3 3 3 0 Gti1/Pac2 family Tim54 PF11711.8 CDJ64112.1 - 2.9 6.6 21.7 3.3 6.4 16.0 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4638 PF15472.6 CDJ64112.1 - 5.2 6.7 20.0 25 4.5 17.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) AAA_11 PF13086.6 CDJ64112.1 - 5.8 6.6 29.8 4.1 7.1 24.5 2.3 2 0 0 2 2 2 0 AAA domain Presenilin PF01080.17 CDJ64112.1 - 5.9 5.6 39.2 0.79 8.4 29.6 2.6 3 0 0 3 3 3 0 Presenilin DUF2828 PF11443.8 CDJ64112.1 - 6.4 4.7 23.9 3.7 5.5 19.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) FAM60A PF15396.6 CDJ64112.1 - 6.5 6.7 22.1 5.3 7.0 17.3 2.5 2 0 0 2 2 2 0 Protein Family FAM60A Slu7 PF11708.8 CDJ64112.1 - 8.5 6.0 30.2 9.4 5.9 23.3 2.6 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor DUF913 PF06025.12 CDJ64112.1 - 9.9 5.0 16.3 2.3 7.1 11.9 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Pkinase PF00069.25 CDJ64113.1 - 1.6e-29 103.1 0.0 2e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ64113.1 - 5.7e-17 61.9 0.2 7.3e-17 61.5 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ64113.1 - 0.00026 21.0 0.6 0.046 13.6 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ64113.1 - 0.027 14.1 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 AP2 PF00847.20 CDJ64114.1 - 0.00028 21.0 1.5 0.0008 19.6 1.5 1.9 1 0 0 1 1 1 1 AP2 domain Peptidase_S8 PF00082.22 CDJ64115.1 - 4.1e-10 39.4 0.2 6.2e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 Subtilase family Methyltransf_3 PF01596.17 CDJ64116.1 - 0.048 12.8 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.13 CDJ64116.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Serpin PF00079.20 CDJ64117.1 - 1.2e-78 265.1 0.3 1.5e-78 264.7 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) F-box-like PF12937.7 CDJ64119.1 - 0.21 11.5 1.9 1.6 8.7 0.2 2.7 2 0 0 2 2 2 0 F-box-like MORN PF02493.20 CDJ64120.1 - 2.4e-91 294.4 101.0 4.6e-09 35.6 3.0 14.3 14 0 0 14 14 14 14 MORN repeat DEAD PF00270.29 CDJ64121.1 - 1.3e-14 54.3 0.0 1.3e-14 54.3 0.0 1.8 2 0 0 2 2 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ64121.1 - 3.6e-14 53.0 0.0 8.4e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CDJ64121.1 - 7.4e-10 39.4 0.3 7.4e-10 39.4 0.3 3.3 3 0 0 3 3 1 1 RecQ zinc-binding ResIII PF04851.15 CDJ64121.1 - 0.00012 22.1 0.0 0.00012 22.1 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RskA PF10099.9 CDJ64121.1 - 0.0013 19.0 7.6 0.0013 19.0 7.6 11.4 5 4 2 7 7 2 1 Anti-sigma-K factor rskA RQC PF09382.10 CDJ64121.1 - 0.0064 16.3 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 RQC domain AAA_22 PF13401.6 CDJ64121.1 - 0.032 14.5 0.0 0.19 12.0 0.0 2.4 1 0 0 1 1 1 0 AAA domain MCM_lid PF17855.1 CDJ64121.1 - 0.073 13.5 1.2 0.32 11.5 1.2 2.1 1 0 0 1 1 1 0 MCM AAA-lid domain DUF2722 PF10846.8 CDJ64121.1 - 0.085 11.8 44.7 0.061 12.3 20.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) MecA PF05389.12 CDJ64121.1 - 0.95 9.1 9.1 6.9 6.2 0.5 2.4 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF5327 PF17261.2 CDJ64121.1 - 1.8 9.4 28.1 1.5 9.6 2.6 4.2 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Thymidylate_kin PF02223.17 CDJ64121.1 - 2.4 7.8 7.3 0.18 11.5 0.6 2.2 2 0 0 2 2 2 0 Thymidylate kinase eIF-3_zeta PF05091.12 CDJ64121.1 - 7.5 5.4 18.7 7.2 5.5 2.5 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4471 PF14740.6 CDJ64121.1 - 8.6 5.5 12.7 6.8 5.8 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Helicase_C_2 PF13307.6 CDJ64122.1 - 2.9e-40 138.2 0.1 2.9e-40 138.2 0.1 3.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDJ64122.1 - 3.5e-25 88.6 9.7 5.8e-20 71.6 0.1 3.5 3 0 0 3 3 3 2 DEAD_2 CDC73_C PF05179.14 CDJ64123.1 - 3.6e-33 114.5 0.0 5.8e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal DUF1635 PF07795.11 CDJ64123.1 - 0.83 9.5 0.0 0.83 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF1645 PF07816.11 CDJ64123.1 - 9.2 6.8 15.7 0.29 11.7 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) TRAPP PF04051.16 CDJ64125.1 - 4.9e-31 107.4 0.0 2.1e-30 105.4 0.0 1.8 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component TFIIA PF03153.13 CDJ64125.1 - 7.7 6.4 9.0 0.78 9.7 4.6 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RdRP PF05183.12 CDJ64127.1 - 6e-19 68.1 0.0 8.5e-16 57.7 0.0 2.0 1 1 1 2 2 2 2 RNA dependent RNA polymerase DUF4148 PF13663.6 CDJ64127.1 - 0.0091 16.2 4.7 0.0091 16.2 4.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4148) Peptidase_M18 PF02127.15 CDJ64127.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) DUF4651 PF15513.6 CDJ64128.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) RRM_1 PF00076.22 CDJ64128.1 - 0.084 12.7 0.2 1.5 8.7 0.0 2.9 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.27 CDJ64129.1 - 7.7e-14 51.7 0.2 7.7e-14 51.7 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDJ64129.1 - 5.9e-11 42.4 0.0 1.3e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 AAA PF00004.29 CDJ64129.1 - 0.11 12.9 0.1 0.36 11.3 0.1 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CDJ64129.1 - 0.29 11.0 3.3 0.41 10.5 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 CDJ64129.1 - 0.37 10.3 1.2 0.45 10.1 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Abhydrolase_2 PF02230.16 CDJ64130.1 - 1.1e-37 130.0 0.0 1.7e-36 126.1 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CDJ64130.1 - 6.8e-09 35.7 0.0 1.2e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 CDJ64130.1 - 2.4e-06 28.3 0.2 3.8e-06 27.7 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDJ64130.1 - 0.00025 21.0 0.2 0.00055 19.8 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ64130.1 - 0.0025 17.3 0.4 1.9 7.9 0.0 2.6 1 1 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CDJ64130.1 - 0.012 14.8 0.3 0.52 9.5 0.0 2.5 2 1 1 3 3 3 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 CDJ64130.1 - 0.02 14.5 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase_phd PF10503.9 CDJ64130.1 - 0.027 14.0 0.2 0.13 11.7 0.0 1.8 1 1 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 CDJ64130.1 - 0.028 14.1 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 CDJ64130.1 - 0.096 11.2 0.0 0.18 10.2 0.0 1.3 1 1 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Pkinase PF00069.25 CDJ64131.1 - 1e-76 257.8 0.0 1.3e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ64131.1 - 1.4e-34 119.6 0.0 2e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ64131.1 - 1.3e-27 93.3 8.8 7.1e-07 28.3 0.0 4.9 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ64131.1 - 2.9e-24 85.3 3.0 8.2e-13 48.6 1.4 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ64131.1 - 2.8e-23 81.5 10.2 1.5e-07 31.1 1.3 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ64131.1 - 8.9e-23 78.2 8.0 7.2e-06 25.5 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CDJ64131.1 - 7.1e-22 75.9 9.9 4e-07 29.2 0.1 4.9 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.6 CDJ64131.1 - 3.5e-07 30.4 0.4 0.0021 18.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDJ64131.1 - 1.6e-05 24.8 1.5 0.12 12.4 0.6 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.6 CDJ64131.1 - 6.2e-05 22.4 0.0 0.0042 16.4 0.0 2.3 1 1 1 2 2 2 1 Kinase-like SPARC_Ca_bdg PF10591.9 CDJ64131.1 - 9.6e-05 22.7 0.2 0.33 11.3 0.0 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.23 CDJ64131.1 - 0.013 15.5 2.3 0.11 12.4 0.0 3.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family ABC1 PF03109.16 CDJ64131.1 - 0.05 13.8 0.0 0.38 10.9 0.0 2.2 2 0 0 2 2 2 0 ABC1 family Kdo PF06293.14 CDJ64131.1 - 0.078 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPX PF03105.19 CDJ64134.1 - 1.2e-10 41.9 13.5 0.12 12.3 3.8 6.1 3 2 0 4 4 4 4 SPX domain GCV_H PF01597.19 CDJ64135.1 - 7.7e-22 77.5 0.0 3.3e-17 62.5 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CDJ64135.1 - 0.0019 18.0 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme SPX PF03105.19 CDJ64135.1 - 2.5 7.9 9.9 3.5 7.5 9.9 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ64135.1 - 2.8 6.7 9.0 3.5 6.4 9.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain WBP-1 PF11669.8 CDJ64136.1 - 0.22 12.2 0.0 0.22 12.2 0.0 4.5 4 1 0 4 4 4 0 WW domain-binding protein 1 PPL5 PF18168.1 CDJ64137.1 - 4.5 6.5 10.0 0.49 9.6 3.1 2.8 3 1 0 3 3 3 0 Prim-pol family 5 RabGAP-TBC PF00566.18 CDJ64138.1 - 1.2e-41 142.7 6.1 8.4e-41 140.0 4.6 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Use1 PF09753.9 CDJ64138.1 - 0.23 11.2 2.7 0.47 10.1 2.7 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 PHM7_cyt PF14703.6 CDJ64138.1 - 3.8 7.7 7.2 1.6 9.0 3.7 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter SUIM_assoc PF16619.5 CDJ64139.1 - 0.0017 18.4 5.3 0.98 9.5 5.3 2.2 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 HI0933_like PF03486.14 CDJ64139.1 - 0.0097 14.6 0.6 0.012 14.4 0.6 1.0 1 0 0 1 1 1 1 HI0933-like protein Bclx_interact PF08945.10 CDJ64141.1 - 0.21 11.4 0.8 0.62 9.9 0.3 2.0 1 1 0 1 1 1 0 Bcl-x interacting, BH3 domain Ribosomal_S8e PF01201.22 CDJ64142.1 - 1.3e-52 177.6 0.1 1.5e-52 177.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DNA_repr_REX1B PF14966.6 CDJ64143.1 - 0.028 15.1 1.6 0.028 15.1 1.6 3.3 3 1 0 4 4 4 0 DNA repair REX1-B Myosin_head PF00063.21 CDJ64145.1 - 1.6e-12 46.5 25.9 1.4e-06 26.8 0.1 4.7 2 2 1 3 3 3 2 Myosin head (motor domain) SUIM_assoc PF16619.5 CDJ64145.1 - 0.00046 20.2 1.2 0.00046 20.2 1.2 6.7 2 2 2 4 4 2 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ64145.1 - 0.00054 20.3 39.7 0.0011 19.3 24.1 6.2 3 2 1 4 4 2 2 Anti-sigma-K factor rskA ASC PF00858.24 CDJ64145.1 - 0.0014 17.7 0.1 0.0026 16.8 0.1 1.4 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Lin-8 PF03353.15 CDJ64145.1 - 0.0018 17.9 6.5 0.0018 17.9 6.5 2.5 2 1 0 2 2 1 1 Ras-mediated vulval-induction antagonist DAG_kinase_N PF14513.6 CDJ64145.1 - 0.009 16.2 9.7 0.009 16.2 9.7 2.9 2 1 0 2 2 1 1 Diacylglycerol kinase N-terminus Pex14_N PF04695.13 CDJ64145.1 - 0.011 16.4 13.4 0.011 16.4 13.4 4.7 4 1 0 4 4 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gti1_Pac2 PF09729.9 CDJ64145.1 - 0.082 13.0 20.9 1 9.4 1.9 2.6 2 0 0 2 2 2 0 Gti1/Pac2 family Eapp_C PF10238.9 CDJ64145.1 - 0.11 12.6 24.4 0.55 10.3 8.6 3.6 3 0 0 3 3 3 0 E2F-associated phosphoprotein DUF5523 PF17661.1 CDJ64145.1 - 0.24 11.0 27.9 0.22 11.2 14.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5523) EPL1 PF10513.9 CDJ64145.1 - 0.24 11.7 30.4 0.74 10.2 11.5 3.5 3 0 0 3 3 3 0 Enhancer of polycomb-like UPF0560 PF10577.9 CDJ64145.1 - 0.52 8.8 44.0 1.2 7.5 3.6 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0560 Otopetrin PF03189.13 CDJ64145.1 - 0.82 8.4 10.0 3.6 6.3 4.1 2.2 2 0 0 2 2 2 0 Otopetrin PAT1 PF09770.9 CDJ64145.1 - 0.83 7.8 49.1 1.2 7.3 21.9 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 CDJ64145.1 - 1.2 8.1 34.3 1 8.3 15.9 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 CDJ64145.1 - 1.2 8.5 29.6 0.43 10.0 13.4 3.2 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) RPN2_C PF18004.1 CDJ64145.1 - 1.4 8.8 21.3 0.27 11.1 7.2 3.4 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain Suf PF05843.14 CDJ64145.1 - 2 8.4 41.6 1.2 9.1 6.9 3.5 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) CTU2 PF10288.9 CDJ64145.1 - 2.8 8.2 26.7 2.8 8.2 0.8 3.6 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 SLC12 PF03522.15 CDJ64145.1 - 4 6.4 26.1 2.9 6.8 4.7 2.2 2 0 0 2 2 2 0 Solute carrier family 12 DUF1764 PF08576.10 CDJ64145.1 - 5.8 7.9 22.5 18 6.3 0.1 3.6 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) RPA43_OB PF17875.1 CDJ64145.1 - 8.3 7.1 19.5 27 5.4 0.1 3.6 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Shadoo PF14999.6 CDJ64146.1 - 0.017 15.2 0.1 0.02 15.0 0.1 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Trp_oprn_chp PF09534.10 CDJ64146.1 - 0.034 13.9 5.5 0.047 13.5 5.5 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RskA PF10099.9 CDJ64146.1 - 0.33 11.2 25.9 4.2 7.6 25.9 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA B12D PF06522.11 CDJ64146.1 - 0.72 9.7 0.0 0.72 9.7 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Presenilin PF01080.17 CDJ64146.1 - 2.6 6.7 25.8 3.1 6.5 25.8 1.1 1 0 0 1 1 1 0 Presenilin Renin_r PF07850.14 CDJ64146.1 - 4.8 7.9 13.4 0.88 10.2 1.7 2.1 2 0 0 2 2 2 0 Renin receptor-like protein DUF4834 PF16118.5 CDJ64146.1 - 7.6 7.6 31.1 3.5 8.6 10.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) BAF1_ABF1 PF04684.13 CDJ64146.1 - 8.9 5.2 23.4 11 4.9 23.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Caldesmon PF02029.15 CDJ64147.1 - 0.00026 19.9 17.4 0.00026 19.9 17.4 2.5 2 0 0 2 2 2 1 Caldesmon RskA PF10099.9 CDJ64147.1 - 0.0039 17.5 6.7 0.0039 17.5 6.7 8.8 2 2 4 7 7 7 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ64147.1 - 0.0045 16.0 1.3 0.0045 16.0 1.3 5.2 4 1 1 5 5 5 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ64147.1 - 0.0069 16.0 5.1 0.0069 16.0 5.1 4.6 4 1 1 5 5 5 1 Spt20 family SUIM_assoc PF16619.5 CDJ64147.1 - 0.075 13.1 0.1 0.075 13.1 0.1 8.0 3 2 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 GYF PF02213.16 CDJ64148.1 - 4.4e-13 48.7 1.4 1.1e-12 47.4 1.4 1.7 1 0 0 1 1 1 1 GYF domain RskA PF10099.9 CDJ64148.1 - 3.8e-06 27.3 0.3 3.8e-06 27.3 0.3 11.8 2 2 3 6 6 6 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ64148.1 - 9.3e-06 25.4 6.2 9.3e-06 25.4 6.2 8.0 6 2 2 8 8 8 2 Nuclear RNA-splicing-associated protein DUF1053 PF06327.14 CDJ64149.1 - 0.0092 16.5 1.4 0.089 13.4 0.0 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1053) DUF2722 PF10846.8 CDJ64149.1 - 0.037 13.0 0.4 0.043 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ64149.1 - 1.1 8.8 9.8 1.6 8.3 9.8 1.1 1 0 0 1 1 1 0 Spt20 family TCP PF03634.13 CDJ64150.1 - 0.015 15.9 12.5 0.015 15.9 12.5 3.3 3 0 0 3 3 3 0 TCP family transcription factor TBP PF00352.21 CDJ64151.1 - 1.4e-17 63.4 0.0 5.8e-10 39.0 0.0 2.7 2 1 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF2722 PF10846.8 CDJ64151.1 - 0.0031 16.5 3.7 0.0031 16.5 3.7 5.2 2 1 2 4 4 4 1 Protein of unknown function (DUF2722) DUF4775 PF16001.5 CDJ64153.1 - 0.0071 15.8 2.2 0.011 15.2 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4775) MAP65_ASE1 PF03999.12 CDJ64153.1 - 0.36 9.5 9.9 0.51 9.0 9.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TFIIA PF03153.13 CDJ64153.1 - 1.3 8.9 14.5 1.8 8.5 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FtsX PF02687.21 CDJ64153.1 - 8.6 6.9 13.9 0.99 9.9 8.2 2.4 2 1 0 2 2 2 0 FtsX-like permease family eIF-3_zeta PF05091.12 CDJ64153.1 - 8.7 5.2 11.1 12 4.7 11.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2722 PF10846.8 CDJ64153.1 - 9.7 5.0 16.9 15 4.4 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Rhabdo_M2 PF04785.12 CDJ64154.1 - 0.018 14.4 0.2 0.033 13.5 0.2 1.4 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 SDA1 PF05285.12 CDJ64154.1 - 0.81 9.0 27.6 1.7 8.0 27.5 1.4 1 1 0 1 1 1 0 SDA1 Baculo_PP31 PF05311.11 CDJ64154.1 - 5.9 6.3 23.3 1.2 8.5 18.2 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Flavodoxin_1 PF00258.25 CDJ64155.1 - 1.4e-05 25.3 0.0 0.53 10.5 0.0 3.7 2 0 0 2 2 2 2 Flavodoxin Spt20 PF12090.8 CDJ64155.1 - 0.18 11.4 5.6 0.6 9.7 5.6 1.9 1 0 0 1 1 1 0 Spt20 family AroM PF07302.11 CDJ64156.1 - 0.0032 16.9 1.5 0.0032 16.9 1.5 1.5 1 1 0 1 1 1 1 AroM protein CPSF100_C PF13299.6 CDJ64156.1 - 0.0054 16.9 0.7 0.007 16.6 0.7 1.1 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal ADP_ribosyl_GH PF03747.14 CDJ64156.1 - 0.043 13.5 5.2 0.043 13.6 5.2 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase RskA PF10099.9 CDJ64156.1 - 0.064 13.6 12.9 0.071 13.4 12.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Gcd10p PF04189.13 CDJ64156.1 - 0.099 11.7 0.1 0.11 11.6 0.1 1.0 1 0 0 1 1 1 0 Gcd10p family NUDIX PF00293.28 CDJ64157.1 - 5.7e-05 23.2 2.9 0.018 15.1 0.0 3.2 3 0 0 3 3 3 2 NUDIX domain CNDH2_C PF16858.5 CDJ64157.1 - 0.17 11.7 10.2 0.27 11.0 10.2 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BTP PF05232.12 CDJ64157.1 - 0.24 11.5 3.4 0.52 10.4 3.4 1.6 1 0 0 1 1 1 0 Chlorhexidine efflux transporter PAT1 PF09770.9 CDJ64157.1 - 7.1 4.8 19.4 9.6 4.3 19.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA PF00004.29 CDJ64158.1 - 1.8e-18 67.2 0.0 1.8e-18 67.2 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CDJ64158.1 - 0.038 14.1 1.3 0.15 12.1 0.0 2.4 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ64158.1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.4 1 1 0 2 2 2 0 AAA domain IER PF05760.12 CDJ64158.1 - 3.1 8.0 38.7 0.067 13.5 17.8 2.1 1 1 1 2 2 2 0 Immediate early response protein (IER) PAT1 PF09770.9 CDJ64158.1 - 8 4.6 31.6 11 4.2 31.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OMPdecase PF00215.24 CDJ64158.1 - 10 5.7 18.0 1.3 8.6 13.4 1.8 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF3395 PF11875.8 CDJ64159.1 - 7e-13 48.7 0.3 1.3e-12 47.9 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) SSTK-IP PF15836.5 CDJ64159.1 - 0.036 14.2 0.2 0.045 13.9 0.2 1.1 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein DnaJ PF00226.31 CDJ64160.1 - 9.2e-11 41.7 0.2 1.6e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain EF-hand_5 PF13202.6 CDJ64161.1 - 7.3e-06 25.3 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CDJ64161.1 - 0.00028 21.3 0.0 0.00039 20.8 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ64161.1 - 0.00037 19.8 0.0 0.00054 19.3 0.0 1.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CDJ64161.1 - 0.0011 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CDJ64161.1 - 0.5 10.7 0.1 0.5 10.7 0.1 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4207 PF13904.6 CDJ64161.1 - 1.2 8.8 31.2 6.6 6.3 31.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) TSA PF03249.13 CDJ64161.1 - 1.3 7.7 7.8 2.3 6.9 7.8 1.3 1 0 0 1 1 1 0 Type specific antigen PPP4R2 PF09184.11 CDJ64161.1 - 6.4 6.3 16.3 7.9 6.0 16.3 1.1 1 0 0 1 1 1 0 PPP4R2 Sel1 PF08238.12 CDJ64162.1 - 0.00022 21.8 2.8 0.0086 16.7 0.1 3.4 3 1 0 3 3 3 1 Sel1 repeat TFIIA PF03153.13 CDJ64162.1 - 0.00022 21.3 92.3 0.0015 18.6 73.3 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit RCR PF12273.8 CDJ64162.1 - 0.017 15.8 14.3 0.017 15.8 14.3 3.3 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red Trypan_PARP PF05887.11 CDJ64162.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NARP1 PF12569.8 CDJ64162.1 - 2.2 7.1 21.6 4.7 6.0 21.6 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Asp-B-Hydro_N PF05279.11 CDJ64162.1 - 8.4 6.4 21.0 0.89 9.6 16.5 1.7 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region SUIM_assoc PF16619.5 CDJ64163.1 - 1.5e-07 31.3 5.9 0.00025 21.0 1.5 4.6 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ64163.1 - 0.001 19.4 41.3 0.0031 17.8 17.6 2.4 2 1 0 2 2 2 2 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ64163.1 - 0.12 12.4 32.1 0.18 11.8 32.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mit_KHE1 PF10173.9 CDJ64163.1 - 0.17 11.9 2.2 0.26 11.3 2.2 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Macoilin PF09726.9 CDJ64163.1 - 0.2 10.1 14.2 0.41 9.2 14.2 1.4 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 CDJ64163.1 - 0.22 11.1 14.2 0.32 10.5 14.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ64163.1 - 4.9 5.9 14.6 8.5 5.1 14.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1645 PF07816.11 CDJ64164.1 - 0.0012 19.5 8.8 0.0012 19.5 8.8 5.4 2 2 1 5 5 3 1 Protein of unknown function (DUF1645) RskA PF10099.9 CDJ64164.1 - 0.0029 17.9 9.5 0.0029 17.9 9.5 5.9 1 1 2 3 3 1 1 Anti-sigma-K factor rskA Spore_YhcN_YlaJ PF09580.10 CDJ64164.1 - 0.0064 16.6 10.1 0.61 10.1 0.9 3.1 3 0 0 3 3 3 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) HNOBA PF07701.14 CDJ64164.1 - 0.014 14.8 16.6 0.17 11.3 0.5 3.4 3 0 0 3 3 3 0 Heme NO binding associated MecA PF05389.12 CDJ64164.1 - 0.051 13.2 21.6 0.93 9.1 1.6 3.4 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) DUF5523 PF17661.1 CDJ64164.1 - 0.061 13.0 21.6 1.6 8.4 1.7 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5523) MPM1 PF17234.2 CDJ64164.1 - 0.069 13.4 33.3 1.6 9.0 6.9 3.8 3 0 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 Lipase_GDSL PF00657.22 CDJ64164.1 - 0.14 12.1 10.3 2.4 8.1 0.1 3.2 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase rRNA_processing PF08524.11 CDJ64164.1 - 0.16 12.0 37.1 1.2 9.1 3.4 4.4 5 0 0 5 5 5 0 rRNA processing eIF-3_zeta PF05091.12 CDJ64164.1 - 0.19 10.7 30.1 0.52 9.2 8.5 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tim54 PF11711.8 CDJ64164.1 - 0.57 8.9 19.5 0.76 8.5 4.5 3.5 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 LMBR1 PF04791.16 CDJ64164.1 - 0.63 8.9 11.8 0.22 10.4 3.7 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein G0-G1_switch_2 PF15103.6 CDJ64164.1 - 0.72 10.3 20.5 9.8 6.7 0.9 3.9 3 0 0 3 3 3 0 G0/G1 switch protein 2 DUF4770 PF15994.5 CDJ64164.1 - 1.7 8.8 36.1 3 8.1 10.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) Connexin PF00029.19 CDJ64164.1 - 2 8.1 15.4 10 5.8 0.3 3.3 3 0 0 3 3 3 0 Connexin RPN2_C PF18004.1 CDJ64164.1 - 2.5 8.0 21.9 6.1 6.7 0.2 3.7 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain Afi1 PF07792.12 CDJ64164.1 - 3.4 8.2 24.6 4.8 7.7 4.9 3.6 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3381 PF11861.8 CDJ64164.1 - 4.3 7.1 32.0 1.5 8.6 1.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) MAT1 PF06391.13 CDJ64164.1 - 6.8 6.5 36.7 3.5 7.4 4.0 3.4 3 0 0 3 3 3 0 CDK-activating kinase assembly factor MAT1 HRDC PF00570.23 CDJ64166.1 - 1.2e-05 25.2 0.3 1.8e-05 24.6 0.3 1.3 1 0 0 1 1 1 1 HRDC domain RskA PF10099.9 CDJ64167.1 - 3.2e-05 24.3 16.2 0.00038 20.8 6.9 2.5 2 0 0 2 2 2 2 Anti-sigma-K factor rskA DUF3446 PF11928.8 CDJ64167.1 - 0.0095 16.2 10.1 0.0095 16.2 10.1 3.3 3 0 0 3 3 3 1 Early growth response N-terminal domain Spt20 PF12090.8 CDJ64167.1 - 0.065 12.8 3.4 0.11 12.1 3.4 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ64167.1 - 0.26 11.3 6.1 0.07 13.1 2.6 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ64167.1 - 0.31 10.6 3.0 0.46 10.0 3.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ribosomal_60s PF00428.19 CDJ64167.1 - 0.8 10.3 31.4 0.097 13.3 2.4 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein GREB1 PF15782.5 CDJ64167.1 - 2 5.4 4.4 2.7 5.0 4.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SUIM_assoc PF16619.5 CDJ64167.1 - 5.3 7.2 12.5 2.1 8.5 9.0 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF89 PF01937.19 CDJ64169.1 - 3.4e-27 95.3 5.2 6.6e-27 94.4 5.1 1.4 1 1 0 1 1 1 1 Protein of unknown function DUF89 TFIIA PF03153.13 CDJ64169.1 - 0.0011 19.1 20.6 0.0015 18.6 20.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Menin PF05053.13 CDJ64169.1 - 0.073 11.4 5.5 0.097 11.0 5.5 1.0 1 0 0 1 1 1 0 Menin DUF4718 PF15842.5 CDJ64169.1 - 0.073 12.9 3.5 0.17 11.6 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) GREB1 PF15782.5 CDJ64169.1 - 0.18 8.9 8.6 0.22 8.6 8.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hydin_ADK PF17213.3 CDJ64169.1 - 0.18 12.1 4.6 0.33 11.2 4.6 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF3446 PF11928.8 CDJ64169.1 - 0.27 11.6 10.8 0.088 13.1 5.3 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain CCB2_CCB4 PF11152.8 CDJ64169.1 - 0.53 9.6 0.0 0.53 9.6 0.0 2.7 2 1 1 3 3 3 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 DUF572 PF04502.13 CDJ64169.1 - 0.68 9.5 6.3 0.9 9.1 6.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MMR1 PF08505.10 CDJ64169.1 - 0.73 10.1 9.8 1.1 9.5 9.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Thioredoxin_4 PF13462.6 CDJ64169.1 - 2.2 8.4 8.5 3.9 7.6 8.5 1.3 1 0 0 1 1 1 0 Thioredoxin DUF1645 PF07816.11 CDJ64169.1 - 3.6 8.1 12.7 4 8.0 11.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) Presenilin PF01080.17 CDJ64169.1 - 6.3 5.5 7.9 9.1 4.9 7.9 1.2 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ64170.1 - 0.0067 16.1 24.7 0.013 15.2 3.3 3.2 2 1 1 3 3 3 3 Nuclear RNA-splicing-associated protein MMR1 PF08505.10 CDJ64172.1 - 0.00031 21.1 28.4 0.00035 20.9 28.4 1.0 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein SART-1 PF03343.13 CDJ64172.1 - 0.0052 15.4 14.4 0.0059 15.2 14.4 1.0 1 0 0 1 1 1 1 SART-1 family LNP1 PF15419.6 CDJ64172.1 - 0.0078 16.5 19.5 0.0097 16.1 19.5 1.1 1 0 0 1 1 1 1 Leukemia NUP98 fusion partner 1 SR-25 PF10500.9 CDJ64172.1 - 0.018 14.6 35.2 0.018 14.6 35.2 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Trp_oprn_chp PF09534.10 CDJ64172.1 - 0.024 14.5 0.3 0.03 14.1 0.3 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) V_ATPase_I PF01496.19 CDJ64172.1 - 0.035 12.0 11.8 0.04 11.9 11.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cwf_Cwc_15 PF04889.12 CDJ64172.1 - 0.037 13.8 21.8 0.048 13.4 21.8 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SARAF PF06682.12 CDJ64172.1 - 0.041 13.5 18.1 0.058 13.0 18.1 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Zip PF02535.22 CDJ64172.1 - 0.054 12.7 7.3 0.069 12.4 7.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 CDJ64172.1 - 0.063 13.3 44.8 0.073 13.1 44.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 CDJ64172.1 - 0.089 11.6 21.8 0.11 11.3 21.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCSAP PF15748.5 CDJ64172.1 - 0.094 12.9 20.7 0.11 12.6 20.7 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 CDJ64172.1 - 0.12 11.1 24.2 0.17 10.6 24.2 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ64172.1 - 0.14 10.4 31.7 0.16 10.2 31.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 CDJ64172.1 - 0.17 11.4 28.2 0.24 11.0 28.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GRP PF07172.11 CDJ64172.1 - 0.22 12.2 5.7 1.3 9.8 0.1 2.2 2 0 0 2 2 2 0 Glycine rich protein family SMYLE_N PF18615.1 CDJ64172.1 - 0.3 10.6 15.5 0.4 10.2 15.5 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PA26 PF04636.13 CDJ64172.1 - 0.32 9.9 14.9 0.38 9.6 14.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF572 PF04502.13 CDJ64172.1 - 0.33 10.5 17.5 0.4 10.2 17.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) bMG10 PF17973.1 CDJ64172.1 - 0.38 11.0 8.7 0.76 10.0 4.0 2.1 1 1 1 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain PepSY_TM_like_2 PF16357.5 CDJ64172.1 - 0.41 10.6 7.9 0.5 10.3 7.9 1.2 1 0 0 1 1 1 0 Putative PepSY_TM-like SAPS PF04499.15 CDJ64172.1 - 0.41 9.4 13.8 0.45 9.2 13.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neugrin PF06413.11 CDJ64172.1 - 0.54 10.2 16.1 0.69 9.9 16.1 1.1 1 0 0 1 1 1 0 Neugrin PAP1 PF08601.10 CDJ64172.1 - 0.61 9.8 24.3 0.76 9.4 24.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF2681 PF10883.8 CDJ64172.1 - 0.62 10.5 30.3 1.4 9.4 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) GREB1 PF15782.5 CDJ64172.1 - 0.79 6.8 31.8 0.87 6.6 31.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S30 PF01577.16 CDJ64172.1 - 0.88 9.1 13.7 1.1 8.8 13.7 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease DUF755 PF05501.11 CDJ64172.1 - 1.3 9.3 46.0 0.038 14.3 34.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) NiFe-hyd_HybE PF11939.8 CDJ64172.1 - 1.4 8.8 11.0 1.8 8.5 11.0 1.2 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE CSG2 PF16965.5 CDJ64172.1 - 2.4 7.0 7.7 3.3 6.6 7.7 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator RskA PF10099.9 CDJ64172.1 - 2.5 8.3 23.0 2.7 8.3 5.1 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Neur_chan_memb PF02932.16 CDJ64172.1 - 3.5 7.6 17.7 4.2 7.4 17.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AF-4 PF05110.13 CDJ64172.1 - 3.6 5.5 38.7 5.1 5.0 38.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein KfrA_N PF11740.8 CDJ64172.1 - 4.5 8.0 28.9 6.2 7.5 28.9 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Vps39_1 PF10366.9 CDJ64172.1 - 5.3 7.4 9.4 3 8.2 5.7 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Hid1 PF12722.7 CDJ64172.1 - 5.4 5.0 22.8 5.7 4.9 22.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DivIC PF04977.15 CDJ64172.1 - 5.9 6.7 28.2 3.5 7.5 3.6 2.2 2 0 0 2 2 2 0 Septum formation initiator SLC12 PF03522.15 CDJ64172.1 - 6.7 5.6 21.1 7.9 5.4 21.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2347 PF09804.9 CDJ64172.1 - 7.6 6.0 12.5 9.3 5.7 12.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) GTSE1_N PF15259.6 CDJ64172.1 - 7.7 6.7 23.9 11 6.2 23.9 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 TMEM151 PF14857.6 CDJ64172.1 - 7.8 5.3 12.3 8.2 5.2 12.3 1.2 1 0 0 1 1 1 0 TMEM151 family Herpes_pp85 PF04637.12 CDJ64172.1 - 8 4.8 10.6 8 4.7 10.6 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF2126 PF09899.9 CDJ64172.1 - 8.3 4.3 10.8 10 4.1 10.8 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) TFIIA PF03153.13 CDJ64174.1 - 5.7e-05 23.3 26.3 6.6e-05 23.1 26.3 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CutA1 PF03091.15 CDJ64175.1 - 5.4e-33 112.8 1.8 7.1e-33 112.4 1.8 1.2 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DUF3082 PF11282.8 CDJ64175.1 - 0.04 14.2 0.8 0.065 13.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) CT_C_D PF02682.16 CDJ64175.1 - 0.055 13.2 0.3 0.071 12.8 0.3 1.2 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D SCAPER_N PF16501.5 CDJ64175.1 - 0.089 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 S phase cyclin A-associated protein in the endoplasmic reticulum vATP-synt_E PF01991.18 CDJ64176.1 - 9.7e-60 201.4 2.0 1.2e-59 201.1 2.0 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Helicase_PWI PF18149.1 CDJ64176.1 - 0.02 15.1 3.0 0.047 13.9 3.0 1.6 1 0 0 1 1 1 0 N-terminal helicase PWI domain DUF4239 PF14023.6 CDJ64176.1 - 0.025 14.3 5.2 0.073 12.8 4.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) IL13 PF03487.13 CDJ64176.1 - 0.089 12.6 1.9 0.11 12.2 0.4 1.9 2 0 0 2 2 2 0 Interleukin-13 CemA PF03040.14 CDJ64176.1 - 1.6 8.6 4.3 2.3 8.1 4.3 1.3 1 0 0 1 1 1 0 CemA family Selenoprotein_S PF06936.11 CDJ64176.1 - 6.1 6.6 7.0 10 5.9 7.0 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) TIP120 PF08623.10 CDJ64176.1 - 8.2 6.2 10.4 26 4.6 7.2 2.4 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) PDCD2_C PF04194.13 CDJ64177.1 - 7.2e-35 120.6 0.3 1.9e-33 116.0 0.1 2.2 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Kelch_3 PF13415.6 CDJ64178.1 - 1.8e-16 60.0 1.7 2.7e-06 27.5 0.2 5.1 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ64178.1 - 2e-16 59.5 0.5 0.00079 19.4 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 CDJ64178.1 - 3.2e-12 46.3 7.3 3.1e-05 23.9 0.1 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain HATPase_c_3 PF13589.6 CDJ64178.1 - 1.4e-09 37.9 0.0 2.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_1 PF01344.25 CDJ64178.1 - 9e-05 22.0 0.1 2.6 7.7 0.0 3.9 4 0 0 4 4 4 2 Kelch motif HATPase_c PF02518.26 CDJ64178.1 - 0.00023 21.7 0.0 0.00045 20.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_6 PF13964.6 CDJ64178.1 - 0.0061 16.8 2.9 0.63 10.4 0.1 4.3 2 2 2 4 4 4 1 Kelch motif Ribosomal_S3Ae PF01015.18 CDJ64179.1 - 5.8e-90 300.3 0.1 7.3e-90 300.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 CDJ64179.1 - 0.19 11.3 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Cullin PF00888.22 CDJ64180.1 - 0.012 14.3 0.3 0.017 13.7 0.3 1.1 1 0 0 1 1 1 0 Cullin family Lipase_3 PF01764.25 CDJ64181.1 - 6e-17 61.8 0.0 9.4e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ64181.1 - 0.00054 20.6 0.9 0.00054 20.6 0.9 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ64181.1 - 0.00071 18.9 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 CDJ64181.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase Presenilin PF01080.17 CDJ64181.1 - 0.29 9.9 0.7 0.54 9.0 0.7 1.4 1 0 0 1 1 1 0 Presenilin CUE PF02845.16 CDJ64182.1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 CUE domain Snurportin1 PF11538.8 CDJ64182.1 - 0.045 13.9 0.4 0.15 12.2 0.4 1.9 1 0 0 1 1 1 0 Snurportin1 Kelch_4 PF13418.6 CDJ64183.1 - 3.7e-35 119.7 11.2 1.1e-08 35.0 0.0 6.7 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ64183.1 - 9e-28 95.8 1.4 1.9e-06 27.7 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CDJ64183.1 - 2.8e-24 84.6 1.5 4.1e-07 30.0 0.2 5.4 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 CDJ64183.1 - 1.7e-23 82.4 8.7 7.8e-07 29.2 0.0 7.6 9 0 0 9 9 9 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ64183.1 - 6.9e-18 63.8 12.2 2.3e-05 24.2 0.2 6.6 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 CDJ64183.1 - 1.1e-15 56.9 5.4 4.6e-05 22.9 0.0 5.3 6 0 0 6 6 6 3 Kelch motif DUF4110 PF13422.6 CDJ64183.1 - 4.3e-15 55.6 0.2 4.3e-15 55.6 0.2 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) PIEZO PF15917.5 CDJ64183.1 - 0.96 8.9 9.6 0.053 13.0 3.0 2.1 2 0 0 2 2 2 0 Piezo MA3 PF02847.17 CDJ64185.1 - 1.7e-28 98.8 1.5 1.5e-09 37.8 0.0 3.2 3 0 0 3 3 3 3 MA3 domain DUF445 PF04286.12 CDJ64185.1 - 0.14 11.9 0.0 0.61 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF445) PARP PF00644.20 CDJ64186.1 - 0.0033 17.0 0.0 0.011 15.4 0.0 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF4120 PF13496.6 CDJ64187.1 - 0.032 14.6 0.1 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4120) Pex16 PF08610.10 CDJ64188.1 - 1.9e-26 93.0 1.8 2.3e-25 89.4 1.8 2.1 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Sec7 PF01369.20 CDJ64189.1 - 8.5e-66 221.1 0.0 1.3e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CDJ64189.1 - 8.4e-12 45.3 0.0 2.9e-11 43.5 0.0 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PAZ PF02170.22 CDJ64193.1 - 2.2e-08 34.0 0.1 4e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 PAZ domain Piwi PF02171.17 CDJ64193.1 - 1.3e-07 31.2 0.0 9e-07 28.4 0.0 2.0 2 0 0 2 2 2 1 Piwi domain Herpes_PAP PF03325.13 CDJ64193.1 - 0.19 11.3 0.0 0.44 10.1 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein WGG PF10273.9 CDJ64194.1 - 5.5e-22 78.2 0.7 1.1e-21 77.2 0.7 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Tautomerase_2 PF14552.6 CDJ64194.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme ETF PF01012.21 CDJ64196.1 - 0.037 13.9 0.1 0.068 13.0 0.1 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Spt20 PF12090.8 CDJ64196.1 - 1.2 8.7 12.0 2.8 7.5 12.0 1.5 1 0 0 1 1 1 0 Spt20 family Folliculin PF11704.8 CDJ64196.1 - 2.7 7.9 6.8 0.93 9.4 1.3 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4698 PF15769.5 CDJ64196.1 - 2.9 6.8 11.3 0.1 11.6 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) TPR_2 PF07719.17 CDJ64197.1 - 5.9e-12 44.7 11.9 0.001 19.0 0.3 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ64197.1 - 3.3e-10 39.3 7.3 0.012 15.4 0.8 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ64197.1 - 7.6e-07 28.9 9.2 0.082 13.2 0.3 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ64197.1 - 0.00031 21.3 9.2 0.37 11.7 0.1 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat MIT PF04212.18 CDJ64197.1 - 0.00041 20.4 0.2 0.00041 20.4 0.2 3.3 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 CDJ64197.1 - 0.00047 20.7 7.0 0.19 12.4 0.1 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ64197.1 - 0.00099 18.7 2.3 0.64 9.8 0.1 3.5 3 1 1 4 4 4 1 TPR repeat TPR_6 PF13174.6 CDJ64197.1 - 0.0056 17.2 9.2 4.2 8.2 0.1 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ64197.1 - 0.011 16.1 14.0 0.99 9.7 0.2 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ64197.1 - 0.012 15.7 1.0 0.27 11.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat EcoR124_C PF12008.8 CDJ64197.1 - 0.027 14.1 0.0 0.099 12.3 0.0 1.7 1 1 1 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal TPR_19 PF14559.6 CDJ64197.1 - 0.037 14.6 5.5 2.2 8.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3808 PF10300.9 CDJ64197.1 - 0.064 12.0 3.4 0.092 11.5 2.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3808) HBM PF16591.5 CDJ64197.1 - 0.067 12.6 4.6 0.81 9.1 2.0 2.3 1 1 1 2 2 2 0 Helical bimodular sensor domain Clathrin PF00637.20 CDJ64197.1 - 0.1 12.5 0.0 0.37 10.7 0.0 1.9 1 1 1 2 2 2 0 Region in Clathrin and VPS ANAPC3 PF12895.7 CDJ64197.1 - 0.11 12.8 5.3 2.7 8.3 3.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CDJ64197.1 - 0.12 12.3 2.7 3.9 7.5 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PNMA PF14893.6 CDJ64197.1 - 0.69 9.2 6.1 2.6 7.4 4.3 2.2 1 1 1 2 2 2 0 PNMA BTAD PF03704.17 CDJ64197.1 - 4.1 7.8 9.9 0.36 11.2 4.6 2.0 2 1 1 3 3 2 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 CDJ64197.1 - 5.7 7.9 7.5 8.7 7.3 0.4 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Tir_receptor_N PF07490.11 CDJ64199.1 - 0.0028 17.5 1.4 0.0028 17.5 1.4 2.7 3 0 0 3 3 3 1 Translocated intimin receptor (Tir) N-terminus DUF2722 PF10846.8 CDJ64199.1 - 0.0039 16.2 3.9 0.0039 16.2 3.9 5.5 5 0 0 5 5 5 3 Protein of unknown function (DUF2722) ORC_WH_C PF18137.1 CDJ64199.1 - 0.0041 17.2 16.5 3.6 7.6 0.2 3.8 3 0 0 3 3 3 3 Origin recognition complex winged helix C-terminal MecA PF05389.12 CDJ64199.1 - 0.49 10.0 9.2 5.2 6.6 0.1 3.2 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) Connexin PF00029.19 CDJ64199.1 - 0.61 9.8 8.1 26 4.5 0.0 3.4 3 0 0 3 3 3 0 Connexin SPX PF03105.19 CDJ64199.1 - 1.2 9.0 33.8 0.2 11.6 14.9 3.6 3 1 0 3 3 3 0 SPX domain RskA PF10099.9 CDJ64200.1 - 0.92 9.8 11.9 1.1 9.5 11.9 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DnaJ PF00226.31 CDJ64202.1 - 2.5e-17 62.7 0.1 4.1e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3498 PF12004.8 CDJ64202.1 - 0.15 11.2 7.4 0.17 11.0 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) SARG PF15385.6 CDJ64203.1 - 0.0018 17.6 21.4 0.003 16.9 21.4 1.3 1 0 0 1 1 1 1 Specifically androgen-regulated gene protein Spt20 PF12090.8 CDJ64203.1 - 0.81 9.3 52.9 1.9 8.1 10.5 2.1 2 0 0 2 2 2 0 Spt20 family FAM176 PF14851.6 CDJ64203.1 - 0.87 9.2 9.0 3.4 7.3 5.3 2.1 2 0 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 CDJ64203.1 - 0.98 10.4 21.7 3.9 8.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Rrn6 PF10214.9 CDJ64203.1 - 1.1 7.6 28.9 1.3 7.4 28.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4820 PF16091.5 CDJ64203.1 - 1.4 8.2 13.1 2 7.7 6.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF2098 PF09871.9 CDJ64203.1 - 2.1 8.7 5.4 18 5.8 3.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) RAP1 PF07218.11 CDJ64203.1 - 2.6 6.2 4.6 2.5 6.3 4.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4770 PF15994.5 CDJ64203.1 - 2.7 8.2 18.8 2.8 8.2 12.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) RskA PF10099.9 CDJ64203.1 - 3.9 7.7 49.3 0.045 14.1 34.0 2.2 1 1 0 2 2 2 0 Anti-sigma-K factor rskA eIF_4EBP PF05456.11 CDJ64203.1 - 5.9 6.9 14.6 29 4.6 10.3 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Utp14 PF04615.13 CDJ64203.1 - 6.2 5.3 24.6 7.4 5.0 24.6 1.0 1 0 0 1 1 1 0 Utp14 protein Myc_N PF01056.18 CDJ64203.1 - 7.5 6.3 21.1 14 5.5 4.3 1.5 1 1 1 2 2 2 0 Myc amino-terminal region SR-25 PF10500.9 CDJ64204.1 - 0.02 14.5 24.9 0.027 14.1 24.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ64204.1 - 0.18 12.1 22.4 0.93 9.8 22.4 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ64204.1 - 1.8 9.1 4.0 1.7 9.2 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) BAF1_ABF1 PF04684.13 CDJ64204.1 - 1.9 7.4 17.1 2.1 7.3 17.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Lin-8 PF03353.15 CDJ64204.1 - 3 7.3 23.0 4.3 6.8 23.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Suf PF05843.14 CDJ64204.1 - 3.5 7.5 25.7 4.7 7.1 25.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MarC PF01914.17 CDJ64204.1 - 3.6 6.9 3.7 0.84 9.0 0.1 1.7 1 1 1 2 2 2 0 MarC family integral membrane protein Kinesin_assoc PF16183.5 CDJ64204.1 - 3.8 7.6 5.0 5 7.2 5.0 1.2 1 0 0 1 1 1 0 Kinesin-associated VIR_N PF15912.5 CDJ64205.1 - 7 6.2 0.0 7 6.2 0.0 3.2 4 0 0 4 4 4 0 Virilizer, N-terminal NTP_transf_2 PF01909.23 CDJ64206.1 - 0.0098 16.2 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF3504 PF12012.8 CDJ64206.1 - 0.012 15.5 2.1 0.012 15.5 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) Spt20 PF12090.8 CDJ64206.1 - 0.013 15.1 19.9 0.013 15.1 19.9 3.8 3 1 1 4 4 4 0 Spt20 family MDM31_MDM32 PF08118.11 CDJ64206.1 - 0.16 10.6 0.6 0.33 9.6 0.6 1.6 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins FHIPEP PF00771.20 CDJ64206.1 - 1.8 6.9 5.3 2.7 6.3 5.3 1.3 1 0 0 1 1 1 0 FHIPEP family U1snRNP70_N PF12220.8 CDJ64208.1 - 4.2 8.1 12.4 0.91 10.2 2.2 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Spt20 PF12090.8 CDJ64209.1 - 0.082 12.5 66.8 0.047 13.3 11.8 5.1 5 0 0 5 5 5 0 Spt20 family Filament_head PF04732.14 CDJ64209.1 - 4.5 8.2 33.6 0.92 10.4 10.9 4.0 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region Sec7 PF01369.20 CDJ64210.1 - 3.3e-58 196.4 0.0 5.6e-58 195.6 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CDJ64210.1 - 1.4e-10 41.3 0.0 4.2e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CDJ64210.1 - 8.4e-09 35.2 0.0 3.4e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) SUIM_assoc PF16619.5 CDJ64210.1 - 1.2 9.3 0.0 1.1 9.3 0.6 19.1 15 3 1 16 16 16 0 Unstructured region C-term to UIM in Ataxin3 UCR_UQCRX_QCR9 PF05365.12 CDJ64211.1 - 8.4e-15 54.5 5.2 1.2e-14 54.0 5.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2593 PF10767.9 CDJ64211.1 - 0.033 14.3 0.3 0.035 14.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) Ribosomal_L37 PF08561.10 CDJ64211.1 - 0.17 12.4 0.3 0.2 12.2 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 SNF2_N PF00176.23 CDJ64213.1 - 5.1e-51 173.4 0.0 1.2e-50 172.2 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.29 CDJ64213.1 - 1.5e-20 72.8 81.4 2.1e-10 40.3 6.7 7.1 7 1 0 7 7 7 4 PHD-finger Helicase_C PF00271.31 CDJ64213.1 - 1.2e-12 48.1 0.3 4.8e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ64213.1 - 3e-08 33.8 0.0 7.7e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD_2 PF13831.6 CDJ64213.1 - 0.001 18.5 1.7 0.001 18.5 1.7 6.7 7 0 0 7 7 7 1 PHD-finger PHD_4 PF16866.5 CDJ64213.1 - 0.0011 19.0 58.2 0.012 15.7 5.8 6.7 5 0 0 5 5 5 4 PHD-finger zf-PHD-like PF15446.6 CDJ64213.1 - 0.0039 16.8 1.6 0.0039 16.8 1.6 7.7 6 2 2 8 8 8 4 PHD/FYVE-zinc-finger like domain AAA_14 PF13173.6 CDJ64213.1 - 0.0052 16.8 0.0 0.017 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain C1_1 PF00130.22 CDJ64213.1 - 0.0077 16.1 1.6 0.0077 16.1 1.6 7.6 6 1 1 7 7 7 4 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4710 PF15828.5 CDJ64213.1 - 0.47 10.6 6.6 0.045 13.9 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Nop53 PF07767.11 CDJ64215.1 - 1.8 7.9 19.3 2.1 7.6 19.3 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF5401 PF17380.2 CDJ64215.1 - 2.1 6.3 24.2 2.2 6.3 24.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) SET PF00856.28 CDJ64216.1 - 9e-11 42.4 5.2 1.7e-10 41.5 0.0 3.5 3 2 0 3 3 3 1 SET domain AAA_11 PF13086.6 CDJ64216.1 - 0.015 15.1 2.8 0.04 13.7 2.8 1.7 1 0 0 1 1 1 0 AAA domain HypA PF01155.19 CDJ64216.1 - 0.096 12.7 0.5 0.34 11.0 0.5 1.9 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF759 PF05537.11 CDJ64216.1 - 0.23 10.3 4.4 2.7 6.8 4.1 2.1 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF759) Arm PF00514.23 CDJ64217.1 - 1e-07 31.7 9.8 0.061 13.4 0.0 6.3 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 CDJ64217.1 - 4.4e-06 26.8 0.0 5.4e-05 23.3 0.0 2.5 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.6 CDJ64217.1 - 0.00017 21.9 0.1 0.029 14.7 0.0 3.6 2 1 2 4 4 4 1 HEAT repeats HEAT PF02985.22 CDJ64217.1 - 0.05 13.9 4.2 43 4.8 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat Calpain_inhib PF00748.19 CDJ64217.1 - 0.11 13.0 2.4 0.21 12.1 2.4 1.4 1 0 0 1 1 1 0 Calpain inhibitor Tim17 PF02466.19 CDJ64219.1 - 7.6e-23 81.0 6.5 1.1e-22 80.5 6.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4199 PF13858.6 CDJ64219.1 - 0.13 12.7 0.0 0.18 12.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Phage_holin_3_3 PF16083.5 CDJ64219.1 - 0.13 12.3 6.1 4.1 7.6 0.5 2.7 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III Spectrin_like PF18373.1 CDJ64221.1 - 0.0013 18.7 0.2 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 Spectrin like domain DUF3128 PF11326.8 CDJ64221.1 - 0.026 14.9 0.8 0.066 13.6 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) UvrD-helicase PF00580.21 CDJ64222.1 - 8.8e-47 160.1 0.1 4.4e-42 144.7 0.0 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CDJ64222.1 - 6.7e-30 104.6 0.0 1.8e-18 67.1 0.0 4.9 4 2 0 4 4 4 3 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CDJ64222.1 - 1.7e-20 73.8 0.0 7.1e-20 71.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CDJ64222.1 - 1.2e-09 37.8 0.4 0.00042 20.1 0.0 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Evr1_Alr PF04777.13 CDJ64223.1 - 2.3e-21 76.1 0.0 2.8e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Erv1 / Alr family DHO_dh PF01180.21 CDJ64224.1 - 7.4e-104 347.1 0.0 8.5e-104 346.9 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CDJ64224.1 - 0.0011 18.1 0.3 0.0027 16.8 0.3 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 CDJ64224.1 - 0.052 12.9 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Fusion_gly PF00523.18 CDJ64226.1 - 0.023 13.0 0.5 0.042 12.1 0.5 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 Lip_prot_lig_C PF10437.9 CDJ64226.1 - 0.68 10.0 2.6 15 5.6 0.2 2.5 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus PRKCSH PF07915.13 CDJ64227.1 - 1e-12 48.8 0.0 6e-06 27.2 0.0 2.9 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein YccV-like PF08755.11 CDJ64227.1 - 1e-10 42.0 0.1 1.9e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like PRKCSH_1 PF13015.6 CDJ64227.1 - 8.1e-05 22.3 0.0 0.16 11.6 0.0 2.5 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein Lambda_tail_I PF06805.12 CDJ64228.1 - 0.077 13.4 0.1 0.5 10.7 0.0 2.2 2 1 1 3 3 3 0 Bacteriophage lambda tail assembly protein I ABC_membrane PF00664.23 CDJ64228.1 - 0.5 10.0 2.4 2.3 7.8 0.2 2.4 2 1 1 3 3 3 0 ABC transporter transmembrane region UCH PF00443.29 CDJ64229.1 - 2.4e-37 128.8 0.0 3.8e-36 124.9 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ64229.1 - 2.2e-05 24.2 0.0 2.2e-05 24.2 0.0 3.9 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Fer4_2 PF12797.7 CDJ64229.1 - 0.28 11.3 1.6 0.94 9.7 1.6 1.9 1 0 0 1 1 1 0 4Fe-4S binding domain ABC_tran PF00005.27 CDJ64230.1 - 9.8e-45 152.4 0.8 4.7e-22 79.0 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 CDJ64230.1 - 1.8e-19 70.7 2.4 6.5e-06 26.2 0.1 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 CDJ64230.1 - 3.2e-18 65.5 1.9 3.2e-18 65.5 1.9 3.3 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 CDJ64230.1 - 5e-09 35.9 5.3 0.00027 20.5 0.0 4.2 3 2 1 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ64230.1 - 3.4e-07 29.9 0.3 0.016 15.0 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CDJ64230.1 - 5.8e-07 29.6 2.0 0.13 11.9 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ64230.1 - 3.1e-06 27.2 0.0 0.048 13.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDJ64230.1 - 5.8e-06 26.4 0.0 0.18 11.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 CDJ64230.1 - 1.7e-05 25.0 1.3 0.048 13.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 CDJ64230.1 - 2.6e-05 24.5 0.3 0.05 13.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 CDJ64230.1 - 3.5e-05 23.9 0.1 0.22 11.6 0.0 3.0 3 0 0 3 3 3 2 Dynamin family AAA_18 PF13238.6 CDJ64230.1 - 3.6e-05 24.3 0.5 0.045 14.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain NACHT PF05729.12 CDJ64230.1 - 0.00075 19.4 0.1 1.3 8.9 0.0 3.0 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 CDJ64230.1 - 0.0021 18.4 8.7 0.096 13.0 0.2 4.1 5 1 0 5 5 3 2 AAA domain AAA_24 PF13479.6 CDJ64230.1 - 0.0031 17.3 0.0 1.5 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ64230.1 - 0.0073 16.7 0.6 7.3 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.6 CDJ64230.1 - 0.011 15.8 0.2 10 6.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.22 CDJ64230.1 - 0.013 15.9 0.0 4.4 7.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase MeaB PF03308.16 CDJ64230.1 - 0.017 14.1 0.0 2.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 CDJ64230.1 - 0.025 14.1 0.1 0.79 9.2 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family Septin PF00735.18 CDJ64230.1 - 0.039 13.2 0.2 13 5.0 0.0 2.9 2 1 1 3 3 3 0 Septin DUF3584 PF12128.8 CDJ64230.1 - 0.048 11.2 0.0 0.048 11.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) NTPase_1 PF03266.15 CDJ64230.1 - 0.056 13.4 0.1 17 5.2 0.0 3.2 3 0 0 3 3 3 0 NTPase FtsK_SpoIIIE PF01580.18 CDJ64230.1 - 0.057 12.8 2.2 1.6 8.0 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF87 PF01935.17 CDJ64230.1 - 0.063 13.4 2.7 1.8 8.6 0.0 3.2 4 0 0 4 4 4 0 Helicase HerA, central domain NB-ARC PF00931.22 CDJ64230.1 - 0.067 12.4 0.0 6.9 5.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 CDJ64230.1 - 0.13 12.8 0.2 0.13 12.8 0.2 5.1 4 3 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.17 CDJ64230.1 - 0.14 11.9 0.8 68 3.1 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Seryl_tRNA_N PF02403.22 CDJ64230.1 - 0.19 12.0 0.0 0.19 12.0 0.0 2.7 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain S4 PF01479.25 CDJ64231.1 - 9.9e-05 22.0 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain PseudoU_synth_2 PF00849.22 CDJ64231.1 - 0.0025 17.9 0.0 0.0036 17.4 0.0 1.4 1 1 0 1 1 1 1 RNA pseudouridylate synthase ubiquitin PF00240.23 CDJ64232.1 - 0.0052 16.5 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 CDJ64232.1 - 0.018 15.8 0.0 0.028 15.1 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DUF2340 PF10209.9 CDJ64232.1 - 0.071 13.6 0.2 0.11 13.0 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) zf-met2 PF12907.7 CDJ64233.1 - 1.8e-16 59.9 7.2 2.5e-16 59.5 7.2 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 CDJ64233.1 - 1.3e-07 32.3 8.5 1.9e-07 31.8 8.5 1.3 1 0 0 1 1 1 1 4F5 protein family zf-C2H2_12 PF18658.1 CDJ64233.1 - 0.0092 15.5 1.0 0.013 15.1 1.0 1.2 1 0 0 1 1 1 1 Zinc-finger C2H2-type zf-C2H2_4 PF13894.6 CDJ64233.1 - 0.074 13.9 1.2 0.074 13.9 1.2 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger Gram_pos_anchor PF00746.21 CDJ64234.1 - 0.026 14.5 0.1 0.069 13.1 0.1 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Podoplanin PF05808.11 CDJ64234.1 - 0.082 13.0 0.7 0.082 13.0 0.7 2.2 2 1 0 2 2 2 0 Podoplanin LapA_dom PF06305.11 CDJ64234.1 - 0.46 10.3 3.0 1.6 8.6 0.2 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Patched PF02460.18 CDJ64235.1 - 5.9e-85 286.0 0.0 4.6e-84 283.0 0.0 1.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ64235.1 - 5.2e-26 91.3 23.5 7.1e-25 87.6 1.4 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation PRCC PF10253.9 CDJ64235.1 - 0.0062 17.4 0.3 0.21 12.4 0.0 2.2 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting ACR_tran PF00873.19 CDJ64235.1 - 6.1 4.4 30.2 0.14 9.8 22.4 1.9 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family MtN3_slv PF03083.16 CDJ64236.1 - 6.5e-13 48.5 1.9 7.1e-08 32.4 0.2 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Pex14_N PF04695.13 CDJ64236.1 - 0.0039 17.9 2.1 0.0039 17.9 2.1 2.1 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ64236.1 - 0.022 14.7 2.5 0.028 14.4 2.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Protocadherin PF08374.11 CDJ64236.1 - 0.04 13.9 0.3 0.062 13.3 0.3 1.3 1 0 0 1 1 1 0 Protocadherin DUF3464 PF11947.8 CDJ64236.1 - 0.073 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FAM176 PF14851.6 CDJ64236.1 - 0.16 11.6 0.8 0.32 10.7 0.8 1.4 1 0 0 1 1 1 0 FAM176 family DUF4834 PF16118.5 CDJ64236.1 - 0.53 11.3 4.2 1 10.3 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TERB2 PF15101.6 CDJ64236.1 - 4.7 7.2 8.4 7 6.6 8.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 zf-LSD1 PF06943.12 CDJ64236.1 - 7.9 6.4 10.2 0.83 9.5 3.9 2.6 2 0 0 2 2 2 0 LSD1 zinc finger TFIIA PF03153.13 CDJ64237.1 - 0.037 14.0 17.4 0.044 13.8 17.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ64240.1 - 0.00012 22.5 9.4 0.00012 22.5 9.4 3.8 2 2 0 2 2 1 1 Anti-sigma-K factor rskA SprA-related PF12118.8 CDJ64240.1 - 0.00087 18.5 35.2 0.00087 18.5 35.2 2.4 3 0 0 3 3 3 1 SprA-related family Spt20 PF12090.8 CDJ64240.1 - 0.004 16.8 2.8 0.004 16.8 2.8 3.9 2 1 0 2 2 1 1 Spt20 family DUF2722 PF10846.8 CDJ64240.1 - 0.0065 15.5 1.3 0.0065 15.5 1.3 4.1 2 1 1 3 3 1 1 Protein of unknown function (DUF2722) RIFIN PF02009.16 CDJ64240.1 - 0.053 13.4 21.2 0.069 13.0 18.0 2.0 2 0 0 2 2 2 0 Rifin SAPS PF04499.15 CDJ64240.1 - 0.093 11.5 13.2 0.036 12.9 10.3 1.7 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Raftlin PF15250.6 CDJ64240.1 - 0.096 11.4 30.0 0.13 11.0 23.8 2.1 2 0 0 2 2 2 0 Raftlin PA26 PF04636.13 CDJ64240.1 - 0.14 11.0 15.1 0.026 13.5 9.2 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 CDJ64240.1 - 0.33 9.7 32.9 2.5 6.8 0.1 2.4 2 0 0 2 2 2 0 Presenilin Tmemb_cc2 PF10267.9 CDJ64240.1 - 0.39 9.8 30.7 0.12 11.5 19.0 2.5 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF572 PF04502.13 CDJ64240.1 - 0.57 9.8 25.2 0.86 9.2 21.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) SpoIIIAH PF12685.7 CDJ64240.1 - 3.3 7.5 29.4 2.2 8.1 24.3 2.3 2 1 0 2 2 2 0 SpoIIIAH-like protein RR_TM4-6 PF06459.12 CDJ64240.1 - 3.5 7.4 26.0 1.5 8.6 20.8 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TRAP_alpha PF03896.16 CDJ64241.1 - 0.0073 15.5 5.2 0.0085 15.3 5.2 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit V_ATPase_I PF01496.19 CDJ64241.1 - 0.0095 13.9 15.1 0.0099 13.9 15.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PIP5K PF01504.18 CDJ64241.1 - 0.012 14.8 9.6 0.012 14.8 9.6 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Presenilin PF01080.17 CDJ64241.1 - 0.013 14.3 16.2 0.014 14.2 16.2 1.1 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 CDJ64241.1 - 0.018 14.6 15.9 0.018 14.5 15.9 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CCDC53 PF10152.9 CDJ64241.1 - 0.018 15.4 17.7 0.022 15.2 17.7 1.0 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RR_TM4-6 PF06459.12 CDJ64241.1 - 0.022 14.6 12.1 0.023 14.5 12.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peroxin-13_N PF04088.13 CDJ64241.1 - 0.022 15.0 9.2 0.027 14.7 9.2 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region CPSF100_C PF13299.6 CDJ64241.1 - 0.029 14.6 11.5 0.032 14.4 11.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.13 CDJ64241.1 - 0.032 14.9 26.4 0.036 14.7 26.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ64241.1 - 0.034 13.9 9.9 0.036 13.8 9.9 1.1 1 0 0 1 1 1 0 Connexin Serendipity_A PF05482.12 CDJ64241.1 - 0.038 12.7 6.4 0.041 12.5 6.4 1.0 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) Serinc PF03348.15 CDJ64241.1 - 0.039 12.9 7.9 0.041 12.8 7.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Velvet PF11754.8 CDJ64241.1 - 0.041 13.8 13.7 0.044 13.7 13.7 1.0 1 0 0 1 1 1 0 Velvet factor Peptidase_S49_N PF08496.10 CDJ64241.1 - 0.044 13.9 13.2 0.05 13.7 13.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EIIBC-GUT_N PF03612.14 CDJ64241.1 - 0.047 13.4 12.4 0.051 13.3 12.4 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3408 PF11888.8 CDJ64241.1 - 0.047 13.8 14.0 0.056 13.6 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF2464 PF10240.9 CDJ64241.1 - 0.051 13.1 9.3 0.055 13.0 9.3 1.0 1 0 0 1 1 1 0 Multivesicular body subunit 12 Ureide_permease PF07168.11 CDJ64241.1 - 0.058 12.1 3.7 0.059 12.1 3.7 1.0 1 0 0 1 1 1 0 Ureide permease AIF_C PF14721.6 CDJ64241.1 - 0.068 13.5 11.2 0.085 13.2 11.2 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2828 PF11443.8 CDJ64241.1 - 0.077 11.1 14.9 0.086 10.9 14.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PAT1 PF09770.9 CDJ64241.1 - 0.077 11.3 27.7 0.079 11.2 27.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TERB2 PF15101.6 CDJ64241.1 - 0.08 13.0 21.6 0.088 12.9 21.6 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Peptidase_U57 PF05582.12 CDJ64241.1 - 0.081 12.2 10.4 0.091 12.0 10.4 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF5308 PF17233.2 CDJ64241.1 - 0.081 13.1 11.7 0.095 12.9 11.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Baculo_PP31 PF05311.11 CDJ64241.1 - 0.085 12.3 13.0 0.093 12.2 13.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) eIF-3_zeta PF05091.12 CDJ64241.1 - 0.088 11.8 20.8 0.09 11.7 20.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 CDJ64241.1 - 0.1 11.6 10.5 0.11 11.6 10.5 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4820 PF16091.5 CDJ64241.1 - 0.11 11.9 11.6 0.14 11.5 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Neur_chan_memb PF02932.16 CDJ64241.1 - 0.11 12.6 9.9 0.11 12.5 9.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LpxB PF02684.15 CDJ64241.1 - 0.11 11.3 11.5 0.12 11.1 11.5 1.0 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Band_3_cyto PF07565.13 CDJ64241.1 - 0.11 12.2 15.4 0.12 12.1 15.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.17 CDJ64241.1 - 0.11 12.6 13.9 0.12 12.5 13.9 1.1 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.13 CDJ64241.1 - 0.12 11.3 16.3 0.13 11.3 16.3 1.0 1 0 0 1 1 1 0 Paf1 DcuA_DcuB PF03605.14 CDJ64241.1 - 0.13 11.2 3.7 0.13 11.1 3.7 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Tim54 PF11711.8 CDJ64241.1 - 0.13 11.1 13.3 0.14 10.9 13.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.13 CDJ64241.1 - 0.16 11.9 46.5 0.18 11.8 46.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Endostatin PF06482.11 CDJ64241.1 - 0.19 11.2 14.9 0.21 11.0 14.9 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SID-1_RNA_chan PF13965.6 CDJ64241.1 - 0.21 10.0 7.4 0.21 10.0 7.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3295 PF11702.8 CDJ64241.1 - 0.21 10.9 17.1 0.24 10.7 17.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) FAM60A PF15396.6 CDJ64241.1 - 0.22 11.5 11.9 0.22 11.5 11.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4770 PF15994.5 CDJ64241.1 - 0.24 11.7 15.2 0.3 11.3 15.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Ctr PF04145.15 CDJ64241.1 - 0.28 11.8 7.9 0.31 11.7 7.9 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Gti1_Pac2 PF09729.9 CDJ64241.1 - 0.29 11.2 12.6 0.35 10.9 12.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 CDJ64241.1 - 0.3 10.1 15.7 0.3 10.1 15.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 CDJ64241.1 - 0.42 9.8 9.2 0.48 9.6 9.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CSG2 PF16965.5 CDJ64241.1 - 0.42 9.5 10.5 0.47 9.3 10.5 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Folliculin PF11704.8 CDJ64241.1 - 0.44 10.4 10.3 0.44 10.4 10.3 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport EOS1 PF12326.8 CDJ64241.1 - 0.44 10.5 9.0 0.49 10.3 9.0 1.1 1 0 0 1 1 1 0 N-glycosylation protein Aconitase PF00330.20 CDJ64241.1 - 0.46 9.4 7.4 0.53 9.2 7.4 1.0 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) MDM31_MDM32 PF08118.11 CDJ64241.1 - 0.47 9.1 10.8 0.5 9.0 10.8 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Folate_carrier PF01770.18 CDJ64241.1 - 0.52 9.0 7.1 0.51 9.0 7.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF1764 PF08576.10 CDJ64241.1 - 0.53 11.2 14.2 0.63 11.0 14.2 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF2370 PF10176.9 CDJ64241.1 - 0.57 9.8 7.7 0.6 9.7 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) YABBY PF04690.13 CDJ64241.1 - 0.61 10.6 12.8 0.68 10.5 12.8 1.2 1 0 0 1 1 1 0 YABBY protein DUF1980 PF09323.10 CDJ64241.1 - 0.62 10.0 12.5 0.69 9.8 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Lin-8 PF03353.15 CDJ64241.1 - 0.62 9.6 19.9 0.65 9.5 19.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CobT PF06213.12 CDJ64241.1 - 0.72 9.2 26.7 0.86 8.9 26.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BORG_CEP PF14957.6 CDJ64241.1 - 0.75 11.0 10.3 0.84 10.8 10.3 1.1 1 0 0 1 1 1 0 Cdc42 effector SelP_N PF04592.14 CDJ64241.1 - 0.76 9.1 18.0 0.95 8.8 18.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HCO3_cotransp PF00955.21 CDJ64241.1 - 0.78 8.5 6.9 0.84 8.4 6.9 1.0 1 0 0 1 1 1 0 HCO3- transporter family Hid1 PF12722.7 CDJ64241.1 - 0.8 7.8 15.2 0.86 7.7 15.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF853 PF05872.12 CDJ64241.1 - 0.81 8.2 12.0 0.87 8.1 12.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) EPL1 PF10513.9 CDJ64241.1 - 0.81 10.1 18.7 1 9.7 18.7 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like RICTOR_N PF14664.6 CDJ64241.1 - 0.87 8.5 7.7 0.96 8.4 7.7 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF4746 PF15928.5 CDJ64241.1 - 0.9 8.9 11.3 0.96 8.8 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ALMT PF11744.8 CDJ64241.1 - 1 8.1 12.6 1 8.1 12.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4175 PF13779.6 CDJ64241.1 - 1.8 6.4 41.3 1.8 6.4 41.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Eapp_C PF10238.9 CDJ64241.1 - 1.9 8.5 18.9 2.6 8.1 18.9 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF4011 PF13195.6 CDJ64241.1 - 2.5 8.0 10.8 3.1 7.7 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) MDM10 PF12519.8 CDJ64241.1 - 2.5 6.9 14.6 2.9 6.7 14.6 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PigN PF04987.14 CDJ64241.1 - 2.7 6.8 7.7 2.6 6.8 7.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Membralin PF09746.9 CDJ64241.1 - 3.4 6.6 11.3 3.2 6.7 11.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein FAM176 PF14851.6 CDJ64241.1 - 4.1 7.0 12.7 5 6.8 12.7 1.1 1 0 0 1 1 1 0 FAM176 family DUF702 PF05142.12 CDJ64241.1 - 4.3 7.8 17.7 6.5 7.2 17.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) O-antigen_lig PF13425.6 CDJ64241.1 - 4.3 6.0 8.6 4.7 5.9 8.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Het-C PF07217.11 CDJ64241.1 - 5.2 5.5 12.8 5.6 5.4 12.8 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Cellulose_synt PF03552.14 CDJ64241.1 - 5.4 5.4 7.2 5.9 5.3 7.2 1.0 1 0 0 1 1 1 0 Cellulose synthase GREB1 PF15782.5 CDJ64241.1 - 5.8 3.9 18.4 5.6 3.9 18.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NEMP PF10225.9 CDJ64241.1 - 6.3 6.4 7.5 6.2 6.4 7.5 1.1 1 0 0 1 1 1 0 NEMP family PRC2_HTH_1 PF18118.1 CDJ64241.1 - 6.5 7.6 15.5 8.4 7.3 15.5 1.1 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain MMR1 PF08505.10 CDJ64241.1 - 6.8 6.9 22.3 8.5 6.6 22.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Kei1 PF08552.11 CDJ64241.1 - 6.9 6.5 13.3 8.9 6.1 13.3 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Sec62 PF03839.16 CDJ64241.1 - 7 6.1 14.3 8.5 5.8 14.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Spc7_N PF15402.6 CDJ64241.1 - 7 4.8 18.8 8.3 4.5 18.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4834 PF16118.5 CDJ64241.1 - 7.2 7.6 29.1 58 4.7 29.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Ndc1_Nup PF09531.10 CDJ64241.1 - 7.4 5.1 16.6 8.7 4.9 16.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mem_trans PF03547.18 CDJ64241.1 - 8.2 4.7 5.7 7.7 4.8 5.7 1.1 1 0 0 1 1 1 0 Membrane transport protein ABC2_membrane_2 PF12679.7 CDJ64241.1 - 9.1 5.5 8.5 9.2 5.5 8.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2126 PF09899.9 CDJ64241.1 - 9.2 4.2 15.2 11 4.0 15.2 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Pal1 PF08316.11 CDJ64241.1 - 9.5 7.0 10.6 11 6.8 10.6 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein WD40 PF00400.32 CDJ64242.1 - 2.7e-06 28.0 0.2 0.013 16.3 0.1 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat SDA1 PF05285.12 CDJ64244.1 - 0.27 10.6 8.5 0.51 9.7 8.5 1.4 1 0 0 1 1 1 0 SDA1 Apt1 PF10351.9 CDJ64244.1 - 4.7 5.9 28.9 11 4.7 18.5 3.4 3 0 0 3 3 3 0 Golgi-body localisation protein domain Zip PF02535.22 CDJ64245.1 - 1.9e-17 63.5 34.8 1.2e-14 54.3 34.8 2.8 1 1 0 1 1 1 1 ZIP Zinc transporter Spt20 PF12090.8 CDJ64245.1 - 6 6.4 18.0 0.084 12.5 6.3 2.6 3 0 0 3 3 3 0 Spt20 family DUF3446 PF11928.8 CDJ64246.1 - 0.002 18.4 6.9 0.002 18.4 6.9 1.9 2 0 0 2 2 2 1 Early growth response N-terminal domain Sporozoite_P67 PF05642.11 CDJ64246.1 - 0.044 11.9 1.4 0.078 11.0 1.4 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SR-25 PF10500.9 CDJ64246.1 - 0.065 12.8 18.2 0.062 12.9 13.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2141 PF09912.9 CDJ64246.1 - 5.6 6.9 37.6 17 5.4 0.1 10.2 2 1 5 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2141) DUF4667 PF15700.5 CDJ64246.1 - 6.5 6.8 12.5 0.25 11.4 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Herpes_pp85 PF04637.12 CDJ64246.1 - 9.7 4.5 7.7 14 3.9 7.7 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Use1 PF09753.9 CDJ64247.1 - 0.0088 15.8 12.8 0.017 14.8 12.8 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 CDJ64247.1 - 0.0094 15.9 0.6 0.018 15.0 0.6 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin-6_N PF09177.11 CDJ64247.1 - 0.049 14.2 0.3 0.049 14.2 0.3 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4577 PF15145.6 CDJ64247.1 - 0.052 13.6 0.6 0.091 12.8 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF2218 PF09981.9 CDJ64247.1 - 0.087 13.2 2.2 2.4 8.6 0.6 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) Med15 PF09606.10 CDJ64247.1 - 0.16 10.6 14.9 0.025 13.3 6.2 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PDDEXK_6 PF04720.12 CDJ64247.1 - 0.34 10.8 5.3 0.094 12.7 1.4 1.9 2 0 0 2 2 2 0 PDDEXK-like family of unknown function CCDC-167 PF15188.6 CDJ64247.1 - 2 8.8 10.8 0.61 10.5 6.0 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2722 PF10846.8 CDJ64247.1 - 3.3 6.5 15.1 0.49 9.3 11.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Lin-8 PF03353.15 CDJ64249.1 - 0.069 12.7 24.6 0.093 12.3 9.3 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CbiD PF01888.17 CDJ64249.1 - 0.22 10.8 1.4 0.36 10.1 1.4 1.3 1 0 0 1 1 1 0 CbiD RCDG1 PF15725.5 CDJ64249.1 - 0.83 10.1 10.7 0.35 11.3 6.2 2.6 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein PAT1 PF09770.9 CDJ64249.1 - 0.89 7.8 37.3 1.3 7.2 18.7 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.6 CDJ64249.1 - 1.4 6.7 50.6 1.6 6.6 16.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Cyto_heme_lyase PF01265.17 CDJ64249.1 - 3.2 7.3 20.3 2.8 7.4 0.1 3.1 3 0 0 3 3 3 0 Cytochrome c/c1 heme lyase Band_3_cyto PF07565.13 CDJ64249.1 - 5.6 6.7 17.6 2.4 7.9 4.6 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ64249.1 - 9 4.9 26.7 2.5 6.8 10.7 2.3 2 0 0 2 2 2 0 Presenilin MAP7 PF05672.11 CDJ64253.1 - 0.001 18.8 13.2 0.001 18.8 13.2 8.3 6 2 1 7 7 7 2 MAP7 (E-MAP-115) family adh_short PF00106.25 CDJ64254.1 - 1.8e-33 115.6 1.1 4.2e-33 114.5 1.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ64254.1 - 3.3e-26 92.3 0.7 2.3e-24 86.3 1.7 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 CDJ64254.1 - 4e-18 65.8 0.1 4.1e-15 56.1 0.0 2.9 3 0 0 3 3 3 2 SCP-2 sterol transfer family KR PF08659.10 CDJ64254.1 - 5.5e-12 46.0 0.3 1.1e-11 45.0 0.3 1.5 1 0 0 1 1 1 1 KR domain Spt20 PF12090.8 CDJ64254.1 - 0.11 12.1 0.9 0.19 11.3 0.9 1.4 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ64254.1 - 0.79 9.6 5.9 0.31 11.0 0.6 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nfu_N PF08712.11 CDJ64255.1 - 2e-21 75.8 0.0 4.2e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CDJ64255.1 - 8.8e-07 29.0 0.1 2.5e-06 27.6 0.1 1.7 2 0 0 2 2 2 1 NifU-like domain DUF5022 PF16425.5 CDJ64255.1 - 0.28 10.6 3.5 0.4 10.1 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5022) Sigma70_ner PF04546.13 CDJ64255.1 - 0.97 9.3 12.7 0.34 10.8 4.7 2.1 1 1 1 2 2 2 0 Sigma-70, non-essential region SR-25 PF10500.9 CDJ64256.1 - 0.02 14.5 25.6 0.25 10.9 14.2 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.9 CDJ64256.1 - 0.099 10.9 16.4 0.17 10.1 16.4 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.14 CDJ64256.1 - 0.85 9.5 10.9 2 8.3 10.9 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ64256.1 - 10 4.8 11.8 5.5 5.7 8.7 2.0 2 0 0 2 2 2 0 Presenilin AP2 PF00847.20 CDJ64257.1 - 0.0039 17.4 1.9 0.0039 17.4 1.9 3.1 4 0 0 4 4 4 1 AP2 domain Tic110 PF16940.5 CDJ64257.1 - 0.054 12.0 13.2 0.068 11.7 13.2 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter MscS_TM PF12794.7 CDJ64257.1 - 0.74 8.6 7.2 0.3 9.9 5.1 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Gag_p17 PF00540.18 CDJ64258.1 - 0.23 11.4 0.0 0.23 11.4 0.0 4.7 7 0 0 7 7 7 0 gag gene protein p17 (matrix protein) SOG2 PF10428.9 CDJ64258.1 - 0.28 10.3 46.8 0.057 12.6 38.9 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Gaa1 PF04114.14 CDJ64259.1 - 3.7e-06 26.3 20.6 0.37 9.8 3.7 6.4 4 2 2 6 6 6 4 Gaa1-like, GPI transamidase component Bul1_C PF04426.12 CDJ64259.1 - 0.011 15.2 0.6 0.092 12.1 0.0 2.2 2 0 0 2 2 2 0 Bul1 C terminus Presenilin PF01080.17 CDJ64259.1 - 0.012 14.5 0.0 0.012 14.5 0.0 2.2 3 0 0 3 3 3 0 Presenilin CSG2 PF16965.5 CDJ64259.1 - 0.72 8.7 4.5 0.096 11.6 0.2 1.6 2 0 0 2 2 2 0 Ceramide synthase regulator DUF2207 PF09972.9 CDJ64259.1 - 1.1 8.0 6.5 2.2 7.0 0.0 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1180 PF06679.12 CDJ64260.1 - 0.63 10.4 4.5 0.61 10.5 3.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Pkinase PF00069.25 CDJ64261.1 - 3.9e-22 78.9 0.0 7.7e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ64261.1 - 8e-12 45.1 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ64261.1 - 1.3e-10 41.0 0.0 2.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ64261.1 - 9.1e-05 21.9 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ64261.1 - 0.0014 18.6 1.5 0.0014 18.6 1.5 2.6 3 1 0 3 3 3 1 Phosphotransferase enzyme family PIP49_C PF12260.8 CDJ64261.1 - 0.029 14.0 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 SR-25 PF10500.9 CDJ64261.1 - 0.1 12.2 4.1 0.16 11.5 4.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MoaE PF02391.17 CDJ64261.1 - 0.12 12.6 0.2 0.95 9.8 0.0 2.4 3 0 0 3 3 3 0 MoaE protein Ribosomal_60s PF00428.19 CDJ64261.1 - 0.13 12.8 3.4 0.77 10.4 3.4 2.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.25 CDJ64262.1 - 1.7e-18 66.9 0.0 3.3e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ64262.1 - 5.4e-07 29.2 0.0 9.5e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ64262.1 - 2.9e-06 26.7 0.0 6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ64262.1 - 0.013 14.9 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ64262.1 - 0.088 12.7 0.0 0.088 12.7 0.0 2.9 3 1 1 4 4 4 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDJ64263.1 - 1.1e-15 57.8 0.0 3.3e-15 56.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ64263.1 - 5.3e-05 22.6 0.0 9.5e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ64263.1 - 0.0007 19.0 0.0 0.0019 17.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ64263.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP_bind_1 PF03029.17 CDJ64264.1 - 1.5e-66 224.6 0.0 1.1e-61 208.7 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CDJ64264.1 - 3.3e-05 24.3 2.6 0.0001 22.8 0.0 2.4 2 1 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.6 CDJ64264.1 - 6.5e-05 23.5 0.0 0.00097 19.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDJ64264.1 - 0.00025 21.3 0.0 0.00055 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ribosomal_60s PF00428.19 CDJ64264.1 - 0.00045 20.7 10.9 0.0013 19.3 9.5 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein PduV-EutP PF10662.9 CDJ64264.1 - 0.0016 18.2 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CDJ64264.1 - 0.0035 17.9 0.0 0.0077 16.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter MeaB PF03308.16 CDJ64264.1 - 0.0037 16.3 0.0 0.0062 15.5 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 CDJ64264.1 - 0.0041 17.1 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CDJ64264.1 - 0.0043 16.8 0.0 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ64264.1 - 0.0058 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA12 PF10443.9 CDJ64264.1 - 0.0073 15.1 0.1 0.37 9.5 0.0 2.1 2 0 0 2 2 2 1 RNA12 protein AAA_30 PF13604.6 CDJ64264.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDJ64264.1 - 0.009 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CDJ64264.1 - 0.015 14.4 0.1 0.04 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 CDJ64264.1 - 0.017 15.6 0.0 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ64264.1 - 0.017 15.0 0.0 0.079 12.9 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase CbiA PF01656.23 CDJ64264.1 - 0.023 14.7 0.0 0.028 14.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 CDJ64264.1 - 0.024 14.2 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CDJ64264.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain CLP1_P PF16575.5 CDJ64264.1 - 0.03 14.1 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Cytidylate_kin PF02224.18 CDJ64264.1 - 0.032 14.0 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_33 PF13671.6 CDJ64264.1 - 0.034 14.3 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CDJ64264.1 - 0.04 14.4 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDJ64264.1 - 0.041 14.3 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase FAM176 PF14851.6 CDJ64264.1 - 0.044 13.4 1.6 0.099 12.3 1.6 1.7 1 0 0 1 1 1 0 FAM176 family Zeta_toxin PF06414.12 CDJ64264.1 - 0.053 12.8 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 CDJ64264.1 - 0.072 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_PrkA PF08298.11 CDJ64264.1 - 0.083 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain TsaE PF02367.17 CDJ64264.1 - 0.097 12.7 0.1 0.39 10.7 0.0 2.1 2 1 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 CDJ64264.1 - 0.11 11.6 0.0 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit cobW PF02492.19 CDJ64264.1 - 0.12 12.0 0.0 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 CDJ64264.1 - 0.14 12.2 0.0 6.6 6.8 0.0 2.7 2 1 1 3 3 3 0 Dynamin family Pox_Ag35 PF03286.14 CDJ64264.1 - 0.17 11.7 3.0 0.27 11.0 3.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Gtr1_RagA PF04670.12 CDJ64264.1 - 0.18 11.1 0.0 0.6 9.4 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RRN3 PF05327.11 CDJ64264.1 - 0.28 9.7 4.2 0.38 9.2 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RMI1_N PF08585.12 CDJ64264.1 - 3.9 7.2 4.8 38 3.9 0.0 3.0 1 1 1 2 2 2 0 RecQ mediated genome instability protein DNA_pol_phi PF04931.13 CDJ64264.1 - 9.7 4.1 10.2 14 3.6 10.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi eIF-3_zeta PF05091.12 CDJ64265.1 - 3.8e-141 471.6 0.0 4.8e-141 471.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 CDJ64265.1 - 0.051 13.1 0.2 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Cullin PF00888.22 CDJ64266.1 - 2.7e-31 108.9 24.7 7.6e-25 87.6 11.9 4.9 4 1 0 4 4 4 3 Cullin family RRM_1 PF00076.22 CDJ64267.1 - 4.4e-05 23.2 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF2A PF08662.11 CDJ64267.1 - 0.02 14.8 0.1 0.058 13.3 0.1 1.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A NPIP PF06409.11 CDJ64267.1 - 0.53 9.3 1.8 0.86 8.6 1.8 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Gemini_coat PF00844.18 CDJ64268.1 - 0.28 10.6 0.5 0.55 9.6 0.0 1.7 2 0 0 2 2 2 0 Geminivirus coat protein/nuclear export factor BR1 family Pex14_N PF04695.13 CDJ64269.1 - 0.024 15.3 14.4 0.024 15.3 14.4 3.6 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3995 PF13160.6 CDJ64269.1 - 2.5 8.5 15.2 0.29 11.5 7.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) SR-25 PF10500.9 CDJ64269.1 - 4.4 6.8 59.9 0.045 13.4 18.8 3.1 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S30 PF01577.16 CDJ64269.1 - 6.5 6.3 14.7 3.2 7.3 6.4 2.1 2 0 0 2 2 2 0 Potyvirus P1 protease RskA PF10099.9 CDJ64270.1 - 0.0035 17.7 0.0 0.007 16.7 0.0 1.5 1 1 0 1 1 1 1 Anti-sigma-K factor rskA SbcCD_C PF13558.6 CDJ64270.1 - 0.0039 17.4 0.2 0.0039 17.4 0.2 1.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF4834 PF16118.5 CDJ64270.1 - 0.031 15.3 0.2 0.031 15.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TetR_C_1 PF02909.17 CDJ64270.1 - 0.036 13.9 0.3 0.036 13.9 0.3 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RNA_pol_Rbc25 PF08292.12 CDJ64270.1 - 0.22 11.8 5.4 1.9 8.7 0.2 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 SUIM_assoc PF16619.5 CDJ64270.1 - 0.26 11.4 24.2 13 6.0 24.2 2.7 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 7TMR-HDED PF07697.11 CDJ64270.1 - 0.32 11.1 12.0 0.84 9.7 12.0 1.6 1 1 0 1 1 1 0 7TM-HD extracellular BRF1 PF07741.13 CDJ64270.1 - 0.53 10.7 11.7 0.77 10.1 3.3 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain G0-G1_switch_2 PF15103.6 CDJ64270.1 - 5.1 7.6 9.0 2.2 8.7 0.4 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 FliD_N PF02465.18 CDJ64271.1 - 0.0017 19.0 5.6 0.0025 18.5 5.6 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus DUF755 PF05501.11 CDJ64271.1 - 0.015 15.6 17.4 0.021 15.1 17.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Syja_N PF02383.18 CDJ64271.1 - 0.019 14.3 2.5 0.022 14.1 2.5 1.0 1 0 0 1 1 1 0 SacI homology domain Spt20 PF12090.8 CDJ64271.1 - 0.027 14.1 8.1 0.035 13.7 8.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF1635 PF07795.11 CDJ64271.1 - 0.05 13.5 3.9 0.084 12.7 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) PAP1 PF08601.10 CDJ64271.1 - 0.072 12.8 4.7 0.087 12.5 4.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 GREB1 PF15782.5 CDJ64271.1 - 0.16 9.1 4.2 0.18 8.9 4.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ64271.1 - 0.19 11.3 4.8 0.24 10.9 4.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist IPK PF03770.16 CDJ64271.1 - 0.22 11.4 3.2 0.27 11.0 3.2 1.1 1 0 0 1 1 1 0 Inositol polyphosphate kinase Herpes_pp85 PF04637.12 CDJ64271.1 - 0.26 9.7 1.6 0.28 9.5 1.6 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) AF-4 PF05110.13 CDJ64271.1 - 0.44 8.6 11.2 0.55 8.3 11.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4175 PF13779.6 CDJ64271.1 - 0.51 8.2 9.6 0.65 7.8 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.13 CDJ64271.1 - 0.61 10.0 11.0 0.76 9.7 11.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rrn6 PF10214.9 CDJ64271.1 - 1.5 7.2 15.1 1.9 6.9 15.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor WD40 PF00400.32 CDJ64272.1 - 3.1e-14 53.1 16.9 0.00012 22.8 0.1 7.5 7 1 0 7 7 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ64272.1 - 2.3e-05 24.6 0.0 0.45 10.8 0.0 4.8 7 0 0 7 7 6 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2722 PF10846.8 CDJ64272.1 - 0.0048 15.9 0.4 0.0048 15.9 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ64272.1 - 0.035 13.7 17.7 0.057 13.0 6.3 2.3 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 CDJ64272.1 - 0.054 13.6 0.6 0.054 13.6 0.6 3.5 3 1 0 3 3 2 0 Unstructured region C-term to UIM in Ataxin3 Ge1_WD40 PF16529.5 CDJ64272.1 - 0.07 12.1 0.1 0.16 10.9 0.1 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ64272.1 - 0.092 11.4 2.7 2.8 6.5 0.3 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 TFIIA PF03153.13 CDJ64272.1 - 0.17 11.9 22.2 0.023 14.7 17.9 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ64272.1 - 0.22 10.5 3.0 0.47 9.4 3.0 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RAB3GAP2_N PF14655.6 CDJ64272.1 - 0.41 9.8 11.1 3.9 6.6 0.7 4.6 5 1 0 5 5 5 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.10 CDJ64272.1 - 0.46 9.1 21.7 1.2 7.8 21.7 1.7 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal THOC2_N PF16134.5 CDJ64272.1 - 4.4 5.8 6.7 6.5 5.3 6.7 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus ANAPC_CDC26 PF10471.9 CDJ64272.1 - 5 8.0 23.0 6.9 7.6 4.9 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Suf PF05843.14 CDJ64272.1 - 7.4 6.5 7.8 12 5.7 7.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1645 PF07816.11 CDJ64273.1 - 0.0022 18.6 24.6 0.024 15.2 2.7 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1645) MITF_TFEB_C_3_N PF15951.5 CDJ64273.1 - 0.027 15.1 1.6 0.027 15.1 1.6 6.8 6 2 1 7 7 7 0 MITF/TFEB/TFEC/TFE3 N-terminus Ribonuc_P_40 PF08584.11 CDJ64273.1 - 3.9 6.7 12.8 0.3 10.3 7.1 2.0 2 0 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit SPX PF03105.19 CDJ64273.1 - 7.4 6.4 26.2 1.5 8.7 1.1 2.9 2 1 1 3 3 3 0 SPX domain RCC1_2 PF13540.6 CDJ64274.1 - 1.9e-11 43.4 9.1 7.1e-05 22.5 0.1 5.4 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CDJ64274.1 - 3.8e-07 30.6 7.3 0.77 10.4 0.0 6.2 7 0 0 7 7 6 2 Regulator of chromosome condensation (RCC1) repeat DUF2722 PF10846.8 CDJ64274.1 - 2.2e-05 23.6 1.7 2.2e-05 23.6 1.7 3.1 2 1 1 3 3 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ64274.1 - 3.5e-05 24.0 34.2 0.0031 17.6 6.4 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ64274.1 - 0.0047 16.6 13.5 0.0047 16.6 13.5 2.9 2 1 0 2 2 1 1 Spt20 family Med15 PF09606.10 CDJ64274.1 - 0.0051 15.6 38.5 0.0055 15.5 8.8 2.3 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Es2 PF09751.9 CDJ64274.1 - 0.013 15.3 4.7 0.019 14.8 0.4 2.0 2 0 0 2 2 2 0 Nuclear protein Es2 BRF1 PF07741.13 CDJ64274.1 - 0.066 13.6 8.2 2.9 8.3 0.3 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain SARAF PF06682.12 CDJ64274.1 - 0.13 11.9 10.5 1.6 8.3 5.6 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis V_ATPase_I PF01496.19 CDJ64274.1 - 0.22 9.4 11.5 2.2 6.1 8.4 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family EPL1 PF10513.9 CDJ64274.1 - 0.22 11.9 11.7 3.3 8.1 5.1 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Neur_chan_memb PF02932.16 CDJ64274.1 - 0.23 11.5 8.0 3.4 7.7 4.6 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region OATP PF03137.20 CDJ64274.1 - 0.29 9.3 5.1 0.37 9.0 0.8 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family U3_snoRNA_assoc PF08297.11 CDJ64274.1 - 0.35 11.6 7.5 3.8 8.3 0.2 2.4 2 0 0 2 2 2 0 U3 snoRNA associated Peptidase_S49_N PF08496.10 CDJ64274.1 - 0.41 10.7 10.5 2.4 8.2 4.3 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal BORG_CEP PF14957.6 CDJ64274.1 - 0.65 11.2 4.1 4.9 8.3 1.1 2.3 2 0 0 2 2 2 0 Cdc42 effector PAT1 PF09770.9 CDJ64274.1 - 0.65 8.2 23.8 0.26 9.5 1.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Hydin_ADK PF17213.3 CDJ64274.1 - 0.73 10.1 13.9 0.67 10.2 3.9 2.9 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain RskA PF10099.9 CDJ64274.1 - 0.87 9.9 28.7 3.2e+02 1.5 19.2 3.6 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Fer4_22 PF17179.4 CDJ64274.1 - 1 10.3 10.2 0.31 11.9 5.3 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain PRC2_HTH_1 PF18118.1 CDJ64274.1 - 1.2 10.0 6.6 13 6.6 2.2 2.3 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain AUX_IAA PF02309.16 CDJ64274.1 - 1.3 8.8 6.8 24 4.7 5.4 2.1 2 0 0 2 2 2 0 AUX/IAA family Tim54 PF11711.8 CDJ64274.1 - 1.4 7.6 7.9 3.3 6.4 2.8 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CCDC53 PF10152.9 CDJ64274.1 - 2.3 8.6 14.7 8.6 6.8 1.2 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Folliculin PF11704.8 CDJ64274.1 - 2.4 8.0 9.3 4.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Connexin PF00029.19 CDJ64274.1 - 2.6 7.7 8.2 17 5.1 4.7 2.1 2 0 0 2 2 2 0 Connexin PIP5K PF01504.18 CDJ64274.1 - 2.9 7.1 10.5 8.9 5.4 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF2828 PF11443.8 CDJ64274.1 - 5.1 5.1 12.3 12 3.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF4569 PF15133.6 CDJ64274.1 - 5.8 6.5 18.1 1.2 8.8 7.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) ALMT PF11744.8 CDJ64274.1 - 6 5.6 7.5 8 5.2 3.7 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter PNISR PF15996.5 CDJ64274.1 - 7.1 6.8 18.2 2 8.6 5.9 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DUF1764 PF08576.10 CDJ64274.1 - 9.4 7.2 12.5 20 6.2 0.3 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) eIF-3_zeta PF05091.12 CDJ64274.1 - 10 5.0 22.0 4.2 6.2 3.4 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rhomboid PF01694.22 CDJ64276.1 - 2e-16 60.3 8.2 5.7e-16 58.9 8.2 1.8 1 0 0 1 1 1 1 Rhomboid family Macoilin PF09726.9 CDJ64276.1 - 0.00031 19.4 9.1 0.00031 19.4 9.1 3.2 3 0 0 3 3 3 1 Macoilin family Nha1_C PF08619.10 CDJ64276.1 - 0.2 10.8 36.9 0.074 12.3 18.9 2.6 3 0 0 3 3 3 0 Alkali metal cation/H+ antiporter Nha1 C terminus Pkinase PF00069.25 CDJ64276.1 - 0.43 9.9 5.5 0.71 9.2 0.0 2.9 2 1 0 2 2 2 0 Protein kinase domain SAPS PF04499.15 CDJ64276.1 - 8.3 5.1 25.2 4.7 5.9 15.7 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SPX PF03105.19 CDJ64276.1 - 9.8 6.0 21.8 2.4 8.0 8.5 3.3 3 0 0 3 3 3 0 SPX domain SID-1_RNA_chan PF13965.6 CDJ64277.1 - 1.6 7.1 4.6 14 4.0 2.4 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 RskA PF10099.9 CDJ64278.1 - 0.015 15.6 3.1 0.015 15.6 3.1 3.6 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Pex14_N PF04695.13 CDJ64278.1 - 0.02 15.6 23.9 0.02 15.6 23.9 5.1 1 1 4 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region VKG_Carbox PF05090.14 CDJ64278.1 - 4.7 5.9 5.3 9.9 4.9 5.3 1.5 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase TFIIA PF03153.13 CDJ64279.1 - 9.9e-05 22.5 12.3 0.00011 22.4 12.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ64279.1 - 0.0012 18.5 15.9 0.0014 18.3 15.9 1.1 1 0 0 1 1 1 1 Spt20 family EPL1 PF10513.9 CDJ64279.1 - 0.034 14.5 2.0 0.033 14.6 2.0 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF908 PF06012.12 CDJ64279.1 - 0.038 13.4 4.2 0.047 13.1 4.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TPX2 PF06886.11 CDJ64279.1 - 0.057 13.7 11.6 0.099 12.9 11.6 1.4 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Med15 PF09606.10 CDJ64279.1 - 0.063 12.0 18.4 0.078 11.7 18.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4770 PF15994.5 CDJ64279.1 - 0.083 13.1 3.9 0.1 12.8 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4400 PF14348.6 CDJ64279.1 - 0.1 12.1 5.1 0.14 11.7 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) DUF4638 PF15472.6 CDJ64279.1 - 0.18 11.5 2.8 0.19 11.4 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) PAT1 PF09770.9 CDJ64279.1 - 0.2 9.9 10.8 0.22 9.7 10.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 CDJ64279.1 - 0.26 9.9 8.2 0.28 9.8 8.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NST1 PF13945.6 CDJ64279.1 - 0.71 10.0 11.4 0.99 9.5 11.4 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator GREB1 PF15782.5 CDJ64279.1 - 0.75 6.8 6.1 0.81 6.7 6.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 CDJ64279.1 - 0.97 9.4 3.3 1.2 9.1 3.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DLIC PF05783.11 CDJ64279.1 - 2.1 7.1 7.5 2.4 6.9 7.5 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) XRN_M PF17846.1 CDJ64279.1 - 3 6.7 5.2 3.9 6.3 5.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain CPSF100_C PF13299.6 CDJ64279.1 - 3.4 7.8 8.0 5.2 7.2 8.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CDJ64279.1 - 4.7 5.9 9.5 5.8 5.6 9.5 1.1 1 0 0 1 1 1 0 Presenilin BAT2_N PF07001.11 CDJ64279.1 - 7.5 7.0 19.6 0.53 10.7 14.5 1.6 2 0 0 2 2 2 0 BAT2 N-terminus TERB2 PF15101.6 CDJ64279.1 - 8.3 6.4 10.8 12 5.9 10.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MecA PF05389.12 CDJ64279.1 - 8.3 6.0 8.1 38 3.8 8.1 1.8 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) ERO1 PF04137.15 CDJ64280.1 - 3.6e-32 111.9 7.2 2e-27 96.3 4.8 2.6 2 1 0 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) RskA PF10099.9 CDJ64280.1 - 0.0006 20.2 3.4 0.0006 20.2 3.4 5.9 1 1 1 3 3 3 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ64281.1 - 0.082 13.0 12.7 0.82 9.8 0.2 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ64281.1 - 0.58 9.7 4.1 6.1 6.4 1.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ64281.1 - 1.9 8.0 7.7 3.3 7.3 2.6 2.2 2 0 0 2 2 2 0 Spt20 family FAM199X PF15814.5 CDJ64281.1 - 6.1 5.8 11.4 8.8 5.3 9.4 1.9 2 0 0 2 2 2 0 Protein family FAM199X ArsA_ATPase PF02374.15 CDJ64282.1 - 1.1e-38 133.2 0.0 1.2e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CDJ64282.1 - 1.1e-10 41.8 0.0 1.2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CDJ64282.1 - 3.4e-10 40.1 0.0 3.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CDJ64282.1 - 2e-06 27.4 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 CDJ64282.1 - 2.4e-05 23.9 0.1 3.3e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 CDJ64282.1 - 0.00054 19.5 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 CDJ64282.1 - 0.0006 19.5 0.0 0.00066 19.4 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CDJ64282.1 - 0.0025 17.1 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.22 CDJ64282.1 - 0.0038 16.4 0.0 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.20 CDJ64282.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase VirC1 PF07015.11 CDJ64282.1 - 0.023 14.0 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 VirC1 protein AAA_16 PF13191.6 CDJ64282.1 - 0.027 14.8 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CDJ64282.1 - 0.029 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 CDJ64282.1 - 0.033 14.2 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PTPlike_phytase PF14566.6 CDJ64282.1 - 0.038 14.1 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate NACHT PF05729.12 CDJ64282.1 - 0.043 13.7 0.8 0.079 12.9 0.8 1.5 1 1 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 CDJ64282.1 - 0.06 13.1 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CDJ64282.1 - 0.062 13.9 0.0 0.075 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 CDJ64282.1 - 0.073 12.4 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase PF06745.13 CDJ64282.1 - 0.086 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 KaiC PIF1 PF05970.14 CDJ64282.1 - 0.1 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase ABC_tran PF00005.27 CDJ64282.1 - 0.11 13.1 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 ABC transporter MipZ PF09140.11 CDJ64282.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ LSDAT_prok PF18171.1 CDJ64282.1 - 0.15 11.3 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote PhoH PF02562.16 CDJ64282.1 - 0.15 11.4 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein MeaB PF03308.16 CDJ64282.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 CDJ64282.1 - 0.16 11.5 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L6e PF01159.19 CDJ64283.1 - 6.4e-33 113.6 1.9 8.8e-33 113.2 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e CCDC53 PF10152.9 CDJ64283.1 - 0.019 15.4 1.3 0.026 15.0 1.3 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Kelch_3 PF13415.6 CDJ64284.1 - 1.9e-20 72.7 0.1 4.9e-06 26.7 0.1 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 CDJ64284.1 - 3e-17 62.3 1.0 4.5e-05 23.4 0.1 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ64284.1 - 1.2e-12 47.5 0.3 0.015 15.3 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 CDJ64284.1 - 1.3e-08 34.8 0.0 2 8.9 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CDJ64284.1 - 2.5e-08 33.6 1.9 0.25 11.4 1.1 5.0 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CDJ64284.1 - 0.0026 17.3 0.1 4.8 6.8 0.1 4.1 4 0 0 4 4 4 1 Kelch motif Prefoldin PF02996.17 CDJ64284.1 - 6.1 6.8 10.2 2.9 7.8 1.0 2.7 2 0 0 2 2 2 0 Prefoldin subunit VWA_2 PF13519.6 CDJ64287.1 - 0.022 15.4 0.4 0.079 13.6 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain HNOBA PF07701.14 CDJ64287.1 - 0.12 11.8 0.2 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 Heme NO binding associated CRF PF00473.17 CDJ64287.1 - 0.94 9.6 5.2 3.1 8.0 5.2 1.8 1 0 0 1 1 1 0 Corticotropin-releasing factor family GTP_EFTU PF00009.27 CDJ64288.1 - 2.1e-54 184.0 0.4 9.1e-32 110.2 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CDJ64288.1 - 2.6e-29 101.5 0.0 2.6e-29 101.5 0.0 2.1 3 0 0 3 3 2 1 Elongation factor G, domain IV EFG_II PF14492.6 CDJ64288.1 - 3.5e-22 78.3 1.0 4.3e-22 78.0 0.1 1.6 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 CDJ64288.1 - 1.6e-18 66.5 0.0 1.1e-10 41.4 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDJ64288.1 - 6.5e-10 39.3 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CDJ64288.1 - 9.2e-06 25.5 1.3 2.3e-05 24.2 1.3 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SR-25 PF10500.9 CDJ64288.1 - 3e-05 23.7 3.0 3e-05 23.7 3.0 4.1 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ64288.1 - 0.008 15.8 8.3 0.008 15.8 8.3 2.3 2 0 0 2 2 2 1 Spt20 family CCSAP PF15748.5 CDJ64288.1 - 0.058 13.6 18.1 0.074 13.2 3.2 3.4 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated Septin PF00735.18 CDJ64288.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Septin Apt1 PF10351.9 CDJ64288.1 - 0.68 8.7 9.0 8.1 5.2 9.0 2.2 1 1 0 1 1 1 0 Golgi-body localisation protein domain DUF418 PF04235.12 CDJ64290.1 - 0.38 10.7 7.8 1.2 9.0 2.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF418) SEP PF08059.13 CDJ64291.1 - 8.8e-21 74.3 0.2 1.5e-20 73.5 0.2 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CDJ64291.1 - 2.4e-13 50.1 0.0 3.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 UBX domain Androgen_recep PF02166.16 CDJ64291.1 - 0.014 14.2 12.7 0.13 11.1 0.0 2.2 2 0 0 2 2 2 0 Androgen receptor Pribosyltran PF00156.27 CDJ64292.1 - 5.9e-19 68.1 0.0 7.3e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 CDJ64292.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Nucleoside_tran PF01733.18 CDJ64293.1 - 8.2e-17 61.5 6.5 8.2e-17 61.5 6.5 2.4 2 1 0 2 2 2 2 Nucleoside transporter NRN1 PF15056.6 CDJ64294.1 - 0.09 12.9 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Neuritin protein family Endostatin PF06482.11 CDJ64295.1 - 0.0087 15.6 8.4 0.0087 15.6 8.4 1.9 2 0 0 2 2 2 1 Collagenase NC10 and Endostatin FAM60A PF15396.6 CDJ64295.1 - 9.4 6.2 12.7 2.3 8.2 6.5 2.4 2 0 0 2 2 2 0 Protein Family FAM60A GAT PF03127.14 CDJ64297.1 - 0.13 12.6 0.1 0.33 11.3 0.0 1.6 2 0 0 2 2 2 0 GAT domain PARP PF00644.20 CDJ64298.1 - 1.9e-53 181.0 0.0 4e-53 179.9 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CDJ64298.1 - 6.7e-34 116.9 2.0 1.1e-33 116.2 1.3 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CDJ64298.1 - 9.1e-11 41.7 1.8 1.6e-10 40.9 0.9 1.9 2 0 0 2 2 2 1 WGR domain BRCT PF00533.26 CDJ64298.1 - 3.1e-07 30.7 0.0 9.6e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-PARP PF00645.18 CDJ64298.1 - 0.00021 22.1 0.1 0.00055 20.7 0.1 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Ribosomal_L27e PF01777.18 CDJ64299.1 - 1.3e-23 83.1 4.6 1.7e-23 82.8 4.6 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CDJ64299.1 - 0.00051 19.9 2.5 0.00093 19.1 2.5 1.4 1 0 0 1 1 1 1 KOW motif rRNA_proc-arch PF13234.6 CDJ64299.1 - 0.041 13.8 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 rRNA-processing arch domain Uds1 PF15456.6 CDJ64300.1 - 3.2 7.9 4.7 13 5.9 0.1 2.9 4 0 0 4 4 4 0 Up-regulated During Septation TssN PF17555.2 CDJ64302.1 - 0.83 9.0 5.4 1 8.7 5.4 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Prolamin_like PF05617.11 CDJ64303.1 - 0.042 14.0 0.1 0.61 10.3 0.0 2.0 2 0 0 2 2 2 0 Prolamin-like Glyoxalase PF00903.25 CDJ64305.1 - 4.9e-05 23.5 0.0 0.067 13.4 0.0 3.4 3 0 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3584 PF12128.8 CDJ64305.1 - 0.0012 16.5 18.4 0.0012 16.5 18.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Glyoxalase_4 PF13669.6 CDJ64305.1 - 0.042 14.1 1.6 1.2 9.4 0.2 3.4 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CENP-K PF11802.8 CDJ64305.1 - 1.6 8.2 22.1 3.1 7.3 22.1 1.4 1 0 0 1 1 1 0 Centromere-associated protein K DUF572 PF04502.13 CDJ64305.1 - 5.9 6.4 17.9 0.4 10.3 12.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) ALMT PF11744.8 CDJ64305.1 - 7 5.4 11.2 13 4.4 11.2 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter CorA PF01544.18 CDJ64305.1 - 8 5.7 11.2 13 5.0 11.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.19 CDJ64305.1 - 8.9 4.1 13.7 13 3.5 13.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IF3_C PF00707.22 CDJ64306.1 - 1.2e-16 60.4 0.0 4.8e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain DCP1 PF06058.13 CDJ64307.1 - 1.3e-16 60.5 0.0 1.8e-08 34.3 0.0 2.8 2 0 0 2 2 2 2 Dcp1-like decapping family GSH_synth_ATP PF03917.17 CDJ64308.1 - 2.7e-59 200.8 12.7 8e-37 126.9 8.6 3.5 3 1 0 3 3 3 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CDJ64308.1 - 3e-18 66.1 0.0 1.1e-17 64.4 0.0 2.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Spt20 PF12090.8 CDJ64308.1 - 4.3 6.9 77.8 0.2 11.2 6.8 7.0 7 0 0 7 7 7 0 Spt20 family zf-C3HC4_2 PF13923.6 CDJ64309.1 - 8.6e-08 31.9 13.1 1.5e-07 31.2 13.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ64309.1 - 7.8e-06 26.1 13.8 1.3e-05 25.4 13.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ64309.1 - 1.1e-05 25.1 12.8 1.8e-05 24.5 12.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ64309.1 - 1.3e-05 24.9 14.1 2.3e-05 24.2 14.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ64309.1 - 0.00099 19.0 12.5 0.0018 18.2 12.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ64309.1 - 0.0012 18.8 12.2 0.0042 17.1 12.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 CDJ64309.1 - 0.011 15.6 7.9 0.022 14.6 7.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RAWUL PF16207.5 CDJ64309.1 - 0.02 15.6 0.1 0.077 13.7 0.1 2.1 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-Nse PF11789.8 CDJ64309.1 - 0.11 12.4 8.3 0.24 11.2 8.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CDJ64309.1 - 0.34 11.1 12.4 0.82 9.9 12.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CDJ64309.1 - 0.48 10.7 7.3 1.6 9.1 7.3 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CDJ64309.1 - 0.79 9.8 4.2 2.5 8.2 4.2 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CDJ64309.1 - 1 9.2 10.3 1.9 8.4 10.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 CDJ64309.1 - 1.6 8.7 9.1 2.7 8.0 8.4 1.8 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ64309.1 - 2.5 8.0 13.1 25 4.8 13.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 CDJ64310.1 - 9.3e-72 241.6 0.4 1.3e-71 241.1 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ64310.1 - 4.5e-37 127.7 0.1 6.6e-37 127.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ64310.1 - 1e-27 93.5 9.1 1.1e-06 27.7 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CDJ64310.1 - 4.6e-24 82.8 8.1 3.6e-07 29.4 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDJ64310.1 - 4.8e-23 79.1 4.2 3.3e-05 23.5 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CDJ64310.1 - 2e-21 76.2 3.9 1e-09 38.7 0.6 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ64310.1 - 1.7e-10 40.6 7.6 0.0011 18.7 0.2 4.5 3 1 1 4 4 4 3 EF-hand domain pair Pkinase_fungal PF17667.1 CDJ64310.1 - 6.8e-07 28.4 0.0 1.1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ64310.1 - 6.6e-06 25.6 0.2 1.3e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.7 CDJ64310.1 - 7.6e-06 25.8 4.1 0.0073 16.2 0.1 3.6 1 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ64310.1 - 2.1e-05 24.8 0.6 0.4 11.0 0.5 3.2 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 CDJ64310.1 - 0.00072 18.9 0.2 0.003 16.9 0.2 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ64310.1 - 0.0055 16.7 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_10 PF14788.6 CDJ64310.1 - 0.046 13.6 0.2 0.59 10.0 0.0 2.7 2 0 0 2 2 2 0 EF hand WD40 PF00400.32 CDJ64312.1 - 3.1e-06 27.8 1.7 0.13 13.1 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ64312.1 - 4.9e-05 23.5 0.2 0.0048 17.2 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 CDJ64312.1 - 0.00048 20.2 41.9 0.083 12.9 5.8 5.1 5 0 0 5 5 5 4 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ64312.1 - 0.08 12.5 61.3 0.58 9.7 10.6 5.1 5 0 0 5 5 5 0 Spt20 family DUF2722 PF10846.8 CDJ64312.1 - 0.57 9.1 43.1 1 8.3 0.6 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2722) FAM199X PF15814.5 CDJ64313.1 - 0.0035 16.5 14.0 0.0035 16.5 14.0 2.0 1 1 1 2 2 2 1 Protein family FAM199X RED_N PF07808.13 CDJ64313.1 - 0.0046 16.6 3.3 0.0055 16.3 3.3 1.0 1 0 0 1 1 1 1 RED-like protein N-terminal region TFIIA PF03153.13 CDJ64313.1 - 0.015 15.4 19.9 0.017 15.1 19.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.11 CDJ64313.1 - 0.048 13.9 26.5 0.069 13.4 26.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RskA PF10099.9 CDJ64313.1 - 0.078 13.3 25.2 0.11 12.8 25.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF677 PF05055.12 CDJ64313.1 - 0.12 11.3 3.2 0.14 11.0 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) NEMP PF10225.9 CDJ64313.1 - 0.21 11.2 6.3 0.26 10.9 6.3 1.1 1 0 0 1 1 1 0 NEMP family SR-25 PF10500.9 CDJ64313.1 - 0.24 11.0 31.4 0.52 9.9 3.1 1.9 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein eIF-3_zeta PF05091.12 CDJ64313.1 - 0.29 10.1 8.6 0.31 10.0 8.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.15 CDJ64313.1 - 0.5 9.9 8.4 0.56 9.7 8.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MMR1 PF08505.10 CDJ64313.1 - 0.58 10.4 11.9 0.66 10.2 11.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Ctr PF04145.15 CDJ64313.1 - 0.79 10.3 3.9 1 10.0 3.9 1.3 1 0 0 1 1 1 0 Ctr copper transporter family DUF4692 PF15763.5 CDJ64313.1 - 0.83 10.1 10.1 1.4 9.3 10.1 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF3450 PF11932.8 CDJ64313.1 - 1 8.6 23.4 1.3 8.2 23.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spt20 PF12090.8 CDJ64313.1 - 1.1 8.8 15.7 1.3 8.6 15.7 1.1 1 0 0 1 1 1 0 Spt20 family Miga PF10265.9 CDJ64313.1 - 1.3 7.9 12.6 1.6 7.6 12.6 1.1 1 0 0 1 1 1 0 Mitoguardin DUF4834 PF16118.5 CDJ64313.1 - 2 9.4 5.9 2.5 9.1 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Peptidase_S15 PF02129.18 CDJ64313.1 - 2.1 7.9 11.6 2.5 7.6 11.6 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Exonuc_VII_L PF02601.15 CDJ64313.1 - 2.6 7.6 13.6 2.9 7.4 13.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit GREB1 PF15782.5 CDJ64313.1 - 3.7 4.6 17.9 4.4 4.3 17.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAP1 PF08601.10 CDJ64313.1 - 5.5 6.6 19.5 6.6 6.3 19.5 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 RRM_1 PF00076.22 CDJ64314.1 - 1.8e-06 27.7 0.0 0.00043 20.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 CDJ64314.1 - 3.8e-06 26.9 0.0 8.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 SPOC domain Spem1 PF15670.5 CDJ64314.1 - 0.01 15.4 0.2 0.01 15.4 0.2 4.4 4 1 1 5 5 5 0 Spermatid maturation protein 1 adh_short PF00106.25 CDJ64316.1 - 1.9e-11 43.8 12.3 6.8e-11 42.0 0.8 3.3 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ64316.1 - 2.2e-06 27.4 4.8 2.2e-06 27.4 4.8 3.3 4 0 0 4 4 4 2 Enoyl-(Acyl carrier protein) reductase Saf_2TM PF18303.1 CDJ64316.1 - 0.086 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF2207 PF09972.9 CDJ64316.1 - 0.39 9.4 0.4 13 4.4 0.0 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) FUN14 PF04930.15 CDJ64316.1 - 0.6 10.6 3.4 29 5.1 0.6 3.2 2 1 0 2 2 2 0 FUN14 family DUF5338 PF17273.2 CDJ64317.1 - 0.27 11.3 0.0 0.27 11.3 0.0 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5338) MTHFR_C PF12225.8 CDJ64317.1 - 1.4 8.7 5.7 7.1 6.4 0.1 3.1 3 0 0 3 3 3 0 Methylene-tetrahydrofolate reductase C terminal RskA PF10099.9 CDJ64320.1 - 0.00019 21.8 2.4 0.00019 21.8 2.4 6.4 2 2 2 4 4 4 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ64320.1 - 0.082 12.5 13.2 0.15 11.7 13.2 1.3 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ64320.1 - 0.23 10.3 7.7 0.36 9.7 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ64320.1 - 3.6 7.5 25.9 0.013 15.6 7.4 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CDJ64321.1 - 1e-63 215.2 0.0 2.8e-63 213.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ64321.1 - 3.3e-29 102.0 0.0 1.7e-28 99.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ64321.1 - 0.063 12.6 0.0 2.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Apt1 PF10351.9 CDJ64321.1 - 0.8 8.5 11.7 1.2 7.9 11.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAD_binding_1 PF00175.21 CDJ64322.1 - 6.6e-15 55.7 0.0 1e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CDJ64322.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain UPF0181 PF03701.14 CDJ64323.1 - 0.0064 16.1 3.2 0.032 13.9 0.5 2.8 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0181) DUF3742 PF12553.8 CDJ64323.1 - 0.19 11.9 1.8 0.47 10.6 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) TcdA_TcdB PF12919.7 CDJ64324.1 - 0.052 12.8 0.2 0.065 12.5 0.2 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Chromo PF00385.24 CDJ64325.1 - 2.7e-14 52.8 0.0 5.8e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 CDJ64327.1 - 3.7e-06 26.7 0.9 3.7e-06 26.7 0.9 2.3 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 CDJ64328.1 - 0.0094 16.2 0.0 0.023 14.9 0.0 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein START PF01852.19 CDJ64331.1 - 2.2e-22 79.5 0.2 3.3e-22 78.9 0.2 1.2 1 0 0 1 1 1 1 START domain LapA_dom PF06305.11 CDJ64331.1 - 0.13 12.1 0.1 0.4 10.5 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain ORC6 PF05460.13 CDJ64331.1 - 0.26 10.5 5.8 0.46 9.7 5.8 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) COX4 PF02936.14 CDJ64334.1 - 0.028 14.5 2.8 1.3 9.0 0.2 3.0 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV DUF5345 PF17280.2 CDJ64334.1 - 0.049 13.6 1.5 0.049 13.6 1.5 3.9 3 1 0 3 3 3 0 Family of unknown function (DUF5345) SR-25 PF10500.9 CDJ64334.1 - 0.088 12.4 19.9 0.51 9.9 0.1 3.0 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein DUF4834 PF16118.5 CDJ64334.1 - 0.14 13.1 22.6 1.9 9.5 2.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) CD20 PF04103.15 CDJ64334.1 - 0.2 11.7 5.6 0.17 12.0 1.0 2.7 2 1 1 3 3 3 0 CD20-like family SprA-related PF12118.8 CDJ64334.1 - 0.9 8.6 54.9 0.2 10.8 13.1 3.1 3 0 0 3 3 3 0 SprA-related family DUF4207 PF13904.6 CDJ64334.1 - 4.5 6.9 32.2 2.2 7.9 2.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) dsDNA_bind PF01984.20 CDJ64334.1 - 6.3 7.1 40.4 2.6 8.4 7.9 3.6 3 0 0 3 3 3 0 Double-stranded DNA-binding domain SRP-alpha_N PF04086.13 CDJ64334.1 - 7.7 6.3 24.0 8 6.3 2.0 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal RRM_1 PF00076.22 CDJ64337.1 - 1.1e-15 57.1 0.2 2.9e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ64337.1 - 0.0004 20.0 0.0 0.00046 19.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TauE PF01925.19 CDJ64339.1 - 3.6e-15 56.2 44.0 4.6e-07 29.7 11.2 3.2 2 1 1 3 3 3 3 Sulfite exporter TauE/SafE CBP_BcsG PF11658.8 CDJ64339.1 - 0.044 12.2 6.3 0.1 11.0 2.2 2.9 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsG DUF3487 PF11990.8 CDJ64339.1 - 0.072 13.0 0.0 0.072 13.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) TFIIA PF03153.13 CDJ64339.1 - 0.31 11.0 25.1 0.35 10.8 22.4 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit tRNA_anti-like PF12869.7 CDJ64339.1 - 0.61 9.7 13.2 2.5 7.7 1.9 3.4 3 0 0 3 3 3 0 tRNA_anti-like DUF4834 PF16118.5 CDJ64339.1 - 0.75 10.8 0.1 0.75 10.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) LST1 PF05083.13 CDJ64339.1 - 1 9.7 3.5 0.6 10.4 0.6 2.2 2 0 0 2 2 1 0 LST-1 protein PRA1 PF03208.19 CDJ64339.1 - 1 9.0 0.0 1 9.0 0.0 3.2 3 1 0 3 3 3 0 PRA1 family protein Miff PF05644.11 CDJ64339.1 - 1.2 8.7 11.8 0.46 10.1 9.2 1.5 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff EMP24_GP25L PF01105.24 CDJ64339.1 - 1.2 9.0 5.6 10 6.0 0.0 2.8 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD WBP-1 PF11669.8 CDJ64339.1 - 1.2 9.7 8.6 3.6 8.3 0.6 4.0 3 1 1 4 4 4 0 WW domain-binding protein 1 Neur_chan_memb PF02932.16 CDJ64339.1 - 1.4 8.9 4.1 0.35 10.9 0.6 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF5313 PF17240.2 CDJ64339.1 - 3.7 8.0 5.7 2.4 8.6 0.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5313) LZ_Tnp_IS66 PF13007.7 CDJ64341.1 - 0.61 10.9 6.7 4.8 8.0 0.6 2.6 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain SR-25 PF10500.9 CDJ64341.1 - 4.7 6.8 31.1 0.34 10.5 10.5 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GTP_EFTU PF00009.27 CDJ64342.1 - 4.1e-10 39.5 0.0 5.4e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PAM2 PF07145.15 CDJ64342.1 - 0.0076 15.9 0.1 0.023 14.4 0.1 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region GTP_EFTU PF00009.27 CDJ64343.1 - 4.1e-24 85.2 0.0 5.5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDJ64343.1 - 6.1e-08 33.0 0.0 1.5e-07 31.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ64343.1 - 0.00019 21.8 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 TFIIA PF03153.13 CDJ64344.1 - 0.018 15.1 19.5 0.02 14.9 19.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5569 PF17729.1 CDJ64344.1 - 0.066 13.1 6.8 0.12 12.3 6.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5569) DUF572 PF04502.13 CDJ64344.1 - 0.23 11.0 9.1 0.28 10.7 9.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAT1 PF09770.9 CDJ64344.1 - 1.4 7.1 18.6 1.6 6.9 18.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Erythro-docking PF09277.11 CDJ64344.1 - 7.5 6.5 7.2 15 5.6 0.4 3.0 3 0 0 3 3 3 0 Erythronolide synthase, docking Surface_antigen PF11054.8 CDJ64347.1 - 1.8e-74 250.5 4.5 2.2e-74 250.2 4.5 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ64348.1 - 3.4e-69 233.2 2.0 4e-69 233.0 2.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ64349.1 - 3e-57 194.1 5.9 3.4e-57 193.9 5.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ64350.1 - 7.7e-68 228.8 5.1 9e-68 228.6 5.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF4679 PF15728.5 CDJ64350.1 - 0.048 12.7 0.9 0.079 12.0 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) Surface_antigen PF11054.8 CDJ64351.1 - 1.3e-79 267.3 1.8 1.6e-79 267.0 1.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen GCD14 PF08704.10 CDJ64352.1 - 5.1e-63 213.0 0.0 3.1e-39 135.1 0.0 2.3 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CDJ64352.1 - 9.4e-06 25.5 0.0 9.7e-05 22.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 CDJ64352.1 - 0.0073 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CDJ64352.1 - 0.15 12.7 0.0 0.36 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain YqfQ PF14181.6 CDJ64353.1 - 0.0033 17.7 0.0 6.2 7.0 0.6 3.6 3 1 0 3 3 3 2 YqfQ-like protein Cwf_Cwc_15 PF04889.12 CDJ64353.1 - 0.25 11.1 7.6 0.018 14.8 2.0 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SUIM_assoc PF16619.5 CDJ64353.1 - 9.4 6.4 23.0 3.3 7.8 8.3 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ64356.1 - 1.7e-09 38.2 14.8 0.00022 21.5 0.0 3.2 1 1 2 3 3 3 2 Anti-sigma-K factor rskA NUC153 PF08159.12 CDJ64356.1 - 7.7e-07 28.8 0.1 1.4e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 NUC153 domain K_channel_TID PF07941.11 CDJ64356.1 - 0.027 14.9 8.7 0.027 14.9 8.7 5.2 5 1 0 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain OmpH PF03938.14 CDJ64356.1 - 2.8 8.3 39.9 0.57 10.5 15.6 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) HSP20 PF00011.21 CDJ64357.1 - 2.7e-17 62.8 0.3 9.7e-17 61.0 0.1 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ64357.1 - 2.5e-08 33.3 0.0 4.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Spore_YhcN_YlaJ PF09580.10 CDJ64357.1 - 3.6 7.6 11.4 0.29 11.2 2.1 2.7 2 1 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) PNISR PF15996.5 CDJ64359.1 - 0.07 13.4 51.0 0.091 13.0 51.0 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Caldesmon PF02029.15 CDJ64359.1 - 0.1 11.3 46.9 0.13 11.1 46.9 1.1 1 0 0 1 1 1 0 Caldesmon BAF1_ABF1 PF04684.13 CDJ64359.1 - 0.14 11.2 33.4 0.17 10.9 33.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ADH_zinc_N PF00107.26 CDJ64359.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ndc1_Nup PF09531.10 CDJ64359.1 - 0.25 10.0 37.1 0.29 9.8 37.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.14 CDJ64359.1 - 0.25 9.6 37.1 0.44 8.8 37.1 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF572 PF04502.13 CDJ64359.1 - 0.25 10.9 34.4 0.39 10.3 34.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dapper PF15268.6 CDJ64359.1 - 0.51 9.1 46.5 0.6 8.9 46.5 1.0 1 0 0 1 1 1 0 Dapper CCSAP PF15748.5 CDJ64359.1 - 1.5 8.9 49.4 2.4 8.3 49.4 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated AbLIM_anchor PF16182.5 CDJ64359.1 - 1.5 8.5 24.9 2.1 8.1 24.9 1.3 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM SAPS PF04499.15 CDJ64359.1 - 2.6 6.7 32.3 3.6 6.2 32.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4045 PF13254.6 CDJ64359.1 - 3.8 7.1 37.2 5.5 6.5 37.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF966 PF06136.13 CDJ64359.1 - 6.7 6.3 33.6 8.8 5.9 33.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RT_RNaseH PF17917.1 CDJ64360.1 - 6e-29 100.4 0.0 1e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ64360.1 - 1.4e-28 98.9 0.0 2.3e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ64360.1 - 1.2e-21 77.2 0.0 2.2e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 CDJ64360.1 - 0.00037 20.3 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like FAM92 PF06730.11 CDJ64360.1 - 0.034 13.6 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 FAM92 protein RNase_H PF00075.24 CDJ64360.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 RNase H rve PF00665.26 CDJ64361.1 - 2.5e-13 50.3 0.0 3.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ64361.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Acetyltransf_1 PF00583.25 CDJ64363.1 - 6.9e-11 42.4 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ64363.1 - 6.8e-08 32.8 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ64363.1 - 4.2e-06 26.7 0.0 7.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4603 PF15376.6 CDJ64363.1 - 2.1 5.7 10.0 2.7 5.2 10.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Presenilin PF01080.17 CDJ64363.1 - 2.1 7.0 5.4 3.5 6.3 5.4 1.3 1 1 0 1 1 1 0 Presenilin MA3 PF02847.17 CDJ64365.1 - 3.5e-08 33.4 1.2 8.5e-08 32.2 1.2 1.6 1 0 0 1 1 1 1 MA3 domain RskA PF10099.9 CDJ64365.1 - 3.6e-07 30.6 63.8 0.00011 22.6 0.0 6.4 3 2 2 5 5 5 4 Anti-sigma-K factor rskA RskA PF10099.9 CDJ64366.1 - 0.032 14.5 19.1 0.035 14.4 19.1 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA IHABP4_N PF16174.5 CDJ64366.1 - 0.1 13.2 12.5 0.11 13.1 12.5 1.0 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal SprA-related PF12118.8 CDJ64366.1 - 0.15 11.2 18.2 0.17 11.0 18.2 1.1 1 0 0 1 1 1 0 SprA-related family LPP20 PF02169.16 CDJ64366.1 - 0.15 12.4 10.0 0.16 12.3 10.0 1.0 1 0 0 1 1 1 0 LPP20 lipoprotein eIF_4EBP PF05456.11 CDJ64366.1 - 0.19 11.7 4.3 0.2 11.6 4.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Suf PF05843.14 CDJ64366.1 - 0.64 9.9 12.0 0.63 10.0 12.0 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Coilin_N PF15862.5 CDJ64366.1 - 0.65 9.8 7.9 0.7 9.7 7.9 1.0 1 0 0 1 1 1 0 Coilin N-terminus EIIBC-GUT_N PF03612.14 CDJ64366.1 - 0.83 9.4 6.5 0.87 9.3 6.5 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 CDJ64366.1 - 0.89 8.3 6.1 0.9 8.2 6.1 1.0 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ64366.1 - 0.89 9.5 23.8 0.91 9.4 23.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ64366.1 - 1.2 9.8 15.2 1.4 9.6 15.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5349 PF17298.2 CDJ64366.1 - 1.3 8.7 10.0 1.3 8.7 10.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF3464 PF11947.8 CDJ64366.1 - 1.4 8.6 6.0 1.6 8.5 6.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Activator_LAG-3 PF11498.8 CDJ64366.1 - 1.5 7.7 31.7 1.6 7.7 31.7 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ64366.1 - 1.7 8.2 26.4 1.8 8.1 26.4 1.0 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ64366.1 - 3.4 8.7 9.0 4 8.5 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4407 PF14362.6 CDJ64366.1 - 4.2 6.6 13.5 4.1 6.7 13.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ndc1_Nup PF09531.10 CDJ64366.1 - 4.5 5.9 9.0 4.3 5.9 9.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3138 PF11336.8 CDJ64366.1 - 4.6 5.7 10.6 5 5.6 10.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2561 PF10812.8 CDJ64366.1 - 5.4 7.0 6.8 5.7 6.9 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Kei1 PF08552.11 CDJ64366.1 - 7.3 6.4 7.8 8 6.3 7.8 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1645 PF07816.11 CDJ64367.1 - 3.1 8.3 45.7 0.19 12.3 15.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1645) Utp14 PF04615.13 CDJ64367.1 - 6.7 5.1 35.5 8.4 4.8 35.5 1.1 1 0 0 1 1 1 0 Utp14 protein TMEM247 PF15444.6 CDJ64369.1 - 0.19 11.7 5.1 0.22 11.6 5.1 1.0 1 0 0 1 1 1 0 Transmembrane protein 247 DciA PF05258.12 CDJ64369.1 - 0.23 11.9 3.1 0.27 11.7 3.1 1.1 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA DUF755 PF05501.11 CDJ64370.1 - 0.068 13.4 34.2 0.093 13.0 34.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) FAM91_C PF14648.6 CDJ64370.1 - 0.084 11.7 5.0 0.092 11.6 5.0 1.2 1 0 0 1 1 1 0 FAM91 C-terminus Band_3_cyto PF07565.13 CDJ64370.1 - 0.11 12.3 9.8 0.12 12.2 9.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MPM1 PF17234.2 CDJ64370.1 - 0.14 12.5 12.9 0.19 12.0 12.9 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Apt1 PF10351.9 CDJ64370.1 - 0.26 10.1 14.5 0.27 10.1 14.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain UPF0560 PF10577.9 CDJ64370.1 - 0.27 9.7 22.9 0.37 9.2 22.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Macoilin PF09726.9 CDJ64370.1 - 0.37 9.3 19.9 0.53 8.8 19.9 1.2 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 CDJ64370.1 - 0.51 9.1 11.8 0.53 9.0 11.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4638 PF15472.6 CDJ64370.1 - 0.65 9.7 7.9 0.68 9.6 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) GREB1 PF15782.5 CDJ64370.1 - 0.66 7.0 21.2 0.71 6.9 21.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Drf_GBD PF06371.13 CDJ64370.1 - 0.66 9.5 8.6 0.9 9.1 8.6 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain MMR1 PF08505.10 CDJ64370.1 - 0.77 10.0 22.8 0.97 9.7 22.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF5585 PF17823.1 CDJ64370.1 - 1.1 8.1 31.0 1.3 7.9 31.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Connexin PF00029.19 CDJ64370.1 - 1.2 8.9 7.7 1.5 8.5 7.7 1.2 1 0 0 1 1 1 0 Connexin Plasmodium_Vir PF05795.11 CDJ64370.1 - 1.5 8.2 9.8 1.6 8.1 9.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Draxin PF15550.6 CDJ64370.1 - 1.5 8.6 13.5 1.7 8.4 13.5 1.1 1 0 0 1 1 1 0 Draxin Miga PF10265.9 CDJ64370.1 - 1.9 7.4 18.4 2.2 7.2 18.4 1.0 1 0 0 1 1 1 0 Mitoguardin ALMT PF11744.8 CDJ64370.1 - 2.8 6.7 13.8 3 6.6 13.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TMEM51 PF15345.6 CDJ64370.1 - 2.8 7.7 20.0 3.5 7.4 20.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Paf1 PF03985.13 CDJ64370.1 - 2.8 6.8 17.3 4.1 6.3 17.3 1.2 1 0 0 1 1 1 0 Paf1 Membralin PF09746.9 CDJ64370.1 - 3.2 6.7 6.5 3.1 6.8 6.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein Spt20 PF12090.8 CDJ64370.1 - 3.2 7.3 46.5 0.064 12.9 39.9 1.4 2 0 0 2 2 2 0 Spt20 family NACHT_N PF17100.5 CDJ64370.1 - 4.1 7.2 15.9 5.1 6.9 15.9 1.2 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase SLC12 PF03522.15 CDJ64370.1 - 4.3 6.3 18.6 4.6 6.2 18.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ64370.1 - 4.4 7.3 15.1 5.2 7.1 15.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 CDJ64370.1 - 7.1 5.5 17.8 9.1 5.1 17.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Otopetrin PF03189.13 CDJ64370.1 - 7.2 5.3 8.4 8 5.1 8.4 1.2 1 0 0 1 1 1 0 Otopetrin ASFV_J13L PF05568.11 CDJ64370.1 - 8.4 6.1 26.1 11 5.7 26.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein SRP-alpha_N PF04086.13 CDJ64370.1 - 8.6 6.2 25.4 9.8 6.0 25.4 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Rrn6 PF10214.9 CDJ64370.1 - 8.6 4.7 24.9 9 4.6 24.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Spt20 PF12090.8 CDJ64371.1 - 0.014 15.1 5.1 0.014 15.1 5.1 2.1 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ64371.1 - 0.32 11.0 19.4 0.42 10.6 19.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 CDJ64371.1 - 1.7 7.2 7.8 1.8 7.1 7.8 1.0 1 0 0 1 1 1 0 Hamartin protein DUF2722 PF10846.8 CDJ64371.1 - 4.1 6.2 18.8 0.056 12.4 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4824 PF16106.5 CDJ64372.1 - 0.17 11.1 1.6 0.26 10.5 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) RAP1 PF07218.11 CDJ64372.1 - 3.9 5.6 5.1 5.2 5.2 5.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4813 PF16072.5 CDJ64372.1 - 9.3 5.8 21.3 14 5.2 21.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF4834 PF16118.5 CDJ64374.1 - 0.0054 17.7 9.9 1.7 9.7 0.7 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4834) ODV-E18 PF10717.9 CDJ64374.1 - 0.079 12.8 0.5 0.14 12.1 0.5 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 RcpC PF16976.5 CDJ64374.1 - 0.87 9.6 10.6 0.3 11.1 3.1 2.4 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB SRP9-21 PF05486.12 CDJ64374.1 - 1.5 9.3 6.0 7.1 7.1 0.6 2.8 3 0 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) RskA PF10099.9 CDJ64374.1 - 2.3 8.5 40.2 0.49 10.7 8.4 4.0 1 1 1 4 4 4 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ64374.1 - 3.4 6.3 9.9 0.083 11.6 2.9 1.8 2 0 0 2 2 2 0 Presenilin EphA2_TM PF14575.6 CDJ64374.1 - 4.3 8.3 8.5 1e+02 3.9 1.0 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Thioredoxin PF00085.20 CDJ64375.1 - 7.5e-12 45.1 0.3 2.1e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin SprA-related PF12118.8 CDJ64375.1 - 2.6e-06 26.8 14.6 3.1e-06 26.6 14.6 1.0 1 0 0 1 1 1 1 SprA-related family OST3_OST6 PF04756.13 CDJ64375.1 - 7.5e-06 25.5 0.0 7.5e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family SR-25 PF10500.9 CDJ64375.1 - 1.3e-05 24.9 18.0 1.6e-05 24.6 18.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 CDJ64375.1 - 0.00025 21.6 1.5 0.00025 21.6 1.5 1.2 1 0 0 1 1 1 1 AAA domain Thioredoxin_7 PF13899.6 CDJ64375.1 - 0.0008 19.5 0.1 0.0008 19.5 0.1 2.5 3 1 0 3 3 1 1 Thioredoxin-like FAM199X PF15814.5 CDJ64375.1 - 0.0011 18.1 13.2 0.0014 17.8 13.2 1.1 1 0 0 1 1 1 1 Protein family FAM199X RskA PF10099.9 CDJ64375.1 - 0.0062 16.9 2.4 0.0086 16.4 2.4 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ64375.1 - 0.023 14.7 17.5 0.03 14.3 17.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 CDJ64375.1 - 0.04 13.8 8.0 0.049 13.6 8.0 1.1 1 0 0 1 1 1 0 Velvet factor Thioredoxin_2 PF13098.6 CDJ64375.1 - 0.088 13.3 1.8 0.18 12.3 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain DUF4175 PF13779.6 CDJ64375.1 - 0.12 10.3 15.6 0.13 10.1 15.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) IMUP PF15761.5 CDJ64375.1 - 0.13 13.0 14.9 0.24 12.1 14.9 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein GvpL_GvpF PF06386.11 CDJ64375.1 - 0.14 12.1 5.6 0.23 11.4 5.6 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Connexin PF00029.19 CDJ64375.1 - 0.16 11.7 2.3 0.19 11.5 2.3 1.2 1 0 0 1 1 1 0 Connexin Thioredoxin_8 PF13905.6 CDJ64375.1 - 0.25 11.7 2.6 0.37 11.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like Neur_chan_memb PF02932.16 CDJ64375.1 - 0.28 11.2 4.2 0.34 10.9 4.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Folate_carrier PF01770.18 CDJ64375.1 - 0.28 9.9 6.6 0.33 9.7 6.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier TCP PF03634.13 CDJ64375.1 - 0.31 11.6 16.1 0.46 11.0 16.1 1.2 1 0 0 1 1 1 0 TCP family transcription factor RR_TM4-6 PF06459.12 CDJ64375.1 - 0.31 10.8 8.7 0.43 10.3 8.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 CDJ64375.1 - 0.4 10.6 13.2 0.54 10.2 13.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SMYLE_N PF18615.1 CDJ64375.1 - 0.42 10.1 10.0 0.56 9.7 10.0 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Presenilin PF01080.17 CDJ64375.1 - 0.53 9.0 14.2 0.64 8.7 14.2 1.1 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 CDJ64375.1 - 0.55 9.8 11.7 0.027 14.1 6.8 1.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) Thioredoxin_4 PF13462.6 CDJ64375.1 - 0.58 10.3 12.7 2.4 8.3 0.0 2.4 3 0 0 3 3 2 0 Thioredoxin LMBR1 PF04791.16 CDJ64375.1 - 0.65 8.8 2.4 0.69 8.8 2.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DDE_Tnp_1_2 PF13586.6 CDJ64375.1 - 0.72 10.3 4.4 14 6.1 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain DUF4407 PF14362.6 CDJ64375.1 - 1.3 8.3 10.7 1.9 7.8 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZYG-11_interact PF05884.12 CDJ64375.1 - 1.6 8.1 8.6 2 7.8 8.6 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 Zip PF02535.22 CDJ64375.1 - 2 7.5 5.0 2.5 7.3 5.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.10 CDJ64375.1 - 2.4 6.7 12.3 2.9 6.5 12.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4338 PF14236.6 CDJ64375.1 - 2.6 7.2 7.6 4.4 6.5 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) SOBP PF15279.6 CDJ64375.1 - 3.2 8.3 14.5 5.6 7.5 14.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Hydin_ADK PF17213.3 CDJ64375.1 - 8.6 6.6 16.8 11 6.3 16.8 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF5595 PF18077.1 CDJ64377.1 - 0.073 13.2 1.1 0.073 13.2 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) ERM PF00769.19 CDJ64377.1 - 0.61 9.9 24.3 0.42 10.4 19.2 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family TSC22 PF01166.18 CDJ64377.1 - 0.89 9.9 14.7 1.9 8.9 3.8 4.1 4 0 0 4 4 4 0 TSC-22/dip/bun family Rootletin PF15035.6 CDJ64377.1 - 2.5 8.1 19.1 0.11 12.5 10.6 2.5 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion GIT_CC PF16559.5 CDJ64377.1 - 2.5 8.0 20.2 0.075 12.9 6.5 4.1 4 1 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 CDJ64377.1 - 2.7 8.0 21.0 0.55 10.3 14.4 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 CDJ64377.1 - 3.5 8.3 17.2 0.28 11.8 8.0 3.1 2 1 1 3 3 3 0 Initiation control protein YabA DUF4201 PF13870.6 CDJ64377.1 - 5.6 6.7 22.6 8.3 6.1 15.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) V_ATPase_I PF01496.19 CDJ64377.1 - 5.9 4.7 7.1 7 4.4 7.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OST3_OST6 PF04756.13 CDJ64378.1 - 7e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Fcf1 PF04900.12 CDJ64379.1 - 1e-33 115.6 1.9 1e-33 115.6 1.9 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CDJ64379.1 - 2e-14 53.9 0.1 2e-14 53.9 0.1 1.5 2 0 0 2 2 2 1 PIN like domain PIN PF01850.21 CDJ64379.1 - 0.3 11.6 1.6 19 5.7 0.0 2.5 2 1 1 3 3 3 0 PIN domain YqzE PF14038.6 CDJ64379.1 - 3.6 7.7 7.2 7.1 6.7 7.2 1.6 1 0 0 1 1 1 0 YqzE-like protein SWI-SNF_Ssr4 PF08549.10 CDJ64380.1 - 0.016 13.8 2.1 0.018 13.7 2.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PP-binding PF00550.25 CDJ64381.1 - 0.0079 16.5 0.0 0.14 12.5 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site EF-hand_9 PF14658.6 CDJ64381.1 - 0.18 12.1 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain Ank_2 PF12796.7 CDJ64382.1 - 5.9e-39 132.5 0.2 2.9e-13 50.2 0.1 5.7 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ64382.1 - 5.7e-29 100.1 0.1 1.4e-05 25.6 0.0 7.9 5 2 4 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ64382.1 - 4.8e-28 96.9 3.7 0.00013 22.2 0.0 7.7 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ64382.1 - 3.3e-26 88.5 0.4 0.032 14.8 0.0 10.1 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 CDJ64382.1 - 9.1e-19 67.0 0.8 0.08 13.4 0.0 9.5 11 0 0 11 11 11 6 Ankyrin repeat Form_Nir_trans PF01226.17 CDJ64384.1 - 1.9e-05 24.2 2.6 2e-05 24.0 2.6 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter 5_nucleotid_C PF02872.18 CDJ64385.1 - 9e-37 126.7 0.0 1.9e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CDJ64385.1 - 3.3e-06 27.8 0.6 2.4e-05 25.0 0.6 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.7 CDJ64386.1 - 8.9e-05 22.3 0.7 8.9e-05 22.3 0.7 2.5 3 0 0 3 3 3 1 F-box-like FapA PF03961.13 CDJ64386.1 - 0.27 9.8 3.7 0.48 9.0 3.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A F-box PF00646.33 CDJ64386.1 - 0.27 11.2 3.0 1.3 9.0 3.0 2.3 1 0 0 1 1 1 0 F-box domain WXG100 PF06013.12 CDJ64386.1 - 0.64 10.3 10.7 0.54 10.5 1.7 3.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF569 PF04601.13 CDJ64387.1 - 0.049 13.3 0.1 0.09 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF569) MCU PF04678.13 CDJ64387.1 - 0.54 10.3 2.7 1.1 9.3 2.7 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter YitT_membrane PF02588.15 CDJ64387.1 - 4.1 6.7 7.2 2.2 7.6 1.7 2.4 2 0 0 2 2 2 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 CLAG PF03805.13 CDJ64390.1 - 6.5e-07 27.4 0.0 2.2e-06 25.6 0.0 1.7 1 1 0 2 2 2 1 Cytoadherence-linked asexual protein EGF_2 PF07974.13 CDJ64391.1 - 1.6e-20 73.2 189.2 0.00022 21.5 11.5 11.7 11 0 0 11 11 11 8 EGF-like domain AMA-1 PF02430.15 CDJ64391.1 - 3.4e-17 62.6 2.5 3e-13 49.6 0.7 2.9 3 0 0 3 3 3 2 Apical membrane antigen 1 hEGF PF12661.7 CDJ64391.1 - 1e-05 26.0 119.1 0.023 15.3 5.3 11.8 12 0 0 12 12 12 8 Human growth factor-like EGF EGF PF00008.27 CDJ64391.1 - 0.00068 19.9 26.6 0.0012 19.1 5.7 11.0 11 0 0 11 11 11 5 EGF-like domain TFIIA PF03153.13 CDJ64392.1 - 2.5 8.0 13.8 3 7.7 13.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S4 PF00163.19 CDJ64393.1 - 2.1e-06 28.5 0.3 3.5e-06 27.8 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain DUF2207 PF09972.9 CDJ64393.1 - 0.003 16.4 0.0 0.0037 16.1 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) FA_desaturase PF00487.24 CDJ64393.1 - 0.066 13.0 0.1 0.086 12.7 0.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase SUIM_assoc PF16619.5 CDJ64394.1 - 0.055 13.5 18.2 0.17 12.0 0.6 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ64394.1 - 0.42 10.6 12.6 0.56 10.1 12.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 CDJ64395.1 - 0.0032 17.5 17.3 0.0032 17.5 17.3 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ64396.1 - 0.31 11.3 22.5 0.43 10.8 22.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ64396.1 - 3.2 7.6 11.5 3.7 7.4 11.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tic110 PF16940.5 CDJ64396.1 - 3.7 5.9 13.9 3.5 6.0 13.9 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter FAM199X PF15814.5 CDJ64396.1 - 8.1 5.4 7.4 8.7 5.3 7.4 1.0 1 0 0 1 1 1 0 Protein family FAM199X UCH PF00443.29 CDJ64397.1 - 7e-31 107.6 0.0 9.1e-29 100.7 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ64397.1 - 7.5e-13 48.8 0.0 7.5e-13 48.8 0.0 4.2 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Spt20 PF12090.8 CDJ64397.1 - 0.00022 20.9 3.9 0.00022 20.9 3.9 7.1 6 1 0 6 6 6 5 Spt20 family O-antigen_lig PF13425.6 CDJ64397.1 - 0.3 9.8 4.8 0.79 8.4 4.8 1.6 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Proteasome PF00227.26 CDJ64398.1 - 1.9e-55 187.3 0.5 2.7e-55 186.8 0.5 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ64398.1 - 2.2e-12 46.4 0.0 4e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF4194 PF13835.6 CDJ64398.1 - 0.1 12.3 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) ORC5_C PF14630.6 CDJ64399.1 - 0.064 12.8 4.9 0.1 12.1 4.9 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Spt20 PF12090.8 CDJ64399.1 - 0.11 12.1 5.3 0.16 11.6 5.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF5523 PF17661.1 CDJ64400.1 - 0.072 12.8 24.5 0.12 12.0 24.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF4131 PF13567.6 CDJ64401.1 - 0.5 10.0 8.1 0.85 9.2 2.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) zf-rbx1 PF12678.7 CDJ64402.1 - 5.8e-06 26.5 1.2 5.8e-06 26.5 1.2 3.6 3 0 0 3 3 3 1 RING-H2 zinc finger domain Utp14 PF04615.13 CDJ64402.1 - 1.5e-05 23.9 0.2 1.5e-05 23.9 0.2 6.3 5 1 1 6 6 6 2 Utp14 protein zf-C3HC4 PF00097.25 CDJ64402.1 - 2.7e-05 24.0 11.6 0.00028 20.7 1.4 3.2 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ64402.1 - 0.00022 21.5 3.4 0.00022 21.5 3.4 3.9 4 0 0 4 4 4 1 Ring finger domain BAF1_ABF1 PF04684.13 CDJ64402.1 - 0.0016 17.6 6.0 0.0016 17.6 6.0 8.1 7 2 0 7 7 7 4 BAF1 / ABF1 chromatin reorganising factor zf-C3HC4_2 PF13923.6 CDJ64402.1 - 0.013 15.4 11.8 0.013 15.3 3.6 3.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 CDJ64402.1 - 4.2 7.7 15.8 0.2 12.0 6.6 3.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain Spt20 PF12090.8 CDJ64403.1 - 0.015 14.9 8.9 0.02 14.5 8.9 1.2 1 0 0 1 1 1 0 Spt20 family TMEM164 PF14808.6 CDJ64403.1 - 0.053 12.9 0.1 0.059 12.7 0.1 1.1 1 0 0 1 1 1 0 TMEM164 family Activator_LAG-3 PF11498.8 CDJ64403.1 - 0.068 12.1 11.1 0.08 11.9 11.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.10 CDJ64403.1 - 0.076 11.7 9.4 0.1 11.3 9.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Phostensin_N PF13916.6 CDJ64403.1 - 0.084 13.2 6.3 8.2 6.8 5.5 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal TFIIA PF03153.13 CDJ64403.1 - 0.22 11.5 7.2 0.26 11.3 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2116 PF09889.9 CDJ64403.1 - 1.6 8.7 5.1 3.6 7.6 5.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Yos1 PF08571.10 CDJ64403.1 - 3.3 8.1 5.0 13 6.2 5.0 1.8 1 1 0 1 1 1 0 Yos1-like p25-alpha PF05517.12 CDJ64405.1 - 1.2e-32 113.3 3.4 1.5e-32 112.9 3.4 1.1 1 0 0 1 1 1 1 p25-alpha EF-hand_7 PF13499.6 CDJ64405.1 - 0.0028 18.1 0.0 0.041 14.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair SurA_N PF09312.11 CDJ64405.1 - 0.0035 17.4 0.1 0.0059 16.7 0.1 1.3 1 0 0 1 1 1 1 SurA N-terminal domain EF-hand_6 PF13405.6 CDJ64405.1 - 0.088 12.8 0.9 2.1 8.5 0.0 3.0 3 1 0 3 3 3 0 EF-hand domain WD40 PF00400.32 CDJ64406.1 - 6.5e-21 74.3 0.3 0.0059 17.4 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ64406.1 - 3.5e-05 24.0 0.0 0.076 13.3 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RskA PF10099.9 CDJ64406.1 - 0.018 15.3 42.4 0.047 14.0 11.4 4.1 4 0 0 4 4 4 0 Anti-sigma-K factor rskA Ribosomal_S27e PF01667.17 CDJ64407.1 - 9.5e-14 50.9 0.6 1.3e-13 50.4 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 RNA_pol_N PF01194.17 CDJ64408.1 - 2.2e-32 111.1 0.5 2.6e-32 110.9 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Thioredoxin PF00085.20 CDJ64409.1 - 8.9e-13 48.1 0.1 1e-12 47.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDJ64409.1 - 0.0057 17.0 0.0 0.0079 16.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CDJ64409.1 - 0.15 12.0 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family SR-25 PF10500.9 CDJ64409.1 - 3.5 7.2 9.1 3.9 7.0 9.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CbiD PF01888.17 CDJ64410.1 - 0.018 14.3 11.7 0.038 13.3 1.9 2.2 2 0 0 2 2 2 0 CbiD Ribosomal_60s PF00428.19 CDJ64410.1 - 0.032 14.8 3.6 0.032 14.8 3.6 3.8 4 0 0 4 4 4 0 60s Acidic ribosomal protein DUF4179 PF13786.6 CDJ64410.1 - 0.075 13.5 7.2 3.2 8.3 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) RskA PF10099.9 CDJ64410.1 - 0.33 11.2 42.1 3.9 7.7 28.8 2.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA GT87 PF09594.10 CDJ64410.1 - 0.41 10.3 3.7 2.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 87 SRA1 PF07304.11 CDJ64411.1 - 0.0081 16.0 0.1 0.0081 16.0 0.1 2.1 1 1 1 2 2 2 1 Steroid receptor RNA activator (SRA1) Presenilin PF01080.17 CDJ64411.1 - 0.036 12.8 1.7 0.042 12.6 1.7 1.2 1 0 0 1 1 1 0 Presenilin Ni_hydr_CYTB PF01292.20 CDJ64411.1 - 0.062 12.9 0.1 0.076 12.6 0.1 1.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 CCDC53 PF10152.9 CDJ64411.1 - 0.079 13.4 13.7 1.3 9.5 0.1 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Pex14_N PF04695.13 CDJ64411.1 - 1.3 9.7 24.7 0.91 10.2 2.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 CDJ64411.1 - 6.7 6.7 8.7 4.3 7.4 5.1 1.9 2 0 0 2 2 2 0 Telomere-associated protein TERB2 SARAF PF06682.12 CDJ64411.1 - 7.3 6.1 11.1 26 4.3 7.3 1.9 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis PDEase_I PF00233.19 CDJ64413.1 - 5.4e-62 209.6 0.0 6.9e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CDJ64413.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 HD domain PDEase_I PF00233.19 CDJ64414.1 - 4.8e-47 160.7 0.2 8.5e-47 159.9 0.2 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Condensation PF00668.20 CDJ64416.1 - 0.4 9.3 9.1 1.4 7.5 0.1 3.3 4 0 0 4 4 4 0 Condensation domain HEAT PF02985.22 CDJ64417.1 - 0.08 13.2 0.1 1.3 9.5 0.1 3.2 1 0 0 1 1 1 0 HEAT repeat Diedel PF13164.6 CDJ64417.1 - 5.4 7.5 8.7 1.9 9.0 4.2 2.6 2 0 0 2 2 2 0 Diedel JmjC PF02373.22 CDJ64418.1 - 1.2e-34 119.2 0.6 1.2e-34 119.2 0.6 2.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 CDJ64418.1 - 0.0011 18.9 0.1 0.002 18.0 0.1 1.5 1 0 0 1 1 1 1 jmjN domain AAA_23 PF13476.6 CDJ64418.1 - 5.1 7.5 18.9 13 6.3 18.9 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 CDJ64419.1 - 2.2e-17 63.1 0.0 2.2e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SPRY PF00622.28 CDJ64420.1 - 0.19 11.9 0.2 30 4.7 0.0 3.6 4 0 0 4 4 4 0 SPRY domain Helicase_C PF00271.31 CDJ64421.1 - 1.7e-06 28.3 0.0 1.7e-06 28.3 0.0 4.2 6 0 0 6 6 6 2 Helicase conserved C-terminal domain SUIM_assoc PF16619.5 CDJ64421.1 - 0.045 13.8 0.1 0.045 13.8 0.1 31.5 22 8 4 26 26 26 0 Unstructured region C-term to UIM in Ataxin3 cNMP_binding PF00027.29 CDJ64422.1 - 1.1e-44 150.4 0.1 3.2e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Surface_antigen PF11054.8 CDJ64423.1 - 4.9e-26 91.9 0.0 1e-25 90.9 0.0 1.4 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Androgen_recep PF02166.16 CDJ64424.1 - 0.0078 15.1 3.0 0.0071 15.3 3.0 1.0 1 0 0 1 1 1 1 Androgen receptor NEMP PF10225.9 CDJ64424.1 - 0.2 11.3 0.4 0.23 11.1 0.4 1.0 1 0 0 1 1 1 0 NEMP family Spt20 PF12090.8 CDJ64424.1 - 0.23 11.1 9.4 0.22 11.1 9.4 1.1 1 0 0 1 1 1 0 Spt20 family AIF_C PF14721.6 CDJ64424.1 - 0.36 11.2 4.4 0.46 10.8 4.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4407 PF14362.6 CDJ64424.1 - 2.8 7.2 7.6 3.1 7.1 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDJ64424.1 - 7.1 5.3 7.8 9 4.9 7.8 1.2 1 0 0 1 1 1 0 Presenilin Chromo PF00385.24 CDJ64425.1 - 4.9e-10 39.2 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4834 PF16118.5 CDJ64425.1 - 0.053 14.5 0.7 0.053 14.5 0.7 9.2 4 2 0 4 4 4 0 Domain of unknown function (DUF4834) Peptidase_S49_N PF08496.10 CDJ64427.1 - 0.012 15.6 2.6 0.012 15.6 2.6 8.8 5 2 2 8 8 8 0 Peptidase family S49 N-terminal Borrelia_P83 PF05262.11 CDJ64428.1 - 0.0037 15.8 69.4 0.0046 15.5 69.4 1.0 1 0 0 1 1 1 1 Borrelia P83/100 protein LYRIC PF15686.5 CDJ64428.1 - 0.12 11.9 43.7 0.15 11.6 43.7 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Dicty_REP PF05086.12 CDJ64428.1 - 0.21 9.5 22.9 0.27 9.2 22.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SLC12 PF03522.15 CDJ64428.1 - 0.35 9.8 41.9 0.44 9.5 41.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF966 PF06136.13 CDJ64428.1 - 1.3 8.7 35.2 1.5 8.5 35.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Smg8_Smg9 PF10220.9 CDJ64428.1 - 1.9 6.7 36.7 2.1 6.5 36.7 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Hid1 PF12722.7 CDJ64428.1 - 2.1 6.4 44.8 2.5 6.1 44.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 CDJ64428.1 - 5.2 5.6 41.3 6.2 5.4 41.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HORMA PF02301.18 CDJ64429.1 - 7e-35 120.5 0.0 1.1e-34 119.9 0.0 1.3 1 1 0 1 1 1 1 HORMA domain Ribosomal_60s PF00428.19 CDJ64429.1 - 0.0051 17.4 19.6 0.19 12.3 8.1 2.3 2 0 0 2 2 2 2 60s Acidic ribosomal protein DUF3131 PF11329.8 CDJ64429.1 - 0.054 12.5 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) TFIIA PF03153.13 CDJ64430.1 - 3.7 7.4 28.3 4.3 7.2 9.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4207 PF13904.6 CDJ64431.1 - 0.0033 17.2 14.7 0.0061 16.3 2.9 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4207) DUF1635 PF07795.11 CDJ64431.1 - 0.018 14.9 2.5 0.018 14.9 2.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1635) Spt20 PF12090.8 CDJ64431.1 - 0.018 14.7 27.7 0.15 11.7 7.3 2.1 2 0 0 2 2 2 0 Spt20 family ANAPC_CDC26 PF10471.9 CDJ64431.1 - 0.022 15.6 23.0 0.036 14.9 2.9 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 CCDC117 PF15810.5 CDJ64431.1 - 0.31 11.3 9.5 0.41 10.9 0.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 117 Androgen_recep PF02166.16 CDJ64431.1 - 0.76 8.6 30.1 0.021 13.7 4.3 2.2 2 0 0 2 2 2 0 Androgen receptor TFIIA PF03153.13 CDJ64432.1 - 0.009 16.1 17.6 0.012 15.7 17.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ64432.1 - 0.011 15.7 6.5 0.011 15.7 6.5 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SRP-alpha_N PF04086.13 CDJ64432.1 - 3.4 7.5 12.8 4.1 7.2 12.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ndc1_Nup PF09531.10 CDJ64432.1 - 5 5.7 6.2 5.3 5.6 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SUIM_assoc PF16619.5 CDJ64433.1 - 0.012 15.7 7.7 0.012 15.7 7.7 4.4 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2828 PF11443.8 CDJ64433.1 - 0.45 8.5 7.4 0.63 8.1 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Calsarcin PF05556.11 CDJ64433.1 - 0.61 9.6 5.9 0.99 8.9 5.9 1.3 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) FAM60A PF15396.6 CDJ64433.1 - 6.7 6.7 6.0 12 5.8 6.0 1.4 1 0 0 1 1 1 0 Protein Family FAM60A MDM10 PF12519.8 CDJ64433.1 - 7.1 5.4 8.4 9.8 4.9 8.4 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SUIM_assoc PF16619.5 CDJ64435.1 - 0.0071 16.4 0.4 0.0071 16.4 0.4 21.0 19 3 1 20 20 20 5 Unstructured region C-term to UIM in Ataxin3 ING PF12998.7 CDJ64436.1 - 1.3e-07 32.2 3.0 1.3e-07 32.2 3.0 2.4 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding DUF5479 PF17575.2 CDJ64436.1 - 0.12 12.9 3.4 0.22 12.1 3.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5479) Aminotran_5 PF00266.19 CDJ64439.1 - 1.3e-71 241.6 0.0 2e-50 171.8 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CDJ64439.1 - 6.6e-05 22.4 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CDJ64439.1 - 0.0065 15.2 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF725 PF05267.12 CDJ64439.1 - 0.1 12.6 0.5 0.22 11.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF725) tRNA-synt_2 PF00152.20 CDJ64440.1 - 1.3e-61 208.4 0.0 2.6e-61 207.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ64440.1 - 3.8e-06 26.8 0.0 1.1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2722 PF10846.8 CDJ64440.1 - 0.0044 16.0 0.9 0.0044 16.0 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Velvet PF11754.8 CDJ64440.1 - 0.0079 16.2 4.0 1 9.3 0.0 3.1 2 1 0 3 3 3 2 Velvet factor Spt20 PF12090.8 CDJ64440.1 - 0.008 15.8 2.3 0.008 15.8 2.3 1.6 2 0 0 2 2 2 1 Spt20 family SPX PF03105.19 CDJ64440.1 - 0.49 10.3 10.1 29 4.4 10.1 2.4 1 1 0 1 1 1 0 SPX domain Dynein_attach_N PF15867.5 CDJ64441.1 - 2.2e-13 49.9 0.3 5.5e-13 48.7 0.3 1.6 1 0 0 1 1 1 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 CDJ64441.1 - 7.1e-06 26.5 0.1 5.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 Rib_5-P_isom_A PF06026.14 CDJ64442.1 - 1.3e-49 168.1 0.4 2.9e-48 163.8 0.4 2.0 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) BetR PF08667.10 CDJ64442.1 - 0.02 14.9 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 BetR domain AAA_30 PF13604.6 CDJ64442.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_trans_aux PF03886.13 CDJ64442.1 - 0.068 12.8 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component TetR_N PF00440.23 CDJ64442.1 - 0.09 12.6 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family DUF4539 PF15072.6 CDJ64443.1 - 1.1e-09 38.1 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Jun PF03957.13 CDJ64444.1 - 0.22 11.3 12.2 7.5 6.4 9.5 2.8 2 0 0 2 2 2 0 Jun-like transcription factor SF3b10 PF07189.11 CDJ64445.1 - 1.9e-31 108.0 0.0 3e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) FYDLN_acid PF09538.10 CDJ64445.1 - 1.7 9.4 11.8 2.4 8.9 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DnaJ PF00226.31 CDJ64446.1 - 0.0067 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S7e PF01251.18 CDJ64447.1 - 2.9e-66 222.7 2.6 3.3e-66 222.6 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e FtsQ PF03799.15 CDJ64447.1 - 0.076 13.8 0.8 0.41 11.5 0.1 2.1 1 1 1 2 2 2 0 Cell division protein FtsQ Alba PF01918.21 CDJ64448.1 - 4.3e-08 32.9 0.0 7.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 CDJ64448.1 - 8e-05 22.6 2.4 1.1 9.2 0.1 3.2 2 2 1 3 3 3 3 Rpp20 subunit of nuclear RNase MRP and P He_PIG PF05345.12 CDJ64449.1 - 0.026 14.7 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 Putative Ig domain Peptidase_M8 PF01457.16 CDJ64449.1 - 0.053 12.2 0.3 11 4.6 0.0 3.0 3 0 0 3 3 3 0 Leishmanolysin Dus PF01207.17 CDJ64450.1 - 4e-45 154.2 0.1 7.5e-36 123.8 0.2 2.3 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) ABC1 PF03109.16 CDJ64454.1 - 1.2e-14 54.5 0.0 1.6e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 ABC1 family LRR_4 PF12799.7 CDJ64456.1 - 2.6e-08 34.0 5.0 2.8e-05 24.4 0.5 3.2 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ64456.1 - 7e-06 25.7 4.2 0.046 13.8 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 CDJ64456.1 - 0.00033 20.8 2.3 14 6.7 0.0 4.7 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_8 PF13855.6 CDJ64456.1 - 0.00046 19.9 4.6 0.08 12.7 0.4 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 CDJ64456.1 - 0.017 14.6 0.4 0.031 13.8 0.4 1.4 1 1 0 1 1 1 0 Leucine-rich repeat SIS PF01380.22 CDJ64457.1 - 2.1e-36 124.7 0.3 9.5e-19 67.5 0.0 2.6 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 CDJ64457.1 - 4e-20 72.4 0.0 8.2e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CDJ64457.1 - 5.1e-16 58.7 0.0 9.3e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CDJ64457.1 - 1.7e-05 23.9 0.1 3.4e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II FA_desaturase PF00487.24 CDJ64458.1 - 9.3 6.0 7.9 37 4.0 8.0 1.8 1 1 0 1 1 1 0 Fatty acid desaturase LapA_dom PF06305.11 CDJ64459.1 - 6.9 6.6 6.7 3 7.7 0.0 3.4 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain RNA_GG_bind PF10258.9 CDJ64460.1 - 6.6e-25 87.0 0.1 1.2e-24 86.2 0.1 1.3 1 0 0 1 1 1 1 PHAX RNA-binding domain Vps51 PF08700.11 CDJ64462.1 - 7.1e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 tRNA-synt_2b PF00587.25 CDJ64464.1 - 4.7e-29 101.6 0.0 7.7e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Kinesin PF00225.23 CDJ64465.1 - 2.1e-93 312.9 0.7 4.8e-93 311.7 0.7 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ64465.1 - 4.8e-19 68.8 0.3 3.8e-16 59.4 0.0 3.0 1 1 0 2 2 2 2 Microtubule binding Integrase_H2C2 PF17921.1 CDJ64467.1 - 5.2e-12 45.7 0.1 1.2e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ64467.1 - 1.1e-08 35.2 0.0 1.8e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain SNF2_N PF00176.23 CDJ64469.1 - 1.2e-39 136.0 0.0 1.8e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ64469.1 - 8.1e-13 48.7 0.0 2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ64469.1 - 3.6e-05 23.8 0.0 6.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CDJ64469.1 - 0.0035 16.7 0.1 0.013 14.8 0.1 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 CDJ64469.1 - 0.014 15.0 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase HDA2-3 PF11496.8 CDJ64469.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 ECH_2 PF16113.5 CDJ64470.1 - 3.8e-33 115.4 0.0 9.5e-33 114.1 0.0 1.6 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CDJ64470.1 - 3.8e-08 33.0 0.0 7.8e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RPAP3_C PF13877.6 CDJ64470.1 - 0.013 16.1 0.4 5 7.7 0.1 2.7 2 1 1 3 3 3 0 Potential Monad-binding region of RPAP3 RNA_pol_Rpb4 PF03874.16 CDJ64470.1 - 0.11 12.9 0.2 0.18 12.2 0.2 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb4 TPR_1 PF00515.28 CDJ64471.1 - 8.4e-09 34.9 9.8 0.00032 20.4 1.6 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ64471.1 - 1.8e-08 33.9 8.4 0.00045 20.1 2.1 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ64471.1 - 2.3e-07 30.9 7.1 1.2e-06 28.6 7.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ64471.1 - 5.3e-07 29.2 2.9 5.3e-07 29.2 2.9 2.5 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 CDJ64471.1 - 0.00032 21.3 11.9 0.00032 21.3 11.9 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ64471.1 - 0.001 19.1 4.0 0.84 10.0 0.7 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ64471.1 - 0.0019 18.9 4.2 0.0019 18.9 4.2 4.7 4 1 1 5 5 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ64471.1 - 0.0084 16.2 2.6 0.3 11.2 0.3 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat DUF2478 PF10649.9 CDJ64471.1 - 0.035 13.7 0.1 1.2 8.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) TPR_7 PF13176.6 CDJ64471.1 - 0.24 11.5 5.4 1 9.5 0.8 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ64471.1 - 0.32 11.3 8.0 1.5 9.1 8.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ64471.1 - 6.1 7.5 8.1 1.4 9.5 1.7 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MutL_C PF08676.11 CDJ64472.1 - 8.2e-14 51.6 0.0 2.4e-10 40.3 0.0 4.0 4 0 0 4 4 4 2 MutL C terminal dimerisation domain HATPase_c PF02518.26 CDJ64472.1 - 4e-08 33.8 0.0 9.9e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ64472.1 - 1.2e-07 31.6 0.0 2.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 CDJ64472.1 - 1.2e-07 31.4 0.0 5.5e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain P5CR_dimer PF14748.6 CDJ64473.1 - 1.3e-36 124.9 0.2 1.9e-36 124.4 0.2 1.2 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation RT_RNaseH PF17917.1 CDJ64475.1 - 1e-27 96.4 0.0 2.5e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ64475.1 - 2.1e-26 91.8 0.0 4.3e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ64475.1 - 8.7e-15 55.0 0.1 1.1e-13 51.5 0.1 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ64475.1 - 3.4e-13 49.5 1.4 7.5e-13 48.4 1.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ64475.1 - 4.6e-05 23.6 1.9 9.2e-05 22.6 1.3 1.8 2 0 0 2 2 2 1 H2C2 zinc finger RVT_3 PF13456.6 CDJ64475.1 - 0.0035 17.2 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like Herpes_TK_C PF08465.10 CDJ64475.1 - 0.071 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal RVT_1 PF00078.27 CDJ64476.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Hamartin PF04388.12 CDJ64478.1 - 7.3 5.1 38.9 10 4.6 38.9 1.3 1 0 0 1 1 1 0 Hamartin protein LicD PF04991.13 CDJ64479.1 - 8.8 6.4 11.4 12 5.9 11.4 1.3 1 0 0 1 1 1 0 LicD family SARAF PF06682.12 CDJ64480.1 - 0.015 14.9 12.0 0.041 13.5 12.0 1.7 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF755 PF05501.11 CDJ64480.1 - 0.057 13.7 36.4 0.83 9.9 13.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Miga PF10265.9 CDJ64480.1 - 0.31 10.0 15.3 0.52 9.2 15.3 1.3 1 0 0 1 1 1 0 Mitoguardin CBP_BcsG PF11658.8 CDJ64480.1 - 0.71 8.2 7.6 0.3 9.4 4.7 1.7 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsG SR-25 PF10500.9 CDJ64480.1 - 0.83 9.2 44.4 0.73 9.4 17.7 2.4 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Plasmodium_Vir PF05795.11 CDJ64480.1 - 1.3 8.4 9.7 1.6 8.1 9.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.16 CDJ64480.1 - 1.4 8.9 9.6 2.6 8.1 9.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 CDJ64480.1 - 2.4 6.9 17.4 3.4 6.4 17.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain EphA2_TM PF14575.6 CDJ64480.1 - 5.9 7.8 9.7 37 5.3 6.0 3.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PAP1 PF08601.10 CDJ64480.1 - 6.5 6.4 30.0 53 3.4 30.0 2.0 1 1 0 1 1 1 0 Transcription factor PAP1 Pap_E4 PF02711.14 CDJ64480.1 - 9.3 7.3 18.7 12 6.9 6.5 2.4 2 0 0 2 2 2 0 E4 protein SR-25 PF10500.9 CDJ64481.1 - 0.014 15.1 28.4 0.014 15.1 28.4 3.0 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.13 CDJ64481.1 - 3 6.8 41.8 3.7 6.5 41.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mitofilin PF09731.9 CDJ64481.1 - 3.4 6.4 40.5 4.3 6.1 40.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PAT1 PF09770.9 CDJ64481.1 - 4 5.6 52.1 4.4 5.5 52.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SRP-alpha_N PF04086.13 CDJ64481.1 - 5.9 6.7 45.9 7.8 6.3 45.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TFIIF_alpha PF05793.12 CDJ64481.1 - 7.6 5.0 40.4 9.1 4.7 40.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.9 CDJ64481.1 - 9.8 4.6 52.1 16 3.9 52.1 1.3 1 0 0 1 1 1 0 Macoilin family HOASN PF14515.6 CDJ64482.1 - 0.0083 16.5 1.6 0.018 15.4 1.6 1.7 1 0 0 1 1 1 1 Haem-oxygenase-associated N-terminal helices GD_AH_C PF04295.13 CDJ64482.1 - 0.11 11.3 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus Ribosomal_60s PF00428.19 CDJ64482.1 - 3.4 8.3 13.6 1.3 9.7 10.9 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein FKBP_C PF00254.28 CDJ64484.1 - 1.9e-34 117.8 0.0 3.2e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Porin_4 PF13609.6 CDJ64484.1 - 0.0041 16.9 1.3 0.0065 16.3 1.1 1.4 1 1 0 1 1 1 1 Gram-negative porin PP-binding_2 PF14573.6 CDJ64485.1 - 1.3e-20 73.4 1.2 1.6e-20 73.1 0.1 1.7 2 0 0 2 2 2 1 Acyl-carrier DUF3824 PF12868.7 CDJ64485.1 - 0.016 15.9 12.8 0.016 15.9 12.8 10.7 8 3 2 10 10 10 0 Domain of unknwon function (DUF3824) Pinin_SDK_memA PF04696.13 CDJ64485.1 - 2.5 8.2 51.5 0.03 14.4 15.0 3.7 3 0 0 3 3 3 0 pinin/SDK/memA/ protein conserved region Glt_symporter PF03616.14 CDJ64485.1 - 4.3 5.9 4.6 11 4.6 4.6 1.6 1 0 0 1 1 1 0 Sodium/glutamate symporter Hydrolase_4 PF12146.8 CDJ64486.1 - 1.1e-16 60.9 0.1 2.1e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ64486.1 - 1e-07 32.8 0.0 1.8e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 CDJ64486.1 - 1.8e-05 23.6 0.2 0.00052 18.8 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 CDJ64486.1 - 9.2e-05 22.2 3.5 0.072 12.7 0.2 2.6 1 1 2 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CDJ64486.1 - 0.003 17.4 1.7 0.02 14.7 0.8 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 CDJ64486.1 - 0.011 15.2 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family PGAP1 PF07819.13 CDJ64486.1 - 0.012 15.4 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 CDJ64486.1 - 0.024 14.5 0.1 0.06 13.2 0.1 1.7 2 0 0 2 2 2 0 Lipase (class 3) Apc15p PF05841.11 CDJ64486.1 - 0.029 15.2 1.7 0.042 14.6 1.7 1.2 1 0 0 1 1 1 0 Apc15p protein Peptidase_S9 PF00326.21 CDJ64486.1 - 0.046 13.2 0.1 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 CDJ64486.1 - 0.057 13.5 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 CDJ64486.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family CCDC24 PF15669.5 CDJ64486.1 - 0.078 12.8 3.3 0.11 12.4 3.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Abhydrolase_3 PF07859.13 CDJ64486.1 - 0.2 11.5 0.3 0.35 10.7 0.3 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold MRI PF15325.6 CDJ64486.1 - 0.42 11.7 4.1 0.71 11.0 4.1 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection Macoilin PF09726.9 CDJ64486.1 - 1.1 7.8 11.5 1.3 7.5 11.5 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 CDJ64486.1 - 1.4 7.1 14.9 1.7 6.8 14.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 CDJ64486.1 - 1.8 7.3 12.5 2.6 6.8 12.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PIG-S PF10510.9 CDJ64487.1 - 0.00044 19.2 12.3 0.059 12.2 0.2 4.1 3 1 0 3 3 3 3 Phosphatidylinositol-glycan biosynthesis class S protein TAF4 PF05236.14 CDJ64487.1 - 0.13 12.0 0.1 0.13 12.0 0.1 3.8 5 0 0 5 5 5 0 Transcription initiation factor TFIID component TAF4 family Peptidase_S8 PF00082.22 CDJ64487.1 - 0.14 11.4 1.9 0.41 9.9 1.9 1.7 1 0 0 1 1 1 0 Subtilase family Herpes_pp85 PF04637.12 CDJ64487.1 - 0.91 7.9 3.4 1.7 7.0 3.4 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) MFS_1 PF07690.16 CDJ64488.1 - 9.7e-12 44.5 27.9 9.7e-12 44.5 27.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0060 PF02694.15 CDJ64488.1 - 0.0021 18.3 3.1 0.0021 18.3 3.1 3.3 3 1 1 4 4 4 1 Uncharacterised BCR, YnfA/UPF0060 family TRAP_alpha PF03896.16 CDJ64488.1 - 0.06 12.6 0.2 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Adeno_E4_34 PF04528.13 CDJ64488.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region DAD PF02109.16 CDJ64488.1 - 0.29 11.5 5.6 1.2 9.5 5.6 2.2 1 1 0 1 1 1 0 DAD family RskA PF10099.9 CDJ64488.1 - 0.71 10.1 14.3 0.65 10.3 4.9 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA BatD PF13584.6 CDJ64488.1 - 1.3 7.8 2.8 17 4.0 0.1 2.1 2 0 0 2 2 2 0 Oxygen tolerance NEMP PF10225.9 CDJ64488.1 - 2 8.0 9.7 0.029 14.0 1.3 2.2 2 1 0 2 2 2 0 NEMP family SOBP PF15279.6 CDJ64491.1 - 0.71 10.4 10.9 0.78 10.3 10.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 CDJ64491.1 - 5 5.7 10.1 5 5.7 10.1 1.1 1 0 0 1 1 1 0 Hamartin protein PAT1 PF09770.9 CDJ64491.1 - 7.5 4.7 15.1 7.8 4.6 15.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.8 CDJ64492.1 - 0.07 12.1 60.0 0.38 9.7 1.9 2.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PA26 PF04636.13 CDJ64492.1 - 0.22 10.4 13.1 0.48 9.3 13.1 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) AAA_23 PF13476.6 CDJ64492.1 - 0.22 12.0 11.5 0.47 10.9 11.5 1.5 1 0 0 1 1 1 0 AAA domain DUF2052 PF09747.9 CDJ64493.1 - 1e-27 97.6 74.3 1.6e-16 61.1 20.5 4.3 2 1 2 4 4 4 3 Coiled-coil domain containing protein (DUF2052) SR-25 PF10500.9 CDJ64493.1 - 0.0034 17.0 16.1 0.0034 17.0 16.1 4.7 3 1 2 5 5 5 3 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ64493.1 - 0.073 11.9 0.1 0.073 11.9 0.1 3.8 1 1 1 2 2 2 0 Golgi-body localisation protein domain RskA PF10099.9 CDJ64494.1 - 3.6e-06 27.4 5.6 3.6e-06 27.4 5.6 4.5 1 1 2 3 3 1 1 Anti-sigma-K factor rskA Macoilin PF09726.9 CDJ64494.1 - 1.5e-05 23.8 21.3 1.5e-05 23.8 21.3 3.4 2 1 1 3 3 2 1 Macoilin family K_channel_TID PF07941.11 CDJ64494.1 - 0.021 15.2 3.1 0.021 15.2 3.1 8.1 5 3 2 7 7 3 0 Potassium channel Kv1.4 tandem inactivation domain Lact-deh-memb PF09330.11 CDJ64494.1 - 0.095 12.0 2.8 0.2 11.0 2.8 1.5 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding LON_substr_bdg PF02190.16 CDJ64494.1 - 0.18 11.7 5.6 0.47 10.3 5.6 1.7 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain DUF4419 PF14388.6 CDJ64494.1 - 0.22 10.9 5.1 0.49 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4419) Tweety PF04906.13 CDJ64494.1 - 0.84 8.2 8.8 1.7 7.2 8.8 1.5 1 0 0 1 1 1 0 Tweety AAA_23 PF13476.6 CDJ64494.1 - 0.88 10.0 22.7 0.21 12.0 12.6 2.9 3 0 0 3 3 3 0 AAA domain DUF445 PF04286.12 CDJ64494.1 - 0.97 9.2 18.6 0.088 12.6 11.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) AI-2E_transport PF01594.16 CDJ64494.1 - 3.4 6.7 4.2 6.5 5.8 4.2 1.5 1 0 0 1 1 1 0 AI-2E family transporter PIN_8 PF18476.1 CDJ64494.1 - 3.6 7.4 15.5 1.3 8.9 10.7 2.4 2 0 0 2 2 2 0 PIN like domain DUF1664 PF07889.12 CDJ64494.1 - 4.2 7.4 25.4 2.3 8.3 15.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) dCache_2 PF08269.11 CDJ64494.1 - 4.6 6.3 13.1 9.1 5.4 13.1 1.4 1 0 0 1 1 1 0 Cache domain RNase_J_C PF17770.1 CDJ64494.1 - 4.9 8.3 6.5 4.6 8.4 2.4 2.9 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain RB_A PF01858.17 CDJ64494.1 - 6.1 6.6 13.4 3.7 7.3 8.2 2.5 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain DUF2115 PF09888.9 CDJ64494.1 - 7.7 7.0 12.0 4.7 7.7 8.1 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF1645 PF07816.11 CDJ64495.1 - 1.1 9.8 7.6 1.6 9.2 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DUF515 PF04415.12 CDJ64495.1 - 8.2 4.7 5.7 11 4.3 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Spt20 PF12090.8 CDJ64496.1 - 0.0046 16.6 8.5 0.007 16.0 8.5 1.2 1 0 0 1 1 1 1 Spt20 family PMI_typeI PF01238.21 CDJ64496.1 - 0.0094 15.2 0.9 0.013 14.7 0.9 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I DUF2722 PF10846.8 CDJ64496.1 - 0.017 14.1 2.5 0.024 13.6 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF3073 PF11273.8 CDJ64496.1 - 0.043 14.5 2.3 0.11 13.2 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) SUIM_assoc PF16619.5 CDJ64496.1 - 0.12 12.5 10.2 0.077 13.1 8.0 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 KCNQ2_u3 PF16642.5 CDJ64497.1 - 1.1 10.3 5.2 0.5 11.4 2.8 1.6 1 1 1 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 DUF4148 PF13663.6 CDJ64498.1 - 1.2 9.4 11.7 1 9.6 1.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Pacs-1 PF10254.9 CDJ64498.1 - 5.2 5.9 5.5 8.2 5.3 5.5 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein RskA PF10099.9 CDJ64500.1 - 0.0062 16.9 1.5 0.0062 16.9 1.5 8.8 1 1 3 4 4 4 1 Anti-sigma-K factor rskA FUSC-like PF12805.7 CDJ64501.1 - 0.047 12.8 16.1 0.065 12.3 16.0 1.3 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS CemA PF03040.14 CDJ64501.1 - 3 7.7 5.0 4 7.3 5.0 1.2 1 0 0 1 1 1 0 CemA family Orf78 PF06024.12 CDJ64502.1 - 1.5 9.2 6.3 6.2 7.2 0.2 2.4 2 0 0 2 2 2 0 Orf78 (ac78) OAD_gamma PF04277.13 CDJ64504.1 - 0.0076 16.8 0.7 0.0076 16.8 0.7 3.1 3 0 0 3 3 3 1 Oxaloacetate decarboxylase, gamma chain AF-4 PF05110.13 CDJ64505.1 - 0.00012 20.4 9.0 0.00014 20.2 9.0 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein DUF3446 PF11928.8 CDJ64505.1 - 0.0025 18.1 3.4 0.0044 17.3 3.4 1.5 1 0 0 1 1 1 1 Early growth response N-terminal domain Spt20 PF12090.8 CDJ64505.1 - 0.0027 17.4 2.3 0.0037 16.9 2.3 1.1 1 0 0 1 1 1 1 Spt20 family DUF4667 PF15700.5 CDJ64505.1 - 0.0062 16.7 5.2 0.0085 16.2 5.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) Lin-8 PF03353.15 CDJ64505.1 - 0.027 14.0 1.6 0.036 13.6 1.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CCDC106 PF15794.5 CDJ64505.1 - 0.031 14.0 3.5 0.045 13.5 3.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TFIIA PF03153.13 CDJ64505.1 - 0.033 14.2 2.8 0.039 13.9 2.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pep1_7 PF17232.2 CDJ64505.1 - 0.097 13.1 9.2 26 5.3 9.2 3.0 2 1 0 2 2 2 0 Elicitor peptide 1-7 ECSIT PF06239.11 CDJ64505.1 - 0.13 11.4 0.4 1.6 7.8 0.0 2.0 1 1 1 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway Macoilin PF09726.9 CDJ64505.1 - 0.48 8.9 3.8 0.67 8.4 3.8 1.2 1 0 0 1 1 1 0 Macoilin family DUF4598 PF15370.6 CDJ64505.1 - 3.6 8.1 7.5 8.2 6.9 7.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4598) IMUP PF15761.5 CDJ64506.1 - 0.039 14.6 9.8 0.98 10.1 0.4 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein Dehydrin PF00257.19 CDJ64506.1 - 6.1 7.4 14.7 2.1 8.9 0.4 2.2 2 0 0 2 2 2 0 Dehydrin Acetyltransf_1 PF00583.25 CDJ64507.1 - 4.7e-12 46.2 0.0 6.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ64507.1 - 9e-08 32.1 0.0 9e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ64507.1 - 2.6e-07 31.0 0.0 4.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ64507.1 - 0.0084 16.1 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Spt20 PF12090.8 CDJ64507.1 - 0.12 12.0 15.6 0.14 11.7 15.6 1.1 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ64507.1 - 7 5.4 16.5 9.4 4.9 16.5 1.1 1 0 0 1 1 1 0 Androgen receptor TMEM208_SND2 PF05620.11 CDJ64507.1 - 7.7 6.3 6.6 13 5.5 6.6 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 SR-25 PF10500.9 CDJ64508.1 - 0.00094 18.9 3.2 0.00094 18.9 3.2 5.2 2 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein Filament_head PF04732.14 CDJ64508.1 - 1.8 9.5 18.5 1.5 9.7 1.4 2.9 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Chorein_N PF12624.7 CDJ64509.1 - 0.026 14.6 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 N-terminal region of Chorein or VPS13 SLC12 PF03522.15 CDJ64510.1 - 0.57 9.1 49.7 0.19 10.7 26.1 2.0 2 0 0 2 2 2 0 Solute carrier family 12 DUF5427 PF10310.9 CDJ64510.1 - 0.79 8.6 54.0 0.26 10.2 29.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5427) DUF3807 PF12720.7 CDJ64510.1 - 1.9 8.7 60.4 2.1 8.6 33.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) PTPRCAP PF15713.5 CDJ64510.1 - 2.2 8.6 47.2 4.6 7.5 26.1 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF4628 PF15429.6 CDJ64510.1 - 3.1 7.4 36.5 4.5 6.9 11.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) VIT1 PF01988.19 CDJ64510.1 - 4.5 7.1 30.1 4.2 7.2 9.8 2.1 2 0 0 2 2 2 0 VIT family Lin-8 PF03353.15 CDJ64510.1 - 5.4 6.5 58.7 3.9 6.9 31.2 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist FAM60A PF15396.6 CDJ64510.1 - 5.5 6.9 42.3 4.2 7.3 23.3 2.2 2 0 0 2 2 2 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ64510.1 - 5.8 6.7 52.1 1.3 8.8 27.6 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ64510.1 - 6.3 5.5 62.5 1.9 7.1 35.3 2.0 2 0 0 2 2 2 0 Presenilin Gti1_Pac2 PF09729.9 CDJ64510.1 - 8.8 6.4 43.1 1 9.4 22.3 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Caldesmon PF02029.15 CDJ64510.1 - 8.9 4.9 54.8 13 4.5 54.8 1.2 1 0 0 1 1 1 0 Caldesmon HTH_30 PF13556.6 CDJ64511.1 - 0.067 13.0 1.4 27 4.7 0.4 3.4 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain IMUP PF15761.5 CDJ64511.1 - 4.9 7.9 18.2 1.4 9.6 10.9 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein cwf18 PF08315.12 CDJ64512.1 - 2e-25 90.0 0.8 2e-25 90.0 0.8 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor DUF866 PF05907.13 CDJ64513.1 - 9.8e-35 119.7 0.0 1.1e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) LMBR1 PF04791.16 CDJ64514.1 - 0.59 9.0 2.4 0.78 8.6 2.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spt20 PF12090.8 CDJ64514.1 - 1.3 8.6 38.1 0.35 10.4 4.4 2.5 2 0 0 2 2 2 0 Spt20 family DUF4770 PF15994.5 CDJ64514.1 - 9.9 6.4 17.5 3.8 7.7 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Borrelia_P83 PF05262.11 CDJ64515.1 - 0.39 9.1 23.2 0.43 9.0 23.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF572 PF04502.13 CDJ64515.1 - 0.54 9.8 21.2 0.63 9.6 21.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S8 PF00082.22 CDJ64515.1 - 1.3 8.2 13.5 1.6 7.9 13.5 1.2 1 0 0 1 1 1 0 Subtilase family Macoilin PF09726.9 CDJ64515.1 - 8.3 4.8 30.3 13 4.2 30.3 1.4 1 0 0 1 1 1 0 Macoilin family PP2C PF00481.21 CDJ64516.1 - 5.8e-16 58.9 0.0 7.2e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3439 PF11921.8 CDJ64517.1 - 0.005 16.8 13.3 0.0092 15.9 13.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.17 CDJ64517.1 - 0.0064 16.5 16.5 0.0064 16.5 16.5 1.8 2 0 0 2 2 2 1 Mucin-like glycoprotein SSP160 PF06933.11 CDJ64517.1 - 0.0089 14.3 12.4 0.011 14.0 12.4 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 RanGAP1_C PF07834.11 CDJ64517.1 - 0.15 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 RanGAP1 C-terminal domain FSA_C PF10479.9 CDJ64517.1 - 0.28 9.3 2.1 0.39 8.8 2.1 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sporozoite_P67 PF05642.11 CDJ64517.1 - 1.4 6.9 3.7 1.9 6.5 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEM154 PF15102.6 CDJ64517.1 - 1.9 8.4 4.1 4 7.3 4.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family TFIIA PF03153.13 CDJ64518.1 - 0.0039 17.2 6.0 0.0039 17.2 6.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ64518.1 - 0.037 12.6 4.1 0.041 12.5 4.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF4179 PF13786.6 CDJ64518.1 - 0.09 13.3 0.6 0.13 12.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Presenilin PF01080.17 CDJ64518.1 - 0.38 9.5 7.0 0.37 9.5 7.0 1.1 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 CDJ64518.1 - 0.54 10.1 10.9 0.62 9.9 10.9 1.2 1 0 0 1 1 1 0 SPX domain Roughex PF06020.11 CDJ64518.1 - 0.86 8.6 7.2 1.2 8.2 7.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Med3 PF11593.8 CDJ64518.1 - 1.6 7.9 16.5 2.2 7.4 16.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SR-25 PF10500.9 CDJ64518.1 - 2.5 7.7 32.5 0.048 13.3 11.6 2.4 3 0 0 3 3 2 0 Nuclear RNA-splicing-associated protein TipE PF16972.5 CDJ64518.1 - 4.7 6.3 5.0 5.3 6.1 5.0 1.3 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Spt20 PF12090.8 CDJ64518.1 - 6.3 6.3 12.2 8.7 5.9 12.2 1.2 1 0 0 1 1 1 0 Spt20 family GREB1 PF15782.5 CDJ64518.1 - 7.3 3.6 8.3 7.9 3.4 8.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Secretogranin_V PF05281.11 CDJ64519.1 - 0.077 12.6 1.0 0.08 12.6 1.0 1.1 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) DUF2057 PF09829.9 CDJ64519.1 - 0.23 11.6 3.5 0.3 11.2 3.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF1631 PF07793.11 CDJ64519.1 - 0.41 9.0 6.4 0.42 9.0 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) CCDC53 PF10152.9 CDJ64519.1 - 0.89 10.0 3.9 1.1 9.6 3.9 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3138 PF11336.8 CDJ64519.1 - 5.5 5.5 7.8 7.6 5.0 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) bcl-2I13 PF12201.8 CDJ64520.1 - 0.49 10.3 6.3 0.7 9.8 6.2 1.3 1 1 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing SPX PF03105.19 CDJ64522.1 - 0.0079 16.2 4.7 0.0097 15.9 4.7 1.1 1 0 0 1 1 1 1 SPX domain PseudoU_synth_2 PF00849.22 CDJ64522.1 - 0.15 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA pseudouridylate synthase Apt1 PF10351.9 CDJ64522.1 - 0.16 10.8 1.7 0.18 10.6 1.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ64522.1 - 0.94 7.9 3.8 1.5 7.3 3.8 1.4 1 0 0 1 1 1 0 Macoilin family RRP36 PF06102.12 CDJ64523.1 - 3e-11 43.6 25.5 3.4e-11 43.4 25.5 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 DEK_C PF08766.11 CDJ64523.1 - 0.012 15.5 3.5 0.012 15.5 3.5 1.6 2 0 0 2 2 2 0 DEK C terminal domain Coat_F PF07875.12 CDJ64523.1 - 0.44 10.8 4.3 1.7 8.9 0.4 2.2 2 0 0 2 2 2 0 Coat F domain LST1 PF05083.13 CDJ64523.1 - 1.5 9.2 7.7 0.24 11.7 0.5 2.6 1 1 2 3 3 3 0 LST-1 protein CCSAP PF15748.5 CDJ64523.1 - 5.1 7.2 21.7 5.9 7.0 21.7 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF1707 PF08044.11 CDJ64523.1 - 5.2 7.2 8.6 23 5.1 4.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1707) LCIB_C_CA PF18599.1 CDJ64523.1 - 5.4 6.2 5.8 5.4 6.2 5.1 1.3 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases SMC_N PF02463.19 CDJ64524.1 - 1.8e-23 83.1 0.1 4.2e-23 81.9 0.1 1.6 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ64524.1 - 9e-13 49.2 0.0 9e-13 49.2 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_21 PF13304.6 CDJ64524.1 - 5.1e-06 26.5 0.1 1.3e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDJ64524.1 - 7.2e-06 26.0 0.2 7.2e-06 26.0 0.2 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CDJ64524.1 - 1.1e-05 25.1 0.0 2.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tcf25 PF04910.14 CDJ64524.1 - 0.00082 18.6 2.2 0.0011 18.1 2.2 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 SR-25 PF10500.9 CDJ64524.1 - 0.0012 18.5 31.7 0.021 14.4 12.2 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein ABC_tran PF00005.27 CDJ64524.1 - 0.031 14.8 0.2 0.031 14.8 0.2 3.3 3 2 0 3 3 2 0 ABC transporter IstB_IS21 PF01695.17 CDJ64524.1 - 0.034 13.9 1.2 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 CDJ64524.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.8 2 1 1 3 3 3 0 Helicase HerA, central domain Sin_N PF04801.13 CDJ64524.1 - 0.71 9.0 20.7 0.008 15.4 13.3 1.6 2 0 0 2 2 2 0 Sin-like protein conserved region Herpes_pp85 PF04637.12 CDJ64524.1 - 6 5.2 9.3 11 4.4 9.3 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PARG_cat PF05028.14 CDJ64525.1 - 1.7e-28 99.9 0.0 2.2e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF2523 PF10734.9 CDJ64525.1 - 0.0051 17.4 0.9 0.0084 16.7 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2523) NMN_transporter PF04973.12 CDJ64525.1 - 0.016 15.1 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter DUF4134 PF13572.6 CDJ64525.1 - 0.061 13.6 0.0 0.089 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) AAA PF00004.29 CDJ64526.1 - 1.7e-09 38.2 0.3 6.5e-05 23.4 0.0 3.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Otopetrin PF03189.13 CDJ64526.1 - 2.5e-05 23.3 0.0 0.0063 15.4 0.7 3.9 2 2 0 2 2 2 1 Otopetrin Dehydrin PF00257.19 CDJ64526.1 - 0.00059 20.4 5.2 0.00059 20.4 5.2 12.3 9 4 2 11 11 11 1 Dehydrin AAA_5 PF07728.14 CDJ64526.1 - 0.029 14.4 0.0 0.098 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDJ64526.1 - 0.038 14.5 0.0 1.2 9.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CDJ64526.1 - 0.2 11.5 3.4 0.57 10.1 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SR-25 PF10500.9 CDJ64527.1 - 0.0027 17.3 6.0 0.0027 17.3 6.0 7.0 4 2 2 6 6 6 2 Nuclear RNA-splicing-associated protein EphA2_TM PF14575.6 CDJ64528.1 - 0.073 14.0 13.6 0.35 11.8 0.6 3.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Trp_oprn_chp PF09534.10 CDJ64528.1 - 4.9 6.9 62.3 0.025 14.4 32.9 2.5 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Utp14 PF04615.13 CDJ64528.1 - 5.6 5.4 46.0 8.9 4.8 46.0 1.3 1 0 0 1 1 1 0 Utp14 protein DUF755 PF05501.11 CDJ64528.1 - 6.2 7.1 49.0 0.43 10.9 15.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF755) DUF812 PF05667.11 CDJ64528.1 - 9.1 5.0 43.9 12 4.7 43.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Dehydrin PF00257.19 CDJ64528.1 - 9.2 6.8 63.8 0.83 10.2 18.3 3.1 2 1 1 3 3 3 0 Dehydrin DUF4667 PF15700.5 CDJ64529.1 - 0.00011 22.4 3.6 0.00014 22.1 3.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) Apt1 PF10351.9 CDJ64529.1 - 0.036 12.9 3.3 0.038 12.9 3.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peroxin-3 PF04882.12 CDJ64529.1 - 0.05 12.6 2.8 0.058 12.4 2.8 1.0 1 0 0 1 1 1 0 Peroxin-3 SPX PF03105.19 CDJ64529.1 - 0.62 9.9 13.8 0.72 9.7 13.8 1.0 1 0 0 1 1 1 0 SPX domain Lin-8 PF03353.15 CDJ64529.1 - 1.4 8.4 5.8 3.2 7.2 5.8 1.6 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CDJ64530.1 - 0.11 12.1 5.7 0.13 11.9 5.7 1.2 1 0 0 1 1 1 0 Spt20 family Orf78 PF06024.12 CDJ64530.1 - 4.2 7.7 7.3 6.3 7.2 0.0 2.5 3 0 0 3 3 3 0 Orf78 (ac78) BatD PF13584.6 CDJ64530.1 - 7.9 5.2 16.4 15 4.3 12.3 2.0 2 0 0 2 2 2 0 Oxygen tolerance Ndc1_Nup PF09531.10 CDJ64531.1 - 0.26 9.9 29.1 0.022 13.5 24.8 1.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ64531.1 - 8.7 5.0 40.5 0.3 9.8 34.6 1.4 2 0 0 2 2 2 0 Presenilin DUF1840 PF08895.11 CDJ64533.1 - 0.12 12.7 0.2 0.28 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) SPX PF03105.19 CDJ64533.1 - 0.16 11.9 13.9 0.2 11.5 13.9 1.1 1 0 0 1 1 1 0 SPX domain Cwf_Cwc_15 PF04889.12 CDJ64533.1 - 0.47 10.2 2.6 0.65 9.7 0.6 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein eIF-5a PF01287.20 CDJ64534.1 - 8.2e-25 86.7 0.1 1.2e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CDJ64534.1 - 0.0019 18.2 0.1 0.0032 17.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain SUIM_assoc PF16619.5 CDJ64535.1 - 3.1e-05 24.0 4.4 8.6e-05 22.5 4.4 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Cpn60_TCP1 PF00118.24 CDJ64536.1 - 9.4e-122 407.1 0.5 9.7e-78 262.0 0.0 3.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family DUF3807 PF12720.7 CDJ64537.1 - 9.5 6.5 38.9 12 6.1 38.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) FapA PF03961.13 CDJ64538.1 - 3.6 6.1 6.2 0.81 8.2 0.9 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A MutS_II PF05188.17 CDJ64538.1 - 5.3 7.3 6.7 1.1 9.6 1.1 2.4 2 0 0 2 2 2 0 MutS domain II Paralemmin PF03285.15 CDJ64538.1 - 9.7 5.7 9.6 0.39 10.3 3.1 2.0 2 0 0 2 2 2 0 Paralemmin DUF4667 PF15700.5 CDJ64539.1 - 0.0028 17.8 14.8 0.0034 17.5 14.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) Secretin_N_2 PF07655.13 CDJ64539.1 - 0.021 15.4 14.2 0.036 14.6 14.2 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Lin-8 PF03353.15 CDJ64539.1 - 0.19 11.2 9.2 0.25 10.9 9.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AF-4 PF05110.13 CDJ64539.1 - 0.22 9.5 23.7 0.27 9.3 23.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RSRP PF17069.5 CDJ64539.1 - 0.5 9.9 22.3 0.66 9.5 22.3 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Macoilin PF09726.9 CDJ64539.1 - 0.68 8.4 14.9 0.77 8.3 14.9 1.0 1 0 0 1 1 1 0 Macoilin family BPS1 PF05633.11 CDJ64539.1 - 1 8.3 7.6 1.3 8.0 7.6 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related TFIIA PF03153.13 CDJ64539.1 - 1 9.3 19.3 1.3 8.9 19.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ64539.1 - 1.4 8.8 18.0 1.6 8.6 18.0 1.1 1 0 0 1 1 1 0 SPX domain Miga PF10265.9 CDJ64539.1 - 2.5 7.0 13.4 2.9 6.8 13.4 1.1 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 CDJ64539.1 - 2.6 6.8 15.0 3.1 6.6 15.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4106 PF13388.6 CDJ64539.1 - 3.2 6.9 12.3 4.2 6.5 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Plasmodium_Vir PF05795.11 CDJ64539.1 - 3.8 6.8 6.2 4.7 6.5 6.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_S64 PF08192.11 CDJ64539.1 - 4.9 5.5 12.7 5.5 5.4 12.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 HSD3 PF15244.6 CDJ64539.1 - 5.6 6.4 15.6 6.8 6.1 15.6 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Herpes_pp85 PF04637.12 CDJ64539.1 - 5.9 5.2 16.2 7.1 4.9 16.2 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) TyrRSs_C PF16714.5 CDJ64540.1 - 0.11 12.2 0.5 0.33 10.8 0.5 1.7 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain DUF678 PF05077.12 CDJ64541.1 - 0.26 11.4 1.0 0.39 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF678) His_Phos_2 PF00328.22 CDJ64543.1 - 0.013 14.8 0.0 3 7.1 0.0 2.5 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 CDJ64544.1 - 2.1e-31 109.3 3.0 4.4e-17 62.3 0.0 4.0 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ64544.1 - 4.1e-14 52.5 0.0 4.3e-08 32.8 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase MAR_sialic_bdg PF10564.9 CDJ64547.1 - 4.5e-49 164.4 24.2 2.8e-16 59.3 1.8 4.3 4 0 0 4 4 4 4 Sialic-acid binding micronemal adhesive repeat ProRS-C_1 PF09180.11 CDJ64547.1 - 0.061 13.5 0.4 0.061 13.5 0.4 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal MAR_sialic_bdg PF10564.9 CDJ64548.1 - 1e-48 163.3 23.8 1.6e-17 63.3 1.8 4.2 4 0 0 4 4 4 4 Sialic-acid binding micronemal adhesive repeat CPSF_A PF03178.15 CDJ64549.1 - 1.8e-16 60.4 0.0 3.2e-10 39.8 0.0 3.4 4 0 0 4 4 4 2 CPSF A subunit region MMS1_N PF10433.9 CDJ64549.1 - 2.4e-14 52.9 1.6 7.7e-14 51.2 0.2 2.2 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term SR-25 PF10500.9 CDJ64549.1 - 0.005 16.5 10.1 0.005 16.5 10.1 12.4 12 1 1 13 13 13 5 Nuclear RNA-splicing-associated protein Syja_N PF02383.18 CDJ64550.1 - 4.6e-32 111.6 4.5 1e-30 107.2 0.1 2.2 2 0 0 2 2 2 2 SacI homology domain Ribosomal_60s PF00428.19 CDJ64550.1 - 0.16 12.6 29.4 0.62 10.7 14.2 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF4813 PF16072.5 CDJ64550.1 - 0.3 10.7 20.0 0.46 10.1 20.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DNA_pol3_delta2 PF13177.6 CDJ64551.1 - 0.0048 16.7 0.0 0.0081 16.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit WD40 PF00400.32 CDJ64552.1 - 1.5e-07 32.0 0.7 1.1 10.2 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat MACPF PF01823.19 CDJ64553.1 - 3.4e-41 141.6 0.2 3.4e-41 141.6 0.2 2.4 4 0 0 4 4 4 1 MAC/Perforin domain Baculo_PEP_C PF04513.12 CDJ64553.1 - 0.032 14.3 0.1 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RcnB PF11776.8 CDJ64555.1 - 0.024 14.7 0.2 0.053 13.6 0.2 1.6 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator RIO1 PF01163.22 CDJ64559.1 - 2.7e-30 105.4 0.3 2.3e-17 63.2 0.1 3.1 3 1 0 3 3 3 2 RIO1 family Pkinase_fungal PF17667.1 CDJ64559.1 - 5.9e-05 22.0 0.7 5.9e-05 22.0 0.7 3.2 2 2 0 2 2 2 1 Fungal protein kinase SUIM_assoc PF16619.5 CDJ64559.1 - 0.00091 19.2 6.8 0.00091 19.2 6.8 3.6 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 TAF4 PF05236.14 CDJ64559.1 - 0.0012 18.7 9.4 0.0012 18.7 9.4 5.6 4 2 2 6 6 6 1 Transcription initiation factor TFIID component TAF4 family Sin_N PF04801.13 CDJ64559.1 - 0.0015 17.8 0.0 0.0015 17.8 0.0 3.0 2 1 1 3 3 3 1 Sin-like protein conserved region NOA36 PF06524.12 CDJ64559.1 - 0.022 14.1 17.9 0.078 12.3 17.9 2.0 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 CDJ64559.1 - 0.29 11.6 19.4 0.83 10.1 18.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RIO1 PF01163.22 CDJ64560.1 - 1.6e-05 24.6 1.9 1.8e-05 24.4 1.0 1.5 1 1 1 2 2 2 1 RIO1 family Spt20 PF12090.8 CDJ64560.1 - 0.0094 15.6 19.0 0.012 15.3 19.0 1.1 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ64560.1 - 0.03 14.3 13.6 0.034 14.1 13.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ64560.1 - 0.035 13.0 15.6 0.043 12.8 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF775 PF05603.12 CDJ64560.1 - 0.086 12.4 3.3 0.1 12.1 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) TERB2 PF15101.6 CDJ64560.1 - 0.1 12.6 6.2 0.12 12.4 6.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RR_TM4-6 PF06459.12 CDJ64560.1 - 0.13 12.0 4.5 0.16 11.8 4.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex26 PF07163.12 CDJ64560.1 - 0.17 11.1 6.1 0.22 10.8 6.1 1.0 1 0 0 1 1 1 0 Pex26 protein Suf PF05843.14 CDJ64560.1 - 0.23 11.4 8.2 0.27 11.2 8.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 CDJ64560.1 - 0.78 10.7 5.4 0.98 10.4 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Roughex PF06020.11 CDJ64560.1 - 2 7.4 8.4 2.4 7.1 8.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 CDJ64560.1 - 2.2 7.0 4.6 2.5 6.8 4.6 1.0 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.12 CDJ64561.1 - 2.2 6.8 36.0 3 6.4 36.0 1.1 1 0 0 1 1 1 0 Hamartin protein Apt1 PF10351.9 CDJ64562.1 - 0.51 9.1 4.5 0.58 8.9 4.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MID_MedPIWI PF18296.1 CDJ64563.1 - 0.039 13.7 0.1 0.041 13.7 0.1 1.1 1 0 0 1 1 1 0 MID domain of medPIWI DUF1180 PF06679.12 CDJ64563.1 - 0.13 12.6 8.2 0.2 12.0 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TFIIA PF03153.13 CDJ64563.1 - 0.15 12.0 15.7 0.17 11.8 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FHIPEP PF00771.20 CDJ64563.1 - 0.43 9.0 6.7 0.52 8.7 6.7 1.2 1 0 0 1 1 1 0 FHIPEP family Suf PF05843.14 CDJ64563.1 - 0.84 9.6 4.2 1 9.3 4.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SUIM_assoc PF16619.5 CDJ64563.1 - 2.3 8.3 12.1 1.1 9.4 7.1 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 IHABP4_N PF16174.5 CDJ64563.1 - 4.1 8.0 15.4 5.9 7.5 15.4 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Spore_III_AF PF09581.10 CDJ64564.1 - 0.22 11.6 0.5 0.35 10.9 0.5 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) SUIM_assoc PF16619.5 CDJ64564.1 - 2.4 8.3 11.8 0.053 13.6 4.4 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cnd1 PF12717.7 CDJ64565.1 - 0.0016 18.5 0.2 0.36 10.8 0.0 3.6 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 zf-Nse PF11789.8 CDJ64566.1 - 0.0047 16.7 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TFIIA PF03153.13 CDJ64567.1 - 0.0068 16.4 46.2 0.0092 16.0 46.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CRISPR_assoc PF08798.11 CDJ64567.1 - 0.016 15.3 9.2 0.021 14.9 9.2 1.3 1 0 0 1 1 1 0 CRISPR associated protein Exonuc_VII_L PF02601.15 CDJ64567.1 - 0.27 10.8 16.6 0.33 10.5 16.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit RAMP4 PF06624.12 CDJ64567.1 - 0.33 11.1 0.1 0.33 11.1 0.1 2.9 3 0 0 3 3 3 0 Ribosome associated membrane protein RAMP4 PAT1 PF09770.9 CDJ64567.1 - 0.91 7.7 31.7 1.1 7.5 31.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CemA PF03040.14 CDJ64567.1 - 0.97 9.3 10.4 1.4 8.8 10.4 1.2 1 0 0 1 1 1 0 CemA family DUF3292 PF11696.8 CDJ64567.1 - 1.1 7.5 8.9 1.7 6.9 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Caldesmon PF02029.15 CDJ64567.1 - 1.3 7.7 19.4 1.8 7.2 19.4 1.1 1 0 0 1 1 1 0 Caldesmon SLC12 PF03522.15 CDJ64567.1 - 1.6 7.6 17.4 2.2 7.2 17.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 V_ATPase_I PF01496.19 CDJ64567.1 - 2.7 5.8 19.3 3.7 5.4 19.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 CDJ64567.1 - 3.3 7.5 15.6 4.4 7.1 15.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MMU163 PF17119.5 CDJ64567.1 - 3.5 6.7 9.5 0.59 9.2 4.0 2.0 1 1 1 2 2 2 0 Mitochondrial protein up-regulated during meiosis RIFIN PF02009.16 CDJ64567.1 - 3.7 7.4 15.8 6.1 6.6 15.8 1.3 1 0 0 1 1 1 0 Rifin CCSAP PF15748.5 CDJ64567.1 - 4.1 7.5 24.5 6.4 6.9 24.5 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated ALMT PF11744.8 CDJ64567.1 - 5.5 5.7 12.0 7.3 5.3 12.0 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter VIR_N PF15912.5 CDJ64567.1 - 5.6 6.5 11.4 8.7 5.8 11.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal PTPRCAP PF15713.5 CDJ64569.1 - 0.0036 17.6 17.1 0.0036 17.6 17.1 3.1 2 1 0 2 2 2 1 Protein tyrosine phosphatase receptor type C-associated RNA_pol_Rpc4 PF05132.14 CDJ64569.1 - 0.0066 16.9 13.5 0.0066 16.9 13.5 2.9 2 1 0 2 2 2 1 RNA polymerase III RPC4 Merozoite_SPAM PF07133.11 CDJ64569.1 - 7.4 6.5 43.1 4.3 7.3 21.4 2.2 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) CCSAP PF15748.5 CDJ64569.1 - 7.6 6.6 53.4 0.075 13.2 19.6 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SR-25 PF10500.9 CDJ64570.1 - 0.0076 15.9 1.7 0.0088 15.7 0.1 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DuoxA PF10204.9 CDJ64570.1 - 0.057 12.4 0.1 0.084 11.9 0.1 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor DUF1356 PF07092.12 CDJ64570.1 - 0.13 11.5 0.1 0.26 10.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) BSP_II PF05432.11 CDJ64570.1 - 0.15 11.7 0.3 16 5.1 0.0 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF2722 PF10846.8 CDJ64570.1 - 0.57 9.1 13.7 0.14 11.1 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ64570.1 - 0.59 9.7 22.2 0.23 11.0 7.9 2.2 2 0 0 2 2 2 0 Spt20 family EphA2_TM PF14575.6 CDJ64570.1 - 1.5 9.7 6.5 7.7 7.5 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain LAP1C PF05609.12 CDJ64572.1 - 0.21 10.7 23.7 0.27 10.3 23.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4551 PF15087.6 CDJ64572.1 - 5.5 5.7 20.2 7.1 5.3 20.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Utp14 PF04615.13 CDJ64572.1 - 9 4.7 33.8 11 4.5 33.8 1.0 1 0 0 1 1 1 0 Utp14 protein DUF2749 PF10907.8 CDJ64573.1 - 2.5 8.3 0.0 2.5 8.3 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2749) FHA PF00498.26 CDJ64574.1 - 1.2e-14 54.4 0.0 2.1e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain SMAP PF15477.6 CDJ64574.1 - 1.1e-11 45.5 0.0 1.1e-11 45.5 0.0 4.1 1 1 1 2 2 2 1 Small acidic protein family Yop-YscD_cpl PF16697.5 CDJ64574.1 - 0.00013 22.2 0.0 0.0062 16.8 0.0 2.6 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SR-25 PF10500.9 CDJ64574.1 - 0.0029 17.3 35.0 0.0029 17.3 35.0 3.1 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein DUF677 PF05055.12 CDJ64574.1 - 0.036 13.0 1.0 0.057 12.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Cwf_Cwc_15 PF04889.12 CDJ64574.1 - 1.4 8.6 28.1 0.026 14.2 17.1 2.4 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Activator_LAG-3 PF11498.8 CDJ64575.1 - 0.00066 18.8 0.4 0.0014 17.7 0.4 1.5 1 0 0 1 1 1 1 Transcriptional activator LAG-3 SR-25 PF10500.9 CDJ64576.1 - 0.28 10.8 19.3 0.25 10.9 13.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Afi1 PF07792.12 CDJ64577.1 - 0.00043 20.8 12.9 0.00063 20.2 12.9 1.3 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_S15 PF02129.18 CDJ64577.1 - 0.006 16.2 19.4 0.0073 15.9 19.4 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF4746 PF15928.5 CDJ64577.1 - 0.28 10.6 16.1 0.29 10.5 16.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 CDJ64577.1 - 0.51 10.1 27.2 0.66 9.7 27.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ64577.1 - 0.82 8.6 17.4 0.84 8.5 17.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 CDJ64577.1 - 1 8.1 25.4 1.2 7.9 25.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2828 PF11443.8 CDJ64577.1 - 1.1 7.3 24.1 1.1 7.2 24.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) ALMT PF11744.8 CDJ64577.1 - 1.4 7.6 19.1 1.4 7.6 19.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Membralin PF09746.9 CDJ64577.1 - 1.8 7.5 16.3 1.8 7.5 16.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein eIF-3_zeta PF05091.12 CDJ64577.1 - 1.9 7.4 37.9 2.4 7.1 37.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TCP PF03634.13 CDJ64577.1 - 1.9 9.0 28.2 2.8 8.5 28.2 1.2 1 0 0 1 1 1 0 TCP family transcription factor SID-1_RNA_chan PF13965.6 CDJ64577.1 - 2.9 6.2 13.7 2.9 6.2 13.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Cellulose_synt PF03552.14 CDJ64577.1 - 2.9 6.3 14.8 3.2 6.1 14.8 1.0 1 0 0 1 1 1 0 Cellulose synthase CSG2 PF16965.5 CDJ64577.1 - 3 6.7 14.0 2.9 6.8 14.0 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator NARP1 PF12569.8 CDJ64577.1 - 3.3 6.5 22.3 3.2 6.5 22.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Endostatin PF06482.11 CDJ64577.1 - 3.5 7.0 26.9 3.8 6.9 26.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF778 PF05608.12 CDJ64577.1 - 3.6 7.9 19.9 4.5 7.6 19.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF778) PPP4R2 PF09184.11 CDJ64577.1 - 3.7 7.1 17.1 4.3 6.9 17.1 1.1 1 0 0 1 1 1 0 PPP4R2 SpoIIP PF07454.11 CDJ64577.1 - 3.8 6.9 29.8 4.7 6.6 29.8 1.3 1 1 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PvlArgDC PF01862.16 CDJ64577.1 - 4.6 7.0 5.8 5.5 6.8 5.8 1.2 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) MCM_bind PF09739.9 CDJ64577.1 - 4.7 5.5 25.0 4.6 5.6 25.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF5427 PF10310.9 CDJ64577.1 - 4.9 6.0 32.1 5.7 5.8 32.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 CDJ64577.1 - 5 6.0 28.3 5.9 5.8 28.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ64577.1 - 5.6 5.6 37.0 6.5 5.4 37.0 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CDJ64577.1 - 6.4 4.9 26.4 6.8 4.8 26.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 CDJ64577.1 - 6.5 6.8 27.2 8.8 6.4 27.2 1.2 1 0 0 1 1 1 0 DDHD domain VIR_N PF15912.5 CDJ64577.1 - 6.6 6.2 15.7 7.1 6.1 15.7 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CCSAP PF15748.5 CDJ64577.1 - 8 6.6 36.1 9.6 6.3 36.1 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated XRN_M PF17846.1 CDJ64577.1 - 8.5 5.2 18.8 9.6 5.0 18.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain SAPS PF04499.15 CDJ64577.1 - 9.1 4.9 21.3 9.6 4.9 21.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Otopetrin PF03189.13 CDJ64577.1 - 9.3 4.9 15.9 9.1 5.0 15.9 1.2 1 0 0 1 1 1 0 Otopetrin RskA PF10099.9 CDJ64578.1 - 1.2 9.3 51.9 1.4e+04 -3.8 33.8 3.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Abhydro_lipase PF04083.16 CDJ64580.1 - 5.1e-07 29.2 0.0 3.6e-06 26.5 0.0 2.4 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Shadoo PF14999.6 CDJ64581.1 - 0.0044 17.1 3.5 0.0044 17.1 3.5 4.5 2 1 2 4 4 4 1 Shadow of prion protein, neuroprotective DUF5384 PF17358.2 CDJ64581.1 - 0.017 15.2 0.1 0.017 15.2 0.1 6.3 6 1 1 7 7 7 0 Family of unknown function (DUF5384) DUF4834 PF16118.5 CDJ64581.1 - 0.024 15.6 27.4 0.38 11.7 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) RskA PF10099.9 CDJ64581.1 - 0.095 13.0 69.0 0.067 13.5 18.0 5.0 1 1 2 3 3 3 0 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ64581.1 - 0.69 8.8 48.7 0.059 12.3 1.8 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ64582.1 - 8.6e-06 25.5 9.2 1.2e-05 25.1 9.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein FAM199X PF15814.5 CDJ64582.1 - 0.0044 16.1 9.4 0.0064 15.6 9.4 1.3 1 0 0 1 1 1 1 Protein family FAM199X Vpu PF00558.19 CDJ64582.1 - 0.18 11.6 4.2 0.3 10.9 4.2 1.3 1 0 0 1 1 1 0 Vpu protein Peptidase_S49_N PF08496.10 CDJ64582.1 - 0.73 9.9 3.2 1.1 9.3 3.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SR-25 PF10500.9 CDJ64583.1 - 8.8e-05 22.2 9.4 8.8e-05 22.2 9.4 3.1 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein SDA1 PF05285.12 CDJ64583.1 - 0.00027 20.5 1.3 0.053 12.9 0.5 2.2 2 0 0 2 2 2 2 SDA1 BRF1 PF07741.13 CDJ64583.1 - 0.0025 18.1 2.0 0.0025 18.1 2.0 3.3 4 0 0 4 4 4 1 Brf1-like TBP-binding domain CCSAP PF15748.5 CDJ64583.1 - 0.072 13.3 18.9 0.017 15.3 8.2 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated TCP PF03634.13 CDJ64583.1 - 0.89 10.1 15.4 2 8.9 7.9 2.8 2 0 0 2 2 2 0 TCP family transcription factor DUF4207 PF13904.6 CDJ64583.1 - 1.2 8.7 23.7 0.41 10.3 15.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Sec16 PF12932.7 CDJ64583.1 - 2.7 8.6 5.3 1.5 9.4 2.0 2.3 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region SOBP PF15279.6 CDJ64583.1 - 3.3 8.2 11.4 0.62 10.6 4.1 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein Velvet PF11754.8 CDJ64583.1 - 6.9 6.5 12.1 2.7 7.9 5.5 2.4 2 0 0 2 2 2 0 Velvet factor XhlA PF10779.9 CDJ64584.1 - 0.032 14.5 2.4 0.032 14.5 2.4 4.1 4 1 0 4 4 4 0 Haemolysin XhlA RyR PF02026.16 CDJ64584.1 - 0.14 12.4 2.8 11 6.2 0.2 3.3 2 1 0 2 2 2 0 RyR domain FUSC PF04632.12 CDJ64584.1 - 2.3 6.7 15.5 15 4.0 0.0 3.0 1 1 1 3 3 3 0 Fusaric acid resistance protein family NPV_P10 PF05531.12 CDJ64584.1 - 5.2 7.6 13.1 6 7.4 0.1 4.9 4 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Nas2_N PF18265.1 CDJ64585.1 - 2.9e-24 84.8 0.0 4.9e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 CDJ64585.1 - 0.00034 20.4 1.9 0.0013 18.5 0.1 2.7 2 1 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CDJ64585.1 - 0.0059 16.9 0.0 0.015 15.6 0.0 1.6 2 0 0 2 2 2 1 PDZ domain Tom22 PF04281.13 CDJ64587.1 - 2.7e-05 24.0 0.0 3.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 SK_channel PF03530.14 CDJ64587.1 - 0.075 13.0 0.0 0.085 12.9 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated SK potassium channel PFK PF00365.20 CDJ64587.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Phosphofructokinase Methyltr_RsmB-F PF01189.17 CDJ64588.1 - 6.1e-24 84.8 14.2 1.5e-19 70.4 0.0 5.1 4 1 0 4 4 4 2 16S rRNA methyltransferase RsmB/F SUIM_assoc PF16619.5 CDJ64588.1 - 5e-05 23.3 0.0 0.0048 16.9 0.0 6.8 3 3 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ64588.1 - 0.0055 17.0 7.8 0.0055 17.0 7.8 5.8 5 2 1 6 6 6 1 Anti-sigma-K factor rskA DUF4667 PF15700.5 CDJ64588.1 - 0.01 16.0 2.1 0.01 16.0 2.1 2.7 2 2 1 3 3 3 0 Domain of unknown function (DUF4667) LMBR1 PF04791.16 CDJ64588.1 - 0.37 9.6 2.5 0.72 8.7 2.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF572 PF04502.13 CDJ64588.1 - 1.5 8.4 18.2 0.02 14.5 1.4 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF572) TFIIA PF03153.13 CDJ64588.1 - 8.3 6.3 72.2 2.6 8.0 11.1 3.4 3 1 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Tubulin PF00091.25 CDJ64589.1 - 6.9e-67 225.5 0.0 9.6e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ64589.1 - 6e-51 171.9 0.3 1.6e-50 170.5 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDJ64589.1 - 0.039 13.6 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Tubulin domain Chorion_2 PF03964.15 CDJ64590.1 - 0.0016 19.2 2.7 0.0018 19.1 2.7 1.1 1 0 0 1 1 1 1 Chorion family 2 DUF3824 PF12868.7 CDJ64590.1 - 0.28 11.9 4.3 0.3 11.7 4.3 1.0 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) partial_CstF PF15861.5 CDJ64591.1 - 5.2e-08 32.6 0.9 9.4e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Partial cleavage stimulation factor domain CSTF2_hinge PF14327.6 CDJ64591.1 - 0.0029 18.0 3.5 0.0029 18.0 3.5 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 TFIIA PF03153.13 CDJ64591.1 - 1.8 8.5 20.5 1.1 9.1 19.1 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C1 PF00112.23 CDJ64592.1 - 2.5e-15 57.1 7.3 6.5e-12 46.0 0.5 2.8 2 1 1 3 3 3 2 Papain family cysteine protease CathepsinC_exc PF08773.11 CDJ64592.1 - 7.2e-14 52.1 6.9 1.1e-12 48.3 6.9 2.6 1 1 0 1 1 1 1 Cathepsin C exclusion domain tRNA-synt_2b PF00587.25 CDJ64592.1 - 2e-06 27.9 0.0 4.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Peptidase_C1_2 PF03051.15 CDJ64592.1 - 0.05 12.4 0.2 0.087 11.6 0.2 1.2 1 0 0 1 1 1 0 Peptidase C1-like family Sec3-PIP2_bind PF15277.6 CDJ64593.1 - 0.076 13.1 0.1 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_13 PF16652.5 CDJ64593.1 - 0.095 12.5 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain Thioredoxin PF00085.20 CDJ64595.1 - 2.3e-23 82.1 0.0 2.8e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ64595.1 - 9.2e-06 26.1 0.1 2e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CDJ64595.1 - 8.2e-05 22.1 0.0 0.00011 21.7 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CDJ64595.1 - 0.00028 21.0 0.0 0.00065 19.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like ERp29_N PF07912.13 CDJ64595.1 - 0.0009 19.4 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain Thioredoxin_6 PF13848.6 CDJ64595.1 - 0.0068 16.3 0.0 0.0091 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CDJ64595.1 - 0.055 13.3 0.0 0.081 12.7 0.0 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 CDJ64595.1 - 0.057 13.7 0.0 0.6 10.5 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like Redoxin PF08534.10 CDJ64595.1 - 0.063 13.0 0.0 0.093 12.4 0.0 1.3 1 1 0 1 1 1 0 Redoxin Amino_oxidase PF01593.24 CDJ64596.1 - 1e-41 143.7 3.3 4.8e-33 115.1 0.1 2.6 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase zf-CW PF07496.15 CDJ64596.1 - 2.7e-37 126.5 40.2 1.1e-12 47.8 5.6 3.7 3 0 0 3 3 3 3 CW-type Zinc Finger NAD_binding_8 PF13450.6 CDJ64596.1 - 1.5e-05 25.1 4.6 1.5e-05 25.1 4.6 3.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ64596.1 - 0.0028 16.9 0.4 0.0057 15.9 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ64596.1 - 0.012 14.8 1.6 0.024 13.9 1.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ64596.1 - 0.017 13.8 0.3 0.017 13.8 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 CDJ64596.1 - 0.042 13.1 0.2 0.092 12.0 0.2 1.5 1 0 0 1 1 1 0 Thi4 family Dynamin_M PF01031.20 CDJ64597.1 - 4.4e-86 288.6 0.0 3.2e-84 282.5 0.0 2.3 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CDJ64597.1 - 2e-52 177.6 0.0 4.3e-52 176.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CDJ64597.1 - 3.1e-30 104.2 2.4 4.8e-30 103.6 1.1 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CDJ64597.1 - 8e-06 25.9 0.0 2.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDJ64597.1 - 0.0051 17.2 0.9 0.71 10.2 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain T3SS_needle_E PF08988.10 CDJ64597.1 - 0.23 11.7 2.4 15 5.8 0.0 3.0 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle TRAM_LAG1_CLN8 PF03798.16 CDJ64599.1 - 3.1e-27 95.6 19.2 4.1e-27 95.2 19.2 1.2 1 0 0 1 1 1 1 TLC domain Pkinase PF00069.25 CDJ64601.1 - 3.1e-32 112.0 0.0 3.9e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ64601.1 - 2.3e-23 82.8 0.0 2.9e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ64601.1 - 1.8e-10 40.2 0.0 2.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ64601.1 - 0.0011 18.9 0.0 0.03 14.2 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 CDJ64601.1 - 0.026 14.7 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Pox_ser-thr_kin PF05445.11 CDJ64601.1 - 0.062 12.3 0.1 0.095 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Nsp1_C PF05064.13 CDJ64602.1 - 1.1e-12 47.8 3.5 1.1e-12 47.8 3.5 2.2 1 1 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 CDJ64602.1 - 8.3e-12 45.8 157.9 4.9e-06 27.3 24.0 7.6 1 1 5 6 6 6 5 Nucleoporin FG repeat region DUF1664 PF07889.12 CDJ64602.1 - 0.16 12.0 9.2 1.1 9.3 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FliD_C PF07195.12 CDJ64602.1 - 0.21 11.0 2.7 0.37 10.2 1.2 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus ABC_tran_CTD PF16326.5 CDJ64602.1 - 2.4 8.5 7.1 0.5 10.6 0.1 2.9 2 1 1 3 3 3 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 CDJ64602.1 - 5.5 7.0 8.6 3.4 7.7 6.0 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 CDJ64602.1 - 8.8 5.8 12.2 20 4.6 12.2 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit rve PF00665.26 CDJ64603.1 - 0.034 14.3 0.1 0.07 13.3 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain Aconitase PF00330.20 CDJ64604.1 - 4.5e-152 507.3 0.0 6.3e-152 506.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDJ64604.1 - 4.8e-42 143.4 0.0 1e-41 142.3 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain H_lectin PF09458.10 CDJ64607.1 - 0.11 12.7 0.0 0.45 10.8 0.0 2.1 1 0 0 1 1 1 0 H-type lectin domain TSP_1 PF00090.19 CDJ64608.1 - 0.0011 19.1 7.6 0.0011 19.1 7.6 3.0 2 1 0 2 2 2 1 Thrombospondin type 1 domain Septin PF00735.18 CDJ64608.1 - 0.056 12.7 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Septin Dabb PF07876.12 CDJ64608.1 - 0.096 13.3 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain TSP_1 PF00090.19 CDJ64609.1 - 1.8e-07 31.3 29.4 0.0019 18.4 0.7 6.3 5 1 0 5 5 5 4 Thrombospondin type 1 domain G-patch_2 PF12656.7 CDJ64610.1 - 3.7e-11 43.0 0.0 3.7e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 G-patch domain SR-25 PF10500.9 CDJ64610.1 - 3.8e-05 23.4 12.7 3.8e-05 23.4 12.7 3.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ64610.1 - 0.14 12.3 0.1 0.14 12.3 0.1 4.2 3 2 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 CDJ64611.1 - 0.014 15.4 2.4 0.014 15.4 2.4 4.2 4 1 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ64611.1 - 0.048 13.3 20.8 0.04 13.5 4.9 2.3 2 0 0 2 2 2 0 Spt20 family Miff PF05644.11 CDJ64611.1 - 2.8 7.5 8.7 0.083 12.5 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff TFIIA PF03153.13 CDJ64612.1 - 0.048 13.6 8.5 0.064 13.3 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rz1 PF06085.11 CDJ64612.1 - 0.064 13.0 2.3 0.2 11.5 2.3 1.8 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor FAM101 PF15068.6 CDJ64612.1 - 0.13 12.2 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 FAM101 family DUF2722 PF10846.8 CDJ64613.1 - 5.5e-06 25.6 46.8 0.00022 20.3 14.8 4.3 3 1 0 3 3 3 3 Protein of unknown function (DUF2722) Neur_chan_memb PF02932.16 CDJ64613.1 - 0.0019 18.3 0.4 0.0019 18.3 0.4 3.9 3 1 0 4 4 4 1 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 CDJ64613.1 - 0.0022 16.5 0.2 0.0022 16.5 0.2 2.7 3 0 0 3 3 3 2 dsRNA-gated channel SID-1 DUF4407 PF14362.6 CDJ64613.1 - 0.014 14.8 0.9 0.014 14.8 0.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MecA PF05389.12 CDJ64613.1 - 0.099 12.3 13.0 0.64 9.6 0.4 3.0 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) Spt20 PF12090.8 CDJ64614.1 - 0.0058 16.3 9.6 0.0064 16.1 9.6 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ64614.1 - 0.018 14.0 4.8 0.018 14.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PulG PF11773.8 CDJ64614.1 - 0.17 11.7 1.7 0.27 11.1 1.7 1.2 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin Protamine_P2 PF00841.19 CDJ64614.1 - 1.7 9.2 5.6 2.8 8.5 5.6 1.3 1 0 0 1 1 1 0 Sperm histone P2 OSCP PF00213.18 CDJ64615.1 - 3.8e-16 59.7 3.5 3.8e-16 59.7 3.5 2.0 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit AF-4 PF05110.13 CDJ64615.1 - 0.018 13.1 14.3 0.024 12.8 14.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Lin-8 PF03353.15 CDJ64615.1 - 0.025 14.2 5.2 0.031 13.9 5.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4667 PF15700.5 CDJ64615.1 - 0.038 14.1 9.0 0.061 13.4 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ64615.1 - 0.05 13.2 13.8 0.076 12.6 13.8 1.4 1 0 0 1 1 1 0 Spt20 family Apt1 PF10351.9 CDJ64615.1 - 0.065 12.1 4.6 0.068 12.0 4.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ64615.1 - 0.098 11.2 5.5 0.13 10.8 5.5 1.3 1 0 0 1 1 1 0 Macoilin family DUF1645 PF07816.11 CDJ64615.1 - 0.11 13.1 10.5 0.17 12.4 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Sporozoite_P67 PF05642.11 CDJ64615.1 - 0.11 10.6 2.1 0.15 10.2 2.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_S64 PF08192.11 CDJ64615.1 - 0.24 9.8 6.6 0.27 9.7 6.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 TAF4 PF05236.14 CDJ64615.1 - 0.51 10.0 9.0 0.39 10.4 7.9 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SPX PF03105.19 CDJ64615.1 - 0.53 10.2 9.1 0.58 10.0 9.1 1.2 1 0 0 1 1 1 0 SPX domain GREB1 PF15782.5 CDJ64615.1 - 1.2 6.1 11.5 1.5 5.9 11.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3446 PF11928.8 CDJ64615.1 - 3 8.2 20.0 0.41 11.0 15.2 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain RskA PF10099.9 CDJ64617.1 - 0.0002 21.7 8.0 0.00024 21.4 8.0 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Med3 PF11593.8 CDJ64617.1 - 0.23 10.6 22.2 0.27 10.4 22.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 CDJ64617.1 - 1.3 9.0 18.0 1.4 8.8 18.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ64617.1 - 2.3 8.1 10.5 2.6 8.0 10.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MSP1_C PF07462.11 CDJ64617.1 - 5.8 5.5 7.0 6.5 5.3 7.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus TMEM173 PF15009.6 CDJ64618.1 - 0.0024 17.1 2.7 0.0024 17.1 2.7 2.1 2 0 0 2 2 2 1 Transmembrane protein 173 DUF2339 PF10101.9 CDJ64618.1 - 0.013 14.1 1.2 0.013 14.1 1.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Phage_Mu_Gam PF07352.12 CDJ64618.1 - 0.29 11.0 6.3 0.41 10.5 6.3 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF4179 PF13786.6 CDJ64618.1 - 2.2 8.8 8.2 0.46 11.0 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) SR-25 PF10500.9 CDJ64619.1 - 0.0067 16.1 16.1 0.012 15.3 16.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ64619.1 - 0.0077 16.5 13.0 0.0077 16.5 13.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF755) RAP1 PF07218.11 CDJ64619.1 - 4.4 5.5 6.1 6.4 4.9 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF515 PF04415.12 CDJ64619.1 - 4.5 5.5 11.1 5.6 5.3 10.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF515) AF-4 PF05110.13 CDJ64619.1 - 5.2 5.0 13.9 6.7 4.7 13.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NAD_binding_4 PF07993.12 CDJ64620.1 - 6.5e-54 182.8 0.0 1.4e-53 181.7 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Sulfotransfer_3 PF13469.6 CDJ64620.1 - 1.2e-43 150.0 0.1 3.5e-43 148.5 0.1 1.9 1 0 0 1 1 1 1 Sulfotransferase family KR PF08659.10 CDJ64620.1 - 2.5e-42 144.8 0.0 1.7e-40 138.9 0.0 2.3 2 0 0 2 2 2 1 KR domain Sulfotransfer_1 PF00685.27 CDJ64620.1 - 7.2e-17 61.7 0.0 1.6e-16 60.6 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain PP-binding PF00550.25 CDJ64620.1 - 5.7e-12 45.8 0.0 1.9e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 CDJ64620.1 - 3.8e-09 36.4 0.0 3.7e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 CDJ64620.1 - 0.00018 21.0 0.1 0.0009 18.7 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Sulfotransfer_4 PF17784.1 CDJ64620.1 - 0.00033 20.5 0.3 0.0052 16.6 0.1 2.6 2 0 0 2 2 2 1 Sulfotransferase domain 3Beta_HSD PF01073.19 CDJ64620.1 - 0.075 12.0 0.0 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.16 CDJ64620.1 - 0.084 13.6 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF1331 PF07048.11 CDJ64620.1 - 0.12 12.1 0.1 0.91 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) IMCp PF12314.8 CDJ64621.1 - 1.7e-25 89.1 64.5 3.6e-25 88.1 42.0 4.7 2 2 2 4 4 4 2 Inner membrane complex protein PBAN PF05874.11 CDJ64621.1 - 0.1 12.5 0.4 0.26 11.1 0.4 1.6 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) IMCp PF12314.8 CDJ64622.1 - 3.2e-31 107.5 89.2 4.2e-20 71.8 38.7 4.2 1 1 2 3 3 3 3 Inner membrane complex protein LSM PF01423.22 CDJ64623.1 - 1.4e-15 56.7 0.9 2.3e-15 56.0 0.9 1.4 1 0 0 1 1 1 1 LSM domain RRM_1 PF00076.22 CDJ64624.1 - 7.1e-08 32.2 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AT_hook PF02178.19 CDJ64625.1 - 0.71 10.0 6.5 1.9 8.6 6.5 1.8 1 0 0 1 1 1 0 AT hook motif Nucleoside_tran PF01733.18 CDJ64626.1 - 4.2e-15 55.9 9.4 4.2e-15 55.9 9.4 1.5 2 0 0 2 2 2 1 Nucleoside transporter EGF_3 PF12947.7 CDJ64628.1 - 1.2e-05 25.4 59.6 0.00041 20.5 13.3 5.9 5 1 1 6 6 6 4 EGF domain FXa_inhibition PF14670.6 CDJ64628.1 - 0.025 14.8 8.2 0.025 14.8 8.2 6.0 5 1 1 6 6 6 0 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CDJ64628.1 - 0.11 12.7 63.6 0.61 10.3 13.3 5.8 5 0 0 5 5 5 0 Calcium-binding EGF domain DUF4083 PF13314.6 CDJ64628.1 - 0.17 11.8 0.3 0.37 10.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) cEGF PF12662.7 CDJ64628.1 - 0.49 10.4 44.0 0.12 12.3 3.9 5.8 5 1 0 5 5 5 0 Complement Clr-like EGF-like hEGF PF12661.7 CDJ64628.1 - 7.9 7.3 53.6 0.72 10.6 0.9 7.2 6 0 0 6 6 6 0 Human growth factor-like EGF CNDH2_C PF16858.5 CDJ64630.1 - 0.064 13.1 13.9 0.097 12.5 13.9 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term FAM60A PF15396.6 CDJ64630.1 - 0.14 12.2 7.9 0.21 11.6 7.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.13 CDJ64630.1 - 0.3 11.0 29.0 0.4 10.6 29.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PNISR PF15996.5 CDJ64630.1 - 0.56 10.4 27.7 1.3 9.3 27.7 1.5 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Hid1 PF12722.7 CDJ64630.1 - 0.82 7.7 21.7 1.1 7.3 21.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4175 PF13779.6 CDJ64630.1 - 2.3 6.0 37.6 3.1 5.6 37.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Zip PF02535.22 CDJ64630.1 - 3.5 6.8 6.7 4.7 6.3 6.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIF_alpha PF05793.12 CDJ64630.1 - 4.1 5.9 25.8 5.6 5.4 25.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 CDJ64630.1 - 4.9 5.2 24.4 6.4 4.9 24.4 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 CDJ64630.1 - 8.7 5.0 21.2 12 4.5 21.2 1.2 1 0 0 1 1 1 0 Presenilin AfaD PF05775.12 CDJ64631.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein CC2D2AN-C2 PF15625.6 CDJ64632.1 - 0.074 12.8 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain Macro PF01661.21 CDJ64634.1 - 1.1e-09 38.3 0.0 3e-06 27.3 0.0 3.1 2 0 0 2 2 2 2 Macro domain Trp_oprn_chp PF09534.10 CDJ64634.1 - 0.0076 16.1 1.9 0.0076 16.1 1.9 2.8 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CENP-L PF13092.6 CDJ64634.1 - 0.052 13.8 0.2 0.052 13.8 0.2 3.0 4 0 0 4 4 4 0 Kinetochore complex Sim4 subunit Fta1 DUF2828 PF11443.8 CDJ64634.1 - 5.1 5.1 13.8 0.45 8.6 5.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF2877 PF11392.8 CDJ64634.1 - 9.1 7.0 0.0 9.1 7.0 0.0 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2877) CHZ PF09649.10 CDJ64635.1 - 0.05 13.1 0.2 0.24 10.9 0.2 2.3 1 0 0 1 1 1 0 Histone chaperone domain CHZ DUF775 PF05603.12 CDJ64636.1 - 2.4e-16 59.9 0.5 2.6e-12 46.7 0.5 3.4 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Secretin_N_2 PF07655.13 CDJ64636.1 - 0.099 13.2 15.3 0.14 12.7 15.3 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Herpes_capsid PF06112.11 CDJ64636.1 - 0.36 10.9 13.2 0.56 10.3 13.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Macoilin PF09726.9 CDJ64636.1 - 0.36 9.3 3.3 0.4 9.2 3.3 1.1 1 0 0 1 1 1 0 Macoilin family CCDC24 PF15669.5 CDJ64636.1 - 0.62 9.9 2.7 0.82 9.5 2.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family BT1 PF03092.16 CDJ64638.1 - 0.12 10.6 0.6 0.17 10.1 0.6 1.1 1 0 0 1 1 1 0 BT1 family V_ATPase_I PF01496.19 CDJ64638.1 - 0.67 7.8 7.7 0.81 7.5 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4446 PF14584.6 CDJ64638.1 - 1.8 8.6 4.9 2.7 8.0 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) OATP PF03137.20 CDJ64638.1 - 2.2 6.5 13.9 0.68 8.1 3.0 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Collagen PF01391.18 CDJ64640.1 - 3.9e-14 52.2 75.2 5.9e-08 32.4 32.7 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF2722 PF10846.8 CDJ64640.1 - 0.0024 16.9 10.5 0.0024 16.9 10.5 2.6 3 0 0 3 3 2 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ64640.1 - 0.0039 17.2 8.3 0.0039 17.2 8.3 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ64640.1 - 0.025 14.2 23.8 0.035 13.7 17.3 2.3 2 0 0 2 2 2 0 Spt20 family DUF3504 PF12012.8 CDJ64640.1 - 0.032 14.1 0.5 0.058 13.3 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) SLC12 PF03522.15 CDJ64640.1 - 0.054 12.5 1.5 0.086 11.9 1.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF4630 PF15443.6 CDJ64640.1 - 0.094 12.9 4.2 0.22 11.7 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) DUF1645 PF07816.11 CDJ64640.1 - 1.3 9.5 40.6 0.14 12.7 3.9 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1645) Macoilin PF09726.9 CDJ64640.1 - 1.9 6.9 20.2 0.58 8.6 10.2 2.2 2 0 0 2 2 2 0 Macoilin family EPL1 PF10513.9 CDJ64640.1 - 2.8 8.3 7.7 2.6 8.4 4.5 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Presenilin PF01080.17 CDJ64640.1 - 6.9 5.3 10.3 0.87 8.3 5.3 1.8 2 0 0 2 2 2 0 Presenilin RskA PF10099.9 CDJ64641.1 - 0.0013 19.0 6.3 0.0014 19.0 6.3 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ64641.1 - 0.0047 17.5 5.6 0.0073 16.9 5.6 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ64641.1 - 0.2 11.6 9.5 0.21 11.5 9.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 CDJ64641.1 - 1 8.5 11.4 1 8.5 11.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA PF00004.29 CDJ64642.1 - 1.2e-45 155.2 0.3 2.9e-34 118.4 0.0 3.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ64642.1 - 2.4e-07 30.5 0.0 7.9e-07 28.8 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ64642.1 - 2.3e-06 27.6 0.3 0.074 13.0 0.1 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TsaE PF02367.17 CDJ64642.1 - 0.00025 21.1 0.3 0.43 10.6 0.1 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 CDJ64642.1 - 0.0004 20.8 0.3 0.012 16.0 0.1 8.1 4 1 0 5 5 2 2 AAA ATPase domain RuvB_N PF05496.12 CDJ64642.1 - 0.00052 19.8 0.1 0.42 10.3 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CDJ64642.1 - 0.00082 19.7 0.5 1.5 9.3 0.0 3.9 3 0 0 3 3 2 1 RNA helicase TIP49 PF06068.13 CDJ64642.1 - 0.00087 18.6 0.0 0.14 11.4 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CDJ64642.1 - 0.0018 17.7 8.3 0.031 13.7 0.1 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 CDJ64642.1 - 0.0041 17.1 0.1 8.8 6.2 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CDJ64642.1 - 0.0048 16.7 3.3 0.37 10.5 0.0 3.7 3 0 0 3 3 3 1 IstB-like ATP binding protein CDC48_N PF02359.18 CDJ64642.1 - 0.0099 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_25 PF13481.6 CDJ64642.1 - 0.012 15.2 5.8 0.38 10.3 0.0 4.3 3 1 0 4 4 4 0 AAA domain AAA_22 PF13401.6 CDJ64642.1 - 0.016 15.5 0.1 0.016 15.5 0.1 6.3 6 2 0 6 6 2 0 AAA domain AAA_14 PF13173.6 CDJ64642.1 - 0.018 15.1 0.0 2.4 8.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CDJ64642.1 - 0.1 11.9 0.2 0.41 9.9 0.1 2.1 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.6 CDJ64642.1 - 0.19 11.5 0.4 5 6.9 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CDJ64642.1 - 0.26 11.0 0.0 0.26 11.0 0.0 4.5 5 0 0 5 5 3 0 AAA domain AAA_18 PF13238.6 CDJ64642.1 - 1.2 9.7 0.0 1.2 9.7 0.0 4.4 5 0 0 5 5 3 0 AAA domain TFIIA PF03153.13 CDJ64644.1 - 0.14 12.1 34.8 0.16 12.0 34.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2681 PF10883.8 CDJ64644.1 - 0.25 11.8 17.7 2.9 8.4 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Plasmodium_Vir PF05795.11 CDJ64644.1 - 0.31 10.4 13.5 0.39 10.1 13.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.12 CDJ64644.1 - 0.31 9.9 12.5 0.38 9.7 12.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ64644.1 - 0.57 9.2 14.1 0.77 8.7 14.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Cwf_Cwc_15 PF04889.12 CDJ64644.1 - 0.96 9.1 17.9 1.9 8.2 17.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GREB1 PF15782.5 CDJ64644.1 - 1 6.4 25.7 1 6.4 25.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDJ64644.1 - 2 6.9 34.5 3.1 6.2 34.5 1.3 1 0 0 1 1 1 0 Macoilin family DUF572 PF04502.13 CDJ64644.1 - 2.3 7.8 20.3 2.9 7.4 20.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SPX PF03105.19 CDJ64644.1 - 3.5 7.4 39.0 5.4 6.8 39.0 1.2 1 0 0 1 1 1 0 SPX domain XRN_M PF17846.1 CDJ64644.1 - 9.7 5.0 7.6 14 4.5 7.6 1.4 1 0 0 1 1 1 0 Xrn1 helical domain RskA PF10099.9 CDJ64645.1 - 0.0064 16.8 1.3 0.0064 16.8 1.3 19.7 6 6 8 14 14 14 3 Anti-sigma-K factor rskA Mito_carr PF00153.27 CDJ64646.1 - 1.9e-35 120.7 5.1 1.4e-15 56.9 0.0 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein RskA PF10099.9 CDJ64646.1 - 0.24 11.7 0.0 0.24 11.7 0.0 3.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Secretin_N_2 PF07655.13 CDJ64646.1 - 0.29 11.7 24.6 0.048 14.2 3.0 3.2 3 0 0 3 3 3 0 Secretin N-terminal domain BMP2K_C PF15282.6 CDJ64647.1 - 0.019 14.8 1.3 0.019 14.8 1.3 2.0 2 0 0 2 2 2 0 BMP-2-inducible protein kinase C-terminus SR-25 PF10500.9 CDJ64647.1 - 0.023 14.3 4.8 0.047 13.3 4.8 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EBP50_C PF09007.11 CDJ64647.1 - 1.4 9.9 7.4 2.4 9.2 1.8 2.4 2 0 0 2 2 2 0 EBP50, C-terminal TT_ORF1 PF02956.14 CDJ64648.1 - 3.6 6.2 5.5 4.9 5.7 5.5 1.1 1 0 0 1 1 1 0 TT viral orf 1 MORN PF02493.20 CDJ64649.1 - 3.8e-39 130.3 45.0 2.8e-06 26.9 1.0 7.2 7 0 0 7 7 7 7 MORN repeat DUF2722 PF10846.8 CDJ64651.1 - 0.44 9.4 6.6 0.73 8.7 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ64651.1 - 0.77 9.3 12.1 1.3 8.5 12.1 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ64651.1 - 1.7 8.6 11.2 0.13 12.2 5.3 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ64652.1 - 0.9 9.1 30.1 0.61 9.7 0.5 2.4 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4407 PF14362.6 CDJ64652.1 - 2.4 7.4 30.3 3.2 7.0 30.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SUIM_assoc PF16619.5 CDJ64653.1 - 0.00018 21.5 15.9 0.067 13.3 15.9 2.6 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 CRAL_TRIO_2 PF13716.6 CDJ64653.1 - 0.0013 18.9 0.0 0.0015 18.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PEX11 PF05648.14 CDJ64653.1 - 0.0073 15.8 4.1 0.011 15.2 4.1 1.3 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Presenilin PF01080.17 CDJ64653.1 - 0.047 12.5 0.4 0.036 12.8 0.4 1.1 1 0 0 1 1 1 0 Presenilin Herpes_glycop PF01528.16 CDJ64653.1 - 0.084 11.7 0.1 0.089 11.6 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF4834 PF16118.5 CDJ64653.1 - 0.23 12.4 5.5 0.35 11.9 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Porph_ging PF09697.10 CDJ64653.1 - 0.51 10.9 5.9 0.85 10.2 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) Spt20 PF12090.8 CDJ64653.1 - 0.89 9.1 23.4 1.2 8.7 23.4 1.2 1 0 0 1 1 1 0 Spt20 family Nucleoside_tran PF01733.18 CDJ64653.1 - 0.92 8.8 2.5 1.2 8.4 2.5 1.2 1 0 0 1 1 1 0 Nucleoside transporter TMEM208_SND2 PF05620.11 CDJ64653.1 - 1.7 8.4 6.4 2.1 8.1 6.4 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF1180 PF06679.12 CDJ64654.1 - 9.9 6.5 12.2 17 5.8 12.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) zf-B_box PF00643.24 CDJ64655.1 - 0.00012 22.2 7.6 0.00012 22.2 7.6 3.6 3 1 1 4 4 4 2 B-box zinc finger zf-C3HC4_3 PF13920.6 CDJ64655.1 - 0.012 15.4 17.0 0.012 15.4 17.0 3.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SseB_C PF14581.6 CDJ64655.1 - 0.031 14.4 0.3 7.3 6.7 0.1 2.9 2 1 1 3 3 3 0 SseB protein C-terminal domain FA_desaturase PF00487.24 CDJ64656.1 - 1.7e-19 70.6 21.4 3.6e-19 69.6 21.4 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 CDJ64656.1 - 3.4e-09 36.0 0.5 8.3e-09 34.8 0.0 1.9 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) RskA PF10099.9 CDJ64656.1 - 0.12 12.7 20.3 0.089 13.1 12.4 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF4820 PF16091.5 CDJ64656.1 - 0.26 10.6 6.5 0.24 10.8 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Spt20 PF12090.8 CDJ64656.1 - 0.29 10.7 25.0 1 8.9 5.2 2.2 2 0 0 2 2 2 0 Spt20 family ANAPC_CDC26 PF10471.9 CDJ64656.1 - 0.96 10.3 23.5 0.76 10.7 1.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 TFIIA PF03153.13 CDJ64656.1 - 2.2 8.2 27.0 0.45 10.5 8.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HNOBA PF07701.14 CDJ64656.1 - 5.1 6.5 7.3 0.93 8.9 2.9 1.8 2 0 0 2 2 2 0 Heme NO binding associated Mito_fiss_reg PF05308.11 CDJ64656.1 - 7 6.6 12.8 2.8 8.0 6.2 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator SUIM_assoc PF16619.5 CDJ64656.1 - 8.4 6.5 31.3 9.4 6.4 11.0 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 WRNPLPNID PF15017.6 CDJ64656.1 - 9.9 7.1 15.2 6.7 7.7 5.8 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Form-deh_trans PF09163.11 CDJ64657.1 - 0.0032 17.2 0.4 0.0069 16.1 0.4 1.5 1 0 0 1 1 1 1 Formate dehydrogenase N, transmembrane AAA_23 PF13476.6 CDJ64658.1 - 1.8 9.1 27.3 0.7 10.4 9.5 2.2 2 0 0 2 2 2 0 AAA domain DUF5523 PF17661.1 CDJ64658.1 - 2.9 7.5 30.6 4.8 6.8 15.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5523) PBP1_TM PF14812.6 CDJ64658.1 - 3.1 8.2 10.2 9.4 6.7 1.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S49_N PF08496.10 CDJ64658.1 - 3.3 7.8 22.8 1.7 8.7 7.5 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF2407_C PF13373.6 CDJ64658.1 - 5.9 7.1 16.8 0.13 12.4 2.2 2.6 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF4578 PF15147.6 CDJ64659.1 - 0.0018 19.2 1.3 0.002 19.0 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4578) DUF2722 PF10846.8 CDJ64659.1 - 0.0031 16.5 5.3 0.0033 16.4 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Duffy_binding PF05424.11 CDJ64659.1 - 0.0044 17.1 0.7 0.0052 16.9 0.7 1.1 1 0 0 1 1 1 1 Duffy binding domain RskA PF10099.9 CDJ64659.1 - 0.008 16.5 5.9 0.01 16.1 5.9 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA PEX11 PF05648.14 CDJ64659.1 - 0.029 13.8 0.6 0.032 13.7 0.6 1.0 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Spt20 PF12090.8 CDJ64659.1 - 0.047 13.3 11.5 0.052 13.2 11.5 1.1 1 0 0 1 1 1 0 Spt20 family TMEM51 PF15345.6 CDJ64659.1 - 0.054 13.3 1.6 0.061 13.2 1.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 ETRAMP PF09716.10 CDJ64659.1 - 0.075 13.1 0.0 0.095 12.8 0.0 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Calpain_inhib PF00748.19 CDJ64659.1 - 0.077 13.5 2.8 0.077 13.5 2.8 1.1 1 0 0 1 1 1 0 Calpain inhibitor RAB3GAP2_N PF14655.6 CDJ64659.1 - 0.1 11.8 1.7 0.1 11.8 1.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus OATP PF03137.20 CDJ64659.1 - 0.17 10.1 1.1 0.19 10.0 1.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Roughex PF06020.11 CDJ64659.1 - 0.28 10.3 5.3 0.3 10.2 5.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein UPF0560 PF10577.9 CDJ64659.1 - 0.3 9.5 5.1 0.35 9.3 5.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PHD_3 PF13922.6 CDJ64659.1 - 0.7 10.3 6.4 1 9.8 6.4 1.3 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx TSA PF03249.13 CDJ64659.1 - 0.71 8.6 6.0 0.7 8.6 6.0 1.1 1 0 0 1 1 1 0 Type specific antigen Med3 PF11593.8 CDJ64659.1 - 4 6.5 16.6 4.8 6.3 16.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SLC12 PF03522.15 CDJ64660.1 - 0.0075 15.3 13.4 0.0094 15.0 13.4 1.1 1 0 0 1 1 1 1 Solute carrier family 12 CPSF100_C PF13299.6 CDJ64660.1 - 0.019 15.2 9.3 0.078 13.2 1.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Otopetrin PF03189.13 CDJ64660.1 - 0.044 12.6 15.7 0.062 12.1 15.7 1.2 1 0 0 1 1 1 0 Otopetrin DUF4746 PF15928.5 CDJ64660.1 - 0.051 13.0 7.1 0.2 11.1 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CAF1 PF04857.20 CDJ64660.1 - 0.092 11.9 9.0 0.12 11.5 9.0 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Spt20 PF12090.8 CDJ64660.1 - 0.1 12.2 53.1 0.05 13.2 13.2 2.2 2 0 0 2 2 2 0 Spt20 family EPL1 PF10513.9 CDJ64660.1 - 0.27 11.6 19.0 0.25 11.7 7.1 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like RskA PF10099.9 CDJ64660.1 - 0.31 11.3 7.9 4.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Pex14_N PF04695.13 CDJ64660.1 - 0.42 11.3 28.8 1.5 9.4 14.9 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AUX_IAA PF02309.16 CDJ64660.1 - 0.54 10.1 10.7 0.78 9.5 10.7 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF1980 PF09323.10 CDJ64660.1 - 0.54 10.1 9.5 3 7.7 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Calpain_inhib PF00748.19 CDJ64660.1 - 1.1 9.8 12.4 4.3 7.8 6.4 2.1 2 0 0 2 2 2 0 Calpain inhibitor Peptidase_U57 PF05582.12 CDJ64660.1 - 1.4 8.1 10.6 0.87 8.8 3.3 2.0 2 0 0 2 2 2 0 YabG peptidase U57 DcuA_DcuB PF03605.14 CDJ64660.1 - 1.8 7.4 4.1 3.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter DUF4770 PF15994.5 CDJ64660.1 - 2.2 8.5 21.3 2 8.6 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Pal1 PF08316.11 CDJ64660.1 - 2.3 9.0 8.5 3 8.6 2.2 2.1 2 0 0 2 2 2 0 Pal1 cell morphology protein SpoIIP PF07454.11 CDJ64660.1 - 2.4 7.5 19.3 0.76 9.2 6.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Pex26 PF07163.12 CDJ64660.1 - 2.8 7.2 20.5 3 7.1 9.5 2.1 2 0 0 2 2 2 0 Pex26 protein Pinin_SDK_memA PF04696.13 CDJ64660.1 - 3.2 7.8 35.5 1 9.4 8.0 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF3807 PF12720.7 CDJ64660.1 - 4.1 7.6 27.2 4.8 7.4 13.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF5308 PF17233.2 CDJ64660.1 - 4.9 7.4 17.2 1.9 8.7 7.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5308) V_ATPase_I PF01496.19 CDJ64660.1 - 5 4.9 16.3 4.1 5.2 1.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PH_4 PF15404.6 CDJ64660.1 - 5.3 6.8 14.4 1.3 8.8 0.8 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Baculo_PP31 PF05311.11 CDJ64660.1 - 5.7 6.4 17.5 5.4 6.4 8.9 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Peptidase_S15 PF02129.18 CDJ64660.1 - 5.9 6.4 13.4 9.2 5.8 6.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) BAT2_N PF07001.11 CDJ64660.1 - 7.2 7.0 23.8 10 6.5 3.3 2.2 2 0 0 2 2 2 0 BAT2 N-terminus Folate_carrier PF01770.18 CDJ64660.1 - 7.6 5.2 11.5 4.5 5.9 3.5 2.1 2 0 0 2 2 2 0 Reduced folate carrier CagX PF03524.15 CDJ64660.1 - 7.6 6.2 11.1 3.1 7.5 0.7 2.2 2 0 0 2 2 2 0 Conjugal transfer protein DUF4638 PF15472.6 CDJ64660.1 - 8.2 6.1 17.6 7.8 6.1 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) AIF_C PF14721.6 CDJ64660.1 - 8.6 6.7 17.8 2.3 8.6 0.6 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ALMT PF11744.8 CDJ64660.1 - 9.2 5.0 14.2 13 4.4 8.2 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter RPA43_OB PF17875.1 CDJ64660.1 - 9.9 6.8 13.1 5.7 7.6 1.2 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Pkinase PF00069.25 CDJ64661.1 - 6.5e-24 84.7 0.1 7.3e-24 84.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ64661.1 - 5.5e-14 52.1 0.1 6.4e-14 51.9 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RPE65 PF03055.15 CDJ64661.1 - 0.056 12.6 0.0 0.057 12.6 0.0 1.0 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein His_binding PF02098.16 CDJ64661.1 - 0.056 13.5 0.0 0.074 13.1 0.0 1.2 1 0 0 1 1 1 0 Tick histamine binding protein DUF2722 PF10846.8 CDJ64662.1 - 5e-05 22.4 5.4 5e-05 22.4 5.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ64662.1 - 0.00024 21.2 16.2 0.00024 21.2 16.2 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 CDJ64662.1 - 0.0011 19.0 6.6 0.0015 18.5 6.6 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term MMR1 PF08505.10 CDJ64662.1 - 0.036 14.4 9.7 0.056 13.7 9.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DivIC PF04977.15 CDJ64662.1 - 0.12 12.2 6.9 0.34 10.7 6.9 1.8 1 0 0 1 1 1 0 Septum formation initiator eIF-3_zeta PF05091.12 CDJ64662.1 - 0.17 10.8 9.3 0.23 10.4 9.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2572 PF10833.8 CDJ64662.1 - 0.53 10.0 5.4 0.83 9.4 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) DUF1754 PF08555.10 CDJ64662.1 - 0.62 10.9 11.7 1.5 9.6 11.7 1.6 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) RR_TM4-6 PF06459.12 CDJ64662.1 - 0.87 9.4 6.9 1.5 8.6 6.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ64662.1 - 0.93 9.5 5.9 1.6 8.7 5.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PIP5K PF01504.18 CDJ64662.1 - 0.94 8.6 4.5 1.4 8.1 4.5 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Band_3_cyto PF07565.13 CDJ64662.1 - 1.6 8.4 8.4 4.3 7.1 8.4 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain WBP-1 PF11669.8 CDJ64662.1 - 1.7 9.3 6.8 0.15 12.7 1.8 1.9 2 0 0 2 2 1 0 WW domain-binding protein 1 Spore_coat_CotO PF14153.6 CDJ64662.1 - 3 7.8 13.7 6 6.7 13.7 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Gti1_Pac2 PF09729.9 CDJ64662.1 - 3 7.9 8.8 5.8 7.0 8.8 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4834 PF16118.5 CDJ64662.1 - 3.2 8.8 15.8 22 6.1 9.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ64662.1 - 3.4 7.6 13.9 6 6.8 13.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Roughex PF06020.11 CDJ64662.1 - 5.5 6.0 9.0 8.3 5.4 9.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Hid1 PF12722.7 CDJ64662.1 - 7.6 4.5 8.9 10 4.1 8.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TMEM51 PF15345.6 CDJ64664.1 - 0.013 15.3 1.8 0.026 14.4 1.8 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 NTP_transf_5 PF14907.6 CDJ64664.1 - 0.18 11.4 11.3 0.2 11.2 1.8 2.2 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase DUF1631 PF07793.11 CDJ64664.1 - 0.22 9.9 28.4 0.28 9.5 28.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF4834 PF16118.5 CDJ64664.1 - 0.31 12.0 3.2 0.68 10.9 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Baculo_PP31 PF05311.11 CDJ64664.1 - 0.92 8.9 7.2 0.36 10.3 1.7 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Spt20 PF12090.8 CDJ64664.1 - 1.3 8.5 20.4 0.019 14.6 13.0 1.6 2 0 0 2 2 2 0 Spt20 family Ndc1_Nup PF09531.10 CDJ64664.1 - 1.7 7.2 12.3 2 7.0 12.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Roughex PF06020.11 CDJ64664.1 - 2.7 7.0 7.1 4.8 6.2 7.1 1.5 1 0 0 1 1 1 0 Drosophila roughex protein HTH_32 PF13565.6 CDJ64664.1 - 3.2 8.5 7.3 0.52 11.0 2.1 2.3 2 1 0 2 2 2 0 Homeodomain-like domain V_ATPase_I PF01496.19 CDJ64664.1 - 4.8 5.0 7.2 2.1 6.2 2.8 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CDK2AP PF09806.9 CDJ64664.1 - 7.1 6.6 28.3 98 2.9 28.3 2.0 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Na_sulph_symp PF00939.19 CDJ64665.1 - 1.3e-29 103.5 11.9 1.8e-14 53.6 7.6 2.1 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CDJ64665.1 - 1.5e-17 63.8 53.8 1.4e-08 34.3 4.2 3.4 2 1 1 3 3 3 3 Citrate transporter DUF4834 PF16118.5 CDJ64665.1 - 0.37 11.8 0.1 0.37 11.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ64665.1 - 2 7.9 16.5 0.11 12.2 9.6 2.0 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ64665.1 - 6.7 5.5 15.4 0.093 11.7 7.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) FAM76 PF16046.5 CDJ64666.1 - 1.2 8.4 5.8 1.7 7.9 5.8 1.2 1 0 0 1 1 1 0 FAM76 protein Pkinase PF00069.25 CDJ64667.1 - 5.9e-65 219.3 0.0 7.4e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ64667.1 - 2.1e-29 102.6 0.0 2.6e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ64667.1 - 4.8e-06 26.1 0.0 1.9e-05 24.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ64667.1 - 0.00014 21.3 0.5 0.00039 19.8 0.5 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ64667.1 - 0.00017 20.5 0.1 0.00041 19.3 0.1 1.6 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ64667.1 - 0.0067 16.4 0.0 0.42 10.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RNase_HII PF01351.18 CDJ64668.1 - 1.5e-50 171.8 0.0 3.5e-46 157.6 0.1 2.2 2 0 0 2 2 2 2 Ribonuclease HII Aminotran_4 PF01063.19 CDJ64669.1 - 1.1e-12 48.4 0.3 2.4e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Amino-transferase class IV EIIBC-GUT_N PF03612.14 CDJ64669.1 - 0.15 11.8 1.3 0.91 9.2 2.2 1.7 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Connexin PF00029.19 CDJ64669.1 - 0.99 9.1 3.1 1.8 8.3 3.1 1.4 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ64669.1 - 2.9 6.6 9.1 5.4 5.7 9.1 1.3 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ64669.1 - 3.2 8.8 8.9 0.6 11.1 4.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Zip PF02535.22 CDJ64669.1 - 3.9 6.6 5.0 6.6 5.8 4.4 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter PhoLip_ATPase_N PF16209.5 CDJ64672.1 - 6.4e-16 57.8 0.5 1.8e-15 56.4 0.1 1.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CDJ64672.1 - 6.8e-08 32.2 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Vps55 PF04133.14 CDJ64672.1 - 0.093 12.7 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 55 Guanylate_cyc PF00211.20 CDJ64673.1 - 1e-81 272.9 0.8 2.1e-43 148.1 0.2 2.6 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 CDJ64673.1 - 2.8e-53 181.2 21.7 2.8e-53 181.2 21.7 4.5 4 1 1 5 5 5 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 CDJ64673.1 - 5.4e-07 30.1 0.0 0.021 15.1 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ64673.1 - 1.2e-05 25.8 0.1 0.011 16.2 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ64673.1 - 2.4e-05 24.2 0.0 0.00053 19.8 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1053 PF06327.14 CDJ64673.1 - 0.17 12.4 0.9 8.2 7.0 0.2 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) Abhydrolase_9_N PF15420.6 CDJ64673.1 - 0.61 10.0 8.7 0.19 11.7 0.8 2.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Amidase PF01425.21 CDJ64674.1 - 2.8e-05 23.3 0.5 0.013 14.5 0.1 2.9 3 0 0 3 3 3 2 Amidase DUF1298 PF06974.13 CDJ64674.1 - 0.023 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) SAC3_GANP PF03399.16 CDJ64675.1 - 4.1e-29 101.9 0.0 4.1e-29 101.9 0.0 3.4 4 1 0 4 4 4 1 SAC3/GANP family DUF2938 PF11158.8 CDJ64676.1 - 0.0046 16.4 1.3 0.008 15.7 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2938) TauE PF01925.19 CDJ64677.1 - 1.9e-23 83.3 22.6 3.8e-11 43.1 0.1 2.1 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF4328 PF14219.6 CDJ64677.1 - 0.0073 15.9 0.2 0.021 14.4 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) Presenilin PF01080.17 CDJ64677.1 - 0.49 9.1 5.4 1 8.1 5.4 1.5 1 0 0 1 1 1 0 Presenilin IHABP4_N PF16174.5 CDJ64678.1 - 0.019 15.6 2.1 0.019 15.6 2.1 3.5 2 1 1 3 3 3 0 Intracellular hyaluronan-binding protein 4 N-terminal Citrate_synt PF00285.21 CDJ64679.1 - 6.2e-70 236.1 0.0 4.5e-34 118.1 0.0 2.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain WD40 PF00400.32 CDJ64680.1 - 1.2e-44 149.3 30.7 1.6e-09 38.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ64680.1 - 3.2e-11 43.4 2.7 0.082 13.2 0.0 4.9 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDJ64680.1 - 1.1e-07 31.5 0.0 0.00016 21.1 0.0 2.6 2 1 1 3 3 3 3 WD40-like domain PQQ_3 PF13570.6 CDJ64680.1 - 0.00048 20.5 0.9 0.079 13.5 0.0 3.7 3 1 0 3 3 3 1 PQQ-like domain Nup160 PF11715.8 CDJ64680.1 - 0.0051 15.5 17.1 0.09 11.4 0.3 5.0 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Adeno_terminal PF02459.15 CDJ64680.1 - 0.081 11.3 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein tRNA-synt_1 PF00133.22 CDJ64681.1 - 1.6e-77 261.2 0.0 3.6e-38 131.2 0.0 5.4 5 1 0 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDJ64681.1 - 8.5e-09 34.6 1.2 1e-05 24.5 0.0 3.8 4 0 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CDJ64681.1 - 0.046 13.2 0.2 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 Presenilin PF01080.17 CDJ64681.1 - 3.3 6.4 4.7 7.8 5.1 0.3 2.3 2 0 0 2 2 2 0 Presenilin DUF2012 PF09430.10 CDJ64682.1 - 3.5e-10 40.0 0.0 5.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) OTU PF02338.19 CDJ64683.1 - 1.5e-09 38.4 0.0 4e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDJ64683.1 - 6.1e-05 22.6 0.0 0.0062 16.0 0.1 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain VWA PF00092.28 CDJ64684.1 - 1.5e-34 119.8 0.0 2e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 CDJ64684.1 - 5.3e-26 90.6 65.9 1.4e-07 31.6 2.3 7.1 6 0 0 6 6 6 6 Thrombospondin type 1 domain VWA_2 PF13519.6 CDJ64684.1 - 5.5e-16 59.2 0.0 1e-15 58.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 CDJ64684.1 - 0.019 15.1 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus Pro_isomerase PF00160.21 CDJ64685.1 - 1.7e-35 122.6 0.0 1.7e-35 122.6 0.0 2.6 3 0 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF5470 PF17564.2 CDJ64685.1 - 0.00027 21.1 1.0 0.00027 21.1 1.0 7.4 4 1 1 5 5 5 1 Family of unknown function (DUF5470) Spt20 PF12090.8 CDJ64685.1 - 0.0027 17.3 13.2 0.0027 17.3 13.2 7.4 7 0 0 7 7 7 5 Spt20 family AAA_23 PF13476.6 CDJ64685.1 - 0.83 10.1 59.3 0.34 11.4 1.1 6.0 6 0 0 6 6 6 0 AAA domain EPL1 PF10513.9 CDJ64685.1 - 1 9.7 0.0 1 9.7 0.0 7.7 6 2 0 6 6 6 0 Enhancer of polycomb-like RNA_pol_Rpb1_2 PF00623.20 CDJ64687.1 - 0.13 12.4 3.6 0.49 10.6 3.6 2.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 GGDEF_2 PF17853.1 CDJ64688.1 - 0.036 14.3 4.2 5.7 7.2 0.3 3.5 1 1 2 3 3 3 0 GGDEF-like domain DUF3446 PF11928.8 CDJ64688.1 - 0.061 13.6 57.2 0.29 11.5 6.8 5.3 5 0 0 5 5 5 0 Early growth response N-terminal domain Foie-gras_1 PF11817.8 CDJ64688.1 - 1.1 8.8 6.2 0.091 12.3 0.6 2.0 3 0 0 3 3 3 0 Foie gras liver health family 1 IMUP PF15761.5 CDJ64688.1 - 4 8.2 59.4 0.92 10.2 7.4 5.3 5 0 0 5 5 5 0 Immortalisation up-regulated protein Kinesin PF00225.23 CDJ64689.1 - 1.9e-60 204.6 10.6 1.9e-60 204.6 10.6 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ64689.1 - 3.6e-12 46.5 5.7 3.6e-12 46.5 5.7 3.5 3 1 0 3 3 3 1 Microtubule binding BT1 PF03092.16 CDJ64689.1 - 0.11 10.7 0.9 0.29 9.3 0.9 1.7 1 0 0 1 1 1 0 BT1 family DUF2722 PF10846.8 CDJ64690.1 - 6.7e-06 25.3 6.6 8.1e-06 25.0 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) SseC PF04888.12 CDJ64690.1 - 0.00052 19.7 9.1 0.00052 19.7 9.1 3.1 3 0 0 3 3 2 1 Secretion system effector C (SseC) like family EPL1 PF10513.9 CDJ64690.1 - 0.016 15.6 1.0 0.029 14.7 1.0 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like Roughex PF06020.11 CDJ64690.1 - 0.12 11.5 9.2 0.22 10.6 9.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Rrn6 PF10214.9 CDJ64690.1 - 0.24 9.9 9.7 0.33 9.4 9.7 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Neur_chan_memb PF02932.16 CDJ64690.1 - 0.26 11.3 1.3 0.4 10.7 1.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 CDJ64690.1 - 0.5 9.9 29.0 0.021 14.4 23.0 1.6 2 0 0 2 2 2 0 Spt20 family DUF4820 PF16091.5 CDJ64690.1 - 0.55 9.5 8.9 1.5 8.2 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) UPF0560 PF10577.9 CDJ64690.1 - 4.7 5.6 14.8 7.1 5.0 14.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TERB2 PF15101.6 CDJ64690.1 - 7.4 6.6 14.3 0.19 11.8 8.0 1.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 eIF-3_zeta PF05091.12 CDJ64690.1 - 9.1 5.1 11.3 14 4.5 11.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RskA PF10099.9 CDJ64691.1 - 0.0013 19.0 10.9 0.0013 19.0 10.9 2.2 1 1 1 2 2 2 1 Anti-sigma-K factor rskA SLC12 PF03522.15 CDJ64691.1 - 0.079 12.0 21.5 0.1 11.6 21.5 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Utp14 PF04615.13 CDJ64691.1 - 0.77 8.3 28.2 0.96 7.9 28.2 1.0 1 0 0 1 1 1 0 Utp14 protein PAT1 PF09770.9 CDJ64691.1 - 1.2 7.3 57.3 1.4 7.1 57.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIF_alpha PF05793.12 CDJ64691.1 - 1.3 7.5 17.5 1.7 7.1 17.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.9 CDJ64691.1 - 1.7 7.1 38.2 2.5 6.6 38.2 1.2 1 1 0 1 1 1 0 Macoilin family CDC45 PF02724.14 CDJ64691.1 - 3.4 5.8 21.9 4.2 5.6 21.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RIFIN PF02009.16 CDJ64691.1 - 3.7 7.3 16.3 4.8 7.0 16.3 1.3 1 0 0 1 1 1 0 Rifin SPX PF03105.19 CDJ64691.1 - 3.9 7.3 33.4 5.2 6.9 33.4 1.3 1 0 0 1 1 1 0 SPX domain GREB1 PF15782.5 CDJ64691.1 - 4.2 4.4 35.4 4.8 4.2 35.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Membralin PF09746.9 CDJ64691.1 - 4.7 6.2 11.7 6.2 5.8 11.7 1.3 1 0 0 1 1 1 0 Tumour-associated protein Miff PF05644.11 CDJ64691.1 - 6.2 6.4 28.0 9.7 5.7 28.0 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Asp-B-Hydro_N PF05279.11 CDJ64691.1 - 8.4 6.4 17.3 10 6.1 17.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Apt1 PF10351.9 CDJ64692.1 - 0.069 12.0 7.8 0.075 11.9 7.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ64692.1 - 0.19 11.6 9.5 0.23 11.4 9.5 1.1 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 CDJ64692.1 - 0.28 10.8 31.5 1.1 8.8 12.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1117 PF06547.12 CDJ64692.1 - 0.61 10.7 8.1 0.97 10.0 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) Macoilin PF09726.9 CDJ64692.1 - 1.9 6.9 10.6 2.8 6.4 10.6 1.3 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 CDJ64692.1 - 2 8.3 6.7 2.6 7.9 6.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GREB1 PF15782.5 CDJ64692.1 - 6.7 3.7 10.7 7.7 3.5 10.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LSM PF01423.22 CDJ64693.1 - 4.4e-15 55.1 0.3 5.2e-15 54.9 0.3 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDJ64693.1 - 0.001 19.2 0.2 0.0028 17.8 0.2 1.6 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF2642 PF10842.8 CDJ64693.1 - 0.038 13.9 0.1 0.095 12.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2642) Dapper PF15268.6 CDJ64694.1 - 0.0085 15.0 23.2 0.011 14.6 23.2 1.1 1 0 0 1 1 1 1 Dapper Bacillus_HBL PF05791.11 CDJ64694.1 - 0.021 14.7 26.8 0.041 13.7 26.8 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) BAF1_ABF1 PF04684.13 CDJ64694.1 - 0.027 13.6 12.6 0.035 13.2 12.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF812 PF05667.11 CDJ64694.1 - 0.028 13.3 27.3 0.054 12.4 27.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Herpes_VP19C PF03327.14 CDJ64694.1 - 0.1 12.1 2.9 0.73 9.2 2.9 2.1 1 1 0 1 1 1 0 Herpesvirus capsid shell protein VP19C DFP PF04127.15 CDJ64694.1 - 0.22 11.4 8.0 0.38 10.6 8.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Dehydrin PF00257.19 CDJ64694.1 - 0.24 11.9 0.2 0.24 11.9 0.2 2.6 2 1 1 3 3 3 0 Dehydrin Peptidase_S64 PF08192.11 CDJ64694.1 - 0.25 9.8 13.8 0.39 9.2 13.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Spc7 PF08317.11 CDJ64694.1 - 0.4 9.5 37.8 0.27 10.1 33.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Med15 PF09606.10 CDJ64694.1 - 0.56 8.8 52.0 0.81 8.3 52.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Exonuc_VII_L PF02601.15 CDJ64694.1 - 0.61 9.6 36.0 0.029 14.0 29.5 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 CDJ64694.1 - 0.83 7.5 20.3 1.3 6.9 20.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RAG1_imp_bd PF12560.8 CDJ64694.1 - 1.3 8.5 10.6 2.7 7.5 10.6 1.5 1 0 0 1 1 1 0 RAG1 importin binding DUF3584 PF12128.8 CDJ64694.1 - 1.4 6.3 39.3 2.3 5.6 39.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PAT1 PF09770.9 CDJ64694.1 - 2.4 6.3 33.4 3.4 5.8 33.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF722 PF05263.11 CDJ64694.1 - 2.7 8.2 9.6 1.2 9.4 5.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF722) Senescence_reg PF04520.13 CDJ64694.1 - 4 8.2 11.8 2.2 9.1 8.5 2.0 2 0 0 2 2 2 0 Senescence regulator DUF5320 PF17253.2 CDJ64694.1 - 4.2 8.5 25.5 1.1 10.3 7.4 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5320) LMBR1 PF04791.16 CDJ64694.1 - 5.5 5.8 16.1 8 5.2 16.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DNA_topoisoIV PF00521.20 CDJ64694.1 - 7.2 5.4 17.4 12 4.7 17.4 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF4208 PF13907.6 CDJ64694.1 - 8.2 6.9 14.8 2.5 8.6 8.7 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4208) DUF444 PF04285.12 CDJ64695.1 - 0.0007 18.8 2.3 0.00078 18.6 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF444) TFIIA PF03153.13 CDJ64695.1 - 0.0038 17.3 25.6 0.0038 17.3 25.6 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ64695.1 - 0.0088 16.1 11.9 0.0088 16.1 11.9 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) CPSF100_C PF13299.6 CDJ64695.1 - 0.015 15.5 5.2 0.014 15.6 5.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RskA PF10099.9 CDJ64695.1 - 0.02 15.2 17.5 0.027 14.8 17.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA eIF-3_zeta PF05091.12 CDJ64695.1 - 0.038 13.0 8.0 0.036 13.1 8.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SprA-related PF12118.8 CDJ64695.1 - 0.058 12.5 21.0 0.07 12.3 21.0 1.1 1 0 0 1 1 1 0 SprA-related family DUF4820 PF16091.5 CDJ64695.1 - 0.074 12.4 5.1 0.088 12.2 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Helicase_RecD PF05127.14 CDJ64695.1 - 0.077 12.8 3.4 0.093 12.6 3.4 1.1 1 0 0 1 1 1 0 Helicase SpoIIP PF07454.11 CDJ64695.1 - 0.1 12.1 8.1 0.1 12.0 8.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CTU2 PF10288.9 CDJ64695.1 - 0.11 12.7 6.0 0.13 12.5 6.0 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Pex14_N PF04695.13 CDJ64695.1 - 0.12 13.1 20.9 0.13 12.9 20.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FHIPEP PF00771.20 CDJ64695.1 - 0.16 10.4 5.4 0.18 10.3 5.4 1.0 1 0 0 1 1 1 0 FHIPEP family DDHD PF02862.17 CDJ64695.1 - 0.18 12.0 6.0 0.16 12.1 6.0 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 CDJ64695.1 - 0.18 11.6 7.0 0.17 11.7 7.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3824 PF12868.7 CDJ64695.1 - 0.18 12.4 16.9 0.57 10.8 16.9 1.8 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) GBP_C PF02841.14 CDJ64695.1 - 0.19 11.1 14.2 0.23 10.9 14.2 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Spt20 PF12090.8 CDJ64695.1 - 0.19 11.3 30.9 0.22 11.1 30.9 1.1 1 0 0 1 1 1 0 Spt20 family CCDC53 PF10152.9 CDJ64695.1 - 0.2 12.1 10.9 0.23 11.9 10.9 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RNase_H2_suC PF08615.11 CDJ64695.1 - 0.2 11.8 5.2 0.33 11.1 5.2 1.4 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) AIF_C PF14721.6 CDJ64695.1 - 0.23 11.8 6.5 0.28 11.5 6.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EOS1 PF12326.8 CDJ64695.1 - 0.29 11.0 1.8 0.3 11.0 1.8 1.1 1 0 0 1 1 1 0 N-glycosylation protein Connexin PF00029.19 CDJ64695.1 - 0.32 10.7 3.5 0.37 10.5 3.5 1.1 1 0 0 1 1 1 0 Connexin IHABP4_N PF16174.5 CDJ64695.1 - 0.36 11.4 16.9 0.52 10.9 16.9 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Neur_chan_memb PF02932.16 CDJ64695.1 - 0.36 10.8 4.4 0.36 10.9 4.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF5521 PF17659.1 CDJ64695.1 - 0.4 8.5 6.9 0.43 8.4 6.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DUF3682 PF12446.8 CDJ64695.1 - 0.46 11.0 24.1 0.67 10.4 24.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF3464 PF11947.8 CDJ64695.1 - 0.49 10.1 7.5 0.57 9.9 7.5 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FAM60A PF15396.6 CDJ64695.1 - 0.55 10.2 5.2 0.62 10.0 5.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Serinc PF03348.15 CDJ64695.1 - 0.66 8.8 3.8 0.68 8.8 3.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hid1 PF12722.7 CDJ64695.1 - 0.71 7.9 5.9 0.71 7.9 5.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CDJ64695.1 - 0.73 8.5 11.6 0.83 8.4 11.6 1.0 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ64695.1 - 0.92 6.5 8.9 0.93 6.5 8.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RAB3GAP2_N PF14655.6 CDJ64695.1 - 0.98 8.6 7.5 1.2 8.3 7.5 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Rxt3 PF08642.10 CDJ64695.1 - 1 10.1 4.9 1.3 9.8 4.9 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 TERB2 PF15101.6 CDJ64695.1 - 1.2 9.2 12.7 1.3 9.0 12.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2722 PF10846.8 CDJ64695.1 - 1.3 7.9 29.4 1.7 7.5 29.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Tim54 PF11711.8 CDJ64695.1 - 1.3 7.8 10.6 1.4 7.6 10.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 UPF0560 PF10577.9 CDJ64695.1 - 1.3 7.4 14.6 1.3 7.4 14.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4834 PF16118.5 CDJ64695.1 - 1.4 10.0 11.5 2.2 9.3 11.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3450 PF11932.8 CDJ64695.1 - 1.5 8.1 20.9 1.7 7.9 20.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Coilin_N PF15862.5 CDJ64695.1 - 1.5 8.7 12.4 1.9 8.3 12.4 1.1 1 0 0 1 1 1 0 Coilin N-terminus V_ATPase_I PF01496.19 CDJ64695.1 - 1.5 6.6 7.3 1.7 6.5 7.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 CDJ64695.1 - 1.7 7.9 15.5 1.9 7.8 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PP31 PF05311.11 CDJ64695.1 - 1.8 8.0 8.7 2.1 7.8 8.7 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FYDLN_acid PF09538.10 CDJ64695.1 - 2.1 9.1 7.9 2.9 8.6 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) R_equi_Vir PF05526.11 CDJ64695.1 - 2.2 8.1 9.0 2.8 7.8 9.0 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Plasmodium_Vir PF05795.11 CDJ64695.1 - 2.6 7.4 5.7 2.6 7.4 5.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1980 PF09323.10 CDJ64695.1 - 2.7 7.9 5.3 3.1 7.7 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) OATP PF03137.20 CDJ64695.1 - 4.2 5.6 4.2 4.4 5.5 4.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4770 PF15994.5 CDJ64695.1 - 4.3 7.5 14.0 5.2 7.3 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF2391 PF09622.10 CDJ64695.1 - 5.2 6.3 5.8 6.6 6.0 5.8 1.1 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) PAT1 PF09770.9 CDJ64695.1 - 6.1 5.0 21.3 7.1 4.8 21.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 CDJ64695.1 - 6.2 6.5 9.4 7.3 6.3 9.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ndc1_Nup PF09531.10 CDJ64695.1 - 6.6 5.3 10.4 6.8 5.2 10.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Orf78 PF06024.12 CDJ64695.1 - 6.7 7.1 6.8 9 6.7 6.8 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Ctr PF04145.15 CDJ64695.1 - 7.8 7.1 5.7 9.2 6.9 5.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family CLN3 PF02487.17 CDJ64695.1 - 8.2 5.4 6.7 8.9 5.2 6.7 1.0 1 0 0 1 1 1 0 CLN3 protein EIIBC-GUT_N PF03612.14 CDJ64695.1 - 8.4 6.1 11.0 10 5.8 11.0 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Herpes_DNAp_acc PF04929.12 CDJ64695.1 - 9.2 5.1 12.3 10 5.0 12.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor ANAPC4_WD40 PF12894.7 CDJ64696.1 - 1.3e-06 28.6 0.1 0.0043 17.3 0.0 3.7 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ64696.1 - 0.00011 22.9 17.9 0.64 11.0 0.1 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CDJ64696.1 - 0.0086 15.1 0.7 0.062 12.3 0.0 2.1 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CDJ64696.1 - 0.035 13.4 0.8 0.82 8.9 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CDJ64696.1 - 0.058 12.0 0.0 1.1 7.9 0.0 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 CDJ64696.1 - 5.6 6.1 11.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus MRP-S31 PF15433.6 CDJ64696.1 - 5.9 6.5 12.3 10 5.7 12.3 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 SR-25 PF10500.9 CDJ64696.1 - 9.3 5.8 15.8 0.92 9.1 10.6 1.9 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Hydrolase_4 PF12146.8 CDJ64698.1 - 1.7e-09 37.3 10.2 9.9e-09 34.8 0.2 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DUF913 PF06025.12 CDJ64698.1 - 0.0047 16.0 1.4 0.0065 15.5 1.4 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF2052 PF09747.9 CDJ64698.1 - 0.0048 17.1 4.2 0.0087 16.2 4.2 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) MBR1 PF17058.5 CDJ64698.1 - 0.043 14.1 4.4 0.071 13.4 4.4 1.2 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 Neur_chan_memb PF02932.16 CDJ64698.1 - 0.045 13.8 2.8 0.066 13.3 2.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 CDJ64698.1 - 0.14 10.8 14.1 0.21 10.2 14.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ64698.1 - 0.16 10.7 10.9 0.25 10.1 10.9 1.2 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 CDJ64698.1 - 0.46 9.3 5.9 0.79 8.6 5.9 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MCU PF04678.13 CDJ64698.1 - 0.59 10.2 3.8 1.4 9.0 3.8 1.7 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4834 PF16118.5 CDJ64698.1 - 0.77 10.8 15.3 9.2 7.3 9.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) VIR_N PF15912.5 CDJ64698.1 - 1 8.9 9.9 1.6 8.2 9.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal eIF-3_zeta PF05091.12 CDJ64698.1 - 1.5 7.7 12.0 2.9 6.8 12.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF908 PF06012.12 CDJ64698.1 - 1.6 8.0 10.7 2.4 7.5 10.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) FlaG PF03646.15 CDJ64698.1 - 1.7 8.9 24.2 0.9 9.7 14.6 2.3 2 0 0 2 2 2 0 FlaG protein RR_TM4-6 PF06459.12 CDJ64698.1 - 4 7.2 10.7 18 5.1 11.4 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.9 CDJ64698.1 - 4.6 7.3 7.7 9.5 6.3 7.7 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4484 PF14831.6 CDJ64698.1 - 6.7 6.7 10.7 12 5.9 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF5521 PF17659.1 CDJ64699.1 - 0.15 9.9 1.3 0.17 9.7 1.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) TFIIA PF03153.13 CDJ64699.1 - 1.5 8.7 13.2 1.9 8.4 13.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NINJA_B PF16136.5 CDJ64699.1 - 3.9 7.9 11.3 0.086 13.2 4.6 1.8 2 0 0 2 2 2 0 Putative nuclear localisation signal Spt20 PF12090.8 CDJ64699.1 - 6.4 6.3 11.3 8.9 5.8 11.3 1.1 1 0 0 1 1 1 0 Spt20 family GTA_holin_3TM PF11351.8 CDJ64700.1 - 0.35 11.4 3.6 0.65 10.6 3.6 1.3 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release YebO PF13974.6 CDJ64700.1 - 7.5 6.7 11.2 14 5.9 11.2 1.4 1 0 0 1 1 1 0 YebO-like protein Dehydrin PF00257.19 CDJ64701.1 - 0.0037 17.8 11.3 0.0037 17.8 11.3 3.4 1 1 1 2 2 2 1 Dehydrin SR-25 PF10500.9 CDJ64701.1 - 0.68 9.5 60.5 0.15 11.7 27.8 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Plasmodium_Vir PF05795.11 CDJ64701.1 - 0.94 8.8 12.4 1.1 8.6 12.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RIFIN PF02009.16 CDJ64701.1 - 4.3 7.1 24.8 5.4 6.8 24.1 1.4 1 1 0 1 1 1 0 Rifin DUF812 PF05667.11 CDJ64702.1 - 0.23 10.3 3.5 0.29 10.0 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Ndc1_Nup PF09531.10 CDJ64702.1 - 0.56 8.8 4.2 0.65 8.6 4.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Med13_C PF06333.12 CDJ64702.1 - 0.56 9.4 7.3 0.88 8.8 7.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain GREB1 PF15782.5 CDJ64702.1 - 4.8 4.2 7.3 5.9 3.9 7.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NifU PF01106.17 CDJ64703.1 - 0.00045 20.3 0.0 0.0008 19.5 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Ribosomal_L19e PF01280.20 CDJ64704.1 - 6.2e-16 58.8 3.0 6.2e-16 58.8 3.0 2.1 1 1 1 2 2 2 1 Ribosomal protein L19e YhzD PF14120.6 CDJ64704.1 - 0.46 10.6 3.3 1.2 9.3 3.3 1.7 1 0 0 1 1 1 0 YhzD-like protein Cgr1 PF03879.14 CDJ64704.1 - 0.58 10.5 20.3 0.086 13.2 16.3 1.6 1 1 1 2 2 2 0 Cgr1 family BRE1 PF08647.11 CDJ64704.1 - 3.8 7.6 17.2 3.2 7.9 10.0 2.5 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase PP2C PF00481.21 CDJ64707.1 - 6.1e-10 39.2 0.1 7e-07 29.1 0.0 2.7 2 1 1 3 3 3 2 Protein phosphatase 2C Spt20 PF12090.8 CDJ64707.1 - 0.61 9.6 14.1 0.95 9.0 14.1 1.3 1 0 0 1 1 1 0 Spt20 family DUF2339 PF10101.9 CDJ64708.1 - 1.8e-08 33.5 1.2 1.8e-08 33.5 1.2 3.3 3 0 0 3 3 3 2 Predicted membrane protein (DUF2339) TFIIA PF03153.13 CDJ64708.1 - 4.4e-05 23.7 23.4 4.4e-05 23.7 23.4 6.1 2 1 2 4 4 4 1 Transcription factor IIA, alpha/beta subunit Proteasome PF00227.26 CDJ64709.1 - 1.4e-57 194.3 0.0 1.6e-39 135.4 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 CDJ64709.1 - 9e-10 38.0 0.9 2e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Spt20 PF12090.8 CDJ64709.1 - 0.0062 16.2 3.7 0.0083 15.8 3.7 1.2 1 0 0 1 1 1 1 Spt20 family SUIM_assoc PF16619.5 CDJ64709.1 - 0.012 15.7 5.5 0.022 14.8 5.5 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ64709.1 - 0.027 13.4 1.7 0.031 13.2 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SAPIS-gp6 PF16722.5 CDJ64709.1 - 3.1 8.3 8.0 31 5.1 8.5 2.2 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus DEAD PF00270.29 CDJ64710.1 - 9.2e-21 74.4 0.0 1.2e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 CDJ64710.1 - 0.00033 20.1 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Helicase_C PF00271.31 CDJ64711.1 - 3.6e-27 94.9 0.1 5.7e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TerD PF02342.18 CDJ64713.1 - 2.3e-05 24.0 0.0 4.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 TerD domain CCDC24 PF15669.5 CDJ64713.1 - 2.8 7.8 12.5 8 6.3 12.0 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Ribosomal_60s PF00428.19 CDJ64714.1 - 0.0054 17.3 7.8 0.018 15.6 7.8 2.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein CRAL_TRIO PF00650.20 CDJ64714.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 CRAL/TRIO domain YbgS PF13985.6 CDJ64714.1 - 2.2 8.6 7.6 6.1 7.2 5.5 2.2 2 0 0 2 2 2 0 YbgS-like protein SNF2_N PF00176.23 CDJ64717.1 - 6.3e-64 215.9 1.0 6.3e-64 215.9 1.0 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ64717.1 - 2.6e-19 69.6 0.0 2.6e-19 69.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_25 PF13481.6 CDJ64717.1 - 0.064 12.8 0.0 0.33 10.5 0.0 2.3 1 0 0 1 1 1 0 AAA domain IP_trans PF02121.18 CDJ64718.1 - 1.5e-60 204.9 0.0 4.2e-41 141.2 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol transfer protein Oxysterol_BP PF01237.18 CDJ64718.1 - 2.7e-13 49.5 0.0 5.6e-12 45.2 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 CDJ64718.1 - 4.1e-11 43.3 0.0 7.8e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CDJ64718.1 - 0.059 13.8 0.2 1.8 9.1 0.2 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain YbhQ PF11076.8 CDJ64718.1 - 0.065 13.3 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ Kinesin PF00225.23 CDJ64719.1 - 2.1e-86 289.9 0.0 3.6e-86 289.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ64719.1 - 5.8e-18 65.3 0.0 1.5e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding AIP3 PF03915.13 CDJ64719.1 - 0.0014 17.8 0.6 0.0014 17.8 0.6 1.5 2 0 0 2 2 2 1 Actin interacting protein 3 PH_17 PF18012.1 CDJ64719.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 PH domain Hs1pro-1_C PF07014.12 CDJ64719.1 - 0.053 13.0 0.0 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Hs1pro-1 protein C-terminus AAA_22 PF13401.6 CDJ64719.1 - 0.15 12.4 2.7 22 5.3 0.2 3.1 3 0 0 3 3 3 0 AAA domain PK PF00224.21 CDJ64721.1 - 1.5e-77 260.9 0.0 4.7e-37 127.7 0.8 3.1 3 0 0 3 3 3 3 Pyruvate kinase, barrel domain PK_C PF02887.16 CDJ64721.1 - 2.6e-13 50.2 0.0 1.7e-12 47.6 0.0 2.3 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain adh_short_C2 PF13561.6 CDJ64722.1 - 2.9e-63 213.6 4.7 3.5e-63 213.3 4.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ64722.1 - 1.3e-57 194.4 2.4 1.6e-57 194.1 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDJ64722.1 - 6.1e-21 75.1 0.4 1e-20 74.4 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDJ64722.1 - 0.00064 19.3 0.4 0.0014 18.2 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 CDJ64722.1 - 0.012 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Seadorna_Vp10 PF07322.11 CDJ64722.1 - 0.051 13.0 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus Vp10 Eno-Rase_NADH_b PF12242.8 CDJ64722.1 - 0.13 12.0 3.4 0.18 11.6 1.2 2.1 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2205 PF10224.9 CDJ64723.1 - 0.00015 21.6 3.2 0.00015 21.6 3.2 3.4 1 1 1 2 2 1 1 Short coiled-coil protein FlaC_arch PF05377.11 CDJ64723.1 - 0.0023 18.3 1.7 0.0023 18.3 1.7 2.0 2 1 0 2 2 1 1 Flagella accessory protein C (FlaC) HOOK PF05622.12 CDJ64723.1 - 0.0074 14.5 29.1 0.0094 14.2 29.1 1.1 1 0 0 1 1 1 1 HOOK protein TFIIA PF03153.13 CDJ64723.1 - 0.03 14.4 40.2 0.033 14.2 40.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cnn_1N PF07989.11 CDJ64723.1 - 0.035 14.3 1.7 0.035 14.3 1.7 3.1 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 AAA_11 PF13086.6 CDJ64723.1 - 0.1 12.4 16.4 0.13 12.0 16.4 1.2 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 CDJ64723.1 - 0.99 8.1 21.9 1.2 7.8 21.9 1.3 1 0 0 1 1 1 0 Presenilin Tam41_Mmp37 PF09139.11 CDJ64723.1 - 1.1 8.6 10.3 1.4 8.3 10.3 1.2 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial GREB1 PF15782.5 CDJ64723.1 - 1.6 5.7 22.2 1.8 5.6 22.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FapA PF03961.13 CDJ64723.1 - 1.6 7.2 14.4 2.2 6.8 14.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF935 PF06074.12 CDJ64723.1 - 3.3 6.4 21.6 4.1 6.0 21.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DUF3584 PF12128.8 CDJ64723.1 - 4 4.8 35.7 5 4.5 35.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PAT1 PF09770.9 CDJ64723.1 - 4.8 5.3 34.1 5.3 5.2 34.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ64723.1 - 5.5 6.7 21.1 7 6.4 21.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YabA PF06156.13 CDJ64723.1 - 6.4 7.5 25.7 8.8e+02 0.6 25.4 2.3 1 1 0 1 1 1 0 Initiation control protein YabA MRP-S27 PF10037.9 CDJ64723.1 - 7.3 5.3 22.3 9.7 4.9 22.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Lin-8 PF03353.15 CDJ64723.1 - 8.8 5.8 22.1 11 5.5 22.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ALMT PF11744.8 CDJ64723.1 - 8.9 5.0 19.3 11 4.7 19.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 CDJ64723.1 - 9.3 6.2 14.8 12 5.9 14.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NEMP PF10225.9 CDJ64724.1 - 1.8 8.2 3.4 4.1 7.0 3.4 1.5 1 0 0 1 1 1 0 NEMP family RINGv PF12906.7 CDJ64725.1 - 1e-12 47.9 4.4 2.1e-12 47.0 4.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 CDJ64725.1 - 0.21 11.9 4.4 0.47 10.8 4.4 1.7 1 0 0 1 1 1 0 Ring finger domain RVT_1 PF00078.27 CDJ64726.1 - 4.9e-06 26.2 0.0 9.2e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ64727.1 - 2.7e-28 97.9 0.0 3.8e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ64727.1 - 1.6e-27 95.8 0.1 2.1e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 CDJ64728.1 - 1.1e-12 47.6 0.6 1.7e-12 47.1 0.1 1.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CDJ64729.1 - 1.2e-11 44.8 0.0 1.9e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 CDJ64730.1 - 8.4e-13 48.6 0.0 1.1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain SecM PF06558.12 CDJ64730.1 - 0.12 12.5 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) RVP_2 PF08284.11 CDJ64731.1 - 3.5e-09 36.5 0.0 5.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ64731.1 - 1.6e-08 35.0 0.0 2.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ64731.1 - 5.2e-08 33.4 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ64731.1 - 0.18 12.1 0.0 0.76 10.1 0.0 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 CDJ64732.1 - 1.4e-08 34.4 14.0 1.3e-06 28.2 2.8 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ64732.1 - 0.02 14.7 1.5 0.02 14.7 1.5 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ64732.1 - 0.021 14.7 2.2 0.021 14.7 2.2 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ64732.1 - 0.13 12.0 7.7 0.43 10.4 1.6 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ64732.1 - 0.64 9.8 11.1 3.1 7.6 2.7 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 CDJ64732.1 - 1.4 9.0 12.4 0.085 12.8 2.6 2.7 1 1 1 2 2 2 0 Zinc knuckle Choline_transpo PF04515.12 CDJ64733.1 - 6.1e-19 68.4 1.0 6.1e-19 68.4 1.0 2.6 2 1 1 3 3 3 1 Plasma-membrane choline transporter MotB_plug PF13677.6 CDJ64733.1 - 0.93 9.1 6.6 9.9 5.8 0.0 3.1 3 0 0 3 3 3 0 Membrane MotB of proton-channel complex MotA/MotB RskA PF10099.9 CDJ64734.1 - 0.0059 16.9 17.7 0.0059 16.9 17.7 3.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Phostensin_N PF13916.6 CDJ64734.1 - 2.9 8.3 17.0 2 8.8 0.6 3.9 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal SUIM_assoc PF16619.5 CDJ64734.1 - 8.7 6.5 46.5 0.063 13.3 7.0 4.2 2 2 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PP2C_2 PF13672.6 CDJ64737.1 - 5.1 6.7 8.3 0.078 12.6 1.1 1.6 2 0 0 2 2 2 0 Protein phosphatase 2C V-SNARE_C PF12352.8 CDJ64738.1 - 0.0011 19.2 1.0 0.0025 18.1 1.0 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus LSM PF01423.22 CDJ64739.1 - 2.2e-16 59.3 0.0 2.6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain RskA PF10099.9 CDJ64740.1 - 0.0022 18.3 9.9 0.0022 18.3 9.9 11.1 2 2 4 6 6 6 2 Anti-sigma-K factor rskA zf-C2HC5 PF06221.13 CDJ64740.1 - 0.086 12.8 7.8 2.2 8.3 7.8 3.0 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DEAD PF00270.29 CDJ64741.1 - 2.3e-09 37.2 3.1 4.5e-09 36.3 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ64741.1 - 3.9e-09 36.8 0.0 4.4e-07 30.2 0.1 3.7 3 1 0 3 3 3 1 Helicase conserved C-terminal domain SR-25 PF10500.9 CDJ64741.1 - 0.00011 21.9 7.1 0.00011 21.9 7.1 4.5 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ64741.1 - 0.0023 17.0 1.2 0.0023 17.0 1.2 5.5 4 1 1 5 5 5 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ64741.1 - 0.0078 15.9 7.9 0.0078 15.9 7.9 5.6 5 1 1 6 6 6 3 Spt20 family TFIIA PF03153.13 CDJ64741.1 - 0.014 15.4 102.6 0.24 11.4 8.3 4.6 4 0 0 4 4 4 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ64741.1 - 0.016 14.3 0.4 0.016 14.3 0.4 4.1 4 0 0 4 4 4 0 BAF1 / ABF1 chromatin reorganising factor DDHD PF02862.17 CDJ64741.1 - 4.4 7.4 38.4 0.17 12.0 1.6 4.5 4 1 0 4 4 4 0 DDHD domain Exonuc_VII_L PF02601.15 CDJ64742.1 - 0.017 14.7 11.8 0.038 13.6 11.8 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 CDJ64742.1 - 0.021 13.4 6.1 0.029 13.0 6.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Vitellogenin_N PF01347.22 CDJ64742.1 - 0.49 8.7 18.2 0.43 8.9 16.9 1.5 2 0 0 2 2 2 0 Lipoprotein amino terminal region LMBR1 PF04791.16 CDJ64742.1 - 4.2 6.2 5.6 5.6 5.7 5.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PAT1 PF09770.9 CDJ64742.1 - 7.4 4.7 29.2 10 4.3 29.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RMMBL PF07521.12 CDJ64743.1 - 1e-13 51.0 0.1 2.4e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Cpn60_TCP1 PF00118.24 CDJ64745.1 - 1e-80 271.8 0.5 2.8e-80 270.3 0.5 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family GP3_package PF16677.5 CDJ64745.1 - 0.08 13.1 0.5 4.9 7.3 0.1 2.5 2 0 0 2 2 2 0 DNA-packaging protein gp3 Nbl1_Borealin_N PF10444.9 CDJ64745.1 - 0.37 10.5 2.1 0.38 10.4 0.2 2.0 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal DNA_primase_lrg PF04104.14 CDJ64745.1 - 0.72 9.2 2.0 4.9 6.5 0.2 2.1 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit GBP PF02263.19 CDJ64747.1 - 3.1e-18 66.0 0.0 1.6e-13 50.6 0.0 2.6 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 CDJ64747.1 - 2.2e-12 47.0 19.0 3.4e-12 46.4 19.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain LMBR1 PF04791.16 CDJ64747.1 - 6.7 5.5 9.0 12 4.7 9.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein MFS_1 PF07690.16 CDJ64748.1 - 1.1e-10 41.0 20.8 2.9e-10 39.6 20.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily ERGIC_N PF13850.6 CDJ64748.1 - 0.52 10.7 4.1 0.33 11.3 0.4 2.5 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TRAPPC-Trs85 PF12739.7 CDJ64749.1 - 2.7e-80 270.3 0.0 1.2e-79 268.2 0.0 1.9 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.6 CDJ64749.1 - 0.014 14.8 0.3 0.074 12.5 0.0 2.1 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Presenilin PF01080.17 CDJ64749.1 - 1 8.0 13.9 0.15 10.8 1.8 2.4 2 0 0 2 2 2 0 Presenilin DUF842 PF05811.13 CDJ64750.1 - 1.2e-28 99.4 11.4 1.4e-28 99.2 11.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) TBCC_N PF16752.5 CDJ64750.1 - 0.68 10.4 4.2 3.9 7.9 0.2 2.9 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Rubis-subs-bind PF09273.11 CDJ64751.1 - 0.032 14.9 0.0 0.093 13.4 0.0 1.7 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding SUIM_assoc PF16619.5 CDJ64751.1 - 0.047 13.8 1.0 0.11 12.5 1.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SET PF00856.28 CDJ64751.1 - 0.14 12.6 0.0 3.6 7.9 0.0 2.6 2 1 0 2 2 2 0 SET domain Asp PF00026.23 CDJ64753.1 - 2.1e-65 221.3 0.0 2.6e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ64753.1 - 4.3e-07 30.3 5.3 9.5e-06 26.0 0.2 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal ATP-synt_E PF05680.12 CDJ64753.1 - 0.062 13.7 1.0 0.11 12.8 1.0 1.4 1 0 0 1 1 1 0 ATP synthase E chain M_domain PF12938.7 CDJ64753.1 - 0.19 11.5 15.2 2.2 8.0 0.2 2.2 2 0 0 2 2 2 0 M domain of GW182 Phage_r1t_holin PF16945.5 CDJ64753.1 - 0.43 10.8 3.4 0.91 9.8 3.4 1.4 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin SUIM_assoc PF16619.5 CDJ64753.1 - 0.77 9.9 8.5 1.6 8.8 8.5 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ64753.1 - 4.3 6.9 6.3 7.3 6.1 6.3 1.3 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.10 CDJ64754.1 - 0.93 8.1 47.6 1.4 7.5 47.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PRELI PF04707.14 CDJ64755.1 - 9.3e-34 116.5 0.0 1.5e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 PRELI-like family Shisa PF13908.6 CDJ64755.1 - 0.0026 18.0 0.9 0.0026 18.0 0.9 3.1 4 0 0 4 4 4 1 Wnt and FGF inhibitory regulator Peptidase_C54 PF03416.19 CDJ64755.1 - 0.006 16.0 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family C54 SelK_SelG PF10961.8 CDJ64755.1 - 8.7 7.0 9.4 9.1 7.0 1.6 2.5 2 0 0 2 2 2 0 Selenoprotein SelK_SelG MFS_1 PF07690.16 CDJ64757.1 - 2.5e-10 39.8 12.5 3.1e-10 39.5 12.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2722 PF10846.8 CDJ64757.1 - 0.0073 15.3 2.3 0.0087 15.1 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ64757.1 - 0.011 15.7 1.9 0.013 15.6 1.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sugar_tr PF00083.24 CDJ64757.1 - 0.025 13.5 1.2 0.054 12.3 0.4 1.9 2 0 0 2 2 2 0 Sugar (and other) transporter TMEM208_SND2 PF05620.11 CDJ64757.1 - 0.06 13.1 0.3 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Spt20 PF12090.8 CDJ64757.1 - 0.16 11.6 11.3 0.22 11.1 11.3 1.1 1 0 0 1 1 1 0 Spt20 family EPL1 PF10513.9 CDJ64759.1 - 0.0062 16.9 3.1 0.0062 16.9 3.1 2.1 2 0 0 2 2 2 1 Enhancer of polycomb-like Cas_TM1802 PF09484.10 CDJ64759.1 - 0.015 14.1 2.6 0.022 13.5 2.6 1.2 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) Presenilin PF01080.17 CDJ64759.1 - 0.036 12.8 13.2 0.038 12.7 13.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4050 PF13259.6 CDJ64759.1 - 0.14 12.5 8.0 0.2 12.0 8.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF2828 PF11443.8 CDJ64759.1 - 0.31 9.1 11.0 0.36 8.9 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Sin_N PF04801.13 CDJ64759.1 - 0.65 9.1 21.6 0.87 8.7 21.6 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region SLC12 PF03522.15 CDJ64759.1 - 0.73 8.8 12.4 0.8 8.7 12.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Jak1_Phl PF17887.1 CDJ64759.1 - 0.95 9.4 9.6 1.5 8.8 9.6 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain SARAF PF06682.12 CDJ64759.1 - 1.3 8.6 14.3 1.8 8.1 14.3 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Atrophin-1 PF03154.15 CDJ64759.1 - 1.4 7.2 14.5 1.3 7.2 14.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family SpoIIP PF07454.11 CDJ64759.1 - 1.4 8.3 14.5 0.037 13.5 2.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2076 PF09849.9 CDJ64759.1 - 1.7 8.6 36.5 2.9 7.9 36.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PAT1 PF09770.9 CDJ64759.1 - 1.8 6.8 27.2 1.9 6.6 27.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Vfa1 PF08432.10 CDJ64759.1 - 1.8 8.8 23.0 3.6 7.9 23.0 1.5 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.16 CDJ64759.1 - 1.9 8.5 10.2 2.6 8.0 10.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ANAPC8 PF04049.13 CDJ64759.1 - 2.3 8.3 12.7 0.048 13.7 2.6 2.2 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 DUF778 PF05608.12 CDJ64759.1 - 8.6 6.7 7.7 10 6.4 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Sec62 PF03839.16 CDJ64759.1 - 9.9 5.6 10.2 0.65 9.5 2.4 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 TFIIA PF03153.13 CDJ64760.1 - 0.00045 20.3 25.8 0.076 13.0 20.5 2.5 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Ni_hydr_CYTB PF01292.20 CDJ64762.1 - 0.23 11.0 6.5 0.94 9.0 6.5 2.1 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Ribosomal_60s PF00428.19 CDJ64763.1 - 0.019 15.6 0.2 0.019 15.6 0.2 11.0 5 3 3 8 8 8 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ64763.1 - 0.42 10.2 57.9 0.13 11.9 22.8 3.5 3 0 0 3 3 3 0 Spt20 family DUF3138 PF11336.8 CDJ64765.1 - 0.78 8.3 4.2 1 7.9 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Dynein_attach_N PF15867.5 CDJ64765.1 - 2.4 8.2 7.0 1.3 9.0 1.5 2.3 1 1 1 2 2 2 0 Dynein attachment factor N-terminus pP_pnuc_2 PF18166.1 CDJ64766.1 - 9.3 6.4 7.8 20 5.3 0.6 2.9 1 1 1 2 2 2 0 Predicted pPIWI-associating nuclease MCM_lid PF17855.1 CDJ64767.1 - 1.8e-19 70.0 0.3 8.6e-19 67.8 0.0 2.1 1 1 1 2 2 2 1 MCM AAA-lid domain Androgen_recep PF02166.16 CDJ64767.1 - 0.92 8.3 5.4 1.3 7.7 5.4 1.2 1 0 0 1 1 1 0 Androgen receptor SUIM_assoc PF16619.5 CDJ64767.1 - 3.2 7.9 11.3 1.2 9.3 8.2 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AAA_lid_2 PF17863.1 CDJ64767.1 - 5.3 6.9 9.5 0.1 12.4 2.1 2.0 2 0 0 2 2 2 0 AAA lid domain TPR_4 PF07721.14 CDJ64767.1 - 8.3 7.4 9.8 1 10.2 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat eIF-3_zeta PF05091.12 CDJ64768.1 - 0.02 13.9 15.0 0.021 13.9 15.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF572 PF04502.13 CDJ64768.1 - 0.61 9.6 21.3 0.84 9.2 21.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MFAP1 PF06991.11 CDJ64768.1 - 2.5 7.9 25.7 0.037 13.9 2.1 2.1 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing FHIPEP PF00771.20 CDJ64768.1 - 3.2 6.1 11.7 0.75 8.2 8.7 1.5 1 1 1 2 2 2 0 FHIPEP family SR-25 PF10500.9 CDJ64768.1 - 5.7 6.5 34.4 41 3.7 34.5 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.9 CDJ64768.1 - 7.6 4.7 29.4 9.1 4.4 29.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2722 PF10846.8 CDJ64769.1 - 0.00012 21.2 0.0 0.00012 21.2 0.0 7.4 3 2 3 6 6 6 2 Protein of unknown function (DUF2722) Macoilin PF09726.9 CDJ64769.1 - 0.0044 15.7 12.5 0.0044 15.7 12.5 3.7 2 1 0 2 2 2 1 Macoilin family RskA PF10099.9 CDJ64769.1 - 0.0085 16.4 8.6 0.0085 16.4 8.6 5.5 2 1 2 4 4 4 2 Anti-sigma-K factor rskA Med15 PF09606.10 CDJ64771.1 - 0.00063 18.6 12.5 0.00064 18.6 12.5 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SUIM_assoc PF16619.5 CDJ64771.1 - 0.0037 17.3 5.9 0.0045 17.0 5.9 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF2065 PF09838.9 CDJ64771.1 - 0.059 13.4 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) Nfu_N PF08712.11 CDJ64771.1 - 0.2 11.7 0.0 0.26 11.3 0.0 1.1 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal Spt20 PF12090.8 CDJ64771.1 - 0.5 9.9 6.7 0.59 9.7 6.7 1.1 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ64771.1 - 3.5 6.7 8.4 4.4 6.4 8.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal BTB PF00651.31 CDJ64772.1 - 1.8e-10 41.0 0.0 1.6e-09 38.0 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain UPF0565 PF10561.9 CDJ64772.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Integrase_H2C2 PF17921.1 CDJ64773.1 - 1.2e-16 60.5 0.7 2.5e-16 59.5 0.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ64773.1 - 9.8e-06 25.7 0.3 2.3e-05 24.5 0.3 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Mvb12 PF09452.10 CDJ64773.1 - 0.12 12.8 0.1 1.9 9.0 0.0 2.3 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 rve PF00665.26 CDJ64774.1 - 0.053 13.7 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain RT_RNaseH_2 PF17919.1 CDJ64775.1 - 7.4e-29 99.7 0.0 1.5e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ64775.1 - 1.5e-23 83.0 0.0 3.8e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ64775.1 - 1.7e-18 66.9 0.0 3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CDJ64775.1 - 6.2e-09 35.7 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ64775.1 - 3.2e-08 34.1 0.0 7.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ64775.1 - 6.1e-08 33.1 0.0 1.4e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ64775.1 - 0.007 16.2 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ64775.1 - 0.0097 16.2 0.0 0.04 14.2 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease DUF3552 PF12072.8 CDJ64775.1 - 0.024 14.1 1.8 0.04 13.3 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Retrotrans_gag PF03732.17 CDJ64776.1 - 0.013 15.8 0.0 0.051 13.9 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein AIM5 PF17050.5 CDJ64776.1 - 0.14 13.0 0.8 0.19 12.5 0.0 1.7 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 DUF3446 PF11928.8 CDJ64778.1 - 0.0012 19.0 12.3 0.0012 19.0 12.3 2.0 2 1 0 2 2 2 1 Early growth response N-terminal domain PUF PF00806.19 CDJ64778.1 - 0.002 17.7 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 Pumilio-family RNA binding repeat AF-4 PF05110.13 CDJ64778.1 - 0.0026 16.0 5.2 0.0036 15.5 5.2 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein TPPK_C PF12555.8 CDJ64778.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.9 2 1 1 3 3 3 0 Thiamine pyrophosphokinase C terminal MID_MedPIWI PF18296.1 CDJ64778.1 - 1.7 8.3 7.0 3.7 7.3 7.0 1.5 1 1 0 1 1 1 0 MID domain of medPIWI SR-25 PF10500.9 CDJ64778.1 - 2.7 7.6 21.1 9 5.8 0.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1633 PF07794.11 CDJ64778.1 - 4.4 5.4 9.0 5.3 5.1 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) SR-25 PF10500.9 CDJ64779.1 - 0.0035 17.0 10.5 0.0035 17.0 10.5 7.5 2 2 5 7 7 7 2 Nuclear RNA-splicing-associated protein Med3 PF11593.8 CDJ64780.1 - 0.013 14.7 17.6 0.017 14.3 17.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GT87 PF09594.10 CDJ64780.1 - 0.019 14.7 4.0 0.77 9.4 0.1 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 87 TFIIA PF03153.13 CDJ64780.1 - 0.053 13.5 9.0 0.055 13.5 9.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tic110 PF16940.5 CDJ64780.1 - 0.34 9.3 6.8 0.35 9.3 6.8 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter FAM199X PF15814.5 CDJ64780.1 - 0.52 9.3 5.3 0.6 9.1 5.3 1.0 1 0 0 1 1 1 0 Protein family FAM199X Spt20 PF12090.8 CDJ64780.1 - 0.69 9.5 12.9 0.83 9.2 12.9 1.1 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ64780.1 - 1.5 9.1 27.3 4.8 7.4 27.3 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ64780.1 - 4.4 6.1 11.2 5.6 5.8 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Exo_endo_phos PF03372.23 CDJ64782.1 - 0.17 11.4 1.8 0.17 11.4 0.7 1.5 1 1 1 2 2 2 0 Endonuclease/Exonuclease/phosphatase family HC2 PF07382.11 CDJ64782.1 - 2.7 8.1 6.4 3.5 7.7 6.4 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 DUF4813 PF16072.5 CDJ64782.1 - 5.3 6.6 9.4 6.7 6.3 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) AP2 PF00847.20 CDJ64784.1 - 8.1e-09 35.6 7.5 8.1e-09 35.6 7.5 3.2 4 0 0 4 4 4 1 AP2 domain RskA PF10099.9 CDJ64784.1 - 0.0018 18.6 4.8 0.0018 18.6 4.8 8.4 3 2 2 5 5 5 1 Anti-sigma-K factor rskA Activator_LAG-3 PF11498.8 CDJ64784.1 - 1.5 7.7 13.7 4.9 6.0 6.7 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SUIM_assoc PF16619.5 CDJ64784.1 - 9.9 6.3 18.1 0.47 10.5 0.7 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 CDJ64787.1 - 6.2e-19 67.6 0.2 3.3e-15 55.6 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ64787.1 - 1.4e-07 31.5 0.0 0.0059 16.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif FHA PF00498.26 CDJ64788.1 - 6.2e-16 58.5 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ64788.1 - 3.7e-08 33.6 0.2 8.8e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Nbs1_C PF08599.10 CDJ64790.1 - 0.02 15.0 3.4 0.02 15.0 3.4 4.1 2 2 1 3 3 3 0 DNA damage repair protein Nbs1 DUF3824 PF12868.7 CDJ64790.1 - 0.28 11.9 0.1 0.28 11.9 0.1 3.1 2 1 1 3 3 3 0 Domain of unknwon function (DUF3824) DEAD_2 PF06733.15 CDJ64791.1 - 5e-15 55.6 12.7 2.6e-05 23.9 0.0 3.8 4 0 0 4 4 4 3 DEAD_2 ResIII PF04851.15 CDJ64791.1 - 0.00018 21.6 12.5 0.03 14.3 0.0 3.7 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit RskA PF10099.9 CDJ64791.1 - 0.0011 19.2 17.8 0.0011 19.2 17.8 7.5 3 3 2 5 5 5 2 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ64791.1 - 0.0041 16.8 16.7 0.0041 16.8 16.7 3.8 4 0 0 4 4 4 3 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ64791.1 - 0.017 15.4 19.3 0.017 15.4 19.3 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF755) DUF4389 PF14333.6 CDJ64791.1 - 0.28 11.1 2.6 0.83 9.6 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Apt1 PF10351.9 CDJ64791.1 - 0.67 8.8 28.1 0.054 12.3 4.5 3.3 3 0 0 3 3 3 0 Golgi-body localisation protein domain BAF1_ABF1 PF04684.13 CDJ64792.1 - 0.45 9.5 18.2 0.011 14.8 11.4 1.8 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor tRNA_lig_CPD PF08302.11 CDJ64792.1 - 3.5 7.0 12.6 2.2 7.7 6.4 2.2 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain DUF2722 PF10846.8 CDJ64793.1 - 0.0012 17.9 9.4 0.0012 17.9 9.4 7.6 7 3 2 9 9 9 2 Protein of unknown function (DUF2722) Abhydrolase_1 PF00561.20 CDJ64793.1 - 0.016 14.8 0.0 0.016 14.8 0.0 2.9 3 0 0 3 3 3 0 alpha/beta hydrolase fold Mito_carr PF00153.27 CDJ64797.1 - 2.1e-39 133.3 1.8 6.5e-19 67.7 0.3 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Asp PF00026.23 CDJ64798.1 - 1.7e-18 67.1 0.0 4e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease PUB PF09409.10 CDJ64799.1 - 7.1e-06 25.9 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 PUB domain CCDC53 PF10152.9 CDJ64799.1 - 0.019 15.4 1.0 0.019 15.4 1.0 1.8 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex EF-hand_1 PF00036.32 CDJ64800.1 - 1.3e-27 93.2 4.3 1.9e-07 30.1 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CDJ64800.1 - 1.7e-24 84.2 3.7 5.6e-07 28.8 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ64800.1 - 4.2e-24 84.8 2.3 2.8e-12 46.9 0.5 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ64800.1 - 1e-20 71.8 3.4 0.00094 18.9 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDJ64800.1 - 5.7e-13 48.5 7.0 3.7e-05 23.5 1.4 4.6 4 1 1 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ64800.1 - 1.2e-09 38.5 0.0 0.00023 21.4 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDJ64800.1 - 2.4e-05 24.2 1.9 0.19 11.7 0.3 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CDJ64800.1 - 0.00018 21.6 4.6 0.0086 16.2 0.1 3.8 2 1 2 4 4 4 3 Dockerin type I domain EF-hand_9 PF14658.6 CDJ64800.1 - 0.00079 19.7 0.0 0.048 14.0 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain NOD2_WH PF17779.1 CDJ64800.1 - 0.031 14.6 0.1 1.6 9.1 0.0 2.7 3 0 0 3 3 3 0 NOD2 winged helix domain Caleosin PF05042.13 CDJ64800.1 - 0.044 13.7 1.1 4.6 7.2 0.0 3.2 2 1 2 4 4 4 0 Caleosin related protein DUF2280 PF10045.9 CDJ64801.1 - 0.062 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) Glyco_transf_90 PF05686.12 CDJ64802.1 - 1.3e-65 221.9 0.0 2e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Thioredoxin PF00085.20 CDJ64802.1 - 1e-42 144.3 0.0 7.9e-21 74.0 0.0 3.5 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.6 CDJ64802.1 - 1.5e-09 38.3 0.0 0.0028 18.1 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDJ64802.1 - 1.5e-07 31.5 0.0 0.023 14.8 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 CDJ64802.1 - 6e-06 25.8 1.0 0.00059 19.3 0.0 3.4 4 0 0 4 4 4 1 OST3 / OST6 family, transporter family Glyco_trans_1_2 PF13524.6 CDJ64802.1 - 0.00017 21.9 0.0 0.00043 20.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Thioredoxin_6 PF13848.6 CDJ64802.1 - 0.00073 19.5 0.0 0.092 12.6 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Glutaredoxin PF00462.24 CDJ64802.1 - 0.00099 19.3 0.1 1.2 9.4 0.0 3.6 3 0 0 3 3 3 1 Glutaredoxin ERp29_N PF07912.13 CDJ64802.1 - 0.003 17.7 0.0 0.038 14.1 0.0 2.4 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_9 PF14595.6 CDJ64802.1 - 0.01 15.6 0.0 2.2 8.1 0.0 3.3 3 0 0 3 3 3 0 Thioredoxin Thioredoxin_8 PF13905.6 CDJ64802.1 - 0.013 15.9 0.1 12 6.3 0.0 3.7 3 1 1 4 4 4 0 Thioredoxin-like TraF PF13728.6 CDJ64802.1 - 0.014 15.2 0.0 3.4 7.4 0.0 2.8 2 1 1 3 3 3 0 F plasmid transfer operon protein RskA PF10099.9 CDJ64802.1 - 0.036 14.4 1.6 0.4 10.9 0.5 2.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA tRNA-synt_1g PF09334.11 CDJ64803.1 - 8e-38 130.2 0.0 1e-37 129.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CDJ64803.1 - 2.5e-10 39.3 0.1 1.8e-09 36.4 0.0 1.8 1 1 1 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CDJ64803.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 CDJ64803.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) RskA PF10099.9 CDJ64803.1 - 8 6.7 28.2 0.12 12.7 10.6 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA HRDC PF00570.23 CDJ64804.1 - 0.0097 15.9 0.5 0.018 15.0 0.5 1.4 1 0 0 1 1 1 1 HRDC domain DUF1800 PF08811.11 CDJ64804.1 - 0.21 10.6 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Lin-8 PF03353.15 CDJ64805.1 - 0.0054 16.3 15.8 0.0054 16.3 15.8 3.4 3 1 0 3 3 3 1 Ras-mediated vulval-induction antagonist Ribosomal_L18 PF17135.4 CDJ64806.1 - 1.8e-64 216.6 1.0 4.1e-64 215.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CDJ64806.1 - 0.016 15.9 0.0 0.032 14.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SUIM_assoc PF16619.5 CDJ64806.1 - 0.034 14.2 2.8 0.082 13.0 2.8 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Robl_LC7 PF03259.17 CDJ64806.1 - 3.7 7.4 9.4 0.4 10.5 2.2 2.3 2 0 0 2 2 2 0 Roadblock/LC7 domain Fibrillarin PF01269.17 CDJ64807.1 - 4.8e-76 254.8 0.0 5.4e-76 254.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CDJ64807.1 - 0.00014 21.7 0.0 0.00016 21.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DREV PF05219.12 CDJ64807.1 - 0.023 13.8 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltr_RsmB-F PF01189.17 CDJ64807.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F NUDIX-like PF09296.11 CDJ64807.1 - 0.14 12.8 0.0 2.9 8.6 0.0 2.2 1 1 1 2 2 2 0 NADH pyrophosphatase-like rudimentary NUDIX domain MDM1 PF15501.6 CDJ64808.1 - 7.1e-05 22.1 20.5 8.9e-05 21.8 20.5 1.1 1 0 0 1 1 1 1 Nuclear protein MDM1 TFIIA PF03153.13 CDJ64808.1 - 0.002 18.2 27.4 0.0023 18.0 27.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.11 CDJ64808.1 - 0.0093 16.2 28.7 0.015 15.5 28.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF755) Sporozoite_P67 PF05642.11 CDJ64808.1 - 0.014 13.5 11.1 0.016 13.3 11.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF45 PF01863.17 CDJ64808.1 - 0.022 14.8 2.0 0.03 14.4 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 Lin-8 PF03353.15 CDJ64808.1 - 0.022 14.3 13.8 0.027 14.0 13.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MPM1 PF17234.2 CDJ64808.1 - 0.025 14.8 10.7 0.035 14.3 10.7 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Apt1 PF10351.9 CDJ64808.1 - 0.026 13.4 11.2 0.027 13.3 11.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cwf_Cwc_15 PF04889.12 CDJ64808.1 - 0.028 14.1 10.3 0.038 13.7 10.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF572 PF04502.13 CDJ64808.1 - 0.044 13.4 8.3 0.052 13.2 8.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) MAP65_ASE1 PF03999.12 CDJ64808.1 - 0.055 12.2 13.9 0.069 11.8 13.9 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) GREB1 PF15782.5 CDJ64808.1 - 0.064 10.4 16.3 0.069 10.3 16.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF908 PF06012.12 CDJ64808.1 - 0.088 12.2 9.5 0.1 12.0 9.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Miga PF10265.9 CDJ64808.1 - 0.092 11.7 11.8 0.1 11.5 11.8 1.1 1 0 0 1 1 1 0 Mitoguardin DUF2722 PF10846.8 CDJ64808.1 - 0.12 11.2 22.4 0.19 10.7 22.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SOG2 PF10428.9 CDJ64808.1 - 0.19 10.9 18.0 0.21 10.7 18.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PI3K_1B_p101 PF10486.9 CDJ64808.1 - 0.23 9.2 10.2 0.29 8.9 10.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Spt20 PF12090.8 CDJ64808.1 - 0.24 11.0 28.5 0.34 10.5 28.5 1.1 1 0 0 1 1 1 0 Spt20 family SPX PF03105.19 CDJ64808.1 - 0.25 11.2 14.9 0.28 11.1 14.9 1.1 1 0 0 1 1 1 0 SPX domain FHIPEP PF00771.20 CDJ64808.1 - 0.26 9.7 3.6 0.36 9.3 3.6 1.2 1 0 0 1 1 1 0 FHIPEP family DUF1635 PF07795.11 CDJ64808.1 - 0.27 11.1 12.8 0.34 10.7 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) BORG_CEP PF14957.6 CDJ64808.1 - 0.28 12.4 11.7 0.45 11.7 11.7 1.3 1 0 0 1 1 1 0 Cdc42 effector CytochromB561_N PF09786.9 CDJ64808.1 - 0.49 9.3 11.8 0.56 9.1 11.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal RAP1 PF07218.11 CDJ64808.1 - 0.49 8.6 16.0 0.65 8.2 16.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1645 PF07816.11 CDJ64808.1 - 0.5 10.9 21.9 0.89 10.1 21.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) Peptidase_S64 PF08192.11 CDJ64808.1 - 0.7 8.3 14.1 0.76 8.2 14.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.9 CDJ64808.1 - 0.87 7.8 16.8 0.93 7.7 16.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dicty_REP PF05086.12 CDJ64808.1 - 1 7.2 5.3 1.3 6.9 5.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Roughex PF06020.11 CDJ64808.1 - 1 8.4 12.9 1.5 7.9 12.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein LCD1 PF09798.9 CDJ64808.1 - 1.3 7.5 7.3 1.5 7.2 7.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein FAM60A PF15396.6 CDJ64808.1 - 1.3 9.0 10.2 1.8 8.5 10.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ64808.1 - 1.3 8.8 10.4 1.7 8.4 10.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ64808.1 - 1.4 7.8 12.1 1.8 7.4 12.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ64808.1 - 1.6 7.4 16.1 1.9 7.2 16.1 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ64808.1 - 1.7 7.6 10.1 2 7.3 10.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 CDJ64808.1 - 1.8 8.6 10.8 2.6 8.1 10.8 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family TMEM51 PF15345.6 CDJ64808.1 - 2.1 8.1 16.5 3.4 7.5 16.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 CCDC24 PF15669.5 CDJ64808.1 - 2.8 7.8 19.0 5.6 6.8 18.7 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Plasmodium_Vir PF05795.11 CDJ64808.1 - 2.9 7.2 11.1 3.7 6.9 11.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SR-25 PF10500.9 CDJ64808.1 - 2.9 7.4 38.2 6.1 6.4 37.1 1.8 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Ndc1_Nup PF09531.10 CDJ64808.1 - 3.1 6.4 17.4 3.5 6.2 17.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ALMT PF11744.8 CDJ64808.1 - 3.3 6.4 9.5 4 6.2 9.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Paf1 PF03985.13 CDJ64808.1 - 4.2 6.3 15.7 5.7 5.8 15.7 1.2 1 0 0 1 1 1 0 Paf1 Herpes_pp85 PF04637.12 CDJ64808.1 - 5.5 5.3 8.6 7 4.9 8.6 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Sec62 PF03839.16 CDJ64808.1 - 5.5 6.4 6.4 7 6.1 6.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Mem_trans PF03547.18 CDJ64808.1 - 5.7 5.2 8.9 8.6 4.6 8.9 1.2 1 0 0 1 1 1 0 Membrane transport protein WASH-7_C PF14746.6 CDJ64808.1 - 6 6.5 8.5 8.3 6.1 8.5 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal DUF4551 PF15087.6 CDJ64808.1 - 7.8 5.2 12.4 8.8 5.0 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Smg8_Smg9 PF10220.9 CDJ64808.1 - 9.7 4.4 12.3 11 4.2 12.3 1.0 1 0 0 1 1 1 0 Smg8_Smg9 V4R PF02830.18 CDJ64809.1 - 0.16 12.0 0.9 0.57 10.2 0.0 2.3 2 0 0 2 2 2 0 V4R domain Macoilin PF09726.9 CDJ64810.1 - 0.21 10.1 40.5 0.24 9.9 40.5 1.1 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CDJ64810.1 - 0.5 10.3 49.1 0.55 10.2 49.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ64810.1 - 0.61 9.6 33.3 0.84 9.1 33.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Med15 PF09606.10 CDJ64810.1 - 1.9 7.1 33.3 2.5 6.7 33.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S64 PF08192.11 CDJ64810.1 - 7.1 5.0 32.0 8.3 4.8 32.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 PEX11 PF05648.14 CDJ64811.1 - 1e-34 120.0 7.4 1.5e-34 119.4 7.4 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4386 PF14329.6 CDJ64811.1 - 1.5 8.7 36.3 0.11 12.4 3.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Spt20 PF12090.8 CDJ64812.1 - 0.26 10.9 18.6 0.36 10.4 18.6 1.2 1 0 0 1 1 1 0 Spt20 family Mitofilin PF09731.9 CDJ64812.1 - 1.1 8.1 20.2 1.2 7.8 20.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Sporozoite_P67 PF05642.11 CDJ64812.1 - 1.8 6.6 9.1 2.2 6.3 9.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ndc1_Nup PF09531.10 CDJ64812.1 - 2.9 6.5 13.2 2.9 6.5 13.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 CDJ64812.1 - 5.1 7.0 25.6 6.4 6.7 25.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.13 CDJ64812.1 - 6.5 5.2 14.7 8 4.9 14.7 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 CDJ64813.1 - 0.00033 19.4 13.3 0.00047 18.9 13.3 1.2 1 0 0 1 1 1 1 Macoilin family Dehydrin PF00257.19 CDJ64813.1 - 0.0015 19.1 10.5 0.0015 19.1 10.5 2.1 2 0 0 2 2 2 1 Dehydrin DUF4611 PF15387.6 CDJ64813.1 - 0.045 14.0 2.1 0.086 13.1 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) EMP24_GP25L PF01105.24 CDJ64813.1 - 0.07 13.1 0.8 0.093 12.7 0.8 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ATG16 PF08614.11 CDJ64813.1 - 0.073 13.3 26.4 0.085 13.1 16.7 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4179 PF13786.6 CDJ64813.1 - 0.091 13.2 4.3 1.8 9.1 4.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Trans_reg_C PF00486.28 CDJ64813.1 - 0.34 11.0 0.1 0.34 11.0 0.1 2.1 2 1 0 2 2 2 0 Transcriptional regulatory protein, C terminal TFIIA PF03153.13 CDJ64813.1 - 1.9 8.4 18.7 2.4 8.0 18.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_9 PF00759.19 CDJ64813.1 - 3 7.2 13.9 3.8 6.8 13.9 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 FAM76 PF16046.5 CDJ64813.1 - 3 7.1 8.7 3.7 6.8 8.7 1.1 1 0 0 1 1 1 0 FAM76 protein Hamartin PF04388.12 CDJ64813.1 - 4.1 5.9 14.7 4.8 5.7 14.7 1.0 1 0 0 1 1 1 0 Hamartin protein Csm1_N PF18504.1 CDJ64813.1 - 6.3 7.2 12.5 0.82 10.0 3.4 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain Pneumo_att_G PF05539.11 CDJ64813.1 - 7.8 6.0 14.8 8.7 5.8 14.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G CENP-H PF05837.12 CDJ64813.1 - 9.4 6.7 15.9 0.81 10.1 10.0 2.1 2 1 1 3 3 3 0 Centromere protein H (CENP-H) FAM117 PF15388.6 CDJ64815.1 - 0.079 12.4 6.3 0.09 12.2 6.3 1.1 1 0 0 1 1 1 0 Protein Family FAM117 T4BSS_DotH_IcmK PF12293.8 CDJ64815.1 - 0.27 10.5 3.0 0.37 10.0 3.0 1.2 1 0 0 1 1 1 0 Putative outer membrane core complex of type IVb secretion CCSAP PF15748.5 CDJ64816.1 - 0.82 9.8 61.4 0.36 11.0 46.4 2.0 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Adaptin_binding PF10199.9 CDJ64817.1 - 6.8e-05 23.5 1.8 0.00012 22.6 1.6 1.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 ETRAMP PF09716.10 CDJ64817.1 - 0.041 14.0 1.0 0.058 13.5 1.0 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4114 PF13448.6 CDJ64817.1 - 0.62 10.9 1.8 1.2 10.0 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) Rtf2 PF04641.12 CDJ64817.1 - 0.91 8.8 16.8 0.07 12.5 0.7 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Suf PF05843.14 CDJ64817.1 - 3.6 7.5 12.7 0.52 10.2 6.6 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4638 PF15472.6 CDJ64817.1 - 6.3 6.5 12.2 8.5 6.0 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) CCDC53 PF10152.9 CDJ64817.1 - 6.9 7.1 20.1 2.6 8.5 10.5 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ctr PF04145.15 CDJ64817.1 - 7.2 7.2 7.6 15 6.2 2.3 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Presenilin PF01080.17 CDJ64817.1 - 7.5 5.2 14.4 0.39 9.4 7.7 1.8 2 0 0 2 2 2 0 Presenilin RasGAP_C PF03836.15 CDJ64818.1 - 0.024 14.8 0.4 0.024 14.8 0.4 1.9 2 0 0 2 2 2 0 RasGAP C-terminus GAS PF13851.6 CDJ64818.1 - 0.06 12.7 19.2 0.11 11.8 19.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PKI PF02827.16 CDJ64818.1 - 1.2 9.4 3.2 5.5 7.3 3.2 2.2 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF5470 PF17564.2 CDJ64818.1 - 4.1 7.7 6.6 7.8 6.8 6.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5470) DUF1645 PF07816.11 CDJ64819.1 - 0.0023 18.5 4.5 0.0023 18.5 4.5 3.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1645) DUF2722 PF10846.8 CDJ64819.1 - 0.0037 16.3 8.0 0.0037 16.3 8.0 4.2 2 1 2 4 4 4 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ64819.1 - 0.075 13.3 0.1 0.075 13.3 0.1 5.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA AF-4 PF05110.13 CDJ64819.1 - 0.19 9.8 60.2 0.17 9.9 10.3 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein SRP-alpha_N PF04086.13 CDJ64819.1 - 1.3 8.9 46.5 3.4 7.5 31.5 2.5 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF4179 PF13786.6 CDJ64819.1 - 6.8 7.2 6.4 1.2 9.7 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) Glycos_transf_2 PF00535.26 CDJ64820.1 - 0.88 9.4 2.3 2.2 8.1 2.3 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 UTP25 PF06862.12 CDJ64821.1 - 9e-76 255.5 0.0 2.3e-38 132.2 0.0 5.4 5 0 0 5 5 5 5 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF4667 PF15700.5 CDJ64821.1 - 0.0004 20.6 12.2 0.0004 20.6 12.2 5.3 2 1 0 3 3 3 1 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ64821.1 - 0.0007 19.6 14.1 0.0007 19.6 14.1 4.1 2 1 0 2 2 2 1 SPX domain BUD22 PF09073.10 CDJ64821.1 - 0.0017 17.8 16.6 0.0017 17.8 16.6 3.7 2 1 0 2 2 2 1 BUD22 TFIIA PF03153.13 CDJ64821.1 - 0.37 10.7 122.3 3.5 7.5 49.4 5.0 2 1 2 4 4 4 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L12_N PF16320.5 CDJ64822.1 - 0.012 15.3 2.7 0.032 14.0 2.7 1.8 1 1 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain ADK_lid PF05191.14 CDJ64822.1 - 0.076 13.0 0.3 0.11 12.5 0.3 1.5 1 1 0 1 1 1 0 Adenylate kinase, active site lid DUF2722 PF10846.8 CDJ64823.1 - 0.0032 16.5 9.8 0.0032 16.5 9.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ64823.1 - 0.0048 17.0 11.5 0.0048 17.0 11.5 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Abhydrolase_1 PF00561.20 CDJ64823.1 - 0.0051 16.5 0.0 0.0051 16.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold U1snRNP70_N PF12220.8 CDJ64823.1 - 0.35 11.5 7.8 0.99 10.1 1.2 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal LEA_3 PF03242.13 CDJ64823.1 - 1.5 9.6 4.6 5.9 7.7 0.2 2.6 2 0 0 2 2 2 0 Late embryogenesis abundant protein Aldo_ket_red PF00248.21 CDJ64825.1 - 7.7e-30 104.1 0.0 1.5e-20 73.6 0.0 2.4 1 1 1 2 2 2 2 Aldo/keto reductase family DUF2722 PF10846.8 CDJ64825.1 - 1.9 7.4 8.6 3.4 6.5 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ABC_tran PF00005.27 CDJ64826.1 - 4e-14 53.3 0.0 4e-13 50.0 0.0 2.5 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 CDJ64826.1 - 0.0012 18.5 0.1 0.0012 18.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CDJ64826.1 - 0.037 14.5 1.7 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CDJ64826.1 - 0.072 13.1 1.3 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 CDJ64826.1 - 0.08 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 CDJ64826.1 - 0.095 12.5 0.0 1.4 8.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CDJ64826.1 - 0.22 11.9 0.0 0.22 11.9 0.0 4.7 6 0 0 6 6 6 0 AAA ATPase domain ABC_tran PF00005.27 CDJ64827.1 - 5.5e-25 88.5 0.0 1.7e-23 83.6 0.0 2.4 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ64827.1 - 8e-05 22.6 0.0 0.046 13.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ64827.1 - 0.003 17.2 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 CDJ64827.1 - 0.0047 16.4 0.0 0.39 10.1 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CDJ64827.1 - 0.0076 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dicer_dimer PF03368.14 CDJ64827.1 - 0.038 14.1 0.1 1.4 9.1 0.0 3.1 3 1 0 3 3 3 0 Dicer dimerisation domain AAA_25 PF13481.6 CDJ64827.1 - 0.05 13.2 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ64827.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 CDJ64827.1 - 0.076 13.4 0.0 0.2 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 CDJ64827.1 - 0.079 13.4 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Tweety PF04906.13 CDJ64828.1 - 0.015 14.0 16.5 0.021 13.5 8.0 3.3 3 0 0 3 3 3 0 Tweety MMR_HSR1 PF01926.23 CDJ64831.1 - 2.7e-17 62.9 0.0 4.8e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ64831.1 - 8.6e-08 31.9 0.0 3.5e-07 29.9 0.1 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ64831.1 - 1.3e-06 28.6 0.4 7.2e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.16 CDJ64831.1 - 3e-05 23.5 0.0 4.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 CDJ64831.1 - 0.00082 19.3 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CDJ64831.1 - 0.0022 17.6 0.0 2.1 7.8 0.0 2.7 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CDJ64831.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CDJ64831.1 - 0.032 14.8 0.0 0.072 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PPV_E1_C PF00519.17 CDJ64831.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_21 PF13304.6 CDJ64831.1 - 0.24 11.2 0.1 0.4 10.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PTH2 PF01981.16 CDJ64832.1 - 8.3e-16 58.3 0.1 1.3e-15 57.7 0.1 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3223 PF11523.8 CDJ64833.1 - 7.6e-13 49.1 0.1 3.7e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3223) FAM60A PF15396.6 CDJ64833.1 - 1 9.3 6.1 1.6 8.7 6.1 1.4 1 0 0 1 1 1 0 Protein Family FAM60A PPP4R2 PF09184.11 CDJ64833.1 - 2.6 7.6 7.4 3.2 7.3 7.4 1.1 1 0 0 1 1 1 0 PPP4R2 BAF1_ABF1 PF04684.13 CDJ64833.1 - 4.3 6.3 19.2 6.9 5.6 19.2 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RR_TM4-6 PF06459.12 CDJ64833.1 - 5.6 6.7 16.1 8.4 6.1 16.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RIFIN PF02009.16 CDJ64833.1 - 7.4 6.4 14.5 12 5.6 14.5 1.3 1 0 0 1 1 1 0 Rifin SR-25 PF10500.9 CDJ64834.1 - 0.00057 19.6 21.9 0.00068 19.3 21.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4207 PF13904.6 CDJ64834.1 - 0.66 9.6 37.4 0.87 9.2 37.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) RR_TM4-6 PF06459.12 CDJ64834.1 - 1.3 8.8 20.9 1.6 8.5 20.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 CDJ64834.1 - 2.2 7.1 16.8 2.6 6.9 16.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pex14_N PF04695.13 CDJ64834.1 - 2.4 8.8 29.8 3.9 8.1 29.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Velvet PF11754.8 CDJ64834.1 - 2.8 7.8 23.5 3.3 7.6 23.5 1.1 1 0 0 1 1 1 0 Velvet factor PIP5K PF01504.18 CDJ64834.1 - 3 7.0 14.7 3.5 6.8 14.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase eIF-3_zeta PF05091.12 CDJ64834.1 - 3.2 6.6 24.9 3.6 6.5 24.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.13 CDJ64834.1 - 4 7.2 21.7 4.5 7.0 21.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spem1 PF15670.5 CDJ64834.1 - 4 6.9 22.0 4.7 6.7 22.0 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Bul1_N PF04425.12 CDJ64834.1 - 4.5 5.9 15.7 4.8 5.8 15.7 1.1 1 0 0 1 1 1 0 Bul1 N terminus Endostatin PF06482.11 CDJ64834.1 - 4.9 6.5 20.0 5.6 6.3 20.0 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CDC45 PF02724.14 CDJ64834.1 - 5.1 5.3 22.3 5.4 5.2 22.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 CDJ64834.1 - 6.5 5.6 14.2 7.6 5.4 14.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2126 PF09899.9 CDJ64834.1 - 6.6 4.7 13.8 6.9 4.6 13.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Presenilin PF01080.17 CDJ64834.1 - 9 4.9 28.8 9.9 4.8 28.8 1.0 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 CDJ64834.1 - 9.3 4.6 20.6 11 4.4 20.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Inositol_P PF00459.25 CDJ64836.1 - 1.1e-32 113.7 0.0 9.7e-27 94.2 0.3 3.2 2 1 0 2 2 2 2 Inositol monophosphatase family FBPase PF00316.20 CDJ64836.1 - 0.077 12.5 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Fructose-1-6-bisphosphatase, N-terminal domain GHMP_kinases_N PF00288.26 CDJ64837.1 - 0.012 15.8 16.3 2.2 8.6 0.5 3.7 3 0 0 3 3 3 0 GHMP kinases N terminal domain DUF4148 PF13663.6 CDJ64837.1 - 0.074 13.2 22.7 1.9 8.7 1.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) RskA PF10099.9 CDJ64837.1 - 0.3 11.4 37.3 0.044 14.1 4.5 3.3 1 1 2 3 3 3 0 Anti-sigma-K factor rskA Mit_KHE1 PF10173.9 CDJ64837.1 - 1.5 8.8 8.1 2 8.4 8.1 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related PepSY_2 PF13670.6 CDJ64837.1 - 1.9 8.5 36.7 2.5 8.1 7.2 3.2 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain CRF1 PF10380.9 CDJ64837.1 - 6 7.3 11.5 9.2 6.7 1.8 2.7 1 1 0 2 2 2 0 Transcription factor CRF1 PGAP1 PF07819.13 CDJ64838.1 - 3.7e-12 46.5 0.0 3.7e-12 46.5 0.0 2.9 2 0 0 2 2 2 1 PGAP1-like protein Spt20 PF12090.8 CDJ64838.1 - 0.0005 19.8 6.7 0.0005 19.8 6.7 18.4 13 5 1 14 14 14 3 Spt20 family RskA PF10099.9 CDJ64838.1 - 0.00067 20.0 0.2 0.00067 20.0 0.2 29.5 6 6 14 21 21 21 3 Anti-sigma-K factor rskA TMEM51 PF15345.6 CDJ64838.1 - 0.0013 18.6 0.5 0.0013 18.6 0.5 13.7 13 2 1 14 14 14 1 Transmembrane protein 51 Lin-8 PF03353.15 CDJ64838.1 - 0.0022 17.6 3.8 0.0022 17.6 3.8 13.1 11 1 2 13 13 13 3 Ras-mediated vulval-induction antagonist DUF4834 PF16118.5 CDJ64838.1 - 0.004 18.1 0.9 0.004 18.1 0.9 17.4 19 2 0 19 19 19 1 Domain of unknown function (DUF4834) DUF676 PF05057.14 CDJ64838.1 - 0.041 13.4 0.1 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF4964 PF16334.5 CDJ64838.1 - 0.28 10.8 2.3 2.7 7.6 0.3 3.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4964) NIF PF03031.18 CDJ64840.1 - 9.5e-05 22.2 0.1 0.00097 18.9 0.0 2.2 2 1 1 3 3 3 1 NLI interacting factor-like phosphatase DUF2057 PF09829.9 CDJ64840.1 - 0.0095 16.1 1.2 0.0095 16.1 1.2 2.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2057) Nrap_D4 PF17405.2 CDJ64842.1 - 8.7e-27 93.9 0.2 1.6e-26 93.0 0.2 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 CDJ64842.1 - 6.6e-20 71.5 0.1 2.1e-15 56.9 0.0 2.8 2 1 1 3 3 3 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 CDJ64842.1 - 1.2e-16 61.3 0.0 5.9e-16 59.0 0.0 2.2 3 0 0 3 3 3 1 Nrap protein domain 3 Nrap PF03813.14 CDJ64842.1 - 3.5e-16 59.6 0.0 2.7e-15 56.7 0.0 2.2 1 1 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 CDJ64842.1 - 1.8e-11 44.0 4.9 1.6e-10 41.0 0.9 3.5 2 2 0 2 2 2 1 Nrap protein PAP/OAS-like domain RskA PF10099.9 CDJ64842.1 - 0.58 10.4 12.5 3.6 7.9 2.4 3.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Sec7_N PF12783.7 CDJ64843.1 - 0.099 12.5 0.5 0.92 9.4 0.0 2.7 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal UPF0242 PF06785.11 CDJ64843.1 - 0.15 12.2 18.2 0.55 10.3 1.9 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PASTA PF03793.19 CDJ64843.1 - 0.42 10.5 1.9 2.6 8.0 1.9 2.4 1 0 0 1 1 1 0 PASTA domain Ank_4 PF13637.6 CDJ64844.1 - 6.2e-21 74.5 0.3 5e-13 49.3 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ64844.1 - 1.5e-20 73.6 0.0 2.5e-10 40.8 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ64844.1 - 9.5e-19 67.0 0.5 0.00033 21.0 0.0 6.0 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CDJ64844.1 - 1.7e-18 64.7 0.2 4.8e-05 23.5 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CDJ64844.1 - 9.3e-14 51.3 0.2 1.5e-07 31.5 0.0 4.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) FapA PF03961.13 CDJ64846.1 - 7 5.1 13.7 10 4.6 13.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TPH PF13868.6 CDJ64847.1 - 1.9e-45 154.9 145.3 1.9e-45 154.9 145.3 2.3 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain RPAP2_Rtr1 PF04181.13 CDJ64848.1 - 5e-08 33.2 1.3 5e-08 33.2 1.3 2.1 2 0 0 2 2 2 1 Rtr1/RPAP2 family Cpn10 PF00166.21 CDJ64849.1 - 1.6e-17 63.3 0.0 1.9e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit ThiF PF00899.21 CDJ64850.1 - 1.3e-46 158.9 0.1 2.1e-46 158.3 0.1 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CDJ64850.1 - 6e-05 23.3 0.1 0.26 11.5 0.0 2.5 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CDJ64850.1 - 0.0056 17.1 0.0 0.019 15.4 0.0 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding Arm PF00514.23 CDJ64851.1 - 2.8e-06 27.2 9.1 0.31 11.2 0.0 9.2 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDJ64851.1 - 0.039 14.3 13.9 0.19 12.2 0.1 6.0 4 1 1 5 5 5 0 HEAT repeats Speriolin_C PF15059.6 CDJ64851.1 - 0.076 13.1 0.0 6.8 6.8 0.0 2.9 2 0 0 2 2 2 0 Speriolin C-terminus AAA PF00004.29 CDJ64853.1 - 1.2e-42 145.4 0.0 1.7e-36 125.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ64853.1 - 5.2e-09 35.8 0.0 0.0032 17.2 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain IstB_IS21 PF01695.17 CDJ64853.1 - 1.5e-07 31.4 0.1 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 CDJ64853.1 - 3e-06 27.7 1.7 0.1 13.0 0.1 3.7 3 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CDJ64853.1 - 6.7e-05 23.2 0.1 0.39 11.0 0.1 3.7 3 1 1 4 4 3 1 AAA domain RNA_helicase PF00910.22 CDJ64853.1 - 0.00021 21.7 0.0 0.26 11.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 CDJ64853.1 - 0.00054 20.1 0.0 0.0046 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ64853.1 - 0.00091 19.8 0.0 0.25 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CDJ64853.1 - 0.0094 16.5 0.0 3 8.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.14 CDJ64853.1 - 0.01 15.9 0.4 0.23 11.5 0.1 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 CDJ64853.1 - 0.016 14.7 0.1 0.25 10.8 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 CDJ64853.1 - 0.02 15.1 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CDJ64853.1 - 0.023 14.3 0.4 0.84 9.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ64853.1 - 0.057 13.3 0.1 3.1 7.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 CDJ64853.1 - 0.059 13.3 0.2 5.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain RuvB_N PF05496.12 CDJ64853.1 - 0.061 13.1 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CDJ64853.1 - 0.092 12.1 0.7 0.21 10.9 0.2 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CDJ64853.1 - 0.15 11.3 0.0 0.4 9.9 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin ParA PF10609.9 CDJ64853.1 - 0.19 11.1 0.1 0.48 9.8 0.0 1.6 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase PEX-1N PF09262.11 CDJ64854.1 - 1.7e-15 57.2 0.0 4.3e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal ACBP PF00887.19 CDJ64855.1 - 1.5e-22 79.6 1.4 5.8e-22 77.7 1.4 2.1 1 0 0 1 1 1 1 Acyl CoA binding protein RRP36 PF06102.12 CDJ64855.1 - 0.1 12.5 0.1 0.1 12.5 0.1 3.4 4 0 0 4 4 4 0 rRNA biogenesis protein RRP36 SAGA-Tad1 PF12767.7 CDJ64855.1 - 6.1 6.5 19.2 0.11 12.3 1.7 2.9 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit Tam41_Mmp37 PF09139.11 CDJ64856.1 - 2.3e-51 175.2 0.0 3.8e-51 174.5 0.0 1.3 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial SSF PF00474.17 CDJ64857.1 - 1.2e-14 54.1 19.3 3.7e-14 52.4 19.3 1.9 1 1 0 1 1 1 1 Sodium:solute symporter family DUF2561 PF10812.8 CDJ64857.1 - 0.00019 21.5 0.5 0.00087 19.4 0.5 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) GNAT_acetyltr_2 PF13718.6 CDJ64858.1 - 2.4e-81 272.5 0.0 4.9e-55 186.4 0.0 2.4 2 0 0 2 2 2 2 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 CDJ64858.1 - 7.3e-56 188.8 0.0 2.4e-55 187.1 0.0 2.0 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 CDJ64858.1 - 2.8e-42 145.0 0.0 2.8e-42 145.0 0.0 2.2 2 0 0 2 2 2 1 Possible tRNA binding domain DUF1726 PF08351.11 CDJ64858.1 - 5.8e-23 80.6 0.0 1.3e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_19 PF13245.6 CDJ64858.1 - 8.1e-05 23.0 0.0 0.00025 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Acetyltransf_1 PF00583.25 CDJ64858.1 - 0.00091 19.4 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AAA_30 PF13604.6 CDJ64858.1 - 0.0013 18.5 0.4 0.0013 18.5 0.4 3.6 2 1 1 3 3 3 1 AAA domain Acetyltransf_7 PF13508.7 CDJ64858.1 - 0.039 14.4 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PCMT PF01135.19 CDJ64859.1 - 1.2e-39 136.3 0.0 1.2e-39 136.3 0.0 2.0 2 1 0 2 2 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CDJ64859.1 - 1.2e-06 28.4 0.5 2.9e-06 27.2 0.5 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ64859.1 - 0.0062 16.4 0.0 0.017 14.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ64859.1 - 0.011 16.4 0.1 0.057 14.1 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ64859.1 - 0.014 15.3 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 1 0 Methyltransferase domain ASFV_J13L PF05568.11 CDJ64859.1 - 0.039 13.7 2.1 0.081 12.7 2.1 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Methyltransf_11 PF08241.12 CDJ64859.1 - 0.045 14.4 0.0 0.17 12.5 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain V_ATPase_I PF01496.19 CDJ64859.1 - 4.9 4.9 12.4 5.8 4.7 12.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EOS1 PF12326.8 CDJ64859.1 - 5.7 6.8 6.1 8.9 6.2 6.1 1.3 1 0 0 1 1 1 0 N-glycosylation protein Baculo_PP31 PF05311.11 CDJ64859.1 - 5.7 6.3 14.2 7.4 6.0 14.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Serinc PF03348.15 CDJ64859.1 - 9.4 5.0 6.5 12 4.7 6.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Chorein_N PF12624.7 CDJ64862.1 - 8.4e-19 67.8 0.0 8.4e-19 67.8 0.0 5.0 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CDJ64862.1 - 7.3e-13 48.7 0.0 2.5e-12 47.0 0.0 2.0 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CDJ64862.1 - 1.7e-08 34.6 0.0 1.7e-07 31.3 0.0 2.5 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 CDJ64862.1 - 2.1e-06 27.3 0.0 1.6e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 Kinesin PF00225.23 CDJ64864.1 - 8.6e-41 140.0 0.2 8.6e-41 140.0 0.2 4.5 3 1 2 5 5 5 1 Kinesin motor domain EFP_N PF08207.12 CDJ64865.1 - 1.8e-05 24.7 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain DUF2993 PF11209.8 CDJ64865.1 - 0.0033 17.7 0.0 0.0049 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2993) EFP PF01132.20 CDJ64865.1 - 0.016 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain Ribosomal_60s PF00428.19 CDJ64865.1 - 1.6 9.4 10.6 3 8.5 10.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein ATP_bind_3 PF01171.20 CDJ64866.1 - 1.8e-16 60.5 0.1 8.1e-08 32.2 0.2 3.6 3 1 0 3 3 3 2 PP-loop family zn-ribbon_14 PF16503.5 CDJ64866.1 - 1.7e-05 24.2 1.0 1.7e-05 24.2 1.0 2.8 3 0 0 3 3 3 1 Zinc-ribbon Sporozoite_P67 PF05642.11 CDJ64866.1 - 0.00036 18.8 0.0 0.00036 18.8 0.0 4.8 3 2 1 4 4 4 1 Sporozoite P67 surface antigen DUF2201_N PF13203.6 CDJ64866.1 - 0.012 15.3 2.2 0.012 15.3 2.2 2.6 3 0 0 3 3 3 0 Putative metallopeptidase domain AAA_23 PF13476.6 CDJ64866.1 - 0.027 15.0 10.0 2.3 8.7 6.6 2.3 2 0 0 2 2 2 0 AAA domain PAPS_reduct PF01507.19 CDJ64866.1 - 0.095 12.7 0.1 0.28 11.2 0.1 1.9 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family EIIBC-GUT_N PF03612.14 CDJ64866.1 - 7.5 6.3 11.4 0.033 14.0 0.9 2.3 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus CAF1 PF04857.20 CDJ64867.1 - 0.0074 15.5 0.0 0.0074 15.5 0.0 4.9 4 1 0 4 4 4 2 CAF1 family ribonuclease DNA_pol3_a_NII PF11490.8 CDJ64867.1 - 0.034 14.1 0.3 0.034 14.1 0.3 8.9 11 0 0 11 11 11 0 DNA polymerase III polC-type N-terminus II zf-C2H2_jaz PF12171.8 CDJ64868.1 - 0.0022 18.2 0.4 0.0022 18.2 0.4 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CDJ64868.1 - 0.021 15.6 2.7 0.24 12.3 0.2 4.8 6 0 0 6 6 6 0 C2H2-type zinc finger S1 PF00575.23 CDJ64869.1 - 2.4e-13 50.2 0.3 2.6e-05 24.5 0.1 4.0 3 1 0 3 3 3 3 S1 RNA binding domain S1_2 PF13509.6 CDJ64869.1 - 0.0032 17.5 0.0 0.0058 16.7 0.0 1.4 1 0 0 1 1 1 1 S1 domain SR-25 PF10500.9 CDJ64869.1 - 0.06 12.9 7.4 0.19 11.3 7.4 1.8 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ64870.1 - 0.0028 17.7 10.5 0.018 15.1 10.5 2.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 SNF2_N PF00176.23 CDJ64870.1 - 0.0048 15.7 0.0 0.0087 14.8 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF4667 PF15700.5 CDJ64870.1 - 0.0097 16.0 21.3 0.035 14.2 0.2 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF4667) PRP21_like_P PF12230.8 CDJ64870.1 - 0.15 12.0 3.0 0.23 11.3 3.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Spt20 PF12090.8 CDJ64870.1 - 0.17 11.4 9.2 0.36 10.4 8.9 1.7 2 0 0 2 2 2 0 Spt20 family Endostatin PF06482.11 CDJ64870.1 - 1.2 8.5 8.6 0.88 9.0 4.0 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Spt20 PF12090.8 CDJ64872.1 - 0.024 14.2 15.2 0.02 14.5 15.2 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ64872.1 - 2.5 8.0 16.8 2.5 8.0 16.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Laminin_B PF00052.18 CDJ64873.1 - 5.2 7.0 10.9 0.14 12.1 0.6 2.7 2 1 1 3 3 3 0 Laminin B (Domain IV) LNS2 PF08235.13 CDJ64874.1 - 1.4e-63 214.4 0.0 2e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DUF3824 PF12868.7 CDJ64875.1 - 0.087 13.5 6.2 3.9 8.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) SR-25 PF10500.9 CDJ64875.1 - 0.34 10.5 21.0 0.043 13.4 17.2 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 CDJ64875.1 - 3.3 7.4 7.0 6.1 6.5 7.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Spt20 PF12090.8 CDJ64876.1 - 0.043 13.4 1.8 0.047 13.3 1.8 1.2 1 0 0 1 1 1 0 Spt20 family Ribosomal_60s PF00428.19 CDJ64877.1 - 0.022 15.3 8.4 0.022 15.3 8.4 5.7 4 2 1 5 5 5 0 60s Acidic ribosomal protein PAS PF00989.25 CDJ64878.1 - 0.0065 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold Spt20 PF12090.8 CDJ64878.1 - 0.074 12.7 13.0 0.088 12.4 13.0 1.1 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ64878.1 - 0.19 12.7 1.2 0.29 12.1 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) eIF-3_zeta PF05091.12 CDJ64878.1 - 0.21 10.5 2.8 0.22 10.4 2.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TMEM65 PF10507.9 CDJ64878.1 - 0.29 11.1 0.1 0.29 11.1 0.1 2.4 2 1 1 3 3 3 0 Transmembrane protein 65 RIFIN PF02009.16 CDJ64878.1 - 0.34 10.8 6.9 0.4 10.5 6.9 1.1 1 0 0 1 1 1 0 Rifin Neur_chan_memb PF02932.16 CDJ64878.1 - 0.39 10.7 1.8 0.46 10.5 1.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ64878.1 - 0.39 10.7 18.2 0.4 10.6 18.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5345 PF17280.2 CDJ64878.1 - 4 7.5 9.2 9.2 6.3 9.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5345) LRR_6 PF13516.6 CDJ64879.1 - 3.1e-05 23.7 2.4 0.95 9.7 0.2 3.6 3 0 0 3 3 3 2 Leucine Rich repeat CemA PF03040.14 CDJ64879.1 - 0.29 11.0 1.4 0.84 9.5 1.4 1.7 1 0 0 1 1 1 0 CemA family MMR_HSR1_C PF08438.10 CDJ64882.1 - 1e-23 84.0 0.0 2e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CDJ64882.1 - 6.9e-19 68.0 0.0 1.7e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ64882.1 - 3.1e-06 26.8 0.1 9.4e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 CDJ64882.1 - 0.0014 18.6 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain ATP_bind_1 PF03029.17 CDJ64882.1 - 0.1 12.4 1.7 2 8.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_pol_Rpc82 PF05645.13 CDJ64883.1 - 0.073 12.8 0.9 13 5.4 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 Spem1 PF15670.5 CDJ64883.1 - 0.4 10.2 6.1 0.11 12.0 0.9 2.4 2 0 0 2 2 2 0 Spermatid maturation protein 1 Herpes_DNAp_acc PF04929.12 CDJ64883.1 - 0.41 9.6 5.1 0.95 8.4 5.1 1.5 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PIG-L PF02585.17 CDJ64883.1 - 0.73 10.5 3.5 0.71 10.5 0.1 2.6 3 0 0 3 3 3 0 GlcNAc-PI de-N-acetylase RRM_1 PF00076.22 CDJ64884.1 - 2.3e-39 133.1 0.0 1.4e-20 72.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ64884.1 - 1e-07 31.6 0.0 0.0073 15.9 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ64884.1 - 0.0004 20.4 0.1 0.15 12.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 CDJ64884.1 - 0.0078 15.9 0.1 4.4 7.1 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain Amino_oxidase PF01593.24 CDJ64885.1 - 1.3e-14 54.4 18.4 8.3e-05 22.0 3.2 3.6 4 0 0 4 4 4 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ64885.1 - 1.9e-08 34.4 0.9 1.9e-08 34.4 0.9 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ64885.1 - 5.2e-05 22.6 0.6 5.2e-05 22.6 0.6 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ64885.1 - 0.00038 21.0 2.1 0.00081 19.9 2.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ64885.1 - 0.00045 19.0 1.8 0.00074 18.3 1.8 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 CDJ64885.1 - 0.0027 17.3 5.3 0.0027 17.3 5.3 3.0 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CDJ64885.1 - 0.011 15.1 2.6 0.02 14.2 2.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ64885.1 - 0.11 11.7 2.4 0.21 10.8 2.4 1.3 1 0 0 1 1 1 0 Thi4 family Hydrolase_4 PF12146.8 CDJ64886.1 - 2.7e-22 79.2 0.2 7.1e-11 41.8 0.0 3.5 3 1 0 3 3 3 2 Serine aminopeptidase, S33 COPI_assoc PF08507.10 CDJ64887.1 - 1e-10 41.8 4.2 1.3e-10 41.4 4.2 1.1 1 0 0 1 1 1 1 COPI associated protein Mannosyl_trans4 PF15971.5 CDJ64887.1 - 0.22 11.4 0.2 0.22 11.4 0.2 2.0 1 1 1 2 2 2 0 DolP-mannose mannosyltransferase GTP_EFTU PF00009.27 CDJ64890.1 - 2.1e-17 63.3 0.0 8.6e-09 35.2 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain UbiA PF01040.18 CDJ64892.1 - 7.3e-33 113.9 27.8 8.5e-26 90.8 11.2 3.0 3 0 0 3 3 3 2 UbiA prenyltransferase family SR-25 PF10500.9 CDJ64892.1 - 0.8 9.3 4.2 1.2 8.7 4.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ64892.1 - 6.1 7.0 8.4 10 6.3 8.4 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ64893.1 - 1.4e-06 28.6 13.0 2.1e-06 28.0 13.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ64893.1 - 0.00034 20.3 21.0 0.00054 19.7 21.0 1.3 1 0 0 1 1 1 1 Spt20 family CCDC117 PF15810.5 CDJ64893.1 - 0.046 14.0 7.8 0.079 13.3 7.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 SpoIIIAH PF12685.7 CDJ64893.1 - 0.44 10.3 18.4 0.78 9.5 18.4 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Presenilin PF01080.17 CDJ64893.1 - 0.63 8.7 17.7 0.96 8.1 17.7 1.2 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 CDJ64893.1 - 0.85 9.5 19.7 1.9 8.3 19.7 1.5 1 0 0 1 1 1 0 SPX domain DUF4407 PF14362.6 CDJ64893.1 - 1.7 7.9 5.7 2.7 7.2 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SR-25 PF10500.9 CDJ64893.1 - 2.3 7.8 58.2 0.45 10.1 35.9 2.3 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.13 CDJ64893.1 - 2.8 6.9 14.8 3.8 6.5 14.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Cyto_heme_lyase PF01265.17 CDJ64893.1 - 3.6 7.1 10.6 6.6 6.2 10.6 1.4 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase DUF4647 PF15504.6 CDJ64893.1 - 9.7 5.2 19.8 14 4.7 19.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) RskA PF10099.9 CDJ64894.1 - 1.2e-06 29.0 10.2 1.2e-06 29.0 10.2 2.1 1 1 0 2 2 2 1 Anti-sigma-K factor rskA Bac_luciferase PF00296.20 CDJ64894.1 - 0.091 12.2 8.4 0.041 13.3 3.3 2.0 2 0 0 2 2 2 0 Luciferase-like monooxygenase Spt20 PF12090.8 CDJ64894.1 - 1 8.9 14.9 2 8.0 14.9 1.4 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 CDJ64894.1 - 4.1 8.0 15.5 2.3 8.8 2.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s PF00428.19 CDJ64894.1 - 4.5 7.9 28.4 2.2 8.9 8.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ64894.1 - 9.7 6.1 19.2 16 5.3 19.2 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK5_activator PF03261.15 CDJ64896.1 - 7.4 6.0 9.0 8.4 5.8 9.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein COG5 PF10392.9 CDJ64897.1 - 0.0028 17.8 1.2 0.0041 17.3 1.2 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 GAS PF13851.6 CDJ64897.1 - 0.0041 16.5 10.7 0.0052 16.2 10.7 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 CDJ64897.1 - 0.0046 16.3 14.0 0.0046 16.3 14.0 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF3450) Chibby PF14645.6 CDJ64897.1 - 0.012 16.0 0.1 0.018 15.5 0.1 1.3 1 0 0 1 1 1 0 Chibby family YabA PF06156.13 CDJ64897.1 - 0.036 14.7 1.3 0.036 14.7 1.3 2.0 1 1 1 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 CDJ64897.1 - 0.098 13.2 13.2 0.19 12.2 13.3 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF5082 PF16888.5 CDJ64897.1 - 0.11 12.8 5.9 0.11 12.8 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) LapA_dom PF06305.11 CDJ64897.1 - 0.13 12.1 0.2 0.13 12.1 0.2 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF2070 PF09843.9 CDJ64897.1 - 0.21 9.8 3.9 0.23 9.7 3.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cnn_1N PF07989.11 CDJ64897.1 - 1.1 9.5 5.4 0.47 10.7 0.6 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 CDJ64897.1 - 1.9 7.3 11.3 2.3 7.0 11.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 CDJ64897.1 - 3.7 7.8 6.2 7.9 6.8 0.9 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Abhydrolase_9_N PF15420.6 CDJ64897.1 - 4.6 7.2 19.2 6.7 6.7 19.2 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus CLZ PF16526.5 CDJ64897.1 - 5.3 7.5 9.5 2.6 8.4 0.9 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Abhydrolase_4 PF08386.10 CDJ64898.1 - 0.014 15.5 0.9 0.014 15.5 0.9 2.1 2 1 0 2 2 2 0 TAP-like protein SUIM_assoc PF16619.5 CDJ64898.1 - 0.053 13.6 9.0 0.058 13.5 5.2 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 BrkDBD PF09607.10 CDJ64898.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.3 2 0 0 2 2 2 0 Brinker DNA-binding domain TFIIA PF03153.13 CDJ64898.1 - 0.25 11.3 8.2 0.29 11.1 8.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ64898.1 - 9.1 5.8 9.7 0.44 10.1 4.1 1.6 2 0 0 2 2 2 0 Spt20 family ATP11 PF06644.11 CDJ64899.1 - 2.6e-10 40.6 7.0 8.5e-05 22.5 0.0 2.9 1 1 2 3 3 3 2 ATP11 protein SUIM_assoc PF16619.5 CDJ64899.1 - 0.15 12.1 9.7 0.16 12.0 5.2 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Sec1 PF00995.23 CDJ64900.1 - 6.7e-29 101.6 0.0 3.3e-21 76.1 0.0 3.0 2 1 1 3 3 3 2 Sec1 family DUF2722 PF10846.8 CDJ64900.1 - 9.9e-05 21.5 2.5 0.00011 21.3 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ64900.1 - 0.0029 17.7 6.1 0.0031 17.6 6.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ64900.1 - 0.024 14.3 14.2 0.033 13.8 14.2 1.2 1 0 0 1 1 1 0 Spt20 family UPF0560 PF10577.9 CDJ64900.1 - 0.079 11.5 4.5 0.1 11.1 4.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4834 PF16118.5 CDJ64900.1 - 0.14 13.2 0.9 0.21 12.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FTZ PF03867.14 CDJ64900.1 - 0.16 11.4 5.5 0.27 10.8 5.5 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Calpain_inhib PF00748.19 CDJ64900.1 - 1.2 9.7 5.7 2.5 8.6 5.7 1.5 1 0 0 1 1 1 0 Calpain inhibitor DUF5421 PF17458.2 CDJ64900.1 - 2.5 7.4 7.1 3.9 6.8 7.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Roughex PF06020.11 CDJ64900.1 - 6.3 5.8 6.3 9.2 5.3 6.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Tubulin PF00091.25 CDJ64901.1 - 3.2e-14 53.6 0.0 4.2e-11 43.4 0.0 2.9 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Presenilin PF01080.17 CDJ64902.1 - 1.3 7.7 26.4 0.096 11.4 3.4 2.2 2 0 0 2 2 2 0 Presenilin ELH PF02323.15 CDJ64903.1 - 0.074 12.4 2.9 0.079 12.3 2.9 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor RRM_1 PF00076.22 CDJ64904.1 - 2.4e-48 161.8 0.1 3.3e-16 58.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ64904.1 - 8.6e-09 35.4 0.1 0.03 14.4 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif WW PF00397.26 CDJ64904.1 - 6.4e-05 22.9 0.9 0.00013 22.0 0.9 1.5 1 0 0 1 1 1 1 WW domain RNA_bind PF08675.11 CDJ64904.1 - 0.057 13.5 0.0 2.6 8.1 0.0 3.1 3 1 0 3 3 3 0 RNA binding domain RskA PF10099.9 CDJ64905.1 - 0.39 11.0 3.6 0.64 10.3 3.6 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA FRG2 PF15315.6 CDJ64906.1 - 0.021 15.0 1.9 2.9 8.1 0.2 2.0 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 Trp_oprn_chp PF09534.10 CDJ64906.1 - 0.057 13.2 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TFIIA PF03153.13 CDJ64906.1 - 1.5 8.7 9.1 1.6 8.6 9.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC2_membrane_2 PF12679.7 CDJ64907.1 - 0.17 11.1 0.2 0.29 10.4 0.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein YgbB PF02542.16 CDJ64908.1 - 1.5e-46 158.5 0.5 5e-45 153.5 0.5 2.2 1 1 0 1 1 1 1 YgbB family RNA_pol PF00940.19 CDJ64909.1 - 4.9e-134 447.3 0.0 1.3e-133 445.9 0.0 1.8 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CDJ64909.1 - 1.1e-13 51.3 11.9 7.4e-09 35.4 0.2 6.6 5 2 1 6 6 6 3 DNA-directed RNA polymerase N-terminal YcgR PF07317.12 CDJ64909.1 - 0.0047 16.8 0.1 0.021 14.7 0.1 2.3 1 0 0 1 1 1 1 Flagellar regulator YcgR Peptidase_C15 PF01470.17 CDJ64912.1 - 5.1e-16 59.4 0.0 2.5e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 Pyroglutamyl peptidase Cluap1 PF10234.9 CDJ64913.1 - 1.9e-10 40.6 15.8 1.1e-08 34.9 0.8 2.6 3 0 0 3 3 3 2 Clusterin-associated protein-1 FlaC_arch PF05377.11 CDJ64913.1 - 0.0047 17.3 1.0 0.018 15.4 0.8 2.2 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) HALZ PF02183.18 CDJ64913.1 - 0.13 12.5 0.4 0.13 12.5 0.4 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper BST2 PF16716.5 CDJ64913.1 - 0.19 12.4 12.7 6.1 7.5 3.9 3.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Fmp27_SW PF10305.9 CDJ64913.1 - 0.44 11.3 2.0 1.1 9.9 0.0 2.6 3 1 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain TMCO5 PF14992.6 CDJ64913.1 - 0.54 9.8 13.8 0.18 11.4 9.2 2.1 1 1 0 2 2 2 0 TMCO5 family FAM76 PF16046.5 CDJ64913.1 - 5.6 6.2 8.9 2.8 7.2 6.3 1.8 1 1 1 2 2 2 0 FAM76 protein Helicase_C PF00271.31 CDJ64914.1 - 2.7e-26 92.1 0.0 7.1e-26 90.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ64914.1 - 1.3e-15 57.6 0.0 3.2e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Apt1 PF10351.9 CDJ64916.1 - 0.74 8.6 27.3 0.45 9.3 14.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain SOBP PF15279.6 CDJ64916.1 - 6.5 7.3 35.3 7.9 7.0 15.5 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Guanylate_cyc_2 PF09778.9 CDJ64918.1 - 5.7e-27 94.5 0.2 1.7e-18 66.8 0.0 3.3 3 0 0 3 3 3 3 Guanylylate cyclase Peptidase_C39 PF03412.15 CDJ64918.1 - 0.025 14.4 0.2 0.025 14.4 0.2 2.1 3 0 0 3 3 3 0 Peptidase C39 family Phytochelatin PF05023.14 CDJ64918.1 - 0.056 12.7 0.8 0.14 11.4 0.8 1.7 1 0 0 1 1 1 0 Phytochelatin synthase DUF3335 PF11814.8 CDJ64918.1 - 0.089 12.2 6.2 0.19 11.2 0.0 2.8 3 0 0 3 3 3 0 Peptidase_C39 like family RRM_1 PF00076.22 CDJ64919.1 - 2.4e-09 36.9 0.0 4.7e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ64919.1 - 6.2e-07 29.2 0.0 8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ64919.1 - 1.6e-05 24.5 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF515 PF04415.12 CDJ64919.1 - 0.016 13.7 1.1 0.017 13.5 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Limkain-b1 PF11608.8 CDJ64919.1 - 0.063 13.4 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 Limkain b1 RRM_8 PF11835.8 CDJ64919.1 - 0.066 13.4 0.0 0.085 13.1 0.0 1.3 1 1 0 1 1 1 0 RRM-like domain DUF3446 PF11928.8 CDJ64919.1 - 1.5 9.2 14.4 2.2 8.7 14.4 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain HEAT PF02985.22 CDJ64920.1 - 0.12 12.7 4.7 20 5.8 0.1 4.5 5 0 0 5 5 5 0 HEAT repeat Glyphos_transf PF04464.14 CDJ64922.1 - 0.04 12.9 0.4 0.059 12.3 0.4 1.3 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Pex26 PF07163.12 CDJ64922.1 - 0.043 13.1 0.3 0.043 13.1 0.3 3.1 3 0 0 3 3 3 0 Pex26 protein Nucleoporin_FG PF13634.6 CDJ64922.1 - 0.59 11.0 18.9 0.35 11.7 14.5 2.3 2 0 0 2 2 2 0 Nucleoporin FG repeat region LCD1 PF09798.9 CDJ64922.1 - 0.72 8.3 9.5 0.97 7.9 9.5 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein Cnd2 PF05786.14 CDJ64923.1 - 2e-29 102.8 9.6 3.7e-22 78.8 8.3 4.4 3 2 1 4 4 4 2 Condensin complex subunit 2 RskA PF10099.9 CDJ64923.1 - 4.6e-06 27.0 62.4 0.49 10.7 0.0 5.8 4 2 1 5 5 5 4 Anti-sigma-K factor rskA CNDH2_N PF06278.11 CDJ64923.1 - 0.00036 20.7 2.0 0.00036 20.7 2.0 5.4 5 0 0 5 5 5 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Chalcone_3 PF16036.5 CDJ64923.1 - 0.03 14.4 0.1 0.03 14.4 0.1 2.5 3 0 0 3 3 3 0 Chalcone isomerase-like Med15 PF09606.10 CDJ64923.1 - 0.18 10.5 59.8 0.28 9.8 6.8 3.3 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal K_channel_TID PF07941.11 CDJ64925.1 - 0.0074 16.7 13.9 0.0074 16.7 13.9 3.2 3 0 0 3 3 3 1 Potassium channel Kv1.4 tandem inactivation domain PRTP PF01366.18 CDJ64925.1 - 0.14 10.2 1.0 0.17 9.9 1.0 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF4148 PF13663.6 CDJ64925.1 - 6.4 7.0 18.0 5.4 7.3 4.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) PepSY_2 PF13670.6 CDJ64925.1 - 9.3 6.3 20.2 4.4 7.4 1.3 2.6 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Ribosomal_60s PF00428.19 CDJ64926.1 - 8 7.1 66.2 0.83 10.3 4.5 4.2 4 0 0 4 4 4 0 60s Acidic ribosomal protein ASH PF15780.5 CDJ64929.1 - 9e-07 29.0 0.0 0.0021 18.2 0.0 2.9 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin WD40 PF00400.32 CDJ64931.1 - 7.3e-34 115.3 25.0 0.00021 22.0 1.7 11.2 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ64931.1 - 1.4e-17 63.7 0.0 0.0031 17.8 0.0 7.8 4 2 5 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ64931.1 - 4.6e-05 23.4 0.0 0.013 15.4 0.0 3.8 3 2 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 CDJ64931.1 - 0.00097 19.6 5.0 20 5.8 0.0 6.8 7 0 0 7 7 7 0 PQQ-like domain PD40 PF07676.12 CDJ64931.1 - 0.002 18.0 0.0 10 6.2 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CDJ64931.1 - 0.0044 16.0 0.1 8.5 5.2 0.0 4.2 4 1 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Reg_prop PF07494.11 CDJ64931.1 - 0.015 15.4 0.1 55 4.5 0.0 4.8 4 0 0 4 4 4 0 Two component regulator propeller Cytochrom_D1 PF02239.16 CDJ64931.1 - 0.1 11.1 0.0 5.9 5.3 0.0 2.7 3 0 0 3 3 3 0 Cytochrome D1 heme domain Nup160 PF11715.8 CDJ64931.1 - 0.11 11.2 0.2 7.9 5.0 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 NHL PF01436.21 CDJ64931.1 - 0.17 12.0 0.5 1.7 8.9 0.1 2.8 3 0 0 3 3 3 0 NHL repeat KASH_CCD PF14662.6 CDJ64932.1 - 0.0026 17.6 2.8 0.0037 17.1 2.8 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 CDJ64932.1 - 0.0027 18.0 7.5 0.004 17.4 7.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 CDJ64932.1 - 0.0045 17.0 3.9 0.027 14.5 2.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) MAD PF05557.13 CDJ64932.1 - 0.0049 15.3 2.7 0.0062 15.0 2.7 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Spectrin PF00435.21 CDJ64932.1 - 0.0065 16.9 5.7 0.074 13.5 5.7 2.1 1 1 0 1 1 1 1 Spectrin repeat Spc7 PF08317.11 CDJ64932.1 - 0.0067 15.3 4.4 0.0088 15.0 4.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.21 CDJ64932.1 - 0.0073 15.9 3.1 0.0089 15.6 3.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein TMF_DNA_bd PF12329.8 CDJ64932.1 - 0.0083 16.1 7.1 0.01 15.8 4.4 2.0 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.20 CDJ64932.1 - 0.012 15.5 2.4 1 9.4 2.6 2.3 2 1 0 2 2 2 0 Prefoldin subunit Exonuc_VII_L PF02601.15 CDJ64932.1 - 0.013 15.1 1.1 0.015 14.9 1.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sigma54_CBD PF04963.13 CDJ64932.1 - 0.013 15.4 3.3 1.8 8.4 3.3 2.0 1 1 0 1 1 1 0 Sigma-54 factor, core binding domain ADIP PF11559.8 CDJ64932.1 - 0.015 15.4 4.4 0.14 12.2 3.0 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HMMR_N PF15905.5 CDJ64932.1 - 0.019 14.5 2.9 0.023 14.2 2.9 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 CDJ64932.1 - 0.021 14.2 0.9 0.028 13.8 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ead_Ea22 PF13935.6 CDJ64932.1 - 0.027 15.1 0.8 0.033 14.9 0.8 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF3618 PF12277.8 CDJ64932.1 - 0.034 14.4 1.0 0.14 12.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) BST2 PF16716.5 CDJ64932.1 - 0.037 14.6 8.1 0.057 14.0 5.8 1.9 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 FliD_N PF02465.18 CDJ64932.1 - 0.046 14.4 2.6 0.38 11.5 2.6 2.2 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Med9 PF07544.13 CDJ64932.1 - 0.071 13.2 0.9 0.071 13.2 0.9 2.5 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Cob_adeno_trans PF01923.18 CDJ64932.1 - 0.078 13.1 0.3 0.1 12.7 0.3 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Snapin_Pallidin PF14712.6 CDJ64932.1 - 0.079 13.4 8.4 0.097 13.1 1.9 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Baculo_PEP_C PF04513.12 CDJ64932.1 - 0.081 13.0 3.9 0.29 11.2 3.9 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mating_N PF12731.7 CDJ64932.1 - 0.083 13.0 3.0 17 5.6 0.0 3.0 3 0 0 3 3 3 0 Mating-type protein beta 1 THDPS_N_2 PF14805.6 CDJ64932.1 - 0.089 13.0 1.0 1.1 9.6 0.2 2.4 1 1 1 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF948 PF06103.11 CDJ64932.1 - 0.1 12.9 0.6 0.18 12.1 0.3 1.5 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 CDJ64932.1 - 0.1 11.7 3.9 0.13 11.3 3.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 CDJ64932.1 - 0.12 12.7 5.2 6.5 7.1 0.1 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1690 PF07956.11 CDJ64932.1 - 0.15 12.5 5.0 0.24 11.8 4.3 1.6 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Ran-binding PF05508.11 CDJ64932.1 - 0.16 11.0 2.9 0.2 10.6 2.9 1.2 1 0 0 1 1 1 0 RanGTP-binding protein TMPIT PF07851.13 CDJ64932.1 - 0.16 11.2 2.3 0.19 10.9 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein APG6_N PF17675.1 CDJ64932.1 - 0.16 12.5 6.9 0.21 12.1 6.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 CDJ64932.1 - 0.19 12.3 3.6 0.39 11.3 3.6 1.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FUSC PF04632.12 CDJ64932.1 - 0.23 10.0 1.2 0.26 9.8 1.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family BRE1 PF08647.11 CDJ64932.1 - 0.3 11.2 6.3 0.71 10.0 1.7 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 CDJ64932.1 - 0.31 11.1 10.4 5.7 7.0 5.9 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 CDJ64932.1 - 0.35 10.1 6.3 0.22 10.8 4.2 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Fzo_mitofusin PF04799.13 CDJ64932.1 - 0.37 10.3 3.4 1.3 8.6 0.5 1.9 1 1 1 2 2 2 0 fzo-like conserved region Csm1_N PF18504.1 CDJ64932.1 - 0.53 10.7 4.8 15 6.0 1.6 2.7 1 1 1 3 3 2 0 Csm1 N-terminal domain FlaC_arch PF05377.11 CDJ64932.1 - 0.59 10.6 2.2 20 5.6 0.2 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 CDJ64932.1 - 0.65 10.5 5.4 0.64 10.5 2.8 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 KxDL PF10241.9 CDJ64932.1 - 0.69 10.2 5.7 0.78 10.1 3.3 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein Fib_alpha PF08702.10 CDJ64932.1 - 0.83 9.8 4.5 2.3 8.4 4.5 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 CDJ64932.1 - 0.87 10.1 4.9 24 5.5 1.8 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.11 CDJ64932.1 - 1.1 9.0 5.9 4.6 7.0 5.9 1.8 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) LPP PF04728.13 CDJ64932.1 - 1.3 9.5 6.1 9.6 6.7 0.2 2.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper SlyX PF04102.12 CDJ64932.1 - 3.1 8.5 11.9 1.1 9.9 1.1 2.9 1 1 2 3 3 3 0 SlyX DivIC PF04977.15 CDJ64932.1 - 6.7 6.6 10.8 6.4 6.6 1.4 2.9 1 1 2 3 3 3 0 Septum formation initiator Fez1 PF06818.15 CDJ64933.1 - 0.058 13.8 9.5 0.078 13.4 8.4 1.7 1 1 0 1 1 1 0 Fez1 TetR PF13972.6 CDJ64933.1 - 0.11 12.2 0.6 0.26 11.0 0.6 1.7 1 1 0 1 1 1 0 Bacterial transcriptional repressor Glyco_hydro_77 PF02446.17 CDJ64934.1 - 2e-51 175.3 0.2 6e-51 173.8 0.2 1.6 1 1 0 1 1 1 1 4-alpha-glucanotransferase Ribosomal_60s PF00428.19 CDJ64936.1 - 3.9e-23 81.9 11.9 5e-23 81.5 11.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2057 PF09829.9 CDJ64936.1 - 3.2 7.9 5.4 5 7.3 5.4 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) RskA PF10099.9 CDJ64938.1 - 1.1e-07 32.3 2.3 1.1e-07 32.3 2.3 5.9 2 1 2 4 4 4 2 Anti-sigma-K factor rskA zf_CCCH_4 PF18345.1 CDJ64941.1 - 7.6e-19 67.1 23.1 2e-06 27.7 1.5 4.5 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH PF00642.24 CDJ64941.1 - 2.3e-17 62.4 20.8 8.2e-06 25.6 0.3 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ64941.1 - 9.9e-14 50.8 22.5 1.5e-05 24.7 1.4 4.3 4 0 0 4 4 4 4 CCCH-type zinc finger RskA PF10099.9 CDJ64941.1 - 1.3e-08 35.4 0.2 1.3e-08 35.4 0.2 7.1 2 2 4 6 6 6 1 Anti-sigma-K factor rskA zf-CCCH_2 PF14608.6 CDJ64941.1 - 1.5e-07 31.6 26.4 0.0025 18.2 2.2 4.3 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CDJ64941.1 - 0.012 16.2 9.8 0.035 14.8 1.1 8.6 4 2 5 9 9 9 0 Torus domain Pkinase PF00069.25 CDJ64942.1 - 3.7e-15 56.0 0.0 3.7e-15 56.0 0.0 3.0 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ64942.1 - 1.5e-06 27.7 0.0 1.5e-06 27.7 0.0 2.8 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2341 PF10102.9 CDJ64943.1 - 0.14 12.7 14.1 3.2 8.4 1.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF2341) RVT_1 PF00078.27 CDJ64945.1 - 6.7e-20 71.6 0.1 1.3e-19 70.7 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ64946.1 - 2.9e-16 59.3 2.3 4.9e-16 58.6 1.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CDJ64946.1 - 3.6e-12 46.5 0.0 1.6e-11 44.4 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ64946.1 - 0.00016 21.8 0.4 0.00033 20.8 0.4 1.5 1 0 0 1 1 1 1 H2C2 zinc finger DREPP PF05558.12 CDJ64947.1 - 0.064 13.1 0.6 0.12 12.3 0.6 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide DUF1180 PF06679.12 CDJ64947.1 - 0.1 13.0 0.8 0.42 11.0 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) ACDC PF14733.6 CDJ64948.1 - 2.7e-17 62.9 0.1 7.3e-17 61.5 0.1 1.7 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ64948.1 - 1.4e-09 38.0 0.2 1.4e-09 38.0 0.2 2.3 2 0 0 2 2 2 1 AP2 domain Activator_LAG-3 PF11498.8 CDJ64948.1 - 1.4 7.8 25.7 0.081 11.9 17.9 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 IFP_35_N PF07334.13 CDJ64950.1 - 0.11 12.6 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus AAA_33 PF13671.6 CDJ64951.1 - 0.13 12.4 0.1 0.13 12.4 0.1 4.6 5 1 0 5 5 5 0 AAA domain RNA_ligase PF09414.10 CDJ64951.1 - 0.14 12.4 0.0 17 5.7 0.0 2.6 2 0 0 2 2 2 0 RNA ligase RPN2_C PF18004.1 CDJ64951.1 - 4.7 7.1 10.3 4.7 7.1 1.6 3.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Hydrolase_3 PF08282.12 CDJ64954.1 - 4.1e-35 121.7 0.0 1.7e-19 70.6 0.0 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ64954.1 - 4.6e-10 39.5 0.0 0.00017 21.2 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CDJ64954.1 - 1.4e-08 35.3 0.1 0.099 12.9 0.0 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ64954.1 - 0.0006 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 CDJ64954.1 - 0.0096 15.5 0.0 0.095 12.3 0.0 2.0 1 1 1 2 2 2 2 HAD superfamily, subfamily IIIB (Acid phosphatase) ATPgrasp_N PF18130.1 CDJ64954.1 - 0.013 16.1 0.0 1.2 9.8 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp N-terminal domain HAD PF12710.7 CDJ64954.1 - 0.08 13.3 0.0 20 5.5 0.0 3.4 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase zf-B_box PF00643.24 CDJ64955.1 - 9.5e-11 41.7 17.7 4.4e-06 26.8 5.3 3.0 3 0 0 3 3 3 2 B-box zinc finger DUF3135 PF11333.8 CDJ64955.1 - 0.0069 16.6 0.3 0.0069 16.6 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3135) PARP PF00644.20 CDJ64955.1 - 0.0092 15.6 0.6 0.049 13.2 0.2 2.3 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain DUF4407 PF14362.6 CDJ64959.1 - 8.3 5.7 27.9 0.037 13.4 5.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF45 PF01863.17 CDJ64959.1 - 9.5 6.2 11.9 1.1 9.3 5.5 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 FAM60A PF15396.6 CDJ64959.1 - 9.7 6.1 10.4 5.9 6.8 3.8 2.2 2 0 0 2 2 2 0 Protein Family FAM60A RNB PF00773.19 CDJ64960.1 - 8.4e-15 54.9 5.5 7.4e-14 51.8 0.4 2.4 2 1 0 2 2 2 2 RNB domain DUF2722 PF10846.8 CDJ64960.1 - 0.006 15.6 1.0 0.0088 15.0 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Mvb12 PF09452.10 CDJ64960.1 - 0.17 12.3 0.6 0.39 11.2 0.0 1.8 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Imm40 PF15569.6 CDJ64960.1 - 0.19 11.9 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 40 FAM104 PF15434.6 CDJ64960.1 - 0.22 12.1 4.8 1.3 9.6 0.4 3.3 3 0 0 3 3 3 0 Family 104 Spt20 PF12090.8 CDJ64960.1 - 0.3 10.7 11.0 0.53 9.9 11.0 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ64960.1 - 1.2 9.1 29.7 0.0075 16.3 14.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DivIC PF04977.15 CDJ64960.1 - 1.3 8.8 8.2 2.7 7.8 8.2 1.4 1 0 0 1 1 1 0 Septum formation initiator GET2 PF08690.10 CDJ64960.1 - 4.1 7.0 8.7 10 5.7 3.6 2.4 2 0 0 2 2 2 0 GET complex subunit GET2 SR-25 PF10500.9 CDJ64961.1 - 0.033 13.8 18.7 0.039 13.6 18.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NPR3 PF03666.13 CDJ64961.1 - 0.086 11.6 1.4 0.086 11.6 1.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM199X PF15814.5 CDJ64961.1 - 2.9 6.9 11.0 3 6.8 11.0 1.0 1 0 0 1 1 1 0 Protein family FAM199X Apt1 PF10351.9 CDJ64961.1 - 4.1 6.2 6.6 4.2 6.1 6.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF755 PF05501.11 CDJ64961.1 - 4.4 7.6 23.3 6.4 7.1 23.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RAP1 PF07218.11 CDJ64961.1 - 4.5 5.4 12.9 4.9 5.3 12.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 CDJ64961.1 - 4.8 5.6 5.9 4.9 5.6 5.9 1.1 1 0 0 1 1 1 0 Macoilin family Serglycin PF04360.12 CDJ64961.1 - 6.8 6.6 8.9 8.9 6.3 8.9 1.2 1 0 0 1 1 1 0 Serglycin AF-4 PF05110.13 CDJ64961.1 - 7 4.6 21.9 7.8 4.4 21.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein 14-3-3 PF00244.20 CDJ64962.1 - 2.7e-06 27.1 2.5 2.7e-06 27.1 2.5 2.7 3 1 0 3 3 3 1 14-3-3 protein DUF2722 PF10846.8 CDJ64962.1 - 0.0038 16.2 1.8 0.0038 16.2 1.8 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ64962.1 - 0.19 11.3 43.5 0.15 11.6 7.7 3.2 3 0 0 3 3 3 0 Spt20 family DXP_synthase_N PF13292.6 CDJ64962.1 - 0.35 10.0 1.9 0.42 9.8 0.1 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase RskA PF10099.9 CDJ64962.1 - 7.8 6.8 29.0 0.053 13.8 9.4 3.3 2 1 2 4 4 4 0 Anti-sigma-K factor rskA Med15 PF09606.10 CDJ64962.1 - 7.9 5.0 45.8 2.5 6.7 5.1 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.14 CDJ64963.1 - 0.67 9.9 20.3 0.051 13.5 12.7 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Tmemb_cc2 PF10267.9 CDJ64963.1 - 2.7 7.1 21.8 0.41 9.7 16.8 1.8 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Pkinase PF00069.25 CDJ64964.1 - 1.3e-19 70.6 0.0 6.7e-16 58.4 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain Kinase-like PF14531.6 CDJ64964.1 - 3.8e-16 59.2 0.0 6.7e-15 55.1 0.0 2.3 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ64964.1 - 2.9e-05 23.5 0.0 0.00016 21.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase ACBP PF00887.19 CDJ64965.1 - 3.2e-24 84.9 0.1 5.6e-24 84.2 0.1 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 CDJ64965.1 - 3.3e-14 52.8 0.1 3.2e-07 30.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ64965.1 - 2.2e-11 44.2 0.1 5e-11 43.0 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ64965.1 - 3.1e-11 43.2 0.1 3.1e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CDJ64965.1 - 5.4e-11 42.8 0.2 2.8e-07 30.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ64965.1 - 9.1e-09 34.9 0.1 0.0015 18.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Virul_fac_BrkB PF03631.15 CDJ64967.1 - 4.7 6.7 9.7 0.4 10.3 3.8 2.1 3 0 0 3 3 3 0 Virulence factor BrkB PseudoU_synth_2 PF00849.22 CDJ64969.1 - 3.6e-25 88.9 0.0 6.1e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase rve PF00665.26 CDJ64970.1 - 3.3e-14 53.1 0.0 7.6e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 CDJ64970.1 - 0.0049 16.9 1.9 0.0099 15.9 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 CDJ64970.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L33 PF00471.20 CDJ64971.1 - 1.9e-08 34.6 0.5 5.9e-08 33.0 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L33 Fes1 PF08609.10 CDJ64974.1 - 0.03 15.2 0.2 1.2 10.1 0.0 3.1 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 Diphthami_syn_2 PF01902.17 CDJ64975.1 - 1.2e-20 73.9 0.0 2.6e-20 72.9 0.0 1.6 1 1 0 1 1 1 1 Diphthamide synthase PI3K_C2 PF00792.24 CDJ64975.1 - 0.18 11.7 0.0 0.49 10.3 0.0 1.7 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 AAA PF00004.29 CDJ64976.1 - 1.2e-28 100.2 0.1 2.7e-28 99.0 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ64976.1 - 7.5e-08 32.1 0.0 2.4e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CDJ64976.1 - 1.4e-06 28.2 3.9 9.7e-06 25.5 0.3 2.8 2 1 1 3 3 3 2 Vps4 C terminal oligomerisation domain DnaJ PF00226.31 CDJ64977.1 - 7.3e-19 67.7 9.2 9.3e-19 67.3 1.1 3.5 2 2 0 2 2 2 1 DnaJ domain TINF2_N PF14973.6 CDJ64977.1 - 1.3 9.4 3.9 2.5 8.4 1.0 2.3 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus GYF PF02213.16 CDJ64978.1 - 2.3e-09 36.7 0.0 5.2e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 GYF domain TniQ PF06527.11 CDJ64978.1 - 0.5 11.1 4.6 1.7 9.4 4.6 2.0 1 1 0 1 1 1 0 TniQ Pkinase PF00069.25 CDJ64979.1 - 6.4e-18 65.1 0.0 2.3e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ64979.1 - 2.2e-10 40.3 0.0 3.6e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ64979.1 - 1.2e-07 31.3 0.4 4.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like DUF4259 PF14078.6 CDJ64979.1 - 0.31 11.8 3.2 0.64 10.8 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) MOZ_SAS PF01853.18 CDJ64980.1 - 1.8e-52 177.6 0.1 5.9e-37 127.0 0.4 2.2 1 1 1 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 CDJ64980.1 - 6.4e-20 70.5 1.1 1.3e-19 69.5 1.1 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDJ64980.1 - 2.6e-09 36.8 0.0 5.9e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain DUF4590 PF15257.6 CDJ64980.1 - 0.0018 18.2 2.4 0.006 16.5 2.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4590) LEA_3 PF03242.13 CDJ64980.1 - 0.1 13.3 0.0 0.1 13.3 0.0 3.0 3 0 0 3 3 3 0 Late embryogenesis abundant protein Ribosomal_S16 PF00886.19 CDJ64981.1 - 1.1e-16 60.6 0.0 1.8e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Kinesin_assoc PF16183.5 CDJ64982.1 - 0.053 13.7 0.2 0.053 13.7 0.2 3.9 4 1 1 5 5 5 0 Kinesin-associated Pkinase PF00069.25 CDJ64983.1 - 5e-18 65.4 0.0 2.2e-15 56.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 CDJ64983.1 - 6.7e-11 42.0 0.0 4.4e-10 39.3 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ64983.1 - 4e-07 29.6 0.0 9e-07 28.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase MCM PF00493.23 CDJ64984.1 - 6.8e-76 254.3 0.0 3.6e-50 170.2 0.1 3.3 2 1 1 3 3 3 3 MCM P-loop domain MCM_OB PF17207.3 CDJ64984.1 - 1.9e-30 105.3 0.1 4.6e-30 104.1 0.1 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDJ64984.1 - 5.1e-25 87.7 0.6 3.5e-24 85.0 0.4 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM6_C PF18263.1 CDJ64984.1 - 1.2e-08 35.1 0.1 5.5e-08 33.0 0.1 2.2 1 1 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 CDJ64984.1 - 1.2e-06 29.0 0.0 1.4e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 CDJ64984.1 - 0.18 11.8 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Clathrin_lg_ch PF01086.17 CDJ64985.1 - 4.7e-08 33.4 17.6 4.7e-08 33.4 17.6 2.3 2 1 0 2 2 2 1 Clathrin light chain DUF755 PF05501.11 CDJ64985.1 - 0.019 15.3 13.6 0.019 15.3 13.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Esterase PF00756.20 CDJ64985.1 - 0.021 14.4 2.6 0.26 10.9 0.8 2.1 2 0 0 2 2 2 0 Putative esterase LMBR1 PF04791.16 CDJ64985.1 - 0.053 12.4 0.2 0.066 12.1 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Vir_act_alpha_C PF10400.9 CDJ64985.1 - 0.058 14.1 2.0 0.058 14.1 2.0 3.4 2 1 0 3 3 3 0 Virulence activator alpha C-term AAA_11 PF13086.6 CDJ64985.1 - 4.5 7.0 16.8 1.4 8.6 7.7 2.2 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 CDJ64985.1 - 5.1 6.6 22.7 5.3 6.5 12.6 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit tRNA-synt_2 PF00152.20 CDJ64986.1 - 1.1e-38 133.1 0.0 2.3e-35 122.2 0.0 3.2 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CDJ64986.1 - 0.0016 18.0 0.0 0.68 9.4 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 CDJ64986.1 - 0.0045 17.0 0.0 0.035 14.1 0.0 2.1 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RskA PF10099.9 CDJ64986.1 - 0.0067 16.7 2.3 0.0067 16.7 2.3 9.1 3 2 3 6 6 6 2 Anti-sigma-K factor rskA BPL_C PF02237.17 CDJ64986.1 - 0.13 12.1 0.0 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain DUF3446 PF11928.8 CDJ64987.1 - 0.0012 19.0 22.0 0.023 15.0 3.3 3.6 3 0 0 3 3 3 3 Early growth response N-terminal domain Antiterm PF03589.13 CDJ64987.1 - 0.054 13.8 0.0 0.41 11.0 0.0 2.4 2 0 0 2 2 2 0 Antitermination protein Peripla_BP_2 PF01497.18 CDJ64987.1 - 0.069 12.7 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Periplasmic binding protein RPAP3_C PF13877.6 CDJ64987.1 - 0.13 12.8 0.5 0.85 10.2 0.3 2.4 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 Pheromone PF08015.11 CDJ64987.1 - 0.71 11.0 12.4 8.1 7.6 0.8 3.8 3 0 0 3 3 3 0 Fungal mating-type pheromone ERCC4 PF02732.15 CDJ64988.1 - 1.6e-12 47.9 0.0 1.6e-12 47.9 0.0 3.2 4 0 0 4 4 4 1 ERCC4 domain DUF2722 PF10846.8 CDJ64988.1 - 0.048 12.6 0.1 0.048 12.6 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ64988.1 - 0.17 10.8 38.1 0.4 9.6 0.5 3.9 3 0 0 3 3 3 0 Transcriptional activator LAG-3 GCFC PF07842.12 CDJ64989.1 - 4e-33 115.2 10.7 4e-33 115.2 10.7 2.1 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 CDJ64989.1 - 1.7e-08 34.2 0.9 4.5e-08 32.9 0.9 1.7 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 CDJ64989.1 - 0.00043 20.6 7.9 0.00043 20.6 7.9 5.6 2 2 4 6 6 6 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 CDJ64989.1 - 0.066 13.3 0.1 0.35 11.0 0.1 2.4 1 0 0 1 1 1 0 G-patch domain Peptidase_S49_N PF08496.10 CDJ64990.1 - 7.7 6.6 6.9 11 6.1 3.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MRP-S31 PF15433.6 CDJ64990.1 - 9.5 5.8 21.0 13 5.3 20.2 1.6 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 IQ PF00612.27 CDJ64992.1 - 0.0032 17.1 8.3 0.027 14.3 0.6 3.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF4179 PF13786.6 CDJ64992.1 - 0.034 14.6 4.6 3.3 8.2 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) MDM31_MDM32 PF08118.11 CDJ64992.1 - 2 7.0 22.5 3.5 6.2 0.8 2.3 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins TatD_DNase PF01026.21 CDJ64993.1 - 2.8e-32 112.1 0.2 7.2e-31 107.5 0.2 2.2 1 1 0 1 1 1 1 TatD related DNase SUIM_assoc PF16619.5 CDJ64993.1 - 0.0097 15.9 14.7 0.041 13.9 5.8 3.6 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ64993.1 - 0.069 12.7 16.3 0.18 11.4 3.5 3.0 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 CDJ64993.1 - 0.28 10.9 0.0 0.28 10.9 0.0 2.1 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Secretin_N_2 PF07655.13 CDJ64993.1 - 1 10.0 19.8 1.9 9.1 3.8 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain baeRF_family7 PF18849.1 CDJ64994.1 - 0.042 14.0 2.4 1.8 8.8 2.1 2.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 DUF155 PF02582.14 CDJ64994.1 - 0.44 10.6 2.1 1.1 9.3 0.5 2.4 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 NTF2 PF02136.20 CDJ64997.1 - 4.6e-16 59.5 0.0 4.6e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Borrelia_P83 PF05262.11 CDJ64997.1 - 0.47 8.9 18.4 0.84 8.1 18.4 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_23 PF13476.6 CDJ64997.1 - 7.4 7.0 19.5 16 5.9 19.5 1.5 1 0 0 1 1 1 0 AAA domain AP2 PF00847.20 CDJ64998.1 - 4.2e-09 36.5 0.2 8.5e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 AP2 domain C2 PF00168.30 CDJ64999.1 - 1.1e-33 115.6 0.2 1.4e-06 28.5 0.0 6.5 6 0 0 6 6 6 6 C2 domain Ferlin_C PF16165.5 CDJ64999.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Ferlin C-terminus Exonuc_VII_L PF02601.15 CDJ65000.1 - 0.032 13.8 0.9 0.045 13.3 0.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ERM PF00769.19 CDJ65000.1 - 0.042 13.6 13.7 0.074 12.9 13.7 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHODB_Fe-S_bind PF10418.9 CDJ65000.1 - 0.94 9.3 6.6 2.3 8.1 6.6 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B ADIP PF11559.8 CDJ65000.1 - 5.4 7.1 13.7 9.6 6.3 13.7 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tho2 PF11262.8 CDJ65000.1 - 7.3 5.7 5.3 11 5.1 5.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Pyr_redox_2 PF07992.14 CDJ65002.1 - 8.5e-73 245.1 2.0 1.3e-72 244.6 2.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ65002.1 - 1e-35 122.3 0.1 3.5e-35 120.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ65002.1 - 1.2e-23 83.4 5.2 1.1e-20 73.9 0.5 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ65002.1 - 5e-11 42.4 1.4 1.1e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ65002.1 - 3.4e-10 39.9 0.2 3.4e-10 39.9 0.2 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CDJ65002.1 - 5.7e-08 31.9 4.9 0.00039 19.2 0.1 3.9 3 1 1 4 4 4 2 HI0933-like protein GIDA PF01134.22 CDJ65002.1 - 2.9e-07 29.9 7.0 8.2e-07 28.4 2.9 2.8 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CDJ65002.1 - 1.4e-06 27.7 3.7 1.4e-06 27.7 3.7 3.1 3 1 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 CDJ65002.1 - 5.9e-06 25.8 9.3 0.09 12.0 0.0 3.1 2 1 1 3 3 3 3 FAD binding domain K_oxygenase PF13434.6 CDJ65002.1 - 7.1e-06 25.4 0.2 0.054 12.6 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 CDJ65002.1 - 3.1e-05 23.4 2.7 0.01 15.1 0.2 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CDJ65002.1 - 3.5e-05 23.6 9.9 0.058 13.0 0.0 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ65002.1 - 7.6e-05 22.9 7.9 0.00065 19.9 1.5 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CDJ65002.1 - 0.00024 20.4 2.1 0.0007 18.9 0.1 2.6 3 0 0 3 3 3 1 Thi4 family 3HCDH_N PF02737.18 CDJ65002.1 - 0.057 13.3 0.1 0.057 13.3 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 CDJ65002.1 - 0.086 13.3 0.0 13 6.4 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 CDJ65002.1 - 0.31 10.0 3.1 1.3 8.0 0.1 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Peptidase_S9 PF00326.21 CDJ65003.1 - 4.4e-08 32.9 0.2 0.0028 17.1 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ65003.1 - 5.4e-07 29.5 0.4 8.4e-06 25.6 0.3 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CDJ65003.1 - 6.7e-07 29.2 0.1 2.7e-06 27.2 0.1 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 CDJ65003.1 - 6.9e-05 22.2 0.1 0.0051 16.1 0.2 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 PhoPQ_related PF10142.9 CDJ65003.1 - 0.00059 18.6 0.0 0.00099 17.9 0.0 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein VirJ PF06057.11 CDJ65003.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_3 PF07859.13 CDJ65003.1 - 0.022 14.6 0.9 0.054 13.3 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9_N PF02897.15 CDJ65004.1 - 1.7e-106 356.5 0.1 2.4e-106 356.0 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CDJ65004.1 - 1.6e-57 194.4 0.0 3e-57 193.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4227 PF14004.6 CDJ65004.1 - 0.043 13.8 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) Abhydrolase_3 PF07859.13 CDJ65004.1 - 0.057 13.3 0.1 0.29 11.0 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 CDJ65004.1 - 0.076 12.6 0.1 1.1 8.9 0.0 2.4 2 1 0 3 3 3 0 alpha/beta hydrolase fold BAAT_C PF08840.11 CDJ65004.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal TPR_MLP1_2 PF07926.12 CDJ65007.1 - 0.00015 21.8 14.0 0.00015 21.8 14.0 6.6 3 1 3 6 6 6 1 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 CDJ65007.1 - 0.012 15.8 7.8 0.012 15.8 7.8 7.8 4 2 4 8 8 8 0 TATA element modulatory factor 1 TATA binding HalX PF08663.10 CDJ65007.1 - 0.027 14.8 0.2 0.024 14.9 7.4 9.8 4 4 5 10 10 10 0 HalX domain GAS PF13851.6 CDJ65007.1 - 0.028 13.8 80.7 0.013 14.8 20.4 5.0 4 1 0 4 4 4 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 CDJ65007.1 - 0.23 11.5 24.5 0.2 11.7 1.2 4.6 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 CDJ65007.1 - 3.2 8.3 33.7 11 6.5 0.4 8.0 6 2 1 7 7 7 0 Nucleopolyhedrovirus P10 protein EELM2 PF15863.5 CDJ65008.1 - 7.2e-63 211.8 0.0 1.2e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 Extended EGL-27 and MTA1 homology domain Pre-PUA PF17832.1 CDJ65009.1 - 1e-26 93.5 0.2 1.5e-26 92.9 0.2 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CDJ65009.1 - 1.4e-14 53.8 0.0 1.9e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 CDJ65009.1 - 0.03 14.6 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) S10_plectin PF03501.15 CDJ65010.1 - 2e-41 140.0 0.6 2.5e-41 139.7 0.6 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF2250 PF10007.9 CDJ65010.1 - 0.11 12.6 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) zf-CCCH PF00642.24 CDJ65011.1 - 2.6e-09 36.7 19.7 5.1e-05 23.1 1.7 3.5 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ65011.1 - 0.00033 20.4 3.6 0.00033 20.4 3.6 3.7 3 1 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDJ65011.1 - 0.00054 19.9 5.3 0.00054 19.9 5.3 4.5 5 0 0 5 5 5 1 Zinc finger domain zf-CCCH_3 PF15663.5 CDJ65011.1 - 0.00074 19.7 4.4 0.0023 18.1 1.0 2.2 2 0 0 2 2 2 1 Zinc-finger containing family Torus PF16131.5 CDJ65011.1 - 0.0034 18.1 11.7 0.033 14.9 2.6 3.0 1 1 2 3 3 3 2 Torus domain zf-C3H1 PF10650.9 CDJ65011.1 - 0.012 15.3 6.4 5.2 6.9 0.2 3.3 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 CDJ65011.1 - 0.089 13.3 19.7 0.84 10.2 1.2 3.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Aldedh PF00171.22 CDJ65012.1 - 0.0006 18.4 1.3 0.0022 16.6 0.0 2.3 3 0 0 3 3 3 1 Aldehyde dehydrogenase family PCRF PF03462.18 CDJ65013.1 - 6.2e-32 111.0 4.2 6.2e-32 111.0 4.2 2.4 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 CDJ65013.1 - 2.3e-28 98.4 1.9 2.3e-28 98.4 1.9 2.8 3 0 0 3 3 3 1 RF-1 domain Spt20 PF12090.8 CDJ65013.1 - 0.7 9.5 9.9 0.28 10.7 2.1 2.3 2 0 0 2 2 2 0 Spt20 family CheY-binding PF09078.11 CDJ65019.1 - 0.038 14.1 1.0 3.1 8.0 0.1 2.8 2 0 0 2 2 2 0 CheY binding PPIP5K2_N PF18086.1 CDJ65019.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Prefoldin_2 PF01920.20 CDJ65020.1 - 0.0033 17.4 0.0 0.0038 17.2 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit RbpA PF13397.6 CDJ65021.1 - 0.017 15.7 0.7 0.017 15.7 0.7 2.1 2 0 0 2 2 2 0 RNA polymerase-binding protein Takusan PF04822.13 CDJ65022.1 - 0.015 15.2 0.6 0.048 13.5 0.6 1.9 1 0 0 1 1 1 0 Takusan US6 PF17616.2 CDJ65023.1 - 0.29 11.1 1.3 0.42 10.5 1.3 1.1 1 0 0 1 1 1 0 Viral unique short region 6 Adeno_E3_CR2 PF02439.15 CDJ65023.1 - 1.4 8.7 3.9 14 5.6 0.0 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 IRK_C PF17655.1 CDJ65024.1 - 2.2e-06 27.4 0.0 4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 CDJ65024.1 - 0.014 15.4 0.4 0.027 14.4 0.4 1.4 1 0 0 1 1 1 0 Ion channel IRK PF01007.20 CDJ65024.1 - 0.045 13.5 0.5 0.099 12.5 0.5 1.6 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain GAS PF13851.6 CDJ65028.1 - 0.0045 16.4 7.6 0.0066 15.8 7.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Filament PF00038.21 CDJ65028.1 - 0.018 14.6 4.6 0.022 14.3 4.6 1.0 1 0 0 1 1 1 0 Intermediate filament protein DUF4238 PF14022.6 CDJ65028.1 - 0.07 12.6 0.8 0.068 12.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) FAM76 PF16046.5 CDJ65028.1 - 0.099 12.0 6.5 0.12 11.8 6.5 1.0 1 0 0 1 1 1 0 FAM76 protein YabA PF06156.13 CDJ65028.1 - 0.41 11.3 4.6 1.5 9.5 4.6 1.8 1 1 0 1 1 1 0 Initiation control protein YabA BST2 PF16716.5 CDJ65028.1 - 1.1 9.9 7.6 3.2 8.4 1.1 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Csm1_N PF18504.1 CDJ65028.1 - 2.8 8.4 7.8 2.1 8.7 4.8 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain IFP_35_N PF07334.13 CDJ65028.1 - 3 8.0 11.9 7.5 6.7 0.4 3.0 1 1 2 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus UPF0242 PF06785.11 CDJ65029.1 - 0.075 13.1 12.6 0.1 12.7 12.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PLAC9 PF15205.6 CDJ65029.1 - 0.13 12.7 1.4 0.35 11.3 0.3 2.1 2 0 0 2 2 2 0 Placenta-specific protein 9 DUF4790 PF16037.5 CDJ65029.1 - 0.85 10.1 5.1 2.1 8.9 0.7 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4790) APG6_N PF17675.1 CDJ65029.1 - 1.1 9.8 20.9 6 7.4 20.9 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region EzrA PF06160.12 CDJ65030.1 - 0.0008 17.7 30.9 0.001 17.4 30.9 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF3552 PF12072.8 CDJ65030.1 - 0.012 15.0 27.3 0.012 15.0 27.3 2.4 1 1 0 2 2 1 0 Domain of unknown function (DUF3552) DHR10 PF18595.1 CDJ65030.1 - 0.017 15.2 23.6 0.017 15.2 23.6 3.7 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain Hemagglutinin PF00509.18 CDJ65030.1 - 0.7 8.2 6.5 0.27 9.6 4.1 1.4 1 1 0 1 1 1 0 Haemagglutinin IFT57 PF10498.9 CDJ65030.1 - 0.84 8.5 32.7 1.8 7.5 32.7 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 GAS PF13851.6 CDJ65030.1 - 0.94 8.8 44.0 6.5 6.0 22.9 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 CDJ65030.1 - 1.5 9.2 38.6 7 7.0 12.1 2.1 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 CDJ65030.1 - 1.7 7.4 45.4 0.28 10.0 30.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Ribonucleas_3_2 PF11469.8 CDJ65030.1 - 1.8 9.0 6.0 13 6.3 0.5 2.4 1 1 0 2 2 2 0 Ribonuclease III ADIP PF11559.8 CDJ65030.1 - 2.7 8.1 48.1 3.4 7.7 17.3 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Leu_zip PF15294.6 CDJ65030.1 - 3 7.3 32.2 2.1 7.8 30.0 1.6 1 1 1 2 2 2 0 Leucine zipper DUF1664 PF07889.12 CDJ65030.1 - 5.1 7.2 24.9 5.8 7.0 12.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 CDJ65030.1 - 5.5 7.8 25.1 0.5 11.1 8.0 3.1 1 1 2 3 3 3 0 Occludin homology domain Rrn6 PF10214.9 CDJ65030.1 - 6.1 5.2 23.3 8.3 4.8 23.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor ATG16 PF08614.11 CDJ65030.1 - 7 6.8 48.2 3.6 7.8 29.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 CDJ65030.1 - 7 7.2 54.9 2.5 8.7 27.3 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region RRM_1 PF00076.22 CDJ65032.1 - 1.6e-28 98.3 0.0 2.6e-17 62.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ65032.1 - 1.4e-05 25.1 0.1 6.9e-05 22.9 0.1 2.2 2 1 0 2 2 2 1 RNA recognition motif Pkinase PF00069.25 CDJ65033.1 - 2.8e-52 177.7 0.0 5.1e-51 173.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65033.1 - 2.9e-37 128.4 0.0 3.9e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ65033.1 - 2e-08 33.9 0.0 3.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ65033.1 - 1.2e-05 24.4 0.6 1.5e-05 24.0 0.6 1.3 1 1 0 1 1 1 1 Fungal protein kinase Dynein_C PF18199.1 CDJ65034.1 - 1.5e-10 40.8 0.3 1.6e-10 40.7 0.3 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 CDJ65035.1 - 1.2e-56 192.2 2.9 2e-56 191.5 2.9 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 CDJ65035.1 - 1.5e-51 175.3 0.2 8.8e-51 172.7 0.0 2.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ65035.1 - 1.6e-46 158.2 0.0 1.6e-46 158.2 0.0 2.5 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDJ65035.1 - 4.7e-29 101.2 0.0 7.9e-18 64.6 0.0 3.7 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA_6 PF12774.7 CDJ65035.1 - 2e-23 82.9 2.9 1.9e-21 76.4 0.1 3.3 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 CDJ65035.1 - 1.7e-18 66.9 0.0 5e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ65035.1 - 1.5e-06 28.3 0.0 8e-05 22.7 0.0 3.5 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain DUF812 PF05667.11 CDJ65035.1 - 0.00026 20.0 9.0 0.0055 15.7 0.8 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF812) AAA_5 PF07728.14 CDJ65035.1 - 0.0013 18.8 1.7 0.87 9.6 0.0 4.4 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CDJ65035.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA+ lid domain AAA_22 PF13401.6 CDJ65035.1 - 0.019 15.2 5.3 4.8 7.5 0.0 4.4 3 1 1 4 4 4 0 AAA domain Mg_chelatase PF01078.21 CDJ65035.1 - 0.059 12.8 1.7 8.4 5.7 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI DUF4407 PF14362.6 CDJ65035.1 - 0.12 11.7 17.8 0.017 14.5 4.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PRK PF00485.18 CDJ65035.1 - 0.19 11.5 0.8 1.2 8.9 0.2 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF4795 PF16043.5 CDJ65035.1 - 0.99 9.0 13.4 0.33 10.5 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) YkyA PF10368.9 CDJ65035.1 - 1.6 8.3 14.1 4 7.1 6.6 2.5 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein AAA_16 PF13191.6 CDJ65035.1 - 1.9 8.8 20.1 0.36 11.2 0.1 5.9 5 2 1 6 6 6 0 AAA ATPase domain AAA_23 PF13476.6 CDJ65035.1 - 3 8.3 15.0 8.7 6.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain Spc7 PF08317.11 CDJ65035.1 - 4.4 6.1 26.6 1.9 7.3 7.6 2.7 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_6 PF12774.7 CDJ65036.1 - 3.2e-90 302.4 0.0 5.8e-90 301.6 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ65036.1 - 2.8e-82 276.9 2.2 2.8e-82 276.9 2.2 2.3 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 CDJ65036.1 - 0.0011 19.0 0.1 0.018 15.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) SNAP PF14938.6 CDJ65036.1 - 0.0011 18.5 0.1 0.0032 17.0 0.1 1.8 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF4510 PF14971.6 CDJ65036.1 - 0.0088 16.4 4.0 0.0088 16.4 4.0 4.5 4 1 1 5 5 5 1 Domain of unknown function (DUF4510) eIF3m_C_helix PF18005.1 CDJ65036.1 - 0.012 15.3 3.5 0.24 11.1 0.4 2.9 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix AAA PF00004.29 CDJ65036.1 - 0.023 15.1 0.0 0.08 13.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sec34 PF04136.15 CDJ65036.1 - 0.54 10.1 4.7 1.8 8.4 0.3 3.9 3 1 1 4 4 4 0 Sec34-like family HsbA PF12296.8 CDJ65036.1 - 0.54 10.7 3.2 11 6.5 1.2 3.8 5 0 0 5 5 4 0 Hydrophobic surface binding protein A Cytochrom_B562 PF07361.11 CDJ65036.1 - 0.89 10.2 3.9 5 7.8 0.3 3.4 2 0 0 2 2 2 0 Cytochrome b562 RecC_C PF17946.1 CDJ65036.1 - 6.6 6.5 12.2 0.039 13.8 0.9 2.8 3 0 0 3 3 3 0 RecC C-terminal domain Baculo_PEP_C PF04513.12 CDJ65036.1 - 7.8 6.5 9.1 34 4.5 0.2 4.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YfkB PF08756.10 CDJ65038.1 - 0.12 12.2 0.0 0.38 10.5 0.0 1.9 1 0 0 1 1 1 0 YfkB-like domain DUF4148 PF13663.6 CDJ65039.1 - 0.92 9.7 16.2 0.22 11.7 5.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Kin17_mid PF10357.9 CDJ65042.1 - 4e-42 143.1 2.8 9.9e-42 141.8 2.8 1.7 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 CDJ65042.1 - 4.5e-19 68.3 1.7 1.1e-18 67.0 1.7 1.7 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 CDJ65042.1 - 0.0064 16.8 4.0 0.018 15.4 4.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ65042.1 - 0.29 11.5 7.3 0.13 12.6 4.2 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rick_17kDa_Anti PF05433.15 CDJ65044.1 - 0.069 13.0 0.4 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Clat_adaptor_s PF01217.20 CDJ65045.1 - 2.7e-09 37.1 0.0 5.7e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Hydrolase_4 PF12146.8 CDJ65046.1 - 7.2e-22 77.8 2.7 2.9e-21 75.8 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 DUF726 PF05277.12 CDJ65046.1 - 0.018 14.0 0.1 0.018 14.0 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.20 CDJ65046.1 - 0.088 12.4 0.0 0.24 11.0 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2457 PF10446.9 CDJ65049.1 - 0.065 12.4 23.1 0.68 9.0 15.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TFIIA PF03153.13 CDJ65049.1 - 0.087 12.8 31.5 0.11 12.4 31.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 CDJ65049.1 - 0.27 10.4 5.8 0.33 10.1 5.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CSRNP_N PF16019.5 CDJ65049.1 - 2.8 7.8 16.2 6.3 6.6 16.2 1.6 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CDC45 PF02724.14 CDJ65049.1 - 5.1 5.3 21.7 7.7 4.7 21.7 1.2 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.12 CDJ65049.1 - 5.8 7.1 15.9 8.1 6.6 15.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family MAT1 PF06391.13 CDJ65049.1 - 5.9 6.7 23.0 14 5.5 23.0 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 SUIM_assoc PF16619.5 CDJ65050.1 - 1.9 8.6 21.0 0.28 11.3 2.3 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Neur_chan_memb PF02932.16 CDJ65051.1 - 1.4 8.9 8.0 8 6.4 4.4 2.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 CDJ65051.1 - 2.3 7.0 35.1 0.07 12.0 4.3 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ65051.1 - 7.1 5.3 21.0 1.3 7.7 1.9 2.2 2 0 0 2 2 2 0 Presenilin Iso_dh PF00180.20 CDJ65052.1 - 1.9e-22 79.9 0.0 2.2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.20 CDJ65053.1 - 2.5e-42 145.3 0.0 2.8e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phosphorylase PF00343.20 CDJ65054.1 - 9.5e-300 996.0 0.0 1.1e-299 995.7 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase EGF_CA PF07645.15 CDJ65055.1 - 7.7e-214 691.8 539.0 1.6e-11 44.2 12.0 34.3 31 2 1 32 32 32 27 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ65055.1 - 5.8e-141 458.4 551.0 2.8e-10 40.2 16.3 33.5 33 1 1 34 34 34 29 EGF domain cEGF PF12662.7 CDJ65055.1 - 5e-135 438.8 313.8 3.4e-08 33.2 3.1 32.3 31 0 0 31 31 31 27 Complement Clr-like EGF-like EGF PF00008.27 CDJ65055.1 - 1.2e-68 226.9 429.8 4e-05 23.8 6.3 32.3 31 0 0 31 31 31 28 EGF-like domain hEGF PF12661.7 CDJ65055.1 - 6.6e-65 213.7 330.2 0.00016 22.2 2.4 32.6 30 0 0 30 30 30 27 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CDJ65055.1 - 9.6e-58 191.9 385.8 4e-07 30.0 7.5 32.7 32 0 0 32 32 32 26 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CDJ65055.1 - 1.8e-25 89.0 428.1 8.6e-05 22.8 8.3 31.9 31 2 2 33 33 33 24 Pvs28 EGF domain FXa_inhibition PF14670.6 CDJ65055.1 - 1.2e-21 76.7 499.0 0.00017 21.8 10.2 32.2 28 4 4 32 32 32 22 Coagulation Factor Xa inhibitory site DUF4366 PF14283.6 CDJ65055.1 - 0.078 13.0 1.1 0.58 10.2 1.1 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) HTH_20 PF12840.7 CDJ65055.1 - 0.26 11.4 2.2 51 4.0 0.0 4.6 5 0 0 5 5 5 0 Helix-turn-helix domain C2 PF00168.30 CDJ65057.1 - 1.3e-36 125.0 0.0 2.3e-13 50.3 0.0 4.8 5 0 0 5 5 5 4 C2 domain Ferlin_C PF16165.5 CDJ65057.1 - 0.02 14.9 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 Ferlin C-terminus SF3b1 PF08920.10 CDJ65058.1 - 2e-26 92.8 20.8 7.5e-24 84.5 5.5 3.7 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 HEAT PF02985.22 CDJ65058.1 - 4.8e-08 32.6 7.0 1.2 9.5 0.1 8.0 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 CDJ65058.1 - 1.5e-07 31.7 5.9 0.18 12.2 0.1 6.8 3 2 4 7 7 7 3 HEAT repeats UME PF08064.13 CDJ65058.1 - 7.9e-06 25.7 0.9 5.6 6.9 0.0 5.3 5 1 0 5 5 5 2 UME (NUC010) domain Adaptin_N PF01602.20 CDJ65058.1 - 6.1e-05 21.8 0.3 0.074 11.6 0.0 3.5 3 1 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 CDJ65058.1 - 8.7e-05 22.9 10.5 0.27 11.8 0.0 6.3 7 1 1 8 8 8 2 HEAT-like repeat NUC173 PF08161.12 CDJ65058.1 - 0.016 14.9 0.0 3.5 7.2 0.0 4.0 3 1 0 4 4 4 0 NUC173 domain Arm PF00514.23 CDJ65058.1 - 0.018 15.1 1.2 67 3.7 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 CDJ65058.1 - 0.02 14.5 0.1 1 8.9 0.0 2.7 2 0 0 2 2 2 0 CLASP N terminal Myb_DNA-binding PF00249.31 CDJ65059.1 - 1e-07 32.0 0.1 0.0013 18.9 0.0 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ65059.1 - 0.0051 17.0 0.1 0.15 12.3 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF5053 PF16476.5 CDJ65059.1 - 0.22 11.2 0.0 0.44 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) DUF3157 PF11355.8 CDJ65060.1 - 4.6 6.8 7.6 0.73 9.4 3.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3157) START PF01852.19 CDJ65062.1 - 9.2e-14 51.3 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 START domain KptA_kDCL PF18176.1 CDJ65062.1 - 0.027 14.3 0.1 0.03 14.2 0.1 1.4 1 1 0 1 1 1 0 KptA in kinetoplastid DICER domain SPX PF03105.19 CDJ65063.1 - 8.3e-05 22.7 20.5 0.00014 22.0 20.5 1.2 1 0 0 1 1 1 1 SPX domain NPR3 PF03666.13 CDJ65063.1 - 0.018 13.9 13.0 0.47 9.2 0.4 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 BUD22 PF09073.10 CDJ65063.1 - 0.063 12.6 21.3 0.09 12.1 21.3 1.1 1 0 0 1 1 1 0 BUD22 Spt20 PF12090.8 CDJ65063.1 - 0.094 12.3 37.0 0.045 13.3 32.5 2.0 2 0 0 2 2 2 0 Spt20 family SAPS PF04499.15 CDJ65063.1 - 0.21 10.3 6.7 0.33 9.7 6.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIP PF07454.11 CDJ65063.1 - 0.21 11.0 8.7 0.076 12.5 5.4 1.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) FAM76 PF16046.5 CDJ65063.1 - 0.76 9.1 14.2 0.63 9.3 8.2 2.1 2 0 0 2 2 2 0 FAM76 protein Connexin PF00029.19 CDJ65063.1 - 1.1 9.0 8.2 28 4.4 9.3 2.0 2 0 0 2 2 2 0 Connexin Thg1C PF14413.6 CDJ65063.1 - 1.2 9.3 8.3 2.9 8.1 8.3 1.5 1 0 0 1 1 1 0 Thg1 C terminal domain DUF4407 PF14362.6 CDJ65063.1 - 1.3 8.3 15.5 1.8 7.9 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Utp14 PF04615.13 CDJ65063.1 - 4 5.9 22.0 5.5 5.4 22.0 1.1 1 0 0 1 1 1 0 Utp14 protein DivIC PF04977.15 CDJ65063.1 - 9.3 6.1 15.1 19 5.1 15.1 1.5 1 0 0 1 1 1 0 Septum formation initiator eIF-3_zeta PF05091.12 CDJ65063.1 - 9.3 5.1 15.4 14 4.5 15.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AIF_C PF14721.6 CDJ65063.1 - 9.5 6.6 15.6 6.8 7.0 0.2 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TssO PF17561.2 CDJ65064.1 - 0.039 14.0 0.4 3 7.9 0.0 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssO GCSF PF16647.5 CDJ65064.1 - 1.2 9.0 11.7 0.059 13.2 5.4 2.0 2 0 0 2 2 2 0 Granulocyte colony-stimulating factor TLP-20 PF06088.11 CDJ65064.1 - 2.4 8.0 9.8 1.2 9.0 3.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Cwf_Cwc_15 PF04889.12 CDJ65064.1 - 6 6.5 19.7 0.41 10.3 3.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein HVSL PF09749.9 CDJ65065.1 - 1.5e-26 93.4 25.6 1.5e-26 93.4 25.6 3.3 1 1 0 2 2 2 1 Uncharacterised conserved protein Folliculin PF11704.8 CDJ65065.1 - 0.013 15.3 5.6 0.013 15.3 5.6 3.3 2 1 1 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport SAPS PF04499.15 CDJ65065.1 - 0.17 10.6 33.2 0.09 11.5 22.2 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PAT1 PF09770.9 CDJ65065.1 - 0.2 9.9 79.5 0.31 9.3 50.5 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SARAF PF06682.12 CDJ65065.1 - 2 8.0 46.6 1.7 8.2 10.2 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Tyrosinase PF00264.20 CDJ65065.1 - 4.5 7.5 28.2 2.5 8.3 2.6 2.3 2 0 0 2 2 2 0 Common central domain of tyrosinase PMI_typeI PF01238.21 CDJ65066.1 - 9.1e-32 110.7 37.0 1.7e-18 66.9 28.3 2.9 1 1 1 2 2 2 2 Phosphomannose isomerase type I DUF4366 PF14283.6 CDJ65066.1 - 3.5 7.6 21.5 2.7 8.0 0.6 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) UBA PF00627.31 CDJ65067.1 - 1.8e-06 27.7 0.2 3.6e-06 26.7 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 CDJ65067.1 - 0.0028 17.6 0.0 0.0033 17.5 0.0 1.1 1 0 0 1 1 1 1 HOIP UBA domain pair CUE PF02845.16 CDJ65067.1 - 0.0029 17.3 0.4 0.0068 16.1 0.0 1.7 2 0 0 2 2 2 1 CUE domain UBA_4 PF14555.6 CDJ65067.1 - 0.0099 15.7 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 1 UBA-like domain E3_UbLigase_EDD PF11547.8 CDJ65067.1 - 0.18 11.5 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD DUF1296 PF06972.11 CDJ65067.1 - 0.27 11.4 0.0 0.39 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) RRN3 PF05327.11 CDJ65068.1 - 0.001 17.8 0.6 0.0012 17.5 0.6 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 GrpE PF01025.19 CDJ65068.1 - 0.002 17.8 5.3 0.0026 17.4 5.3 1.1 1 0 0 1 1 1 1 GrpE UPF0147 PF03685.13 CDJ65068.1 - 0.0055 16.7 0.6 0.0086 16.1 0.6 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) PIN_8 PF18476.1 CDJ65068.1 - 0.015 15.2 1.9 0.018 14.9 1.9 1.3 1 0 0 1 1 1 0 PIN like domain Het-C PF07217.11 CDJ65068.1 - 0.023 13.2 1.2 0.027 13.0 1.2 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Efg1 PF10153.9 CDJ65068.1 - 0.023 15.0 3.7 0.034 14.5 3.7 1.3 1 0 0 1 1 1 0 rRNA-processing protein Efg1 DUF3490 PF11995.8 CDJ65068.1 - 0.034 14.0 1.8 0.039 13.8 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) DUF4407 PF14362.6 CDJ65068.1 - 0.052 12.9 1.9 0.052 12.9 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ECM11 PF15463.6 CDJ65068.1 - 0.056 14.0 3.6 0.16 12.5 3.6 1.8 1 1 0 1 1 1 0 Extracellular mutant protein 11 DUF883 PF05957.13 CDJ65068.1 - 0.058 14.0 1.2 1.1 9.9 0.7 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF5638 PF18688.1 CDJ65068.1 - 0.059 13.7 6.4 0.1 12.9 5.5 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5638) CCDC84 PF14968.6 CDJ65068.1 - 0.067 12.8 3.7 0.066 12.8 3.7 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 Mit_ribos_Mrp51 PF11709.8 CDJ65068.1 - 0.089 12.4 3.0 0.1 12.2 3.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit PdaC PF13739.6 CDJ65068.1 - 0.093 13.7 5.7 0.12 13.4 5.2 1.5 2 0 0 2 2 1 0 Deacetylase PdaC Z1 PF10593.9 CDJ65068.1 - 0.11 12.0 3.0 0.13 11.7 3.0 1.1 1 0 0 1 1 1 0 Z1 domain Kinetochor_Ybp2 PF08568.10 CDJ65068.1 - 0.17 10.3 2.9 0.22 10.0 2.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin HSCB_C PF07743.13 CDJ65068.1 - 0.72 10.4 7.1 2.3 8.7 7.1 2.1 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Uteroglobin PF01099.17 CDJ65068.1 - 5 7.5 6.0 3.8 7.9 4.8 1.5 2 0 0 2 2 1 0 Uteroglobin family DNTTIP1_dimer PF18192.1 CDJ65068.1 - 6 7.3 10.0 1.2 9.5 6.4 1.7 2 1 0 2 2 1 0 DNTTIP1 dimerisation domain LRRC37AB_C PF14914.6 CDJ65069.1 - 0.00048 20.1 10.7 0.0008 19.3 10.7 1.4 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain SpoIIP PF07454.11 CDJ65069.1 - 0.00089 18.8 8.1 0.00096 18.7 8.1 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) CSG2 PF16965.5 CDJ65069.1 - 0.0019 17.2 6.1 0.0022 17.0 6.1 1.2 1 0 0 1 1 1 1 Ceramide synthase regulator RR_TM4-6 PF06459.12 CDJ65069.1 - 0.0034 17.3 14.4 0.0034 17.3 14.4 1.4 2 0 0 2 2 1 1 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ65069.1 - 0.0048 16.0 12.5 0.0051 15.9 12.5 1.1 1 0 0 1 1 1 1 Solute carrier family 12 Lin-8 PF03353.15 CDJ65069.1 - 0.0057 16.3 14.8 0.0068 16.0 14.8 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist FAM60A PF15396.6 CDJ65069.1 - 0.0078 16.2 8.8 0.011 15.7 8.8 1.3 1 0 0 1 1 1 1 Protein Family FAM60A DUF3402 PF11882.8 CDJ65069.1 - 0.0086 15.2 13.3 0.012 14.8 13.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) DUF913 PF06025.12 CDJ65069.1 - 0.0099 14.9 4.6 0.013 14.6 4.6 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Patched PF02460.18 CDJ65069.1 - 0.016 13.3 0.2 0.019 13.1 0.2 1.1 1 0 0 1 1 1 0 Patched family Connexin PF00029.19 CDJ65069.1 - 0.019 14.7 10.2 0.03 14.1 10.2 1.3 1 0 0 1 1 1 0 Connexin Anoctamin PF04547.12 CDJ65069.1 - 0.024 13.5 2.4 0.029 13.2 2.4 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel PAT1 PF09770.9 CDJ65069.1 - 0.031 12.6 30.6 0.036 12.4 30.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.16 CDJ65069.1 - 0.033 13.1 8.0 0.041 12.8 8.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein K_channel_TID PF07941.11 CDJ65069.1 - 0.036 14.5 11.7 0.036 14.5 11.7 5.2 3 1 0 3 3 2 0 Potassium channel Kv1.4 tandem inactivation domain eIF-3_zeta PF05091.12 CDJ65069.1 - 0.038 13.0 23.2 0.061 12.3 23.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Nucleoside_tran PF01733.18 CDJ65069.1 - 0.049 13.0 4.4 0.071 12.5 4.4 1.2 1 0 0 1 1 1 0 Nucleoside transporter PXA PF02194.15 CDJ65069.1 - 0.054 13.5 13.6 0.072 13.1 13.6 1.3 1 0 0 1 1 1 0 PXA domain Peptidase_S64 PF08192.11 CDJ65069.1 - 0.061 11.8 12.2 0.076 11.5 12.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Otopetrin PF03189.13 CDJ65069.1 - 0.065 12.1 5.5 0.071 11.9 5.5 1.3 1 0 0 1 1 1 0 Otopetrin MDM10 PF12519.8 CDJ65069.1 - 0.084 11.7 8.7 0.097 11.5 8.7 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PBP1_TM PF14812.6 CDJ65069.1 - 0.12 12.8 6.6 0.19 12.1 6.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HCO3_cotransp PF00955.21 CDJ65069.1 - 0.12 11.2 5.2 0.14 10.9 5.2 1.1 1 0 0 1 1 1 0 HCO3- transporter family ALMT PF11744.8 CDJ65069.1 - 0.13 11.0 12.8 0.15 10.9 12.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 CDJ65069.1 - 0.15 10.1 13.7 0.15 10.1 13.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.11 CDJ65069.1 - 0.16 11.4 3.8 0.17 11.3 3.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2828 PF11443.8 CDJ65069.1 - 0.17 9.9 18.2 0.22 9.5 18.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.16 CDJ65069.1 - 0.18 11.8 15.5 0.29 11.2 15.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Draxin PF15550.6 CDJ65069.1 - 0.27 11.1 14.0 0.35 10.7 14.0 1.2 1 0 0 1 1 1 0 Draxin DUF3112 PF11309.8 CDJ65069.1 - 0.3 10.5 4.2 0.38 10.2 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) CAF1 PF04857.20 CDJ65069.1 - 0.38 9.9 7.4 0.41 9.8 7.4 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease CD20 PF04103.15 CDJ65069.1 - 0.44 10.6 16.0 0.85 9.7 3.7 3.1 1 1 2 3 3 3 0 CD20-like family RIFIN PF02009.16 CDJ65069.1 - 0.5 10.2 20.7 0.55 10.1 14.1 2.1 2 0 0 2 2 2 0 Rifin Folate_carrier PF01770.18 CDJ65069.1 - 0.56 8.9 8.6 0.67 8.6 8.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier Gti1_Pac2 PF09729.9 CDJ65069.1 - 0.74 9.9 12.8 1.3 9.0 12.8 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Sec62 PF03839.16 CDJ65069.1 - 0.79 9.2 11.3 1.2 8.6 11.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S15 PF02129.18 CDJ65069.1 - 0.8 9.2 23.8 0.088 12.4 18.4 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Scs3p PF10261.9 CDJ65069.1 - 0.82 9.1 10.8 0.58 9.6 9.3 1.5 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM MDM31_MDM32 PF08118.11 CDJ65069.1 - 0.97 8.0 11.1 1.6 7.3 11.1 1.4 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Shadoo PF14999.6 CDJ65069.1 - 1.2 9.2 24.7 0.24 11.5 6.7 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective SART-1 PF03343.13 CDJ65069.1 - 1.5 7.2 27.8 2.1 6.8 27.8 1.1 1 0 0 1 1 1 0 SART-1 family Paramyxo_ncap PF00973.19 CDJ65069.1 - 2 7.3 12.0 2.8 6.8 12.0 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein O-antigen_lig PF13425.6 CDJ65069.1 - 2.1 7.0 6.1 2.6 6.8 6.1 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein LptF_LptG PF03739.14 CDJ65069.1 - 2.2 7.0 5.9 2.8 6.7 5.9 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Topoisom_I_N PF02919.15 CDJ65069.1 - 2.5 7.5 11.2 3.6 7.0 11.2 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Orf78 PF06024.12 CDJ65069.1 - 2.9 8.2 14.4 27 5.1 14.4 2.5 1 1 0 1 1 1 0 Orf78 (ac78) Baculo_PP31 PF05311.11 CDJ65069.1 - 3.7 6.9 15.8 5.4 6.4 15.8 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Ribosomal_60s PF00428.19 CDJ65069.1 - 3.9 8.1 36.5 4 8.1 15.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cellulose_synt PF03552.14 CDJ65069.1 - 4.2 5.7 4.3 4.6 5.6 4.3 1.1 1 0 0 1 1 1 0 Cellulose synthase Membralin PF09746.9 CDJ65069.1 - 4.5 6.2 11.8 6.1 5.8 11.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein RskA PF10099.9 CDJ65069.1 - 4.6 7.5 50.3 8.8 6.6 27.4 2.8 1 1 1 2 2 1 0 Anti-sigma-K factor rskA MMU163 PF17119.5 CDJ65069.1 - 4.6 6.3 9.4 7.6 5.6 9.4 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Peptidase_U57 PF05582.12 CDJ65069.1 - 4.6 6.4 12.6 8 5.6 12.6 1.5 1 0 0 1 1 1 0 YabG peptidase U57 DUF2052 PF09747.9 CDJ65069.1 - 5 7.2 24.7 1.4 9.0 21.9 1.4 2 0 0 2 2 1 0 Coiled-coil domain containing protein (DUF2052) DUF2347 PF09804.9 CDJ65069.1 - 5.2 6.6 10.5 7.2 6.1 10.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4746 PF15928.5 CDJ65069.1 - 7.1 6.0 12.6 9.6 5.5 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Endonuc_Holl PF10107.9 CDJ65069.1 - 9.2 6.1 16.5 4.3 7.2 14.1 1.8 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF2076 PF09849.9 CDJ65070.1 - 0.0012 19.0 4.2 0.0013 18.9 4.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF620 PF04788.12 CDJ65070.1 - 0.0091 15.4 0.1 0.01 15.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF620) CDRT4 PF15213.6 CDJ65070.1 - 0.011 16.4 0.3 0.013 16.2 0.3 1.1 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Spt20 PF12090.8 CDJ65070.1 - 0.02 14.5 7.5 0.021 14.4 7.5 1.1 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ65070.1 - 0.051 12.8 6.3 0.053 12.7 6.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Androgen_recep PF02166.16 CDJ65070.1 - 0.078 11.8 8.5 0.079 11.8 8.5 1.1 1 0 0 1 1 1 0 Androgen receptor DUF2722 PF10846.8 CDJ65070.1 - 0.087 11.8 5.5 0.088 11.7 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ65070.1 - 0.46 10.6 13.2 0.74 9.9 13.2 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2967 PF11179.8 CDJ65070.1 - 2.6 6.0 6.0 2.7 6.0 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Peptidase_M3 PF01432.20 CDJ65072.1 - 2.1e-11 43.8 0.0 4.3e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M3 COE1_HLH PF16423.5 CDJ65072.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain MFS_2 PF13347.6 CDJ65073.1 - 0.0019 16.8 1.3 0.0025 16.4 1.3 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein CDC50 PF03381.15 CDJ65074.1 - 1.1e-19 71.1 0.0 1.3e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Herpes_LMP1 PF05297.11 CDJ65074.1 - 0.055 12.7 1.1 0.11 11.7 1.1 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2722 PF10846.8 CDJ65075.1 - 0.02 13.8 7.9 0.023 13.6 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FA_desaturase PF00487.24 CDJ65075.1 - 0.021 14.7 2.0 0.023 14.6 2.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Glyco_trans_2_3 PF13632.6 CDJ65075.1 - 0.023 14.6 3.6 0.024 14.6 3.6 1.1 1 0 0 1 1 1 0 Glycosyl transferase family group 2 TniB PF05621.11 CDJ65075.1 - 0.049 13.0 1.4 0.065 12.6 1.4 1.1 1 0 0 1 1 1 0 Bacterial TniB protein Maf1 PF09174.10 CDJ65075.1 - 0.079 13.1 2.4 0.099 12.8 2.4 1.1 1 0 0 1 1 1 0 Maf1 regulator Spt20 PF12090.8 CDJ65075.1 - 0.76 9.3 14.9 0.85 9.2 14.9 1.1 1 0 0 1 1 1 0 Spt20 family Phage_holin_3_6 PF07332.11 CDJ65075.1 - 0.8 9.8 21.8 1.1 9.3 21.8 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III CobD_Cbib PF03186.13 CDJ65075.1 - 0.85 8.8 3.9 1.1 8.4 3.9 1.2 1 0 0 1 1 1 0 CobD/Cbib protein YqzE PF14038.6 CDJ65075.1 - 3.5 7.7 5.3 5.8 7.0 5.3 1.3 1 0 0 1 1 1 0 YqzE-like protein SMP PF04927.12 CDJ65077.1 - 9.2 6.8 6.9 0.69 10.4 0.6 2.1 2 0 0 2 2 2 0 Seed maturation protein RNA_pol_Rpb1_2 PF00623.20 CDJ65079.1 - 7.9e-48 162.8 0.2 6.4e-31 107.8 0.0 2.9 3 1 0 3 3 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 CDJ65079.1 - 6e-17 61.9 0.9 4.6e-14 52.5 0.0 3.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 CDJ65079.1 - 5.8e-14 52.3 0.0 1.3e-13 51.2 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 3 SUIM_assoc PF16619.5 CDJ65079.1 - 0.0067 16.5 36.8 0.47 10.6 11.2 3.9 3 0 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ65079.1 - 0.035 14.4 41.3 0.27 11.5 0.2 5.0 4 1 1 5 5 5 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ65079.1 - 0.11 12.4 32.5 0.19 11.7 4.7 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Dehydrin PF00257.19 CDJ65079.1 - 0.25 11.9 0.0 0.25 11.9 0.0 4.1 4 0 0 4 4 4 0 Dehydrin INTS5_N PF14837.6 CDJ65079.1 - 0.42 10.2 3.5 0.26 10.9 0.2 2.3 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus Spt20 PF12090.8 CDJ65079.1 - 1 8.9 38.6 1.3 8.6 6.5 3.2 3 0 0 3 3 3 0 Spt20 family DUF3446 PF11928.8 CDJ65079.1 - 1.1 9.6 14.8 0.13 12.5 3.8 3.5 3 0 0 3 3 3 0 Early growth response N-terminal domain DUF2052 PF09747.9 CDJ65079.1 - 2.5 8.2 13.9 3.4 7.8 0.4 3.2 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) EPL1 PF10513.9 CDJ65079.1 - 2.6 8.4 13.3 8 6.8 0.8 3.3 3 0 0 3 3 3 0 Enhancer of polycomb-like ANAPC_CDC26 PF10471.9 CDJ65079.1 - 7 7.6 36.4 1 10.3 9.0 4.0 4 0 0 4 4 3 0 Anaphase-promoting complex APC subunit CDC26 SUIM_assoc PF16619.5 CDJ65080.1 - 0.00017 21.6 32.9 0.0002 21.4 3.4 4.1 3 1 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 CDJ65080.1 - 0.015 16.2 0.7 0.015 16.2 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Peptidase_S49_N PF08496.10 CDJ65080.1 - 1.8 8.6 10.3 0.37 10.8 0.5 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF2628 PF10947.8 CDJ65080.1 - 6.6 7.2 7.2 3.2 8.2 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) Pex26 PF07163.12 CDJ65080.1 - 7.6 5.7 23.1 4.7 6.4 5.8 2.3 2 0 0 2 2 2 0 Pex26 protein HA2 PF04408.23 CDJ65080.1 - 9.4 6.6 6.9 8 6.8 0.6 2.5 2 0 0 2 2 2 0 Helicase associated domain (HA2) DUF1917 PF08939.10 CDJ65081.1 - 0.0075 16.2 2.7 0.0091 15.9 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) DUF3648 PF12364.8 CDJ65081.1 - 0.14 12.4 4.5 0.17 12.1 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) DUF775 PF05603.12 CDJ65081.1 - 0.47 9.9 6.3 0.49 9.9 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) TMEM65 PF10507.9 CDJ65081.1 - 1.9 8.5 3.5 1.3 9.0 2.1 1.4 1 1 0 1 1 1 0 Transmembrane protein 65 PIN_8 PF18476.1 CDJ65081.1 - 2.7 7.8 7.6 3 7.6 7.6 1.0 1 0 0 1 1 1 0 PIN like domain M16C_assoc PF08367.11 CDJ65082.1 - 1e-18 67.4 4.3 1.7e-16 60.1 4.3 2.6 1 1 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CDJ65082.1 - 6e-09 36.2 1.2 2.3e-07 31.0 0.0 3.1 3 1 0 3 3 3 1 Peptidase M16 inactive domain DUF4240 PF14024.6 CDJ65082.1 - 0.049 13.8 0.3 0.14 12.4 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) CAF1 PF04857.20 CDJ65083.1 - 0.00017 20.9 0.0 0.00017 20.9 0.0 2.2 1 1 1 2 2 2 1 CAF1 family ribonuclease DUF4175 PF13779.6 CDJ65083.1 - 0.2 9.5 12.2 0.22 9.4 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.10 CDJ65083.1 - 0.27 9.9 18.1 0.35 9.5 18.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ65083.1 - 0.48 10.0 23.8 0.73 9.4 23.8 1.3 1 0 0 1 1 1 0 Spt20 family DUF5336 PF17270.2 CDJ65083.1 - 3.6 7.2 8.0 5.8 6.5 8.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5336) SR-25 PF10500.9 CDJ65083.1 - 7.8 6.0 13.2 2 8.0 5.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4407 PF14362.6 CDJ65083.1 - 8.6 5.6 8.3 9.7 5.4 4.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pox_Ag35 PF03286.14 CDJ65084.1 - 0.072 12.9 18.2 0.085 12.6 18.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Exonuc_VII_L PF02601.15 CDJ65084.1 - 0.46 10.0 40.5 0.53 9.8 40.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Presenilin PF01080.17 CDJ65084.1 - 0.92 8.2 41.8 1.1 8.0 41.8 1.0 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ65084.1 - 1.8 7.5 33.6 2 7.3 33.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4746 PF15928.5 CDJ65084.1 - 2 7.8 22.8 2.6 7.4 22.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) V_ATPase_I PF01496.19 CDJ65084.1 - 2.2 6.1 29.5 2.7 5.8 29.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 CDJ65084.1 - 2.2 6.5 29.1 2.3 6.4 29.1 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.6 CDJ65084.1 - 2.2 8.2 27.7 2.8 7.9 27.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ65084.1 - 2.7 7.8 36.9 2.9 7.6 36.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ65084.1 - 4 6.2 25.3 4.2 6.1 25.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Rtf2 PF04641.12 CDJ65084.1 - 4.4 6.6 30.1 5.3 6.3 30.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger NPR3 PF03666.13 CDJ65084.1 - 4.5 6.0 33.5 5.5 5.7 33.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MCM_bind PF09739.9 CDJ65084.1 - 4.6 5.6 28.9 5.2 5.4 28.9 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NARP1 PF12569.8 CDJ65084.1 - 4.7 6.0 28.8 6.8 5.5 28.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3295 PF11702.8 CDJ65084.1 - 6.7 6.0 32.9 8.3 5.6 32.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CCSAP PF15748.5 CDJ65084.1 - 8.1 6.5 42.2 8.9 6.4 42.2 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF572 PF04502.13 CDJ65084.1 - 8.2 5.9 32.5 8.9 5.8 32.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) PNISR PF15996.5 CDJ65084.1 - 9 6.5 38.7 11 6.2 38.7 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SUIM_assoc PF16619.5 CDJ65085.1 - 4.6e-10 39.4 5.9 0.0021 18.1 5.9 2.9 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Activator_LAG-3 PF11498.8 CDJ65085.1 - 1.5e-05 24.2 27.3 2.3e-05 23.6 27.3 1.3 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Presenilin PF01080.17 CDJ65085.1 - 0.0017 17.2 4.7 0.0021 16.9 4.7 1.3 1 0 0 1 1 1 1 Presenilin CAF1 PF04857.20 CDJ65085.1 - 0.0019 17.4 0.3 0.0019 17.4 0.3 2.3 2 1 0 2 2 1 1 CAF1 family ribonuclease Ribosomal_60s PF00428.19 CDJ65085.1 - 0.0085 16.7 15.2 0.015 15.9 13.2 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein RskA PF10099.9 CDJ65085.1 - 0.0089 16.3 14.3 0.2 11.9 8.1 2.2 2 0 0 2 2 2 2 Anti-sigma-K factor rskA eIF-3_zeta PF05091.12 CDJ65085.1 - 0.009 15.0 10.7 0.009 15.0 10.7 1.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIP5K PF01504.18 CDJ65085.1 - 0.014 14.7 2.2 0.014 14.7 2.2 1.5 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Dicty_REP PF05086.12 CDJ65085.1 - 0.022 12.8 2.1 0.033 12.2 2.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SpoIIP PF07454.11 CDJ65085.1 - 0.14 11.6 10.3 0.017 14.6 5.7 1.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 CDJ65085.1 - 0.18 11.5 2.8 0.15 11.8 1.1 1.7 2 0 0 2 2 2 0 Connexin LAP1C PF05609.12 CDJ65085.1 - 0.4 9.7 15.8 0.58 9.2 15.8 1.2 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CLN3 PF02487.17 CDJ65085.1 - 0.46 9.5 2.8 0.77 8.7 2.8 1.4 1 0 0 1 1 1 0 CLN3 protein CCDC53 PF10152.9 CDJ65085.1 - 0.54 10.7 14.8 7.3 7.0 11.3 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex EIIBC-GUT_N PF03612.14 CDJ65085.1 - 1.8 8.3 9.3 2.2 8.0 5.9 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus TFIIA PF03153.13 CDJ65085.1 - 2.9 7.8 35.1 4.1 7.3 35.1 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3824 PF12868.7 CDJ65085.1 - 7.1 7.3 19.5 0.61 10.7 4.4 2.4 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Usp PF00582.26 CDJ65085.1 - 10 6.7 6.9 4.6 7.8 1.5 2.2 2 0 0 2 2 2 0 Universal stress protein family NIF PF03031.18 CDJ65086.1 - 1.3e-24 86.8 0.0 7e-12 45.4 0.0 2.7 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase DUF2722 PF10846.8 CDJ65086.1 - 0.00078 18.5 0.2 0.00078 18.5 0.2 13.0 8 3 2 11 11 11 3 Protein of unknown function (DUF2722) DUF4667 PF15700.5 CDJ65086.1 - 0.014 15.5 0.0 0.014 15.5 0.0 11.2 5 3 4 9 9 9 0 Domain of unknown function (DUF4667) INCENP_ARK-bind PF03941.15 CDJ65087.1 - 0.00015 21.6 0.2 0.00015 21.6 0.2 2.9 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region O-antigen_lig PF13425.6 CDJ65087.1 - 0.00031 19.7 0.0 0.00064 18.6 0.0 1.4 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Mito_carr PF00153.27 CDJ65088.1 - 1.1e-52 175.9 3.8 1.9e-20 72.6 0.0 5.2 5 0 0 5 5 5 4 Mitochondrial carrier protein Serine_protease PF18405.1 CDJ65088.1 - 0.039 13.1 0.3 0.16 11.1 0.1 1.9 2 0 0 2 2 2 0 Gammaproteobacterial serine protease SUIM_assoc PF16619.5 CDJ65088.1 - 0.61 10.2 3.2 1.5 8.9 1.8 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Mre11_DNA_bind PF04152.14 CDJ65089.1 - 2.2e-27 96.5 0.0 7.7e-25 88.2 0.0 3.5 2 1 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CDJ65089.1 - 5.6e-14 53.1 1.5 1.9e-08 35.0 0.0 2.6 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ65089.1 - 5.2e-09 36.5 0.0 0.00049 20.3 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain TniQ PF06527.11 CDJ65089.1 - 0.091 13.5 0.3 3.3 8.4 0.1 2.5 2 0 0 2 2 2 0 TniQ SlyX PF04102.12 CDJ65090.1 - 9.5e-05 22.9 7.7 1.1 9.9 1.4 3.7 3 0 0 3 3 3 2 SlyX Yuri_gagarin PF15934.5 CDJ65090.1 - 0.03 14.2 0.2 0.03 14.2 0.2 3.0 3 0 0 3 3 3 0 Yuri gagarin FlaC_arch PF05377.11 CDJ65090.1 - 0.069 13.5 5.0 0.49 10.8 0.1 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 CDJ65090.1 - 1.1 9.7 13.9 1.4 9.3 1.1 3.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MscS_porin PF12795.7 CDJ65090.1 - 1.3 8.5 24.8 0.21 11.1 9.6 3.3 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Syntaxin-6_N PF09177.11 CDJ65090.1 - 1.7 9.3 12.1 3.1 8.4 0.4 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 CDJ65090.1 - 2.9 8.1 11.0 4.1 7.6 0.1 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family RNA_pol_Rpb4 PF03874.16 CDJ65092.1 - 5e-06 26.8 0.2 2.4e-05 24.7 0.0 2.3 2 1 0 2 2 2 1 RNA polymerase Rpb4 DER1 PF04511.15 CDJ65093.1 - 3.3e-44 151.1 15.0 3.8e-44 150.9 15.0 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 CDJ65093.1 - 5.6e-06 26.4 15.8 9.8e-06 25.6 15.8 1.3 1 0 0 1 1 1 1 Rhomboid family DUF373 PF04123.13 CDJ65093.1 - 0.8 9.1 5.0 0.95 8.8 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) zf-B_box PF00643.24 CDJ65094.1 - 1.5e-12 47.5 14.9 2.2e-06 27.7 6.6 2.3 2 0 0 2 2 2 2 B-box zinc finger PARP PF00644.20 CDJ65094.1 - 0.0053 16.4 0.3 0.024 14.2 0.1 2.2 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Pec_lyase_N PF04431.13 CDJ65094.1 - 0.15 12.3 0.3 0.62 10.3 0.0 2.1 2 0 0 2 2 2 0 Pectate lyase, N terminus Cript PF10235.9 CDJ65094.1 - 5.4 7.7 6.5 3.1 8.4 3.8 2.0 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Leu_Phe_trans PF03588.14 CDJ65095.1 - 1.1e-14 54.3 0.0 1.2e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 Leucyl/phenylalanyl-tRNA protein transferase Phage_holin_2_1 PF04971.12 CDJ65099.1 - 0.086 12.9 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage P21 holin S Utp11 PF03998.13 CDJ65100.1 - 2.3e-15 57.2 47.5 1.4e-14 54.6 47.5 2.2 1 1 0 1 1 1 1 Utp11 protein RskA PF10099.9 CDJ65100.1 - 0.00039 20.8 10.1 0.00039 20.8 10.1 3.1 1 1 2 3 3 3 1 Anti-sigma-K factor rskA DUF2935 PF11155.8 CDJ65100.1 - 0.0015 18.9 0.0 0.13 12.6 0.0 2.4 1 1 0 2 2 2 1 Domain of unknown function (DUF2935) SEEEED PF14797.6 CDJ65100.1 - 3.1 8.0 32.1 0.95 9.6 14.5 2.6 1 1 1 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Exonuc_VII_L PF02601.15 CDJ65102.1 - 1.1e-05 25.2 9.3 1.1e-05 25.2 9.3 3.5 4 0 0 4 4 4 1 Exonuclease VII, large subunit DUF4667 PF15700.5 CDJ65102.1 - 0.00014 22.0 1.6 0.00014 22.0 1.6 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) Het-C PF07217.11 CDJ65102.1 - 3.3 6.1 17.8 5.6 5.4 17.8 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C FapA PF03961.13 CDJ65102.1 - 9.7 4.7 14.7 15 4.0 14.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Kinesin PF00225.23 CDJ65103.1 - 2.8e-92 309.2 1.6 2.8e-92 309.2 1.6 5.9 5 2 0 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ65103.1 - 7.7e-12 45.4 0.4 7.7e-12 45.4 0.4 4.6 5 0 0 5 5 5 2 Microtubule binding DUF2722 PF10846.8 CDJ65103.1 - 0.00015 20.9 10.2 0.00015 20.9 10.2 16.3 11 5 4 15 15 15 4 Protein of unknown function (DUF2722) DUF755 PF05501.11 CDJ65103.1 - 0.00078 19.7 3.3 0.00078 19.7 3.3 24.3 23 2 3 26 26 26 2 Domain of unknown function (DUF755) YL1 PF05764.13 CDJ65103.1 - 0.0047 17.1 2.3 0.0047 17.1 2.3 10.1 8 3 1 9 9 9 1 YL1 nuclear protein SLC12 PF03522.15 CDJ65105.1 - 1.5 7.8 26.3 2.4 7.1 26.3 1.4 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ65105.1 - 3.4 6.0 7.7 5.2 5.4 7.7 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LMBR1 PF04791.16 CDJ65105.1 - 8.4 5.2 6.6 10 4.9 6.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Proteasome PF00227.26 CDJ65106.1 - 1.6e-29 102.7 0.0 2.5e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ65106.1 - 1.2e-11 44.1 0.1 2.8e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_M20 PF01546.28 CDJ65106.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.3 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 RskA PF10099.9 CDJ65106.1 - 2.6 8.3 7.5 5.4 7.3 7.5 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TMEM18 PF14770.6 CDJ65107.1 - 0.75 9.8 3.5 1.2 9.1 0.0 2.8 3 0 0 3 3 3 0 Transmembrane protein 18 Gln-synt_C PF00120.24 CDJ65108.1 - 1.9e-83 280.3 1.9 6.1e-52 176.7 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain SR-25 PF10500.9 CDJ65109.1 - 0.0024 17.5 20.4 0.0024 17.5 20.4 7.7 7 1 1 8 8 8 3 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ65109.1 - 0.0087 16.3 24.8 0.0087 16.3 24.8 9.8 8 2 1 9 9 9 1 Domain of unknown function (DUF755) UFD1 PF03152.14 CDJ65110.1 - 1.2e-68 230.0 0.0 7.6e-68 227.4 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 DUF2722 PF10846.8 CDJ65110.1 - 0.0052 15.8 19.7 0.0052 15.8 19.7 4.2 4 1 0 4 4 3 1 Protein of unknown function (DUF2722) AAA_23 PF13476.6 CDJ65110.1 - 0.015 15.8 6.2 0.015 15.8 6.2 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 CDJ65110.1 - 0.016 16.1 1.0 0.063 14.2 1.0 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat CLN3 PF02487.17 CDJ65110.1 - 0.032 13.3 2.4 0.081 12.0 2.4 1.6 1 0 0 1 1 1 0 CLN3 protein DUF4471 PF14740.6 CDJ65110.1 - 0.067 12.4 3.4 0.11 11.7 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) SID-1_RNA_chan PF13965.6 CDJ65110.1 - 0.16 10.3 0.2 0.27 9.6 0.2 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Connexin PF00029.19 CDJ65110.1 - 0.29 10.8 5.3 0.63 9.8 5.3 1.5 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 CDJ65110.1 - 0.32 9.9 3.8 0.85 8.5 3.8 1.7 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4638 PF15472.6 CDJ65110.1 - 0.45 10.2 5.6 0.91 9.2 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) V_ATPase_I PF01496.19 CDJ65110.1 - 0.52 8.2 9.5 0.88 7.4 9.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mitofilin PF09731.9 CDJ65110.1 - 0.52 9.1 44.2 0.17 10.7 9.5 2.4 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Tim54 PF11711.8 CDJ65110.1 - 1.2 7.8 9.8 2.8 6.6 9.8 1.6 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ALMT PF11744.8 CDJ65110.1 - 2.1 7.1 5.7 4.7 5.9 5.7 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter Scs3p PF10261.9 CDJ65110.1 - 2.3 7.6 4.6 25 4.3 2.2 2.4 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM eIF-3_zeta PF05091.12 CDJ65110.1 - 2.6 6.9 17.3 0.32 9.9 12.2 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4770 PF15994.5 CDJ65110.1 - 2.7 8.2 16.1 0.96 9.7 11.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Tau95_N PF17682.1 CDJ65110.1 - 5.8 7.1 8.9 8.5 6.6 5.8 2.5 2 0 0 2 2 2 0 Tau95 Triple barrel domain EIIBC-GUT_N PF03612.14 CDJ65110.1 - 7.3 6.3 12.9 0.97 9.2 8.0 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Methyltransf_34 PF11312.8 CDJ65110.1 - 9.2 5.4 23.0 0.006 15.9 9.6 2.6 2 0 0 2 2 1 0 Putative SAM-dependent methyltransferase Apt1 PF10351.9 CDJ65110.1 - 9.5 4.9 28.8 1.6 7.5 8.6 3.0 3 0 0 3 3 3 0 Golgi-body localisation protein domain Paf1 PF03985.13 CDJ65110.1 - 9.5 5.1 19.1 26 3.6 19.1 1.7 1 0 0 1 1 1 0 Paf1 AF-4 PF05110.13 CDJ65111.1 - 0.013 13.7 40.2 0.016 13.3 40.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3273 PF11677.8 CDJ65112.1 - 3.1e-09 36.5 0.4 4.6e-09 36.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) RRM_1 PF00076.22 CDJ65114.1 - 1.4e-31 108.2 0.2 2.2e-14 53.0 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ65114.1 - 2.7e-05 24.2 0.0 0.037 14.1 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 CDJ65114.1 - 0.053 13.2 0.2 0.69 9.6 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain TPR_2 PF07719.17 CDJ65115.1 - 2e-09 36.9 12.1 8.8e-05 22.3 0.7 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ65115.1 - 6.5e-07 28.9 5.0 0.006 16.4 0.2 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ65115.1 - 1e-05 25.1 3.9 1.7 8.4 0.0 4.1 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 CDJ65115.1 - 1.3e-05 25.0 4.6 0.15 12.4 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ65115.1 - 0.00035 21.1 5.1 0.00035 21.1 5.1 8.6 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ65115.1 - 0.0038 17.8 0.9 0.0038 17.8 0.9 6.5 8 0 0 8 8 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ65115.1 - 0.042 13.9 0.4 0.042 13.9 0.4 3.4 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MMS22L_C PF14911.6 CDJ65115.1 - 0.075 12.1 5.7 0.043 12.9 0.5 2.8 3 0 0 3 3 3 0 S-phase genomic integrity recombination mediator, C-terminal TPR_9 PF13371.6 CDJ65115.1 - 0.65 10.2 10.8 0.11 12.7 4.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ65115.1 - 0.99 9.9 8.4 1 9.9 0.3 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Nop PF01798.18 CDJ65116.1 - 2.1e-80 269.5 0.2 3.6e-80 268.7 0.2 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CDJ65116.1 - 4.2e-16 59.1 1.0 1e-15 57.9 1.0 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF3138 PF11336.8 CDJ65116.1 - 0.13 10.9 1.6 0.22 10.1 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ATP-cone PF03477.16 CDJ65116.1 - 0.13 12.9 1.4 9.3 6.9 0.4 3.0 2 1 1 3 3 3 0 ATP cone domain PIP5K PF01504.18 CDJ65117.1 - 1.3e-24 86.9 0.0 1e-16 61.0 0.0 3.0 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 CDJ65117.1 - 3e-14 52.9 10.9 3e-14 52.9 10.9 2.7 2 0 0 2 2 2 1 FYVE zinc finger Cpn60_TCP1 PF00118.24 CDJ65117.1 - 0.0015 17.3 0.0 0.0061 15.2 0.0 1.9 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family Imm30 PF15565.6 CDJ65117.1 - 0.22 11.6 0.0 0.42 10.7 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 30 NFACT-R_1 PF05670.13 CDJ65118.1 - 7.7e-10 39.4 0.0 8e-09 36.1 0.0 2.3 1 1 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 CDJ65118.1 - 0.012 15.8 0.0 1.4 9.1 0.0 2.8 1 1 0 2 2 2 0 NFACT protein RNA binding domain TFIIA PF03153.13 CDJ65118.1 - 1.3 9.0 12.1 1.8 8.4 12.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_topoisoIV PF00521.20 CDJ65119.1 - 6.9e-84 282.2 0.1 1.2e-77 261.7 0.0 2.3 2 0 0 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 CDJ65119.1 - 1.4e-29 101.3 10.2 1.7e-09 37.0 0.0 5.8 6 0 0 6 6 6 4 DNA gyrase C-terminal domain, beta-propeller FliT PF05400.13 CDJ65119.1 - 0.32 11.9 16.5 0.035 14.9 10.5 2.5 1 1 1 2 2 2 0 Flagellar protein FliT MAT1 PF06391.13 CDJ65119.1 - 2.1 8.1 12.8 0.3 10.9 8.5 1.7 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 PNTB PF02233.16 CDJ65120.1 - 6.2e-29 101.2 0.0 1.1e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 CDJ65120.1 - 2.1e-21 76.3 0.0 8.8e-21 74.2 0.0 2.0 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CDJ65120.1 - 0.0037 17.6 0.0 0.06 13.6 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain FAD_oxidored PF12831.7 CDJ65120.1 - 0.99 8.7 7.6 0.046 13.1 1.2 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Presenilin PF01080.17 CDJ65120.1 - 1 8.1 4.2 1.4 7.6 4.2 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ65120.1 - 3.2 7.7 17.0 4.6 7.1 17.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CASP_C PF08172.12 CDJ65121.1 - 2e-13 50.3 6.8 2.5e-09 36.9 0.1 6.2 2 1 3 5 5 5 2 CASP C terminal PHD PF00628.29 CDJ65122.1 - 4.8e-14 52.0 40.7 2.9e-10 39.9 17.6 4.4 2 1 2 4 4 4 2 PHD-finger PHD_2 PF13831.6 CDJ65122.1 - 6.2e-06 25.7 11.1 0.00021 20.8 0.6 5.1 6 0 0 6 6 6 2 PHD-finger C1_1 PF00130.22 CDJ65122.1 - 0.00073 19.4 14.3 0.0055 16.6 4.8 4.7 3 2 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Auto_anti-p27 PF06677.12 CDJ65122.1 - 0.11 12.6 1.1 0.11 12.6 1.1 4.9 5 0 0 5 5 5 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RING_2 PF13639.6 CDJ65122.1 - 0.15 12.4 34.1 4.1 7.8 16.2 4.3 2 2 2 4 4 4 0 Ring finger domain zf-PHD-like PF15446.6 CDJ65122.1 - 1.5 8.4 23.2 0.55 9.8 1.9 3.2 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.16 CDJ65122.1 - 6.8 6.9 36.4 0.17 12.1 6.0 3.7 1 1 3 4 4 4 0 FYVE-type zinc finger Rhodanese_C PF12368.8 CDJ65123.1 - 0.36 11.2 5.9 2.5 8.6 0.3 2.6 2 0 0 2 2 2 0 Rhodanase C-terminal PHD PF00628.29 CDJ65123.1 - 0.56 10.2 12.0 0.37 10.7 1.4 2.5 2 0 0 2 2 2 0 PHD-finger DUF1181 PF06680.11 CDJ65125.1 - 0.1 12.4 0.2 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1181) Dabb PF07876.12 CDJ65126.1 - 1.2e-18 67.5 0.3 1.4e-18 67.3 0.3 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Lactamase_B_2 PF12706.7 CDJ65127.1 - 4.9e-25 88.2 0.1 6.5e-16 58.4 0.0 2.6 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDJ65127.1 - 4.5e-07 29.9 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ65127.1 - 0.0015 18.6 0.2 0.0015 18.6 0.2 2.8 4 0 0 4 4 4 1 Metallo-beta-lactamase superfamily PI3_PI4_kinase PF00454.27 CDJ65128.1 - 3.2e-31 109.0 0.1 1.3e-29 103.8 0.1 2.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CDJ65128.1 - 1.6e-15 57.0 0.1 4.9e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) FeoB_associated PF12669.7 CDJ65129.1 - 0.073 13.5 1.5 6 7.4 0.0 3.1 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein SR-25 PF10500.9 CDJ65129.1 - 0.2 11.2 15.6 0.068 12.8 12.3 1.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2339 PF10101.9 CDJ65129.1 - 0.72 8.4 13.4 0.87 8.1 13.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) TauE PF01925.19 CDJ65129.1 - 2.9 7.4 6.6 3.9 7.0 6.6 1.3 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE GTP_EFTU PF00009.27 CDJ65130.1 - 1.8e-07 30.9 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain TFIIA PF03153.13 CDJ65130.1 - 0.014 15.4 13.8 0.02 14.9 13.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ65130.1 - 0.014 14.5 0.3 0.019 14.0 0.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Sporozoite_P67 PF05642.11 CDJ65130.1 - 0.39 8.8 12.1 0.48 8.4 12.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF515 PF04415.12 CDJ65130.1 - 1.4 7.3 23.4 2.4 6.5 23.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PRR18 PF15671.5 CDJ65131.1 - 0.43 10.4 5.7 0.49 10.2 5.7 1.1 1 0 0 1 1 1 0 Proline-rich protein family 18 EFG_C PF00679.24 CDJ65132.1 - 1.5e-17 63.4 0.7 2.5e-10 40.3 0.2 2.2 1 1 1 2 2 2 2 Elongation factor G C-terminus TFIIA PF03153.13 CDJ65132.1 - 0.00021 21.5 8.6 0.00022 21.3 8.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ65132.1 - 0.00093 20.1 3.0 0.0016 19.3 3.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Med15 PF09606.10 CDJ65132.1 - 0.0021 16.8 11.7 0.0023 16.7 11.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DcuA_DcuB PF03605.14 CDJ65132.1 - 0.0058 15.6 0.3 0.0081 15.1 0.3 1.2 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter RskA PF10099.9 CDJ65132.1 - 0.0069 16.7 0.7 0.012 16.0 0.7 1.4 1 1 0 1 1 1 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ65132.1 - 0.007 15.4 15.2 0.0091 15.0 15.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) MecA PF05389.12 CDJ65132.1 - 0.0077 15.9 0.4 0.0092 15.6 0.4 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) Suf PF05843.14 CDJ65132.1 - 0.0083 16.1 4.4 0.011 15.8 4.4 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) VIT PF08487.10 CDJ65132.1 - 0.023 14.9 0.9 0.047 13.9 0.9 1.5 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain YycH PF07435.11 CDJ65132.1 - 0.028 13.4 0.9 0.033 13.2 0.9 1.1 1 0 0 1 1 1 0 YycH protein UPF0560 PF10577.9 CDJ65132.1 - 0.031 12.8 4.6 0.037 12.5 4.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TERB2 PF15101.6 CDJ65132.1 - 0.044 13.8 4.7 0.064 13.3 4.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Nab6_mRNP_bdg PF10567.9 CDJ65132.1 - 0.053 13.0 0.3 0.072 12.6 0.3 1.1 1 0 0 1 1 1 0 RNA-recognition motif Presenilin PF01080.17 CDJ65132.1 - 0.13 11.0 1.3 0.16 10.7 1.3 1.1 1 0 0 1 1 1 0 Presenilin DUF3371 PF11851.8 CDJ65132.1 - 0.17 13.0 7.0 0.39 11.8 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Phosducin PF02114.16 CDJ65132.1 - 0.23 10.4 4.0 0.38 9.7 4.0 1.3 1 0 0 1 1 1 0 Phosducin DUF4175 PF13779.6 CDJ65132.1 - 0.27 9.1 13.3 0.38 8.6 13.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spt20 PF12090.8 CDJ65132.1 - 0.36 10.4 25.5 0.56 9.8 25.5 1.2 1 0 0 1 1 1 0 Spt20 family TMEM51 PF15345.6 CDJ65132.1 - 0.53 10.1 8.5 0.83 9.5 8.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF5336 PF17270.2 CDJ65132.1 - 0.59 9.7 4.8 1.2 8.8 4.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5336) MscS_TM PF12794.7 CDJ65132.1 - 0.66 8.8 2.5 1.1 8.0 2.5 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Roughex PF06020.11 CDJ65132.1 - 2.7 7.0 14.3 4.1 6.4 14.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF3464 PF11947.8 CDJ65132.1 - 3.2 7.5 5.5 5 6.9 5.5 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 mCpol PF18182.1 CDJ65133.1 - 0.13 12.6 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 minimal CRISPR polymerase domain Abhydrolase_9_N PF15420.6 CDJ65134.1 - 0.89 9.5 23.8 0.17 11.9 0.9 4.3 3 1 1 4 4 4 0 Alpha/beta-hydrolase family N-terminus SR-25 PF10500.9 CDJ65135.1 - 4.9e-05 23.1 11.0 5.8e-05 22.8 11.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BTG PF07742.12 CDJ65135.1 - 0.89 9.4 8.2 1.9 8.4 8.2 1.6 1 0 0 1 1 1 0 BTG family DUF4776 PF16003.5 CDJ65135.1 - 3.5 6.5 19.4 3.9 6.4 19.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) NOB1_Zn_bind PF08772.11 CDJ65136.1 - 0.07 13.3 0.6 0.69 10.1 1.2 1.9 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like RskA PF10099.9 CDJ65136.1 - 0.47 10.7 10.3 0.53 10.6 10.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CDK2AP PF09806.9 CDJ65137.1 - 0.0096 16.0 15.9 0.0096 16.0 15.9 4.2 4 1 0 4 4 4 1 Cyclin-dependent kinase 2-associated protein SPX PF03105.19 CDJ65137.1 - 0.068 13.1 3.2 0.85 9.5 2.8 2.7 1 1 0 1 1 1 0 SPX domain CPSF73-100_C PF11718.8 CDJ65137.1 - 0.09 12.3 3.3 0.22 11.0 3.3 1.6 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF4834 PF16118.5 CDJ65137.1 - 0.14 13.2 4.3 0.56 11.2 4.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FHIPEP PF00771.20 CDJ65137.1 - 0.33 9.3 7.0 0.2 10.1 4.0 2.0 2 0 0 2 2 2 0 FHIPEP family DUF2722 PF10846.8 CDJ65137.1 - 5.9 5.7 20.1 0.14 11.1 12.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 CDJ65137.1 - 7.5 6.5 10.4 0.58 10.2 4.4 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 HEAT PF02985.22 CDJ65138.1 - 1.3e-09 37.5 59.7 1.3e-05 25.0 0.1 15.5 15 1 0 15 15 15 4 HEAT repeat HEAT_2 PF13646.6 CDJ65138.1 - 4.5e-08 33.4 3.7 4.5e-08 33.4 3.7 11.2 6 4 6 12 12 12 5 HEAT repeats HEAT_EZ PF13513.6 CDJ65138.1 - 9.1e-07 29.3 11.1 3.3e-06 27.5 1.7 16.3 11 5 6 17 17 17 5 HEAT-like repeat Cnd1 PF12717.7 CDJ65138.1 - 1.6e-05 25.0 0.1 0.23 11.5 0.2 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CDJ65138.1 - 0.032 13.8 12.0 0.067 12.8 2.4 4.9 4 2 0 5 5 5 0 CLASP N terminal BP28CT PF08146.12 CDJ65138.1 - 0.17 11.7 2.9 2.8 7.7 0.1 3.6 3 0 0 3 3 3 0 BP28CT (NUC211) domain RTP1_C1 PF10363.9 CDJ65138.1 - 0.43 10.8 10.9 0.11 12.7 0.5 5.1 6 1 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 Tim54 PF11711.8 CDJ65138.1 - 3.1 6.5 7.3 3.6 6.3 2.4 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Ribosomal_S26e PF01283.19 CDJ65139.1 - 4.8e-49 165.3 9.2 5.8e-49 165.0 9.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e SRP19 PF01922.17 CDJ65139.1 - 0.041 14.8 0.2 0.059 14.3 0.2 1.3 1 0 0 1 1 1 0 SRP19 protein JAB PF01398.21 CDJ65140.1 - 5.8e-28 97.2 0.0 1.5e-27 95.9 0.0 1.7 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CDJ65140.1 - 6.9e-06 25.8 0.0 2.9e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CDJ65140.1 - 0.026 14.6 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) zf-CCHC PF00098.23 CDJ65142.1 - 1.2e-07 31.5 11.6 3.5e-06 26.8 2.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ65142.1 - 0.0037 17.2 0.4 0.0037 17.2 0.4 2.3 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ65142.1 - 0.0044 16.8 0.9 0.0044 16.8 0.9 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ65142.1 - 0.018 14.8 1.9 0.018 14.8 1.9 2.3 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 CDJ65142.1 - 0.15 12.4 0.1 0.45 10.8 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_4 PF14392.6 CDJ65142.1 - 0.22 11.3 6.0 0.35 10.6 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CDJ65142.1 - 0.85 10.0 8.7 2 8.8 8.7 1.6 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_5 PF14787.6 CDJ65142.1 - 2.9 7.7 10.2 1.7 8.4 1.8 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF3552 PF12072.8 CDJ65143.1 - 0.066 12.6 0.4 0.098 12.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Aminotran_1_2 PF00155.21 CDJ65144.1 - 7.3e-43 147.1 0.0 2e-41 142.4 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CDJ65144.1 - 9.9e-05 21.8 0.0 0.00029 20.3 0.0 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CDJ65144.1 - 0.001 17.7 0.0 0.0016 17.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CDJ65144.1 - 0.0065 15.8 0.0 0.033 13.5 0.0 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 CDJ65144.1 - 0.0072 15.1 0.0 0.017 13.9 0.0 1.5 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Peroxidase_ext PF11895.8 CDJ65144.1 - 0.023 14.6 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 Fungal peroxidase extension region MFS_1 PF07690.16 CDJ65145.1 - 7.4e-10 38.3 29.3 7.4e-10 38.3 29.3 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily ERGIC_N PF13850.6 CDJ65145.1 - 0.039 14.3 1.6 0.14 12.5 0.4 2.4 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1345 PF07077.11 CDJ65145.1 - 0.073 12.8 0.2 0.073 12.8 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1345) MMR_HSR1 PF01926.23 CDJ65146.1 - 8.9e-15 54.8 0.0 4.8e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase NGP1NT PF08153.12 CDJ65146.1 - 1.5e-05 25.1 0.0 3.6e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 NGP1NT (NUC091) domain FeoB_N PF02421.18 CDJ65146.1 - 0.0006 19.4 0.2 0.0017 17.9 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDJ65146.1 - 0.0089 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 CDJ65146.1 - 0.023 14.1 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF3388 PF11868.8 CDJ65146.1 - 0.094 12.0 0.0 0.18 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3388) Ribosomal_60s PF00428.19 CDJ65147.1 - 0.041 14.5 8.9 0.062 13.9 8.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein SOAR PF16533.5 CDJ65147.1 - 0.093 12.7 2.1 3.1 7.8 0.1 2.0 1 1 1 2 2 2 0 STIM1 Orai1-activating region DUF3123 PF11321.8 CDJ65147.1 - 1.8 9.3 6.2 3.5 8.3 6.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3123) Ribosomal_60s PF00428.19 CDJ65148.1 - 0.07 13.7 3.1 0.26 11.9 3.1 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1345 PF07077.11 CDJ65148.1 - 1.9 8.2 5.2 0.51 10.0 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) NitrOD5 PF11537.8 CDJ65149.1 - 0.17 12.1 0.1 0.31 11.2 0.1 1.4 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 ORC_WH_C PF18137.1 CDJ65151.1 - 0.028 14.5 6.7 0.031 14.3 6.7 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal HORMA PF02301.18 CDJ65151.1 - 0.38 10.3 4.6 0.43 10.1 4.6 1.0 1 0 0 1 1 1 0 HORMA domain V_ATPase_I PF01496.19 CDJ65151.1 - 0.46 8.3 8.5 0.47 8.3 8.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ65151.1 - 0.74 9.5 4.5 0.74 9.5 4.5 1.0 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 CDJ65151.1 - 1.4 7.9 5.6 1.4 7.9 5.6 1.0 1 0 0 1 1 1 0 CLN3 protein Endonuc_Holl PF10107.9 CDJ65151.1 - 3 7.7 11.1 3.5 7.5 11.1 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF4407 PF14362.6 CDJ65151.1 - 3.3 7.0 14.5 3.5 6.9 14.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDJ65151.1 - 3.5 6.3 11.3 3.8 6.2 11.3 1.0 1 0 0 1 1 1 0 Presenilin Sin_N PF04801.13 CDJ65151.1 - 8.2 5.5 20.0 8.6 5.4 20.0 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region Presenilin PF01080.17 CDJ65152.1 - 0.18 10.5 2.6 0.21 10.3 2.6 1.0 1 0 0 1 1 1 0 Presenilin UQ_con PF00179.26 CDJ65153.1 - 1.8e-08 34.1 0.5 1.8e-08 34.1 0.5 3.1 2 2 1 3 3 3 1 Ubiquitin-conjugating enzyme PSII_Ycf12 PF05969.11 CDJ65153.1 - 0.18 11.8 3.0 0.32 11.0 3.0 1.4 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 Dpy-30 PF05186.13 CDJ65160.1 - 1.2e-12 47.3 0.1 2.1e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Dpy-30 motif PsbI PF02532.14 CDJ65161.1 - 0.022 14.7 0.1 0.022 14.7 0.1 1.7 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) zf-C2HC_2 PF13913.6 CDJ65161.1 - 0.92 9.5 7.0 0.58 10.1 4.5 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RVT_1 PF00078.27 CDJ65162.1 - 1.7e-18 67.0 0.0 1.5e-16 60.6 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CDJ65162.1 - 5.8e-06 26.9 0.1 3.1e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Chromo PF00385.24 CDJ65163.1 - 0.059 13.3 0.7 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Nop14 PF04147.12 CDJ65165.1 - 0.0024 16.2 17.4 0.0026 16.1 17.4 1.0 1 0 0 1 1 1 1 Nop14-like family CobT PF06213.12 CDJ65165.1 - 0.023 14.1 18.6 0.028 13.8 18.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_3_Rpc31 PF11705.8 CDJ65165.1 - 0.023 14.9 22.2 0.028 14.7 22.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Connexin PF00029.19 CDJ65165.1 - 0.03 14.1 5.2 0.045 13.5 5.2 1.3 1 0 0 1 1 1 0 Connexin BUD22 PF09073.10 CDJ65165.1 - 0.036 13.4 18.5 0.044 13.1 18.5 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 CDJ65165.1 - 0.067 12.5 19.5 0.084 12.2 19.5 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 CDJ65165.1 - 0.069 12.6 18.1 0.094 12.1 18.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_Rpc4 PF05132.14 CDJ65165.1 - 0.071 13.5 4.9 0.09 13.2 4.9 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 CDJ65165.1 - 0.12 12.2 14.3 0.15 11.9 14.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4820 PF16091.5 CDJ65165.1 - 0.15 11.4 7.0 0.2 11.0 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Plasmodium_Vir PF05795.11 CDJ65165.1 - 0.16 11.4 4.0 0.14 11.5 4.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Serinc PF03348.15 CDJ65165.1 - 0.16 10.9 0.9 0.17 10.8 0.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spore_coat_CotO PF14153.6 CDJ65165.1 - 0.18 11.7 15.2 0.22 11.4 15.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO AAA_11 PF13086.6 CDJ65165.1 - 0.22 11.3 3.2 0.23 11.2 3.2 1.1 1 0 0 1 1 1 0 AAA domain PSK PF06404.12 CDJ65165.1 - 0.24 12.4 13.0 0.36 11.9 13.0 1.3 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) RPN2_C PF18004.1 CDJ65165.1 - 0.31 10.9 15.2 0.43 10.5 15.2 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SpoIIP PF07454.11 CDJ65165.1 - 0.34 10.3 8.5 0.39 10.1 8.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Mpp10 PF04006.12 CDJ65165.1 - 0.37 9.2 23.1 0.42 9.0 23.1 1.0 1 0 0 1 1 1 0 Mpp10 protein Prothymosin PF03247.14 CDJ65165.1 - 0.38 11.2 40.2 0.61 10.6 40.2 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family SDA1 PF05285.12 CDJ65165.1 - 0.39 10.1 25.1 0.43 9.9 25.1 1.0 1 0 0 1 1 1 0 SDA1 eIF-3_zeta PF05091.12 CDJ65165.1 - 0.4 9.6 5.0 0.4 9.6 5.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ65165.1 - 0.44 8.4 9.6 0.53 8.1 9.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Merozoite_SPAM PF07133.11 CDJ65165.1 - 0.46 10.5 34.8 0.56 10.2 34.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PAF PF15715.5 CDJ65165.1 - 0.5 10.9 11.7 0.69 10.5 11.7 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain TRAP_alpha PF03896.16 CDJ65165.1 - 0.64 9.2 11.7 0.83 8.8 11.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Zip PF02535.22 CDJ65165.1 - 0.69 9.1 7.3 0.79 8.9 7.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pox_Ag35 PF03286.14 CDJ65165.1 - 0.85 9.4 17.4 1.1 9.0 17.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPR3 PF03666.13 CDJ65165.1 - 0.92 8.2 9.1 0.98 8.1 9.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 CDJ65165.1 - 0.92 7.5 28.1 1.1 7.3 28.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi RNA_polI_A34 PF08208.11 CDJ65165.1 - 1 9.4 16.6 1.3 9.0 16.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF913 PF06025.12 CDJ65165.1 - 1.1 8.2 7.2 1.3 7.9 7.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 CDJ65165.1 - 1.2 7.8 5.5 1.3 7.7 5.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.11 CDJ65165.1 - 1.4 8.4 24.2 1.9 8.0 24.2 1.0 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 CDJ65165.1 - 1.5 7.0 20.8 1.8 6.8 20.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 CDJ65165.1 - 1.6 8.1 24.0 1.8 7.9 24.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PPL5 PF18168.1 CDJ65165.1 - 1.7 7.9 4.9 2 7.7 4.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Paf1 PF03985.13 CDJ65165.1 - 1.8 7.5 26.5 2 7.3 26.5 1.1 1 0 0 1 1 1 0 Paf1 CDC27 PF09507.10 CDJ65165.1 - 1.8 7.8 17.2 2.1 7.6 17.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FYDLN_acid PF09538.10 CDJ65165.1 - 1.8 9.3 17.1 2.8 8.7 17.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) VIR_N PF15912.5 CDJ65165.1 - 2.3 7.8 12.7 2.7 7.5 12.7 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Usp PF00582.26 CDJ65165.1 - 2.9 8.4 7.9 4.2 7.9 7.9 1.4 1 0 0 1 1 1 0 Universal stress protein family Hid1 PF12722.7 CDJ65165.1 - 3 5.9 4.9 2.8 5.9 4.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Afi1 PF07792.12 CDJ65165.1 - 3 8.3 10.8 4.4 7.8 10.8 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 CDJ65165.1 - 4.1 6.1 12.6 4.8 5.8 12.6 1.0 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CDJ65165.1 - 5.7 7.1 10.7 7.6 6.7 10.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2457 PF10446.9 CDJ65165.1 - 5.9 5.9 25.9 6.7 5.7 25.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFB6 PF17110.5 CDJ65165.1 - 7 6.4 11.4 9 6.0 11.4 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Raftlin PF15250.6 CDJ65165.1 - 7.6 5.2 9.7 8.7 5.0 9.7 1.0 1 0 0 1 1 1 0 Raftlin zf-CCHC PF00098.23 CDJ65167.1 - 3.5e-10 39.5 10.9 6.3e-05 22.9 1.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ65167.1 - 9.4e-05 22.0 5.9 0.0029 17.3 0.3 2.4 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger DnaJ_CXXCXGXG PF00684.19 CDJ65167.1 - 0.0021 18.3 3.8 0.0052 17.1 3.8 1.6 1 0 0 1 1 1 1 DnaJ central domain zf-CCHC_2 PF13696.6 CDJ65167.1 - 0.004 17.0 0.8 0.004 17.0 0.8 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ65167.1 - 0.015 15.3 2.9 1.2 9.1 0.2 2.4 1 1 1 2 2 2 0 Zinc knuckle Cofac_haem_bdg PF04187.13 CDJ65167.1 - 0.033 14.2 0.4 0.071 13.1 0.4 1.5 1 1 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Retrotrans_gag PF03732.17 CDJ65167.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.7 1 1 1 2 2 2 0 Retrotransposon gag protein zf-CCHC_4 PF14392.6 CDJ65167.1 - 0.13 12.0 7.6 3.1 7.6 0.6 3.2 3 0 0 3 3 3 0 Zinc knuckle eIF3g PF12353.8 CDJ65167.1 - 9.4 6.7 8.0 31 5.0 1.6 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G DUF2722 PF10846.8 CDJ65170.1 - 0.0011 18.1 5.2 0.0011 18.1 5.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ65170.1 - 0.031 13.9 21.2 0.049 13.2 13.8 2.1 2 0 0 2 2 2 0 Spt20 family Macoilin PF09726.9 CDJ65170.1 - 0.12 10.9 8.5 0.16 10.5 8.5 1.2 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CDJ65170.1 - 0.26 11.2 24.1 1.8 8.5 16.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Phostensin_N PF13916.6 CDJ65170.1 - 0.33 11.3 7.4 8 6.9 3.3 2.5 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal TERB2 PF15101.6 CDJ65170.1 - 0.61 10.1 9.2 1.8 8.6 5.6 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4834 PF16118.5 CDJ65170.1 - 0.75 10.8 7.4 0.79 10.7 3.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) GTA_holin_3TM PF11351.8 CDJ65170.1 - 1.2 9.7 10.1 3.5 8.2 2.9 2.2 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release RR_TM4-6 PF06459.12 CDJ65170.1 - 2.4 7.9 7.7 0.48 10.2 3.7 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 CDJ65170.1 - 3.8 7.4 11.7 1.5 8.7 6.7 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RskA PF10099.9 CDJ65171.1 - 7.1e-05 23.2 1.2 9e-05 22.8 1.2 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ65171.1 - 0.0006 19.5 1.5 0.00086 19.0 1.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ65171.1 - 0.07 13.3 2.7 0.091 12.9 2.7 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Spt20 PF12090.8 CDJ65171.1 - 0.16 11.6 8.4 0.2 11.3 8.4 1.1 1 0 0 1 1 1 0 Spt20 family Dehydrin PF00257.19 CDJ65171.1 - 0.89 10.1 11.7 1.6 9.3 11.7 1.6 1 1 0 1 1 1 0 Dehydrin TPR_1 PF00515.28 CDJ65172.1 - 7.7e-08 31.8 18.6 0.00036 20.2 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ65172.1 - 3.5e-07 29.8 17.1 0.014 15.4 2.6 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ65172.1 - 8.5e-06 25.4 9.4 0.039 14.0 0.2 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat PH_11 PF15413.6 CDJ65172.1 - 0.11 12.9 0.3 0.11 12.9 0.3 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain TPR_8 PF13181.6 CDJ65172.1 - 0.13 12.5 14.8 6.6 7.2 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat YafQ_toxin PF15738.5 CDJ65172.1 - 2.3 8.6 5.3 0.73 10.2 0.4 2.6 2 1 1 3 3 3 0 Bacterial toxin of type II toxin-antitoxin system, YafQ Abi_2 PF07751.11 CDJ65172.1 - 6.2 7.0 6.5 4.9 7.4 0.0 2.6 3 0 0 3 3 3 0 Abi-like protein Lebercilin PF15619.6 CDJ65173.1 - 0.0055 16.4 26.6 0.0055 16.4 26.6 3.8 3 1 1 4 4 4 2 Ciliary protein causing Leber congenital amaurosis disease Fmp27_WPPW PF10359.9 CDJ65173.1 - 0.006 15.5 0.7 0.006 15.5 0.7 3.2 2 1 1 3 3 3 1 RNA pol II promoter Fmp27 protein domain Ribosomal_60s PF00428.19 CDJ65173.1 - 0.037 14.6 3.0 0.037 14.6 3.0 4.7 3 1 1 4 4 4 0 60s Acidic ribosomal protein Peptidase_M24 PF00557.24 CDJ65174.1 - 0.00028 20.6 0.0 0.00028 20.6 0.0 2.5 2 1 0 2 2 2 1 Metallopeptidase family M24 TFIIA PF03153.13 CDJ65174.1 - 0.5 10.3 25.8 0.8 9.6 25.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4614 PF15391.6 CDJ65174.1 - 4.5 7.2 16.2 0.094 12.7 6.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Sporozoite_P67 PF05642.11 CDJ65176.1 - 0.023 12.8 2.7 0.028 12.5 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SR-25 PF10500.9 CDJ65176.1 - 0.052 13.2 10.5 0.065 12.8 10.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ACC_central PF08326.12 CDJ65176.1 - 0.054 11.7 0.5 0.053 11.7 0.5 1.0 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region IMUP PF15761.5 CDJ65176.1 - 0.11 13.2 12.5 0.19 12.4 12.5 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Roughex PF06020.11 CDJ65176.1 - 0.22 10.6 2.7 0.27 10.3 2.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Med3 PF11593.8 CDJ65176.1 - 0.23 10.6 9.4 0.28 10.3 9.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF775 PF05603.12 CDJ65176.1 - 0.31 10.6 4.3 0.36 10.3 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Lin-8 PF03353.15 CDJ65176.1 - 0.89 9.1 4.9 1.1 8.8 4.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CDJ65176.1 - 1.1 8.8 5.9 1.3 8.6 5.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF1180 PF06679.12 CDJ65176.1 - 2.1 8.7 6.4 1.6 9.1 4.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Dehydrin PF00257.19 CDJ65176.1 - 5.3 7.6 7.8 9.7 6.7 7.8 1.4 1 0 0 1 1 1 0 Dehydrin PCI PF01399.27 CDJ65177.1 - 9.6e-11 42.1 1.6 1.1e-10 42.0 0.2 1.8 2 1 0 2 2 2 1 PCI domain SARAF PF06682.12 CDJ65177.1 - 0.016 14.9 0.8 0.021 14.5 0.8 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis hGDE_central PF14702.6 CDJ65177.1 - 0.034 13.8 0.4 0.057 13.1 0.4 1.3 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme Spt20 PF12090.8 CDJ65177.1 - 0.043 13.4 10.6 0.06 13.0 10.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF1645 PF07816.11 CDJ65177.1 - 0.044 14.4 0.5 0.044 14.4 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF1699 PF08004.11 CDJ65177.1 - 0.27 10.9 1.3 0.8 9.4 0.1 2.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1699) SR-25 PF10500.9 CDJ65177.1 - 2.3 7.8 14.4 0.35 10.4 9.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S8 PF00082.22 CDJ65178.1 - 2e-08 33.8 0.1 2e-08 33.8 0.1 2.1 2 1 1 3 3 3 1 Subtilase family Shadoo PF14999.6 CDJ65178.1 - 0.047 13.8 5.8 0.1 12.7 5.8 1.6 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Cu-binding_MopE PF11617.8 CDJ65178.1 - 0.067 13.4 0.3 0.14 12.3 0.3 1.6 1 0 0 1 1 1 0 Putative metal-binding motif Neur_chan_memb PF02932.16 CDJ65178.1 - 0.11 12.5 0.5 0.12 12.4 0.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Vfa1 PF08432.10 CDJ65178.1 - 4.3 7.6 22.0 5.7 7.2 22.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CPSF100_C PF13299.6 CDJ65178.1 - 5.6 7.1 12.1 8.8 6.5 12.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PIEZO PF15917.5 CDJ65178.1 - 6.9 6.1 11.8 9 5.7 11.8 1.1 1 0 0 1 1 1 0 Piezo NPR3 PF03666.13 CDJ65178.1 - 7.8 5.2 14.2 9.3 4.9 14.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_S49_N PF08496.10 CDJ65178.1 - 7.9 6.5 14.6 12 6.0 14.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Zip PF02535.22 CDJ65178.1 - 8.6 5.5 7.2 10 5.2 7.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S8 PF00082.22 CDJ65179.1 - 8.5e-24 84.3 9.9 7.4e-21 74.7 7.1 3.3 3 1 0 3 3 3 2 Subtilase family RskA PF10099.9 CDJ65179.1 - 0.0019 18.5 0.3 0.0019 18.5 0.3 3.9 2 1 1 4 4 4 2 Anti-sigma-K factor rskA Filament_head PF04732.14 CDJ65179.1 - 3.1 8.7 56.8 3.6 8.5 18.4 4.4 4 0 0 4 4 4 0 Intermediate filament head (DNA binding) region EphA2_TM PF14575.6 CDJ65179.1 - 4.7 8.2 7.5 1.1e+02 3.8 0.0 3.9 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Vps16_C PF04840.12 CDJ65180.1 - 1.8e-39 135.7 0.0 7e-39 133.7 0.0 2.0 1 1 0 1 1 1 1 Vps16, C-terminal region Med15 PF09606.10 CDJ65180.1 - 2 7.0 29.7 1.7 7.2 15.5 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.13 CDJ65180.1 - 3.2 8.4 19.6 5.4 7.6 2.5 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ65180.1 - 3.7 7.1 29.8 0.34 10.5 19.3 2.2 2 0 0 2 2 2 0 Spt20 family LCCL PF03815.19 CDJ65181.1 - 3.4e-09 36.7 0.1 3.4e-09 36.7 0.1 1.9 2 0 0 2 2 2 1 LCCL domain Rxt3 PF08642.10 CDJ65181.1 - 0.027 15.2 0.7 0.29 11.9 0.0 2.7 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 Sin_N PF04801.13 CDJ65182.1 - 0.003 16.8 43.5 0.014 14.6 16.1 3.2 3 0 0 3 3 3 2 Sin-like protein conserved region F-box PF00646.33 CDJ65182.1 - 0.0069 16.2 0.1 0.025 14.4 0.1 2.0 1 0 0 1 1 1 1 F-box domain SARAF PF06682.12 CDJ65182.1 - 0.0078 15.9 2.0 0.0078 15.9 2.0 2.8 3 0 0 3 3 3 2 SOCE-associated regulatory factor of calcium homoeostasis DUF572 PF04502.13 CDJ65182.1 - 5.2 6.6 29.2 2.1 7.9 16.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) ANTH PF07651.16 CDJ65185.1 - 0.1 11.5 0.9 0.19 10.7 0.9 1.3 1 0 0 1 1 1 0 ANTH domain Velvet PF11754.8 CDJ65185.1 - 0.27 11.1 9.8 0.062 13.2 6.3 1.6 2 0 0 2 2 2 0 Velvet factor Herpes_pp85 PF04637.12 CDJ65185.1 - 0.74 8.2 2.2 1.1 7.6 2.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) FAM199X PF15814.5 CDJ65185.1 - 0.83 8.7 12.9 0.036 13.1 3.9 2.1 2 0 0 2 2 2 0 Protein family FAM199X TCP PF03634.13 CDJ65185.1 - 2 8.9 11.2 0.064 13.8 4.3 2.0 3 0 0 3 3 3 0 TCP family transcription factor SR-25 PF10500.9 CDJ65185.1 - 3 7.4 22.8 1.4 8.5 19.7 2.0 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ65185.1 - 7.6 6.4 10.8 1 9.3 5.8 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SUIM_assoc PF16619.5 CDJ65187.1 - 0.43 10.7 16.3 0.064 13.3 2.8 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Ten_N PF06484.12 CDJ65188.1 - 7.8 6.3 45.6 10 5.9 45.6 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region tRNA-synt_1d PF00750.19 CDJ65189.1 - 3.2e-50 171.0 5.1 2e-49 168.4 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (R) Ribosomal_60s PF00428.19 CDJ65189.1 - 0.033 14.8 2.1 0.033 14.8 2.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1980 PF09323.10 CDJ65189.1 - 0.039 13.9 3.9 0.061 13.2 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Connexin PF00029.19 CDJ65189.1 - 0.11 12.2 5.1 0.19 11.5 5.1 1.4 1 0 0 1 1 1 0 Connexin DUF429 PF04250.13 CDJ65189.1 - 0.2 11.5 22.2 0.46 10.2 6.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF429) DDHD PF02862.17 CDJ65189.1 - 0.39 10.8 13.6 5.2 7.2 12.2 2.1 2 0 0 2 2 2 0 DDHD domain RNA_pol_Rpc4 PF05132.14 CDJ65189.1 - 0.66 10.4 15.8 1.4 9.3 12.6 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 CCDC53 PF10152.9 CDJ65189.1 - 0.97 9.8 15.3 15 6.0 14.0 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF4834 PF16118.5 CDJ65189.1 - 1.5 9.8 15.6 0.53 11.3 12.7 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) Folate_carrier PF01770.18 CDJ65189.1 - 3 6.5 5.0 3.9 6.1 5.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier V_ATPase_I PF01496.19 CDJ65189.1 - 5.1 4.9 12.6 1.3 6.8 10.0 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family AIF_C PF14721.6 CDJ65189.1 - 7.7 6.9 13.2 1.7 9.0 8.4 2.0 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SpoIIP PF07454.11 CDJ65189.1 - 7.8 5.9 15.5 18 4.7 15.5 1.6 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF3006 PF11213.8 CDJ65193.1 - 1.6e-06 28.2 0.5 3.7e-06 27.1 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3006) CHS5_N PF16892.5 CDJ65193.1 - 1.8e-05 24.5 0.1 1.8e-05 24.5 0.1 1.5 2 0 0 2 2 2 1 Chitin biosynthesis protein CHS5 N-terminus Dynactin_p62 PF05502.13 CDJ65194.1 - 5.6e-11 41.9 17.0 7.8e-09 34.8 6.9 3.3 3 0 0 3 3 3 3 Dynactin p62 family DUF3665 PF12427.8 CDJ65194.1 - 0.28 10.9 0.9 7 6.4 0.2 2.4 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase FlxA PF14282.6 CDJ65194.1 - 2.3 8.3 10.8 7.1 6.7 10.8 1.8 1 0 0 1 1 1 0 FlxA-like protein Ribosomal_L18A PF01775.17 CDJ65195.1 - 7.7e-36 122.8 0.0 9.6e-36 122.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Spt20 PF12090.8 CDJ65196.1 - 0.00093 18.9 42.5 0.0091 15.6 11.1 2.2 2 0 0 2 2 2 2 Spt20 family Med3 PF11593.8 CDJ65196.1 - 0.0041 16.4 5.0 0.0041 16.4 5.0 3.4 3 0 0 3 3 2 1 Mediator complex subunit 3 fungal EPL1 PF10513.9 CDJ65196.1 - 0.013 15.9 11.2 0.049 14.0 0.9 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF2722 PF10846.8 CDJ65196.1 - 0.026 13.5 41.0 0.39 9.6 19.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SPX PF03105.19 CDJ65196.1 - 0.087 12.7 20.5 0.056 13.3 4.0 2.7 2 1 0 2 2 2 0 SPX domain CPSF100_C PF13299.6 CDJ65196.1 - 0.18 12.0 11.2 1.9 8.6 1.0 3.0 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Sin_N PF04801.13 CDJ65196.1 - 0.96 8.6 18.0 1.1 8.3 6.9 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region Roughex PF06020.11 CDJ65196.1 - 1 8.4 21.7 0.47 9.5 5.7 2.4 2 0 0 2 2 2 0 Drosophila roughex protein NST1 PF13945.6 CDJ65196.1 - 1.3 9.1 19.3 1.5 8.9 6.7 2.5 2 0 0 2 2 2 0 Salt tolerance down-regulator Peptidase_S49_N PF08496.10 CDJ65196.1 - 3.6 7.7 7.2 12 6.0 1.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SLC12 PF03522.15 CDJ65196.1 - 3.7 6.5 11.3 1.8 7.5 2.8 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ65196.1 - 4.6 6.7 27.6 3.2 7.2 7.1 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ65196.1 - 5.7 6.8 57.3 2.6 8.0 20.4 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 CDJ65196.1 - 6.6 5.4 8.2 7.9 5.1 1.0 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 PRC2_HTH_1 PF18118.1 CDJ65196.1 - 6.6 7.6 7.6 39 5.1 2.5 2.6 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain DUF4614 PF15391.6 CDJ65197.1 - 0.65 10.0 28.5 1 9.4 28.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) BAF1_ABF1 PF04684.13 CDJ65197.1 - 6.6 5.7 15.0 7.4 5.5 15.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Yip1 PF04893.17 CDJ65198.1 - 4.3e-10 39.6 14.1 6.1e-10 39.1 14.1 1.3 1 0 0 1 1 1 1 Yip1 domain Ribosomal_60s PF00428.19 CDJ65198.1 - 1.1 9.9 5.9 0.22 12.1 2.2 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein SR-25 PF10500.9 CDJ65198.1 - 1.8 8.1 10.3 2.6 7.6 10.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 CDJ65198.1 - 7.4 7.5 10.9 19 6.1 1.3 2.2 2 0 0 2 2 2 0 Chorion family 2 DUF4329 PF14220.6 CDJ65199.1 - 0.28 11.2 3.4 0.29 11.1 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) SR-25 PF10500.9 CDJ65199.1 - 3.8 7.1 13.4 5.1 6.6 13.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SMC_N PF02463.19 CDJ65200.1 - 4.3e-10 39.4 0.0 9e-10 38.4 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF3458_C PF17432.2 CDJ65201.1 - 0.00013 21.5 0.0 0.00014 21.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Med3 PF11593.8 CDJ65202.1 - 0.0062 15.8 18.2 0.0079 15.4 18.2 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Neur_chan_memb PF02932.16 CDJ65202.1 - 0.18 11.8 6.4 0.26 11.3 6.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ65202.1 - 0.37 10.7 11.5 0.48 10.4 11.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF5423 PF17461.2 CDJ65202.1 - 1.1 8.0 11.3 1.7 7.4 11.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5423) CDT1_C PF16679.5 CDJ65202.1 - 1.2 9.7 11.3 0.91 10.0 3.9 2.5 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Hamartin PF04388.12 CDJ65202.1 - 2.1 6.9 10.4 2.4 6.7 10.4 1.0 1 0 0 1 1 1 0 Hamartin protein Presenilin PF01080.17 CDJ65202.1 - 2.8 6.6 11.5 4.2 6.0 11.5 1.4 1 0 0 1 1 1 0 Presenilin PARM PF17061.5 CDJ65202.1 - 3.1 7.9 17.5 4.3 7.4 17.5 1.2 1 0 0 1 1 1 0 PARM PI3K_1B_p101 PF10486.9 CDJ65202.1 - 4.8 4.8 10.7 5.6 4.6 10.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 CDJ65202.1 - 4.9 5.6 13.7 5.3 5.5 13.7 1.1 1 0 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 CDJ65202.1 - 5.9 6.6 11.8 8.9 6.0 11.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 CDJ65202.1 - 6.5 5.5 12.1 7.5 5.3 12.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAT1 PF09770.9 CDJ65202.1 - 6.6 4.9 15.8 8.1 4.6 15.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.13 CDJ65202.1 - 8.2 5.9 13.2 12 5.3 13.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_C1 PF00112.23 CDJ65205.1 - 7e-06 26.3 0.0 7.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease CPBP PF02517.16 CDJ65206.1 - 3.6e-08 33.7 1.1 1.7e-07 31.5 1.1 2.3 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease EcsB PF05975.12 CDJ65206.1 - 0.037 12.9 0.1 0.061 12.2 0.1 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB PT-VENN PF04829.13 CDJ65206.1 - 1.5 8.9 5.5 0.7 10.0 0.7 2.4 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Peptidase_M14 PF00246.24 CDJ65207.1 - 5.1e-10 39.6 0.0 1.5e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase DUF5532 PF17673.1 CDJ65207.1 - 0.09 12.8 0.2 0.57 10.3 0.0 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5532) MOZART2 PF12926.7 CDJ65207.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Arf PF00025.21 CDJ65208.1 - 2.9e-66 222.2 0.0 3.3e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CDJ65208.1 - 4.9e-12 45.7 0.5 2.5e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CDJ65208.1 - 1.9e-11 44.2 0.0 2.7e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ65208.1 - 1.1e-09 38.1 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDJ65208.1 - 1.6e-08 34.2 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ65208.1 - 2.2e-06 27.7 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ65208.1 - 7.1e-05 22.3 0.0 9.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDJ65208.1 - 0.015 14.8 0.0 0.057 12.9 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CDJ65208.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PPK2 PF03976.14 CDJ65208.1 - 0.21 11.1 0.1 0.36 10.3 0.1 1.4 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) CNDH2_C PF16858.5 CDJ65209.1 - 2.1e-11 44.2 0.6 4.6e-11 43.1 0.6 1.6 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 CDJ65209.1 - 2e-05 24.8 0.0 2e-05 24.8 0.0 2.8 3 1 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Pyr_redox_2 PF07992.14 CDJ65211.1 - 8.2e-35 120.5 0.1 3.7e-26 92.1 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ65211.1 - 3.1e-12 46.9 0.0 5e-10 39.8 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Band_7 PF01145.25 CDJ65211.1 - 0.036 14.1 0.6 0.068 13.2 0.6 1.5 1 0 0 1 1 1 0 SPFH domain / Band 7 family NAD_binding_7 PF13241.6 CDJ65211.1 - 0.1 13.0 0.1 0.48 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 CDJ65211.1 - 0.11 12.8 7.9 0.3 11.3 0.0 3.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CDJ65211.1 - 0.23 10.1 2.0 1.9 7.1 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein UCH PF00443.29 CDJ65212.1 - 8.4e-40 136.9 0.0 2.8e-39 135.2 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ65212.1 - 3.8e-14 53.0 0.0 2e-05 24.3 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 CDJ65212.1 - 0.0037 17.0 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal FliM PF02154.15 CDJ65212.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Ribosomal_60s PF00428.19 CDJ65212.1 - 0.026 15.1 0.3 0.026 15.1 0.3 9.5 7 2 2 9 9 9 0 60s Acidic ribosomal protein TMEM100 PF16311.5 CDJ65213.1 - 0.085 12.4 2.4 7.2 6.2 0.4 2.6 1 1 0 2 2 2 0 Transmembrane protein 100 Peptidase_M8 PF01457.16 CDJ65213.1 - 0.33 9.6 1.4 0.52 8.9 1.4 1.2 1 0 0 1 1 1 0 Leishmanolysin DUF3185 PF11381.8 CDJ65213.1 - 0.52 10.4 4.3 4 7.5 2.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) Glycophorin_A PF01102.18 CDJ65213.1 - 1.5 9.1 3.9 0.8 10.0 0.1 2.3 2 0 0 2 2 2 0 Glycophorin A GDP_Man_Dehyd PF16363.5 CDJ65214.1 - 1.4e-116 389.6 0.0 1.3e-114 383.0 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDJ65214.1 - 9.3e-65 218.4 0.0 1.2e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CDJ65214.1 - 7e-09 35.2 0.0 9.4e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CDJ65214.1 - 0.003 16.7 0.0 0.0062 15.7 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CDJ65214.1 - 0.039 13.5 0.0 0.071 12.6 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family p31comet PF06581.12 CDJ65216.1 - 0.089 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding His_Phos_2 PF00328.22 CDJ65217.1 - 6.3e-08 32.4 16.4 9.6e-06 25.2 0.0 3.9 4 0 0 4 4 4 3 Histidine phosphatase superfamily (branch 2) eIF-3_zeta PF05091.12 CDJ65217.1 - 1.9 7.4 13.8 5.9 5.7 14.1 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ELMO_CED12 PF04727.13 CDJ65218.1 - 7.9e-27 94.5 0.0 1.2e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family RAP PF08373.10 CDJ65221.1 - 6.6e-14 51.7 0.0 1.4e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 RAP domain Androgen_recep PF02166.16 CDJ65221.1 - 0.0015 17.4 15.5 0.0025 16.7 7.1 2.2 2 0 0 2 2 2 2 Androgen receptor TFIIA PF03153.13 CDJ65221.1 - 0.029 14.4 24.1 0.2 11.6 16.0 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ65221.1 - 0.048 13.3 27.5 0.22 11.1 1.0 2.2 2 0 0 2 2 2 0 Spt20 family LIM_bind PF01803.16 CDJ65221.1 - 0.16 11.5 6.1 5.8 6.4 0.0 2.3 2 0 0 2 2 2 0 LIM-domain binding protein Med15 PF09606.10 CDJ65221.1 - 0.3 9.7 25.7 0.47 9.1 17.0 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CDJ65221.1 - 0.34 9.8 21.4 0.58 9.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF2973 PF11189.8 CDJ65221.1 - 3.7 7.7 5.1 23 5.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Suf PF05843.14 CDJ65221.1 - 4.7 7.1 10.4 7.8 6.4 5.5 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3408 PF11888.8 CDJ65221.1 - 6.3 6.9 10.9 5.4 7.2 7.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) RskA PF10099.9 CDJ65222.1 - 2.9e-05 24.4 6.1 2.9e-05 24.4 6.1 5.9 2 2 2 4 4 3 2 Anti-sigma-K factor rskA ESM4 PF15952.5 CDJ65222.1 - 0.0033 17.9 6.2 0.0033 17.9 6.2 3.1 3 0 0 3 3 3 1 Enhancer of split M4 family SR-25 PF10500.9 CDJ65222.1 - 0.0064 16.1 2.0 0.0064 16.1 2.0 5.4 5 1 0 5 5 3 1 Nuclear RNA-splicing-associated protein DUF2052 PF09747.9 CDJ65222.1 - 0.0077 16.4 18.5 0.088 12.9 4.8 2.7 3 0 0 3 3 3 2 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 CDJ65222.1 - 0.15 11.7 11.6 1.8 8.3 0.9 3.3 3 0 0 3 3 3 0 FAM176 family DUF572 PF04502.13 CDJ65222.1 - 0.19 11.3 18.3 0.047 13.3 9.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4611 PF15387.6 CDJ65222.1 - 0.3 11.3 12.9 0.11 12.7 1.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF4471 PF14740.6 CDJ65222.1 - 1.1 8.4 4.9 1.2 8.3 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Radial_spoke PF04712.12 CDJ65222.1 - 2.2 7.2 14.3 0.31 9.9 3.1 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein DUF1980 PF09323.10 CDJ65222.1 - 2.2 8.2 4.4 0.83 9.5 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) TFB6 PF17110.5 CDJ65222.1 - 2.2 8.0 9.4 1.9 8.2 3.4 2.4 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH PIEZO PF15917.5 CDJ65222.1 - 2.9 7.3 14.6 18 4.7 10.8 2.6 2 0 0 2 2 2 0 Piezo Ofd1_CTDD PF10637.9 CDJ65222.1 - 3.1 7.1 9.4 6.7 6.0 3.4 2.3 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term TRAP_alpha PF03896.16 CDJ65222.1 - 3.7 6.7 9.3 1.9 7.6 1.2 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SpoIIP PF07454.11 CDJ65222.1 - 4 6.8 12.7 0.016 14.7 1.3 2.4 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) SDA1 PF05285.12 CDJ65222.1 - 4.7 6.5 19.3 6.7 6.0 1.1 3.3 3 0 0 3 3 3 0 SDA1 MecA PF05389.12 CDJ65222.1 - 9.1 5.8 11.5 0.35 10.5 2.8 2.6 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) Glyco_hydro_3_C PF01915.22 CDJ65223.1 - 0.71 9.8 3.7 0.88 9.5 3.7 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain DUF2070 PF09843.9 CDJ65224.1 - 6.2 5.0 13.4 7.8 4.6 13.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2722 PF10846.8 CDJ65225.1 - 0.0059 15.6 1.4 0.0059 15.6 1.4 4.2 4 0 0 4 4 4 2 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ65225.1 - 0.27 11.5 22.3 0.13 12.6 1.4 4.3 3 1 0 4 4 4 0 Anti-sigma-K factor rskA EGF_MSP1_1 PF12946.7 CDJ65225.1 - 0.39 10.8 4.8 1.2 9.3 4.8 1.9 1 0 0 1 1 1 0 MSP1 EGF domain 1 FlgH PF02107.16 CDJ65225.1 - 4.8 6.8 6.9 3.2 7.3 0.0 2.6 3 0 0 3 3 3 0 Flagellar L-ring protein SR-25 PF10500.9 CDJ65226.1 - 1.6 8.3 18.4 2.5 7.6 18.4 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein IHABP4_N PF16174.5 CDJ65226.1 - 2.9 8.4 17.6 3.4 8.2 17.6 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal ORC6 PF05460.13 CDJ65226.1 - 7.3 5.8 13.2 8.8 5.5 13.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SR-25 PF10500.9 CDJ65227.1 - 0.00057 19.6 1.9 0.00057 19.6 1.9 4.1 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein CDK2AP PF09806.9 CDJ65227.1 - 0.019 15.0 3.6 0.019 15.0 3.6 4.5 4 1 0 4 4 4 0 Cyclin-dependent kinase 2-associated protein CYSTM PF12734.7 CDJ65227.1 - 0.025 14.9 3.6 0.025 14.9 3.6 4.5 5 0 0 5 5 5 0 Cysteine-rich TM module stress tolerance YL1 PF05764.13 CDJ65227.1 - 0.24 11.5 9.4 0.028 14.5 2.0 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Mid2 PF04478.12 CDJ65227.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.2 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor GT87 PF09594.10 CDJ65227.1 - 1.7 8.3 17.0 0.044 13.5 9.2 2.1 3 0 0 3 3 3 0 Glycosyltransferase family 87 Spt20 PF12090.8 CDJ65227.1 - 2.4 7.7 18.5 0.075 12.6 12.0 1.7 2 0 0 2 2 2 0 Spt20 family TMEM154 PF15102.6 CDJ65227.1 - 3.4 7.6 0.0 3.4 7.6 0.0 3.5 4 1 0 4 4 4 0 TMEM154 protein family Inj_translocase PF16928.5 CDJ65227.1 - 8.3 5.8 15.1 48 3.3 13.6 2.2 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome Spt20 PF12090.8 CDJ65229.1 - 0.0052 16.4 28.6 0.038 13.6 17.6 2.4 2 0 0 2 2 2 2 Spt20 family Eapp_C PF10238.9 CDJ65229.1 - 0.7 10.0 8.8 0.57 10.3 3.0 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein Suf PF05843.14 CDJ65229.1 - 6.6 6.6 16.0 9.4 6.1 1.2 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TCP PF03634.13 CDJ65231.1 - 0.00042 20.9 3.1 0.00081 20.0 3.1 1.5 1 0 0 1 1 1 1 TCP family transcription factor DUF3464 PF11947.8 CDJ65231.1 - 0.00083 19.1 2.6 0.0014 18.4 2.6 1.3 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 DUF2722 PF10846.8 CDJ65231.1 - 0.0015 17.5 10.5 0.0015 17.5 10.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ65231.1 - 0.0095 15.6 19.1 0.015 14.9 19.1 1.3 1 0 0 1 1 1 1 Spt20 family Presenilin PF01080.17 CDJ65231.1 - 0.053 12.3 1.6 0.059 12.1 1.6 1.2 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ65231.1 - 0.061 12.3 3.6 0.076 12.0 3.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ65231.1 - 0.17 11.9 6.3 0.28 11.2 6.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4834 PF16118.5 CDJ65231.1 - 0.76 10.8 8.0 0.59 11.1 5.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RLL PF10036.9 CDJ65231.1 - 1 9.2 10.4 1.4 8.7 10.4 1.1 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein SR-25 PF10500.9 CDJ65231.1 - 1.2 8.7 19.2 5.8 6.5 12.8 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CPSF100_C PF13299.6 CDJ65231.1 - 1.3 9.2 5.4 2.2 8.4 5.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PAT1 PF09770.9 CDJ65231.1 - 1.6 6.9 13.6 2.1 6.5 13.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Roughex PF06020.11 CDJ65231.1 - 3.3 6.7 8.0 4.7 6.2 8.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Topoisom_I_N PF02919.15 CDJ65232.1 - 4.8e-84 281.1 3.5 2.5e-83 278.8 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 CDJ65232.1 - 1.5e-76 256.7 3.5 1e-46 159.1 0.5 2.6 1 1 1 2 2 2 2 Eukaryotic DNA topoisomerase I, catalytic core Sas10_Utp3 PF04000.15 CDJ65234.1 - 1.4e-07 32.1 0.0 1.4e-07 32.1 0.0 3.3 3 2 0 3 3 3 1 Sas10/Utp3/C1D family SR-25 PF10500.9 CDJ65234.1 - 1.6e-06 27.9 22.1 3.1e-06 27.0 22.1 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2294 PF10057.9 CDJ65234.1 - 0.37 10.9 5.2 0.71 10.0 5.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) RAP1 PF07218.11 CDJ65234.1 - 0.4 8.9 15.5 0.52 8.5 15.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_60s PF00428.19 CDJ65234.1 - 1.8 9.2 24.8 0.6 10.7 15.2 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein PI3K_1B_p101 PF10486.9 CDJ65234.1 - 3.2 5.4 28.2 0.59 7.9 22.3 1.9 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4698 PF15769.5 CDJ65234.1 - 3.4 6.6 19.8 5 6.1 19.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) NAM-associated PF14303.6 CDJ65234.1 - 3.9 8.2 23.0 0.53 11.0 18.0 2.0 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain SPX PF03105.19 CDJ65234.1 - 5.5 6.8 26.1 19 5.0 26.1 1.9 1 1 0 1 1 1 0 SPX domain Miga PF10265.9 CDJ65234.1 - 8.9 5.2 13.5 16 4.3 13.5 1.4 1 0 0 1 1 1 0 Mitoguardin SWIB PF02201.18 CDJ65235.1 - 1.1e-13 50.8 0.1 3.6e-13 49.2 0.1 1.9 1 0 0 1 1 1 1 SWIB/MDM2 domain PP2C PF00481.21 CDJ65235.1 - 2e-07 30.9 4.8 9.2e-05 22.2 0.1 4.3 3 2 2 5 5 5 2 Protein phosphatase 2C FAM76 PF16046.5 CDJ65235.1 - 0.0069 15.8 3.1 0.0069 15.8 3.1 6.3 4 1 0 5 5 5 1 FAM76 protein TFIIA PF03153.13 CDJ65235.1 - 0.0075 16.3 23.1 0.0075 16.3 23.1 6.2 2 1 4 6 6 6 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ65236.1 - 0.03 13.9 18.0 0.026 14.1 18.0 1.1 1 0 0 1 1 1 0 Spt20 family NKAP PF15692.5 CDJ65236.1 - 0.16 12.7 5.4 0.25 12.1 5.4 1.6 1 1 0 1 1 1 0 NF-kappa-B-activating protein TMEM208_SND2 PF05620.11 CDJ65236.1 - 2 8.2 4.5 2 8.2 4.5 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 TFIIA PF03153.13 CDJ65236.1 - 2.2 8.2 18.7 2.1 8.2 18.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4661 PF15576.6 CDJ65236.1 - 3.1 7.7 5.7 3.2 7.6 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Presenilin PF01080.17 CDJ65236.1 - 7.7 5.2 7.3 7.4 5.2 7.3 1.0 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 CDJ65237.1 - 2.2e-07 31.4 1.8 0.0016 19.2 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Hid1 PF12722.7 CDJ65238.1 - 0.0089 14.2 17.3 0.011 13.9 17.3 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein DUF572 PF04502.13 CDJ65238.1 - 0.0099 15.5 16.1 0.011 15.3 16.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF4045 PF13254.6 CDJ65238.1 - 0.017 14.8 16.9 0.018 14.7 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SMYLE_N PF18615.1 CDJ65238.1 - 0.053 13.1 15.0 0.079 12.5 15.0 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain GAGA_bind PF06217.12 CDJ65238.1 - 0.089 13.1 17.1 0.1 12.9 17.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family MRP-S27 PF10037.9 CDJ65238.1 - 0.58 9.0 25.9 0.7 8.7 25.9 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 FapA PF03961.13 CDJ65238.1 - 0.7 8.4 18.6 0.9 8.1 18.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CCSAP PF15748.5 CDJ65238.1 - 1.5 8.9 30.0 2.5 8.2 30.0 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PA26 PF04636.13 CDJ65238.1 - 2.8 6.8 19.6 3.8 6.3 19.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3295 PF11702.8 CDJ65238.1 - 3.8 6.7 25.5 5.5 6.2 25.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Presenilin PF01080.17 CDJ65238.1 - 5.6 5.6 32.6 9.9 4.8 32.6 1.3 1 0 0 1 1 1 0 Presenilin Cullin_Nedd8 PF10557.9 CDJ65239.1 - 4.4e-14 52.3 0.0 4.8e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Cullin protein neddylation domain SNAP PF14938.6 CDJ65241.1 - 1.5e-47 162.4 29.9 6.8e-28 97.9 8.3 2.0 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TFIIA PF03153.13 CDJ65241.1 - 0.74 9.7 10.1 0.83 9.6 8.9 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Profilin PF00235.19 CDJ65244.1 - 0.0022 18.3 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 Profilin Na_H_antiport_3 PF07399.11 CDJ65244.1 - 0.16 10.8 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative Na+/H+ antiporter SR-25 PF10500.9 CDJ65245.1 - 0.012 15.3 27.2 0.012 15.3 27.2 5.1 2 2 2 4 4 4 0 Nuclear RNA-splicing-associated protein Cyt_bd_oxida_II PF02322.15 CDJ65245.1 - 0.69 9.2 4.4 6.7 6.0 2.9 2.1 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II GHMP_kinases_N PF00288.26 CDJ65246.1 - 0.0034 17.6 0.6 0.0034 17.6 0.6 2.7 3 0 0 3 3 3 1 GHMP kinases N terminal domain EOS1 PF12326.8 CDJ65246.1 - 1.2 9.0 6.6 8.4 6.3 0.8 2.3 2 0 0 2 2 2 0 N-glycosylation protein RskA PF10099.9 CDJ65246.1 - 3.6 7.9 42.9 0.055 13.8 14.0 2.7 2 1 0 2 2 2 0 Anti-sigma-K factor rskA LMBR1 PF04791.16 CDJ65246.1 - 4.6 6.0 6.9 7.4 5.3 6.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein mRNA_cap_enzyme PF01331.19 CDJ65247.1 - 7.6e-37 127.0 0.0 2.9e-35 121.9 0.0 2.5 1 1 1 2 2 2 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 CDJ65247.1 - 0.00021 21.0 0.6 0.017 14.7 0.1 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Cpn60_TCP1 PF00118.24 CDJ65249.1 - 1.2e-42 146.2 0.8 1.4e-42 146.0 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3883 PF13020.6 CDJ65250.1 - 5.5e-07 29.5 0.0 8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) BT1 PF03092.16 CDJ65251.1 - 6.4e-75 252.4 13.8 7.6e-51 172.9 11.1 2.1 2 0 0 2 2 2 2 BT1 family tRNA-synt_2c PF01411.19 CDJ65254.1 - 2.4e-198 660.1 0.0 3e-198 659.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CDJ65254.1 - 4.1e-14 52.4 0.1 9.5e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CDJ65254.1 - 3.5e-06 27.5 1.2 1e-05 26.0 1.2 1.8 1 0 0 1 1 1 1 DHHA1 domain RRM_1 PF00076.22 CDJ65255.1 - 1.4e-27 95.3 0.1 6.7e-16 57.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ65255.1 - 2.4e-06 27.6 0.2 0.0016 18.5 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ65255.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Adeno_E3_CR2 PF02439.15 CDJ65259.1 - 0.18 11.6 0.4 0.31 10.8 0.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RAG1 PF12940.7 CDJ65259.1 - 0.21 9.6 0.1 0.31 9.1 0.1 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase Radical_SAM PF04055.21 CDJ65260.1 - 1e-17 65.0 0.0 3.5e-17 63.3 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Radical_SAM_C PF16199.5 CDJ65260.1 - 1.5e-17 63.4 0.0 3e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Acetyltransf_10 PF13673.7 CDJ65260.1 - 0.065 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ65260.1 - 0.066 13.4 0.1 0.21 11.8 0.1 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Glyco_transf_9 PF01075.17 CDJ65260.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) UCH PF00443.29 CDJ65261.1 - 2.5e-14 53.4 0.0 2.3e-13 50.2 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase tRNA-synt_2 PF00152.20 CDJ65262.1 - 2.8e-78 263.2 0.0 3.6e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ65262.1 - 9.1e-11 41.6 0.0 1.8e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDJ65262.1 - 2.3e-07 30.6 0.0 8.8e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SUIM_assoc PF16619.5 CDJ65265.1 - 0.0023 18.0 4.0 0.0023 18.0 4.0 2.4 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 CDJ65265.1 - 1.2 10.1 5.4 26 5.9 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ65265.1 - 7.2 6.1 14.5 1.6 8.3 8.8 2.2 2 0 0 2 2 2 0 Spt20 family RskA PF10099.9 CDJ65266.1 - 0.01 16.2 8.8 0.01 16.2 8.8 5.8 1 1 3 4 4 4 1 Anti-sigma-K factor rskA ETRAMP PF09716.10 CDJ65266.1 - 0.014 15.4 0.4 0.014 15.4 0.4 3.9 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) SUIM_assoc PF16619.5 CDJ65266.1 - 0.2 11.8 7.7 0.54 10.4 7.7 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 CDJ65267.1 - 0.012 15.6 11.8 0.012 15.6 11.8 3.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ65267.1 - 0.43 10.5 33.4 0.8 9.6 33.5 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ65267.1 - 1.1 9.5 36.4 3.9 7.7 9.1 2.5 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Suf PF05843.14 CDJ65267.1 - 2.1 8.2 14.9 0.099 12.6 9.2 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3464 PF11947.8 CDJ65267.1 - 6.9 6.4 8.9 15 5.3 8.9 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Chromo PF00385.24 CDJ65268.1 - 3.6e-07 30.0 0.0 7.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SR-25 PF10500.9 CDJ65271.1 - 0.0025 17.5 33.1 0.0065 16.1 19.2 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein TAF4 PF05236.14 CDJ65271.1 - 0.0026 17.6 8.6 0.0035 17.2 8.6 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TFIIA PF03153.13 CDJ65271.1 - 0.015 15.3 11.5 0.019 15.0 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ65271.1 - 0.086 12.8 12.5 0.11 12.3 12.5 1.0 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ65271.1 - 0.14 10.9 11.4 0.2 10.5 11.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BAF1_ABF1 PF04684.13 CDJ65271.1 - 0.31 10.1 6.6 0.39 9.7 6.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ANAPC_CDC26 PF10471.9 CDJ65271.1 - 0.6 11.0 17.3 0.5 11.2 12.6 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CDJ65271.1 - 1 8.9 15.9 0.51 9.9 13.2 1.7 2 0 0 2 2 2 0 Spt20 family Pap_E4 PF02711.14 CDJ65271.1 - 1.1 10.3 10.4 1.8 9.6 2.1 2.4 2 1 0 2 2 2 0 E4 protein Roughex PF06020.11 CDJ65271.1 - 1.2 8.2 6.5 1.5 7.8 6.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF1635 PF07795.11 CDJ65271.1 - 2.2 8.1 18.3 0.17 11.8 4.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) GREB1 PF15782.5 CDJ65271.1 - 3.1 4.8 16.9 3.9 4.5 16.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4366 PF14283.6 CDJ65271.1 - 3.2 7.8 4.7 34 4.5 5.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Serglycin PF04360.12 CDJ65271.1 - 4 7.4 13.5 0.66 9.9 1.0 2.1 2 0 0 2 2 2 0 Serglycin CDK2AP PF09806.9 CDJ65271.1 - 4.3 7.3 25.7 0.14 12.2 13.5 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Bul1_C PF04426.12 CDJ65271.1 - 5.1 6.4 9.9 0.56 9.6 1.0 2.0 2 0 0 2 2 2 0 Bul1 C terminus TFIIA PF03153.13 CDJ65272.1 - 0.93 9.4 23.3 1.2 9.0 23.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Helicase_C PF00271.31 CDJ65273.1 - 6.2e-18 65.2 0.1 3.5e-17 62.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SpoIIIAH PF12685.7 CDJ65273.1 - 0.0034 17.2 2.9 0.0034 17.2 2.9 3.3 3 1 0 3 3 3 2 SpoIIIAH-like protein SR-25 PF10500.9 CDJ65273.1 - 0.47 10.0 30.4 0.16 11.6 10.7 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ65273.1 - 1 8.1 24.2 1.1 8.0 8.1 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain UPF0565 PF10561.9 CDJ65273.1 - 1.7 7.7 11.1 1.5 7.9 2.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 SLC12 PF03522.15 CDJ65273.1 - 3.3 6.6 35.3 0.19 10.7 6.7 3.1 3 0 0 3 3 3 0 Solute carrier family 12 Pkinase PF00069.25 CDJ65274.1 - 1.3e-48 165.7 0.0 2e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65274.1 - 1.5e-47 162.1 0.0 5.8e-47 160.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ65274.1 - 0.00017 21.0 0.0 0.00039 19.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ65274.1 - 0.00019 20.3 0.0 0.00032 19.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ65274.1 - 0.0043 16.4 0.0 0.008 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ65274.1 - 0.0052 16.7 1.5 0.0052 16.7 1.5 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Transglut_core3 PF13471.6 CDJ65274.1 - 0.0062 16.4 3.5 0.0076 16.2 1.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily SUIM_assoc PF16619.5 CDJ65274.1 - 0.0072 16.4 0.7 0.0072 16.4 0.7 2.2 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ65274.1 - 0.012 14.6 1.1 2.6 6.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF3721 PF12518.8 CDJ65274.1 - 0.17 11.8 1.8 0.4 10.6 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function RskA PF10099.9 CDJ65274.1 - 1 9.7 11.3 5.5 7.3 4.6 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ65274.1 - 2.3 8.1 8.9 4 7.3 0.4 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit M_domain PF12938.7 CDJ65274.1 - 2.5 7.8 21.9 1 9.1 6.3 2.3 2 0 0 2 2 2 0 M domain of GW182 Med15 PF09606.10 CDJ65274.1 - 4.5 5.8 12.2 0.73 8.4 0.5 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Med3 PF11593.8 CDJ65274.1 - 5.6 6.0 21.4 1.5 7.9 7.5 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal SUIM_assoc PF16619.5 CDJ65277.1 - 0.00037 20.5 3.1 0.00037 20.5 3.1 4.0 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 DUF3449 PF11931.8 CDJ65278.1 - 1.2e-64 217.5 13.2 3.3e-53 180.2 0.7 3.3 2 1 1 3 3 3 3 Domain of unknown function (DUF3449) TRAF_BIRC3_bd PF16673.5 CDJ65278.1 - 0.0012 18.6 2.4 1.4 8.8 0.2 2.8 2 0 0 2 2 2 2 TNF receptor-associated factor BIRC3 binding domain Desulfoferrod_N PF06397.12 CDJ65278.1 - 0.081 12.6 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain ADIP PF11559.8 CDJ65278.1 - 0.2 11.7 24.2 1.3 9.1 7.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Ago_PAZ PF18309.1 CDJ65278.1 - 0.3 11.8 4.2 14 6.4 0.3 2.4 2 0 0 2 2 2 0 Argonaute PAZ domain ESX-1_EspG PF14011.6 CDJ65278.1 - 0.32 10.6 3.9 4.1 7.0 2.1 2.1 1 1 1 2 2 2 0 EspG family SAPS PF04499.15 CDJ65278.1 - 0.4 9.4 6.6 0.53 9.0 6.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein INO80_Ies4 PF08193.11 CDJ65278.1 - 1 9.3 10.0 1.4 8.8 2.2 2.1 2 0 0 2 2 2 0 INO80 complex subunit Ies4 Phage_portal PF04860.12 CDJ65278.1 - 1.9 7.6 8.1 4.2 6.5 1.2 2.1 1 1 1 2 2 2 0 Phage portal protein CAF1 PF04857.20 CDJ65278.1 - 3.6 6.7 14.8 1.8e+02 1.1 14.8 2.1 1 1 0 1 1 1 0 CAF1 family ribonuclease Tsg PF04668.12 CDJ65278.1 - 9.4 6.9 6.8 22 5.7 0.6 2.3 1 1 1 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region MFAP1 PF06991.11 CDJ65278.1 - 9.6 6.0 29.4 17 5.2 13.8 2.2 1 1 1 2 2 2 0 Microfibril-associated/Pre-mRNA processing FATC PF02260.20 CDJ65279.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 FATC domain SPX PF03105.19 CDJ65280.1 - 0.0042 17.0 5.1 0.0042 17.0 5.1 2.9 2 1 0 2 2 2 1 SPX domain DUF4366 PF14283.6 CDJ65280.1 - 4.1 7.4 10.5 6.9 6.7 0.1 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4366) SUIM_assoc PF16619.5 CDJ65281.1 - 6.1 7.0 41.8 0.56 10.3 6.2 3.6 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 BT1 PF03092.16 CDJ65282.1 - 9e-06 24.2 6.9 0.00098 17.5 0.1 2.7 3 0 0 3 3 3 2 BT1 family DUF3562 PF12085.8 CDJ65282.1 - 0.073 12.7 0.2 0.63 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) Peptidase_M24_C PF16188.5 CDJ65282.1 - 0.23 11.6 1.3 29 4.8 0.0 3.6 3 0 0 3 3 3 0 C-terminal region of peptidase_M24 MFS_2 PF13347.6 CDJ65282.1 - 0.37 9.3 6.2 0.11 11.1 0.5 2.2 2 0 0 2 2 2 0 MFS/sugar transport protein Prominin PF05478.11 CDJ65282.1 - 1.3 6.9 5.1 1.1 7.1 3.7 1.4 2 0 0 2 2 2 0 Prominin STT3 PF02516.14 CDJ65283.1 - 3.6e-32 112.0 13.4 4.3e-32 111.7 13.4 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit STT3 PF02516.14 CDJ65284.1 - 2.7e-50 171.7 29.7 1.1e-49 169.8 29.7 1.7 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit UXS1_N PF11803.8 CDJ65284.1 - 0.16 12.4 0.4 0.32 11.4 0.4 1.5 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal NolV PF06635.12 CDJ65285.1 - 0.042 13.2 0.8 0.089 12.2 0.8 1.4 1 0 0 1 1 1 0 Nodulation protein NolV F-box PF00646.33 CDJ65286.1 - 0.0016 18.3 0.8 0.056 13.3 0.0 3.3 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.7 CDJ65286.1 - 0.0039 17.0 0.3 0.019 14.8 0.3 2.3 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 CDJ65286.1 - 0.033 15.1 5.4 0.96 10.4 0.2 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat PRTase_2 PF15609.6 CDJ65286.1 - 0.049 13.1 0.2 0.15 11.5 0.2 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase DUF4680 PF15730.5 CDJ65287.1 - 0.0017 18.7 1.7 0.0082 16.5 1.7 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4680) T3SS_LEE_assoc PF13327.6 CDJ65287.1 - 0.29 11.1 3.4 0.29 11.2 0.6 2.5 2 0 0 2 2 2 0 Type III secretion system subunit FUSC_2 PF13515.6 CDJ65288.1 - 9.6e-12 45.1 8.3 9.6e-12 45.1 8.3 3.8 4 1 0 4 4 4 1 Fusaric acid resistance protein-like MMtag PF10159.9 CDJ65289.1 - 1.4e-17 63.7 2.2 1.4e-17 63.7 2.2 4.3 4 1 0 4 4 4 1 Multiple myeloma tumor-associated Cation_ATPase_C PF00689.21 CDJ65290.1 - 4.1e-35 121.1 1.6 4.1e-35 121.1 1.6 3.6 5 1 0 5 5 5 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CDJ65290.1 - 4.3e-35 120.9 4.0 7.8e-35 120.0 0.1 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ65290.1 - 4.2e-17 63.1 0.5 6.2e-10 39.7 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ65290.1 - 4.9e-14 52.2 0.0 9.6e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CDJ65290.1 - 1.1e-07 31.4 0.0 4.4e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDJ65290.1 - 7.7e-05 22.6 0.7 0.0019 18.0 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PAP_central PF04928.17 CDJ65290.1 - 0.12 11.3 0.1 0.26 10.2 0.1 1.5 1 0 0 1 1 1 0 Poly(A) polymerase central domain AMP-binding PF00501.28 CDJ65291.1 - 8.4e-83 278.3 0.1 1.8e-79 267.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ65291.1 - 6.4e-23 81.5 0.5 1.5e-22 80.4 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CDJ65291.1 - 4.7e-16 58.4 1.5 1e-15 57.3 1.5 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus MAS20 PF02064.15 CDJ65292.1 - 0.038 14.1 0.6 0.038 14.1 0.6 1.6 2 0 0 2 2 2 0 MAS20 protein import receptor RNA_pol_3_Rpc31 PF11705.8 CDJ65293.1 - 2.1e-06 28.2 9.1 3e-05 24.4 9.1 2.2 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.10 CDJ65293.1 - 6 7.6 11.1 19 6.0 11.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Ricin_B_lectin PF00652.22 CDJ65294.1 - 0.014 15.6 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain HdeA PF06411.11 CDJ65295.1 - 0.023 14.9 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 HdeA/HdeB family COMP PF11598.8 CDJ65295.1 - 0.095 13.2 0.2 0.19 12.2 0.2 1.4 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein NARP1 PF12569.8 CDJ65297.1 - 6.4e-103 345.4 23.0 3e-78 264.0 13.2 4.0 4 0 0 4 4 4 3 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 CDJ65297.1 - 6.2e-12 44.8 12.8 4.2e-05 23.2 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ65297.1 - 5.1e-08 32.8 12.9 0.025 14.9 0.0 6.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ65297.1 - 2.3e-07 31.3 13.1 0.023 15.3 0.0 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ65297.1 - 8.3e-07 28.7 0.0 3.3e-05 23.7 0.0 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ65297.1 - 2.2e-06 28.0 16.9 0.075 13.9 0.0 8.9 7 3 3 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ65297.1 - 3.3e-06 26.9 20.4 0.0013 18.7 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ65297.1 - 3.8e-05 23.3 4.2 0.15 11.8 0.1 4.1 5 0 0 5 5 5 2 TPR repeat TPR_7 PF13176.6 CDJ65297.1 - 5.3e-05 23.0 9.0 0.094 12.8 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ65297.1 - 0.00015 22.0 13.9 0.39 11.0 0.0 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ65297.1 - 0.00018 21.6 6.1 3.4 7.9 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ65297.1 - 0.00037 20.9 13.8 5.5 7.8 0.0 7.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ65297.1 - 0.0014 19.1 13.5 0.037 14.5 0.1 5.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ65297.1 - 0.062 13.2 1.4 2.2 8.3 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PseudoU_synth_2 PF00849.22 CDJ65298.1 - 4.4e-21 75.6 0.1 2e-20 73.5 0.1 2.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase OTU PF02338.19 CDJ65299.1 - 0.00042 20.8 0.0 0.0022 18.5 0.0 2.0 1 1 0 1 1 1 1 OTU-like cysteine protease PilO PF04350.13 CDJ65299.1 - 0.079 13.1 0.3 0.13 12.4 0.3 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO ABC_tran_Xtn PF12848.7 CDJ65299.1 - 0.18 11.9 1.3 0.5 10.4 1.3 1.8 1 0 0 1 1 1 0 ABC transporter TFIIA PF03153.13 CDJ65299.1 - 1.2 9.0 8.8 1.7 8.6 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BT1 PF03092.16 CDJ65301.1 - 2.8e-68 230.4 26.1 1.9e-40 138.6 14.3 2.1 1 1 1 2 2 2 2 BT1 family MFS_1 PF07690.16 CDJ65301.1 - 3.7e-12 45.9 37.3 9.4e-07 28.1 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CDJ65301.1 - 0.00063 18.7 13.1 0.0012 17.8 13.1 1.4 1 0 0 1 1 1 1 MFS_1 like family Evr1_Alr PF04777.13 CDJ65302.1 - 5.6e-11 42.8 0.1 1.5e-10 41.4 0.1 1.7 2 0 0 2 2 2 1 Erv1 / Alr family Nop52 PF05997.12 CDJ65304.1 - 3e-39 135.1 0.2 4.7e-39 134.4 0.2 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Abhydrolase_3 PF07859.13 CDJ65305.1 - 1.9e-35 122.7 0.0 3.1e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CDJ65305.1 - 4.4e-09 35.8 0.2 1.5e-08 34.0 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 CDJ65305.1 - 1.6e-05 24.0 0.0 2.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 CDJ65305.1 - 0.0016 18.0 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CDJ65305.1 - 0.18 11.6 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chorein_N PF12624.7 CDJ65306.1 - 1.1e-29 102.9 0.7 3.5e-29 101.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CDJ65306.1 - 2.6e-14 53.6 0.0 6.3e-12 45.8 0.0 2.7 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 CDJ65306.1 - 4.4e-06 26.3 0.0 1.5e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 CDJ65306.1 - 3.4e-05 24.1 0.0 0.00021 21.6 0.0 2.4 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 CDJ65306.1 - 0.051 13.3 2.5 18 5.0 0.0 3.4 3 0 0 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal Ist1 PF03398.14 CDJ65307.1 - 2.3e-31 108.9 0.7 3.3e-31 108.4 0.7 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF1586 PF07625.11 CDJ65307.1 - 0.88 9.7 2.7 1.9 8.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) NYN_YacP PF05991.11 CDJ65308.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 YacP-like NYN domain Macoilin PF09726.9 CDJ65311.1 - 0.054 12.1 23.5 0.11 11.1 23.5 1.5 1 0 0 1 1 1 0 Macoilin family Caldesmon PF02029.15 CDJ65311.1 - 0.29 9.8 43.4 0.49 9.1 43.4 1.2 1 0 0 1 1 1 0 Caldesmon GREB1 PF15782.5 CDJ65311.1 - 9.9 3.1 25.1 18 2.2 25.1 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BPL_LplA_LipB PF03099.19 CDJ65312.1 - 1e-09 38.4 0.4 2.1e-09 37.4 0.4 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CDJ65312.1 - 0.00014 21.7 0.0 0.00039 20.3 0.0 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Glyco_hyd_101C PF17451.2 CDJ65312.1 - 0.061 13.6 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain RAP1 PF07218.11 CDJ65313.1 - 1.2 7.4 4.3 1.8 6.7 4.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Vma12 PF11712.8 CDJ65313.1 - 2.7 8.0 7.6 14 5.8 1.9 2.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase LUD_dom PF02589.15 CDJ65314.1 - 0.085 12.6 1.5 1.1 9.0 0.0 3.2 3 1 1 4 4 4 0 LUD domain KIAA1430 PF13879.6 CDJ65314.1 - 0.25 12.1 4.3 0.91 10.3 4.3 2.0 1 0 0 1 1 1 0 KIAA1430 homologue zinc_ribbon_12 PF11331.8 CDJ65316.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon domain Actin PF00022.19 CDJ65320.1 - 2.8e-71 240.3 0.0 2e-70 237.5 0.0 2.1 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CDJ65320.1 - 0.41 9.4 0.7 8.9 5.0 0.0 2.8 3 0 0 3 3 3 0 MreB/Mbl protein Dynamitin PF04912.14 CDJ65321.1 - 5.2e-36 124.8 12.3 9.6e-33 114.1 9.9 2.4 2 1 0 2 2 2 2 Dynamitin DUF4995 PF16386.5 CDJ65321.1 - 0.02 14.9 2.1 5 7.2 0.3 3.7 3 1 0 3 3 3 0 Domain of unknown function NPV_P10 PF05531.12 CDJ65321.1 - 0.47 11.0 2.5 6.3 7.3 0.0 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 CDJ65321.1 - 0.76 9.8 7.8 0.92 9.5 0.2 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Troponin PF00992.20 CDJ65321.1 - 1.1 9.6 7.9 4.7 7.5 1.2 2.9 3 0 0 3 3 3 0 Troponin FlaC_arch PF05377.11 CDJ65321.1 - 2.1 8.8 5.0 14 6.2 0.2 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 CDJ65321.1 - 3 8.3 14.4 8.2 6.9 2.5 3.6 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4094 PF13334.6 CDJ65321.1 - 4.3 7.8 6.5 6.5 7.2 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Exonuc_VII_L PF02601.15 CDJ65321.1 - 9.6 5.7 12.1 11 5.4 5.4 2.7 2 1 0 2 2 2 0 Exonuclease VII, large subunit Muted PF14942.6 CDJ65321.1 - 9.8 6.5 8.4 4.2 7.7 0.5 3.0 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein zf-C3HC4 PF00097.25 CDJ65322.1 - 1.1e-06 28.3 7.9 2.5e-06 27.3 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ65322.1 - 1.1e-05 25.2 7.9 2.7e-05 23.9 7.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ65322.1 - 0.00021 21.4 10.8 0.00046 20.3 10.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CDJ65322.1 - 0.00024 20.9 7.4 0.00047 20.0 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ65322.1 - 0.00037 20.4 8.9 0.00085 19.2 8.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ65322.1 - 0.00042 20.3 6.0 0.001 19.1 6.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 CDJ65322.1 - 0.00049 19.9 4.8 0.0011 18.9 4.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 CDJ65322.1 - 0.0013 19.0 9.5 0.003 17.8 9.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 CDJ65322.1 - 0.019 14.8 2.6 0.043 13.6 2.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Antiterm PF03589.13 CDJ65322.1 - 0.077 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Antitermination protein zf-ANAPC11 PF12861.7 CDJ65322.1 - 0.14 12.3 1.7 0.26 11.4 1.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PagP PF07017.11 CDJ65322.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP Prok-RING_4 PF14447.6 CDJ65322.1 - 0.18 11.7 6.7 0.35 10.8 6.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDJ65322.1 - 1.8 8.4 10.9 5.2 6.9 10.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DNA_pol3_finger PF17657.1 CDJ65326.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit finger domain zf-RING_4 PF14570.6 CDJ65327.1 - 9.9e-20 70.1 10.6 2e-19 69.1 10.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CDJ65327.1 - 7.4e-07 28.9 7.9 1.4e-06 28.0 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CDJ65327.1 - 2.7e-06 27.1 0.0 6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 CDJ65327.1 - 0.0041 17.8 0.1 0.0041 17.8 0.1 2.6 2 0 0 2 2 2 1 Torus domain zf-RING_2 PF13639.6 CDJ65327.1 - 0.01 16.2 11.4 0.01 16.2 11.4 1.9 2 0 0 2 2 2 0 Ring finger domain Baculo_IE-1 PF05290.11 CDJ65327.1 - 0.18 11.8 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 CDJ65327.1 - 0.36 10.7 9.5 12 5.8 9.7 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 CDJ65327.1 - 0.48 10.6 2.8 1.3 9.2 2.8 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 CDJ65327.1 - 7.1 6.9 9.5 24 5.2 9.5 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING TFIIA PF03153.13 CDJ65329.1 - 0.12 12.4 22.1 0.16 11.9 22.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NAP PF00956.18 CDJ65329.1 - 0.48 9.5 11.5 0.77 8.9 11.5 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) V_ATPase_I PF01496.19 CDJ65329.1 - 0.65 7.8 7.8 0.73 7.7 7.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GRIM-19 PF06212.12 CDJ65329.1 - 4.1 7.3 6.8 2.3 8.2 4.2 1.9 1 1 1 2 2 2 0 GRIM-19 protein DUF572 PF04502.13 CDJ65329.1 - 9.9 5.7 11.6 15 5.1 11.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) V-SNARE_C PF12352.8 CDJ65331.1 - 0.0028 17.9 0.3 0.0028 17.9 0.3 3.1 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DUF3433 PF11915.8 CDJ65331.1 - 0.079 13.4 0.3 0.2 12.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) Reeler PF02014.16 CDJ65331.1 - 8.8 7.1 9.1 1.1 10.0 1.1 2.6 2 0 0 2 2 2 0 Reeler domain Pkinase PF00069.25 CDJ65332.1 - 2.3e-17 63.2 0.1 1.3e-15 57.5 0.0 3.3 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65332.1 - 8.7e-09 35.0 0.0 8.7e-09 35.0 0.0 2.7 4 0 0 4 4 4 1 Protein tyrosine kinase Sec16 PF12932.7 CDJ65333.1 - 2.9 8.5 5.0 23 5.6 0.8 2.8 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region SPC12 PF06645.13 CDJ65334.1 - 1.4e-19 69.9 0.8 1.7e-19 69.6 0.8 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Sec62 PF03839.16 CDJ65334.1 - 0.099 12.1 0.2 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Big_5 PF13205.6 CDJ65335.1 - 1.3e-11 45.1 0.0 0.038 14.7 0.0 4.6 4 0 0 4 4 4 4 Bacterial Ig-like domain Notch PF00066.17 CDJ65335.1 - 1.2e-05 25.7 7.4 1.2e-05 25.7 7.4 4.1 3 0 0 3 3 3 1 LNR domain DUF4381 PF14316.6 CDJ65335.1 - 0.022 15.0 0.2 0.022 15.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) CopC PF04234.12 CDJ65335.1 - 0.047 14.7 0.0 4.3 8.5 0.0 3.5 2 1 0 2 2 2 0 CopC domain SIT PF15330.6 CDJ65335.1 - 0.084 13.3 0.0 0.084 13.3 0.0 2.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT SHR3_chaperone PF08229.11 CDJ65335.1 - 2.2 7.2 6.1 0.99 8.3 3.2 1.8 2 0 0 2 2 2 0 ER membrane protein SH3 AP2 PF00847.20 CDJ65336.1 - 2.4e-09 37.3 0.3 2.4e-09 37.3 0.3 3.7 3 0 0 3 3 3 1 AP2 domain ACDC PF14733.6 CDJ65336.1 - 0.17 12.2 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 AP2-coincident C-terminal SPX PF03105.19 CDJ65336.1 - 1.5 8.7 6.2 7.6 6.3 0.1 2.4 2 0 0 2 2 2 0 SPX domain AP2 PF00847.20 CDJ65337.1 - 0.00018 21.7 0.2 0.00018 21.7 0.2 2.8 4 0 0 4 4 4 1 AP2 domain DUF4667 PF15700.5 CDJ65338.1 - 0.0016 18.6 15.9 0.045 13.9 2.7 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ65338.1 - 0.0075 15.9 54.3 0.039 13.6 27.1 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ65338.1 - 0.013 14.4 19.7 0.041 12.8 4.6 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain SpoIIIAH PF12685.7 CDJ65338.1 - 0.42 10.4 12.5 0.38 10.6 1.4 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Macoilin PF09726.9 CDJ65338.1 - 0.55 8.7 21.9 0.15 10.6 5.6 2.0 2 0 0 2 2 2 0 Macoilin family Lin-8 PF03353.15 CDJ65338.1 - 0.68 9.4 12.7 2.3 7.7 2.0 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist LRRFIP PF09738.9 CDJ65338.1 - 0.71 9.3 9.9 2.4 7.5 1.7 2.1 2 0 0 2 2 2 0 LRRFIP family Vitellogenin_N PF01347.22 CDJ65338.1 - 0.87 7.9 5.4 0.25 9.7 0.5 1.9 2 0 0 2 2 2 0 Lipoprotein amino terminal region FAM104 PF15434.6 CDJ65338.1 - 0.89 10.1 26.6 0.54 10.8 8.1 2.5 2 0 0 2 2 2 0 Family 104 Secretin_N_2 PF07655.13 CDJ65338.1 - 1.1 9.8 28.3 0.49 11.0 7.9 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Sec3_C PF09763.9 CDJ65338.1 - 1.3 7.3 6.8 3.3 6.0 1.8 2.0 2 0 0 2 2 2 0 Exocyst complex component Sec3 NPR3 PF03666.13 CDJ65338.1 - 2 7.1 14.2 0.37 9.5 3.0 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Ctr PF04145.15 CDJ65338.1 - 2.7 8.6 4.7 12 6.5 0.3 2.2 2 0 0 2 2 2 0 Ctr copper transporter family NARP1 PF12569.8 CDJ65338.1 - 3.8 6.3 4.0 7.4 5.4 4.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S64 PF08192.11 CDJ65338.1 - 4.8 5.5 15.4 0.46 8.9 2.6 2.0 2 0 0 2 2 2 0 Peptidase family S64 Peroxin-3 PF04882.12 CDJ65338.1 - 4.8 6.1 20.8 4.6 6.1 8.1 2.1 2 0 0 2 2 2 0 Peroxin-3 AF-4 PF05110.13 CDJ65338.1 - 5.4 5.0 46.6 0.084 11.0 14.1 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Mem_trans PF03547.18 CDJ65338.1 - 5.4 5.3 5.2 2 6.7 0.5 2.0 2 0 0 2 2 2 0 Membrane transport protein DUF4050 PF13259.6 CDJ65338.1 - 5.7 7.2 14.5 3.2 8.0 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Rrn6 PF10214.9 CDJ65338.1 - 9.4 4.6 21.4 0.98 7.8 6.7 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Ank_3 PF13606.6 CDJ65341.1 - 7.6e-09 35.1 0.1 0.0062 16.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CDJ65341.1 - 1.8e-08 34.4 0.3 0.007 16.8 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 CDJ65341.1 - 1.1e-07 32.3 0.1 6.9e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ65341.1 - 2.5e-07 31.1 0.1 6e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ65341.1 - 4.4e-06 26.9 1.0 0.0091 16.3 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF4792 PF16040.5 CDJ65342.1 - 0.17 11.8 0.2 0.89 9.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4792) RWD PF05773.22 CDJ65342.1 - 0.18 12.1 0.4 0.57 10.5 0.4 1.7 1 1 0 1 1 1 0 RWD domain F-box PF00646.33 CDJ65343.1 - 0.11 12.4 1.4 0.41 10.6 1.4 2.1 1 0 0 1 1 1 0 F-box domain mRNA_triPase PF02940.15 CDJ65344.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain PP2C PF00481.21 CDJ65345.1 - 7.2e-10 38.9 3.2 3.7e-06 26.8 0.1 3.4 2 2 1 3 3 3 2 Protein phosphatase 2C Selenoprotein_S PF06936.11 CDJ65345.1 - 0.012 15.5 7.3 0.024 14.5 7.3 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) Ribosomal_60s PF00428.19 CDJ65345.1 - 0.018 15.7 11.0 0.018 15.7 11.0 5.9 3 2 1 4 4 1 0 60s Acidic ribosomal protein GREB1 PF15782.5 CDJ65345.1 - 0.35 7.9 11.6 0.42 7.7 11.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ65345.1 - 0.44 10.1 13.6 0.7 9.4 13.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Utp14 PF04615.13 CDJ65345.1 - 0.49 8.9 23.2 0.62 8.6 23.2 1.0 1 0 0 1 1 1 0 Utp14 protein MAP65_ASE1 PF03999.12 CDJ65345.1 - 0.79 8.3 13.2 1.1 7.9 13.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Apt1 PF10351.9 CDJ65345.1 - 0.93 8.3 13.5 1.2 7.9 13.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCSAP PF15748.5 CDJ65345.1 - 1.6 8.9 20.4 2.9 8.0 20.4 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Hid1 PF12722.7 CDJ65345.1 - 2.5 6.1 14.5 3.3 5.7 14.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4667 PF15700.5 CDJ65345.1 - 3.1 7.8 15.4 5.6 7.0 15.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ65345.1 - 3.4 7.5 18.9 6 6.7 18.9 1.4 1 0 0 1 1 1 0 SPX domain DUF572 PF04502.13 CDJ65345.1 - 5.3 6.6 13.6 7.6 6.1 13.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) XRCC4 PF06632.12 CDJ65345.1 - 5.5 5.7 14.2 9.4 5.0 14.2 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SLC12 PF03522.15 CDJ65345.1 - 9.8 5.1 7.2 14 4.5 7.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PPR_2 PF13041.6 CDJ65346.1 - 2.4e-21 75.6 0.0 0.00016 21.8 0.0 6.0 2 1 4 6 6 6 6 PPR repeat family PPR_3 PF13812.6 CDJ65346.1 - 3e-19 68.9 0.0 0.0099 15.9 0.0 5.9 5 1 1 6 6 6 5 Pentatricopeptide repeat domain PPR_long PF17177.4 CDJ65346.1 - 9.3e-19 67.6 18.1 1.7e-08 34.1 0.1 4.9 3 2 3 6 6 6 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CDJ65346.1 - 3.2e-08 33.3 0.0 7.5 7.0 0.0 6.1 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.7 CDJ65346.1 - 6.3e-06 25.8 0.0 12 5.7 0.0 5.6 6 0 0 6 6 6 3 PPR repeat Lebercilin PF15619.6 CDJ65347.1 - 0.00045 19.9 7.3 0.00053 19.7 7.3 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF1151 PF06625.11 CDJ65347.1 - 0.0076 16.2 8.0 0.0096 15.9 8.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) Jnk-SapK_ap_N PF09744.9 CDJ65347.1 - 0.15 12.3 9.4 0.19 12.0 9.4 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Cytadhesin_P30 PF07271.11 CDJ65347.1 - 0.25 10.9 2.6 0.31 10.6 2.6 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Herpes_UL25 PF01499.16 CDJ65347.1 - 0.3 9.5 8.2 0.36 9.3 8.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family CDC73_N PF16050.5 CDJ65347.1 - 1 8.6 7.6 1.2 8.4 7.6 1.0 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal OmpH PF03938.14 CDJ65347.1 - 1.1 9.6 14.6 1.4 9.3 14.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YlqD PF11068.8 CDJ65347.1 - 1.3 9.4 9.3 1.8 8.9 9.3 1.3 1 0 0 1 1 1 0 YlqD protein DUF3138 PF11336.8 CDJ65347.1 - 7.3 5.1 13.0 8.5 4.9 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Presenilin PF01080.17 CDJ65348.1 - 0.0035 16.2 34.7 0.0039 16.0 34.7 1.0 1 0 0 1 1 1 1 Presenilin FAM60A PF15396.6 CDJ65348.1 - 0.0094 16.0 23.3 0.012 15.6 23.3 1.1 1 0 0 1 1 1 1 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ65348.1 - 0.01 15.7 32.8 0.015 15.1 32.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LAP1C PF05609.12 CDJ65348.1 - 0.029 13.5 30.3 0.031 13.4 30.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) WTX PF09422.10 CDJ65348.1 - 0.031 13.4 17.8 0.031 13.4 17.8 1.0 1 0 0 1 1 1 0 WTX protein Plasmodium_Vir PF05795.11 CDJ65348.1 - 0.042 13.3 11.2 0.068 12.6 11.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Raftlin PF15250.6 CDJ65348.1 - 0.35 9.6 25.2 0.4 9.4 25.2 1.0 1 0 0 1 1 1 0 Raftlin MRP-S26 PF14943.6 CDJ65348.1 - 0.51 10.2 28.7 0.7 9.8 28.7 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Pkinase_fungal PF17667.1 CDJ65348.1 - 0.65 8.7 13.7 0.85 8.3 13.7 1.3 1 0 0 1 1 1 0 Fungal protein kinase SLC12 PF03522.15 CDJ65348.1 - 0.65 8.9 34.6 0.77 8.7 34.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Hamartin PF04388.12 CDJ65348.1 - 0.87 8.2 30.7 1 8.0 30.7 1.0 1 0 0 1 1 1 0 Hamartin protein CAC1F_C PF16885.5 CDJ65348.1 - 0.94 9.1 20.1 1.1 8.9 20.1 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term DUF908 PF06012.12 CDJ65348.1 - 1 8.7 23.9 1.7 8.0 23.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) HCO3_cotransp PF00955.21 CDJ65348.1 - 1.2 7.9 13.1 1.5 7.5 13.1 1.2 1 0 0 1 1 1 0 HCO3- transporter family PAT1 PF09770.9 CDJ65348.1 - 1.2 7.3 54.6 1.4 7.1 54.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Membralin PF09746.9 CDJ65348.1 - 1.4 7.8 20.0 1.7 7.6 20.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein Rtf2 PF04641.12 CDJ65348.1 - 1.5 8.1 28.4 2.2 7.6 28.4 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3807 PF12720.7 CDJ65348.1 - 2.2 8.5 42.3 3.9 7.7 42.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF4045 PF13254.6 CDJ65348.1 - 2.6 7.6 32.2 3.1 7.3 32.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Lin-8 PF03353.15 CDJ65348.1 - 2.6 7.5 37.5 3.8 7.0 37.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Dapper PF15268.6 CDJ65348.1 - 3 6.6 38.7 3.5 6.4 38.7 1.0 1 0 0 1 1 1 0 Dapper DUF2052 PF09747.9 CDJ65348.1 - 3.2 7.8 33.3 3.9 7.6 33.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AAA_11 PF13086.6 CDJ65348.1 - 3.2 7.4 34.0 3.9 7.2 34.0 1.1 1 0 0 1 1 1 0 AAA domain SAGA-Tad1 PF12767.7 CDJ65348.1 - 4.4 7.0 28.4 5.4 6.7 28.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1387 PF07139.11 CDJ65348.1 - 5 6.8 33.0 6.9 6.3 33.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Cellulose_synt PF03552.14 CDJ65348.1 - 5.1 5.5 13.0 6.3 5.1 13.0 1.2 1 0 0 1 1 1 0 Cellulose synthase Ndc1_Nup PF09531.10 CDJ65348.1 - 5.4 5.6 34.5 6.3 5.4 34.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Exonuc_VII_L PF02601.15 CDJ65348.1 - 5.5 6.5 35.3 7.2 6.1 35.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CDC45 PF02724.14 CDJ65348.1 - 6.2 5.0 30.6 7.5 4.7 30.6 1.0 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 CDJ65348.1 - 7.2 5.3 27.8 8.7 5.0 27.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 CDJ65348.1 - 8 5.6 23.2 10 5.2 23.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2151 PF10221.9 CDJ65348.1 - 8.2 4.9 22.2 9.2 4.7 22.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator SRP-alpha_N PF04086.13 CDJ65348.1 - 8.3 6.2 30.3 11 5.9 30.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TFIIA PF03153.13 CDJ65349.1 - 0.0056 16.7 16.4 0.0084 16.2 16.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ65349.1 - 0.028 14.0 16.9 0.25 10.9 8.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ65349.1 - 0.69 10.2 29.8 0.025 14.9 14.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF755) FapA PF03961.13 CDJ65349.1 - 4 5.9 7.1 7 5.1 7.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spt20 PF12090.8 CDJ65349.1 - 7.5 6.1 20.5 3.9 7.0 15.4 2.1 2 0 0 2 2 2 0 Spt20 family IHABP4_N PF16174.5 CDJ65350.1 - 7.1 7.2 17.4 8.4 7.0 17.4 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Glyco_transf_7C PF02709.14 CDJ65352.1 - 4.4e-05 23.0 0.0 8.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 CDJ65352.1 - 0.008 15.8 10.5 0.008 15.8 10.5 3.3 3 1 0 3 3 3 1 N-terminal region of glycosyl transferase group 7 DUF4484 PF14831.6 CDJ65352.1 - 6.6 6.7 8.1 18 5.3 8.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) Ras PF00071.22 CDJ65354.1 - 6.1e-44 149.5 0.1 7.1e-44 149.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ65354.1 - 1.3e-32 112.5 0.0 1.6e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ65354.1 - 2e-12 46.9 0.0 2.5e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ65354.1 - 4.2e-08 33.3 0.0 5.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ65354.1 - 1.5e-05 24.6 0.0 0.0011 18.6 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDJ65354.1 - 1.8e-05 24.2 0.0 2.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ65354.1 - 0.0011 18.5 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 CDJ65354.1 - 0.011 15.1 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 0 Septin TniB PF05621.11 CDJ65354.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 CDJ65354.1 - 0.026 14.4 0.1 0.1 12.5 0.1 2.0 1 1 2 3 3 3 0 RsgA GTPase G-alpha PF00503.20 CDJ65354.1 - 0.058 12.5 0.9 0.18 11.0 0.7 1.8 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 CDJ65354.1 - 0.08 12.5 0.2 0.22 11.1 0.1 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 CDJ65354.1 - 0.081 12.6 0.2 0.12 12.1 0.2 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CDJ65354.1 - 0.096 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 CDJ65354.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CDJ65354.1 - 0.12 11.9 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DLIC PF05783.11 CDJ65354.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 CDJ65354.1 - 0.15 12.5 0.0 0.18 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SIR2 PF02146.17 CDJ65355.1 - 1.1e-46 159.0 0.0 1.4e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CDJ65355.1 - 2.6e-05 24.0 0.0 0.0014 18.4 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Med16 PF11635.8 CDJ65355.1 - 0.11 10.4 0.0 0.13 10.1 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 PNTB PF02233.16 CDJ65355.1 - 0.15 10.9 0.1 1 8.2 0.0 1.9 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit GMC_oxred_C PF05199.13 CDJ65357.1 - 4.6e-21 75.9 0.1 4.4e-16 59.7 0.1 2.7 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.19 CDJ65357.1 - 1.9e-09 37.3 0.1 3.1e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Phage_integrase PF00589.22 CDJ65358.1 - 0.064 13.0 0.8 0.12 12.2 0.8 1.3 1 0 0 1 1 1 0 Phage integrase family Ribosomal_L22 PF00237.19 CDJ65359.1 - 5.2e-19 68.4 0.1 7e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ELFV_dehydrog PF00208.21 CDJ65360.1 - 2.7e-78 263.1 0.9 3.5e-78 262.7 0.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CDJ65360.1 - 2.8e-51 172.8 0.0 1.2e-50 170.7 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 CDJ65360.1 - 0.0008 19.8 0.3 0.0019 18.6 0.1 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding ThiF PF00899.21 CDJ65360.1 - 0.02 14.2 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 CDJ65360.1 - 0.035 13.5 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Bac_GDH PF05088.12 CDJ65360.1 - 0.12 9.8 0.2 0.17 9.3 0.2 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase AdoHcyase_NAD PF00670.21 CDJ65360.1 - 0.12 12.4 0.4 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Josephin PF02099.17 CDJ65361.1 - 3.6e-43 147.5 0.0 1.7e-42 145.3 0.0 1.9 2 0 0 2 2 2 1 Josephin UIM PF02809.20 CDJ65361.1 - 0.017 15.0 0.8 0.054 13.4 0.8 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Peptidase_C12 PF01088.21 CDJ65361.1 - 0.17 11.6 0.4 5 6.8 0.0 2.4 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Osmo_CC PF08946.10 CDJ65362.1 - 2.5 8.4 5.6 36 4.7 5.5 2.3 1 1 0 1 1 1 0 Osmosensory transporter coiled coil TFIIA PF03153.13 CDJ65363.1 - 0.4 10.6 17.8 0.47 10.4 17.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ65363.1 - 0.89 8.3 4.3 0.96 8.1 4.3 1.2 1 0 0 1 1 1 0 Presenilin DUF3689 PF12463.8 CDJ65364.1 - 2.3e-31 109.3 13.4 6.3e-12 45.4 0.0 5.2 5 0 0 5 5 5 4 Protein of unknown function (DUF3689) SUIM_assoc PF16619.5 CDJ65364.1 - 0.00055 20.0 0.0 0.00055 20.0 0.0 22.3 17 9 2 19 19 19 5 Unstructured region C-term to UIM in Ataxin3 SPX PF03105.19 CDJ65364.1 - 0.0007 19.6 10.6 0.0007 19.6 10.6 12.7 4 2 0 5 5 5 1 SPX domain ANAPC_CDC26 PF10471.9 CDJ65364.1 - 0.0061 17.4 5.4 0.0061 17.4 5.4 22.2 17 7 3 20 20 20 3 Anaphase-promoting complex APC subunit CDC26 DUF966 PF06136.13 CDJ65364.1 - 0.91 9.2 0.0 0.91 9.2 0.0 12.5 6 5 2 12 12 12 0 Domain of unknown function (DUF966) Glutaredoxin PF00462.24 CDJ65366.1 - 0.13 12.5 1.5 13 6.0 0.0 3.1 3 0 0 3 3 3 0 Glutaredoxin OST3_OST6 PF04756.13 CDJ65366.1 - 0.24 10.7 0.0 0.7 9.2 0.0 1.7 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CDJ65367.1 - 0.2 12.1 0.0 0.43 11.1 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Myosin_head PF00063.21 CDJ65368.1 - 1.6e-27 96.1 0.0 1.4e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) Zeta_toxin PF06414.12 CDJ65368.1 - 0.0074 15.6 0.2 0.085 12.1 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 CDJ65368.1 - 0.023 15.1 0.6 0.33 11.3 0.3 2.5 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CDJ65368.1 - 0.047 14.0 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Myosin_head PF00063.21 CDJ65369.1 - 4e-20 71.6 0.2 6.7e-15 54.4 0.6 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) PGM_PMM_I PF02878.16 CDJ65370.1 - 2.8e-31 108.1 0.1 1.1e-30 106.1 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CDJ65370.1 - 6.5e-24 84.5 0.1 1.8e-23 83.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CDJ65370.1 - 2.3e-13 50.3 0.7 5.4e-13 49.1 0.7 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CDJ65370.1 - 0.026 14.7 1.6 0.068 13.4 0.0 2.6 3 0 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1177 PF06675.11 CDJ65370.1 - 0.15 10.9 0.4 0.33 9.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) RVT_1 PF00078.27 CDJ65372.1 - 8.9e-15 54.8 0.0 3.7e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ65372.1 - 7.1e-09 36.2 0.0 1.6e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ65372.1 - 4.5e-08 33.5 0.0 9.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 CDJ65372.1 - 6.5e-05 22.9 0.3 0.00029 20.8 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 CDJ65372.1 - 0.00027 20.7 0.0 0.00069 19.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 CDJ65372.1 - 0.002 18.1 0.8 0.0035 17.4 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 CDJ65372.1 - 0.026 14.8 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ65372.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease ATG_C PF09333.11 CDJ65374.1 - 0.14 12.6 0.9 3.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain TEA PF01285.18 CDJ65374.1 - 0.21 11.7 0.9 0.84 9.8 0.0 2.3 3 0 0 3 3 3 0 TEA/ATTS domain HSP90 PF00183.18 CDJ65376.1 - 4.9e-115 385.4 4.2 1.5e-68 232.0 0.1 4.4 4 2 0 4 4 4 2 Hsp90 protein HATPase_c_3 PF13589.6 CDJ65376.1 - 7.7e-10 38.7 0.0 1.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ65376.1 - 4.5e-07 30.4 0.1 1e-06 29.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_60s PF00428.19 CDJ65376.1 - 0.0016 19.0 5.4 0.0016 19.0 5.4 7.5 6 1 0 6 6 6 2 60s Acidic ribosomal protein Microtub_bd PF16796.5 CDJ65376.1 - 0.076 12.9 2.3 1.3 9.0 0.5 2.3 2 0 0 2 2 2 0 Microtubule binding Ripply PF14998.6 CDJ65376.1 - 1.6 9.4 10.4 3 8.6 0.2 2.9 2 0 0 2 2 2 0 Transcription Regulator Peptidase_U57 PF05582.12 CDJ65376.1 - 2.6 7.2 8.0 0.28 10.4 2.0 2.2 2 0 0 2 2 2 0 YabG peptidase U57 Peptidase_S28 PF05577.12 CDJ65377.1 - 1.3e-11 44.0 0.0 1.8e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Flg_hook PF02120.16 CDJ65377.1 - 0.34 10.8 0.1 0.34 10.8 0.1 1.9 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Presenilin PF01080.17 CDJ65378.1 - 0.00025 19.9 26.6 0.00027 19.8 26.6 1.0 1 0 0 1 1 1 1 Presenilin DUF3295 PF11702.8 CDJ65378.1 - 0.012 15.0 24.5 0.014 14.8 24.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) LAP1C PF05609.12 CDJ65378.1 - 0.013 14.7 21.5 0.012 14.7 21.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3292 PF11696.8 CDJ65378.1 - 0.015 13.7 16.3 0.018 13.4 16.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) PAT1 PF09770.9 CDJ65378.1 - 0.021 13.2 40.7 0.022 13.0 40.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dsh_C PF12316.8 CDJ65378.1 - 0.021 15.2 10.5 0.025 15.0 10.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal NPR3 PF03666.13 CDJ65378.1 - 0.024 13.4 26.6 0.026 13.3 26.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 CDJ65378.1 - 0.027 12.8 28.0 0.032 12.5 28.0 1.0 1 0 0 1 1 1 0 CDC45-like protein FancD2 PF14631.6 CDJ65378.1 - 0.029 11.8 14.4 0.033 11.6 14.4 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease YABBY PF04690.13 CDJ65378.1 - 0.041 14.5 18.3 0.049 14.2 18.3 1.2 1 0 0 1 1 1 0 YABBY protein Rtf2 PF04641.12 CDJ65378.1 - 0.043 13.2 27.5 0.052 12.9 27.5 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger TRAP_alpha PF03896.16 CDJ65378.1 - 0.044 13.0 8.6 0.067 12.4 8.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CCSAP PF15748.5 CDJ65378.1 - 0.049 13.8 33.3 0.057 13.6 33.3 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ65378.1 - 0.052 13.4 32.4 0.062 13.1 32.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UPF0565 PF10561.9 CDJ65378.1 - 0.057 12.6 9.2 0.064 12.4 9.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 AAA_11 PF13086.6 CDJ65378.1 - 0.06 13.1 26.1 0.068 12.9 26.1 1.0 1 0 0 1 1 1 0 AAA domain Lin-8 PF03353.15 CDJ65378.1 - 0.095 12.2 26.4 0.1 12.1 26.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pannexin_like PF12534.8 CDJ65378.1 - 0.099 11.7 16.9 0.15 11.1 16.9 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 SLC12 PF03522.15 CDJ65378.1 - 0.14 11.2 29.7 0.15 11.0 29.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Velvet PF11754.8 CDJ65378.1 - 0.17 11.8 26.0 0.22 11.4 26.0 1.1 1 0 0 1 1 1 0 Velvet factor DUF5427 PF10310.9 CDJ65378.1 - 0.21 10.5 28.9 0.26 10.2 28.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Ndc1_Nup PF09531.10 CDJ65378.1 - 0.21 10.2 21.6 0.21 10.3 21.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4746 PF15928.5 CDJ65378.1 - 0.21 11.0 19.2 0.29 10.5 19.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GAGA_bind PF06217.12 CDJ65378.1 - 0.22 11.8 23.7 0.27 11.5 23.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Raftlin PF15250.6 CDJ65378.1 - 0.23 10.2 21.0 0.26 10.0 21.0 1.0 1 0 0 1 1 1 0 Raftlin Endostatin PF06482.11 CDJ65378.1 - 0.24 10.8 24.4 0.28 10.6 24.4 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF572 PF04502.13 CDJ65378.1 - 0.29 10.7 27.0 0.36 10.4 27.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF913 PF06025.12 CDJ65378.1 - 0.3 10.0 15.5 0.39 9.7 15.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ureide_permease PF07168.11 CDJ65378.1 - 0.37 9.5 12.0 0.55 8.9 12.0 1.2 1 0 0 1 1 1 0 Ureide permease Apt1 PF10351.9 CDJ65378.1 - 0.4 9.5 19.4 0.44 9.3 19.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase_fungal PF17667.1 CDJ65378.1 - 0.5 9.1 14.1 0.54 9.0 14.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase CENP-N PF05238.13 CDJ65378.1 - 0.52 9.6 18.3 0.63 9.3 18.3 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF3807 PF12720.7 CDJ65378.1 - 0.54 10.5 40.1 0.72 10.1 40.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) PTPRCAP PF15713.5 CDJ65378.1 - 0.64 10.3 27.5 0.99 9.7 27.5 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Cellulose_synt PF03552.14 CDJ65378.1 - 0.66 8.4 10.3 0.71 8.3 10.3 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF2828 PF11443.8 CDJ65378.1 - 0.71 7.9 29.2 0.9 7.5 29.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) BORG_CEP PF14957.6 CDJ65378.1 - 0.78 10.9 19.4 1.1 10.4 19.4 1.2 1 0 0 1 1 1 0 Cdc42 effector Atg14 PF10186.9 CDJ65378.1 - 0.8 8.7 29.5 0.93 8.5 29.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CBP_BcsG PF11658.8 CDJ65378.1 - 0.83 8.0 17.2 1.1 7.5 17.2 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Hid1 PF12722.7 CDJ65378.1 - 0.86 7.6 27.1 1 7.4 27.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CAC1F_C PF16885.5 CDJ65378.1 - 0.97 9.0 17.5 1.1 8.8 17.5 1.0 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term DUF2151 PF10221.9 CDJ65378.1 - 1 7.9 17.8 1.1 7.7 17.8 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator XAP5 PF04921.14 CDJ65378.1 - 1.1 9.1 22.3 1.4 8.7 22.3 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator SAGA-Tad1 PF12767.7 CDJ65378.1 - 1.4 8.6 25.7 1.6 8.4 25.7 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Membralin PF09746.9 CDJ65378.1 - 1.4 7.9 18.7 1.6 7.7 18.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein Neur_chan_memb PF02932.16 CDJ65378.1 - 1.5 8.9 23.7 1.7 8.6 23.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.13 CDJ65378.1 - 1.6 7.6 21.4 1.8 7.4 21.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Gti1_Pac2 PF09729.9 CDJ65378.1 - 1.8 8.6 26.1 2.6 8.1 26.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family XRN_M PF17846.1 CDJ65378.1 - 2.2 7.1 22.7 2.6 6.9 22.7 1.0 1 0 0 1 1 1 0 Xrn1 helical domain AF-4 PF05110.13 CDJ65378.1 - 2.3 6.2 33.7 2.7 6.0 33.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DAG_kinase_N PF14513.6 CDJ65378.1 - 2.4 8.3 27.2 3.2 7.9 27.2 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF2052 PF09747.9 CDJ65378.1 - 2.5 8.2 31.5 3.2 7.8 31.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Vfa1 PF08432.10 CDJ65378.1 - 2.7 8.3 35.1 3.3 8.0 35.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Hamartin PF04388.12 CDJ65378.1 - 2.7 6.6 25.0 3.1 6.4 25.0 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4050 PF13259.6 CDJ65378.1 - 2.8 8.2 24.0 3.9 7.8 24.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) FAM60A PF15396.6 CDJ65378.1 - 2.9 7.8 26.9 3.7 7.5 26.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A LicD PF04991.13 CDJ65378.1 - 3 7.9 16.6 3.6 7.6 16.6 1.1 1 0 0 1 1 1 0 LicD family DDRGK PF09756.9 CDJ65378.1 - 3 7.4 47.3 4.3 6.9 47.3 1.2 1 0 0 1 1 1 0 DDRGK domain VIR_N PF15912.5 CDJ65378.1 - 3.2 7.3 19.5 3.9 7.0 19.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF2370 PF10176.9 CDJ65378.1 - 3.4 7.2 13.2 4.3 6.9 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Paramyxo_ncap PF00973.19 CDJ65378.1 - 3.5 6.4 22.4 3.9 6.3 22.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Band_3_cyto PF07565.13 CDJ65378.1 - 3.5 7.3 26.0 5.8 6.6 26.0 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Smg8_Smg9 PF10220.9 CDJ65378.1 - 4.2 5.6 25.6 4.8 5.4 25.6 1.0 1 0 0 1 1 1 0 Smg8_Smg9 SAPS PF04499.15 CDJ65378.1 - 4.3 6.0 21.8 5 5.8 21.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CLN3 PF02487.17 CDJ65378.1 - 4.4 6.3 24.0 5.4 6.0 24.0 1.1 1 0 0 1 1 1 0 CLN3 protein SID-1_RNA_chan PF13965.6 CDJ65378.1 - 4.6 5.5 14.7 5.2 5.3 14.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hydin_ADK PF17213.3 CDJ65378.1 - 4.8 7.4 22.8 6.8 6.9 22.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MDM10 PF12519.8 CDJ65378.1 - 5 5.9 27.3 6 5.6 27.3 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 HGTP_anticodon2 PF12745.7 CDJ65378.1 - 5.8 6.4 27.0 6.5 6.2 27.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF2126 PF09899.9 CDJ65378.1 - 5.9 4.8 21.0 7.8 4.4 21.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF4569 PF15133.6 CDJ65378.1 - 6.1 6.5 30.5 7.4 6.2 30.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) TCP PF03634.13 CDJ65378.1 - 7 7.2 33.1 9.2 6.8 33.1 1.2 1 0 0 1 1 1 0 TCP family transcription factor MCM_bind PF09739.9 CDJ65378.1 - 7.7 4.8 32.5 9.5 4.5 32.5 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF966 PF06136.13 CDJ65378.1 - 7.8 6.1 22.6 9.2 5.9 22.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) API5 PF05918.11 CDJ65378.1 - 8.2 5.1 30.9 9.1 5.0 30.9 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ALMT PF11744.8 CDJ65378.1 - 8.3 5.1 27.2 10 4.8 27.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CSG2 PF16965.5 CDJ65378.1 - 8.6 5.2 17.3 12 4.8 17.3 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Dicty_REP PF05086.12 CDJ65378.1 - 9.6 4.0 22.7 11 3.9 22.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3446 PF11928.8 CDJ65379.1 - 0.013 15.7 25.1 0.021 15.1 6.1 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain BACK PF07707.15 CDJ65379.1 - 0.016 15.3 0.1 0.062 13.4 0.1 1.9 1 1 0 1 1 1 0 BTB And C-terminal Kelch DUF1645 PF07816.11 CDJ65379.1 - 1.6 9.3 12.3 0.44 11.1 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) PAN_1 PF00024.26 CDJ65380.1 - 4e-17 61.9 22.4 7.1e-07 29.1 2.6 3.3 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 CDJ65380.1 - 6.4e-10 38.8 20.5 5.3e-06 26.2 1.5 4.3 3 1 0 3 3 3 3 PAN domain PAN_2 PF08276.11 CDJ65380.1 - 0.0025 17.9 18.5 0.3 11.2 0.8 3.5 3 0 0 3 3 3 3 PAN-like domain PAN_3 PF08277.12 CDJ65380.1 - 0.028 14.2 0.5 0.028 14.2 0.5 3.3 3 0 0 3 3 3 0 PAN-like domain IMUP PF15761.5 CDJ65380.1 - 2.1 9.1 22.7 3.2 8.5 4.0 3.5 3 0 0 3 3 3 0 Immortalisation up-regulated protein SUIM_assoc PF16619.5 CDJ65380.1 - 7.1 6.8 13.6 0.091 12.8 5.6 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SARAF PF06682.12 CDJ65381.1 - 5.1 6.6 21.4 4.6 6.8 1.4 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Spt20 PF12090.8 CDJ65382.1 - 0.026 14.1 13.0 0.026 14.2 13.0 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ65382.1 - 0.074 12.0 9.9 0.077 11.9 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Ribosomal_60s PF00428.19 CDJ65382.1 - 0.62 10.7 16.8 0.092 13.3 13.2 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ65382.1 - 1.6 8.6 16.6 2 8.3 16.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ASFV_J13L PF05568.11 CDJ65382.1 - 2.2 8.0 8.9 2.9 7.6 8.9 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein BAF1_ABF1 PF04684.13 CDJ65382.1 - 8.8 5.2 6.6 10 5.0 6.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nitroreductase PF00881.24 CDJ65382.1 - 9.3 6.3 9.4 17 5.4 9.4 1.4 1 1 0 1 1 1 0 Nitroreductase family Trypan_PARP PF05887.11 CDJ65383.1 - 0.019 14.9 11.0 0.019 14.9 11.0 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.13 CDJ65384.1 - 0.0021 18.2 39.8 0.0024 18.0 39.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ65384.1 - 0.0091 14.8 16.8 0.0088 14.8 16.8 1.0 1 0 0 1 1 1 1 Presenilin DUF4776 PF16003.5 CDJ65384.1 - 0.12 11.4 18.2 0.14 11.1 18.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Pex14_N PF04695.13 CDJ65384.1 - 0.14 12.8 25.6 0.19 12.4 25.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM60A PF15396.6 CDJ65384.1 - 0.16 11.9 11.1 0.19 11.7 11.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SAGA-Tad1 PF12767.7 CDJ65384.1 - 0.23 11.2 14.4 0.27 11.0 14.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DDHD PF02862.17 CDJ65384.1 - 0.45 10.6 12.4 0.59 10.3 12.4 1.3 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.9 CDJ65384.1 - 0.47 8.6 30.4 0.5 8.6 30.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF5427 PF10310.9 CDJ65384.1 - 0.51 9.2 23.2 0.6 9.0 23.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 CDJ65384.1 - 0.56 9.2 16.7 0.62 9.0 16.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 GNAT_acetyltr_2 PF13718.6 CDJ65384.1 - 0.66 9.3 8.7 0.92 8.9 8.7 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Neur_chan_memb PF02932.16 CDJ65384.1 - 0.67 10.0 14.2 0.79 9.7 14.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.6 CDJ65384.1 - 0.69 9.8 22.1 0.81 9.6 22.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Ribonuc_P_40 PF08584.11 CDJ65384.1 - 0.7 9.1 13.4 0.87 8.8 13.4 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit SpoIIP PF07454.11 CDJ65384.1 - 0.72 9.3 14.9 0.89 9.0 14.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDRGK PF09756.9 CDJ65384.1 - 0.81 9.2 27.9 1 8.9 27.9 1.1 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.12 CDJ65384.1 - 0.89 9.3 17.8 1 9.1 17.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC53 PF10152.9 CDJ65384.1 - 0.93 9.9 17.5 1.4 9.4 17.5 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Serinc PF03348.15 CDJ65384.1 - 0.96 8.3 6.8 1.1 8.1 6.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) eIF-3_zeta PF05091.12 CDJ65384.1 - 0.96 8.4 24.1 1.3 7.9 24.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MAJIN PF15077.6 CDJ65384.1 - 0.99 9.1 12.7 1.2 8.9 12.7 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein SID-1_RNA_chan PF13965.6 CDJ65384.1 - 1 7.7 5.2 0.99 7.7 5.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Exonuc_VII_L PF02601.15 CDJ65384.1 - 1.1 8.8 16.8 1.2 8.6 16.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 CDJ65384.1 - 1.2 8.4 19.3 1.7 7.9 19.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BORG_CEP PF14957.6 CDJ65384.1 - 1.6 9.9 11.3 2.2 9.5 11.3 1.3 1 0 0 1 1 1 0 Cdc42 effector DUF913 PF06025.12 CDJ65384.1 - 1.7 7.5 8.7 2 7.3 8.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 CDJ65384.1 - 2.2 7.0 17.6 2.4 6.8 17.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 LAP1C PF05609.12 CDJ65384.1 - 2.7 7.0 18.7 2.9 6.9 18.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Membralin PF09746.9 CDJ65384.1 - 2.7 6.9 9.8 3.2 6.7 9.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF3616 PF12275.8 CDJ65384.1 - 2.7 7.3 9.7 3.5 7.0 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) NARP1 PF12569.8 CDJ65384.1 - 2.8 6.7 15.6 3.2 6.5 15.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Afi1 PF07792.12 CDJ65384.1 - 3.9 8.0 15.6 5.2 7.5 15.6 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4746 PF15928.5 CDJ65384.1 - 4.2 6.7 13.3 5.2 6.4 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GREB1 PF15782.5 CDJ65384.1 - 4.3 4.3 16.4 4.3 4.3 16.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF3_subunit PF08597.10 CDJ65384.1 - 4.7 7.0 18.1 5.9 6.7 18.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4228 PF14009.6 CDJ65384.1 - 5.9 7.2 12.1 7 7.0 12.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Hydin_ADK PF17213.3 CDJ65384.1 - 8 6.7 13.5 11 6.3 13.5 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CobT PF06213.12 CDJ65384.1 - 8.3 5.7 25.3 11 5.3 25.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Gti1_Pac2 PF09729.9 CDJ65384.1 - 8.4 6.4 15.9 11 6.0 15.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family ALMT PF11744.8 CDJ65384.1 - 8.5 5.1 14.2 10 4.8 14.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Sec62 PF03839.16 CDJ65384.1 - 8.8 5.8 14.7 11 5.4 14.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Hid1 PF12722.7 CDJ65384.1 - 9.6 4.2 18.7 11 4.0 18.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 CDJ65384.1 - 9.9 4.3 19.2 12 4.1 19.2 1.0 1 0 0 1 1 1 0 CDC45-like protein SUIM_assoc PF16619.5 CDJ65385.1 - 0.02 14.9 6.1 0.042 13.9 6.1 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ65385.1 - 0.13 11.8 6.5 0.18 11.4 6.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ65385.1 - 0.15 11.0 1.7 0.19 10.6 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SARAF PF06682.12 CDJ65386.1 - 0.0075 16.0 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Sporozoite_P67 PF05642.11 CDJ65386.1 - 0.019 13.1 4.9 0.03 12.4 4.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF508 PF04370.12 CDJ65386.1 - 0.066 13.0 1.8 0.097 12.4 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) SPX PF03105.19 CDJ65386.1 - 0.11 12.4 0.9 0.12 12.3 0.9 1.1 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 CDJ65386.1 - 0.13 11.9 10.8 0.18 11.4 10.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1645 PF07816.11 CDJ65386.1 - 0.19 12.3 4.5 0.27 11.8 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DUF755 PF05501.11 CDJ65386.1 - 1.8 8.9 13.2 3 8.2 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Secretin_N_2 PF07655.13 CDJ65387.1 - 0.00081 19.9 6.1 0.00081 19.9 6.1 1.9 2 0 0 2 2 2 1 Secretin N-terminal domain DUF4667 PF15700.5 CDJ65387.1 - 0.0089 16.1 1.9 0.0089 16.1 1.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ65387.1 - 1.3 8.9 14.2 0.048 13.6 2.0 2.1 2 0 0 2 2 2 0 SPX domain Tmemb_cc2 PF10267.9 CDJ65387.1 - 1.4 8.0 15.3 3.4 6.7 7.0 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF1635 PF07795.11 CDJ65387.1 - 1.5 8.6 13.1 0.29 11.0 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) YebO PF13974.6 CDJ65387.1 - 1.8 8.7 12.1 0.14 12.2 5.3 2.6 3 0 0 3 3 3 0 YebO-like protein TFIIA PF03153.13 CDJ65387.1 - 5.7 6.8 24.6 3.5 7.5 19.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ65388.1 - 0.022 14.8 0.9 0.022 14.8 0.9 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Toxin_ToxA PF11584.8 CDJ65388.1 - 0.025 14.6 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA Ribosomal_60s PF00428.19 CDJ65388.1 - 0.19 12.3 6.2 0.49 11.0 6.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein HEPN_SAV_6107 PF18726.1 CDJ65388.1 - 0.19 12.2 4.8 0.57 10.7 4.8 1.8 1 0 0 1 1 1 0 SAV_6107-like HEPN Meth_synt_1 PF08267.12 CDJ65389.1 - 0.73 9.3 3.0 0.99 8.8 3.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain SUIM_assoc PF16619.5 CDJ65389.1 - 8.5 6.5 14.2 21 5.2 14.2 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Avian_gp85 PF03708.14 CDJ65390.1 - 0.091 11.9 1.2 0.15 11.2 1.2 1.3 1 0 0 1 1 1 0 Avian retrovirus envelope protein, gp85 CPBP PF02517.16 CDJ65391.1 - 8.2e-09 35.7 16.3 1e-05 25.8 16.3 4.9 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease Neur_chan_memb PF02932.16 CDJ65391.1 - 0.22 11.6 3.0 14 5.6 0.1 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 CDJ65391.1 - 0.44 9.4 16.8 4.6 6.1 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2722) DUF2973 PF11189.8 CDJ65391.1 - 3.4 7.8 6.6 0.51 10.5 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) DUF5080 PF16883.5 CDJ65392.1 - 0.013 15.7 0.1 0.019 15.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5080) CopD PF05425.13 CDJ65392.1 - 0.038 14.4 3.1 0.077 13.4 0.0 2.8 2 1 1 3 3 3 0 Copper resistance protein D zf-CpG_bind_C PF12269.8 CDJ65393.1 - 0.056 13.2 23.0 0.085 12.6 23.0 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Pro_racemase PF05544.11 CDJ65393.1 - 1.8 7.5 5.8 2.1 7.3 5.8 1.2 1 0 0 1 1 1 0 Proline racemase SR-25 PF10500.9 CDJ65394.1 - 0.0051 16.5 11.6 0.0051 16.5 11.6 4.4 3 1 1 4 4 4 3 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ65395.1 - 0.012 15.6 0.3 0.012 15.6 0.3 8.9 6 5 2 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 FAST_1 PF06743.15 CDJ65395.1 - 0.079 12.9 1.4 0.19 11.7 1.4 1.6 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 Nha1_C PF08619.10 CDJ65396.1 - 0.057 12.6 0.0 0.057 12.6 0.0 8.7 7 2 1 9 9 9 0 Alkali metal cation/H+ antiporter Nha1 C terminus PH PF00169.29 CDJ65396.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 PH domain EF-hand_1 PF00036.32 CDJ65397.1 - 4.7e-05 22.6 0.0 0.076 12.6 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ65397.1 - 0.00028 20.6 0.0 0.37 10.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CDJ65397.1 - 0.0034 17.8 0.0 2.4 8.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ65397.1 - 0.015 15.2 0.0 3 7.8 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 CDJ65397.1 - 0.015 14.8 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 EF hand DUF4834 PF16118.5 CDJ65397.1 - 0.031 15.2 7.7 8.2 7.5 0.7 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ65397.1 - 1.5 7.6 32.7 0.042 12.8 4.3 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ65397.1 - 7.8 6.6 51.9 2.2 8.4 13.9 4.9 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Glyco_hydro_19 PF00182.19 CDJ65398.1 - 6.7e-08 32.7 0.0 3.4e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Chitinase class I PUL PF08324.11 CDJ65399.1 - 3.1e-30 105.4 5.8 3.1e-30 105.4 5.8 1.9 2 0 0 2 2 2 1 PUL domain PFU PF09070.11 CDJ65399.1 - 1.1e-23 83.7 0.0 3.3e-23 82.1 0.0 1.9 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CDJ65399.1 - 1.7e-09 38.1 11.2 0.008 17.0 0.0 6.2 5 1 0 5 5 5 2 WD domain, G-beta repeat DUF2722 PF10846.8 CDJ65399.1 - 2.1e-05 23.7 2.7 2.1e-05 23.7 2.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ65399.1 - 4.8e-05 23.7 28.5 4.8e-05 23.7 28.5 4.3 4 2 1 5 5 5 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ65399.1 - 0.0026 17.8 18.4 0.0026 17.8 18.4 3.5 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ65399.1 - 0.011 15.7 4.9 0.011 15.7 4.9 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ65399.1 - 0.017 14.7 30.4 0.1 12.2 18.8 2.7 2 0 0 2 2 2 0 Spt20 family DUF4820 PF16091.5 CDJ65399.1 - 0.044 13.2 7.7 0.12 11.8 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DDHD PF02862.17 CDJ65399.1 - 0.097 12.8 4.8 0.47 10.6 1.4 2.7 2 0 0 2 2 2 0 DDHD domain EBP50_C PF09007.11 CDJ65399.1 - 0.16 12.9 0.2 0.16 12.9 0.2 3.4 3 0 0 3 3 3 0 EBP50, C-terminal RAB3GAP2_N PF14655.6 CDJ65399.1 - 0.41 9.9 11.6 0.75 9.0 5.4 2.7 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4179 PF13786.6 CDJ65399.1 - 0.98 9.9 3.5 5.8 7.4 1.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) EphA2_TM PF14575.6 CDJ65399.1 - 1.2 10.0 5.8 7.1 7.6 0.5 3.1 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4770 PF15994.5 CDJ65399.1 - 1.2 9.3 6.0 21 5.3 4.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF533 PF04391.12 CDJ65399.1 - 1.6 8.2 20.6 25 4.4 17.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF533) FHIPEP PF00771.20 CDJ65399.1 - 1.7 7.1 6.9 0.62 8.5 2.6 2.3 3 0 0 3 3 3 0 FHIPEP family PAT1 PF09770.9 CDJ65399.1 - 1.8 6.8 14.9 0.19 10.0 7.4 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ65399.1 - 2.4 7.7 16.6 0.69 9.5 2.5 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF5327 PF17261.2 CDJ65399.1 - 2.8 8.8 15.7 28 5.5 9.8 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Slu7 PF11708.8 CDJ65399.1 - 3.3 7.4 12.6 7 6.3 0.0 3.0 3 0 0 3 3 3 0 Pre-mRNA splicing Prp18-interacting factor DUF2613 PF11021.8 CDJ65399.1 - 3.4 7.8 12.8 13 6.0 5.8 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF3357 PF11837.8 CDJ65399.1 - 3.7 8.0 8.2 4.4 7.8 5.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Dehydrin PF00257.19 CDJ65399.1 - 4 8.0 14.7 3.8 8.0 2.3 3.3 3 0 0 3 3 3 0 Dehydrin Pex14_N PF04695.13 CDJ65399.1 - 4.3 8.0 29.1 0.81 10.3 11.5 3.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ65400.1 - 0.0018 18.3 30.8 0.0018 18.3 30.8 5.8 2 1 2 4 4 4 1 Transcription factor IIA, alpha/beta subunit JAB PF01398.21 CDJ65401.1 - 0.025 14.5 0.8 0.28 11.2 0.0 2.8 3 0 0 3 3 3 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4315 PF14193.6 CDJ65403.1 - 0.059 13.4 2.9 0.17 11.9 2.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) SHE3 PF17078.5 CDJ65403.1 - 0.067 12.9 1.1 0.14 11.8 1.1 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF1664 PF07889.12 CDJ65403.1 - 0.099 12.7 0.7 0.23 11.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4094 PF13334.6 CDJ65403.1 - 0.95 9.9 5.8 0.31 11.5 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Mto2_bdg PF12808.7 CDJ65403.1 - 1 9.7 4.4 1.1 9.6 1.8 2.2 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF5542 PF17696.1 CDJ65403.1 - 1.4 9.1 4.4 3.1 8.0 0.1 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5542) KELK PF15796.5 CDJ65403.1 - 5 7.6 8.2 5.3 7.6 3.9 2.5 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2968 PF11180.8 CDJ65403.1 - 8.6 6.0 13.9 0.057 13.1 4.8 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) UCR_UQCRX_QCR9 PF05365.12 CDJ65404.1 - 0.073 13.0 2.7 0.28 11.1 1.1 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Collagen PF01391.18 CDJ65405.1 - 0.00017 21.3 44.0 0.00017 21.3 44.0 3.7 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Med15 PF09606.10 CDJ65407.1 - 0.0078 15.0 36.0 0.0082 14.9 36.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 CDJ65407.1 - 2.1 7.0 20.4 2.5 6.8 20.4 1.1 1 0 0 1 1 1 0 Presenilin XRN_M PF17846.1 CDJ65407.1 - 4 6.3 10.6 4.8 6.0 10.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF4551 PF15087.6 CDJ65407.1 - 4.4 6.0 16.7 5 5.8 16.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Raftlin PF15250.6 CDJ65407.1 - 4.8 5.8 13.2 5.6 5.6 13.2 1.1 1 0 0 1 1 1 0 Raftlin Utp14 PF04615.13 CDJ65408.1 - 5e-32 111.4 0.3 6e-32 111.1 0.3 1.0 1 0 0 1 1 1 1 Utp14 protein RepA1_leader PF08048.12 CDJ65408.1 - 0.16 12.3 4.3 0.36 11.2 4.3 1.6 1 0 0 1 1 1 0 Tap RepA1 leader peptide OAD_gamma PF04277.13 CDJ65408.1 - 0.42 11.2 5.4 0.61 10.7 4.7 1.7 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Fip1 PF05182.13 CDJ65409.1 - 0.00036 20.0 0.2 0.00097 18.6 0.2 1.8 1 0 0 1 1 1 1 Fip1 motif Presenilin PF01080.17 CDJ65409.1 - 5.1 5.8 21.7 9.4 4.9 21.7 1.5 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ65409.1 - 8.6 6.3 23.0 1.9 8.5 19.6 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Shadoo PF14999.6 CDJ65410.1 - 0.0031 17.6 5.1 0.0048 17.0 5.1 1.4 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective DUF1104 PF06518.11 CDJ65410.1 - 0.0039 17.5 2.2 0.006 16.9 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1104) DUF4179 PF13786.6 CDJ65410.1 - 0.015 15.8 1.2 0.021 15.3 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Spem1 PF15670.5 CDJ65410.1 - 0.019 14.6 8.6 0.022 14.4 8.6 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF2232 PF09991.9 CDJ65410.1 - 0.035 13.3 0.9 0.042 13.0 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) FHIPEP PF00771.20 CDJ65410.1 - 0.083 11.4 3.2 0.093 11.2 3.2 1.0 1 0 0 1 1 1 0 FHIPEP family TMEM247 PF15444.6 CDJ65410.1 - 0.085 12.9 7.2 0.11 12.5 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 Med3 PF11593.8 CDJ65410.1 - 0.17 11.0 31.0 0.17 11.0 31.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ65410.1 - 0.18 12.1 28.8 0.55 10.5 28.8 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ65410.1 - 0.23 11.4 31.8 0.23 11.4 31.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NEMP PF10225.9 CDJ65410.1 - 0.23 11.1 2.4 0.25 11.0 2.4 1.1 1 0 0 1 1 1 0 NEMP family Oleosin PF01277.17 CDJ65410.1 - 0.38 10.5 3.1 0.51 10.1 3.1 1.1 1 0 0 1 1 1 0 Oleosin Roughex PF06020.11 CDJ65410.1 - 0.39 9.8 10.8 0.38 9.8 10.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein eIF-3_zeta PF05091.12 CDJ65410.1 - 0.43 9.5 11.9 0.45 9.4 11.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 CDJ65410.1 - 0.48 9.7 14.1 0.57 9.5 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM199X PF15814.5 CDJ65410.1 - 0.52 9.3 6.7 0.64 9.0 6.7 1.1 1 0 0 1 1 1 0 Protein family FAM199X RPA43_OB PF17875.1 CDJ65410.1 - 0.67 10.6 10.2 0.92 10.1 10.2 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Ctr PF04145.15 CDJ65410.1 - 0.67 10.6 4.4 0.77 10.4 4.4 1.2 1 0 0 1 1 1 0 Ctr copper transporter family MMR1 PF08505.10 CDJ65410.1 - 0.73 10.1 11.7 0.75 10.0 11.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Suf PF05843.14 CDJ65410.1 - 0.73 9.8 11.8 0.77 9.7 11.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_UL32 PF06070.11 CDJ65410.1 - 0.99 7.1 12.7 1.1 7.0 12.7 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Connexin PF00029.19 CDJ65410.1 - 1.1 9.0 5.2 1.2 8.8 5.2 1.1 1 0 0 1 1 1 0 Connexin Ribosomal_60s PF00428.19 CDJ65410.1 - 1.1 9.8 19.9 0.36 11.5 16.5 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Serinc PF03348.15 CDJ65410.1 - 1.9 7.3 3.7 1.9 7.3 3.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spt20 PF12090.8 CDJ65410.1 - 2 8.0 32.0 2.4 7.7 32.0 1.1 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ65410.1 - 2.2 9.3 10.6 3.3 8.7 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TERB2 PF15101.6 CDJ65410.1 - 2.2 8.3 15.6 2.7 8.0 15.6 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 R_equi_Vir PF05526.11 CDJ65410.1 - 3.5 7.5 9.7 4.8 7.0 9.7 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein CLN3 PF02487.17 CDJ65410.1 - 5.4 5.9 5.7 5.7 5.9 5.7 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4342 PF14242.6 CDJ65410.1 - 6.7 6.8 5.7 11 6.0 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Hid1 PF12722.7 CDJ65410.1 - 7.5 4.5 9.3 7.2 4.6 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 CDJ65410.1 - 8.9 6.3 9.7 8.7 6.3 9.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 CDJ65410.1 - 9.1 5.1 28.1 1.4 7.7 24.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) PLAC8 PF04749.17 CDJ65412.1 - 0.018 16.1 11.6 0.039 14.9 11.6 1.6 1 0 0 1 1 1 0 PLAC8 family DUF2207 PF09972.9 CDJ65412.1 - 0.89 8.2 2.7 3.2 6.4 2.0 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RskA PF10099.9 CDJ65412.1 - 1.1 9.5 8.2 31 4.8 8.2 2.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ65413.1 - 0.00013 21.4 0.1 0.00013 21.4 0.1 11.5 6 3 0 7 7 7 1 Sin-like protein conserved region BUD22 PF09073.10 CDJ65413.1 - 0.0013 18.2 16.3 0.0013 18.2 16.3 8.8 7 3 1 8 8 8 2 BUD22 MFS_5 PF05631.14 CDJ65413.1 - 0.023 13.6 0.7 0.055 12.4 0.7 1.5 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM GRASP55_65 PF04495.14 CDJ65414.1 - 5.4e-08 33.3 0.0 9.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain RAB3GAP2_N PF14655.6 CDJ65415.1 - 0.0019 17.6 1.7 0.0019 17.6 1.7 4.6 5 0 0 5 5 5 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Tic110 PF16940.5 CDJ65415.1 - 0.0031 16.1 0.3 0.0031 16.1 0.3 4.5 4 0 0 4 4 4 1 Chloroplast envelope transporter MecA PF05389.12 CDJ65415.1 - 0.44 10.1 3.5 6.3 6.4 0.1 2.5 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Ribosomal_L36e PF01158.18 CDJ65417.1 - 1.6e-38 130.8 4.6 1.8e-38 130.6 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Bystin PF05291.11 CDJ65418.1 - 1.9e-112 375.3 2.5 2.8e-112 374.8 2.5 1.2 1 0 0 1 1 1 1 Bystin CcdA PF07362.12 CDJ65418.1 - 0.15 12.5 1.9 8.4 6.9 0.1 2.9 2 1 0 2 2 2 0 Post-segregation antitoxin CcdA rve_3 PF13683.6 CDJ65420.1 - 0.039 13.7 0.1 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 Integrase core domain rve PF00665.26 CDJ65420.1 - 0.048 13.9 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain SR-25 PF10500.9 CDJ65421.1 - 0.0051 16.5 3.8 0.0051 16.5 3.8 5.8 5 1 1 6 6 6 2 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ65423.1 - 0.0069 16.0 85.6 0.037 13.6 21.2 3.9 2 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ65423.1 - 0.044 14.1 57.3 0.74 10.2 16.7 3.7 3 0 0 3 3 3 0 Early growth response N-terminal domain RskA PF10099.9 CDJ65423.1 - 0.053 13.8 37.2 0.27 11.5 6.2 3.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 CDJ65423.1 - 4.1 6.4 37.3 3.9 6.4 19.1 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF533 PF04391.12 CDJ65423.1 - 6 6.4 36.5 0.3 10.7 9.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF533) Shadoo PF14999.6 CDJ65423.1 - 9.4 6.3 18.4 0.2 11.7 11.1 1.9 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective CAP PF00188.26 CDJ65425.1 - 0.014 16.2 0.1 0.019 15.8 0.1 1.3 1 0 0 1 1 1 0 Cysteine-rich secretory protein family WD40 PF00400.32 CDJ65426.1 - 2.8e-14 53.3 19.6 0.00063 20.5 0.4 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat YfcL PF08891.11 CDJ65428.1 - 2.3 8.6 5.6 0.35 11.3 0.8 2.1 2 0 0 2 2 2 0 YfcL protein TMEM131_like PF12371.8 CDJ65429.1 - 1.5e-08 34.7 0.1 7.1e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Transmembrane protein 131-like ASH PF15780.5 CDJ65429.1 - 9.9e-07 28.9 0.0 2e-05 24.7 0.0 2.8 3 0 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CDJ65429.1 - 0.00012 22.1 0.4 0.32 11.2 0.0 3.7 3 1 0 3 3 3 2 Flagellar-associated PapD-like Motile_Sperm PF00635.26 CDJ65429.1 - 0.096 12.5 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 MSP (Major sperm protein) domain DUF4574 PF15141.6 CDJ65431.1 - 0.41 10.6 2.4 2.1 8.3 2.4 2.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Vps26 PF03643.15 CDJ65432.1 - 1.8e-106 355.2 1.3 2e-106 355.0 1.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CDJ65432.1 - 0.0026 17.8 1.3 4.2 7.4 0.0 3.3 2 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain CAP PF00188.26 CDJ65434.1 - 3.6e-11 44.0 0.2 3.6e-11 44.0 0.2 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ELH PF02323.15 CDJ65434.1 - 0.0016 17.9 0.1 0.002 17.5 0.1 1.1 1 0 0 1 1 1 1 Egg-laying hormone precursor PTS_2-RNA PF01885.16 CDJ65435.1 - 7e-17 62.0 0.0 2.9e-16 60.1 0.0 2.0 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family V_ATPase_I PF01496.19 CDJ65435.1 - 8.3 4.2 17.8 2.1 6.2 13.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PCI PF01399.27 CDJ65436.1 - 5.7e-12 46.1 0.6 1e-11 45.3 0.6 1.4 1 0 0 1 1 1 1 PCI domain RPN6_N PF18055.1 CDJ65436.1 - 7e-08 32.8 0.0 2.6e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain RPN6_C_helix PF18503.1 CDJ65436.1 - 0.037 13.8 0.2 0.084 12.6 0.2 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain Serglycin PF04360.12 CDJ65436.1 - 0.79 9.7 2.6 0.72 9.8 0.4 2.0 2 0 0 2 2 2 0 Serglycin TPR_7 PF13176.6 CDJ65436.1 - 2.6 8.3 12.3 5.9 7.2 0.1 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 CDJ65436.1 - 7 6.8 8.2 19 5.4 0.0 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF2722 PF10846.8 CDJ65437.1 - 0.00017 20.7 12.4 0.00017 20.7 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ65437.1 - 0.0025 17.9 14.5 0.0025 17.9 14.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Afaf PF15339.6 CDJ65437.1 - 0.0072 16.1 0.1 0.0089 15.8 0.1 1.1 1 0 0 1 1 1 1 Acrosome formation-associated factor Med15 PF09606.10 CDJ65437.1 - 0.0097 14.7 16.1 0.0098 14.6 16.1 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal EPL1 PF10513.9 CDJ65437.1 - 0.011 16.1 2.5 0.012 16.1 2.5 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Suf PF05843.14 CDJ65437.1 - 0.013 15.5 7.2 0.014 15.4 7.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex26 PF07163.12 CDJ65437.1 - 0.015 14.7 7.0 0.018 14.4 7.0 1.1 1 0 0 1 1 1 0 Pex26 protein Topoisom_I_N PF02919.15 CDJ65437.1 - 0.018 14.5 0.7 0.02 14.4 0.7 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Peroxin-3 PF04882.12 CDJ65437.1 - 0.02 13.9 5.6 0.023 13.7 5.6 1.1 1 0 0 1 1 1 0 Peroxin-3 GvpL_GvpF PF06386.11 CDJ65437.1 - 0.025 14.5 4.2 0.029 14.3 4.2 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF CDC45 PF02724.14 CDJ65437.1 - 0.025 12.9 3.2 0.027 12.8 3.2 1.0 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 CDJ65437.1 - 0.03 14.5 1.9 0.032 14.4 1.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal EIIBC-GUT_N PF03612.14 CDJ65437.1 - 0.034 13.9 3.5 0.043 13.6 3.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4643 PF15485.6 CDJ65437.1 - 0.035 14.0 5.7 0.04 13.7 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) Endonuc_Holl PF10107.9 CDJ65437.1 - 0.037 13.9 2.2 0.046 13.6 2.2 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Presenilin PF01080.17 CDJ65437.1 - 0.044 12.6 1.9 0.041 12.7 1.9 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ65437.1 - 0.084 13.8 5.5 0.12 13.4 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) OATP PF03137.20 CDJ65437.1 - 0.098 10.9 0.9 0.095 11.0 0.9 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4820 PF16091.5 CDJ65437.1 - 0.11 11.8 6.7 0.19 11.1 6.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) Mit_KHE1 PF10173.9 CDJ65437.1 - 0.13 12.4 2.0 0.16 12.1 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related RPA43_OB PF17875.1 CDJ65437.1 - 0.15 12.7 4.4 0.2 12.3 4.4 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Folate_carrier PF01770.18 CDJ65437.1 - 0.15 10.8 2.3 0.18 10.5 2.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier SprA-related PF12118.8 CDJ65437.1 - 0.18 10.9 14.6 0.17 11.0 14.6 1.2 1 0 0 1 1 1 0 SprA-related family UPF0560 PF10577.9 CDJ65437.1 - 0.21 10.1 10.6 0.22 10.0 10.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4407 PF14362.6 CDJ65437.1 - 0.23 10.8 9.2 0.24 10.7 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Roughex PF06020.11 CDJ65437.1 - 0.37 9.9 8.2 0.39 9.7 8.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein TERB2 PF15101.6 CDJ65437.1 - 0.42 10.6 9.9 0.51 10.4 9.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ65437.1 - 0.44 10.1 27.3 0.58 9.7 27.3 1.1 1 0 0 1 1 1 0 Spt20 family CLN3 PF02487.17 CDJ65437.1 - 0.45 9.5 2.4 0.52 9.3 2.4 1.1 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 CDJ65437.1 - 0.47 10.5 3.8 0.55 10.3 3.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.6 CDJ65437.1 - 0.55 8.1 20.0 0.59 8.0 20.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Tht1 PF04163.12 CDJ65437.1 - 0.64 8.7 3.9 0.72 8.5 3.9 1.0 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein USP8_interact PF08941.10 CDJ65437.1 - 0.72 9.7 7.9 0.93 9.3 7.9 1.2 1 0 0 1 1 1 0 USP8 interacting DUF4199 PF13858.6 CDJ65437.1 - 1 9.7 3.0 1.2 9.5 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) RR_TM4-6 PF06459.12 CDJ65437.1 - 2.1 8.1 9.2 2.7 7.7 9.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3464 PF11947.8 CDJ65437.1 - 2.6 7.8 6.3 3.3 7.5 6.3 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DivIC PF04977.15 CDJ65437.1 - 6.3 6.6 18.2 10 5.9 18.2 1.4 1 0 0 1 1 1 0 Septum formation initiator G0-G1_switch_2 PF15103.6 CDJ65437.1 - 7.9 7.0 8.6 10 6.6 8.4 1.4 1 1 0 1 1 1 0 G0/G1 switch protein 2 SKA1 PF07160.12 CDJ65438.1 - 0.25 11.1 15.3 0.36 10.7 15.3 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Draxin PF15550.6 CDJ65438.1 - 0.44 10.4 6.2 0.58 10.0 6.2 1.3 1 0 0 1 1 1 0 Draxin DUF3584 PF12128.8 CDJ65438.1 - 0.72 7.3 21.0 0.88 7.0 21.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PCM1_C PF15717.5 CDJ65438.1 - 0.8 8.3 13.1 1.1 7.9 13.1 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus PAT1 PF09770.9 CDJ65438.1 - 1.5 7.0 23.8 1.5 7.0 23.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 2OG-FeII_Oxy_2 PF13532.6 CDJ65438.1 - 2.1 8.5 7.7 2.3 8.4 6.8 1.5 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily MDM10 PF12519.8 CDJ65438.1 - 2.4 6.9 6.1 2.4 6.9 6.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 ABC2_membrane_2 PF12679.7 CDJ65438.1 - 2.5 7.3 5.3 3 7.1 5.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Lin-8 PF03353.15 CDJ65438.1 - 2.8 7.4 20.2 3.3 7.2 20.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mcm10 PF09332.11 CDJ65438.1 - 3.2 7.1 17.3 4 6.8 17.3 1.1 1 0 0 1 1 1 0 Mcm10 replication factor YABBY PF04690.13 CDJ65438.1 - 4.9 7.7 9.7 7.2 7.1 9.7 1.4 1 0 0 1 1 1 0 YABBY protein V_ATPase_I PF01496.19 CDJ65438.1 - 5.5 4.8 8.9 5.8 4.7 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4048 PF13257.6 CDJ65439.1 - 0.2 11.4 8.7 0.98 9.2 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4048) DUF2722 PF10846.8 CDJ65439.1 - 0.49 9.3 10.4 0.82 8.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ65439.1 - 2.6 8.2 35.4 1.1 9.3 8.6 4.1 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 V-ATPase_H_C PF11698.8 CDJ65440.1 - 2.2e-29 101.9 0.8 1.1e-28 99.6 0.3 2.1 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 CDJ65440.1 - 9.8e-18 64.5 0.0 2e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 V-ATPase subunit H NPR3 PF03666.13 CDJ65440.1 - 0.01 14.6 4.3 0.016 14.0 4.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF966 PF06136.13 CDJ65440.1 - 0.011 15.5 7.5 0.015 15.0 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Ndc1_Nup PF09531.10 CDJ65440.1 - 0.015 14.1 5.7 0.018 13.8 5.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 CDJ65440.1 - 0.029 14.4 30.7 0.037 14.0 30.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ65440.1 - 0.039 14.1 4.1 0.057 13.6 4.1 1.3 1 0 0 1 1 1 0 DDHD domain FAM76 PF16046.5 CDJ65440.1 - 0.04 13.3 9.1 0.068 12.5 9.1 1.3 1 0 0 1 1 1 0 FAM76 protein Cyt-b5 PF00173.28 CDJ65440.1 - 0.056 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain AF-4 PF05110.13 CDJ65440.1 - 0.076 11.1 15.7 0.1 10.7 15.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein eIF-3_zeta PF05091.12 CDJ65440.1 - 0.1 11.6 12.5 0.14 11.1 12.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 CDJ65440.1 - 0.15 12.1 10.6 0.28 11.2 10.6 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ65440.1 - 0.15 10.8 13.9 0.23 10.2 13.9 1.2 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 CDJ65440.1 - 0.2 11.1 7.1 0.28 10.6 7.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Hid1 PF12722.7 CDJ65440.1 - 0.27 9.3 6.6 0.35 9.0 6.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.9 CDJ65440.1 - 0.34 9.1 22.2 0.44 8.8 22.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TERB2 PF15101.6 CDJ65440.1 - 0.35 10.9 9.9 0.71 9.9 9.9 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RR_TM4-6 PF06459.12 CDJ65440.1 - 0.39 10.5 9.2 0.55 10.0 9.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spt20 PF12090.8 CDJ65440.1 - 0.42 10.2 31.8 0.7 9.5 31.8 1.4 1 0 0 1 1 1 0 Spt20 family CLN3 PF02487.17 CDJ65440.1 - 0.49 9.4 3.5 0.81 8.7 3.5 1.3 1 0 0 1 1 1 0 CLN3 protein EPL1 PF10513.9 CDJ65440.1 - 0.62 10.4 10.4 1.2 9.6 10.4 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Neur_chan_memb PF02932.16 CDJ65440.1 - 0.67 10.0 6.7 1.1 9.3 6.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 CDJ65440.1 - 0.71 9.6 6.8 1.2 8.9 6.8 1.3 1 0 0 1 1 1 0 Connexin CPSF100_C PF13299.6 CDJ65440.1 - 1.1 9.5 8.3 2 8.6 8.3 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2828 PF11443.8 CDJ65440.1 - 1.2 7.2 12.0 1.6 6.7 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MAJIN PF15077.6 CDJ65440.1 - 1.5 8.6 11.2 2.2 8.0 11.2 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Tim54 PF11711.8 CDJ65440.1 - 1.6 7.4 11.2 2.3 6.9 11.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Apc15p PF05841.11 CDJ65440.1 - 1.6 9.5 19.6 3.2 8.6 19.6 1.5 1 0 0 1 1 1 0 Apc15p protein MCM_bind PF09739.9 CDJ65440.1 - 2.3 6.6 14.8 3.3 6.0 14.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor GREB1 PF15782.5 CDJ65440.1 - 2.4 5.2 12.5 2.9 4.9 12.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 CDJ65440.1 - 4 6.6 5.2 6.2 5.9 5.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Pannexin_like PF12534.8 CDJ65440.1 - 4 6.4 7.5 6.6 5.7 7.5 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DDRGK PF09756.9 CDJ65440.1 - 8 6.0 16.3 13 5.3 16.3 1.2 1 0 0 1 1 1 0 DDRGK domain NST1 PF13945.6 CDJ65440.1 - 8.4 6.5 19.8 14 5.7 19.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4834 PF16118.5 CDJ65440.1 - 8.5 7.4 13.0 22 6.1 13.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Zip PF02535.22 CDJ65442.1 - 0.9 8.7 9.1 1.5 7.9 9.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4667 PF15700.5 CDJ65443.1 - 0.00023 21.4 3.9 0.00026 21.2 3.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) DUF2722 PF10846.8 CDJ65443.1 - 0.0011 18.1 7.1 0.0013 17.7 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) AF-4 PF05110.13 CDJ65443.1 - 0.004 15.3 10.1 0.0048 15.1 10.1 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Lin-8 PF03353.15 CDJ65443.1 - 0.0056 16.3 2.5 0.007 16.0 2.5 1.0 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ65443.1 - 0.015 15.3 10.7 0.017 15.2 10.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2207 PF09972.9 CDJ65443.1 - 0.032 13.0 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FxsA PF04186.13 CDJ65443.1 - 0.036 14.2 0.3 0.052 13.7 0.3 1.2 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein Apt1 PF10351.9 CDJ65443.1 - 0.057 12.3 3.5 0.064 12.1 3.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMEM51 PF15345.6 CDJ65443.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.0 1 1 1 2 2 1 0 Transmembrane protein 51 Plasmodium_Vir PF05795.11 CDJ65443.1 - 0.56 9.6 1.4 0.65 9.4 1.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CYSTM PF12734.7 CDJ65443.1 - 1.2 9.5 15.9 3.3 8.1 15.9 1.8 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF4131 PF13567.6 CDJ65444.1 - 2 8.1 5.7 1.1 8.9 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TauE PF01925.19 CDJ65445.1 - 0.61 9.7 11.3 0.043 13.5 1.1 2.2 1 1 0 2 2 2 0 Sulfite exporter TauE/SafE DUF3446 PF11928.8 CDJ65445.1 - 1.5 9.2 25.5 2.9 8.2 6.0 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF1645 PF07816.11 CDJ65445.1 - 2 9.0 10.9 11 6.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) AlaDh_PNT_C PF01262.21 CDJ65446.1 - 0.00054 19.3 0.0 0.00064 19.1 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ACP_syn_III PF08545.10 CDJ65448.1 - 5.7e-24 83.8 1.1 5.7e-24 83.8 1.1 2.7 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 CDJ65448.1 - 2.2e-20 72.6 0.0 1.2e-19 70.3 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ribosomal_60s PF00428.19 CDJ65448.1 - 0.045 14.3 5.5 0.045 14.3 5.5 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein Chal_sti_synt_C PF02797.15 CDJ65448.1 - 0.22 11.5 0.0 0.81 9.7 0.0 1.8 1 1 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Clat_adaptor_s PF01217.20 CDJ65450.1 - 0.00014 21.8 0.4 0.00021 21.3 0.4 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.14 CDJ65450.1 - 0.089 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 DUF1631 PF07793.11 CDJ65450.1 - 0.11 10.9 5.6 0.14 10.6 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Adap_comp_sub PF00928.21 CDJ65451.1 - 2.3e-35 122.2 0.0 3.4e-30 105.3 0.0 2.0 1 1 1 2 2 2 2 Adaptor complexes medium subunit family DUF2722 PF10846.8 CDJ65452.1 - 0.00079 18.5 7.2 0.15 11.0 3.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ65452.1 - 0.033 14.2 17.4 0.47 10.4 3.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BatD PF13584.6 CDJ65452.1 - 0.045 12.6 0.7 0.069 11.9 0.7 1.3 1 0 0 1 1 1 0 Oxygen tolerance DUF4242 PF14026.6 CDJ65453.1 - 0.11 12.8 2.8 0.51 10.6 2.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4242) ECM1 PF05782.11 CDJ65454.1 - 0.00067 18.7 9.0 0.00067 18.7 9.0 1.7 2 0 0 2 2 2 1 Extracellular matrix protein 1 (ECM1) DUF2722 PF10846.8 CDJ65454.1 - 0.07 12.1 7.1 0.13 11.2 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 CDJ65454.1 - 0.57 9.1 7.1 0.88 8.5 7.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_60s PF00428.19 CDJ65455.1 - 0.033 14.8 24.4 0.033 14.8 24.4 4.2 4 1 0 4 4 4 0 60s Acidic ribosomal protein Utp14 PF04615.13 CDJ65455.1 - 2.7 6.5 14.4 3.8 6.0 14.4 1.1 1 0 0 1 1 1 0 Utp14 protein Pkinase PF00069.25 CDJ65456.1 - 1.1e-44 152.8 0.0 1.3e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65456.1 - 6.1e-21 74.9 0.0 7.6e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ65456.1 - 0.0011 18.3 0.0 0.0018 17.7 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ65456.1 - 0.074 12.4 0.0 0.46 9.8 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ERM PF00769.19 CDJ65457.1 - 6.1 6.6 16.7 0.16 11.8 9.9 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family SR-25 PF10500.9 CDJ65459.1 - 0.18 11.4 7.1 0.14 11.8 7.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ65459.1 - 4.4 8.0 13.1 3.4 8.4 12.5 1.2 1 1 0 1 1 1 0 Immortalisation up-regulated protein BAF1_ABF1 PF04684.13 CDJ65460.1 - 1.4 7.9 17.9 1.5 7.8 17.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor AAT PF03417.16 CDJ65460.1 - 1.4 8.6 11.6 1.5 8.4 11.6 1.0 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Pex14_N PF04695.13 CDJ65460.1 - 1.5 9.5 22.7 2.2 8.9 22.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region R_equi_Vir PF05526.11 CDJ65460.1 - 2 8.2 8.0 2.6 7.9 8.0 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Lin-8 PF03353.15 CDJ65460.1 - 2.1 7.8 20.3 2.3 7.7 20.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Med15 PF09606.10 CDJ65460.1 - 2.8 6.5 29.4 3.3 6.3 29.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal O-antigen_lig PF13425.6 CDJ65460.1 - 3.1 6.5 10.9 3.3 6.4 10.9 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein TFIIA PF03153.13 CDJ65460.1 - 4.5 7.2 36.4 4.6 7.1 36.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4569 PF15133.6 CDJ65460.1 - 6.6 6.4 21.5 7.6 6.2 21.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Ureide_permease PF07168.11 CDJ65460.1 - 8.6 5.0 7.9 9.9 4.8 7.9 1.2 1 0 0 1 1 1 0 Ureide permease UPF0560 PF10577.9 CDJ65460.1 - 8.9 4.7 19.1 10 4.5 19.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Peptidase_S64 PF08192.11 CDJ65460.1 - 9.4 4.6 21.1 10 4.5 21.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 GpcrRhopsn4 PF10192.9 CDJ65461.1 - 1.7e-07 31.0 1.3 2.2e-07 30.5 1.3 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 CDJ65461.1 - 0.00013 21.3 0.8 0.00017 20.9 0.8 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor MSP1a PF11670.8 CDJ65461.1 - 0.039 13.2 0.4 0.053 12.8 0.4 1.1 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) TMCCDC2 PF15844.5 CDJ65461.1 - 0.65 9.9 3.3 1.1 9.1 0.4 2.1 1 1 1 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 DUF4191 PF13829.6 CDJ65461.1 - 0.78 9.0 2.3 1.2 8.5 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Mt_ATP-synt_B PF05405.14 CDJ65463.1 - 1.4 8.5 7.3 2.8 7.5 1.9 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Spt20 PF12090.8 CDJ65464.1 - 1.6e-05 24.6 23.4 0.00031 20.4 7.0 5.2 4 1 0 4 4 4 3 Spt20 family DUF2722 PF10846.8 CDJ65464.1 - 0.0011 18.0 4.6 0.0011 18.0 4.6 6.4 6 1 1 7 7 7 3 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ65464.1 - 0.0064 16.6 4.8 0.0064 16.6 4.8 4.9 4 2 2 6 6 6 2 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ65464.1 - 0.012 15.7 6.2 0.012 15.7 6.2 8.6 5 2 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 DUF4614 PF15391.6 CDJ65465.1 - 0.056 13.4 15.1 0.07 13.1 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 CDJ65465.1 - 2.2 7.0 14.4 2.3 7.0 14.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain MAP70 PF07058.11 CDJ65465.1 - 4.7 5.8 12.0 4.6 5.9 12.0 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 Cation_ATPase_C PF00689.21 CDJ65466.1 - 3.1e-08 33.5 5.7 3e-07 30.3 2.0 2.3 2 0 0 2 2 2 2 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 CDJ65466.1 - 0.00015 21.6 0.4 0.00025 20.9 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ65466.1 - 0.0051 17.1 0.1 0.0051 17.1 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF515 PF04415.12 CDJ65466.1 - 4.4 5.6 8.0 5.6 5.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Spt20 PF12090.8 CDJ65467.1 - 0.0032 17.1 15.3 0.0032 17.1 15.3 2.3 2 0 0 2 2 2 2 Spt20 family DUF755 PF05501.11 CDJ65467.1 - 0.011 16.0 7.1 0.011 16.0 7.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF755) Na_Ala_symp PF01235.17 CDJ65467.1 - 0.89 8.8 6.9 1.7 7.9 6.9 1.4 1 0 0 1 1 1 0 Sodium:alanine symporter family RrnaAD PF00398.20 CDJ65468.1 - 3.6e-17 62.3 0.0 1.4e-15 57.1 0.0 2.1 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 CDJ65468.1 - 0.00011 22.1 0.4 0.0015 18.4 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ65468.1 - 0.014 16.1 0.0 0.061 14.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF2722 PF10846.8 CDJ65468.1 - 0.021 13.8 0.7 0.062 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) NodS PF05401.11 CDJ65468.1 - 0.037 13.6 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF4441 PF14536.6 CDJ65468.1 - 0.068 13.4 0.6 0.13 12.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Methyltransf_11 PF08241.12 CDJ65468.1 - 0.11 13.1 0.0 0.51 11.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain SUIM_assoc PF16619.5 CDJ65468.1 - 0.89 9.7 22.6 0.57 10.3 9.1 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 CDJ65468.1 - 1.4 9.8 16.0 9.6 7.1 9.9 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Med3 PF11593.8 CDJ65468.1 - 2.4 7.2 11.6 0.082 12.1 2.5 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal GET2 PF08690.10 CDJ65469.1 - 0.18 11.5 0.0 0.18 11.5 0.0 6.9 4 2 2 6 6 6 0 GET complex subunit GET2 Med15 PF09606.10 CDJ65469.1 - 6.6 5.3 164.9 0.16 10.6 9.2 3.6 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.13 CDJ65470.1 - 0.00095 18.4 21.0 0.00095 18.4 21.0 1.9 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor SID-1_RNA_chan PF13965.6 CDJ65470.1 - 0.17 10.2 6.6 0.24 9.8 6.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RskA PF10099.9 CDJ65470.1 - 1 9.6 107.6 17 5.7 11.2 5.1 1 1 2 3 3 3 0 Anti-sigma-K factor rskA LMBR1 PF04791.16 CDJ65470.1 - 1.2 8.0 10.9 0.014 14.3 3.7 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein Actin PF00022.19 CDJ65471.1 - 3.9e-24 85.0 0.2 1.6e-15 56.6 0.1 3.0 1 1 1 2 2 2 2 Actin IMUP PF15761.5 CDJ65471.1 - 1.7 9.3 39.3 0.18 12.5 2.2 4.1 4 0 0 4 4 4 0 Immortalisation up-regulated protein DUF908 PF06012.12 CDJ65471.1 - 1.8 7.9 7.7 1.4 8.3 0.2 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF908) Helicase_C PF00271.31 CDJ65473.1 - 2.1e-14 53.8 0.1 1.8e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3240 PF11582.8 CDJ65473.1 - 0.028 14.6 0.2 0.83 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3240) Spt20 PF12090.8 CDJ65473.1 - 0.27 10.8 5.6 0.53 9.9 5.6 1.5 1 0 0 1 1 1 0 Spt20 family GREB1 PF15782.5 CDJ65473.1 - 5.1 4.1 4.8 7.8 3.5 4.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CDJ65474.1 - 0.0026 17.8 37.1 0.0026 17.8 37.1 2.5 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PreAtp-grasp PF18604.1 CDJ65474.1 - 0.74 9.5 7.3 0.037 13.7 0.9 2.1 2 0 0 2 2 2 0 Pre ATP-grasp domain DUF4786 PF16027.5 CDJ65474.1 - 5.3 7.6 9.7 2.8 8.5 6.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4786) CPW_WPC PF09717.10 CDJ65476.1 - 1.5e-47 160.3 14.8 2e-11 44.7 2.5 5.3 5 0 0 5 5 5 5 Plasmodium falciparum domain of unknown function (CPW_WPC) IMUP PF15761.5 CDJ65476.1 - 0.25 12.0 8.6 1.7 9.4 8.6 2.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ65476.1 - 7.9 6.0 18.4 0.74 9.4 12.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cullin_binding PF03556.15 CDJ65477.1 - 4.3e-22 78.8 0.6 2.1e-14 54.0 0.0 2.2 2 0 0 2 2 2 2 Cullin binding SR-25 PF10500.9 CDJ65477.1 - 9.5 5.8 16.5 14 5.2 16.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3995 PF13160.6 CDJ65478.1 - 0.27 11.6 11.9 0.8 10.1 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) PH_BEACH PF14844.6 CDJ65479.1 - 0.1 12.7 0.3 0.35 11.0 0.3 1.9 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Peptidase_C10 PF01640.17 CDJ65479.1 - 5.8 7.2 6.6 15 5.8 6.6 1.6 1 0 0 1 1 1 0 Peptidase C10 family DEAD PF00270.29 CDJ65480.1 - 7e-37 126.9 0.0 1.5e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DivIC PF04977.15 CDJ65482.1 - 0.0081 15.9 6.3 0.01 15.6 6.3 1.1 1 0 0 1 1 1 1 Septum formation initiator TMEM51 PF15345.6 CDJ65482.1 - 0.0083 16.0 0.7 0.0083 16.0 0.7 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 Spt20 PF12090.8 CDJ65482.1 - 0.0096 15.6 13.2 0.0099 15.5 13.2 1.1 1 0 0 1 1 1 1 Spt20 family DUF4834 PF16118.5 CDJ65482.1 - 0.012 16.6 1.3 0.012 16.6 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ65482.1 - 0.013 14.5 10.4 0.013 14.5 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) XRN_N PF03159.18 CDJ65482.1 - 0.023 14.1 2.0 0.022 14.2 2.0 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus RAB3GAP2_N PF14655.6 CDJ65482.1 - 0.023 14.0 0.3 0.024 13.9 0.3 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus G0-G1_switch_2 PF15103.6 CDJ65482.1 - 0.04 14.3 0.9 0.043 14.2 0.9 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 OPA3 PF07047.12 CDJ65482.1 - 0.055 13.2 1.8 0.079 12.7 1.8 1.2 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF3767 PF12597.8 CDJ65482.1 - 0.13 12.1 1.2 0.17 11.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Roughex PF06020.11 CDJ65482.1 - 0.14 11.3 2.9 0.13 11.4 2.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Baculo_PP31 PF05311.11 CDJ65482.1 - 0.19 11.2 3.8 0.24 10.9 3.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) PepSY_TM PF03929.16 CDJ65482.1 - 0.2 11.3 0.4 0.21 11.2 0.4 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Rrn6 PF10214.9 CDJ65482.1 - 0.25 9.8 10.4 0.27 9.7 10.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TMEM208_SND2 PF05620.11 CDJ65482.1 - 0.27 11.0 2.2 0.34 10.7 2.2 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Androgen_recep PF02166.16 CDJ65482.1 - 0.37 9.6 9.4 0.32 9.8 9.4 1.1 1 0 0 1 1 1 0 Androgen receptor Med3 PF11593.8 CDJ65482.1 - 0.58 9.3 11.2 0.6 9.2 11.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal tRNA-synt_1 PF00133.22 CDJ65483.1 - 3.5e-14 52.0 0.0 4.1e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Crust_neuro_H PF03858.13 CDJ65484.1 - 0.43 11.4 6.8 11 6.9 0.3 4.5 3 0 0 3 3 3 0 Crustacean neurohormone H Presenilin PF01080.17 CDJ65486.1 - 6 5.5 40.1 6.9 5.3 40.1 1.0 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 CDJ65486.1 - 8.6 5.6 36.2 8.9 5.6 36.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MCM_bind PF09739.9 CDJ65486.1 - 9.1 4.6 28.9 10 4.4 28.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor VIT1 PF01988.19 CDJ65489.1 - 0.0084 16.0 11.7 0.0084 16.0 11.7 2.0 2 0 0 2 2 2 1 VIT family Macoilin PF09726.9 CDJ65489.1 - 0.56 8.7 23.9 0.74 8.3 23.9 1.2 1 0 0 1 1 1 0 Macoilin family Mitofilin PF09731.9 CDJ65489.1 - 2.4 6.9 39.9 3.8 6.2 39.9 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3292 PF11696.8 CDJ65489.1 - 7.4 4.8 21.1 9.2 4.5 21.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Cellulose_synt PF03552.14 CDJ65489.1 - 7.6 4.9 6.4 10 4.5 6.4 1.2 1 0 0 1 1 1 0 Cellulose synthase RRM_1 PF00076.22 CDJ65491.1 - 2.2e-07 30.6 0.0 6.6e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF1G PF00647.19 CDJ65492.1 - 8e-28 96.6 1.1 6.1e-25 87.4 0.1 2.5 2 0 0 2 2 2 2 Elongation factor 1 gamma, conserved domain Carb_anhydrase PF00194.21 CDJ65492.1 - 4.5e-25 88.6 0.1 5.2e-22 78.6 0.1 3.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase GST_C PF00043.25 CDJ65492.1 - 3.8e-09 36.6 0.3 3.8e-09 36.6 0.3 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDJ65492.1 - 2.7e-06 27.5 0.2 7.3e-06 26.1 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ65492.1 - 1.4e-05 25.0 2.4 1.4e-05 25.0 2.4 2.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF2722 PF10846.8 CDJ65492.1 - 0.00073 18.6 3.0 0.00073 18.6 3.0 4.2 3 1 0 3 3 2 2 Protein of unknown function (DUF2722) GST_N_3 PF13417.6 CDJ65492.1 - 0.0021 18.4 0.0 0.0052 17.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SUIM_assoc PF16619.5 CDJ65492.1 - 0.0053 16.8 1.9 0.0053 16.8 1.9 5.7 4 1 0 4 4 2 2 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ65492.1 - 0.012 15.6 54.2 0.32 11.0 10.1 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Ctf8 PF09696.10 CDJ65492.1 - 1 9.7 12.3 2.9 8.2 0.7 3.2 3 0 0 3 3 3 0 Ctf8 Med15 PF09606.10 CDJ65492.1 - 1.8 7.2 51.6 0.93 8.1 18.1 3.2 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Raftlin PF15250.6 CDJ65493.1 - 0.76 8.5 9.1 0.85 8.3 9.1 1.0 1 0 0 1 1 1 0 Raftlin V_ATPase_I PF01496.19 CDJ65493.1 - 0.95 7.3 6.0 1 7.2 6.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PsbQ PF05757.11 CDJ65493.1 - 9.9 5.8 11.0 8.8 6.0 2.6 2.0 1 1 1 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) SR-25 PF10500.9 CDJ65494.1 - 0.00087 19.0 1.3 0.00087 19.0 1.3 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein TAF8_C PF10406.9 CDJ65494.1 - 0.0014 19.2 0.1 0.0014 19.2 0.1 2.6 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term eIF-3_zeta PF05091.12 CDJ65494.1 - 0.45 9.4 6.2 0.5 9.3 6.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ65494.1 - 2 9.5 7.3 1.9 9.5 5.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ65494.1 - 2 7.3 19.5 4.4 6.1 19.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SARAF PF06682.12 CDJ65494.1 - 2.5 7.7 20.1 2.5 7.7 1.7 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis IMUP PF15761.5 CDJ65495.1 - 8.1e-05 23.3 4.7 8.8e-05 23.2 4.7 1.1 1 0 0 1 1 1 1 Immortalisation up-regulated protein SUZ PF12752.7 CDJ65495.1 - 0.034 14.9 3.0 0.045 14.5 3.0 1.2 1 0 0 1 1 1 0 SUZ domain SR-25 PF10500.9 CDJ65495.1 - 0.039 13.6 11.5 0.046 13.3 11.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CDJ65495.1 - 5.7 5.1 4.5 5.7 5.1 4.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2722 PF10846.8 CDJ65496.1 - 0.015 14.2 0.6 0.015 14.2 0.6 7.1 5 1 1 6 6 6 0 Protein of unknown function (DUF2722) DUF3810 PF12725.7 CDJ65496.1 - 0.045 13.1 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) MFS_1 PF07690.16 CDJ65497.1 - 0.00019 20.5 7.3 0.00056 18.9 7.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily SR-25 PF10500.9 CDJ65497.1 - 0.036 13.7 7.1 0.057 13.0 7.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF5470 PF17564.2 CDJ65497.1 - 4.6 7.5 5.3 8.8 6.6 5.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5470) DUF755 PF05501.11 CDJ65497.1 - 4.7 7.5 12.7 7.4 6.9 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4064 PF13273.6 CDJ65499.1 - 0.21 11.9 9.3 0.43 10.9 0.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) TniB PF05621.11 CDJ65500.1 - 2.2e-05 23.9 0.2 4.4e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 CDJ65500.1 - 8.8e-05 22.8 2.2 8.8e-05 22.8 2.2 1.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ65500.1 - 0.0057 17.1 26.1 0.0057 17.1 26.1 3.1 3 3 1 4 4 4 1 AAA ATPase domain SUIM_assoc PF16619.5 CDJ65500.1 - 0.0081 16.2 5.1 0.0081 16.2 5.1 4.1 4 0 0 4 4 3 1 Unstructured region C-term to UIM in Ataxin3 DUF3446 PF11928.8 CDJ65500.1 - 0.0098 16.2 6.2 0.0098 16.2 6.2 4.0 4 0 0 4 4 4 2 Early growth response N-terminal domain ABC_tran PF00005.27 CDJ65500.1 - 0.011 16.2 0.2 0.021 15.3 0.2 1.5 1 0 0 1 1 1 0 ABC transporter ORC4_C PF14629.6 CDJ65500.1 - 0.025 13.9 0.0 0.025 13.9 0.0 2.1 3 0 0 3 3 3 0 Origin recognition complex (ORC) subunit 4 C-terminus DUF1645 PF07816.11 CDJ65500.1 - 0.082 13.5 15.6 0.15 12.6 1.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ65500.1 - 0.085 12.5 30.5 0.4 10.3 11.8 2.9 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF935 PF06074.12 CDJ65500.1 - 3.2 6.4 10.6 6 5.5 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF935) DUF4667 PF15700.5 CDJ65500.1 - 6.1 6.9 16.7 3.3 7.7 0.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4667) YchF-GTPase_C PF06071.13 CDJ65501.1 - 3.1e-41 139.5 0.5 8.9e-41 138.0 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CDJ65501.1 - 2.4e-20 72.7 0.0 1.3e-19 70.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ65501.1 - 4e-06 26.4 0.0 1.5e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.6 CDJ65501.1 - 0.027 15.0 1.2 4.7 7.8 0.0 3.1 3 1 2 5 5 5 0 AAA domain PEP-utilisers_N PF05524.13 CDJ65501.1 - 0.032 14.4 0.4 0.084 13.1 0.4 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal TGS PF02824.21 CDJ65501.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 TGS domain eIF3_N PF09440.10 CDJ65501.1 - 0.58 10.6 3.9 0.82 10.1 2.8 1.8 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain Pkinase PF00069.25 CDJ65502.1 - 2.2e-75 253.4 0.1 1.2e-74 251.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65502.1 - 1.7e-38 132.4 0.0 4.2e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ65502.1 - 4.7e-05 23.4 0.1 4.7e-05 23.4 0.1 4.3 3 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ65502.1 - 0.0003 20.2 0.6 0.0003 20.2 0.6 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ65502.1 - 0.00096 18.2 0.4 0.00096 18.2 0.4 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Choline_kinase PF01633.20 CDJ65502.1 - 0.16 11.5 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase HGTP_anticodon2 PF12745.7 CDJ65503.1 - 0.081 12.4 1.5 0.14 11.6 1.5 1.5 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF4011 PF13195.6 CDJ65503.1 - 0.1 12.5 0.5 0.18 11.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) GldM_N PF12081.8 CDJ65503.1 - 0.11 12.6 1.5 0.18 11.8 1.5 1.3 1 0 0 1 1 1 0 GldM N-terminal domain ADIP PF11559.8 CDJ65503.1 - 0.13 12.4 3.8 0.22 11.6 3.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 CDJ65503.1 - 1 7.2 2.2 1.4 6.8 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tmemb_cc2 PF10267.9 CDJ65504.1 - 0.00097 18.4 6.6 0.00097 18.4 6.6 2.2 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein TSC22 PF01166.18 CDJ65504.1 - 0.12 12.7 4.1 0.1 12.9 1.5 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF4423 PF14394.6 CDJ65504.1 - 0.41 10.3 9.6 0.12 12.0 4.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4423) HALZ PF02183.18 CDJ65504.1 - 0.44 10.8 5.7 0.082 13.1 0.9 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper CbiG_C PF01890.16 CDJ65504.1 - 0.83 10.2 5.2 1 10.0 2.7 2.3 2 0 0 2 2 2 0 Cobalamin synthesis G C-terminus Ntox25 PF15530.6 CDJ65505.1 - 0.014 15.5 0.5 0.044 14.0 0.4 1.8 1 1 0 1 1 1 0 Bacterial toxin 25 Topoisom_bac PF01131.20 CDJ65506.1 - 6.7e-06 25.4 0.1 0.029 13.4 0.0 2.1 1 1 1 2 2 2 2 DNA topoisomerase Pkinase PF00069.25 CDJ65507.1 - 2.6e-33 115.5 0.0 3.6e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65507.1 - 1.5e-15 57.2 0.0 2.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 CDJ65507.1 - 6.4e-12 45.8 0.5 6.1e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ65507.1 - 4.8e-08 32.0 1.0 0.0024 17.3 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CDJ65507.1 - 4.8e-08 32.3 1.3 0.0019 18.0 0.2 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CDJ65507.1 - 3e-07 30.2 0.9 3.2e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ65507.1 - 5.9e-07 28.7 4.3 0.0014 18.0 0.6 2.9 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.6 CDJ65507.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Dockerin_1 PF00404.18 CDJ65507.1 - 0.18 12.1 1.4 2.3 8.5 1.2 2.4 1 1 1 2 2 2 0 Dockerin type I domain Miga PF10265.9 CDJ65508.1 - 1.5 7.7 5.1 3.5 6.5 5.1 1.6 1 0 0 1 1 1 0 Mitoguardin Dcc1 PF09724.9 CDJ65509.1 - 1.4e-12 47.6 0.0 1.1e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 Sister chromatid cohesion protein Dcc1 FAD_binding_3 PF01494.19 CDJ65510.1 - 4.1e-60 203.9 3.8 1.3e-30 106.8 0.6 4.0 4 0 0 4 4 4 3 FAD binding domain FAD_binding_2 PF00890.24 CDJ65510.1 - 6.5e-05 22.2 0.2 0.00017 20.8 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CDJ65510.1 - 7.2e-05 22.0 0.1 0.00015 21.0 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CDJ65510.1 - 0.0004 20.1 0.2 0.0014 18.3 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDJ65510.1 - 0.00056 19.2 0.0 0.00096 18.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDJ65510.1 - 0.0012 19.0 0.6 0.0045 17.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CDJ65510.1 - 0.0028 16.9 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ65510.1 - 0.0033 16.7 0.2 0.006 15.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CDJ65510.1 - 0.0085 14.8 0.1 0.016 14.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein ThiF PF00899.21 CDJ65510.1 - 0.13 11.6 0.4 13 5.0 0.0 2.4 2 0 0 2 2 2 0 ThiF family Ndc1_Nup PF09531.10 CDJ65510.1 - 6 5.4 7.3 17 3.9 7.3 1.7 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 CDJ65511.1 - 1e-22 80.8 0.0 1.3e-10 41.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65511.1 - 1.1e-09 37.9 0.0 1.1e-05 24.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pro_dh PF01619.18 CDJ65512.1 - 8.5e-65 219.2 0.0 1e-63 215.6 0.0 2.1 2 0 0 2 2 2 1 Proline dehydrogenase TFIIA PF03153.13 CDJ65512.1 - 2.7 7.9 9.2 1.5 8.7 4.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ANAPC_CDC26 PF10471.9 CDJ65512.1 - 4.4 8.2 18.2 0.31 11.9 0.6 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Mem_trans PF03547.18 CDJ65513.1 - 0.088 11.2 1.2 0.14 10.5 1.2 1.5 1 0 0 1 1 1 0 Membrane transport protein DDHD PF02862.17 CDJ65513.1 - 0.14 12.3 16.9 0.056 13.6 11.0 2.4 2 0 0 2 2 2 0 DDHD domain CDC45 PF02724.14 CDJ65513.1 - 0.21 9.8 16.1 0.34 9.2 16.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Otopetrin PF03189.13 CDJ65513.1 - 0.38 9.5 8.4 0.031 13.1 4.2 1.4 2 0 0 2 2 2 0 Otopetrin HCO3_cotransp PF00955.21 CDJ65513.1 - 1.1 8.1 11.7 1.6 7.5 11.7 1.2 1 0 0 1 1 1 0 HCO3- transporter family MMR1 PF08505.10 CDJ65513.1 - 1.4 9.1 28.7 0.064 13.5 20.5 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein NPR3 PF03666.13 CDJ65513.1 - 1.6 7.4 19.3 2.8 6.7 19.3 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MDM10 PF12519.8 CDJ65513.1 - 2.5 6.9 20.8 3.2 6.5 18.2 2.1 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 LptF_LptG PF03739.14 CDJ65513.1 - 5.1 5.8 11.4 7.9 5.2 11.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG BORG_CEP PF14957.6 CDJ65513.1 - 7.9 7.7 16.8 1.2 10.3 11.4 2.3 2 0 0 2 2 2 0 Cdc42 effector PBP1_TM PF14812.6 CDJ65513.1 - 9.5 6.7 10.8 23 5.4 10.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RskA PF10099.9 CDJ65514.1 - 0.007 16.7 17.4 0.007 16.7 17.4 3.0 1 1 1 2 2 2 1 Anti-sigma-K factor rskA PI3K_1B_p101 PF10486.9 CDJ65514.1 - 0.35 8.6 15.3 0.4 8.4 15.3 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pinin_SDK_memA PF04696.13 CDJ65514.1 - 0.58 10.2 38.7 0.62 10.1 11.4 2.4 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF4770 PF15994.5 CDJ65514.1 - 1.6 8.9 27.2 0.12 12.6 5.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Miff PF05644.11 CDJ65514.1 - 2.4 7.7 22.5 2.9 7.5 22.5 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Apt1 PF10351.9 CDJ65514.1 - 4.8 5.9 15.9 5.6 5.7 15.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CAF1 PF04857.20 CDJ65514.1 - 6.1 5.9 13.3 8.5 5.4 13.3 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease Ndc1_Nup PF09531.10 CDJ65514.1 - 7 5.2 28.8 7.7 5.1 28.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Eapp_C PF10238.9 CDJ65514.1 - 8.2 6.5 27.2 0.52 10.4 4.7 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF2722 PF10846.8 CDJ65515.1 - 0.007 15.4 14.8 0.007 15.4 14.8 3.2 2 1 0 2 2 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ65515.1 - 0.0091 15.6 21.6 0.0091 15.6 21.6 3.1 2 1 0 2 2 1 1 Spt20 family Sporozoite_P67 PF05642.11 CDJ65515.1 - 0.0092 14.1 0.1 0.0092 14.1 0.1 2.0 2 0 0 2 2 2 1 Sporozoite P67 surface antigen DUF572 PF04502.13 CDJ65515.1 - 0.0096 15.6 31.2 0.024 14.3 13.8 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF572) EPL1 PF10513.9 CDJ65515.1 - 0.011 16.1 4.8 0.011 16.1 4.8 2.7 2 1 0 2 2 1 0 Enhancer of polycomb-like Kelch_1 PF01344.25 CDJ65515.1 - 0.028 14.0 1.2 2.4 7.8 0.0 2.6 2 0 0 2 2 2 0 Kelch motif MMR1 PF08505.10 CDJ65515.1 - 0.049 13.9 30.1 0.54 10.5 9.8 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein PDZ_2 PF13180.6 CDJ65515.1 - 0.07 13.5 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 PDZ domain Draxin PF15550.6 CDJ65515.1 - 0.081 12.8 21.2 0.084 12.7 4.8 2.1 2 0 0 2 2 2 0 Draxin Kelch_4 PF13418.6 CDJ65515.1 - 0.083 12.9 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain PAT1 PF09770.9 CDJ65515.1 - 0.12 10.6 45.4 0.25 9.5 20.4 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF3801 PF12687.7 CDJ65515.1 - 0.12 12.4 26.8 0.47 10.5 8.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) SOBP PF15279.6 CDJ65515.1 - 0.16 12.6 24.0 0.76 10.3 9.3 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein DUF3807 PF12720.7 CDJ65515.1 - 0.17 12.2 41.2 0.3 11.3 12.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Presenilin PF01080.17 CDJ65515.1 - 0.24 10.1 37.3 0.12 11.1 14.1 2.1 2 0 0 2 2 2 0 Presenilin CDC45 PF02724.14 CDJ65515.1 - 0.35 9.1 27.6 0.82 7.9 7.3 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF4175 PF13779.6 CDJ65515.1 - 0.5 8.2 60.6 0.054 11.4 28.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) NST1 PF13945.6 CDJ65515.1 - 0.58 10.2 42.5 1.2 9.2 19.1 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator Kelch_3 PF13415.6 CDJ65515.1 - 0.59 10.5 0.0 0.59 10.5 0.0 3.8 5 0 0 5 5 3 0 Galactose oxidase, central domain PA26 PF04636.13 CDJ65515.1 - 0.62 8.9 24.0 0.58 9.0 10.6 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Lin-8 PF03353.15 CDJ65515.1 - 0.7 9.4 31.8 1.5 8.3 12.7 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Hamartin PF04388.12 CDJ65515.1 - 0.75 8.4 21.6 0.17 10.6 7.4 2.0 2 0 0 2 2 2 0 Hamartin protein CNDH2_C PF16858.5 CDJ65515.1 - 0.79 9.5 29.0 0.83 9.5 6.7 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Band_3_cyto PF07565.13 CDJ65515.1 - 1.6 8.5 27.6 2.5 7.8 7.1 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain SAGA-Tad1 PF12767.7 CDJ65515.1 - 1.9 8.2 23.1 2.8 7.6 3.7 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Atg14 PF10186.9 CDJ65515.1 - 2 7.4 35.8 1.1 8.2 18.5 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Gti1_Pac2 PF09729.9 CDJ65515.1 - 2.4 8.2 24.1 5.1 7.2 9.4 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family SLC12 PF03522.15 CDJ65515.1 - 2.7 6.9 29.8 1.2 8.1 7.4 2.1 2 0 0 2 2 2 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ65515.1 - 3.1 6.1 10.6 1.4 7.2 0.4 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 BAF1_ABF1 PF04684.13 CDJ65515.1 - 3.1 6.7 32.5 1.2 8.1 9.8 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor AF-4 PF05110.13 CDJ65515.1 - 3.3 5.7 31.8 1.1 7.3 8.5 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DUF2052 PF09747.9 CDJ65515.1 - 4.1 7.5 35.6 4.9 7.2 13.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF913 PF06025.12 CDJ65515.1 - 4.1 6.3 20.4 3.3 6.6 6.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FHIPEP PF00771.20 CDJ65515.1 - 5.7 5.3 22.8 3.7 5.9 4.9 2.1 2 0 0 2 2 2 0 FHIPEP family FAM176 PF14851.6 CDJ65515.1 - 5.8 6.6 22.1 2.9 7.6 6.0 2.4 2 0 0 2 2 2 0 FAM176 family FAM91_C PF14648.6 CDJ65515.1 - 6.6 5.5 15.0 2.6 6.8 2.9 2.2 2 0 0 2 2 2 0 FAM91 C-terminus Neur_chan_memb PF02932.16 CDJ65515.1 - 6.9 6.7 28.4 6.4 6.7 6.5 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ65515.1 - 7.5 6.3 35.6 4 7.2 12.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CRT10 PF08728.10 CDJ65515.1 - 7.5 4.6 7.8 8.8 4.3 0.5 1.9 2 0 0 2 2 2 0 CRT10 PRP1_N PF06424.12 CDJ65515.1 - 7.6 6.9 30.6 6.1 7.2 12.0 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal FAM76 PF16046.5 CDJ65515.1 - 9 5.6 33.5 1.2 8.5 8.8 2.2 2 0 0 2 2 2 0 FAM76 protein XRN_M PF17846.1 CDJ65517.1 - 5.5 5.8 21.2 5.8 5.8 21.2 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Peptidase_M29 PF02073.15 CDJ65517.1 - 6.9 5.3 14.1 7.6 5.2 14.1 1.0 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) FAM60A PF15396.6 CDJ65517.1 - 7.8 6.4 19.5 8.7 6.3 19.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A YL1 PF05764.13 CDJ65518.1 - 2.8e-17 63.7 38.0 2.8e-17 63.7 38.0 2.3 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 CDJ65518.1 - 3.6e-09 36.2 0.1 5.7e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain PAT1 PF09770.9 CDJ65518.1 - 0.27 9.5 43.3 0.48 8.6 43.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Red1 PF07964.11 CDJ65518.1 - 0.55 8.4 23.0 0.69 8.1 23.0 1.1 1 0 0 1 1 1 0 Rec10 / Red1 TFIIA PF03153.13 CDJ65519.1 - 0.012 15.7 28.4 0.016 15.2 28.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ65519.1 - 0.015 14.1 29.1 0.017 13.9 29.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal VIT1 PF01988.19 CDJ65519.1 - 0.31 10.9 5.9 0.43 10.4 5.9 1.2 1 0 0 1 1 1 0 VIT family DUF2072 PF09845.9 CDJ65519.1 - 0.78 10.0 5.3 1.3 9.3 5.3 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein PAT1 PF09770.9 CDJ65519.1 - 1.8 6.8 27.7 2 6.6 27.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ65519.1 - 7.5 5.2 13.8 9.6 4.9 13.8 1.1 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ65520.1 - 2.2 7.8 43.3 0.032 13.8 9.5 3.3 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein DUF4667 PF15700.5 CDJ65520.1 - 3.2 7.8 27.2 0.04 14.0 2.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) ATP-synt_ab_N PF02874.23 CDJ65524.1 - 0.0017 18.8 0.5 0.0025 18.3 0.5 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_60s PF00428.19 CDJ65524.1 - 7.2 7.3 10.8 15 6.2 10.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein XRN_M PF17846.1 CDJ65525.1 - 1.6e-45 155.9 1.1 1e-27 97.2 0.0 5.0 4 1 1 5 5 5 2 Xrn1 helical domain XRN_N PF03159.18 CDJ65525.1 - 8.3e-10 38.5 0.0 8.3e-10 38.5 0.0 4.8 5 0 0 5 5 5 1 XRN 5'-3' exonuclease N-terminus BPS1 PF05633.11 CDJ65525.1 - 0.0017 17.4 5.6 0.0017 17.4 5.6 2.2 2 0 0 2 2 2 1 Protein BYPASS1-related TFIIA PF03153.13 CDJ65525.1 - 0.087 12.8 79.1 0.32 11.0 18.3 4.1 4 0 0 4 4 4 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ65525.1 - 0.25 11.6 0.0 0.25 11.6 0.0 6.2 3 2 3 6 6 6 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ65525.1 - 0.72 9.4 78.9 0.095 12.3 12.9 4.2 4 0 0 4 4 4 0 Spt20 family XRN_N PF03159.18 CDJ65526.1 - 2.7e-11 43.4 21.9 3.1e-08 33.3 21.9 3.0 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Presenilin PF01080.17 CDJ65526.1 - 0.014 14.2 18.2 0.015 14.1 18.2 1.0 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 CDJ65526.1 - 0.041 12.3 10.5 0.043 12.3 10.5 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor ATF7IP_BD PF16788.5 CDJ65526.1 - 0.054 13.6 15.0 0.065 13.3 15.0 1.0 1 0 0 1 1 1 0 ATF-interacting protein binding domain SUV3_C PF12513.8 CDJ65526.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Suf PF05843.14 CDJ65526.1 - 0.089 12.8 20.7 0.12 12.3 20.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ARF7EP_C PF14949.6 CDJ65526.1 - 0.12 13.1 17.8 0.061 13.9 14.7 1.9 1 1 1 2 2 2 0 ARF7 effector protein C-terminus DUF913 PF06025.12 CDJ65526.1 - 0.13 11.3 8.7 0.15 11.0 8.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM60A PF15396.6 CDJ65526.1 - 0.14 12.2 13.5 0.18 11.8 13.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Spore_coat_CotO PF14153.6 CDJ65526.1 - 0.15 12.0 23.9 0.19 11.6 23.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Macoilin PF09726.9 CDJ65526.1 - 0.18 10.3 9.8 0.19 10.2 9.8 1.0 1 0 0 1 1 1 0 Macoilin family Pex14_N PF04695.13 CDJ65526.1 - 0.19 12.4 29.6 0.26 11.9 29.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ65526.1 - 0.2 11.6 42.2 0.24 11.4 42.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CDJ65526.1 - 0.33 9.6 14.5 0.36 9.5 14.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Velvet PF11754.8 CDJ65526.1 - 0.38 10.7 20.4 0.46 10.4 20.4 1.0 1 0 0 1 1 1 0 Velvet factor AF-4 PF05110.13 CDJ65526.1 - 0.39 8.8 22.7 0.45 8.5 22.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4228 PF14009.6 CDJ65526.1 - 0.41 11.0 8.1 0.6 10.5 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Zip PF02535.22 CDJ65526.1 - 0.44 9.7 8.8 0.49 9.6 8.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 CDJ65526.1 - 0.44 9.9 9.5 0.67 9.3 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Dsh_C PF12316.8 CDJ65526.1 - 0.47 10.8 16.4 0.56 10.6 16.4 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Raftlin PF15250.6 CDJ65526.1 - 0.6 8.8 17.6 0.7 8.6 17.6 1.0 1 0 0 1 1 1 0 Raftlin PARM PF17061.5 CDJ65526.1 - 0.67 10.0 10.2 0.82 9.7 10.2 1.0 1 0 0 1 1 1 0 PARM Neur_chan_memb PF02932.16 CDJ65526.1 - 0.7 9.9 11.6 0.84 9.6 11.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOG2 PF10428.9 CDJ65526.1 - 0.8 8.8 15.9 0.92 8.6 15.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 CDJ65526.1 - 1.1 8.1 11.7 1.2 7.9 11.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spc7_N PF15402.6 CDJ65526.1 - 1.1 7.4 24.8 1.4 7.1 24.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Endostatin PF06482.11 CDJ65526.1 - 1.2 8.5 15.5 1.4 8.3 15.5 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin MAJIN PF15077.6 CDJ65526.1 - 1.3 8.7 10.0 1.6 8.5 10.0 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Bul1_N PF04425.12 CDJ65526.1 - 1.4 7.6 11.2 1.7 7.3 11.2 1.2 1 0 0 1 1 1 0 Bul1 N terminus DUF2052 PF09747.9 CDJ65526.1 - 1.5 8.9 19.3 1.9 8.6 19.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) V_ATPase_I PF01496.19 CDJ65526.1 - 1.6 6.5 13.6 1.9 6.3 13.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAP_alpha PF03896.16 CDJ65526.1 - 2 7.6 9.3 2.4 7.3 9.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Rtf2 PF04641.12 CDJ65526.1 - 2.1 7.6 14.9 2.8 7.2 14.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger PA26 PF04636.13 CDJ65526.1 - 2.1 7.2 11.8 2.5 6.9 11.8 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CBP_BcsG PF11658.8 CDJ65526.1 - 2.6 6.3 10.3 3.4 6.0 10.3 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Dicty_REP PF05086.12 CDJ65526.1 - 2.8 5.8 11.3 3.1 5.7 11.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2828 PF11443.8 CDJ65526.1 - 2.9 5.9 12.8 3.5 5.6 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CCSAP PF15748.5 CDJ65526.1 - 3 8.0 24.7 3.8 7.6 24.7 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 CDJ65526.1 - 3.3 5.9 17.6 3.9 5.6 17.6 1.0 1 0 0 1 1 1 0 CDC45-like protein STAC2_u1 PF16664.5 CDJ65526.1 - 3.4 8.1 18.7 4.3 7.8 18.7 1.1 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 PAT1 PF09770.9 CDJ65526.1 - 3.6 5.7 28.5 4.3 5.5 28.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tsg PF04668.12 CDJ65526.1 - 3.8 8.2 15.6 10 6.8 12.4 2.0 1 1 1 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region DUF4045 PF13254.6 CDJ65526.1 - 3.8 7.0 21.6 4.7 6.8 21.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RR_TM4-6 PF06459.12 CDJ65526.1 - 4 7.2 20.9 5 6.9 20.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 CDJ65526.1 - 4 5.4 21.3 4.8 5.2 21.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SWI-SNF_Ssr4 PF08549.10 CDJ65526.1 - 5 5.6 22.3 6.2 5.3 22.3 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) GREB1 PF15782.5 CDJ65526.1 - 5.2 4.0 20.7 6.2 3.8 20.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 CDJ65526.1 - 5.7 5.9 18.7 6.8 5.6 18.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Sec62 PF03839.16 CDJ65526.1 - 5.7 6.4 12.5 7.8 5.9 12.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2370 PF10176.9 CDJ65526.1 - 5.8 6.5 9.6 7.5 6.1 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) XRN_M PF17846.1 CDJ65526.1 - 6 5.7 14.4 6.8 5.5 14.4 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DUF4551 PF15087.6 CDJ65526.1 - 6.9 5.4 15.6 8.2 5.1 15.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) eIF-3_zeta PF05091.12 CDJ65526.1 - 7.1 5.5 20.8 9 5.1 20.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hydin_ADK PF17213.3 CDJ65526.1 - 7.2 6.8 16.1 11 6.2 16.1 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF2126 PF09899.9 CDJ65526.1 - 7.5 4.5 10.9 8.7 4.3 10.9 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) THOC2_N PF16134.5 CDJ65526.1 - 7.6 5.0 14.7 9.8 4.7 14.7 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Hamartin PF04388.12 CDJ65526.1 - 8.4 4.9 18.8 9.7 4.7 18.8 1.0 1 0 0 1 1 1 0 Hamartin protein DUF5427 PF10310.9 CDJ65526.1 - 8.6 5.2 24.5 10 4.9 24.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4192 PF13830.6 CDJ65526.1 - 9.6 6.2 10.8 11 6.0 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Pkinase PF00069.25 CDJ65527.1 - 9.8e-25 87.4 0.0 1.4e-12 47.6 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65527.1 - 1.7e-10 40.6 0.0 0.00025 20.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Ras PF00071.22 CDJ65528.1 - 9.7e-50 168.3 3.2 3.9e-37 127.4 0.0 2.8 3 0 0 3 3 3 2 Ras family Roc PF08477.13 CDJ65528.1 - 1.2e-29 102.9 0.2 2.2e-17 63.4 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ65528.1 - 6.7e-14 51.7 4.8 3.8e-12 46.0 0.0 2.9 2 1 0 3 3 3 2 ADP-ribosylation factor family ABC_tran PF00005.27 CDJ65528.1 - 0.00099 19.6 5.0 0.0029 18.1 0.1 2.4 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 CDJ65528.1 - 0.0024 17.9 0.0 0.0095 16.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ65528.1 - 0.0044 16.9 5.5 0.019 14.9 0.0 3.1 2 1 1 3 3 3 1 RsgA GTPase AAA_7 PF12775.7 CDJ65528.1 - 0.0092 15.5 1.1 0.074 12.6 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_29 PF13555.6 CDJ65528.1 - 0.052 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 CDJ65528.1 - 0.059 12.6 0.2 0.059 12.6 0.2 2.2 2 0 0 2 2 2 0 Septin TFIIA PF03153.13 CDJ65528.1 - 0.13 12.3 40.8 0.53 10.2 9.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AAA_24 PF13479.6 CDJ65528.1 - 0.16 11.6 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CDJ65528.1 - 0.26 11.3 0.0 0.26 11.3 0.0 2.5 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) UPF1_Zn_bind PF09416.10 CDJ65528.1 - 3.1 7.8 10.9 0.19 11.7 5.4 1.7 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) AAA_22 PF13401.6 CDJ65528.1 - 4.4 7.6 12.9 0.11 12.8 0.6 3.0 2 2 0 2 2 2 0 AAA domain ANAPC_CDC26 PF10471.9 CDJ65530.1 - 0.02 15.7 19.0 0.02 15.7 19.0 3.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF2722 PF10846.8 CDJ65530.1 - 1.8 7.4 21.4 3 6.7 21.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Neur_chan_memb PF02932.16 CDJ65530.1 - 2.4 8.2 7.8 3.7 7.6 7.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SUIM_assoc PF16619.5 CDJ65531.1 - 0.014 15.5 11.7 0.014 15.5 11.7 7.7 5 2 2 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ65531.1 - 0.024 13.6 0.1 0.024 13.6 0.1 5.7 5 1 0 5 5 5 0 Protein of unknown function (DUF2722) HZS_alpha PF18582.1 CDJ65531.1 - 2.9 8.4 4.9 3.2 8.3 0.1 3.1 3 0 0 3 3 3 0 Hydrazine synthase alpha subunit middle domain SR-25 PF10500.9 CDJ65531.1 - 9.6 5.7 60.2 0.056 13.0 3.4 4.9 4 1 0 5 5 5 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ65532.1 - 0.045 13.4 20.1 0.06 13.0 20.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ65532.1 - 0.55 8.3 25.8 0.63 8.1 25.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IMUP PF15761.5 CDJ65532.1 - 2.4 8.9 15.1 4.9 7.9 15.1 1.7 1 1 0 1 1 1 0 Immortalisation up-regulated protein Chorion_2 PF03964.15 CDJ65532.1 - 4.2 8.3 15.9 8.4 7.3 15.9 1.6 1 1 0 1 1 1 0 Chorion family 2 RskA PF10099.9 CDJ65533.1 - 0.012 15.9 9.0 0.016 15.5 9.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Activator_LAG-3 PF11498.8 CDJ65533.1 - 0.51 9.2 16.2 0.6 9.0 16.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 MAP7 PF05672.11 CDJ65533.1 - 0.57 9.9 22.1 0.71 9.6 22.1 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF3280 PF11684.8 CDJ65533.1 - 0.58 10.6 7.3 0.76 10.2 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) TFIIA PF03153.13 CDJ65533.1 - 0.72 9.8 15.8 0.84 9.6 15.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAT1 PF06391.13 CDJ65533.1 - 2.7 7.8 15.4 3.7 7.3 15.4 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Presenilin PF01080.17 CDJ65533.1 - 3.4 6.4 5.8 3.6 6.3 5.8 1.1 1 0 0 1 1 1 0 Presenilin Exonuc_VII_L PF02601.15 CDJ65533.1 - 4.8 6.7 13.4 5.8 6.4 13.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DDHD PF02862.17 CDJ65533.1 - 5.2 7.2 7.5 6.2 6.9 7.5 1.1 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.6 CDJ65533.1 - 5.8 6.2 15.6 7.6 5.8 15.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Y_phosphatase3 PF13350.6 CDJ65534.1 - 0.014 15.4 4.5 0.014 15.4 4.5 2.1 2 1 0 2 2 2 0 Tyrosine phosphatase family SUIM_assoc PF16619.5 CDJ65534.1 - 0.025 14.7 0.2 0.025 14.7 0.2 3.7 3 1 1 4 4 2 0 Unstructured region C-term to UIM in Ataxin3 Cwf_Cwc_15 PF04889.12 CDJ65534.1 - 0.3 10.8 8.6 0.59 9.8 8.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2756 PF10956.8 CDJ65534.1 - 0.59 10.7 23.8 0.19 12.2 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) Med15 PF09606.10 CDJ65534.1 - 1.2 7.7 33.9 1.6 7.3 33.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.9 CDJ65534.1 - 1.3 7.2 18.1 1.6 6.9 18.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ65534.1 - 3.9 7.0 47.6 0.36 10.4 4.7 3.1 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 CDJ65534.1 - 3.9 5.9 21.6 0.64 8.5 15.8 2.1 2 0 0 2 2 2 0 Macoilin family Lin-8 PF03353.15 CDJ65534.1 - 4.9 6.6 20.3 0.23 11.0 13.8 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist eIF-3_zeta PF05091.12 CDJ65534.1 - 5.3 5.9 12.0 7.3 5.4 12.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ65534.1 - 6.6 5.6 10.0 9.3 5.1 10.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF508 PF04370.12 CDJ65534.1 - 7 6.4 12.9 7.8 6.2 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF508) TFIIA PF03153.13 CDJ65534.1 - 10 6.0 38.3 17 5.3 38.2 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MORN PF02493.20 CDJ65536.1 - 6.5e-20 69.8 10.4 2.6e-07 30.1 1.2 3.4 3 0 0 3 3 3 3 MORN repeat 2Fe-2S_Ferredox PF11591.8 CDJ65538.1 - 0.14 12.0 2.4 0.3 11.0 2.4 1.5 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide SnoaL_4 PF13577.6 CDJ65538.1 - 0.22 11.6 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Mito_carr PF00153.27 CDJ65539.1 - 2.7e-21 75.3 4.4 6.4e-17 61.3 0.0 2.6 3 0 0 3 3 3 2 Mitochondrial carrier protein RskA PF10099.9 CDJ65540.1 - 2.7e-05 24.6 12.9 2.7e-05 24.6 12.9 11.9 2 2 7 9 9 9 2 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ65540.1 - 0.0047 16.6 5.1 0.0047 16.6 5.1 8.6 3 1 5 9 9 9 2 Nuclear RNA-splicing-associated protein Helicase_C_3 PF13625.6 CDJ65541.1 - 1.9e-06 28.0 0.3 1.9e-06 28.0 0.3 2.5 1 1 1 2 2 2 1 Helicase conserved C-terminal domain Herpes_UL17 PF04559.12 CDJ65541.1 - 7 5.3 16.1 8.7 5.0 16.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL17 protein PHO4 PF01384.20 CDJ65542.1 - 8.8e-33 113.8 8.4 1.1e-32 113.4 8.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family RskA PF10099.9 CDJ65543.1 - 0.0066 16.8 12.4 0.0066 16.8 12.4 2.6 1 1 1 2 2 2 1 Anti-sigma-K factor rskA CDC27 PF09507.10 CDJ65543.1 - 0.83 9.0 45.3 0.98 8.7 45.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Trp_oprn_chp PF09534.10 CDJ65543.1 - 0.98 9.2 29.4 1.1 9.0 28.8 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Macoilin PF09726.9 CDJ65543.1 - 9.8 4.6 34.9 12 4.3 34.9 1.0 1 0 0 1 1 1 0 Macoilin family RhgB_N PF09284.10 CDJ65546.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Rhamnogalacturonan lyase B, N-terminal Ribosomal_L7Ae PF01248.26 CDJ65547.1 - 2e-19 69.1 0.0 4.5e-19 68.0 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RCC1 PF00415.18 CDJ65548.1 - 2e-30 105.1 16.5 1.7e-09 38.1 0.6 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ65548.1 - 4.4e-24 83.7 22.4 1.9e-09 37.1 1.1 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Fe-S_biosyn PF01521.20 CDJ65549.1 - 1.7e-08 34.6 0.2 1.8e-05 24.9 0.0 2.7 2 1 0 2 2 2 2 Iron-sulphur cluster biosynthesis DUF4667 PF15700.5 CDJ65549.1 - 0.0094 16.1 6.5 0.087 12.9 1.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ65549.1 - 0.086 12.4 0.2 0.086 12.4 0.2 3.0 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ65549.1 - 5.6 4.9 26.1 7.8 4.4 20.5 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Secretin_N_2 PF07655.13 CDJ65549.1 - 7.1 7.2 13.8 20 5.8 8.7 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4692 PF15763.5 CDJ65549.1 - 7.4 7.0 14.7 4.4 7.7 8.3 2.7 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Ndc1_Nup PF09531.10 CDJ65549.1 - 9.4 4.8 11.1 0.37 9.4 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup NDK PF00334.19 CDJ65550.1 - 5.6e-27 94.4 0.0 7.6e-26 90.7 0.0 2.1 2 0 0 2 2 2 1 Nucleoside diphosphate kinase DUF1126 PF06565.12 CDJ65550.1 - 3.7e-06 26.7 0.0 6.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 DUF1126 PH-like domain AAA_5 PF07728.14 CDJ65551.1 - 1.4e-103 342.5 0.0 8.9e-21 74.3 0.0 10.2 9 1 0 9 9 9 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CDJ65551.1 - 3.8e-28 97.8 8.8 5.3e-13 49.1 0.6 5.9 5 0 0 5 5 5 2 Midasin AAA lid domain AAA_lid_5 PF17865.1 CDJ65551.1 - 2.7e-21 75.6 0.1 9.9e-21 73.8 0.0 2.1 2 0 0 2 2 1 1 Midasin AAA lid domain AAA PF00004.29 CDJ65551.1 - 9e-21 74.7 0.0 0.0043 17.5 0.0 7.1 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 CDJ65551.1 - 5.1e-20 71.7 0.0 0.00022 21.1 0.0 7.7 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 CDJ65551.1 - 6.4e-16 58.5 0.1 8.8e-06 25.8 0.0 6.0 5 0 0 5 5 5 3 Dynein heavy chain region D6 P-loop domain TsaE PF02367.17 CDJ65551.1 - 9.6e-13 48.2 2.0 0.074 13.0 0.3 6.4 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CDJ65551.1 - 6.6e-12 45.8 15.0 6.6e-05 23.1 0.0 7.6 6 0 0 6 6 4 3 AAA domain AAA_22 PF13401.6 CDJ65551.1 - 1.6e-11 44.6 18.4 0.035 14.4 0.0 9.6 9 0 0 9 9 7 3 AAA domain AAA_7 PF12775.7 CDJ65551.1 - 2.6e-11 43.3 0.0 0.25 10.8 0.0 6.4 6 0 0 6 6 6 2 P-loop containing dynein motor region AAA_18 PF13238.6 CDJ65551.1 - 6.6e-09 36.4 0.0 0.59 10.7 0.0 7.2 6 0 0 6 6 6 1 AAA domain Mg_chelatase PF01078.21 CDJ65551.1 - 2.5e-08 33.6 2.7 0.11 11.9 0.1 7.1 7 0 0 7 7 7 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CDJ65551.1 - 9.4e-08 32.1 5.1 1.1 9.2 0.0 7.0 6 0 0 6 6 6 2 NACHT domain Sigma54_activ_2 PF14532.6 CDJ65551.1 - 1.8e-06 28.1 4.1 1.1 9.4 0.0 6.9 6 0 0 6 6 5 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 CDJ65551.1 - 8.8e-06 25.5 3.5 4.6 6.9 0.0 6.3 7 0 0 7 7 7 1 Sigma-54 interaction domain ABC_tran PF00005.27 CDJ65551.1 - 1.2e-05 25.8 8.6 3.7 8.1 0.0 7.9 7 0 0 7 7 6 1 ABC transporter DUF815 PF05673.13 CDJ65551.1 - 5.1e-05 22.5 4.6 0.087 12.0 0.0 5.5 6 0 0 6 6 6 1 Protein of unknown function (DUF815) AAA_8 PF12780.7 CDJ65551.1 - 9.4e-05 21.9 0.0 0.06 12.7 0.0 4.4 5 0 0 5 5 5 1 P-loop containing dynein motor region D4 AAA_14 PF13173.6 CDJ65551.1 - 0.00018 21.5 0.0 0.23 11.5 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 CDJ65551.1 - 0.0003 21.2 1.5 0.0056 17.1 0.3 17.6 13 4 3 16 16 10 6 AAA ATPase domain RNA_helicase PF00910.22 CDJ65551.1 - 0.0003 21.1 0.0 89 3.5 0.0 6.0 6 0 0 6 6 6 0 RNA helicase AAA_29 PF13555.6 CDJ65551.1 - 0.00034 20.3 4.2 29 4.5 0.0 6.7 7 0 0 7 7 7 0 P-loop containing region of AAA domain RuvB_N PF05496.12 CDJ65551.1 - 0.0012 18.6 0.3 27 4.4 0.0 6.1 7 0 0 7 7 7 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CDJ65551.1 - 0.002 18.1 0.8 4.7 7.1 0.0 4.6 6 0 0 6 6 4 1 Rad17 P-loop domain AAA_6 PF12774.7 CDJ65551.1 - 0.0087 15.1 4.8 2.4 7.0 0.0 4.7 5 0 0 5 5 4 1 Hydrolytic ATP binding site of dynein motor region DEAD PF00270.29 CDJ65551.1 - 0.023 14.5 0.4 21 4.8 0.1 3.9 4 0 0 4 4 4 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 CDJ65551.1 - 0.048 13.4 0.0 2.3 7.9 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase dNK PF01712.19 CDJ65551.1 - 0.074 12.9 0.1 2.5 7.9 0.0 3.1 3 0 0 3 3 3 0 Deoxynucleoside kinase Roc PF08477.13 CDJ65551.1 - 0.18 12.0 0.5 76 3.5 0.0 4.0 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 CDJ65551.1 - 7.9 6.9 0.0 4.3 7.8 0.0 13.8 13 3 0 13 13 7 0 AAA domain DUF755 PF05501.11 CDJ65552.1 - 0.00062 20.0 16.1 0.00062 20.0 16.1 13.5 14 1 0 14 14 14 1 Domain of unknown function (DUF755) GTP_EFTU PF00009.27 CDJ65554.1 - 5.1e-21 75.1 0.0 3.8e-20 72.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ65554.1 - 5e-05 23.3 0.0 0.00023 21.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDJ65554.1 - 0.26 11.3 0.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.20 CDJ65554.1 - 0.3 10.2 0.0 0.44 9.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit TFIIA PF03153.13 CDJ65554.1 - 1.7 8.6 18.6 5 7.0 18.6 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CDJ65555.1 - 1.2e-49 169.0 0.0 2.4e-49 168.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65555.1 - 5.2e-24 84.9 0.0 1.1e-16 60.9 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ65555.1 - 8.6e-05 21.5 0.0 8.6e-05 21.5 0.0 2.7 2 1 0 2 2 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ65555.1 - 0.00016 21.1 2.8 0.013 14.8 0.0 2.7 3 0 0 3 3 3 2 Kinase-like RIO1 PF01163.22 CDJ65555.1 - 0.00084 19.0 0.1 0.0022 17.6 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CDJ65555.1 - 0.011 15.7 0.0 0.031 14.2 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Macoilin PF09726.9 CDJ65555.1 - 0.021 13.4 20.7 0.028 13.0 20.7 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 CDJ65555.1 - 0.025 14.5 19.2 0.036 14.0 19.2 1.2 1 0 0 1 1 1 0 SPX domain Kdo PF06293.14 CDJ65555.1 - 0.046 13.1 0.1 0.084 12.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CDJ65555.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Apt1 PF10351.9 CDJ65555.1 - 0.15 10.9 19.6 0.25 10.2 19.6 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain V_ATPase_I PF01496.19 CDJ65555.1 - 0.24 9.3 6.9 0.33 8.8 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GREB1 PF15782.5 CDJ65555.1 - 1 6.4 21.9 1.3 6.0 21.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF966 PF06136.13 CDJ65555.1 - 1.2 8.8 22.9 1.8 8.2 22.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAPS PF04499.15 CDJ65555.1 - 5.8 5.6 13.6 9 5.0 13.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lin-8 PF03353.15 CDJ65555.1 - 8.2 5.9 24.9 13 5.3 24.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RR_TM4-6 PF06459.12 CDJ65555.1 - 9.4 6.0 19.3 17 5.1 19.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2722 PF10846.8 CDJ65556.1 - 0.0015 17.6 6.2 0.0015 17.6 6.2 7.2 6 2 1 7 7 7 2 Protein of unknown function (DUF2722) DUF1645 PF07816.11 CDJ65556.1 - 0.013 16.1 0.5 0.013 16.1 0.5 6.6 6 1 0 6 6 6 0 Protein of unknown function (DUF1645) TMEM51 PF15345.6 CDJ65560.1 - 0.002 18.1 0.6 0.002 18.1 0.6 4.4 4 2 2 6 6 6 2 Transmembrane protein 51 BatD PF13584.6 CDJ65560.1 - 4.8 5.9 17.9 5.5 5.7 0.3 3.3 2 1 2 4 4 4 0 Oxygen tolerance Peptidase_M56 PF05569.11 CDJ65560.1 - 5.3 6.1 8.2 2.2 7.4 3.9 2.2 1 1 1 2 2 2 0 BlaR1 peptidase M56 Amnionless PF14828.6 CDJ65560.1 - 5.8 5.6 13.7 0.64 8.8 2.5 2.7 3 0 0 3 3 3 0 Amnionless Ribosomal_60s PF00428.19 CDJ65561.1 - 3.7e-05 24.2 1.2 3.7e-05 24.2 1.2 4.2 3 1 0 3 3 3 1 60s Acidic ribosomal protein Xpo1 PF08389.12 CDJ65561.1 - 0.0044 17.1 3.5 0.01 15.9 3.5 1.7 1 1 0 1 1 1 1 Exportin 1-like protein Activator_LAG-3 PF11498.8 CDJ65561.1 - 2.4 7.0 26.8 3.6 6.4 26.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SUIM_assoc PF16619.5 CDJ65563.1 - 0.066 13.3 0.0 0.066 13.3 0.0 6.2 3 3 2 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 DUF3399 PF11879.8 CDJ65564.1 - 2.4 8.5 6.2 5.3 7.4 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) RskA PF10099.9 CDJ65565.1 - 0.0029 17.9 4.6 0.0029 17.9 4.6 3.5 2 1 0 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ65565.1 - 4.3 7.2 9.6 5.8 6.8 9.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ65566.1 - 1.5e-05 25.4 29.1 0.0084 16.4 20.5 2.3 2 0 0 2 2 2 2 Anti-sigma-K factor rskA SARAF PF06682.12 CDJ65566.1 - 0.0022 17.7 12.3 0.0032 17.2 12.3 1.3 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis FHIPEP PF00771.20 CDJ65566.1 - 0.0089 14.6 10.4 0.01 14.4 10.4 1.1 1 0 0 1 1 1 1 FHIPEP family SID-1_RNA_chan PF13965.6 CDJ65566.1 - 0.017 13.6 4.2 0.023 13.1 4.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 CDJ65566.1 - 0.048 14.6 0.2 0.048 14.6 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) ANAPC_CDC26 PF10471.9 CDJ65566.1 - 0.051 14.4 5.1 0.051 14.4 5.1 4.0 2 1 1 3 3 1 0 Anaphase-promoting complex APC subunit CDC26 Shadoo PF14999.6 CDJ65566.1 - 0.061 13.4 0.1 0.061 13.4 0.1 2.0 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective FAM176 PF14851.6 CDJ65566.1 - 0.072 12.8 11.2 4.1 7.1 0.0 3.2 3 0 0 3 3 3 0 FAM176 family CTU2 PF10288.9 CDJ65566.1 - 0.11 12.8 0.5 0.11 12.8 0.5 3.2 2 1 0 2 2 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF3357 PF11837.8 CDJ65566.1 - 0.25 11.8 8.8 5.1 7.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Fer4_10 PF13237.6 CDJ65566.1 - 0.83 9.8 4.1 2.9 8.1 0.5 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zip PF02535.22 CDJ65566.1 - 7.6 5.6 15.7 1.7 7.8 6.4 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter RskA PF10099.9 CDJ65567.1 - 4.1e-08 33.7 1.5 4.1e-08 33.7 1.5 5.5 1 1 2 3 3 3 1 Anti-sigma-K factor rskA SNF2_N PF00176.23 CDJ65568.1 - 9e-18 64.1 0.0 9e-18 64.1 0.0 1.7 3 0 0 3 3 3 1 SNF2 family N-terminal domain DUF2722 PF10846.8 CDJ65568.1 - 4e-05 22.8 5.2 4e-05 22.8 5.2 3.6 2 1 1 4 4 4 1 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ65568.1 - 0.0035 17.4 8.5 0.0035 17.4 8.5 5.0 4 2 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 CDJ65568.1 - 0.0043 17.8 10.7 0.0043 17.8 10.7 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex APC subunit CDC26 Ribosomal_L4 PF00573.22 CDJ65570.1 - 1.5e-15 57.4 5.1 5.2e-08 32.8 2.7 2.3 1 1 1 2 2 2 2 Ribosomal protein L4/L1 family ELO PF01151.18 CDJ65571.1 - 2.3e-63 214.0 22.0 2.8e-63 213.8 22.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Activator_LAG-3 PF11498.8 CDJ65573.1 - 0.00075 18.6 26.1 0.00075 18.6 26.1 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 EIF4E-T PF10477.9 CDJ65573.1 - 0.12 11.2 13.0 0.11 11.3 13.0 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF702 PF05142.12 CDJ65573.1 - 0.68 10.4 5.2 0.92 10.0 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) TFIIA PF03153.13 CDJ65573.1 - 2.2 8.2 21.0 2.2 8.2 21.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lactamase_B_2 PF12706.7 CDJ65574.1 - 1.6e-05 24.6 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ65574.1 - 0.026 14.5 0.9 0.05 13.6 0.9 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DivIC PF04977.15 CDJ65574.1 - 0.55 10.0 10.0 0.94 9.3 10.0 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4834 PF16118.5 CDJ65574.1 - 3 8.9 5.9 4.6 8.3 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ65574.1 - 4.2 6.0 4.4 5.5 5.7 4.4 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ65574.1 - 5.9 6.4 20.9 8.4 5.9 20.9 1.2 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ65575.1 - 0.0015 18.8 24.8 0.002 18.5 24.8 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TraT PF05818.12 CDJ65575.1 - 0.0018 18.0 4.0 0.0027 17.4 4.0 1.3 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein FPN1 PF06963.12 CDJ65575.1 - 0.0034 16.0 0.6 0.0036 15.9 0.6 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MAS20 PF02064.15 CDJ65575.1 - 0.024 14.7 8.1 0.024 14.7 8.1 2.1 1 1 1 2 2 2 0 MAS20 protein import receptor FHIPEP PF00771.20 CDJ65575.1 - 0.047 12.2 6.3 0.054 12.0 6.3 1.0 1 0 0 1 1 1 0 FHIPEP family DcuC PF03606.15 CDJ65575.1 - 0.054 11.9 1.9 0.062 11.7 1.9 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier NEMP PF10225.9 CDJ65575.1 - 0.22 11.2 2.8 0.22 11.2 2.8 1.2 1 0 0 1 1 1 0 NEMP family eIF-3_zeta PF05091.12 CDJ65575.1 - 0.23 10.4 10.3 0.26 10.2 10.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BAF1_ABF1 PF04684.13 CDJ65575.1 - 0.23 10.5 11.6 0.33 9.9 11.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SID-1_RNA_chan PF13965.6 CDJ65575.1 - 0.3 9.5 2.0 0.33 9.3 2.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIA PF03153.13 CDJ65575.1 - 0.32 10.9 30.9 0.36 10.8 30.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2681 PF10883.8 CDJ65575.1 - 0.44 11.0 22.5 0.19 12.2 16.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) R_equi_Vir PF05526.11 CDJ65575.1 - 0.67 9.8 8.6 0.86 9.4 8.6 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Presenilin PF01080.17 CDJ65575.1 - 1.1 7.9 11.2 1.3 7.7 11.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ65575.1 - 1.3 10.1 12.9 0.26 12.3 7.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ65575.1 - 1.9 8.4 16.0 2.3 8.2 16.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM199X PF15814.5 CDJ65575.1 - 2.1 7.3 12.1 2.5 7.1 12.1 1.1 1 0 0 1 1 1 0 Protein family FAM199X MIIP PF15734.5 CDJ65575.1 - 3.3 7.1 15.0 3.7 6.9 15.0 1.0 1 0 0 1 1 1 0 Migration and invasion-inhibitory THOC2_N PF16134.5 CDJ65575.1 - 3.7 6.1 10.6 4.3 5.9 10.6 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF3533 PF12051.8 CDJ65575.1 - 4.1 6.2 5.8 4.2 6.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Neur_chan_memb PF02932.16 CDJ65575.1 - 5.3 7.0 9.0 6.5 6.7 9.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF5327 PF17261.2 CDJ65575.1 - 5.4 7.8 19.8 1 10.1 15.8 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5327) IMUP PF15761.5 CDJ65577.1 - 0.25 12.1 7.4 0.73 10.5 7.4 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ65577.1 - 0.31 10.6 10.8 0.58 9.7 10.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3597 PF12200.8 CDJ65577.1 - 1.5 9.4 6.3 2.1 8.9 4.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Sporozoite_P67 PF05642.11 CDJ65578.1 - 2.3 6.2 17.0 2.8 5.9 17.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mg_trans_NIPA PF05653.14 CDJ65581.1 - 5.1e-13 48.8 9.9 2.8e-08 33.2 0.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Pex2_Pex12 PF04757.14 CDJ65582.1 - 1.4e-20 73.9 7.2 2.8e-20 72.9 7.2 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 CDJ65582.1 - 0.074 13.0 5.7 0.14 12.1 5.2 1.8 1 1 0 1 1 1 0 zinc-RING finger domain Connexin PF00029.19 CDJ65582.1 - 0.13 12.0 5.0 0.056 13.2 0.9 2.1 2 0 0 2 2 2 0 Connexin zf-HC5HC2H PF13771.6 CDJ65582.1 - 0.14 12.4 2.3 0.48 10.7 2.3 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_3 PF13920.6 CDJ65582.1 - 0.28 11.1 9.1 0.89 9.5 9.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CAF1 PF04857.20 CDJ65582.1 - 1.1 8.4 3.5 1.4 8.0 0.3 2.2 2 0 0 2 2 2 0 CAF1 family ribonuclease RuvX PF03652.15 CDJ65583.1 - 3.2e-13 50.2 1.2 1.3e-08 35.4 0.0 2.7 3 0 0 3 3 3 2 Holliday junction resolvase TFB6 PF17110.5 CDJ65583.1 - 0.22 11.3 2.6 0.38 10.5 2.6 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH BORG_CEP PF14957.6 CDJ65583.1 - 0.93 10.7 8.1 0.11 13.7 2.8 2.1 2 1 0 2 2 2 0 Cdc42 effector IKBKB_SDD PF18397.1 CDJ65584.1 - 0.039 13.3 3.2 0.08 12.2 3.2 1.4 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain Methyltr_RsmB-F PF01189.17 CDJ65585.1 - 3e-11 43.3 0.9 2e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F TFIIA PF03153.13 CDJ65586.1 - 0.0017 18.5 25.5 0.0022 18.1 4.3 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Pox_F17 PF04767.12 CDJ65586.1 - 0.01 16.3 1.2 0.053 14.0 1.2 2.3 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein Ribosomal_60s PF00428.19 CDJ65586.1 - 0.016 15.8 6.1 0.016 15.8 6.1 5.3 5 1 0 5 5 5 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ65586.1 - 0.06 13.0 22.1 0.019 14.6 4.8 2.2 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ65586.1 - 0.34 10.5 24.0 1.2 8.7 8.8 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ65586.1 - 0.46 9.4 16.4 0.034 13.1 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SPX PF03105.19 CDJ65586.1 - 4.6 7.1 11.9 0.23 11.3 4.5 2.0 2 0 0 2 2 2 0 SPX domain DUF3446 PF11928.8 CDJ65586.1 - 5.2 7.4 40.0 0.25 11.7 8.9 4.6 4 0 0 4 4 4 0 Early growth response N-terminal domain CCDC84 PF14968.6 CDJ65587.1 - 0.036 13.7 0.3 0.036 13.7 0.3 2.2 1 1 0 2 2 2 0 Coiled coil protein 84 SpoIIP PF07454.11 CDJ65587.1 - 1.2 8.6 23.4 0.43 10.0 0.5 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) GREB1 PF15782.5 CDJ65588.1 - 0.015 12.5 4.6 0.019 12.2 4.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Membralin PF09746.9 CDJ65588.1 - 0.038 13.0 0.0 0.038 13.0 0.0 1.7 2 0 0 2 2 2 0 Tumour-associated protein Spt20 PF12090.8 CDJ65588.1 - 0.089 12.4 6.2 0.13 11.9 6.2 1.2 1 0 0 1 1 1 0 Spt20 family Ank_3 PF13606.6 CDJ65588.1 - 0.43 11.3 0.2 0.43 11.3 0.2 3.2 2 0 0 2 2 2 0 Ankyrin repeat DUF1712 PF08217.11 CDJ65588.1 - 0.46 8.9 3.9 0.6 8.5 3.9 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) ALMT PF11744.8 CDJ65588.1 - 1.1 8.0 6.0 1.5 7.5 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SPX PF03105.19 CDJ65588.1 - 3.3 7.5 12.7 4.4 7.1 12.7 1.0 1 0 0 1 1 1 0 SPX domain Sporozoite_P67 PF05642.11 CDJ65588.1 - 3.6 5.5 8.8 4.6 5.2 8.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Rad60-SLD_2 PF13881.6 CDJ65589.1 - 0.00016 21.7 0.0 0.00021 21.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDJ65589.1 - 0.052 13.3 0.0 0.21 11.4 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin family DUF5067 PF16729.5 CDJ65589.1 - 0.077 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) Ldh_1_C PF02866.18 CDJ65590.1 - 4.5e-20 72.2 0.0 5.3e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4C PF11975.8 CDJ65590.1 - 0.061 13.4 0.1 0.094 12.8 0.1 1.5 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Mito_carr PF00153.27 CDJ65590.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein SepF PF04472.12 CDJ65590.1 - 0.16 12.3 0.0 15 6.0 0.0 2.3 2 0 0 2 2 2 0 Cell division protein SepF HD_5 PF13487.6 CDJ65590.1 - 0.19 12.0 0.2 0.47 10.7 0.1 1.7 2 0 0 2 2 2 0 HD domain Peptidase_U4 PF03419.13 CDJ65591.1 - 0.53 9.5 1.4 0.61 9.3 1.4 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA SRP-alpha_N PF04086.13 CDJ65591.1 - 0.56 10.1 17.9 0.67 9.8 17.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CSG2 PF16965.5 CDJ65591.1 - 1.8 7.4 13.6 2 7.3 13.6 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Myc_N PF01056.18 CDJ65591.1 - 2.5 7.9 15.3 2.9 7.7 15.3 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Presenilin PF01080.17 CDJ65591.1 - 2.5 6.8 19.9 3.4 6.3 19.9 1.2 1 0 0 1 1 1 0 Presenilin K_trans PF02705.16 CDJ65591.1 - 8.2 4.8 6.7 9.1 4.6 6.7 1.0 1 0 0 1 1 1 0 K+ potassium transporter Rib_recp_KP_reg PF05104.12 CDJ65592.1 - 0.062 14.3 26.9 0.076 14.1 26.9 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region DUF4698 PF15769.5 CDJ65592.1 - 0.065 12.3 6.4 0.072 12.1 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) AF-4 PF05110.13 CDJ65592.1 - 0.13 10.3 20.7 0.13 10.4 20.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SPX PF03105.19 CDJ65592.1 - 0.8 9.5 19.8 0.86 9.4 19.8 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ65592.1 - 1 8.1 19.1 1 8.2 19.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Miga PF10265.9 CDJ65592.1 - 1.2 8.1 19.9 1.3 8.0 19.9 1.1 1 0 0 1 1 1 0 Mitoguardin MPM1 PF17234.2 CDJ65592.1 - 1.8 8.8 14.5 2.2 8.5 14.5 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 SKA1 PF07160.12 CDJ65592.1 - 2.1 8.1 12.7 2.2 8.0 12.7 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Draxin PF15550.6 CDJ65592.1 - 2.1 8.1 13.4 2.6 7.8 13.4 1.3 1 0 0 1 1 1 0 Draxin FAM60A PF15396.6 CDJ65592.1 - 2.1 8.3 10.1 2.3 8.2 10.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A LST1 PF05083.13 CDJ65592.1 - 3 8.2 4.2 4.1 7.8 4.2 1.3 1 0 0 1 1 1 0 LST-1 protein DUF1387 PF07139.11 CDJ65592.1 - 3.5 7.3 16.2 3.9 7.1 16.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CSRNP_N PF16019.5 CDJ65592.1 - 3.8 7.4 9.8 4.4 7.2 9.8 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Plasmodium_Vir PF05795.11 CDJ65592.1 - 4.2 6.7 13.9 4.7 6.5 13.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM76 PF16046.5 CDJ65592.1 - 4.6 6.5 15.6 5.2 6.3 15.6 1.1 1 0 0 1 1 1 0 FAM76 protein NST1 PF13945.6 CDJ65592.1 - 5.2 7.1 32.7 4.9 7.2 31.6 1.4 1 1 1 2 2 2 0 Salt tolerance down-regulator NPR3 PF03666.13 CDJ65592.1 - 7.1 5.3 17.5 7.4 5.2 17.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Lin-8 PF03353.15 CDJ65592.1 - 9.3 5.7 22.0 11 5.5 22.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2722 PF10846.8 CDJ65593.1 - 3.9e-05 22.8 3.2 4.4e-05 22.6 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ65593.1 - 0.0026 18.1 0.4 1.5 9.1 0.0 2.1 2 0 0 2 2 2 2 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ65593.1 - 0.012 15.7 9.1 0.014 15.4 9.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ65593.1 - 0.025 13.3 13.2 0.031 13.0 13.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FHIPEP PF00771.20 CDJ65593.1 - 0.037 12.5 0.0 0.048 12.1 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family TssO PF17561.2 CDJ65593.1 - 0.19 11.8 0.2 0.19 11.8 0.2 3.0 3 0 0 3 3 3 0 Type VI secretion system, TssO DUF4407 PF14362.6 CDJ65593.1 - 0.4 10.0 2.5 1 8.6 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Suf PF05843.14 CDJ65593.1 - 0.61 10.0 4.9 0.82 9.6 4.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) O-ag_pol_Wzy PF14296.6 CDJ65593.1 - 1.6 7.3 14.2 2.5 6.6 14.2 1.2 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy Spt20 PF12090.8 CDJ65593.1 - 1.7 8.2 21.8 2.5 7.7 21.8 1.2 1 0 0 1 1 1 0 Spt20 family DUF5349 PF17298.2 CDJ65593.1 - 5.7 6.6 9.0 8 6.1 9.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF4834 PF16118.5 CDJ65593.1 - 5.9 7.9 11.3 2.9 8.9 6.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TMEM51 PF15345.6 CDJ65593.1 - 7.8 6.3 7.7 12 5.7 7.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Pyr_redox_2 PF07992.14 CDJ65594.1 - 1.5e-21 76.9 0.0 1.6e-18 67.0 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ65594.1 - 6.8e-19 68.2 0.0 1.7e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ65594.1 - 2.4e-13 50.5 0.0 4.3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF2722 PF10846.8 CDJ65594.1 - 0.00018 20.6 3.5 0.00018 20.6 3.5 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF2722) 2-Hacid_dh_C PF02826.19 CDJ65594.1 - 0.0049 16.3 0.0 0.0049 16.3 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CDJ65594.1 - 0.028 14.0 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 CDJ65594.1 - 0.054 13.4 1.4 0.059 13.3 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 CDJ65594.1 - 0.35 11.1 3.4 0.57 10.5 0.3 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SR-25 PF10500.9 CDJ65594.1 - 1.2 8.7 40.3 0.054 13.1 8.0 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein KH_1 PF00013.29 CDJ65595.1 - 2e-07 30.7 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 KH domain WD40 PF00400.32 CDJ65596.1 - 0.058 14.3 2.9 9.9 7.2 0.0 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF4171 PF13775.6 CDJ65596.1 - 1.3 9.5 11.2 0.17 12.3 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4171) FAD_binding_3 PF01494.19 CDJ65598.1 - 3.9e-13 49.4 0.1 5e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CDJ65598.1 - 0.00032 20.4 0.3 0.00054 19.6 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Macoilin PF09726.9 CDJ65598.1 - 0.00091 17.9 12.9 0.00095 17.9 12.9 1.0 1 0 0 1 1 1 1 Macoilin family NAD_binding_8 PF13450.6 CDJ65598.1 - 0.0011 19.2 0.2 0.0023 18.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CDJ65598.1 - 0.0013 18.0 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Alpha_GJ PF03229.13 CDJ65598.1 - 0.0033 18.0 2.4 0.0051 17.4 2.4 1.2 1 0 0 1 1 1 1 Alphavirus glycoprotein J Apt1 PF10351.9 CDJ65598.1 - 0.016 14.1 10.9 0.018 14.0 10.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pyr_redox_2 PF07992.14 CDJ65598.1 - 0.045 13.0 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ65598.1 - 0.11 11.6 0.2 0.14 11.2 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain QWRF PF04484.12 CDJ65598.1 - 0.12 12.1 11.3 0.13 12.0 11.3 1.1 1 0 0 1 1 1 0 QWRF family Thi4 PF01946.17 CDJ65598.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Thi4 family Zip PF02535.22 CDJ65598.1 - 0.15 11.3 1.4 0.18 11.0 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SPX PF03105.19 CDJ65598.1 - 0.23 11.4 13.9 0.25 11.2 13.9 1.0 1 0 0 1 1 1 0 SPX domain Atrophin-1 PF03154.15 CDJ65598.1 - 0.68 8.1 12.5 0.74 8.0 12.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family Tmemb_cc2 PF10267.9 CDJ65598.1 - 0.79 8.8 6.4 0.87 8.7 6.4 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MMU163 PF17119.5 CDJ65598.1 - 1.3 8.1 5.3 1.8 7.6 5.3 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Menin PF05053.13 CDJ65598.1 - 3.8 5.8 15.8 4.7 5.4 15.8 1.0 1 0 0 1 1 1 0 Menin Peptidase_S64 PF08192.11 CDJ65598.1 - 5 5.5 12.4 6 5.2 12.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 CDJ65598.1 - 6.7 3.7 11.3 8.4 3.4 11.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ribosomal_L12 PF00542.19 CDJ65599.1 - 6.5e-18 64.8 3.2 1e-17 64.3 1.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CDJ65599.1 - 3.8e-12 45.7 17.7 3.8e-12 45.7 17.7 4.5 3 2 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Spt20 PF12090.8 CDJ65600.1 - 0.011 15.4 6.1 0.011 15.4 6.1 6.3 3 2 2 5 5 5 0 Spt20 family TFIIF_alpha PF05793.12 CDJ65600.1 - 7.7 5.0 41.8 0.039 12.6 31.9 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4614 PF15391.6 CDJ65601.1 - 0.15 12.0 11.0 0.17 11.9 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF1635 PF07795.11 CDJ65601.1 - 0.17 11.7 5.1 0.2 11.5 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Spt20 PF12090.8 CDJ65601.1 - 1.5 8.3 12.5 1.8 8.1 12.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF1631 PF07793.11 CDJ65601.1 - 3.3 6.0 21.5 3.2 6.0 21.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Neur_chan_memb PF02932.16 CDJ65601.1 - 10 6.1 6.8 11 6.0 6.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDP-OH_P_transf PF01066.21 CDJ65602.1 - 9.3e-13 48.7 0.2 9.3e-13 48.7 0.2 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SPX PF03105.19 CDJ65602.1 - 0.0086 16.0 15.0 0.014 15.3 15.0 1.3 1 0 0 1 1 1 1 SPX domain Sporozoite_P67 PF05642.11 CDJ65603.1 - 0.44 8.6 19.8 0.72 7.9 19.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BCAS2 PF05700.11 CDJ65604.1 - 0.032 13.9 0.1 0.048 13.4 0.1 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) AAA_2 PF07724.14 CDJ65605.1 - 6.1e-23 81.8 0.1 4.3e-22 79.0 0.0 2.4 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CDJ65605.1 - 5.7e-21 74.4 2.5 5.7e-21 74.4 2.5 1.8 2 0 0 2 2 1 1 AAA lid domain AAA PF00004.29 CDJ65605.1 - 1.1e-14 55.0 0.0 1.4e-06 28.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ65605.1 - 3.1e-07 30.3 0.7 0.01 15.6 0.0 2.7 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ65605.1 - 8.5e-06 26.3 3.4 0.0042 17.5 0.0 3.4 3 1 1 4 4 3 2 AAA ATPase domain Zeta_toxin PF06414.12 CDJ65605.1 - 3.6e-05 23.1 0.1 0.00061 19.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin TniB PF05621.11 CDJ65605.1 - 3.8e-05 23.2 0.1 0.005 16.3 0.0 2.7 3 0 0 3 3 2 1 Bacterial TniB protein Sigma54_activat PF00158.26 CDJ65605.1 - 5.4e-05 23.0 0.0 0.00048 19.9 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 CDJ65605.1 - 9.6e-05 22.4 0.3 0.0026 17.7 0.0 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CDJ65605.1 - 0.00011 22.2 0.7 0.8 9.6 0.0 3.2 3 1 0 3 3 3 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CDJ65605.1 - 0.00066 19.7 0.0 0.5 10.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CDJ65605.1 - 0.0045 17.3 3.9 3 8.1 0.1 4.0 2 2 1 3 3 3 1 AAA domain AAA_18 PF13238.6 CDJ65605.1 - 0.0085 16.6 0.2 0.081 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDJ65605.1 - 0.01 15.4 0.0 0.58 9.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region SUIM_assoc PF16619.5 CDJ65605.1 - 0.018 15.1 0.7 0.018 15.1 0.7 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF815 PF05673.13 CDJ65605.1 - 0.028 13.6 0.3 0.43 9.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 CDJ65605.1 - 0.032 14.4 0.0 0.089 13.0 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CDJ65605.1 - 0.039 13.8 0.1 0.1 12.5 0.1 1.7 1 1 0 1 1 1 0 RsgA GTPase Torsin PF06309.11 CDJ65605.1 - 0.042 14.0 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 1 0 Torsin Bac_DnaA PF00308.18 CDJ65605.1 - 0.043 13.6 0.5 0.53 10.1 0.0 2.6 3 1 0 3 3 3 0 Bacterial dnaA protein IstB_IS21 PF01695.17 CDJ65605.1 - 0.043 13.5 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein TFIIA PF03153.13 CDJ65605.1 - 0.057 13.4 5.8 0.068 13.2 5.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ArsA_ATPase PF02374.15 CDJ65605.1 - 0.17 11.0 3.8 3.6 6.7 0.0 3.4 4 0 0 4 4 4 0 Anion-transporting ATPase PAP_central PF04928.17 CDJ65605.1 - 0.18 10.8 5.9 3.1 6.7 1.2 2.2 1 1 1 2 2 2 0 Poly(A) polymerase central domain AAA_33 PF13671.6 CDJ65605.1 - 0.22 11.7 2.0 1.4 9.1 0.0 3.1 3 1 0 3 3 2 0 AAA domain DUF87 PF01935.17 CDJ65605.1 - 0.24 11.5 1.3 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 CDJ65605.1 - 0.35 11.4 11.5 0.56 10.7 7.2 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CDJ65605.1 - 0.39 11.2 4.1 0.64 10.5 0.0 2.7 1 1 1 2 2 2 0 ABC transporter DUF1690 PF07956.11 CDJ65605.1 - 1.6 9.1 10.3 3.1 8.2 10.3 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) ClpB_D2-small PF10431.9 CDJ65606.1 - 1.3e-13 50.8 0.0 2.3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_2 PF07724.14 CDJ65606.1 - 3.6e-09 37.0 0.0 6.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) LRR_10 PF18805.1 CDJ65607.1 - 0.013 15.1 0.1 0.031 13.9 0.0 1.6 2 0 0 2 2 2 0 Leucine-rich repeat Ins145_P3_rec PF08709.11 CDJ65607.1 - 0.078 12.2 0.0 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Aminotran_5 PF00266.19 CDJ65609.1 - 3.7e-27 95.2 0.0 1.7e-26 93.1 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V HHH_6 PF14579.6 CDJ65609.1 - 0.0027 17.9 0.1 2.5 8.4 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif Prok-RING_1 PF14446.6 CDJ65610.1 - 0.00055 19.8 0.4 0.00055 19.8 0.4 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD PF00628.29 CDJ65610.1 - 0.02 14.8 1.4 0.02 14.8 1.4 3.7 3 0 0 3 3 3 0 PHD-finger FYDLN_acid PF09538.10 CDJ65610.1 - 8.9 7.1 10.9 0.65 10.7 2.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF4366 PF14283.6 CDJ65611.1 - 0.089 12.8 2.2 0.32 11.0 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Syja_N PF02383.18 CDJ65612.1 - 5.5e-43 147.5 0.0 5.4e-41 140.9 0.0 3.2 3 1 0 3 3 3 1 SacI homology domain DUF2845 PF11006.8 CDJ65612.1 - 0.08 13.0 0.1 0.08 13.0 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2845) PX PF00787.24 CDJ65613.1 - 9.5e-15 54.6 0.0 2.3e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 PX domain SUIM_assoc PF16619.5 CDJ65613.1 - 0.0033 17.4 0.0 0.0033 17.4 0.0 11.8 9 4 0 9 9 9 2 Unstructured region C-term to UIM in Ataxin3 Ras PF00071.22 CDJ65614.1 - 2.8e-14 53.1 0.0 7.1e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CDJ65614.1 - 1.5e-07 31.7 0.0 4.3e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 CDJ65614.1 - 0.027 14.6 0.4 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CDJ65614.1 - 0.037 14.1 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Macoilin PF09726.9 CDJ65617.1 - 0.0017 17.0 16.0 0.0025 16.4 16.0 1.3 1 0 0 1 1 1 1 Macoilin family SR-25 PF10500.9 CDJ65617.1 - 0.96 9.0 55.9 0.8 9.3 29.3 2.6 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 CDJ65618.1 - 7.8e-32 110.7 0.1 1e-17 64.4 0.0 3.7 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65618.1 - 5.6e-06 25.8 11.8 0.0043 16.4 0.0 4.1 5 0 0 5 5 5 3 Protein tyrosine kinase Exonuc_VII_L PF02601.15 CDJ65618.1 - 0.053 13.1 19.2 0.7 9.4 2.2 3.4 3 0 0 3 3 3 0 Exonuclease VII, large subunit DUF5094 PF17015.5 CDJ65618.1 - 0.25 11.5 6.9 0.22 11.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5094) FancD2 PF14631.6 CDJ65618.1 - 3.2 5.0 6.1 25 2.1 7.4 1.7 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease gag-asp_proteas PF13975.6 CDJ65619.1 - 0.041 14.5 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF3458_C PF17432.2 CDJ65621.1 - 1e-54 186.1 1.3 9.4e-37 127.1 2.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3458_C) ARM repeats LcrR PF09621.10 CDJ65621.1 - 0.039 13.4 0.1 0.064 12.7 0.1 1.3 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) zf-RING_11 PF17123.5 CDJ65622.1 - 0.00018 21.1 0.6 0.00018 21.1 0.6 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_2 PF13639.6 CDJ65622.1 - 0.013 15.8 0.2 0.013 15.8 0.2 2.5 3 0 0 3 3 3 0 Ring finger domain Suf PF05843.14 CDJ65623.1 - 2.7 7.9 10.3 4 7.3 10.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zein PF01559.16 CDJ65623.1 - 6.6 6.2 22.2 15 5.1 22.3 1.6 1 1 0 1 1 1 0 Zein seed storage protein SUIM_assoc PF16619.5 CDJ65624.1 - 0.021 14.9 50.0 1.1 9.3 0.1 5.5 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 E3_UFM1_ligase PF09743.9 CDJ65625.1 - 3.1e-11 43.4 0.8 4.3e-11 43.0 0.8 1.2 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 DUF1173 PF06666.11 CDJ65625.1 - 0.0076 15.2 1.2 0.0096 14.9 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1173) ODAM PF15424.6 CDJ65625.1 - 0.089 12.4 17.0 0.12 12.0 17.0 1.2 1 1 0 1 1 1 0 Odontogenic ameloblast-associated family DUF4834 PF16118.5 CDJ65625.1 - 0.17 12.9 2.5 0.22 12.5 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ65625.1 - 0.36 10.4 15.1 0.52 9.9 15.1 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ65625.1 - 0.37 10.7 12.8 0.32 11.0 12.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2613 PF11021.8 CDJ65625.1 - 3.1 8.0 6.6 0.87 9.7 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) RVP_2 PF08284.11 CDJ65626.1 - 4.6e-11 42.6 0.0 7.7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ65626.1 - 2.7e-10 40.8 0.0 1.2e-09 38.7 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ65626.1 - 2.1e-09 37.8 0.0 9.5e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 CDJ65626.1 - 3.4e-06 27.2 0.0 7.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 CDJ65626.1 - 0.00056 19.7 0.0 0.00095 19.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ65626.1 - 0.0017 18.6 0.0 0.0067 16.7 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 CDJ65626.1 - 9 6.6 10.9 1.1 9.4 2.6 2.5 2 0 0 2 2 2 0 Zinc knuckle MORN PF02493.20 CDJ65627.1 - 5.2e-13 48.1 8.5 3.5e-05 23.5 0.6 4.1 4 0 0 4 4 4 3 MORN repeat Ribosomal_L7Ae PF01248.26 CDJ65628.1 - 1.9e-23 82.0 0.0 2.2e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DPBB_1 PF03330.18 CDJ65628.1 - 0.074 13.3 0.0 3.7 7.9 0.0 2.1 1 1 0 2 2 2 0 Lytic transglycolase Hydrolase_6 PF13344.6 CDJ65628.1 - 0.084 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF4718 PF15842.5 CDJ65629.1 - 0.0086 15.9 6.0 0.0086 15.9 6.0 4.3 6 0 0 6 6 6 2 Domain of unknown function (DUF4718) ISK_Channel PF02060.15 CDJ65629.1 - 0.81 9.4 0.0 0.81 9.4 0.0 2.9 3 0 0 3 3 3 0 Slow voltage-gated potassium channel ArsA_ATPase PF02374.15 CDJ65630.1 - 8e-13 48.2 0.8 1e-12 47.9 0.0 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase PRIMA1 PF16101.5 CDJ65630.1 - 0.16 12.0 0.2 0.16 12.0 0.2 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 UPF0565 PF10561.9 CDJ65630.1 - 0.32 10.1 3.1 0.37 9.9 3.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 TFIIA PF03153.13 CDJ65630.1 - 4.6 7.1 19.7 5.3 6.9 19.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CEP19 PF14933.6 CDJ65630.1 - 8.9 6.6 11.0 14 5.9 11.0 1.2 1 0 0 1 1 1 0 CEP19-like protein eIF-3_zeta PF05091.12 CDJ65631.1 - 0.00062 18.9 20.5 0.002 17.2 15.5 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TCP PF03634.13 CDJ65631.1 - 0.0035 17.9 21.7 0.016 15.8 17.7 2.2 2 0 0 2 2 2 1 TCP family transcription factor Presenilin PF01080.17 CDJ65631.1 - 0.0041 16.0 19.7 0.0041 16.0 19.7 2.1 2 0 0 2 2 2 1 Presenilin Hydin_ADK PF17213.3 CDJ65631.1 - 0.0048 17.2 16.1 0.11 12.8 12.3 2.4 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain DUF2722 PF10846.8 CDJ65631.1 - 0.0081 15.2 0.6 0.0081 15.2 0.6 3.1 2 1 1 3 3 1 1 Protein of unknown function (DUF2722) DUF913 PF06025.12 CDJ65631.1 - 0.0086 15.1 8.5 0.0092 15.0 5.9 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) FAM60A PF15396.6 CDJ65631.1 - 0.026 14.5 15.1 0.13 12.3 12.9 2.5 2 0 0 2 2 2 0 Protein Family FAM60A Tim54 PF11711.8 CDJ65631.1 - 0.042 12.6 20.5 0.25 10.1 16.9 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 AAA_11 PF13086.6 CDJ65631.1 - 0.055 13.2 20.2 0.14 11.9 17.0 2.1 2 0 0 2 2 2 0 AAA domain Rad54_N PF08658.10 CDJ65631.1 - 0.073 13.2 10.5 0.1 12.7 7.0 2.3 2 0 0 2 2 2 0 Rad54 N terminal DUF4569 PF15133.6 CDJ65631.1 - 0.085 12.6 25.9 0.58 9.8 21.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) DAG_kinase_N PF14513.6 CDJ65631.1 - 0.11 12.7 23.5 0.6 10.3 19.4 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF1980 PF09323.10 CDJ65631.1 - 0.17 11.8 10.9 0.26 11.2 7.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) NPR3 PF03666.13 CDJ65631.1 - 0.19 10.5 20.4 0.24 10.2 18.0 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 CDJ65631.1 - 0.21 9.7 19.6 0.013 13.7 13.8 1.7 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein EPL1 PF10513.9 CDJ65631.1 - 0.25 11.7 23.8 1.4 9.3 18.4 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like PAT1 PF09770.9 CDJ65631.1 - 0.26 9.5 43.9 0.4 8.9 35.1 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 MMR1 PF08505.10 CDJ65631.1 - 0.29 11.4 31.4 0.03 14.6 20.7 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF4045 PF13254.6 CDJ65631.1 - 0.36 10.4 18.1 0.15 11.7 14.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) PA26 PF04636.13 CDJ65631.1 - 0.37 9.6 15.6 0.35 9.7 12.4 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) SAPS PF04499.15 CDJ65631.1 - 0.46 9.2 16.9 0.7 8.6 16.9 1.3 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 CDJ65631.1 - 0.47 10.5 28.3 3.4 7.7 22.3 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 CDJ65631.1 - 0.51 8.2 23.1 1.7 6.5 20.7 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CSG2 PF16965.5 CDJ65631.1 - 0.54 9.1 11.8 0.12 11.3 6.6 1.9 2 0 0 2 2 2 0 Ceramide synthase regulator Pox_Ag35 PF03286.14 CDJ65631.1 - 0.56 10.0 15.5 0.046 13.5 10.7 1.5 2 0 0 2 2 1 0 Pox virus Ag35 surface protein CCDC53 PF10152.9 CDJ65631.1 - 0.61 10.5 24.4 2.4 8.6 19.7 2.6 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF2052 PF09747.9 CDJ65631.1 - 0.67 10.1 30.7 0.3 11.2 23.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) BORG_CEP PF14957.6 CDJ65631.1 - 0.68 11.1 18.9 1.1 10.4 15.7 2.1 2 0 0 2 2 2 0 Cdc42 effector SLC12 PF03522.15 CDJ65631.1 - 0.69 8.9 23.9 0.34 9.9 19.5 2.0 2 0 0 2 2 2 0 Solute carrier family 12 CPSF100_C PF13299.6 CDJ65631.1 - 0.73 10.0 19.7 1.7 8.8 16.3 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Endostatin PF06482.11 CDJ65631.1 - 0.73 9.2 21.6 0.59 9.5 17.1 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Med15 PF09606.10 CDJ65631.1 - 1.1 7.9 59.8 0.052 12.2 4.4 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.12 CDJ65631.1 - 1.3 8.8 31.0 0.28 11.0 25.2 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.6 CDJ65631.1 - 1.3 7.3 8.7 0.21 10.0 5.0 1.5 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF3295 PF11702.8 CDJ65631.1 - 1.3 8.3 23.1 0.38 10.1 18.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) CDC45 PF02724.14 CDJ65631.1 - 1.4 7.1 25.3 0.26 9.5 19.8 2.0 2 0 0 2 2 2 0 CDC45-like protein SpoIIP PF07454.11 CDJ65631.1 - 2.2 7.7 26.4 1 8.7 20.6 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Gti1_Pac2 PF09729.9 CDJ65631.1 - 2.7 8.0 21.3 5.2 7.1 18.4 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family ALMT PF11744.8 CDJ65631.1 - 2.8 6.7 23.0 0.79 8.5 19.1 1.8 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF4820 PF16091.5 CDJ65631.1 - 3 7.2 20.5 2.4 7.5 15.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Sin_N PF04801.13 CDJ65631.1 - 4.7 6.3 41.4 1.1 8.4 0.3 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region LAP1C PF05609.12 CDJ65631.1 - 4.8 6.2 25.8 0.65 9.0 19.7 2.0 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) DUF3807 PF12720.7 CDJ65631.1 - 5.3 7.3 37.3 25 5.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Lin-8 PF03353.15 CDJ65631.1 - 5.4 6.5 31.9 5.1 6.6 26.1 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SARAF PF06682.12 CDJ65631.1 - 5.5 6.5 24.2 26 4.3 0.0 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Pex14_N PF04695.13 CDJ65631.1 - 7 7.3 44.3 0.08 13.6 25.3 2.8 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SUIM_assoc PF16619.5 CDJ65632.1 - 0.00097 19.2 4.2 0.00097 19.2 4.2 2.3 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ65632.1 - 0.19 11.7 33.6 0.25 11.3 33.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RS4NT PF08071.12 CDJ65633.1 - 1.6e-20 72.9 9.4 8.6e-20 70.6 8.5 2.1 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 CDJ65633.1 - 3.4e-07 29.9 0.1 4.9e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 S4 domain Ribosomal_S4e PF00900.20 CDJ65633.1 - 0.00025 20.9 0.0 0.00049 20.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal family S4e PepX_C PF08530.10 CDJ65634.1 - 1.7e-10 41.2 0.1 1e-08 35.4 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 CDJ65634.1 - 1.8e-07 31.0 0.2 6.9e-07 29.1 0.0 2.1 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) SR-25 PF10500.9 CDJ65635.1 - 4.8e-07 29.6 14.5 4.8e-07 29.6 14.5 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ65635.1 - 0.00069 19.9 3.2 0.00069 19.9 3.2 3.9 4 0 0 4 4 1 1 Domain of unknown function (DUF755) CCSAP PF15748.5 CDJ65635.1 - 0.0033 17.6 17.5 0.0033 17.6 17.5 2.5 3 0 0 3 3 3 1 Centriole, cilia and spindle-associated DDHD PF02862.17 CDJ65635.1 - 0.0056 16.9 7.0 0.0056 16.9 7.0 1.6 2 0 0 2 2 1 1 DDHD domain DUF3446 PF11928.8 CDJ65635.1 - 0.008 16.5 8.1 0.008 16.5 8.1 2.5 2 0 0 2 2 2 1 Early growth response N-terminal domain DUF4776 PF16003.5 CDJ65635.1 - 0.01 14.9 7.6 0.015 14.4 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Velvet PF11754.8 CDJ65635.1 - 0.06 13.3 14.8 0.02 14.8 10.5 2.1 2 0 0 2 2 2 0 Velvet factor SUFU_C PF12470.8 CDJ65635.1 - 0.1 12.6 5.8 0.21 11.6 5.8 1.5 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain RR_TM4-6 PF06459.12 CDJ65635.1 - 0.15 11.9 12.6 0.25 11.2 12.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 XRCC4 PF06632.12 CDJ65635.1 - 0.25 10.2 13.3 0.37 9.6 13.3 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SLC12 PF03522.15 CDJ65635.1 - 0.25 10.3 11.1 0.38 9.7 11.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 eIF-3_zeta PF05091.12 CDJ65635.1 - 0.27 10.2 14.1 0.37 9.7 14.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tim54 PF11711.8 CDJ65635.1 - 0.32 9.7 8.6 0.5 9.1 8.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 CDJ65635.1 - 0.57 9.6 16.8 0.87 9.0 16.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Band_3_cyto PF07565.13 CDJ65635.1 - 1.1 9.1 11.8 2.4 7.9 11.8 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Borrelia_P83 PF05262.11 CDJ65635.1 - 1.4 7.4 20.0 2.2 6.7 20.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_S49_N PF08496.10 CDJ65635.1 - 1.5 8.8 12.0 3.8 7.5 12.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2126 PF09899.9 CDJ65635.1 - 1.8 6.6 9.2 2.4 6.1 9.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Hid1 PF12722.7 CDJ65635.1 - 4.1 5.4 20.4 6 4.9 20.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AIF_C PF14721.6 CDJ65635.1 - 4.7 7.6 9.3 10 6.5 9.3 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TACI-CRD2 PF09305.10 CDJ65636.1 - 0.077 13.0 0.2 0.21 11.7 0.2 1.7 1 0 0 1 1 1 0 TACI, cysteine-rich domain SR-25 PF10500.9 CDJ65636.1 - 0.11 12.1 11.7 0.19 11.3 11.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ65636.1 - 2 8.8 21.1 20 5.6 18.5 3.0 2 0 0 2 2 2 0 Early growth response N-terminal domain Corona_nucleoca PF00937.18 CDJ65636.1 - 5.6 5.9 6.8 8.4 5.3 6.8 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RSRP PF17069.5 CDJ65636.1 - 6.2 6.3 16.6 9.7 5.7 16.6 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Ubie_methyltran PF01209.18 CDJ65638.1 - 4.6e-33 114.5 0.0 2.7e-18 66.2 0.0 3.3 3 1 0 3 3 3 3 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CDJ65638.1 - 3.4e-14 53.3 0.1 1.5e-07 32.0 0.0 3.2 2 1 1 3 3 3 3 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ65638.1 - 6.9e-13 49.1 0.1 1.4e-10 41.7 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ65638.1 - 1.2e-07 31.6 0.4 0.0011 18.8 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ65638.1 - 1.7e-06 28.0 0.0 3e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ65638.1 - 1.5e-05 25.7 0.0 0.0021 18.7 0.0 3.0 1 1 0 1 1 1 1 Methyltransferase domain DUF1645 PF07816.11 CDJ65638.1 - 0.0016 19.0 3.2 0.0022 18.6 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) AAA_23 PF13476.6 CDJ65638.1 - 0.0049 17.4 0.0 0.0059 17.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF4667 PF15700.5 CDJ65638.1 - 0.0091 16.1 6.5 0.013 15.6 6.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) Miga PF10265.9 CDJ65638.1 - 0.015 14.3 4.9 0.02 13.9 4.9 1.0 1 0 0 1 1 1 0 Mitoguardin SPX PF03105.19 CDJ65638.1 - 0.016 15.2 1.7 0.019 14.9 1.7 1.1 1 0 0 1 1 1 0 SPX domain Spt20 PF12090.8 CDJ65638.1 - 0.022 14.4 16.4 0.03 13.9 16.4 1.2 1 0 0 1 1 1 0 Spt20 family Lin-8 PF03353.15 CDJ65638.1 - 0.049 13.2 7.9 0.065 12.8 7.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ65638.1 - 0.062 13.3 18.2 0.081 12.9 18.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CDJ65638.1 - 0.16 9.1 8.9 0.2 8.7 8.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PIG-S PF10510.9 CDJ65638.1 - 0.19 10.5 4.7 0.25 10.2 4.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Polysacc_synt_2 PF02719.15 CDJ65638.1 - 0.22 10.6 1.2 0.29 10.2 1.2 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2722 PF10846.8 CDJ65638.1 - 0.34 9.8 15.6 0.5 9.3 15.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MDM31_MDM32 PF08118.11 CDJ65638.1 - 0.38 9.4 2.7 0.5 9.0 2.7 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Roughex PF06020.11 CDJ65638.1 - 0.53 9.3 5.4 0.67 9.0 5.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF3446 PF11928.8 CDJ65638.1 - 0.56 10.5 15.3 1.7 9.0 15.3 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain UPF0560 PF10577.9 CDJ65638.1 - 1.1 7.7 10.0 1.3 7.4 10.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 IMUP PF15761.5 CDJ65638.1 - 1.2 9.8 9.9 2.9 8.6 9.9 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein Presenilin PF01080.17 CDJ65638.1 - 4.3 6.0 6.4 6 5.5 6.4 1.1 1 0 0 1 1 1 0 Presenilin NIF PF03031.18 CDJ65639.1 - 4.7e-22 78.4 0.0 9.3e-22 77.5 0.0 1.5 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Presenilin PF01080.17 CDJ65639.1 - 0.25 10.1 5.0 0.37 9.5 5.0 1.2 1 0 0 1 1 1 0 Presenilin Cas3_C PF18395.1 CDJ65639.1 - 2.6 8.6 5.3 1.5 9.4 1.8 2.4 1 1 1 2 2 2 0 Cas3 C-terminal domain Steroid_dh PF02544.16 CDJ65640.1 - 1.5e-32 112.7 7.7 2e-27 96.0 1.3 3.4 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CDJ65640.1 - 1.4 8.4 4.7 2.6 7.5 2.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1295) CactinC_cactus PF09732.9 CDJ65641.1 - 2.8e-54 182.4 8.4 2.8e-54 182.4 8.4 1.8 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 CDJ65641.1 - 2e-46 158.3 2.0 2e-46 158.3 2.0 2.8 3 1 0 3 3 3 1 Conserved mid region of cactin Ketoacyl-synt_C PF02801.22 CDJ65642.1 - 4.8e-27 94.3 0.2 5.8e-27 94.1 0.2 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain tRNA-synt_1 PF00133.22 CDJ65643.1 - 3.3e-28 98.3 1.4 3.2e-11 42.2 0.0 5.3 4 1 1 5 5 5 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDJ65643.1 - 3.1e-18 65.7 0.0 8.3e-07 28.1 0.0 4.2 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CDJ65643.1 - 5.1e-11 42.8 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 CDJ65643.1 - 1.1e-06 28.3 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 PRKG1_interact PF15898.5 CDJ65643.1 - 0.12 13.3 5.2 0.44 11.5 0.1 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TFIIA PF03153.13 CDJ65643.1 - 0.55 10.2 17.1 0.068 13.2 7.6 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ65643.1 - 1.6 8.9 19.1 0.013 15.5 3.1 4.4 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF155 PF02582.14 CDJ65645.1 - 1.9e-47 161.6 0.0 3.5e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 BING4CT PF08149.11 CDJ65646.1 - 3.1e-33 113.4 0.0 3.2e-30 103.7 0.0 2.9 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.32 CDJ65646.1 - 0.0064 17.3 0.0 2.3 9.3 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat SOBP PF15279.6 CDJ65646.1 - 0.59 10.7 7.0 0.082 13.5 1.7 1.9 2 0 0 2 2 2 0 Sine oculis-binding protein YL1 PF05764.13 CDJ65646.1 - 1.9 8.5 24.7 1.6 8.8 16.4 2.1 2 0 0 2 2 2 0 YL1 nuclear protein Ion_trans PF00520.31 CDJ65647.1 - 3.6e-25 88.6 12.1 1.8e-16 60.1 0.2 2.7 2 1 0 2 2 2 2 Ion transport protein CBP_BcsG PF11658.8 CDJ65647.1 - 0.25 9.7 6.9 0.53 8.6 0.2 2.3 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG CLN3 PF02487.17 CDJ65647.1 - 0.8 8.7 5.7 0.64 9.0 2.0 2.5 2 0 0 2 2 2 0 CLN3 protein PKD_channel PF08016.12 CDJ65647.1 - 1.9 7.1 15.3 0.063 12.0 2.8 2.4 2 0 0 2 2 2 0 Polycystin cation channel TMEM208_SND2 PF05620.11 CDJ65647.1 - 2.1 8.1 11.2 17 5.1 0.1 3.6 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Plasmodium_Vir PF05795.11 CDJ65647.1 - 3.3 7.0 4.2 4.1 6.7 2.8 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein FixQ PF05545.11 CDJ65647.1 - 6.5 6.8 7.1 7.1 6.7 0.3 3.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Rhodanese PF00581.20 CDJ65649.1 - 0.026 15.0 0.0 0.24 11.9 0.0 2.7 1 1 0 1 1 1 0 Rhodanese-like domain PAP_assoc PF03828.19 CDJ65649.1 - 0.029 14.6 2.1 0.3 11.3 2.1 2.6 1 1 0 1 1 1 0 Cid1 family poly A polymerase Metallothio_2 PF01439.18 CDJ65649.1 - 2.7 8.9 9.3 0.21 12.5 0.8 3.9 2 0 0 2 2 2 0 Metallothionein SPX PF03105.19 CDJ65650.1 - 0.0019 18.2 9.8 0.0021 18.1 9.8 1.1 1 0 0 1 1 1 1 SPX domain DUF4614 PF15391.6 CDJ65650.1 - 0.0081 16.2 12.9 0.012 15.7 12.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) Apt1 PF10351.9 CDJ65650.1 - 0.013 14.4 10.7 0.014 14.3 10.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain RIFIN PF02009.16 CDJ65650.1 - 0.073 13.0 0.8 0.094 12.6 0.8 1.2 1 0 0 1 1 1 0 Rifin RskA PF10099.9 CDJ65650.1 - 0.16 12.3 18.3 0.14 12.5 5.2 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ65650.1 - 0.21 10.3 2.9 0.23 10.2 2.9 1.2 1 0 0 1 1 1 0 Presenilin SpoIIIAH PF12685.7 CDJ65650.1 - 0.38 10.6 7.4 0.53 10.1 7.4 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein SOG2 PF10428.9 CDJ65650.1 - 0.38 9.9 18.8 0.49 9.5 18.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Sec3_C PF09763.9 CDJ65650.1 - 1.1 7.6 4.3 1.1 7.5 4.3 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 Tmemb_cc2 PF10267.9 CDJ65650.1 - 1.3 8.1 4.9 1.4 8.0 4.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Mcm10 PF09332.11 CDJ65650.1 - 1.4 8.2 10.4 2.2 7.6 10.4 1.2 1 0 0 1 1 1 0 Mcm10 replication factor Miga PF10265.9 CDJ65650.1 - 1.5 7.7 9.8 1.9 7.3 9.8 1.1 1 0 0 1 1 1 0 Mitoguardin Peroxin-3 PF04882.12 CDJ65650.1 - 2 7.3 9.9 2.5 7.0 9.9 1.1 1 0 0 1 1 1 0 Peroxin-3 Ribosomal_60s PF00428.19 CDJ65650.1 - 2.7 8.7 35.1 3.3 8.4 14.9 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein NPR3 PF03666.13 CDJ65650.1 - 3.2 6.5 7.7 4.2 6.1 7.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ANAPC1 PF12859.7 CDJ65650.1 - 5.9 7.5 12.4 10 6.7 12.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 RAP1 PF07218.11 CDJ65650.1 - 8.4 4.5 23.9 9.8 4.3 23.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YibE_F PF07907.11 CDJ65651.1 - 0.0045 16.5 4.8 0.011 15.2 0.6 2.2 2 0 0 2 2 2 1 YibE/F-like protein DUF3021 PF11457.8 CDJ65651.1 - 0.15 12.4 3.0 0.19 12.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) DUF998 PF06197.13 CDJ65651.1 - 0.17 11.5 18.1 1.5 8.4 13.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF1345 PF07077.11 CDJ65651.1 - 1.6 8.4 11.0 1.9 8.2 7.4 2.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1345) DctQ PF04290.12 CDJ65651.1 - 1.7 8.6 9.3 0.72 9.8 5.6 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Chorion_2 PF03964.15 CDJ65651.1 - 6.4 7.7 12.0 2.6 8.9 1.3 2.5 2 0 0 2 2 2 0 Chorion family 2 DUF4636 PF15468.6 CDJ65652.1 - 0.0068 16.1 0.9 0.0068 16.1 0.9 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4636) SARAF PF06682.12 CDJ65652.1 - 0.016 14.9 16.9 2.4 7.7 15.5 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Pep1_7 PF17232.2 CDJ65652.1 - 0.32 11.5 3.2 0.35 11.4 0.4 2.5 2 0 0 2 2 2 0 Elicitor peptide 1-7 Nucleoplasmin PF03066.15 CDJ65653.1 - 0.044 14.3 0.0 0.049 14.1 0.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain PAT1 PF09770.9 CDJ65653.1 - 2.1 6.5 14.0 2 6.6 14.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 CDJ65653.1 - 2.4 8.0 18.9 2.5 8.0 18.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ65654.1 - 0.0066 16.1 29.8 0.0081 15.8 29.8 1.3 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ65654.1 - 0.0087 16.1 32.5 0.012 15.7 32.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Miga PF10265.9 CDJ65654.1 - 0.058 12.4 8.9 0.07 12.1 8.9 1.0 1 0 0 1 1 1 0 Mitoguardin MMR1 PF08505.10 CDJ65654.1 - 0.094 13.0 10.0 0.095 13.0 10.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Draxin PF15550.6 CDJ65654.1 - 0.13 12.1 9.0 0.15 11.9 9.0 1.0 1 0 0 1 1 1 0 Draxin NST1 PF13945.6 CDJ65654.1 - 0.37 10.9 16.9 0.48 10.5 16.9 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF3408 PF11888.8 CDJ65654.1 - 0.41 10.8 11.5 0.65 10.1 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Band_3_cyto PF07565.13 CDJ65654.1 - 0.52 10.1 6.1 0.53 10.0 6.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SpoIIP PF07454.11 CDJ65654.1 - 0.68 9.3 9.3 0.71 9.3 9.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 CDJ65654.1 - 0.78 8.7 9.4 0.81 8.6 9.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 CDJ65654.1 - 0.95 8.2 7.3 1 8.1 7.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SWI-SNF_Ssr4 PF08549.10 CDJ65654.1 - 1.1 7.8 24.1 1.2 7.7 24.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Activator_LAG-3 PF11498.8 CDJ65654.1 - 1.7 7.5 37.9 2.5 6.9 37.9 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 eIF-3_zeta PF05091.12 CDJ65654.1 - 1.9 7.3 16.0 2.4 7.1 16.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UPF0560 PF10577.9 CDJ65654.1 - 2 6.8 19.7 2.4 6.5 19.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FAM176 PF14851.6 CDJ65654.1 - 2.1 8.0 5.4 2.9 7.5 5.4 1.3 1 0 0 1 1 1 0 FAM176 family Neur_chan_memb PF02932.16 CDJ65654.1 - 2.2 8.3 7.8 2.3 8.2 7.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dicty_REP PF05086.12 CDJ65654.1 - 2.3 6.1 7.2 2.5 6.0 7.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Membralin PF09746.9 CDJ65654.1 - 3 6.8 5.0 3.1 6.7 5.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein AP-5_subunit_s1 PF15001.6 CDJ65654.1 - 3.2 7.7 12.0 4.1 7.3 12.0 1.1 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Presenilin PF01080.17 CDJ65654.1 - 3.4 6.3 14.2 4 6.1 14.2 1.1 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 CDJ65654.1 - 3.5 6.6 6.7 3.6 6.5 6.7 1.2 1 0 0 1 1 1 0 CLN3 protein Sec62 PF03839.16 CDJ65654.1 - 3.6 7.0 7.0 3.9 6.9 7.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4834 PF16118.5 CDJ65654.1 - 3.9 8.5 13.6 6 7.9 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ65654.1 - 5.3 4.8 10.1 6.1 4.6 10.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ARF7EP_C PF14949.6 CDJ65654.1 - 6.6 7.4 10.9 10 6.8 10.9 1.3 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Herpes_DNAp_acc PF04929.12 CDJ65654.1 - 7 5.5 12.8 7.3 5.5 12.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF966 PF06136.13 CDJ65654.1 - 7.9 6.1 14.0 8.7 6.0 14.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MDM10 PF12519.8 CDJ65654.1 - 8.1 5.2 9.1 8.6 5.1 9.1 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 GREB1 PF15782.5 CDJ65654.1 - 9.9 3.1 14.5 10 3.1 14.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2722 PF10846.8 CDJ65656.1 - 4.9e-07 29.1 1.8 4.9e-07 29.1 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) SpoIIP PF07454.11 CDJ65656.1 - 0.0051 16.3 0.2 0.006 16.1 0.2 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 CDJ65656.1 - 0.05 13.6 28.3 0.049 13.6 22.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ctr PF04145.15 CDJ65656.1 - 0.052 14.2 2.8 5.2 7.7 0.3 2.1 2 0 0 2 2 2 0 Ctr copper transporter family FA_desaturase PF00487.24 CDJ65656.1 - 0.17 11.7 0.6 0.3 10.9 0.6 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Suf PF05843.14 CDJ65656.1 - 0.3 11.0 9.9 0.46 10.4 9.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GREB1 PF15782.5 CDJ65656.1 - 1.1 6.3 3.8 1.5 5.8 3.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4228 PF14009.6 CDJ65656.1 - 1.8 8.9 8.3 0.79 10.1 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Spt20 PF12090.8 CDJ65656.1 - 2.1 7.9 28.7 3.2 7.3 28.7 1.2 1 0 0 1 1 1 0 Spt20 family Paf1 PF03985.13 CDJ65656.1 - 5.7 5.8 10.9 7.8 5.4 10.9 1.1 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 CDJ65656.1 - 6.2 5.5 11.4 11 4.6 11.4 1.3 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ65656.1 - 6.5 5.6 11.1 9.2 5.1 11.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ65656.1 - 6.5 6.8 11.5 13 5.8 11.5 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ65657.1 - 0.0044 16.7 0.9 0.0044 16.7 0.9 3.0 2 1 0 2 2 2 1 Spt20 family TFIIA PF03153.13 CDJ65657.1 - 0.011 15.8 34.0 0.13 12.2 0.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ65657.1 - 0.84 9.1 17.5 6.9 6.1 14.9 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Neur_chan_memb PF02932.16 CDJ65657.1 - 5.6 6.9 16.2 6.9 6.7 14.1 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4366 PF14283.6 CDJ65657.1 - 5.7 7.0 6.5 34 4.4 4.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) MDM10 PF12519.8 CDJ65657.1 - 6.7 5.4 11.0 10 4.9 11.0 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Sec23_BS PF08033.12 CDJ65658.1 - 3.5e-13 50.1 0.0 3e-12 47.1 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CDJ65658.1 - 1.4e-09 37.6 1.3 1.4e-09 37.6 1.3 2.9 1 1 1 3 3 3 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 CDJ65658.1 - 0.0002 21.2 0.0 0.0002 21.2 0.0 2.6 2 0 0 2 2 1 1 Gelsolin repeat DDHD PF02862.17 CDJ65658.1 - 0.0041 17.3 1.7 0.0054 16.9 1.7 1.4 1 0 0 1 1 1 1 DDHD domain Connexin PF00029.19 CDJ65658.1 - 0.023 14.4 3.4 0.034 13.9 3.4 1.2 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ65658.1 - 0.028 13.2 7.2 0.039 12.7 7.2 1.2 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 CDJ65658.1 - 0.029 13.9 5.2 0.04 13.4 5.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RskA PF10099.9 CDJ65658.1 - 0.06 13.6 41.8 7.7 6.8 0.6 3.8 2 1 1 3 3 3 0 Anti-sigma-K factor rskA RR_TM4-6 PF06459.12 CDJ65658.1 - 0.065 13.1 4.3 0.11 12.4 4.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 CDJ65658.1 - 0.082 11.4 5.3 0.12 10.9 5.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein eIF-3_zeta PF05091.12 CDJ65658.1 - 0.16 10.9 11.6 0.22 10.4 11.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF5327 PF17261.2 CDJ65658.1 - 0.2 12.4 16.1 0.13 13.1 12.6 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF4834 PF16118.5 CDJ65658.1 - 0.23 12.4 11.5 0.57 11.2 10.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EOS1 PF12326.8 CDJ65658.1 - 0.27 11.1 1.0 0.58 10.1 0.9 1.7 2 0 0 2 2 1 0 N-glycosylation protein MMR1 PF08505.10 CDJ65658.1 - 0.38 11.0 12.4 0.64 10.3 12.4 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Peptidase_S49_N PF08496.10 CDJ65658.1 - 0.41 10.7 7.3 0.26 11.3 5.2 1.7 2 0 0 2 2 1 0 Peptidase family S49 N-terminal FAM60A PF15396.6 CDJ65658.1 - 0.42 10.6 3.8 0.6 10.1 3.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Serinc PF03348.15 CDJ65658.1 - 0.45 9.4 1.7 0.58 9.0 1.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) AIF_C PF14721.6 CDJ65658.1 - 0.46 10.8 5.7 1 9.7 5.7 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1764 PF08576.10 CDJ65658.1 - 0.5 11.3 7.5 1 10.3 7.5 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CPSF100_C PF13299.6 CDJ65658.1 - 0.63 10.2 6.7 0.34 11.1 4.1 1.9 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal TERB2 PF15101.6 CDJ65658.1 - 0.67 10.0 12.2 1.4 8.9 12.2 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CLN3 PF02487.17 CDJ65658.1 - 0.71 8.9 4.1 1.2 8.1 4.1 1.3 1 0 0 1 1 1 0 CLN3 protein CSG2 PF16965.5 CDJ65658.1 - 0.74 8.7 1.8 1.1 8.1 1.8 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF1980 PF09323.10 CDJ65658.1 - 0.76 9.7 7.6 1.8 8.4 5.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) OATP PF03137.20 CDJ65658.1 - 0.8 7.9 2.2 1.1 7.5 2.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Baculo_PP31 PF05311.11 CDJ65658.1 - 1 8.8 9.4 1.5 8.2 9.4 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) EIIBC-GUT_N PF03612.14 CDJ65658.1 - 1 9.1 7.2 2.1 8.0 7.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DcuA_DcuB PF03605.14 CDJ65658.1 - 1.1 8.1 7.7 0.045 12.6 0.9 1.8 1 1 1 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter Ribosomal_60s PF00428.19 CDJ65658.1 - 1.1 9.8 23.8 3.7 8.2 4.0 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF3464 PF11947.8 CDJ65658.1 - 1.4 8.6 9.1 3.1 7.6 9.1 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Hid1 PF12722.7 CDJ65658.1 - 3 5.9 9.4 4.6 5.2 9.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3043 PF11241.8 CDJ65658.1 - 3 7.8 11.4 8.1 6.5 11.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) MDFI PF15316.6 CDJ65658.1 - 4.3 7.4 7.3 8 6.5 7.3 1.4 1 0 0 1 1 1 0 MyoD family inhibitor PBP_sp32 PF07222.12 CDJ65658.1 - 7.9 5.9 13.8 13 5.2 13.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sec23_trunk PF04811.15 CDJ65659.1 - 1e-48 166.1 1.0 1.2e-38 133.1 0.1 3.1 2 1 1 3 3 3 3 Sec23/Sec24 trunk domain DUF2722 PF10846.8 CDJ65659.1 - 0.0015 17.6 2.2 0.0018 17.3 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ65659.1 - 0.0099 15.5 7.9 0.014 15.0 7.9 1.2 1 0 0 1 1 1 1 Spt20 family Med15 PF09606.10 CDJ65659.1 - 5.1 5.7 17.2 0.014 14.1 4.8 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DivIC PF04977.15 CDJ65659.1 - 9.9 6.0 11.4 9 6.1 7.9 2.1 2 0 0 2 2 2 0 Septum formation initiator ChAPs PF09295.10 CDJ65660.1 - 4.2e-18 65.5 0.0 9.3e-12 44.6 0.0 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) SUIM_assoc PF16619.5 CDJ65660.1 - 0.051 13.6 13.7 0.14 12.3 2.1 3.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ65662.1 - 1.8e-05 24.5 8.7 1.8e-05 24.5 8.7 16.0 13 3 2 17 17 17 2 Nuclear RNA-splicing-associated protein PHD_2 PF13831.6 CDJ65662.1 - 0.0023 17.4 43.2 0.15 11.7 2.2 6.9 7 0 0 7 7 7 4 PHD-finger Ribosomal_S14 PF00253.21 CDJ65662.1 - 7.3 6.4 12.2 17 5.3 2.9 3.8 3 0 0 3 3 3 0 Ribosomal protein S14p/S29e AA_kinase PF00696.28 CDJ65663.1 - 6.8e-23 81.5 7.4 2.2e-20 73.3 0.0 3.0 3 0 0 3 3 3 2 Amino acid kinase family Ribosomal_60s PF00428.19 CDJ65663.1 - 0.0008 20.0 10.4 0.0008 20.0 10.4 4.4 3 1 1 4 4 4 1 60s Acidic ribosomal protein PA PF02225.22 CDJ65664.1 - 0.66 10.0 5.8 0.85 9.7 4.4 1.9 1 1 1 2 2 2 0 PA domain RAP1 PF07218.11 CDJ65664.1 - 4.2 5.5 9.5 6 5.0 9.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 CDJ65664.1 - 8.2 4.8 56.5 11 4.5 56.5 1.1 1 0 0 1 1 1 0 Macoilin family Mitofilin PF09731.9 CDJ65665.1 - 0.083 11.7 23.5 0.1 11.4 23.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CCSAP PF15748.5 CDJ65665.1 - 1.3 9.2 17.9 1.5 8.9 17.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDC27 PF09507.10 CDJ65666.1 - 0.024 14.1 40.2 0.031 13.7 40.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Asp-B-Hydro_N PF05279.11 CDJ65666.1 - 3.1 7.8 31.2 4.8 7.2 31.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SOBP PF15279.6 CDJ65666.1 - 9.8 6.7 33.2 15 6.1 33.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SH3_10 PF17902.1 CDJ65667.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 SH3 domain TMEM51 PF15345.6 CDJ65668.1 - 2.6e-08 34.0 0.1 3.4e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 Acyltransferase PF01553.21 CDJ65669.1 - 5.2e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase tRNA-synt_1 PF00133.22 CDJ65670.1 - 5.5e-43 147.1 3.2 6.3e-18 64.4 0.0 6.6 4 2 2 6 6 6 6 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ65670.1 - 7.2e-09 35.8 0.0 1.4e-06 28.4 0.0 2.5 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ65670.1 - 9.2e-05 21.3 0.0 0.55 8.9 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) NMD3 PF04981.13 CDJ65672.1 - 4.9e-40 137.5 0.1 8.8e-40 136.7 0.1 1.4 1 0 0 1 1 1 1 NMD3 family CENP-R PF06729.12 CDJ65672.1 - 0.4 10.6 8.7 4 7.4 1.6 2.6 2 0 0 2 2 2 0 Kinetochore component, CENP-R Tau95_N PF17682.1 CDJ65672.1 - 0.62 10.3 0.0 0.62 10.3 0.0 2.6 3 1 0 3 3 3 0 Tau95 Triple barrel domain Neur_chan_memb PF02932.16 CDJ65672.1 - 6.2 6.8 6.1 32 4.5 2.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ65673.1 - 0.13 12.2 15.6 0.17 11.9 15.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit vATP-synt_AC39 PF01992.16 CDJ65674.1 - 7.8e-79 265.6 0.1 9.6e-79 265.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SUIM_assoc PF16619.5 CDJ65674.1 - 0.00018 21.5 2.7 0.00052 20.0 2.7 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF3446 PF11928.8 CDJ65674.1 - 0.0025 18.1 4.5 0.0025 18.1 4.5 1.8 2 0 0 2 2 2 1 Early growth response N-terminal domain Activator_LAG-3 PF11498.8 CDJ65674.1 - 0.32 9.9 8.0 0.15 11.0 4.6 1.8 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SUIM_assoc PF16619.5 CDJ65675.1 - 0.0036 17.3 0.2 0.0036 17.3 0.2 5.6 4 2 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 IMUP PF15761.5 CDJ65676.1 - 0.00052 20.7 5.6 0.00071 20.2 5.6 1.3 1 0 0 1 1 1 1 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ65676.1 - 0.001 18.8 6.5 0.001 18.8 6.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MID_MedPIWI PF18296.1 CDJ65676.1 - 0.043 13.6 2.2 0.048 13.4 2.2 1.0 1 0 0 1 1 1 0 MID domain of medPIWI AF-4 PF05110.13 CDJ65676.1 - 0.13 10.3 10.2 0.12 10.5 10.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF755 PF05501.11 CDJ65676.1 - 4.5 7.6 18.3 5.3 7.3 18.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF755) MFS_1 PF07690.16 CDJ65678.1 - 2.1e-35 122.3 32.9 1.5e-30 106.3 22.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ65678.1 - 2.9e-08 33.0 2.7 2.9e-08 33.0 2.7 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 CDJ65678.1 - 0.027 13.3 7.5 0.15 10.9 8.2 2.0 1 1 0 1 1 1 0 MFS_1 like family SET PF00856.28 CDJ65680.1 - 1.2e-12 48.6 0.0 5.6e-11 43.1 0.0 2.9 2 1 0 2 2 2 1 SET domain DUF4175 PF13779.6 CDJ65680.1 - 4.7 5.0 17.5 6.2 4.6 17.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MCM_bind PF09739.9 CDJ65680.1 - 7.6 4.9 10.3 20 3.5 8.1 2.0 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor DDRGK PF09756.9 CDJ65680.1 - 7.8 6.1 16.1 13 5.4 16.1 1.2 1 0 0 1 1 1 0 DDRGK domain RPN7 PF10602.9 CDJ65681.1 - 1.6e-06 28.0 1.6 0.02 14.6 0.1 4.0 3 1 0 3 3 3 2 26S proteasome subunit RPN7 Mad3_BUB1_I PF08311.12 CDJ65681.1 - 5.4e-06 26.4 14.3 0.56 10.2 0.0 7.6 6 2 2 8 8 8 2 Mad3/BUB1 homology region 1 Suf PF05843.14 CDJ65681.1 - 2.2e-05 24.6 13.2 11 5.8 0.0 5.4 4 1 0 4 4 4 3 Suppressor of forked protein (Suf) TPR_8 PF13181.6 CDJ65681.1 - 0.00034 20.6 15.5 0.66 10.3 0.1 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat PPR PF01535.20 CDJ65681.1 - 0.0015 18.6 0.7 2.9 8.3 0.0 4.8 5 0 0 5 5 5 1 PPR repeat TPR_7 PF13176.6 CDJ65681.1 - 0.028 14.4 17.8 3 8.1 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ65681.1 - 0.039 14.2 29.0 0.12 12.7 0.9 7.1 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ65681.1 - 0.12 13.3 0.2 0.12 13.3 0.2 13.8 11 6 6 17 17 17 0 Tetratricopeptide repeat CKAP2_C PF15297.6 CDJ65681.1 - 0.15 11.2 5.1 0.25 10.4 0.0 2.8 3 0 0 3 3 3 0 Cytoskeleton-associated protein 2 C-terminus TPR_2 PF07719.17 CDJ65681.1 - 0.22 11.8 35.9 0.65 10.3 0.1 10.0 12 0 0 12 12 12 0 Tetratricopeptide repeat Ras PF00071.22 CDJ65682.1 - 1.1e-43 148.7 0.0 1.3e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ65682.1 - 6e-28 97.5 0.0 1.3e-27 96.4 0.0 1.5 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ65682.1 - 6.3e-10 38.8 0.1 9.5e-10 38.2 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ65682.1 - 0.00099 19.2 0.0 0.0019 18.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ65682.1 - 0.0021 17.4 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NTPase_1 PF03266.15 CDJ65682.1 - 0.0047 16.8 0.9 0.14 12.1 0.1 2.2 2 0 0 2 2 2 1 NTPase ArgoMid PF16487.5 CDJ65682.1 - 0.015 15.6 0.1 0.032 14.5 0.1 1.6 1 1 0 1 1 1 0 Mid domain of argonaute AAA_16 PF13191.6 CDJ65682.1 - 0.016 15.6 0.0 0.028 14.8 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 CDJ65682.1 - 0.039 14.4 0.3 0.43 11.0 0.2 2.3 1 1 1 2 2 2 0 RNA helicase AAA_7 PF12775.7 CDJ65682.1 - 0.044 13.3 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CDJ65682.1 - 0.044 13.0 0.1 0.1 11.7 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 CDJ65682.1 - 0.089 12.0 0.1 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 CDJ65682.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 CDJ65682.1 - 0.13 12.2 0.5 0.41 10.7 0.1 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CDJ65682.1 - 0.15 12.2 1.2 0.4 10.8 0.1 2.1 2 1 1 3 3 3 0 AAA domain NACHT PF05729.12 CDJ65682.1 - 0.21 11.5 0.2 0.44 10.4 0.2 1.5 1 0 0 1 1 1 0 NACHT domain MACPF PF01823.19 CDJ65683.1 - 0.41 10.7 5.1 1.2 9.2 5.1 1.7 1 0 0 1 1 1 0 MAC/Perforin domain PAN_1 PF00024.26 CDJ65684.1 - 4.1e-63 209.3 84.7 1.7e-08 34.3 1.6 11.2 8 3 3 11 11 11 11 PAN domain PAN_4 PF14295.6 CDJ65684.1 - 3.3e-45 151.8 65.7 2.7e-07 30.4 0.6 11.8 11 0 0 11 11 11 11 PAN domain PAN_3 PF08277.12 CDJ65684.1 - 0.00048 19.9 65.3 0.22 11.3 0.1 11.3 11 0 0 11 11 11 8 PAN-like domain PAN_2 PF08276.11 CDJ65684.1 - 0.00069 19.7 83.2 0.0011 19.0 1.9 11.6 11 1 0 11 11 11 7 PAN-like domain RAP PF08373.10 CDJ65686.1 - 0.0031 17.6 0.0 0.0092 16.1 0.0 1.7 1 0 0 1 1 1 1 RAP domain RestrictionSfiI PF11487.8 CDJ65686.1 - 0.14 12.0 0.2 0.24 11.2 0.2 1.3 1 0 0 1 1 1 0 Type II restriction enzyme SfiI Pkinase PF00069.25 CDJ65688.1 - 2.9e-41 141.6 0.0 4.3e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65688.1 - 3.1e-24 85.7 0.0 4.1e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.6 CDJ65688.1 - 0.00039 20.1 0.0 0.0016 18.2 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CDJ65688.1 - 0.00054 19.3 0.2 0.0016 17.9 0.2 1.8 1 0 0 1 1 1 1 EF hand APH PF01636.23 CDJ65688.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_5 PF13202.6 CDJ65688.1 - 0.0051 16.2 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CDJ65688.1 - 0.026 14.9 0.1 0.081 13.4 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair Kdo PF06293.14 CDJ65688.1 - 0.049 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2_10 PF16588.5 CDJ65688.1 - 0.2 11.4 2.1 0.44 10.3 2.1 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger DHHC PF01529.20 CDJ65689.1 - 2.4e-06 27.7 3.6 2.9e-06 27.4 3.6 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase LapA_dom PF06305.11 CDJ65689.1 - 0.32 10.8 4.3 0.3 10.9 0.5 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RCC1 PF00415.18 CDJ65691.1 - 1e-05 26.0 0.8 0.024 15.2 0.1 2.9 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Sin_N PF04801.13 CDJ65691.1 - 0.00018 20.9 9.0 0.00024 20.5 9.0 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region zf-RanBP PF00641.18 CDJ65691.1 - 0.0034 16.7 8.3 0.0061 15.9 8.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SUIM_assoc PF16619.5 CDJ65691.1 - 0.012 15.6 1.5 0.012 15.6 1.5 5.4 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 RCC1_2 PF13540.6 CDJ65691.1 - 0.28 11.0 6.1 0.05 13.4 2.0 2.0 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CDJ65692.1 - 2.7e-23 82.3 10.0 6.8e-08 33.0 0.8 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ65692.1 - 2e-10 40.2 17.6 2.2e-08 33.7 8.9 2.5 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Caldesmon PF02029.15 CDJ65693.1 - 2.3 6.9 48.5 2.7 6.7 48.5 1.0 1 0 0 1 1 1 0 Caldesmon GREB1 PF15782.5 CDJ65693.1 - 3.5 4.6 45.9 4.1 4.4 45.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Dapper PF15268.6 CDJ65693.1 - 7.1 5.3 53.6 7.5 5.3 53.6 1.1 1 0 0 1 1 1 0 Dapper DUF572 PF04502.13 CDJ65693.1 - 9.5 5.7 38.6 14 5.2 38.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SUIM_assoc PF16619.5 CDJ65694.1 - 4.6e-09 36.2 0.0 2.8e-05 24.1 0.0 3.1 2 1 1 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ65694.1 - 0.028 14.7 16.3 0.027 14.8 9.3 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF4407 PF14362.6 CDJ65694.1 - 0.23 10.7 4.6 2.4 7.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3138 PF11336.8 CDJ65694.1 - 9.3 4.7 15.1 0.82 8.2 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF4638 PF15472.6 CDJ65695.1 - 0.46 10.2 13.2 0.49 10.1 13.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Spt20 PF12090.8 CDJ65695.1 - 0.47 10.0 16.1 0.5 9.9 16.1 1.1 1 0 0 1 1 1 0 Spt20 family Nuc_deoxyrib_tr PF05014.15 CDJ65695.1 - 0.88 9.6 3.1 1.1 9.2 3.1 1.1 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase U79_P34 PF03064.16 CDJ65695.1 - 1.1 8.6 14.2 1.2 8.4 14.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DegT_DnrJ_EryC1 PF01041.17 CDJ65695.1 - 1.4 8.1 7.1 1.6 8.0 7.1 1.0 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4834 PF16118.5 CDJ65695.1 - 1.5 9.8 9.1 1.8 9.6 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EIIBC-GUT_N PF03612.14 CDJ65695.1 - 2.7 7.7 7.1 2.9 7.6 7.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Activator_LAG-3 PF11498.8 CDJ65695.1 - 2.8 6.8 29.3 3 6.7 29.3 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TERB2 PF15101.6 CDJ65695.1 - 3 7.8 10.6 3 7.9 10.6 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2828 PF11443.8 CDJ65695.1 - 3.1 5.8 12.8 3.3 5.7 12.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Connexin PF00029.19 CDJ65695.1 - 4.7 6.9 8.7 4.9 6.8 8.7 1.0 1 0 0 1 1 1 0 Connexin DUF3464 PF11947.8 CDJ65695.1 - 4.8 6.9 10.8 5.7 6.7 10.8 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4407 PF14362.6 CDJ65695.1 - 5.6 6.2 11.5 6.8 6.0 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMEM51 PF15345.6 CDJ65695.1 - 6.7 6.5 11.8 7.4 6.3 11.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 CLN3 PF02487.17 CDJ65695.1 - 8.5 5.3 6.7 9.4 5.2 6.7 1.0 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 CDJ65695.1 - 9 4.9 10.9 8.7 5.0 10.9 1.0 1 0 0 1 1 1 0 Presenilin DUF1180 PF06679.12 CDJ65696.1 - 0.042 14.3 1.0 0.042 14.3 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4400 PF14348.6 CDJ65696.1 - 0.12 11.8 0.3 0.24 10.9 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4400) Spt20 PF12090.8 CDJ65696.1 - 8.3 5.9 15.9 2.6 7.6 7.3 2.2 2 0 0 2 2 2 0 Spt20 family TPR_12 PF13424.6 CDJ65698.1 - 0.00097 19.4 3.5 0.18 12.2 0.2 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 CDJ65700.1 - 4.5e-89 299.3 1.8 4.5e-89 299.3 1.8 1.5 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family Exonuc_VII_L PF02601.15 CDJ65700.1 - 1.4 8.4 12.2 2.7 7.5 12.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit RskA PF10099.9 CDJ65701.1 - 3.2e-05 24.3 9.1 3.2e-05 24.3 9.1 7.2 2 2 4 6 6 6 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ65701.1 - 0.00073 19.2 11.6 0.00073 19.2 11.6 5.0 4 1 1 5 5 5 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ65701.1 - 0.0023 17.6 11.0 0.0023 17.6 11.0 5.1 5 1 0 5 5 5 2 Spt20 family DUF2722 PF10846.8 CDJ65701.1 - 0.0026 16.8 4.2 0.0026 16.8 4.2 4.7 4 1 0 4 4 4 2 Protein of unknown function (DUF2722) DNA_pol3_a_NII PF11490.8 CDJ65701.1 - 0.0077 16.1 2.6 0.0077 16.1 2.6 5.0 5 0 0 5 5 5 1 DNA polymerase III polC-type N-terminus II Zip PF02535.22 CDJ65701.1 - 1.4 8.0 8.0 0.8 8.9 0.1 3.1 3 1 0 3 3 3 0 ZIP Zinc transporter RAB3GAP2_N PF14655.6 CDJ65701.1 - 1.8 7.7 19.6 5.8 6.1 0.8 3.5 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus COX14 PF14880.6 CDJ65702.1 - 1.3e-05 25.0 0.6 2.5e-05 24.0 0.6 1.5 1 1 0 1 1 1 1 Cytochrome oxidase c assembly Adaptin_N PF01602.20 CDJ65703.1 - 1.8e-39 135.7 0.0 2.7e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CDJ65703.1 - 9.4e-11 42.0 0.0 2.3e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Coatomer gamma subunit appendage platform subdomain RskA PF10099.9 CDJ65703.1 - 0.03 14.6 0.3 0.03 14.6 0.3 10.5 4 3 3 8 8 8 0 Anti-sigma-K factor rskA Arm PF00514.23 CDJ65703.1 - 4.6 7.4 9.5 29 4.9 0.5 4.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CH_2 PF06294.11 CDJ65705.1 - 2.9e-31 107.4 0.1 6.7e-31 106.3 0.0 1.6 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CDJ65705.1 - 2.9e-10 39.8 0.0 4.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 CAMSAP CH domain DUF3972 PF13118.6 CDJ65705.1 - 0.068 13.6 7.7 0.31 11.5 7.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) DDHD PF02862.17 CDJ65706.1 - 0.015 15.5 3.2 0.019 15.1 3.2 1.3 1 0 0 1 1 1 0 DDHD domain Ndc1_Nup PF09531.10 CDJ65706.1 - 0.12 11.1 9.7 0.0089 14.8 3.0 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SpoIIP PF07454.11 CDJ65706.1 - 0.25 10.8 12.3 0.34 10.3 12.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AGTRAP PF06396.11 CDJ65706.1 - 0.29 10.9 0.0 0.29 10.9 0.0 2.5 2 0 0 2 2 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Pex14_N PF04695.13 CDJ65706.1 - 0.32 11.6 21.1 0.56 10.8 21.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4471 PF14740.6 CDJ65706.1 - 0.67 9.1 6.0 2.7 7.1 7.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) TFIIA PF03153.13 CDJ65706.1 - 0.83 9.6 34.4 1 9.3 34.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YjbH PF06082.11 CDJ65706.1 - 1.7 7.3 8.6 2.2 7.0 8.6 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH PAT1 PF09770.9 CDJ65706.1 - 3.1 6.0 24.1 3.7 5.7 24.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EFTUD2 PF16004.5 CDJ65706.1 - 3.1 8.4 17.3 5.8 7.5 17.3 1.4 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus ATP11 PF06644.11 CDJ65706.1 - 5.7 6.7 17.0 9.9 5.9 17.0 1.3 1 0 0 1 1 1 0 ATP11 protein ADD_DNMT3 PF17980.1 CDJ65707.1 - 0.6 10.1 2.7 4.2 7.4 0.7 2.2 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 SID-1_RNA_chan PF13965.6 CDJ65707.1 - 2 6.7 4.6 3.1 6.1 4.6 1.3 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 CSG2 PF16965.5 CDJ65707.1 - 7.7 5.3 6.6 3.3 6.6 4.5 1.4 1 1 0 1 1 1 0 Ceramide synthase regulator hEGF PF12661.7 CDJ65708.1 - 8.3e-08 32.6 39.9 0.015 15.9 1.5 6.3 5 0 0 5 5 5 4 Human growth factor-like EGF EGF PF00008.27 CDJ65708.1 - 0.00055 20.2 5.8 0.00055 20.2 5.8 6.4 6 0 0 6 6 5 4 EGF-like domain cEGF PF12662.7 CDJ65708.1 - 0.0014 18.5 10.9 0.0088 16.0 0.5 6.1 7 0 0 7 7 6 4 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDJ65708.1 - 0.0081 16.4 4.8 0.0081 16.4 4.8 7.5 5 1 1 6 6 5 3 Coagulation Factor Xa inhibitory site TFIIA PF03153.13 CDJ65708.1 - 0.023 14.7 46.0 0.066 13.2 46.0 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EGF_3 PF12947.7 CDJ65708.1 - 0.026 14.7 3.2 0.026 14.7 3.2 5.8 5 0 0 5 5 5 0 EGF domain Med15 PF09606.10 CDJ65708.1 - 1.3 7.6 40.6 2.4 6.7 40.6 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SID-1_RNA_chan PF13965.6 CDJ65708.1 - 1.4 7.2 3.5 2 6.7 3.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Otopetrin PF03189.13 CDJ65708.1 - 1.7 7.4 4.8 3 6.6 4.8 1.5 1 0 0 1 1 1 0 Otopetrin RR_TM4-6 PF06459.12 CDJ65708.1 - 2.2 8.0 22.3 3.5 7.4 22.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ65708.1 - 3.7 7.5 18.0 0.59 10.1 14.0 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CENP-N PF05238.13 CDJ65708.1 - 4.9 6.3 16.4 7.7 5.7 16.4 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Asp-B-Hydro_N PF05279.11 CDJ65708.1 - 6.6 6.7 18.3 9.5 6.2 18.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region EGF_3 PF12947.7 CDJ65709.1 - 0.0043 17.2 5.3 0.0043 17.2 5.3 5.6 5 0 0 5 5 5 3 EGF domain DUF812 PF05667.11 CDJ65709.1 - 0.0088 15.0 0.0 0.0088 15.0 0.0 6.5 5 3 0 5 5 5 2 Protein of unknown function (DUF812) FXa_inhibition PF14670.6 CDJ65709.1 - 1.9 8.9 56.4 0.65 10.3 2.3 6.0 5 0 0 5 5 5 0 Coagulation Factor Xa inhibitory site ATF7IP_BD PF16788.5 CDJ65710.1 - 0.19 11.8 5.7 0.23 11.5 5.7 1.1 1 0 0 1 1 1 0 ATF-interacting protein binding domain Presenilin PF01080.17 CDJ65710.1 - 0.5 9.1 4.3 0.56 8.9 4.3 1.0 1 0 0 1 1 1 0 Presenilin BAF1_ABF1 PF04684.13 CDJ65710.1 - 0.57 9.2 9.6 0.64 9.0 9.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDC27 PF09507.10 CDJ65710.1 - 1.5 8.1 12.0 1.7 7.9 12.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FSA_C PF10479.9 CDJ65710.1 - 3 5.8 12.5 3.3 5.7 12.5 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus IMUP PF15761.5 CDJ65712.1 - 0.0064 17.2 5.2 0.0064 17.2 5.2 6.0 5 1 1 6 6 6 1 Immortalisation up-regulated protein DUF4366 PF14283.6 CDJ65712.1 - 0.0072 16.4 0.7 0.0072 16.4 0.7 6.3 3 2 3 6 6 6 1 Domain of unknown function (DUF4366) DUF2232 PF09991.9 CDJ65712.1 - 9 5.4 5.2 31 3.6 0.3 2.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) 2OG-FeII_Oxy_2 PF13532.6 CDJ65714.1 - 1.1e-20 74.6 3.2 1.1e-20 74.6 3.2 4.6 4 1 1 5 5 5 1 2OG-Fe(II) oxygenase superfamily CDK2AP PF09806.9 CDJ65714.1 - 0.0086 16.2 21.2 0.0086 16.2 21.2 5.9 4 1 1 5 5 5 1 Cyclin-dependent kinase 2-associated protein RCC1 PF00415.18 CDJ65715.1 - 1.4e-16 60.8 14.1 4.4e-08 33.6 0.1 4.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat SID-1_RNA_chan PF13965.6 CDJ65715.1 - 0.0033 15.9 1.9 0.0033 15.9 1.9 3.3 3 0 0 3 3 3 2 dsRNA-gated channel SID-1 EF_TS PF00889.19 CDJ65717.1 - 2.7e-24 85.9 18.6 8.9e-22 77.7 2.7 3.9 3 2 0 3 3 3 2 Elongation factor TS Macoilin PF09726.9 CDJ65717.1 - 0.00043 19.0 15.8 0.00043 19.0 15.8 2.8 3 1 0 3 3 3 1 Macoilin family Spt20 PF12090.8 CDJ65717.1 - 0.0083 15.8 16.6 0.0083 15.8 16.6 2.4 3 0 0 3 3 3 1 Spt20 family RHH_1 PF01402.21 CDJ65717.1 - 0.081 12.9 0.1 1.9 8.5 0.1 2.8 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Terminase_4 PF05119.12 CDJ65717.1 - 0.12 12.9 5.2 0.17 12.3 0.3 2.7 2 0 0 2 2 2 0 Phage terminase, small subunit zf-C2H2_10 PF16588.5 CDJ65717.1 - 0.14 11.9 0.5 0.33 10.7 0.5 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger DUF5519 PF17648.1 CDJ65717.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5519) RskA PF10099.9 CDJ65718.1 - 0.018 15.3 24.4 0.026 14.8 24.4 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Dehydrin PF00257.19 CDJ65718.1 - 0.026 15.1 3.6 0.035 14.7 3.6 1.1 1 0 0 1 1 1 0 Dehydrin TFIIA PF03153.13 CDJ65718.1 - 0.16 12.0 19.8 0.17 11.9 19.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ65718.1 - 0.22 12.5 2.7 0.24 12.4 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM199X PF15814.5 CDJ65718.1 - 0.27 10.3 8.5 0.33 10.0 8.5 1.0 1 0 0 1 1 1 0 Protein family FAM199X CPSF100_C PF13299.6 CDJ65718.1 - 0.34 11.1 3.9 0.39 10.9 3.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FHIPEP PF00771.20 CDJ65718.1 - 0.52 8.7 3.2 0.59 8.5 3.2 1.0 1 0 0 1 1 1 0 FHIPEP family Spt20 PF12090.8 CDJ65718.1 - 0.57 9.7 15.8 0.64 9.6 15.8 1.1 1 0 0 1 1 1 0 Spt20 family YdjM PF04307.14 CDJ65718.1 - 0.96 8.7 3.5 1.1 8.5 3.5 1.1 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase DUF2722 PF10846.8 CDJ65718.1 - 1.2 8.0 15.5 1.6 7.6 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Zea_mays_MuDR PF05928.11 CDJ65718.1 - 3.8 7.1 5.6 3.7 7.1 5.6 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Presenilin PF01080.17 CDJ65718.1 - 4.3 6.0 5.8 4.7 5.9 5.8 1.1 1 0 0 1 1 1 0 Presenilin RabGAP-TBC PF00566.18 CDJ65719.1 - 3.6e-19 69.3 0.0 4.7e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cytochrom_B_N_2 PF13631.6 CDJ65720.1 - 0.017 15.1 0.2 0.021 14.9 0.2 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB SARAF PF06682.12 CDJ65720.1 - 0.034 13.8 0.0 0.036 13.7 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DDE_Tnp_1_6 PF13751.6 CDJ65721.1 - 0.00089 19.5 5.2 0.0019 18.4 5.2 1.4 1 0 0 1 1 1 1 Transposase DDE domain Macoilin PF09726.9 CDJ65721.1 - 0.0046 15.6 11.3 0.0066 15.1 11.3 1.1 1 0 0 1 1 1 1 Macoilin family BUD22 PF09073.10 CDJ65721.1 - 4.6 6.5 12.6 2.5 7.3 1.4 2.2 2 0 0 2 2 2 0 BUD22 DUF3446 PF11928.8 CDJ65721.1 - 5.8 7.3 19.7 0.084 13.2 11.6 2.2 3 0 0 3 3 3 0 Early growth response N-terminal domain IMUP PF15761.5 CDJ65721.1 - 6 7.6 16.0 17 6.2 16.0 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF508 PF04370.12 CDJ65721.1 - 8.8 6.1 8.5 17 5.1 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Ribosomal_L1 PF00687.21 CDJ65722.1 - 1.5e-41 142.4 4.2 1.8e-41 142.1 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_S24e PF01282.19 CDJ65723.1 - 6.4e-23 80.5 0.0 9.1e-23 80.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e SpoIIIAH PF12685.7 CDJ65725.1 - 0.0036 17.1 7.5 0.0059 16.5 7.5 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein SUIM_assoc PF16619.5 CDJ65725.1 - 0.021 14.9 2.7 0.021 14.9 2.7 3.4 2 1 0 2 2 1 0 Unstructured region C-term to UIM in Ataxin3 DUF719 PF05334.13 CDJ65725.1 - 0.1 12.8 10.5 0.081 13.1 6.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Spt20 PF12090.8 CDJ65725.1 - 0.19 11.3 45.8 0.33 10.5 32.0 2.1 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ65725.1 - 0.23 11.0 12.9 0.061 12.9 9.9 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SMC_hinge PF06470.13 CDJ65725.1 - 0.52 10.6 9.0 0.049 14.0 3.9 1.8 1 1 1 2 2 2 0 SMC proteins Flexible Hinge Domain Sec62 PF03839.16 CDJ65725.1 - 0.58 9.6 3.5 0.6 9.6 1.7 1.7 2 0 0 2 2 2 0 Translocation protein Sec62 ANAPC_CDC26 PF10471.9 CDJ65725.1 - 1.2 10.0 37.9 6.3 7.7 25.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF2722 PF10846.8 CDJ65725.1 - 1.6 7.6 36.3 0.49 9.3 24.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4770 PF15994.5 CDJ65725.1 - 1.9 8.7 11.3 1.5 9.0 7.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF3371 PF11851.8 CDJ65725.1 - 2.3 9.4 19.6 1.6 9.8 11.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) MMR1 PF08505.10 CDJ65725.1 - 3.3 7.9 19.1 2 8.6 13.9 2.0 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Miga PF10265.9 CDJ65725.1 - 3.8 6.4 11.6 8.2 5.3 11.8 1.4 1 1 0 1 1 1 0 Mitoguardin Peptidase_S49_N PF08496.10 CDJ65725.1 - 5.4 7.1 10.9 29 4.7 0.1 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Podoplanin PF05808.11 CDJ65725.1 - 5.7 7.0 6.3 2.2 8.4 2.8 1.8 2 0 0 2 2 2 0 Podoplanin NST1 PF13945.6 CDJ65725.1 - 6.7 6.8 18.5 0.23 11.6 8.0 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF4834 PF16118.5 CDJ65725.1 - 7.2 7.6 18.3 33 5.5 13.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SR-25 PF10500.9 CDJ65726.1 - 7.3e-05 22.5 10.6 7.3e-05 22.5 10.6 6.8 5 1 2 7 7 7 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ65726.1 - 0.00041 20.7 9.2 0.00041 20.7 9.2 12.1 2 1 5 8 8 8 1 Anti-sigma-K factor rskA N6_N4_Mtase PF01555.18 CDJ65726.1 - 0.058 13.1 1.1 11 5.7 0.0 4.0 2 2 0 2 2 2 0 DNA methylase RPN7 PF10602.9 CDJ65727.1 - 1.6e-33 115.9 3.2 3.8e-31 108.1 0.1 2.1 1 1 1 2 2 2 2 26S proteasome subunit RPN7 RNA_pol_A_bac PF01000.26 CDJ65728.1 - 1.5e-10 41.4 0.0 3.5e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CDJ65728.1 - 2.6e-10 39.6 0.0 4.7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CtsR_C PF17727.1 CDJ65728.1 - 0.12 12.5 2.3 0.37 10.9 0.1 2.3 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain Peptidase_S49_N PF08496.10 CDJ65728.1 - 0.54 10.3 7.0 0.16 12.1 3.5 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Spt20 PF12090.8 CDJ65728.1 - 2.5 7.7 31.0 0.077 12.6 13.6 3.3 3 0 0 3 3 3 0 Spt20 family DUF5345 PF17280.2 CDJ65729.1 - 0.015 15.2 1.7 0.029 14.3 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5345) CYSTM PF12734.7 CDJ65729.1 - 0.5 10.7 9.4 0.82 10.0 8.5 1.9 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Spt20 PF12090.8 CDJ65729.1 - 1.6 8.2 4.9 0.19 11.3 0.9 1.5 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ65730.1 - 2.5 8.0 11.3 3 7.7 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3446 PF11928.8 CDJ65730.1 - 9 6.7 52.4 1.5 9.2 13.7 3.3 3 0 0 3 3 3 0 Early growth response N-terminal domain ASCH PF04266.14 CDJ65732.1 - 3.6e-06 27.5 0.0 5.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 ASCH domain DUF4667 PF15700.5 CDJ65732.1 - 0.00039 20.6 0.0 0.00067 19.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4667) DUF2722 PF10846.8 CDJ65732.1 - 0.0014 17.7 1.4 0.0014 17.7 1.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF3446 PF11928.8 CDJ65732.1 - 0.59 10.5 14.0 0.39 11.0 11.5 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain IMUP PF15761.5 CDJ65732.1 - 4 8.2 10.9 13 6.6 10.9 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein Aha1_N PF09229.11 CDJ65733.1 - 1.3e-12 48.1 0.0 5.8e-11 42.8 0.0 2.3 1 1 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TMEM51 PF15345.6 CDJ65733.1 - 3.5 7.4 9.2 0.96 9.2 0.6 2.6 2 0 0 2 2 2 0 Transmembrane protein 51 Chromo PF00385.24 CDJ65734.1 - 1.2e-13 50.7 0.0 2.2e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 CDJ65734.1 - 2.1e-13 50.2 1.6 5.2e-13 48.9 1.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Pribosyltran PF00156.27 CDJ65736.1 - 3.6e-20 72.1 0.0 4.7e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 CDJ65736.1 - 0.046 13.2 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase CTP_transf_like PF01467.26 CDJ65737.1 - 1.1e-31 109.9 0.1 2e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Myosin_head PF00063.21 CDJ65738.1 - 1.3e-37 129.4 0.0 2.1e-18 65.9 0.0 2.4 1 1 1 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 CDJ65738.1 - 4.2e-17 60.3 33.7 4.4e-05 22.9 0.6 7.4 7 0 0 7 7 7 5 IQ calmodulin-binding motif SprA-related PF12118.8 CDJ65740.1 - 0.00036 19.8 21.7 0.00047 19.4 21.7 1.2 1 0 0 1 1 1 1 SprA-related family TFIIA PF03153.13 CDJ65740.1 - 0.00077 19.6 29.3 0.00089 19.4 29.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 CDJ65740.1 - 0.011 15.3 9.9 0.013 15.2 9.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rrn6 PF10214.9 CDJ65740.1 - 0.047 12.2 21.2 0.061 11.8 21.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor GET2 PF08690.10 CDJ65740.1 - 0.11 12.2 15.1 0.13 11.9 15.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 PDCD7 PF16021.5 CDJ65740.1 - 0.16 11.1 16.7 0.21 10.7 16.7 1.1 1 0 0 1 1 1 0 Programmed cell death protein 7 PPP4R2 PF09184.11 CDJ65740.1 - 0.19 11.3 9.2 0.24 10.9 9.2 1.2 1 0 0 1 1 1 0 PPP4R2 eIF-3_zeta PF05091.12 CDJ65740.1 - 0.49 9.3 17.5 0.57 9.1 17.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) U1snRNP70_N PF12220.8 CDJ65740.1 - 0.63 10.7 12.0 1.2 9.8 12.0 1.5 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DREPP PF05558.12 CDJ65740.1 - 0.97 9.3 4.7 1.4 8.8 4.7 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide PAT1 PF09770.9 CDJ65740.1 - 1.2 7.3 25.8 1.4 7.1 25.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.14 CDJ65740.1 - 1.4 8.8 21.0 2.2 8.2 21.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LMBR1 PF04791.16 CDJ65740.1 - 2 7.2 10.7 2.5 6.9 10.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 CDJ65740.1 - 2.9 7.2 22.7 3.6 6.9 22.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Activator_LAG-3 PF11498.8 CDJ65740.1 - 3.4 6.5 40.5 5 6.0 40.5 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HCO3_cotransp PF00955.21 CDJ65740.1 - 5.3 5.7 7.6 6.6 5.4 7.6 1.1 1 0 0 1 1 1 0 HCO3- transporter family Connexin PF00029.19 CDJ65740.1 - 5.7 6.6 10.7 7.6 6.2 10.7 1.2 1 0 0 1 1 1 0 Connexin DDHD PF02862.17 CDJ65740.1 - 8.7 6.4 22.0 1e+02 3.0 22.0 2.1 1 1 0 1 1 1 0 DDHD domain Nucleoside_tran PF01733.18 CDJ65741.1 - 1.2e-08 34.7 1.5 3.2e-05 23.5 1.6 2.6 2 0 0 2 2 2 2 Nucleoside transporter DUF4407 PF14362.6 CDJ65741.1 - 0.00012 21.6 0.8 0.00012 21.6 0.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) Sdh_cyt PF01127.22 CDJ65741.1 - 0.0017 18.4 3.7 0.0053 16.8 1.3 2.8 3 0 0 3 3 3 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TMEM208_SND2 PF05620.11 CDJ65741.1 - 0.022 14.5 0.9 0.022 14.5 0.9 4.2 5 0 0 5 5 5 0 SRP-independent targeting protein 2/TMEM208 DUF1980 PF09323.10 CDJ65741.1 - 0.47 10.4 4.4 22 4.9 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1980) TFIIA PF03153.13 CDJ65741.1 - 2.3 8.1 38.8 0.47 10.4 3.6 3.0 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ65741.1 - 2.4 9.2 0.0 2.4 9.2 0.0 3.9 4 2 0 4 4 4 0 Domain of unknown function (DUF4834) DUF1180 PF06679.12 CDJ65744.1 - 0.0054 17.2 1.1 0.0054 17.2 1.1 4.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1180) DUF1180 PF06679.12 CDJ65745.1 - 0.0054 17.2 1.1 0.0054 17.2 1.1 4.2 4 1 1 5 5 5 1 Protein of unknown function (DUF1180) DUF3408 PF11888.8 CDJ65746.1 - 1.2e-11 44.9 1.4 0.0056 16.8 0.0 6.0 6 0 0 6 6 6 3 Protein of unknown function (DUF3408) DUF2163 PF09931.9 CDJ65746.1 - 0.012 15.9 3.8 2.6 8.2 0.0 5.0 3 2 2 5 5 5 0 Uncharacterized conserved protein (DUF2163) Fe_dep_repr_C PF02742.15 CDJ65746.1 - 0.067 13.3 12.4 26 5.0 0.3 6.6 7 1 1 8 8 8 0 Iron dependent repressor, metal binding and dimerisation domain Chlorophyllase PF07224.11 CDJ65746.1 - 4.3 6.3 14.2 0.51 9.3 0.1 5.4 8 0 0 8 8 8 0 Chlorophyllase UCH PF00443.29 CDJ65746.1 - 9.5 5.6 7.1 6 6.3 0.8 2.7 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase PAM2 PF07145.15 CDJ65747.1 - 0.0012 18.4 1.7 0.0027 17.3 1.7 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Nucleoside_tran PF01733.18 CDJ65749.1 - 7.3e-12 45.3 2.8 7.3e-12 45.3 2.8 1.8 2 0 0 2 2 2 1 Nucleoside transporter Hanta_nucleocap PF00846.18 CDJ65749.1 - 0.19 10.1 0.2 0.28 9.6 0.2 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein Spt20 PF12090.8 CDJ65749.1 - 0.48 10.0 5.4 1 8.9 5.4 1.5 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ65750.1 - 0.023 14.7 16.6 0.026 14.5 16.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ65750.1 - 0.73 9.7 8.7 0.74 9.7 8.7 1.1 1 0 0 1 1 1 0 SPX domain Lin-8 PF03353.15 CDJ65750.1 - 2.1 7.8 8.4 2.6 7.5 8.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CDJ65750.1 - 2.4 7.7 20.6 3.1 7.4 20.6 1.2 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 CDJ65750.1 - 4.9 5.3 13.9 5.3 5.2 13.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ65750.1 - 9.6 3.2 7.3 9.8 3.1 7.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer VID27 PF08553.10 CDJ65751.1 - 4.7e-33 114.7 0.0 7.4e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain DUF2722 PF10846.8 CDJ65751.1 - 1.6e-05 24.1 4.6 1.6e-05 24.1 4.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Med3 PF11593.8 CDJ65751.1 - 0.0016 17.7 15.3 0.0016 17.7 15.3 2.3 2 0 0 2 2 1 1 Mediator complex subunit 3 fungal Spt20 PF12090.8 CDJ65751.1 - 0.0019 17.9 14.4 0.0037 16.9 14.4 1.4 1 0 0 1 1 1 1 Spt20 family EOS1 PF12326.8 CDJ65751.1 - 0.11 12.4 1.6 0.31 11.0 1.6 1.8 1 1 0 1 1 1 0 N-glycosylation protein DUF4578 PF15147.6 CDJ65751.1 - 0.16 12.8 10.4 0.092 13.6 7.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) FlaG PF03646.15 CDJ65751.1 - 0.42 10.8 12.2 1.2 9.4 12.2 1.8 1 0 0 1 1 1 0 FlaG protein SR-25 PF10500.9 CDJ65751.1 - 0.59 9.7 44.7 0.57 9.8 13.4 3.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ65751.1 - 0.63 10.0 35.3 1.4 8.8 34.8 1.8 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FHIPEP PF00771.20 CDJ65751.1 - 0.74 8.2 2.7 1.3 7.4 2.7 1.3 1 0 0 1 1 1 0 FHIPEP family EPL1 PF10513.9 CDJ65751.1 - 0.83 10.0 8.4 2.5 8.5 4.0 2.9 3 0 0 3 3 3 0 Enhancer of polycomb-like EIIBC-GUT_N PF03612.14 CDJ65751.1 - 0.95 9.2 4.2 2.1 8.0 4.2 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AIF_C PF14721.6 CDJ65751.1 - 1.2 9.5 3.7 5.3 7.4 3.7 2.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RR_TM4-6 PF06459.12 CDJ65751.1 - 2.8 7.7 8.4 7.2 6.3 6.7 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Peptidase_C13 PF01650.18 CDJ65752.1 - 9.5e-27 94.1 0.1 4.5e-20 72.3 0.0 4.0 3 1 1 4 4 3 2 Peptidase C13 family Velvet PF11754.8 CDJ65752.1 - 2.7e-06 27.5 24.6 0.0015 18.6 6.3 3.4 3 0 0 3 3 3 2 Velvet factor SARAF PF06682.12 CDJ65752.1 - 3.1e-05 23.8 4.4 3.1e-05 23.8 4.4 3.2 3 0 0 3 3 3 2 SOCE-associated regulatory factor of calcium homoeostasis SpoIIP PF07454.11 CDJ65752.1 - 0.00057 19.4 9.2 0.00057 19.4 9.2 3.9 3 1 0 3 3 2 1 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CDJ65752.1 - 0.0014 17.5 36.7 0.016 14.0 13.4 3.1 3 0 0 3 3 3 2 Presenilin EPL1 PF10513.9 CDJ65752.1 - 0.0046 17.3 7.6 0.0046 17.3 7.6 3.9 3 1 0 3 3 2 1 Enhancer of polycomb-like Peptidase_U57 PF05582.12 CDJ65752.1 - 0.0062 15.8 9.3 0.0062 15.8 9.3 3.2 3 1 0 3 3 2 1 YabG peptidase U57 CCSAP PF15748.5 CDJ65752.1 - 0.013 15.7 37.3 0.042 14.0 11.1 3.2 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated ABC2_membrane_2 PF12679.7 CDJ65752.1 - 0.017 14.4 11.6 0.11 11.7 1.2 3.7 3 1 0 3 3 3 0 ABC-2 family transporter protein BAT2_N PF07001.11 CDJ65752.1 - 0.019 15.4 14.8 0.019 15.4 14.8 3.9 3 1 0 3 3 3 0 BAT2 N-terminus NPR3 PF03666.13 CDJ65752.1 - 0.031 13.1 23.7 0.028 13.2 6.9 3.0 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 Ndc1_Nup PF09531.10 CDJ65752.1 - 0.06 12.0 36.8 0.003 16.3 4.0 3.2 3 0 0 3 3 3 0 Nucleoporin protein Ndc1-Nup PIP5K PF01504.18 CDJ65752.1 - 0.17 11.1 28.6 0.13 11.5 9.0 3.6 3 1 0 3 3 3 0 Phosphatidylinositol-4-phosphate 5-Kinase SAGA-Tad1 PF12767.7 CDJ65752.1 - 0.25 11.0 30.6 0.21 11.3 7.8 3.2 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2052 PF09747.9 CDJ65752.1 - 0.62 10.2 41.1 0.022 14.9 9.8 3.7 4 0 0 4 4 4 0 Coiled-coil domain containing protein (DUF2052) Zip PF02535.22 CDJ65752.1 - 0.79 8.9 14.6 0.45 9.7 2.7 3.0 3 0 0 3 3 3 0 ZIP Zinc transporter DUF3295 PF11702.8 CDJ65752.1 - 0.82 8.9 37.1 0.57 9.5 11.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3295) DUF4050 PF13259.6 CDJ65752.1 - 1.2 9.5 30.4 1.1 9.6 9.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) DUF4045 PF13254.6 CDJ65752.1 - 1.9 8.0 31.1 0.066 12.9 5.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4045) DUF3807 PF12720.7 CDJ65752.1 - 2.2 8.5 51.9 0.067 13.5 17.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) TRAP_alpha PF03896.16 CDJ65752.1 - 2.8 7.1 15.5 0.38 9.9 2.7 2.8 3 1 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit DUF913 PF06025.12 CDJ65752.1 - 3.6 6.5 21.9 0.068 12.1 4.1 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Striatin PF08232.12 CDJ65752.1 - 3.7 8.1 43.6 0.035 14.7 9.4 3.3 3 0 0 3 3 3 0 Striatin family DAG_kinase_N PF14513.6 CDJ65752.1 - 3.8 7.7 32.4 0.17 12.0 8.0 3.5 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus CLN3 PF02487.17 CDJ65752.1 - 3.9 6.4 27.0 2.9 6.8 2.4 3.3 3 0 0 3 3 3 0 CLN3 protein Endostatin PF06482.11 CDJ65752.1 - 4.6 6.6 36.2 6.3 6.2 13.9 3.3 3 0 0 3 3 3 0 Collagenase NC10 and Endostatin AAA_11 PF13086.6 CDJ65752.1 - 6.4 6.5 31.6 0.044 13.6 6.9 3.4 3 0 0 3 3 3 0 AAA domain LAP1C PF05609.12 CDJ65752.1 - 7.7 5.5 35.5 0.6 9.1 10.0 3.2 3 0 0 3 3 3 0 Lamina-associated polypeptide 1C (LAP1C) DUF2370 PF10176.9 CDJ65752.1 - 8.4 6.0 20.0 4.7 6.8 1.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2370) CNDH2_C PF16858.5 CDJ65752.1 - 9.3 6.0 41.7 0.024 14.5 9.7 3.2 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2722 PF10846.8 CDJ65753.1 - 0.00046 19.3 1.8 0.00046 19.3 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ65753.1 - 0.00063 19.4 4.5 0.00063 19.4 4.5 1.1 1 0 0 1 1 1 1 Spt20 family Activator_LAG-3 PF11498.8 CDJ65753.1 - 1.4 7.8 15.0 1.6 7.6 15.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pex14_N PF04695.13 CDJ65753.1 - 1.8 9.2 12.6 8.8 7.0 12.6 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM247 PF15444.6 CDJ65753.1 - 2 8.4 6.0 2.7 8.0 6.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 zf-RING_2 PF13639.6 CDJ65754.1 - 2e-09 37.7 15.1 2e-09 37.7 15.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CDJ65754.1 - 4.9e-07 29.4 6.4 4.9e-07 29.4 6.4 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDJ65754.1 - 1.1e-06 28.4 13.7 1.1e-06 28.4 13.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ65754.1 - 3.9e-05 23.6 7.5 3.9e-05 23.6 7.5 3.2 3 1 1 4 4 4 1 RING-type zinc-finger zf-rbx1 PF12678.7 CDJ65754.1 - 4.1e-05 23.8 12.3 4.1e-05 23.8 12.3 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ65754.1 - 0.00017 21.4 14.0 0.00017 21.4 14.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ65754.1 - 0.0067 16.4 14.3 0.0067 16.4 14.3 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CDJ65754.1 - 0.84 9.7 9.0 0.26 11.4 4.8 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Telomere_Sde2_2 PF13297.6 CDJ65755.1 - 0.051 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Telomere stability C-terminal TIM PF00121.18 CDJ65756.1 - 6.9e-47 159.9 0.0 3.6e-24 85.5 0.2 2.1 1 1 1 2 2 2 2 Triosephosphate isomerase Lsr2 PF11774.8 CDJ65756.1 - 1.7 8.8 4.2 0.85 9.8 0.4 2.0 2 0 0 2 2 2 0 Lsr2 MT-A70 PF05063.14 CDJ65757.1 - 1.7e-57 194.1 0.4 1.7e-57 194.1 0.4 2.6 3 0 0 3 3 3 1 MT-A70 LRR_4 PF12799.7 CDJ65758.1 - 4.3e-14 52.4 13.9 0.00046 20.5 1.4 5.0 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ65758.1 - 6.2e-09 35.5 11.4 0.00014 21.5 0.1 4.5 4 0 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 CDJ65758.1 - 0.95 10.3 14.6 2.8 8.8 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat Ank_2 PF12796.7 CDJ65759.1 - 1.4e-21 76.9 0.0 1.5e-13 51.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DHHC PF01529.20 CDJ65759.1 - 5e-15 55.8 2.1 5e-15 55.8 2.1 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 CDJ65759.1 - 1.4e-11 44.6 2.9 8.4e-06 26.2 0.3 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ65759.1 - 2.6e-11 42.7 3.2 3.1e-06 27.1 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CDJ65759.1 - 3.2e-10 40.0 1.9 4.1e-07 30.1 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CDJ65759.1 - 3.2e-09 36.9 0.1 9.1e-07 29.0 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF3446 PF11928.8 CDJ65759.1 - 0.99 9.8 19.4 0.71 10.2 6.1 2.9 2 0 0 2 2 2 0 Early growth response N-terminal domain MpPF26 PF07666.11 CDJ65759.1 - 2.8 8.0 9.7 0.13 12.3 3.4 1.9 2 0 0 2 2 2 0 M penetrans paralogue family 26 Ribosomal_L19 PF01245.20 CDJ65760.1 - 9.2e-13 48.1 0.0 1.8e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 TFIIA PF03153.13 CDJ65760.1 - 2.7 7.9 5.2 3.8 7.4 5.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Alpha-amylase PF00128.24 CDJ65763.1 - 4.8e-17 62.5 0.0 6.8e-10 39.0 0.0 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amyl_C2 PF07821.12 CDJ65763.1 - 3.8e-13 49.4 0.5 8.7e-13 48.3 0.5 1.6 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain fn3 PF00041.21 CDJ65763.1 - 4.1e-05 23.8 0.1 0.0005 20.4 0.0 2.9 3 1 0 3 3 3 1 Fibronectin type III domain Macoilin PF09726.9 CDJ65763.1 - 2.9 6.3 17.9 0.024 13.2 8.7 1.9 2 0 0 2 2 2 0 Macoilin family Calpain_III PF01067.22 CDJ65764.1 - 0.025 14.9 0.1 11 6.3 0.0 4.1 5 0 0 5 5 5 0 Calpain large subunit, domain III Peptidase_C2 PF00648.21 CDJ65765.1 - 2.5e-05 23.5 0.1 0.0024 17.0 0.0 3.0 2 1 0 2 2 2 1 Calpain family cysteine protease PhyH PF05721.13 CDJ65767.1 - 0.00025 21.4 0.3 0.079 13.2 0.0 2.7 2 1 1 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 CDJ65767.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family Cullin PF00888.22 CDJ65768.1 - 3.1e-134 448.9 10.1 4.4e-134 448.4 10.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ65768.1 - 2e-22 79.0 0.2 9.8e-22 76.8 0.2 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF4449 PF14613.6 CDJ65768.1 - 0.037 14.1 5.6 13 5.8 0.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4449) DUF445 PF04286.12 CDJ65768.1 - 0.17 11.6 8.3 0.11 12.3 1.3 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF445) PKD_channel PF08016.12 CDJ65769.1 - 7.8e-10 38.0 13.6 1.8e-09 36.8 13.6 1.6 1 0 0 1 1 1 1 Polycystin cation channel Nsp2a_N PF17896.1 CDJ65769.1 - 0.22 10.7 3.8 0.35 10.0 3.8 1.2 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain Ion_trans PF00520.31 CDJ65770.1 - 0.11 11.7 20.8 0.42 9.8 17.6 2.7 2 1 0 2 2 2 0 Ion transport protein PKD_channel PF08016.12 CDJ65770.1 - 2.8 6.5 24.3 0.0089 14.7 9.6 2.8 3 0 0 3 3 3 0 Polycystin cation channel SRTM1 PF15872.5 CDJ65771.1 - 0.1 12.8 0.1 0.1 12.8 0.1 1.9 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 PKD_channel PF08016.12 CDJ65772.1 - 2.3e-09 36.4 12.2 2.3e-09 36.4 12.2 2.7 3 0 0 3 3 3 1 Polycystin cation channel Ion_trans PF00520.31 CDJ65772.1 - 0.0038 16.5 16.1 0.0038 16.5 16.1 2.5 3 0 0 3 3 3 1 Ion transport protein Kinesin PF00225.23 CDJ65773.1 - 5.2e-86 288.6 0.0 1.7e-43 148.9 0.1 2.4 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ65773.1 - 3.3e-21 75.8 0.1 1.1e-20 74.1 0.1 1.9 1 1 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 CDJ65773.1 - 9.7e-06 25.8 10.1 0.0014 18.8 0.3 3.5 2 2 2 4 4 4 2 Kinesin-associated KIF1B PF12423.8 CDJ65773.1 - 0.00023 21.5 0.1 0.0023 18.3 0.0 2.6 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.26 CDJ65773.1 - 0.087 13.2 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 FHA domain DinB PF05163.12 CDJ65773.1 - 2.7 7.9 7.2 8.9 6.2 2.1 2.7 2 0 0 2 2 2 0 DinB family Retrotrans_gag PF03732.17 CDJ65774.1 - 0.0044 17.3 0.0 0.0052 17.0 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein RT_RNaseH PF17917.1 CDJ65775.1 - 3.8e-16 59.3 0.0 9e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ65775.1 - 1.4e-12 47.6 1.0 3e-12 46.5 1.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CDJ65775.1 - 1.4e-09 37.9 0.0 3.6e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ65775.1 - 5.4e-05 23.4 0.0 0.00022 21.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 CDJ65775.1 - 0.00078 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3552 PF12072.8 CDJ65775.1 - 0.011 15.1 0.2 0.017 14.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) zf-RVT PF13966.6 CDJ65776.1 - 8.4e-07 29.6 1.1 3.4e-06 27.7 1.1 2.0 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase TFIID-18kDa PF02269.16 CDJ65776.1 - 0.11 12.5 0.0 18 5.5 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit DUF45 PF01863.17 CDJ65777.1 - 0.007 16.4 0.0 0.007 16.4 0.0 3.5 4 0 0 4 4 4 1 Protein of unknown function DUF45 Metal_CEHH PF14455.6 CDJ65777.1 - 0.01 15.4 1.6 0.021 14.4 1.6 1.4 1 0 0 1 1 1 0 Predicted metal binding domain DNA_pol_B_exo1 PF03104.19 CDJ65778.1 - 0.11 11.6 0.0 0.49 9.5 0.0 1.8 1 1 0 1 1 1 0 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CDJ65779.1 - 3.3e-32 111.8 0.0 5.4e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B PF00136.21 CDJ65780.1 - 8.1e-36 123.7 0.0 1.2e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 CDJ65780.1 - 5.7e-08 33.1 7.8 2.6e-07 31.0 4.0 2.7 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta PAM2 PF07145.15 CDJ65781.1 - 0.00011 21.6 0.5 0.00029 20.3 0.5 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Histone PF00125.24 CDJ65783.1 - 3.1e-48 163.4 0.1 3.3e-48 163.3 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CDJ65783.1 - 0.00028 21.2 0.0 0.00038 20.8 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CDJ65783.1 - 0.0003 20.9 0.1 0.00038 20.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CDJ65783.1 - 0.0041 17.4 0.0 0.0055 17.0 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CDJ65783.1 - 0.013 15.6 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RRM_1 PF00076.22 CDJ65784.1 - 3.5e-13 49.1 0.1 2.4e-12 46.5 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.27 CDJ65785.1 - 2.6e-13 50.4 0.0 3.5e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Androgen_recep PF02166.16 CDJ65785.1 - 0.0024 16.8 3.3 0.0024 16.8 3.3 11.3 9 3 2 11 11 11 1 Androgen receptor DUF1645 PF07816.11 CDJ65785.1 - 0.0074 16.9 0.8 0.0074 16.9 0.8 6.3 5 1 1 6 6 6 4 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ65785.1 - 0.031 13.9 85.4 0.089 12.4 18.6 6.4 6 0 0 6 6 6 0 Spt20 family MscS_TM PF12794.7 CDJ65785.1 - 8.2 5.2 10.1 11 4.8 0.2 3.9 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 MFS_1 PF07690.16 CDJ65786.1 - 3.8e-06 26.1 9.9 3.8e-06 26.1 9.9 3.5 3 2 0 3 3 3 1 Major Facilitator Superfamily MFS_2 PF13347.6 CDJ65786.1 - 0.012 14.2 0.6 0.012 14.2 0.6 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein SPX PF03105.19 CDJ65786.1 - 0.017 15.1 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 SPX domain CcmD PF04995.14 CDJ65786.1 - 0.024 14.7 0.4 0.024 14.7 0.4 2.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) SR-25 PF10500.9 CDJ65786.1 - 1.7 8.2 26.6 0.59 9.7 15.7 2.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Peptidase_C65 PF10275.9 CDJ65787.1 - 2.4e-52 177.8 0.6 3.2e-52 177.4 0.0 1.5 2 0 0 2 2 2 1 Peptidase C65 Otubain DUF4834 PF16118.5 CDJ65787.1 - 0.97 10.4 10.8 1.6 9.7 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Hydin_ADK PF17213.3 CDJ65787.1 - 2.9 8.1 6.8 5.6 7.2 6.8 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 CDJ65787.1 - 4.3 6.0 9.2 6.1 5.5 9.2 1.1 1 0 0 1 1 1 0 Presenilin SARAF PF06682.12 CDJ65787.1 - 5.6 6.5 9.2 8.4 5.9 9.2 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis AMPK1_CBM PF16561.5 CDJ65789.1 - 2e-09 37.5 0.0 6.2e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF2722 PF10846.8 CDJ65789.1 - 0.00023 20.2 5.2 0.00051 19.1 5.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ65789.1 - 0.0045 17.1 14.8 0.0045 17.1 14.8 2.5 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit AnfO_nitrog PF09582.10 CDJ65789.1 - 0.019 14.3 0.8 0.36 10.2 0.0 2.3 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) UPF0560 PF10577.9 CDJ65789.1 - 0.091 11.2 5.3 0.15 10.5 5.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Presenilin PF01080.17 CDJ65789.1 - 0.66 8.7 2.4 0.31 9.8 0.1 1.7 2 0 0 2 2 2 0 Presenilin PUD1_2 PF18457.1 CDJ65789.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.6 3 1 1 4 4 4 0 Up-Regulated in long-lived daf-2 CPSF100_C PF13299.6 CDJ65789.1 - 2.1 8.5 4.7 3.3 7.9 0.4 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4834 PF16118.5 CDJ65789.1 - 6.9 7.7 6.6 17 6.4 6.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AP2 PF00847.20 CDJ65790.1 - 2.6e-09 37.2 0.1 2.6e-09 37.2 0.1 2.7 3 0 0 3 3 3 1 AP2 domain Apt1 PF10351.9 CDJ65791.1 - 0.11 11.4 21.4 0.0067 15.3 5.6 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain YbaB_DNA_bd PF02575.16 CDJ65791.1 - 3.2 8.0 0.0 3.2 8.0 0.0 3.8 4 0 0 4 4 4 0 YbaB/EbfC DNA-binding family MDH PF02315.16 CDJ65792.1 - 8.1 6.6 9.6 0.27 11.3 1.8 2.5 1 1 1 2 2 2 0 Methanol dehydrogenase beta subunit TFIIA PF03153.13 CDJ65792.1 - 9.6 6.1 9.7 13 5.7 9.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ65793.1 - 0.00098 18.8 12.2 0.0017 18.0 12.2 1.4 1 0 0 1 1 1 1 Spt20 family SPX PF03105.19 CDJ65793.1 - 5.8 6.7 17.4 14 5.4 17.4 1.6 1 1 0 1 1 1 0 SPX domain LPP PF04728.13 CDJ65794.1 - 0.022 15.1 6.9 0.022 15.1 6.9 4.4 5 0 0 5 5 5 0 Lipoprotein leucine-zipper COG2 PF06148.11 CDJ65794.1 - 0.065 13.3 11.7 0.12 12.4 2.4 3.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ATP-synt_D PF01813.17 CDJ65794.1 - 0.39 10.5 5.6 0.72 9.7 0.9 3.0 3 0 0 3 3 3 0 ATP synthase subunit D COG5 PF10392.9 CDJ65794.1 - 0.91 9.7 12.6 0.29 11.3 0.3 4.6 5 0 0 5 5 5 0 Golgi transport complex subunit 5 BLOC1_2 PF10046.9 CDJ65794.1 - 2.1 8.7 10.6 2.3 8.6 1.1 3.8 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 CDJ65794.1 - 5.1 7.1 7.5 5.4 7.1 1.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) SR-25 PF10500.9 CDJ65796.1 - 0.072 12.7 12.1 0.12 12.0 9.6 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sad1_UNC PF07738.13 CDJ65797.1 - 6.9e-18 64.9 0.0 1.6e-11 44.3 0.0 3.4 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal DUF1091 PF06477.13 CDJ65797.1 - 0.035 14.6 0.1 0.065 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) DUF3328 PF11807.8 CDJ65797.1 - 0.055 13.3 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) BAF1_ABF1 PF04684.13 CDJ65797.1 - 2.7 6.9 12.7 0.18 10.8 3.6 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor FapA PF03961.13 CDJ65797.1 - 5.1 5.6 6.8 9.2 4.7 6.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A PNISR PF15996.5 CDJ65798.1 - 0.34 11.2 7.7 0.56 10.4 7.7 1.4 1 1 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF572 PF04502.13 CDJ65798.1 - 0.72 9.4 8.7 0.88 9.1 8.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SPX PF03105.19 CDJ65798.1 - 1 9.2 23.4 1.4 8.8 23.4 1.1 1 0 0 1 1 1 0 SPX domain DUF3807 PF12720.7 CDJ65798.1 - 1.1 9.5 11.5 2.9 8.1 11.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3807) SOG2 PF10428.9 CDJ65798.1 - 3.3 6.8 26.8 4 6.5 26.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SR-25 PF10500.9 CDJ65799.1 - 0.0011 18.6 9.7 0.0011 18.6 9.7 3.0 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Tmemb_9 PF05434.11 CDJ65799.1 - 0.89 9.4 0.0 0.89 9.4 0.0 4.2 3 1 0 3 3 3 0 TMEM9 RskA PF10099.9 CDJ65800.1 - 0.00014 22.3 0.3 0.00014 22.3 0.3 6.3 1 1 2 3 3 3 1 Anti-sigma-K factor rskA Hid1 PF12722.7 CDJ65800.1 - 4.5 5.3 23.6 6.5 4.7 23.6 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_U57 PF05582.12 CDJ65800.1 - 4.6 6.4 18.9 0.06 12.6 0.5 2.5 2 0 0 2 2 2 0 YabG peptidase U57 Glyco_hydro_3_C PF01915.22 CDJ65800.1 - 8.8 6.2 9.9 25 4.7 9.8 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain ORC_WH_C PF18137.1 CDJ65800.1 - 8.8 6.4 27.1 6.8 6.8 2.7 3.1 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal Ribosomal_L29 PF00831.23 CDJ65802.1 - 0.0012 18.8 4.7 0.0012 18.8 4.7 3.3 2 1 1 3 3 3 1 Ribosomal L29 protein Macoilin PF09726.9 CDJ65802.1 - 1.2 7.6 21.2 1.3 7.5 21.2 1.1 1 0 0 1 1 1 0 Macoilin family DIT1_PvcA PF05141.12 CDJ65802.1 - 1.4 8.3 8.4 2 7.8 8.4 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Tam41_Mmp37 PF09139.11 CDJ65802.1 - 2.4 7.5 14.4 3.7 6.9 14.4 1.2 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial FapA PF03961.13 CDJ65802.1 - 2.5 6.6 13.8 3.4 6.2 13.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HBS1_N PF08938.10 CDJ65802.1 - 6.6 7.1 10.1 16 5.9 10.1 1.6 1 1 0 1 1 1 0 HBS1 N-terminus Glyco_hydro_59 PF02057.15 CDJ65803.1 - 0.093 11.9 0.9 0.11 11.7 0.9 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 DUF2057 PF09829.9 CDJ65803.1 - 0.38 10.9 8.6 0.41 10.8 8.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF3138 PF11336.8 CDJ65803.1 - 0.47 9.0 19.2 0.64 8.6 19.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Kinesin_assoc PF16183.5 CDJ65803.1 - 0.74 9.9 3.1 0.91 9.6 3.1 1.1 1 0 0 1 1 1 0 Kinesin-associated ISG65-75 PF11727.8 CDJ65803.1 - 0.91 8.7 12.8 1.1 8.4 12.8 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF1840 PF08895.11 CDJ65803.1 - 3.3 8.1 8.3 12 6.3 8.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) TFIIA PF03153.13 CDJ65803.1 - 4.8 7.1 10.8 5.2 6.9 10.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rcd1 PF04078.13 CDJ65804.1 - 1.8e-22 79.9 0.1 2.1e-22 79.7 0.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TetR_C_11 PF16859.5 CDJ65804.1 - 0.026 14.8 0.2 0.13 12.6 0.1 1.8 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3425 PF11905.8 CDJ65805.1 - 0.054 13.5 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) Retrotrans_gag PF03732.17 CDJ65805.1 - 0.061 13.6 0.0 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 Retrotransposon gag protein RVP_2 PF08284.11 CDJ65806.1 - 3.3e-06 26.9 0.0 5.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ65806.1 - 3.9e-05 24.2 0.0 6.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ65806.1 - 9.9e-05 22.8 0.0 0.0002 21.9 0.0 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ65806.1 - 0.0056 16.5 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ65806.1 - 0.052 13.9 0.0 0.14 12.5 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease D-ser_dehydrat PF14031.6 CDJ65806.1 - 0.1 13.3 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine dehydratase domain Activator_LAG-3 PF11498.8 CDJ65807.1 - 0.1 11.6 11.1 0.11 11.4 11.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FTCD_C PF04961.12 CDJ65807.1 - 2.5 7.8 4.3 0.92 9.2 1.7 1.6 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase TH1 PF04858.13 CDJ65808.1 - 0.0015 17.3 0.0 0.0041 15.8 0.0 1.6 2 0 0 2 2 2 1 TH1 protein Spt20 PF12090.8 CDJ65808.1 - 0.11 12.1 6.1 0.15 11.6 6.1 1.2 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ65809.1 - 5.2e-08 32.8 26.0 1.3e-05 25.0 10.5 2.7 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein AAA_6 PF12774.7 CDJ65809.1 - 0.7 8.8 4.2 1 8.3 2.9 1.8 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region CPSF100_C PF13299.6 CDJ65809.1 - 1.1 9.4 0.0 1.1 9.4 0.0 4.0 3 1 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DUF3446 PF11928.8 CDJ65809.1 - 6.3 7.2 34.7 4.6 7.6 4.9 4.5 4 0 0 4 4 4 0 Early growth response N-terminal domain DUF1645 PF07816.11 CDJ65811.1 - 0.0016 19.1 0.7 0.0029 18.2 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) PAP1 PF08601.10 CDJ65811.1 - 0.094 12.4 3.9 0.13 11.9 3.9 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 SR-25 PF10500.9 CDJ65811.1 - 0.27 10.8 17.4 0.48 10.0 17.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ65811.1 - 6.5 4.7 14.3 8.3 4.4 14.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.11 CDJ65811.1 - 8.9 4.4 10.4 11 4.1 10.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IMUP PF15761.5 CDJ65811.1 - 9.7 6.9 19.9 18 6.1 19.0 1.9 1 1 0 1 1 1 0 Immortalisation up-regulated protein ETRAMP PF09716.10 CDJ65812.1 - 0.13 12.4 0.7 0.16 12.1 0.7 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) BAF1_ABF1 PF04684.13 CDJ65812.1 - 1.7 7.6 16.7 1.7 7.6 16.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NAP PF00956.18 CDJ65814.1 - 3.1e-19 69.2 0.0 8.2e-19 67.8 0.0 1.5 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) PROCN PF08083.11 CDJ65815.1 - 2.9e-230 764.0 6.2 4.2e-230 763.5 6.2 1.2 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CDJ65815.1 - 5.8e-124 412.2 0.3 9.9e-124 411.4 0.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CDJ65815.1 - 1e-87 292.1 2.3 2.1e-87 291.0 2.3 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CDJ65815.1 - 4.4e-82 273.5 0.2 9.4e-82 272.4 0.2 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CDJ65815.1 - 1.2e-71 239.1 0.0 2.1e-71 238.2 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 CDJ65815.1 - 6.1e-46 154.7 0.1 1.3e-45 153.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 TFIIA PF03153.13 CDJ65815.1 - 2.1 8.3 21.7 0.19 11.7 15.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Leu_zip PF15294.6 CDJ65817.1 - 0.017 14.6 1.7 0.017 14.6 1.7 2.2 1 1 2 3 3 3 0 Leucine zipper SPX PF03105.19 CDJ65818.1 - 0.21 11.4 6.3 0.31 10.9 6.3 1.2 1 0 0 1 1 1 0 SPX domain Rpp20 PF12328.8 CDJ65818.1 - 0.68 9.9 3.4 4.9 7.1 1.5 2.2 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P BASP1 PF05466.12 CDJ65818.1 - 7.5 6.5 55.5 0.27 11.2 49.0 1.7 2 0 0 2 2 2 0 Brain acid soluble protein 1 (BASP1 protein) MPC PF03650.13 CDJ65819.1 - 1e-12 48.2 0.4 1.4e-11 44.5 0.1 2.0 1 1 1 2 2 2 2 Mitochondrial pyruvate carriers Herpes_pp85 PF04637.12 CDJ65819.1 - 0.081 11.3 3.0 0.09 11.2 3.0 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SR-25 PF10500.9 CDJ65819.1 - 0.37 10.4 13.9 0.44 10.1 13.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF515 PF04415.12 CDJ65819.1 - 2.9 6.2 9.8 3.1 6.1 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) LSM PF01423.22 CDJ65820.1 - 8.9e-19 67.0 0.0 1.1e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.25 CDJ65821.1 - 3.1e-47 161.2 6.3 5.2e-33 114.5 0.0 3.4 4 0 0 4 4 4 2 Protein kinase domain YueH PF14166.6 CDJ65821.1 - 3.1 7.7 6.8 4.9 7.1 0.0 3.9 3 0 0 3 3 3 0 YueH-like protein Glycolytic PF00274.19 CDJ65822.1 - 2.6e-168 559.2 0.0 2.9e-168 559.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Rad10 PF03834.14 CDJ65823.1 - 3.1e-24 85.2 0.0 3.1e-24 85.2 0.0 1.7 2 0 0 2 2 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Dapper PF15268.6 CDJ65823.1 - 6.5e-05 22.0 20.9 7.1e-05 21.9 20.9 1.2 1 0 0 1 1 1 1 Dapper HHH_5 PF14520.6 CDJ65823.1 - 0.0068 17.0 0.0 0.024 15.3 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 CDJ65823.1 - 0.012 15.4 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ndc1_Nup PF09531.10 CDJ65823.1 - 0.027 13.2 23.2 0.036 12.8 23.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase_fungal PF17667.1 CDJ65823.1 - 0.054 12.3 13.8 0.075 11.8 13.8 1.2 1 0 0 1 1 1 0 Fungal protein kinase VIT1 PF01988.19 CDJ65823.1 - 0.061 13.2 8.7 0.16 11.9 8.7 1.7 1 0 0 1 1 1 0 VIT family Mem_trans PF03547.18 CDJ65823.1 - 0.062 11.7 1.6 0.077 11.4 1.6 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF4638 PF15472.6 CDJ65823.1 - 0.093 12.5 29.8 0.17 11.6 29.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) HHH_2 PF12826.7 CDJ65823.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif V_ATPase_I PF01496.19 CDJ65823.1 - 0.23 9.3 27.1 0.35 8.7 27.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ65823.1 - 1.4 7.6 41.2 2.1 7.0 41.2 1.2 1 0 0 1 1 1 0 Presenilin DUF763 PF05559.11 CDJ65823.1 - 2.4 7.3 18.6 3.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF763) DUF2877 PF11392.8 CDJ65823.1 - 6.5 7.5 0.0 6.5 7.5 0.0 3.7 2 2 1 3 3 2 0 Protein of unknown function (DUF2877) Otopetrin PF03189.13 CDJ65823.1 - 9 5.0 22.0 28 3.4 22.0 1.8 1 1 0 1 1 1 0 Otopetrin Thioredoxin PF00085.20 CDJ65824.1 - 0.0012 18.8 0.4 0.007 16.3 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 CDJ65824.1 - 0.0015 18.5 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain MDMPI_N PF11716.8 CDJ65824.1 - 0.25 12.0 3.8 0.87 10.3 0.0 2.3 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain AMP-binding PF00501.28 CDJ65826.1 - 1.1e-33 116.5 0.0 2.7e-33 115.2 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 CDJ65827.1 - 1.9e-80 270.1 0.5 4.2e-80 269.0 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CDJ65827.1 - 6.2e-40 135.9 0.0 1.9e-39 134.3 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 CDJ65827.1 - 4.8e-34 117.9 0.5 3.1e-21 75.9 0.0 2.7 3 0 0 3 3 3 2 Polyketide synthase dehydratase AMP-binding PF00501.28 CDJ65827.1 - 6.1e-28 97.6 0.0 1e-26 93.5 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.21 CDJ65827.1 - 9.5e-24 84.5 0.1 1.6e-23 83.8 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.25 CDJ65827.1 - 3.1e-11 43.5 0.2 8.3e-11 42.1 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 CDJ65827.1 - 4.3e-09 36.8 0.0 1.2e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 CDJ65827.1 - 8.2e-05 22.1 0.4 8.2e-05 22.1 0.4 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain AMP-binding_C_2 PF14535.6 CDJ65827.1 - 0.0017 18.6 0.0 0.0082 16.4 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACP_syn_III PF08545.10 CDJ65827.1 - 0.028 14.3 0.5 0.11 12.4 0.5 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ribosomal_L22 PF00237.19 CDJ65828.1 - 3.4e-18 65.8 0.3 4.9e-18 65.2 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Longin PF13774.6 CDJ65829.1 - 9.3e-08 32.0 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CDJ65829.1 - 0.0098 15.7 0.8 0.016 15.0 0.8 1.3 1 0 0 1 1 1 1 Synaptobrevin Ccdc124 PF06244.12 CDJ65832.1 - 3.8e-33 114.8 27.2 1.9e-30 106.1 27.2 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 CDJ65832.1 - 0.00011 22.6 0.3 0.00011 22.6 0.3 2.6 2 1 0 2 2 2 1 HMG (high mobility group) box CHDNT PF08073.12 CDJ65832.1 - 0.016 15.2 0.3 0.027 14.4 0.3 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 CDJ65832.1 - 2.8 8.5 12.2 2.1e+02 2.4 12.2 2.3 1 1 0 1 1 1 0 YABBY protein TMPIT PF07851.13 CDJ65832.1 - 6.5 5.9 7.8 8.3 5.5 7.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.11 CDJ65833.1 - 0.011 14.6 22.2 0.013 14.4 14.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein PRO8NT PF08082.11 CDJ65833.1 - 0.029 14.3 0.2 0.062 13.2 0.2 1.5 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain MIP-T3_C PF17749.1 CDJ65833.1 - 0.049 13.6 10.1 0.073 13.0 4.7 2.9 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region CENP-F_leu_zip PF10473.9 CDJ65833.1 - 0.32 11.0 31.3 0.14 12.2 5.7 3.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fzo_mitofusin PF04799.13 CDJ65833.1 - 0.41 10.2 5.5 1 8.9 5.5 1.7 1 0 0 1 1 1 0 fzo-like conserved region DUF641 PF04859.12 CDJ65833.1 - 0.66 10.3 11.3 0.88 9.9 6.7 2.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF1216 PF06746.11 CDJ65833.1 - 1.8 8.6 6.1 4.2 7.4 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) FlaC_arch PF05377.11 CDJ65833.1 - 3.1 8.3 5.5 8 6.9 2.3 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 CDJ65833.1 - 3.7 7.6 8.0 0.21 11.6 0.8 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 CDJ65833.1 - 4.4 5.1 8.8 7.3 4.4 8.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 CDJ65833.1 - 7.9 7.2 19.8 0.1 13.3 3.3 3.6 1 1 2 3 3 3 0 Initiation control protein YabA WD40 PF00400.32 CDJ65834.1 - 1e-13 51.5 0.5 6.9e-06 26.7 0.0 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat tRNA-synt_1c PF00749.21 CDJ65835.1 - 9.7e-64 215.2 0.0 2.3e-52 177.8 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain WD40 PF00400.32 CDJ65835.1 - 2.6e-32 110.3 24.2 3.1e-07 31.0 0.6 11.0 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ65835.1 - 1.8e-12 47.3 0.1 0.096 13.0 0.0 7.1 5 3 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ65835.1 - 0.081 11.9 0.3 27 3.6 0.0 3.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Hydrolase_4 PF12146.8 CDJ65836.1 - 2.5e-12 46.6 0.3 2.5e-08 33.5 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CDJ65836.1 - 2.9e-09 36.7 0.2 2.4e-06 27.2 0.0 3.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CDJ65836.1 - 1.4e-07 32.4 0.0 3.7e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ65836.1 - 0.00072 19.3 0.1 0.014 15.0 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 CDJ65836.1 - 0.0022 17.7 0.1 0.054 13.1 0.0 2.2 1 1 1 2 2 2 1 Serine hydrolase (FSH1) DUF818 PF05677.12 CDJ65836.1 - 0.014 14.4 0.1 0.021 13.8 0.1 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Fe_dep_repr_C PF02742.15 CDJ65836.1 - 0.017 15.2 0.0 12 6.1 0.0 3.3 4 0 0 4 4 4 0 Iron dependent repressor, metal binding and dimerisation domain Abhydrolase_2 PF02230.16 CDJ65836.1 - 0.033 14.0 0.1 0.32 10.7 0.0 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Pkinase PF00069.25 CDJ65837.1 - 1.1e-23 84.0 3.9 2.2e-11 43.7 0.0 4.0 5 0 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65837.1 - 6e-09 35.6 2.4 0.00028 20.3 0.0 4.8 5 0 0 5 5 5 3 Protein tyrosine kinase Ribonuc_P_40 PF08584.11 CDJ65837.1 - 0.35 10.1 5.2 0.78 9.0 5.2 1.6 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit DHHC PF01529.20 CDJ65838.1 - 4.2e-38 130.5 12.2 7.5e-37 126.4 6.5 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase TMEM213 PF15192.6 CDJ65838.1 - 0.059 13.3 4.3 0.12 12.4 3.7 1.8 2 0 0 2 2 2 0 TMEM213 family Yip1 PF04893.17 CDJ65838.1 - 0.071 12.8 9.2 0.25 11.0 0.2 2.2 2 0 0 2 2 2 0 Yip1 domain RDD PF06271.12 CDJ65838.1 - 1.6 8.9 9.2 5.5 7.2 1.0 2.2 2 0 0 2 2 2 0 RDD family Colicin_V PF02674.16 CDJ65838.1 - 2.2 8.2 18.6 0.11 12.5 6.2 2.5 2 1 0 2 2 2 0 Colicin V production protein DUF2207 PF09972.9 CDJ65838.1 - 3 6.5 4.1 3 6.5 0.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Bac_export_2 PF01312.19 CDJ65838.1 - 6.8 5.8 6.4 14 4.8 0.7 2.0 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family START PF01852.19 CDJ65839.1 - 1.2e-11 44.4 0.0 9.7e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 START domain TP_methylase PF00590.20 CDJ65841.1 - 3.1e-21 76.3 0.0 7.3e-21 75.1 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases UQ_con PF00179.26 CDJ65842.1 - 1.7e-47 160.6 0.0 2e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ65842.1 - 0.00028 20.6 0.0 0.00032 20.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ65842.1 - 0.013 15.7 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain Rhomboid PF01694.22 CDJ65844.1 - 8.6e-18 64.8 14.7 4.6e-14 52.7 4.1 2.6 2 1 1 3 3 3 2 Rhomboid family DUF2705 PF10920.8 CDJ65844.1 - 0.0077 15.6 1.3 0.011 15.0 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2705) MFS_1 PF07690.16 CDJ65844.1 - 0.062 12.2 5.0 0.086 11.7 4.9 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily FKBP26_C PF18046.1 CDJ65844.1 - 0.081 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 FKBP26_C-terminal CoaE PF01121.20 CDJ65845.1 - 4.9e-48 163.2 0.0 6.1e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_28 PF13521.6 CDJ65845.1 - 9.9e-06 25.9 0.0 2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDJ65845.1 - 0.00051 20.6 0.0 0.0011 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ65845.1 - 0.068 13.3 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF3488 PF11992.8 CDJ65845.1 - 1.7 7.5 7.1 0.17 10.8 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) APG5 PF04106.12 CDJ65846.1 - 8.3e-43 146.6 0.0 1.2e-42 146.0 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg5 Ribosomal_60s PF00428.19 CDJ65846.1 - 0.0035 17.9 5.2 0.0035 17.9 5.2 3.4 4 0 0 4 4 4 1 60s Acidic ribosomal protein YqfQ PF14181.6 CDJ65846.1 - 1.1 9.4 5.9 9.4 6.4 0.2 2.3 2 0 0 2 2 2 0 YqfQ-like protein SUIM_assoc PF16619.5 CDJ65847.1 - 0.034 14.2 12.9 0.63 10.1 6.8 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MMgT PF10270.9 CDJ65848.1 - 0.061 13.7 1.3 0.1 12.9 0.2 2.0 2 0 0 2 2 2 0 Membrane magnesium transporter NPH3 PF03000.14 CDJ65848.1 - 2.6 7.6 7.6 0.14 11.8 1.3 1.9 1 1 1 2 2 2 0 NPH3 family SUIM_assoc PF16619.5 CDJ65848.1 - 3.8 7.7 20.8 0.55 10.3 9.0 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ65848.1 - 4.2 7.3 23.1 0.53 10.2 16.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ65848.1 - 7.3 6.1 19.0 0.66 9.5 9.8 2.1 2 0 0 2 2 2 0 Spt20 family Med3 PF11593.8 CDJ65849.1 - 4.6 6.3 8.0 4.9 6.2 8.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4614 PF15391.6 CDJ65849.1 - 6.1 6.8 7.7 10 6.1 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SUIM_assoc PF16619.5 CDJ65850.1 - 0.0011 19.0 0.0 0.0011 19.0 0.0 6.3 4 2 1 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ65850.1 - 1.6 8.3 48.9 1.9 8.0 0.8 3.4 3 0 0 3 3 3 0 Spt20 family DUF389 PF04087.14 CDJ65850.1 - 2 8.4 12.1 0.2 11.7 0.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF389) CSN8_PSD8_EIF3K PF10075.9 CDJ65851.1 - 7.9e-07 29.1 0.4 1.5e-06 28.3 0.4 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 CDJ65851.1 - 0.07 13.6 0.1 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 PCI domain Spt20 PF12090.8 CDJ65851.1 - 0.18 11.4 6.8 2 7.9 2.2 2.2 2 0 0 2 2 2 0 Spt20 family QueH PF02677.14 CDJ65851.1 - 6.1 6.9 5.9 2.7 8.1 0.3 2.3 2 0 0 2 2 2 0 Epoxyqueuosine reductase QueH Utp14 PF04615.13 CDJ65851.1 - 8.3 4.8 10.0 10 4.5 10.0 1.3 1 0 0 1 1 1 0 Utp14 protein SUIM_assoc PF16619.5 CDJ65851.1 - 9 6.5 25.9 8 6.6 8.8 2.7 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 CDJ65852.1 - 0.018 15.1 0.6 0.018 15.1 0.6 11.8 9 3 1 10 10 10 0 Unstructured region C-term to UIM in Ataxin3 EF-hand_6 PF13405.6 CDJ65852.1 - 0.086 12.8 0.0 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain AF-4 PF05110.13 CDJ65854.1 - 0.00086 17.6 28.7 0.00086 17.6 28.7 2.2 2 0 0 2 2 2 2 AF-4 proto-oncoprotein CIAPIN1 PF05093.13 CDJ65854.1 - 0.55 10.8 11.1 2.3 8.8 2.6 2.9 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Spt20 PF12090.8 CDJ65854.1 - 1.7 8.2 53.0 0.23 11.0 21.1 2.5 3 0 0 3 3 3 0 Spt20 family eIF-3_zeta PF05091.12 CDJ65854.1 - 2.2 7.2 21.1 2.6 6.9 4.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CCSAP PF15748.5 CDJ65854.1 - 4.2 7.5 39.6 4.1 7.5 19.9 2.5 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Roughex PF06020.11 CDJ65854.1 - 5.3 6.0 24.8 2 7.4 7.6 2.3 2 0 0 2 2 2 0 Drosophila roughex protein Suf PF05843.14 CDJ65854.1 - 7.8 6.4 22.0 2.1 8.3 3.9 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RVP_2 PF08284.11 CDJ65856.1 - 1.4e-09 37.8 0.0 2.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ65856.1 - 8.9e-07 29.4 0.0 2.2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ65856.1 - 1.4e-06 28.9 0.0 2.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF3552 PF12072.8 CDJ65856.1 - 0.011 15.2 1.8 0.017 14.5 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Asp_protease PF09668.10 CDJ65856.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 CDJ65857.1 - 3.2e-27 94.8 0.1 6.7e-27 93.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ65857.1 - 9.3e-21 73.7 0.0 2.1e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ65857.1 - 6.3e-15 55.4 0.2 7.6e-13 48.7 0.0 2.4 2 1 0 2 2 2 2 Integrase core domain Linker_histone PF00538.19 CDJ65857.1 - 0.043 14.2 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 linker histone H1 and H5 family LRR_4 PF12799.7 CDJ65858.1 - 4.1e-35 119.2 34.7 7.3e-08 32.6 2.5 7.4 2 1 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ65858.1 - 2.3e-30 104.1 28.1 1.7e-08 34.1 1.1 5.6 4 1 2 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 CDJ65858.1 - 1.3e-20 73.6 17.0 8.8e-06 25.3 0.6 4.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 CDJ65858.1 - 0.027 15.0 38.1 1 10.2 0.4 9.2 8 2 1 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 CDJ65858.1 - 0.5 10.5 29.9 0.26 11.4 0.3 8.0 8 1 0 8 8 8 0 Leucine Rich repeat DUF2322 PF10084.9 CDJ65858.1 - 1.3 9.1 3.0 11 6.1 0.1 3.6 4 1 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2322) RCC1 PF00415.18 CDJ65859.1 - 1.8e-22 79.7 19.3 4.1e-08 33.7 0.2 7.8 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ65859.1 - 1.1e-16 60.1 29.8 5.1e-06 26.1 3.6 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat zf-LITAF-like PF10601.9 CDJ65860.1 - 1.3e-13 51.0 6.4 1.3e-13 51.0 6.4 2.3 1 1 1 2 2 2 1 LITAF-like zinc ribbon domain zinc_ribbon_15 PF17032.5 CDJ65860.1 - 0.00067 20.4 2.7 0.094 13.5 0.4 2.7 2 0 0 2 2 2 2 zinc-ribbon family RecR PF02132.15 CDJ65860.1 - 3.2 7.4 6.0 0.67 9.6 1.8 1.9 2 0 0 2 2 2 0 RecR protein Elf1 PF05129.13 CDJ65860.1 - 5 7.2 6.2 10 6.2 1.7 2.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Lung_7-TM_R PF06814.13 CDJ65861.1 - 0.0036 16.6 2.0 0.0058 15.9 1.8 1.4 1 1 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 CDJ65861.1 - 0.0039 16.6 0.4 0.0077 15.7 0.4 1.4 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain SHNi-TPR PF10516.9 CDJ65861.1 - 0.13 11.8 0.4 0.48 9.9 0.0 2.1 2 0 0 2 2 2 0 SHNi-TPR MIF4G PF02854.19 CDJ65862.1 - 2.4e-31 109.0 1.9 3.7e-31 108.4 1.9 1.3 1 0 0 1 1 1 1 MIF4G domain P_C PF06640.11 CDJ65863.1 - 9.8 6.3 11.7 14 5.8 11.7 1.2 1 0 0 1 1 1 0 P protein C-terminus CLP1_N PF16573.5 CDJ65865.1 - 9.7e-11 41.7 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor FA_desaturase PF00487.24 CDJ65865.1 - 0.086 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Fatty acid desaturase RSRP PF17069.5 CDJ65866.1 - 0.014 15.0 14.5 0.036 13.6 14.5 1.7 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 SUIM_assoc PF16619.5 CDJ65867.1 - 0.3 11.2 0.0 0.14 12.2 10.4 12.9 8 3 3 11 11 11 0 Unstructured region C-term to UIM in Ataxin3 Kinase-like PF14531.6 CDJ65869.1 - 3.8e-05 23.1 0.0 8e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 CDJ65869.1 - 0.035 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain CCDC53 PF10152.9 CDJ65869.1 - 0.45 10.9 5.4 0.13 12.7 0.6 2.2 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 CDJ65869.1 - 3.8 7.1 11.5 7.1 6.2 11.5 1.3 1 0 0 1 1 1 0 Spt20 family WD40 PF00400.32 CDJ65870.1 - 6e-10 39.6 1.8 2.4e-05 25.0 0.0 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.8 CDJ65870.1 - 0.0018 17.0 0.8 0.058 12.0 0.8 2.1 1 1 0 1 1 1 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CDJ65870.1 - 0.046 14.0 0.0 0.51 10.7 0.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Utp8 PF10395.9 CDJ65870.1 - 0.058 11.9 0.0 0.059 11.9 0.0 1.0 1 0 0 1 1 1 0 Utp8 family MMS1_N PF10433.9 CDJ65870.1 - 0.099 11.3 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term SPX PF03105.19 CDJ65871.1 - 0.01 15.8 9.2 0.0098 15.8 9.2 1.0 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 CDJ65871.1 - 0.013 15.2 21.1 0.018 14.7 21.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 CDJ65871.1 - 0.25 11.3 14.3 0.16 12.0 12.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 CDJ65871.1 - 0.27 10.0 8.5 0.29 9.9 8.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.15 CDJ65871.1 - 0.54 9.8 3.0 0.56 9.7 3.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist S100PBPR PF15427.6 CDJ65871.1 - 1.1 8.4 9.4 1.2 8.3 9.4 1.1 1 0 0 1 1 1 0 S100P-binding protein CCDC106 PF15794.5 CDJ65871.1 - 2.5 7.8 8.2 2.8 7.6 8.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SOG2 PF10428.9 CDJ65871.1 - 2.8 7.0 17.7 2.8 7.0 17.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 CDJ65871.1 - 3.5 6.1 11.1 3.8 6.0 11.1 1.1 1 0 0 1 1 1 0 Macoilin family CDC27 PF09507.10 CDJ65871.1 - 6.3 6.1 13.1 6.5 6.0 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Presenilin PF01080.17 CDJ65871.1 - 6.7 5.4 6.4 7.8 5.1 6.4 1.0 1 0 0 1 1 1 0 Presenilin Peroxin-3 PF04882.12 CDJ65871.1 - 8.6 5.2 10.4 9.3 5.1 10.4 1.0 1 0 0 1 1 1 0 Peroxin-3 Calpain_u2 PF16648.5 CDJ65873.1 - 0.0045 17.4 0.3 0.023 15.1 0.1 2.3 2 0 0 2 2 2 1 Unstructured region on Calpain-3 DDRGK PF09756.9 CDJ65874.1 - 0.013 15.1 13.7 0.015 14.9 13.7 1.1 1 0 0 1 1 1 0 DDRGK domain Spt20 PF12090.8 CDJ65874.1 - 0.041 13.5 11.2 0.047 13.3 11.2 1.1 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ65874.1 - 0.28 9.9 6.4 0.32 9.7 6.4 1.2 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 CDJ65874.1 - 0.55 10.0 3.2 0.61 9.8 3.2 1.2 1 0 0 1 1 1 0 Connexin ALMT PF11744.8 CDJ65874.1 - 0.85 8.4 3.5 0.98 8.2 3.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter eIF-3_zeta PF05091.12 CDJ65874.1 - 1 8.3 10.4 1 8.2 10.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Vfa1 PF08432.10 CDJ65874.1 - 1.1 9.5 11.7 1.4 9.2 11.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ctr PF04145.15 CDJ65874.1 - 1.6 9.3 4.0 2 9.0 4.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF2722 PF10846.8 CDJ65874.1 - 2.2 7.1 14.4 2.8 6.8 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF5427 PF10310.9 CDJ65874.1 - 2.4 7.0 20.8 2.9 6.8 20.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CDC45 PF02724.14 CDJ65874.1 - 4 5.6 11.8 5 5.3 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L7Ae PF01248.26 CDJ65876.1 - 5.5e-28 96.6 0.5 7e-28 96.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 CDJ65876.1 - 0.0024 18.1 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Amastin PF07344.11 CDJ65877.1 - 0.0041 17.0 23.9 0.096 12.5 11.6 2.8 2 1 1 3 3 3 2 Amastin surface glycoprotein Endomucin PF07010.12 CDJ65878.1 - 0.048 13.6 2.0 0.053 13.5 0.2 1.8 1 1 1 2 2 2 0 Endomucin zf-RING_2 PF13639.6 CDJ65879.1 - 1.2e-10 41.5 3.0 2.3e-10 40.6 3.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CDJ65879.1 - 3.6e-08 33.6 2.5 1.1e-07 32.0 2.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ65879.1 - 4.2e-08 32.9 1.9 8.2e-08 32.0 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ65879.1 - 1.7e-06 27.8 2.6 3.4e-06 26.8 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ65879.1 - 1.2e-05 25.1 2.2 2.5e-05 24.2 2.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ65879.1 - 1.7e-05 24.7 2.4 2.3e-05 24.3 0.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ65879.1 - 2.1e-05 24.3 4.3 3.8e-05 23.4 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ65879.1 - 8.7e-05 22.2 3.1 8.7e-05 22.2 3.1 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CDJ65879.1 - 0.00019 21.4 2.2 0.00019 21.4 2.2 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CDJ65879.1 - 0.0012 18.4 3.7 0.0025 17.4 3.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CDJ65879.1 - 0.0018 18.1 6.4 0.0036 17.1 6.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rtf2 PF04641.12 CDJ65879.1 - 0.0018 17.7 5.0 0.0018 17.7 5.0 4.0 4 1 0 4 4 3 1 Rtf2 RING-finger SprA-related PF12118.8 CDJ65879.1 - 0.0056 15.9 25.5 0.0056 15.9 25.5 4.7 4 1 0 5 5 2 1 SprA-related family zf-C3HC4_4 PF15227.6 CDJ65879.1 - 0.029 14.5 3.6 0.11 12.7 3.6 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CDJ65879.1 - 0.032 14.4 2.8 0.087 13.0 2.8 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 CDJ65879.1 - 0.11 12.7 3.6 0.31 11.2 3.6 1.9 1 0 0 1 1 1 0 RING-variant domain DUF2408 PF10303.9 CDJ65879.1 - 1.6 9.3 8.8 0.51 10.9 2.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) RNA_Me_trans PF04252.13 CDJ65879.1 - 1.9 8.0 6.7 0.12 11.9 0.3 2.1 2 0 0 2 2 2 0 Predicted SAM-dependent RNA methyltransferase zf-CCCH PF00642.24 CDJ65880.1 - 4.7e-08 32.7 16.2 8.8e-05 22.3 1.5 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CDJ65880.1 - 6.3e-05 23.2 9.2 0.014 15.6 2.6 3.9 2 2 1 3 3 3 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 CDJ65880.1 - 0.003 17.3 2.9 0.003 17.3 2.9 4.1 4 1 0 4 4 4 1 CCCH-type zinc finger Torus PF16131.5 CDJ65880.1 - 0.037 14.7 0.1 0.037 14.7 0.1 5.3 4 2 1 5 5 5 0 Torus domain zf_CCCH_4 PF18345.1 CDJ65880.1 - 0.87 9.7 15.9 2.2 8.4 3.9 4.6 3 2 0 3 3 3 0 Zinc finger domain Chromo PF00385.24 CDJ65881.1 - 1.4e-07 31.3 0.1 2.6e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Macoilin PF09726.9 CDJ65881.1 - 0.13 10.8 0.7 0.2 10.1 0.7 1.3 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ65881.1 - 7.5 5.3 7.1 13 4.5 7.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pox_A_type_inc PF04508.12 CDJ65882.1 - 0.0032 17.2 0.3 0.0032 17.2 0.3 2.8 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 CDJ65882.1 - 0.0045 17.0 6.3 0.0045 17.0 6.3 1.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 CDJ65882.1 - 0.005 16.7 0.7 0.035 14.0 0.1 2.1 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4201 PF13870.6 CDJ65882.1 - 0.049 13.4 8.1 0.057 13.2 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) SlyX PF04102.12 CDJ65882.1 - 3.1 8.5 8.2 0.51 11.0 1.3 2.2 1 1 1 2 2 2 0 SlyX DUF1822 PF08852.11 CDJ65883.1 - 0.24 10.4 2.5 0.39 9.7 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Fzo_mitofusin PF04799.13 CDJ65883.1 - 0.43 10.1 2.4 0.7 9.4 2.4 1.3 1 0 0 1 1 1 0 fzo-like conserved region KxDL PF10241.9 CDJ65883.1 - 0.76 10.1 4.9 2.8 8.3 4.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF2561 PF10812.8 CDJ65883.1 - 1.1 9.3 4.0 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) LCAT PF02450.15 CDJ65885.1 - 1.2e-26 93.8 0.0 7.2e-23 81.4 0.0 2.5 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Chromo PF00385.24 CDJ65886.1 - 3.2e-06 27.0 0.0 6.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.25 CDJ65887.1 - 5.2e-17 62.1 0.1 7.4e-14 51.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65887.1 - 1.6e-09 37.4 0.0 2.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ65887.1 - 0.012 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 CDJ65887.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_methylase PF00145.17 CDJ65888.1 - 8e-36 124.0 0.0 2.8e-34 119.0 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Roughex PF06020.11 CDJ65888.1 - 0.61 9.1 6.3 0.078 12.1 1.3 1.8 2 0 0 2 2 2 0 Drosophila roughex protein GAS PF13851.6 CDJ65889.1 - 9e-30 103.5 21.2 9e-30 103.5 21.2 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 CDJ65889.1 - 8.3e-06 25.8 21.7 8.3e-06 25.8 21.7 2.7 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH XhlA PF10779.9 CDJ65889.1 - 0.058 13.6 0.5 0.058 13.6 0.5 4.2 4 0 0 4 4 4 0 Haemolysin XhlA GRIM-19 PF06212.12 CDJ65889.1 - 0.59 10.1 3.5 1.8 8.6 3.5 1.8 1 0 0 1 1 1 0 GRIM-19 protein DUF812 PF05667.11 CDJ65889.1 - 7.3 5.3 49.8 4.6 6.0 35.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) GCP_C_terminal PF04130.13 CDJ65891.1 - 3.6e-25 89.1 1.7 3.6e-25 89.1 1.7 3.4 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CDJ65891.1 - 1.3e-22 80.9 0.0 6.9e-22 78.5 0.0 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal TFIIA PF03153.13 CDJ65893.1 - 0.00032 20.8 34.1 0.00048 20.3 34.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit LAP1C PF05609.12 CDJ65893.1 - 0.0027 16.9 10.9 0.0033 16.6 10.9 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 CDJ65893.1 - 4.6 4.2 20.1 5.5 4.0 20.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SR-25 PF10500.9 CDJ65894.1 - 0.0045 16.6 19.0 0.0045 16.6 19.0 5.9 7 0 0 7 7 7 1 Nuclear RNA-splicing-associated protein TPR_2 PF07719.17 CDJ65894.1 - 0.013 15.6 0.5 0.013 15.6 0.5 9.5 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ65894.1 - 0.095 12.6 0.1 0.095 12.6 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ65894.1 - 1.8 9.0 9.8 2.7 8.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SID-1_RNA_chan PF13965.6 CDJ65894.1 - 8.7 4.6 5.0 4.6 5.5 0.4 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF4179 PF13786.6 CDJ65895.1 - 5 7.7 0.0 5 7.7 0.0 5.9 7 2 0 7 7 7 0 Domain of unknown function (DUF4179) DUF2894 PF11445.8 CDJ65896.1 - 0.0012 19.4 2.6 0.0012 19.4 2.6 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2894) SUIM_assoc PF16619.5 CDJ65896.1 - 0.081 13.0 1.9 0.15 12.1 1.9 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ65897.1 - 0.0001 22.5 34.6 0.00011 22.4 34.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ65897.1 - 0.0048 17.6 26.6 0.0091 16.7 26.6 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ65897.1 - 0.0048 16.9 19.4 0.0057 16.7 19.4 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DDHD PF02862.17 CDJ65897.1 - 0.0053 16.9 9.8 0.0059 16.8 9.8 1.1 1 0 0 1 1 1 1 DDHD domain MMR1 PF08505.10 CDJ65897.1 - 0.0082 16.5 18.5 0.0098 16.2 18.5 1.1 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein Serinc PF03348.15 CDJ65897.1 - 0.0096 14.9 2.6 0.0086 15.1 2.6 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Vfa1 PF08432.10 CDJ65897.1 - 0.011 16.1 17.9 0.013 15.9 17.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SID-1_RNA_chan PF13965.6 CDJ65897.1 - 0.011 14.2 0.9 0.011 14.2 0.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3408 PF11888.8 CDJ65897.1 - 0.014 15.6 18.3 0.02 15.1 18.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Velvet PF11754.8 CDJ65897.1 - 0.018 15.0 12.4 0.019 14.9 12.4 1.2 1 0 0 1 1 1 0 Velvet factor SAPS PF04499.15 CDJ65897.1 - 0.023 13.5 8.3 0.024 13.4 8.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AIF_C PF14721.6 CDJ65897.1 - 0.033 14.5 10.2 0.045 14.1 10.2 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SpoIIP PF07454.11 CDJ65897.1 - 0.036 13.5 17.3 0.042 13.3 17.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Neur_chan_memb PF02932.16 CDJ65897.1 - 0.067 13.2 9.7 0.074 13.1 9.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 CDJ65897.1 - 0.094 9.8 14.6 0.093 9.8 14.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 CDJ65897.1 - 0.097 10.8 14.6 0.11 10.7 14.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 CDJ65897.1 - 0.11 11.5 9.3 0.13 11.2 9.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4820 PF16091.5 CDJ65897.1 - 0.12 11.7 11.8 0.18 11.2 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) eIF-3_zeta PF05091.12 CDJ65897.1 - 0.13 11.2 22.9 0.15 11.0 22.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Endostatin PF06482.11 CDJ65897.1 - 0.14 11.6 13.8 0.15 11.5 13.8 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CobT PF06213.12 CDJ65897.1 - 0.18 11.2 26.5 0.24 10.7 26.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Borrelia_P83 PF05262.11 CDJ65897.1 - 0.19 10.1 15.8 0.2 10.1 15.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 CDJ65897.1 - 0.21 10.3 21.0 0.26 10.0 21.0 1.1 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CDJ65897.1 - 0.24 11.6 13.9 0.31 11.2 13.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S64 PF08192.11 CDJ65897.1 - 0.28 9.6 16.8 0.34 9.4 16.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.9 CDJ65897.1 - 0.34 9.1 30.7 0.41 8.9 30.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Plasmodium_Vir PF05795.11 CDJ65897.1 - 0.37 10.2 7.8 0.37 10.2 7.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TERB2 PF15101.6 CDJ65897.1 - 0.38 10.8 21.8 0.48 10.4 21.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pal1 PF08316.11 CDJ65897.1 - 0.38 11.5 8.0 0.61 10.8 8.0 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein RR_TM4-6 PF06459.12 CDJ65897.1 - 0.42 10.4 21.5 0.55 10.0 21.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.6 CDJ65897.1 - 0.43 10.5 24.6 0.53 10.2 24.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO MCM_bind PF09739.9 CDJ65897.1 - 0.48 8.8 15.9 0.58 8.5 15.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor EOS1 PF12326.8 CDJ65897.1 - 0.53 10.2 8.1 0.72 9.8 8.1 1.3 1 0 0 1 1 1 0 N-glycosylation protein Ndc1_Nup PF09531.10 CDJ65897.1 - 0.54 8.9 14.1 0.59 8.8 14.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AAA_23 PF13476.6 CDJ65897.1 - 0.56 10.7 19.7 0.62 10.5 19.7 1.1 1 0 0 1 1 1 0 AAA domain AFT PF08731.11 CDJ65897.1 - 0.58 10.6 9.8 0.86 10.0 9.8 1.3 1 0 0 1 1 1 0 Transcription factor AFT Transketolase_N PF00456.21 CDJ65897.1 - 0.63 8.9 6.3 0.81 8.6 6.3 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Rtf2 PF04641.12 CDJ65897.1 - 0.67 9.3 20.0 0.86 8.9 20.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1764 PF08576.10 CDJ65897.1 - 0.67 10.9 14.9 1.1 10.2 14.9 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) NPR3 PF03666.13 CDJ65897.1 - 0.72 8.6 16.3 0.85 8.3 16.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF853 PF05872.12 CDJ65897.1 - 0.78 8.2 14.4 1.1 7.8 14.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FAM60A PF15396.6 CDJ65897.1 - 0.88 9.5 15.1 1.1 9.2 15.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF3292 PF11696.8 CDJ65897.1 - 0.9 7.8 11.8 1.1 7.6 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) EIIBC-GUT_N PF03612.14 CDJ65897.1 - 0.99 9.1 14.0 1.6 8.4 14.0 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SPT16 PF08644.11 CDJ65897.1 - 1 9.6 13.3 1.3 9.1 13.3 1.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Gti1_Pac2 PF09729.9 CDJ65897.1 - 1 9.4 15.3 1.3 9.0 15.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family ATAD4 PF15321.6 CDJ65897.1 - 1.1 10.6 15.2 2 9.8 15.2 1.4 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Peroxin-13_N PF04088.13 CDJ65897.1 - 1.2 9.4 8.4 2.2 8.5 8.4 1.5 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Band_3_cyto PF07565.13 CDJ65897.1 - 1.3 8.8 17.1 1.6 8.5 17.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SLC12 PF03522.15 CDJ65897.1 - 1.3 8.0 17.6 1.5 7.7 17.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4228 PF14009.6 CDJ65897.1 - 1.4 9.3 10.9 1.9 8.8 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) EPL1 PF10513.9 CDJ65897.1 - 2.1 8.7 19.6 2.8 8.3 19.6 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like FAM176 PF14851.6 CDJ65897.1 - 2.6 7.7 11.3 3.8 7.2 11.3 1.3 1 0 0 1 1 1 0 FAM176 family PIP5K PF01504.18 CDJ65897.1 - 2.7 7.2 14.8 3.3 6.9 14.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CDC45 PF02724.14 CDJ65897.1 - 2.7 6.2 17.6 3 6.0 17.6 1.0 1 0 0 1 1 1 0 CDC45-like protein LMBR1 PF04791.16 CDJ65897.1 - 3 6.6 8.5 3.2 6.6 8.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Membralin PF09746.9 CDJ65897.1 - 3.5 6.6 11.3 4 6.4 11.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4746 PF15928.5 CDJ65897.1 - 3.6 6.9 13.1 4.9 6.5 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paf1 PF03985.13 CDJ65897.1 - 3.9 6.4 22.8 4.8 6.1 22.8 1.1 1 0 0 1 1 1 0 Paf1 Het-C PF07217.11 CDJ65897.1 - 4.1 5.8 10.7 4.7 5.6 10.7 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Hydin_ADK PF17213.3 CDJ65897.1 - 4.1 7.6 14.8 7.7 6.7 14.8 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain eIF3_subunit PF08597.10 CDJ65897.1 - 4.3 7.2 23.7 5.8 6.8 23.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF2828 PF11443.8 CDJ65897.1 - 4.4 5.3 19.9 5.7 4.9 19.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Pannexin_like PF12534.8 CDJ65897.1 - 4.4 6.3 12.7 5.4 6.0 12.7 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 NARP1 PF12569.8 CDJ65897.1 - 4.7 6.0 20.4 6 5.7 20.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Folate_carrier PF01770.18 CDJ65897.1 - 4.9 5.8 10.9 6.3 5.4 10.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier ALMT PF11744.8 CDJ65897.1 - 5.2 5.8 15.0 7.4 5.3 15.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Ureide_permease PF07168.11 CDJ65897.1 - 5.3 5.7 9.6 6.8 5.3 9.6 1.1 1 0 0 1 1 1 0 Ureide permease Connexin PF00029.19 CDJ65897.1 - 5.4 6.7 16.8 7.5 6.2 16.8 1.1 1 0 0 1 1 1 0 Connexin Cellulose_synt PF03552.14 CDJ65897.1 - 5.7 5.3 7.2 6.8 5.1 7.2 1.1 1 0 0 1 1 1 0 Cellulose synthase Baculo_PP31 PF05311.11 CDJ65897.1 - 5.7 6.3 17.8 7.5 6.0 17.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Tim54 PF11711.8 CDJ65897.1 - 5.8 5.6 19.8 7.7 5.2 19.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 CDJ65897.1 - 6.2 5.9 11.5 8.1 5.6 11.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Kei1 PF08552.11 CDJ65897.1 - 6.5 6.6 14.1 9.8 6.0 14.1 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 HemX PF04375.14 CDJ65897.1 - 6.6 5.9 33.5 8.7 5.5 33.5 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TFB6 PF17110.5 CDJ65897.1 - 7.2 6.3 10.9 10 5.8 10.9 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Glyco_transf_41 PF13844.6 CDJ65897.1 - 7.3 4.9 9.2 8.7 4.6 9.2 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 41 MDM10 PF12519.8 CDJ65897.1 - 7.7 5.3 17.0 9.3 5.0 17.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 V_ATPase_I PF01496.19 CDJ65897.1 - 8 4.2 20.8 10 3.9 20.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Asparaginase_2 PF01112.18 CDJ65897.1 - 9.4 5.2 11.2 14 4.6 11.2 1.2 1 0 0 1 1 1 0 Asparaginase DUF4407 PF14362.6 CDJ65897.1 - 9.4 5.5 25.6 1.9 7.8 20.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4638 PF15472.6 CDJ65897.1 - 9.5 5.9 17.8 12 5.5 17.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Paramyxo_ncap PF00973.19 CDJ65897.1 - 9.9 4.9 13.3 12 4.7 13.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ThiF PF00899.21 CDJ65898.1 - 0.0033 16.8 0.1 0.0033 16.8 0.1 1.9 2 0 0 2 2 2 1 ThiF family Thioredoxin PF00085.20 CDJ65899.1 - 4.4e-44 148.7 0.3 7.4e-21 74.1 0.6 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 CDJ65899.1 - 1e-07 32.0 0.8 0.0012 19.0 0.1 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CDJ65899.1 - 1.8e-07 31.4 0.0 0.039 14.3 0.0 3.5 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.6 CDJ65899.1 - 2.5e-07 30.5 0.7 0.0017 18.1 0.2 2.3 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 CDJ65899.1 - 4.6e-05 23.4 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_2 PF13098.6 CDJ65899.1 - 6.1e-05 23.4 0.3 0.1 13.0 0.1 3.4 2 1 0 2 2 2 1 Thioredoxin-like domain Apt1 PF10351.9 CDJ65899.1 - 0.00027 19.9 2.2 0.00051 19.0 2.2 1.4 1 1 0 1 1 1 1 Golgi-body localisation protein domain AhpC-TSA PF00578.21 CDJ65899.1 - 0.00034 20.5 0.8 0.53 10.2 0.1 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.6 CDJ65899.1 - 0.0012 18.8 0.0 0.0048 16.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain TraF PF13728.6 CDJ65899.1 - 0.0019 18.0 14.6 1.8 8.4 0.0 3.0 2 1 0 2 2 2 2 F plasmid transfer operon protein IL2 PF00715.17 CDJ65899.1 - 0.025 14.5 1.2 1.1 9.2 0.0 2.7 2 1 0 2 2 2 0 Interleukin 2 OST3_OST6 PF04756.13 CDJ65899.1 - 0.032 13.6 4.8 0.58 9.4 0.0 2.7 3 1 0 3 3 2 0 OST3 / OST6 family, transporter family CNDH2_M PF16869.5 CDJ65899.1 - 0.037 14.7 7.9 0.44 11.2 1.2 2.2 2 0 0 2 2 2 0 PF16858 FAM76 PF16046.5 CDJ65899.1 - 0.054 12.9 6.7 1.3 8.3 2.2 2.1 2 0 0 2 2 2 0 FAM76 protein XRN_N PF03159.18 CDJ65899.1 - 0.22 10.9 1.9 0.35 10.3 1.9 1.4 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DUF4175 PF13779.6 CDJ65899.1 - 0.49 8.2 12.1 0.68 7.8 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SR-25 PF10500.9 CDJ65899.1 - 0.71 9.4 29.1 0.077 12.6 17.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SSP160 PF06933.11 CDJ65899.1 - 1.2 7.3 10.5 1.5 6.9 10.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAM60A PF15396.6 CDJ65899.1 - 1.4 8.9 9.1 1.2 9.1 0.3 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Pex14_N PF04695.13 CDJ65899.1 - 1.8 9.2 18.7 9.8 6.8 0.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDE_Tnp_1_2 PF13586.6 CDJ65899.1 - 2.3 8.6 6.0 2e+02 2.4 5.2 3.1 2 1 0 2 2 2 0 Transposase DDE domain Secretin_N_2 PF07655.13 CDJ65899.1 - 4.8 7.8 19.4 0.2 12.2 10.4 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain NPR3 PF03666.13 CDJ65899.1 - 5.9 5.6 10.8 3.1 6.5 1.1 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4834 PF16118.5 CDJ65899.1 - 6.1 7.9 17.7 5.5 8.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ65899.1 - 8.5 5.2 30.4 0.35 9.8 19.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Rxt3 PF08642.10 CDJ65899.1 - 8.6 7.1 7.9 39 5.0 3.1 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 MscS_TM PF12794.7 CDJ65899.1 - 8.9 5.1 7.9 14 4.4 7.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RAP1 PF07218.11 CDJ65899.1 - 9.5 4.4 10.3 12 4.1 10.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LUC7 PF03194.15 CDJ65900.1 - 1.3e-36 126.5 0.1 1.3e-36 126.5 0.1 2.8 2 0 0 2 2 2 1 LUC7 N_terminus QRPTase_C PF01729.19 CDJ65900.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain RabGAP-TBC PF00566.18 CDJ65901.1 - 4.8e-17 62.3 0.0 5.8e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Antimicrobial14 PF08109.11 CDJ65901.1 - 0.091 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Lactocin 705 family Kp4 PF09044.10 CDJ65902.1 - 0.27 11.3 4.6 0.3 11.2 4.6 1.1 1 0 0 1 1 1 0 Kp4 DUF3446 PF11928.8 CDJ65902.1 - 8.2 6.8 11.9 8 6.8 11.1 1.4 1 1 0 1 1 1 0 Early growth response N-terminal domain ERCC3_RAD25_C PF16203.5 CDJ65905.1 - 0.0046 16.2 3.0 0.0073 15.5 3.0 1.4 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Roughex PF06020.11 CDJ65905.1 - 0.49 9.4 7.6 0.67 9.0 7.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ65905.1 - 1.4 8.9 19.6 2 8.4 19.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CDJ65905.1 - 1.9 7.8 6.8 2.9 7.1 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-RanBP PF00641.18 CDJ65906.1 - 5.5e-06 25.6 6.6 7.7e-06 25.1 6.6 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Spt20 PF12090.8 CDJ65906.1 - 4.4e-05 23.2 10.9 5e-05 23.0 10.9 1.2 1 0 0 1 1 1 1 Spt20 family Med15 PF09606.10 CDJ65906.1 - 6e-05 22.0 3.2 6e-05 22.0 3.2 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ65906.1 - 0.0067 16.5 20.7 0.0076 16.3 20.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Neuregulin PF02158.15 CDJ65906.1 - 0.49 9.7 18.1 0.71 9.2 18.1 1.2 1 0 0 1 1 1 0 Neuregulin intracellular region Apt1 PF10351.9 CDJ65906.1 - 1.7 7.4 15.5 2.1 7.1 15.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-ribbon_3 PF13248.6 CDJ65906.1 - 2.3 7.7 5.2 16 5.1 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Androgen_recep PF02166.16 CDJ65906.1 - 4.9 5.9 19.8 6.9 5.4 19.8 1.2 1 0 0 1 1 1 0 Androgen receptor Activator_LAG-3 PF11498.8 CDJ65906.1 - 7.1 5.5 25.1 12 4.8 25.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SDA1 PF05285.12 CDJ65907.1 - 0.024 14.1 14.2 0.036 13.5 14.2 1.2 1 0 0 1 1 1 0 SDA1 GREB1 PF15782.5 CDJ65907.1 - 0.78 6.8 7.4 0.87 6.6 7.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2722 PF10846.8 CDJ65907.1 - 1.5 7.7 34.5 0.013 14.5 19.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Merozoite_SPAM PF07133.11 CDJ65907.1 - 2.1 8.3 18.0 3.5 7.6 18.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Plasmodium_Vir PF05795.11 CDJ65907.1 - 2.9 7.2 7.7 4.8 6.5 7.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SLC12 PF03522.15 CDJ65907.1 - 6.5 5.7 14.1 11 5.0 14.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 SMYLE_N PF18615.1 CDJ65908.1 - 0.12 11.9 7.3 0.14 11.7 7.3 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain MFS_MOT1 PF16983.5 CDJ65908.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Molybdate transporter of MFS superfamily DUF3141 PF11339.8 CDJ65908.1 - 0.19 10.1 4.9 0.22 9.9 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DUF4820 PF16091.5 CDJ65908.1 - 0.2 11.0 7.3 0.29 10.4 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DivIC PF04977.15 CDJ65908.1 - 0.21 11.4 19.1 0.12 12.2 7.0 2.1 2 0 0 2 2 2 0 Septum formation initiator Menin PF05053.13 CDJ65908.1 - 0.35 9.2 10.9 0.4 9.0 10.9 1.0 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 CDJ65908.1 - 2.6 6.7 14.2 2.8 6.6 14.2 1.0 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ65908.1 - 3.4 6.6 10.0 3.9 6.4 10.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4647 PF15504.6 CDJ65908.1 - 5.1 6.1 15.6 6.8 5.7 15.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) CDK2AP PF09806.9 CDJ65908.1 - 5.6 7.0 15.6 7.1 6.6 15.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Hid1 PF12722.7 CDJ65908.1 - 5.7 4.9 11.4 6.3 4.8 11.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4569 PF15133.6 CDJ65908.1 - 7.1 6.3 12.3 8.8 6.0 12.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF4407 PF14362.6 CDJ65908.1 - 7.4 5.8 13.2 9.4 5.5 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dynamin_N PF00350.23 CDJ65908.1 - 8.7 6.4 7.5 23 5.0 7.5 1.7 1 1 0 1 1 1 0 Dynamin family MSL1_dimer PF16801.5 CDJ65910.1 - 1.8 8.4 6.9 3.9 7.3 6.9 1.5 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 Mpv17_PMP22 PF04117.12 CDJ65912.1 - 1.6e-11 44.3 0.3 1.6e-11 44.3 0.3 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Neur_chan_memb PF02932.16 CDJ65912.1 - 0.1 12.6 13.6 0.1 12.6 2.4 2.5 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PepSY_TM_like_2 PF16357.5 CDJ65912.1 - 0.11 12.5 2.7 0.95 9.4 0.1 2.5 2 0 0 2 2 2 0 Putative PepSY_TM-like Kelch_4 PF13418.6 CDJ65913.1 - 7.6e-06 25.8 0.0 2.4e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ65913.1 - 4.3e-05 23.6 0.6 0.00067 19.9 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 CDJ65913.1 - 0.00027 20.8 0.1 0.0032 17.4 0.0 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CDJ65913.1 - 0.0095 16.2 3.9 0.077 13.3 0.1 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CDJ65913.1 - 0.0099 15.4 0.0 0.03 13.9 0.0 1.9 1 0 0 1 1 1 1 Kelch motif PAM2 PF07145.15 CDJ65913.1 - 0.011 15.4 0.3 0.022 14.4 0.3 1.4 1 0 0 1 1 1 0 Ataxin-2 C-terminal region PIG-H PF10181.9 CDJ65914.1 - 2.4e-11 43.3 0.7 4.4e-11 42.5 0.7 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component KASH PF10541.9 CDJ65914.1 - 0.26 11.6 3.0 0.26 11.6 0.5 2.3 2 0 0 2 2 2 0 Nuclear envelope localisation domain RNA_pol_Rpb1_5 PF04998.17 CDJ65915.1 - 1.4e-100 336.2 0.2 2e-100 335.7 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CDJ65915.1 - 9.1e-95 317.6 0.0 1.8e-94 316.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CDJ65915.1 - 1.2e-74 250.0 0.0 2.7e-74 248.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CDJ65915.1 - 4.3e-48 163.7 4.5 7.5e-48 162.9 4.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CDJ65915.1 - 7.2e-48 162.0 1.6 1.6e-47 160.9 1.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CDJ65915.1 - 9.2e-44 149.1 0.0 2.8e-43 147.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CDJ65915.1 - 5e-39 132.6 0.2 5e-39 132.6 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 CDJ65915.1 - 0.004 17.4 10.3 0.004 17.4 10.3 13.0 11 2 1 13 13 13 6 RNA polymerase Rpb1 C-terminal repeat LSM PF01423.22 CDJ65916.1 - 5.1e-16 58.1 0.4 6.3e-16 57.8 0.4 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDJ65916.1 - 0.038 13.6 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 CDJ65916.1 - 0.063 13.4 0.0 0.075 13.2 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain RCC1 PF00415.18 CDJ65917.1 - 1.4e-32 112.1 12.3 9.8e-09 35.7 0.2 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ65917.1 - 2.3e-16 59.1 20.8 4.6e-06 26.3 0.1 4.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat DUF1664 PF07889.12 CDJ65917.1 - 0.0026 17.8 6.4 0.0026 17.8 6.4 7.4 4 1 6 10 10 10 3 Protein of unknown function (DUF1664) UQ_con PF00179.26 CDJ65918.1 - 1.4e-44 151.2 0.0 1.8e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 CDJ65918.1 - 3.2e-07 30.1 0.0 5.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 CDJ65918.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ65918.1 - 0.0088 16.3 0.1 0.019 15.2 0.0 1.6 2 0 0 2 2 2 1 RWD domain UFC1 PF08694.11 CDJ65918.1 - 0.083 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UCR_14kD PF02271.16 CDJ65920.1 - 1.3e-21 76.4 0.1 1.9e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit SR-25 PF10500.9 CDJ65920.1 - 2.6 7.6 7.6 3.6 7.1 7.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rsm22 PF09243.10 CDJ65921.1 - 1.7e-52 178.4 10.6 1.7e-34 119.4 0.3 4.1 4 1 0 4 4 4 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 CDJ65921.1 - 1.3e-06 28.4 0.0 3.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ65921.1 - 0.00035 21.2 0.0 0.0014 19.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ65921.1 - 0.001 19.8 0.3 0.0028 18.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Spt20 PF12090.8 CDJ65921.1 - 0.0011 18.6 12.2 0.0012 18.5 1.5 2.4 2 0 0 2 2 2 1 Spt20 family SPX PF03105.19 CDJ65921.1 - 0.0029 17.6 8.5 0.0029 17.6 8.5 3.1 3 0 0 3 3 3 1 SPX domain TFIIA PF03153.13 CDJ65921.1 - 0.0037 17.3 1.7 0.0037 17.3 1.7 3.6 3 1 0 3 3 2 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ65921.1 - 0.0092 16.3 11.0 0.0092 16.3 11.0 6.0 3 2 2 5 5 3 1 Anti-sigma-K factor rskA NAM-associated PF14303.6 CDJ65921.1 - 0.03 15.0 0.0 0.03 15.0 0.0 4.2 4 1 0 4 4 3 0 No apical meristem-associated C-terminal domain Lipin_mid PF16876.5 CDJ65921.1 - 0.039 14.1 0.1 0.22 11.7 0.3 2.1 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Apt1 PF10351.9 CDJ65921.1 - 1.6 7.5 28.1 0.62 8.8 4.5 2.5 3 0 0 3 3 3 0 Golgi-body localisation protein domain zf-Tim10_DDP PF02953.15 CDJ65922.1 - 1.1e-09 37.7 0.1 2.1e-09 36.9 0.1 1.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_60s PF00428.19 CDJ65922.1 - 0.18 12.4 11.6 0.28 11.8 11.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ65923.1 - 0.0012 18.5 2.3 0.0012 18.5 2.3 4.6 4 1 0 4 4 4 2 Spt20 family RskA PF10099.9 CDJ65923.1 - 0.0035 17.6 7.5 0.0035 17.6 7.5 6.2 2 1 4 6 6 6 1 Anti-sigma-K factor rskA IMUP PF15761.5 CDJ65924.1 - 0.27 11.9 30.6 0.042 14.6 10.5 2.6 1 1 1 2 2 2 0 Immortalisation up-regulated protein ANAPC3 PF12895.7 CDJ65925.1 - 4.6e-05 23.6 5.5 0.0023 18.1 0.8 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CDJ65925.1 - 0.00049 20.1 0.3 0.064 13.5 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ65925.1 - 0.00051 19.9 3.3 0.062 13.4 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Dicty_REP PF05086.12 CDJ65925.1 - 0.002 16.2 14.4 0.0034 15.5 14.4 1.3 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein TPR_6 PF13174.6 CDJ65925.1 - 0.017 15.7 14.0 0.56 11.0 0.0 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ65925.1 - 0.21 11.8 8.1 1 9.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat GREB1 PF15782.5 CDJ65925.1 - 0.23 8.5 41.0 0.047 10.8 32.5 2.2 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Peroxin-13_N PF04088.13 CDJ65926.1 - 0.00016 22.0 5.7 0.00016 22.0 5.7 2.3 2 0 0 2 2 2 1 Peroxin 13, N-terminal region PBP1_TM PF14812.6 CDJ65926.1 - 0.0027 18.0 3.0 0.0027 18.0 3.0 2.1 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 CDJ65926.1 - 0.0098 15.7 21.7 0.012 15.4 21.7 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Presenilin PF01080.17 CDJ65926.1 - 0.036 12.9 30.6 0.048 12.4 30.6 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CDJ65926.1 - 0.28 9.4 23.3 0.33 9.2 23.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 CDJ65926.1 - 0.37 10.7 25.7 0.42 10.5 25.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CD20 PF04103.15 CDJ65926.1 - 1.8 8.6 7.1 0.075 13.1 0.7 1.8 2 0 0 2 2 2 0 CD20-like family MDM10 PF12519.8 CDJ65926.1 - 2.5 6.9 24.2 3.3 6.5 24.2 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SLC12 PF03522.15 CDJ65926.1 - 2.5 7.0 29.3 3.1 6.7 29.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CPSF100_C PF13299.6 CDJ65926.1 - 2.8 8.1 25.3 0.039 14.1 11.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Afi1 PF07792.12 CDJ65926.1 - 5.2 7.5 26.0 0.11 12.9 12.9 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_M56 PF05569.11 CDJ65926.1 - 7.8 5.6 8.7 11 5.1 8.7 1.3 1 1 0 1 1 1 0 BlaR1 peptidase M56 XRN_M PF17846.1 CDJ65926.1 - 8.4 5.2 21.0 9.8 5.0 21.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain CSRNP_N PF16019.5 CDJ65926.1 - 8.9 6.2 27.6 1 9.2 17.8 2.0 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF3408 PF11888.8 CDJ65926.1 - 9.1 6.4 30.6 0.33 11.1 15.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) EFTUD2 PF16004.5 CDJ65926.1 - 9.5 6.8 33.4 0.38 11.4 18.6 2.1 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Sporozoite_P67 PF05642.11 CDJ65927.1 - 1.1 7.2 4.7 1.4 6.9 4.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen IMUP PF15761.5 CDJ65927.1 - 1.3 9.8 20.0 4.4 8.1 10.8 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein WD40 PF00400.32 CDJ65929.1 - 5.7e-05 23.8 0.8 0.097 13.6 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat FAM199X PF15814.5 CDJ65929.1 - 0.00068 18.8 5.4 0.0011 18.2 5.4 1.3 1 0 0 1 1 1 1 Protein family FAM199X DUF2853 PF11015.8 CDJ65929.1 - 0.024 15.3 0.1 0.045 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) RAP1 PF07218.11 CDJ65929.1 - 0.29 9.3 4.6 0.39 9.0 4.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Dmrt1 PF12374.8 CDJ65929.1 - 1.2 9.7 0.1 1.2 9.7 0.1 2.9 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 RskA PF10099.9 CDJ65929.1 - 1.5 9.1 19.3 0.47 10.7 1.6 3.1 3 0 0 3 3 3 0 Anti-sigma-K factor rskA DUF3446 PF11928.8 CDJ65929.1 - 3.8 7.9 19.3 0.52 10.7 13.1 2.6 3 0 0 3 3 3 0 Early growth response N-terminal domain TFIIA PF03153.13 CDJ65929.1 - 5 7.0 9.5 5.4 6.9 8.5 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LisH PF08513.11 CDJ65930.1 - 0.0002 21.2 0.1 0.00054 19.8 0.1 1.8 1 0 0 1 1 1 1 LisH GET2 PF08690.10 CDJ65931.1 - 0.32 10.6 13.1 0.14 11.8 0.3 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 NPR1_interact PF15699.5 CDJ65931.1 - 3 8.5 7.9 2.1 9.0 1.5 2.6 2 0 0 2 2 2 0 NPR1 interacting SR-25 PF10500.9 CDJ65932.1 - 0.00028 20.6 16.9 0.00028 20.6 16.9 4.8 2 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein IF-2B PF01008.17 CDJ65933.1 - 8.7e-11 41.5 2.2 8.7e-11 41.5 2.2 2.5 2 1 0 2 2 2 1 Initiation factor 2 subunit family Dehydrin PF00257.19 CDJ65933.1 - 8.2 7.0 5.7 10 6.6 5.7 1.3 1 0 0 1 1 1 0 Dehydrin Ribosomal_S13_N PF08069.12 CDJ65935.1 - 3.7e-26 90.9 0.0 7.3e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CDJ65935.1 - 1.7e-14 53.8 0.8 2.6e-14 53.2 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 CRAL_TRIO PF00650.20 CDJ65936.1 - 1.6e-18 66.9 0.0 3.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ65936.1 - 1.2e-05 25.5 0.0 2.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain EPL1 PF10513.9 CDJ65936.1 - 0.016 15.6 0.1 0.016 15.6 0.1 2.4 1 1 0 2 2 2 0 Enhancer of polycomb-like BAALC_N PF06989.12 CDJ65936.1 - 0.045 14.1 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 BAALC N-terminus Hamartin PF04388.12 CDJ65937.1 - 0.27 9.9 30.2 0.34 9.5 30.2 1.1 1 0 0 1 1 1 0 Hamartin protein Presenilin PF01080.17 CDJ65937.1 - 0.48 9.1 30.0 0.012 14.4 7.3 2.2 2 0 0 2 2 2 0 Presenilin DUF4549 PF15082.6 CDJ65938.1 - 0.16 11.7 3.7 0.34 10.7 3.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4549) DUF724 PF05266.14 CDJ65938.1 - 1.4 8.7 13.2 0.22 11.3 8.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 CDJ65938.1 - 1.8 9.1 26.5 3.9 8.0 14.1 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3138 PF11336.8 CDJ65938.1 - 6.7 5.2 15.0 4.9 5.6 8.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) CENP-H PF05837.12 CDJ65938.1 - 9 6.7 19.7 9.7 6.6 7.6 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ThiF PF00899.21 CDJ65939.1 - 6.2e-48 163.3 3.3 9.1e-24 84.1 0.4 2.5 2 0 0 2 2 2 2 ThiF family UAE_UbL PF14732.6 CDJ65939.1 - 2.9e-08 34.2 0.0 6.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain SR-25 PF10500.9 CDJ65939.1 - 1.2e-05 25.1 17.1 1.2e-05 25.1 17.1 5.4 3 2 2 5 5 4 1 Nuclear RNA-splicing-associated protein LUC7 PF03194.15 CDJ65939.1 - 0.00083 19.1 5.8 0.00083 19.1 5.8 1.9 2 0 0 2 2 2 1 LUC7 N_terminus DUF2076 PF09849.9 CDJ65939.1 - 0.0023 18.1 12.0 0.0023 18.1 12.0 5.7 5 1 1 6 6 5 1 Uncharacterized protein conserved in bacteria (DUF2076) IMUP PF15761.5 CDJ65939.1 - 0.0091 16.7 2.9 0.0091 16.7 2.9 6.3 4 3 1 5 5 3 1 Immortalisation up-regulated protein Shikimate_DH PF01488.20 CDJ65939.1 - 0.027 14.5 0.7 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MAT1 PF06391.13 CDJ65939.1 - 0.18 11.6 26.7 0.16 11.7 18.9 3.0 3 0 0 3 3 3 0 CDK-activating kinase assembly factor MAT1 TrkA_N PF02254.18 CDJ65939.1 - 0.22 11.8 2.9 0.53 10.6 0.6 2.6 1 1 1 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 CDJ65939.1 - 0.23 12.0 0.2 0.46 11.1 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.15 CDJ65939.1 - 0.54 9.3 0.0 0.54 9.3 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein BAF1_ABF1 PF04684.13 CDJ65939.1 - 1.4 7.9 19.4 1.4 7.9 4.0 2.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ65939.1 - 3.7 6.2 23.6 2.3 6.9 10.3 2.6 2 0 0 2 2 2 0 Presenilin DUF2371 PF10177.9 CDJ65939.1 - 4.6 7.4 7.7 13 5.9 3.8 2.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Choline_kinase PF01633.20 CDJ65940.1 - 2.9e-32 112.0 0.0 1.3e-31 109.8 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CDJ65940.1 - 4.5e-13 49.7 0.1 4.5e-13 49.7 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family EcKinase PF02958.20 CDJ65940.1 - 0.0091 15.3 0.1 0.031 13.6 0.0 1.9 2 0 0 2 2 2 1 Ecdysteroid kinase DUF2722 PF10846.8 CDJ65940.1 - 0.029 13.3 16.6 0.051 12.5 16.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ65940.1 - 0.08 13.2 39.8 0.068 13.5 12.2 3.2 2 1 1 3 3 3 0 Anti-sigma-K factor rskA YdjM PF04307.14 CDJ65940.1 - 0.098 12.0 5.4 1 8.6 2.3 2.4 2 0 0 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase DUF4401 PF14351.6 CDJ65940.1 - 0.22 10.8 4.7 0.42 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) FIST PF08495.10 CDJ65940.1 - 0.46 10.5 2.6 3.5 7.6 2.6 2.4 1 1 0 1 1 1 0 FIST N domain Lin-8 PF03353.15 CDJ65940.1 - 1.3 8.5 9.5 2.1 7.8 9.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.13 CDJ65940.1 - 1.3 8.8 4.9 2.1 8.1 4.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF5349 PF17298.2 CDJ65940.1 - 1.4 8.6 12.7 2.5 7.8 12.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5349) UPF0560 PF10577.9 CDJ65940.1 - 1.7 7.0 10.5 2.7 6.4 10.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MIIP PF15734.5 CDJ65940.1 - 2.8 7.3 11.6 5.1 6.5 11.6 1.4 1 0 0 1 1 1 0 Migration and invasion-inhibitory Ndc1_Nup PF09531.10 CDJ65940.1 - 3.2 6.3 9.3 4.9 5.7 9.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Velvet PF11754.8 CDJ65940.1 - 4.1 7.3 11.2 7 6.5 11.2 1.4 1 0 0 1 1 1 0 Velvet factor DUF3464 PF11947.8 CDJ65940.1 - 7.6 6.3 7.2 1.1 9.1 3.0 1.8 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 SAGA-Tad1 PF12767.7 CDJ65941.1 - 0.00029 20.7 4.4 0.00039 20.2 4.4 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit ESM4 PF15952.5 CDJ65941.1 - 0.002 18.6 12.1 0.15 12.5 2.2 2.2 2 0 0 2 2 2 2 Enhancer of split M4 family Spt20 PF12090.8 CDJ65941.1 - 0.0045 16.6 22.9 0.067 12.8 6.4 2.2 2 0 0 2 2 2 2 Spt20 family TMEM208_SND2 PF05620.11 CDJ65941.1 - 0.014 15.2 1.8 0.014 15.2 1.8 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Activator_LAG-3 PF11498.8 CDJ65941.1 - 0.068 12.1 33.0 0.094 11.7 9.1 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF2722 PF10846.8 CDJ65941.1 - 0.58 9.0 22.0 0.13 11.1 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TMEM51 PF15345.6 CDJ65941.1 - 1.2 8.9 12.2 1.1 9.0 0.4 2.5 2 0 0 2 2 2 0 Transmembrane protein 51 Pap_E4 PF02711.14 CDJ65941.1 - 1.3 10.1 11.2 0.71 10.9 1.7 2.2 2 0 0 2 2 2 0 E4 protein Med31 PF05669.12 CDJ65941.1 - 1.4 9.0 6.1 0.28 11.2 2.5 1.7 2 0 0 2 2 2 0 SOH1 DUF3371 PF11851.8 CDJ65941.1 - 2.2 9.4 10.8 3.3 8.8 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) RskA PF10099.9 CDJ65941.1 - 5 7.4 55.4 0.32 11.3 23.7 3.4 1 1 2 3 3 3 0 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ65941.1 - 7 7.7 9.7 5.5 8.0 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1645 PF07816.11 CDJ65942.1 - 0.015 15.9 7.9 0.015 15.9 7.9 10.3 5 1 3 8 8 8 0 Protein of unknown function (DUF1645) DUF2722 PF10846.8 CDJ65943.1 - 0.0019 17.2 13.5 0.0019 17.2 13.5 17.1 8 5 2 13 13 13 1 Protein of unknown function (DUF2722) Cytochrom_C_asm PF01578.20 CDJ65943.1 - 0.98 9.1 3.7 0.36 10.5 0.1 2.3 2 0 0 2 2 2 0 Cytochrome C assembly protein RRN3 PF05327.11 CDJ65944.1 - 1.3e-21 76.8 0.5 1.5e-21 76.6 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF1539 PF07560.11 CDJ65944.1 - 0.048 13.8 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) NAD_binding_4 PF07993.12 CDJ65944.1 - 0.058 12.5 0.1 0.088 12.0 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein OAD_gamma PF04277.13 CDJ65944.1 - 8.1 7.1 15.9 21 5.8 9.8 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain TFIIA PF03153.13 CDJ65945.1 - 0.0085 16.1 43.8 0.012 15.6 43.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDV3 PF15359.6 CDJ65946.1 - 0.033 14.7 3.7 0.033 14.7 3.7 1.5 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 SUIM_assoc PF16619.5 CDJ65946.1 - 3.5 7.8 9.2 0.6 10.2 4.6 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MAJIN PF15077.6 CDJ65947.1 - 0.027 14.3 8.0 0.032 14.0 8.0 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein V_ATPase_I PF01496.19 CDJ65947.1 - 0.04 11.8 15.2 0.041 11.8 15.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Radical_SAM_N PF08497.10 CDJ65947.1 - 0.35 10.1 6.7 0.38 9.9 6.7 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal XRN_M PF17846.1 CDJ65947.1 - 0.38 9.7 13.8 0.46 9.4 13.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain SID-1_RNA_chan PF13965.6 CDJ65947.1 - 0.5 8.7 5.9 0.53 8.6 5.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.7 CDJ65947.1 - 1 7.4 23.7 12 3.9 0.0 2.6 2 1 0 2 2 2 0 High-temperature-induced dauer-formation protein AUX_IAA PF02309.16 CDJ65947.1 - 1.1 9.0 11.6 1.3 8.8 11.6 1.1 1 0 0 1 1 1 0 AUX/IAA family Neur_chan_memb PF02932.16 CDJ65947.1 - 1.6 8.7 15.1 2.1 8.3 15.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ65947.1 - 2.9 6.6 27.7 3.8 6.2 27.7 1.1 1 0 0 1 1 1 0 Presenilin FliP PF00813.20 CDJ65947.1 - 2.9 7.7 12.9 5 7.0 12.9 1.3 1 0 0 1 1 1 0 FliP family MMR1 PF08505.10 CDJ65947.1 - 3 8.1 27.2 4.4 7.5 27.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Exonuc_VII_L PF02601.15 CDJ65947.1 - 3.4 7.1 25.2 4.2 6.8 25.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YfhO PF09586.10 CDJ65947.1 - 4.2 5.5 13.6 4.5 5.4 13.6 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO FAM60A PF15396.6 CDJ65947.1 - 4.5 7.2 19.8 5.9 6.8 19.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Pkinase PF00069.25 CDJ65948.1 - 8.9e-52 176.1 0.0 2.3e-48 164.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ65948.1 - 1e-29 103.6 0.0 2.2e-29 102.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RskA PF10099.9 CDJ65948.1 - 0.00024 21.5 8.4 0.00047 20.5 8.4 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Kinase-like PF14531.6 CDJ65948.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Sec3_C PF09763.9 CDJ65948.1 - 0.014 13.8 0.0 0.02 13.3 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 TFIIA PF03153.13 CDJ65948.1 - 0.036 14.1 3.0 0.059 13.4 3.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ65948.1 - 0.051 13.2 5.5 0.12 12.0 5.5 1.5 1 0 0 1 1 1 0 Spt20 family Macoilin PF09726.9 CDJ65948.1 - 0.063 11.8 3.4 0.093 11.3 3.4 1.3 1 0 0 1 1 1 0 Macoilin family DUF4834 PF16118.5 CDJ65948.1 - 0.28 12.2 1.3 8.5 7.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Sporozoite_P67 PF05642.11 CDJ65948.1 - 8.6 4.3 9.0 12 3.8 9.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PT PF04886.12 CDJ65949.1 - 0.0003 20.2 35.4 0.0019 17.7 15.6 9.6 5 3 3 8 8 8 3 PT repeat Sporozoite_P67 PF05642.11 CDJ65949.1 - 0.00072 17.8 0.0 0.00072 17.8 0.0 2.6 1 1 1 2 2 2 1 Sporozoite P67 surface antigen TFIIA PF03153.13 CDJ65949.1 - 0.079 12.9 23.5 0.14 12.1 23.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ebp2 PF05890.12 CDJ65951.1 - 4.9e-32 111.6 14.7 7.1e-32 111.0 14.7 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Ribosomal_60s PF00428.19 CDJ65951.1 - 2.6 8.7 35.5 0.24 12.0 2.9 4.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein SR-25 PF10500.9 CDJ65952.1 - 8.5e-07 28.8 65.0 1.9e-06 27.7 29.3 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein BatD PF13584.6 CDJ65952.1 - 0.0012 17.8 4.8 0.0012 17.8 4.8 1.9 1 1 0 1 1 1 1 Oxygen tolerance SRP-alpha_N PF04086.13 CDJ65952.1 - 0.0015 18.5 24.4 0.0015 18.5 24.4 2.2 1 1 1 2 2 1 1 Signal recognition particle, alpha subunit, N-terminal Orf78 PF06024.12 CDJ65952.1 - 0.0026 18.0 0.2 0.0026 18.0 0.2 3.0 2 1 0 2 2 2 1 Orf78 (ac78) DUF2956 PF11169.8 CDJ65952.1 - 0.0065 16.6 7.2 0.0065 16.6 7.2 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2956) DUF2207 PF09972.9 CDJ65952.1 - 0.063 12.0 0.1 0.12 11.1 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BBS2_N PF14781.6 CDJ65952.1 - 0.089 12.7 2.2 0.3 11.0 2.2 1.8 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Sarcoglycan_2 PF05510.13 CDJ65952.1 - 0.097 11.4 2.5 0.14 10.9 2.5 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Renin_r PF07850.14 CDJ65952.1 - 0.11 13.1 0.0 0.11 13.1 0.0 2.6 2 1 0 2 2 2 0 Renin receptor-like protein ABC2_membrane_3 PF12698.7 CDJ65952.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein PBP1_TM PF14812.6 CDJ65952.1 - 0.21 12.0 0.3 0.21 12.0 0.3 3.1 4 0 0 4 4 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HCO3_cotransp PF00955.21 CDJ65952.1 - 0.23 10.3 0.2 0.41 9.4 0.2 1.4 1 0 0 1 1 1 0 HCO3- transporter family ODV-E18 PF10717.9 CDJ65952.1 - 0.83 9.6 0.0 0.83 9.6 0.0 2.4 2 0 0 2 2 1 0 Occlusion-derived virus envelope protein ODV-E18 SID-1_RNA_chan PF13965.6 CDJ65952.1 - 1.1 7.6 6.5 0.68 8.3 4.1 1.7 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 RskA PF10099.9 CDJ65952.1 - 6.5 7.0 68.0 1.3 9.3 33.5 3.3 1 1 2 3 3 3 0 Anti-sigma-K factor rskA Endostatin PF06482.11 CDJ65952.1 - 7.5 5.9 19.3 2.7 7.4 6.4 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Ribosomal_L18p PF00861.22 CDJ65953.1 - 1.8e-23 83.1 8.0 6.5e-15 55.5 3.5 2.2 1 1 1 2 2 2 2 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast ERM PF00769.19 CDJ65954.1 - 0.00014 21.8 5.0 0.00014 21.8 5.0 3.3 3 0 0 3 3 3 1 Ezrin/radixin/moesin family DUF3522 PF12036.8 CDJ65955.1 - 3.5e-08 34.0 9.6 0.00022 21.6 0.4 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3522) Presenilin PF01080.17 CDJ65955.1 - 0.0012 17.6 0.6 0.0012 17.6 0.6 4.5 4 0 0 4 4 4 1 Presenilin Pex14_N PF04695.13 CDJ65955.1 - 0.0056 17.3 8.4 0.0056 17.3 8.4 9.1 8 2 1 9 9 9 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ65955.1 - 0.0059 16.4 0.4 0.0059 16.4 0.4 3.9 4 1 0 4 4 4 1 Connexin Peroxin-3 PF04882.12 CDJ65955.1 - 0.042 12.9 0.1 0.042 12.9 0.1 5.5 6 0 0 6 6 6 0 Peroxin-3 TFIIA PF03153.13 CDJ65956.1 - 0.47 10.4 45.2 0.72 9.8 45.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YEATS PF03366.16 CDJ65957.1 - 4.5e-10 39.4 0.0 6.1e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 YEATS family TIR PF01582.20 CDJ65957.1 - 0.093 12.5 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 TIR domain eIF-6 PF01912.18 CDJ65959.1 - 7.8e-76 253.9 0.1 1.1e-75 253.3 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family PP2C PF00481.21 CDJ65961.1 - 8.6e-25 87.8 0.1 5.9e-11 42.5 0.9 2.8 2 0 0 2 2 2 2 Protein phosphatase 2C Linocin_M18 PF04454.12 CDJ65961.1 - 0.2 10.9 1.9 0.41 9.9 1.9 1.5 1 0 0 1 1 1 0 Encapsulating protein for peroxidase DUF818 PF05677.12 CDJ65962.1 - 0.0064 15.5 0.1 0.14 11.1 0.0 2.3 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_1 PF00561.20 CDJ65962.1 - 0.017 14.8 0.1 0.017 14.8 0.1 3.5 3 1 0 3 3 3 0 alpha/beta hydrolase fold TFIIA PF03153.13 CDJ65963.1 - 0.095 12.7 13.2 0.11 12.4 13.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.3 CDJ65963.1 - 0.5 10.6 4.1 0.61 10.3 4.1 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Med3 PF11593.8 CDJ65963.1 - 1.5 7.9 12.4 1.9 7.6 12.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Androgen_recep PF02166.16 CDJ65963.1 - 2.5 6.8 17.5 3 6.6 17.5 1.2 1 0 0 1 1 1 0 Androgen receptor AAA_23 PF13476.6 CDJ65963.1 - 3.5 8.1 13.2 4.3 7.8 13.2 1.1 1 0 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.12 CDJ65963.1 - 3.6 6.4 10.2 4.5 6.1 10.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2489 PF10675.9 CDJ65963.1 - 7 6.6 18.6 3 7.8 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) eIF-3_zeta PF05091.12 CDJ65964.1 - 0.0031 16.6 17.1 0.0032 16.5 17.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ65964.1 - 0.015 13.6 30.6 0.016 13.5 30.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SpoIIP PF07454.11 CDJ65964.1 - 0.019 14.4 11.1 0.021 14.3 11.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CLN3 PF02487.17 CDJ65964.1 - 0.019 14.0 7.3 0.02 14.0 7.3 1.1 1 0 0 1 1 1 0 CLN3 protein Plasmodium_Vir PF05795.11 CDJ65964.1 - 0.023 14.1 4.4 0.025 14.0 4.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lin-8 PF03353.15 CDJ65964.1 - 0.035 13.7 20.3 0.04 13.5 20.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DDHD PF02862.17 CDJ65964.1 - 0.037 14.2 11.4 0.049 13.8 11.4 1.3 1 0 0 1 1 1 0 DDHD domain SelP_N PF04592.14 CDJ65964.1 - 0.038 13.4 14.4 0.047 13.1 14.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIA PF03153.13 CDJ65964.1 - 0.038 14.0 45.8 0.048 13.7 45.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ureide_permease PF07168.11 CDJ65964.1 - 0.043 12.6 4.1 0.053 12.3 4.1 1.2 1 0 0 1 1 1 0 Ureide permease OATP PF03137.20 CDJ65964.1 - 0.063 11.6 4.6 0.073 11.3 4.6 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CDC45 PF02724.14 CDJ65964.1 - 0.074 11.3 12.4 0.078 11.3 12.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 CDJ65964.1 - 0.08 11.7 10.8 0.091 11.5 10.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4192 PF13830.6 CDJ65964.1 - 0.086 12.9 14.0 0.1 12.6 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) NST1 PF13945.6 CDJ65964.1 - 0.097 12.8 19.2 0.13 12.4 19.2 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Suf PF05843.14 CDJ65964.1 - 0.097 12.6 17.9 0.13 12.2 17.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0560 PF10577.9 CDJ65964.1 - 0.098 11.2 19.6 0.1 11.1 19.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SAPS PF04499.15 CDJ65964.1 - 0.13 11.0 10.2 0.15 10.8 10.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 CDJ65964.1 - 0.15 11.1 15.3 0.16 10.9 15.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 TERB2 PF15101.6 CDJ65964.1 - 0.17 11.9 20.3 0.24 11.4 20.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Zip PF02535.22 CDJ65964.1 - 0.17 11.1 6.5 0.19 10.9 6.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 CDJ65964.1 - 0.23 11.2 9.9 0.28 10.9 9.9 1.1 1 0 0 1 1 1 0 Connexin NPR3 PF03666.13 CDJ65964.1 - 0.33 9.7 15.3 0.37 9.5 15.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ALMT PF11744.8 CDJ65964.1 - 0.34 9.7 13.8 0.39 9.5 13.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter O-antigen_lig PF13425.6 CDJ65964.1 - 0.38 9.5 3.1 0.42 9.4 3.1 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Folate_carrier PF01770.18 CDJ65964.1 - 0.39 9.4 7.9 0.47 9.1 7.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier RR_TM4-6 PF06459.12 CDJ65964.1 - 0.4 10.5 17.7 0.48 10.2 17.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 CDJ65964.1 - 0.4 10.0 23.5 0.53 9.6 23.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Serinc PF03348.15 CDJ65964.1 - 0.47 9.3 8.3 0.54 9.1 8.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 CDJ65964.1 - 0.5 9.1 24.0 0.59 8.8 24.0 1.1 1 0 0 1 1 1 0 Presenilin DUF4638 PF15472.6 CDJ65964.1 - 0.51 10.0 13.3 0.66 9.7 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Peptidase_S49_N PF08496.10 CDJ65964.1 - 0.52 10.4 11.4 0.71 9.9 11.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Miga PF10265.9 CDJ65964.1 - 0.54 9.2 16.4 0.66 8.9 16.4 1.1 1 0 0 1 1 1 0 Mitoguardin EOS1 PF12326.8 CDJ65964.1 - 0.57 10.1 8.4 0.75 9.7 8.4 1.4 1 0 0 1 1 1 0 N-glycosylation protein DUF1387 PF07139.11 CDJ65964.1 - 0.65 9.7 19.9 0.79 9.4 19.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CPSF100_C PF13299.6 CDJ65964.1 - 0.66 10.1 14.7 0.88 9.7 14.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2370 PF10176.9 CDJ65964.1 - 0.74 9.4 6.6 0.91 9.1 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Band_3_cyto PF07565.13 CDJ65964.1 - 0.83 9.4 14.9 1 9.1 14.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SID-1_RNA_chan PF13965.6 CDJ65964.1 - 0.88 7.9 7.0 0.99 7.7 7.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ65964.1 - 0.93 9.5 15.8 1.1 9.2 15.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.9 CDJ65964.1 - 0.95 9.5 14.9 1.2 9.2 14.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Peptidase_S15 PF02129.18 CDJ65964.1 - 1 8.9 12.7 1.2 8.6 12.7 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CSG2 PF16965.5 CDJ65964.1 - 1.2 8.0 6.9 1.4 7.8 6.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Membralin PF09746.9 CDJ65964.1 - 1.5 7.8 9.8 1.7 7.6 9.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein FAM176 PF14851.6 CDJ65964.1 - 1.5 8.4 12.7 2.2 7.9 12.7 1.2 1 0 0 1 1 1 0 FAM176 family PA26 PF04636.13 CDJ65964.1 - 1.7 7.5 12.3 2 7.3 12.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Macoilin PF09726.9 CDJ65964.1 - 1.8 7.1 18.8 2 6.9 18.8 1.1 1 0 0 1 1 1 0 Macoilin family DUF3464 PF11947.8 CDJ65964.1 - 1.8 8.3 17.0 2.8 7.7 17.0 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2828 PF11443.8 CDJ65964.1 - 1.9 6.5 16.9 2.2 6.2 16.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) GREB1 PF15782.5 CDJ65964.1 - 2.5 5.1 25.3 2.6 5.1 25.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FliP PF00813.20 CDJ65964.1 - 2.9 7.7 4.6 3.3 7.5 4.6 1.2 1 0 0 1 1 1 0 FliP family CD20 PF04103.15 CDJ65964.1 - 3.4 7.7 5.8 15 5.6 5.8 2.0 1 1 0 1 1 1 0 CD20-like family Sec62 PF03839.16 CDJ65964.1 - 3.5 7.1 12.2 4.3 6.8 12.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 T2SSC PF11356.8 CDJ65964.1 - 3.5 7.5 16.6 6.3 6.7 16.6 1.5 1 0 0 1 1 1 0 Type II secretion system protein C Baculo_PP31 PF05311.11 CDJ65964.1 - 4.7 6.6 15.1 6.3 6.2 15.1 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Hid1 PF12722.7 CDJ65964.1 - 5 5.1 20.1 5.6 5.0 20.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.11 CDJ65964.1 - 5.3 5.4 18.0 5.6 5.3 18.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Pannexin_like PF12534.8 CDJ65964.1 - 5.4 6.0 13.2 6.4 5.8 13.2 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Cellulose_synt PF03552.14 CDJ65964.1 - 5.7 5.3 5.6 6.3 5.2 5.6 1.0 1 0 0 1 1 1 0 Cellulose synthase Paramyxo_ncap PF00973.19 CDJ65964.1 - 6.5 5.6 14.7 7.1 5.4 14.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein 5_nucleotid PF05761.14 CDJ65964.1 - 7.1 5.4 13.7 8.7 5.1 13.7 1.0 1 0 0 1 1 1 0 5' nucleotidase family HCO3_cotransp PF00955.21 CDJ65964.1 - 7.1 5.3 5.9 7.8 5.2 5.9 1.1 1 0 0 1 1 1 0 HCO3- transporter family Gastrin PF00918.17 CDJ65964.1 - 7.4 7.6 18.0 11 7.0 18.0 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF2126 PF09899.9 CDJ65964.1 - 7.4 4.5 13.4 8.3 4.3 13.4 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Spore_coat_CotO PF14153.6 CDJ65964.1 - 8 6.3 24.2 11 5.9 24.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DDRGK PF09756.9 CDJ65964.1 - 9.1 5.8 22.3 13 5.4 22.3 1.2 1 0 0 1 1 1 0 DDRGK domain Otopetrin PF03189.13 CDJ65964.1 - 9.8 4.9 10.9 11 4.7 10.9 1.1 1 0 0 1 1 1 0 Otopetrin DUF2722 PF10846.8 CDJ65965.1 - 0.0018 17.3 5.5 0.0024 16.9 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) S1-P1_nuclease PF02265.16 CDJ65965.1 - 0.0072 16.2 1.7 0.0073 16.2 0.0 1.7 1 1 1 2 2 2 1 S1/P1 Nuclease DUF3605 PF12239.8 CDJ65965.1 - 0.0099 16.2 1.1 0.032 14.6 1.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) Spt20 PF12090.8 CDJ65965.1 - 0.034 13.8 10.2 0.051 13.2 10.2 1.2 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ65965.1 - 0.18 12.8 7.6 1.9 9.5 3.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3824 PF12868.7 CDJ65966.1 - 0.003 18.2 14.7 0.003 18.2 14.7 5.1 3 2 0 3 3 3 1 Domain of unknwon function (DUF3824) 2HCT PF03390.15 CDJ65966.1 - 0.44 9.1 2.6 0.91 8.1 2.6 1.4 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family AAA_23 PF13476.6 CDJ65966.1 - 3.9 7.9 39.9 3.7 8.0 10.5 2.1 2 0 0 2 2 2 0 AAA domain DUF2339 PF10101.9 CDJ65967.1 - 0.41 9.2 9.6 0.48 8.9 9.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) AcetylCoA_hydro PF02550.15 CDJ65967.1 - 0.57 10.1 3.1 6.5 6.7 0.1 2.0 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase N-terminal domain Med15 PF09606.10 CDJ65967.1 - 8.3 4.9 27.2 11 4.6 27.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Queuosine_synth PF02547.15 CDJ65968.1 - 0.067 12.3 1.9 2.7 7.0 0.1 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein DUF4148 PF13663.6 CDJ65968.1 - 5.9 7.1 15.6 8.7 6.6 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Mod_r PF07200.13 CDJ65968.1 - 6.8 6.8 11.8 2.2 8.4 7.7 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CCSAP PF15748.5 CDJ65968.1 - 8.8 6.4 12.2 15 5.6 11.9 1.5 1 1 0 1 1 1 0 Centriole, cilia and spindle-associated SOBP PF15279.6 CDJ65969.1 - 0.0045 17.6 25.6 0.0068 17.1 25.6 1.2 1 0 0 1 1 1 1 Sine oculis-binding protein PAT1 PF09770.9 CDJ65969.1 - 0.0078 14.6 47.9 0.0094 14.3 47.9 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 AF-4 PF05110.13 CDJ65969.1 - 0.041 12.0 27.4 0.047 11.8 27.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein VIR_N PF15912.5 CDJ65969.1 - 0.087 12.4 8.3 0.13 11.8 8.3 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal GREB1 PF15782.5 CDJ65969.1 - 0.11 9.6 23.4 0.13 9.4 23.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Endostatin PF06482.11 CDJ65969.1 - 0.41 10.1 27.1 0.62 9.5 27.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Zip PF02535.22 CDJ65969.1 - 0.42 9.8 7.7 0.56 9.4 7.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.10 CDJ65969.1 - 0.7 8.5 29.7 0.91 8.1 29.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ65969.1 - 1.1 7.9 32.5 1.5 7.5 32.5 1.1 1 0 0 1 1 1 0 Presenilin Exonuc_VII_L PF02601.15 CDJ65969.1 - 1.8 8.1 36.5 2.5 7.6 36.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Draxin PF15550.6 CDJ65969.1 - 1.8 8.4 17.2 2.4 7.9 17.2 1.1 1 0 0 1 1 1 0 Draxin V_ATPase_I PF01496.19 CDJ65969.1 - 4.6 5.0 27.7 5.7 4.7 27.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vfa1 PF08432.10 CDJ65969.1 - 4.7 7.5 27.8 7.6 6.8 27.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CCSAP PF15748.5 CDJ65969.1 - 9.3 6.3 35.3 13 5.9 35.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FtsX PF02687.21 CDJ65970.1 - 0.35 11.4 3.3 5.4 7.6 0.1 2.9 3 0 0 3 3 3 0 FtsX-like permease family Pex14_N PF04695.13 CDJ65971.1 - 0.87 10.2 6.9 6.1 7.5 7.0 2.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PDEase_I PF00233.19 CDJ65972.1 - 1.4e-38 133.0 0.0 1.4e-38 133.0 0.0 2.5 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase SUIM_assoc PF16619.5 CDJ65972.1 - 0.013 15.5 4.3 0.013 15.5 4.3 3.2 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pox_G7 PF05503.12 CDJ65972.1 - 0.049 12.6 0.8 0.084 11.8 0.8 1.3 1 0 0 1 1 1 0 Poxvirus G7-like HD PF01966.22 CDJ65972.1 - 0.16 12.2 0.0 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 HD domain DUF2722 PF10846.8 CDJ65972.1 - 0.58 9.0 27.8 0.17 10.8 17.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Androgen_recep PF02166.16 CDJ65972.1 - 0.7 8.7 21.7 0.024 13.5 6.0 2.1 2 0 0 2 2 2 0 Androgen receptor Hid1 PF12722.7 CDJ65972.1 - 2.7 6.0 22.0 3.9 5.5 22.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2722 PF10846.8 CDJ65973.1 - 3.4e-05 23.0 12.9 3.4e-05 23.0 12.9 3.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) PIG-U PF06728.13 CDJ65973.1 - 0.068 12.2 0.4 0.1 11.7 0.4 1.3 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U DUF1764 PF08576.10 CDJ65973.1 - 3.3 8.6 26.8 0.2 12.5 3.0 2.9 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF4471 PF14740.6 CDJ65973.1 - 5.8 6.0 26.0 0.49 9.6 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) DUF2339 PF10101.9 CDJ65973.1 - 8.8 4.8 48.0 14 4.1 48.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Sporozoite_P67 PF05642.11 CDJ65973.1 - 10 4.1 13.5 13 3.8 13.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPR_2 PF07719.17 CDJ65975.1 - 0.0016 18.4 0.9 0.0016 18.4 0.9 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ65975.1 - 0.0046 16.7 1.9 0.013 15.3 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ65975.1 - 0.046 14.6 2.5 0.046 14.6 2.5 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat RskA PF10099.9 CDJ65975.1 - 0.49 10.7 13.3 1.7 8.9 12.0 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Usp PF00582.26 CDJ65975.1 - 1 9.9 0.0 1 9.9 0.0 2.9 2 1 0 2 2 2 0 Universal stress protein family TPR_19 PF14559.6 CDJ65977.1 - 6.5e-07 29.8 0.8 6.5e-07 29.8 0.8 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat SART-1 PF03343.13 CDJ65977.1 - 0.00072 18.3 2.6 0.00096 17.8 2.6 1.2 1 0 0 1 1 1 1 SART-1 family DUF1645 PF07816.11 CDJ65977.1 - 0.31 11.6 18.2 2 8.9 1.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) Secretin_N_2 PF07655.13 CDJ65977.1 - 3.1 8.4 24.7 0.8 10.3 5.9 3.1 3 0 0 3 3 3 0 Secretin N-terminal domain eIF3g PF12353.8 CDJ65977.1 - 8.9 6.7 8.6 2.8 8.3 3.1 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G MFS_5 PF05631.14 CDJ65979.1 - 1.8e-05 23.9 0.1 1.8e-05 23.9 0.1 2.7 3 0 0 3 3 3 1 Sugar-tranasporters, 12 TM Lin-8 PF03353.15 CDJ65979.1 - 0.0061 16.2 4.5 0.0061 16.2 4.5 2.0 2 0 0 2 2 2 1 Ras-mediated vulval-induction antagonist SelK_SelG PF10961.8 CDJ65979.1 - 0.022 15.4 0.3 8.6 7.1 0.0 2.7 2 0 0 2 2 2 0 Selenoprotein SelK_SelG NAD_kinase PF01513.21 CDJ65979.1 - 0.047 12.9 0.1 0.076 12.2 0.1 1.3 1 0 0 1 1 1 0 ATP-NAD kinase G0-G1_switch_2 PF15103.6 CDJ65979.1 - 0.059 13.8 1.5 0.13 12.7 1.5 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF3446 PF11928.8 CDJ65979.1 - 0.17 12.2 46.8 0.094 13.0 13.0 3.7 3 0 0 3 3 3 0 Early growth response N-terminal domain SUZ PF12752.7 CDJ65979.1 - 1.8 9.3 16.2 0.81 10.5 3.1 2.8 2 0 0 2 2 2 0 SUZ domain Inositol_P PF00459.25 CDJ65979.1 - 2.8 7.4 8.6 0.56 9.7 3.7 2.2 1 1 1 2 2 2 0 Inositol monophosphatase family SPX PF03105.19 CDJ65979.1 - 3.6 7.4 22.7 6.1 6.6 22.7 1.3 1 1 0 1 1 1 0 SPX domain Filament_head PF04732.14 CDJ65979.1 - 9.6 7.2 39.7 20 6.1 18.0 2.7 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region PTH2 PF01981.16 CDJ65980.1 - 9.9 6.5 13.0 0.098 12.9 3.4 2.3 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 Ribosomal_S19 PF00203.21 CDJ65982.1 - 3.1e-30 103.9 0.1 4.2e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Siah-Interact_N PF09032.11 CDJ65983.1 - 5.4e-06 26.6 0.1 1.2e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 Siah interacting protein, N terminal CS PF04969.16 CDJ65983.1 - 0.013 16.6 0.0 0.026 15.6 0.0 1.6 1 0 0 1 1 1 0 CS domain PLU-1 PF08429.11 CDJ65983.1 - 0.014 14.5 1.1 0.018 14.3 0.6 1.4 1 1 0 1 1 1 0 PLU-1-like protein LRR_4 PF12799.7 CDJ65985.1 - 1.5e-15 57.1 17.4 1.9e-06 28.1 2.0 4.2 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ65985.1 - 8.3e-14 51.1 32.6 1.8e-06 27.6 3.8 3.7 2 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 CDJ65985.1 - 6.6e-06 25.7 1.9 0.00077 19.0 0.3 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CDJ65985.1 - 6.7e-06 25.9 13.9 5.2 8.0 0.0 6.5 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 CDJ65985.1 - 2.2e-05 24.2 14.8 1.4 9.1 0.1 6.3 6 0 0 6 6 6 2 Leucine Rich repeat Surp PF01805.20 CDJ65986.1 - 5.8e-09 35.8 0.9 6.5e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 Surp module DRY_EERY PF09750.9 CDJ65986.1 - 6e-09 36.3 0.1 6e-09 36.3 0.1 3.2 2 1 0 2 2 2 1 Alternative splicing regulator SHS2_Rpb7-N PF03876.17 CDJ65987.1 - 3.2e-12 46.6 0.0 5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 polyprenyl_synt PF00348.17 CDJ65988.1 - 2.7e-53 180.6 0.0 3.7e-52 176.9 0.0 2.2 1 1 0 1 1 1 1 Polyprenyl synthetase DUF3780 PF12635.7 CDJ65988.1 - 0.0025 17.6 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3780) adh_short PF00106.25 CDJ65990.1 - 7.6e-27 94.0 0.0 8.7e-21 74.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ65990.1 - 1e-17 64.5 0.0 4.6e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ65990.1 - 5.3e-08 33.0 0.0 5.3e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 KR domain B-block_TFIIIC PF04182.12 CDJ65991.1 - 1.5e-06 28.3 0.0 5.6e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 CDJ65991.1 - 0.021 14.7 0.9 5 7.1 0.0 3.4 3 0 0 3 3 3 0 MarR family HTH_5 PF01022.20 CDJ65991.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Wzy_C PF04932.15 CDJ65994.1 - 0.056 13.1 4.7 0.63 9.7 0.0 3.3 4 0 0 4 4 4 0 O-Antigen ligase G3P_antiterm PF04309.12 CDJ65994.1 - 0.094 12.1 0.0 0.33 10.3 0.0 1.9 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator DUF4064 PF13273.6 CDJ65994.1 - 0.12 12.7 4.0 8.1 6.8 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) DUF4131 PF13567.6 CDJ65994.1 - 0.69 9.5 21.6 0.076 12.7 3.8 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) HSP70 PF00012.20 CDJ65995.1 - 4.5e-264 877.2 7.5 5.3e-264 877.0 7.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ65995.1 - 3.2e-15 55.8 1.9 5.9e-13 48.3 0.3 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CDJ65995.1 - 0.00016 22.1 1.3 2.6 8.5 0.0 3.9 3 1 0 3 3 3 2 Cell division protein FtsA DUF5398 PF17376.2 CDJ65995.1 - 0.0038 17.8 0.7 0.0094 16.5 0.7 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5398) FGGY_C PF02782.16 CDJ65995.1 - 0.023 14.4 0.1 0.062 13.0 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain ATP-synt_B PF00430.18 CDJ65995.1 - 1.4 9.0 8.0 3.2 7.8 8.0 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1090 PF06476.12 CDJ65995.1 - 2 8.6 7.5 4.3 7.5 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) SRP-alpha_N PF04086.13 CDJ65996.1 - 0.0039 17.2 11.5 0.0051 16.8 11.5 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Med19 PF10278.9 CDJ65996.1 - 0.034 14.1 18.3 0.059 13.3 18.3 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4357 PF14267.6 CDJ65996.1 - 0.035 14.0 0.4 0.035 14.0 0.4 2.3 2 0 0 2 2 1 0 Domain of unknown function (DUF4357) FancD2 PF14631.6 CDJ65996.1 - 0.13 9.6 6.0 0.17 9.3 6.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease zinc_ribbon_2 PF13240.6 CDJ65996.1 - 0.27 11.0 2.3 0.62 9.9 2.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DUF3827 PF12877.7 CDJ65996.1 - 0.41 9.0 11.3 0.49 8.7 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TAF4 PF05236.14 CDJ65996.1 - 0.48 10.1 13.4 0.032 14.0 7.1 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Neur_chan_memb PF02932.16 CDJ65996.1 - 0.49 10.4 5.5 0.63 10.1 5.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SWIRM-assoc_2 PF16496.5 CDJ65996.1 - 0.92 8.3 15.2 1.2 7.9 15.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Spem1 PF15670.5 CDJ65996.1 - 1.1 8.7 8.4 1.6 8.2 8.4 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 TFIIF_alpha PF05793.12 CDJ65996.1 - 2.1 6.8 22.0 2.7 6.5 22.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 CDJ65996.1 - 2.3 6.9 8.6 2.9 6.6 8.6 1.1 1 0 0 1 1 1 0 Presenilin NAM-associated PF14303.6 CDJ65996.1 - 2.6 8.7 18.2 4 8.1 18.2 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4614 PF15391.6 CDJ65996.1 - 2.7 7.9 17.5 4.1 7.4 17.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Zip PF02535.22 CDJ65996.1 - 4.5 6.4 6.9 6.4 5.9 6.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DTHCT PF08070.11 CDJ65996.1 - 4.5 8.1 36.1 4 8.2 33.9 1.8 1 1 1 2 2 2 0 DTHCT (NUC029) region Herpes_DNAp_acc PF04929.12 CDJ65996.1 - 4.6 6.1 10.6 6.2 5.7 10.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF5427 PF10310.9 CDJ65996.1 - 7.8 5.3 14.9 11 4.9 14.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Nucleo_P87 PF07267.11 CDJ65996.1 - 8.5 5.1 7.1 11 4.7 7.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RR_TM4-6 PF06459.12 CDJ65996.1 - 9.2 6.0 8.4 12 5.6 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 CDJ65996.1 - 9.7 4.9 17.2 13 4.5 17.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PIG-X PF08320.12 CDJ66000.1 - 1.7e-14 54.3 0.0 1.2e-13 51.5 0.0 2.2 1 1 0 1 1 1 1 PIG-X / PBN1 DUF2391 PF09622.10 CDJ66001.1 - 0.26 10.6 1.6 0.54 9.5 0.0 2.3 3 0 0 3 3 3 0 Putative integral membrane protein (DUF2391) ORC5_C PF14630.6 CDJ66001.1 - 0.51 9.8 3.7 0.33 10.4 0.4 2.2 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus REV PF00424.18 CDJ66001.1 - 3.2 7.8 14.2 0.36 10.9 0.9 3.9 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) RNase_Zc3h12a PF11977.8 CDJ66002.1 - 3.5e-20 72.4 2.6 4.3e-20 72.1 0.0 2.3 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain N6_N4_Mtase PF01555.18 CDJ66002.1 - 0.0084 15.8 0.1 0.0084 15.8 0.1 1.8 2 0 0 2 2 2 1 DNA methylase DCX PF03607.17 CDJ66003.1 - 5.9e-09 35.9 0.0 1.5e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Doublecortin p25-alpha PF05517.12 CDJ66003.1 - 2.9e-08 34.0 0.0 4.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 p25-alpha Citrate_synt PF00285.21 CDJ66004.1 - 9.7e-93 311.1 0.8 5.9e-92 308.5 0.0 1.9 2 0 0 2 2 2 1 Citrate synthase, C-terminal domain DUF3883 PF13020.6 CDJ66007.1 - 1.4e-19 70.0 0.0 2.7e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Cupin_8 PF13621.6 CDJ66008.1 - 0.00046 20.0 0.0 0.00079 19.2 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain zf-HC2 PF13490.6 CDJ66008.1 - 0.0092 16.2 0.2 0.0092 16.2 0.2 2.0 2 0 0 2 2 2 1 Putative zinc-finger Cupin_8 PF13621.6 CDJ66009.1 - 4.3e-28 98.7 0.0 8.4e-28 97.8 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CDJ66009.1 - 0.00013 21.5 0.2 0.056 12.9 0.0 3.1 3 0 0 3 3 3 1 Cupin superfamily protein TRADD_N PF09034.10 CDJ66009.1 - 0.14 12.2 0.7 0.32 11.1 0.7 1.5 1 0 0 1 1 1 0 TRADD, N-terminal domain Seryl_tRNA_N PF02403.22 CDJ66009.1 - 0.15 12.3 1.5 0.26 11.6 1.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HSCB_C PF07743.13 CDJ66009.1 - 2.5 8.6 6.2 5.3 7.6 1.5 1.8 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Rieske PF00355.26 CDJ66010.1 - 3.9e-11 42.8 0.1 7.3e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 CDJ66010.1 - 0.034 14.6 0.1 0.11 13.0 0.1 1.9 1 1 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region EXS PF03124.14 CDJ66016.1 - 5.2e-67 226.5 11.2 7.5e-67 226.0 11.2 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CDJ66016.1 - 9.7e-18 65.2 11.0 9.4e-17 62.0 11.0 2.2 1 1 0 1 1 1 1 SPX domain FAM199X PF15814.5 CDJ66016.1 - 0.046 12.8 0.7 0.072 12.1 0.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X Stevor PF17410.2 CDJ66017.1 - 7.1 6.1 8.2 8.9 5.8 8.2 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Fringe PF02434.16 CDJ66018.1 - 2.4e-17 63.2 0.0 5.2e-07 29.3 0.0 3.4 3 0 0 3 3 3 3 Fringe-like DUF2828 PF11443.8 CDJ66019.1 - 3 5.8 17.6 0.94 7.5 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF1980 PF09323.10 CDJ66019.1 - 5.6 6.8 10.9 3.1 7.7 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) CLN3 PF02487.17 CDJ66019.1 - 5.9 5.8 12.0 7.4 5.5 1.8 2.4 2 0 0 2 2 2 0 CLN3 protein EIIBC-GUT_N PF03612.14 CDJ66019.1 - 8.1 6.1 16.9 0.23 11.2 1.5 3.3 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus MAM33 PF02330.16 CDJ66020.1 - 0.0012 18.9 5.7 0.56 10.1 2.2 3.2 3 0 0 3 3 3 2 Mitochondrial glycoprotein IMUP PF15761.5 CDJ66020.1 - 0.32 11.7 5.8 1.2 9.9 5.8 2.0 1 0 0 1 1 1 0 Immortalisation up-regulated protein Enkurin PF13864.6 CDJ66020.1 - 0.58 10.6 16.3 0.68 10.4 2.4 3.5 3 0 0 3 3 3 0 Calmodulin-binding DUF2722 PF10846.8 CDJ66021.1 - 2.7 6.8 16.1 0.9 8.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) E_Pc_C PF06752.12 CDJ66022.1 - 0.0067 16.6 10.4 0.015 15.5 10.4 1.6 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus Rotamase_2 PF13145.6 CDJ66022.1 - 0.038 14.8 6.3 0.088 13.7 0.1 2.9 2 0 0 2 2 2 0 PPIC-type PPIASE domain Rhomboid_N PF12122.8 CDJ66022.1 - 0.048 13.8 1.5 0.1 12.8 1.5 1.5 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease NAM-associated PF14303.6 CDJ66022.1 - 3.7 8.2 12.9 0.38 11.5 7.0 2.0 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain TPPII_N PF12583.8 CDJ66022.1 - 5.5 7.6 11.3 16 6.1 11.3 1.7 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Adaptin_binding PF10199.9 CDJ66023.1 - 9.7e-09 35.9 4.3 9.7e-09 35.9 4.3 3.1 2 2 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DUF2722 PF10846.8 CDJ66023.1 - 2.6e-06 26.7 10.1 2.6e-06 26.7 10.1 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ66023.1 - 0.00082 19.0 12.9 0.00082 19.0 12.9 5.0 2 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein CTNNB1_binding PF08347.11 CDJ66023.1 - 0.0077 16.4 1.4 0.0077 16.4 1.4 2.8 3 0 0 3 3 3 1 N-terminal CTNNB1 binding Utp14 PF04615.13 CDJ66023.1 - 0.18 10.4 27.2 0.31 9.5 27.2 1.3 1 1 0 1 1 1 0 Utp14 protein EOS1 PF12326.8 CDJ66023.1 - 0.32 10.9 12.2 0.062 13.2 2.0 2.4 2 0 0 2 2 2 0 N-glycosylation protein DUF572 PF04502.13 CDJ66023.1 - 0.39 10.3 25.1 0.23 11.0 9.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4045 PF13254.6 CDJ66023.1 - 2.2 7.8 32.2 0.81 9.3 11.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) FAM91_C PF14648.6 CDJ66023.1 - 3.9 6.2 12.6 1.5 7.6 6.4 2.1 2 0 0 2 2 2 0 FAM91 C-terminus RR_TM4-6 PF06459.12 CDJ66023.1 - 5.9 6.6 32.7 1.8 8.3 8.7 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Amido_AtzD_TrzD PF09663.10 CDJ66024.1 - 0.3 10.1 6.2 0.35 9.8 6.2 1.2 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) YppG PF14179.6 CDJ66025.1 - 0.029 15.1 0.4 0.029 15.1 0.4 4.2 3 2 0 3 3 3 0 YppG-like protein Pep_M12B_propep PF01562.19 CDJ66025.1 - 0.16 12.2 0.8 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Reprolysin family propeptide eIF-3_zeta PF05091.12 CDJ66025.1 - 9.4 5.1 10.8 16 4.3 10.8 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) OmpH PF03938.14 CDJ66026.1 - 0.038 14.3 3.4 0.038 14.3 3.4 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Caldesmon PF02029.15 CDJ66026.1 - 0.072 11.8 18.8 0.0043 15.9 10.1 2.0 2 0 0 2 2 2 0 Caldesmon DUF4148 PF13663.6 CDJ66026.1 - 0.12 12.5 20.9 0.4 10.9 1.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Misat_Tub_SegII PF10644.9 CDJ66026.1 - 0.83 10.0 4.0 0.78 10.1 2.0 2.1 1 1 1 2 2 2 0 Misato Segment II tubulin-like domain Myc_N PF01056.18 CDJ66026.1 - 4 7.2 24.9 0.16 11.8 12.7 2.3 1 1 2 3 3 3 0 Myc amino-terminal region PHD_3 PF13922.6 CDJ66026.1 - 4.9 7.6 6.1 19 5.7 1.9 2.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx XAP5 PF04921.14 CDJ66027.1 - 0.064 13.1 2.4 0.086 12.7 2.4 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Menin PF05053.13 CDJ66027.1 - 0.11 10.8 8.5 0.14 10.5 8.5 1.3 1 0 0 1 1 1 0 Menin NPR3 PF03666.13 CDJ66027.1 - 0.16 10.8 11.0 0.2 10.4 11.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SPX PF03105.19 CDJ66027.1 - 0.23 11.3 28.7 0.29 11.0 28.7 1.3 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 CDJ66027.1 - 0.32 9.7 10.3 0.44 9.3 10.3 1.3 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 CDJ66027.1 - 0.44 8.7 8.2 0.47 8.6 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family Tmemb_cc2 PF10267.9 CDJ66027.1 - 0.71 9.0 14.0 0.89 8.6 14.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Raftlin PF15250.6 CDJ66027.1 - 1.3 7.6 7.8 1.5 7.5 7.8 1.1 1 0 0 1 1 1 0 Raftlin SpoIIIAH PF12685.7 CDJ66027.1 - 1.6 8.5 20.5 2.4 7.9 20.3 1.3 1 1 0 1 1 1 0 SpoIIIAH-like protein FAM76 PF16046.5 CDJ66027.1 - 1.8 7.8 9.5 2.4 7.4 9.5 1.2 1 0 0 1 1 1 0 FAM76 protein CAML PF14963.6 CDJ66027.1 - 2.7 8.0 13.1 3.7 7.6 13.1 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Hid1 PF12722.7 CDJ66027.1 - 4.4 5.3 15.4 5.1 5.1 15.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RskA PF10099.9 CDJ66028.1 - 0.0013 19.1 34.1 0.92 9.8 18.8 3.4 1 1 1 2 2 2 2 Anti-sigma-K factor rskA Upf2 PF04050.14 CDJ66028.1 - 0.0014 19.4 1.1 0.0014 19.4 1.1 3.5 4 1 0 4 4 4 1 Up-frameshift suppressor 2 SPX PF03105.19 CDJ66028.1 - 0.11 12.4 22.8 0.22 11.4 13.4 2.3 2 0 0 2 2 2 0 SPX domain TFIIA PF03153.13 CDJ66028.1 - 6.2 6.7 16.7 20 5.1 16.7 1.8 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AMPK1_CBM PF16561.5 CDJ66029.1 - 5e-12 45.9 0.0 1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase MAT1 PF06391.13 CDJ66029.1 - 0.002 18.0 9.9 0.002 18.0 9.9 1.9 2 0 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 SAPS PF04499.15 CDJ66029.1 - 0.44 9.3 6.9 0.65 8.7 6.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIP PF07454.11 CDJ66029.1 - 0.64 9.4 10.5 1.1 8.7 10.5 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TRAP_alpha PF03896.16 CDJ66029.1 - 1.3 8.2 5.5 2.1 7.4 5.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4820 PF16091.5 CDJ66029.1 - 2 7.7 9.5 4.8 6.5 9.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Zip PF02535.22 CDJ66029.1 - 2.2 7.4 7.7 3.5 6.7 7.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ALMT PF11744.8 CDJ66029.1 - 2.8 6.7 8.0 4.5 6.0 8.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ66029.1 - 4.5 6.2 11.1 7.4 5.5 11.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF2828 PF11443.8 CDJ66029.1 - 6.4 4.7 13.6 10 4.1 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Endomucin PF07010.12 CDJ66029.1 - 7.4 6.5 15.6 20 5.1 15.6 1.7 1 0 0 1 1 1 0 Endomucin Ureide_permease PF07168.11 CDJ66029.1 - 7.7 5.2 5.3 14 4.3 5.3 1.3 1 0 0 1 1 1 0 Ureide permease FAM176 PF14851.6 CDJ66029.1 - 7.8 6.2 8.3 18 5.0 8.3 1.6 1 0 0 1 1 1 0 FAM176 family SR-25 PF10500.9 CDJ66030.1 - 2.4e-05 24.1 24.1 0.00011 21.8 3.9 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ66030.1 - 0.0043 17.3 3.8 0.0043 17.3 3.8 5.2 3 2 1 4 4 3 1 Early growth response N-terminal domain TPR_2 PF07719.17 CDJ66030.1 - 0.047 13.8 0.6 0.047 13.8 0.6 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat AF-4 PF05110.13 CDJ66030.1 - 0.14 10.2 34.6 0.49 8.4 19.6 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Lin-8 PF03353.15 CDJ66030.1 - 0.15 11.6 26.2 2.3 7.7 21.6 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SpoIIP PF07454.11 CDJ66030.1 - 0.3 10.5 16.1 0.39 10.1 14.4 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ66030.1 - 0.64 8.9 18.5 1.1 8.2 18.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDRGK PF09756.9 CDJ66030.1 - 0.75 9.4 22.3 1.3 8.6 22.3 1.3 1 0 0 1 1 1 0 DDRGK domain GEMIN8 PF15348.6 CDJ66030.1 - 2.6 8.3 26.4 4 7.7 18.6 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 CCSAP PF15748.5 CDJ66030.1 - 6 7.0 37.9 1.7 8.8 21.2 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated PNISR PF15996.5 CDJ66030.1 - 6.3 7.0 31.8 0.84 9.9 20.0 2.7 2 1 0 2 2 2 0 Arginine/serine-rich protein PNISR RskA PF10099.9 CDJ66031.1 - 0.062 13.6 53.8 0.028 14.7 11.0 3.2 1 1 2 3 3 3 0 Anti-sigma-K factor rskA DUF4551 PF15087.6 CDJ66031.1 - 0.29 9.9 18.1 0.38 9.5 18.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ATP_bind_1 PF03029.17 CDJ66033.1 - 1.2e-28 100.6 0.0 7.7e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein NUDIX_2 PF13869.6 CDJ66033.1 - 0.082 12.5 0.0 7.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Nucleotide hydrolase Macoilin PF09726.9 CDJ66033.1 - 0.18 10.3 13.2 0.024 13.2 7.7 1.9 2 0 0 2 2 2 0 Macoilin family Phage_min_cap2 PF06152.11 CDJ66033.1 - 0.26 10.1 2.7 0.36 9.7 2.7 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 Apt1 PF10351.9 CDJ66033.1 - 1.7 7.4 19.0 0.33 9.8 11.6 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ66034.1 - 4.4e-06 26.5 30.9 4.4e-06 26.5 30.9 7.8 8 2 1 9 9 9 2 Nuclear RNA-splicing-associated protein KCNQ2_u3 PF16642.5 CDJ66034.1 - 0.023 15.7 1.9 0.023 15.7 1.9 9.3 8 1 0 8 8 8 0 Unstructured region on Potassium channel subunit alpha KvLQT2 ACDC PF14733.6 CDJ66035.1 - 1.8e-06 28.1 0.0 4.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ66035.1 - 1.9e-05 24.8 1.5 1.9e-05 24.8 1.5 2.9 3 0 0 3 3 1 1 AP2 domain RIFIN PF02009.16 CDJ66035.1 - 0.012 15.6 6.7 0.016 15.1 6.7 1.3 1 0 0 1 1 1 0 Rifin DUF4834 PF16118.5 CDJ66035.1 - 0.026 15.5 0.6 0.056 14.4 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ66035.1 - 0.034 12.1 8.9 0.051 11.5 8.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.17 CDJ66035.1 - 0.086 13.0 3.1 0.12 12.5 3.1 1.4 1 0 0 1 1 1 0 DDHD domain Ins_P5_2-kin PF06090.12 CDJ66035.1 - 0.094 12.1 1.9 0.11 11.9 1.9 1.2 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase LpxB PF02684.15 CDJ66035.1 - 0.097 11.5 5.2 16 4.2 0.0 2.6 2 1 0 2 2 2 0 Lipid-A-disaccharide synthetase DUF1822 PF08852.11 CDJ66035.1 - 0.21 10.6 16.1 0.48 9.4 16.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) ALMT PF11744.8 CDJ66035.1 - 0.23 10.2 6.2 0.35 9.7 6.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter MDMPI_N PF11716.8 CDJ66035.1 - 0.39 11.4 26.9 0.12 13.0 16.2 3.0 3 0 0 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain TFB6 PF17110.5 CDJ66035.1 - 0.53 10.0 3.8 3.2 7.5 1.1 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF5421 PF17458.2 CDJ66035.1 - 0.6 9.4 10.5 0.94 8.8 10.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Band_3_cyto PF07565.13 CDJ66035.1 - 0.75 9.5 9.5 1.2 8.8 9.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Roughex PF06020.11 CDJ66035.1 - 0.97 8.5 13.9 1.8 7.6 13.9 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 CDJ66035.1 - 1.3 7.8 6.0 1.7 7.3 6.0 1.2 1 0 0 1 1 1 0 Presenilin Thioredoxin_4 PF13462.6 CDJ66035.1 - 9.4 6.4 19.1 19 5.4 1.1 2.7 2 1 0 2 2 2 0 Thioredoxin Kei1 PF08552.11 CDJ66035.1 - 9.6 6.0 11.2 9.2 6.1 10.1 1.6 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF755 PF05501.11 CDJ66036.1 - 0.00013 22.3 0.3 0.00013 22.3 0.3 7.2 7 1 0 7 7 7 1 Domain of unknown function (DUF755) Rad50_zn_hook PF04423.14 CDJ66037.1 - 0.05 13.4 0.1 0.05 13.4 0.1 5.7 7 0 0 7 7 7 0 Rad50 zinc hook motif VPS9 PF02204.18 CDJ66037.1 - 0.075 13.3 6.5 0.21 11.8 0.4 4.0 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain ThiF PF00899.21 CDJ66039.1 - 1.9e-37 129.0 0.0 1.9e-16 60.2 0.1 4.8 3 3 1 4 4 4 4 ThiF family Spt20 PF12090.8 CDJ66039.1 - 1.2e-06 28.3 28.8 0.0016 18.1 3.6 3.2 3 0 0 3 3 3 3 Spt20 family E1_4HB PF16191.5 CDJ66039.1 - 1.5e-06 28.3 1.7 6.2e-06 26.3 1.5 2.3 1 1 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle SR-25 PF10500.9 CDJ66039.1 - 8.4e-06 25.6 13.9 8.4e-06 25.6 13.9 2.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ66039.1 - 2.6e-05 23.4 21.0 0.002 17.2 4.2 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ66039.1 - 0.023 14.7 4.7 0.023 14.7 4.7 3.9 3 1 0 3 3 2 0 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 CDJ66039.1 - 0.024 15.0 9.2 0.39 11.1 0.1 3.5 4 0 0 4 4 3 0 Enhancer of polycomb-like DUF913 PF06025.12 CDJ66039.1 - 0.025 13.6 1.4 0.15 11.0 0.3 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) DUF4834 PF16118.5 CDJ66039.1 - 0.057 14.4 13.0 1.5 9.9 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Velvet PF11754.8 CDJ66039.1 - 0.082 12.8 12.9 0.2 11.6 12.6 1.8 1 1 0 1 1 1 0 Velvet factor SPX PF03105.19 CDJ66039.1 - 0.4 10.6 18.3 0.27 11.1 11.7 2.1 2 0 0 2 2 2 0 SPX domain FAM60A PF15396.6 CDJ66039.1 - 0.66 9.9 10.2 0.078 13.0 3.2 2.5 3 0 0 3 3 3 0 Protein Family FAM60A Bul1_C PF04426.12 CDJ66039.1 - 0.79 9.1 4.0 1.8 7.9 4.0 1.5 1 0 0 1 1 1 0 Bul1 C terminus TCP PF03634.13 CDJ66039.1 - 2.3 8.8 17.0 1.7 9.2 8.3 3.2 3 0 0 3 3 3 0 TCP family transcription factor CCDC106 PF15794.5 CDJ66039.1 - 3.7 7.2 15.7 0.079 12.7 6.2 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 V_ATPase_I PF01496.19 CDJ66039.1 - 6.9 4.4 8.4 0.28 9.0 1.1 2.0 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Peroxin-3 PF04882.12 CDJ66039.1 - 7.9 5.4 19.1 3.3 6.6 12.3 2.2 2 0 0 2 2 2 0 Peroxin-3 DAGK_cat PF00781.24 CDJ66040.1 - 4.3e-11 42.5 0.1 1.3e-08 34.5 0.1 2.7 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain SMN PF06003.12 CDJ66040.1 - 0.014 14.7 1.6 0.022 14.0 1.6 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ferlin_C PF16165.5 CDJ66040.1 - 0.3 11.0 2.5 0.67 9.9 2.5 1.5 1 0 0 1 1 1 0 Ferlin C-terminus Apt1 PF10351.9 CDJ66041.1 - 0.001 18.0 8.3 0.001 18.0 8.3 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain SPX PF03105.19 CDJ66041.1 - 0.026 14.5 9.5 0.03 14.3 9.5 1.2 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 CDJ66041.1 - 0.058 12.6 20.9 0.073 12.3 20.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Secretin_N_2 PF07655.13 CDJ66041.1 - 0.68 10.5 28.8 0.78 10.3 5.6 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain SOBP PF15279.6 CDJ66041.1 - 2.2 8.8 10.8 2.7 8.5 10.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Tic110 PF16940.5 CDJ66041.1 - 3.2 6.1 11.3 4.3 5.7 11.3 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter SRP-alpha_N PF04086.13 CDJ66041.1 - 7.3 6.4 10.6 10 5.9 10.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal V_ATPase_I PF01496.19 CDJ66042.1 - 4.7 5.0 7.7 6.7 4.5 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PUA_3 PF17785.1 CDJ66044.1 - 2.9e-12 46.2 0.0 6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain Apt1 PF10351.9 CDJ66044.1 - 0.0029 16.5 12.5 0.062 12.1 5.2 2.8 3 0 0 3 3 3 2 Golgi-body localisation protein domain DUF4148 PF13663.6 CDJ66044.1 - 8.6 6.6 23.1 2.2 8.5 7.0 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DJ-1_PfpI PF01965.24 CDJ66045.1 - 2.6e-05 24.1 0.0 2.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family RskA PF10099.9 CDJ66046.1 - 0.039 14.2 29.8 0.056 13.7 29.8 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ66046.1 - 4.4 7.9 6.8 9.2 6.8 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) TFIIA PF03153.13 CDJ66046.1 - 4.4 7.2 35.7 5.7 6.8 35.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ66047.1 - 0.32 11.3 9.3 0.37 11.0 9.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA YbgS PF13985.6 CDJ66047.1 - 2.2 8.6 13.2 2.5 8.4 13.2 1.0 1 0 0 1 1 1 0 YbgS-like protein DUF5349 PF17298.2 CDJ66048.1 - 0.21 11.3 11.1 0.24 11.1 11.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF755 PF05501.11 CDJ66048.1 - 1 9.6 19.7 2.2 8.6 19.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ66048.1 - 1.7 8.2 28.3 0.9 9.1 23.4 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF966 PF06136.13 CDJ66048.1 - 2.9 7.5 12.6 3.5 7.3 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TFIIF_alpha PF05793.12 CDJ66048.1 - 4.2 5.8 11.4 4.8 5.7 11.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2992 PF11208.8 CDJ66048.1 - 7.4 6.8 7.6 4.2 7.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) GREB1 PF15782.5 CDJ66048.1 - 7.9 3.4 7.4 8.5 3.4 7.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer COPI_assoc PF08507.10 CDJ66050.1 - 0.004 17.2 4.2 0.0081 16.2 4.2 1.4 1 0 0 1 1 1 1 COPI associated protein Apq12 PF12716.7 CDJ66050.1 - 7 6.7 9.1 0.36 10.8 0.6 2.7 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis Spt20 PF12090.8 CDJ66051.1 - 0.0018 17.9 17.2 0.0028 17.3 17.2 1.4 1 0 0 1 1 1 1 Spt20 family DUF3464 PF11947.8 CDJ66051.1 - 0.0082 15.9 1.7 0.012 15.4 1.7 1.3 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 DUF2722 PF10846.8 CDJ66051.1 - 0.0099 14.9 12.9 0.013 14.5 12.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TERB2 PF15101.6 CDJ66051.1 - 0.012 15.7 7.9 0.02 14.9 7.9 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RAP PF08373.10 CDJ66051.1 - 0.026 14.6 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 RAP domain DDHD PF02862.17 CDJ66051.1 - 0.027 14.7 1.3 0.03 14.5 1.3 1.3 1 0 0 1 1 1 0 DDHD domain MMR1 PF08505.10 CDJ66051.1 - 0.027 14.8 5.8 0.039 14.3 5.8 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TMEM51 PF15345.6 CDJ66051.1 - 0.071 12.9 4.1 0.1 12.4 4.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Rxt3 PF08642.10 CDJ66051.1 - 0.087 13.6 2.1 0.16 12.7 2.1 1.5 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 CCDC53 PF10152.9 CDJ66051.1 - 0.09 13.2 8.8 0.017 15.5 4.6 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 CDJ66051.1 - 0.27 9.9 5.8 0.34 9.6 5.8 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ66051.1 - 0.35 8.8 4.2 0.41 8.5 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 CDJ66051.1 - 0.49 10.4 2.9 0.59 10.2 2.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 CDJ66051.1 - 0.73 9.5 2.8 1 9.1 2.8 1.2 1 0 0 1 1 1 0 Connexin Pex14_N PF04695.13 CDJ66051.1 - 1.6 9.4 17.4 2.5 8.7 16.8 1.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 CDJ66051.1 - 2.6 9.1 6.7 5 8.2 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EIIBC-GUT_N PF03612.14 CDJ66051.1 - 6.5 6.5 7.0 10 5.8 7.0 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus BRCT_assoc PF12820.7 CDJ66051.1 - 6.7 6.5 8.2 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Serine-rich domain associated with BRCT NiFe-hyd_HybE PF11939.8 CDJ66051.1 - 7.3 6.5 12.2 12 5.7 3.5 2.5 1 1 1 2 2 2 0 [NiFe]-hydrogenase assembly, chaperone, HybE ESM4 PF15952.5 CDJ66051.1 - 8.2 6.8 20.8 0.92 9.9 14.1 2.2 1 1 1 2 2 2 0 Enhancer of split M4 family Androgen_recep PF02166.16 CDJ66051.1 - 9.2 5.0 36.0 0.5 9.2 24.0 2.4 2 0 0 2 2 2 0 Androgen receptor CPSF100_C PF13299.6 CDJ66051.1 - 9.8 6.3 11.3 11 6.2 10.0 1.7 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ribosomal_60s PF00428.19 CDJ66053.1 - 0.013 16.1 10.6 0.013 16.1 10.6 3.8 2 1 0 2 2 2 0 60s Acidic ribosomal protein PQ-loop PF04193.14 CDJ66053.1 - 0.027 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 PQ loop repeat SseC PF04888.12 CDJ66053.1 - 7.7 6.0 32.7 9.6 5.7 32.7 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family S1 PF00575.23 CDJ66054.1 - 1.8e-12 47.4 0.2 2.3e-12 47.1 0.2 1.1 1 0 0 1 1 1 1 S1 RNA binding domain EcKinase PF02958.20 CDJ66054.1 - 0.0059 16.0 0.2 0.0068 15.7 0.2 1.0 1 0 0 1 1 1 1 Ecdysteroid kinase EXOSC1 PF10447.9 CDJ66054.1 - 0.1 13.2 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 RNA_pol_Rpb1_2 PF00623.20 CDJ66056.1 - 2.5e-64 216.5 0.0 3.6e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 CDJ66056.1 - 1e-37 130.2 0.0 1.4e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 CDJ66056.1 - 1.9e-18 66.9 0.0 3.1e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 Ribosomal_60s PF00428.19 CDJ66056.1 - 0.044 14.4 9.5 0.095 13.3 9.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3138 PF11336.8 CDJ66056.1 - 0.29 9.7 3.1 0.43 9.1 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ASFV_J13L PF05568.11 CDJ66056.1 - 0.5 10.1 1.6 0.89 9.3 1.6 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Fasciclin PF02469.22 CDJ66057.1 - 4.1e-11 43.2 0.0 7.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain IMUP PF15761.5 CDJ66057.1 - 8.1e-05 23.3 24.3 0.0083 16.8 2.9 2.6 2 0 0 2 2 2 2 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ66057.1 - 0.0001 22.0 30.8 0.0033 17.1 13.9 3.0 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Herpes_capsid PF06112.11 CDJ66057.1 - 3.6 7.6 20.8 0.84 9.7 10.0 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Spt20 PF12090.8 CDJ66057.1 - 3.8 7.1 19.8 1.3 8.5 12.8 2.6 2 1 1 3 3 3 0 Spt20 family DUF3446 PF11928.8 CDJ66057.1 - 9.2 6.7 31.3 1.8 9.0 4.6 2.8 3 0 0 3 3 3 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ66058.1 - 8.2e-08 32.1 24.4 1.2e-07 31.6 24.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ66058.1 - 0.0007 19.9 11.9 0.0012 19.2 11.9 1.4 1 1 0 1 1 1 1 Anti-sigma-K factor rskA DUF4207 PF13904.6 CDJ66058.1 - 0.001 18.8 15.4 0.0012 18.6 15.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) Ribosomal_60s PF00428.19 CDJ66058.1 - 0.002 18.7 10.1 0.0032 18.0 10.1 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein Med3 PF11593.8 CDJ66058.1 - 0.003 16.8 23.7 0.0037 16.5 23.7 1.0 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Cwf_Cwc_15 PF04889.12 CDJ66058.1 - 0.0049 16.6 3.5 0.0065 16.2 3.5 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 CDJ66058.1 - 0.0052 16.8 19.7 0.006 16.6 19.7 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ66058.1 - 0.0073 15.3 4.9 0.0076 15.3 4.9 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SprA-related PF12118.8 CDJ66058.1 - 0.0079 15.4 25.2 0.0096 15.1 25.2 1.0 1 0 0 1 1 1 1 SprA-related family Nop53 PF07767.11 CDJ66058.1 - 0.032 13.6 13.7 0.041 13.3 13.7 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FAM199X PF15814.5 CDJ66058.1 - 0.038 13.1 24.4 0.047 12.8 24.4 1.0 1 0 0 1 1 1 0 Protein family FAM199X TCP PF03634.13 CDJ66058.1 - 0.055 14.0 14.2 0.073 13.6 14.2 1.1 1 0 0 1 1 1 0 TCP family transcription factor OMP_b-brl PF13505.6 CDJ66058.1 - 0.068 13.3 4.0 0.084 13.0 4.0 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain DUF4614 PF15391.6 CDJ66058.1 - 0.095 12.7 13.6 0.14 12.2 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Velvet PF11754.8 CDJ66058.1 - 0.1 12.5 9.8 0.11 12.4 9.8 1.1 1 0 0 1 1 1 0 Velvet factor SOBP PF15279.6 CDJ66058.1 - 0.11 13.1 10.2 0.12 12.9 10.2 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein NAM-associated PF14303.6 CDJ66058.1 - 0.15 12.8 13.4 0.22 12.3 13.4 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PAF PF15715.5 CDJ66058.1 - 0.18 12.4 15.3 0.3 11.7 15.3 1.4 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Presenilin PF01080.17 CDJ66058.1 - 0.27 9.9 14.3 0.34 9.6 14.3 1.0 1 0 0 1 1 1 0 Presenilin SMYLE_N PF18615.1 CDJ66058.1 - 0.28 10.7 13.1 0.35 10.4 13.1 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain IHABP4_N PF16174.5 CDJ66058.1 - 0.49 11.0 17.7 0.69 10.5 17.7 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Suf PF05843.14 CDJ66058.1 - 0.5 10.3 11.8 0.58 10.1 11.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF572 PF04502.13 CDJ66058.1 - 0.59 9.7 9.8 0.72 9.4 9.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC45 PF02724.14 CDJ66058.1 - 0.66 8.2 9.9 0.78 8.0 9.9 1.0 1 0 0 1 1 1 0 CDC45-like protein TPPII_N PF12583.8 CDJ66058.1 - 0.98 10.0 18.1 1.3 9.6 18.1 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal XK-related PF09815.9 CDJ66058.1 - 1.2 8.1 9.1 1.8 7.5 9.1 1.3 1 0 0 1 1 1 0 XK-related protein BAF1_ABF1 PF04684.13 CDJ66058.1 - 1.6 7.7 9.9 2.3 7.2 9.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Bul1_C PF04426.12 CDJ66058.1 - 2.3 7.5 7.8 3.1 7.1 7.8 1.1 1 0 0 1 1 1 0 Bul1 C terminus Ndc1_Nup PF09531.10 CDJ66058.1 - 4.8 5.7 14.7 5.3 5.6 14.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 CDJ66058.1 - 5.2 7.0 6.3 6.6 6.7 6.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.12 CDJ66058.1 - 9.5 5.5 12.8 12 5.1 12.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Dehydrin PF00257.19 CDJ66060.1 - 0.0013 19.3 8.1 0.048 14.2 0.4 2.1 2 0 0 2 2 2 2 Dehydrin Ribosomal_60s PF00428.19 CDJ66060.1 - 0.016 15.8 0.8 0.016 15.8 0.8 1.9 2 1 0 2 2 2 0 60s Acidic ribosomal protein DUF4692 PF15763.5 CDJ66060.1 - 0.034 14.6 0.1 0.062 13.8 0.1 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) V_ATPase_I PF01496.19 CDJ66061.1 - 5 4.9 15.8 7.3 4.4 15.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PHD PF00628.29 CDJ66062.1 - 1.1e-07 31.6 4.0 4.1e-07 29.8 4.0 2.0 1 0 0 1 1 1 1 PHD-finger Macoilin PF09726.9 CDJ66062.1 - 0.0031 16.2 7.0 0.0031 16.2 7.0 3.3 3 0 0 3 3 3 2 Macoilin family DUF755 PF05501.11 CDJ66062.1 - 0.014 15.7 17.5 0.014 15.7 17.5 5.2 5 0 0 5 5 5 0 Domain of unknown function (DUF755) DUF4451 PF14616.6 CDJ66062.1 - 1.7 8.8 4.9 8.2 6.6 4.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) Peptidase_S66C PF17676.1 CDJ66065.1 - 0.075 13.6 0.0 0.079 13.5 0.0 1.0 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain Spt20 PF12090.8 CDJ66066.1 - 0.0037 16.9 25.0 0.0037 16.9 25.0 3.2 2 1 1 3 3 3 1 Spt20 family RskA PF10099.9 CDJ66066.1 - 0.014 15.7 14.4 0.014 15.7 14.4 4.2 1 1 1 3 3 3 0 Anti-sigma-K factor rskA Herpes_LMP2 PF07415.11 CDJ66066.1 - 3.6 6.3 6.8 6.1 5.5 6.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein TFIIA PF03153.13 CDJ66067.1 - 0.0043 17.1 33.4 0.0048 17.0 33.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ66067.1 - 0.025 13.4 14.5 0.026 13.3 14.5 1.0 1 0 0 1 1 1 0 Presenilin CNDH2_C PF16858.5 CDJ66067.1 - 0.03 14.2 11.3 0.033 14.1 11.3 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term MDM10 PF12519.8 CDJ66067.1 - 0.046 12.6 6.7 0.05 12.5 6.7 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Activator_LAG-3 PF11498.8 CDJ66067.1 - 0.074 12.0 45.9 0.087 11.8 45.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Band_3_cyto PF07565.13 CDJ66067.1 - 0.093 12.5 8.2 0.1 12.3 8.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SLC12 PF03522.15 CDJ66067.1 - 0.13 11.3 10.5 0.14 11.2 10.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 BAF1_ABF1 PF04684.13 CDJ66067.1 - 0.2 10.6 14.1 0.24 10.4 14.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MMR1 PF08505.10 CDJ66067.1 - 0.22 11.8 13.3 0.27 11.5 13.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Neur_chan_memb PF02932.16 CDJ66067.1 - 0.22 11.5 9.9 0.26 11.3 9.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.9 CDJ66067.1 - 0.23 11.5 7.8 0.3 11.1 7.8 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family OATP PF03137.20 CDJ66067.1 - 0.31 9.3 2.9 0.33 9.2 2.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ALMT PF11744.8 CDJ66067.1 - 0.37 9.6 6.6 0.42 9.4 6.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Otopetrin PF03189.13 CDJ66067.1 - 0.45 9.3 3.1 0.46 9.3 3.1 1.1 1 0 0 1 1 1 0 Otopetrin RIFIN PF02009.16 CDJ66067.1 - 0.47 10.3 11.6 0.67 9.8 11.6 1.2 1 0 0 1 1 1 0 Rifin Connexin PF00029.19 CDJ66067.1 - 0.53 10.0 8.0 0.53 10.0 8.0 1.3 1 0 0 1 1 1 0 Connexin DUF913 PF06025.12 CDJ66067.1 - 0.62 9.0 8.5 0.74 8.7 8.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PAT1 PF09770.9 CDJ66067.1 - 0.71 8.1 21.9 0.72 8.0 21.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 CDJ66067.1 - 0.86 9.1 16.2 1 8.9 16.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist V_ATPase_I PF01496.19 CDJ66067.1 - 1.2 7.0 12.2 1.3 6.9 12.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF908 PF06012.12 CDJ66067.1 - 1.2 8.4 9.3 1.5 8.2 9.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Totivirus_coat PF05518.11 CDJ66067.1 - 1.3 7.0 19.5 1.6 6.7 19.5 1.0 1 0 0 1 1 1 0 Totivirus coat protein Plasmodium_Vir PF05795.11 CDJ66067.1 - 1.4 8.3 6.9 1.5 8.1 6.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MCM_bind PF09739.9 CDJ66067.1 - 1.4 7.2 12.3 1.5 7.2 12.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NST1 PF13945.6 CDJ66067.1 - 1.6 8.8 20.7 2.3 8.3 20.7 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Pannexin_like PF12534.8 CDJ66067.1 - 1.6 7.7 7.0 1.7 7.7 7.0 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 PIP5K PF01504.18 CDJ66067.1 - 1.6 7.8 9.3 1.7 7.8 9.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF4638 PF15472.6 CDJ66067.1 - 1.7 8.3 11.7 1.8 8.2 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) CLN3 PF02487.17 CDJ66067.1 - 1.8 7.5 7.8 2 7.4 7.8 1.2 1 0 0 1 1 1 0 CLN3 protein GREB1 PF15782.5 CDJ66067.1 - 1.9 5.5 12.1 2.1 5.4 12.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF-3_zeta PF05091.12 CDJ66067.1 - 2.7 6.9 21.0 2.9 6.7 21.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM176 PF14851.6 CDJ66067.1 - 2.7 7.6 8.9 3.9 7.1 8.9 1.4 1 0 0 1 1 1 0 FAM176 family Ndc1_Nup PF09531.10 CDJ66067.1 - 3.2 6.3 13.3 3.5 6.2 13.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF966 PF06136.13 CDJ66067.1 - 3.3 7.3 11.6 3.7 7.2 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF2052 PF09747.9 CDJ66067.1 - 3.4 7.8 18.4 4.4 7.4 18.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Peptidase_S64 PF08192.11 CDJ66067.1 - 4.2 5.8 9.6 4.4 5.7 9.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 CDC45 PF02724.14 CDJ66067.1 - 4.2 5.6 12.2 4.6 5.4 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1980 PF09323.10 CDJ66067.1 - 4.2 7.3 8.0 4.6 7.1 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Med15 PF09606.10 CDJ66067.1 - 5.1 5.6 45.8 5.6 5.5 45.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.12 CDJ66067.1 - 5.2 6.8 17.0 6.9 6.4 17.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 API5 PF05918.11 CDJ66067.1 - 5.4 5.7 15.2 6.1 5.5 15.2 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) UPF0560 PF10577.9 CDJ66067.1 - 7.1 5.0 22.4 7.9 4.8 22.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2828 PF11443.8 CDJ66067.1 - 7.5 4.5 14.7 8.8 4.3 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) BAT2_N PF07001.11 CDJ66067.1 - 8 6.9 25.8 13 6.2 25.8 1.3 1 0 0 1 1 1 0 BAT2 N-terminus EMC3_TMCO1 PF01956.16 CDJ66067.1 - 8.8 6.0 10.5 10 5.8 10.5 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF5427 PF10310.9 CDJ66067.1 - 9.1 5.1 25.7 11 4.9 25.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) HGTP_anticodon2 PF12745.7 CDJ66067.1 - 9.3 5.7 16.5 13 5.2 16.5 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Na_H_Exchanger PF00999.21 CDJ66068.1 - 2.3e-13 49.7 6.8 2e-09 36.7 2.4 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family TFIIA PF03153.13 CDJ66068.1 - 3.7 7.4 20.3 5 7.0 20.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ACDC PF14733.6 CDJ66069.1 - 6.4e-14 52.0 0.8 6.4e-14 52.0 0.8 1.7 2 0 0 2 2 2 1 AP2-coincident C-terminal RskA PF10099.9 CDJ66071.1 - 9 6.5 30.6 20 5.4 30.6 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA LIN37 PF15306.6 CDJ66072.1 - 0.38 11.0 14.6 0.55 10.4 14.6 1.2 1 0 0 1 1 1 0 LIN37 Presenilin PF01080.17 CDJ66072.1 - 0.42 9.3 12.5 0.51 9.1 12.5 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ66072.1 - 0.45 10.5 37.9 0.64 10.0 37.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 CDJ66072.1 - 0.46 10.1 18.1 0.54 9.9 18.1 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SLC12 PF03522.15 CDJ66072.1 - 0.64 9.0 7.5 0.7 8.9 7.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PAT1 PF09770.9 CDJ66072.1 - 1.4 7.1 26.0 1.4 7.1 26.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 CDJ66072.1 - 1.7 8.2 13.4 2.2 7.8 13.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist YjbH PF06082.11 CDJ66072.1 - 3.4 6.4 9.1 3.9 6.2 9.1 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH SPX PF03105.19 CDJ66073.1 - 0.00038 20.5 23.7 0.00043 20.3 10.2 2.2 2 0 0 2 2 2 2 SPX domain Apt1 PF10351.9 CDJ66073.1 - 0.0065 15.4 26.2 0.015 14.2 14.6 2.1 2 0 0 2 2 2 2 Golgi-body localisation protein domain DDHD PF02862.17 CDJ66073.1 - 0.0069 16.6 8.2 0.18 11.9 1.2 2.2 2 0 0 2 2 2 2 DDHD domain DUF3173 PF11372.8 CDJ66073.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) DUF4228 PF14009.6 CDJ66073.1 - 0.067 13.6 16.5 0.18 12.2 4.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Macoilin PF09726.9 CDJ66073.1 - 0.093 11.3 28.1 0.099 11.2 16.8 2.2 2 0 0 2 2 2 0 Macoilin family Ctr PF04145.15 CDJ66073.1 - 0.19 12.3 6.9 1.6 9.3 0.2 2.5 2 0 0 2 2 2 0 Ctr copper transporter family FAM199X PF15814.5 CDJ66073.1 - 0.76 8.8 37.2 0.83 8.6 25.1 2.3 2 0 0 2 2 2 0 Protein family FAM199X Miga PF10265.9 CDJ66073.1 - 2.3 7.1 22.3 1.3 7.9 12.8 2.1 2 0 0 2 2 2 0 Mitoguardin Tmemb_cc2 PF10267.9 CDJ66073.1 - 2.4 7.2 13.6 0.095 11.8 4.1 2.1 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF4050 PF13259.6 CDJ66073.1 - 2.7 8.3 16.0 1.5 9.1 5.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Gti1_Pac2 PF09729.9 CDJ66073.1 - 3.1 7.9 16.0 3.7 7.6 5.4 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family QWRF PF04484.12 CDJ66073.1 - 3.5 7.3 29.7 4.4 7.0 16.6 2.2 2 0 0 2 2 2 0 QWRF family Sec3_C PF09763.9 CDJ66073.1 - 6.9 4.9 16.3 2.8 6.2 6.8 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec3 ANAPC1 PF12859.7 CDJ66073.1 - 8.4 7.0 24.4 23 5.5 0.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Presenilin PF01080.17 CDJ66073.1 - 8.8 5.0 15.2 1.6 7.4 3.8 2.1 2 0 0 2 2 2 0 Presenilin HEAT PF02985.22 CDJ66075.1 - 0.0047 17.1 4.7 0.92 9.9 0.1 3.2 3 0 0 3 3 3 2 HEAT repeat Adaptin_N PF01602.20 CDJ66075.1 - 0.016 13.8 0.3 0.02 13.5 0.3 1.1 1 0 0 1 1 1 0 Adaptin N terminal region zf-U1 PF06220.12 CDJ66076.1 - 1.7e-17 62.9 1.5 2.4e-17 62.4 1.5 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.7 CDJ66076.1 - 5.6 7.5 5.2 67 4.1 5.2 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ66076.1 - 6.3 7.2 5.7 0.63 10.4 1.3 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding SPX PF03105.19 CDJ66077.1 - 0.081 12.8 6.3 0.085 12.8 6.3 1.1 1 0 0 1 1 1 0 SPX domain DUF1891 PF09004.10 CDJ66077.1 - 0.23 11.1 1.1 0.42 10.2 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) Apt1 PF10351.9 CDJ66077.1 - 4.9 5.9 12.6 6.2 5.5 12.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ANAPC4_WD40 PF12894.7 CDJ66078.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain SOBP PF15279.6 CDJ66079.1 - 0.0003 21.5 20.0 0.00034 21.3 20.0 1.2 1 0 0 1 1 1 1 Sine oculis-binding protein DUF572 PF04502.13 CDJ66079.1 - 0.22 11.1 23.0 0.27 10.8 23.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) ALMT PF11744.8 CDJ66079.1 - 0.25 10.1 21.3 0.3 9.9 21.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Caldesmon PF02029.15 CDJ66079.1 - 0.26 10.0 30.5 0.32 9.7 30.5 1.1 1 0 0 1 1 1 0 Caldesmon RR_TM4-6 PF06459.12 CDJ66079.1 - 0.48 10.2 29.0 0.87 9.4 29.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 CDJ66079.1 - 0.52 8.5 41.4 0.65 8.2 41.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ66079.1 - 0.6 9.7 43.0 1.2 8.7 43.0 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ66079.1 - 0.64 8.0 34.6 0.83 7.7 34.6 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Hamartin PF04388.12 CDJ66079.1 - 0.71 8.5 22.4 0.71 8.5 22.4 1.1 1 0 0 1 1 1 0 Hamartin protein GREB1 PF15782.5 CDJ66079.1 - 1.5 5.8 28.2 1.7 5.7 28.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SID-1_RNA_chan PF13965.6 CDJ66079.1 - 1.6 7.0 10.6 2.1 6.7 10.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 CDJ66079.1 - 1.7 6.4 23.8 2.2 6.1 23.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2126 PF09899.9 CDJ66079.1 - 2.3 6.2 13.9 2.9 5.8 13.9 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SAPS PF04499.15 CDJ66079.1 - 3.3 6.4 17.7 3.9 6.1 17.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_S64 PF08192.11 CDJ66079.1 - 3.4 6.1 23.5 4 5.8 23.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Asp-B-Hydro_N PF05279.11 CDJ66079.1 - 3.6 7.6 17.8 5.4 7.0 17.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Zip PF02535.22 CDJ66079.1 - 4.2 6.5 17.1 6.4 5.9 17.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 CDJ66079.1 - 4.2 6.1 22.0 5.6 5.7 22.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Endostatin PF06482.11 CDJ66079.1 - 4.3 6.7 25.0 6.4 6.1 25.0 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CDK5_activator PF03261.15 CDJ66079.1 - 4.6 6.7 22.8 5.8 6.4 22.8 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Cellulose_synt PF03552.14 CDJ66079.1 - 6.4 5.1 7.4 7.1 5.0 7.4 1.1 1 0 0 1 1 1 0 Cellulose synthase SLC12 PF03522.15 CDJ66079.1 - 8 5.4 26.9 11 4.9 26.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF1387 PF07139.11 CDJ66079.1 - 8.6 6.0 28.8 12 5.5 28.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) KH_1 PF00013.29 CDJ66081.1 - 7.3e-42 141.0 0.8 2.2e-14 53.0 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CDJ66081.1 - 8.8e-12 44.7 4.1 0.00038 20.2 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CDJ66081.1 - 1.5e-05 24.8 0.1 1.3 8.9 0.0 3.6 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 CDJ66081.1 - 0.00037 20.5 1.7 5.6 7.1 0.1 3.4 3 0 0 3 3 3 0 NusA-like KH domain EphA2_TM PF14575.6 CDJ66081.1 - 0.0014 19.4 1.0 0.18 12.7 0.0 2.4 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Spt20 PF12090.8 CDJ66081.1 - 0.017 14.7 33.1 0.053 13.1 12.3 2.2 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ66081.1 - 0.02 14.9 31.8 0.25 11.3 16.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ctf8 PF09696.10 CDJ66081.1 - 0.022 15.1 9.9 0.061 13.7 1.9 2.4 2 0 0 2 2 2 0 Ctf8 RskA PF10099.9 CDJ66081.1 - 0.033 14.5 0.8 0.033 14.5 0.8 3.9 2 1 1 3 3 3 0 Anti-sigma-K factor rskA BCIP PF13862.6 CDJ66081.1 - 0.045 13.5 2.5 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 p21-C-terminal region-binding protein TMEM171 PF15471.6 CDJ66081.1 - 0.063 12.3 4.2 0.32 9.9 0.3 2.1 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF2052 PF09747.9 CDJ66081.1 - 0.077 13.1 9.6 0.35 11.0 3.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4366 PF14283.6 CDJ66081.1 - 0.12 12.4 4.2 0.31 11.1 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) INSIG PF07281.12 CDJ66081.1 - 0.16 11.6 1.8 0.69 9.5 0.3 2.1 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) DUF4834 PF16118.5 CDJ66081.1 - 0.3 12.1 11.4 2.5 9.1 2.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DDHD PF02862.17 CDJ66081.1 - 0.31 11.2 7.5 1 9.4 1.6 2.3 2 0 0 2 2 2 0 DDHD domain TERB2 PF15101.6 CDJ66081.1 - 0.32 11.0 12.5 0.35 10.9 3.3 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 MMR1 PF08505.10 CDJ66081.1 - 0.56 10.4 11.7 0.56 10.5 3.3 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein EPL1 PF10513.9 CDJ66081.1 - 0.93 9.9 11.0 0.97 9.8 2.5 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF3371 PF11851.8 CDJ66081.1 - 1.2 10.2 13.4 5.6 8.1 4.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) DUF4770 PF15994.5 CDJ66081.1 - 1.2 9.3 9.6 2.6 8.3 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Phostensin_N PF13916.6 CDJ66081.1 - 1.6 9.2 12.5 5.7 7.3 1.9 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal AAA_23 PF13476.6 CDJ66081.1 - 1.6 9.2 13.0 3.1 8.3 4.1 2.3 2 0 0 2 2 2 0 AAA domain RMP PF14996.6 CDJ66081.1 - 2.5 8.3 6.5 2.2 8.5 1.6 2.2 2 0 0 2 2 2 0 Retinal Maintenance IHABP4_N PF16174.5 CDJ66081.1 - 2.6 8.6 17.0 5.2 7.6 9.5 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Neur_chan_memb PF02932.16 CDJ66081.1 - 3.9 7.5 6.4 5 7.1 1.9 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF853 PF05872.12 CDJ66081.1 - 4 5.9 13.7 4 5.9 5.7 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) PRTP PF01366.18 CDJ66081.1 - 4.2 5.3 10.0 0.12 10.4 2.7 1.9 2 0 0 2 2 2 0 Herpesvirus processing and transport protein DUF2722 PF10846.8 CDJ66081.1 - 4.4 6.1 31.0 0.33 9.9 9.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ66081.1 - 4.4 7.2 12.3 4.5 7.2 3.6 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.6 CDJ66081.1 - 5 6.3 11.1 1.6 7.9 1.4 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus UPF0560 PF10577.9 CDJ66081.1 - 5.7 5.3 18.4 1.7 7.1 6.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 CNDH2_M PF16869.5 CDJ66081.1 - 6.1 7.5 7.6 23 5.7 1.2 2.4 2 0 0 2 2 2 0 PF16858 FAM150 PF15129.6 CDJ66081.1 - 6.8 6.9 11.4 2.4 8.3 2.0 2.4 2 0 0 2 2 2 0 FAM150 family Activator_LAG-3 PF11498.8 CDJ66081.1 - 7 5.5 44.9 0.36 9.7 16.6 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF775 PF05603.12 CDJ66081.1 - 8.4 5.9 18.3 1 8.8 6.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF775) LMBR1 PF04791.16 CDJ66081.1 - 9.8 4.9 5.6 1.2 7.9 1.3 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein Copine PF07002.16 CDJ66083.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Copine Tcf25 PF04910.14 CDJ66084.1 - 4.1e-45 154.4 3.1 6.2e-45 153.8 3.1 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PITH PF06201.13 CDJ66085.1 - 2.4e-22 79.8 0.0 6.3e-21 75.2 0.0 2.0 1 1 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 CDJ66086.1 - 8.9e-20 70.6 0.4 1e-19 70.4 0.4 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDJ66086.1 - 0.0041 17.4 0.0 0.0065 16.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like KaiB PF07689.12 CDJ66086.1 - 0.038 13.7 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 KaiB domain CS PF04969.16 CDJ66087.1 - 1.1e-05 26.3 0.0 2.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 CS domain CK_II_beta PF01214.18 CDJ66088.1 - 1.1e-61 207.8 0.0 2.8e-61 206.5 0.0 1.6 2 0 0 2 2 2 1 Casein kinase II regulatory subunit Radial_spoke PF04712.12 CDJ66088.1 - 0.11 11.4 4.2 0.15 11.0 4.2 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 CDJ66088.1 - 9 4.3 7.5 11 4.0 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi AAA_33 PF13671.6 CDJ66089.1 - 6.9e-27 94.4 0.0 1.4e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain SPRY PF00622.28 CDJ66089.1 - 1.5e-18 67.1 0.0 1.5e-18 67.1 0.0 2.7 2 1 1 3 3 3 1 SPRY domain AAA_18 PF13238.6 CDJ66089.1 - 0.059 13.9 0.1 0.29 11.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain Peptidase_M28 PF04389.17 CDJ66090.1 - 1.4e-23 83.6 0.0 3.7e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 SUIM_assoc PF16619.5 CDJ66090.1 - 0.12 12.5 5.6 0.036 14.1 1.0 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Metallophos PF00149.28 CDJ66091.1 - 3.8e-32 112.4 0.0 5.8e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CDJ66091.1 - 5.1e-17 62.0 0.0 1.2e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.17 CDJ66091.1 - 1.4e-13 49.8 5.8 0.00021 21.2 0.8 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ66091.1 - 4e-13 48.6 5.2 0.00012 21.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ66091.1 - 2.3e-06 27.2 0.5 0.0017 18.0 0.1 3.1 2 1 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 CDJ66091.1 - 1e-05 25.7 0.6 8.7e-05 22.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ66091.1 - 0.0025 18.4 3.4 0.21 12.3 0.7 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ66091.1 - 0.0042 17.8 3.3 8.8 7.4 0.0 4.4 3 2 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ66091.1 - 0.006 16.7 2.0 0.066 13.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ66091.1 - 0.03 14.7 0.9 0.58 10.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pex26 PF07163.12 CDJ66091.1 - 0.072 12.4 1.2 0.27 10.5 0.0 2.0 2 0 0 2 2 2 0 Pex26 protein TPR_9 PF13371.6 CDJ66091.1 - 0.072 13.2 0.3 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ66091.1 - 3.6 8.2 7.2 35 5.0 0.6 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat MIF PF01187.18 CDJ66092.1 - 1.9e-19 70.1 0.1 2e-19 70.0 0.1 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 CDJ66092.1 - 0.19 11.7 0.0 3.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme Sortilin-Vps10 PF15902.5 CDJ66093.1 - 1.3e-94 317.5 1.4 1.5e-45 155.8 0.0 3.1 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CDJ66093.1 - 8.4e-41 140.1 0.5 1.5e-40 139.4 0.5 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CDJ66093.1 - 3e-06 26.4 14.6 1.2 9.5 0.3 7.1 7 0 0 7 7 7 3 BNR/Asp-box repeat BNR_2 PF13088.6 CDJ66093.1 - 0.00016 21.1 0.0 1.1 8.4 0.0 3.6 3 1 0 3 3 3 2 BNR repeat-like domain BNR_6 PF15899.5 CDJ66093.1 - 0.26 11.4 0.9 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 BNR-Asp box repeat LAP1C PF05609.12 CDJ66095.1 - 1.4 7.9 19.8 1.7 7.7 19.8 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CCSAP PF15748.5 CDJ66095.1 - 3 8.0 18.9 3.4 7.8 18.9 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF2052 PF09747.9 CDJ66095.1 - 3.6 7.7 13.0 4.4 7.4 13.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Anp1 PF03452.14 CDJ66095.1 - 4.6 6.6 10.7 5.3 6.4 10.7 1.2 1 0 0 1 1 1 0 Anp1 TFIIA PF03153.13 CDJ66095.1 - 5.3 6.9 31.9 6.2 6.7 31.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ66095.1 - 6.1 6.6 12.5 7.4 6.3 12.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ66095.1 - 6.5 5.5 10.3 7.3 5.3 10.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter R_equi_Vir PF05526.11 CDJ66095.1 - 7.7 6.3 9.5 10 5.9 9.5 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SKA1 PF07160.12 CDJ66095.1 - 7.7 6.3 16.9 9.2 6.0 16.9 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DDHD PF02862.17 CDJ66095.1 - 9.1 6.4 13.2 11 6.1 13.2 1.1 1 0 0 1 1 1 0 DDHD domain SPX PF03105.19 CDJ66096.1 - 2.1e-05 24.6 4.7 2.1e-05 24.6 4.7 1.1 1 0 0 1 1 1 1 SPX domain Sec3_C PF09763.9 CDJ66096.1 - 0.0091 14.4 1.4 0.0081 14.6 1.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Peroxin-3 PF04882.12 CDJ66096.1 - 0.22 10.5 9.0 0.28 10.2 9.0 1.1 1 0 0 1 1 1 0 Peroxin-3 BUD22 PF09073.10 CDJ66096.1 - 0.4 10.0 13.9 0.49 9.7 13.9 1.1 1 0 0 1 1 1 0 BUD22 Pannexin_like PF12534.8 CDJ66096.1 - 0.41 9.7 1.5 0.51 9.4 1.5 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Menin PF05053.13 CDJ66096.1 - 2 6.7 5.4 2.4 6.4 5.4 1.1 1 0 0 1 1 1 0 Menin Kinesin_assoc PF16183.5 CDJ66096.1 - 2.2 8.4 4.0 3 7.9 4.0 1.2 1 0 0 1 1 1 0 Kinesin-associated Macoilin PF09726.9 CDJ66096.1 - 9.3 4.7 26.5 11 4.4 26.5 1.1 1 0 0 1 1 1 0 Macoilin family DUF4614 PF15391.6 CDJ66096.1 - 9.6 6.2 30.5 14 5.7 30.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Mitofilin PF09731.9 CDJ66097.1 - 1.8e-05 23.8 0.0 1.8e-05 23.8 0.0 4.0 1 1 2 3 3 1 1 Mitochondrial inner membrane protein DUF5523 PF17661.1 CDJ66097.1 - 0.029 14.1 27.5 0.3 10.8 25.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Zip PF02535.22 CDJ66097.1 - 0.11 11.7 10.0 0.2 10.8 10.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter TT_ORF1 PF02956.14 CDJ66097.1 - 1.2 7.7 9.0 1.8 7.2 9.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 SID-1_RNA_chan PF13965.6 CDJ66097.1 - 1.4 7.2 5.9 1.9 6.8 5.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NPR3 PF03666.13 CDJ66097.1 - 1.6 7.4 20.0 0.87 8.3 17.8 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Otopetrin PF03189.13 CDJ66097.1 - 1.6 7.4 6.4 2.5 6.8 6.4 1.4 1 0 0 1 1 1 0 Otopetrin Tfb4 PF03850.14 CDJ66097.1 - 2.6 7.5 9.7 6.5 6.2 9.7 1.8 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF2151 PF10221.9 CDJ66097.1 - 2.7 6.5 12.4 4 5.9 12.4 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator Rgp1 PF08737.10 CDJ66097.1 - 4.7 6.3 15.1 7.2 5.7 15.1 1.4 1 0 0 1 1 1 0 Rgp1 Cellulose_synt PF03552.14 CDJ66097.1 - 6.2 5.2 7.6 9.6 4.6 7.6 1.2 1 0 0 1 1 1 0 Cellulose synthase Membralin PF09746.9 CDJ66097.1 - 8.7 5.3 12.5 16 4.4 12.5 1.4 1 0 0 1 1 1 0 Tumour-associated protein SelR PF01641.18 CDJ66098.1 - 5.8e-17 61.9 0.1 6.5e-17 61.7 0.1 1.0 1 0 0 1 1 1 1 SelR domain Pyr_redox_2 PF07992.14 CDJ66099.1 - 4.4e-36 124.6 0.0 5.3e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ66099.1 - 1.2e-15 57.8 1.3 6.3e-11 42.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ66099.1 - 7.4e-09 35.3 0.5 8.3e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ66099.1 - 4.9e-07 29.4 0.0 5.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CDJ66099.1 - 0.00032 20.1 0.4 0.43 9.8 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CDJ66099.1 - 0.00034 19.8 4.4 0.0023 17.1 3.1 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 CDJ66099.1 - 0.00049 19.5 0.3 0.36 10.2 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 CDJ66099.1 - 0.0011 17.8 0.7 0.026 13.3 0.9 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 CDJ66099.1 - 0.0012 18.0 2.3 0.045 12.8 1.8 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CDJ66099.1 - 0.0016 18.6 3.8 0.0022 18.2 0.6 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 CDJ66099.1 - 0.0019 18.6 0.5 2 8.9 0.1 2.8 2 1 0 3 3 3 2 Putative NAD(P)-binding K_oxygenase PF13434.6 CDJ66099.1 - 0.0059 15.8 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CDJ66099.1 - 0.0082 15.4 0.1 0.018 14.3 0.1 1.6 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 CDJ66099.1 - 0.01 15.8 3.6 0.55 10.1 0.0 2.9 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 CDJ66099.1 - 0.025 14.6 0.1 7.5 6.5 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 CDJ66099.1 - 0.093 12.0 1.3 2.9 7.0 0.4 2.3 2 0 0 2 2 2 0 FAD binding domain XdhC_C PF13478.6 CDJ66099.1 - 0.15 12.6 0.3 7.9 7.0 0.0 2.5 2 1 0 2 2 2 0 XdhC Rossmann domain F420_oxidored PF03807.17 CDJ66099.1 - 0.2 12.3 2.3 53 4.5 0.0 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 CDJ66099.1 - 0.24 10.8 3.9 2.7 7.4 1.1 2.5 3 0 0 3 3 3 0 short chain dehydrogenase Lycopene_cycl PF05834.12 CDJ66099.1 - 0.28 10.2 1.0 0.44 9.5 0.3 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 CDJ66099.1 - 0.38 10.3 7.4 0.079 12.5 2.5 2.1 2 1 0 3 3 3 0 FAD dependent oxidoreductase GATase PF00117.28 CDJ66101.1 - 2.7e-31 108.8 0.0 1.1e-30 106.9 0.0 2.0 2 1 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CDJ66101.1 - 3.3e-06 27.0 5.4 4.9e-06 26.5 0.2 3.2 2 1 0 2 2 2 1 Peptidase C26 NAD_synthase PF02540.17 CDJ66101.1 - 0.0005 19.3 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 CDJ66101.1 - 0.0012 17.7 0.0 0.0012 17.7 0.0 1.8 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.19 CDJ66101.1 - 0.023 14.7 0.2 0.21 11.6 0.0 2.3 3 0 0 3 3 3 0 Phosphoadenosine phosphosulfate reductase family DJ-1_PfpI PF01965.24 CDJ66101.1 - 0.026 14.3 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 DJ-1/PfpI family Asn_synthase PF00733.21 CDJ66101.1 - 0.041 13.5 3.9 0.042 13.5 0.0 2.5 3 0 0 3 3 3 0 Asparagine synthase RPA43_OB PF17875.1 CDJ66101.1 - 0.1 13.2 1.5 35 5.0 2.5 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Spt20 PF12090.8 CDJ66101.1 - 0.17 11.5 15.9 0.26 10.9 15.9 1.2 1 0 0 1 1 1 0 Spt20 family ThiI PF02568.14 CDJ66101.1 - 0.22 11.1 1.0 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) BBL5 PF07289.11 CDJ66101.1 - 0.25 10.4 2.7 0.42 9.6 2.7 1.3 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein NifQ PF04891.12 CDJ66101.1 - 0.35 11.2 4.7 0.89 9.9 4.7 1.6 1 0 0 1 1 1 0 NifQ Apt1 PF10351.9 CDJ66102.1 - 0.051 12.4 5.2 0.059 12.2 5.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.13 CDJ66102.1 - 0.15 12.6 14.6 0.23 12.0 14.6 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain SPX PF03105.19 CDJ66102.1 - 0.21 11.5 8.3 0.25 11.2 8.3 1.1 1 0 0 1 1 1 0 SPX domain CASP_C PF08172.12 CDJ66102.1 - 0.25 10.7 3.8 0.32 10.3 3.8 1.2 1 0 0 1 1 1 0 CASP C terminal CCDC106 PF15794.5 CDJ66102.1 - 0.72 9.5 7.6 1.1 9.0 7.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Lin-8 PF03353.15 CDJ66102.1 - 0.75 9.3 2.0 0.87 9.1 2.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ66102.1 - 0.99 7.9 9.1 1.3 7.5 9.1 1.2 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 CDJ66102.1 - 1.4 7.8 6.9 1.6 7.6 6.9 1.1 1 0 0 1 1 1 0 Mitoguardin DUF1631 PF07793.11 CDJ66102.1 - 7.1 4.9 7.7 8.8 4.6 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF4698 PF15769.5 CDJ66102.1 - 9.2 5.2 7.9 12 4.8 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) DUF2722 PF10846.8 CDJ66104.1 - 0.0014 17.7 2.6 0.0014 17.7 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ66104.1 - 0.009 15.6 8.4 0.012 15.2 8.4 1.3 1 0 0 1 1 1 1 Spt20 family Arm_3 PF16186.5 CDJ66104.1 - 0.023 14.3 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Atypical Arm repeat Pkinase PF00069.25 CDJ66105.1 - 6e-36 124.2 0.0 7.9e-26 91.0 0.0 4.5 4 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ66105.1 - 1.8e-13 50.4 0.0 2.3e-07 30.3 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase RskA PF10099.9 CDJ66105.1 - 0.00062 20.1 6.8 0.00062 20.1 6.8 8.5 4 2 4 8 8 8 2 Anti-sigma-K factor rskA HNOBA PF07701.14 CDJ66105.1 - 0.001 18.6 1.4 1.8 7.9 0.0 2.4 2 0 0 2 2 2 2 Heme NO binding associated DUF755 PF05501.11 CDJ66105.1 - 0.0048 17.2 2.1 0.0048 17.2 2.1 7.3 8 0 0 8 8 8 1 Domain of unknown function (DUF755) Seadorna_VP7 PF07387.11 CDJ66105.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 BAF1_ABF1 PF04684.13 CDJ66105.1 - 0.14 11.2 0.0 0.14 11.2 0.0 3.9 4 1 0 4 4 4 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ66105.1 - 0.81 8.4 25.2 0.99 8.1 0.7 3.3 3 0 0 3 3 3 0 Presenilin OATP PF03137.20 CDJ66105.1 - 1.3 7.2 7.6 0.37 9.0 0.1 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MAP7 PF05672.11 CDJ66105.1 - 8.6 6.0 39.9 7.8 6.2 8.2 2.8 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Pkinase PF00069.25 CDJ66106.1 - 6.3e-07 29.0 0.0 6.4e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ66106.1 - 0.0019 17.5 0.0 0.0029 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase BAF1_ABF1 PF04684.13 CDJ66106.1 - 0.055 12.5 0.0 0.055 12.5 0.0 1.8 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor OATP PF03137.20 CDJ66106.1 - 0.11 10.8 0.1 0.15 10.3 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Spt20 PF12090.8 CDJ66106.1 - 0.39 10.3 24.0 0.79 9.3 24.0 1.4 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ66106.1 - 0.55 11.2 6.4 0.15 13.0 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ66106.1 - 3.5 7.5 24.7 0.38 10.7 19.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ66106.1 - 5.4 5.8 22.7 9.6 5.0 22.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) EBP50_C PF09007.11 CDJ66106.1 - 6.8 7.7 11.4 0.34 11.9 1.1 2.8 3 0 0 3 3 3 0 EBP50, C-terminal DivIC PF04977.15 CDJ66106.1 - 8 6.3 16.0 0.092 12.5 8.4 1.6 2 0 0 2 2 2 0 Septum formation initiator DUF3008 PF11450.8 CDJ66108.1 - 0.03 14.5 0.0 0.038 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) COG6 PF06419.11 CDJ66109.1 - 9.4e-09 34.0 25.7 0.00012 20.4 6.7 4.8 3 2 1 4 4 4 3 Conserved oligomeric complex COG6 GhoS PF11080.8 CDJ66109.1 - 0.13 12.3 0.3 0.41 10.7 0.3 1.9 1 0 0 1 1 1 0 Endoribonuclease GhoS BP28CT PF08146.12 CDJ66109.1 - 0.33 10.8 0.0 0.33 10.8 0.0 4.2 5 0 0 5 5 5 0 BP28CT (NUC211) domain NOG1 PF06858.14 CDJ66109.1 - 0.47 10.3 6.7 2.6 7.9 0.4 3.8 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) DUF4680 PF15730.5 CDJ66110.1 - 0.046 14.1 0.3 0.07 13.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) SUIM_assoc PF16619.5 CDJ66111.1 - 0.032 14.3 47.1 0.038 14.1 12.0 3.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PP2C PF00481.21 CDJ66112.1 - 4.7e-13 49.4 0.2 5.3e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Atrophin-1 PF03154.15 CDJ66112.1 - 0.9 7.7 4.0 1.1 7.5 4.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family Spt20 PF12090.8 CDJ66113.1 - 2.8 7.5 41.0 2.8 7.5 41.0 1.0 1 0 0 1 1 1 0 Spt20 family Coilin_N PF15862.5 CDJ66113.1 - 7.1 6.4 15.5 8.6 6.2 15.5 1.2 1 0 0 1 1 1 0 Coilin N-terminus DUF3408 PF11888.8 CDJ66113.1 - 7.5 6.7 15.4 7.6 6.7 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF4770 PF15994.5 CDJ66113.1 - 8.4 6.6 16.0 8.8 6.5 16.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) HA2 PF04408.23 CDJ66113.1 - 10 6.5 8.3 11 6.4 8.3 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) His_Phos_1 PF00300.22 CDJ66114.1 - 4.8e-05 23.1 0.1 4.8e-05 23.1 0.1 2.9 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) TFIIA PF03153.13 CDJ66114.1 - 0.0035 17.4 11.0 0.0044 17.1 11.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ66114.1 - 0.042 13.4 9.8 0.071 12.7 9.8 1.3 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ66114.1 - 0.23 10.4 6.3 0.36 9.7 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Alpha_GJ PF03229.13 CDJ66114.1 - 1.2 9.7 19.9 2.1 8.9 19.9 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF4366 PF14283.6 CDJ66114.1 - 1.6 8.7 8.7 0.25 11.4 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) SR-25 PF10500.9 CDJ66115.1 - 2.7e-05 23.9 11.6 2.7e-05 23.9 11.6 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Utp21 PF04192.12 CDJ66115.1 - 0.0061 16.1 4.7 0.012 15.1 4.7 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain CCSAP PF15748.5 CDJ66115.1 - 0.012 15.8 10.7 0.012 15.8 10.7 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Peptidase_S64 PF08192.11 CDJ66115.1 - 0.11 11.0 5.6 0.17 10.4 5.6 1.3 1 0 0 1 1 1 0 Peptidase family S64 Jak1_Phl PF17887.1 CDJ66115.1 - 0.2 11.6 8.9 0.31 11.0 8.9 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain EFTUD2 PF16004.5 CDJ66115.1 - 0.51 10.9 7.5 0.055 14.1 2.8 1.7 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus MAJIN PF15077.6 CDJ66115.1 - 1.2 8.8 9.0 0.12 12.1 2.7 2.1 2 0 0 2 2 2 0 Membrane-anchored junction protein POP1 PF06978.11 CDJ66116.1 - 2.3e-10 40.8 12.4 2.5e-09 37.4 0.0 2.7 3 0 0 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CDJ66116.1 - 0.00042 20.6 7.9 0.0017 18.7 0.0 3.4 3 0 0 3 3 3 1 POPLD (NUC188) domain DUF2722 PF10846.8 CDJ66116.1 - 0.0083 15.1 17.9 0.4 9.6 12.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Innexin PF00876.18 CDJ66116.1 - 0.11 11.7 0.3 0.17 11.2 0.3 1.2 1 0 0 1 1 1 0 Innexin DDHD PF02862.17 CDJ66116.1 - 0.57 10.3 4.5 0.83 9.8 2.6 2.0 2 0 0 2 2 2 0 DDHD domain Neur_chan_memb PF02932.16 CDJ66116.1 - 1.1 9.3 3.9 2.1 8.4 2.7 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BTG PF07742.12 CDJ66116.1 - 1.1 9.1 3.9 2.8 7.8 3.9 1.6 1 0 0 1 1 1 0 BTG family Miga PF10265.9 CDJ66116.1 - 1.1 8.1 3.8 2.1 7.2 3.8 1.4 1 0 0 1 1 1 0 Mitoguardin Suf PF05843.14 CDJ66116.1 - 1.4 8.8 14.0 6.9 6.6 8.7 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) MAJIN PF15077.6 CDJ66116.1 - 1.8 8.3 8.4 4 7.2 8.4 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein Peptidase_S49_N PF08496.10 CDJ66116.1 - 2.6 8.1 10.6 0.95 9.5 7.2 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal GREB1 PF15782.5 CDJ66116.1 - 2.7 5.0 4.9 3.6 4.6 4.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 CDJ66116.1 - 4.2 6.9 39.4 2.4 7.7 6.8 2.1 2 0 0 2 2 2 0 Spt20 family XRN_M PF17846.1 CDJ66116.1 - 5.7 5.8 5.3 11 4.9 5.3 1.3 1 0 0 1 1 1 0 Xrn1 helical domain PAT1 PF09770.9 CDJ66116.1 - 7.9 4.6 19.6 0.81 7.9 11.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 EF-hand_6 PF13405.6 CDJ66120.1 - 3.8e-09 35.7 0.6 4.3e-06 26.2 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 CDJ66120.1 - 6.2e-09 34.8 0.1 4.3e-06 25.9 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 CDJ66120.1 - 2.6e-06 27.8 0.0 0.0015 18.9 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair RskA PF10099.9 CDJ66120.1 - 2.3e-05 24.8 1.3 2.3e-05 24.8 1.3 4.5 2 1 1 3 3 3 1 Anti-sigma-K factor rskA EF-hand_8 PF13833.6 CDJ66120.1 - 0.00066 19.5 0.0 2 8.4 0.0 2.9 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ66120.1 - 0.0012 18.3 1.8 0.0029 17.0 0.0 2.5 3 0 0 3 3 3 1 EF hand DUF4064 PF13273.6 CDJ66120.1 - 2.3 8.6 0.0 2.3 8.6 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) DUF2914 PF11141.8 CDJ66122.1 - 0.031 14.0 0.1 0.053 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) Coa1 PF08695.10 CDJ66122.1 - 0.21 11.3 0.5 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Cytochrome oxidase complex assembly protein 1 DUF5588 PF17826.1 CDJ66122.1 - 8.7 5.1 6.2 12 4.6 6.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5588) TFIIA PF03153.13 CDJ66124.1 - 0.073 13.1 6.9 0.1 12.6 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ66124.1 - 0.081 13.2 11.3 0.19 12.0 10.8 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ66124.1 - 0.29 10.3 6.6 0.51 9.5 6.6 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region Spt20 PF12090.8 CDJ66124.1 - 0.32 10.6 5.3 0.55 9.8 5.3 1.3 1 0 0 1 1 1 0 Spt20 family Fes1 PF08609.10 CDJ66124.1 - 0.72 10.8 3.4 1.1 10.2 1.1 2.3 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 SUIM_assoc PF16619.5 CDJ66124.1 - 2.1 8.5 13.4 4.5 7.4 13.4 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Tom37 PF10568.9 CDJ66125.1 - 0.031 14.6 0.1 0.061 13.6 0.1 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein ATP_bind_2 PF03668.15 CDJ66125.1 - 0.094 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop ATPase protein family IMUP PF15761.5 CDJ66125.1 - 0.8 10.4 11.5 1.7 9.4 11.5 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ66125.1 - 0.87 9.1 19.1 1.7 8.2 19.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ66125.1 - 2.6 7.9 16.1 0.07 13.1 2.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CcmD PF04995.14 CDJ66126.1 - 0.0019 18.2 4.3 0.0019 18.2 4.3 8.4 4 2 0 4 4 4 1 Heme exporter protein D (CcmD) TMEM51 PF15345.6 CDJ66126.1 - 0.002 18.0 10.1 0.002 18.0 10.1 5.2 3 2 1 4 4 4 1 Transmembrane protein 51 SR-25 PF10500.9 CDJ66126.1 - 0.0025 17.4 19.8 0.0025 17.4 19.8 4.0 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein LRR_4 PF12799.7 CDJ66127.1 - 7.9e-14 51.6 25.3 3.1e-06 27.4 1.9 4.3 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ66127.1 - 1e-13 50.8 18.6 3.6e-07 29.9 6.0 4.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 CDJ66127.1 - 1.5e-05 24.7 15.1 0.25 11.5 0.1 5.9 6 1 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 CDJ66127.1 - 4.2e-05 23.1 5.1 0.01 15.3 0.6 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CDJ66127.1 - 0.074 13.6 0.7 0.074 13.6 0.7 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat DUF2057 PF09829.9 CDJ66127.1 - 1.7 8.8 9.4 0.12 12.5 2.8 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) PIP5K PF01504.18 CDJ66128.1 - 7.3e-72 241.9 0.3 1.4e-71 241.0 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_1 PF00036.32 CDJ66128.1 - 8.3e-05 21.9 0.2 0.00036 19.9 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CDJ66128.1 - 0.0015 18.9 0.2 0.0066 16.9 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ66128.1 - 0.0074 16.1 0.0 0.029 14.3 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain RBM39linker PF15519.6 CDJ66129.1 - 3.6e-07 31.2 5.6 3.8e-07 31.1 0.4 2.3 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_1 PF00076.22 CDJ66129.1 - 7.2e-07 28.9 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 CDJ66129.1 - 0.006 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Lipoprotein_8 PF02030.15 CDJ66129.1 - 0.011 14.4 0.1 0.013 14.3 0.1 1.1 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) RRM_1 PF00076.22 CDJ66130.1 - 3.7e-25 87.5 0.0 1.7e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ66130.1 - 0.0026 17.6 0.0 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF4471 PF14740.6 CDJ66131.1 - 0.00027 20.3 5.6 0.00027 20.3 5.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4471) SID-1_RNA_chan PF13965.6 CDJ66131.1 - 0.011 14.2 2.8 0.017 13.6 2.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Plasmodium_Vir PF05795.11 CDJ66131.1 - 0.025 14.0 2.1 0.034 13.6 2.1 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1980 PF09323.10 CDJ66131.1 - 0.061 13.2 10.2 0.032 14.2 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF3405 PF11885.8 CDJ66131.1 - 0.07 11.7 13.1 0.12 11.0 13.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Velvet PF11754.8 CDJ66131.1 - 0.088 12.7 18.2 0.015 15.2 9.8 2.1 2 0 0 2 2 2 0 Velvet factor SLC12 PF03522.15 CDJ66131.1 - 0.3 10.1 17.2 0.018 14.1 10.5 1.9 2 0 0 2 2 2 0 Solute carrier family 12 FAM60A PF15396.6 CDJ66131.1 - 0.38 10.7 14.3 0.15 12.0 9.3 2.2 2 0 0 2 2 2 0 Protein Family FAM60A eIF-3_zeta PF05091.12 CDJ66131.1 - 0.44 9.5 26.0 0.041 12.9 18.9 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) O-antigen_lig PF13425.6 CDJ66131.1 - 0.68 8.7 3.7 1 8.1 3.7 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Neur_chan_memb PF02932.16 CDJ66131.1 - 0.73 9.9 17.5 0.22 11.5 11.3 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Rxt3 PF08642.10 CDJ66131.1 - 1 10.2 9.0 0.18 12.5 3.7 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Nha1_C PF08619.10 CDJ66131.1 - 1.1 8.4 22.6 0.094 11.9 13.2 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF913 PF06025.12 CDJ66131.1 - 1.1 8.1 12.0 0.12 11.3 7.4 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SpoIIP PF07454.11 CDJ66131.1 - 1.2 8.5 21.1 0.036 13.5 14.2 1.8 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF3408 PF11888.8 CDJ66131.1 - 1.4 9.0 18.9 0.14 12.3 13.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) TCP PF03634.13 CDJ66131.1 - 1.6 9.3 20.8 0.59 10.7 13.3 2.3 2 0 0 2 2 2 0 TCP family transcription factor Dynamin_N PF00350.23 CDJ66131.1 - 2.1 8.4 8.2 1.2 9.1 5.9 1.8 2 0 0 2 2 2 0 Dynamin family Presenilin PF01080.17 CDJ66131.1 - 2.2 6.9 24.8 0.048 12.4 15.7 2.0 2 0 0 2 2 2 0 Presenilin Pinin_SDK_memA PF04696.13 CDJ66131.1 - 2.2 8.3 42.3 0.35 10.9 31.6 2.5 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region LptF_LptG PF03739.14 CDJ66131.1 - 2.3 7.0 5.4 3.6 6.3 5.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG EOS1 PF12326.8 CDJ66131.1 - 2.8 7.8 10.0 1.8 8.5 7.2 1.9 2 0 0 2 2 2 0 N-glycosylation protein CPSF100_C PF13299.6 CDJ66131.1 - 3.1 8.0 21.3 0.033 14.4 9.8 2.3 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EPL1 PF10513.9 CDJ66131.1 - 3.2 8.1 20.8 0.19 12.1 12.7 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like FAM176 PF14851.6 CDJ66131.1 - 3.4 7.3 14.2 0.26 11.0 8.3 2.2 2 0 0 2 2 2 0 FAM176 family Baculo_PP31 PF05311.11 CDJ66131.1 - 3.9 6.9 18.2 0.95 8.9 12.1 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Connexin PF00029.19 CDJ66131.1 - 4 7.1 17.9 0.26 11.0 12.1 1.8 2 0 0 2 2 2 0 Connexin DUF702 PF05142.12 CDJ66131.1 - 4 7.9 27.8 0.36 11.3 18.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF702) RR_TM4-6 PF06459.12 CDJ66131.1 - 4 7.2 20.2 0.6 9.9 14.7 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Cellulose_synt PF03552.14 CDJ66131.1 - 4.1 5.8 6.5 6 5.2 6.5 1.3 1 0 0 1 1 1 0 Cellulose synthase Paf1 PF03985.13 CDJ66131.1 - 4.6 6.1 21.5 0.19 10.7 15.7 1.5 2 0 0 2 2 2 0 Paf1 TFB6 PF17110.5 CDJ66131.1 - 4.9 6.9 10.7 1.5 8.5 7.5 1.8 2 0 0 2 2 1 0 Subunit 11 of the general transcription factor TFIIH Folate_carrier PF01770.18 CDJ66131.1 - 5 5.7 11.4 10 4.7 11.4 1.4 1 0 0 1 1 1 0 Reduced folate carrier Zip PF02535.22 CDJ66131.1 - 5.2 6.2 8.7 12 5.0 8.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2828 PF11443.8 CDJ66131.1 - 5.2 5.0 20.2 0.053 11.6 12.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Tim54 PF11711.8 CDJ66131.1 - 6.1 5.5 18.5 0.34 9.6 13.1 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF2464 PF10240.9 CDJ66131.1 - 6.1 6.3 14.1 0.93 9.0 9.5 1.9 2 0 0 2 2 2 0 Multivesicular body subunit 12 DUF1266 PF06889.11 CDJ66131.1 - 8.3 6.4 22.9 0.53 10.3 16.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Membralin PF09746.9 CDJ66131.1 - 9.5 5.1 13.5 0.22 10.5 7.0 1.6 2 0 0 2 2 2 0 Tumour-associated protein Myb_DNA-bind_7 PF15963.5 CDJ66132.1 - 3.6e-09 36.4 1.4 0.0026 17.6 0.2 2.5 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-binding PF00249.31 CDJ66132.1 - 4.2e-07 30.0 0.0 0.044 14.0 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain GNAT_C PF18164.1 CDJ66132.1 - 0.00026 20.7 0.1 0.16 11.7 0.0 2.3 2 0 0 2 2 2 2 GNAT-like C-terminal domain DUF2989 PF11207.8 CDJ66132.1 - 0.0034 17.2 0.4 3.6 7.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2989) BAT2_N PF07001.11 CDJ66132.1 - 0.013 16.0 4.6 1.8 9.0 0.6 2.1 2 0 0 2 2 2 0 BAT2 N-terminus Glyco_transf_49 PF13896.6 CDJ66132.1 - 0.032 13.6 1.0 4.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl-transferase for dystroglycan SUIM_assoc PF16619.5 CDJ66132.1 - 0.038 14.0 9.6 0.48 10.5 0.3 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3091 PF11291.8 CDJ66132.1 - 0.066 13.4 1.2 13 6.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) Wyosine_form PF08608.12 CDJ66132.1 - 0.15 12.4 0.0 40 4.7 0.0 2.6 2 0 0 2 2 2 0 Wyosine base formation DUF393 PF04134.12 CDJ66132.1 - 0.16 13.3 0.4 34 5.8 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function, DUF393 Guanylate_kin PF00625.21 CDJ66132.1 - 0.2 11.3 0.3 24 4.5 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase FANC_SAP PF18081.1 CDJ66132.1 - 1 9.5 9.8 9.1 6.5 0.5 2.6 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain K_channel_TID PF07941.11 CDJ66132.1 - 1.2 9.6 20.9 0.36 11.3 9.5 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Intimin_C PF07979.11 CDJ66132.1 - 1.6 9.2 3.5 22 5.6 0.1 3.4 4 1 1 5 5 5 0 Intimin C-type lectin domain Surface_antigen PF11054.8 CDJ66133.1 - 1.6e-27 96.8 5.1 4.5e-24 85.5 1.0 2.1 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen Imm74 PF15603.6 CDJ66133.1 - 0.18 12.0 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 74 Ank_4 PF13637.6 CDJ66134.1 - 8.9e-19 67.6 1.7 6.1e-08 33.1 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ66134.1 - 5.6e-17 62.1 0.2 1.4e-11 44.8 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ66134.1 - 3.6e-16 58.8 2.0 0.00046 20.5 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CDJ66134.1 - 4.4e-12 45.1 2.2 0.014 15.8 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CDJ66134.1 - 3.8e-09 36.6 0.2 2.5e-06 27.7 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Menin PF05053.13 CDJ66134.1 - 0.082 11.3 1.8 0.11 10.8 1.8 1.1 1 0 0 1 1 1 0 Menin Plasmodium_Vir PF05795.11 CDJ66134.1 - 1.1 8.6 4.4 1.6 8.1 4.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 CDJ66134.1 - 3.2 6.4 6.1 4.5 5.9 6.1 1.1 1 0 0 1 1 1 0 Presenilin DASH_Hsk3 PF08227.11 CDJ66136.1 - 0.015 15.7 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like NUDIX PF00293.28 CDJ66137.1 - 6.2e-15 55.4 0.1 1.1e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Utp14 PF04615.13 CDJ66137.1 - 0.36 9.3 25.8 0.45 9.0 25.8 1.4 1 0 0 1 1 1 0 Utp14 protein MAM33 PF02330.16 CDJ66138.1 - 1e-25 91.0 0.8 3.8e-25 89.1 0.8 1.8 1 1 0 1 1 1 1 Mitochondrial glycoprotein zf-C2H2_8 PF15909.5 CDJ66138.1 - 0.013 15.8 0.6 0.33 11.3 0.1 2.4 2 1 0 2 2 2 0 C2H2-type zinc ribbon Cauli_DNA-bind PF03310.13 CDJ66138.1 - 0.1 12.6 0.3 0.18 11.9 0.3 1.3 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein SOBP PF15279.6 CDJ66139.1 - 0.16 12.6 42.7 0.21 12.1 42.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SOG2 PF10428.9 CDJ66139.1 - 0.66 9.1 51.7 0.9 8.7 51.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 CDJ66139.1 - 8.7 4.9 44.9 11 4.5 44.9 1.0 1 0 0 1 1 1 0 Hamartin protein Peroxin-13_N PF04088.13 CDJ66140.1 - 0.29 11.4 13.0 0.31 11.3 13.0 1.0 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4820 PF16091.5 CDJ66140.1 - 0.76 9.1 14.7 0.92 8.8 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SpoIIP PF07454.11 CDJ66140.1 - 1.1 8.7 22.9 1.1 8.6 22.9 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDJ66140.1 - 1.3 8.8 19.4 1.3 8.8 19.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3408 PF11888.8 CDJ66140.1 - 1.3 9.2 19.8 1.4 9.1 19.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) AIF_C PF14721.6 CDJ66140.1 - 1.4 9.3 15.9 1.5 9.2 15.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CobT PF06213.12 CDJ66140.1 - 1.4 8.3 29.0 1.5 8.2 29.0 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PRC2_HTH_1 PF18118.1 CDJ66140.1 - 1.5 9.7 14.7 1.6 9.6 14.7 1.1 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Presenilin PF01080.17 CDJ66140.1 - 1.5 7.5 23.4 1.5 7.5 23.4 1.0 1 0 0 1 1 1 0 Presenilin Eapp_C PF10238.9 CDJ66140.1 - 1.5 8.9 20.0 1.7 8.7 20.0 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein TetR_C_23 PF17931.1 CDJ66140.1 - 1.7 8.8 9.9 1.8 8.7 9.9 1.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Coilin_N PF15862.5 CDJ66140.1 - 1.7 8.4 23.3 2.6 7.8 23.3 1.3 1 0 0 1 1 1 0 Coilin N-terminus PPL5 PF18168.1 CDJ66140.1 - 1.7 7.8 14.5 1.8 7.8 14.5 1.0 1 0 0 1 1 1 0 Prim-pol family 5 CLN3 PF02487.17 CDJ66140.1 - 1.8 7.5 17.8 1.8 7.5 17.8 1.0 1 0 0 1 1 1 0 CLN3 protein Connexin PF00029.19 CDJ66140.1 - 2.9 7.6 16.9 2.9 7.6 16.9 1.0 1 0 0 1 1 1 0 Connexin DUF5308 PF17233.2 CDJ66140.1 - 2.9 8.1 17.6 3 8.1 17.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DDHD PF02862.17 CDJ66140.1 - 3.3 7.8 20.2 3.2 7.8 20.2 1.0 1 0 0 1 1 1 0 DDHD domain TFB6 PF17110.5 CDJ66140.1 - 3.4 7.4 13.6 3.7 7.2 13.6 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Pex14_N PF04695.13 CDJ66140.1 - 3.7 8.2 33.1 3.8 8.2 33.1 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gti1_Pac2 PF09729.9 CDJ66140.1 - 3.9 7.5 16.8 4 7.5 16.8 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family G0-G1_switch_2 PF15103.6 CDJ66140.1 - 4.3 7.8 15.3 5.7 7.4 15.3 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 CPSF100_C PF13299.6 CDJ66140.1 - 4.4 7.4 18.3 4.7 7.4 18.3 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ORC_WH_C PF18137.1 CDJ66140.1 - 4.6 7.3 20.4 5.4 7.1 20.4 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF2828 PF11443.8 CDJ66140.1 - 4.6 5.2 20.6 4.9 5.1 20.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) HNOBA PF07701.14 CDJ66140.1 - 5 6.5 19.4 5.6 6.3 19.4 1.0 1 0 0 1 1 1 0 Heme NO binding associated DUF1764 PF08576.10 CDJ66140.1 - 5.3 8.0 18.3 5.8 7.9 18.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) MDM31_MDM32 PF08118.11 CDJ66140.1 - 6 5.4 16.6 6.1 5.4 16.6 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Paf1 PF03985.13 CDJ66140.1 - 6.3 5.7 24.0 6.6 5.6 24.0 1.0 1 0 0 1 1 1 0 Paf1 Sec62 PF03839.16 CDJ66140.1 - 6.4 6.2 17.3 6.6 6.2 17.3 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 CDJ66140.1 - 6.5 5.4 19.9 6.9 5.3 19.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.6 CDJ66140.1 - 6.6 6.4 14.5 7.3 6.2 14.5 1.1 1 0 0 1 1 1 0 FAM176 family DUF4770 PF15994.5 CDJ66140.1 - 6.8 6.9 22.5 9.6 6.4 22.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Baculo_PP31 PF05311.11 CDJ66140.1 - 6.8 6.1 20.8 7.2 6.0 20.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) eIF-3_zeta PF05091.12 CDJ66140.1 - 7 5.5 29.5 6.9 5.5 29.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CCDC53 PF10152.9 CDJ66140.1 - 7 7.0 22.8 7.5 7.0 22.8 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex GOLD_2 PF13897.6 CDJ66140.1 - 7.4 7.1 7.3 8.7 6.8 7.3 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CDC45 PF02724.14 CDJ66140.1 - 7.7 4.7 17.6 7.7 4.7 17.6 1.0 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ66140.1 - 9.3 5.2 21.9 9.4 5.1 21.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CSG2 PF16965.5 CDJ66140.1 - 9.6 5.0 14.0 9.7 5.0 14.0 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator DUF3276 PF11680.8 CDJ66140.1 - 9.7 6.3 15.6 12 6.1 15.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Slu7 PF11708.8 CDJ66141.1 - 1.8e-70 237.7 39.3 1.6e-63 215.0 13.2 3.0 2 2 1 3 3 3 2 Pre-mRNA splicing Prp18-interacting factor RskA PF10099.9 CDJ66141.1 - 0.011 16.1 42.1 0.013 15.8 0.2 3.7 1 1 2 3 3 3 0 Anti-sigma-K factor rskA Rrn6 PF10214.9 CDJ66141.1 - 0.45 9.0 19.5 0.63 8.5 19.5 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TAF4 PF05236.14 CDJ66141.1 - 1.3 8.7 34.5 4.6 6.9 0.3 2.6 1 1 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family TFIIA PF03153.13 CDJ66141.1 - 1.9 8.4 36.8 0.066 13.2 30.5 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cytomega_UL20A PF05984.12 CDJ66141.1 - 2.8 8.3 5.7 4.2 7.7 0.1 2.7 3 0 0 3 3 3 0 Cytomegalovirus UL20A protein Retrotrans_gag PF03732.17 CDJ66142.1 - 0.00014 22.0 0.1 0.0011 19.2 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein Peroxin-3 PF04882.12 CDJ66143.1 - 4.3e-06 26.0 15.5 0.0021 17.1 0.0 3.2 1 1 2 3 3 3 2 Peroxin-3 RskA PF10099.9 CDJ66143.1 - 0.025 14.9 1.8 0.025 14.9 1.8 5.2 1 1 3 5 5 5 0 Anti-sigma-K factor rskA Dpy19 PF10034.9 CDJ66143.1 - 0.1 10.8 3.6 0.18 10.0 3.6 1.3 1 0 0 1 1 1 0 Q-cell neuroblast polarisation 7tm_1 PF00001.21 CDJ66143.1 - 0.23 10.7 1.0 0.4 10.0 1.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) MBR1 PF17058.5 CDJ66143.1 - 0.33 11.2 3.3 0.7 10.2 3.3 1.6 1 1 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 TMEM65 PF10507.9 CDJ66144.1 - 1.8e-39 134.0 0.1 1.8e-39 134.0 0.1 2.9 2 1 0 2 2 2 1 Transmembrane protein 65 GAF PF01590.26 CDJ66144.1 - 1.3e-05 25.9 0.1 0.0027 18.3 0.1 3.1 1 1 0 1 1 1 1 GAF domain TMEM117 PF15113.6 CDJ66144.1 - 0.04 12.9 1.8 0.062 12.2 1.8 1.1 1 0 0 1 1 1 0 TMEM117 protein family UPF0016 PF01169.19 CDJ66144.1 - 3.5 8.0 7.3 0.26 11.6 1.3 2.3 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 Peptidase_S64 PF08192.11 CDJ66145.1 - 2.6 6.4 8.3 3.8 5.9 8.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Agouti PF05039.12 CDJ66145.1 - 4.2 8.1 13.3 3.7 8.3 9.0 2.8 2 0 0 2 2 2 0 Agouti protein PAC3 PF10178.9 CDJ66146.1 - 0.00031 20.8 0.0 0.00044 20.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Usher_TcfC PF17271.2 CDJ66146.1 - 0.9 8.3 8.2 1.1 7.9 8.2 1.0 1 0 0 1 1 1 0 TcfC Usher-like barrel domain DUF1180 PF06679.12 CDJ66146.1 - 5.5 7.4 7.2 8.1 6.8 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Maf PF02545.14 CDJ66147.1 - 1e-22 80.7 1.6 1.3e-21 77.1 1.6 2.1 1 1 0 1 1 1 1 Maf-like protein Lin-8 PF03353.15 CDJ66147.1 - 4.3 6.8 18.6 6.1 6.3 0.0 3.1 1 1 2 3 3 3 0 Ras-mediated vulval-induction antagonist GATA PF00320.27 CDJ66148.1 - 3.9e-08 32.8 3.5 1.1e-07 31.3 3.5 1.8 1 0 0 1 1 1 1 GATA zinc finger Pyrophosphatase PF00719.19 CDJ66149.1 - 8e-11 42.0 0.0 1.4e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Inorganic pyrophosphatase Shisa PF13908.6 CDJ66149.1 - 0.0006 20.1 3.5 0.0013 19.0 3.5 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator V_ATPase_I PF01496.19 CDJ66149.1 - 0.0012 16.9 0.5 0.0016 16.5 0.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GAPT PF11770.8 CDJ66149.1 - 0.0023 17.8 0.1 0.0037 17.1 0.1 1.2 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) Mucin PF01456.17 CDJ66149.1 - 0.0031 17.5 3.6 0.0031 17.5 3.6 3.2 2 1 1 3 3 1 1 Mucin-like glycoprotein WBP-1 PF11669.8 CDJ66149.1 - 0.0049 17.5 0.1 0.0049 17.5 0.1 2.3 1 1 1 2 2 2 1 WW domain-binding protein 1 Neur_chan_memb PF02932.16 CDJ66149.1 - 0.007 16.5 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ66149.1 - 0.007 16.4 0.9 0.011 15.8 0.9 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Pex14_N PF04695.13 CDJ66149.1 - 0.013 16.2 8.1 0.013 16.2 8.1 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.17 CDJ66149.1 - 0.014 15.6 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 DDHD domain DUF4834 PF16118.5 CDJ66149.1 - 0.014 16.3 6.4 0.1 13.6 6.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Tmemb_9 PF05434.11 CDJ66149.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 TMEM9 RNA_pol_Rpc4 PF05132.14 CDJ66149.1 - 0.042 14.3 0.1 0.042 14.3 0.1 2.2 3 0 0 3 3 3 0 RNA polymerase III RPC4 Ctr PF04145.15 CDJ66149.1 - 0.11 13.1 1.3 0.31 11.7 1.3 1.8 1 0 0 1 1 1 0 Ctr copper transporter family SID-1_RNA_chan PF13965.6 CDJ66149.1 - 0.14 10.6 0.2 0.18 10.1 0.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 CDJ66149.1 - 2.3 6.9 7.6 3.5 6.3 7.6 1.2 1 0 0 1 1 1 0 Presenilin TssO PF17561.2 CDJ66149.1 - 8.9 6.4 6.0 0.52 10.4 0.1 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO Herpes_UL52 PF03121.15 CDJ66150.1 - 3.7e-11 42.8 0.1 1.1e-10 41.3 0.1 1.8 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Mem_trans PF03547.18 CDJ66150.1 - 4.2 5.6 17.5 0.24 9.8 0.1 3.4 3 0 0 3 3 3 0 Membrane transport protein BSP_II PF05432.11 CDJ66151.1 - 8.8 5.9 12.1 20 4.8 12.0 1.5 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF5576 PF17739.1 CDJ66154.1 - 0.2 11.8 4.0 0.3 11.2 4.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5576) NEMP PF10225.9 CDJ66155.1 - 0.023 14.4 1.5 0.038 13.7 1.5 1.3 1 0 0 1 1 1 0 NEMP family SR-25 PF10500.9 CDJ66155.1 - 0.42 10.2 15.7 0.66 9.5 15.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 CDJ66156.1 - 0.27 11.1 19.6 0.28 11.0 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) Secretin_N_2 PF07655.13 CDJ66156.1 - 1.7 9.2 42.4 2.1 9.0 13.9 3.4 3 0 0 3 3 3 0 Secretin N-terminal domain Inositol_P PF00459.25 CDJ66157.1 - 4.5e-15 55.9 0.2 4.5e-15 55.9 0.2 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family SR-25 PF10500.9 CDJ66157.1 - 0.0043 16.7 10.1 0.0065 16.1 10.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ66157.1 - 0.045 14.4 7.1 0.045 14.4 7.1 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein Glyco_hydro_3_C PF01915.22 CDJ66157.1 - 0.069 13.1 0.5 0.081 12.9 0.5 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain RAP1 PF07218.11 CDJ66157.1 - 2.9 6.0 4.9 4.3 5.5 4.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.13 CDJ66157.1 - 3.6 5.5 10.9 4.2 5.3 10.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Herpes_pp85 PF04637.12 CDJ66157.1 - 5.3 5.3 5.8 8.1 4.7 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Inositol_P PF00459.25 CDJ66158.1 - 1.5e-19 70.6 0.1 2.9e-19 69.6 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family SSP160 PF06933.11 CDJ66158.1 - 0.13 10.4 18.7 0.17 10.0 18.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RAP1 PF07218.11 CDJ66158.1 - 0.64 8.2 15.1 0.83 7.9 15.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IQCJ-SCHIP1 PF15157.6 CDJ66158.1 - 0.71 9.7 7.5 1.3 8.9 7.5 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Macoilin PF09726.9 CDJ66158.1 - 6.2 5.2 11.2 8.2 4.8 11.2 1.1 1 0 0 1 1 1 0 Macoilin family IMCp PF12314.8 CDJ66160.1 - 2.9e-12 46.7 51.2 1e-08 35.3 33.3 3.2 1 1 2 3 3 3 3 Inner membrane complex protein TFIIA PF03153.13 CDJ66160.1 - 0.0094 16.0 8.3 0.0094 16.0 8.3 3.1 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF1645 PF07816.11 CDJ66160.1 - 0.069 13.7 15.0 1.3 9.6 8.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) PAP1 PF08601.10 CDJ66160.1 - 0.76 9.4 17.5 0.44 10.2 4.2 2.4 2 0 0 2 2 2 0 Transcription factor PAP1 SOG2 PF10428.9 CDJ66160.1 - 1.6 7.9 12.2 1.5 7.9 6.4 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein GREB1 PF15782.5 CDJ66160.1 - 1.6 5.7 12.7 0.12 9.5 4.2 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Ribosomal_60s PF00428.19 CDJ66160.1 - 6.4 7.4 7.7 0.65 10.6 1.1 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF755 PF05501.11 CDJ66160.1 - 8.6 6.7 42.0 0.1 12.9 16.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF755) HNOBA PF07701.14 CDJ66161.1 - 0.0047 16.4 0.9 0.85 9.0 0.0 2.1 2 0 0 2 2 2 2 Heme NO binding associated DUF2722 PF10846.8 CDJ66161.1 - 0.0059 15.6 6.7 0.0059 15.6 6.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) CFIA_Pcf11 PF11526.8 CDJ66161.1 - 0.0068 16.9 0.0 0.0068 16.9 0.0 2.5 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 DDHD PF02862.17 CDJ66161.1 - 0.0085 16.3 3.8 1 9.5 1.0 2.2 2 0 0 2 2 2 2 DDHD domain Gti1_Pac2 PF09729.9 CDJ66161.1 - 0.012 15.8 1.7 1.7 8.7 1.3 2.0 2 0 0 2 2 2 0 Gti1/Pac2 family ABC2_membrane_2 PF12679.7 CDJ66161.1 - 0.026 13.8 0.3 3.7 6.7 1.0 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein SpvB PF03534.13 CDJ66161.1 - 0.046 12.9 0.0 0.046 12.9 0.0 2.0 2 0 0 2 2 2 0 Salmonella virulence plasmid 65kDa B protein BRF1 PF07741.13 CDJ66161.1 - 0.22 11.9 14.9 0.24 11.8 0.3 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF702 PF05142.12 CDJ66161.1 - 0.31 11.5 17.5 1.1 9.7 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Spt20 PF12090.8 CDJ66161.1 - 0.48 10.0 56.3 1.3 8.6 20.4 2.1 2 0 0 2 2 2 0 Spt20 family RNase_H2_suC PF08615.11 CDJ66161.1 - 0.53 10.4 6.2 1.8 8.7 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Presenilin PF01080.17 CDJ66161.1 - 0.62 8.8 13.8 0.77 8.5 0.1 2.1 2 0 0 2 2 2 0 Presenilin RLL PF10036.9 CDJ66161.1 - 1.1 9.0 18.5 0.16 11.8 1.5 2.1 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein EPL1 PF10513.9 CDJ66161.1 - 1.7 9.1 16.2 0.8 10.1 0.3 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like TERB2 PF15101.6 CDJ66161.1 - 2.5 8.1 25.8 0.99 9.4 4.4 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF2828 PF11443.8 CDJ66161.1 - 4.3 5.3 10.7 4.2 5.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) SpoIIP PF07454.11 CDJ66161.1 - 4.6 6.6 16.3 3.6 7.0 1.2 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TCP PF03634.13 CDJ66161.1 - 5.1 7.6 16.5 2.7 8.5 0.1 2.2 2 0 0 2 2 2 0 TCP family transcription factor Pol_alpha_B_N PF08418.10 CDJ66161.1 - 7.5 6.4 13.4 6.1 6.7 5.9 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Velvet PF11754.8 CDJ66161.1 - 9.4 6.1 15.3 8.1 6.3 0.2 2.2 2 0 0 2 2 2 0 Velvet factor CDC45 PF02724.14 CDJ66161.1 - 10 4.3 10.4 9.2 4.4 0.0 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF4392 PF14336.6 CDJ66162.1 - 2.4e-24 86.3 0.1 8e-21 74.7 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4392) SUIM_assoc PF16619.5 CDJ66162.1 - 0.051 13.6 5.2 0.12 12.5 5.2 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 7tm_7 PF08395.12 CDJ66162.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor COX14 PF14880.6 CDJ66162.1 - 0.22 11.4 0.2 0.42 10.5 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Spt20 PF12090.8 CDJ66162.1 - 0.51 9.9 5.9 0.11 12.1 2.9 1.4 2 0 0 2 2 2 0 Spt20 family DUF2076 PF09849.9 CDJ66163.1 - 0.97 9.4 26.4 0.92 9.5 14.7 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TFIIA PF03153.13 CDJ66163.1 - 9.3 6.1 22.7 17 5.2 22.7 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IHABP4_N PF16174.5 CDJ66164.1 - 0.3 11.7 7.8 0.49 11.0 7.8 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal FAM199X PF15814.5 CDJ66164.1 - 5 6.1 5.7 7.3 5.5 5.7 1.3 1 0 0 1 1 1 0 Protein family FAM199X PAP_central PF04928.17 CDJ66165.1 - 1.2e-82 276.7 0.0 2.2e-82 275.8 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CDJ66165.1 - 5.6e-13 48.9 1.1 1.5e-08 34.5 0.4 2.8 3 0 0 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CDJ66165.1 - 7.5e-09 35.8 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 CDJ66165.1 - 0.00019 21.2 0.1 0.0004 20.2 0.1 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain Adeno_PV PF03910.13 CDJ66165.1 - 2.7 6.6 6.4 1.6 7.4 0.1 2.2 2 0 0 2 2 2 0 Adenovirus minor core protein PV Ribosomal_60s PF00428.19 CDJ66165.1 - 9.6 6.9 37.8 0.25 11.9 9.6 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ66166.1 - 0.01 16.2 18.2 0.01 16.2 18.2 1.6 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF2380 PF09533.10 CDJ66166.1 - 0.089 12.4 5.4 0.03 13.9 2.1 1.7 1 1 1 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) DUF4746 PF15928.5 CDJ66166.1 - 0.098 12.1 7.0 0.096 12.1 7.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Mgr1 PF08602.10 CDJ66166.1 - 0.96 8.2 6.6 1.1 8.0 6.6 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Saw1 PF11561.8 CDJ66166.1 - 1.1 8.8 11.9 1.2 8.6 11.9 1.0 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Ribosomal_60s PF00428.19 CDJ66166.1 - 1.2 9.8 13.7 1 10.0 8.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ66166.1 - 3.5 7.5 32.8 4.2 7.2 32.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PXA PF02194.15 CDJ66166.1 - 4.2 7.3 8.1 4.8 7.1 8.1 1.1 1 0 0 1 1 1 0 PXA domain Peptidase_S8 PF00082.22 CDJ66167.1 - 0.009 15.3 7.2 0.012 14.9 7.2 1.2 1 0 0 1 1 1 1 Subtilase family SR-25 PF10500.9 CDJ66167.1 - 0.43 10.2 49.0 1.1 8.8 13.9 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF936 PF06075.12 CDJ66167.1 - 0.94 8.3 28.6 1.2 8.0 28.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SRP-alpha_N PF04086.13 CDJ66167.1 - 0.97 9.3 34.8 1.2 9.0 34.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Mitofilin PF09731.9 CDJ66167.1 - 2.3 6.9 30.9 2.8 6.7 30.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.9 CDJ66167.1 - 2.6 6.5 23.9 3.3 6.1 23.9 1.1 1 0 0 1 1 1 0 Macoilin family Chorion_2 PF03964.15 CDJ66167.1 - 2.8 8.8 44.1 0.08 13.8 14.2 2.7 1 1 1 2 2 2 0 Chorion family 2 SLC12 PF03522.15 CDJ66167.1 - 5.4 5.9 21.1 7.2 5.5 21.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 RAP1 PF07218.11 CDJ66167.1 - 5.7 5.1 11.9 5.9 5.0 11.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ66169.1 - 0.0042 16.7 10.6 0.0042 16.7 10.6 8.2 2 1 4 8 8 8 4 Nuclear RNA-splicing-associated protein zf-C2HC_2 PF13913.6 CDJ66169.1 - 0.015 15.1 5.9 0.039 13.8 5.9 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Presenilin PF01080.17 CDJ66170.1 - 0.057 12.2 5.6 0.071 11.9 5.6 1.2 1 0 0 1 1 1 0 Presenilin DUF2065 PF09838.9 CDJ66170.1 - 0.063 13.3 0.9 0.4 10.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Pex14_N PF04695.13 CDJ66170.1 - 0.12 13.0 18.9 0.15 12.7 3.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EIIBC-GUT_N PF03612.14 CDJ66170.1 - 3.2 7.5 8.4 5.4 6.7 0.1 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus EPL1 PF10513.9 CDJ66170.1 - 3.8 7.9 10.4 6.4 7.1 2.6 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like RskA PF10099.9 CDJ66171.1 - 5e-06 26.9 15.3 0.0028 18.0 8.2 3.3 1 1 1 2 2 2 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ66171.1 - 0.00068 19.3 1.1 0.00068 19.3 1.1 3.1 3 0 0 3 3 3 2 Spt20 family DUF3947 PF13135.6 CDJ66171.1 - 0.012 15.7 1.3 0.012 15.7 1.3 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3947) VIR_N PF15912.5 CDJ66171.1 - 0.22 11.1 3.0 0.49 10.0 1.8 1.9 2 0 0 2 2 2 0 Virilizer, N-terminal Comm PF15957.5 CDJ66171.1 - 3.1 8.2 12.0 0.41 11.0 2.3 3.1 3 0 0 3 3 3 0 Commissureless Pkinase PF00069.25 CDJ66172.1 - 6.4e-45 153.6 4.4 7.3e-18 64.9 3.0 4.9 3 1 1 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ66172.1 - 2.4e-20 72.9 3.0 1.1e-14 54.4 0.1 3.6 3 1 0 3 3 3 3 Protein tyrosine kinase Presenilin PF01080.17 CDJ66172.1 - 6.8e-05 21.8 8.1 6.8e-05 21.8 8.1 3.4 2 1 0 3 3 3 1 Presenilin Pex14_N PF04695.13 CDJ66172.1 - 0.001 19.8 18.3 0.001 19.8 18.3 6.3 3 2 1 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.9 CDJ66172.1 - 0.0015 18.2 1.8 0.0015 18.2 1.8 4.2 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein Ribonuc_P_40 PF08584.11 CDJ66172.1 - 0.014 14.7 0.5 0.014 14.7 0.5 2.7 3 0 0 3 3 3 0 Ribonuclease P 40kDa (Rpp40) subunit O-antigen_lig PF13425.6 CDJ66172.1 - 2.7 6.7 2.8 6.6 5.4 2.8 1.6 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SPX PF03105.19 CDJ66174.1 - 0.018 14.9 4.4 0.02 14.8 4.4 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ66174.1 - 0.13 11.1 5.1 0.14 11.0 5.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ66174.1 - 0.53 9.0 1.1 0.63 8.7 1.1 1.1 1 0 0 1 1 1 0 Presenilin RAP1 PF07218.11 CDJ66174.1 - 0.94 7.7 10.7 1.1 7.5 10.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1180 PF06679.12 CDJ66174.1 - 0.94 9.9 17.0 5.7 7.3 6.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) DUF755 PF05501.11 CDJ66174.1 - 10 6.5 21.4 20 5.5 21.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Spt20 PF12090.8 CDJ66175.1 - 0.54 9.8 7.9 0.81 9.2 7.9 1.3 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ66175.1 - 3.2 6.8 7.1 4.2 6.4 7.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ66175.1 - 4.2 7.3 17.7 5.3 6.9 17.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF73-100_C PF11718.8 CDJ66176.1 - 3.6e-06 26.7 4.9 3.6e-06 26.7 4.9 2.2 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term RskA PF10099.9 CDJ66177.1 - 0.00016 22.0 19.7 0.00039 20.8 7.5 12.9 3 3 8 11 11 11 3 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ66178.1 - 0.0011 18.6 18.7 0.0011 18.6 18.7 2.9 3 0 0 3 3 3 1 Spt20 family DUF2828 PF11443.8 CDJ66178.1 - 0.0026 15.9 6.7 0.0049 15.0 6.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) EOS1 PF12326.8 CDJ66178.1 - 0.021 14.8 0.0 0.45 10.4 0.0 2.5 2 2 0 2 2 2 0 N-glycosylation protein Dimerisation PF08100.11 CDJ66178.1 - 0.16 12.0 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Thg1C PF14413.6 CDJ66178.1 - 0.17 12.0 14.0 0.19 11.9 0.8 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain RAB3GAP2_N PF14655.6 CDJ66178.1 - 0.51 9.5 9.5 0.59 9.3 4.1 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ESM4 PF15952.5 CDJ66178.1 - 0.66 10.4 19.8 0.89 10.0 9.0 3.0 3 0 0 3 3 3 0 Enhancer of split M4 family BAF1_ABF1 PF04684.13 CDJ66178.1 - 0.71 8.9 16.2 0.038 13.1 10.7 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Apt1 PF10351.9 CDJ66178.1 - 2 7.2 19.0 2.4 6.9 4.9 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Peptidase_S49_N PF08496.10 CDJ66178.1 - 2.5 8.1 14.4 1.4 8.9 6.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Het-C PF07217.11 CDJ66178.1 - 3 6.3 12.3 1.1 7.7 0.3 2.1 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C MecA PF05389.12 CDJ66178.1 - 5 6.7 15.6 0.27 10.8 3.5 2.5 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) Rxt3 PF08642.10 CDJ66178.1 - 6.8 7.5 6.8 4.7 8.0 2.7 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Peptidase_U57 PF05582.12 CDJ66178.1 - 7.4 5.7 10.5 22 4.2 5.6 2.1 2 0 0 2 2 2 0 YabG peptidase U57 Fe_bilin_red PF05996.12 CDJ66180.1 - 0.23 11.1 4.3 0.44 10.2 4.3 1.4 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase Spt20 PF12090.8 CDJ66180.1 - 2 8.0 16.3 3.3 7.3 16.3 1.4 1 0 0 1 1 1 0 Spt20 family DUF4667 PF15700.5 CDJ66181.1 - 0.0069 16.5 1.9 0.0069 16.5 1.9 6.5 2 1 2 4 4 4 1 Domain of unknown function (DUF4667) Arch_fla_DE PF04659.13 CDJ66182.1 - 0.027 14.3 0.0 0.068 13.0 0.0 1.6 2 0 0 2 2 2 0 Archaeal flagella protein Histone PF00125.24 CDJ66183.1 - 1.4e-23 83.7 1.2 1.6e-23 83.5 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 CDJ66183.1 - 9.1e-05 23.1 1.3 0.0001 22.9 1.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Histone_H2A_C PF16211.5 CDJ66184.1 - 5.1e-19 67.7 0.3 5.1e-19 67.7 0.3 1.8 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 CDJ66184.1 - 3.2e-15 56.6 0.0 4.2e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDJ66184.1 - 6.8e-05 23.1 0.0 9.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone IL23 PF16649.5 CDJ66186.1 - 0.039 14.0 1.0 0.039 14.0 1.0 1.0 1 0 0 1 1 1 0 Interleukin 23 subunit alpha Ras PF00071.22 CDJ66187.1 - 1.2e-25 90.0 0.0 1.7e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ66187.1 - 8.5e-05 22.8 0.6 0.00018 21.7 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ge1_WD40 PF16529.5 CDJ66188.1 - 0.08 11.9 0.1 0.16 10.9 0.1 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RskA PF10099.9 CDJ66189.1 - 0.00071 19.9 3.7 0.00078 19.8 3.7 1.0 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Adeno_PIX PF03955.14 CDJ66189.1 - 0.008 16.3 1.2 0.0096 16.1 1.2 1.1 1 0 0 1 1 1 1 Adenovirus hexon-associated protein (IX) AAA_23 PF13476.6 CDJ66190.1 - 0.011 16.2 0.2 0.011 16.2 0.2 2.1 2 0 0 2 2 2 0 AAA domain TSSC4 PF15264.6 CDJ66190.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.5 2 1 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 DUF1043 PF06295.12 CDJ66190.1 - 6.5 6.8 22.3 1.2 9.1 5.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Gpi1 PF05024.15 CDJ66191.1 - 2e-27 96.5 5.5 3.3e-27 95.8 5.5 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) SR-25 PF10500.9 CDJ66191.1 - 7 6.2 25.4 0.76 9.3 9.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ66192.1 - 7.8e-06 26.1 61.7 0.0019 18.3 46.9 3.4 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ66192.1 - 5.4e-05 23.4 12.5 0.00025 21.3 10.6 2.4 2 0 0 2 2 2 1 DDHD domain RPOL_N PF14700.6 CDJ66192.1 - 8.7e-05 22.1 17.5 8.7e-05 22.1 17.5 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal SAPS PF04499.15 CDJ66192.1 - 0.0053 15.6 10.8 0.0089 14.9 10.8 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Zip PF02535.22 CDJ66192.1 - 0.015 14.6 2.3 0.033 13.4 2.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter ABC2_membrane_2 PF12679.7 CDJ66192.1 - 0.027 13.7 2.1 0.13 11.5 2.1 2.3 1 0 0 1 1 1 0 ABC-2 family transporter protein GREB1 PF15782.5 CDJ66192.1 - 0.046 10.9 16.0 0.08 10.1 16.0 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SID-1_RNA_chan PF13965.6 CDJ66192.1 - 0.16 10.4 4.7 0.23 9.8 4.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TT_ORF1 PF02956.14 CDJ66192.1 - 0.22 10.1 9.9 0.42 9.2 9.9 1.3 1 0 0 1 1 1 0 TT viral orf 1 TERB2 PF15101.6 CDJ66192.1 - 0.33 11.0 30.5 0.47 10.5 23.4 2.7 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF2151 PF10221.9 CDJ66192.1 - 0.73 8.4 9.6 1.1 7.8 9.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator RR_TM4-6 PF06459.12 CDJ66192.1 - 0.8 9.5 35.2 0.019 14.8 26.9 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ66192.1 - 0.98 9.4 20.5 0.38 10.8 16.4 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.6 CDJ66192.1 - 1.2 9.2 20.7 2.5 8.3 17.9 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.19 CDJ66192.1 - 1.3 6.9 25.1 0.37 8.7 21.7 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Hydin_ADK PF17213.3 CDJ66192.1 - 1.6 9.0 17.8 3.4 7.9 14.6 2.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Tim54 PF11711.8 CDJ66192.1 - 1.9 7.2 21.7 0.098 11.4 15.4 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 CDJ66192.1 - 1.9 7.2 32.9 0.084 11.6 25.4 2.0 2 0 0 2 2 2 0 Presenilin CDC45 PF02724.14 CDJ66192.1 - 2.1 6.6 21.9 1.2 7.3 19.5 1.7 2 0 0 2 2 2 0 CDC45-like protein DUF4045 PF13254.6 CDJ66192.1 - 2.3 7.8 24.0 0.039 13.6 15.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Pkinase_fungal PF17667.1 CDJ66192.1 - 3 6.5 8.3 5.4 5.7 8.3 1.3 1 0 0 1 1 1 0 Fungal protein kinase Endostatin PF06482.11 CDJ66192.1 - 3.2 7.1 22.3 0.39 10.1 16.8 1.9 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Raftlin PF15250.6 CDJ66192.1 - 3.6 6.2 19.8 43 2.7 19.7 2.0 2 0 0 2 2 2 0 Raftlin VIR_N PF15912.5 CDJ66192.1 - 4.8 6.7 13.6 12 5.4 13.6 1.6 1 0 0 1 1 1 0 Virilizer, N-terminal Apt1 PF10351.9 CDJ66192.1 - 5.3 5.8 15.5 0.66 8.8 9.5 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain PAT1 PF09770.9 CDJ66192.1 - 5.5 5.1 46.9 1 7.5 37.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Med19 PF10278.9 CDJ66192.1 - 8.8 6.2 17.7 0.67 9.9 11.7 1.9 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF5427 PF10310.9 CDJ66192.1 - 9.1 5.1 31.5 0.26 10.2 22.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Ureide_permease PF07168.11 CDJ66192.1 - 9.2 4.9 10.9 57 2.3 11.4 2.1 2 0 0 2 2 2 0 Ureide permease GAGA_bind PF06217.12 CDJ66192.1 - 10 6.3 20.2 0.87 9.8 14.6 1.8 2 0 0 2 2 2 0 GAGA binding protein-like family Tic110 PF16940.5 CDJ66193.1 - 3.2 6.1 4.9 4.1 5.8 4.9 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter TGT PF01702.18 CDJ66195.1 - 2e-15 56.8 0.1 1.1e-10 41.2 0.1 2.9 3 1 0 3 3 2 2 Queuine tRNA-ribosyltransferase Zip PF02535.22 CDJ66195.1 - 0.014 14.6 0.9 0.022 14.0 0.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 CDJ66195.1 - 0.053 11.6 11.3 0.07 11.2 11.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.13 CDJ66195.1 - 0.08 11.7 12.5 0.12 11.2 12.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_11 PF13086.6 CDJ66195.1 - 0.099 12.4 14.5 0.16 11.7 14.5 1.2 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 CDJ66195.1 - 0.13 10.6 12.2 0.17 10.2 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein XRN_M PF17846.1 CDJ66195.1 - 0.21 10.5 11.5 0.21 10.5 10.4 1.4 2 0 0 2 2 2 0 Xrn1 helical domain Ndc1_Nup PF09531.10 CDJ66195.1 - 0.28 9.8 8.1 0.5 9.0 8.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF908 PF06012.12 CDJ66195.1 - 0.33 10.3 13.9 0.59 9.5 13.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SLC12 PF03522.15 CDJ66195.1 - 1.1 8.2 16.2 1.6 7.7 16.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 LMBR1 PF04791.16 CDJ66195.1 - 1.5 7.6 2.7 2 7.2 2.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MDM10 PF12519.8 CDJ66195.1 - 1.8 7.4 9.9 2.4 6.9 9.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Dicty_REP PF05086.12 CDJ66195.1 - 3.5 5.5 8.3 4.4 5.2 8.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF913 PF06025.12 CDJ66195.1 - 5.3 5.9 9.3 8.4 5.3 9.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CDJ66195.1 - 6.1 5.5 23.2 10 4.8 23.2 1.3 1 0 0 1 1 1 0 Presenilin CAF1 PF04857.20 CDJ66195.1 - 6.7 5.8 15.5 9.5 5.3 15.5 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Peptidase_S64 PF08192.11 CDJ66195.1 - 9.7 4.5 11.1 13 4.1 11.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 zf-C3HC4_2 PF13923.6 CDJ66196.1 - 0.00056 19.7 0.5 0.0011 18.8 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ66196.1 - 0.0012 18.8 0.3 0.0027 17.7 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ66196.1 - 0.002 17.9 0.3 0.0041 17.0 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ66196.1 - 0.018 14.9 0.2 0.041 13.7 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ66196.1 - 0.059 13.7 0.5 0.14 12.6 0.5 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 CDJ66196.1 - 0.07 12.9 1.1 0.13 12.1 1.1 1.4 1 0 0 1 1 1 0 RING-like zinc finger SRP-alpha_N PF04086.13 CDJ66197.1 - 0.71 9.8 14.9 0.8 9.6 14.9 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Tho2 PF11262.8 CDJ66197.1 - 2.1 7.5 12.7 2.6 7.2 12.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Thioredoxin_11 PF18078.1 CDJ66197.1 - 6.7 6.8 12.6 0.41 10.8 4.2 2.1 1 1 1 2 2 2 0 Thioredoxin-like SNTX domain LCIB_C_CA PF18599.1 CDJ66197.1 - 8.5 5.6 9.8 0.77 9.0 5.3 1.5 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases UCH PF00443.29 CDJ66199.1 - 6e-35 121.0 0.0 8.5e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDJ66199.1 - 1.9e-13 50.5 4.8 3.4e-13 49.7 4.8 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein AF-4 PF05110.13 CDJ66199.1 - 0.0011 17.2 16.5 0.0016 16.7 16.5 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Apt1 PF10351.9 CDJ66199.1 - 0.04 12.8 1.7 0.057 12.3 1.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ66199.1 - 0.24 11.0 24.6 0.41 10.2 24.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.7 CDJ66199.1 - 1.2 8.9 9.9 2.7 7.8 0.2 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Cys_rich_FGFR PF00839.17 CDJ66199.1 - 1.4 9.1 4.2 0.42 10.8 0.4 2.1 3 0 0 3 3 3 0 Cysteine rich repeat MAP65_ASE1 PF03999.12 CDJ66199.1 - 2.3 6.8 5.0 3.8 6.1 5.0 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) CCDC106 PF15794.5 CDJ66199.1 - 4.3 7.0 7.6 7.9 6.1 7.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SPX PF03105.19 CDJ66199.1 - 10 5.9 13.0 15 5.4 13.0 1.2 1 0 0 1 1 1 0 SPX domain Hydrolase_4 PF12146.8 CDJ66200.1 - 9e-05 21.8 0.0 0.035 13.4 0.0 2.6 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peroxin-3 PF04882.12 CDJ66200.1 - 0.053 12.5 11.1 0.59 9.1 0.4 2.1 2 0 0 2 2 2 0 Peroxin-3 SPX PF03105.19 CDJ66200.1 - 0.06 13.3 13.8 0.098 12.6 13.8 1.2 1 0 0 1 1 1 0 SPX domain RCR PF12273.8 CDJ66200.1 - 0.14 12.8 8.6 0.094 13.4 2.9 3.2 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red Neur_chan_memb PF02932.16 CDJ66200.1 - 0.36 10.9 6.5 0.2 11.7 0.7 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CCDC53 PF10152.9 CDJ66200.1 - 1.4 9.3 18.3 0.68 10.3 7.8 3.1 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Med15 PF09606.10 CDJ66200.1 - 2 7.0 45.3 3.4 6.2 45.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF913 PF06025.12 CDJ66200.1 - 2.1 7.2 6.3 20 4.0 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Ctr PF04145.15 CDJ66200.1 - 2.7 8.6 7.1 9.5 6.8 1.4 2.7 2 0 0 2 2 2 0 Ctr copper transporter family RNA_pol_Rpc4 PF05132.14 CDJ66200.1 - 7.8 6.9 15.5 7.9 6.9 0.0 3.1 4 0 0 4 4 4 0 RNA polymerase III RPC4 YABBY PF04690.13 CDJ66200.1 - 8.1 7.0 10.7 26 5.3 4.6 2.4 2 0 0 2 2 2 0 YABBY protein Apt1 PF10351.9 CDJ66200.1 - 8.8 5.1 12.8 1.9 7.2 1.9 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain ORC2 PF04084.14 CDJ66201.1 - 4.1e-36 124.5 0.0 2.2e-20 72.8 0.0 2.3 1 1 1 2 2 2 2 Origin recognition complex subunit 2 IMUP PF15761.5 CDJ66201.1 - 0.86 10.3 17.1 0.52 11.0 3.4 2.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein RskA PF10099.9 CDJ66201.1 - 3.5 7.9 16.0 0.16 12.2 7.4 2.9 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Kinesin_assoc PF16183.5 CDJ66201.1 - 7 6.8 6.4 0.91 9.6 0.5 2.4 3 0 0 3 3 3 0 Kinesin-associated adh_short PF00106.25 CDJ66202.1 - 5.2e-15 55.4 0.4 1.3e-14 54.2 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ66202.1 - 9.7e-14 51.5 0.1 1.3e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ66202.1 - 2e-05 24.6 0.2 7.3e-05 22.7 0.1 1.9 2 0 0 2 2 2 1 KR domain IPPT PF01715.17 CDJ66202.1 - 0.15 11.9 0.0 0.45 10.3 0.0 1.8 2 0 0 2 2 2 0 IPP transferase Kelch_4 PF13418.6 CDJ66203.1 - 1.1e-18 66.9 5.6 0.00011 22.1 0.0 4.5 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ66203.1 - 2.5e-16 59.5 6.2 0.002 18.3 0.0 5.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ66203.1 - 2.1e-15 56.3 8.1 0.0058 16.6 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 CDJ66203.1 - 1.6e-14 53.2 9.2 3e-05 23.5 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CDJ66203.1 - 3.9e-13 49.2 6.1 0.00028 21.1 0.0 4.4 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CDJ66203.1 - 1e-11 44.3 9.3 0.022 14.7 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Yuri_gagarin PF15934.5 CDJ66203.1 - 0.023 14.6 2.7 0.037 13.9 2.7 1.2 1 0 0 1 1 1 0 Yuri gagarin DUF241 PF03087.14 CDJ66203.1 - 0.05 13.4 0.0 0.05 13.4 0.0 1.5 2 0 0 2 2 2 0 Arabidopsis protein of unknown function DUF4678 PF15727.5 CDJ66203.1 - 0.072 12.3 0.2 0.072 12.3 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4678) APG6_N PF17675.1 CDJ66203.1 - 0.19 12.3 8.6 0.041 14.4 4.8 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Prefoldin_2 PF01920.20 CDJ66203.1 - 0.5 10.3 5.7 0.17 11.9 1.3 2.1 2 0 0 2 2 2 0 Prefoldin subunit MRP-L28 PF09812.9 CDJ66203.1 - 5.3 7.1 7.6 3.6 7.7 1.5 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 TFIIS_C PF01096.18 CDJ66204.1 - 1.3e-14 53.8 3.5 1.3e-14 53.8 3.5 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 CDJ66204.1 - 1.7 8.9 18.3 4.6 7.4 0.1 4.4 3 1 0 3 3 3 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 CDJ66204.1 - 6.3 6.6 18.0 0.52 10.0 1.6 4.3 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Exo_endo_phos PF03372.23 CDJ66205.1 - 1.5e-17 63.9 0.1 2.3e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ABC_ATPase PF09818.9 CDJ66207.1 - 5.8e-173 575.8 0.0 7.7e-173 575.4 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 CDJ66207.1 - 0.002 18.7 0.0 0.0027 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ66207.1 - 0.095 12.5 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4578 PF15147.6 CDJ66209.1 - 0.012 16.5 14.0 0.012 16.5 14.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4578) Pertus-S4-tox PF09275.10 CDJ66209.1 - 0.19 12.0 0.9 0.61 10.4 0.0 2.1 1 1 0 2 2 2 0 Pertussis toxin S4 subunit Hamartin PF04388.12 CDJ66209.1 - 1.3 7.6 33.5 1.7 7.2 33.5 1.0 1 0 0 1 1 1 0 Hamartin protein SpoIIP PF07454.11 CDJ66209.1 - 2.3 7.6 30.4 1.1 8.6 10.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) FAM176 PF14851.6 CDJ66209.1 - 5.3 6.7 19.0 1.1 8.9 5.6 2.2 2 0 0 2 2 2 0 FAM176 family Connexin PF00029.19 CDJ66209.1 - 7.5 6.2 21.8 7.5 6.2 8.2 2.1 2 0 0 2 2 2 0 Connexin Paf1 PF03985.13 CDJ66209.1 - 8.4 5.3 28.3 3 6.8 9.9 2.1 2 0 0 2 2 2 0 Paf1 EBP50_C PF09007.11 CDJ66209.1 - 8.8 7.3 36.9 0.46 11.5 15.4 2.2 2 0 0 2 2 2 0 EBP50, C-terminal RPA43_OB PF17875.1 CDJ66209.1 - 9.6 6.9 23.4 1.4 9.5 7.9 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF737 PF05300.11 CDJ66211.1 - 0.071 13.5 6.0 0.09 13.1 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) SPX PF03105.19 CDJ66211.1 - 0.1 12.5 8.7 0.12 12.3 8.7 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ66211.1 - 0.25 10.1 6.2 0.3 9.9 6.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S64 PF08192.11 CDJ66211.1 - 0.4 9.1 3.4 0.4 9.1 3.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 CCDC106 PF15794.5 CDJ66211.1 - 0.57 9.9 8.7 0.82 9.3 8.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Macoilin PF09726.9 CDJ66211.1 - 0.66 8.5 7.4 0.8 8.2 7.4 1.3 1 0 0 1 1 1 0 Macoilin family Corona_nucleoca PF00937.18 CDJ66211.1 - 3.4 6.6 10.4 4.1 6.4 10.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein AF-4 PF05110.13 CDJ66211.1 - 8.9 4.2 21.5 10 4.0 21.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GEN1_C PF18380.1 CDJ66212.1 - 0.018 15.9 2.4 0.027 15.4 2.4 1.3 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain SR-25 PF10500.9 CDJ66213.1 - 0.0014 18.3 35.1 0.0026 17.4 6.1 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ66213.1 - 0.0015 18.8 13.8 0.0015 18.8 13.8 2.5 2 1 0 2 2 2 1 Anti-sigma-K factor rskA ANAPC1 PF12859.7 CDJ66213.1 - 0.42 11.2 7.3 0.13 12.8 0.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Suf PF05843.14 CDJ66213.1 - 2.1 8.3 13.6 0.39 10.7 3.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) IMUP PF15761.5 CDJ66213.1 - 3.1 8.5 36.2 0.21 12.3 17.9 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein Rpr2 PF04032.16 CDJ66214.1 - 0.0031 17.8 35.0 0.0031 17.8 35.0 4.2 2 2 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pex14_N PF04695.13 CDJ66214.1 - 0.023 15.3 15.5 0.023 15.3 15.5 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MecA PF05389.12 CDJ66214.1 - 0.026 14.2 1.9 0.033 13.8 1.9 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) XRN_M PF17846.1 CDJ66214.1 - 0.05 12.6 2.7 0.061 12.3 2.7 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF913 PF06025.12 CDJ66214.1 - 0.27 10.2 9.2 14 4.6 9.2 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) EIIBC-GUT_N PF03612.14 CDJ66214.1 - 0.5 10.1 7.1 1.1 9.0 7.1 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4770 PF15994.5 CDJ66214.1 - 3 8.0 12.4 6.5 7.0 12.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) eIF-3_zeta PF05091.12 CDJ66214.1 - 6.9 5.5 19.7 11 4.9 19.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 CDJ66214.1 - 8.6 5.3 9.2 5.5 5.9 7.1 1.6 2 0 0 2 2 2 0 CLN3 protein DUF2370 PF10176.9 CDJ66214.1 - 10 5.7 7.7 0.72 9.4 2.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Spt20 PF12090.8 CDJ66215.1 - 0.00032 20.4 0.4 0.00038 20.2 0.4 1.2 1 0 0 1 1 1 1 Spt20 family TctB PF07331.11 CDJ66215.1 - 0.0036 17.6 0.2 0.0064 16.8 0.2 1.4 1 1 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family DUF4667 PF15700.5 CDJ66215.1 - 0.0036 17.4 3.0 0.0053 16.9 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ66215.1 - 0.007 16.4 6.2 0.0088 16.1 6.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GRDA PF04723.14 CDJ66215.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A Lin-8 PF03353.15 CDJ66215.1 - 0.15 11.6 1.5 0.22 11.0 1.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sporozoite_P67 PF05642.11 CDJ66215.1 - 0.18 9.9 2.2 0.2 9.7 2.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1645 PF07816.11 CDJ66215.1 - 2 8.9 11.6 0.94 10.0 9.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) DUF3446 PF11928.8 CDJ66215.1 - 2.3 8.6 21.2 0.052 13.8 12.3 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ66215.1 - 3.3 7.2 19.7 0.79 9.3 15.4 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sec63 PF02889.16 CDJ66216.1 - 1.6e-05 24.2 0.0 1.8e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain T4_baseplate PF12322.8 CDJ66216.1 - 0.0053 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 T4 bacteriophage base plate protein AP2 PF00847.20 CDJ66217.1 - 0.0075 16.5 3.4 0.027 14.7 3.4 1.9 1 0 0 1 1 1 1 AP2 domain DUF4477 PF14780.6 CDJ66217.1 - 0.3 10.7 1.2 19 4.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) SUIM_assoc PF16619.5 CDJ66217.1 - 2.4 8.3 0.0 0.1 12.7 0.4 5.5 4 2 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ66217.1 - 4 7.3 34.9 1.1 9.2 27.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MT-A70 PF05063.14 CDJ66218.1 - 1.9e-24 86.5 1.3 2e-11 44.1 0.0 3.6 2 1 1 3 3 3 3 MT-A70 SUIM_assoc PF16619.5 CDJ66218.1 - 0.42 10.7 24.6 0.041 14.0 6.0 3.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ66218.1 - 1.9 8.4 22.2 1.2 9.0 4.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cyclin PF08613.11 CDJ66219.1 - 3.1e-29 102.4 0.0 6e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CDJ66219.1 - 2.8e-11 43.3 0.2 4.1e-11 42.7 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain KH_6 PF15985.5 CDJ66220.1 - 1.4e-10 41.4 0.0 2.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 KH domain Adeno_PIX PF03955.14 CDJ66220.1 - 0.053 13.7 0.9 0.053 13.7 0.9 1.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Methyltransf_16 PF10294.9 CDJ66221.1 - 0.0092 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase DUF2183 PF09949.9 CDJ66222.1 - 0.014 15.7 0.0 0.063 13.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) HECT PF00632.25 CDJ66225.1 - 1.9e-35 122.8 0.0 3.5e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_5 PF13857.6 CDJ66225.1 - 3.8e-08 33.4 0.3 0.084 13.2 0.0 4.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ66225.1 - 8.1e-08 32.8 0.0 1.5e-06 28.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ66225.1 - 1.4e-06 28.5 0.2 0.29 11.7 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 CDJ66225.1 - 3.9e-05 24.1 0.0 0.47 11.1 0.1 4.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ66225.1 - 0.0015 18.9 0.0 1.5 9.7 0.0 3.9 2 0 0 2 2 2 1 Ankyrin repeat Exonuc_VII_L PF02601.15 CDJ66225.1 - 8 5.9 12.3 0.18 11.3 2.5 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Spt20 PF12090.8 CDJ66226.1 - 3 7.4 12.8 0.035 13.7 5.0 1.7 2 0 0 2 2 2 0 Spt20 family DXPR_C PF13288.6 CDJ66227.1 - 4.7e-28 97.8 0.9 1.3e-20 73.8 0.1 2.2 1 1 1 2 2 2 2 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 CDJ66227.1 - 3.2e-10 40.0 0.5 1e-09 38.4 0.1 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXP_reductoisom PF02670.16 CDJ66228.1 - 5.5e-33 114.4 0.1 5.5e-33 114.4 0.1 3.8 4 1 0 4 4 3 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.12 CDJ66228.1 - 7.6e-13 48.4 0.0 2e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Exonuc_VII_L PF02601.15 CDJ66228.1 - 0.0046 16.6 8.7 0.0078 15.8 8.7 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF3675 PF12428.8 CDJ66228.1 - 0.16 12.5 1.6 0.5 10.9 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Rrn6 PF10214.9 CDJ66228.1 - 0.16 10.4 14.4 0.25 9.8 14.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PAT1 PF09770.9 CDJ66228.1 - 0.36 9.1 19.0 0.58 8.4 19.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PMI_typeI PF01238.21 CDJ66228.1 - 0.73 9.0 8.3 1.1 8.4 8.3 1.2 1 0 0 1 1 1 0 Phosphomannose isomerase type I GFO_IDH_MocA PF01408.22 CDJ66228.1 - 0.98 10.3 0.0 0.98 10.3 0.0 3.2 3 2 0 3 3 2 0 Oxidoreductase family, NAD-binding Rossmann fold TFIIA PF03153.13 CDJ66228.1 - 1.9 8.4 37.3 0.012 15.7 25.0 2.6 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Sec62 PF03839.16 CDJ66228.1 - 8.1 5.9 8.5 13 5.2 8.5 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 CDJ66228.1 - 8.3 5.1 8.8 14 4.3 8.8 1.3 1 0 0 1 1 1 0 Presenilin Not1 PF04054.15 CDJ66229.1 - 7.8e-98 327.8 3.2 2.6e-59 201.0 1.5 2.7 3 0 0 3 3 3 2 CCR4-Not complex component, Not1 SUIM_assoc PF16619.5 CDJ66229.1 - 6.4e-05 22.9 42.1 0.00074 19.5 2.8 3.7 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 Dymeclin PF09742.9 CDJ66229.1 - 0.0018 16.8 2.2 0.0018 16.8 2.2 2.0 2 0 0 2 2 2 1 Dyggve-Melchior-Clausen syndrome protein Pex14_N PF04695.13 CDJ66229.1 - 0.0048 17.6 1.7 0.0048 17.6 1.7 4.5 3 2 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.16 CDJ66229.1 - 3.8 7.5 5.9 1.7 8.6 2.7 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RskA PF10099.9 CDJ66230.1 - 0.00029 21.2 13.0 0.00029 21.2 13.0 4.5 1 1 2 3 3 3 1 Anti-sigma-K factor rskA DUF4131 PF13567.6 CDJ66230.1 - 0.0015 18.2 2.1 0.032 13.9 0.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4131) Med19 PF10278.9 CDJ66230.1 - 0.052 13.5 1.0 0.052 13.5 1.0 2.7 3 1 1 4 4 3 0 Mediator of RNA pol II transcription subunit 19 DcuA_DcuB PF03605.14 CDJ66230.1 - 0.076 11.9 6.2 0.015 14.2 2.5 1.6 1 1 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF2572 PF10833.8 CDJ66230.1 - 0.08 12.7 9.5 0.48 10.1 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2572) CD20 PF04103.15 CDJ66230.1 - 0.092 12.8 11.2 0.053 13.6 2.4 3.1 2 1 1 3 3 3 0 CD20-like family DUF4179 PF13786.6 CDJ66230.1 - 0.13 12.7 9.0 23 5.6 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) Folate_carrier PF01770.18 CDJ66230.1 - 0.47 9.1 6.0 0.22 10.2 0.6 2.2 2 0 0 2 2 2 0 Reduced folate carrier Bap31 PF05529.12 CDJ66230.1 - 0.54 10.1 2.2 0.75 9.7 0.5 2.1 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region FA_hydroxylase PF04116.13 CDJ66230.1 - 0.69 10.3 15.7 1.3 9.4 15.7 1.4 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily FHIPEP PF00771.20 CDJ66230.1 - 0.82 8.1 10.9 0.24 9.8 0.7 2.2 2 0 0 2 2 2 0 FHIPEP family SID-1_RNA_chan PF13965.6 CDJ66230.1 - 1.8 6.9 5.8 0.49 8.8 1.2 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 CDC27 PF09507.10 CDJ66231.1 - 0.48 9.8 3.2 0.57 9.5 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.13 CDJ66231.1 - 4.5 7.2 7.8 4.7 7.1 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LZ_Tnp_IS66 PF13007.7 CDJ66231.1 - 8 7.3 12.8 18 6.2 10.8 2.4 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain DNA_pol_B_exo1 PF03104.19 CDJ66234.1 - 1.6e-38 132.8 0.0 2.2e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 CDJ66234.1 - 6.7e-05 22.7 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CDJ66234.1 - 0.0001 22.4 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 RNase_H superfamily SR-25 PF10500.9 CDJ66234.1 - 0.00035 20.3 5.6 0.00035 20.3 5.6 3.3 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2057 PF09829.9 CDJ66234.1 - 1.6 8.9 6.7 14 5.8 6.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Methyltransf_34 PF11312.8 CDJ66234.1 - 2.7 7.2 7.4 7.4 5.7 7.3 1.7 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase Spt20 PF12090.8 CDJ66236.1 - 0.099 12.2 21.6 0.097 12.3 21.6 1.0 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ66236.1 - 0.16 10.9 18.1 0.16 10.9 18.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CPSF100_C PF13299.6 CDJ66236.1 - 0.27 11.4 8.7 0.28 11.3 8.7 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4834 PF16118.5 CDJ66236.1 - 0.7 10.9 6.1 0.69 10.9 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pex14_N PF04695.13 CDJ66236.1 - 0.87 10.2 16.8 0.96 10.1 16.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ66236.1 - 1.1 9.2 20.7 1.1 9.2 20.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3464 PF11947.8 CDJ66236.1 - 1.1 9.0 8.6 1 9.1 8.6 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Coilin_N PF15862.5 CDJ66236.1 - 1.3 8.8 9.9 1.6 8.6 9.9 1.1 1 0 0 1 1 1 0 Coilin N-terminus TERB2 PF15101.6 CDJ66236.1 - 1.9 8.5 9.6 1.8 8.5 9.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Kei1 PF08552.11 CDJ66236.1 - 2.4 8.0 6.1 2.6 7.9 6.1 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Presenilin PF01080.17 CDJ66236.1 - 2.5 6.8 7.1 2.4 6.9 7.1 1.0 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CDJ66236.1 - 2.5 8.0 12.2 2.3 8.1 12.2 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0560 PF10577.9 CDJ66236.1 - 2.7 6.4 11.2 2.7 6.4 11.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3391 PF11871.8 CDJ66236.1 - 3.5 8.2 11.2 4.1 8.0 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Androgen_recep PF02166.16 CDJ66236.1 - 4.5 6.0 23.1 4.4 6.0 23.1 1.1 1 0 0 1 1 1 0 Androgen receptor DUF2367 PF10164.9 CDJ66236.1 - 9.2 6.8 7.2 11 6.6 7.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Bac_GDH PF05088.12 CDJ66237.1 - 1.5e-06 26.1 0.0 1.5e-06 26.1 0.0 1.5 2 0 0 2 2 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 CDJ66237.1 - 0.00052 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF2722 PF10846.8 CDJ66237.1 - 0.0013 17.8 13.0 0.0017 17.4 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ66237.1 - 0.0051 16.9 13.0 0.006 16.6 13.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ66237.1 - 0.01 14.6 13.5 0.011 14.5 13.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4770 PF15994.5 CDJ66237.1 - 0.27 11.5 9.2 0.4 10.9 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Peptidase_U57 PF05582.12 CDJ66237.1 - 0.35 10.1 5.5 0.72 9.1 5.5 1.5 1 0 0 1 1 1 0 YabG peptidase U57 Ribosomal_60s PF00428.19 CDJ66237.1 - 0.45 11.1 4.7 0.4 11.3 2.8 1.9 2 0 0 2 2 1 0 60s Acidic ribosomal protein PRC2_HTH_1 PF18118.1 CDJ66237.1 - 0.77 10.6 3.8 0.62 10.9 2.2 1.7 2 0 0 2 2 1 0 Polycomb repressive complex 2 tri-helical domain Presenilin PF01080.17 CDJ66237.1 - 0.79 8.4 4.9 1 8.1 4.9 1.2 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ66237.1 - 0.88 10.2 9.7 4.6 7.9 10.7 1.7 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EIIBC-GUT_N PF03612.14 CDJ66237.1 - 4.4 7.0 6.4 6.8 6.4 6.4 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RTP1_C1 PF10363.9 CDJ66239.1 - 0.027 14.6 0.6 0.11 12.7 0.2 2.1 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 RICTOR_N PF14664.6 CDJ66239.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term RTTN_N PF14726.6 CDJ66239.1 - 0.14 13.0 0.7 9 7.2 0.2 2.2 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning FAM176 PF14851.6 CDJ66240.1 - 0.082 12.6 1.6 0.086 12.5 0.9 1.4 1 1 0 1 1 1 0 FAM176 family IQ PF00612.27 CDJ66241.1 - 2.7e-05 23.6 31.6 0.0099 15.6 1.2 4.5 4 0 0 4 4 4 3 IQ calmodulin-binding motif Feld-I_B PF09252.10 CDJ66241.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Allergen Fel d I-B chain DUF2339 PF10101.9 CDJ66241.1 - 0.48 8.9 25.7 0.63 8.6 25.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) CobS PF02654.15 CDJ66241.1 - 8.2 6.6 11.9 12 6.1 11.9 1.2 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase ketoacyl-synt PF00109.26 CDJ66243.1 - 5.6e-109 363.6 5.0 3.9e-65 219.9 0.0 2.6 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CDJ66243.1 - 6.5e-59 197.1 2.0 6.7e-37 126.1 0.2 3.0 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 CDJ66243.1 - 1.4e-50 171.7 0.0 3.7e-50 170.3 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 CDJ66243.1 - 1.2e-40 140.0 1.6 3e-40 138.7 1.6 1.7 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 CDJ66243.1 - 4.6e-33 114.7 0.0 1.1e-32 113.5 0.0 1.6 1 1 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 CDJ66243.1 - 6.9e-13 48.7 0.4 1.5e-12 47.7 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 CDJ66243.1 - 4.8e-07 29.4 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 CDJ66243.1 - 0.00035 21.0 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension DUF4426 PF14467.6 CDJ66243.1 - 0.0071 16.3 0.0 6.9 6.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4426) Thiolase_N PF00108.23 CDJ66243.1 - 0.012 14.9 2.7 0.17 11.2 0.3 2.4 2 0 0 2 2 2 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 CDJ66243.1 - 0.068 13.0 4.5 0.2 11.5 0.3 3.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sin_N PF04801.13 CDJ66244.1 - 0.022 14.0 11.2 0.027 13.7 11.2 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region SOBP PF15279.6 CDJ66244.1 - 0.1 13.2 19.5 0.15 12.7 19.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4228 PF14009.6 CDJ66244.1 - 0.68 10.3 8.4 1 9.7 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) PAT1 PF09770.9 CDJ66244.1 - 2.4 6.3 19.1 2.8 6.1 19.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SARAF PF06682.12 CDJ66244.1 - 4.7 6.8 14.2 8.4 5.9 14.2 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Lin-8 PF03353.15 CDJ66244.1 - 5.2 6.5 11.9 6.9 6.1 11.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ndc1_Nup PF09531.10 CDJ66244.1 - 6 5.4 7.9 6.7 5.3 7.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ66244.1 - 8.4 5.0 10.1 12 4.6 10.1 1.1 1 0 0 1 1 1 0 Presenilin Secretin_N_2 PF07655.13 CDJ66245.1 - 0.026 15.1 9.0 0.05 14.2 9.0 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain LZ_Tnp_IS66 PF13007.7 CDJ66245.1 - 0.09 13.6 1.5 0.09 13.6 1.5 5.3 3 2 0 3 3 3 0 Transposase C of IS166 homeodomain AF-4 PF05110.13 CDJ66245.1 - 0.67 8.0 38.9 0.13 10.3 34.2 1.8 1 1 1 2 2 2 0 AF-4 proto-oncoprotein DUF755 PF05501.11 CDJ66245.1 - 1.5 9.1 26.7 0.076 13.3 20.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SBE2 PF17076.5 CDJ66245.1 - 6.3 4.9 11.5 6.5 4.8 11.5 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation TFIIA PF03153.13 CDJ66247.1 - 0.071 13.1 10.4 0.083 12.9 10.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAAX_1 PF15895.5 CDJ66247.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 CAAX box cerebral protein 1 DUF755 PF05501.11 CDJ66248.1 - 0.0002 21.6 13.1 0.00029 21.1 13.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) DUF2722 PF10846.8 CDJ66248.1 - 0.00023 20.2 4.6 0.00027 20.0 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TAF4 PF05236.14 CDJ66248.1 - 0.0056 16.5 1.0 0.0064 16.3 1.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Spt20 PF12090.8 CDJ66248.1 - 0.014 15.1 10.3 0.016 14.8 10.3 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ66248.1 - 0.014 15.4 6.2 0.014 15.4 6.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 CDJ66248.1 - 0.019 13.9 8.8 0.021 13.7 8.8 1.2 1 0 0 1 1 1 0 Androgen receptor Lin-8 PF03353.15 CDJ66248.1 - 0.043 13.4 3.4 0.052 13.1 3.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 CDJ66248.1 - 0.11 9.7 2.7 0.11 9.6 2.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RT_RNaseH_2 PF17919.1 CDJ66249.1 - 2.3e-14 53.2 0.0 4.3e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ66249.1 - 2.1e-05 24.7 0.0 5.7e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ66249.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GT87 PF09594.10 CDJ66251.1 - 3.2 7.4 18.4 4.6 6.9 2.1 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 87 Pep3_Vps18 PF05131.14 CDJ66253.1 - 1e-13 51.3 0.0 2.6e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 CDJ66253.1 - 3.1e-05 24.4 2.5 7.7e-05 23.1 2.5 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 CDJ66253.1 - 0.0059 16.5 0.0 0.03 14.2 0.0 2.3 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 CDJ66253.1 - 0.016 15.2 4.7 0.036 14.1 4.7 1.7 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 CDJ66253.1 - 0.09 12.4 6.5 0.27 10.9 6.5 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SPX PF03105.19 CDJ66253.1 - 4.9 7.0 10.2 0.31 10.9 2.1 2.6 3 0 0 3 3 3 0 SPX domain BNIP3 PF06553.12 CDJ66255.1 - 0.0013 18.5 4.5 0.0018 18.0 4.5 1.2 1 0 0 1 1 1 1 BNIP3 CNDH2_C PF16858.5 CDJ66255.1 - 0.014 15.2 2.5 0.019 14.8 2.5 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BUD22 PF09073.10 CDJ66255.1 - 0.015 14.7 8.6 0.018 14.4 8.6 1.1 1 0 0 1 1 1 0 BUD22 WD40 PF00400.32 CDJ66255.1 - 0.024 15.5 0.2 0.089 13.7 0.0 2.1 2 0 0 2 2 1 0 WD domain, G-beta repeat Afi1 PF07792.12 CDJ66255.1 - 0.1 13.1 3.1 0.16 12.4 3.1 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2292 PF10055.9 CDJ66255.1 - 0.12 12.0 0.0 27 4.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) PPL5 PF18168.1 CDJ66255.1 - 0.22 10.8 2.5 0.31 10.3 2.5 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF4746 PF15928.5 CDJ66255.1 - 0.23 10.9 3.9 0.32 10.4 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PPP4R2 PF09184.11 CDJ66255.1 - 1.3 8.5 8.7 1.8 8.1 8.7 1.1 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 CDJ66255.1 - 1.3 7.7 5.0 1.7 7.3 5.0 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CDJ66255.1 - 1.6 7.5 5.5 2 7.1 5.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dendrin PF15498.6 CDJ66255.1 - 1.6 7.4 7.3 2.3 6.8 7.3 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin UPF0560 PF10577.9 CDJ66255.1 - 2.5 6.5 7.8 3.4 6.0 7.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2431 PF10354.9 CDJ66257.1 - 0.0029 17.9 0.0 0.003 17.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PP_kinase_C_1 PF17941.1 CDJ66257.1 - 0.0046 16.5 0.0 0.0057 16.2 0.0 1.1 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain 1 Peptidase_C48 PF02902.19 CDJ66258.1 - 3e-23 82.8 0.0 8.4e-23 81.3 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF2722 PF10846.8 CDJ66258.1 - 0.0017 17.4 3.0 0.0017 17.4 3.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ66258.1 - 0.083 12.5 64.1 0.086 12.4 10.7 3.3 3 0 0 3 3 3 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ66258.1 - 4.9 6.0 69.0 0.14 11.1 14.7 3.4 3 0 0 3 3 3 0 Transcriptional activator LAG-3 RskA PF10099.9 CDJ66259.1 - 4.1e-06 27.2 29.2 0.0006 20.2 22.5 2.6 2 1 1 3 3 3 2 Anti-sigma-K factor rskA DUF4207 PF13904.6 CDJ66259.1 - 0.0031 17.2 5.0 0.0031 17.2 5.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) DUF1793 PF08760.11 CDJ66259.1 - 0.0094 16.4 0.2 0.019 15.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) SPX PF03105.19 CDJ66259.1 - 0.025 14.5 14.1 0.037 14.0 14.1 1.3 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ66259.1 - 0.14 11.0 10.9 0.22 10.3 10.9 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain VitD-bind_III PF09164.10 CDJ66259.1 - 0.32 11.0 0.1 0.32 11.0 0.1 3.5 4 0 0 4 4 4 0 Vitamin D binding protein, domain III PAT1 PF09770.9 CDJ66259.1 - 2 6.6 13.3 2.5 6.3 13.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.11 CDJ66259.1 - 4.2 5.8 14.6 5.6 5.3 14.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.13 CDJ66259.1 - 5 7.0 38.4 5.6 6.9 37.3 1.6 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Dehydrin PF00257.19 CDJ66261.1 - 0.017 15.7 0.2 0.017 15.7 0.2 13.6 7 3 2 9 9 9 0 Dehydrin SARAF PF06682.12 CDJ66262.1 - 0.00026 20.8 12.8 0.00026 20.8 12.8 4.0 4 1 0 4 4 4 2 SOCE-associated regulatory factor of calcium homoeostasis BRCA2 PF00634.18 CDJ66263.1 - 1.5e-23 82.1 0.4 0.00083 19.0 0.0 6.5 6 0 0 6 6 6 6 BRCA2 repeat KH_1 PF00013.29 CDJ66264.1 - 3.5e-09 36.3 0.3 1.7e-06 27.8 0.8 3.5 3 1 0 3 3 3 1 KH domain SUIM_assoc PF16619.5 CDJ66264.1 - 0.74 9.9 23.5 0.062 13.4 2.7 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Surface_antigen PF11054.8 CDJ66267.1 - 5.4e-72 242.4 2.9 6.9e-72 242.0 2.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF3439 PF11921.8 CDJ66267.1 - 0.021 14.8 2.4 0.024 14.6 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Surface_antigen PF11054.8 CDJ66268.1 - 6.4e-78 261.8 2.3 7.7e-78 261.5 2.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen zinc_ribbon_10 PF10058.9 CDJ66268.1 - 0.17 11.6 0.0 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Peptidase_U57 PF05582.12 CDJ66269.1 - 0.019 14.2 3.5 0.045 13.0 3.5 1.6 1 0 0 1 1 1 0 YabG peptidase U57 PIN PF01850.21 CDJ66269.1 - 0.035 14.6 0.1 0.17 12.4 0.1 2.3 1 0 0 1 1 1 0 PIN domain Adaptin_binding PF10199.9 CDJ66269.1 - 0.22 12.1 12.6 0.025 15.2 6.7 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF2722 PF10846.8 CDJ66269.1 - 0.57 9.1 9.8 0.9 8.4 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NapB PF03892.14 CDJ66269.1 - 0.62 10.1 0.0 0.62 10.1 0.0 2.6 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) Roughex PF06020.11 CDJ66269.1 - 3.2 6.8 8.1 6.2 5.8 8.1 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Folliculin PF11704.8 CDJ66269.1 - 3.8 7.3 8.2 2.6 7.9 5.7 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Ribosomal_60s PF00428.19 CDJ66269.1 - 3.9 8.1 18.2 1.1 9.9 11.6 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein PAF-AH_p_II PF03403.13 CDJ66269.1 - 5.7 5.3 9.5 9.1 4.7 9.5 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Alb1 PF09135.11 CDJ66269.1 - 6.4 7.7 10.9 1.2 10.0 5.5 2.3 2 0 0 2 2 2 0 Alb1 DUF5421 PF17458.2 CDJ66269.1 - 8.5 5.7 14.9 12 5.1 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5421) NucS PF01939.16 CDJ66270.1 - 0.22 10.8 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Endonuclease NucS Ribosomal_60s PF00428.19 CDJ66270.1 - 0.25 11.9 9.7 0.15 12.7 6.0 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ66270.1 - 1.1 9.6 9.4 1.5 9.1 9.4 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Metal_resist PF13801.6 CDJ66271.1 - 0.0031 17.7 2.4 0.0031 17.7 2.4 2.7 3 0 0 3 3 3 1 Heavy-metal resistance Spt20 PF12090.8 CDJ66271.1 - 0.69 9.5 6.8 2.4 7.7 7.5 1.4 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ66272.1 - 0.0019 17.8 24.8 0.0027 17.3 24.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Hid1 PF12722.7 CDJ66272.1 - 0.65 8.1 18.0 0.61 8.1 18.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.13 CDJ66272.1 - 0.92 9.4 36.3 1.3 9.0 36.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mucin PF01456.17 CDJ66272.1 - 0.94 9.5 11.3 1.3 9.0 11.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein CDC27 PF09507.10 CDJ66272.1 - 1.1 8.5 25.1 1.3 8.3 25.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 CDJ66272.1 - 1.3 8.8 16.8 1.9 8.3 16.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Menin PF05053.13 CDJ66272.1 - 2.4 6.4 15.9 2.7 6.3 15.9 1.1 1 0 0 1 1 1 0 Menin MTBP_C PF14920.6 CDJ66272.1 - 2.7 7.7 22.4 3.7 7.2 22.4 1.1 1 0 0 1 1 1 0 MDM2-binding SPX PF03105.19 CDJ66272.1 - 3.2 7.6 23.3 3.6 7.4 23.3 1.1 1 0 0 1 1 1 0 SPX domain DTHCT PF08070.11 CDJ66272.1 - 3.3 8.5 14.3 2.4 8.9 12.9 1.5 1 1 0 1 1 1 0 DTHCT (NUC029) region Hydin_ADK PF17213.3 CDJ66272.1 - 5.8 7.1 25.8 7.5 6.8 25.8 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain IMUP PF15761.5 CDJ66272.1 - 7.9 7.2 28.9 1.8 9.3 14.7 2.3 1 1 1 2 2 2 0 Immortalisation up-regulated protein DUF5427 PF10310.9 CDJ66272.1 - 8.7 5.2 24.6 10 5.0 24.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) GATase PF00117.28 CDJ66273.1 - 6e-50 169.7 0.0 8.4e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CDJ66273.1 - 4e-05 23.5 0.1 4e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Peptidase C26 SHR3_chaperone PF08229.11 CDJ66273.1 - 6.2 5.7 4.9 10 5.0 4.9 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 GDA1_CD39 PF01150.17 CDJ66274.1 - 6.6e-12 44.8 0.0 5.5e-11 41.8 0.0 2.3 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family VIR_N PF15912.5 CDJ66274.1 - 8.1 5.9 11.1 19 4.8 11.1 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal Band_3_cyto PF07565.13 CDJ66274.1 - 9.6 5.9 7.9 2.9 7.6 3.5 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CRAL_TRIO PF00650.20 CDJ66275.1 - 1.2e-11 44.6 0.0 1.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Spt20 PF12090.8 CDJ66275.1 - 0.001 18.7 20.7 0.0016 18.1 20.7 1.2 1 0 0 1 1 1 1 Spt20 family Presenilin PF01080.17 CDJ66275.1 - 0.1 11.3 1.0 0.13 11.0 1.0 1.2 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 CDJ66275.1 - 0.14 11.0 0.3 0.2 10.5 0.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ndc1_Nup PF09531.10 CDJ66275.1 - 0.19 10.3 1.0 0.23 10.1 1.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2076 PF09849.9 CDJ66275.1 - 0.41 10.7 18.5 0.58 10.1 18.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CCDC53 PF10152.9 CDJ66275.1 - 1.1 9.7 10.4 1.7 9.0 10.4 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Pex14_N PF04695.13 CDJ66275.1 - 1.2 9.8 16.8 1.8 9.2 16.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ66275.1 - 2.2 8.2 22.0 3 7.7 22.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ66275.1 - 3.6 7.5 11.6 5.4 6.9 11.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 CDJ66275.1 - 5.6 5.1 14.1 7.3 4.7 14.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Amnionless PF14828.6 CDJ66276.1 - 0.009 14.9 0.0 0.1 11.4 0.0 1.9 1 1 1 2 2 2 1 Amnionless Zip PF02535.22 CDJ66276.1 - 0.018 14.3 2.7 0.028 13.7 2.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1206 PF06724.11 CDJ66276.1 - 0.044 13.9 2.6 0.12 12.4 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) ABC_membrane PF00664.23 CDJ66276.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region SOG2 PF10428.9 CDJ66276.1 - 0.31 10.2 4.4 0.4 9.8 4.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 CDJ66276.1 - 0.55 8.7 9.7 0.73 8.3 9.7 1.1 1 0 0 1 1 1 0 Macoilin family SelP_N PF04592.14 CDJ66276.1 - 1.6 8.1 19.0 2.2 7.6 19.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SNF2_N PF00176.23 CDJ66278.1 - 2.2e-41 141.7 0.0 2.8e-32 111.8 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ66278.1 - 1.8e-17 63.7 0.0 4e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ66278.1 - 7.4e-08 32.6 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ66278.1 - 0.00017 21.4 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CDJ66278.1 - 0.0019 17.5 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PNTB PF02233.16 CDJ66280.1 - 4.6e-152 507.1 20.8 3.3e-129 431.8 6.8 2.6 2 1 1 3 3 3 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 CDJ66280.1 - 4.2e-66 222.3 0.3 6.9e-66 221.6 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CDJ66280.1 - 5.1e-18 65.7 0.0 1.2e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 CDJ66280.1 - 3e-11 43.6 5.9 3e-11 43.6 5.9 3.5 3 0 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 CDJ66280.1 - 7.9e-06 25.3 0.1 0.059 12.7 0.2 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 CDJ66280.1 - 0.0062 16.3 0.5 0.12 12.2 0.1 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Tti2 PF10521.9 CDJ66281.1 - 0.00025 20.7 0.3 0.031 13.8 0.0 2.6 2 0 0 2 2 2 2 Tti2 family Med3 PF11593.8 CDJ66281.1 - 0.071 12.3 1.1 0.16 11.1 1.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_11 PF13086.6 CDJ66282.1 - 3e-56 191.1 1.2 7.2e-29 101.4 0.9 3.8 2 1 1 3 3 3 2 AAA domain AAA_12 PF13087.6 CDJ66282.1 - 5.9e-56 189.2 0.0 1.2e-55 188.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ66282.1 - 4e-11 43.0 0.1 0.00012 21.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ66282.1 - 2.6e-10 40.8 0.0 0.0013 19.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CDJ66282.1 - 0.001 18.9 0.3 0.11 12.2 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CDJ66282.1 - 0.023 14.2 0.0 2 7.9 0.0 2.7 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 CDJ66282.1 - 0.07 13.5 0.2 0.63 10.4 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CDJ66282.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP-alpha_N PF04086.13 CDJ66285.1 - 8 6.3 7.7 9.7 6.0 7.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TAL_FSA PF00923.19 CDJ66286.1 - 1.9e-09 37.3 0.7 1.9e-09 37.3 0.7 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF615 PF04751.14 CDJ66286.1 - 0.0027 17.7 1.1 0.0028 17.7 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF615) DUF1084 PF06454.11 CDJ66289.1 - 3.8e-10 39.6 3.9 5.8e-10 39.0 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) MgtE PF01769.16 CDJ66290.1 - 0.26 11.7 1.0 0.53 10.7 1.0 1.4 1 0 0 1 1 1 0 Divalent cation transporter HsbA PF12296.8 CDJ66291.1 - 0.18 12.2 1.1 2.6 8.5 0.2 2.5 2 0 0 2 2 2 0 Hydrophobic surface binding protein A DUF4407 PF14362.6 CDJ66291.1 - 1.2 8.5 30.3 0.72 9.2 12.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DIL PF01843.19 CDJ66291.1 - 2.2 8.6 6.9 0.94 9.8 0.1 3.0 3 1 0 3 3 3 0 DIL domain Nitrate_red_del PF02613.15 CDJ66291.1 - 3.7 7.6 13.0 0.28 11.2 2.5 3.4 1 1 0 2 2 2 0 Nitrate reductase delta subunit Methyltr_RsmB-F PF01189.17 CDJ66292.1 - 6.9e-27 94.4 0.0 2.1e-18 66.7 0.0 2.2 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CDJ66292.1 - 0.0017 18.5 0.0 0.0057 16.8 0.0 1.8 1 1 1 2 2 2 1 FtsJ-like methyltransferase R3H-assoc PF13902.6 CDJ66293.1 - 0.08 13.3 0.8 0.25 11.7 0.0 2.3 2 0 0 2 2 2 0 R3H-associated N-terminal domain DUF4351 PF14261.6 CDJ66294.1 - 0.045 13.8 0.3 0.11 12.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) IBN_N PF03810.19 CDJ66296.1 - 6.3e-06 26.0 1.0 3.1e-05 23.8 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Peptidase_M99_m PF17130.4 CDJ66296.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 RPN6_N PF18055.1 CDJ66296.1 - 0.092 13.1 0.1 0.46 10.9 0.1 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain Hyr1 PF15789.5 CDJ66296.1 - 0.17 11.5 0.8 7.3 6.2 0.2 2.5 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 Pex2_Pex12 PF04757.14 CDJ66297.1 - 1.1e-15 57.8 0.0 9.2e-15 54.8 0.0 2.4 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CDJ66297.1 - 0.00014 21.6 2.6 0.0003 20.6 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SPX PF03105.19 CDJ66297.1 - 0.021 14.8 0.8 0.26 11.2 0.8 2.1 1 1 0 1 1 1 0 SPX domain zf-RING_2 PF13639.6 CDJ66297.1 - 0.024 15.0 5.2 0.052 13.9 5.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ66297.1 - 0.027 14.3 4.0 0.055 13.3 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ66297.1 - 2.4 8.4 6.2 6.3 7.0 6.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING gag_pre-integrs PF13976.6 CDJ66297.1 - 7.7 6.5 6.6 0.88 9.5 0.1 2.8 3 0 0 3 3 3 0 GAG-pre-integrase domain Sybindin PF04099.12 CDJ66298.1 - 5.9e-18 65.2 0.0 7.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family ABC1 PF03109.16 CDJ66300.1 - 2.1e-29 102.1 0.0 3.7e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family DUF3682 PF12446.8 CDJ66300.1 - 0.0047 17.4 5.3 0.0047 17.4 5.3 9.9 8 3 2 10 10 10 1 Protein of unknown function (DUF3682) Pkinase PF00069.25 CDJ66300.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain MORN PF02493.20 CDJ66301.1 - 1.4e-20 71.9 14.6 8.2e-07 28.6 0.4 3.3 3 0 0 3 3 3 3 MORN repeat PMR5N PF14416.6 CDJ66301.1 - 1.8 9.0 5.4 31 5.0 0.1 3.7 4 0 0 4 4 4 0 PMR5 N terminal Domain Lebercilin PF15619.6 CDJ66302.1 - 0.0016 18.2 0.2 0.0018 18.0 0.2 1.0 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease ApoLp-III PF07464.11 CDJ66302.1 - 0.0094 16.0 1.2 0.011 15.8 1.2 1.1 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) InPase PF18823.1 CDJ66302.1 - 0.025 14.3 0.1 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 Inorganic Pyrophosphatase PP2C_C PF07830.13 CDJ66302.1 - 0.071 13.6 0.3 0.079 13.4 0.3 1.1 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain BAF1_ABF1 PF04684.13 CDJ66304.1 - 1.3 8.0 20.7 1.5 7.8 20.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HSD3 PF15244.6 CDJ66304.1 - 8.1 5.8 21.7 9.5 5.6 21.7 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 ComFB PF10719.9 CDJ66305.1 - 0.09 12.9 0.5 0.09 12.9 0.5 3.8 3 2 0 3 3 3 0 Late competence development protein ComFB DUF4179 PF13786.6 CDJ66305.1 - 9.9 6.7 16.9 78 3.8 8.0 4.9 3 2 0 3 3 3 0 Domain of unknown function (DUF4179) BAF1_ABF1 PF04684.13 CDJ66306.1 - 0.79 8.7 19.8 1.3 8.0 19.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UPF1_Zn_bind PF09416.10 CDJ66307.1 - 5.6e-18 65.4 0.0 6.1e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) SUIM_assoc PF16619.5 CDJ66308.1 - 0.23 11.6 32.3 0.19 11.8 3.4 4.1 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ66308.1 - 4.1 7.0 20.9 3 7.4 6.1 3.4 3 0 0 3 3 3 0 Spt20 family zf-UBR PF02207.20 CDJ66309.1 - 9.7e-10 38.5 5.6 2.5e-09 37.1 5.6 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) GRP PF07172.11 CDJ66309.1 - 1.2 9.8 9.7 1.4 9.7 0.3 2.9 2 0 0 2 2 2 0 Glycine rich protein family DUF1645 PF07816.11 CDJ66309.1 - 9.1 6.8 22.9 0.43 11.1 1.6 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1645) Pkinase PF00069.25 CDJ66310.1 - 1e-05 25.1 0.0 1e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain CAF1 PF04857.20 CDJ66312.1 - 0.0033 16.6 0.0 0.0035 16.6 0.0 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease ThiF PF00899.21 CDJ66313.1 - 2.5e-18 66.3 0.0 3.4e-13 49.5 0.0 3.3 1 1 1 2 2 2 2 ThiF family DUF3110 PF11360.8 CDJ66313.1 - 0.0089 16.2 0.1 0.021 15.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) IMUP PF15761.5 CDJ66313.1 - 0.027 15.1 6.6 0.027 15.1 6.6 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF3446 PF11928.8 CDJ66313.1 - 1.8 9.0 20.0 0.38 11.1 12.1 3.2 3 0 0 3 3 3 0 Early growth response N-terminal domain DUF508 PF04370.12 CDJ66313.1 - 2.6 7.8 6.7 4.8 6.9 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) MCM_N PF14551.6 CDJ66314.1 - 1.6e-05 25.4 0.4 3e-05 24.5 0.4 1.5 1 1 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 CDJ66314.1 - 0.0071 16.7 11.6 0.0071 16.7 11.6 1.7 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 Mersacidin PF16934.5 CDJ66314.1 - 0.89 9.4 7.7 1.6 8.6 7.7 1.3 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) SR-25 PF10500.9 CDJ66315.1 - 0.0024 17.5 19.9 0.0024 17.5 19.9 2.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ66315.1 - 0.1 10.7 49.7 0.12 10.4 49.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CCSAP PF15748.5 CDJ66315.1 - 0.57 10.3 46.6 0.75 9.9 46.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RAP1 PF07218.11 CDJ66315.1 - 0.84 7.8 2.4 0.77 8.0 2.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.9 CDJ66315.1 - 8 4.6 54.4 9 4.4 54.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2992 PF11208.8 CDJ66316.1 - 0.041 14.1 20.5 0.047 13.9 20.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) RskA PF10099.9 CDJ66316.1 - 0.2 11.9 13.5 0.28 11.5 13.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF5320 PF17253.2 CDJ66316.1 - 0.38 11.8 5.9 0.51 11.4 5.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Serinc PF03348.15 CDJ66316.1 - 2 7.2 3.6 1.9 7.3 3.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.13 CDJ66316.1 - 2.1 8.3 21.0 2.1 8.2 21.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ66316.1 - 3.1 6.5 11.0 3.1 6.5 11.0 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ66316.1 - 9.4 6.2 6.9 9.4 6.2 6.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3984 PF13136.6 CDJ66316.1 - 9.5 5.5 18.0 12 5.1 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) MNE1 PF13762.6 CDJ66317.1 - 0.26 11.2 3.6 0.89 9.5 3.6 1.8 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component Pkinase PF00069.25 CDJ66318.1 - 9e-36 123.6 0.0 9e-36 123.6 0.0 3.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ66318.1 - 7.2e-25 87.7 3.9 7.4e-24 84.4 0.0 4.0 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ66319.1 - 2.4e-20 73.0 0.1 4.3e-15 55.8 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ66319.1 - 4.8e-10 39.2 0.0 0.00045 19.6 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Cep57_CLD_2 PF14197.6 CDJ66321.1 - 2.1e-05 24.5 0.7 2.1e-05 24.5 0.7 4.8 4 1 0 4 4 4 1 Centrosome localisation domain of PPC89 FH2 PF02181.23 CDJ66321.1 - 2.6e-05 23.5 0.1 2.6e-05 23.5 0.1 3.4 2 1 2 4 4 4 1 Formin Homology 2 Domain ABC_membrane PF00664.23 CDJ66321.1 - 0.038 13.6 0.8 0.093 12.4 0.8 1.6 1 0 0 1 1 1 0 ABC transporter transmembrane region CdiI PF07262.11 CDJ66321.1 - 0.12 12.2 0.3 0.28 10.9 0.3 1.6 1 0 0 1 1 1 0 CDI immunity protein Prominin PF05478.11 CDJ66321.1 - 0.27 9.1 17.9 0.56 8.1 17.9 1.4 1 0 0 1 1 1 0 Prominin SR-25 PF10500.9 CDJ66322.1 - 0.0011 18.6 26.1 0.0015 18.2 26.1 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ66322.1 - 0.0027 18.0 25.0 0.0035 17.6 25.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) CDK2AP PF09806.9 CDJ66322.1 - 0.051 13.6 15.5 0.057 13.5 15.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1645 PF07816.11 CDJ66322.1 - 0.1 13.2 16.8 0.12 13.0 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Calici_coat_C PF08435.11 CDJ66322.1 - 0.15 11.5 2.8 0.17 11.4 2.8 1.1 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal Spt20 PF12090.8 CDJ66322.1 - 0.16 11.5 15.3 0.18 11.4 15.3 1.1 1 0 0 1 1 1 0 Spt20 family Lin-8 PF03353.15 CDJ66322.1 - 0.26 10.8 10.2 0.27 10.8 10.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Paf1 PF03985.13 CDJ66322.1 - 0.31 10.0 7.8 0.36 9.8 7.8 1.0 1 0 0 1 1 1 0 Paf1 FliD_N PF02465.18 CDJ66322.1 - 0.33 11.7 14.9 0.28 11.9 13.9 1.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus AF-4 PF05110.13 CDJ66322.1 - 0.65 8.0 29.4 0.71 7.9 29.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GREB1 PF15782.5 CDJ66322.1 - 0.77 6.8 13.7 0.83 6.7 13.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MPM1 PF17234.2 CDJ66322.1 - 0.99 9.6 9.0 1.2 9.4 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF4667 PF15700.5 CDJ66322.1 - 1 9.4 19.9 1.1 9.2 19.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Kinesin_assoc PF16183.5 CDJ66322.1 - 1.3 9.1 4.2 1.4 9.1 4.2 1.1 1 0 0 1 1 1 0 Kinesin-associated DUF4692 PF15763.5 CDJ66322.1 - 1.6 9.2 13.2 1.8 9.0 13.2 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Roughex PF06020.11 CDJ66322.1 - 2.1 7.4 8.9 2.5 7.1 8.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein CCDC106 PF15794.5 CDJ66322.1 - 2.2 8.0 18.1 2.6 7.7 18.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Rrn6 PF10214.9 CDJ66322.1 - 2.8 6.3 21.0 3.1 6.2 21.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Apt1 PF10351.9 CDJ66322.1 - 4.8 5.9 17.7 5.2 5.8 17.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ66322.1 - 8 5.1 13.9 8 5.1 13.9 1.0 1 0 0 1 1 1 0 Presenilin Mem_trans PF03547.18 CDJ66322.1 - 8.6 4.6 7.9 9.5 4.5 7.9 1.0 1 0 0 1 1 1 0 Membrane transport protein RskA PF10099.9 CDJ66323.1 - 0.011 16.0 23.6 0.052 13.9 5.4 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ66323.1 - 1.1 9.9 32.2 0.12 13.0 7.6 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein SR-25 PF10500.9 CDJ66323.1 - 1.4 8.5 7.1 2.4 7.7 7.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Adeno_PV PF03910.13 CDJ66323.1 - 8.4 5.0 14.7 0.054 12.2 1.6 2.1 2 0 0 2 2 2 0 Adenovirus minor core protein PV UAA PF08449.11 CDJ66324.1 - 6.3e-38 130.7 16.6 8.6e-38 130.2 16.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDJ66324.1 - 1.2e-05 25.5 26.5 7.8e-05 22.9 7.6 2.8 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CDJ66324.1 - 5.7e-05 22.4 5.4 0.013 14.7 1.1 2.4 2 1 0 2 2 2 2 Nucleotide-sugar transporter DUF5336 PF17270.2 CDJ66324.1 - 0.012 15.3 0.2 0.012 15.3 0.2 3.4 2 1 0 3 3 3 0 Family of unknown function (DUF5336) CNDH2_M PF16869.5 CDJ66324.1 - 1.9 9.1 3.4 2.3 8.9 0.0 2.1 2 0 0 2 2 2 0 PF16858 SelP_N PF04592.14 CDJ66324.1 - 6.6 6.1 10.0 10 5.4 10.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIA PF03153.13 CDJ66325.1 - 0.0021 18.1 27.4 0.0021 18.1 27.4 3.2 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.11 CDJ66325.1 - 0.0024 18.1 18.6 0.0024 18.1 18.6 5.1 4 1 0 4 4 4 1 Domain of unknown function (DUF755) DUF4667 PF15700.5 CDJ66325.1 - 0.0054 16.9 2.5 0.0054 16.9 2.5 3.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4667) AF-4 PF05110.13 CDJ66325.1 - 0.008 14.3 55.6 0.15 10.1 24.6 3.2 3 0 0 3 3 3 3 AF-4 proto-oncoprotein FAM60A PF15396.6 CDJ66325.1 - 0.098 12.6 11.1 0.17 11.8 1.4 3.2 3 0 0 3 3 3 0 Protein Family FAM60A XRN_M PF17846.1 CDJ66325.1 - 0.47 9.3 6.1 0.15 10.9 2.5 1.9 2 0 0 2 2 2 0 Xrn1 helical domain SAPS PF04499.15 CDJ66325.1 - 0.55 9.0 6.9 0.74 8.5 1.5 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SR-25 PF10500.9 CDJ66325.1 - 0.63 9.6 73.9 0.22 11.1 5.3 4.0 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein FAM76 PF16046.5 CDJ66325.1 - 9.6 5.5 19.6 3.2 7.0 0.8 2.5 3 0 0 3 3 3 0 FAM76 protein FAM176 PF14851.6 CDJ66325.1 - 9.9 5.8 11.6 1.2 8.8 2.5 3.0 3 0 0 3 3 3 0 FAM176 family RskA PF10099.9 CDJ66326.1 - 0.0025 18.2 0.5 0.0025 18.2 0.5 4.7 2 1 2 4 4 4 1 Anti-sigma-K factor rskA RIX1 PF08167.12 CDJ66326.1 - 0.077 12.7 0.0 0.077 12.7 0.0 1.8 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis PDEase_I PF00233.19 CDJ66326.1 - 0.35 10.6 3.5 0.17 11.5 0.4 2.1 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_60s PF00428.19 CDJ66326.1 - 0.99 10.0 41.2 0.51 11.0 0.9 4.1 4 0 0 4 4 4 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ66327.1 - 2.2 7.8 17.7 2.3 7.8 17.7 1.1 1 0 0 1 1 1 0 Spt20 family BAF1_ABF1 PF04684.13 CDJ66327.1 - 8.9 5.2 10.1 9.2 5.2 10.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MORN PF02493.20 CDJ66328.1 - 2.9e-30 102.3 41.2 8.4e-08 31.7 1.6 7.6 7 1 0 7 7 7 5 MORN repeat Tudor_2 PF18104.1 CDJ66328.1 - 0.016 14.9 11.8 1.5 8.6 0.2 4.7 5 0 0 5 5 5 0 Jumonji domain-containing protein 2A Tudor domain GTP_EFTU_D2 PF03144.25 CDJ66328.1 - 0.027 14.8 0.1 17 5.9 0.0 3.0 4 0 0 4 4 4 0 Elongation factor Tu domain 2 Kin17_mid PF10357.9 CDJ66328.1 - 0.071 13.0 5.3 0.11 12.4 5.3 1.2 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Presenilin PF01080.17 CDJ66328.1 - 2.2 6.9 4.0 2.2 7.0 4.0 1.0 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ66328.1 - 4.9 6.7 21.4 6 6.4 21.4 1.1 1 0 0 1 1 1 0 Spt20 family Leo1 PF04004.13 CDJ66329.1 - 1.1e-06 28.6 0.2 3.3e-06 27.0 0.2 1.8 1 0 0 1 1 1 1 Leo1-like protein Spt20 PF12090.8 CDJ66329.1 - 0.015 15.0 11.1 0.027 14.1 11.1 1.5 1 0 0 1 1 1 0 Spt20 family DUF4893 PF16233.5 CDJ66329.1 - 0.024 14.2 0.3 0.024 14.2 0.3 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4893) DUF5597 PF18120.1 CDJ66329.1 - 0.041 14.0 0.3 0.041 14.0 0.3 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF5597) DUF2722 PF10846.8 CDJ66329.1 - 0.079 11.9 6.4 0.16 10.9 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Ipi1_N PF12333.8 CDJ66330.1 - 0.047 14.3 1.4 0.11 13.0 1.4 1.6 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Tam41_Mmp37 PF09139.11 CDJ66330.1 - 0.8 9.1 3.2 1.2 8.5 3.2 1.1 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial PGA2 PF07543.12 CDJ66330.1 - 3.5 7.6 7.3 0.88 9.5 3.0 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 RskA PF10099.9 CDJ66331.1 - 0.0069 16.7 17.2 0.24 11.7 1.4 2.3 2 0 0 2 2 2 2 Anti-sigma-K factor rskA Roughex PF06020.11 CDJ66331.1 - 0.68 9.0 15.3 1 8.4 15.3 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Bac_luciferase PF00296.20 CDJ66331.1 - 3.3 7.1 12.1 1.1 8.6 6.2 2.1 2 0 0 2 2 2 0 Luciferase-like monooxygenase CK_II_beta PF01214.18 CDJ66332.1 - 1.1e-41 142.7 0.3 2.4e-40 138.3 0.0 2.1 2 0 0 2 2 2 1 Casein kinase II regulatory subunit TFIIA PF03153.13 CDJ66332.1 - 4.5e-05 23.6 13.5 6.3e-05 23.2 13.5 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ66332.1 - 0.0011 19.0 12.9 0.0013 18.7 12.9 1.1 1 0 0 1 1 1 1 SPX domain Med15 PF09606.10 CDJ66332.1 - 0.014 14.2 20.8 0.017 13.8 20.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Methyltransf_34 PF11312.8 CDJ66332.1 - 0.068 12.4 5.2 0.095 11.9 5.2 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase SOG2 PF10428.9 CDJ66332.1 - 0.15 11.3 15.0 0.22 10.7 15.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 CDJ66332.1 - 0.29 9.8 8.6 0.41 9.3 8.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WES_acyltransf PF03007.16 CDJ66332.1 - 0.3 10.8 6.9 0.45 10.2 6.9 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Pol_alpha_B_N PF08418.10 CDJ66332.1 - 0.31 11.0 15.6 0.43 10.5 15.6 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF4647 PF15504.6 CDJ66332.1 - 0.39 9.8 9.8 0.52 9.4 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) BAF1_ABF1 PF04684.13 CDJ66332.1 - 0.67 8.9 16.4 1 8.3 16.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SLC12 PF03522.15 CDJ66332.1 - 0.91 8.5 9.3 1.3 8.0 9.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 MAP65_ASE1 PF03999.12 CDJ66332.1 - 1.2 7.7 12.3 1.7 7.2 12.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Macoilin PF09726.9 CDJ66332.1 - 1.5 7.3 20.3 2.1 6.8 20.3 1.1 1 0 0 1 1 1 0 Macoilin family MCU PF04678.13 CDJ66332.1 - 2.2 8.3 5.9 4.4 7.4 5.9 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Ribosomal_60s PF00428.19 CDJ66332.1 - 3 8.5 19.1 2.1 9.0 15.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3138 PF11336.8 CDJ66332.1 - 3.6 6.1 17.4 5.5 5.5 17.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF966 PF06136.13 CDJ66332.1 - 4.3 7.0 16.8 5.7 6.5 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SARAF PF06682.12 CDJ66332.1 - 4.6 6.8 17.9 6.4 6.3 17.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Presenilin PF01080.17 CDJ66332.1 - 5.2 5.7 15.9 9.1 4.9 15.9 1.4 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.12 CDJ66332.1 - 7.5 5.1 13.7 9.6 4.7 13.7 1.1 1 0 0 1 1 1 0 Hamartin protein PAP1 PF08601.10 CDJ66332.1 - 9.3 5.9 22.6 13 5.4 22.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 TFIIA PF03153.13 CDJ66334.1 - 4.2e-05 23.7 54.6 5.8e-05 23.3 54.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 CDJ66334.1 - 1.9 7.1 20.3 2.3 6.8 20.3 1.2 1 0 0 1 1 1 0 Hamartin protein DUF4551 PF15087.6 CDJ66334.1 - 3 6.6 24.8 3.9 6.2 24.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ins_allergen_rp PF06757.13 CDJ66336.1 - 0.028 14.4 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification DUF592 PF04574.13 CDJ66337.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) RNA_pol_Rpb1_R PF05001.13 CDJ66338.1 - 0.052 13.9 2.9 0.17 12.3 2.9 2.0 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat SNAPc_SNAP43 PF09808.9 CDJ66339.1 - 0.028 14.3 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 AAA_6 PF12774.7 CDJ66340.1 - 2e-148 493.7 1.9 9.6e-148 491.5 0.1 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CDJ66340.1 - 2.1e-92 309.2 0.3 4.2e-91 304.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CDJ66340.1 - 1.9e-79 265.4 0.0 1e-72 243.4 0.0 3.5 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_5 PF07728.14 CDJ66340.1 - 2.4e-28 98.9 0.0 4.3e-09 36.5 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDJ66340.1 - 9.5e-26 90.4 0.3 8.6e-25 87.3 0.0 2.8 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ66340.1 - 1.5e-21 76.5 0.0 5e-21 74.8 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDJ66340.1 - 2.9e-12 47.2 0.0 0.0069 16.8 0.0 4.7 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ66340.1 - 2.7e-09 37.6 3.5 0.31 11.4 0.0 6.3 7 1 1 8 8 6 2 AAA ATPase domain AAA_22 PF13401.6 CDJ66340.1 - 2.3e-08 34.4 2.3 0.22 11.8 0.0 4.9 5 0 0 5 5 4 3 AAA domain DUF853 PF05872.12 CDJ66340.1 - 1.8e-06 26.9 0.3 0.3 9.6 0.0 3.2 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) AAA_18 PF13238.6 CDJ66340.1 - 2.9e-06 27.9 0.0 0.076 13.6 0.0 4.3 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 CDJ66340.1 - 1.3e-05 25.6 0.0 0.12 12.7 0.0 4.2 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.6 CDJ66340.1 - 3.2e-05 24.2 0.2 2.9 8.1 0.0 5.1 5 0 0 5 5 5 1 AAA domain AAA_30 PF13604.6 CDJ66340.1 - 5.2e-05 23.1 0.2 1 9.1 0.1 3.5 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 CDJ66340.1 - 0.00028 20.0 2.6 0.87 8.6 0.0 4.0 4 0 0 4 4 4 2 Type II/IV secretion system protein Mg_chelatase PF01078.21 CDJ66340.1 - 0.0003 20.2 0.9 3.5 7.0 0.0 4.2 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 CDJ66340.1 - 0.00095 18.8 0.8 1.3 8.6 0.0 3.8 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain Sigma54_activat PF00158.26 CDJ66340.1 - 0.0011 18.7 0.1 17 5.1 0.0 3.9 4 0 0 4 4 3 0 Sigma-54 interaction domain AAA_25 PF13481.6 CDJ66340.1 - 0.0013 18.3 5.6 7.2 6.1 0.1 4.5 4 0 0 4 4 4 0 AAA domain DEAD PF00270.29 CDJ66340.1 - 0.0027 17.5 0.0 1.1 9.0 0.0 3.3 3 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_33 PF13671.6 CDJ66340.1 - 0.0028 17.8 0.1 16 5.7 0.0 4.0 4 0 0 4 4 3 0 AAA domain TsaE PF02367.17 CDJ66340.1 - 0.0035 17.3 1.3 6.1 6.9 0.2 3.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 CDJ66340.1 - 0.0037 17.3 0.2 11 6.0 0.0 3.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 CDJ66340.1 - 0.0048 16.6 0.1 7.6 6.2 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_19 PF13245.6 CDJ66340.1 - 0.0088 16.4 2.0 15 5.9 0.3 4.0 4 1 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 CDJ66340.1 - 0.068 12.4 0.6 6.1 6.1 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin AAA_11 PF13086.6 CDJ66340.1 - 0.069 12.9 0.1 8 6.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 CDJ66340.1 - 0.083 13.0 0.0 2.7 8.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 CDJ66340.1 - 0.096 12.6 0.1 9.1 6.1 0.0 3.5 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_lid_7 PF17867.1 CDJ66340.1 - 0.1 12.8 0.0 0.52 10.5 0.0 2.3 1 0 0 1 1 1 0 Midasin AAA lid domain Cytidylate_kin PF02224.18 CDJ66340.1 - 0.14 11.9 0.1 1.4 8.6 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_24 PF13479.6 CDJ66340.1 - 0.19 11.4 0.2 34 4.1 0.0 3.7 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 CDJ66340.1 - 0.2 11.5 0.9 35 4.3 0.0 3.8 3 1 0 3 3 3 0 NACHT domain Sec2p PF06428.11 CDJ66340.1 - 0.26 11.3 5.0 0.28 11.2 1.7 2.6 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Dynein_C PF18199.1 CDJ66341.1 - 7.9e-105 350.4 0.0 1.9e-104 349.2 0.0 1.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CDJ66341.1 - 1.7e-82 275.9 0.1 7.7e-82 273.7 0.1 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 CDJ66341.1 - 1.8e-54 184.0 0.0 4e-54 182.8 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ66341.1 - 1.2e-49 167.4 0.0 4.1e-46 155.9 0.0 2.8 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain bZIP_1 PF00170.21 CDJ66341.1 - 0.073 13.2 1.1 0.16 12.1 1.1 1.6 1 0 0 1 1 1 0 bZIP transcription factor MnmE_helical PF12631.7 CDJ66341.1 - 0.13 12.4 0.2 0.32 11.1 0.1 1.7 2 0 0 2 2 2 0 MnmE helical domain DUF2316 PF10078.9 CDJ66341.1 - 0.21 11.9 1.1 22 5.4 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Cullin_Nedd8 PF10557.9 CDJ66344.1 - 4.5e-10 39.4 0.1 8.9e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain Calreticulin PF00262.18 CDJ66345.1 - 2e-33 115.7 0.0 5e-32 111.2 0.0 2.1 1 1 1 2 2 2 2 Calreticulin family Birna_VP5 PF03042.14 CDJ66345.1 - 0.068 13.2 0.1 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Birnavirus VP5 protein Phage_AlpA PF05930.12 CDJ66346.1 - 0.037 13.8 0.0 0.94 9.3 0.0 2.3 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) SR-25 PF10500.9 CDJ66347.1 - 0.011 15.4 31.3 0.27 10.8 8.8 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ66347.1 - 0.064 13.2 9.7 0.074 13.0 9.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 CDJ66348.1 - 2.7e-05 24.3 29.3 0.013 15.6 16.4 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ66348.1 - 0.0007 18.7 25.8 0.034 13.1 3.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) DUF1645 PF07816.11 CDJ66348.1 - 0.00083 20.0 2.9 0.00083 20.0 2.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1645) DUF2828 PF11443.8 CDJ66348.1 - 0.0028 15.9 4.0 0.0042 15.2 4.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) RskA PF10099.9 CDJ66348.1 - 0.0069 16.7 28.7 0.026 14.8 14.7 2.8 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF4050 PF13259.6 CDJ66348.1 - 0.0087 16.4 3.5 0.013 15.9 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) DUF3371 PF11851.8 CDJ66348.1 - 0.009 17.1 16.2 0.38 11.9 9.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3371) RPA43_OB PF17875.1 CDJ66348.1 - 0.054 14.1 4.4 0.41 11.3 0.3 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I BRF1 PF07741.13 CDJ66348.1 - 0.084 13.2 14.2 0.78 10.1 8.6 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Med15 PF09606.10 CDJ66348.1 - 0.09 11.4 39.1 0.45 9.2 12.1 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MDM10 PF12519.8 CDJ66348.1 - 0.091 11.6 5.1 0.13 11.1 5.1 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CPSF100_C PF13299.6 CDJ66348.1 - 0.15 12.3 8.3 0.39 10.9 3.4 2.6 3 0 0 3 3 2 0 Cleavage and polyadenylation factor 2 C-terminal TERB2 PF15101.6 CDJ66348.1 - 0.16 12.0 20.7 0.043 13.9 8.2 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 EPL1 PF10513.9 CDJ66348.1 - 0.2 12.0 12.9 0.32 11.4 4.0 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like BORG_CEP PF14957.6 CDJ66348.1 - 0.21 12.7 5.5 1.4 10.1 2.8 2.3 2 0 0 2 2 2 0 Cdc42 effector Connexin PF00029.19 CDJ66348.1 - 0.23 11.2 7.7 0.41 10.4 3.7 2.0 2 0 0 2 2 2 0 Connexin Coilin_N PF15862.5 CDJ66348.1 - 0.31 10.8 17.9 0.037 13.8 5.5 2.5 2 0 0 2 2 2 0 Coilin N-terminus Pex14_N PF04695.13 CDJ66348.1 - 0.32 11.6 22.2 0.22 12.2 8.6 2.6 3 0 0 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5523 PF17661.1 CDJ66348.1 - 0.48 10.1 12.7 0.085 12.5 4.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5523) HemX PF04375.14 CDJ66348.1 - 0.56 9.4 30.6 0.063 12.6 12.6 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase SpoIIP PF07454.11 CDJ66348.1 - 0.64 9.4 13.3 0.15 11.5 5.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) HNOBA PF07701.14 CDJ66348.1 - 0.89 8.9 13.9 0.27 10.6 7.0 2.1 2 0 0 2 2 2 0 Heme NO binding associated EIIBC-GUT_N PF03612.14 CDJ66348.1 - 0.9 9.3 15.8 2.5 7.8 10.8 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus UPF0560 PF10577.9 CDJ66348.1 - 0.98 7.8 26.1 0.71 8.3 12.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 ATAD4 PF15321.6 CDJ66348.1 - 1 10.7 9.4 4.7 8.6 2.4 2.3 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Tim54 PF11711.8 CDJ66348.1 - 1.2 7.8 11.8 5.2 5.7 0.1 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pinin_SDK_memA PF04696.13 CDJ66348.1 - 1.7 8.7 33.2 0.28 11.3 19.1 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Suf PF05843.14 CDJ66348.1 - 1.8 8.5 18.1 1.1 9.1 7.6 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) CCDC53 PF10152.9 CDJ66348.1 - 1.9 8.9 16.5 4.5 7.7 16.5 1.6 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Peptidase_U57 PF05582.12 CDJ66348.1 - 1.9 7.7 9.4 0.74 9.0 3.5 2.1 2 0 0 2 2 2 0 YabG peptidase U57 Band_3_cyto PF07565.13 CDJ66348.1 - 2 8.1 13.5 1 9.1 5.1 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4647 PF15504.6 CDJ66348.1 - 2 7.4 19.9 0.066 12.3 7.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) eIF-3_zeta PF05091.12 CDJ66348.1 - 3.2 6.6 23.2 0.66 8.9 10.7 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rxt3 PF08642.10 CDJ66348.1 - 3.2 8.5 7.4 2.8 8.7 2.1 2.1 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Afi1 PF07792.12 CDJ66348.1 - 3.5 8.1 15.4 2.3 8.7 8.4 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Bud13 PF09736.9 CDJ66348.1 - 3.5 8.0 21.9 2.6 8.4 0.9 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Vif PF00559.17 CDJ66348.1 - 4 7.1 9.3 9.6 5.8 9.3 1.6 1 0 0 1 1 1 0 Retroviral Vif (Viral infectivity) protein HA2 PF04408.23 CDJ66348.1 - 4.6 7.6 16.0 2.4 8.5 5.0 2.5 2 1 0 2 2 2 0 Helicase associated domain (HA2) Peptidase_S49_N PF08496.10 CDJ66348.1 - 4.6 7.3 19.7 1.5 8.9 11.7 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Gastrin PF00918.17 CDJ66348.1 - 4.7 8.2 12.4 7 7.6 7.4 2.4 2 0 0 2 2 2 0 Gastrin/cholecystokinin family MPM1 PF17234.2 CDJ66348.1 - 4.9 7.4 18.9 3.7 7.8 9.7 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 CRF1 PF10380.9 CDJ66348.1 - 6.7 7.1 8.3 28 5.1 0.0 2.3 2 0 0 2 2 2 0 Transcription factor CRF1 MDM31_MDM32 PF08118.11 CDJ66348.1 - 7.1 5.2 8.2 18 3.9 5.7 2.0 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF2048 PF09752.9 CDJ66348.1 - 8.4 5.4 11.5 7.2 5.6 5.0 2.1 2 0 0 2 2 2 0 Abhydrolase domain containing 18 DUF5327 PF17261.2 CDJ66348.1 - 8.5 7.2 25.6 12 6.7 2.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) TFB6 PF17110.5 CDJ66348.1 - 9 6.0 8.4 1.6 8.5 2.1 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF4770 PF15994.5 CDJ66348.1 - 9 6.5 19.9 0.78 10.0 9.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) tRNA-synt_1e PF01406.19 CDJ66349.1 - 2.4e-25 89.5 0.0 2.9e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Macoilin PF09726.9 CDJ66349.1 - 0.094 11.3 0.3 0.086 11.4 0.3 1.0 1 0 0 1 1 1 0 Macoilin family DUF1117 PF06547.12 CDJ66349.1 - 1.2 9.7 7.1 0.78 10.3 5.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Ndc1_Nup PF09531.10 CDJ66350.1 - 0.95 8.1 20.9 1.2 7.8 20.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_34 PF11312.8 CDJ66350.1 - 0.99 8.6 10.8 1.8 7.7 10.8 1.5 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase Dicty_REP PF05086.12 CDJ66351.1 - 0.68 7.8 3.0 1.3 6.9 3.0 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein POPLD PF08170.12 CDJ66352.1 - 2.6 8.4 5.1 19 5.7 0.2 2.5 2 0 0 2 2 2 0 POPLD (NUC188) domain RskA PF10099.9 CDJ66353.1 - 0.0098 16.2 28.4 0.014 15.7 23.2 2.2 1 1 1 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ66353.1 - 0.015 15.3 34.6 0.022 14.7 34.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ66353.1 - 0.21 10.6 10.6 0.28 10.2 10.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Smg8_Smg9 PF10220.9 CDJ66353.1 - 0.86 7.8 12.8 1.1 7.4 12.8 1.3 1 0 0 1 1 1 0 Smg8_Smg9 eIF-3_zeta PF05091.12 CDJ66353.1 - 6.5 5.6 15.2 9.4 5.1 15.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf-CCHC PF00098.23 CDJ66354.1 - 2e-08 33.9 15.2 3.1e-06 27.0 2.3 3.6 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ66354.1 - 0.0017 18.3 0.1 0.0017 18.3 0.1 2.4 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ66354.1 - 0.0023 17.7 0.6 0.0023 17.7 0.6 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ66354.1 - 0.016 15.0 1.9 0.016 15.0 1.9 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ66354.1 - 0.048 13.4 5.7 0.31 10.8 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF3425 PF11905.8 CDJ66354.1 - 0.098 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) zf-CCHC_5 PF14787.6 CDJ66354.1 - 1.2 8.9 10.7 1.5 8.6 1.8 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DnaJ_CXXCXGXG PF00684.19 CDJ66354.1 - 2.3 8.7 12.2 5.4 7.5 12.2 1.7 1 1 0 1 1 1 0 DnaJ central domain NYAP_N PF15439.6 CDJ66355.1 - 0.037 13.2 4.8 0.91 8.7 4.8 2.5 1 1 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DDOST_48kD PF03345.14 CDJ66356.1 - 5.7e-48 163.8 0.0 8.7e-44 150.0 0.0 2.2 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta 2OG-FeII_Oxy_3 PF13640.6 CDJ66356.1 - 3.3e-10 40.7 0.0 9.4e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 CDJ66356.1 - 0.0019 17.4 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Poxvirus C4/C10 protein 2OG-FeII_Oxy_5 PF13759.6 CDJ66356.1 - 0.023 15.1 0.0 0.092 13.2 0.0 2.0 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase TPR_14 PF13428.6 CDJ66356.1 - 0.14 13.0 0.4 0.59 11.1 0.4 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 CDJ66357.1 - 9.9e-11 41.6 0.0 2.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF3613 PF12266.8 CDJ66357.1 - 0.0053 16.5 2.6 0.0053 16.5 2.6 3.1 2 1 0 3 3 3 1 Protein of unknown function (DUF3613) RE_XamI PF09572.10 CDJ66357.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 XamI restriction endonuclease zf-RING_UBOX PF13445.6 CDJ66357.1 - 0.035 14.1 0.2 0.098 12.7 0.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger LPP20 PF02169.16 CDJ66357.1 - 0.16 12.3 2.7 0.37 11.2 2.7 1.5 1 0 0 1 1 1 0 LPP20 lipoprotein DUF1754 PF08555.10 CDJ66357.1 - 2.3 9.1 7.1 0.16 12.7 0.6 2.1 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Ima1_N PF09779.9 CDJ66357.1 - 4.3 8.2 8.3 2 9.3 5.4 1.8 1 1 1 2 2 2 0 Ima1 N-terminal domain Bud13 PF09736.9 CDJ66359.1 - 5.6e-38 130.6 5.4 5.6e-38 130.6 5.4 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex AAA PF00004.29 CDJ66360.1 - 1.7e-39 135.3 0.0 3.3e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ66360.1 - 5.9e-09 35.6 0.2 1.3e-08 34.5 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDJ66360.1 - 7.4e-05 23.2 4.5 0.0023 18.3 0.4 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CDJ66360.1 - 0.0004 20.7 0.5 0.051 13.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CDJ66360.1 - 0.00071 19.6 0.1 0.003 17.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CDJ66360.1 - 0.0039 16.4 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 CDJ66360.1 - 0.015 14.8 0.0 0.048 13.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CDJ66360.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 CDJ66360.1 - 0.02 14.4 0.2 0.037 13.5 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 CDJ66360.1 - 0.042 14.0 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CDJ66360.1 - 0.05 13.4 0.1 0.16 11.7 0.0 1.8 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CDJ66360.1 - 0.053 13.8 0.3 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ66360.1 - 0.054 13.4 1.9 0.099 12.6 0.1 2.4 3 1 0 3 3 2 0 NACHT domain Mg_chelatase PF01078.21 CDJ66360.1 - 0.064 12.6 0.2 0.16 11.3 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_6 PF12774.7 CDJ66360.1 - 0.083 11.8 0.0 7.5 5.4 0.1 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 CDJ66360.1 - 0.16 12.0 0.1 0.29 11.1 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SR-25 PF10500.9 CDJ66361.1 - 2.1 7.9 10.5 3.7 7.1 10.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.22 CDJ66362.1 - 5.6e-37 125.4 0.1 3e-17 62.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ66362.1 - 2.7e-05 24.1 0.0 0.024 14.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CDJ66362.1 - 3.9e-05 23.4 0.0 0.0077 16.1 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CDJ66362.1 - 0.017 15.2 0.0 0.65 10.2 0.0 3.0 2 1 0 2 2 2 0 RNA recognition motif DUF418 PF04235.12 CDJ66363.1 - 0.11 12.5 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) DUF2681 PF10883.8 CDJ66363.1 - 0.71 10.3 8.4 17 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) AMP-binding PF00501.28 CDJ66364.1 - 9e-16 57.5 0.0 1.9e-15 56.4 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme Vmethyltransf_C PF08456.10 CDJ66364.1 - 0.16 11.5 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral methyltransferase C-terminal AMP-binding PF00501.28 CDJ66365.1 - 2.5e-37 128.5 0.0 3.3e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ66365.1 - 2.5e-05 25.1 0.1 5.8e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RVP_2 PF08284.11 CDJ66366.1 - 0.22 11.3 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Utp13 PF08625.11 CDJ66368.1 - 3.8e-11 43.1 1.3 3.8e-11 43.1 1.3 3.2 3 1 0 3 3 2 1 Utp13 specific WD40 associated domain DUF2052 PF09747.9 CDJ66368.1 - 0.058 13.5 22.0 0.76 9.9 16.5 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) O-antigen_lig PF13425.6 CDJ66368.1 - 0.18 10.5 1.9 0.26 10.0 1.9 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RR_TM4-6 PF06459.12 CDJ66368.1 - 0.27 11.0 20.9 0.057 13.2 14.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TCP PF03634.13 CDJ66368.1 - 0.28 11.7 22.6 0.33 11.5 16.5 2.7 2 1 1 3 3 3 0 TCP family transcription factor GAGA_bind PF06217.12 CDJ66368.1 - 0.39 11.0 19.7 0.16 12.3 11.8 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Folliculin PF11704.8 CDJ66368.1 - 0.39 10.6 17.7 0.38 10.6 11.2 2.5 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport BAF1_ABF1 PF04684.13 CDJ66368.1 - 0.5 9.4 14.6 0.075 12.1 9.6 1.9 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ66368.1 - 1.4 7.6 22.0 0.3 9.8 15.3 2.1 2 0 0 2 2 2 0 Presenilin V_ATPase_I PF01496.19 CDJ66368.1 - 1.6 6.6 21.1 0.13 10.1 14.8 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Suf PF05843.14 CDJ66368.1 - 2 8.3 27.4 6.6 6.6 19.7 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 CDJ66368.1 - 2.1 6.5 33.4 1.5 7.0 23.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ66368.1 - 2.4 7.3 6.7 4.6 6.4 6.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4667 PF15700.5 CDJ66368.1 - 4.9 7.2 22.4 1.1 9.3 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) THOC2_N PF16134.5 CDJ66368.1 - 5 5.6 23.8 0.047 12.3 13.8 1.9 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus Allexi_40kDa PF05549.11 CDJ66368.1 - 6.3 6.2 12.7 0.87 9.0 6.7 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein ABC1 PF03109.16 CDJ66370.1 - 6.1e-33 113.5 0.6 1.2e-32 112.6 0.4 1.6 1 1 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CDJ66370.1 - 0.015 14.9 0.0 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 CDJ66370.1 - 0.5 10.3 2.9 0.4 10.5 0.2 2.3 2 2 0 2 2 2 0 Phosphotransferase enzyme family Exonuc_VII_L PF02601.15 CDJ66371.1 - 0.036 13.6 12.0 0.031 13.8 10.9 1.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.9 CDJ66371.1 - 1.2 7.4 17.9 1.4 7.1 17.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ66371.1 - 1.4 7.6 7.9 1.9 7.1 7.9 1.2 1 0 0 1 1 1 0 Presenilin Med15 PF09606.10 CDJ66371.1 - 2.5 6.7 46.4 3.7 6.1 46.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal eIF-3_zeta PF05091.12 CDJ66371.1 - 4.2 6.2 11.6 5.6 5.8 11.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Nucleo_P87 PF07267.11 CDJ66371.1 - 5.6 5.7 8.5 6.8 5.4 8.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Alg14 PF08660.11 CDJ66372.1 - 0.69 9.8 2.5 0.74 9.7 2.5 1.1 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like Tim54 PF11711.8 CDJ66372.1 - 1.3 7.7 19.6 1.3 7.7 19.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CobT PF06213.12 CDJ66372.1 - 2.8 7.2 34.3 3 7.2 34.3 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pex14_N PF04695.13 CDJ66372.1 - 3 8.5 34.8 3.2 8.4 34.8 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ureide_permease PF07168.11 CDJ66372.1 - 5 5.8 10.6 4.5 5.9 10.6 1.1 1 0 0 1 1 1 0 Ureide permease GNAT_acetyltr_2 PF13718.6 CDJ66372.1 - 6.9 6.0 16.8 8.1 5.8 16.8 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 NPR3 PF03666.13 CDJ66372.1 - 8.4 5.1 24.4 8.3 5.1 24.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2828 PF11443.8 CDJ66372.1 - 9.5 4.2 25.3 9.6 4.2 25.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Transketolase_C PF02780.20 CDJ66373.1 - 2.3e-12 46.9 0.1 2.3e-12 46.9 0.1 1.9 2 0 0 2 2 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 CDJ66373.1 - 8.8e-06 25.5 0.0 8.8e-06 25.5 0.0 2.2 2 0 0 2 2 1 1 Transketolase, pyrimidine binding domain PAT1 PF09770.9 CDJ66373.1 - 0.0022 16.4 29.5 0.0025 16.2 29.5 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ66373.1 - 1.9 5.5 15.3 2 5.4 15.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 CDJ66373.1 - 2 7.4 16.0 2.6 7.0 16.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF966 PF06136.13 CDJ66373.1 - 2.3 7.9 12.5 3 7.5 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Presenilin PF01080.17 CDJ66373.1 - 2.5 6.8 20.3 3.7 6.2 20.3 1.2 1 0 0 1 1 1 0 Presenilin CDK5_activator PF03261.15 CDJ66373.1 - 2.9 7.3 13.9 4.1 6.8 13.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Hid1 PF12722.7 CDJ66373.1 - 3.9 5.5 17.7 5.2 5.1 17.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Coilin_N PF15862.5 CDJ66373.1 - 4.1 7.2 25.8 1.3 8.8 4.7 2.2 2 0 0 2 2 2 0 Coilin N-terminus ALMT PF11744.8 CDJ66373.1 - 4.4 6.0 9.2 6.9 5.4 9.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4813 PF16072.5 CDJ66373.1 - 5.5 6.6 29.8 1 9.0 22.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) SPX PF03105.19 CDJ66376.1 - 0.0017 18.4 17.4 0.002 18.1 17.4 1.1 1 0 0 1 1 1 1 SPX domain TFIIA PF03153.13 CDJ66376.1 - 0.75 9.7 12.7 1 9.3 12.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Smg8_Smg9 PF10220.9 CDJ66376.1 - 9.9 4.3 12.1 13 4.0 12.1 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Tctex-1 PF03645.13 CDJ66377.1 - 1.9e-06 28.0 0.0 2.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family HA2 PF04408.23 CDJ66378.1 - 0.021 15.1 1.3 0.021 15.1 1.3 3.2 2 1 0 2 2 2 0 Helicase associated domain (HA2) Connexin PF00029.19 CDJ66378.1 - 0.12 12.1 3.6 0.55 9.9 3.2 2.0 2 0 0 2 2 2 0 Connexin DUF4834 PF16118.5 CDJ66378.1 - 0.18 12.8 10.1 0.17 12.8 5.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Peroxin-13_N PF04088.13 CDJ66378.1 - 0.45 10.8 6.8 0.49 10.7 2.5 2.8 2 0 0 2 2 2 0 Peroxin 13, N-terminal region RskA PF10099.9 CDJ66379.1 - 0.013 15.8 18.3 0.013 15.8 18.3 4.1 1 1 3 4 4 4 0 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ66379.1 - 9.6 6.8 0.0 2.9 8.4 0.5 4.7 2 2 2 4 4 4 0 Domain of unknown function (DUF4179) DGF-1_C PF11040.8 CDJ66380.1 - 0.08 13.0 0.0 0.08 13.0 0.0 3.2 2 1 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus PNISR PF15996.5 CDJ66382.1 - 0.2 11.9 16.4 0.82 9.9 3.4 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR RIFIN PF02009.16 CDJ66382.1 - 1.9 8.3 26.6 0.13 12.1 16.4 2.0 1 1 1 2 2 2 0 Rifin Utp14 PF04615.13 CDJ66382.1 - 3.6 6.0 17.4 5.3 5.5 17.4 1.2 1 0 0 1 1 1 0 Utp14 protein CCSAP PF15748.5 CDJ66383.1 - 0.00022 21.5 5.5 0.0048 17.1 0.1 2.2 2 0 0 2 2 2 2 Centriole, cilia and spindle-associated SR-25 PF10500.9 CDJ66383.1 - 0.0019 17.9 18.0 0.0029 17.3 4.4 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Exonuc_VII_L PF02601.15 CDJ66383.1 - 0.43 10.1 7.5 0.24 10.9 4.7 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit FeoB_associated PF12669.7 CDJ66383.1 - 1.2 9.6 3.1 18 5.8 0.2 3.7 2 1 1 3 3 3 0 FeoB-associated Cys-rich membrane protein Ham1p_like PF01725.16 CDJ66384.1 - 5.5e-23 81.9 1.6 1e-22 81.0 1.6 1.6 1 1 0 1 1 1 1 Ham1 family DUF2722 PF10846.8 CDJ66384.1 - 3.7e-06 26.2 5.8 3.8e-06 26.1 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ66384.1 - 5.5e-05 23.4 5.7 5.5e-05 23.4 5.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.6 CDJ66384.1 - 0.00042 20.3 1.0 0.00089 19.2 1.0 1.5 1 1 0 1 1 1 1 Spore coat protein CotO Presenilin PF01080.17 CDJ66384.1 - 0.089 11.5 0.5 0.082 11.7 0.5 1.1 1 0 0 1 1 1 0 Presenilin Ilar_coat PF01787.16 CDJ66384.1 - 0.12 12.1 2.5 0.16 11.8 2.5 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein Pex14_N PF04695.13 CDJ66384.1 - 0.3 11.7 9.9 0.098 13.3 7.3 1.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ66384.1 - 0.43 10.5 8.3 0.59 10.1 8.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Roughex PF06020.11 CDJ66384.1 - 0.47 9.5 5.9 0.59 9.2 5.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein GTA_holin_3TM PF11351.8 CDJ66384.1 - 0.81 10.2 5.5 1.4 9.5 5.5 1.3 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release DUF4770 PF15994.5 CDJ66384.1 - 2.2 8.5 8.5 0.27 11.5 4.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) eIF-3_zeta PF05091.12 CDJ66384.1 - 3.5 6.5 8.4 4.9 6.0 8.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 CDJ66384.1 - 4.3 6.9 27.6 6.4 6.3 27.6 1.2 1 0 0 1 1 1 0 Spt20 family CDT1 PF08839.11 CDJ66385.1 - 0.0013 19.1 0.5 0.0024 18.2 0.5 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like RNase_H2_suC PF08615.11 CDJ66385.1 - 0.36 11.0 2.0 0.57 10.4 1.8 1.4 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SUIM_assoc PF16619.5 CDJ66385.1 - 0.88 9.7 15.6 0.77 9.9 11.7 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PRC2_HTH_1 PF18118.1 CDJ66386.1 - 0.075 13.8 1.1 0.11 13.3 1.1 1.2 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain SUIM_assoc PF16619.5 CDJ66386.1 - 0.14 12.2 8.5 0.3 11.2 8.5 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ66386.1 - 0.17 11.4 4.8 0.21 11.2 4.8 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ66386.1 - 0.77 9.7 9.5 1.1 9.2 9.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peroxin-3 PF04882.12 CDJ66386.1 - 1.2 8.1 6.9 1.4 7.8 6.9 1.1 1 0 0 1 1 1 0 Peroxin-3 Sporozoite_P67 PF05642.11 CDJ66386.1 - 3.7 5.5 12.7 4.2 5.3 12.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen XPC-binding PF09280.11 CDJ66387.1 - 8e-23 79.9 8.1 8e-23 79.9 8.1 2.4 3 0 0 3 3 3 1 XPC-binding domain UBA PF00627.31 CDJ66387.1 - 1.5e-20 72.7 7.9 1.2e-10 41.1 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 CDJ66387.1 - 3.5e-07 29.9 0.0 3.5e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family SUIM_assoc PF16619.5 CDJ66387.1 - 0.0015 18.6 0.9 0.0015 18.6 0.9 5.0 4 1 1 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ66387.1 - 0.19 11.3 45.9 0.27 10.8 6.4 3.4 3 0 0 3 3 3 0 Spt20 family TBCA PF02970.16 CDJ66388.1 - 3.4e-17 62.6 2.2 3.4e-17 62.6 2.2 3.0 1 1 1 3 3 3 1 Tubulin binding cofactor A SUIM_assoc PF16619.5 CDJ66388.1 - 0.017 15.2 11.6 0.017 15.2 11.6 3.3 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4411 PF14367.6 CDJ66388.1 - 5.2 6.9 8.2 0.16 11.9 1.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4411) ANAPC_CDC26 PF10471.9 CDJ66388.1 - 8.5 7.3 38.3 2.7 8.9 7.4 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 DHH PF01368.20 CDJ66389.1 - 2.4e-09 37.4 0.0 2.4e-09 37.4 0.0 3.1 3 1 0 3 3 3 1 DHH family DDE_Tnp_IS1595 PF12762.7 CDJ66389.1 - 0.051 13.6 0.5 0.23 11.5 0.1 2.2 2 0 0 2 2 2 0 ISXO2-like transposase domain MMR1 PF08505.10 CDJ66389.1 - 2.8 8.1 30.2 0.07 13.4 6.0 3.2 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein tRNA-synt_2b PF00587.25 CDJ66390.1 - 1.3e-07 31.8 0.4 4.3e-07 30.1 0.1 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) SR-25 PF10500.9 CDJ66390.1 - 0.00035 20.2 25.4 0.00035 20.2 25.4 5.5 4 2 1 5 5 5 2 Nuclear RNA-splicing-associated protein DUF898 PF05987.13 CDJ66390.1 - 8.3 5.4 7.4 58 2.6 6.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF1645 PF07816.11 CDJ66391.1 - 7.1 7.2 42.8 2.6 8.6 4.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1645) HGTP_anticodon PF03129.20 CDJ66392.1 - 8.4e-18 64.3 0.0 4.2e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain Apt1 PF10351.9 CDJ66392.1 - 0.00063 18.7 2.9 0.00067 18.6 2.9 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain SPX PF03105.19 CDJ66392.1 - 0.0023 17.9 5.4 0.0029 17.6 5.4 1.1 1 0 0 1 1 1 1 SPX domain Macoilin PF09726.9 CDJ66392.1 - 0.012 14.3 9.3 0.014 14.0 9.3 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 CDJ66392.1 - 0.072 12.6 2.1 0.11 12.0 2.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TRAPPC-Trs85 PF12739.7 CDJ66392.1 - 0.43 9.5 9.1 0.78 8.6 9.1 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit MRI PF15325.6 CDJ66392.1 - 1.8 9.7 7.7 3.5 8.8 7.7 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection RAP1 PF07218.11 CDJ66392.1 - 2.3 6.4 19.3 3.1 6.0 19.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CCDC24 PF15669.5 CDJ66392.1 - 3.8 7.3 7.7 1.4 8.8 4.9 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family RSRP PF17069.5 CDJ66392.1 - 8.1 5.9 28.7 14 5.2 28.7 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 BES1_N PF05687.13 CDJ66392.1 - 9.4 6.6 13.0 18 5.7 13.0 1.5 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal mTERF PF02536.14 CDJ66393.1 - 2.3e-10 39.9 0.1 2.6e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 mTERF RskA PF10099.9 CDJ66393.1 - 0.0011 19.3 12.9 0.0011 19.3 12.9 7.9 2 2 3 6 6 6 1 Anti-sigma-K factor rskA RLL PF10036.9 CDJ66393.1 - 0.013 15.4 2.5 0.013 15.4 2.5 4.9 3 2 0 4 4 4 0 RNA transcription, translation and transport factor protein IF-2B PF01008.17 CDJ66394.1 - 2.5e-16 59.7 0.9 6.6e-16 58.4 0.0 2.1 2 1 0 2 2 2 1 Initiation factor 2 subunit family FAM76 PF16046.5 CDJ66394.1 - 0.14 11.5 26.7 1.2 8.4 0.0 3.2 3 0 0 3 3 3 0 FAM76 protein PAT1 PF09770.9 CDJ66394.1 - 0.19 10.0 39.3 0.15 10.3 28.6 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4770 PF15994.5 CDJ66394.1 - 0.36 11.0 25.7 1.9 8.7 0.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) DUF4471 PF14740.6 CDJ66394.1 - 0.9 8.7 11.7 14 4.8 9.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) eIF-3_zeta PF05091.12 CDJ66394.1 - 2 7.3 30.3 1.3 7.9 0.8 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MPM1 PF17234.2 CDJ66394.1 - 2.3 8.5 23.7 2.7 8.2 12.1 3.3 3 0 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 SPX PF03105.19 CDJ66396.1 - 2.1 8.2 3.3 2.5 7.9 3.3 1.1 1 0 0 1 1 1 0 SPX domain WD40 PF00400.32 CDJ66397.1 - 3.8e-12 46.5 1.3 0.00072 20.3 0.1 4.9 4 1 0 4 4 4 2 WD domain, G-beta repeat Guanylate_cyc PF00211.20 CDJ66399.1 - 8.7e-20 71.1 0.1 6.6e-12 45.4 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF572 PF04502.13 CDJ66401.1 - 4.1e-63 214.0 0.2 9.5e-63 212.8 0.2 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF572) T-box_assoc PF16176.5 CDJ66401.1 - 0.37 10.8 7.5 0.61 10.1 7.5 1.3 1 0 0 1 1 1 0 T-box transcription factor-associated Ribosomal_L11_N PF03946.14 CDJ66402.1 - 5.6e-22 77.4 0.1 1e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CDJ66402.1 - 2.5e-08 34.3 0.2 0.0018 18.8 0.0 2.4 1 1 1 2 2 2 2 Ribosomal protein L11, RNA binding domain NAD_binding_11 PF14833.6 CDJ66402.1 - 0.046 14.0 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Biotin_lipoyl PF00364.22 CDJ66404.1 - 1.4e-11 44.1 1.3 2.4e-11 43.3 1.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme S36_mt PF10937.8 CDJ66404.1 - 0.00051 21.6 0.5 0.00051 21.6 0.5 2.1 2 0 0 2 2 2 1 Ribosomal protein S36, mitochondrial Spt20 PF12090.8 CDJ66404.1 - 0.0056 16.3 5.0 0.0099 15.5 5.0 1.3 1 0 0 1 1 1 1 Spt20 family HlyD_D23 PF16576.5 CDJ66404.1 - 0.019 14.2 0.5 0.053 12.7 0.3 1.7 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CDJ66404.1 - 0.07 13.8 0.5 5.4 7.8 0.2 2.4 1 1 1 2 2 2 0 HlyD family secretion protein Roughex PF06020.11 CDJ66404.1 - 5.9 5.9 8.4 5.9 5.9 6.8 1.7 2 0 0 2 2 2 0 Drosophila roughex protein IMP2_N PF18590.1 CDJ66405.1 - 3.8e-26 91.5 0.1 6e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 CDJ66405.1 - 0.00029 20.7 0.2 0.00052 19.8 0.2 1.4 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain DUF4623 PF15416.6 CDJ66405.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) REPA_OB_2 PF16900.5 CDJ66406.1 - 2.8e-19 68.8 0.0 1.4e-17 63.4 0.0 2.4 2 0 0 2 2 2 1 Replication protein A OB domain Rep_fac-A_C PF08646.10 CDJ66406.1 - 6.1e-08 32.5 0.1 1.1e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain DZR PF12773.7 CDJ66406.1 - 0.085 12.9 0.7 0.23 11.5 0.7 1.8 1 0 0 1 1 1 0 Double zinc ribbon tRNA_anti-codon PF01336.25 CDJ66406.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.9 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Methyltransf_32 PF13679.6 CDJ66408.1 - 0.082 12.9 0.2 0.082 12.9 0.2 3.4 3 1 0 3 3 3 0 Methyltransferase domain BOP1NT PF08145.12 CDJ66409.1 - 5.7e-27 95.3 7.7 1.8e-25 90.4 0.5 3.1 2 1 1 3 3 3 2 BOP1NT (NUC169) domain DUF1645 PF07816.11 CDJ66409.1 - 0.00078 20.1 15.5 0.13 12.8 2.9 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ66409.1 - 0.06 12.9 48.4 0.04 13.5 21.3 2.8 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein PgaD PF13994.6 CDJ66409.1 - 0.16 12.0 0.5 0.31 11.1 0.5 1.4 1 0 0 1 1 1 0 PgaD-like protein ANAPC15 PF15243.6 CDJ66409.1 - 0.2 12.1 0.0 0.2 12.1 0.0 2.6 3 0 0 3 3 2 0 Anaphase-promoting complex subunit 15 Filament_head PF04732.14 CDJ66409.1 - 0.89 10.5 28.4 1.8 9.5 9.3 2.5 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region PigN PF04987.14 CDJ66409.1 - 1.3 7.8 3.3 2.2 7.0 3.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF3464 PF11947.8 CDJ66409.1 - 1.4 8.7 7.2 0.29 10.9 1.4 2.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 RAB3GAP2_N PF14655.6 CDJ66409.1 - 1.5 8.0 8.8 12 5.0 8.8 2.0 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Secretin_N_2 PF07655.13 CDJ66409.1 - 8.8 6.9 23.8 3.4 8.3 7.3 3.0 3 0 0 3 3 3 0 Secretin N-terminal domain EIIBC-GUT_N PF03612.14 CDJ66409.1 - 10 5.8 8.5 0.4 10.4 2.0 1.9 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus GREB1 PF15782.5 CDJ66410.1 - 7.9 3.4 59.5 12 2.9 59.5 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CDJ66411.1 - 0.048 13.7 13.5 0.059 13.4 13.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ66411.1 - 0.074 12.6 11.6 0.093 12.3 11.6 1.1 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ66411.1 - 0.59 10.2 15.6 2.2 8.4 15.6 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 CDJ66411.1 - 1 8.0 2.2 1.2 7.9 2.2 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ66411.1 - 4.4 5.4 9.5 5.1 5.2 9.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Roughex PF06020.11 CDJ66411.1 - 9.6 5.2 6.4 13 4.8 6.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein MutS_V PF00488.21 CDJ66412.1 - 7.7e-32 110.8 0.0 1.5e-31 109.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CDJ66412.1 - 4e-25 89.2 5.1 4e-25 89.2 5.1 2.2 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CDJ66412.1 - 5.1e-08 33.2 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CDJ66412.1 - 1.8e-06 28.3 1.3 0.00072 19.9 0.0 3.1 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 CDJ66412.1 - 2.8e-05 24.4 0.1 5.2e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.6 CDJ66412.1 - 0.19 11.5 0.4 0.42 10.4 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CDJ66412.1 - 0.56 10.7 0.1 0.56 10.7 0.1 3.6 4 0 0 4 4 4 0 AAA domain DUF1645 PF07816.11 CDJ66412.1 - 1.1 9.9 20.4 2.8 8.5 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1645) ASFV_J13L PF05568.11 CDJ66412.1 - 1.4 8.7 11.6 2.9 7.6 11.6 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Utp14 PF04615.13 CDJ66412.1 - 2.7 6.5 7.5 0.058 12.0 0.5 1.7 2 0 0 2 2 2 0 Utp14 protein TFIIA PF03153.13 CDJ66412.1 - 3.2 7.7 24.7 0.23 11.4 8.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cytochrom_C PF00034.21 CDJ66413.1 - 2.7e-05 25.2 0.7 0.00034 21.7 0.0 2.6 2 1 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CDJ66413.1 - 0.00061 20.1 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III SUIM_assoc PF16619.5 CDJ66413.1 - 0.00095 19.2 5.0 0.0018 18.3 5.0 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Cytochrom_C550 PF14495.6 CDJ66413.1 - 0.049 13.3 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c-550 domain Spt20 PF12090.8 CDJ66413.1 - 0.1 12.2 8.8 0.13 11.8 8.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ66413.1 - 0.58 9.0 7.1 0.73 8.7 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MMtag PF10159.9 CDJ66413.1 - 1.2 9.5 4.5 3.9 7.8 4.5 1.8 1 1 0 1 1 1 0 Multiple myeloma tumor-associated 60KD_IMP PF02096.20 CDJ66413.1 - 2.2 8.2 4.9 3.1 7.7 4.9 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein SR-25 PF10500.9 CDJ66415.1 - 0.02 14.5 10.8 0.028 14.0 10.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ66415.1 - 0.86 9.5 6.4 1 9.2 6.4 1.1 1 0 0 1 1 1 0 SPX domain AF-4 PF05110.13 CDJ66415.1 - 2.5 6.1 13.2 3 5.8 13.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GP79 PF17463.2 CDJ66416.1 - 0.19 11.7 0.2 0.19 11.7 0.2 2.8 2 1 0 2 2 2 0 Gene product 79 Pex14_N PF04695.13 CDJ66419.1 - 0.79 10.4 14.7 0.99 10.0 14.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lin-8 PF03353.15 CDJ66419.1 - 1.7 8.1 7.3 1.8 8.0 7.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Tfb2 PF03849.14 CDJ66420.1 - 5.2e-15 55.3 0.0 7e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CDJ66420.1 - 8.9e-06 26.0 0.1 1.5e-05 25.3 0.1 1.5 1 1 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CDJ66420.1 - 0.0058 16.8 0.0 0.026 14.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1418 PF07214.12 CDJ66421.1 - 0.014 15.3 1.6 0.016 15.0 1.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) DUF4245 PF14030.6 CDJ66422.1 - 0.015 15.3 0.7 0.017 15.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) YebO PF13974.6 CDJ66422.1 - 0.24 11.5 5.8 0.38 10.9 5.8 1.3 1 0 0 1 1 1 0 YebO-like protein TFIIA PF03153.13 CDJ66422.1 - 3.3 7.6 11.4 3.7 7.5 11.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ66422.1 - 6 7.0 16.7 6 7.0 4.6 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SNARE_assoc PF09335.11 CDJ66423.1 - 0.13 12.7 0.4 0.33 11.5 0.4 1.6 1 1 0 1 1 1 0 SNARE associated Golgi protein Secretin_N_2 PF07655.13 CDJ66423.1 - 0.44 11.1 8.0 0.37 11.4 2.2 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain UCR_Fe-S_N PF10399.9 CDJ66423.1 - 1.3 8.4 6.6 3 7.2 0.1 2.6 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SUIM_assoc PF16619.5 CDJ66424.1 - 0.033 14.3 48.5 0.087 12.9 5.1 4.7 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 bMG10 PF17973.1 CDJ66424.1 - 0.071 13.3 1.9 0.19 11.9 1.9 1.7 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain SR-25 PF10500.9 CDJ66424.1 - 0.31 10.6 9.5 1.3 8.5 2.6 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ANAPC_CDC26 PF10471.9 CDJ66424.1 - 9.9 7.1 43.3 4.7 8.1 9.3 4.5 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit CDC26 DUF384 PF04064.13 CDJ66425.1 - 9.2e-10 38.2 0.1 2.3e-09 36.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF2828 PF11443.8 CDJ66425.1 - 0.00085 17.5 7.7 0.00085 17.5 7.7 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2828) DUF913 PF06025.12 CDJ66425.1 - 0.0016 17.5 0.8 0.0016 17.5 0.8 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) ANAPC_CDC26 PF10471.9 CDJ66425.1 - 0.005 17.7 43.9 0.035 15.0 13.5 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex APC subunit CDC26 TAF4 PF05236.14 CDJ66425.1 - 0.0069 16.2 17.0 0.066 13.0 6.2 2.4 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family SAPS PF04499.15 CDJ66425.1 - 0.066 12.0 7.6 0.012 14.5 3.5 1.7 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 CDJ66425.1 - 0.16 10.7 26.1 0.019 13.7 14.0 2.1 2 0 0 2 2 2 0 Presenilin SpoIIP PF07454.11 CDJ66425.1 - 0.27 10.6 14.6 0.25 10.8 4.4 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2992 PF11208.8 CDJ66425.1 - 0.49 10.7 0.1 0.49 10.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2992) Ribosomal_60s PF00428.19 CDJ66425.1 - 0.6 10.7 12.0 0.43 11.2 7.2 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Serinc PF03348.15 CDJ66425.1 - 1.9 7.3 7.8 3.9 6.3 7.8 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Thg1C PF14413.6 CDJ66425.1 - 2.1 8.5 11.4 7.7 6.7 0.1 2.6 2 0 0 2 2 2 0 Thg1 C terminal domain ALMT PF11744.8 CDJ66425.1 - 2.5 6.8 15.9 2.1 7.1 9.6 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF4638 PF15472.6 CDJ66425.1 - 3 7.5 11.2 0.55 9.9 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) SLC12 PF03522.15 CDJ66425.1 - 6.4 5.7 19.1 0.16 10.9 12.5 1.5 2 0 0 2 2 2 0 Solute carrier family 12 Sec16 PF12932.7 CDJ66425.1 - 7.2 7.2 7.5 4.7 7.8 0.5 2.9 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region WASH-7_C PF14746.6 CDJ66425.1 - 9.5 5.9 16.4 4.8 6.8 1.4 2.4 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal NINJA_B PF16136.5 CDJ66426.1 - 0.02 15.3 5.1 0.02 15.3 5.1 1.7 1 1 1 2 2 2 0 Putative nuclear localisation signal MRP-S25 PF13741.6 CDJ66426.1 - 0.034 13.7 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 SUIM_assoc PF16619.5 CDJ66426.1 - 0.32 11.1 6.6 0.44 10.6 6.6 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ66426.1 - 0.35 10.5 3.3 0.38 10.3 3.3 1.0 1 0 0 1 1 1 0 Spt20 family SseC PF04888.12 CDJ66426.1 - 1 8.9 24.4 1.4 8.5 24.4 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Sporozoite_P67 PF05642.11 CDJ66426.1 - 2.2 6.3 12.1 2.4 6.1 12.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sel1 PF08238.12 CDJ66427.1 - 2.8e-06 27.8 0.8 0.00013 22.5 0.3 2.9 2 0 0 2 2 2 1 Sel1 repeat HSP20 PF00011.21 CDJ66428.1 - 9.8e-11 41.7 0.0 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Ribosomal_60s PF00428.19 CDJ66428.1 - 0.0052 17.3 6.7 0.0052 17.3 6.7 1.6 2 0 0 2 2 2 1 60s Acidic ribosomal protein PepSY_2 PF13670.6 CDJ66428.1 - 0.12 12.4 4.5 0.17 11.9 4.5 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain ArsA_HSP20 PF17886.1 CDJ66428.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 HSP20-like domain found in ArsA SCO1-SenC PF02630.14 CDJ66429.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.0 1 0 0 1 1 1 0 SCO1/SenC MttA_Hcf106 PF02416.16 CDJ66429.1 - 0.48 9.8 2.6 0.54 9.6 2.2 1.3 1 1 0 1 1 1 0 mttA/Hcf106 family Topoisom_I_N PF02919.15 CDJ66430.1 - 0.11 12.0 5.8 0.24 10.9 5.8 1.5 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Vfa1 PF08432.10 CDJ66430.1 - 1.8 8.9 13.2 0.12 12.7 3.7 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SR-25 PF10500.9 CDJ66430.1 - 3.1 7.3 27.8 0.23 11.1 4.3 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Connexin PF00029.19 CDJ66430.1 - 5.8 6.6 4.8 0.91 9.2 1.2 1.5 2 0 0 2 2 2 0 Connexin Ferlin_C PF16165.5 CDJ66430.1 - 6.6 6.7 9.3 16 5.4 9.3 1.6 1 0 0 1 1 1 0 Ferlin C-terminus NPR3 PF03666.13 CDJ66430.1 - 6.8 5.4 11.6 0.14 11.0 4.3 1.7 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 TPT PF03151.16 CDJ66431.1 - 1e-68 231.8 8.0 1.3e-68 231.5 8.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CDJ66431.1 - 0.017 14.3 2.7 0.71 9.0 0.3 2.3 2 0 0 2 2 2 0 UAA transporter family EamA PF00892.20 CDJ66431.1 - 0.17 12.1 26.9 0.019 15.1 12.1 3.3 3 0 0 3 3 3 0 EamA-like transporter family Lin-8 PF03353.15 CDJ66432.1 - 0.09 12.3 22.4 0.16 11.5 22.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 CDJ66432.1 - 1.8 5.6 24.0 2.5 5.1 24.0 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CAP_C PF08603.11 CDJ66433.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal FKBP_C PF00254.28 CDJ66435.1 - 1.3e-22 79.9 0.0 2e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glucan_synthase PF02364.15 CDJ66437.1 - 1.9e-89 301.0 12.9 2.9e-58 197.8 10.8 4.2 2 2 2 4 4 4 4 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CDJ66437.1 - 2.3e-12 47.4 4.8 4.7e-10 39.9 4.8 2.6 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF5476 PF17570.2 CDJ66438.1 - 0.095 13.1 0.2 0.37 11.2 0.2 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5476) Rep_3 PF01051.21 CDJ66439.1 - 0.22 11.3 3.0 1 9.1 0.1 2.2 2 0 0 2 2 2 0 Initiator Replication protein Peptidase_C12 PF01088.21 CDJ66440.1 - 0.091 12.5 0.0 1.2 8.8 0.0 2.3 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 RskA PF10099.9 CDJ66441.1 - 3.5 7.9 52.0 0.041 14.2 5.9 4.2 2 1 2 4 4 4 0 Anti-sigma-K factor rskA CHORD PF04968.12 CDJ66442.1 - 2.1e-12 47.6 7.7 1.6e-08 35.2 0.3 2.5 2 0 0 2 2 2 2 CHORD AF-4 PF05110.13 CDJ66442.1 - 0.0028 15.9 17.7 0.0039 15.4 17.7 1.3 1 0 0 1 1 1 1 AF-4 proto-oncoprotein UPF0564 PF10595.9 CDJ66442.1 - 0.0075 15.4 6.1 0.0095 15.0 6.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 CCSAP PF15748.5 CDJ66442.1 - 0.2 11.8 18.9 0.29 11.3 18.9 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Utp14 PF04615.13 CDJ66442.1 - 0.23 10.0 12.9 0.28 9.7 12.9 1.0 1 0 0 1 1 1 0 Utp14 protein CDK5_activator PF03261.15 CDJ66442.1 - 0.3 10.6 4.2 0.38 10.2 4.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Apt1 PF10351.9 CDJ66442.1 - 2.7 6.7 8.1 3.5 6.4 8.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PPP4R2 PF09184.11 CDJ66442.1 - 5.4 6.5 7.7 7.5 6.0 7.7 1.1 1 0 0 1 1 1 0 PPP4R2 SOBP PF15279.6 CDJ66442.1 - 9.5 6.7 15.0 14 6.2 15.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2722 PF10846.8 CDJ66444.1 - 0.00033 19.7 9.5 0.00033 19.7 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ66444.1 - 0.00081 19.5 12.9 0.00081 19.5 12.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PepSY_TM PF03929.16 CDJ66444.1 - 0.045 13.4 1.8 0.051 13.2 1.8 1.1 1 0 0 1 1 1 0 PepSY-associated TM region MIF PF01187.18 CDJ66444.1 - 0.2 11.9 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Spt20 PF12090.8 CDJ66444.1 - 0.31 10.6 24.0 0.39 10.3 24.0 1.1 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 CDJ66444.1 - 0.65 8.6 4.1 0.6 8.7 4.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TERB2 PF15101.6 CDJ66444.1 - 1.1 9.2 9.4 1.2 9.1 9.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Suf PF05843.14 CDJ66444.1 - 1.4 8.8 10.2 1.5 8.7 10.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0560 PF10577.9 CDJ66444.1 - 1.8 7.0 11.1 2 6.8 11.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Presenilin PF01080.17 CDJ66444.1 - 2.4 6.8 6.7 2.5 6.8 6.7 1.1 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.8 CDJ66444.1 - 2.6 7.8 5.5 3.2 7.5 5.5 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Roughex PF06020.11 CDJ66444.1 - 4.8 6.2 11.6 5.7 5.9 11.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PAM2 PF07145.15 CDJ66445.1 - 0.042 13.5 2.1 0.09 12.5 2.1 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region TFIIA PF03153.13 CDJ66446.1 - 1.2 9.1 11.9 1.3 9.0 11.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ66447.1 - 0.00016 22.0 6.8 0.00016 22.0 6.8 11.0 2 2 5 8 8 8 1 Anti-sigma-K factor rskA RRM_1 PF00076.22 CDJ66449.1 - 0.00074 19.3 0.0 0.54 10.1 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dehydrin PF00257.19 CDJ66449.1 - 0.0011 19.6 2.8 0.0011 19.6 2.8 2.3 2 0 0 2 2 2 1 Dehydrin SR-25 PF10500.9 CDJ66449.1 - 0.0022 17.6 9.4 0.0022 17.6 9.4 2.4 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF2407_C PF13373.6 CDJ66449.1 - 0.004 17.3 4.1 0.015 15.5 0.0 2.2 2 0 0 2 2 2 1 DUF2407 C-terminal domain Herpes_pp85 PF04637.12 CDJ66449.1 - 0.12 10.7 2.6 0.19 10.1 2.6 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) AAA_11 PF13086.6 CDJ66449.1 - 1.3 8.7 15.5 0.98 9.1 11.0 2.0 2 0 0 2 2 2 0 AAA domain NST1 PF13945.6 CDJ66449.1 - 2.9 8.0 21.9 0.47 10.5 0.8 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator RskA PF10099.9 CDJ66449.1 - 2.9 8.1 27.8 7.1 6.9 20.1 2.5 2 1 0 2 2 2 0 Anti-sigma-K factor rskA DUF1980 PF09323.10 CDJ66449.1 - 2.9 7.8 6.7 3.5 7.5 4.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DDE_Tnp_1_2 PF13586.6 CDJ66449.1 - 3.4 8.1 16.1 2.2 8.7 6.3 2.8 2 1 1 3 3 3 0 Transposase DDE domain Connexin PF00029.19 CDJ66449.1 - 4.1 7.1 11.7 9.8 5.9 8.5 2.1 2 0 0 2 2 2 0 Connexin Pap_E4 PF02711.14 CDJ66449.1 - 5.7 8.0 12.5 7.4 7.6 0.1 2.4 2 0 0 2 2 2 0 E4 protein PP2C PF00481.21 CDJ66452.1 - 3.5e-18 66.2 1.9 3.5e-18 66.2 1.9 4.3 2 2 1 4 4 4 2 Protein phosphatase 2C SR-25 PF10500.9 CDJ66452.1 - 3.7e-06 26.7 17.6 3.7e-06 26.7 17.6 7.6 3 1 4 7 7 7 3 Nuclear RNA-splicing-associated protein SurA_N_2 PF13623.6 CDJ66452.1 - 0.012 15.5 6.9 0.012 15.5 6.9 3.2 3 0 0 3 3 3 0 SurA N-terminal domain DTHCT PF08070.11 CDJ66452.1 - 0.026 15.3 7.8 0.026 15.3 7.8 6.7 4 2 3 7 7 7 0 DTHCT (NUC029) region AAA_23 PF13476.6 CDJ66452.1 - 0.026 15.0 0.5 0.026 15.0 0.5 2.7 2 1 0 2 2 2 0 AAA domain RskA PF10099.9 CDJ66452.1 - 0.091 13.1 38.5 0.26 11.5 13.2 4.1 3 2 0 3 3 3 0 Anti-sigma-K factor rskA DUF2681 PF10883.8 CDJ66452.1 - 2.3 8.7 33.2 3.1 8.2 0.5 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Ribosomal_60s PF00428.19 CDJ66454.1 - 0.54 10.9 7.7 0.71 10.5 7.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein CreD PF06123.12 CDJ66455.1 - 0.0021 16.9 0.1 0.0021 16.9 0.1 1.5 2 0 0 2 2 2 1 Inner membrane protein CreD SPX PF03105.19 CDJ66455.1 - 0.019 14.9 12.1 0.024 14.6 12.1 1.1 1 0 0 1 1 1 0 SPX domain UPF0697 PF15117.6 CDJ66455.1 - 0.071 13.2 0.1 0.071 13.2 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0697 CcmF_C PF16327.5 CDJ66455.1 - 1.1 8.5 8.2 0.13 11.6 0.9 2.2 2 0 0 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal Nha1_C PF08619.10 CDJ66455.1 - 1.4 8.1 19.9 0.027 13.7 3.4 2.0 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Pex14_N PF04695.13 CDJ66455.1 - 2.3 8.8 25.4 1.2 9.8 10.0 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3464 PF11947.8 CDJ66455.1 - 3.1 7.5 14.0 1.4 8.7 2.6 2.7 2 1 0 2 2 2 0 Photosynthesis affected mutant 68 SUIM_assoc PF16619.5 CDJ66455.1 - 4.4 7.5 50.2 1.3 9.2 5.0 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF4647 PF15504.6 CDJ66455.1 - 6.4 5.8 21.5 0.27 10.3 6.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) BAF1_ABF1 PF04684.13 CDJ66455.1 - 8 5.4 23.5 0.17 10.9 3.2 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor HEAT PF02985.22 CDJ66456.1 - 1.5e-06 27.9 11.4 0.0097 16.1 0.1 4.8 4 0 0 4 4 4 2 HEAT repeat Apt1 PF10351.9 CDJ66456.1 - 0.2 10.5 12.8 4 6.2 0.0 2.5 2 1 0 2 2 2 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 CDJ66456.1 - 2.4 7.5 10.1 61 2.9 10.5 2.3 2 1 0 2 2 2 0 Plasmodium vivax Vir protein Peroxin-3 PF04882.12 CDJ66456.1 - 4 6.3 0.0 4 6.3 0.0 3.1 2 2 0 2 2 2 0 Peroxin-3 Aminotran_1_2 PF00155.21 CDJ66457.1 - 5.5e-07 29.1 0.0 5.5e-07 29.1 0.0 2.5 2 1 0 2 2 1 1 Aminotransferase class I and II Activator_LAG-3 PF11498.8 CDJ66457.1 - 1.2e-05 24.6 44.6 1.4e-05 24.3 44.6 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ66457.1 - 0.00068 19.8 31.7 0.00076 19.6 31.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PIEZO PF15917.5 CDJ66457.1 - 0.032 13.7 14.3 0.045 13.2 14.3 1.2 1 0 0 1 1 1 0 Piezo AbLIM_anchor PF16182.5 CDJ66457.1 - 0.034 14.0 5.2 0.039 13.8 5.2 1.1 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM IHABP4_N PF16174.5 CDJ66457.1 - 0.034 14.8 15.6 0.057 14.0 15.6 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal V_ATPase_I PF01496.19 CDJ66457.1 - 0.039 11.9 14.3 0.046 11.7 14.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CRT10 PF08728.10 CDJ66457.1 - 0.05 11.8 2.5 0.057 11.6 2.5 1.0 1 0 0 1 1 1 0 CRT10 YabA PF06156.13 CDJ66457.1 - 0.061 14.0 15.5 0.096 13.3 15.5 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 CDJ66457.1 - 0.35 10.4 23.1 0.47 10.0 23.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HemX PF04375.14 CDJ66457.1 - 0.52 9.5 39.9 0.76 9.0 39.9 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase OmpH PF03938.14 CDJ66457.1 - 0.56 10.5 39.5 1.1 9.6 39.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_60s PF00428.19 CDJ66457.1 - 0.56 10.8 14.2 0.08 13.5 9.7 1.9 3 0 0 3 3 1 0 60s Acidic ribosomal protein ALMT PF11744.8 CDJ66457.1 - 0.8 8.5 7.4 0.89 8.3 7.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FapA PF03961.13 CDJ66457.1 - 0.81 8.2 9.8 0.95 8.0 9.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PAT1 PF09770.9 CDJ66457.1 - 0.81 7.9 26.4 0.95 7.7 26.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.6 CDJ66457.1 - 0.82 8.0 2.9 1.1 7.6 2.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.10 CDJ66457.1 - 0.92 9.6 14.3 1.3 9.1 14.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Suf PF05843.14 CDJ66457.1 - 0.97 9.4 15.7 1.5 8.8 15.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM222A PF15258.6 CDJ66457.1 - 1 8.4 28.6 1.4 8.0 28.6 1.1 1 0 0 1 1 1 0 Protein family of FAM222A TALPID3 PF15324.6 CDJ66457.1 - 1.1 6.9 30.9 1.3 6.6 30.9 1.0 1 0 0 1 1 1 0 Hedgehog signalling target DUF4179 PF13786.6 CDJ66457.1 - 1.2 9.6 7.6 2.8 8.5 7.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) MMR1 PF08505.10 CDJ66457.1 - 1.3 9.3 12.9 1.9 8.7 12.9 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SAE2 PF08573.10 CDJ66457.1 - 3.4 8.8 11.7 7.2 7.8 11.7 1.6 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus FAM60A PF15396.6 CDJ66457.1 - 4.4 7.3 8.2 5.7 6.9 8.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Glyco_transf_41 PF13844.6 CDJ66457.1 - 5.9 5.2 7.8 7.7 4.8 7.8 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 LMBR1 PF04791.16 CDJ66457.1 - 6 5.7 7.0 6.5 5.5 7.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.12 CDJ66457.1 - 6.2 5.2 20.6 7 5.0 20.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Neur_chan_memb PF02932.16 CDJ66457.1 - 7.9 6.5 9.5 10 6.1 9.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SF3a60_bindingd PF12108.8 CDJ66458.1 - 1.4e-05 24.8 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain RskA PF10099.9 CDJ66458.1 - 0.0077 16.6 3.1 0.011 16.0 3.1 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA RskA PF10099.9 CDJ66459.1 - 0.005 17.1 14.9 0.024 14.9 14.8 2.0 1 1 0 1 1 1 1 Anti-sigma-K factor rskA RIFIN PF02009.16 CDJ66459.1 - 0.1 12.5 5.4 0.12 12.2 5.4 1.1 1 0 0 1 1 1 0 Rifin HEV_ORF1 PF02444.16 CDJ66459.1 - 0.15 12.6 3.6 0.32 11.5 3.6 1.7 1 1 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) SR-25 PF10500.9 CDJ66459.1 - 0.23 11.0 11.1 0.38 10.3 11.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ66459.1 - 1.5 8.8 25.4 1.8 8.4 25.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ66459.1 - 2.3 6.7 11.5 2.8 6.4 11.5 1.1 1 0 0 1 1 1 0 Macoilin family IMUP PF15761.5 CDJ66459.1 - 5.4 7.8 14.8 1.6 9.4 10.9 2.1 1 1 1 2 2 2 0 Immortalisation up-regulated protein Hid1 PF12722.7 CDJ66459.1 - 9.5 4.2 11.6 11 4.0 11.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Proteasom_PSMB PF10508.9 CDJ66460.1 - 3.5e-12 45.6 4.5 1.1e-06 27.5 3.8 2.1 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit SAPS PF04499.15 CDJ66460.1 - 0.15 10.8 0.1 0.28 9.9 0.1 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CCER1 PF15482.6 CDJ66461.1 - 0.0035 17.3 1.2 0.0086 16.0 1.2 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing glutamate-rich protein family 1 Corona_S2 PF01601.16 CDJ66461.1 - 0.41 9.1 2.7 0.56 8.6 2.7 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Lin-8 PF03353.15 CDJ66461.1 - 3 7.3 6.8 0.35 10.4 2.4 1.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Peptidase_M16_C PF05193.21 CDJ66462.1 - 2.9e-33 115.4 0.0 6.6e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDJ66462.1 - 6.7e-25 87.8 0.0 2.4e-24 86.0 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) PIGA PF08288.12 CDJ66462.1 - 0.075 13.6 0.0 1.8 9.2 0.0 2.5 2 0 0 2 2 2 0 PIGA (GPI anchor biosynthesis) Jiraiya PF15038.6 CDJ66463.1 - 0.0001 21.8 2.0 0.00013 21.5 2.0 1.2 1 0 0 1 1 1 1 Jiraiya SLH PF00395.20 CDJ66463.1 - 0.095 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 S-layer homology domain Orai-1 PF07856.12 CDJ66463.1 - 0.18 11.5 10.1 2 8.1 0.1 2.2 2 0 0 2 2 2 0 Mediator of CRAC channel activity TMEM171 PF15471.6 CDJ66463.1 - 0.31 10.0 1.3 0.44 9.5 1.3 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 PIG-P PF08510.12 CDJ66463.1 - 1.7 8.6 0.0 1.7 8.6 0.0 2.9 2 2 0 2 2 2 0 PIG-P MFS_1 PF07690.16 CDJ66464.1 - 1.3e-20 73.7 36.5 9.2e-19 67.6 5.3 3.9 4 1 1 5 5 5 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ66464.1 - 1.7e-11 43.6 1.0 1.7e-11 43.6 1.0 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 CDJ66464.1 - 6.6e-07 28.0 24.8 0.0041 15.5 4.9 5.2 4 1 1 5 5 5 4 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.13 CDJ66464.1 - 0.0046 17.0 20.8 0.0046 17.0 20.8 3.0 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ66464.1 - 0.56 8.7 6.8 0.023 13.3 0.6 1.8 2 0 0 2 2 2 0 Macoilin family eIF-3_zeta PF05091.12 CDJ66464.1 - 0.97 8.3 5.7 2 7.3 5.7 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4128 PF13554.6 CDJ66465.1 - 0.088 12.9 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function AP2 PF00847.20 CDJ66466.1 - 2e-19 69.6 1.2 1.8e-09 37.6 0.1 6.0 7 0 0 7 7 7 3 AP2 domain DUF2515 PF10720.9 CDJ66466.1 - 0.31 10.2 6.5 0.6 9.2 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) WD40 PF00400.32 CDJ66467.1 - 0.37 11.7 3.4 16 6.6 0.0 4.7 4 0 0 4 4 4 0 WD domain, G-beta repeat TGT PF01702.18 CDJ66468.1 - 2.9e-09 36.6 0.1 8.9e-09 35.0 0.1 1.7 2 0 0 2 2 2 1 Queuine tRNA-ribosyltransferase SUIM_assoc PF16619.5 CDJ66468.1 - 0.15 12.1 0.0 0.15 12.1 0.0 9.5 8 3 0 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 SID-1_RNA_chan PF13965.6 CDJ66468.1 - 0.99 7.7 2.8 1.9 6.8 2.8 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ribosomal_L7Ae PF01248.26 CDJ66469.1 - 2.2e-25 88.2 0.3 2.9e-25 87.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CDJ66469.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CDJ66469.1 - 0.065 13.3 0.0 0.073 13.1 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 DUF1631 PF07793.11 CDJ66470.1 - 0.0012 17.4 12.8 0.0012 17.4 12.8 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1631) SUIM_assoc PF16619.5 CDJ66470.1 - 0.017 15.2 5.2 0.038 14.0 5.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 YajC PF02699.15 CDJ66470.1 - 0.83 9.6 4.0 2.1 8.3 4.0 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit Spt20 PF12090.8 CDJ66470.1 - 1.5 8.4 8.7 2.4 7.7 8.7 1.2 1 0 0 1 1 1 0 Spt20 family PDEase_I PF00233.19 CDJ66472.1 - 1.8e-49 168.6 6.2 1.8e-49 168.6 6.2 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DUF2722 PF10846.8 CDJ66472.1 - 0.0003 19.9 5.8 0.0004 19.5 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ66472.1 - 0.012 15.7 15.5 0.018 15.1 15.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ66472.1 - 0.12 10.2 1.4 0.17 9.8 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Suf PF05843.14 CDJ66472.1 - 0.18 11.7 4.4 0.27 11.2 4.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Band_3_cyto PF07565.13 CDJ66472.1 - 0.22 11.3 2.2 0.46 10.2 2.2 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex14_N PF04695.13 CDJ66472.1 - 0.24 12.0 7.5 0.44 11.2 7.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Type_III_YscX PF09474.10 CDJ66472.1 - 0.64 10.3 5.9 1.6 9.0 5.9 1.7 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) DUF4834 PF16118.5 CDJ66472.1 - 2 9.4 5.3 4.8 8.2 5.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Activator_LAG-3 PF11498.8 CDJ66472.1 - 5.4 5.9 29.9 10 5.0 29.9 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SR-25 PF10500.9 CDJ66473.1 - 0.09 12.4 26.0 0.017 14.7 21.5 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.16 CDJ66473.1 - 0.12 12.4 4.7 0.15 12.1 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lin-8 PF03353.15 CDJ66473.1 - 0.94 9.0 9.1 0.51 9.8 7.1 1.5 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ66473.1 - 1.9 8.3 16.4 2.3 8.1 16.4 1.2 1 0 0 1 1 1 0 SPX domain ABC2_membrane_2 PF12679.7 CDJ66473.1 - 3.3 6.9 6.5 4.8 6.4 6.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Trypan_PARP PF05887.11 CDJ66474.1 - 0.13 12.3 15.7 0.073 13.1 13.2 1.9 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ketoacyl-synt PF00109.26 CDJ66475.1 - 2e-73 247.1 0.1 1.1e-72 244.7 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 CDJ66475.1 - 3.7e-63 212.7 0.1 1.2e-51 175.2 0.0 3.0 3 0 0 3 3 3 2 KR domain Acyl_transf_1 PF00698.21 CDJ66475.1 - 2.2e-45 155.5 0.0 4.9e-45 154.4 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 CDJ66475.1 - 7.5e-43 146.9 0.8 1.2e-42 146.2 0.8 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CDJ66475.1 - 4e-39 133.3 0.6 1.1e-38 131.8 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 CDJ66475.1 - 2.6e-16 59.8 0.0 7.6e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 CDJ66475.1 - 1e-13 51.4 0.0 2.4e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 CDJ66475.1 - 3.3e-11 43.0 3.4 4.2e-08 32.9 0.0 3.5 4 0 0 4 4 4 2 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 CDJ66475.1 - 6.4e-11 43.4 0.0 4.1e-10 40.8 0.0 2.6 2 0 0 2 2 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 CDJ66475.1 - 3.3e-08 33.4 0.1 1.1e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KAsynt_C_assoc PF16197.5 CDJ66475.1 - 1e-06 29.1 0.1 3.7e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 CDJ66475.1 - 9.7e-06 25.4 4.0 7.7e-05 22.5 0.2 3.4 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 CDJ66475.1 - 0.00042 19.8 0.0 0.0014 18.1 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 CDJ66475.1 - 0.49 10.3 2.5 5.5 6.9 0.3 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MitMem_reg PF13012.6 CDJ66476.1 - 6.2e-19 68.5 13.5 6.2e-19 68.5 13.5 2.8 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function Isy1 PF06246.12 CDJ66476.1 - 0.0016 18.1 27.8 0.034 13.7 9.7 2.2 2 0 0 2 2 2 2 Isy1-like splicing family Pinin_SDK_memA PF04696.13 CDJ66476.1 - 0.012 15.6 23.5 0.012 15.6 23.5 3.2 3 0 0 3 3 3 0 pinin/SDK/memA/ protein conserved region CCSAP PF15748.5 CDJ66476.1 - 0.18 12.0 36.1 0.082 13.1 11.2 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Spore_coat_CotO PF14153.6 CDJ66476.1 - 0.25 11.3 51.8 0.46 10.4 18.8 2.2 2 0 0 2 2 2 0 Spore coat protein CotO DUF5327 PF17261.2 CDJ66476.1 - 0.39 11.5 48.1 2.8 8.7 20.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5327) FAM60A PF15396.6 CDJ66476.1 - 0.4 10.6 32.8 0.13 12.3 8.2 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Presenilin PF01080.17 CDJ66476.1 - 0.44 9.3 43.4 0.32 9.7 16.1 2.1 2 0 0 2 2 2 0 Presenilin TCP PF03634.13 CDJ66476.1 - 0.5 10.9 31.8 2.6 8.6 13.1 2.4 2 0 0 2 2 2 0 TCP family transcription factor Med15 PF09606.10 CDJ66476.1 - 0.53 8.9 66.7 0.007 15.1 28.6 2.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4045 PF13254.6 CDJ66476.1 - 0.6 9.7 30.7 0.27 10.9 8.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF3801 PF12687.7 CDJ66476.1 - 0.7 9.9 32.7 2 8.5 10.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Neur_chan_memb PF02932.16 CDJ66476.1 - 0.86 9.6 30.4 0.17 11.9 10.3 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ66476.1 - 1.9 8.2 32.7 0.21 11.4 10.3 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Endostatin PF06482.11 CDJ66476.1 - 1.9 7.8 31.6 0.26 10.7 10.4 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Serinc PF03348.15 CDJ66476.1 - 2 7.2 22.5 0.83 8.5 8.2 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) EOS1 PF12326.8 CDJ66476.1 - 3.5 7.5 21.1 3 7.7 6.8 2.4 2 0 0 2 2 2 0 N-glycosylation protein DUF2052 PF09747.9 CDJ66476.1 - 3.6 7.7 40.0 3.9 7.6 14.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 CDJ66476.1 - 4 5.6 32.7 0.16 10.2 9.8 2.1 2 0 0 2 2 2 0 CDC45-like protein Paf1 PF03985.13 CDJ66476.1 - 4.4 6.2 41.4 0.16 10.9 13.6 2.3 2 0 0 2 2 2 0 Paf1 CLN3 PF02487.17 CDJ66476.1 - 4.5 6.2 29.6 1 8.3 12.4 2.3 2 0 0 2 2 2 0 CLN3 protein DUF1387 PF07139.11 CDJ66476.1 - 4.6 6.9 36.4 1 9.0 12.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) DUF3807 PF12720.7 CDJ66476.1 - 5.7 7.2 51.7 0.63 10.3 18.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) COX14 PF14880.6 CDJ66476.1 - 6.8 6.6 0.0 6.8 6.6 0.0 5.4 3 2 0 3 3 1 0 Cytochrome oxidase c assembly CSG2 PF16965.5 CDJ66476.1 - 7.7 5.3 22.6 1.6 7.6 8.1 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator Lin-8 PF03353.15 CDJ66476.1 - 8.4 5.8 42.8 0.43 10.1 17.6 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 CDJ66476.1 - 8.9 5.2 37.1 0.54 9.2 13.0 2.1 2 0 0 2 2 2 0 Solute carrier family 12 HCO3_cotransp PF00955.21 CDJ66476.1 - 9.9 4.8 16.9 2 7.2 4.6 2.1 2 0 0 2 2 2 0 HCO3- transporter family HSP70 PF00012.20 CDJ66477.1 - 3.4e-21 75.1 0.2 1.9e-20 72.6 0.0 1.9 1 1 1 2 2 2 1 Hsp70 protein Med15 PF09606.10 CDJ66477.1 - 0.0095 14.7 8.0 0.012 14.4 8.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF5421 PF17458.2 CDJ66477.1 - 0.013 14.9 2.2 0.016 14.6 2.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) DUF2722 PF10846.8 CDJ66477.1 - 0.038 13.0 8.6 0.051 12.5 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4064 PF13273.6 CDJ66477.1 - 0.043 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Med3 PF11593.8 CDJ66477.1 - 0.13 11.4 8.6 0.21 10.8 8.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4834 PF16118.5 CDJ66477.1 - 0.16 13.0 1.2 0.27 12.2 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ66477.1 - 0.24 11.0 15.2 0.4 10.2 15.2 1.3 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ66477.1 - 0.95 8.4 16.6 1.4 7.8 16.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4179 PF13786.6 CDJ66477.1 - 4.3 7.9 5.3 4.4 7.8 0.3 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4179) RskA PF10099.9 CDJ66478.1 - 3.3e-07 30.8 36.3 0.00019 21.8 7.8 3.3 2 1 1 3 3 3 2 Anti-sigma-K factor rskA CTP_transf_1 PF01148.20 CDJ66478.1 - 4.3e-06 26.7 0.9 7e-06 26.0 0.9 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family DUF4834 PF16118.5 CDJ66478.1 - 0.00048 21.0 3.2 0.00048 21.0 3.2 4.9 3 1 0 3 3 2 1 Domain of unknown function (DUF4834) CD20 PF04103.15 CDJ66478.1 - 0.0081 16.3 2.4 0.72 9.9 0.2 2.9 2 1 0 2 2 2 1 CD20-like family FA_desaturase PF00487.24 CDJ66478.1 - 0.032 14.1 2.3 0.16 11.8 1.5 2.1 2 0 0 2 2 2 0 Fatty acid desaturase 7tm_1 PF00001.21 CDJ66478.1 - 0.066 12.5 0.1 0.066 12.5 0.1 2.3 2 1 1 3 3 2 0 7 transmembrane receptor (rhodopsin family) OAD_gamma PF04277.13 CDJ66478.1 - 0.25 12.0 0.0 0.25 12.0 0.0 4.6 5 0 0 5 5 5 0 Oxaloacetate decarboxylase, gamma chain FHIPEP PF00771.20 CDJ66478.1 - 0.33 9.3 9.7 0.033 12.7 1.6 2.2 2 0 0 2 2 2 0 FHIPEP family SID-1_RNA_chan PF13965.6 CDJ66478.1 - 0.58 8.5 5.1 2 6.7 0.4 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Dpy19 PF10034.9 CDJ66478.1 - 1.3 7.1 5.7 0.44 8.7 1.8 1.8 2 0 0 2 2 2 0 Q-cell neuroblast polarisation FPN1 PF06963.12 CDJ66478.1 - 2.4 6.6 7.3 0.24 9.9 0.4 2.3 2 0 0 2 2 2 0 Ferroportin1 (FPN1) YfhO PF09586.10 CDJ66478.1 - 2.5 6.2 7.5 0.25 9.6 1.3 1.9 2 0 0 2 2 2 0 Bacterial membrane protein YfhO EMC3_TMCO1 PF01956.16 CDJ66478.1 - 7 6.3 13.9 0.4 10.4 1.3 2.7 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like RskA PF10099.9 CDJ66479.1 - 0.0002 21.7 21.3 0.007 16.7 4.4 2.0 1 1 1 2 2 2 2 Anti-sigma-K factor rskA DUF4598 PF15370.6 CDJ66479.1 - 0.011 16.2 1.9 0.011 16.2 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) PIP5K PF01504.18 CDJ66479.1 - 0.025 13.8 6.1 0.026 13.8 6.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF4179 PF13786.6 CDJ66479.1 - 0.047 14.2 0.3 0.65 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF4834 PF16118.5 CDJ66479.1 - 0.21 12.5 26.9 1.8 9.6 6.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) SDF PF00375.18 CDJ66479.1 - 0.98 8.4 2.5 2.6 7.0 0.1 1.9 1 1 1 2 2 2 0 Sodium:dicarboxylate symporter family Presenilin PF01080.17 CDJ66479.1 - 0.98 8.1 16.2 1.1 7.9 16.2 1.1 1 0 0 1 1 1 0 Presenilin Porph_ging PF09697.10 CDJ66479.1 - 1.5 9.4 8.0 0.9 10.1 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) ANAPC_CDC26 PF10471.9 CDJ66479.1 - 2 9.3 44.5 0.078 13.8 18.6 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 COX16 PF14138.6 CDJ66479.1 - 3.8 8.1 8.2 9.2 6.9 0.5 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 MAT1 PF06391.13 CDJ66479.1 - 6.1 6.6 25.8 8.7 6.1 25.8 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Rpp20 PF12328.8 CDJ66479.1 - 6.3 6.8 14.7 0.8 9.7 3.3 2.1 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P FHIPEP PF00771.20 CDJ66479.1 - 6.3 5.1 16.0 0.35 9.3 4.1 2.0 1 1 1 2 2 2 0 FHIPEP family eIF_4EBP PF05456.11 CDJ66479.1 - 6.9 6.6 13.3 2.6 8.0 5.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) TUSC2 PF15000.6 CDJ66479.1 - 7.8 6.8 10.7 0.76 10.1 2.3 2.1 2 0 0 2 2 2 0 Tumour suppressor candidate 2 RAB3GAP2_N PF14655.6 CDJ66479.1 - 9.9 5.3 25.2 1.4 8.1 9.5 2.1 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SR-25 PF10500.9 CDJ66480.1 - 0.019 14.6 6.0 0.032 13.9 6.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ66480.1 - 0.15 12.8 3.9 0.32 11.7 3.9 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein RskA PF10099.9 CDJ66481.1 - 0.0081 16.5 12.8 0.0081 16.5 12.8 7.1 2 2 2 4 4 4 1 Anti-sigma-K factor rskA N6_N4_Mtase PF01555.18 CDJ66481.1 - 0.017 14.9 5.4 7 6.3 5.4 3.1 1 1 0 1 1 1 0 DNA methylase Fer2 PF00111.27 CDJ66482.1 - 5.8e-20 71.0 1.6 1.7e-19 69.6 1.6 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 CDJ66482.1 - 0.0088 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TFIIA PF03153.13 CDJ66482.1 - 0.24 11.4 25.8 0.35 10.8 25.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_UL32 PF06070.11 CDJ66482.1 - 0.48 8.1 5.0 0.56 7.9 5.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 PAT1 PF09770.9 CDJ66482.1 - 8.6 4.5 17.2 11 4.2 17.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ICAP-1_inte_bdg PF10480.9 CDJ66483.1 - 0.0086 16.1 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 Beta-1 integrin binding protein PfaD_N PF18328.1 CDJ66483.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.6 1 1 0 1 1 1 0 Fatty acid synthase subunit PfaD N-terminal domain LpxI_N PF17930.1 CDJ66483.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 LpxI N-terminal domain DUF3446 PF11928.8 CDJ66484.1 - 0.028 14.7 8.0 0.028 14.7 8.0 2.1 3 0 0 3 3 3 0 Early growth response N-terminal domain DUF2207 PF09972.9 CDJ66484.1 - 0.066 12.0 0.0 0.086 11.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Spt20 PF12090.8 CDJ66484.1 - 0.07 12.7 0.7 0.1 12.2 0.7 1.3 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ66484.1 - 0.13 12.6 10.2 0.2 12.0 10.2 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA IMUP PF15761.5 CDJ66484.1 - 7 7.4 13.4 0.56 10.9 7.6 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein YajC PF02699.15 CDJ66484.1 - 9.9 6.1 6.8 7.7 6.5 1.5 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit ATP_bind_1 PF03029.17 CDJ66486.1 - 6.2e-10 39.3 0.0 0.00096 19.0 0.0 2.2 1 1 0 2 2 2 2 Conserved hypothetical ATP binding protein DUF4834 PF16118.5 CDJ66487.1 - 0.0025 18.7 1.0 0.0042 18.0 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) RskA PF10099.9 CDJ66487.1 - 0.0035 17.6 16.8 0.0054 17.1 13.0 2.0 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Ureide_permease PF07168.11 CDJ66487.1 - 0.018 13.8 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Ureide permease FAM176 PF14851.6 CDJ66487.1 - 0.02 14.6 0.1 0.029 14.0 0.1 1.2 1 0 0 1 1 1 0 FAM176 family EphA2_TM PF14575.6 CDJ66487.1 - 0.022 15.7 0.3 0.053 14.4 0.3 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 CDJ66487.1 - 0.048 13.5 4.7 0.084 12.7 4.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 FHIPEP PF00771.20 CDJ66487.1 - 0.049 12.1 0.3 0.066 11.7 0.3 1.1 1 0 0 1 1 1 0 FHIPEP family DUF3357 PF11837.8 CDJ66487.1 - 0.065 13.7 1.3 0.6 10.6 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) OSTbeta PF15048.6 CDJ66487.1 - 0.066 13.3 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein ASFV_J13L PF05568.11 CDJ66487.1 - 0.16 11.7 3.5 0.71 9.6 1.4 2.1 2 0 0 2 2 2 0 African swine fever virus J13L protein AcrZ PF10766.9 CDJ66487.1 - 0.18 11.4 0.3 0.18 11.4 0.3 1.6 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ TMEM208_SND2 PF05620.11 CDJ66487.1 - 0.69 9.7 3.2 1.1 9.0 3.2 1.4 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 LapA_dom PF06305.11 CDJ66487.1 - 6.7 6.6 13.8 44 4.0 9.7 3.0 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2722 PF10846.8 CDJ66487.1 - 9.7 5.0 13.7 13 4.6 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ66488.1 - 0.0018 19.2 3.6 0.0018 19.2 3.6 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4834) YfhO PF09586.10 CDJ66488.1 - 0.0044 15.3 0.7 0.0071 14.6 0.7 1.2 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF4820 PF16091.5 CDJ66488.1 - 0.014 14.7 1.0 0.014 14.7 1.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4820) SID-1_RNA_chan PF13965.6 CDJ66488.1 - 0.051 12.0 0.0 0.1 11.0 0.0 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CotH PF08757.11 CDJ66488.1 - 0.29 10.6 5.4 0.13 11.8 1.9 1.9 2 0 0 2 2 2 0 CotH kinase protein DUF4131 PF13567.6 CDJ66488.1 - 0.55 9.9 7.6 0.25 11.0 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ATG22 PF11700.8 CDJ66488.1 - 0.7 8.4 2.9 1.6 7.3 2.9 1.5 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like KASH PF10541.9 CDJ66488.1 - 1 9.7 24.6 2.6 8.4 11.8 2.5 2 0 0 2 2 2 0 Nuclear envelope localisation domain ABC2_membrane_2 PF12679.7 CDJ66488.1 - 1.7 7.8 5.2 4.2 6.6 5.2 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2722 PF10846.8 CDJ66488.1 - 2.1 7.2 44.2 0.032 13.2 15.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) MRAP PF15183.6 CDJ66488.1 - 2.5 8.1 4.5 21 5.1 0.3 2.9 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family TLD PF07534.16 CDJ66489.1 - 6.6e-27 94.4 0.3 1.3e-26 93.5 0.3 1.5 1 0 0 1 1 1 1 TLD DUF2722 PF10846.8 CDJ66489.1 - 0.00049 19.2 9.8 0.00049 19.2 9.8 5.9 4 1 1 6 6 6 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ66490.1 - 0.18 12.1 42.1 3 8.1 18.5 2.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA AAA_23 PF13476.6 CDJ66490.1 - 3.4 8.1 31.9 5.5 7.4 16.6 2.3 2 0 0 2 2 2 0 AAA domain TGS PF02824.21 CDJ66491.1 - 6.9e-15 54.8 0.0 8.9e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 TGS domain MMR_HSR1_Xtn PF16897.5 CDJ66491.1 - 3.9e-06 26.8 0.0 6.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AARP2CN PF08142.12 CDJ66492.1 - 5.5e-20 71.3 4.3 5.5e-20 71.3 4.3 3.8 2 2 0 2 2 1 1 AARP2CN (NUC121) domain PRCC PF10253.9 CDJ66492.1 - 2.7e-06 28.3 48.6 0.00015 22.7 6.6 2.3 2 0 0 2 2 2 2 Mitotic checkpoint regulator, MAD2B-interacting SpoIIIAH PF12685.7 CDJ66492.1 - 6e-06 26.2 22.4 0.00093 19.1 2.9 2.3 2 0 0 2 2 2 2 SpoIIIAH-like protein SAPS PF04499.15 CDJ66492.1 - 1.2e-05 24.3 16.1 0.0024 16.7 2.3 2.1 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein SR-25 PF10500.9 CDJ66492.1 - 2.9e-05 23.8 17.5 2.9e-05 23.8 17.5 2.9 3 1 0 3 3 1 1 Nuclear RNA-splicing-associated protein GTP_EFTU PF00009.27 CDJ66492.1 - 3.1e-05 23.6 7.8 3.1e-05 23.6 7.8 3.0 2 2 0 2 2 1 1 Elongation factor Tu GTP binding domain AF-4 PF05110.13 CDJ66492.1 - 4.1e-05 21.9 57.2 9.2e-05 20.8 28.3 2.2 2 0 0 2 2 2 2 AF-4 proto-oncoprotein Presenilin PF01080.17 CDJ66492.1 - 6e-05 22.0 45.7 0.016 14.0 20.7 2.2 2 0 0 2 2 2 2 Presenilin SDA1 PF05285.12 CDJ66492.1 - 0.00018 21.1 3.8 0.00018 21.1 3.8 2.4 2 1 0 2 2 1 1 SDA1 SpoIIP PF07454.11 CDJ66492.1 - 0.0002 20.9 39.2 0.013 14.9 13.2 2.3 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) PAT1 PF09770.9 CDJ66492.1 - 0.00027 19.4 70.6 0.0006 18.2 23.4 2.2 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 DUF5308 PF17233.2 CDJ66492.1 - 0.00063 20.0 5.0 0.00063 20.0 5.0 2.9 2 1 0 2 2 1 1 Family of unknown function (DUF5308) CDC45 PF02724.14 CDJ66492.1 - 0.0013 17.1 3.9 0.0013 17.1 3.9 2.2 2 0 0 2 2 2 1 CDC45-like protein LTV PF04180.14 CDJ66492.1 - 0.0027 17.5 29.5 0.0046 16.7 6.3 2.3 2 0 0 2 2 2 1 Low temperature viability protein TFIIA PF03153.13 CDJ66492.1 - 0.0064 16.5 46.0 0.0064 16.5 46.0 2.8 2 1 0 2 2 1 1 Transcription factor IIA, alpha/beta subunit PTPRCAP PF15713.5 CDJ66492.1 - 0.015 15.6 39.0 0.093 13.0 13.1 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CCSAP PF15748.5 CDJ66492.1 - 0.019 15.1 31.3 0.019 15.1 31.3 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated EOS1 PF12326.8 CDJ66492.1 - 0.033 14.1 20.4 0.37 10.7 5.7 2.6 2 0 0 2 2 2 0 N-glycosylation protein Raftlin PF15250.6 CDJ66492.1 - 0.04 12.7 32.7 0.1 11.3 8.3 2.1 2 0 0 2 2 2 0 Raftlin DUF572 PF04502.13 CDJ66492.1 - 0.045 13.4 40.2 0.064 12.9 15.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Peptidase_S64 PF08192.11 CDJ66492.1 - 0.067 11.7 31.9 0.29 9.6 9.3 2.3 2 0 0 2 2 2 0 Peptidase family S64 DUF2370 PF10176.9 CDJ66492.1 - 0.087 12.5 20.9 0.13 11.9 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) CPSF100_C PF13299.6 CDJ66492.1 - 0.089 13.0 33.9 1.2 9.3 13.0 2.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF2151 PF10221.9 CDJ66492.1 - 0.16 10.5 15.7 0.13 10.9 1.5 2.1 2 0 0 2 2 2 0 Cell cycle and development regulator DUF4471 PF14740.6 CDJ66492.1 - 0.17 11.1 22.2 0.072 12.3 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) CSRNP_N PF16019.5 CDJ66492.1 - 0.27 11.1 31.6 0.71 9.7 10.0 3.0 3 0 0 3 3 3 0 Cysteine/serine-rich nuclear protein N-terminus TCP PF03634.13 CDJ66492.1 - 0.28 11.7 59.8 0.46 11.0 32.0 2.7 2 1 0 2 2 2 0 TCP family transcription factor Endostatin PF06482.11 CDJ66492.1 - 0.32 10.4 42.9 1.5 8.2 19.0 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin DUF4045 PF13254.6 CDJ66492.1 - 0.34 10.5 47.6 0.25 10.9 20.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) UPF0565 PF10561.9 CDJ66492.1 - 0.43 9.8 16.7 0.15 11.2 1.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Connexin PF00029.19 CDJ66492.1 - 0.47 10.2 35.5 0.44 10.3 10.9 2.4 2 0 0 2 2 2 0 Connexin Ndc1_Nup PF09531.10 CDJ66492.1 - 0.6 8.7 43.3 0.19 10.4 11.5 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 CDJ66492.1 - 0.62 9.2 39.4 0.85 8.7 9.0 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein GramPos_pilinD1 PF16555.5 CDJ66492.1 - 0.64 10.2 20.3 1.1 9.4 4.0 2.5 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain Anoctamin PF04547.12 CDJ66492.1 - 0.67 8.7 17.9 0.013 14.3 4.4 2.2 2 0 0 2 2 2 0 Calcium-activated chloride channel ASC PF00858.24 CDJ66492.1 - 0.86 8.5 18.4 0.12 11.3 1.3 2.3 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel Hamartin PF04388.12 CDJ66492.1 - 0.9 8.1 42.7 0.74 8.4 19.8 2.1 2 0 0 2 2 2 0 Hamartin protein LAP1C PF05609.12 CDJ66492.1 - 0.98 8.4 49.6 0.85 8.6 24.3 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) RR_TM4-6 PF06459.12 CDJ66492.1 - 0.98 9.2 50.1 1.2 8.9 18.1 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PA26 PF04636.13 CDJ66492.1 - 1.4 7.7 31.4 1.4 7.8 12.3 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) DUF5523 PF17661.1 CDJ66492.1 - 1.8 8.2 44.9 2.3 7.8 16.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5523) TERB2 PF15101.6 CDJ66492.1 - 2.6 8.1 56.8 0.088 12.9 17.4 3.0 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF3292 PF11696.8 CDJ66492.1 - 2.7 6.3 37.3 0.68 8.2 9.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) CENP-N PF05238.13 CDJ66492.1 - 3.4 6.9 36.1 0.26 10.6 16.0 2.2 2 0 0 2 2 2 0 Kinetochore protein CHL4 like BSMAP PF12280.8 CDJ66492.1 - 3.5 7.8 33.5 4.8 7.3 12.0 2.8 2 0 0 2 2 2 0 Brain specific membrane anchored protein Velvet PF11754.8 CDJ66492.1 - 3.6 7.4 56.1 0.063 13.2 11.5 3.1 2 1 0 2 2 1 0 Velvet factor PPP4R2 PF09184.11 CDJ66492.1 - 3.9 7.0 32.9 0.39 10.3 12.7 2.2 2 0 0 2 2 2 0 PPP4R2 SID-1_RNA_chan PF13965.6 CDJ66492.1 - 4.1 5.7 21.8 0.49 8.7 4.4 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 ALMT PF11744.8 CDJ66492.1 - 4.8 5.9 34.7 3.3 6.4 14.3 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter RIFIN PF02009.16 CDJ66492.1 - 4.8 7.0 26.0 4.9 7.0 8.1 2.2 2 0 0 2 2 2 0 Rifin RAP1 PF07218.11 CDJ66492.1 - 5.7 5.1 4.8 8.4 4.5 2.9 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) BAF1_ABF1 PF04684.13 CDJ66492.1 - 5.9 5.8 37.0 4.3 6.3 14.0 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.22 CDJ66492.1 - 6 6.0 25.9 0.6 9.3 7.8 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Pal1 PF08316.11 CDJ66492.1 - 6.1 7.6 26.6 1.9 9.2 7.3 2.5 2 0 0 2 2 2 0 Pal1 cell morphology protein NPR3 PF03666.13 CDJ66492.1 - 6.1 5.5 45.5 0.19 10.5 13.2 2.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3807 PF12720.7 CDJ66492.1 - 6.6 7.0 61.7 1.1 9.5 23.7 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF3807) DUF5427 PF10310.9 CDJ66492.1 - 8.7 5.2 57.0 2 7.3 25.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5427) eIF-3_zeta PF05091.12 CDJ66492.1 - 8.8 5.2 64.4 4.5 6.1 27.8 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TT_ORF1 PF02956.14 CDJ66492.1 - 9.2 4.8 31.8 0.76 8.4 8.7 2.2 2 0 0 2 2 2 0 TT viral orf 1 Band_3_cyto PF07565.13 CDJ66492.1 - 9.2 6.0 43.9 6.8 6.4 17.5 2.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PP2C PF00481.21 CDJ66493.1 - 1.2e-06 28.4 0.0 1.3e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PepSY PF03413.19 CDJ66493.1 - 0.0067 17.0 0.0 0.0099 16.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain SpoIIE PF07228.12 CDJ66493.1 - 0.16 11.8 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) SR-25 PF10500.9 CDJ66494.1 - 0.0087 15.7 6.0 0.0087 15.7 6.0 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Androgen_recep PF02166.16 CDJ66494.1 - 0.0088 14.9 6.7 0.0088 14.9 6.7 3.2 3 0 0 3 3 3 1 Androgen receptor Na_H_antiport_3 PF07399.11 CDJ66494.1 - 0.018 13.9 0.3 0.066 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative Na+/H+ antiporter IMUP PF15761.5 CDJ66494.1 - 0.23 12.2 2.5 0.5 11.1 2.5 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF4050 PF13259.6 CDJ66494.1 - 0.61 10.4 8.0 0.11 12.8 0.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4050) RskA PF10099.9 CDJ66494.1 - 0.79 10.0 22.3 3.5 7.9 1.5 2.8 1 1 2 3 3 3 0 Anti-sigma-K factor rskA SARAF PF06682.12 CDJ66494.1 - 1.3 8.6 10.1 8.1 6.0 10.1 2.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Velvet PF11754.8 CDJ66494.1 - 2.3 8.1 12.0 0.036 14.0 2.3 2.0 1 1 0 2 2 2 0 Velvet factor KASH PF10541.9 CDJ66494.1 - 3.7 7.9 10.1 2.5 8.4 3.0 3.0 2 0 0 2 2 2 0 Nuclear envelope localisation domain Lactamase_B_6 PF16661.5 CDJ66496.1 - 4e-10 39.5 0.0 6e-06 25.8 0.0 2.7 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ66496.1 - 9.1e-07 29.1 0.1 3.1e-05 24.1 0.0 2.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ66496.1 - 0.00058 19.4 0.0 0.058 12.9 0.0 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF2722 PF10846.8 CDJ66496.1 - 0.0019 17.2 0.7 0.0024 16.9 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) APC1_C PF18122.1 CDJ66496.1 - 6.5 6.7 8.5 6.9 6.6 0.3 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain TFIIA PF03153.13 CDJ66496.1 - 8.9 6.2 12.2 14 5.6 12.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATG16 PF08614.11 CDJ66498.1 - 0.056 13.7 0.5 0.056 13.7 0.5 5.2 4 1 1 5 5 5 0 Autophagy protein 16 (ATG16) SR-25 PF10500.9 CDJ66498.1 - 0.59 9.7 22.9 0.025 14.2 6.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Metallophos PF00149.28 CDJ66499.1 - 3.6e-08 34.2 0.0 4.2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DNA_pol_E_B PF04042.16 CDJ66499.1 - 0.054 12.8 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B RIFIN PF02009.16 CDJ66500.1 - 0.019 14.9 11.2 0.081 12.8 2.6 2.2 2 0 0 2 2 2 0 Rifin PFK PF00365.20 CDJ66502.1 - 3.2e-52 177.6 0.1 6.5e-32 111.0 0.0 3.3 3 1 0 3 3 3 3 Phosphofructokinase Hydrolase_3 PF08282.12 CDJ66503.1 - 3.6e-43 148.1 0.0 4.4e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ66503.1 - 1.1e-07 31.6 0.1 0.00025 20.7 0.1 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CDJ66503.1 - 0.00059 20.2 0.6 0.013 15.8 0.2 2.5 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ66503.1 - 0.023 14.8 1.1 0.05 13.7 0.1 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ66503.1 - 0.067 13.6 1.2 0.14 12.5 0.0 2.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acyl_transf_1 PF00698.21 CDJ66506.1 - 3.2e-08 33.5 6.3 6.4e-05 22.6 2.5 2.1 1 1 1 2 2 2 2 Acyl transferase domain SR-25 PF10500.9 CDJ66506.1 - 0.021 14.4 19.0 0.036 13.7 19.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4667 PF15700.5 CDJ66506.1 - 0.035 14.2 6.1 0.051 13.7 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Cloacin PF03515.14 CDJ66506.1 - 0.066 12.9 4.3 0.087 12.5 4.3 1.2 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain Macoilin PF09726.9 CDJ66506.1 - 0.099 11.2 2.3 0.095 11.2 2.3 1.1 1 0 0 1 1 1 0 Macoilin family EBP50_C PF09007.11 CDJ66506.1 - 0.54 11.2 5.3 0.4 11.7 3.7 1.5 2 0 0 2 2 2 0 EBP50, C-terminal TFIIA PF03153.13 CDJ66506.1 - 0.61 10.0 6.7 0.73 9.8 6.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TAF4 PF05236.14 CDJ66506.1 - 0.91 9.2 4.3 1.5 8.5 4.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Period_C PF12114.8 CDJ66506.1 - 3.1 7.3 15.5 4.5 6.8 15.5 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region PAP1 PF08601.10 CDJ66506.1 - 3.8 7.1 11.6 3.8 7.1 10.7 1.5 2 0 0 2 2 2 0 Transcription factor PAP1 CCDC24 PF15669.5 CDJ66506.1 - 4.4 7.1 7.5 1 9.2 4.3 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family SRC-1 PF08832.10 CDJ66506.1 - 5.4 8.1 10.4 70 4.6 0.0 2.6 2 0 0 2 2 2 0 Steroid receptor coactivator Pex14_N PF04695.13 CDJ66507.1 - 0.0026 18.4 16.8 0.0033 18.1 16.8 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CDJ66507.1 - 0.004 16.0 11.7 0.0048 15.7 11.7 1.0 1 0 0 1 1 1 1 Presenilin Plasmodium_Vir PF05795.11 CDJ66507.1 - 0.024 14.1 2.9 0.029 13.8 2.9 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TFIIA PF03153.13 CDJ66507.1 - 0.043 13.8 22.9 0.046 13.7 22.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SMYLE_N PF18615.1 CDJ66507.1 - 0.053 13.1 9.6 0.057 13.0 9.6 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain BAF1_ABF1 PF04684.13 CDJ66507.1 - 0.065 12.3 11.3 0.073 12.1 11.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1635 PF07795.11 CDJ66507.1 - 0.089 12.6 8.0 0.11 12.4 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Lin-8 PF03353.15 CDJ66507.1 - 0.11 12.0 8.5 0.12 11.9 8.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MTBP_C PF14920.6 CDJ66507.1 - 0.13 11.9 12.8 0.14 11.9 12.8 1.1 1 0 0 1 1 1 0 MDM2-binding Miga PF10265.9 CDJ66507.1 - 0.14 11.1 7.7 0.16 10.9 7.7 1.0 1 0 0 1 1 1 0 Mitoguardin CCDC106 PF15794.5 CDJ66507.1 - 0.17 11.6 13.3 0.21 11.3 13.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Abhydrolase_9_N PF15420.6 CDJ66507.1 - 0.27 11.2 6.1 0.51 10.3 5.6 1.7 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus NPR3 PF03666.13 CDJ66507.1 - 0.27 10.0 8.7 0.3 9.8 8.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Velvet PF11754.8 CDJ66507.1 - 0.29 11.1 11.8 0.33 10.9 11.8 1.1 1 0 0 1 1 1 0 Velvet factor Raftlin PF15250.6 CDJ66507.1 - 0.35 9.6 8.3 0.38 9.4 8.3 1.0 1 0 0 1 1 1 0 Raftlin RR_TM4-6 PF06459.12 CDJ66507.1 - 0.37 10.6 11.0 0.42 10.4 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ66507.1 - 0.37 9.7 7.3 0.43 9.5 7.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 CDJ66507.1 - 0.43 9.5 9.3 0.48 9.4 9.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hamartin PF04388.12 CDJ66507.1 - 0.51 9.0 9.0 0.51 8.9 9.0 1.0 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 CDJ66507.1 - 0.55 8.8 12.9 0.6 8.7 12.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.13 CDJ66507.1 - 0.59 9.9 8.0 0.71 9.6 8.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Macoilin PF09726.9 CDJ66507.1 - 0.6 8.6 9.0 0.64 8.5 9.0 1.1 1 0 0 1 1 1 0 Macoilin family PA26 PF04636.13 CDJ66507.1 - 0.63 8.9 6.7 0.7 8.7 6.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Suf PF05843.14 CDJ66507.1 - 0.66 9.9 13.0 0.96 9.4 13.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM60A PF15396.6 CDJ66507.1 - 0.74 9.8 7.1 0.88 9.5 7.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Zip PF02535.22 CDJ66507.1 - 0.76 8.9 4.0 0.96 8.6 4.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter IHABP4_N PF16174.5 CDJ66507.1 - 0.76 10.4 18.1 1.1 9.8 18.1 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Menin PF05053.13 CDJ66507.1 - 0.86 7.9 9.9 0.97 7.7 9.9 1.1 1 0 0 1 1 1 0 Menin Tox-WTIP PF15654.6 CDJ66507.1 - 1.2 9.6 0.0 1.2 9.6 0.0 2.8 1 1 1 2 2 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif ASD2 PF08687.11 CDJ66507.1 - 1.5 8.3 13.9 1.7 8.1 13.9 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 RAP1 PF07218.11 CDJ66507.1 - 1.6 6.9 10.5 1.8 6.7 10.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Tmemb_cc2 PF10267.9 CDJ66507.1 - 1.7 7.7 14.8 1.9 7.5 14.8 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SAPS PF04499.15 CDJ66507.1 - 1.8 7.3 7.5 2 7.1 7.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BAT2_N PF07001.11 CDJ66507.1 - 1.9 8.9 23.1 2.6 8.4 23.1 1.2 1 0 0 1 1 1 0 BAT2 N-terminus Apt1 PF10351.9 CDJ66507.1 - 2.1 7.1 11.8 2.4 6.9 11.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SWI-SNF_Ssr4 PF08549.10 CDJ66507.1 - 2.3 6.7 17.4 2.7 6.5 17.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PAT1 PF09770.9 CDJ66507.1 - 2.4 6.3 17.2 2.7 6.1 17.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec62 PF03839.16 CDJ66507.1 - 2.4 7.6 6.0 2.9 7.3 6.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF5521 PF17659.1 CDJ66507.1 - 2.5 5.8 11.7 2.9 5.6 11.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Peptidase_S64 PF08192.11 CDJ66507.1 - 2.6 6.4 9.0 2.6 6.4 9.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF2464 PF10240.9 CDJ66507.1 - 2.9 7.4 8.5 3.5 7.1 8.5 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 GREB1 PF15782.5 CDJ66507.1 - 3.1 4.8 12.8 3.2 4.7 12.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4366 PF14283.6 CDJ66507.1 - 3.2 7.8 9.8 11 6.0 9.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) PNISR PF15996.5 CDJ66507.1 - 4.1 7.6 17.6 5.4 7.2 17.6 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Senescence_reg PF04520.13 CDJ66507.1 - 4.8 8.0 14.3 7.5 7.4 14.3 1.3 1 0 0 1 1 1 0 Senescence regulator Cyto_heme_lyase PF01265.17 CDJ66507.1 - 6.2 6.3 13.3 7.4 6.1 13.3 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase CAML PF14963.6 CDJ66507.1 - 6.3 6.8 8.2 7.7 6.6 8.2 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Sin_N PF04801.13 CDJ66507.1 - 7.9 5.6 19.0 10 5.2 19.0 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region RT_RNaseH_2 PF17919.1 CDJ66508.1 - 1.9e-24 85.6 0.0 3.9e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ66508.1 - 1.6e-16 60.5 0.0 4.8e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ66508.1 - 3.6e-14 52.6 3.0 3.8e-14 52.5 0.9 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CDJ66508.1 - 8.1e-13 48.6 0.0 4.7e-12 46.2 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ66508.1 - 0.00018 21.7 0.4 0.00039 20.6 0.4 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDJ66508.1 - 0.057 13.2 0.3 0.72 9.7 0.2 2.5 2 0 0 2 2 2 0 Integrase core domain Claudin_2 PF13903.6 CDJ66508.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Mvb12 PF09452.10 CDJ66508.1 - 0.076 13.5 0.1 0.28 11.6 0.0 2.0 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 THRAP3_BCLAF1 PF15440.6 CDJ66509.1 - 0.015 14.3 6.1 0.015 14.4 6.1 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Apt1 PF10351.9 CDJ66509.1 - 3 6.6 6.6 2.9 6.6 6.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mitofilin PF09731.9 CDJ66509.1 - 4 6.2 35.3 4.8 5.9 35.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein V_ATPase_I PF01496.19 CDJ66511.1 - 0.052 11.5 7.4 0.077 10.9 7.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CPSF100_C PF13299.6 CDJ66511.1 - 0.056 13.6 1.8 0.24 11.6 0.7 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PsbQ PF05757.11 CDJ66511.1 - 0.15 11.8 5.3 0.031 14.0 1.3 1.9 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) FAM176 PF14851.6 CDJ66511.1 - 0.28 10.8 2.6 1.1 8.9 1.2 2.0 2 0 0 2 2 2 0 FAM176 family DUF1524 PF07510.11 CDJ66511.1 - 0.41 10.5 5.7 0.72 9.7 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) EPL1 PF10513.9 CDJ66511.1 - 0.55 10.6 8.8 18 5.7 8.2 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Ribosomal_60s PF00428.19 CDJ66511.1 - 1.5 9.5 15.0 4.6 7.9 15.0 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1980 PF09323.10 CDJ66511.1 - 2.2 8.1 5.3 1.3 8.9 2.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Gti1_Pac2 PF09729.9 CDJ66511.1 - 5.4 7.1 8.8 5.5 7.0 3.7 2.0 2 0 0 2 2 2 0 Gti1/Pac2 family DUF4834 PF16118.5 CDJ66513.1 - 2.1e-05 25.4 0.4 3.6e-05 24.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ66513.1 - 0.00053 19.1 3.0 0.00061 18.9 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Peptidase_S49_N PF08496.10 CDJ66513.1 - 0.0021 18.1 0.7 0.0034 17.5 0.7 1.3 1 0 0 1 1 1 1 Peptidase family S49 N-terminal YfhO PF09586.10 CDJ66513.1 - 0.0025 16.2 5.0 0.0034 15.7 5.0 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO CBP_BcsG PF11658.8 CDJ66513.1 - 0.0095 14.4 0.9 0.014 13.8 0.9 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG CitMHS PF03600.16 CDJ66513.1 - 0.015 14.5 0.1 0.02 14.1 0.1 1.3 1 1 0 1 1 1 0 Citrate transporter DUF5313 PF17240.2 CDJ66513.1 - 0.034 14.6 2.1 0.083 13.3 2.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Pex24p PF06398.11 CDJ66513.1 - 0.037 13.0 0.1 0.052 12.5 0.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin RskA PF10099.9 CDJ66513.1 - 0.051 13.9 0.0 0.051 13.9 0.0 2.9 1 1 0 2 2 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ66513.1 - 0.059 13.4 10.3 0.072 13.1 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4446 PF14584.6 CDJ66513.1 - 0.14 12.2 0.3 0.27 11.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) V_ATPase_I PF01496.19 CDJ66513.1 - 0.19 9.6 1.7 0.28 9.1 1.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gastrin PF00918.17 CDJ66513.1 - 0.35 11.8 3.8 0.57 11.1 3.8 1.4 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Roughex PF06020.11 CDJ66513.1 - 0.36 9.9 3.5 0.46 9.5 3.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Med15 PF09606.10 CDJ66513.1 - 0.41 9.3 13.6 0.53 8.9 13.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2070 PF09843.9 CDJ66513.1 - 0.56 8.4 1.4 0.93 7.7 1.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5349 PF17298.2 CDJ66513.1 - 0.65 9.7 4.9 0.83 9.4 4.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF2572 PF10833.8 CDJ66513.1 - 0.99 9.1 9.1 1.8 8.2 9.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Ctr PF04145.15 CDJ66513.1 - 1.2 9.7 3.5 2.8 8.5 3.3 1.4 1 1 0 1 1 1 0 Ctr copper transporter family DUF3464 PF11947.8 CDJ66513.1 - 1.8 8.3 3.7 3.2 7.5 3.7 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Spt20 PF12090.8 CDJ66513.1 - 3.5 7.2 19.9 5 6.7 19.9 1.1 1 0 0 1 1 1 0 Spt20 family Utp14 PF04615.13 CDJ66516.1 - 0.02 13.5 0.0 0.02 13.5 0.0 4.8 3 1 2 5 5 5 0 Utp14 protein ESM4 PF15952.5 CDJ66517.1 - 0.0015 19.0 0.8 0.0015 19.0 0.8 3.2 3 1 0 3 3 3 1 Enhancer of split M4 family HTH_20 PF12840.7 CDJ66517.1 - 0.073 13.2 3.2 0.22 11.6 3.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Chorion_2 PF03964.15 CDJ66517.1 - 0.31 11.9 33.5 0.11 13.3 2.2 4.4 1 1 4 5 5 5 0 Chorion family 2 Spt20 PF12090.8 CDJ66517.1 - 0.75 9.4 37.5 0.11 12.1 11.7 2.6 3 0 0 3 3 3 0 Spt20 family Spore_III_AF PF09581.10 CDJ66517.1 - 1.7 8.6 6.5 1.4 8.9 0.4 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) PE_PPE_C PF12484.8 CDJ66517.1 - 2.4 9.1 35.3 0.41 11.6 10.4 3.4 3 0 0 3 3 3 0 Polymorphic PE/PPE proteins C terminal EPL1 PF10513.9 CDJ66517.1 - 2.7 8.4 10.3 4.1 7.8 3.5 2.5 2 1 0 2 2 2 0 Enhancer of polycomb-like SR-25 PF10500.9 CDJ66518.1 - 7e-07 29.1 55.7 6e-06 26.0 5.1 5.0 5 0 0 5 5 5 4 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ66519.1 - 2.4e-06 27.3 5.1 2.4e-06 27.3 5.1 3.0 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 CDJ66519.1 - 0.048 13.2 12.2 0.04 13.5 4.3 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Cwf_Cwc_15 PF04889.12 CDJ66519.1 - 0.2 11.3 2.1 3.7 7.2 0.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MMU163 PF17119.5 CDJ66519.1 - 0.45 9.6 6.5 0.067 12.3 1.2 2.0 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Apt1 PF10351.9 CDJ66519.1 - 0.72 8.6 11.7 0.63 8.8 3.5 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4614 PF15391.6 CDJ66519.1 - 3 7.8 19.9 0.77 9.7 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Transposase_24 PF03004.14 CDJ66519.1 - 3.1 7.9 9.9 0.41 10.8 0.9 2.3 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) Miga PF10265.9 CDJ66519.1 - 3.9 6.4 15.6 0.14 11.1 5.9 2.1 2 0 0 2 2 2 0 Mitoguardin Sin_N PF04801.13 CDJ66520.1 - 0.0011 18.3 19.2 0.0011 18.3 19.2 5.7 3 1 2 5 5 5 1 Sin-like protein conserved region DUF3801 PF12687.7 CDJ66520.1 - 0.0013 18.9 5.5 0.0013 18.9 5.5 5.3 4 1 1 5 5 5 2 Protein of unknown function (DUF3801) DUF2722 PF10846.8 CDJ66521.1 - 0.63 8.9 30.0 0.021 13.8 7.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) FecR PF04773.13 CDJ66522.1 - 0.023 15.3 0.9 0.029 15.0 0.9 1.4 1 1 0 1 1 1 0 FecR protein Med26_C PF15693.5 CDJ66522.1 - 9.4 6.3 9.9 11 6.1 9.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal PNISR PF15996.5 CDJ66523.1 - 6.5e-07 29.8 30.8 1.5e-06 28.6 30.8 1.6 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR Caldesmon PF02029.15 CDJ66523.1 - 1.6e-06 27.2 27.4 2e-06 26.9 27.4 1.2 1 0 0 1 1 1 1 Caldesmon FAM60A PF15396.6 CDJ66523.1 - 0.00029 20.9 26.0 0.00046 20.3 26.0 1.3 1 0 0 1 1 1 1 Protein Family FAM60A Ndc1_Nup PF09531.10 CDJ66523.1 - 0.0034 16.1 20.0 0.0047 15.7 20.0 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup MFS_4 PF06779.14 CDJ66523.1 - 0.013 14.8 2.0 0.025 13.9 2.0 1.4 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Apt1 PF10351.9 CDJ66523.1 - 0.41 9.5 22.5 0.57 9.0 22.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain LptF_LptG PF03739.14 CDJ66523.1 - 0.67 8.7 2.0 1.3 7.8 2.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG PAT1 PF09770.9 CDJ66523.1 - 0.77 8.0 63.2 1.1 7.4 63.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LAP1C PF05609.12 CDJ66523.1 - 0.79 8.8 37.4 1.1 8.2 37.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Dapper PF15268.6 CDJ66523.1 - 1.7 7.4 45.0 2.3 6.9 45.0 1.1 1 0 0 1 1 1 0 Dapper CDC45 PF02724.14 CDJ66523.1 - 2.2 6.5 39.6 3.2 6.0 39.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Exonuc_VII_L PF02601.15 CDJ66523.1 - 3 7.3 38.5 4.2 6.8 38.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4045 PF13254.6 CDJ66523.1 - 8.4 5.9 36.1 13 5.3 36.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF5345 PF17280.2 CDJ66524.1 - 0.00065 19.6 12.6 0.021 14.8 3.2 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5345) ACPS PF01648.20 CDJ66524.1 - 0.061 13.4 0.8 8.2 6.6 0.1 2.4 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase superfamily Presenilin PF01080.17 CDJ66524.1 - 0.17 10.6 16.2 0.19 10.5 16.2 1.1 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 CDJ66524.1 - 0.33 10.8 11.5 0.33 10.8 11.5 1.1 1 0 0 1 1 1 0 SPX domain V_ATPase_I PF01496.19 CDJ66524.1 - 0.54 8.1 9.9 0.61 7.9 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_28 PF13521.6 CDJ66524.1 - 0.71 10.1 7.3 0.34 11.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain Ndc1_Nup PF09531.10 CDJ66524.1 - 1.6 7.4 14.6 1.7 7.2 14.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SLC12 PF03522.15 CDJ66524.1 - 3.3 6.6 15.8 3.7 6.5 15.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ66524.1 - 5 6.9 17.1 8.3 6.1 17.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RPN13_C PF16550.5 CDJ66525.1 - 7.5e-12 45.4 4.3 7.5e-12 45.4 4.3 2.3 2 0 0 2 2 2 1 UCH-binding domain Spt20 PF12090.8 CDJ66525.1 - 0.28 10.8 12.7 0.51 9.9 12.7 1.4 1 0 0 1 1 1 0 Spt20 family GREB1 PF15782.5 CDJ66525.1 - 6.6 3.7 6.3 8 3.4 6.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer gag-asp_proteas PF13975.6 CDJ66527.1 - 0.0023 18.5 0.0 0.0042 17.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ66527.1 - 0.0045 17.6 0.0 0.0087 16.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF3552 PF12072.8 CDJ66527.1 - 0.0046 16.4 0.8 0.007 15.8 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) RVP_2 PF08284.11 CDJ66527.1 - 0.008 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease GET2 PF08690.10 CDJ66528.1 - 0.19 11.4 5.6 0.23 11.1 5.6 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIA PF03153.13 CDJ66528.1 - 0.35 10.8 23.8 0.41 10.6 23.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ66528.1 - 0.66 9.0 8.3 0.82 8.6 8.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RskA PF10099.9 CDJ66528.1 - 0.74 10.1 27.9 1.3 9.3 27.9 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RR_TM4-6 PF06459.12 CDJ66528.1 - 2.7 7.8 7.5 3.3 7.4 7.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CcmD PF04995.14 CDJ66529.1 - 0.0057 16.7 0.4 0.01 15.9 0.4 1.4 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) Spt20 PF12090.8 CDJ66529.1 - 0.046 13.3 2.9 0.055 13.1 2.9 1.2 1 0 0 1 1 1 0 Spt20 family PsbI PF02532.14 CDJ66530.1 - 0.26 11.3 2.2 0.51 10.3 2.2 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) X PF00739.19 CDJ66531.1 - 0.16 12.1 2.6 0.22 11.6 2.6 1.3 1 1 0 1 1 1 0 Trans-activation protein X Ribosomal_60s PF00428.19 CDJ66531.1 - 0.74 10.4 16.5 0.54 10.9 14.7 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein RR_TM4-6 PF06459.12 CDJ66532.1 - 0.0087 15.9 10.6 0.0095 15.8 10.6 1.0 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 CSG2 PF16965.5 CDJ66532.1 - 0.018 14.0 4.3 0.021 13.8 4.3 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator CobT PF06213.12 CDJ66532.1 - 0.023 14.1 16.1 0.033 13.6 16.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF5427 PF10310.9 CDJ66532.1 - 0.027 13.4 13.7 0.031 13.3 13.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CCDC53 PF10152.9 CDJ66532.1 - 0.042 14.3 12.9 0.052 14.0 12.9 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex V_ATPase_I PF01496.19 CDJ66532.1 - 0.054 11.4 12.8 0.06 11.3 12.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ66532.1 - 0.056 12.2 16.1 0.062 12.1 16.1 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CDJ66532.1 - 0.1 11.4 11.4 0.11 11.2 11.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CLN3 PF02487.17 CDJ66532.1 - 0.1 11.6 7.2 0.12 11.4 7.2 1.0 1 0 0 1 1 1 0 CLN3 protein DUF913 PF06025.12 CDJ66532.1 - 0.11 11.5 5.8 0.13 11.3 5.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BORG_CEP PF14957.6 CDJ66532.1 - 0.15 13.2 6.8 0.18 12.9 6.8 1.2 1 0 0 1 1 1 0 Cdc42 effector Suf PF05843.14 CDJ66532.1 - 0.15 12.0 17.4 0.2 11.6 17.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.17 CDJ66532.1 - 0.16 12.1 9.4 0.21 11.7 9.4 1.3 1 0 0 1 1 1 0 DDHD domain Connexin PF00029.19 CDJ66532.1 - 0.17 11.6 7.3 0.22 11.2 7.3 1.2 1 0 0 1 1 1 0 Connexin TFIIA PF03153.13 CDJ66532.1 - 0.2 11.6 39.9 0.23 11.4 39.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pox_Ag35 PF03286.14 CDJ66532.1 - 0.24 11.2 7.1 0.29 10.9 7.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2126 PF09899.9 CDJ66532.1 - 0.28 9.2 8.8 0.3 9.1 8.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF1180 PF06679.12 CDJ66532.1 - 0.32 11.4 4.3 0.42 11.0 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PAT1 PF09770.9 CDJ66532.1 - 0.33 9.2 25.4 0.37 9.0 25.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.16 CDJ66532.1 - 0.54 10.1 11.0 0.64 9.8 11.0 1.0 1 0 0 1 1 1 0 AUX/IAA family SLC12 PF03522.15 CDJ66532.1 - 0.56 9.2 13.2 0.62 9.0 13.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ66532.1 - 0.6 10.1 10.9 0.68 9.9 10.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MAJIN PF15077.6 CDJ66532.1 - 0.64 9.8 9.1 0.73 9.6 9.1 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF2828 PF11443.8 CDJ66532.1 - 0.67 8.0 12.4 0.79 7.7 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Serinc PF03348.15 CDJ66532.1 - 0.81 8.5 6.0 0.87 8.4 6.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM60A PF15396.6 CDJ66532.1 - 0.9 9.5 11.3 1.1 9.2 11.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4446 PF14584.6 CDJ66532.1 - 0.94 9.4 5.7 2.2 8.2 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) YABBY PF04690.13 CDJ66532.1 - 0.97 10.0 10.1 1.3 9.6 10.1 1.1 1 0 0 1 1 1 0 YABBY protein MMU163 PF17119.5 CDJ66532.1 - 0.99 8.5 5.1 1.2 8.2 5.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Ctr PF04145.15 CDJ66532.1 - 1 10.0 7.0 1.4 9.5 7.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Hydin_ADK PF17213.3 CDJ66532.1 - 1.1 9.5 9.4 1.5 9.1 9.4 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain FliP PF00813.20 CDJ66532.1 - 1.1 9.1 2.1 1.2 9.0 2.1 1.1 1 0 0 1 1 1 0 FliP family O-antigen_lig PF13425.6 CDJ66532.1 - 1.3 7.7 2.9 1.4 7.6 2.9 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Folate_carrier PF01770.18 CDJ66532.1 - 1.4 7.6 3.6 1.6 7.4 3.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF853 PF05872.12 CDJ66532.1 - 2.2 6.8 10.4 2.8 6.4 10.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Peptidase_S64 PF08192.11 CDJ66532.1 - 2.3 6.6 11.5 2.4 6.5 11.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 ALMT PF11744.8 CDJ66532.1 - 2.6 6.8 9.6 2.8 6.7 9.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Gti1_Pac2 PF09729.9 CDJ66532.1 - 2.6 8.1 12.0 3.3 7.7 12.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family HemX PF04375.14 CDJ66532.1 - 2.6 7.2 32.6 3.2 7.0 32.6 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Tim54 PF11711.8 CDJ66532.1 - 3.4 6.4 12.8 4.1 6.1 12.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GREB1 PF15782.5 CDJ66532.1 - 3.4 4.6 13.9 3.7 4.5 13.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PIP5K PF01504.18 CDJ66532.1 - 3.5 6.8 10.6 4.7 6.4 10.6 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Zip PF02535.22 CDJ66532.1 - 3.5 6.7 8.6 4.1 6.5 8.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Spore_coat_CotO PF14153.6 CDJ66532.1 - 4.1 7.3 21.0 5.7 6.8 21.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF4746 PF15928.5 CDJ66532.1 - 4.2 6.7 9.0 5.4 6.4 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) eIF-3_zeta PF05091.12 CDJ66532.1 - 5.4 5.9 25.4 6.8 5.5 25.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4638 PF15472.6 CDJ66532.1 - 5.5 6.7 12.8 6.6 6.4 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) HCO3_cotransp PF00955.21 CDJ66532.1 - 5.6 5.7 4.8 6.2 5.5 4.8 1.0 1 0 0 1 1 1 0 HCO3- transporter family Sec62 PF03839.16 CDJ66532.1 - 5.7 6.4 11.4 7.2 6.1 11.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Kei1 PF08552.11 CDJ66532.1 - 5.9 6.7 10.6 7.7 6.3 10.6 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Sin_N PF04801.13 CDJ66532.1 - 6.5 5.9 23.9 7.6 5.6 23.9 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF4175 PF13779.6 CDJ66532.1 - 7.2 4.4 37.8 8.3 4.2 37.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4407 PF14362.6 CDJ66532.1 - 7.9 5.7 18.2 9.7 5.4 18.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MMR1 PF08505.10 CDJ66532.1 - 8.4 6.6 19.2 10 6.3 19.2 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SseC PF04888.12 CDJ66533.1 - 0.0041 16.8 7.0 0.0041 16.8 7.0 4.3 4 0 0 4 4 4 1 Secretion system effector C (SseC) like family TFIIA PF03153.13 CDJ66534.1 - 7.4e-05 22.9 33.0 8.3e-05 22.8 33.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.8 CDJ66534.1 - 8.8e-05 21.8 37.4 0.00012 21.3 37.4 1.1 1 0 0 1 1 1 1 SprA-related family PAT1 PF09770.9 CDJ66534.1 - 0.00043 18.7 21.7 0.00043 18.7 21.7 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Spore_coat_CotO PF14153.6 CDJ66534.1 - 0.00078 19.4 23.2 0.0011 18.9 23.2 1.4 1 0 0 1 1 1 1 Spore coat protein CotO RR_TM4-6 PF06459.12 CDJ66534.1 - 0.0025 17.7 17.4 0.0035 17.2 17.4 1.3 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Raftlin PF15250.6 CDJ66534.1 - 0.004 16.0 10.0 0.0042 15.9 10.0 1.1 1 0 0 1 1 1 1 Raftlin EPL1 PF10513.9 CDJ66534.1 - 0.013 15.9 16.9 0.018 15.4 16.9 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Presenilin PF01080.17 CDJ66534.1 - 0.014 14.1 21.7 0.019 13.7 21.7 1.1 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 CDJ66534.1 - 0.017 14.8 15.2 0.02 14.6 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Lin-8 PF03353.15 CDJ66534.1 - 0.029 13.9 18.9 0.036 13.6 18.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ALMT PF11744.8 CDJ66534.1 - 0.034 13.0 11.5 0.041 12.7 11.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CDC45 PF02724.14 CDJ66534.1 - 0.036 12.4 16.5 0.042 12.2 16.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 CDJ66534.1 - 0.045 13.9 24.7 0.071 13.2 24.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Hydin_ADK PF17213.3 CDJ66534.1 - 0.057 13.7 15.5 0.08 13.2 15.5 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DDRGK PF09756.9 CDJ66534.1 - 0.068 12.8 28.1 0.095 12.3 28.1 1.3 1 0 0 1 1 1 0 DDRGK domain Velvet PF11754.8 CDJ66534.1 - 0.075 13.0 15.3 0.11 12.5 15.3 1.2 1 0 0 1 1 1 0 Velvet factor PTPRCAP PF15713.5 CDJ66534.1 - 0.087 13.1 20.8 0.17 12.2 20.8 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated NPR3 PF03666.13 CDJ66534.1 - 0.099 11.4 15.9 0.13 11.0 15.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 CDJ66534.1 - 0.13 11.3 17.3 0.16 11.0 17.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4175 PF13779.6 CDJ66534.1 - 0.19 9.6 44.8 2.4 6.0 41.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) eIF-3_zeta PF05091.12 CDJ66534.1 - 0.21 10.5 21.2 0.27 10.2 21.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Gti1_Pac2 PF09729.9 CDJ66534.1 - 0.22 11.6 12.7 0.33 11.0 12.7 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family BORG_CEP PF14957.6 CDJ66534.1 - 0.23 12.6 9.8 0.42 11.8 9.8 1.5 1 0 0 1 1 1 0 Cdc42 effector DUF2828 PF11443.8 CDJ66534.1 - 0.25 9.4 15.5 0.33 9.0 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.16 CDJ66534.1 - 0.27 11.3 14.1 0.37 10.8 14.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S64 PF08192.11 CDJ66534.1 - 0.27 9.7 12.1 0.33 9.4 12.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 CCSAP PF15748.5 CDJ66534.1 - 0.29 11.3 24.2 0.4 10.8 24.2 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CobT PF06213.12 CDJ66534.1 - 0.31 10.4 32.1 0.45 9.9 32.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AUX_IAA PF02309.16 CDJ66534.1 - 0.37 10.6 9.7 0.48 10.2 9.7 1.3 1 0 0 1 1 1 0 AUX/IAA family DUF4050 PF13259.6 CDJ66534.1 - 0.39 11.0 14.6 0.64 10.3 14.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Ndc1_Nup PF09531.10 CDJ66534.1 - 0.42 9.3 14.5 0.46 9.1 14.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM60A PF15396.6 CDJ66534.1 - 0.47 10.4 14.9 0.69 9.9 14.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SAPS PF04499.15 CDJ66534.1 - 0.51 9.1 13.0 0.58 8.9 13.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PEHE PF15275.6 CDJ66534.1 - 0.51 11.0 15.6 0.96 10.1 15.6 1.4 1 0 0 1 1 1 0 PEHE domain MAJIN PF15077.6 CDJ66534.1 - 0.58 9.9 16.2 0.93 9.2 16.2 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein VIR_N PF15912.5 CDJ66534.1 - 1 8.9 16.8 1.5 8.3 16.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal SID-1_RNA_chan PF13965.6 CDJ66534.1 - 1.1 7.6 5.2 1.2 7.5 5.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MDM10 PF12519.8 CDJ66534.1 - 1.4 7.7 13.7 1.8 7.3 13.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 TCP PF03634.13 CDJ66534.1 - 1.5 9.4 20.6 2.3 8.7 20.6 1.3 1 0 0 1 1 1 0 TCP family transcription factor Membralin PF09746.9 CDJ66534.1 - 1.8 7.6 10.0 2.3 7.2 10.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein Rtf2 PF04641.12 CDJ66534.1 - 1.8 7.9 23.2 2.8 7.2 23.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Asp-B-Hydro_N PF05279.11 CDJ66534.1 - 1.9 8.5 19.9 2.8 7.9 19.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Otopetrin PF03189.13 CDJ66534.1 - 2.7 6.7 8.5 3.2 6.5 8.5 1.1 1 0 0 1 1 1 0 Otopetrin Endostatin PF06482.11 CDJ66534.1 - 3.4 7.1 16.9 4.8 6.6 16.9 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin YABBY PF04690.13 CDJ66534.1 - 3.6 8.1 12.7 6.6 7.3 12.7 1.5 1 0 0 1 1 1 0 YABBY protein LMBR1 PF04791.16 CDJ66534.1 - 3.7 6.4 5.2 3.8 6.3 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase_fungal PF17667.1 CDJ66534.1 - 3.8 6.2 9.9 4.8 5.9 9.9 1.1 1 0 0 1 1 1 0 Fungal protein kinase PA26 PF04636.13 CDJ66534.1 - 3.9 6.3 12.2 4.9 6.0 12.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Herpes_DNAp_acc PF04929.12 CDJ66534.1 - 4.1 6.3 12.3 6.1 5.7 12.3 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor GREB1 PF15782.5 CDJ66534.1 - 5.2 4.0 21.1 6.2 3.8 21.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer 5_nucleotid PF05761.14 CDJ66534.1 - 6.8 5.5 11.8 9.2 5.0 11.8 1.2 1 0 0 1 1 1 0 5' nucleotidase family Zip PF02535.22 CDJ66534.1 - 7.4 5.7 10.9 10 5.3 10.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter O-antigen_lig PF13425.6 CDJ66534.1 - 8.7 5.0 9.7 11 4.7 9.7 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Prenyltrans PF00432.21 CDJ66535.1 - 2.4e-40 135.9 25.6 7.8e-10 38.3 0.0 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CDJ66535.1 - 2.2e-08 33.6 0.0 0.00057 19.1 0.0 3.8 1 1 3 4 4 4 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 CDJ66535.1 - 0.0033 16.5 0.0 0.07 12.1 0.0 2.2 2 0 0 2 2 2 1 A-macroglobulin TED domain SPX PF03105.19 CDJ66535.1 - 0.046 13.6 0.8 0.058 13.3 0.8 1.1 1 0 0 1 1 1 0 SPX domain SQHop_cyclase_C PF13243.6 CDJ66535.1 - 0.06 12.4 0.0 2 7.4 0.0 2.2 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain Mito_fiss_reg PF05308.11 CDJ66535.1 - 0.37 10.9 5.0 0.55 10.3 5.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 CDJ66535.1 - 0.67 9.4 2.5 1 8.8 2.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Apt1 PF10351.9 CDJ66535.1 - 6.7 5.5 5.2 8.9 5.0 5.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MFS_1 PF07690.16 CDJ66536.1 - 5.7e-28 97.9 30.3 7.3e-23 81.1 14.6 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CDJ66536.1 - 0.019 13.9 9.5 0.065 12.1 9.5 1.8 1 1 0 1 1 1 0 MFS_1 like family CDC50 PF03381.15 CDJ66538.1 - 2.9e-60 204.2 0.0 4e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1673 PF07895.11 CDJ66538.1 - 0.19 11.4 0.5 9.9 5.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Mlo PF03094.15 CDJ66540.1 - 1.3e-06 27.1 3.3 1.3e-06 27.1 3.3 1.9 1 1 1 2 2 2 1 Mlo family Baculo_VP91_N PF08475.10 CDJ66540.1 - 0.02 14.6 0.9 0.02 14.6 0.9 1.4 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal UPF0182 PF03699.13 CDJ66540.1 - 0.88 7.6 5.3 1 7.4 5.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DFP PF04127.15 CDJ66541.1 - 3.3e-12 46.6 12.8 5.3e-09 36.2 0.0 4.4 3 1 1 4 4 4 3 DNA / pantothenate metabolism flavoprotein DUF4746 PF15928.5 CDJ66541.1 - 0.0042 16.5 1.8 0.0072 15.8 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) LCE6A PF15858.5 CDJ66541.1 - 0.055 14.2 0.5 0.055 14.2 0.5 3.5 2 1 2 4 4 4 0 Late cornified envelope protein 6A family Spt20 PF12090.8 CDJ66541.1 - 0.1 12.2 9.5 0.17 11.5 9.5 1.4 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 CDJ66541.1 - 4.2 5.9 6.2 8.7 4.9 6.2 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_1 PF00515.28 CDJ66542.1 - 2.4e-13 49.2 9.5 1.9e-06 27.5 0.8 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ66542.1 - 9.2e-12 44.1 12.5 0.00023 21.0 0.3 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ66542.1 - 1.8e-06 27.5 5.4 0.024 14.3 0.4 3.6 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 CDJ66542.1 - 8e-05 22.9 1.1 8e-05 22.9 1.1 4.0 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ66542.1 - 0.0014 18.7 12.8 0.14 12.4 0.4 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ66542.1 - 0.0018 18.5 2.2 0.0059 16.9 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat BUD22 PF09073.10 CDJ66542.1 - 0.004 16.6 40.1 0.004 16.5 15.2 2.2 2 0 0 2 2 2 2 BUD22 Dapper PF15268.6 CDJ66542.1 - 0.054 12.3 39.2 0.25 10.2 18.1 2.1 2 0 0 2 2 2 0 Dapper TPR_10 PF13374.6 CDJ66542.1 - 0.12 12.3 6.2 16 5.5 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat eIF-3_zeta PF05091.12 CDJ66542.1 - 0.29 10.1 40.1 0.55 9.2 14.7 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ66542.1 - 0.34 9.1 54.2 0.46 8.7 21.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4179 PF13786.6 CDJ66542.1 - 0.41 11.2 1.5 2.9 8.4 1.5 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Hamartin PF04388.12 CDJ66542.1 - 1.4 7.5 27.9 1.4 7.5 10.0 2.2 2 0 0 2 2 2 0 Hamartin protein Presenilin PF01080.17 CDJ66542.1 - 1.6 7.4 47.0 0.67 8.7 21.4 2.3 2 0 0 2 2 2 0 Presenilin Sin_N PF04801.13 CDJ66542.1 - 2.4 7.3 45.1 0.033 13.4 18.0 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region CKAP2_C PF15297.6 CDJ66542.1 - 3.1 6.8 36.5 0.16 11.1 14.9 2.3 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus FAM60A PF15396.6 CDJ66542.1 - 4.1 7.3 35.4 3.2 7.7 12.9 2.5 2 0 0 2 2 2 0 Protein Family FAM60A UPF0565 PF10561.9 CDJ66542.1 - 4.4 6.4 17.5 0.72 9.0 6.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Endostatin PF06482.11 CDJ66542.1 - 4.4 6.7 29.3 3.3 7.1 11.0 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin PTPA PF03095.15 CDJ66543.1 - 1.5e-97 326.7 0.0 1.8e-97 326.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MIP PF00230.20 CDJ66545.1 - 3.2e-14 53.2 31.6 1.5e-07 31.4 13.9 3.7 1 1 2 3 3 3 3 Major intrinsic protein AAA PF00004.29 CDJ66546.1 - 2.1e-43 147.9 0.0 3.6e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ66546.1 - 4.1e-11 42.5 0.6 8.3e-11 41.5 0.6 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CDJ66546.1 - 8.5e-07 29.2 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ66546.1 - 1.7e-06 28.3 0.1 0.0018 18.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ66546.1 - 6.4e-06 26.7 0.2 0.00027 21.4 0.2 2.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CDJ66546.1 - 7e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CDJ66546.1 - 1.4e-05 24.4 0.0 2.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CDJ66546.1 - 3.1e-05 24.0 0.2 0.00019 21.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CDJ66546.1 - 0.0007 19.4 0.0 0.0027 17.4 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 CDJ66546.1 - 0.00075 20.0 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDJ66546.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ66546.1 - 0.0018 18.5 0.0 0.0061 16.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 CDJ66546.1 - 0.0024 17.1 0.0 0.0048 16.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 CDJ66546.1 - 0.0038 17.5 0.0 0.0082 16.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 CDJ66546.1 - 0.0046 16.4 0.0 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDJ66546.1 - 0.0062 16.9 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.11 CDJ66546.1 - 0.011 15.5 0.1 0.049 13.5 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CDJ66546.1 - 0.013 15.2 0.9 0.031 14.0 0.3 2.0 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CDJ66546.1 - 0.015 14.8 0.4 0.15 11.6 0.1 2.2 1 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDJ66546.1 - 0.02 14.4 0.0 0.068 12.7 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CDJ66546.1 - 0.026 14.4 0.0 0.26 11.2 0.0 2.1 1 1 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 CDJ66546.1 - 0.026 14.2 0.2 0.12 12.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CDJ66546.1 - 0.027 13.9 0.2 0.077 12.4 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 CDJ66546.1 - 0.029 14.3 0.3 0.29 11.0 0.1 2.4 2 1 0 2 2 2 0 NTPase ATPase PF06745.13 CDJ66546.1 - 0.032 13.6 0.1 0.48 9.7 0.1 2.2 1 1 0 2 2 2 0 KaiC ATPase_2 PF01637.18 CDJ66546.1 - 0.05 13.5 0.2 1.1 9.2 0.0 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 CDJ66546.1 - 0.052 14.0 0.3 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CDJ66546.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 CDJ66546.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 CDJ66546.1 - 0.094 12.4 0.0 0.46 10.2 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF1128 PF06569.11 CDJ66546.1 - 0.12 12.3 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) NB-ARC PF00931.22 CDJ66546.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 CDJ66546.1 - 0.15 12.6 0.1 0.3 11.6 0.1 1.9 1 1 0 1 1 1 0 ABC transporter Hamartin PF04388.12 CDJ66547.1 - 0.13 10.9 10.7 0.15 10.7 10.7 1.0 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 CDJ66547.1 - 0.16 12.0 30.9 0.18 11.7 30.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 CDJ66547.1 - 0.17 11.2 13.6 0.2 11.0 13.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FAM60A PF15396.6 CDJ66547.1 - 0.21 11.6 4.1 0.24 11.4 4.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 CDJ66547.1 - 0.24 10.1 13.8 0.27 10.0 13.8 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ66547.1 - 0.29 9.8 12.4 0.28 9.8 12.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spc7_N PF15402.6 CDJ66547.1 - 0.47 8.7 13.3 0.53 8.5 13.3 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF966 PF06136.13 CDJ66547.1 - 0.49 10.1 11.0 0.57 9.8 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Suf PF05843.14 CDJ66547.1 - 0.55 10.2 19.3 0.7 9.8 19.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SLC12 PF03522.15 CDJ66547.1 - 0.62 9.0 8.3 0.73 8.8 8.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 cwf18 PF08315.12 CDJ66547.1 - 0.9 10.2 10.9 1.2 9.9 10.9 1.1 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Zip PF02535.22 CDJ66547.1 - 1.4 8.0 4.4 1.4 8.1 4.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Podoplanin PF05808.11 CDJ66547.1 - 2.5 8.2 9.2 5 7.2 9.1 1.5 1 1 0 1 1 1 0 Podoplanin NST1 PF13945.6 CDJ66547.1 - 2.9 8.0 14.1 4.2 7.4 14.1 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator SRP-alpha_N PF04086.13 CDJ66547.1 - 2.9 7.7 12.8 3.4 7.5 12.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MCM3AP_GANP PF16769.5 CDJ66547.1 - 3.4 5.8 13.9 4.1 5.5 13.9 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP CENP-U PF13097.6 CDJ66547.1 - 4.2 7.3 14.7 6 6.8 14.7 1.3 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Band_3_cyto PF07565.13 CDJ66547.1 - 4.6 7.0 12.0 6 6.6 12.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 CDJ66547.1 - 7.3 6.6 11.1 9.1 6.3 11.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 CDJ66547.1 - 8.2 4.2 10.7 10 3.9 10.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec62 PF03839.16 CDJ66547.1 - 9.3 5.7 7.1 13 5.2 7.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 ABC_tran PF00005.27 CDJ66548.1 - 2.9e-16 60.2 0.0 1.2e-15 58.3 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ66548.1 - 1.1e-07 31.9 0.4 0.0067 16.3 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ66548.1 - 1.9e-07 30.8 0.4 0.00093 18.7 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CDJ66548.1 - 0.00056 20.2 0.0 0.00094 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ66548.1 - 0.0015 18.3 0.1 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CDJ66548.1 - 0.0015 18.3 0.0 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ66548.1 - 0.0036 17.2 0.2 0.018 15.0 0.1 2.0 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CDJ66548.1 - 0.0047 17.3 0.0 0.007 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 CDJ66548.1 - 0.0075 16.8 0.0 0.0099 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CDJ66548.1 - 0.025 14.5 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 CDJ66548.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 CDJ66548.1 - 0.059 13.4 0.0 0.17 11.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CDJ66548.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDJ66548.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CDJ66548.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 CDJ66548.1 - 0.12 11.5 0.1 0.46 9.6 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 CDJ66548.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_13 PF13166.6 CDJ66548.1 - 0.17 10.5 0.1 0.28 9.8 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ66548.1 - 0.19 11.5 0.0 0.44 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain zf-3CxxC_2 PF17180.4 CDJ66549.1 - 8.9e-12 45.6 7.7 8.9e-12 45.6 7.7 4.6 4 1 0 4 4 4 1 Zinc-binding domain SUIM_assoc PF16619.5 CDJ66551.1 - 0.051 13.6 0.5 0.051 13.6 0.5 9.2 4 2 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 AP2 PF00847.20 CDJ66551.1 - 3.4 8.0 9.0 7 7.0 0.0 4.0 3 0 0 3 3 3 0 AP2 domain UBA PF00627.31 CDJ66553.1 - 5.6e-09 35.7 1.2 1.6e-08 34.2 1.2 1.9 1 0 0 1 1 1 1 UBA/TS-N domain PUB PF09409.10 CDJ66553.1 - 2.5e-07 30.6 0.0 1.8e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 PUB domain CUE PF02845.16 CDJ66553.1 - 0.025 14.3 1.3 0.081 12.7 0.2 2.4 2 0 0 2 2 2 0 CUE domain DUF2344 PF10105.9 CDJ66553.1 - 0.56 10.0 5.7 0.047 13.5 0.7 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Imm5 PF14423.6 CDJ66553.1 - 0.59 10.3 3.1 0.71 10.1 0.1 2.4 1 1 1 2 2 2 0 Immunity protein Imm5 PRP1_N PF06424.12 CDJ66554.1 - 0.00017 22.0 0.8 0.00025 21.5 0.8 1.3 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal RskA PF10099.9 CDJ66554.1 - 0.0027 18.0 10.8 0.0039 17.5 10.8 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA AAA_23 PF13476.6 CDJ66554.1 - 0.018 15.6 4.3 0.017 15.6 4.3 1.1 1 0 0 1 1 1 0 AAA domain DUF4179 PF13786.6 CDJ66554.1 - 0.092 13.2 0.5 0.16 12.4 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) OMP_b-brl PF13505.6 CDJ66554.1 - 0.25 11.4 1.4 0.26 11.4 1.4 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain DUF5320 PF17253.2 CDJ66554.1 - 0.28 12.3 5.9 0.38 11.9 5.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5320) YL1 PF05764.13 CDJ66554.1 - 0.74 9.9 12.0 0.93 9.6 12.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein TFIIA PF03153.13 CDJ66554.1 - 5.1 7.0 23.7 6.4 6.7 23.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ66554.1 - 5.3 7.7 13.8 7.3 7.2 13.8 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IHABP4_N PF16174.5 CDJ66554.1 - 8.6 6.9 13.0 11 6.5 13.0 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal SET PF00856.28 CDJ66555.1 - 6.7e-17 62.4 2.5 4e-15 56.6 0.0 3.3 3 1 0 3 3 3 1 SET domain IMUP PF15761.5 CDJ66555.1 - 0.048 14.4 3.1 0.095 13.4 3.1 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Hydin_ADK PF17213.3 CDJ66555.1 - 0.23 11.7 7.3 0.069 13.4 1.9 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Hep_59 PF07052.11 CDJ66555.1 - 1.2 9.9 6.5 0.36 11.6 0.5 2.2 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 SR-25 PF10500.9 CDJ66555.1 - 1.7 8.2 10.4 0.12 12.0 5.1 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BAMBI PF06211.12 CDJ66555.1 - 2.6 8.3 6.7 0.75 10.1 2.4 2.2 2 0 0 2 2 2 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain EBP50_C PF09007.11 CDJ66555.1 - 6.2 7.8 10.5 1.5 9.8 2.1 2.3 2 0 0 2 2 2 0 EBP50, C-terminal Actin PF00022.19 CDJ66556.1 - 1.3e-73 248.0 0.2 1e-72 245.0 0.2 2.0 1 1 0 1 1 1 1 Actin DUF2722 PF10846.8 CDJ66556.1 - 0.0009 18.3 1.7 0.001 18.1 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF5336 PF17270.2 CDJ66556.1 - 0.0026 17.4 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5336) Spt20 PF12090.8 CDJ66556.1 - 0.0047 16.6 8.3 0.0068 16.0 8.3 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ66556.1 - 0.0087 16.1 3.6 0.0098 15.9 3.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Homoserine_dh PF00742.19 CDJ66556.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase Androgen_recep PF02166.16 CDJ66556.1 - 2.5 6.8 15.6 3.8 6.2 15.6 1.2 1 0 0 1 1 1 0 Androgen receptor MutS_V PF00488.21 CDJ66557.1 - 1.6e-07 31.6 0.1 3.5e-07 30.4 0.1 1.7 1 1 0 1 1 1 1 MutS domain V TFIIA PF03153.13 CDJ66560.1 - 5.8 6.8 18.9 0.56 10.1 13.8 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glt_symporter PF03616.14 CDJ66561.1 - 0.2 10.3 0.9 1.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Sodium/glutamate symporter SID-1_RNA_chan PF13965.6 CDJ66561.1 - 4.7 5.5 7.3 0.88 7.9 0.5 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 eIF-3_zeta PF05091.12 CDJ66561.1 - 8.9 5.2 27.1 0.51 9.3 7.2 2.6 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DFRP_C PF16543.5 CDJ66563.1 - 8.6e-17 61.4 1.2 8.6e-17 61.4 1.2 3.6 3 1 1 4 4 4 2 DRG Family Regulatory Proteins, Tma46 RskA PF10099.9 CDJ66564.1 - 1.6 9.0 36.7 4 7.7 9.8 3.2 1 1 2 3 3 3 0 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ66564.1 - 5.1 7.6 9.2 2.9e+02 2.0 7.5 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) Coatomer_E PF04733.14 CDJ66565.1 - 1e-12 48.1 2.7 1.8e-12 47.3 2.7 1.4 1 0 0 1 1 1 1 Coatomer epsilon subunit Proteasom_PSMB PF10508.9 CDJ66565.1 - 0.025 13.1 0.1 0.04 12.4 0.1 1.5 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit TPR_19 PF14559.6 CDJ66565.1 - 0.028 14.9 0.1 0.028 14.9 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ66565.1 - 0.045 13.8 4.9 0.073 13.1 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CDJ66565.1 - 0.078 13.4 1.8 0.5 10.8 0.1 2.6 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_14 PF13428.6 CDJ66565.1 - 0.13 13.2 0.1 0.13 13.2 0.1 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat RskA PF10099.9 CDJ66566.1 - 0.54 10.5 0.0 0.45 10.8 3.7 38.5 17 9 8 29 29 29 0 Anti-sigma-K factor rskA FapA PF03961.13 CDJ66567.1 - 8.6 4.8 7.4 8 4.9 0.0 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A Peptidase_M56 PF05569.11 CDJ66572.1 - 0.085 12.0 0.3 0.15 11.2 0.1 1.5 1 1 0 1 1 1 0 BlaR1 peptidase M56 SR-25 PF10500.9 CDJ66572.1 - 0.51 9.9 38.0 1.6 8.3 15.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Mucin PF01456.17 CDJ66572.1 - 6.3 6.8 9.8 4.4 7.3 1.1 2.4 2 1 0 2 2 2 0 Mucin-like glycoprotein Presenilin PF01080.17 CDJ66573.1 - 0.13 11.0 5.4 0.13 11.0 5.4 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ66573.1 - 1.2 6.2 15.2 1.2 6.2 15.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 CDJ66573.1 - 1.9 7.6 27.5 2 7.5 27.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 CDJ66573.1 - 3 6.3 22.0 4.4 5.8 22.0 1.3 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ66573.1 - 4.6 6.0 25.0 5.4 5.8 25.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HemX PF04375.14 CDJ66574.1 - 0.0072 15.6 10.5 0.0072 15.6 10.5 1.5 2 0 0 2 2 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase RT_RNaseH PF17917.1 CDJ66574.1 - 0.17 12.2 1.4 0.35 11.2 1.4 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase BatA PF07584.11 CDJ66574.1 - 4.6 7.7 9.7 0.32 11.4 0.5 2.8 2 1 0 2 2 2 0 Aerotolerance regulator N-terminal Helicase_C PF00271.31 CDJ66575.1 - 3.1e-11 43.6 0.0 6.3e-10 39.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Sec63 PF02889.16 CDJ66575.1 - 1.9e-08 33.8 0.1 5.6e-08 32.3 0.1 1.7 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.29 CDJ66575.1 - 0.0013 18.6 0.0 0.0036 17.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ66575.1 - 0.008 16.2 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 CDJ66575.1 - 0.033 14.8 0.6 0.082 13.5 0.1 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain Cdd1 PF11731.8 CDJ66575.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus DUF2722 PF10846.8 CDJ66576.1 - 0.0095 14.9 0.9 0.011 14.8 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) IPK PF03770.16 CDJ66576.1 - 0.043 13.7 0.0 0.083 12.7 0.0 1.4 1 1 0 1 1 1 0 Inositol polyphosphate kinase eIF3_p135 PF12807.7 CDJ66576.1 - 0.049 13.7 0.4 0.073 13.1 0.4 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Med15 PF09606.10 CDJ66576.1 - 0.087 11.5 8.1 0.11 11.1 8.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3464 PF11947.8 CDJ66576.1 - 0.088 12.6 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2644 PF10841.8 CDJ66576.1 - 0.097 12.9 0.7 0.29 11.4 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) Spt20 PF12090.8 CDJ66576.1 - 6.5 6.3 14.3 9.5 5.7 14.3 1.1 1 0 0 1 1 1 0 Spt20 family FabA PF07977.13 CDJ66577.1 - 1.5e-27 95.9 0.0 1.8e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain Androgen_recep PF02166.16 CDJ66577.1 - 3.8 6.3 9.9 5.2 5.8 9.9 1.1 1 0 0 1 1 1 0 Androgen receptor Scs3p PF10261.9 CDJ66578.1 - 0.27 10.7 2.5 0.32 10.5 2.5 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Presenilin PF01080.17 CDJ66578.1 - 4.4 6.0 11.5 5 5.8 11.5 1.1 1 0 0 1 1 1 0 Presenilin Hydin_ADK PF17213.3 CDJ66578.1 - 4.4 7.5 9.1 7.1 6.9 9.1 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PAT1 PF09770.9 CDJ66578.1 - 4.9 5.3 25.7 5.4 5.2 25.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 CDJ66578.1 - 6.6 6.2 19.1 9.5 5.7 19.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Gti1_Pac2 PF09729.9 CDJ66578.1 - 7 6.7 9.1 9.6 6.3 9.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family ANAPC_CDC26 PF10471.9 CDJ66579.1 - 0.0043 17.8 14.7 0.0068 17.2 14.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 RAB3GAP2_N PF14655.6 CDJ66579.1 - 0.0046 16.3 0.5 0.0063 15.8 0.5 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIA PF03153.13 CDJ66579.1 - 0.045 13.7 18.5 0.061 13.3 18.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ephrin_rec_like PF07699.13 CDJ66579.1 - 0.047 13.5 0.2 0.047 13.5 0.2 8.0 7 1 1 8 8 8 0 Putative ephrin-receptor like Presenilin PF01080.17 CDJ66579.1 - 0.061 12.1 0.6 0.078 11.7 0.6 1.1 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ66579.1 - 0.56 9.1 23.1 0.78 8.6 23.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ66579.1 - 0.75 9.7 9.8 1 9.3 9.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 CDJ66579.1 - 0.77 10.4 10.5 1.2 9.8 10.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CobT PF06213.12 CDJ66579.1 - 0.83 9.0 9.3 1.2 8.5 9.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pex26 PF07163.12 CDJ66579.1 - 0.86 8.9 4.0 1.2 8.4 4.0 1.1 1 0 0 1 1 1 0 Pex26 protein DUF775 PF05603.12 CDJ66579.1 - 1.4 8.4 7.0 2 7.9 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4407 PF14362.6 CDJ66579.1 - 3.5 6.9 6.5 5.1 6.4 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 CDJ66579.1 - 5.6 5.8 10.4 7.7 5.4 10.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 CDJ66579.1 - 6.4 6.3 32.4 8.9 5.9 32.4 1.1 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ66579.1 - 9.1 7.3 11.1 16 6.6 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TERB2 PF15101.6 CDJ66579.1 - 9.2 6.3 10.8 13 5.8 10.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Coilin_N PF15862.5 CDJ66579.1 - 9.3 6.1 9.1 14 5.4 9.1 1.2 1 0 0 1 1 1 0 Coilin N-terminus EF-hand_1 PF00036.32 CDJ66580.1 - 2.3e-31 105.0 4.5 4.7e-08 32.0 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ66580.1 - 7.2e-26 90.4 0.1 1.4e-12 47.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ66580.1 - 1.4e-25 87.0 0.5 6.6e-07 28.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ66580.1 - 1.4e-23 81.3 5.2 1.1e-06 27.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDJ66580.1 - 5.6e-20 70.9 8.7 2.5e-09 36.8 0.3 4.4 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CDJ66580.1 - 1.1e-07 31.7 1.5 0.0019 18.1 0.0 2.9 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ66580.1 - 2e-06 28.1 0.0 0.0032 17.8 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDJ66580.1 - 2.7e-05 24.4 0.0 0.006 16.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain DUF2267 PF10025.9 CDJ66580.1 - 0.00095 19.4 0.0 0.018 15.3 0.0 2.2 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2267) TerB PF05099.13 CDJ66580.1 - 0.022 14.7 0.1 0.17 11.9 0.0 2.0 1 1 1 2 2 2 0 Tellurite resistance protein TerB Dockerin_1 PF00404.18 CDJ66580.1 - 0.041 14.1 0.5 5.8 7.2 0.0 3.2 4 0 0 4 4 4 0 Dockerin type I domain Toprim_2 PF13155.6 CDJ66580.1 - 0.12 12.8 0.1 0.48 10.9 0.0 2.0 1 1 2 3 3 3 0 Toprim-like Helicase_C PF00271.31 CDJ66582.1 - 1.2e-09 38.5 0.0 1.2e-09 38.5 0.0 3.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Cyclin_C PF02984.19 CDJ66583.1 - 0.0059 16.7 0.1 0.0059 16.7 0.1 3.2 2 1 0 2 2 2 1 Cyclin, C-terminal domain SUIM_assoc PF16619.5 CDJ66584.1 - 0.00086 19.3 7.6 0.00086 19.3 7.6 3.0 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ66584.1 - 0.0029 17.2 8.7 0.0029 17.2 8.7 1.6 2 0 0 2 2 2 1 Spt20 family DUF3446 PF11928.8 CDJ66584.1 - 0.22 11.8 39.7 1.2 9.4 13.6 3.0 3 0 0 3 3 3 0 Early growth response N-terminal domain TAF4 PF05236.14 CDJ66584.1 - 1.2 8.8 8.6 5.1 6.8 8.6 1.8 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4207 PF13904.6 CDJ66585.1 - 1.3e-05 25.0 22.4 0.0027 17.5 4.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4207) Dsh_C PF12316.8 CDJ66585.1 - 0.0087 16.5 13.7 0.0087 16.5 13.7 2.2 2 1 0 2 2 1 1 Segment polarity protein dishevelled (Dsh) C terminal Spt20 PF12090.8 CDJ66585.1 - 0.011 15.4 42.6 0.018 14.7 9.6 2.2 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 CDJ66585.1 - 0.017 15.2 9.0 0.017 15.2 9.0 3.7 3 1 0 3 3 1 0 Unstructured region C-term to UIM in Ataxin3 MAM33 PF02330.16 CDJ66585.1 - 0.019 14.9 4.3 0.24 11.3 1.7 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein PPI_Ypi1 PF07491.11 CDJ66585.1 - 0.029 14.2 2.3 0.029 14.2 2.3 4.0 3 1 1 4 4 3 0 Protein phosphatase inhibitor EPL1 PF10513.9 CDJ66585.1 - 0.053 13.9 14.7 0.9 9.9 1.7 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like SR-25 PF10500.9 CDJ66585.1 - 0.055 13.1 41.0 0.068 12.8 11.0 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein PH_4 PF15404.6 CDJ66585.1 - 0.18 11.5 7.6 0.24 11.2 1.8 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain V_ATPase_I PF01496.19 CDJ66585.1 - 0.2 9.6 9.8 0.037 12.0 3.4 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ66585.1 - 0.2 11.4 4.2 0.34 10.6 0.8 2.1 2 0 0 2 2 2 0 Connexin eIF-3_zeta PF05091.12 CDJ66585.1 - 0.41 9.6 15.0 0.14 11.2 5.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM176 PF14851.6 CDJ66585.1 - 0.45 10.2 6.6 0.29 10.8 1.6 2.3 2 0 0 2 2 2 0 FAM176 family DUF1980 PF09323.10 CDJ66585.1 - 0.49 10.3 8.9 3.1 7.7 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PRP3 PF08572.10 CDJ66585.1 - 0.52 10.0 15.1 2.4 7.8 6.5 2.2 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) TFB6 PF17110.5 CDJ66585.1 - 0.62 9.8 4.1 1.7 8.4 1.4 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Peptidase_S49_N PF08496.10 CDJ66585.1 - 0.75 9.9 9.3 5.6 7.0 4.5 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3408 PF11888.8 CDJ66585.1 - 0.75 9.9 12.1 1.9 8.6 6.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Apt1 PF10351.9 CDJ66585.1 - 0.82 8.5 13.9 0.49 9.2 3.1 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain RAB3GAP2_N PF14655.6 CDJ66585.1 - 0.84 8.8 15.9 0.52 9.5 4.1 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2681 PF10883.8 CDJ66585.1 - 0.9 10.0 28.2 0.13 12.7 11.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) PA26 PF04636.13 CDJ66585.1 - 1.2 8.0 11.2 1.7 7.5 2.1 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Hydin_ADK PF17213.3 CDJ66585.1 - 1.2 9.3 32.1 4.1 7.6 13.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Band_3_cyto PF07565.13 CDJ66585.1 - 1.9 8.2 13.8 3.1 7.5 5.3 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4820 PF16091.5 CDJ66585.1 - 2.1 7.7 15.7 0.6 9.4 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) INSIG PF07281.12 CDJ66585.1 - 2.3 7.8 7.9 1.6 8.3 1.5 2.3 2 1 0 2 2 2 0 Insulin-induced protein (INSIG) DUF4770 PF15994.5 CDJ66585.1 - 2.7 8.2 14.5 4.7 7.4 7.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) EIIBC-GUT_N PF03612.14 CDJ66585.1 - 3.2 7.4 12.6 3.2 7.4 5.3 2.5 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2407 PF10302.9 CDJ66585.1 - 3.2 8.3 7.6 4.8 7.8 3.3 2.3 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain SpoIIP PF07454.11 CDJ66585.1 - 3.4 7.0 12.8 4 6.8 7.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF3464 PF11947.8 CDJ66585.1 - 3.9 7.2 14.3 9.8 5.9 7.3 2.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 RR_TM4-6 PF06459.12 CDJ66585.1 - 4.4 7.0 13.4 1.9 8.3 5.4 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Eapp_C PF10238.9 CDJ66585.1 - 5.1 7.2 15.7 4.9 7.2 7.6 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein Thg1C PF14413.6 CDJ66585.1 - 5.5 7.2 10.5 20 5.3 4.9 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain DUF3381 PF11861.8 CDJ66585.1 - 5.6 6.7 15.2 9.4 6.0 7.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Hid1 PF12722.7 CDJ66585.1 - 5.8 4.9 15.9 2.8 6.0 5.1 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DivIC PF04977.15 CDJ66585.1 - 5.9 6.7 23.1 2.8 7.8 4.0 2.3 2 0 0 2 2 2 0 Septum formation initiator CLN3 PF02487.17 CDJ66585.1 - 6.2 5.7 8.9 15 4.5 4.1 2.2 2 0 0 2 2 2 0 CLN3 protein Bud13 PF09736.9 CDJ66585.1 - 9.3 6.6 18.9 5.1 7.5 7.5 2.5 3 0 0 3 3 2 0 Pre-mRNA-splicing factor of RES complex DUF1269 PF06897.12 CDJ66587.1 - 0.02 15.1 0.9 0.06 13.6 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) BPD_transp_2 PF02653.16 CDJ66587.1 - 0.41 9.8 9.1 0.62 9.2 9.1 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Ribosomal_60s PF00428.19 CDJ66587.1 - 1.9 9.1 9.2 16 6.2 5.6 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pkinase PF00069.25 CDJ66588.1 - 2.5e-27 95.9 0.0 1.8e-26 93.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ66588.1 - 1.5e-17 63.7 0.0 8.9e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDJ66588.1 - 0.024 14.6 9.2 0.082 12.8 9.2 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family BUD22 PF09073.10 CDJ66589.1 - 0.038 13.3 36.9 0.041 13.2 36.9 1.2 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 CDJ66589.1 - 0.17 11.8 31.5 0.22 11.4 31.5 1.4 1 0 0 1 1 1 0 SPX domain Nop14 PF04147.12 CDJ66589.1 - 2.3 6.3 26.6 2.9 6.0 26.6 1.3 1 0 0 1 1 1 0 Nop14-like family DUF572 PF04502.13 CDJ66589.1 - 9.5 5.7 21.9 10 5.6 21.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF5098 PF17023.5 CDJ66590.1 - 0.0002 20.5 2.1 0.00029 19.9 1.8 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF5098) Asp-B-Hydro_N PF05279.11 CDJ66590.1 - 0.0095 16.0 16.8 0.016 15.3 16.8 1.3 1 0 0 1 1 1 1 Aspartyl beta-hydroxylase N-terminal region DUF4936 PF16290.5 CDJ66590.1 - 0.17 12.6 4.5 0.23 12.2 2.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4936) MeaB PF03308.16 CDJ66590.1 - 1.5 7.8 5.3 2.7 6.9 5.1 1.6 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cytochrom_NNT PF03264.14 CDJ66590.1 - 1.5 8.5 8.6 1.3 8.7 6.5 2.0 1 1 1 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region FapA PF03961.13 CDJ66590.1 - 4.1 5.9 15.7 5.6 5.5 15.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A FUSC PF04632.12 CDJ66590.1 - 4.2 5.8 10.8 5.5 5.4 10.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ephrin_rec_like PF07699.13 CDJ66592.1 - 0.023 14.5 1.6 0.028 14.2 0.1 2.0 2 0 0 2 2 2 0 Putative ephrin-receptor like Notch PF00066.17 CDJ66592.1 - 0.13 12.8 3.9 0.16 12.5 0.9 2.2 2 0 0 2 2 2 0 LNR domain Lustrin_cystein PF14625.6 CDJ66593.1 - 0.21 12.0 77.9 1.1 9.7 1.9 10.2 4 3 4 8 8 8 0 Lustrin, cysteine-rich repeated domain Ephrin_rec_like PF07699.13 CDJ66594.1 - 1e-06 28.4 32.3 7.3e-05 22.5 9.3 4.4 2 2 1 4 4 4 3 Putative ephrin-receptor like NCD3G PF07562.14 CDJ66594.1 - 0.018 15.0 25.0 0.062 13.3 5.2 4.6 3 3 0 4 4 4 0 Nine Cysteines Domain of family 3 GPCR Lustrin_cystein PF14625.6 CDJ66594.1 - 0.036 14.4 39.6 0.17 12.3 4.9 6.2 3 2 3 6 6 6 0 Lustrin, cysteine-rich repeated domain Dickkopf_N PF04706.12 CDJ66594.1 - 0.34 11.4 25.2 21 5.7 2.6 5.3 3 2 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region NHL PF01436.21 CDJ66595.1 - 6.7e-13 48.0 0.4 0.022 14.8 0.0 4.0 4 0 0 4 4 4 3 NHL repeat SGL PF08450.12 CDJ66595.1 - 0.00013 21.6 0.5 0.078 12.5 0.1 3.2 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 CDJ66595.1 - 0.06 13.5 1.0 0.63 10.3 0.0 2.8 4 0 0 4 4 4 0 Arylesterase Dickkopf_N PF04706.12 CDJ66596.1 - 1.4 9.4 14.1 24 5.5 3.7 3.3 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Inhibitor_I36 PF03995.13 CDJ66596.1 - 9.2 6.3 9.3 2 8.4 0.5 3.1 3 0 0 3 3 3 0 Peptidase inhibitor family I36 NCD3G PF07562.14 CDJ66597.1 - 0.009 16.0 4.7 0.87 9.6 0.7 2.3 2 0 0 2 2 2 2 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.13 CDJ66597.1 - 0.013 15.2 9.3 0.018 14.8 5.2 2.3 1 1 1 2 2 2 0 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 CDJ66598.1 - 1e-06 28.4 35.5 2.1e-05 24.2 2.2 4.7 4 1 1 5 5 5 3 Putative ephrin-receptor like TNFR_c6 PF00020.18 CDJ66598.1 - 3.1 8.3 28.3 0.4 11.1 0.9 5.2 4 2 2 6 6 6 0 TNFR/NGFR cysteine-rich region Lustrin_cystein PF14625.6 CDJ66599.1 - 0.00013 22.3 18.6 0.02 15.2 2.6 3.9 4 0 0 4 4 4 3 Lustrin, cysteine-rich repeated domain FOLN PF09289.10 CDJ66599.1 - 0.14 12.4 5.8 15 5.9 0.3 3.9 4 0 0 4 4 4 0 Follistatin/Osteonectin-like EGF domain Granulin PF00396.18 CDJ66599.1 - 1.1 9.6 17.8 2.5 8.5 1.0 4.2 4 0 0 4 4 4 0 Granulin Opy2 PF09463.10 CDJ66599.1 - 4.9 7.6 19.4 1.6 9.1 0.9 4.1 4 1 0 4 4 4 0 Opy2 protein Ephrin_rec_like PF07699.13 CDJ66599.1 - 7 6.5 18.7 1.6 8.5 0.4 4.5 4 1 1 5 5 5 0 Putative ephrin-receptor like CBM_19 PF03427.13 CDJ66599.1 - 7.5 6.6 18.2 3.3 7.8 0.1 4.6 3 2 2 5 5 5 0 Carbohydrate binding domain (family 19) fn3_6 PF17766.1 CDJ66600.1 - 0.11 12.7 0.0 2.4 8.4 0.0 3.1 3 0 0 3 3 3 0 Fibronectin type-III domain Tctex-1 PF03645.13 CDJ66601.1 - 1.2e-19 70.4 0.0 1.4e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF641 PF04859.12 CDJ66602.1 - 0.05 14.0 4.3 0.2 12.0 4.3 2.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) CENP-K PF11802.8 CDJ66602.1 - 2.1 7.9 11.3 0.067 12.8 3.6 2.1 2 0 0 2 2 2 0 Centromere-associated protein K Baculo_F PF12259.8 CDJ66602.1 - 3 6.3 6.2 4.4 5.7 1.0 2.1 2 0 0 2 2 2 0 Baculovirus F protein DUF2408 PF10303.9 CDJ66602.1 - 5.4 7.6 8.5 2.4 8.7 4.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Dynein_C PF18199.1 CDJ66604.1 - 2.1e-18 66.6 0.0 2.4e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CDJ66605.1 - 6.5e-84 281.3 0.0 1.2e-81 273.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ66605.1 - 6.9e-74 247.7 0.2 6.9e-74 247.7 0.2 2.6 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDJ66605.1 - 5.2e-61 205.3 0.0 2.3e-60 203.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 CDJ66605.1 - 6.9e-24 84.4 0.0 1.9e-23 82.9 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ66605.1 - 2.5e-17 62.9 1.0 8e-17 61.3 0.2 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 CDJ66605.1 - 2.9e-15 56.5 0.0 1.9e-06 27.9 0.0 4.1 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) MT PF12777.7 CDJ66605.1 - 3.4e-08 32.9 8.4 7.2e-08 31.8 8.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA PF00004.29 CDJ66605.1 - 0.0012 19.3 0.0 0.012 16.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CppA_C PF14507.6 CDJ66605.1 - 0.065 14.0 0.0 0.46 11.3 0.0 2.4 2 0 0 2 2 2 0 CppA C-terminal AAA_14 PF13173.6 CDJ66605.1 - 0.07 13.2 0.0 0.32 11.1 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 CDJ66605.1 - 0.13 12.6 8.1 0.72 10.2 0.1 4.2 4 2 0 4 4 4 0 AAA ATPase domain VIT1 PF01988.19 CDJ66605.1 - 0.14 12.0 3.2 0.28 11.0 3.2 1.5 1 0 0 1 1 1 0 VIT family AAA_22 PF13401.6 CDJ66605.1 - 0.2 11.9 2.7 0.38 11.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain Atg14 PF10186.9 CDJ66605.1 - 0.89 8.6 7.1 2.1 7.4 7.1 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_6 PF12774.7 CDJ66606.1 - 4.6e-65 219.8 0.0 5.3e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region YmgB PF10798.8 CDJ66606.1 - 0.41 10.5 1.8 3.1 7.7 1.8 2.3 1 1 0 1 1 1 0 Biofilm development protein YmgB/AriR AAA_6 PF12774.7 CDJ66607.1 - 2.1e-62 211.0 0.2 2.9e-62 210.6 0.2 1.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CDJ66607.1 - 0.0035 17.3 0.0 0.15 12.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ66607.1 - 0.0036 17.7 0.0 0.009 16.4 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ66607.1 - 0.092 13.0 0.9 0.16 12.2 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDJ66607.1 - 0.098 13.2 0.1 0.25 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ66607.1 - 0.1 12.3 0.7 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDJ66607.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DHC_N2 PF08393.13 CDJ66608.1 - 1.1e-96 324.5 9.4 1.5e-96 323.9 9.4 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Rx_N PF18052.1 CDJ66608.1 - 0.096 13.0 3.6 0.26 11.6 0.1 3.2 3 0 0 3 3 3 0 Rx N-terminal domain Cag12 PF13117.6 CDJ66608.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Cag pathogenicity island protein Cag12 Plasmid_RAQPRD PF09686.10 CDJ66608.1 - 1.3 9.3 5.1 3.5 7.9 0.0 3.6 4 0 0 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) RHH_1 PF01402.21 CDJ66608.1 - 3.6 7.7 6.5 0.89 9.6 0.0 3.3 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family CdvA PF18822.1 CDJ66610.1 - 0.015 15.1 2.0 0.015 15.1 2.0 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Snapin_Pallidin PF14712.6 CDJ66610.1 - 0.04 14.3 5.0 1.7 9.1 0.9 2.7 2 0 0 2 2 2 0 Snapin/Pallidin Exonuc_VII_L PF02601.15 CDJ66610.1 - 0.041 13.5 9.3 0.055 13.0 9.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rx_N PF18052.1 CDJ66610.1 - 0.2 12.0 7.4 0.66 10.3 0.6 2.7 3 0 0 3 3 3 0 Rx N-terminal domain DUF16 PF01519.16 CDJ66610.1 - 0.86 10.1 8.6 1.4 9.4 1.5 2.3 1 1 0 2 2 2 0 Protein of unknown function DUF16 SYF2 PF08231.12 CDJ66610.1 - 0.95 9.9 5.3 1.6 9.1 5.3 1.4 1 0 0 1 1 1 0 SYF2 splicing factor Baculo_PEP_C PF04513.12 CDJ66610.1 - 3.3 7.8 9.4 50 3.9 7.5 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Usp PF00582.26 CDJ66610.1 - 6.2 7.3 10.2 0.46 11.0 4.2 2.0 1 1 1 2 2 2 0 Universal stress protein family NAD_binding_3 PF03447.16 CDJ66611.1 - 0.18 12.4 0.5 0.37 11.4 0.5 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Nucleoporin_N PF08801.11 CDJ66612.1 - 0.024 13.4 0.1 0.098 11.4 0.0 2.0 2 1 1 3 3 3 0 Nup133 N terminal like DUF4394 PF14339.6 CDJ66612.1 - 0.15 11.4 0.0 6.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4394) Filament PF00038.21 CDJ66613.1 - 0.0016 18.1 30.5 0.0016 18.1 30.5 6.7 1 1 6 8 8 8 2 Intermediate filament protein CdiI_3 PF18616.1 CDJ66615.1 - 2.1 8.3 4.1 17 5.4 0.0 3.3 4 0 0 4 4 4 0 CDI immunity proteins SpoU_sub_bind PF08032.12 CDJ66616.1 - 0.029 14.7 1.4 0.064 13.5 0.6 1.9 1 1 1 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF4618 PF15397.6 CDJ66616.1 - 0.034 13.6 12.0 0.043 13.2 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) BOP1NT PF08145.12 CDJ66616.1 - 0.048 13.6 1.9 0.059 13.3 1.9 1.1 1 0 0 1 1 1 0 BOP1NT (NUC169) domain USP8_interact PF08941.10 CDJ66616.1 - 0.86 9.4 7.7 0.25 11.1 4.6 1.6 1 1 1 2 2 2 0 USP8 interacting V_ATPase_I PF01496.19 CDJ66616.1 - 1.9 6.3 8.6 2.3 6.0 8.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapB PF06005.12 CDJ66616.1 - 3.2 8.2 19.5 1.1 9.8 7.4 2.8 1 1 1 2 2 2 0 Cell division protein ZapB TPR_19 PF14559.6 CDJ66617.1 - 1.6e-08 34.9 0.9 0.026 15.0 0.0 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ66617.1 - 3.1e-07 30.6 2.1 0.34 11.2 0.0 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ66617.1 - 3.1e-06 27.5 0.9 0.046 14.6 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ66617.1 - 2.5e-05 24.0 8.1 0.0027 17.7 0.1 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR_1 PF12854.7 CDJ66617.1 - 3.7e-05 23.3 1.7 0.25 11.1 0.0 3.5 3 0 0 3 3 3 1 PPR repeat TPR_6 PF13174.6 CDJ66617.1 - 8.4e-05 23.0 1.1 0.0017 18.9 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ66617.1 - 0.0002 21.5 6.7 0.15 12.3 0.4 3.1 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 CDJ66617.1 - 0.00027 21.0 2.1 0.65 10.4 0.0 4.1 4 0 0 4 4 4 2 PPR repeat TPR_1 PF00515.28 CDJ66617.1 - 0.0039 16.9 6.5 0.54 10.2 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ66617.1 - 0.059 13.3 0.1 23 5.0 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ66617.1 - 0.12 13.0 0.0 0.5 11.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_3 PF07720.12 CDJ66617.1 - 0.22 11.6 3.2 0.58 10.2 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4006 PF13179.6 CDJ66619.1 - 0.24 11.3 1.2 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF4006) CDRT4 PF15213.6 CDJ66620.1 - 0.022 15.4 0.2 0.022 15.4 0.2 2.9 2 1 1 3 3 3 0 CMT1A duplicated region transcript 4 protein ISP1_C PF18161.1 CDJ66622.1 - 2.6e-13 49.9 0.0 3.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ISP1 C-terminal ISP3_C PF18045.1 CDJ66622.1 - 3.4e-13 49.4 0.0 4.4e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 ISP3 C-terminal TFIIA PF03153.13 CDJ66623.1 - 7.5 6.4 25.0 10 6.0 25.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Filament_head PF04732.14 CDJ66624.1 - 0.057 14.3 18.1 3.9 8.4 14.6 2.6 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Apt1 PF10351.9 CDJ66624.1 - 0.063 12.1 3.5 0.073 11.9 3.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF5320 PF17253.2 CDJ66624.1 - 0.092 13.8 0.1 0.25 12.4 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5320) PUD1_2 PF18457.1 CDJ66624.1 - 0.39 10.7 0.1 0.39 10.7 0.1 3.3 2 1 0 2 2 2 0 Up-Regulated in long-lived daf-2 POX PF07526.11 CDJ66624.1 - 0.73 10.4 8.9 0.11 13.0 2.8 2.3 2 0 0 2 2 2 0 Associated with HOX AAA_11 PF13086.6 CDJ66626.1 - 3e-51 174.7 2.6 4.4e-37 128.3 1.6 9.5 8 2 0 8 8 8 2 AAA domain AAA_12 PF13087.6 CDJ66626.1 - 4e-46 157.2 1.3 3e-45 154.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CDJ66626.1 - 4.6e-07 30.3 0.0 7.6e-05 23.1 0.1 3.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDJ66626.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.8 4 1 0 4 4 4 0 AAA domain AAA PF00004.29 CDJ66626.1 - 0.52 10.7 3.4 0.3 11.5 0.1 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) His_Phos_1 PF00300.22 CDJ66627.1 - 1.5e-05 24.8 9.5 0.074 12.7 0.1 4.4 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) VESA1_N PF12785.7 CDJ66627.1 - 1.5 7.7 8.8 2.5 7.0 8.8 1.3 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 RskA PF10099.9 CDJ66627.1 - 2 8.7 0.0 0.5 10.7 4.3 4.8 3 1 1 4 4 4 0 Anti-sigma-K factor rskA Pro_isomerase PF00160.21 CDJ66628.1 - 3.3e-34 118.4 0.0 7.5e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SYF2 PF08231.12 CDJ66628.1 - 7.8e-29 101.1 2.5 7.8e-29 101.1 2.5 4.0 2 2 1 3 3 3 1 SYF2 splicing factor Ribosomal_L3 PF00297.22 CDJ66629.1 - 3.8e-12 45.9 3.7 9.3e-10 38.0 1.4 3.0 2 1 1 3 3 3 3 Ribosomal protein L3 ubiquitin PF00240.23 CDJ66630.1 - 1.4e-06 28.0 0.0 3.3e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ66630.1 - 0.00094 19.0 0.0 0.0057 16.5 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Exosortase_EpsH PF09721.10 CDJ66630.1 - 0.0045 16.6 0.9 0.0052 16.3 0.9 1.1 1 0 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) DUF237 PF03072.14 CDJ66630.1 - 0.15 12.1 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF237) ParD_antitoxin PF03693.14 CDJ66630.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH SR-25 PF10500.9 CDJ66631.1 - 0.00088 18.9 14.0 0.0011 18.6 14.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF1282 PF06930.12 CDJ66631.1 - 0.15 11.8 6.5 0.2 11.4 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) CDC45 PF02724.14 CDJ66631.1 - 0.3 9.3 11.3 0.38 9.0 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 CDJ66631.1 - 0.97 6.5 7.4 1.1 6.3 7.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Stevor PF17410.2 CDJ66631.1 - 1.2 8.6 6.3 2.5 7.6 6.3 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Nop53 PF07767.11 CDJ66631.1 - 2.4 7.5 18.2 2.8 7.3 18.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) XAP5 PF04921.14 CDJ66631.1 - 5.3 6.8 9.1 8.1 6.2 9.1 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator Tox-WTIP PF15654.6 CDJ66632.1 - 1.9 9.0 7.1 3 8.3 0.0 3.4 2 1 1 3 3 3 0 Toxin with a conserved tryptophan and TIP tripeptide motif ABATE PF07336.11 CDJ66633.1 - 2.5 8.8 22.0 8.6 7.0 15.8 2.4 2 0 0 2 2 2 0 Putative stress-induced transcription regulator DUF3446 PF11928.8 CDJ66633.1 - 2.6 8.4 10.8 0.31 11.4 1.1 2.6 3 0 0 3 3 3 0 Early growth response N-terminal domain LSM PF01423.22 CDJ66634.1 - 3.7e-19 68.2 0.1 4.2e-19 68.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain MMS22L_C PF14911.6 CDJ66634.1 - 0.094 11.8 0.0 0.096 11.8 0.0 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal FAM92 PF06730.11 CDJ66635.1 - 0.16 11.3 2.2 0.19 11.1 2.2 1.0 1 0 0 1 1 1 0 FAM92 protein WD40 PF00400.32 CDJ66636.1 - 5e-08 33.5 0.1 0.012 16.5 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ66636.1 - 6.9e-05 23.1 0.0 0.054 13.8 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain SOG2 PF10428.9 CDJ66636.1 - 1.4 8.0 23.9 1.3 8.2 7.8 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein CAF1 PF04857.20 CDJ66637.1 - 5.5e-28 98.0 7.9 5.5e-28 98.0 7.9 3.0 3 1 0 3 3 3 1 CAF1 family ribonuclease DUF966 PF06136.13 CDJ66637.1 - 0.0027 17.5 47.4 0.062 13.0 25.8 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF966) DUF755 PF05501.11 CDJ66637.1 - 0.009 16.3 21.4 0.009 16.3 21.4 5.2 3 1 2 5 5 3 2 Domain of unknown function (DUF755) TFIIA PF03153.13 CDJ66637.1 - 0.034 14.1 38.0 0.032 14.2 25.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 CDJ66637.1 - 0.044 12.4 27.6 0.43 9.2 13.2 2.3 2 0 0 2 2 2 0 Hamartin protein FB_lectin PF07367.11 CDJ66637.1 - 0.18 11.7 1.0 0.43 10.5 1.0 1.6 1 0 0 1 1 1 0 Fungal fruit body lectin GREB1 PF15782.5 CDJ66637.1 - 0.18 8.9 38.1 0.12 9.5 21.7 2.1 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer FAM196 PF15265.6 CDJ66637.1 - 0.88 9.0 37.2 0.15 11.5 8.1 2.1 2 0 0 2 2 2 0 FAM196 family CDC45 PF02724.14 CDJ66637.1 - 0.9 7.8 30.5 0.83 7.9 10.3 2.2 2 0 0 2 2 2 0 CDC45-like protein Mitofilin PF09731.9 CDJ66637.1 - 3.3 6.4 39.1 3.7 6.3 12.4 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein RIFIN PF02009.16 CDJ66637.1 - 5.3 6.8 18.8 4.5 7.1 9.8 2.5 2 0 0 2 2 2 0 Rifin Peptidase_S64 PF08192.11 CDJ66637.1 - 6.7 5.1 33.2 1.1 7.7 7.8 2.2 2 0 0 2 2 2 0 Peptidase family S64 BAF1_ABF1 PF04684.13 CDJ66637.1 - 8.2 5.4 39.3 2.8 6.9 16.2 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF572 PF04502.13 CDJ66637.1 - 9.8 5.7 38.6 2.2 7.8 8.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) SARAF PF06682.12 CDJ66638.1 - 0.23 11.0 0.0 0.23 11.0 0.0 10.7 6 5 2 9 9 9 0 SOCE-associated regulatory factor of calcium homoeostasis Mito_carr PF00153.27 CDJ66638.1 - 1 9.3 8.7 7.6 6.5 0.1 4.9 3 0 0 3 3 3 0 Mitochondrial carrier protein SUIM_assoc PF16619.5 CDJ66640.1 - 2e-05 24.5 39.0 0.032 14.3 8.2 4.3 3 1 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 DUF4667 PF15700.5 CDJ66640.1 - 0.013 15.6 24.4 0.038 14.1 1.4 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ66642.1 - 0.002 17.8 3.5 0.002 17.8 3.5 17.3 15 1 2 17 17 17 7 Nuclear RNA-splicing-associated protein PC_rep PF01851.22 CDJ66642.1 - 0.003 17.9 3.4 0.68 10.5 0.3 3.0 2 0 0 2 2 2 2 Proteasome/cyclosome repeat PC_rep PF01851.22 CDJ66643.1 - 0.0019 18.6 0.1 0.37 11.3 0.0 3.5 3 0 0 3 3 3 1 Proteasome/cyclosome repeat RskA PF10099.9 CDJ66643.1 - 0.018 15.3 0.0 0.018 15.3 0.0 7.8 3 3 2 6 6 6 0 Anti-sigma-K factor rskA TMEM251 PF15190.6 CDJ66643.1 - 0.58 10.1 3.8 0.78 9.7 1.5 2.4 2 0 0 2 2 2 0 Transmembrane protein 251 SUZ PF12752.7 CDJ66643.1 - 1.1 10.0 8.1 59 4.5 0.1 3.9 3 0 0 3 3 3 0 SUZ domain VMA21 PF09446.10 CDJ66644.1 - 0.0002 21.4 0.4 0.0002 21.4 0.4 1.7 2 0 0 2 2 1 1 VMA21-like domain Connexin PF00029.19 CDJ66644.1 - 0.0015 18.4 3.3 0.0015 18.4 3.3 1.5 1 1 1 2 2 2 1 Connexin Claudin_2 PF13903.6 CDJ66644.1 - 0.0018 18.1 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction AIF_C PF14721.6 CDJ66644.1 - 0.0035 17.7 2.1 0.0035 17.7 2.1 2.0 2 0 0 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term SpoIIP PF07454.11 CDJ66644.1 - 0.0057 16.2 2.0 0.0057 16.2 2.0 1.5 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) Folate_carrier PF01770.18 CDJ66644.1 - 0.0062 15.3 0.4 0.0072 15.1 0.4 1.2 1 0 0 1 1 1 1 Reduced folate carrier Eapp_C PF10238.9 CDJ66644.1 - 0.0063 16.6 1.2 0.0063 16.6 1.2 1.9 2 0 0 2 2 2 1 E2F-associated phosphoprotein Mlh1_C PF16413.5 CDJ66644.1 - 0.0082 15.5 2.3 0.0082 15.5 2.3 1.4 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus RED_N PF07808.13 CDJ66644.1 - 0.0083 15.7 3.7 0.0083 15.7 3.7 1.8 2 0 0 2 2 2 1 RED-like protein N-terminal region DUF4770 PF15994.5 CDJ66644.1 - 0.011 16.0 3.1 0.011 16.0 3.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Ctr PF04145.15 CDJ66644.1 - 0.012 16.2 8.5 1.4 9.5 4.1 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Suf PF05843.14 CDJ66644.1 - 0.012 15.6 7.7 0.012 15.6 7.7 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Sarcoglycan_2 PF05510.13 CDJ66644.1 - 0.016 14.0 0.3 0.019 13.8 0.3 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon AUX_IAA PF02309.16 CDJ66644.1 - 0.027 14.3 0.6 0.039 13.8 0.6 1.3 1 1 0 1 1 1 0 AUX/IAA family Anoctamin PF04547.12 CDJ66644.1 - 0.055 12.3 0.3 0.071 11.9 0.3 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF674 PF05056.12 CDJ66644.1 - 0.072 11.9 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) CLN3 PF02487.17 CDJ66644.1 - 0.098 11.7 3.4 0.046 12.8 1.3 1.5 2 0 0 2 2 2 0 CLN3 protein BatD PF13584.6 CDJ66644.1 - 0.11 11.3 12.2 0.44 9.3 12.0 1.8 1 1 0 1 1 1 0 Oxygen tolerance HCO3_cotransp PF00955.21 CDJ66644.1 - 0.14 11.0 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family Otopetrin PF03189.13 CDJ66644.1 - 0.14 11.0 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Otopetrin PTS_EIIC PF02378.18 CDJ66644.1 - 0.19 10.7 2.2 0.31 10.0 2.2 1.3 1 0 0 1 1 1 0 Phosphotransferase system, EIIC FAM176 PF14851.6 CDJ66644.1 - 0.23 11.1 5.2 3.2 7.4 6.6 1.9 2 0 0 2 2 2 0 FAM176 family Hid1 PF12722.7 CDJ66644.1 - 0.23 9.5 4.1 0.31 9.1 4.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rxt3 PF08642.10 CDJ66644.1 - 0.24 12.2 2.3 0.4 11.5 1.0 1.9 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 WASH-7_C PF14746.6 CDJ66644.1 - 0.31 10.7 8.7 56 3.4 0.0 2.1 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Dmrt1 PF12374.8 CDJ66644.1 - 0.38 11.2 2.1 0.61 10.6 1.2 1.8 2 0 0 2 2 1 0 Double-sex mab3 related transcription factor 1 EOS1 PF12326.8 CDJ66644.1 - 0.63 9.9 3.6 0.62 10.0 1.9 1.8 2 0 0 2 2 2 0 N-glycosylation protein TFIIA PF03153.13 CDJ66644.1 - 0.66 9.9 31.4 0.45 10.4 22.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 CDJ66644.1 - 1.4 9.1 12.3 0.66 10.1 6.3 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Scs3p PF10261.9 CDJ66644.1 - 1.9 7.9 4.8 1.9 8.0 3.5 1.6 1 1 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM Orf78 PF06024.12 CDJ66644.1 - 2.1 8.7 6.2 0.4 11.0 0.7 2.4 2 1 1 3 3 3 0 Orf78 (ac78) Peroxin-13_N PF04088.13 CDJ66644.1 - 7.7 6.8 8.7 25 5.1 7.2 2.0 2 0 0 2 2 2 0 Peroxin 13, N-terminal region V_ATPase_I PF01496.19 CDJ66644.1 - 8.4 4.2 12.4 6.8 4.5 10.3 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF5327 PF17261.2 CDJ66644.1 - 9.1 7.1 19.8 6.4 7.6 14.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5327) AF-4 PF05110.13 CDJ66645.1 - 0.58 8.2 30.2 0.18 9.8 13.1 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein ALMT PF11744.8 CDJ66645.1 - 3.7 6.3 14.5 1.7 7.4 1.9 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter RAP1 PF07218.11 CDJ66645.1 - 4.4 5.5 11.0 5.5 5.1 11.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RLL PF10036.9 CDJ66645.1 - 8 6.2 24.3 0.042 13.7 0.8 2.9 1 1 2 3 3 3 0 RNA transcription, translation and transport factor protein SmpB PF01668.18 CDJ66646.1 - 0.16 11.9 0.2 0.16 11.9 0.2 2.4 3 0 0 3 3 3 0 SmpB protein Ribonuc_red_sm PF00268.21 CDJ66647.1 - 2e-80 270.2 0.0 2.4e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Surface_antigen PF11054.8 CDJ66648.1 - 1.7e-57 194.9 1.6 2e-57 194.7 1.6 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ66649.1 - 5e-62 209.7 2.6 7.6e-62 209.1 2.6 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Aminotran_1_2 PF00155.21 CDJ66650.1 - 3.3e-15 56.1 0.6 2.4e-14 53.3 0.6 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II DUF1645 PF07816.11 CDJ66650.1 - 0.019 15.5 3.9 0.019 15.5 3.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) TFIIA PF03153.13 CDJ66650.1 - 2.6 7.9 31.3 1.4 8.8 10.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ66650.1 - 4.6 7.9 12.3 7.3 7.3 9.2 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ66652.1 - 0.0051 17.1 6.3 0.0051 17.1 6.3 3.5 1 1 2 3 3 3 2 Anti-sigma-K factor rskA DSHCT PF08148.12 CDJ66652.1 - 0.043 13.5 0.2 0.099 12.3 0.2 1.6 1 0 0 1 1 1 0 DSHCT (NUC185) domain Gaa1 PF04114.14 CDJ66652.1 - 0.074 12.1 0.2 0.094 11.7 0.2 1.3 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Ribosomal_60s PF00428.19 CDJ66652.1 - 9.9 6.8 32.2 0.38 11.4 1.3 4.7 5 0 0 5 5 5 0 60s Acidic ribosomal protein Cytochrom_C PF00034.21 CDJ66653.1 - 2.3e-12 47.8 0.0 3e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CDJ66653.1 - 5.7e-06 26.6 2.6 1.4e-05 25.3 2.6 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CDJ66653.1 - 0.0034 17.1 0.0 0.0085 15.8 0.0 1.6 2 0 0 2 2 2 1 Cytochrome c-550 domain Haem_bd PF14376.6 CDJ66653.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Haem-binding domain Ferrochelatase PF00762.19 CDJ66655.1 - 1.2e-66 224.9 0.0 4.4e-66 223.1 0.0 1.8 1 1 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 CDJ66655.1 - 0.22 11.9 1.5 2.2 8.7 0.0 2.7 3 0 0 3 3 3 0 CbiX SelP_N PF04592.14 CDJ66655.1 - 1.2 8.5 11.0 2 7.7 11.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Vac7 PF12751.7 CDJ66655.1 - 7.5 5.9 9.0 11 5.3 9.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Kinesin PF00225.23 CDJ66656.1 - 2.2e-105 352.3 0.2 3.2e-105 351.8 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ66656.1 - 2.4e-26 92.5 0.0 5.6e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DKCLD PF08068.12 CDJ66657.1 - 2.6e-27 94.6 0.1 6.1e-27 93.5 0.1 1.7 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.18 CDJ66657.1 - 1.1e-24 87.6 0.8 9.2e-22 78.0 0.8 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 CDJ66657.1 - 1.9e-21 75.8 0.9 3.6e-21 74.9 0.9 1.5 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 CDJ66657.1 - 1e-20 73.6 0.7 1.7e-20 72.9 0.7 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UPF0113 PF03657.13 CDJ66657.1 - 0.0032 17.7 0.1 0.01 16.1 0.0 1.9 2 0 0 2 2 2 1 UPF0113 PUA domain Coilin_N PF15862.5 CDJ66657.1 - 4.2 7.2 10.5 8.6 6.2 10.5 1.5 1 0 0 1 1 1 0 Coilin N-terminus Evr1_Alr PF04777.13 CDJ66660.1 - 1.8e-08 34.7 2.4 1.3e-05 25.6 1.6 3.5 2 1 0 2 2 2 2 Erv1 / Alr family Thioredoxin PF00085.20 CDJ66660.1 - 3.3e-08 33.4 0.0 6.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CDJ66660.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Zn_Tnp_IS1595 PF12760.7 CDJ66660.1 - 1.8 8.6 9.8 1.2 9.2 0.6 3.9 5 0 0 5 5 5 0 Transposase zinc-ribbon domain DnaJ_C PF01556.18 CDJ66662.1 - 1.9e-35 122.2 0.1 2.9e-35 121.5 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ66662.1 - 2e-24 85.5 1.1 4.1e-24 84.5 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDJ66662.1 - 0.042 14.2 3.8 0.098 13.0 3.8 1.5 1 0 0 1 1 1 0 DnaJ central domain TB PF00683.17 CDJ66662.1 - 0.11 12.3 0.5 0.23 11.2 0.5 1.5 1 0 0 1 1 1 0 TB domain VPS9 PF02204.18 CDJ66663.1 - 0.00079 19.6 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PLDc PF00614.22 CDJ66666.1 - 7.4e-06 25.9 0.2 1.8e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Phospholipase D Active site motif PLDc_2 PF13091.6 CDJ66666.1 - 0.00012 21.9 0.0 0.00034 20.5 0.0 1.8 1 1 0 1 1 1 1 PLD-like domain SUIM_assoc PF16619.5 CDJ66666.1 - 0.00039 20.4 13.3 0.021 14.9 0.6 2.5 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ66666.1 - 0.052 13.2 13.4 0.66 9.5 0.5 2.1 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ66666.1 - 0.68 9.5 20.0 0.059 13.0 13.7 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Shadoo PF14999.6 CDJ66666.1 - 1.1 9.4 21.3 0.071 13.2 6.4 2.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF2722 PF10846.8 CDJ66666.1 - 1.4 7.7 11.0 2.7 6.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) KCNQ2_u3 PF16642.5 CDJ66666.1 - 3.7 8.6 10.3 26 5.9 0.2 2.5 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 PmbA_TldD PF01523.16 CDJ66666.1 - 4.8 6.9 8.6 19 5.0 0.0 2.4 1 1 0 2 2 2 0 Putative modulator of DNA gyrase DUF4179 PF13786.6 CDJ66666.1 - 6.1 7.4 6.4 11 6.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DAGAT PF03982.13 CDJ66667.1 - 1.2e-61 208.2 0.0 1.8e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Utp14 PF04615.13 CDJ66667.1 - 0.03 12.9 19.5 0.038 12.6 19.5 1.1 1 0 0 1 1 1 0 Utp14 protein FHIPEP PF00771.20 CDJ66667.1 - 0.58 8.6 7.0 0.95 7.8 7.0 1.2 1 0 0 1 1 1 0 FHIPEP family DUF4683 PF15735.5 CDJ66667.1 - 0.79 9.3 16.8 1.5 8.3 16.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) Phostensin_N PF13916.6 CDJ66667.1 - 1.3 9.4 10.0 0.35 11.2 1.9 2.9 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal RRM_1 PF00076.22 CDJ66668.1 - 4.2e-22 77.8 0.2 2.8e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ66668.1 - 2.1e-11 43.5 0.0 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ66668.1 - 5.3e-09 35.7 0.0 3.2e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ66668.1 - 4e-05 23.5 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CDJ66668.1 - 0.0064 16.5 0.1 3 8.0 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Calcipressin PF04847.12 CDJ66668.1 - 0.28 10.9 0.0 0.28 10.9 0.0 2.9 3 0 0 3 3 3 0 Calcipressin PHM7_cyt PF14703.6 CDJ66668.1 - 0.31 11.3 6.1 0.37 11.0 0.0 2.9 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter GAGA_bind PF06217.12 CDJ66669.1 - 2.7e-05 24.6 1.4 4.2e-05 24.0 1.4 1.2 1 0 0 1 1 1 1 GAGA binding protein-like family Drc1-Sld2 PF11719.8 CDJ66669.1 - 0.022 14.3 3.3 0.021 14.4 3.3 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Atrophin-1 PF03154.15 CDJ66669.1 - 7 4.8 12.4 8.9 4.5 12.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family Seipin PF06775.14 CDJ66670.1 - 0.0004 20.6 0.1 0.34 11.0 0.0 2.4 2 0 0 2 2 2 2 Putative adipose-regulatory protein (Seipin) Phage_holin_3_6 PF07332.11 CDJ66670.1 - 0.16 12.0 15.9 0.097 12.7 1.4 3.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III RIO1 PF01163.22 CDJ66671.1 - 8.3e-47 159.2 0.3 1.4e-46 158.5 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CDJ66671.1 - 4.8e-33 113.2 0.7 1.2e-32 112.0 0.7 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 CDJ66671.1 - 5.8e-08 33.0 4.3 0.0019 18.1 1.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CDJ66671.1 - 8.6e-07 28.5 1.7 8.3e-06 25.3 0.8 2.4 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CDJ66671.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Hid1 PF12722.7 CDJ66671.1 - 0.094 10.8 7.0 0.13 10.4 7.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1803 PF08820.10 CDJ66671.1 - 0.11 12.5 0.2 0.5 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) Macoilin PF09726.9 CDJ66671.1 - 0.34 9.4 8.7 0.48 8.9 8.7 1.1 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 CDJ66671.1 - 0.38 8.9 19.5 0.35 9.0 17.1 1.8 2 0 0 2 2 2 0 Nop14-like family Raftlin PF15250.6 CDJ66671.1 - 0.7 8.6 8.2 0.95 8.1 8.2 1.1 1 0 0 1 1 1 0 Raftlin DUF2428 PF10350.9 CDJ66671.1 - 3.7 6.7 7.3 9.2 5.4 7.3 1.7 1 1 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) RR_TM4-6 PF06459.12 CDJ66671.1 - 8.5 6.1 12.3 13 5.5 12.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 CDJ66671.1 - 9.8 6.3 7.3 18 5.5 7.3 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal STI1 PF17830.1 CDJ66672.1 - 0.0028 17.5 3.9 0.028 14.4 1.1 2.0 1 1 1 2 2 2 2 STI1 domain GerD PF17898.1 CDJ66672.1 - 0.01 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 Spore germination GerD central core domain Glutaredoxin PF00462.24 CDJ66673.1 - 2e-16 60.0 0.1 2.9e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CDJ66673.1 - 0.00016 21.7 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 CDJ66673.1 - 0.0023 17.7 0.0 0.0029 17.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.14 CDJ66673.1 - 0.012 16.1 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 CDJ66673.1 - 0.017 15.5 0.2 0.032 14.7 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain GST_N_3 PF13417.6 CDJ66673.1 - 0.038 14.4 0.0 0.059 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TraF PF13728.6 CDJ66673.1 - 0.05 13.4 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Ogr_Delta PF04606.12 CDJ66673.1 - 0.052 13.5 0.1 0.052 13.5 0.1 1.7 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger FANCL_C PF11793.8 CDJ66673.1 - 0.13 12.5 0.0 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain DEAD PF00270.29 CDJ66674.1 - 3.1e-38 131.3 0.3 2.6e-37 128.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ66674.1 - 2.7e-17 63.1 5.0 3.9e-11 43.3 0.1 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDJ66674.1 - 2.9e-09 37.0 0.1 7.4e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CDJ66674.1 - 7.8e-05 22.7 0.0 7.8e-05 22.7 0.0 3.2 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit IMS PF00817.20 CDJ66675.1 - 3.9e-31 108.1 0.0 8.2e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 CDJ66675.1 - 4.2e-06 27.1 0.0 0.00097 19.5 0.0 3.4 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain Ashwin PF15323.6 CDJ66677.1 - 0.11 12.5 1.5 0.16 12.0 1.5 1.2 1 0 0 1 1 1 0 Developmental protein SPX PF03105.19 CDJ66677.1 - 0.18 11.7 3.4 0.18 11.7 3.4 1.1 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 CDJ66677.1 - 0.98 9.0 16.4 0.11 12.1 12.3 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Membr_traf_MHD PF10540.9 CDJ66679.1 - 0.3 11.2 0.8 0.92 9.7 0.0 2.0 2 0 0 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain Filament_head PF04732.14 CDJ66679.1 - 1.5 9.8 25.8 4.3 8.3 5.8 3.0 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region CiPC PF15800.5 CDJ66679.1 - 3.3 7.3 19.4 3.9 7.1 10.8 2.4 2 0 0 2 2 2 0 Clock interacting protein circadian SR-25 PF10500.9 CDJ66680.1 - 0.0074 15.9 10.3 0.0074 15.9 10.3 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.16 CDJ66680.1 - 0.071 13.2 6.7 0.1 12.6 6.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MAGE PF01454.19 CDJ66680.1 - 1 9.0 6.3 0.3 10.7 0.1 2.1 2 0 0 2 2 2 0 MAGE family DUF4834 PF16118.5 CDJ66680.1 - 4.8 8.2 9.4 30 5.7 4.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Ribosomal_60s PF00428.19 CDJ66680.1 - 7.7 7.2 9.5 3.7 8.2 3.2 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein CNOT1_HEAT PF16418.5 CDJ66680.1 - 8.4 6.5 11.2 0.76 9.8 1.8 2.2 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Gar1 PF04410.14 CDJ66681.1 - 2.3e-13 50.2 2.9 7.9e-13 48.5 2.9 1.8 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region LMBR1 PF04791.16 CDJ66681.1 - 0.0035 16.3 0.0 0.0036 16.3 0.0 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF2956 PF11169.8 CDJ66681.1 - 0.0036 17.5 9.0 0.0052 17.0 9.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2956) Synuclein PF01387.17 CDJ66681.1 - 0.02 15.1 1.9 0.02 15.1 1.9 1.3 1 1 0 1 1 1 0 Synuclein Exonuc_VII_L PF02601.15 CDJ66681.1 - 0.038 13.6 6.9 0.049 13.2 6.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MRP-S31 PF15433.6 CDJ66681.1 - 0.042 13.5 6.6 0.052 13.2 6.6 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 TFIIA PF03153.13 CDJ66681.1 - 0.13 12.3 20.0 0.15 12.0 20.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S15 PF02129.18 CDJ66681.1 - 0.18 11.4 2.4 0.21 11.1 2.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LCIB_C_CA PF18599.1 CDJ66681.1 - 0.34 10.2 2.3 0.45 9.8 2.3 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases MSP1b PF03429.13 CDJ66681.1 - 0.56 8.2 11.8 0.88 7.6 11.8 1.3 1 0 0 1 1 1 0 Major surface protein 1B SprA-related PF12118.8 CDJ66681.1 - 1.6 7.8 16.1 2 7.5 16.1 1.1 1 0 0 1 1 1 0 SprA-related family FAM222A PF15258.6 CDJ66681.1 - 2.4 7.1 14.0 2.7 7.0 14.0 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Presenilin PF01080.17 CDJ66681.1 - 7.8 5.1 7.4 9 4.9 7.4 1.1 1 0 0 1 1 1 0 Presenilin Adaptin_N PF01602.20 CDJ66683.1 - 0.071 11.7 0.1 0.078 11.5 0.1 1.0 1 0 0 1 1 1 0 Adaptin N terminal region CAP_N PF01213.19 CDJ66683.1 - 0.11 12.0 2.4 0.12 11.8 2.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NICE-1 PF15845.5 CDJ66683.1 - 0.21 12.4 7.7 0.27 12.0 7.7 1.1 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family RskA PF10099.9 CDJ66683.1 - 2.3 8.5 23.0 2.4 8.4 23.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3597 PF12200.8 CDJ66684.1 - 2.1 8.9 7.1 2.9 8.4 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Surface_antigen PF11054.8 CDJ66685.1 - 7.7e-18 65.1 4.6 4e-16 59.4 4.6 2.0 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen RskA PF10099.9 CDJ66686.1 - 0.25 11.6 16.7 0.43 10.8 16.7 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ66686.1 - 3.9 8.1 17.8 0.15 12.7 10.3 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3138 PF11336.8 CDJ66686.1 - 6.3 5.3 11.1 9 4.8 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MBOAT PF03062.19 CDJ66688.1 - 2.8e-28 99.3 14.5 4.3e-28 98.7 14.5 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CDJ66688.1 - 0.00041 20.6 4.3 0.0015 18.7 4.5 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RskA PF10099.9 CDJ66688.1 - 0.24 11.7 11.6 0.44 10.8 11.6 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SRTM1 PF15872.5 CDJ66688.1 - 1.1 9.4 6.4 1 9.5 0.5 2.7 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Peptidase_S49_N PF08496.10 CDJ66690.1 - 0.024 14.7 11.2 0.028 14.5 11.2 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2232 PF09991.9 CDJ66690.1 - 0.05 12.8 3.8 0.062 12.5 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SID-1_RNA_chan PF13965.6 CDJ66690.1 - 0.071 11.5 3.3 0.079 11.4 3.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ArsP_2 PF11449.8 CDJ66690.1 - 0.083 12.1 4.3 0.099 11.8 4.3 1.1 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter HA2 PF04408.23 CDJ66690.1 - 0.096 13.0 7.8 0.13 12.6 7.8 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) Connexin PF00029.19 CDJ66690.1 - 0.18 11.5 10.0 0.18 11.6 10.0 1.0 1 0 0 1 1 1 0 Connexin DUF5427 PF10310.9 CDJ66690.1 - 0.19 10.7 21.1 0.2 10.6 21.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) BAF1_ABF1 PF04684.13 CDJ66690.1 - 0.31 10.0 17.5 0.39 9.7 17.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor eIF-3_zeta PF05091.12 CDJ66690.1 - 0.38 9.7 19.1 0.36 9.7 19.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.6 CDJ66690.1 - 0.44 10.5 10.7 0.47 10.4 10.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A OATP PF03137.20 CDJ66690.1 - 0.5 8.6 7.4 0.56 8.4 7.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RR_TM4-6 PF06459.12 CDJ66690.1 - 0.7 9.7 17.0 0.78 9.5 17.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glt_symporter PF03616.14 CDJ66690.1 - 0.72 8.5 3.7 0.9 8.1 3.7 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter Coilin_N PF15862.5 CDJ66690.1 - 0.77 9.6 16.8 0.95 9.3 16.8 1.3 1 0 0 1 1 1 0 Coilin N-terminus Serinc PF03348.15 CDJ66690.1 - 0.86 8.5 8.8 0.97 8.3 8.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) CobT PF06213.12 CDJ66690.1 - 0.88 8.9 23.7 1 8.7 23.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ctr PF04145.15 CDJ66690.1 - 0.94 10.1 8.1 1.1 9.8 8.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family EOS1 PF12326.8 CDJ66690.1 - 0.97 9.3 7.8 1.1 9.2 7.8 1.1 1 0 0 1 1 1 0 N-glycosylation protein CPSF100_C PF13299.6 CDJ66690.1 - 0.98 9.6 12.8 1.2 9.3 12.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 CDJ66690.1 - 1 8.3 13.8 1.1 8.3 13.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PPL5 PF18168.1 CDJ66690.1 - 1.1 8.5 8.2 1.1 8.5 8.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 SARAF PF06682.12 CDJ66690.1 - 1.1 8.8 16.8 1.2 8.7 16.8 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis FAM176 PF14851.6 CDJ66690.1 - 1.1 8.9 7.6 1.2 8.7 7.6 1.2 1 0 0 1 1 1 0 FAM176 family Pex14_N PF04695.13 CDJ66690.1 - 1.3 9.6 32.9 2 9.1 32.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Folate_carrier PF01770.18 CDJ66690.1 - 1.3 7.6 6.9 1.3 7.7 6.9 1.2 1 0 0 1 1 1 0 Reduced folate carrier Baculo_PP31 PF05311.11 CDJ66690.1 - 1.4 8.4 14.0 1.5 8.3 14.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Nucleoside_tran PF01733.18 CDJ66690.1 - 1.4 8.2 3.5 1.4 8.2 3.5 1.1 1 0 0 1 1 1 0 Nucleoside transporter ORC_WH_C PF18137.1 CDJ66690.1 - 1.6 8.8 12.3 1.8 8.6 12.3 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Tim54 PF11711.8 CDJ66690.1 - 1.7 7.4 15.3 1.9 7.2 15.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BORG_CEP PF14957.6 CDJ66690.1 - 1.7 9.8 11.3 2 9.6 11.3 1.1 1 0 0 1 1 1 0 Cdc42 effector SpoIIP PF07454.11 CDJ66690.1 - 1.8 7.9 18.3 2.1 7.7 18.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CLN3 PF02487.17 CDJ66690.1 - 1.8 7.5 11.1 1.9 7.4 11.1 1.1 1 0 0 1 1 1 0 CLN3 protein Spc7_N PF15402.6 CDJ66690.1 - 2.1 6.5 17.1 2.3 6.3 17.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Zip PF02535.22 CDJ66690.1 - 2.5 7.2 11.3 2.9 7.0 11.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 CDJ66690.1 - 2.6 7.5 10.1 2.8 7.4 10.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DDHD PF02862.17 CDJ66690.1 - 2.6 8.2 16.0 2.9 8.0 16.0 1.1 1 0 0 1 1 1 0 DDHD domain NEMP PF10225.9 CDJ66690.1 - 2.7 7.6 5.6 2.9 7.5 5.6 1.1 1 0 0 1 1 1 0 NEMP family HemX PF04375.14 CDJ66690.1 - 2.7 7.2 34.9 3 7.1 34.9 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3408 PF11888.8 CDJ66690.1 - 2.8 8.1 18.0 3.4 7.8 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Presenilin PF01080.17 CDJ66690.1 - 3 6.5 21.6 3.2 6.4 21.6 1.0 1 0 0 1 1 1 0 Presenilin O-antigen_lig PF13425.6 CDJ66690.1 - 3.3 6.4 4.4 3.5 6.3 4.4 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF2828 PF11443.8 CDJ66690.1 - 3.4 5.7 15.1 3.5 5.6 15.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.16 CDJ66690.1 - 3.5 7.6 12.7 3.8 7.5 12.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2370 PF10176.9 CDJ66690.1 - 3.5 7.2 9.6 3.7 7.1 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF913 PF06025.12 CDJ66690.1 - 3.8 6.4 11.6 4.1 6.3 11.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) HCO3_cotransp PF00955.21 CDJ66690.1 - 4.3 6.1 6.6 4.4 6.0 6.6 1.0 1 0 0 1 1 1 0 HCO3- transporter family PAT1 PF09770.9 CDJ66690.1 - 4.6 5.4 34.3 5.4 5.2 34.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gti1_Pac2 PF09729.9 CDJ66690.1 - 4.9 7.2 13.0 5.5 7.0 13.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family CSG2 PF16965.5 CDJ66690.1 - 5.1 5.9 7.9 5.2 5.9 7.9 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator DUF1980 PF09323.10 CDJ66690.1 - 5.2 6.9 13.1 6.2 6.7 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Peptidase_S15 PF02129.18 CDJ66690.1 - 5.3 6.5 18.2 6.2 6.3 18.2 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Paramyxo_ncap PF00973.19 CDJ66690.1 - 5.4 5.8 13.8 6.3 5.6 13.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Suf PF05843.14 CDJ66690.1 - 5.4 6.9 24.6 6.4 6.7 24.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM199X PF15814.5 CDJ66690.1 - 5.8 5.9 10.8 6.6 5.7 10.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X Hid1 PF12722.7 CDJ66690.1 - 5.9 4.9 15.7 6.1 4.8 15.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SelP_N PF04592.14 CDJ66690.1 - 6.6 6.1 19.8 7.4 5.9 19.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TMEM174 PF15029.6 CDJ66690.1 - 7 6.3 11.7 7.5 6.2 11.7 1.0 1 0 0 1 1 1 0 Transmembrane protein 174 DUF2464 PF10240.9 CDJ66690.1 - 7.5 6.0 14.8 8.5 5.9 14.8 1.0 1 0 0 1 1 1 0 Multivesicular body subunit 12 ALMT PF11744.8 CDJ66690.1 - 8.1 5.1 11.5 8.4 5.1 11.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Velvet PF11754.8 CDJ66690.1 - 8.4 6.2 21.2 9.2 6.1 21.2 1.0 1 0 0 1 1 1 0 Velvet factor Gastrin PF00918.17 CDJ66690.1 - 8.7 7.3 13.1 12 6.9 13.1 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF3464 PF11947.8 CDJ66690.1 - 8.7 6.1 19.2 13 5.5 19.2 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Membralin PF09746.9 CDJ66690.1 - 8.8 5.2 8.7 9.5 5.1 8.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein Band_3_cyto PF07565.13 CDJ66690.1 - 9.1 6.0 15.9 10 5.8 15.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RskA PF10099.9 CDJ66692.1 - 9.7e-05 22.7 0.5 9.7e-05 22.7 0.5 6.6 4 2 1 5 5 5 1 Anti-sigma-K factor rskA PsbI PF02532.14 CDJ66694.1 - 1.1 9.3 3.0 8.7 6.4 2.0 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) LRR19-TM PF15176.6 CDJ66695.1 - 0.0063 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain zf-C2H2_4 PF13894.6 CDJ66696.1 - 0.033 15.0 0.4 0.033 15.0 0.4 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger MAP65_ASE1 PF03999.12 CDJ66697.1 - 0.02 13.6 3.4 0.032 12.9 3.4 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Spore_YhcN_YlaJ PF09580.10 CDJ66698.1 - 0.43 10.6 0.0 0.43 10.6 0.0 6.9 3 3 1 4 4 4 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Actin PF00022.19 CDJ66699.1 - 1.2e-25 90.0 0.0 6.3e-25 87.6 0.0 2.1 2 0 0 2 2 2 1 Actin SPX PF03105.19 CDJ66699.1 - 0.0071 16.3 1.7 0.0071 16.3 1.7 3.4 2 1 0 2 2 2 1 SPX domain Rap1_C PF11626.8 CDJ66699.1 - 0.34 11.0 4.5 15 5.7 0.0 3.3 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3506 PF12014.8 CDJ66699.1 - 0.64 10.0 0.0 0.64 10.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3506) Centro_C10orf90 PF17730.1 CDJ66700.1 - 0.05 12.4 10.6 0.059 12.2 10.6 1.0 1 0 0 1 1 1 0 Centrosomal C10orf90 BAF1_ABF1 PF04684.13 CDJ66700.1 - 2.6 7.0 9.4 3.1 6.7 9.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor EF-hand_8 PF13833.6 CDJ66701.1 - 4.5e-05 23.2 0.1 4.5e-05 23.2 0.1 1.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 CDJ66701.1 - 0.0002 21.8 0.8 0.00026 21.4 0.1 1.6 2 0 0 2 2 2 1 EF-hand domain pair S_100 PF01023.19 CDJ66701.1 - 0.021 14.5 0.7 0.054 13.2 0.6 1.7 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 CDJ66701.1 - 0.047 13.3 0.9 0.85 9.3 0.0 2.5 3 0 0 3 3 3 0 EF hand TFIIA PF03153.13 CDJ66701.1 - 0.048 13.7 11.0 0.045 13.8 11.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MH2 PF03166.14 CDJ66701.1 - 0.051 13.8 1.2 0.056 13.7 1.2 1.1 1 0 0 1 1 1 0 MH2 domain GET2 PF08690.10 CDJ66701.1 - 0.055 13.1 6.2 0.064 12.9 6.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 EF-hand_6 PF13405.6 CDJ66701.1 - 0.074 13.0 0.0 20 5.4 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain DUF1707 PF08044.11 CDJ66701.1 - 0.18 11.9 1.5 1.6 8.8 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1707) Peroxin-13_N PF04088.13 CDJ66701.1 - 0.43 10.8 3.3 0.65 10.3 3.3 1.3 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Presenilin PF01080.17 CDJ66701.1 - 0.59 8.8 2.5 0.53 9.0 2.5 1.1 1 0 0 1 1 1 0 Presenilin Ctr PF04145.15 CDJ66701.1 - 0.85 10.2 2.4 1.4 9.5 2.4 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Spt20 PF12090.8 CDJ66701.1 - 0.88 9.1 19.7 1.2 8.7 19.7 1.2 1 0 0 1 1 1 0 Spt20 family Radial_spoke_3 PF06098.11 CDJ66701.1 - 1.5 8.0 17.0 1.7 7.8 15.9 1.6 1 1 0 1 1 1 0 Radial spoke protein 3 GNAT_acetyltr_2 PF13718.6 CDJ66701.1 - 3.5 7.0 8.6 38 3.6 8.6 2.0 1 1 0 1 1 1 0 GNAT acetyltransferase 2 AAA_23 PF13476.6 CDJ66701.1 - 3.8 8.0 13.0 4.8 7.6 13.0 1.1 1 0 0 1 1 1 0 AAA domain TERB2 PF15101.6 CDJ66701.1 - 9.2 6.3 11.4 12 5.8 11.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NPR1_interact PF15699.5 CDJ66702.1 - 0.0029 18.2 1.7 0.0039 17.8 1.7 1.1 1 0 0 1 1 1 1 NPR1 interacting DUF2076 PF09849.9 CDJ66702.1 - 0.0045 17.1 15.4 0.005 16.9 15.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Activator_LAG-3 PF11498.8 CDJ66702.1 - 0.0062 15.6 25.9 0.0079 15.2 25.9 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 M_domain PF12938.7 CDJ66702.1 - 0.023 14.5 29.4 0.16 11.8 9.4 2.1 2 0 0 2 2 2 0 M domain of GW182 Peroxin-13_N PF04088.13 CDJ66702.1 - 0.12 12.7 0.8 9.3 6.5 0.2 2.0 2 0 0 2 2 2 0 Peroxin 13, N-terminal region GET2 PF08690.10 CDJ66702.1 - 0.23 11.1 9.1 0.29 10.8 9.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Neur_chan_memb PF02932.16 CDJ66702.1 - 0.27 11.2 2.7 0.33 11.0 2.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 CDJ66702.1 - 0.5 9.2 18.6 0.16 10.9 8.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ66702.1 - 0.57 8.9 2.6 0.71 8.6 2.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CDJ66702.1 - 1.5 8.1 5.0 1.9 7.8 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BatA PF07584.11 CDJ66702.1 - 6.8 7.1 7.7 0.43 11.0 1.1 2.0 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal GTA_holin_3TM PF11351.8 CDJ66702.1 - 7.3 7.2 9.2 30 5.2 0.1 2.2 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release TERB2 PF15101.6 CDJ66702.1 - 9.5 6.2 10.0 7.8 6.5 4.1 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF2722 PF10846.8 CDJ66703.1 - 0.0083 15.1 1.7 0.0097 14.9 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ66703.1 - 0.026 14.5 3.5 0.029 14.4 3.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peroxin-13_N PF04088.13 CDJ66703.1 - 0.17 12.1 0.1 0.25 11.6 0.1 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region BRCA2 PF00634.18 CDJ66704.1 - 8.6e-06 25.3 0.1 0.0099 15.5 0.0 2.3 2 0 0 2 2 2 2 BRCA2 repeat BRCA-2_OB1 PF09103.10 CDJ66704.1 - 0.015 15.3 0.0 0.12 12.4 0.0 2.6 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 GramPos_pilinD1 PF16555.5 CDJ66704.1 - 0.028 14.6 0.2 0.028 14.6 0.2 3.2 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain Nucleoporin2 PF04096.14 CDJ66704.1 - 5.7 7.0 5.2 0.51 10.4 0.3 1.7 2 0 0 2 2 2 0 Nucleoporin autopeptidase NPR3 PF03666.13 CDJ66706.1 - 0.019 13.8 3.8 0.026 13.3 3.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PNISR PF15996.5 CDJ66706.1 - 0.092 13.0 13.4 0.16 12.2 13.4 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF966 PF06136.13 CDJ66706.1 - 0.15 11.7 13.9 0.17 11.5 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Apt1 PF10351.9 CDJ66706.1 - 0.29 9.9 8.8 0.36 9.6 8.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 CDJ66706.1 - 0.91 7.6 9.2 1.1 7.4 9.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF368 PF04018.13 CDJ66706.1 - 1.4 8.4 7.1 0.076 12.6 2.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF368) DUF572 PF04502.13 CDJ66706.1 - 1.5 8.4 11.2 2 7.9 11.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.16 CDJ66706.1 - 1.5 8.8 7.3 2 8.4 7.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WDCP PF15390.6 CDJ66706.1 - 3.4 5.9 9.6 4.1 5.7 9.6 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF4366 PF14283.6 CDJ66706.1 - 3.5 7.7 15.9 4.2 7.4 1.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Ndc1_Nup PF09531.10 CDJ66706.1 - 5.6 5.5 13.7 6.9 5.2 13.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Smg8_Smg9 PF10220.9 CDJ66706.1 - 6.6 4.9 10.6 9.5 4.4 10.6 1.3 1 0 0 1 1 1 0 Smg8_Smg9 Utp14 PF04615.13 CDJ66706.1 - 7.2 5.1 18.9 9.1 4.7 18.9 1.0 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 CDJ66706.1 - 9.1 3.2 16.1 9.7 3.2 16.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3446 PF11928.8 CDJ66707.1 - 0.013 15.8 7.6 0.02 15.2 7.6 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ66707.1 - 0.14 11.7 11.4 0.2 11.2 11.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ66708.1 - 5.7e-06 25.6 0.4 5.7e-06 25.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ66708.1 - 0.017 15.1 15.9 0.017 15.1 15.9 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CDJ66708.1 - 0.063 12.0 0.3 0.054 12.2 0.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4736 PF15883.5 CDJ66708.1 - 0.16 11.7 7.2 0.24 11.1 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) Suf PF05843.14 CDJ66708.1 - 0.17 11.8 4.8 0.21 11.5 4.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ66708.1 - 0.24 11.0 18.1 0.32 10.6 18.1 1.1 1 0 0 1 1 1 0 Spt20 family DivIC PF04977.15 CDJ66708.1 - 0.35 10.7 11.8 0.56 10.0 11.8 1.2 1 0 0 1 1 1 0 Septum formation initiator UL73_N PF12522.8 CDJ66708.1 - 0.57 10.0 6.1 1.4 8.8 6.1 1.7 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal DUF4834 PF16118.5 CDJ66708.1 - 1.1 10.2 5.9 1.7 9.6 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Coilin_N PF15862.5 CDJ66708.1 - 1.7 8.4 8.8 2.5 7.9 8.8 1.2 1 0 0 1 1 1 0 Coilin N-terminus CDC45 PF02724.14 CDJ66708.1 - 1.8 6.7 6.2 2.3 6.4 6.2 1.0 1 0 0 1 1 1 0 CDC45-like protein eIF-3_zeta PF05091.12 CDJ66708.1 - 2.3 7.1 7.6 2.8 6.8 7.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FlaG PF03646.15 CDJ66708.1 - 2.6 8.2 10.4 5 7.4 10.4 1.4 1 0 0 1 1 1 0 FlaG protein DUF5327 PF17261.2 CDJ66708.1 - 6.4 7.6 16.2 3.2 8.5 9.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5327) AIF_C PF14721.6 CDJ66708.1 - 7.7 6.9 6.8 12 6.2 6.8 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF5521 PF17659.1 CDJ66708.1 - 8.8 4.0 7.0 12 3.6 7.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Baculo_PP31 PF05311.11 CDJ66708.1 - 9.4 5.6 7.8 12 5.2 7.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) UPF0242 PF06785.11 CDJ66710.1 - 0.088 12.9 13.1 0.17 11.9 13.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4482 PF14818.6 CDJ66710.1 - 0.35 11.7 8.3 0.41 11.5 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) APG6_N PF17675.1 CDJ66710.1 - 1.3 9.5 13.9 1.6 9.3 13.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3552 PF12072.8 CDJ66710.1 - 2.7 7.4 18.5 2 7.8 16.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) OmpH PF03938.14 CDJ66710.1 - 4.5 7.6 11.0 5.2 7.4 11.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cnn_1N PF07989.11 CDJ66710.1 - 5.2 7.3 13.7 0.88 9.8 4.5 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Suf PF05843.14 CDJ66711.1 - 3 7.8 7.8 4.3 7.2 7.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ66711.1 - 3.1 7.4 16.3 4.4 6.9 16.3 1.2 1 0 0 1 1 1 0 Spt20 family PBP_like PF12727.7 CDJ66711.1 - 5.7 6.0 9.0 0.15 11.2 1.6 2.1 2 0 0 2 2 2 0 PBP superfamily domain DUF4834 PF16118.5 CDJ66711.1 - 6.6 7.8 6.1 11 7.1 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Paf67 PF10255.9 CDJ66712.1 - 2.6e-95 319.8 0.0 3.3e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 CDJ66712.1 - 0.0013 18.7 0.0 0.0042 17.1 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF568 PF04526.13 CDJ66712.1 - 0.12 13.1 0.0 3.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF568) RT_RNaseH_2 PF17919.1 CDJ66714.1 - 7.9e-26 90.0 0.0 1.4e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ66714.1 - 1.7e-16 60.4 0.0 2.9e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ66714.1 - 1.5e-15 57.4 0.0 2.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Spt20 PF12090.8 CDJ66717.1 - 0.024 14.3 13.5 0.026 14.1 13.5 1.2 1 0 0 1 1 1 0 Spt20 family DUF3824 PF12868.7 CDJ66717.1 - 0.024 15.3 5.0 0.024 15.3 5.0 2.3 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) TFIIA PF03153.13 CDJ66717.1 - 0.031 14.3 14.9 0.035 14.1 14.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.8 CDJ66717.1 - 0.11 11.6 18.8 0.14 11.3 18.8 1.1 1 0 0 1 1 1 0 SprA-related family Baculo_PP31 PF05311.11 CDJ66717.1 - 0.66 9.4 5.7 0.77 9.2 5.7 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Raftlin PF15250.6 CDJ66717.1 - 0.87 8.3 6.4 1 8.0 6.4 1.0 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 CDJ66717.1 - 1.2 7.9 6.1 1.5 7.5 6.1 1.2 1 0 0 1 1 1 0 Presenilin DUF3682 PF12446.8 CDJ66717.1 - 1.4 9.4 29.5 3 8.3 29.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) DivIC PF04977.15 CDJ66717.1 - 4.4 7.1 12.4 6.9 6.5 12.4 1.2 1 0 0 1 1 1 0 Septum formation initiator Med3 PF11593.8 CDJ66717.1 - 7.9 5.5 34.4 5.4 6.1 33.3 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Fis1_TPR_C PF14853.6 CDJ66718.1 - 4.2e-08 33.1 0.1 4.2e-07 29.9 0.1 2.3 1 1 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CDJ66718.1 - 6.1e-06 25.8 0.0 9.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 CDJ66718.1 - 0.036 14.2 0.1 0.14 12.4 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2076 PF09849.9 CDJ66719.1 - 1.3 9.0 22.5 0.1 12.6 10.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Spt20 PF12090.8 CDJ66719.1 - 6.6 6.3 22.8 9 5.8 15.4 2.2 2 0 0 2 2 2 0 Spt20 family DNA_pol_E_B PF04042.16 CDJ66721.1 - 1.4e-14 54.0 0.6 1.4e-14 54.0 0.6 2.1 2 1 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B SUIM_assoc PF16619.5 CDJ66721.1 - 0.013 15.5 28.6 0.21 11.7 1.6 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ66721.1 - 0.1 12.2 25.2 0.26 10.8 5.1 2.4 2 0 0 2 2 2 0 Spt20 family Suf PF05843.14 CDJ66721.1 - 0.65 9.9 6.9 3.1 7.7 0.3 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) C2 PF00168.30 CDJ66722.1 - 2.1e-35 121.1 0.1 5.1e-09 36.3 0.0 6.9 7 0 0 7 7 7 6 C2 domain Ferlin_C PF16165.5 CDJ66722.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Ferlin C-terminus FerI PF08151.12 CDJ66722.1 - 0.08 13.0 0.0 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 FerI (NUC094) domain zf-RING_2 PF13639.6 CDJ66723.1 - 1.2e-09 38.3 12.7 2.1e-09 37.5 12.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDJ66723.1 - 1e-07 31.6 7.3 2.4e-07 30.4 7.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDJ66723.1 - 1.5e-06 28.0 8.2 2.5e-06 27.3 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ66723.1 - 2.7e-05 23.9 8.6 4.9e-05 23.1 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CDJ66723.1 - 0.0001 21.8 8.5 0.00019 21.0 8.5 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 CDJ66723.1 - 0.00016 21.9 10.2 0.00055 20.2 10.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDJ66723.1 - 0.00082 19.3 5.9 0.0016 18.5 5.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CDJ66723.1 - 0.0023 17.9 4.1 0.0052 16.8 4.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Caa3_CtaG PF09678.10 CDJ66723.1 - 0.016 14.6 0.3 0.025 14.1 0.3 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) zf-RING_5 PF14634.6 CDJ66723.1 - 0.1 12.6 10.1 0.23 11.4 10.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.7 CDJ66723.1 - 0.13 12.4 8.2 0.32 11.1 8.2 1.7 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 CDJ66723.1 - 0.17 11.7 5.0 0.36 10.7 5.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 CDJ66723.1 - 0.43 10.5 10.1 0.82 9.6 10.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 CDJ66723.1 - 0.52 10.7 6.5 1.2 9.4 6.5 1.7 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 CDJ66723.1 - 1.8 8.8 10.0 6.4 7.0 10.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 CDJ66723.1 - 1.9 8.7 7.8 3.6 7.8 7.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pox_A_type_inc PF04508.12 CDJ66724.1 - 0.00053 19.7 4.2 0.36 10.7 0.6 3.4 2 1 1 3 3 3 2 Viral A-type inclusion protein repeat Phosphodiest PF01663.22 CDJ66725.1 - 0.00015 21.5 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1525 PF07511.11 CDJ66726.1 - 6.5 6.9 7.1 0.64 10.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) cNMP_binding PF00027.29 CDJ66728.1 - 2.5e-25 88.4 0.1 1.9e-15 56.7 0.0 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 CDJ66729.1 - 1.7e-57 191.4 0.2 4e-19 68.5 0.0 4.6 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain EF-hand_1 PF00036.32 CDJ66729.1 - 1e-06 27.9 0.4 0.058 13.0 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CDJ66729.1 - 6.8e-06 25.6 0.7 0.43 10.6 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CDJ66729.1 - 6.3e-05 22.8 1.3 0.08 12.8 0.1 3.9 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.6 CDJ66729.1 - 0.00014 22.3 6.5 0.84 10.1 0.0 5.0 5 1 1 6 6 6 3 EF-hand domain pair EF-hand_5 PF13202.6 CDJ66729.1 - 0.027 14.0 0.0 13 5.5 0.0 2.9 2 0 0 2 2 2 0 EF hand EF-hand_11 PF08976.11 CDJ66729.1 - 0.07 14.0 0.0 0.39 11.6 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain WD40_alt PF14077.6 CDJ66729.1 - 0.5 10.3 14.1 5.2 7.0 2.2 4.0 3 0 0 3 3 3 0 Alternative WD40 repeat motif RRM_1 PF00076.22 CDJ66731.1 - 1e-17 63.7 0.0 8.7e-12 44.7 0.0 4.1 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ66731.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ66731.1 - 0.013 15.4 0.0 0.056 13.3 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif TrmB PF01978.19 CDJ66731.1 - 0.045 13.6 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB PRP21_like_P PF12230.8 CDJ66732.1 - 2e-42 145.5 2.9 2e-42 145.5 2.9 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CDJ66732.1 - 6.7e-36 122.1 2.7 1.4e-16 60.3 0.2 3.4 3 0 0 3 3 3 2 Surp module DUF1682 PF07946.14 CDJ66732.1 - 0.0035 16.6 1.7 0.0035 16.6 1.7 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1682) TNT PF14021.6 CDJ66732.1 - 0.12 12.9 0.1 0.35 11.5 0.1 1.7 1 0 0 1 1 1 0 Tuberculosis necrotizing toxin DUF572 PF04502.13 CDJ66732.1 - 8.3 5.9 11.3 3 7.4 5.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Peptidase_S9 PF00326.21 CDJ66733.1 - 1.7e-26 93.1 0.0 1.7e-21 76.7 0.0 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ66733.1 - 1.8e-06 27.8 0.3 5.6e-06 26.2 0.3 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CDJ66733.1 - 0.00035 19.6 0.0 0.00035 19.6 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S28 PF05577.12 CDJ66733.1 - 0.0086 14.9 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Esterase_phd PF10503.9 CDJ66733.1 - 0.023 14.2 0.1 0.068 12.6 0.0 1.8 2 0 0 2 2 2 0 Esterase PHB depolymerase TFIIA PF03153.13 CDJ66733.1 - 0.31 11.0 26.9 0.5 10.3 26.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LCD1 PF09798.9 CDJ66733.1 - 3.1 6.2 8.2 4.3 5.7 8.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein ASH PF15780.5 CDJ66734.1 - 0.0016 18.6 0.6 1.4 9.2 0.0 5.1 6 0 0 6 6 6 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CDJ66734.1 - 0.0023 18.1 0.6 1.4 9.1 0.0 4.1 4 0 0 4 4 4 1 Flagellar-associated PapD-like Gemin6 PF06372.12 CDJ66734.1 - 0.017 14.7 0.2 0.037 13.6 0.2 1.5 1 0 0 1 1 1 0 Gemin6 protein HipN PF18253.1 CDJ66735.1 - 3.8e-15 55.3 0.3 8.9e-15 54.1 0.1 1.7 2 0 0 2 2 2 1 Hsp70-interacting protein N N-terminal domain TPR_1 PF00515.28 CDJ66735.1 - 1.2e-10 40.7 4.6 6.6e-09 35.2 0.4 3.0 3 1 0 3 3 3 2 Tetratricopeptide repeat STI1 PF17830.1 CDJ66735.1 - 1.8e-10 40.6 2.6 5.1e-10 39.1 2.6 1.8 1 0 0 1 1 1 1 STI1 domain TPR_16 PF13432.6 CDJ66735.1 - 2.6e-09 37.6 10.6 3e-06 27.8 4.1 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ66735.1 - 1.3e-08 34.3 9.8 4.1e-07 29.6 0.6 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ66735.1 - 4.1e-07 29.6 2.4 4.6e-05 23.0 0.4 2.5 1 1 1 2 2 2 2 TPR repeat TPR_9 PF13371.6 CDJ66735.1 - 6e-05 23.1 3.3 9.6e-05 22.5 1.6 2.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ66735.1 - 6.8e-05 23.4 4.5 0.00035 21.2 0.6 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ66735.1 - 0.00053 20.4 1.5 0.00053 20.4 1.5 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ66735.1 - 0.00098 19.2 8.7 0.0013 18.8 0.1 3.4 3 1 1 4 4 3 1 Tetratricopeptide repeat DUF1641 PF07849.11 CDJ66735.1 - 0.012 15.5 0.1 0.041 13.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_12 PF13424.6 CDJ66735.1 - 0.012 15.9 0.5 0.012 15.9 0.5 2.8 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ66735.1 - 0.027 14.8 0.5 1.1 9.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ66735.1 - 0.29 11.1 1.7 0.78 9.7 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PTPRCAP PF15713.5 CDJ66735.1 - 0.45 10.8 12.2 0.23 11.8 4.5 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated TMA7 PF09072.10 CDJ66735.1 - 4 8.4 14.8 1.2 10.0 3.2 3.2 3 0 0 3 3 2 0 Translation machinery associated TMA7 BSD PF03909.17 CDJ66736.1 - 4.4e-06 26.6 0.2 0.036 14.1 0.1 3.1 2 0 0 2 2 2 2 BSD domain FTHFS PF01268.19 CDJ66736.1 - 0.033 12.4 0.9 0.049 11.8 0.9 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase PLDc PF00614.22 CDJ66737.1 - 1.9e-08 34.1 0.0 0.0063 16.7 0.0 3.5 3 1 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CDJ66737.1 - 2.8e-07 30.5 0.0 0.0047 16.8 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain USP7_C2 PF14533.6 CDJ66738.1 - 0.054 13.2 0.8 0.12 12.1 0.8 1.5 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal cwf21 PF08312.12 CDJ66739.1 - 6.1e-08 32.7 8.3 6.1e-08 32.7 8.3 3.0 3 0 0 3 3 3 1 cwf21 domain PI3K_1B_p101 PF10486.9 CDJ66739.1 - 0.0026 15.6 28.6 0.0039 15.1 28.6 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit LCD1 PF09798.9 CDJ66739.1 - 6.7 5.1 14.9 8.9 4.7 14.9 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein CKS PF01111.19 CDJ66741.1 - 1.3e-06 28.6 0.0 3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DnaJ_C PF01556.18 CDJ66742.1 - 1.4e-27 96.6 0.0 1.3e-26 93.5 0.0 2.0 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CDJ66742.1 - 2.4e-07 31.0 15.8 5.1e-07 30.0 15.8 1.6 1 0 0 1 1 1 1 DnaJ central domain DZR PF12773.7 CDJ66742.1 - 0.14 12.2 11.5 0.24 11.5 10.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon PHD_4 PF16866.5 CDJ66742.1 - 0.14 12.3 3.1 0.11 12.6 1.4 1.7 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 CDJ66742.1 - 1.9 8.4 7.0 2 8.4 1.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TackOD1 PF18551.1 CDJ66742.1 - 2.3 7.8 8.9 4.2 7.0 1.3 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 M20_dimer PF07687.14 CDJ66743.1 - 5.7e-08 32.6 0.0 9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 CDJ66743.1 - 8e-05 22.4 0.0 0.00017 21.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M20 PF01546.28 CDJ66744.1 - 1.5e-09 37.8 0.0 1.2e-06 28.4 0.0 3.4 3 0 0 3 3 3 1 Peptidase family M20/M25/M40 WD40 PF00400.32 CDJ66744.1 - 4.8e-09 36.7 13.9 0.14 13.1 0.0 6.5 5 1 0 5 5 5 3 WD domain, G-beta repeat FlxA PF14282.6 CDJ66744.1 - 0.063 13.3 0.4 0.15 12.1 0.4 1.6 1 0 0 1 1 1 0 FlxA-like protein DUF4890 PF16231.5 CDJ66747.1 - 0.33 11.5 3.8 1 9.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) DUF3381 PF11861.8 CDJ66748.1 - 0.036 13.9 4.7 0.073 12.9 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) MCC-bdg_PDZ PF10506.9 CDJ66748.1 - 0.039 14.0 1.5 3.1 7.9 0.1 3.1 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF5446 PF17522.2 CDJ66748.1 - 0.14 12.4 0.8 0.41 10.8 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5446) V-SNARE_C PF12352.8 CDJ66748.1 - 1.2 9.5 8.6 7.2 7.0 0.0 3.9 4 1 1 5 5 5 0 Snare region anchored in the vesicle membrane C-terminus ABC_tran_CTD PF16326.5 CDJ66748.1 - 4 7.7 9.2 2.1 8.7 0.7 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain CLZ PF16526.5 CDJ66748.1 - 9.3 6.7 11.7 0.77 10.2 3.4 3.1 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels A_deaminase PF00962.22 CDJ66749.1 - 1.7e-62 211.7 0.0 3e-62 210.9 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2397 PF09660.10 CDJ66750.1 - 0.035 13.0 6.6 0.04 12.8 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF2597 PF10772.9 CDJ66750.1 - 0.33 11.0 1.0 1.8 8.6 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2597) FUSC PF04632.12 CDJ66750.1 - 1 7.8 9.9 1.2 7.6 9.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3138 PF11336.8 CDJ66750.1 - 2 7.0 7.5 2.1 6.8 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2722 PF10846.8 CDJ66753.1 - 0.0026 16.8 25.3 0.0028 16.7 25.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DDHD PF02862.17 CDJ66753.1 - 0.034 14.3 5.8 0.031 14.4 5.8 1.1 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.8 CDJ66753.1 - 0.041 12.7 6.4 0.039 12.8 6.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PIG-S PF10510.9 CDJ66753.1 - 0.072 11.9 8.8 0.073 11.9 8.8 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF702 PF05142.12 CDJ66753.1 - 0.086 13.3 8.5 0.091 13.2 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) EPL1 PF10513.9 CDJ66753.1 - 0.14 12.5 10.1 0.14 12.5 10.1 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Spt20 PF12090.8 CDJ66753.1 - 0.16 11.6 41.2 0.18 11.4 41.2 1.2 1 0 0 1 1 1 0 Spt20 family NST1 PF13945.6 CDJ66753.1 - 0.17 12.0 17.2 0.19 11.8 17.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator SpoIIP PF07454.11 CDJ66753.1 - 0.31 10.5 11.8 0.3 10.5 11.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4175 PF13779.6 CDJ66753.1 - 0.33 8.8 28.7 0.33 8.8 28.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF5385 PF17359.2 CDJ66753.1 - 0.38 10.3 10.1 0.43 10.1 10.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Med15 PF09606.10 CDJ66753.1 - 0.44 9.2 30.4 0.51 9.0 30.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4770 PF15994.5 CDJ66753.1 - 0.48 10.6 12.4 0.49 10.6 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) TFIIA PF03153.13 CDJ66753.1 - 0.53 10.2 36.1 0.59 10.1 36.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Eapp_C PF10238.9 CDJ66753.1 - 0.55 10.3 12.3 0.6 10.2 12.3 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF3292 PF11696.8 CDJ66753.1 - 0.72 8.2 6.7 0.76 8.1 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Plasmodium_Vir PF05795.11 CDJ66753.1 - 0.76 9.1 4.8 0.7 9.3 4.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM91_C PF14648.6 CDJ66753.1 - 0.89 8.3 4.6 0.8 8.5 4.6 1.1 1 0 0 1 1 1 0 FAM91 C-terminus OATP PF03137.20 CDJ66753.1 - 0.97 7.6 5.2 0.93 7.7 5.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family BAF1_ABF1 PF04684.13 CDJ66753.1 - 0.99 8.4 11.9 1.1 8.2 11.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MMR1 PF08505.10 CDJ66753.1 - 1.1 9.5 14.4 1.1 9.5 14.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GREB1 PF15782.5 CDJ66753.1 - 1.1 6.2 12.2 1.2 6.2 12.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CobT PF06213.12 CDJ66753.1 - 1.2 8.5 21.1 1.3 8.3 21.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MDM10 PF12519.8 CDJ66753.1 - 1.2 7.9 7.7 1.2 7.9 7.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 BRF1 PF07741.13 CDJ66753.1 - 1.3 9.4 12.3 1.6 9.1 12.3 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF2076 PF09849.9 CDJ66753.1 - 1.5 8.8 29.5 1.9 8.5 29.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MPM1 PF17234.2 CDJ66753.1 - 1.7 8.8 15.5 2.2 8.5 15.5 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 RED_N PF07808.13 CDJ66753.1 - 2.1 7.9 13.7 2.1 7.8 13.7 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Presenilin PF01080.17 CDJ66753.1 - 2.2 7.0 15.5 2.3 6.9 15.5 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ66753.1 - 2.3 8.0 11.0 2.3 7.9 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 CDJ66753.1 - 2.4 7.8 8.0 2.7 7.7 8.0 1.1 1 0 0 1 1 1 0 FAM176 family ABC2_membrane_2 PF12679.7 CDJ66753.1 - 2.6 7.2 7.0 3.2 7.0 7.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein TERB2 PF15101.6 CDJ66753.1 - 2.8 7.9 19.2 2.9 7.9 19.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Suf PF05843.14 CDJ66753.1 - 3.4 7.6 17.2 3.3 7.6 17.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 CDJ66753.1 - 3.6 6.1 14.8 3.8 6.1 14.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CPSF100_C PF13299.6 CDJ66753.1 - 3.7 7.7 11.4 4.2 7.5 11.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF775 PF05603.12 CDJ66753.1 - 3.7 7.0 14.4 5 6.6 14.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) PAT1 PF09770.9 CDJ66753.1 - 4.1 5.5 23.4 4.1 5.5 23.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ66753.1 - 4.5 5.5 10.1 4.5 5.5 10.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Gti1_Pac2 PF09729.9 CDJ66753.1 - 4.6 7.3 10.5 5 7.2 10.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 CDJ66753.1 - 5 6.0 12.1 5 6.0 12.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 CDJ66753.1 - 5.3 5.7 10.7 5.3 5.7 10.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Band_3_cyto PF07565.13 CDJ66753.1 - 6 6.6 11.6 6.1 6.6 11.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Sec62 PF03839.16 CDJ66753.1 - 6.2 6.3 8.1 6.5 6.2 8.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 PPL5 PF18168.1 CDJ66753.1 - 6.3 6.0 9.1 6.7 5.9 9.1 1.1 1 0 0 1 1 1 0 Prim-pol family 5 AIF_C PF14721.6 CDJ66753.1 - 6.5 7.1 11.7 8.5 6.7 11.7 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3371 PF11851.8 CDJ66753.1 - 6.7 7.8 16.2 9.1 7.4 16.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) MDM31_MDM32 PF08118.11 CDJ66753.1 - 7.3 5.1 8.5 7.3 5.1 8.5 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins CNDH2_M PF16869.5 CDJ66753.1 - 7.4 7.3 11.2 8.4 7.1 11.2 1.1 1 0 0 1 1 1 0 PF16858 Ctr PF04145.15 CDJ66753.1 - 7.4 7.2 6.9 8.3 7.0 6.9 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF4746 PF15928.5 CDJ66753.1 - 8.2 5.7 9.2 8.3 5.7 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4638 PF15472.6 CDJ66753.1 - 8.3 6.1 10.5 8.6 6.0 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Peptidase_S49_N PF08496.10 CDJ66753.1 - 9.3 6.3 11.6 11 6.0 11.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM60A PF15396.6 CDJ66753.1 - 9.3 6.2 9.0 9.9 6.1 9.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A XTBD PF11952.8 CDJ66754.1 - 3.2e-07 30.0 0.9 5.8e-07 29.2 0.9 1.4 1 0 0 1 1 1 1 XRN-Two Binding Domain, XTBD ASF1_hist_chap PF04729.13 CDJ66756.1 - 3.9e-08 33.4 0.1 5.4e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone MRAP PF15183.6 CDJ66757.1 - 0.0094 15.9 0.1 3.2 7.8 0.0 2.2 2 0 0 2 2 2 1 Melanocortin-2 receptor accessory protein family BatD PF13584.6 CDJ66757.1 - 0.0098 14.8 1.4 0.0098 14.8 1.4 1.7 2 0 0 2 2 2 1 Oxygen tolerance BPD_transp_2 PF02653.16 CDJ66757.1 - 0.013 14.7 1.6 0.021 14.0 1.6 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component TFIIA PF03153.13 CDJ66757.1 - 0.016 15.2 1.5 0.018 15.0 1.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YajC PF02699.15 CDJ66757.1 - 0.037 13.9 2.5 0.037 13.9 2.5 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit SUIM_assoc PF16619.5 CDJ66757.1 - 0.037 14.1 1.4 0.037 14.1 1.4 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 EphA2_TM PF14575.6 CDJ66757.1 - 0.068 14.1 0.0 0.99 10.3 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FHIPEP PF00771.20 CDJ66757.1 - 0.23 9.9 1.2 0.27 9.6 1.2 1.1 1 0 0 1 1 1 0 FHIPEP family Baculo_11_kDa PF06143.11 CDJ66757.1 - 0.24 11.0 0.9 3.8 7.2 0.1 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family CcmD PF04995.14 CDJ66757.1 - 1.9 8.6 19.6 0.46 10.6 8.5 2.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Ribosomal_60s PF00428.19 CDJ66757.1 - 2.5 8.8 15.4 4.4 8.0 15.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Conotoxin PF02950.17 CDJ66757.1 - 2.6 9.1 6.3 4.7 8.3 0.4 2.7 3 0 0 3 3 3 0 Conotoxin Adeno_PV PF03910.13 CDJ66757.1 - 3.4 6.3 6.4 4.7 5.8 6.4 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF3619 PF12279.8 CDJ66757.1 - 6.4 7.1 17.1 4.4 7.6 10.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) TMEM51 PF15345.6 CDJ66757.1 - 8.2 6.2 7.0 0.72 9.7 2.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 Peptidase_M41 PF01434.18 CDJ66758.1 - 1.6e-38 132.5 4.9 4.9e-36 124.4 4.9 2.1 1 1 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 CDJ66758.1 - 5.5e-06 26.1 0.8 1.1e-05 25.2 0.2 1.8 2 0 0 2 2 2 1 AAA+ lid domain DUF3446 PF11928.8 CDJ66758.1 - 0.066 13.5 13.4 0.19 12.0 13.4 1.8 1 0 0 1 1 1 0 Early growth response N-terminal domain Peptidase_M50B PF13398.6 CDJ66758.1 - 0.16 11.6 0.2 0.27 10.8 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Neuregulin PF02158.15 CDJ66758.1 - 0.22 10.8 9.9 0.31 10.3 9.9 1.3 1 0 0 1 1 1 0 Neuregulin intracellular region DUF515 PF04415.12 CDJ66758.1 - 0.44 8.9 9.5 0.61 8.4 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Corona_nucleoca PF00937.18 CDJ66758.1 - 0.49 9.4 3.6 0.65 9.0 3.6 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DEAD PF00270.29 CDJ66759.1 - 1e-43 149.2 0.0 4.1e-43 147.2 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ66759.1 - 9.4e-31 106.4 0.0 4.5e-30 104.2 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ66759.1 - 3.8e-06 27.0 0.0 1.4e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CDJ66759.1 - 0.013 14.8 0.2 0.024 14.0 0.2 1.5 1 1 0 1 1 1 0 SecA DEAD-like domain Aldolase PF01081.19 CDJ66759.1 - 0.098 12.1 0.0 1 8.7 0.0 2.4 3 0 0 3 3 3 0 KDPG and KHG aldolase zf-CCHC PF00098.23 CDJ66759.1 - 4.1 7.7 8.6 0.35 11.0 3.6 1.9 2 0 0 2 2 2 0 Zinc knuckle eIF-3_zeta PF05091.12 CDJ66762.1 - 0.81 8.6 8.9 1.6 7.6 8.9 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Galactosyl_T PF01762.21 CDJ66764.1 - 3.5e-44 151.0 0.0 4.3e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 CDJ66764.1 - 2.7e-05 23.8 0.0 3.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CDJ66765.1 - 1e-29 103.8 0.0 4.3e-27 95.2 0.0 2.0 2 0 0 2 2 2 2 Galactosyltransferase PMT_4TMC PF16192.5 CDJ66765.1 - 0.053 13.1 0.4 0.13 11.9 0.3 1.7 1 1 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase MMR_HSR1 PF01926.23 CDJ66766.1 - 1.5e-09 37.9 0.0 3.4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ66766.1 - 0.0041 17.0 0.1 0.051 13.5 0.1 2.3 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CDJ66766.1 - 0.0042 16.6 0.0 0.95 9.0 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Spore_IV_A PF09547.10 CDJ66766.1 - 0.0069 15.4 0.0 0.0098 14.9 0.0 1.1 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) Dynamin_N PF00350.23 CDJ66766.1 - 0.0074 16.4 4.5 0.04 14.0 0.2 2.5 3 0 0 3 3 3 1 Dynamin family RskA PF10099.9 CDJ66766.1 - 0.014 15.7 6.1 0.021 15.1 6.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA G-alpha PF00503.20 CDJ66766.1 - 0.034 13.3 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 CDJ66766.1 - 0.072 12.8 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain K_channel_TID PF07941.11 CDJ66766.1 - 0.097 13.1 14.7 0.16 12.5 14.7 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain SUIM_assoc PF16619.5 CDJ66766.1 - 0.32 11.1 7.6 0.61 10.2 7.6 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 CDJ66766.1 - 0.88 8.7 8.1 1.3 8.1 8.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HA2 PF04408.23 CDJ66767.1 - 1.7e-23 82.9 0.6 5.8e-23 81.2 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDJ66767.1 - 1.6e-11 44.5 0.0 3.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDJ66767.1 - 6.4e-11 42.5 0.1 2.3e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Med15 PF09606.10 CDJ66767.1 - 0.0091 14.7 6.0 0.015 14.0 6.0 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SSP160 PF06933.11 CDJ66767.1 - 0.056 11.6 16.3 0.074 11.2 16.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SPX PF03105.19 CDJ66767.1 - 0.17 11.8 7.3 0.085 12.8 3.9 1.8 2 0 0 2 2 2 0 SPX domain dsDNA_bind PF01984.20 CDJ66767.1 - 0.18 12.1 5.7 0.4 11.0 5.7 1.5 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Spt20 PF12090.8 CDJ66767.1 - 0.38 10.3 6.5 0.78 9.3 6.5 1.5 1 0 0 1 1 1 0 Spt20 family OATP PF03137.20 CDJ66767.1 - 1.1 7.4 6.1 0.15 10.3 0.4 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TPR_8 PF13181.6 CDJ66768.1 - 5.8e-10 38.6 0.9 0.0054 16.8 0.2 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ66768.1 - 7.5e-07 29.6 9.4 1.4e-05 25.5 0.3 5.8 5 1 1 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ66768.1 - 5.7e-06 26.0 9.6 0.00074 19.4 0.3 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ66768.1 - 9.2e-06 25.3 2.2 0.0058 16.4 0.3 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ66768.1 - 1.8e-05 25.2 33.8 0.036 14.9 1.5 7.4 5 3 2 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ66768.1 - 0.00011 21.8 4.1 1.1 9.0 0.2 4.0 4 0 0 4 4 4 2 TPR repeat TPR_9 PF13371.6 CDJ66768.1 - 0.00014 21.9 18.6 0.019 15.1 0.1 4.5 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ66768.1 - 0.00032 20.9 0.1 5.5 7.6 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ66768.1 - 0.014 15.7 0.1 0.014 15.7 0.1 4.3 3 1 2 5 5 5 0 Tetratricopeptide repeat RTP PF02334.16 CDJ66768.1 - 0.044 14.4 0.3 0.18 12.4 0.2 1.9 2 0 0 2 2 2 0 Replication terminator protein TPR_6 PF13174.6 CDJ66768.1 - 0.09 13.5 0.3 0.09 13.5 0.3 4.0 5 0 0 5 5 1 0 Tetratricopeptide repeat Lin-8 PF03353.15 CDJ66768.1 - 2.5 7.6 12.0 3.7 7.0 0.4 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ66768.1 - 2.7 7.5 25.8 1.1 8.9 15.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ66768.1 - 3.7 7.9 17.4 0.11 12.8 10.1 2.2 3 0 0 3 3 2 0 Early growth response N-terminal domain Ndc1_Nup PF09531.10 CDJ66768.1 - 5.6 5.5 10.6 0.8 8.3 3.5 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup TFIIF_alpha PF05793.12 CDJ66768.1 - 7.2 5.1 13.8 8.9 4.8 0.5 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IMUP PF15761.5 CDJ66768.1 - 7.6 7.3 23.9 0.87 10.3 9.0 2.9 3 0 0 3 3 3 0 Immortalisation up-regulated protein SUIM_assoc PF16619.5 CDJ66769.1 - 0.09 12.9 21.9 1.2 9.2 10.8 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SAGA-Tad1 PF12767.7 CDJ66769.1 - 0.71 9.6 3.0 0.91 9.2 2.1 1.7 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2722 PF10846.8 CDJ66769.1 - 0.76 8.7 9.1 0.31 9.9 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) NIF PF03031.18 CDJ66771.1 - 5.1e-13 49.1 0.0 4.7e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Spt20 PF12090.8 CDJ66771.1 - 2.2 7.8 66.3 0.66 9.5 5.6 3.2 3 0 0 3 3 3 0 Spt20 family SID-1_RNA_chan PF13965.6 CDJ66771.1 - 7 4.9 4.8 6.8 5.0 3.7 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 RskA PF10099.9 CDJ66772.1 - 0.39 11.0 50.2 26 5.0 16.1 4.9 1 1 2 3 3 3 0 Anti-sigma-K factor rskA DUF2339 PF10101.9 CDJ66773.1 - 0.042 12.4 4.2 0.054 12.1 4.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) SR-25 PF10500.9 CDJ66774.1 - 0.0096 15.5 7.7 0.0096 15.5 7.7 2.9 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.8 CDJ66775.1 - 0.21 10.5 24.6 0.31 10.0 24.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 eIF-3_zeta PF05091.12 CDJ66775.1 - 0.36 9.8 10.1 0.55 9.1 10.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ66775.1 - 1.6 8.7 33.5 2.1 8.3 33.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NEMP PF10225.9 CDJ66775.1 - 5.3 6.6 5.8 9.2 5.9 5.8 1.4 1 0 0 1 1 1 0 NEMP family GREB1 PF15782.5 CDJ66776.1 - 0.13 9.4 41.0 0.15 9.2 41.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CDJ66776.1 - 0.58 9.5 23.0 0.74 9.2 23.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDC45 PF02724.14 CDJ66776.1 - 2.3 6.4 32.2 2.8 6.1 32.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Membralin PF09746.9 CDJ66776.1 - 2.9 6.8 22.8 3.7 6.5 22.8 1.3 1 0 0 1 1 1 0 Tumour-associated protein ALMT PF11744.8 CDJ66776.1 - 3.8 6.3 31.8 5.1 5.8 31.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Draxin PF15550.6 CDJ66776.1 - 8.7 6.1 32.1 11 5.8 32.1 1.1 1 0 0 1 1 1 0 Draxin TFIIA PF03153.13 CDJ66777.1 - 0.0013 18.8 43.8 0.0013 18.8 43.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ66777.1 - 0.0034 17.0 30.8 0.0042 16.7 30.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 CDJ66777.1 - 0.02 15.4 16.1 0.023 15.2 16.1 1.3 1 0 0 1 1 1 0 AAA domain TCP PF03634.13 CDJ66777.1 - 0.025 15.1 21.3 0.033 14.8 21.3 1.4 1 0 0 1 1 1 0 TCP family transcription factor BAF1_ABF1 PF04684.13 CDJ66777.1 - 0.26 10.3 21.2 0.28 10.2 21.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor AUX_IAA PF02309.16 CDJ66777.1 - 0.51 10.1 14.1 0.5 10.2 14.1 1.2 1 0 0 1 1 1 0 AUX/IAA family PPP4R2 PF09184.11 CDJ66777.1 - 0.53 9.8 14.2 0.57 9.7 14.2 1.1 1 0 0 1 1 1 0 PPP4R2 LYRIC PF15686.5 CDJ66777.1 - 0.59 9.6 26.5 0.68 9.4 26.5 1.3 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family PAT1 PF09770.9 CDJ66777.1 - 0.62 8.3 35.0 0.62 8.3 35.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IMUP PF15761.5 CDJ66777.1 - 1.1 10.0 28.1 2.1 9.1 27.5 1.7 1 1 1 2 2 2 0 Immortalisation up-regulated protein SMYLE_N PF18615.1 CDJ66777.1 - 1.3 8.5 22.3 1.6 8.3 22.3 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain XRN_M PF17846.1 CDJ66777.1 - 1.5 7.7 17.3 1.5 7.7 17.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Velvet PF11754.8 CDJ66777.1 - 1.6 8.6 22.6 1.9 8.3 22.6 1.2 1 0 0 1 1 1 0 Velvet factor DUF2828 PF11443.8 CDJ66777.1 - 2.3 6.2 19.9 3 5.8 19.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Smg8_Smg9 PF10220.9 CDJ66777.1 - 3.3 5.9 24.0 3.3 5.9 24.0 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Hydin_ADK PF17213.3 CDJ66777.1 - 3.6 7.8 25.0 4.6 7.5 25.0 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CCSAP PF15748.5 CDJ66777.1 - 4.4 7.4 33.2 5.2 7.2 33.2 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ66777.1 - 4.8 6.9 30.9 5.8 6.7 30.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ66777.1 - 5.2 6.0 17.6 7.1 5.5 17.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.7 CDJ66777.1 - 5.7 4.9 25.6 6 4.9 25.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 CDJ66777.1 - 6.6 5.4 18.2 6.6 5.4 18.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 CDJ66777.1 - 7.7 6.5 20.1 8.5 6.4 20.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 CDJ66777.1 - 8.7 4.6 10.7 11 4.3 10.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PA26 PF04636.13 CDJ66777.1 - 9.9 5.0 20.8 11 4.8 20.8 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RRM_1 PF00076.22 CDJ66778.1 - 2.7e-11 43.1 0.1 1.5e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ66778.1 - 0.0016 18.3 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Phage_TAC_1 PF06222.11 CDJ66778.1 - 0.0081 15.9 0.2 0.058 13.2 0.2 2.1 1 1 0 1 1 1 1 Phage tail assembly chaperone Spt20 PF12090.8 CDJ66780.1 - 0.44 10.1 11.1 0.47 10.0 11.1 1.2 1 0 0 1 1 1 0 Spt20 family Dehydrin PF00257.19 CDJ66780.1 - 2.4 8.7 13.2 2.7 8.5 13.2 1.1 1 0 0 1 1 1 0 Dehydrin DUF726 PF05277.12 CDJ66780.1 - 6.3 5.6 11.6 5.9 5.7 11.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Presenilin PF01080.17 CDJ66782.1 - 1.5e-09 37.1 10.0 1.5e-09 37.1 10.0 2.3 3 0 0 3 3 3 1 Presenilin SNARE_assoc PF09335.11 CDJ66782.1 - 8.3e-08 32.7 1.0 4.5e-07 30.4 0.0 2.7 4 0 0 4 4 2 1 SNARE associated Golgi protein CDC45 PF02724.14 CDJ66782.1 - 0.0044 15.4 13.2 0.0044 15.4 13.2 2.2 3 0 0 3 3 3 1 CDC45-like protein Ctr PF04145.15 CDJ66782.1 - 0.021 15.4 0.2 0.021 15.4 0.2 4.2 3 1 0 3 3 2 0 Ctr copper transporter family Zip PF02535.22 CDJ66782.1 - 0.27 10.4 13.4 16 4.6 0.0 2.7 2 0 0 2 2 2 0 ZIP Zinc transporter DUF913 PF06025.12 CDJ66782.1 - 0.77 8.7 12.6 1.7 7.6 11.8 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) LMBR1 PF04791.16 CDJ66782.1 - 0.98 8.3 10.6 2.8 6.7 0.2 2.4 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF4149 PF13664.6 CDJ66782.1 - 3.2 8.1 11.3 11 6.5 4.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) RR_TM4-6 PF06459.12 CDJ66782.1 - 3.4 7.4 29.2 0.22 11.3 23.2 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 CDJ66782.1 - 3.8 6.2 22.0 0.16 10.8 16.2 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4179 PF13786.6 CDJ66782.1 - 4.2 7.9 8.3 12 6.4 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) DUF4667 PF15700.5 CDJ66783.1 - 0.022 14.9 9.0 1.6 8.8 4.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Tn7_Tnp_TnsA_C PF08721.11 CDJ66783.1 - 2.8 8.6 8.0 0.23 12.1 2.1 2.2 2 0 0 2 2 2 0 TnsA endonuclease C terminal Baculo_PEP_C PF04513.12 CDJ66784.1 - 4.1e-05 23.7 17.8 0.00011 22.3 17.8 1.7 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus BLM10_mid PF16507.5 CDJ66784.1 - 0.00087 18.1 1.8 0.0014 17.4 1.8 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region Utp14 PF04615.13 CDJ66784.1 - 0.1 11.1 21.0 0.15 10.6 21.0 1.2 1 0 0 1 1 1 0 Utp14 protein DUF948 PF06103.11 CDJ66784.1 - 1.5 9.1 12.2 0.044 14.1 4.6 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4795 PF16043.5 CDJ66784.1 - 2.8 7.5 28.3 0.053 13.1 20.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) SR-25 PF10500.9 CDJ66785.1 - 0.00028 20.6 23.2 0.0011 18.6 10.5 2.0 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF1180 PF06679.12 CDJ66785.1 - 0.012 16.1 5.2 0.012 16.1 5.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF4834 PF16118.5 CDJ66785.1 - 0.014 16.4 9.3 0.014 16.4 9.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) SID-1_RNA_chan PF13965.6 CDJ66785.1 - 0.047 12.1 5.9 0.059 11.8 5.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAGA-Tad1 PF12767.7 CDJ66785.1 - 0.062 13.0 16.3 0.085 12.6 16.3 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Caldesmon PF02029.15 CDJ66785.1 - 0.13 11.0 21.9 0.18 10.6 21.9 1.1 1 0 0 1 1 1 0 Caldesmon RskA PF10099.9 CDJ66785.1 - 0.18 12.1 13.2 0.27 11.5 13.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3408 PF11888.8 CDJ66785.1 - 0.61 10.2 20.0 0.77 9.9 10.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) CobT PF06213.12 CDJ66785.1 - 0.83 9.0 30.0 0.075 12.4 16.4 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT KASH PF10541.9 CDJ66785.1 - 0.93 9.8 7.6 1.2 9.4 3.1 2.2 2 0 0 2 2 2 0 Nuclear envelope localisation domain CCDC106 PF15794.5 CDJ66785.1 - 1.6 8.4 24.7 0.36 10.5 6.9 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 TRAP_alpha PF03896.16 CDJ66785.1 - 1.7 7.8 10.9 0.095 11.9 4.8 1.8 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit ABC2_membrane_2 PF12679.7 CDJ66785.1 - 2.4 7.3 4.5 0.75 9.0 1.7 1.5 1 1 1 2 2 2 0 ABC-2 family transporter protein SMYLE_N PF18615.1 CDJ66785.1 - 2.5 7.6 19.1 3.9 6.9 19.1 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF3807 PF12720.7 CDJ66785.1 - 2.5 8.3 31.9 0.91 9.8 17.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Activator_LAG-3 PF11498.8 CDJ66785.1 - 3.2 6.6 66.2 3.7 6.4 66.2 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4228 PF14009.6 CDJ66785.1 - 3.8 7.9 19.2 1.3 9.4 4.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) DUF5327 PF17261.2 CDJ66785.1 - 4.1 8.2 29.5 1 10.1 16.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF3381 PF11861.8 CDJ66785.1 - 4.4 7.1 22.1 5.9 6.7 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) TCP PF03634.13 CDJ66785.1 - 5.1 7.6 26.2 3.4 8.2 10.5 2.1 2 0 0 2 2 2 0 TCP family transcription factor Orf78 PF06024.12 CDJ66785.1 - 5.4 7.4 19.1 0.47 10.8 0.3 2.2 1 1 1 2 2 2 0 Orf78 (ac78) DUF4667 PF15700.5 CDJ66785.1 - 5.8 6.9 24.6 3.1 7.8 8.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) CCSAP PF15748.5 CDJ66785.1 - 5.9 7.0 30.1 10 6.2 30.1 1.3 1 1 0 1 1 1 0 Centriole, cilia and spindle-associated Syja_N PF02383.18 CDJ66786.1 - 1.3e-19 70.7 0.0 1.3e-19 70.7 0.0 5.8 5 2 1 6 6 6 3 SacI homology domain NAM-associated PF14303.6 CDJ66786.1 - 0.0064 17.2 1.5 0.0064 17.2 1.5 9.6 5 5 3 8 8 8 2 No apical meristem-associated C-terminal domain SR-25 PF10500.9 CDJ66787.1 - 0.047 13.3 8.3 0.077 12.6 8.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NUDE_C PF04880.13 CDJ66788.1 - 0.7 10.3 12.6 0.89 10.0 12.6 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region RVP_2 PF08284.11 CDJ66789.1 - 5.9e-10 39.0 0.0 8.3e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ66789.1 - 5.5e-09 36.5 0.0 8.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ66789.1 - 1.7e-08 35.0 0.0 2.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CDJ66789.1 - 0.00096 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 CDJ66789.1 - 0.19 11.2 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase zf-CCHC PF00098.23 CDJ66790.1 - 5.7e-07 29.3 2.8 5.7e-07 29.3 2.8 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ66790.1 - 0.012 15.4 1.4 0.028 14.2 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 CDJ66790.1 - 0.018 15.3 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein DnaJ_CXXCXGXG PF00684.19 CDJ66790.1 - 0.047 14.1 7.7 0.12 12.8 7.7 1.6 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_3 PF13917.6 CDJ66790.1 - 0.48 10.4 5.6 0.29 11.1 1.0 2.5 1 1 1 2 2 2 0 Zinc knuckle BTB_2 PF02214.22 CDJ66791.1 - 4.4e-15 55.8 0.3 3.1e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain APG6_N PF17675.1 CDJ66791.1 - 0.11 13.0 26.0 0.17 12.4 26.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0240 PF06784.11 CDJ66791.1 - 0.11 12.5 10.6 0.15 12.1 10.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) C1q PF00386.21 CDJ66791.1 - 0.19 12.0 2.5 0.17 12.1 0.8 1.8 1 1 1 2 2 2 0 C1q domain DUF740 PF05340.12 CDJ66791.1 - 0.39 9.4 7.0 0.41 9.3 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) AAA_11 PF13086.6 CDJ66791.1 - 0.7 9.6 11.8 0.94 9.2 11.8 1.1 1 0 0 1 1 1 0 AAA domain Band_3_cyto PF07565.13 CDJ66791.1 - 0.78 9.5 8.2 0.98 9.2 8.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FapA PF03961.13 CDJ66791.1 - 3.1 6.3 10.0 3.4 6.2 10.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4404 PF14357.6 CDJ66791.1 - 4 8.1 10.8 8.2 7.1 10.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) VIT1 PF01988.19 CDJ66791.1 - 5.1 6.9 5.6 6.8 6.5 5.6 1.2 1 0 0 1 1 1 0 VIT family Exonuc_VII_L PF02601.15 CDJ66791.1 - 8.7 5.8 12.6 10 5.6 12.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5401 PF17380.2 CDJ66791.1 - 9.1 4.2 22.3 12 3.8 22.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) MCM PF00493.23 CDJ66792.1 - 4.9e-48 163.2 0.0 6.6e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain AAA_5 PF07728.14 CDJ66792.1 - 2.7e-05 24.2 0.0 6.8e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ66792.1 - 0.047 14.1 2.8 0.26 11.6 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_60s PF00428.19 CDJ66792.1 - 4.2 8.0 18.0 0.54 10.9 7.4 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Dpy-30 PF05186.13 CDJ66793.1 - 2.5e-05 23.9 0.0 6.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif Neuregulin PF02158.15 CDJ66793.1 - 1.5 8.1 13.0 0.88 8.9 11.2 1.5 1 1 0 1 1 1 0 Neuregulin intracellular region FIBP PF05427.11 CDJ66794.1 - 0.00099 18.5 0.6 0.0018 17.7 0.6 1.4 1 1 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) Mei5_like PF17021.5 CDJ66794.1 - 0.024 14.7 0.3 0.053 13.6 0.3 1.6 1 1 0 1 1 1 0 Putative double-strand recombination repair-like Synuclein PF01387.17 CDJ66795.1 - 0.0023 18.1 0.0 0.0052 17.0 0.0 1.6 1 0 0 1 1 1 1 Synuclein AKAP28 PF14469.6 CDJ66795.1 - 0.043 13.6 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 28 kDa A-kinase anchor Trypsin_2 PF13365.6 CDJ66796.1 - 8.7e-18 65.7 0.1 1.7e-17 64.7 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 CDJ66796.1 - 3.2e-09 36.5 1.4 8e-09 35.2 1.4 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ66796.1 - 4.1e-07 30.3 0.0 9.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ66796.1 - 6.8e-06 26.3 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Peptidase_S29 PF02907.15 CDJ66796.1 - 0.0048 16.7 0.2 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Tricorn_PDZ PF14685.6 CDJ66796.1 - 0.03 14.3 0.1 0.068 13.1 0.1 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Trypsin PF00089.26 CDJ66796.1 - 0.13 12.0 0.0 0.4 10.5 0.0 1.8 1 1 0 1 1 1 0 Trypsin DUF2722 PF10846.8 CDJ66798.1 - 2e-05 23.8 9.9 2e-05 23.8 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ66798.1 - 0.0021 18.2 21.6 0.0023 18.0 21.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ66798.1 - 0.0034 17.0 24.5 0.0049 16.5 24.5 1.2 1 0 0 1 1 1 1 Spt20 family EPL1 PF10513.9 CDJ66798.1 - 0.0053 17.1 5.3 0.0067 16.8 5.3 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like AbLIM_anchor PF16182.5 CDJ66798.1 - 0.017 15.0 2.2 0.017 14.9 2.2 1.1 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM MscS_TM PF12794.7 CDJ66798.1 - 0.029 13.2 0.5 0.029 13.2 0.5 2.1 1 1 1 2 2 1 0 Mechanosensitive ion channel inner membrane domain 1 Nitroreductase PF00881.24 CDJ66798.1 - 0.081 13.0 5.4 0.1 12.6 5.4 1.2 1 0 0 1 1 1 0 Nitroreductase family PmbA_TldD PF01523.16 CDJ66798.1 - 0.095 12.5 0.4 0.11 12.3 0.4 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase BAF1_ABF1 PF04684.13 CDJ66798.1 - 0.13 11.3 7.6 0.16 11.0 7.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor YfhO PF09586.10 CDJ66798.1 - 0.19 9.9 2.5 0.2 9.9 2.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4770 PF15994.5 CDJ66798.1 - 0.24 11.7 10.4 0.29 11.4 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Ndc1_Nup PF09531.10 CDJ66798.1 - 0.28 9.8 6.3 0.29 9.8 6.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Gti1_Pac2 PF09729.9 CDJ66798.1 - 0.45 10.6 4.5 0.58 10.2 4.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Macoilin PF09726.9 CDJ66798.1 - 0.55 8.7 18.5 0.64 8.5 18.5 1.0 1 0 0 1 1 1 0 Macoilin family Med15 PF09606.10 CDJ66798.1 - 0.64 8.6 22.9 0.75 8.4 22.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 CDJ66798.1 - 0.65 8.7 9.5 0.74 8.5 9.5 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ66798.1 - 0.67 8.2 15.9 0.7 8.1 15.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.19 CDJ66798.1 - 0.67 10.6 16.1 0.29 11.7 13.5 1.7 2 0 0 2 2 1 0 60s Acidic ribosomal protein ALMT PF11744.8 CDJ66798.1 - 1.9 7.3 5.4 2.1 7.1 5.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter dCMP_cyt_deam_1 PF00383.23 CDJ66798.1 - 2.4 8.1 7.0 3.1 7.7 7.0 1.4 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Sec62 PF03839.16 CDJ66798.1 - 3.9 6.9 7.3 4.7 6.7 7.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 UPF0560 PF10577.9 CDJ66798.1 - 4.4 5.7 11.3 5 5.5 11.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TcA_TcB_BD PF18276.1 CDJ66798.1 - 7.3 5.6 16.6 9 5.3 16.6 1.1 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain CLN3 PF02487.17 CDJ66798.1 - 7.6 5.5 5.6 9.1 5.2 5.6 1.1 1 0 0 1 1 1 0 CLN3 protein ATAD4 PF15321.6 CDJ66798.1 - 7.7 7.9 9.5 18 6.7 9.5 1.7 1 1 0 1 1 1 0 ATPase family AAA domain containing 4 FliP PF00813.20 CDJ66798.1 - 8.1 6.3 7.6 8.3 6.2 6.8 1.4 2 0 0 2 2 1 0 FliP family NAD_synthase PF02540.17 CDJ66799.1 - 4.3e-28 98.1 0.0 2.9e-16 59.3 0.0 3.1 3 0 0 3 3 3 3 NAD synthase tRNA_Me_trans PF03054.16 CDJ66799.1 - 0.01 14.7 0.0 0.047 12.5 0.0 1.8 2 0 0 2 2 2 0 tRNA methyl transferase ATP_bind_3 PF01171.20 CDJ66799.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 PP-loop family DUF3446 PF11928.8 CDJ66800.1 - 0.0014 18.9 6.1 0.0014 18.9 6.1 1.5 2 0 0 2 2 2 1 Early growth response N-terminal domain DUF4667 PF15700.5 CDJ66800.1 - 0.0066 16.6 4.0 0.0077 16.4 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) CDK2AP PF09806.9 CDJ66800.1 - 0.011 15.8 3.2 0.015 15.4 3.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein TAN PF11640.8 CDJ66800.1 - 0.02 15.0 1.5 0.023 14.8 1.5 1.1 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Lin-8 PF03353.15 CDJ66800.1 - 0.036 13.6 1.8 0.044 13.4 1.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist E1-N PF14463.6 CDJ66800.1 - 0.11 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 E1 N-terminal domain DUF4598 PF15370.6 CDJ66800.1 - 0.71 10.4 5.2 0.38 11.2 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4598) HA2 PF04408.23 CDJ66801.1 - 2.6e-16 59.8 0.0 4.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDJ66801.1 - 7.8e-11 42.3 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SpoIIIAH PF12685.7 CDJ66802.1 - 0.00033 20.6 5.1 0.00033 20.6 5.1 4.7 2 1 1 3 3 3 1 SpoIIIAH-like protein Exonuc_VII_L PF02601.15 CDJ66802.1 - 0.00055 19.6 6.0 0.00055 19.6 6.0 3.3 2 1 1 3 3 3 1 Exonuclease VII, large subunit DUF913 PF06025.12 CDJ66802.1 - 0.0018 17.4 5.4 0.0018 17.4 5.4 4.8 2 1 0 2 2 2 1 Domain of Unknown Function (DUF913) BAF1_ABF1 PF04684.13 CDJ66802.1 - 0.002 17.3 5.2 0.002 17.3 5.2 5.2 4 1 1 5 5 5 1 BAF1 / ABF1 chromatin reorganising factor SAPS PF04499.15 CDJ66802.1 - 0.002 17.0 4.1 0.002 17.0 4.1 3.7 2 1 1 3 3 3 1 SIT4 phosphatase-associated protein SR-25 PF10500.9 CDJ66802.1 - 0.0022 17.6 40.8 0.0022 17.6 40.8 4.5 4 1 1 5 5 5 1 Nuclear RNA-splicing-associated protein Afi1 PF07792.12 CDJ66802.1 - 0.0046 17.4 9.7 0.0046 17.4 9.7 5.2 3 1 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Ribosomal_60s PF00428.19 CDJ66802.1 - 0.016 15.8 12.5 0.016 15.8 12.5 10.9 7 3 1 8 8 8 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ66802.1 - 1.3 9.3 167.3 0.2 11.9 17.2 9.4 4 2 3 7 7 7 0 Anti-sigma-K factor rskA Ubiq_cyt_C_chap PF03981.12 CDJ66804.1 - 4.1e-12 46.4 1.2 2.7e-05 24.3 0.0 3.2 3 0 0 3 3 3 2 Ubiquinol-cytochrome C chaperone DUF2722 PF10846.8 CDJ66805.1 - 0.0006 18.9 0.4 0.0006 18.9 0.4 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) DUF572 PF04502.13 CDJ66805.1 - 0.036 13.7 16.6 0.052 13.2 16.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SARAF PF06682.12 CDJ66805.1 - 0.067 12.8 9.6 0.11 12.2 9.6 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4638 PF15472.6 CDJ66805.1 - 0.18 11.5 14.2 0.36 10.5 14.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) V_ATPase_I PF01496.19 CDJ66805.1 - 0.24 9.3 12.8 0.28 9.0 12.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phosducin PF02114.16 CDJ66805.1 - 0.39 9.6 0.0 0.39 9.6 0.0 3.5 3 1 1 4 4 4 0 Phosducin Hid1 PF12722.7 CDJ66805.1 - 1.5 6.9 10.3 1.4 6.9 10.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NINJA_B PF16136.5 CDJ66805.1 - 1.7 9.0 18.1 0.28 11.6 11.0 2.6 2 1 0 2 2 2 0 Putative nuclear localisation signal Sec62 PF03839.16 CDJ66805.1 - 4.1 6.8 9.8 1.2 8.6 6.6 1.8 2 0 0 2 2 2 0 Translocation protein Sec62 LMBR1 PF04791.16 CDJ66805.1 - 8 5.2 6.5 11 4.8 6.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Wzz PF02706.15 CDJ66806.1 - 0.13 12.6 2.2 0.26 11.6 2.2 1.5 1 0 0 1 1 1 0 Chain length determinant protein Androgen_recep PF02166.16 CDJ66807.1 - 0.0024 16.8 9.9 0.0024 16.8 9.9 1.1 1 0 0 1 1 1 1 Androgen receptor RskA PF10099.9 CDJ66807.1 - 0.012 15.9 0.6 0.013 15.8 0.6 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ66807.1 - 0.029 14.0 8.7 0.028 14.1 8.7 1.1 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ66807.1 - 0.029 13.3 9.5 0.027 13.4 9.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ribosomal_60s PF00428.19 CDJ66807.1 - 0.077 13.6 0.1 0.085 13.5 0.1 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2967 PF11179.8 CDJ66807.1 - 2.3 6.2 7.8 2.4 6.1 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Med3 PF11593.8 CDJ66807.1 - 2.8 7.0 15.6 3.3 6.8 15.6 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2722 PF10846.8 CDJ66807.1 - 8.4 5.2 11.4 9.5 5.0 11.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2722 PF10846.8 CDJ66808.1 - 0.0018 17.3 4.7 0.0018 17.3 4.7 6.9 3 1 3 6 6 6 1 Protein of unknown function (DUF2722) SPX PF03105.19 CDJ66808.1 - 0.0028 17.6 10.3 0.0028 17.6 10.3 3.7 2 1 1 3 3 3 1 SPX domain DUF4667 PF15700.5 CDJ66808.1 - 0.022 14.9 1.1 0.022 14.9 1.1 5.9 5 1 1 6 6 6 0 Domain of unknown function (DUF4667) Abhydrolase_3 PF07859.13 CDJ66809.1 - 4.1e-33 115.0 0.0 4.1e-33 115.0 0.0 3.8 3 2 1 4 4 4 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDJ66809.1 - 2.7e-11 42.9 0.0 2.7e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase GYF PF02213.16 CDJ66810.1 - 2.2e-08 33.6 0.2 3.6e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 GYF domain DUF746 PF05344.11 CDJ66811.1 - 0.011 15.6 0.3 0.025 14.4 0.3 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) HTH_23 PF13384.6 CDJ66811.1 - 0.017 14.9 0.2 0.017 14.9 0.2 2.5 3 0 0 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.6 CDJ66811.1 - 0.02 15.0 0.2 0.02 15.0 0.2 3.7 5 1 0 5 5 5 0 Helix-turn-helix domain PhoH PF02562.16 CDJ66811.1 - 0.12 11.8 1.1 0.19 11.2 1.1 1.3 1 0 0 1 1 1 0 PhoH-like protein HTH_Tnp_1 PF01527.20 CDJ66811.1 - 2.6 8.4 12.8 1.5 9.2 2.4 3.4 2 2 2 4 4 4 0 Transposase DUF2368 PF10166.9 CDJ66812.1 - 0.00053 19.6 7.3 0.00059 19.5 7.3 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) Androgen_recep PF02166.16 CDJ66812.1 - 0.44 9.3 12.2 0.45 9.3 12.2 1.1 1 0 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 CDJ66812.1 - 0.97 9.0 12.6 1 9.0 12.6 1.1 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ66813.1 - 0.0051 16.5 31.7 0.0062 16.2 31.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Hamartin PF04388.12 CDJ66813.1 - 3.4 6.2 28.0 3.9 6.0 28.0 1.1 1 0 0 1 1 1 0 Hamartin protein FSA_C PF10479.9 CDJ66813.1 - 7.1 4.6 13.9 7.8 4.5 13.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RT_RNaseH_2 PF17919.1 CDJ66814.1 - 1.5e-29 102.0 0.0 3.1e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ66814.1 - 1.1e-28 99.6 0.0 2.8e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ66814.1 - 4.2e-21 75.5 0.0 7e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CDJ66814.1 - 1.8e-08 34.3 0.0 3.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ66814.1 - 1e-07 32.5 0.0 2.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ66814.1 - 2e-07 31.5 0.0 3.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF3552 PF12072.8 CDJ66814.1 - 0.0089 15.5 0.2 0.013 14.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Asp_protease PF09668.10 CDJ66814.1 - 0.027 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 CDJ66814.1 - 0.03 14.6 0.0 0.12 12.7 0.0 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 CDJ66815.1 - 3.7e-07 30.3 0.1 1.1e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 CDJ66815.1 - 4.9e-06 26.4 15.4 3.7e-05 23.6 2.6 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ66815.1 - 0.031 14.1 0.8 0.031 14.1 0.8 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ66815.1 - 0.46 10.5 7.6 0.15 12.0 0.8 2.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ66815.1 - 0.55 10.0 10.7 0.71 9.6 2.1 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 CDJ66815.1 - 0.79 9.6 9.4 0.35 10.7 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ66815.1 - 1 9.1 6.0 2.3 8.0 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CDJ66815.1 - 1.4 9.3 10.6 3.5 8.0 10.6 1.6 1 1 0 1 1 1 0 DnaJ central domain Spt20 PF12090.8 CDJ66817.1 - 0.14 11.7 11.9 0.22 11.1 11.9 1.2 1 0 0 1 1 1 0 Spt20 family DEAD PF00270.29 CDJ66818.1 - 5.7e-42 143.5 0.0 6.6e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ66818.1 - 6.7e-05 23.0 0.0 9.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ66818.1 - 0.15 12.4 0.3 3.8 7.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain Ribosomal_L3 PF00297.22 CDJ66819.1 - 1.9e-172 573.3 2.7 2.2e-172 573.1 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RNA_pol_Rpb2_3 PF04565.16 CDJ66821.1 - 7.9e-27 93.2 0.0 1.9e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 CDJ66821.1 - 9.5e-27 93.8 0.0 1.4e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CDJ66821.1 - 0.16 11.6 0.0 0.43 10.2 0.0 1.8 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_6 PF00562.28 CDJ66822.1 - 1.3e-116 389.9 0.0 1.8e-116 389.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 CDJ66822.1 - 1.1e-13 51.4 0.0 2.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Rad50_zn_hook PF04423.14 CDJ66822.1 - 0.14 12.0 0.5 0.26 11.1 0.5 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif Lactamase_B_2 PF12706.7 CDJ66825.1 - 1.8e-06 27.6 3.6 0.00029 20.4 0.3 3.7 2 2 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ66825.1 - 0.00028 21.0 0.2 0.0023 18.0 0.1 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RRM_1 PF00076.22 CDJ66826.1 - 4.3e-08 32.9 0.0 6.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ66826.1 - 0.032 14.1 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif SUIM_assoc PF16619.5 CDJ66828.1 - 0.0093 16.0 0.5 0.0093 16.0 0.5 14.6 9 3 2 11 11 11 6 Unstructured region C-term to UIM in Ataxin3 DUF2182 PF09948.9 CDJ66829.1 - 0.11 12.4 0.8 0.17 11.7 0.8 1.3 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) Arteri_nucleo PF01481.16 CDJ66829.1 - 3.8 7.8 9.0 0.28 11.5 3.3 1.9 2 1 0 2 2 2 0 Arterivirus nucleocapsid protein RAP1 PF07218.11 CDJ66830.1 - 0.0064 14.8 3.2 0.0089 14.4 3.2 1.2 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Spt20 PF12090.8 CDJ66830.1 - 0.21 11.2 33.6 0.55 9.8 6.0 3.1 3 0 0 3 3 3 0 Spt20 family DUF1645 PF07816.11 CDJ66830.1 - 1.8 9.1 15.6 0.95 10.0 7.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Mid2 PF04478.12 CDJ66830.1 - 3.7 7.4 0.0 3.7 7.4 0.0 3.2 3 1 0 3 3 3 0 Mid2 like cell wall stress sensor Secretin_N_2 PF07655.13 CDJ66830.1 - 5.5 7.6 15.4 0.6 10.7 10.3 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain Peptidase_C14 PF00656.22 CDJ66832.1 - 3.9e-08 33.5 0.0 4.9e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Spt20 PF12090.8 CDJ66832.1 - 0.00037 20.2 6.6 0.00037 20.2 6.6 1.1 1 0 0 1 1 1 1 Spt20 family Androgen_recep PF02166.16 CDJ66832.1 - 0.0028 16.6 12.5 0.0036 16.2 12.5 1.1 1 0 0 1 1 1 1 Androgen receptor Noggin PF05806.12 CDJ66832.1 - 0.0032 17.4 0.3 0.0039 17.1 0.3 1.1 1 0 0 1 1 1 1 Noggin Med15 PF09606.10 CDJ66832.1 - 0.049 12.3 9.6 0.049 12.3 9.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Vac7 PF12751.7 CDJ66832.1 - 0.098 12.1 0.4 0.11 11.9 0.4 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF2722 PF10846.8 CDJ66832.1 - 0.15 11.0 10.4 0.19 10.6 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Conotoxin PF02950.17 CDJ66832.1 - 2.6 9.1 5.2 4 8.5 5.2 1.2 1 0 0 1 1 1 0 Conotoxin SUIM_assoc PF16619.5 CDJ66832.1 - 2.8 8.1 22.4 4.4e+02 1.0 22.4 2.3 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 CDJ66835.1 - 0.001 17.9 5.4 0.001 17.9 5.4 3.5 3 1 0 3 3 3 1 Presenilin DUF2722 PF10846.8 CDJ66835.1 - 0.0019 17.2 12.4 0.0019 17.2 12.4 6.0 4 2 0 4 4 4 2 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ66835.1 - 0.0023 17.6 7.0 0.0023 17.6 7.0 6.3 5 1 0 6 6 6 1 Nuclear RNA-splicing-associated protein DUF4667 PF15700.5 CDJ66835.1 - 5 7.1 40.0 0.21 11.7 16.8 4.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4667) Prefoldin_2 PF01920.20 CDJ66836.1 - 1.7e-09 37.6 0.1 1.7e-09 37.6 0.1 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF755 PF05501.11 CDJ66836.1 - 0.00038 20.7 21.5 0.00038 20.7 21.5 1.6 2 0 0 2 2 1 1 Domain of unknown function (DUF755) DUF3824 PF12868.7 CDJ66836.1 - 0.0038 17.9 12.5 0.0052 17.5 12.5 1.2 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) DUF4386 PF14329.6 CDJ66836.1 - 0.012 15.5 1.0 0.014 15.3 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Paf1 PF03985.13 CDJ66836.1 - 0.025 13.6 6.9 0.023 13.7 6.9 1.1 1 0 0 1 1 1 0 Paf1 API5 PF05918.11 CDJ66836.1 - 0.027 13.3 7.3 0.026 13.3 7.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CPSF100_C PF13299.6 CDJ66836.1 - 0.043 14.0 7.7 0.052 13.7 7.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PAP1 PF08601.10 CDJ66836.1 - 0.14 11.9 15.9 0.14 11.9 15.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Presenilin PF01080.17 CDJ66836.1 - 0.15 10.8 12.4 0.18 10.6 12.4 1.1 1 0 0 1 1 1 0 Presenilin CD20 PF04103.15 CDJ66836.1 - 0.15 12.1 2.0 0.18 11.9 2.0 1.2 1 0 0 1 1 1 0 CD20-like family Spem1 PF15670.5 CDJ66836.1 - 0.16 11.5 7.4 0.21 11.1 7.4 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Band_3_cyto PF07565.13 CDJ66836.1 - 0.2 11.5 7.2 0.21 11.3 7.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Apt1 PF10351.9 CDJ66836.1 - 0.2 10.5 9.2 0.19 10.5 9.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RskA PF10099.9 CDJ66836.1 - 0.21 11.9 18.2 0.34 11.2 18.2 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Connexin PF00029.19 CDJ66836.1 - 0.42 10.3 3.3 0.5 10.1 3.3 1.1 1 0 0 1 1 1 0 Connexin TMEM151 PF14857.6 CDJ66836.1 - 0.44 9.4 7.4 0.42 9.5 7.4 1.2 1 0 0 1 1 1 0 TMEM151 family SR-25 PF10500.9 CDJ66836.1 - 0.59 9.7 28.7 1.1 8.9 28.7 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mem_trans PF03547.18 CDJ66836.1 - 0.65 8.3 4.2 0.63 8.4 4.2 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF3138 PF11336.8 CDJ66836.1 - 0.75 8.3 14.8 0.93 8.0 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DDHD PF02862.17 CDJ66836.1 - 0.78 9.9 10.8 0.83 9.8 10.8 1.2 1 0 0 1 1 1 0 DDHD domain NDUF_B12 PF08122.12 CDJ66836.1 - 0.85 9.7 2.6 1.8 8.6 2.6 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family TFIIA PF03153.13 CDJ66836.1 - 0.87 9.5 23.8 0.97 9.4 23.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3801 PF12687.7 CDJ66836.1 - 0.89 9.6 12.3 0.34 10.9 10.1 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3801) GREB1 PF15782.5 CDJ66836.1 - 1 6.4 19.0 1.1 6.3 19.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PepSY_2 PF13670.6 CDJ66836.1 - 1.1 9.3 12.9 2.1 8.4 12.9 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Spt20 PF12090.8 CDJ66836.1 - 1.1 8.8 20.4 1.4 8.5 20.4 1.2 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 CDJ66836.1 - 1.1 9.3 6.5 1.2 9.1 6.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CCDC106 PF15794.5 CDJ66836.1 - 1.3 8.7 14.1 1.8 8.2 14.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 NEMP PF10225.9 CDJ66836.1 - 1.4 8.5 4.3 1.6 8.3 4.3 1.1 1 0 0 1 1 1 0 NEMP family DUF3450 PF11932.8 CDJ66836.1 - 1.5 8.1 19.6 0.58 9.4 14.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SARAF PF06682.12 CDJ66836.1 - 1.9 8.0 13.4 2.2 7.8 13.4 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Macoilin PF09726.9 CDJ66836.1 - 2.3 6.6 13.8 2.4 6.6 13.8 1.1 1 0 0 1 1 1 0 Macoilin family Ribosomal_60s PF00428.19 CDJ66836.1 - 2.8 8.6 21.8 5.5 7.7 21.8 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein EIIBC-GUT_N PF03612.14 CDJ66836.1 - 3.2 7.4 6.8 4.7 6.9 6.8 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF5521 PF17659.1 CDJ66836.1 - 4.2 5.1 11.2 5 4.9 11.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) BAF1_ABF1 PF04684.13 CDJ66836.1 - 4.9 6.1 19.9 6.6 5.7 20.0 1.3 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4407 PF14362.6 CDJ66836.1 - 7.7 5.8 18.0 9.3 5.5 18.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Roughex PF06020.11 CDJ66836.1 - 7.9 5.5 14.7 2.3 7.2 11.4 1.7 2 0 0 2 2 2 0 Drosophila roughex protein EMC1_C PF07774.13 CDJ66837.1 - 7.2e-31 107.5 0.0 8.1e-24 84.5 0.0 2.6 2 0 0 2 2 2 2 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CDJ66837.1 - 0.00032 20.4 22.0 0.011 15.3 12.8 3.2 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 CDJ66837.1 - 0.0032 17.3 1.6 8.9 6.4 0.1 3.9 4 0 0 4 4 4 1 PQQ enzyme repeat Collagen PF01391.18 CDJ66837.1 - 0.011 15.5 45.7 0.033 13.9 22.7 2.5 1 1 1 2 2 2 0 Collagen triple helix repeat (20 copies) Peroxin-22 PF12827.7 CDJ66837.1 - 0.043 13.7 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family ABC2_membrane PF01061.24 CDJ66838.1 - 1.1e-16 60.9 26.4 1.1e-13 51.1 19.3 2.6 1 1 1 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CDJ66838.1 - 0.00033 21.2 0.0 0.00033 21.2 0.0 2.9 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 CDJ66838.1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4834 PF16118.5 CDJ66840.1 - 0.061 14.3 1.2 0.061 14.3 1.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Folate_carrier PF01770.18 CDJ66840.1 - 0.065 12.0 0.4 0.1 11.3 0.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF966 PF06136.13 CDJ66840.1 - 0.26 10.9 19.3 0.39 10.4 19.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) EF-hand_6 PF13405.6 CDJ66843.1 - 0.00014 21.5 0.2 0.024 14.6 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CDJ66843.1 - 0.00015 21.1 0.2 0.02 14.4 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 CDJ66843.1 - 0.00017 21.9 0.1 0.033 14.6 0.0 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ66843.1 - 0.0028 17.1 0.8 0.084 12.4 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CDJ66843.1 - 0.18 11.6 0.1 7.8 6.4 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain pair DnaJ_C PF01556.18 CDJ66844.1 - 3.4e-44 150.5 0.3 5.1e-44 149.9 0.3 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ66844.1 - 5.9e-19 68.0 2.7 1.1e-18 67.1 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain ParE_toxin PF05016.15 CDJ66844.1 - 0.16 12.6 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE TPT PF03151.16 CDJ66845.1 - 6.1e-07 29.1 6.0 6.1e-07 29.1 6.0 1.6 2 0 0 2 2 2 1 Triose-phosphate Transporter family PUNUT PF16913.5 CDJ66845.1 - 9.1e-06 25.1 14.4 2.7e-05 23.5 14.4 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 CDJ66845.1 - 1.1e-05 24.8 2.4 1.8e-05 24.1 2.4 1.4 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDJ66845.1 - 0.00029 21.0 5.6 0.00029 21.0 5.6 3.8 3 2 1 4 4 4 1 EamA-like transporter family CRT-like PF08627.10 CDJ66845.1 - 0.00099 18.2 1.1 0.0013 17.7 1.1 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 CDJ66845.1 - 0.0021 17.3 4.8 0.0053 16.0 4.8 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter HlyIII PF03006.20 CDJ66845.1 - 0.034 13.9 10.9 0.012 15.3 8.1 1.7 2 1 0 2 2 2 0 Haemolysin-III related Herpes_UL79 PF03049.14 CDJ66845.1 - 0.042 13.5 0.1 0.068 12.8 0.1 1.3 1 0 0 1 1 1 0 UL79 family DUF1129 PF06570.11 CDJ66845.1 - 2.4 7.6 6.7 4.6 6.7 6.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Porphobil_deamC PF03900.15 CDJ66846.1 - 0.02 15.3 0.0 0.062 13.7 0.0 1.8 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain AP2 PF00847.20 CDJ66846.1 - 0.027 14.7 0.4 0.052 13.8 0.0 1.6 2 0 0 2 2 2 0 AP2 domain Stathmin PF00836.19 CDJ66846.1 - 0.75 9.8 3.8 1.7 8.6 3.8 1.5 1 0 0 1 1 1 0 Stathmin family Inj_translocase PF16928.5 CDJ66846.1 - 4 6.8 7.0 1.6 8.1 1.0 2.3 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome PAP_assoc PF03828.19 CDJ66849.1 - 6.3e-09 35.9 0.0 6.3e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CDJ66849.1 - 0.00023 21.4 0.0 0.0046 17.2 0.0 2.4 2 0 0 2 2 2 1 Nucleotidyltransferase domain Senescence PF06911.12 CDJ66849.1 - 0.026 14.9 2.4 5.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Senescence-associated protein Patched PF02460.18 CDJ66850.1 - 8.5e-105 351.6 4.9 6.4e-55 186.6 0.0 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDJ66850.1 - 1.3e-30 106.2 6.6 1.3e-30 106.2 6.6 2.6 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation CRAL_TRIO_2 PF13716.6 CDJ66854.1 - 0.0082 16.3 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CDJ66854.1 - 0.014 15.1 0.0 0.047 13.4 0.0 1.8 1 1 0 1 1 1 0 CRAL/TRIO domain HAGH_C PF16123.5 CDJ66855.1 - 1.2e-29 102.7 0.2 1.7e-29 102.1 0.2 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CDJ66855.1 - 2.1e-08 34.4 0.3 4.2e-08 33.4 0.2 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily UPF0139 PF03669.13 CDJ66856.1 - 1.4e-07 31.2 0.0 1.9e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Mito_carr PF00153.27 CDJ66858.1 - 7.8e-35 118.7 0.1 3.2e-17 62.2 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.27 CDJ66859.1 - 2.3e-18 65.9 0.0 2.5e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein zf-CCCH PF00642.24 CDJ66862.1 - 4.2e-09 36.1 16.4 0.00011 22.1 0.8 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDJ66862.1 - 1.6e-05 25.6 13.9 0.039 14.6 0.0 3.5 1 1 2 3 3 3 3 Torus domain zf-CCCH_3 PF15663.5 CDJ66862.1 - 2.3e-05 24.6 9.9 0.0056 16.9 3.0 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 CDJ66862.1 - 0.0041 16.9 22.7 0.045 13.6 5.7 3.9 3 1 0 3 3 3 2 CCCH-type zinc finger zf-C3H1 PF10650.9 CDJ66862.1 - 0.0043 16.8 4.3 0.12 12.2 1.7 2.5 2 0 0 2 2 2 1 Putative zinc-finger domain zf-CCCH_2 PF14608.6 CDJ66862.1 - 0.022 15.2 0.9 0.022 15.2 0.9 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CDJ66862.1 - 0.18 11.9 25.8 0.6 10.2 3.6 4.2 3 1 0 3 3 3 0 Zinc finger domain DUF1664 PF07889.12 CDJ66863.1 - 0.002 18.2 5.0 0.002 18.2 5.0 10.3 6 2 4 10 10 10 1 Protein of unknown function (DUF1664) KELK PF15796.5 CDJ66863.1 - 0.011 16.1 6.2 0.011 16.1 6.2 14.1 4 3 6 13 13 13 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MtrB PF05440.12 CDJ66863.1 - 0.64 10.5 1.9 48 4.5 0.1 4.0 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B TAT_signal PF10518.9 CDJ66864.1 - 0.02 14.7 8.6 0.1 12.4 8.6 2.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Pkinase PF00069.25 CDJ66865.1 - 1.3e-41 142.7 0.0 6.8e-28 97.8 0.0 3.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ66865.1 - 1.5e-17 63.7 0.0 1.8e-15 56.9 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_7 PF13499.6 CDJ66865.1 - 2.3e-13 50.4 0.0 7.2e-06 26.4 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ66865.1 - 2.6e-13 48.5 0.8 0.016 14.7 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDJ66865.1 - 4.1e-10 38.8 3.2 0.0078 16.1 0.0 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CDJ66865.1 - 3.5e-07 30.0 3.4 0.26 11.1 0.3 4.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ66865.1 - 3.7e-05 23.0 13.5 2.3 7.9 0.0 5.2 6 0 0 6 6 6 4 EF hand Kinase-like PF14531.6 CDJ66865.1 - 0.0034 16.7 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like CSG2 PF16965.5 CDJ66865.1 - 3.3 6.6 5.6 6.5 5.6 1.8 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator Presenilin PF01080.17 CDJ66865.1 - 5.3 5.7 22.5 5.6 5.6 1.8 2.5 2 0 0 2 2 2 0 Presenilin Bromodomain PF00439.25 CDJ66866.1 - 2.1e-15 56.5 0.0 4.6e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Bromodomain SET PF00856.28 CDJ66866.1 - 3.8e-15 56.7 0.0 3.8e-15 56.7 0.0 10.3 7 3 1 8 8 8 1 SET domain PHD PF00628.29 CDJ66866.1 - 3.4e-05 23.6 2.2 3.4e-05 23.6 2.2 9.9 9 2 1 10 10 10 5 PHD-finger FYRN PF05964.14 CDJ66866.1 - 0.0032 17.3 0.0 0.013 15.4 0.0 2.0 1 0 0 1 1 1 1 F/Y-rich N-terminus ABC_tran PF00005.27 CDJ66867.1 - 2.6e-42 144.6 27.4 8.2e-21 75.0 0.1 4.0 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CDJ66867.1 - 4.3e-19 69.5 0.0 4.5e-05 23.4 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ66867.1 - 2.5e-11 43.5 19.6 1.6e-06 27.7 5.5 4.3 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ66867.1 - 6.7e-11 41.8 0.1 0.00045 19.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 CDJ66867.1 - 5e-09 36.0 1.2 0.0013 18.3 0.2 3.4 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 CDJ66867.1 - 2.1e-07 30.8 5.2 0.0012 18.6 0.4 3.3 3 0 0 3 3 2 2 IstB-like ATP binding protein T2SSE PF00437.20 CDJ66867.1 - 4.6e-07 29.2 2.9 0.00064 18.9 0.0 3.1 3 0 0 3 3 3 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 CDJ66867.1 - 7e-07 29.3 0.0 0.0092 16.1 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 CDJ66867.1 - 3.5e-06 27.0 6.1 0.022 14.5 0.0 3.1 3 1 1 4 4 2 2 AAA ATPase domain AAA_33 PF13671.6 CDJ66867.1 - 4.4e-06 26.9 14.9 0.11 12.7 0.8 4.4 4 0 0 4 4 3 3 AAA domain AAA_23 PF13476.6 CDJ66867.1 - 4.9e-06 27.2 4.9 0.00024 21.7 0.4 6.0 2 2 1 3 3 2 2 AAA domain cobW PF02492.19 CDJ66867.1 - 8.1e-06 25.5 2.2 0.39 10.3 0.0 3.9 4 0 0 4 4 4 2 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 CDJ66867.1 - 8.8e-06 26.2 0.0 0.25 11.7 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 CDJ66867.1 - 1e-05 25.7 8.0 0.013 15.7 0.3 3.5 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CDJ66867.1 - 1.4e-05 25.1 14.5 0.0037 17.2 0.8 3.3 3 0 0 3 3 3 2 RsgA GTPase NACHT PF05729.12 CDJ66867.1 - 3.3e-05 23.9 2.6 0.0012 18.8 0.2 4.6 4 2 0 4 4 3 2 NACHT domain PduV-EutP PF10662.9 CDJ66867.1 - 3.7e-05 23.5 0.2 0.097 12.4 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 CDJ66867.1 - 4.2e-05 23.9 1.1 0.17 12.3 0.0 3.0 3 0 0 3 3 2 2 RNA helicase GTP_EFTU PF00009.27 CDJ66867.1 - 0.00011 21.7 6.2 0.06 12.9 0.2 3.5 3 1 1 4 4 4 2 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 CDJ66867.1 - 0.00014 21.4 2.0 0.41 10.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 CDJ66867.1 - 0.00015 22.3 0.0 0.16 12.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CDJ66867.1 - 0.0002 21.3 2.4 0.29 11.1 0.4 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) TsaE PF02367.17 CDJ66867.1 - 0.00028 20.9 1.3 0.15 12.1 0.2 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 CDJ66867.1 - 0.00029 20.3 1.6 0.61 9.4 0.2 2.9 2 1 0 2 2 2 2 FtsK/SpoIIIE family Mg_chelatase PF01078.21 CDJ66867.1 - 0.00032 20.1 1.1 0.41 10.0 0.4 2.9 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CDJ66867.1 - 0.00041 20.4 0.8 1.1 9.4 0.1 2.9 2 0 0 2 2 2 2 AAA domain Septin PF00735.18 CDJ66867.1 - 0.00044 19.6 8.6 0.015 14.6 0.3 3.0 2 1 1 3 3 3 2 Septin Arf PF00025.21 CDJ66867.1 - 0.00062 19.3 0.2 0.39 10.2 0.1 2.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Rad17 PF03215.15 CDJ66867.1 - 0.00083 19.3 1.9 1.3 8.9 0.1 2.8 2 0 0 2 2 2 2 Rad17 P-loop domain DUF815 PF05673.13 CDJ66867.1 - 0.0011 18.2 2.4 0.65 9.1 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NTPase_1 PF03266.15 CDJ66867.1 - 0.0015 18.5 0.1 1.9 8.4 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_24 PF13479.6 CDJ66867.1 - 0.0019 18.0 3.8 0.25 11.0 0.1 3.1 3 1 0 3 3 2 1 AAA domain SRP54 PF00448.22 CDJ66867.1 - 0.0032 17.1 7.3 0.18 11.4 0.1 3.4 3 0 0 3 3 2 2 SRP54-type protein, GTPase domain G-alpha PF00503.20 CDJ66867.1 - 0.0035 16.6 0.4 0.0035 16.6 0.4 2.7 2 1 0 2 2 1 1 G-protein alpha subunit ATPase_2 PF01637.18 CDJ66867.1 - 0.0036 17.3 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CDJ66867.1 - 0.0049 17.1 17.5 0.013 15.8 0.0 4.3 4 1 1 5 5 3 2 AAA domain MobB PF03205.14 CDJ66867.1 - 0.0072 16.2 0.1 5.9 6.8 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 CDJ66867.1 - 0.0093 16.3 3.5 0.63 10.4 0.0 3.4 3 1 0 3 3 2 1 AAA domain Ploopntkinase3 PF18751.1 CDJ66867.1 - 0.011 15.7 0.2 3 7.7 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF599 PF04654.12 CDJ66867.1 - 0.013 14.9 1.3 0.04 13.3 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF599 ATP-synt_ab PF00006.25 CDJ66867.1 - 0.013 15.2 0.1 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 CDJ66867.1 - 0.016 15.0 0.0 3.5 7.3 0.0 2.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 CDJ66867.1 - 0.019 15.2 0.0 0.019 15.2 0.0 5.6 5 2 0 5 5 3 0 AAA domain Pox_A32 PF04665.12 CDJ66867.1 - 0.03 13.8 0.0 8.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein NB-ARC PF00931.22 CDJ66867.1 - 0.046 12.9 6.1 1.9 7.6 0.0 3.3 4 0 0 4 4 3 0 NB-ARC domain FeoB_N PF02421.18 CDJ66867.1 - 0.053 13.0 0.2 8.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Cytidylate_kin PF02224.18 CDJ66867.1 - 0.06 13.1 2.4 0.22 11.2 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase MeaB PF03308.16 CDJ66867.1 - 0.065 12.2 11.2 0.24 10.3 0.0 3.1 4 0 0 4 4 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 CDJ66867.1 - 0.098 12.4 0.3 17 5.0 0.1 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.26 CDJ66867.1 - 0.11 12.2 8.4 1 9.1 0.4 3.4 3 1 1 4 4 4 0 Sigma-54 interaction domain Dynamin_N PF00350.23 CDJ66867.1 - 0.25 11.4 0.1 0.25 11.4 0.1 5.1 5 2 1 6 6 5 0 Dynamin family Bac_DnaA PF00308.18 CDJ66867.1 - 0.33 10.8 3.8 0.47 10.2 0.1 2.6 3 0 0 3 3 2 0 Bacterial dnaA protein AAA_16 PF13191.6 CDJ66867.1 - 0.37 11.1 51.0 0.15 12.4 7.7 4.8 2 2 1 4 4 4 0 AAA ATPase domain AAA_27 PF13514.6 CDJ66867.1 - 0.65 9.5 0.0 0.65 9.5 0.0 4.6 4 2 0 4 4 4 0 AAA domain AAA_17 PF13207.6 CDJ66867.1 - 2.7 8.4 8.9 12 6.3 0.1 3.5 3 1 1 4 4 2 0 AAA domain AAA_13 PF13166.6 CDJ66867.1 - 6.9 5.2 26.5 0.8 8.3 0.0 4.8 3 1 0 3 3 2 0 AAA domain His_Phos_1 PF00300.22 CDJ66868.1 - 7.7e-13 48.6 10.3 1.9e-09 37.5 5.2 4.2 2 2 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) RskA PF10099.9 CDJ66868.1 - 0.0012 19.1 4.2 0.0012 19.1 4.2 3.4 2 1 0 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ66870.1 - 0.0061 16.6 3.8 0.0078 16.3 3.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ66870.1 - 0.0074 15.3 5.8 0.011 14.8 5.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4518 PF15008.6 CDJ66870.1 - 0.0084 15.3 0.1 0.012 14.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) HEAT PF02985.22 CDJ66871.1 - 1.9e-14 52.5 23.5 6.9e-05 22.8 0.0 10.9 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.6 CDJ66871.1 - 1.2e-13 51.3 0.2 5.8e-08 33.0 0.0 9.4 5 4 6 11 11 10 4 HEAT repeats Vac14_Fab1_bd PF12755.7 CDJ66871.1 - 6.5e-12 45.9 0.7 0.00079 20.0 0.0 5.5 5 1 2 7 7 6 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CDJ66871.1 - 1.7e-10 41.1 6.1 3.1e-06 27.5 0.1 11.9 10 4 5 15 15 11 3 HEAT-like repeat Cnd1 PF12717.7 CDJ66871.1 - 3.5e-08 33.7 0.0 6.3e-06 26.3 0.0 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Importin_rep_4 PF18808.1 CDJ66871.1 - 2.3e-07 31.0 0.0 2.3e-07 31.0 0.0 2.6 2 0 0 2 2 1 1 Importin repeat Arm PF00514.23 CDJ66871.1 - 2.8e-05 24.0 15.3 2.2 8.5 0.0 8.6 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 CDJ66871.1 - 0.00038 20.1 2.4 0.64 9.5 0.0 5.1 4 2 0 4 4 4 1 Tti2 family CLASP_N PF12348.8 CDJ66871.1 - 0.00045 19.8 0.3 0.0066 16.0 0.0 3.1 3 0 0 3 3 3 1 CLASP N terminal Adaptin_N PF01602.20 CDJ66871.1 - 0.00046 18.9 0.2 0.029 12.9 0.3 3.2 2 1 0 2 2 2 1 Adaptin N terminal region Ecm29 PF13001.7 CDJ66871.1 - 0.003 16.3 0.8 0.14 10.8 0.0 2.8 2 1 0 2 2 2 1 Proteasome stabiliser RTP1_C1 PF10363.9 CDJ66871.1 - 0.074 13.2 0.2 6.8 6.9 0.0 4.0 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 SopA_C PF13979.6 CDJ66871.1 - 0.098 12.4 0.0 0.098 12.4 0.0 2.5 4 0 0 4 4 4 0 SopA-like catalytic domain Spore_III_AB PF09548.10 CDJ66871.1 - 1.2 9.2 4.1 1.3 9.1 0.1 3.2 4 0 0 4 4 3 0 Stage III sporulation protein AB (spore_III_AB) FANCI_S1 PF14675.6 CDJ66871.1 - 5.4 6.5 7.8 16 5.0 0.2 4.8 5 1 1 6 6 6 0 FANCI solenoid 1 Prefoldin_2 PF01920.20 CDJ66872.1 - 2.5e-19 69.2 2.7 2.5e-19 69.2 2.7 1.6 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin PF02996.17 CDJ66872.1 - 6.2e-05 22.9 0.9 0.13 12.2 0.1 2.2 2 0 0 2 2 2 2 Prefoldin subunit DUF1043 PF06295.12 CDJ66872.1 - 0.0019 18.2 1.9 0.0019 18.2 1.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1043) Helo_like_N PF17111.5 CDJ66872.1 - 0.0045 16.4 6.4 0.012 15.0 0.5 2.1 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins Filament PF00038.21 CDJ66872.1 - 0.0067 16.0 5.2 0.035 13.7 0.5 2.2 2 0 0 2 2 2 1 Intermediate filament protein DUF615 PF04751.14 CDJ66872.1 - 0.011 15.7 5.4 0.016 15.2 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF615) APG6_N PF17675.1 CDJ66872.1 - 0.018 15.6 11.8 0.12 12.9 0.3 2.2 2 1 0 2 2 2 0 Apg6 coiled-coil region Acyl-CoA_dh_C PF12806.7 CDJ66872.1 - 0.022 14.9 3.6 0.037 14.2 2.6 1.7 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like LytTR PF04397.15 CDJ66872.1 - 0.026 14.8 0.5 0.71 10.1 0.1 2.1 1 1 1 2 2 2 0 LytTr DNA-binding domain DUF1319 PF07028.11 CDJ66872.1 - 0.028 14.6 1.7 0.055 13.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DASH_Dad3 PF08656.10 CDJ66872.1 - 0.032 14.3 1.0 1.5 8.9 0.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4407 PF14362.6 CDJ66872.1 - 0.043 13.2 8.1 0.095 12.0 8.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MscS_porin PF12795.7 CDJ66872.1 - 0.043 13.3 0.9 0.043 13.3 0.9 2.6 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain CLZ PF16526.5 CDJ66872.1 - 0.045 14.1 2.1 8.3 6.8 0.3 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc24 PF08286.11 CDJ66872.1 - 0.052 13.8 6.8 2.4 8.4 2.7 2.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.8 CDJ66872.1 - 0.079 13.0 6.2 0.34 10.9 0.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3138 PF11336.8 CDJ66872.1 - 0.14 10.8 7.1 0.2 10.3 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) GrpE PF01025.19 CDJ66872.1 - 0.21 11.2 5.2 1.2 8.8 1.5 2.1 2 0 0 2 2 2 0 GrpE CdvA PF18822.1 CDJ66872.1 - 0.25 11.2 4.7 1.1 9.1 0.4 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Fib_alpha PF08702.10 CDJ66872.1 - 0.31 11.2 3.9 0.9 9.7 0.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 CDJ66872.1 - 0.31 11.1 5.2 0.14 12.3 1.3 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 CDJ66872.1 - 0.34 10.9 4.8 0.25 11.4 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4618 PF15397.6 CDJ66872.1 - 0.35 10.3 6.3 0.88 8.9 6.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) KfrA_N PF11740.8 CDJ66872.1 - 0.48 11.1 15.4 0.15 12.7 2.0 3.0 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term DUF5320 PF17253.2 CDJ66872.1 - 1.2 10.3 4.6 8.8 7.5 0.2 2.5 2 1 1 3 3 2 0 Family of unknown function (DUF5320) CASP_C PF08172.12 CDJ66872.1 - 1.5 8.1 9.9 2.6 7.3 1.5 2.1 2 0 0 2 2 2 0 CASP C terminal DUF4140 PF13600.6 CDJ66872.1 - 1.7 9.1 11.1 2.1 8.8 1.2 2.8 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) AATF-Che1 PF13339.6 CDJ66872.1 - 1.8 9.2 8.1 4.8 7.9 2.8 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF4600 PF15372.6 CDJ66872.1 - 3.2 8.2 8.7 1.9 8.9 1.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Seryl_tRNA_N PF02403.22 CDJ66872.1 - 4.9 7.4 9.0 7.8 6.8 0.7 2.5 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain XhlA PF10779.9 CDJ66872.1 - 4.9 7.4 9.9 4.6 7.5 0.1 2.5 3 0 0 3 3 2 0 Haemolysin XhlA DivIC PF04977.15 CDJ66872.1 - 7.8 6.4 13.6 2.4 8.0 2.0 3.0 3 0 0 3 3 3 0 Septum formation initiator DUF2722 PF10846.8 CDJ66873.1 - 0.0014 17.7 1.9 0.0014 17.7 1.9 19.3 6 2 8 15 15 15 3 Protein of unknown function (DUF2722) FHIPEP PF00771.20 CDJ66874.1 - 0.98 7.8 7.6 1.5 7.2 7.6 1.2 1 0 0 1 1 1 0 FHIPEP family R_equi_Vir PF05526.11 CDJ66874.1 - 6.2 6.6 10.1 12 5.7 10.1 1.6 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Exonuc_VII_L PF02601.15 CDJ66875.1 - 0.00078 19.1 0.0 0.00078 19.1 0.0 3.8 5 2 0 5 5 5 1 Exonuclease VII, large subunit DUF2052 PF09747.9 CDJ66875.1 - 0.072 13.2 26.1 0.019 15.1 4.2 3.5 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) SID-1_RNA_chan PF13965.6 CDJ66875.1 - 0.76 8.1 4.1 17 3.7 0.0 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 EOS1 PF12326.8 CDJ66875.1 - 3.6 7.5 13.7 5 7.0 3.0 3.4 4 0 0 4 4 4 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ66875.1 - 5.2 5.9 36.4 0.052 12.5 10.4 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SAPS PF04499.15 CDJ66875.1 - 10 4.8 18.0 1.9 7.2 0.0 2.9 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein LRR_6 PF13516.6 CDJ66876.1 - 3.5e-12 45.3 13.9 0.12 12.5 0.0 10.1 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 CDJ66876.1 - 0.00026 21.3 16.8 0.081 13.4 0.3 5.5 3 3 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ66876.1 - 0.018 15.5 5.3 72 4.5 0.2 6.2 7 0 0 7 7 7 0 Leucine Rich Repeat Shadoo PF14999.6 CDJ66877.1 - 0.019 15.1 1.3 0.019 15.1 1.3 3.3 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective SRP54 PF00448.22 CDJ66878.1 - 2.6e-76 255.6 0.1 4.8e-76 254.8 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CDJ66878.1 - 2e-31 108.6 6.3 2.8e-31 108.0 1.5 2.6 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 CDJ66878.1 - 1.6e-13 50.6 0.2 1.7e-12 47.4 0.1 2.6 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 CDJ66878.1 - 1.3e-05 25.4 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CDJ66878.1 - 1.4e-05 24.7 0.2 9.4e-05 22.1 0.2 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CDJ66878.1 - 4.2e-05 24.0 0.7 0.00036 21.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CDJ66878.1 - 0.00012 21.9 1.6 0.00034 20.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 CDJ66878.1 - 0.00025 20.1 0.7 0.0024 16.9 0.0 2.7 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 CDJ66878.1 - 0.00028 21.3 0.0 0.0015 19.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain DRE2_N PF16803.5 CDJ66878.1 - 0.00076 19.7 0.1 0.09 13.0 0.0 2.5 2 0 0 2 2 2 1 Fe-S cluster assembly protein DRE2 N-terminus AAA_22 PF13401.6 CDJ66878.1 - 0.0022 18.3 0.4 0.02 15.2 0.1 2.8 2 2 1 3 3 3 1 AAA domain Zeta_toxin PF06414.12 CDJ66878.1 - 0.0044 16.3 0.1 0.0086 15.4 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.23 CDJ66878.1 - 0.0054 16.8 0.0 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 CDJ66878.1 - 0.0073 16.2 0.2 0.019 14.9 0.0 1.8 2 0 0 2 2 1 1 Adenylylsulphate kinase SRPRB PF09439.10 CDJ66878.1 - 0.0091 15.5 0.3 3.3 7.1 0.0 2.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF4310 PF14187.6 CDJ66878.1 - 0.011 15.4 0.2 0.019 14.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) ResIII PF04851.15 CDJ66878.1 - 0.013 15.5 0.7 0.079 13.0 0.7 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase PF06745.13 CDJ66878.1 - 0.022 14.1 0.0 0.069 12.5 0.0 1.9 1 0 0 1 1 1 0 KaiC Methyltransf_24 PF13578.6 CDJ66878.1 - 0.025 15.6 0.1 0.079 14.0 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain ATP_bind_1 PF03029.17 CDJ66878.1 - 0.036 13.8 0.2 0.15 11.8 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CDJ66878.1 - 0.037 14.1 0.5 0.3 11.2 0.2 2.5 2 1 0 2 2 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 CDJ66878.1 - 0.049 13.9 0.7 0.14 12.4 0.2 2.1 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 CDJ66878.1 - 0.049 13.5 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.17 CDJ66878.1 - 0.068 12.8 0.1 0.2 11.3 0.0 1.9 2 0 0 2 2 1 0 Thymidylate kinase DpnI_C PF17726.1 CDJ66878.1 - 0.074 13.2 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Dam-replacing HTH domain RNA_pol PF00940.19 CDJ66878.1 - 0.074 11.9 0.3 0.12 11.2 0.3 1.3 1 0 0 1 1 1 0 DNA-dependent RNA polymerase AAA_31 PF13614.6 CDJ66878.1 - 0.12 12.3 0.4 1.9 8.4 0.0 2.5 1 1 0 2 2 2 0 AAA domain IMUP PF15761.5 CDJ66878.1 - 0.26 12.0 9.3 0.65 10.7 9.3 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ66878.1 - 0.36 10.4 9.7 0.21 11.2 6.7 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ArsA_ATPase PF02374.15 CDJ66878.1 - 1.6 7.8 5.2 0.88 8.7 0.1 2.7 2 2 0 3 3 3 0 Anion-transporting ATPase Sec7_N PF12783.7 CDJ66879.1 - 0.12 12.2 1.7 0.23 11.3 1.5 1.7 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF572 PF04502.13 CDJ66879.1 - 0.24 11.0 17.7 0.34 10.5 17.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Brix PF04427.18 CDJ66881.1 - 5.7e-26 91.8 0.4 1.3e-25 90.7 0.4 1.5 1 1 0 1 1 1 1 Brix domain SR-25 PF10500.9 CDJ66881.1 - 0.0002 21.1 10.8 0.0002 21.1 10.8 5.5 5 2 0 5 5 5 3 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ66881.1 - 9.7 6.6 49.7 0.55 10.6 3.7 4.5 4 0 0 4 4 4 0 Early growth response N-terminal domain SepSecS PF05889.13 CDJ66883.1 - 0.036 12.8 0.1 0.054 12.2 0.1 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DDHD PF02862.17 CDJ66883.1 - 0.079 13.1 3.5 0.095 12.8 3.5 1.2 1 0 0 1 1 1 0 DDHD domain PSK_trans_fac PF07704.11 CDJ66883.1 - 0.11 13.3 1.2 0.22 12.3 0.0 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor Hid1 PF12722.7 CDJ66883.1 - 0.17 10.0 13.4 0.21 9.7 13.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spore_coat_CotO PF14153.6 CDJ66883.1 - 0.69 9.8 20.2 1 9.3 20.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.14 CDJ66883.1 - 1.1 7.5 11.9 1.4 7.1 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 CDJ66883.1 - 2.4 7.5 26.5 3.7 6.9 26.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIP PF07454.11 CDJ66883.1 - 3 7.2 11.8 4.4 6.7 11.8 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDJ66883.1 - 3.1 7.5 17.0 4.1 7.2 17.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ66883.1 - 3.7 6.4 12.5 5.5 5.8 12.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sec62 PF03839.16 CDJ66883.1 - 4.6 6.7 6.9 6.9 6.1 6.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 SAPS PF04499.15 CDJ66883.1 - 4.8 5.8 11.1 6.6 5.4 11.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paf1 PF03985.13 CDJ66883.1 - 5.5 5.9 19.7 7.2 5.5 19.7 1.2 1 0 0 1 1 1 0 Paf1 eIF2_C PF09173.11 CDJ66884.1 - 5.2e-29 100.3 0.3 5.8e-29 100.2 0.3 1.0 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal RskA PF10099.9 CDJ66885.1 - 0.00024 21.4 9.1 0.00024 21.4 9.1 2.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ66885.1 - 0.0022 17.7 9.3 0.0028 17.3 9.3 1.2 1 0 0 1 1 1 1 Spt20 family DUF4578 PF15147.6 CDJ66885.1 - 0.031 15.1 4.7 0.051 14.5 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) GDE_N PF12439.8 CDJ66885.1 - 0.058 12.8 0.6 0.07 12.5 0.6 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal TFIIA PF03153.13 CDJ66885.1 - 0.29 11.1 16.4 0.37 10.7 16.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ66885.1 - 0.54 9.1 7.0 0.66 8.8 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ66885.1 - 0.62 9.0 24.5 0.75 8.7 24.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ig_Tie2_1 PF10430.9 CDJ66885.1 - 3.5 8.1 5.4 1.1 9.8 2.2 1.8 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 Pep1_7 PF17232.2 CDJ66886.1 - 0.14 12.7 0.3 0.14 12.7 0.3 6.6 6 1 1 7 7 7 0 Elicitor peptide 1-7 CCSAP PF15748.5 CDJ66887.1 - 2 8.5 24.7 0.033 14.4 7.0 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated EPL1 PF10513.9 CDJ66887.1 - 4.6 7.6 16.2 5.7 7.3 3.3 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like SpoVR PF04293.13 CDJ66887.1 - 6.6 5.3 17.5 0.028 13.1 2.9 2.0 2 0 0 2 2 2 0 SpoVR like protein RRM_1 PF00076.22 CDJ66888.1 - 2.5e-17 62.4 0.0 5.9e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ66888.1 - 0.0065 16.4 0.0 0.036 14.1 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CDJ66888.1 - 0.029 14.0 0.0 0.71 9.5 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sin_N PF04801.13 CDJ66889.1 - 3.5e-104 349.4 39.5 4.4e-101 339.2 19.9 3.3 2 1 1 3 3 3 2 Sin-like protein conserved region RF-1 PF00472.20 CDJ66889.1 - 1.9e-10 40.7 7.0 1.9e-10 40.7 7.0 4.1 4 0 0 4 4 4 1 RF-1 domain PAP2 PF01569.21 CDJ66889.1 - 1.8 8.3 7.6 84 2.9 7.1 3.7 3 1 0 3 3 3 0 PAP2 superfamily XPG_N PF00752.17 CDJ66890.1 - 5.2e-12 46.1 0.6 1.2e-10 41.8 0.0 3.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 CDJ66890.1 - 8.4e-06 26.1 0.3 8.4e-06 26.1 0.3 4.3 5 1 0 5 5 5 1 XPG I-region RskA PF10099.9 CDJ66890.1 - 0.00014 22.2 0.4 0.00014 22.2 0.4 14.5 3 2 8 11 11 11 2 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ66890.1 - 0.0046 16.0 2.4 0.0046 16.0 2.4 12.9 6 3 3 9 9 9 3 Protein of unknown function (DUF2722) GREB1 PF15782.5 CDJ66891.1 - 1.3 6.1 45.2 1.8 5.5 45.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 CDJ66892.1 - 0.45 9.1 29.0 0.51 8.9 29.0 1.0 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 CDJ66892.1 - 0.5 9.0 28.0 0.61 8.7 28.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF572 PF04502.13 CDJ66892.1 - 1.3 8.5 33.2 1.7 8.2 33.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4551 PF15087.6 CDJ66892.1 - 2.1 7.1 26.9 2.6 6.8 26.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Draxin PF15550.6 CDJ66892.1 - 2.6 7.8 24.4 3.4 7.5 24.4 1.3 1 0 0 1 1 1 0 Draxin CDC27 PF09507.10 CDJ66892.1 - 4.2 6.6 37.9 5.7 6.2 37.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SR-25 PF10500.9 CDJ66893.1 - 0.00023 20.8 20.4 0.0005 19.8 11.3 7.1 4 2 1 5 5 5 2 Nuclear RNA-splicing-associated protein WD40 PF00400.32 CDJ66893.1 - 0.032 15.1 10.4 1.2 10.1 0.6 4.9 4 1 0 4 4 4 0 WD domain, G-beta repeat Otopetrin PF03189.13 CDJ66894.1 - 0.0013 17.7 0.0 0.044 12.6 0.0 2.6 2 1 0 2 2 2 1 Otopetrin DUF2722 PF10846.8 CDJ66894.1 - 0.0013 17.8 11.2 0.0013 17.8 11.2 4.7 3 1 1 4 4 4 1 Protein of unknown function (DUF2722) DUF4171 PF13775.6 CDJ66894.1 - 0.0017 18.8 10.0 0.0017 18.8 10.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4171) RskA PF10099.9 CDJ66894.1 - 0.0021 18.4 0.0 0.0021 18.4 0.0 8.1 2 2 4 6 6 6 1 Anti-sigma-K factor rskA Gti1_Pac2 PF09729.9 CDJ66894.1 - 5 7.2 25.4 2.6 8.1 0.1 3.6 3 0 0 3 3 3 0 Gti1/Pac2 family RskA PF10099.9 CDJ66895.1 - 0.00023 21.5 3.0 0.00023 21.5 3.0 7.0 1 1 3 6 6 6 1 Anti-sigma-K factor rskA DUF2076 PF09849.9 CDJ66895.1 - 0.0035 17.4 26.7 0.0035 17.4 26.7 6.0 2 2 3 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2076) ANAPC_CDC26 PF10471.9 CDJ66895.1 - 0.02 15.7 7.7 0.02 15.7 7.7 7.9 2 1 3 5 5 5 0 Anaphase-promoting complex APC subunit CDC26 DUF359 PF04019.12 CDJ66895.1 - 0.074 12.7 0.0 0.074 12.7 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF359) SOUL PF04832.12 CDJ66896.1 - 6.4e-31 107.8 0.1 2.1e-29 102.9 0.1 2.2 1 1 0 1 1 1 1 SOUL heme-binding protein DUF4667 PF15700.5 CDJ66896.1 - 0.0099 16.0 4.6 0.0099 16.0 4.6 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ66896.1 - 0.023 14.3 11.9 0.023 14.3 11.9 2.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ66896.1 - 1.2 7.8 7.1 1.6 7.4 7.1 1.2 1 0 0 1 1 1 0 Presenilin BRF1 PF07741.13 CDJ66896.1 - 2.3 8.6 10.3 9.7 6.6 9.7 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain RskA PF10099.9 CDJ66897.1 - 0.001 19.4 12.8 0.001 19.4 12.8 2.5 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ66897.1 - 0.024 13.6 43.0 0.11 11.4 7.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ66897.1 - 0.043 13.4 47.8 0.15 11.7 10.6 2.2 2 0 0 2 2 2 0 Spt20 family EIIBC-GUT_N PF03612.14 CDJ66897.1 - 0.045 13.5 10.1 0.22 11.3 0.1 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Med3 PF11593.8 CDJ66897.1 - 0.075 12.2 42.1 0.017 14.3 22.3 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal 53-BP1_Tudor PF09038.10 CDJ66897.1 - 0.083 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor DUF4834 PF16118.5 CDJ66897.1 - 0.16 12.9 21.3 2.2 9.3 11.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RNA_pol_Rbc25 PF08292.12 CDJ66897.1 - 0.43 10.8 7.0 5.7 7.2 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 PBP_sp32 PF07222.12 CDJ66897.1 - 0.6 9.5 17.1 0.041 13.3 7.7 2.2 2 0 0 2 2 2 0 Proacrosin binding protein sp32 eIF-3_zeta PF05091.12 CDJ66897.1 - 0.72 8.8 21.7 0.58 9.1 10.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2076 PF09849.9 CDJ66897.1 - 0.75 9.8 32.9 0.99 9.4 19.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TCP PF03634.13 CDJ66897.1 - 0.89 10.1 26.5 0.51 10.9 16.0 2.2 2 0 0 2 2 2 0 TCP family transcription factor Roughex PF06020.11 CDJ66897.1 - 0.92 8.5 17.5 1.9 7.5 7.5 2.1 2 0 0 2 2 2 0 Drosophila roughex protein Thg1C PF14413.6 CDJ66897.1 - 1.1 9.4 10.4 2.8 8.1 3.1 2.5 2 1 0 2 2 2 0 Thg1 C terminal domain FCP1_C PF09309.10 CDJ66897.1 - 2.6 7.9 24.0 0.77 9.6 12.6 2.2 2 0 0 2 2 2 0 FCP1, C-terminal Ctr PF04145.15 CDJ66897.1 - 3.1 8.4 10.7 7.2 7.2 0.5 2.3 2 0 0 2 2 2 0 Ctr copper transporter family WBP-1 PF11669.8 CDJ66897.1 - 3.2 8.5 9.2 3.1 8.5 0.4 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 Hydin_ADK PF17213.3 CDJ66897.1 - 4.3 7.6 21.9 5.5 7.2 0.8 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain FHIPEP PF00771.20 CDJ66897.1 - 5.1 5.4 7.9 4.2 5.7 1.7 2.1 2 0 0 2 2 2 0 FHIPEP family RR_TM4-6 PF06459.12 CDJ66897.1 - 6.4 6.5 16.8 1.7 8.4 8.4 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EOS1 PF12326.8 CDJ66897.1 - 8.2 6.3 9.1 6.1 6.7 2.9 2.3 2 0 0 2 2 2 0 N-glycosylation protein XAP5 PF04921.14 CDJ66897.1 - 9.4 6.0 19.4 0.98 9.2 10.3 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator Pkinase PF00069.25 CDJ66898.1 - 1.9e-38 132.3 0.3 9e-24 84.2 0.0 5.2 2 1 3 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ66898.1 - 6e-15 55.2 10.4 1.6e-08 34.1 4.4 3.6 3 1 0 3 3 3 2 Protein tyrosine kinase TFIIA PF03153.13 CDJ66898.1 - 0.00016 21.8 30.4 0.00016 21.8 30.4 3.5 3 1 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Otopetrin PF03189.13 CDJ66898.1 - 0.0014 17.6 0.0 0.039 12.8 0.0 2.7 2 2 0 2 2 2 1 Otopetrin RskA PF10099.9 CDJ66898.1 - 0.061 13.6 0.0 0.061 13.6 0.0 6.9 3 3 2 5 5 5 0 Anti-sigma-K factor rskA Afi1 PF07792.12 CDJ66898.1 - 0.16 12.4 0.1 0.16 12.4 0.1 4.7 3 2 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Chromo PF00385.24 CDJ66900.1 - 2.2e-14 53.1 0.0 2.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AP2 PF00847.20 CDJ66901.1 - 1.5e-15 57.1 4.6 3.4e-12 46.4 0.1 2.5 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.6 CDJ66901.1 - 1.3e-05 25.4 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AP2-coincident C-terminal Got1 PF04178.12 CDJ66902.1 - 5e-30 104.2 10.0 6.8e-30 103.8 10.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Ribosomal_L34e PF01199.18 CDJ66903.1 - 4.1e-35 120.0 5.1 4.1e-35 120.0 5.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L34e zf-3CxxC_2 PF17180.4 CDJ66903.1 - 0.046 14.5 2.1 0.046 14.5 2.1 1.9 2 0 0 2 2 2 0 Zinc-binding domain FtsJ PF01728.19 CDJ66904.1 - 1e-53 182.1 0.0 1.3e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CDJ66904.1 - 0.00072 19.4 0.0 0.0023 17.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ66904.1 - 0.0009 19.9 0.0 0.0018 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NSP16 PF06460.12 CDJ66904.1 - 0.0073 15.4 0.0 0.0085 15.2 0.0 1.2 1 0 0 1 1 1 1 Coronavirus NSP16 Methyltransf_23 PF13489.6 CDJ66904.1 - 0.025 14.4 0.0 0.083 12.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ66904.1 - 0.14 12.8 0.0 0.63 10.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain HJURP_C PF12347.8 CDJ66905.1 - 0.079 13.0 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat NUDIX_2 PF13869.6 CDJ66906.1 - 1.3e-54 184.6 0.0 1.6e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase DUF667 PF05018.13 CDJ66907.1 - 1.4e-13 51.0 0.2 1.7e-13 50.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) HSDR_N_2 PF13588.6 CDJ66907.1 - 0.046 13.7 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) GvpK PF05121.12 CDJ66908.1 - 0.15 12.1 0.5 0.3 11.2 0.5 1.4 1 0 0 1 1 1 0 Gas vesicle protein K RskA PF10099.9 CDJ66910.1 - 2.1e-05 24.9 13.2 0.00088 19.6 1.4 2.1 2 0 0 2 2 2 2 Anti-sigma-K factor rskA Kelch_4 PF13418.6 CDJ66910.1 - 0.072 13.1 0.1 0.37 10.8 0.1 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain Ribosomal_60s PF00428.19 CDJ66910.1 - 0.43 11.2 22.9 2 9.1 8.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1995 PF09353.10 CDJ66910.1 - 0.48 10.4 2.7 2.1 8.3 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1995) Kelch_1 PF01344.25 CDJ66910.1 - 0.55 9.9 0.1 0.55 9.9 0.1 2.1 2 0 0 2 2 2 0 Kelch motif Adeno_PIX PF03955.14 CDJ66910.1 - 3.2 8.0 15.5 1.3 9.2 2.6 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Shadoo PF14999.6 CDJ66910.1 - 3.7 7.7 17.5 5 7.2 2.8 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF3138 PF11336.8 CDJ66910.1 - 5.4 5.5 9.5 2.1 6.8 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Peptidase_M22 PF00814.25 CDJ66911.1 - 1.3e-77 261.2 0.5 2e-57 195.0 0.8 2.1 1 1 1 2 2 2 2 Glycoprotease family ATP-synt_C PF00137.21 CDJ66912.1 - 9.4e-31 106.0 32.3 4.9e-19 68.4 13.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.13 CDJ66912.1 - 4.4 5.7 6.8 11 4.4 0.6 2.4 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Mtc PF03820.17 CDJ66913.1 - 3.4e-64 216.8 0.6 7.4e-53 179.6 0.4 2.0 1 1 1 2 2 2 2 Tricarboxylate carrier Activator_LAG-3 PF11498.8 CDJ66914.1 - 0.34 9.8 13.7 0.42 9.5 13.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Surface_antigen PF11054.8 CDJ66915.1 - 5e-25 88.6 2.7 9.6e-21 74.6 0.8 2.1 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen Sod_Fe_N PF00081.22 CDJ66916.1 - 1.3e-23 83.3 0.3 1.4e-23 83.2 0.3 1.0 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain TAL_FSA PF00923.19 CDJ66917.1 - 6.5e-10 38.8 0.2 9e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase KNOX2 PF03791.13 CDJ66917.1 - 0.17 11.4 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 KNOX2 domain Ribosomal_60s PF00428.19 CDJ66917.1 - 1.6 9.4 20.0 0.078 13.6 10.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein SR-25 PF10500.9 CDJ66917.1 - 5.3 6.6 15.1 1.1 8.8 11.2 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Adaptin_N PF01602.20 CDJ66918.1 - 4.2e-39 134.5 5.9 5.1e-39 134.2 5.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDJ66918.1 - 3.4e-10 40.2 1.1 7.2e-10 39.1 0.4 1.9 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDJ66918.1 - 2.3e-05 24.3 1.9 0.71 10.3 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat RTP1_C1 PF10363.9 CDJ66918.1 - 0.00011 22.4 0.3 0.016 15.4 0.0 2.9 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 CDJ66918.1 - 0.00014 22.2 0.1 0.00014 22.2 0.1 3.4 1 1 2 3 3 3 1 HEAT repeats Rpn3_C PF08375.11 CDJ66918.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal SUIM_assoc PF16619.5 CDJ66918.1 - 0.06 13.4 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 HEAT_PBS PF03130.16 CDJ66918.1 - 0.25 12.1 0.1 0.25 12.1 0.1 4.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 CDJ66918.1 - 2.6 8.6 13.9 18 6.0 0.0 5.7 5 1 1 6 6 6 0 HEAT-like repeat Pro_isomerase PF00160.21 CDJ66920.1 - 1.6e-06 28.5 0.0 2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CW_binding_2 PF04122.12 CDJ66920.1 - 0.1 13.3 0.3 0.13 12.9 0.3 1.5 1 1 0 1 1 1 0 Putative cell wall binding repeat 2 PI-PLC-X PF00388.19 CDJ66922.1 - 2.6e-32 111.4 0.0 4.1e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_6 PF13405.6 CDJ66922.1 - 0.088 12.8 0.6 0.29 11.2 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain Seryl_tRNA_N PF02403.22 CDJ66923.1 - 0.16 12.2 15.6 0.025 14.8 8.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FUSC PF04632.12 CDJ66923.1 - 0.42 9.1 13.7 0.48 8.9 13.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Med30 PF11315.8 CDJ66923.1 - 0.98 9.6 8.1 2 8.6 8.1 1.6 1 1 0 1 1 1 0 Mediator complex subunit 30 Mod_r PF07200.13 CDJ66923.1 - 8.4 6.5 17.6 7.2 6.7 16.3 1.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CAMSAP_CC1 PF17095.5 CDJ66924.1 - 0.027 14.3 4.1 0.027 14.3 4.1 3.0 3 0 0 3 3 3 0 Spectrin-binding region of Ca2+-Calmodulin SNF2_N PF00176.23 CDJ66928.1 - 1.4e-37 129.2 0.0 1.1e-30 106.6 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ66928.1 - 1.5e-10 41.4 0.1 6.5e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 CDJ66928.1 - 1.8e-07 31.0 5.2 1.8e-07 31.0 5.2 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ66928.1 - 3.4e-05 24.1 11.5 3.4e-05 24.1 11.5 4.2 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ66928.1 - 0.00068 19.5 11.1 0.0008 19.2 6.3 3.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ66928.1 - 0.001 19.2 6.6 0.001 19.2 6.6 3.6 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CDJ66928.1 - 0.0025 17.7 14.7 0.032 14.1 14.7 3.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ66928.1 - 0.0029 17.5 15.9 0.0029 17.5 15.9 3.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ66928.1 - 0.0047 16.7 6.5 0.0047 16.7 6.5 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CDJ66928.1 - 0.6 10.0 7.3 5.3 6.9 7.4 2.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain AP2 PF00847.20 CDJ66929.1 - 9.8e-10 38.5 3.7 2.5e-05 24.4 0.7 4.5 6 0 0 6 6 6 2 AP2 domain CCB1 PF12046.8 CDJ66930.1 - 0.098 12.0 0.1 0.11 11.8 0.1 1.0 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B 4PPT_N PF17837.1 CDJ66930.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Pro_isomerase PF00160.21 CDJ66931.1 - 2.9e-31 108.9 0.0 1.5e-30 106.5 0.0 2.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.9 CDJ66931.1 - 0.0064 16.1 12.7 0.0064 16.1 12.7 2.5 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein DUF2408 PF10303.9 CDJ66931.1 - 0.28 11.8 4.3 0.71 10.4 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) RSRP PF17069.5 CDJ66931.1 - 0.65 9.5 36.2 0.039 13.5 18.3 2.4 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 Lin-8 PF03353.15 CDJ66931.1 - 3.3 7.2 15.4 0.59 9.6 3.2 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist KH_1 PF00013.29 CDJ66933.1 - 1.5e-17 63.1 0.0 5.9e-08 32.4 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 CDJ66933.1 - 2.9e-06 27.1 1.0 0.063 13.2 0.0 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CDJ66933.1 - 0.00013 21.7 0.1 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 KH domain SUIM_assoc PF16619.5 CDJ66933.1 - 0.011 15.7 27.6 0.06 13.4 0.5 4.2 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ66933.1 - 0.92 9.8 50.9 0.034 14.4 2.5 3.8 3 1 1 4 4 4 0 Anti-sigma-K factor rskA Peptidase_S64 PF08192.11 CDJ66933.1 - 3.9 5.8 8.3 6.1 5.2 8.3 1.3 1 0 0 1 1 1 0 Peptidase family S64 Spt20 PF12090.8 CDJ66933.1 - 9.3 5.8 24.4 0.75 9.4 10.0 3.0 3 0 0 3 3 3 0 Spt20 family Retrotrans_gag PF03732.17 CDJ66935.1 - 0.0081 16.4 0.3 0.039 14.2 0.1 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein Phe_ZIP PF08916.11 CDJ66935.1 - 0.074 13.8 0.4 12 6.7 0.0 3.2 3 0 0 3 3 3 0 Phenylalanine zipper Asp_protease_2 PF13650.6 CDJ66936.1 - 1.6e-09 38.3 0.0 3.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ66936.1 - 1.7e-09 38.1 0.0 4e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ66936.1 - 5e-09 36.0 0.0 1.2e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 Retroviral aspartyl protease RVT_1 PF00078.27 CDJ66936.1 - 8.5e-06 25.4 0.0 3.4e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 CDJ66936.1 - 8.2e-05 22.4 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ66936.1 - 0.011 16.0 0.0 0.029 14.7 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Histone PF00125.24 CDJ66937.1 - 2.6e-15 56.9 0.0 3.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 CDJ66937.1 - 0.00023 21.6 0.0 0.00037 20.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 CDJ66937.1 - 0.00099 19.4 0.1 0.0018 18.5 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SID-1_RNA_chan PF13965.6 CDJ66939.1 - 0.59 8.5 7.2 0.15 10.5 1.0 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 SR-25 PF10500.9 CDJ66940.1 - 0.001 18.7 7.9 0.001 18.7 7.9 2.8 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF1645 PF07816.11 CDJ66941.1 - 0.00059 20.5 6.1 0.00085 19.9 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ66941.1 - 0.095 12.3 2.5 0.12 12.0 2.5 1.1 1 0 0 1 1 1 0 Spt20 family IMUP PF15761.5 CDJ66941.1 - 0.14 12.8 8.0 0.24 12.1 8.0 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF3446 PF11928.8 CDJ66941.1 - 0.23 11.8 10.9 0.34 11.3 10.9 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain GREB1 PF15782.5 CDJ66941.1 - 0.31 8.1 2.1 0.35 7.9 2.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RAP1 PF07218.11 CDJ66941.1 - 0.35 9.1 1.0 0.39 8.9 1.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.13 CDJ66941.1 - 0.47 8.5 8.1 0.63 8.1 8.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Lin-8 PF03353.15 CDJ66941.1 - 0.56 9.7 2.5 0.75 9.3 2.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ66941.1 - 0.69 9.9 5.0 0.85 9.5 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_pp85 PF04637.12 CDJ66941.1 - 6.4 5.1 5.2 8 4.8 5.2 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Ribosomal_L1 PF00687.21 CDJ66942.1 - 2.3e-10 40.6 0.0 2.9e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MAT1 PF06391.13 CDJ66943.1 - 2e-11 44.1 7.2 2e-11 44.1 7.2 2.2 2 0 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.6 CDJ66943.1 - 9.4e-05 22.3 11.1 0.00021 21.2 11.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain SSP160 PF06933.11 CDJ66943.1 - 0.009 14.3 9.5 0.011 14.0 9.5 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 zf-C3HC4_5 PF17121.5 CDJ66943.1 - 0.023 14.6 5.5 0.023 14.6 5.5 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ66943.1 - 0.049 13.5 9.4 0.21 11.5 9.4 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 CDJ66943.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.9 4 0 0 4 4 3 0 Rad50 zinc hook motif zf-C3HC4 PF00097.25 CDJ66943.1 - 0.15 12.0 10.0 0.47 10.4 10.0 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ66943.1 - 0.16 12.3 11.9 2 8.8 13.0 2.2 1 1 1 2 2 2 0 Ring finger domain Histidinol_dh PF00815.20 CDJ66943.1 - 0.19 10.7 1.8 0.32 10.0 1.8 1.3 1 0 0 1 1 1 0 Histidinol dehydrogenase zf-RING_UBOX PF13445.6 CDJ66943.1 - 0.4 10.8 9.8 2.1 8.4 6.3 2.8 2 0 0 2 2 2 0 RING-type zinc-finger PAP1 PF08601.10 CDJ66943.1 - 0.6 9.8 14.6 0.83 9.3 14.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 BatA PF07584.11 CDJ66943.1 - 1 9.8 13.5 3.3 8.2 13.5 1.9 1 1 0 1 1 1 0 Aerotolerance regulator N-terminal 2TM PF13239.6 CDJ66943.1 - 2 8.8 9.0 4.8 7.6 9.0 1.7 1 0 0 1 1 1 0 2TM domain Lin-8 PF03353.15 CDJ66943.1 - 2.6 7.5 15.7 0.23 11.0 10.9 1.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist KdpC PF02669.15 CDJ66943.1 - 4.5 7.1 9.7 3.1 7.6 4.6 2.6 2 1 0 2 2 2 0 K+-transporting ATPase, c chain zf-C3HC4_2 PF13923.6 CDJ66943.1 - 6.8 6.6 11.1 58 3.6 0.0 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RskA PF10099.9 CDJ66945.1 - 0.0033 17.8 17.7 0.0033 17.8 17.7 10.1 4 3 2 6 6 6 3 Anti-sigma-K factor rskA AI-2E_transport PF01594.16 CDJ66946.1 - 0.0016 17.7 0.0 0.0017 17.6 0.0 1.0 1 0 0 1 1 1 1 AI-2E family transporter Amnionless PF14828.6 CDJ66946.1 - 0.0016 17.3 0.1 0.0018 17.2 0.1 1.1 1 0 0 1 1 1 1 Amnionless Tmemb_9 PF05434.11 CDJ66946.1 - 0.0058 16.5 0.1 0.0058 16.5 0.1 2.1 1 1 1 2 2 2 1 TMEM9 zf-LITAF-like PF10601.9 CDJ66946.1 - 0.0092 16.2 0.1 0.41 10.9 0.0 2.1 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain DUF5527 PF17665.1 CDJ66946.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Orf78 PF06024.12 CDJ66946.1 - 0.027 14.8 0.1 0.077 13.3 0.0 1.7 1 1 1 2 2 2 0 Orf78 (ac78) E7 PF00527.18 CDJ66946.1 - 0.028 14.6 0.1 0.047 13.9 0.1 1.3 1 0 0 1 1 1 0 E7 protein, Early protein DUF4199 PF13858.6 CDJ66946.1 - 0.15 12.4 0.1 0.19 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) SSP160 PF06933.11 CDJ66946.1 - 6 4.9 10.4 7.8 4.6 10.4 1.3 1 1 0 1 1 1 0 Special lobe-specific silk protein SSP160 F-protein PF00469.20 CDJ66946.1 - 6.2 6.3 5.7 0.4 10.2 0.3 1.6 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Androgen_recep PF02166.16 CDJ66947.1 - 8.3 5.1 10.0 7.4 5.3 10.0 1.0 1 0 0 1 1 1 0 Androgen receptor Apt1 PF10351.9 CDJ66948.1 - 0.00025 20.1 3.4 0.00034 19.6 3.4 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain Ctr PF04145.15 CDJ66948.1 - 0.0011 19.6 0.4 0.25 11.9 0.0 2.4 2 0 0 2 2 2 1 Ctr copper transporter family SPX PF03105.19 CDJ66948.1 - 0.0028 17.6 4.8 0.0042 17.1 4.8 1.2 1 0 0 1 1 1 1 SPX domain SR-25 PF10500.9 CDJ66948.1 - 0.015 15.0 37.3 0.036 13.7 16.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 CDJ66948.1 - 0.017 15.1 19.5 0.16 11.9 11.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DUF4667 PF15700.5 CDJ66948.1 - 0.017 15.2 20.6 0.1 12.7 2.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) DUF4598 PF15370.6 CDJ66948.1 - 0.048 14.1 1.9 2.4 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) Spt20 PF12090.8 CDJ66948.1 - 0.052 13.2 1.8 0.09 12.4 1.8 1.4 1 0 0 1 1 1 0 Spt20 family DUF4158 PF13700.6 CDJ66948.1 - 0.46 10.3 0.1 0.46 10.3 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4158) Peptidase_S64 PF08192.11 CDJ66948.1 - 0.74 8.2 7.5 1 7.8 7.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Pap_E4 PF02711.14 CDJ66948.1 - 0.77 10.8 8.1 6.4 7.8 0.2 2.5 2 0 0 2 2 2 0 E4 protein DUF1635 PF07795.11 CDJ66948.1 - 3.3 7.5 13.2 0.98 9.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) PMSR PF01625.21 CDJ66949.1 - 5.3e-50 169.6 0.0 6.5e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase TraD_N PF12615.8 CDJ66950.1 - 3.4 8.5 7.6 0.93 10.3 0.8 2.7 2 0 0 2 2 2 0 F sex factor protein N terminal DUF2722 PF10846.8 CDJ66951.1 - 0.0059 15.6 1.0 0.0059 15.6 1.0 3.0 2 1 0 3 3 3 1 Protein of unknown function (DUF2722) SARAF PF06682.12 CDJ66951.1 - 0.46 10.1 15.3 0.059 13.0 1.2 2.3 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3464 PF11947.8 CDJ66951.1 - 0.57 9.9 18.2 13 5.5 0.0 3.4 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 Ndc1_Nup PF09531.10 CDJ66951.1 - 1.6 7.3 15.0 2.7 6.5 15.0 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Allexi_40kDa PF05549.11 CDJ66952.1 - 0.0028 17.2 6.4 0.0038 16.8 6.4 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein DUF4718 PF15842.5 CDJ66952.1 - 0.032 14.0 2.4 0.068 13.0 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Sporozoite_P67 PF05642.11 CDJ66952.1 - 0.084 11.0 6.6 0.1 10.7 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PP2C_C PF07830.13 CDJ66952.1 - 0.24 11.9 2.0 2.1 8.9 0.5 2.2 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain GREB1 PF15782.5 CDJ66952.1 - 0.26 8.4 10.9 0.27 8.3 10.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 CDJ66952.1 - 0.33 10.5 35.0 0.066 12.8 22.9 2.3 2 0 0 2 2 2 0 Spt20 family MDM10 PF12519.8 CDJ66952.1 - 0.99 8.2 6.3 1.4 7.7 6.3 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 AAA_23 PF13476.6 CDJ66952.1 - 2.9 8.4 13.1 3.4 8.1 8.8 2.0 2 0 0 2 2 2 0 AAA domain SLC12 PF03522.15 CDJ66952.1 - 9.5 5.1 12.0 13 4.7 12.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RskA PF10099.9 CDJ66953.1 - 1.1e-06 29.1 1.0 1.1e-06 29.1 1.0 2.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ66953.1 - 0.0019 17.9 22.2 0.0019 17.9 22.2 2.0 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.11 CDJ66953.1 - 0.22 10.0 26.7 0.27 9.7 26.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4050 PF13259.6 CDJ66953.1 - 9.6 6.5 30.4 10 6.4 6.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) DUF4045 PF13254.6 CDJ66953.1 - 9.8 5.7 35.1 5.6 6.5 8.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF4614 PF15391.6 CDJ66956.1 - 3.7 7.5 23.7 2.4 8.1 11.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Ribosomal_L28e PF01778.17 CDJ66957.1 - 1.4e-19 70.9 0.3 1.7e-19 70.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family rve PF00665.26 CDJ66959.1 - 1.4e-13 51.0 0.0 4e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ66959.1 - 9.7e-11 41.6 5.0 2.3e-10 40.4 5.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 CDJ66959.1 - 5.3e-10 39.1 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 CDJ66959.1 - 0.0027 17.4 0.1 0.028 14.2 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ66959.1 - 0.075 13.3 0.4 0.18 12.1 0.4 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Helicase_RecD PF05127.14 CDJ66960.1 - 0.18 11.6 2.3 0.28 11.0 2.3 1.3 1 0 0 1 1 1 0 Helicase IHABP4_N PF16174.5 CDJ66960.1 - 0.2 12.3 23.3 0.29 11.7 23.3 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Presenilin PF01080.17 CDJ66960.1 - 0.41 9.4 14.3 0.5 9.1 14.3 1.1 1 0 0 1 1 1 0 Presenilin Gti1_Pac2 PF09729.9 CDJ66960.1 - 0.76 9.8 9.7 1 9.4 9.7 1.3 1 1 0 1 1 1 0 Gti1/Pac2 family LPP20 PF02169.16 CDJ66960.1 - 1.1 9.7 15.6 0.055 13.8 9.0 1.9 2 0 0 2 2 2 0 LPP20 lipoprotein SLC12 PF03522.15 CDJ66960.1 - 2.4 7.1 7.7 2.9 6.8 7.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF4834 PF16118.5 CDJ66960.1 - 3.4 8.7 16.7 1.6 9.7 8.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4551 PF15087.6 CDJ66960.1 - 3.7 6.3 13.8 4.2 6.1 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Coilin_N PF15862.5 CDJ66960.1 - 3.9 7.3 17.5 3.4 7.5 12.4 2.1 2 0 0 2 2 2 0 Coilin N-terminus EphA2_TM PF14575.6 CDJ66960.1 - 5 8.1 5.4 5.2 8.0 1.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Hid1 PF12722.7 CDJ66960.1 - 9.3 4.2 10.7 11 4.0 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spt20 PF12090.8 CDJ66961.1 - 0.0024 17.5 16.3 0.0024 17.5 16.3 1.1 1 0 0 1 1 1 1 Spt20 family baeRF_family10 PF18854.1 CDJ66961.1 - 0.0044 17.3 7.0 0.0055 17.0 7.0 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF2722 PF10846.8 CDJ66961.1 - 0.021 13.8 14.6 0.026 13.5 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Bul1_N PF04425.12 CDJ66961.1 - 0.024 13.4 2.3 0.027 13.3 2.3 1.1 1 0 0 1 1 1 0 Bul1 N terminus Roughex PF06020.11 CDJ66961.1 - 0.053 12.6 8.5 0.055 12.6 8.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Phostensin PF13914.6 CDJ66961.1 - 0.067 13.8 9.1 0.095 13.3 9.1 1.4 1 1 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region TERB2 PF15101.6 CDJ66961.1 - 0.1 12.7 11.0 0.12 12.4 11.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NAD_kinase PF01513.21 CDJ66961.1 - 0.12 11.5 0.8 0.14 11.3 0.8 1.1 1 0 0 1 1 1 0 ATP-NAD kinase CNDH2_M PF16869.5 CDJ66961.1 - 0.13 12.9 4.5 0.17 12.5 4.5 1.3 1 0 0 1 1 1 0 PF16858 TFIIA PF03153.13 CDJ66961.1 - 0.17 11.8 19.5 0.19 11.7 19.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLN3 PF02487.17 CDJ66961.1 - 0.22 10.5 4.6 0.25 10.4 4.6 1.1 1 0 0 1 1 1 0 CLN3 protein Peptidase_S30 PF01577.16 CDJ66961.1 - 0.4 10.3 8.5 0.43 10.1 8.5 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease Mitofilin PF09731.9 CDJ66961.1 - 0.42 9.4 17.0 0.45 9.3 17.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein EPL1 PF10513.9 CDJ66961.1 - 0.61 10.4 7.0 0.64 10.4 7.0 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like CCDC53 PF10152.9 CDJ66961.1 - 0.71 10.3 10.2 0.84 10.0 10.2 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FAM199X PF15814.5 CDJ66961.1 - 1.1 8.3 5.4 1.4 7.9 5.4 1.1 1 0 0 1 1 1 0 Protein family FAM199X Hid1 PF12722.7 CDJ66961.1 - 1.2 7.1 6.7 1.3 7.0 6.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.17 CDJ66961.1 - 1.3 9.2 7.5 1.4 9.0 7.5 1.1 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 CDJ66961.1 - 1.5 8.8 6.1 1.6 8.7 6.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ66961.1 - 1.7 7.4 7.2 1.9 7.3 7.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter HGTP_anticodon2 PF12745.7 CDJ66961.1 - 1.7 8.1 9.9 2 7.8 9.9 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs CPSF100_C PF13299.6 CDJ66961.1 - 1.8 8.7 8.5 2 8.6 8.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF1980 PF09323.10 CDJ66961.1 - 2.4 8.1 5.5 3.1 7.7 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 CDJ66961.1 - 2.9 6.6 10.7 3.1 6.5 10.7 1.1 1 0 0 1 1 1 0 Presenilin XRN_M PF17846.1 CDJ66961.1 - 5.1 5.9 8.7 5.7 5.8 8.7 1.0 1 0 0 1 1 1 0 Xrn1 helical domain SUIM_assoc PF16619.5 CDJ66961.1 - 5.5 7.1 29.9 2.2 8.4 14.6 2.4 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HAT PF02184.16 CDJ66962.1 - 0.034 14.1 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat Ribosomal_60s PF00428.19 CDJ66963.1 - 0.34 11.5 7.0 0.53 10.9 7.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein RecT PF03837.14 CDJ66967.1 - 2.4 7.6 6.8 0.35 10.3 1.0 2.6 3 0 0 3 3 3 0 RecT family HECT PF00632.25 CDJ66969.1 - 1.3e-51 175.9 0.0 2.4e-51 175.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) KI67R PF08065.12 CDJ66969.1 - 1.3 9.6 18.5 0.91 10.1 0.1 3.7 2 0 0 2 2 2 0 KI67R (NUC007) repeat GILT PF03227.16 CDJ66970.1 - 1.5e-22 79.9 0.2 1.5e-22 79.9 0.2 1.9 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) XAP5 PF04921.14 CDJ66973.1 - 5.4e-28 98.5 1.0 6.1e-28 98.3 1.0 1.0 1 0 0 1 1 1 1 XAP5, circadian clock regulator DDRGK PF09756.9 CDJ66974.1 - 0.01 15.5 15.4 0.01 15.5 15.4 1.1 1 0 0 1 1 1 0 DDRGK domain eIF3_subunit PF08597.10 CDJ66974.1 - 0.023 14.6 19.9 0.024 14.6 19.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TFIIA PF03153.13 CDJ66974.1 - 0.027 14.5 45.0 0.03 14.3 45.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ADP_ribosyl_GH PF03747.14 CDJ66974.1 - 0.056 13.2 3.3 0.06 13.1 3.3 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Cwf_Cwc_15 PF04889.12 CDJ66974.1 - 0.063 13.0 20.3 0.071 12.8 20.3 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SpoIIP PF07454.11 CDJ66974.1 - 0.14 11.6 17.1 0.17 11.3 17.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) HemX PF04375.14 CDJ66974.1 - 0.25 10.6 33.1 0.29 10.4 33.1 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Connexin PF00029.19 CDJ66974.1 - 0.28 10.9 11.8 0.31 10.8 11.8 1.2 1 0 0 1 1 1 0 Connexin Plasmodium_Vir PF05795.11 CDJ66974.1 - 0.3 10.5 19.0 0.34 10.3 19.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Miga PF10265.9 CDJ66974.1 - 0.36 9.7 25.7 0.45 9.4 25.7 1.0 1 0 0 1 1 1 0 Mitoguardin eIF-3_zeta PF05091.12 CDJ66974.1 - 0.37 9.7 24.2 0.38 9.7 24.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PNISR PF15996.5 CDJ66974.1 - 0.39 11.0 25.6 0.47 10.7 25.6 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR FAM76 PF16046.5 CDJ66974.1 - 0.41 10.0 25.1 0.49 9.7 25.1 1.0 1 0 0 1 1 1 0 FAM76 protein NST1 PF13945.6 CDJ66974.1 - 0.44 10.6 32.2 0.56 10.3 32.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Lin-8 PF03353.15 CDJ66974.1 - 0.47 10.0 27.3 0.55 9.7 27.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RPN2_C PF18004.1 CDJ66974.1 - 0.52 10.2 17.5 0.6 10.0 17.5 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Macoilin PF09726.9 CDJ66974.1 - 0.53 8.8 29.5 0.73 8.3 29.5 1.2 1 0 0 1 1 1 0 Macoilin family Tim54 PF11711.8 CDJ66974.1 - 0.7 8.6 15.1 0.78 8.5 15.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2681 PF10883.8 CDJ66974.1 - 1 9.8 28.0 2.1 8.8 28.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Sec62 PF03839.16 CDJ66974.1 - 1.1 8.8 12.1 1.2 8.6 12.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 ALMT PF11744.8 CDJ66974.1 - 1.1 8.0 19.6 1.3 7.8 19.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4746 PF15928.5 CDJ66974.1 - 1.1 8.6 10.0 1.1 8.6 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FHIPEP PF00771.20 CDJ66974.1 - 1.2 7.6 11.4 1.4 7.3 11.4 1.1 1 0 0 1 1 1 0 FHIPEP family CbiD PF01888.17 CDJ66974.1 - 1.4 8.2 7.0 2 7.7 7.0 1.2 1 0 0 1 1 1 0 CbiD PepSY_TM PF03929.16 CDJ66974.1 - 1.4 8.5 10.3 1.7 8.3 10.3 1.2 1 0 0 1 1 1 0 PepSY-associated TM region FCP1_C PF09309.10 CDJ66974.1 - 1.6 8.6 22.4 2 8.2 22.4 1.2 1 0 0 1 1 1 0 FCP1, C-terminal DUF3824 PF12868.7 CDJ66974.1 - 1.6 9.4 22.2 2.8 8.6 22.2 1.6 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF3807 PF12720.7 CDJ66974.1 - 1.7 8.9 29.3 2.2 8.6 29.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Peptidase_S49_N PF08496.10 CDJ66974.1 - 1.7 8.7 12.7 2.5 8.1 12.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BORG_CEP PF14957.6 CDJ66974.1 - 1.9 9.6 22.4 3 9.0 22.4 1.3 1 0 0 1 1 1 0 Cdc42 effector Ureide_permease PF07168.11 CDJ66974.1 - 2.1 7.0 9.9 2.2 7.0 9.9 1.2 1 0 0 1 1 1 0 Ureide permease DUF3450 PF11932.8 CDJ66974.1 - 2.1 7.6 31.1 2.4 7.4 31.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 CDJ66974.1 - 2.1 7.6 22.5 2.6 7.3 22.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dicty_REP PF05086.12 CDJ66974.1 - 2.6 5.9 20.1 2.9 5.8 20.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4175 PF13779.6 CDJ66974.1 - 2.7 5.8 33.7 3 5.6 33.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4638 PF15472.6 CDJ66974.1 - 3.1 7.5 17.8 3.6 7.3 17.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) CLN3 PF02487.17 CDJ66974.1 - 3.6 6.6 14.0 4.1 6.4 14.0 1.3 1 0 0 1 1 1 0 CLN3 protein V_ATPase_I PF01496.19 CDJ66974.1 - 3.6 5.4 18.1 3.6 5.4 18.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAT1 PF09770.9 CDJ66974.1 - 3.7 5.7 32.4 3.8 5.7 32.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPX PF03105.19 CDJ66974.1 - 3.7 7.4 32.1 4.4 7.1 32.1 1.0 1 0 0 1 1 1 0 SPX domain UPF0524 PF15823.5 CDJ66974.1 - 4.2 6.7 16.7 5.4 6.3 16.7 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 RskA PF10099.9 CDJ66974.1 - 4.2 7.6 30.7 8.7 6.6 30.6 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RR_TM4-6 PF06459.12 CDJ66974.1 - 4.6 7.0 21.3 5.3 6.8 21.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4770 PF15994.5 CDJ66974.1 - 4.9 7.3 20.7 6.3 7.0 20.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) SID-1_RNA_chan PF13965.6 CDJ66974.1 - 5.1 5.4 12.1 5.9 5.2 12.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 CDJ66974.1 - 5.4 5.2 24.5 5.7 5.1 24.5 1.0 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ66974.1 - 5.8 5.8 24.8 6.7 5.6 24.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF1387 PF07139.11 CDJ66974.1 - 6.2 6.5 27.4 7.4 6.2 27.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Apt1 PF10351.9 CDJ66974.1 - 6.4 5.5 28.7 7.3 5.3 28.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CD20 PF04103.15 CDJ66974.1 - 7.6 6.6 10.3 77 3.3 10.3 2.1 1 1 0 1 1 1 0 CD20-like family ABC2_membrane_2 PF12679.7 CDJ66974.1 - 7.9 5.7 7.5 8.9 5.5 7.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein O-antigen_lig PF13425.6 CDJ66974.1 - 8 5.1 8.6 8.3 5.1 8.6 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DcuA_DcuB PF03605.14 CDJ66974.1 - 8.9 5.1 8.3 12 4.6 8.3 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter EMC3_TMCO1 PF01956.16 CDJ66974.1 - 9.4 5.9 12.5 9.6 5.9 12.5 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Acyl_transf_3 PF01757.22 CDJ66975.1 - 0.0024 17.0 0.0 0.0028 16.8 0.0 1.0 1 0 0 1 1 1 1 Acyltransferase family Spt20 PF12090.8 CDJ66975.1 - 0.026 14.2 5.6 0.027 14.1 5.6 1.0 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ66975.1 - 0.069 12.1 2.3 0.065 12.2 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) WBP-1 PF11669.8 CDJ66975.1 - 0.077 13.6 0.8 0.079 13.6 0.8 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 Med3 PF11593.8 CDJ66975.1 - 1.2 8.2 10.1 1.2 8.2 10.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF5345 PF17280.2 CDJ66975.1 - 2.7 8.0 8.2 0.12 12.4 2.3 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5345) TFIIA PF03153.13 CDJ66976.1 - 0.00053 20.1 34.4 0.00073 19.6 34.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ABC2_membrane_2 PF12679.7 CDJ66976.1 - 0.09 12.0 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein SpoIIP PF07454.11 CDJ66976.1 - 3.2 7.1 21.7 0.15 11.5 15.5 1.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4746 PF15928.5 CDJ66976.1 - 3.7 6.9 11.5 5.5 6.3 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4407 PF14362.6 CDJ66976.1 - 5.8 6.2 21.3 0.54 9.6 16.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Tim54 PF11711.8 CDJ66976.1 - 6.2 5.5 15.2 15 4.3 11.6 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4667 PF15700.5 CDJ66977.1 - 0.0063 16.6 2.6 0.095 12.8 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ66977.1 - 0.008 15.8 11.3 0.008 15.8 11.3 2.8 3 0 0 3 3 3 2 Spt20 family EPL1 PF10513.9 CDJ66977.1 - 0.018 15.5 7.5 0.49 10.8 3.2 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF3446 PF11928.8 CDJ66977.1 - 0.027 14.7 1.2 0.027 14.7 1.2 3.0 3 0 0 3 3 3 0 Early growth response N-terminal domain PIP5K PF01504.18 CDJ66977.1 - 0.037 13.3 1.5 0.059 12.6 1.5 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase IMUP PF15761.5 CDJ66977.1 - 0.046 14.4 1.3 0.046 14.4 1.3 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein SAPS PF04499.15 CDJ66977.1 - 0.057 12.2 4.5 0.079 11.7 4.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein OATP PF03137.20 CDJ66977.1 - 0.057 11.7 1.1 0.096 11.0 0.2 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2722 PF10846.8 CDJ66977.1 - 0.06 12.3 24.9 0.01 14.9 6.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Miff PF05644.11 CDJ66977.1 - 0.13 11.8 5.6 0.06 13.0 1.9 2.0 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff DUF4834 PF16118.5 CDJ66977.1 - 0.46 11.5 15.3 0.56 11.2 0.4 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) D123 PF07065.14 CDJ66977.1 - 0.48 9.5 4.4 3.4 6.7 0.5 2.7 3 0 0 3 3 3 0 D123 Presenilin PF01080.17 CDJ66977.1 - 0.52 9.0 11.2 0.8 8.4 6.1 2.1 2 0 0 2 2 2 0 Presenilin DUF4518 PF15008.6 CDJ66977.1 - 0.61 9.2 6.7 4.8 6.3 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) DUF4598 PF15370.6 CDJ66977.1 - 1.4 9.4 9.3 2.3 8.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4598) SpoIIP PF07454.11 CDJ66977.1 - 2.7 7.4 8.7 1.3 8.4 3.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Plasmodium_Vir PF05795.11 CDJ66977.1 - 3.5 6.9 4.9 2.8 7.3 0.8 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF1117 PF06547.12 CDJ66977.1 - 8.4 7.0 5.6 7.6 7.1 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1117) zf-C2HC_2 PF13913.6 CDJ66978.1 - 0.11 12.4 3.6 0.22 11.5 3.6 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 CDJ66978.1 - 9.2 6.2 5.9 1 9.3 0.9 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif TFIIA PF03153.13 CDJ66979.1 - 0.42 10.5 24.5 0.53 10.2 24.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ66979.1 - 0.48 9.0 25.3 0.56 8.8 25.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.12 CDJ66979.1 - 1.1 9.0 9.8 1.5 8.6 9.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MRC1 PF09444.10 CDJ66979.1 - 1.3 9.5 16.5 0.039 14.5 10.0 1.7 1 1 0 1 1 1 0 MRC1-like domain Neur_chan_memb PF02932.16 CDJ66979.1 - 5.5 7.0 5.9 6.8 6.7 5.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ66979.1 - 8.6 6.2 13.9 11 5.9 13.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SR-25 PF10500.9 CDJ66980.1 - 0.00016 21.4 25.5 0.00016 21.4 25.5 3.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Mitofilin PF09731.9 CDJ66980.1 - 0.048 12.5 21.7 0.061 12.2 21.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1360 PF07098.11 CDJ66980.1 - 0.066 13.2 0.5 0.1 12.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Nramp PF01566.18 CDJ66980.1 - 0.87 8.5 10.6 1 8.2 10.6 1.1 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein FAM60A PF15396.6 CDJ66981.1 - 0.073 13.1 4.4 0.079 13.0 4.4 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Suf PF05843.14 CDJ66981.1 - 1.7 8.5 8.7 1.8 8.5 8.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MAJIN PF15077.6 CDJ66981.1 - 2.4 7.9 6.8 2.5 7.8 6.8 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein TFIIA PF03153.13 CDJ66981.1 - 5.7 6.8 18.8 6.5 6.6 18.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2298 PF10060.9 CDJ66981.1 - 5.7 5.5 9.9 7.2 5.2 9.9 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Rtf2 PF04641.12 CDJ66981.1 - 8.1 5.7 11.4 10 5.4 11.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Presenilin PF01080.17 CDJ66981.1 - 8.5 5.0 10.2 9.3 4.9 10.2 1.0 1 0 0 1 1 1 0 Presenilin NIF PF03031.18 CDJ66982.1 - 1.2e-19 70.6 1.6 2.5e-16 59.9 0.2 3.0 1 1 2 3 3 3 2 NLI interacting factor-like phosphatase SR-25 PF10500.9 CDJ66983.1 - 6 6.4 17.0 8 6.0 17.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MREG PF15812.5 CDJ66984.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 Melanoregulin Chorion_S16 PF05836.12 CDJ66984.1 - 3.4 8.0 9.9 2.5 8.4 5.3 2.5 2 1 0 2 2 2 0 Chorion protein S16 PCIF1_WW PF12237.8 CDJ66985.1 - 4.9e-24 84.9 1.9 2e-18 66.6 4.8 3.8 1 1 1 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain RskA PF10099.9 CDJ66985.1 - 4.8e-08 33.5 2.1 4.8e-08 33.5 2.1 9.6 4 2 4 9 9 9 2 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ66985.1 - 9.9e-06 25.3 21.6 2.9e-05 23.8 5.3 6.9 7 0 0 7 7 7 3 Nuclear RNA-splicing-associated protein Utp14 PF04615.13 CDJ66985.1 - 0.00094 17.9 0.0 0.00094 17.9 0.0 4.6 4 1 0 5 5 5 1 Utp14 protein Zip PF02535.22 CDJ66985.1 - 0.0011 18.2 1.2 0.0011 18.2 1.2 4.0 6 0 0 6 6 6 2 ZIP Zinc transporter AUX_IAA PF02309.16 CDJ66985.1 - 0.014 15.3 0.7 0.014 15.3 0.7 5.7 6 1 0 6 6 6 0 AUX/IAA family Gti1_Pac2 PF09729.9 CDJ66985.1 - 0.02 15.0 43.8 0.07 13.2 5.7 6.1 6 0 0 6 6 6 0 Gti1/Pac2 family SR-25 PF10500.9 CDJ66986.1 - 0.0018 18.0 23.1 0.0019 17.8 23.1 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SMYLE_N PF18615.1 CDJ66986.1 - 1.2 8.6 21.6 1.4 8.4 21.6 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain RskA PF10099.9 CDJ66986.1 - 7.7 6.8 24.8 16 5.8 24.8 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA YABBY PF04690.13 CDJ66986.1 - 8.6 6.9 20.5 9.7 6.7 20.5 1.1 1 0 0 1 1 1 0 YABBY protein CN_hydrolase PF00795.22 CDJ66988.1 - 0.019 14.3 0.2 0.023 14.0 0.2 1.1 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase Peptidase_S66 PF02016.15 CDJ66988.1 - 0.23 11.6 0.3 0.28 11.3 0.3 1.1 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain SUIM_assoc PF16619.5 CDJ66988.1 - 1 9.5 12.4 1.6 8.8 12.4 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ66988.1 - 6.4 6.3 11.5 7 6.2 11.5 1.1 1 0 0 1 1 1 0 Spt20 family Kelch_6 PF13964.6 CDJ66989.1 - 1.3e-22 79.3 0.0 5.6e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CDJ66989.1 - 7.1e-22 76.7 0.3 2.1e-10 40.0 0.0 3.3 2 1 1 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CDJ66989.1 - 2.8e-17 62.5 0.1 4.7e-09 36.1 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ66989.1 - 6.8e-12 45.4 0.1 5.1e-06 26.6 0.1 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ66989.1 - 5.5e-06 26.1 0.1 0.04 13.9 0.0 3.1 3 1 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CDJ66989.1 - 5.6e-06 26.2 0.3 0.58 10.2 0.0 3.6 4 0 0 4 4 4 2 Kelch motif DUF1668 PF07893.13 CDJ66989.1 - 0.095 12.0 0.0 0.14 11.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1668) FAD_binding_6 PF00970.24 CDJ66990.1 - 1.3e-07 31.9 0.1 2.7e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain IMUP PF15761.5 CDJ66990.1 - 0.04 14.6 5.1 0.053 14.2 5.1 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ66990.1 - 0.1 12.2 12.5 0.13 11.9 12.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2371 PF10177.9 CDJ66990.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF755 PF05501.11 CDJ66990.1 - 2 8.7 13.6 3.2 8.0 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ribosomal_60s PF00428.19 CDJ66991.1 - 0.00088 19.8 23.9 0.056 14.0 11.5 2.5 2 0 0 2 2 2 2 60s Acidic ribosomal protein WD40 PF00400.32 CDJ66991.1 - 0.0019 19.0 0.0 0.0053 17.6 0.0 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat Bile_Hydr_Trans PF04775.14 CDJ66991.1 - 0.083 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region MPS2 PF17060.5 CDJ66991.1 - 0.092 12.0 0.8 0.14 11.4 0.8 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Tic110 PF16940.5 CDJ66991.1 - 1.4 7.3 14.2 0.13 10.7 3.5 2.1 2 0 0 2 2 2 0 Chloroplast envelope transporter RAP1 PF07218.11 CDJ66991.1 - 1.8 6.8 6.7 13 3.9 5.1 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ66991.1 - 3 7.4 19.3 1.5 8.4 17.1 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3597 PF12200.8 CDJ66991.1 - 3.9 8.0 8.1 1.4 9.5 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) DUF4179 PF13786.6 CDJ66991.1 - 4.1 7.9 8.4 3.2 8.3 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) PCM1_C PF15717.5 CDJ66992.1 - 1.1 7.8 8.7 1.2 7.8 8.7 1.0 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Plasmodium_Vir PF05795.11 CDJ66992.1 - 1.6 8.1 3.8 1.6 8.1 3.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein XRN_M PF17846.1 CDJ66992.1 - 4.4 6.1 4.5 5 6.0 4.5 1.0 1 0 0 1 1 1 0 Xrn1 helical domain SR-25 PF10500.9 CDJ66992.1 - 7.6 6.1 14.1 7.9 6.0 13.5 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ66993.1 - 2.7 8.1 31.9 3.5 7.7 31.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Suf PF05843.14 CDJ66994.1 - 0.18 11.7 2.9 0.22 11.4 2.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ66994.1 - 0.41 10.2 11.0 0.51 9.9 11.0 1.2 1 0 0 1 1 1 0 Spt20 family VSG_B PF13206.6 CDJ66995.1 - 0.1 11.8 11.5 0.12 11.6 11.5 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain SID-1_RNA_chan PF13965.6 CDJ66995.1 - 0.16 10.3 0.2 0.17 10.2 0.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Paramyxo_ncap PF00973.19 CDJ66995.1 - 2.2 7.1 8.0 2.4 7.0 8.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SARAF PF06682.12 CDJ66996.1 - 0.037 13.7 1.6 0.037 13.7 1.6 1.2 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis RAP PF08373.10 CDJ66997.1 - 1.9e-12 47.1 0.0 9.3e-12 44.9 0.0 2.3 1 0 0 1 1 1 1 RAP domain SUIM_assoc PF16619.5 CDJ66998.1 - 8.2e-05 22.6 0.0 0.014 15.4 0.3 17.3 12 4 2 14 14 14 6 Unstructured region C-term to UIM in Ataxin3 Thiolase_N PF00108.23 CDJ67002.1 - 8.7e-56 189.2 0.0 3.6e-42 144.5 0.0 2.1 2 0 0 2 2 2 2 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 CDJ67002.1 - 0.0013 18.3 12.9 0.0014 18.3 2.6 3.3 2 2 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CDJ67002.1 - 0.0028 17.5 9.1 0.048 13.5 0.2 2.9 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Med15 PF09606.10 CDJ67002.1 - 0.025 13.3 3.7 0.036 12.8 3.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PhnG PF06754.12 CDJ67003.1 - 0.0023 17.9 7.6 0.34 10.9 0.8 2.4 1 1 1 2 2 2 2 Phosphonate metabolism protein PhnG CDK2AP PF09806.9 CDJ67003.1 - 0.0096 16.0 2.6 0.018 15.2 2.6 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein DUF3446 PF11928.8 CDJ67003.1 - 0.069 13.5 12.7 0.11 12.8 12.7 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain Ubiq_cyt_C_chap PF03981.12 CDJ67003.1 - 0.11 12.6 0.8 5.8 7.0 0.1 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C chaperone RNA_pol_N PF01194.17 CDJ67003.1 - 0.21 11.9 0.6 15 5.9 0.1 2.8 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit DUF4709 PF15821.5 CDJ67003.1 - 0.46 10.8 2.8 2 8.8 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) DUF3618 PF12277.8 CDJ67003.1 - 0.77 10.1 6.8 7.4 6.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) SR-25 PF10500.9 CDJ67003.1 - 3.9 7.0 26.9 5.4 6.6 26.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pro_Al_protease PF02983.14 CDJ67003.1 - 5.2 7.2 7.3 22 5.2 0.8 2.4 2 0 0 2 2 2 0 Alpha-lytic protease prodomain SAC3_GANP PF03399.16 CDJ67004.1 - 4.8e-16 59.0 10.6 4.8e-16 59.0 10.6 4.0 2 1 1 3 3 3 1 SAC3/GANP family DUF3446 PF11928.8 CDJ67004.1 - 0.0071 16.6 9.0 0.0071 16.6 9.0 6.8 5 1 0 6 6 6 1 Early growth response N-terminal domain ELMO_CED12 PF04727.13 CDJ67005.1 - 3.1e-12 47.0 23.1 2.8e-11 43.9 11.5 3.8 2 1 1 3 3 3 2 ELMO/CED-12 family Spt20 PF12090.8 CDJ67005.1 - 0.0005 19.8 13.1 0.0005 19.8 13.1 5.0 3 1 1 5 5 5 2 Spt20 family DUF2722 PF10846.8 CDJ67005.1 - 0.0011 18.0 9.1 0.0011 18.0 9.1 5.2 3 2 2 5 5 5 1 Protein of unknown function (DUF2722) FAM60A PF15396.6 CDJ67005.1 - 0.061 13.3 28.2 0.47 10.4 0.3 3.3 3 0 0 3 3 3 0 Protein Family FAM60A DUF908 PF06012.12 CDJ67005.1 - 0.068 12.6 28.1 0.32 10.4 22.3 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DUF572 PF04502.13 CDJ67005.1 - 0.78 9.3 32.9 3.6 7.1 23.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF572) CCSAP PF15748.5 CDJ67005.1 - 0.81 9.8 36.9 0.029 14.5 18.3 3.5 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated Zip PF02535.22 CDJ67005.1 - 2 7.6 10.2 8.8 5.4 7.2 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter GREB1 PF15782.5 CDJ67005.1 - 7.9 3.4 26.9 0.7 6.9 16.2 2.3 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer DUF2722 PF10846.8 CDJ67007.1 - 0.00013 21.1 2.4 0.00013 21.1 2.4 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ67007.1 - 2.5 6.7 61.8 2.9 6.5 40.8 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal LAP1C PF05609.12 CDJ67010.1 - 6 5.9 53.5 8.2 5.4 53.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3995 PF13160.6 CDJ67011.1 - 0.16 12.3 8.9 0.75 10.2 0.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) DUF4551 PF15087.6 CDJ67011.1 - 1.8 7.3 31.8 2.2 7.0 31.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SUIM_assoc PF16619.5 CDJ67012.1 - 3.4 7.8 14.5 8.1 6.6 14.5 1.7 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DS PF01916.17 CDJ67013.1 - 4.8e-101 337.8 0.0 2.4e-100 335.5 0.0 1.9 1 1 0 1 1 1 1 Deoxyhypusine synthase DUF2722 PF10846.8 CDJ67013.1 - 0.00025 20.2 4.6 0.00025 20.2 4.6 3.2 2 1 1 3 3 2 1 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ67013.1 - 0.00034 20.3 50.5 0.022 14.4 12.3 3.3 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Velvet PF11754.8 CDJ67013.1 - 0.011 15.7 0.3 0.011 15.7 0.3 3.1 2 1 0 2 2 1 0 Velvet factor DUF913 PF06025.12 CDJ67013.1 - 0.023 13.7 5.9 0.093 11.7 0.5 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF1635 PF07795.11 CDJ67013.1 - 0.028 14.3 31.2 0.13 12.1 7.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) Coilin_N PF15862.5 CDJ67013.1 - 0.034 14.0 0.6 0.034 14.0 0.6 3.1 2 1 1 3 3 2 0 Coilin N-terminus MPM1 PF17234.2 CDJ67013.1 - 0.3 11.3 17.7 0.061 13.6 3.4 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 ASD2 PF08687.11 CDJ67013.1 - 0.58 9.7 19.6 0.86 9.1 7.0 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Afi1 PF07792.12 CDJ67013.1 - 0.59 10.6 7.6 3.8 8.0 0.9 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Neur_chan_memb PF02932.16 CDJ67013.1 - 3.3 7.7 16.1 1.9 8.5 3.4 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Barttin PF15462.6 CDJ67013.1 - 4.2 7.1 19.4 1.3 8.7 7.3 2.4 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Cwf_Cwc_15 PF04889.12 CDJ67013.1 - 4.2 7.0 15.3 0.34 10.6 3.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop25 PF09805.9 CDJ67013.1 - 4.4 7.8 16.0 4.2 7.8 5.2 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) FAM60A PF15396.6 CDJ67013.1 - 5.2 7.0 19.0 2.5 8.0 4.4 2.3 2 0 0 2 2 2 0 Protein Family FAM60A DUF4569 PF15133.6 CDJ67013.1 - 5.3 6.7 24.6 0.083 12.6 8.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) Apt1 PF10351.9 CDJ67013.1 - 5.8 5.7 23.3 1.3 7.8 6.1 2.3 3 0 0 3 3 3 0 Golgi-body localisation protein domain DUF572 PF04502.13 CDJ67013.1 - 8.6 5.9 16.8 3.9 7.0 3.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) TFIIA PF03153.13 CDJ67013.1 - 9.5 6.1 42.2 8.9 6.2 22.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ67014.1 - 0.15 11.6 16.3 0.075 12.6 2.9 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF4692 PF15763.5 CDJ67014.1 - 0.94 9.9 13.7 0.15 12.6 4.9 2.7 3 0 0 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) YajC PF02699.15 CDJ67014.1 - 2.5 8.0 18.1 2.2 8.2 1.0 3.2 3 0 0 3 3 3 0 Preprotein translocase subunit Miga PF10265.9 CDJ67014.1 - 4.2 6.2 9.8 6.3 5.7 9.8 1.3 1 0 0 1 1 1 0 Mitoguardin SUIM_assoc PF16619.5 CDJ67014.1 - 6.3 6.9 47.7 2.3 8.3 5.5 3.8 2 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ67015.1 - 0.0094 15.6 2.7 0.0094 15.6 2.7 1.9 2 0 0 2 2 2 1 Spt20 family RskA PF10099.9 CDJ67015.1 - 0.01 16.2 10.3 0.01 16.2 10.3 4.1 2 1 1 3 3 3 0 Anti-sigma-K factor rskA MID_MedPIWI PF18296.1 CDJ67015.1 - 0.045 13.5 1.5 0.079 12.7 0.8 1.6 2 0 0 2 2 2 0 MID domain of medPIWI SR-25 PF10500.9 CDJ67015.1 - 0.94 9.0 15.5 0.067 12.8 8.5 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4805 PF16063.5 CDJ67015.1 - 5.5 6.2 9.6 0.65 9.3 3.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) Proteasome PF00227.26 CDJ67016.1 - 3.1e-59 199.7 0.0 3.8e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ67016.1 - 2e-13 49.7 0.2 3.4e-13 49.0 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GM_CSF PF01109.17 CDJ67016.1 - 0.023 14.9 0.2 0.049 13.8 0.1 1.6 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor DSPc PF00782.20 CDJ67017.1 - 2.4e-24 85.6 0.0 3.4e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDJ67017.1 - 0.0014 18.7 0.1 0.003 17.7 0.1 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CDJ67017.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HTH_32 PF13565.6 CDJ67017.1 - 0.09 13.4 0.1 0.43 11.2 0.1 2.2 1 0 0 1 1 1 0 Homeodomain-like domain Cpn10 PF00166.21 CDJ67018.1 - 0.36 10.9 14.3 1.4 9.0 0.5 3.9 2 1 1 3 3 3 0 Chaperonin 10 Kd subunit Sec1 PF00995.23 CDJ67019.1 - 5.7e-16 58.9 0.0 5.9e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PEP_hydrolase PF09370.10 CDJ67019.1 - 0.089 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Sec1 PF00995.23 CDJ67020.1 - 9.3e-81 272.8 1.4 1.1e-80 272.5 1.4 1.0 1 0 0 1 1 1 1 Sec1 family YlbD_coat PF14071.6 CDJ67020.1 - 0.035 14.3 0.5 0.27 11.5 0.4 2.1 2 0 0 2 2 2 0 Putative coat protein Dor1 PF04124.12 CDJ67021.1 - 1.2e-24 86.7 1.1 1.7e-24 86.1 1.1 1.2 1 0 0 1 1 1 1 Dor1-like family Exo84_C PF16528.5 CDJ67021.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CDJ67021.1 - 0.026 14.6 0.1 0.082 13.0 0.1 1.8 1 0 0 1 1 1 0 Vps51/Vps67 PK PF00224.21 CDJ67022.1 - 9.8e-146 485.1 0.7 1.3e-145 484.7 0.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CDJ67022.1 - 4.2e-32 110.8 0.4 1e-31 109.6 0.4 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CDJ67022.1 - 0.0045 16.1 1.0 0.011 14.9 0.1 2.1 2 1 1 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family Vps8 PF12816.7 CDJ67022.1 - 0.041 13.4 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 Adap_comp_sub PF00928.21 CDJ67023.1 - 1.4e-09 37.7 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ67023.1 - 0.19 11.7 0.3 0.71 9.8 0.1 2.0 2 0 0 2 2 2 0 Clathrin adaptor complex small chain zf-C4H2 PF10146.9 CDJ67024.1 - 0.52 10.6 4.8 0.81 10.0 4.8 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein HAP1_N PF04849.13 CDJ67024.1 - 1.9 7.6 22.6 0.054 12.7 8.2 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Spc7 PF08317.11 CDJ67024.1 - 4.6 6.0 21.4 5.9 5.7 21.0 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 CDJ67024.1 - 6.9 5.9 16.1 9.9 5.4 16.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TctA PF01970.16 CDJ67025.1 - 0.0016 17.3 0.1 0.0016 17.3 0.1 1.6 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctA family DUF4064 PF13273.6 CDJ67025.1 - 0.36 11.1 6.7 0.61 10.4 0.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Pox_A14 PF05767.12 CDJ67025.1 - 1.2 9.4 8.1 0.11 12.6 2.6 2.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PARM PF17061.5 CDJ67025.1 - 4.3 7.4 15.2 0.86 9.7 11.4 1.6 2 0 0 2 2 2 0 PARM dCMP_cyt_deam_1 PF00383.23 CDJ67027.1 - 2e-07 30.8 2.5 3.5e-07 30.0 0.6 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region RskA PF10099.9 CDJ67027.1 - 7.5e-06 26.4 14.9 0.0011 19.2 0.0 2.6 1 1 1 2 2 2 1 Anti-sigma-K factor rskA MafB19-deam PF14437.6 CDJ67027.1 - 0.00014 21.7 0.1 0.00014 21.7 0.1 1.8 2 0 0 2 2 1 1 MafB19-like deaminase TFIIA PF03153.13 CDJ67027.1 - 0.0003 20.9 43.2 0.00047 20.3 43.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3807 PF12720.7 CDJ67027.1 - 0.018 15.4 20.8 0.03 14.6 20.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CDC45 PF02724.14 CDJ67027.1 - 0.19 10.0 9.8 0.2 9.9 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 CDJ67027.1 - 0.23 11.5 12.4 0.3 11.1 12.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RIFIN PF02009.16 CDJ67027.1 - 0.25 11.2 8.6 0.42 10.5 8.6 1.3 1 0 0 1 1 1 0 Rifin SAPS PF04499.15 CDJ67027.1 - 0.26 10.0 7.4 0.26 10.0 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2151 PF10221.9 CDJ67027.1 - 0.27 9.8 8.5 0.32 9.5 8.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Zip PF02535.22 CDJ67027.1 - 0.3 10.2 5.9 0.43 9.8 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 CDJ67027.1 - 0.31 10.0 7.7 0.4 9.6 7.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PAT1 PF09770.9 CDJ67027.1 - 0.51 8.6 36.8 0.59 8.3 36.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 CDJ67027.1 - 0.66 9.5 25.1 0.89 9.1 25.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Virul_Fac PF10139.9 CDJ67027.1 - 0.78 7.9 11.2 0.93 7.6 11.2 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor RR_TM4-6 PF06459.12 CDJ67027.1 - 0.84 9.4 19.1 1.3 8.8 19.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOG2 PF10428.9 CDJ67027.1 - 0.95 8.6 17.5 1.1 8.4 17.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 CDJ67027.1 - 1.3 6.1 18.2 1.3 6.1 18.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5427 PF10310.9 CDJ67027.1 - 1.3 7.9 21.7 1.8 7.4 21.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 CDJ67027.1 - 1.4 7.8 14.7 1.7 7.5 14.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Endostatin PF06482.11 CDJ67027.1 - 1.6 8.1 16.3 2.2 7.7 16.3 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Presenilin PF01080.17 CDJ67027.1 - 1.7 7.4 23.2 2.3 6.9 23.2 1.2 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 CDJ67027.1 - 2.7 7.9 17.9 3.6 7.4 17.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Plasmodium_Vir PF05795.11 CDJ67027.1 - 3.8 6.8 11.8 4.6 6.5 11.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein XAP5 PF04921.14 CDJ67027.1 - 4 7.2 12.4 6.6 6.5 12.4 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF4175 PF13779.6 CDJ67027.1 - 4.2 5.2 40.0 7.6 4.3 40.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Use1 PF09753.9 CDJ67027.1 - 4.3 7.0 15.2 5.9 6.5 15.2 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 ALMT PF11744.8 CDJ67027.1 - 5 5.8 10.2 6.2 5.5 10.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 CDJ67027.1 - 6.8 4.7 19.2 7.9 4.5 19.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Borrelia_P83 PF05262.11 CDJ67027.1 - 7.5 4.9 17.1 8.9 4.7 17.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RRM_1 PF00076.22 CDJ67029.1 - 1.1e-05 25.1 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 CDJ67029.1 - 0.052 13.5 16.4 0.059 13.4 16.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CDJ67029.1 - 0.99 8.3 27.8 1.2 8.0 27.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ67029.1 - 2.3 7.8 21.6 3.1 7.3 21.6 1.1 1 0 0 1 1 1 0 Spt20 family zf-B_box PF00643.24 CDJ67031.1 - 0.00067 19.8 6.1 0.00067 19.8 6.1 1.7 2 0 0 2 2 2 1 B-box zinc finger DUF1043 PF06295.12 CDJ67031.1 - 0.12 12.4 1.5 0.16 11.9 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FPN1 PF06963.12 CDJ67032.1 - 0.056 12.0 1.8 0.06 11.9 1.8 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Shadoo PF14999.6 CDJ67032.1 - 0.54 10.4 10.8 0.6 10.2 10.8 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Wzz PF02706.15 CDJ67032.1 - 1 9.7 6.7 1.2 9.4 6.7 1.1 1 0 0 1 1 1 0 Chain length determinant protein RskA PF10099.9 CDJ67032.1 - 2.6 8.3 22.1 3.5 7.9 22.1 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA LPP20 PF02169.16 CDJ67032.1 - 5.2 7.5 13.6 6.4 7.2 13.6 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein R_equi_Vir PF05526.11 CDJ67032.1 - 6 6.7 8.7 6.5 6.6 8.7 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF4179 PF13786.6 CDJ67032.1 - 6.2 7.4 8.8 11 6.5 8.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) DUF1845 PF08900.11 CDJ67033.1 - 0.00017 21.4 1.5 0.00021 21.1 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1845) SAPIS-gp6 PF16722.5 CDJ67033.1 - 0.00095 19.5 5.1 0.0014 19.0 5.1 1.3 1 0 0 1 1 1 1 Pathogenicity island protein gp6 in Staphylococcus Spt20 PF12090.8 CDJ67033.1 - 0.0099 15.5 3.8 0.011 15.4 3.8 1.2 1 0 0 1 1 1 1 Spt20 family DUF3040 PF11239.8 CDJ67033.1 - 0.011 15.9 0.0 0.021 15.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) AlaDh_PNT_C PF01262.21 CDJ67033.1 - 0.022 14.1 0.1 0.027 13.8 0.1 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4866 PF16160.5 CDJ67033.1 - 0.043 13.1 0.1 0.058 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4866) Dala_Dala_lig_N PF01820.21 CDJ67033.1 - 0.072 13.6 0.1 0.096 13.2 0.1 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus FTZ PF03867.14 CDJ67033.1 - 0.17 11.4 0.8 0.21 11.1 0.8 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Nbs1_C PF08599.10 CDJ67033.1 - 0.31 11.2 2.2 0.53 10.5 2.2 1.5 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 DUF2967 PF11179.8 CDJ67033.1 - 10 4.1 6.4 13 3.8 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) RNA_pol_L PF01193.24 CDJ67034.1 - 7.2e-08 31.8 0.0 7.3e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NAP PF00956.18 CDJ67035.1 - 8.6e-08 31.7 2.3 1e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) CENP-B_dimeris PF09026.10 CDJ67035.1 - 0.38 11.2 10.5 0.48 10.8 10.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YL1 PF05764.13 CDJ67035.1 - 0.46 10.6 7.3 0.41 10.7 7.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Pes-10 PF07149.11 CDJ67035.1 - 0.91 8.5 3.2 0.84 8.6 3.2 1.0 1 0 0 1 1 1 0 Pes-10 NOA36 PF06524.12 CDJ67035.1 - 1.9 7.7 7.5 2 7.7 7.5 1.1 1 0 0 1 1 1 0 NOA36 protein SLC12 PF03522.15 CDJ67036.1 - 1.9 7.4 10.5 4.2 6.3 9.9 1.7 2 0 0 2 2 2 0 Solute carrier family 12 Integrase_H2C2 PF17921.1 CDJ67037.1 - 3.9e-11 42.9 3.6 7e-11 42.1 2.3 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain zf-CCHC PF00098.23 CDJ67037.1 - 2.6e-08 33.6 10.9 0.00033 20.6 2.2 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ67037.1 - 0.0019 18.1 2.7 0.081 12.9 0.1 2.4 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ67037.1 - 0.0022 17.8 0.7 0.0022 17.8 0.7 2.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ67037.1 - 0.011 15.4 0.7 0.011 15.4 0.7 2.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DnaJ_CXXCXGXG PF00684.19 CDJ67037.1 - 0.03 14.7 3.6 0.065 13.6 3.6 1.5 1 0 0 1 1 1 0 DnaJ central domain Retrotrans_gag PF03732.17 CDJ67037.1 - 0.059 13.7 0.1 0.41 11.0 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein zf-H2C2 PF09337.10 CDJ67037.1 - 0.15 12.3 0.3 0.15 12.3 0.3 3.1 4 0 0 4 4 4 0 H2C2 zinc finger zf-CCHC_4 PF14392.6 CDJ67037.1 - 0.39 10.5 5.7 5.7 6.7 0.6 2.5 2 0 0 2 2 2 0 Zinc knuckle Kringle PF00051.18 CDJ67038.1 - 8e-11 42.1 1.6 1.6e-10 41.2 1.6 1.5 1 0 0 1 1 1 1 Kringle domain Spt20 PF12090.8 CDJ67039.1 - 0.0005 19.7 13.9 0.0007 19.3 13.9 1.1 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ67039.1 - 0.0037 17.3 11.9 0.0043 17.1 11.9 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ67039.1 - 0.0053 15.8 9.0 0.0071 15.4 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Neur_chan_memb PF02932.16 CDJ67039.1 - 0.38 10.8 2.3 0.48 10.4 2.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3138 PF11336.8 CDJ67039.1 - 0.65 8.5 12.8 0.82 8.2 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Presenilin PF01080.17 CDJ67039.1 - 1.4 7.6 4.0 1.6 7.4 4.0 1.1 1 0 0 1 1 1 0 Presenilin PerC PF06069.11 CDJ67040.1 - 0.042 14.1 0.8 0.073 13.3 0.8 1.4 1 0 0 1 1 1 0 PerC transcriptional activator XTBD PF11952.8 CDJ67040.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD DUF4179 PF13786.6 CDJ67040.1 - 0.26 11.8 2.1 3.2 8.3 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) DUF1682 PF07946.14 CDJ67041.1 - 0.0049 16.1 0.5 0.0049 16.1 0.5 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1682) Dpy-30 PF05186.13 CDJ67041.1 - 0.2 11.4 7.0 0.23 11.2 0.1 2.7 3 0 0 3 3 3 0 Dpy-30 motif PRIMA1 PF16101.5 CDJ67042.1 - 0.16 12.0 3.8 1.1 9.3 3.8 2.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Proteasome PF00227.26 CDJ67044.1 - 1.9e-49 167.7 0.1 2.4e-49 167.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-C2H2_jaz PF12171.8 CDJ67045.1 - 7.5e-05 22.9 1.4 0.00014 22.0 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ67045.1 - 0.00012 22.4 1.8 0.00023 21.5 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 CDJ67045.1 - 0.28 11.0 0.9 0.63 9.9 0.9 1.5 1 0 0 1 1 1 0 U1 zinc finger DUF724 PF05266.14 CDJ67045.1 - 0.44 10.4 3.2 0.17 11.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF3381 PF11861.8 CDJ67045.1 - 0.76 9.6 10.4 0.35 10.7 5.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) XRN_M PF17846.1 CDJ67045.1 - 1.5 7.7 4.4 1.3 7.9 0.3 2.0 2 0 0 2 2 2 0 Xrn1 helical domain DASH_Spc19 PF08287.11 CDJ67045.1 - 6.3 6.7 8.7 0.21 11.5 1.0 2.4 3 0 0 3 3 3 0 Spc19 Mcm10 PF09332.11 CDJ67047.1 - 0.0029 17.1 19.3 0.0029 17.1 19.3 2.2 2 0 0 2 2 2 1 Mcm10 replication factor DUF5421 PF17458.2 CDJ67047.1 - 0.0062 16.0 4.1 0.0062 16.0 4.1 3.8 3 1 1 4 4 4 2 Family of unknown function (DUF5421) Mak10 PF04112.13 CDJ67047.1 - 3.4 7.2 5.5 32 4.0 0.1 2.6 2 0 0 2 2 2 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase WD40 PF00400.32 CDJ67048.1 - 0.00056 20.7 1.2 0.12 13.3 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat BBS2_N PF14781.6 CDJ67048.1 - 0.00058 19.7 1.2 0.023 14.6 0.2 2.1 1 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal ANAPC4_WD40 PF12894.7 CDJ67048.1 - 0.0062 16.8 0.1 0.22 11.8 0.0 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Hydin_ADK PF17213.3 CDJ67048.1 - 0.026 14.8 2.3 0.033 14.5 2.3 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Med15 PF09606.10 CDJ67048.1 - 0.27 9.9 12.0 0.31 9.7 12.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ67048.1 - 0.33 10.9 10.4 0.39 10.6 10.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YajC PF02699.15 CDJ67048.1 - 0.36 10.8 5.9 4.5 7.2 0.4 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit Ribosomal_60s PF00428.19 CDJ67048.1 - 0.9 10.2 17.8 0.31 11.7 7.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Phostensin_N PF13916.6 CDJ67048.1 - 6.6 7.2 10.4 6.6 7.1 1.1 2.2 1 1 1 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Surface_antigen PF11054.8 CDJ67049.1 - 6.4e-19 68.6 0.0 7.6e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen rve PF00665.26 CDJ67050.1 - 5.2e-13 49.2 0.0 1.3e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 CDJ67050.1 - 1e-12 48.0 0.0 2.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 CDJ67050.1 - 1.3e-12 47.7 0.0 2.7e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ67050.1 - 2.4e-11 44.1 0.0 8e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ67050.1 - 7.7e-10 39.2 0.0 1.6e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ67050.1 - 0.00091 19.5 0.0 0.0026 18.0 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ67050.1 - 0.04 13.7 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease D-ser_dehydrat PF14031.6 CDJ67050.1 - 0.16 12.7 0.0 4.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Putative serine dehydratase domain Rad50_zn_hook PF04423.14 CDJ67051.1 - 0.67 9.8 6.8 4.6 7.1 6.8 1.9 1 1 0 1 1 1 0 Rad50 zinc hook motif Minor_tail_Z PF06763.11 CDJ67051.1 - 1.7 8.4 8.1 1.7 8.4 8.1 1.0 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) DUF3313 PF11769.8 CDJ67051.1 - 2.9 7.7 5.2 2.8 7.7 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Ldh_1_N PF00056.23 CDJ67052.1 - 1.5e-37 128.8 0.2 1.7e-37 128.6 0.2 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 CDJ67052.1 - 2.8e-06 27.0 1.4 9.8e-05 22.0 0.1 2.4 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.19 CDJ67052.1 - 0.0086 15.1 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HTH_31 PF13560.6 CDJ67052.1 - 0.096 13.0 0.4 0.23 11.9 0.4 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain F420_oxidored PF03807.17 CDJ67052.1 - 0.36 11.4 3.8 1.2 9.7 1.6 2.4 1 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent IMP2_N PF18590.1 CDJ67053.1 - 6.6e-14 52.2 0.0 1.2e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain COX6B PF02297.17 CDJ67054.1 - 3e-05 24.2 4.6 4.5e-05 23.6 4.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UTRA PF07702.13 CDJ67054.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 2 0 0 2 2 2 0 UTRA domain DUF627 PF04781.12 CDJ67054.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF627) PDZ_3 PF17815.1 CDJ67056.1 - 5.8e-35 120.3 0.0 9.7e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 CDJ67056.1 - 1.1e-19 71.9 1.6 3.4e-19 70.2 1.6 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CDJ67056.1 - 6.3e-12 45.8 0.0 5.8e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 Trypsin PDZ_6 PF17820.1 CDJ67056.1 - 0.0007 19.4 0.1 0.39 10.6 0.0 3.1 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CDJ67056.1 - 0.074 13.4 0.0 3.2 8.1 0.0 3.0 3 0 0 3 3 3 0 PDZ domain Med4 PF10018.9 CDJ67057.1 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1604 PF07713.13 CDJ67058.1 - 5.3e-11 42.2 1.4 1.6e-10 40.6 1.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1604) CutA1 PF03091.15 CDJ67058.1 - 0.13 12.2 0.5 0.26 11.1 0.5 1.6 1 1 0 1 1 1 0 CutA1 divalent ion tolerance protein Methyltransf_25 PF13649.6 CDJ67059.1 - 6.3e-12 46.0 0.1 2.9e-11 43.9 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ67059.1 - 2.9e-10 40.2 0.1 9.8e-10 38.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CDJ67059.1 - 5.1e-10 39.2 0.0 8.5e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CDJ67059.1 - 1.5e-09 38.3 0.1 7.5e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ67059.1 - 2.9e-05 24.0 0.0 8.5e-05 22.4 0.0 1.7 1 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CDJ67059.1 - 0.0001 21.7 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CDJ67059.1 - 0.00022 20.8 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 CDJ67059.1 - 0.003 17.5 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CDJ67059.1 - 0.0035 16.3 0.0 0.0087 15.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 CDJ67059.1 - 0.0044 16.4 0.0 0.021 14.1 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 CDJ67059.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DOT1 PF08123.13 CDJ67059.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 CDJ67059.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 CDJ67059.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.16 CDJ67059.1 - 0.032 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_18 PF12847.7 CDJ67059.1 - 0.033 14.1 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ67059.1 - 0.034 14.9 0.0 0.073 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 CDJ67059.1 - 0.053 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase BsuPI PF12690.7 CDJ67059.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Intracellular proteinase inhibitor Methyltransf_24 PF13578.6 CDJ67059.1 - 0.066 14.2 0.0 0.13 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ67059.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_2 PF00891.18 CDJ67059.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Ras PF00071.22 CDJ67060.1 - 5.3e-60 201.7 0.2 6.3e-60 201.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ67060.1 - 1.6e-34 118.7 0.1 2.6e-34 118.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ67060.1 - 8.8e-14 51.3 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ67060.1 - 6e-06 26.3 0.0 1.5e-05 25.0 0.0 1.6 1 1 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ67060.1 - 5.9e-05 22.5 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ67060.1 - 0.00029 20.8 0.2 0.11 12.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CDJ67060.1 - 0.00069 19.1 0.0 0.0014 18.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CDJ67060.1 - 0.0044 16.6 0.4 0.012 15.2 0.2 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CDJ67060.1 - 0.034 14.4 0.0 0.075 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ67060.1 - 0.036 14.4 0.3 0.073 13.5 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain SNF2_N PF00176.23 CDJ67060.1 - 0.085 11.6 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain DAP3 PF10236.9 CDJ67060.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Cu_amine_oxid PF01179.20 CDJ67061.1 - 4.5e-73 246.5 0.4 8e-73 245.7 0.4 1.4 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain MAM PF00629.23 CDJ67061.1 - 2.2e-30 105.7 0.0 4.3e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DUF1965 PF09248.10 CDJ67061.1 - 0.038 13.8 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Syntaxin-6_N PF09177.11 CDJ67063.1 - 3.8 8.1 10.7 4.1 8.0 0.3 3.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Phosphonate-bd PF12974.7 CDJ67065.1 - 0.063 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Tir_receptor_C PF07489.11 CDJ67067.1 - 0.074 13.0 0.2 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Brix PF04427.18 CDJ67068.1 - 8.2e-28 97.8 0.0 1.2e-27 97.3 0.0 1.3 1 0 0 1 1 1 1 Brix domain SAC3_GANP PF03399.16 CDJ67071.1 - 2.9e-06 26.9 9.0 2.3e-05 23.9 3.3 2.7 1 1 1 2 2 2 2 SAC3/GANP family AnfO_nitrog PF09582.10 CDJ67071.1 - 0.18 11.2 0.1 0.31 10.4 0.1 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DnaJ PF00226.31 CDJ67072.1 - 4.2e-13 49.2 0.2 4.2e-13 49.2 0.2 1.7 2 0 0 2 2 2 1 DnaJ domain Anillin PF08174.11 CDJ67072.1 - 0.051 14.0 0.5 0.13 12.6 0.5 1.8 1 1 0 1 1 1 0 Cell division protein anillin SNARE_assoc PF09335.11 CDJ67076.1 - 8.5e-08 32.7 6.8 0.00081 19.9 0.0 3.0 3 0 0 3 3 3 2 SNARE associated Golgi protein EOS1 PF12326.8 CDJ67076.1 - 0.31 10.9 3.4 7.9 6.4 0.2 2.4 2 0 0 2 2 2 0 N-glycosylation protein DUF5058 PF16481.5 CDJ67076.1 - 0.9 9.2 5.9 1.3 8.6 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5058) GTA_holin_3TM PF11351.8 CDJ67076.1 - 2.6 8.6 9.8 3.2 8.3 0.1 3.5 4 0 0 4 4 4 0 Holin of 3TMs, for gene-transfer release DUF3824 PF12868.7 CDJ67077.1 - 6.8 7.4 14.8 1 10.0 9.4 2.5 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Chromo PF00385.24 CDJ67078.1 - 8.5e-13 48.0 0.1 2.4e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 CDJ67079.1 - 3.6e-26 91.1 0.1 9.9e-26 89.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ67079.1 - 1e-18 67.7 0.0 1.8e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ67079.1 - 3e-17 62.5 1.1 6.5e-17 61.4 1.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ67079.1 - 9.9e-16 58.0 0.0 4.8e-15 55.8 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 CDJ67079.1 - 2.3e-15 56.8 0.0 7.5e-15 55.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 CDJ67079.1 - 1.7e-07 31.1 0.0 4.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ67079.1 - 8.7e-07 29.5 0.0 1.8e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ67079.1 - 1e-06 29.2 0.0 2.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 CDJ67079.1 - 6.5e-06 26.0 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CDJ67079.1 - 0.00067 19.8 0.3 0.0016 18.6 0.3 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDJ67079.1 - 0.035 13.9 0.1 1.1 9.1 0.1 2.7 2 0 0 2 2 2 0 Integrase core domain DNA_topoisoIV PF00521.20 CDJ67080.1 - 1.1e-113 380.3 0.0 1.7e-113 379.8 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CDJ67080.1 - 1.6e-23 83.4 3.5 5.2e-17 62.3 0.1 3.1 2 1 1 3 3 3 2 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CDJ67080.1 - 2.9e-20 72.5 0.3 6.2e-20 71.4 0.3 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CDJ67080.1 - 1.6e-10 41.5 0.1 5.4e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CDJ67080.1 - 1.8e-07 31.3 0.0 4.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Nucleoporin_FG PF13634.6 CDJ67081.1 - 6.9e-36 123.0 269.3 6.2e-10 39.8 39.7 9.7 3 2 7 10 10 10 9 Nucleoporin FG repeat region Ribosomal_S27 PF01599.19 CDJ67083.1 - 4.7e-26 90.7 2.8 9e-26 89.8 2.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 CDJ67083.1 - 6.5e-14 51.4 0.0 1.4e-13 50.4 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ67083.1 - 6e-06 26.0 0.0 2e-05 24.3 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ67083.1 - 0.0098 16.3 0.0 0.1 13.1 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 CDJ67083.1 - 0.024 14.7 0.4 0.091 12.8 0.0 2.1 3 1 0 3 3 3 0 Ubiquitin-like domain IBR PF01485.21 CDJ67083.1 - 0.034 14.4 0.9 0.056 13.7 0.9 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain EF_TS PF00889.19 CDJ67084.1 - 2.9e-27 95.6 0.1 3.2e-26 92.3 0.0 2.5 2 1 1 3 3 3 1 Elongation factor TS UBA_4 PF14555.6 CDJ67084.1 - 0.0092 15.8 0.3 0.12 12.2 0.1 2.4 2 0 0 2 2 2 1 UBA-like domain UBA PF00627.31 CDJ67084.1 - 0.011 15.6 0.2 0.031 14.2 0.2 1.8 1 0 0 1 1 1 0 UBA/TS-N domain SNase PF00565.17 CDJ67086.1 - 3.1e-10 40.5 0.0 0.18 12.3 0.0 4.7 4 1 0 4 4 4 3 Staphylococcal nuclease homologue TFIIA PF03153.13 CDJ67087.1 - 0.011 15.8 3.4 0.012 15.6 3.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2HC_2 PF13913.6 CDJ67088.1 - 1.6e-07 31.0 6.9 1.6e-07 31.0 6.9 1.7 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Transposase_21 PF02992.14 CDJ67088.1 - 0.64 9.2 2.9 3.1 7.0 2.9 2.2 1 0 0 1 1 1 0 Transposase family tnp2 ATG22 PF11700.8 CDJ67089.1 - 0.0013 17.5 0.0 0.0029 16.3 0.0 1.5 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF4637 PF15470.6 CDJ67089.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Mito_carr PF00153.27 CDJ67089.1 - 0.12 12.3 0.1 0.12 12.3 0.1 5.8 5 2 2 7 7 7 0 Mitochondrial carrier protein SARAF PF06682.12 CDJ67089.1 - 0.19 11.3 7.3 1.4 8.5 0.4 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SPX PF03105.19 CDJ67089.1 - 2.2 8.1 9.9 1 9.2 7.2 1.7 2 0 0 2 2 2 0 SPX domain Kinesin PF00225.23 CDJ67090.1 - 3.4e-42 144.5 0.0 3.4e-42 144.5 0.0 3.4 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ67090.1 - 5.5e-14 52.3 1.2 1.6e-08 34.6 0.0 3.8 4 0 0 4 4 4 2 Microtubule binding FHA PF00498.26 CDJ67090.1 - 5.1e-08 33.1 0.0 1.7e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 FHA domain Kinesin_assoc PF16183.5 CDJ67090.1 - 2e-05 24.8 0.2 2e-05 24.8 0.2 7.7 6 3 2 8 8 8 2 Kinesin-associated Yop-YscD_cpl PF16697.5 CDJ67090.1 - 0.057 13.7 0.0 1.9 8.9 0.0 3.0 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 CDJ67090.1 - 0.059 13.8 0.0 0.55 10.7 0.0 2.8 1 0 0 1 1 1 0 Kinesin protein 1B SRP_SPB PF02978.19 CDJ67091.1 - 0.0048 17.5 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Signal peptide binding domain DUF1679 PF07914.11 CDJ67091.1 - 0.16 10.8 0.2 0.25 10.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) TFIIA PF03153.13 CDJ67091.1 - 3.8 7.4 10.0 6.9 6.6 10.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRP-S27 PF10037.9 CDJ67094.1 - 0.39 9.5 6.2 0.49 9.2 6.2 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF2722 PF10846.8 CDJ67095.1 - 0.011 14.7 2.9 0.0098 14.9 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ67095.1 - 0.039 13.6 8.5 0.042 13.5 8.5 1.1 1 0 0 1 1 1 0 Spt20 family ANAPC_CDC26 PF10471.9 CDJ67095.1 - 0.042 14.7 8.4 0.06 14.2 8.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 FTZ PF03867.14 CDJ67095.1 - 0.16 11.5 5.1 0.18 11.3 5.1 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region TFIIA PF03153.13 CDJ67095.1 - 0.32 11.0 9.7 0.37 10.7 9.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0560 PF10577.9 CDJ67095.1 - 0.33 9.4 5.4 0.36 9.3 5.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SUIM_assoc PF16619.5 CDJ67095.1 - 0.6 10.2 12.4 0.96 9.6 12.4 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 YajC PF02699.15 CDJ67095.1 - 2 8.4 4.6 3.2 7.7 4.6 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Roughex PF06020.11 CDJ67095.1 - 2.4 7.2 5.9 2.3 7.2 5.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Kei1 PF08552.11 CDJ67095.1 - 2.6 7.9 5.0 3 7.7 5.0 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Radial_spoke PF04712.12 CDJ67097.1 - 1.5e-52 179.1 0.0 5.9e-30 104.7 0.1 4.2 2 1 1 3 3 3 3 Radial spokehead-like protein SUIM_assoc PF16619.5 CDJ67097.1 - 0.00017 21.6 16.2 0.00024 21.1 0.4 2.5 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ67097.1 - 0.41 9.5 10.6 2.7 6.8 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2722) M_domain PF12938.7 CDJ67097.1 - 2.2 8.0 24.1 3 7.6 11.0 2.4 2 0 0 2 2 2 0 M domain of GW182 TMEM208_SND2 PF05620.11 CDJ67097.1 - 3.3 7.4 4.0 4.4 7.1 0.1 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Pro-rich PF15240.6 CDJ67097.1 - 3.8 7.8 57.6 2.6 8.3 32.0 2.6 2 1 0 2 2 2 0 Proline-rich Collagen PF01391.18 CDJ67099.1 - 0.00036 20.2 39.1 0.00036 20.2 39.1 5.3 4 1 0 4 4 4 2 Collagen triple helix repeat (20 copies) FAST_1 PF06743.15 CDJ67100.1 - 0.0045 16.9 9.7 0.021 14.7 0.0 5.9 5 2 3 8 8 8 2 FAST kinase-like protein, subdomain 1 Ribonuc_P_40 PF08584.11 CDJ67101.1 - 3.2e-06 26.7 0.0 0.00022 20.6 0.0 2.3 2 1 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit AAA_23 PF13476.6 CDJ67102.1 - 1.5e-06 28.9 0.0 6e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 CDJ67102.1 - 3.5e-06 27.0 0.2 0.0068 16.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Metallophos PF00149.28 CDJ67102.1 - 1.9e-05 25.2 0.0 4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SMC_N PF02463.19 CDJ67102.1 - 0.0013 18.2 0.0 0.02 14.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CDJ67102.1 - 0.0013 18.9 0.0 0.0042 17.3 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit HTH_55 PF18622.1 CDJ67102.1 - 0.0047 17.2 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 RctB helix turn helix domain AAA_29 PF13555.6 CDJ67102.1 - 0.018 14.8 0.1 0.057 13.2 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain MukB PF04310.12 CDJ67102.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 MukB N-terminal TPR_2 PF07719.17 CDJ67103.1 - 2.2e-11 43.0 6.2 0.022 14.9 0.4 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ67103.1 - 1e-09 37.8 0.2 0.13 12.6 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ67103.1 - 2.6e-09 37.1 0.3 0.037 14.8 0.1 4.3 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ67103.1 - 3.6e-08 32.9 7.8 0.0076 16.0 0.3 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ67103.1 - 7.3e-08 32.5 0.7 0.00042 20.4 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ67103.1 - 2.4e-07 30.3 0.1 0.19 11.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ67103.1 - 1.2e-05 25.7 0.6 0.1 13.1 0.0 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ67103.1 - 7.3e-05 22.9 0.0 12 6.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ67103.1 - 0.00011 21.8 0.2 1.5 8.5 0.2 4.3 2 2 2 4 4 4 1 TPR repeat TPR_12 PF13424.6 CDJ67103.1 - 0.00018 21.8 0.9 1.6 9.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ67103.1 - 0.00048 20.6 0.2 3.7 8.4 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ67103.1 - 0.0011 19.6 2.3 0.057 14.1 0.2 3.7 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ67103.1 - 0.0027 17.0 0.0 0.0093 15.2 0.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ67103.1 - 0.0042 17.3 1.3 2 8.7 0.3 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF966 PF06136.13 CDJ67104.1 - 0.039 13.7 2.3 0.085 12.6 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TFIIA PF03153.13 CDJ67106.1 - 0.00097 19.2 18.0 0.0012 18.9 18.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 CDJ67106.1 - 0.57 9.0 5.7 0.69 8.7 5.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BAF1_ABF1 PF04684.13 CDJ67106.1 - 0.61 9.1 12.3 0.73 8.8 12.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Lin-8 PF03353.15 CDJ67106.1 - 0.8 9.2 8.0 1.2 8.6 8.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Herpes_LMP1 PF05297.11 CDJ67106.1 - 4.6 6.3 7.7 0.13 11.5 1.2 1.7 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) SAPS PF04499.15 CDJ67106.1 - 5.4 5.7 8.0 6.5 5.4 8.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4404 PF14357.6 CDJ67109.1 - 0.026 15.2 0.1 0.048 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) RskA PF10099.9 CDJ67109.1 - 0.043 14.1 15.4 3 8.1 0.0 2.9 1 1 1 2 2 2 0 Anti-sigma-K factor rskA TALPID3 PF15324.6 CDJ67109.1 - 1.7 6.2 4.9 2.4 5.7 4.9 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DEAD PF00270.29 CDJ67110.1 - 2.2e-10 40.6 8.4 6e-08 32.6 8.4 3.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CDJ67110.1 - 6.2e-09 36.4 4.9 6.2e-09 36.4 4.9 4.3 4 1 0 4 4 4 1 RecQ zinc-binding ResIII PF04851.15 CDJ67110.1 - 1.1e-07 32.1 3.1 5.5e-07 29.7 3.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ67110.1 - 0.0076 16.6 4.6 0.51 10.7 0.2 3.3 3 1 0 3 3 3 2 Helicase conserved C-terminal domain PA26 PF04636.13 CDJ67110.1 - 1.5 7.7 13.0 0.51 9.2 7.6 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) AAA_22 PF13401.6 CDJ67110.1 - 9.8 6.5 10.1 0.54 10.5 3.4 2.4 3 0 0 3 3 3 0 AAA domain 2-oxoacid_dh PF00198.23 CDJ67112.1 - 3.3e-43 147.8 0.0 5.7e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDJ67112.1 - 2.9e-19 68.6 0.7 4.9e-19 67.9 0.7 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CDJ67112.1 - 2.4e-16 59.8 1.0 1.5e-15 57.2 0.3 2.5 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CDJ67112.1 - 5.4e-08 32.5 0.0 1.7e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 CDJ67112.1 - 1.3e-06 27.8 0.0 2.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion PTS_EIIA_1 PF00358.20 CDJ67112.1 - 0.0089 15.8 0.0 0.044 13.6 0.0 2.0 1 1 1 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 GCV_H PF01597.19 CDJ67112.1 - 0.031 14.2 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF2722 PF10846.8 CDJ67113.1 - 0.0054 15.7 16.3 0.73 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TssC PF17541.2 CDJ67113.1 - 0.94 8.2 6.2 1.4 7.7 6.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB PhoQ_Sensor PF08918.10 CDJ67113.1 - 1.8 8.4 4.3 3.1 7.6 4.3 1.3 1 0 0 1 1 1 0 PhoQ Sensor TFIIA PF03153.13 CDJ67113.1 - 2.1 8.2 39.7 0.58 10.1 5.9 2.6 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Myc_N PF01056.18 CDJ67114.1 - 0.024 14.5 2.2 0.043 13.7 2.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Pox_Ag35 PF03286.14 CDJ67114.1 - 1.1 9.0 4.7 1.7 8.4 4.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3292 PF11696.8 CDJ67114.1 - 1.2 7.4 6.3 1.7 6.9 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) RNA_pol_3_Rpc31 PF11705.8 CDJ67114.1 - 1.4 9.1 6.1 2.1 8.5 6.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nbs1_C PF08599.10 CDJ67115.1 - 0.056 13.6 2.0 0.057 13.6 1.4 1.3 1 1 0 1 1 1 0 DNA damage repair protein Nbs1 GNAT_acetyltr_2 PF13718.6 CDJ67115.1 - 0.13 11.6 5.7 0.15 11.5 5.7 1.0 1 0 0 1 1 1 0 GNAT acetyltransferase 2 GerA PF03323.13 CDJ67115.1 - 0.28 9.6 3.7 0.31 9.5 3.7 1.0 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Activator_LAG-3 PF11498.8 CDJ67115.1 - 2.4 7.0 48.4 2.9 6.8 48.4 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Peptidase_M16 PF00675.20 CDJ67115.1 - 2.9 7.8 8.6 3.5 7.6 8.6 1.2 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) LCIB_C_CA PF18599.1 CDJ67115.1 - 8.8 5.6 9.3 10 5.4 9.3 1.0 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases SR-25 PF10500.9 CDJ67116.1 - 0.00035 20.3 1.4 0.00035 20.3 1.4 7.1 7 0 0 7 7 7 3 Nuclear RNA-splicing-associated protein DUF4834 PF16118.5 CDJ67116.1 - 0.017 16.1 39.9 5.4 8.0 1.0 7.8 7 0 0 7 7 7 0 Domain of unknown function (DUF4834) Chromo PF00385.24 CDJ67118.1 - 8.1e-15 54.5 0.0 1.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo PF00385.24 CDJ67119.1 - 4.2e-12 45.8 0.0 8e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain STI1 PF17830.1 CDJ67121.1 - 0.041 13.8 0.1 14 5.7 0.0 4.6 4 2 2 6 6 6 0 STI1 domain UBA PF00627.31 CDJ67121.1 - 5 7.1 11.4 2.7e+02 1.6 0.0 6.7 7 0 0 7 7 7 0 UBA/TS-N domain PAT1 PF09770.9 CDJ67123.1 - 8.2 4.6 30.0 11 4.2 30.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Helicase_C PF00271.31 CDJ67124.1 - 5.8e-11 42.7 0.0 2.6e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 CDJ67124.1 - 3.6e-09 36.9 0.1 3.6e-09 36.9 0.1 5.6 5 1 0 5 5 5 1 Helicase associated domain (HA2) BCS1_N PF08740.11 CDJ67125.1 - 7e-26 91.3 0.2 5.6e-25 88.4 0.0 2.0 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 CDJ67125.1 - 1.1e-12 48.5 0.0 3.8e-11 43.5 0.0 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ67125.1 - 0.00037 20.9 0.0 0.00037 20.9 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 CDJ67125.1 - 0.0026 17.6 10.3 0.049 13.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CDJ67125.1 - 0.017 14.7 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CDJ67125.1 - 0.02 14.8 0.3 0.046 13.6 0.0 1.7 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_33 PF13671.6 CDJ67125.1 - 0.046 13.9 0.0 0.046 13.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 CDJ67125.1 - 0.05 14.1 3.0 0.29 11.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 CDJ67125.1 - 0.066 12.9 0.7 6.2 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CDJ67125.1 - 0.076 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 CDJ67125.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ67125.1 - 0.091 12.8 0.5 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CLN3 PF02487.17 CDJ67125.1 - 0.14 11.2 4.1 11 4.9 4.8 2.1 2 0 0 2 2 2 0 CLN3 protein ATPase PF06745.13 CDJ67125.1 - 0.22 10.8 0.0 0.22 10.8 0.0 1.8 3 0 0 3 3 2 0 KaiC DUF3402 PF11882.8 CDJ67125.1 - 0.45 9.6 11.1 0.077 12.1 7.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) Hydin_ADK PF17213.3 CDJ67125.1 - 1.5 9.1 10.5 9.6 6.4 4.8 3.1 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain TFIIA PF03153.13 CDJ67125.1 - 2.5 8.0 32.0 7 6.5 0.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AAA_28 PF13521.6 CDJ67125.1 - 2.6 8.3 0.0 2.6 8.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain Neur_chan_memb PF02932.16 CDJ67125.1 - 3.5 7.6 7.4 5.1 7.1 5.5 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region AAA_23 PF13476.6 CDJ67125.1 - 6.8 7.1 16.7 50 4.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain Pribosyl_synth PF14572.6 CDJ67126.1 - 3.3e-08 33.8 0.3 3.6e-08 33.7 0.3 1.0 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Solute_trans_a PF03619.16 CDJ67127.1 - 4e-09 36.4 0.1 0.00039 20.0 0.0 2.2 2 0 0 2 2 2 2 Organic solute transporter Ostalpha Med15 PF09606.10 CDJ67128.1 - 0.012 14.3 41.6 0.015 14.0 41.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DDRGK PF09756.9 CDJ67128.1 - 0.017 14.7 21.4 0.022 14.3 21.4 1.1 1 0 0 1 1 1 0 DDRGK domain Apt1 PF10351.9 CDJ67128.1 - 0.022 13.6 16.6 0.025 13.4 16.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HemX PF04375.14 CDJ67128.1 - 0.023 14.0 30.1 0.033 13.5 30.1 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Lin-8 PF03353.15 CDJ67128.1 - 0.043 13.4 25.4 0.061 12.9 25.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Fmp27_WPPW PF10359.9 CDJ67128.1 - 0.083 11.7 23.3 0.1 11.4 23.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Miga PF10265.9 CDJ67128.1 - 0.098 11.6 14.2 0.13 11.2 14.2 1.3 1 0 0 1 1 1 0 Mitoguardin DUF4683 PF15735.5 CDJ67128.1 - 0.11 12.1 14.6 0.12 11.9 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) Exonuc_VII_L PF02601.15 CDJ67128.1 - 0.17 11.5 17.4 0.23 11.0 17.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_S49_N PF08496.10 CDJ67128.1 - 0.23 11.5 14.9 0.34 10.9 14.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4746 PF15928.5 CDJ67128.1 - 0.41 10.0 9.2 0.51 9.7 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SPX PF03105.19 CDJ67128.1 - 0.43 10.4 23.6 0.53 10.2 23.6 1.2 1 0 0 1 1 1 0 SPX domain Peptidase_S64 PF08192.11 CDJ67128.1 - 0.45 8.9 20.6 0.56 8.6 20.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 CDJ67128.1 - 0.98 6.5 28.5 1.2 6.2 28.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF572 PF04502.13 CDJ67128.1 - 1 8.9 22.8 1.4 8.5 22.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3584 PF12128.8 CDJ67128.1 - 1 6.8 24.7 1.2 6.5 24.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PAT1 PF09770.9 CDJ67128.1 - 1.2 7.3 32.7 1.5 7.0 32.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WASH-7_C PF14746.6 CDJ67128.1 - 1.3 8.7 16.9 2.3 7.9 16.9 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Sin_N PF04801.13 CDJ67128.1 - 1.4 8.1 26.2 1.6 7.9 26.2 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region DUF2232 PF09991.9 CDJ67128.1 - 1.4 8.0 3.4 1.9 7.6 3.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Asp-B-Hydro_N PF05279.11 CDJ67128.1 - 1.9 8.5 13.2 2.2 8.3 13.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2203 PF09969.9 CDJ67128.1 - 1.9 9.2 13.0 4.2 8.1 13.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ALMT PF11744.8 CDJ67128.1 - 2.2 7.0 15.1 2.9 6.6 15.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Cellulose_synt PF03552.14 CDJ67128.1 - 2.3 6.6 7.4 2.6 6.4 7.4 1.1 1 0 0 1 1 1 0 Cellulose synthase Membralin PF09746.9 CDJ67128.1 - 2.4 7.1 10.1 2.8 6.9 10.1 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF2151 PF10221.9 CDJ67128.1 - 2.5 6.6 13.7 3 6.3 13.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator FAM220 PF15487.6 CDJ67128.1 - 2.7 7.5 18.4 3.4 7.2 18.4 1.2 1 0 0 1 1 1 0 FAM220 family V_ATPase_I PF01496.19 CDJ67128.1 - 2.9 5.7 17.9 3.8 5.3 17.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ureide_permease PF07168.11 CDJ67128.1 - 2.9 6.6 7.0 5.7 5.6 7.0 1.5 1 0 0 1 1 1 0 Ureide permease eIF-3_zeta PF05091.12 CDJ67128.1 - 3.9 6.4 19.2 5 6.0 19.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SRP-alpha_N PF04086.13 CDJ67128.1 - 4.3 7.2 23.6 5.3 6.9 23.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Plasmodium_Vir PF05795.11 CDJ67128.1 - 4.4 6.6 15.7 5.7 6.3 15.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mcm10 PF09332.11 CDJ67128.1 - 4.7 6.6 26.0 5.9 6.2 26.0 1.2 1 0 0 1 1 1 0 Mcm10 replication factor EMC3_TMCO1 PF01956.16 CDJ67128.1 - 4.8 6.9 12.6 7 6.3 12.6 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2828 PF11443.8 CDJ67128.1 - 5.5 4.9 17.4 7.9 4.4 17.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Folate_carrier PF01770.18 CDJ67128.1 - 5.7 5.6 10.7 8.6 5.0 10.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier SLC12 PF03522.15 CDJ67128.1 - 5.8 5.8 20.9 7.3 5.5 20.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 CDJ67128.1 - 5.8 5.6 15.6 7.6 5.2 15.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MMR1 PF08505.10 CDJ67128.1 - 6.9 6.9 25.9 9.6 6.4 25.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein XRN_M PF17846.1 CDJ67128.1 - 6.9 5.5 12.2 8.3 5.2 12.2 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF4407 PF14362.6 CDJ67128.1 - 7.1 5.9 26.1 1.4 8.2 20.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HSD3 PF15244.6 CDJ67128.1 - 7.2 6.0 24.8 9.1 5.7 24.8 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 DUF4446 PF14584.6 CDJ67128.1 - 8.6 6.3 8.3 13 5.8 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2126 PF09899.9 CDJ67128.1 - 8.8 4.2 14.0 12 3.8 14.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) MAT1 PF06391.13 CDJ67128.1 - 9.2 6.0 24.6 13 5.6 24.6 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 KOW PF00467.29 CDJ67130.1 - 0.00025 20.9 0.1 0.00037 20.3 0.1 1.2 1 0 0 1 1 1 1 KOW motif SH3_2 PF07653.17 CDJ67130.1 - 0.068 12.9 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain MazE_antitoxin PF04014.18 CDJ67130.1 - 0.084 12.8 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin Peptidase_S8 PF00082.22 CDJ67131.1 - 3.5e-22 79.0 0.2 4.4e-22 78.7 0.2 1.1 1 0 0 1 1 1 1 Subtilase family NIL PF09383.10 CDJ67131.1 - 0.19 11.6 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 NIL domain FAM199X PF15814.5 CDJ67132.1 - 0.069 12.2 17.4 0.091 11.8 17.4 1.1 1 0 0 1 1 1 0 Protein family FAM199X Mod_r PF07200.13 CDJ67132.1 - 0.086 12.9 16.0 0.14 12.3 16.0 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF2126 PF09899.9 CDJ67132.1 - 0.18 9.9 4.8 0.22 9.6 4.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DcuA_DcuB PF03605.14 CDJ67132.1 - 0.46 9.3 7.4 0.6 9.0 7.4 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter SR-25 PF10500.9 CDJ67132.1 - 0.47 10.0 12.4 0.69 9.5 12.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4712 PF15830.5 CDJ67132.1 - 0.71 9.5 9.8 0.92 9.1 9.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) Mucin PF01456.17 CDJ67132.1 - 0.72 9.8 15.9 2.5 8.1 15.9 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein TFIIA PF03153.13 CDJ67132.1 - 1.6 8.6 37.1 2.5 8.0 37.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S46 PF10459.9 CDJ67132.1 - 1.7 7.2 16.4 2.1 6.9 16.4 1.0 1 0 0 1 1 1 0 Peptidase S46 AAA_23 PF13476.6 CDJ67132.1 - 2 8.8 11.7 2.4 8.6 11.7 1.2 1 0 0 1 1 1 0 AAA domain ATC_hydrolase PF14196.6 CDJ67132.1 - 2.3 9.0 6.0 3.4 8.4 6.0 1.2 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase SRP-alpha_N PF04086.13 CDJ67132.1 - 6.1 6.7 15.6 8.9 6.1 15.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SID-1_RNA_chan PF13965.6 CDJ67133.1 - 0.0055 15.2 7.0 0.0066 14.9 0.7 2.2 2 0 0 2 2 2 2 dsRNA-gated channel SID-1 Cadherin_C_2 PF16492.5 CDJ67133.1 - 0.0065 17.2 8.6 0.047 14.4 1.9 3.4 2 1 0 2 2 2 1 Cadherin cytoplasmic C-terminal HRG PF16954.5 CDJ67133.1 - 0.015 15.7 0.5 0.041 14.3 0.5 1.7 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene TLP-20 PF06088.11 CDJ67133.1 - 0.02 14.8 0.2 0.02 14.8 0.2 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SARAF PF06682.12 CDJ67133.1 - 0.75 9.4 14.4 2.3e+02 1.2 14.4 2.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CSG2 PF16965.5 CDJ67133.1 - 1 8.2 15.0 0.047 12.6 1.5 2.5 2 1 1 3 3 3 0 Ceramide synthase regulator TAP35_44 PF07265.11 CDJ67133.1 - 2.4 8.2 7.4 2.1 8.4 5.0 2.0 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 DUF3446 PF11928.8 CDJ67133.1 - 4.1 7.8 16.4 0.37 11.1 9.0 2.6 2 1 0 2 2 2 0 Early growth response N-terminal domain RskA PF10099.9 CDJ67134.1 - 2.6e-06 27.9 9.8 2.6e-06 27.9 9.8 5.8 5 1 0 5 5 4 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ67134.1 - 3e-05 23.2 13.5 0.0015 17.6 7.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ67134.1 - 0.00079 19.5 11.5 0.00079 19.5 11.5 2.7 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ67134.1 - 0.001 18.7 25.9 0.097 12.3 0.6 2.3 2 0 0 2 2 2 2 Spt20 family Velvet PF11754.8 CDJ67134.1 - 0.0017 18.3 0.2 0.0032 17.5 0.2 1.4 1 0 0 1 1 1 1 Velvet factor WD40 PF00400.32 CDJ67134.1 - 0.0034 18.2 3.3 11 7.1 0.0 4.9 6 0 0 6 6 4 0 WD domain, G-beta repeat IHABP4_N PF16174.5 CDJ67134.1 - 0.012 16.2 6.7 0.012 16.2 6.7 4.1 5 0 0 5 5 4 0 Intracellular hyaluronan-binding protein 4 N-terminal SUIM_assoc PF16619.5 CDJ67134.1 - 0.013 15.6 1.7 0.013 15.6 1.7 3.9 3 1 0 3 3 1 0 Unstructured region C-term to UIM in Ataxin3 SRP9-21 PF05486.12 CDJ67134.1 - 0.016 15.6 3.4 0.15 12.4 0.7 3.2 3 0 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) DUF5521 PF17659.1 CDJ67134.1 - 0.046 11.6 7.4 0.075 10.9 7.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) FHIPEP PF00771.20 CDJ67134.1 - 0.089 11.2 6.9 0.032 12.7 4.0 1.6 2 0 0 2 2 2 0 FHIPEP family DUF966 PF06136.13 CDJ67134.1 - 0.12 12.1 5.9 0.2 11.3 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CTU2 PF10288.9 CDJ67134.1 - 1.9 8.7 17.3 0.092 13.0 9.5 2.6 3 0 0 3 3 2 0 Cytoplasmic tRNA 2-thiolation protein 2 SprA-related PF12118.8 CDJ67134.1 - 2.2 7.4 26.0 0.022 13.9 13.0 2.5 2 0 0 2 2 2 0 SprA-related family Suf PF05843.14 CDJ67134.1 - 3.6 7.5 13.7 0.68 9.9 6.2 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3371 PF11851.8 CDJ67134.1 - 3.9 8.6 10.4 2 9.5 3.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) MAGE PF01454.19 CDJ67134.1 - 4.9 6.8 7.6 19 4.9 0.0 2.7 3 0 0 3 3 3 0 MAGE family DUF4770 PF15994.5 CDJ67134.1 - 5.3 7.2 10.2 9.7 6.4 3.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) R_equi_Vir PF05526.11 CDJ67134.1 - 5.4 6.8 8.8 23 4.8 8.8 2.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein EPL1 PF10513.9 CDJ67134.1 - 8.7 6.7 8.4 1.8 8.9 2.4 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF4834 PF16118.5 CDJ67134.1 - 9.2 7.3 13.3 11 7.1 6.4 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) Mob1_phocein PF03637.17 CDJ67135.1 - 4.6e-12 46.3 0.0 2e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Mob1/phocein family Asp-B-Hydro_N PF05279.11 CDJ67135.1 - 2 8.5 24.2 0.21 11.6 4.1 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region CCSAP PF15748.5 CDJ67135.1 - 7.4 6.7 27.4 0.6 10.2 14.0 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated EIF_2_alpha PF07541.12 CDJ67136.1 - 1e-20 73.9 2.3 4.7e-20 71.8 0.8 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit Herpes_BLLF1 PF05109.13 CDJ67136.1 - 0.0068 14.5 5.3 0.0083 14.2 5.3 1.0 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) SNAP PF14938.6 CDJ67136.1 - 0.31 10.4 3.1 0.31 10.4 2.2 1.4 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Borrelia_P83 PF05262.11 CDJ67136.1 - 0.33 9.4 6.8 0.33 9.4 6.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein YtxH PF12732.7 CDJ67136.1 - 0.93 10.1 6.6 5.7 7.6 6.6 2.4 1 1 0 1 1 1 0 YtxH-like protein Ndc1_Nup PF09531.10 CDJ67136.1 - 4.8 5.7 4.4 5.8 5.5 4.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Med13_C PF06333.12 CDJ67136.1 - 6.9 5.8 8.0 9.4 5.4 8.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain PP1_bind PF15276.6 CDJ67136.1 - 8.3 6.8 10.8 1.2e+03 -0.1 10.8 3.3 1 1 0 1 1 1 0 Protein phosphatase 1 binding TFIIF_alpha PF05793.12 CDJ67137.1 - 0.59 8.7 26.5 0.65 8.5 26.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.9 CDJ67137.1 - 1.3 7.5 25.1 1.4 7.4 25.1 1.0 1 0 0 1 1 1 0 Macoilin family Plasmodium_Vir PF05795.11 CDJ67137.1 - 2.7 7.3 22.3 3.2 7.1 22.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NAM-associated PF14303.6 CDJ67138.1 - 0.00083 20.1 0.0 0.00083 20.1 0.0 5.5 1 1 2 4 4 4 1 No apical meristem-associated C-terminal domain SR-25 PF10500.9 CDJ67138.1 - 0.0075 15.9 25.4 0.0075 15.9 25.4 5.9 3 2 2 5 5 5 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ67138.1 - 0.0084 16.4 5.8 0.0084 16.4 5.8 4.8 3 2 2 5 5 5 3 Anti-sigma-K factor rskA SDA1 PF05285.12 CDJ67138.1 - 0.13 11.6 44.9 0.008 15.7 18.9 2.2 2 0 0 2 2 2 0 SDA1 Miga PF10265.9 CDJ67139.1 - 0.059 12.3 3.2 0.058 12.4 3.2 1.0 1 0 0 1 1 1 0 Mitoguardin Trp_oprn_chp PF09534.10 CDJ67139.1 - 0.073 12.9 12.1 0.078 12.8 12.1 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.6 CDJ67139.1 - 0.13 13.2 0.2 0.15 13.0 0.2 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4179 PF13786.6 CDJ67139.1 - 0.38 11.2 2.9 0.49 10.9 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Shadoo PF14999.6 CDJ67139.1 - 0.75 9.9 12.8 0.81 9.8 12.8 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective LapA_dom PF06305.11 CDJ67139.1 - 1.1 9.2 5.4 1.4 8.8 5.4 1.3 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3682 PF12446.8 CDJ67139.1 - 2.1 8.8 17.3 2.6 8.5 17.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) RskA PF10099.9 CDJ67139.1 - 4.7 7.5 24.0 6.7 7.0 24.0 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA AP2 PF00847.20 CDJ67141.1 - 2.1e-14 53.4 1.6 2.1e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.6 CDJ67141.1 - 6.1e-13 48.9 0.0 6.1e-13 48.9 0.0 2.1 2 1 1 3 3 3 1 AP2-coincident C-terminal CENP-T_C PF15511.6 CDJ67143.1 - 6.1e-09 36.0 0.1 7.3e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CDJ67143.1 - 0.00023 21.3 0.0 0.0003 20.9 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CDJ67143.1 - 0.00051 20.4 0.1 0.00073 19.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CDJ67143.1 - 0.00055 20.2 0.0 0.00079 19.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ67143.1 - 0.0013 19.1 0.1 0.0015 18.9 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CDJ67143.1 - 0.023 14.8 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CDJ67143.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 CDJ67143.1 - 0.066 13.0 0.2 0.081 12.7 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TAFII28 PF04719.14 CDJ67143.1 - 0.069 13.2 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Spt20 PF12090.8 CDJ67144.1 - 0.0029 17.3 2.2 0.007 16.0 2.2 1.7 1 0 0 1 1 1 1 Spt20 family Tic22 PF04278.12 CDJ67144.1 - 0.078 12.4 1.5 3.7 6.8 0.2 2.9 2 2 0 2 2 2 0 Tic22-like family RNF111_N PF15303.6 CDJ67144.1 - 0.45 10.3 7.2 2.7 7.7 0.1 3.0 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus Ribosomal_60s PF00428.19 CDJ67144.1 - 6.6 7.4 53.3 6.5 7.4 6.5 4.7 4 0 0 4 4 4 0 60s Acidic ribosomal protein SUIM_assoc PF16619.5 CDJ67144.1 - 7.7 6.7 18.2 29 4.8 16.3 2.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-CCCH_4 PF18044.1 CDJ67145.1 - 8.6e-06 25.4 0.5 8.6e-06 25.4 0.5 3.4 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ67145.1 - 5.4e-05 23.0 1.0 5.4e-05 23.0 1.0 3.7 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CDJ67145.1 - 0.24 12.0 11.8 3.8 8.1 0.0 4.2 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger IMUP PF15761.5 CDJ67146.1 - 0.1 13.3 7.6 0.13 13.0 7.6 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ67146.1 - 0.26 10.9 9.4 0.28 10.8 9.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DNA_pol_E_B PF04042.16 CDJ67147.1 - 2.4e-11 43.4 0.5 1.6e-09 37.4 0.2 2.3 1 1 1 2 2 2 2 DNA polymerase alpha/epsilon subunit B eIF3_subunit PF08597.10 CDJ67147.1 - 2.2 8.1 6.0 1.2 9.0 0.5 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit PRP38_assoc PF12871.7 CDJ67148.1 - 1.6 9.4 17.9 0.16 12.6 13.2 1.7 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Ion_trans_2 PF07885.16 CDJ67149.1 - 4.6e-12 45.7 0.4 1.4e-11 44.2 0.4 1.9 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CDJ67149.1 - 0.012 14.8 6.7 0.019 14.2 6.7 1.2 1 0 0 1 1 1 0 Ion transport protein IATP PF04568.12 CDJ67149.1 - 0.13 12.7 0.1 0.13 12.7 0.1 3.2 4 1 0 4 4 4 0 Mitochondrial ATPase inhibitor, IATP TFIIA PF03153.13 CDJ67149.1 - 6.3 6.7 15.6 14 5.5 8.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DcpS_C PF11969.8 CDJ67151.1 - 1e-05 26.0 0.0 0.0061 17.0 0.0 2.9 3 0 0 3 3 3 2 Scavenger mRNA decapping enzyme C-term binding Apt1 PF10351.9 CDJ67151.1 - 0.11 11.3 7.3 0.16 10.8 7.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Histone PF00125.24 CDJ67151.1 - 1.2 9.5 3.6 2.3 8.6 1.7 2.2 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TFIIF_alpha PF05793.12 CDJ67151.1 - 10 4.6 6.7 14 4.1 6.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1635 PF07795.11 CDJ67152.1 - 0.061 13.2 9.1 0.1 12.5 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Vfa1 PF08432.10 CDJ67152.1 - 0.11 12.9 9.2 0.19 12.1 9.2 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PI3K_1B_p101 PF10486.9 CDJ67152.1 - 0.21 9.3 13.6 0.34 8.6 13.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Peptidase_S64 PF08192.11 CDJ67152.1 - 0.37 9.2 7.5 0.51 8.8 7.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Lin-8 PF03353.15 CDJ67152.1 - 0.41 10.2 8.9 0.73 9.3 8.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ67152.1 - 0.86 8.4 14.0 1.1 8.1 14.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAP1 PF08601.10 CDJ67152.1 - 1.3 8.6 18.6 1.9 8.2 18.6 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Neur_chan_memb PF02932.16 CDJ67152.1 - 2.8 7.9 4.2 3.8 7.5 4.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rrn6 PF10214.9 CDJ67152.1 - 3.4 6.0 14.5 4 5.8 14.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MPM1 PF17234.2 CDJ67152.1 - 4.3 7.6 10.7 7.6 6.8 10.7 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Sec62 PF03839.16 CDJ67152.1 - 6.2 6.3 6.8 9 5.7 6.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF755 PF05501.11 CDJ67152.1 - 7.2 6.9 32.2 0.49 10.7 27.1 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF755) SOG2 PF10428.9 CDJ67153.1 - 0.11 11.6 32.8 0.13 11.4 32.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4551 PF15087.6 CDJ67153.1 - 1.6 7.4 31.0 1.9 7.2 31.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PAT1 PF09770.9 CDJ67153.1 - 6.1 5.0 61.2 7 4.8 61.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dicty_REP PF05086.12 CDJ67153.1 - 6.3 4.6 18.6 7.9 4.3 18.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ThiJ_like PF17124.5 CDJ67154.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 ThiJ/PfpI family-like Nuc_sug_transp PF04142.15 CDJ67155.1 - 3e-105 351.9 7.5 3.6e-105 351.6 7.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.6 CDJ67155.1 - 8.8e-06 25.5 6.0 0.00018 21.2 6.0 2.2 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter CRT-like PF08627.10 CDJ67155.1 - 1.1e-05 24.5 1.5 2.3e-05 23.5 1.5 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 CDJ67155.1 - 2.5e-05 23.6 10.0 6.4e-05 22.3 6.0 2.5 2 1 0 2 2 2 1 UAA transporter family EamA PF00892.20 CDJ67155.1 - 3.6e-05 24.0 31.4 0.00085 19.5 8.2 2.8 2 1 1 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 CDJ67155.1 - 0.0002 20.7 1.8 0.00041 19.7 1.8 1.5 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 CDJ67155.1 - 0.083 12.2 9.5 0.048 13.0 1.5 2.9 2 1 0 2 2 2 0 Triose-phosphate Transporter family ENOD93 PF03386.14 CDJ67155.1 - 0.46 10.4 5.6 1.3 8.9 0.0 3.0 3 0 0 3 3 3 0 Early nodulin 93 ENOD93 protein LCCL PF03815.19 CDJ67157.1 - 1.8e-31 108.1 0.3 2.5e-16 59.6 0.0 2.3 1 1 1 2 2 2 2 LCCL domain Ribosomal_L32e PF01655.18 CDJ67159.1 - 9.2e-45 151.5 0.2 1.2e-44 151.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 pPIWI_RE_X PF13111.6 CDJ67159.1 - 0.064 12.4 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 pPIWI_RE module N-terminal domain CDP-OH_P_transf PF01066.21 CDJ67160.1 - 2.4e-14 53.8 0.1 2.4e-14 53.8 0.1 3.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PNP_UDP_1 PF01048.20 CDJ67161.1 - 4.3e-31 108.0 0.2 1.1e-30 106.7 0.0 1.7 2 0 0 2 2 2 1 Phosphorylase superfamily Paf1 PF03985.13 CDJ67162.1 - 0.025 13.6 15.0 0.023 13.7 15.0 1.2 1 0 0 1 1 1 0 Paf1 DcuA_DcuB PF03605.14 CDJ67162.1 - 0.026 13.4 11.3 0.033 13.1 11.3 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Glyco_transf_41 PF13844.6 CDJ67162.1 - 0.031 12.7 9.1 0.032 12.7 9.1 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 SID-1_RNA_chan PF13965.6 CDJ67162.1 - 0.061 11.7 5.7 0.06 11.8 5.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF-3_zeta PF05091.12 CDJ67162.1 - 0.063 12.3 24.6 0.06 12.3 24.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2828 PF11443.8 CDJ67162.1 - 0.25 9.4 15.8 0.24 9.5 15.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 CDJ67162.1 - 0.27 10.2 11.5 0.29 10.1 11.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CDJ67162.1 - 0.32 10.8 19.9 0.36 10.6 19.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ67162.1 - 0.41 9.6 16.8 0.37 9.8 16.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Velvet PF11754.8 CDJ67162.1 - 0.41 10.5 18.9 0.44 10.4 18.9 1.2 1 0 0 1 1 1 0 Velvet factor TFIIA PF03153.13 CDJ67162.1 - 0.43 10.5 56.5 0.48 10.4 56.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.15 CDJ67162.1 - 0.48 9.3 10.9 0.49 9.3 10.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) V_ATPase_I PF01496.19 CDJ67162.1 - 0.48 8.3 17.5 0.46 8.4 17.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SprA-related PF12118.8 CDJ67162.1 - 0.54 9.3 45.2 0.76 8.8 45.2 1.2 1 0 0 1 1 1 0 SprA-related family FAM60A PF15396.6 CDJ67162.1 - 0.58 10.1 14.4 0.63 10.0 14.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.16 CDJ67162.1 - 0.67 10.0 13.7 0.67 10.0 13.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CSG2 PF16965.5 CDJ67162.1 - 0.95 8.3 9.6 0.89 8.4 9.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator CD20 PF04103.15 CDJ67162.1 - 1 9.4 6.1 0.25 11.4 1.8 1.8 1 1 1 2 2 2 0 CD20-like family AAA_23 PF13476.6 CDJ67162.1 - 1.1 9.7 19.5 1.4 9.4 19.5 1.3 1 0 0 1 1 1 0 AAA domain TCP PF03634.13 CDJ67162.1 - 1.2 9.7 23.8 1.4 9.5 23.8 1.2 1 0 0 1 1 1 0 TCP family transcription factor PAT1 PF09770.9 CDJ67162.1 - 1.2 7.3 36.5 1.3 7.2 36.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NEMP PF10225.9 CDJ67162.1 - 1.3 8.6 9.4 1.5 8.4 9.4 1.1 1 0 0 1 1 1 0 NEMP family Bul1_N PF04425.12 CDJ67162.1 - 1.5 7.5 15.6 1.6 7.4 15.6 1.0 1 0 0 1 1 1 0 Bul1 N terminus ALMT PF11744.8 CDJ67162.1 - 2 7.1 14.8 1.9 7.2 14.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MAJIN PF15077.6 CDJ67162.1 - 2.1 8.1 11.7 2 8.2 11.7 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Tim54 PF11711.8 CDJ67162.1 - 2.9 6.6 17.3 3.9 6.1 17.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RIFIN PF02009.16 CDJ67162.1 - 3 7.7 25.0 3.8 7.3 25.0 1.2 1 0 0 1 1 1 0 Rifin MDM10 PF12519.8 CDJ67162.1 - 3.2 6.5 17.1 3.3 6.5 17.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SpoIIP PF07454.11 CDJ67162.1 - 3.3 7.1 22.2 4.1 6.8 22.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) HCO3_cotransp PF00955.21 CDJ67162.1 - 4.1 6.1 8.6 4 6.2 8.6 1.1 1 0 0 1 1 1 0 HCO3- transporter family Myc_N PF01056.18 CDJ67162.1 - 4.9 7.0 16.9 6.1 6.6 16.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Hid1 PF12722.7 CDJ67162.1 - 5.3 5.0 18.8 4.8 5.2 18.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1682 PF07946.14 CDJ67162.1 - 7 5.8 17.6 6.9 5.8 17.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HAUS6_N PF14661.6 CDJ67162.1 - 7.1 6.1 24.7 8.2 5.9 24.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Peptidase_S15 PF02129.18 CDJ67162.1 - 7.2 6.1 22.3 9.5 5.7 22.3 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Connexin PF00029.19 CDJ67162.1 - 7.3 6.3 17.6 8.8 6.0 17.6 1.1 1 0 0 1 1 1 0 Connexin Rav1p_C PF12234.8 CDJ67164.1 - 1.6e-22 79.7 19.6 4.2e-17 61.8 0.5 5.2 6 0 0 6 6 6 3 RAVE protein 1 C terminal PspB PF06667.12 CDJ67166.1 - 0.016 15.2 0.2 0.022 14.8 0.2 1.3 1 0 0 1 1 1 0 Phage shock protein B Spt20 PF12090.8 CDJ67166.1 - 0.16 11.6 9.8 0.15 11.6 9.8 1.2 1 0 0 1 1 1 0 Spt20 family CcmD PF04995.14 CDJ67166.1 - 0.23 11.6 3.6 0.61 10.2 3.5 1.8 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) TFIIA PF03153.13 CDJ67166.1 - 0.55 10.2 11.4 0.58 10.1 11.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3306 PF11748.8 CDJ67168.1 - 0.31 11.9 15.3 0.59 11.0 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) SPX PF03105.19 CDJ67168.1 - 0.6 10.0 9.7 0.54 10.1 6.0 2.1 2 0 0 2 2 2 0 SPX domain DUF1387 PF07139.11 CDJ67168.1 - 3.6 7.2 11.9 0.42 10.3 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Herpes_pp85 PF04637.12 CDJ67168.1 - 4.4 5.6 6.0 6.9 5.0 6.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CNDH2_M PF16869.5 CDJ67168.1 - 4.5 8.0 13.7 13 6.5 2.9 2.7 2 0 0 2 2 2 0 PF16858 Surface_antigen PF11054.8 CDJ67169.1 - 3.2e-31 108.9 1.2 3.9e-31 108.6 1.2 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Asp_protease PF09668.10 CDJ67170.1 - 5.9e-48 161.7 0.0 1.1e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ67170.1 - 5.9e-18 65.2 0.2 1.9e-17 63.6 0.0 2.0 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 CDJ67170.1 - 3.2e-09 36.4 1.9 3.9e-09 36.1 0.0 2.1 2 0 0 2 2 1 1 Ubiquitin family Asp_protease_2 PF13650.6 CDJ67170.1 - 2.7e-07 31.1 0.0 8.3e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDJ67170.1 - 0.00022 21.0 0.2 0.0011 18.7 0.2 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 CDJ67170.1 - 0.00077 19.2 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.20 CDJ67170.1 - 0.0027 18.0 0.1 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Spt20 PF12090.8 CDJ67170.1 - 0.012 15.2 9.3 0.012 15.2 9.3 2.3 2 0 0 2 2 2 0 Spt20 family DUF4179 PF13786.6 CDJ67170.1 - 0.026 15.0 1.3 3.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Pex14_N PF04695.13 CDJ67170.1 - 0.029 15.0 9.9 0.57 10.8 3.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.10 CDJ67170.1 - 0.048 12.4 23.4 0.063 12.0 23.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.6 CDJ67170.1 - 0.051 12.8 4.3 0.091 12.0 0.8 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2722 PF10846.8 CDJ67170.1 - 0.42 9.5 12.9 0.34 9.8 9.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) CPSF73-100_C PF11718.8 CDJ67170.1 - 0.92 9.0 3.7 0.3 10.6 0.3 1.9 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term CCDC53 PF10152.9 CDJ67170.1 - 1.5 9.2 8.6 10 6.5 3.7 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TetR_C_9 PF14514.6 CDJ67170.1 - 2.8 8.1 4.6 1.7 8.8 0.3 2.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain CPSF100_C PF13299.6 CDJ67170.1 - 3.7 7.7 6.8 5.1 7.2 4.0 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Neuregulin PF02158.15 CDJ67170.1 - 4 6.7 8.9 0.21 10.9 3.4 1.6 2 0 0 2 2 2 0 Neuregulin intracellular region IHABP4_N PF16174.5 CDJ67170.1 - 8.3 7.0 16.4 7.9 7.0 2.0 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4834 PF16118.5 CDJ67170.1 - 9 7.3 8.2 0.5 11.3 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DEAD PF00270.29 CDJ67171.1 - 3.3e-09 36.7 0.1 3e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase SUIM_assoc PF16619.5 CDJ67171.1 - 0.028 14.5 4.8 0.028 14.5 4.8 4.8 3 2 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ67171.1 - 0.088 12.8 38.8 0.49 10.3 7.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ67171.1 - 0.11 12.4 15.1 0.43 10.4 6.8 2.1 2 0 0 2 2 2 0 SPX domain ATPase_2 PF01637.18 CDJ67171.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MDM31_MDM32 PF08118.11 CDJ67171.1 - 7.9 5.0 5.1 2.1 6.9 0.3 2.1 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins HECT PF00632.25 CDJ67172.1 - 1.9e-69 234.5 0.0 3.4e-69 233.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 CDJ67172.1 - 7.6e-36 122.5 7.1 2.6e-09 37.5 0.0 7.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ67172.1 - 8e-20 70.1 20.3 8.8e-06 25.4 0.1 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat R_equi_Vir PF05526.11 CDJ67172.1 - 1.5 8.7 7.7 0.65 9.8 0.0 3.4 3 0 0 3 3 3 0 Rhodococcus equi virulence-associated protein tRNA-synt_1c PF00749.21 CDJ67173.1 - 2.2e-100 335.6 0.0 2.2e-100 335.6 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CDJ67173.1 - 3e-47 160.7 0.0 7.4e-47 159.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain MFS_1 PF07690.16 CDJ67174.1 - 8.7e-13 47.9 21.2 1.8e-11 43.6 21.9 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily FAM176 PF14851.6 CDJ67174.1 - 0.00061 19.5 0.2 0.088 12.5 0.3 2.4 2 0 0 2 2 2 1 FAM176 family LapA_dom PF06305.11 CDJ67174.1 - 0.0025 17.6 0.7 0.29 11.0 0.1 2.8 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Connexin PF00029.19 CDJ67174.1 - 0.0031 17.3 1.2 0.0037 17.1 0.0 1.7 2 0 0 2 2 2 1 Connexin Peptidase_U4 PF03419.13 CDJ67174.1 - 0.0063 15.8 4.5 0.013 14.8 0.6 2.5 2 0 0 2 2 2 1 Sporulation factor SpoIIGA MAS20 PF02064.15 CDJ67174.1 - 0.0071 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 MAS20 protein import receptor DUF2681 PF10883.8 CDJ67174.1 - 0.0087 16.4 0.6 0.33 11.4 0.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) DUF1043 PF06295.12 CDJ67174.1 - 0.041 13.9 0.4 0.082 12.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) MAP17 PF15807.5 CDJ67174.1 - 0.049 13.9 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Involucrin2 PF06994.11 CDJ67174.1 - 0.11 12.6 11.5 0.18 11.9 11.5 1.4 1 0 0 1 1 1 0 Involucrin DUF4500 PF14937.6 CDJ67174.1 - 0.19 11.8 0.1 5.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) DUF2040 PF09745.9 CDJ67175.1 - 1.6e-16 60.5 24.3 7.4e-15 55.1 7.6 2.9 3 0 0 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) XRN_N PF03159.18 CDJ67176.1 - 3e-53 180.8 0.0 1.2e-45 155.8 0.0 3.1 3 1 0 3 3 3 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CDJ67176.1 - 1.9e-42 145.8 1.0 9e-27 94.1 0.9 4.4 5 0 0 5 5 5 2 Xrn1 helical domain PLRV_ORF5 PF01690.17 CDJ67176.1 - 0.081 11.6 0.2 0.18 10.5 0.2 1.5 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Aldo_ket_red PF00248.21 CDJ67177.1 - 1.1e-47 162.6 0.0 6.6e-43 147.0 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family DUF4054 PF13262.6 CDJ67177.1 - 0.77 9.8 4.4 0.77 9.8 2.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4054) PP2C PF00481.21 CDJ67178.1 - 2.5e-19 69.9 0.1 7.1e-16 58.6 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SUIM_assoc PF16619.5 CDJ67178.1 - 0.014 15.5 3.0 0.014 15.5 3.0 3.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SPX PF03105.19 CDJ67178.1 - 0.026 14.4 5.5 0.068 13.1 5.5 1.6 1 1 0 1 1 1 0 SPX domain SR-25 PF10500.9 CDJ67178.1 - 0.25 10.9 19.8 0.036 13.7 13.2 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4834 PF16118.5 CDJ67178.1 - 1.2 10.1 3.5 0.78 10.7 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PPR_2 PF13041.6 CDJ67179.1 - 1.3e-08 34.9 0.1 2.9e-07 30.6 0.0 2.3 1 1 1 2 2 2 1 PPR repeat family PPR_long PF17177.4 CDJ67179.1 - 2.2e-07 30.5 0.2 3e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CDJ67179.1 - 0.00012 22.1 0.1 0.0078 16.3 0.0 1.8 1 1 1 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 CDJ67179.1 - 0.0075 16.5 0.2 0.38 11.1 0.0 2.7 2 1 0 2 2 2 1 PPR repeat PPR_1 PF12854.7 CDJ67179.1 - 0.11 12.3 0.1 5.3 6.8 0.0 2.6 3 0 0 3 3 3 0 PPR repeat LpxK PF02606.14 CDJ67181.1 - 0.14 11.2 0.5 0.17 10.9 0.5 1.0 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Thioredoxin_4 PF13462.6 CDJ67181.1 - 0.3 11.3 1.7 0.46 10.6 1.7 1.3 1 0 0 1 1 1 0 Thioredoxin Zip PF02535.22 CDJ67182.1 - 0.44 9.7 1.8 0.78 8.9 1.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter zf-CCHC_2 PF13696.6 CDJ67183.1 - 1.6e-07 31.0 4.1 3.9e-07 29.8 4.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CDJ67183.1 - 0.0086 16.1 5.2 0.022 14.8 5.2 1.8 1 0 0 1 1 1 1 Zinc knuckle SUIM_assoc PF16619.5 CDJ67183.1 - 0.093 12.8 0.0 0.093 12.8 0.0 4.0 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 zf-CCHC_4 PF14392.6 CDJ67183.1 - 0.17 11.6 2.8 0.4 10.5 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle SR-25 PF10500.9 CDJ67184.1 - 0.0023 17.6 17.4 0.0031 17.2 17.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ67184.1 - 0.16 11.9 18.9 0.21 11.6 18.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ67184.1 - 0.19 9.8 19.4 0.22 9.6 19.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein K_channel_TID PF07941.11 CDJ67184.1 - 0.23 11.9 0.3 0.23 11.9 0.3 2.7 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain DUF3402 PF11882.8 CDJ67184.1 - 0.28 10.2 4.3 0.35 9.9 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) CCDC106 PF15794.5 CDJ67184.1 - 0.34 10.6 10.2 0.39 10.4 10.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 GREB1 PF15782.5 CDJ67184.1 - 1 6.4 10.4 1 6.4 10.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 CDJ67184.1 - 1.3 7.8 10.4 1.4 7.7 10.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.15 CDJ67184.1 - 3.2 7.2 12.5 4.2 6.8 12.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ67184.1 - 8.4 4.8 9.7 10 4.5 9.7 1.1 1 0 0 1 1 1 0 Macoilin family Ras PF00071.22 CDJ67185.1 - 2.3e-36 124.8 9.0 1.7e-18 66.8 5.1 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CDJ67185.1 - 1.4e-26 93.0 9.8 4e-14 52.9 6.8 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ67185.1 - 1.2e-07 31.3 2.3 1.4e-05 24.7 0.8 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family TFIIA PF03153.13 CDJ67185.1 - 0.0015 18.6 15.7 0.0015 18.6 15.7 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit RNA_pol_Rpc4 PF05132.14 CDJ67185.1 - 0.0062 17.0 1.2 0.057 13.8 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase III RPC4 DUF2722 PF10846.8 CDJ67185.1 - 0.0098 14.9 16.1 0.0098 14.9 16.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) SpoIIP PF07454.11 CDJ67185.1 - 0.014 14.9 1.0 0.014 14.9 1.0 1.4 2 0 0 2 2 1 0 Stage II sporulation protein P (SpoIIP) FHIPEP PF00771.20 CDJ67185.1 - 0.026 13.0 6.1 0.035 12.6 6.1 1.1 1 0 0 1 1 1 0 FHIPEP family Pex14_N PF04695.13 CDJ67185.1 - 0.028 15.1 9.1 0.028 15.1 9.1 2.8 3 1 1 4 4 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PduV-EutP PF10662.9 CDJ67185.1 - 0.036 13.8 0.0 0.17 11.7 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 CDJ67185.1 - 0.054 13.6 0.1 8.1 6.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DcuA_DcuB PF03605.14 CDJ67185.1 - 0.059 12.3 4.6 0.081 11.8 4.6 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter AAA_22 PF13401.6 CDJ67185.1 - 0.059 13.6 0.4 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Presenilin PF01080.17 CDJ67185.1 - 0.063 12.0 3.9 0.15 10.8 2.4 1.9 2 0 0 2 2 2 0 Presenilin AAA_29 PF13555.6 CDJ67185.1 - 0.063 13.0 0.0 0.24 11.2 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1980 PF09323.10 CDJ67185.1 - 0.098 12.6 1.0 0.24 11.3 0.6 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF1980) CSG2 PF16965.5 CDJ67185.1 - 0.1 11.6 0.8 0.19 10.7 0.8 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator RsgA_GTPase PF03193.16 CDJ67185.1 - 0.1 12.5 2.1 0.25 11.3 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase DUF4667 PF15700.5 CDJ67185.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.6 2 1 0 2 2 1 0 Domain of unknown function (DUF4667) AAA_5 PF07728.14 CDJ67185.1 - 0.16 11.9 0.2 0.36 10.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) Hpr_kinase_C PF07475.12 CDJ67185.1 - 0.2 11.1 1.5 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_24 PF13479.6 CDJ67185.1 - 0.21 11.3 1.3 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain CPSF100_C PF13299.6 CDJ67185.1 - 0.33 11.1 5.2 0.11 12.7 1.4 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Ribosomal_60s PF00428.19 CDJ67185.1 - 0.93 10.1 39.0 0.23 12.1 13.0 3.4 3 0 0 3 3 2 0 60s Acidic ribosomal protein ABC_tran PF00005.27 CDJ67185.1 - 1.7 9.2 0.0 1.7 9.2 0.0 2.8 3 0 0 3 3 3 0 ABC transporter AIF_C PF14721.6 CDJ67185.1 - 2.3 8.6 8.2 0.25 11.7 2.9 1.9 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Suf PF05843.14 CDJ67185.1 - 2.9 7.8 16.6 9.5 6.1 12.7 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Senescence_reg PF04520.13 CDJ67185.1 - 4.8 8.0 9.2 1.2 10.0 1.5 2.3 2 0 0 2 2 2 0 Senescence regulator GREB1 PF15782.5 CDJ67185.1 - 6 3.9 13.1 0.89 6.6 0.3 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer DUF4179 PF13786.6 CDJ67185.1 - 8.5 6.9 15.7 4.5 7.8 3.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Spt20 PF12090.8 CDJ67185.1 - 9.2 5.8 35.0 5.5 6.5 28.4 2.1 2 0 0 2 2 2 0 Spt20 family PH PF00169.29 CDJ67187.1 - 0.096 13.2 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 PH domain K_channel_TID PF07941.11 CDJ67188.1 - 0.036 14.5 4.3 0.036 14.5 4.3 3.6 3 1 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain DUF5435 PF17503.2 CDJ67188.1 - 0.12 12.1 0.2 0.16 11.7 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Dehydratase_MU PF02288.15 CDJ67188.1 - 0.18 11.7 7.5 0.32 10.9 7.5 1.5 1 1 0 1 1 1 0 Dehydratase medium subunit TFIIA PF03153.13 CDJ67188.1 - 0.27 11.2 9.1 0.31 11.0 9.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sedlin_N PF04628.13 CDJ67189.1 - 4.2e-12 46.3 0.0 5.6e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CDJ67189.1 - 0.018 15.0 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 Sybindin-like family Apt1 PF10351.9 CDJ67190.1 - 0.91 8.3 4.0 1.2 7.9 4.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain BRCT_2 PF16589.5 CDJ67191.1 - 1.4e-06 28.6 0.0 4.3e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CDJ67191.1 - 7.4 6.5 9.8 22 5.0 0.0 4.4 4 0 0 4 4 4 0 Regulator of Ty1 transposition protein 107 BRCT domain Fibrillin_U_N PF18193.1 CDJ67192.1 - 1.5 9.0 9.1 15 5.8 0.1 4.6 2 2 3 5 5 5 0 Fibrillin 1 unique N-terminal domain Enolase_C PF00113.22 CDJ67195.1 - 3.5e-142 473.0 0.0 5.4e-142 472.3 0.0 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CDJ67195.1 - 1.4e-49 167.6 0.1 1.4e-49 167.6 0.1 2.8 2 0 0 2 2 1 1 Enolase, N-terminal domain DUF3645 PF12359.8 CDJ67195.1 - 1.2e-15 56.6 0.1 2.4e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) MR_MLE_C PF13378.6 CDJ67195.1 - 2.2e-11 43.7 0.1 2e-10 40.6 0.0 2.6 2 1 0 2 2 2 1 Enolase C-terminal domain-like EF-hand_7 PF13499.6 CDJ67195.1 - 2.6e-05 24.6 0.1 8.7e-05 22.9 0.0 1.9 2 0 0 2 2 1 1 EF-hand domain pair MAAL_C PF07476.11 CDJ67195.1 - 7.7e-05 22.0 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus EF-hand_6 PF13405.6 CDJ67195.1 - 8.8e-05 22.1 0.4 0.67 10.0 0.1 3.2 3 0 0 3 3 2 2 EF-hand domain EF-hand_1 PF00036.32 CDJ67195.1 - 0.00027 20.3 0.1 0.0088 15.5 0.1 2.5 2 0 0 2 2 2 1 EF hand RskA PF10099.9 CDJ67195.1 - 0.0011 19.3 8.1 0.0011 19.3 8.1 12.1 8 4 2 11 11 6 2 Anti-sigma-K factor rskA EF-hand_8 PF13833.6 CDJ67195.1 - 0.0042 16.9 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Vps62 PF06101.11 CDJ67195.1 - 0.17 10.1 0.0 0.29 9.4 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 Arg_decarbox_C PF17944.1 CDJ67195.1 - 0.78 10.3 3.9 26 5.5 0.1 4.1 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension SR-25 PF10500.9 CDJ67195.1 - 2.1 7.9 38.5 0.084 12.5 2.4 3.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein tRNA_synthFbeta PF17759.1 CDJ67196.1 - 2.1e-31 109.0 0.0 4.3e-31 108.0 0.0 1.5 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 CDJ67196.1 - 2.4e-10 40.6 0.0 5.5e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase B5 domain B3_4 PF03483.17 CDJ67196.1 - 2.8e-06 27.1 0.2 8.8e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 B3/4 domain SUIM_assoc PF16619.5 CDJ67196.1 - 0.047 13.8 7.8 0.098 12.7 7.8 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Adaptin_N PF01602.20 CDJ67196.1 - 0.071 11.7 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region DUF4805 PF16063.5 CDJ67196.1 - 0.08 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) RNA_pol_Rpc4 PF05132.14 CDJ67196.1 - 0.092 13.2 1.4 0.18 12.2 1.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Med3 PF11593.8 CDJ67196.1 - 0.59 9.3 5.2 0.88 8.7 5.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 CDJ67196.1 - 4.7 6.7 8.8 7.5 6.1 8.8 1.2 1 0 0 1 1 1 0 Spt20 family Spt20 PF12090.8 CDJ67197.1 - 2.2 7.8 9.4 2.4 7.7 9.4 1.1 1 0 0 1 1 1 0 Spt20 family DUF755 PF05501.11 CDJ67198.1 - 2.3 8.5 8.6 0.59 10.4 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ67198.1 - 2.3 7.7 11.9 4.8 6.7 1.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Clat_adaptor_s PF01217.20 CDJ67199.1 - 1.8e-44 151.1 1.2 2e-44 151.0 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.25 CDJ67200.1 - 5e-49 167.0 0.3 6.1e-49 166.7 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ67200.1 - 3.1e-29 102.1 0.2 4e-29 101.7 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ67200.1 - 0.0002 21.3 0.0 0.015 15.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ67200.1 - 0.0016 17.9 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SmAKAP PF15127.6 CDJ67200.1 - 0.011 16.9 0.5 0.028 15.6 0.5 1.7 2 0 0 2 2 2 0 Small membrane A-kinase anchor protein Pkinase_fungal PF17667.1 CDJ67200.1 - 0.019 13.7 0.3 0.027 13.2 0.3 1.3 1 1 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 CDJ67200.1 - 0.034 13.5 0.1 0.93 8.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like RRM_1 PF00076.22 CDJ67201.1 - 5.1e-21 74.3 0.1 7.7e-21 73.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 CDJ67201.1 - 2.4e-14 53.7 4.9 2.4e-14 53.7 4.9 2.7 3 0 0 3 3 3 2 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CDJ67202.1 - 5.4e-26 90.2 0.0 2e-16 59.6 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ67202.1 - 0.1 12.7 0.0 1 9.5 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif RRM_occluded PF16842.5 CDJ67202.1 - 1.2 9.1 3.8 58 3.6 0.0 3.8 4 1 0 4 4 4 0 Occluded RNA-recognition motif TraT PF05818.12 CDJ67205.1 - 0.00015 21.5 9.9 0.00018 21.2 9.9 1.0 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein RskA PF10099.9 CDJ67205.1 - 0.00045 20.6 16.4 0.00056 20.3 16.4 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ67205.1 - 0.0064 16.1 31.8 0.0064 16.1 31.8 1.0 1 0 0 1 1 1 1 Spt20 family Shadoo PF14999.6 CDJ67205.1 - 0.013 15.6 3.9 0.014 15.5 3.9 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF2681 PF10883.8 CDJ67205.1 - 0.026 14.9 19.0 0.033 14.6 19.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4834 PF16118.5 CDJ67205.1 - 0.074 14.0 13.6 0.084 13.9 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) N6_N4_Mtase PF01555.18 CDJ67205.1 - 0.13 12.0 1.8 0.13 12.0 1.8 1.0 1 0 0 1 1 1 0 DNA methylase Cid2 PF09774.9 CDJ67205.1 - 0.14 12.6 12.7 0.15 12.5 12.7 1.1 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DUF2722 PF10846.8 CDJ67205.1 - 0.21 10.5 30.2 0.23 10.3 30.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ67205.1 - 0.28 10.1 32.6 0.28 10.1 32.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 eIF-3_zeta PF05091.12 CDJ67205.1 - 0.29 10.0 15.4 0.28 10.1 15.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FHIPEP PF00771.20 CDJ67205.1 - 0.3 9.5 5.9 0.31 9.5 5.9 1.0 1 0 0 1 1 1 0 FHIPEP family Suf PF05843.14 CDJ67205.1 - 0.31 11.0 14.6 0.32 10.9 14.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Porin_4 PF13609.6 CDJ67205.1 - 0.37 10.5 6.7 0.42 10.3 6.7 1.1 1 0 0 1 1 1 0 Gram-negative porin TFIIA PF03153.13 CDJ67205.1 - 0.38 10.7 32.7 0.41 10.6 32.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ67205.1 - 0.39 9.3 28.5 0.42 9.2 28.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal WBP-1 PF11669.8 CDJ67205.1 - 0.4 11.3 4.7 0.55 10.9 4.7 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF819 PF05684.12 CDJ67205.1 - 0.42 9.6 1.8 0.5 9.4 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF819) Connexin PF00029.19 CDJ67205.1 - 0.45 10.2 6.4 0.44 10.3 6.4 1.1 1 0 0 1 1 1 0 Connexin DUF1980 PF09323.10 CDJ67205.1 - 0.51 10.2 5.2 0.5 10.3 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Ureide_permease PF07168.11 CDJ67205.1 - 0.54 9.0 3.7 0.65 8.7 3.7 1.2 1 0 0 1 1 1 0 Ureide permease TERB2 PF15101.6 CDJ67205.1 - 0.58 10.2 15.7 0.56 10.2 15.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 HA2 PF04408.23 CDJ67205.1 - 0.64 10.3 5.1 0.83 10.0 5.1 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) Peroxin-13_N PF04088.13 CDJ67205.1 - 0.66 10.3 5.7 0.72 10.1 5.7 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Coilin_N PF15862.5 CDJ67205.1 - 0.68 9.7 12.2 0.82 9.5 12.2 1.2 1 0 0 1 1 1 0 Coilin N-terminus FAM176 PF14851.6 CDJ67205.1 - 0.7 9.5 9.2 0.86 9.3 9.2 1.1 1 0 0 1 1 1 0 FAM176 family SID-1_RNA_chan PF13965.6 CDJ67205.1 - 0.79 8.1 2.2 0.71 8.2 2.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF775 PF05603.12 CDJ67205.1 - 0.82 9.2 12.2 0.9 9.0 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Wzz PF02706.15 CDJ67205.1 - 0.83 10.0 6.1 1.3 9.4 6.1 1.3 1 0 0 1 1 1 0 Chain length determinant protein V_ATPase_I PF01496.19 CDJ67205.1 - 0.85 7.5 9.7 0.74 7.7 9.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cellulose_synt PF03552.14 CDJ67205.1 - 0.89 8.0 4.8 0.86 8.0 4.8 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF2232 PF09991.9 CDJ67205.1 - 0.92 8.6 2.0 1.1 8.4 2.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Ctr PF04145.15 CDJ67205.1 - 0.96 10.1 6.8 0.99 10.0 6.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family THOC2_N PF16134.5 CDJ67205.1 - 0.96 8.0 10.0 1.1 7.8 10.0 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus SpoIIP PF07454.11 CDJ67205.1 - 0.97 8.8 11.6 0.98 8.8 11.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Band_3_cyto PF07565.13 CDJ67205.1 - 1 9.1 9.2 1 9.1 9.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain R_equi_Vir PF05526.11 CDJ67205.1 - 1.1 9.1 9.8 1.2 8.9 9.8 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Bac_luciferase PF00296.20 CDJ67205.1 - 1.1 8.6 11.2 1.1 8.6 11.2 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase TFB6 PF17110.5 CDJ67205.1 - 1.2 8.9 7.5 1.3 8.7 7.5 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RR_TM4-6 PF06459.12 CDJ67205.1 - 1.2 8.9 10.0 1.2 8.9 10.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ67205.1 - 1.5 7.5 13.7 1.4 7.6 13.7 1.0 1 0 0 1 1 1 0 Presenilin DUF3537 PF12056.8 CDJ67205.1 - 1.7 7.4 12.0 1.9 7.2 12.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DDHD PF02862.17 CDJ67205.1 - 1.8 8.7 10.3 1.7 8.8 10.3 1.1 1 0 0 1 1 1 0 DDHD domain EOS1 PF12326.8 CDJ67205.1 - 1.8 8.5 5.5 1.9 8.4 5.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein DREPP PF05558.12 CDJ67205.1 - 1.8 8.4 6.4 1.9 8.3 6.4 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide UPF0560 PF10577.9 CDJ67205.1 - 2.3 6.6 18.7 2.1 6.8 18.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Neur_chan_memb PF02932.16 CDJ67205.1 - 2.3 8.2 7.6 2.3 8.2 7.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ67205.1 - 2.8 6.9 6.5 2.5 7.1 6.5 1.1 1 0 0 1 1 1 0 CLN3 protein CSG2 PF16965.5 CDJ67205.1 - 3.2 6.6 4.4 3 6.7 4.4 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator FAM199X PF15814.5 CDJ67205.1 - 3.7 6.5 11.1 4 6.4 11.1 1.0 1 0 0 1 1 1 0 Protein family FAM199X ALMT PF11744.8 CDJ67205.1 - 4.1 6.1 7.4 3.8 6.2 7.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 CDJ67205.1 - 4.7 6.3 5.0 5 6.3 5.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 CDJ67205.1 - 5.6 5.8 7.2 5.2 5.9 7.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) PBP_sp32 PF07222.12 CDJ67205.1 - 5.7 6.3 14.3 5.2 6.5 14.3 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TALPID3 PF15324.6 CDJ67205.1 - 6.2 4.4 18.0 7.2 4.1 18.0 1.0 1 0 0 1 1 1 0 Hedgehog signalling target PigN PF04987.14 CDJ67205.1 - 7.9 5.2 5.0 7.6 5.3 5.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) SR-25 PF10500.9 CDJ67206.1 - 0.0077 15.9 26.7 0.0077 15.9 26.7 3.2 2 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein Trp_oprn_chp PF09534.10 CDJ67206.1 - 0.098 12.5 56.5 0.25 11.1 56.5 1.7 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PAT1 PF09770.9 CDJ67206.1 - 9 4.4 27.8 11 4.2 27.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_30 PF13604.6 CDJ67207.1 - 0.0003 20.6 0.8 0.0003 20.6 0.8 3.5 2 1 2 4 4 3 1 AAA domain AAA_16 PF13191.6 CDJ67207.1 - 0.00034 21.0 0.2 0.00034 21.0 0.2 2.6 1 1 1 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 CDJ67207.1 - 0.0011 18.7 0.0 0.0029 17.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.22 CDJ67207.1 - 0.0022 17.2 0.1 0.0028 16.9 0.1 1.1 1 0 0 1 1 1 1 NB-ARC domain ATP_bind_1 PF03029.17 CDJ67207.1 - 0.0089 15.8 0.4 0.012 15.4 0.4 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein cobW PF02492.19 CDJ67207.1 - 0.014 15.0 0.3 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CDJ67207.1 - 0.015 15.2 0.3 0.025 14.5 0.3 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 CDJ67207.1 - 0.016 15.7 0.3 0.024 15.2 0.3 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ67207.1 - 0.021 14.1 0.1 0.039 13.2 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 CDJ67207.1 - 0.023 13.7 0.1 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 CDJ67207.1 - 0.042 13.8 0.1 0.063 13.3 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 CDJ67207.1 - 0.048 13.6 0.3 0.067 13.1 0.3 1.2 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.18 CDJ67207.1 - 0.053 13.2 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CDJ67207.1 - 0.055 13.7 0.1 0.094 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CDJ67207.1 - 0.067 13.4 0.3 0.067 13.4 0.3 2.2 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 CDJ67207.1 - 0.19 12.2 0.2 0.31 11.5 0.1 1.4 2 0 0 2 2 1 0 AAA domain G-alpha PF00503.20 CDJ67207.1 - 0.29 10.2 0.0 0.38 9.9 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Filament_head PF04732.14 CDJ67207.1 - 0.68 10.8 17.6 2.8 8.9 10.6 2.4 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Spt20 PF12090.8 CDJ67207.1 - 2.9 7.4 5.9 4 7.0 5.9 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ67207.1 - 5.2 7.0 15.8 6.2 6.7 15.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S4 PF00163.19 CDJ67209.1 - 3.4e-06 27.9 3.8 3.4e-06 27.9 3.8 2.1 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 CDJ67209.1 - 0.042 13.6 1.6 0.41 10.4 0.4 2.3 2 0 0 2 2 2 0 S4 domain SNARE PF05739.19 CDJ67209.1 - 3 7.9 5.8 6.5 6.8 5.8 1.5 1 0 0 1 1 1 0 SNARE domain YqzE PF14038.6 CDJ67209.1 - 4.5 7.4 10.1 11 6.1 10.1 1.6 1 0 0 1 1 1 0 YqzE-like protein Ribosomal_S28e PF01200.18 CDJ67210.1 - 1.4e-31 108.3 1.5 1.5e-31 108.2 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e SNF2_N PF00176.23 CDJ67211.1 - 1.3e-29 103.1 12.2 2.9e-29 101.9 12.2 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 CDJ67211.1 - 0.002 18.1 11.1 0.0069 16.4 11.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Nha1_C PF08619.10 CDJ67211.1 - 0.0057 15.9 15.8 0.0057 15.9 15.8 3.4 3 2 0 3 3 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus Otopetrin PF03189.13 CDJ67211.1 - 0.037 12.9 1.8 0.37 9.6 0.3 2.2 2 0 0 2 2 2 0 Otopetrin Tim54 PF11711.8 CDJ67211.1 - 0.098 11.4 12.4 0.28 9.9 12.4 1.8 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Apt1 PF10351.9 CDJ67211.1 - 0.31 9.9 14.6 0.3 9.9 9.2 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain AAA_11 PF13086.6 CDJ67211.1 - 0.36 10.6 17.9 0.16 11.7 14.2 2.1 2 0 0 2 2 2 0 AAA domain DUF913 PF06025.12 CDJ67211.1 - 1.1 8.1 14.3 0.17 10.8 9.8 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CDJ67211.1 - 1.2 7.8 29.2 0.038 12.7 19.9 2.3 2 1 0 2 2 2 0 Presenilin ABC2_membrane_2 PF12679.7 CDJ67211.1 - 1.5 8.0 5.5 0.69 9.1 0.6 2.6 3 0 0 3 3 3 0 ABC-2 family transporter protein Band_3_cyto PF07565.13 CDJ67211.1 - 2.2 8.0 20.3 0.36 10.6 14.2 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2151 PF10221.9 CDJ67211.1 - 2.5 6.6 15.4 4.1 5.9 15.4 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator V_ATPase_I PF01496.19 CDJ67211.1 - 2.8 5.7 17.0 5.1 4.9 17.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 CDJ67211.1 - 3 6.6 14.9 5.2 5.8 14.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter CDK5_activator PF03261.15 CDJ67211.1 - 3.3 7.2 12.8 6.7 6.2 12.8 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Raftlin PF15250.6 CDJ67211.1 - 3.6 6.2 15.8 8.4 5.0 15.8 1.5 1 0 0 1 1 1 0 Raftlin Zip PF02535.22 CDJ67211.1 - 4.6 6.4 14.1 9.2 5.4 14.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4407 PF14362.6 CDJ67211.1 - 5.9 6.1 26.9 3 7.1 18.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SfLAP PF11139.8 CDJ67213.1 - 0.037 13.5 1.0 0.047 13.1 1.0 1.2 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein TFIIF_alpha PF05793.12 CDJ67214.1 - 0.0019 16.9 18.6 0.0032 16.2 18.6 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF755 PF05501.11 CDJ67214.1 - 0.0047 17.2 43.7 0.0047 17.2 43.7 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF755) Apt1 PF10351.9 CDJ67214.1 - 0.034 13.0 17.6 0.039 12.8 17.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM60A PF15396.6 CDJ67214.1 - 0.044 13.8 20.2 0.016 15.2 17.7 1.5 2 0 0 2 2 2 0 Protein Family FAM60A DUF4746 PF15928.5 CDJ67214.1 - 0.18 11.2 4.4 0.26 10.7 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SRP-alpha_N PF04086.13 CDJ67214.1 - 0.53 10.2 21.4 0.65 9.9 21.4 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4603 PF15376.6 CDJ67214.1 - 1.2 6.5 21.5 1.4 6.2 21.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF4551 PF15087.6 CDJ67214.1 - 1.3 7.8 16.4 1.2 7.9 16.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Menin PF05053.13 CDJ67214.1 - 1.4 7.2 14.8 1.6 7.0 14.8 1.1 1 0 0 1 1 1 0 Menin GREB1 PF15782.5 CDJ67214.1 - 2.1 5.4 17.6 2.2 5.3 17.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 CDJ67214.1 - 3 6.0 19.1 4.1 5.6 19.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.11 CDJ67214.1 - 3.4 6.0 18.4 4.9 5.5 18.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 FancD2 PF14631.6 CDJ67214.1 - 6.9 3.9 15.0 9.6 3.5 15.0 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SR-25 PF10500.9 CDJ67215.1 - 9.2 5.8 20.0 12 5.4 20.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HEAT PF02985.22 CDJ67216.1 - 4.3 7.9 8.5 64 4.2 0.4 6.0 3 0 0 3 3 3 0 HEAT repeat SID-1_RNA_chan PF13965.6 CDJ67216.1 - 6.2 5.1 14.5 7.6 4.8 0.2 3.0 2 1 0 2 2 2 0 dsRNA-gated channel SID-1 Spt20 PF12090.8 CDJ67218.1 - 0.013 15.1 2.9 0.018 14.6 2.9 1.2 1 0 0 1 1 1 0 Spt20 family DUF3801 PF12687.7 CDJ67218.1 - 0.42 10.7 9.7 0.59 10.2 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) HMG_box PF00505.19 CDJ67219.1 - 5.1e-12 46.0 2.4 5.1e-12 46.0 2.4 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ67219.1 - 0.00017 22.1 1.6 0.00017 22.1 1.6 3.1 2 1 1 3 3 3 1 HMG-box domain ubiquitin PF00240.23 CDJ67220.1 - 3.8e-58 193.2 2.9 1.4e-34 117.6 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CDJ67220.1 - 4.2e-27 93.8 2.0 1.9e-16 59.6 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ67220.1 - 7.2e-10 39.2 0.5 2.6e-05 24.6 0.1 3.3 2 2 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ67220.1 - 4.7e-07 29.9 0.0 0.018 15.2 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CDJ67220.1 - 7.2e-07 29.5 0.1 0.014 15.8 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ67220.1 - 1.9e-06 27.7 0.2 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 CDJ67220.1 - 4.4e-05 24.0 0.1 0.1 13.1 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CDJ67220.1 - 0.00029 20.8 2.6 6.6 6.9 0.0 3.1 3 0 0 3 3 3 3 Ubiquitin-like domain DUF2870 PF11069.8 CDJ67220.1 - 0.008 16.5 0.0 8 6.9 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF2870) Sde2_N_Ubi PF13019.6 CDJ67220.1 - 0.043 13.7 0.1 0.56 10.0 0.0 2.0 1 1 1 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain FERM_f0 PF16511.5 CDJ67220.1 - 0.094 13.0 0.5 22 5.4 0.2 2.9 2 1 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM DUF969 PF06149.12 CDJ67220.1 - 0.098 12.1 0.0 4.9 6.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF969) Yip1 PF04893.17 CDJ67221.1 - 0.0046 16.7 0.5 0.007 16.1 0.5 1.3 1 0 0 1 1 1 1 Yip1 domain 7tm_1 PF00001.21 CDJ67221.1 - 0.0058 16.0 0.2 0.0064 15.8 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MatE PF01554.18 CDJ67221.1 - 0.0067 16.1 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 MatE PHO4 PF01384.20 CDJ67221.1 - 0.031 13.3 2.7 2.6 7.0 0.0 2.3 1 1 0 2 2 2 0 Phosphate transporter family Herpes_UL25 PF01499.16 CDJ67221.1 - 0.087 11.3 0.1 0.1 11.1 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family SLC3A2_N PF16028.5 CDJ67221.1 - 0.44 10.1 8.0 1.7 8.3 1.1 2.2 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus TssO PF17561.2 CDJ67221.1 - 1.1 9.4 6.4 0.54 10.4 1.1 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssO Halogen_Hydrol PF10112.9 CDJ67221.1 - 1.8 8.5 3.6 0.62 10.1 0.2 1.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein LapA_dom PF06305.11 CDJ67221.1 - 7.7 6.4 6.7 0.3 10.9 0.8 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SAD_SRA PF02182.17 CDJ67223.1 - 0.083 12.6 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 SAD/SRA domain DUF126 PF01989.16 CDJ67224.1 - 0.12 12.1 0.2 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Aconitase X swivel domain PH_TFIIH PF08567.11 CDJ67226.1 - 0.13 12.6 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Pkinase PF00069.25 CDJ67228.1 - 0.0047 16.3 0.0 0.0081 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ67228.1 - 0.055 12.7 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Sec63 PF02889.16 CDJ67229.1 - 5e-57 193.0 0.2 1.1e-56 191.9 0.2 1.5 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 CDJ67229.1 - 1.7e-25 89.8 0.0 4.2e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CDJ67229.1 - 7e-23 80.9 0.3 2.1e-22 79.4 0.3 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 CDJ67229.1 - 6.8e-14 52.2 0.6 2.3e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ67229.1 - 9.1e-09 35.6 0.0 8.6e-08 32.5 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ67229.1 - 0.086 13.1 0.1 0.58 10.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain PHC2_SAM_assoc PF16616.5 CDJ67229.1 - 1.9 9.3 6.0 5.7 7.8 6.0 1.8 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Sec63 PF02889.16 CDJ67230.1 - 5.4e-45 153.6 0.0 9.7e-36 123.2 0.0 3.3 3 0 0 3 3 3 3 Sec63 Brl domain DEAD PF00270.29 CDJ67230.1 - 1.1e-13 51.3 0.0 2.1e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ67230.1 - 5.5e-06 26.7 0.0 2e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dehydrin PF00257.19 CDJ67231.1 - 1.7 9.2 4.6 0.41 11.2 1.3 1.8 2 0 0 2 2 2 0 Dehydrin DUF4578 PF15147.6 CDJ67233.1 - 0.047 14.6 0.1 0.084 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Mce4_CUP1 PF11887.8 CDJ67233.1 - 0.62 9.5 6.1 1.1 8.6 5.2 1.7 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative RVP_2 PF08284.11 CDJ67235.1 - 2.7e-08 33.7 0.0 4.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ67235.1 - 1.1e-07 32.3 0.0 1.9e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ67235.1 - 1.5e-07 32.0 0.0 3.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CDJ67235.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ67235.1 - 0.011 16.1 0.0 0.037 14.3 0.0 2.0 2 1 0 2 2 2 0 Retroviral aspartyl protease zf-CCHC PF00098.23 CDJ67236.1 - 0.00012 22.0 15.0 0.0021 18.0 3.9 3.6 5 0 0 5 5 5 2 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ67236.1 - 0.002 17.9 0.6 0.002 17.9 0.6 3.4 4 0 0 4 4 4 1 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ67236.1 - 0.007 16.1 0.9 0.007 16.1 0.9 2.6 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger DnaJ_CXXCXGXG PF00684.19 CDJ67236.1 - 0.026 14.9 2.7 0.059 13.8 2.7 1.5 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_3 PF13917.6 CDJ67236.1 - 0.077 13.0 5.6 0.1 12.6 0.3 2.4 1 1 1 2 2 2 0 Zinc knuckle DUF5594 PF18057.1 CDJ67236.1 - 0.11 12.3 1.6 6.9 6.5 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5594) Retrotrans_gag PF03732.17 CDJ67236.1 - 0.14 12.4 0.1 0.64 10.3 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2722 PF10846.8 CDJ67237.1 - 0.00025 20.1 3.7 0.00032 19.8 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ67237.1 - 0.0012 19.0 14.1 0.0014 18.8 14.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ67237.1 - 0.014 15.0 14.6 0.019 14.6 14.6 1.1 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ67237.1 - 0.27 11.2 7.6 0.35 10.8 7.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hamartin PF04388.12 CDJ67237.1 - 0.48 9.0 6.9 0.64 8.6 6.9 1.1 1 0 0 1 1 1 0 Hamartin protein PAT1 PF09770.9 CDJ67237.1 - 0.9 7.7 7.8 1.1 7.5 7.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4834 PF16118.5 CDJ67237.1 - 7.8 7.5 6.1 14 6.7 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RVP_2 PF08284.11 CDJ67238.1 - 3.2e-08 33.4 0.0 8.1e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ67238.1 - 6.5e-08 33.1 0.0 1.3e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ67238.1 - 9.7e-08 32.5 0.0 2.3e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CDJ67238.1 - 2.3e-05 24.3 1.1 4.1e-05 23.4 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 CDJ67238.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ67238.1 - 0.019 15.3 0.0 0.046 14.0 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 CDJ67238.1 - 0.087 13.1 0.2 0.76 10.1 0.1 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein DUF3130 PF11328.8 CDJ67239.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 DUF1846 PF08903.11 CDJ67240.1 - 0.15 10.6 1.8 0.17 10.4 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) DUF4636 PF15468.6 CDJ67240.1 - 0.65 9.7 7.8 0.77 9.4 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF2052 PF09747.9 CDJ67240.1 - 1.4 9.0 13.7 1.7 8.7 13.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 CDJ67240.1 - 1.7 8.3 7.2 2.2 7.9 7.2 1.3 1 0 0 1 1 1 0 FAM176 family Macoilin PF09726.9 CDJ67240.1 - 2.3 6.7 12.2 2.6 6.5 12.2 1.0 1 0 0 1 1 1 0 Macoilin family Sporozoite_P67 PF05642.11 CDJ67240.1 - 2.9 5.9 13.5 3.3 5.7 13.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ALMT PF11744.8 CDJ67240.1 - 4 6.2 11.2 4.6 5.9 11.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Fmp27 PF10344.9 CDJ67240.1 - 4.1 5.4 8.3 5.3 5.0 8.3 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Paf1 PF03985.13 CDJ67240.1 - 4.2 6.3 14.9 5.2 6.0 14.9 1.1 1 0 0 1 1 1 0 Paf1 Lin-8 PF03353.15 CDJ67240.1 - 4.5 6.7 19.2 5 6.6 19.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FAM60A PF15396.6 CDJ67240.1 - 6.7 6.7 9.1 8.1 6.4 9.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Miga PF10265.9 CDJ67240.1 - 7.2 5.5 11.5 8.2 5.3 11.5 1.1 1 0 0 1 1 1 0 Mitoguardin Menin PF05053.13 CDJ67240.1 - 7.4 4.8 13.0 8.4 4.6 13.0 1.0 1 0 0 1 1 1 0 Menin V_ATPase_I PF01496.19 CDJ67240.1 - 9.9 3.9 10.7 10 3.9 10.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pro_isomerase PF00160.21 CDJ67241.1 - 5.2e-07 30.1 0.0 7.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Adeno_PV PF03910.13 CDJ67241.1 - 1.6 7.3 3.0 2.3 6.9 3.0 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV Mut7-C PF01927.16 CDJ67242.1 - 0.0069 16.5 0.3 0.014 15.5 0.3 1.5 1 0 0 1 1 1 1 Mut7-C RNAse domain FAM60A PF15396.6 CDJ67242.1 - 0.076 13.0 1.6 0.12 12.3 1.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 CDJ67242.1 - 0.082 11.7 4.3 0.11 11.2 4.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CDJ67242.1 - 0.15 11.4 11.8 0.24 10.7 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CemA PF03040.14 CDJ67242.1 - 1.3 8.9 2.7 3.2 7.6 2.7 1.6 1 0 0 1 1 1 0 CemA family DUF4746 PF15928.5 CDJ67242.1 - 3.9 6.8 6.1 5.8 6.2 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Neur_chan_memb PF02932.16 CDJ67242.1 - 4.7 7.2 5.2 7.8 6.5 5.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2052 PF09747.9 CDJ67242.1 - 5.5 7.1 15.4 10 6.2 15.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Suf PF05843.14 CDJ67242.1 - 6.6 6.6 11.2 10 6.0 11.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.7 CDJ67242.1 - 7.1 4.6 9.7 10 4.1 9.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DSHCT PF08148.12 CDJ67244.1 - 1.7e-48 164.4 4.3 4e-47 159.9 4.3 2.2 1 1 0 1 1 1 1 DSHCT (NUC185) domain RskA PF10099.9 CDJ67244.1 - 0.0044 17.3 7.2 0.0044 17.3 7.2 2.2 2 1 0 2 2 2 1 Anti-sigma-K factor rskA PG_binding_2 PF08823.11 CDJ67244.1 - 0.059 13.7 0.0 16 5.9 0.0 3.0 3 0 0 3 3 3 0 Putative peptidoglycan binding domain Ribosomal_60s PF00428.19 CDJ67244.1 - 0.22 12.2 9.0 0.095 13.3 5.7 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4131 PF13567.6 CDJ67244.1 - 0.41 10.3 8.5 1.4 8.5 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CDK2AP PF09806.9 CDJ67244.1 - 4.7 7.2 7.8 0.34 10.9 0.5 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Spt20 PF12090.8 CDJ67244.1 - 9.2 5.8 10.1 14 5.2 10.1 1.2 1 0 0 1 1 1 0 Spt20 family Glyco_transf_5 PF08323.11 CDJ67245.1 - 1.5e-15 57.5 0.1 1.8e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 Starch synthase catalytic domain Ribophorin_I PF04597.14 CDJ67246.1 - 0.21 10.7 0.0 0.29 10.3 0.0 1.1 1 0 0 1 1 1 0 Ribophorin I RT_RNaseH PF17917.1 CDJ67247.1 - 3.4e-21 75.5 0.1 8.7e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ67247.1 - 2.6e-16 59.5 0.4 8.1e-16 57.9 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ67247.1 - 9e-16 58.1 0.1 4.8e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 CDJ67247.1 - 4.7e-11 42.6 0.0 9.7e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 CDJ67247.1 - 3.4e-10 39.7 0.0 6.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 CDJ67247.1 - 6.1e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 CDJ67247.1 - 0.0027 17.9 0.2 0.0068 16.6 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger CCDC71L PF15374.6 CDJ67248.1 - 0.075 12.3 12.8 0.091 12.0 12.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L FAM199X PF15814.5 CDJ67248.1 - 0.21 10.6 6.1 0.25 10.4 6.1 1.1 1 0 0 1 1 1 0 Protein family FAM199X DUF2052 PF09747.9 CDJ67248.1 - 2 8.5 13.4 2.5 8.2 13.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CCSAP PF15748.5 CDJ67248.1 - 2.8 8.1 15.2 3.2 7.8 15.2 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Ndc1_Nup PF09531.10 CDJ67248.1 - 9.7 4.7 15.5 11 4.6 15.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Solute_trans_a PF03619.16 CDJ67249.1 - 2e-26 93.1 0.3 2.6e-26 92.8 0.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Inhibitor_I71 PF12628.7 CDJ67249.1 - 0.071 12.9 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor NUDIX PF00293.28 CDJ67250.1 - 4.8e-19 68.7 0.0 9.2e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CPSF100_C PF13299.6 CDJ67250.1 - 0.00048 20.4 16.6 0.1 12.7 0.6 3.1 3 0 0 3 3 3 3 Cleavage and polyadenylation factor 2 C-terminal DUF2722 PF10846.8 CDJ67250.1 - 0.00052 19.1 1.9 0.00052 19.1 1.9 3.3 2 1 1 3 3 1 1 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ67250.1 - 0.0011 18.6 14.6 0.0011 18.6 14.6 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ67250.1 - 0.0018 18.6 20.8 0.11 12.8 7.6 3.4 2 1 1 3 3 3 2 Anti-sigma-K factor rskA SpoIIP PF07454.11 CDJ67250.1 - 0.0042 16.6 21.8 0.14 11.6 1.6 3.1 3 0 0 3 3 3 3 Stage II sporulation protein P (SpoIIP) AAA_23 PF13476.6 CDJ67250.1 - 0.015 15.8 4.7 0.015 15.8 4.7 3.1 3 0 0 3 3 3 0 AAA domain Ureide_permease PF07168.11 CDJ67250.1 - 0.017 13.9 0.2 0.017 13.9 0.2 3.0 2 1 1 3 3 3 0 Ureide permease TCP PF03634.13 CDJ67250.1 - 0.023 15.3 29.7 0.37 11.3 0.7 3.1 3 0 0 3 3 3 0 TCP family transcription factor DUF572 PF04502.13 CDJ67250.1 - 0.085 12.5 25.8 0.18 11.4 19.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Tim54 PF11711.8 CDJ67250.1 - 0.16 10.7 21.0 0.15 10.8 0.3 3.0 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 CCDC53 PF10152.9 CDJ67250.1 - 0.19 12.2 28.9 0.22 11.9 0.9 3.2 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex SPX PF03105.19 CDJ67250.1 - 0.31 10.9 23.6 0.49 10.3 17.1 2.2 2 0 0 2 2 2 0 SPX domain DUF2076 PF09849.9 CDJ67250.1 - 0.41 10.6 55.2 0.15 12.1 6.6 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) SLC12 PF03522.15 CDJ67250.1 - 0.46 9.5 28.1 0.51 9.3 21.0 2.2 2 0 0 2 2 2 0 Solute carrier family 12 MecA PF05389.12 CDJ67250.1 - 0.54 9.8 20.8 0.056 13.1 0.8 3.1 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) DUF3306 PF11748.8 CDJ67250.1 - 0.56 11.1 26.8 0.23 12.4 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) Band_3_cyto PF07565.13 CDJ67250.1 - 0.77 9.5 30.7 2.2 8.0 5.5 3.1 3 0 0 3 3 3 0 Band 3 cytoplasmic domain GNAT_acetyltr_2 PF13718.6 CDJ67250.1 - 0.91 8.9 23.3 0.62 9.4 0.8 3.1 3 0 0 3 3 3 0 GNAT acetyltransferase 2 Rxt3 PF08642.10 CDJ67250.1 - 3.1 8.6 18.4 6 7.7 1.5 3.3 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 EIIBC-GUT_N PF03612.14 CDJ67250.1 - 3.7 7.3 26.0 1.7 8.3 5.7 3.2 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus KOG2701 PF09762.9 CDJ67250.1 - 4.7 7.4 28.2 1.5 9.0 3.4 3.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein (DUF2037) RIC3 PF15361.6 CDJ67250.1 - 6.1 7.2 20.9 1.8 8.9 1.6 3.3 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 MCU PF04678.13 CDJ67250.1 - 8.3 6.5 25.1 1.6 8.8 1.3 3.1 3 0 0 3 3 3 0 Mitochondrial calcium uniporter tRNA-synt_1b PF00579.25 CDJ67251.1 - 2.6e-23 82.8 0.0 2.6e-23 82.8 0.0 3.3 2 1 1 3 3 3 1 tRNA synthetases class I (W and Y) S4 PF01479.25 CDJ67251.1 - 0.00087 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain DUF1635 PF07795.11 CDJ67253.1 - 0.013 15.3 7.8 0.018 14.9 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) PAP1 PF08601.10 CDJ67253.1 - 0.032 14.0 14.4 0.036 13.8 14.4 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Pap_E4 PF02711.14 CDJ67253.1 - 0.089 13.8 4.9 0.18 12.8 4.9 1.6 1 1 0 1 1 1 0 E4 protein SDP_N PF12278.8 CDJ67253.1 - 0.11 12.6 3.2 0.14 12.3 3.2 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal GREB1 PF15782.5 CDJ67253.1 - 0.22 8.6 7.0 0.21 8.7 7.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF755 PF05501.11 CDJ67253.1 - 3.2 8.0 24.8 4.5 7.6 24.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TFIIA PF03153.13 CDJ67253.1 - 4.3 7.2 10.7 4.7 7.1 10.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ67253.1 - 4.3 5.3 20.2 4.8 5.1 20.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Apt1 PF10351.9 CDJ67253.1 - 6.6 5.5 9.0 6.8 5.4 9.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ67253.1 - 6.6 5.1 10.0 7.3 5.0 10.0 1.1 1 0 0 1 1 1 0 Macoilin family MAP65_ASE1 PF03999.12 CDJ67253.1 - 7.3 5.1 9.7 7.9 5.0 9.7 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4692 PF15763.5 CDJ67253.1 - 8.5 6.8 10.9 9.7 6.6 10.9 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DLIC PF05783.11 CDJ67255.1 - 0.015 14.1 6.3 0.031 13.1 6.3 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) LysE PF01810.18 CDJ67255.1 - 0.064 12.7 0.2 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 LysE type translocator FAST_2 PF08368.12 CDJ67255.1 - 0.08 13.7 0.1 0.25 12.2 0.1 1.8 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 TatC PF00902.18 CDJ67255.1 - 0.43 10.4 1.4 0.72 9.6 1.4 1.3 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) MARVEL PF01284.23 CDJ67255.1 - 1.7 8.7 6.8 0.75 9.8 2.3 2.6 2 1 0 2 2 2 0 Membrane-associating domain SR-25 PF10500.9 CDJ67255.1 - 2.8 7.5 9.0 1.3 8.6 2.2 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GatB_N PF02934.15 CDJ67256.1 - 3.2e-68 230.1 0.1 1.7e-62 211.3 0.0 2.9 2 1 1 3 3 3 2 GatB/GatE catalytic domain TFIIA PF03153.13 CDJ67256.1 - 0.16 12.0 5.7 0.25 11.3 5.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ67256.1 - 0.74 9.4 5.1 1.7 8.2 5.1 1.5 1 0 0 1 1 1 0 Spt20 family PWI PF01480.17 CDJ67257.1 - 0.023 15.0 0.9 0.22 11.9 0.2 2.6 1 1 1 2 2 2 0 PWI domain CNOT1_HEAT PF16418.5 CDJ67257.1 - 0.061 13.4 0.7 0.061 13.4 0.7 2.5 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Pro_racemase PF05544.11 CDJ67257.1 - 0.088 11.8 1.0 0.14 11.2 0.7 1.4 1 1 0 1 1 1 0 Proline racemase Mem_trans PF03547.18 CDJ67257.1 - 0.85 7.9 4.5 0.27 9.6 1.6 1.5 1 1 1 2 2 2 0 Membrane transport protein Dynamin_N PF00350.23 CDJ67258.1 - 3.4e-14 53.2 0.0 2e-13 50.7 0.0 2.1 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 CDJ67258.1 - 6.6e-14 51.5 1.1 1.2e-13 50.6 1.1 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein DUF5600 PF18150.1 CDJ67258.1 - 1.1e-08 35.7 2.1 0.0026 18.3 0.1 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 CDJ67258.1 - 3.2e-08 33.4 0.0 7.7e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.23 CDJ67258.1 - 2.2e-07 30.9 0.0 3.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ67258.1 - 2.8e-05 23.7 0.0 0.00035 20.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 CDJ67258.1 - 0.0006 20.0 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CDJ67258.1 - 0.0066 16.4 0.0 0.52 10.2 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase SUIM_assoc PF16619.5 CDJ67258.1 - 0.018 15.1 0.1 0.041 13.9 0.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 AAA_28 PF13521.6 CDJ67258.1 - 0.021 15.1 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CDJ67258.1 - 0.04 13.6 0.0 3 7.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EF-hand_7 PF13499.6 CDJ67258.1 - 0.067 13.6 0.0 0.28 11.7 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Septin PF00735.18 CDJ67258.1 - 0.23 10.7 0.0 0.79 8.9 0.0 1.8 2 0 0 2 2 2 0 Septin Cpn60_TCP1 PF00118.24 CDJ67259.1 - 1.5e-33 116.2 5.7 1.7e-33 116.0 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NifU_N PF01592.16 CDJ67259.1 - 0.13 12.4 3.3 0.23 11.6 3.3 1.4 1 0 0 1 1 1 0 NifU-like N terminal domain SUIM_assoc PF16619.5 CDJ67260.1 - 0.02 14.9 15.0 0.048 13.7 15.0 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PAP2 PF01569.21 CDJ67260.1 - 0.051 13.3 0.5 0.066 13.0 0.5 1.1 1 0 0 1 1 1 0 PAP2 superfamily Roughex PF06020.11 CDJ67260.1 - 0.19 10.8 9.4 0.23 10.5 9.4 1.0 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ67260.1 - 0.21 11.2 10.2 0.23 11.1 10.2 1.1 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 CDJ67260.1 - 0.27 11.9 11.0 0.33 11.6 11.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4805 PF16063.5 CDJ67260.1 - 1.6 8.0 9.6 1.8 7.8 9.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4805) Ribosomal_60s PF00428.19 CDJ67262.1 - 1.8 9.2 17.2 4 8.1 17.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein eIF-3_zeta PF05091.12 CDJ67263.1 - 0.2 10.6 15.3 0.28 10.1 15.3 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sugar_tr PF00083.24 CDJ67264.1 - 3e-08 33.0 3.9 3.4e-08 32.8 3.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ67264.1 - 2.5e-07 30.0 21.9 3.5e-07 29.5 21.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_60s PF00428.19 CDJ67264.1 - 0.018 15.7 7.8 0.036 14.6 7.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein RRM_1 PF00076.22 CDJ67265.1 - 2.5e-13 49.6 0.0 6.1e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ67265.1 - 0.045 13.9 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif MEDS PF14417.6 CDJ67265.1 - 1.5 8.6 5.8 4.8 7.0 5.0 2.3 1 1 1 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain MRP-L27 PF09809.9 CDJ67266.1 - 6.9e-12 45.2 0.0 7.5e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 PRP4 PF08799.11 CDJ67267.1 - 9.5e-12 44.3 1.0 9.5e-12 44.3 1.0 2.9 4 0 0 4 4 4 1 pre-mRNA processing factor 4 (PRP4) like Spt20 PF12090.8 CDJ67267.1 - 0.0034 17.0 3.1 0.0034 17.0 3.1 3.4 2 1 0 2 2 2 1 Spt20 family DUF1980 PF09323.10 CDJ67267.1 - 2 8.3 4.1 13 5.7 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) SPX PF03105.19 CDJ67268.1 - 8.1e-08 32.6 10.2 8.1e-08 32.6 10.2 3.2 2 1 0 3 3 3 1 SPX domain GMC_oxred_C PF05199.13 CDJ67268.1 - 0.00031 21.3 0.0 0.00031 21.3 0.0 3.4 4 0 0 4 4 4 1 GMC oxidoreductase DUF4834 PF16118.5 CDJ67268.1 - 0.00079 20.3 4.9 0.00079 20.3 4.9 7.5 5 3 1 6 6 6 1 Domain of unknown function (DUF4834) Apt1 PF10351.9 CDJ67268.1 - 0.0013 17.7 77.7 0.005 15.7 15.4 4.1 4 0 0 4 4 4 3 Golgi-body localisation protein domain SUIM_assoc PF16619.5 CDJ67268.1 - 0.0038 17.3 0.0 0.0038 17.3 0.0 10.1 3 3 1 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 SLC12 PF03522.15 CDJ67268.1 - 0.0045 16.1 2.3 0.0045 16.1 2.3 4.0 4 0 0 4 4 4 1 Solute carrier family 12 Spt20 PF12090.8 CDJ67268.1 - 0.0049 16.5 29.9 0.0049 16.5 29.9 6.4 4 2 2 6 6 6 1 Spt20 family BUD22 PF09073.10 CDJ67268.1 - 0.0056 16.1 26.9 0.0056 16.1 26.9 4.3 4 1 0 4 4 4 1 BUD22 GRP PF07172.11 CDJ67268.1 - 0.027 15.1 6.5 0.027 15.1 6.5 4.9 3 1 0 3 3 3 0 Glycine rich protein family NARP1 PF12569.8 CDJ67268.1 - 1.2 7.9 43.8 1.8 7.4 26.3 2.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 GMC_oxred_N PF00732.19 CDJ67269.1 - 4.4e-21 75.5 3.0 1.3e-13 51.0 0.0 3.4 1 1 1 3 3 3 3 GMC oxidoreductase DUF3371 PF11851.8 CDJ67269.1 - 1 10.5 24.7 0.5 11.5 4.4 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3371) Suf PF05843.14 CDJ67269.1 - 2.3 8.1 31.7 0.12 12.4 6.2 3.1 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ67269.1 - 2.5 8.1 22.0 0.054 13.6 2.9 3.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF755 PF05501.11 CDJ67270.1 - 1.1 9.6 7.7 1.7 9.0 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF1712 PF08217.11 CDJ67271.1 - 0.031 12.8 0.1 0.043 12.3 0.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Zein-binding PF04576.15 CDJ67271.1 - 0.042 14.1 1.8 0.14 12.4 0.1 2.5 2 0 0 2 2 2 0 Zein-binding Phage_GP20 PF06810.11 CDJ67271.1 - 0.083 12.7 0.6 0.35 10.7 0.1 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 SecA_SW PF07516.13 CDJ67271.1 - 0.5 10.4 6.6 0.093 12.8 0.5 2.3 2 1 0 2 2 2 0 SecA Wing and Scaffold domain RdRP_1 PF00680.20 CDJ67272.1 - 2e-21 76.1 0.0 2.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP_4 PF02123.16 CDJ67272.1 - 7.9e-08 31.6 0.0 9.6e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Viral RNA-directed RNA-polymerase Actin PF00022.19 CDJ67273.1 - 0.0041 15.8 0.0 0.23 10.0 0.0 2.1 2 0 0 2 2 2 2 Actin SR-25 PF10500.9 CDJ67273.1 - 0.58 9.7 13.3 0.75 9.4 13.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF508 PF04370.12 CDJ67273.1 - 0.69 9.6 4.1 0.99 9.1 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Myf5 PF12232.8 CDJ67275.1 - 1.2 9.9 0.1 1.2 9.9 0.1 2.4 2 1 0 2 2 2 0 Myogenic determination factor 5 BAF1_ABF1 PF04684.13 CDJ67275.1 - 1.3 8.0 23.0 1.6 7.7 23.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FAM199X PF15814.5 CDJ67275.1 - 4 6.4 19.6 5.1 6.0 19.6 1.1 1 0 0 1 1 1 0 Protein family FAM199X Peptidase_S10 PF00450.22 CDJ67276.1 - 0.24 10.8 21.0 0.3 10.5 21.0 1.0 1 0 0 1 1 1 0 Serine carboxypeptidase Hamartin PF04388.12 CDJ67276.1 - 8.8 4.9 39.1 11 4.6 39.1 1.1 1 0 0 1 1 1 0 Hamartin protein Cmyb_C PF09316.10 CDJ67277.1 - 0.024 14.3 0.8 0.024 14.3 0.8 1.5 2 0 0 2 2 2 0 C-myb, C-terminal SPX PF03105.19 CDJ67277.1 - 0.36 10.7 10.8 0.43 10.4 10.8 1.1 1 0 0 1 1 1 0 SPX domain Proteasome PF00227.26 CDJ67279.1 - 3.6e-32 111.4 0.3 8.2e-32 110.2 0.0 1.7 1 1 1 2 2 2 1 Proteasome subunit AAA_18 PF13238.6 CDJ67280.1 - 1e-22 81.1 0.0 1.3e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CDJ67280.1 - 8.9e-08 32.6 0.1 4e-07 30.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ67280.1 - 2.5e-05 24.5 0.0 0.00011 22.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ67280.1 - 9.4e-05 22.9 0.2 0.00022 21.6 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain ADK PF00406.22 CDJ67280.1 - 0.00033 20.8 0.0 0.006 16.7 0.0 2.2 2 1 0 2 2 2 1 Adenylate kinase AAA PF00004.29 CDJ67280.1 - 0.0011 19.4 0.0 0.0029 18.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CDJ67280.1 - 0.0014 18.9 0.1 0.0043 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDJ67280.1 - 0.003 17.8 0.0 0.0056 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 CDJ67280.1 - 0.0043 16.5 0.1 0.0092 15.5 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Cytidylate_kin PF02224.18 CDJ67280.1 - 0.0063 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase NACHT PF05729.12 CDJ67280.1 - 0.008 16.1 0.1 0.044 13.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 CDJ67280.1 - 0.0093 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.22 CDJ67280.1 - 0.0094 16.3 0.0 0.019 15.3 0.0 1.5 2 0 0 2 2 1 1 RNA helicase SKI PF01202.22 CDJ67280.1 - 0.0096 16.1 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase IstB_IS21 PF01695.17 CDJ67280.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein IPPT PF01715.17 CDJ67280.1 - 0.017 14.9 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 IPP transferase RuvB_N PF05496.12 CDJ67280.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CDJ67280.1 - 0.026 13.7 0.0 0.055 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 CDJ67280.1 - 0.028 14.5 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 CDJ67280.1 - 0.045 13.6 0.4 0.45 10.3 0.1 2.2 2 1 0 2 2 2 0 Deoxynucleoside kinase ParA PF10609.9 CDJ67280.1 - 0.047 13.1 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_24 PF13479.6 CDJ67280.1 - 0.056 13.2 0.0 0.13 11.9 0.0 1.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CDJ67280.1 - 0.065 13.3 0.0 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase MeaB PF03308.16 CDJ67280.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 CDJ67280.1 - 0.073 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 CDJ67280.1 - 0.084 12.8 0.0 0.19 11.6 0.0 1.6 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 CDJ67280.1 - 0.084 12.8 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF2075 PF09848.9 CDJ67280.1 - 0.086 12.1 0.0 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 CDJ67280.1 - 0.091 12.5 0.2 0.86 9.3 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 CDJ67280.1 - 0.093 12.5 0.1 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 CDJ67280.1 - 0.096 11.9 0.0 0.19 11.0 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 CDJ67280.1 - 0.12 11.6 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 CDJ67280.1 - 0.15 11.6 0.0 0.95 9.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 CDJ67282.1 - 0.36 9.8 5.3 0.45 9.5 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Ribosomal_60s PF00428.19 CDJ67282.1 - 6 7.5 15.9 9.2 6.9 15.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sof1 PF04158.14 CDJ67283.1 - 4.2e-10 39.7 22.3 1.1e-09 38.4 21.0 2.0 1 1 1 2 2 2 1 Sof1-like domain WD40 PF00400.32 CDJ67283.1 - 5.9e-07 30.1 0.1 0.021 15.7 0.0 4.0 3 1 1 4 4 4 2 WD domain, G-beta repeat BBS2_C PF14782.6 CDJ67283.1 - 0.00018 20.4 7.4 0.00025 20.0 7.4 1.2 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal Spt20 PF12090.8 CDJ67283.1 - 0.18 11.4 32.0 0.21 11.2 28.6 2.1 2 0 0 2 2 2 0 Spt20 family eIF-3_zeta PF05091.12 CDJ67283.1 - 0.18 10.7 12.1 0.25 10.3 12.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EPL1 PF10513.9 CDJ67283.1 - 1.6 9.1 11.2 3 8.2 11.2 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like Pex14_N PF04695.13 CDJ67283.1 - 3.7 8.2 15.9 1.9 9.1 12.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dymeclin PF09742.9 CDJ67284.1 - 1.7e-83 281.1 3.9 4.5e-76 256.6 0.0 3.1 1 1 2 3 3 3 2 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 CDJ67284.1 - 7.1e-83 279.1 78.0 2.3e-55 188.2 3.3 6.1 2 1 4 6 6 6 5 High-temperature-induced dauer-formation protein SR-25 PF10500.9 CDJ67284.1 - 3.6e-06 26.7 16.5 3.6e-06 26.7 16.5 3.9 3 1 0 3 3 3 2 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ67284.1 - 0.00021 20.4 10.2 0.00021 20.4 10.2 4.4 3 1 1 4 4 4 2 Protein of unknown function (DUF2722) Cwf_Cwc_15 PF04889.12 CDJ67284.1 - 0.0012 18.7 0.4 0.0012 18.7 0.4 3.4 3 1 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein CCDC106 PF15794.5 CDJ67284.1 - 0.005 16.6 6.8 0.005 16.6 6.8 3.3 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 106 Mitofilin PF09731.9 CDJ67284.1 - 0.28 10.0 57.5 0.21 10.4 23.1 3.0 3 0 0 3 3 3 0 Mitochondrial inner membrane protein CDC45 PF02724.14 CDJ67284.1 - 0.62 8.3 44.0 0.1 10.9 1.8 3.1 3 0 0 3 3 3 0 CDC45-like protein CDK5_activator PF03261.15 CDJ67284.1 - 5.7 6.4 32.1 0.33 10.5 16.5 2.7 3 0 0 3 3 3 0 Cyclin-dependent kinase 5 activator protein MRP-S26 PF14943.6 CDJ67286.1 - 0.089 12.7 18.0 0.12 12.3 18.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 MAJIN PF15077.6 CDJ67286.1 - 0.17 11.7 13.8 0.22 11.3 13.8 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein TCP PF03634.13 CDJ67286.1 - 0.65 10.6 24.2 0.92 10.1 24.2 1.3 1 0 0 1 1 1 0 TCP family transcription factor CDC27 PF09507.10 CDJ67286.1 - 0.85 8.9 27.9 1.1 8.6 27.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2126 PF09899.9 CDJ67286.1 - 0.96 7.4 10.8 1.1 7.3 10.8 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF5523 PF17661.1 CDJ67286.1 - 1.2 8.8 22.6 1.5 8.5 22.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF4551 PF15087.6 CDJ67286.1 - 2.4 6.9 19.7 2.7 6.7 19.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) V_ATPase_I PF01496.19 CDJ67286.1 - 3.6 5.4 16.8 4.2 5.2 16.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 CDJ67286.1 - 4.3 7.8 21.6 5.9 7.3 21.6 1.1 1 0 0 1 1 1 0 AAA domain PA26 PF04636.13 CDJ67286.1 - 6 5.7 14.0 6.9 5.5 14.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SLC12 PF03522.15 CDJ67286.1 - 9 5.2 19.8 10 5.0 19.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Ank_5 PF13857.6 CDJ67287.1 - 0.0041 17.4 0.0 5.7 7.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Pkinase PF00069.25 CDJ67288.1 - 2.6e-32 112.2 0.0 1.3e-31 109.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ67288.1 - 9.8e-17 61.1 0.0 7.4e-15 54.9 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Collagen PF01391.18 CDJ67288.1 - 3.7e-05 23.4 17.0 0.00011 21.9 17.0 1.8 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Kinase-like PF14531.6 CDJ67288.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RskA PF10099.9 CDJ67289.1 - 0.00087 19.6 60.5 0.0028 18.0 0.0 6.1 1 1 3 4 4 4 2 Anti-sigma-K factor rskA Roc PF08477.13 CDJ67289.1 - 1.6 9.0 3.7 4.3 7.6 3.7 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ribosomal_S21e PF01249.18 CDJ67290.1 - 7.4e-18 64.4 0.0 9.5e-18 64.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e DUF4148 PF13663.6 CDJ67291.1 - 0.048 13.8 15.8 0.35 11.1 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) NAP PF00956.18 CDJ67291.1 - 0.13 11.4 1.3 0.17 11.0 1.3 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) OEP PF02321.18 CDJ67291.1 - 0.53 10.1 10.7 0.025 14.4 3.6 1.9 2 0 0 2 2 2 0 Outer membrane efflux protein DUF2076 PF09849.9 CDJ67292.1 - 0.0016 18.5 25.3 0.0021 18.2 22.4 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) CCDC53 PF10152.9 CDJ67292.1 - 0.0028 18.1 12.5 0.04 14.3 12.4 2.3 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex DUF2201_N PF13203.6 CDJ67292.1 - 0.0038 16.9 4.2 0.0071 16.0 4.2 1.4 1 0 0 1 1 1 1 Putative metallopeptidase domain DUF572 PF04502.13 CDJ67292.1 - 0.0062 16.2 5.9 0.011 15.3 5.9 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF572) SUIM_assoc PF16619.5 CDJ67292.1 - 0.011 15.8 5.3 0.011 15.8 5.3 3.4 2 1 0 2 2 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4407 PF14362.6 CDJ67292.1 - 0.018 14.4 8.4 0.036 13.4 8.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TCP PF03634.13 CDJ67292.1 - 0.041 14.5 11.3 0.093 13.3 11.3 1.5 1 0 0 1 1 1 0 TCP family transcription factor DUF4175 PF13779.6 CDJ67292.1 - 0.075 10.9 32.1 0.11 10.4 32.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.14 CDJ67292.1 - 0.15 12.0 16.5 0.32 11.0 16.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Glyco_hydro_63 PF03200.16 CDJ67292.1 - 0.4 9.4 7.5 0.033 13.0 2.8 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 63 C-terminal domain Het-C PF07217.11 CDJ67292.1 - 0.51 8.8 10.5 0.89 8.0 10.5 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Neur_chan_memb PF02932.16 CDJ67292.1 - 0.88 9.6 9.3 1.8 8.5 9.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 CDJ67292.1 - 1.2 8.0 34.5 0.026 13.5 13.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4471 PF14740.6 CDJ67292.1 - 2.2 7.4 12.1 2.5 7.3 10.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) MAJIN PF15077.6 CDJ67292.1 - 3.2 7.5 10.8 5.7 6.7 10.8 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein FAM60A PF15396.6 CDJ67292.1 - 3.9 7.4 10.2 9.1 6.2 10.2 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 CDJ67292.1 - 3.9 5.5 12.9 5.6 5.0 12.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2844 PF11005.8 CDJ67292.1 - 4.1 7.4 11.4 0.15 12.1 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2844) AAA_23 PF13476.6 CDJ67292.1 - 4.4 7.8 17.4 0.45 11.0 12.7 1.9 2 0 0 2 2 1 0 AAA domain RR_TM4-6 PF06459.12 CDJ67292.1 - 5.3 6.8 14.5 8.8 6.1 14.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ67292.1 - 7.3 5.2 18.7 12 4.6 18.7 1.2 1 0 0 1 1 1 0 Presenilin GET2 PF08690.10 CDJ67292.1 - 9.2 5.8 20.0 21 4.7 20.0 1.6 1 0 0 1 1 1 0 GET complex subunit GET2 MDM31_MDM32 PF08118.11 CDJ67292.1 - 9.3 4.8 10.7 42 2.6 0.0 2.4 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins Hamartin PF04388.12 CDJ67294.1 - 2.3 6.8 19.1 3.1 6.4 19.1 1.2 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 CDJ67294.1 - 5.7 6.8 45.9 13 5.6 45.9 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CDJ67295.1 - 2e-54 184.7 1.5 2.2e-52 178.0 0.4 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ67295.1 - 9.2e-19 67.7 0.0 1.4e-16 60.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CDJ67295.1 - 4.2e-05 23.6 8.4 0.00056 19.9 8.4 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ67295.1 - 0.00085 18.7 0.1 0.0017 17.7 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ67295.1 - 0.0039 16.8 1.1 0.011 15.3 0.6 1.9 2 1 0 2 2 2 1 RIO1 family TCP PF03634.13 CDJ67295.1 - 0.02 15.5 2.6 0.03 14.9 2.6 1.2 1 0 0 1 1 1 0 TCP family transcription factor Ndc1_Nup PF09531.10 CDJ67295.1 - 0.028 13.1 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Choline_kinase PF01633.20 CDJ67295.1 - 0.045 13.3 0.2 0.096 12.3 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Spt20 PF12090.8 CDJ67295.1 - 0.075 12.6 7.1 0.13 11.9 7.1 1.4 1 0 0 1 1 1 0 Spt20 family SprA-related PF12118.8 CDJ67295.1 - 0.096 11.8 14.4 0.13 11.3 14.4 1.1 1 0 0 1 1 1 0 SprA-related family DUF913 PF06025.12 CDJ67295.1 - 0.23 10.4 2.2 0.36 9.8 2.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CDJ67295.1 - 0.37 9.5 3.2 0.51 9.0 3.2 1.1 1 0 0 1 1 1 0 Presenilin FTA2 PF13095.6 CDJ67295.1 - 0.45 10.1 4.5 4.9 6.7 4.5 2.2 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CDJ67295.1 - 0.54 9.0 9.7 4.9 5.8 9.7 2.0 1 1 0 1 1 1 0 Fungal protein kinase Corona_nucleoca PF00937.18 CDJ67295.1 - 0.6 9.1 7.5 0.83 8.6 7.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CDK2AP PF09806.9 CDJ67295.1 - 0.84 9.7 12.3 1.8 8.6 12.3 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CCSAP PF15748.5 CDJ67295.1 - 1.6 8.8 10.0 2.4 8.3 10.0 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Herpes_pp85 PF04637.12 CDJ67295.1 - 2.8 6.3 7.2 4.3 5.6 7.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) MTBP_C PF14920.6 CDJ67295.1 - 3.9 7.2 11.3 5.8 6.6 11.3 1.1 1 0 0 1 1 1 0 MDM2-binding CCDC53 PF10152.9 CDJ67295.1 - 4.7 7.6 6.7 7.5 6.9 6.7 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PhnG PF06754.12 CDJ67295.1 - 5.4 6.9 8.3 9.9 6.1 8.3 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG CNDH2_M PF16869.5 CDJ67295.1 - 8 7.2 11.3 14 6.4 11.3 1.3 1 0 0 1 1 1 0 PF16858 HTH_Tnp_IS1 PF12759.7 CDJ67296.1 - 0.035 13.7 0.5 0.083 12.5 0.2 1.7 2 0 0 2 2 2 0 InsA C-terminal domain BRCT PF00533.26 CDJ67297.1 - 2.3e-05 24.7 0.0 8.5e-05 22.9 0.0 1.9 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Ribosomal_60s PF00428.19 CDJ67299.1 - 0.26 11.9 10.3 0.29 11.7 10.3 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Chorion_2 PF03964.15 CDJ67299.1 - 8.7 7.3 9.9 9.8 7.1 9.9 1.1 1 0 0 1 1 1 0 Chorion family 2 zf-RING_UBOX PF13445.6 CDJ67300.1 - 3.7e-07 30.1 3.8 3.7e-07 30.1 3.8 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ67300.1 - 8.7e-05 22.4 7.8 8.7e-05 22.4 7.8 2.6 3 0 0 3 3 2 1 zinc-RING finger domain SR-25 PF10500.9 CDJ67300.1 - 0.00023 20.8 12.5 0.00023 20.8 12.5 3.0 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ67300.1 - 0.0016 18.4 0.7 0.0016 18.4 0.7 3.1 3 1 0 3 3 2 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ67300.1 - 0.0023 18.3 0.2 0.0023 18.3 0.2 4.1 1 1 2 3 3 2 1 Anti-sigma-K factor rskA zf-C3HC4 PF00097.25 CDJ67300.1 - 0.0038 17.1 8.3 0.0038 17.1 8.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ67300.1 - 0.023 15.0 11.7 0.023 15.0 11.7 2.5 2 0 0 2 2 2 0 Ring finger domain Peroxin-3 PF04882.12 CDJ67300.1 - 0.069 12.1 7.9 0.17 10.9 7.8 1.5 1 1 0 1 1 1 0 Peroxin-3 Spt20 PF12090.8 CDJ67300.1 - 1.7 8.2 15.1 0.14 11.7 5.8 2.1 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 CDJ67300.1 - 2.8 8.9 5.9 3.3 8.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ67300.1 - 3.1 6.5 5.5 6.8 5.3 0.1 2.1 2 0 0 2 2 2 0 Presenilin RskA PF10099.9 CDJ67301.1 - 9.2e-05 22.8 9.4 9.2e-05 22.8 9.4 7.8 4 3 4 8 8 8 2 Anti-sigma-K factor rskA MFS_1_like PF12832.7 CDJ67301.1 - 0.0019 17.2 0.0 0.025 13.4 0.0 2.7 2 1 0 2 2 2 1 MFS_1 like family SPX PF03105.19 CDJ67301.1 - 0.0058 16.6 0.1 0.0058 16.6 0.1 2.2 2 1 0 2 2 2 1 SPX domain Neur_chan_memb PF02932.16 CDJ67301.1 - 0.11 12.6 1.3 0.45 10.5 0.6 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region N6_N4_Mtase PF01555.18 CDJ67303.1 - 0.00036 20.3 0.0 28 4.3 0.0 3.4 3 1 0 3 3 3 2 DNA methylase SUIM_assoc PF16619.5 CDJ67304.1 - 0.00012 22.0 0.0 0.00012 22.0 0.0 8.0 4 2 2 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 PAP1 PF08601.10 CDJ67304.1 - 0.014 15.2 1.8 0.014 15.2 1.8 4.1 2 2 1 4 4 4 0 Transcription factor PAP1 TFIIA PF03153.13 CDJ67305.1 - 0.44 10.5 13.5 0.6 10.0 13.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ67305.1 - 1.4 8.5 15.8 2.2 7.9 15.8 1.2 1 0 0 1 1 1 0 Spt20 family DASH_Dad2 PF08654.10 CDJ67306.1 - 0.024 15.0 0.3 0.66 10.4 0.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 DUF2459 PF09601.10 CDJ67306.1 - 0.14 12.0 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) RRM_1 PF00076.22 CDJ67307.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.6 CDJ67307.1 - 2.8 7.2 31.0 0.085 12.2 9.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Cadherin_2 PF08266.12 CDJ67308.1 - 6.9 6.6 9.0 7.8 6.4 2.8 2.7 1 1 1 2 2 2 0 Cadherin-like DUF572 PF04502.13 CDJ67308.1 - 9.4 5.8 19.1 12 5.4 19.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) BPL_N PF09825.9 CDJ67308.1 - 9.4 5.2 19.1 12 4.9 19.1 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Nucleoporin2 PF04096.14 CDJ67309.1 - 1.2e-40 139.1 0.0 1.2e-40 139.1 0.0 3.5 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 CDJ67309.1 - 2.7e-23 82.6 281.7 1.5e-08 35.4 38.3 22.4 8 5 10 19 19 19 8 Nucleoporin FG repeat region Sushi PF00084.20 CDJ67310.1 - 1.8e-08 34.9 0.0 3.3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) IMUP PF15761.5 CDJ67310.1 - 0.0087 16.7 6.8 0.0087 16.7 6.8 6.1 5 1 0 5 5 5 3 Immortalisation up-regulated protein EPL1 PF10513.9 CDJ67310.1 - 0.71 10.2 0.0 0.71 10.2 0.0 3.9 5 0 0 5 5 5 0 Enhancer of polycomb-like SR-25 PF10500.9 CDJ67310.1 - 0.98 9.0 62.9 0.14 11.8 10.1 5.0 5 0 0 5 5 5 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ67311.1 - 1.2e-07 31.6 16.8 1.3e-07 31.5 16.8 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 CDJ67311.1 - 0.0011 18.7 11.3 0.0013 18.6 11.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Lin-8 PF03353.15 CDJ67311.1 - 0.042 13.4 6.0 0.05 13.2 6.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF5102 PF17104.5 CDJ67311.1 - 0.044 13.8 8.5 0.052 13.6 8.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Dehydrin PF00257.19 CDJ67311.1 - 0.15 12.6 9.4 0.2 12.2 9.4 1.3 1 0 0 1 1 1 0 Dehydrin FancD2 PF14631.6 CDJ67311.1 - 0.16 9.3 7.0 0.17 9.3 7.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Pox_A12 PF04651.13 CDJ67311.1 - 0.17 11.9 5.7 0.23 11.5 5.7 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein DUF4614 PF15391.6 CDJ67311.1 - 0.33 10.9 10.7 0.37 10.8 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF4603 PF15376.6 CDJ67311.1 - 0.47 7.8 9.7 0.48 7.8 9.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Nucleo_P87 PF07267.11 CDJ67311.1 - 0.57 9.0 9.6 0.58 8.9 9.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4228 PF14009.6 CDJ67311.1 - 0.58 10.5 10.0 0.6 10.5 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF3827 PF12877.7 CDJ67311.1 - 0.65 8.3 10.9 0.7 8.2 10.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MRC1 PF09444.10 CDJ67311.1 - 0.93 10.0 13.1 0.5 10.9 10.7 1.7 1 1 1 2 2 2 0 MRC1-like domain IPP-2 PF04979.14 CDJ67311.1 - 1.9 9.2 10.4 2.8 8.7 10.4 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) CSG2 PF16965.5 CDJ67311.1 - 2.1 7.2 2.9 2.6 6.9 2.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DTHCT PF08070.11 CDJ67311.1 - 3 8.6 17.7 49 4.7 17.7 2.2 1 1 0 1 1 1 0 DTHCT (NUC029) region CDC45 PF02724.14 CDJ67311.1 - 3.5 5.8 12.5 3.9 5.6 12.5 1.0 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 CDJ67311.1 - 4.6 6.9 16.7 6.2 6.5 16.7 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 polyprenyl_synt PF00348.17 CDJ67312.1 - 2.5e-52 177.5 0.0 5.1e-52 176.5 0.0 1.5 2 0 0 2 2 2 1 Polyprenyl synthetase Pkinase PF00069.25 CDJ67313.1 - 5.1e-12 45.7 0.1 6.6e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ67313.1 - 0.0015 17.8 0.0 0.035 13.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase W2 PF02020.18 CDJ67314.1 - 0.39 10.9 3.8 0.64 10.2 3.5 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon RVT_1 PF00078.27 CDJ67315.1 - 0.00021 20.9 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3552 PF12072.8 CDJ67315.1 - 0.12 11.8 1.2 0.16 11.3 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Rft-1 PF04506.13 CDJ67317.1 - 8.3e-14 51.2 2.1 7e-08 31.7 0.9 2.1 2 0 0 2 2 2 2 Rft protein Sad1_UNC PF07738.13 CDJ67318.1 - 3.4e-13 49.8 0.0 1.1e-12 48.1 0.0 1.9 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SNF2_N PF00176.23 CDJ67320.1 - 9.8e-69 231.7 0.5 4.8e-68 229.4 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ67320.1 - 2.2e-18 66.6 0.1 1.2e-17 64.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CDJ67320.1 - 2e-12 46.9 0.7 2e-12 46.9 0.7 1.9 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 CDJ67320.1 - 3.7e-07 30.3 0.2 1.5e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ67320.1 - 7.2e-06 25.9 0.9 3.4e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4440 PF14534.6 CDJ67321.1 - 0.75 10.2 6.3 90 3.5 0.1 4.9 2 1 5 7 7 7 0 Domain of unknown function (DUF4440) Spt20 PF12090.8 CDJ67322.1 - 0.00086 19.0 15.4 0.0016 18.1 15.4 1.4 1 0 0 1 1 1 1 Spt20 family rve PF00665.26 CDJ67323.1 - 1.1e-05 25.6 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Surface_antigen PF11054.8 CDJ67324.1 - 5e-73 245.8 6.5 7.8e-73 245.1 6.5 1.2 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen zinc_ribbon_10 PF10058.9 CDJ67324.1 - 0.067 12.9 0.0 9.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Transglut_C PF00927.22 CDJ67324.1 - 0.18 12.0 0.1 0.31 11.2 0.1 1.3 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain DUF4495 PF14906.6 CDJ67327.1 - 0.072 12.1 0.1 0.089 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) RNase_H2_suC PF08615.11 CDJ67330.1 - 1.1e-12 48.3 0.0 2.9e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RIFIN PF02009.16 CDJ67330.1 - 0.16 11.8 0.5 0.38 10.6 0.5 1.8 1 1 0 1 1 1 0 Rifin PsbQ PF05757.11 CDJ67330.1 - 0.81 9.4 6.6 0.071 12.8 0.7 2.0 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) UPF0016 PF01169.19 CDJ67331.1 - 1.2e-33 115.3 19.4 3.6e-19 68.9 3.9 3.3 2 1 1 3 3 3 2 Uncharacterized protein family UPF0016 B12-binding PF02310.19 CDJ67331.1 - 0.057 13.5 0.1 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 B12 binding domain DUF4131 PF13567.6 CDJ67331.1 - 7.3 6.2 8.7 5.2 6.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) YL1 PF05764.13 CDJ67333.1 - 0.0025 18.0 14.0 0.0034 17.5 14.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 CDJ67333.1 - 0.0076 15.7 15.3 0.011 15.2 15.3 1.2 1 0 0 1 1 1 1 SDA1 LAP1C PF05609.12 CDJ67333.1 - 0.22 10.6 9.2 0.29 10.2 9.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SGT1 PF07093.11 CDJ67333.1 - 8.8 4.6 8.5 0.71 8.2 3.9 1.4 2 0 0 2 2 2 0 SGT1 protein Cyclin_C PF02984.19 CDJ67334.1 - 0.00029 20.9 0.2 0.00029 20.9 0.2 3.2 3 1 0 3 3 3 1 Cyclin, C-terminal domain SR-25 PF10500.9 CDJ67334.1 - 1.5 8.4 39.8 1.8 8.1 7.4 3.6 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein HEAT PF02985.22 CDJ67335.1 - 7.5e-06 25.8 46.6 0.0053 16.9 0.0 11.8 13 0 0 13 13 10 2 HEAT repeat HEAT_2 PF13646.6 CDJ67335.1 - 0.00022 21.5 11.1 0.0051 17.2 5.8 11.9 9 5 4 13 13 9 4 HEAT repeats Cnd1 PF12717.7 CDJ67335.1 - 0.0003 20.8 0.4 2.4 8.2 0.0 4.9 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 SPX PF03105.19 CDJ67335.1 - 0.13 12.2 32.4 0.016 15.2 2.8 3.5 2 1 1 3 3 3 0 SPX domain SID-1_RNA_chan PF13965.6 CDJ67335.1 - 0.27 9.6 0.1 0.4 9.0 0.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spt20 PF12090.8 CDJ67335.1 - 0.55 9.8 50.1 0.81 9.3 25.0 3.3 3 0 0 3 3 3 0 Spt20 family DUF2722 PF10846.8 CDJ67335.1 - 0.68 8.8 37.4 0.61 9.0 19.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) DUF4042 PF13251.6 CDJ67335.1 - 0.68 9.6 10.6 2.7 7.7 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) DUF913 PF06025.12 CDJ67335.1 - 0.72 8.8 4.4 0.91 8.4 0.4 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) SpoIIP PF07454.11 CDJ67335.1 - 0.9 8.9 6.7 0.12 11.9 1.7 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4746 PF15928.5 CDJ67335.1 - 1.2 8.5 3.9 3.1 7.1 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RBP_receptor PF14752.6 CDJ67335.1 - 1.6 7.2 2.9 2.6 6.5 2.9 1.2 1 0 0 1 1 1 0 Retinol binding protein receptor Band_3_cyto PF07565.13 CDJ67335.1 - 4.6 7.0 7.2 11 5.7 4.7 2.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2956 PF11169.8 CDJ67335.1 - 8.8 6.6 22.8 0.58 10.4 9.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) V_ATPase_I PF01496.19 CDJ67335.1 - 9.5 4.0 6.2 19 3.0 6.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nrap_D5 PF17406.2 CDJ67336.1 - 0.97 9.2 0.0 0.97 9.2 0.0 3.3 6 0 0 6 6 6 0 Nrap protein PAP/OAS1-like domain 5 Exo_endo_phos PF03372.23 CDJ67337.1 - 3.4e-05 23.5 0.0 4.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3446 PF11928.8 CDJ67337.1 - 0.0055 17.0 6.6 0.018 15.3 6.3 1.9 2 0 0 2 2 2 1 Early growth response N-terminal domain Lin-8 PF03353.15 CDJ67337.1 - 0.0071 15.9 1.7 0.0086 15.7 1.7 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ67337.1 - 0.0097 15.5 13.2 0.0097 15.5 13.2 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 CDJ67337.1 - 0.014 16.0 4.4 0.014 16.0 4.4 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain Activator_LAG-3 PF11498.8 CDJ67337.1 - 0.25 10.3 21.2 0.76 8.7 20.0 1.9 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF4834 PF16118.5 CDJ67337.1 - 0.7 10.9 6.5 8.8 7.4 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) IMUP PF15761.5 CDJ67337.1 - 0.9 10.3 10.9 2.5 8.9 10.9 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein EBP50_C PF09007.11 CDJ67337.1 - 1.4 9.9 9.4 1.2 10.2 4.0 2.2 2 0 0 2 2 2 0 EBP50, C-terminal CDK2AP PF09806.9 CDJ67337.1 - 7.1 6.6 11.5 2.4 8.2 1.7 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein GREB1 PF15782.5 CDJ67338.1 - 0.18 8.9 31.4 0.2 8.8 31.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LTV PF04180.14 CDJ67338.1 - 0.23 11.2 25.0 0.3 10.8 25.0 1.1 1 0 0 1 1 1 0 Low temperature viability protein SRP-alpha_N PF04086.13 CDJ67338.1 - 0.57 10.0 31.2 0.69 9.8 31.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Asp-B-Hydro_N PF05279.11 CDJ67338.1 - 0.65 10.0 19.4 0.72 9.9 19.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAT1 PF09770.9 CDJ67338.1 - 1.6 6.9 40.6 1.6 6.9 40.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.11 CDJ67338.1 - 1.8 7.0 27.7 2 6.8 27.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 SPX PF03105.19 CDJ67338.1 - 2.1 8.2 30.0 2.4 8.0 30.0 1.1 1 0 0 1 1 1 0 SPX domain DUF572 PF04502.13 CDJ67338.1 - 2.1 7.9 25.6 2.4 7.7 25.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAP1 PF08601.10 CDJ67338.1 - 9.6 5.8 30.8 16 5.1 30.8 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 CwfJ_C_2 PF04676.14 CDJ67339.1 - 2.1e-10 41.4 0.0 3.8e-08 34.1 0.0 2.1 1 1 1 2 2 2 2 Protein similar to CwfJ C-terminus 2 IMUP PF15761.5 CDJ67341.1 - 0.86 10.3 28.1 1 10.1 8.7 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein Secretin_N_2 PF07655.13 CDJ67341.1 - 1.1 9.8 14.4 4.9 7.8 3.2 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain RskA PF10099.9 CDJ67342.1 - 0.00083 19.7 11.5 0.00083 19.7 11.5 3.6 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Neur_chan_memb PF02932.16 CDJ67342.1 - 1.8 8.6 24.5 1.2 9.2 5.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_60s PF00428.19 CDJ67344.1 - 0.028 15.0 3.8 0.028 15.0 3.8 3.7 2 1 1 3 3 3 0 60s Acidic ribosomal protein SOBP PF15279.6 CDJ67344.1 - 1 9.9 27.1 2.6 8.6 11.9 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein Exonuc_VII_L PF02601.15 CDJ67344.1 - 2.1 7.8 37.6 0.71 9.4 18.0 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit ATP-synt_ab PF00006.25 CDJ67345.1 - 3.8e-60 203.2 0.0 8.9e-60 202.0 0.0 1.6 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDJ67345.1 - 1.4e-18 67.2 2.7 5.3e-18 65.3 2.7 2.0 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_16 PF13191.6 CDJ67345.1 - 1.4e-05 25.6 0.0 1.4e-05 25.6 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain RnfC_N PF13375.6 CDJ67345.1 - 0.00069 19.5 1.1 0.0053 16.7 0.6 2.4 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain DUF2722 PF10846.8 CDJ67345.1 - 0.0015 17.5 7.3 0.037 13.0 1.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) NB-ARC PF00931.22 CDJ67345.1 - 0.0072 15.5 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 CDJ67345.1 - 0.029 14.8 0.4 0.47 10.9 0.2 2.7 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CDJ67345.1 - 0.068 12.5 1.4 0.14 11.5 0.3 2.0 2 0 0 2 2 2 0 KaiC RsgA_GTPase PF03193.16 CDJ67345.1 - 0.077 12.9 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 CDJ67345.1 - 0.11 13.0 1.7 0.13 12.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter CENP-L PF13092.6 CDJ67345.1 - 0.16 12.2 0.7 0.22 11.7 0.0 1.5 2 0 0 2 2 1 0 Kinetochore complex Sim4 subunit Fta1 NACHT PF05729.12 CDJ67345.1 - 0.16 11.8 2.1 0.18 11.7 0.2 2.1 2 1 0 2 2 2 0 NACHT domain OMP_b-brl PF13505.6 CDJ67345.1 - 0.2 11.8 1.6 4.1 7.5 0.3 2.3 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain AAA_22 PF13401.6 CDJ67345.1 - 0.22 11.8 2.4 4.3 7.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain DUF4834 PF16118.5 CDJ67345.1 - 0.22 12.5 2.0 17 6.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ67345.1 - 0.31 10.6 22.3 1.7 8.2 9.9 2.2 2 0 0 2 2 2 0 Spt20 family DUF4746 PF15928.5 CDJ67345.1 - 0.48 9.8 4.1 0.13 11.7 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) AAA_28 PF13521.6 CDJ67345.1 - 0.49 10.6 0.0 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain CITED PF04487.12 CDJ67345.1 - 0.69 9.9 7.3 0.095 12.8 0.6 2.2 2 0 0 2 2 2 0 CITED SUIM_assoc PF16619.5 CDJ67345.1 - 1.6 8.9 27.6 1.4 9.0 7.5 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ67346.1 - 0.45 10.5 77.3 0.093 12.7 63.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 CDJ67346.1 - 0.82 7.9 30.8 1.1 7.4 30.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 CDJ67346.1 - 3.2 7.2 41.8 6.9 6.1 41.8 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist O-antigen_lig PF13425.6 CDJ67346.1 - 3.8 6.2 7.5 5.6 5.6 7.5 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Caldesmon PF02029.15 CDJ67346.1 - 5.7 5.6 30.6 8 5.1 30.6 1.1 1 0 0 1 1 1 0 Caldesmon ECH_1 PF00378.20 CDJ67348.1 - 2e-23 83.0 0.0 2.5e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ67348.1 - 2.5e-07 30.5 0.0 3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase V-ATPase_C PF03223.15 CDJ67349.1 - 1.4e-69 235.3 0.0 1.6e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit C RskA PF10099.9 CDJ67350.1 - 0.0038 17.6 12.8 0.023 15.0 10.8 2.6 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Nha1_C PF08619.10 CDJ67350.1 - 0.057 12.6 12.9 0.085 12.1 12.9 1.3 1 1 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus CbiM PF01891.16 CDJ67350.1 - 0.59 9.9 2.3 0.48 10.2 0.7 1.6 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region FSA_C PF10479.9 CDJ67350.1 - 1.7 6.6 18.2 2.3 6.3 18.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PBP1_TM PF14812.6 CDJ67351.1 - 0.045 14.1 2.4 0.07 13.5 2.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PA26 PF04636.13 CDJ67351.1 - 0.07 12.0 1.7 0.08 11.8 1.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Cellulose_synt PF03552.14 CDJ67351.1 - 0.11 11.0 0.6 0.13 10.7 0.6 1.0 1 0 0 1 1 1 0 Cellulose synthase Ribosomal_60s PF00428.19 CDJ67351.1 - 0.13 12.9 11.9 0.16 12.6 0.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein K_channel_TID PF07941.11 CDJ67351.1 - 0.15 12.6 0.5 0.15 12.6 0.5 3.1 2 1 0 2 2 1 0 Potassium channel Kv1.4 tandem inactivation domain GNAT_like PF18407.1 CDJ67351.1 - 0.29 11.5 8.1 2.1 8.8 1.1 2.3 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain Roughex PF06020.11 CDJ67351.1 - 0.5 9.4 6.0 0.61 9.1 6.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Apt1 PF10351.9 CDJ67351.1 - 1.7 7.4 12.0 2.1 7.1 12.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.15 CDJ67351.1 - 3 7.3 9.4 3.8 7.0 9.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CDJ67351.1 - 3.1 7.4 12.3 4 7.0 12.3 1.2 1 0 0 1 1 1 0 Spt20 family GREB1 PF15782.5 CDJ67351.1 - 3.5 4.6 12.3 4.3 4.3 12.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 CDJ67351.1 - 6.2 5.2 12.9 7.1 5.0 12.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 MASE2 PF05230.11 CDJ67352.1 - 0.078 13.1 0.1 0.38 10.8 0.1 2.2 1 0 0 1 1 1 0 MASE2 domain RskA PF10099.9 CDJ67352.1 - 0.12 12.7 0.1 0.12 12.7 0.1 7.3 2 1 3 6 6 6 0 Anti-sigma-K factor rskA IMUP PF15761.5 CDJ67352.1 - 0.73 10.6 12.3 0.49 11.1 3.2 3.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein tRNA-synt_1e PF01406.19 CDJ67353.1 - 1.9e-12 47.1 0.0 2.6e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain RskA PF10099.9 CDJ67353.1 - 0.024 14.9 13.7 0.031 14.6 13.7 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Dehydrin PF00257.19 CDJ67353.1 - 0.12 12.9 8.4 0.13 12.8 8.4 1.1 1 0 0 1 1 1 0 Dehydrin DUF5542 PF17696.1 CDJ67353.1 - 0.21 11.7 5.2 0.36 11.0 5.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5542) BAF1_ABF1 PF04684.13 CDJ67353.1 - 0.48 9.4 3.2 0.51 9.3 3.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor K_channel_TID PF07941.11 CDJ67353.1 - 6.4 7.3 27.7 0.068 13.6 16.8 2.1 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-NF-X1 PF01422.17 CDJ67354.1 - 0.12 12.4 1.8 0.21 11.7 1.8 1.3 1 0 0 1 1 1 0 NF-X1 type zinc finger CLTH PF10607.9 CDJ67357.1 - 9.2e-21 74.3 0.1 1.6e-20 73.5 0.0 1.4 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CDJ67357.1 - 1.3e-05 25.0 0.2 2.4e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 LisH BTB PF00651.31 CDJ67359.1 - 3.4e-14 53.0 0.2 7.8e-14 51.8 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain Dus PF01207.17 CDJ67361.1 - 1.5e-46 158.9 0.0 1.2e-38 133.0 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Ribosomal_S13 PF00416.22 CDJ67362.1 - 8.1 6.9 9.9 2.4 8.5 5.3 2.4 2 1 1 3 3 3 0 Ribosomal protein S13/S18 Met_10 PF02475.16 CDJ67363.1 - 3.4e-47 160.8 0.0 4.5e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 CDJ67363.1 - 0.00062 19.0 0.1 0.00092 18.5 0.1 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_25 PF13649.6 CDJ67363.1 - 0.009 16.7 0.1 0.022 15.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CDJ67363.1 - 0.011 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.15 CDJ67363.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase SAM_MT PF04445.13 CDJ67363.1 - 0.044 13.2 0.1 0.076 12.4 0.1 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Hydin_ADK PF17213.3 CDJ67363.1 - 0.09 13.0 0.1 2 8.7 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain US22 PF02393.16 CDJ67363.1 - 0.093 13.0 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 US22 like DUF2600 PF10776.9 CDJ67364.1 - 0.015 14.2 1.2 0.025 13.5 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) DUF4062 PF13271.6 CDJ67364.1 - 0.025 15.0 0.4 0.09 13.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) UPF0242 PF06785.11 CDJ67364.1 - 0.059 13.5 3.4 1.2 9.2 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus gpW PF02831.15 CDJ67364.1 - 0.072 13.0 0.1 0.51 10.3 0.1 2.4 2 0 0 2 2 2 0 gpW Orai-1 PF07856.12 CDJ67364.1 - 0.11 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity NPV_P10 PF05531.12 CDJ67364.1 - 1.8 9.1 3.4 51 4.4 0.1 3.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Cpn60_TCP1 PF00118.24 CDJ67366.1 - 3.3e-23 82.1 0.0 3.4e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RskA PF10099.9 CDJ67367.1 - 0.39 11.0 12.2 0.53 10.5 12.2 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ67367.1 - 1.1 7.9 3.3 1.2 7.8 3.3 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_60s PF00428.19 CDJ67367.1 - 2.3 8.8 10.8 0.36 11.4 1.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Surface_antigen PF11054.8 CDJ67368.1 - 2.3e-06 27.5 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Hydrolase PF00702.26 CDJ67369.1 - 3e-10 40.7 2.8 2.1e-06 28.2 0.0 2.6 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ67369.1 - 0.045 13.9 0.2 0.35 11.0 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase APS_kinase PF01583.20 CDJ67369.1 - 0.053 13.4 0.3 4.9 7.0 0.0 3.1 2 1 0 2 2 2 0 Adenylylsulphate kinase CCDC53 PF10152.9 CDJ67369.1 - 0.23 11.9 2.9 0.6 10.5 2.9 1.6 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3138 PF11336.8 CDJ67369.1 - 1.4 7.4 8.3 1.9 7.0 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PDEase_I PF00233.19 CDJ67370.1 - 1.1e-39 136.5 0.3 1.5e-39 136.2 0.3 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ATP-gua_Ptrans PF00217.19 CDJ67370.1 - 0.052 13.0 0.1 0.084 12.3 0.1 1.4 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain Dpy19 PF10034.9 CDJ67371.1 - 5.1e-74 249.7 0.8 3e-29 101.8 0.0 4.0 1 1 3 4 4 4 4 Q-cell neuroblast polarisation Glyoxalase PF00903.25 CDJ67372.1 - 1e-33 116.2 0.0 7.9e-16 58.4 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CDJ67372.1 - 3.3e-13 49.8 0.0 3.8e-05 23.9 0.0 3.2 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 CDJ67372.1 - 4.9e-07 30.5 0.0 0.0036 18.1 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 CDJ67372.1 - 4.1e-05 23.8 0.0 0.0056 16.8 0.0 2.4 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 CDJ67372.1 - 0.0001 22.2 0.0 0.69 9.9 0.0 3.9 4 0 0 4 4 4 1 Glyoxalase-like domain CppA_N PF14506.6 CDJ67372.1 - 0.005 16.9 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal DUF3081 PF11280.8 CDJ67372.1 - 0.052 13.4 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) CPW_WPC PF09717.10 CDJ67373.1 - 2e-05 25.5 8.8 0.052 14.5 0.3 3.8 4 1 1 5 5 5 3 Plasmodium falciparum domain of unknown function (CPW_WPC) Nodulin_late PF07127.11 CDJ67373.1 - 0.58 10.5 2.9 9.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Late nodulin protein RAP PF08373.10 CDJ67374.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 RAP domain PTPLA PF04387.14 CDJ67375.1 - 7.5e-53 178.6 10.1 1.2e-52 178.0 10.1 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DivIC PF04977.15 CDJ67376.1 - 0.03 14.1 0.9 0.072 12.9 0.9 1.6 1 0 0 1 1 1 0 Septum formation initiator WD40 PF00400.32 CDJ67378.1 - 1.2e-36 124.0 25.7 1.3e-08 35.3 0.1 8.9 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ67378.1 - 8e-10 38.9 0.0 0.0022 18.3 0.0 5.0 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ67378.1 - 1.7e-06 27.0 2.5 0.23 10.0 0.0 4.0 3 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CDJ67378.1 - 0.0006 18.9 2.1 1.8 7.5 0.4 3.5 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 CDJ67378.1 - 0.0039 16.0 0.1 0.24 10.1 0.0 2.7 2 1 1 3 3 3 1 Nup133 N terminal like Lipase_3 PF01764.25 CDJ67379.1 - 4.2e-16 59.1 0.0 1.1e-15 57.7 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ67379.1 - 0.0057 17.3 0.5 0.037 14.6 0.0 2.4 1 1 2 3 3 3 1 Alpha/beta hydrolase family Spc7 PF08317.11 CDJ67380.1 - 0.00072 18.5 27.1 0.00089 18.2 27.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein V_ATPase_I PF01496.19 CDJ67380.1 - 0.016 13.1 19.8 0.02 12.8 19.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Dam1 PF08653.10 CDJ67380.1 - 0.054 13.3 5.9 3 7.7 0.9 3.1 1 1 1 2 2 2 0 DASH complex subunit Dam1 DUF4407 PF14362.6 CDJ67380.1 - 0.11 11.9 29.1 0.14 11.5 29.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 CDJ67380.1 - 0.13 12.7 1.1 5.7 7.4 0.0 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 CDJ67380.1 - 0.92 9.0 31.2 1.3 8.5 31.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc24 PF08286.11 CDJ67380.1 - 1.6 9.0 26.3 1.7 9.0 10.3 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF2730 PF10805.8 CDJ67380.1 - 1.8 8.7 17.2 5.5 7.1 15.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) HOOK PF05622.12 CDJ67380.1 - 1.9 6.5 35.3 2.3 6.3 35.3 1.0 1 0 0 1 1 1 0 HOOK protein Atg14 PF10186.9 CDJ67380.1 - 2.5 7.1 28.9 2.9 6.9 28.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fmp27_WPPW PF10359.9 CDJ67380.1 - 3.2 6.5 22.3 3.9 6.2 22.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain AcylCoA_dehyd_C PF12186.8 CDJ67380.1 - 3.8 7.7 6.8 13 6.0 0.6 2.5 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal YabA PF06156.13 CDJ67380.1 - 5.8 7.6 24.4 3.4 8.4 12.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Allexi_40kDa PF05549.11 CDJ67380.1 - 5.9 6.3 21.7 1.7 8.1 9.2 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.12 CDJ67380.1 - 8.4 6.4 15.6 1.7 8.7 9.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GrpE PF01025.19 CDJ67380.1 - 8.9 6.0 23.2 9.1 5.9 9.7 2.2 1 1 1 2 2 2 0 GrpE Casc1_N PF15927.5 CDJ67380.1 - 9.1 5.9 17.9 2.7 7.6 4.5 2.7 1 1 2 3 3 3 0 Cancer susceptibility candidate 1 N-terminus DUF755 PF05501.11 CDJ67381.1 - 0.013 15.8 14.5 0.015 15.6 14.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4667 PF15700.5 CDJ67381.1 - 0.092 12.8 11.1 0.1 12.7 11.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ67381.1 - 0.28 10.7 27.2 0.34 10.5 27.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_pol_Rpc4 PF05132.14 CDJ67381.1 - 0.67 10.4 5.1 0.78 10.2 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4228 PF14009.6 CDJ67381.1 - 2.1 8.7 10.2 2.3 8.6 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) IHABP4_N PF16174.5 CDJ67381.1 - 4.3 7.9 6.9 5 7.7 6.9 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4692 PF15763.5 CDJ67381.1 - 4.5 7.7 13.5 5.3 7.5 13.5 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) AF-4 PF05110.13 CDJ67381.1 - 4.7 5.2 25.0 5.1 5.0 25.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RskA PF10099.9 CDJ67381.1 - 4.7 7.5 22.3 5.3 7.3 22.3 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA GREB1 PF15782.5 CDJ67381.1 - 5.5 4.0 8.1 5.5 4.0 8.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RIFIN PF02009.16 CDJ67381.1 - 9 6.1 6.8 10 5.9 6.8 1.1 1 0 0 1 1 1 0 Rifin DUF945 PF06097.11 CDJ67382.1 - 0.68 9.0 8.1 1.6 7.7 8.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Kinesin PF00225.23 CDJ67383.1 - 4.2e-80 269.2 5.3 1.5e-79 267.4 5.3 1.9 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ67383.1 - 7.2e-21 74.7 0.0 4.9e-19 68.7 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding CCSAP PF15748.5 CDJ67384.1 - 0.0024 18.1 0.8 0.0036 17.5 0.8 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated Collagen PF01391.18 CDJ67384.1 - 0.079 12.7 36.7 0.09 12.5 32.8 3.2 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) CDK2AP PF09806.9 CDJ67384.1 - 0.18 11.8 9.4 0.32 11.0 9.4 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1216 PF06746.11 CDJ67384.1 - 0.7 9.9 4.8 1.4 8.9 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) DUF755 PF05501.11 CDJ67384.1 - 3.1 8.1 15.8 6 7.2 15.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ67384.1 - 5.4 6.6 18.4 0.15 11.6 12.2 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 CDJ67384.1 - 9.1 4.6 5.2 12 4.2 5.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Isy1 PF06246.12 CDJ67385.1 - 3.2e-31 108.8 7.9 3.9e-31 108.6 7.9 1.1 1 0 0 1 1 1 1 Isy1-like splicing family BAF1_ABF1 PF04684.13 CDJ67385.1 - 0.37 9.8 10.3 0.54 9.2 10.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Phage_Gp23 PF10669.9 CDJ67385.1 - 0.54 10.6 5.1 0.43 10.9 1.0 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Cob_adeno_trans PF01923.18 CDJ67385.1 - 0.71 10.0 7.8 0.99 9.5 7.8 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase CDK2AP PF09806.9 CDJ67385.1 - 3.8 7.5 17.4 5.8 6.9 17.4 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3676 PF12429.8 CDJ67385.1 - 4.7 7.0 13.5 6.4 6.5 13.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3676) SUIM_assoc PF16619.5 CDJ67385.1 - 6 7.0 20.7 8.3e+03 -3.0 20.7 2.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CDJ67385.1 - 7.8 7.2 34.0 0.72 10.5 10.4 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein RVP_2 PF08284.11 CDJ67386.1 - 1.7e-11 44.0 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ67386.1 - 1.7e-10 41.4 0.0 5.3e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ67386.1 - 2e-09 37.9 0.0 4.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ67386.1 - 0.00022 21.0 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ67386.1 - 0.00055 20.2 0.0 0.003 17.8 0.0 2.3 1 1 0 1 1 1 1 Retroviral aspartyl protease DUF3552 PF12072.8 CDJ67386.1 - 0.015 14.7 0.2 0.026 13.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1758 PF05585.12 CDJ67386.1 - 0.054 13.3 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-CCHC PF00098.23 CDJ67387.1 - 7.3e-08 32.1 12.9 2.3e-06 27.4 2.8 2.5 2 0 0 2 2 2 2 Zinc knuckle Retrotrans_gag PF03732.17 CDJ67387.1 - 5.1e-05 23.5 0.1 0.00025 21.3 0.0 2.1 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC_6 PF15288.6 CDJ67387.1 - 0.0016 18.2 0.4 0.0016 18.2 0.4 2.9 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ67387.1 - 0.0032 17.4 0.5 0.0032 17.4 0.5 2.4 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ67387.1 - 0.034 14.0 1.5 0.034 14.0 1.5 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ67387.1 - 0.24 11.2 5.2 0.97 9.2 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CDJ67387.1 - 1.1 9.7 11.4 2.8 8.4 11.4 1.7 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_5 PF14787.6 CDJ67387.1 - 1.5 8.6 10.8 3 7.6 2.3 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger ETRAMP PF09716.10 CDJ67388.1 - 0.00019 21.5 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Abhydrolase_4 PF08386.10 CDJ67388.1 - 1.2 9.3 10.5 0.06 13.5 1.2 2.7 3 0 0 3 3 3 0 TAP-like protein DUF4778 PF16008.5 CDJ67388.1 - 2.9 7.9 9.8 5.4 7.0 9.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4778) SUIM_assoc PF16619.5 CDJ67388.1 - 4.6 7.4 48.7 0.52 10.4 10.1 3.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Trp_oprn_chp PF09534.10 CDJ67388.1 - 7.3 6.3 14.0 2.4 7.9 8.9 2.2 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2722 PF10846.8 CDJ67388.1 - 7.8 5.3 29.1 0.64 8.9 3.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) TPR_9 PF13371.6 CDJ67391.1 - 2.4e-09 37.2 5.1 1.5e-08 34.6 0.1 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ67391.1 - 5.7e-06 26.0 3.6 0.21 11.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ67391.1 - 1e-05 25.9 0.9 1e-05 25.9 0.9 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ67391.1 - 0.00022 21.8 1.6 0.006 17.3 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ67391.1 - 0.00028 20.6 0.3 0.026 14.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ67391.1 - 0.0033 17.5 0.2 0.11 12.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ67391.1 - 0.0033 18.0 0.2 0.0033 18.0 0.2 3.4 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ67391.1 - 0.0084 16.7 3.5 0.2 12.4 0.1 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ67391.1 - 0.014 15.7 0.9 0.058 13.7 0.9 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ67391.1 - 0.016 15.4 3.2 0.03 14.6 1.7 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CDJ67391.1 - 0.023 15.1 0.6 0.08 13.4 0.6 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ67391.1 - 0.056 13.5 0.1 12 6.1 0.0 2.7 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 CDJ67391.1 - 0.056 14.1 4.4 0.26 12.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_2 PF02230.16 CDJ67392.1 - 3.4e-48 164.3 0.0 6.3e-48 163.4 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CDJ67392.1 - 9.6e-06 26.3 0.6 2.8e-05 24.8 0.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 CDJ67392.1 - 0.0018 17.8 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 CDJ67392.1 - 0.0024 17.2 1.0 0.42 9.8 0.2 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ67392.1 - 0.0047 16.6 0.0 0.063 12.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CDJ67392.1 - 0.0072 16.2 0.0 0.018 14.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 CDJ67392.1 - 0.0083 15.8 0.0 0.038 13.6 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF2920 PF11144.8 CDJ67392.1 - 0.065 12.4 0.1 0.14 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 CDJ67392.1 - 0.095 12.2 0.1 4.4 6.7 0.0 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family SET PF00856.28 CDJ67393.1 - 1e-05 26.0 0.0 9.2e-05 22.9 0.0 2.5 2 1 0 2 2 2 1 SET domain Se-cys_synth_N PF12390.8 CDJ67393.1 - 0.65 10.3 4.3 0.2 11.9 0.4 2.4 2 0 0 2 2 2 0 Selenocysteine synthase N terminal SKIP_SNW PF02731.15 CDJ67394.1 - 5.9e-69 230.8 1.3 5.9e-69 230.8 1.3 2.7 3 0 0 3 3 3 1 SKIP/SNW domain DNA_pol_A PF00476.20 CDJ67396.1 - 1.4e-75 254.7 0.0 9.9e-51 172.9 0.0 3.4 2 1 0 2 2 2 2 DNA polymerase family A 5_3_exonuc PF01367.20 CDJ67396.1 - 3.8e-11 43.4 0.0 1.1e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 CDJ67396.1 - 0.051 13.5 0.4 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain MMM1 PF10296.9 CDJ67396.1 - 0.29 10.2 3.5 0.38 9.8 0.0 2.6 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 MecA PF05389.12 CDJ67396.1 - 0.34 10.5 8.4 0.42 10.2 0.1 3.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Thg1C PF14413.6 CDJ67396.1 - 4.6 7.4 8.3 10 6.3 0.0 3.1 2 0 0 2 2 2 0 Thg1 C terminal domain eIF-3_zeta PF05091.12 CDJ67396.1 - 9.5 5.1 13.0 3.9 6.3 1.5 2.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RT_RNaseH PF17917.1 CDJ67397.1 - 9.3e-29 99.8 0.0 1.8e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ67397.1 - 3.5e-28 97.6 0.0 6.5e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ67397.1 - 0.00099 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ArabFuran-catal PF09206.11 CDJ67397.1 - 0.04 13.2 0.1 8.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase B, catalytic Chromo PF00385.24 CDJ67398.1 - 2.6e-12 46.4 0.0 4.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Myosin_head PF00063.21 CDJ67400.1 - 9e-14 50.6 0.0 1.2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) SR-25 PF10500.9 CDJ67401.1 - 0.0075 15.9 9.2 0.0081 15.8 9.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CDJ67401.1 - 0.01 16.4 5.5 0.01 16.4 5.5 1.8 1 1 1 2 2 2 0 Dehydrin Collagen PF01391.18 CDJ67402.1 - 4e-06 26.5 26.5 4e-06 26.5 26.5 7.6 4 2 1 5 5 5 2 Collagen triple helix repeat (20 copies) Nop53 PF07767.11 CDJ67403.1 - 1.2e-25 90.7 43.8 7.5e-25 88.1 43.8 2.0 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) SR-25 PF10500.9 CDJ67403.1 - 0.011 15.4 16.1 0.011 15.4 16.1 3.6 2 2 1 3 3 3 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ67403.1 - 2.5 8.8 47.8 0.075 13.7 11.3 4.7 5 0 0 5 5 5 0 Immortalisation up-regulated protein DUF3446 PF11928.8 CDJ67403.1 - 7.9 6.9 35.3 1.2 9.4 9.0 3.6 3 1 0 3 3 3 0 Early growth response N-terminal domain La PF05383.17 CDJ67404.1 - 2e-11 43.8 0.0 3e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 La domain Coilin_N PF15862.5 CDJ67404.1 - 0.00045 20.0 5.2 0.00045 20.0 5.2 7.9 7 2 1 8 8 8 2 Coilin N-terminus Peptidase_C12 PF01088.21 CDJ67405.1 - 1.9e-26 93.1 0.1 1.9e-26 93.1 0.1 4.1 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SR-25 PF10500.9 CDJ67405.1 - 0.00098 18.8 7.2 0.00098 18.8 7.2 3.0 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF3417 PF11897.8 CDJ67405.1 - 0.39 11.2 0.1 0.39 11.2 0.1 3.5 3 2 0 3 3 3 0 Protein of unknown function (DUF3417) E1-E2_ATPase PF00122.20 CDJ67406.1 - 7.1e-16 58.2 0.2 7.1e-16 58.2 0.2 4.6 3 2 1 5 5 5 2 E1-E2 ATPase Hydrolase PF00702.26 CDJ67406.1 - 4.8e-10 40.1 24.7 4.8e-10 40.1 24.7 3.7 3 2 0 3 3 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CDJ67406.1 - 2.3e-09 37.5 0.1 5.8e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 Heavy-metal-associated domain DUF4667 PF15700.5 CDJ67406.1 - 0.0057 16.8 14.0 0.053 13.6 0.1 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4667) DUF5341 PF17276.2 CDJ67406.1 - 0.22 11.7 3.6 0.38 10.9 3.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5341) Folliculin PF11704.8 CDJ67406.1 - 0.41 10.5 10.1 2.8 7.8 6.4 2.7 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport PIP5K PF01504.18 CDJ67406.1 - 0.59 9.3 4.1 3.5 6.8 3.6 2.0 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase RR_TM4-6 PF06459.12 CDJ67406.1 - 0.86 9.4 5.1 1.7 8.4 5.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hydrolase_3 PF08282.12 CDJ67406.1 - 1.3 8.7 6.2 1.7 8.3 0.7 2.7 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase DUF2052 PF09747.9 CDJ67406.1 - 1.4 9.0 9.3 3.1 7.9 9.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Bul1_C PF04426.12 CDJ67406.1 - 2.1 7.7 12.9 11 5.4 0.2 2.2 2 0 0 2 2 2 0 Bul1 C terminus V_ATPase_I PF01496.19 CDJ67406.1 - 2.1 6.2 5.4 3.7 5.4 5.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 CDJ67406.1 - 3 6.6 5.1 5 5.9 5.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Pox_Rap94 PF03294.14 CDJ67407.1 - 3.6 5.6 8.1 5.1 5.1 8.1 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 Methyltransf_5 PF01795.19 CDJ67408.1 - 0.005 16.4 0.0 0.017 14.7 0.0 1.8 1 1 0 1 1 1 1 MraW methylase family DUF2722 PF10846.8 CDJ67408.1 - 0.017 14.1 8.4 0.022 13.7 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ67408.1 - 0.069 13.1 11.2 0.083 12.9 11.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ67408.1 - 0.5 10.3 3.5 0.62 10.0 3.5 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med3 PF11593.8 CDJ67408.1 - 0.86 8.7 20.1 1.2 8.3 20.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CDK2AP PF09806.9 CDJ67408.1 - 1.5 8.9 9.6 2.2 8.3 9.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Roughex PF06020.11 CDJ67408.1 - 2 7.4 4.6 2.4 7.2 4.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF4834 PF16118.5 CDJ67408.1 - 2.5 9.1 5.7 3.6 8.6 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) UPF0560 PF10577.9 CDJ67408.1 - 3.5 6.0 6.6 4.6 5.6 6.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Spt20 PF12090.8 CDJ67408.1 - 4.7 6.8 20.2 6.2 6.4 20.2 1.0 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ67409.1 - 0.0016 18.1 1.2 0.0016 18.1 1.2 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ67409.1 - 0.058 13.5 10.2 1.6 8.8 4.0 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MAGE_N PF12440.8 CDJ67409.1 - 0.61 10.8 17.6 0.04 14.6 9.4 2.2 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal IMUP PF15761.5 CDJ67409.1 - 1.1 10.0 8.3 1.9 9.2 7.4 1.8 1 1 1 2 2 2 0 Immortalisation up-regulated protein E3_UFM1_ligase PF09743.9 CDJ67410.1 - 5e-16 59.1 0.2 5.4e-16 59.0 0.2 1.0 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 BAF1_ABF1 PF04684.13 CDJ67411.1 - 9.5 5.1 35.8 10 5.0 35.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SPX PF03105.19 CDJ67413.1 - 0.056 13.4 0.0 3.9 7.3 0.0 2.3 2 0 0 2 2 2 0 SPX domain DUF3531 PF12049.8 CDJ67413.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) Wzy_C PF04932.15 CDJ67413.1 - 0.91 9.1 7.2 0.035 13.8 0.8 1.9 2 0 0 2 2 2 0 O-Antigen ligase BBS2_C PF14782.6 CDJ67413.1 - 1.5 7.5 4.4 2.1 7.0 4.4 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal ABC_tran PF00005.27 CDJ67414.1 - 1.3e-48 165.0 0.0 2.5e-26 92.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDJ67414.1 - 8.8e-34 117.1 30.9 1.2e-28 100.3 1.7 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ67414.1 - 8.9e-16 58.6 0.7 1.1e-05 25.4 0.0 4.5 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ67414.1 - 1.2e-05 24.9 1.0 0.075 12.8 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ67414.1 - 0.00014 21.8 0.5 0.026 14.4 0.1 3.2 3 0 0 3 3 3 1 RsgA GTPase AAA_23 PF13476.6 CDJ67414.1 - 0.00081 19.9 3.2 0.024 15.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 CDJ67414.1 - 0.022 14.2 0.3 23 4.4 0.1 3.5 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 CDJ67414.1 - 0.024 15.3 0.1 2.6 8.8 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4162) SRP54 PF00448.22 CDJ67414.1 - 0.028 14.0 1.1 0.14 11.7 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CDJ67414.1 - 0.041 13.2 0.1 0.32 10.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 CDJ67414.1 - 0.049 13.4 0.1 14 5.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ67414.1 - 0.066 13.6 0.1 12 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain DUF4658 PF15555.6 CDJ67414.1 - 0.078 13.1 1.5 14 5.8 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4658) DUF87 PF01935.17 CDJ67414.1 - 0.14 12.2 3.1 2.8 8.0 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 CDJ67414.1 - 0.26 11.4 5.1 0.44 10.6 0.7 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase MeaB PF03308.16 CDJ67414.1 - 0.77 8.7 4.2 1.7 7.6 0.3 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 CDJ67414.1 - 1.4 8.8 3.4 2.7 7.9 0.1 2.8 3 0 0 3 3 3 0 NTPase Chorion_2 PF03964.15 CDJ67416.1 - 0.88 10.4 28.7 0.32 11.9 1.7 3.5 3 0 0 3 3 3 0 Chorion family 2 Spt20 PF12090.8 CDJ67416.1 - 4.5 6.8 6.9 6.8 6.2 6.9 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ67416.1 - 6.1 6.7 8.9 0.5 10.3 4.1 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IMP2_N PF18590.1 CDJ67417.1 - 3.1e-12 46.9 0.0 3.1e-12 46.9 0.0 1.7 2 0 0 2 2 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain CDC45 PF02724.14 CDJ67417.1 - 0.082 11.2 8.9 0.094 11.0 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ67417.1 - 0.09 11.5 14.5 0.1 11.3 14.5 1.2 1 0 0 1 1 1 0 Presenilin SMYLE_N PF18615.1 CDJ67417.1 - 0.1 12.2 8.5 0.11 12.0 8.5 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF5523 PF17661.1 CDJ67417.1 - 0.12 12.0 13.4 0.18 11.4 13.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Med15 PF09606.10 CDJ67417.1 - 0.25 10.0 31.0 0.34 9.6 31.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hamartin PF04388.12 CDJ67417.1 - 0.54 8.8 9.7 0.59 8.7 9.7 1.1 1 0 0 1 1 1 0 Hamartin protein MMR1 PF08505.10 CDJ67417.1 - 0.63 10.3 13.7 0.77 10.0 13.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SOBP PF15279.6 CDJ67417.1 - 0.64 10.6 9.5 0.8 10.3 9.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S64 PF08192.11 CDJ67417.1 - 0.7 8.3 7.1 0.73 8.3 7.1 1.2 1 0 0 1 1 1 0 Peptidase family S64 Lin-8 PF03353.15 CDJ67417.1 - 0.8 9.2 12.8 1.1 8.8 12.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PIP5K PF01504.18 CDJ67417.1 - 0.9 8.7 4.7 1.1 8.4 4.7 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase GREB1 PF15782.5 CDJ67417.1 - 0.96 6.5 17.4 1.1 6.3 17.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ67417.1 - 0.98 7.6 23.4 1 7.5 23.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.9 CDJ67417.1 - 1.1 7.7 11.6 1.3 7.5 11.6 1.1 1 0 0 1 1 1 0 Macoilin family eIF-3_zeta PF05091.12 CDJ67417.1 - 1.2 8.0 13.0 1.6 7.6 13.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MID_MedPIWI PF18296.1 CDJ67417.1 - 1.4 8.7 11.4 1.9 8.2 11.4 1.3 1 0 0 1 1 1 0 MID domain of medPIWI Membralin PF09746.9 CDJ67417.1 - 1.5 7.8 2.9 1.7 7.6 2.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein NPR3 PF03666.13 CDJ67417.1 - 1.8 7.3 9.4 2.2 7.0 9.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 CDJ67417.1 - 2.2 7.2 10.8 2.9 6.8 10.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM60A PF15396.6 CDJ67417.1 - 2.2 8.2 9.7 3.3 7.6 9.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ67417.1 - 2.5 7.8 18.8 4.3 7.1 18.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 CDJ67417.1 - 3.3 7.4 6.3 4.3 7.0 6.3 1.3 1 0 0 1 1 1 0 Connexin GET2 PF08690.10 CDJ67417.1 - 3.5 7.2 16.1 4.8 6.8 16.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 RskA PF10099.9 CDJ67417.1 - 3.9 7.7 51.9 24 5.1 17.3 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF5521 PF17659.1 CDJ67417.1 - 3.9 5.2 12.0 4.4 5.0 12.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Endostatin PF06482.11 CDJ67417.1 - 4.2 6.8 11.7 5.9 6.3 11.7 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin EOS1 PF12326.8 CDJ67417.1 - 4.9 7.1 4.6 7.9 6.4 4.6 1.4 1 0 0 1 1 1 0 N-glycosylation protein Neur_chan_memb PF02932.16 CDJ67417.1 - 5.2 7.0 11.2 7.7 6.5 11.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4045 PF13254.6 CDJ67417.1 - 5.9 6.4 24.6 7.7 6.0 24.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Zip PF02535.22 CDJ67417.1 - 6.1 6.0 8.6 7.8 5.6 8.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0560 PF10577.9 CDJ67417.1 - 6.5 5.1 16.3 8 4.8 16.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Draxin PF15550.6 CDJ67417.1 - 6.7 6.5 12.4 9.7 6.0 12.4 1.2 1 0 0 1 1 1 0 Draxin SLC12 PF03522.15 CDJ67417.1 - 8.4 5.3 13.3 11 4.9 13.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RNase_PH PF01138.21 CDJ67418.1 - 3.6e-10 40.4 0.0 6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDJ67418.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 KH_1 PF00013.29 CDJ67419.1 - 0.0082 16.0 0.0 0.92 9.4 0.0 2.6 2 0 0 2 2 2 2 KH domain VHS PF00790.19 CDJ67419.1 - 0.014 15.3 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 VHS domain zf-C2H2_4 PF13894.6 CDJ67420.1 - 9.9 7.3 9.2 2.6 9.1 3.8 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger UFC1 PF08694.11 CDJ67421.1 - 4.1e-77 257.1 0.1 4.7e-77 256.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 CDJ67421.1 - 0.0044 16.7 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ67421.1 - 0.021 15.1 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain Glyco_hydro_61 PF03443.14 CDJ67421.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 PAP_assoc PF03828.19 CDJ67422.1 - 3e-05 24.1 0.4 0.00085 19.5 0.2 2.8 3 0 0 3 3 3 1 Cid1 family poly A polymerase PHD20L1_u1 PF16660.5 CDJ67423.1 - 0.38 11.5 9.3 0.81 10.5 9.3 1.5 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 SRP-alpha_N PF04086.13 CDJ67423.1 - 1.3 8.9 5.4 1.7 8.5 5.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3275 PF11679.8 CDJ67423.1 - 3.3 7.6 6.0 5.3 7.0 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Exo_endo_phos PF03372.23 CDJ67424.1 - 2.5e-07 30.5 0.0 1.6e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Collagen PF01391.18 CDJ67425.1 - 0.11 12.2 19.4 0.35 10.7 19.4 1.8 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) PAT1 PF09770.9 CDJ67426.1 - 0.0055 15.1 36.0 0.0055 15.1 36.0 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.6 CDJ67426.1 - 0.016 15.7 25.1 0.022 15.3 25.1 1.3 1 0 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.12 CDJ67426.1 - 0.33 9.9 25.8 0.43 9.5 25.8 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2052 PF09747.9 CDJ67426.1 - 0.55 10.3 31.5 0.79 9.8 31.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TFIIA PF03153.13 CDJ67426.1 - 0.57 10.1 66.0 0.79 9.7 66.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 CDJ67426.1 - 1 9.5 37.6 1.9 8.6 37.6 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 CDJ67426.1 - 2.4 6.4 23.6 2.6 6.2 23.6 1.2 1 0 0 1 1 1 0 CDC45-like protein VIR_N PF15912.5 CDJ67426.1 - 4.2 6.9 16.9 5 6.7 16.9 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4746 PF15928.5 CDJ67426.1 - 4.3 6.7 25.3 5.5 6.3 25.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Asp-B-Hydro_N PF05279.11 CDJ67426.1 - 6.5 6.7 22.7 8.2 6.4 22.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2312 PF10073.9 CDJ67427.1 - 0.0075 15.9 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) DUF3206 PF11472.8 CDJ67427.1 - 0.072 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) DUF3273 PF11677.8 CDJ67428.1 - 4.6e-36 124.5 2.6 5.6e-36 124.2 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF2568 PF10823.8 CDJ67428.1 - 0.016 15.5 2.5 0.016 15.5 2.5 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2568) DUF3273 PF11677.8 CDJ67429.1 - 1.4e-45 155.7 7.7 1.6e-45 155.5 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) RskA PF10099.9 CDJ67430.1 - 0.87 9.9 22.5 1.2 9.4 22.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA FSA_C PF10479.9 CDJ67430.1 - 3.8 5.5 10.0 4.3 5.3 10.0 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Apt1 PF10351.9 CDJ67431.1 - 0.0062 15.5 2.7 0.0069 15.3 2.7 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain FAM199X PF15814.5 CDJ67431.1 - 0.012 14.7 12.0 0.019 14.0 12.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X DUF1635 PF07795.11 CDJ67431.1 - 0.019 14.8 9.8 0.026 14.4 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Macoilin PF09726.9 CDJ67431.1 - 0.022 13.4 4.1 0.023 13.3 4.1 1.1 1 0 0 1 1 1 0 Macoilin family CCDC24 PF15669.5 CDJ67431.1 - 0.032 14.1 8.6 0.048 13.5 8.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF755 PF05501.11 CDJ67431.1 - 0.061 13.6 23.5 0.093 13.0 23.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Lin-8 PF03353.15 CDJ67431.1 - 0.11 12.0 6.4 0.15 11.6 6.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Fmp27_WPPW PF10359.9 CDJ67431.1 - 0.12 11.2 3.2 0.16 10.8 3.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spt20 PF12090.8 CDJ67431.1 - 0.27 10.8 8.1 0.36 10.4 8.1 1.1 1 0 0 1 1 1 0 Spt20 family AF-4 PF05110.13 CDJ67431.1 - 0.28 9.2 22.4 0.33 9.0 22.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peroxin-3 PF04882.12 CDJ67431.1 - 0.35 9.8 10.5 0.46 9.4 10.5 1.1 1 0 0 1 1 1 0 Peroxin-3 GREB1 PF15782.5 CDJ67431.1 - 0.41 7.7 7.3 0.51 7.4 7.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Miga PF10265.9 CDJ67431.1 - 0.76 8.7 7.1 0.95 8.4 7.1 1.1 1 0 0 1 1 1 0 Mitoguardin DUF4667 PF15700.5 CDJ67431.1 - 0.97 9.5 14.7 1.3 9.1 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) GCOM2 PF15328.6 CDJ67431.1 - 1.2 9.5 7.2 1.6 9.0 7.2 1.1 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 LRRFIP PF09738.9 CDJ67431.1 - 1.3 8.4 9.0 1.7 8.1 9.0 1.1 1 0 0 1 1 1 0 LRRFIP family CCDC106 PF15794.5 CDJ67431.1 - 2.4 7.8 12.4 3.4 7.3 12.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Peptidase_S64 PF08192.11 CDJ67431.1 - 6.7 5.1 12.1 8.3 4.8 12.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 Sporozoite_P67 PF05642.11 CDJ67431.1 - 9.8 4.1 10.1 0.56 8.2 5.0 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RT_RNaseH PF17917.1 CDJ67432.1 - 3.8e-29 101.1 0.0 7.7e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ67432.1 - 4.5e-29 100.4 0.1 8.4e-29 99.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ67432.1 - 1.2e-21 77.2 0.0 2.3e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ67432.1 - 0.00067 19.7 1.6 0.0014 18.7 1.6 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ67432.1 - 0.025 14.7 0.1 0.075 13.2 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain UL11 PF11094.8 CDJ67432.1 - 0.049 13.5 0.0 16 5.5 0.0 2.8 3 0 0 3 3 3 0 Membrane-associated tegument protein RVT_3 PF13456.6 CDJ67432.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like RT_RNaseH PF17917.1 CDJ67434.1 - 6.4e-30 103.5 0.1 1e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ67434.1 - 1.3e-29 102.1 0.1 2.1e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ67434.1 - 6.5e-16 58.5 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 CDJ67434.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like Hydrolase_3 PF08282.12 CDJ67435.1 - 0.02 14.7 2.3 0.025 14.3 2.3 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Coilin_N PF15862.5 CDJ67436.1 - 0.14 12.0 16.6 0.14 11.9 16.6 1.2 1 0 0 1 1 1 0 Coilin N-terminus SpoIIP PF07454.11 CDJ67436.1 - 0.17 11.3 16.9 0.17 11.3 16.9 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 CDJ67436.1 - 0.18 11.5 11.3 0.19 11.5 11.3 1.1 1 0 0 1 1 1 0 Connexin CPSF100_C PF13299.6 CDJ67436.1 - 0.19 11.9 10.9 0.17 12.0 10.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 CDJ67436.1 - 0.2 11.4 13.5 0.19 11.5 13.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3408 PF11888.8 CDJ67436.1 - 0.2 11.8 14.0 0.19 11.8 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Presenilin PF01080.17 CDJ67436.1 - 0.21 10.3 17.0 0.18 10.5 17.0 1.0 1 0 0 1 1 1 0 Presenilin G0-G1_switch_2 PF15103.6 CDJ67436.1 - 0.26 11.7 11.4 0.3 11.5 11.4 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 TFB6 PF17110.5 CDJ67436.1 - 0.27 11.0 6.7 0.25 11.1 6.7 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Gti1_Pac2 PF09729.9 CDJ67436.1 - 0.28 11.3 11.3 0.27 11.3 11.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DNA_pol3_a_NII PF11490.8 CDJ67436.1 - 0.31 11.0 21.2 0.34 10.8 21.2 1.1 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Pex14_N PF04695.13 CDJ67436.1 - 0.47 11.1 28.0 0.48 11.1 28.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GNAT_acetyltr_2 PF13718.6 CDJ67436.1 - 0.5 9.7 9.3 0.54 9.6 9.3 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DDHD PF02862.17 CDJ67436.1 - 0.64 10.1 15.2 0.62 10.2 15.2 1.0 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.15 CDJ67436.1 - 0.65 8.9 9.6 0.62 8.9 9.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) FHIPEP PF00771.20 CDJ67436.1 - 0.89 7.9 8.4 0.94 7.9 8.4 1.1 1 0 0 1 1 1 0 FHIPEP family EIIBC-GUT_N PF03612.14 CDJ67436.1 - 0.93 9.2 13.6 0.92 9.2 13.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CCDC53 PF10152.9 CDJ67436.1 - 0.94 9.9 17.1 0.88 10.0 17.1 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SID-1_RNA_chan PF13965.6 CDJ67436.1 - 0.95 7.8 7.4 0.9 7.9 7.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Rxt3 PF08642.10 CDJ67436.1 - 1 10.2 8.6 1.1 10.0 8.6 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 eIF-3_zeta PF05091.12 CDJ67436.1 - 1.1 8.2 22.9 1 8.3 22.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ67436.1 - 1.1 7.1 15.7 1 7.2 15.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 CDJ67436.1 - 1.2 8.1 11.5 1.2 8.1 11.5 1.0 1 0 0 1 1 1 0 CLN3 protein Peroxin-13_N PF04088.13 CDJ67436.1 - 1.2 9.4 9.1 1.2 9.4 9.1 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region AAA_23 PF13476.6 CDJ67436.1 - 1.3 9.5 17.8 1.3 9.5 17.8 1.1 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 CDJ67436.1 - 1.5 8.1 16.3 1.3 8.3 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SLC12 PF03522.15 CDJ67436.1 - 1.6 7.7 14.7 1.5 7.7 14.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 CDJ67436.1 - 1.6 7.6 10.5 1.5 7.7 10.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DcuA_DcuB PF03605.14 CDJ67436.1 - 1.7 7.5 5.0 1.9 7.3 5.0 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Cellulose_synt PF03552.14 CDJ67436.1 - 1.7 7.0 7.9 1.6 7.1 7.9 1.0 1 0 0 1 1 1 0 Cellulose synthase MDM31_MDM32 PF08118.11 CDJ67436.1 - 1.9 7.1 10.2 1.7 7.2 10.2 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF4175 PF13779.6 CDJ67436.1 - 2.2 6.1 37.7 2.1 6.2 37.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF808 PF05661.12 CDJ67436.1 - 2.3 7.2 2.8 2.7 7.0 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Baculo_PP31 PF05311.11 CDJ67436.1 - 3.1 7.2 15.8 2.9 7.3 15.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Band_3_cyto PF07565.13 CDJ67436.1 - 3.1 7.5 16.3 3 7.6 16.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain EOS1 PF12326.8 CDJ67436.1 - 3.1 7.7 9.0 2.9 7.8 9.0 1.1 1 0 0 1 1 1 0 N-glycosylation protein TERB2 PF15101.6 CDJ67436.1 - 3.6 7.6 23.7 3.8 7.5 23.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TFIIA PF03153.13 CDJ67436.1 - 3.8 7.4 43.3 3.6 7.5 43.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CSG2 PF16965.5 CDJ67436.1 - 4.2 6.2 9.0 3.9 6.3 9.0 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator PAT1 PF09770.9 CDJ67436.1 - 4.7 5.4 29.6 4.2 5.5 29.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HA2 PF04408.23 CDJ67436.1 - 4.8 7.5 8.0 5.8 7.2 8.0 1.4 1 0 0 1 1 1 0 Helicase associated domain (HA2) Hid1 PF12722.7 CDJ67436.1 - 4.9 5.2 14.6 4.4 5.3 14.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1682 PF07946.14 CDJ67436.1 - 5 6.2 13.9 4.7 6.3 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AIF_C PF14721.6 CDJ67436.1 - 5.6 7.3 15.4 6.5 7.1 15.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Folate_carrier PF01770.18 CDJ67436.1 - 6.4 5.4 10.8 6.1 5.5 10.8 1.0 1 0 0 1 1 1 0 Reduced folate carrier Suf PF05843.14 CDJ67436.1 - 6.6 6.6 24.5 6.8 6.6 24.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ctr PF04145.15 CDJ67436.1 - 7.5 7.2 10.3 7.4 7.2 10.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Neur_chan_memb PF02932.16 CDJ67436.1 - 7.7 6.5 14.6 7.4 6.6 14.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM91_C PF14648.6 CDJ67436.1 - 7.9 5.2 11.8 8.2 5.1 11.8 1.1 1 0 0 1 1 1 0 FAM91 C-terminus PepSY_TM PF03929.16 CDJ67436.1 - 8.6 5.9 10.2 7.9 6.0 10.2 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Kei1 PF08552.11 CDJ67436.1 - 9.2 6.1 11.6 9.7 6.0 11.6 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1980 PF09323.10 CDJ67436.1 - 9.3 6.1 14.4 9.6 6.1 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) EMP24_GP25L PF01105.24 CDJ67437.1 - 1.8e-08 34.5 0.0 2.5e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribosomal_60s PF00428.19 CDJ67437.1 - 0.00063 20.3 12.2 0.00079 20.0 7.3 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein OAM_dimer PF16554.5 CDJ67437.1 - 1.9 9.0 0.0 1.9 9.0 0.0 2.8 3 0 0 3 3 3 0 Dimerisation domain of d-ornithine 4,5-aminomutase Macoilin PF09726.9 CDJ67438.1 - 0.0034 16.0 5.1 0.004 15.8 5.1 1.0 1 0 0 1 1 1 1 Macoilin family Remorin_C PF03763.13 CDJ67438.1 - 0.0051 16.7 3.5 0.0093 15.8 3.5 1.4 1 0 0 1 1 1 1 Remorin, C-terminal region Syntaxin_2 PF14523.6 CDJ67438.1 - 0.017 15.5 9.0 0.023 15.1 9.0 1.1 1 0 0 1 1 1 0 Syntaxin-like protein SOAR PF16533.5 CDJ67438.1 - 0.046 13.7 1.3 0.1 12.6 1.0 1.8 2 0 0 2 2 2 0 STIM1 Orai1-activating region CorA PF01544.18 CDJ67438.1 - 0.053 12.8 5.4 0.074 12.4 5.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Hom_end_hint PF05203.16 CDJ67438.1 - 0.22 11.4 1.3 0.28 11.1 1.3 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint HisKA_3 PF07730.13 CDJ67438.1 - 0.71 10.4 0.1 0.71 10.4 0.1 3.0 3 1 0 3 3 3 0 Histidine kinase Fib_alpha PF08702.10 CDJ67438.1 - 1.9 8.6 5.1 3.9 7.7 5.1 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family K_channel_TID PF07941.11 CDJ67438.1 - 2.2 8.8 11.2 4.5 7.8 11.2 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Spt20 PF12090.8 CDJ67440.1 - 0.0061 16.2 0.5 0.0061 16.2 0.5 1.5 2 0 0 2 2 2 1 Spt20 family Afi1 PF07792.12 CDJ67441.1 - 0.00014 22.3 0.0 0.00014 22.3 0.0 7.4 5 2 2 7 7 7 3 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_S49_N PF08496.10 CDJ67441.1 - 0.033 14.3 0.1 0.033 14.3 0.1 6.4 4 2 1 5 5 5 0 Peptidase family S49 N-terminal RskA PF10099.9 CDJ67441.1 - 0.18 12.1 0.0 0.18 12.1 0.0 9.1 3 2 2 5 5 5 0 Anti-sigma-K factor rskA Thioredoxin PF00085.20 CDJ67442.1 - 5.6e-56 186.9 0.1 2.3e-30 104.6 0.1 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CDJ67442.1 - 3.4e-22 79.2 0.0 2e-12 47.4 0.0 3.7 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CDJ67442.1 - 6.5e-10 39.4 2.0 0.00035 21.0 0.1 3.5 2 2 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CDJ67442.1 - 2.6e-09 36.9 0.4 0.00014 21.3 0.0 2.5 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CDJ67442.1 - 2.7e-09 37.1 5.2 0.0017 18.5 0.1 4.1 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CDJ67442.1 - 1.4e-07 31.8 0.1 0.032 14.6 0.0 3.5 3 1 1 4 4 4 2 Thioredoxin-like TraF PF13728.6 CDJ67442.1 - 2.3e-07 30.9 0.1 0.0049 16.7 0.0 2.5 2 0 0 2 2 2 2 F plasmid transfer operon protein AhpC-TSA PF00578.21 CDJ67442.1 - 2.9e-07 30.4 0.2 0.00041 20.3 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Calsequestrin PF01216.17 CDJ67442.1 - 5e-06 25.8 0.0 1.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Calsequestrin Redoxin PF08534.10 CDJ67442.1 - 6.9e-05 22.6 1.0 0.018 14.8 0.1 2.7 3 0 0 3 3 3 2 Redoxin ERp29_N PF07912.13 CDJ67442.1 - 0.0031 17.6 0.0 3.4 7.8 0.0 3.2 3 1 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_9 PF14595.6 CDJ67442.1 - 0.0079 16.0 0.0 1.9 8.3 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin NMD3 PF04981.13 CDJ67442.1 - 0.028 13.9 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 NMD3 family Glutaredoxin PF00462.24 CDJ67442.1 - 0.16 12.2 4.3 8.6 6.7 0.1 3.5 3 2 0 3 3 3 0 Glutaredoxin Dehydrin PF00257.19 CDJ67443.1 - 0.00071 20.2 18.1 0.00071 20.2 18.1 3.0 1 1 0 2 2 2 1 Dehydrin FGF-BP1 PF06473.12 CDJ67443.1 - 0.41 10.4 47.3 0.31 10.8 24.8 2.3 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) TCP PF03634.13 CDJ67443.1 - 2.1 8.9 52.6 0.13 12.8 12.2 2.2 2 0 0 2 2 2 0 TCP family transcription factor FAM60A PF15396.6 CDJ67443.1 - 3.2 7.7 42.5 2.6 8.0 24.8 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF4746 PF15928.5 CDJ67443.1 - 7.6 5.9 37.1 6.4 6.1 7.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CLN3 PF02487.17 CDJ67443.1 - 8.9 5.2 34.7 0.1 11.6 16.1 2.3 2 0 0 2 2 2 0 CLN3 protein DUF3437 PF11919.8 CDJ67444.1 - 2.5e-26 91.4 0.0 1.1e-25 89.3 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_mid PF16507.5 CDJ67444.1 - 2e-16 59.8 0.0 3.7e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Proteasome-substrate-size regulator, mid region Ribosomal_60s PF00428.19 CDJ67444.1 - 0.0062 17.1 1.2 0.0062 17.1 1.2 10.3 9 2 1 10 10 10 3 60s Acidic ribosomal protein KfrA_N PF11740.8 CDJ67444.1 - 0.021 15.5 0.9 0.021 15.5 0.9 11.4 8 4 2 10 10 10 0 Plasmid replication region DNA-binding N-term DUF4667 PF15700.5 CDJ67444.1 - 0.12 12.4 0.0 0.12 12.4 0.0 5.9 5 2 0 6 6 6 0 Domain of unknown function (DUF4667) IMUP PF15761.5 CDJ67444.1 - 2.3 9.0 66.6 0.31 11.8 6.1 6.1 5 0 0 5 5 5 0 Immortalisation up-regulated protein DEAD PF00270.29 CDJ67445.1 - 2.3e-16 60.1 0.0 2.7e-14 53.3 0.0 5.0 4 1 1 5 5 5 3 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ67445.1 - 2.3e-10 40.8 0.4 8.3e-09 35.8 0.4 3.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain EAR PF07897.11 CDJ67446.1 - 8.7 6.1 6.0 5.9 6.6 0.9 2.5 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression SUIM_assoc PF16619.5 CDJ67447.1 - 0.0089 16.1 10.5 0.0089 16.1 10.5 9.8 8 1 1 9 9 9 7 Unstructured region C-term to UIM in Ataxin3 Longin PF13774.6 CDJ67447.1 - 0.37 10.8 1.6 1.5 8.9 0.1 2.7 2 0 0 2 2 2 0 Regulated-SNARE-like domain EI24 PF07264.11 CDJ67448.1 - 7.7e-09 36.0 15.7 9.2e-05 22.8 14.2 3.2 2 1 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) SARAF PF06682.12 CDJ67448.1 - 0.0035 17.0 4.2 0.0035 17.0 4.2 4.5 3 1 2 5 5 5 1 SOCE-associated regulatory factor of calcium homoeostasis RAP1 PF07218.11 CDJ67448.1 - 0.54 8.5 6.2 0.035 12.4 0.6 1.7 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) GTP_EFTU_D2 PF03144.25 CDJ67449.1 - 0.00014 22.2 0.3 0.00028 21.2 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ribosomal_L2_C PF03947.18 CDJ67453.1 - 2.6e-43 147.2 3.1 6.2e-43 146.0 3.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CDJ67453.1 - 3.7e-18 65.3 0.1 8.6e-18 64.1 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TPR_1 PF00515.28 CDJ67454.1 - 0.00055 19.6 0.4 0.033 14.0 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF755 PF05501.11 CDJ67454.1 - 0.0047 17.2 3.8 0.0047 17.2 3.8 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF755) DUF4028 PF13220.6 CDJ67454.1 - 0.015 15.0 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) TPR_2 PF07719.17 CDJ67454.1 - 0.022 14.9 9.4 0.34 11.1 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ67454.1 - 0.24 11.5 2.8 0.2 11.7 0.4 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat CAML PF14963.6 CDJ67454.1 - 0.97 9.5 4.6 1.8 8.6 4.6 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF4834 PF16118.5 CDJ67454.1 - 4.9 8.2 5.3 17 6.4 5.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PIG-P PF08510.12 CDJ67455.1 - 7.2e-30 103.4 0.0 9.3e-30 103.0 0.0 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 CDJ67455.1 - 0.065 13.6 9.8 0.26 11.6 9.8 1.9 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Vma12 PF11712.8 CDJ67455.1 - 0.19 11.8 0.5 0.47 10.5 0.0 1.8 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cytochrome-c551 PF10643.9 CDJ67455.1 - 0.96 9.0 2.2 1.2 8.7 2.2 1.3 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 RCC1 PF00415.18 CDJ67456.1 - 5.5e-13 49.3 0.9 0.0011 19.5 0.0 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ67456.1 - 0.061 13.2 8.5 9.2 6.2 0.0 4.7 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CDJ67457.1 - 2.6e-18 66.4 1.1 2.8e-06 27.8 0.3 4.1 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ67457.1 - 1.3e-13 50.4 14.4 8.8e-09 34.9 1.4 3.2 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Aldo_ket_red PF00248.21 CDJ67459.1 - 4.3e-34 118.0 0.0 3.2e-32 111.9 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family SUI1 PF01253.22 CDJ67460.1 - 6.6e-16 58.6 0.0 1.3e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 zf-His_Me_endon PF05551.11 CDJ67461.1 - 0.043 14.0 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease AP2 PF00847.20 CDJ67462.1 - 0.00072 19.7 0.0 2.2 8.6 0.0 2.7 2 0 0 2 2 2 2 AP2 domain PhoLip_ATPase_C PF16212.5 CDJ67463.1 - 9.7e-45 153.3 22.2 9.7e-45 153.3 22.2 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDJ67463.1 - 2.7e-15 55.8 5.8 2.7e-15 55.8 5.8 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CDJ67463.1 - 3.4e-14 53.6 0.3 8.8e-08 32.7 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ67463.1 - 5.2e-10 39.3 0.0 3.1e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CDJ67463.1 - 0.0031 17.0 18.8 0.011 15.3 0.0 4.9 5 0 0 5 5 5 2 E1-E2 ATPase Hydrolase_3 PF08282.12 CDJ67463.1 - 0.0076 16.0 0.0 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ67463.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF1772 PF08592.11 CDJ67463.1 - 0.18 12.1 0.0 0.18 12.1 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) tRNA-synt_2b PF00587.25 CDJ67465.1 - 5.1e-31 108.0 0.0 3.7e-29 101.9 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CDJ67465.1 - 1.6e-21 76.3 0.1 3.9e-21 75.0 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 CDJ67465.1 - 2.9e-10 40.1 0.0 7.5e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 CDJ67465.1 - 7.2e-08 32.4 0.0 1e-06 28.7 0.0 2.8 2 1 0 2 2 2 1 TGS domain Hydrolase PF00702.26 CDJ67465.1 - 0.014 15.7 0.1 0.031 14.6 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase EnY2 PF10163.9 CDJ67466.1 - 1.1e-07 32.1 0.3 1.8e-07 31.4 0.3 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 Cofilin_ADF PF00241.20 CDJ67467.1 - 8.4e-27 93.4 0.0 1.1e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2842 PF11003.8 CDJ67468.1 - 0.055 13.7 1.7 0.086 13.1 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) Popeye PF04831.13 CDJ67468.1 - 0.15 12.3 4.0 0.2 11.9 4.0 1.2 1 0 0 1 1 1 0 Popeye protein conserved region Rtf2 PF04641.12 CDJ67469.1 - 3.5e-44 151.2 0.1 7.7e-44 150.0 0.1 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 CDJ67469.1 - 0.045 13.6 1.2 6.4 6.7 0.2 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Aconitase PF00330.20 CDJ67470.1 - 3.7e-184 613.0 0.0 4.9e-184 612.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDJ67470.1 - 4.5e-41 140.2 0.0 7.7e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-RING_11 PF17123.5 CDJ67471.1 - 1.9e-09 37.1 1.0 4.8e-09 35.8 1.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CDJ67471.1 - 2.2e-06 27.9 0.3 4.5e-06 26.9 0.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ67471.1 - 0.00038 20.4 0.1 0.00077 19.4 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ67471.1 - 0.0064 16.4 0.3 0.014 15.3 0.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain EI24 PF07264.11 CDJ67471.1 - 0.0088 16.3 0.8 0.011 16.0 0.8 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Prok-RING_1 PF14446.6 CDJ67471.1 - 0.04 13.8 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.6 CDJ67471.1 - 0.042 13.7 0.2 0.086 12.7 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ67471.1 - 0.12 12.2 0.4 0.25 11.3 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2207 PF09972.9 CDJ67471.1 - 0.43 9.3 0.8 0.51 9.1 0.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) STOP PF05217.12 CDJ67472.1 - 8e-06 26.0 4.9 0.0011 19.2 0.8 5.0 6 0 0 6 6 6 1 STOP protein PDEase_I PF00233.19 CDJ67473.1 - 1.8e-44 152.3 0.1 2.3e-44 151.9 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase EIAV_GP90 PF00971.18 CDJ67473.1 - 0.069 11.8 0.0 0.097 11.3 0.0 1.2 1 0 0 1 1 1 0 EIAV coat protein, gp90 Peptidase_U4 PF03419.13 CDJ67474.1 - 0.0055 16.0 1.7 0.0092 15.3 1.7 1.2 1 0 0 1 1 1 1 Sporulation factor SpoIIGA ADK PF00406.22 CDJ67476.1 - 1.1e-28 100.3 0.0 1.3e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDJ67476.1 - 1.6e-14 54.5 0.0 3.2e-14 53.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ67476.1 - 0.0001 22.9 0.0 0.00018 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ67476.1 - 0.0011 19.1 0.0 0.0018 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CDJ67476.1 - 0.0024 17.8 3.6 0.0057 16.6 3.6 1.7 1 1 0 1 1 1 1 Adenylate kinase, active site lid NACHT PF05729.12 CDJ67476.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 CDJ67476.1 - 0.015 15.7 0.3 0.11 12.9 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 CDJ67476.1 - 0.058 13.1 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase SKI PF01202.22 CDJ67476.1 - 0.063 13.4 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 Shikimate kinase Rad17 PF03215.15 CDJ67476.1 - 0.068 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Hydin_ADK PF17213.3 CDJ67476.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SET PF00856.28 CDJ67477.1 - 6.4e-08 33.2 0.1 1.4e-06 28.8 0.0 2.6 2 1 0 2 2 2 1 SET domain Coatomer_g_Cpla PF16381.5 CDJ67478.1 - 0.047 13.8 0.2 0.13 12.4 0.2 1.7 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform PPR_2 PF13041.6 CDJ67479.1 - 0.086 13.0 0.0 8 6.7 0.0 3.4 3 0 0 3 3 3 0 PPR repeat family ubiquitin PF00240.23 CDJ67481.1 - 0.0081 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF4131 PF13567.6 CDJ67481.1 - 0.098 12.3 2.1 0.2 11.3 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2407 PF10302.9 CDJ67481.1 - 0.21 12.2 0.0 0.3 11.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Coatomer_WDAD PF04053.14 CDJ67482.1 - 6.1e-05 22.3 1.8 0.0079 15.3 0.6 3.0 3 0 0 3 3 3 2 Coatomer WD associated region PD40 PF07676.12 CDJ67482.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat RMI1_N PF08585.12 CDJ67483.1 - 5e-16 59.1 1.3 8.2e-15 55.1 0.0 2.8 2 1 0 2 2 2 1 RecQ mediated genome instability protein M-factor PF03855.13 CDJ67483.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 M-factor Voldacs PF03517.13 CDJ67484.1 - 4.2e-25 88.5 0.0 6.8e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Lipase_3 PF01764.25 CDJ67485.1 - 3e-13 49.9 0.0 6.6e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Retrotrans_gag PF03732.17 CDJ67486.1 - 0.0038 17.5 0.0 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 CDJ67487.1 - 7.7e-13 48.1 0.0 1.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Hydin_ADK PF17213.3 CDJ67488.1 - 0.075 13.3 14.9 0.092 13.0 14.9 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Zip PF02535.22 CDJ67488.1 - 0.82 8.8 3.6 1 8.5 3.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF572 PF04502.13 CDJ67488.1 - 1.4 8.5 20.3 1.8 8.1 20.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3474 PF11960.8 CDJ67488.1 - 2.6 8.2 6.3 4.5 7.5 6.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) VIT1 PF01988.19 CDJ67488.1 - 4.1 7.2 7.9 5.1 6.9 7.9 1.2 1 0 0 1 1 1 0 VIT family AUX_IAA PF02309.16 CDJ67488.1 - 6.5 6.5 13.2 9.5 6.0 13.2 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF4551 PF15087.6 CDJ67488.1 - 7.1 5.3 16.2 8.1 5.1 16.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Spt20 PF12090.8 CDJ67489.1 - 0.00082 19.0 13.0 0.00082 19.0 13.0 3.7 4 1 0 4 4 4 1 Spt20 family CLN3 PF02487.17 CDJ67489.1 - 0.0012 18.0 1.0 0.0012 18.0 1.0 2.2 2 1 0 2 2 2 1 CLN3 protein DUF2722 PF10846.8 CDJ67489.1 - 0.0014 17.7 10.6 0.0014 17.7 10.6 4.3 4 1 0 4 4 4 1 Protein of unknown function (DUF2722) DUF3810 PF12725.7 CDJ67489.1 - 0.026 13.9 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Sulf_transp PF04143.14 CDJ67489.1 - 0.027 14.1 0.1 0.027 14.1 0.1 1.8 2 0 0 2 2 2 0 Sulphur transport G0-G1_switch_2 PF15103.6 CDJ67489.1 - 0.028 14.8 8.2 0.14 12.6 0.6 3.5 3 0 0 3 3 3 0 G0/G1 switch protein 2 DUF3381 PF11861.8 CDJ67489.1 - 0.59 9.9 13.6 0.52 10.1 9.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) V_ATPase_I PF01496.19 CDJ67489.1 - 2.2 6.1 10.5 0.16 9.9 5.2 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 CDJ67489.1 - 2.6 7.3 24.4 0.75 9.1 16.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GcpE PF04551.14 CDJ67490.1 - 9.5e-134 445.9 0.3 2.8e-133 444.4 0.3 1.6 1 1 0 1 1 1 1 GcpE protein LRR_4 PF12799.7 CDJ67491.1 - 2.3e-05 24.7 0.5 2.3e-05 24.7 0.5 2.7 1 1 2 3 3 3 1 Leucine Rich repeats (2 copies) DUF1645 PF07816.11 CDJ67491.1 - 0.00038 21.1 4.0 0.0005 20.7 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) LRR_8 PF13855.6 CDJ67491.1 - 0.0015 18.3 0.5 0.0015 18.3 0.5 1.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 CDJ67491.1 - 0.26 10.8 0.7 0.33 10.4 0.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeat SR-25 PF10500.9 CDJ67491.1 - 3.7 7.1 19.9 5.4 6.6 19.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ67493.1 - 0.0008 19.5 21.5 0.00087 19.4 21.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Tau95_N PF17682.1 CDJ67493.1 - 0.12 12.6 2.7 0.16 12.1 2.7 1.1 1 0 0 1 1 1 0 Tau95 Triple barrel domain HA2 PF04408.23 CDJ67493.1 - 0.75 10.1 6.1 1 9.7 6.1 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) Activator_LAG-3 PF11498.8 CDJ67493.1 - 1.4 7.8 37.5 2 7.3 37.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Presenilin PF01080.17 CDJ67493.1 - 2.6 6.7 9.3 3 6.5 9.3 1.1 1 0 0 1 1 1 0 Presenilin HA2 PF04408.23 CDJ67494.1 - 1.1e-18 67.5 0.2 1.1e-18 67.5 0.2 3.4 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDJ67494.1 - 1.3e-08 35.2 0.3 1.4e-06 28.6 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF2722 PF10846.8 CDJ67494.1 - 0.00017 20.7 21.9 0.00023 20.3 6.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) DDHD PF02862.17 CDJ67494.1 - 0.49 10.5 6.0 0.45 10.6 0.3 2.2 2 0 0 2 2 2 0 DDHD domain PDDEXK_6 PF04720.12 CDJ67494.1 - 0.59 10.0 8.8 0.29 11.1 0.3 2.2 2 0 0 2 2 2 0 PDDEXK-like family of unknown function ADP_PFK_GK PF04587.15 CDJ67494.1 - 0.69 8.4 3.7 1.1 7.8 3.7 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region DUF4834 PF16118.5 CDJ67495.1 - 0.087 13.8 3.6 4.2 8.4 0.2 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 CDJ67495.1 - 0.3 12.0 8.9 2.7 8.9 0.2 4.0 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain SfLAP PF11139.8 CDJ67495.1 - 3.5 7.0 17.8 2.6 7.4 0.3 3.3 4 0 0 4 4 4 0 Sap, sulfolipid-1-addressing protein MRC1 PF09444.10 CDJ67495.1 - 8.6 6.9 7.5 22 5.5 1.3 2.1 2 0 0 2 2 2 0 MRC1-like domain VHS PF00790.19 CDJ67496.1 - 0.00027 20.8 0.2 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 VHS domain kleA_kleC PF17383.2 CDJ67496.1 - 0.052 13.9 0.1 0.096 13.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A TAF4 PF05236.14 CDJ67497.1 - 0.0015 18.3 15.9 0.0015 18.3 15.9 2.1 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family SUIM_assoc PF16619.5 CDJ67497.1 - 0.02 15.0 4.8 0.02 15.0 4.8 6.4 2 1 2 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 RFamide_26RFa PF11109.8 CDJ67497.1 - 0.075 13.5 0.6 0.075 13.5 0.6 3.1 2 1 1 3 3 3 0 Orexigenic neuropeptide Qrfp/P518 Presenilin PF01080.17 CDJ67498.1 - 0.0037 16.1 30.2 0.0037 16.1 30.2 7.6 4 2 0 4 4 4 1 Presenilin RskA PF10099.9 CDJ67499.1 - 0.003 17.9 8.7 0.003 17.9 8.7 12.8 4 3 2 10 10 10 3 Anti-sigma-K factor rskA Vps53_N PF04100.12 CDJ67500.1 - 8.2e-43 146.8 3.0 7.7e-26 90.9 1.3 2.6 3 0 0 3 3 3 2 Vps53-like, N-terminal SPX PF03105.19 CDJ67500.1 - 0.00013 22.0 32.9 0.001 19.0 12.4 3.5 4 0 0 4 4 4 2 SPX domain TFIIA PF03153.13 CDJ67500.1 - 0.0012 18.9 17.9 0.0012 18.9 17.9 4.3 2 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ67500.1 - 1.5 7.0 44.5 0.18 10.0 7.9 3.2 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 Tyrosinase PF00264.20 CDJ67500.1 - 8.4 6.6 14.3 0.24 11.7 3.4 2.7 3 0 0 3 3 3 0 Common central domain of tyrosinase Cyt-b5 PF00173.28 CDJ67501.1 - 0.18 11.9 0.0 0.79 9.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain Archease PF01951.16 CDJ67502.1 - 2.8e-19 69.7 16.6 5e-11 43.0 0.3 2.8 2 1 1 3 3 2 2 Archease protein family (MTH1598/TM1083) SARAF PF06682.12 CDJ67502.1 - 0.0013 18.5 13.4 0.01 15.5 4.1 2.1 2 0 0 2 2 2 2 SOCE-associated regulatory factor of calcium homoeostasis PHD_4 PF16866.5 CDJ67502.1 - 0.026 14.6 2.5 0.026 14.6 2.5 2.2 2 0 0 2 2 2 0 PHD-finger RAP1 PF07218.11 CDJ67502.1 - 0.043 12.1 14.7 0.057 11.7 14.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2489 PF10675.9 CDJ67502.1 - 0.089 12.7 20.1 0.15 12.0 2.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2489) Lin-8 PF03353.15 CDJ67502.1 - 0.25 10.9 15.7 0.68 9.4 7.9 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Rpp20 PF12328.8 CDJ67502.1 - 0.39 10.7 8.6 19 5.2 1.8 3.3 3 0 0 3 3 3 0 Rpp20 subunit of nuclear RNase MRP and P DUF508 PF04370.12 CDJ67502.1 - 0.5 10.1 9.5 1.8 8.3 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Nse4_C PF08743.10 CDJ67502.1 - 0.64 10.3 7.1 5.1 7.4 0.2 2.7 2 0 0 2 2 2 0 Nse4 C-terminal Mss4 PF04421.13 CDJ67502.1 - 1.2 9.3 4.0 2.8 8.1 0.5 2.3 2 0 0 2 2 2 0 Mss4 protein Secretin_N_2 PF07655.13 CDJ67502.1 - 2.3 8.8 18.3 0.72 10.4 12.3 2.7 3 0 0 3 3 3 0 Secretin N-terminal domain Vps39_1 PF10366.9 CDJ67502.1 - 3.9 7.8 9.1 1.7 9.0 3.2 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 EphA2_TM PF14575.6 CDJ67502.1 - 6 7.8 8.1 31 5.5 0.6 3.3 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain RskA PF10099.9 CDJ67503.1 - 0.0069 16.7 91.1 0.023 15.0 0.0 4.7 1 1 2 3 3 1 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ67503.1 - 0.0074 15.9 67.0 0.036 13.7 38.9 2.3 2 0 0 2 2 2 2 Spt20 family Zip PF02535.22 CDJ67503.1 - 0.03 13.5 6.5 0.91 8.7 1.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 CDJ67503.1 - 0.037 12.4 6.1 0.18 10.2 1.1 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 EPL1 PF10513.9 CDJ67503.1 - 0.041 14.3 22.3 0.06 13.7 8.3 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Band_3_cyto PF07565.13 CDJ67503.1 - 0.087 12.6 17.6 0.015 15.1 4.2 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PA26 PF04636.13 CDJ67503.1 - 0.087 11.7 14.1 0.4 9.6 2.8 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) EOS1 PF12326.8 CDJ67503.1 - 0.19 11.6 8.6 0.22 11.5 1.7 2.3 2 0 0 2 2 2 0 N-glycosylation protein Serinc PF03348.15 CDJ67503.1 - 0.26 10.2 11.5 1.4 7.8 3.6 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) UPF0560 PF10577.9 CDJ67503.1 - 0.34 9.4 28.3 0.75 8.2 16.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 SpoIIP PF07454.11 CDJ67503.1 - 0.35 10.3 25.5 0.041 13.3 10.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CLN3 PF02487.17 CDJ67503.1 - 0.4 9.7 15.7 1.5 7.7 7.5 2.2 2 0 0 2 2 2 0 CLN3 protein FAM60A PF15396.6 CDJ67503.1 - 0.57 10.2 19.0 0.37 10.8 5.4 2.5 2 0 0 2 2 2 0 Protein Family FAM60A Gti1_Pac2 PF09729.9 CDJ67503.1 - 0.62 10.1 19.5 0.048 13.8 3.4 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family Neur_chan_memb PF02932.16 CDJ67503.1 - 0.95 9.5 23.8 0.35 10.9 6.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MDM10 PF12519.8 CDJ67503.1 - 1.1 8.0 15.3 0.99 8.2 6.4 2.1 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 TERB2 PF15101.6 CDJ67503.1 - 1.4 9.0 34.3 0.11 12.5 16.6 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF913 PF06025.12 CDJ67503.1 - 1.5 7.7 16.8 0.35 9.8 4.7 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF4820 PF16091.5 CDJ67503.1 - 1.5 8.1 18.6 0.22 10.9 5.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RR_TM4-6 PF06459.12 CDJ67503.1 - 1.8 8.3 28.8 0.075 12.9 7.8 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 VIR_N PF15912.5 CDJ67503.1 - 1.9 8.0 14.7 0.82 9.2 2.1 2.5 2 0 0 2 2 2 0 Virilizer, N-terminal CDC45 PF02724.14 CDJ67503.1 - 2.2 6.5 18.4 0.093 11.0 4.5 2.1 2 0 0 2 2 2 0 CDC45-like protein NPR3 PF03666.13 CDJ67503.1 - 2.2 7.0 25.2 1.2 7.8 6.6 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 eIF-3_zeta PF05091.12 CDJ67503.1 - 2.4 7.0 31.0 0.093 11.7 13.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF5523 PF17661.1 CDJ67503.1 - 2.6 7.7 23.9 0.41 10.3 9.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) SLC12 PF03522.15 CDJ67503.1 - 3.3 6.6 23.5 0.19 10.7 7.8 2.1 2 0 0 2 2 2 0 Solute carrier family 12 MCU PF04678.13 CDJ67503.1 - 3.3 7.8 14.3 2.3 8.3 7.2 2.5 2 0 0 2 2 2 0 Mitochondrial calcium uniporter RLL PF10036.9 CDJ67503.1 - 3.4 7.4 31.2 0.51 10.1 16.1 2.4 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein MAT1 PF06391.13 CDJ67503.1 - 4.5 7.0 26.8 1.1 9.1 14.0 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Lin-8 PF03353.15 CDJ67503.1 - 4.9 6.6 31.5 0.38 10.3 13.8 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Activator_LAG-3 PF11498.8 CDJ67503.1 - 6.1 5.7 64.1 0.67 8.9 10.9 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Afi1 PF07792.12 CDJ67503.1 - 6.3 7.3 20.6 0.58 10.6 7.3 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MecA PF05389.12 CDJ67503.1 - 9.4 5.8 16.8 0.22 11.2 4.8 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Tic110 PF16940.5 CDJ67505.1 - 1.1 7.7 17.7 1.2 7.6 17.7 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter SR-25 PF10500.9 CDJ67505.1 - 3 7.4 19.1 4.2 6.9 13.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IHABP4_N PF16174.5 CDJ67505.1 - 3.9 8.1 5.9 8 7.0 5.9 1.6 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal PIP5K PF01504.18 CDJ67506.1 - 0.043 13.0 9.3 0.29 10.3 5.0 2.5 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Zip PF02535.22 CDJ67506.1 - 0.2 10.8 6.9 0.61 9.3 6.9 1.8 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 CDJ67506.1 - 0.45 8.9 0.9 0.99 7.7 0.9 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SUIM_assoc PF16619.5 CDJ67506.1 - 1.2 9.2 0.0 1.2 9.2 0.0 6.3 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF4746 PF15928.5 CDJ67506.1 - 3.7 6.9 12.9 5 6.5 9.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF808 PF05661.12 CDJ67506.1 - 4 6.4 11.9 0.51 9.3 0.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF808) DUF3492 PF11997.8 CDJ67506.1 - 4.5 6.9 8.4 4.3 7.0 5.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) PGA2 PF07543.12 CDJ67507.1 - 0.15 12.0 8.0 0.15 12.0 8.0 1.0 1 0 0 1 1 1 0 Protein trafficking PGA2 Spt20 PF12090.8 CDJ67507.1 - 2.3 7.8 31.4 2.2 7.8 31.4 1.0 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ67507.1 - 6.5 7.8 14.5 6.1 7.9 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DivIC PF04977.15 CDJ67507.1 - 10 6.0 17.1 10 6.0 17.1 1.1 1 0 0 1 1 1 0 Septum formation initiator eIF_4EBP PF05456.11 CDJ67508.1 - 0.0069 16.3 3.7 0.0084 16.0 3.7 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Lipase_GDSL_3 PF14606.6 CDJ67508.1 - 0.023 14.8 0.5 0.028 14.6 0.5 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family OmpH PF03938.14 CDJ67508.1 - 0.059 13.7 20.7 0.06 13.7 20.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2722 PF10846.8 CDJ67508.1 - 0.22 10.4 16.9 0.21 10.5 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Exonuc_VII_L PF02601.15 CDJ67508.1 - 0.29 10.6 10.6 0.29 10.7 10.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 CDJ67508.1 - 0.33 10.3 8.3 0.32 10.3 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCU PF04678.13 CDJ67508.1 - 0.43 10.7 4.6 0.47 10.5 4.6 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter TFIIA PF03153.13 CDJ67508.1 - 0.49 10.3 24.3 0.47 10.4 24.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FadA PF09403.10 CDJ67508.1 - 0.58 10.7 17.8 0.86 10.1 17.8 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Spt20 PF12090.8 CDJ67508.1 - 0.65 9.6 28.1 0.69 9.5 28.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF2968 PF11180.8 CDJ67508.1 - 1.1 8.8 25.9 1.3 8.6 25.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4834 PF16118.5 CDJ67508.1 - 1.5 9.9 6.6 1.8 9.6 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ67508.1 - 3.6 6.2 5.9 3.6 6.2 5.9 1.0 1 0 0 1 1 1 0 Presenilin MctB PF11382.8 CDJ67508.1 - 3.7 7.2 11.9 4.9 6.8 11.9 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB TERB2 PF15101.6 CDJ67508.1 - 4.4 7.3 11.0 4.7 7.2 11.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DivIC PF04977.15 CDJ67508.1 - 4.8 7.0 18.3 8.1 6.3 18.3 1.4 1 0 0 1 1 1 0 Septum formation initiator Androgen_recep PF02166.16 CDJ67508.1 - 6.3 5.5 25.1 6 5.6 25.1 1.1 1 0 0 1 1 1 0 Androgen receptor zf-CCHC PF00098.23 CDJ67509.1 - 1.3e-05 25.1 10.9 0.0021 18.1 1.2 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ67509.1 - 0.01 15.8 2.6 0.046 13.7 0.0 2.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ67509.1 - 0.048 13.5 6.5 0.11 12.3 0.1 2.6 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 CDJ67509.1 - 0.092 13.0 0.0 0.49 10.7 0.0 2.1 3 0 0 3 3 3 0 Retrotransposon gag protein DUF3425 PF11905.8 CDJ67509.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) DnaJ_CXXCXGXG PF00684.19 CDJ67509.1 - 0.25 11.7 6.5 1.4 9.3 6.7 1.9 1 1 1 2 2 2 0 DnaJ central domain zf-CCHC_4 PF14392.6 CDJ67509.1 - 0.54 10.0 3.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Zinc knuckle Zn_Tnp_IS1595 PF12760.7 CDJ67509.1 - 6.8 6.7 7.3 30 4.7 6.9 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain rve PF00665.26 CDJ67510.1 - 4.5e-15 55.9 0.0 6.7e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ67510.1 - 0.0038 17.0 0.1 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DUF5427 PF10310.9 CDJ67511.1 - 2.6 6.9 6.1 2.9 6.7 6.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SF-assemblin PF06705.11 CDJ67513.1 - 3e-42 144.7 14.4 3.4e-42 144.5 14.4 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin PIN_8 PF18476.1 CDJ67513.1 - 0.022 14.6 7.8 0.028 14.3 7.8 1.2 1 0 0 1 1 1 0 PIN like domain DUF4238 PF14022.6 CDJ67513.1 - 0.44 10.0 4.9 0.52 9.8 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Exonuc_VII_L PF02601.15 CDJ67513.1 - 1 8.8 9.0 1.4 8.5 9.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF641 PF04859.12 CDJ67513.1 - 2.2 8.7 11.8 11 6.3 11.2 2.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) AAA_11 PF13086.6 CDJ67513.1 - 2.7 7.7 7.5 3.4 7.4 7.5 1.1 1 0 0 1 1 1 0 AAA domain Metal_resist PF13801.6 CDJ67514.1 - 0.0014 18.8 5.3 0.0064 16.7 5.3 1.9 1 1 0 1 1 1 1 Heavy-metal resistance Spt20 PF12090.8 CDJ67514.1 - 0.02 14.5 18.0 0.025 14.2 18.0 1.1 1 0 0 1 1 1 0 Spt20 family UPF0242 PF06785.11 CDJ67514.1 - 0.17 12.0 15.4 0.19 11.8 15.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Borrelia_P83 PF05262.11 CDJ67514.1 - 3 6.2 12.7 3 6.2 12.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 CDJ67514.1 - 3 6.5 5.7 3.2 6.4 5.7 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ67514.1 - 3.4 7.5 20.0 3.7 7.4 20.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ER PF01133.17 CDJ67515.1 - 7.5e-28 96.4 0.0 1.2e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Enhancer of rudimentary Spt20 PF12090.8 CDJ67515.1 - 0.0055 16.4 1.5 0.0064 16.1 1.5 1.2 1 0 0 1 1 1 1 Spt20 family Macoilin PF09726.9 CDJ67515.1 - 0.019 13.6 0.2 0.019 13.6 0.2 2.3 2 1 1 3 3 3 0 Macoilin family Tryp_alpha_amyl PF00234.22 CDJ67515.1 - 0.049 14.1 7.9 4.3 7.8 4.5 2.4 2 0 0 2 2 2 0 Protease inhibitor/seed storage/LTP family Activator_LAG-3 PF11498.8 CDJ67515.1 - 1.5 7.7 19.8 5.7 5.8 0.0 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SNF2_N PF00176.23 CDJ67516.1 - 6e-11 41.7 0.5 1.8e-05 23.7 0.0 3.3 3 0 0 3 3 3 3 SNF2 family N-terminal domain SMC_N PF02463.19 CDJ67519.1 - 2.9e-09 36.7 0.7 3.3e-09 36.5 0.7 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ67519.1 - 3.1e-08 34.4 10.1 3.7e-07 30.8 9.9 2.0 1 1 0 1 1 1 1 AAA domain Chorion_2 PF03964.15 CDJ67519.1 - 0.003 18.3 5.7 0.0049 17.7 5.7 1.4 1 0 0 1 1 1 1 Chorion family 2 SR-25 PF10500.9 CDJ67519.1 - 0.0065 16.1 11.3 0.0093 15.6 11.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ67519.1 - 0.01 15.4 7.9 0.012 15.2 7.9 1.1 1 0 0 1 1 1 0 Spt20 family AAA_29 PF13555.6 CDJ67519.1 - 0.013 15.2 0.1 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TFIIA PF03153.13 CDJ67519.1 - 0.013 15.5 5.3 0.014 15.5 5.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PH_5 PF15405.6 CDJ67519.1 - 0.016 15.3 0.9 0.023 14.8 0.9 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain DUF789 PF05623.12 CDJ67519.1 - 0.019 14.7 2.5 0.025 14.3 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) DUF2722 PF10846.8 CDJ67519.1 - 0.024 13.6 8.8 0.028 13.4 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Aminotran_1_2 PF00155.21 CDJ67519.1 - 0.048 12.8 2.1 0.06 12.5 2.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II AAA_15 PF13175.6 CDJ67519.1 - 0.055 13.2 1.2 0.081 12.6 0.1 1.5 1 1 1 2 2 2 0 AAA ATPase domain DUF3446 PF11928.8 CDJ67519.1 - 0.061 13.6 10.4 0.097 13.0 10.4 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain Pox_A12 PF04651.13 CDJ67519.1 - 0.076 13.1 1.5 0.085 12.9 1.5 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein Pex14_N PF04695.13 CDJ67519.1 - 0.078 13.6 7.1 0.11 13.2 7.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med3 PF11593.8 CDJ67519.1 - 0.081 12.1 7.7 0.1 11.8 7.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal IMUP PF15761.5 CDJ67519.1 - 0.12 13.1 10.7 0.22 12.2 10.7 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein CDK2AP PF09806.9 CDJ67519.1 - 0.42 10.6 9.8 0.59 10.2 9.8 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4834 PF16118.5 CDJ67519.1 - 0.48 11.4 2.3 0.82 10.7 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Coilin_N PF15862.5 CDJ67519.1 - 1 9.1 5.5 1.6 8.5 5.5 1.2 1 0 0 1 1 1 0 Coilin N-terminus PSRT PF07636.11 CDJ67520.1 - 0.035 13.8 3.7 0.062 13.0 3.7 1.4 1 0 0 1 1 1 0 PSRT DUF4366 PF14283.6 CDJ67520.1 - 0.45 10.6 4.1 0.5 10.4 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2076 PF09849.9 CDJ67520.1 - 0.53 10.3 19.2 0.63 10.0 19.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CDK2AP PF09806.9 CDJ67520.1 - 0.95 9.5 16.7 1.1 9.3 16.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Spt20 PF12090.8 CDJ67520.1 - 1.2 8.7 14.8 1.2 8.7 14.8 1.1 1 0 0 1 1 1 0 Spt20 family Mif2_N PF15624.6 CDJ67520.1 - 1.5 9.6 6.5 1.7 9.3 6.5 1.1 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Pex14_N PF04695.13 CDJ67520.1 - 1.5 9.5 12.4 2 9.0 12.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CtnDOT_TraJ PF07863.11 CDJ67520.1 - 3.2 8.5 6.5 11 6.7 1.0 2.2 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon Senescence_reg PF04520.13 CDJ67520.1 - 3.9 8.3 11.9 4.3 8.2 11.9 1.1 1 0 0 1 1 1 0 Senescence regulator TFIIA PF03153.13 CDJ67520.1 - 5.9 6.8 16.7 7 6.5 16.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ67520.1 - 9 5.8 7.5 8.6 5.8 7.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIF_alpha PF05793.12 CDJ67522.1 - 0.016 13.8 4.2 0.017 13.7 4.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SARAF PF06682.12 CDJ67522.1 - 2.8 7.5 18.4 3.9 7.0 18.4 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Integrase_H2C2 PF17921.1 CDJ67523.1 - 3.4e-16 59.1 0.3 1.2e-15 57.4 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CDJ67523.1 - 6.7e-16 58.5 0.3 1.4e-15 57.5 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ67523.1 - 1.1e-14 54.7 0.1 5.5e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 CDJ67523.1 - 9.8e-06 25.5 0.0 2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CDJ67523.1 - 0.0021 18.2 0.2 0.0054 16.9 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_3 PF13456.6 CDJ67523.1 - 0.041 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like rve_3 PF13683.6 CDJ67523.1 - 0.078 12.8 0.1 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 Integrase core domain Mvb12 PF09452.10 CDJ67523.1 - 0.086 13.3 0.0 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Chorion_2 PF03964.15 CDJ67524.1 - 0.027 15.3 4.0 0.027 15.3 4.0 3.8 3 1 0 3 3 3 0 Chorion family 2 ETRAMP PF09716.10 CDJ67524.1 - 2.5 8.2 0.0 2.5 8.2 0.0 2.5 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) CBM_20 PF00686.19 CDJ67525.1 - 6.5e-17 61.2 0.0 1e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Starch binding domain Peptidase_C8 PF03569.13 CDJ67525.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C8 RAP1 PF07218.11 CDJ67525.1 - 5.8 5.1 7.6 7.9 4.6 7.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Collagen PF01391.18 CDJ67526.1 - 0.00087 19.0 19.9 0.00087 19.0 19.9 13.3 11 3 1 12 12 12 2 Collagen triple helix repeat (20 copies) Eapp_C PF10238.9 CDJ67528.1 - 3.7 7.6 21.3 6.5 6.8 1.9 3.6 3 0 0 3 3 3 0 E2F-associated phosphoprotein DUF4148 PF13663.6 CDJ67529.1 - 0.012 15.8 1.8 0.012 15.8 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF3995 PF13160.6 CDJ67529.1 - 0.025 14.9 6.3 0.67 10.3 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) DUF3824 PF12868.7 CDJ67529.1 - 0.029 15.0 11.9 0.029 15.0 11.9 2.0 1 1 1 2 2 1 0 Domain of unknwon function (DUF3824) Pex14_N PF04695.13 CDJ67529.1 - 0.069 13.8 17.3 0.076 13.7 17.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3180 PF11377.8 CDJ67529.1 - 0.079 13.1 15.3 2.8 8.1 15.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3180) RAB3GAP2_N PF14655.6 CDJ67529.1 - 0.2 10.9 3.6 0.25 10.6 3.6 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ribosomal_60s PF00428.19 CDJ67529.1 - 0.2 12.2 23.5 0.31 11.7 4.8 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ67529.1 - 0.66 9.9 22.6 0.76 9.7 22.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ67529.1 - 1.1 8.8 16.5 1.1 8.8 16.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF4366 PF14283.6 CDJ67529.1 - 1.5 8.8 4.0 2.1 8.4 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RskA PF10099.9 CDJ67529.1 - 3 8.1 35.7 1.6 9.0 13.1 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA CPSF100_C PF13299.6 CDJ67529.1 - 3.3 7.9 6.2 3.7 7.7 6.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4834 PF16118.5 CDJ67529.1 - 3.3 8.7 5.0 4.3 8.4 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 CDJ67529.1 - 3.7 7.5 5.1 4 7.4 5.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Robl_LC7 PF03259.17 CDJ67529.1 - 6.3 6.6 12.1 3.4 7.5 1.9 2.1 2 0 0 2 2 2 0 Roadblock/LC7 domain Presenilin PF01080.17 CDJ67529.1 - 7.6 5.2 8.4 8.3 5.1 8.4 1.0 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ67529.1 - 9.6 4.3 16.2 10 4.2 16.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Phage_H_T_join PF05521.11 CDJ67530.1 - 0.045 14.3 2.1 0.056 13.9 2.1 1.2 1 0 0 1 1 1 0 Phage head-tail joining protein Dsh_C PF12316.8 CDJ67530.1 - 3.9 7.8 20.1 4 7.8 20.1 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Hamartin PF04388.12 CDJ67530.1 - 7.1 5.2 15.9 7.5 5.1 15.9 1.0 1 0 0 1 1 1 0 Hamartin protein CCSAP PF15748.5 CDJ67530.1 - 7.7 6.6 18.4 8.7 6.4 18.4 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PIP5K PF01504.18 CDJ67531.1 - 1.3e-28 100.0 13.4 3.2e-21 75.8 0.1 3.0 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase PT PF04886.12 CDJ67531.1 - 0.0074 15.8 10.0 0.017 14.6 5.6 4.0 3 1 1 4 4 4 2 PT repeat Spt20 PF12090.8 CDJ67531.1 - 0.16 11.6 15.2 0.25 10.9 15.2 1.3 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 CDJ67531.1 - 0.26 10.2 5.9 0.34 9.8 5.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RVP_2 PF08284.11 CDJ67532.1 - 6.3e-12 45.4 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ67532.1 - 3e-08 34.2 0.0 1.2e-07 32.3 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ67532.1 - 6.1e-08 33.1 0.0 1.6e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 CDJ67532.1 - 0.00077 19.0 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 CDJ67532.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease D-ser_dehydrat PF14031.6 CDJ67532.1 - 0.14 12.9 0.0 0.38 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative serine dehydratase domain His_Phos_1 PF00300.22 CDJ67533.1 - 7.5e-10 38.8 2.1 7.3e-08 32.3 0.1 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF1635 PF07795.11 CDJ67533.1 - 0.0097 15.8 5.7 0.015 15.2 5.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) GREB1 PF15782.5 CDJ67533.1 - 0.031 11.4 0.9 0.031 11.4 0.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SR-25 PF10500.9 CDJ67533.1 - 0.057 13.0 10.2 0.076 12.6 10.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Kei1 PF08552.11 CDJ67533.1 - 0.09 12.6 0.5 0.13 12.1 0.5 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DNA_pol3_a_NII PF11490.8 CDJ67533.1 - 0.2 11.5 3.6 0.31 10.9 3.6 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II DUF1180 PF06679.12 CDJ67533.1 - 0.23 11.9 4.4 0.68 10.3 4.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Roughex PF06020.11 CDJ67533.1 - 0.26 10.4 3.5 0.32 10.0 3.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein AF-4 PF05110.13 CDJ67533.1 - 0.28 9.2 10.5 0.32 9.0 10.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Androgen_recep PF02166.16 CDJ67533.1 - 2 7.1 13.2 0.034 13.0 5.4 1.8 2 0 0 2 2 2 0 Androgen receptor Spt20 PF12090.8 CDJ67533.1 - 9.9 5.7 17.3 15 5.2 17.3 1.3 1 1 0 1 1 1 0 Spt20 family zf-CCHC PF00098.23 CDJ67534.1 - 0.00093 19.2 0.8 0.00093 19.2 0.8 1.8 2 0 0 2 2 2 1 Zinc knuckle Cofac_haem_bdg PF04187.13 CDJ67534.1 - 0.04 13.9 0.3 0.078 13.0 0.1 1.7 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN RT_RNaseH_2 PF17919.1 CDJ67535.1 - 4.4e-29 100.4 0.1 8.2e-29 99.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ67535.1 - 1.7e-28 99.0 0.1 3.4e-28 98.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ67535.1 - 3e-21 76.0 0.0 5.5e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ67535.1 - 1.8e-17 63.2 1.0 3.4e-17 62.3 1.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ67535.1 - 4.7e-10 39.7 0.0 1.3e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ67535.1 - 0.00044 20.4 0.3 0.00086 19.5 0.3 1.5 1 0 0 1 1 1 1 H2C2 zinc finger ATP-synt_ab PF00006.25 CDJ67536.1 - 3.7e-67 226.1 0.1 4.4e-67 225.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Spherulin4 PF12138.8 CDJ67536.1 - 0.054 13.1 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Spherulation-specific family 4 Amidohydro_1 PF01979.20 CDJ67536.1 - 0.14 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family Menin PF05053.13 CDJ67537.1 - 0.0044 15.4 7.2 0.006 15.0 7.2 1.2 1 0 0 1 1 1 1 Menin RAB3GAP2_N PF14655.6 CDJ67537.1 - 0.046 13.0 3.0 0.064 12.5 3.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TraT PF05818.12 CDJ67537.1 - 0.31 10.7 7.2 0.16 11.7 5.3 1.4 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein Dehydrin PF00257.19 CDJ67537.1 - 0.32 11.5 7.3 0.05 14.2 3.6 1.5 2 0 0 2 2 2 0 Dehydrin RIFIN PF02009.16 CDJ67537.1 - 0.36 10.7 3.2 0.56 10.1 3.2 1.3 1 0 0 1 1 1 0 Rifin DUF3597 PF12200.8 CDJ67537.1 - 3.3 8.3 17.3 1.3 9.5 8.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) SR-25 PF10500.9 CDJ67538.1 - 0.0023 17.6 14.4 0.0023 17.6 14.4 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Med24_N PF11277.8 CDJ67538.1 - 0.15 10.1 0.7 0.17 9.9 0.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Plasmodium_Vir PF05795.11 CDJ67538.1 - 0.44 9.9 2.1 0.64 9.4 2.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MPM1 PF17234.2 CDJ67538.1 - 2.3 8.4 6.4 0.31 11.3 2.6 1.4 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Peptidase_S49_N PF08496.10 CDJ67539.1 - 0.096 12.7 0.3 0.096 12.7 0.3 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal G0-G1_switch_2 PF15103.6 CDJ67539.1 - 3.1 8.3 10.7 0.92 10.0 3.0 2.5 2 0 0 2 2 2 0 G0/G1 switch protein 2 SLC12 PF03522.15 CDJ67539.1 - 3.9 6.4 11.4 5.2 6.0 11.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Spt20 PF12090.8 CDJ67539.1 - 6.3 6.3 37.5 1.9 8.0 17.2 2.2 2 0 0 2 2 2 0 Spt20 family HA2 PF04408.23 CDJ67539.1 - 6.4 7.1 9.4 0.11 12.8 1.8 2.0 2 1 0 2 2 2 0 Helicase associated domain (HA2) Fasciclin PF02469.22 CDJ67540.1 - 5.6e-10 39.5 1.8 0.00017 21.8 0.0 3.7 2 1 0 2 2 2 2 Fasciclin domain TFIIA PF03153.13 CDJ67540.1 - 3.3e-07 30.7 62.3 0.00086 19.4 28.3 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Otopetrin PF03189.13 CDJ67540.1 - 0.0016 17.4 0.0 0.0028 16.6 0.0 1.3 1 1 0 1 1 1 1 Otopetrin EIF4E-T PF10477.9 CDJ67540.1 - 0.0024 16.8 6.3 0.0024 16.8 6.3 2.3 2 0 0 2 2 2 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Suf PF05843.14 CDJ67540.1 - 0.0041 17.1 4.5 0.0041 17.1 4.5 2.8 2 1 0 2 2 1 1 Suppressor of forked protein (Suf) THOC2_N PF16134.5 CDJ67540.1 - 0.0075 15.0 2.4 0.0075 15.0 2.4 2.5 2 1 0 2 2 1 1 THO complex subunit 2 N-terminus Velvet PF11754.8 CDJ67540.1 - 0.015 15.2 18.5 0.019 14.9 1.3 2.3 2 0 0 2 2 2 0 Velvet factor PNISR PF15996.5 CDJ67540.1 - 0.016 15.5 22.0 0.052 13.8 8.1 2.5 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR MecA PF05389.12 CDJ67540.1 - 0.03 13.9 0.4 0.03 13.9 0.4 3.0 2 1 0 2 2 1 0 Negative regulator of genetic competence (MecA) Spore_YhcN_YlaJ PF09580.10 CDJ67540.1 - 0.052 13.6 13.0 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FAM60A PF15396.6 CDJ67540.1 - 0.13 12.3 13.8 0.54 10.2 3.9 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF4551 PF15087.6 CDJ67540.1 - 0.16 10.7 14.2 0.29 9.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) DUF572 PF04502.13 CDJ67540.1 - 0.23 11.0 16.6 0.45 10.1 2.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Presenilin PF01080.17 CDJ67540.1 - 0.35 9.6 26.3 0.057 12.2 0.8 2.1 2 0 0 2 2 2 0 Presenilin DUF4746 PF15928.5 CDJ67540.1 - 0.56 9.6 13.3 0.32 10.4 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) BORG_CEP PF14957.6 CDJ67540.1 - 0.69 11.1 15.9 3.4 8.8 4.9 2.6 2 0 0 2 2 2 0 Cdc42 effector EFTUD2 PF16004.5 CDJ67540.1 - 1.2 9.7 20.8 0.39 11.3 1.0 2.4 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus SARAF PF06682.12 CDJ67540.1 - 2.3 7.8 31.5 0.44 10.1 7.2 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SpoIIP PF07454.11 CDJ67540.1 - 3.4 7.0 24.0 0.23 10.9 3.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) LAP1C PF05609.12 CDJ67540.1 - 4.1 6.4 24.1 2.3 7.2 2.6 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Pex14_N PF04695.13 CDJ67540.1 - 5 7.8 60.7 0.19 12.3 26.8 3.1 3 1 0 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase_fungal PF17667.1 CDJ67540.1 - 5.3 5.7 8.6 6.7 5.4 2.4 2.1 2 0 0 2 2 2 0 Fungal protein kinase DUF4179 PF13786.6 CDJ67540.1 - 5.6 7.5 0.0 5.6 7.5 0.0 4.9 5 1 0 5 5 2 0 Domain of unknown function (DUF4179) CDC45 PF02724.14 CDJ67540.1 - 6.2 5.0 17.0 1 7.6 0.6 2.1 2 0 0 2 2 2 0 CDC45-like protein Pal1 PF08316.11 CDJ67540.1 - 8.1 7.2 10.4 5.9 7.7 0.2 2.6 2 0 0 2 2 2 0 Pal1 cell morphology protein Gti1_Pac2 PF09729.9 CDJ67540.1 - 8.4 6.4 19.6 1.3 9.0 0.4 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family zf-NPL4 PF05020.15 CDJ67541.1 - 0.0093 16.1 0.3 0.017 15.2 0.3 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region SSP160 PF06933.11 CDJ67542.1 - 9.1 4.3 10.1 12 3.9 10.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PPP4R2 PF09184.11 CDJ67544.1 - 0.4 10.2 7.5 0.49 9.9 7.5 1.1 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 CDJ67544.1 - 5.1 7.0 54.0 6 6.7 54.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 CDJ67545.1 - 0.019 15.0 12.0 0.021 14.9 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 CDJ67545.1 - 0.06 12.5 26.3 0.079 12.1 26.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ67545.1 - 0.17 12.2 29.8 0.16 12.3 29.0 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA FSA_C PF10479.9 CDJ67545.1 - 0.28 9.3 5.4 0.33 9.0 5.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Herpes_glycop PF01528.16 CDJ67545.1 - 1.7 7.4 4.0 2.1 7.1 4.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Ndc1_Nup PF09531.10 CDJ67545.1 - 1.8 7.2 7.4 1.9 7.1 7.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM199X PF15814.5 CDJ67545.1 - 2.7 7.0 13.0 3.9 6.5 13.0 1.3 1 0 0 1 1 1 0 Protein family FAM199X DUF3138 PF11336.8 CDJ67545.1 - 7.4 5.1 13.7 8.2 4.9 13.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spt20 PF12090.8 CDJ67545.1 - 8.4 5.9 15.3 0.74 9.4 11.2 1.4 2 0 0 2 2 2 0 Spt20 family SPX PF03105.19 CDJ67546.1 - 0.42 10.5 17.8 0.0041 17.1 6.6 2.7 1 1 1 2 2 2 0 SPX domain TFIIA PF03153.13 CDJ67547.1 - 0.066 13.2 16.4 0.087 12.8 16.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dfp1_Him1_M PF08630.10 CDJ67547.1 - 0.15 12.3 3.6 0.28 11.4 3.6 1.5 1 0 0 1 1 1 0 Dfp1/Him1, central region DUF2722 PF10846.8 CDJ67548.1 - 0.0078 15.2 3.0 0.0078 15.2 3.0 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) SARAF PF06682.12 CDJ67548.1 - 9.1 5.8 29.7 8.8 5.9 7.7 2.4 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Aldedh PF00171.22 CDJ67549.1 - 2.6e-06 26.2 0.1 5.1e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TFIIA PF03153.13 CDJ67549.1 - 0.0014 18.7 16.4 0.0017 18.4 16.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ67549.1 - 0.0043 16.7 15.4 0.0077 15.9 15.4 1.4 1 0 0 1 1 1 1 Spt20 family DUF1645 PF07816.11 CDJ67549.1 - 0.015 15.9 3.4 0.015 15.9 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Apt1 PF10351.9 CDJ67549.1 - 0.13 11.1 7.7 0.042 12.7 3.6 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4834 PF16118.5 CDJ67549.1 - 0.25 12.3 8.8 3.7 8.6 3.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3446 PF11928.8 CDJ67549.1 - 0.51 10.7 40.3 0.86 9.9 13.5 3.4 3 0 0 3 3 3 0 Early growth response N-terminal domain MAP65_ASE1 PF03999.12 CDJ67549.1 - 0.55 8.9 5.4 1.1 7.9 5.4 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Lin-8 PF03353.15 CDJ67549.1 - 0.67 9.5 12.9 0.027 14.0 6.7 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist IMUP PF15761.5 CDJ67549.1 - 0.85 10.3 32.0 0.85 10.3 11.5 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein Presenilin PF01080.17 CDJ67549.1 - 0.96 8.1 5.0 1.6 7.4 5.0 1.3 1 0 0 1 1 1 0 Presenilin IER PF05760.12 CDJ67549.1 - 2.2 8.5 13.8 2.4 8.4 10.6 2.4 2 1 0 3 3 3 0 Immediate early response protein (IER) Senescence_reg PF04520.13 CDJ67549.1 - 2.2 9.1 12.3 0.57 11.0 7.7 2.1 2 0 0 2 2 2 0 Senescence regulator FNIP_N PF14636.6 CDJ67549.1 - 2.3 9.2 12.8 3.4 8.6 9.5 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus DUF4050 PF13259.6 CDJ67549.1 - 2.4 8.5 7.6 3 8.1 5.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) RAB3GAP2_N PF14655.6 CDJ67549.1 - 6.4 5.9 9.6 0.6 9.3 4.7 1.7 1 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DivIC PF04977.15 CDJ67549.1 - 7 6.5 10.0 13 5.7 10.0 1.4 1 0 0 1 1 1 0 Septum formation initiator ANAPC_CDC26 PF10471.9 CDJ67550.1 - 0.036 14.9 9.9 0.036 14.9 9.9 3.2 2 1 0 2 2 1 0 Anaphase-promoting complex APC subunit CDC26 GTSE1_N PF15259.6 CDJ67550.1 - 0.036 14.2 1.1 0.036 14.2 1.1 2.8 2 1 0 2 2 2 0 G-2 and S-phase expressed 1 Calici_coat_C PF08435.11 CDJ67550.1 - 0.1 12.1 2.8 1.4 8.3 0.2 2.2 2 0 0 2 2 2 0 Calicivirus coat protein C-terminal MDM1 PF15501.6 CDJ67550.1 - 0.19 10.8 24.5 0.026 13.7 15.7 2.0 2 0 0 2 2 2 0 Nuclear protein MDM1 DUF4050 PF13259.6 CDJ67550.1 - 0.5 10.7 15.4 0.47 10.8 8.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Inj_translocase PF16928.5 CDJ67550.1 - 2 7.8 26.4 2.7 7.4 8.2 2.1 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome WBP-1 PF11669.8 CDJ67550.1 - 3.2 8.5 7.2 6.3 7.5 0.8 2.3 2 0 0 2 2 2 0 WW domain-binding protein 1 SR-25 PF10500.9 CDJ67550.1 - 3.5 7.2 27.7 3.1 7.3 22.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 CDJ67550.1 - 4.2 7.0 19.3 2.4 7.9 11.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Med15 PF09606.10 CDJ67550.1 - 4.5 5.8 37.7 12 4.4 37.9 1.6 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Lin-8 PF03353.15 CDJ67550.1 - 7.9 5.9 25.1 4.4 6.8 2.3 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ67550.1 - 9.9 6.0 23.5 9.3 6.1 16.0 2.0 2 0 0 2 2 2 0 SPX domain RT_RNaseH_2 PF17919.1 CDJ67551.1 - 3.7e-26 91.1 0.0 8.8e-26 89.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ67551.1 - 2.1e-16 60.1 0.0 5.4e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ67551.1 - 5.2e-15 55.3 1.4 9.2e-15 54.5 1.4 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ67551.1 - 2.7e-05 24.3 1.1 5.1e-05 23.4 1.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 CDJ67551.1 - 0.013 15.7 0.1 0.052 13.7 0.1 2.0 2 0 0 2 2 2 0 Integrase core domain Scramblase PF03803.15 CDJ67551.1 - 0.07 12.4 0.0 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 Scramblase FAM92 PF06730.11 CDJ67551.1 - 0.13 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 FAM92 protein UPF0051 PF01458.17 CDJ67552.1 - 2.6e-45 154.8 0.0 4e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Med17 PF10156.9 CDJ67552.1 - 0.0013 17.5 0.1 0.0021 16.8 0.1 1.3 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PRIMA1 PF16101.5 CDJ67553.1 - 1.1 9.3 8.2 4 7.5 8.2 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Peptidase_S8 PF00082.22 CDJ67554.1 - 4.1e-42 144.5 5.7 4.1e-42 144.5 5.7 2.0 2 0 0 2 2 2 1 Subtilase family DUF308 PF03729.13 CDJ67554.1 - 0.16 12.3 0.3 2.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) LMBR1 PF04791.16 CDJ67555.1 - 3e-08 33.0 1.2 3.7e-08 32.7 0.0 1.7 2 1 0 2 2 2 1 LMBR1-like membrane protein DUF4381 PF14316.6 CDJ67555.1 - 0.0093 16.2 11.8 0.055 13.7 0.1 4.1 5 0 0 5 5 5 2 Domain of unknown function (DUF4381) DUF1180 PF06679.12 CDJ67555.1 - 0.7 10.3 12.5 0.17 12.3 1.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) SieB PF14163.6 CDJ67555.1 - 9.1 5.8 5.4 78 2.7 0.0 3.5 4 0 0 4 4 4 0 Super-infection exclusion protein B DUF2975 PF11188.8 CDJ67556.1 - 0.021 14.7 0.6 0.079 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) LapA_dom PF06305.11 CDJ67556.1 - 0.031 14.1 0.0 0.031 14.1 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain TMEM100 PF16311.5 CDJ67556.1 - 0.04 13.5 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 DUF4064 PF13273.6 CDJ67556.1 - 0.074 13.3 0.1 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Ninjurin PF04923.12 CDJ67556.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Ninjurin SIT PF15330.6 CDJ67556.1 - 0.19 12.1 0.7 0.39 11.2 0.7 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4658 PF15555.6 CDJ67556.1 - 0.24 11.5 0.1 0.24 11.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) zf-RING_2 PF13639.6 CDJ67557.1 - 3.4e-09 36.9 11.8 6.9e-09 35.9 11.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CDJ67557.1 - 3.4e-06 27.2 9.7 8.5e-06 26.0 9.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CDJ67557.1 - 3.7e-06 26.6 0.8 8.6e-06 25.4 0.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDJ67557.1 - 2.1e-05 24.3 11.0 4.2e-05 23.3 11.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ67557.1 - 0.00031 20.5 6.1 0.00073 19.3 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ67557.1 - 0.00062 19.7 2.7 0.0015 18.5 2.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ67557.1 - 0.0019 18.0 7.8 0.0038 17.0 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ67557.1 - 0.0064 16.4 9.3 0.013 15.5 9.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CDJ67557.1 - 0.017 14.7 9.8 0.04 13.5 9.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CDJ67557.1 - 0.059 13.4 4.8 0.11 12.5 4.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 CDJ67557.1 - 0.11 12.7 6.7 0.24 11.6 6.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 CDJ67557.1 - 2.2 8.4 7.1 5.3 7.2 7.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING-like PF08746.11 CDJ67557.1 - 5.8 7.3 8.5 12 6.3 8.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 CDJ67557.1 - 7.7 6.4 8.4 17 5.3 8.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain EMG1 PF03587.14 CDJ67560.1 - 1.1e-45 155.8 0.1 1.3e-45 155.4 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DEAD PF00270.29 CDJ67561.1 - 8.9e-35 120.0 0.0 1.9e-31 109.2 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ67561.1 - 3.5e-25 88.5 0.0 8.1e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ67561.1 - 2.8e-05 24.2 0.0 7.4e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ67561.1 - 0.017 15.4 0.0 3.1 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain RES PF08808.11 CDJ67561.1 - 0.075 12.9 1.5 0.13 12.2 0.1 2.2 3 0 0 3 3 3 0 RES domain Peptidase_M41 PF01434.18 CDJ67562.1 - 5.9e-53 179.5 1.6 1.2e-52 178.6 0.0 2.4 4 0 0 4 4 4 1 Peptidase family M41 AAA PF00004.29 CDJ67562.1 - 1.1e-41 142.3 0.0 2.2e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ67562.1 - 7.2e-13 48.1 0.5 1.7e-12 47.0 0.5 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CDJ67562.1 - 0.0002 21.7 0.1 0.15 12.3 0.0 3.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CDJ67562.1 - 0.00049 19.4 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CDJ67562.1 - 0.0028 17.7 0.0 0.01 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ67562.1 - 0.0052 17.2 4.2 0.0086 16.5 0.2 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 CDJ67562.1 - 0.0061 17.1 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ67562.1 - 0.0086 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CDJ67562.1 - 0.023 14.1 0.5 0.15 11.5 0.2 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CDJ67562.1 - 0.024 14.4 0.0 0.08 12.7 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 CDJ67562.1 - 0.037 14.2 1.4 0.07 13.3 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 CDJ67562.1 - 0.08 13.4 0.0 0.25 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 CDJ67562.1 - 0.13 12.4 0.0 0.48 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 CDJ67562.1 - 0.43 10.8 0.0 0.43 10.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 CDJ67562.1 - 0.72 9.5 5.4 0.24 11.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain Pex14_N PF04695.13 CDJ67562.1 - 5.8 7.6 16.3 0.58 10.8 6.2 3.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyoxalase PF00903.25 CDJ67563.1 - 3.1e-12 46.8 0.0 1.2e-08 35.2 0.0 3.0 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CDJ67563.1 - 0.00019 21.7 0.0 0.066 13.5 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DGF-1_C PF11040.8 CDJ67564.1 - 0.094 12.7 3.5 0.39 10.7 3.5 2.0 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Peptidase_S21 PF00716.17 CDJ67564.1 - 1.2 8.8 8.7 2.4 7.8 8.7 1.5 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) DGF-1_C PF11040.8 CDJ67565.1 - 0.6 10.2 7.5 0.096 12.7 3.4 1.8 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus ABC_tran PF00005.27 CDJ67567.1 - 5.2e-24 85.3 0.0 8.3e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CDJ67567.1 - 4.2e-18 65.5 17.0 9.2e-18 64.4 17.0 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CDJ67567.1 - 1.1e-08 34.5 12.0 1.7e-08 34.0 12.0 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ67567.1 - 2.8e-05 24.1 0.2 0.017 14.9 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDJ67567.1 - 0.00011 22.1 0.2 0.0002 21.3 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CDJ67567.1 - 0.00023 21.6 0.0 0.00053 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CDJ67567.1 - 0.0015 18.3 0.2 0.0033 17.1 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ67567.1 - 0.0031 17.6 0.0 0.0061 16.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 CDJ67567.1 - 0.0033 17.0 0.1 0.0069 16.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDJ67567.1 - 0.0039 17.7 0.0 0.0084 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CDJ67567.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF87 PF01935.17 CDJ67567.1 - 0.015 15.4 0.3 0.03 14.4 0.3 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain MeaB PF03308.16 CDJ67567.1 - 0.034 13.1 0.9 0.054 12.5 0.2 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC2_membrane_2 PF12679.7 CDJ67567.1 - 0.045 13.0 5.2 0.066 12.5 5.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_28 PF13521.6 CDJ67567.1 - 0.048 13.9 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ67567.1 - 0.049 12.9 0.1 0.099 11.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 CDJ67567.1 - 0.056 13.2 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 CDJ67567.1 - 0.2 11.1 0.0 4.3 6.7 0.0 2.1 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain SF3A2 PF16835.5 CDJ67568.1 - 8.5e-36 122.2 0.0 1.3e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CDJ67568.1 - 3.3e-07 30.5 1.4 6.1e-07 29.6 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 CDJ67568.1 - 0.0093 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PPR PF01535.20 CDJ67569.1 - 2e-14 52.7 1.8 0.00057 20.0 0.1 6.3 7 0 0 7 7 7 2 PPR repeat PPR_2 PF13041.6 CDJ67569.1 - 1.7e-13 50.5 0.0 9.4e-06 25.7 0.0 4.4 3 1 2 5 5 5 2 PPR repeat family PPR_long PF17177.4 CDJ67569.1 - 2.2e-05 23.9 0.0 2.2e-05 23.9 0.0 3.9 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CDJ67569.1 - 4.6e-05 23.4 0.0 0.83 9.8 0.0 5.1 5 1 1 6 6 6 2 Pentatricopeptide repeat domain PrpF PF04303.13 CDJ67569.1 - 0.14 11.1 2.0 0.29 10.0 2.0 1.5 1 0 0 1 1 1 0 PrpF protein TPR_7 PF13176.6 CDJ67569.1 - 0.52 10.5 5.4 4.4 7.6 0.1 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat YjbH PF06082.11 CDJ67569.1 - 1.2 7.9 11.6 0.029 13.2 4.8 1.7 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH Vac14_Fab1_bd PF12755.7 CDJ67570.1 - 2.1e-32 111.6 0.0 1.6e-28 99.2 0.0 3.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.8 CDJ67570.1 - 4.9e-17 62.2 0.0 1.3e-16 60.8 0.0 1.7 1 1 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.22 CDJ67570.1 - 2.6e-10 39.6 0.4 0.018 15.3 0.0 5.2 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 CDJ67570.1 - 0.00055 20.3 3.1 0.57 10.6 0.3 5.3 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 CDJ67570.1 - 0.0024 18.3 9.5 0.19 12.2 0.0 5.0 5 0 0 5 5 5 2 HEAT-like repeat Tti2 PF10521.9 CDJ67570.1 - 0.013 15.0 0.6 0.73 9.3 0.0 3.3 3 0 0 3 3 3 0 Tti2 family P16-Arc PF04699.14 CDJ67570.1 - 6.4 7.3 7.4 34 4.9 0.6 4.0 3 0 0 3 3 3 0 ARP2/3 complex 16 kDa subunit (p16-Arc) ubiquitin PF00240.23 CDJ67571.1 - 2.6e-34 116.8 0.3 3.6e-34 116.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CDJ67571.1 - 5.9e-30 102.9 11.2 9e-30 102.3 11.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CDJ67571.1 - 6.8e-17 61.1 0.5 1e-16 60.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ67571.1 - 3.3e-06 27.5 0.1 1.2e-05 25.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ67571.1 - 0.004 17.1 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ67571.1 - 0.011 16.1 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ67571.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDJ67571.1 - 0.025 14.6 0.8 5.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CDJ67571.1 - 0.044 14.4 0.0 0.053 14.1 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain U-box PF04564.15 CDJ67573.1 - 1.7e-18 66.5 0.0 3.5e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 CDJ67573.1 - 1.4e-10 40.5 7.7 0.0014 18.4 1.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ67573.1 - 7.2e-10 38.2 8.9 0.0075 16.3 1.8 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ67573.1 - 8.8e-07 28.7 7.3 0.016 15.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ67573.1 - 1.2e-05 25.8 5.9 0.0002 21.9 1.9 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ67573.1 - 4.1e-05 23.7 1.3 7.6e-05 22.9 1.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CDJ67573.1 - 8.5e-05 22.6 3.1 0.00036 20.6 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ67573.1 - 0.005 17.1 12.9 0.048 14.0 1.3 3.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ67573.1 - 0.015 15.0 7.5 2.1 8.1 1.3 3.2 1 1 2 3 3 3 0 TPR repeat zf-NOSIP PF15906.5 CDJ67573.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_19 PF14559.6 CDJ67573.1 - 0.025 15.1 4.5 0.067 13.7 2.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ67573.1 - 1.2 10.2 10.6 3.9 8.6 0.0 4.3 2 2 3 5 5 5 0 Tetratricopeptide repeat EGF_2 PF07974.13 CDJ67574.1 - 0.48 10.8 37.6 0.24 11.8 6.6 4.0 3 0 0 3 3 3 0 EGF-like domain CBM_19 PF03427.13 CDJ67576.1 - 0.17 11.9 0.2 0.27 11.3 0.2 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) FUSC PF04632.12 CDJ67576.1 - 0.6 8.6 4.2 0.62 8.5 4.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Radial_spoke_3 PF06098.11 CDJ67579.1 - 1.1e-07 31.5 11.3 1.1e-07 31.5 11.3 1.7 2 0 0 2 2 2 1 Radial spoke protein 3 DUF842 PF05811.13 CDJ67579.1 - 0.014 15.1 0.8 0.04 13.6 0.0 2.1 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) DUF2335 PF10097.9 CDJ67579.1 - 1.6 8.7 0.0 1.6 8.7 0.0 3.8 3 1 0 3 3 3 0 Predicted membrane protein (DUF2335) TRM13 PF05206.14 CDJ67580.1 - 7e-07 29.0 5.3 0.00056 19.5 0.0 3.9 4 1 1 5 5 5 2 Methyltransferase TRM13 zf-U11-48K PF05253.12 CDJ67580.1 - 3.8e-06 26.7 0.2 9.3e-06 25.4 0.2 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger TFB6 PF17110.5 CDJ67580.1 - 0.57 9.9 3.0 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH FAD-oxidase_C PF02913.19 CDJ67581.1 - 1.5e-38 132.9 0.0 2.2e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CDJ67581.1 - 2.3e-33 114.8 0.3 4e-33 114.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain SNARE_assoc PF09335.11 CDJ67582.1 - 4.3e-14 53.0 8.2 4.3e-14 53.0 8.2 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF3087 PF11286.8 CDJ67582.1 - 0.39 10.2 2.3 5.9 6.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) DUF3995 PF13160.6 CDJ67582.1 - 6 7.2 12.3 0.26 11.6 4.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3995) MKT1_C PF12246.8 CDJ67584.1 - 1.4e-33 116.2 0.0 2.2e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CDJ67584.1 - 1.3e-08 35.1 0.0 8.8e-07 29.2 0.0 2.8 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 CDJ67584.1 - 7e-07 29.7 0.0 1.5e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CDJ67584.1 - 0.016 15.5 0.0 0.058 13.7 0.0 2.0 2 0 0 2 2 2 0 XPG I-region CCDC24 PF15669.5 CDJ67584.1 - 4.3 7.2 7.6 0.61 9.9 0.1 3.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 24 family FAM221 PF14753.6 CDJ67585.1 - 2.5e-25 89.2 18.4 1.3e-22 80.3 9.2 2.9 2 1 0 2 2 2 2 Protein FAM221A/B SUIM_assoc PF16619.5 CDJ67585.1 - 1.6e-05 24.9 0.6 1.6e-05 24.9 0.6 4.8 3 1 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ67585.1 - 0.0011 18.7 2.8 0.0011 18.7 2.8 3.2 3 0 0 3 3 3 2 Spt20 family DUF2722 PF10846.8 CDJ67585.1 - 0.011 14.8 1.7 0.011 14.8 1.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) GD_AH_C PF04295.13 CDJ67585.1 - 0.067 12.0 6.5 0.49 9.1 2.5 2.3 2 0 0 2 2 2 0 D-galactarate dehydratase / Altronate hydrolase, C terminus EOS1 PF12326.8 CDJ67585.1 - 0.17 11.8 0.0 1.1 9.1 0.0 2.2 1 1 0 1 1 1 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ67585.1 - 1.1 8.2 8.0 1.6 7.6 2.5 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Anp1 PF03452.14 CDJ67585.1 - 8.5 5.7 8.4 41 3.5 5.7 2.1 2 0 0 2 2 2 0 Anp1 TOM13 PF08219.11 CDJ67586.1 - 1.8 8.6 0.0 1.8 8.6 0.0 4.8 7 0 0 7 7 7 0 Outer membrane protein TOM13 RNase_H2_suC PF08615.11 CDJ67587.1 - 0.28 11.3 0.0 0.28 11.3 0.0 3.6 4 1 0 4 4 4 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) S1 PF00575.23 CDJ67588.1 - 0.00088 19.6 0.0 6.9 7.1 0.0 5.9 7 0 0 7 7 7 1 S1 RNA binding domain DUF2722 PF10846.8 CDJ67588.1 - 0.0084 15.1 0.0 0.0084 15.1 0.0 15.6 13 2 0 13 13 13 7 Protein of unknown function (DUF2722) N6_N4_Mtase PF01555.18 CDJ67588.1 - 0.033 13.9 0.0 26 4.4 0.1 3.9 4 1 0 4 4 4 0 DNA methylase TFB6 PF17110.5 CDJ67589.1 - 0.065 13.0 8.5 0.069 12.9 8.5 1.0 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SID-1_RNA_chan PF13965.6 CDJ67589.1 - 0.081 11.3 6.0 0.076 11.4 6.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CPSF100_C PF13299.6 CDJ67589.1 - 0.088 13.0 16.1 0.099 12.8 16.1 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal HA2 PF04408.23 CDJ67589.1 - 0.11 12.8 7.5 0.16 12.3 7.5 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) OATP PF03137.20 CDJ67589.1 - 0.13 10.5 9.5 0.13 10.5 9.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RR_TM4-6 PF06459.12 CDJ67589.1 - 0.14 12.0 16.9 0.14 12.0 16.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ67589.1 - 0.14 10.9 18.5 0.13 11.0 18.5 1.0 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 CDJ67589.1 - 0.22 11.3 13.8 0.24 11.1 13.8 1.0 1 0 0 1 1 1 0 Connexin Ctr PF04145.15 CDJ67589.1 - 0.32 11.6 8.1 0.3 11.7 8.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family SpoIIP PF07454.11 CDJ67589.1 - 0.33 10.4 19.6 0.34 10.3 19.6 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 CDJ67589.1 - 0.36 11.0 16.2 0.34 11.0 16.2 1.0 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ67589.1 - 0.38 9.7 23.5 0.35 9.8 23.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLP1_P PF16575.5 CDJ67589.1 - 0.41 10.4 7.7 0.5 10.1 7.7 1.0 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Pex14_N PF04695.13 CDJ67589.1 - 0.45 11.2 30.2 0.45 11.2 30.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.19 CDJ67589.1 - 0.49 8.3 19.8 0.52 8.2 19.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GNAT_acetyltr_2 PF13718.6 CDJ67589.1 - 0.49 9.8 10.4 0.51 9.7 10.4 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 RIC3 PF15361.6 CDJ67589.1 - 0.59 10.5 14.9 0.68 10.3 14.9 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Neur_chan_memb PF02932.16 CDJ67589.1 - 0.86 9.6 16.7 0.95 9.5 16.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM176 PF14851.6 CDJ67589.1 - 0.99 9.1 10.6 1.1 8.9 10.6 1.1 1 0 0 1 1 1 0 FAM176 family DUF3408 PF11888.8 CDJ67589.1 - 1.2 9.3 18.1 1.2 9.2 18.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) CLN3 PF02487.17 CDJ67589.1 - 1.3 8.0 14.3 1.3 7.9 14.3 1.0 1 0 0 1 1 1 0 CLN3 protein AIF_C PF14721.6 CDJ67589.1 - 1.3 9.4 14.4 1.4 9.3 14.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Trp_oprn_chp PF09534.10 CDJ67589.1 - 1.3 8.8 7.0 2.6 7.8 7.0 1.6 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Band_3_cyto PF07565.13 CDJ67589.1 - 1.5 8.5 16.7 1.5 8.6 16.7 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CobT PF06213.12 CDJ67589.1 - 1.5 8.1 28.1 1.6 8.0 28.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 CDJ67589.1 - 1.7 7.6 12.6 1.7 7.5 12.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Eapp_C PF10238.9 CDJ67589.1 - 1.7 8.7 19.4 1.8 8.6 19.4 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein Rxt3 PF08642.10 CDJ67589.1 - 1.8 9.3 9.6 2.3 9.0 9.6 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 FAM60A PF15396.6 CDJ67589.1 - 1.9 8.4 13.1 1.9 8.4 13.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Paf1 PF03985.13 CDJ67589.1 - 2 7.3 21.1 2.1 7.3 21.1 1.0 1 0 0 1 1 1 0 Paf1 Peptidase_U57 PF05582.12 CDJ67589.1 - 2.2 7.5 14.0 2.2 7.4 14.0 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF4746 PF15928.5 CDJ67589.1 - 2.2 7.6 13.2 2.2 7.7 13.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) UPF0239 PF06783.11 CDJ67589.1 - 2.3 8.5 10.9 2.9 8.2 10.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) AMP-binding PF00501.28 CDJ67589.1 - 2.3 6.7 6.8 2.4 6.7 6.8 1.0 1 0 0 1 1 1 0 AMP-binding enzyme Serinc PF03348.15 CDJ67589.1 - 2.8 6.8 12.2 2.7 6.8 12.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Folate_carrier PF01770.18 CDJ67589.1 - 3 6.5 11.2 3.2 6.4 11.2 1.0 1 0 0 1 1 1 0 Reduced folate carrier Baculo_PP31 PF05311.11 CDJ67589.1 - 3.1 7.2 19.3 3.3 7.1 19.3 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CBP_BcsG PF11658.8 CDJ67589.1 - 3.1 6.1 15.4 3.4 6.0 15.4 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG SLC12 PF03522.15 CDJ67589.1 - 3.4 6.6 18.3 3.4 6.6 18.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FHIPEP PF00771.20 CDJ67589.1 - 3.4 6.0 12.6 4 5.8 12.6 1.2 1 0 0 1 1 1 0 FHIPEP family CCDC53 PF10152.9 CDJ67589.1 - 3.7 8.0 21.1 3.9 7.9 21.1 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex ALMT PF11744.8 CDJ67589.1 - 3.7 6.3 15.2 3.9 6.2 15.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 CDJ67589.1 - 3.8 7.4 47.7 3.8 7.4 47.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 CDJ67589.1 - 3.9 7.9 22.9 4.1 7.9 22.9 1.1 1 0 0 1 1 1 0 AAA domain HemX PF04375.14 CDJ67589.1 - 4.2 6.6 38.5 4.7 6.4 38.5 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Coilin_N PF15862.5 CDJ67589.1 - 4.2 7.2 22.4 6.4 6.6 22.4 1.4 1 0 0 1 1 1 0 Coilin N-terminus DcuA_DcuB PF03605.14 CDJ67589.1 - 4.4 6.1 7.5 5.1 5.9 7.5 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Cellulose_synt PF03552.14 CDJ67589.1 - 4.4 5.7 7.0 4 5.8 7.0 1.0 1 0 0 1 1 1 0 Cellulose synthase PAT1 PF09770.9 CDJ67589.1 - 4.4 5.5 31.6 4.3 5.5 31.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1980 PF09323.10 CDJ67589.1 - 4.9 7.0 15.1 4.6 7.1 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PPL5 PF18168.1 CDJ67589.1 - 4.9 6.4 14.2 5.2 6.3 14.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Peroxin-13_N PF04088.13 CDJ67589.1 - 5.1 7.4 12.6 6.1 7.1 12.6 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FPN1 PF06963.12 CDJ67589.1 - 5.2 5.5 8.3 5.4 5.5 8.3 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF2126 PF09899.9 CDJ67589.1 - 5.4 5.0 13.9 5 5.1 13.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) G0-G1_switch_2 PF15103.6 CDJ67589.1 - 5.4 7.5 13.6 6.9 7.2 13.6 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 Ureide_permease PF07168.11 CDJ67589.1 - 6 5.5 9.7 5.9 5.5 9.7 1.1 1 0 0 1 1 1 0 Ureide permease Hid1 PF12722.7 CDJ67589.1 - 6 4.9 16.9 5.7 4.9 16.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tim54 PF11711.8 CDJ67589.1 - 6.4 5.5 18.4 6.8 5.4 18.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 CDJ67589.1 - 6.7 5.8 8.4 6 6.0 8.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter YABBY PF04690.13 CDJ67589.1 - 7 7.2 16.3 7.7 7.1 16.3 1.1 1 0 0 1 1 1 0 YABBY protein Peptidase_S15 PF02129.18 CDJ67589.1 - 7.1 6.1 15.9 7.4 6.1 15.9 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3464 PF11947.8 CDJ67589.1 - 7.3 6.3 20.6 8.7 6.1 20.6 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 EOS1 PF12326.8 CDJ67589.1 - 7.6 6.4 11.8 8.1 6.3 11.8 1.1 1 0 0 1 1 1 0 N-glycosylation protein DUF3675 PF12428.8 CDJ67589.1 - 7.8 7.1 6.3 11 6.6 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Orf78 PF06024.12 CDJ67589.1 - 7.9 6.8 12.5 12 6.3 12.5 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF2828 PF11443.8 CDJ67589.1 - 8 4.4 20.8 8.7 4.3 20.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Peptidase_S49_N PF08496.10 CDJ67589.1 - 8.2 6.5 18.2 9.7 6.2 18.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CSG2 PF16965.5 CDJ67589.1 - 9.4 5.1 12.2 9.7 5.0 12.2 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator EIIBC-GUT_N PF03612.14 CDJ67589.1 - 10 5.8 19.5 12 5.6 19.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2722 PF10846.8 CDJ67591.1 - 0.0041 16.1 22.8 0.0041 16.1 22.8 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) Kelch_5 PF13854.6 CDJ67591.1 - 0.0099 15.9 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.15 CDJ67591.1 - 0.013 15.4 0.1 6.3 6.9 0.0 2.4 1 1 1 2 2 2 0 Kelch motif Kelch_1 PF01344.25 CDJ67591.1 - 0.11 12.1 0.1 9.8 5.9 0.1 2.4 1 1 1 2 2 2 0 Kelch motif Gti1_Pac2 PF09729.9 CDJ67591.1 - 3.1 7.8 21.0 4.8 7.2 5.0 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family DUF2052 PF09747.9 CDJ67591.1 - 3.3 7.8 20.9 4.6 7.3 8.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Ephrin_rec_like PF07699.13 CDJ67592.1 - 3.4e-09 36.3 57.0 0.00064 19.4 4.0 7.5 3 1 0 5 5 5 5 Putative ephrin-receptor like TNFR_c6 PF00020.18 CDJ67592.1 - 0.0018 18.6 0.3 0.0018 18.6 0.3 7.6 6 2 2 8 8 8 3 TNFR/NGFR cysteine-rich region Packaging_FI PF14000.6 CDJ67593.1 - 0.014 15.8 0.2 0.046 14.2 0.2 1.8 1 0 0 1 1 1 0 DNA packaging protein FI TPR_1 PF00515.28 CDJ67594.1 - 0.047 13.5 4.7 0.75 9.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ67594.1 - 0.051 13.7 8.0 0.12 12.5 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ67594.1 - 0.052 13.6 0.5 0.35 11.0 0.5 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.22 CDJ67595.1 - 2.3e-14 53.0 0.0 3.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Str_synth PF03088.16 CDJ67596.1 - 7.6e-08 32.4 0.0 3.5e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 CDJ67596.1 - 0.0015 18.2 0.0 0.0053 16.4 0.0 1.9 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Methyltransf_25 PF13649.6 CDJ67597.1 - 2.2e-22 79.6 0.0 8.4e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ67597.1 - 1.6e-21 76.7 0.0 5e-21 75.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ67597.1 - 2e-18 66.8 0.0 3.5e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ67597.1 - 2.8e-16 59.6 0.0 4.5e-16 59.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CDJ67597.1 - 8.4e-14 51.5 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CDJ67597.1 - 1.7e-13 51.2 0.1 9.7e-13 48.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ67597.1 - 3.9e-12 46.0 0.1 8.8e-10 38.3 0.0 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family MTS PF05175.14 CDJ67597.1 - 1.4e-05 24.7 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CDJ67597.1 - 2e-05 24.0 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 CDJ67597.1 - 0.00027 20.5 0.0 0.00096 18.7 0.0 1.7 1 1 1 2 2 2 1 AdoMet dependent proline di-methyltransferase FtsJ PF01728.19 CDJ67597.1 - 0.0015 18.7 0.0 0.052 13.6 0.0 2.7 1 1 1 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.19 CDJ67597.1 - 0.0016 18.2 0.0 0.0065 16.2 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 CDJ67597.1 - 0.0025 17.3 0.0 0.18 11.3 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.11 CDJ67597.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 CDJ67597.1 - 0.013 15.0 0.0 0.043 13.3 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase TPMT PF05724.11 CDJ67597.1 - 0.013 15.1 0.0 0.068 12.8 0.0 2.0 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Reo_sigmaC PF04582.12 CDJ67597.1 - 0.038 14.3 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein C-terminal domain DOT1 PF08123.13 CDJ67597.1 - 0.045 13.3 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.20 CDJ67597.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.13 CDJ67597.1 - 0.087 12.2 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 CDJ67597.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UCH_1 PF13423.6 CDJ67600.1 - 4.5e-08 33.1 0.0 1.4e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TFIIA PF03153.13 CDJ67600.1 - 0.0012 19.0 16.5 0.0014 18.7 16.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 CDJ67600.1 - 0.009 16.2 9.0 0.013 15.6 9.0 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated zf-TFIIIC PF12660.7 CDJ67600.1 - 0.025 14.5 0.1 0.24 11.4 0.1 2.1 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex SPX PF03105.19 CDJ67600.1 - 0.057 13.3 5.9 0.065 13.1 5.9 1.2 1 0 0 1 1 1 0 SPX domain Velvet PF11754.8 CDJ67600.1 - 0.074 13.0 8.1 0.097 12.6 8.1 1.2 1 0 0 1 1 1 0 Velvet factor Ndc1_Nup PF09531.10 CDJ67600.1 - 0.26 9.9 9.3 0.34 9.6 9.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EPL1 PF10513.9 CDJ67600.1 - 0.3 11.5 3.5 0.46 10.9 3.5 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Suf PF05843.14 CDJ67600.1 - 0.4 10.6 7.1 0.51 10.3 7.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.12 CDJ67600.1 - 0.55 10.0 4.3 0.75 9.6 4.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM199X PF15814.5 CDJ67600.1 - 0.78 8.7 12.2 1.3 8.0 12.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X Presenilin PF01080.17 CDJ67600.1 - 0.99 8.1 6.9 1.3 7.7 6.9 1.1 1 0 0 1 1 1 0 Presenilin SPG4 PF17325.2 CDJ67600.1 - 1.3 10.1 6.3 0.31 12.1 2.1 1.9 2 0 0 2 2 2 0 Stationary phase protein 4 SR-25 PF10500.9 CDJ67600.1 - 1.4 8.5 24.7 2.9 7.4 24.7 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 CDJ67600.1 - 2.2 5.3 8.1 2.5 5.1 8.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NAM-associated PF14303.6 CDJ67600.1 - 3.1 8.5 11.5 6.4 7.5 11.5 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Hid1 PF12722.7 CDJ67600.1 - 7.4 4.6 6.7 9 4.3 6.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SWI-SNF_Ssr4 PF08549.10 CDJ67600.1 - 7.8 5.0 12.2 12 4.4 12.2 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Eapp_C PF10238.9 CDJ67600.1 - 10 6.2 12.4 5.4 7.1 10.0 1.7 1 1 1 2 2 2 0 E2F-associated phosphoprotein Glyco_transf_9 PF01075.17 CDJ67602.1 - 0.013 14.8 1.0 0.015 14.7 1.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Nitroreductase PF00881.24 CDJ67602.1 - 0.028 14.5 0.9 0.029 14.4 0.9 1.3 1 1 0 1 1 1 0 Nitroreductase family Roughex PF06020.11 CDJ67602.1 - 0.064 12.3 8.1 0.08 12.0 8.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF4834 PF16118.5 CDJ67602.1 - 0.11 13.4 1.7 0.16 12.9 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ67602.1 - 0.12 11.3 13.7 0.16 10.8 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ67602.1 - 0.23 11.4 17.5 0.24 11.4 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fer4_13 PF13370.6 CDJ67602.1 - 0.43 11.2 3.1 0.9 10.1 3.1 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I ERCC4 PF02732.15 CDJ67602.1 - 0.95 9.7 5.1 1.1 9.4 5.1 1.3 1 1 0 1 1 1 0 ERCC4 domain Suf PF05843.14 CDJ67602.1 - 1.1 9.1 7.3 1.3 9.0 7.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MFS_2 PF13347.6 CDJ67603.1 - 3.4e-24 85.2 9.2 2e-15 56.3 1.0 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein DUF2768 PF10966.8 CDJ67603.1 - 0.015 15.7 6.1 1 9.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) Chromo PF00385.24 CDJ67604.1 - 6.8e-12 45.1 0.0 1.6e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CDJ67604.1 - 2.1e-08 34.4 0.0 3.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ67604.1 - 0.012 15.3 0.1 0.033 14.0 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain RT_RNaseH_2 PF17919.1 CDJ67605.1 - 3.6e-29 100.8 0.0 6.2e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ67605.1 - 9.4e-19 67.7 0.0 1.8e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ67605.1 - 3.5e-15 56.1 0.0 5.9e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S8_N PF16361.5 CDJ67606.1 - 0.016 15.7 1.7 0.016 15.7 1.7 2.3 2 1 0 2 2 2 0 N-terminal of Subtilase family Spt20 PF12090.8 CDJ67606.1 - 0.024 14.2 6.9 0.037 13.6 6.9 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ67606.1 - 0.41 10.7 12.1 0.2 11.7 7.9 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-A20 PF01754.16 CDJ67607.1 - 1.3e-11 44.2 7.5 1.3e-11 44.2 7.5 2.4 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 CDJ67607.1 - 2.1e-08 34.2 8.8 2.1e-08 34.2 8.8 2.2 2 0 0 2 2 2 1 AN1-like Zinc finger DUF4428 PF14471.6 CDJ67607.1 - 0.38 10.7 3.6 5.8 6.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) NUP50 PF08911.11 CDJ67608.1 - 0.012 16.2 3.4 0.046 14.4 3.4 2.1 1 1 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) NUDE_C PF04880.13 CDJ67608.1 - 0.024 15.1 7.1 0.055 14.0 7.1 1.7 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PRRSV_Env PF02340.15 CDJ67609.1 - 0.0057 16.1 0.0 0.027 13.8 0.0 2.0 2 0 0 2 2 2 1 PRRSV putative envelope protein Gene66 PF02053.15 CDJ67609.1 - 0.029 14.0 0.1 0.066 12.8 0.1 1.5 1 0 0 1 1 1 0 Gene 66 (IR5) protein AAA_18 PF13238.6 CDJ67609.1 - 0.083 13.4 0.0 0.24 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TFIID_30kDa PF03540.13 CDJ67611.1 - 3.2e-07 30.2 0.1 5.4e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Prefoldin PF02996.17 CDJ67612.1 - 4.5e-18 65.3 2.1 6.1e-18 64.9 2.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit YugN PF08868.10 CDJ67612.1 - 0.077 12.9 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 YugN-like family Fib_alpha PF08702.10 CDJ67612.1 - 0.12 12.5 3.3 1 9.6 0.6 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec2p PF06428.11 CDJ67612.1 - 0.17 11.9 3.1 1.4 8.9 0.2 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p XhlA PF10779.9 CDJ67612.1 - 0.25 11.6 1.1 0.67 10.2 0.0 2.0 2 0 0 2 2 2 0 Haemolysin XhlA V-SNARE PF05008.15 CDJ67612.1 - 2.5 8.5 7.7 0.62 10.5 0.7 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus PspB PF06667.12 CDJ67616.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Phage shock protein B IMUP PF15761.5 CDJ67618.1 - 0.044 14.5 2.6 0.081 13.6 2.6 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Wzy_C_2 PF11846.8 CDJ67620.1 - 0.034 14.1 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal RVP_2 PF08284.11 CDJ67621.1 - 4.2e-11 42.8 0.0 6.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ67621.1 - 1.7e-08 34.9 0.0 4.9e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ67621.1 - 2.2e-08 34.6 0.0 1e-07 32.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 CDJ67621.1 - 0.00064 20.0 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ67621.1 - 0.037 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF4027 PF13219.6 CDJ67621.1 - 0.24 11.3 0.2 20 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) TDRP PF15683.5 CDJ67623.1 - 1.7 8.6 12.0 0.95 9.4 8.5 2.3 2 0 0 2 2 2 0 Testis development-related protein Surface_antigen PF11054.8 CDJ67626.1 - 1.6e-12 47.6 17.9 1.5e-09 37.9 5.4 4.8 3 3 2 5 5 5 3 Sporozoite TA4 surface antigen SPT2 PF08243.11 CDJ67627.1 - 3.2e-09 37.3 12.9 3.2e-09 37.3 12.9 7.1 7 2 2 9 9 9 1 SPT2 chromatin protein Nckap1 PF09735.9 CDJ67628.1 - 0.67 7.8 4.7 0.91 7.4 4.7 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein DNA_pol3_a_NII PF11490.8 CDJ67628.1 - 6.8 6.6 9.1 11 6.0 2.9 2.3 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II Peptidase_C54 PF03416.19 CDJ67629.1 - 3.4e-12 46.4 0.0 1.1e-11 44.7 0.0 1.9 1 0 0 1 1 1 1 Peptidase family C54 SR-25 PF10500.9 CDJ67629.1 - 0.0019 17.9 11.2 0.0019 17.9 11.2 15.1 12 4 1 14 14 14 3 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ67629.1 - 0.032 14.5 0.0 0.032 14.5 0.0 16.5 6 4 4 11 11 11 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ67630.1 - 0.028 14.7 0.0 0.028 14.7 0.0 13.9 4 3 4 9 9 9 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ67631.1 - 0.013 15.2 14.6 0.015 15.0 14.6 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ67631.1 - 0.029 13.3 9.0 0.034 13.1 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ67631.1 - 0.039 14.0 19.1 0.046 13.7 19.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dicty_REP PF05086.12 CDJ67631.1 - 0.21 9.5 2.3 0.21 9.5 2.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PPL5 PF18168.1 CDJ67631.1 - 0.33 10.2 3.5 0.43 9.8 3.5 1.1 1 0 0 1 1 1 0 Prim-pol family 5 SARAF PF06682.12 CDJ67631.1 - 0.36 10.4 8.9 0.4 10.3 8.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Neur_chan_memb PF02932.16 CDJ67631.1 - 0.88 9.6 3.4 0.99 9.4 3.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Alpha_GJ PF03229.13 CDJ67631.1 - 1.8 9.2 20.7 3.5 8.2 3.1 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J Presenilin PF01080.17 CDJ67631.1 - 3.5 6.3 10.1 4 6.1 10.1 1.1 1 0 0 1 1 1 0 Presenilin eIF3_subunit PF08597.10 CDJ67631.1 - 8.9 6.1 17.1 17 5.2 17.1 1.5 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit Spt20 PF12090.8 CDJ67633.1 - 0.0059 16.3 1.1 0.0059 16.3 1.1 2.9 2 1 0 2 2 2 1 Spt20 family Hamartin PF04388.12 CDJ67633.1 - 1.1 7.8 19.4 3.9 6.0 19.7 1.5 1 1 0 1 1 1 0 Hamartin protein Utp14 PF04615.13 CDJ67633.1 - 1.5 7.3 14.0 2.3 6.7 14.0 1.3 1 0 0 1 1 1 0 Utp14 protein eIF-3_zeta PF05091.12 CDJ67633.1 - 3.5 6.5 10.0 0.27 10.2 2.5 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Retrotrans_gag PF03732.17 CDJ67634.1 - 0.075 13.3 0.1 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein ZinT PF09223.11 CDJ67634.1 - 0.092 12.6 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment DUF3552 PF12072.8 CDJ67635.1 - 0.018 14.5 0.3 0.018 14.5 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) MFS_2 PF13347.6 CDJ67636.1 - 1.8e-23 82.8 1.2 2.1e-23 82.6 1.2 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 CDJ67636.1 - 0.0018 17.3 0.4 0.0023 16.9 0.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RRF PF01765.19 CDJ67637.1 - 2.7e-13 50.2 5.1 3.2e-13 50.0 5.1 1.0 1 0 0 1 1 1 1 Ribosome recycling factor DUF2103 PF09876.9 CDJ67637.1 - 0.019 14.9 0.9 0.035 14.1 0.9 1.4 1 1 0 1 1 1 0 Predicted metal-binding protein (DUF2103) SpoIIIAH PF12685.7 CDJ67637.1 - 0.025 14.4 6.2 0.029 14.2 6.2 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4201 PF13870.6 CDJ67638.1 - 0.015 15.1 0.1 0.018 14.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Macoilin PF09726.9 CDJ67638.1 - 0.15 10.6 15.1 0.17 10.4 15.1 1.1 1 0 0 1 1 1 0 Macoilin family CCDC85 PF10226.9 CDJ67638.1 - 0.41 10.3 10.2 0.57 9.8 10.2 1.3 1 1 0 1 1 1 0 CCDC85 family Apt1 PF10351.9 CDJ67638.1 - 7.9 5.2 13.2 9.1 5.0 13.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TetR_C_35 PF18556.1 CDJ67641.1 - 0.0044 17.1 2.1 0.01 16.0 0.4 2.0 2 0 0 2 2 2 1 Bacterial Tetracyclin repressor, C-terminal domain Tetraspanin PF00335.20 CDJ67641.1 - 0.016 14.9 0.2 0.021 14.6 0.2 1.5 1 1 0 1 1 1 0 Tetraspanin family SUIM_assoc PF16619.5 CDJ67641.1 - 0.033 14.3 14.0 0.043 13.9 0.2 2.4 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ThrE PF06738.12 CDJ67641.1 - 2.2 7.6 7.3 3.4 7.0 7.3 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter Phage_holin_3_6 PF07332.11 CDJ67641.1 - 9.1 6.4 14.2 20 5.3 14.2 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PRMT5 PF05185.16 CDJ67642.1 - 5.5e-32 111.0 0.1 6.4e-16 58.7 0.0 3.3 2 1 0 2 2 2 2 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CDJ67642.1 - 1e-28 100.4 0.0 1.9e-27 96.2 0.0 2.6 2 1 0 2 2 2 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 CDJ67642.1 - 1.1e-21 77.2 0.1 2.2e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 PRMT5 TIM barrel domain SUIM_assoc PF16619.5 CDJ67642.1 - 0.0067 16.5 49.1 0.02 14.9 0.7 4.9 4 0 0 4 4 4 3 Unstructured region C-term to UIM in Ataxin3 DUF1645 PF07816.11 CDJ67642.1 - 0.084 13.4 19.8 0.19 12.3 2.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ67642.1 - 1.3 8.6 43.2 1.4 8.5 11.4 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein PepSY_2 PF13670.6 CDJ67644.1 - 0.4 10.7 4.9 0.53 10.3 4.9 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Helicase_C_2 PF13307.6 CDJ67645.1 - 6.6e-10 39.4 0.0 8.5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain TFIIA PF03153.13 CDJ67646.1 - 0.91 9.4 32.5 1.1 9.2 32.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WSC PF01822.19 CDJ67646.1 - 5.7 7.2 34.5 3.5 7.9 6.1 3.2 1 1 2 3 3 3 0 WSC domain MRP-S31 PF15433.6 CDJ67646.1 - 10 5.7 11.3 11 5.5 11.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Pro_isomerase PF00160.21 CDJ67647.1 - 3.8e-48 163.8 0.1 4.2e-48 163.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RPAP1_C PF08620.10 CDJ67648.1 - 1.9e-19 69.5 0.1 8e-19 67.5 0.1 2.2 1 0 0 1 1 1 1 RPAP1-like, C-terminal DUF2722 PF10846.8 CDJ67649.1 - 0.0083 15.1 7.0 0.0079 15.2 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RAP PF08373.10 CDJ67650.1 - 0.00037 20.5 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 RAP domain BHD_3 PF10405.9 CDJ67651.1 - 2.4e-05 24.6 0.0 4.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 CDJ67651.1 - 0.00022 20.9 6.1 0.0014 18.3 0.0 3.6 3 0 0 3 3 3 2 Rad4 transglutaminase-like domain Transglut_core PF01841.19 CDJ67651.1 - 0.006 17.0 0.1 0.08 13.4 0.1 3.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily Pkinase PF00069.25 CDJ67652.1 - 6.5e-35 120.8 1.4 1.5e-34 119.6 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ67652.1 - 1.4e-14 54.0 0.5 6.2e-14 51.9 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 CDJ67652.1 - 0.0083 15.7 0.0 0.0083 15.7 0.0 2.4 3 0 0 3 3 3 1 RIO1 family ATP-synt_D PF01813.17 CDJ67653.1 - 1.7e-57 194.5 2.1 2.1e-57 194.1 2.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit D MIP-T3_C PF17749.1 CDJ67653.1 - 0.027 14.5 0.8 0.027 14.5 0.8 1.6 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region CorA PF01544.18 CDJ67653.1 - 0.076 12.3 0.3 0.12 11.6 0.2 1.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CA_like PF10563.9 CDJ67653.1 - 0.2 11.5 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative carbonic anhydrase APG6_N PF17675.1 CDJ67653.1 - 1.3 9.6 7.5 0.79 10.2 4.9 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Spore_SspJ PF09575.10 CDJ67653.1 - 1.4 9.4 6.2 0.85 10.0 1.3 2.7 3 0 0 3 3 3 0 Small spore protein J (Spore_SspJ) SUIM_assoc PF16619.5 CDJ67654.1 - 1.5 9.0 15.0 0.095 12.8 1.7 2.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DEAD PF00270.29 CDJ67655.1 - 3.8e-42 144.0 0.0 1.2e-41 142.4 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ67655.1 - 2.8e-23 82.4 4.6 2.9e-23 82.3 0.0 3.3 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Pkinase PF00069.25 CDJ67656.1 - 4.9e-36 124.4 0.0 2.7e-23 82.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ67656.1 - 2.6e-23 82.6 0.0 1.2e-17 64.0 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ67656.1 - 0.0006 19.2 0.0 0.0028 17.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ67656.1 - 0.0029 17.0 0.6 0.0029 17.0 0.6 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ67656.1 - 0.04 13.9 0.0 0.04 13.9 0.0 3.6 4 0 0 4 4 4 0 Phosphotransferase enzyme family LSM PF01423.22 CDJ67658.1 - 3.1e-20 71.6 0.1 3.6e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDJ67658.1 - 0.09 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain BRICHOS PF04089.14 CDJ67659.1 - 0.4 10.9 1.1 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 BRICHOS domain DEAD PF00270.29 CDJ67660.1 - 5.3e-36 124.0 0.0 1e-35 123.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ67660.1 - 1.1e-24 87.0 0.0 4e-24 85.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ67660.1 - 1.9e-07 31.3 0.0 4.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CDJ67660.1 - 0.0037 16.9 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 2 SWI2/SNF2 ATPase AP2 PF00847.20 CDJ67661.1 - 2.1e-08 34.2 0.2 1.5e-07 31.5 0.1 2.2 2 0 0 2 2 2 1 AP2 domain HECT PF00632.25 CDJ67664.1 - 2e-92 310.0 0.0 3.5e-92 309.2 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_60s PF00428.19 CDJ67664.1 - 0.0052 17.3 6.6 0.0052 17.3 6.6 7.7 8 1 1 9 9 9 2 60s Acidic ribosomal protein zf-RING_2 PF13639.6 CDJ67665.1 - 0.56 10.6 7.3 1.5 9.3 7.3 1.7 1 1 0 1 1 1 0 Ring finger domain DnaJ PF00226.31 CDJ67666.1 - 1.8e-24 85.6 0.1 1.8e-24 85.6 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain zf-met PF12874.7 CDJ67666.1 - 5e-09 36.2 1.8 2.4e-05 24.6 0.5 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ67666.1 - 9e-09 35.4 1.8 1.3e-05 25.3 0.8 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDJ67666.1 - 1.5e-08 34.9 1.8 0.0062 16.8 0.3 3.6 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CDJ67666.1 - 1.4e-07 31.6 1.9 0.02 15.3 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ67666.1 - 7.4e-06 26.4 2.8 0.13 13.1 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDJ67666.1 - 9.4e-05 22.3 2.0 0.057 13.4 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-MYST PF17772.1 CDJ67666.1 - 0.0068 16.0 1.1 0.011 15.4 0.1 1.8 2 0 0 2 2 2 1 MYST family zinc finger domain zf-DBF PF07535.12 CDJ67666.1 - 0.24 11.5 1.5 0.55 10.4 0.5 2.2 2 0 0 2 2 2 0 DBF zinc finger DUF2757 PF10955.8 CDJ67666.1 - 0.7 10.2 3.2 0.44 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) Kinesin PF00225.23 CDJ67667.1 - 1.7e-69 234.3 0.0 4.5e-69 232.9 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ67667.1 - 5.8e-14 52.3 0.0 2.7e-13 50.1 0.0 2.0 2 1 0 2 2 2 1 Microtubule binding Solute_trans_a PF03619.16 CDJ67668.1 - 1.1e-32 113.6 9.2 1.7e-14 54.0 0.8 3.1 3 0 0 3 3 3 3 Organic solute transporter Ostalpha TPR_1 PF00515.28 CDJ67671.1 - 7.9e-11 41.3 2.2 0.024 14.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ67671.1 - 1.5e-09 37.2 5.9 0.021 14.9 0.3 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ67671.1 - 9.5e-08 32.1 0.9 3.9e-06 26.9 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ67671.1 - 3.2e-07 30.8 6.6 0.0012 19.3 4.9 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ67671.1 - 4.4e-07 29.5 12.8 0.00029 20.5 0.5 3.6 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.6 CDJ67671.1 - 3.4e-06 27.6 8.2 0.0028 18.3 0.8 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ67671.1 - 5.2e-05 23.2 3.2 0.037 14.1 0.2 3.3 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CDJ67671.1 - 7.2e-05 23.3 10.2 0.12 13.3 0.3 4.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ67671.1 - 0.00014 22.3 6.1 3.6 8.4 0.0 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ67671.1 - 0.00059 19.8 2.6 0.23 11.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ67671.1 - 0.00074 19.7 1.9 0.0083 16.3 1.1 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CDJ67671.1 - 0.0008 19.3 0.7 0.58 10.3 0.1 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CDJ67671.1 - 0.004 17.4 2.9 0.004 17.4 2.9 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ67671.1 - 0.0057 16.9 8.1 0.23 11.7 0.2 3.6 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ67671.1 - 0.0094 16.3 1.9 0.098 13.1 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Paf67 PF10255.9 CDJ67671.1 - 0.016 14.2 0.4 0.022 13.8 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 DUF3752 PF12572.8 CDJ67671.1 - 0.33 11.5 10.1 0.71 10.4 10.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) EF-hand_6 PF13405.6 CDJ67672.1 - 0.0014 18.4 0.0 0.004 17.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CDJ67672.1 - 0.0095 15.4 0.0 0.025 14.1 0.0 1.8 1 0 0 1 1 1 1 EF hand ubiquitin PF00240.23 CDJ67672.1 - 0.024 14.4 0.0 7.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin family DWNN PF08783.11 CDJ67672.1 - 0.11 12.7 0.0 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 DWNN domain DAG_kinase_N PF14513.6 CDJ67672.1 - 0.64 10.2 2.6 0.55 10.4 0.4 1.9 1 1 1 2 2 2 0 Diacylglycerol kinase N-terminus ACOX PF01756.19 CDJ67673.1 - 1.2e-37 129.2 1.7 2.2e-37 128.3 1.7 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CDJ67673.1 - 9.8e-16 58.4 0.1 2e-15 57.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CDJ67673.1 - 6.6e-14 51.9 0.0 1.3e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CDJ67673.1 - 0.032 14.4 5.2 0.091 13.0 0.9 3.4 3 1 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain PP2C PF00481.21 CDJ67674.1 - 6.9e-36 124.2 0.0 8.9e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ67674.1 - 7e-06 25.8 0.0 3e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ67674.1 - 2.4e-05 24.4 0.0 0.0059 16.6 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Lactamase_B_2 PF12706.7 CDJ67676.1 - 1.1e-12 47.9 0.0 1.6e-06 27.8 0.0 2.2 1 1 1 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDJ67676.1 - 0.00031 20.7 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain DUF3325 PF11804.8 CDJ67676.1 - 0.31 11.2 6.1 0.84 9.8 6.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) TFIIA PF03153.13 CDJ67676.1 - 3 7.7 7.2 4.1 7.3 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L37e PF01907.19 CDJ67677.1 - 5.9e-26 90.4 12.5 5.9e-26 90.4 12.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L37e SelR PF01641.18 CDJ67677.1 - 0.0035 17.4 1.2 0.0051 16.9 0.8 1.4 1 1 0 1 1 1 1 SelR domain DZR PF12773.7 CDJ67677.1 - 0.041 13.9 1.1 0.061 13.4 1.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF1462 PF07315.11 CDJ67677.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) SR-25 PF10500.9 CDJ67679.1 - 6.3 6.3 49.8 1.1 8.8 16.6 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ67679.1 - 7.5 4.5 49.8 9.2 4.2 49.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Spt20 PF12090.8 CDJ67680.1 - 0.72 9.4 33.3 0.064 12.9 25.1 2.1 2 0 0 2 2 2 0 Spt20 family SPX PF03105.19 CDJ67680.1 - 0.87 9.4 18.0 1.1 9.0 18.0 1.1 1 0 0 1 1 1 0 SPX domain SpoIIP PF07454.11 CDJ67680.1 - 8.7 5.7 10.9 1.1 8.7 3.9 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Elf1 PF05129.13 CDJ67681.1 - 1.3e-21 76.5 0.3 2.5e-21 75.5 0.3 1.5 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DUF4179 PF13786.6 CDJ67681.1 - 0.026 15.0 11.3 1.1 9.8 3.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) RIFIN PF02009.16 CDJ67681.1 - 0.62 9.9 12.9 0.86 9.4 12.9 1.3 1 0 0 1 1 1 0 Rifin SWIRM-assoc_2 PF16496.5 CDJ67681.1 - 0.89 8.4 7.4 1 8.2 7.4 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal TP53IP5 PF15331.6 CDJ67681.1 - 1.2 9.2 11.3 1.7 8.7 11.3 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 LAP1C PF05609.12 CDJ67681.1 - 1.2 8.1 19.0 1.6 7.8 19.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4813 PF16072.5 CDJ67681.1 - 1.3 8.6 33.6 0.19 11.3 10.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) Dehydrin PF00257.19 CDJ67681.1 - 5.8 7.4 31.8 0.028 15.0 12.8 2.2 1 1 1 2 2 2 0 Dehydrin GREB1 PF15782.5 CDJ67681.1 - 8.6 3.3 10.0 9.4 3.2 10.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 CDJ67681.1 - 8.9 4.8 8.8 10 4.6 8.8 1.1 1 0 0 1 1 1 0 Hamartin protein Zip PF02535.22 CDJ67681.1 - 9.4 5.3 5.7 13 4.9 5.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter HIT PF01230.23 CDJ67682.1 - 4.5e-11 43.3 0.0 1e-09 39.0 0.0 2.0 2 0 0 2 2 2 1 HIT domain SR-25 PF10500.9 CDJ67683.1 - 0.0067 16.1 12.4 0.0067 16.1 12.4 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 CDJ67683.1 - 0.026 14.2 4.7 0.066 12.9 4.7 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF572 PF04502.13 CDJ67683.1 - 0.42 10.2 5.5 0.5 9.9 5.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOG2 PF10428.9 CDJ67683.1 - 4 6.5 14.7 4.5 6.4 14.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein TOM13 PF08219.11 CDJ67684.1 - 0.53 10.3 0.0 0.53 10.3 0.0 4.9 7 0 0 7 7 7 0 Outer membrane protein TOM13 NTP_transferase PF00483.23 CDJ67685.1 - 1.4e-13 51.0 0.0 1.4e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CDJ67685.1 - 3.5e-08 34.0 0.0 3.7e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain LAMTOR PF15454.6 CDJ67686.1 - 0.011 16.3 5.1 0.011 16.3 5.1 2.2 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator JHY PF15261.6 CDJ67686.1 - 0.045 14.5 14.6 0.055 14.2 14.6 1.2 1 0 0 1 1 1 0 Jhy protein Trp_oprn_chp PF09534.10 CDJ67686.1 - 0.4 10.4 17.4 0.58 9.9 17.4 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4484 PF14831.6 CDJ67686.1 - 0.45 10.5 8.2 0.51 10.3 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF4569 PF15133.6 CDJ67686.1 - 1 9.0 10.1 1.2 8.7 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF5421 PF17458.2 CDJ67686.1 - 1.6 8.0 13.3 1.7 8.0 1.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5421) CNDH2_M PF16869.5 CDJ67686.1 - 1.8 9.2 10.7 2.3 8.9 10.7 1.2 1 0 0 1 1 1 0 PF16858 FAM60A PF15396.6 CDJ67686.1 - 2.2 8.2 6.2 2.7 7.9 6.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Med19 PF10278.9 CDJ67686.1 - 2.7 7.9 7.0 1.5 8.7 0.7 2.0 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 SLC12 PF03522.15 CDJ67686.1 - 4.8 6.1 8.4 5.2 6.0 8.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SAGA-Tad1 PF12767.7 CDJ67686.1 - 4.9 6.8 11.1 7.3 6.3 11.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Presenilin PF01080.17 CDJ67686.1 - 7.2 5.3 14.9 8.4 5.0 14.9 1.0 1 0 0 1 1 1 0 Presenilin DUF4638 PF15472.6 CDJ67686.1 - 7.7 6.2 8.7 9.4 5.9 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) WTX PF09422.10 CDJ67686.1 - 10 5.1 15.4 11 4.9 15.4 1.0 1 0 0 1 1 1 0 WTX protein Hexapep PF00132.24 CDJ67687.1 - 2.7e-09 36.4 2.9 8.8e-07 28.4 0.2 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CDJ67687.1 - 0.0052 16.5 0.6 0.022 14.5 0.1 2.3 2 1 1 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CDJ67687.1 - 0.13 10.4 0.0 0.18 9.9 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 CDJ67687.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.3 1 1 0 1 1 1 0 L-fucokinase SUIM_assoc PF16619.5 CDJ67688.1 - 0.039 14.0 0.5 0.039 14.0 0.5 3.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2057 PF09829.9 CDJ67688.1 - 3.6 7.7 54.5 0.28 11.3 4.3 5.2 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2057) AF-4 PF05110.13 CDJ67688.1 - 5.1 5.0 10.4 0.75 7.8 5.4 1.9 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Prenyltransf PF01255.19 CDJ67689.1 - 1.8e-46 158.4 0.0 1.4e-45 155.6 0.0 1.9 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Gastrin PF00918.17 CDJ67689.1 - 0.079 13.9 3.5 0.18 12.7 3.5 1.6 1 0 0 1 1 1 0 Gastrin/cholecystokinin family FPN1 PF06963.12 CDJ67689.1 - 0.43 9.1 2.1 0.34 9.4 0.6 1.5 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Spt20 PF12090.8 CDJ67689.1 - 1.1 8.8 19.8 0.05 13.2 8.0 2.2 2 0 0 2 2 2 0 Spt20 family FAP PF07174.11 CDJ67689.1 - 3.8 6.9 15.3 3.6 6.9 12.5 1.9 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) TraT PF05818.12 CDJ67690.1 - 0.0034 17.1 11.9 0.0034 17.1 11.9 4.5 3 3 1 4 4 4 1 Enterobacterial TraT complement resistance protein Pex14_N PF04695.13 CDJ67690.1 - 0.02 15.6 16.1 0.02 15.6 16.1 4.2 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EPL1 PF10513.9 CDJ67690.1 - 0.034 14.6 0.5 0.034 14.6 0.5 2.9 2 1 1 3 3 3 0 Enhancer of polycomb-like Connexin PF00029.19 CDJ67690.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.6 2 1 0 2 2 2 0 Connexin SOBP PF15279.6 CDJ67690.1 - 0.49 11.0 31.1 1.4 9.5 0.8 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein RNase_H2_suC PF08615.11 CDJ67690.1 - 1.8 8.7 15.0 2.5 8.3 0.0 2.9 2 1 1 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Hamartin PF04388.12 CDJ67690.1 - 5.9 5.4 31.7 2.3 6.8 2.1 2.1 2 0 0 2 2 2 0 Hamartin protein rve PF00665.26 CDJ67691.1 - 5.4e-16 58.9 0.0 9e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ67691.1 - 4.7e-12 45.6 0.0 9.7e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 CDJ67691.1 - 1.4e-11 44.3 2.7 4.4e-11 42.7 2.7 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ67691.1 - 0.075 13.3 0.3 0.18 12.0 0.3 1.6 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 CDJ67691.1 - 0.08 12.7 0.7 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 Integrase core domain TMEM154 PF15102.6 CDJ67693.1 - 0.11 12.4 0.2 0.75 9.7 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family PALP PF00291.25 CDJ67694.1 - 1.6e-48 165.6 0.0 2.4e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HECT PF00632.25 CDJ67695.1 - 7.1e-83 278.6 0.0 1e-82 278.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WSD PF15613.6 CDJ67696.1 - 0.0003 21.2 0.0 0.0003 21.2 0.0 6.0 4 3 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Auxin_resp PF06507.13 CDJ67696.1 - 0.00057 20.1 0.0 0.0019 18.4 0.0 1.8 2 0 0 2 2 2 1 Auxin response factor DDT PF02791.17 CDJ67696.1 - 0.13 12.6 0.1 0.5 10.7 0.1 1.9 1 0 0 1 1 1 0 DDT domain Sec63 PF02889.16 CDJ67697.1 - 1.6e-09 37.4 0.1 3.8e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Sec63 Brl domain DUF2722 PF10846.8 CDJ67697.1 - 0.00036 19.6 2.5 0.00036 19.6 2.5 2.9 2 1 0 2 2 1 1 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ67697.1 - 0.00077 19.5 1.1 0.00077 19.5 1.1 4.6 4 1 0 4 4 2 1 Unstructured region C-term to UIM in Ataxin3 CPSF100_C PF13299.6 CDJ67697.1 - 0.013 15.7 2.8 1.5 9.0 0.2 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 CDJ67697.1 - 0.031 14.3 31.2 0.54 10.2 10.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CDJ67697.1 - 0.083 11.6 5.1 0.38 9.4 0.2 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup ORC3_N PF07034.11 CDJ67697.1 - 0.089 11.9 6.0 0.11 11.6 1.0 2.6 3 0 0 3 3 3 0 Origin recognition complex (ORC) subunit 3 N-terminus EPL1 PF10513.9 CDJ67697.1 - 0.11 12.9 9.0 2.4 8.5 0.5 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like eIF-3_zeta PF05091.12 CDJ67697.1 - 0.16 10.9 12.4 0.4 9.6 1.7 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rsm1 PF08600.10 CDJ67697.1 - 0.33 11.1 4.7 0.52 10.5 0.6 2.6 2 0 0 2 2 2 0 Rsm1-like DFRP_C PF16543.5 CDJ67697.1 - 0.56 10.7 11.0 0.29 11.6 0.9 2.3 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 DUF4050 PF13259.6 CDJ67697.1 - 0.64 10.3 8.6 3.2 8.0 8.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) DNApol_Exo PF18136.1 CDJ67697.1 - 1.1 8.3 5.6 3.5 6.7 1.4 2.1 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain DUF4407 PF14362.6 CDJ67697.1 - 1.2 8.4 11.6 0.61 9.4 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CobT PF06213.12 CDJ67697.1 - 2.2 7.6 17.2 2.5 7.4 3.1 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT YABBY PF04690.13 CDJ67697.1 - 2.4 8.7 4.9 9.3 6.8 0.3 2.2 2 0 0 2 2 2 0 YABBY protein SARAF PF06682.12 CDJ67697.1 - 2.6 7.6 10.7 0.92 9.1 0.5 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Hep_59 PF07052.11 CDJ67697.1 - 3.2 8.6 13.4 8.4 7.2 4.4 2.4 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 DUF4770 PF15994.5 CDJ67697.1 - 3.8 7.7 16.0 5.6 7.2 2.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4770) LytR_cpsA_psr PF03816.14 CDJ67697.1 - 4 7.6 8.6 6.5 6.9 0.1 2.3 2 0 0 2 2 2 0 Cell envelope-related transcriptional attenuator domain U3_snoRNA_assoc PF08297.11 CDJ67697.1 - 4.6 8.0 10.0 1.1 10.0 1.4 2.4 2 0 0 2 2 2 0 U3 snoRNA associated Peptidase_U57 PF05582.12 CDJ67697.1 - 4.8 6.4 6.1 0.65 9.2 0.3 2.0 2 0 0 2 2 2 0 YabG peptidase U57 P16-Arc PF04699.14 CDJ67697.1 - 7 7.1 10.5 5.6 7.4 0.4 2.3 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Band_3_cyto PF07565.13 CDJ67697.1 - 7.5 6.3 9.7 11 5.7 0.7 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain preATP-grasp_3 PF18301.1 CDJ67698.1 - 0.067 13.5 0.0 0.39 11.0 0.0 2.1 1 1 1 2 2 2 0 pre ATP-grasp 3 domain RLI PF04068.15 CDJ67699.1 - 7.2e-07 28.9 0.1 1.6e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Ribo_biogen_C PF04034.13 CDJ67699.1 - 0.089 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein, C-terminal SR-25 PF10500.9 CDJ67699.1 - 4.8 6.7 19.9 1 9.0 8.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein gpUL132 PF11359.8 CDJ67700.1 - 0.13 11.8 0.2 1.4 8.4 0.2 2.1 2 0 0 2 2 2 0 Glycoprotein UL132 BLOC1_2 PF10046.9 CDJ67701.1 - 0.86 9.9 8.4 2.6 8.4 0.7 3.6 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAA_hydro_N_2 PF18288.1 CDJ67701.1 - 4.7 7.7 7.9 19 5.8 0.1 4.2 4 0 0 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 SET PF00856.28 CDJ67702.1 - 4e-09 37.1 0.6 4e-08 33.8 0.1 2.2 1 1 0 2 2 2 1 SET domain Nitroreductase PF00881.24 CDJ67702.1 - 0.023 14.8 0.4 7.6 6.6 0.0 3.0 1 1 2 3 3 3 0 Nitroreductase family CTNNBL PF08216.11 CDJ67702.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear TBCC PF07986.12 CDJ67704.1 - 0.028 14.2 0.1 0.086 12.6 0.1 1.8 1 1 0 1 1 1 0 Tubulin binding cofactor C SMC_N PF02463.19 CDJ67705.1 - 2.3e-51 174.3 0.0 4.3e-51 173.4 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDJ67705.1 - 2.9e-13 50.2 0.0 2.4e-12 47.2 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CDJ67705.1 - 5.3e-09 36.3 8.3 0.00022 21.1 0.3 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDJ67705.1 - 1.9e-07 31.1 3.0 1.9e-07 31.1 3.0 4.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 CDJ67705.1 - 4.6e-05 24.0 30.8 4.6e-05 24.0 30.8 7.1 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 CDJ67705.1 - 0.00037 20.2 0.0 0.00084 19.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6_N PF17675.1 CDJ67705.1 - 0.00067 20.2 17.9 0.00067 20.2 17.9 8.7 3 3 4 8 8 8 2 Apg6 coiled-coil region ABC_tran PF00005.27 CDJ67705.1 - 0.0011 19.5 0.4 0.0031 18.0 0.3 6.4 4 2 2 6 6 6 2 ABC transporter DUF1409 PF07197.12 CDJ67705.1 - 0.025 14.4 0.2 0.24 11.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) CCSAP PF15748.5 CDJ67706.1 - 0.098 12.8 14.0 0.11 12.7 14.0 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TFIIA PF03153.13 CDJ67706.1 - 0.37 10.7 29.3 0.46 10.4 29.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ67706.1 - 0.38 9.4 35.3 0.42 9.2 35.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4757 PF15949.5 CDJ67706.1 - 0.63 10.5 14.4 0.84 10.1 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) RR_TM4-6 PF06459.12 CDJ67706.1 - 0.85 9.4 10.9 0.96 9.2 10.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 CDJ67706.1 - 3.2 6.9 6.4 3.3 6.8 6.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter WBP-1 PF11669.8 CDJ67706.1 - 3.7 8.2 10.6 0.9 10.2 1.2 2.2 2 0 0 2 2 2 0 WW domain-binding protein 1 Presenilin PF01080.17 CDJ67706.1 - 4.8 5.8 16.8 5.8 5.6 16.8 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ67706.1 - 5 7.1 8.9 6.8 6.7 8.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Metallophos PF00149.28 CDJ67707.1 - 2.5e-25 90.2 0.0 3.2e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase INTS5_N PF14837.6 CDJ67709.1 - 0.031 13.9 1.1 0.054 13.1 1.1 1.3 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Presenilin PF01080.17 CDJ67709.1 - 0.56 8.9 3.9 1.1 7.9 3.9 1.4 1 0 0 1 1 1 0 Presenilin Xpo1 PF08389.12 CDJ67709.1 - 4 7.5 9.5 0.19 11.7 2.1 2.1 1 1 1 2 2 2 0 Exportin 1-like protein Peptidase_C50 PF03568.17 CDJ67710.1 - 1.2e-11 44.4 0.1 1.2e-11 44.4 0.1 6.8 7 0 0 7 7 7 2 Peptidase family C50 RskA PF10099.9 CDJ67710.1 - 0.00066 20.0 0.1 0.00066 20.0 0.1 34.8 8 6 19 30 30 30 3 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ67710.1 - 0.62 10.2 0.0 0.61 10.2 1.7 36.3 32 6 2 34 34 34 0 Unstructured region C-term to UIM in Ataxin3 ADK PF00406.22 CDJ67711.1 - 8.6e-29 100.6 0.0 4.2e-22 78.9 0.0 2.6 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CDJ67711.1 - 2.1e-22 80.0 6.8 8.9e-17 61.8 0.0 3.8 4 0 0 4 4 4 2 AAA domain Rad9 PF04139.13 CDJ67711.1 - 1.2e-05 24.9 0.0 0.018 14.5 0.0 2.4 2 0 0 2 2 2 2 Rad9 AAA_18 PF13238.6 CDJ67711.1 - 0.00068 20.2 1.5 1.8 9.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain SR-25 PF10500.9 CDJ67711.1 - 0.0012 18.5 4.4 0.0012 18.5 4.4 4.6 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ67711.1 - 0.0097 16.2 0.1 0.0097 16.2 0.1 10.5 5 1 2 7 7 7 3 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ67711.1 - 0.014 16.4 0.2 0.014 16.4 0.2 6.5 6 1 1 7 7 7 0 Domain of unknown function (DUF4834) DUF4667 PF15700.5 CDJ67711.1 - 0.014 15.5 25.8 0.66 10.0 7.2 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4667) KASH PF10541.9 CDJ67711.1 - 1.4 9.2 8.4 4.9 7.5 8.4 1.9 1 0 0 1 1 1 0 Nuclear envelope localisation domain GSG-1 PF07803.11 CDJ67711.1 - 1.5 8.7 6.5 0.14 12.1 0.7 2.3 2 0 0 2 2 2 0 GSG1-like protein RskA PF10099.9 CDJ67712.1 - 0.9 9.8 22.9 0.24 11.7 7.4 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA CDC45 PF02724.14 CDJ67712.1 - 6.5 4.9 15.7 6.9 4.8 15.7 1.0 1 0 0 1 1 1 0 CDC45-like protein RAB3GAP2_N PF14655.6 CDJ67714.1 - 0.0084 15.4 3.9 0.0084 15.4 3.9 1.6 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus SPX PF03105.19 CDJ67714.1 - 0.014 15.3 28.0 0.055 13.4 11.3 2.1 1 1 1 2 2 2 0 SPX domain RskA PF10099.9 CDJ67714.1 - 4.5 7.5 17.7 0.98 9.7 11.8 2.2 1 1 0 2 2 2 0 Anti-sigma-K factor rskA Eapp_C PF10238.9 CDJ67715.1 - 5.3e-12 46.0 1.3 5.3e-12 46.0 1.3 2.5 3 0 0 3 3 3 1 E2F-associated phosphoprotein SR-25 PF10500.9 CDJ67715.1 - 0.0048 16.5 40.4 0.018 14.6 11.5 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 CDJ67715.1 - 0.22 12.1 29.6 1.4 9.5 5.4 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain DUF3498 PF12004.8 CDJ67715.1 - 1.3 8.2 23.1 1.6 7.8 23.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Utp14 PF04615.13 CDJ67715.1 - 1.6 7.2 3.7 1.9 7.0 3.7 1.1 1 0 0 1 1 1 0 Utp14 protein SOG2 PF10428.9 CDJ67715.1 - 1.9 7.6 22.8 2.3 7.3 22.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RSRP PF17069.5 CDJ67715.1 - 1.9 8.0 39.4 1 8.9 17.5 2.2 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 CCDC106 PF15794.5 CDJ67715.1 - 3.8 7.2 16.5 5.3 6.7 1.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DA1-like PF12315.8 CDJ67715.1 - 5.1 6.4 6.6 2.1 7.7 1.1 2.2 2 0 0 2 2 2 0 Protein DA1 TFIIA PF03153.13 CDJ67716.1 - 0.016 15.3 42.0 0.021 14.8 42.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Abhydrolase_9_N PF15420.6 CDJ67716.1 - 0.45 10.5 6.7 2.4 8.1 0.3 2.6 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Hamartin PF04388.12 CDJ67716.1 - 2.6 6.6 12.3 2.8 6.5 12.3 1.1 1 0 0 1 1 1 0 Hamartin protein GREB1 PF15782.5 CDJ67716.1 - 3.1 4.8 16.1 3.1 4.8 16.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SID-1_RNA_chan PF13965.6 CDJ67716.1 - 3.6 5.9 4.0 4.4 5.6 4.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 CDJ67716.1 - 8.9 4.4 31.8 11 4.2 31.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1980 PF09323.10 CDJ67716.1 - 9.5 6.1 8.9 21 5.0 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Ribosomal_S6e PF01092.19 CDJ67717.1 - 6.7e-53 177.9 0.0 8.2e-53 177.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6e TFIIA PF03153.13 CDJ67718.1 - 0.0034 17.5 13.5 0.0037 17.3 13.5 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ67718.1 - 0.0059 15.6 9.8 0.0066 15.4 9.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ67718.1 - 0.0077 15.9 15.0 0.0095 15.6 15.0 1.1 1 0 0 1 1 1 1 Spt20 family RAB3GAP2_N PF14655.6 CDJ67718.1 - 0.039 13.2 1.2 0.05 12.9 1.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4834 PF16118.5 CDJ67718.1 - 0.46 11.5 5.2 0.74 10.8 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ67718.1 - 0.6 10.0 3.4 0.66 9.9 3.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RskA PF10099.9 CDJ67718.1 - 1.2 9.3 20.8 1.1 9.5 20.0 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Med15 PF09606.10 CDJ67718.1 - 1.4 7.6 22.2 1.6 7.4 22.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1180 PF06679.12 CDJ67718.1 - 1.7 9.0 5.1 2.9 8.3 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) UPF0560 PF10577.9 CDJ67718.1 - 2.4 6.6 6.5 2.7 6.4 6.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1840 PF08895.11 CDJ67718.1 - 6.6 7.1 7.9 0.62 10.4 3.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) DUF1645 PF07816.11 CDJ67719.1 - 0.016 15.8 0.8 0.016 15.8 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) Connexin PF00029.19 CDJ67719.1 - 0.14 11.9 2.1 0.23 11.2 2.1 1.3 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ67719.1 - 0.43 9.3 13.3 1.8 7.3 13.2 1.9 2 0 0 2 2 2 0 Presenilin NPR3 PF03666.13 CDJ67719.1 - 0.46 9.2 8.1 0.92 8.2 8.1 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.16 CDJ67719.1 - 0.49 10.4 6.2 1.3 9.1 6.2 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 CDJ67719.1 - 2.4 7.1 16.3 3.7 6.4 16.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Baculo_PP31 PF05311.11 CDJ67719.1 - 4.1 6.8 7.6 7.4 6.0 7.6 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Cellulose_synt PF03552.14 CDJ67720.1 - 2.5 6.5 10.7 3.8 5.9 10.7 1.2 1 0 0 1 1 1 0 Cellulose synthase HEAT PF02985.22 CDJ67720.1 - 4.6 7.8 5.9 6.8 7.2 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Asp-B-Hydro_N PF05279.11 CDJ67720.1 - 7.9 6.5 31.6 28 4.7 31.6 1.9 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TFIIA PF03153.13 CDJ67722.1 - 0.21 11.5 23.6 0.24 11.3 23.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3533 PF12051.8 CDJ67722.1 - 1 8.2 3.9 0.79 8.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) Presenilin PF01080.17 CDJ67722.1 - 6.4 5.4 8.1 7.7 5.2 8.1 1.1 1 0 0 1 1 1 0 Presenilin Surface_antigen PF11054.8 CDJ67723.1 - 1.4e-57 195.2 5.1 2e-57 194.7 5.1 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF3138 PF11336.8 CDJ67724.1 - 3.5 6.1 11.3 3.7 6.1 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) WD40 PF00400.32 CDJ67726.1 - 2.2e-07 31.4 12.8 0.0035 18.1 0.5 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF2722 PF10846.8 CDJ67726.1 - 0.0055 15.7 1.7 0.0055 15.7 1.7 3.9 3 1 1 4 4 4 2 Protein of unknown function (DUF2722) ANAPC4_WD40 PF12894.7 CDJ67726.1 - 0.011 16.0 0.0 37 4.7 0.0 4.6 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Syntaxin PF00804.25 CDJ67728.1 - 4.8e-07 29.6 0.9 6e-07 29.3 0.9 1.1 1 0 0 1 1 1 1 Syntaxin Dymeclin PF09742.9 CDJ67728.1 - 0.023 13.1 2.1 0.083 11.3 0.1 2.0 1 1 1 2 2 2 0 Dyggve-Melchior-Clausen syndrome protein DUF1204 PF06721.11 CDJ67728.1 - 0.034 13.6 1.4 0.048 13.1 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Hid1 PF12722.7 CDJ67728.1 - 0.04 12.1 0.0 0.25 9.4 0.0 2.0 1 1 1 2 2 2 0 High-temperature-induced dauer-formation protein Pox_EPC_I2-L1 PF12575.8 CDJ67728.1 - 0.057 13.7 0.1 0.095 12.9 0.1 1.4 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 TAF PF02969.17 CDJ67728.1 - 0.13 12.5 0.9 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Het-C PF07217.11 CDJ67729.1 - 9.3 4.7 11.2 20 3.5 11.2 1.5 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Bacteriocin_IIc PF10439.9 CDJ67730.1 - 0.072 13.2 6.1 0.21 11.7 6.1 1.8 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Hamartin PF04388.12 CDJ67730.1 - 0.95 8.1 10.3 1.1 7.8 10.3 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4407 PF14362.6 CDJ67730.1 - 1.9 7.8 23.3 2.8 7.2 23.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) His_Phos_1 PF00300.22 CDJ67731.1 - 1.7e-17 63.8 0.7 2.1e-17 63.4 0.3 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_60s PF00428.19 CDJ67731.1 - 0.0024 18.4 8.5 0.0038 17.8 8.5 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Hamartin PF04388.12 CDJ67732.1 - 0.53 8.9 29.9 0.7 8.5 29.9 1.1 1 0 0 1 1 1 0 Hamartin protein GPHR_N PF12537.8 CDJ67732.1 - 0.54 10.4 0.0 0.54 10.4 0.0 2.6 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal ArsP_2 PF11449.8 CDJ67732.1 - 2.7 7.1 7.4 4.7 6.3 7.4 1.3 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter Rod-binding PF10135.9 CDJ67733.1 - 0.061 13.9 0.2 0.17 12.4 0.2 1.8 1 1 1 2 2 2 0 Rod binding protein Fam20C PF06702.12 CDJ67733.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 DOT1 PF08123.13 CDJ67734.1 - 0.00023 20.8 0.0 0.00056 19.5 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.13 CDJ67734.1 - 0.0022 17.4 2.1 0.0036 16.8 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) DUF2714 PF10896.8 CDJ67734.1 - 0.044 13.8 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2714) Guanylate_cyc PF00211.20 CDJ67735.1 - 2.1e-70 236.1 0.2 5.5e-35 120.6 2.2 3.6 2 2 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Hydrolase PF00702.26 CDJ67735.1 - 0.00019 21.8 0.2 0.014 15.7 0.0 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ67735.1 - 0.0023 17.5 0.0 0.17 11.4 0.0 3.0 2 0 0 2 2 2 1 E1-E2 ATPase RPA43_OB PF17875.1 CDJ67736.1 - 0.15 12.7 0.7 2.2 8.9 0.0 2.7 2 1 1 3 3 3 0 RPA43 OB domain in RNA Pol I ARID PF01388.21 CDJ67737.1 - 7e-13 49.1 2.4 1e-12 48.6 0.0 2.7 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Transket_pyr PF02779.24 CDJ67738.1 - 2e-58 197.0 0.1 7.7e-58 195.1 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CDJ67738.1 - 3.5e-53 180.5 0.8 5.4e-53 179.9 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CDJ67738.1 - 5.9e-48 162.4 0.0 4.9e-46 156.2 0.0 2.6 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CDJ67738.1 - 5.8e-14 51.4 0.1 1.1e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus RAWUL PF16207.5 CDJ67738.1 - 0.06 14.0 1.9 0.18 12.5 1.9 1.8 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like LRR_6 PF13516.6 CDJ67739.1 - 0.00085 19.2 3.8 0.0027 17.6 0.6 3.0 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.7 CDJ67739.1 - 0.0024 18.2 1.4 0.76 10.3 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) DUF992 PF06186.11 CDJ67739.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF992) Pyridoxal_deC PF00282.19 CDJ67739.1 - 3.9 6.1 5.1 12 4.5 0.2 2.1 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain DivIC PF04977.15 CDJ67740.1 - 4.8 7.0 7.4 3.9 7.3 1.6 2.7 2 0 0 2 2 2 0 Septum formation initiator LMBR1 PF04791.16 CDJ67741.1 - 0.0046 15.9 0.8 0.12 11.2 0.2 2.2 2 1 0 2 2 2 2 LMBR1-like membrane protein HxlR PF01638.17 CDJ67741.1 - 0.03 14.2 1.2 0.059 13.2 0.1 2.1 2 0 0 2 2 2 0 HxlR-like helix-turn-helix FlaC_arch PF05377.11 CDJ67741.1 - 2.3 8.7 8.4 0.55 10.7 1.1 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Adeno_PIX PF03955.14 CDJ67742.1 - 0.83 9.9 17.1 0.34 11.1 4.4 2.7 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Presenilin PF01080.17 CDJ67742.1 - 1.9 7.2 3.5 3 6.5 3.5 1.3 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ67742.1 - 3.1 8.4 12.6 0.052 14.2 3.9 2.3 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LMF1 PF06762.14 CDJ67745.1 - 4.8e-51 174.3 3.6 8.7e-51 173.4 3.6 1.3 1 0 0 1 1 1 1 Lipase maturation factor XPG_I PF00867.18 CDJ67746.1 - 2e-20 73.0 0.1 8.5e-20 70.9 0.1 2.2 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 CDJ67746.1 - 0.004 16.7 0.3 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 XPG domain containing EFF-AFF PF14884.6 CDJ67746.1 - 0.028 12.5 0.0 0.043 12.0 0.0 1.2 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen TSP_1 PF00090.19 CDJ67747.1 - 3.6e-99 324.8 238.7 1e-11 44.9 4.4 20.8 19 1 0 19 19 19 16 Thrombospondin type 1 domain Notch PF00066.17 CDJ67747.1 - 6.6e-25 87.3 92.3 2e-07 31.3 14.0 8.8 6 0 0 6 6 6 4 LNR domain DUF4328 PF14219.6 CDJ67747.1 - 0.12 11.9 0.7 0.23 11.0 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) RIBIOP_C PF04950.12 CDJ67748.1 - 4.6e-83 279.0 0.0 3.6e-82 276.1 0.0 2.1 1 1 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CDJ67748.1 - 6.6e-08 32.5 0.0 2.1e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CCDC66 PF15236.6 CDJ67749.1 - 0.00025 20.9 13.6 0.00025 20.9 13.6 3.0 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 66 Colicin-DNase PF12639.7 CDJ67749.1 - 7.1 7.5 7.0 0.93 10.4 0.1 2.8 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin SbcD_C PF12320.8 CDJ67751.1 - 0.07 13.4 0.2 2 8.8 0.1 2.6 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Tae4 PF14113.6 CDJ67751.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 GST_C_6 PF17171.4 CDJ67752.1 - 2.2e-12 46.6 0.1 4.7e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CDJ67752.1 - 1.7e-06 28.3 0.0 4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 CDJ67752.1 - 0.0088 16.0 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EGF_CA PF07645.15 CDJ67753.1 - 3.7e-16 59.1 22.4 1.5e-08 34.7 6.7 4.1 3 0 0 3 3 3 3 Calcium-binding EGF domain cEGF PF12662.7 CDJ67753.1 - 1.1e-10 41.3 21.6 3.1e-06 27.0 5.7 4.0 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CDJ67753.1 - 9.4e-10 38.5 23.0 0.001 19.2 7.5 4.0 3 0 0 3 3 3 3 EGF domain Peptidase_C11 PF03415.14 CDJ67753.1 - 1.4e-06 28.0 0.0 0.00013 21.6 0.0 2.9 3 0 0 3 3 3 1 Clostripain family Notch PF00066.17 CDJ67753.1 - 6.9e-06 26.4 2.3 6.9e-06 26.4 2.3 2.5 3 0 0 3 3 3 1 LNR domain FXa_inhibition PF14670.6 CDJ67753.1 - 0.003 17.8 7.7 0.003 17.8 7.7 4.0 4 0 0 4 4 4 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 CDJ67753.1 - 0.006 16.9 2.8 0.006 16.9 2.8 5.0 6 0 0 6 6 6 2 EGF-like domain EGF_MSP1_1 PF12946.7 CDJ67753.1 - 0.017 15.1 11.5 0.58 10.3 2.1 3.4 3 0 0 3 3 3 0 MSP1 EGF domain 1 Herpes_gE PF02480.16 CDJ67754.1 - 0.0029 16.4 0.1 0.0045 15.8 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Nop14 PF04147.12 CDJ67754.1 - 0.015 13.5 2.5 0.021 13.1 2.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4054 PF13262.6 CDJ67754.1 - 0.046 13.7 0.5 0.046 13.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) RskA PF10099.9 CDJ67754.1 - 0.051 13.9 17.7 0.093 13.0 0.3 3.3 3 1 0 3 3 3 0 Anti-sigma-K factor rskA DNA_pol_phi PF04931.13 CDJ67754.1 - 0.26 9.3 10.1 0.38 8.8 10.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4179 PF13786.6 CDJ67754.1 - 0.52 10.8 6.2 15 6.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) CBM_20 PF00686.19 CDJ67755.1 - 1.1e-14 54.1 0.0 3.4e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Starch binding domain PAP1 PF08601.10 CDJ67755.1 - 0.0014 18.5 19.8 0.0014 18.5 19.8 4.6 4 1 0 4 4 4 1 Transcription factor PAP1 Zip PF02535.22 CDJ67755.1 - 0.4 9.8 9.6 0.045 13.0 1.7 2.8 3 0 0 3 3 3 0 ZIP Zinc transporter RskA PF10099.9 CDJ67756.1 - 0.004 17.5 0.8 0.004 17.5 0.8 17.7 5 3 9 14 14 14 3 Anti-sigma-K factor rskA TetR_C_37 PF18665.1 CDJ67756.1 - 7.6 7.2 7.7 1.7 9.3 2.1 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Pex14_N PF04695.13 CDJ67757.1 - 0.15 12.7 15.8 0.16 12.6 15.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WBP-1 PF11669.8 CDJ67757.1 - 1 10.0 2.9 1.5 9.5 2.9 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 Lin-8 PF03353.15 CDJ67757.1 - 2.1 7.9 7.8 2.4 7.6 7.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ67757.1 - 2.1 7.9 15.1 2.7 7.5 15.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Virul_Fac PF10139.9 CDJ67757.1 - 2.7 6.1 4.9 3.2 5.9 4.9 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor NUDE_C PF04880.13 CDJ67757.1 - 6.9 7.1 15.2 8.3 6.9 15.2 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region SUIM_assoc PF16619.5 CDJ67758.1 - 5.5e-05 23.2 40.0 0.002 18.2 1.6 3.9 3 0 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 DUF572 PF04502.13 CDJ67758.1 - 0.033 13.8 5.7 0.38 10.3 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) ANAPC_CDC26 PF10471.9 CDJ67758.1 - 0.49 11.3 46.1 0.13 13.1 8.9 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Ribosomal_60s PF00428.19 CDJ67759.1 - 5.2 7.7 12.7 0.14 12.7 3.7 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein RRM_1 PF00076.22 CDJ67760.1 - 1.8e-16 59.7 0.0 2.9e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ67760.1 - 0.0041 17.2 0.0 0.0069 16.5 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CDJ67760.1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CDJ67760.1 - 0.1 12.8 0.1 0.26 11.5 0.1 1.6 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DnaJ PF00226.31 CDJ67761.1 - 6.5e-13 48.6 0.8 1.6e-12 47.3 0.8 1.6 1 1 0 1 1 1 1 DnaJ domain PI3_PI4_kinase PF00454.27 CDJ67762.1 - 1.3e-21 77.6 0.2 1.8e-21 77.1 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Acetyltransf_1 PF00583.25 CDJ67762.1 - 5.7e-05 23.3 0.1 0.00012 22.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ67762.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SR-25 PF10500.9 CDJ67762.1 - 0.087 12.4 15.8 0.19 11.3 15.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4135 PF13575.6 CDJ67762.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Herpes_pp85 PF04637.12 CDJ67762.1 - 0.27 9.6 6.0 0.49 8.7 6.0 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) AF-4 PF05110.13 CDJ67762.1 - 2.6 6.0 15.2 3.6 5.5 15.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IMP2_N PF18590.1 CDJ67763.1 - 9.4e-17 61.4 0.4 9.4e-17 61.4 0.4 1.7 2 0 0 2 2 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain TFIIA PF03153.13 CDJ67763.1 - 0.00045 20.3 24.0 0.00052 20.1 24.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SAGA-Tad1 PF12767.7 CDJ67763.1 - 0.004 16.9 6.9 0.0049 16.6 6.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit CDC45 PF02724.14 CDJ67763.1 - 0.0066 14.8 6.3 0.0068 14.8 6.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Lin-8 PF03353.15 CDJ67763.1 - 0.077 12.5 14.4 0.079 12.5 14.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PTPRCAP PF15713.5 CDJ67763.1 - 0.26 11.5 12.9 0.41 10.9 12.9 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 CDJ67763.1 - 0.28 9.9 13.8 0.27 9.9 13.8 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ67763.1 - 0.29 10.1 8.7 0.32 9.9 8.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 CDJ67763.1 - 0.31 10.2 1.2 0.31 10.2 1.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MMR1 PF08505.10 CDJ67763.1 - 0.46 10.7 12.6 0.48 10.7 12.6 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Ndc1_Nup PF09531.10 CDJ67763.1 - 0.71 8.5 10.7 0.71 8.5 10.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MDM10 PF12519.8 CDJ67763.1 - 1.2 8.0 8.4 1.2 7.9 8.4 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 VIT1 PF01988.19 CDJ67763.1 - 1.4 8.8 4.3 1.7 8.4 4.3 1.2 1 0 0 1 1 1 0 VIT family Hid1 PF12722.7 CDJ67763.1 - 1.8 6.6 10.4 1.7 6.7 10.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Otopetrin PF03189.13 CDJ67763.1 - 1.9 7.2 3.8 1.9 7.2 3.8 1.1 1 0 0 1 1 1 0 Otopetrin Connexin PF00029.19 CDJ67763.1 - 2.5 7.8 9.1 3.6 7.3 9.1 1.4 1 0 0 1 1 1 0 Connexin Spt20 PF12090.8 CDJ67763.1 - 2.7 7.6 37.3 5.3 6.6 37.3 1.5 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 CDJ67763.1 - 3.2 5.9 25.2 3.6 5.8 25.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Folate_carrier PF01770.18 CDJ67763.1 - 4.3 6.0 5.2 5 5.8 5.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier Borrelia_P83 PF05262.11 CDJ67763.1 - 4.3 5.7 16.3 5.5 5.4 16.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein ALMT PF11744.8 CDJ67763.1 - 4.6 6.0 8.2 5.6 5.7 8.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CCDC53 PF10152.9 CDJ67763.1 - 4.7 7.6 17.3 7.7 6.9 17.3 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex GREB1 PF15782.5 CDJ67763.1 - 5 4.1 12.2 5 4.1 12.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SprA-related PF12118.8 CDJ67763.1 - 5.5 6.0 28.1 7.6 5.6 28.1 1.2 1 0 0 1 1 1 0 SprA-related family Membralin PF09746.9 CDJ67763.1 - 8.5 5.3 6.1 8.5 5.3 6.1 1.2 1 0 0 1 1 1 0 Tumour-associated protein Asparaginase_2 PF01112.18 CDJ67763.1 - 8.7 5.3 7.5 13 4.7 7.5 1.2 1 0 0 1 1 1 0 Asparaginase DUF1764 PF08576.10 CDJ67763.1 - 8.7 7.3 13.8 1.5 9.7 9.7 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) HEAT PF02985.22 CDJ67764.1 - 0.0013 18.8 0.2 0.0013 18.8 0.2 6.8 7 0 0 7 7 7 2 HEAT repeat SR-25 PF10500.9 CDJ67764.1 - 0.0057 16.3 6.8 0.0057 16.3 6.8 11.6 10 3 0 10 10 10 3 Nuclear RNA-splicing-associated protein SyrA PF11089.8 CDJ67764.1 - 0.045 13.8 0.1 0.22 11.6 0.1 2.3 1 0 0 1 1 1 0 Exopolysaccharide production repressor RskA PF10099.9 CDJ67765.1 - 0.0023 18.3 2.1 0.0023 18.3 2.1 6.2 1 1 5 6 6 6 3 Anti-sigma-K factor rskA SARAF PF06682.12 CDJ67765.1 - 0.03 14.0 18.2 0.036 13.7 4.7 3.6 1 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 CDJ67765.1 - 0.038 15.0 29.2 0.24 12.4 0.2 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) Rxt3 PF08642.10 CDJ67765.1 - 1.8 9.4 11.5 16 6.3 0.0 3.9 4 0 0 4 4 4 0 Histone deacetylation protein Rxt3 CNDH2_N PF06278.11 CDJ67765.1 - 3.7 7.8 23.7 1.3 9.3 0.4 4.5 4 0 0 4 4 4 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Spt20 PF12090.8 CDJ67765.1 - 6.6 6.3 86.1 0.08 12.5 19.6 5.0 5 0 0 5 5 5 0 Spt20 family dsRBD2 PF17842.1 CDJ67765.1 - 7.5 6.7 15.7 0.55 10.4 1.7 3.8 4 0 0 4 4 4 0 Double-stranded RNA binding domain 2 V_ATPase_I PF01496.19 CDJ67765.1 - 7.8 4.3 20.3 1.6 6.5 0.3 3.2 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family DUF2722 PF10846.8 CDJ67766.1 - 0.0041 16.1 11.2 0.016 14.2 3.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ67766.1 - 0.029 14.5 0.3 0.029 14.5 0.3 3.6 2 1 0 2 2 1 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ67766.1 - 0.033 14.5 35.9 0.31 11.3 10.1 2.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ67766.1 - 0.13 11.9 19.4 0.95 9.0 11.1 2.3 2 0 0 2 2 2 0 Spt20 family DUF4131 PF13567.6 CDJ67766.1 - 0.15 11.7 2.6 0.2 11.3 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Folate_carrier PF01770.18 CDJ67766.1 - 0.2 10.4 0.6 0.25 10.0 0.1 1.5 2 0 0 2 2 2 0 Reduced folate carrier DUF4834 PF16118.5 CDJ67766.1 - 0.24 12.4 4.3 3.1 8.8 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ67766.1 - 0.36 10.8 5.4 0.62 10.0 1.7 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DivIC PF04977.15 CDJ67766.1 - 0.37 10.6 14.2 0.11 12.3 5.5 2.3 2 0 0 2 2 2 0 Septum formation initiator EphA2_TM PF14575.6 CDJ67766.1 - 0.63 10.9 2.2 34 5.4 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4578 PF15147.6 CDJ67766.1 - 0.87 10.5 11.8 1.2 10.0 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) MMR1 PF08505.10 CDJ67766.1 - 0.89 9.8 6.7 1.8 8.8 1.2 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein FHIPEP PF00771.20 CDJ67766.1 - 1.4 7.3 5.3 0.48 8.8 0.4 2.0 2 0 0 2 2 2 0 FHIPEP family DUF2681 PF10883.8 CDJ67766.1 - 1.5 9.2 17.3 1.1 9.7 5.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) WBP-1 PF11669.8 CDJ67766.1 - 3.2 8.4 7.3 23 5.7 0.3 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 PepSY_TM_like_2 PF16357.5 CDJ67766.1 - 4.4 7.2 5.3 1.4 8.8 0.6 2.1 2 0 0 2 2 2 0 Putative PepSY_TM-like RVP_2 PF08284.11 CDJ67767.1 - 1.2e-10 41.3 0.0 1.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ67767.1 - 2.2e-09 37.9 0.0 3.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ67767.1 - 6.7e-09 36.2 0.0 1.2e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ67767.1 - 0.00019 21.7 0.0 0.00056 20.2 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ67767.1 - 0.00022 21.0 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF3552 PF12072.8 CDJ67767.1 - 0.024 14.1 0.6 0.039 13.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF726 PF05277.12 CDJ67769.1 - 3.9 6.3 10.6 4.8 6.0 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PTH2 PF01981.16 CDJ67770.1 - 9.5e-17 61.4 0.0 9.5e-17 61.4 0.0 5.4 1 1 3 4 4 4 1 Peptidyl-tRNA hydrolase PTH2 HTH_23 PF13384.6 CDJ67771.1 - 0.0054 16.5 0.1 0.032 14.0 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 CDJ67771.1 - 0.0069 16.3 0.5 0.021 14.7 0.2 2.0 2 0 0 2 2 2 1 MarR family UPF0240 PF06784.11 CDJ67771.1 - 0.048 13.7 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) Ribosomal_60s PF00428.19 CDJ67772.1 - 5.7e-21 74.9 17.3 1e-20 74.1 17.3 1.4 1 1 0 1 1 1 1 60s Acidic ribosomal protein Totivirus_coat PF05518.11 CDJ67772.1 - 0.048 11.7 2.5 0.054 11.5 2.5 1.0 1 0 0 1 1 1 0 Totivirus coat protein DUF3824 PF12868.7 CDJ67772.1 - 2.8 8.6 5.9 3.9 8.1 5.9 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) TetR_C_29 PF17938.1 CDJ67773.1 - 3.3 7.8 13.1 6.8 6.8 4.8 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Radical_SAM_N PF08497.10 CDJ67773.1 - 8.8 5.5 10.3 9.4 5.4 10.3 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal eIF3_subunit PF08597.10 CDJ67773.1 - 9.1 6.1 15.3 12 5.7 15.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit AP2 PF00847.20 CDJ67774.1 - 2.6e-08 34.0 0.2 2.6e-08 34.0 0.2 3.7 4 0 0 4 4 4 1 AP2 domain K_channel_TID PF07941.11 CDJ67774.1 - 0.016 15.6 7.5 0.016 15.6 7.5 6.0 4 1 1 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain Surface_antigen PF11054.8 CDJ67776.1 - 1.8e-07 31.1 0.0 1.9e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Integrase_H2C2 PF17921.1 CDJ67777.1 - 0.0094 16.0 1.1 0.018 15.2 1.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Cation_ATPase_N PF00690.26 CDJ67778.1 - 1e-14 53.9 0.0 1e-14 53.9 0.0 2.4 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus PEPCK_ATP PF01293.20 CDJ67779.1 - 1e-42 146.4 0.0 1.2e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF5134 PF17197.4 CDJ67780.1 - 0.00047 20.1 0.3 0.00055 19.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5134) LEDGF PF11467.8 CDJ67780.1 - 0.011 15.4 0.7 0.011 15.4 0.7 1.9 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) DUF4726 PF15855.5 CDJ67780.1 - 0.014 15.6 2.4 0.014 15.6 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) RskA PF10099.9 CDJ67780.1 - 0.098 12.9 9.2 0.15 12.3 9.2 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Sulfatase_C PF14707.6 CDJ67780.1 - 2 9.2 8.5 8.7 7.1 3.6 2.1 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase EIF4E-T PF10477.9 CDJ67780.1 - 4.1 6.1 9.9 4.9 5.8 9.9 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Ribosomal_60s PF00428.19 CDJ67780.1 - 5.8 7.6 9.1 0.27 11.8 2.9 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ67780.1 - 6.5 6.6 17.7 7.8 6.4 17.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH PF17917.1 CDJ67784.1 - 1.9e-29 102.0 0.0 4e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ67784.1 - 5.2e-29 100.2 0.1 9.6e-29 99.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ67784.1 - 1.9e-21 76.6 0.0 3.3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Es2 PF09751.9 CDJ67785.1 - 0.067 12.9 3.7 0.091 12.5 3.7 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 PIEZO PF15917.5 CDJ67785.1 - 0.38 10.2 4.4 0.43 10.0 4.4 1.1 1 0 0 1 1 1 0 Piezo RskA PF10099.9 CDJ67786.1 - 1.1 9.5 39.8 36 4.6 39.8 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA CT47 PF15623.6 CDJ67786.1 - 1.3 8.8 16.1 1.5 8.6 16.1 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Hamartin PF04388.12 CDJ67786.1 - 2.7 6.6 10.0 2.9 6.4 10.0 1.0 1 0 0 1 1 1 0 Hamartin protein FAM60A PF15396.6 CDJ67786.1 - 3.9 7.4 6.4 4.8 7.1 6.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Peroxin-13_N PF04088.13 CDJ67786.1 - 5.6 7.2 8.8 0.96 9.7 0.7 2.0 2 0 0 2 2 2 0 Peroxin 13, N-terminal region TFIIA PF03153.13 CDJ67786.1 - 8.9 6.2 33.5 10 6.0 33.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CDJ67787.1 - 4.9e-15 55.6 0.0 6.5e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ67787.1 - 2.5e-05 23.7 0.0 3.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Bclt PF15318.6 CDJ67788.1 - 0.023 14.5 3.6 0.027 14.3 3.6 1.0 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis TraT PF05818.12 CDJ67788.1 - 0.047 13.4 9.1 0.065 12.9 9.1 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Tic110 PF16940.5 CDJ67788.1 - 0.48 8.9 15.8 0.5 8.8 15.8 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF3597 PF12200.8 CDJ67788.1 - 1 9.9 8.7 1.5 9.4 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF2057 PF09829.9 CDJ67788.1 - 1.1 9.4 8.9 1.3 9.2 8.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) R_equi_Vir PF05526.11 CDJ67788.1 - 1.6 8.5 8.7 2.4 8.0 8.7 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF2946 PF11162.8 CDJ67789.1 - 0.023 15.4 5.9 0.028 15.1 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF755 PF05501.11 CDJ67789.1 - 0.063 13.6 9.3 0.097 12.9 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ67789.1 - 0.21 11.2 14.7 0.22 11.1 14.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PP2C PF00481.21 CDJ67791.1 - 1.2e-17 64.4 0.1 1.4e-17 64.2 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C FAM199X PF15814.5 CDJ67791.1 - 0.031 13.4 10.9 0.034 13.2 10.9 1.1 1 0 0 1 1 1 0 Protein family FAM199X Ald_Xan_dh_C2 PF02738.18 CDJ67791.1 - 0.11 11.0 0.9 0.13 10.7 0.9 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase SPX PF03105.19 CDJ67791.1 - 0.13 12.2 6.7 0.13 12.1 6.7 1.1 1 0 0 1 1 1 0 SPX domain AF-4 PF05110.13 CDJ67791.1 - 0.62 8.1 11.8 0.63 8.1 11.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.11 CDJ67791.1 - 6.2 5.0 5.3 6 5.0 5.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ67791.1 - 8.2 6.0 21.9 13 5.3 21.9 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SpoIIE PF07228.12 CDJ67792.1 - 0.019 14.9 1.8 0.039 13.9 0.0 1.9 1 1 1 2 2 2 0 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CDJ67792.1 - 0.044 13.4 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C T2SSM PF04612.12 CDJ67792.1 - 1 9.4 7.4 1.8 8.6 7.4 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M SSP160 PF06933.11 CDJ67792.1 - 3 6.0 19.0 8.9 4.4 0.1 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Spc7 PF08317.11 CDJ67794.1 - 0.0055 15.6 6.8 0.0068 15.3 6.8 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF5320 PF17253.2 CDJ67794.1 - 0.0057 17.7 5.7 0.53 11.4 0.7 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5320) bZIP_Maf PF03131.17 CDJ67794.1 - 0.016 15.8 7.0 0.029 14.9 1.4 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor Mod_r PF07200.13 CDJ67794.1 - 0.092 12.8 7.3 0.46 10.6 0.9 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein S6OS1 PF15676.5 CDJ67794.1 - 0.097 11.1 1.8 0.11 10.9 1.8 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family ERM PF00769.19 CDJ67794.1 - 0.17 11.6 12.1 0.21 11.4 12.1 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Csm1_N PF18504.1 CDJ67794.1 - 0.31 11.4 9.3 0.19 12.1 2.2 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 CDJ67794.1 - 0.43 10.8 6.9 0.41 10.9 1.2 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 CDJ67794.1 - 0.5 10.9 13.9 0.4 11.2 3.8 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Macoilin PF09726.9 CDJ67794.1 - 0.78 8.2 9.9 2.3 6.7 10.0 1.6 1 1 0 1 1 1 0 Macoilin family Atg14 PF10186.9 CDJ67794.1 - 1.2 8.1 10.1 1.4 7.9 10.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 CDJ67794.1 - 4.8 7.5 7.9 7.5 6.9 1.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YabA PF06156.13 CDJ67794.1 - 4.9 7.8 5.6 67 4.2 5.6 2.0 1 1 0 1 1 1 0 Initiation control protein YabA HEAT_2 PF13646.6 CDJ67795.1 - 1.2e-14 54.4 5.9 2.6e-11 43.7 2.0 2.0 1 1 1 2 2 2 2 HEAT repeats PC_rep PF01851.22 CDJ67795.1 - 2.4e-07 30.9 0.2 0.004 17.5 0.0 2.3 2 0 0 2 2 2 2 Proteasome/cyclosome repeat HEAT PF02985.22 CDJ67795.1 - 5.7e-06 26.1 2.7 0.15 12.4 0.1 3.8 4 0 0 4 4 4 2 HEAT repeat IBN_N PF03810.19 CDJ67795.1 - 0.0026 17.6 0.0 1 9.3 0.0 2.1 1 1 1 2 2 2 2 Importin-beta N-terminal domain DUF4456 PF14644.6 CDJ67796.1 - 0.0034 17.1 6.0 0.0034 17.1 6.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4456) EphA2_TM PF14575.6 CDJ67796.1 - 0.1 13.5 5.5 0.67 10.9 0.5 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Siah-Interact_N PF09032.11 CDJ67796.1 - 0.21 11.9 12.1 0.37 11.1 2.0 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal DUF2149 PF09919.9 CDJ67796.1 - 0.45 10.8 3.5 0.48 10.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) CDH1_2_SANT_HL1 PF18375.1 CDJ67796.1 - 0.46 11.2 3.3 2.7 8.7 0.2 2.1 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 DUF2076 PF09849.9 CDJ67796.1 - 0.54 10.3 28.4 0.61 10.1 28.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Presenilin PF01080.17 CDJ67796.1 - 0.64 8.7 8.6 0.71 8.6 8.6 1.1 1 0 0 1 1 1 0 Presenilin STAG PF08514.11 CDJ67796.1 - 0.71 9.8 7.0 0.73 9.8 0.1 2.2 2 0 0 2 2 2 0 STAG domain GRP PF07172.11 CDJ67796.1 - 0.72 10.6 3.5 3.1 8.6 0.5 2.1 2 0 0 2 2 2 0 Glycine rich protein family DUF4834 PF16118.5 CDJ67796.1 - 0.73 10.8 12.2 3.8 8.5 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ67796.1 - 1.6 6.5 7.5 1.8 6.4 7.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SARAF PF06682.12 CDJ67796.1 - 2.9 7.4 11.8 3.5 7.2 11.8 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4407 PF14362.6 CDJ67796.1 - 3.6 6.9 11.7 5.4 6.3 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 CDJ67796.1 - 3.7 7.5 6.9 4.1 7.4 6.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 CDJ67796.1 - 7.5 4.5 7.9 7.9 4.5 7.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LEA_3 PF03242.13 CDJ67796.1 - 7.9 7.3 7.6 10 6.9 0.1 2.1 1 1 1 2 2 2 0 Late embryogenesis abundant protein zf-CCHC PF00098.23 CDJ67797.1 - 1.1e-07 31.6 11.0 3e-06 27.0 2.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ67797.1 - 0.0019 18.0 0.6 0.0019 18.0 0.6 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ67797.1 - 0.0043 17.0 0.2 0.0043 17.0 0.2 2.3 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ67797.1 - 0.016 15.0 1.9 0.016 15.0 1.9 2.2 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CDJ67797.1 - 0.097 13.0 5.3 0.2 12.0 5.3 1.5 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_4 PF14392.6 CDJ67797.1 - 0.12 12.1 5.6 0.3 10.8 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ67797.1 - 1.1 9.0 10.9 1.4 8.6 1.8 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RskA PF10099.9 CDJ67798.1 - 1.7e-05 25.2 23.3 6.8e-05 23.2 11.4 2.1 2 0 0 2 2 2 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ67798.1 - 0.00059 19.5 22.6 0.0076 15.9 4.4 2.1 2 0 0 2 2 2 2 Spt20 family SUIM_assoc PF16619.5 CDJ67798.1 - 0.017 15.1 32.0 0.27 11.3 11.4 2.6 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ67798.1 - 0.021 13.8 1.0 0.021 13.8 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ67798.1 - 0.11 12.4 21.4 0.14 12.1 5.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.6 CDJ67798.1 - 0.34 10.1 9.7 0.11 11.7 1.9 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4834 PF16118.5 CDJ67798.1 - 1.6 9.7 9.1 7.2 7.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2489 PF10675.9 CDJ67798.1 - 1.6 8.7 17.2 1.2 9.1 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) RVT_1 PF00078.27 CDJ67799.1 - 6.5e-15 55.2 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3552 PF12072.8 CDJ67799.1 - 0.032 13.7 0.3 0.044 13.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Retrotrans_gag PF03732.17 CDJ67800.1 - 0.017 15.4 0.1 0.094 13.0 0.0 2.2 2 1 1 3 3 3 0 Retrotransposon gag protein NUC153 PF08159.12 CDJ67802.1 - 0.00049 19.9 0.3 0.0012 18.7 0.3 1.7 1 0 0 1 1 1 1 NUC153 domain RskA PF10099.9 CDJ67802.1 - 0.00058 20.2 0.6 0.00058 20.2 0.6 3.3 2 1 1 3 3 3 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ67802.1 - 0.0019 17.8 5.7 0.0019 17.8 5.7 3.3 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ67802.1 - 0.11 13.1 24.9 0.065 13.8 7.1 2.6 2 0 0 2 2 2 0 TCP family transcription factor CCSAP PF15748.5 CDJ67802.1 - 0.12 12.5 19.7 0.14 12.3 1.5 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Filament_head PF04732.14 CDJ67802.1 - 0.44 11.5 32.0 1.3 10.0 20.0 2.8 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region FAM199X PF15814.5 CDJ67802.1 - 4.7 6.2 27.4 0.15 11.1 11.2 2.3 2 0 0 2 2 2 0 Protein family FAM199X EOS1 PF12326.8 CDJ67802.1 - 7.3 6.5 8.4 5.8 6.8 1.3 2.4 2 1 0 2 2 2 0 N-glycosylation protein Period_C PF12114.8 CDJ67802.1 - 9.3 5.8 26.2 2.8 7.5 13.1 2.8 3 0 0 3 3 3 0 Period protein 2/3C-terminal region Macoilin PF09726.9 CDJ67804.1 - 0.046 12.3 41.8 0.07 11.7 41.8 1.2 1 0 0 1 1 1 0 Macoilin family Utp14 PF04615.13 CDJ67804.1 - 0.074 11.6 28.3 0.084 11.4 28.3 1.0 1 0 0 1 1 1 0 Utp14 protein Plasmodium_Vir PF05795.11 CDJ67804.1 - 0.45 9.9 23.8 0.67 9.3 23.6 1.3 1 1 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 CDJ67804.1 - 0.49 10.3 43.4 0.64 9.9 43.4 1.1 1 0 0 1 1 1 0 SPX domain TFIIA PF03153.13 CDJ67804.1 - 0.99 9.3 36.2 1.3 8.9 36.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Draxin PF15550.6 CDJ67804.1 - 1 9.2 18.5 1.2 8.9 18.5 1.1 1 0 0 1 1 1 0 Draxin Red1 PF07964.11 CDJ67804.1 - 3 6.0 28.9 3.4 5.8 28.9 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Sin_N PF04801.13 CDJ67804.1 - 3.9 6.6 24.0 4.8 6.3 24.0 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Ndc1_Nup PF09531.10 CDJ67804.1 - 5.7 5.5 29.4 9.5 4.8 29.4 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LAP1C PF05609.12 CDJ67804.1 - 5.8 5.9 29.3 7.2 5.6 29.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RHINO PF15319.6 CDJ67804.1 - 6.3 6.8 27.4 7.5 6.5 27.4 1.0 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein ATF7IP_BD PF16788.5 CDJ67804.1 - 9.3 6.3 39.8 13 5.8 39.8 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain DHHC PF01529.20 CDJ67805.1 - 2.2e-10 40.8 0.2 3.4e-10 40.1 0.2 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase RskA PF10099.9 CDJ67805.1 - 0.013 15.8 16.3 0.013 15.8 16.3 6.7 3 3 2 5 5 5 0 Anti-sigma-K factor rskA Roughex PF06020.11 CDJ67805.1 - 3.6 6.6 6.6 6 5.9 6.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein 14-3-3 PF00244.20 CDJ67806.1 - 7e-37 127.1 0.0 7.8e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 14-3-3 protein PG_binding_1 PF01471.18 CDJ67806.1 - 0.057 13.6 0.1 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Putative peptidoglycan binding domain CSTF_C PF14304.6 CDJ67806.1 - 0.087 12.4 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal TPR_14 PF13428.6 CDJ67806.1 - 0.21 12.5 7.0 1.3 10.1 0.6 2.9 2 2 1 3 3 3 0 Tetratricopeptide repeat ATP-synt_C PF00137.21 CDJ67807.1 - 0.038 14.3 1.9 0.065 13.6 1.9 1.4 1 0 0 1 1 1 0 ATP synthase subunit C SR-25 PF10500.9 CDJ67808.1 - 0.0042 16.7 22.2 0.0042 16.7 22.2 5.3 2 2 3 5 5 5 2 Nuclear RNA-splicing-associated protein SAPS PF04499.15 CDJ67809.1 - 0.12 11.2 21.6 0.13 11.0 21.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1645 PF07816.11 CDJ67809.1 - 0.25 11.9 23.4 0.32 11.5 23.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DUF572 PF04502.13 CDJ67809.1 - 2.6 7.6 29.5 4.3 6.9 29.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peroxin-3 PF04882.12 CDJ67809.1 - 2.6 6.9 33.9 3.9 6.4 33.9 1.3 1 0 0 1 1 1 0 Peroxin-3 Methyltransf_34 PF11312.8 CDJ67809.1 - 5.3 6.2 22.1 8.1 5.6 21.5 1.5 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase EF-hand_7 PF13499.6 CDJ67810.1 - 5.7e-07 29.9 1.4 8.4e-07 29.4 0.8 1.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ67810.1 - 7.9e-06 25.1 2.1 7.3e-05 22.0 0.6 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CDJ67810.1 - 1.9e-05 24.2 1.6 0.0068 16.3 0.5 2.7 1 1 2 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CDJ67810.1 - 0.0002 20.7 0.9 0.00045 19.6 0.9 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CDJ67810.1 - 0.0012 18.7 0.1 0.0024 17.7 0.1 1.6 1 1 0 1 1 1 1 EF-hand domain pair NuA4 PF09340.10 CDJ67810.1 - 0.043 13.7 0.2 0.061 13.2 0.2 1.4 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 SPARC_Ca_bdg PF10591.9 CDJ67810.1 - 0.065 13.6 0.7 0.078 13.3 0.7 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region TUTF7_u4 PF16631.5 CDJ67810.1 - 0.12 13.0 1.8 6.1 7.6 0.3 2.1 1 1 1 2 2 2 0 Unstructured region 4 on terminal uridylyltransferase 7 Macoilin PF09726.9 CDJ67812.1 - 0.00024 19.8 12.4 0.00052 18.7 12.4 1.5 1 0 0 1 1 1 1 Macoilin family Sporozoite_P67 PF05642.11 CDJ67812.1 - 0.00034 18.8 11.7 0.00054 18.2 11.7 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Spt20 PF12090.8 CDJ67812.1 - 0.0015 18.2 28.2 0.078 12.6 14.3 2.2 2 0 0 2 2 2 2 Spt20 family V_ATPase_I PF01496.19 CDJ67812.1 - 0.0031 15.5 1.1 0.0052 14.8 1.1 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ67812.1 - 0.0067 16.5 30.9 0.032 14.2 10.3 2.7 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ67812.1 - 0.043 13.4 14.7 0.86 9.1 12.6 2.9 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist LRV PF01816.17 CDJ67812.1 - 0.099 13.1 0.3 0.099 13.1 0.3 3.7 3 0 0 3 3 3 0 Leucine rich repeat variant Otopetrin PF03189.13 CDJ67812.1 - 0.1 11.4 2.3 0.17 10.6 2.3 1.3 1 0 0 1 1 1 0 Otopetrin FAM199X PF15814.5 CDJ67812.1 - 0.32 10.0 28.0 0.065 12.3 23.1 2.1 2 0 0 2 2 2 0 Protein family FAM199X DUF1645 PF07816.11 CDJ67812.1 - 0.41 11.2 21.6 0.16 12.6 17.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) HEAT PF02985.22 CDJ67812.1 - 0.63 10.4 4.3 8.5 6.9 0.1 4.7 4 0 0 4 4 3 0 HEAT repeat DAG_kinase_N PF14513.6 CDJ67812.1 - 0.76 10.0 10.4 1 9.6 7.1 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Apt1 PF10351.9 CDJ67812.1 - 0.76 8.6 19.3 0.086 11.7 15.1 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain U3snoRNP10 PF12397.8 CDJ67812.1 - 1.6 9.1 6.1 11 6.4 0.0 3.8 2 1 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Neur_chan_memb PF02932.16 CDJ67812.1 - 2.9 7.9 6.6 5.5 7.0 3.3 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ67812.1 - 3.4 7.4 12.7 5.9 6.6 0.3 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2681 PF10883.8 CDJ67812.1 - 3.9 8.0 16.5 7.1 7.1 6.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Cwf_Cwc_15 PF04889.12 CDJ67812.1 - 8.3 6.1 14.1 0.88 9.3 3.8 2.9 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein PGA2 PF07543.12 CDJ67812.1 - 8.9 6.3 11.3 3.9 7.4 1.9 3.3 3 0 0 3 3 3 0 Protein trafficking PGA2 Phage_holin_3_6 PF07332.11 CDJ67814.1 - 0.00017 21.6 1.1 0.00017 21.6 1.1 1.4 2 0 0 2 2 1 1 Putative Actinobacterial Holin-X, holin superfamily III SARAF PF06682.12 CDJ67814.1 - 0.055 13.1 10.9 0.063 12.9 10.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Myf5 PF12232.8 CDJ67814.1 - 0.13 13.1 0.7 0.2 12.4 0.7 1.3 1 0 0 1 1 1 0 Myogenic determination factor 5 Connexin PF00029.19 CDJ67814.1 - 0.27 11.0 5.1 0.33 10.7 5.1 1.1 1 0 0 1 1 1 0 Connexin DUF3537 PF12056.8 CDJ67814.1 - 0.38 9.5 7.1 0.63 8.8 7.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3537) Cyclin_C PF02984.19 CDJ67814.1 - 0.65 10.1 5.0 0.96 9.5 5.0 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain Zip PF02535.22 CDJ67814.1 - 0.75 9.0 6.3 0.89 8.7 6.3 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter DUF1980 PF09323.10 CDJ67814.1 - 1 9.3 4.8 1.5 8.7 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RR_TM4-6 PF06459.12 CDJ67814.1 - 1.7 8.4 11.9 1.9 8.3 11.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ67814.1 - 2 7.1 14.3 2.4 6.8 14.3 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ67814.1 - 2.1 8.3 35.6 2.2 8.2 35.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 CDJ67814.1 - 2.1 8.6 16.5 2.4 8.4 16.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein V_ATPase_I PF01496.19 CDJ67814.1 - 4 5.3 10.7 4.7 5.0 10.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF-3_zeta PF05091.12 CDJ67814.1 - 6.3 5.6 15.5 6.7 5.6 15.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ67814.1 - 7 6.6 12.3 8.5 6.3 12.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 CDJ67814.1 - 7.4 4.7 22.8 7.7 4.7 22.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_1 PF00076.22 CDJ67816.1 - 6.2e-14 51.6 0.0 1.5e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 CDJ67816.1 - 1.3e-08 34.8 6.7 2.3e-08 34.0 6.7 1.4 1 0 0 1 1 1 1 WW domain KASH PF10541.9 CDJ67816.1 - 0.082 13.2 2.3 0.15 12.3 2.3 1.3 1 0 0 1 1 1 0 Nuclear envelope localisation domain INO80_Ies4 PF08193.11 CDJ67817.1 - 0.22 11.5 12.8 0.43 10.5 8.2 2.2 2 0 0 2 2 2 0 INO80 complex subunit Ies4 SR-25 PF10500.9 CDJ67817.1 - 0.49 10.0 8.2 0.086 12.4 3.3 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ67819.1 - 0.0004 19.5 5.4 0.0004 19.5 5.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) RMI2 PF16100.5 CDJ67819.1 - 0.00067 19.5 0.1 0.00067 19.5 0.1 2.5 1 1 0 2 2 2 1 RecQ-mediated genome instability protein 2 MAM33 PF02330.16 CDJ67819.1 - 0.014 15.4 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial glycoprotein DUF4834 PF16118.5 CDJ67819.1 - 0.017 16.1 0.9 0.017 16.1 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1344 PF07076.11 CDJ67819.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Spt20 PF12090.8 CDJ67819.1 - 0.8 9.3 29.9 0.91 9.1 20.8 2.2 2 0 0 2 2 2 0 Spt20 family DUF775 PF05603.12 CDJ67819.1 - 1.1 8.7 7.0 0.21 11.1 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Activator_LAG-3 PF11498.8 CDJ67819.1 - 6.6 5.6 30.5 3.1 6.6 22.7 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 RskA PF10099.9 CDJ67819.1 - 8.4 6.6 63.4 0.67 10.2 16.5 4.0 1 1 2 3 3 3 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ67820.1 - 0.095 12.3 12.3 0.14 11.7 12.3 1.2 1 0 0 1 1 1 0 Spt20 family SPX PF03105.19 CDJ67820.1 - 0.24 11.3 11.0 0.41 10.5 11.0 1.3 1 1 0 1 1 1 0 SPX domain Retrotrans_gag PF03732.17 CDJ67821.1 - 0.063 13.6 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Retrotrans_gag PF03732.17 CDJ67822.1 - 0.0012 19.0 0.1 0.0053 17.0 0.0 2.1 3 0 0 3 3 3 1 Retrotransposon gag protein rve PF00665.26 CDJ67823.1 - 5.9e-13 49.1 0.0 6.9e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ67823.1 - 0.084 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 CDJ67824.1 - 4.5e-13 49.2 0.0 7.5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3552 PF12072.8 CDJ67824.1 - 0.097 12.1 1.1 0.14 11.5 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Spt20 PF12090.8 CDJ67826.1 - 0.049 13.2 8.8 0.045 13.4 8.8 1.1 1 0 0 1 1 1 0 Spt20 family Glyco_tran_10_N PF17039.5 CDJ67826.1 - 0.06 13.8 0.1 0.07 13.6 0.1 1.1 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal ANAPC_CDC26 PF10471.9 CDJ67826.1 - 0.16 12.8 11.1 0.22 12.4 11.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Pribosyltran_N PF13793.6 CDJ67827.1 - 1.2e-47 160.6 0.1 7.2e-47 158.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CDJ67827.1 - 1.2e-21 77.6 0.2 2.3e-21 76.7 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CDJ67827.1 - 3.2e-14 52.7 0.2 6e-14 51.9 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CDJ67827.1 - 0.0036 16.8 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase TFIIA PF03153.13 CDJ67829.1 - 0.0057 16.7 19.0 0.0082 16.2 19.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ67829.1 - 0.6 10.0 5.2 0.82 9.6 5.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 CDJ67829.1 - 5.9 5.0 13.5 6.8 4.8 13.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RT_RNaseH PF17917.1 CDJ67830.1 - 4.3e-30 104.1 0.1 7.4e-30 103.3 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ67830.1 - 1.2e-29 102.2 0.1 2e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ67830.1 - 8.1e-14 51.7 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 CDJ67830.1 - 0.036 13.9 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like PH PF00169.29 CDJ67831.1 - 0.00014 22.3 0.1 0.00028 21.3 0.1 1.5 1 0 0 1 1 1 1 PH domain zf-RING_7 PF02591.15 CDJ67831.1 - 0.03 14.5 4.7 0.72 10.1 0.0 3.5 3 0 0 3 3 3 0 C4-type zinc ribbon domain DUF5342 PF17277.2 CDJ67831.1 - 0.074 13.4 1.2 0.12 12.7 1.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5342) PH_11 PF15413.6 CDJ67831.1 - 0.1 13.0 0.5 0.27 11.7 0.5 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain eIF-3_zeta PF05091.12 CDJ67833.1 - 0.15 11.0 11.4 0.18 10.8 11.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_60s PF00428.19 CDJ67833.1 - 1 10.0 23.9 4.2 8.0 12.2 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF572 PF04502.13 CDJ67833.1 - 2.9 7.4 15.9 2.4 7.7 11.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Spt20 PF12090.8 CDJ67833.1 - 3.5 7.2 34.0 7.4 6.1 34.0 1.5 1 0 0 1 1 1 0 Spt20 family Connexin PF00029.19 CDJ67833.1 - 5.2 6.8 7.5 11 5.7 7.5 1.5 1 0 0 1 1 1 0 Connexin Apt1 PF10351.9 CDJ67833.1 - 8.1 5.2 19.4 14 4.4 0.2 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF2722 PF10846.8 CDJ67834.1 - 0.0016 17.4 1.7 0.0016 17.4 1.7 5.5 4 2 0 4 4 4 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ67835.1 - 0.0051 16.4 12.9 0.0051 16.4 12.9 1.2 1 0 0 1 1 1 1 Spt20 family DivIC PF04977.15 CDJ67835.1 - 0.0058 16.4 4.9 0.0072 16.1 4.9 1.2 1 0 0 1 1 1 1 Septum formation initiator Androgen_recep PF02166.16 CDJ67835.1 - 0.031 13.1 15.7 0.032 13.1 15.7 1.2 1 0 0 1 1 1 0 Androgen receptor DUF1980 PF09323.10 CDJ67835.1 - 0.076 12.9 0.8 0.083 12.8 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF5563 PF17718.1 CDJ67835.1 - 0.12 12.0 2.6 0.13 11.8 2.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5563) TFIIA PF03153.13 CDJ67835.1 - 0.2 11.6 15.9 0.19 11.7 15.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit G0-G1_switch_2 PF15103.6 CDJ67835.1 - 0.24 11.8 3.2 0.26 11.7 3.2 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF2722 PF10846.8 CDJ67835.1 - 0.28 10.1 13.3 0.39 9.6 13.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF5345 PF17280.2 CDJ67835.1 - 0.98 9.4 6.7 1.8 8.6 6.3 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Presenilin PF01080.17 CDJ67835.1 - 1.1 8.0 5.0 1.1 8.0 5.0 1.0 1 0 0 1 1 1 0 Presenilin GET2 PF08690.10 CDJ67835.1 - 1.6 8.4 8.5 1.8 8.2 8.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DUF1180 PF06679.12 CDJ67835.1 - 3.4 8.1 7.6 3.7 7.9 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RNase_Zc3h12a PF11977.8 CDJ67836.1 - 4.9e-16 58.9 2.6 4.8e-12 45.9 0.0 3.6 3 1 1 4 4 4 2 Zc3h12a-like Ribonuclease NYN domain DUF755 PF05501.11 CDJ67836.1 - 3.1e-05 24.2 36.3 3.1e-05 24.2 36.3 8.6 7 2 0 8 8 8 1 Domain of unknown function (DUF755) TFIIA PF03153.13 CDJ67837.1 - 0.0047 17.0 31.5 0.0047 17.0 31.5 4.2 3 1 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit LCD1 PF09798.9 CDJ67837.1 - 0.011 14.3 0.0 6 5.2 0.0 2.7 2 1 0 2 2 2 0 DNA damage checkpoint protein RRM_1 PF00076.22 CDJ67838.1 - 1.8e-24 85.3 0.2 1e-11 44.4 0.0 4.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RskA PF10099.9 CDJ67838.1 - 0.0015 18.8 15.4 0.0015 18.8 15.4 16.9 3 2 9 13 13 13 3 Anti-sigma-K factor rskA DUF908 PF06012.12 CDJ67838.1 - 0.0031 17.0 7.6 0.0031 17.0 7.6 9.1 5 2 1 6 6 6 1 Domain of Unknown Function (DUF908) TFIIA PF03153.13 CDJ67838.1 - 0.0037 17.3 35.1 0.0037 17.3 35.1 9.4 3 1 4 9 9 9 2 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ67839.1 - 0.015 13.4 20.2 0.023 12.8 20.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Chorion_2 PF03964.15 CDJ67839.1 - 0.023 15.5 6.3 0.023 15.5 6.3 1.5 2 0 0 2 2 2 0 Chorion family 2 Presenilin PF01080.17 CDJ67839.1 - 0.037 12.8 0.3 0.044 12.5 0.3 1.1 1 0 0 1 1 1 0 Presenilin SurA_N_2 PF13623.6 CDJ67839.1 - 0.096 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 SurA N-terminal domain DUF508 PF04370.12 CDJ67839.1 - 0.21 11.3 6.0 0.29 10.9 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF1645 PF07816.11 CDJ67839.1 - 0.42 11.2 15.4 0.49 10.9 8.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF5423 PF17461.2 CDJ67839.1 - 0.92 8.3 14.0 1.3 7.8 14.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Secretin_N_2 PF07655.13 CDJ67839.1 - 1 10.0 14.3 0.61 10.7 11.0 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain DUF515 PF04415.12 CDJ67839.1 - 3.8 5.8 9.1 5.4 5.3 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PBP_sp32 PF07222.12 CDJ67839.1 - 4.9 6.5 8.6 1 8.8 5.3 1.4 1 1 0 1 1 1 0 Proacrosin binding protein sp32 DUF2722 PF10846.8 CDJ67840.1 - 0.0017 17.4 17.2 0.0019 17.3 17.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) dsDNA_bind PF01984.20 CDJ67840.1 - 0.0053 17.0 10.8 0.0054 17.0 10.8 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain TFIIA PF03153.13 CDJ67840.1 - 0.025 14.6 17.4 0.023 14.7 17.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CDJ67840.1 - 0.032 13.6 1.7 0.033 13.6 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CobT PF06213.12 CDJ67840.1 - 0.047 13.1 8.5 0.037 13.4 8.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 CDJ67840.1 - 0.051 12.4 5.3 0.05 12.4 5.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S49_N PF08496.10 CDJ67840.1 - 0.066 13.3 2.6 0.078 13.0 2.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SpoIIP PF07454.11 CDJ67840.1 - 0.09 12.2 4.6 0.075 12.5 4.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2368 PF10166.9 CDJ67840.1 - 0.21 11.2 4.9 0.24 11.0 4.9 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) DUF4770 PF15994.5 CDJ67840.1 - 0.21 11.8 6.6 0.21 11.8 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF1645 PF07816.11 CDJ67840.1 - 0.32 11.6 12.4 0.38 11.3 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ67840.1 - 0.48 10.0 30.0 0.61 9.7 30.0 1.2 1 0 0 1 1 1 0 Spt20 family MscS_TM PF12794.7 CDJ67840.1 - 0.65 8.8 4.1 0.6 8.9 4.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Roughex PF06020.11 CDJ67840.1 - 0.75 8.8 10.3 0.66 9.0 10.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Suf PF05843.14 CDJ67840.1 - 0.75 9.7 8.9 0.68 9.9 8.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.10 CDJ67840.1 - 0.96 8.0 18.8 0.89 8.2 18.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 CDJ67840.1 - 1 8.0 8.4 0.95 8.2 8.4 1.1 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.8 CDJ67840.1 - 1.3 8.7 7.3 1.6 8.5 7.3 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Band_3_cyto PF07565.13 CDJ67840.1 - 1.7 8.4 6.1 1.6 8.4 6.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex14_N PF04695.13 CDJ67840.1 - 2.8 8.6 15.8 1.1 9.9 13.9 1.4 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.19 CDJ67840.1 - 3.1 5.6 6.2 3 5.7 6.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lin-8 PF03353.15 CDJ67840.1 - 3.2 7.2 13.6 3.5 7.1 13.6 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NST1 PF13945.6 CDJ67840.1 - 6.1 6.9 17.2 7.3 6.6 17.2 1.2 1 1 0 1 1 1 0 Salt tolerance down-regulator Apt1 PF10351.9 CDJ67840.1 - 7.9 5.2 10.6 8.4 5.1 10.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain TERB2 PF15101.6 CDJ67840.1 - 8.5 6.4 14.0 12 5.8 14.0 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spore_coat_CotO PF14153.6 CDJ67841.1 - 0.0013 18.7 13.2 0.0013 18.7 13.2 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Spem1 PF15670.5 CDJ67841.1 - 0.0083 15.7 6.5 0.0095 15.5 6.5 1.1 1 0 0 1 1 1 1 Spermatid maturation protein 1 TFIIA PF03153.13 CDJ67841.1 - 0.037 14.0 29.5 0.041 13.9 29.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tuberin PF03542.16 CDJ67841.1 - 0.042 13.0 0.9 0.045 12.9 0.9 1.1 1 0 0 1 1 1 0 Tuberin Presenilin PF01080.17 CDJ67841.1 - 0.056 12.2 14.0 0.056 12.2 14.0 1.0 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 CDJ67841.1 - 0.11 12.6 11.7 0.14 12.3 11.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Ndc1_Nup PF09531.10 CDJ67841.1 - 0.12 11.0 9.4 0.12 11.0 9.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 CDJ67841.1 - 0.27 10.0 10.0 0.29 9.9 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NPR3 PF03666.13 CDJ67841.1 - 0.3 9.8 12.0 0.35 9.6 12.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PAT1 PF09770.9 CDJ67841.1 - 0.49 8.6 22.5 0.56 8.4 22.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOG2 PF10428.9 CDJ67841.1 - 0.5 9.5 14.2 0.52 9.4 14.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ALMT PF11744.8 CDJ67841.1 - 1.1 8.0 8.5 1.2 7.9 8.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter BORG_CEP PF14957.6 CDJ67841.1 - 1.3 10.2 7.4 1.5 10.0 7.4 1.2 1 0 0 1 1 1 0 Cdc42 effector DUF4407 PF14362.6 CDJ67841.1 - 1.4 8.2 10.8 1.7 7.9 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribonuc_P_40 PF08584.11 CDJ67841.1 - 1.5 8.0 8.5 1.7 7.9 8.5 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Band_3_cyto PF07565.13 CDJ67841.1 - 1.6 8.4 9.9 2 8.2 9.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MDM10 PF12519.8 CDJ67841.1 - 1.6 7.5 10.5 1.9 7.3 10.5 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Hid1 PF12722.7 CDJ67841.1 - 1.7 6.7 14.6 2 6.5 14.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.12 CDJ67841.1 - 1.8 7.4 12.9 2 7.3 12.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.22 CDJ67841.1 - 2.1 7.5 9.2 2.2 7.4 9.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Lin-8 PF03353.15 CDJ67841.1 - 2.8 7.4 15.7 3 7.3 15.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Tim54 PF11711.8 CDJ67841.1 - 2.9 6.6 10.9 3.3 6.4 10.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hydin_ADK PF17213.3 CDJ67841.1 - 3.4 7.9 13.7 4 7.7 13.7 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF4175 PF13779.6 CDJ67841.1 - 3.6 5.4 25.7 3.6 5.4 25.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Membralin PF09746.9 CDJ67841.1 - 3.9 6.4 7.1 4.4 6.3 7.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein GREB1 PF15782.5 CDJ67841.1 - 4.6 4.2 15.1 4.6 4.2 15.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Gastrin PF00918.17 CDJ67841.1 - 4.9 8.1 11.9 8.2 7.4 11.9 1.4 1 0 0 1 1 1 0 Gastrin/cholecystokinin family CCDC53 PF10152.9 CDJ67841.1 - 5.4 7.4 19.3 8.1 6.8 19.3 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FAM60A PF15396.6 CDJ67841.1 - 5.4 7.0 11.7 6.8 6.6 11.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 CDJ67841.1 - 6 5.8 15.8 7 5.6 15.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S49_N PF08496.10 CDJ67841.1 - 6.1 6.9 9.7 8.8 6.4 9.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Paramyxo_ncap PF00973.19 CDJ67841.1 - 6.1 5.6 9.0 5.7 5.7 9.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Dicty_REP PF05086.12 CDJ67841.1 - 6.5 4.6 13.2 7.2 4.5 13.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DAG_kinase_N PF14513.6 CDJ67841.1 - 7.5 6.7 14.3 10 6.3 14.3 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus SPATA3 PF15662.5 CDJ67841.1 - 9.1 6.9 18.1 10 6.7 18.1 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Methyltransf_32 PF13679.6 CDJ67841.1 - 9.2 6.2 14.2 13 5.8 14.2 1.1 1 0 0 1 1 1 0 Methyltransferase domain ASD2 PF08687.11 CDJ67841.1 - 9.5 5.7 16.7 12 5.3 16.7 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Pro_isomerase PF00160.21 CDJ67842.1 - 6.1e-42 143.6 0.2 1.1e-41 142.8 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_16 PF13432.6 CDJ67842.1 - 1.2e-07 32.2 3.8 2.2e-07 31.4 3.8 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ67842.1 - 5.7e-07 29.1 1.2 0.0013 18.4 0.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.28 CDJ67842.1 - 4.7e-06 26.2 1.2 0.031 14.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ67842.1 - 6.7e-06 25.8 7.1 0.0049 16.9 0.2 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ67842.1 - 0.00011 22.7 2.8 0.036 14.9 0.7 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ67842.1 - 0.00025 21.0 1.1 0.3 11.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ67842.1 - 0.00048 20.3 0.3 0.1 13.0 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat Mgr1 PF08602.10 CDJ67842.1 - 0.13 11.0 2.7 0.29 9.9 1.2 1.9 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Utp11 PF03998.13 CDJ67842.1 - 0.18 11.7 12.8 0.35 10.8 12.5 1.6 1 1 1 2 2 2 0 Utp11 protein Pex14_N PF04695.13 CDJ67842.1 - 0.41 11.3 10.1 0.69 10.6 10.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EIF4E-T PF10477.9 CDJ67842.1 - 0.52 9.1 12.4 0.69 8.7 12.4 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Presenilin PF01080.17 CDJ67842.1 - 0.6 8.8 3.3 0.83 8.3 3.3 1.2 1 0 0 1 1 1 0 Presenilin MCU PF04678.13 CDJ67842.1 - 0.96 9.5 7.4 1 9.5 2.8 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Exonuc_VII_L PF02601.15 CDJ67842.1 - 1 8.9 12.2 0.96 9.0 9.3 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit FtsX_ECD PF18075.1 CDJ67842.1 - 1.2 9.8 10.3 2.8 8.6 8.8 2.1 2 0 0 2 2 2 0 FtsX extracellular domain UPF0449 PF15136.6 CDJ67842.1 - 1.6 9.2 17.1 0.84 10.1 12.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Jnk-SapK_ap_N PF09744.9 CDJ67842.1 - 4 7.6 21.4 1.1 9.5 16.9 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2203 PF09969.9 CDJ67842.1 - 4.1 8.1 9.6 32 5.2 6.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TFIIA PF03153.13 CDJ67842.1 - 5.2 7.0 25.4 8.2 6.3 25.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM222A PF15258.6 CDJ67842.1 - 7.8 5.5 23.3 10 5.1 23.3 1.1 1 0 0 1 1 1 0 Protein family of FAM222A CPBP PF02517.16 CDJ67843.1 - 6.5e-08 32.8 0.0 6.5e-08 32.8 0.0 2.9 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease Activator_LAG-3 PF11498.8 CDJ67843.1 - 8 5.3 22.7 16 4.3 22.7 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Bromodomain PF00439.25 CDJ67844.1 - 1.2e-18 67.0 0.1 2.5e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 Bromodomain DUF2722 PF10846.8 CDJ67844.1 - 0.00026 20.1 3.6 0.00026 20.1 3.6 6.8 5 2 2 7 7 7 2 Protein of unknown function (DUF2722) DoxX_3 PF13781.6 CDJ67846.1 - 0.095 13.3 0.5 0.15 12.7 0.5 1.3 1 0 0 1 1 1 0 DoxX-like family CDK2AP PF09806.9 CDJ67846.1 - 0.29 11.1 1.8 0.49 10.4 1.8 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2828 PF11443.8 CDJ67847.1 - 0.19 9.8 8.4 0.23 9.5 8.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PIP5K PF01504.18 CDJ67847.1 - 0.39 9.9 7.7 0.65 9.2 7.7 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF572 PF04502.13 CDJ67847.1 - 0.55 9.8 13.5 0.94 9.0 13.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) NFACT-C PF11923.8 CDJ67847.1 - 0.64 10.0 4.3 2.2 8.2 0.4 2.1 2 0 0 2 2 2 0 NFACT protein C-terminal domain MAS20 PF02064.15 CDJ67847.1 - 0.94 9.6 14.3 1.6 8.8 1.0 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor Presenilin PF01080.17 CDJ67847.1 - 1 8.1 16.2 1.6 7.4 16.2 1.3 1 0 0 1 1 1 0 Presenilin DUF4064 PF13273.6 CDJ67847.1 - 1.1 9.5 5.1 13 6.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) SR-25 PF10500.9 CDJ67847.1 - 1.5 8.4 23.9 5.2 6.6 23.9 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PLA2_B PF01735.18 CDJ67847.1 - 2.5 6.4 6.9 1.4 7.2 0.5 2.0 1 1 1 2 2 2 0 Lysophospholipase catalytic domain RuvC_III PF18541.1 CDJ67847.1 - 3.1 7.7 10.4 4.6 7.2 3.8 2.1 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 Neur_chan_memb PF02932.16 CDJ67847.1 - 3.9 7.5 12.6 5.7 6.9 12.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 CDJ67847.1 - 5.1 5.9 48.1 0.36 9.7 15.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SprA-related PF12118.8 CDJ67848.1 - 0.0018 17.5 7.2 0.0018 17.5 7.2 4.8 3 2 2 5 5 5 1 SprA-related family MMU163 PF17119.5 CDJ67848.1 - 0.0077 15.4 1.0 0.0077 15.4 1.0 4.2 3 1 2 5 5 5 1 Mitochondrial protein up-regulated during meiosis VPDSG-CTERM PF18205.1 CDJ67848.1 - 4.7 7.1 8.2 23 4.9 8.2 2.3 1 0 0 1 1 1 0 VPDSG-CTERM motif CobS PF02654.15 CDJ67849.1 - 0.00093 19.4 0.4 0.00093 19.4 0.4 2.1 2 0 0 2 2 2 1 Cobalamin-5-phosphate synthase DUF2207 PF09972.9 CDJ67849.1 - 0.12 11.1 0.5 6.9 5.3 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) BatD PF13584.6 CDJ67849.1 - 0.2 10.4 0.2 0.56 8.9 0.2 1.7 1 1 0 1 1 1 0 Oxygen tolerance DUF898 PF05987.13 CDJ67849.1 - 3.2 6.7 8.3 1.2 8.2 5.0 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) IBN_N PF03810.19 CDJ67850.1 - 3.7e-06 26.7 0.9 4.8e-05 23.2 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.22 CDJ67850.1 - 0.0019 18.3 7.5 4.4 7.8 0.0 4.7 5 0 0 5 5 5 3 HEAT repeat Cohesin_HEAT PF12765.7 CDJ67850.1 - 0.13 12.6 0.1 9.2 6.7 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 CDJ67850.1 - 8.4 7.0 9.7 7.2 7.2 0.1 4.0 3 1 1 4 4 4 0 HEAT-like repeat Peptidase_S8 PF00082.22 CDJ67851.1 - 3.5e-16 59.3 0.1 3.7e-15 56.0 0.1 2.1 1 1 0 1 1 1 1 Subtilase family TFIIA PF03153.13 CDJ67851.1 - 0.0002 21.5 7.2 0.00022 21.3 7.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit OATP PF03137.20 CDJ67851.1 - 0.0023 16.3 0.0 0.0028 16.0 0.0 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Zn_peptidase PF04228.13 CDJ67851.1 - 0.0029 17.1 0.8 0.005 16.3 0.8 1.4 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase DUF2722 PF10846.8 CDJ67851.1 - 0.0076 15.3 14.5 0.011 14.8 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Cytochrom_B_N_2 PF13631.6 CDJ67851.1 - 0.019 15.0 0.1 0.052 13.6 0.1 1.7 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB SpoIIP PF07454.11 CDJ67851.1 - 0.025 14.0 0.8 0.034 13.6 0.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4834 PF16118.5 CDJ67851.1 - 0.026 15.5 3.3 0.042 14.8 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neuraminidase PF18413.1 CDJ67851.1 - 0.047 13.3 0.1 0.065 12.9 0.1 1.1 1 0 0 1 1 1 0 Neuraminidase-like domain Connexin PF00029.19 CDJ67851.1 - 0.097 12.4 0.7 0.14 11.9 0.7 1.1 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ67851.1 - 0.14 10.9 0.7 0.18 10.6 0.7 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ67851.1 - 0.15 11.0 4.2 0.19 10.7 4.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RED_N PF07808.13 CDJ67851.1 - 0.19 11.3 6.5 0.27 10.8 6.5 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DivIC PF04977.15 CDJ67851.1 - 0.32 10.8 14.1 0.53 10.1 14.1 1.3 1 0 0 1 1 1 0 Septum formation initiator Conotoxin PF02950.17 CDJ67851.1 - 0.46 11.5 1.6 0.82 10.7 1.6 1.4 1 0 0 1 1 1 0 Conotoxin Spt20 PF12090.8 CDJ67851.1 - 0.69 9.5 24.3 0.99 9.0 24.3 1.1 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ67851.1 - 0.8 9.6 6.7 1.1 9.2 6.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TMEM208_SND2 PF05620.11 CDJ67851.1 - 2.8 7.7 5.8 5.4 6.8 5.8 1.4 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Roughex PF06020.11 CDJ67851.1 - 2.8 7.0 6.0 3.6 6.6 6.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PAN_4 PF14295.6 CDJ67852.1 - 3.6e-12 46.0 9.6 8.1e-06 25.6 3.2 2.4 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 CDJ67852.1 - 4.2e-09 36.2 1.3 6.7e-05 22.8 0.2 2.8 2 0 0 2 2 2 2 PAN domain Integrase_H2C2 PF17921.1 CDJ67854.1 - 2.9e-16 59.3 2.3 8.5e-16 57.8 2.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ67854.1 - 3e-16 59.7 0.0 6.3e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ67854.1 - 0.00013 22.1 0.3 0.0003 21.0 0.3 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDJ67854.1 - 0.0028 17.4 1.2 0.18 11.6 0.1 2.8 3 0 0 3 3 3 1 Integrase core domain PPDK_N PF01326.19 CDJ67855.1 - 2.9e-15 56.4 0.0 3.4e-14 52.9 0.0 3.0 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain RPN13_C PF16550.5 CDJ67855.1 - 0.013 15.6 0.1 0.038 14.2 0.1 1.7 1 0 0 1 1 1 0 UCH-binding domain preATP-grasp_3 PF18301.1 CDJ67855.1 - 0.091 13.1 0.5 0.6 10.4 0.1 2.6 2 0 0 2 2 2 0 pre ATP-grasp 3 domain FXMR_C2 PF16098.5 CDJ67855.1 - 0.24 11.9 1.1 0.92 10.0 1.1 2.0 1 0 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 IBR PF01485.21 CDJ67856.1 - 1.3e-17 63.8 30.7 4.3e-10 39.7 4.2 3.8 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain Surface_antigen PF11054.8 CDJ67858.1 - 2.8e-57 194.2 3.8 3.5e-57 193.9 3.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen zinc_ribbon_10 PF10058.9 CDJ67858.1 - 0.056 13.2 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Isy1 PF06246.12 CDJ67859.1 - 2.2e-07 30.7 0.0 2.3e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family SpoIIIAH PF12685.7 CDJ67860.1 - 3.5 7.4 12.7 14 5.4 8.1 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Ribosomal_S5 PF00333.20 CDJ67861.1 - 2.8e-13 49.6 0.4 1.2e-12 47.6 0.4 2.1 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain dsrm PF00035.26 CDJ67861.1 - 0.029 15.1 0.0 0.22 12.2 0.0 2.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif PRP38 PF03371.15 CDJ67862.1 - 3.7e-52 176.7 0.1 5.8e-52 176.1 0.1 1.3 1 0 0 1 1 1 1 PRP38 family PCB_OB PF17092.5 CDJ67862.1 - 0.016 16.0 3.0 0.093 13.5 0.0 3.3 3 1 0 3 3 3 0 Penicillin-binding protein OB-like domain RMI2 PF16100.5 CDJ67862.1 - 0.018 14.9 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 0 RecQ-mediated genome instability protein 2 S1 PF00575.23 CDJ67862.1 - 0.063 13.6 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 S1 RNA binding domain DUF4551 PF15087.6 CDJ67862.1 - 8.8 5.0 15.8 14 4.3 15.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) IMCp PF12314.8 CDJ67863.1 - 1.3e-17 63.9 67.8 1.8e-11 44.1 28.6 5.7 1 1 4 5 5 5 3 Inner membrane complex protein N2227 PF07942.12 CDJ67865.1 - 8.9e-77 257.9 0.0 1.1e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 CDJ67865.1 - 0.0087 16.7 0.0 0.045 14.4 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain SUIM_assoc PF16619.5 CDJ67867.1 - 1.8e-07 31.1 0.0 0.052 13.6 0.0 3.3 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 PurK_C PF17769.1 CDJ67867.1 - 0.19 11.4 0.3 0.35 10.6 0.3 1.4 1 0 0 1 1 1 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain EURL PF06937.11 CDJ67867.1 - 0.43 9.9 1.5 0.73 9.2 1.5 1.2 1 0 0 1 1 1 0 EURL protein SNF2_N PF00176.23 CDJ67869.1 - 4.4e-19 68.4 0.2 1.2e-09 37.4 0.0 2.8 1 1 1 2 2 2 2 SNF2 family N-terminal domain TFIIA PF03153.13 CDJ67869.1 - 0.00021 21.4 7.0 0.00021 21.4 7.0 6.3 2 2 3 6 6 6 1 Transcription factor IIA, alpha/beta subunit DUF2589 PF11655.8 CDJ67869.1 - 0.0026 18.1 0.4 0.0026 18.1 0.4 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF2589) Spt20 PF12090.8 CDJ67869.1 - 0.0036 16.9 5.0 0.0036 16.9 5.0 7.2 7 1 1 8 8 8 4 Spt20 family Helicase_C PF00271.31 CDJ67869.1 - 0.0068 16.7 0.2 0.049 14.0 0.1 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain TFIIA PF03153.13 CDJ67870.1 - 0.15 12.0 13.1 0.22 11.5 13.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAM35 PF10806.8 CDJ67870.1 - 3.2 8.0 5.7 2.3 8.5 1.0 2.6 1 1 0 2 2 2 0 SAM35, subunit of SAM coomplex Spt20 PF12090.8 CDJ67871.1 - 0.013 15.1 8.4 0.021 14.4 8.4 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ67871.1 - 0.79 9.6 21.9 0.074 13.0 16.1 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LNS2 PF08235.13 CDJ67873.1 - 1.4e-17 63.9 0.0 1.9e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_mid PF16876.5 CDJ67873.1 - 9.7e-16 57.8 0.0 1.5e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Asp_protease_2 PF13650.6 CDJ67874.1 - 1.5e-09 38.4 0.0 3.1e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDJ67874.1 - 4.2e-09 36.3 0.0 1.1e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ67874.1 - 6.2e-09 36.3 0.0 1.1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ67874.1 - 0.00051 19.8 0.0 0.00084 19.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ67874.1 - 0.0083 16.4 0.0 0.02 15.2 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease CCDC142 PF14923.6 CDJ67876.1 - 0.34 9.6 3.8 0.46 9.2 3.8 1.1 1 0 0 1 1 1 0 Coiled-coil protein 142 Ashwin PF15323.6 CDJ67876.1 - 3 7.8 6.7 4.1 7.4 6.7 1.1 1 0 0 1 1 1 0 Developmental protein Apt1 PF10351.9 CDJ67876.1 - 3.2 6.5 5.6 3.8 6.3 5.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain RT_RNaseH_2 PF17919.1 CDJ67877.1 - 9.3e-30 102.6 0.2 1.6e-29 101.9 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ67877.1 - 3.5e-27 94.7 0.1 5.6e-27 94.1 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FAM92 PF06730.11 CDJ67877.1 - 0.026 14.0 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 FAM92 protein RVT_3 PF13456.6 CDJ67877.1 - 0.029 14.2 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like zf-CCCH PF00642.24 CDJ67878.1 - 3.9e-09 36.2 28.0 0.0046 16.8 7.3 3.9 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDJ67878.1 - 3.1e-07 31.1 18.9 0.005 17.5 3.0 3.1 1 1 2 3 3 3 3 Torus domain zf_CCCH_4 PF18345.1 CDJ67878.1 - 1.6e-05 24.8 30.9 0.0044 17.0 7.1 4.2 4 0 0 4 4 4 3 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ67878.1 - 0.00025 20.8 23.6 0.073 12.9 3.3 4.0 3 1 0 3 3 3 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CDJ67878.1 - 0.025 14.8 11.2 0.27 11.5 5.2 2.2 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDJ67878.1 - 0.045 14.2 13.6 0.29 11.7 1.8 3.3 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger SUIM_assoc PF16619.5 CDJ67880.1 - 0.00092 19.2 22.1 0.0033 17.4 10.1 2.7 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Ndc1_Nup PF09531.10 CDJ67880.1 - 0.0081 14.9 1.1 0.0089 14.8 1.1 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup IMUP PF15761.5 CDJ67880.1 - 0.017 15.8 4.5 0.017 15.8 4.5 2.0 2 0 0 2 2 1 0 Immortalisation up-regulated protein Dehydrin PF00257.19 CDJ67880.1 - 0.034 14.7 4.9 0.069 13.7 4.9 1.5 1 0 0 1 1 1 0 Dehydrin MAM33 PF02330.16 CDJ67880.1 - 0.035 14.1 1.3 0.049 13.6 1.3 1.1 1 0 0 1 1 1 0 Mitochondrial glycoprotein Tir_receptor_N PF07490.11 CDJ67880.1 - 0.045 13.6 0.4 0.067 13.0 0.4 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Rtf2 PF04641.12 CDJ67880.1 - 0.066 12.6 2.5 0.089 12.1 2.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger ATP_bind_3 PF01171.20 CDJ67880.1 - 0.08 12.7 0.0 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 PP-loop family NEMP PF10225.9 CDJ67880.1 - 0.13 11.9 1.4 0.22 11.2 1.4 1.3 1 0 0 1 1 1 0 NEMP family Ctr PF04145.15 CDJ67880.1 - 0.13 12.8 1.0 0.22 12.1 1.0 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Paf1 PF03985.13 CDJ67880.1 - 0.17 10.9 4.3 0.26 10.2 4.3 1.2 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 CDJ67880.1 - 0.33 9.7 5.7 0.44 9.2 5.7 1.1 1 0 0 1 1 1 0 Presenilin ANAPC_CDC26 PF10471.9 CDJ67880.1 - 0.38 11.6 23.5 0.84 10.5 13.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF3381 PF11861.8 CDJ67880.1 - 0.41 10.4 5.3 0.65 9.8 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Sec3_C PF09763.9 CDJ67880.1 - 0.42 8.9 4.9 0.55 8.6 4.9 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF4834 PF16118.5 CDJ67880.1 - 0.47 11.4 7.2 0.13 13.2 2.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SR-25 PF10500.9 CDJ67880.1 - 0.48 10.0 18.5 0.85 9.2 18.5 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 CDJ67880.1 - 0.58 7.2 4.8 0.72 6.9 4.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 CDJ67880.1 - 0.65 10.0 2.7 0.94 9.5 2.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4228 PF14009.6 CDJ67880.1 - 1.9 8.8 6.8 3 8.2 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) EBP50_C PF09007.11 CDJ67880.1 - 2 9.4 11.0 3.3 8.7 11.0 1.3 1 0 0 1 1 1 0 EBP50, C-terminal CDK2AP PF09806.9 CDJ67880.1 - 3.4 7.7 11.4 5.1 7.1 11.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2722 PF10846.8 CDJ67880.1 - 3.5 6.5 18.9 1.1 8.1 13.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF2681 PF10883.8 CDJ67880.1 - 3.5 8.1 14.1 0.65 10.4 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Roughex PF06020.11 CDJ67880.1 - 4.4 6.3 14.3 7.3 5.6 14.2 1.4 1 1 0 1 1 1 0 Drosophila roughex protein IMUP PF15761.5 CDJ67882.1 - 0.048 14.4 3.8 0.086 13.5 3.8 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein MAGE_N PF12440.8 CDJ67882.1 - 0.048 14.3 3.0 0.048 14.3 3.0 2.4 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal SR-25 PF10500.9 CDJ67882.1 - 0.075 12.6 4.5 0.095 12.3 4.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ67882.1 - 0.15 12.4 6.2 0.2 11.9 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Helicase_C PF00271.31 CDJ67883.1 - 2.3e-07 31.1 0.0 2.3e-07 31.1 0.0 2.4 3 1 0 3 3 3 1 Helicase conserved C-terminal domain Endostatin PF06482.11 CDJ67883.1 - 0.87 9.0 21.7 0.8 9.1 15.2 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin DUF572 PF04502.13 CDJ67883.1 - 1.4 8.5 25.8 1.1 8.8 19.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) PAT1 PF09770.9 CDJ67883.1 - 5.4 5.2 48.0 2.1 6.5 38.2 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 VIR_N PF15912.5 CDJ67883.1 - 7.4 6.1 21.4 2.1 7.9 13.7 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal Lin-8 PF03353.15 CDJ67883.1 - 9.5 5.7 31.5 4.9 6.6 0.5 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ67884.1 - 0.26 10.9 5.3 0.37 10.4 5.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2967 PF11179.8 CDJ67884.1 - 0.38 8.8 5.3 0.52 8.3 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF1676 PF07898.13 CDJ67885.1 - 0.46 10.5 9.5 0.62 10.1 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) RIFIN PF02009.16 CDJ67885.1 - 1.4 8.7 21.1 1.6 8.5 21.1 1.0 1 0 0 1 1 1 0 Rifin Retrotrans_gag PF03732.17 CDJ67887.1 - 2e-05 24.8 0.1 3e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein AIM5 PF17050.5 CDJ67887.1 - 0.018 15.9 0.1 0.03 15.1 0.1 1.4 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 S6PP PF05116.13 CDJ67889.1 - 0.013 15.1 0.2 0.067 12.7 0.5 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase DUF3458_C PF17432.2 CDJ67892.1 - 1.5e-76 257.8 14.9 1.5e-76 257.8 14.9 8.5 6 3 2 9 9 9 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 CDJ67892.1 - 4.4e-15 55.9 5.1 2.6e-12 46.8 0.0 3.2 2 1 1 3 3 3 2 Peptidase family M1 domain NUC173 PF08161.12 CDJ67892.1 - 2.5e-14 53.4 0.2 2.5e-14 53.4 0.2 5.3 6 1 0 6 6 6 1 NUC173 domain DUF3458 PF11940.8 CDJ67892.1 - 4.2e-11 43.1 0.0 4.2e-11 43.1 0.0 6.8 7 1 0 7 7 7 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 CDJ67892.1 - 2.5e-09 37.6 0.0 2.5e-09 37.6 0.0 2.6 3 0 0 3 3 3 1 Peptidase M1 N-terminal domain DUF2722 PF10846.8 CDJ67892.1 - 0.00053 19.0 13.7 0.00053 19.0 13.7 12.7 11 3 1 12 12 12 4 Protein of unknown function (DUF2722) HALZ PF02183.18 CDJ67894.1 - 0.083 13.1 4.9 0.17 12.2 0.2 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF4047 PF13256.6 CDJ67894.1 - 0.15 12.3 1.0 0.21 11.8 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF1664 PF07889.12 CDJ67894.1 - 0.28 11.2 0.7 0.38 10.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 CDJ67894.1 - 9.8 6.0 7.9 7.3 6.4 0.9 2.3 1 1 1 2 2 2 0 Septum formation initiator MAS20 PF02064.15 CDJ67895.1 - 0.00079 19.5 0.5 0.00079 19.5 0.5 3.2 3 0 0 3 3 3 1 MAS20 protein import receptor RskA PF10099.9 CDJ67895.1 - 0.005 17.2 12.3 0.005 17.2 12.3 4.0 1 1 2 3 3 2 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ67895.1 - 0.0062 15.5 2.0 0.0062 15.5 2.0 3.1 2 1 0 3 3 1 1 Protein of unknown function (DUF2722) ArsP_2 PF11449.8 CDJ67895.1 - 0.011 14.9 0.4 0.011 14.9 0.4 1.8 2 0 0 2 2 2 0 Putative, 10TM heavy-metal exporter 7tm_1 PF00001.21 CDJ67895.1 - 0.018 14.3 0.1 0.018 14.3 0.1 1.7 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) ANAPC_CDC26 PF10471.9 CDJ67895.1 - 0.037 14.9 8.3 0.037 14.9 8.3 3.4 2 1 0 3 3 2 0 Anaphase-promoting complex APC subunit CDC26 DcuC PF03606.15 CDJ67895.1 - 0.051 12.0 1.6 0.14 10.6 0.1 2.0 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier Connexin PF00029.19 CDJ67895.1 - 0.091 12.5 0.0 0.091 12.5 0.0 2.5 2 1 0 2 2 1 0 Connexin Kei1 PF08552.11 CDJ67895.1 - 0.1 12.4 0.1 0.1 12.4 0.1 3.0 2 1 0 2 2 1 0 Inositolphosphorylceramide synthase subunit Kei1 CLN3 PF02487.17 CDJ67895.1 - 0.12 11.4 0.1 0.12 11.4 0.1 2.5 2 1 0 2 2 1 0 CLN3 protein MLANA PF14991.6 CDJ67895.1 - 0.12 12.6 1.0 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein melan-A DUF4179 PF13786.6 CDJ67895.1 - 0.17 12.4 7.7 0.23 11.9 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DUF4834 PF16118.5 CDJ67895.1 - 0.18 12.8 0.3 0.18 12.8 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Rxt3 PF08642.10 CDJ67895.1 - 0.21 12.4 5.3 7.8 7.3 0.1 2.9 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 OATP PF03137.20 CDJ67895.1 - 0.49 8.6 1.9 3.9 5.6 0.1 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EphA2_TM PF14575.6 CDJ67895.1 - 0.7 10.8 0.1 0.7 10.8 0.1 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain NEMP PF10225.9 CDJ67895.1 - 0.78 9.4 5.3 1 8.9 1.1 2.2 2 0 0 2 2 2 0 NEMP family SID-1_RNA_chan PF13965.6 CDJ67895.1 - 2.7 6.3 3.9 1.7 7.0 0.1 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 CDJ67895.1 - 4 6.1 19.3 6.2 5.5 0.1 2.3 2 0 0 2 2 2 0 Presenilin FHIPEP PF00771.20 CDJ67895.1 - 4.9 5.5 12.0 0.2 10.1 0.8 2.2 2 0 0 2 2 2 0 FHIPEP family Ctr PF04145.15 CDJ67895.1 - 5.1 7.7 0.0 5.1 7.7 0.0 2.8 2 1 0 2 2 1 0 Ctr copper transporter family FAM176 PF14851.6 CDJ67895.1 - 5.6 6.6 10.2 9.8 5.8 0.0 2.9 3 0 0 3 3 3 0 FAM176 family rve PF00665.26 CDJ67896.1 - 0.001 19.3 0.0 0.0011 19.2 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ67897.1 - 4.5e-15 55.3 0.0 1e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-RanBP PF00641.18 CDJ67898.1 - 0.00055 19.2 14.2 0.069 12.5 5.5 2.7 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 CDJ67898.1 - 0.016 15.2 13.4 0.059 13.4 0.6 2.6 2 0 0 2 2 2 0 Double zinc ribbon FAM104 PF15434.6 CDJ67898.1 - 3.1 8.4 58.7 11 6.7 5.8 5.2 2 1 1 3 3 3 0 Family 104 Tnp_zf-ribbon_2 PF13842.6 CDJ67898.1 - 6.5 7.7 11.8 17 6.3 3.2 2.7 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon EF-hand_1 PF00036.32 CDJ67899.1 - 5.7e-09 34.9 1.1 0.00084 18.7 0.3 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CDJ67899.1 - 1.1e-08 34.4 0.7 0.0044 16.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CDJ67899.1 - 7.8e-08 32.7 0.0 0.012 16.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ67899.1 - 4.1e-07 29.2 1.1 0.024 14.2 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ67899.1 - 0.00014 21.7 1.5 0.11 12.3 0.2 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 CDJ67899.1 - 0.0033 17.7 0.0 0.17 12.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain DUF2057 PF09829.9 CDJ67899.1 - 0.57 10.3 2.9 0.76 9.9 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Pkinase PF00069.25 CDJ67901.1 - 1e-08 34.9 0.1 2.5e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain DUF2722 PF10846.8 CDJ67901.1 - 0.002 17.2 32.4 0.064 12.2 1.4 4.3 4 0 0 4 4 4 4 Protein of unknown function (DUF2722) Pkinase_Tyr PF07714.17 CDJ67901.1 - 0.0037 16.6 0.0 0.0073 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AUX_IAA PF02309.16 CDJ67901.1 - 0.1 12.4 0.2 6 6.6 0.0 3.2 3 2 0 3 3 3 0 AUX/IAA family Spt20 PF12090.8 CDJ67901.1 - 0.82 9.2 55.5 0.061 12.9 4.5 4.2 4 0 0 4 4 4 0 Spt20 family TFIIA PF03153.13 CDJ67901.1 - 2.7 7.9 58.9 0.3 11.0 4.0 4.1 4 0 0 4 4 4 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CDJ67902.1 - 9.4e-15 54.7 0.0 3.9e-10 39.5 0.0 3.7 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ67902.1 - 3.1e-08 33.2 0.0 7.3e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase SUIM_assoc PF16619.5 CDJ67902.1 - 3.9e-05 23.6 4.4 3.9e-05 23.6 4.4 6.9 5 2 0 5 5 5 3 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CDJ67902.1 - 0.00078 20.0 2.1 0.00078 20.0 2.1 7.9 5 2 2 7 7 7 2 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ67902.1 - 0.0067 16.1 3.3 0.0067 16.1 3.3 5.1 4 1 0 4 4 4 2 Spt20 family Presenilin PF01080.17 CDJ67902.1 - 0.0079 15.0 28.6 0.023 13.5 0.0 3.1 3 0 0 3 3 3 2 Presenilin Pkinase_fungal PF17667.1 CDJ67902.1 - 4 6.1 15.4 0.021 13.6 4.5 2.4 2 1 0 2 2 2 0 Fungal protein kinase SUIM_assoc PF16619.5 CDJ67903.1 - 0.046 13.8 3.7 1.5 9.0 1.1 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Dzip-like_N PF13815.6 CDJ67903.1 - 0.4 10.7 4.4 0.83 9.6 4.4 1.4 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Spt20 PF12090.8 CDJ67906.1 - 0.29 10.7 9.1 0.4 10.3 9.1 1.2 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ67906.1 - 6 5.5 5.7 6.3 5.5 5.7 1.0 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 CDJ67908.1 - 0.58 8.6 36.5 0.073 11.6 10.7 2.4 2 0 0 2 2 2 0 Macoilin family MRJP PF03022.16 CDJ67909.1 - 0.039 13.3 2.6 0.059 12.7 2.6 1.3 1 0 0 1 1 1 0 Major royal jelly protein DEAD PF00270.29 CDJ67910.1 - 3.8e-16 59.4 9.1 3.8e-16 59.4 9.1 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ67910.1 - 2.2e-12 47.3 0.0 2.2e-12 47.3 0.0 3.7 3 1 1 4 4 4 1 Helicase conserved C-terminal domain SARAF PF06682.12 CDJ67910.1 - 0.0019 17.9 6.3 0.0019 17.9 6.3 5.1 2 2 3 5 5 5 1 SOCE-associated regulatory factor of calcium homoeostasis AAA PF00004.29 CDJ67910.1 - 0.1 13.0 1.3 8.7 6.8 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ASD2 PF08687.11 CDJ67911.1 - 0.012 15.2 7.7 0.015 14.9 7.7 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Methyltr_RsmB-F PF01189.17 CDJ67911.1 - 0.038 13.6 0.8 0.047 13.3 0.8 1.1 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F JUPITER PF17054.5 CDJ67911.1 - 0.079 12.4 3.1 0.091 12.2 3.1 1.0 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter PNISR PF15996.5 CDJ67911.1 - 0.51 10.6 10.7 0.58 10.4 10.7 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Med15 PF09606.10 CDJ67911.1 - 0.62 8.7 28.3 0.68 8.6 28.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.9 CDJ67911.1 - 0.66 10.2 25.0 1.9 8.7 11.9 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ67911.1 - 0.78 9.7 30.7 1 9.3 30.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 CDJ67911.1 - 1.3 9.0 5.6 1.5 8.8 5.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF3551 PF12071.8 CDJ67911.1 - 1.4 9.0 13.7 2.1 8.4 13.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3551) Senescence_reg PF04520.13 CDJ67911.1 - 1.9 9.3 10.9 2.7 8.8 10.9 1.3 1 0 0 1 1 1 0 Senescence regulator Suf PF05843.14 CDJ67911.1 - 3.1 7.7 14.2 4 7.3 14.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ67911.1 - 4 7.4 7.6 4.6 7.2 7.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ67911.1 - 4.6 5.9 11.8 5.2 5.7 11.8 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ67911.1 - 6.6 6.5 8.3 8 6.2 8.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Surface_antigen PF11054.8 CDJ67912.1 - 5.1e-79 265.4 4.1 7e-79 264.9 4.1 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen SecY PF00344.20 CDJ67913.1 - 3.6e-72 243.2 13.9 4.5e-72 242.9 13.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CDJ67913.1 - 3e-17 62.1 0.8 7.1e-17 61.0 0.0 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p Chorion_2 PF03964.15 CDJ67913.1 - 0.065 14.1 0.1 0.23 12.3 0.1 1.9 1 0 0 1 1 1 0 Chorion family 2 QCR10 PF09796.9 CDJ67913.1 - 9.3 6.4 6.1 9.2 6.4 0.1 3.5 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) 14-3-3 PF00244.20 CDJ67914.1 - 1.1e-17 64.3 5.8 3.2e-16 59.5 2.8 4.1 4 1 0 4 4 4 2 14-3-3 protein YvrJ PF12841.7 CDJ67914.1 - 0.031 13.8 0.1 0.057 13.0 0.1 1.4 1 0 0 1 1 1 0 YvrJ protein family RAP1 PF07218.11 CDJ67914.1 - 0.68 8.1 3.3 0.89 7.8 3.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cyclin_C PF02984.19 CDJ67914.1 - 7.7 6.6 9.1 1.1 9.3 3.5 2.5 2 0 0 2 2 2 0 Cyclin, C-terminal domain PDEase_I PF00233.19 CDJ67915.1 - 2.5e-31 109.2 0.0 2.5e-31 109.2 0.0 4.9 3 1 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase RskA PF10099.9 CDJ67915.1 - 0.00026 21.4 12.3 0.00026 21.4 12.3 9.8 2 1 2 4 4 4 1 Anti-sigma-K factor rskA Caldesmon PF02029.15 CDJ67916.1 - 0.35 9.6 69.6 0.37 9.5 69.6 1.0 1 0 0 1 1 1 0 Caldesmon LAP1C PF05609.12 CDJ67916.1 - 0.97 8.4 68.4 1.2 8.1 68.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Utp14 PF04615.13 CDJ67916.1 - 3 6.3 66.2 3.7 6.0 66.2 1.0 1 0 0 1 1 1 0 Utp14 protein BAR_2 PF10455.9 CDJ67917.1 - 0.092 11.9 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking WD40 PF00400.32 CDJ67918.1 - 2.7e-24 85.0 0.0 9e-06 26.3 0.1 9.1 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ67918.1 - 5.7e-05 23.3 8.5 5.9 7.3 0.0 6.7 7 1 1 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ67918.1 - 0.00011 21.2 1.5 0.85 8.5 0.2 3.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TMEM51 PF15345.6 CDJ67918.1 - 0.00013 21.9 2.1 0.00013 21.9 2.1 7.8 8 0 0 8 8 8 2 Transmembrane protein 51 RskA PF10099.9 CDJ67918.1 - 0.0021 18.4 3.5 0.0021 18.4 3.5 10.9 4 1 4 9 9 9 3 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ67918.1 - 0.0066 16.1 7.9 0.0066 16.1 7.9 7.3 8 1 0 8 8 8 2 Nuclear RNA-splicing-associated protein DUF4483 PF14825.6 CDJ67919.1 - 0.068 12.9 10.0 0.68 9.7 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) TFIIA PF03153.13 CDJ67919.1 - 0.1 12.6 24.0 0.12 12.4 24.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 CDJ67919.1 - 2.7 8.2 15.0 3.3 7.9 15.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF45 PF01863.17 CDJ67919.1 - 3.2 7.8 9.2 3.7 7.5 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 ANAPC_CDC26 PF10471.9 CDJ67919.1 - 6.8 7.6 32.2 0.3 12.0 7.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4050 PF13259.6 CDJ67920.1 - 0.31 11.3 1.8 0.43 10.9 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) RskA PF10099.9 CDJ67921.1 - 1.8 8.8 20.1 2.2 8.5 20.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Hc1 PF07432.13 CDJ67921.1 - 2.2 8.7 22.3 3 8.2 22.3 1.1 1 0 0 1 1 1 0 Histone H1-like protein Hc1 SUIM_assoc PF16619.5 CDJ67922.1 - 0.018 15.1 4.7 0.018 15.1 4.7 6.5 5 1 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 NUC130_3NT PF08158.12 CDJ67923.1 - 0.048 14.0 0.1 0.28 11.5 0.1 2.1 2 0 0 2 2 2 0 NUC130/3NT domain DivIC PF04977.15 CDJ67924.1 - 0.31 10.8 4.5 0.6 9.9 4.5 1.4 1 0 0 1 1 1 0 Septum formation initiator PV-1 PF06637.11 CDJ67924.1 - 0.46 9.2 7.3 0.54 9.0 7.3 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Nop53 PF07767.11 CDJ67924.1 - 0.63 9.4 9.8 0.79 9.1 9.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cyt-b5 PF00173.28 CDJ67925.1 - 4.3e-17 62.0 0.0 6.7e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4598 PF15370.6 CDJ67925.1 - 0.17 12.4 0.1 3.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) TFIIA PF03153.13 CDJ67925.1 - 2.3 8.1 7.2 2.7 7.9 7.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ67925.1 - 5.8 4.9 13.6 1.3 7.0 2.9 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DSPc PF00782.20 CDJ67926.1 - 6e-12 45.5 1.4 8.9e-10 38.5 0.6 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Macoilin PF09726.9 CDJ67926.1 - 0.0055 15.3 27.0 0.051 12.1 18.5 2.4 2 0 0 2 2 2 2 Macoilin family Ribosomal_60s PF00428.19 CDJ67926.1 - 0.0099 16.4 17.7 0.0099 16.4 17.7 5.5 4 1 0 4 4 4 1 60s Acidic ribosomal protein Y_phosphatase PF00102.27 CDJ67926.1 - 0.086 12.4 0.1 0.086 12.4 0.1 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase SRP-alpha_N PF04086.13 CDJ67926.1 - 1.3 8.9 32.4 4.3 7.2 32.4 1.9 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RskA PF10099.9 CDJ67927.1 - 0.0038 17.6 0.4 0.0038 17.6 0.4 2.6 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF2508 PF10704.9 CDJ67927.1 - 0.07 13.3 6.9 0.16 12.2 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DUF2065 PF09838.9 CDJ67927.1 - 0.098 12.7 0.2 0.098 12.7 0.2 2.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2065) DUF2207 PF09972.9 CDJ67927.1 - 0.1 11.4 0.1 0.24 10.1 0.1 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) PhdYeFM_antitox PF02604.19 CDJ67927.1 - 0.16 11.8 2.1 0.24 11.2 0.1 2.2 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Nuc_deoxyrib_tr PF05014.15 CDJ67927.1 - 0.68 10.0 2.8 0.96 9.5 0.1 2.4 3 0 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase DUF243 PF03103.17 CDJ67927.1 - 0.88 9.9 9.0 0.31 11.4 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF243) DUF4834 PF16118.5 CDJ67927.1 - 4.4 8.3 7.0 0.9 10.5 0.6 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ67927.1 - 6.6 6.3 23.1 7.8 6.0 14.4 2.2 2 0 0 2 2 2 0 Spt20 family DUF2339 PF10101.9 CDJ67928.1 - 1.1e-06 27.5 8.8 1.4e-06 27.2 8.8 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) GAGA_bind PF06217.12 CDJ67928.1 - 0.0047 17.2 23.1 0.0047 17.2 23.1 2.3 2 0 0 2 2 2 1 GAGA binding protein-like family SUIM_assoc PF16619.5 CDJ67928.1 - 0.027 14.5 7.3 0.027 14.5 7.3 8.2 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pns11_12 PF17464.2 CDJ67929.1 - 1.5 8.5 17.2 0.041 13.6 9.7 1.9 2 0 0 2 2 2 0 Non-structural protein 11 and 12 SR-25 PF10500.9 CDJ67929.1 - 1.6 8.3 63.1 14 5.2 14.7 3.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Catalase PF00199.19 CDJ67931.1 - 2.1e-192 639.3 0.8 2.4e-192 639.2 0.0 1.5 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.12 CDJ67931.1 - 2.3e-09 37.3 0.0 6.9e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF755 PF05501.11 CDJ67931.1 - 0.00012 22.3 33.3 0.00012 22.3 33.3 5.6 5 1 0 5 5 5 1 Domain of unknown function (DUF755) SPX PF03105.19 CDJ67931.1 - 0.0002 21.4 5.0 0.0002 21.4 5.0 4.1 2 1 0 2 2 2 1 SPX domain Mem_trans PF03547.18 CDJ67931.1 - 0.0019 16.7 0.2 0.0043 15.5 0.2 1.6 1 0 0 1 1 1 1 Membrane transport protein SAGA-Tad1 PF12767.7 CDJ67931.1 - 4 7.1 29.7 0.13 12.0 10.8 3.3 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit TGase_elicitor PF16683.5 CDJ67931.1 - 4.7 5.9 6.1 8.6 5.0 6.1 1.4 1 0 0 1 1 1 0 Transglutaminase elicitor PAT1 PF09770.9 CDJ67932.1 - 0.0065 14.8 41.7 0.0077 14.6 41.7 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.19 CDJ67932.1 - 0.77 10.4 19.6 0.14 12.8 9.5 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Asp-B-Hydro_N PF05279.11 CDJ67932.1 - 6.1 6.8 17.4 10 6.1 17.4 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3824 PF12868.7 CDJ67933.1 - 0.02 15.5 9.4 0.02 15.5 9.4 2.1 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) BAF1_ABF1 PF04684.13 CDJ67933.1 - 2.5 7.1 13.0 3 6.8 13.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MAT1 PF06391.13 CDJ67933.1 - 4.1 7.2 10.5 4.9 6.9 10.5 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Lin-8 PF03353.15 CDJ67933.1 - 5.8 6.4 13.4 7.6 6.0 13.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist API5 PF05918.11 CDJ67933.1 - 8.1 5.1 10.1 9.9 4.8 10.1 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Peptidase_S49_N PF08496.10 CDJ67934.1 - 2.2 8.3 10.1 0.72 9.9 3.2 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Presenilin PF01080.17 CDJ67934.1 - 3.4 6.4 7.8 3.8 6.2 7.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 CDJ67934.1 - 4.9 4.9 27.6 5.4 4.8 27.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) O-antigen_lig PF13425.6 CDJ67934.1 - 6.3 5.5 5.5 6.8 5.4 5.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SR-25 PF10500.9 CDJ67935.1 - 0.0028 17.3 10.7 0.0028 17.3 10.7 3.2 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 CDJ67936.1 - 5.6e-23 81.7 2.0 9.3e-12 44.9 0.0 3.5 2 1 1 4 4 3 2 Protein kinase domain Pkinase_fungal PF17667.1 CDJ67936.1 - 0.00091 18.1 0.2 0.00091 18.1 0.2 3.1 3 0 0 3 3 3 1 Fungal protein kinase MID_MedPIWI PF18296.1 CDJ67936.1 - 0.0011 18.8 2.7 0.0011 18.8 2.7 4.2 3 1 1 4 4 4 1 MID domain of medPIWI Pkinase_Tyr PF07714.17 CDJ67936.1 - 0.0014 17.9 0.7 0.92 8.7 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Ribosomal_60s PF00428.19 CDJ67936.1 - 0.045 14.3 1.2 0.045 14.3 1.2 6.6 3 1 3 6 6 5 0 60s Acidic ribosomal protein Band_3_cyto PF07565.13 CDJ67936.1 - 0.12 12.2 18.8 0.018 14.9 3.4 3.4 3 0 0 3 3 3 0 Band 3 cytoplasmic domain ABC2_membrane_2 PF12679.7 CDJ67936.1 - 0.57 9.4 3.2 1.6 7.9 3.2 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein FliP PF00813.20 CDJ67936.1 - 0.59 10.0 3.8 1.1 9.1 3.8 1.4 1 0 0 1 1 1 0 FliP family Plasmodium_Vir PF05795.11 CDJ67936.1 - 0.79 9.1 23.9 0.4 10.1 1.7 3.1 3 0 0 3 3 3 0 Plasmodium vivax Vir protein Piezo_RRas_bdg PF12166.8 CDJ67936.1 - 0.8 8.9 6.7 0.19 11.0 2.4 2.0 2 0 0 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain Zip PF02535.22 CDJ67936.1 - 0.85 8.8 15.3 0.24 10.6 0.2 3.3 3 0 0 3 3 3 0 ZIP Zinc transporter DUF4446 PF14584.6 CDJ67936.1 - 4.7 7.2 7.1 10 6.1 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) PTPRCAP PF15713.5 CDJ67936.1 - 4.8 7.4 45.6 0.18 12.1 13.9 4.3 4 0 0 4 4 4 0 Protein tyrosine phosphatase receptor type C-associated Apt1 PF10351.9 CDJ67936.1 - 6.5 5.5 40.0 0.72 8.6 1.9 3.2 3 0 0 3 3 3 0 Golgi-body localisation protein domain SpoIIP PF07454.11 CDJ67936.1 - 9.6 5.6 25.0 0.35 10.3 11.4 2.9 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) Spt20 PF12090.8 CDJ67937.1 - 0.011 15.3 5.0 0.016 14.9 5.0 1.4 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ67937.1 - 0.036 14.1 12.1 0.036 14.1 12.1 2.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Ndc1_Nup PF09531.10 CDJ67937.1 - 0.066 11.9 6.6 0.072 11.8 6.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 CDJ67937.1 - 0.18 10.4 12.4 0.2 10.3 12.4 1.1 1 0 0 1 1 1 0 Hamartin protein Suf PF05843.14 CDJ67937.1 - 0.73 9.8 5.2 0.92 9.4 5.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RAP1 PF07218.11 CDJ67937.1 - 2.2 6.5 19.8 2.7 6.2 19.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2859 PF11072.8 CDJ67937.1 - 5 6.9 6.7 1 9.1 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2859) WW PF00397.26 CDJ67938.1 - 1.2e-05 25.2 2.4 1.2e-05 25.2 2.4 1.8 2 0 0 2 2 2 1 WW domain Hamartin PF04388.12 CDJ67939.1 - 0.5 9.0 25.4 0.57 8.8 25.4 1.0 1 0 0 1 1 1 0 Hamartin protein PRCC PF10253.9 CDJ67939.1 - 0.89 10.3 32.1 1.1 10.0 32.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Retrotrans_gag PF03732.17 CDJ67940.1 - 0.012 15.9 0.0 0.056 13.7 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein Fer2_BFD PF04324.15 CDJ67940.1 - 0.14 12.5 0.4 0.35 11.3 0.4 1.6 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Utp14 PF04615.13 CDJ67941.1 - 4.2 5.8 88.5 1.7 7.1 61.6 2.2 2 0 0 2 2 2 0 Utp14 protein BaxI_1 PF12811.7 CDJ67942.1 - 0.0049 16.5 1.1 0.0059 16.2 1.1 1.0 1 0 0 1 1 1 1 Bax inhibitor 1 like Med26_C PF15693.5 CDJ67942.1 - 0.043 14.0 2.4 0.046 13.9 2.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal TFIIA PF03153.13 CDJ67942.1 - 0.073 13.1 16.6 0.086 12.8 16.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ67942.1 - 0.089 12.4 17.5 0.11 12.1 17.5 1.1 1 0 0 1 1 1 0 Spt20 family NST1 PF13945.6 CDJ67942.1 - 0.18 11.9 8.5 0.2 11.7 8.5 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator NUDE_C PF04880.13 CDJ67942.1 - 0.19 12.2 8.0 0.22 12.0 8.0 1.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region AOX PF01786.17 CDJ67942.1 - 0.25 10.9 5.6 0.31 10.6 5.6 1.1 1 0 0 1 1 1 0 Alternative oxidase Sporozoite_P67 PF05642.11 CDJ67942.1 - 0.29 9.2 4.4 0.31 9.1 4.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4647 PF15504.6 CDJ67942.1 - 0.32 10.1 5.4 0.32 10.1 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) RIFIN PF02009.16 CDJ67942.1 - 2.5 7.9 13.0 3.4 7.5 13.0 1.2 1 0 0 1 1 1 0 Rifin RLL PF10036.9 CDJ67942.1 - 3.4 7.4 12.6 4 7.2 12.6 1.1 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein DUF775 PF05603.12 CDJ67942.1 - 4 6.9 11.0 5 6.6 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Tic110 PF16940.5 CDJ67942.1 - 4 5.8 15.6 4.6 5.6 15.6 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter CDK2AP PF09806.9 CDJ67942.1 - 4.2 7.4 21.1 4.9 7.2 21.1 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Draxin PF15550.6 CDJ67942.1 - 4.2 7.1 8.1 4.9 6.9 8.1 1.1 1 0 0 1 1 1 0 Draxin BAT2_N PF07001.11 CDJ67942.1 - 4.7 7.6 17.0 5.6 7.4 17.0 1.1 1 0 0 1 1 1 0 BAT2 N-terminus Presenilin PF01080.17 CDJ67942.1 - 6.7 5.4 8.6 7.3 5.2 8.6 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ67942.1 - 8.3 5.0 11.3 9 4.8 11.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EBP50_C PF09007.11 CDJ67942.1 - 9.6 7.2 11.5 13 6.8 11.5 1.2 1 0 0 1 1 1 0 EBP50, C-terminal SR-25 PF10500.9 CDJ67943.1 - 0.0027 17.4 32.9 0.12 11.9 17.2 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ67943.1 - 0.017 15.1 0.5 0.018 14.9 0.5 1.1 1 0 0 1 1 1 0 SPX domain CCSAP PF15748.5 CDJ67943.1 - 0.15 12.3 8.0 1.9 8.6 1.6 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SUZ PF12752.7 CDJ67943.1 - 1.3 9.8 13.0 2.9 8.7 0.7 2.7 2 0 0 2 2 2 0 SUZ domain Secretin_N_2 PF07655.13 CDJ67943.1 - 3.2 8.4 17.1 2.4 8.7 7.6 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Urm1 PF09138.11 CDJ67945.1 - 7.7e-17 61.4 0.0 2.4e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) MAGE_N PF12440.8 CDJ67945.1 - 0.054 14.2 0.1 0.092 13.4 0.0 1.5 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal ThiS PF02597.20 CDJ67945.1 - 0.056 14.1 0.0 0.089 13.4 0.0 1.5 1 0 0 1 1 1 0 ThiS family LMBR1 PF04791.16 CDJ67946.1 - 1.3e-19 70.5 8.2 1.3e-19 70.5 8.2 2.0 2 1 0 2 2 2 1 LMBR1-like membrane protein SR-25 PF10500.9 CDJ67946.1 - 0.0059 16.2 6.2 0.0059 16.2 6.2 3.9 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein ETRAMP PF09716.10 CDJ67946.1 - 0.024 14.7 0.4 0.024 14.7 0.4 3.2 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF1980 PF09323.10 CDJ67946.1 - 0.044 13.7 0.1 0.044 13.7 0.1 4.3 3 2 1 4 4 4 0 Domain of unknown function (DUF1980) DUF2052 PF09747.9 CDJ67946.1 - 3.3 7.8 16.8 4.6 7.3 4.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF1180 PF06679.12 CDJ67946.1 - 3.5 8.0 16.8 2.6 8.4 0.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Trp_oprn_chp PF09534.10 CDJ67947.1 - 2.1 8.1 14.1 4.2 7.1 13.8 1.6 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3446 PF11928.8 CDJ67947.1 - 3.9 7.8 25.4 0.17 12.2 8.9 3.1 2 1 0 2 2 2 0 Early growth response N-terminal domain PARG_cat PF05028.14 CDJ67948.1 - 3.5e-14 52.9 0.0 8.3e-14 51.6 0.0 1.6 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) TACC_C PF05010.14 CDJ67948.1 - 0.036 13.8 0.3 0.036 13.8 0.3 1.6 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SR-25 PF10500.9 CDJ67948.1 - 0.63 9.6 6.0 1.1 8.8 6.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ67948.1 - 1 10.1 8.6 0.07 13.8 3.0 1.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein Asp5 PF17000.5 CDJ67948.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.7 3 1 0 3 3 3 0 Accessory secretory protein Sec, Asp5 RVT_1 PF00078.27 CDJ67949.1 - 2.7e-38 131.7 0.0 4.2e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PEPCK_ATP PF01293.20 CDJ67951.1 - 7.1e-39 133.8 3.8 2.4e-25 89.2 0.2 2.7 1 1 2 3 3 3 2 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 CDJ67951.1 - 0.015 15.4 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ67951.1 - 0.023 15.1 0.1 0.026 14.9 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CDJ67951.1 - 0.032 14.5 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ67951.1 - 0.072 13.6 0.0 0.079 13.5 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CDJ67951.1 - 0.079 12.7 0.4 0.14 11.9 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.6 CDJ67951.1 - 0.086 11.5 0.0 0.096 11.3 0.0 1.0 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDJ67951.1 - 0.092 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CDJ67951.1 - 0.095 13.2 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CDJ67951.1 - 0.11 12.4 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 CDJ67951.1 - 0.14 11.7 0.3 0.18 11.4 0.3 1.3 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 CDJ67951.1 - 0.24 11.0 0.0 0.3 10.7 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF243 PF03103.17 CDJ67954.1 - 8.6e-05 22.8 4.8 0.00014 22.1 4.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF243) Spt20 PF12090.8 CDJ67954.1 - 0.004 16.8 12.3 0.004 16.8 12.3 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ67954.1 - 0.0065 15.5 7.3 0.0063 15.5 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF945 PF06097.11 CDJ67954.1 - 0.027 13.6 3.4 0.029 13.5 3.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) MAGE PF01454.19 CDJ67954.1 - 0.071 12.8 2.6 0.091 12.4 2.6 1.1 1 0 0 1 1 1 0 MAGE family TFIIA PF03153.13 CDJ67954.1 - 0.077 13.0 13.3 0.073 13.1 13.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 CDJ67954.1 - 0.21 10.4 21.1 0.21 10.4 21.1 1.1 1 0 0 1 1 1 0 Androgen receptor DUF4834 PF16118.5 CDJ67954.1 - 0.44 11.5 2.4 0.53 11.3 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Med3 PF11593.8 CDJ67954.1 - 1.2 8.3 14.1 1.1 8.4 14.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAM70 PF14967.6 CDJ67954.1 - 8.9 5.7 6.3 9.3 5.6 6.3 1.2 1 0 0 1 1 1 0 FAM70 protein Ndc80_HEC PF03801.13 CDJ67956.1 - 2.9e-25 88.7 0.0 2.9e-25 88.7 0.0 3.0 3 1 0 3 3 3 1 HEC/Ndc80p family GAS PF13851.6 CDJ67956.1 - 0.00029 20.3 6.8 0.00029 20.3 6.8 3.9 2 2 1 3 3 3 2 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 CDJ67956.1 - 0.00046 20.3 23.2 0.00046 20.3 23.2 4.9 3 1 2 5 5 5 2 TPR/MLP1/MLP2-like protein ADIP PF11559.8 CDJ67956.1 - 9.1 6.3 90.0 0.05 13.7 23.0 5.1 2 2 3 5 5 5 0 Afadin- and alpha -actinin-Binding Shadoo PF14999.6 CDJ67958.1 - 0.0056 16.8 0.3 0.0063 16.6 0.3 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective RskA PF10099.9 CDJ67958.1 - 0.0091 16.3 2.4 0.01 16.1 2.4 1.0 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Adeno_PIX PF03955.14 CDJ67958.1 - 0.036 14.2 0.6 0.053 13.7 0.6 1.4 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) UL40 PF10682.9 CDJ67958.1 - 0.038 13.7 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 SUIM_assoc PF16619.5 CDJ67958.1 - 0.069 13.2 6.9 0.1 12.6 6.9 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CLN3 PF02487.17 CDJ67959.1 - 0.0021 17.2 11.4 0.0021 17.2 11.4 1.0 1 0 0 1 1 1 1 CLN3 protein Isy1 PF06246.12 CDJ67959.1 - 0.0035 16.9 16.8 0.0036 16.9 16.8 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DUF5102 PF17104.5 CDJ67959.1 - 0.0042 17.2 10.7 0.0047 17.0 10.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Pex14_N PF04695.13 CDJ67959.1 - 0.019 15.6 28.0 0.023 15.3 28.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3807 PF12720.7 CDJ67959.1 - 0.025 14.9 25.2 0.03 14.6 25.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) OATP PF03137.20 CDJ67959.1 - 0.053 11.8 8.9 0.067 11.5 8.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CPSF100_C PF13299.6 CDJ67959.1 - 0.054 13.7 13.0 0.059 13.6 13.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 CDJ67959.1 - 0.073 12.5 19.4 0.08 12.4 19.4 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ORC_WH_C PF18137.1 CDJ67959.1 - 0.088 12.9 14.0 0.098 12.7 14.0 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal TERB2 PF15101.6 CDJ67959.1 - 0.1 12.7 24.1 0.1 12.7 24.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DDHD PF02862.17 CDJ67959.1 - 0.12 12.5 15.6 0.12 12.5 15.6 1.1 1 0 0 1 1 1 0 DDHD domain DUF3408 PF11888.8 CDJ67959.1 - 0.16 12.1 18.1 0.19 11.9 18.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) EOS1 PF12326.8 CDJ67959.1 - 0.17 11.8 11.0 0.16 11.9 11.0 1.1 1 0 0 1 1 1 0 N-glycosylation protein DUF913 PF06025.12 CDJ67959.1 - 0.21 10.6 11.3 0.23 10.4 11.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 CDJ67959.1 - 0.22 9.8 17.7 0.22 9.8 17.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 CDJ67959.1 - 0.22 11.2 15.7 0.22 11.2 15.7 1.1 1 0 0 1 1 1 0 Connexin Band_3_cyto PF07565.13 CDJ67959.1 - 0.27 11.0 17.1 0.26 11.1 17.1 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain YABBY PF04690.13 CDJ67959.1 - 0.28 11.7 14.2 0.29 11.7 14.2 1.0 1 0 0 1 1 1 0 YABBY protein DUF2828 PF11443.8 CDJ67959.1 - 0.39 8.8 18.3 0.37 8.8 18.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) GNAT_acetyltr_2 PF13718.6 CDJ67959.1 - 0.45 9.9 11.0 0.45 9.9 11.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 GAGA_bind PF06217.12 CDJ67959.1 - 0.49 10.6 17.4 0.48 10.7 17.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family PIP5K PF01504.18 CDJ67959.1 - 0.53 9.5 15.9 0.51 9.5 15.9 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Peroxin-13_N PF04088.13 CDJ67959.1 - 0.56 10.5 9.3 0.7 10.2 9.3 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Velvet PF11754.8 CDJ67959.1 - 0.57 10.1 17.6 0.55 10.1 17.6 1.0 1 0 0 1 1 1 0 Velvet factor Baculo_PP31 PF05311.11 CDJ67959.1 - 0.58 9.6 16.3 0.59 9.6 16.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) eIF-3_zeta PF05091.12 CDJ67959.1 - 0.59 9.1 28.9 0.58 9.1 28.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ67959.1 - 0.67 8.7 24.3 0.7 8.6 24.3 1.0 1 0 0 1 1 1 0 Presenilin RPA43_OB PF17875.1 CDJ67959.1 - 0.7 10.5 11.6 1 10.0 11.6 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I SLC12 PF03522.15 CDJ67959.1 - 0.77 8.7 18.9 0.77 8.7 18.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Paf1 PF03985.13 CDJ67959.1 - 0.86 8.5 23.3 1 8.3 23.3 1.0 1 0 0 1 1 1 0 Paf1 PTPRCAP PF15713.5 CDJ67959.1 - 0.88 9.9 20.2 1 9.7 20.2 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Folate_carrier PF01770.18 CDJ67959.1 - 0.88 8.2 9.2 0.83 8.3 9.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier RR_TM4-6 PF06459.12 CDJ67959.1 - 0.91 9.3 20.2 0.97 9.2 20.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.6 CDJ67959.1 - 0.92 7.8 9.1 0.91 7.9 9.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ67959.1 - 0.95 9.5 13.5 0.9 9.6 13.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BORG_CEP PF14957.6 CDJ67959.1 - 1.2 10.3 11.6 1.4 10.1 11.6 1.1 1 0 0 1 1 1 0 Cdc42 effector Peptidase_S15 PF02129.18 CDJ67959.1 - 1.3 8.6 15.0 1.4 8.4 15.0 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Tim54 PF11711.8 CDJ67959.1 - 1.4 7.6 18.3 1.5 7.5 18.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4228 PF14009.6 CDJ67959.1 - 1.5 9.2 10.9 1.5 9.1 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) EFTUD2 PF16004.5 CDJ67959.1 - 1.5 9.4 20.4 1.9 9.1 20.4 1.1 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF1980 PF09323.10 CDJ67959.1 - 1.6 8.6 15.1 1.8 8.4 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CSG2 PF16965.5 CDJ67959.1 - 1.7 7.5 11.1 1.6 7.6 11.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator AIF_C PF14721.6 CDJ67959.1 - 1.7 9.0 15.7 2.2 8.7 15.7 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ureide_permease PF07168.11 CDJ67959.1 - 2 7.1 9.1 2.1 7.0 9.1 1.1 1 0 0 1 1 1 0 Ureide permease NPR3 PF03666.13 CDJ67959.1 - 2.1 7.0 18.8 2.2 7.0 18.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HemX PF04375.14 CDJ67959.1 - 2.3 7.4 40.9 2.5 7.3 40.9 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase EIIBC-GUT_N PF03612.14 CDJ67959.1 - 2.5 7.8 17.3 3.2 7.5 17.3 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DcuA_DcuB PF03605.14 CDJ67959.1 - 2.5 6.9 6.0 2.7 6.8 6.0 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter NARP1 PF12569.8 CDJ67959.1 - 2.8 6.8 18.8 2.9 6.7 18.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.10 CDJ67959.1 - 2.8 8.0 18.8 3.2 7.8 18.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Membralin PF09746.9 CDJ67959.1 - 2.8 6.9 12.1 2.7 6.9 12.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein Serinc PF03348.15 CDJ67959.1 - 2.9 6.7 13.1 3 6.7 13.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.22 CDJ67959.1 - 3.1 6.9 9.2 3.2 6.9 9.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter XRN_M PF17846.1 CDJ67959.1 - 3.1 6.6 14.4 3.2 6.6 14.4 1.0 1 0 0 1 1 1 0 Xrn1 helical domain CBP_BcsG PF11658.8 CDJ67959.1 - 3.2 6.0 14.7 3.1 6.1 14.7 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG AAA_23 PF13476.6 CDJ67959.1 - 3.3 8.2 23.3 3.8 8.0 23.3 1.2 1 0 0 1 1 1 0 AAA domain HCO3_cotransp PF00955.21 CDJ67959.1 - 3.3 6.4 7.6 3.5 6.3 7.6 1.0 1 0 0 1 1 1 0 HCO3- transporter family CobT PF06213.12 CDJ67959.1 - 3.5 6.9 31.9 4 6.8 31.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT R_equi_Vir PF05526.11 CDJ67959.1 - 3.7 7.4 7.6 4.1 7.2 7.6 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein TFIIA PF03153.13 CDJ67959.1 - 3.7 7.5 49.9 3.9 7.4 49.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2126 PF09899.9 CDJ67959.1 - 3.8 5.4 15.0 3.7 5.5 15.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Otopetrin PF03189.13 CDJ67959.1 - 4 6.1 11.2 3.9 6.2 11.2 1.0 1 0 0 1 1 1 0 Otopetrin MTP18 PF10558.9 CDJ67959.1 - 4.3 7.3 7.6 5.6 6.9 7.6 1.3 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) PAT1 PF09770.9 CDJ67959.1 - 4.4 5.5 34.0 4.4 5.4 34.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF853 PF05872.12 CDJ67959.1 - 4.4 5.8 16.6 4.5 5.8 16.6 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Ctr PF04145.15 CDJ67959.1 - 4.4 7.9 13.9 4.8 7.8 13.9 1.1 1 0 0 1 1 1 0 Ctr copper transporter family FAM176 PF14851.6 CDJ67959.1 - 5.3 6.7 14.7 6.1 6.5 14.7 1.1 1 0 0 1 1 1 0 FAM176 family Pal1 PF08316.11 CDJ67959.1 - 5.6 7.7 11.0 6.3 7.6 11.0 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Gti1_Pac2 PF09729.9 CDJ67959.1 - 6.2 6.9 19.0 6.9 6.7 19.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family FAM60A PF15396.6 CDJ67959.1 - 7.3 6.5 17.4 7.8 6.4 17.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Scs3p PF10261.9 CDJ67959.1 - 7.8 5.9 7.3 7.7 6.0 7.3 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2370 PF10176.9 CDJ67959.1 - 7.8 6.1 12.3 8.3 6.0 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) PPL5 PF18168.1 CDJ67959.1 - 9.1 5.5 16.5 9.9 5.4 16.5 1.0 1 0 0 1 1 1 0 Prim-pol family 5 SNF2_N PF00176.23 CDJ67960.1 - 1.7e-15 56.6 1.0 1.9e-15 56.4 1.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain RskA PF10099.9 CDJ67961.1 - 0.0014 19.0 13.5 0.0014 19.0 13.5 2.2 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ67961.1 - 0.051 12.3 24.8 0.071 11.9 24.8 1.2 1 0 0 1 1 1 0 Presenilin BAF1_ABF1 PF04684.13 CDJ67961.1 - 0.11 11.5 24.6 0.14 11.2 24.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Prothymosin PF03247.14 CDJ67961.1 - 0.33 11.4 14.2 0.31 11.5 5.9 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family SLC12 PF03522.15 CDJ67961.1 - 0.77 8.7 20.3 1.1 8.2 20.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SARAF PF06682.12 CDJ67961.1 - 0.93 9.1 20.7 4.1 6.9 20.7 1.8 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Peroxin-3 PF04882.12 CDJ67961.1 - 1.5 7.7 24.4 2 7.3 24.4 1.1 1 0 0 1 1 1 0 Peroxin-3 DUF4820 PF16091.5 CDJ67961.1 - 2.4 7.5 18.4 0.65 9.3 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) eIF-3_zeta PF05091.12 CDJ67961.1 - 3.2 6.6 28.3 3 6.7 5.9 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EOS1 PF12326.8 CDJ67961.1 - 8 6.4 13.3 9.9 6.1 5.0 2.1 2 0 0 2 2 2 0 N-glycosylation protein Spt20 PF12090.8 CDJ67961.1 - 9.1 5.8 63.6 0.25 10.9 17.7 2.1 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 CDJ67961.1 - 9.5 7.3 30.7 2.3 9.2 6.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PC_rep PF01851.22 CDJ67962.1 - 1.5e-09 37.8 21.2 0.0013 19.0 0.8 4.4 4 1 0 4 4 4 3 Proteasome/cyclosome repeat Dynein_IC2 PF11540.8 CDJ67962.1 - 0.28 11.1 0.1 0.42 10.6 0.1 1.2 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 Peptidase_M1_N PF17900.1 CDJ67963.1 - 2.9e-09 37.4 0.0 3.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Endonuclease_NS PF01223.23 CDJ67964.1 - 0.0018 18.1 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 2 DNA/RNA non-specific endonuclease Endonuclease_NS PF01223.23 CDJ67965.1 - 0.00082 19.2 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 2 DNA/RNA non-specific endonuclease SR-25 PF10500.9 CDJ67966.1 - 0.046 13.3 2.3 0.061 12.9 2.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 CDJ67967.1 - 1e-21 77.5 0.0 1.7e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBA_e1_thiolCys PF10585.9 CDJ67968.1 - 9e-17 61.8 0.6 2.2e-16 60.6 0.6 1.5 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site ThiF PF00899.21 CDJ67968.1 - 1.2e-06 28.1 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family SR-25 PF10500.9 CDJ67968.1 - 8.9e-05 22.2 16.7 8.9e-05 22.2 16.7 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ67968.1 - 0.015 14.2 6.9 0.014 14.3 6.2 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain TPX2_importin PF12214.8 CDJ67968.1 - 0.016 15.4 3.0 0.025 14.8 3.0 1.2 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein Macoilin PF09726.9 CDJ67968.1 - 0.018 13.6 4.7 0.019 13.6 4.7 1.1 1 0 0 1 1 1 0 Macoilin family Rrn6 PF10214.9 CDJ67968.1 - 0.029 12.9 6.1 0.037 12.5 6.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Herpes_pp85 PF04637.12 CDJ67968.1 - 0.039 12.4 9.2 0.053 11.9 9.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) LRRFIP PF09738.9 CDJ67968.1 - 0.067 12.7 11.5 0.09 12.2 11.5 1.1 1 0 0 1 1 1 0 LRRFIP family CDC45 PF02724.14 CDJ67968.1 - 0.11 10.8 3.0 0.12 10.7 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein POX PF07526.11 CDJ67968.1 - 0.3 11.7 5.1 0.56 10.8 5.1 1.4 1 0 0 1 1 1 0 Associated with HOX BUD22 PF09073.10 CDJ67968.1 - 0.42 9.9 14.2 0.54 9.5 14.2 1.1 1 0 0 1 1 1 0 BUD22 Bul1_C PF04426.12 CDJ67968.1 - 0.45 9.9 6.3 0.63 9.4 6.3 1.1 1 0 0 1 1 1 0 Bul1 C terminus DUF3446 PF11928.8 CDJ67968.1 - 0.88 9.9 22.1 0.18 12.1 16.8 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Lin-8 PF03353.15 CDJ67968.1 - 0.9 9.0 5.4 1.3 8.6 5.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AF-4 PF05110.13 CDJ67968.1 - 1.1 7.2 22.1 1.4 6.9 22.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Kinesin_assoc PF16183.5 CDJ67968.1 - 1.2 9.3 5.1 0.73 10.0 3.4 1.5 2 0 0 2 2 2 0 Kinesin-associated Cwf_Cwc_15 PF04889.12 CDJ67968.1 - 1.9 8.2 9.5 2.8 7.6 9.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peroxin-3 PF04882.12 CDJ67968.1 - 4 6.3 9.8 5.3 5.9 9.8 1.1 1 0 0 1 1 1 0 Peroxin-3 PI3K_1B_p101 PF10486.9 CDJ67968.1 - 6.2 4.5 11.3 8.2 4.1 11.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DHHW PF14286.6 CDJ67968.1 - 6.7 5.9 6.2 9.4 5.4 6.2 1.1 1 0 0 1 1 1 0 DHHW protein zf-CCHC PF00098.23 CDJ67969.1 - 0.0011 19.0 0.8 0.0011 19.0 0.8 1.8 2 0 0 2 2 2 1 Zinc knuckle Cofac_haem_bdg PF04187.13 CDJ67969.1 - 0.026 14.5 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Sec63 PF02889.16 CDJ67970.1 - 5.2e-40 137.2 0.0 8.7e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 CDJ67970.1 - 9.6e-30 103.6 0.0 2.1e-17 63.4 0.0 2.9 3 0 0 3 3 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CDJ67970.1 - 1.5e-12 47.8 0.3 0.00021 21.4 0.0 4.0 3 1 0 3 3 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ67970.1 - 3.9e-09 36.8 0.0 0.007 16.7 0.0 4.4 2 2 0 2 2 2 2 Helicase conserved C-terminal domain T2SSE PF00437.20 CDJ67970.1 - 2.8e-05 23.3 0.0 0.35 9.9 0.0 3.3 3 0 0 3 3 3 2 Type II/IV secretion system protein DUF2722 PF10846.8 CDJ67970.1 - 0.0011 18.0 10.0 0.0011 18.0 10.0 5.6 5 1 0 5 5 5 3 Protein of unknown function (DUF2722) AAA_7 PF12775.7 CDJ67970.1 - 0.0048 16.4 0.1 3.5 7.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region SPX PF03105.19 CDJ67970.1 - 0.0093 15.9 48.6 0.82 9.5 13.4 4.6 4 1 0 4 4 4 2 SPX domain DUF4667 PF15700.5 CDJ67970.1 - 0.0096 16.0 0.9 0.0096 16.0 0.9 6.9 6 2 0 6 6 4 2 Domain of unknown function (DUF4667) AAA_19 PF13245.6 CDJ67970.1 - 0.013 15.8 0.0 5.9 7.2 0.0 3.6 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CDJ67970.1 - 2.6 7.8 23.3 1.5 8.6 0.0 5.0 6 0 0 6 6 5 0 AAA domain Apt1 PF10351.9 CDJ67970.1 - 3.8 6.3 37.9 0.044 12.6 0.9 4.6 4 0 0 4 4 4 0 Golgi-body localisation protein domain UPF0086 PF01868.16 CDJ67971.1 - 7.8e-07 28.9 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Spt20 PF12090.8 CDJ67971.1 - 0.00024 20.8 59.1 0.011 15.4 8.3 3.2 3 0 0 3 3 3 3 Spt20 family DUF2235 PF09994.9 CDJ67971.1 - 0.015 14.6 0.8 0.015 14.6 0.8 2.1 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) RR_TM4-6 PF06459.12 CDJ67971.1 - 0.33 10.8 15.8 0.51 10.1 15.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4517 PF15006.6 CDJ67971.1 - 2.4 8.3 7.4 5.5 7.1 7.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4517) Spc42p PF11544.8 CDJ67972.1 - 0.00033 20.6 2.6 0.00033 20.6 2.6 9.0 8 2 2 10 10 10 2 Spindle pole body component Spc42p RAP1 PF07218.11 CDJ67973.1 - 0.42 8.8 15.6 0.92 7.7 15.6 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TraT PF05818.12 CDJ67974.1 - 0.1 12.3 4.3 0.12 12.1 4.3 1.0 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Histone PF00125.24 CDJ67975.1 - 3e-35 121.4 3.3 3.1e-34 118.2 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CDJ67975.1 - 7.2e-05 22.9 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CDJ67975.1 - 0.061 13.7 0.0 0.088 13.2 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein Spt20 PF12090.8 CDJ67975.1 - 1.2 8.6 13.4 1.7 8.2 13.4 1.2 1 0 0 1 1 1 0 Spt20 family DUF3138 PF11336.8 CDJ67976.1 - 2.9 6.4 14.0 2.6 6.6 14.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2057 PF09829.9 CDJ67976.1 - 6.6 6.8 8.4 6.4 6.9 8.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF4342 PF14242.6 CDJ67976.1 - 8.5 6.5 10.0 10 6.2 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) SPX PF03105.19 CDJ67977.1 - 0.0011 18.9 1.1 0.0011 18.9 1.1 1.1 1 0 0 1 1 1 1 SPX domain BBS2_N PF14781.6 CDJ67977.1 - 0.013 15.4 0.6 0.035 14.0 0.6 1.7 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Apt1 PF10351.9 CDJ67977.1 - 0.044 12.6 0.7 0.041 12.7 0.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ipi1_N PF12333.8 CDJ67977.1 - 0.096 13.3 3.6 0.24 12.0 2.9 2.0 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation AF-4 PF05110.13 CDJ67977.1 - 1.1 7.3 18.1 1.2 7.1 18.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MerC PF03203.14 CDJ67978.1 - 1.8e-17 63.9 7.5 1.4e-16 61.0 7.2 2.2 2 0 0 2 2 2 1 MerC mercury resistance protein SPX PF03105.19 CDJ67978.1 - 0.00047 20.2 18.1 0.00088 19.3 7.7 2.1 2 0 0 2 2 2 2 SPX domain SUIM_assoc PF16619.5 CDJ67978.1 - 0.003 17.6 0.5 0.003 17.6 0.5 3.8 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ67978.1 - 1 9.3 28.0 1.6 8.6 8.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hydrolase_like PF13242.6 CDJ67979.1 - 1.9e-08 34.2 0.0 1.1e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hid1 PF12722.7 CDJ67979.1 - 0.0009 17.5 3.6 0.0009 17.5 3.6 2.1 2 0 0 2 2 2 2 High-temperature-induced dauer-formation protein SPX PF03105.19 CDJ67979.1 - 0.0047 16.9 17.9 0.0069 16.4 17.9 1.2 1 0 0 1 1 1 1 SPX domain CAF1 PF04857.20 CDJ67979.1 - 0.0051 16.0 13.5 0.033 13.4 0.1 2.2 2 0 0 2 2 2 1 CAF1 family ribonuclease PGP_phosphatase PF09419.10 CDJ67979.1 - 0.02 14.5 0.0 0.063 12.9 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Endostatin PF06482.11 CDJ67979.1 - 0.22 10.9 27.4 0.36 10.3 11.5 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin DUF4484 PF14831.6 CDJ67979.1 - 0.46 10.5 19.3 0.1 12.6 2.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4484) Presenilin PF01080.17 CDJ67979.1 - 0.51 9.0 35.1 0.21 10.3 10.9 2.3 2 0 0 2 2 2 0 Presenilin Sin_N PF04801.13 CDJ67979.1 - 0.6 9.3 44.0 0.0072 15.6 11.8 2.4 2 1 0 2 2 2 0 Sin-like protein conserved region Gti1_Pac2 PF09729.9 CDJ67979.1 - 0.98 9.5 23.5 2.4 8.2 8.0 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family SRP-alpha_N PF04086.13 CDJ67979.1 - 1.7 8.5 26.3 3.2 7.6 9.1 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF2828 PF11443.8 CDJ67979.1 - 9.6 4.2 25.1 2.6 6.0 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Retrotrans_gag PF03732.17 CDJ67980.1 - 1.8e-06 28.1 0.5 0.19 12.1 0.0 3.5 4 0 0 4 4 4 2 Retrotransposon gag protein SSI PF00720.17 CDJ67980.1 - 0.0061 16.5 0.2 5.6 7.0 0.0 2.5 2 0 0 2 2 2 2 Subtilisin inhibitor-like NOB1_Zn_bind PF08772.11 CDJ67980.1 - 0.015 15.5 0.0 9.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Phe_ZIP PF08916.11 CDJ67980.1 - 0.52 11.1 6.3 2.2e+02 2.6 0.1 5.2 6 0 0 6 6 6 0 Phenylalanine zipper ELO PF01151.18 CDJ67981.1 - 8.5e-09 35.3 1.1 1.4e-08 34.6 0.5 1.6 1 1 1 2 2 2 1 GNS1/SUR4 family TCP PF03634.13 CDJ67981.1 - 0.048 14.2 11.5 0.046 14.3 2.4 3.1 3 0 0 3 3 3 0 TCP family transcription factor TFIIA PF03153.13 CDJ67981.1 - 7.6 6.4 17.2 1.1 9.1 13.4 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribo_biogen_C PF04034.13 CDJ67982.1 - 0.23 11.2 1.7 0.33 10.7 0.1 2.1 2 0 0 2 2 2 0 Ribosome biogenesis protein, C-terminal XRN_M PF17846.1 CDJ67984.1 - 0.0037 16.3 15.1 0.0037 16.3 15.1 3.1 2 1 1 3 3 3 1 Xrn1 helical domain Utp14 PF04615.13 CDJ67984.1 - 1.1 7.8 62.1 1.2 7.7 35.6 2.1 2 0 0 2 2 2 0 Utp14 protein Rpp20 PF12328.8 CDJ67984.1 - 1.5 8.8 0.0 1.5 8.8 0.0 6.9 5 2 0 5 5 5 0 Rpp20 subunit of nuclear RNase MRP and P Ribosomal_60s PF00428.19 CDJ67985.1 - 0.00074 20.1 9.9 0.00074 20.1 9.9 9.5 7 2 2 9 9 9 4 60s Acidic ribosomal protein HAT PF02184.16 CDJ67986.1 - 4.8e-07 29.6 2.1 0.012 15.5 0.0 3.4 3 0 0 3 3 3 2 HAT (Half-A-TPR) repeat Spt20 PF12090.8 CDJ67986.1 - 0.01 15.5 15.0 0.016 14.8 15.0 1.3 1 0 0 1 1 1 0 Spt20 family TPR_14 PF13428.6 CDJ67986.1 - 0.014 16.2 2.2 6.1 7.9 0.0 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 CDJ67986.1 - 0.017 15.1 17.1 0.97 9.5 17.0 2.8 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2844 PF11005.8 CDJ67986.1 - 0.03 14.3 2.7 0.062 13.3 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) U3_assoc_6 PF08640.11 CDJ67986.1 - 0.049 13.7 4.5 0.43 10.7 0.2 3.0 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DUF2722 PF10846.8 CDJ67986.1 - 0.062 12.2 13.0 0.091 11.7 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ67986.1 - 0.066 12.2 19.1 0.1 11.6 19.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4834 PF16118.5 CDJ67986.1 - 0.3 12.1 4.4 0.11 13.5 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 CDJ67986.1 - 2.5 6.9 16.0 3.2 6.5 16.0 1.2 1 0 0 1 1 1 0 Androgen receptor RLL PF10036.9 CDJ67987.1 - 0.0045 16.9 8.3 0.0052 16.7 8.3 1.1 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein DUF1439 PF07273.12 CDJ67987.1 - 0.015 15.2 0.3 0.019 14.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1439) LRR_8 PF13855.6 CDJ67989.1 - 4e-07 29.7 32.2 3.2e-05 23.6 5.7 4.9 3 1 0 4 4 4 4 Leucine rich repeat MyTH4 PF00784.17 CDJ67990.1 - 0.021 15.3 0.4 0.032 14.7 0.4 1.3 1 0 0 1 1 1 0 MyTH4 domain MORN PF02493.20 CDJ67991.1 - 4.1e-12 45.3 15.6 7e-06 25.6 0.7 4.8 5 0 0 5 5 5 3 MORN repeat SAM_1 PF00536.30 CDJ67991.1 - 1.4e-06 28.6 0.3 9.6e-06 25.9 0.2 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDJ67991.1 - 0.0021 18.1 0.3 0.004 17.2 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TFIIA PF03153.13 CDJ67991.1 - 0.21 11.5 22.2 0.13 12.2 6.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PriC PF07445.12 CDJ67991.1 - 0.85 9.5 26.2 0.058 13.3 7.3 2.4 2 1 0 2 2 2 0 Primosomal replication protein priC SR-25 PF10500.9 CDJ67991.1 - 1.9 8.1 16.5 0.17 11.5 8.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ67991.1 - 3.8 6.2 4.0 14 4.4 0.4 2.0 2 0 0 2 2 2 0 Presenilin AMPK1_CBM PF16561.5 CDJ67992.1 - 7.6e-18 64.5 0.0 1.9e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glycos_transf_1 PF00534.20 CDJ67992.1 - 6.6e-06 25.8 0.0 2.2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ67992.1 - 0.0097 16.3 0.0 0.024 15.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Macoilin PF09726.9 CDJ67992.1 - 0.21 10.1 8.2 0.29 9.6 8.2 1.1 1 0 0 1 1 1 0 Macoilin family Sec3_C PF09763.9 CDJ67992.1 - 0.81 8.0 4.3 0.99 7.7 4.3 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 LRRFIP PF09738.9 CDJ67992.1 - 0.88 9.0 8.0 1.4 8.3 8.0 1.2 1 0 0 1 1 1 0 LRRFIP family Herpes_capsid PF06112.11 CDJ67992.1 - 4.2 7.4 14.3 9.3 6.3 14.3 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Apt1 PF10351.9 CDJ67992.1 - 6 5.6 10.9 8.1 5.2 10.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ESM4 PF15952.5 CDJ67993.1 - 0.0033 17.9 14.7 0.0033 17.9 14.7 7.7 7 2 0 7 7 7 1 Enhancer of split M4 family Gp58 PF07902.11 CDJ67994.1 - 0.26 9.5 8.7 0.32 9.2 8.7 1.2 1 0 0 1 1 1 0 gp58-like protein Bax1-I PF01027.20 CDJ67995.1 - 2.3e-30 106.0 35.1 2.6e-30 105.8 35.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF368 PF04018.13 CDJ67995.1 - 2.6 7.6 23.5 0.014 14.9 11.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF368) RskA PF10099.9 CDJ67996.1 - 2.4e-05 24.7 0.4 2.4e-05 24.7 0.4 6.2 3 2 1 4 4 4 3 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ67996.1 - 0.0067 15.4 9.1 0.0067 15.4 9.1 7.2 7 0 0 7 7 7 4 Protein of unknown function (DUF2722) DUF2973 PF11189.8 CDJ67996.1 - 0.05 13.7 0.3 0.05 13.7 0.3 5.9 6 0 0 6 6 6 0 Protein of unknown function (DUF2973) Orf78 PF06024.12 CDJ67996.1 - 0.21 11.9 16.3 4.2 7.7 0.3 5.8 5 1 0 5 5 5 0 Orf78 (ac78) Glt_symporter PF03616.14 CDJ67996.1 - 0.88 8.2 5.5 2 7.0 0.2 2.9 3 0 0 3 3 3 0 Sodium/glutamate symporter MTABC_N PF16185.5 CDJ67996.1 - 1.4 8.3 8.8 2.1 7.8 0.2 3.2 3 0 0 3 3 3 0 Mitochondrial ABC-transporter N-terminal five TM region rve PF00665.26 CDJ67998.1 - 6.6e-08 32.8 0.0 1.6e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RRM_1 PF00076.22 CDJ67999.1 - 1.2e-18 66.7 0.1 2.1e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoU_methylase PF00588.19 CDJ68001.1 - 3.4e-09 37.0 0.0 7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SUIM_assoc PF16619.5 CDJ68002.1 - 0.012 15.6 6.6 0.012 15.6 6.6 8.1 5 3 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 CH_2 PF06294.11 CDJ68003.1 - 1.3e-16 60.4 0.0 6.7e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 CH-like domain in sperm protein FAM60A PF15396.6 CDJ68003.1 - 0.0001 22.4 12.7 0.0001 22.4 12.7 7.1 7 1 0 7 7 7 2 Protein Family FAM60A Spt20 PF12090.8 CDJ68003.1 - 0.00051 19.7 3.8 0.00051 19.7 3.8 8.6 7 1 0 7 7 7 3 Spt20 family SR-25 PF10500.9 CDJ68003.1 - 0.0016 18.1 16.3 0.0016 18.1 16.3 9.6 10 1 1 11 11 11 1 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ68003.1 - 0.0054 17.3 13.0 0.0054 17.3 13.0 9.5 9 1 2 11 11 11 1 TCP family transcription factor Apt1 PF10351.9 CDJ68003.1 - 2.4 6.9 0.0 2.4 6.9 0.0 6.9 6 1 2 8 8 8 0 Golgi-body localisation protein domain Cellulose_synt PF03552.14 CDJ68003.1 - 5.9 5.3 5.2 13 4.2 5.2 1.4 1 0 0 1 1 1 0 Cellulose synthase DUF2722 PF10846.8 CDJ68004.1 - 0.0026 16.8 9.1 0.0026 16.8 9.1 6.3 6 1 0 6 6 6 3 Protein of unknown function (DUF2722) 7tm_2 PF00002.24 CDJ68004.1 - 1.9 7.7 7.7 0.034 13.4 0.4 1.8 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) DnaJ PF00226.31 CDJ68005.1 - 4.9e-16 58.6 0.0 6.9e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain TAP42 PF04177.12 CDJ68006.1 - 3.4e-26 92.2 7.9 2.5e-16 59.7 0.0 2.9 2 1 1 3 3 3 2 TAP42-like family RskA PF10099.9 CDJ68006.1 - 0.0068 16.7 19.4 0.02 15.2 8.9 2.5 2 0 0 2 2 2 2 Anti-sigma-K factor rskA SPX PF03105.19 CDJ68006.1 - 0.12 12.2 12.2 0.22 11.4 12.2 1.4 1 0 0 1 1 1 0 SPX domain SMI1_KNR4 PF09346.10 CDJ68006.1 - 0.15 12.4 0.3 4.6 7.6 0.1 2.5 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) TFIIA PF03153.13 CDJ68006.1 - 0.45 10.5 18.6 0.05 13.6 12.8 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ68006.1 - 6.5 6.2 12.7 1.7 8.1 4.6 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Thx PF17070.5 CDJ68008.1 - 0.27 11.4 0.4 1.4 9.1 0.2 1.9 2 0 0 2 2 2 0 30S ribosomal protein Thx Tic110 PF16940.5 CDJ68008.1 - 2.1 6.7 11.3 1.8 7.0 11.3 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Hc1 PF07432.13 CDJ68008.1 - 3.9 7.9 20.8 4.3 7.7 20.8 1.1 1 0 0 1 1 1 0 Histone H1-like protein Hc1 R_equi_Vir PF05526.11 CDJ68008.1 - 5 6.9 10.0 5.4 6.8 10.0 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF2722 PF10846.8 CDJ68009.1 - 4.5e-06 25.9 6.1 0.0013 17.7 3.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ68009.1 - 8.3e-05 22.3 4.4 8.3e-05 22.3 4.4 2.1 2 0 0 2 2 2 2 Spt20 family Neuregulin PF02158.15 CDJ68009.1 - 0.43 9.9 13.3 0.82 9.0 4.6 2.2 2 0 0 2 2 2 0 Neuregulin intracellular region YABBY PF04690.13 CDJ68009.1 - 0.46 11.0 5.7 0.23 12.0 2.3 2.0 2 0 0 2 2 2 0 YABBY protein Suf PF05843.14 CDJ68009.1 - 0.67 9.9 8.6 1.7 8.6 3.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SARAF PF06682.12 CDJ68009.1 - 2.5 7.7 12.6 1.1 8.8 4.3 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Pex14_N PF04695.13 CDJ68009.1 - 2.9 8.5 18.3 1.5 9.5 5.7 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 CDJ68009.1 - 3.5 8.7 10.2 1.4 9.9 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CKAP2_C PF15297.6 CDJ68009.1 - 6.4 5.8 7.0 0.17 10.9 0.6 1.5 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus ABC_membrane PF00664.23 CDJ68011.1 - 7.9e-27 94.6 0.0 1e-26 94.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AP2 PF00847.20 CDJ68012.1 - 7.6e-10 38.9 0.9 7.6e-10 38.9 0.9 3.8 4 0 0 4 4 4 1 AP2 domain RskA PF10099.9 CDJ68012.1 - 0.0052 17.1 8.5 0.0052 17.1 8.5 9.6 1 1 6 7 7 7 2 Anti-sigma-K factor rskA Surface_antigen PF11054.8 CDJ68013.1 - 8.5e-15 55.1 0.0 9.8e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen zinc_ribbon_10 PF10058.9 CDJ68013.1 - 0.021 14.6 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF2950 PF11453.8 CDJ68013.1 - 0.17 11.1 0.1 0.17 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Retrotrans_gag PF03732.17 CDJ68014.1 - 8.1e-06 26.0 0.0 3e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 CDJ68014.1 - 3.7e-05 23.6 2.6 3.7e-05 23.6 2.6 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ68014.1 - 0.013 15.3 0.8 0.031 14.1 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ68014.1 - 0.023 14.7 0.7 0.056 13.4 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ68014.1 - 0.89 9.3 5.9 0.71 9.6 2.1 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Integrase_H2C2 PF17921.1 CDJ68015.1 - 9.4e-17 60.9 1.6 2.8e-16 59.4 1.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ68015.1 - 1.6e-16 60.6 0.0 3.5e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDJ68015.1 - 0.00017 21.8 0.4 0.00037 20.6 0.4 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDJ68015.1 - 0.027 14.2 0.2 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 Integrase core domain Cation_ATPase_C PF00689.21 CDJ68017.1 - 1.3e-52 178.1 2.5 2.6e-52 177.2 2.5 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CDJ68017.1 - 3.7e-50 169.9 2.0 3e-49 167.0 0.2 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ68017.1 - 1.4e-20 74.5 3.7 3.4e-19 70.0 3.7 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ68017.1 - 4.5e-20 71.5 0.0 8.9e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CDJ68017.1 - 9.5e-19 66.9 0.1 4.9e-18 64.6 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDJ68017.1 - 1.3e-05 25.1 0.5 7.6e-05 22.6 0.5 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ68017.1 - 0.0034 17.8 0.0 0.01 16.2 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ68017.1 - 0.18 12.0 0.0 0.6 10.2 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CLN3 PF02487.17 CDJ68018.1 - 0.024 13.7 1.1 0.056 12.5 1.1 1.6 1 0 0 1 1 1 0 CLN3 protein DUF1600 PF07667.11 CDJ68018.1 - 0.35 11.1 2.2 0.74 10.0 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) Methyltrans_RNA PF04452.14 CDJ68019.1 - 5e-33 114.3 0.0 3.8e-18 65.6 0.0 2.2 2 0 0 2 2 2 2 RNA methyltransferase AbiEi_3 PF11459.8 CDJ68019.1 - 0.0033 17.1 0.1 0.0064 16.2 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Presenilin PF01080.17 CDJ68019.1 - 0.33 9.7 1.9 0.68 8.6 0.6 1.9 2 0 0 2 2 2 0 Presenilin SUIM_assoc PF16619.5 CDJ68019.1 - 0.91 9.6 20.6 0.46 10.6 3.3 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RsfS PF02410.15 CDJ68020.1 - 6.2e-13 49.0 0.0 1.5e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation zf-C3HC4 PF00097.25 CDJ68021.1 - 0.0028 17.5 10.8 0.0028 17.5 10.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ68021.1 - 0.0077 16.2 11.1 0.0077 16.2 11.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ68021.1 - 3 7.8 19.4 0.28 11.1 11.8 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ68021.1 - 3.6 8.0 22.6 0.05 14.0 11.5 2.3 1 1 1 2 2 2 0 Ring finger domain RAP PF08373.10 CDJ68022.1 - 4.2e-17 62.0 0.0 6.7e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 CDJ68022.1 - 2.1e-05 24.6 0.1 3.9e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 REase_MTES_1575 Retrotrans_gag PF03732.17 CDJ68023.1 - 8.8e-12 45.1 0.4 1e-05 25.7 0.0 2.6 3 0 0 3 3 3 2 Retrotransposon gag protein AIM5 PF17050.5 CDJ68023.1 - 0.0038 18.0 0.2 1.6 9.6 0.0 2.6 2 0 0 2 2 2 1 Altered inheritance of mitochondria 5 UPF0137 PF03677.13 CDJ68023.1 - 0.023 14.5 0.0 3 7.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0137) PI-TkoII_IV PF18714.1 CDJ68023.1 - 0.033 13.6 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase II intein Domain IV DUF987 PF06174.11 CDJ68023.1 - 0.056 13.4 0.0 7.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF987) KicB PF03882.14 CDJ68023.1 - 0.071 13.3 0.0 4.9 7.4 0.0 2.4 2 0 0 2 2 2 0 MukF winged-helix domain VAPB_antitox PF02697.14 CDJ68023.1 - 0.074 13.8 0.0 21 6.0 0.0 2.2 2 0 0 2 2 2 0 Putative antitoxin TRCF PF03461.15 CDJ68023.1 - 0.12 12.7 0.0 17 5.9 0.0 2.3 2 0 0 2 2 2 0 TRCF domain Gemini_AC4_5 PF04807.12 CDJ68023.1 - 0.4 10.4 1.8 8 6.2 0.0 3.5 4 0 0 4 4 4 0 Geminivirus AC4/5 conserved region SpoIIP PF07454.11 CDJ68024.1 - 0.0086 15.6 10.3 0.0086 15.6 10.3 2.2 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) CNDH2_C PF16858.5 CDJ68024.1 - 0.011 15.7 7.5 0.011 15.7 7.5 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF1980 PF09323.10 CDJ68024.1 - 0.25 11.2 14.8 0.18 11.7 6.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) EOS1 PF12326.8 CDJ68024.1 - 0.74 9.7 9.4 0.14 12.1 2.3 2.2 2 0 0 2 2 2 0 N-glycosylation protein CIAPIN1 PF05093.13 CDJ68024.1 - 0.88 10.1 18.8 0.72 10.4 3.8 2.8 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis MecA PF05389.12 CDJ68024.1 - 1.3 8.6 15.5 0.033 13.8 4.5 2.2 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) FAM60A PF15396.6 CDJ68024.1 - 1.4 8.9 18.5 0.3 11.1 7.9 2.4 2 0 0 2 2 2 0 Protein Family FAM60A PAT1 PF09770.9 CDJ68024.1 - 2.5 6.2 60.7 0.037 12.3 31.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 EIIBC-GUT_N PF03612.14 CDJ68024.1 - 3.1 7.5 24.4 0.064 13.0 10.5 2.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus MMR1 PF08505.10 CDJ68024.1 - 3.6 7.8 35.2 0.43 10.8 18.0 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein eIF-3_zeta PF05091.12 CDJ68024.1 - 5.3 5.9 36.2 0.34 9.8 19.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.6 CDJ68024.1 - 6.3 5.1 8.6 0.44 8.9 2.2 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Rxt3 PF08642.10 CDJ68024.1 - 7.4 7.4 13.7 1.2 10.0 4.6 2.6 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Connexin PF00029.19 CDJ68024.1 - 9.7 5.9 20.0 0.78 9.5 9.4 2.1 2 0 0 2 2 2 0 Connexin FAM176 PF14851.6 CDJ68025.1 - 0.016 14.9 1.0 0.016 14.9 1.0 3.6 5 0 0 5 5 5 0 FAM176 family TFIIA PF03153.13 CDJ68025.1 - 0.31 11.0 66.1 1.1 9.1 22.8 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ68025.1 - 0.93 9.6 62.4 0.87 9.7 4.7 6.4 5 1 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 BAF1_ABF1 PF04684.13 CDJ68025.1 - 5.3 6.0 30.5 0.59 9.1 9.6 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor CYSTM PF12734.7 CDJ68026.1 - 0.00026 21.2 11.5 0.00026 21.2 11.5 7.4 6 1 0 6 6 2 1 Cysteine-rich TM module stress tolerance Caldesmon PF02029.15 CDJ68026.1 - 0.0015 17.4 16.0 0.27 10.0 0.0 3.4 2 1 1 3 3 2 1 Caldesmon DUF2722 PF10846.8 CDJ68026.1 - 0.0031 16.5 12.0 0.0031 16.5 12.0 5.3 4 2 0 5 5 2 1 Protein of unknown function (DUF2722) DUF1980 PF09323.10 CDJ68026.1 - 0.02 14.8 0.4 0.02 14.8 0.4 4.1 3 1 1 4 4 3 0 Domain of unknown function (DUF1980) MecA PF05389.12 CDJ68026.1 - 0.027 14.1 20.3 0.3 10.7 3.2 3.7 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) Frizzled PF01534.17 CDJ68026.1 - 0.04 12.9 0.0 6.9 5.6 0.0 2.4 2 0 0 2 2 2 0 Frizzled/Smoothened family membrane region Otopetrin PF03189.13 CDJ68026.1 - 0.34 9.7 10.8 4.6 5.9 0.2 3.4 3 0 0 3 3 3 0 Otopetrin PIG-U PF06728.13 CDJ68026.1 - 0.65 9.0 11.3 0.24 10.4 0.6 3.1 3 0 0 3 3 3 0 GPI transamidase subunit PIG-U DUF1269 PF06897.12 CDJ68026.1 - 1.1 9.5 0.0 1.1 9.5 0.0 5.6 4 1 0 4 4 3 0 Protein of unknown function (DUF1269) TMEM223 PF14640.6 CDJ68026.1 - 1.5 9.0 7.5 5.2 7.2 0.1 4.3 5 0 0 5 5 5 0 Transmembrane protein 223 OATP PF03137.20 CDJ68026.1 - 4.1 5.6 10.4 0.53 8.5 0.8 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2371 PF10177.9 CDJ68026.1 - 7.1 6.8 8.2 73 3.5 0.0 3.9 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) Bax1-I PF01027.20 CDJ68027.1 - 0.00016 21.6 0.3 0.00017 21.5 0.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Ribosomal_L4 PF00573.22 CDJ68030.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Apt1 PF10351.9 CDJ68030.1 - 1.3 7.8 12.1 1.5 7.6 12.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ68030.1 - 3.1 7.6 14.2 3.6 7.4 14.2 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CDJ68030.1 - 5.3 5.5 16.3 7.5 5.0 16.3 1.2 1 0 0 1 1 1 0 Macoilin family Ribosomal_S15 PF00312.22 CDJ68031.1 - 3.7e-10 39.9 2.2 3.7e-10 39.9 2.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_L6e PF01159.19 CDJ68031.1 - 0.059 13.9 2.8 0.1 13.2 2.8 1.3 1 0 0 1 1 1 0 Ribosomal protein L6e Ribosomal_S15 PF00312.22 CDJ68032.1 - 0.00067 19.8 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 SUIM_assoc PF16619.5 CDJ68032.1 - 0.0064 16.5 3.6 0.0064 16.5 3.6 2.7 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ68032.1 - 0.0087 15.7 19.1 0.11 12.0 10.4 2.1 2 0 0 2 2 2 2 Spt20 family PBP1_TM PF14812.6 CDJ68032.1 - 1 9.8 5.6 14 6.2 1.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4834 PF16118.5 CDJ68032.1 - 2 9.4 10.1 4.4 8.3 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF5345 PF17280.2 CDJ68032.1 - 3.1 7.8 16.1 0.95 9.5 0.6 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) YbgS PF13985.6 CDJ68032.1 - 4 7.7 9.5 2.9 8.2 7.7 1.6 1 1 1 2 2 2 0 YbgS-like protein MMR_HSR1 PF01926.23 CDJ68033.1 - 6.6e-13 48.7 0.0 3.3e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 CDJ68033.1 - 2.5e-09 36.9 13.8 4.6e-05 23.0 5.8 3.7 2 2 0 2 2 2 2 GTP1/OBG FeoB_N PF02421.18 CDJ68033.1 - 0.00017 21.2 0.0 0.011 15.2 0.0 2.8 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDJ68033.1 - 0.0045 16.5 2.7 0.0064 16.1 1.6 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 CDJ68033.1 - 0.17 11.5 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.13 CDJ68033.1 - 0.63 10.0 47.5 1.6 8.7 36.7 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ATP_bind_1 PF03029.17 CDJ68033.1 - 0.98 9.1 4.7 11 5.6 3.6 2.6 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein CLN3 PF02487.17 CDJ68033.1 - 1.4 7.9 3.2 2.5 7.0 3.2 1.4 1 0 0 1 1 1 0 CLN3 protein AAA_28 PF13521.6 CDJ68033.1 - 1.9 8.7 4.6 2 8.7 0.0 2.9 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 CDJ68033.1 - 7.5 7.1 13.8 5.2e+02 1.1 13.8 2.7 1 1 0 1 1 1 0 ABC transporter Ribosomal_L24e PF01246.20 CDJ68034.1 - 4.3e-32 110.2 5.5 9.5e-32 109.0 5.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.14 CDJ68034.1 - 0.019 14.9 2.9 0.019 14.9 2.9 2.0 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif TFIIA PF03153.13 CDJ68034.1 - 0.022 14.8 16.4 0.025 14.6 16.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit STAC2_u1 PF16664.5 CDJ68034.1 - 0.084 13.3 8.8 0.13 12.7 8.8 1.4 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 AAA_22 PF13401.6 CDJ68034.1 - 0.74 10.1 5.8 1.6 9.0 5.8 1.5 1 0 0 1 1 1 0 AAA domain BIRC6 PF12356.8 CDJ68034.1 - 0.82 9.1 9.5 1.3 8.4 9.5 1.2 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 DUF4820 PF16091.5 CDJ68034.1 - 2.4 7.5 14.4 2.5 7.4 13.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) GOLD_2 PF13897.6 CDJ68034.1 - 4.1 7.9 6.8 1.3e+02 3.0 5.4 2.8 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking Sld5 PF05916.11 CDJ68035.1 - 2.1e-05 24.9 0.0 3.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF4205 PF13898.6 CDJ68036.1 - 8.9e-49 166.3 0.0 2.3e-48 164.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) WD40 PF00400.32 CDJ68037.1 - 4.1e-05 24.3 11.1 0.0083 17.0 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat AMA-1 PF02430.15 CDJ68038.1 - 2.4e-66 224.6 0.1 5.3e-66 223.5 0.1 1.5 1 1 0 1 1 1 1 Apical membrane antigen 1 FAP206 PF12018.8 CDJ68039.1 - 0.0099 15.4 0.0 0.035 13.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function AAA_33 PF13671.6 CDJ68039.1 - 0.022 14.9 0.2 0.079 13.1 0.2 1.9 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 CDJ68040.1 - 2.2e-05 25.1 0.6 3.3 8.7 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Cnd1 PF12717.7 CDJ68041.1 - 0.00023 21.3 2.0 0.063 13.3 0.1 4.1 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.8 CDJ68041.1 - 0.02 14.9 0.0 2.3 8.2 0.0 3.0 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central HEAT PF02985.22 CDJ68041.1 - 0.025 14.8 0.2 0.025 14.8 0.2 5.5 6 0 0 6 6 6 0 HEAT repeat Fer2_2 PF01799.20 CDJ68041.1 - 0.049 13.7 0.0 0.18 11.8 0.0 2.0 1 0 0 1 1 1 0 [2Fe-2S] binding domain Hexokinase_2 PF03727.16 CDJ68041.1 - 0.17 11.3 4.4 0.14 11.5 0.6 2.6 4 0 0 4 4 4 0 Hexokinase HEAT_2 PF13646.6 CDJ68041.1 - 6.9 7.1 15.4 1.7 9.0 7.1 3.8 3 1 0 3 3 3 0 HEAT repeats RIX1 PF08167.12 CDJ68042.1 - 0.00058 19.7 0.4 0.0016 18.2 0.1 2.0 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis TPH PF13868.6 CDJ68043.1 - 1.7e-11 43.3 148.3 1.7e-11 43.3 148.3 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Coatomer_WDAD PF04053.14 CDJ68044.1 - 0.02 13.9 0.5 0.025 13.6 0.5 1.1 1 0 0 1 1 1 0 Coatomer WD associated region NAGLU PF05089.12 CDJ68045.1 - 0.005 15.8 0.0 0.0097 14.9 0.0 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Histone PF00125.24 CDJ68048.1 - 2.9e-17 63.2 0.0 4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CDJ68048.1 - 6.5e-11 41.8 0.1 1.3e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CDJ68048.1 - 8.3e-05 22.8 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.27 CDJ68050.1 - 3.4e-57 190.4 10.2 2.5e-23 81.8 0.0 5.1 5 0 0 5 5 5 4 Mitochondrial carrier protein zf-C2H2_2 PF12756.7 CDJ68051.1 - 2.7e-17 62.9 1.1 2.7e-17 62.9 1.1 3.1 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CDJ68051.1 - 4.9 7.6 6.5 6.9 7.1 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AMP-binding PF00501.28 CDJ68052.1 - 1.9e-21 76.2 0.0 7.5e-20 70.9 0.0 2.8 2 1 0 2 2 2 1 AMP-binding enzyme DALR_1 PF05746.15 CDJ68053.1 - 2.7e-12 46.9 0.0 2.7e-12 46.9 0.0 4.1 3 1 0 3 3 2 1 DALR anticodon binding domain SR-25 PF10500.9 CDJ68053.1 - 2.7e-05 23.9 66.5 0.00024 20.8 8.6 5.0 5 0 0 5 5 5 2 Nuclear RNA-splicing-associated protein MID_MedPIWI PF18296.1 CDJ68053.1 - 0.00037 20.4 38.9 0.048 13.5 0.8 4.4 4 0 0 4 4 4 3 MID domain of medPIWI Spt20 PF12090.8 CDJ68053.1 - 0.00047 19.9 5.0 0.00047 19.9 5.0 5.2 4 1 0 4 4 3 2 Spt20 family Androgen_recep PF02166.16 CDJ68053.1 - 0.0032 16.4 2.1 0.0032 16.4 2.1 6.9 4 2 3 7 7 3 1 Androgen receptor DUF3807 PF12720.7 CDJ68053.1 - 0.0071 16.6 47.2 0.074 13.3 3.7 4.3 4 0 0 4 4 4 3 Protein of unknown function (DUF3807) Myc_N PF01056.18 CDJ68053.1 - 0.0087 16.0 0.5 0.0087 16.0 0.5 4.4 2 1 1 4 4 2 1 Myc amino-terminal region RskA PF10099.9 CDJ68053.1 - 0.017 15.4 0.5 0.017 15.4 0.5 6.1 3 2 1 4 4 2 0 Anti-sigma-K factor rskA CCSAP PF15748.5 CDJ68053.1 - 0.017 15.3 65.6 0.28 11.3 3.8 4.1 4 0 0 4 4 4 0 Centriole, cilia and spindle-associated FmiP_Thoc5 PF09766.9 CDJ68053.1 - 0.04 13.2 39.3 0.16 11.2 2.4 3.5 4 0 0 4 4 3 0 Fms-interacting protein/Thoc5 Velvet PF11754.8 CDJ68053.1 - 0.064 13.2 45.6 0.58 10.1 10.1 4.2 4 0 0 4 4 4 0 Velvet factor CDC45 PF02724.14 CDJ68053.1 - 0.071 11.4 28.8 0.19 10.0 11.0 3.4 3 0 0 3 3 3 0 CDC45-like protein Peptidase_S49_N PF08496.10 CDJ68053.1 - 0.15 12.2 31.6 0.16 12.0 11.0 3.9 4 0 0 4 4 4 0 Peptidase family S49 N-terminal Connexin PF00029.19 CDJ68053.1 - 0.46 10.2 31.6 5 6.8 14.8 3.3 3 0 0 3 3 3 0 Connexin SpoIIP PF07454.11 CDJ68053.1 - 1.4 8.3 43.2 0.44 10.0 4.0 3.3 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDJ68053.1 - 1.5 8.5 40.2 0.15 11.8 12.1 3.9 4 0 0 4 4 4 0 Ryanodine Receptor TM 4-6 SUIM_assoc PF16619.5 CDJ68053.1 - 2.1 8.5 0.0 2.1 8.5 0.0 9.5 4 4 1 5 5 2 0 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 CDJ68053.1 - 5.3 7.4 50.8 0.059 13.8 12.6 4.4 4 1 0 4 4 3 0 Enhancer of polycomb-like PAP_RNA-bind PF04926.15 CDJ68053.1 - 7.2 6.2 28.7 2.4 7.8 2.2 3.7 3 0 0 3 3 3 0 Poly(A) polymerase predicted RNA binding domain CENP-N PF05238.13 CDJ68053.1 - 9.3 5.4 27.4 0.14 11.5 2.5 3.1 3 0 0 3 3 3 0 Kinetochore protein CHL4 like DUF2722 PF10846.8 CDJ68054.1 - 0.002 17.2 5.1 0.002 17.2 5.1 11.6 3 2 2 6 6 6 1 Protein of unknown function (DUF2722) DUF3336 PF11815.8 CDJ68056.1 - 1.8e-15 56.8 0.1 3.2e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CDJ68056.1 - 1.1e-12 48.5 0.4 1.1e-12 48.5 0.4 3.9 3 2 0 3 3 3 1 Patatin-like phospholipase LEP503 PF15221.6 CDJ68056.1 - 0.041 14.2 0.0 0.041 14.2 0.0 2.3 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 SOG2 PF10428.9 CDJ68056.1 - 0.19 10.9 32.8 0.3 10.2 32.8 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_L2_C PF03947.18 CDJ68058.1 - 3.7e-17 62.7 0.0 7.5e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CDJ68058.1 - 5.7e-06 26.2 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SR-25 PF10500.9 CDJ68058.1 - 0.0065 16.1 24.4 0.11 12.1 17.2 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein AUX_IAA PF02309.16 CDJ68058.1 - 0.37 10.6 7.9 0.66 9.8 7.9 1.4 1 0 0 1 1 1 0 AUX/IAA family SLC12 PF03522.15 CDJ68058.1 - 0.5 9.3 18.5 0.9 8.5 18.5 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF572 PF04502.13 CDJ68058.1 - 1.1 8.8 19.3 2.3 7.8 19.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAM60A PF15396.6 CDJ68058.1 - 1.5 8.8 15.8 0.41 10.6 12.9 1.5 2 0 0 2 2 2 0 Protein Family FAM60A DUF2151 PF10221.9 CDJ68058.1 - 3.2 6.2 13.6 4.2 5.8 13.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Presenilin PF01080.17 CDJ68058.1 - 3.8 6.2 26.3 7.1 5.3 26.3 1.3 1 0 0 1 1 1 0 Presenilin PIP5K PF01504.18 CDJ68058.1 - 8.8 5.5 14.6 17 4.5 14.6 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase eIF_4EBP PF05456.11 CDJ68058.1 - 8.9 6.3 13.7 11 6.0 2.2 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF1180 PF06679.12 CDJ68059.1 - 0.033 14.6 4.4 0.041 14.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4050 PF13259.6 CDJ68059.1 - 0.036 14.4 4.1 0.038 14.3 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) EBP50_C PF09007.11 CDJ68059.1 - 0.056 14.4 6.1 0.069 14.1 6.1 1.1 1 0 0 1 1 1 0 EBP50, C-terminal DUF4366 PF14283.6 CDJ68059.1 - 0.094 12.8 0.7 0.12 12.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Lin-8 PF03353.15 CDJ68059.1 - 0.14 11.7 4.6 0.17 11.4 4.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pex14_N PF04695.13 CDJ68059.1 - 0.14 12.8 9.6 0.14 12.8 9.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Roughex PF06020.11 CDJ68059.1 - 0.14 11.2 12.5 0.35 9.9 0.5 2.0 1 1 1 2 2 2 0 Drosophila roughex protein CCDC53 PF10152.9 CDJ68059.1 - 0.28 11.6 6.4 0.32 11.4 6.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Orf78 PF06024.12 CDJ68059.1 - 0.34 11.2 4.2 0.47 10.8 4.2 1.1 1 0 0 1 1 1 0 Orf78 (ac78) Presenilin PF01080.17 CDJ68059.1 - 0.94 8.2 6.4 1 8.1 6.4 1.2 1 0 0 1 1 1 0 Presenilin Chorion_2 PF03964.15 CDJ68059.1 - 0.95 10.3 16.1 1.6 9.6 16.1 1.4 1 1 0 1 1 1 0 Chorion family 2 Kei1 PF08552.11 CDJ68059.1 - 1.5 8.7 8.0 1.8 8.4 8.0 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TFIIA PF03153.13 CDJ68059.1 - 2.1 8.2 17.6 2 8.3 17.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RVP_2 PF08284.11 CDJ68060.1 - 1.9e-10 40.7 0.0 2.7e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ68060.1 - 5.5e-09 36.6 0.0 1.2e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ68060.1 - 5.5e-08 33.3 0.0 1.5e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ68060.1 - 0.0089 16.3 0.0 0.034 14.4 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ68060.1 - 0.075 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DEADboxA PF12343.8 CDJ68060.1 - 0.24 12.0 2.7 0.51 10.9 2.7 1.5 1 0 0 1 1 1 0 Cold shock protein DEAD box A SR-25 PF10500.9 CDJ68061.1 - 0.00029 20.5 44.2 0.00097 18.8 44.2 1.8 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 CDJ68061.1 - 0.12 10.4 15.1 0.22 9.6 15.1 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen PAP1 PF08601.10 CDJ68061.1 - 3.2 7.4 25.7 4 7.1 25.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 RXLR PF16810.5 CDJ68061.1 - 8.8 6.8 24.9 9.4 6.7 12.4 2.2 1 1 1 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity DUF4820 PF16091.5 CDJ68062.1 - 3 7.1 15.2 3.6 6.9 15.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) MMU163 PF17119.5 CDJ68062.1 - 3.5 6.7 13.0 3.9 6.6 13.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis FAM176 PF14851.6 CDJ68062.1 - 8.2 6.1 12.1 9.8 5.8 12.1 1.2 1 0 0 1 1 1 0 FAM176 family RabGAP-TBC PF00566.18 CDJ68062.1 - 8.2 6.0 16.2 9.6 5.8 16.2 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain MPM1 PF17234.2 CDJ68062.1 - 9.3 6.5 24.3 11 6.2 24.3 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 SR-25 PF10500.9 CDJ68063.1 - 0.0017 18.1 12.1 0.0017 18.1 12.1 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF2721 PF11026.8 CDJ68063.1 - 0.054 13.4 0.7 0.054 13.4 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) UPF0093 PF03653.13 CDJ68063.1 - 0.087 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) UCR_Fe-S_N PF10399.9 CDJ68063.1 - 0.092 12.1 0.4 0.092 12.1 0.4 3.8 2 1 0 2 2 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF2157 PF09925.9 CDJ68063.1 - 0.094 12.5 0.5 0.094 12.5 0.5 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Peptidase_S64 PF08192.11 CDJ68063.1 - 0.15 10.5 6.0 0.16 10.4 6.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Trp_oprn_chp PF09534.10 CDJ68063.1 - 0.56 10.0 32.4 0.83 9.4 4.5 2.1 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SLATT_1 PF18181.1 CDJ68063.1 - 1.1 9.2 23.8 1.8 8.5 1.9 2.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 UCR_TM PF02921.14 CDJ68063.1 - 1.2 9.7 0.1 1.2 9.7 0.1 3.5 3 1 1 4 4 3 0 Ubiquinol cytochrome reductase transmembrane region DUF3325 PF11804.8 CDJ68063.1 - 1.4 9.1 26.2 3.3 7.9 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Cyt_bd_oxida_II PF02322.15 CDJ68063.1 - 3.4 7.0 8.9 14 4.9 7.1 2.0 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II RskA PF10099.9 CDJ68063.1 - 6.7 7.0 42.2 0.52 10.6 9.6 2.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA PET117 PF15786.5 CDJ68064.1 - 0.00015 22.0 8.8 0.00019 21.6 8.8 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Transposase_1 PF01359.18 CDJ68064.1 - 0.0021 17.8 0.4 0.0021 17.8 0.4 2.0 1 1 1 2 2 2 1 Transposase (partial DDE domain) UvrA_DNA-bind PF17755.1 CDJ68064.1 - 0.0034 17.7 0.2 0.004 17.5 0.2 1.3 1 1 0 1 1 1 1 UvrA DNA-binding domain Presenilin PF01080.17 CDJ68064.1 - 1.4 7.6 5.3 1.5 7.5 5.3 1.0 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ68064.1 - 3 7.4 22.1 3 7.4 22.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF4407 PF14362.6 CDJ68064.1 - 3.3 7.0 8.7 3.5 6.9 8.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ68064.1 - 7 6.5 19.4 7.1 6.5 19.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IMUP PF15761.5 CDJ68065.1 - 0.034 14.8 0.8 0.04 14.6 0.8 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ68065.1 - 0.14 11.8 2.6 0.16 11.6 2.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPC25 PF06703.11 CDJ68065.1 - 0.2 11.4 0.9 0.99 9.2 0.4 1.9 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) TFIIA PF03153.13 CDJ68066.1 - 0.0028 17.7 18.7 0.003 17.6 18.7 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit P16-Arc PF04699.14 CDJ68066.1 - 0.029 14.8 11.6 0.091 13.3 6.5 2.2 1 1 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DDHD PF02862.17 CDJ68066.1 - 0.096 12.8 4.0 0.1 12.7 4.0 1.2 1 0 0 1 1 1 0 DDHD domain 7TM_GPCR_Srv PF10323.9 CDJ68066.1 - 0.2 11.0 1.1 0.28 10.5 1.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv PVL_ORF50 PF07768.11 CDJ68066.1 - 0.25 11.7 7.9 1.1 9.6 6.7 2.3 1 1 1 2 2 2 0 PVL ORF-50-like family Ndc1_Nup PF09531.10 CDJ68066.1 - 0.49 9.0 5.6 0.55 8.9 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hydin_ADK PF17213.3 CDJ68066.1 - 0.81 9.9 7.7 1.2 9.4 7.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MAT1 PF06391.13 CDJ68066.1 - 0.84 9.4 17.4 1.5 8.6 17.4 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Dopey_N PF04118.14 CDJ68066.1 - 0.85 8.7 8.0 1.5 7.9 8.0 1.4 1 1 0 1 1 1 0 Dopey, N-terminal FAM60A PF15396.6 CDJ68066.1 - 0.95 9.4 6.5 1.4 8.9 6.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Baculo_PP31 PF05311.11 CDJ68066.1 - 1 8.8 7.8 1.6 8.2 7.8 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Phage_GPO PF05929.11 CDJ68066.1 - 1.1 8.8 12.1 1.5 8.4 12.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ALMT PF11744.8 CDJ68066.1 - 1.9 7.2 5.8 2.2 7.0 5.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PA26 PF04636.13 CDJ68066.1 - 3.4 6.5 10.0 4.4 6.1 10.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Connexin PF00029.19 CDJ68066.1 - 3.9 7.1 6.1 5.4 6.7 6.1 1.2 1 0 0 1 1 1 0 Connexin DUF3270 PF11674.8 CDJ68066.1 - 4 7.7 6.3 7.4 6.8 5.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3270) LMBR1 PF04791.16 CDJ68066.1 - 4.8 6.0 5.6 5.1 5.9 5.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FAD-SLDH PF12318.8 CDJ68066.1 - 7.7 6.6 12.8 75 3.3 0.0 2.3 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Presenilin PF01080.17 CDJ68066.1 - 8.7 5.0 10.7 11 4.7 10.7 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ68066.1 - 9.1 6.3 9.7 13 5.7 9.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Activator_LAG-3 PF11498.8 CDJ68067.1 - 0.013 14.5 18.3 0.018 14.1 18.3 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Stevor PF17410.2 CDJ68067.1 - 0.052 13.1 4.1 0.066 12.8 4.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Miga PF10265.9 CDJ68067.1 - 0.35 9.8 10.5 0.38 9.7 10.5 1.1 1 0 0 1 1 1 0 Mitoguardin FSA_C PF10479.9 CDJ68067.1 - 0.4 8.8 10.0 0.47 8.5 10.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NACHT_N PF17100.5 CDJ68067.1 - 1.2 8.9 13.1 1.5 8.6 13.1 1.1 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Spt20 PF12090.8 CDJ68067.1 - 1.4 8.5 11.2 1.9 8.1 11.2 1.1 1 0 0 1 1 1 0 Spt20 family Draxin PF15550.6 CDJ68067.1 - 1.6 8.5 8.0 2.1 8.1 8.0 1.1 1 0 0 1 1 1 0 Draxin Med15 PF09606.10 CDJ68067.1 - 7.6 5.1 16.0 8.3 5.0 16.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ACPS PF01648.20 CDJ68068.1 - 2.3e-13 50.3 0.1 1.2e-12 47.9 0.1 2.2 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily UPF0054 PF02130.17 CDJ68068.1 - 0.0052 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Spt20 PF12090.8 CDJ68068.1 - 4.9 6.7 11.9 7.4 6.1 0.7 2.4 2 1 0 2 2 2 0 Spt20 family RskA PF10099.9 CDJ68069.1 - 0.073 13.4 32.8 0.22 11.8 4.7 3.1 1 1 2 3 3 3 0 Anti-sigma-K factor rskA INSIG PF07281.12 CDJ68069.1 - 0.14 11.8 0.2 0.14 11.8 0.2 3.1 2 1 0 3 3 3 0 Insulin-induced protein (INSIG) N6_N4_Mtase PF01555.18 CDJ68069.1 - 3.2 7.4 6.9 52 3.4 7.0 2.5 1 1 0 1 1 1 0 DNA methylase Hamartin PF04388.12 CDJ68069.1 - 3.3 6.3 26.8 4.1 5.9 26.8 1.1 1 0 0 1 1 1 0 Hamartin protein ETRAMP PF09716.10 CDJ68070.1 - 0.096 12.8 8.4 0.97 9.5 1.4 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PRIMA1 PF16101.5 CDJ68070.1 - 0.31 11.1 5.2 0.45 10.6 5.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4366 PF14283.6 CDJ68070.1 - 0.34 10.9 8.4 0.89 9.6 8.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) UCR_TM PF02921.14 CDJ68070.1 - 1.9 9.0 11.3 5.7 7.5 1.7 2.2 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region TrbC PF04956.13 CDJ68070.1 - 4.6 7.5 14.4 3.2 8.0 2.0 2.1 2 0 0 2 2 2 0 TrbC/VIRB2 family Ten_N PF06484.12 CDJ68070.1 - 5 6.9 11.6 5.5 6.8 11.6 1.0 1 0 0 1 1 1 0 Teneurin Intracellular Region YL1 PF05764.13 CDJ68070.1 - 5.3 7.1 10.5 6 6.9 10.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF4551 PF15087.6 CDJ68070.1 - 8.7 5.0 6.2 8.9 5.0 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Kelch_5 PF13854.6 CDJ68071.1 - 2.3e-22 78.5 0.6 9.6e-07 28.7 0.0 5.1 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 CDJ68071.1 - 1.3e-16 60.4 0.4 8.1e-07 29.0 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ68071.1 - 5.2e-15 54.7 13.9 6.5e-07 29.1 0.0 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 CDJ68071.1 - 1.3e-14 54.0 17.0 0.00018 21.7 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CDJ68071.1 - 4.5e-14 51.7 0.0 6.2e-06 25.7 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDJ68071.1 - 2.5e-07 30.7 0.6 0.14 12.5 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Spt20 PF12090.8 CDJ68071.1 - 2.8 7.5 92.5 0.068 12.8 31.0 4.3 4 0 0 4 4 4 0 Spt20 family Kelch_5 PF13854.6 CDJ68072.1 - 3.3e-29 100.3 0.5 6.8e-09 35.5 0.1 4.3 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 CDJ68072.1 - 3.5e-29 100.6 1.3 3.9e-09 36.4 0.0 4.1 2 2 2 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ68072.1 - 1.8e-26 91.8 1.0 9.7e-07 28.9 0.0 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ68072.1 - 6.2e-25 86.6 0.2 3.4e-07 30.3 0.2 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 CDJ68072.1 - 4.3e-21 74.2 2.0 3.8e-07 29.6 0.1 4.6 4 1 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 CDJ68072.1 - 1.3e-19 69.4 1.8 4e-08 32.9 0.1 4.4 4 0 0 4 4 4 4 Kelch motif Ribosomal_S25 PF03297.15 CDJ68073.1 - 4.8e-36 123.0 0.7 8.6e-36 122.2 0.7 1.4 1 0 0 1 1 1 1 S25 ribosomal protein DEAD PF00270.29 CDJ68074.1 - 1e-30 106.8 1.7 3.1e-30 105.3 1.7 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ68074.1 - 2.3e-21 76.2 0.0 1.1e-20 74.1 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ68074.1 - 0.0015 18.5 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ68074.1 - 0.0029 17.9 2.0 0.012 15.9 0.7 2.7 2 1 0 2 2 2 1 AAA domain SIS PF01380.22 CDJ68074.1 - 0.0049 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 SIS domain DUF2075 PF09848.9 CDJ68074.1 - 0.12 11.5 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MRPL52 PF18699.1 CDJ68074.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.7 3 0 0 3 3 3 0 Mitoribosomal protein mL52 NACHT PF05729.12 CDJ68074.1 - 3.7 7.4 7.2 12 5.7 7.2 1.9 1 1 0 1 1 1 0 NACHT domain Phage_integrase PF00589.22 CDJ68075.1 - 3.1e-10 40.1 0.0 7.2e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family zinc_ribbon_2 PF13240.6 CDJ68075.1 - 2.4e-05 23.9 1.5 5.1e-05 22.8 1.5 1.6 1 0 0 1 1 1 1 zinc-ribbon domain SAP PF02037.27 CDJ68075.1 - 2.8e-05 23.7 0.3 7.2e-05 22.4 0.3 1.7 1 0 0 1 1 1 1 SAP domain DZR PF12773.7 CDJ68075.1 - 5.1e-05 23.2 0.9 0.00012 22.0 0.9 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 CDJ68075.1 - 0.00058 20.6 0.9 0.0012 19.6 0.9 1.5 1 0 0 1 1 1 1 zinc-ribbon family PLATZ PF04640.14 CDJ68075.1 - 0.006 17.2 0.6 0.013 16.1 0.6 1.5 1 0 0 1 1 1 1 PLATZ transcription factor zf-ribbon_3 PF13248.6 CDJ68075.1 - 0.008 15.6 1.1 0.019 14.4 1.1 1.6 1 0 0 1 1 1 1 zinc-ribbon domain HypA PF01155.19 CDJ68075.1 - 0.072 13.1 0.4 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NOB1_Zn_bind PF08772.11 CDJ68075.1 - 0.18 12.0 1.6 0.44 10.7 1.6 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.11 CDJ68075.1 - 0.2 11.3 0.1 0.2 11.3 0.1 2.8 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc-ribbon_6 PF10005.9 CDJ68075.1 - 0.35 11.6 2.2 0.45 11.2 0.4 2.0 2 0 0 2 2 2 0 zinc-ribbon domain UQ_con PF00179.26 CDJ68077.1 - 1e-23 83.5 0.0 1.8e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TFIIA PF03153.13 CDJ68077.1 - 1.1 9.2 8.9 1.8 8.5 8.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Chromo PF00385.24 CDJ68078.1 - 8.2e-13 48.1 0.0 1.7e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PKS_DE PF18369.1 CDJ68078.1 - 0.69 10.5 6.1 53 4.5 4.2 3.1 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain RVT_1 PF00078.27 CDJ68079.1 - 2e-21 76.5 0.0 3.3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MBOAT PF03062.19 CDJ68080.1 - 3.7e-24 85.7 19.1 5.2e-24 85.2 19.1 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CDJ68080.1 - 4.6e-06 26.8 5.2 1.9e-05 24.8 5.2 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Spt20 PF12090.8 CDJ68080.1 - 0.91 9.1 15.5 1.1 8.8 15.5 1.1 1 0 0 1 1 1 0 Spt20 family Methyltransf_10 PF05971.12 CDJ68082.1 - 5.2e-60 203.3 0.2 1.9e-38 132.5 0.0 4.0 3 1 0 3 3 3 2 RNA methyltransferase Methyltransf_25 PF13649.6 CDJ68082.1 - 0.0067 17.1 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ68082.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SR-25 PF10500.9 CDJ68082.1 - 0.039 13.6 38.1 0.045 13.4 16.9 2.6 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Methyltransf_11 PF08241.12 CDJ68082.1 - 0.062 14.0 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ68082.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ68082.1 - 0.099 13.4 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF755 PF05501.11 CDJ68082.1 - 0.58 10.4 32.7 0.22 11.8 11.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF4667 PF15700.5 CDJ68082.1 - 0.64 10.1 10.8 2.8 8.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ68082.1 - 1.7 8.5 10.7 4.7 7.0 0.5 2.4 2 0 0 2 2 2 0 SPX domain Secretin_N_2 PF07655.13 CDJ68082.1 - 2.5 8.7 17.6 0.3 11.7 5.0 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain FAM104 PF15434.6 CDJ68082.1 - 3.1 8.4 15.6 7.5 7.2 1.6 2.5 2 0 0 2 2 2 0 Family 104 TFIIA PF03153.13 CDJ68083.1 - 0.09 12.8 8.0 0.09 12.8 8.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dehydrin PF00257.19 CDJ68083.1 - 0.31 11.6 14.2 0.39 11.3 14.2 1.3 1 1 0 1 1 1 0 Dehydrin RskA PF10099.9 CDJ68084.1 - 0.00045 20.6 0.0 0.00045 20.6 0.0 4.2 2 1 0 4 4 4 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ68084.1 - 0.0043 17.6 27.3 0.0079 16.8 5.1 3.1 3 0 0 3 3 3 2 60s Acidic ribosomal protein STIMATE PF12400.8 CDJ68085.1 - 2.7e-16 60.3 0.2 3.6e-16 59.8 0.2 1.1 1 0 0 1 1 1 1 STIMATE family Retrotrans_gag PF03732.17 CDJ68087.1 - 1.1e-06 28.8 0.0 2.1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 CDJ68087.1 - 2.7e-05 24.1 2.6 2.7e-05 24.1 2.6 2.9 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ68087.1 - 0.022 14.6 0.8 0.022 14.6 0.8 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ68087.1 - 0.028 14.4 0.3 0.028 14.4 0.3 2.7 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ68087.1 - 0.23 11.3 10.5 0.23 11.3 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ68087.1 - 7.2 6.4 9.3 1.6 8.5 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle ORC_WH_C PF18137.1 CDJ68088.1 - 0.0069 16.5 15.0 0.0097 16.0 15.0 1.3 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal Tim54 PF11711.8 CDJ68088.1 - 0.99 8.1 14.9 1 8.1 14.9 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 CDJ68088.1 - 1.4 9.0 13.2 1.6 8.9 13.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CDJ68088.1 - 2 7.1 23.1 2.1 7.0 23.1 1.0 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ68088.1 - 2.2 7.2 18.1 2.3 7.1 18.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Asp-B-Hydro_N PF05279.11 CDJ68088.1 - 2.6 8.1 10.7 2.9 7.9 10.7 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SpoIIP PF07454.11 CDJ68088.1 - 2.7 7.4 18.9 3 7.2 18.9 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NARP1 PF12569.8 CDJ68088.1 - 2.8 6.8 16.1 2.9 6.7 16.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ALMT PF11744.8 CDJ68088.1 - 2.9 6.6 14.2 3 6.6 14.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Pex14_N PF04695.13 CDJ68088.1 - 3.5 8.3 31.3 4.4 7.9 31.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gti1_Pac2 PF09729.9 CDJ68088.1 - 3.9 7.5 17.1 4.5 7.3 17.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family NPR3 PF03666.13 CDJ68088.1 - 4 6.1 18.5 4.2 6.1 18.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MDM10 PF12519.8 CDJ68088.1 - 4.1 6.2 16.6 4.4 6.1 16.6 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FAM60A PF15396.6 CDJ68088.1 - 4.3 7.3 15.5 4.8 7.1 15.5 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF913 PF06025.12 CDJ68088.1 - 4.6 6.1 11.7 4.8 6.1 11.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM176 PF14851.6 CDJ68088.1 - 4.6 6.9 9.5 6.7 6.4 9.5 1.4 1 0 0 1 1 1 0 FAM176 family Kei1 PF08552.11 CDJ68088.1 - 4.8 7.0 13.4 5.1 6.9 13.4 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DDHD PF02862.17 CDJ68088.1 - 5.4 7.1 16.1 6.5 6.8 16.1 1.2 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 CDJ68088.1 - 5.6 6.9 18.4 6.7 6.7 18.4 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ68088.1 - 6 6.6 20.4 6.7 6.5 20.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S64 PF08192.11 CDJ68088.1 - 6.2 5.2 16.7 7 5.0 16.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 Endostatin PF06482.11 CDJ68088.1 - 6.6 6.1 20.5 7.2 6.0 20.5 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4746 PF15928.5 CDJ68088.1 - 6.6 6.1 12.6 7.6 5.9 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Membralin PF09746.9 CDJ68088.1 - 6.9 5.6 11.7 7.3 5.5 11.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein DAG_kinase_N PF14513.6 CDJ68088.1 - 7.1 6.8 20.1 8.2 6.6 20.1 1.0 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus PTPRCAP PF15713.5 CDJ68088.1 - 7.8 6.8 20.7 9.5 6.5 20.7 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Sec62 PF03839.16 CDJ68088.1 - 8 5.9 15.3 8.9 5.8 15.3 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 NST1 PF13945.6 CDJ68088.1 - 8.2 6.5 26.2 11 6.1 26.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4638 PF15472.6 CDJ68088.1 - 8.3 6.1 16.8 8.9 6.0 16.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Hydin_ADK PF17213.3 CDJ68088.1 - 8.9 6.5 16.8 11 6.2 16.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CDC45 PF02724.14 CDJ68088.1 - 9.1 4.4 16.9 10 4.3 16.9 1.0 1 0 0 1 1 1 0 CDC45-like protein YABBY PF04690.13 CDJ68088.1 - 9.8 6.7 15.5 11 6.5 15.5 1.1 1 0 0 1 1 1 0 YABBY protein RLI PF04068.15 CDJ68089.1 - 4.5e-07 29.6 0.1 9.4e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Aldedh PF00171.22 CDJ68090.1 - 7e-32 110.5 0.0 7.6e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-RVT PF13966.6 CDJ68091.1 - 8.5e-07 29.6 0.5 3.2e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Prp31_C PF09785.9 CDJ68092.1 - 1.5e-23 84.0 6.9 1.1e-20 74.8 6.9 2.4 1 1 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.18 CDJ68092.1 - 1.5e-08 34.4 0.2 2.7e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Collagen PF01391.18 CDJ68093.1 - 3.8e-05 23.4 19.9 3.8e-05 23.4 19.9 4.0 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Macoilin PF09726.9 CDJ68093.1 - 4.6 5.7 4.0 9.9 4.6 4.0 1.5 1 0 0 1 1 1 0 Macoilin family RskA PF10099.9 CDJ68094.1 - 3.8e-05 24.1 1.6 3.8e-05 24.1 1.6 6.3 1 1 4 5 5 5 2 Anti-sigma-K factor rskA Sporozoite_P67 PF05642.11 CDJ68094.1 - 0.0064 14.7 0.0 0.0064 14.7 0.0 2.8 2 1 1 3 3 3 1 Sporozoite P67 surface antigen SR-25 PF10500.9 CDJ68095.1 - 1.1 8.9 38.9 0.53 9.8 15.7 3.4 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein CiPC PF15800.5 CDJ68096.1 - 0.18 11.5 9.8 0.24 11.1 9.8 1.1 1 0 0 1 1 1 0 Clock interacting protein circadian Secretin_N_2 PF07655.13 CDJ68096.1 - 2 9.0 16.2 4.5 7.9 4.4 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Macoilin PF09726.9 CDJ68096.1 - 2.1 6.8 7.8 2.6 6.5 7.8 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ68096.1 - 2.3 7.0 7.1 2.6 6.8 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2076 PF09849.9 CDJ68096.1 - 6.1 6.8 12.7 9.3 6.2 12.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L4 PF00573.22 CDJ68097.1 - 7.8e-28 97.5 0.0 7.8e-28 97.5 0.0 1.9 2 1 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CDJ68097.1 - 1.4e-17 63.5 8.7 1.4e-17 63.5 8.7 2.2 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain NAC PF01849.18 CDJ68098.1 - 2.5e-12 46.6 0.0 5.7e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 NAC domain DUF1664 PF07889.12 CDJ68098.1 - 0.23 11.5 5.9 0.52 10.4 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Succ_CoA_lig PF13607.6 CDJ68098.1 - 0.24 11.2 4.2 0.074 12.9 0.9 1.8 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain YbjQ_1 PF01906.17 CDJ68098.1 - 0.6 10.8 3.3 0.29 11.8 1.1 1.7 2 0 0 2 2 2 0 Putative heavy-metal-binding Nitrate_red_del PF02613.15 CDJ68098.1 - 0.63 10.0 7.9 2 8.4 7.9 1.9 1 1 0 1 1 1 0 Nitrate reductase delta subunit Sigma70_ner PF04546.13 CDJ68098.1 - 1.3 8.9 9.7 0.26 11.2 2.5 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region LPP20 PF02169.16 CDJ68098.1 - 6.6 7.2 13.3 0.43 11.0 3.8 2.7 2 1 1 3 3 3 0 LPP20 lipoprotein Thioredoxin_6 PF13848.6 CDJ68099.1 - 1.1e-05 25.4 0.0 0.00017 21.6 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin PF00085.20 CDJ68099.1 - 0.062 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Apt1 PF10351.9 CDJ68100.1 - 0.035 13.0 5.7 0.044 12.7 5.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ68100.1 - 0.11 12.4 7.8 0.15 12.0 7.8 1.2 1 0 0 1 1 1 0 SPX domain Secretin_N_2 PF07655.13 CDJ68100.1 - 0.76 10.4 28.7 0.1 13.2 13.3 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain CCDC106 PF15794.5 CDJ68100.1 - 1.5 8.5 13.0 6.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF2722 PF10846.8 CDJ68101.1 - 0.0048 15.9 23.4 0.0063 15.5 23.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ68101.1 - 0.14 12.1 40.9 0.16 12.0 40.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDRGK PF09756.9 CDJ68101.1 - 0.18 11.4 13.7 0.18 11.4 13.7 1.1 1 0 0 1 1 1 0 DDRGK domain MMR1 PF08505.10 CDJ68101.1 - 0.36 11.1 21.8 0.41 10.9 21.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Draxin PF15550.6 CDJ68101.1 - 0.82 9.5 13.8 0.91 9.3 13.8 1.0 1 0 0 1 1 1 0 Draxin eIF-3_zeta PF05091.12 CDJ68101.1 - 1.5 7.7 19.5 1.5 7.7 19.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ68101.1 - 1.9 6.3 11.9 1.9 6.3 11.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2052 PF09747.9 CDJ68101.1 - 2.5 8.2 16.8 3.1 7.9 16.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NST1 PF13945.6 CDJ68101.1 - 2.7 8.0 25.8 3.5 7.7 25.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Lin-8 PF03353.15 CDJ68101.1 - 3 7.3 18.6 3.4 7.2 18.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4683 PF15735.5 CDJ68101.1 - 3.7 7.1 14.6 4 7.0 14.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) UPF0560 PF10577.9 CDJ68101.1 - 4 5.8 20.0 3.8 5.9 20.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 OATP PF03137.20 CDJ68101.1 - 6.1 5.0 6.7 5.8 5.1 6.7 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family NPR3 PF03666.13 CDJ68101.1 - 6.1 5.5 15.4 6.7 5.4 15.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 WTX PF09422.10 CDJ68101.1 - 6.7 5.7 18.7 7.6 5.5 18.7 1.0 1 0 0 1 1 1 0 WTX protein Plasmodium_Vir PF05795.11 CDJ68101.1 - 7 6.0 12.7 6.9 6.0 12.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ribonuc_red_sm PF00268.21 CDJ68102.1 - 0.00015 21.3 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4667 PF15700.5 CDJ68103.1 - 0.0021 18.2 3.1 0.0021 18.2 3.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ68103.1 - 0.0074 16.2 1.1 0.0097 15.9 1.1 1.3 1 0 0 1 1 1 1 SPX domain Sina PF03145.16 CDJ68103.1 - 0.011 15.7 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 0 Seven in absentia protein family Apt1 PF10351.9 CDJ68103.1 - 0.061 12.2 1.0 0.077 11.8 1.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FtsJ PF01728.19 CDJ68105.1 - 3.9e-55 186.7 1.0 3.9e-55 186.7 1.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Sin_N PF04801.13 CDJ68105.1 - 0.0027 17.0 15.4 0.0027 17.0 15.4 2.3 2 1 0 2 2 1 1 Sin-like protein conserved region IER PF05760.12 CDJ68105.1 - 0.0035 17.7 9.5 0.0035 17.7 9.5 3.1 2 1 1 3 3 3 1 Immediate early response protein (IER) SUIM_assoc PF16619.5 CDJ68105.1 - 0.0056 16.7 3.9 0.0056 16.7 3.9 5.5 3 1 1 4 4 3 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ68105.1 - 0.0064 16.5 25.0 0.0064 16.5 25.0 2.5 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 CDJ68105.1 - 0.022 13.5 3.3 0.33 9.7 0.2 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Endostatin PF06482.11 CDJ68105.1 - 0.13 11.7 20.2 0.78 9.2 8.1 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin PAT1 PF09770.9 CDJ68105.1 - 2.3 6.4 36.4 0.37 9.0 18.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 LAP1C PF05609.12 CDJ68105.1 - 2.7 7.0 20.0 0.68 9.0 7.4 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) SLC12 PF03522.15 CDJ68105.1 - 3.7 6.4 18.1 1.8 7.5 0.9 2.1 2 0 0 2 2 2 0 Solute carrier family 12 DUF4569 PF15133.6 CDJ68105.1 - 4.2 7.0 19.3 0.98 9.1 6.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4569) Gti1_Pac2 PF09729.9 CDJ68105.1 - 4.5 7.3 19.2 0.13 12.4 3.9 2.3 2 1 0 2 2 2 0 Gti1/Pac2 family cwf18 PF08315.12 CDJ68105.1 - 4.6 7.9 23.8 0.84 10.3 7.1 2.6 3 1 0 3 3 2 0 cwf18 pre-mRNA splicing factor SpoIIP PF07454.11 CDJ68105.1 - 6.3 6.2 17.4 0.75 9.2 5.5 3.0 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) PA26 PF04636.13 CDJ68105.1 - 7.4 5.4 10.5 3.2 6.6 3.6 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Chromo PF00385.24 CDJ68108.1 - 1.3e-11 44.2 0.0 3.1e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_L14 PF00238.19 CDJ68110.1 - 1.2e-32 112.5 0.0 1.5e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PARG_cat PF05028.14 CDJ68111.1 - 3.3e-43 148.3 0.0 2.3e-21 76.5 0.0 3.6 4 0 0 4 4 4 2 Poly (ADP-ribose) glycohydrolase (PARG) URO-D PF01208.17 CDJ68112.1 - 9.9e-102 340.6 0.0 1.4e-101 340.2 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) zf_C2H2_6 PF18450.1 CDJ68112.1 - 2.4 8.0 4.3 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 Zinc Finger domain SCAI PF12070.8 CDJ68114.1 - 0.00035 19.6 8.3 0.066 12.1 1.0 2.3 2 0 0 2 2 2 2 Protein SCAI Pro_isomerase PF00160.21 CDJ68115.1 - 1.5e-48 165.1 0.0 1.7e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltransf_16 PF10294.9 CDJ68116.1 - 8.1e-05 22.4 0.1 0.14 11.9 0.0 2.5 2 1 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 CDJ68116.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CDJ68116.1 - 0.17 11.4 0.0 0.5 9.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain DUF2489 PF10675.9 CDJ68116.1 - 0.89 9.5 7.0 0.54 10.2 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) MarR_2 PF12802.7 CDJ68117.1 - 0.18 11.7 3.4 0.1 12.5 0.8 1.9 2 0 0 2 2 2 0 MarR family Macoilin PF09726.9 CDJ68117.1 - 0.29 9.6 5.6 0.39 9.2 5.6 1.1 1 0 0 1 1 1 0 Macoilin family Beach PF02138.18 CDJ68118.1 - 3.3e-73 246.5 0.0 6.2e-42 143.9 0.0 2.5 2 0 0 2 2 2 2 Beige/BEACH domain WD40 PF00400.32 CDJ68118.1 - 0.017 16.0 0.1 0.2 12.6 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Surface_antigen PF11054.8 CDJ68119.1 - 9.8e-23 81.1 6.7 1.1e-21 77.7 3.9 2.8 2 1 0 2 2 2 1 Sporozoite TA4 surface antigen GRP PF07172.11 CDJ68119.1 - 0.01 16.5 8.3 1.8 9.3 6.6 2.9 3 0 0 3 3 3 0 Glycine rich protein family Surface_antigen PF11054.8 CDJ68120.1 - 2.5e-24 86.3 0.4 5.7e-23 81.8 0.1 2.3 2 1 0 2 2 2 2 Sporozoite TA4 surface antigen FBPase PF00316.20 CDJ68121.1 - 5.8e-67 224.8 0.1 7.7e-67 224.4 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NucS PF01939.16 CDJ68121.1 - 0.1 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Endonuclease NucS NdhM PF10664.9 CDJ68121.1 - 0.15 12.3 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Proteasome PF00227.26 CDJ68122.1 - 3.4e-22 78.9 0.0 4e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.25 CDJ68123.1 - 0.003 17.0 0.0 0.0066 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain PTN_MK_C PF01091.18 CDJ68123.1 - 1.8 9.0 5.8 3.4 8.1 1.2 2.6 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain Not3 PF04065.15 CDJ68124.1 - 1.5e-56 191.4 14.2 1.5e-56 191.4 14.2 1.7 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CDJ68124.1 - 1.5e-33 115.6 0.1 4.1e-33 114.2 0.1 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Pkinase PF00069.25 CDJ68126.1 - 2.2e-70 237.1 0.0 3.6e-70 236.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ68126.1 - 3.6e-29 101.8 0.0 5.7e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ68126.1 - 0.0024 16.7 0.0 0.0075 15.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CDJ68126.1 - 0.006 16.5 0.2 0.02 14.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ68126.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 CDJ68126.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 PH domain Thioredoxin_8 PF13905.6 CDJ68127.1 - 4.3e-33 113.5 0.0 1.8e-26 92.3 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin PF00085.20 CDJ68127.1 - 3.3e-08 33.4 0.0 7.7e-07 29.1 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin Redoxin PF08534.10 CDJ68127.1 - 6e-08 32.5 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 CDJ68127.1 - 1.1e-07 32.2 0.0 3e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CDJ68127.1 - 6.7e-07 29.3 0.0 1.8e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family SCO1-SenC PF02630.14 CDJ68127.1 - 9.3e-05 22.3 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_7 PF13899.6 CDJ68127.1 - 0.045 13.9 0.0 0.32 11.2 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin-like DUF1180 PF06679.12 CDJ68128.1 - 0.077 13.4 0.2 0.077 13.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) XRN_M PF17846.1 CDJ68130.1 - 2e-08 33.6 0.3 0.00045 19.3 0.0 2.2 2 0 0 2 2 2 2 Xrn1 helical domain AAA_6 PF12774.7 CDJ68131.1 - 1.3e-131 438.5 0.0 6e-131 436.3 0.0 2.3 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ68131.1 - 2.1e-113 379.5 7.9 2.1e-113 379.5 7.9 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CDJ68131.1 - 2.8e-110 369.6 1.0 2.8e-110 369.6 1.0 4.7 4 1 1 5 5 5 2 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 CDJ68131.1 - 1.7e-67 226.8 0.1 1.7e-67 226.8 0.1 3.8 5 0 0 5 5 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 CDJ68131.1 - 4e-62 209.9 0.0 4.8e-61 206.3 0.0 3.0 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CDJ68131.1 - 5.5e-47 160.5 0.1 1.9e-46 158.7 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CDJ68131.1 - 2.4e-34 118.5 0.0 7.1e-28 97.3 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 CDJ68131.1 - 2.6e-33 115.5 11.5 4.3e-33 114.8 11.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CDJ68131.1 - 8.9e-33 113.4 0.0 2.2e-32 112.1 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ68131.1 - 2e-30 105.3 0.4 1.5e-29 102.5 0.0 2.9 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CDJ68131.1 - 4.4e-30 104.5 0.0 2.1e-11 44.0 0.0 6.9 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ68131.1 - 2.2e-15 57.3 0.1 0.0013 19.1 0.0 5.5 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 CDJ68131.1 - 1e-13 51.5 0.3 1.5e-11 44.5 0.3 3.1 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 CDJ68131.1 - 2e-12 47.5 2.2 0.0025 18.1 0.0 7.6 7 1 1 8 8 6 1 AAA domain AAA_16 PF13191.6 CDJ68131.1 - 2.6e-07 31.2 6.2 6.9 7.0 0.1 7.3 5 1 1 6 6 5 0 AAA ATPase domain AAA_18 PF13238.6 CDJ68131.1 - 3.4e-07 30.9 0.0 16 6.0 0.0 5.3 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 CDJ68131.1 - 1.6e-05 24.1 0.0 0.13 11.4 0.0 3.5 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_33 PF13671.6 CDJ68131.1 - 6.4e-05 23.1 4.2 0.46 10.6 0.0 5.0 5 0 0 5 5 4 1 AAA domain AAA_30 PF13604.6 CDJ68131.1 - 7.4e-05 22.6 1.4 5.7 6.6 0.0 5.2 5 0 0 5 5 5 0 AAA domain TelA PF05816.11 CDJ68131.1 - 0.00047 19.3 4.5 0.00047 19.3 4.5 3.4 2 0 0 2 2 1 1 Toxic anion resistance protein (TelA) AAA_25 PF13481.6 CDJ68131.1 - 0.00049 19.7 1.7 0.024 14.2 0.0 3.7 4 0 0 4 4 3 1 AAA domain IstB_IS21 PF01695.17 CDJ68131.1 - 0.0006 19.6 0.2 0.76 9.5 0.0 4.9 5 0 0 5 5 4 1 IstB-like ATP binding protein AAA_19 PF13245.6 CDJ68131.1 - 0.001 19.5 1.2 0.53 10.6 0.0 5.3 6 0 0 6 6 5 1 AAA domain Asn_synthase PF00733.21 CDJ68131.1 - 0.0029 17.3 0.2 0.0065 16.2 0.2 1.6 1 0 0 1 1 1 1 Asparagine synthase Rad17 PF03215.15 CDJ68131.1 - 0.0071 16.3 0.4 19 5.1 0.0 4.6 6 0 0 6 6 4 0 Rad17 P-loop domain TsaE PF02367.17 CDJ68131.1 - 0.0078 16.2 1.5 11 6.0 0.0 4.2 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_1 PF17857.1 CDJ68131.1 - 0.0094 16.2 0.0 0.027 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 CDJ68131.1 - 0.018 15.4 0.1 1.2e+02 3.1 0.0 4.9 4 0 0 4 4 4 0 RNA helicase RuvB_N PF05496.12 CDJ68131.1 - 0.024 14.4 0.1 1.8 8.3 0.0 3.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain MPS2 PF17060.5 CDJ68131.1 - 0.025 13.9 11.1 0.36 10.0 2.8 2.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 Mg_chelatase PF01078.21 CDJ68131.1 - 0.035 13.5 6.5 6 6.2 0.0 4.6 4 1 1 5 5 5 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 CDJ68131.1 - 0.048 13.2 0.2 0.43 10.2 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NBD94 PF16830.5 CDJ68131.1 - 0.12 12.8 6.1 0.11 13.0 2.4 2.9 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH ABC_tran PF00005.27 CDJ68131.1 - 0.36 11.3 9.5 17 5.9 0.0 5.9 7 0 0 7 7 4 0 ABC transporter LPP PF04728.13 CDJ68131.1 - 0.5 10.8 4.9 22 5.5 0.8 4.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Atg14 PF10186.9 CDJ68131.1 - 0.69 8.9 19.1 2.1 7.4 3.9 2.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_24 PF13479.6 CDJ68131.1 - 2.8 7.6 7.2 19 4.9 0.0 4.2 5 0 0 5 5 3 0 AAA domain DUF812 PF05667.11 CDJ68131.1 - 3 6.6 23.9 0.91 8.3 7.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ATG16 PF08614.11 CDJ68131.1 - 4.7 7.4 26.9 3.2 7.9 9.3 3.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Sec5 PF15469.6 CDJ68131.1 - 5.2 6.8 7.8 17 5.1 2.0 3.5 2 1 0 2 2 2 0 Exocyst complex component Sec5 ERM PF00769.19 CDJ68131.1 - 7.2 6.3 42.4 5.1 6.8 14.1 3.5 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Ribosomal_L29 PF00831.23 CDJ68132.1 - 7.6e-19 67.4 2.0 7.6e-19 67.4 2.0 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein TLD PF07534.16 CDJ68133.1 - 3.3e-20 72.7 0.0 3.7e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 TLD Cation_ATPase_N PF00690.26 CDJ68134.1 - 0.062 13.0 0.1 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus SUI1 PF01253.22 CDJ68135.1 - 8.6e-16 58.2 2.5 7.7e-15 55.2 0.1 2.2 2 0 0 2 2 2 2 Translation initiation factor SUI1 TMEM154 PF15102.6 CDJ68138.1 - 0.19 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF4713 PF15831.5 CDJ68138.1 - 0.23 11.9 0.4 0.43 11.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) RAP1 PF07218.11 CDJ68138.1 - 0.92 7.7 8.2 1.2 7.3 8.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ68138.1 - 1 9.0 15.0 2.2 7.8 15.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1180 PF06679.12 CDJ68138.1 - 1.5 9.2 10.5 4.4 7.7 10.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) PAP_central PF04928.17 CDJ68139.1 - 0.09 11.7 0.1 0.09 11.7 0.1 3.4 3 0 0 3 3 3 0 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 CDJ68139.1 - 0.24 11.7 0.0 0.49 10.7 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain Med15 PF09606.10 CDJ68140.1 - 2.8 6.5 21.3 3.7 6.1 21.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF5345 PF17280.2 CDJ68140.1 - 2.9 7.9 9.8 8.5 6.4 0.0 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5345) DUF16 PF01519.16 CDJ68140.1 - 7.8 7.0 12.3 3.4 8.2 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Ribosomal_L39 PF00832.20 CDJ68141.1 - 6.6e-23 80.1 9.8 7.3e-23 79.9 9.8 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein RCC1_2 PF13540.6 CDJ68142.1 - 0.0026 17.5 11.2 0.088 12.6 0.0 4.9 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CDJ68142.1 - 0.15 12.8 2.9 5.8 7.6 0.3 3.4 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Spt20 PF12090.8 CDJ68145.1 - 0.00019 21.1 26.9 0.011 15.4 1.4 2.1 2 0 0 2 2 2 2 Spt20 family MMR1 PF08505.10 CDJ68145.1 - 0.95 9.7 15.6 1.4 9.1 15.6 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF1980 PF09323.10 CDJ68145.1 - 1 9.2 4.8 4.6 7.1 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Hamartin PF04388.12 CDJ68145.1 - 2.7 6.6 16.2 3.4 6.2 16.2 1.0 1 0 0 1 1 1 0 Hamartin protein Cyt_bd_oxida_II PF02322.15 CDJ68145.1 - 3 7.1 9.4 0.82 9.0 2.5 2.2 2 1 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II DUF1168 PF06658.12 CDJ68146.1 - 0.0027 17.5 3.5 0.0027 17.5 3.5 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1168) DUF445 PF04286.12 CDJ68146.1 - 0.018 14.9 4.3 0.034 14.0 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) TYW3 PF02676.14 CDJ68146.1 - 0.043 13.2 2.3 0.042 13.2 0.7 1.9 2 0 0 2 2 2 0 Methyltransferase TYW3 Glyco_hydro_1 PF00232.18 CDJ68146.1 - 0.046 12.1 0.4 0.072 11.5 0.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 DUF3506 PF12014.8 CDJ68146.1 - 0.083 12.9 0.3 0.23 11.5 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) AnfO_nitrog PF09582.10 CDJ68146.1 - 0.19 11.1 4.6 0.38 10.1 4.6 1.5 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) SID-1_RNA_chan PF13965.6 CDJ68146.1 - 0.34 9.3 2.7 7.4 4.8 1.1 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF3801 PF12687.7 CDJ68146.1 - 0.48 10.5 12.0 5.6 7.0 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3801) DUF1151 PF06625.11 CDJ68146.1 - 1.1 9.2 21.3 0.25 11.3 14.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) V_ATPase_I PF01496.19 CDJ68146.1 - 1.1 7.1 14.5 0.98 7.2 0.4 2.4 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Med15 PF09606.10 CDJ68146.1 - 1.6 7.3 36.8 0.86 8.2 22.7 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal RIFIN PF02009.16 CDJ68146.1 - 1.9 8.3 11.7 4.7 7.0 5.9 2.2 2 0 0 2 2 2 0 Rifin DUF2072 PF09845.9 CDJ68146.1 - 2 8.7 6.3 0.35 11.1 1.6 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein PBP1_TM PF14812.6 CDJ68146.1 - 2.1 8.7 4.9 37 4.8 3.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CSG2 PF16965.5 CDJ68146.1 - 4.4 6.1 8.4 13 4.6 2.9 2.4 2 1 0 2 2 2 0 Ceramide synthase regulator Connexin PF00029.19 CDJ68146.1 - 6.3 6.5 7.6 0.53 10.0 1.2 2.2 2 1 0 2 2 2 0 Connexin DUF508 PF04370.12 CDJ68146.1 - 9.3 6.0 15.3 1.2 8.9 3.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF508) YebO PF13974.6 CDJ68148.1 - 0.45 10.6 5.7 1.2 9.3 1.2 2.4 2 0 0 2 2 2 0 YebO-like protein SUIM_assoc PF16619.5 CDJ68149.1 - 0.028 14.5 0.0 0.028 14.5 0.0 16.9 8 3 6 14 14 14 0 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 CDJ68150.1 - 0.008 16.2 0.1 0.008 16.2 0.1 10.2 4 3 5 9 9 9 1 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CDJ68150.1 - 9.2 6.9 18.2 16 6.2 6.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein ANAPC4_WD40 PF12894.7 CDJ68151.1 - 1.1e-05 25.6 0.0 0.03 14.6 0.0 3.6 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ68151.1 - 0.015 16.2 1.8 86 4.3 0.1 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat PUF PF00806.19 CDJ68152.1 - 7.6e-42 138.7 5.6 4.6e-06 26.0 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat TBPIP PF07106.13 CDJ68152.1 - 0.03 14.2 0.2 3.6 7.6 0.0 3.5 4 0 0 4 4 4 0 TBPIP/Hop2 winged helix domain Pkinase PF00069.25 CDJ68153.1 - 4.3e-35 121.4 0.0 2.2e-22 79.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ68153.1 - 4.8e-16 58.8 0.0 5.5e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ68153.1 - 3.8e-06 26.4 0.0 0.0026 17.1 0.1 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CDJ68153.1 - 0.00014 21.9 0.0 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ68153.1 - 0.086 11.6 0.5 0.23 10.2 0.0 1.7 1 1 1 2 2 2 0 Fungal protein kinase Sec2p PF06428.11 CDJ68153.1 - 1.3 9.1 6.0 2.9 7.9 6.0 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p SUIM_assoc PF16619.5 CDJ68154.1 - 0.0009 19.3 2.3 0.0014 18.7 2.3 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 CDJ68154.1 - 0.036 13.3 4.7 0.034 13.4 4.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3043 PF11241.8 CDJ68154.1 - 0.041 13.9 1.0 0.047 13.7 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Spt20 PF12090.8 CDJ68154.1 - 0.59 9.7 5.6 0.7 9.5 5.6 1.1 1 0 0 1 1 1 0 Spt20 family Tau95_N PF17682.1 CDJ68155.1 - 0.34 11.1 2.7 0.39 10.9 0.2 2.4 2 0 0 2 2 2 0 Tau95 Triple barrel domain DUF1980 PF09323.10 CDJ68155.1 - 7.1 6.5 8.5 1.5 8.7 1.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) T2SSM PF04612.12 CDJ68157.1 - 0.0073 16.4 3.2 0.0073 16.4 3.2 4.7 5 1 1 6 6 6 1 Type II secretion system (T2SS), protein M RskA PF10099.9 CDJ68157.1 - 0.0098 16.2 5.4 0.0098 16.2 5.4 7.7 5 1 1 6 6 6 2 Anti-sigma-K factor rskA TPR_1 PF00515.28 CDJ68158.1 - 0.00014 21.5 8.6 0.029 14.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat RskA PF10099.9 CDJ68158.1 - 0.00087 19.6 14.4 0.00087 19.6 14.4 11.3 1 1 7 8 8 8 1 Anti-sigma-K factor rskA UPF0561 PF10573.9 CDJ68159.1 - 2e-07 31.1 21.8 0.03 14.4 1.0 4.2 4 0 0 4 4 4 4 Uncharacterised protein family UPF0561 Crust_neuro_H PF03858.13 CDJ68159.1 - 1.1e-05 26.1 12.8 2.9 8.8 0.2 5.2 4 0 0 4 4 4 4 Crustacean neurohormone H Tir_receptor_N PF07490.11 CDJ68159.1 - 0.00027 20.9 14.7 0.064 13.1 1.2 3.2 3 0 0 3 3 3 3 Translocated intimin receptor (Tir) N-terminus Afaf PF15339.6 CDJ68159.1 - 0.002 17.9 4.0 5.5 6.7 0.0 3.9 4 0 0 4 4 4 2 Acrosome formation-associated factor CobS_N PF12556.8 CDJ68159.1 - 0.039 13.7 3.1 1e+02 2.7 0.0 4.2 4 0 0 4 4 4 0 Cobaltochelatase CobS subunit N terminal DUF5542 PF17696.1 CDJ68159.1 - 0.3 11.3 14.9 9.2 6.5 0.1 4.5 4 0 0 4 4 4 0 Family of unknown function (DUF5542) DUF732 PF05305.14 CDJ68159.1 - 0.39 11.1 7.9 39 4.7 0.6 3.9 1 1 2 4 4 4 0 Protein of unknown function (DUF732) SOBP PF15279.6 CDJ68159.1 - 0.46 11.0 23.1 2.5 8.6 5.5 2.2 1 1 1 2 2 2 0 Sine oculis-binding protein F420_oxidored PF03807.17 CDJ68159.1 - 2.9 8.5 7.4 1e+02 3.6 0.1 4.1 4 0 0 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent NAP PF00956.18 CDJ68159.1 - 7.4 5.7 5.7 14 4.7 2.0 2.8 1 1 1 2 2 2 0 Nucleosome assembly protein (NAP) Surface_antigen PF11054.8 CDJ68160.1 - 3.1e-34 118.7 0.8 3.5e-34 118.6 0.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Ribosomal_L27A PF00828.19 CDJ68161.1 - 0.012 16.3 0.0 0.013 16.2 0.0 1.0 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Radical_SAM PF04055.21 CDJ68162.1 - 0.23 11.8 2.2 6 7.2 0.4 2.3 2 0 0 2 2 2 0 Radical SAM superfamily Tic110 PF16940.5 CDJ68163.1 - 2.7 6.4 7.1 2.5 6.5 7.1 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter cNMP_binding PF00027.29 CDJ68164.1 - 7.4e-08 32.4 0.0 5.9e-07 29.5 0.0 2.4 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain Eryth_link_C PF16915.5 CDJ68164.1 - 0.012 15.6 0.2 0.038 14.0 0.0 1.8 2 0 0 2 2 2 0 Annelid erythrocruorin linker subunit C-terminus Ribosomal_L9_N PF01281.19 CDJ68167.1 - 3.5e-11 42.5 0.0 6.1e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DUF2722 PF10846.8 CDJ68167.1 - 0.00058 18.9 6.0 0.0023 16.9 1.4 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ68167.1 - 0.053 13.5 15.0 0.28 11.2 7.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit dsDNA_bind PF01984.20 CDJ68167.1 - 0.63 10.3 16.0 5.6 7.3 11.4 2.4 2 0 0 2 2 2 0 Double-stranded DNA-binding domain RBM39linker PF15519.6 CDJ68167.1 - 0.91 10.7 8.2 4.1 8.5 1.1 2.5 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Med3 PF11593.8 CDJ68167.1 - 2.6 7.2 21.6 0.33 10.1 10.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF4834 PF16118.5 CDJ68167.1 - 2.6 9.0 5.9 4.7 8.2 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ68167.1 - 2.8 7.5 25.4 1.2 8.7 0.5 2.1 2 0 0 2 2 2 0 Spt20 family RNA_pol_Rpc34 PF05158.12 CDJ68168.1 - 3e-36 125.5 0.5 8.3e-25 87.9 0.0 3.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit UBA_3 PF09288.10 CDJ68168.1 - 0.067 13.0 0.1 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Skp1_POZ PF03931.15 CDJ68169.1 - 1.4e-21 76.4 0.1 2.5e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 CDJ68169.1 - 2.6e-18 65.9 0.0 4.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain BTB PF00651.31 CDJ68169.1 - 0.041 14.1 0.4 1.5 9.0 0.0 2.5 2 1 0 2 2 2 0 BTB/POZ domain RskA PF10099.9 CDJ68169.1 - 0.059 13.7 10.3 0.093 13.0 10.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA acVLRF1 PF18859.1 CDJ68169.1 - 0.1 12.9 2.7 0.24 11.7 2.7 1.6 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor Rubella_E2 PF05749.11 CDJ68169.1 - 0.13 11.7 3.8 5.8 6.3 0.1 2.2 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 Acyltransferase PF01553.21 CDJ68171.1 - 7e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase PEHE PF15275.6 CDJ68172.1 - 0.0075 16.9 11.1 0.018 15.6 11.1 1.7 1 0 0 1 1 1 1 PEHE domain SLC12 PF03522.15 CDJ68172.1 - 0.5 9.3 12.6 0.69 8.9 12.6 1.4 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ68172.1 - 0.95 7.8 4.4 1.1 7.5 4.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2232 PF09991.9 CDJ68172.1 - 1.4 8.0 4.5 0.75 8.9 2.2 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) eIF-3_zeta PF05091.12 CDJ68172.1 - 3.6 6.5 18.5 5.3 5.9 18.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DnaJ PF00226.31 CDJ68173.1 - 0.0057 16.8 0.2 0.02 15.0 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain AAA PF00004.29 CDJ68174.1 - 1.8e-07 31.6 2.3 0.004 17.6 0.0 4.4 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) zf-HC5HC2H_2 PF13832.6 CDJ68175.1 - 1.8e-10 41.0 9.5 7.2e-07 29.4 0.0 3.7 4 0 0 4 4 4 2 PHD-zinc-finger like domain PHD_2 PF13831.6 CDJ68175.1 - 9e-10 38.0 1.9 9e-10 38.0 1.9 4.4 5 0 0 5 5 5 1 PHD-finger PHD PF00628.29 CDJ68175.1 - 2.4e-09 37.0 5.1 2.4e-09 37.0 5.1 3.7 4 0 0 4 4 4 1 PHD-finger zf-HC5HC2H PF13771.6 CDJ68175.1 - 3.5e-05 24.0 6.4 3.5e-05 24.0 6.4 4.6 5 0 0 5 5 5 1 PHD-like zinc-binding domain C1_1 PF00130.22 CDJ68175.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 3.9 4 0 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) IMPa_helical PF18642.1 CDJ68177.1 - 0.029 14.8 0.4 6.2 7.3 0.1 2.6 2 0 0 2 2 2 0 Immunomodulating metalloprotease helical domain DUF1180 PF06679.12 CDJ68177.1 - 4.5 7.7 7.6 14 6.1 7.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) SRP68 PF16969.5 CDJ68178.1 - 6e-42 144.4 16.4 3.5e-39 135.3 10.9 2.5 2 1 0 2 2 2 2 RNA-binding signal recognition particle 68 Ribosomal_60s PF00428.19 CDJ68178.1 - 0.018 15.6 11.9 0.018 15.6 11.9 4.9 5 0 0 5 5 5 0 60s Acidic ribosomal protein Cytochrom_C1 PF02167.15 CDJ68179.1 - 1.2e-87 293.3 0.0 2e-87 292.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CDJ68179.1 - 0.0035 17.6 0.0 0.0074 16.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CDJ68179.1 - 0.038 15.1 0.0 0.083 14.0 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c Sulfate_transp PF00916.20 CDJ68180.1 - 1.2e-21 76.9 17.3 1.4e-20 73.4 17.3 2.0 1 1 0 1 1 1 1 Sulfate permease family ATP-synt_I PF03899.15 CDJ68180.1 - 0.3 11.5 0.0 0.3 11.5 0.0 3.4 3 0 0 3 3 3 0 ATP synthase I chain Ufd2P_core PF10408.9 CDJ68181.1 - 1.2e-128 430.5 0.0 1.5e-128 430.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CDJ68181.1 - 4.6e-27 94.0 0.9 8.9e-27 93.1 0.9 1.5 1 0 0 1 1 1 1 U-box domain zf-Tim10_DDP PF02953.15 CDJ68182.1 - 1.4e-14 53.5 7.8 4.2e-14 52.0 7.8 1.7 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 CDJ68182.1 - 0.0067 16.1 4.0 0.012 15.3 4.0 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF1039 PF06287.11 CDJ68182.1 - 0.089 13.2 0.3 0.13 12.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) PIH1 PF08190.12 CDJ68183.1 - 4e-16 58.9 0.0 7.1e-13 48.4 0.0 2.4 1 1 1 2 2 2 2 PIH1 N-terminal domain DUF3123 PF11321.8 CDJ68183.1 - 0.074 13.7 0.3 0.074 13.7 0.3 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3123) DNA_pol_B PF00136.21 CDJ68190.1 - 1.5e-101 340.4 0.0 2e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_alpha_N PF12254.8 CDJ68190.1 - 8e-15 54.7 3.1 2.1e-14 53.3 3.1 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.19 CDJ68190.1 - 1.2e-13 51.0 0.0 3.9e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain BPS1 PF05633.11 CDJ68190.1 - 0.0091 15.0 2.3 1.5 7.7 2.9 2.3 2 0 0 2 2 2 2 Protein BYPASS1-related Zn-ribbon_8 PF09723.10 CDJ68190.1 - 0.45 10.7 5.9 0.59 10.3 0.9 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Macoilin PF09726.9 CDJ68190.1 - 1.6 7.2 6.2 3.9 5.9 6.2 1.6 1 0 0 1 1 1 0 Macoilin family AP2 PF00847.20 CDJ68191.1 - 4.6e-13 49.2 5.3 1.2e-12 47.8 5.3 1.7 1 0 0 1 1 1 1 AP2 domain Collagen PF01391.18 CDJ68191.1 - 8.2 6.3 8.3 0.6 9.9 3.0 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) SR-25 PF10500.9 CDJ68192.1 - 0.00059 19.5 0.3 0.00059 19.5 0.3 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein 2OG-FeII_Oxy_2 PF13532.6 CDJ68193.1 - 0.014 15.5 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily MSSP PF03940.13 CDJ68193.1 - 1.4 8.6 9.1 1e+02 2.6 9.1 2.5 1 1 0 1 1 1 0 Male specific sperm protein DUF5585 PF17823.1 CDJ68193.1 - 3.1 6.6 17.4 4.5 6.1 17.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Acyl-CoA_dh_1 PF00441.24 CDJ68195.1 - 2.9e-14 53.5 4.0 4.4e-14 53.0 4.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ68195.1 - 3e-13 49.8 0.1 5.3e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CDJ68195.1 - 7.4e-13 49.2 0.0 2.1e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CDJ68195.1 - 6.1e-08 33.0 8.1 1e-07 32.3 8.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Autophagy_C PF10381.9 CDJ68196.1 - 0.22 11.1 2.2 0.49 10.0 2.2 1.5 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Stevor PF17410.2 CDJ68196.1 - 0.56 9.7 1.8 0.67 9.5 1.8 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Peptidase_M50 PF02163.22 CDJ68196.1 - 5 6.3 16.1 3.2 7.0 1.8 3.1 1 1 1 3 3 3 0 Peptidase family M50 eRF1_1 PF03463.15 CDJ68197.1 - 3.5e-31 107.9 0.0 6.2e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 CDJ68197.1 - 1e-15 58.2 0.0 2.2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CDJ68197.1 - 4.6e-15 56.1 0.1 1.8e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 eRF1 domain 3 SUIM_assoc PF16619.5 CDJ68197.1 - 0.0029 17.6 3.2 0.0029 17.6 3.2 2.9 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 baeRF_family3 PF18845.1 CDJ68197.1 - 2.2 8.5 8.7 0.27 11.5 0.6 2.7 2 1 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 baeRF_family12 PF18856.1 CDJ68197.1 - 5.9 7.5 6.8 5.8 7.5 0.1 3.3 4 0 0 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 12 rve PF00665.26 CDJ68199.1 - 1.5e-11 44.5 0.0 2.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF5342 PF17277.2 CDJ68199.1 - 0.049 14.0 1.0 4.8 7.6 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5342) DUF2153 PF09921.9 CDJ68201.1 - 0.26 11.1 1.8 15 5.5 0.1 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) FtsJ PF01728.19 CDJ68202.1 - 6.3e-21 75.3 0.0 1.3e-18 67.8 0.0 2.5 2 0 0 2 2 2 2 FtsJ-like methyltransferase SUIM_assoc PF16619.5 CDJ68202.1 - 0.011 15.8 1.3 0.011 15.8 1.3 5.7 4 1 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 FANCAA PF15146.6 CDJ68202.1 - 0.076 12.1 0.1 0.076 12.1 0.1 1.7 2 0 0 2 2 2 0 Fanconi anemia-associated GSHPx PF00255.19 CDJ68203.1 - 4e-27 93.9 0.8 5.5e-27 93.5 0.8 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CDJ68203.1 - 2e-08 34.2 0.2 1.7e-07 31.2 0.2 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ68203.1 - 7.7e-05 22.4 0.0 0.0008 19.1 0.0 2.1 2 1 0 2 2 2 1 Redoxin Shadoo PF14999.6 CDJ68203.1 - 0.095 12.8 11.5 0.16 12.1 11.5 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.19 CDJ68203.1 - 2.1 9.0 12.0 4.5 7.9 12.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Mito_carr PF00153.27 CDJ68204.1 - 7.2e-64 211.8 3.1 2.4e-21 75.4 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_ATPase PF13246.6 CDJ68204.1 - 0.085 12.9 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Cation transport ATPase (P-type) ketoacyl-synt PF00109.26 CDJ68205.1 - 2.4e-64 217.4 0.0 5.9e-64 216.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 CDJ68205.1 - 3.3e-53 180.3 0.8 4.4e-52 176.6 0.2 3.0 4 0 0 4 4 4 1 KR domain Ketoacyl-synt_C PF02801.22 CDJ68205.1 - 3e-32 111.1 0.1 5.8e-32 110.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 CDJ68205.1 - 1e-29 103.5 0.0 1.7e-26 92.9 0.0 2.6 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 CDJ68205.1 - 1.1e-11 44.6 0.0 2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 CDJ68205.1 - 6e-11 42.5 0.9 1.4e-10 41.4 0.2 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 CDJ68205.1 - 5.9e-07 29.3 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CDJ68205.1 - 2.8e-06 27.0 0.5 0.00061 19.3 0.0 3.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ68205.1 - 0.001 18.5 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CDJ68205.1 - 0.0034 16.5 0.0 0.14 11.2 0.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Syntaxin-6_N PF09177.11 CDJ68207.1 - 1.3e-17 64.1 10.3 2.4e-16 60.1 1.6 2.3 2 0 0 2 2 2 2 Syntaxin 6, N-terminal Use1 PF09753.9 CDJ68207.1 - 0.00012 21.9 8.4 0.00021 21.1 8.4 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 CDJ68207.1 - 0.0076 16.2 1.1 0.0076 16.2 1.1 2.2 2 0 0 2 2 2 1 SNARE domain HemX PF04375.14 CDJ68207.1 - 0.1 11.9 21.3 0.33 10.2 7.3 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase TerB_N PF13208.6 CDJ68207.1 - 0.15 11.8 2.3 0.21 11.3 0.3 2.0 2 1 0 2 2 2 0 TerB N-terminal domain Spc7 PF08317.11 CDJ68207.1 - 0.17 10.7 15.5 0.29 10.0 4.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CDJ68207.1 - 0.29 9.0 5.6 0.42 8.5 5.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M61 PF05299.12 CDJ68207.1 - 0.44 10.9 2.3 0.73 10.3 0.5 2.2 1 1 1 2 2 2 0 M61 glycyl aminopeptidase Nup88 PF10168.9 CDJ68207.1 - 0.44 8.3 12.6 0.49 8.1 12.6 1.0 1 0 0 1 1 1 0 Nuclear pore component Bcr-Abl_Oligo PF09036.10 CDJ68207.1 - 1.2 9.2 8.4 2.8 8.0 0.3 3.2 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain BLOC1_2 PF10046.9 CDJ68207.1 - 1.4 9.3 11.9 0.39 11.0 0.3 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.6 CDJ68207.1 - 1.6 8.4 14.6 0.4 10.4 4.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TMPIT PF07851.13 CDJ68207.1 - 2.4 7.3 11.9 4.5 6.4 2.6 2.2 2 0 0 2 2 2 0 TMPIT-like protein MCU PF04678.13 CDJ68207.1 - 3 7.9 13.9 0.45 10.6 1.9 2.4 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Fib_alpha PF08702.10 CDJ68207.1 - 3.4 7.9 11.1 3.9 7.7 2.2 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family HAUS-augmin3 PF14932.6 CDJ68207.1 - 3.4 7.2 23.1 1.9 8.0 7.4 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Ribosomal_L23 PF00276.20 CDJ68208.1 - 6.3e-12 45.7 0.4 6.3e-12 45.7 0.4 1.9 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CDJ68208.1 - 5e-05 23.4 16.3 0.00023 21.3 16.3 2.1 1 1 0 1 1 1 1 Ribosomal protein L23, N-terminal domain TusA PF01206.17 CDJ68208.1 - 0.0045 16.8 0.1 0.0085 15.9 0.1 1.5 1 0 0 1 1 1 1 Sulfurtransferase TusA Pro_isomerase PF00160.21 CDJ68209.1 - 1.1e-40 139.5 0.0 1.2e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Coilin_N PF15862.5 CDJ68210.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 CDJ68210.1 - 0.074 11.8 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Presenilin DUF775 PF05603.12 CDJ68210.1 - 0.21 11.1 3.5 0.43 10.1 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF2722 PF10846.8 CDJ68210.1 - 1 8.3 14.6 1.5 7.6 14.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ68210.1 - 1.4 8.4 19.8 2.2 7.8 19.8 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ68210.1 - 4.8 7.1 18.2 0.49 10.3 11.0 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 CDJ68211.1 - 6.3e-07 30.0 11.6 0.0044 17.8 0.0 4.2 4 1 0 4 4 4 2 WD domain, G-beta repeat Sin_N PF04801.13 CDJ68211.1 - 0.78 8.9 18.7 0.0074 15.6 3.6 2.2 2 0 0 2 2 2 0 Sin-like protein conserved region BAF1_ABF1 PF04684.13 CDJ68211.1 - 2.5 7.0 11.3 0.81 8.7 0.9 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor SpoIIP PF07454.11 CDJ68211.1 - 5.6 6.3 9.0 0.15 11.5 0.7 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4770 PF15994.5 CDJ68211.1 - 8.6 6.6 12.5 0.45 10.7 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) WD40 PF00400.32 CDJ68212.1 - 1.8e-20 72.9 2.7 0.0022 18.8 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.8 CDJ68212.1 - 5.1e-05 22.1 0.1 0.013 14.2 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 RskA PF10099.9 CDJ68212.1 - 0.00013 22.3 19.7 0.0018 18.6 1.4 2.2 2 0 0 2 2 2 2 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ68212.1 - 0.049 14.2 3.4 0.049 14.2 3.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4834 PF16118.5 CDJ68214.1 - 0.001 20.0 7.1 0.049 14.6 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) RskA PF10099.9 CDJ68214.1 - 0.0026 18.1 0.3 0.0026 18.1 0.3 2.1 1 1 0 2 2 2 1 Anti-sigma-K factor rskA DUF4820 PF16091.5 CDJ68214.1 - 0.011 15.1 5.7 0.031 13.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) zf-C2H2_3rep PF18868.1 CDJ68214.1 - 0.032 14.9 0.2 0.032 14.9 0.2 2.1 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Presenilin PF01080.17 CDJ68214.1 - 0.059 12.1 6.9 0.069 11.9 6.9 1.1 1 0 0 1 1 1 0 Presenilin ABC2_membrane_2 PF12679.7 CDJ68214.1 - 0.21 10.8 2.9 0.28 10.4 0.1 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Spt20 PF12090.8 CDJ68214.1 - 0.3 10.7 39.9 0.31 10.6 15.1 2.1 2 0 0 2 2 2 0 Spt20 family ANAPC_CDC26 PF10471.9 CDJ68214.1 - 2 9.3 36.4 0.2 12.5 12.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF1840 PF08895.11 CDJ68214.1 - 2.6 8.4 13.7 0.36 11.2 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) RuvC_III PF18541.1 CDJ68214.1 - 3.3 7.6 12.1 0.13 12.2 2.5 2.0 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 TMEM208_SND2 PF05620.11 CDJ68214.1 - 3.8 7.3 9.9 1 9.1 0.8 2.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Pex14_N PF04695.13 CDJ68214.1 - 4.2 8.0 19.7 1.7 9.3 4.8 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AXIN1_TNKS_BD PF16646.5 CDJ68214.1 - 9.4 7.3 6.5 1.7 9.6 0.7 2.1 2 0 0 2 2 2 0 Axin-1 tankyrase binding domain SR-25 PF10500.9 CDJ68215.1 - 0.0026 17.4 10.2 0.0026 17.4 10.2 2.9 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4179 PF13786.6 CDJ68215.1 - 0.026 15.0 6.2 2.4 8.7 4.5 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) PAP2 PF01569.21 CDJ68215.1 - 0.026 14.3 0.4 14 5.4 0.7 3.3 3 0 0 3 3 3 0 PAP2 superfamily K_channel_TID PF07941.11 CDJ68215.1 - 0.041 14.3 6.0 0.041 14.3 6.0 6.8 4 2 3 7 7 7 0 Potassium channel Kv1.4 tandem inactivation domain CDC27 PF09507.10 CDJ68217.1 - 2.2 7.6 7.7 2.6 7.4 7.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf_CCCH_4 PF18345.1 CDJ68218.1 - 2.9e-09 36.6 12.4 2.2e-05 24.4 1.8 3.2 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CDJ68218.1 - 3.4e-08 33.2 8.5 8e-06 25.6 0.7 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ68218.1 - 0.015 15.1 8.4 0.024 14.4 1.7 2.9 2 0 0 2 2 2 0 CCCH-type zinc finger SUIM_assoc PF16619.5 CDJ68218.1 - 0.053 13.6 0.0 0.053 13.6 0.0 9.3 2 2 3 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 zf-C3H1 PF10650.9 CDJ68218.1 - 0.11 12.2 0.2 0.11 12.2 0.2 2.9 3 0 0 3 3 3 0 Putative zinc-finger domain adh_short PF00106.25 CDJ68220.1 - 1.9e-23 83.0 1.4 3.4e-22 78.8 1.2 2.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ68220.1 - 4.6e-17 62.4 1.5 8.5e-17 61.5 0.6 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ68220.1 - 6.2e-10 39.3 0.2 6.2e-10 39.3 0.2 1.8 2 1 0 2 2 2 1 KR domain DUF2722 PF10846.8 CDJ68220.1 - 7.6e-05 21.8 2.3 9.2e-05 21.6 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ68220.1 - 0.0027 17.8 14.6 0.0031 17.6 14.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ68220.1 - 0.0093 16.6 5.4 0.016 15.9 5.4 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CLN3 PF02487.17 CDJ68220.1 - 0.15 11.1 0.6 0.22 10.5 0.6 1.2 1 0 0 1 1 1 0 CLN3 protein TERB2 PF15101.6 CDJ68220.1 - 0.17 12.0 6.6 0.26 11.3 6.6 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PAT1 PF09770.9 CDJ68220.1 - 0.38 9.0 15.9 0.56 8.4 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RBM39linker PF15519.6 CDJ68220.1 - 0.48 11.5 8.1 1.8 9.7 6.7 2.4 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF1604 PF07713.13 CDJ68220.1 - 0.79 9.6 2.9 1.8 8.5 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) Spt20 PF12090.8 CDJ68220.1 - 5.3 6.6 25.6 8.8 5.9 25.6 1.3 1 0 0 1 1 1 0 Spt20 family ASD2 PF08687.11 CDJ68221.1 - 0.0023 17.6 12.4 0.0023 17.6 12.4 4.5 4 1 1 5 5 5 1 Apx/Shroom domain ASD2 SR-25 PF10500.9 CDJ68221.1 - 0.0024 17.5 18.9 0.0024 17.5 18.9 9.0 5 2 3 8 8 8 1 Nuclear RNA-splicing-associated protein Androgen_recep PF02166.16 CDJ68222.1 - 0.011 14.6 9.4 0.011 14.6 9.4 2.0 2 0 0 2 2 2 0 Androgen receptor CNDH2_C PF16858.5 CDJ68222.1 - 0.044 13.6 6.9 0.06 13.2 6.9 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2973 PF11189.8 CDJ68222.1 - 0.063 13.4 2.0 1.2 9.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Serinc PF03348.15 CDJ68222.1 - 0.15 11.0 2.3 0.18 10.7 2.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Senescence_reg PF04520.13 CDJ68222.1 - 0.58 11.0 7.6 0.77 10.6 7.6 1.1 1 0 0 1 1 1 0 Senescence regulator Ctr PF04145.15 CDJ68222.1 - 1.6 9.3 6.7 5.3 7.6 6.7 1.7 1 1 0 1 1 1 0 Ctr copper transporter family DUF3464 PF11947.8 CDJ68222.1 - 3.3 7.5 9.4 5.3 6.8 1.0 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4770 PF15994.5 CDJ68222.1 - 3.4 7.9 11.9 0.61 10.3 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) YqzE PF14038.6 CDJ68222.1 - 3.9 7.5 6.4 1.1 9.3 0.3 2.3 2 0 0 2 2 2 0 YqzE-like protein Coilin_N PF15862.5 CDJ68222.1 - 4.9 6.9 14.3 1 9.1 0.8 2.2 2 0 0 2 2 2 0 Coilin N-terminus DASH_Dad2 PF08654.10 CDJ68222.1 - 5.3 7.5 13.5 0.43 11.0 1.7 2.1 1 1 0 2 2 2 0 DASH complex subunit Dad2 Atg14 PF10186.9 CDJ68223.1 - 0.002 17.2 12.9 0.0024 17.0 12.9 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 GBP_C PF02841.14 CDJ68223.1 - 0.12 11.8 20.2 0.17 11.3 20.2 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain V_ATPase_I PF01496.19 CDJ68223.1 - 0.15 9.9 5.9 0.17 9.7 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cob_adeno_trans PF01923.18 CDJ68223.1 - 0.18 11.9 7.4 0.27 11.4 7.4 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3584 PF12128.8 CDJ68223.1 - 0.24 8.9 18.8 0.28 8.7 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.11 CDJ68223.1 - 0.86 8.4 13.7 0.97 8.2 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 CDJ68223.1 - 1.2 7.7 15.7 1.5 7.4 15.7 1.2 1 0 0 1 1 1 0 AAA domain SOBP PF15279.6 CDJ68223.1 - 1.8 9.1 7.9 2 8.9 7.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2151 PF10221.9 CDJ68223.1 - 2.8 6.4 7.7 3.4 6.1 7.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator AATF-Che1 PF13339.6 CDJ68223.1 - 3.2 8.4 14.0 6.2 7.5 14.0 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Spt20 PF12090.8 CDJ68223.1 - 3.9 7.0 10.2 5 6.7 10.2 1.3 1 0 0 1 1 1 0 Spt20 family AAA_23 PF13476.6 CDJ68223.1 - 4.1 7.8 8.3 6.1 7.3 8.3 1.3 1 0 0 1 1 1 0 AAA domain FemAB PF02388.16 CDJ68223.1 - 5 5.9 14.2 6.5 5.5 14.2 1.2 1 0 0 1 1 1 0 FemAB family DUF572 PF04502.13 CDJ68223.1 - 5.1 6.6 13.3 5.8 6.4 13.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Presenilin PF01080.17 CDJ68223.1 - 6.7 5.4 9.6 6.8 5.3 9.6 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ68223.1 - 7.6 3.5 13.6 8.9 3.3 13.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SKA1 PF07160.12 CDJ68223.1 - 8.1 6.2 14.1 1.5 8.6 9.5 1.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Dynamitin PF04912.14 CDJ68223.1 - 9.4 5.4 19.5 15 4.8 19.5 1.3 1 1 0 1 1 1 0 Dynamitin MAD PF05557.13 CDJ68223.1 - 9.5 4.4 16.8 12 4.1 16.8 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Golgin_A5 PF09787.9 CDJ68223.1 - 9.6 5.6 14.8 11 5.3 14.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4460 PF14687.6 CDJ68224.1 - 0.0042 17.1 0.0 0.0042 17.1 0.0 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4460) Folate_carrier PF01770.18 CDJ68224.1 - 0.12 11.1 1.0 0.22 10.2 1.0 1.4 1 0 0 1 1 1 0 Reduced folate carrier GxGYxYP_C PF14323.6 CDJ68224.1 - 0.13 12.1 1.4 0.24 11.3 1.4 1.4 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain CLN3 PF02487.17 CDJ68224.1 - 3.1 6.7 4.9 7.6 5.5 4.9 1.6 1 0 0 1 1 1 0 CLN3 protein TFIIA PF03153.13 CDJ68224.1 - 4.3 7.2 49.5 55 3.6 49.5 2.2 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Het-C PF07217.11 CDJ68224.1 - 8.2 4.8 12.3 0.46 9.0 7.1 1.6 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C LMBR1 PF04791.16 CDJ68224.1 - 8.7 5.1 9.9 3.2 6.6 7.1 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein MMR_HSR1_Xtn PF16897.5 CDJ68225.1 - 1.6e-40 137.4 0.1 2.8e-40 136.6 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CDJ68225.1 - 3.7e-22 78.1 0.0 7.7e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CDJ68225.1 - 3.3e-21 75.5 0.0 6.3e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ68225.1 - 1.4e-11 44.2 0.1 7.6e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ68225.1 - 0.00017 21.7 0.1 0.48 10.5 0.2 2.5 1 1 0 2 2 2 2 Dynamin family MeaB PF03308.16 CDJ68225.1 - 0.00035 19.6 0.2 0.0025 16.8 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 CDJ68225.1 - 0.04 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_6 PF12774.7 CDJ68227.1 - 3.4e-09 36.1 0.1 6e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ68227.1 - 1.4e-08 34.3 0.1 2.4e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 DHC_N2 PF08393.13 CDJ68228.1 - 5.3e-23 81.8 0.0 1.1e-22 80.7 0.0 1.4 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 HisKA_3 PF07730.13 CDJ68228.1 - 0.0039 17.7 2.1 0.11 13.1 0.0 3.5 2 2 2 4 4 4 1 Histidine kinase ABC_tran_CTD PF16326.5 CDJ68228.1 - 0.015 15.5 2.5 0.015 15.5 2.5 3.1 4 0 0 4 4 4 0 ABC transporter C-terminal domain PilJ PF13675.6 CDJ68228.1 - 0.045 13.8 1.2 0.48 10.5 0.0 2.8 2 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term GntR PF00392.21 CDJ68228.1 - 0.062 13.0 0.6 7.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Alkyl_sulf_C PF14864.6 CDJ68228.1 - 0.1 12.9 0.2 0.97 9.7 0.0 2.4 3 0 0 3 3 3 0 Alkyl sulfatase C-terminal Baculo_PEP_C PF04513.12 CDJ68228.1 - 0.13 12.3 6.8 0.1 12.6 0.3 2.8 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2722 PF10846.8 CDJ68229.1 - 0.0054 15.7 3.2 0.0054 15.7 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ68229.1 - 0.007 16.0 6.6 0.0076 15.9 6.6 1.1 1 0 0 1 1 1 1 Spt20 family DUF4834 PF16118.5 CDJ68229.1 - 0.0077 17.2 0.8 0.0092 16.9 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ68229.1 - 0.028 14.4 6.4 0.03 14.3 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPIS-gp6 PF16722.5 CDJ68229.1 - 0.081 13.3 5.2 0.16 12.4 5.2 1.5 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus Glyco_hydro_9 PF00759.19 CDJ68229.1 - 0.12 11.7 2.7 0.13 11.7 2.7 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 DUF5421 PF17458.2 CDJ68229.1 - 0.2 11.0 7.7 0.28 10.5 7.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) EMC3_TMCO1 PF01956.16 CDJ68229.1 - 0.34 10.6 1.4 0.44 10.2 1.4 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like BRF1 PF07741.13 CDJ68229.1 - 0.45 10.9 4.6 0.54 10.6 4.6 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF2514 PF10721.9 CDJ68229.1 - 0.54 10.3 15.4 0.74 9.8 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Roughex PF06020.11 CDJ68229.1 - 0.68 9.0 4.4 0.72 8.9 4.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein FTZ PF03867.14 CDJ68229.1 - 1.2 8.6 4.5 1.5 8.3 4.5 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region DUF3138 PF11336.8 CDJ68229.1 - 3 6.4 11.9 3.3 6.2 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Lant_dehydr_C PF14028.6 CDJ68232.1 - 0.01 15.4 1.4 0.011 15.4 1.4 1.0 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term DUF3509 PF12021.8 CDJ68232.1 - 0.025 14.3 3.2 0.042 13.6 1.7 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3509) CENP-K PF11802.8 CDJ68232.1 - 0.069 12.7 7.4 0.084 12.4 7.4 1.0 1 0 0 1 1 1 0 Centromere-associated protein K CNDH2_M PF16869.5 CDJ68232.1 - 0.1 13.3 1.4 0.2 12.4 1.3 1.5 1 1 0 1 1 1 0 PF16858 KAsynt_C_assoc PF16197.5 CDJ68232.1 - 0.18 12.3 1.2 0.23 11.9 1.2 1.3 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Elongin_A PF06881.11 CDJ68232.1 - 1.1 9.8 7.1 0.27 11.8 1.7 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CRF PF00473.17 CDJ68232.1 - 1.5 8.9 6.4 4.9 7.3 0.2 2.4 2 0 0 2 2 2 0 Corticotropin-releasing factor family DUF1043 PF06295.12 CDJ68232.1 - 1.7 8.7 10.7 13 5.8 10.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Ras PF00071.22 CDJ68233.1 - 1e-60 204.0 0.0 1.2e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ68233.1 - 1.1e-35 122.5 0.0 1.4e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ68233.1 - 2.5e-13 49.9 0.0 3.1e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ68233.1 - 3.6e-06 27.0 0.0 5.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ68233.1 - 0.00028 20.8 0.3 0.048 13.6 0.1 2.1 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CDJ68233.1 - 0.00033 20.2 0.0 0.00063 19.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDJ68233.1 - 0.00071 19.0 0.0 0.00093 18.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 CDJ68233.1 - 0.0018 18.0 0.1 0.0027 17.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ68233.1 - 0.011 16.1 0.0 0.017 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CDJ68233.1 - 0.012 15.9 0.0 0.04 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CDJ68233.1 - 0.052 13.6 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 CDJ68233.1 - 0.056 12.8 0.0 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein SRPRB PF09439.10 CDJ68233.1 - 0.079 12.4 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 CDJ68233.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CDJ68233.1 - 0.18 11.3 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SR-25 PF10500.9 CDJ68236.1 - 0.0019 17.9 3.2 0.0019 17.9 3.2 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SARAF PF06682.12 CDJ68236.1 - 0.014 15.1 1.4 0.014 15.1 1.4 1.6 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis TFIIA PF03153.13 CDJ68236.1 - 0.22 11.5 24.0 0.15 12.0 10.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1685 PF07939.11 CDJ68236.1 - 0.28 10.9 3.2 0.43 10.4 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1685) UQ_con PF00179.26 CDJ68237.1 - 9.4e-29 99.9 0.0 1.4e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CDJ68237.1 - 0.076 12.9 0.7 0.85 9.5 0.7 2.0 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 CDJ68237.1 - 0.12 12.6 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain ACDC PF14733.6 CDJ68238.1 - 5.8e-08 32.9 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 AP2-coincident C-terminal MMS1_N PF10433.9 CDJ68239.1 - 6.1e-99 331.9 0.0 1.2e-98 331.0 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CDJ68239.1 - 1.7e-79 267.5 0.0 2.9e-79 266.7 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region DUF3704 PF12488.8 CDJ68239.1 - 0.2 11.4 0.4 0.48 10.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Peptidase_S24 PF00717.23 CDJ68240.1 - 1.8e-06 27.8 0.0 2.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like IML1 PF12257.8 CDJ68241.1 - 0.2 10.7 0.0 0.43 9.7 0.0 1.4 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 APG5 PF04106.12 CDJ68241.1 - 0.4 10.2 2.4 1.1 8.8 2.4 1.7 1 0 0 1 1 1 0 Autophagy protein Apg5 Hep_59 PF07052.11 CDJ68241.1 - 4.2 8.2 6.4 28 5.5 0.1 3.3 3 0 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 DDE_Tnp_ISL3 PF01610.17 CDJ68241.1 - 7.9 6.1 7.0 0.65 9.7 1.7 1.9 2 0 0 2 2 2 0 Transposase CS PF04969.16 CDJ68242.1 - 4.3e-15 56.5 0.0 8.4e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 CDJ68242.1 - 7.6e-12 45.0 0.2 1.5e-11 44.1 0.2 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. FGF-BP1 PF06473.12 CDJ68242.1 - 0.4 10.5 0.0 0.4 10.5 0.0 3.0 2 2 1 3 3 3 0 FGF binding protein 1 (FGF-BP1) SLC12 PF03522.15 CDJ68242.1 - 2.4 7.1 11.7 0.48 9.4 6.6 1.9 2 0 0 2 2 2 0 Solute carrier family 12 DUF3987 PF13148.6 CDJ68242.1 - 5.3 5.9 9.2 9.5 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PikAIV_N PF18605.1 CDJ68243.1 - 0.00074 19.0 16.9 0.027 14.1 4.9 3.9 3 0 0 3 3 3 2 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Leu_zip PF15294.6 CDJ68243.1 - 0.14 11.7 27.3 0.03 13.8 13.0 3.5 2 1 2 4 4 4 0 Leucine zipper Myb_DNA-binding PF00249.31 CDJ68244.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain SWM_repeat PF13753.6 CDJ68244.1 - 0.17 12.1 0.3 0.74 10.0 0.3 2.1 2 0 0 2 2 2 0 Putative flagellar system-associated repeat EF-hand_1 PF00036.32 CDJ68245.1 - 9.2e-21 71.8 0.6 7.9e-07 28.2 0.2 3.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CDJ68245.1 - 1.4e-19 70.3 0.4 2.7e-12 47.0 0.2 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ68245.1 - 1.6e-18 65.0 0.3 1.9e-06 27.4 0.0 3.5 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CDJ68245.1 - 1.8e-12 46.9 0.5 3.7e-06 26.7 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CDJ68245.1 - 4.2e-12 45.0 0.6 1e-05 24.8 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_11 PF08976.11 CDJ68245.1 - 1.3e-05 26.0 0.0 1.7e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 CDJ68245.1 - 0.00029 20.7 0.1 0.91 9.5 0.0 2.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CDJ68245.1 - 0.0007 19.9 0.1 0.01 16.2 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CDJ68245.1 - 0.0016 18.7 0.0 0.0046 17.3 0.0 1.7 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CDJ68245.1 - 0.0032 17.4 0.0 0.091 12.7 0.0 2.3 1 1 0 1 1 1 1 Caleosin related protein DUF1547 PF07577.11 CDJ68245.1 - 0.026 14.9 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) Dockerin_1 PF00404.18 CDJ68245.1 - 0.041 14.1 0.1 0.36 11.1 0.0 2.4 2 1 0 2 2 2 0 Dockerin type I domain DUF5580 PF17743.1 CDJ68245.1 - 0.065 11.8 0.0 0.077 11.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) MHCassoc_trimer PF08831.10 CDJ68245.1 - 0.16 12.0 0.3 9.4 6.3 0.1 2.3 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Myb_DNA-binding PF00249.31 CDJ68248.1 - 1.8e-10 40.9 0.2 3.7e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ68248.1 - 2.6e-06 27.6 1.5 3.4e-06 27.2 0.2 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Fasciclin PF02469.22 CDJ68249.1 - 9.2e-07 29.1 0.0 2.4e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain Raf1_HTH PF18579.1 CDJ68250.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Notch PF00066.17 CDJ68252.1 - 1.9e-40 137.0 108.4 1.3e-07 31.9 4.7 7.0 6 1 1 7 7 7 7 LNR domain DUF4949 PF16307.5 CDJ68252.1 - 0.0037 17.4 0.2 0.0068 16.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4949) Mog1 PF04603.12 CDJ68253.1 - 3.9e-29 101.8 0.0 5e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein ANAPC15 PF15243.6 CDJ68254.1 - 0.23 11.9 6.9 0.32 11.4 6.9 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 ubiquitin PF00240.23 CDJ68255.1 - 2.7e-13 49.4 0.1 2.2e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CDJ68255.1 - 0.0009 19.0 0.2 0.0023 17.7 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDJ68255.1 - 0.0028 17.6 2.5 0.086 12.9 0.3 3.0 2 2 0 2 2 2 1 Ubiquitin-like domain IMCp PF12314.8 CDJ68256.1 - 6.2e-26 90.5 51.5 8.6e-25 86.9 21.5 3.5 1 1 2 3 3 3 3 Inner membrane complex protein VPS11_C PF12451.8 CDJ68257.1 - 1.3e-05 25.3 0.1 4e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 CDJ68257.1 - 0.0032 17.3 0.3 0.011 15.6 0.1 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS PHD PF00628.29 CDJ68257.1 - 0.0059 16.5 0.3 0.021 14.7 0.3 2.0 1 0 0 1 1 1 1 PHD-finger zf-C3H2C3 PF17122.5 CDJ68257.1 - 0.015 15.3 4.2 0.015 15.3 4.2 2.1 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4_2 PF13923.6 CDJ68257.1 - 0.016 15.1 1.4 0.016 15.1 1.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ68257.1 - 0.035 14.0 2.3 0.17 11.8 2.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ68257.1 - 0.065 13.2 3.0 0.24 11.4 3.0 2.1 1 0 0 1 1 1 0 zinc-RING finger domain zf-TFIIIC PF12660.7 CDJ68257.1 - 0.27 11.2 2.1 1.8 8.6 0.6 2.7 2 1 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex zf-RING_2 PF13639.6 CDJ68257.1 - 0.87 10.0 7.1 9.9 6.6 7.3 2.7 1 1 1 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 CDJ68257.1 - 0.88 9.7 3.9 0.39 10.8 0.8 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 CDJ68257.1 - 2.5 8.4 10.9 0.66 10.3 1.2 3.6 3 0 0 3 3 3 0 RING-H2 zinc finger domain Asp_protease_2 PF13650.6 CDJ68258.1 - 0.038 14.6 0.0 0.092 13.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 CDJ68258.1 - 0.11 12.6 6.1 0.45 10.7 0.2 3.3 3 0 0 3 3 3 0 Zinc knuckle gag-asp_proteas PF13975.6 CDJ68258.1 - 0.13 12.9 0.0 0.35 11.4 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 CDJ68259.1 - 6.5e-10 38.9 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L24e PF01246.20 CDJ68260.1 - 1.1e-23 83.2 0.7 1.1e-23 83.2 0.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 CDJ68260.1 - 0.086 12.4 0.2 0.097 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) APO_RNA-bind PF05634.11 CDJ68260.1 - 0.25 10.7 5.7 0.35 10.2 5.7 1.3 1 0 0 1 1 1 0 APO RNA-binding BolA PF01722.18 CDJ68261.1 - 0.046 14.0 0.0 0.083 13.2 0.0 1.4 1 0 0 1 1 1 0 BolA-like protein Trigger_C PF05698.14 CDJ68262.1 - 1.5e-15 57.6 9.7 4.7e-15 56.0 9.7 1.8 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus Trigger_N PF05697.13 CDJ68262.1 - 0.01 16.2 0.4 0.18 12.1 0.0 2.6 3 0 0 3 3 3 0 Bacterial trigger factor protein (TF) N6_N4_Mtase PF01555.18 CDJ68263.1 - 0.016 14.9 0.1 0.039 13.7 0.1 1.6 1 0 0 1 1 1 0 DNA methylase UPF0020 PF01170.18 CDJ68263.1 - 0.063 12.9 0.0 0.16 11.6 0.0 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Pam16 PF03656.13 CDJ68264.1 - 2.1e-11 43.9 0.0 2.5e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Pam16 Prenyltrans PF00432.21 CDJ68266.1 - 9.5e-35 118.0 23.4 5.6e-12 45.2 1.0 5.5 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Actin PF00022.19 CDJ68267.1 - 1.9e-75 254.0 0.0 3.4e-68 230.1 0.0 2.2 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.13 CDJ68267.1 - 0.0055 15.6 0.0 0.083 11.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein SMC_N PF02463.19 CDJ68268.1 - 1.1e-08 34.7 0.1 1.1e-08 34.7 0.1 2.5 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ68268.1 - 9.6e-07 29.5 0.0 9.6e-07 29.5 0.0 4.4 2 1 1 3 3 3 1 AAA domain Glyco_transf_34 PF05637.12 CDJ68268.1 - 2.1 8.0 6.4 0.24 11.1 1.4 2.0 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family Chorion_S16 PF05836.12 CDJ68268.1 - 7.6 6.8 8.4 56 4.0 4.0 2.9 2 0 0 2 2 2 0 Chorion protein S16 SMC_N PF02463.19 CDJ68269.1 - 9.2e-15 54.7 0.2 1.1e-14 54.4 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ68269.1 - 3.4e-08 33.7 0.1 4e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CDJ68269.1 - 2.5e-06 27.6 0.3 7.2e-06 26.2 0.2 1.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CDJ68269.1 - 3e-05 23.9 0.0 3.6e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 CDJ68269.1 - 0.0012 19.3 1.0 0.0038 17.7 0.1 2.1 2 1 0 2 2 2 1 ABC transporter tRNA-synt_2d PF01409.20 CDJ68270.1 - 1.7e-18 67.0 0.0 2.8e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Peptidase_M16 PF00675.20 CDJ68270.1 - 2.1e-18 66.7 0.1 2.1e-18 66.7 0.1 6.8 8 0 0 8 8 8 1 Insulinase (Peptidase family M16) FDX-ACB PF03147.14 CDJ68270.1 - 9.6e-17 61.2 0.0 9.6e-17 61.2 0.0 3.6 4 0 0 4 4 4 1 Ferredoxin-fold anticodon binding domain TFIIA PF03153.13 CDJ68270.1 - 7.9e-05 22.8 59.2 0.00013 22.1 24.1 12.3 7 3 4 12 12 12 2 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ68270.1 - 0.00075 18.6 2.9 0.00075 18.6 2.9 14.2 13 2 1 14 14 14 2 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ68270.1 - 0.0008 19.1 3.4 0.0008 19.1 3.4 16.5 12 4 3 16 16 16 3 Nuclear RNA-splicing-associated protein Peptidase_M16_C PF05193.21 CDJ68270.1 - 0.063 13.3 20.0 0.088 12.8 0.0 5.4 6 0 0 6 6 6 0 Peptidase M16 inactive domain DUF2690 PF10901.8 CDJ68271.1 - 0.012 15.9 2.2 0.013 15.8 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2690) Spt20 PF12090.8 CDJ68271.1 - 0.03 13.9 28.2 0.027 14.1 28.2 1.1 1 0 0 1 1 1 0 Spt20 family DUF853 PF05872.12 CDJ68271.1 - 0.082 11.5 6.2 0.09 11.3 6.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AIF_C PF14721.6 CDJ68271.1 - 0.11 12.9 4.2 0.12 12.8 4.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Connexin PF00029.19 CDJ68271.1 - 0.23 11.2 4.5 0.23 11.2 4.5 1.0 1 0 0 1 1 1 0 Connexin Rpp20 PF12328.8 CDJ68271.1 - 0.3 11.1 5.9 0.35 10.8 5.9 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Androgen_recep PF02166.16 CDJ68271.1 - 0.42 9.4 27.2 0.46 9.3 27.2 1.0 1 0 0 1 1 1 0 Androgen receptor EIIBC-GUT_N PF03612.14 CDJ68271.1 - 0.51 10.1 6.7 0.49 10.1 6.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peroxin-13_N PF04088.13 CDJ68271.1 - 0.73 10.1 5.3 0.8 10.0 5.3 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region TFIIA PF03153.13 CDJ68271.1 - 0.83 9.6 25.8 0.75 9.7 25.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ68271.1 - 0.92 8.9 9.2 0.85 9.0 9.2 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ68271.1 - 0.96 8.3 16.1 0.89 8.5 16.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex14_N PF04695.13 CDJ68271.1 - 1 10.0 13.9 1.1 9.9 13.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ68271.1 - 1.1 9.2 12.9 1 9.3 12.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Orf78 PF06024.12 CDJ68271.1 - 1.2 9.5 3.5 1.4 9.3 3.5 1.1 1 0 0 1 1 1 0 Orf78 (ac78) Ctr PF04145.15 CDJ68271.1 - 1.3 9.7 5.2 1.3 9.6 5.2 1.0 1 0 0 1 1 1 0 Ctr copper transporter family DUF4407 PF14362.6 CDJ68271.1 - 1.4 8.2 11.2 1.3 8.3 11.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4834 PF16118.5 CDJ68271.1 - 1.6 9.7 12.4 1.8 9.6 12.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CSG2 PF16965.5 CDJ68271.1 - 1.8 7.4 3.4 1.8 7.4 3.4 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Presenilin PF01080.17 CDJ68271.1 - 2.3 6.9 10.1 2 7.1 10.1 1.0 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ68271.1 - 4.2 7.4 5.7 4.2 7.4 5.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ68271.1 - 4.4 6.3 5.8 4.1 6.3 5.8 1.0 1 0 0 1 1 1 0 CLN3 protein DUF3464 PF11947.8 CDJ68271.1 - 5.1 6.8 9.6 5.7 6.7 9.6 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2722 PF10846.8 CDJ68271.1 - 6.7 5.5 29.1 6.8 5.5 29.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ68272.1 - 0.00048 19.8 1.8 0.00048 19.8 1.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.8 CDJ68272.1 - 6 5.7 23.9 2.3 7.1 14.0 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Androgen_recep PF02166.16 CDJ68272.1 - 8.1 5.2 21.0 0.89 8.3 11.5 2.2 2 0 0 2 2 2 0 Androgen receptor SUIM_assoc PF16619.5 CDJ68273.1 - 0.0041 17.1 7.1 0.0041 17.1 7.1 4.5 3 2 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 DUF3824 PF12868.7 CDJ68273.1 - 0.15 12.7 0.2 0.15 12.7 0.2 6.5 5 3 1 6 6 6 0 Domain of unknwon function (DUF3824) DUF4834 PF16118.5 CDJ68273.1 - 1.3 10.0 32.8 3.8 8.5 7.5 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) DUF1645 PF07816.11 CDJ68274.1 - 0.00074 20.2 0.7 0.00074 20.2 0.7 11.8 9 3 1 10 10 10 2 Protein of unknown function (DUF1645) RskA PF10099.9 CDJ68274.1 - 0.008 16.5 0.0 0.008 16.5 0.0 18.3 5 4 7 13 13 13 2 Anti-sigma-K factor rskA Herpes_glycop PF01528.16 CDJ68274.1 - 0.036 12.9 0.8 0.075 11.9 0.8 1.5 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Pam17 PF08566.10 CDJ68274.1 - 0.038 13.8 0.1 0.21 11.4 0.1 2.3 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 DER1 PF04511.15 CDJ68276.1 - 5.2e-12 46.1 0.0 4.3e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Der1-like family Cas_Csy4 PF09618.10 CDJ68276.1 - 0.029 14.5 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) PPP4R2 PF09184.11 CDJ68278.1 - 0.056 13.0 23.0 0.064 12.8 23.0 1.2 1 0 0 1 1 1 0 PPP4R2 DUF4045 PF13254.6 CDJ68278.1 - 0.11 12.2 36.0 0.12 12.0 36.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Raftlin PF15250.6 CDJ68278.1 - 4 6.1 40.3 5.1 5.7 40.3 1.1 1 0 0 1 1 1 0 Raftlin Dsh_C PF12316.8 CDJ68278.1 - 4 7.8 26.1 7.4 6.9 26.1 1.5 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Actin PF00022.19 CDJ68279.1 - 5.2e-06 25.3 0.0 0.13 10.9 0.0 3.3 3 0 0 3 3 3 2 Actin X8 PF07983.13 CDJ68279.1 - 0.00033 21.3 0.8 0.053 14.2 0.4 2.9 1 1 1 2 2 2 2 X8 domain TFIIA PF03153.13 CDJ68279.1 - 0.069 13.1 3.6 0.11 12.5 3.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ETRAMP PF09716.10 CDJ68279.1 - 0.2 11.7 1.4 0.79 9.8 1.5 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) SUZ PF12752.7 CDJ68279.1 - 3.5 8.5 5.9 65 4.4 3.2 2.6 2 0 0 2 2 2 0 SUZ domain Spt20 PF12090.8 CDJ68280.1 - 0.00017 21.3 8.2 0.00017 21.3 8.2 7.0 5 1 1 6 6 6 3 Spt20 family DUF2722 PF10846.8 CDJ68280.1 - 0.0017 17.4 7.2 0.0017 17.4 7.2 8.8 6 4 0 6 6 6 2 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ68282.1 - 0.011 16.0 15.6 0.011 16.0 15.6 3.0 1 1 2 3 3 3 0 Anti-sigma-K factor rskA EutN_CcmL PF03319.13 CDJ68282.1 - 0.12 12.9 0.5 0.38 11.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutN/carboxysome Activator_LAG-3 PF11498.8 CDJ68282.1 - 1.7 7.6 71.2 0.048 12.6 42.0 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 O-antigen_lig PF13425.6 CDJ68282.1 - 2.4 6.8 3.1 3.1 6.5 3.1 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4813 PF16072.5 CDJ68283.1 - 1.5 8.4 33.5 1.8 8.2 33.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) ANAPC4_WD40 PF12894.7 CDJ68284.1 - 6.2e-13 48.9 0.0 5.4e-06 26.6 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ68284.1 - 9.8e-12 45.2 2.6 0.02 15.7 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat RskA PF10099.9 CDJ68284.1 - 0.085 13.2 0.1 0.085 13.2 0.1 8.3 3 3 2 5 5 5 0 Anti-sigma-K factor rskA Ge1_WD40 PF16529.5 CDJ68284.1 - 0.088 11.8 0.0 13 4.7 0.0 2.6 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyoxal_oxid_N PF07250.11 CDJ68284.1 - 0.11 11.7 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus BBS2_Mid PF14783.6 CDJ68284.1 - 0.23 11.5 0.0 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DDHD PF02862.17 CDJ68284.1 - 2.6 8.1 12.7 5.3 7.1 3.1 3.3 3 0 0 3 3 3 0 DDHD domain TFIIA PF03153.13 CDJ68285.1 - 0.19 11.7 23.8 0.23 11.4 23.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GAGA_bind PF06217.12 CDJ68285.1 - 2.6 8.3 10.4 3.4 7.9 10.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Spc7 PF08317.11 CDJ68285.1 - 3 6.6 35.4 4.1 6.2 35.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GREB1 PF15782.5 CDJ68285.1 - 3.7 4.5 12.0 4.2 4.4 12.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LMBR1 PF04791.16 CDJ68285.1 - 8.7 5.1 5.3 9.1 5.1 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 CDJ68285.1 - 8.7 4.1 13.9 11 3.8 13.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Brr6_like_C_C PF10104.9 CDJ68286.1 - 1.2e-21 76.8 0.0 3.9e-21 75.2 0.0 1.9 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain ANAPC_CDC26 PF10471.9 CDJ68286.1 - 0.011 16.5 3.3 0.011 16.5 3.3 5.8 5 0 0 5 5 5 0 Anaphase-promoting complex APC subunit CDC26 DUF1645 PF07816.11 CDJ68286.1 - 0.014 16.0 0.9 0.014 16.0 0.9 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1645) OATP PF03137.20 CDJ68286.1 - 0.041 12.2 0.1 0.041 12.2 0.1 2.5 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4834 PF16118.5 CDJ68286.1 - 0.098 13.6 22.6 0.34 11.9 0.4 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 CDJ68286.1 - 5.7 6.9 16.0 0.021 14.9 1.3 2.5 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Renin_r PF07850.14 CDJ68286.1 - 7.4 7.2 6.4 27 5.4 0.0 3.4 3 0 0 3 3 3 0 Renin receptor-like protein Sua5_yciO_yrdC PF01300.18 CDJ68287.1 - 1e-13 51.2 0.0 4.5e-11 42.6 0.0 2.9 2 0 0 2 2 2 2 Telomere recombination SUA5 PF03481.13 CDJ68287.1 - 3.3e-10 40.7 1.7 3.3e-10 40.7 1.7 2.9 2 1 1 3 3 3 1 Putative GTP-binding controlling metal-binding SR-25 PF10500.9 CDJ68287.1 - 0.00012 21.8 6.9 0.00012 21.8 6.9 5.6 5 2 0 6 6 6 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ68287.1 - 0.00083 19.0 12.4 0.0024 17.5 1.5 2.5 2 0 0 2 2 2 2 Spt20 family Peptidase_S64 PF08192.11 CDJ68287.1 - 0.31 9.5 9.2 0.025 13.1 1.5 2.2 2 0 0 2 2 2 0 Peptidase family S64 F-box-like PF12937.7 CDJ68288.1 - 4.4e-06 26.5 0.2 9.5e-06 25.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDJ68288.1 - 0.0045 16.8 2.1 0.023 14.5 0.0 2.6 2 0 0 2 2 2 1 F-box domain Exonuc_VII_L PF02601.15 CDJ68288.1 - 1.1 8.8 18.7 2.4 7.7 18.7 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2151 PF10221.9 CDJ68288.1 - 9.2 4.7 14.3 14 4.1 14.3 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Cofilin_ADF PF00241.20 CDJ68290.1 - 0.055 13.3 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Ribosomal_S9 PF00380.19 CDJ68291.1 - 1.2e-34 119.4 0.2 1.2e-34 119.4 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S9/S16 SLATT_1 PF18181.1 CDJ68291.1 - 0.013 15.4 1.4 0.026 14.4 1.4 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 RPN2_C PF18004.1 CDJ68291.1 - 0.017 15.0 0.2 0.026 14.4 0.2 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain UPF0560 PF10577.9 CDJ68291.1 - 3.1 6.2 9.3 4.7 5.6 9.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIA PF03153.13 CDJ68292.1 - 0.2 11.6 46.7 0.25 11.3 46.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ68292.1 - 1.2 9.4 20.5 2.3 8.5 19.4 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Peptidase_S64 PF08192.11 CDJ68292.1 - 3.4 6.0 39.8 3.9 5.9 39.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 SOBP PF15279.6 CDJ68292.1 - 7.6 7.1 37.2 10 6.6 37.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein RVT_1 PF00078.27 CDJ68293.1 - 0.00028 20.5 0.0 0.00058 19.4 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_MCEL PF03291.16 CDJ68294.1 - 5.5e-16 58.6 0.0 2.3e-09 36.8 0.0 2.4 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.12 CDJ68294.1 - 0.00017 22.3 0.1 0.00052 20.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ68294.1 - 0.00036 21.2 0.0 0.0011 19.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ68294.1 - 0.00079 20.0 0.0 0.0022 18.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ68294.1 - 0.013 15.2 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF5567 PF17722.1 CDJ68294.1 - 0.034 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5567) GHMP_kinases_C PF08544.13 CDJ68294.1 - 0.1 13.0 0.1 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 GHMP kinases C terminal SR-25 PF10500.9 CDJ68294.1 - 4.8 6.7 13.5 8.7 5.9 13.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4578 PF15147.6 CDJ68294.1 - 7.4 7.5 8.5 0.89 10.4 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4578) SPG4 PF17325.2 CDJ68295.1 - 0.18 12.9 0.6 0.18 12.9 0.6 4.4 2 1 2 4 4 4 0 Stationary phase protein 4 TFIIA PF03153.13 CDJ68296.1 - 0.29 11.1 7.9 0.48 10.4 7.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit T_Ag_DNA_bind PF02217.16 CDJ68297.1 - 0.0062 17.1 0.3 0.016 15.8 0.3 1.8 1 0 0 1 1 1 1 Origin of replication binding protein DUF1269 PF06897.12 CDJ68297.1 - 0.11 12.8 3.1 4.6 7.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) CBM_15 PF03426.14 CDJ68297.1 - 0.13 11.8 6.3 0.25 10.9 6.3 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) DUF1645 PF07816.11 CDJ68297.1 - 0.3 11.6 6.8 1 9.9 4.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) DUF4667 PF15700.5 CDJ68297.1 - 1.7 8.6 12.1 1.3 9.0 7.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Ligase_CoA PF00549.19 CDJ68297.1 - 3.3 7.5 10.4 5.7 6.8 2.6 2.9 3 0 0 3 3 3 0 CoA-ligase Filament_head PF04732.14 CDJ68298.1 - 0.4 11.6 34.8 0.96 10.4 10.9 3.8 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region Pep1_7 PF17232.2 CDJ68298.1 - 0.92 10.0 18.0 13 6.3 1.7 4.5 4 0 0 4 4 4 0 Elicitor peptide 1-7 SUZ PF12752.7 CDJ68298.1 - 9.2 7.1 15.9 3 8.7 1.0 4.0 3 0 0 3 3 3 0 SUZ domain UPF0160 PF03690.13 CDJ68299.1 - 6.4e-40 137.7 0.0 7.7e-21 75.0 0.0 2.9 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0160) RAB3GAP2_N PF14655.6 CDJ68299.1 - 0.25 10.5 4.4 0.45 9.7 4.1 1.5 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIA PF03153.13 CDJ68299.1 - 0.96 9.4 16.8 0.36 10.8 14.6 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ68299.1 - 1.3 8.6 16.6 1.9 8.0 16.6 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ68300.1 - 0.0049 16.9 30.3 0.0061 16.6 30.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ68300.1 - 0.028 14.1 52.3 0.13 11.8 13.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2232 PF09991.9 CDJ68300.1 - 1 8.5 5.1 1.4 8.1 4.0 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) Peptidase_C37 PF05416.12 CDJ68300.1 - 1.1 7.7 9.2 1.3 7.4 9.2 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF4401 PF14351.6 CDJ68300.1 - 1.5 8.1 14.8 2.2 7.5 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF5585 PF17823.1 CDJ68300.1 - 1.6 7.6 38.1 2.3 7.1 38.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) DUF5327 PF17261.2 CDJ68300.1 - 2.8 8.7 14.2 11 6.8 7.9 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Spt20 PF12090.8 CDJ68300.1 - 3 7.4 25.3 2.3 7.8 19.7 2.1 2 0 0 2 2 2 0 Spt20 family SID-1_RNA_chan PF13965.6 CDJ68300.1 - 3.5 5.9 5.7 0.89 7.9 2.4 1.5 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 FemAB PF02388.16 CDJ68300.1 - 5.3 5.8 8.3 0.52 9.1 3.9 1.5 2 0 0 2 2 2 0 FemAB family SEEEED PF14797.6 CDJ68300.1 - 5.4 7.2 36.6 4.2 7.5 7.5 2.1 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex RskA PF10099.9 CDJ68300.1 - 5.8 7.2 51.3 0.055 13.8 25.0 2.6 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Ubiquitin_2 PF14560.6 CDJ68301.1 - 5.6e-08 33.1 0.0 1.6e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain DUF4746 PF15928.5 CDJ68301.1 - 1.3e-05 24.8 11.4 2.9e-05 23.7 11.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4746) CAP_GLY PF01302.25 CDJ68301.1 - 8e-05 22.6 0.3 0.024 14.7 0.1 2.3 2 0 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.7 CDJ68301.1 - 8.1e-05 22.9 10.9 5 7.7 0.2 6.1 5 1 2 7 7 7 1 Leucine Rich repeats (2 copies) DUF2722 PF10846.8 CDJ68301.1 - 0.00037 19.6 11.6 0.00037 19.6 11.6 4.3 3 1 1 4 4 2 1 Protein of unknown function (DUF2722) LRR_8 PF13855.6 CDJ68301.1 - 0.0013 18.4 6.9 1.4 8.8 0.0 4.7 4 1 1 5 5 5 1 Leucine rich repeat SDA1 PF05285.12 CDJ68301.1 - 0.0018 17.7 16.9 0.0045 16.5 16.9 1.6 1 0 0 1 1 1 1 SDA1 Hid1 PF12722.7 CDJ68301.1 - 0.0029 15.8 19.6 0.0045 15.2 19.6 1.3 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein TFIIA PF03153.13 CDJ68301.1 - 0.0041 17.2 91.1 0.071 13.1 17.7 4.3 4 0 0 4 4 4 3 Transcription factor IIA, alpha/beta subunit DUF2052 PF09747.9 CDJ68301.1 - 0.086 13.0 31.5 0.1 12.7 21.0 2.7 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) XRN_M PF17846.1 CDJ68301.1 - 0.11 11.4 14.1 0.054 12.4 7.9 2.2 2 0 0 2 2 2 0 Xrn1 helical domain AAA_11 PF13086.6 CDJ68301.1 - 0.14 11.9 24.4 0.094 12.5 15.6 2.3 2 0 0 2 2 2 0 AAA domain CSG2 PF16965.5 CDJ68301.1 - 0.82 8.5 11.2 0.46 9.4 5.7 2.3 2 0 0 2 2 2 0 Ceramide synthase regulator DUF2151 PF10221.9 CDJ68301.1 - 1 7.8 13.3 1.6 7.2 13.3 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator LRR_1 PF00560.33 CDJ68301.1 - 1.4 9.7 11.0 48 5.1 0.0 5.4 5 0 0 5 5 4 0 Leucine Rich Repeat DUF2828 PF11443.8 CDJ68301.1 - 1.7 6.6 27.5 0.63 8.1 19.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) V_ATPase_I PF01496.19 CDJ68301.1 - 2 6.3 33.2 0.6 8.0 23.3 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Band_3_cyto PF07565.13 CDJ68301.1 - 2.4 7.9 28.9 1.6 8.5 1.6 2.8 3 0 0 3 3 3 0 Band 3 cytoplasmic domain SID-1_RNA_chan PF13965.6 CDJ68301.1 - 2.8 6.3 11.0 0.36 9.2 5.2 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 ALMT PF11744.8 CDJ68301.1 - 3.1 6.5 22.7 0.9 8.3 14.5 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter Connexin PF00029.19 CDJ68301.1 - 5.6 6.7 23.7 5.6 6.7 0.3 2.7 2 0 0 2 2 2 0 Connexin BORG_CEP PF14957.6 CDJ68301.1 - 6.3 8.0 29.6 3 9.0 13.2 4.5 5 0 0 5 5 5 0 Cdc42 effector O-antigen_lig PF13425.6 CDJ68301.1 - 6.4 5.4 11.2 5.9 5.6 7.3 2.0 2 0 0 2 2 2 0 O-antigen ligase like membrane protein PA26 PF04636.13 CDJ68301.1 - 7.1 5.4 21.6 0.44 9.4 11.0 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) MAJIN PF15077.6 CDJ68301.1 - 7.7 6.2 22.1 0.35 10.6 10.0 2.4 2 0 0 2 2 2 0 Membrane-anchored junction protein Tim54 PF11711.8 CDJ68301.1 - 8.9 5.0 32.0 0.44 9.3 17.0 2.8 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 ATP-synt_E PF05680.12 CDJ68302.1 - 0.49 10.8 13.2 2.8 8.3 2.8 2.5 2 0 0 2 2 2 0 ATP synthase E chain DUF1614 PF07758.11 CDJ68302.1 - 0.76 9.8 4.0 0.15 12.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) Presenilin PF01080.17 CDJ68302.1 - 1.6 7.4 9.5 2.2 6.9 9.5 1.2 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 CDJ68302.1 - 2.3 8.2 17.9 4 7.4 8.0 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 HABP4_PAI-RBP1 PF04774.15 CDJ68302.1 - 8.8 7.2 10.4 1.2 10.0 2.7 2.4 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family DUF755 PF05501.11 CDJ68303.1 - 8e-05 22.9 21.8 8e-05 22.9 21.8 14.4 12 3 3 15 15 15 4 Domain of unknown function (DUF755) TFIIA PF03153.13 CDJ68303.1 - 0.0022 18.1 47.8 0.0022 18.1 47.8 6.8 3 1 3 6 6 6 3 Transcription factor IIA, alpha/beta subunit DsbD_2 PF13386.6 CDJ68303.1 - 0.19 11.7 2.5 1.2 9.1 0.1 3.0 3 0 0 3 3 3 0 Cytochrome C biogenesis protein transmembrane region DNA_pol_phi PF04931.13 CDJ68304.1 - 1.3e-07 30.2 5.7 1.4e-07 30.0 5.7 1.0 1 0 0 1 1 1 1 DNA polymerase phi SUIM_assoc PF16619.5 CDJ68304.1 - 0.0075 16.3 1.6 0.014 15.5 1.6 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CDJ68304.1 - 0.06 13.9 13.7 0.2 12.2 13.7 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein TMEM171 PF15471.6 CDJ68304.1 - 0.63 9.0 4.7 0.52 9.2 3.5 1.4 1 1 0 1 1 1 0 Transmembrane protein family 171 Rotamase_2 PF13145.6 CDJ68304.1 - 2.2 9.1 7.5 7.3 7.5 7.5 2.0 1 1 0 1 1 1 0 PPIC-type PPIASE domain NDUF_B7 PF05676.13 CDJ68305.1 - 0.034 13.9 6.7 0.94 9.2 0.7 2.4 1 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 CDJ68305.1 - 0.49 10.6 7.3 3.6 7.8 0.2 3.1 2 1 1 3 3 3 0 CHCH domain SLR1-BP PF07333.12 CDJ68305.1 - 3.2 8.3 7.7 0.72 10.3 3.2 2.0 1 1 1 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) CX9C PF16860.5 CDJ68305.1 - 5.5 7.1 11.8 1.3 9.0 3.4 2.4 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, SUIM_assoc PF16619.5 CDJ68306.1 - 0.011 15.8 8.4 0.011 15.8 8.4 3.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3742 PF12553.8 CDJ68306.1 - 0.061 13.5 0.6 0.44 10.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) Spt20 PF12090.8 CDJ68306.1 - 0.64 9.6 31.0 0.039 13.6 13.2 2.3 2 0 0 2 2 2 0 Spt20 family 5_nucleotid PF05761.14 CDJ68306.1 - 2.4 6.9 5.3 5.2 5.9 5.3 1.5 1 0 0 1 1 1 0 5' nucleotidase family DUF4834 PF16118.5 CDJ68306.1 - 8.8 7.4 20.9 0.053 14.5 5.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) stn_TNFRSF12A PF12191.8 CDJ68307.1 - 0.044 14.0 0.4 0.044 14.0 0.4 1.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Crust_neuro_H PF03858.13 CDJ68307.1 - 0.047 14.5 0.2 0.11 13.3 0.2 1.7 1 0 0 1 1 1 0 Crustacean neurohormone H XRN_N PF03159.18 CDJ68308.1 - 1.7e-66 224.1 0.0 2.7e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CDJ68308.1 - 1.5e-49 169.2 16.8 1e-22 80.8 0.0 3.8 4 0 0 4 4 4 3 Xrn1 helical domain Glutaredoxin PF00462.24 CDJ68309.1 - 0.013 15.8 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin zf-IS66 PF13005.7 CDJ68309.1 - 0.089 13.2 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 DUF4637 PF15470.6 CDJ68310.1 - 0.0048 16.6 1.3 0.011 15.5 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) YicC_N PF03755.13 CDJ68310.1 - 0.062 13.8 0.3 0.062 13.8 0.3 1.6 2 0 0 2 2 2 0 YicC-like family, N-terminal region EF-hand_1 PF00036.32 CDJ68314.1 - 4.1e-15 54.1 0.0 0.008 15.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ68314.1 - 6.7e-15 55.3 0.0 4.9e-06 26.9 0.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ68314.1 - 1.5e-13 49.5 0.0 0.002 17.9 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_9 PF14658.6 CDJ68314.1 - 2.8e-08 34.0 0.0 0.00056 20.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ68314.1 - 2.9e-08 32.8 0.1 0.15 11.6 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CDJ68314.1 - 9.7e-08 31.7 0.2 0.12 12.3 0.0 3.9 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ68314.1 - 0.16 12.3 0.0 21 5.5 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region VIT1 PF01988.19 CDJ68315.1 - 2.3e-47 161.6 0.5 3.4e-47 161.1 0.5 1.3 1 0 0 1 1 1 1 VIT family SNF PF00209.18 CDJ68316.1 - 1.5e-18 66.8 32.4 1.5e-18 66.8 32.4 2.1 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family DUF1298 PF06974.13 CDJ68318.1 - 0.00072 19.5 0.1 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 CDJ68318.1 - 0.33 10.7 3.2 0.31 10.8 0.1 2.6 3 1 0 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Glutaredoxin PF00462.24 CDJ68319.1 - 0.0023 18.1 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Ku PF02735.16 CDJ68320.1 - 1.1e-20 74.3 0.0 2.4e-20 73.1 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 CDJ68320.1 - 3e-17 62.9 0.1 5.1e-10 39.5 0.0 2.9 2 1 0 2 2 2 2 Ku C terminal domain like 7TMR-HDED PF07697.11 CDJ68320.1 - 1.9 8.6 12.5 0.77 9.8 8.3 2.2 2 0 0 2 2 2 0 7TM-HD extracellular Ku_C PF03730.14 CDJ68320.1 - 3 8.6 5.9 0.32 11.7 0.2 2.3 2 1 1 3 3 3 0 Ku70/Ku80 C-terminal arm TAXi_N PF14543.6 CDJ68321.1 - 5.6e-11 43.0 0.8 5.6e-11 43.0 0.8 3.2 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp PF00026.23 CDJ68321.1 - 2.5e-08 33.7 0.0 0.00047 19.7 0.0 3.9 4 0 0 4 4 4 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 CDJ68321.1 - 5e-06 26.4 0.0 0.014 15.2 0.0 3.9 4 0 0 4 4 4 2 Xylanase inhibitor C-terminal SPX PF03105.19 CDJ68321.1 - 9.8 6.0 11.0 6 6.7 4.9 2.4 2 0 0 2 2 2 0 SPX domain RRM_Rrp7 PF17799.1 CDJ68322.1 - 0.026 14.3 0.0 0.026 14.3 0.0 2.8 3 1 0 3 3 3 0 Rrp7 RRM-like N-terminal domain TrbC PF04956.13 CDJ68322.1 - 4.3 7.6 7.4 0.63 10.3 0.3 2.8 2 0 0 2 2 2 0 TrbC/VIRB2 family RRM_1 PF00076.22 CDJ68323.1 - 2.7e-08 33.5 0.0 0.3 10.9 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S9 PF00326.21 CDJ68324.1 - 2.4e-13 50.0 4.9 4.4e-05 23.1 0.3 3.8 2 1 1 3 3 3 3 Prolyl oligopeptidase family Spt20 PF12090.8 CDJ68325.1 - 0.002 17.8 32.0 0.056 13.1 4.5 3.2 3 0 0 3 3 3 3 Spt20 family RskA PF10099.9 CDJ68325.1 - 0.0055 17.0 72.2 0.0086 16.4 1.1 5.4 4 1 0 5 5 5 3 Anti-sigma-K factor rskA IMUP PF15761.5 CDJ68325.1 - 0.027 15.1 12.6 0.027 15.1 12.6 3.5 4 0 0 4 4 4 0 Immortalisation up-regulated protein CCDC24 PF15669.5 CDJ68325.1 - 0.95 9.3 17.9 2.1 8.2 9.9 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 24 family DUF4667 PF15700.5 CDJ68325.1 - 1.5 8.8 17.1 0.08 13.0 9.7 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) RAP1 PF07218.11 CDJ68325.1 - 7.9 4.6 4.8 12 4.1 4.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Utp14 PF04615.13 CDJ68326.1 - 3.6 6.0 39.5 4.4 5.8 39.5 1.1 1 0 0 1 1 1 0 Utp14 protein DCP2 PF05026.13 CDJ68327.1 - 1.9e-14 53.8 0.9 1.9e-14 53.8 0.9 1.8 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 CDJ68327.1 - 3e-12 46.7 0.0 8.6e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain SR-25 PF10500.9 CDJ68328.1 - 0.00025 20.8 12.8 0.00025 20.8 12.8 5.4 5 2 0 5 5 5 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ68328.1 - 0.72 9.4 63.6 0.17 11.5 22.9 4.3 4 0 0 4 4 4 0 Spt20 family Pyridox_ox_2 PF12900.7 CDJ68329.1 - 0.02 14.9 0.4 0.02 14.9 0.4 2.4 3 0 0 3 3 3 0 Pyridoxamine 5'-phosphate oxidase RLL PF10036.9 CDJ68329.1 - 0.9 9.3 10.8 0.019 14.8 2.9 2.1 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein DinB PF05163.12 CDJ68329.1 - 3.7 7.4 8.7 1.6 8.7 4.2 2.4 1 1 1 2 2 2 0 DinB family Spt20 PF12090.8 CDJ68329.1 - 6.7 6.3 8.7 15 5.1 8.7 1.6 1 0 0 1 1 1 0 Spt20 family ABC_tran PF00005.27 CDJ68330.1 - 6.8e-33 114.1 0.1 1.3e-16 61.4 0.0 3.2 4 0 0 4 4 2 2 ABC transporter AAA_29 PF13555.6 CDJ68330.1 - 4.2e-09 36.0 0.1 0.0034 17.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_membrane PF00664.23 CDJ68330.1 - 2.5e-07 30.6 1.0 2.5e-07 30.6 1.0 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region MMR_HSR1 PF01926.23 CDJ68330.1 - 4.1e-07 30.1 0.1 0.0046 17.0 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF2722 PF10846.8 CDJ68330.1 - 6.4e-06 25.4 12.2 0.0058 15.6 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) AAA_22 PF13401.6 CDJ68330.1 - 1.9e-05 24.9 7.6 0.02 15.2 0.0 4.5 5 0 0 5 5 5 2 AAA domain AAA_21 PF13304.6 CDJ68330.1 - 1.9e-05 24.6 3.2 0.016 15.0 0.1 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CDJ68330.1 - 3.5e-05 24.4 0.1 0.06 13.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain SUIM_assoc PF16619.5 CDJ68330.1 - 0.00012 22.1 0.0 0.00012 22.1 0.0 4.0 2 2 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 AAA_19 PF13245.6 CDJ68330.1 - 0.00015 22.1 1.2 0.00089 19.6 0.1 2.8 2 1 0 2 2 1 1 AAA domain Spt20 PF12090.8 CDJ68330.1 - 0.00018 21.2 26.4 0.0044 16.7 3.3 2.5 2 0 0 2 2 2 2 Spt20 family NTPase_1 PF03266.15 CDJ68330.1 - 0.0002 21.3 0.1 0.05 13.5 0.0 2.6 2 0 0 2 2 2 1 NTPase Ribosomal_60s PF00428.19 CDJ68330.1 - 0.00029 21.3 5.1 0.00029 21.3 5.1 9.8 8 1 1 9 9 7 1 60s Acidic ribosomal protein AAA_7 PF12775.7 CDJ68330.1 - 0.00031 20.3 0.1 0.052 13.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 CDJ68330.1 - 0.00032 19.9 0.2 0.3 10.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein ATPase_2 PF01637.18 CDJ68330.1 - 0.00043 20.3 0.1 0.081 12.8 0.0 3.0 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea cobW PF02492.19 CDJ68330.1 - 0.0005 19.7 1.0 0.12 11.9 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA12 PF10443.9 CDJ68330.1 - 0.0014 17.4 0.0 0.0014 17.4 0.0 2.2 3 0 0 3 3 2 1 RNA12 protein SMC_N PF02463.19 CDJ68330.1 - 0.0017 17.8 0.0 0.75 9.2 0.0 2.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 CDJ68330.1 - 0.0017 17.8 0.2 2.3 7.6 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 CDJ68330.1 - 0.0017 18.1 0.3 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 CDJ68330.1 - 0.0017 18.3 4.2 0.34 10.8 0.0 3.1 3 0 0 3 3 3 2 NACHT domain AAA_16 PF13191.6 CDJ68330.1 - 0.0021 18.5 7.5 0.0021 18.5 7.5 5.2 3 2 1 4 4 3 2 AAA ATPase domain MeaB PF03308.16 CDJ68330.1 - 0.0026 16.8 7.2 0.14 11.1 0.1 2.8 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 CDJ68330.1 - 0.0031 16.8 0.9 0.19 11.0 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 CDJ68330.1 - 0.0031 17.4 5.7 0.62 10.0 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase ATP_bind_1 PF03029.17 CDJ68330.1 - 0.005 16.6 0.1 0.98 9.2 0.0 2.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 CDJ68330.1 - 0.0056 16.1 0.2 0.89 8.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF815 PF05673.13 CDJ68330.1 - 0.0059 15.8 0.2 0.19 10.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.6 CDJ68330.1 - 0.0064 17.0 0.1 0.035 14.6 0.1 4.8 5 1 0 5 5 3 2 AAA domain TsaE PF02367.17 CDJ68330.1 - 0.0086 16.1 0.1 1.5 8.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CDJ68330.1 - 0.017 14.9 0.2 4.5 6.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CDJ68330.1 - 0.02 14.5 0.7 2.7 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CDJ68330.1 - 0.021 15.2 0.9 1.6 9.1 0.0 2.8 3 0 0 3 3 2 0 RNA helicase PsbH PF00737.20 CDJ68330.1 - 0.022 14.5 0.2 0.051 13.3 0.2 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein AAA_5 PF07728.14 CDJ68330.1 - 0.031 14.3 4.5 0.32 11.0 0.1 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CDJ68330.1 - 0.037 14.1 0.1 8 6.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 CDJ68330.1 - 0.039 14.0 0.5 0.4 10.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 CDJ68330.1 - 0.041 14.0 12.4 0.087 13.0 0.0 4.4 5 0 0 5 5 4 0 AAA domain AAA_11 PF13086.6 CDJ68330.1 - 0.042 13.6 0.0 0.042 13.6 0.0 3.9 4 1 0 4 4 2 0 AAA domain AAA PF00004.29 CDJ68330.1 - 0.057 13.8 0.1 0.057 13.8 0.1 3.8 5 0 0 5 5 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CDJ68330.1 - 0.072 12.8 0.1 12 5.6 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein EPL1 PF10513.9 CDJ68330.1 - 0.077 13.4 2.0 4.7 7.6 0.4 2.7 2 0 0 2 2 2 0 Enhancer of polycomb-like RAB3GAP2_N PF14655.6 CDJ68330.1 - 0.32 10.2 6.5 4.1 6.5 1.1 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus NB-ARC PF00931.22 CDJ68330.1 - 0.73 9.0 7.2 4.4 6.4 0.1 2.8 3 0 0 3 3 2 0 NB-ARC domain TFIIA PF03153.13 CDJ68330.1 - 2.7 7.9 41.7 0.076 13.0 8.0 3.6 3 1 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ68330.1 - 4.9 6.0 9.1 3.5 6.5 2.5 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2075 PF09848.9 CDJ68330.1 - 6.1 6.0 11.6 0.48 9.6 0.1 3.6 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) Adeno_IVa2 PF02456.15 CDJ68330.1 - 7.1 5.3 7.0 2.6 6.7 0.1 2.5 3 0 0 3 3 2 0 Adenovirus IVa2 protein Med15 PF09606.10 CDJ68330.1 - 8.6 4.9 32.4 0.25 10.0 5.0 2.8 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA PF00004.29 CDJ68331.1 - 1.6e-33 115.9 0.0 4.1e-33 114.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CDJ68331.1 - 6.9e-09 35.5 0.1 1.4e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CDJ68331.1 - 2.1e-07 31.5 0.1 0.00011 22.6 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 CDJ68331.1 - 5.1e-07 30.0 0.0 4.9e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CDJ68331.1 - 5.8e-06 26.1 0.0 1.9e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ68331.1 - 1.5e-05 25.0 0.1 0.00033 20.7 0.1 2.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CDJ68331.1 - 0.00045 20.0 0.1 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDJ68331.1 - 0.0005 20.4 0.4 0.019 15.2 0.0 2.8 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CDJ68331.1 - 0.00071 19.4 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CDJ68331.1 - 0.00076 19.0 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 CDJ68331.1 - 0.0013 18.0 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 CDJ68331.1 - 0.0014 18.4 0.0 0.0051 16.5 0.0 2.0 2 1 0 2 2 1 1 Sigma-54 interaction domain RNA_helicase PF00910.22 CDJ68331.1 - 0.0019 18.6 0.0 0.0041 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 CDJ68331.1 - 0.0023 18.5 0.0 0.023 15.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDJ68331.1 - 0.0029 17.0 0.1 0.0059 16.0 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 CDJ68331.1 - 0.0044 16.6 0.0 0.0099 15.5 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 CDJ68331.1 - 0.005 16.8 0.1 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CDJ68331.1 - 0.0064 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 CDJ68331.1 - 0.0066 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CDJ68331.1 - 0.0089 16.2 0.0 0.036 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CDJ68331.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CDJ68331.1 - 0.012 15.1 0.1 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 CDJ68331.1 - 0.015 15.6 0.1 0.052 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CDJ68331.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 CDJ68331.1 - 0.031 13.6 0.0 0.072 12.4 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 CDJ68331.1 - 0.034 13.9 1.9 0.14 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CDJ68331.1 - 0.035 13.7 0.4 0.089 12.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CDJ68331.1 - 0.091 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 CDJ68331.1 - 0.11 13.1 0.3 0.69 10.4 0.0 2.3 2 2 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.6 CDJ68331.1 - 0.11 12.6 0.0 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain UMP1 PF05348.11 CDJ68332.1 - 4.2e-12 46.3 0.0 4.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 CAP_N PF01213.19 CDJ68332.1 - 0.29 10.6 0.9 0.37 10.2 0.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Unstab_antitox PF09720.10 CDJ68333.1 - 0.036 14.1 0.1 0.1 12.7 0.1 1.8 1 0 0 1 1 1 0 Putative addiction module component Aldedh PF00171.22 CDJ68333.1 - 0.43 9.0 19.4 0.044 12.3 0.1 3.4 4 1 0 4 4 4 0 Aldehyde dehydrogenase family Glyco_hydro_9 PF00759.19 CDJ68333.1 - 1.4 8.3 9.5 2.2 7.6 4.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 Shadoo PF14999.6 CDJ68333.1 - 4.9 7.2 23.1 1.7 8.7 13.5 2.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Hexapep PF00132.24 CDJ68335.1 - 4.2e-06 26.3 2.5 3.2e-05 23.5 0.2 2.1 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) RskA PF10099.9 CDJ68335.1 - 1.5e-05 25.4 7.3 2e-05 25.0 7.3 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ68335.1 - 0.00096 19.3 6.3 0.00097 19.2 6.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit EphA2_TM PF14575.6 CDJ68335.1 - 0.047 14.6 0.4 1.8 9.5 1.5 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Glyco_tranf_2_5 PF13712.6 CDJ68335.1 - 0.086 12.5 1.3 0.16 11.6 1.3 1.4 1 1 0 1 1 1 0 Glycosyltransferase like family Hexapep_2 PF14602.6 CDJ68335.1 - 0.13 12.0 0.5 0.13 12.0 0.5 1.7 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF4834 PF16118.5 CDJ68335.1 - 1.5 9.8 6.9 2.2 9.3 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Ribosomal_60s PF00428.19 CDJ68335.1 - 4.2 8.0 12.0 8 7.1 12.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF755 PF05501.11 CDJ68336.1 - 0.018 15.3 11.5 0.018 15.3 11.5 6.5 5 1 0 5 5 5 0 Domain of unknown function (DUF755) Filament_head PF04732.14 CDJ68336.1 - 6.7 7.7 49.4 7.6 7.5 2.3 3.5 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region TFIIA PF03153.13 CDJ68337.1 - 1.7e-05 25.0 69.1 0.0009 19.4 16.3 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Otopetrin PF03189.13 CDJ68337.1 - 0.00053 18.9 9.2 0.00085 18.3 9.2 1.2 1 0 0 1 1 1 1 Otopetrin SPX PF03105.19 CDJ68337.1 - 0.0019 18.2 18.5 0.0092 15.9 5.6 2.3 2 0 0 2 2 2 2 SPX domain DDHD PF02862.17 CDJ68337.1 - 0.0038 17.4 0.2 0.0038 17.4 0.2 2.4 2 1 0 2 2 2 1 DDHD domain PIP5K PF01504.18 CDJ68337.1 - 0.0043 16.3 13.1 0.023 13.9 4.3 2.2 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Presenilin PF01080.17 CDJ68337.1 - 0.0076 15.1 30.1 0.016 14.0 13.0 2.2 2 0 0 2 2 2 2 Presenilin SID-1_RNA_chan PF13965.6 CDJ68337.1 - 0.011 14.2 3.5 0.099 11.0 0.5 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Velvet PF11754.8 CDJ68337.1 - 0.017 15.1 28.6 0.04 13.9 15.2 2.3 2 0 0 2 2 2 0 Velvet factor MRP-S31 PF15433.6 CDJ68337.1 - 0.02 14.6 20.3 0.17 11.5 7.7 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 UPF0564 PF10595.9 CDJ68337.1 - 0.021 13.9 33.3 0.052 12.6 15.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 RR_TM4-6 PF06459.12 CDJ68337.1 - 0.025 14.4 27.3 0.022 14.6 11.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RPOL_N PF14700.6 CDJ68337.1 - 0.032 13.6 24.9 0.015 14.7 9.2 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal Neur_chan_memb PF02932.16 CDJ68337.1 - 0.033 14.3 19.3 0.014 15.4 6.9 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 CDJ68337.1 - 0.061 12.8 25.2 0.23 10.9 12.2 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4471 PF14740.6 CDJ68337.1 - 0.087 12.0 9.3 0.11 11.7 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Adaptin_binding PF10199.9 CDJ68337.1 - 0.097 13.3 16.3 0.12 12.9 2.5 2.6 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 EPL1 PF10513.9 CDJ68337.1 - 0.1 13.0 27.2 1.4 9.3 3.0 3.1 3 0 0 3 3 3 0 Enhancer of polycomb-like CCSAP PF15748.5 CDJ68337.1 - 0.13 12.4 41.4 0.44 10.7 22.7 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SOBP PF15279.6 CDJ68337.1 - 0.14 12.7 29.9 0.13 12.9 17.5 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein AAR2 PF05282.11 CDJ68337.1 - 0.18 11.2 12.5 0.22 10.9 1.5 2.2 2 0 0 2 2 2 0 AAR2 protein SLC12 PF03522.15 CDJ68337.1 - 0.21 10.6 25.4 0.088 11.8 9.8 2.1 2 0 0 2 2 2 0 Solute carrier family 12 eIF-3_zeta PF05091.12 CDJ68337.1 - 0.23 10.4 30.4 0.014 14.4 11.4 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Apt1 PF10351.9 CDJ68337.1 - 0.24 10.2 13.3 0.06 12.2 2.7 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF702 PF05142.12 CDJ68337.1 - 0.58 10.6 32.5 5.2 7.5 12.8 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF702) Hamartin PF04388.12 CDJ68337.1 - 0.98 8.0 32.4 1.7 7.2 18.6 2.0 2 0 0 2 2 2 0 Hamartin protein DUF5523 PF17661.1 CDJ68337.1 - 1.4 8.6 24.7 0.6 9.8 10.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DUF1980 PF09323.10 CDJ68337.1 - 1.6 8.7 17.2 0.45 10.4 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF913 PF06025.12 CDJ68337.1 - 1.6 7.6 17.5 1 8.3 6.4 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 CDJ68337.1 - 2.4 7.9 25.4 0.53 10.0 11.3 2.2 2 0 0 2 2 2 0 Connexin SR-25 PF10500.9 CDJ68337.1 - 2.5 7.7 36.4 2.1 7.9 24.4 2.6 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Endostatin PF06482.11 CDJ68337.1 - 2.5 7.5 30.9 0.71 9.3 15.6 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Peroxin-3 PF04882.12 CDJ68337.1 - 2.8 6.9 32.3 0.076 12.0 10.7 2.2 2 0 0 2 2 2 0 Peroxin-3 Scs3p PF10261.9 CDJ68337.1 - 2.8 7.4 8.4 1.8 8.0 0.5 2.5 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM PAT1 PF09770.9 CDJ68337.1 - 3 6.0 58.9 0.91 7.7 16.0 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 VIR_N PF15912.5 CDJ68337.1 - 3.2 7.3 19.7 0.51 9.9 10.4 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal Serinc PF03348.15 CDJ68337.1 - 4.9 6.0 16.3 0.29 10.0 4.1 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF2052 PF09747.9 CDJ68337.1 - 9.1 6.4 28.9 3.9 7.6 11.6 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) GPCR_chapero_1 PF11904.8 CDJ68337.1 - 9.8 5.5 16.3 1.6 8.1 4.4 2.7 3 0 0 3 3 3 0 GPCR-chaperone TAF6_C PF07571.13 CDJ68338.1 - 1.6e-07 31.6 0.3 6.9e-07 29.5 0.3 2.1 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TFIIA PF03153.13 CDJ68338.1 - 0.002 18.2 7.9 0.002 18.2 7.9 4.1 3 1 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ68338.1 - 0.0079 15.2 2.8 0.0079 15.2 2.8 4.5 3 2 1 4 4 4 2 Protein of unknown function (DUF2722) TAF PF02969.17 CDJ68338.1 - 0.055 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Spt20 PF12090.8 CDJ68339.1 - 0.0082 15.8 15.2 0.0098 15.5 15.2 1.0 1 0 0 1 1 1 1 Spt20 family CTU2 PF10288.9 CDJ68339.1 - 0.015 15.5 4.8 0.017 15.4 4.8 1.1 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF1178 PF06676.11 CDJ68339.1 - 0.029 14.8 7.6 0.033 14.6 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) FYDLN_acid PF09538.10 CDJ68339.1 - 0.32 11.7 4.4 0.41 11.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) EIIBC-GUT_N PF03612.14 CDJ68339.1 - 0.37 10.5 3.8 0.45 10.2 3.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4820 PF16091.5 CDJ68339.1 - 0.39 10.1 7.3 0.47 9.8 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF2722 PF10846.8 CDJ68339.1 - 0.41 9.5 18.2 0.51 9.2 18.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Androgen_recep PF02166.16 CDJ68339.1 - 1.5 7.6 11.7 1.3 7.7 11.7 1.2 1 0 0 1 1 1 0 Androgen receptor Med3 PF11593.8 CDJ68339.1 - 1.8 7.6 12.0 2.1 7.5 12.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-RanBP PF00641.18 CDJ68339.1 - 1.9 7.9 5.2 2.9 7.3 5.2 1.2 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF4834 PF16118.5 CDJ68339.1 - 2.3 9.2 7.9 2.9 8.9 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ68339.1 - 3.6 6.2 6.9 4.1 6.1 6.9 1.0 1 0 0 1 1 1 0 Presenilin SARAF PF06682.12 CDJ68340.1 - 0.0029 17.3 7.6 0.0029 17.3 7.6 2.6 2 1 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4179 PF13786.6 CDJ68340.1 - 0.93 10.0 0.0 0.93 10.0 0.0 5.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4179) DUF572 PF04502.13 CDJ68340.1 - 5.9 6.4 37.1 1.8 8.1 21.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) RNA_pol_Rpc4 PF05132.14 CDJ68341.1 - 0.14 12.6 19.2 0.16 12.4 19.2 1.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 Peptidase_U57 PF05582.12 CDJ68341.1 - 0.47 9.7 17.7 0.51 9.5 17.7 1.0 1 0 0 1 1 1 0 YabG peptidase U57 PIP5K PF01504.18 CDJ68341.1 - 1.4 8.1 19.7 1.3 8.2 19.7 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase AIF_C PF14721.6 CDJ68341.1 - 1.7 9.0 17.2 2 8.8 17.2 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Afi1 PF07792.12 CDJ68341.1 - 1.7 9.1 21.0 1.7 9.1 21.0 1.0 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF5308 PF17233.2 CDJ68341.1 - 1.9 8.7 19.1 2.1 8.6 19.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Gti1_Pac2 PF09729.9 CDJ68341.1 - 2.5 8.2 19.8 2.7 8.0 19.8 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family CPSF100_C PF13299.6 CDJ68341.1 - 3.7 7.7 20.2 4.4 7.5 20.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FYDLN_acid PF09538.10 CDJ68341.1 - 3.8 8.2 12.6 5.6 7.7 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1764 PF08576.10 CDJ68341.1 - 3.9 8.4 20.6 5 8.1 20.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) FAM176 PF14851.6 CDJ68341.1 - 4.9 6.8 14.8 5.9 6.5 14.8 1.1 1 0 0 1 1 1 0 FAM176 family SpoIIP PF07454.11 CDJ68341.1 - 5 6.5 27.2 5.4 6.4 27.2 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 CDJ68341.1 - 5.1 5.8 22.0 5.7 5.6 22.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MMU163 PF17119.5 CDJ68341.1 - 5.2 6.2 12.0 5.7 6.0 12.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis RR_TM4-6 PF06459.12 CDJ68341.1 - 5.3 6.8 23.9 6 6.6 23.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC53 PF10152.9 CDJ68341.1 - 5.5 7.4 25.6 6.3 7.2 25.6 1.0 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FAM60A PF15396.6 CDJ68341.1 - 5.8 6.9 18.6 6.7 6.6 18.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A GNAT_acetyltr_2 PF13718.6 CDJ68341.1 - 6.1 6.2 15.7 6.4 6.1 15.7 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 ATP11 PF06644.11 CDJ68341.1 - 6.2 6.5 24.1 7 6.4 24.1 1.0 1 0 0 1 1 1 0 ATP11 protein DUF4758 PF15950.5 CDJ68341.1 - 6.7 7.1 6.7 7.9 6.8 6.7 1.0 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein NARP1 PF12569.8 CDJ68341.1 - 7 5.4 23.2 8 5.2 23.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CLN3 PF02487.17 CDJ68341.1 - 8.3 5.3 20.1 8.7 5.3 20.1 1.0 1 0 0 1 1 1 0 CLN3 protein Velvet PF11754.8 CDJ68341.1 - 8.5 6.2 24.2 9.4 6.1 24.2 1.0 1 0 0 1 1 1 0 Velvet factor Presenilin PF01080.17 CDJ68341.1 - 8.7 5.0 29.1 10 4.7 29.1 1.0 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 CDJ68341.1 - 8.8 5.2 16.8 9.9 5.0 16.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ribosomal_S2 PF00318.20 CDJ68341.1 - 8.9 5.5 12.6 8.9 5.5 12.6 1.0 1 0 0 1 1 1 0 Ribosomal protein S2 Connexin PF00029.19 CDJ68341.1 - 9.1 6.0 21.3 9.8 5.9 21.3 1.0 1 0 0 1 1 1 0 Connexin CobT PF06213.12 CDJ68341.1 - 9.2 5.6 34.2 9.9 5.5 34.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4407 PF14362.6 CDJ68341.1 - 9.4 5.5 29.3 9.9 5.4 29.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Endostatin PF06482.11 CDJ68341.1 - 10 5.5 22.1 11 5.4 22.1 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SRP-alpha_N PF04086.13 CDJ68342.1 - 6.1 6.7 13.4 7.7 6.3 13.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pex24p PF06398.11 CDJ68343.1 - 0.044 12.8 0.7 0.063 12.2 0.7 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Trm112p PF03966.16 CDJ68344.1 - 1.9e-12 47.6 0.1 1.9e-12 47.6 0.1 2.4 2 0 0 2 2 2 1 Trm112p-like protein SR-25 PF10500.9 CDJ68344.1 - 0.00083 19.0 11.9 0.00083 19.0 11.9 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ68344.1 - 0.0052 16.8 27.5 0.0052 16.8 27.5 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ68344.1 - 0.028 15.1 17.7 0.028 15.1 17.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Activator_LAG-3 PF11498.8 CDJ68344.1 - 0.14 11.1 82.1 0.15 11.0 41.9 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 CCSAP PF15748.5 CDJ68344.1 - 0.16 12.2 20.9 0.02 15.1 12.6 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated VIT1 PF01988.19 CDJ68344.1 - 0.62 9.9 9.8 2.5 7.9 3.8 2.2 2 0 0 2 2 2 0 VIT family Neur_chan_memb PF02932.16 CDJ68344.1 - 1.7 8.6 16.4 1.2 9.2 9.4 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.13 CDJ68344.1 - 2 7.3 16.7 0.13 11.1 9.3 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Zip PF02535.22 CDJ68344.1 - 2.9 7.0 4.2 3.8 6.6 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.13 CDJ68344.1 - 5.4 5.9 19.9 8.6 5.3 19.4 1.6 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TERB2 PF15101.6 CDJ68344.1 - 5.9 6.9 27.9 4.2 7.4 2.8 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 O-antigen_lig PF13425.6 CDJ68344.1 - 7.3 5.3 4.6 10 4.8 4.6 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SLC12 PF03522.15 CDJ68344.1 - 7.8 5.4 20.7 2.2 7.2 14.2 2.1 2 0 0 2 2 2 0 Solute carrier family 12 SRAP PF02586.14 CDJ68345.1 - 1.1e-24 87.2 31.6 1.3e-19 70.6 31.6 3.2 1 1 0 1 1 1 1 SOS response associated peptidase (SRAP) MAT1 PF06391.13 CDJ68345.1 - 0.0041 17.0 10.1 0.0041 17.0 10.1 3.0 3 1 0 3 3 3 1 CDK-activating kinase assembly factor MAT1 SUIM_assoc PF16619.5 CDJ68345.1 - 0.056 13.5 0.5 0.056 13.5 0.5 7.4 3 2 2 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 BAF1_ABF1 PF04684.13 CDJ68345.1 - 0.088 11.9 32.1 0.34 9.9 21.7 2.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Tim54 PF11711.8 CDJ68345.1 - 0.75 8.5 33.8 0.22 10.3 3.3 2.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF2151 PF10221.9 CDJ68345.1 - 1.7 7.2 22.5 0.8 8.2 9.3 2.2 2 0 0 2 2 2 0 Cell cycle and development regulator CDC45 PF02724.14 CDJ68345.1 - 1.8 6.7 33.5 0.016 13.5 13.9 2.3 2 0 0 2 2 2 0 CDC45-like protein PA26 PF04636.13 CDJ68345.1 - 2.8 6.7 31.6 1.3 7.8 18.5 2.5 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) CLN3 PF02487.17 CDJ68345.1 - 5.8 5.9 26.0 2.3 7.2 1.7 2.5 2 0 0 2 2 2 0 CLN3 protein JAB PF01398.21 CDJ68346.1 - 3.3e-10 40.0 2.9 1.7e-09 37.6 0.0 2.6 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 CDJ68346.1 - 0.1 12.6 0.2 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) UCH PF00443.29 CDJ68347.1 - 0.091 12.2 0.0 0.091 12.2 0.0 4.5 3 1 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase N6_N4_Mtase PF01555.18 CDJ68347.1 - 0.41 10.3 2.4 6.6 6.4 0.1 2.9 3 2 0 3 3 3 0 DNA methylase RAP1 PF07218.11 CDJ68347.1 - 0.66 8.2 2.6 0.94 7.7 2.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SAPS PF04499.15 CDJ68347.1 - 7.1 5.3 17.8 0.68 8.6 6.5 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein EPL1 PF10513.9 CDJ68349.1 - 0.00029 21.3 8.2 0.0016 18.8 0.2 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like TFIIA PF03153.13 CDJ68349.1 - 0.0067 16.5 45.0 0.097 12.7 12.2 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit EOS1 PF12326.8 CDJ68349.1 - 0.083 12.8 8.5 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 N-glycosylation protein Pex14_N PF04695.13 CDJ68349.1 - 1.5 9.4 33.0 0.17 12.5 15.5 2.6 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 CDJ68349.1 - 2.2 6.5 32.6 0.17 10.2 13.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4228 PF14009.6 CDJ68349.1 - 2.5 8.4 15.1 1.8 8.9 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CPSF100_C PF13299.6 CDJ68349.1 - 3 8.0 17.2 0.87 9.8 7.6 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CDK5_activator PF03261.15 CDJ68349.1 - 4.1 6.8 13.0 0.75 9.3 5.3 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Spt20 PF12090.8 CDJ68349.1 - 6.1 6.4 52.9 2.8 7.5 14.2 2.1 2 0 0 2 2 2 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ68349.1 - 6.5 5.6 59.1 2.6 6.9 19.2 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 MRC1 PF09444.10 CDJ68349.1 - 6.6 7.2 18.3 1.7 9.1 6.8 2.3 2 0 0 2 2 2 0 MRC1-like domain Ndc1_Nup PF09531.10 CDJ68349.1 - 8 5.0 20.6 1.8 7.1 7.3 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup RskA PF10099.9 CDJ68349.1 - 9.1 6.5 68.9 0.02 15.2 10.3 4.2 2 2 2 4 4 4 0 Anti-sigma-K factor rskA NUDIX PF00293.28 CDJ68350.1 - 4.5e-06 26.7 0.0 6.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Macoilin PF09726.9 CDJ68350.1 - 0.099 11.2 2.5 0.12 10.9 2.5 1.2 1 0 0 1 1 1 0 Macoilin family Secretin_N_2 PF07655.13 CDJ68350.1 - 0.19 12.3 12.5 0.32 11.5 12.5 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain CCDC106 PF15794.5 CDJ68350.1 - 1.2 8.8 5.1 1.7 8.3 5.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 IBN_N PF03810.19 CDJ68352.1 - 5.9e-13 48.5 0.1 1e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain zf-CCCH PF00642.24 CDJ68353.1 - 3.1e-08 33.3 6.8 7.9e-08 32.0 6.8 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 CDJ68353.1 - 4e-05 23.5 8.8 0.00011 22.0 8.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ68353.1 - 0.00081 19.4 5.9 0.002 18.1 5.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 CDJ68353.1 - 0.027 14.5 8.3 0.073 13.2 8.3 1.8 1 0 0 1 1 1 0 Zinc finger domain zf-P11 PF03854.14 CDJ68353.1 - 1.2 8.9 9.2 0.096 12.4 3.2 2.1 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 CDJ68353.1 - 7.3 6.8 12.6 10 6.4 8.3 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Ank_2 PF12796.7 CDJ68354.1 - 9.1e-30 103.1 10.3 7.6e-13 48.9 1.9 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ68354.1 - 8.3e-21 73.5 4.5 5.2e-06 26.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CDJ68354.1 - 3.3e-19 66.9 2.1 6.2e-05 23.1 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 CDJ68354.1 - 1e-17 64.2 1.6 3.2e-10 40.3 0.2 3.2 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ68354.1 - 8.5e-14 51.5 4.2 2.1e-06 27.9 0.2 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF2384 PF09722.10 CDJ68354.1 - 0.083 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) TBCC PF07986.12 CDJ68355.1 - 6e-13 48.6 0.2 6e-13 48.6 0.2 1.9 2 0 0 2 2 2 1 Tubulin binding cofactor C CAF1 PF04857.20 CDJ68355.1 - 0.0012 18.1 0.0 0.22 10.7 0.0 2.4 1 1 1 2 2 2 2 CAF1 family ribonuclease Spt20 PF12090.8 CDJ68355.1 - 0.0045 16.6 11.1 0.0045 16.6 11.1 4.3 4 1 0 4 4 4 1 Spt20 family Neur_chan_memb PF02932.16 CDJ68355.1 - 2.4 8.2 16.7 2.7 8.0 1.5 3.0 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF1645 PF07816.11 CDJ68355.1 - 2.6 8.6 19.7 0.024 15.2 7.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) Pkinase PF00069.25 CDJ68357.1 - 5.4e-06 26.0 0.1 2.2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain DUF2722 PF10846.8 CDJ68357.1 - 4e-05 22.8 0.1 6.1e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ68357.1 - 0.00053 19.7 8.0 0.00078 19.1 8.0 1.3 1 0 0 1 1 1 1 Spt20 family Protamine_P2 PF00841.19 CDJ68357.1 - 4.1 8.0 8.1 6.6 7.3 8.1 1.3 1 0 0 1 1 1 0 Sperm histone P2 Fumble PF03630.14 CDJ68358.1 - 4.8e-76 256.1 0.1 8.4e-71 238.8 0.0 2.6 3 0 0 3 3 3 2 Fumble Coatomer_WDAD PF04053.14 CDJ68358.1 - 0.083 11.9 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Suf PF05843.14 CDJ68358.1 - 0.5 10.3 4.4 1.3 8.9 4.4 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GET2 PF08690.10 CDJ68358.1 - 1.1 8.9 7.9 2 8.0 7.9 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 XK-related PF09815.9 CDJ68359.1 - 0.087 11.9 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 XK-related protein Mtc PF03820.17 CDJ68360.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Tricarboxylate carrier DUF872 PF05915.12 CDJ68360.1 - 0.18 12.0 0.3 26 5.0 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) WD40 PF00400.32 CDJ68364.1 - 0.0012 19.6 0.1 24 6.0 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Ribosomal_60s PF00428.19 CDJ68364.1 - 0.015 15.9 9.7 0.015 15.9 9.7 13.5 9 2 2 11 11 11 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ68364.1 - 0.034 13.8 24.2 0.012 15.3 13.4 2.3 2 0 0 2 2 2 0 Spt20 family Nha1_C PF08619.10 CDJ68364.1 - 0.56 9.4 9.9 0.037 13.2 2.8 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Presenilin PF01080.17 CDJ68364.1 - 2 7.1 4.7 1.1 8.0 0.9 2.0 2 0 0 2 2 2 0 Presenilin Exonuc_VII_L PF02601.15 CDJ68365.1 - 0.00019 21.1 10.1 0.0002 21.0 10.1 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF874 PF05917.11 CDJ68365.1 - 0.01 14.9 6.7 0.013 14.6 6.7 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) V_ATPase_I PF01496.19 CDJ68365.1 - 0.081 10.8 5.4 0.098 10.6 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCU PF04678.13 CDJ68365.1 - 0.26 11.4 5.8 0.37 10.9 5.8 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Pro_CA PF00484.19 CDJ68365.1 - 0.36 11.1 4.9 0.5 10.7 4.9 1.3 1 0 0 1 1 1 0 Carbonic anhydrase DUF3552 PF12072.8 CDJ68365.1 - 0.67 9.3 18.9 1.1 8.7 18.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) EMC3_TMCO1 PF01956.16 CDJ68365.1 - 0.76 9.5 7.2 1.2 8.8 7.2 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like LMBR1 PF04791.16 CDJ68365.1 - 1.7 7.4 4.6 2.1 7.1 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TFIIA PF03153.13 CDJ68365.1 - 2.3 8.1 34.6 3.9 7.4 34.6 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FapA PF03961.13 CDJ68365.1 - 3.3 6.2 9.6 4.2 5.9 9.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4175 PF13779.6 CDJ68365.1 - 4.1 5.2 28.6 4.7 5.0 28.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SOG2 PF10428.9 CDJ68366.1 - 0.75 8.9 9.1 0.85 8.7 9.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 CDJ68366.1 - 3.7 7.4 11.8 3.7 7.4 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_A21 PF03566.13 CDJ68367.1 - 0.3 9.3 1.4 0.41 8.9 1.4 1.1 1 0 0 1 1 1 0 Peptidase family A21 G-patch PF01585.23 CDJ68368.1 - 0.00029 20.7 1.8 0.00029 20.7 1.8 2.4 2 0 0 2 2 2 1 G-patch domain C_GCAxxG_C_C PF09719.10 CDJ68368.1 - 0.0054 17.0 4.7 0.0054 17.0 4.7 3.5 3 0 0 3 3 3 1 Putative redox-active protein (C_GCAxxG_C_C) DUF1635 PF07795.11 CDJ68368.1 - 0.0075 16.2 11.0 0.0075 16.2 11.0 9.2 7 2 3 10 10 10 2 Protein of unknown function (DUF1635) RskA PF10099.9 CDJ68368.1 - 0.64 10.3 125.3 0.072 13.4 4.0 7.9 3 2 4 7 7 7 0 Anti-sigma-K factor rskA Cons_hypoth95 PF03602.15 CDJ68369.1 - 3.6e-06 26.7 0.3 3.6e-06 26.7 0.3 2.2 2 1 0 2 2 1 1 Conserved hypothetical protein 95 MTS PF05175.14 CDJ68369.1 - 3.8e-06 26.6 0.5 7.7e-06 25.6 0.5 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CDJ68369.1 - 6.9e-06 25.7 1.6 6.9e-06 25.7 1.6 2.5 3 1 0 3 3 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CDJ68369.1 - 7.5e-06 25.9 0.7 7.5e-06 25.9 0.7 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ68369.1 - 8.9e-05 23.1 2.4 0.0015 19.2 0.3 2.9 1 1 1 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 CDJ68369.1 - 0.00016 21.5 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein SUIM_assoc PF16619.5 CDJ68369.1 - 0.00056 19.9 0.0 0.00056 19.9 0.0 6.6 3 2 0 3 3 2 1 Unstructured region C-term to UIM in Ataxin3 Methyltransf_16 PF10294.9 CDJ68369.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase DOT1 PF08123.13 CDJ68369.1 - 0.16 11.5 0.3 0.28 10.7 0.3 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Neur_chan_memb PF02932.16 CDJ68369.1 - 0.6 10.1 6.5 6.4 6.8 3.8 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.6 CDJ68369.1 - 1.3 9.2 12.2 11 6.1 8.9 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Methyltransf_12 PF08242.12 CDJ68369.1 - 1.4 9.7 7.9 2.2 9.1 0.0 3.3 3 0 0 3 3 3 0 Methyltransferase domain Band_3_cyto PF07565.13 CDJ68369.1 - 7.1 6.3 14.6 7.6 6.3 0.1 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain AAA_12 PF13087.6 CDJ68370.1 - 3.3e-27 95.4 0.1 6.1e-27 94.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain SUIM_assoc PF16619.5 CDJ68370.1 - 0.00034 20.6 0.1 0.0011 19.0 0.0 2.0 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ68370.1 - 0.0028 18.0 6.9 0.0028 18.0 6.9 3.2 1 1 2 3 3 3 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ68372.1 - 0.0029 16.6 0.1 0.0029 16.6 0.1 12.4 14 1 0 14 14 14 3 Protein of unknown function (DUF2722) Connexin PF00029.19 CDJ68372.1 - 0.3 10.8 4.3 0.98 9.1 2.0 2.6 2 0 0 2 2 2 0 Connexin Mit_KHE1 PF10173.9 CDJ68372.1 - 1.6 8.8 6.7 0.86 9.7 1.4 3.1 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Hid1 PF12722.7 CDJ68372.1 - 1.8 6.6 12.3 7.7 4.5 7.7 2.6 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein AAA_22 PF13401.6 CDJ68372.1 - 6 7.1 9.4 2 8.7 0.4 4.5 3 0 0 3 3 3 0 AAA domain Zn_peptidase PF04228.13 CDJ68374.1 - 0.18 11.2 0.3 11 5.4 0.1 2.3 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Apt1 PF10351.9 CDJ68374.1 - 1.5 7.6 10.4 1.9 7.2 10.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2207 PF09972.9 CDJ68374.1 - 2 7.1 4.0 9.4 4.9 1.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TFIIA PF03153.13 CDJ68375.1 - 0.023 14.7 16.1 0.029 14.4 16.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MDMPI_N PF11716.8 CDJ68375.1 - 0.053 14.2 1.3 0.053 14.2 1.3 3.4 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain SPT6_acidic PF14632.6 CDJ68376.1 - 3.5e-09 37.1 12.0 3.5e-09 37.1 12.0 6.4 2 1 2 4 4 4 1 Acidic N-terminal SPT6 Androgen_recep PF02166.16 CDJ68377.1 - 5.4 5.7 18.3 0.83 8.4 14.6 1.6 2 0 0 2 2 2 0 Androgen receptor DUF572 PF04502.13 CDJ68378.1 - 3.6e-32 112.3 45.9 2e-31 109.9 31.7 2.9 1 1 1 2 2 2 1 Family of unknown function (DUF572) Atx10homo_assoc PF09759.9 CDJ68378.1 - 0.0019 18.2 0.0 0.0019 18.2 0.0 3.5 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain DUF866 PF05907.13 CDJ68378.1 - 0.31 10.9 4.5 0.082 12.8 0.5 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) FA_desaturase PF00487.24 CDJ68378.1 - 0.38 10.6 1.1 0.87 9.4 0.0 2.0 2 0 0 2 2 2 0 Fatty acid desaturase DUF4179 PF13786.6 CDJ68378.1 - 0.79 10.2 10.2 9.8 6.7 1.4 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) AAA_24 PF13479.6 CDJ68378.1 - 3.3 7.4 4.4 1.1 8.9 0.9 2.0 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 CDJ68379.1 - 4.6e-72 242.5 0.0 6.2e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ68379.1 - 4.6e-29 101.5 0.0 7e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CBM_20 PF00686.19 CDJ68379.1 - 1.1e-12 47.7 0.0 1.7e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain EF-hand_7 PF13499.6 CDJ68379.1 - 5.7e-11 42.7 0.0 3.3e-08 33.9 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ68379.1 - 4e-09 35.7 0.0 0.0026 17.6 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 CDJ68379.1 - 8.1e-09 34.4 0.0 0.007 15.8 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDJ68379.1 - 2.3e-07 30.5 0.1 0.039 13.8 0.0 3.4 1 1 2 3 3 3 3 EF-hand domain pair Kdo PF06293.14 CDJ68379.1 - 8.6e-05 22.0 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_5 PF13202.6 CDJ68379.1 - 0.0001 21.6 0.2 0.29 10.7 0.0 2.5 2 0 0 2 2 2 2 EF hand APH PF01636.23 CDJ68379.1 - 0.0088 16.0 0.2 0.03 14.3 0.2 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ68379.1 - 0.19 11.0 0.1 0.56 9.5 0.0 1.8 2 1 0 2 2 2 0 Kinase-like MDMPI_N PF11716.8 CDJ68379.1 - 0.26 12.0 10.9 0.07 13.8 7.5 1.8 2 0 0 2 2 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain TSP_1 PF00090.19 CDJ68381.1 - 0.001 19.2 0.4 0.0026 18.0 0.4 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain Radial_spoke PF04712.12 CDJ68383.1 - 7.5e-08 31.8 0.0 7.8e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Radial spokehead-like protein Flu_PB1 PF00602.17 CDJ68383.1 - 0.076 11.1 0.0 0.099 10.7 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 Rpr2 PF04032.16 CDJ68384.1 - 6.7 7.1 8.4 15 5.9 1.0 3.1 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RDM PF11002.8 CDJ68385.1 - 0.13 12.3 0.8 0.5 10.4 0.1 2.3 2 0 0 2 2 2 0 RFPL defining motif (RDM) F-box PF00646.33 CDJ68386.1 - 0.00035 20.4 0.2 0.001 18.9 0.2 1.8 1 0 0 1 1 1 1 F-box domain TFIIA PF03153.13 CDJ68386.1 - 5.3 6.9 24.7 8.7 6.2 15.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Rad50_zn_hook PF04423.14 CDJ68387.1 - 0.014 15.3 1.0 0.023 14.5 1.0 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif Arm PF00514.23 CDJ68389.1 - 2.2e-07 30.7 3.8 0.0055 16.7 0.1 4.1 2 1 2 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDJ68389.1 - 0.00011 22.5 6.8 0.015 15.6 1.3 3.3 1 1 1 3 3 3 1 HEAT repeats Cnd1 PF12717.7 CDJ68389.1 - 0.00031 20.8 0.1 0.64 10.0 0.2 2.2 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDJ68389.1 - 0.13 12.6 3.3 13 6.4 0.0 3.4 3 1 0 3 3 3 0 HEAT repeat Peptidase_M91 PF14891.6 CDJ68389.1 - 0.18 12.1 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 Effector protein ApoC-I PF04691.12 CDJ68389.1 - 0.23 11.4 0.7 5.3 7.1 0.2 2.2 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) HEAT_EZ PF13513.6 CDJ68389.1 - 0.33 11.5 3.6 24 5.6 0.3 3.1 2 1 0 2 2 2 0 HEAT-like repeat Robl_LC7 PF03259.17 CDJ68390.1 - 3.1e-05 23.7 0.0 3.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CDJ68390.1 - 0.0039 17.1 0.0 0.004 17.0 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 FBP_C PF16571.5 CDJ68391.1 - 0.13 11.8 0.5 0.26 10.8 0.5 1.5 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger DUF4200 PF13863.6 CDJ68392.1 - 1.1e-14 54.8 3.3 1.1e-14 54.8 3.3 3.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) Med11 PF10280.9 CDJ68392.1 - 0.0023 18.4 5.8 0.0023 18.4 5.8 2.0 2 1 0 2 2 2 1 Mediator complex protein Cast PF10174.9 CDJ68392.1 - 0.19 9.9 29.6 0.096 10.9 7.7 3.0 1 1 2 3 3 3 0 RIM-binding protein of the cytomatrix active zone COG2 PF06148.11 CDJ68392.1 - 0.81 9.8 10.9 4.1 7.5 0.0 3.6 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 HSBP1 PF06825.12 CDJ68392.1 - 4.3 7.3 9.1 0.71 9.8 0.1 3.4 2 2 0 2 2 2 0 Heat shock factor binding protein 1 Borrelia_P83 PF05262.11 CDJ68392.1 - 9.7 4.6 23.6 12 4.3 23.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DivIC PF04977.15 CDJ68393.1 - 1.8e-05 24.4 0.6 2.8e-05 23.8 0.6 1.3 1 0 0 1 1 1 1 Septum formation initiator HALZ PF02183.18 CDJ68393.1 - 0.00034 20.8 2.0 0.00082 19.5 2.0 1.6 1 1 0 1 1 1 1 Homeobox associated leucine zipper TMF_DNA_bd PF12329.8 CDJ68393.1 - 0.00038 20.4 1.4 0.00053 19.9 1.4 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 CDJ68393.1 - 0.0004 20.4 1.9 0.0006 19.9 1.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 CDJ68393.1 - 0.00079 19.7 0.1 0.0016 18.7 0.1 1.5 1 1 0 1 1 1 1 TSC-22/dip/bun family DUF2968 PF11180.8 CDJ68393.1 - 0.0011 18.6 0.4 0.0013 18.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Nnf1 PF03980.14 CDJ68393.1 - 0.0013 19.1 0.1 0.0015 18.9 0.1 1.3 1 0 0 1 1 1 1 Nnf1 bZIP_2 PF07716.15 CDJ68393.1 - 0.0014 18.7 3.1 0.003 17.6 3.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Cnn_1N PF07989.11 CDJ68393.1 - 0.0015 18.7 0.1 0.002 18.2 0.1 1.3 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 ADIP PF11559.8 CDJ68393.1 - 0.0038 17.3 1.0 0.0059 16.7 1.0 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF4140 PF13600.6 CDJ68393.1 - 0.0064 16.9 0.1 0.0064 16.9 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 CDJ68393.1 - 0.0075 16.7 3.0 0.011 16.1 3.0 1.3 1 0 0 1 1 1 1 Cell division protein ZapB APG6_N PF17675.1 CDJ68393.1 - 0.0077 16.8 0.2 0.0077 16.8 0.2 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region GIT_CC PF16559.5 CDJ68393.1 - 0.0085 15.9 1.6 0.015 15.2 1.6 1.4 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2730 PF10805.8 CDJ68393.1 - 0.0087 16.1 0.2 0.0094 16.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DUF3450 PF11932.8 CDJ68393.1 - 0.0097 15.2 1.2 0.013 14.8 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) JIP_LZII PF16471.5 CDJ68393.1 - 0.011 15.9 1.7 0.032 14.4 1.7 1.9 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Csm1_N PF18504.1 CDJ68393.1 - 0.013 15.8 1.9 0.02 15.2 1.9 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain FlaC_arch PF05377.11 CDJ68393.1 - 0.017 15.5 0.8 0.14 12.5 0.5 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 CDJ68393.1 - 0.021 13.7 0.2 0.022 13.7 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 CDJ68393.1 - 0.028 13.8 0.1 0.028 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phasin PF05597.11 CDJ68393.1 - 0.029 14.4 0.2 0.25 11.3 0.0 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Shugoshin_N PF07558.11 CDJ68393.1 - 0.048 13.5 0.4 0.097 12.6 0.4 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Mto2_bdg PF12808.7 CDJ68393.1 - 0.053 13.8 0.4 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Seryl_tRNA_N PF02403.22 CDJ68393.1 - 0.054 13.7 1.5 0.073 13.3 1.3 1.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MbeD_MobD PF04899.12 CDJ68393.1 - 0.059 13.5 0.8 0.13 12.4 0.6 1.6 2 0 0 2 2 1 0 MbeD/MobD like YabA PF06156.13 CDJ68393.1 - 0.12 13.1 0.4 0.17 12.5 0.4 1.3 1 1 0 1 1 1 0 Initiation control protein YabA TRAF_BIRC3_bd PF16673.5 CDJ68393.1 - 0.17 11.7 2.2 0.24 11.2 1.4 1.5 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF1843 PF08898.10 CDJ68393.1 - 0.27 11.8 3.0 3.5 8.2 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) AP2 PF00847.20 CDJ68395.1 - 1.7e-11 44.1 0.2 4.9e-11 42.7 0.2 1.8 1 0 0 1 1 1 1 AP2 domain TFIIA PF03153.13 CDJ68395.1 - 0.57 10.1 9.1 1.2 9.0 9.1 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRP3 PF08572.10 CDJ68395.1 - 0.77 9.4 5.5 9.5 5.9 3.5 2.3 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) AP2 PF00847.20 CDJ68396.1 - 8.2e-10 38.8 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 AP2 domain RNA_pol_Rpc4 PF05132.14 CDJ68397.1 - 4.4e-14 53.1 0.1 4.4e-14 53.1 0.1 2.5 2 1 0 2 2 2 1 RNA polymerase III RPC4 Rtt106 PF08512.12 CDJ68398.1 - 1.8e-24 85.9 1.2 9.5e-24 83.6 0.1 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like POB3_N PF17292.2 CDJ68398.1 - 1.4e-23 83.1 0.3 1e-22 80.4 0.1 2.4 2 1 1 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 CDJ68398.1 - 1.7e-21 75.9 0.6 4.4e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) YL1 PF05764.13 CDJ68398.1 - 0.0056 16.8 15.6 0.0056 16.8 15.6 1.6 2 0 0 2 2 2 1 YL1 nuclear protein PBP1_TM PF14812.6 CDJ68398.1 - 4.6 7.7 10.8 14 6.1 10.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDK2AP PF09806.9 CDJ68399.1 - 3.7 7.5 0.0 3.7 7.5 0.0 6.8 6 2 0 6 6 6 0 Cyclin-dependent kinase 2-associated protein Vps35 PF03635.17 CDJ68400.1 - 4.3e-233 776.0 0.1 1.2e-231 771.2 0.1 2.6 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RNA_pol_Rpb2_6 PF00562.28 CDJ68401.1 - 4.8e-118 394.6 0.0 6.4e-118 394.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDJ68401.1 - 2.6e-43 147.9 0.0 3.7e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CDJ68401.1 - 3.6e-32 110.6 0.3 7.6e-32 109.6 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 CDJ68401.1 - 8e-20 70.8 0.0 1.7e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 CDJ68401.1 - 3.2e-19 69.0 0.0 5.9e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 CDJ68401.1 - 5.7e-16 58.7 0.0 1.2e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 CDJ68401.1 - 1.2e-06 29.0 0.8 3.3e-06 27.5 0.8 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zn-ribbon_14 PF16503.5 CDJ68401.1 - 0.36 10.4 2.4 1.2 8.6 2.4 2.0 1 0 0 1 1 1 0 Zinc-ribbon Dpy-30 PF05186.13 CDJ68402.1 - 5.3e-12 45.2 0.1 9.7e-12 44.4 0.1 1.4 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 CDJ68402.1 - 1e-08 35.4 0.0 0.034 14.3 0.0 3.3 2 1 1 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 CDJ68402.1 - 2.2e-06 28.1 3.2 0.00015 22.2 0.0 3.9 3 1 0 4 4 4 1 AAA domain AAA_18 PF13238.6 CDJ68402.1 - 2.4e-05 24.9 1.1 0.00048 20.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain SPX PF03105.19 CDJ68402.1 - 3.5e-05 23.9 2.2 3.5e-05 23.9 2.2 2.3 2 1 0 2 2 2 1 SPX domain AAA_28 PF13521.6 CDJ68402.1 - 0.00018 21.8 1.4 0.00018 21.8 1.4 3.5 4 0 0 4 4 2 1 AAA domain AAA_33 PF13671.6 CDJ68402.1 - 0.0013 18.9 2.1 0.01 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ68402.1 - 0.0014 19.0 0.4 0.0014 19.0 0.4 3.9 3 1 0 3 3 2 1 AAA ATPase domain 6PF2K PF01591.18 CDJ68402.1 - 0.0015 17.8 0.0 2.7 7.2 0.0 2.9 3 0 0 3 3 3 2 6-phosphofructo-2-kinase MID_MedPIWI PF18296.1 CDJ68402.1 - 0.0017 18.2 8.0 0.086 12.6 0.1 2.5 2 0 0 2 2 2 2 MID domain of medPIWI Mg_chelatase PF01078.21 CDJ68402.1 - 0.0026 17.2 0.1 0.0055 16.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CDJ68402.1 - 0.0052 17.1 0.1 0.046 14.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 CDJ68402.1 - 0.0079 16.2 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CDJ68402.1 - 0.0087 15.8 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 CDJ68402.1 - 0.0099 15.6 0.6 0.0099 15.6 0.6 2.2 2 0 0 2 2 1 1 Cytidylate kinase AAA_23 PF13476.6 CDJ68402.1 - 0.022 15.3 9.2 1.2 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CDJ68402.1 - 0.026 14.5 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 CDJ68402.1 - 0.034 13.9 0.0 0.085 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CDJ68402.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 CDJ68402.1 - 0.06 13.8 0.0 0.06 13.8 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ68402.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SKI PF01202.22 CDJ68402.1 - 0.075 13.2 1.5 0.6 10.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_11 PF13086.6 CDJ68402.1 - 0.08 12.7 7.4 3.7 7.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain KTI12 PF08433.10 CDJ68402.1 - 0.094 12.2 0.0 0.094 12.2 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF4667 PF15700.5 CDJ68402.1 - 0.1 12.7 22.4 0.055 13.6 7.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) PRK PF00485.18 CDJ68402.1 - 0.11 12.2 0.3 0.22 11.2 0.3 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GlcNAc-1_reg PF18440.1 CDJ68402.1 - 0.11 12.7 0.1 5.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain Zeta_toxin PF06414.12 CDJ68402.1 - 0.81 8.9 0.0 0.81 8.9 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin KAP_NTPase PF07693.14 CDJ68402.1 - 3.2 6.9 5.4 16 4.6 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain DUF4570 PF15134.6 CDJ68402.1 - 4.7 7.3 15.6 2.9 8.0 11.6 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4570) Filament_head PF04732.14 CDJ68402.1 - 5.9 7.8 35.7 2.2 9.2 6.4 2.6 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Spt20 PF12090.8 CDJ68403.1 - 0.01 15.5 4.2 0.017 14.8 4.2 1.3 1 0 0 1 1 1 0 Spt20 family Gaa1 PF04114.14 CDJ68403.1 - 0.015 14.3 12.0 0.019 14.0 12.0 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component MIG-14_Wnt-bd PF06664.12 CDJ68403.1 - 0.092 11.9 11.7 0.11 11.6 11.7 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion SPX PF03105.19 CDJ68403.1 - 0.38 10.6 10.9 0.54 10.1 10.9 1.2 1 0 0 1 1 1 0 SPX domain LMF1 PF06762.14 CDJ68403.1 - 0.46 9.5 3.3 0.49 9.4 3.3 1.1 1 0 0 1 1 1 0 Lipase maturation factor RskA PF10099.9 CDJ68403.1 - 0.71 10.1 28.4 0.17 12.2 2.0 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF1129 PF06570.11 CDJ68403.1 - 4.3 6.8 10.6 8 5.9 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Cation_ATPase_C PF00689.21 CDJ68403.1 - 6.3 6.5 16.2 10 5.8 16.2 1.5 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus RrnaAD PF00398.20 CDJ68404.1 - 7.9e-09 35.0 0.0 1.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF4667 PF15700.5 CDJ68404.1 - 0.025 14.7 7.7 0.036 14.2 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Peptidase_S64 PF08192.11 CDJ68404.1 - 0.036 12.6 5.6 0.044 12.3 5.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Plasmodium_Vir PF05795.11 CDJ68404.1 - 0.13 11.7 0.7 0.16 11.4 0.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4834 PF16118.5 CDJ68404.1 - 0.15 13.1 0.4 0.15 13.1 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4598 PF15370.6 CDJ68404.1 - 0.15 12.5 2.5 16 6.0 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) TFIIA PF03153.13 CDJ68404.1 - 0.19 11.7 8.7 0.29 11.1 8.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ68404.1 - 0.55 9.7 6.1 0.74 9.3 6.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ68404.1 - 1.6 7.2 6.3 2 6.9 6.3 1.1 1 0 0 1 1 1 0 Macoilin family TAF4 PF05236.14 CDJ68404.1 - 2.1 8.0 16.8 7.4 6.2 16.8 1.7 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Presenilin PF01080.17 CDJ68404.1 - 3.6 6.3 4.7 4.7 5.9 4.7 1.1 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ68404.1 - 3.8 7.1 26.0 6.8 6.2 26.0 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4692 PF15763.5 CDJ68404.1 - 8 6.9 11.3 0.44 11.0 4.9 1.8 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Biotin_lipoyl PF00364.22 CDJ68405.1 - 2.3e-19 69.0 0.5 1.9e-17 62.8 0.1 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 CDJ68405.1 - 9e-10 38.7 0.3 3.9e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 e3 binding domain 2-oxoacid_dh PF00198.23 CDJ68405.1 - 1.1e-09 38.1 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) SR-25 PF10500.9 CDJ68405.1 - 0.015 14.9 11.5 0.52 9.9 1.5 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MRP-S32 PF10210.9 CDJ68405.1 - 0.071 13.7 1.8 0.16 12.5 1.8 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 DUF4667 PF15700.5 CDJ68405.1 - 0.076 13.1 11.7 0.37 10.8 6.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) DUF4834 PF16118.5 CDJ68405.1 - 0.094 13.7 5.6 0.11 13.5 4.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ68405.1 - 0.18 11.4 18.7 0.38 10.3 18.7 1.4 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ68405.1 - 2 7.3 20.7 0.064 12.2 14.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Pap_E4 PF02711.14 CDJ68405.1 - 2.3 9.3 10.0 1.7 9.6 7.1 2.1 2 0 0 2 2 2 0 E4 protein Rtf2 PF04641.12 CDJ68405.1 - 3.2 7.1 11.4 5.9 6.2 1.0 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger DUF4598 PF15370.6 CDJ68405.1 - 5.5 7.5 8.6 2.7 8.5 3.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) Ashwin PF15323.6 CDJ68405.1 - 7.4 6.5 14.5 6.2 6.8 0.8 2.4 1 1 1 2 2 2 0 Developmental protein Presenilin PF01080.17 CDJ68405.1 - 9.5 4.9 8.7 0.67 8.7 4.1 1.4 2 0 0 2 2 2 0 Presenilin Mago_nashi PF02792.14 CDJ68406.1 - 6.3e-23 81.5 5.0 6.7e-23 81.4 5.0 1.0 1 0 0 1 1 1 1 Mago nashi protein F5_F8_type_C PF00754.25 CDJ68407.1 - 1.9e-16 60.3 0.0 1.5e-10 41.3 0.0 2.3 2 0 0 2 2 2 2 F5/8 type C domain Ricin_B_lectin PF00652.22 CDJ68407.1 - 0.064 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Laminin_N PF00055.17 CDJ68407.1 - 0.18 11.4 0.0 0.56 9.8 0.0 1.7 1 1 1 2 2 2 0 Laminin N-terminal (Domain VI) DUF4632 PF15451.6 CDJ68408.1 - 0.031 14.3 0.1 0.051 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF5585 PF17823.1 CDJ68409.1 - 8.6 5.2 20.4 11 4.8 20.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5585) CTNNBL PF08216.11 CDJ68410.1 - 4.2e-09 36.5 1.4 6.2e-09 36.0 1.4 1.2 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear FTCD_C PF04961.12 CDJ68410.1 - 0.0044 16.8 3.9 0.0055 16.5 3.9 1.2 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase Herpes_U30 PF04523.13 CDJ68410.1 - 0.051 11.5 0.1 0.059 11.2 0.1 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 HARE-HTH PF05066.13 CDJ68410.1 - 0.2 12.0 0.8 0.37 11.2 0.8 1.4 1 1 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain PALP PF00291.25 CDJ68411.1 - 5e-14 52.4 0.1 2.4e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme SR-25 PF10500.9 CDJ68411.1 - 0.0059 16.3 6.6 0.0087 15.7 6.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ68411.1 - 0.08 13.3 8.1 0.17 12.2 8.1 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain IMUP PF15761.5 CDJ68411.1 - 0.13 12.9 5.0 0.24 12.1 5.0 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Dehydrin PF00257.19 CDJ68411.1 - 0.16 12.6 2.7 0.14 12.7 1.5 1.6 2 0 0 2 2 2 0 Dehydrin Pkinase PF00069.25 CDJ68412.1 - 1.2e-22 80.6 0.0 6e-21 75.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ68412.1 - 2.1e-12 46.9 0.0 3.4e-12 46.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ68412.1 - 0.00028 20.3 0.0 0.00054 19.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ68412.1 - 0.00034 20.6 1.1 0.0009 19.2 1.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ68412.1 - 0.0031 16.9 0.0 0.024 13.9 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDJ68412.1 - 0.0053 15.6 0.1 0.0085 14.9 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase TALPID3 PF15324.6 CDJ68412.1 - 0.022 12.5 0.1 0.029 12.1 0.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Ribosomal_60s PF00428.19 CDJ68412.1 - 0.045 14.3 2.7 0.09 13.4 2.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein CRM1_repeat_2 PF18784.1 CDJ68412.1 - 0.055 13.1 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 FTA2 PF13095.6 CDJ68412.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 IMUP PF15761.5 CDJ68412.1 - 0.16 12.6 6.7 0.28 11.9 6.7 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Haspin_kinase PF12330.8 CDJ68412.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CDJ68412.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 CDJ68412.1 - 0.24 11.0 0.0 0.39 10.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family SR-25 PF10500.9 CDJ68412.1 - 1.1 8.8 6.9 1.7 8.2 6.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ68413.1 - 0.0015 18.2 23.6 0.016 14.8 4.8 2.2 2 0 0 2 2 2 2 Spt20 family RskA PF10099.9 CDJ68413.1 - 0.0017 18.7 12.3 0.0017 18.7 12.3 5.0 3 2 2 5 5 5 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ68413.1 - 0.0024 16.9 12.2 0.019 13.9 0.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ68413.1 - 0.0038 17.3 24.4 0.0083 16.2 3.8 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Neuregulin PF02158.15 CDJ68413.1 - 0.24 10.7 9.2 0.27 10.5 0.3 2.2 2 0 0 2 2 2 0 Neuregulin intracellular region DUF3371 PF11851.8 CDJ68413.1 - 2.2 9.4 10.5 16 6.6 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) WBP-1 PF11669.8 CDJ68413.1 - 6 7.6 11.9 8.6 7.1 4.4 3.2 3 0 0 3 3 3 0 WW domain-binding protein 1 zf-CSL PF05207.13 CDJ68414.1 - 1.8e-14 53.2 0.0 2.7e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 CSL zinc finger Hamartin PF04388.12 CDJ68414.1 - 0.88 8.2 4.8 0.91 8.1 4.8 1.1 1 0 0 1 1 1 0 Hamartin protein Rad60-SLD PF11976.8 CDJ68415.1 - 3.3e-21 74.9 0.1 6.7e-21 73.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDJ68415.1 - 1.9e-10 40.4 0.2 2.8e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin family DUF2890 PF11081.8 CDJ68415.1 - 0.14 12.2 3.8 0.22 11.7 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ribosomal_60s PF00428.19 CDJ68415.1 - 6 7.5 8.3 2 9.0 4.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Elf1 PF05129.13 CDJ68416.1 - 0.15 12.1 4.5 0.64 10.1 4.1 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Spt20 PF12090.8 CDJ68417.1 - 0.023 14.3 4.5 0.028 14.1 4.5 1.2 1 0 0 1 1 1 0 Spt20 family Lin-8 PF03353.15 CDJ68417.1 - 0.16 11.5 2.8 0.17 11.4 2.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ68417.1 - 1.3 8.8 8.7 1.6 8.6 8.7 1.1 1 0 0 1 1 1 0 SPX domain RskA PF10099.9 CDJ68417.1 - 1.6 9.0 24.9 1.1 9.5 13.2 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Sterol-sensing PF12349.8 CDJ68418.1 - 2.3e-06 27.5 2.3 6.9e-06 26.0 2.3 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation SR-25 PF10500.9 CDJ68418.1 - 5.1e-05 23.0 5.1 5.1e-05 23.0 5.1 6.0 5 0 0 5 5 5 1 Nuclear RNA-splicing-associated protein Patched PF02460.18 CDJ68418.1 - 0.00086 17.5 3.2 0.0088 14.2 1.5 2.7 3 0 0 3 3 3 1 Patched family SUIM_assoc PF16619.5 CDJ68418.1 - 0.0078 16.3 0.2 0.0078 16.3 0.2 9.7 9 1 0 9 9 9 3 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ68419.1 - 0.0015 18.9 6.0 0.0019 18.5 6.0 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ68419.1 - 0.083 13.4 3.4 0.14 12.6 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF3138 PF11336.8 CDJ68419.1 - 2.5 6.6 8.3 3.3 6.2 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Myc_N PF01056.18 CDJ68422.1 - 5.4e-05 23.3 5.6 5.8e-05 23.2 5.6 1.2 1 0 0 1 1 1 1 Myc amino-terminal region Mitofilin PF09731.9 CDJ68422.1 - 0.00044 19.2 9.9 0.00053 19.0 9.9 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF3295 PF11702.8 CDJ68422.1 - 0.0013 18.2 9.6 0.0014 18.1 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) SR-25 PF10500.9 CDJ68422.1 - 0.0022 17.7 11.0 0.0026 17.4 11.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ARA70 PF12489.8 CDJ68422.1 - 0.0023 18.1 9.0 0.0034 17.6 9.0 1.3 1 0 0 1 1 1 1 Nuclear coactivator IMUP PF15761.5 CDJ68422.1 - 0.003 18.2 7.2 0.0061 17.2 7.2 1.5 1 0 0 1 1 1 1 Immortalisation up-regulated protein DUF5586 PF17824.1 CDJ68422.1 - 0.0049 16.0 0.0 0.0049 16.0 0.0 2.1 1 1 0 2 2 2 1 Family of unknown function (DUF5586) NOA36 PF06524.12 CDJ68422.1 - 0.011 15.1 7.5 0.014 14.7 7.5 1.1 1 0 0 1 1 1 0 NOA36 protein PRTP PF01366.18 CDJ68422.1 - 0.012 13.7 3.4 0.013 13.5 3.4 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Dpy-30 PF05186.13 CDJ68422.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Dpy-30 motif Presenilin PF01080.17 CDJ68422.1 - 0.021 13.6 9.6 0.024 13.4 9.6 1.1 1 0 0 1 1 1 0 Presenilin M_domain PF12938.7 CDJ68422.1 - 0.023 14.5 15.6 0.034 13.9 15.6 1.2 1 0 0 1 1 1 0 M domain of GW182 DUF4746 PF15928.5 CDJ68422.1 - 0.03 13.8 8.8 0.041 13.3 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Spt20 PF12090.8 CDJ68422.1 - 0.035 13.7 15.4 0.046 13.3 15.4 1.2 1 0 0 1 1 1 0 Spt20 family SPX PF03105.19 CDJ68422.1 - 0.044 13.7 11.9 0.052 13.5 11.9 1.1 1 0 0 1 1 1 0 SPX domain Spem1 PF15670.5 CDJ68422.1 - 0.059 12.9 3.8 0.069 12.7 3.8 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 CheY-binding PF09078.11 CDJ68422.1 - 0.063 13.4 0.6 0.15 12.2 0.6 1.6 1 0 0 1 1 1 0 CheY binding UPF0524 PF15823.5 CDJ68422.1 - 0.11 11.9 4.8 0.15 11.4 4.8 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 Cwf_Cwc_15 PF04889.12 CDJ68422.1 - 0.11 12.2 14.9 0.16 11.7 14.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Lin-8 PF03353.15 CDJ68422.1 - 0.12 11.9 14.4 0.16 11.5 14.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Bul1_C PF04426.12 CDJ68422.1 - 0.13 11.6 5.8 0.17 11.3 5.8 1.2 1 0 0 1 1 1 0 Bul1 C terminus DUF913 PF06025.12 CDJ68422.1 - 0.16 10.9 6.1 0.18 10.7 6.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Kinesin_assoc PF16183.5 CDJ68422.1 - 0.23 11.6 5.2 0.34 11.1 5.2 1.2 1 0 0 1 1 1 0 Kinesin-associated V_ATPase_I PF01496.19 CDJ68422.1 - 0.23 9.3 7.5 0.27 9.1 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dehydrin PF00257.19 CDJ68422.1 - 0.32 11.6 12.0 0.19 12.3 10.1 1.6 1 1 0 1 1 1 0 Dehydrin TERB2 PF15101.6 CDJ68422.1 - 0.32 11.0 9.6 0.45 10.5 9.6 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Uds1 PF15456.6 CDJ68422.1 - 0.34 11.1 13.1 0.52 10.5 13.1 1.2 1 0 0 1 1 1 0 Up-regulated During Septation RP-C_C PF11800.8 CDJ68422.1 - 0.4 10.8 11.1 0.66 10.0 11.1 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region RR_TM4-6 PF06459.12 CDJ68422.1 - 0.65 9.8 11.1 0.81 9.5 11.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DNA_pol_phi PF04931.13 CDJ68422.1 - 0.71 7.9 16.1 0.59 8.2 15.1 1.3 1 1 0 1 1 1 0 DNA polymerase phi UPF0697 PF15117.6 CDJ68422.1 - 0.71 10.0 3.9 1.8 8.7 3.9 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 FAM60A PF15396.6 CDJ68422.1 - 0.81 9.7 8.1 1 9.3 8.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Vfa1 PF08432.10 CDJ68422.1 - 1 9.6 14.6 1.4 9.2 14.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Plasmodium_Vir PF05795.11 CDJ68422.1 - 1.1 8.7 10.4 1.4 8.3 10.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SID-1_RNA_chan PF13965.6 CDJ68422.1 - 1.2 7.5 2.6 1.2 7.4 2.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4407 PF14362.6 CDJ68422.1 - 1.7 8.0 7.1 1.8 7.8 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.17 CDJ68422.1 - 1.9 8.6 14.8 3 7.9 14.8 1.3 1 1 0 1 1 1 0 DDHD domain SLC12 PF03522.15 CDJ68422.1 - 2.7 6.9 10.1 3.2 6.7 10.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ68422.1 - 2.7 8.0 6.4 3.5 7.6 6.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ68422.1 - 2.8 7.7 8.4 3.7 7.3 8.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DHHW PF14286.6 CDJ68422.1 - 3.1 7.0 6.4 3.7 6.8 6.4 1.1 1 0 0 1 1 1 0 DHHW protein NPR3 PF03666.13 CDJ68422.1 - 3.4 6.4 11.8 4 6.1 11.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ALMT PF11744.8 CDJ68422.1 - 3.4 6.4 6.9 3.9 6.2 6.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 CDJ68422.1 - 3.7 6.7 6.0 4.3 6.5 6.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PPL5 PF18168.1 CDJ68422.1 - 3.8 6.7 8.9 4.8 6.4 8.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 IPP-2 PF04979.14 CDJ68422.1 - 4.1 8.1 17.0 9.5 7.0 17.0 1.6 1 1 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) Sec62 PF03839.16 CDJ68422.1 - 5.6 6.4 7.3 7.2 6.0 7.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 SAPS PF04499.15 CDJ68422.1 - 6 5.5 12.3 19 3.9 11.3 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein YabA PF06156.13 CDJ68422.1 - 6.7 7.4 9.3 75 4.0 9.3 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Ndc1_Nup PF09531.10 CDJ68422.1 - 7 5.2 7.3 7.2 5.2 7.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Membralin PF09746.9 CDJ68422.1 - 7.5 5.5 5.6 9.2 5.2 5.6 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF1980 PF09323.10 CDJ68422.1 - 7.6 6.4 5.8 13 5.6 5.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Hid1 PF12722.7 CDJ68422.1 - 8 4.5 12.7 9 4.3 12.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SUIM_assoc PF16619.5 CDJ68423.1 - 0.027 14.5 2.0 0.027 14.5 2.0 5.6 5 1 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Coilin_N PF15862.5 CDJ68423.1 - 4 7.2 13.3 4.6 7.1 7.1 3.0 2 0 0 2 2 2 0 Coilin N-terminus Baculo_PP31 PF05311.11 CDJ68423.1 - 8.7 5.7 13.0 0.27 10.7 5.7 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) CCSAP PF15748.5 CDJ68425.1 - 0.013 15.7 20.5 0.5 10.5 13.2 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF3446 PF11928.8 CDJ68425.1 - 0.015 15.6 5.3 0.015 15.6 5.3 3.0 2 1 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ68425.1 - 0.016 14.9 2.5 0.016 14.9 2.5 2.8 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Caldesmon PF02029.15 CDJ68425.1 - 1.6 7.4 15.8 1.8 7.3 0.4 2.1 2 0 0 2 2 2 0 Caldesmon ATG16 PF08614.11 CDJ68425.1 - 1.7 8.8 23.8 1.4 9.1 2.2 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ATP-synt_ab PF00006.25 CDJ68426.1 - 3.4e-64 216.4 0.0 4.7e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDJ68426.1 - 3.3e-06 27.5 0.5 0.11 13.0 0.1 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, beta-barrel domain DUF4131 PF13567.6 CDJ68426.1 - 6.8 6.3 10.9 0.68 9.6 4.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Alkyl_sulf_dimr PF14863.6 CDJ68427.1 - 0.27 11.7 2.2 0.56 10.7 2.2 1.5 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation DUF1645 PF07816.11 CDJ68427.1 - 4.9 7.7 9.2 0.27 11.8 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ68428.1 - 0.00061 19.5 22.0 0.021 14.5 7.8 2.2 2 0 0 2 2 2 2 Spt20 family SUIM_assoc PF16619.5 CDJ68428.1 - 0.018 15.1 5.0 0.018 15.1 5.0 3.0 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Velvet PF11754.8 CDJ68428.1 - 0.066 13.1 9.5 0.7 9.8 2.5 2.3 2 0 0 2 2 2 0 Velvet factor SR-25 PF10500.9 CDJ68428.1 - 0.084 12.5 10.4 0.038 13.6 2.3 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.16 CDJ68428.1 - 0.17 11.9 5.1 1.6 8.7 1.9 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RAB3GAP2_N PF14655.6 CDJ68428.1 - 4.4 6.5 11.5 2.9 7.1 3.5 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2981 PF11200.8 CDJ68429.1 - 0.92 9.2 6.7 1.7 8.3 6.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) CemA PF03040.14 CDJ68429.1 - 1.6 8.6 3.7 2.7 7.9 3.7 1.4 1 0 0 1 1 1 0 CemA family MMR1 PF08505.10 CDJ68429.1 - 2 8.6 28.1 0.039 14.3 16.0 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein CSG2 PF16965.5 CDJ68429.1 - 2.2 7.1 8.2 3.1 6.7 8.2 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator RT_RNaseH_2 PF17919.1 CDJ68430.1 - 3.7e-25 87.9 0.0 7.2e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ68430.1 - 4.9e-25 87.8 0.0 1.2e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ68430.1 - 5.7e-16 58.8 0.1 5.7e-15 55.5 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ68430.1 - 6.1e-16 58.3 1.5 1.8e-15 56.8 1.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 CDJ68430.1 - 4.6e-13 48.9 0.0 8.8e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CDJ68430.1 - 5.4e-05 23.3 0.4 0.00012 22.2 0.4 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDJ68430.1 - 0.041 13.7 0.3 0.43 10.4 0.2 2.4 2 0 0 2 2 2 0 Integrase core domain rve PF00665.26 CDJ68431.1 - 2.6e-15 56.7 0.1 6.9e-14 52.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 CDJ68431.1 - 7.2e-13 48.7 0.2 1.4e-12 47.8 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ68431.1 - 0.00063 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase YsaB PF13983.6 CDJ68431.1 - 0.016 15.5 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 YsaB-like lipoprotein rve_3 PF13683.6 CDJ68431.1 - 0.017 14.9 0.2 0.045 13.5 0.2 1.7 1 0 0 1 1 1 0 Integrase core domain Chromo PF00385.24 CDJ68431.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain R3H-assoc PF13902.6 CDJ68435.1 - 0.082 13.3 0.0 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 R3H-associated N-terminal domain LRR_8 PF13855.6 CDJ68436.1 - 6.3e-05 22.7 5.0 0.00013 21.7 3.8 2.0 2 0 0 2 2 2 1 Leucine rich repeat FHIPEP PF00771.20 CDJ68436.1 - 9.3e-05 21.1 1.9 0.00011 20.8 1.9 1.0 1 0 0 1 1 1 1 FHIPEP family RskA PF10099.9 CDJ68436.1 - 0.00018 21.8 14.3 0.00031 21.1 14.3 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ68436.1 - 0.0005 20.2 18.2 0.00062 19.9 18.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ68436.1 - 0.00051 19.1 9.9 0.00051 19.1 9.9 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ68436.1 - 0.0013 18.4 9.2 0.0071 16.0 5.1 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF3371 PF11851.8 CDJ68436.1 - 0.0035 18.4 0.9 0.0035 18.4 0.9 2.3 2 0 0 2 2 1 1 Domain of unknown function (DUF3371) LRR_4 PF12799.7 CDJ68436.1 - 0.014 15.8 2.3 0.046 14.2 0.2 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ68436.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat SprA-related PF12118.8 CDJ68436.1 - 0.02 14.0 17.6 0.032 13.4 17.6 1.2 1 0 0 1 1 1 0 SprA-related family PH_4 PF15404.6 CDJ68436.1 - 0.062 13.1 1.1 0.11 12.3 1.1 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain BRF1 PF07741.13 CDJ68436.1 - 0.072 13.4 0.6 0.072 13.4 0.6 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain PAT1 PF09770.9 CDJ68436.1 - 0.14 10.4 13.9 0.18 10.1 13.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 CDJ68436.1 - 0.14 11.1 4.4 0.16 10.9 4.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BAF1_ABF1 PF04684.13 CDJ68436.1 - 0.15 11.1 4.0 0.2 10.7 4.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Orf78 PF06024.12 CDJ68436.1 - 0.17 12.2 3.0 0.33 11.3 3.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) CCSAP PF15748.5 CDJ68436.1 - 0.26 11.4 11.6 0.37 10.9 11.6 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated EIIBC-GUT_N PF03612.14 CDJ68436.1 - 0.31 10.8 2.9 0.54 10.0 2.9 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 CDJ68436.1 - 0.62 8.8 8.5 0.84 8.3 8.5 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ68436.1 - 0.64 8.6 7.1 0.74 8.4 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CbtA PF09490.10 CDJ68436.1 - 0.85 9.3 11.0 1.2 8.8 11.0 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) TERB2 PF15101.6 CDJ68436.1 - 8.5 6.4 10.4 0.53 10.3 5.0 1.7 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Ndc1_Nup PF09531.10 CDJ68437.1 - 0.46 9.1 31.0 0.55 8.9 31.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LAP1C PF05609.12 CDJ68437.1 - 0.93 8.5 30.8 1 8.4 30.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CAML PF14963.6 CDJ68437.1 - 1.3 9.1 13.9 2.3 8.3 13.9 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Trypan_PARP PF05887.11 CDJ68437.1 - 1.7 8.7 5.7 2.9 7.9 5.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 CDJ68438.1 - 6.7e-22 78.1 1.4 3.2e-07 30.0 0.0 5.0 5 1 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ68438.1 - 6.5e-05 22.3 0.0 0.0079 15.5 0.0 3.2 3 1 0 3 3 3 1 Protein tyrosine kinase Spt20 PF12090.8 CDJ68438.1 - 0.0016 18.1 84.3 0.011 15.4 0.8 5.4 5 0 0 5 5 5 4 Spt20 family PRCC PF10253.9 CDJ68438.1 - 0.0025 18.6 6.2 0.0025 18.6 6.2 4.9 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting SUIM_assoc PF16619.5 CDJ68439.1 - 0.00049 20.1 0.6 0.00097 19.2 0.6 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 EF-hand_7 PF13499.6 CDJ68439.1 - 0.099 13.1 0.0 20 5.7 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair UPF0492 PF15744.5 CDJ68439.1 - 0.1 11.8 1.6 0.15 11.3 1.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Spt20 PF12090.8 CDJ68439.1 - 1 9.0 9.8 1.7 8.2 9.8 1.3 1 0 0 1 1 1 0 Spt20 family Sporozoite_P67 PF05642.11 CDJ68440.1 - 0.0031 15.7 0.4 0.0036 15.5 0.4 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen GREB1 PF15782.5 CDJ68440.1 - 2.3 5.2 4.1 2.2 5.3 4.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 CDJ68440.1 - 4.8 7.2 5.4 7.3 6.6 5.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Coilin_N PF15862.5 CDJ68440.1 - 7.4 6.4 7.2 12 5.7 7.2 1.3 1 0 0 1 1 1 0 Coilin N-terminus Hamartin PF04388.12 CDJ68441.1 - 8 5.0 30.7 12 4.4 30.7 1.2 1 0 0 1 1 1 0 Hamartin protein LMP PF04778.12 CDJ68442.1 - 0.034 14.1 3.3 0.048 13.6 3.3 1.2 1 0 0 1 1 1 0 LMP repeated region tRNA_lig_CPD PF08302.11 CDJ68442.1 - 0.17 11.3 1.7 0.22 11.0 1.7 1.1 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain ThiS PF02597.20 CDJ68442.1 - 3.9 8.2 5.8 12 6.7 0.4 2.7 1 1 2 3 3 3 0 ThiS family Apt1 PF10351.9 CDJ68443.1 - 0.35 9.7 4.0 0.28 10.0 4.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ68443.1 - 0.56 8.7 5.0 0.5 8.9 5.0 1.2 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 CDJ68443.1 - 2.6 7.9 9.2 3 7.7 9.2 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosomal_60s PF00428.19 CDJ68443.1 - 2.9 8.6 14.3 0.2 12.3 6.3 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4614 PF15391.6 CDJ68443.1 - 7 6.6 13.8 9.1 6.2 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF1645 PF07816.11 CDJ68444.1 - 4.9e-05 24.0 7.0 5.7e-05 23.8 7.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) DUF4667 PF15700.5 CDJ68444.1 - 0.00049 20.3 6.8 0.00053 20.2 6.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) Presenilin PF01080.17 CDJ68444.1 - 0.00084 18.2 6.4 0.001 17.9 6.4 1.0 1 0 0 1 1 1 1 Presenilin PAP_PilO PF06864.12 CDJ68444.1 - 0.003 16.4 6.1 0.0039 16.1 6.1 1.1 1 0 0 1 1 1 1 Pilin accessory protein (PilO) TFIIA PF03153.13 CDJ68444.1 - 0.0031 17.6 17.0 0.0036 17.4 17.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ68444.1 - 0.0042 16.7 19.1 0.006 16.2 19.1 1.3 1 0 0 1 1 1 1 Spt20 family SARAF PF06682.12 CDJ68444.1 - 0.0081 15.9 8.0 0.01 15.5 8.0 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis eIF-3_zeta PF05091.12 CDJ68444.1 - 0.016 14.2 2.4 0.016 14.2 2.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAA_hydro_N_2 PF18288.1 CDJ68444.1 - 0.021 15.2 0.9 0.036 14.5 0.9 1.3 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 MAP65_ASE1 PF03999.12 CDJ68444.1 - 0.025 13.3 11.6 0.033 12.9 11.6 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MPM1 PF17234.2 CDJ68444.1 - 0.027 14.7 9.4 0.036 14.3 9.4 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Macoilin PF09726.9 CDJ68444.1 - 0.067 11.7 10.9 0.084 11.4 10.9 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CDJ68444.1 - 0.11 9.6 12.1 0.13 9.4 12.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sec1 PF00995.23 CDJ68444.1 - 0.16 11.1 2.1 0.19 11.0 2.1 1.2 1 0 0 1 1 1 0 Sec1 family PepSY_TM PF03929.16 CDJ68444.1 - 0.24 11.0 3.5 0.29 10.8 3.5 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Gti1_Pac2 PF09729.9 CDJ68444.1 - 0.25 11.4 4.5 0.37 10.9 4.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family V_ATPase_I PF01496.19 CDJ68444.1 - 0.28 9.1 2.9 0.32 8.8 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 CDJ68444.1 - 0.3 10.4 5.7 0.36 10.1 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SLC12 PF03522.15 CDJ68444.1 - 0.4 9.6 4.9 0.48 9.4 4.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PI3K_1B_p101 PF10486.9 CDJ68444.1 - 0.4 8.4 6.7 0.51 8.1 6.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Apt1 PF10351.9 CDJ68444.1 - 0.45 9.3 10.7 0.55 9.0 10.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SRP-alpha_N PF04086.13 CDJ68444.1 - 0.55 10.1 9.7 0.64 9.9 9.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Roughex PF06020.11 CDJ68444.1 - 0.6 9.1 11.9 0.76 8.8 11.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TRAPPC9-Trs120 PF08626.11 CDJ68444.1 - 0.69 7.2 6.9 0.83 6.9 6.9 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF4834 PF16118.5 CDJ68444.1 - 0.72 10.9 10.1 0.073 14.0 4.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CCDC24 PF15669.5 CDJ68444.1 - 0.93 9.3 10.8 1.3 8.9 10.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family TAF4 PF05236.14 CDJ68444.1 - 1 9.1 11.7 1.3 8.7 11.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Lin-8 PF03353.15 CDJ68444.1 - 1.1 8.8 17.2 1.4 8.4 17.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NST1 PF13945.6 CDJ68444.1 - 1.4 9.0 14.5 2 8.5 14.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Miga PF10265.9 CDJ68444.1 - 1.5 7.7 7.6 1.8 7.4 7.6 1.1 1 0 0 1 1 1 0 Mitoguardin Peptidase_S64 PF08192.11 CDJ68444.1 - 1.6 7.1 12.6 2 6.8 12.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 CLN3 PF02487.17 CDJ68444.1 - 2 7.3 3.1 2.4 7.1 3.1 1.1 1 0 0 1 1 1 0 CLN3 protein API5 PF05918.11 CDJ68444.1 - 2.2 7.0 9.0 2.7 6.7 9.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SPX PF03105.19 CDJ68444.1 - 2.8 7.8 18.9 3.4 7.5 18.9 1.1 1 0 0 1 1 1 0 SPX domain Hid1 PF12722.7 CDJ68444.1 - 3.3 5.7 8.9 3.8 5.5 8.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.6 CDJ68444.1 - 3.5 6.4 10.1 4.3 6.1 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ALMT PF11744.8 CDJ68444.1 - 3.7 6.3 6.9 4.7 5.9 6.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM220 PF15487.6 CDJ68444.1 - 4.7 6.8 12.9 6.2 6.4 12.9 1.1 1 0 0 1 1 1 0 FAM220 family TMEM208_SND2 PF05620.11 CDJ68444.1 - 6.4 6.5 6.3 10 5.8 6.3 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 RR_TM4-6 PF06459.12 CDJ68444.1 - 6.7 6.5 8.7 8.5 6.1 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Menin PF05053.13 CDJ68444.1 - 6.9 4.9 10.6 9.2 4.5 10.6 1.1 1 0 0 1 1 1 0 Menin Herpes_capsid PF06112.11 CDJ68444.1 - 7.3 6.6 21.1 9.6 6.2 21.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Peroxin-3 PF04882.12 CDJ68444.1 - 8 5.3 14.8 9.8 5.0 14.8 1.1 1 0 0 1 1 1 0 Peroxin-3 DNA_pol_E_B PF04042.16 CDJ68445.1 - 1.9e-24 86.2 0.0 4.7e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CDJ68445.1 - 5.9e-07 29.6 0.0 1.7e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain SR-25 PF10500.9 CDJ68445.1 - 0.0097 15.5 13.9 0.015 14.9 13.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Smg4_UPF3 PF03467.15 CDJ68445.1 - 0.011 15.8 0.0 0.011 15.8 0.0 2.4 2 0 0 2 2 2 0 Smg-4/UPF3 family Presenilin PF01080.17 CDJ68445.1 - 0.02 13.7 4.4 0.027 13.2 4.4 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ68445.1 - 0.028 13.2 5.1 0.035 12.8 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAD-SLDH PF12318.8 CDJ68445.1 - 0.029 14.4 1.9 0.029 14.4 1.9 4.1 4 0 0 4 4 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Neur_chan_memb PF02932.16 CDJ68445.1 - 0.049 13.7 4.9 0.088 12.9 4.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ68445.1 - 0.14 12.1 10.5 0.24 11.4 10.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CCSAP PF15748.5 CDJ68445.1 - 0.51 10.5 17.2 0.91 9.6 17.2 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Spt20 PF12090.8 CDJ68445.1 - 2.8 7.5 26.3 4.7 6.8 26.3 1.3 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 CDJ68445.1 - 3 6.0 16.0 4.2 5.5 16.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 USP8_interact PF08941.10 CDJ68445.1 - 3.2 7.5 6.9 5 6.9 6.9 1.2 1 0 0 1 1 1 0 USP8 interacting CENP-I PF07778.11 CDJ68445.1 - 5.9 5.5 6.3 8 5.0 6.3 1.1 1 0 0 1 1 1 0 Mis6 eIF-3_zeta PF05091.12 CDJ68445.1 - 8.9 5.2 13.3 13 4.6 13.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DnaGprimase_HBD PF16730.5 CDJ68446.1 - 0.012 15.6 12.2 0.039 14.0 7.0 2.0 1 1 1 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain GerPC PF10737.9 CDJ68446.1 - 0.018 15.1 10.0 0.024 14.7 10.0 1.1 1 0 0 1 1 1 0 Spore germination protein GerPC RIFIN PF02009.16 CDJ68446.1 - 0.031 14.2 5.3 0.037 13.9 5.3 1.1 1 0 0 1 1 1 0 Rifin DUF445 PF04286.12 CDJ68446.1 - 0.042 13.7 6.2 0.047 13.5 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HI0933_like PF03486.14 CDJ68446.1 - 0.061 12.0 8.4 0.075 11.7 8.4 1.2 1 0 0 1 1 1 0 HI0933-like protein FAM199X PF15814.5 CDJ68446.1 - 0.11 11.6 5.3 0.13 11.3 5.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X DUF2232 PF09991.9 CDJ68446.1 - 0.37 9.9 9.1 0.67 9.1 9.1 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF2497 PF10691.9 CDJ68446.1 - 0.48 10.9 7.4 0.54 10.7 6.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2497) Activator_LAG-3 PF11498.8 CDJ68446.1 - 0.57 9.1 37.5 0.69 8.8 37.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4403 PF14356.6 CDJ68446.1 - 0.64 8.6 8.7 0.46 9.1 7.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4403) DUF3533 PF12051.8 CDJ68446.1 - 2.4 7.0 11.7 3 6.7 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Zea_mays_MuDR PF05928.11 CDJ68446.1 - 2.6 7.6 4.8 3 7.4 4.8 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Peptidase_S15 PF02129.18 CDJ68446.1 - 3.3 7.2 10.3 3.8 7.0 10.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) TFIIA PF03153.13 CDJ68446.1 - 4.3 7.2 31.5 5.5 6.9 31.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fusion_gly PF00523.18 CDJ68446.1 - 5.3 5.2 15.7 6.2 4.9 15.7 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 Erythro_esteras PF05139.14 CDJ68446.1 - 5.9 6.6 11.5 7.3 6.3 11.5 1.2 1 0 0 1 1 1 0 Erythromycin esterase DUF1631 PF07793.11 CDJ68446.1 - 6.7 5.0 33.5 7.9 4.8 33.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF4667 PF15700.5 CDJ68447.1 - 0.013 15.7 0.0 0.013 15.7 0.0 4.3 3 2 0 3 3 3 0 Domain of unknown function (DUF4667) PseudoU_synth_2 PF00849.22 CDJ68447.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA pseudouridylate synthase K_channel_TID PF07941.11 CDJ68447.1 - 0.016 15.6 1.0 0.016 15.6 1.0 5.6 3 2 2 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain SR-25 PF10500.9 CDJ68448.1 - 0.0043 16.7 10.8 0.0047 16.6 10.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ68448.1 - 1.3 9.8 11.3 1.8 9.3 11.3 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF755 PF05501.11 CDJ68448.1 - 3.7 7.8 15.9 4.7 7.5 15.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Syntaphilin PF15290.6 CDJ68448.1 - 8.2 6.0 9.3 9.6 5.8 9.3 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Otopetrin PF03189.13 CDJ68450.1 - 1.8 7.3 6.4 5 5.8 0.1 2.9 2 1 1 3 3 3 0 Otopetrin Draxin PF15550.6 CDJ68450.1 - 5.6 6.7 32.1 3 7.6 15.1 2.6 2 0 0 2 2 2 0 Draxin AAA_23 PF13476.6 CDJ68451.1 - 0.011 16.2 18.6 0.017 15.6 18.6 1.3 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 CDJ68451.1 - 0.05 11.5 19.7 0.088 10.7 19.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2828 PF11443.8 CDJ68451.1 - 0.28 9.2 17.6 0.44 8.6 17.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Connexin PF00029.19 CDJ68451.1 - 0.52 10.0 14.5 0.25 11.1 11.8 1.7 2 0 0 2 2 2 0 Connexin DUF2126 PF09899.9 CDJ68451.1 - 1.1 7.2 10.4 1.4 6.9 10.4 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CBP_BcsG PF11658.8 CDJ68451.1 - 1.9 6.8 15.2 2.8 6.2 15.2 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Serinc PF03348.15 CDJ68451.1 - 2.2 7.1 14.8 0.033 13.1 7.0 1.7 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF3807 PF12720.7 CDJ68451.1 - 2.5 8.4 33.9 0.92 9.8 23.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Folate_carrier PF01770.18 CDJ68451.1 - 2.5 6.8 10.5 6 5.5 10.5 1.6 1 0 0 1 1 1 0 Reduced folate carrier SART-1 PF03343.13 CDJ68451.1 - 2.6 6.5 27.7 4.5 5.7 27.7 1.3 1 0 0 1 1 1 0 SART-1 family Scs3p PF10261.9 CDJ68451.1 - 3.3 7.2 5.3 6.2 6.2 5.3 1.5 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM RR_TM4-6 PF06459.12 CDJ68451.1 - 5.3 6.8 22.5 0.3 10.9 16.7 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FYDLN_acid PF09538.10 CDJ68451.1 - 7.9 7.2 11.7 5.3 7.8 8.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF719 PF05334.13 CDJ68452.1 - 0.072 13.3 3.4 0.79 9.9 3.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF2722 PF10846.8 CDJ68452.1 - 0.28 10.1 5.3 0.36 9.7 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Lsr2 PF11774.8 CDJ68452.1 - 0.38 10.9 4.6 0.64 10.2 4.6 1.3 1 0 0 1 1 1 0 Lsr2 Spt20 PF12090.8 CDJ68452.1 - 0.45 10.1 10.3 0.61 9.7 10.3 1.1 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ68452.1 - 2.7 6.8 15.5 4.7 5.9 15.5 1.3 1 0 0 1 1 1 0 Androgen receptor Med3 PF11593.8 CDJ68452.1 - 7.6 5.6 9.8 10 5.2 9.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RNA_pol_Rpb1_5 PF04998.17 CDJ68453.1 - 4e-46 157.6 0.0 8.6e-46 156.5 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RSRP PF17069.5 CDJ68453.1 - 0.055 13.0 16.8 0.099 12.2 16.8 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Apt1 PF10351.9 CDJ68453.1 - 2 7.2 4.6 0.97 8.2 1.4 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF2722 PF10846.8 CDJ68453.1 - 4.8 6.0 14.8 0.037 13.0 5.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ68453.1 - 6 7.9 7.7 0.44 11.5 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) UPF0565 PF10561.9 CDJ68454.1 - 9.8e-06 25.0 5.5 1.2e-05 24.7 5.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 Trp_oprn_chp PF09534.10 CDJ68454.1 - 0.0018 18.1 9.4 0.0024 17.7 9.4 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sin_N PF04801.13 CDJ68454.1 - 0.0048 16.2 15.7 0.0057 15.9 15.7 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region Peptidase_S46 PF10459.9 CDJ68454.1 - 0.019 13.7 11.2 0.022 13.4 11.2 1.0 1 0 0 1 1 1 0 Peptidase S46 CCDC53 PF10152.9 CDJ68454.1 - 0.021 15.2 8.2 0.028 14.9 8.2 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3818 PF12825.7 CDJ68454.1 - 0.052 12.6 4.2 0.059 12.4 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) GAGA_bind PF06217.12 CDJ68454.1 - 0.071 13.4 8.1 0.081 13.2 8.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIA PF03153.13 CDJ68454.1 - 0.11 12.5 32.4 0.12 12.3 32.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 CDJ68454.1 - 0.21 10.4 12.7 0.24 10.2 12.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF853 PF05872.12 CDJ68454.1 - 0.26 9.8 10.3 0.32 9.5 10.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Activator_LAG-3 PF11498.8 CDJ68454.1 - 0.32 9.9 33.2 0.37 9.7 33.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CCSAP PF15748.5 CDJ68454.1 - 0.46 10.6 14.4 0.6 10.2 14.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated IHABP4_N PF16174.5 CDJ68454.1 - 0.71 10.5 14.3 1 10.0 14.3 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4813 PF16072.5 CDJ68454.1 - 0.85 9.2 13.8 1.1 8.9 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF4366 PF14283.6 CDJ68454.1 - 0.91 9.6 5.6 0.43 10.6 3.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) RR_TM4-6 PF06459.12 CDJ68454.1 - 1.2 8.9 8.4 1.4 8.7 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 CDJ68454.1 - 1.7 6.8 20.5 1.8 6.7 20.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S15 PF02129.18 CDJ68454.1 - 2.4 7.7 10.9 3.1 7.3 10.9 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Band_3_cyto PF07565.13 CDJ68454.1 - 2.5 7.8 9.9 3.6 7.3 9.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4407 PF14362.6 CDJ68454.1 - 3.6 6.8 19.7 4.6 6.5 19.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Erythro_esteras PF05139.14 CDJ68454.1 - 3.8 7.2 12.2 4.6 6.9 12.2 1.0 1 0 0 1 1 1 0 Erythromycin esterase SLC12 PF03522.15 CDJ68454.1 - 3.9 6.4 10.2 4.5 6.2 10.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF572 PF04502.13 CDJ68454.1 - 4.5 6.8 12.5 5.2 6.6 12.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) RIFIN PF02009.16 CDJ68454.1 - 5.3 6.8 16.6 7.1 6.4 16.6 1.1 1 0 0 1 1 1 0 Rifin XRN_M PF17846.1 CDJ68454.1 - 5.9 5.7 6.9 7 5.5 6.9 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Ashwin PF15323.6 CDJ68454.1 - 8.1 6.4 15.3 13 5.7 15.3 1.4 1 1 0 1 1 1 0 Developmental protein SAP PF02037.27 CDJ68455.1 - 1.2e-14 53.6 0.2 2.9e-14 52.4 0.1 1.7 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 CDJ68455.1 - 3.4e-07 30.0 11.9 0.00034 20.4 1.3 3.4 1 1 2 3 3 3 3 Tho1/MOS11 C-terminal domain HeH PF12949.7 CDJ68455.1 - 0.0013 18.4 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain FANC_SAP PF18081.1 CDJ68455.1 - 0.051 13.7 2.6 0.051 13.7 2.6 2.2 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Herpes_TAF50 PF03326.13 CDJ68455.1 - 0.12 11.0 9.2 0.14 10.8 9.2 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) CDC27 PF09507.10 CDJ68455.1 - 1.3 8.3 12.4 1.6 8.0 12.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4179 PF13786.6 CDJ68455.1 - 6.6 7.3 7.8 5.9e+02 1.0 7.8 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) FSA_C PF10479.9 CDJ68455.1 - 9.9 4.2 6.8 11 3.9 6.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Adaptin_N PF01602.20 CDJ68456.1 - 1.9e-54 185.1 0.2 3.8e-31 108.3 0.3 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 CDJ68456.1 - 9.6e-08 32.2 0.2 2.8e-07 30.7 0.2 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 BLOC1S3 PF15753.5 CDJ68456.1 - 0.0044 17.2 3.7 0.0044 17.2 3.7 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 Pex14_N PF04695.13 CDJ68456.1 - 0.012 16.2 4.2 0.012 16.2 4.2 3.3 3 1 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SUIM_assoc PF16619.5 CDJ68456.1 - 0.084 13.0 0.0 0.084 13.0 0.0 5.2 6 1 0 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 HEAT PF02985.22 CDJ68456.1 - 2.1 8.8 19.6 6 7.4 0.1 6.2 6 0 0 6 6 6 0 HEAT repeat TFIIA PF03153.13 CDJ68456.1 - 8 6.3 42.9 3.4 7.6 12.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit XPG_I PF00867.18 CDJ68457.1 - 1.5e-28 98.9 0.3 3.9e-28 97.6 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 CDJ68457.1 - 2.6e-26 92.0 0.3 1.1e-25 90.0 0.0 2.2 2 1 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 CDJ68457.1 - 0.00015 22.3 0.0 0.00054 20.5 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF4834 PF16118.5 CDJ68457.1 - 0.14 13.2 3.6 0.39 11.7 3.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ68457.1 - 0.16 11.6 12.5 0.24 11.0 12.5 1.2 1 0 0 1 1 1 0 Spt20 family KCNQ2_u3 PF16642.5 CDJ68457.1 - 0.22 12.5 5.3 0.2 12.7 1.5 2.4 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 TFIIA PF03153.13 CDJ68457.1 - 2.3 8.1 12.8 0.88 9.5 10.2 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hep_59 PF07052.11 CDJ68457.1 - 2.6 8.8 8.8 6.9 7.5 4.8 2.4 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 DUF3043 PF11241.8 CDJ68457.1 - 2.8 8.0 11.7 1.4 9.0 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Activator_LAG-3 PF11498.8 CDJ68458.1 - 0.0046 16.0 48.5 0.0046 16.0 48.5 5.2 5 0 0 5 5 5 1 Transcriptional activator LAG-3 RAP1 PF07218.11 CDJ68458.1 - 0.18 10.1 6.5 0.41 8.9 6.5 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IQ PF00612.27 CDJ68459.1 - 1.7e-05 24.2 41.5 0.0064 16.2 3.2 5.3 4 0 0 4 4 4 4 IQ calmodulin-binding motif Collagen PF01391.18 CDJ68459.1 - 0.0087 15.8 5.2 0.0087 15.8 5.2 1.6 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) MCM PF00493.23 CDJ68462.1 - 1.4e-54 184.5 0.2 2.5e-54 183.7 0.2 1.4 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 CDJ68462.1 - 0.00025 20.5 0.1 0.0024 17.3 0.1 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CDJ68462.1 - 0.0032 17.2 0.2 0.027 14.2 0.2 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 CDJ68462.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Peptidase_M20 PF01546.28 CDJ68462.1 - 0.19 11.4 1.8 0.54 9.9 1.8 2.0 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 DUF3446 PF11928.8 CDJ68463.1 - 0.0057 16.9 4.5 0.0057 16.9 4.5 2.4 2 0 0 2 2 2 1 Early growth response N-terminal domain CPL PF08144.11 CDJ68463.1 - 0.098 13.0 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 CPL (NUC119) domain SelB-wing_2 PF09106.11 CDJ68463.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.6 4 0 0 4 4 4 0 Elongation factor SelB, winged helix LexA_DNA_bind PF01726.16 CDJ68463.1 - 0.72 9.7 3.3 0.78 9.6 0.1 2.7 3 0 0 3 3 3 0 LexA DNA binding domain SR-25 PF10500.9 CDJ68463.1 - 1.7 8.2 7.6 2.7 7.5 7.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tsg PF04668.12 CDJ68464.1 - 0.012 16.3 2.4 0.017 15.8 0.7 1.9 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region Suf PF05843.14 CDJ68464.1 - 0.37 10.7 10.4 0.93 9.4 6.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Mak16 PF04874.14 CDJ68464.1 - 0.86 10.2 6.4 0.65 10.6 3.5 2.0 2 0 0 2 2 2 0 Mak16 protein C-terminal region Nup192 PF11894.8 CDJ68464.1 - 1.1 6.2 11.5 0.047 10.8 5.6 1.5 2 0 0 2 2 2 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 TFIIA PF03153.13 CDJ68464.1 - 5.1 7.0 36.3 2.7 7.9 26.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.3 CDJ68464.1 - 5.9 7.1 7.9 12 6.1 5.2 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 CDJ68464.1 - 7.4 5.2 5.7 1.2 7.9 1.7 1.6 2 0 0 2 2 2 0 Presenilin RRM_1 PF00076.22 CDJ68465.1 - 1.8e-05 24.4 0.0 3.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CDJ68465.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 RL domain RRM_7 PF16367.5 CDJ68465.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif DUF1744 PF08490.12 CDJ68467.1 - 1.2e-15 57.0 2.3 3.8e-15 55.4 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) Macoilin PF09726.9 CDJ68467.1 - 0.0023 16.6 13.8 0.0023 16.6 13.8 4.8 4 1 0 4 4 4 3 Macoilin family BUD22 PF09073.10 CDJ68467.1 - 8.3 5.6 53.3 0.73 9.1 11.5 4.3 4 0 0 4 4 4 0 BUD22 Ribosomal_60s PF00428.19 CDJ68468.1 - 0.0079 16.8 11.8 0.0079 16.8 11.8 2.3 3 0 0 3 3 3 1 60s Acidic ribosomal protein CNOT1_CAF1_bind PF16415.5 CDJ68469.1 - 3.6e-61 206.4 8.5 1.3e-47 162.0 0.3 2.5 3 0 0 3 3 3 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 CDJ68469.1 - 3.7e-12 45.8 0.0 3.7e-12 45.8 0.0 4.7 4 1 1 5 5 5 1 CCR4-NOT transcription complex subunit 1 TTP binding domain Pex14_N PF04695.13 CDJ68469.1 - 0.002 18.8 10.9 0.002 18.8 10.9 6.2 4 1 1 5 5 5 3 Peroxisomal membrane anchor protein (Pex14p) conserved region Arv1 PF04161.13 CDJ68470.1 - 5.4e-34 118.2 7.4 2.7e-31 109.4 1.2 3.4 3 1 0 3 3 3 2 Arv1-like family DUF2722 PF10846.8 CDJ68470.1 - 0.00025 20.2 2.0 0.00025 20.2 2.0 4.0 3 1 0 3 3 3 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ68470.1 - 0.0015 18.2 5.7 0.0015 18.2 5.7 3.7 3 1 0 3 3 3 2 Spt20 family BatD PF13584.6 CDJ68470.1 - 0.003 16.4 2.5 0.0032 16.4 0.0 2.4 3 1 0 3 3 3 1 Oxygen tolerance DUF2052 PF09747.9 CDJ68470.1 - 0.004 17.3 1.5 0.004 17.3 1.5 3.0 3 0 0 3 3 3 2 Coiled-coil domain containing protein (DUF2052) DUF2681 PF10883.8 CDJ68470.1 - 0.015 15.7 1.4 0.015 15.7 1.4 6.2 6 1 0 6 6 6 0 Protein of unknown function (DUF2681) EPL1 PF10513.9 CDJ68470.1 - 0.14 12.6 16.1 0.51 10.7 3.1 3.3 3 0 0 3 3 3 0 Enhancer of polycomb-like RskA PF10099.9 CDJ68470.1 - 0.73 10.1 0.0 0.73 10.1 0.0 6.4 3 2 1 4 4 4 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ68470.1 - 1.7 7.3 21.0 4.6 5.9 1.1 3.1 3 0 0 3 3 3 0 Presenilin MAM33 PF02330.16 CDJ68470.1 - 8.4 6.3 16.7 1.9 8.3 5.9 3.1 3 0 0 3 3 3 0 Mitochondrial glycoprotein Sec7_N PF12783.7 CDJ68471.1 - 2.1e-09 37.5 11.7 4.1e-09 36.5 7.9 3.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal SR-25 PF10500.9 CDJ68471.1 - 0.014 15.1 0.4 0.014 15.1 0.4 14.6 15 3 1 16 16 16 0 Nuclear RNA-splicing-associated protein SARAF PF06682.12 CDJ68471.1 - 0.015 15.0 0.4 0.015 15.0 0.4 8.7 8 1 1 9 9 9 0 SOCE-associated regulatory factor of calcium homoeostasis CSN8_PSD8_EIF3K PF10075.9 CDJ68472.1 - 1.9e-15 57.1 0.1 3.3e-15 56.3 0.1 1.4 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 CDJ68472.1 - 0.15 12.6 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 PCI domain Sdh5 PF03937.16 CDJ68473.1 - 0.012 15.6 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase SPX PF03105.19 CDJ68473.1 - 0.1 12.5 2.7 0.16 11.8 2.7 1.3 1 0 0 1 1 1 0 SPX domain ACDC PF14733.6 CDJ68476.1 - 2.2e-08 34.3 0.1 3.5e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal HEAT_EZ PF13513.6 CDJ68476.1 - 0.18 12.4 5.1 1.1 9.9 0.8 2.9 3 0 0 3 3 3 0 HEAT-like repeat SRC-1 PF08832.10 CDJ68476.1 - 0.54 11.3 8.6 1.2 10.2 0.1 3.1 3 0 0 3 3 3 0 Steroid receptor coactivator IMUP PF15761.5 CDJ68476.1 - 3.4 8.4 30.3 0.5 11.1 5.2 3.2 3 0 0 3 3 3 0 Immortalisation up-regulated protein Rrn6 PF10214.9 CDJ68476.1 - 7.4 4.9 9.8 14 4.0 9.7 1.5 1 1 1 2 2 2 0 RNA polymerase I-specific transcription-initiation factor RED_N PF07808.13 CDJ68477.1 - 6.2e-19 68.5 19.6 1.5e-18 67.2 14.9 2.6 1 1 1 2 2 2 1 RED-like protein N-terminal region TAF4 PF05236.14 CDJ68478.1 - 0.0031 17.3 1.9 0.0031 17.3 1.9 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Spt20 PF12090.8 CDJ68478.1 - 0.018 14.7 19.0 0.021 14.5 19.0 1.1 1 0 0 1 1 1 0 Spt20 family DUF1635 PF07795.11 CDJ68478.1 - 0.019 14.8 10.4 0.026 14.4 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) ThiF PF00899.21 CDJ68478.1 - 0.04 13.3 1.2 0.043 13.2 0.4 1.5 1 1 1 2 2 2 0 ThiF family Menin PF05053.13 CDJ68478.1 - 0.058 11.8 5.2 0.058 11.8 5.2 1.0 1 0 0 1 1 1 0 Menin Cwf_Cwc_15 PF04889.12 CDJ68478.1 - 0.06 13.1 5.5 0.072 12.8 5.5 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Apt1 PF10351.9 CDJ68478.1 - 0.068 12.0 11.8 0.076 11.9 11.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3295 PF11702.8 CDJ68478.1 - 0.17 11.2 17.6 0.2 11.0 17.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Lin-8 PF03353.15 CDJ68478.1 - 0.17 11.4 12.3 0.22 11.1 12.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sporozoite_P67 PF05642.11 CDJ68478.1 - 0.17 9.9 11.2 0.18 9.9 11.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Miga PF10265.9 CDJ68478.1 - 0.2 10.6 8.1 0.21 10.5 8.1 1.0 1 0 0 1 1 1 0 Mitoguardin RAP1 PF07218.11 CDJ68478.1 - 0.25 9.6 12.3 0.26 9.5 12.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Parvo_coat_N PF08398.10 CDJ68478.1 - 0.26 11.4 1.9 0.34 11.1 0.6 1.8 1 1 0 2 2 2 0 Parvovirus coat protein VP1 JHY PF15261.6 CDJ68478.1 - 0.27 11.9 7.8 0.37 11.5 7.8 1.1 1 0 0 1 1 1 0 Jhy protein DUF1645 PF07816.11 CDJ68478.1 - 0.31 11.6 17.5 0.41 11.2 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) TFIIA PF03153.13 CDJ68478.1 - 0.36 10.8 17.6 0.39 10.7 17.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ68478.1 - 0.46 8.5 32.7 0.54 8.3 32.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Tim54 PF11711.8 CDJ68478.1 - 0.47 9.2 4.3 0.5 9.1 4.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MPM1 PF17234.2 CDJ68478.1 - 0.48 10.7 8.1 0.62 10.3 8.1 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF4692 PF15763.5 CDJ68478.1 - 0.73 10.3 12.4 0.95 9.9 12.4 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Macoilin PF09726.9 CDJ68478.1 - 0.74 8.3 15.6 0.89 8.0 15.6 1.0 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CDJ68478.1 - 0.87 6.6 14.6 1 6.4 14.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SPX PF03105.19 CDJ68478.1 - 0.88 9.4 16.8 0.92 9.4 16.8 1.0 1 0 0 1 1 1 0 SPX domain Peptidase_M8 PF01457.16 CDJ68478.1 - 1.2 7.8 6.7 1.4 7.5 6.7 1.0 1 0 0 1 1 1 0 Leishmanolysin NST1 PF13945.6 CDJ68478.1 - 1.7 8.7 10.3 2.3 8.3 10.3 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator SLC12 PF03522.15 CDJ68478.1 - 1.8 7.5 5.0 2.1 7.3 5.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PAP1 PF08601.10 CDJ68478.1 - 2.6 7.7 21.2 3.3 7.4 21.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 SOG2 PF10428.9 CDJ68478.1 - 3.1 6.9 20.9 3.3 6.8 20.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2464 PF10240.9 CDJ68478.1 - 3.7 7.0 8.1 4.8 6.7 8.1 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 FAM220 PF15487.6 CDJ68478.1 - 3.8 7.1 12.3 4.5 6.8 12.3 1.0 1 0 0 1 1 1 0 FAM220 family CytochromB561_N PF09786.9 CDJ68478.1 - 4.6 6.1 17.4 5.2 5.9 17.4 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal CAF-1_p60_C PF15512.6 CDJ68478.1 - 5 7.6 21.3 6.6 7.2 21.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal Plasmodium_Vir PF05795.11 CDJ68478.1 - 6.3 6.1 8.8 7.5 5.9 8.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PI3K_1B_p101 PF10486.9 CDJ68478.1 - 6.6 4.4 12.3 8.1 4.1 12.3 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 CDJ68478.1 - 6.7 5.4 12.5 8.1 5.1 12.5 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ68478.1 - 6.9 5.2 15.4 7 5.2 15.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 CDJ68478.1 - 7.3 4.9 14.3 8.6 4.7 14.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 RSRP PF17069.5 CDJ68478.1 - 7.4 6.1 22.2 9.2 5.7 22.2 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 DUF4551 PF15087.6 CDJ68478.1 - 8 5.2 11.5 9.2 5.0 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Gti1_Pac2 PF09729.9 CDJ68478.1 - 8.1 6.5 10.6 10 6.1 10.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family PNISR PF15996.5 CDJ68478.1 - 8.2 6.6 11.1 11 6.3 11.1 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Roughex PF06020.11 CDJ68478.1 - 8.6 5.3 11.4 10 5.1 11.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF898 PF05987.13 CDJ68479.1 - 0.0089 15.1 7.6 0.022 13.8 7.6 1.7 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) PSII_BNR PF14870.6 CDJ68481.1 - 0.00071 18.9 0.2 0.0011 18.3 0.2 1.3 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 DUF2722 PF10846.8 CDJ68481.1 - 0.002 17.2 1.4 0.0025 16.8 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Reg_prop PF07494.11 CDJ68481.1 - 0.017 15.3 0.2 71 4.2 0.0 4.0 4 0 0 4 4 4 0 Two component regulator propeller Ribosomal_60s PF00428.19 CDJ68481.1 - 0.018 15.7 12.2 0.033 14.8 12.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Tachylectin PF14517.6 CDJ68481.1 - 0.12 11.9 0.1 0.71 9.4 0.1 2.2 1 1 0 1 1 1 0 Tachylectin Spt20 PF12090.8 CDJ68481.1 - 0.86 9.2 13.7 1.3 8.6 13.7 1.1 1 0 0 1 1 1 0 Spt20 family ELM2 PF01448.24 CDJ68482.1 - 0.01 16.6 0.1 0.03 15.1 0.1 1.8 1 0 0 1 1 1 0 ELM2 domain TFIIA PF03153.13 CDJ68482.1 - 0.015 15.3 16.4 0.021 14.8 16.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1501 PF07394.12 CDJ68482.1 - 4.7 6.2 16.2 5.5 5.9 16.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF3138 PF11336.8 CDJ68483.1 - 0.075 11.6 8.7 0.097 11.3 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2722 PF10846.8 CDJ68483.1 - 0.11 11.4 4.9 0.14 11.1 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MRP-L28 PF09812.9 CDJ68483.1 - 0.16 12.1 6.5 0.24 11.5 6.5 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 EPL1 PF10513.9 CDJ68486.1 - 0.013 15.9 23.0 0.028 14.8 10.8 3.3 3 0 0 3 3 2 0 Enhancer of polycomb-like SpoIIP PF07454.11 CDJ68486.1 - 0.14 11.6 22.4 0.031 13.8 14.5 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 CDJ68486.1 - 0.33 9.9 22.1 0.21 10.6 13.2 2.2 2 0 0 2 2 2 0 Solute carrier family 12 eIF-3_zeta PF05091.12 CDJ68486.1 - 0.34 9.8 29.7 0.11 11.4 21.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MecA PF05389.12 CDJ68486.1 - 0.48 10.0 18.7 0.64 9.6 10.8 3.1 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) Activator_LAG-3 PF11498.8 CDJ68486.1 - 0.66 8.9 64.4 0.15 11.0 47.0 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Peptidase_S49_N PF08496.10 CDJ68486.1 - 0.91 9.6 22.1 0.64 10.1 14.9 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ureide_permease PF07168.11 CDJ68486.1 - 0.98 8.1 13.7 0.019 13.7 5.7 2.1 2 0 0 2 2 2 0 Ureide permease Lin-8 PF03353.15 CDJ68486.1 - 1.2 8.7 41.4 0.023 14.3 16.1 3.8 4 0 0 4 4 4 0 Ras-mediated vulval-induction antagonist TERB2 PF15101.6 CDJ68486.1 - 1.3 9.1 38.0 2.4 8.2 24.2 3.0 2 0 0 2 2 2 0 Telomere-associated protein TERB2 SR-25 PF10500.9 CDJ68486.1 - 1.5 8.4 101.2 0.095 12.3 13.3 6.3 6 0 0 6 6 6 0 Nuclear RNA-splicing-associated protein HNOBA PF07701.14 CDJ68486.1 - 1.7 8.0 15.1 19 4.6 11.9 2.4 2 0 0 2 2 2 0 Heme NO binding associated DUF5523 PF17661.1 CDJ68486.1 - 1.7 8.2 20.2 0.12 12.0 12.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) SAPS PF04499.15 CDJ68486.1 - 2.2 7.0 17.2 0.69 8.6 10.2 2.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein EOS1 PF12326.8 CDJ68486.1 - 2.2 8.2 17.4 1.5 8.7 7.5 2.8 2 0 0 2 2 2 0 N-glycosylation protein Vfa1 PF08432.10 CDJ68486.1 - 2.5 8.4 25.5 1.1 9.5 16.6 2.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FAM76 PF16046.5 CDJ68486.1 - 2.7 7.3 26.8 0.35 10.2 13.2 2.6 2 0 0 2 2 2 0 FAM76 protein Eapp_C PF10238.9 CDJ68486.1 - 2.7 8.1 24.8 0.97 9.5 15.0 3.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4746 PF15928.5 CDJ68486.1 - 3.3 7.1 13.6 0.056 12.9 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF3408 PF11888.8 CDJ68486.1 - 3.7 7.7 23.7 0.45 10.7 13.9 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) MRP-S31 PF15433.6 CDJ68486.1 - 3.7 7.1 22.0 0.65 9.6 11.8 2.9 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Connexin PF00029.19 CDJ68486.1 - 4.2 7.0 19.3 0.74 9.5 12.0 2.2 2 0 0 2 2 2 0 Connexin CD20 PF04103.15 CDJ68486.1 - 5.2 7.1 6.6 2.6 8.1 0.1 2.9 2 0 0 2 2 2 0 CD20-like family MAT1 PF06391.13 CDJ68486.1 - 5.7 6.7 30.4 1.4 8.7 19.3 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 SID-1_RNA_chan PF13965.6 CDJ68486.1 - 6.1 5.1 14.4 0.58 8.5 6.5 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Mit_KHE1 PF10173.9 CDJ68486.1 - 6.4 6.8 12.2 5.1 7.1 0.3 2.7 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related FAM60A PF15396.6 CDJ68486.1 - 6.9 6.6 25.8 0.24 11.4 10.5 3.2 3 0 0 3 3 2 0 Protein Family FAM60A DUF3740 PF12548.8 CDJ68486.1 - 7.7 7.0 20.1 17 5.8 2.2 3.0 2 0 0 2 2 2 0 Sulfatase protein Serinc PF03348.15 CDJ68486.1 - 8.2 5.2 18.7 0.29 10.0 8.9 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) GCP_C_terminal PF04130.13 CDJ68488.1 - 4.8e-11 42.7 2.0 4.8e-11 42.7 2.0 1.9 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal HEAT_EZ PF13513.6 CDJ68488.1 - 0.047 14.2 0.2 0.047 14.2 0.2 2.8 3 1 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 CDJ68488.1 - 0.12 12.6 0.3 0.68 10.4 0.3 2.3 1 0 0 1 1 1 0 HEAT repeat PPC PF04151.15 CDJ68488.1 - 0.19 12.9 0.9 28 5.9 0.1 2.8 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Peptidase_M17_N PF02789.17 CDJ68488.1 - 0.79 9.6 5.5 2.1 8.2 1.0 2.5 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain GCP_N_terminal PF17681.1 CDJ68489.1 - 1.8e-33 116.5 6.0 1.8e-18 67.2 0.0 3.1 3 0 0 3 3 3 2 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CDJ68489.1 - 8.9e-05 22.1 2.6 8.9e-05 22.1 2.6 3.0 3 1 0 3 3 3 1 Gamma tubulin complex component C-terminal SR-25 PF10500.9 CDJ68490.1 - 0.06 12.9 31.0 0.7 9.5 5.6 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 CDJ68490.1 - 0.087 9.9 18.2 0.11 9.6 18.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PRCH PF03967.13 CDJ68490.1 - 0.16 12.2 0.4 0.34 11.2 0.4 1.5 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region DUF4551 PF15087.6 CDJ68490.1 - 4.6 5.9 14.5 6.1 5.6 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Tmemb_cc2 PF10267.9 CDJ68490.1 - 6.9 5.7 12.3 8.8 5.3 12.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF755 PF05501.11 CDJ68490.1 - 9.3 6.5 34.6 0.44 10.8 2.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF755) DTW PF03942.15 CDJ68493.1 - 8.8e-06 25.6 8.3 4.5e-05 23.3 0.8 3.4 2 1 0 2 2 2 1 DTW domain RskA PF10099.9 CDJ68493.1 - 0.00017 22.0 21.0 0.00017 22.0 21.0 5.9 1 1 3 5 5 5 1 Anti-sigma-K factor rskA SID-1_RNA_chan PF13965.6 CDJ68493.1 - 0.0081 14.6 2.1 0.015 13.7 2.1 1.4 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 EPL1 PF10513.9 CDJ68493.1 - 0.19 12.1 27.8 4.1 7.8 0.4 3.3 3 0 0 3 3 3 0 Enhancer of polycomb-like AUX_IAA PF02309.16 CDJ68493.1 - 0.45 10.3 0.0 0.45 10.3 0.0 3.2 1 1 1 2 2 2 0 AUX/IAA family O-antigen_lig PF13425.6 CDJ68493.1 - 3.3 6.4 6.9 5.6 5.6 6.9 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein LMBR1 PF04791.16 CDJ68493.1 - 4.7 6.0 4.6 7 5.4 4.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1635 PF07795.11 CDJ68494.1 - 0.001 19.0 9.7 0.001 19.0 9.7 9.1 4 2 4 8 8 8 2 Protein of unknown function (DUF1635) DUF755 PF05501.11 CDJ68494.1 - 0.0065 16.7 20.4 0.0065 16.7 20.4 10.8 7 2 3 11 11 11 2 Domain of unknown function (DUF755) RskA PF10099.9 CDJ68494.1 - 0.0072 16.6 11.6 0.0072 16.6 11.6 13.3 4 2 6 10 10 10 1 Anti-sigma-K factor rskA PfkB PF00294.24 CDJ68496.1 - 1.3e-17 64.1 0.0 4.6e-13 49.1 0.0 2.3 1 1 1 2 2 2 2 pfkB family carbohydrate kinase DUF2052 PF09747.9 CDJ68496.1 - 0.16 12.1 21.1 0.24 11.5 21.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ68496.1 - 0.21 11.4 21.9 0.3 10.9 21.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 CDJ68496.1 - 0.23 9.5 19.3 0.29 9.2 19.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein XRN_M PF17846.1 CDJ68496.1 - 0.51 9.2 11.6 0.69 8.8 11.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain SLC12 PF03522.15 CDJ68496.1 - 0.53 9.2 23.1 0.75 8.8 23.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 CDJ68496.1 - 0.58 8.4 19.1 0.82 7.9 19.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Endostatin PF06482.11 CDJ68496.1 - 0.77 9.2 18.8 1.3 8.4 18.8 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Presenilin PF01080.17 CDJ68496.1 - 2 7.1 32.1 2.8 6.6 32.1 1.1 1 0 0 1 1 1 0 Presenilin SKA1 PF07160.12 CDJ68496.1 - 2 8.2 21.8 3 7.6 21.8 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF2151 PF10221.9 CDJ68496.1 - 3.4 6.1 15.2 4.8 5.6 15.2 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator SRP-alpha_N PF04086.13 CDJ68496.1 - 4.4 7.2 23.8 6 6.7 23.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PAT1 PF09770.9 CDJ68496.1 - 4.7 5.4 42.2 6 5.0 42.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.6 CDJ68496.1 - 6.8 6.0 22.6 9 5.5 22.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Auxin_canalis PF05703.11 CDJ68496.1 - 9.1 6.1 10.1 12 5.7 10.1 1.2 1 0 0 1 1 1 0 Auxin canalisation Neur_chan_memb PF02932.16 CDJ68496.1 - 9.3 6.2 22.7 15 5.5 22.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4201 PF13870.6 CDJ68499.1 - 1.5e-19 70.5 25.2 3.3e-19 69.3 25.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) MCM6_C PF18263.1 CDJ68499.1 - 0.38 11.0 0.1 0.38 11.0 0.1 3.1 2 1 1 3 3 3 0 MCM6 C-terminal winged-helix domain Ank_2 PF12796.7 CDJ68500.1 - 9.1e-25 87.1 10.5 7.3e-07 29.7 6.1 4.8 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ68500.1 - 3.8e-24 84.4 17.1 8.8e-11 41.8 0.5 5.6 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ68500.1 - 1.8e-23 82.6 14.5 1e-06 29.1 1.3 6.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 CDJ68500.1 - 3.5e-19 68.3 26.1 0.0024 18.2 0.1 8.2 7 1 1 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 CDJ68500.1 - 8.8e-16 56.4 11.1 0.22 12.2 0.2 7.9 7 0 0 7 7 7 5 Ankyrin repeat Sushi PF00084.20 CDJ68500.1 - 4e-08 33.7 0.2 8.2e-08 32.7 0.2 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DnaJ PF00226.31 CDJ68501.1 - 1.2e-19 70.1 0.4 2.6e-19 69.1 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 CDJ68501.1 - 9.8e-19 67.5 0.0 1.4e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain ETRAMP PF09716.10 CDJ68501.1 - 8.1 6.6 5.3 1.2 9.3 0.0 2.3 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) zf-CCHC_5 PF14787.6 CDJ68502.1 - 0.037 13.7 0.4 0.099 12.4 0.4 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Dynein_light PF01221.18 CDJ68504.1 - 2.6e-21 75.7 0.1 2.9e-21 75.6 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 zf-4CXXC_R1 PF10497.9 CDJ68504.1 - 0.0061 16.8 0.0 0.0064 16.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Ribosomal_L27 PF01016.19 CDJ68505.1 - 2.1e-11 43.7 0.5 8.2e-11 41.8 0.5 1.8 1 1 0 1 1 1 1 Ribosomal L27 protein Spt20 PF12090.8 CDJ68506.1 - 0.095 12.3 57.8 0.024 14.3 3.7 4.3 4 0 0 4 4 4 0 Spt20 family Chorein_N PF12624.7 CDJ68506.1 - 0.1 12.7 0.1 0.1 12.7 0.1 4.2 4 0 0 4 4 4 0 N-terminal region of Chorein or VPS13 GBP PF02263.19 CDJ68507.1 - 1e-10 41.4 6.3 6.2e-07 28.9 0.0 3.1 3 0 0 3 3 3 2 Guanylate-binding protein, N-terminal domain RskA PF10099.9 CDJ68507.1 - 0.00026 21.3 14.2 0.00026 21.3 14.2 7.9 5 3 0 6 6 6 2 Anti-sigma-K factor rskA DUF1645 PF07816.11 CDJ68507.1 - 0.0076 16.8 2.2 0.0076 16.8 2.2 8.6 4 2 3 9 9 9 1 Protein of unknown function (DUF1645) SLBP_RNA_bind PF15247.6 CDJ68508.1 - 1e-17 64.0 2.2 1e-17 64.0 2.2 2.9 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain SR-25 PF10500.9 CDJ68508.1 - 2.5e-05 24.0 18.5 2.5e-05 24.0 18.5 4.7 3 1 2 5 5 5 2 Nuclear RNA-splicing-associated protein MAGE PF01454.19 CDJ68508.1 - 0.0088 15.8 1.9 0.0088 15.8 1.9 3.7 3 1 0 3 3 3 1 MAGE family SAGA-Tad1 PF12767.7 CDJ68508.1 - 6.5 6.4 32.2 0.13 12.0 1.8 3.2 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit CPW_WPC PF09717.10 CDJ68509.1 - 8.5e-12 45.9 8.0 4.1e-06 27.7 0.7 3.5 3 1 0 3 3 3 2 Plasmodium falciparum domain of unknown function (CPW_WPC) FAM196 PF15265.6 CDJ68510.1 - 0.12 11.9 12.4 0.14 11.6 12.4 1.2 1 0 0 1 1 1 0 FAM196 family VIT_2 PF13757.6 CDJ68511.1 - 7.3 6.6 6.8 21 5.1 0.2 2.6 1 1 1 2 2 2 0 Vault protein inter-alpha-trypsin domain Prefoldin_2 PF01920.20 CDJ68512.1 - 4.5e-05 23.3 3.7 5.3e-05 23.1 3.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit 2-Hacid_dh_C PF02826.19 CDJ68512.1 - 0.0018 17.7 0.2 0.0019 17.6 0.2 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Spt20 PF12090.8 CDJ68512.1 - 0.0031 17.2 9.9 0.0031 17.2 9.9 1.1 1 0 0 1 1 1 1 Spt20 family Rpp20 PF12328.8 CDJ68512.1 - 0.012 15.6 0.1 0.012 15.6 0.1 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF2722 PF10846.8 CDJ68512.1 - 0.013 14.4 6.6 0.013 14.5 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) mRNA_cap_enzyme PF01331.19 CDJ68512.1 - 0.023 14.5 0.0 0.026 14.4 0.0 1.0 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain APO_RNA-bind PF05634.11 CDJ68512.1 - 0.038 13.4 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 APO RNA-binding EIIBC-GUT_N PF03612.14 CDJ68512.1 - 0.1 12.3 0.2 0.14 11.9 0.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TFIIA PF03153.13 CDJ68512.1 - 0.16 11.9 10.4 0.15 12.0 10.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PepSY_TM PF03929.16 CDJ68512.1 - 0.25 11.0 2.0 0.27 10.9 2.0 1.0 1 0 0 1 1 1 0 PepSY-associated TM region Med3 PF11593.8 CDJ68512.1 - 4.9 6.2 14.1 6.1 5.9 14.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Androgen_recep PF02166.16 CDJ68512.1 - 6.1 5.6 18.3 9 5.0 18.3 1.3 1 0 0 1 1 1 0 Androgen receptor DUF4471 PF14740.6 CDJ68513.1 - 0.16 11.2 10.1 0.17 11.1 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) SpoIIP PF07454.11 CDJ68513.1 - 0.2 11.1 17.1 0.2 11.1 17.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PPL5 PF18168.1 CDJ68513.1 - 0.2 10.9 9.5 0.22 10.8 9.5 1.2 1 0 0 1 1 1 0 Prim-pol family 5 tRNA_synt_1c_R2 PF04557.15 CDJ68513.1 - 0.48 11.4 12.5 0.79 10.7 12.5 1.5 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DDRGK PF09756.9 CDJ68513.1 - 0.79 9.3 24.7 0.96 9.0 24.7 1.3 1 0 0 1 1 1 0 DDRGK domain Presenilin PF01080.17 CDJ68513.1 - 0.9 8.2 20.8 0.92 8.2 20.8 1.1 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 CDJ68513.1 - 1.1 8.0 12.9 1.1 8.1 12.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Otopetrin PF03189.13 CDJ68513.1 - 1.2 7.9 5.8 1.1 8.0 5.8 1.2 1 0 0 1 1 1 0 Otopetrin NPR3 PF03666.13 CDJ68513.1 - 1.4 7.7 15.8 1.4 7.6 15.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 CDJ68513.1 - 2 7.1 15.3 2.2 7.0 15.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 CDJ68513.1 - 2 7.5 5.6 1.8 7.7 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RPA43_OB PF17875.1 CDJ68513.1 - 2.8 8.6 11.8 4.5 7.9 11.8 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I OATP PF03137.20 CDJ68513.1 - 3.2 5.9 9.9 3.3 5.9 9.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Plasmodium_Vir PF05795.11 CDJ68513.1 - 3.2 7.1 8.2 2.7 7.3 8.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CCDC53 PF10152.9 CDJ68513.1 - 3.4 8.1 19.6 6.1 7.2 19.6 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex ABC2_membrane_2 PF12679.7 CDJ68513.1 - 3.9 6.7 4.2 3.5 6.8 4.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein NARP1 PF12569.8 CDJ68513.1 - 4 6.2 18.5 4.3 6.1 18.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM91_C PF14648.6 CDJ68513.1 - 5.2 5.8 8.5 5.2 5.8 8.5 1.2 1 0 0 1 1 1 0 FAM91 C-terminus SAPS PF04499.15 CDJ68513.1 - 6.5 5.4 14.6 39 2.8 0.0 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Peptidase_S64 PF08192.11 CDJ68513.1 - 6.8 5.1 18.0 7.2 5.0 18.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 eIF3_subunit PF08597.10 CDJ68513.1 - 8.2 6.3 19.6 9.7 6.0 19.6 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit zf-C3HC4_2 PF13923.6 CDJ68514.1 - 4.8e-08 32.7 12.4 1.6e-07 31.0 12.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ68514.1 - 4.6e-07 30.1 11.6 1.4e-06 28.5 11.6 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ68514.1 - 1.7e-06 27.8 9.2 4.5e-06 26.4 9.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ68514.1 - 4.6e-05 23.4 11.6 0.00018 21.4 11.6 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ68514.1 - 7.7e-05 22.5 11.3 7.7e-05 22.5 11.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ68514.1 - 9.6e-05 22.3 9.8 9.6e-05 22.3 9.8 2.3 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ68514.1 - 0.00012 21.8 9.9 0.00045 20.0 9.9 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CDJ68514.1 - 0.001 18.9 4.3 0.0025 17.6 4.3 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CDJ68514.1 - 0.0023 18.1 14.5 0.0095 16.1 14.5 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Peptidase_C97 PF05903.14 CDJ68514.1 - 0.034 14.0 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain U-box PF04564.15 CDJ68514.1 - 0.059 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.7 CDJ68514.1 - 0.34 11.2 7.7 2.2 8.6 7.7 2.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain eIF-3_zeta PF05091.12 CDJ68515.1 - 2.5 7.0 25.8 2.8 6.8 25.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ68516.1 - 0.091 11.0 11.7 0.093 11.0 11.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IMUP PF15761.5 CDJ68517.1 - 0.12 13.0 15.2 1.5 9.6 2.9 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein RTX PF02382.15 CDJ68518.1 - 0.005 16.6 13.0 0.0064 16.2 12.9 1.2 1 1 0 1 1 1 1 N-terminal domain in RTX protein DUF677 PF05055.12 CDJ68518.1 - 0.022 13.7 8.6 0.032 13.1 8.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF677) Esterase PF00756.20 CDJ68518.1 - 0.1 12.2 7.7 0.12 12.0 7.7 1.1 1 0 0 1 1 1 0 Putative esterase V_ATPase_I PF01496.19 CDJ68518.1 - 0.5 8.2 19.4 0.58 8.0 19.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_1 PF00515.28 CDJ68519.1 - 8.3e-06 25.4 4.7 0.0098 15.7 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ68519.1 - 0.0014 18.6 0.1 0.0014 18.6 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat Condensin2nSMC PF12422.8 CDJ68519.1 - 0.034 14.3 0.5 0.081 13.1 0.5 1.6 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Secretin_N_2 PF07655.13 CDJ68519.1 - 0.04 14.5 11.1 0.071 13.7 11.1 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain RAP1 PF07218.11 CDJ68519.1 - 0.041 12.2 4.4 0.055 11.8 4.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S64 PF08192.11 CDJ68519.1 - 0.37 9.2 6.6 0.5 8.8 6.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Uteroglobin PF01099.17 CDJ68519.1 - 0.53 10.7 4.3 0.46 10.8 1.7 2.2 2 0 0 2 2 2 0 Uteroglobin family Mit_KHE1 PF10173.9 CDJ68519.1 - 0.55 10.3 3.2 0.42 10.7 1.1 1.9 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Vps39_1 PF10366.9 CDJ68519.1 - 2.3 8.5 7.4 1.6 9.1 2.5 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 SPX PF03105.19 CDJ68521.1 - 0.17 11.8 4.4 0.24 11.3 4.4 1.3 1 0 0 1 1 1 0 SPX domain PAP1 PF08601.10 CDJ68521.1 - 0.63 9.7 12.9 0.91 9.2 12.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Sporozoite_P67 PF05642.11 CDJ68521.1 - 0.65 8.0 9.0 0.81 7.7 9.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MAGE_N PF12440.8 CDJ68521.1 - 0.68 10.7 29.3 0.15 12.7 12.2 3.0 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal UCR_Fe-S_N PF10399.9 CDJ68521.1 - 0.71 9.3 0.0 0.71 9.3 0.0 3.5 3 0 0 3 3 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal CCDC24 PF15669.5 CDJ68521.1 - 1.2 9.0 8.8 0.46 10.3 5.9 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family RAP1 PF07218.11 CDJ68521.1 - 1.8 6.7 20.8 2.5 6.3 20.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 CDJ68521.1 - 2.2 6.8 11.7 3.2 6.2 11.7 1.2 1 0 0 1 1 1 0 Macoilin family Secretin_N_2 PF07655.13 CDJ68521.1 - 2.2 8.9 19.7 4.3 8.0 19.7 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain AF-4 PF05110.13 CDJ68521.1 - 2.3 6.2 22.2 3.1 5.7 22.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CAP_N PF01213.19 CDJ68521.1 - 3.8 6.9 12.7 0.77 9.2 4.5 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Apt1 PF10351.9 CDJ68521.1 - 5.5 5.7 8.5 7.6 5.3 8.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC106 PF15794.5 CDJ68521.1 - 9.4 5.9 11.2 17 5.0 11.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF1645 PF07816.11 CDJ68521.1 - 9.7 6.7 19.7 3.8e+02 1.5 20.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) BAF1_ABF1 PF04684.13 CDJ68522.1 - 0.0035 16.5 0.2 0.0051 15.9 0.2 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor zf-HIT PF04438.16 CDJ68522.1 - 0.11 12.4 14.6 0.19 11.6 14.6 1.4 1 0 0 1 1 1 0 HIT zinc finger Activator_LAG-3 PF11498.8 CDJ68522.1 - 5 6.0 29.6 1.1 8.2 23.1 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Lin-8 PF03353.15 CDJ68522.1 - 6.7 6.2 10.9 18 4.8 9.8 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist PAPS_reduct PF01507.19 CDJ68523.1 - 6.9e-19 68.5 7.0 2.1e-11 44.2 0.0 3.8 2 1 1 3 3 3 2 Phosphoadenosine phosphosulfate reductase family TFIIA PF03153.13 CDJ68523.1 - 0.0002 21.5 76.2 0.0028 17.7 42.9 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ68523.1 - 0.0012 17.9 12.0 0.0012 17.9 12.0 4.7 3 1 1 5 5 5 1 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ68523.1 - 0.0044 15.8 15.6 0.0044 15.8 15.6 3.2 3 1 0 3 3 3 1 Presenilin Scs3p PF10261.9 CDJ68523.1 - 0.092 12.2 4.1 0.13 11.7 3.2 1.7 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Utp14 PF04615.13 CDJ68523.1 - 1.3 7.5 53.6 1.9 6.9 16.0 2.2 2 0 0 2 2 2 0 Utp14 protein Suf PF05843.14 CDJ68524.1 - 0.049 13.6 4.5 0.071 13.1 4.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ68524.1 - 4 7.3 20.6 0.27 11.2 15.4 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ68524.1 - 6.9 6.2 21.6 9 5.8 21.6 1.1 1 0 0 1 1 1 0 Spt20 family NOA36 PF06524.12 CDJ68525.1 - 0.0032 16.8 12.9 0.0043 16.4 12.9 1.2 1 0 0 1 1 1 1 NOA36 protein CENP-B_dimeris PF09026.10 CDJ68525.1 - 0.0092 16.4 13.0 0.015 15.6 13.0 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain GCIP PF13324.6 CDJ68525.1 - 0.012 15.2 4.2 0.015 14.9 4.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 CDJ68525.1 - 0.013 13.8 2.6 0.012 13.8 2.6 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 CDJ68525.1 - 0.022 14.3 5.4 0.031 13.9 5.4 1.1 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 CDJ68525.1 - 0.022 13.1 1.6 0.022 13.1 1.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 CDJ68525.1 - 0.03 14.6 9.2 0.049 13.9 9.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CNDH2_C PF16858.5 CDJ68525.1 - 0.1 12.4 1.2 0.13 12.2 1.2 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Cwf_Cwc_15 PF04889.12 CDJ68525.1 - 0.2 11.4 16.0 0.38 10.4 16.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 CDJ68525.1 - 0.26 11.0 1.8 0.41 10.3 1.8 1.4 1 0 0 1 1 1 0 FAM176 family BSP_II PF05432.11 CDJ68525.1 - 0.27 10.9 3.7 0.4 10.3 3.7 1.3 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) BUD22 PF09073.10 CDJ68525.1 - 0.53 9.6 17.2 0.68 9.2 17.2 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 CDJ68525.1 - 0.56 8.7 5.5 0.68 8.4 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 CDJ68525.1 - 1.6 6.7 16.4 2.1 6.3 16.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 CDJ68525.1 - 4.1 7.4 7.7 6.3 6.8 7.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 CDJ68525.1 - 4.3 7.8 14.3 9.2 6.7 14.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Bromodomain PF00439.25 CDJ68526.1 - 4.2e-06 26.7 0.0 6.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain SR-25 PF10500.9 CDJ68526.1 - 0.011 15.3 15.2 0.011 15.3 15.2 2.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ68526.1 - 0.12 12.5 7.5 0.045 13.8 3.7 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DEAD PF00270.29 CDJ68527.1 - 2.8e-31 108.7 0.0 4.2e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 CDJ68527.1 - 1.1e-09 38.4 0.0 2.6e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CDJ68527.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ndc1_Nup PF09531.10 CDJ68527.1 - 0.27 9.9 4.5 0.28 9.8 4.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cwf_Cwc_15 PF04889.12 CDJ68527.1 - 3.5 7.3 14.3 5.2 6.7 14.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPH PF13868.6 CDJ68528.1 - 4.8e-27 94.4 154.2 4.8e-27 94.4 154.2 2.1 1 1 0 2 2 2 2 Trichohyalin-plectin-homology domain SUIM_assoc PF16619.5 CDJ68529.1 - 0.0057 16.7 1.4 0.0057 16.7 1.4 1.5 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 ATP-synt_E PF05680.12 CDJ68529.1 - 0.049 14.0 0.5 0.069 13.5 0.5 1.2 1 0 0 1 1 1 0 ATP synthase E chain DUF4736 PF15883.5 CDJ68529.1 - 0.7 9.6 4.9 1.1 9.0 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) ANAPC_CDC26 PF10471.9 CDJ68529.1 - 1.3 9.9 11.0 2 9.3 11.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 ELO PF01151.18 CDJ68530.1 - 1.2e-46 159.3 22.0 1.5e-46 159.0 22.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Kelch_4 PF13418.6 CDJ68531.1 - 0.0085 16.1 0.9 0.015 15.3 0.9 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain Lin-8 PF03353.15 CDJ68531.1 - 0.011 15.3 15.3 0.015 14.9 15.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ68531.1 - 0.013 15.5 15.7 0.016 15.1 15.7 1.4 1 0 0 1 1 1 0 SPX domain Kelch_5 PF13854.6 CDJ68531.1 - 0.016 15.2 0.4 0.065 13.2 0.4 2.2 1 0 0 1 1 1 0 Kelch motif MRP-S31 PF15433.6 CDJ68531.1 - 0.026 14.2 12.1 0.037 13.7 12.1 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Macoilin PF09726.9 CDJ68531.1 - 0.21 10.1 18.7 0.29 9.7 18.7 1.2 1 0 0 1 1 1 0 Macoilin family Spc7_N PF15402.6 CDJ68531.1 - 1.8 6.7 24.6 2.1 6.5 24.6 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 GREB1 PF15782.5 CDJ68531.1 - 2.6 5.0 25.5 3.3 4.7 25.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NST1 PF13945.6 CDJ68531.1 - 4.5 7.3 19.4 6.6 6.8 19.4 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Miga PF10265.9 CDJ68531.1 - 5.9 5.7 15.6 8 5.3 15.6 1.2 1 0 0 1 1 1 0 Mitoguardin CECR6_TMEM121 PF14997.6 CDJ68532.1 - 6.8e-07 29.3 1.1 1.1e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 CECR6/TMEM121 family Tmem26 PF09772.9 CDJ68532.1 - 0.017 14.5 0.7 0.058 12.7 0.7 1.9 1 0 0 1 1 1 0 Transmembrane protein 26 TFIIA PF03153.13 CDJ68532.1 - 0.021 14.8 32.9 0.36 10.8 0.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Methyltransf_23 PF13489.6 CDJ68532.1 - 4.6 7.1 5.3 1.7 8.5 0.2 2.3 2 0 0 2 2 2 0 Methyltransferase domain PqqD PF05402.12 CDJ68534.1 - 0.095 13.0 0.1 0.58 10.5 0.0 2.3 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) EIF4E-T PF10477.9 CDJ68534.1 - 0.72 8.6 9.2 0.96 8.2 9.2 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Med3 PF11593.8 CDJ68535.1 - 0.03 13.5 15.3 0.034 13.3 15.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_60s PF00428.19 CDJ68535.1 - 0.075 13.6 5.0 0.083 13.5 5.0 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein TraG_N PF07916.11 CDJ68535.1 - 0.6 8.9 11.4 0.67 8.7 11.4 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF4820 PF16091.5 CDJ68535.1 - 2.5 7.4 9.0 2.5 7.4 9.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CCDC53 PF10152.9 CDJ68535.1 - 4.4 7.7 8.4 5 7.5 8.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2477 PF10631.9 CDJ68535.1 - 9.3 6.9 10.8 10 6.8 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Suf PF05843.14 CDJ68536.1 - 0.012 15.6 8.9 0.015 15.3 8.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RskA PF10099.9 CDJ68536.1 - 0.053 13.8 29.9 0.28 11.5 2.7 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Orf78 PF06024.12 CDJ68536.1 - 0.39 11.0 5.5 0.91 9.9 5.5 1.7 1 0 0 1 1 1 0 Orf78 (ac78) DUF4834 PF16118.5 CDJ68536.1 - 0.51 11.3 10.5 0.96 10.5 10.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SpoIIP PF07454.11 CDJ68536.1 - 0.86 9.0 9.9 1.3 8.4 9.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CDJ68536.1 - 0.86 8.3 9.5 1.1 7.9 9.5 1.2 1 0 0 1 1 1 0 Presenilin EIF4E-T PF10477.9 CDJ68536.1 - 2.2 7.0 17.6 2.4 6.9 17.6 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E AIF_C PF14721.6 CDJ68536.1 - 2.5 8.5 7.0 5.3 7.4 7.0 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ctr PF04145.15 CDJ68536.1 - 6.8 7.3 9.8 24 5.5 6.7 2.2 2 0 0 2 2 2 0 Ctr copper transporter family DUF3807 PF12720.7 CDJ68537.1 - 0.0095 16.2 13.8 0.0095 16.2 13.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3807) TraT PF05818.12 CDJ68537.1 - 0.013 15.2 19.3 0.013 15.2 19.3 2.6 2 1 0 2 2 1 0 Enterobacterial TraT complement resistance protein DUF1772 PF08592.11 CDJ68537.1 - 0.016 15.5 5.3 0.016 15.5 5.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) OSTbeta PF15048.6 CDJ68537.1 - 0.072 13.2 4.1 0.2 11.8 4.1 1.7 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Cellulose_synt PF03552.14 CDJ68537.1 - 0.16 10.4 5.4 0.2 10.1 5.4 1.2 1 0 0 1 1 1 0 Cellulose synthase Utp14 PF04615.13 CDJ68537.1 - 0.28 9.7 32.9 0.37 9.3 32.9 1.3 1 0 0 1 1 1 0 Utp14 protein WASH-7_C PF14746.6 CDJ68537.1 - 0.6 9.8 14.0 1.5 8.5 14.0 1.6 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal FPN1 PF06963.12 CDJ68537.1 - 0.78 8.2 6.7 1.4 7.4 6.7 1.4 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF2232 PF09991.9 CDJ68537.1 - 0.85 8.7 5.5 1.3 8.2 5.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Nucleoside_tran PF01733.18 CDJ68537.1 - 1.1 8.5 2.8 1.8 7.9 2.8 1.3 1 0 0 1 1 1 0 Nucleoside transporter CD20 PF04103.15 CDJ68537.1 - 1.2 9.2 5.5 0.39 10.8 0.9 2.3 2 1 0 2 2 2 0 CD20-like family SID-1_RNA_chan PF13965.6 CDJ68537.1 - 1.3 7.3 12.2 0.047 12.1 4.6 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 CDJ68537.1 - 2.4 7.1 18.1 0.015 14.3 7.8 2.0 2 0 0 2 2 2 0 CLN3 protein V_ATPase_I PF01496.19 CDJ68537.1 - 4 5.2 23.8 0.01 13.8 13.5 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family O-antigen_lig PF13425.6 CDJ68537.1 - 4.4 6.0 6.9 5.7 5.6 6.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein BAF1_ABF1 PF04684.13 CDJ68537.1 - 5.6 5.9 37.2 0.79 8.7 15.4 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor OATP PF03137.20 CDJ68537.1 - 6.5 4.9 13.9 0.1 10.9 6.6 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ureide_permease PF07168.11 CDJ68537.1 - 9.2 4.9 13.1 0.78 8.4 7.6 1.9 1 1 1 2 2 2 0 Ureide permease OSTbeta PF15048.6 CDJ68538.1 - 0.037 14.1 0.0 0.18 11.9 0.0 2.2 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein Activator_LAG-3 PF11498.8 CDJ68539.1 - 0.0046 16.0 25.9 0.0046 16.0 25.9 5.3 4 1 1 5 5 5 2 Transcriptional activator LAG-3 RskA PF10099.9 CDJ68539.1 - 0.0082 16.5 17.0 0.0082 16.5 17.0 11.0 3 2 4 8 8 8 1 Anti-sigma-K factor rskA LptF_LptG PF03739.14 CDJ68540.1 - 0.39 9.5 12.1 0.6 8.9 12.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Shadoo PF14999.6 CDJ68540.1 - 5.1 7.2 16.1 1.3 9.1 9.0 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF2722 PF10846.8 CDJ68541.1 - 0.0088 15.0 0.2 0.0088 15.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ68541.1 - 0.075 12.6 6.3 0.093 12.3 6.3 1.1 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ68541.1 - 1.3 9.3 17.9 4 7.7 10.3 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ68542.1 - 0.00092 18.9 9.6 0.00097 18.8 9.6 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ68542.1 - 0.0011 19.0 15.3 0.0013 18.8 15.3 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ68542.1 - 0.014 15.7 13.4 0.017 15.5 13.4 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TraT PF05818.12 CDJ68542.1 - 0.023 14.4 2.8 0.029 14.1 2.8 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF2722 PF10846.8 CDJ68542.1 - 0.029 13.3 10.4 0.04 12.9 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Macoilin PF09726.9 CDJ68542.1 - 0.059 11.9 3.8 0.073 11.6 3.8 1.0 1 0 0 1 1 1 0 Macoilin family DUF4824 PF16106.5 CDJ68542.1 - 0.063 12.5 3.9 0.03 13.6 1.9 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4824) Lin-8 PF03353.15 CDJ68542.1 - 0.082 12.5 4.2 0.093 12.3 4.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Rsc14 PF08586.10 CDJ68542.1 - 0.094 13.5 0.4 0.14 13.0 0.4 1.3 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit Protamine_P2 PF00841.19 CDJ68542.1 - 1.9 9.0 8.5 3.1 8.4 8.5 1.3 1 0 0 1 1 1 0 Sperm histone P2 DUF1645 PF07816.11 CDJ68542.1 - 4.4 7.8 11.2 1.9 9.0 8.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1645) Syntaphilin PF15290.6 CDJ68542.1 - 7.8 6.1 19.9 2.1 7.9 10.1 2.1 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp DUF5349 PF17298.2 CDJ68543.1 - 0.021 14.6 5.3 0.024 14.4 5.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Med15 PF09606.10 CDJ68543.1 - 0.11 11.2 12.2 0.11 11.2 12.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Androgen_recep PF02166.16 CDJ68543.1 - 0.12 11.2 12.2 0.13 11.1 12.2 1.1 1 0 0 1 1 1 0 Androgen receptor Activator_LAG-3 PF11498.8 CDJ68543.1 - 0.14 11.1 17.1 0.16 10.9 17.1 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PDZ_5 PF17817.1 CDJ68543.1 - 0.21 11.9 0.0 0.26 11.6 0.0 1.1 1 0 0 1 1 1 0 PDZ domain Spt20 PF12090.8 CDJ68543.1 - 0.51 9.9 12.7 0.53 9.8 12.7 1.0 1 0 0 1 1 1 0 Spt20 family DUF4519 PF15012.6 CDJ68543.1 - 1.3 9.2 4.2 2 8.7 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF2722 PF10846.8 CDJ68543.1 - 1.6 7.6 11.7 1.8 7.4 11.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ68544.1 - 8.4e-06 26.2 1.5 8.4e-06 26.2 1.5 8.4 3 2 2 5 5 5 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ68544.1 - 0.0043 17.6 5.8 0.0043 17.6 5.8 7.2 7 1 1 8 8 8 1 60s Acidic ribosomal protein Phos_pyr_kin PF08543.12 CDJ68546.1 - 2.5e-07 30.3 0.5 8.3e-05 22.1 0.0 3.0 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CDJ68546.1 - 0.00035 20.0 6.5 0.0063 15.8 0.0 3.0 2 1 0 3 3 3 2 pfkB family carbohydrate kinase Efg1 PF10153.9 CDJ68546.1 - 0.0061 16.9 2.2 0.013 15.9 0.1 2.3 2 0 0 2 2 2 1 rRNA-processing protein Efg1 KAsynt_C_assoc PF16197.5 CDJ68546.1 - 0.024 15.1 0.2 0.069 13.6 0.2 1.8 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension RskA PF10099.9 CDJ68546.1 - 2.8 8.2 42.2 0.12 12.6 6.0 3.6 1 1 2 3 3 3 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ68546.1 - 6.5 6.3 12.6 2.7 7.5 8.7 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ68546.1 - 7.7 6.7 35.0 4.8 7.3 4.1 4.3 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 SKA1 PF07160.12 CDJ68547.1 - 0.13 12.0 6.8 0.15 11.9 6.8 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 RRP36 PF06102.12 CDJ68547.1 - 0.29 11.1 6.2 0.39 10.7 6.2 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Cytadhesin_P30 PF07271.11 CDJ68547.1 - 1.7 8.1 11.4 2.1 7.8 11.4 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Virul_Fac PF10139.9 CDJ68547.1 - 3.1 5.9 10.9 3.6 5.7 10.9 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor DLIC PF05783.11 CDJ68547.1 - 6 5.6 8.2 6.9 5.4 8.2 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) CDK2AP PF09806.9 CDJ68547.1 - 7.2 6.6 16.5 10 6.1 16.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF572 PF04502.13 CDJ68548.1 - 0.044 13.4 26.3 0.065 12.8 26.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S49_N PF08496.10 CDJ68548.1 - 0.063 13.3 19.0 0.33 11.0 12.2 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AF-4 PF05110.13 CDJ68548.1 - 0.19 9.8 37.6 0.22 9.5 37.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_S2 PF00318.20 CDJ68548.1 - 3.4 6.8 9.2 18 4.5 5.3 2.3 2 0 0 2 2 2 0 Ribosomal protein S2 TFB6 PF17110.5 CDJ68548.1 - 7.9 6.2 11.1 11 5.7 7.3 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH RNB PF00773.19 CDJ68549.1 - 1.3e-17 64.1 8.9 5.2e-17 62.2 8.9 1.8 1 1 0 1 1 1 1 RNB domain DUF4667 PF15700.5 CDJ68549.1 - 3.3e-05 24.1 12.4 4e-05 23.8 12.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) TAF4 PF05236.14 CDJ68549.1 - 0.00015 21.6 5.6 0.00019 21.3 5.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF5349 PF17298.2 CDJ68549.1 - 0.0013 18.6 19.8 0.0015 18.3 19.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5349) Lin-8 PF03353.15 CDJ68549.1 - 0.0048 16.5 10.7 0.0055 16.3 10.7 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ68549.1 - 0.0056 15.3 10.4 0.0067 15.1 10.4 1.1 1 0 0 1 1 1 1 Macoilin family Med15 PF09606.10 CDJ68549.1 - 0.0071 15.1 16.4 0.0095 14.7 16.4 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Apt1 PF10351.9 CDJ68549.1 - 0.0077 15.1 7.2 0.0084 15.0 7.2 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain MAP65_ASE1 PF03999.12 CDJ68549.1 - 0.0085 14.8 6.1 0.011 14.5 6.1 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) PAP1 PF08601.10 CDJ68549.1 - 0.019 14.7 15.0 0.021 14.6 15.0 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Pex14_N PF04695.13 CDJ68549.1 - 0.024 15.3 4.1 0.024 15.3 4.1 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Roughex PF06020.11 CDJ68549.1 - 0.029 13.5 5.2 0.049 12.7 5.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein RAP1 PF07218.11 CDJ68549.1 - 0.03 12.6 6.5 0.029 12.7 6.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Plasmodium_Vir PF05795.11 CDJ68549.1 - 0.032 13.7 4.6 0.039 13.4 4.6 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4834 PF16118.5 CDJ68549.1 - 0.033 15.1 2.3 0.033 15.1 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SARAF PF06682.12 CDJ68549.1 - 0.033 13.8 13.8 0.042 13.5 13.8 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SPX PF03105.19 CDJ68549.1 - 0.038 13.9 15.2 0.043 13.7 15.2 1.1 1 0 0 1 1 1 0 SPX domain baeRF_family10 PF18854.1 CDJ68549.1 - 0.073 13.3 5.3 0.13 12.5 5.3 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 Senescence_reg PF04520.13 CDJ68549.1 - 0.15 12.9 7.5 0.2 12.5 7.5 1.2 1 0 0 1 1 1 0 Senescence regulator Presenilin PF01080.17 CDJ68549.1 - 0.24 10.1 9.0 0.29 9.8 9.0 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 CDJ68549.1 - 0.34 9.7 3.5 0.42 9.4 3.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_S64 PF08192.11 CDJ68549.1 - 0.37 9.2 10.6 0.42 9.0 10.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 CDJ68549.1 - 0.92 6.5 13.7 0.98 6.5 13.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Secretin_N_2 PF07655.13 CDJ68549.1 - 1.1 9.8 16.6 1.5 9.4 10.1 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain CCDC24 PF15669.5 CDJ68549.1 - 3.6 7.4 17.5 11 5.9 17.5 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF1645 PF07816.11 CDJ68549.1 - 6.1 7.4 23.7 13 6.3 23.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) EFTUD2 PF16004.5 CDJ68550.1 - 0.32 11.6 17.9 2.3 8.8 3.5 2.2 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus SR-25 PF10500.9 CDJ68550.1 - 0.32 10.6 30.4 0.6 9.7 11.2 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein IHABP4_N PF16174.5 CDJ68550.1 - 0.5 11.0 30.3 1.4 9.5 15.2 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Roughex PF06020.11 CDJ68550.1 - 0.5 9.4 20.7 0.99 8.4 9.9 2.2 2 0 0 2 2 2 0 Drosophila roughex protein SprA-related PF12118.8 CDJ68550.1 - 0.67 9.0 46.5 0.24 10.5 24.5 2.2 2 0 0 2 2 2 0 SprA-related family DUF4770 PF15994.5 CDJ68550.1 - 0.83 9.9 16.1 1.7 8.9 7.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF4179 PF13786.6 CDJ68550.1 - 1 9.9 13.2 1.2 9.6 0.7 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) CTNNB1_binding PF08347.11 CDJ68550.1 - 2.2 8.4 16.3 4 7.6 3.2 2.2 2 0 0 2 2 2 0 N-terminal CTNNB1 binding TOM13 PF08219.11 CDJ68550.1 - 2.3 8.3 4.2 4.4 7.3 0.6 2.5 2 0 0 2 2 2 0 Outer membrane protein TOM13 RuvC_III PF18541.1 CDJ68550.1 - 2.8 7.8 14.3 5.4 6.9 1.2 2.3 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 Hamartin PF04388.12 CDJ68550.1 - 3 6.4 23.7 3.5 6.2 23.7 1.1 1 0 0 1 1 1 0 Hamartin protein DUF3886 PF13025.6 CDJ68550.1 - 3.1 8.1 22.9 4.7 7.5 10.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) EIIBC-GUT_N PF03612.14 CDJ68550.1 - 3.4 7.4 17.3 1.7 8.3 6.8 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus PCYCGC PF13798.6 CDJ68550.1 - 3.8 7.3 11.0 3.8 7.3 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif EIF4E-T PF10477.9 CDJ68550.1 - 3.9 6.2 28.5 5.2 5.8 28.5 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E WASH-7_C PF14746.6 CDJ68550.1 - 4.1 7.1 13.8 2.3 7.9 6.7 2.4 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal DUF5421 PF17458.2 CDJ68550.1 - 4.7 6.5 20.6 0.66 9.3 7.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5421) Pex14_N PF04695.13 CDJ68550.1 - 4.8 7.8 49.4 1.2 9.7 15.3 2.3 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_Mycoplasma PF07672.13 CDJ68550.1 - 6.6 5.9 4.9 4.8 6.4 0.3 2.1 2 0 0 2 2 2 0 Mycoplasma MFS transporter FPN1 PF06963.12 CDJ68550.1 - 6.9 5.1 9.8 1.3 7.5 2.1 2.1 2 0 0 2 2 2 0 Ferroportin1 (FPN1) TFB6 PF17110.5 CDJ68550.1 - 8 6.2 8.1 5.7 6.7 3.3 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH TFIIA PF03153.13 CDJ68551.1 - 0.17 11.8 25.8 0.18 11.7 25.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ68553.1 - 0.28 10.7 24.7 0.43 10.1 24.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SOBP PF15279.6 CDJ68553.1 - 1 9.9 24.7 0.21 12.2 20.5 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein V_ATPase_I PF01496.19 CDJ68553.1 - 1.7 6.4 16.8 2.2 6.1 16.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAJIN PF15077.6 CDJ68553.1 - 1.8 8.3 18.7 1.6 8.4 16.3 2.0 2 0 0 2 2 2 0 Membrane-anchored junction protein CDK5_activator PF03261.15 CDJ68553.1 - 2 7.9 20.8 2.9 7.4 20.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein LMBR1 PF04791.16 CDJ68553.1 - 2.4 7.0 11.1 3.3 6.5 11.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MMR1 PF08505.10 CDJ68553.1 - 8.4 6.6 22.0 16 5.7 22.0 1.6 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SR-25 PF10500.9 CDJ68554.1 - 9.2e-05 22.2 24.5 0.00093 18.9 2.9 5.3 4 2 0 4 4 4 2 Nuclear RNA-splicing-associated protein AP2 PF00847.20 CDJ68554.1 - 0.00017 21.7 0.1 0.00017 21.7 0.1 3.8 5 0 0 5 5 5 1 AP2 domain Exostosin PF03016.15 CDJ68554.1 - 0.59 9.3 6.0 0.31 10.2 3.1 1.9 2 0 0 2 2 2 0 Exostosin family SUR7 PF06687.12 CDJ68555.1 - 0.032 13.8 0.7 0.048 13.3 0.7 1.2 1 0 0 1 1 1 0 SUR7/PalI family Wzy_C PF04932.15 CDJ68555.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 O-Antigen ligase HMA PF00403.26 CDJ68556.1 - 8.2e-08 32.6 0.7 8e-07 29.4 0.0 2.6 2 1 1 3 3 3 1 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 CDJ68557.1 - 4.9e-18 65.3 6.9 1.4e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 CDJ68557.1 - 0.047 14.0 0.1 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ABC2_membrane_2 PF12679.7 CDJ68557.1 - 1.5 8.1 4.5 4.4 6.5 2.7 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Hydrolase PF00702.26 CDJ68558.1 - 2.9e-15 57.1 0.0 1.2e-12 48.6 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ68558.1 - 0.0038 17.0 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase SLATT_1 PF18181.1 CDJ68558.1 - 1.5 8.7 6.6 0.23 11.4 1.4 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Bacillus_PapR PF05968.11 CDJ68558.1 - 3.1 7.8 5.5 20 5.2 0.5 2.6 2 0 0 2 2 2 0 Bacillus PapR protein ArfGap PF01412.18 CDJ68559.1 - 1.3e-10 41.4 0.5 4.4e-08 33.2 0.0 3.1 3 1 1 4 4 4 2 Putative GTPase activating protein for Arf SUIM_assoc PF16619.5 CDJ68559.1 - 0.2 11.8 11.8 0.68 10.0 5.1 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CIAPIN1 PF05093.13 CDJ68559.1 - 0.34 11.4 2.2 5 7.7 0.1 2.4 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis ABC2_membrane_2 PF12679.7 CDJ68559.1 - 0.77 9.0 3.5 1.3 8.2 3.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein MccV PF17508.2 CDJ68559.1 - 4.9 7.8 8.2 5.1 7.7 6.1 2.1 2 0 0 2 2 2 0 Microcin V bacteriocin Spt20 PF12090.8 CDJ68559.1 - 8.5 5.9 16.4 2.1 7.9 7.2 2.1 2 0 0 2 2 2 0 Spt20 family Roughex PF06020.11 CDJ68560.1 - 1.1 8.2 10.7 3.4 6.7 10.7 1.7 1 1 0 1 1 1 0 Drosophila roughex protein Peroxin-3 PF04882.12 CDJ68561.1 - 0.0014 17.7 11.1 0.0014 17.7 11.1 6.8 5 2 1 6 6 6 1 Peroxin-3 IMUP PF15761.5 CDJ68561.1 - 0.0066 17.1 4.1 0.0066 17.1 4.1 9.3 4 2 4 8 8 8 1 Immortalisation up-regulated protein DDT PF02791.17 CDJ68561.1 - 0.36 11.2 2.4 7.6 6.9 2.4 2.7 1 1 0 1 1 1 0 DDT domain FAM76 PF16046.5 CDJ68562.1 - 3.4 6.9 40.7 0.18 11.1 17.2 2.4 2 0 0 2 2 2 0 FAM76 protein SNARE_assoc PF09335.11 CDJ68563.1 - 8.4e-18 65.0 7.6 8.4e-18 65.0 7.6 2.6 3 1 0 3 3 3 1 SNARE associated Golgi protein DUF2722 PF10846.8 CDJ68563.1 - 8.4e-05 21.7 2.0 9.6e-05 21.5 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) CbtA PF09490.10 CDJ68563.1 - 0.00019 21.3 4.1 0.0039 17.0 0.7 2.6 2 0 0 2 2 2 1 Probable cobalt transporter subunit (CbtA) Pex14_N PF04695.13 CDJ68563.1 - 0.012 16.3 0.8 0.012 16.3 0.8 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2207 PF09972.9 CDJ68563.1 - 0.032 13.0 0.0 0.032 13.0 0.0 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2407_C PF13373.6 CDJ68563.1 - 0.037 14.2 3.2 0.19 11.9 2.7 2.6 1 1 0 1 1 1 0 DUF2407 C-terminal domain Rax2 PF12768.7 CDJ68563.1 - 0.071 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity AIF_C PF14721.6 CDJ68563.1 - 0.072 13.4 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3464 PF11947.8 CDJ68563.1 - 0.089 12.5 0.4 0.65 9.7 0.1 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 PvlArgDC PF01862.16 CDJ68563.1 - 0.097 12.5 0.1 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Med15 PF09606.10 CDJ68563.1 - 0.15 10.7 12.1 0.19 10.3 12.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal K_channel_TID PF07941.11 CDJ68563.1 - 0.2 12.1 6.9 0.43 11.1 6.9 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain TetR_C_11 PF16859.5 CDJ68563.1 - 0.53 10.6 4.8 0.39 11.0 1.5 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF2967 PF11179.8 CDJ68563.1 - 0.7 7.9 8.2 0.93 7.5 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) CNDH2_M PF16869.5 CDJ68563.1 - 0.75 10.5 4.5 1.3 9.7 4.5 1.3 1 0 0 1 1 1 0 PF16858 Spt20 PF12090.8 CDJ68563.1 - 0.82 9.2 18.9 1.2 8.8 18.9 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ68563.1 - 1.3 8.9 14.6 1.8 8.5 14.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1674 PF07896.12 CDJ68565.1 - 1.6 9.3 0.0 1.6 9.3 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1674) Histone PF00125.24 CDJ68566.1 - 2e-06 28.2 0.3 2e-06 28.2 0.3 2.6 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDJ68566.1 - 1.4e-05 25.3 0.6 4e-05 23.8 0.6 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2722 PF10846.8 CDJ68566.1 - 0.00016 20.8 3.6 0.00016 20.8 3.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF4667 PF15700.5 CDJ68566.1 - 0.002 18.3 15.3 0.025 14.7 2.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ68566.1 - 0.0068 16.5 21.9 0.0094 16.0 21.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ68566.1 - 0.01 15.4 28.9 0.037 13.6 9.1 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF31 PF01732.16 CDJ68566.1 - 0.054 13.0 0.2 0.082 12.4 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Rxt3 PF08642.10 CDJ68566.1 - 0.055 14.2 0.4 0.055 14.2 0.4 2.2 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 Pap_E4 PF02711.14 CDJ68566.1 - 0.057 14.4 7.7 5.2 8.1 1.0 3.1 3 0 0 3 3 3 0 E4 protein DUF4834 PF16118.5 CDJ68566.1 - 0.068 14.1 0.9 0.068 14.1 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3446 PF11928.8 CDJ68566.1 - 0.17 12.2 28.9 1.5 9.2 12.4 3.4 3 0 0 3 3 3 0 Early growth response N-terminal domain SAPIS-gp6 PF16722.5 CDJ68566.1 - 0.17 12.3 7.8 0.41 11.1 7.8 1.7 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus OATP PF03137.20 CDJ68566.1 - 0.24 9.6 0.4 0.44 8.8 0.4 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4598 PF15370.6 CDJ68566.1 - 0.39 11.2 11.5 0.22 12.0 0.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4598) Hep_59 PF07052.11 CDJ68566.1 - 1.5 9.6 11.0 0.47 11.2 2.4 3.1 3 0 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 DUF1266 PF06889.11 CDJ68566.1 - 1.9 8.5 7.8 1.4 8.9 5.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) DivIC PF04977.15 CDJ68566.1 - 3.8 7.3 11.8 9.5 6.1 11.8 1.7 1 0 0 1 1 1 0 Septum formation initiator Arm PF00514.23 CDJ68568.1 - 6.4e-89 289.6 19.7 1.5e-14 53.5 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CDJ68568.1 - 2.1e-25 88.7 8.0 5.5e-09 36.3 0.1 6.8 5 2 0 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 CDJ68568.1 - 2e-17 63.3 4.6 4.5e-07 30.2 0.0 5.2 2 2 1 4 4 4 3 HEAT repeats Arm_3 PF16186.5 CDJ68568.1 - 2.4e-13 49.4 0.0 7.2e-12 44.7 0.0 2.8 3 0 0 3 3 3 1 Atypical Arm repeat HEAT PF02985.22 CDJ68568.1 - 1.8e-12 46.4 6.8 5.9e-05 23.0 0.0 7.2 8 1 1 9 9 8 3 HEAT repeat IBB PF01749.20 CDJ68568.1 - 8.8e-11 42.1 1.5 8.7e-09 35.7 2.5 2.9 3 0 0 3 3 3 1 Importin beta binding domain V-ATPase_H_C PF11698.8 CDJ68568.1 - 8.1e-05 22.7 0.0 0.24 11.5 0.0 3.8 3 1 2 5 5 5 2 V-ATPase subunit H Adaptin_N PF01602.20 CDJ68568.1 - 0.00013 20.7 0.0 0.053 12.1 0.0 3.0 2 1 1 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.6 CDJ68568.1 - 0.002 18.4 0.1 1.2 9.5 0.0 4.1 4 2 2 6 6 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 CDJ68568.1 - 0.002 17.6 0.0 0.75 9.2 0.0 3.0 1 1 2 3 3 3 2 Armadillo-like HEAT_PBS PF03130.16 CDJ68568.1 - 0.013 16.1 9.2 0.11 13.3 0.0 6.2 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 CDJ68568.1 - 0.031 14.3 0.0 1.1 9.4 0.0 2.8 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_N PF03224.14 CDJ68568.1 - 0.19 11.0 0.0 0.74 9.0 0.0 1.9 3 0 0 3 3 3 0 V-ATPase subunit H Pkinase PF00069.25 CDJ68569.1 - 1.1e-54 185.6 5.3 1.1e-47 162.6 0.0 3.2 3 0 0 3 3 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ68569.1 - 2.1e-17 63.3 4.7 8.9e-15 54.7 0.0 3.1 3 1 1 4 4 4 2 Protein tyrosine kinase EF-hand_7 PF13499.6 CDJ68569.1 - 1.3e-16 60.8 0.4 2.1e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ68569.1 - 7.5e-15 53.3 1.1 0.0045 16.4 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDJ68569.1 - 1.8e-11 43.0 0.7 0.0033 17.2 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CDJ68569.1 - 1.7e-09 37.4 0.6 0.0014 18.4 0.0 3.6 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CDJ68569.1 - 0.026 14.0 0.3 8.3 6.1 0.0 3.3 3 0 0 3 3 3 0 EF hand EF-hand_9 PF14658.6 CDJ68569.1 - 0.17 12.2 0.0 8.2 6.8 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain Choline_kinase PF01633.20 CDJ68569.1 - 0.2 11.2 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase SPARC_Ca_bdg PF10591.9 CDJ68569.1 - 0.31 11.4 0.0 0.31 11.4 0.0 3.8 2 2 1 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region PAT1 PF09770.9 CDJ68569.1 - 2.5 6.2 61.0 0.025 12.9 50.5 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.27 CDJ68570.1 - 5.9e-10 38.9 0.0 0.00046 20.0 0.0 2.8 2 0 0 2 2 2 2 Mitochondrial carrier protein SPX PF03105.19 CDJ68570.1 - 0.18 11.7 11.8 1.4 8.8 11.8 2.0 1 1 0 1 1 1 0 SPX domain SpoIIIAH PF12685.7 CDJ68570.1 - 0.39 10.5 9.3 80 3.0 12.2 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Peptidase_S64 PF08192.11 CDJ68570.1 - 1.6 7.1 8.1 0.068 11.7 0.8 1.8 2 0 0 2 2 2 0 Peptidase family S64 TCP PF03634.13 CDJ68570.1 - 3.5 8.2 15.0 6.4 7.3 9.9 2.2 2 0 0 2 2 2 0 TCP family transcription factor NAM-associated PF14303.6 CDJ68570.1 - 5.2 7.8 21.0 0.2 12.4 8.7 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Spt20 PF12090.8 CDJ68571.1 - 0.0047 16.6 6.1 0.0047 16.6 6.1 4.2 3 1 0 3 3 3 2 Spt20 family SUIM_assoc PF16619.5 CDJ68571.1 - 0.0051 16.9 3.9 0.0051 16.9 3.9 5.8 4 3 1 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ68572.1 - 2.8e-05 24.5 6.4 2.8e-05 24.5 6.4 5.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF4148 PF13663.6 CDJ68572.1 - 0.21 11.8 0.2 0.21 11.8 0.2 4.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4148) Parvo_coat_N PF08398.10 CDJ68572.1 - 7.7 6.8 10.3 0.32 11.2 1.0 3.3 2 0 0 2 2 2 0 Parvovirus coat protein VP1 PMI_typeI PF01238.21 CDJ68573.1 - 4.6e-05 22.8 0.2 4.6e-05 22.8 0.2 2.1 2 0 0 2 2 2 1 Phosphomannose isomerase type I Peptidase_S64 PF08192.11 CDJ68573.1 - 0.016 13.8 10.5 0.021 13.4 10.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 EMC3_TMCO1 PF01956.16 CDJ68573.1 - 0.14 11.9 10.2 0.57 9.9 5.3 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SpoVR PF04293.13 CDJ68573.1 - 0.21 10.3 7.5 0.026 13.2 1.2 2.0 2 0 0 2 2 2 0 SpoVR like protein Mit_KHE1 PF10173.9 CDJ68573.1 - 0.35 10.9 5.9 1.4 9.0 0.5 2.3 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related GET2 PF08690.10 CDJ68573.1 - 0.63 9.6 27.4 0.041 13.6 12.5 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 SpoIIP PF07454.11 CDJ68573.1 - 0.69 9.3 7.9 6.6 6.1 0.1 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RNR_Alpha PF17975.1 CDJ68573.1 - 0.83 10.2 4.2 4 8.0 0.3 2.2 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain CCSAP PF15748.5 CDJ68573.1 - 0.85 9.7 22.0 0.28 11.3 11.8 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated MCU PF04678.13 CDJ68573.1 - 0.87 9.7 7.5 1.5 8.9 0.7 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Med15 PF09606.10 CDJ68573.1 - 2.9 6.5 41.6 3.1 6.4 14.7 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ68573.1 - 3.1 7.7 51.0 0.0098 15.9 17.1 2.1 1 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 CDJ68573.1 - 3.2 7.3 23.9 0.18 11.4 1.1 3.0 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis GTA_holin_3TM PF11351.8 CDJ68573.1 - 3.8 8.1 12.5 11 6.6 2.8 2.4 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release TOM13 PF08219.11 CDJ68573.1 - 5.5 7.0 7.8 5.3 7.1 0.1 3.2 3 0 0 3 3 3 0 Outer membrane protein TOM13 RNA_pol_Rbc25 PF08292.12 CDJ68573.1 - 7.1 6.9 11.5 3.5 7.9 3.4 2.5 2 1 0 2 2 2 0 RNA polymerase III subunit Rpc25 SPT16 PF08644.11 CDJ68573.1 - 7.8 6.7 11.4 4.8 7.3 4.5 2.3 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) AAA_23 PF13476.6 CDJ68573.1 - 9.8 6.6 23.3 0.22 12.0 4.5 2.1 2 0 0 2 2 2 0 AAA domain MCM_N PF14551.6 CDJ68574.1 - 3.6e-07 30.7 0.0 8.6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain ASXH PF13919.6 CDJ68574.1 - 0.0069 16.4 5.1 0.014 15.5 5.1 1.4 1 0 0 1 1 1 1 Asx homology domain Presenilin PF01080.17 CDJ68574.1 - 0.092 11.5 0.1 0.085 11.6 0.1 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_60s PF00428.19 CDJ68574.1 - 0.3 11.7 16.9 0.37 11.4 7.6 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ68574.1 - 0.81 9.6 17.7 1.2 9.1 17.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ68574.1 - 7.2 6.5 7.2 11 5.9 7.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Senescence_reg PF04520.13 CDJ68577.1 - 1.9 9.3 13.2 2.2 9.1 13.2 1.1 1 0 0 1 1 1 0 Senescence regulator Silic_transp PF03842.13 CDJ68577.1 - 2.1 6.5 5.4 2.4 6.4 5.4 1.0 1 0 0 1 1 1 0 Silicon transporter RskA PF10099.9 CDJ68578.1 - 0.077 13.3 29.5 0.13 12.5 29.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Synaptobrevin PF00957.21 CDJ68579.1 - 2.5e-14 52.8 0.5 5.7e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 CDJ68579.1 - 6.1e-14 51.8 0.0 1.2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2284 PF10050.9 CDJ68579.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) HMG_box PF00505.19 CDJ68580.1 - 1.4e-19 70.3 2.8 2.1e-19 69.7 2.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ68580.1 - 4.5e-11 43.2 3.0 6.4e-11 42.7 3.0 1.3 1 0 0 1 1 1 1 HMG-box domain MlaC PF05494.12 CDJ68580.1 - 0.0096 15.7 1.5 0.013 15.3 1.5 1.2 1 0 0 1 1 1 1 MlaC protein YABBY PF04690.13 CDJ68580.1 - 0.022 15.3 2.8 0.033 14.7 2.8 1.5 1 1 0 1 1 1 0 YABBY protein Sporozoite_P67 PF05642.11 CDJ68580.1 - 0.12 10.4 6.0 0.13 10.3 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF508 PF04370.12 CDJ68580.1 - 0.47 10.2 5.5 0.68 9.7 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) GET2 PF08690.10 CDJ68580.1 - 1.3 8.7 7.7 1.3 8.6 7.7 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 NAM-associated PF14303.6 CDJ68580.1 - 1.6 9.4 10.5 2.2 9.0 10.5 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RAP1 PF07218.11 CDJ68580.1 - 3 6.0 9.5 2.8 6.1 9.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apc15p PF05841.11 CDJ68580.1 - 9.5 7.0 11.0 2.5 8.9 0.2 2.2 1 1 1 2 2 2 0 Apc15p protein TFIIA PF03153.13 CDJ68582.1 - 0.12 12.3 26.4 0.29 11.1 26.4 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ68582.1 - 0.87 9.1 7.3 1.5 8.3 7.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.13 CDJ68582.1 - 4.7 6.9 5.6 6.6 6.4 5.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Sin_N PF04801.13 CDJ68582.1 - 6.2 5.9 15.2 9 5.4 15.2 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region AUX_IAA PF02309.16 CDJ68582.1 - 7.8 6.3 8.0 31 4.3 0.0 2.6 2 1 0 2 2 2 0 AUX/IAA family Med25_VWA PF11265.8 CDJ68583.1 - 0.0098 15.7 0.4 0.013 15.3 0.4 1.2 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A DUF3947 PF13135.6 CDJ68583.1 - 0.035 14.3 5.3 0.05 13.8 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) TFIIA PF03153.13 CDJ68583.1 - 0.05 13.6 10.6 0.051 13.6 10.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ68583.1 - 0.089 12.8 2.7 0.11 12.4 2.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ68583.1 - 0.45 9.2 4.0 0.42 9.3 4.0 1.1 1 0 0 1 1 1 0 Presenilin Chon_Sulph_att PF06566.11 CDJ68583.1 - 0.75 9.6 6.2 0.9 9.4 6.2 1.1 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain Podoplanin PF05808.11 CDJ68583.1 - 1.4 9.0 4.5 2 8.5 4.5 1.2 1 0 0 1 1 1 0 Podoplanin DUF4569 PF15133.6 CDJ68583.1 - 1.9 8.1 6.6 2.2 7.9 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) SUIM_assoc PF16619.5 CDJ68583.1 - 3.3 7.8 13.7 5.1 7.3 13.7 1.5 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 IHABP4_N PF16174.5 CDJ68583.1 - 4.5 7.8 11.4 7.7 7.1 11.4 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Dehydrin PF00257.19 CDJ68583.1 - 6.7 7.2 10.5 9.7 6.7 10.5 1.2 1 0 0 1 1 1 0 Dehydrin DUF966 PF06136.13 CDJ68583.1 - 6.8 6.3 7.6 7.6 6.1 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Spore_coat_CotO PF14153.6 CDJ68583.1 - 7.4 6.5 15.4 9.5 6.1 15.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO IMUP PF15761.5 CDJ68584.1 - 0.28 11.9 14.6 0.46 11.2 14.6 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ68584.1 - 0.45 10.1 19.0 0.59 9.7 19.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MFS_1 PF07690.16 CDJ68585.1 - 7.1e-14 51.5 34.3 6.1e-10 38.6 3.5 3.6 3 1 1 4 4 3 2 Major Facilitator Superfamily RskA PF10099.9 CDJ68585.1 - 2e-05 25.0 4.2 2e-05 25.0 4.2 7.0 2 1 1 4 4 3 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ68585.1 - 0.0099 16.8 2.4 3.7 8.6 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4834) Conotoxin PF02950.17 CDJ68585.1 - 0.085 13.9 4.8 0.3 12.1 0.0 3.4 3 0 0 3 3 3 0 Conotoxin EphA2_TM PF14575.6 CDJ68585.1 - 0.33 11.9 4.1 48 4.9 0.0 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4752 PF15944.5 CDJ68585.1 - 0.42 10.7 3.6 4.5 7.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) V_ATPase_I PF01496.19 CDJ68585.1 - 0.54 8.1 2.0 0.62 7.9 0.2 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TMEM51 PF15345.6 CDJ68585.1 - 4.2 7.1 15.9 1.5 8.6 0.1 3.8 4 0 0 4 4 4 0 Transmembrane protein 51 DUF2722 PF10846.8 CDJ68585.1 - 5.2 5.9 20.7 0.18 10.7 2.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) ANAPC_CDC26 PF10471.9 CDJ68585.1 - 6.2 7.7 33.1 1.1 10.2 5.6 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 FAM176 PF14851.6 CDJ68585.1 - 8.2 6.1 6.2 6.4 6.4 0.1 2.8 3 0 0 3 3 3 0 FAM176 family Spt20 PF12090.8 CDJ68587.1 - 0.0084 15.7 9.9 0.016 14.8 0.8 2.2 2 0 0 2 2 2 2 Spt20 family SNARE_assoc PF09335.11 CDJ68587.1 - 0.033 14.7 0.5 0.13 12.8 0.5 2.0 1 0 0 1 1 1 0 SNARE associated Golgi protein SUIM_assoc PF16619.5 CDJ68587.1 - 0.27 11.3 20.1 0.055 13.5 1.4 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4667 PF15700.5 CDJ68587.1 - 1 9.4 23.9 0.26 11.4 7.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) PAN_4 PF14295.6 CDJ68588.1 - 7.6e-27 93.0 17.2 1.9e-09 37.3 0.3 4.6 4 0 0 4 4 4 4 PAN domain MID_MedPIWI PF18296.1 CDJ68588.1 - 0.022 14.6 17.8 0.094 12.5 3.4 2.2 2 0 0 2 2 2 0 MID domain of medPIWI Filament_head PF04732.14 CDJ68588.1 - 0.031 15.1 24.3 0.031 15.1 24.3 4.0 4 0 0 4 4 4 0 Intermediate filament head (DNA binding) region Tim54 PF11711.8 CDJ68588.1 - 0.097 11.4 4.5 1.8 7.3 4.0 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SpoIIIAH PF12685.7 CDJ68588.1 - 0.88 9.4 13.4 2.6 7.8 0.8 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Sec62 PF03839.16 CDJ68588.1 - 0.92 9.0 4.4 18 4.7 4.1 2.6 3 0 0 3 3 3 0 Translocation protein Sec62 Roughex PF06020.11 CDJ68588.1 - 0.95 8.5 4.8 1.7 7.6 4.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein PRCC PF10253.9 CDJ68588.1 - 1.8 9.3 22.6 0.11 13.3 6.7 2.4 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting PAN_3 PF08277.12 CDJ68588.1 - 2.9 7.8 12.6 5.1 7.0 1.0 4.0 3 0 0 3 3 3 0 PAN-like domain TLP-20 PF06088.11 CDJ68588.1 - 3.8 7.4 7.0 4 7.3 2.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) EPL1 PF10513.9 CDJ68588.1 - 4.7 7.6 12.0 4.7 7.6 7.1 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Striatin PF08232.12 CDJ68588.1 - 5.7 7.5 11.9 22 5.6 0.1 2.2 2 0 0 2 2 2 0 Striatin family TCP PF03634.13 CDJ68588.1 - 8 7.0 27.8 6.7 7.3 15.0 2.2 2 0 0 2 2 2 0 TCP family transcription factor SOG2 PF10428.9 CDJ68589.1 - 0.073 12.3 2.6 0.095 11.9 2.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DHHC PF01529.20 CDJ68589.1 - 0.19 11.9 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF4834 PF16118.5 CDJ68590.1 - 0.071 14.1 0.9 0.071 14.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4710 PF15828.5 CDJ68590.1 - 0.15 12.2 6.0 0.2 11.8 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Conotoxin PF02950.17 CDJ68590.1 - 0.66 11.0 3.3 1 10.4 3.3 1.3 1 0 0 1 1 1 0 Conotoxin Spt20 PF12090.8 CDJ68590.1 - 0.66 9.5 13.4 0.71 9.4 13.4 1.0 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 CDJ68590.1 - 1.1 8.2 9.8 1.2 8.1 9.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ68590.1 - 1.3 7.7 4.7 1.3 7.7 4.7 1.0 1 0 0 1 1 1 0 Presenilin Baculo_PP31 PF05311.11 CDJ68590.1 - 5.8 6.3 7.4 6.3 6.2 7.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Androgen_recep PF02166.16 CDJ68590.1 - 8.6 5.1 22.1 11 4.8 22.1 1.1 1 0 0 1 1 1 0 Androgen receptor BRF1 PF07741.13 CDJ68590.1 - 10 6.6 11.3 13 6.1 11.3 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain FAIM1 PF06905.13 CDJ68592.1 - 0.00098 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) eIF-3_zeta PF05091.12 CDJ68592.1 - 0.12 11.3 1.3 0.18 10.8 1.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ68592.1 - 0.28 11.1 24.0 0.031 14.3 16.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ68592.1 - 3.4 6.3 3.7 4.9 5.8 3.7 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ68592.1 - 5.3 5.2 12.6 9.1 4.4 12.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SUIM_assoc PF16619.5 CDJ68592.1 - 6.2 7.0 25.5 5.9 7.0 10.4 3.8 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RCC1 PF00415.18 CDJ68594.1 - 1.4e-06 28.8 5.9 0.00051 20.6 0.1 3.4 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ68594.1 - 5e-06 26.2 2.0 2.6e-05 23.9 0.4 2.5 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat DUF2722 PF10846.8 CDJ68594.1 - 0.0024 16.9 4.0 0.0024 16.9 4.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ68594.1 - 0.28 11.1 8.4 0.46 10.4 1.7 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3464 PF11947.8 CDJ68594.1 - 0.97 9.2 5.6 2.3 8.0 0.6 2.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 RskA PF10099.9 CDJ68594.1 - 1.3 9.3 23.1 0.09 13.1 11.8 2.8 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Ras PF00071.22 CDJ68595.1 - 1.1e-40 138.9 0.1 1.3e-40 138.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ68595.1 - 1.2e-19 70.7 0.3 3e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ68595.1 - 3.3e-08 33.2 0.0 4.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ68595.1 - 6.6e-08 32.3 0.0 1.2e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ68595.1 - 0.013 15.4 0.1 0.022 14.6 0.1 1.4 1 1 0 1 1 1 0 RsgA GTPase Phage_tail_S PF05069.13 CDJ68595.1 - 0.025 14.4 2.0 0.046 13.6 2.0 1.3 1 0 0 1 1 1 0 Phage virion morphogenesis family PhaC_N PF07167.13 CDJ68595.1 - 0.029 14.0 0.4 0.038 13.6 0.4 1.2 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Gtr1_RagA PF04670.12 CDJ68595.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TFIIA PF03153.13 CDJ68595.1 - 2.7 7.9 9.5 3.1 7.7 9.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 CDJ68596.1 - 3.1e-60 199.9 1.7 1.1e-18 66.8 0.1 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CDJ68596.1 - 1.3e-25 89.3 1.4 1.3e-25 89.3 1.4 3.8 5 0 0 5 5 5 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 CDJ68596.1 - 0.011 15.8 0.0 4.9 7.3 0.0 3.9 3 1 0 3 3 3 0 RNA recognition motif DUF2722 PF10846.8 CDJ68596.1 - 0.066 12.2 0.1 0.066 12.2 0.1 7.9 3 2 2 5 5 5 0 Protein of unknown function (DUF2722) Glycolytic PF00274.19 CDJ68597.1 - 1.4e-152 507.5 0.0 2.7e-152 506.5 0.0 1.4 1 1 0 1 1 1 1 Fructose-bisphosphate aldolase class-I LEP503 PF15221.6 CDJ68597.1 - 0.041 14.2 0.2 0.1 13.0 0.2 1.7 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 DUF179 PF02622.15 CDJ68598.1 - 1e-08 35.3 0.2 3.3e-05 23.9 0.1 2.7 2 0 0 2 2 2 2 Uncharacterized ACR, COG1678 DUF4564 PF15169.6 CDJ68598.1 - 3.4 7.4 5.7 0.99 9.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4564) RRM_1 PF00076.22 CDJ68599.1 - 0.0011 18.7 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUIM_assoc PF16619.5 CDJ68599.1 - 0.0079 16.2 12.5 0.0091 16.0 2.6 2.4 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 RRM_7 PF16367.5 CDJ68599.1 - 0.035 14.2 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif DUF3138 PF11336.8 CDJ68599.1 - 0.054 12.1 6.9 0.044 12.4 5.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) RskA PF10099.9 CDJ68599.1 - 0.39 11.0 17.1 0.24 11.7 8.4 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DivIC PF04977.15 CDJ68599.1 - 3.4 7.5 16.8 0.73 9.6 2.7 2.4 2 0 0 2 2 2 0 Septum formation initiator Cwf_Cwc_15 PF04889.12 CDJ68599.1 - 6 6.5 12.0 0.73 9.5 4.5 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2924 PF11149.8 CDJ68599.1 - 6.4 7.2 8.7 19 5.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) TFIIA PF03153.13 CDJ68600.1 - 0.9 9.5 31.3 0.69 9.8 5.9 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 CDJ68601.1 - 0.001 19.2 8.0 0.0012 19.0 8.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1645 PF07816.11 CDJ68601.1 - 0.0027 18.3 5.0 0.0027 18.3 5.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1645) Lin-8 PF03353.15 CDJ68601.1 - 0.044 13.3 7.2 0.069 12.7 7.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 CDJ68601.1 - 0.085 10.0 4.4 0.12 9.5 4.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2722 PF10846.8 CDJ68601.1 - 0.13 11.2 12.5 0.2 10.6 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TMEM171 PF15471.6 CDJ68601.1 - 0.19 10.7 4.3 0.29 10.1 4.3 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Sporozoite_P67 PF05642.11 CDJ68601.1 - 0.31 9.1 2.3 0.4 8.7 2.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Suf PF05843.14 CDJ68601.1 - 0.39 10.7 4.4 0.55 10.2 4.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ68601.1 - 0.46 9.2 3.1 0.67 8.7 3.1 1.2 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 CDJ68601.1 - 0.62 9.9 6.9 0.94 9.3 6.9 1.2 1 0 0 1 1 1 0 SPX domain CDK2AP PF09806.9 CDJ68601.1 - 0.71 9.9 8.9 0.058 13.5 3.3 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Topoisom_bac PF01131.20 CDJ68603.1 - 6.7e-103 344.9 0.0 8.3e-103 344.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Cript PF10235.9 CDJ68603.1 - 0.16 12.6 0.9 0.37 11.4 0.1 2.1 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT GHL10 PF02638.15 CDJ68603.1 - 0.2 10.7 0.1 0.31 10.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 SUIM_assoc PF16619.5 CDJ68603.1 - 0.43 10.7 4.2 1.4 9.1 3.8 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 EFTUD2 PF16004.5 CDJ68605.1 - 8e-31 107.2 0.5 8e-31 107.2 0.5 3.1 3 0 0 3 3 3 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus GTP_EFTU PF00009.27 CDJ68605.1 - 1.5e-30 106.2 0.0 1.1e-28 100.1 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CDJ68605.1 - 2.4e-22 78.7 0.0 5.6e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CDJ68605.1 - 1.8e-19 69.7 0.0 4.2e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 CDJ68605.1 - 0.00018 21.9 0.0 0.00047 20.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ68605.1 - 0.1 12.7 0.0 0.58 10.3 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CDJ68605.1 - 0.11 12.6 0.0 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain PAP1 PF08601.10 CDJ68605.1 - 1.5 8.5 9.8 3 7.5 6.4 2.3 2 0 0 2 2 2 0 Transcription factor PAP1 Secretin_N_2 PF07655.13 CDJ68605.1 - 3.1 8.4 16.3 12 6.5 9.5 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Aminotran_3 PF00202.21 CDJ68606.1 - 1.4e-119 399.4 0.0 1.7e-119 399.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CDJ68606.1 - 0.0082 15.4 0.0 0.017 14.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II MHC_I PF00129.18 CDJ68606.1 - 0.095 12.3 0.0 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 DnaJ PF00226.31 CDJ68607.1 - 6.4e-10 39.0 0.1 2e-09 37.5 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain KH_1 PF00013.29 CDJ68608.1 - 2.4e-41 139.4 0.1 1.6e-11 43.8 0.2 5.9 6 0 0 6 6 6 4 KH domain KH_2 PF07650.17 CDJ68608.1 - 0.013 15.3 0.0 1.7 8.6 0.0 3.1 3 0 0 3 3 3 0 KH domain Pkinase PF00069.25 CDJ68609.1 - 1.5e-24 86.8 0.0 6.1e-24 84.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ68609.1 - 3.4e-23 82.4 0.0 4.9e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ68609.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ68609.1 - 0.0078 15.6 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 CDJ68610.1 - 4e-13 49.0 34.6 2e-12 46.7 32.5 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Beta-lactamase PF00144.24 CDJ68611.1 - 2.5e-39 135.5 0.0 3.1e-35 122.0 0.0 3.2 3 0 0 3 3 3 2 Beta-lactamase ABC1 PF03109.16 CDJ68611.1 - 1.7e-23 83.0 0.0 3.2e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.11 CDJ68611.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RabGAP-TBC PF00566.18 CDJ68612.1 - 2.9e-31 108.8 2.4 5.4e-30 104.7 0.1 2.8 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Kinase-like PF14531.6 CDJ68613.1 - 6.3e-18 65.1 0.0 9e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 CDJ68613.1 - 0.047 13.0 0.0 0.16 11.3 0.0 1.7 1 1 0 1 1 1 0 Protein kinase domain Mito_carr PF00153.27 CDJ68614.1 - 8.9e-31 105.7 8.9 1.5e-10 40.8 0.1 4.2 4 1 0 4 4 4 4 Mitochondrial carrier protein DNA_photolyase PF00875.18 CDJ68615.1 - 2.6e-17 63.3 0.1 6.2e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 DNA photolyase CMS1 PF14617.6 CDJ68615.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DIM1 PF02966.16 CDJ68616.1 - 2.3e-62 208.6 1.3 2.8e-62 208.4 1.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CDJ68616.1 - 0.0025 17.8 0.1 0.0034 17.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Adap_comp_sub PF00928.21 CDJ68617.1 - 2.7e-85 285.9 0.0 3.3e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ68617.1 - 3e-05 24.0 0.2 5.9e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adaptin_N PF01602.20 CDJ68618.1 - 1.1e-96 324.5 1.2 9.5e-96 321.4 1.2 1.9 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CDJ68618.1 - 3.6e-16 59.4 0.0 7.5e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CDJ68618.1 - 5.2e-06 26.6 0.8 0.14 12.2 0.0 3.6 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ68618.1 - 6.3e-06 26.5 14.7 0.0046 17.3 0.5 5.0 3 3 0 3 3 3 2 HEAT repeats HEAT PF02985.22 CDJ68618.1 - 0.017 15.3 5.4 0.25 11.7 0.3 5.0 5 0 0 5 5 5 0 HEAT repeat SRA1 PF07304.11 CDJ68618.1 - 0.09 12.6 0.2 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) P53 PF00870.18 CDJ68618.1 - 0.16 11.7 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 P53 DNA-binding domain RTP1_C1 PF10363.9 CDJ68618.1 - 0.35 11.1 2.1 15 5.9 0.1 2.9 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-C2HC_2 PF13913.6 CDJ68619.1 - 9.5e-10 38.1 13.0 3.2e-05 23.7 0.1 4.5 4 0 0 4 4 4 3 zinc-finger of a C2HC-type Tmemb_55A PF09788.9 CDJ68619.1 - 0.005 15.9 1.1 0.005 15.9 1.1 1.7 1 1 0 1 1 1 1 Transmembrane protein 55A PyrI_C PF02748.15 CDJ68619.1 - 0.0076 16.1 0.0 4.8 7.2 0.1 2.5 2 0 0 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF2318 PF10080.9 CDJ68619.1 - 0.0083 16.2 5.7 3 8.0 0.0 3.3 2 1 1 3 3 3 1 Predicted membrane protein (DUF2318) zf-ACC PF17848.1 CDJ68619.1 - 0.07 13.2 0.4 0.07 13.2 0.4 2.7 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain PriA_CRR PF18319.1 CDJ68619.1 - 0.1 12.6 2.9 9.3 6.4 0.3 3.2 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain zf_UBZ PF18439.1 CDJ68619.1 - 0.11 12.1 3.4 0.19 11.3 0.3 2.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 CDJ68619.1 - 0.21 11.6 4.7 16 5.6 0.2 4.1 4 0 0 4 4 4 0 Adenylate kinase, active site lid zinc_ribbon_12 PF11331.8 CDJ68619.1 - 2.1 8.2 5.5 17 5.3 3.1 2.5 2 0 0 2 2 2 0 Probable zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 CDJ68619.1 - 2.8 7.9 15.7 3.1 7.8 0.3 4.0 3 1 1 4 4 4 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.6 CDJ68619.1 - 4.8 7.2 7.9 98 3.0 0.1 3.4 2 1 0 2 2 2 0 Nudix N-terminal zf-TRAF_2 PF15965.5 CDJ68619.1 - 4.9 7.7 7.8 3 8.4 3.5 2.2 2 0 0 2 2 2 0 TRAF-like zinc-finger zinc-ribbons_6 PF07191.12 CDJ68619.1 - 6 6.9 9.3 1.6 8.8 4.4 2.2 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_4 PF13894.6 CDJ68619.1 - 6.3 7.9 14.1 8.5 7.5 0.1 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger HypA PF01155.19 CDJ68619.1 - 7.8 6.6 8.2 23 5.1 4.0 2.7 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 CDJ68619.1 - 9.8 6.4 10.6 7.9 6.7 3.4 3.7 3 1 1 4 4 4 0 Zinc ribbon domain SNF2_N PF00176.23 CDJ68621.1 - 4.8e-57 193.3 0.0 4.8e-57 193.3 0.0 3.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ68621.1 - 1.4e-18 67.3 0.1 7.8e-18 64.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ68621.1 - 5.6e-09 36.2 0.0 9.8e-08 32.2 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CDJ68621.1 - 4.2e-07 29.4 0.0 1.4e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Asp-B-Hydro_N PF05279.11 CDJ68621.1 - 2.9 7.9 13.8 1.1 9.3 9.7 2.3 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region eIF-3c_N PF05470.12 CDJ68623.1 - 4.1e-134 448.1 18.6 8.9e-132 440.4 18.6 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CDJ68623.1 - 5.5e-12 46.1 0.5 2.8e-11 43.9 0.1 2.5 2 0 0 2 2 2 1 PCI domain FlxA PF14282.6 CDJ68624.1 - 0.073 13.1 0.5 0.073 13.1 0.5 5.8 5 1 0 5 5 5 0 FlxA-like protein SARAF PF06682.12 CDJ68624.1 - 0.16 11.6 31.0 0.38 10.4 30.7 1.7 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3837 PF12939.7 CDJ68624.1 - 0.37 11.2 5.0 1.8 9.0 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3837) RAP1 PF07218.11 CDJ68624.1 - 4.7 5.4 10.8 6 5.0 10.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Saw1 PF11561.8 CDJ68624.1 - 8.6 5.8 15.6 0.19 11.3 7.7 2.1 2 0 0 2 2 2 0 Single strand annealing-weakened 1 Apt1 PF10351.9 CDJ68625.1 - 0.17 10.7 46.4 0.093 11.6 8.4 3.8 4 0 0 4 4 4 0 Golgi-body localisation protein domain DUF1360 PF07098.11 CDJ68625.1 - 0.32 11.0 16.2 0.96 9.4 0.2 5.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1360) SR-25 PF10500.9 CDJ68626.1 - 0.0092 15.6 19.4 0.0092 15.6 19.4 4.0 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ68626.1 - 0.084 13.4 62.2 0.35 11.4 14.8 3.3 3 0 0 3 3 3 0 TCP family transcription factor RR_TM4-6 PF06459.12 CDJ68626.1 - 0.23 11.2 62.8 0.022 14.6 32.5 3.1 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 CRT10 PF08728.10 CDJ68626.1 - 4.7 5.3 20.0 0.63 8.1 12.1 2.1 2 0 0 2 2 2 0 CRT10 Glycos_transf_2 PF00535.26 CDJ68627.1 - 3.3e-07 30.3 0.0 3.3e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 MNNL PF07657.13 CDJ68627.1 - 1.2 9.2 6.4 2.2 8.4 6.4 1.4 1 0 0 1 1 1 0 N terminus of Notch ligand SR-25 PF10500.9 CDJ68627.1 - 1.8 8.1 9.6 3.1 7.4 9.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DNA_ligase_A_M PF01068.21 CDJ68628.1 - 2.3e-34 118.8 0.1 5.2e-32 111.2 0.1 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 CDJ68628.1 - 2.1e-05 25.0 0.0 6.7e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RskA PF10099.9 CDJ68628.1 - 0.00052 20.4 7.4 0.00052 20.4 7.4 4.0 2 2 1 3 3 3 1 Anti-sigma-K factor rskA SPX PF03105.19 CDJ68628.1 - 0.04 13.8 18.8 0.31 10.9 19.0 2.1 1 1 0 1 1 1 0 SPX domain mRNA_cap_enzyme PF01331.19 CDJ68628.1 - 0.17 11.7 0.1 0.37 10.6 0.1 1.5 1 1 1 2 2 2 0 mRNA capping enzyme, catalytic domain TFIIA PF03153.13 CDJ68628.1 - 0.61 10.0 37.1 0.015 15.4 12.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Folate_carrier PF01770.18 CDJ68628.1 - 4.8 5.8 4.5 1.3 7.7 0.6 1.9 2 0 0 2 2 2 0 Reduced folate carrier DUF2722 PF10846.8 CDJ68629.1 - 0.28 10.1 17.1 0.0072 15.3 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ68629.1 - 1.5 8.8 55.1 0.73 9.8 26.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ68629.1 - 9.3 5.8 34.0 0.13 11.9 13.4 2.7 3 0 0 3 3 3 0 Spt20 family SelP_N PF04592.14 CDJ68631.1 - 0.83 9.0 25.4 0.043 13.2 18.5 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region MRC1 PF09444.10 CDJ68631.1 - 1.7 9.2 14.1 0.11 13.0 3.9 2.3 2 0 0 2 2 2 0 MRC1-like domain PIEZO PF15917.5 CDJ68631.1 - 2.7 7.4 19.2 0.2 11.1 10.0 2.1 2 0 0 2 2 2 0 Piezo FAM60A PF15396.6 CDJ68631.1 - 7.1 6.6 11.7 15 5.5 8.8 2.1 2 0 0 2 2 2 0 Protein Family FAM60A AAA PF00004.29 CDJ68633.1 - 4e-10 40.2 0.0 7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABATE PF07336.11 CDJ68633.1 - 0.02 15.6 8.8 0.084 13.5 4.4 2.3 2 0 0 2 2 2 0 Putative stress-induced transcription regulator SID-1_RNA_chan PF13965.6 CDJ68634.1 - 0.032 12.7 6.8 0.034 12.6 6.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CD20 PF04103.15 CDJ68634.1 - 0.034 14.3 0.4 0.049 13.7 0.4 1.4 1 0 0 1 1 1 0 CD20-like family AAA_23 PF13476.6 CDJ68634.1 - 0.2 12.1 18.8 0.27 11.7 18.8 1.2 1 0 0 1 1 1 0 AAA domain Ureide_permease PF07168.11 CDJ68634.1 - 0.53 9.0 10.4 0.71 8.6 10.4 1.2 1 0 0 1 1 1 0 Ureide permease TraT PF05818.12 CDJ68634.1 - 1.1 8.8 24.8 1.5 8.4 24.8 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein XRN_M PF17846.1 CDJ68634.1 - 1.8 7.4 16.7 2.3 7.1 16.7 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Serinc PF03348.15 CDJ68634.1 - 1.8 7.4 17.5 2.1 7.2 17.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM199X PF15814.5 CDJ68634.1 - 2.5 7.1 23.1 3.2 6.7 23.1 1.2 1 0 0 1 1 1 0 Protein family FAM199X CSG2 PF16965.5 CDJ68634.1 - 3.5 6.5 11.4 3.5 6.5 11.4 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator eIF-3_zeta PF05091.12 CDJ68634.1 - 4.2 6.2 30.1 5.3 5.9 30.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) O-antigen_lig PF13425.6 CDJ68634.1 - 6.1 5.5 8.7 6.6 5.4 8.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein BAF1_ABF1 PF04684.13 CDJ68634.1 - 6.3 5.7 33.0 8.1 5.4 33.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Peptidase_U57 PF05582.12 CDJ68634.1 - 7 5.8 14.7 10 5.3 14.7 1.3 1 0 0 1 1 1 0 YabG peptidase U57 NEMP PF10225.9 CDJ68634.1 - 8 6.0 8.3 9.8 5.8 8.3 1.2 1 0 0 1 1 1 0 NEMP family NUDE_C PF04880.13 CDJ68634.1 - 8.1 6.9 20.7 11 6.4 20.7 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Spem1 PF15670.5 CDJ68634.1 - 9.5 5.7 21.4 11 5.5 21.4 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 PPP4R2 PF09184.11 CDJ68634.1 - 9.9 5.7 15.9 11 5.4 15.9 1.0 1 0 0 1 1 1 0 PPP4R2 RskA PF10099.9 CDJ68635.1 - 0.0076 16.6 12.4 0.0076 16.6 12.4 11.8 7 4 1 8 8 8 2 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ68635.1 - 0.012 15.7 0.9 0.012 15.7 0.9 6.8 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 CDJ68635.1 - 0.042 14.2 21.9 0.18 12.2 12.0 3.9 3 0 0 3 3 3 0 Enhancer of polycomb-like SID-1_RNA_chan PF13965.6 CDJ68635.1 - 0.11 10.8 1.0 0.25 9.7 1.0 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MAJIN PF15077.6 CDJ68635.1 - 0.2 11.4 4.0 0.84 9.4 4.0 2.1 1 0 0 1 1 1 0 Membrane-anchored junction protein XAP5 PF04921.14 CDJ68635.1 - 0.28 11.0 9.0 0.093 12.5 5.2 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator DUF5523 PF17661.1 CDJ68635.1 - 0.37 10.5 23.6 0.27 10.9 19.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Crust_neuro_H PF03858.13 CDJ68635.1 - 3.3 8.6 7.5 28 5.6 0.2 3.8 4 0 0 4 4 4 0 Crustacean neurohormone H VIR_N PF15912.5 CDJ68635.1 - 6.8 6.2 10.8 14 5.2 10.8 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal Neur_chan_memb PF02932.16 CDJ68635.1 - 7.7 6.5 15.6 0.16 12.0 2.9 3.7 4 0 0 4 4 4 0 Neurotransmitter-gated ion-channel transmembrane region EMG1 PF03587.14 CDJ68637.1 - 3.2e-15 56.3 0.0 2.5e-12 46.9 0.0 3.6 1 1 0 1 1 1 1 EMG1/NEP1 methyltransferase MDM1 PF15501.6 CDJ68637.1 - 0.0051 16.0 49.9 0.0051 16.0 49.9 4.0 3 1 0 3 3 3 1 Nuclear protein MDM1 DUF1117 PF06547.12 CDJ68638.1 - 9.3 6.8 9.3 28 5.3 6.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) PSP PF04046.16 CDJ68640.1 - 2e-19 69.2 6.7 4e-19 68.2 6.7 1.5 1 0 0 1 1 1 1 PSP zf-HIT PF04438.16 CDJ68642.1 - 3e-08 33.4 13.1 5.4e-08 32.6 13.1 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 CDJ68642.1 - 0.64 10.2 14.5 1.8 8.8 14.5 1.8 1 0 0 1 1 1 0 MYND finger DNA_pol_viral_N PF00242.17 CDJ68642.1 - 0.69 9.3 7.8 1.2 8.6 7.8 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PAT1 PF09770.9 CDJ68642.1 - 5 5.3 38.0 0.85 7.8 12.4 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF2052 PF09747.9 CDJ68642.1 - 5.2 7.1 32.5 1.6 8.8 7.5 2.4 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4175 PF13779.6 CDJ68642.1 - 6.7 4.5 64.3 0.09 10.7 26.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) ubiquitin PF00240.23 CDJ68643.1 - 1.8e-09 37.2 0.0 1.8e-07 30.8 0.0 3.2 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CDJ68643.1 - 8.2e-08 32.3 0.1 8.2e-08 32.3 0.1 4.6 4 2 1 5 5 5 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 CDJ68643.1 - 0.00045 20.0 0.0 0.0035 17.2 0.0 2.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 CDJ68643.1 - 0.0012 19.5 0.1 0.0012 19.5 0.1 2.7 3 0 0 3 3 3 1 WXG100 protein secretion system (Wss), protein YukD DUF2407 PF10302.9 CDJ68643.1 - 0.011 16.3 0.7 0.011 16.3 0.7 5.9 4 1 0 4 4 4 0 DUF2407 ubiquitin-like domain MRAP PF15183.6 CDJ68644.1 - 0.078 12.9 2.4 3.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family ODV-E18 PF10717.9 CDJ68644.1 - 0.15 12.0 0.3 0.15 12.0 0.3 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 IMUP PF15761.5 CDJ68644.1 - 1.2 9.9 7.4 1.5 9.5 7.4 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein Adaptin_N PF01602.20 CDJ68645.1 - 1.2e-28 100.0 0.1 5e-25 88.1 0.4 2.4 2 1 0 2 2 2 2 Adaptin N terminal region AP4E_app_platf PF14807.6 CDJ68645.1 - 0.00016 21.9 0.0 0.00076 19.8 0.0 2.2 2 0 0 2 2 2 1 Adaptin AP4 complex epsilon appendage platform Spt20 PF12090.8 CDJ68645.1 - 0.0012 18.5 4.4 0.0012 18.5 4.4 5.0 5 0 0 5 5 5 3 Spt20 family LSM PF01423.22 CDJ68647.1 - 4.1e-17 61.6 0.8 4.9e-17 61.4 0.8 1.1 1 0 0 1 1 1 1 LSM domain Rad51 PF08423.11 CDJ68649.1 - 1.5e-08 34.3 0.0 2.8e-05 23.5 0.1 3.0 3 0 0 3 3 3 2 Rad51 AAA_25 PF13481.6 CDJ68649.1 - 0.00042 19.9 0.1 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain RecA PF00154.21 CDJ68649.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein ATPase PF06745.13 CDJ68649.1 - 0.034 13.5 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 KaiC XPG_I PF00867.18 CDJ68650.1 - 1.4e-12 47.7 0.1 3.4e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDJ68650.1 - 1e-10 41.9 0.0 8.5e-05 23.0 0.0 2.7 3 0 0 3 3 3 2 XPG N-terminal domain DUF4179 PF13786.6 CDJ68650.1 - 8.2 7.0 13.5 22 5.6 0.4 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) AP2 PF00847.20 CDJ68651.1 - 9.8e-13 48.1 0.7 9.8e-13 48.1 0.7 3.5 3 1 1 4 4 4 1 AP2 domain SR-25 PF10500.9 CDJ68651.1 - 0.042 13.5 34.1 0.021 14.4 7.5 3.9 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein DctA-YdbH PF11739.8 CDJ68652.1 - 0.00099 18.9 4.3 0.0027 17.5 4.3 1.7 1 0 0 1 1 1 1 Dicarboxylate transport DUF4763 PF15960.5 CDJ68652.1 - 0.0079 15.5 0.5 0.0079 15.5 0.5 6.0 5 2 1 6 6 6 1 Domain of unknown function (DUF4763) FlxA PF14282.6 CDJ68652.1 - 0.022 14.7 0.2 0.022 14.7 0.2 5.6 5 1 0 5 5 5 0 FlxA-like protein Collagen PF01391.18 CDJ68653.1 - 2.4e-05 24.0 10.8 4.4e-05 23.2 10.8 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF5523 PF17661.1 CDJ68653.1 - 0.0066 16.2 0.2 0.014 15.1 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5523) Spt20 PF12090.8 CDJ68653.1 - 0.01 15.5 20.9 0.053 13.1 12.7 2.4 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ68653.1 - 0.33 9.9 20.3 0.27 10.1 11.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ68653.1 - 2.7 9.0 8.7 1.1 10.2 4.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) LYTB PF02401.18 CDJ68654.1 - 3.7e-67 226.4 1.5 9.3e-54 182.4 0.1 2.2 2 0 0 2 2 2 2 LytB protein DUF5320 PF17253.2 CDJ68654.1 - 0.51 11.4 5.9 0.37 11.9 2.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) FHA PF00498.26 CDJ68656.1 - 1.9e-17 63.4 0.1 3.3e-09 37.0 0.1 2.5 2 0 0 2 2 2 2 FHA domain Collagen PF01391.18 CDJ68656.1 - 1.7e-05 24.5 15.5 1.7e-05 24.5 15.5 6.7 3 2 1 4 4 4 2 Collagen triple helix repeat (20 copies) SR-25 PF10500.9 CDJ68657.1 - 0.015 14.9 4.5 0.03 13.9 4.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ParB PF08775.10 CDJ68657.1 - 0.19 12.2 3.0 2.8 8.4 0.3 2.4 1 1 1 2 2 2 0 ParB family IMUP PF15761.5 CDJ68657.1 - 0.26 12.0 4.7 0.81 10.4 4.7 1.9 1 0 0 1 1 1 0 Immortalisation up-regulated protein DASH_Dad2 PF08654.10 CDJ68657.1 - 2 8.9 8.3 9.5 6.7 0.1 4.0 4 1 1 5 5 5 0 DASH complex subunit Dad2 RRM_1 PF00076.22 CDJ68658.1 - 9.1e-23 79.9 0.0 4.4e-12 45.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ68658.1 - 4.6e-09 36.3 0.0 0.0034 17.4 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif SUIM_assoc PF16619.5 CDJ68658.1 - 0.0085 16.1 24.8 0.43 10.7 2.6 3.7 3 0 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ68658.1 - 1.7 8.2 27.7 1.7 8.2 0.9 3.2 3 0 0 3 3 3 0 Spt20 family D123 PF07065.14 CDJ68659.1 - 7e-16 58.3 0.7 9.8e-10 38.1 0.0 4.6 5 1 0 5 5 5 2 D123 SPX PF03105.19 CDJ68659.1 - 6.5e-05 23.0 0.0 6.5e-05 23.0 0.0 3.2 2 1 1 3 3 3 2 SPX domain SUIM_assoc PF16619.5 CDJ68659.1 - 6.3 6.9 77.3 1.3 9.2 1.1 6.6 5 1 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Miga PF10265.9 CDJ68659.1 - 10 5.0 9.3 40 3.0 9.3 2.0 1 0 0 1 1 1 0 Mitoguardin EamA PF00892.20 CDJ68660.1 - 5.7e-07 29.8 39.5 1.8e-05 24.9 13.7 3.6 3 0 0 3 3 3 3 EamA-like transporter family tRNA_anti-like PF12869.7 CDJ68660.1 - 9.1 5.9 9.7 12 5.5 2.4 3.2 3 0 0 3 3 3 0 tRNA_anti-like His_Phos_2 PF00328.22 CDJ68662.1 - 7.8e-45 153.8 12.2 2.2e-26 93.1 0.1 5.5 5 0 0 5 5 5 5 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CDJ68662.1 - 2.7e-33 114.0 0.0 4.9e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain HEAT PF02985.22 CDJ68663.1 - 1.5e-12 46.6 10.4 0.0038 17.4 0.0 5.8 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 CDJ68663.1 - 2.7e-07 30.9 4.3 2.1e-06 28.0 0.5 6.5 6 0 0 6 6 6 2 HEAT repeats Pkinase PF00069.25 CDJ68663.1 - 7e-06 25.6 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 CDJ68663.1 - 4.3e-05 23.6 0.0 0.078 13.0 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 SUIM_assoc PF16619.5 CDJ68663.1 - 0.01 15.9 53.4 0.12 12.5 0.7 7.2 6 0 0 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 HEAT_EZ PF13513.6 CDJ68663.1 - 0.074 13.6 0.0 0.074 13.6 0.0 9.6 10 0 0 10 10 10 0 HEAT-like repeat WD40 PF00400.32 CDJ68663.1 - 0.081 13.8 0.6 0.52 11.3 0.1 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat SPX PF03105.19 CDJ68663.1 - 2.6 7.9 34.6 0.55 10.1 0.3 4.3 4 0 0 4 4 4 0 SPX domain AP2 PF00847.20 CDJ68664.1 - 0.0021 18.3 8.7 0.088 13.0 0.6 2.5 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.6 CDJ68665.1 - 6.1e-09 36.1 0.1 0.00017 21.8 0.0 3.1 3 0 0 3 3 3 2 AP2-coincident C-terminal DUF4094 PF13334.6 CDJ68666.1 - 0.099 13.1 2.4 0.12 12.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) TFIIA PF03153.13 CDJ68666.1 - 0.67 9.9 30.9 1.8 8.5 18.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CdvA PF18822.1 CDJ68666.1 - 0.77 9.6 5.9 0.13 12.1 2.3 1.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain BLOC1_2 PF10046.9 CDJ68666.1 - 1.3 9.4 6.9 0.73 10.2 3.4 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 CDJ68666.1 - 3 7.3 10.0 3 7.4 5.2 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit CLPTM1 PF05602.12 CDJ68667.1 - 1.6e-27 96.6 0.0 8.6e-26 90.9 0.0 2.4 2 1 0 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) AMO PF02461.16 CDJ68667.1 - 0.0078 16.0 0.8 0.0078 16.0 0.8 2.0 2 0 0 2 2 2 1 Ammonia monooxygenase DUF3402 PF11882.8 CDJ68668.1 - 0.067 12.3 0.6 0.17 10.9 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3402) RseA_C PF03873.13 CDJ68668.1 - 3 8.2 13.0 2.1 8.7 0.5 3.4 3 1 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain PqqD PF05402.12 CDJ68669.1 - 1.1 9.6 6.1 9.6 6.6 0.8 4.4 4 1 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) DUF3439 PF11921.8 CDJ68673.1 - 0.11 12.5 1.0 0.23 11.4 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.25 CDJ68674.1 - 9.7e-18 64.5 0.0 9.7e-18 64.5 0.0 3.7 3 2 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ68674.1 - 1.5e-09 37.5 0.0 5.1e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase LMWPc PF01451.21 CDJ68676.1 - 1.7e-24 86.8 0.0 2.3e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase tRNA-synt_2d PF01409.20 CDJ68677.1 - 3.5e-29 102.0 0.1 4.9e-22 78.6 0.0 2.6 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) YppG PF14179.6 CDJ68677.1 - 0.0077 16.9 13.1 0.0077 16.9 13.1 1.7 2 0 0 2 2 2 1 YppG-like protein PheRS_DBD1 PF18552.1 CDJ68677.1 - 0.031 14.0 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 PheRS DNA binding domain 1 TFIIA PF03153.13 CDJ68677.1 - 0.042 13.9 23.5 0.06 13.3 23.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ68677.1 - 0.41 11.3 8.4 0.88 10.2 8.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein PAT1 PF09770.9 CDJ68677.1 - 1.2 7.3 11.9 1.6 6.9 11.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 CDJ68677.1 - 3.8 8.2 15.6 6.4 7.4 15.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s PF00428.19 CDJ68678.1 - 6.9 7.3 9.7 1.5 9.5 6.3 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_60s PF00428.19 CDJ68679.1 - 0.00022 21.7 9.0 0.00022 21.7 9.0 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF3123 PF11321.8 CDJ68679.1 - 0.048 14.3 2.4 3.6 8.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) OAD_gamma PF04277.13 CDJ68679.1 - 0.049 14.2 2.4 0.049 14.2 2.4 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CCDC24 PF15669.5 CDJ68679.1 - 0.19 11.5 3.6 0.33 10.8 1.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Period_C PF12114.8 CDJ68679.1 - 0.25 10.9 5.9 0.42 10.2 5.9 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SR-25 PF10500.9 CDJ68679.1 - 0.29 10.7 11.8 0.56 9.8 11.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ68679.1 - 0.39 11.0 15.2 0.49 10.7 10.7 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain WBP-1 PF11669.8 CDJ68680.1 - 0.26 11.9 2.8 0.38 11.4 0.1 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 DMSP_lyase PF16867.5 CDJ68680.1 - 0.27 10.9 6.6 0.03 14.0 1.6 2.0 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase CBP_BcsG PF11658.8 CDJ68680.1 - 2.1 6.6 6.4 0.32 9.3 2.2 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG Metallophos PF00149.28 CDJ68682.1 - 0.041 14.4 0.3 0.22 12.0 0.0 1.9 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase ABC_tran PF00005.27 CDJ68684.1 - 1.6e-28 99.9 0.0 3.8e-27 95.5 0.0 3.0 2 1 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 CDJ68684.1 - 4.1e-21 75.9 0.2 1e-20 74.6 0.2 1.7 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 CDJ68684.1 - 3.3e-05 23.8 0.0 0.32 10.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CDJ68684.1 - 0.00042 20.7 0.1 0.00042 20.7 0.1 3.5 4 0 0 4 4 3 1 AAA ATPase domain Rad17 PF03215.15 CDJ68684.1 - 0.0014 18.6 0.1 0.0036 17.3 0.0 1.6 2 0 0 2 2 1 1 Rad17 P-loop domain Zeta_toxin PF06414.12 CDJ68684.1 - 0.0062 15.8 0.0 0.017 14.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 CDJ68684.1 - 0.0074 16.2 0.1 0.0074 16.2 0.1 1.8 2 0 0 2 2 1 1 RsgA GTPase AAA PF00004.29 CDJ68684.1 - 0.0089 16.5 0.7 2.4 8.6 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CDJ68684.1 - 0.011 15.5 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CDJ68684.1 - 0.011 16.0 0.7 0.046 14.0 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 CDJ68684.1 - 0.042 14.4 0.4 0.16 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Neur_chan_memb PF02932.16 CDJ68684.1 - 0.044 13.9 7.0 3.1 7.8 3.5 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MobB PF03205.14 CDJ68684.1 - 0.052 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MecA PF05389.12 CDJ68684.1 - 0.06 13.0 3.1 0.24 11.0 1.4 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) T2SSE PF00437.20 CDJ68684.1 - 0.071 12.2 0.4 0.21 10.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 CDJ68684.1 - 0.072 13.3 0.0 0.072 13.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain GramPos_pilinD1 PF16555.5 CDJ68684.1 - 0.073 13.2 3.3 4.6 7.4 1.2 2.4 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain MeaB PF03308.16 CDJ68684.1 - 0.075 12.0 0.1 0.075 12.0 0.1 1.9 2 0 0 2 2 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 CDJ68684.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4199 PF13858.6 CDJ68684.1 - 0.15 12.4 8.0 1.4 9.3 0.1 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF4199) CSG2 PF16965.5 CDJ68684.1 - 0.16 10.9 1.4 0.3 10.0 0.5 1.8 2 0 0 2 2 2 0 Ceramide synthase regulator NTPase_1 PF03266.15 CDJ68684.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF87 PF01935.17 CDJ68684.1 - 0.33 11.0 0.1 0.33 11.0 0.1 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain UBA_e1_thiolCys PF10585.9 CDJ68684.1 - 0.36 10.7 5.8 13 5.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site AAA_23 PF13476.6 CDJ68684.1 - 0.54 10.7 16.6 0.56 10.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain EIIBC-GUT_N PF03612.14 CDJ68684.1 - 0.87 9.3 5.4 1.7 8.4 2.6 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Thymidylate_kin PF02223.17 CDJ68684.1 - 1.1 8.9 5.1 8.9 5.9 0.0 3.2 3 0 0 3 3 3 0 Thymidylate kinase CobA_CobO_BtuR PF02572.15 CDJ68684.1 - 1.7 8.9 7.3 5.5 7.2 0.1 2.7 3 0 0 3 3 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Lin-8 PF03353.15 CDJ68684.1 - 2.1 7.8 18.5 1.6 8.2 5.6 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ68684.1 - 2.5 7.9 14.6 0.47 10.3 5.6 2.1 2 0 0 2 2 2 0 SPX domain DUF2722 PF10846.8 CDJ68684.1 - 3.9 6.3 29.2 2.6 6.9 8.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ68684.1 - 4.2 7.7 10.0 2.7 8.4 1.7 2.5 3 0 0 3 3 2 0 Enhancer of polycomb-like Presenilin PF01080.17 CDJ68684.1 - 6.2 5.5 14.9 3.4 6.3 1.6 2.3 2 0 0 2 2 2 0 Presenilin tRNA_synt_1c_R2 PF04557.15 CDJ68684.1 - 9.2 7.3 9.8 40 5.2 5.3 2.6 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 TFIIA PF03153.13 CDJ68685.1 - 0.12 12.3 8.4 0.15 12.0 8.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MLIP PF15274.6 CDJ68685.1 - 1.7 8.5 8.6 3 7.7 8.6 1.5 1 0 0 1 1 1 0 Muscular LMNA-interacting protein SR-25 PF10500.9 CDJ68686.1 - 0.00042 20.0 30.1 0.0055 16.3 1.9 4.6 4 0 0 4 4 4 3 Nuclear RNA-splicing-associated protein P_proprotein PF01483.20 CDJ68686.1 - 0.034 14.2 5.8 0.13 12.3 2.2 3.3 2 1 1 3 3 3 0 Proprotein convertase P-domain RskA PF10099.9 CDJ68687.1 - 0.0064 16.8 11.5 0.0092 16.3 11.5 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Trp_oprn_chp PF09534.10 CDJ68687.1 - 0.26 11.1 2.5 0.36 10.6 2.5 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SID-1_RNA_chan PF13965.6 CDJ68687.1 - 0.45 8.9 4.3 0.54 8.6 4.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 X PF00739.19 CDJ68687.1 - 0.48 10.5 4.6 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Trans-activation protein X DUF4175 PF13779.6 CDJ68687.1 - 1.5 6.6 31.9 1.7 6.5 31.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SR-25 PF10500.9 CDJ68687.1 - 2.3 7.8 30.2 0.013 15.1 17.4 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.7 CDJ68687.1 - 7.7 4.5 21.3 8.8 4.3 21.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DcuA_DcuB PF03605.14 CDJ68687.1 - 8.9 5.1 9.7 3.9 6.3 0.2 2.0 1 1 1 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter SOBP PF15279.6 CDJ68687.1 - 10 6.7 23.5 12 6.4 23.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TFIIB PF00382.19 CDJ68688.1 - 1e-10 41.5 0.1 3.8e-10 39.7 0.1 2.1 1 0 0 1 1 1 1 Transcription factor TFIIB repeat BRF1 PF07741.13 CDJ68688.1 - 0.26 11.6 2.4 2.8 8.4 0.2 2.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain SUIM_assoc PF16619.5 CDJ68688.1 - 0.34 11.0 6.0 0.82 9.8 6.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CytochromB561_N PF09786.9 CDJ68689.1 - 0.27 10.2 0.3 0.3 10.0 0.3 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF2627 PF11118.8 CDJ68689.1 - 1.9 9.1 5.4 0.35 11.5 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) DUF3824 PF12868.7 CDJ68691.1 - 0.054 14.2 3.0 0.054 14.2 3.0 5.3 4 2 0 4 4 4 0 Domain of unknwon function (DUF3824) SARAF PF06682.12 CDJ68691.1 - 3.2 7.3 32.2 0.39 10.3 18.2 2.4 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CRT10 PF08728.10 CDJ68691.1 - 3.7 5.6 9.7 4.6 5.3 9.7 1.1 1 0 0 1 1 1 0 CRT10 NAD_binding_2 PF03446.15 CDJ68692.1 - 1.5e-13 51.2 0.2 1.9e-13 50.9 0.2 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CDJ68692.1 - 0.00045 20.1 0.1 0.00047 20.1 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RAP PF08373.10 CDJ68693.1 - 6.1e-05 23.0 0.0 0.019 15.1 0.0 2.5 2 0 0 2 2 2 2 RAP domain CNDH2_C PF16858.5 CDJ68693.1 - 0.088 12.7 35.0 0.42 10.4 16.1 3.3 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term GNAT_acetyltr_2 PF13718.6 CDJ68693.1 - 9.6 5.5 25.0 0.39 10.1 12.1 3.5 3 0 0 3 3 3 0 GNAT acetyltransferase 2 AMMECR1 PF01871.17 CDJ68695.1 - 4.3e-31 107.8 0.7 1.4e-30 106.1 0.0 2.2 2 0 0 2 2 2 1 AMMECR1 DASH_Spc34 PF08657.10 CDJ68695.1 - 0.0061 16.4 7.7 0.0061 16.4 7.7 4.5 3 1 1 4 4 4 1 DASH complex subunit Spc34 CTD_bind PF04818.13 CDJ68696.1 - 0.011 16.6 0.0 0.12 13.3 0.0 2.8 2 1 0 2 2 2 0 RNA polymerase II-binding domain. Ribosomal_60s PF00428.19 CDJ68696.1 - 0.26 11.9 64.6 0.14 12.7 12.4 5.0 5 0 0 5 5 5 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ68697.1 - 0.00038 20.8 1.3 0.00038 20.8 1.3 9.4 4 3 3 7 7 7 2 Anti-sigma-K factor rskA Scs3p PF10261.9 CDJ68697.1 - 0.00041 19.9 0.6 0.00041 19.9 0.6 3.7 4 1 1 5 5 5 1 Inositol phospholipid synthesis and fat-storage-inducing TM Peroxin-3 PF04882.12 CDJ68697.1 - 2.3 7.1 0.0 2.3 7.1 0.0 5.8 3 2 0 3 3 3 0 Peroxin-3 DUF2207 PF09972.9 CDJ68697.1 - 3.2 6.4 4.0 15 4.2 0.0 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) RskA PF10099.9 CDJ68699.1 - 0.0051 17.1 11.4 0.0051 17.1 11.4 2.9 2 1 1 3 3 3 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ68699.1 - 0.0094 15.6 10.7 0.0094 15.6 10.7 2.3 2 0 0 2 2 2 1 Spt20 family DUF2722 PF10846.8 CDJ68699.1 - 0.014 14.4 29.4 0.17 10.8 9.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) bMG10 PF17973.1 CDJ68699.1 - 0.035 14.3 0.1 0.035 14.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain DUF4746 PF15928.5 CDJ68699.1 - 0.063 12.7 7.3 0.55 9.6 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Ferlin_C PF16165.5 CDJ68699.1 - 0.1 12.6 3.6 1.3 8.9 0.7 2.1 2 0 0 2 2 2 0 Ferlin C-terminus CCDC53 PF10152.9 CDJ68699.1 - 0.11 13.0 13.6 0.79 10.1 4.3 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex MecA PF05389.12 CDJ68699.1 - 0.11 12.1 8.8 1.7 8.2 0.3 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Otopetrin PF03189.13 CDJ68699.1 - 0.12 11.1 2.4 0.16 10.8 2.4 1.2 1 0 0 1 1 1 0 Otopetrin DUF4834 PF16118.5 CDJ68699.1 - 0.19 12.7 12.9 0.89 10.6 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SpoIIP PF07454.11 CDJ68699.1 - 0.37 10.2 12.4 2 7.8 1.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF778 PF05608.12 CDJ68699.1 - 0.47 10.8 8.1 0.15 12.4 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF778) BORG_CEP PF14957.6 CDJ68699.1 - 0.61 11.2 6.2 13 7.0 0.1 2.2 2 0 0 2 2 2 0 Cdc42 effector CLN3 PF02487.17 CDJ68699.1 - 0.77 8.7 8.7 1.9 7.4 0.2 2.1 2 0 0 2 2 2 0 CLN3 protein TERB2 PF15101.6 CDJ68699.1 - 1.1 9.2 23.9 0.62 10.1 2.9 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Mak16 PF04874.14 CDJ68699.1 - 1.3 9.7 11.8 8 7.1 0.8 2.3 2 0 0 2 2 2 0 Mak16 protein C-terminal region CPSF100_C PF13299.6 CDJ68699.1 - 1.4 9.1 8.9 9.3 6.4 3.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S49_N PF08496.10 CDJ68699.1 - 1.4 8.9 14.0 3.7 7.6 5.7 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Suf PF05843.14 CDJ68699.1 - 1.7 8.6 18.8 0.31 11.0 2.6 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) WRNPLPNID PF15017.6 CDJ68699.1 - 1.7 9.6 20.0 0.14 13.1 3.1 2.3 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DUF4175 PF13779.6 CDJ68699.1 - 1.8 6.4 34.0 0.21 9.5 14.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) MMR1 PF08505.10 CDJ68699.1 - 2.3 8.4 18.6 1.3 9.2 2.0 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein EOS1 PF12326.8 CDJ68699.1 - 2.4 8.1 4.3 38 4.2 2.3 2.1 2 0 0 2 2 2 0 N-glycosylation protein Ribosomal_60s PF00428.19 CDJ68699.1 - 2.8 8.6 14.2 0.29 11.8 5.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Rxt3 PF08642.10 CDJ68699.1 - 3.6 8.4 7.3 6.4 7.6 1.6 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Pinin_SDK_memA PF04696.13 CDJ68699.1 - 4.1 7.5 33.2 4 7.5 14.8 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF1980 PF09323.10 CDJ68699.1 - 4.5 7.2 7.3 19 5.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Folate_carrier PF01770.18 CDJ68699.1 - 4.6 5.9 6.9 6.6 5.3 0.1 2.1 2 0 0 2 2 2 0 Reduced folate carrier RR_TM4-6 PF06459.12 CDJ68699.1 - 5 6.9 13.7 7.4 6.3 1.7 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 BRF1 PF07741.13 CDJ68699.1 - 5.3 7.5 14.4 6.3 7.2 5.0 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Folliculin PF11704.8 CDJ68699.1 - 6 6.7 11.5 5.3 6.9 0.5 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport FAM150 PF15129.6 CDJ68699.1 - 6.5 6.9 14.2 9.3 6.4 0.8 2.3 2 0 0 2 2 2 0 FAM150 family WASH-7_C PF14746.6 CDJ68699.1 - 6.5 6.4 18.3 2.7 7.7 1.8 2.2 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Med7 PF05983.11 CDJ68700.1 - 4.4e-22 79.1 0.6 4.4e-22 79.1 0.6 2.1 2 0 0 2 2 2 1 MED7 protein TFIIA PF03153.13 CDJ68700.1 - 0.00045 20.4 48.0 0.0038 17.3 32.0 2.0 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 CDJ68700.1 - 0.0044 17.4 17.8 0.0099 16.3 11.1 2.1 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex SARAF PF06682.12 CDJ68700.1 - 0.0046 16.7 15.5 0.15 11.7 1.5 2.2 2 0 0 2 2 2 2 SOCE-associated regulatory factor of calcium homoeostasis DUF572 PF04502.13 CDJ68700.1 - 0.16 11.6 11.0 0.036 13.7 6.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) Suf PF05843.14 CDJ68700.1 - 0.28 11.1 26.3 0.6 10.0 2.0 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) ALMT PF11744.8 CDJ68700.1 - 0.3 9.9 13.4 0.0099 14.7 7.1 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter Band_3_cyto PF07565.13 CDJ68700.1 - 0.34 10.7 15.1 0.21 11.3 9.4 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Rav1p_C PF12234.8 CDJ68700.1 - 0.35 9.2 11.0 0.61 8.4 11.0 1.3 1 0 0 1 1 1 0 RAVE protein 1 C terminal RR_TM4-6 PF06459.12 CDJ68700.1 - 0.52 10.1 15.1 0.028 14.3 6.4 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SKA1 PF07160.12 CDJ68700.1 - 0.63 9.8 23.8 0.045 13.6 15.6 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Connexin PF00029.19 CDJ68700.1 - 1.2 8.9 8.0 3.5 7.3 4.6 2.2 2 0 0 2 2 2 0 Connexin eIF-3_zeta PF05091.12 CDJ68700.1 - 1.3 7.9 20.4 0.71 8.8 10.7 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex14_N PF04695.13 CDJ68700.1 - 2 9.1 38.8 0.33 11.6 6.8 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LIM_bind PF01803.16 CDJ68700.1 - 2.8 7.4 15.4 6 6.3 9.6 2.2 2 0 0 2 2 2 0 LIM-domain binding protein Nop25 PF09805.9 CDJ68700.1 - 2.8 8.4 21.6 0.58 10.6 15.2 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Macoilin PF09726.9 CDJ68700.1 - 3.3 6.2 14.5 4.4 5.7 14.5 1.1 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 CDJ68700.1 - 4.3 5.1 18.3 0.21 9.5 10.7 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 CDJ68700.1 - 4.8 5.6 18.6 8.7 4.7 18.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family SpoIIP PF07454.11 CDJ68700.1 - 5.9 6.3 17.0 3 7.2 10.5 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TMEM174 PF15029.6 CDJ68700.1 - 6.4 6.4 7.9 12 5.6 0.4 2.2 2 0 0 2 2 2 0 Transmembrane protein 174 NPR1_interact PF15699.5 CDJ68700.1 - 6.5 7.4 19.2 1.7 9.3 11.0 2.2 2 0 0 2 2 2 0 NPR1 interacting Neur_chan_memb PF02932.16 CDJ68700.1 - 8.2 6.4 16.2 6.2 6.8 10.6 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Cyclin PF08613.11 CDJ68702.1 - 1.8e-13 51.2 5.6 1.8e-13 51.2 5.6 3.6 3 1 0 3 3 3 1 Cyclin Pex14_N PF04695.13 CDJ68702.1 - 0.00091 19.9 30.3 0.00091 19.9 30.3 5.3 6 2 0 6 6 6 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Ureide_permease PF07168.11 CDJ68702.1 - 0.58 8.8 2.2 1.5 7.5 2.2 1.7 1 0 0 1 1 1 0 Ureide permease SID-1_RNA_chan PF13965.6 CDJ68702.1 - 0.97 7.8 1.9 2.2 6.6 1.9 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Adaptin_binding PF10199.9 CDJ68702.1 - 4 8.1 31.6 5 7.7 13.7 4.1 3 2 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 Arm PF00514.23 CDJ68705.1 - 2.8e-09 36.7 40.9 0.00016 21.6 0.8 8.8 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CDJ68705.1 - 0.012 16.1 0.4 0.012 16.1 0.4 6.8 6 3 0 6 6 6 0 HEAT-like repeat Reoviridae_Vp9 PF08978.10 CDJ68705.1 - 0.22 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Reoviridae VP9 NOC3p PF07540.11 CDJ68706.1 - 7.4e-11 42.4 0.8 7.4e-11 42.4 0.8 2.9 3 1 0 3 3 3 1 Nucleolar complex-associated protein zf-met2 PF12907.7 CDJ68707.1 - 2.1e-19 69.3 2.0 3.4e-19 68.7 2.0 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 CDJ68707.1 - 0.00011 22.9 4.5 0.00011 22.9 4.5 1.8 2 0 0 2 2 2 1 4F5 protein family zf-BED PF02892.15 CDJ68707.1 - 0.072 13.1 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.6 CDJ68707.1 - 0.15 11.8 0.8 0.31 10.8 0.8 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Chromo PF00385.24 CDJ68708.1 - 1.1e-09 38.1 0.1 2.8e-09 36.7 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DSPc PF00782.20 CDJ68709.1 - 1.1e-06 28.5 0.0 2.3e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ68709.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DEAD_assoc PF08494.11 CDJ68709.1 - 0.098 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 DEAD/H associated Maf PF02545.14 CDJ68710.1 - 5.9e-21 75.0 0.3 1.2e-09 38.2 0.0 2.9 2 1 0 2 2 2 2 Maf-like protein Efg1 PF10153.9 CDJ68711.1 - 1.4e-16 60.8 8.9 1.4e-16 60.8 8.9 2.2 2 0 0 2 2 2 1 rRNA-processing protein Efg1 Coatomer_WDAD PF04053.14 CDJ68712.1 - 1.9e-73 248.1 0.0 1.1e-72 245.6 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 CDJ68712.1 - 1.4e-72 244.8 0.0 1.9e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CDJ68712.1 - 6.4e-23 80.6 10.4 2.1e-07 31.5 0.5 5.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ68712.1 - 9.9e-12 45.0 0.3 4.5e-07 30.1 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ68712.1 - 0.0088 14.7 2.4 1.7 7.2 0.3 2.5 2 1 0 2 2 2 2 Nucleoporin Nup120/160 TPR_2 PF07719.17 CDJ68712.1 - 0.019 15.0 4.0 3.1 8.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 CDJ68712.1 - 0.021 15.0 0.3 0.064 13.5 0.3 1.8 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 TCL1_MTCP1 PF01840.17 CDJ68712.1 - 0.023 14.3 0.2 0.051 13.2 0.2 1.5 1 0 0 1 1 1 0 TCL1/MTCP1 family TPR_16 PF13432.6 CDJ68712.1 - 0.05 14.2 7.3 25 5.6 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Nucleoporin_N PF08801.11 CDJ68712.1 - 0.26 10.0 0.1 0.83 8.3 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like AAA_2 PF07724.14 CDJ68713.1 - 1.7e-51 174.7 0.0 4.8e-50 170.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CDJ68713.1 - 2.2e-33 114.3 0.7 2.2e-33 114.3 0.7 2.5 3 0 0 3 3 2 1 AAA lid domain AAA PF00004.29 CDJ68713.1 - 7.6e-24 84.6 0.0 1.7e-10 41.4 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDJ68713.1 - 4.8e-20 71.4 1.0 2.2e-19 69.3 0.3 2.7 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 CDJ68713.1 - 1.7e-17 63.2 0.2 6.4e-09 35.8 0.1 3.6 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 CDJ68713.1 - 2.1e-13 50.4 0.1 1.8e-10 41.0 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CDJ68713.1 - 3.1e-07 30.2 0.0 5.2e-06 26.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CDJ68713.1 - 6.4e-07 29.5 0.0 0.043 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CDJ68713.1 - 3.1e-06 27.7 9.2 0.017 15.5 0.2 5.2 3 3 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 CDJ68713.1 - 9e-06 26.0 2.1 0.005 17.1 0.0 4.4 4 1 0 4 4 3 1 AAA domain RuvB_N PF05496.12 CDJ68713.1 - 4.9e-05 23.1 0.1 0.038 13.7 0.0 3.3 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CDJ68713.1 - 8.7e-05 23.1 3.4 0.028 15.0 0.0 4.0 4 1 1 5 5 3 1 AAA domain ATPase_2 PF01637.18 CDJ68713.1 - 0.00015 21.7 0.5 0.28 11.1 0.0 3.3 4 0 0 4 4 3 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CDJ68713.1 - 0.0003 20.3 0.0 0.0063 16.0 0.0 2.4 2 1 0 2 2 2 1 P-loop containing dynein motor region DNA_pol3_delta2 PF13177.6 CDJ68713.1 - 0.0023 17.7 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase III, delta subunit IstB_IS21 PF01695.17 CDJ68713.1 - 0.0059 16.4 0.0 0.14 11.9 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 CDJ68713.1 - 0.0075 15.6 0.2 0.057 12.7 0.0 2.6 3 0 0 3 3 2 1 Zeta toxin AAA_3 PF07726.11 CDJ68713.1 - 0.0087 15.9 0.0 0.36 10.7 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CDJ68713.1 - 0.012 15.0 0.2 3.1 7.1 0.0 3.3 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 CDJ68713.1 - 0.017 14.2 0.0 0.049 12.7 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein Sulfatase_C PF14707.6 CDJ68713.1 - 0.021 15.5 0.1 0.071 13.8 0.1 1.9 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF815 PF05673.13 CDJ68713.1 - 0.024 13.8 0.0 0.43 9.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 CDJ68713.1 - 0.027 14.9 0.0 0.73 10.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 CDJ68713.1 - 0.027 14.7 1.6 5.9 7.1 0.0 4.1 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CDJ68713.1 - 0.032 14.8 0.0 0.22 12.0 0.0 2.5 3 0 0 3 3 1 0 ABC transporter RsgA_GTPase PF03193.16 CDJ68713.1 - 0.039 13.8 0.4 1.3 8.9 0.0 3.4 4 1 0 4 4 4 0 RsgA GTPase AAA_17 PF13207.6 CDJ68713.1 - 0.075 13.4 0.2 2.7 8.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF4407 PF14362.6 CDJ68713.1 - 0.098 12.0 6.7 0.22 10.9 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TsaE PF02367.17 CDJ68713.1 - 0.1 12.6 0.1 1.3 9.0 0.0 2.8 4 0 0 4 4 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 CDJ68713.1 - 0.11 12.7 0.0 0.59 10.4 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 CDJ68713.1 - 0.12 12.3 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Fmp27_WPPW PF10359.9 CDJ68713.1 - 0.16 10.7 3.5 0.3 9.9 3.5 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF87 PF01935.17 CDJ68713.1 - 0.32 11.1 3.8 2 8.4 0.0 3.4 3 1 0 3 3 3 0 Helicase HerA, central domain phage_tail_N PF08400.10 CDJ68713.1 - 0.42 10.6 1.6 1 9.4 0.3 2.3 3 0 0 3 3 1 0 Prophage tail fibre N-terminal AAA_33 PF13671.6 CDJ68713.1 - 1.5 9.0 4.4 2.6 8.2 0.0 3.4 5 0 0 5 5 2 0 AAA domain AAA_12 PF13087.6 CDJ68714.1 - 2.1e-22 79.7 0.0 2.6e-15 56.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CDJ68714.1 - 8.8e-14 51.7 2.9 7.2e-12 45.4 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CDJ68714.1 - 2e-12 47.5 0.0 5.8e-06 26.3 0.0 2.7 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ68714.1 - 5.5e-09 36.5 1.3 4.8e-08 33.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CDJ68714.1 - 0.00069 20.0 0.8 0.0038 17.6 0.1 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA PF00004.29 CDJ68714.1 - 0.0011 19.4 0.0 0.0036 17.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CDJ68714.1 - 0.0026 17.7 0.0 0.0069 16.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.16 CDJ68714.1 - 0.019 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 CDJ68714.1 - 0.07 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 CDJ68714.1 - 0.09 12.5 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 CDJ68714.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CDJ68714.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain HypA PF01155.19 CDJ68714.1 - 2.5 8.1 5.4 0.37 10.8 0.0 2.4 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LRRNT_2 PF08263.12 CDJ68716.1 - 0.16 12.3 2.1 8 6.9 0.7 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Asn_synthase PF00733.21 CDJ68718.1 - 7.3e-10 39.0 5.3 0.00016 21.5 1.1 3.2 2 1 0 2 2 2 2 Asparagine synthase Lectin_leg-like PF03388.13 CDJ68719.1 - 1.1e-12 47.8 0.2 2.2e-12 46.8 0.2 1.5 1 1 0 1 1 1 1 Legume-like lectin family Got1 PF04178.12 CDJ68720.1 - 8.9e-31 106.6 18.4 1.2e-30 106.2 18.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Kazal_2 PF07648.15 CDJ68721.1 - 6.5e-08 32.6 8.1 1.7e-07 31.3 8.1 1.6 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CDJ68721.1 - 1.3e-07 31.5 6.1 2.1e-07 30.8 6.1 1.3 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Alpha_TIF PF02232.15 CDJ68721.1 - 0.033 13.3 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) Myb_DNA-binding PF00249.31 CDJ68722.1 - 4.1e-18 65.3 14.4 1.5e-11 44.3 1.1 3.7 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ68722.1 - 6.3e-18 64.8 0.1 3.2e-12 46.5 2.0 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_Cef PF11831.8 CDJ68722.1 - 2.1e-17 63.5 4.1 2.1e-17 63.5 4.1 4.1 4 1 0 4 4 4 1 pre-mRNA splicing factor component GSCFA PF08885.11 CDJ68722.1 - 0.019 14.7 0.2 0.043 13.5 0.2 1.6 1 0 0 1 1 1 0 GSCFA family TssC PF17541.2 CDJ68722.1 - 0.039 12.8 0.2 0.1 11.4 0.2 1.6 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Rap1_C PF11626.8 CDJ68722.1 - 0.24 11.5 6.4 0.41 10.8 0.1 3.6 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Phosducin PF02114.16 CDJ68722.1 - 0.49 9.3 4.0 1.1 8.1 4.0 1.5 1 0 0 1 1 1 0 Phosducin Chorein_N PF12624.7 CDJ68723.1 - 4.2e-10 39.8 0.0 1.3e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 CDJ68723.1 - 6.5e-05 22.4 0.0 0.0002 20.8 0.0 1.7 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 CDJ68723.1 - 6.6e-05 22.8 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Na_H_antiporter PF03553.14 CDJ68723.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Na+/H+ antiporter family Ribosomal_L31e PF01198.19 CDJ68724.1 - 5.3e-40 135.5 4.0 5.3e-40 135.5 4.0 1.6 1 1 1 2 2 2 1 Ribosomal protein L31e DUF4890 PF16231.5 CDJ68724.1 - 0.11 13.0 1.3 8.5 6.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) Rep_fac_C PF08542.11 CDJ68725.1 - 2.4e-12 47.1 0.0 6.1e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_assoc_2 PF16193.5 CDJ68725.1 - 0.00024 21.3 0.5 0.00093 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA C-terminal domain DNA_pol3_delta2 PF13177.6 CDJ68725.1 - 0.0098 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 CDJ68726.1 - 1.3e-07 31.9 0.1 2e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CDJ68726.1 - 4.3e-07 29.9 0.1 7.8e-07 29.0 0.1 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CDJ68726.1 - 1.1e-05 25.8 0.1 1.7e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ68726.1 - 2.3e-05 24.2 0.1 2.3e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CDJ68726.1 - 0.0016 18.5 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CDJ68726.1 - 0.0018 17.9 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 CDJ68726.1 - 0.0038 17.6 0.1 0.0086 16.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 CDJ68726.1 - 0.0043 16.7 0.4 0.012 15.3 0.4 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain PhoH PF02562.16 CDJ68726.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein ABC_tran PF00005.27 CDJ68726.1 - 0.012 16.2 0.4 0.62 10.6 0.1 2.2 1 1 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 CDJ68726.1 - 0.016 14.8 0.1 0.047 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 CDJ68726.1 - 0.017 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 CDJ68726.1 - 0.034 14.3 0.0 0.098 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 CDJ68726.1 - 0.039 13.1 0.1 0.067 12.3 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 CDJ68726.1 - 0.04 13.8 0.0 0.092 12.7 0.0 1.6 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.9 CDJ68726.1 - 0.048 12.9 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.9 CDJ68726.1 - 0.063 12.2 0.2 0.095 11.6 0.2 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.6 CDJ68726.1 - 0.13 12.3 0.0 0.81 9.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ68726.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 CDJ68726.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 CDJ68726.1 - 0.29 11.6 0.0 0.54 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 CDJ68728.1 - 0.00042 20.2 0.0 0.0009 19.2 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain TFIIA PF03153.13 CDJ68728.1 - 0.95 9.4 7.6 0.11 12.5 3.6 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CAP_N PF01213.19 CDJ68728.1 - 1.3 8.5 10.1 0.34 10.3 5.7 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Spt20 PF12090.8 CDJ68728.1 - 2.8 7.5 9.3 6.2 6.4 9.3 1.5 1 0 0 1 1 1 0 Spt20 family Myosin_head PF00063.21 CDJ68729.1 - 9.9e-06 24.1 0.0 1.2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_head PF00063.21 CDJ68730.1 - 6.2e-100 335.4 0.0 7.4e-100 335.1 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CDJ68730.1 - 0.031 14.7 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 CDJ68730.1 - 0.04 13.9 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 CDJ68730.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CDJ68730.1 - 0.082 13.2 0.1 0.23 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ68730.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 CDJ68730.1 - 0.16 12.3 0.0 0.71 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Myosin_head PF00063.21 CDJ68731.1 - 1.6e-63 215.1 0.0 2.2e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Dynein_light PF01221.18 CDJ68731.1 - 5.6e-06 26.6 0.2 0.0011 19.2 0.0 3.0 3 0 0 3 3 3 1 Dynein light chain type 1 TRF PF08558.10 CDJ68731.1 - 0.07 12.7 0.2 0.97 9.0 0.0 2.5 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) U1snRNP70_N PF12220.8 CDJ68731.1 - 2.9 8.6 6.9 0.34 11.6 2.5 1.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RNase_T PF00929.24 CDJ68732.1 - 1.5e-07 32.1 0.0 1.7e-06 28.7 0.0 2.2 1 1 0 1 1 1 1 Exonuclease PLAC PF08686.11 CDJ68732.1 - 0.19 12.5 1.1 0.99 10.2 0.7 2.4 2 0 0 2 2 2 0 PLAC (protease and lacunin) domain Macoilin PF09726.9 CDJ68734.1 - 1.9 6.9 9.6 2.6 6.5 9.6 1.2 1 0 0 1 1 1 0 Macoilin family Pex14_N PF04695.13 CDJ68735.1 - 0.041 14.5 1.1 0.041 14.5 1.1 6.4 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UPF0182 PF03699.13 CDJ68735.1 - 0.4 8.7 6.3 0.6 8.2 6.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) BPL_N PF09825.9 CDJ68735.1 - 1.5 7.8 11.7 0.53 9.3 7.9 1.9 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal ANAPC_CDC26 PF10471.9 CDJ68736.1 - 0.92 10.4 24.1 1.4 9.8 24.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Sec62 PF03839.16 CDJ68736.1 - 2.2 7.7 8.6 2.4 7.6 8.6 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 CLN3 PF02487.17 CDJ68736.1 - 3.2 6.7 3.5 3.1 6.8 3.5 1.0 1 0 0 1 1 1 0 CLN3 protein RR_TM4-6 PF06459.12 CDJ68736.1 - 3.3 7.4 9.7 3.3 7.4 9.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 CDJ68736.1 - 8.2 5.7 9.7 11 5.3 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Torus PF16131.5 CDJ68737.1 - 0.0001 22.9 0.6 0.0001 22.9 0.6 3.2 2 1 1 3 3 3 2 Torus domain SUIM_assoc PF16619.5 CDJ68737.1 - 0.028 14.5 8.2 0.42 10.7 0.3 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 CDJ68737.1 - 6.2 5.9 10.4 1.8 7.6 4.3 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal ATP12 PF07542.11 CDJ68738.1 - 7.3e-05 22.8 10.8 0.0013 18.8 7.4 2.9 2 1 0 2 2 2 1 ATP12 chaperone protein DUF4820 PF16091.5 CDJ68738.1 - 0.25 10.7 8.8 0.35 10.2 7.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) HisKA PF00512.25 CDJ68738.1 - 3 7.9 7.7 0.19 11.8 0.4 2.7 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain GST_C_6 PF17171.4 CDJ68739.1 - 0.098 12.5 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1980 PF09323.10 CDJ68739.1 - 0.58 10.0 4.1 3.7 7.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Adaptin_binding PF10199.9 CDJ68739.1 - 2 9.0 11.1 0.34 11.5 4.2 3.0 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4692 PF15763.5 CDJ68739.1 - 3.6 8.0 18.8 3.8 8.0 4.3 3.4 3 0 0 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) EphA2_TM PF14575.6 CDJ68739.1 - 5.8 7.9 6.0 63 4.5 0.1 4.2 5 0 0 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain RskA PF10099.9 CDJ68739.1 - 6.4 7.0 70.2 1.5 9.1 4.0 5.8 2 1 3 5 5 5 0 Anti-sigma-K factor rskA Hid1 PF12722.7 CDJ68740.1 - 0.042 12.0 0.3 0.049 11.8 0.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.14 CDJ68740.1 - 0.34 10.9 1.4 0.42 10.6 1.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Aminotran_1_2 PF00155.21 CDJ68740.1 - 0.56 9.3 4.2 0.9 8.6 4.2 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Apt1 PF10351.9 CDJ68740.1 - 1.2 7.9 7.1 1.3 7.8 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 CDJ68740.1 - 9.1 4.8 9.7 9.7 4.7 9.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 CDJ68740.1 - 9.4 4.8 9.5 10 4.6 9.5 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4386 PF14329.6 CDJ68741.1 - 0.018 14.9 5.9 0.021 14.7 5.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Shadoo PF14999.6 CDJ68741.1 - 0.028 14.5 11.0 0.03 14.4 11.0 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Dehydrin PF00257.19 CDJ68741.1 - 0.032 14.8 4.3 0.034 14.7 4.3 1.0 1 0 0 1 1 1 0 Dehydrin SUIM_assoc PF16619.5 CDJ68741.1 - 1.1 9.4 9.1 1.3 9.1 9.1 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 R_equi_Vir PF05526.11 CDJ68741.1 - 1.1 9.0 7.2 1.2 8.9 7.2 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RskA PF10099.9 CDJ68741.1 - 2 8.7 22.5 2.5 8.4 22.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA FAM199X PF15814.5 CDJ68741.1 - 2.1 7.3 6.2 2.3 7.2 6.2 1.0 1 0 0 1 1 1 0 Protein family FAM199X DUF4630 PF15443.6 CDJ68741.1 - 2.5 8.3 15.5 3 8.0 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) Tic110 PF16940.5 CDJ68741.1 - 4.2 5.7 10.9 4.5 5.6 10.9 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter TTL PF03133.15 CDJ68742.1 - 0.00056 19.1 0.0 0.00095 18.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Transposase_24 PF03004.14 CDJ68742.1 - 0.74 9.9 8.6 0.79 9.8 3.1 2.5 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) SR-25 PF10500.9 CDJ68742.1 - 2.3 7.8 53.3 0.23 11.0 28.8 2.9 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 CDJ68742.1 - 3.6 8.2 18.6 0.87 10.2 10.4 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4685 PF15737.5 CDJ68742.1 - 5.9 7.3 16.7 5 7.6 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) DUF755 PF05501.11 CDJ68742.1 - 9.8 6.5 35.6 13 6.1 19.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) CDK2AP PF09806.9 CDJ68743.1 - 0.0018 18.4 12.2 0.0018 18.4 12.2 3.4 2 2 1 3 3 3 1 Cyclin-dependent kinase 2-associated protein SUIM_assoc PF16619.5 CDJ68744.1 - 0.034 14.2 0.1 0.034 14.2 0.1 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Miga PF10265.9 CDJ68744.1 - 0.045 12.7 1.2 0.09 11.7 1.2 1.4 1 0 0 1 1 1 0 Mitoguardin TMEM154 PF15102.6 CDJ68744.1 - 0.061 13.2 1.4 0.27 11.1 0.1 2.7 3 1 0 3 3 3 0 TMEM154 protein family DUF4834 PF16118.5 CDJ68744.1 - 0.13 13.2 1.8 7.1 7.7 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ68744.1 - 0.17 9.8 2.0 0.56 8.0 2.0 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family MecA PF05389.12 CDJ68744.1 - 0.67 9.5 3.8 0.28 10.8 0.5 1.8 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF2681 PF10883.8 CDJ68744.1 - 1.2 9.6 17.7 0.78 10.2 1.6 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF4064 PF13273.6 CDJ68744.1 - 2 8.7 0.0 2 8.7 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF4064) Sugar_tr PF00083.24 CDJ68745.1 - 3.4e-14 52.6 40.1 1.8e-12 46.8 6.3 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 CDJ68745.1 - 2.8e-05 23.2 49.3 2.8e-05 23.2 49.3 4.1 2 2 1 3 3 3 2 Major Facilitator Superfamily Apt1 PF10351.9 CDJ68745.1 - 1.1 8.0 2.5 2.3 7.0 2.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain SUIM_assoc PF16619.5 CDJ68746.1 - 0.0016 18.4 3.8 0.0016 18.4 3.8 12.4 7 2 1 8 8 8 2 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ68746.1 - 0.019 13.9 0.2 0.019 13.9 0.2 8.0 4 2 3 7 7 7 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ68747.1 - 0.014 15.1 14.8 0.018 14.6 14.8 1.2 1 0 0 1 1 1 0 Spt20 family Macoilin PF09726.9 CDJ68747.1 - 0.083 11.4 12.4 0.11 11.1 12.4 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ68747.1 - 0.27 10.1 14.0 0.29 9.9 14.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain KASH PF10541.9 CDJ68747.1 - 0.73 10.1 3.6 0.66 10.3 2.1 1.7 2 0 0 2 2 2 0 Nuclear envelope localisation domain PAP1 PF08601.10 CDJ68747.1 - 0.8 9.4 19.3 0.98 9.1 19.3 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 SPX PF03105.19 CDJ68747.1 - 1.9 8.3 16.5 2.2 8.1 16.5 1.2 1 0 0 1 1 1 0 SPX domain Roughex PF06020.11 CDJ68747.1 - 4.9 6.1 8.1 8.3 5.4 8.1 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Mcm10 PF09332.11 CDJ68747.1 - 5.6 6.3 12.4 7.8 5.8 12.4 1.2 1 0 0 1 1 1 0 Mcm10 replication factor NST1 PF13945.6 CDJ68747.1 - 5.7 7.0 9.8 9 6.4 9.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Lin-8 PF03353.15 CDJ68747.1 - 6.6 6.2 11.3 11 5.4 11.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ68748.1 - 4.2e-06 26.6 14.2 6e-06 26.0 14.2 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ68748.1 - 0.013 15.8 13.9 0.013 15.8 13.9 1.6 2 0 0 2 2 2 0 Early growth response N-terminal domain CCSAP PF15748.5 CDJ68748.1 - 0.014 15.6 16.0 0.016 15.4 16.0 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated AF-4 PF05110.13 CDJ68748.1 - 0.061 11.4 22.1 0.065 11.3 22.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TCP PF03634.13 CDJ68748.1 - 0.077 13.5 18.1 0.089 13.4 18.1 1.0 1 0 0 1 1 1 0 TCP family transcription factor FlxA PF14282.6 CDJ68748.1 - 0.22 11.5 52.4 0.28 11.2 52.4 1.1 1 0 0 1 1 1 0 FlxA-like protein NPR3 PF03666.13 CDJ68748.1 - 0.25 10.1 12.7 0.31 9.8 12.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RyR PF02026.16 CDJ68748.1 - 0.3 11.3 5.4 0.22 11.7 3.7 1.7 1 1 0 1 1 1 0 RyR domain IMUP PF15761.5 CDJ68748.1 - 0.38 11.5 12.6 0.058 14.1 9.0 1.6 2 0 0 2 2 1 0 Immortalisation up-regulated protein RAP1 PF07218.11 CDJ68748.1 - 0.65 8.2 4.2 0.6 8.3 4.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAM199X PF15814.5 CDJ68748.1 - 0.85 8.6 13.0 1 8.4 13.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X Dsh_C PF12316.8 CDJ68748.1 - 0.93 9.9 18.3 1 9.7 18.3 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal STAC2_u1 PF16664.5 CDJ68748.1 - 0.97 9.9 14.8 1.3 9.5 14.8 1.2 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 GET2 PF08690.10 CDJ68748.1 - 1.4 8.6 17.2 1.7 8.2 17.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Velvet PF11754.8 CDJ68748.1 - 2.3 8.1 18.2 2.7 7.9 18.2 1.1 1 0 0 1 1 1 0 Velvet factor O-antigen_lig PF13425.6 CDJ68748.1 - 3.7 6.2 4.8 4.2 6.1 4.8 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Phage_GPO PF05929.11 CDJ68748.1 - 4.6 6.8 14.9 4.9 6.7 14.9 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Activator_LAG-3 PF11498.8 CDJ68748.1 - 5.3 5.9 42.4 6.5 5.6 42.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4407 PF14362.6 CDJ68748.1 - 5.5 6.3 15.9 6.3 6.1 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ68748.1 - 5.7 6.8 35.4 8.1 6.3 35.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 CDJ68748.1 - 6.1 5.1 10.2 7.5 4.8 10.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ68748.1 - 7.4 5.4 8.3 11 4.8 8.3 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) PRP1_N PF06424.12 CDJ68748.1 - 7.8 6.9 17.7 1e+02 3.2 17.7 1.9 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal PAT1 PF09770.9 CDJ68748.1 - 8.2 4.6 23.6 8.9 4.4 23.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SUIM_assoc PF16619.5 CDJ68749.1 - 0.019 15.0 5.3 0.019 15.0 5.3 3.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4710 PF15828.5 CDJ68749.1 - 0.033 14.3 3.2 0.82 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) DUF4484 PF14831.6 CDJ68749.1 - 0.09 12.8 4.7 0.14 12.2 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) CIAPIN1 PF05093.13 CDJ68749.1 - 0.77 10.3 8.8 7.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Spt20 PF12090.8 CDJ68749.1 - 1.1 8.8 37.4 0.1 12.2 4.4 2.1 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 CDJ68749.1 - 3.4 6.3 5.4 5.1 5.7 5.4 1.1 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ68750.1 - 8.4e-06 25.0 4.4 1e-05 24.7 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ68750.1 - 0.0013 19.4 16.8 0.0013 19.4 16.8 3.1 3 2 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region COX4 PF02936.14 CDJ68750.1 - 0.045 13.8 0.3 0.045 13.8 0.3 2.2 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV Activator_LAG-3 PF11498.8 CDJ68750.1 - 0.21 10.5 25.6 0.29 10.0 25.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ68750.1 - 0.61 9.7 24.9 0.82 9.2 24.9 1.1 1 0 0 1 1 1 0 Spt20 family V_ATPase_I PF01496.19 CDJ68750.1 - 0.86 7.4 3.0 1.1 7.1 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 CDJ68750.1 - 2.4 6.8 15.7 0.011 14.5 6.3 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 CDJ68750.1 - 2.7 5.0 6.8 3.5 4.6 6.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ68750.1 - 4 5.6 16.2 5.1 5.2 16.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Shisa PF13908.6 CDJ68750.1 - 9.4 6.4 10.1 24 5.1 10.1 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Spt20 PF12090.8 CDJ68751.1 - 0.27 10.8 10.1 0.4 10.3 10.1 1.3 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 CDJ68752.1 - 7e-28 97.7 0.0 2.7e-14 53.2 0.0 3.2 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ68752.1 - 2.5e-11 43.4 0.0 1.2e-06 28.0 0.0 2.4 3 0 0 3 3 2 2 Protein tyrosine kinase DUF1645 PF07816.11 CDJ68752.1 - 0.0034 18.0 24.1 0.11 13.1 18.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1645) Kdo PF06293.14 CDJ68752.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4667 PF15700.5 CDJ68752.1 - 0.029 14.5 23.6 2.3 8.2 19.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ68752.1 - 0.097 12.7 31.7 0.081 12.9 25.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ68752.1 - 0.13 11.9 49.1 0.038 13.6 25.4 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein APH PF01636.23 CDJ68752.1 - 0.23 11.4 0.1 0.23 11.4 0.1 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family PepSY_TM PF03929.16 CDJ68752.1 - 0.26 10.9 4.1 0.31 10.7 0.5 2.3 2 0 0 2 2 2 0 PepSY-associated TM region SLC12 PF03522.15 CDJ68752.1 - 0.26 10.3 8.6 0.41 9.6 8.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Spt20 PF12090.8 CDJ68752.1 - 0.34 10.5 34.2 0.66 9.5 34.2 1.4 1 0 0 1 1 1 0 Spt20 family FAM176 PF14851.6 CDJ68752.1 - 3.5 7.3 8.1 8 6.1 8.1 1.6 1 0 0 1 1 1 0 FAM176 family CLN3 PF02487.17 CDJ68752.1 - 3.9 6.4 7.9 7 5.6 7.9 1.4 1 0 0 1 1 1 0 CLN3 protein Cwf_Cwc_15 PF04889.12 CDJ68752.1 - 4.4 6.9 18.2 0.096 12.4 11.6 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein eIF-3_zeta PF05091.12 CDJ68752.1 - 5.6 5.8 14.0 7.9 5.3 14.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BRF1 PF07741.13 CDJ68752.1 - 6.8 7.1 12.6 0.3 11.4 6.8 1.7 2 0 0 2 2 1 0 Brf1-like TBP-binding domain Filament_head PF04732.14 CDJ68752.1 - 7.4 7.5 32.7 13 6.7 8.4 2.5 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Roughex PF06020.11 CDJ68752.1 - 8.1 5.4 14.6 13 4.7 14.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Afi1 PF07792.12 CDJ68752.1 - 8.8 6.8 12.8 6.5 7.3 10.9 1.7 2 0 0 2 2 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Tim54 PF11711.8 CDJ68752.1 - 8.9 5.0 9.9 14 4.4 9.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SURF6 PF04935.12 CDJ68752.1 - 9.1 6.0 18.8 0.72 9.6 13.7 1.7 2 0 0 2 2 2 0 Surfeit locus protein 6 RRM_1 PF00076.22 CDJ68753.1 - 1e-53 179.0 0.0 6.6e-18 64.3 0.0 8.6 8 0 0 8 8 8 7 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ68753.1 - 1.2e-09 37.8 0.0 0.05 13.2 0.0 5.3 4 1 1 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WASH-7_C PF14746.6 CDJ68753.1 - 0.00097 18.9 5.4 0.00097 18.9 5.4 4.0 4 1 0 4 4 4 1 WASH complex subunit 7, C-terminal DUF2722 PF10846.8 CDJ68753.1 - 0.0049 15.9 15.2 0.0049 15.9 15.2 4.1 4 1 0 4 4 4 2 Protein of unknown function (DUF2722) Smg4_UPF3 PF03467.15 CDJ68753.1 - 0.016 15.2 0.0 0.016 15.2 0.0 5.6 5 0 0 5 5 5 0 Smg-4/UPF3 family RRM_occluded PF16842.5 CDJ68753.1 - 0.018 14.9 8.7 4 7.4 0.1 5.0 6 0 0 6 6 6 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CDJ68753.1 - 0.058 13.4 0.7 2.6 8.1 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Eapp_C PF10238.9 CDJ68753.1 - 0.18 11.9 31.1 1.6 8.8 4.3 4.2 3 0 0 3 3 3 0 E2F-associated phosphoprotein SpoIIP PF07454.11 CDJ68753.1 - 0.18 11.2 27.2 0.25 10.8 4.2 3.4 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) DUF4770 PF15994.5 CDJ68753.1 - 1.9 8.7 42.6 2.2 8.5 10.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) LRR_4 PF12799.7 CDJ68754.1 - 5e-13 49.0 14.2 0.00018 21.8 1.6 5.0 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ68754.1 - 2.5e-11 43.2 8.8 5.5e-05 22.8 0.4 5.3 4 1 1 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 CDJ68754.1 - 3.5e-06 26.6 2.8 2.7 8.3 0.3 5.8 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.6 CDJ68754.1 - 9.5e-05 22.0 6.3 0.081 12.4 0.1 3.7 4 0 0 4 4 3 1 Leucine-rich repeat MecA PF05389.12 CDJ68754.1 - 0.0051 16.5 4.1 1.3 8.6 2.2 2.3 2 0 0 2 2 2 2 Negative regulator of genetic competence (MecA) EPL1 PF10513.9 CDJ68754.1 - 0.016 15.6 3.6 0.016 15.6 3.6 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like RNase_H2_suC PF08615.11 CDJ68754.1 - 0.021 15.0 1.2 1.5 9.0 0.4 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Spt20 PF12090.8 CDJ68754.1 - 0.023 14.3 48.3 0.1 12.2 28.0 2.4 2 0 0 2 2 2 0 Spt20 family LRR_1 PF00560.33 CDJ68754.1 - 0.027 15.0 11.5 55 4.9 0.2 5.9 6 0 0 6 6 5 0 Leucine Rich Repeat MID_MedPIWI PF18296.1 CDJ68754.1 - 0.042 13.6 9.4 1.9 8.2 5.0 2.4 2 0 0 2 2 2 0 MID domain of medPIWI RskA PF10099.9 CDJ68754.1 - 0.056 13.7 75.4 8.5e+02 0.1 27.5 4.6 1 1 1 2 2 2 0 Anti-sigma-K factor rskA RPA43_OB PF17875.1 CDJ68754.1 - 0.065 13.9 5.8 4.8 7.8 2.5 2.7 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I MMR1 PF08505.10 CDJ68754.1 - 0.085 13.1 13.9 0.34 11.2 6.9 2.4 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 CDJ68754.1 - 0.11 11.2 13.7 0.62 8.8 9.7 2.2 2 0 0 2 2 2 0 Presenilin Plasmodium_Vir PF05795.11 CDJ68754.1 - 0.21 11.0 2.2 0.89 8.9 0.7 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein EOS1 PF12326.8 CDJ68754.1 - 0.21 11.5 2.7 3.8 7.4 1.9 2.2 2 0 0 2 2 2 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ68754.1 - 0.22 10.5 16.9 0.19 10.7 8.7 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ68754.1 - 0.24 12.4 21.9 1.6 9.8 12.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ68754.1 - 0.28 11.1 16.5 1.2 9.1 0.5 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ68754.1 - 0.31 11.1 7.2 1.1 9.2 4.3 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MH2 PF03166.14 CDJ68754.1 - 0.31 11.3 3.8 11 6.3 0.8 2.3 2 0 0 2 2 2 0 MH2 domain CAF1 PF04857.20 CDJ68754.1 - 0.43 9.7 4.9 9 5.4 2.5 2.1 2 0 0 2 2 2 0 CAF1 family ribonuclease DUF2722 PF10846.8 CDJ68754.1 - 0.44 9.4 38.4 0.076 11.9 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) FAM60A PF15396.6 CDJ68754.1 - 0.48 10.4 4.3 2.3 8.2 2.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF5523 PF17661.1 CDJ68754.1 - 0.49 10.0 10.2 5.2 6.7 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Fer4_18 PF13746.6 CDJ68754.1 - 0.51 10.5 5.6 2.4 8.4 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain FAM176 PF14851.6 CDJ68754.1 - 0.63 9.7 7.4 0.44 10.2 1.6 2.3 2 0 0 2 2 2 0 FAM176 family Peptidase_S49_N PF08496.10 CDJ68754.1 - 0.7 9.9 8.7 3.7 7.6 5.3 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TFIIA PF03153.13 CDJ68754.1 - 0.75 9.7 61.3 0.21 11.5 9.1 2.3 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1980 PF09323.10 CDJ68754.1 - 0.98 9.3 4.7 4.8 7.1 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Eapp_C PF10238.9 CDJ68754.1 - 1.3 9.1 16.0 1.5 8.9 7.3 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein SLC12 PF03522.15 CDJ68754.1 - 1.5 7.8 10.4 0.59 9.1 4.6 2.3 3 0 0 3 3 3 0 Solute carrier family 12 DUF3381 PF11861.8 CDJ68754.1 - 1.6 8.5 16.4 0.68 9.7 6.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) SpoIIP PF07454.11 CDJ68754.1 - 2.1 7.7 14.1 1.3 8.4 6.2 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) MAM33 PF02330.16 CDJ68754.1 - 2.3 8.1 11.9 3 7.7 3.5 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein Utp14 PF04615.13 CDJ68754.1 - 2.8 6.4 19.2 4 5.9 16.2 2.0 2 0 0 2 2 2 0 Utp14 protein Peroxin-13_N PF04088.13 CDJ68754.1 - 3 8.1 6.3 17 5.7 3.5 2.5 2 0 0 2 2 2 0 Peroxin 13, N-terminal region EFTUD2 PF16004.5 CDJ68754.1 - 4.1 8.0 18.3 2 9.0 1.0 2.5 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Connexin PF00029.19 CDJ68754.1 - 6.4 6.5 9.5 57 3.3 7.6 2.3 2 0 0 2 2 2 0 Connexin Baculo_PP31 PF05311.11 CDJ68754.1 - 7.8 5.9 13.2 0.9 9.0 6.9 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) ALMT PF11744.8 CDJ68754.1 - 8.6 5.1 11.5 2.6 6.8 7.1 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter LIM_bind PF01803.16 CDJ68754.1 - 8.7 5.8 13.1 17 4.8 0.2 2.3 2 0 0 2 2 2 0 LIM-domain binding protein Afi1 PF07792.12 CDJ68754.1 - 8.9 6.8 14.1 19 5.8 0.4 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF572 PF04502.13 CDJ68754.1 - 9.7 5.7 14.0 15 5.1 9.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) AP2 PF00847.20 CDJ68755.1 - 0.072 13.3 0.1 0.072 13.3 0.1 3.6 4 0 0 4 4 4 0 AP2 domain Mitofilin PF09731.9 CDJ68755.1 - 0.18 10.6 6.1 0.25 10.1 6.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FAM220 PF15487.6 CDJ68755.1 - 0.22 11.2 0.3 0.36 10.4 0.3 1.3 1 0 0 1 1 1 0 FAM220 family Dus PF01207.17 CDJ68756.1 - 3.2e-12 46.2 0.1 4e-11 42.6 0.0 2.4 3 0 0 3 3 3 1 Dihydrouridine synthase (Dus) DUF3446 PF11928.8 CDJ68756.1 - 1.2e-06 28.7 20.3 0.00056 20.1 10.9 2.7 2 0 0 2 2 2 2 Early growth response N-terminal domain MID_MedPIWI PF18296.1 CDJ68756.1 - 0.0031 17.4 1.8 0.013 15.3 1.8 1.9 1 1 0 1 1 1 1 MID domain of medPIWI DUF1645 PF07816.11 CDJ68756.1 - 0.01 16.4 9.9 0.025 15.2 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF4667 PF15700.5 CDJ68756.1 - 0.014 15.6 8.7 0.032 14.3 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ68756.1 - 0.069 13.1 1.1 0.088 12.7 1.1 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ68756.1 - 0.19 10.6 0.9 0.26 10.1 0.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAM-associated PF14303.6 CDJ68756.1 - 3.5 8.3 8.1 6 7.6 0.1 2.6 3 0 0 3 3 3 0 No apical meristem-associated C-terminal domain SR-25 PF10500.9 CDJ68756.1 - 8.4 5.9 41.1 0.21 11.2 6.9 2.9 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Serglycin PF04360.12 CDJ68756.1 - 9.5 6.1 9.1 16 5.4 0.3 2.2 2 0 0 2 2 2 0 Serglycin ACPS PF01648.20 CDJ68757.1 - 6e-13 48.9 0.0 1.7e-12 47.5 0.0 1.8 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Nup54 PF13874.6 CDJ68757.1 - 0.062 13.4 0.8 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 TipAS PF07739.13 CDJ68757.1 - 0.19 12.3 2.9 4.5 7.9 1.5 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain GDPD PF03009.17 CDJ68758.1 - 1.6e-05 24.8 0.0 0.00015 21.6 0.0 2.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SR-25 PF10500.9 CDJ68758.1 - 0.66 9.5 16.4 0.95 9.0 16.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1180 PF06679.12 CDJ68760.1 - 1.3 9.4 10.8 0.57 10.6 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Ribosomal_60s PF00428.19 CDJ68760.1 - 1.8 9.2 21.8 0.38 11.4 2.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ68760.1 - 4.8 7.5 19.1 0.83 9.9 4.0 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA AP2 PF00847.20 CDJ68762.1 - 9.6e-05 22.5 0.3 0.00043 20.5 0.3 2.2 1 0 0 1 1 1 1 AP2 domain PNISR PF15996.5 CDJ68762.1 - 0.018 15.3 1.9 0.018 15.3 1.9 3.5 3 1 0 3 3 3 0 Arginine/serine-rich protein PNISR DnaJ-X PF14308.6 CDJ68763.1 - 5.4e-48 163.2 11.8 5.4e-48 163.2 11.8 3.6 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 CDJ68763.1 - 5.5e-25 87.3 0.6 1.3e-24 86.1 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain Chorion_2 PF03964.15 CDJ68763.1 - 0.041 14.7 0.3 0.041 14.7 0.3 7.3 4 2 2 6 6 6 0 Chorion family 2 LUC7 PF03194.15 CDJ68764.1 - 2.9e-41 141.8 0.9 3.9e-41 141.4 0.9 1.1 1 0 0 1 1 1 1 LUC7 N_terminus Exonuc_VII_L PF02601.15 CDJ68764.1 - 0.0048 16.5 0.7 0.0059 16.2 0.7 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Meth_synt_2 PF01717.18 CDJ68764.1 - 0.0076 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain HOOK PF05622.12 CDJ68764.1 - 0.029 12.5 4.0 0.037 12.2 4.0 1.1 1 0 0 1 1 1 0 HOOK protein Occludin_ELL PF07303.13 CDJ68764.1 - 0.031 15.0 4.6 0.15 12.8 4.1 2.0 1 1 1 2 2 2 0 Occludin homology domain DUF603 PF04645.12 CDJ68764.1 - 0.033 13.9 0.5 0.079 12.7 0.4 1.6 1 1 1 2 2 2 0 Protein of unknown function, DUF603 SRP-alpha_N PF04086.13 CDJ68764.1 - 0.035 14.0 1.0 0.043 13.7 1.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2357 PF09823.9 CDJ68764.1 - 0.035 13.4 1.5 0.052 12.8 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) FCD PF07729.12 CDJ68764.1 - 0.038 14.4 0.5 0.084 13.3 0.5 1.6 1 0 0 1 1 1 0 FCD domain NPV_P10 PF05531.12 CDJ68764.1 - 0.046 14.2 3.5 4.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IML1 PF12257.8 CDJ68764.1 - 0.087 11.9 0.2 0.32 10.1 0.1 1.7 2 0 0 2 2 2 0 Vacuolar membrane-associated protein Iml1 Ran-binding PF05508.11 CDJ68764.1 - 0.095 11.7 1.3 0.14 11.1 1.3 1.2 1 0 0 1 1 1 0 RanGTP-binding protein ADIP PF11559.8 CDJ68764.1 - 0.11 12.6 5.4 0.39 10.8 2.3 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DASH_Spc19 PF08287.11 CDJ68764.1 - 0.13 12.1 3.7 0.2 11.5 3.7 1.3 1 0 0 1 1 1 0 Spc19 Imm51 PF15595.6 CDJ68764.1 - 0.17 11.9 1.2 6.4 6.8 0.1 2.3 1 1 0 2 2 2 0 Immunity protein 51 DASH_Dad4 PF08650.10 CDJ68764.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.7 2 1 0 2 2 2 0 DASH complex subunit Dad4 DUF948 PF06103.11 CDJ68764.1 - 0.22 11.8 0.7 5.9 7.2 0.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Rho_Binding PF08912.11 CDJ68764.1 - 0.23 12.3 4.6 24 5.8 0.0 2.4 2 0 0 2 2 2 0 Rho Binding ABC_tran_CTD PF16326.5 CDJ68764.1 - 0.28 11.4 5.4 0.38 11.0 3.6 2.0 1 1 2 3 3 3 0 ABC transporter C-terminal domain HSCB_C PF07743.13 CDJ68764.1 - 0.35 11.4 6.2 5.6 7.5 6.2 2.6 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain TMF_TATA_bd PF12325.8 CDJ68764.1 - 0.49 10.6 7.0 4 7.7 4.3 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 CDJ68764.1 - 0.7 10.6 5.4 38 5.0 0.0 2.6 2 1 0 2 2 2 0 SlyX GIT_CC PF16559.5 CDJ68764.1 - 0.72 9.8 4.0 0.86 9.5 0.0 2.6 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 CDJ68764.1 - 1.6 8.9 12.8 13 6.0 0.1 3.2 3 0 0 3 3 3 0 Basic region leucine zipper V_ATPase_I PF01496.19 CDJ68764.1 - 1.9 6.3 3.9 3 5.7 3.9 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.6 CDJ68764.1 - 2.2 8.6 7.5 5.7 7.3 4.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ZapB PF06005.12 CDJ68764.1 - 6.1 7.4 9.2 3.2 8.2 0.0 2.5 2 1 0 2 2 2 0 Cell division protein ZapB Mst1_SARAH PF11629.8 CDJ68764.1 - 8.4 6.6 7.6 0.47 10.6 0.4 2.4 3 0 0 3 3 2 0 C terminal SARAH domain of Mst1 Secretin_N_2 PF07655.13 CDJ68765.1 - 0.0052 17.3 13.4 0.092 13.3 0.4 2.5 2 0 0 2 2 2 2 Secretin N-terminal domain SR-25 PF10500.9 CDJ68765.1 - 0.0074 15.9 40.0 0.033 13.8 16.5 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF4667 PF15700.5 CDJ68765.1 - 0.011 15.8 16.9 0.31 11.1 10.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Lin-8 PF03353.15 CDJ68765.1 - 0.054 13.1 5.2 0.063 12.8 2.0 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF1645 PF07816.11 CDJ68765.1 - 0.075 13.6 15.5 0.55 10.8 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) SUZ PF12752.7 CDJ68765.1 - 0.37 11.6 9.8 5 8.0 0.4 2.5 2 0 0 2 2 2 0 SUZ domain IMUP PF15761.5 CDJ68765.1 - 0.43 11.3 29.5 0.22 12.2 8.9 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein FAM104 PF15434.6 CDJ68765.1 - 0.67 10.5 13.8 3.2 8.3 5.5 2.3 2 0 0 2 2 2 0 Family 104 EBP50_C PF09007.11 CDJ68765.1 - 1.2 10.2 11.2 2.1 9.3 4.9 2.3 2 0 0 2 2 2 0 EBP50, C-terminal CCDC24 PF15669.5 CDJ68765.1 - 2.5 7.9 10.3 5.3 6.9 0.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family DUF3774 PF12609.8 CDJ68765.1 - 4.6 8.3 9.1 9 7.4 3.9 2.4 2 0 0 2 2 2 0 Wound-induced protein CDK2AP PF09806.9 CDJ68765.1 - 5.7 6.9 11.1 12 5.9 5.5 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Herpes_UL73 PF03554.13 CDJ68766.1 - 0.13 12.3 0.2 0.25 11.3 0.1 1.6 1 1 1 2 2 2 0 UL73 viral envelope glycoprotein DUF1180 PF06679.12 CDJ68766.1 - 0.18 12.2 1.7 0.29 11.5 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) OmpH PF03938.14 CDJ68767.1 - 0.097 13.0 20.2 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2098 PF09871.9 CDJ68767.1 - 0.11 12.9 2.0 0.28 11.5 2.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Zip PF02535.22 CDJ68767.1 - 0.77 8.9 8.9 1.1 8.4 0.3 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CDJ68767.1 - 1 9.4 5.8 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region HU-CCDC81_bac_2 PF18175.1 CDJ68767.1 - 2.1 8.3 7.3 4.8 7.1 0.1 2.6 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 MAS20 PF02064.15 CDJ68767.1 - 2.9 8.0 9.4 4.8 7.3 7.8 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor Exonuc_VII_L PF02601.15 CDJ68767.1 - 2.9 7.4 10.7 6.6 6.2 5.8 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4746 PF15928.5 CDJ68767.1 - 3.1 7.2 5.7 5.4 6.3 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PRKG1_interact PF15898.5 CDJ68767.1 - 7.5 7.5 18.6 0.67 10.9 5.2 3.0 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain Sid-5 PF17204.3 CDJ68768.1 - 0.28 11.4 2.0 4.6 7.5 0.3 2.2 2 0 0 2 2 2 0 Sid-5 family Herpes_capsid PF06112.11 CDJ68768.1 - 8.8 6.4 13.9 12 6.0 13.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ubiquitin PF00240.23 CDJ68771.1 - 8e-18 64.0 0.1 8.8e-18 63.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ68771.1 - 9e-08 31.8 0.1 1.1e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ68771.1 - 4.8e-05 23.7 0.4 0.00017 22.0 0.4 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 CDJ68771.1 - 0.0041 17.6 0.0 0.0047 17.5 0.0 1.0 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ68771.1 - 0.019 15.3 0.1 0.019 15.3 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain SAGA-Tad1 PF12767.7 CDJ68772.1 - 0.79 9.4 16.9 0.96 9.1 16.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SOBP PF15279.6 CDJ68772.1 - 0.8 10.3 16.8 0.95 10.0 16.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Tho2 PF11262.8 CDJ68772.1 - 1.1 8.4 10.1 1.4 8.0 10.1 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 MCM_bind PF09739.9 CDJ68772.1 - 1.1 7.6 12.6 1.3 7.4 12.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF572 PF04502.13 CDJ68772.1 - 1.9 8.0 18.8 2.4 7.7 18.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Draxin PF15550.6 CDJ68772.1 - 2.1 8.1 18.6 2.6 7.8 18.6 1.2 1 0 0 1 1 1 0 Draxin SLC12 PF03522.15 CDJ68772.1 - 3.7 6.5 12.3 4.3 6.3 12.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 V_ATPase_I PF01496.19 CDJ68772.1 - 4.1 5.2 8.6 4.2 5.1 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_Gp23 PF10669.9 CDJ68772.1 - 8.6 6.7 8.5 14 6.1 8.5 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Zip PF02535.22 CDJ68772.1 - 9.3 5.4 8.6 11 5.1 8.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter ALMT PF11744.8 CDJ68772.1 - 9.9 4.9 12.7 12 4.6 12.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_M16 PF00675.20 CDJ68774.1 - 6.6e-05 22.9 4.8 0.00064 19.7 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) eIF-3_zeta PF05091.12 CDJ68774.1 - 0.26 10.2 9.7 0.38 9.7 9.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.17 CDJ68774.1 - 8.7 6.4 8.9 0.31 11.2 1.7 2.2 3 0 0 3 3 3 0 DDHD domain DAHP_synth_2 PF01474.16 CDJ68775.1 - 3e-49 167.7 0.0 4e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF4667 PF15700.5 CDJ68775.1 - 0.015 15.4 23.1 0.21 11.7 11.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) ANAPC1 PF12859.7 CDJ68775.1 - 1.1 9.8 17.7 1.3 9.6 7.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Secretin_N_2 PF07655.13 CDJ68775.1 - 5.4 7.6 31.1 8.9 6.9 19.7 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Thioredoxin PF00085.20 CDJ68776.1 - 5e-14 52.1 0.0 5.2e-06 26.4 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 CDJ68776.1 - 1.1e-08 35.2 0.0 5.6e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Spt20 PF12090.8 CDJ68777.1 - 0.00016 21.4 43.4 0.028 14.0 18.1 2.2 2 0 0 2 2 2 2 Spt20 family DUF4834 PF16118.5 CDJ68777.1 - 0.057 14.4 3.5 0.057 14.4 3.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) SR-25 PF10500.9 CDJ68777.1 - 3.2 7.3 35.3 0.091 12.4 16.8 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein AMP-binding PF00501.28 CDJ68777.1 - 7.5 5.0 9.1 0.64 8.5 0.7 1.9 1 1 1 2 2 2 0 AMP-binding enzyme Connexin PF00029.19 CDJ68777.1 - 7.8 6.2 10.8 3.3 7.4 1.5 2.1 2 0 0 2 2 2 0 Connexin Aminotran_1_2 PF00155.21 CDJ68778.1 - 5.1e-54 183.8 0.0 1.1e-48 166.3 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II SPX PF03105.19 CDJ68779.1 - 1.9e-05 24.8 23.8 0.003 17.5 0.0 2.2 1 1 0 2 2 2 1 SPX domain Apt1 PF10351.9 CDJ68779.1 - 0.00073 18.5 29.7 0.015 14.1 1.4 2.5 2 1 0 2 2 2 2 Golgi-body localisation protein domain Mem_trans PF03547.18 CDJ68779.1 - 0.012 14.0 5.6 5.6 5.3 0.0 2.4 2 1 0 2 2 2 0 Membrane transport protein Pkinase_fungal PF17667.1 CDJ68779.1 - 0.02 13.7 6.2 0.41 9.4 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase RSN1_TM PF13967.6 CDJ68779.1 - 0.097 12.4 0.7 0.25 11.1 0.7 1.8 1 1 0 1 1 1 0 Late exocytosis, associated with Golgi transport Ctr PF04145.15 CDJ68779.1 - 0.67 10.6 13.5 5.1 7.7 0.0 3.5 2 1 0 2 2 2 0 Ctr copper transporter family DUF4808 PF16066.5 CDJ68779.1 - 1.3 9.6 7.6 0.14 12.7 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) Presenilin PF01080.17 CDJ68779.1 - 3.3 6.4 19.8 1.8 7.2 10.3 2.4 2 0 0 2 2 2 0 Presenilin MID_MedPIWI PF18296.1 CDJ68779.1 - 6.8 6.4 22.8 1.3 8.7 11.7 2.8 2 1 0 2 2 2 0 MID domain of medPIWI Cwf_Cwc_15 PF04889.12 CDJ68779.1 - 7.4 6.2 19.6 1.1 9.0 5.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RP-C_C PF11800.8 CDJ68779.1 - 9 6.3 10.8 11 6.0 5.0 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region Neur_chan_memb PF02932.16 CDJ68779.1 - 9.3 6.2 11.3 0.65 10.0 0.2 2.7 2 1 1 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 CDJ68780.1 - 0.019 14.6 7.3 0.015 14.9 7.3 1.1 1 0 0 1 1 1 0 Spt20 family JUPITER PF17054.5 CDJ68780.1 - 0.028 13.9 0.1 0.36 10.3 0.1 2.1 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter DUF533 PF04391.12 CDJ68780.1 - 0.029 13.9 2.1 0.035 13.7 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Androgen_recep PF02166.16 CDJ68780.1 - 0.25 10.1 21.5 0.29 9.9 21.5 1.1 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 CDJ68780.1 - 0.5 10.3 9.8 0.49 10.3 9.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 CDJ68780.1 - 0.75 9.4 6.9 0.84 9.2 6.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2076 PF09849.9 CDJ68780.1 - 2.4 8.1 16.9 2.5 8.1 16.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FAM199X PF15814.5 CDJ68781.1 - 0.033 13.3 0.5 0.039 13.0 0.5 1.1 1 0 0 1 1 1 0 Protein family FAM199X Enterotoxin_a PF01375.17 CDJ68781.1 - 0.23 11.0 3.2 0.27 10.8 3.2 1.0 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain Med3 PF11593.8 CDJ68781.1 - 0.31 10.2 11.7 0.35 10.0 11.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 CDJ68781.1 - 0.37 10.8 8.6 0.39 10.7 8.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ68781.1 - 0.61 10.7 15.3 1.1 9.9 15.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3138 PF11336.8 CDJ68781.1 - 8.7 4.8 9.0 11 4.5 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ISP3_C PF18045.1 CDJ68782.1 - 2.3e-42 143.3 0.6 3.2e-42 142.9 0.6 1.2 1 0 0 1 1 1 1 ISP3 C-terminal ISP1_C PF18161.1 CDJ68782.1 - 3.1e-42 142.9 0.4 4.5e-42 142.4 0.4 1.2 1 0 0 1 1 1 1 ISP1 C-terminal Tim54 PF11711.8 CDJ68782.1 - 0.00049 19.0 4.6 0.00057 18.8 4.6 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 RskA PF10099.9 CDJ68782.1 - 0.0096 16.2 3.0 0.014 15.7 3.0 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Methyltrn_RNA_2 PF04013.12 CDJ68782.1 - 0.012 15.4 0.3 0.025 14.3 0.2 1.6 1 1 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase CDC45 PF02724.14 CDJ68782.1 - 0.03 12.6 6.0 0.032 12.5 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 CDJ68782.1 - 0.045 13.9 9.5 0.082 13.1 9.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 CDJ68782.1 - 0.073 13.2 1.5 0.07 13.3 1.5 1.2 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 CDJ68782.1 - 0.15 10.8 7.1 0.17 10.6 7.1 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CDJ68782.1 - 0.15 11.2 2.6 0.16 11.2 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3824 PF12868.7 CDJ68782.1 - 0.21 12.2 13.3 0.32 11.6 13.3 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) NARP1 PF12569.8 CDJ68782.1 - 0.26 10.1 11.6 0.32 9.9 11.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Connexin PF00029.19 CDJ68782.1 - 0.3 10.8 4.2 0.42 10.3 4.2 1.2 1 0 0 1 1 1 0 Connexin DUF2052 PF09747.9 CDJ68782.1 - 0.68 10.0 12.9 1.3 9.1 12.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Ndc1_Nup PF09531.10 CDJ68782.1 - 1 8.0 4.1 1 8.0 4.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF913 PF06025.12 CDJ68782.1 - 1.5 7.7 6.5 2.3 7.1 6.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MAJIN PF15077.6 CDJ68782.1 - 2 8.1 7.6 2.7 7.7 6.4 1.7 2 0 0 2 2 2 0 Membrane-anchored junction protein RNA_polI_A34 PF08208.11 CDJ68782.1 - 2.6 8.1 21.4 5.4 7.0 21.4 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 FAM176 PF14851.6 CDJ68782.1 - 3.2 7.4 8.6 1.1 8.9 5.9 1.6 2 0 0 2 2 2 0 FAM176 family Neur_chan_memb PF02932.16 CDJ68782.1 - 3.3 7.7 9.5 1.5 8.8 7.5 1.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LigT_PEase PF02834.16 CDJ68783.1 - 0.048 13.8 0.2 0.17 12.1 0.2 2.0 1 0 0 1 1 1 0 LigT like Phosphoesterase RIFIN PF02009.16 CDJ68785.1 - 4.7 7.0 20.0 7 6.4 20.0 1.3 1 0 0 1 1 1 0 Rifin Cpn60_TCP1 PF00118.24 CDJ68786.1 - 6.1e-135 450.6 5.9 7e-135 450.4 5.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AIRC PF00731.20 CDJ68786.1 - 0.17 11.4 2.0 0.35 10.4 0.0 2.5 3 0 0 3 3 3 0 AIR carboxylase TPR_2 PF07719.17 CDJ68787.1 - 3e-13 48.8 20.6 0.0051 16.8 0.7 6.9 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ68787.1 - 1.5e-09 38.3 16.7 0.0035 17.8 10.3 4.9 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ68787.1 - 3.2e-08 33.7 30.7 0.00015 22.3 2.0 6.7 3 1 4 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ68787.1 - 3.6e-08 32.9 12.0 0.01 15.6 0.3 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ68787.1 - 3.4e-07 30.4 20.9 0.02 15.1 0.1 5.3 2 2 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ68787.1 - 1.6e-06 27.9 12.2 0.013 15.7 0.6 6.1 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ68787.1 - 2.1e-06 28.0 16.7 0.028 15.0 1.3 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ68787.1 - 2.1e-05 24.7 7.6 0.066 13.4 1.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CDJ68787.1 - 3e-05 24.1 1.4 0.012 16.0 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ68787.1 - 3.2e-05 24.5 18.0 0.00011 22.8 9.0 6.3 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ68787.1 - 6.7e-05 22.6 9.2 0.93 9.7 0.2 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CDJ68787.1 - 0.0055 16.3 2.5 0.25 11.0 0.6 3.0 3 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_11 PF13414.6 CDJ68787.1 - 0.007 16.0 9.3 1 9.1 0.1 5.4 5 1 1 6 6 6 1 TPR repeat TPR_3 PF07720.12 CDJ68787.1 - 0.0071 16.3 1.0 0.54 10.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ68787.1 - 0.0088 16.2 3.3 0.0088 16.2 3.3 4.8 6 2 1 7 7 7 1 Tetratricopeptide repeat DUF3808 PF10300.9 CDJ68787.1 - 0.013 14.3 0.2 0.043 12.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) RPN7 PF10602.9 CDJ68787.1 - 0.023 14.4 0.5 1.5 8.5 0.0 3.0 4 0 0 4 4 4 0 26S proteasome subunit RPN7 TAF1_subA PF14929.6 CDJ68787.1 - 0.048 13.1 0.1 0.68 9.3 0.0 2.1 2 0 0 2 2 2 0 TAF RNA Polymerase I subunit A TPR_10 PF13374.6 CDJ68787.1 - 0.056 13.3 7.6 23 5.0 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat CCSAP PF15748.5 CDJ68788.1 - 0.0093 16.2 36.8 0.011 15.9 36.8 1.0 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ68788.1 - 0.31 10.8 24.8 0.37 10.6 24.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.8 CDJ68788.1 - 1.4 7.9 41.7 1.7 7.7 41.7 1.1 1 0 0 1 1 1 0 SprA-related family BAF1_ABF1 PF04684.13 CDJ68788.1 - 1.7 7.6 23.2 2 7.4 23.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ68788.1 - 2.4 8.1 45.0 3 7.7 45.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF966 PF06136.13 CDJ68788.1 - 2.7 7.6 27.7 3.3 7.3 27.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4746 PF15928.5 CDJ68788.1 - 4.5 6.6 13.7 5.7 6.3 13.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Neur_chan_memb PF02932.16 CDJ68788.1 - 4.7 7.2 21.0 7.8 6.5 21.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.11 CDJ68788.1 - 7 6.6 19.3 8.6 6.3 19.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDK5_activator PF03261.15 CDJ68788.1 - 9.8 5.6 21.3 12 5.4 21.3 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PCM1_C PF15717.5 CDJ68789.1 - 3 6.4 6.2 0.59 8.8 0.3 2.0 2 0 0 2 2 2 0 Pericentriolar material 1 C terminus Secretin_N_2 PF07655.13 CDJ68790.1 - 0.12 12.9 11.6 0.15 12.6 11.6 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Macoilin PF09726.9 CDJ68790.1 - 0.29 9.7 3.2 0.28 9.7 3.2 1.0 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 CDJ68790.1 - 0.37 10.4 21.6 0.46 10.1 21.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ68790.1 - 0.59 8.9 4.2 0.56 9.0 4.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 CDJ68790.1 - 6.2 6.8 9.4 7.8 6.4 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) ENTH PF01417.20 CDJ68792.1 - 6.2e-28 97.4 0.0 1.1e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 ENTH domain RskA PF10099.9 CDJ68793.1 - 0.0082 16.5 8.1 0.014 15.7 8.1 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF4760 PF15956.5 CDJ68793.1 - 0.057 13.6 1.9 0.97 9.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4760) M_domain PF12938.7 CDJ68793.1 - 0.11 12.3 31.6 0.36 10.6 12.1 2.3 2 0 0 2 2 2 0 M domain of GW182 ANAPC_CDC26 PF10471.9 CDJ68793.1 - 1 10.2 26.5 1.2 10.0 10.2 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 SUIM_assoc PF16619.5 CDJ68793.1 - 1.2 9.3 39.5 2.6 8.2 11.3 2.5 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Activator_LAG-3 PF11498.8 CDJ68793.1 - 4 6.3 34.9 0.87 8.5 9.6 2.0 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Presenilin PF01080.17 CDJ68793.1 - 4.4 6.0 6.2 5.6 5.6 6.2 1.1 1 0 0 1 1 1 0 Presenilin Seryl_tRNA_N PF02403.22 CDJ68794.1 - 0.23 11.7 8.7 0.78 10.0 1.2 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spt20 PF12090.8 CDJ68795.1 - 0.00026 20.7 30.4 0.00027 20.6 30.4 1.2 1 0 0 1 1 1 1 Spt20 family RskA PF10099.9 CDJ68795.1 - 0.00091 19.6 18.8 0.0012 19.2 18.8 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF1754 PF08555.10 CDJ68795.1 - 0.0075 17.0 10.4 0.01 16.6 10.4 1.2 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) NARP1 PF12569.8 CDJ68795.1 - 0.081 11.8 13.8 0.092 11.6 13.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SpoIIP PF07454.11 CDJ68795.1 - 0.083 12.3 11.2 0.086 12.3 11.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 CDJ68795.1 - 0.1 12.5 40.2 0.12 12.4 40.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1980 PF09323.10 CDJ68795.1 - 0.13 12.2 10.4 0.16 11.9 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Connexin PF00029.19 CDJ68795.1 - 0.13 12.0 6.7 0.14 11.9 6.7 1.1 1 0 0 1 1 1 0 Connexin Activator_LAG-3 PF11498.8 CDJ68795.1 - 0.15 11.0 37.9 0.16 10.9 37.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 eIF-3_zeta PF05091.12 CDJ68795.1 - 0.24 10.3 16.9 0.24 10.3 16.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) XRCC4 PF06632.12 CDJ68795.1 - 0.25 10.2 12.7 0.29 9.9 12.7 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 TFB6 PF17110.5 CDJ68795.1 - 0.28 10.9 5.0 0.34 10.6 5.0 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 CDJ68795.1 - 0.3 10.8 5.7 0.44 10.2 5.7 1.3 1 0 0 1 1 1 0 FAM176 family Paf1 PF03985.13 CDJ68795.1 - 0.32 10.0 12.6 0.32 10.0 12.6 1.1 1 0 0 1 1 1 0 Paf1 Med15 PF09606.10 CDJ68795.1 - 0.35 9.5 32.0 0.43 9.2 32.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal V_ATPase_I PF01496.19 CDJ68795.1 - 0.37 8.6 11.5 0.37 8.7 11.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Suf PF05843.14 CDJ68795.1 - 0.38 10.7 20.9 0.39 10.6 20.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Macoilin PF09726.9 CDJ68795.1 - 0.39 9.2 12.7 0.5 8.9 12.7 1.2 1 0 0 1 1 1 0 Macoilin family MecA PF05389.12 CDJ68795.1 - 0.43 10.2 9.1 0.47 10.1 9.1 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Band_3_cyto PF07565.13 CDJ68795.1 - 0.48 10.2 11.1 0.52 10.1 11.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MMR1 PF08505.10 CDJ68795.1 - 0.53 10.5 20.5 0.63 10.3 20.5 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CLN3 PF02487.17 CDJ68795.1 - 0.56 9.2 6.8 0.56 9.2 6.8 1.2 1 0 0 1 1 1 0 CLN3 protein SID-1_RNA_chan PF13965.6 CDJ68795.1 - 0.56 8.5 3.4 0.56 8.6 3.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 CDJ68795.1 - 0.61 9.0 12.3 0.64 9.0 12.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Glt_symporter PF03616.14 CDJ68795.1 - 0.62 8.7 3.2 0.63 8.7 3.2 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF2126 PF09899.9 CDJ68795.1 - 0.64 8.0 8.0 0.65 8.0 8.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) TCP PF03634.13 CDJ68795.1 - 0.71 10.4 18.2 0.92 10.1 18.2 1.1 1 0 0 1 1 1 0 TCP family transcription factor DDHD PF02862.17 CDJ68795.1 - 0.83 9.8 15.3 1 9.5 15.3 1.1 1 0 0 1 1 1 0 DDHD domain NEMP PF10225.9 CDJ68795.1 - 0.85 9.2 3.8 0.89 9.2 3.8 1.1 1 0 0 1 1 1 0 NEMP family EOS1 PF12326.8 CDJ68795.1 - 0.9 9.4 5.9 1 9.3 5.9 1.2 1 0 0 1 1 1 0 N-glycosylation protein Endostatin PF06482.11 CDJ68795.1 - 1.1 8.7 13.5 1.1 8.6 13.5 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin BAF1_ABF1 PF04684.13 CDJ68795.1 - 1.1 8.2 14.4 1.5 7.7 14.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CSG2 PF16965.5 CDJ68795.1 - 1.2 8.0 5.1 1.2 8.0 5.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Sec62 PF03839.16 CDJ68795.1 - 1.3 8.5 8.2 1.4 8.4 8.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Neur_chan_memb PF02932.16 CDJ68795.1 - 1.3 9.0 10.8 1.3 9.0 10.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Velvet PF11754.8 CDJ68795.1 - 1.4 8.8 15.1 1.6 8.6 15.1 1.1 1 0 0 1 1 1 0 Velvet factor SMYLE_N PF18615.1 CDJ68795.1 - 1.4 8.4 13.8 1.7 8.2 13.8 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Pannexin_like PF12534.8 CDJ68795.1 - 1.5 7.9 8.0 1.5 7.8 8.0 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF572 PF04502.13 CDJ68795.1 - 1.5 8.4 18.2 1.8 8.1 18.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) SART-1 PF03343.13 CDJ68795.1 - 1.5 7.3 19.3 1.6 7.2 19.3 1.0 1 0 0 1 1 1 0 SART-1 family Folate_carrier PF01770.18 CDJ68795.1 - 1.5 7.4 8.6 2.1 7.0 8.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier ALMT PF11744.8 CDJ68795.1 - 1.6 7.5 10.0 1.6 7.5 10.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hydin_ADK PF17213.3 CDJ68795.1 - 1.6 9.0 20.0 2 8.7 20.0 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Peptidase_S49_N PF08496.10 CDJ68795.1 - 1.6 8.8 13.6 2 8.4 13.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF913 PF06025.12 CDJ68795.1 - 1.7 7.5 9.0 1.8 7.4 9.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CDJ68795.1 - 2.2 7.0 20.6 2.4 6.8 20.6 1.0 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.6 CDJ68795.1 - 2.3 8.1 20.0 2.8 7.8 20.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Baculo_PP31 PF05311.11 CDJ68795.1 - 2.5 7.5 11.8 2.6 7.5 11.8 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) MAJIN PF15077.6 CDJ68795.1 - 2.5 7.8 11.9 2.9 7.6 11.9 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein SprA-related PF12118.8 CDJ68795.1 - 2.7 7.1 36.9 3.5 6.7 36.9 1.0 1 0 0 1 1 1 0 SprA-related family PAT1 PF09770.9 CDJ68795.1 - 3.1 6.0 26.9 3.3 5.9 26.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PIP5K PF01504.18 CDJ68795.1 - 3.2 6.9 10.8 3.9 6.6 10.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Membralin PF09746.9 CDJ68795.1 - 3.4 6.6 6.3 3.5 6.6 6.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Peptidase_S15 PF02129.18 CDJ68795.1 - 3.7 7.1 13.4 4.7 6.7 13.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) UPF0560 PF10577.9 CDJ68795.1 - 4 5.8 20.8 4.3 5.7 20.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4770 PF15994.5 CDJ68795.1 - 4.3 7.5 14.7 5.8 7.1 14.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FAM60A PF15396.6 CDJ68795.1 - 4.8 7.1 12.1 5.4 7.0 12.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ68795.1 - 4.9 6.9 16.1 5.7 6.7 16.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MCU PF04678.13 CDJ68795.1 - 5.1 7.2 11.4 6.3 6.9 11.4 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Serinc PF03348.15 CDJ68795.1 - 5.9 5.7 9.5 6.4 5.6 9.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CCSAP PF15748.5 CDJ68795.1 - 6 7.0 19.5 7.5 6.6 19.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Plasmodium_Vir PF05795.11 CDJ68795.1 - 7.6 5.8 8.9 7.2 5.9 8.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein XRN_M PF17846.1 CDJ68795.1 - 7.6 5.4 10.3 8.4 5.2 10.3 1.2 1 0 0 1 1 1 0 Xrn1 helical domain PA26 PF04636.13 CDJ68795.1 - 8.7 5.1 12.2 9.7 5.0 12.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Het-C PF07217.11 CDJ68795.1 - 8.8 4.7 11.7 9.6 4.6 11.7 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C THOC2_N PF16134.5 CDJ68795.1 - 9.3 4.7 14.2 10 4.6 14.2 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus V_ATPase_I PF01496.19 CDJ68796.1 - 4.2e-153 511.2 0.1 4.8e-153 511.0 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ68796.1 - 0.0025 17.9 13.9 0.0031 17.6 13.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 CDJ68796.1 - 0.013 15.1 1.3 0.021 14.5 1.3 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SUIM_assoc PF16619.5 CDJ68796.1 - 0.019 15.0 1.9 0.019 15.0 1.9 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Suf PF05843.14 CDJ68796.1 - 0.12 12.3 3.0 0.2 11.6 3.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Dehydrin PF00257.19 CDJ68796.1 - 0.19 12.2 2.5 0.3 11.6 2.5 1.2 1 0 0 1 1 1 0 Dehydrin BatD PF13584.6 CDJ68796.1 - 0.3 9.9 7.1 0.14 11.0 0.4 2.2 1 1 0 2 2 2 0 Oxygen tolerance RR_TM4-6 PF06459.12 CDJ68796.1 - 5 6.9 5.9 8.3 6.2 5.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BAF1_ABF1 PF04684.13 CDJ68796.1 - 5.7 5.9 6.3 8.1 5.4 6.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4969 PF16339.5 CDJ68797.1 - 3.8 7.9 0.0 3.8 7.9 0.0 3.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4969) V_ATPase_I PF01496.19 CDJ68798.1 - 4.9e-51 173.6 0.0 6.3e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family QCR10 PF09796.9 CDJ68798.1 - 0.66 10.1 0.0 0.66 10.1 0.0 2.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Ribosomal_60s PF00428.19 CDJ68798.1 - 1.6 9.4 21.0 0.57 10.8 4.2 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein zf-C3HC4_3 PF13920.6 CDJ68799.1 - 0.00043 20.1 13.3 0.00096 19.0 13.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CDJ68799.1 - 0.0014 18.8 9.1 0.0028 17.7 9.1 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 CDJ68799.1 - 0.0014 18.4 15.9 0.0032 17.3 15.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SR-25 PF10500.9 CDJ68799.1 - 0.0017 18.0 8.5 0.0017 18.0 8.5 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein TAF4 PF05236.14 CDJ68799.1 - 0.0087 15.8 0.0 0.0087 15.8 0.0 2.7 2 2 0 2 2 1 1 Transcription initiation factor TFIID component TAF4 family zf-RING_2 PF13639.6 CDJ68799.1 - 0.012 15.9 16.6 0.03 14.6 16.6 1.7 1 0 0 1 1 1 0 Ring finger domain Ribosomal_60s PF00428.19 CDJ68799.1 - 0.013 16.1 10.6 0.013 16.1 10.6 6.4 3 2 2 5 5 3 0 60s Acidic ribosomal protein DWNN PF08783.11 CDJ68799.1 - 0.024 14.9 0.0 0.094 13.0 0.0 2.0 1 1 0 1 1 1 0 DWNN domain zf-RING_UBOX PF13445.6 CDJ68799.1 - 0.035 14.1 12.5 0.099 12.7 12.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ68799.1 - 0.045 13.7 18.6 0.17 11.9 18.6 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ68799.1 - 0.13 12.2 15.9 0.34 10.8 15.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ68799.1 - 1.7 8.9 15.0 6.9 6.9 15.0 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RskA PF10099.9 CDJ68800.1 - 0.0018 18.6 0.0 0.0018 18.6 0.0 4.6 3 2 1 4 4 4 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ68800.1 - 0.0036 17.0 15.9 0.0036 17.0 15.9 2.4 3 0 0 3 3 3 1 Spt20 family TPR_1 PF00515.28 CDJ68800.1 - 0.006 16.4 1.2 0.0081 15.9 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ68800.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat BRF1 PF07741.13 CDJ68800.1 - 0.74 10.2 11.5 1.5 9.2 3.4 3.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain GYF PF02213.16 CDJ68802.1 - 1.5e-05 24.6 0.1 2.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 GYF domain Apt1 PF10351.9 CDJ68802.1 - 1 8.2 6.2 1.8 7.3 6.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain AFG1_ATPase PF03969.16 CDJ68803.1 - 7.2e-72 242.3 0.0 1.5e-69 234.6 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.18 CDJ68803.1 - 0.00019 21.4 0.1 0.00037 20.4 0.1 1.5 1 1 0 1 1 1 1 Bacterial dnaA protein TniB PF05621.11 CDJ68803.1 - 0.012 15.0 0.0 0.086 12.2 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 CDJ68803.1 - 0.018 15.1 0.0 0.053 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ68803.1 - 0.04 13.8 0.0 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 CDJ68803.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDJ68803.1 - 0.12 12.7 0.2 6.3 7.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain Cullin PF00888.22 CDJ68804.1 - 1.8e-35 122.7 0.0 1.8e-30 106.1 0.0 2.4 3 0 0 3 3 3 2 Cullin family Cullin_Nedd8 PF10557.9 CDJ68804.1 - 2.9e-12 46.5 0.1 6.2e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain SR-25 PF10500.9 CDJ68804.1 - 0.093 12.3 11.9 0.16 11.6 11.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ68804.1 - 6.6 7.1 20.2 0.071 13.4 6.9 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain SprA-related PF12118.8 CDJ68805.1 - 0.0039 16.4 19.0 0.0039 16.4 19.0 2.4 2 1 1 3 3 3 1 SprA-related family DUF1645 PF07816.11 CDJ68805.1 - 0.025 15.2 0.4 0.025 15.2 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) Ndc1_Nup PF09531.10 CDJ68805.1 - 0.97 8.0 10.8 1.1 7.8 10.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MID_MedPIWI PF18296.1 CDJ68805.1 - 1 9.1 10.9 0.057 13.2 3.9 2.1 2 0 0 2 2 2 0 MID domain of medPIWI AF-4 PF05110.13 CDJ68805.1 - 2.2 6.2 38.6 0.029 12.5 23.7 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein NAM-associated PF14303.6 CDJ68805.1 - 2.5 8.8 18.6 0.13 12.9 10.5 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Peroxin-3 PF04882.12 CDJ68805.1 - 5.7 5.8 12.8 6.8 5.6 0.4 2.2 2 0 0 2 2 2 0 Peroxin-3 Utp14 PF04615.13 CDJ68806.1 - 0.36 9.4 27.5 0.4 9.2 27.5 1.0 1 0 0 1 1 1 0 Utp14 protein SLC12 PF03522.15 CDJ68806.1 - 0.44 9.5 18.6 0.61 9.0 18.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 MAP65_ASE1 PF03999.12 CDJ68806.1 - 0.5 9.0 22.0 0.7 8.5 22.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF572 PF04502.13 CDJ68806.1 - 1.4 8.5 24.2 1.9 8.0 24.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SPX PF03105.19 CDJ68806.1 - 2.1 8.2 23.0 2.9 7.7 23.0 1.3 1 0 0 1 1 1 0 SPX domain AP3D1 PF06375.11 CDJ68806.1 - 3.6 7.8 17.5 1.2 9.4 6.8 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Spt20 PF12090.8 CDJ68806.1 - 5.3 6.6 57.1 1 8.9 26.7 2.5 3 0 0 3 3 3 0 Spt20 family GREB1 PF15782.5 CDJ68806.1 - 6.5 3.7 31.5 8.3 3.4 31.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAPS PF04499.15 CDJ68806.1 - 7.6 5.2 15.7 12 4.5 15.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SUIM_assoc PF16619.5 CDJ68807.1 - 4.1e-05 23.5 0.1 4.1e-05 23.5 0.1 12.8 9 4 1 10 10 10 2 Unstructured region C-term to UIM in Ataxin3 PHD PF00628.29 CDJ68807.1 - 7e-05 22.6 2.7 7e-05 22.6 2.7 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 CDJ68807.1 - 0.00084 18.8 4.6 0.00084 18.8 4.6 2.0 2 0 0 2 2 2 1 PHD-finger AP2 PF00847.20 CDJ68807.1 - 4.7 7.5 8.0 0.74 10.1 0.1 3.2 2 0 0 2 2 2 0 AP2 domain SR-25 PF10500.9 CDJ68808.1 - 3.2e-07 30.2 13.2 4.3e-07 29.8 13.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RSRP PF17069.5 CDJ68808.1 - 0.06 12.9 16.1 0.079 12.5 16.1 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 TCP PF03634.13 CDJ68808.1 - 0.15 12.6 13.5 0.21 12.2 13.5 1.1 1 0 0 1 1 1 0 TCP family transcription factor Suf PF05843.14 CDJ68808.1 - 0.19 11.7 19.1 0.27 11.2 19.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LEA_3 PF03242.13 CDJ68808.1 - 0.34 11.7 8.7 0.071 13.8 3.9 1.9 1 1 1 2 2 2 0 Late embryogenesis abundant protein RR_TM4-6 PF06459.12 CDJ68808.1 - 0.37 10.6 6.5 0.54 10.0 6.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AUX_IAA PF02309.16 CDJ68808.1 - 0.69 9.7 12.1 0.88 9.4 12.1 1.0 1 0 0 1 1 1 0 AUX/IAA family SprA-related PF12118.8 CDJ68808.1 - 0.99 8.5 25.7 1.2 8.2 25.7 1.1 1 0 0 1 1 1 0 SprA-related family MAP70 PF07058.11 CDJ68808.1 - 1 8.0 7.4 1.1 7.9 7.4 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 eIF-3_zeta PF05091.12 CDJ68808.1 - 1.5 7.7 13.2 2 7.3 13.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ68808.1 - 2.9 7.8 36.2 3.9 7.4 36.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM199X PF15814.5 CDJ68808.1 - 3.1 6.8 15.7 3.7 6.5 15.7 1.1 1 0 0 1 1 1 0 Protein family FAM199X DUF3043 PF11241.8 CDJ68808.1 - 3.1 7.8 9.6 1.9 8.5 7.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) PIP5K PF01504.18 CDJ68808.1 - 3.8 6.7 10.8 5.3 6.2 10.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SRP-alpha_N PF04086.13 CDJ68808.1 - 3.9 7.3 13.8 4.6 7.1 13.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Velvet PF11754.8 CDJ68808.1 - 4 7.3 18.2 5 7.0 18.2 1.1 1 0 0 1 1 1 0 Velvet factor Presenilin PF01080.17 CDJ68808.1 - 4.7 5.9 19.7 5.8 5.6 19.7 1.0 1 0 0 1 1 1 0 Presenilin XRCC4 PF06632.12 CDJ68808.1 - 4.9 5.9 11.0 6.8 5.4 11.0 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 GREB1 PF15782.5 CDJ68808.1 - 7.2 3.6 17.1 8.3 3.4 17.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RICTOR_N PF14664.6 CDJ68808.1 - 7.7 5.4 7.9 2.1 7.2 5.3 1.4 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Neur_chan_memb PF02932.16 CDJ68808.1 - 8.6 6.3 10.7 13 5.7 10.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Trypan_PARP PF05887.11 CDJ68809.1 - 0.16 11.9 6.0 0.2 11.6 6.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Collagen PF01391.18 CDJ68810.1 - 5.5e-05 22.8 30.3 5.5e-05 22.8 30.3 5.1 5 0 0 5 5 5 1 Collagen triple helix repeat (20 copies) Herpes_DNAp_acc PF04929.12 CDJ68811.1 - 0.048 12.6 7.1 0.15 11.1 7.1 1.9 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2721 PF11026.8 CDJ68812.1 - 0.0027 17.6 5.3 0.0035 17.2 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Spt20 PF12090.8 CDJ68812.1 - 0.0029 17.2 13.4 0.0032 17.1 13.4 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ68812.1 - 0.0054 15.7 8.0 0.0061 15.6 8.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF3464 PF11947.8 CDJ68812.1 - 0.13 12.0 5.3 0.18 11.5 5.2 1.3 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 TFIIA PF03153.13 CDJ68812.1 - 0.17 11.8 20.5 0.24 11.4 20.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RITA PF17066.5 CDJ68812.1 - 0.6 9.6 12.1 0.69 9.5 12.1 1.0 1 0 0 1 1 1 0 RBPJ-interacting and tubulin associated protein Tic110 PF16940.5 CDJ68812.1 - 0.69 8.3 25.1 0.85 8.0 25.1 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF4813 PF16072.5 CDJ68812.1 - 1.5 8.4 26.8 1.7 8.3 26.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) PCM1_C PF15717.5 CDJ68812.1 - 3 6.4 11.5 4 6.0 11.5 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus FSA_C PF10479.9 CDJ68812.1 - 3.5 5.7 10.2 3.5 5.7 10.2 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FRQ PF09421.10 CDJ68812.1 - 3.8 5.4 10.2 4.5 5.2 10.2 1.1 1 0 0 1 1 1 0 Frequency clock protein Tam41_Mmp37 PF09139.11 CDJ68812.1 - 8.3 5.7 9.5 9.5 5.5 9.5 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial BAF1_ABF1 PF04684.13 CDJ68813.1 - 1 8.4 41.1 0.27 10.3 11.3 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor NOGCT PF08155.11 CDJ68814.1 - 3.2e-24 84.7 2.8 3.2e-24 84.7 2.8 2.4 2 0 0 2 2 2 1 NOGCT (NUC087) domain GDA1_CD39 PF01150.17 CDJ68815.1 - 1.7e-27 96.1 3.3 9.5e-18 64.1 0.0 4.1 3 1 0 3 3 3 3 GDA1/CD39 (nucleoside phosphatase) family SR-25 PF10500.9 CDJ68815.1 - 0.0015 18.2 12.5 0.0015 18.2 12.5 5.4 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein Collagen PF01391.18 CDJ68815.1 - 0.022 14.5 29.4 0.072 12.9 29.4 1.9 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) U1snRNP70_N PF12220.8 CDJ68815.1 - 0.54 10.9 15.2 0.061 14.0 4.7 3.2 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal uDENN PF03456.18 CDJ68815.1 - 3.1 8.6 7.2 2.9 8.7 2.5 3.4 2 1 0 2 2 2 0 uDENN domain Ferlin_C PF16165.5 CDJ68816.1 - 3.6 7.5 5.7 6.5 6.7 5.7 1.5 1 0 0 1 1 1 0 Ferlin C-terminus CDC45 PF02724.14 CDJ68816.1 - 7.2 4.8 9.8 7.9 4.6 7.2 1.9 2 0 0 2 2 2 0 CDC45-like protein Ribosomal_60s PF00428.19 CDJ68819.1 - 0.011 16.3 10.6 0.021 15.4 10.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein CCDC53 PF10152.9 CDJ68819.1 - 0.2 12.1 2.1 0.26 11.7 2.1 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3138 PF11336.8 CDJ68819.1 - 0.51 8.9 3.0 0.53 8.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spt20 PF12090.8 CDJ68820.1 - 4.1 6.9 21.2 6 6.4 9.2 2.2 2 0 0 2 2 2 0 Spt20 family Peptidase_C48 PF02902.19 CDJ68822.1 - 4.5e-11 43.0 0.0 1.9e-10 40.9 0.0 2.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_M17 PF00883.21 CDJ68823.1 - 7.3e-116 386.8 0.1 1.1e-115 386.2 0.1 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CDJ68823.1 - 2.8e-12 46.6 2.6 4.4e-12 46.0 0.3 2.3 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain Bot1p PF12298.8 CDJ68825.1 - 0.088 13.0 1.4 2.8 8.1 0.8 2.5 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein DUF2935 PF11155.8 CDJ68825.1 - 0.57 10.5 4.2 0.94 9.8 1.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) SSP160 PF06933.11 CDJ68826.1 - 0.015 13.6 35.4 0.0084 14.4 13.0 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 tRNA_synthFbeta PF17759.1 CDJ68826.1 - 0.055 12.9 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain Mucin PF01456.17 CDJ68826.1 - 0.13 12.2 54.4 0.36 10.8 18.1 2.4 3 0 0 3 3 3 0 Mucin-like glycoprotein RabGAP-TBC PF00566.18 CDJ68827.1 - 1.8e-33 116.1 0.6 7.5e-18 65.0 0.1 3.1 2 1 0 2 2 2 2 Rab-GTPase-TBC domain SlyX PF04102.12 CDJ68827.1 - 0.00036 21.1 2.8 0.17 12.5 1.3 3.3 3 0 0 3 3 3 2 SlyX Peptidase_C48 PF02902.19 CDJ68828.1 - 0.00033 20.6 0.0 0.0034 17.3 0.0 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Herpes_gE PF02480.16 CDJ68828.1 - 0.048 12.4 0.0 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SR-25 PF10500.9 CDJ68833.1 - 0.004 16.8 6.7 0.004 16.8 6.7 3.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ68833.1 - 0.012 15.6 36.1 0.081 12.9 9.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Flavokinase PF01687.17 CDJ68836.1 - 5.7e-10 39.5 0.0 2.9e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Riboflavin kinase DUF4486 PF14858.6 CDJ68836.1 - 0.0057 15.2 0.7 0.0092 14.5 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) ANAPC_CDC26 PF10471.9 CDJ68836.1 - 0.0076 17.1 15.0 0.0076 17.1 15.0 6.6 5 2 0 5 5 5 2 Anaphase-promoting complex APC subunit CDC26 DDHD PF02862.17 CDJ68836.1 - 0.012 15.8 10.3 0.32 11.1 3.2 2.5 2 0 0 2 2 2 0 DDHD domain DUF4471 PF14740.6 CDJ68836.1 - 0.037 13.2 1.6 0.08 12.1 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) O-antigen_lig PF13425.6 CDJ68836.1 - 0.052 12.3 0.3 0.074 11.8 0.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein UPF0240 PF06784.11 CDJ68836.1 - 0.072 13.1 6.6 0.2 11.7 6.6 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) Pkinase PF00069.25 CDJ68837.1 - 6.4e-30 104.4 5.0 2.9e-14 53.1 0.0 3.7 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ68837.1 - 2.4e-09 36.9 0.8 8.6e-09 35.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase SUIM_assoc PF16619.5 CDJ68837.1 - 0.00047 20.2 0.1 0.00047 20.2 0.1 8.7 6 1 2 8 8 8 1 Unstructured region C-term to UIM in Ataxin3 Collagen PF01391.18 CDJ68837.1 - 0.0066 16.2 13.0 0.012 15.4 13.0 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Methyltransf_16 PF10294.9 CDJ68839.1 - 1.5e-05 24.8 0.1 0.034 13.9 0.3 3.3 2 1 0 2 2 2 2 Lysine methyltransferase Spt20 PF12090.8 CDJ68841.1 - 0.57 9.8 12.5 0.88 9.1 12.5 1.2 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 CDJ68841.1 - 3.5 6.5 10.3 4.9 6.0 10.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ68841.1 - 7.3 7.6 6.4 20 6.2 6.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF1645 PF07816.11 CDJ68842.1 - 0.004 17.8 2.6 0.004 17.8 2.6 5.1 3 2 1 4 4 4 1 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ68842.1 - 0.0044 16.7 10.0 0.0044 16.7 10.0 5.9 4 2 1 5 5 5 2 Nuclear RNA-splicing-associated protein DUF3740 PF12548.8 CDJ68842.1 - 0.071 13.6 15.8 9.9 6.6 0.0 3.5 3 0 0 3 3 3 0 Sulfatase protein Activator_LAG-3 PF11498.8 CDJ68842.1 - 0.31 9.9 42.1 1.5 7.7 7.3 2.7 2 0 0 2 2 2 0 Transcriptional activator LAG-3 MRNIP PF15749.5 CDJ68842.1 - 1.1 10.0 24.8 0.78 10.5 10.2 3.2 3 0 0 3 3 3 0 MRN-interacting protein DUF702 PF05142.12 CDJ68842.1 - 3.6 8.1 19.9 16 6.0 7.6 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF702) Utp14 PF04615.13 CDJ68842.1 - 4.4 5.8 31.7 9.5 4.7 31.0 1.7 1 1 1 2 2 2 0 Utp14 protein DUF4239 PF14023.6 CDJ68842.1 - 4.7 6.9 7.2 0.77 9.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) AP3D1 PF06375.11 CDJ68842.1 - 6.1 7.1 20.5 9.7 6.4 0.1 3.6 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 Eapp_C PF10238.9 CDJ68842.1 - 7.1 6.7 21.9 5.7 7.0 6.6 3.4 3 0 0 3 3 3 0 E2F-associated phosphoprotein AP2 PF00847.20 CDJ68844.1 - 1e-11 44.9 0.5 4.4e-11 42.8 0.5 2.1 1 0 0 1 1 1 1 AP2 domain MtN3_slv PF03083.16 CDJ68845.1 - 4.2e-34 116.4 3.6 4.6e-19 68.2 0.2 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange LAB_N PF07578.11 CDJ68845.1 - 0.0012 18.9 0.2 2 8.6 0.0 2.7 2 0 0 2 2 2 2 Lipid A Biosynthesis N-terminal domain SAE2 PF08573.10 CDJ68848.1 - 5.9e-08 33.8 0.8 5.9e-08 33.8 0.8 5.1 4 1 1 5 5 5 1 DNA repair protein endonuclease SAE2/CtIP C-terminus PAN_4 PF14295.6 CDJ68849.1 - 0.014 15.3 0.9 0.052 13.5 0.9 2.0 1 0 0 1 1 1 0 PAN domain PAN_1 PF00024.26 CDJ68849.1 - 0.016 15.1 2.4 0.016 15.1 2.4 2.1 2 0 0 2 2 2 0 PAN domain Pkinase PF00069.25 CDJ68851.1 - 9.8e-61 205.4 0.0 1.6e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ68851.1 - 1.3e-37 129.5 0.6 1.6e-37 129.2 0.0 1.4 2 0 0 2 2 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ68851.1 - 2.7e-15 56.5 0.0 8.1e-15 54.9 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ68851.1 - 4.5e-06 26.2 0.0 7.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ68851.1 - 1e-05 25.6 0.1 1e-05 25.6 0.1 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ68851.1 - 0.00062 18.6 0.5 0.012 14.4 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 CDJ68851.1 - 0.0056 15.7 0.0 0.0094 14.9 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CDJ68851.1 - 0.022 14.3 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase TFIIA PF03153.13 CDJ68851.1 - 0.045 13.7 21.7 0.058 13.4 21.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 CDJ68851.1 - 5 7.2 17.7 7.1 6.7 17.7 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Hamartin PF04388.12 CDJ68851.1 - 5.2 5.6 17.5 6.8 5.2 17.5 1.1 1 0 0 1 1 1 0 Hamartin protein RR_TM4-6 PF06459.12 CDJ68851.1 - 7.3 6.3 6.8 10 5.9 6.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 CDJ68851.1 - 8.6 6.3 16.8 14 5.5 16.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) KAR9 PF08580.10 CDJ68851.1 - 9 4.7 13.9 12 4.3 13.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 LMBR1 PF04791.16 CDJ68852.1 - 0.07 12.0 9.9 0.1 11.5 9.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.11 CDJ68852.1 - 0.098 11.1 25.4 0.16 10.4 25.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 CDJ68852.1 - 0.24 11.2 28.9 0.045 13.6 22.2 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Radical_SAM_N PF08497.10 CDJ68852.1 - 0.5 9.5 10.6 1.2 8.3 10.6 1.7 1 0 0 1 1 1 0 Radical SAM N-terminal SID-1_RNA_chan PF13965.6 CDJ68852.1 - 0.67 8.3 7.2 0.98 7.8 7.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FapA PF03961.13 CDJ68852.1 - 0.85 8.2 15.6 1.5 7.3 15.6 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A FHIPEP PF00771.20 CDJ68852.1 - 9.1 4.6 23.7 14 4.0 23.7 1.3 1 0 0 1 1 1 0 FHIPEP family BAF1_ABF1 PF04684.13 CDJ68852.1 - 9.5 5.1 29.3 0.67 8.9 19.7 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor ORC3_N PF07034.11 CDJ68853.1 - 2.2e-12 46.8 3.1 6.9e-12 45.1 0.0 3.3 3 1 0 3 3 3 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 CDJ68853.1 - 4.8e-05 23.4 0.0 4.8e-05 23.4 0.0 3.8 4 1 0 4 4 4 1 Origin recognition complex winged helix C-terminal EGF_CA PF07645.15 CDJ68854.1 - 3.1e-24 84.9 67.4 6.7e-11 42.2 9.1 4.7 5 0 0 5 5 5 4 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ68854.1 - 2.6e-11 43.5 60.2 8.4e-05 22.7 9.7 5.2 5 0 0 5 5 5 4 EGF domain cEGF PF12662.7 CDJ68854.1 - 3.1e-09 36.6 29.5 0.0077 16.1 0.2 5.7 5 1 0 5 5 5 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDJ68854.1 - 2e-05 24.7 55.6 0.0071 16.6 2.1 4.9 4 1 0 5 5 5 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 CDJ68854.1 - 0.00044 20.5 47.7 0.013 15.7 5.7 5.2 5 0 0 5 5 5 4 EGF-like domain EGF_MSP1_1 PF12946.7 CDJ68854.1 - 0.00046 20.2 23.7 0.001 19.0 8.6 4.3 4 0 0 4 4 4 2 MSP1 EGF domain 1 hEGF PF12661.7 CDJ68854.1 - 0.0044 17.6 2.2 0.0044 17.6 2.2 6.0 5 0 0 5 5 5 2 Human growth factor-like EGF DUF348 PF03990.14 CDJ68854.1 - 0.034 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain 14-3-3 PF00244.20 CDJ68855.1 - 1.5e-98 328.8 7.3 1.7e-98 328.6 7.3 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.6 CDJ68855.1 - 0.033 13.6 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MKT1_N PF12247.8 CDJ68855.1 - 0.18 12.1 1.4 0.38 11.1 0.1 2.2 2 1 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication RT_RNaseH PF17917.1 CDJ68856.1 - 7.2e-18 64.8 0.1 1.2e-17 64.0 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ68856.1 - 1.1e-08 35.0 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1754 PF08555.10 CDJ68857.1 - 7.2e-07 29.9 9.6 0.0003 21.5 9.6 2.4 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Sld5 PF05916.11 CDJ68857.1 - 0.031 14.7 0.1 0.062 13.8 0.1 1.5 1 0 0 1 1 1 0 GINS complex protein HTH_32 PF13565.6 CDJ68857.1 - 0.033 14.8 1.7 0.033 14.8 1.7 2.9 3 0 0 3 3 3 0 Homeodomain-like domain IMD PF08397.11 CDJ68858.1 - 0.021 14.2 12.2 0.25 10.7 8.1 2.2 2 0 0 2 2 2 0 IRSp53/MIM homology domain MPS2 PF17060.5 CDJ68858.1 - 0.73 9.0 8.4 0.31 10.3 5.8 1.6 1 1 0 1 1 1 0 Monopolar spindle protein 2 Dishevelled PF02377.15 CDJ68859.1 - 0.013 16.0 11.9 0.019 15.4 11.9 1.3 1 0 0 1 1 1 0 Dishevelled specific domain CDC45 PF02724.14 CDJ68859.1 - 0.089 11.1 4.2 0.099 10.9 4.2 1.0 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 CDJ68859.1 - 0.56 10.1 14.1 0.67 9.8 14.1 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.12 CDJ68859.1 - 1.4 8.7 6.7 1.6 8.5 6.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 CDJ68859.1 - 1.4 6.9 6.7 1.6 6.8 6.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCDC106 PF15794.5 CDJ68859.1 - 2.1 8.0 14.5 2.6 7.7 14.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4551 PF15087.6 CDJ68859.1 - 2.6 6.8 8.6 2.9 6.6 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FAM199X PF15814.5 CDJ68859.1 - 2.9 6.9 17.0 3.4 6.6 17.0 1.0 1 0 0 1 1 1 0 Protein family FAM199X Bax1-I PF01027.20 CDJ68860.1 - 3.3e-30 105.5 24.2 3.9e-30 105.2 24.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PGG PF13962.6 CDJ68860.1 - 0.41 10.5 12.1 0.45 10.4 1.9 2.8 3 0 0 3 3 3 0 Domain of unknown function CPP1-like PF11833.8 CDJ68860.1 - 4.7 6.8 10.3 0.59 9.8 5.4 1.9 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PIG-Y PF15159.6 CDJ68861.1 - 5.1e-09 36.9 4.3 5.1e-09 36.9 4.3 1.9 2 0 0 2 2 2 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF2722 PF10846.8 CDJ68861.1 - 0.013 14.5 9.9 0.016 14.1 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2721 PF11026.8 CDJ68861.1 - 0.016 15.1 2.4 0.016 15.1 2.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) TFIIA PF03153.13 CDJ68861.1 - 0.016 15.2 15.6 0.023 14.7 15.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ68861.1 - 0.039 12.0 4.0 0.058 11.5 4.0 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Spt20 PF12090.8 CDJ68861.1 - 0.078 12.6 14.2 0.1 12.2 14.2 1.2 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.10 CDJ68861.1 - 0.2 10.3 15.8 0.24 10.0 15.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MccV PF17508.2 CDJ68861.1 - 0.37 11.4 11.6 0.59 10.7 11.6 1.3 1 0 0 1 1 1 0 Microcin V bacteriocin GREB1 PF15782.5 CDJ68861.1 - 0.74 6.9 4.0 0.84 6.7 4.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer UBD PF16455.5 CDJ68861.1 - 1.6 9.1 8.9 2.6 8.3 8.9 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain AP3D1 PF06375.11 CDJ68862.1 - 0.0057 16.9 9.0 0.0057 16.9 9.0 2.9 2 1 0 2 2 2 1 AP-3 complex subunit delta-1 TFIIF_alpha PF05793.12 CDJ68862.1 - 7 5.1 38.2 0.072 11.7 5.3 2.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Myc_N PF01056.18 CDJ68863.1 - 0.023 14.6 12.0 0.046 13.6 12.0 1.4 1 0 0 1 1 1 0 Myc amino-terminal region TFIIA PF03153.13 CDJ68863.1 - 0.026 14.6 24.6 0.37 10.7 15.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ68863.1 - 0.054 12.2 9.9 0.025 13.3 6.7 1.9 2 0 0 2 2 2 0 Presenilin CCDC53 PF10152.9 CDJ68863.1 - 0.24 11.8 15.6 4.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Spore_coat_CotO PF14153.6 CDJ68863.1 - 0.48 10.3 28.1 2.8 7.8 24.9 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Med15 PF09606.10 CDJ68863.1 - 0.51 9.0 21.2 1.2 7.8 2.8 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal NOA36 PF06524.12 CDJ68863.1 - 0.63 9.3 13.5 0.9 8.8 13.5 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 CDJ68863.1 - 2.4 7.7 15.4 3.9 7.0 15.4 1.3 1 0 0 1 1 1 0 PPP4R2 Ribosomal_L27A PF00828.19 CDJ68864.1 - 4.6e-23 82.3 0.0 5.9e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A zf-CpG_bind_C PF12269.8 CDJ68867.1 - 0.41 10.4 5.5 0.1 12.4 1.3 1.9 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain AT_hook PF02178.19 CDJ68868.1 - 6.2 7.0 13.0 0.3 11.1 5.3 3.1 2 0 0 2 2 2 0 AT hook motif Presenilin PF01080.17 CDJ68869.1 - 0.0087 14.9 2.3 0.0096 14.7 2.3 1.2 1 0 0 1 1 1 1 Presenilin Apt1 PF10351.9 CDJ68869.1 - 0.051 12.4 2.2 0.055 12.3 2.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4131 PF13567.6 CDJ68869.1 - 0.35 10.5 5.6 0.12 12.0 2.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4407 PF14362.6 CDJ68869.1 - 0.68 9.2 14.0 0.95 8.8 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) His_Phos_2 PF00328.22 CDJ68869.1 - 2.6 7.3 12.5 1.3e+02 1.7 12.5 2.1 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) FxsA PF04186.13 CDJ68869.1 - 8.1 6.6 14.0 0.71 10.0 0.8 3.3 1 1 3 4 4 4 0 FxsA cytoplasmic membrane protein GDP_Man_Dehyd PF16363.5 CDJ68870.1 - 0.85 9.0 3.7 1.2 8.5 3.7 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MMR1 PF08505.10 CDJ68870.1 - 1.1 9.6 4.8 1.3 9.2 4.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein IER PF05760.12 CDJ68870.1 - 1.1 9.5 11.8 1.3 9.2 11.8 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF4670 PF15709.5 CDJ68870.1 - 1.2 8.3 25.8 1.7 7.9 25.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) eIF3_subunit PF08597.10 CDJ68870.1 - 1.6 8.6 15.1 1.9 8.4 15.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Casc1_N PF15927.5 CDJ68870.1 - 5.1 6.7 22.4 0.53 9.9 17.5 1.7 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus RskA PF10099.9 CDJ68870.1 - 9.7 6.4 17.8 0.093 13.0 7.7 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA AF-4 PF05110.13 CDJ68872.1 - 0.2 9.7 61.5 0.22 9.6 61.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RskA PF10099.9 CDJ68875.1 - 0.0011 19.3 6.7 0.0011 19.3 6.7 3.7 2 1 1 3 3 3 1 Anti-sigma-K factor rskA AAA_23 PF13476.6 CDJ68875.1 - 0.013 16.0 3.8 0.013 16.0 3.8 2.3 2 0 0 2 2 1 0 AAA domain SOBP PF15279.6 CDJ68875.1 - 0.13 12.8 26.4 0.19 12.3 26.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SWIM PF04434.17 CDJ68875.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.8 2 0 0 2 2 2 0 SWIM zinc finger Hamartin PF04388.12 CDJ68875.1 - 0.26 9.9 23.3 0.33 9.6 23.3 1.1 1 0 0 1 1 1 0 Hamartin protein LAP1C PF05609.12 CDJ68875.1 - 0.38 9.8 26.1 0.49 9.4 26.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GET2 PF08690.10 CDJ68875.1 - 2.2 7.9 27.3 3.2 7.4 27.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 PAT1 PF09770.9 CDJ68875.1 - 2.4 6.3 29.2 3.1 6.0 29.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAP1 PF07218.11 CDJ68875.1 - 2.5 6.3 20.5 3.4 5.8 20.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) O-antigen_lig PF13425.6 CDJ68875.1 - 7.6 5.2 6.3 12 4.5 6.3 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3109 PF11307.8 CDJ68875.1 - 8.6 6.1 9.7 0.3 10.9 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3109) LMBR1 PF04791.16 CDJ68875.1 - 9.3 5.0 8.1 14 4.5 8.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein RskA PF10099.9 CDJ68876.1 - 0.0012 19.2 22.6 0.0012 19.2 22.6 3.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA VIR_N PF15912.5 CDJ68877.1 - 0.0041 16.8 20.2 0.0051 16.4 20.2 1.3 1 0 0 1 1 1 1 Virilizer, N-terminal RIFIN PF02009.16 CDJ68877.1 - 0.11 12.4 25.8 0.15 11.9 25.8 1.3 1 0 0 1 1 1 0 Rifin CDK5_activator PF03261.15 CDJ68877.1 - 5.3 6.5 34.9 6.3 6.2 34.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SAPS PF04499.15 CDJ68877.1 - 5.4 5.7 34.4 7.2 5.3 34.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RskA PF10099.9 CDJ68878.1 - 0.011 16.1 15.6 0.017 15.4 10.3 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA QH-AmDH_gamma PF08992.11 CDJ68878.1 - 0.11 12.5 3.4 0.13 12.2 1.7 1.9 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, gamma subunit Utp14 PF04615.13 CDJ68879.1 - 0.0005 18.8 6.4 0.0005 18.8 6.4 3.1 2 2 0 2 2 2 1 Utp14 protein GTP_EFTU PF00009.27 CDJ68880.1 - 1.1e-43 149.0 0.0 2e-25 89.5 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CDJ68880.1 - 6.1e-05 23.0 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II Phage_int_SAM_6 PF18644.1 CDJ68880.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain EFG_IV PF03764.18 CDJ68880.1 - 0.055 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Elongation factor G, domain IV EFG_C PF00679.24 CDJ68880.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G C-terminus YIF1 PF03878.15 CDJ68881.1 - 8.3e-37 127.0 1.7 2.9e-34 118.7 0.2 2.1 2 0 0 2 2 2 2 YIF1 PCI PF01399.27 CDJ68882.1 - 2e-14 54.0 0.1 3.4e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 PCI domain LCCL PF03815.19 CDJ68883.1 - 7.9e-21 74.0 0.1 2.3e-20 72.5 0.1 1.8 1 0 0 1 1 1 1 LCCL domain Rxt3 PF08642.10 CDJ68883.1 - 0.00026 21.8 0.1 0.2 12.4 0.0 2.7 2 0 0 2 2 2 2 Histone deacetylation protein Rxt3 COLFI PF01410.18 CDJ68883.1 - 0.0057 16.0 0.0 0.0057 16.0 0.0 1.8 2 0 0 2 2 2 1 Fibrillar collagen C-terminal domain Spt20 PF12090.8 CDJ68883.1 - 5.6 6.5 14.1 4.8 6.7 0.7 2.6 2 0 0 2 2 2 0 Spt20 family tRNA-synt_His PF13393.6 CDJ68884.1 - 0.051 12.8 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF3626 PF12294.8 CDJ68885.1 - 0.0026 16.8 0.0 0.0032 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3626) TPR_2 PF07719.17 CDJ68886.1 - 0.001 19.0 2.2 2 8.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_5 PF12688.7 CDJ68886.1 - 0.019 15.2 0.7 0.019 15.2 0.7 2.5 3 0 0 3 3 3 0 Tetratrico peptide repeat SET PF00856.28 CDJ68886.1 - 0.03 14.7 0.1 0.13 12.6 0.1 2.3 1 0 0 1 1 1 0 SET domain Prefoldin PF02996.17 CDJ68887.1 - 1.5e-20 73.3 0.6 2.1e-20 72.8 0.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF4530 PF15039.6 CDJ68887.1 - 0.036 14.2 0.1 0.07 13.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) RecG_N PF17190.4 CDJ68887.1 - 0.042 14.6 0.4 0.52 11.1 0.0 2.1 2 0 0 2 2 2 0 RecG N-terminal helical domain PDEase_I PF00233.19 CDJ68888.1 - 4.2e-20 72.5 0.5 3.2e-15 56.5 0.8 2.4 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CDJ68888.1 - 0.016 15.4 0.1 0.041 14.1 0.1 1.6 1 0 0 1 1 1 0 HD domain ASFV_J13L PF05568.11 CDJ68889.1 - 2.3 7.9 0.0 2.3 7.9 0.0 3.0 4 0 0 4 4 4 0 African swine fever virus J13L protein Drf_FH1 PF06346.12 CDJ68890.1 - 0.017 14.9 1.4 0.02 14.6 1.4 1.1 1 0 0 1 1 1 0 Formin Homology Region 1 DUF2997 PF11211.8 CDJ68891.1 - 0.017 14.9 0.7 0.036 13.8 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) SDA1 PF05285.12 CDJ68892.1 - 0.0017 17.9 11.9 0.0017 17.9 11.9 5.0 3 1 2 5 5 5 1 SDA1 SR-25 PF10500.9 CDJ68892.1 - 0.0017 18.0 9.9 0.0017 18.0 9.9 5.8 5 2 0 6 6 6 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ68892.1 - 0.0036 16.9 7.3 0.0036 16.9 7.3 3.5 3 0 0 3 3 3 1 Spt20 family ANAPC_CDC26 PF10471.9 CDJ68892.1 - 0.013 16.3 9.5 0.013 16.3 9.5 8.9 7 3 1 8 8 8 0 Anaphase-promoting complex APC subunit CDC26 Otopetrin PF03189.13 CDJ68892.1 - 5 5.8 5.2 15 4.2 5.2 1.8 1 0 0 1 1 1 0 Otopetrin EIF4E-T PF10477.9 CDJ68892.1 - 9.5 4.9 29.8 0.028 13.2 19.6 1.8 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E AF-4 PF05110.13 CDJ68893.1 - 0.0099 14.0 19.8 0.012 13.7 19.8 1.3 1 0 0 1 1 1 1 AF-4 proto-oncoprotein SPX PF03105.19 CDJ68893.1 - 0.042 13.8 14.5 0.048 13.6 14.5 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ68893.1 - 0.15 10.9 9.9 0.16 10.8 9.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Myc_N PF01056.18 CDJ68893.1 - 0.22 11.4 13.1 0.3 11.0 13.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Utp14 PF04615.13 CDJ68893.1 - 0.26 9.8 15.6 0.31 9.5 15.6 1.0 1 0 0 1 1 1 0 Utp14 protein Lin-8 PF03353.15 CDJ68893.1 - 0.28 10.7 7.9 0.31 10.5 7.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF755 PF05501.11 CDJ68893.1 - 0.3 11.4 23.9 0.52 10.6 23.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TFIIA PF03153.13 CDJ68893.1 - 0.43 10.5 19.0 0.52 10.2 19.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1635 PF07795.11 CDJ68893.1 - 0.43 10.4 10.1 0.62 9.9 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Menin PF05053.13 CDJ68893.1 - 0.57 8.5 19.6 0.67 8.3 19.6 1.1 1 0 0 1 1 1 0 Menin SARAF PF06682.12 CDJ68893.1 - 1 8.9 10.8 1.7 8.2 10.8 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4551 PF15087.6 CDJ68893.1 - 1.2 7.9 9.8 1.2 7.8 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOG2 PF10428.9 CDJ68893.1 - 2 7.5 19.3 2.2 7.4 19.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein ERM PF00769.19 CDJ68893.1 - 2 8.2 12.1 2.8 7.7 12.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Cwf_Cwc_15 PF04889.12 CDJ68893.1 - 2.5 7.8 13.1 3.7 7.2 13.1 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Smg8_Smg9 PF10220.9 CDJ68893.1 - 2.7 6.2 9.2 2.8 6.2 9.2 1.1 1 0 0 1 1 1 0 Smg8_Smg9 DUF1387 PF07139.11 CDJ68893.1 - 3 7.5 11.4 3.9 7.1 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF572 PF04502.13 CDJ68893.1 - 4.1 6.9 12.5 5.1 6.6 12.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S64 PF08192.11 CDJ68893.1 - 5.3 5.4 11.8 6.2 5.2 11.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 CDJ68893.1 - 5.9 5.4 11.9 5.8 5.5 11.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RAP1 PF07218.11 CDJ68893.1 - 7.7 4.7 18.2 12 4.1 18.2 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Spt20 PF12090.8 CDJ68893.1 - 9.2 5.8 13.8 14 5.2 13.8 1.2 1 0 0 1 1 1 0 Spt20 family GREB1 PF15782.5 CDJ68893.1 - 9.7 3.2 18.4 11 3.0 18.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3395 PF11875.8 CDJ68894.1 - 0.00042 20.2 21.6 0.00042 20.2 21.6 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3395) SUIM_assoc PF16619.5 CDJ68894.1 - 0.026 14.6 35.1 0.6 10.2 2.4 4.3 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 CDJ68894.1 - 0.2 12.7 3.5 1.4 9.9 2.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SR-25 PF10500.9 CDJ68896.1 - 0.0029 17.2 32.4 0.004 16.8 32.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 CDJ68896.1 - 0.059 13.2 15.7 0.069 13.0 15.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC106 PF15794.5 CDJ68896.1 - 0.1 12.3 20.4 0.13 12.0 20.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Med19 PF10278.9 CDJ68896.1 - 0.31 11.0 33.5 0.077 12.9 30.2 1.6 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.14 CDJ68896.1 - 0.38 9.0 19.4 0.44 8.8 19.4 1.0 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.12 CDJ68896.1 - 0.51 10.6 15.4 0.63 10.3 15.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MID_MedPIWI PF18296.1 CDJ68896.1 - 1 9.1 10.4 1.1 9.0 10.4 1.1 1 0 0 1 1 1 0 MID domain of medPIWI Dsh_C PF12316.8 CDJ68896.1 - 1.2 9.5 11.0 1.5 9.1 11.0 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal EOS1 PF12326.8 CDJ68896.1 - 1.3 9.0 6.6 1.6 8.6 6.6 1.3 1 0 0 1 1 1 0 N-glycosylation protein DUF3827 PF12877.7 CDJ68896.1 - 1.4 7.2 14.9 1.5 7.1 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF913 PF06025.12 CDJ68896.1 - 1.5 7.7 7.9 1.6 7.6 7.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Smg8_Smg9 PF10220.9 CDJ68896.1 - 3.9 5.7 14.8 4.7 5.4 14.8 1.0 1 0 0 1 1 1 0 Smg8_Smg9 GvpL_GvpF PF06386.11 CDJ68896.1 - 4.2 7.2 9.5 6.1 6.7 9.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Vfa1 PF08432.10 CDJ68896.1 - 4.8 7.5 28.0 2.6 8.4 26.1 1.4 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 CDJ68896.1 - 5.2 6.2 11.3 6.1 6.0 11.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FGF-BP1 PF06473.12 CDJ68896.1 - 5.7 6.7 23.6 9.5 6.0 23.6 1.3 1 1 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) XRN_M PF17846.1 CDJ68896.1 - 7.3 5.4 14.9 8.7 5.2 14.9 1.0 1 0 0 1 1 1 0 Xrn1 helical domain NPR3 PF03666.13 CDJ68896.1 - 9.9 4.8 18.4 12 4.6 18.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3896 PF13035.6 CDJ68897.1 - 0.85 9.8 2.6 2.3 8.4 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) DUF4602 PF15375.6 CDJ68898.1 - 0.17 12.2 0.2 0.17 12.2 0.2 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4602) TIP_N PF12457.8 CDJ68898.1 - 3.3 8.1 10.5 1.1 9.7 0.1 3.1 3 0 0 3 3 3 0 Tuftelin interacting protein N terminal IF-2B PF01008.17 CDJ68900.1 - 2.8e-20 72.7 0.0 3.4e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Apt1 PF10351.9 CDJ68900.1 - 0.038 12.9 1.0 0.039 12.8 1.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ68900.1 - 1.1 9.1 5.6 1.3 8.9 5.6 1.1 1 0 0 1 1 1 0 SPX domain WD40 PF00400.32 CDJ68901.1 - 2.5e-06 28.1 12.4 0.16 12.9 0.6 7.1 8 0 0 8 8 8 2 WD domain, G-beta repeat DUF2722 PF10846.8 CDJ68901.1 - 4.7e-05 22.5 48.5 0.0015 17.6 0.5 5.5 5 0 0 5 5 5 5 Protein of unknown function (DUF2722) HPS3_N PF14761.6 CDJ68901.1 - 0.0012 18.4 0.3 0.028 13.9 0.1 3.0 2 1 0 2 2 2 1 Hermansky-Pudlak syndrome 3 SUIM_assoc PF16619.5 CDJ68901.1 - 0.0013 18.8 1.5 0.0013 18.8 1.5 8.3 8 0 0 8 8 8 3 Unstructured region C-term to UIM in Ataxin3 TYW3 PF02676.14 CDJ68901.1 - 0.0087 15.5 0.3 0.0087 15.5 0.3 3.4 3 1 0 4 4 4 1 Methyltransferase TYW3 Lysis_col PF02402.16 CDJ68901.1 - 0.012 15.3 0.1 0.012 15.3 0.1 4.0 3 0 0 3 3 3 0 Lysis protein EF-1_beta_acid PF10587.9 CDJ68901.1 - 0.22 12.0 1.6 1.7 9.2 1.6 2.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region YdjM PF04307.14 CDJ68901.1 - 0.5 9.7 2.7 2.2 7.6 2.7 2.1 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase GOLD_2 PF13897.6 CDJ68901.1 - 1.1 9.7 5.9 0.3 11.6 0.6 2.8 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking BBS2_N PF14781.6 CDJ68901.1 - 3 7.8 17.2 8.2 6.4 0.9 5.5 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, N-terminal Utp14 PF04615.13 CDJ68902.1 - 0.00016 20.5 7.4 0.00016 20.5 7.4 1.8 1 1 1 2 2 2 1 Utp14 protein LMBR1 PF04791.16 CDJ68902.1 - 5 5.9 5.5 7.5 5.3 5.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein B9-C2 PF07162.11 CDJ68903.1 - 0.051 13.8 0.1 0.52 10.5 0.1 2.2 1 1 1 2 2 2 0 Ciliary basal body-associated, B9 protein SR-25 PF10500.9 CDJ68903.1 - 0.053 13.1 12.4 0.38 10.3 8.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ustilago_mating PF05722.12 CDJ68903.1 - 0.064 12.8 0.3 0.064 12.8 0.3 1.8 2 0 0 2 2 2 0 Ustilago B locus mating-type protein GTA_holin_3TM PF11351.8 CDJ68903.1 - 2.1 8.9 5.1 3.4 8.2 5.1 1.4 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release DUF3446 PF11928.8 CDJ68903.1 - 4.3 7.7 13.1 0.35 11.2 4.9 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain RskA PF10099.9 CDJ68904.1 - 0.0036 17.6 6.4 0.0062 16.8 6.4 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA ComX PF05952.12 CDJ68904.1 - 0.23 11.4 1.6 0.94 9.5 0.2 2.4 2 0 0 2 2 2 0 Bacillus competence pheromone ComX SUIM_assoc PF16619.5 CDJ68905.1 - 4e-09 36.4 0.7 3.1e-06 27.1 0.7 2.5 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ68905.1 - 2.7e-07 29.9 0.6 2.7e-07 29.9 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ68905.1 - 0.001 19.2 11.0 0.0012 18.9 11.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ68905.1 - 0.005 17.8 1.4 0.0094 16.9 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ68905.1 - 0.01 15.8 4.9 0.066 13.2 4.1 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) CLN3 PF02487.17 CDJ68905.1 - 0.058 12.4 0.8 0.08 12.0 0.8 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4647 PF15504.6 CDJ68905.1 - 0.081 12.0 5.3 0.12 11.4 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Presenilin PF01080.17 CDJ68905.1 - 0.091 11.5 0.6 0.14 10.9 0.3 1.4 2 0 0 2 2 2 0 Presenilin FHIPEP PF00771.20 CDJ68905.1 - 0.2 10.1 1.0 0.27 9.6 1.0 1.1 1 0 0 1 1 1 0 FHIPEP family DUF5421 PF17458.2 CDJ68905.1 - 0.2 11.0 9.1 0.28 10.5 9.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5421) CNDH2_M PF16869.5 CDJ68905.1 - 0.39 11.4 4.4 0.21 12.2 0.9 2.0 2 0 0 2 2 2 0 PF16858 Activator_LAG-3 PF11498.8 CDJ68905.1 - 0.53 9.2 25.6 0.72 8.8 25.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TMEM208_SND2 PF05620.11 CDJ68905.1 - 0.69 9.7 4.4 1.1 9.0 4.4 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 RRN9 PF10680.9 CDJ68905.1 - 2.9 8.2 5.9 4.3 7.7 4.5 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor CNDH2_N PF06278.11 CDJ68905.1 - 3 8.1 8.2 5.4 7.3 8.2 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Spt20 PF12090.8 CDJ68905.1 - 6.3 6.3 29.8 2.7 7.6 27.3 1.5 2 0 0 2 2 2 0 Spt20 family SepSecS PF05889.13 CDJ68907.1 - 2.6e-15 56.0 3.5 3.5e-07 29.3 0.0 2.7 2 1 1 3 3 3 2 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Presenilin PF01080.17 CDJ68907.1 - 0.00026 19.9 20.3 0.00026 19.9 20.3 2.0 2 0 0 2 2 2 1 Presenilin Pex14_N PF04695.13 CDJ68907.1 - 0.00081 20.1 36.5 0.00091 19.9 28.3 2.4 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.17 CDJ68907.1 - 0.0011 19.2 20.9 0.004 17.3 16.4 2.1 2 0 0 2 2 2 1 DDHD domain AIF_C PF14721.6 CDJ68907.1 - 0.011 16.1 20.6 0.023 15.1 2.8 3.0 2 1 1 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term AAA_11 PF13086.6 CDJ68907.1 - 0.022 14.6 22.6 0.014 15.2 16.8 2.0 2 0 0 2 2 2 0 AAA domain SLC12 PF03522.15 CDJ68907.1 - 0.028 13.4 23.2 0.025 13.6 20.2 1.8 2 0 0 2 2 2 0 Solute carrier family 12 TFIIA PF03153.13 CDJ68907.1 - 0.032 14.2 64.0 0.052 13.5 53.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit eIF3_subunit PF08597.10 CDJ68907.1 - 0.034 14.1 28.2 0.034 14.0 19.3 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit ALMT PF11744.8 CDJ68907.1 - 0.076 11.8 21.6 0.013 14.3 17.5 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter cwf18 PF08315.12 CDJ68907.1 - 0.12 13.0 25.6 0.16 12.7 18.5 2.1 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor Sporozoite_P67 PF05642.11 CDJ68907.1 - 0.13 10.3 15.0 0.17 9.9 15.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BORG_CEP PF14957.6 CDJ68907.1 - 0.15 13.3 15.8 0.31 12.2 11.9 2.1 2 0 0 2 2 2 0 Cdc42 effector DUF572 PF04502.13 CDJ68907.1 - 0.16 11.5 22.0 0.066 12.8 16.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) Tim54 PF11711.8 CDJ68907.1 - 0.18 10.5 20.9 0.017 13.9 14.0 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FAM60A PF15396.6 CDJ68907.1 - 0.19 11.7 18.5 0.085 12.8 14.2 1.9 2 0 0 2 2 2 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ68907.1 - 0.36 10.6 32.1 0.049 13.5 23.5 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Mem_trans PF03547.18 CDJ68907.1 - 0.55 8.6 3.4 0.55 8.6 3.4 1.2 1 0 0 1 1 1 0 Membrane transport protein Endostatin PF06482.11 CDJ68907.1 - 0.61 9.5 29.1 0.32 10.4 25.2 1.9 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Lin-8 PF03353.15 CDJ68907.1 - 0.67 9.5 31.5 0.77 9.3 25.1 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF4045 PF13254.6 CDJ68907.1 - 0.92 9.1 24.0 0.27 10.8 19.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) CSRNP_N PF16019.5 CDJ68907.1 - 1 9.3 23.1 7.8 6.3 21.1 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus PAT1 PF09770.9 CDJ68907.1 - 1 7.6 45.9 0.083 11.1 37.8 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4366 PF14283.6 CDJ68907.1 - 1.3 9.1 13.9 7.7 6.6 11.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Neur_chan_memb PF02932.16 CDJ68907.1 - 1.3 9.1 23.3 2.4 8.1 20.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LAP1C PF05609.12 CDJ68907.1 - 1.6 7.8 26.4 0.18 10.8 20.1 1.9 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Isy1 PF06246.12 CDJ68907.1 - 1.6 8.2 24.8 5.3 6.5 19.9 2.2 2 0 0 2 2 2 0 Isy1-like splicing family DUF4638 PF15472.6 CDJ68907.1 - 1.8 8.3 22.2 0.37 10.5 16.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) PIEZO PF15917.5 CDJ68907.1 - 1.9 7.9 30.9 9.1 5.7 26.9 2.1 2 0 0 2 2 2 0 Piezo TRAP_alpha PF03896.16 CDJ68907.1 - 2.2 7.4 15.6 0.85 8.8 12.6 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF3807 PF12720.7 CDJ68907.1 - 2.3 8.4 40.2 1 9.6 30.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF1387 PF07139.11 CDJ68907.1 - 2.5 7.7 28.4 0.49 10.1 21.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) PTPRCAP PF15713.5 CDJ68907.1 - 3.1 8.1 29.6 1.2 9.5 21.3 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated WTX PF09422.10 CDJ68907.1 - 3.1 6.7 20.7 0.96 8.4 15.2 2.0 2 0 0 2 2 2 0 WTX protein Cellulose_synt PF03552.14 CDJ68907.1 - 3.4 6.0 8.4 5 5.5 8.4 1.2 1 0 0 1 1 1 0 Cellulose synthase SpoIIP PF07454.11 CDJ68907.1 - 3.8 6.9 32.1 7.1 6.0 28.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF5580 PF17743.1 CDJ68907.1 - 4.6 5.7 21.7 0.24 9.9 15.6 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5580) DUF2052 PF09747.9 CDJ68907.1 - 5.1 7.2 29.4 3.6 7.7 23.1 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) MDM10 PF12519.8 CDJ68907.1 - 5.8 5.7 22.6 1.2 7.9 18.4 1.7 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 SOBP PF15279.6 CDJ68907.1 - 5.9 7.4 24.8 2 8.9 20.0 1.9 2 0 0 2 2 2 0 Sine oculis-binding protein MMU163 PF17119.5 CDJ68907.1 - 5.9 6.0 15.0 2.2 7.4 11.0 2.0 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis DUF3295 PF11702.8 CDJ68907.1 - 6.1 6.1 30.1 0.52 9.6 23.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) CCSAP PF15748.5 CDJ68907.1 - 6.7 6.8 35.5 1.2 9.3 27.1 2.0 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Methyltransf_32 PF13679.6 CDJ68907.1 - 6.8 6.7 21.9 52 3.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain PPP4R2 PF09184.11 CDJ68907.1 - 7.6 6.0 18.5 28 4.2 15.6 2.0 2 0 0 2 2 2 0 PPP4R2 DUF908 PF06012.12 CDJ68907.1 - 7.7 5.8 24.0 0.96 8.8 19.5 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) RNA_pol_Rpc4 PF05132.14 CDJ68907.1 - 8 6.9 28.5 4.4 7.7 22.3 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 Membralin PF09746.9 CDJ68907.1 - 8 5.4 19.2 0.31 10.1 13.6 1.4 2 0 0 2 2 2 0 Tumour-associated protein FAM176 PF14851.6 CDJ68907.1 - 8.1 6.1 19.1 32 4.1 15.2 2.4 2 0 0 2 2 2 0 FAM176 family Hydin_ADK PF17213.3 CDJ68907.1 - 9.4 6.5 27.2 36 4.5 23.7 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF5523 PF17661.1 CDJ68907.1 - 9.5 5.8 27.7 3 7.5 20.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) SPX PF03105.19 CDJ68908.1 - 0.014 15.3 0.8 0.017 15.1 0.8 1.0 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 CDJ68908.1 - 0.92 9.1 49.0 0.13 11.9 10.5 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ68908.1 - 7.7 7.3 37.4 0.72 10.6 4.8 3.4 3 0 0 3 3 3 0 Immortalisation up-regulated protein SNARE PF05739.19 CDJ68909.1 - 1.1e-07 31.7 0.0 2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CDJ68909.1 - 0.00014 21.6 0.3 0.0003 20.5 0.3 1.6 1 0 0 1 1 1 1 Syntaxin Prominin PF05478.11 CDJ68909.1 - 0.011 13.8 0.4 0.014 13.4 0.4 1.1 1 0 0 1 1 1 0 Prominin RPA_interact_M PF14767.6 CDJ68909.1 - 0.042 14.4 0.2 0.092 13.3 0.2 1.5 1 0 0 1 1 1 0 Replication protein A interacting middle TerB PF05099.13 CDJ68909.1 - 0.11 12.4 1.5 0.18 11.8 1.5 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TerB GSP_synth PF03738.14 CDJ68909.1 - 0.18 10.9 0.4 0.26 10.4 0.4 1.1 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp Spt20 PF12090.8 CDJ68910.1 - 0.16 11.6 34.0 0.079 12.6 11.9 3.3 3 0 0 3 3 3 0 Spt20 family TMV_coat PF00721.21 CDJ68910.1 - 0.27 11.1 3.4 11 5.9 0.0 2.8 2 0 0 2 2 2 0 Virus coat protein (TMV like) Thioredoxin PF00085.20 CDJ68911.1 - 3.2e-40 136.3 0.0 7.2e-22 77.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 CDJ68911.1 - 2e-10 40.9 0.0 6.9e-06 26.1 0.0 3.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CDJ68911.1 - 0.00032 21.1 0.0 0.095 13.2 0.0 3.0 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CDJ68911.1 - 0.0032 17.4 0.0 0.53 10.2 0.0 3.2 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CDJ68911.1 - 0.0062 16.8 0.0 4.2 7.8 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Mucin PF01456.17 CDJ68911.1 - 0.088 12.8 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PAP2 PF01569.21 CDJ68911.1 - 0.32 10.7 1.2 1 9.1 0.1 2.2 1 1 1 2 2 2 0 PAP2 superfamily RCC1 PF00415.18 CDJ68912.1 - 3.8e-67 222.7 36.4 2.6e-15 56.7 0.8 8.2 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ68912.1 - 1.9e-38 129.5 59.0 6.3e-09 35.4 3.4 8.6 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 CDJ68912.1 - 5.1e-05 23.1 0.3 3 7.5 0.0 4.6 5 0 0 5 5 5 2 TUP1-like enhancer of split Kelch_2 PF07646.15 CDJ68912.1 - 0.28 11.2 8.9 25 5.1 0.2 5.7 7 0 0 7 7 7 0 Kelch motif Ribosomal_L5e PF17144.4 CDJ68913.1 - 2e-81 271.8 0.3 2e-81 271.8 0.3 1.6 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CDJ68913.1 - 4.3e-31 107.7 6.1 4.3e-31 107.7 6.1 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF4853 PF16145.5 CDJ68913.1 - 0.037 14.2 0.2 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4853) DUF885 PF05960.11 CDJ68913.1 - 0.082 12.5 2.4 0.11 12.1 2.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) VitK2_biosynth PF02621.14 CDJ68913.1 - 0.16 11.5 0.4 0.27 10.7 0.4 1.4 1 0 0 1 1 1 0 Menaquinone biosynthesis DUF4820 PF16091.5 CDJ68914.1 - 0.045 13.1 7.6 0.063 12.6 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RNA_pol_Rbc25 PF08292.12 CDJ68914.1 - 0.21 11.9 7.0 0.64 10.3 0.3 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Jacalin PF01419.17 CDJ68914.1 - 0.62 10.0 0.0 0.62 10.0 0.0 1.6 2 0 0 2 2 2 0 Jacalin-like lectin domain Spt20 PF12090.8 CDJ68914.1 - 1.9 8.1 32.2 0.12 11.9 14.5 2.1 2 0 0 2 2 2 0 Spt20 family DUF1387 PF07139.11 CDJ68914.1 - 3 7.5 10.5 4 7.1 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Ndc1_Nup PF09531.10 CDJ68914.1 - 6.8 5.3 11.5 8.8 4.9 11.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ68914.1 - 9.3 4.9 7.1 12 4.5 7.1 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ68916.1 - 0.0097 15.5 5.0 0.0097 15.5 5.0 2.5 2 0 0 2 2 2 1 Spt20 family Peptidase_M48_N PF16491.5 CDJ68920.1 - 1.1e-55 188.4 1.8 1.3e-55 188.1 0.1 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CDJ68920.1 - 1.6e-40 139.0 0.0 2.1e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 CorA PF01544.18 CDJ68921.1 - 1.3e-05 24.6 0.1 1.3e-05 24.6 0.1 2.3 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF202 PF02656.15 CDJ68921.1 - 1 9.8 8.1 0.49 10.9 3.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) PTPRCAP PF15713.5 CDJ68921.1 - 1.2 9.4 32.1 0.77 10.0 6.5 2.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Eapp_C PF10238.9 CDJ68921.1 - 4 7.5 21.7 2.4 8.2 3.8 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4471 PF14740.6 CDJ68921.1 - 4.9 6.3 12.2 4.5 6.4 3.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Bud13 PF09736.9 CDJ68921.1 - 6.1 7.2 35.6 0.33 11.3 14.3 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex FAM76 PF16046.5 CDJ68921.1 - 10 5.4 25.7 5.3 6.3 9.9 2.3 2 0 0 2 2 2 0 FAM76 protein CEL_III_C PF18054.1 CDJ68922.1 - 0.17 11.9 7.4 0.26 11.3 7.4 1.1 1 0 0 1 1 1 0 CEL-III C-terminal DUF2722 PF10846.8 CDJ68922.1 - 0.31 9.9 7.0 0.45 9.4 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2722 PF10846.8 CDJ68923.1 - 0.00013 21.1 27.0 0.00048 19.2 9.9 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF2722) MAM33 PF02330.16 CDJ68923.1 - 0.05 13.6 6.5 1.5 8.7 1.0 2.4 2 0 0 2 2 2 0 Mitochondrial glycoprotein SAPS PF04499.15 CDJ68923.1 - 0.07 11.9 6.7 0.059 12.2 2.3 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF2828 PF11443.8 CDJ68923.1 - 0.16 10.0 8.6 0.27 9.3 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SLC12 PF03522.15 CDJ68923.1 - 1.3 7.9 13.5 0.15 11.1 6.9 2.1 2 0 0 2 2 2 0 Solute carrier family 12 SpoIIP PF07454.11 CDJ68923.1 - 6.8 6.1 17.7 1.3 8.5 3.1 2.8 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) SART-1 PF03343.13 CDJ68924.1 - 1.8e-12 46.7 20.3 4.6e-10 38.7 3.8 2.0 1 1 1 2 2 2 2 SART-1 family Ndc1_Nup PF09531.10 CDJ68924.1 - 0.066 11.9 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SpoIIIAH PF12685.7 CDJ68924.1 - 0.35 10.7 8.8 0.42 10.4 8.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein THOC2_N PF16134.5 CDJ68924.1 - 0.81 8.2 5.5 0.93 8.0 5.5 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Med3 PF11593.8 CDJ68924.1 - 2 7.5 19.3 2.6 7.1 19.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CCSAP PF15748.5 CDJ68924.1 - 2.2 8.4 11.9 3.1 7.9 11.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF966 PF06136.13 CDJ68924.1 - 3.3 7.3 9.4 3.9 7.1 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CiPC PF15800.5 CDJ68924.1 - 3.9 7.1 11.0 5.2 6.7 11.0 1.1 1 0 0 1 1 1 0 Clock interacting protein circadian DASH_Spc19 PF08287.11 CDJ68924.1 - 6.4 6.6 10.3 28 4.5 10.3 2.0 1 1 0 1 1 1 0 Spc19 Apt1 PF10351.9 CDJ68924.1 - 6.6 5.5 6.2 7.6 5.3 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MPP6 PF10175.9 CDJ68925.1 - 3.3e-05 24.4 2.3 6e-05 23.5 2.3 1.5 1 1 0 1 1 1 1 M-phase phosphoprotein 6 K_channel_TID PF07941.11 CDJ68925.1 - 0.002 18.5 7.7 0.002 18.5 7.7 2.3 2 0 0 2 2 2 1 Potassium channel Kv1.4 tandem inactivation domain Shadoo PF14999.6 CDJ68925.1 - 0.038 14.1 1.5 0.038 14.1 1.5 1.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective RskA PF10099.9 CDJ68925.1 - 0.19 12.0 14.2 0.3 11.3 14.2 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ68925.1 - 8 6.6 11.5 10 6.3 10.3 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cyt-b5 PF00173.28 CDJ68926.1 - 9.9e-06 25.6 0.0 6.1e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain PSCyt3 PF07627.11 CDJ68926.1 - 0.05 13.9 2.4 0.12 12.6 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) DUF4770 PF15994.5 CDJ68926.1 - 0.12 12.6 3.4 12 6.1 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) PsbQ PF05757.11 CDJ68926.1 - 0.42 10.3 3.9 1 9.0 3.9 1.7 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Ribosomal_60s PF00428.19 CDJ68926.1 - 0.58 10.8 19.2 0.17 12.5 15.7 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3446 PF11928.8 CDJ68926.1 - 6.6 7.1 17.1 0.13 12.6 2.4 2.8 2 1 0 2 2 2 0 Early growth response N-terminal domain TFIIA PF03153.13 CDJ68927.1 - 0.0053 16.8 46.6 0.0067 16.5 46.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ68927.1 - 0.017 14.1 27.1 0.023 13.7 27.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.6 CDJ68927.1 - 0.086 12.8 19.9 0.094 12.7 19.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CCSAP PF15748.5 CDJ68927.1 - 0.09 12.9 31.6 0.12 12.5 31.6 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PAT1 PF09770.9 CDJ68927.1 - 0.13 10.5 37.2 0.15 10.3 37.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Endostatin PF06482.11 CDJ68927.1 - 0.14 11.6 19.8 0.15 11.5 19.8 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin RR_TM4-6 PF06459.12 CDJ68927.1 - 0.21 11.4 28.8 0.3 10.9 28.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ68927.1 - 0.31 9.8 15.2 0.3 9.9 15.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Suf PF05843.14 CDJ68927.1 - 0.34 10.9 26.2 0.46 10.4 26.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF572 PF04502.13 CDJ68927.1 - 0.36 10.4 25.0 0.41 10.2 25.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2992 PF11208.8 CDJ68927.1 - 0.41 10.9 37.5 0.64 10.3 37.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) GAGA_bind PF06217.12 CDJ68927.1 - 0.44 10.8 22.2 0.52 10.5 22.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Nop53 PF07767.11 CDJ68927.1 - 0.5 9.7 47.8 0.61 9.4 47.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) VIR_N PF15912.5 CDJ68927.1 - 0.68 9.5 15.4 0.72 9.4 15.4 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Velvet PF11754.8 CDJ68927.1 - 0.69 9.8 19.3 0.91 9.4 19.3 1.3 1 0 0 1 1 1 0 Velvet factor BAF1_ABF1 PF04684.13 CDJ68927.1 - 0.88 8.6 25.0 1.3 8.0 25.0 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GREB1 PF15782.5 CDJ68927.1 - 0.94 6.5 26.0 1.1 6.3 26.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 CDJ68927.1 - 1.1 7.6 16.6 1.1 7.6 16.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 SLC12 PF03522.15 CDJ68927.1 - 1.2 8.1 25.2 1.4 7.9 25.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ68927.1 - 1.3 7.4 8.9 1.3 7.4 8.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 YL1 PF05764.13 CDJ68927.1 - 1.4 9.0 37.6 1.6 8.8 37.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Exonuc_VII_L PF02601.15 CDJ68927.1 - 1.5 8.3 23.9 1.8 8.1 23.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CLN3 PF02487.17 CDJ68927.1 - 2.1 7.3 15.4 2.4 7.1 15.4 1.2 1 0 0 1 1 1 0 CLN3 protein Peroxin-3 PF04882.12 CDJ68927.1 - 2.2 7.2 23.3 2.5 7.0 23.3 1.2 1 0 0 1 1 1 0 Peroxin-3 Hamartin PF04388.12 CDJ68927.1 - 2.9 6.5 21.4 2.8 6.5 21.4 1.1 1 0 0 1 1 1 0 Hamartin protein SAPS PF04499.15 CDJ68927.1 - 3 6.5 17.7 3.2 6.4 17.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC27 PF09507.10 CDJ68927.1 - 3.2 7.0 35.6 3.9 6.8 35.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 LAP1C PF05609.12 CDJ68927.1 - 3.9 6.5 28.3 4.3 6.3 28.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Activator_LAG-3 PF11498.8 CDJ68927.1 - 4.5 6.1 61.6 6.2 5.7 61.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HemX PF04375.14 CDJ68927.1 - 7.1 5.8 44.4 10 5.3 44.4 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SprA-related PF12118.8 CDJ68927.1 - 7.6 5.6 46.4 11 5.1 46.4 1.2 1 0 0 1 1 1 0 SprA-related family Auxin_canalis PF05703.11 CDJ68928.1 - 0.061 13.2 8.6 0.084 12.8 8.6 1.1 1 0 0 1 1 1 0 Auxin canalisation MCM3AP_GANP PF16769.5 CDJ68928.1 - 0.097 10.9 25.3 0.11 10.7 25.3 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP IZUMO PF15005.6 CDJ68928.1 - 0.37 11.3 25.1 0.49 10.9 25.1 1.1 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated V_ATPase_I PF01496.19 CDJ68928.1 - 1.6 6.6 22.6 1.9 6.3 22.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL92 PF03048.14 CDJ68928.1 - 2.7 7.7 7.6 3.2 7.5 7.6 1.1 1 0 0 1 1 1 0 UL92 family 2HCT PF03390.15 CDJ68928.1 - 2.8 6.4 6.8 3.7 6.1 6.8 1.0 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Presenilin PF01080.17 CDJ68928.1 - 3.7 6.2 14.4 4.4 6.0 14.4 1.1 1 0 0 1 1 1 0 Presenilin PCRF PF03462.18 CDJ68928.1 - 4.5 7.1 20.0 5.6 6.8 20.0 1.1 1 0 0 1 1 1 0 PCRF domain FmiP_Thoc5 PF09766.9 CDJ68928.1 - 5.7 6.1 37.1 7.6 5.7 37.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Peptidase_S46 PF10459.9 CDJ68928.1 - 7.5 5.1 18.4 8.2 4.9 18.4 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF1645 PF07816.11 CDJ68929.1 - 0.0072 16.9 1.9 0.012 16.2 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ68929.1 - 0.0097 15.5 4.6 0.0097 15.5 4.6 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ68929.1 - 0.089 12.4 4.3 0.12 12.0 4.3 1.2 1 0 0 1 1 1 0 Spt20 family WAC_Acf1_DNA_bd PF10537.9 CDJ68930.1 - 0.027 15.0 1.4 0.065 13.8 0.3 2.0 1 1 1 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal UPF0128 PF03673.13 CDJ68930.1 - 0.22 11.0 2.9 3.3 7.1 0.1 2.1 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0128) 2OG-FeII_Oxy_3 PF13640.6 CDJ68931.1 - 5.1e-05 24.1 0.0 9.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 CDJ68931.1 - 0.0022 18.6 0.0 0.0042 17.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Caldesmon PF02029.15 CDJ68932.1 - 0.0055 15.5 45.3 0.014 14.2 45.3 1.7 1 0 0 1 1 1 1 Caldesmon Mem_trans PF03547.18 CDJ68932.1 - 0.1 11.0 0.9 0.15 10.5 0.9 1.5 1 0 0 1 1 1 0 Membrane transport protein Transket_pyr PF02779.24 CDJ68933.1 - 2.7e-31 108.6 0.1 4.3e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain MIF4G PF02854.19 CDJ68935.1 - 1.7e-19 70.3 0.0 2.3e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain DUF2722 PF10846.8 CDJ68936.1 - 0.0053 15.8 2.7 0.0053 15.8 2.7 3.5 4 1 0 4 4 4 1 Protein of unknown function (DUF2722) IF-2B PF01008.17 CDJ68938.1 - 4.7e-16 58.8 0.0 5.2e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF2228 PF10228.9 CDJ68939.1 - 0.00024 20.9 0.1 0.00024 20.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) hDGE_amylase PF14701.6 CDJ68940.1 - 4.8e-102 342.3 0.2 1.4e-50 172.7 0.3 2.5 1 1 0 2 2 2 2 Glycogen debranching enzyme, glucanotransferase domain hGDE_central PF14702.6 CDJ68940.1 - 3.3e-33 115.4 0.1 4e-32 111.9 0.0 2.3 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme GDE_C PF06202.14 CDJ68940.1 - 3.7e-21 75.5 0.0 9.4e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase AMPK1_CBM PF16561.5 CDJ68940.1 - 2.6e-17 62.8 1.0 1.6e-15 57.1 0.1 2.9 3 1 0 3 3 3 1 Glycogen recognition site of AMP-activated protein kinase DUF2722 PF10846.8 CDJ68940.1 - 0.00096 18.2 1.8 0.00096 18.2 1.8 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) DUF2339 PF10101.9 CDJ68941.1 - 2.2e-05 23.3 11.3 2.5e-05 23.1 11.3 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Hamartin PF04388.12 CDJ68941.1 - 0.55 8.8 34.7 0.71 8.5 34.7 1.2 1 0 0 1 1 1 0 Hamartin protein V_ATPase_I PF01496.19 CDJ68941.1 - 0.83 7.5 39.2 1.1 7.0 39.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SOBP PF15279.6 CDJ68941.1 - 1.1 9.8 36.7 1.6 9.3 36.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.9 CDJ68941.1 - 1.2 7.3 73.3 1.5 7.0 73.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC27 PF09507.10 CDJ68941.1 - 1.3 8.4 44.4 2 7.7 44.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hid1 PF12722.7 CDJ68941.1 - 2.7 6.0 39.4 3 5.8 39.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF5585 PF17823.1 CDJ68941.1 - 5.3 5.9 29.7 6.4 5.6 29.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Asp-B-Hydro_N PF05279.11 CDJ68941.1 - 9.8 6.2 32.3 13 5.8 32.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RNB PF00773.19 CDJ68942.1 - 1.1e-27 97.3 2.0 8.7e-18 64.7 2.8 2.9 2 1 0 2 2 2 2 RNB domain SPX PF03105.19 CDJ68942.1 - 0.0027 17.7 19.9 0.0039 17.2 19.9 1.2 1 0 0 1 1 1 1 SPX domain TFIIA PF03153.13 CDJ68942.1 - 0.0057 16.7 18.7 0.0083 16.2 18.7 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ68942.1 - 0.0091 14.6 14.2 0.013 14.1 14.2 1.3 1 0 0 1 1 1 1 Macoilin family Menin PF05053.13 CDJ68942.1 - 0.017 13.5 12.6 0.023 13.1 12.6 1.1 1 0 0 1 1 1 0 Menin RAP1 PF07218.11 CDJ68942.1 - 0.032 12.5 12.8 0.039 12.2 12.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Lin-8 PF03353.15 CDJ68942.1 - 0.71 9.4 15.0 1.4 8.4 15.0 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CCDC53 PF10152.9 CDJ68942.1 - 1.2 9.6 14.1 3.9 7.9 0.8 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SAPS PF04499.15 CDJ68942.1 - 1.7 7.3 8.7 2.5 6.8 8.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RskA PF10099.9 CDJ68942.1 - 2.5 8.4 14.7 1.4 9.2 11.7 1.9 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Secretin_N_2 PF07655.13 CDJ68942.1 - 3.1 8.4 31.9 1.6 9.3 27.9 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Presenilin PF01080.17 CDJ68943.1 - 0.22 10.2 12.0 0.27 10.0 12.0 1.1 1 0 0 1 1 1 0 Presenilin Paramyxo_ncap PF00973.19 CDJ68943.1 - 1.1 8.1 9.8 0.72 8.7 8.5 1.3 1 1 0 1 1 1 0 Paramyxovirus nucleocapsid protein FHIPEP PF00771.20 CDJ68943.1 - 4.1 5.8 14.4 7.3 4.9 8.1 2.1 1 1 0 2 2 2 0 FHIPEP family Rxt3 PF08642.10 CDJ68943.1 - 9.5 7.0 7.9 8.2 7.2 4.7 2.0 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Ribosomal_60s PF00428.19 CDJ68944.1 - 0.7 10.5 3.6 0.55 10.8 0.2 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sin_N PF04801.13 CDJ68945.1 - 0.0022 17.3 12.3 0.0022 17.3 12.3 3.8 3 1 1 4 4 4 1 Sin-like protein conserved region DUF4079 PF13301.6 CDJ68945.1 - 0.0062 16.7 0.0 2.9 8.0 0.0 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF4079) RCR PF12273.8 CDJ68945.1 - 7 7.3 16.7 0.034 14.8 1.9 3.5 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red Flavi_glycoprot PF00869.20 CDJ68948.1 - 0.03 13.6 0.5 0.04 13.1 0.5 1.2 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains DUF3331 PF11811.8 CDJ68948.1 - 3.4 7.6 5.7 4.3 7.3 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3331) Trehalase PF01204.18 CDJ68950.1 - 1.1e-64 219.2 0.1 1.4e-64 218.8 0.1 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 CDJ68950.1 - 3.3e-06 26.3 0.2 5.1e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase PP2C PF00481.21 CDJ68951.1 - 9.3e-36 123.8 0.0 1.3e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ68951.1 - 1.9e-06 27.9 0.0 3.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CDJ68951.1 - 2e-05 24.3 0.0 0.0031 17.2 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C 4HBT_3 PF13622.6 CDJ68952.1 - 0.0091 16.3 3.0 0.0096 16.2 2.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily CSD PF00313.22 CDJ68953.1 - 6.5e-24 83.6 0.4 9e-24 83.1 0.4 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 CDJ68953.1 - 0.00064 19.4 0.8 0.0016 18.1 0.8 1.7 1 1 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.23 CDJ68953.1 - 0.11 12.9 0.1 0.17 12.3 0.1 1.2 1 0 0 1 1 1 0 S1 RNA binding domain Anticodon_1 PF08264.13 CDJ68954.1 - 0.00037 20.5 0.0 0.00045 20.2 0.0 1.1 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA SUIM_assoc PF16619.5 CDJ68954.1 - 0.0012 18.9 6.4 0.0034 17.4 6.4 2.0 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Androgen_recep PF02166.16 CDJ68954.1 - 0.0046 15.9 6.2 0.0059 15.5 6.2 1.2 1 0 0 1 1 1 1 Androgen receptor ANAPC_CDC26 PF10471.9 CDJ68954.1 - 0.062 14.1 9.9 0.09 13.6 9.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CDJ68954.1 - 0.095 12.3 11.5 0.12 12.0 11.5 1.1 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ68954.1 - 1.8 7.6 7.0 2.7 7.0 7.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein RskA PF10099.9 CDJ68955.1 - 0.0011 19.4 6.8 0.0011 19.4 6.8 9.9 1 1 6 9 9 9 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ68955.1 - 0.0011 18.7 14.6 0.0011 18.7 14.6 6.4 5 2 0 5 5 5 2 Spt20 family Tub_N PF16322.5 CDJ68955.1 - 0.0054 17.2 11.8 0.0054 17.2 11.8 5.2 4 2 0 4 4 4 1 Tubby N-terminal SPX PF03105.19 CDJ68955.1 - 0.0071 16.3 9.7 0.0071 16.3 9.7 4.1 4 1 0 4 4 4 2 SPX domain DUF1077 PF06417.12 CDJ68956.1 - 2.6e-12 46.8 0.0 4.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) SUIM_assoc PF16619.5 CDJ68956.1 - 0.0075 16.3 2.5 0.012 15.6 2.5 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF3138 PF11336.8 CDJ68956.1 - 0.032 12.8 10.7 0.042 12.5 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_60s PF00428.19 CDJ68956.1 - 0.72 10.5 14.3 1.5 9.5 14.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.25 CDJ68957.1 - 0.0006 19.3 0.0 0.0006 19.3 0.0 4.3 4 2 0 5 5 5 1 Protein kinase domain DUF755 PF05501.11 CDJ68957.1 - 0.00091 19.5 17.1 0.00091 19.5 17.1 16.4 10 3 6 17 17 17 1 Domain of unknown function (DUF755) PHF5 PF03660.14 CDJ68959.1 - 5.2e-50 168.0 12.7 6.4e-50 167.7 12.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 CDJ68959.1 - 0.22 9.3 7.9 0.24 9.2 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 SET PF00856.28 CDJ68960.1 - 5.9e-20 72.3 0.0 5.9e-20 72.3 0.0 4.2 3 2 0 3 3 3 1 SET domain TFIIA PF03153.13 CDJ68960.1 - 0.002 18.2 30.0 0.002 18.2 30.0 4.4 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Phage_cap_P2 PF05125.12 CDJ68964.1 - 0.1 11.6 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Phage major capsid protein, P2 family Phage_GPD PF05954.11 CDJ68964.1 - 0.11 11.8 0.5 0.12 11.6 0.5 1.0 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) FH2 PF02181.23 CDJ68965.1 - 6.2e-39 134.2 0.0 7.1e-27 94.5 0.0 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain OST-HTH PF12872.7 CDJ68966.1 - 0.00032 20.5 0.0 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Bromodomain PF00439.25 CDJ68967.1 - 9.2e-22 76.9 0.3 1.9e-21 75.9 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 CDJ68967.1 - 2.5e-11 43.8 0.1 6.2e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ68967.1 - 6.3e-09 35.8 0.1 1.1e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ68967.1 - 6.9e-07 29.6 0.8 1.5e-06 28.5 0.8 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PCAF_N PF06466.11 CDJ68967.1 - 0.0038 16.8 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Acetyltransf_9 PF13527.7 CDJ68967.1 - 0.011 15.9 0.1 0.06 13.4 0.1 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ68967.1 - 0.011 15.7 0.0 0.032 14.2 0.0 1.9 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 CDJ68967.1 - 0.095 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PsbQ PF05757.11 CDJ68967.1 - 0.63 9.7 2.0 1.2 8.8 1.5 1.7 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Ribosomal_L3 PF00297.22 CDJ68968.1 - 8.2e-11 41.5 3.2 3.3e-08 32.9 2.7 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 FAM163 PF15069.6 CDJ68971.1 - 0.04 14.4 0.4 0.078 13.4 0.0 1.6 2 0 0 2 2 2 0 FAM163 family DUF948 PF06103.11 CDJ68971.1 - 0.36 11.1 1.6 0.74 10.1 1.6 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3273 PF11677.8 CDJ68973.1 - 1.5e-95 319.5 4.4 1.7e-95 319.3 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF2569 PF10754.9 CDJ68973.1 - 0.16 12.4 5.3 0.29 11.6 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) Tetraspanin PF00335.20 CDJ68973.1 - 6.4 6.4 8.5 80 2.8 6.3 2.9 1 1 1 2 2 2 0 Tetraspanin family UQ_con PF00179.26 CDJ68974.1 - 4.5e-39 133.3 0.1 6.1e-39 132.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ68974.1 - 0.043 13.5 0.2 0.1 12.3 0.1 1.7 1 1 1 2 2 2 0 Prokaryotic E2 family B PDZ_3 PF17815.1 CDJ68975.1 - 3.2e-45 153.6 0.0 5.9e-45 152.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 CDJ68975.1 - 3.1e-18 67.1 0.3 5.9e-18 66.2 0.3 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CDJ68975.1 - 1.7e-12 47.6 0.4 2.9e-12 46.9 0.4 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 CDJ68975.1 - 1.3e-08 35.0 0.1 7.8e-07 29.3 0.0 3.0 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 CDJ68975.1 - 1.4e-05 24.8 0.2 0.018 14.9 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 CDJ68975.1 - 0.0025 18.1 0.0 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 CDJ68975.1 - 0.053 12.2 0.0 0.077 11.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S7 PF00949.21 CDJ68975.1 - 0.075 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease SUIM_assoc PF16619.5 CDJ68977.1 - 0.0059 16.6 9.2 0.58 10.3 1.9 2.7 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ68978.1 - 4.2e-05 22.7 15.8 4.7e-05 22.5 15.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ68978.1 - 0.00055 20.0 6.6 0.00055 20.0 6.6 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF3464 PF11947.8 CDJ68978.1 - 0.002 17.9 2.0 0.0021 17.8 2.0 1.2 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 DUF4834 PF16118.5 CDJ68978.1 - 0.0028 18.6 5.9 0.0043 18.0 5.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) MecA PF05389.12 CDJ68978.1 - 0.003 17.2 1.7 0.0031 17.2 1.7 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) Presenilin PF01080.17 CDJ68978.1 - 0.0033 16.3 2.1 0.0034 16.2 2.1 1.1 1 0 0 1 1 1 1 Presenilin TFIIA PF03153.13 CDJ68978.1 - 0.0039 17.2 20.8 0.0039 17.2 20.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ68978.1 - 0.0042 15.9 20.3 0.0042 15.9 20.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.17 CDJ68978.1 - 0.0042 17.3 1.3 0.0042 17.3 1.3 1.1 1 0 0 1 1 1 1 DDHD domain Connexin PF00029.19 CDJ68978.1 - 0.0046 16.7 1.1 0.0049 16.7 1.1 1.1 1 0 0 1 1 1 1 Connexin Smg4_UPF3 PF03467.15 CDJ68978.1 - 0.0051 16.8 4.2 0.008 16.2 4.2 1.2 1 0 0 1 1 1 1 Smg-4/UPF3 family SpoIIP PF07454.11 CDJ68978.1 - 0.0054 16.2 4.2 0.0065 16.0 4.2 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) FHIPEP PF00771.20 CDJ68978.1 - 0.0054 15.3 1.6 0.0057 15.2 1.6 1.0 1 0 0 1 1 1 1 FHIPEP family DUF3405 PF11885.8 CDJ68978.1 - 0.0055 15.4 3.2 0.0059 15.3 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) EIIBC-GUT_N PF03612.14 CDJ68978.1 - 0.0059 16.4 2.6 0.0072 16.1 2.6 1.2 1 0 0 1 1 1 1 Sorbitol phosphotransferase enzyme II N-terminus MMU163 PF17119.5 CDJ68978.1 - 0.012 14.8 0.4 0.013 14.7 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis RAB3GAP2_C PF14656.6 CDJ68978.1 - 0.012 13.9 4.3 0.014 13.6 4.3 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus eIF-3_zeta PF05091.12 CDJ68978.1 - 0.015 14.3 7.6 0.015 14.3 7.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 CDJ68978.1 - 0.019 14.3 4.6 0.02 14.3 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM176 PF14851.6 CDJ68978.1 - 0.019 14.6 0.3 0.023 14.4 0.3 1.1 1 0 0 1 1 1 0 FAM176 family Glyco_hydro_1 PF00232.18 CDJ68978.1 - 0.019 13.4 0.1 0.019 13.4 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Band_3_cyto PF07565.13 CDJ68978.1 - 0.02 14.7 3.1 0.018 14.8 3.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain UPF0560 PF10577.9 CDJ68978.1 - 0.023 13.2 7.9 0.022 13.3 7.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4175 PF13779.6 CDJ68978.1 - 0.025 12.5 18.7 0.025 12.5 18.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TERB2 PF15101.6 CDJ68978.1 - 0.027 14.5 8.4 0.029 14.4 8.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RICTOR_N PF14664.6 CDJ68978.1 - 0.03 13.3 1.9 0.031 13.3 1.9 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF2828 PF11443.8 CDJ68978.1 - 0.033 12.3 2.3 0.036 12.2 2.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) V_ATPase_I PF01496.19 CDJ68978.1 - 0.035 12.0 3.2 0.036 12.0 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Folate_carrier PF01770.18 CDJ68978.1 - 0.036 12.8 0.6 0.038 12.7 0.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.20 CDJ68978.1 - 0.04 12.2 1.6 0.043 12.1 1.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peroxin-13_N PF04088.13 CDJ68978.1 - 0.04 14.2 1.3 0.049 13.9 1.3 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Rpp20 PF12328.8 CDJ68978.1 - 0.045 13.7 3.2 0.053 13.5 3.2 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Neur_chan_memb PF02932.16 CDJ68978.1 - 0.045 13.8 1.9 0.045 13.8 1.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region G0-G1_switch_2 PF15103.6 CDJ68978.1 - 0.046 14.2 2.8 0.055 13.9 2.8 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 EOS1 PF12326.8 CDJ68978.1 - 0.048 13.6 0.6 0.054 13.4 0.6 1.2 1 0 0 1 1 1 0 N-glycosylation protein FAM150 PF15129.6 CDJ68978.1 - 0.06 13.5 4.0 0.084 13.0 4.0 1.3 1 0 0 1 1 1 0 FAM150 family Orf78 PF06024.12 CDJ68978.1 - 0.065 13.5 3.7 0.11 12.8 3.7 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF1980 PF09323.10 CDJ68978.1 - 0.072 13.0 0.6 0.078 12.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Ctr PF04145.15 CDJ68978.1 - 0.08 13.6 0.9 0.088 13.4 0.9 1.2 1 0 0 1 1 1 0 Ctr copper transporter family PepSY_TM PF03929.16 CDJ68978.1 - 0.095 12.3 0.8 0.1 12.3 0.8 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Het-C PF07217.11 CDJ68978.1 - 0.099 11.2 3.7 0.096 11.2 3.7 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C CLN3 PF02487.17 CDJ68978.1 - 0.11 11.6 1.7 0.11 11.5 1.7 1.1 1 0 0 1 1 1 0 CLN3 protein DUF1682 PF07946.14 CDJ68978.1 - 0.11 11.7 4.7 0.12 11.5 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) EPL1 PF10513.9 CDJ68978.1 - 0.11 12.9 7.0 0.14 12.5 7.0 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like WASH-7_C PF14746.6 CDJ68978.1 - 0.12 12.1 5.5 0.18 11.5 5.5 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal GET2 PF08690.10 CDJ68978.1 - 0.14 11.8 8.5 0.16 11.6 8.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Folliculin PF11704.8 CDJ68978.1 - 0.14 12.0 4.2 0.18 11.6 4.2 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport CSG2 PF16965.5 CDJ68978.1 - 0.15 10.9 0.6 0.14 11.1 0.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator CobT PF06213.12 CDJ68978.1 - 0.18 11.2 11.7 0.23 10.8 11.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ALMT PF11744.8 CDJ68978.1 - 0.18 10.6 2.0 0.2 10.4 2.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PepSY_TM_like_2 PF16357.5 CDJ68978.1 - 0.19 11.7 2.1 0.31 11.0 2.1 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like PigN PF04987.14 CDJ68978.1 - 0.19 10.5 2.0 0.21 10.4 2.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Plasmodium_Vir PF05795.11 CDJ68978.1 - 0.2 11.0 1.4 0.2 11.0 1.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ABC2_membrane_2 PF12679.7 CDJ68978.1 - 0.26 10.6 1.1 0.27 10.5 1.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Ufd2P_core PF10408.9 CDJ68978.1 - 0.28 9.7 8.3 0.29 9.7 8.3 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core MENTAL PF10457.9 CDJ68978.1 - 0.28 11.0 1.3 0.39 10.5 1.3 1.1 1 0 0 1 1 1 0 Cholesterol-capturing domain Ureide_permease PF07168.11 CDJ68978.1 - 0.28 9.9 0.8 0.32 9.7 0.8 1.1 1 0 0 1 1 1 0 Ureide permease baeRF_family10 PF18854.1 CDJ68978.1 - 0.29 11.4 6.8 0.43 10.8 6.8 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 DUF775 PF05603.12 CDJ68978.1 - 0.33 10.4 8.6 0.44 10.1 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) EMC3_TMCO1 PF01956.16 CDJ68978.1 - 0.34 10.6 5.7 0.42 10.3 5.7 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Serinc PF03348.15 CDJ68978.1 - 0.35 9.8 1.4 0.35 9.7 1.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TMEM51 PF15345.6 CDJ68978.1 - 0.35 10.7 9.4 0.46 10.3 9.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Glt_symporter PF03616.14 CDJ68978.1 - 0.37 9.4 0.9 0.41 9.3 0.9 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DcuA_DcuB PF03605.14 CDJ68978.1 - 0.4 9.5 0.7 0.41 9.5 0.7 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter AIF_C PF14721.6 CDJ68978.1 - 0.63 10.4 5.9 0.89 9.9 5.9 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2367 PF10164.9 CDJ68978.1 - 0.63 10.6 3.1 1 9.9 3.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) RNA_pol_Rbc25 PF08292.12 CDJ68978.1 - 0.64 10.3 5.6 0.92 9.7 5.6 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Sec62 PF03839.16 CDJ68978.1 - 0.66 9.5 4.4 0.86 9.1 4.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 YhfC PF10086.9 CDJ68978.1 - 0.67 9.3 3.3 1.2 8.5 3.3 1.3 1 0 0 1 1 1 0 YhfC intramembrane metalloprotease Kei1 PF08552.11 CDJ68978.1 - 0.77 9.6 2.6 0.97 9.3 2.6 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RR_TM4-6 PF06459.12 CDJ68978.1 - 1.7 8.4 9.0 2.4 7.9 9.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex26 PF07163.12 CDJ68978.1 - 2 7.7 15.9 1.6 7.9 14.8 1.4 1 1 1 2 2 2 0 Pex26 protein DUF2368 PF10166.9 CDJ68978.1 - 2.5 7.7 14.0 3.8 7.1 12.8 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) FlaG PF03646.15 CDJ68978.1 - 2.5 8.3 17.2 3.9 7.7 17.2 1.3 1 0 0 1 1 1 0 FlaG protein EphA2_TM PF14575.6 CDJ68978.1 - 8.2 7.4 5.7 17 6.4 5.7 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Coilin_N PF15862.5 CDJ68978.1 - 8.3 6.2 15.8 13 5.6 15.8 1.2 1 0 0 1 1 1 0 Coilin N-terminus Fcf1 PF04900.12 CDJ68979.1 - 4.8e-10 39.7 5.1 2.4e-05 24.6 0.1 2.8 2 0 0 2 2 2 2 Fcf1 SUIM_assoc PF16619.5 CDJ68979.1 - 0.0029 17.6 3.2 0.0029 17.6 3.2 3.2 2 1 1 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ68979.1 - 0.029 14.0 20.2 0.27 10.8 11.3 2.3 2 0 0 2 2 2 0 Spt20 family PIN_9 PF18477.1 CDJ68979.1 - 0.063 13.6 2.1 2.7 8.3 0.0 3.1 2 1 1 3 3 3 0 PIN like domain DUF508 PF04370.12 CDJ68979.1 - 1.4 8.7 14.5 2.7 7.7 9.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF508) GREB1 PF15782.5 CDJ68979.1 - 2 5.4 24.0 2.7 5.0 24.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MFS_1 PF07690.16 CDJ68980.1 - 2.1e-10 40.1 5.2 3e-08 33.0 4.2 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Presenilin PF01080.17 CDJ68980.1 - 5.8e-05 22.0 0.7 0.073 11.8 0.0 2.4 2 0 0 2 2 2 2 Presenilin SUIM_assoc PF16619.5 CDJ68980.1 - 0.0017 18.4 0.0 0.0017 18.4 0.0 3.6 2 1 1 3 3 1 1 Unstructured region C-term to UIM in Ataxin3 DUF2140 PF09911.9 CDJ68980.1 - 0.0084 15.7 1.8 0.0097 15.5 0.4 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2140) OATP PF03137.20 CDJ68980.1 - 0.021 13.1 13.5 0.14 10.4 0.1 3.1 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Suf PF05843.14 CDJ68980.1 - 0.034 14.1 4.5 0.27 11.2 2.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ68980.1 - 0.062 13.3 19.0 0.12 12.4 14.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ68980.1 - 0.35 10.7 22.8 0.028 14.3 12.1 2.2 2 0 0 2 2 2 0 SPX domain V_ATPase_I PF01496.19 CDJ68980.1 - 0.46 8.3 3.1 0.83 7.5 3.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Apt1 PF10351.9 CDJ68980.1 - 0.73 8.6 21.6 0.021 13.7 13.0 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain EPL1 PF10513.9 CDJ68980.1 - 1.3 9.3 6.8 4.2 7.7 2.6 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like SOG2 PF10428.9 CDJ68980.1 - 2.9 7.0 24.6 0.21 10.7 16.9 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Ctr PF04145.15 CDJ68980.1 - 3.2 8.4 9.3 20 5.8 0.4 3.1 2 1 0 2 2 2 0 Ctr copper transporter family FAM176 PF14851.6 CDJ68980.1 - 3.3 7.3 5.7 0.38 10.4 0.1 2.2 2 1 0 2 2 2 0 FAM176 family KdgT PF03812.13 CDJ68980.1 - 4.5 6.5 12.3 0.29 10.4 1.7 2.2 2 0 0 2 2 2 0 2-keto-3-deoxygluconate permease DUF572 PF04502.13 CDJ68980.1 - 4.6 6.8 8.1 7.9 6.0 1.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) EMC3_TMCO1 PF01956.16 CDJ68980.1 - 5.7 6.6 5.5 11 5.7 5.5 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CobT PF06213.12 CDJ68980.1 - 8.2 5.7 11.5 0.57 9.5 2.8 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RskA PF10099.9 CDJ68980.1 - 9.6 6.5 29.1 1.7e+02 2.4 27.1 3.2 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ68981.1 - 0.002 17.8 11.8 0.002 17.8 11.8 2.9 2 1 0 2 2 2 1 Spt20 family DUF3446 PF11928.8 CDJ68981.1 - 0.021 15.1 4.3 0.021 15.1 4.3 3.9 3 1 0 3 3 3 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ68981.1 - 0.097 12.3 30.8 0.47 10.0 1.8 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein INSIG PF07281.12 CDJ68981.1 - 0.26 10.9 7.3 0.53 9.9 1.4 2.7 2 1 0 2 2 2 0 Insulin-induced protein (INSIG) DNApol_Exo PF18136.1 CDJ68981.1 - 4 6.5 16.0 0.056 12.6 4.0 2.2 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain DUF2681 PF10883.8 CDJ68981.1 - 8.1 6.9 36.3 0.53 10.7 7.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) CSD PF00313.22 CDJ68982.1 - 4e-05 23.4 0.0 0.00013 21.8 0.0 1.9 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 CDJ68982.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain SPX PF03105.19 CDJ68983.1 - 0.0011 19.0 26.1 0.009 16.0 18.2 2.2 2 0 0 2 2 2 2 SPX domain Filamin PF00630.19 CDJ68983.1 - 0.012 16.5 0.0 0.026 15.3 0.0 1.6 1 0 0 1 1 1 0 Filamin/ABP280 repeat Velvet PF11754.8 CDJ68983.1 - 0.71 9.8 16.0 0.66 9.9 8.1 2.9 3 0 0 3 3 3 0 Velvet factor Kinesin PF00225.23 CDJ68984.1 - 2.7e-72 243.5 0.0 2.7e-72 243.5 0.0 5.8 5 1 0 6 6 6 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ68984.1 - 1.3e-15 57.6 0.0 1.3e-15 57.6 0.0 4.5 6 2 1 7 7 7 1 Microtubule binding TFIID_NTD2 PF04494.15 CDJ68985.1 - 0.016 15.4 0.2 0.016 15.4 0.2 2.1 3 0 0 3 3 3 0 WD40 associated region in TFIID subunit, NTD2 domain TFIIA PF03153.13 CDJ68985.1 - 0.031 14.3 57.0 0.11 12.5 38.5 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PSI_PsaF PF02507.15 CDJ68985.1 - 0.05 13.4 3.9 0.1 12.5 3.9 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Init_tRNA_PT PF04179.12 CDJ68985.1 - 0.11 12.8 2.8 0.28 11.5 2.8 1.7 1 0 0 1 1 1 0 Rit1 DUSP-like domain Presenilin PF01080.17 CDJ68985.1 - 0.66 8.7 9.6 2.3 6.9 8.3 1.9 2 0 0 2 2 2 0 Presenilin DUF4228 PF14009.6 CDJ68985.1 - 1.8 9.0 9.0 1.7 9.0 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) RskA PF10099.9 CDJ68985.1 - 5.8 7.2 59.0 0.041 14.2 15.2 3.5 1 1 2 3 3 3 0 Anti-sigma-K factor rskA WD40 PF00400.32 CDJ68987.1 - 1.1e-18 67.2 5.9 0.0067 17.3 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ68987.1 - 2.8e-09 37.1 0.0 0.15 12.3 0.0 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 CDJ68987.1 - 0.015 14.6 0.8 0.76 9.1 0.0 3.0 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 CDJ68987.1 - 0.019 14.2 0.0 0.019 14.2 0.0 3.7 4 1 1 5 5 5 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FAM176 PF14851.6 CDJ68987.1 - 0.19 11.4 0.6 0.37 10.4 0.6 1.4 1 0 0 1 1 1 0 FAM176 family SUIM_assoc PF16619.5 CDJ68987.1 - 1.2 9.2 26.2 1.1 9.4 2.0 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CDJ68988.1 - 0.34 11.5 9.5 0.39 11.3 9.5 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein eIF-3_zeta PF05091.12 CDJ68989.1 - 0.0092 15.0 5.8 0.0094 15.0 5.8 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BAF1_ABF1 PF04684.13 CDJ68989.1 - 0.015 14.4 9.9 0.017 14.2 9.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ68989.1 - 0.42 9.3 13.9 0.64 8.7 13.9 1.2 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 CDJ68989.1 - 0.48 10.0 12.1 0.67 9.5 12.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) AAA_23 PF13476.6 CDJ68989.1 - 0.55 10.7 10.6 0.95 9.9 10.6 1.4 1 1 0 1 1 1 0 AAA domain RskA PF10099.9 CDJ68989.1 - 2.7 8.3 36.9 11 6.3 36.9 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Band_3_cyto PF07565.13 CDJ68989.1 - 3.5 7.3 13.1 1.9 8.3 9.6 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF1980 PF09323.10 CDJ68989.1 - 3.7 7.4 7.0 8.2 6.3 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RNA_pol_Rpc4 PF05132.14 CDJ68989.1 - 6.5 7.2 16.6 7.7 6.9 8.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Coilin_N PF15862.5 CDJ68989.1 - 7.1 6.4 13.4 22 4.8 13.4 1.8 1 0 0 1 1 1 0 Coilin N-terminus XhlA PF10779.9 CDJ68990.1 - 0.0078 16.4 3.6 0.0094 16.1 0.5 2.6 2 0 0 2 2 2 1 Haemolysin XhlA Metal_resist PF13801.6 CDJ68990.1 - 0.064 13.4 12.8 0.1 12.8 0.1 3.7 3 0 0 3 3 3 0 Heavy-metal resistance Peptidase_M3 PF01432.20 CDJ68991.1 - 5.8e-12 45.6 1.1 7.2e-12 45.3 1.0 1.3 1 1 0 1 1 1 1 Peptidase family M3 DUF3198 PF11433.8 CDJ68991.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) SUIM_assoc PF16619.5 CDJ68992.1 - 0.0038 17.3 5.7 0.0038 17.3 5.7 5.6 3 2 1 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 DUF1611_N PF17396.2 CDJ68992.1 - 0.026 14.7 0.6 5.1 7.4 0.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain DUF4820 PF16091.5 CDJ68992.1 - 0.089 12.1 8.2 0.018 14.5 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) TBCC PF07986.12 CDJ68992.1 - 0.9 9.3 7.4 16 5.3 1.8 2.7 1 1 1 2 2 2 0 Tubulin binding cofactor C YliH PF10799.8 CDJ68993.1 - 0.12 12.3 2.1 0.66 9.9 0.1 3.3 2 0 0 2 2 2 0 Biofilm formation protein (YliH/bssR) RskA PF10099.9 CDJ68994.1 - 0.00046 20.5 9.6 0.00046 20.5 9.6 6.2 2 2 1 3 3 3 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ68994.1 - 0.011 15.4 20.6 0.011 15.4 20.6 4.0 3 1 0 3 3 3 0 Spt20 family mRNA_triPase PF02940.15 CDJ68994.1 - 0.028 14.1 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain Apt1 PF10351.9 CDJ68994.1 - 0.1 11.5 8.0 0.042 12.7 4.9 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain PH_4 PF15404.6 CDJ68994.1 - 0.1 12.4 2.8 0.3 10.8 2.8 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain eIF-3_zeta PF05091.12 CDJ68994.1 - 0.23 10.4 10.8 0.37 9.7 10.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S64 PF08192.11 CDJ68994.1 - 0.88 8.0 10.8 1.5 7.2 10.8 1.4 1 0 0 1 1 1 0 Peptidase family S64 THOC2_N PF16134.5 CDJ68994.1 - 2.4 6.7 12.1 4.9 5.7 8.8 2.5 1 1 1 2 2 2 0 THO complex subunit 2 N-terminus RskA PF10099.9 CDJ68995.1 - 5.3e-09 36.6 0.0 0.00014 22.2 0.0 2.1 1 1 1 2 2 2 2 Anti-sigma-K factor rskA ER_lumen_recept PF00810.18 CDJ68995.1 - 5.6e-07 30.5 0.1 1.4e-05 26.0 0.1 2.3 1 1 1 2 2 2 1 ER lumen protein retaining receptor Spt20 PF12090.8 CDJ68995.1 - 2.7e-05 23.9 48.4 3.8e-05 23.4 17.0 2.2 2 0 0 2 2 2 2 Spt20 family Presenilin PF01080.17 CDJ68995.1 - 2.8e-05 23.1 3.1 2.8e-05 23.1 3.1 2.2 2 0 0 2 2 2 1 Presenilin DUF1645 PF07816.11 CDJ68995.1 - 0.0025 18.4 24.8 0.021 15.4 18.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1645) DUF4834 PF16118.5 CDJ68995.1 - 0.009 17.0 2.5 0.009 17.0 2.5 3.2 1 1 1 2 2 1 1 Domain of unknown function (DUF4834) DUF755 PF05501.11 CDJ68995.1 - 0.01 16.1 37.4 0.01 16.1 37.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) PAP2_3 PF14378.6 CDJ68995.1 - 0.013 15.2 0.3 2 8.1 0.0 2.2 2 0 0 2 2 2 0 PAP2 superfamily SAGA-Tad1 PF12767.7 CDJ68995.1 - 0.019 14.7 14.8 0.015 15.0 5.5 2.0 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit TFIIA PF03153.13 CDJ68995.1 - 0.09 12.8 49.1 0.24 11.4 24.6 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CNDH2_M PF16869.5 CDJ68995.1 - 0.15 12.7 0.6 0.15 12.7 0.6 3.1 2 1 0 2 2 1 0 PF16858 Hid1 PF12722.7 CDJ68995.1 - 0.18 9.9 20.3 0.25 9.4 20.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM76 PF16046.5 CDJ68995.1 - 0.4 10.0 23.0 0.44 9.8 10.8 2.0 2 0 0 2 2 2 0 FAM76 protein Orf78 PF06024.12 CDJ68995.1 - 0.48 10.7 0.1 0.48 10.7 0.1 3.3 2 1 1 3 3 3 0 Orf78 (ac78) MPM1 PF17234.2 CDJ68995.1 - 0.51 10.6 26.4 2.2 8.5 14.1 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 PorA PF11271.8 CDJ68995.1 - 0.95 8.7 9.8 2 7.7 0.2 2.2 2 0 0 2 2 2 0 Porin PorA DUF4820 PF16091.5 CDJ68995.1 - 0.95 8.8 19.0 1.2 8.4 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) TOM20_plant PF06552.12 CDJ68995.1 - 1.2 8.8 7.5 3 7.6 2.6 2.1 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 DUF775 PF05603.12 CDJ68995.1 - 1.2 8.6 21.4 2.7 7.5 7.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Tir_receptor_N PF07490.11 CDJ68995.1 - 1.3 8.8 8.7 0.065 13.1 2.0 1.9 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus LAP1C PF05609.12 CDJ68995.1 - 1.6 7.7 23.4 2.4 7.2 23.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SPX PF03105.19 CDJ68995.1 - 2.6 7.9 26.6 5.2 6.9 26.6 1.4 1 1 0 1 1 1 0 SPX domain RAP1 PF07218.11 CDJ68995.1 - 3.3 5.9 12.3 4.2 5.5 12.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Miga PF10265.9 CDJ68995.1 - 3.4 6.5 22.5 0.035 13.1 13.0 1.9 2 0 0 2 2 2 0 Mitoguardin PPL5 PF18168.1 CDJ68995.1 - 3.6 6.8 10.5 1.5 8.1 2.6 2.1 2 0 0 2 2 2 0 Prim-pol family 5 DUF2149 PF09919.9 CDJ68995.1 - 4.5 7.6 9.5 6.4 7.1 4.4 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) DUF702 PF05142.12 CDJ68995.1 - 5.2 7.5 25.6 8.7 6.8 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) SSP160 PF06933.11 CDJ68995.1 - 5.8 5.0 13.8 7.7 4.6 13.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BORG_CEP PF14957.6 CDJ68995.1 - 5.9 8.1 22.0 5.1 8.3 13.0 2.1 2 0 0 2 2 2 0 Cdc42 effector FHIPEP PF00771.20 CDJ68995.1 - 7.1 5.0 14.0 2.2 6.6 2.8 2.1 1 1 1 2 2 2 0 FHIPEP family SKA1 PF07160.12 CDJ68995.1 - 8.4 6.2 23.3 0.45 10.3 10.5 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Dehydrin PF00257.19 CDJ68996.1 - 0.016 15.8 13.0 0.016 15.8 13.0 5.0 2 1 2 4 4 4 0 Dehydrin DUF3446 PF11928.8 CDJ68996.1 - 0.046 14.0 1.2 0.046 14.0 1.2 4.2 3 1 0 4 4 4 0 Early growth response N-terminal domain Hamartin PF04388.12 CDJ68996.1 - 7 5.2 46.8 11 4.5 46.8 1.3 1 0 0 1 1 1 0 Hamartin protein His_Phos_1 PF00300.22 CDJ68997.1 - 3e-38 131.5 0.0 1.8e-30 106.1 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) TAF6_C PF07571.13 CDJ68997.1 - 0.065 13.6 0.0 0.35 11.2 0.0 2.1 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Activator_LAG-3 PF11498.8 CDJ68998.1 - 0.024 13.6 16.0 0.031 13.3 16.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ68998.1 - 0.8 9.6 10.4 0.89 9.5 10.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_primase_lrg PF04104.14 CDJ68999.1 - 2e-29 102.8 0.0 2.2e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit STAT_int PF02865.17 CDJ68999.1 - 0.1 13.1 0.1 5.6 7.4 0.0 2.2 2 0 0 2 2 2 0 STAT protein, protein interaction domain RAB3GAP2_N PF14655.6 CDJ69000.1 - 0.058 12.7 1.9 0.065 12.5 1.9 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Roughex PF06020.11 CDJ69000.1 - 0.065 12.3 7.2 0.067 12.3 7.2 1.0 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ69000.1 - 0.077 12.6 15.0 0.086 12.4 15.0 1.0 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ69000.1 - 0.14 11.1 10.7 0.14 11.0 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 CDJ69000.1 - 0.52 10.3 6.5 0.63 10.1 6.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TFIIA PF03153.13 CDJ69000.1 - 0.54 10.2 14.9 0.55 10.2 14.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DLIC PF05783.11 CDJ69000.1 - 1.4 7.7 6.4 1.5 7.6 6.4 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Presenilin PF01080.17 CDJ69000.1 - 3.2 6.4 5.1 3.1 6.5 5.1 1.1 1 0 0 1 1 1 0 Presenilin Med15 PF09606.10 CDJ69000.1 - 4 6.0 18.4 4.1 6.0 18.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Shadoo PF14999.6 CDJ69000.1 - 6.8 6.8 18.8 8.5 6.5 18.8 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF4834 PF16118.5 CDJ69000.1 - 7 7.7 7.8 9 7.3 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PS_Dcarbxylase PF02666.15 CDJ69001.1 - 1.8e-22 79.9 0.1 2.4e-21 76.2 0.1 1.9 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase SUIM_assoc PF16619.5 CDJ69002.1 - 0.00052 20.0 2.2 0.00081 19.4 2.2 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ69002.1 - 0.065 12.8 4.2 0.08 12.6 4.2 1.1 1 0 0 1 1 1 0 Spt20 family YajC PF02699.15 CDJ69002.1 - 3.1 7.7 6.6 4.7 7.2 6.6 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit CDK2AP PF09806.9 CDJ69003.1 - 0.02 15.0 14.1 0.025 14.7 14.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein TAF4 PF05236.14 CDJ69003.1 - 0.13 12.0 15.0 0.16 11.7 15.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 CDJ69003.1 - 0.65 9.7 13.2 0.76 9.5 13.2 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit V_ATPase_I PF01496.19 CDJ69003.1 - 3.5 5.4 12.5 4 5.2 12.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ69003.1 - 4.3 6.0 16.8 5.2 5.7 16.8 1.0 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CDJ69003.1 - 5.6 6.2 22.1 6.9 5.9 22.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hydin_ADK PF17213.3 CDJ69003.1 - 5.8 7.2 11.7 6.6 7.0 11.7 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain FAM60A PF15396.6 CDJ69003.1 - 6 6.8 9.1 7.5 6.5 9.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A XRN_M PF17846.1 CDJ69003.1 - 6.1 5.7 11.8 6.6 5.6 11.8 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Zip PF02535.22 CDJ69003.1 - 7.7 5.6 6.5 8.7 5.5 6.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4484 PF14831.6 CDJ69003.1 - 8.5 6.4 12.8 11 6.0 12.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) AAA_23 PF13476.6 CDJ69003.1 - 9.4 6.7 21.6 13 6.2 21.6 1.1 1 0 0 1 1 1 0 AAA domain SNARE PF05739.19 CDJ69004.1 - 1e-06 28.6 0.6 4.1e-06 26.7 0.2 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CDJ69004.1 - 8.3e-06 25.6 2.9 8.3e-06 25.6 2.9 1.8 2 1 0 2 2 2 1 Syntaxin Syntaxin-6_N PF09177.11 CDJ69004.1 - 0.012 16.2 1.4 0.7 10.5 0.1 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal F_actin_bind PF08919.10 CDJ69004.1 - 0.014 15.4 1.0 0.043 13.9 0.2 2.0 2 0 0 2 2 2 0 F-actin binding HhH-GPD PF00730.25 CDJ69004.1 - 0.02 15.3 0.0 0.035 14.5 0.0 1.7 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DUF1664 PF07889.12 CDJ69004.1 - 0.027 14.5 1.3 5 7.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc29 PF17082.5 CDJ69004.1 - 0.044 13.6 3.2 0.083 12.7 0.7 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 Sod_Ni PF09055.11 CDJ69004.1 - 0.048 14.2 0.3 0.22 12.1 0.0 2.1 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase Rho_N PF07498.12 CDJ69004.1 - 0.048 13.6 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Turandot PF07240.11 CDJ69004.1 - 0.065 13.2 0.3 5 7.2 0.1 2.6 1 1 1 2 2 2 0 Stress-inducible humoral factor Turandot Vac_Fusion PF02346.16 CDJ69004.1 - 0.13 11.9 3.0 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF948 PF06103.11 CDJ69004.1 - 0.16 12.2 2.0 15 5.9 0.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_Mu_Gam PF07352.12 CDJ69004.1 - 0.63 9.9 3.8 7.5 6.4 0.1 2.3 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF148 PF02520.17 CDJ69004.1 - 2 8.6 8.7 1 9.5 1.1 3.3 1 1 0 3 3 3 0 Domain of unknown function DUF148 Apt1 PF10351.9 CDJ69005.1 - 0.045 12.6 6.4 0.044 12.7 6.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ69005.1 - 0.55 9.8 26.8 0.73 9.4 26.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tic110 PF16940.5 CDJ69005.1 - 2.8 6.3 7.7 3.5 6.0 7.7 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter NPR3 PF03666.13 CDJ69005.1 - 3.9 6.2 6.4 4.4 6.0 6.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ribosomal_60s PF00428.19 CDJ69005.1 - 4.3 8.0 19.0 6.6 7.4 19.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Dsh_C PF12316.8 CDJ69005.1 - 6.2 7.2 20.3 7.8 6.8 20.3 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal eIF-3_zeta PF05091.12 CDJ69006.1 - 0.13 11.2 10.4 0.056 12.4 1.3 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1943 PF09172.11 CDJ69006.1 - 0.18 11.0 0.1 0.18 11.0 0.1 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF1943) Spore_III_AF PF09581.10 CDJ69006.1 - 0.31 11.1 4.4 0.45 10.5 0.1 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) DUF2722 PF10846.8 CDJ69006.1 - 0.6 9.0 22.0 0.96 8.3 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF150 PF02576.17 CDJ69006.1 - 1.7 9.1 3.3 38 4.8 0.2 3.7 1 1 2 3 3 3 0 RimP N-terminal domain EPL1 PF10513.9 CDJ69006.1 - 2.4 8.5 10.4 1.9 8.9 3.3 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF4834 PF16118.5 CDJ69006.1 - 4.4 8.3 12.6 20 6.2 6.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) eIF_4EBP PF05456.11 CDJ69006.1 - 7 6.6 9.4 0.3 11.0 2.4 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) BCDHK_Adom3 PF10436.9 CDJ69007.1 - 4.8e-08 33.0 0.0 8.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase SR-25 PF10500.9 CDJ69007.1 - 0.00076 19.2 46.8 0.065 12.8 17.4 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ69007.1 - 0.025 14.5 12.0 0.033 14.1 12.0 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ69007.1 - 0.31 9.9 14.3 0.46 9.3 14.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pheromone PF08015.11 CDJ69007.1 - 4 8.6 21.7 1.8 9.7 6.4 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone Filament_head PF04732.14 CDJ69007.1 - 5.1 8.0 43.3 3.8 8.4 19.7 2.3 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region CCDC106 PF15794.5 CDJ69007.1 - 5.4 6.7 18.1 0.74 9.5 4.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 HATPase_c PF02518.26 CDJ69008.1 - 0.098 13.2 0.0 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SUIM_assoc PF16619.5 CDJ69008.1 - 0.3 11.2 23.2 0.11 12.6 6.0 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ69008.1 - 0.39 10.7 13.6 0.45 10.5 13.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lipase_3 PF01764.25 CDJ69009.1 - 3.7e-12 46.3 0.0 1.3e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CDJ69009.1 - 0.0034 17.0 0.1 0.008 15.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 CDJ69009.1 - 0.13 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_23 PF13476.6 CDJ69009.1 - 0.3 11.6 5.0 0.46 11.0 5.0 1.2 1 0 0 1 1 1 0 AAA domain SUIM_assoc PF16619.5 CDJ69010.1 - 0.016 15.3 18.6 0.24 11.5 9.9 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SAND PF01342.21 CDJ69010.1 - 0.13 12.0 2.1 0.48 10.2 0.6 2.2 2 0 0 2 2 2 0 SAND domain DUF4813 PF16072.5 CDJ69011.1 - 7.4 6.1 38.3 10 5.7 38.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) WD40 PF00400.32 CDJ69013.1 - 3.3e-09 37.2 4.7 0.012 16.4 0.0 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat TFIIA PF03153.13 CDJ69014.1 - 0.0011 19.1 26.5 0.0013 18.8 26.5 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF840 PF05801.11 CDJ69014.1 - 0.057 13.5 0.2 0.057 13.5 0.2 1.8 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) RskA PF10099.9 CDJ69014.1 - 2.3 8.5 16.3 0.45 10.8 7.5 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Macoilin PF09726.9 CDJ69014.1 - 5.2 5.5 16.4 7.5 5.0 16.4 1.2 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 CDJ69014.1 - 7.7 6.4 25.8 9.5 6.0 25.8 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DivIC PF04977.15 CDJ69014.1 - 7.8 6.3 14.1 5.6 6.8 5.2 2.4 2 0 0 2 2 2 0 Septum formation initiator ISP1_C PF18161.1 CDJ69015.1 - 3.9e-43 145.8 0.0 5e-43 145.5 0.0 1.1 1 0 0 1 1 1 1 ISP1 C-terminal ISP3_C PF18045.1 CDJ69015.1 - 1.9e-39 133.9 0.0 2.4e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 ISP3 C-terminal NopRA1 PF16201.5 CDJ69016.1 - 6.1e-07 29.2 0.5 2.3e-06 27.3 0.5 2.1 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 CDJ69016.1 - 0.055 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal Pox_Ag35 PF03286.14 CDJ69016.1 - 0.2 11.4 1.1 0.97 9.2 1.1 2.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HHH_8 PF14716.6 CDJ69017.1 - 0.042 14.2 0.0 0.71 10.3 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF3613 PF12266.8 CDJ69019.1 - 0.049 13.4 0.5 0.17 11.7 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Mannosyl_trans PF05007.13 CDJ69022.1 - 2e-34 119.6 36.4 1.5e-24 87.3 10.2 4.1 2 1 1 3 3 3 3 Mannosyltransferase (PIG-M) GT87 PF09594.10 CDJ69022.1 - 2.7e-06 27.3 3.7 2.7e-06 27.3 3.7 2.8 2 1 0 2 2 2 1 Glycosyltransferase family 87 Ammonium_transp PF00909.21 CDJ69022.1 - 0.045 12.5 4.8 0.35 9.5 0.5 2.3 2 0 0 2 2 2 0 Ammonium Transporter Family Myosin_head PF00063.21 CDJ69023.1 - 1.6e-24 86.2 0.0 4.9e-10 38.3 0.0 3.1 3 0 0 3 3 3 3 Myosin head (motor domain) BTB PF00651.31 CDJ69024.1 - 2.1e-05 24.7 0.0 4.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain FPL PF09758.9 CDJ69025.1 - 3.1e-51 173.3 1.0 5.7e-51 172.4 1.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein SWIB PF02201.18 CDJ69026.1 - 1.8e-22 79.0 0.1 2.8e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain TFIIA PF03153.13 CDJ69026.1 - 0.0018 18.4 11.9 0.0022 18.1 11.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ69026.1 - 0.0026 17.8 9.8 0.0026 17.8 9.8 3.0 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 DUF3043 PF11241.8 CDJ69026.1 - 0.46 10.5 3.4 0.8 9.7 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) EBP50_C PF09007.11 CDJ69026.1 - 0.53 11.3 0.1 0.53 11.3 0.1 3.1 3 1 0 3 3 3 0 EBP50, C-terminal Spt20 PF12090.8 CDJ69026.1 - 4.7 6.7 19.8 9.4 5.8 19.8 1.4 1 0 0 1 1 1 0 Spt20 family ubiquitin PF00240.23 CDJ69027.1 - 5.3e-12 45.3 0.0 1.3e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CDJ69027.1 - 1.7e-06 27.8 0.7 4.6e-06 26.4 0.2 2.1 2 0 0 2 2 2 1 UBA/TS-N domain HOIP-UBA PF16678.5 CDJ69027.1 - 0.0073 16.3 0.2 0.0073 16.3 0.2 2.5 3 0 0 3 3 3 1 HOIP UBA domain pair CUE PF02845.16 CDJ69027.1 - 0.016 14.9 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 0 CUE domain DUF3246 PF11596.8 CDJ69027.1 - 0.15 11.5 6.9 0.3 10.5 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Pox_A12 PF04651.13 CDJ69027.1 - 0.4 10.7 8.9 0.73 9.9 8.9 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein TFIIE-A_C PF11521.8 CDJ69027.1 - 4.1 7.8 14.6 0.061 13.6 5.9 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Chromo PF00385.24 CDJ69028.1 - 4.1e-05 23.4 0.2 9.1e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chlor_dismutase PF06778.12 CDJ69028.1 - 0.71 9.4 3.5 2 8.0 0.1 2.4 2 0 0 2 2 2 0 Chlorite dismutase TFIIS_M PF07500.14 CDJ69029.1 - 2.2e-08 34.6 0.0 5.2e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Uds1 PF15456.6 CDJ69030.1 - 0.0027 17.9 5.5 0.005 17.0 5.5 1.4 1 0 0 1 1 1 1 Up-regulated During Septation UPF0565 PF10561.9 CDJ69030.1 - 0.016 14.4 0.2 0.017 14.3 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 TFIIA PF03153.13 CDJ69030.1 - 0.068 13.2 8.9 0.076 13.0 8.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.10 CDJ69030.1 - 0.61 10.1 4.6 0.89 9.6 4.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Coprogen_oxidas PF01218.18 CDJ69032.1 - 8.5e-13 47.7 0.2 2.5e-12 46.1 0.2 1.6 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase SUIM_assoc PF16619.5 CDJ69032.1 - 0.012 15.6 6.7 0.022 14.8 6.7 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF853 PF05872.12 CDJ69032.1 - 0.03 12.9 0.5 0.032 12.8 0.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) LCCL PF03815.19 CDJ69032.1 - 0.058 13.5 0.0 2.7 8.1 0.0 2.1 2 0 0 2 2 2 0 LCCL domain Ilar_coat PF01787.16 CDJ69032.1 - 0.067 13.0 0.1 0.09 12.6 0.1 1.1 1 0 0 1 1 1 0 Ilarvirus coat protein Coprogen_oxidas PF01218.18 CDJ69033.1 - 9.9e-67 224.7 0.5 1.2e-64 217.9 0.2 2.4 2 1 0 2 2 2 2 Coproporphyrinogen III oxidase DUF4834 PF16118.5 CDJ69033.1 - 0.12 13.4 0.0 0.19 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ69033.1 - 5.8 6.5 14.7 11 5.6 14.7 1.3 1 0 0 1 1 1 0 Spt20 family Hamartin PF04388.12 CDJ69035.1 - 5.4 5.5 4.6 7.4 5.1 4.6 1.1 1 0 0 1 1 1 0 Hamartin protein Sin_N PF04801.13 CDJ69036.1 - 1.2 8.3 12.0 0.27 10.4 5.7 2.0 2 0 0 2 2 2 0 Sin-like protein conserved region DUF1645 PF07816.11 CDJ69036.1 - 5.2 7.6 11.4 0.045 14.3 2.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ69036.1 - 6.1 6.4 42.8 0.79 9.3 5.5 3.1 3 0 0 3 3 3 0 Spt20 family ANAPC_CDC26 PF10471.9 CDJ69036.1 - 7.7 7.4 36.7 12 6.8 6.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 MDMPI_N PF11716.8 CDJ69037.1 - 0.024 15.3 1.3 0.024 15.3 1.3 9.7 8 3 3 11 11 11 0 Mycothiol maleylpyruvate isomerase N-terminal domain LIN52 PF10044.9 CDJ69037.1 - 0.17 12.6 0.1 0.17 12.6 0.1 2.9 3 0 0 3 3 3 0 Retinal tissue protein Gag_p10 PF02337.17 CDJ69037.1 - 0.57 10.2 3.3 0.33 10.9 0.4 2.1 2 0 0 2 2 2 0 Retroviral GAG p10 protein IMS_C PF11799.8 CDJ69038.1 - 6.6e-05 23.6 0.0 0.00011 22.9 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 CDJ69038.1 - 0.0098 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family SUIM_assoc PF16619.5 CDJ69038.1 - 8.6 6.5 9.4 3 8.0 0.6 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ADH_zinc_N PF00107.26 CDJ69040.1 - 7.3e-20 71.3 0.2 1.5e-19 70.2 0.2 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CDJ69040.1 - 0.00015 21.3 0.0 0.002 17.6 0.0 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CDJ69040.1 - 0.009 15.3 1.3 0.017 14.4 1.1 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 CDJ69040.1 - 0.02 15.9 0.0 0.033 15.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PCI PF01399.27 CDJ69041.1 - 0.076 13.5 0.0 0.73 10.4 0.0 2.1 2 0 0 2 2 2 0 PCI domain DUF3138 PF11336.8 CDJ69041.1 - 0.28 9.7 1.2 0.35 9.4 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) IN_DBD_C PF00552.21 CDJ69042.1 - 0.031 13.6 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Integrase DNA binding domain Exo_endo_phos PF03372.23 CDJ69043.1 - 1.3e-11 44.5 0.0 3.4e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4667 PF15700.5 CDJ69044.1 - 0.01 16.0 0.8 0.01 16.0 0.8 2.5 2 1 0 2 2 1 0 Domain of unknown function (DUF4667) SID-1_RNA_chan PF13965.6 CDJ69044.1 - 0.078 11.4 0.3 0.11 10.9 0.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1645 PF07816.11 CDJ69044.1 - 0.24 12.0 16.8 0.18 12.4 2.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) MMU163 PF17119.5 CDJ69044.1 - 1.4 8.0 11.8 0.51 9.5 2.0 3.0 3 0 0 3 3 3 0 Mitochondrial protein up-regulated during meiosis TCP PF03634.13 CDJ69044.1 - 3.2 8.3 23.9 0.64 10.6 12.2 3.2 3 0 0 3 3 3 0 TCP family transcription factor Membralin PF09746.9 CDJ69044.1 - 3.7 6.5 10.2 0.46 9.5 5.6 1.7 2 0 0 2 2 2 0 Tumour-associated protein DUF1980 PF09323.10 CDJ69044.1 - 4.3 7.2 8.6 0.5 10.2 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Peptidase_U57 PF05582.12 CDJ69044.1 - 6.1 6.0 8.3 13 5.0 8.3 1.4 1 0 0 1 1 1 0 YabG peptidase U57 Gti1_Pac2 PF09729.9 CDJ69044.1 - 6.4 6.8 16.2 14 5.8 11.4 2.6 3 0 0 3 3 3 0 Gti1/Pac2 family Rtf2 PF04641.12 CDJ69044.1 - 6.5 6.0 14.3 0.3 10.4 6.5 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger PIP5K PF01504.18 CDJ69044.1 - 6.5 5.9 14.2 2.4 7.3 10.8 1.9 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF3408 PF11888.8 CDJ69044.1 - 9.7 6.3 16.3 31 4.7 16.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SR-25 PF10500.9 CDJ69045.1 - 8.6e-05 22.3 2.6 8.6e-05 22.3 2.6 7.5 7 2 0 7 7 7 3 Nuclear RNA-splicing-associated protein Galactosyl_T PF01762.21 CDJ69046.1 - 1.3e-31 109.9 0.0 2e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase RskA PF10099.9 CDJ69046.1 - 0.0057 17.0 4.4 0.0057 17.0 4.4 6.1 1 1 2 3 3 3 1 Anti-sigma-K factor rskA GRP PF07172.11 CDJ69046.1 - 0.22 12.2 0.0 0.77 10.5 0.0 1.9 1 0 0 1 1 1 0 Glycine rich protein family Utp14 PF04615.13 CDJ69046.1 - 0.73 8.3 7.3 1.2 7.7 7.3 1.3 1 0 0 1 1 1 0 Utp14 protein Tme5_EGF_like PF09064.10 CDJ69048.1 - 0.016 15.1 4.0 9.6 6.2 0.6 5.6 6 0 0 6 6 6 0 Thrombomodulin like fifth domain, EGF-like CBM_14 PF01607.24 CDJ69048.1 - 2 8.6 0.0 2 8.6 0.0 6.1 5 2 1 6 6 6 0 Chitin binding Peritrophin-A domain SpoIIE PF07228.12 CDJ69049.1 - 1.8e-07 31.2 0.4 7.3e-07 29.3 0.4 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CDJ69049.1 - 9e-07 28.8 0.0 0.0047 16.6 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ69049.1 - 0.00081 19.1 2.2 0.0034 17.0 2.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Rep_fac-A_C PF08646.10 CDJ69050.1 - 2.8e-25 88.8 0.0 5.3e-20 71.7 0.0 3.0 2 1 1 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CDJ69050.1 - 3.9e-23 81.2 0.0 2.3e-21 75.5 0.1 2.9 3 0 0 3 3 3 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 CDJ69050.1 - 2.1e-13 50.1 0.1 5.9e-10 39.0 0.0 3.2 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CDJ69050.1 - 6.3e-05 22.8 0.1 0.00049 19.9 0.2 2.1 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 DUF4503 PF14951.6 CDJ69050.1 - 9.1e-05 21.1 0.3 9.1e-05 21.1 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4503) POT1 PF02765.17 CDJ69050.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 Zn_Tnp_IS1595 PF12760.7 CDJ69050.1 - 0.18 11.8 1.6 0.41 10.7 1.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Prominin PF05478.11 CDJ69051.1 - 5.4 4.8 9.1 0.76 7.7 4.2 1.8 2 0 0 2 2 2 0 Prominin REC114-like PF15165.6 CDJ69052.1 - 0.067 13.0 0.3 0.067 13.0 0.3 4.6 4 1 2 6 6 6 0 Meiotic recombination protein REC114-like TFIIA PF03153.13 CDJ69053.1 - 0.0018 18.4 23.3 0.0021 18.2 23.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ69053.1 - 0.003 16.4 15.3 0.0037 16.1 15.3 1.1 1 0 0 1 1 1 1 Presenilin DUF1800 PF08811.11 CDJ69053.1 - 0.019 14.0 4.9 0.02 13.9 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Suf PF05843.14 CDJ69053.1 - 0.034 14.1 11.8 0.04 13.9 11.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.10 CDJ69053.1 - 0.04 12.6 23.6 0.044 12.5 23.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CLN3 PF02487.17 CDJ69053.1 - 0.04 13.0 2.8 0.043 12.9 2.8 1.2 1 0 0 1 1 1 0 CLN3 protein BAAT_C PF08840.11 CDJ69053.1 - 0.07 13.0 3.6 0.093 12.6 3.6 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LAP1C PF05609.12 CDJ69053.1 - 0.085 11.9 17.9 0.099 11.7 17.9 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) eIF-3_zeta PF05091.12 CDJ69053.1 - 0.11 11.5 14.0 0.11 11.4 14.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hamartin PF04388.12 CDJ69053.1 - 0.16 10.6 19.1 0.21 10.2 19.1 1.1 1 0 0 1 1 1 0 Hamartin protein RR_TM4-6 PF06459.12 CDJ69053.1 - 0.2 11.5 12.2 0.22 11.3 12.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TMEM237 PF15383.6 CDJ69053.1 - 0.2 10.7 4.1 0.25 10.4 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 DUF2126 PF09899.9 CDJ69053.1 - 0.22 9.5 3.3 0.23 9.5 3.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PAT1 PF09770.9 CDJ69053.1 - 0.23 9.7 16.6 0.24 9.6 16.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF5426 PF17473.2 CDJ69053.1 - 0.36 11.1 3.9 0.51 10.6 3.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5426) SprA-related PF12118.8 CDJ69053.1 - 0.39 9.8 34.0 0.49 9.5 34.0 1.1 1 0 0 1 1 1 0 SprA-related family Cellulose_synt PF03552.14 CDJ69053.1 - 0.43 9.0 9.9 0.53 8.7 9.9 1.1 1 0 0 1 1 1 0 Cellulose synthase Pkinase_fungal PF17667.1 CDJ69053.1 - 0.46 9.2 10.4 0.58 8.9 10.4 1.2 1 0 0 1 1 1 0 Fungal protein kinase CSG2 PF16965.5 CDJ69053.1 - 0.6 9.0 4.2 0.73 8.7 4.2 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator PA26 PF04636.13 CDJ69053.1 - 0.65 8.8 10.3 0.72 8.7 10.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CrgA PF06781.12 CDJ69053.1 - 0.75 9.9 2.3 1.6 8.8 2.3 1.5 1 0 0 1 1 1 0 Cell division protein CrgA RMI1_N PF08585.12 CDJ69053.1 - 0.84 9.4 15.3 0.86 9.3 14.5 1.5 1 1 0 1 1 1 0 RecQ mediated genome instability protein DUF4457 PF14652.6 CDJ69053.1 - 0.87 8.8 8.9 1.1 8.4 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) SpoIIP PF07454.11 CDJ69053.1 - 1.2 8.5 10.8 1.5 8.2 10.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Glt_symporter PF03616.14 CDJ69053.1 - 1.3 7.7 2.7 1.6 7.3 2.7 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter MscS_TM PF12794.7 CDJ69053.1 - 1.6 7.5 5.6 1.8 7.3 5.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 FHIPEP PF00771.20 CDJ69053.1 - 1.7 7.0 6.2 2.1 6.7 6.2 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4407 PF14362.6 CDJ69053.1 - 1.8 7.9 11.6 2 7.7 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Folate_carrier PF01770.18 CDJ69053.1 - 2.7 6.6 6.7 3.2 6.4 6.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier V_ATPase_I PF01496.19 CDJ69053.1 - 3.3 5.5 11.4 4 5.2 11.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S64 PF08192.11 CDJ69053.1 - 3.5 6.0 17.5 4.5 5.6 17.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 SLC12 PF03522.15 CDJ69053.1 - 3.6 6.5 14.2 4.1 6.3 14.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Orf78 PF06024.12 CDJ69053.1 - 3.9 7.8 10.1 12 6.3 10.2 1.8 1 1 0 1 1 1 0 Orf78 (ac78) GREB1 PF15782.5 CDJ69053.1 - 4 4.4 26.3 5 4.1 26.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sec62 PF03839.16 CDJ69053.1 - 4.3 6.8 9.1 5.5 6.4 9.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 CDJ69053.1 - 4.7 6.3 10.8 5.5 6.1 10.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SR-25 PF10500.9 CDJ69053.1 - 5.8 6.5 52.7 0.65 9.6 25.7 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF5427 PF10310.9 CDJ69053.1 - 6 5.7 17.2 6.9 5.5 17.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PPP4R2 PF09184.11 CDJ69053.1 - 6.7 6.2 15.6 8.8 5.8 15.6 1.1 1 0 0 1 1 1 0 PPP4R2 DUF4366 PF14283.6 CDJ69053.1 - 7.2 6.6 9.3 13 5.8 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) LMBR1 PF04791.16 CDJ69053.1 - 7.3 5.4 5.9 7.1 5.4 5.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Transposase_21 PF02992.14 CDJ69053.1 - 7.9 5.7 6.6 11 5.1 6.6 1.3 1 0 0 1 1 1 0 Transposase family tnp2 HCO3_cotransp PF00955.21 CDJ69053.1 - 8.1 5.1 7.1 9.7 4.9 7.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family SBE2 PF17076.5 CDJ69053.1 - 9 4.4 16.1 12 4.0 16.1 1.2 1 0 0 1 1 1 0 SBE2, cell-wall formation Peroxin-13_N PF04088.13 CDJ69053.1 - 9.2 6.5 9.4 16 5.7 9.4 1.6 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Joubert PF15392.6 CDJ69053.1 - 9.9 5.8 23.2 12 5.5 23.2 1.0 1 0 0 1 1 1 0 Joubert syndrome-associated zf-C6H2 PF15801.5 CDJ69054.1 - 4.6e-12 46.0 8.3 7.2e-12 45.4 8.3 1.3 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding SUIM_assoc PF16619.5 CDJ69054.1 - 0.0035 17.4 3.0 0.0035 17.4 3.0 2.2 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 zf-MYND PF01753.18 CDJ69054.1 - 0.0049 16.9 9.4 0.0082 16.2 9.4 1.4 1 0 0 1 1 1 1 MYND finger TFIIA PF03153.13 CDJ69054.1 - 1.1 9.2 31.6 0.24 11.4 22.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ecl1 PF12855.7 CDJ69054.1 - 1.3 10.2 37.3 1.4 10.1 26.4 2.5 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Apt1 PF10351.9 CDJ69054.1 - 3.8 6.2 22.2 0.058 12.2 11.1 2.5 3 0 0 3 3 3 0 Golgi-body localisation protein domain WD40 PF00400.32 CDJ69055.1 - 5.1e-12 46.1 13.4 0.00064 20.5 0.0 7.2 6 1 0 6 6 6 4 WD domain, G-beta repeat DUF2722 PF10846.8 CDJ69055.1 - 0.0047 15.9 8.1 0.0047 15.9 8.1 6.2 6 0 0 6 6 6 4 Protein of unknown function (DUF2722) Peroxin-3 PF04882.12 CDJ69055.1 - 0.56 9.1 0.0 0.56 9.1 0.0 4.4 3 2 0 3 3 3 0 Peroxin-3 TFIIA PF03153.13 CDJ69056.1 - 0.00086 19.4 28.6 0.00086 19.4 28.6 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ69056.1 - 0.022 15.4 23.9 0.022 15.4 23.9 4.5 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Caldesmon PF02029.15 CDJ69056.1 - 3 6.5 43.4 4 6.1 43.4 1.1 1 0 0 1 1 1 0 Caldesmon Ras PF00071.22 CDJ69057.1 - 1.5e-32 112.4 0.1 1.7e-32 112.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ69057.1 - 9.9e-25 87.1 0.0 1.1e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ69057.1 - 5.6e-08 32.4 0.0 6.2e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ69057.1 - 2.8e-05 24.2 0.0 3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ69057.1 - 0.017 14.7 0.0 0.24 10.9 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DAP3 PF10236.9 CDJ69057.1 - 0.029 13.5 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 CDJ69057.1 - 0.05 13.9 0.0 0.05 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDJ69057.1 - 0.086 12.5 0.0 0.097 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ69057.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ69057.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Gtr1_RagA PF04670.12 CDJ69057.1 - 0.16 11.3 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 CDJ69057.1 - 0.21 11.1 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region LapA_dom PF06305.11 CDJ69059.1 - 0.0087 15.9 0.1 0.029 14.2 0.1 1.9 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain TFIIA PF03153.13 CDJ69060.1 - 0.00019 21.5 18.1 0.00022 21.4 18.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ69060.1 - 0.07 12.7 28.3 0.094 12.3 28.3 1.1 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ69060.1 - 0.085 11.9 8.2 0.1 11.7 8.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 CDJ69060.1 - 0.09 11.5 9.6 0.099 11.4 9.6 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDJ69060.1 - 0.2 10.4 9.1 0.22 10.3 9.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 CDJ69060.1 - 0.3 9.3 6.2 0.35 9.1 6.2 1.0 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 CDJ69060.1 - 0.38 9.5 8.3 0.5 9.1 8.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter EPL1 PF10513.9 CDJ69060.1 - 0.42 11.0 7.1 0.58 10.5 7.1 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF3801 PF12687.7 CDJ69060.1 - 0.57 10.2 11.9 0.87 9.6 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) SRP-alpha_N PF04086.13 CDJ69060.1 - 0.74 9.7 10.7 0.87 9.5 10.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NST1 PF13945.6 CDJ69060.1 - 0.86 9.7 14.5 1.2 9.2 14.5 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Ndc1_Nup PF09531.10 CDJ69060.1 - 0.97 8.0 10.3 1.1 7.8 10.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 CDJ69060.1 - 1.1 7.4 12.2 1.2 7.3 12.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.9 CDJ69060.1 - 1.5 7.2 10.7 1.8 7.0 10.7 1.2 1 0 0 1 1 1 0 Macoilin family SLC12 PF03522.15 CDJ69060.1 - 1.6 7.7 8.4 2 7.4 8.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF853 PF05872.12 CDJ69060.1 - 1.7 7.2 5.8 2.1 6.9 5.8 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) eIF-3_zeta PF05091.12 CDJ69060.1 - 1.8 7.5 11.9 2.1 7.3 11.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ69060.1 - 3 7.8 9.2 4 7.4 9.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TERB2 PF15101.6 CDJ69060.1 - 4.1 7.4 11.1 5.1 7.1 11.1 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4551 PF15087.6 CDJ69060.1 - 4.5 6.0 10.4 5.7 5.7 10.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GREB1 PF15782.5 CDJ69060.1 - 5.4 4.0 13.0 6 3.9 13.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RAP1 PF07218.11 CDJ69060.1 - 6.8 4.8 11.1 7.9 4.6 11.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CCDC106 PF15794.5 CDJ69060.1 - 9.1 5.9 16.7 12 5.5 16.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Paf1 PF03985.13 CDJ69060.1 - 9.5 5.1 11.7 12 4.8 11.7 1.1 1 0 0 1 1 1 0 Paf1 GEMIN8 PF15348.6 CDJ69061.1 - 0.0011 19.3 3.4 0.0011 19.3 3.4 7.7 6 4 0 7 7 7 2 Gemini of Cajal bodies-associated protein 8 TFIIA PF03153.13 CDJ69061.1 - 0.0037 17.3 14.2 0.0037 17.3 14.2 9.1 4 2 3 8 8 8 2 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ69062.1 - 1.1 8.2 6.8 2 7.4 6.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein RimM PF01782.18 CDJ69063.1 - 3.8e-10 39.8 0.0 3.8e-10 39.8 0.0 2.3 3 0 0 3 3 3 1 RimM N-terminal domain zf-C2H2_8 PF15909.5 CDJ69063.1 - 0.023 15.0 1.0 1.5 9.2 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc ribbon CemA PF03040.14 CDJ69063.1 - 1.5 8.7 4.5 3.8 7.4 4.5 1.6 1 0 0 1 1 1 0 CemA family Pkinase_fungal PF17667.1 CDJ69063.1 - 2.5 6.8 8.5 3.4 6.3 0.9 3.1 3 0 0 3 3 3 0 Fungal protein kinase RskA PF10099.9 CDJ69064.1 - 0.00038 20.8 26.7 0.022 15.0 20.2 2.2 2 0 0 2 2 2 2 Anti-sigma-K factor rskA Amidohydro_2 PF04909.14 CDJ69064.1 - 0.0082 16.0 0.3 0.05 13.4 0.0 1.9 1 1 0 2 2 2 1 Amidohydrolase Spo7_2_N PF15407.6 CDJ69064.1 - 0.038 13.6 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 Ribosomal_60s PF00428.19 CDJ69064.1 - 0.052 14.1 4.9 0.052 14.1 4.9 2.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein Dmrt1 PF12374.8 CDJ69064.1 - 0.054 13.9 11.7 1.1 9.7 4.0 2.4 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Shadoo PF14999.6 CDJ69064.1 - 0.21 11.7 20.8 0.31 11.1 8.2 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective TFIIA PF03153.13 CDJ69064.1 - 0.29 11.1 16.2 0.34 10.8 16.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ69064.1 - 2 8.0 14.6 0.74 9.4 12.5 1.5 2 0 0 2 2 2 0 Spt20 family Hc1 PF07432.13 CDJ69064.1 - 3.7 8.0 21.5 1.4 9.3 10.5 2.1 2 0 0 2 2 2 0 Histone H1-like protein Hc1 DUF2849 PF11011.8 CDJ69064.1 - 8.5 7.1 11.6 1.3 9.7 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) PWI PF01480.17 CDJ69065.1 - 1.4e-13 50.9 2.1 2.1e-13 50.4 0.3 2.0 2 0 0 2 2 2 1 PWI domain SPX PF03105.19 CDJ69065.1 - 0.00012 22.1 14.9 0.00013 22.0 14.9 1.2 1 0 0 1 1 1 1 SPX domain RAP1 PF07218.11 CDJ69065.1 - 0.00018 20.0 9.5 0.0002 19.8 9.5 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 CDJ69065.1 - 0.011 14.4 19.5 0.013 14.1 19.5 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 CDJ69065.1 - 0.34 9.6 12.3 0.38 9.4 12.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.15 CDJ69065.1 - 0.45 10.0 19.6 0.71 9.4 19.6 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 CDJ69065.1 - 1.1 6.3 20.0 1.3 6.1 20.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5401 PF17380.2 CDJ69065.1 - 2 6.4 20.0 0.2 9.7 15.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5401) SLC12 PF03522.15 CDJ69065.1 - 2.6 7.0 17.1 3.7 6.5 17.1 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Menin PF05053.13 CDJ69065.1 - 8 4.7 15.1 10 4.3 15.1 1.2 1 0 0 1 1 1 0 Menin SR-25 PF10500.9 CDJ69066.1 - 0.012 15.2 1.0 0.012 15.2 1.0 7.5 4 2 2 7 7 7 0 Nuclear RNA-splicing-associated protein AAA_5 PF07728.14 CDJ69066.1 - 0.053 13.5 0.4 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mit_KHE1 PF10173.9 CDJ69066.1 - 0.19 11.8 5.5 6 6.9 0.0 3.7 3 0 0 3 3 3 0 Mitochondrial K+-H+ exchange-related AAA PF00004.29 CDJ69066.1 - 0.82 10.1 3.1 1.8 9.0 0.1 3.1 3 1 1 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 CDJ69066.1 - 8.2 6.8 9.5 0.46 10.8 2.1 2.8 2 0 0 2 2 2 0 AAA C-terminal domain MecA PF05389.12 CDJ69066.1 - 8.4 5.9 13.5 19 4.8 3.4 3.5 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) LRR_4 PF12799.7 CDJ69067.1 - 9.7e-10 38.6 1.0 9.7e-07 29.0 0.2 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ69067.1 - 0.00016 21.4 3.3 0.0027 17.4 3.5 2.2 1 1 1 2 2 2 2 Leucine rich repeat SPOUT_MTase PF02590.17 CDJ69067.1 - 0.00028 20.9 3.9 0.00075 19.5 3.9 1.7 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase LRR_9 PF14580.6 CDJ69067.1 - 0.012 15.1 0.0 0.012 15.1 0.0 1.6 2 0 0 2 2 2 0 Leucine-rich repeat Eno-Rase_NADH_b PF12242.8 CDJ69067.1 - 0.058 13.1 0.4 0.058 13.1 0.4 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LRR_1 PF00560.33 CDJ69067.1 - 0.095 13.3 2.7 29 5.7 0.4 3.5 2 1 0 2 2 2 0 Leucine Rich Repeat SARAF PF06682.12 CDJ69067.1 - 0.36 10.4 21.7 1 9.0 21.7 1.6 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis RAP1 PF07218.11 CDJ69067.1 - 5.8 5.1 18.7 9.9 4.3 18.7 1.5 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) OATP PF03137.20 CDJ69067.1 - 6.3 5.0 10.2 12 4.1 10.3 1.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family rRNA_proc-arch PF13234.6 CDJ69068.1 - 1.4e-48 166.2 0.0 2.4e-48 165.4 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 CDJ69068.1 - 5.2e-08 33.2 0.1 1.6e-06 28.4 0.0 2.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Tryp_alpha_amyl PF00234.22 CDJ69068.1 - 2.7 8.5 8.9 0.82 10.1 4.1 2.5 2 0 0 2 2 2 0 Protease inhibitor/seed storage/LTP family DUF4647 PF15504.6 CDJ69069.1 - 0.00033 19.9 11.6 0.00043 19.5 11.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4647) TPR_14 PF13428.6 CDJ69069.1 - 0.00051 20.6 9.8 0.0064 17.2 5.8 5.1 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ69069.1 - 0.00051 20.0 0.1 0.023 14.9 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ69069.1 - 0.0019 18.2 14.4 0.005 16.9 1.6 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat SR-25 PF10500.9 CDJ69069.1 - 0.0022 17.7 14.4 0.0031 17.2 14.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TPR_9 PF13371.6 CDJ69069.1 - 0.0049 17.0 3.7 0.0049 17.0 3.7 3.7 4 2 0 4 4 3 1 Tetratricopeptide repeat Presenilin PF01080.17 CDJ69069.1 - 0.01 14.6 9.2 0.012 14.5 9.2 1.2 1 0 0 1 1 1 0 Presenilin TPR_16 PF13432.6 CDJ69069.1 - 0.011 16.4 24.8 0.044 14.4 20.2 4.7 3 2 1 4 4 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ69069.1 - 0.028 14.2 4.4 0.46 10.4 0.3 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ69069.1 - 0.1 13.0 0.0 0.1 13.0 0.0 3.1 3 1 0 3 3 2 0 Tetratricopeptide repeat Ndc1_Nup PF09531.10 CDJ69069.1 - 0.11 11.2 12.8 0.12 11.1 12.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Med15 PF09606.10 CDJ69069.1 - 0.34 9.6 31.4 0.4 9.3 31.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MMR1 PF08505.10 CDJ69069.1 - 0.37 11.1 18.8 0.51 10.6 18.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SRP-alpha_N PF04086.13 CDJ69069.1 - 0.4 10.6 13.5 0.52 10.2 13.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CCDC106 PF15794.5 CDJ69069.1 - 0.52 10.0 14.6 0.79 9.4 14.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF5349 PF17298.2 CDJ69069.1 - 1.3 8.7 23.2 2.8 7.6 23.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5349) Apt1 PF10351.9 CDJ69069.1 - 1.9 7.2 12.3 2.5 6.9 12.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM60A PF15396.6 CDJ69069.1 - 2.1 8.3 8.2 3.1 7.7 8.2 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF966 PF06136.13 CDJ69069.1 - 3.9 7.1 17.7 5.3 6.7 17.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PNISR PF15996.5 CDJ69069.1 - 3.9 7.7 20.9 6.3 7.0 20.9 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR 2HCT PF03390.15 CDJ69069.1 - 4.5 5.8 5.2 0.65 8.6 0.9 1.7 2 0 0 2 2 2 0 2-hydroxycarboxylate transporter family Peptidase_S64 PF08192.11 CDJ69069.1 - 5.4 5.4 15.4 6.6 5.1 15.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Hamartin PF04388.12 CDJ69069.1 - 6 5.4 13.4 7.3 5.1 13.4 1.1 1 0 0 1 1 1 0 Hamartin protein DUF755 PF05501.11 CDJ69069.1 - 8.2 6.7 29.8 0.37 11.1 18.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF2464 PF10240.9 CDJ69069.1 - 9.4 5.7 9.7 14 5.2 9.7 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 SID-1_RNA_chan PF13965.6 CDJ69070.1 - 0.06 11.7 8.3 0.076 11.4 8.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 O-antigen_lig PF13425.6 CDJ69070.1 - 0.061 12.1 7.2 0.081 11.7 7.2 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PAT1 PF09770.9 CDJ69070.1 - 0.13 10.5 39.1 0.13 10.5 39.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ69070.1 - 0.36 10.6 30.6 0.46 10.3 30.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ69070.1 - 0.74 8.8 28.1 0.88 8.5 28.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4045 PF13254.6 CDJ69070.1 - 1.2 8.7 29.6 1.4 8.4 29.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CCDC106 PF15794.5 CDJ69070.1 - 1.8 8.2 26.3 3.1 7.5 26.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF572 PF04502.13 CDJ69070.1 - 2.3 7.8 26.5 3.2 7.3 26.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) SAGA-Tad1 PF12767.7 CDJ69070.1 - 3.6 7.3 24.6 4.2 7.0 24.6 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit ALMT PF11744.8 CDJ69070.1 - 4.6 6.0 21.9 5.1 5.8 21.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hamartin PF04388.12 CDJ69070.1 - 6.8 5.2 23.3 7 5.2 23.3 1.1 1 0 0 1 1 1 0 Hamartin protein GREB1 PF15782.5 CDJ69070.1 - 7.3 3.6 26.7 7.4 3.5 26.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CDJ69071.1 - 0.0022 18.1 24.5 0.0022 18.1 24.5 6.0 2 1 2 5 5 5 2 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 CDJ69071.1 - 0.026 14.1 0.3 0.026 14.1 0.3 5.1 4 1 1 5 5 5 0 Family of unknown function (DUF572) SPX PF03105.19 CDJ69071.1 - 3.1 7.6 73.4 0.23 11.3 0.1 5.4 3 2 2 5 5 5 0 SPX domain RrnaAD PF00398.20 CDJ69072.1 - 1e-17 64.1 0.1 1.3e-17 63.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Robl_LC7 PF03259.17 CDJ69072.1 - 0.0067 16.2 0.2 0.013 15.3 0.2 1.5 1 0 0 1 1 1 1 Roadblock/LC7 domain SR-25 PF10500.9 CDJ69073.1 - 0.019 14.6 34.3 0.025 14.2 33.0 1.6 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein TAF1D PF15333.6 CDJ69073.1 - 0.18 11.5 19.3 0.25 11.0 19.3 1.2 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D RR_TM4-6 PF06459.12 CDJ69073.1 - 0.28 11.0 17.0 0.3 10.9 17.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOBP PF15279.6 CDJ69073.1 - 0.39 11.3 21.7 0.44 11.1 21.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PA26 PF04636.13 CDJ69073.1 - 0.67 8.8 11.3 0.59 9.0 11.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Serinc PF03348.15 CDJ69073.1 - 1.3 7.9 9.4 1.5 7.6 9.4 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.16 CDJ69073.1 - 2.4 8.2 12.8 3 7.9 12.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 CDJ69073.1 - 3.5 6.5 22.4 4.1 6.3 22.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RAP1 PF07218.11 CDJ69073.1 - 5 5.3 6.8 4.7 5.4 6.8 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GREB1 PF15782.5 CDJ69073.1 - 5.2 4.1 23.3 5 4.1 23.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ69073.1 - 6.3 4.9 29.9 7.8 4.6 29.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TCP PF03634.13 CDJ69073.1 - 6.6 7.3 30.2 0.91 10.1 26.4 1.5 2 0 0 2 2 2 0 TCP family transcription factor XRCC4 PF06632.12 CDJ69073.1 - 7.6 5.3 21.8 9.8 4.9 21.8 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RIFIN PF02009.16 CDJ69073.1 - 8.2 6.2 18.0 12 5.7 18.0 1.3 1 0 0 1 1 1 0 Rifin SR-25 PF10500.9 CDJ69074.1 - 0.17 11.5 12.5 0.19 11.3 12.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Adaptin_N PF01602.20 CDJ69075.1 - 6.4e-47 160.3 16.6 1.7e-45 155.6 0.8 4.3 3 1 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 CDJ69075.1 - 0.069 13.2 7.1 0.16 12.0 0.0 3.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDJ69075.1 - 0.17 12.2 6.1 7.5 7.1 0.3 4.6 3 0 0 3 3 3 0 HEAT repeat DUF2973 PF11189.8 CDJ69075.1 - 6.5 6.9 0.0 6.5 6.9 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2973) DUF2722 PF10846.8 CDJ69076.1 - 0.0004 19.5 19.2 0.021 13.8 10.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Scs3p PF10261.9 CDJ69076.1 - 0.55 9.7 2.6 0.48 9.9 0.6 1.8 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM RPA43_OB PF17875.1 CDJ69076.1 - 0.59 10.8 3.6 36 5.0 0.0 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I EPL1 PF10513.9 CDJ69076.1 - 0.99 9.8 6.6 6.3 7.2 3.3 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like SpoIIP PF07454.11 CDJ69076.1 - 1.3 8.4 5.7 0.49 9.8 1.2 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Trp_oprn_chp PF09534.10 CDJ69078.1 - 3.2e-05 23.8 29.2 0.00019 21.3 23.8 2.2 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CcmF_C PF16327.5 CDJ69078.1 - 0.011 15.1 4.1 0.015 14.6 4.1 1.2 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal HAGH_C PF16123.5 CDJ69078.1 - 0.025 15.1 4.2 0.038 14.5 1.9 2.3 2 0 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus FA_desaturase PF00487.24 CDJ69078.1 - 0.085 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase YukD PF08817.10 CDJ69078.1 - 0.65 10.7 3.0 1.6 9.4 0.1 2.3 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD DUF4770 PF15994.5 CDJ69078.1 - 0.67 10.2 11.4 1 9.5 6.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Dehydrin PF00257.19 CDJ69078.1 - 0.72 10.4 18.1 1.3 9.6 13.5 2.3 2 1 0 2 2 2 0 Dehydrin DUF2298 PF10060.9 CDJ69078.1 - 0.98 8.1 11.2 0.27 9.9 8.4 1.6 2 0 0 2 2 2 0 Uncharacterized membrane protein (DUF2298) LUC7 PF03194.15 CDJ69078.1 - 3.5 7.2 13.9 0.076 12.7 7.0 1.7 2 0 0 2 2 2 0 LUC7 N_terminus EPL1 PF10513.9 CDJ69078.1 - 7 7.0 7.7 42 4.5 5.5 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like 4HBT PF03061.22 CDJ69079.1 - 0.0011 19.3 0.1 0.0011 19.3 0.1 2.2 3 0 0 3 3 3 1 Thioesterase superfamily NifQ PF04891.12 CDJ69079.1 - 0.052 13.9 0.7 0.35 11.2 0.1 2.2 2 0 0 2 2 2 0 NifQ TFIIA PF03153.13 CDJ69079.1 - 0.055 13.5 8.5 0.096 12.7 8.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit dTDP_sugar_isom PF00908.17 CDJ69079.1 - 0.073 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase DUF2722 PF10846.8 CDJ69079.1 - 4.1 6.2 10.4 6 5.7 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) XRCC4 PF06632.12 CDJ69080.1 - 0.0079 15.1 0.1 0.0079 15.1 0.1 5.3 6 1 0 6 6 6 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4667 PF15700.5 CDJ69080.1 - 0.3 11.1 0.0 0.3 11.1 0.0 8.8 4 3 3 7 7 7 0 Domain of unknown function (DUF4667) HMG_box PF00505.19 CDJ69081.1 - 4.8e-22 78.2 5.0 7.7e-22 77.5 5.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ69081.1 - 1.6e-15 57.4 4.2 2.6e-15 56.7 4.2 1.3 1 0 0 1 1 1 1 HMG-box domain KRAB PF01352.27 CDJ69081.1 - 0.027 14.1 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 KRAB box RED_N PF07808.13 CDJ69082.1 - 0.0024 17.5 2.7 0.0024 17.5 2.7 3.3 1 1 2 3 3 3 1 RED-like protein N-terminal region DUF3464 PF11947.8 CDJ69082.1 - 0.4 10.4 0.0 0.4 10.4 0.0 4.6 5 0 0 5 5 5 0 Photosynthesis affected mutant 68 SR-25 PF10500.9 CDJ69083.1 - 1.4e-05 24.9 36.7 0.0089 15.7 6.6 3.8 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ69083.1 - 0.00021 21.0 13.4 0.00021 21.0 13.4 5.8 5 1 0 6 6 6 1 Spt20 family DUF4667 PF15700.5 CDJ69083.1 - 0.011 15.9 0.9 0.011 15.9 0.9 3.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4667) UPF0524 PF15823.5 CDJ69083.1 - 0.011 15.1 3.4 0.011 15.1 3.4 2.6 3 0 0 3 3 3 0 UPF0524 of C3orf70 Allantoicase PF03561.15 CDJ69083.1 - 0.24 11.4 1.6 0.68 9.9 1.6 1.9 1 0 0 1 1 1 0 Allantoicase repeat EphA2_TM PF14575.6 CDJ69083.1 - 0.45 11.4 5.4 0.18 12.7 0.9 2.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain GET2 PF08690.10 CDJ69084.1 - 0.0071 16.1 5.2 0.0071 16.1 5.2 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 Pex14_N PF04695.13 CDJ69084.1 - 0.0074 17.0 10.1 0.0074 17.0 10.1 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ69084.1 - 0.014 15.4 21.3 0.014 15.4 21.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ69084.1 - 0.026 14.5 10.4 0.024 14.6 10.4 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AIF_C PF14721.6 CDJ69084.1 - 0.038 14.4 2.1 0.04 14.3 2.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Presenilin PF01080.17 CDJ69084.1 - 0.058 12.2 5.9 0.056 12.2 5.9 1.0 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CDJ69084.1 - 0.13 11.6 7.0 0.11 11.8 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Connexin PF00029.19 CDJ69084.1 - 0.13 12.0 2.9 0.13 12.0 2.9 1.1 1 0 0 1 1 1 0 Connexin DUF4834 PF16118.5 CDJ69084.1 - 0.14 13.2 10.4 0.19 12.7 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RICTOR_N PF14664.6 CDJ69084.1 - 0.15 11.0 4.9 0.17 10.9 4.9 1.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Spt20 PF12090.8 CDJ69084.1 - 0.16 11.6 32.8 0.18 11.4 32.8 1.1 1 0 0 1 1 1 0 Spt20 family DDHD PF02862.17 CDJ69084.1 - 0.16 12.1 5.4 0.15 12.2 5.4 1.0 1 0 0 1 1 1 0 DDHD domain EOS1 PF12326.8 CDJ69084.1 - 0.17 11.8 1.5 0.16 11.9 1.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein SpoIIP PF07454.11 CDJ69084.1 - 0.18 11.2 7.7 0.22 11.0 7.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4175 PF13779.6 CDJ69084.1 - 0.22 9.4 21.0 0.19 9.6 21.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Folate_carrier PF01770.18 CDJ69084.1 - 0.27 9.9 3.6 0.29 9.8 3.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier eIF-3_zeta PF05091.12 CDJ69084.1 - 0.32 9.9 13.0 0.3 10.0 13.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF775 PF05603.12 CDJ69084.1 - 0.36 10.3 9.7 0.39 10.2 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4518 PF15008.6 CDJ69084.1 - 0.37 9.9 11.7 0.44 9.7 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Zip PF02535.22 CDJ69084.1 - 0.41 9.8 1.2 0.37 10.0 1.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Orf78 PF06024.12 CDJ69084.1 - 0.45 10.9 3.7 0.48 10.7 3.7 1.1 1 0 0 1 1 1 0 Orf78 (ac78) Rxt3 PF08642.10 CDJ69084.1 - 0.51 11.1 5.3 0.65 10.8 5.3 1.1 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 SprA-related PF12118.8 CDJ69084.1 - 0.51 9.4 18.2 0.46 9.6 18.2 1.0 1 0 0 1 1 1 0 SprA-related family Neur_chan_memb PF02932.16 CDJ69084.1 - 0.55 10.3 3.6 0.51 10.4 3.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1980 PF09323.10 CDJ69084.1 - 0.7 9.8 4.1 0.62 10.0 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) EIIBC-GUT_N PF03612.14 CDJ69084.1 - 1 9.1 8.6 1.2 8.8 8.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TMEM51 PF15345.6 CDJ69084.1 - 1.2 8.9 10.7 1.3 8.8 10.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 OATP PF03137.20 CDJ69084.1 - 1.3 7.2 3.7 1.3 7.2 3.7 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Med15 PF09606.10 CDJ69084.1 - 1.6 7.3 30.5 1.7 7.2 30.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TERB2 PF15101.6 CDJ69084.1 - 2 8.4 17.8 2.5 8.1 17.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NEMP PF10225.9 CDJ69084.1 - 2.1 8.0 4.5 2.3 7.8 4.5 1.0 1 0 0 1 1 1 0 NEMP family Ctr PF04145.15 CDJ69084.1 - 2.3 8.8 4.3 2.7 8.6 4.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family PigN PF04987.14 CDJ69084.1 - 3.3 6.5 5.0 3.2 6.5 5.0 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) CLN3 PF02487.17 CDJ69084.1 - 3.4 6.6 5.7 3.7 6.5 5.7 1.0 1 0 0 1 1 1 0 CLN3 protein SHR3_chaperone PF08229.11 CDJ69084.1 - 6 5.8 8.1 6.7 5.6 8.1 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 DUF3464 PF11947.8 CDJ69084.1 - 7.1 6.4 14.5 9.1 6.0 14.5 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CobT PF06213.12 CDJ69084.1 - 8.4 5.7 16.3 9.6 5.5 16.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AAA_22 PF13401.6 CDJ69085.1 - 2.3e-06 27.9 1.5 3.4e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ69085.1 - 0.00051 20.5 1.0 0.00051 20.5 1.0 4.1 2 1 1 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ69085.1 - 0.005 16.8 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 CDJ69085.1 - 0.058 13.3 4.7 0.33 10.9 4.7 2.3 1 1 0 1 1 1 0 NACHT domain AAA PF00004.29 CDJ69085.1 - 0.059 13.8 0.0 0.059 13.8 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 CDJ69085.1 - 0.098 12.9 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase HSP20 PF00011.21 CDJ69086.1 - 1.2e-11 44.7 0.0 2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ69086.1 - 4.2e-05 23.0 0.0 8.6e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA ACBP PF00887.19 CDJ69089.1 - 6.6e-27 93.6 2.2 7.2e-27 93.4 2.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein TFIIA PF03153.13 CDJ69090.1 - 4.9e-06 26.8 72.2 3.3e-05 24.1 32.5 5.4 4 1 0 4 4 4 3 Transcription factor IIA, alpha/beta subunit BTB_2 PF02214.22 CDJ69090.1 - 0.00022 21.5 0.0 0.00058 20.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Methyltrn_RNA_3 PF02598.17 CDJ69091.1 - 2.3e-60 204.6 0.0 6.5e-44 150.6 0.0 3.3 2 1 0 2 2 2 2 Putative RNA methyltransferase Rxt3 PF08642.10 CDJ69091.1 - 0.092 13.5 7.6 0.055 14.2 4.8 1.9 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Pex14_N PF04695.13 CDJ69091.1 - 0.099 13.3 15.6 0.61 10.7 16.4 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PIP5K PF01504.18 CDJ69091.1 - 0.15 11.3 4.2 0.3 10.3 4.2 1.6 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CBP_BcsG PF11658.8 CDJ69091.1 - 0.25 9.7 4.5 0.35 9.2 4.5 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG FAM176 PF14851.6 CDJ69091.1 - 0.26 11.0 8.8 0.048 13.3 4.3 1.9 2 0 0 2 2 2 0 FAM176 family DDHD PF02862.17 CDJ69091.1 - 0.34 11.0 8.3 0.23 11.6 5.8 1.8 2 0 0 2 2 2 0 DDHD domain DUF4834 PF16118.5 CDJ69091.1 - 0.36 11.8 16.1 1.2 10.1 13.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EOS1 PF12326.8 CDJ69091.1 - 0.36 10.7 2.1 0.65 9.9 2.1 1.4 1 1 0 1 1 1 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ69091.1 - 0.54 9.2 11.9 0.87 8.5 11.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF913 PF06025.12 CDJ69091.1 - 0.62 9.0 7.0 0.78 8.6 5.6 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Serinc PF03348.15 CDJ69091.1 - 1 8.2 3.5 1.8 7.4 3.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ctr PF04145.15 CDJ69091.1 - 1.2 9.8 4.2 1.7 9.3 2.8 1.9 2 0 0 2 2 2 0 Ctr copper transporter family Peroxin-13_N PF04088.13 CDJ69091.1 - 1.8 8.9 7.3 0.36 11.1 3.4 1.7 2 0 0 2 2 2 0 Peroxin 13, N-terminal region CPSF100_C PF13299.6 CDJ69091.1 - 1.9 8.7 12.6 0.63 10.2 9.2 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Suf PF05843.14 CDJ69091.1 - 2.4 8.1 13.0 4.2 7.3 13.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Connexin PF00029.19 CDJ69091.1 - 2.5 7.8 9.2 2.7 7.7 7.3 1.7 2 0 0 2 2 2 0 Connexin CDC45 PF02724.14 CDJ69091.1 - 3.2 5.9 9.4 5.5 5.2 9.4 1.3 1 0 0 1 1 1 0 CDC45-like protein V_ATPase_I PF01496.19 CDJ69091.1 - 4.2 5.2 9.4 6.4 4.6 9.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Folate_carrier PF01770.18 CDJ69091.1 - 4.9 5.8 4.7 8.2 5.0 4.7 1.3 1 0 0 1 1 1 0 Reduced folate carrier EPL1 PF10513.9 CDJ69091.1 - 4.9 7.5 14.4 1.5 9.2 10.3 1.9 2 0 0 2 2 2 0 Enhancer of polycomb-like GNAT_acetyltr_2 PF13718.6 CDJ69091.1 - 5.2 6.4 15.0 25 4.2 11.8 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase 2 SpoIIP PF07454.11 CDJ69091.1 - 5.3 6.4 14.7 0.36 10.2 9.5 1.6 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF1980 PF09323.10 CDJ69091.1 - 7.1 6.5 8.5 2.3 8.1 5.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) FAM60A PF15396.6 CDJ69091.1 - 7.2 6.6 8.7 1.9 8.4 4.8 1.8 2 0 0 2 2 2 0 Protein Family FAM60A CLN3 PF02487.17 CDJ69091.1 - 7.3 5.5 6.9 12 4.8 6.9 1.3 1 0 0 1 1 1 0 CLN3 protein DUF2514 PF10721.9 CDJ69091.1 - 7.4 6.6 13.6 1.1 9.2 9.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2514) Hid1 PF12722.7 CDJ69091.1 - 8.1 4.4 8.5 12 3.9 8.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TERB2 PF15101.6 CDJ69091.1 - 8.2 6.4 15.4 16 5.5 15.4 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CobT PF06213.12 CDJ69091.1 - 8.3 5.7 20.4 0.48 9.8 15.1 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT TFIIA PF03153.13 CDJ69091.1 - 8.3 6.3 29.1 1.4 8.8 25.5 1.4 2 0 0 2 2 1 0 Transcription factor IIA, alpha/beta subunit AIF_C PF14721.6 CDJ69091.1 - 8.8 6.7 11.4 0.97 9.8 6.3 1.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term AdoHcyase PF05221.17 CDJ69092.1 - 2.3e-136 453.8 0.0 2.6e-136 453.6 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CDJ69092.1 - 1.6e-81 272.1 0.7 2.3e-81 271.6 0.7 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CDJ69092.1 - 2.6e-07 30.2 0.1 4.5e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CDJ69092.1 - 0.00012 21.7 0.1 0.00022 20.8 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CDJ69092.1 - 0.0015 18.8 0.2 0.0058 16.9 0.2 2.0 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 CDJ69092.1 - 0.0033 17.5 0.1 0.0078 16.3 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 CDJ69092.1 - 0.073 12.4 3.3 0.084 12.2 0.3 2.6 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MDFI PF15316.6 CDJ69093.1 - 0.00098 19.2 8.8 0.00098 19.2 8.8 4.0 3 2 1 5 5 5 1 MyoD family inhibitor Sin_N PF04801.13 CDJ69093.1 - 0.066 12.4 31.1 0.099 11.8 22.5 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region PRP1_N PF06424.12 CDJ69093.1 - 0.78 10.1 14.8 0.068 13.6 3.2 3.3 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal T2SSF PF00482.23 CDJ69093.1 - 4.7 7.2 10.6 21 5.1 0.8 4.4 5 0 0 5 5 5 0 Type II secretion system (T2SS), protein F RNase_E_G PF10150.9 CDJ69095.1 - 0.055 12.9 1.5 0.068 12.6 1.5 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family DUF3090 PF11290.8 CDJ69095.1 - 0.13 12.0 4.5 0.19 11.5 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) DUF3533 PF12051.8 CDJ69095.1 - 0.36 9.7 1.4 0.4 9.5 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) TFIIA PF03153.13 CDJ69095.1 - 0.37 10.7 9.4 0.38 10.7 9.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ69095.1 - 0.67 9.5 7.4 0.76 9.3 7.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Androgen_recep PF02166.16 CDJ69095.1 - 2.7 6.7 8.0 3 6.6 8.0 1.1 1 0 0 1 1 1 0 Androgen receptor Activator_LAG-3 PF11498.8 CDJ69095.1 - 8.5 5.2 28.8 10 4.9 28.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Endonuclease_NS PF01223.23 CDJ69096.1 - 0.0002 21.2 0.0 0.029 14.2 0.0 3.2 2 1 0 2 2 2 1 DNA/RNA non-specific endonuclease PhnA_Zn_Ribbon PF08274.12 CDJ69097.1 - 0.25 11.3 2.5 0.68 9.9 0.7 2.5 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Peptidase_M14 PF00246.24 CDJ69098.1 - 3.2e-12 46.9 0.4 3.2e-12 46.9 0.4 3.4 3 1 0 3 3 3 1 Zinc carboxypeptidase RskA PF10099.9 CDJ69098.1 - 1.8 8.8 0.0 1.8 8.8 0.0 9.9 4 2 4 9 9 9 0 Anti-sigma-K factor rskA zf-B_box PF00643.24 CDJ69100.1 - 5.4e-05 23.3 13.7 0.016 15.4 2.3 2.3 2 0 0 2 2 2 2 B-box zinc finger CEBP_ZZ PF16366.5 CDJ69100.1 - 0.015 15.5 5.1 0.015 15.5 5.1 2.1 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain SARAF PF06682.12 CDJ69101.1 - 0.00079 19.2 23.4 0.00079 19.2 23.4 3.8 1 1 2 3 3 3 1 SOCE-associated regulatory factor of calcium homoeostasis 7tm_1 PF00001.21 CDJ69102.1 - 0.16 11.3 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF755 PF05501.11 CDJ69102.1 - 0.19 12.0 5.2 0.29 11.4 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Mito_fiss_reg PF05308.11 CDJ69104.1 - 0.0038 17.3 2.1 0.0038 17.3 2.1 1.9 2 1 0 2 2 2 1 Mitochondrial fission regulator SR-25 PF10500.9 CDJ69106.1 - 0.0013 18.4 25.2 0.0013 18.4 25.2 3.0 1 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ69106.1 - 0.0015 18.9 26.6 0.0015 18.9 26.6 4.2 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Kei1 PF08552.11 CDJ69108.1 - 0.0099 15.8 4.1 0.016 15.1 4.1 1.3 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Presenilin PF01080.17 CDJ69108.1 - 0.013 14.3 21.0 0.015 14.1 21.0 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ69108.1 - 0.028 14.2 20.0 0.032 14.1 20.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 CDJ69108.1 - 0.034 12.9 15.0 0.037 12.8 15.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nha1_C PF08619.10 CDJ69108.1 - 0.075 12.2 20.9 0.072 12.3 20.9 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus UPF0560 PF10577.9 CDJ69108.1 - 0.13 10.7 21.7 0.15 10.5 21.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIA PF03153.13 CDJ69108.1 - 0.16 12.0 43.0 0.21 11.5 43.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 CDJ69108.1 - 0.18 10.6 13.8 0.2 10.4 13.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter eIF-3_zeta PF05091.12 CDJ69108.1 - 0.19 10.6 23.9 0.25 10.3 23.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.15 CDJ69108.1 - 0.21 11.1 19.5 0.23 11.0 19.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 CDJ69108.1 - 0.32 9.2 33.9 0.31 9.2 33.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.6 CDJ69108.1 - 0.37 10.8 17.6 0.45 10.5 17.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A HCO3_cotransp PF00955.21 CDJ69108.1 - 0.47 9.2 5.5 0.54 9.0 5.5 1.0 1 0 0 1 1 1 0 HCO3- transporter family DUF913 PF06025.12 CDJ69108.1 - 0.56 9.1 7.4 0.68 8.8 7.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.7 CDJ69108.1 - 0.93 7.5 16.8 1.2 7.2 16.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hamartin PF04388.12 CDJ69108.1 - 0.97 8.0 18.8 1 8.0 18.8 1.0 1 0 0 1 1 1 0 Hamartin protein MDFI PF15316.6 CDJ69108.1 - 0.98 9.5 11.6 1.5 8.8 11.6 1.3 1 0 0 1 1 1 0 MyoD family inhibitor LAP1C PF05609.12 CDJ69108.1 - 1.1 8.3 18.7 1.4 7.9 18.7 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Auxin_canalis PF05703.11 CDJ69108.1 - 1.1 9.2 10.7 1.3 8.9 10.7 1.1 1 0 0 1 1 1 0 Auxin canalisation MCM_bind PF09739.9 CDJ69108.1 - 1.2 7.5 19.6 1.4 7.3 19.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Ctr PF04145.15 CDJ69108.1 - 1.3 9.6 17.8 2.2 8.9 17.8 1.3 1 1 0 1 1 1 0 Ctr copper transporter family CDC45 PF02724.14 CDJ69108.1 - 1.5 7.0 20.7 1.7 6.9 20.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 CDJ69108.1 - 2.3 6.2 18.6 2.9 5.9 18.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Pkinase_fungal PF17667.1 CDJ69108.1 - 2.7 6.6 12.8 3.1 6.4 12.8 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF2151 PF10221.9 CDJ69108.1 - 2.8 6.4 14.2 3.1 6.3 14.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator PNISR PF15996.5 CDJ69108.1 - 2.9 8.1 26.4 3.8 7.7 26.4 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Sec62 PF03839.16 CDJ69108.1 - 3 7.3 16.6 3.9 6.9 16.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF572 PF04502.13 CDJ69108.1 - 3.2 7.3 23.2 4 7.0 23.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Connexin PF00029.19 CDJ69108.1 - 3.9 7.2 21.7 76 2.9 21.7 2.0 1 1 0 1 1 1 0 Connexin Suf PF05843.14 CDJ69108.1 - 4.3 7.2 28.3 5.3 6.9 28.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SLC12 PF03522.15 CDJ69108.1 - 4.3 6.2 22.2 5.2 6.0 22.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Ribonuc_P_40 PF08584.11 CDJ69108.1 - 5.5 6.2 16.4 6.4 6.0 16.4 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Otopetrin PF03189.13 CDJ69108.1 - 5.6 5.7 9.0 7.8 5.2 9.0 1.3 1 0 0 1 1 1 0 Otopetrin DUF4569 PF15133.6 CDJ69108.1 - 8 6.1 22.1 11 5.7 22.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) NLE PF08154.12 CDJ69109.1 - 0.00049 20.6 0.0 0.00081 19.9 0.0 1.2 1 0 0 1 1 1 1 NLE (NUC135) domain SR-25 PF10500.9 CDJ69109.1 - 0.0041 16.8 14.0 0.0053 16.4 14.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ69109.1 - 0.11 13.2 8.8 0.17 12.6 8.8 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Herpes_pp85 PF04637.12 CDJ69109.1 - 8.1 4.7 6.2 9.1 4.6 6.2 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RAP1 PF07218.11 CDJ69109.1 - 8.3 4.6 5.8 9.3 4.4 5.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Dehydrin PF00257.19 CDJ69110.1 - 0.032 14.8 17.4 0.032 14.8 17.4 5.3 2 2 1 3 3 2 0 Dehydrin BPD_transp_2 PF02653.16 CDJ69110.1 - 0.035 13.3 0.1 0.087 12.0 0.0 1.8 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component PI3K_1B_p101 PF10486.9 CDJ69110.1 - 0.13 10.0 20.9 0.17 9.7 20.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RAP1 PF07218.11 CDJ69110.1 - 0.54 8.5 31.8 0.75 8.0 31.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mcm10 PF09332.11 CDJ69110.1 - 1.2 8.5 26.4 0.19 11.1 18.4 2.0 2 0 0 2 2 2 0 Mcm10 replication factor SPX PF03105.19 CDJ69110.1 - 1.3 8.9 41.1 0.084 12.8 32.4 2.0 2 0 0 2 2 2 0 SPX domain Miga PF10265.9 CDJ69110.1 - 2.5 7.0 27.1 0.18 10.8 21.5 1.7 2 0 0 2 2 2 0 Mitoguardin Pol_alpha_B_N PF08418.10 CDJ69110.1 - 2.7 7.9 21.9 4.7 7.1 14.8 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal SLC12 PF03522.15 CDJ69110.1 - 4.1 6.3 18.1 2.4 7.1 14.3 1.9 2 0 0 2 2 2 0 Solute carrier family 12 PNISR PF15996.5 CDJ69110.1 - 6.4 7.0 22.7 8.5 6.6 16.4 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR BORG_CEP PF14957.6 CDJ69110.1 - 7.1 7.8 28.2 9.3 7.4 24.3 2.1 2 0 0 2 2 2 0 Cdc42 effector NST1 PF13945.6 CDJ69110.1 - 7.1 6.7 25.5 5.2 7.1 18.7 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator FAM76 PF16046.5 CDJ69110.1 - 7.5 5.8 24.7 4.3 6.6 19.6 2.1 2 0 0 2 2 2 0 FAM76 protein NPR3 PF03666.13 CDJ69110.1 - 8 5.1 22.0 0.65 8.7 16.4 1.7 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Draxin PF15550.6 CDJ69110.1 - 8.4 6.2 18.3 1.8 8.4 12.1 2.0 2 0 0 2 2 2 0 Draxin Cwf_Cwc_15 PF04889.12 CDJ69110.1 - 9.7 5.8 22.6 1.1 9.0 15.2 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 CDJ69111.1 - 1.1e-06 29.2 10.9 0.69 10.9 0.1 5.7 5 2 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ69111.1 - 0.00013 22.1 0.0 0.28 11.5 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ69111.1 - 0.04 12.6 0.0 3.2 6.3 0.0 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Coiled PF05710.12 CDJ69111.1 - 0.5 11.2 18.3 0.25 12.2 5.3 2.4 2 0 0 2 2 2 0 Coiled coil DUF4667 PF15700.5 CDJ69111.1 - 3.3 7.7 9.9 0.75 9.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) TTL PF03133.15 CDJ69112.1 - 0.0001 21.5 0.9 0.0001 21.5 0.9 3.2 3 0 0 3 3 3 1 Tubulin-tyrosine ligase family SR-25 PF10500.9 CDJ69112.1 - 0.0059 16.2 33.8 0.0059 16.2 33.8 7.2 4 2 3 7 7 7 3 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ69112.1 - 0.0068 16.7 25.8 0.0068 16.7 25.8 7.2 2 2 3 6 6 6 2 Anti-sigma-K factor rskA DUF2367 PF10164.9 CDJ69112.1 - 0.19 12.2 0.1 0.19 12.2 0.1 4.6 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2367) Pkinase PF00069.25 CDJ69113.1 - 6.9e-06 25.6 0.0 1.2e-05 24.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain SUIM_assoc PF16619.5 CDJ69113.1 - 7 6.8 12.4 12 6.1 12.4 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CDJ69114.1 - 0.097 13.3 31.9 0.76 10.4 14.6 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Shadoo PF14999.6 CDJ69114.1 - 0.31 11.1 22.6 0.13 12.3 3.8 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective GTP1_OBG PF01018.22 CDJ69115.1 - 1.9e-16 60.0 0.9 1.9e-16 60.0 0.9 2.5 3 0 0 3 3 3 1 GTP1/OBG MMR_HSR1 PF01926.23 CDJ69115.1 - 1.3e-10 41.3 0.0 5.7e-10 39.3 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Med15 PF09606.10 CDJ69115.1 - 0.0013 17.6 47.5 0.0013 17.6 47.5 2.9 2 1 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal N6_N4_Mtase PF01555.18 CDJ69115.1 - 0.039 13.7 0.0 5.3 6.7 0.0 2.7 2 1 0 2 2 2 0 DNA methylase BAF1_ABF1 PF04684.13 CDJ69115.1 - 0.31 10.1 45.0 0.97 8.4 17.3 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor V_ATPase_I PF01496.19 CDJ69115.1 - 1.1 7.1 43.8 0.5 8.2 19.9 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Roc PF08477.13 CDJ69115.1 - 1.1 9.4 0.0 1.1 9.4 0.0 4.2 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase CDC45 PF02724.14 CDJ69115.1 - 6.3 5.0 44.0 1.3 7.2 16.9 2.1 2 0 0 2 2 2 0 CDC45-like protein Hid1 PF12722.7 CDJ69115.1 - 6.7 4.7 54.0 0.61 8.1 18.0 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 CDJ69115.1 - 9.4 5.1 54.9 1.3 7.9 17.7 2.3 2 0 0 2 2 2 0 Solute carrier family 12 ATP_bind_3 PF01171.20 CDJ69116.1 - 1.1e-10 41.5 0.0 1.1e-10 41.5 0.0 2.6 2 1 0 2 2 2 1 PP-loop family Nop53 PF07767.11 CDJ69116.1 - 0.0049 16.3 13.3 0.0049 16.3 13.3 3.4 3 0 0 3 3 3 1 Nop53 (60S ribosomal biogenesis) Suf PF05843.14 CDJ69116.1 - 0.013 15.5 2.6 0.013 15.5 2.6 4.0 3 1 1 4 4 4 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ69116.1 - 0.077 12.6 71.4 0.062 12.9 7.6 3.6 4 0 0 4 4 4 0 Spt20 family RNase_H2_suC PF08615.11 CDJ69116.1 - 0.21 11.8 9.5 14 5.8 1.4 3.2 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RLL PF10036.9 CDJ69116.1 - 0.23 11.3 34.0 0.47 10.2 3.2 3.4 3 0 0 3 3 3 0 RNA transcription, translation and transport factor protein DUF3807 PF12720.7 CDJ69116.1 - 3.5 7.9 33.6 5.6 7.2 16.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) DUF4770 PF15994.5 CDJ69116.1 - 7 6.8 24.2 2.2 8.5 9.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) ELO PF01151.18 CDJ69118.1 - 3e-38 131.8 7.9 4.2e-38 131.3 7.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3446 PF11928.8 CDJ69118.1 - 3.2 8.1 16.4 0.11 12.8 7.7 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain RSRP PF17069.5 CDJ69119.1 - 0.0036 16.9 10.0 0.0045 16.6 10.0 1.2 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 SR-25 PF10500.9 CDJ69119.1 - 1.3 8.6 15.9 2.1 7.9 15.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ69119.1 - 3.6 5.6 9.6 4.3 5.3 9.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PI3_PI4_kinase PF00454.27 CDJ69120.1 - 4.9e-22 79.0 0.0 4.9e-20 72.4 0.0 2.7 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase CDK2AP PF09806.9 CDJ69121.1 - 0.0078 16.3 1.0 0.0083 16.2 1.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein RabGAP-TBC PF00566.18 CDJ69122.1 - 9.7e-34 116.9 20.2 9.7e-34 116.9 20.2 4.6 3 1 0 3 3 3 2 Rab-GTPase-TBC domain Spt20 PF12090.8 CDJ69123.1 - 0.0033 17.1 26.5 0.0033 17.1 26.5 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ69123.1 - 0.0044 16.0 24.3 0.0045 16.0 24.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ69123.1 - 0.0059 16.6 13.7 0.0065 16.5 13.7 1.0 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Tom22 PF04281.13 CDJ69123.1 - 0.0075 16.1 5.5 0.009 15.8 5.5 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF3837 PF12939.7 CDJ69123.1 - 0.0086 16.5 0.8 0.0094 16.3 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3837) RAG1_imp_bd PF12560.8 CDJ69123.1 - 0.0092 15.5 5.4 0.011 15.3 5.4 1.1 1 0 0 1 1 1 1 RAG1 importin binding zf-C2H2_3rep PF18868.1 CDJ69123.1 - 0.028 15.1 4.8 0.031 14.9 4.8 1.1 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats Pex26 PF07163.12 CDJ69123.1 - 0.039 13.3 11.8 0.043 13.1 11.8 1.1 1 0 0 1 1 1 0 Pex26 protein TFIIF_beta_N PF17683.1 CDJ69123.1 - 0.067 13.9 7.4 0.086 13.5 7.4 1.1 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus CobT PF06213.12 CDJ69123.1 - 0.083 12.3 12.0 0.077 12.4 12.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pex14_N PF04695.13 CDJ69123.1 - 0.095 13.4 13.2 0.097 13.3 13.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDT1_C PF16679.5 CDJ69123.1 - 0.099 13.1 9.4 0.13 12.7 9.4 1.3 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain DUF4407 PF14362.6 CDJ69123.1 - 0.11 11.8 11.3 0.12 11.7 11.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med15 PF09606.10 CDJ69123.1 - 0.11 11.2 23.8 0.1 11.2 23.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Tombus_P33 PF08500.10 CDJ69123.1 - 0.13 12.3 2.4 0.16 12.0 2.4 1.1 1 0 0 1 1 1 0 Tombusvirus p33 DUF3499 PF12005.8 CDJ69123.1 - 0.14 12.8 5.2 0.16 12.6 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) DUF3464 PF11947.8 CDJ69123.1 - 0.15 11.8 8.7 0.17 11.7 8.7 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TFIIA PF03153.13 CDJ69123.1 - 0.16 11.9 26.5 0.18 11.8 26.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Orf78 PF06024.12 CDJ69123.1 - 0.17 12.2 4.4 0.2 12.0 4.4 1.2 1 0 0 1 1 1 0 Orf78 (ac78) RskA PF10099.9 CDJ69123.1 - 0.18 12.1 7.7 0.2 12.0 7.7 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4820 PF16091.5 CDJ69123.1 - 0.18 11.2 8.6 0.23 10.8 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3391 PF11871.8 CDJ69123.1 - 0.18 12.3 14.1 0.22 12.0 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) EIIBC-GUT_N PF03612.14 CDJ69123.1 - 0.18 11.5 9.2 0.19 11.4 9.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus MTABC_N PF16185.5 CDJ69123.1 - 0.18 11.3 3.0 0.22 11.0 3.0 1.1 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region SpoIIP PF07454.11 CDJ69123.1 - 0.26 10.7 10.1 0.26 10.7 10.1 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Glt_symporter PF03616.14 CDJ69123.1 - 0.29 9.8 3.4 0.33 9.6 3.4 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF775 PF05603.12 CDJ69123.1 - 0.4 10.2 11.8 0.42 10.1 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF1840 PF08895.11 CDJ69123.1 - 0.44 10.9 9.8 0.54 10.6 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) TERB2 PF15101.6 CDJ69123.1 - 0.45 10.5 14.3 0.46 10.5 14.3 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Connexin PF00029.19 CDJ69123.1 - 0.5 10.1 5.5 0.5 10.1 5.5 1.1 1 0 0 1 1 1 0 Connexin AIF_C PF14721.6 CDJ69123.1 - 0.55 10.6 6.8 0.56 10.6 6.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DivIC PF04977.15 CDJ69123.1 - 0.58 10.0 17.2 0.88 9.4 17.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Presenilin PF01080.17 CDJ69123.1 - 0.7 8.6 11.0 0.69 8.6 11.0 1.0 1 0 0 1 1 1 0 Presenilin DUF3371 PF11851.8 CDJ69123.1 - 0.7 11.0 12.1 0.81 10.8 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) EPL1 PF10513.9 CDJ69123.1 - 0.79 10.1 11.6 0.79 10.1 11.6 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like YhfC PF10086.9 CDJ69123.1 - 0.79 9.0 3.6 0.86 8.9 3.6 1.1 1 0 0 1 1 1 0 YhfC intramembrane metalloprotease BRF1 PF07741.13 CDJ69123.1 - 0.94 9.9 9.5 1 9.7 9.5 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain GOLD_2 PF13897.6 CDJ69123.1 - 1.1 9.8 4.1 1.2 9.6 4.1 1.0 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking eIF-3_zeta PF05091.12 CDJ69123.1 - 1.2 8.0 13.4 1.2 8.0 13.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FHIPEP PF00771.20 CDJ69123.1 - 1.2 7.5 8.0 1.2 7.5 8.0 1.0 1 0 0 1 1 1 0 FHIPEP family Kei1 PF08552.11 CDJ69123.1 - 1.3 8.8 6.7 1.5 8.7 6.7 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 CPSF100_C PF13299.6 CDJ69123.1 - 1.4 9.1 9.5 1.5 9.0 9.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4175 PF13779.6 CDJ69123.1 - 1.7 6.4 22.8 1.7 6.5 22.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PepSY_TM PF03929.16 CDJ69123.1 - 1.7 8.2 6.0 1.7 8.3 6.0 1.0 1 0 0 1 1 1 0 PepSY-associated TM region OATP PF03137.20 CDJ69123.1 - 1.8 6.8 5.9 1.7 6.8 5.9 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Band_3_cyto PF07565.13 CDJ69123.1 - 1.8 8.3 11.1 1.8 8.3 11.1 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RED_N PF07808.13 CDJ69123.1 - 1.9 8.0 15.6 2.1 7.9 15.6 1.0 1 0 0 1 1 1 0 RED-like protein N-terminal region PhnG PF06754.12 CDJ69123.1 - 1.9 8.4 10.4 2.3 8.2 10.4 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG DUF4770 PF15994.5 CDJ69123.1 - 2 8.6 12.2 2 8.6 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Gastrin PF00918.17 CDJ69123.1 - 2.1 9.3 11.7 2.3 9.2 11.7 1.0 1 0 0 1 1 1 0 Gastrin/cholecystokinin family EOS1 PF12326.8 CDJ69123.1 - 2.2 8.2 5.5 2.2 8.2 5.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein UPF0560 PF10577.9 CDJ69123.1 - 2.2 6.7 15.7 2.1 6.7 15.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DDHD PF02862.17 CDJ69123.1 - 2.2 8.4 9.9 2.3 8.3 9.9 1.1 1 0 0 1 1 1 0 DDHD domain SprA-related PF12118.8 CDJ69123.1 - 2.3 7.3 24.5 2.3 7.3 24.5 1.1 1 0 0 1 1 1 0 SprA-related family GvpL_GvpF PF06386.11 CDJ69123.1 - 2.3 8.1 12.6 2.5 8.0 12.6 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Folate_carrier PF01770.18 CDJ69123.1 - 2.5 6.7 7.1 2.7 6.7 7.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier Ureide_permease PF07168.11 CDJ69123.1 - 3.2 6.4 3.9 3.1 6.5 3.9 1.0 1 0 0 1 1 1 0 Ureide permease DUF1980 PF09323.10 CDJ69123.1 - 3.3 7.6 6.4 3.3 7.6 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Zip PF02535.22 CDJ69123.1 - 3.5 6.7 5.2 3.4 6.8 5.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CLN3 PF02487.17 CDJ69123.1 - 3.5 6.6 8.1 3.3 6.7 8.1 1.0 1 0 0 1 1 1 0 CLN3 protein DUF2126 PF09899.9 CDJ69123.1 - 4.7 5.2 8.4 5 5.1 8.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PAT1 PF09770.9 CDJ69123.1 - 4.8 5.3 20.4 4.5 5.4 20.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TMEM51 PF15345.6 CDJ69123.1 - 5 6.9 12.7 5.1 6.9 12.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Ctr PF04145.15 CDJ69123.1 - 5.7 7.6 5.7 5.8 7.5 5.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family CSG2 PF16965.5 CDJ69123.1 - 6 5.7 6.3 6.3 5.6 6.3 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Neur_chan_memb PF02932.16 CDJ69123.1 - 6.7 6.7 9.5 6.8 6.7 9.5 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 CDJ69123.1 - 6.8 5.5 5.7 7 5.5 5.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) ALMT PF11744.8 CDJ69123.1 - 7.9 5.2 9.1 7.7 5.2 9.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4192 PF13830.6 CDJ69123.1 - 7.9 6.4 8.9 8.7 6.3 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF4199 PF13858.6 CDJ69123.1 - 8.3 6.8 5.8 8 6.8 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Ndc1_Nup PF09531.10 CDJ69123.1 - 9.4 4.8 10.8 9.4 4.8 10.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Roughex PF06020.11 CDJ69123.1 - 9.7 5.2 16.0 10 5.1 16.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein NAM-associated PF14303.6 CDJ69124.1 - 6.2 7.5 0.0 6.2 7.5 0.0 8.6 2 2 2 4 4 4 0 No apical meristem-associated C-terminal domain EMP24_GP25L PF01105.24 CDJ69127.1 - 0.003 17.5 7.8 0.0047 16.9 6.2 2.1 1 1 1 2 2 2 1 emp24/gp25L/p24 family/GOLD GLEYA PF10528.9 CDJ69127.1 - 0.0033 17.8 0.7 0.0087 16.5 0.5 1.9 1 1 0 1 1 1 1 GLEYA domain PepSY_TM PF03929.16 CDJ69127.1 - 0.54 9.9 0.0 0.54 9.9 0.0 2.4 2 1 0 2 2 2 0 PepSY-associated TM region BAF1_ABF1 PF04684.13 CDJ69127.1 - 0.75 8.8 32.0 0.76 8.8 12.6 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor NPR3 PF03666.13 CDJ69127.1 - 8 5.1 25.8 0.98 8.1 6.9 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 EMP24_GP25L PF01105.24 CDJ69128.1 - 2.4e-09 37.4 0.2 2.7e-09 37.2 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MIS13 PF08202.11 CDJ69128.1 - 0.0064 15.8 0.0 0.0069 15.7 0.0 1.0 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Band_7_C PF16200.5 CDJ69128.1 - 0.093 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of band_7 TFIIA PF03153.13 CDJ69129.1 - 0.054 13.5 17.8 0.07 13.1 17.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ69129.1 - 4.4 5.9 24.0 4.7 5.8 24.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Trp_oprn_chp PF09534.10 CDJ69129.1 - 7.7 6.3 43.8 0.72 9.6 7.3 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Spt20 PF12090.8 CDJ69130.1 - 0.017 14.8 25.4 0.076 12.6 18.8 2.5 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ69130.1 - 0.028 13.4 15.9 0.028 13.4 11.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ69130.1 - 0.062 14.3 0.8 0.062 14.3 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ69130.1 - 0.073 12.7 0.2 4.2 7.0 0.4 2.4 2 0 0 2 2 2 0 FAM176 family DUF1980 PF09323.10 CDJ69130.1 - 0.29 11.0 4.2 27 4.6 3.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) POPLD PF08170.12 CDJ69130.1 - 0.74 10.2 5.1 0.99 9.8 0.4 2.8 2 0 0 2 2 2 0 POPLD (NUC188) domain XRN_M PF17846.1 CDJ69130.1 - 1.9 7.3 6.5 4.4 6.2 6.5 1.5 1 0 0 1 1 1 0 Xrn1 helical domain DUF3381 PF11861.8 CDJ69130.1 - 3.2 7.5 10.3 0.79 9.5 6.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Peptidase_M24 PF00557.24 CDJ69131.1 - 1.7e-20 73.6 0.0 1.7e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 DUF2190 PF09956.9 CDJ69131.1 - 0.11 13.0 9.5 0.045 14.2 6.4 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) CRAL_TRIO PF00650.20 CDJ69133.1 - 1.3e-05 25.0 0.0 1.8e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2518 PF10726.9 CDJ69134.1 - 0.15 11.7 0.2 0.45 10.2 0.1 1.7 1 1 1 2 2 2 0 Protein of function (DUF2518) DUF202 PF02656.15 CDJ69134.1 - 0.21 12.1 3.9 0.59 10.6 0.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF202) MgtE PF01769.16 CDJ69134.1 - 0.67 10.3 8.0 6 7.3 6.6 2.4 2 1 0 2 2 2 0 Divalent cation transporter GIDA PF01134.22 CDJ69136.1 - 6.6e-69 232.9 7.9 3e-61 207.7 0.0 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A GIDA_assoc PF13932.6 CDJ69136.1 - 6.2e-09 36.4 0.0 6.2e-09 36.4 0.0 4.8 3 1 1 4 4 4 2 GidA associated domain Acetyltransf_1 PF00583.25 CDJ69137.1 - 1.1e-06 28.9 0.1 2.3e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ69137.1 - 1.5e-05 25.3 0.6 0.00013 22.3 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ69137.1 - 0.0058 16.6 1.4 0.024 14.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SUIM_assoc PF16619.5 CDJ69137.1 - 0.19 11.8 0.3 0.19 11.8 0.3 6.4 4 3 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ69137.1 - 0.46 10.4 50.8 2.2 8.2 18.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 CDJ69138.1 - 2.1e-07 31.5 0.8 0.11 13.4 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ69138.1 - 0.00068 19.9 0.0 0.0071 16.6 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Duffy_binding PF05424.11 CDJ69138.1 - 0.0044 17.1 0.1 0.0044 17.1 0.1 2.3 3 0 0 3 3 3 1 Duffy binding domain RAB3GAP2_N PF14655.6 CDJ69138.1 - 0.005 16.2 9.6 0.043 13.1 0.0 3.1 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus SR-25 PF10500.9 CDJ69138.1 - 0.0062 16.2 7.6 0.0062 16.2 7.6 2.5 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein FliD_N PF02465.18 CDJ69138.1 - 0.02 15.6 6.0 0.02 15.6 6.0 3.2 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 N-terminus DUF3592 PF12158.8 CDJ69138.1 - 0.05 13.7 1.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) DUF4834 PF16118.5 CDJ69138.1 - 0.28 12.2 0.1 0.28 12.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3138 PF11336.8 CDJ69138.1 - 0.45 9.1 6.6 0.87 8.1 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3995 PF13160.6 CDJ69138.1 - 0.93 9.9 7.4 7.9 6.9 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) DUF4446 PF14584.6 CDJ69138.1 - 1.3 9.0 3.6 0.57 10.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Spt20 PF12090.8 CDJ69138.1 - 2.9 7.4 30.3 1.2 8.7 6.5 2.3 2 0 0 2 2 2 0 Spt20 family DUF3275 PF11679.8 CDJ69138.1 - 4.8 7.1 10.2 0.35 10.8 4.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) RR_TM4-6 PF06459.12 CDJ69138.1 - 9.8 5.9 9.3 9.3 6.0 1.4 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF755 PF05501.11 CDJ69139.1 - 0.0031 17.8 28.7 0.0031 17.8 28.7 4.4 3 1 0 4 4 4 2 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ69139.1 - 0.01 15.5 17.6 0.01 15.5 17.6 2.8 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CDJ69139.1 - 0.34 9.1 4.3 0.49 8.6 4.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.13 CDJ69139.1 - 3.8 5.5 42.8 0.0073 14.5 31.6 1.8 1 1 1 2 2 2 0 AF-4 proto-oncoprotein IMCp PF12314.8 CDJ69142.1 - 7.4e-16 58.2 50.9 2.3e-12 47.0 27.7 2.1 1 1 1 2 2 2 2 Inner membrane complex protein IMCp PF12314.8 CDJ69143.1 - 1.7e-25 89.1 55.0 2.5e-24 85.4 36.9 2.1 1 1 1 2 2 2 2 Inner membrane complex protein Drf_FH1 PF06346.12 CDJ69144.1 - 0.027 14.2 9.5 1.4 8.6 0.5 2.7 2 0 0 2 2 2 0 Formin Homology Region 1 Peptidase_M16 PF00675.20 CDJ69147.1 - 0.076 13.0 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) CEP209_CC5 PF16574.5 CDJ69149.1 - 0.04 14.1 1.7 0.079 13.1 0.4 2.0 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 Molybdopterin_N PF18364.1 CDJ69149.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain PNK3P PF08645.11 CDJ69150.1 - 3.1e-39 134.3 0.0 5.6e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CDJ69150.1 - 1.5e-08 34.9 1.5 5.1e-06 26.7 1.5 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ69150.1 - 6.2e-06 26.7 1.1 1.3e-05 25.7 0.2 1.9 2 0 0 2 2 2 1 AAA ATPase domain tRNA_lig_kinase PF08303.11 CDJ69150.1 - 0.00022 21.4 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_28 PF13521.6 CDJ69150.1 - 0.0017 18.6 1.2 0.005 17.1 0.0 2.4 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 CDJ69150.1 - 0.0053 16.7 0.0 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CDJ69150.1 - 0.0063 16.8 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CDJ69150.1 - 0.012 16.1 0.0 0.031 14.8 0.0 1.7 2 0 0 2 2 1 0 ABC transporter AAA_29 PF13555.6 CDJ69150.1 - 0.014 15.1 0.0 0.043 13.5 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 CDJ69150.1 - 0.015 15.8 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 CDJ69150.1 - 0.019 14.9 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 6PF2K PF01591.18 CDJ69150.1 - 0.024 14.0 0.0 5.3 6.3 0.0 2.2 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_25 PF13481.6 CDJ69150.1 - 0.026 14.1 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain HAD PF12710.7 CDJ69150.1 - 0.03 14.7 1.1 0.86 10.0 0.5 3.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.12 CDJ69150.1 - 0.04 13.2 0.0 0.14 11.4 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 CDJ69150.1 - 0.045 13.7 0.8 0.086 12.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 CDJ69150.1 - 0.049 13.6 0.1 0.17 11.9 0.2 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 CDJ69150.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 CDJ69150.1 - 0.068 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 CDJ69150.1 - 0.069 12.6 0.2 0.33 10.4 0.1 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.18 CDJ69150.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DLIC PF05783.11 CDJ69150.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) cobW PF02492.19 CDJ69150.1 - 0.17 11.4 0.1 0.44 10.1 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HAD_2 PF13419.6 CDJ69150.1 - 0.18 11.9 1.7 14 5.8 0.6 3.1 2 2 1 3 3 3 0 Haloacid dehalogenase-like hydrolase NIF PF03031.18 CDJ69150.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase V-ATPase_G PF03179.15 CDJ69151.1 - 0.00013 22.4 9.1 0.00023 21.6 9.1 1.3 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 CDJ69151.1 - 0.00024 20.6 9.2 0.00039 19.9 9.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ATP-synt_B PF00430.18 CDJ69151.1 - 0.0024 18.0 11.1 0.0055 16.8 11.1 1.6 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 CDJ69151.1 - 0.16 12.4 14.9 0.32 11.4 14.9 1.5 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit RRM_1 PF00076.22 CDJ69152.1 - 0.00014 21.7 0.2 0.47 10.3 0.0 3.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DA1-like PF12315.8 CDJ69153.1 - 5.4e-08 32.5 0.5 7.5e-07 28.7 0.5 2.3 1 1 0 1 1 1 1 Protein DA1 DUF2057 PF09829.9 CDJ69153.1 - 1.1 9.4 23.4 2.3 8.3 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2057) Peptidase_S64 PF08192.11 CDJ69154.1 - 0.61 8.5 7.9 0.81 8.1 7.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 RNA_pol_L_2 PF13656.6 CDJ69155.1 - 3.1e-13 49.3 0.0 4.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1400 PF07176.11 CDJ69155.1 - 0.03 14.6 0.9 0.043 14.1 0.9 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) ING PF12998.7 CDJ69156.1 - 0.0013 19.3 0.2 0.0013 19.3 0.2 2.5 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Spt20 PF12090.8 CDJ69156.1 - 0.89 9.1 11.9 1.8 8.1 11.9 1.4 1 0 0 1 1 1 0 Spt20 family PP2C PF00481.21 CDJ69157.1 - 1e-28 100.7 0.0 1.4e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C BRCT_2 PF16589.5 CDJ69157.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain BAF1_ABF1 PF04684.13 CDJ69157.1 - 1.2 8.1 3.3 1.6 7.7 3.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4342 PF14242.6 CDJ69157.1 - 4.6 7.3 8.7 13 5.9 8.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) TALPID3 PF15324.6 CDJ69157.1 - 7.9 4.0 7.4 11 3.5 7.4 1.2 1 0 0 1 1 1 0 Hedgehog signalling target BCIP PF13862.6 CDJ69158.1 - 2.2e-31 109.3 0.2 2.2e-31 109.3 0.2 2.9 2 1 0 2 2 2 1 p21-C-terminal region-binding protein Ribosomal_L15e PF00827.17 CDJ69159.1 - 3.2e-84 281.4 9.9 3.6e-84 281.2 9.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 DUF674 PF05056.12 CDJ69162.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) Btz PF09405.10 CDJ69163.1 - 6.4e-10 39.4 12.6 6.4e-10 39.4 12.6 2.5 3 1 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding DUF908 PF06012.12 CDJ69163.1 - 3.3 7.0 8.6 0.28 10.5 3.8 1.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF908) GDA1_CD39 PF01150.17 CDJ69165.1 - 3.8e-10 39.0 0.9 4.8e-05 22.2 0.6 2.8 3 0 0 3 3 3 2 GDA1/CD39 (nucleoside phosphatase) family RskA PF10099.9 CDJ69168.1 - 0.011 16.1 25.4 0.011 16.1 25.4 5.6 1 1 4 5 5 5 0 Anti-sigma-K factor rskA PAP2 PF01569.21 CDJ69168.1 - 3.8 7.3 8.2 10 5.9 1.6 3.3 3 1 0 3 3 3 0 PAP2 superfamily SUIM_assoc PF16619.5 CDJ69168.1 - 5.2 7.2 50.9 0.3 11.2 9.4 5.0 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 IMUP PF15761.5 CDJ69169.1 - 1.9 9.2 6.1 2.8 8.7 5.8 1.5 1 1 0 1 1 1 0 Immortalisation up-regulated protein RCDG1 PF15725.5 CDJ69169.1 - 7.7 7.0 8.3 0.25 11.8 2.0 1.7 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein DUF2722 PF10846.8 CDJ69170.1 - 0.00023 20.2 1.3 0.00035 19.6 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RCC1_2 PF13540.6 CDJ69170.1 - 0.0054 16.5 0.3 0.026 14.3 0.1 2.2 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat IMUP PF15761.5 CDJ69170.1 - 0.019 15.7 5.8 0.019 15.7 5.8 2.8 3 0 0 3 3 3 0 Immortalisation up-regulated protein MDFI PF15316.6 CDJ69170.1 - 0.03 14.4 0.7 0.03 14.4 0.7 2.4 3 0 0 3 3 3 0 MyoD family inhibitor DUF3488 PF11992.8 CDJ69170.1 - 0.16 10.9 1.1 0.26 10.2 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) SR-25 PF10500.9 CDJ69170.1 - 0.65 9.6 14.5 5.3 6.6 9.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ69170.1 - 1.2 9.1 3.8 1.8 8.5 3.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ69170.1 - 1.4 8.8 17.2 0.13 12.2 12.8 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4667 PF15700.5 CDJ69170.1 - 2.6 8.1 6.1 5.4 7.0 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) DUF5349 PF17298.2 CDJ69170.1 - 5.5 6.7 10.5 14 5.3 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5349) ACDC PF14733.6 CDJ69172.1 - 7.7e-15 55.0 0.1 2.1e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ69172.1 - 7.9e-05 22.8 3.6 0.00023 21.3 3.6 1.8 1 0 0 1 1 1 1 AP2 domain FANCF PF11107.8 CDJ69174.1 - 0.2 10.8 3.4 2.8 7.0 0.3 2.4 2 0 0 2 2 2 0 Fanconi anemia group F protein (FANCF) Gly_transf_sug PF04488.15 CDJ69175.1 - 4.4e-07 30.4 0.0 9.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF974 PF06159.13 CDJ69175.1 - 0.039 13.8 0.0 0.092 12.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF974) Spt20 PF12090.8 CDJ69175.1 - 1.4 8.5 18.4 0.23 11.1 3.8 2.3 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ69175.1 - 2.6 6.9 13.3 0.64 8.9 2.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2722) DUF2423 PF10338.9 CDJ69176.1 - 5e-12 45.9 2.6 1.3e-11 44.5 2.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Ribosomal_60s PF00428.19 CDJ69176.1 - 0.18 12.4 10.5 0.74 10.4 9.9 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_S11 PF00411.19 CDJ69177.1 - 1.2e-30 106.1 3.3 1.2e-30 106.1 3.3 2.3 2 1 0 2 2 2 1 Ribosomal protein S11 RNA_pol_L PF01193.24 CDJ69178.1 - 2.1e-13 49.5 0.0 5.4e-13 48.2 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 CDJ69178.1 - 2.4e-12 47.2 0.0 4.7e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain Fer4_9 PF13187.6 CDJ69178.1 - 0.0027 17.9 0.4 0.006 16.7 0.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CDJ69178.1 - 0.052 14.1 0.7 0.11 13.1 0.7 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain RskA PF10099.9 CDJ69179.1 - 4.6e-05 23.8 0.7 4.6e-05 23.8 0.7 8.7 3 3 4 7 7 7 1 Anti-sigma-K factor rskA SIR2 PF02146.17 CDJ69179.1 - 6.5e-05 22.9 0.0 6.5e-05 22.9 0.0 2.7 4 0 0 4 4 4 1 Sir2 family Hist_deacetyl PF00850.19 CDJ69180.1 - 0.0018 17.8 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_transf_20 PF00982.21 CDJ69181.1 - 3.6e-154 514.0 1.4 3.1e-128 428.4 0.0 3.8 4 0 0 4 4 4 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CDJ69181.1 - 8.1e-13 48.0 0.8 7e-09 35.2 0.0 2.4 1 1 0 2 2 2 2 Trehalose-phosphatase Glycos_transf_1 PF00534.20 CDJ69181.1 - 0.014 15.0 1.2 1.6 8.3 0.0 3.4 4 0 0 4 4 4 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CDJ69181.1 - 0.033 13.9 0.3 0.099 12.3 0.3 1.8 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF3043 PF11241.8 CDJ69181.1 - 0.074 13.1 0.1 0.074 13.1 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3043) RskA PF10099.9 CDJ69181.1 - 0.89 9.8 63.8 0.12 12.7 14.7 6.4 3 1 2 5 5 5 0 Anti-sigma-K factor rskA DUF3796 PF12676.7 CDJ69181.1 - 4.1 7.9 11.8 8.4 6.9 11.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF2742 PF10888.8 CDJ69182.1 - 0.028 14.7 0.1 0.028 14.7 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2742) DUF1645 PF07816.11 CDJ69182.1 - 0.58 10.7 40.5 0.91 10.1 0.4 5.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1645) GRASP55_65 PF04495.14 CDJ69183.1 - 2.3e-15 57.1 0.0 3.6e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain GT87 PF09594.10 CDJ69183.1 - 0.004 16.9 3.0 0.006 16.3 3.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 87 Spt20 PF12090.8 CDJ69183.1 - 0.063 12.9 19.6 0.16 11.6 3.4 2.1 2 0 0 2 2 2 0 Spt20 family SMAP PF15477.6 CDJ69183.1 - 0.067 14.2 4.0 4.9 8.2 0.4 2.4 2 0 0 2 2 2 0 Small acidic protein family Aminotran_1_2 PF00155.21 CDJ69183.1 - 0.27 10.4 1.7 1.6 7.8 0.2 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II Activator_LAG-3 PF11498.8 CDJ69183.1 - 1.2 8.1 23.7 0.41 9.6 2.6 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Pex14_N PF04695.13 CDJ69183.1 - 2.1 9.0 17.3 0.97 10.1 7.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 CDJ69183.1 - 2.9 6.7 14.8 0.91 8.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) PH PF00169.29 CDJ69184.1 - 0.0018 18.7 0.0 0.0035 17.8 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 CDJ69184.1 - 0.061 13.6 0.0 0.095 13.0 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain FtsH_ext PF06480.15 CDJ69184.1 - 0.064 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 FtsH Extracellular LRR_9 PF14580.6 CDJ69185.1 - 7.3e-06 25.6 0.3 1.7e-05 24.4 0.3 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CDJ69185.1 - 0.0012 19.2 3.8 0.53 10.8 0.0 4.6 3 1 2 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ69185.1 - 0.0056 16.4 7.6 0.012 15.3 0.6 3.5 4 0 0 4 4 4 1 Leucine rich repeat SLX9 PF15341.6 CDJ69186.1 - 0.41 11.0 6.8 0.17 12.3 3.2 2.3 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 Apolipoprotein PF01442.18 CDJ69187.1 - 0.004 17.0 0.0 0.039 13.8 0.1 2.0 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain LuxT_C PF18285.1 CDJ69189.1 - 3 8.4 12.5 1.7 9.2 1.0 4.8 4 0 0 4 4 4 0 Tetracycline repressor LuxT C-terminal domain PAN_1 PF00024.26 CDJ69190.1 - 1.4e-10 41.0 0.5 1.9e-06 27.7 0.2 2.6 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 CDJ69190.1 - 6.5e-08 32.4 4.7 7.5e-05 22.5 0.2 2.6 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 CDJ69190.1 - 0.0043 17.2 3.4 0.011 15.8 0.1 2.7 2 0 0 2 2 2 1 PAN-like domain RAP80_UIM PF18282.1 CDJ69190.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif SR-25 PF10500.9 CDJ69191.1 - 0.01 15.5 8.3 0.01 15.5 8.3 5.7 2 2 2 5 5 5 0 Nuclear RNA-splicing-associated protein DNA_ligase_IV PF11411.8 CDJ69192.1 - 1.4e-07 31.5 0.6 2.5e-07 30.7 0.6 1.4 1 0 0 1 1 1 1 DNA ligase IV DNA_ligase_A_M PF01068.21 CDJ69192.1 - 3.5e-07 30.1 0.1 3.5e-07 30.1 0.1 2.2 3 0 0 3 3 2 1 ATP dependent DNA ligase domain DUF2722 PF10846.8 CDJ69192.1 - 8.7e-07 28.2 8.6 4.3e-05 22.7 0.1 7.3 4 1 2 6 6 4 2 Protein of unknown function (DUF2722) DNA_ligase_A_N PF04675.14 CDJ69192.1 - 6.9e-05 23.2 0.0 0.0003 21.2 0.0 2.2 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 CDJ69192.1 - 0.00042 20.7 0.0 0.0019 18.5 0.0 2.1 1 0 0 1 1 1 1 RNA ligase Tetraspanin PF00335.20 CDJ69192.1 - 0.0017 18.1 1.2 0.0072 16.1 1.2 2.1 1 1 0 1 1 1 1 Tetraspanin family Orf78 PF06024.12 CDJ69192.1 - 0.0029 17.9 1.1 0.0029 17.9 1.1 6.5 5 1 2 7 7 6 1 Orf78 (ac78) DUF846 PF05832.12 CDJ69192.1 - 0.021 14.9 1.4 0.048 13.7 1.4 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) Kei1 PF08552.11 CDJ69192.1 - 0.082 12.8 0.1 0.082 12.8 0.1 9.2 6 3 2 8 8 5 0 Inositolphosphorylceramide synthase subunit Kei1 SID-1_RNA_chan PF13965.6 CDJ69192.1 - 0.12 10.8 4.2 0.61 8.4 0.0 2.4 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF1980 PF09323.10 CDJ69192.1 - 0.19 11.6 0.0 0.19 11.6 0.0 5.5 5 1 0 5 5 4 0 Domain of unknown function (DUF1980) DUF747 PF05346.11 CDJ69192.1 - 0.34 10.3 2.9 0.75 9.2 2.9 1.5 1 0 0 1 1 1 0 Eukaryotic membrane protein family DUF4366 PF14283.6 CDJ69192.1 - 0.87 9.6 0.0 0.87 9.6 0.0 7.3 5 2 3 9 9 9 0 Domain of unknown function (DUF4366) HisKA_3 PF07730.13 CDJ69193.1 - 4.9 7.8 7.5 9 6.9 2.4 3.3 2 0 0 2 2 2 0 Histidine kinase YtxH PF12732.7 CDJ69194.1 - 0.00068 20.1 2.4 0.00068 20.1 2.4 2.6 1 1 1 2 2 2 1 YtxH-like protein LEA_4 PF02987.16 CDJ69194.1 - 0.0074 16.3 6.6 0.0074 16.3 6.6 4.2 3 1 0 3 3 3 1 Late embryogenesis abundant protein DUF883 PF05957.13 CDJ69194.1 - 1.8 9.2 23.1 2.4 8.8 1.6 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF2868 PF11067.8 CDJ69195.1 - 0.0097 15.5 1.2 0.016 14.7 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) DUF4231 PF14015.6 CDJ69195.1 - 0.88 10.1 5.0 5 7.7 5.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) BolA PF01722.18 CDJ69196.1 - 7.9e-25 86.9 0.4 1.2e-24 86.3 0.4 1.3 1 0 0 1 1 1 1 BolA-like protein TFIIA PF03153.13 CDJ69196.1 - 0.2 11.6 6.3 0.24 11.3 6.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF_A PF03178.15 CDJ69197.1 - 5.4e-14 52.2 0.0 2.5e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.9 CDJ69197.1 - 2.6e-06 26.4 0.0 4.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PAT1 PF09770.9 CDJ69197.1 - 0.85 7.8 0.0 0.85 7.8 0.0 4.2 5 0 0 5 5 5 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.11 CDJ69197.1 - 2.2 8.3 8.5 6.5 6.7 8.5 1.7 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GREB1 PF15782.5 CDJ69197.1 - 4.8 4.2 10.7 8.9 3.3 10.7 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer V_ATPase_I PF01496.19 CDJ69197.1 - 6.4 4.6 9.3 12 3.7 9.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DRY_EERY PF09750.9 CDJ69197.1 - 6.6 7.0 13.0 27 5.0 13.0 2.0 1 0 0 1 1 1 0 Alternative splicing regulator zf-CCHC PF00098.23 CDJ69198.1 - 2.7e-08 33.5 12.5 3.1e-06 27.0 2.3 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ69198.1 - 0.0026 17.6 0.5 0.0026 17.6 0.5 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ69198.1 - 0.013 15.4 0.9 0.013 15.4 0.9 2.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ69198.1 - 0.019 14.8 2.0 0.019 14.8 2.0 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ69198.1 - 0.065 13.0 5.6 0.45 10.3 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ69198.1 - 0.31 10.8 9.3 0.5 10.1 1.0 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DnaJ_CXXCXGXG PF00684.19 CDJ69198.1 - 0.78 10.1 8.5 2.1 8.8 8.5 1.7 1 1 0 1 1 1 0 DnaJ central domain RVP_2 PF08284.11 CDJ69199.1 - 2.8e-10 40.1 0.0 4.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 CDJ69199.1 - 8.7e-09 35.2 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ69199.1 - 4.5e-08 33.6 0.0 9.8e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ69199.1 - 1.6e-07 31.8 0.0 3.9e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ69199.1 - 0.045 14.1 0.0 0.17 12.2 0.0 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ69199.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 CDJ69200.1 - 6.1e-28 97.2 0.0 1.2e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ69200.1 - 2.8e-27 94.7 0.0 5.3e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ69200.1 - 6.6e-16 58.2 0.6 6.6e-16 58.2 0.6 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CDJ69200.1 - 3.3e-14 53.1 0.2 1.6e-13 50.9 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 CDJ69200.1 - 0.0026 17.9 0.2 0.0062 16.7 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger PPR_2 PF13041.6 CDJ69201.1 - 2.4e-11 43.6 0.0 2.4e-09 37.2 0.0 2.3 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 CDJ69201.1 - 7.9e-08 32.0 2.6 0.14 12.4 0.0 4.2 4 0 0 4 4 4 3 PPR repeat PPR_1 PF12854.7 CDJ69201.1 - 3.7e-07 29.7 0.1 0.017 14.8 0.0 2.5 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.6 CDJ69201.1 - 2.3e-05 24.4 0.0 4.9e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 CDJ69202.1 - 1.4e-31 108.4 0.3 1.5e-15 57.1 0.0 3.3 1 1 2 3 3 3 3 PPR repeat family PPR_1 PF12854.7 CDJ69202.1 - 7.3e-21 73.6 1.3 9.8e-09 34.8 0.0 3.8 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 CDJ69202.1 - 6.2e-20 71.0 0.0 6.3e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 CDJ69202.1 - 1.2e-19 69.1 1.1 2.7e-06 27.2 0.0 4.4 4 1 0 4 4 4 3 PPR repeat PPR_long PF17177.4 CDJ69202.1 - 1.5e-11 44.1 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP SR-25 PF10500.9 CDJ69204.1 - 1.4 8.4 7.3 2.2 7.8 7.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4094 PF13334.6 CDJ69205.1 - 0.0081 16.5 0.1 0.0081 16.5 0.1 5.3 5 2 1 6 6 6 1 Domain of unknown function (DUF4094) DUF2681 PF10883.8 CDJ69205.1 - 0.14 12.6 1.0 0.66 10.4 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SYS1 PF09801.9 CDJ69205.1 - 6 7.0 31.9 7.4e+03 -3.0 31.9 3.1 1 1 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network RskA PF10099.9 CDJ69207.1 - 2.5e-07 31.2 0.1 2.5e-07 31.2 0.1 5.6 1 1 3 5 5 5 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ69207.1 - 0.00022 22.2 17.2 0.061 14.3 0.3 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ69207.1 - 0.00039 20.1 51.2 0.0084 15.7 22.3 3.1 3 0 0 3 3 3 3 Spt20 family LptF_LptG PF03739.14 CDJ69207.1 - 0.0065 15.4 0.3 0.27 10.0 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide export system permease LptF/LptG FA_desaturase PF00487.24 CDJ69207.1 - 0.013 15.3 1.3 0.034 14.0 0.5 2.0 2 0 0 2 2 2 0 Fatty acid desaturase DUF1980 PF09323.10 CDJ69207.1 - 0.08 12.9 5.4 0.94 9.4 1.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) DUF2722 PF10846.8 CDJ69207.1 - 0.11 11.4 42.1 0.057 12.4 17.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) MFS_1_like PF12832.7 CDJ69207.1 - 0.36 9.6 2.0 0.49 9.2 0.3 1.9 2 0 0 2 2 2 0 MFS_1 like family SID-1_RNA_chan PF13965.6 CDJ69207.1 - 0.43 8.9 4.5 3.1 6.1 0.3 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 AIM3 PF17096.5 CDJ69207.1 - 0.58 11.1 17.9 15 6.6 15.4 2.7 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Connexin PF00029.19 CDJ69207.1 - 0.91 9.2 11.0 4.7 6.9 7.9 2.3 2 0 0 2 2 2 0 Connexin CDC45 PF02724.14 CDJ69207.1 - 1.1 7.5 18.3 0.23 9.7 8.0 2.3 2 0 0 2 2 2 0 CDC45-like protein SpoIIP PF07454.11 CDJ69207.1 - 1.1 8.7 15.3 0.41 10.1 8.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 CDJ69207.1 - 3.4 6.4 12.7 0.28 9.9 6.2 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 PPL5 PF18168.1 CDJ69207.1 - 4.1 6.6 10.3 0.61 9.3 4.0 2.2 2 0 0 2 2 2 0 Prim-pol family 5 DUF2371 PF10177.9 CDJ69207.1 - 4.2 7.5 9.9 0.16 12.2 0.4 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Band_3_cyto PF07565.13 CDJ69207.1 - 4.3 7.1 13.4 3.2 7.5 5.8 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain TFB6 PF17110.5 CDJ69207.1 - 4.3 7.0 7.4 15 5.3 5.3 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Peroxin-13_N PF04088.13 CDJ69207.1 - 5 7.4 9.4 50 4.2 5.6 2.7 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Afi1 PF07792.12 CDJ69207.1 - 5.3 7.5 15.0 1.5 9.3 7.2 2.7 3 0 0 3 3 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking O-antigen_lig PF13425.6 CDJ69207.1 - 6.2 5.5 7.1 3.3 6.4 0.0 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein FAM176 PF14851.6 CDJ69207.1 - 6.9 6.3 16.7 1.2 8.7 6.5 2.9 3 0 0 3 3 3 0 FAM176 family AAA_25 PF13481.6 CDJ69208.1 - 7.3e-24 84.4 0.1 2e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain DNA_pol_A_exo1 PF01612.20 CDJ69208.1 - 1.1e-12 48.0 0.0 2.6e-07 30.5 0.1 2.4 2 0 0 2 2 2 2 3'-5' exonuclease Toprim_2 PF13155.6 CDJ69208.1 - 2.5e-08 34.2 0.6 2.6e-07 30.9 0.0 3.3 2 0 0 2 2 1 1 Toprim-like RskA PF10099.9 CDJ69208.1 - 8.4e-07 29.5 1.5 8.4e-07 29.5 1.5 11.6 7 3 3 11 11 7 3 Anti-sigma-K factor rskA ATPase PF06745.13 CDJ69208.1 - 2.6e-05 23.7 0.0 7.3e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 KaiC Toprim_4 PF13662.6 CDJ69208.1 - 0.00015 22.2 0.0 0.0011 19.4 0.0 2.2 2 0 0 2 2 2 1 Toprim domain DUF4574 PF15141.6 CDJ69208.1 - 0.0048 16.8 0.1 0.0048 16.8 0.1 5.1 6 1 1 7 7 4 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 AAA_22 PF13401.6 CDJ69208.1 - 0.013 15.8 3.4 0.015 15.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain SR-25 PF10500.9 CDJ69208.1 - 0.018 14.6 0.3 0.018 14.6 0.3 10.3 9 1 1 10 10 8 0 Nuclear RNA-splicing-associated protein zf-CHC2 PF01807.20 CDJ69208.1 - 0.52 10.2 4.0 1.2 9.0 4.0 1.5 1 0 0 1 1 1 0 CHC2 zinc finger AAA_28 PF13521.6 CDJ69208.1 - 1 9.6 0.0 1 9.6 0.0 5.4 9 0 0 9 9 7 0 AAA domain BUD22 PF09073.10 CDJ69208.1 - 2.4 7.4 78.6 0.0084 15.5 28.5 6.3 6 0 0 6 6 6 0 BUD22 S1 PF00575.23 CDJ69209.1 - 2.6e-27 95.0 0.8 3.1e-15 56.3 0.1 2.1 2 0 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.6 CDJ69209.1 - 0.00013 22.0 0.0 1.5 8.9 0.0 3.3 2 2 0 2 2 2 2 S1 domain CSD PF00313.22 CDJ69209.1 - 0.00029 20.6 0.1 0.06 13.2 0.0 2.3 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain Peptidase_C39_2 PF13529.6 CDJ69209.1 - 0.086 13.4 0.0 0.5 10.9 0.0 1.9 2 0 0 2 2 2 0 Peptidase_C39 like family PCB_OB PF17092.5 CDJ69209.1 - 0.11 13.3 2.4 6.4 7.6 0.2 2.5 2 2 0 2 2 2 0 Penicillin-binding protein OB-like domain DUF501 PF04417.12 CDJ69210.1 - 2.4e-16 59.8 1.9 1.5e-09 37.8 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF501) Ribosomal_60s PF00428.19 CDJ69210.1 - 0.00068 20.2 5.8 0.00068 20.2 5.8 4.5 4 0 0 4 4 4 2 60s Acidic ribosomal protein DUF1995 PF09353.10 CDJ69210.1 - 1.8 8.5 4.1 0.59 10.1 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1995) Apt1 PF10351.9 CDJ69211.1 - 0.087 11.7 7.5 0.087 11.7 7.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PPP4R2 PF09184.11 CDJ69211.1 - 3.4 7.2 8.4 4.1 6.9 8.4 1.3 1 0 0 1 1 1 0 PPP4R2 PEARLI-4 PF05278.12 CDJ69212.1 - 8.9 5.8 23.0 0.042 13.5 10.9 2.9 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) SR-25 PF10500.9 CDJ69213.1 - 0.11 12.1 29.3 0.12 12.0 29.3 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ69213.1 - 0.32 9.0 29.1 0.34 8.9 29.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF445 PF04286.12 CDJ69214.1 - 0.0043 16.9 8.6 0.0046 16.8 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Sirohm_synth_C PF14823.6 CDJ69214.1 - 0.094 12.4 0.6 0.27 10.9 0.6 1.8 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Tam41_Mmp37 PF09139.11 CDJ69214.1 - 0.42 10.0 10.4 0.51 9.7 10.4 1.4 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial GerPC PF10737.9 CDJ69214.1 - 0.53 10.3 21.2 0.75 9.8 21.2 1.2 1 0 0 1 1 1 0 Spore germination protein GerPC WASH-7_mid PF14744.6 CDJ69214.1 - 1.7 7.7 10.3 2.1 7.3 10.3 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 DUF668 PF05003.12 CDJ69214.1 - 3.2 8.3 12.2 13 6.3 4.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF668) MRP-L46 PF11788.8 CDJ69214.1 - 3.7 8.3 14.8 6.2 7.6 14.8 1.4 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 SRP72 PF08492.12 CDJ69214.1 - 4.4 7.8 13.2 47 4.5 13.2 2.3 1 1 0 1 1 1 0 SRP72 RNA-binding domain V_ATPase_I PF01496.19 CDJ69214.1 - 9.7 4.0 11.8 10 3.9 11.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Trp_oprn_chp PF09534.10 CDJ69216.1 - 0.003 17.4 6.2 0.0036 17.1 6.2 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2722 PF10846.8 CDJ69216.1 - 0.048 12.6 21.4 0.048 12.6 21.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4366 PF14283.6 CDJ69216.1 - 0.21 11.6 2.9 0.25 11.4 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) BAF1_ABF1 PF04684.13 CDJ69216.1 - 0.27 10.2 7.9 0.27 10.3 7.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_hydro_9 PF00759.19 CDJ69216.1 - 0.28 10.5 10.3 0.3 10.5 10.3 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Ribosomal_60s PF00428.19 CDJ69216.1 - 0.38 11.4 15.1 0.49 11.0 15.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein EPL1 PF10513.9 CDJ69216.1 - 0.51 10.7 10.1 0.51 10.7 10.1 1.0 1 0 0 1 1 1 0 Enhancer of polycomb-like TAF4 PF05236.14 CDJ69216.1 - 0.62 9.8 11.6 0.63 9.7 11.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Mcm10 PF09332.11 CDJ69216.1 - 0.79 9.1 11.5 0.82 9.0 11.5 1.0 1 0 0 1 1 1 0 Mcm10 replication factor RED_N PF07808.13 CDJ69216.1 - 0.85 9.2 8.4 0.77 9.3 8.4 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Roughex PF06020.11 CDJ69216.1 - 1.1 8.3 18.3 1.1 8.3 18.3 1.0 1 0 0 1 1 1 0 Drosophila roughex protein BAT2_N PF07001.11 CDJ69216.1 - 1.2 9.5 16.3 1.3 9.5 16.3 1.1 1 0 0 1 1 1 0 BAT2 N-terminus Hist_deacetyl PF00850.19 CDJ69216.1 - 1.5 8.2 4.7 1.7 8.0 4.7 1.0 1 0 0 1 1 1 0 Histone deacetylase domain Spt20 PF12090.8 CDJ69216.1 - 1.7 8.2 33.0 1.8 8.1 33.0 1.1 1 0 0 1 1 1 0 Spt20 family DUF3306 PF11748.8 CDJ69216.1 - 2.2 9.2 14.1 2.1 9.2 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF4770 PF15994.5 CDJ69216.1 - 2.2 8.5 8.7 2.2 8.5 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF2232 PF09991.9 CDJ69216.1 - 2.4 7.3 3.9 2.6 7.1 3.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SpoIIP PF07454.11 CDJ69216.1 - 2.8 7.3 7.4 2.5 7.5 7.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Med15 PF09606.10 CDJ69216.1 - 3.2 6.3 26.5 4 6.0 26.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4407 PF14362.6 CDJ69216.1 - 3.3 7.0 17.4 3.3 7.0 17.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.17 CDJ69216.1 - 4 7.5 7.8 3.7 7.6 7.8 1.1 1 0 0 1 1 1 0 DDHD domain Suf PF05843.14 CDJ69216.1 - 4.1 7.3 13.2 3.8 7.4 13.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TMEM51 PF15345.6 CDJ69216.1 - 4.6 7.0 10.9 4.5 7.0 10.9 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 CPSF100_C PF13299.6 CDJ69216.1 - 4.6 7.4 8.5 5 7.3 8.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF5384 PF17358.2 CDJ69216.1 - 7 6.7 26.5 7.9 6.5 26.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5384) TFIIA PF03153.13 CDJ69216.1 - 7.2 6.5 28.6 7.9 6.4 28.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CDJ69216.1 - 8.8 3.3 11.8 8.8 3.3 11.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3446 PF11928.8 CDJ69217.1 - 0.028 14.7 8.2 0.028 14.7 8.2 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain AF-4 PF05110.13 CDJ69217.1 - 0.11 10.5 6.8 0.14 10.2 6.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SDA1 PF05285.12 CDJ69217.1 - 0.63 9.4 3.0 19 4.6 2.9 2.0 2 0 0 2 2 2 0 SDA1 Mucin PF01456.17 CDJ69218.1 - 0.0025 17.8 17.1 0.0025 17.8 17.1 5.6 1 1 3 4 4 4 1 Mucin-like glycoprotein SR-25 PF10500.9 CDJ69219.1 - 0.0085 15.7 17.4 0.0085 15.7 17.4 4.1 2 1 2 4 4 4 2 Nuclear RNA-splicing-associated protein LCD1 PF09798.9 CDJ69219.1 - 0.19 10.2 1.4 0.27 9.7 1.4 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein TFIIA PF03153.13 CDJ69219.1 - 0.32 10.9 17.0 0.036 14.1 12.2 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cation_ATPase_C PF00689.21 CDJ69219.1 - 2.3 7.9 7.6 0.51 10.0 0.8 2.3 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Cwf_Cwc_15 PF04889.12 CDJ69219.1 - 2.5 7.8 7.3 5.1 6.7 7.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Spt20 PF12090.8 CDJ69219.1 - 9.8 5.7 16.3 19 4.8 16.3 1.4 1 0 0 1 1 1 0 Spt20 family E1-E2_ATPase PF00122.20 CDJ69220.1 - 2.7e-17 62.9 0.6 1.5e-12 47.4 0.0 3.4 2 1 1 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 CDJ69220.1 - 1.2e-06 29.0 0.1 1.2e-06 29.0 0.1 4.5 2 2 3 5 5 5 1 haloacid dehalogenase-like hydrolase SUIM_assoc PF16619.5 CDJ69220.1 - 0.0039 17.2 5.1 0.0039 17.2 5.1 14.4 5 5 6 11 11 11 1 Unstructured region C-term to UIM in Ataxin3 Cation_ATPase PF13246.6 CDJ69220.1 - 0.53 10.4 0.0 0.53 10.4 0.0 3.1 3 1 0 3 3 3 0 Cation transport ATPase (P-type) LptF_LptG PF03739.14 CDJ69221.1 - 2.9 6.6 4.8 9.1 5.0 4.8 1.7 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG rve PF00665.26 CDJ69223.1 - 3.8e-08 33.6 0.0 4.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RRM_1 PF00076.22 CDJ69224.1 - 2.5e-16 59.2 0.0 3.6e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PB1 PF00564.24 CDJ69224.1 - 0.11 12.5 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 PB1 domain NYD-SP28_assoc PF14775.6 CDJ69226.1 - 0.24 11.5 0.8 0.8 9.9 0.2 2.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain COPI_assoc PF08507.10 CDJ69229.1 - 5.7e-07 29.6 3.7 7.3e-07 29.3 3.7 1.1 1 0 0 1 1 1 1 COPI associated protein G-patch PF01585.23 CDJ69230.1 - 1.3e-14 53.8 1.1 2.1e-14 53.1 1.1 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ69230.1 - 0.00045 20.3 0.6 0.0013 18.8 0.6 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 CDJ69230.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBP4 PF07960.11 CDJ69230.1 - 0.034 14.0 0.5 0.075 12.9 0.5 1.5 1 0 0 1 1 1 0 CBP4 ALS2CR11 PF15729.5 CDJ69230.1 - 0.22 10.6 0.4 0.31 10.1 0.4 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 AAA_12 PF13087.6 CDJ69231.1 - 1.1e-51 175.3 0.0 2.1e-51 174.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ69231.1 - 1e-43 150.0 3.9 1.6e-26 93.7 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 CDJ69231.1 - 2.6e-11 43.6 0.0 1.1e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ69231.1 - 1.4e-09 38.5 0.0 5.2e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 CDJ69231.1 - 6.4e-05 22.3 0.0 0.0062 15.8 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.9 CDJ69231.1 - 0.00036 19.9 0.2 0.06 12.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CDJ69231.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.16 CDJ69231.1 - 0.002 17.6 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 CDJ69231.1 - 0.0025 17.9 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 CDJ69231.1 - 0.003 18.2 0.2 1 10.1 0.0 3.1 3 0 0 3 3 2 1 Double-stranded RNA binding motif IstB_IS21 PF01695.17 CDJ69231.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 CDJ69231.1 - 0.013 15.2 0.0 1.6 8.4 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 CDJ69231.1 - 0.017 15.5 0.0 0.083 13.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ69231.1 - 0.02 14.6 0.1 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain UvrD-helicase PF00580.21 CDJ69231.1 - 0.031 13.8 0.3 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 CDJ69231.1 - 0.074 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 CDJ69231.1 - 0.092 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CDJ69231.1 - 0.1 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DSPc PF00782.20 CDJ69232.1 - 2e-19 69.7 0.0 3e-17 62.7 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 CDJ69232.1 - 0.0077 16.1 0.0 0.08 12.8 0.0 2.4 2 0 0 2 2 2 1 Gelsolin repeat Y_phosphatase PF00102.27 CDJ69232.1 - 0.064 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase NRBF2 PF08961.10 CDJ69232.1 - 0.073 12.7 0.7 0.88 9.1 0.1 2.4 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator CLU PF13236.6 CDJ69233.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.6 2 0 0 2 2 2 0 Clustered mitochondria TPR_12 PF13424.6 CDJ69234.1 - 0.023 15.0 0.5 0.075 13.3 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MORN PF02493.20 CDJ69235.1 - 6.1e-23 79.3 35.7 0.00093 18.9 0.0 9.2 10 0 0 10 10 10 7 MORN repeat Avl9 PF09794.9 CDJ69235.1 - 2e-11 43.2 0.1 9.3e-11 41.0 0.0 1.6 1 1 1 2 2 2 1 Transport protein Avl9 DENN PF02141.21 CDJ69235.1 - 0.0052 16.8 0.4 0.0052 16.8 0.4 1.7 2 0 0 2 2 2 1 DENN (AEX-3) domain PDZ_6 PF17820.1 CDJ69236.1 - 9.2e-05 22.2 0.0 0.00028 20.7 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ69236.1 - 0.00031 21.0 0.0 0.0006 20.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ69236.1 - 0.088 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PAP2 PF01569.21 CDJ69238.1 - 9.6e-22 77.2 0.7 9.6e-22 77.2 0.7 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CDJ69238.1 - 0.17 12.5 0.3 0.17 12.5 0.3 3.4 4 0 0 4 4 4 0 PAP2 superfamily C-terminal PAP2 PF01569.21 CDJ69239.1 - 1.2e-22 80.1 1.5 1.7e-22 79.7 0.3 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CDJ69239.1 - 1 9.9 4.7 3.1 8.4 0.1 3.1 3 0 0 3 3 3 0 PAP2 superfamily C-terminal ADK PF00406.22 CDJ69240.1 - 4.1e-56 189.3 0.0 6.1e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDJ69240.1 - 4e-29 101.8 0.1 2.1e-28 99.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CDJ69240.1 - 5.8e-17 61.4 1.5 6.6e-17 61.2 0.1 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CDJ69240.1 - 3.1e-09 37.1 0.0 1.3e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 CDJ69240.1 - 6.1e-08 33.2 1.4 3.7e-05 24.1 0.2 2.5 2 1 1 3 3 3 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 CDJ69240.1 - 3e-05 24.6 0.0 9.4e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CDJ69240.1 - 0.0083 16.4 0.1 0.031 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain DAP3 PF10236.9 CDJ69240.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CAML PF14963.6 CDJ69241.1 - 0.043 13.9 1.0 0.065 13.4 1.0 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Hydrolase_4 PF12146.8 CDJ69242.1 - 2.4e-05 23.7 0.1 0.23 10.7 0.0 2.8 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ69242.1 - 0.067 12.8 0.1 0.42 10.2 0.1 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CDJ69242.1 - 0.071 12.9 0.2 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 CDJ69242.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family PEMT PF04191.13 CDJ69243.1 - 0.036 14.5 0.2 0.6 10.5 0.1 2.1 2 0 0 2 2 2 0 Phospholipid methyltransferase Na_Ca_ex PF01699.24 CDJ69244.1 - 1.9e-35 122.0 40.5 1.1e-20 74.1 18.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ribosomal_L37ae PF01780.19 CDJ69245.1 - 6.3e-41 138.4 8.4 7.2e-41 138.2 8.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 CDJ69245.1 - 0.0016 18.4 1.9 0.0023 17.8 1.9 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CDJ69245.1 - 0.012 15.5 1.7 0.022 14.7 1.7 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Elf1 PF05129.13 CDJ69245.1 - 0.022 14.8 1.2 0.04 14.0 1.2 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.6 CDJ69245.1 - 0.026 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CDJ69245.1 - 0.056 13.6 0.2 0.33 11.1 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 CDJ69245.1 - 0.082 12.7 2.1 2.3 8.0 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Di19 PF05605.12 CDJ69245.1 - 0.22 11.9 0.8 0.22 11.9 0.8 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CDJ69245.1 - 1.5 9.3 5.8 0.88 10.1 1.7 2.3 1 1 1 2 2 2 0 Zinc-finger double domain HSP70 PF00012.20 CDJ69246.1 - 6.6e-11 41.1 0.0 8.7e-11 40.7 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein DcuC PF03606.15 CDJ69247.1 - 3.8 5.8 5.2 8.1 4.8 5.2 1.5 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier SCO1-SenC PF02630.14 CDJ69248.1 - 1.4e-25 89.8 0.0 3.4e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 SCO1/SenC DUF2722 PF10846.8 CDJ69248.1 - 0.00047 19.2 13.7 0.001 18.1 13.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Hid1 PF12722.7 CDJ69248.1 - 0.0016 16.7 7.6 0.0022 16.2 7.6 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Mitofilin PF09731.9 CDJ69248.1 - 0.0036 16.2 17.7 0.0036 16.2 17.7 1.6 2 0 0 2 2 2 1 Mitochondrial inner membrane protein SWIB PF02201.18 CDJ69248.1 - 0.012 15.4 0.4 0.029 14.3 0.0 1.9 2 0 0 2 2 1 0 SWIB/MDM2 domain DUF1980 PF09323.10 CDJ69248.1 - 0.054 13.4 2.0 0.089 12.7 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 CDJ69248.1 - 0.14 10.9 8.3 0.22 10.3 8.3 1.4 1 0 0 1 1 1 0 Presenilin TRM13 PF05206.14 CDJ69248.1 - 0.4 10.2 8.7 0.77 9.2 8.7 1.5 1 0 0 1 1 1 0 Methyltransferase TRM13 Plasmodium_Vir PF05795.11 CDJ69248.1 - 0.46 9.9 11.8 0.029 13.8 6.2 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein VIT1 PF01988.19 CDJ69248.1 - 0.47 10.3 9.8 0.09 12.6 6.2 1.7 2 0 0 2 2 2 0 VIT family Zip PF02535.22 CDJ69248.1 - 0.56 9.4 1.9 0.84 8.8 1.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Folate_carrier PF01770.18 CDJ69248.1 - 0.63 8.7 3.0 1.3 7.7 3.0 1.5 1 0 0 1 1 1 0 Reduced folate carrier PAT1 PF09770.9 CDJ69248.1 - 1.3 7.2 20.1 2.4 6.3 20.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chordopox_A13L PF05961.11 CDJ69248.1 - 1.3 9.3 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Orf78 PF06024.12 CDJ69248.1 - 3 8.2 4.4 2.1e+02 2.3 7.8 2.2 2 0 0 2 2 2 0 Orf78 (ac78) CLN3 PF02487.17 CDJ69248.1 - 3.4 6.6 7.0 11 4.9 6.0 2.0 2 0 0 2 2 2 0 CLN3 protein ALMT PF11744.8 CDJ69248.1 - 3.5 6.4 5.8 6.2 5.5 5.8 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Spt20 PF12090.8 CDJ69248.1 - 9.9 5.7 34.1 0.48 10.0 28.1 1.8 2 0 0 2 2 2 0 Spt20 family MAR_sialic_bdg PF10564.9 CDJ69251.1 - 1.3e-06 28.4 0.0 2.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat TFIIA PF03153.13 CDJ69252.1 - 0.27 11.2 53.9 0.31 11.0 53.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Auxin_canalis PF05703.11 CDJ69252.1 - 8.4 6.2 17.6 14 5.5 17.6 1.4 1 0 0 1 1 1 0 Auxin canalisation MAR_sialic_bdg PF10564.9 CDJ69253.1 - 1.8e-43 146.5 13.4 1.5e-14 53.7 0.1 4.1 4 0 0 4 4 4 4 Sialic-acid binding micronemal adhesive repeat Rieske PF00355.26 CDJ69254.1 - 2.1e-16 59.7 0.1 4.2e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 CDJ69254.1 - 3e-09 36.8 0.0 5.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox_2 PF07992.14 CDJ69254.1 - 2.6e-07 30.2 0.0 5.5e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF2722 PF10846.8 CDJ69254.1 - 0.014 14.4 0.2 0.014 14.4 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ69254.1 - 0.019 15.0 20.1 0.13 12.2 1.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Jak1_Phl PF17887.1 CDJ69254.1 - 0.058 13.4 0.3 0.058 13.4 0.3 2.2 4 0 0 4 4 4 0 Jak1 pleckstrin homology-like domain Peptidase_S49_N PF08496.10 CDJ69254.1 - 0.06 13.4 0.1 0.06 13.4 0.1 2.2 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Amino_oxidase PF01593.24 CDJ69254.1 - 0.074 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 CDJ69254.1 - 0.087 13.3 0.0 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Suf PF05843.14 CDJ69254.1 - 3.6 7.5 11.1 5.4 6.9 0.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SR-25 PF10500.9 CDJ69255.1 - 3.6e-06 26.7 98.1 0.0032 17.1 1.3 7.5 8 0 0 8 8 8 5 Nuclear RNA-splicing-associated protein Myb_DNA-binding PF00249.31 CDJ69255.1 - 0.00013 22.1 0.0 0.00031 20.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain TMEM125 PF15109.6 CDJ69255.1 - 0.16 12.3 0.7 1.8 8.9 0.1 2.7 2 0 0 2 2 2 0 TMEM125 protein family Utp12 PF04003.12 CDJ69255.1 - 0.18 12.1 7.5 0.063 13.6 1.9 3.3 2 0 0 2 2 2 0 Dip2/Utp12 Family DUF4238 PF14022.6 CDJ69255.1 - 0.87 9.0 4.8 2.3 7.7 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) DUF3262 PF11660.8 CDJ69256.1 - 0.7 10.3 11.9 2.6 8.5 7.3 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3262) EPL1 PF10513.9 CDJ69256.1 - 1.4 9.3 14.7 0.25 11.7 1.0 2.9 3 0 0 3 3 3 0 Enhancer of polycomb-like Med3 PF11593.8 CDJ69258.1 - 0.84 8.8 28.5 0.028 13.6 6.9 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal CCSAP PF15748.5 CDJ69258.1 - 2.1 8.5 17.3 1.7 8.8 6.2 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Apt1 PF10351.9 CDJ69258.1 - 2.4 6.9 18.3 1.7 7.4 5.6 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ69258.1 - 4.1 7.2 25.0 2.9 7.7 9.2 2.1 2 0 0 2 2 2 0 SPX domain SpoIIIAH PF12685.7 CDJ69258.1 - 7.9 6.2 20.3 7.6 6.3 2.6 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Pkinase PF00069.25 CDJ69260.1 - 7.9e-36 123.8 0.0 2.7e-34 118.7 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ69260.1 - 1.2e-09 37.8 0.0 0.00039 19.8 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase CsgF PF10614.9 CDJ69260.1 - 0.65 10.2 4.8 0.13 12.5 0.4 2.1 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein Sas6_CC PF18594.1 CDJ69260.1 - 3.6 7.5 4.7 0.5 10.2 0.3 1.9 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Acetyltransf_1 PF00583.25 CDJ69262.1 - 1.3e-11 44.8 0.0 1.8e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ69262.1 - 5e-10 39.7 0.0 7.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ69262.1 - 8.9e-10 38.6 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ69262.1 - 9.5e-06 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CDJ69262.1 - 9.8e-05 23.0 0.0 0.00016 22.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ69262.1 - 0.0024 18.0 0.1 0.0096 16.0 0.0 2.0 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Zip PF02535.22 CDJ69264.1 - 1.8e-14 53.7 0.3 1.8e-14 53.7 0.3 4.8 3 1 0 3 3 3 1 ZIP Zinc transporter SR-25 PF10500.9 CDJ69264.1 - 0.0018 18.0 17.1 0.0018 18.0 17.1 5.6 5 1 0 5 5 5 3 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ69264.1 - 0.0086 15.7 13.4 0.0086 15.7 13.4 5.3 5 0 0 5 5 5 3 Spt20 family DUF4834 PF16118.5 CDJ69264.1 - 0.013 16.5 7.0 0.013 16.5 7.0 5.9 5 1 0 5 5 5 0 Domain of unknown function (DUF4834) CLN3 PF02487.17 CDJ69264.1 - 1.1 8.2 23.6 0.14 11.1 5.1 3.4 3 0 0 3 3 3 0 CLN3 protein SID-1_RNA_chan PF13965.6 CDJ69264.1 - 8.2 4.7 12.3 0.22 9.9 0.2 2.9 3 0 0 3 3 3 0 dsRNA-gated channel SID-1 DUF2232 PF09991.9 CDJ69264.1 - 8.7 5.4 8.2 1.1 8.4 0.1 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2232) RIFIN PF02009.16 CDJ69265.1 - 0.92 9.3 13.1 1.3 8.9 13.1 1.3 1 0 0 1 1 1 0 Rifin Peptidase_M16_M PF16187.5 CDJ69266.1 - 9.9e-25 87.4 0.8 1.5e-12 47.4 0.0 3.9 4 0 0 4 4 4 2 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CDJ69266.1 - 0.00036 20.6 0.0 0.0039 17.2 0.1 2.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF1593 PF07632.11 CDJ69266.1 - 0.23 10.8 0.7 0.42 10.0 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) Helicase_C PF00271.31 CDJ69268.1 - 0.13 12.7 0.0 0.45 10.9 0.0 1.9 1 0 0 1 1 1 0 Helicase conserved C-terminal domain HA2 PF04408.23 CDJ69268.1 - 0.22 11.8 0.0 0.22 11.8 0.0 6.4 8 0 0 8 8 8 0 Helicase associated domain (HA2) DUF2722 PF10846.8 CDJ69268.1 - 0.25 10.2 62.3 0.0079 15.2 2.4 7.7 7 0 0 7 7 7 0 Protein of unknown function (DUF2722) Crust_neuro_H PF03858.13 CDJ69269.1 - 0.011 16.5 14.6 12 6.8 0.2 6.0 5 0 0 5 5 5 0 Crustacean neurohormone H UPF0561 PF10573.9 CDJ69269.1 - 0.81 9.8 35.0 0.081 13.1 1.7 5.4 5 0 0 5 5 5 0 Uncharacterised protein family UPF0561 Spt20 PF12090.8 CDJ69270.1 - 0.047 13.3 1.2 0.06 13.0 1.2 1.1 1 0 0 1 1 1 0 Spt20 family DUF2207 PF09972.9 CDJ69270.1 - 0.17 10.6 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM208_SND2 PF05620.11 CDJ69270.1 - 1.6 8.5 4.5 6 6.6 2.3 2.5 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 FmiP_Thoc5 PF09766.9 CDJ69272.1 - 0.13 11.5 3.6 0.16 11.3 3.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 NPR3 PF03666.13 CDJ69272.1 - 2.7 6.7 13.7 3.1 6.5 13.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ69272.1 - 2.8 6.6 13.5 3.7 6.2 13.5 1.3 1 0 0 1 1 1 0 Presenilin SOBP PF15279.6 CDJ69272.1 - 3.1 8.3 18.2 3.7 8.1 18.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2076 PF09849.9 CDJ69272.1 - 7.4 6.5 12.4 9.5 6.2 12.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) GEMIN8 PF15348.6 CDJ69272.1 - 7.6 6.8 12.9 12 6.1 12.9 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 UQ_con PF00179.26 CDJ69273.1 - 7.3e-47 158.5 0.0 8.7e-47 158.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ69273.1 - 0.00025 20.7 0.0 0.0003 20.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ69273.1 - 0.0071 16.6 0.1 0.0078 16.5 0.1 1.3 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 CDJ69273.1 - 0.056 13.3 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain RRM_1 PF00076.22 CDJ69274.1 - 6.5e-27 93.2 0.1 1.2e-15 57.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.14 CDJ69274.1 - 0.0084 16.1 22.5 0.085 12.8 2.9 2.6 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ69274.1 - 0.085 12.8 60.7 0.41 10.6 31.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ69274.1 - 0.2 11.4 19.6 0.086 12.7 6.8 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Endostatin PF06482.11 CDJ69274.1 - 0.27 10.7 20.5 0.053 13.0 8.8 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin eIF-3_zeta PF05091.12 CDJ69274.1 - 5.5 5.8 31.5 2.7 6.9 12.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Utp14 PF04615.13 CDJ69274.1 - 7 5.1 31.7 0.55 8.7 16.9 2.3 2 0 0 2 2 2 0 Utp14 protein Cohesin_load PF10345.9 CDJ69275.1 - 0.02 13.3 0.0 0.027 12.9 0.0 1.1 1 0 0 1 1 1 0 Cohesin loading factor Oxysterol_BP PF01237.18 CDJ69276.1 - 1.2e-55 188.9 0.0 3.6e-39 134.7 0.0 4.2 3 2 1 4 4 4 2 Oxysterol-binding protein PH PF00169.29 CDJ69276.1 - 1.7e-12 47.7 0.2 5.6e-12 46.1 0.2 1.9 2 0 0 2 2 2 1 PH domain betaPIX_CC PF16523.5 CDJ69276.1 - 0.12 12.3 3.9 0.46 10.3 3.9 2.0 1 0 0 1 1 1 0 betaPIX coiled coil Abhydrolase_6 PF12697.7 CDJ69277.1 - 4e-09 37.4 4.8 3.8e-07 30.9 4.9 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ69277.1 - 9.9e-08 31.9 0.1 0.00021 21.0 0.0 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.13 CDJ69277.1 - 0.14 11.8 0.3 0.73 9.5 0.1 2.0 2 0 0 2 2 2 0 PGAP1-like protein SpoIIP PF07454.11 CDJ69279.1 - 1.7 8.1 17.4 0.76 9.2 5.0 3.4 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) SAPS PF04499.15 CDJ69279.1 - 2.9 6.6 15.3 2.1 7.0 7.6 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein TMEM43 PF07787.12 CDJ69280.1 - 9.3e-18 64.5 0.0 1.5e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 43 Mid2 PF04478.12 CDJ69281.1 - 0.0031 17.3 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor FAM176 PF14851.6 CDJ69281.1 - 0.015 15.0 0.0 0.079 12.6 0.0 2.1 2 0 0 2 2 2 0 FAM176 family cEGF PF12662.7 CDJ69281.1 - 0.037 14.0 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like FtsX PF02687.21 CDJ69281.1 - 0.11 13.0 0.1 0.74 10.3 0.0 1.9 2 0 0 2 2 2 0 FtsX-like permease family LRR19-TM PF15176.6 CDJ69281.1 - 0.14 12.1 0.0 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain EGF PF00008.27 CDJ69281.1 - 0.19 12.1 6.5 0.36 11.2 6.5 1.5 1 0 0 1 1 1 0 EGF-like domain TrbC PF04956.13 CDJ69281.1 - 0.72 10.1 5.7 1.8 8.9 0.1 2.3 2 0 0 2 2 2 0 TrbC/VIRB2 family Clp_N PF02861.20 CDJ69282.1 - 0.017 15.2 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component Patched PF02460.18 CDJ69283.1 - 1.5e-104 350.7 0.2 1.8e-65 221.6 0.7 3.0 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 CDJ69283.1 - 3.9e-28 98.2 3.2 3.9e-28 98.2 3.2 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 CDJ69283.1 - 1.7e-05 22.8 11.2 3.2e-05 21.8 11.2 1.3 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Macoilin PF09726.9 CDJ69283.1 - 0.036 12.7 21.8 0.063 11.8 21.8 1.3 1 0 0 1 1 1 0 Macoilin family DUF4525 PF15027.6 CDJ69283.1 - 0.12 12.0 0.8 0.38 10.5 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) SecD_SecF PF02355.16 CDJ69283.1 - 9.7 5.5 22.9 0.075 12.4 4.0 3.3 3 0 0 3 3 3 0 Protein export membrane protein Phage_holin_3_5 PF16085.5 CDJ69283.1 - 9.8 6.4 9.2 20 5.4 0.0 2.8 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III SUIM_assoc PF16619.5 CDJ69284.1 - 0.066 13.3 12.6 14 5.8 0.7 3.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF4520 PF15016.6 CDJ69284.1 - 0.077 13.1 0.1 21 5.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) DUF3591 PF12157.8 CDJ69285.1 - 3.8e-25 88.5 0.0 1.6e-13 50.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3591) Bromodomain PF00439.25 CDJ69285.1 - 3.4e-16 59.1 0.0 6.1e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.6 CDJ69285.1 - 0.0051 16.6 1.3 0.014 15.2 1.3 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CDJ69285.1 - 0.02 14.9 0.4 0.056 13.5 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle HlyIII PF03006.20 CDJ69286.1 - 3.5e-15 56.3 18.7 5.2e-15 55.8 18.7 1.2 1 0 0 1 1 1 1 Haemolysin-III related Gp_dh_C PF02800.20 CDJ69286.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Pkinase PF00069.25 CDJ69287.1 - 6.7e-12 45.3 0.0 2e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 CDJ69287.1 - 1.3e-06 27.9 0.0 0.00023 20.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.17 CDJ69287.1 - 3.4e-06 26.5 0.0 7.3e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase U5_2-snRNA_bdg PF10597.9 CDJ69287.1 - 0.045 13.8 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 Pkinase PF00069.25 CDJ69288.1 - 9e-11 41.6 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ69288.1 - 2.4e-07 30.4 0.0 3.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ69288.1 - 6e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ69289.1 - 2e-10 40.5 0.0 3.5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ69289.1 - 3.4e-06 26.5 0.0 5.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ69289.1 - 8e-05 22.1 0.0 0.00012 21.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kinase-like PF14531.6 CDJ69290.1 - 4.9e-06 26.1 0.0 0.0002 20.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.25 CDJ69290.1 - 7.8e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ69290.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PPI_Ypi1 PF07491.11 CDJ69291.1 - 3.5e-21 74.8 0.8 3.5e-21 74.8 0.8 2.0 1 1 0 2 2 2 1 Protein phosphatase inhibitor SR-25 PF10500.9 CDJ69291.1 - 0.0014 18.3 8.8 0.0016 18.1 8.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.16 CDJ69291.1 - 1.6 8.7 3.5 1.7 8.7 3.5 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ69291.1 - 3.7 6.2 4.8 3.9 6.1 4.8 1.1 1 0 0 1 1 1 0 Presenilin Metallophos PF00149.28 CDJ69293.1 - 0.00023 21.7 0.0 0.00036 21.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 CDJ69294.1 - 6.8e-53 179.7 0.2 1.3e-52 178.8 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ69294.1 - 1.1e-27 97.0 0.3 8.2e-22 77.7 0.2 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ69294.1 - 0.0062 15.4 3.3 1.3 7.7 1.5 2.1 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 CDJ69294.1 - 0.018 14.0 0.9 0.05 12.6 0.7 1.8 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CDJ69294.1 - 0.027 14.4 0.1 0.027 14.4 0.1 2.4 1 1 1 3 3 3 0 Phosphotransferase enzyme family DnaJ PF00226.31 CDJ69295.1 - 1.5e-09 37.8 0.1 6.8e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 DnaJ domain SR-25 PF10500.9 CDJ69295.1 - 0.0029 17.3 6.7 0.0029 17.3 6.7 5.7 5 1 1 6 6 6 1 Nuclear RNA-splicing-associated protein DUF3464 PF11947.8 CDJ69295.1 - 0.033 13.9 0.6 0.64 9.8 0.5 2.8 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 CT47 PF15623.6 CDJ69295.1 - 0.97 9.2 9.6 4.1 7.2 9.6 2.0 1 0 0 1 1 1 0 Cancer/testis gene family 47 COPI_assoc PF08507.10 CDJ69295.1 - 2.4 8.2 7.5 0.25 11.4 0.5 2.6 3 0 0 3 3 3 0 COPI associated protein Anoctamin PF04547.12 CDJ69295.1 - 6.2 5.5 7.3 0.3 9.9 0.4 2.2 3 0 0 3 3 3 0 Calcium-activated chloride channel DUF2722 PF10846.8 CDJ69296.1 - 0.00047 19.2 1.2 0.00047 19.2 1.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ69296.1 - 0.0012 18.9 0.9 0.0012 18.9 0.9 3.2 2 1 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ69296.1 - 0.018 15.1 16.6 0.05 13.6 4.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Maf1 PF09174.10 CDJ69296.1 - 0.076 13.2 0.6 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Maf1 regulator CTD_bind PF04818.13 CDJ69296.1 - 0.12 13.2 0.4 0.35 11.7 0.4 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Spt20 PF12090.8 CDJ69296.1 - 0.22 11.1 29.1 0.53 9.9 5.3 2.1 2 0 0 2 2 2 0 Spt20 family Band_3_cyto PF07565.13 CDJ69296.1 - 0.26 11.0 5.9 1.3 8.8 0.5 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain UPF0542 PF15086.6 CDJ69296.1 - 0.33 10.9 3.1 3.2 7.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 ANAPC_CDC26 PF10471.9 CDJ69296.1 - 0.53 11.2 28.8 1.2 10.0 6.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 WBP-1 PF11669.8 CDJ69296.1 - 0.71 10.5 5.9 1.6 9.4 2.2 2.2 2 0 0 2 2 2 0 WW domain-binding protein 1 Pex14_N PF04695.13 CDJ69296.1 - 1.1 10.0 11.0 1.9 9.1 3.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 CDJ69296.1 - 1.1 10.3 9.6 13 6.8 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3371 PF11851.8 CDJ69296.1 - 1.6 9.8 9.3 12 7.0 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) SARAF PF06682.12 CDJ69296.1 - 2.4 7.7 8.9 12 5.4 0.2 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis RAB3GAP2_N PF14655.6 CDJ69296.1 - 3 7.0 8.6 1.6 7.9 2.9 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2681 PF10883.8 CDJ69296.1 - 6.5 7.2 20.2 1.5 9.3 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) IHABP4_N PF16174.5 CDJ69296.1 - 8 7.0 17.1 11 6.6 2.1 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal eIF-3_zeta PF05091.12 CDJ69296.1 - 8.9 5.2 9.0 17 4.2 3.8 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4667 PF15700.5 CDJ69297.1 - 0.0013 18.9 0.5 0.0013 18.9 0.5 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4667) WDCP PF15390.6 CDJ69297.1 - 0.044 12.2 0.1 0.044 12.2 0.1 1.8 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family SPX PF03105.19 CDJ69297.1 - 2.4 8.0 20.0 5.8 6.7 0.1 2.2 2 0 0 2 2 2 0 SPX domain Methyltransf_31 PF13847.6 CDJ69298.1 - 9e-10 38.5 0.0 2.1e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ69298.1 - 1e-08 35.8 0.1 4.2e-05 24.2 0.1 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ69298.1 - 1.7e-08 35.0 0.1 9e-07 29.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ69298.1 - 1.6e-07 31.4 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ69298.1 - 6.6e-07 30.0 0.1 4.1e-05 24.2 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 CDJ69298.1 - 0.0024 17.6 0.0 0.0046 16.6 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 CDJ69298.1 - 0.027 13.8 0.1 0.64 9.3 0.0 2.0 1 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 CDJ69298.1 - 0.033 13.4 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ribosomal_60s PF00428.19 CDJ69298.1 - 1.7 9.3 11.6 3.5 8.3 11.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Tic110 PF16940.5 CDJ69298.1 - 4.7 5.6 6.8 6.3 5.2 6.8 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter SLX9 PF15341.6 CDJ69299.1 - 3.9e-06 27.3 1.3 3.9e-06 27.3 1.3 2.4 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 RRN9 PF10680.9 CDJ69299.1 - 0.12 12.7 3.6 0.098 13.0 1.6 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor DUF775 PF05603.12 CDJ69299.1 - 1.8 8.1 11.9 2.8 7.4 8.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Spt20 PF12090.8 CDJ69299.1 - 6.2 6.4 24.2 8.2 6.0 24.2 1.3 1 0 0 1 1 1 0 Spt20 family IMUP PF15761.5 CDJ69300.1 - 0.097 13.4 3.8 0.1 13.3 3.8 1.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ69300.1 - 0.47 10.0 6.2 0.43 10.2 6.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CDJ69300.1 - 0.51 10.9 3.1 0.49 10.9 3.1 1.1 1 0 0 1 1 1 0 Dehydrin Collagen PF01391.18 CDJ69301.1 - 0.00014 21.5 29.9 0.00014 21.5 29.9 2.5 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) FTCD_C PF04961.12 CDJ69303.1 - 0.00018 21.3 0.5 0.00022 21.0 0.5 1.1 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase Ribosomal_S21 PF01165.20 CDJ69303.1 - 0.00071 19.2 0.9 0.00089 18.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S21 LidA_Long_CC PF18641.1 CDJ69303.1 - 0.06 13.4 7.9 0.074 13.1 7.9 1.1 1 0 0 1 1 1 0 LidA long coiled-coil domain TFIIA PF03153.13 CDJ69303.1 - 0.13 12.2 10.3 0.14 12.1 10.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ69303.1 - 0.2 11.2 10.7 0.24 11.0 10.7 1.1 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ69303.1 - 0.97 8.6 9.9 1.2 8.3 9.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ69303.1 - 1.8 8.8 12.0 14 6.0 12.0 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA FdhE PF04216.12 CDJ69303.1 - 1.9 8.3 10.1 2.4 8.0 10.1 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation UCH PF00443.29 CDJ69304.1 - 5.3e-24 85.1 0.0 1.4e-23 83.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ69304.1 - 5.4e-10 39.4 8.2 6.6e-06 25.9 0.1 2.9 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF4834 PF16118.5 CDJ69304.1 - 0.014 16.3 0.9 0.059 14.3 0.9 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RskA PF10099.9 CDJ69304.1 - 0.21 11.9 0.0 0.21 11.9 0.0 5.0 3 2 0 3 3 3 0 Anti-sigma-K factor rskA LCIB_C_CA PF18599.1 CDJ69304.1 - 0.3 10.4 5.5 0.05 12.9 0.4 2.1 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases TMEM208_SND2 PF05620.11 CDJ69304.1 - 0.85 9.4 3.2 2.5 7.9 3.2 1.8 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 TFIIA PF03153.13 CDJ69305.1 - 0.092 12.7 27.4 0.15 12.1 27.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ69305.1 - 0.28 11.0 6.2 0.43 10.4 6.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spc7_N PF15402.6 CDJ69305.1 - 0.62 8.3 11.7 0.85 7.8 11.7 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 FGF-BP1 PF06473.12 CDJ69305.1 - 2.4 8.0 17.3 1.6 8.6 15.6 1.5 1 1 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) SLC12 PF03522.15 CDJ69307.1 - 0.88 8.5 33.6 1.1 8.2 33.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Auxin_canalis PF05703.11 CDJ69307.1 - 6.1 6.7 15.0 8.4 6.2 15.0 1.2 1 0 0 1 1 1 0 Auxin canalisation Dicty_REP PF05086.12 CDJ69307.1 - 9 4.1 16.9 9.8 4.0 16.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Exonuc_VII_L PF02601.15 CDJ69308.1 - 0.95 9.0 24.0 1.1 8.8 24.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit eIF3_subunit PF08597.10 CDJ69308.1 - 2 8.2 15.9 2.2 8.1 15.9 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Macoilin PF09726.9 CDJ69308.1 - 2.3 6.7 29.0 2.6 6.5 29.0 1.0 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CDJ69308.1 - 2.3 8.1 45.7 3.1 7.7 45.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CDJ69308.1 - 6.2 6.1 17.1 7.5 5.8 17.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4148 PF13663.6 CDJ69309.1 - 5.4 7.3 18.0 0.14 12.3 4.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Helicase_C PF00271.31 CDJ69312.1 - 1.8e-15 57.2 0.0 3e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RskA PF10099.9 CDJ69313.1 - 0.0076 16.6 3.1 0.0076 16.6 3.1 6.4 1 1 3 4 4 4 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ69316.1 - 0.00033 20.3 22.1 0.012 15.2 11.7 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF4407 PF14362.6 CDJ69316.1 - 0.029 13.7 18.4 0.042 13.2 18.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ORC_WH_C PF18137.1 CDJ69316.1 - 0.46 10.5 14.1 0.15 12.1 11.2 1.6 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF3381 PF11861.8 CDJ69316.1 - 0.59 9.9 24.8 0.026 14.4 6.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Saw1 PF11561.8 CDJ69316.1 - 0.9 9.0 8.0 1.5 8.3 8.0 1.3 1 0 0 1 1 1 0 Single strand annealing-weakened 1 DUF2417 PF10329.9 CDJ69316.1 - 1.5 8.2 5.0 6.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Suf PF05843.14 CDJ69316.1 - 2 8.4 25.8 3.6 7.5 25.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) K_trans PF02705.16 CDJ69316.1 - 3.3 6.1 4.3 4.3 5.7 3.8 1.3 1 1 0 1 1 1 0 K+ potassium transporter PMI_typeI PF01238.21 CDJ69316.1 - 4.5 6.4 13.4 5.8 6.0 13.4 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I Ribosomal_60s PF00428.19 CDJ69317.1 - 0.38 11.4 16.3 0.69 10.5 16.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Macoilin PF09726.9 CDJ69317.1 - 2.5 6.6 6.9 2.5 6.6 6.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF3138 PF11336.8 CDJ69317.1 - 6.4 5.3 11.0 5.9 5.4 11.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4112 PF13430.6 CDJ69318.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) CAF1 PF04857.20 CDJ69320.1 - 4.7e-25 88.4 0.1 5.7e-14 52.0 0.0 2.3 1 1 1 2 2 2 2 CAF1 family ribonuclease APG9 PF04109.16 CDJ69321.1 - 9.9e-43 146.8 0.2 1.2e-42 146.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 SR-25 PF10500.9 CDJ69322.1 - 8.2e-05 22.3 11.0 8.2e-05 22.3 11.0 2.8 3 1 0 3 3 3 2 Nuclear RNA-splicing-associated protein AAA PF00004.29 CDJ69323.1 - 1.9e-78 261.3 7.0 1.1e-41 142.3 0.0 4.7 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ69323.1 - 4.1e-20 71.3 3.0 2.1e-10 40.2 0.2 4.5 3 0 0 3 3 3 3 AAA+ lid domain RuvB_N PF05496.12 CDJ69323.1 - 1.7e-13 50.6 0.0 2.9e-05 23.9 0.0 3.0 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ69323.1 - 1.5e-09 38.4 0.3 7.9e-06 26.4 0.1 6.7 4 3 2 6 6 3 2 AAA ATPase domain AAA_5 PF07728.14 CDJ69323.1 - 2e-09 37.6 0.8 0.0002 21.4 0.0 3.7 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CDJ69323.1 - 1.8e-08 34.7 0.0 9e-06 25.9 0.0 5.4 5 1 0 5 5 3 2 AAA domain Bac_DnaA PF00308.18 CDJ69323.1 - 2.7e-08 33.9 0.0 7.4e-05 22.7 0.0 2.9 2 0 0 2 2 2 2 Bacterial dnaA protein RskA PF10099.9 CDJ69323.1 - 2.9e-07 31.0 6.2 2.9e-07 31.0 6.2 6.4 3 2 3 6 6 2 1 Anti-sigma-K factor rskA TIP49 PF06068.13 CDJ69323.1 - 3.9e-07 29.6 0.2 0.0039 16.5 0.1 2.8 2 1 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 CDJ69323.1 - 6.7e-07 29.7 0.0 0.014 15.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 CDJ69323.1 - 1.3e-06 28.5 0.0 0.002 18.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CDJ69323.1 - 4.5e-06 26.9 13.8 0.008 16.3 0.0 5.0 4 1 0 4 4 3 2 AAA domain (Cdc48 subfamily) TsaE PF02367.17 CDJ69323.1 - 9.6e-06 25.6 0.0 0.22 11.6 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CDJ69323.1 - 2.6e-05 24.8 3.6 0.3 11.6 0.0 3.7 4 0 0 4 4 4 2 AAA domain DUF2722 PF10846.8 CDJ69323.1 - 4.8e-05 22.5 13.4 4.8e-05 22.5 13.4 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF2722) IstB_IS21 PF01695.17 CDJ69323.1 - 8.7e-05 22.3 5.9 0.17 11.6 0.0 3.6 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_7 PF12775.7 CDJ69323.1 - 9.1e-05 22.0 0.0 0.25 10.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 CDJ69323.1 - 0.00074 18.9 0.9 2.1 7.7 0.0 3.5 3 1 0 3 3 3 2 KaiC Mg_chelatase PF01078.21 CDJ69323.1 - 0.00081 18.8 5.6 0.061 12.7 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CDJ69323.1 - 0.00093 19.0 3.2 1.3 8.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.11 CDJ69323.1 - 0.00093 19.1 0.0 1.6 8.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ69323.1 - 0.0013 19.0 16.8 0.088 13.1 0.0 5.0 4 1 1 5 5 4 2 AAA domain ABC_tran PF00005.27 CDJ69323.1 - 0.0063 17.0 13.2 0.31 11.5 0.0 4.3 4 0 0 4 4 4 2 ABC transporter AAA_28 PF13521.6 CDJ69323.1 - 0.008 16.4 0.1 0.11 12.7 0.0 5.3 4 2 2 6 6 4 2 AAA domain NTPase_1 PF03266.15 CDJ69323.1 - 0.014 15.3 0.2 2.5 8.0 0.0 3.0 2 1 0 2 2 2 0 NTPase NACHT PF05729.12 CDJ69323.1 - 0.03 14.3 18.4 0.34 10.8 0.2 5.1 5 0 0 5 5 5 0 NACHT domain ATPase_2 PF01637.18 CDJ69323.1 - 0.034 14.1 0.1 0.5 10.2 0.0 2.6 2 1 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 CDJ69323.1 - 0.062 13.1 0.0 6.6 6.6 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain TRC8_N PF13705.6 CDJ69323.1 - 0.18 10.7 2.0 0.33 9.8 2.0 1.4 1 0 0 1 1 1 0 TRC8 N-terminal domain Parvo_NS1 PF01057.17 CDJ69323.1 - 0.3 10.1 0.0 0.3 10.1 0.0 3.4 4 0 0 4 4 4 0 Parvovirus non-structural protein NS1 EIF4E-T PF10477.9 CDJ69323.1 - 0.3 9.9 27.4 0.87 8.3 11.9 2.3 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E NB-ARC PF00931.22 CDJ69323.1 - 0.64 9.2 0.0 0.64 9.2 0.0 3.4 4 0 0 4 4 2 0 NB-ARC domain AAA_17 PF13207.6 CDJ69323.1 - 1.1 9.7 12.1 2.3 8.7 0.0 4.3 4 0 0 4 4 4 0 AAA domain MecA PF05389.12 CDJ69323.1 - 2.7 7.6 12.0 0.39 10.3 3.7 2.5 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF2722 PF10846.8 CDJ69324.1 - 0.0024 16.9 0.8 0.0024 16.9 0.8 6.6 5 1 1 6 6 6 3 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ69324.1 - 3.3 7.9 96.9 2.5 8.4 0.5 6.8 4 1 1 5 5 5 0 Anti-sigma-K factor rskA Porphobil_deam PF01379.20 CDJ69325.1 - 2.4e-40 138.3 5.8 1.9e-37 128.7 5.8 3.2 1 1 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CDJ69325.1 - 1.3e-11 44.7 0.2 5.6e-11 42.7 0.2 2.2 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Activator_LAG-3 PF11498.8 CDJ69325.1 - 0.0027 16.8 16.0 0.0027 16.8 16.0 3.3 3 0 0 3 3 3 2 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ69325.1 - 0.0088 15.7 16.5 0.0088 15.7 16.5 3.1 3 0 0 3 3 3 2 Spt20 family DUF4834 PF16118.5 CDJ69325.1 - 0.095 13.7 12.4 3.6 8.6 5.2 3.7 4 0 0 4 4 3 0 Domain of unknown function (DUF4834) RPA43_OB PF17875.1 CDJ69325.1 - 0.14 12.8 1.2 13 6.4 0.3 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I eIF_4EBP PF05456.11 CDJ69325.1 - 0.21 11.5 4.6 1 9.3 1.7 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Spore_coat_CotO PF14153.6 CDJ69325.1 - 0.56 10.1 11.2 0.34 10.8 3.9 2.4 2 0 0 2 2 2 0 Spore coat protein CotO EPL1 PF10513.9 CDJ69325.1 - 1.2 9.5 5.6 4.8 7.5 1.9 2.7 2 0 0 2 2 2 0 Enhancer of polycomb-like V_ATPase_I PF01496.19 CDJ69325.1 - 1.3 6.9 4.0 6.2 4.6 0.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NEMP PF10225.9 CDJ69325.1 - 1.4 8.5 3.9 20 4.7 0.2 2.5 2 0 0 2 2 2 0 NEMP family RAB3GAP2_N PF14655.6 CDJ69325.1 - 2.5 7.3 11.2 6.2 6.0 4.0 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus eIF-3_zeta PF05091.12 CDJ69325.1 - 3.1 6.7 8.8 1.4 7.8 3.9 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIIBC-GUT_N PF03612.14 CDJ69325.1 - 5.1 6.8 5.8 7 6.4 1.6 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus TERB2 PF15101.6 CDJ69325.1 - 5.4 7.0 13.4 0.61 10.1 2.5 2.7 3 0 0 3 3 2 0 Telomere-associated protein TERB2 EphA2_TM PF14575.6 CDJ69325.1 - 8.8 7.3 5.7 37 5.3 2.5 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Rpp20 PF12328.8 CDJ69325.1 - 9.5 6.2 7.2 6.6 6.7 1.5 2.5 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Pkinase PF00069.25 CDJ69326.1 - 1.9e-43 148.8 0.0 3e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ69326.1 - 6.2e-20 71.6 0.0 1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ69326.1 - 2.1e-07 30.6 0.0 3.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDJ69326.1 - 0.034 13.1 0.1 0.034 13.1 0.1 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Spt20 PF12090.8 CDJ69326.1 - 0.048 13.3 13.8 0.084 12.5 13.8 1.3 1 0 0 1 1 1 0 Spt20 family APH PF01636.23 CDJ69326.1 - 0.053 13.4 0.1 0.053 13.4 0.1 2.2 3 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 CDJ69326.1 - 0.059 12.7 0.6 0.1 11.9 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4834 PF16118.5 CDJ69326.1 - 0.19 12.7 2.2 19 6.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ69326.1 - 1.3 7.7 5.1 2 7.1 5.1 1.4 1 0 0 1 1 1 0 Presenilin BRF1 PF07741.13 CDJ69326.1 - 5.9 7.3 6.6 89 3.5 0.0 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Guanylate_cyc PF00211.20 CDJ69328.1 - 1.8e-17 63.6 0.2 3.3e-17 62.7 0.2 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 CDJ69329.1 - 1e-17 64.0 7.3 2.2e-05 24.7 0.0 5.3 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ69329.1 - 3.5e-15 55.5 2.1 0.00012 21.8 0.1 5.0 3 1 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 CDJ69329.1 - 5e-08 32.6 0.8 0.0015 18.1 0.1 2.4 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CDJ69329.1 - 8.6e-06 25.4 1.4 0.89 9.8 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 CDJ69329.1 - 0.0013 18.9 7.1 4.6 8.2 0.0 5.8 7 0 0 7 7 7 1 Leucine Rich Repeat BOP1NT PF08145.12 CDJ69334.1 - 0.0035 17.3 0.2 0.0035 17.3 0.2 1.8 2 0 0 2 2 2 1 BOP1NT (NUC169) domain PEP-utilisers_N PF05524.13 CDJ69334.1 - 0.018 15.2 1.0 0.038 14.2 1.0 1.6 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Rootletin PF15035.6 CDJ69334.1 - 1.2 9.1 10.1 2.8 7.9 10.1 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1003 PF06210.11 CDJ69334.1 - 1.9 8.6 5.6 9.9 6.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) Cation_ATPase_N PF00690.26 CDJ69336.1 - 0.00014 21.5 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 CDJ69337.1 - 9.5e-43 145.8 1.6 9.5e-43 145.8 1.6 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ69337.1 - 1e-18 68.4 0.0 2.2e-18 67.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ69337.1 - 4.6e-05 23.4 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDJ69337.1 - 0.0019 18.0 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ69337.1 - 0.2 12.0 0.9 0.55 10.6 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Tubulin PF00091.25 CDJ69338.1 - 3.8e-30 105.6 0.0 1.8e-27 96.8 0.0 2.2 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 CDJ69338.1 - 0.02 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin like RRM_1 PF00076.22 CDJ69339.1 - 2.3e-15 56.2 0.0 5.1e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 CDJ69339.1 - 1.4e-14 53.8 0.1 2.8e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 Surp module cwf21 PF08312.12 CDJ69339.1 - 9.8e-13 48.0 4.1 9.8e-13 48.0 4.1 2.5 2 0 0 2 2 2 1 cwf21 domain Phage_sheath_1 PF04984.14 CDJ69339.1 - 0.0055 16.6 0.6 0.0055 16.6 0.6 2.8 3 0 0 3 3 3 1 Phage tail sheath protein subtilisin-like domain CTK3 PF12243.8 CDJ69339.1 - 0.009 16.0 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Ku_C PF03730.14 CDJ69339.1 - 0.022 15.4 1.7 0.022 15.4 1.7 2.7 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm ATP-synt_Eps PF04627.13 CDJ69340.1 - 2.4e-16 59.4 0.1 3.2e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Spt20 PF12090.8 CDJ69341.1 - 0.061 12.9 7.9 0.098 12.3 7.9 1.3 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ69342.1 - 0.073 13.2 4.1 0.54 10.4 1.2 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Glyco_tran_WecB PF03808.13 CDJ69342.1 - 0.13 12.2 0.5 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Ribosomal_60s PF00428.19 CDJ69343.1 - 1.1 9.9 9.6 0.73 10.5 3.7 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein VirB8 PF04335.13 CDJ69344.1 - 1.3 8.8 8.4 0.17 11.7 0.4 2.7 2 0 0 2 2 2 0 VirB8 protein Peptidase_C48 PF02902.19 CDJ69345.1 - 0.028 14.3 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain Roughex PF06020.11 CDJ69345.1 - 0.27 10.3 10.9 0.48 9.5 10.9 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF3719 PF12516.8 CDJ69345.1 - 0.38 10.5 4.3 1.5 8.6 4.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3719) MORN PF02493.20 CDJ69347.1 - 1.5e-12 46.6 12.0 7.8e-05 22.3 0.1 5.5 5 0 0 5 5 5 4 MORN repeat Folate_rec PF03024.14 CDJ69348.1 - 7.1e-15 55.3 13.1 1e-14 54.8 13.1 1.2 1 0 0 1 1 1 1 Folate receptor family Pinin_SDK_memA PF04696.13 CDJ69348.1 - 0.011 15.7 2.3 0.02 14.9 2.3 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF5076 PF16826.5 CDJ69348.1 - 0.069 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5076) GPS2_interact PF15784.5 CDJ69348.1 - 0.071 13.6 3.5 0.14 12.6 3.5 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Cytadhesin_P30 PF07271.11 CDJ69348.1 - 0.44 10.1 1.0 0.66 9.5 1.0 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 IMS PF00817.20 CDJ69349.1 - 1.3e-38 132.3 0.3 1.3e-38 132.3 0.3 2.4 3 0 0 3 3 3 1 impB/mucB/samB family IMS_C PF11799.8 CDJ69349.1 - 3.1e-11 44.0 0.4 1.3e-10 42.0 0.4 2.1 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CDJ69349.1 - 0.00022 21.4 0.0 0.00049 20.3 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.8 CDJ69349.1 - 0.015 15.5 0.1 0.06 13.6 0.0 2.0 2 0 0 2 2 2 0 Pathogenicity locus SUIM_assoc PF16619.5 CDJ69349.1 - 0.27 11.3 0.1 0.27 11.3 0.1 6.1 5 2 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 mCpol PF18182.1 CDJ69349.1 - 0.4 11.0 2.0 7.7 6.9 0.2 3.3 4 0 0 4 4 4 0 minimal CRISPR polymerase domain DUF2721 PF11026.8 CDJ69349.1 - 1.4 8.8 4.0 1.6 8.6 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) GTP1_OBG PF01018.22 CDJ69351.1 - 7.4e-26 90.6 3.2 3.2e-24 85.3 3.2 2.4 1 1 0 1 1 1 1 GTP1/OBG GTP_EFTU PF00009.27 CDJ69351.1 - 2.6e-07 30.4 0.0 0.00074 19.1 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ69351.1 - 6.8e-07 29.4 0.0 7.9e-06 25.9 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CDJ69351.1 - 9.7e-05 22.1 0.0 0.42 10.4 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 CDJ69351.1 - 0.0011 18.4 0.0 0.02 14.3 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDJ69351.1 - 0.0013 18.7 0.1 0.1 12.5 0.0 2.6 2 1 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 CDJ69351.1 - 0.004 16.5 0.0 0.0086 15.5 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 CDJ69351.1 - 0.015 15.1 0.0 0.93 9.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 CDJ69351.1 - 0.053 12.7 0.0 7.5 5.6 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.6 CDJ69351.1 - 0.058 13.9 0.0 0.058 13.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF1967 PF09269.11 CDJ69351.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) AAA_29 PF13555.6 CDJ69351.1 - 0.094 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 CDJ69351.1 - 0.098 12.9 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CDJ69351.1 - 0.12 12.4 0.5 0.54 10.3 0.0 2.4 3 0 0 3 3 3 0 Dynamin family CbiG_C PF01890.16 CDJ69351.1 - 0.27 11.8 1.9 0.81 10.3 0.1 2.5 2 0 0 2 2 2 0 Cobalamin synthesis G C-terminus AAA_16 PF13191.6 CDJ69351.1 - 1.9 8.8 11.1 0.3 11.4 0.1 3.6 3 1 0 4 4 4 0 AAA ATPase domain zf-C2H2_3rep PF18868.1 CDJ69352.1 - 0.015 16.0 0.5 0.025 15.2 0.1 1.5 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Csm1_N PF18504.1 CDJ69354.1 - 0.056 13.8 0.1 0.056 13.8 0.1 4.5 3 1 1 4 4 4 0 Csm1 N-terminal domain COMM_domain PF07258.14 CDJ69354.1 - 0.099 12.8 1.0 0.26 11.5 0.1 2.2 2 0 0 2 2 2 0 COMM domain MraY_sig1 PF10555.9 CDJ69354.1 - 0.36 10.4 1.7 0.68 9.6 1.7 1.5 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Epimerase PF01370.21 CDJ69355.1 - 2.4e-41 141.8 0.0 3e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ69355.1 - 4.8e-05 22.9 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDJ69355.1 - 0.00022 20.4 0.0 0.00088 18.4 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDJ69355.1 - 0.0043 16.2 0.0 0.0071 15.5 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CDJ69355.1 - 0.057 12.5 0.2 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein BBS2_Mid PF14783.6 CDJ69355.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region TIP49 PF06068.13 CDJ69356.1 - 5.5e-114 381.0 6.1 4.8e-98 328.6 0.2 2.1 2 0 0 2 2 2 2 TIP49 P-loop domain TIP49_C PF17856.1 CDJ69356.1 - 5.3e-19 68.1 0.0 1.3e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA_22 PF13401.6 CDJ69356.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 CDJ69357.1 - 3.3e-07 30.0 0.0 5.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PT PF04886.12 CDJ69357.1 - 1.3e-06 27.9 15.9 6.8e-05 22.3 7.6 3.6 2 1 1 3 3 3 2 PT repeat DUF2722 PF10846.8 CDJ69357.1 - 0.0089 15.0 5.1 0.0089 15.0 5.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ69357.1 - 0.73 9.8 38.8 0.13 12.3 9.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GramPos_pilinD1 PF16555.5 CDJ69357.1 - 6.2 7.0 9.3 2 8.6 1.3 2.3 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain DUF3824 PF12868.7 CDJ69358.1 - 0.0023 18.6 11.9 0.0023 18.6 11.9 4.4 6 0 0 6 6 6 1 Domain of unknwon function (DUF3824) OATP PF03137.20 CDJ69358.1 - 0.01 14.1 0.6 0.01 14.1 0.6 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4179 PF13786.6 CDJ69358.1 - 0.23 12.0 10.3 0.25 11.9 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) SR-25 PF10500.9 CDJ69358.1 - 6.4 6.3 21.5 3.4 7.2 1.4 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Glyco_hydro_38 PF18438.1 CDJ69360.1 - 3.2 7.9 8.7 0.34 11.0 0.2 3.1 2 1 1 3 3 3 0 Glycosyl hydrolases family 38 C-terminal domain 1 DUF3446 PF11928.8 CDJ69360.1 - 3.6 8.0 12.8 0.41 11.0 7.2 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain CTP_transf_1 PF01148.20 CDJ69362.1 - 2.8e-15 56.8 2.6 8.1e-15 55.3 2.6 1.6 1 1 0 1 1 1 1 Cytidylyltransferase family Neur_chan_memb PF02932.16 CDJ69363.1 - 0.022 14.8 2.8 0.031 14.4 2.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ69363.1 - 0.59 8.8 1.9 0.84 8.3 1.9 1.3 1 0 0 1 1 1 0 Presenilin FAM199X PF15814.5 CDJ69363.1 - 2.8 6.9 16.6 3.9 6.5 16.6 1.1 1 0 0 1 1 1 0 Protein family FAM199X Med15 PF09606.10 CDJ69364.1 - 0.0053 15.5 74.8 0.031 13.0 31.0 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4407 PF14362.6 CDJ69364.1 - 0.0069 15.8 27.3 0.06 12.7 5.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ69364.1 - 0.0078 16.3 36.6 0.0078 16.3 36.6 2.6 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit YL1 PF05764.13 CDJ69364.1 - 0.0098 16.0 5.5 0.0098 16.0 5.5 2.8 2 1 1 3 3 3 1 YL1 nuclear protein DUF572 PF04502.13 CDJ69364.1 - 0.4 10.2 32.6 0.82 9.2 6.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) PAT1 PF09770.9 CDJ69364.1 - 0.61 8.3 53.0 0.58 8.4 18.5 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Fusion_gly PF00523.18 CDJ69365.1 - 0.37 9.0 2.3 0.57 8.4 2.3 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Aldedh PF00171.22 CDJ69366.1 - 3.2e-139 464.4 3.1 6.4e-106 354.6 2.7 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DNA_methylase PF00145.17 CDJ69368.1 - 7.5e-18 65.0 4.1 6.5e-08 32.3 0.0 4.4 5 0 0 5 5 5 4 C-5 cytosine-specific DNA methylase RskA PF10099.9 CDJ69368.1 - 0.0047 17.2 4.2 0.0047 17.2 4.2 4.5 4 1 0 5 5 5 1 Anti-sigma-K factor rskA DUF1764 PF08576.10 CDJ69368.1 - 0.45 11.4 6.1 2 9.4 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RR_TM4-6 PF06459.12 CDJ69368.1 - 3.8 7.2 6.9 7.7 6.3 3.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM199X PF15814.5 CDJ69368.1 - 5.2 6.0 12.6 0.34 9.9 5.7 2.3 2 0 0 2 2 2 0 Protein family FAM199X PHD PF00628.29 CDJ69369.1 - 5.4e-10 39.0 9.2 5.4e-10 39.0 9.2 2.5 2 0 0 2 2 1 1 PHD-finger zf-RING_2 PF13639.6 CDJ69369.1 - 5e-07 29.9 11.5 5e-07 29.9 11.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ69369.1 - 8.3e-06 25.6 7.7 8.3e-06 25.6 7.7 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ69369.1 - 0.00076 19.7 17.4 0.0045 17.2 6.0 3.5 2 1 0 2 2 2 2 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ69369.1 - 0.0012 18.7 11.7 0.0012 18.7 11.7 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 CDJ69369.1 - 0.0018 17.8 3.7 0.0041 16.6 3.7 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_4 PF14447.6 CDJ69369.1 - 0.0036 17.1 9.8 0.0036 17.1 9.8 2.2 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDJ69369.1 - 0.0054 16.7 9.2 0.0054 16.7 9.2 2.7 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ69369.1 - 0.0066 16.3 11.6 0.0066 16.3 11.6 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 CDJ69369.1 - 0.014 15.4 2.7 0.032 14.2 2.7 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 CDJ69369.1 - 0.06 13.4 11.6 1.2 9.2 3.0 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CDJ69369.1 - 0.1 12.6 8.4 0.73 9.9 8.4 2.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_10 PF16685.5 CDJ69369.1 - 0.21 11.7 12.0 0.053 13.7 6.7 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 C1_2 PF03107.16 CDJ69369.1 - 1 9.8 8.9 0.84 10.0 5.0 2.7 2 0 0 2 2 2 0 C1 domain SR-25 PF10500.9 CDJ69370.1 - 0.00013 21.7 47.0 0.00013 21.7 47.0 2.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Spore_GerAC PF05504.11 CDJ69370.1 - 0.12 12.6 7.7 0.16 12.2 7.7 1.1 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal DUF3987 PF13148.6 CDJ69370.1 - 0.13 11.2 9.3 0.18 10.8 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Nop53 PF07767.11 CDJ69370.1 - 0.15 11.4 35.7 0.23 10.8 35.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF1168 PF06658.12 CDJ69370.1 - 0.32 10.8 46.3 0.21 11.4 28.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF334 PF03904.13 CDJ69370.1 - 2 7.9 14.1 2.5 7.6 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) PA26 PF04636.13 CDJ69370.1 - 5.7 5.8 13.4 6.5 5.6 13.4 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM199X PF15814.5 CDJ69370.1 - 6.8 5.7 32.0 5.6 5.9 30.9 1.4 1 1 0 1 1 1 0 Protein family FAM199X Peptidase_S8 PF00082.22 CDJ69371.1 - 4.3e-24 85.3 0.1 4.3e-24 85.3 0.1 3.4 4 2 0 4 4 4 1 Subtilase family AAA_22 PF13401.6 CDJ69371.1 - 5e-05 23.6 2.3 0.042 14.1 0.1 3.0 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 CDJ69371.1 - 0.0013 19.2 15.2 0.0013 19.2 15.2 4.4 4 2 0 4 4 4 1 AAA ATPase domain ABC_tran PF00005.27 CDJ69371.1 - 0.011 16.3 0.0 0.027 15.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 CDJ69371.1 - 0.041 13.1 0.1 0.079 12.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF2791 PF10923.8 CDJ69371.1 - 0.049 12.5 0.1 0.11 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) NACHT PF05729.12 CDJ69371.1 - 0.054 13.4 2.7 0.76 9.7 2.7 2.6 1 1 0 1 1 1 0 NACHT domain Carboxyl_trans PF01039.22 CDJ69373.1 - 1.2e-153 512.4 0.0 5.4e-153 510.2 0.0 1.9 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CDJ69373.1 - 2e-52 177.8 0.0 3.6e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CDJ69373.1 - 2.7e-28 98.7 0.0 5.9e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CDJ69373.1 - 4.9e-20 71.6 0.0 1.1e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ACC_central PF08326.12 CDJ69373.1 - 8.4e-16 57.4 0.3 9.7e-10 37.3 0.1 3.2 3 0 0 3 3 3 3 Acetyl-CoA carboxylase, central region Biotin_lipoyl PF00364.22 CDJ69373.1 - 1.7e-10 40.6 0.0 4.6e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 CDJ69373.1 - 4.1e-09 36.2 0.0 1.6e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CDJ69373.1 - 5e-05 23.0 0.0 0.0008 19.2 0.0 2.9 2 0 0 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CDJ69373.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CDJ69373.1 - 0.00026 21.1 0.0 0.00059 19.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 CDJ69373.1 - 0.16 11.9 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Glycine cleavage H-protein LAL_C2 PF18603.1 CDJ69373.1 - 0.32 11.2 3.2 4.6 7.5 0.0 4.2 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 Chorein_N PF12624.7 CDJ69374.1 - 2e-29 102.0 0.0 2e-29 102.0 0.0 2.5 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CDJ69374.1 - 5.5e-16 59.1 1.6 1.1e-14 54.8 0.0 3.3 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 CDJ69374.1 - 1.3e-07 31.3 0.0 3.5e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 CDJ69374.1 - 6e-05 23.3 0.0 0.00037 20.8 0.0 2.4 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 CDJ69374.1 - 0.28 10.9 2.3 25 4.6 0.1 3.4 3 0 0 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal Ribosomal_L11_N PF03946.14 CDJ69375.1 - 2.3e-21 75.4 0.1 3.5e-21 74.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CDJ69375.1 - 8.6e-18 64.6 0.1 1.4e-17 63.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF4476 PF14771.6 CDJ69375.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Ribosomal_L30 PF00327.20 CDJ69376.1 - 1.1e-14 54.0 0.9 2.2e-14 53.1 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CDJ69376.1 - 1.3e-13 51.0 18.4 1.3e-13 51.0 18.4 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain DTC PF18102.1 CDJ69378.1 - 1.4e-43 148.2 0.0 5.3e-43 146.4 0.0 1.9 2 0 0 2 2 2 1 Deltex C-terminal domain WWE PF02825.20 CDJ69378.1 - 1.4e-11 44.8 5.8 0.00013 22.5 0.0 3.5 3 0 0 3 3 3 3 WWE domain zf-RING_2 PF13639.6 CDJ69378.1 - 8e-07 29.3 7.8 2.6e-05 24.4 3.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CDJ69378.1 - 9.9e-06 25.2 3.7 0.00075 19.2 0.9 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-rbx1 PF12678.7 CDJ69378.1 - 0.00024 21.3 3.1 0.00024 21.3 3.1 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ69378.1 - 0.00038 20.3 4.7 0.00038 20.3 4.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ69378.1 - 0.0016 18.4 5.2 0.0027 17.6 3.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain PHD PF00628.29 CDJ69378.1 - 0.0085 16.0 2.4 0.0085 16.0 2.4 2.0 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_2 PF13923.6 CDJ69378.1 - 0.037 13.9 8.2 0.065 13.1 4.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ69378.1 - 0.047 13.7 0.5 0.047 13.7 0.5 2.6 3 0 0 3 3 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CDJ69378.1 - 0.088 12.9 4.6 0.063 13.3 1.5 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ69378.1 - 0.52 10.5 8.0 0.26 11.5 4.8 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Caudo_TAP PF02413.17 CDJ69378.1 - 0.6 10.3 8.6 0.18 11.9 5.3 1.8 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK FUSC PF04632.12 CDJ69378.1 - 6.4 5.2 5.7 10 4.5 5.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_S19e PF01090.19 CDJ69379.1 - 1e-51 174.2 0.0 1.2e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 CDJ69379.1 - 0.00098 19.0 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain AP_endonuc_2 PF01261.24 CDJ69380.1 - 1.6e-17 63.6 0.0 2.5e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel ECH_1 PF00378.20 CDJ69383.1 - 8.6e-28 97.3 7.1 2.5e-22 79.4 2.7 2.8 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDJ69383.1 - 1.1e-09 38.3 1.7 6.3e-05 22.6 0.0 2.6 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase SUIM_assoc PF16619.5 CDJ69383.1 - 0.65 10.1 14.9 0.092 12.8 4.2 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ69383.1 - 8.6 5.9 9.0 0.36 10.4 2.3 1.9 2 0 0 2 2 2 0 Spt20 family GCP_C_terminal PF04130.13 CDJ69384.1 - 4.6e-18 65.7 3.5 6.9e-18 65.1 3.5 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Pol_alpha_B_N PF08418.10 CDJ69384.1 - 0.0053 16.8 1.3 0.0053 16.8 1.3 1.9 2 0 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal DUF2722 PF10846.8 CDJ69384.1 - 0.017 14.1 15.0 0.12 11.3 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Tox-WTIP PF15654.6 CDJ69384.1 - 0.31 11.5 0.0 0.31 11.5 0.0 3.1 4 0 0 4 4 4 0 Toxin with a conserved tryptophan and TIP tripeptide motif TMEM51 PF15345.6 CDJ69384.1 - 0.34 10.7 7.1 0.8 9.5 0.5 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 RAB3GAP2_N PF14655.6 CDJ69384.1 - 0.37 10.0 11.8 0.2 10.9 1.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Neur_chan_memb PF02932.16 CDJ69384.1 - 0.55 10.3 4.6 2.4 8.2 2.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 CDJ69384.1 - 0.57 11.2 6.3 8.6 7.4 0.4 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) Peptidase_S30 PF01577.16 CDJ69384.1 - 0.86 9.2 5.1 3.1 7.4 0.3 2.3 2 0 0 2 2 2 0 Potyvirus P1 protease Med11 PF10280.9 CDJ69384.1 - 0.94 9.9 10.8 1.7 9.1 0.8 2.6 2 0 0 2 2 2 0 Mediator complex protein DUF2140 PF09911.9 CDJ69384.1 - 1.5 8.3 7.6 0.3 10.6 0.7 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Clp1 PF06807.14 CDJ69384.1 - 5.3 7.5 7.0 14 6.2 4.5 2.3 2 1 0 2 2 2 0 Pre-mRNA cleavage complex II protein Clp1 Suf PF05843.14 CDJ69384.1 - 5.4 6.9 12.0 5.4 6.9 1.6 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF2791 PF10923.8 CDJ69384.1 - 6.2 5.5 12.0 0.15 10.9 4.9 1.7 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) PspB PF06667.12 CDJ69384.1 - 9.7 6.3 8.6 0.65 10.1 1.9 2.2 2 0 0 2 2 2 0 Phage shock protein B FTZ PF03867.14 CDJ69384.1 - 9.9 5.6 19.1 1.2 8.7 0.7 2.6 2 1 1 3 3 3 0 Fushi tarazu (FTZ), N-terminal region SUIM_assoc PF16619.5 CDJ69384.1 - 10 6.3 37.6 0.72 10.0 9.5 3.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ69385.1 - 0.41 9.5 37.5 0.16 10.9 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ69385.1 - 6.1 6.7 61.9 0.022 14.8 3.8 3.8 3 1 1 4 4 4 0 Transcription factor IIA, alpha/beta subunit Hus1 PF04005.12 CDJ69386.1 - 3.9e-12 45.9 0.0 4.4e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Mob1_phocein PF03637.17 CDJ69387.1 - 3e-24 86.0 0.2 3e-24 86.0 0.2 1.6 2 0 0 2 2 2 1 Mob1/phocein family Neur_chan_memb PF02932.16 CDJ69387.1 - 0.28 11.2 3.4 0.32 11.0 3.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NopRA1 PF16201.5 CDJ69387.1 - 0.29 10.7 8.6 0.8 9.3 0.0 2.3 2 1 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 CLN3 PF02487.17 CDJ69387.1 - 5.2 6.0 5.4 6.1 5.8 5.4 1.2 1 0 0 1 1 1 0 CLN3 protein WD40 PF00400.32 CDJ69388.1 - 2.3e-43 145.3 9.9 7.8e-10 39.2 0.2 9.6 8 1 1 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ69388.1 - 1.3e-16 60.7 0.0 0.00012 22.3 0.0 4.6 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CDJ69388.1 - 0.0051 17.3 0.0 0.0086 16.6 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 CDJ69388.1 - 0.0096 14.9 0.0 0.072 12.0 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CCSAP PF15748.5 CDJ69388.1 - 0.03 14.5 0.9 0.03 14.5 0.9 3.5 3 1 0 3 3 3 0 Centriole, cilia and spindle-associated eIF2A PF08662.11 CDJ69388.1 - 0.041 13.8 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A RskA PF10099.9 CDJ69389.1 - 1.4e-07 32.0 5.0 1.4e-07 32.0 5.0 6.3 3 2 2 6 6 6 2 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ69389.1 - 8.3e-05 22.3 2.8 8.3e-05 22.3 2.8 2.7 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein TMEM51 PF15345.6 CDJ69389.1 - 0.024 14.5 0.4 0.024 14.5 0.4 3.6 3 1 0 4 4 4 0 Transmembrane protein 51 DEAD PF00270.29 CDJ69390.1 - 4.4e-23 81.9 0.0 1.6e-11 44.3 0.0 3.0 3 0 0 3 3 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ69390.1 - 6e-19 68.4 0.0 6e-19 68.4 0.0 2.4 4 0 0 4 4 1 1 Helicase conserved C-terminal domain Macoilin PF09726.9 CDJ69390.1 - 0.0039 15.8 5.1 0.0039 15.8 5.1 2.7 3 0 0 3 3 3 1 Macoilin family SPX PF03105.19 CDJ69390.1 - 0.0061 16.5 10.7 0.0061 16.5 10.7 2.5 3 0 0 3 3 2 1 SPX domain SOBP PF15279.6 CDJ69390.1 - 0.3 11.7 34.7 0.48 11.0 19.8 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein DDRGK PF09756.9 CDJ69390.1 - 0.32 10.6 30.2 0.62 9.6 30.2 1.4 1 0 0 1 1 1 0 DDRGK domain CCSAP PF15748.5 CDJ69390.1 - 0.35 11.0 45.0 0.74 9.9 34.8 2.6 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Nop14 PF04147.12 CDJ69390.1 - 0.56 8.4 29.8 1.7 6.7 0.2 2.1 2 0 0 2 2 2 0 Nop14-like family SMYLE_N PF18615.1 CDJ69390.1 - 0.62 9.6 23.1 2 7.9 1.3 2.4 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Apt1 PF10351.9 CDJ69390.1 - 1.8 7.3 37.5 0.24 10.2 11.0 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ69390.1 - 1.9 7.2 43.0 2.3 6.9 3.9 2.3 2 0 0 2 2 2 0 Presenilin Zip PF02535.22 CDJ69390.1 - 3.8 6.6 19.2 2.7 7.1 11.8 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Otopetrin PF03189.13 CDJ69390.1 - 4 6.1 9.8 0.26 10.0 2.7 2.0 2 0 0 2 2 2 0 Otopetrin SpoIIIAH PF12685.7 CDJ69390.1 - 4.6 7.0 40.1 0.25 11.1 3.5 3.2 3 0 0 3 3 3 0 SpoIIIAH-like protein DUF913 PF06025.12 CDJ69390.1 - 4.9 6.0 24.9 2.3 7.1 1.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) LMBR1 PF04791.16 CDJ69390.1 - 7.3 5.4 6.8 13 4.6 6.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PAT1 PF09770.9 CDJ69390.1 - 8.1 4.6 42.2 0.31 9.3 36.4 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ69390.1 - 9.3 6.2 25.3 8.1 6.4 16.9 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ThiF PF00899.21 CDJ69391.1 - 0.0037 16.7 3.4 0.0051 16.2 0.1 2.5 2 1 1 3 3 3 1 ThiF family Alpha_GJ PF03229.13 CDJ69391.1 - 1.2 9.7 26.5 0.18 12.3 8.3 2.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J Robl_LC7 PF03259.17 CDJ69392.1 - 4.2e-23 80.9 0.1 5.2e-23 80.6 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CDJ69392.1 - 0.00099 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 CDJ69392.1 - 0.056 13.8 0.0 0.074 13.4 0.0 1.3 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain Hydrolase_4 PF12146.8 CDJ69393.1 - 0.0056 16.0 0.0 0.015 14.6 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CDJ69393.1 - 0.05 13.4 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 CDJ69393.1 - 0.064 12.7 0.2 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ69393.1 - 0.068 12.8 0.4 0.096 12.3 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CDJ69393.1 - 0.12 11.9 1.2 1 8.9 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DivIC PF04977.15 CDJ69393.1 - 2.7 7.8 9.9 5.1 6.9 9.9 1.4 1 0 0 1 1 1 0 Septum formation initiator DnaJ PF00226.31 CDJ69394.1 - 4.8e-06 26.6 0.0 5.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CDJ69394.1 - 2.5e-05 24.3 0.0 2.8e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Pam16 BAF1_ABF1 PF04684.13 CDJ69395.1 - 0.0038 16.3 21.6 0.0038 16.3 21.6 1.7 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor Hid1 PF12722.7 CDJ69395.1 - 0.0063 14.7 22.9 0.0062 14.7 22.9 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein RskA PF10099.9 CDJ69395.1 - 0.0072 16.6 14.4 0.0072 16.6 14.4 3.2 1 1 1 2 2 2 1 Anti-sigma-K factor rskA TMEM144 PF07857.12 CDJ69395.1 - 0.84 8.5 2.4 1.2 8.0 2.4 1.2 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters Presenilin PF01080.17 CDJ69395.1 - 0.86 8.3 35.9 1.2 7.8 35.9 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CDJ69395.1 - 2 6.6 24.2 2.6 6.2 24.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3552 PF12072.8 CDJ69396.1 - 0.00097 18.6 39.0 0.00097 18.6 39.0 12.9 6 1 8 14 14 14 3 Domain of unknown function (DUF3552) Pkinase PF00069.25 CDJ69398.1 - 3.4e-08 33.2 0.3 1.4e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Spt20 PF12090.8 CDJ69398.1 - 0.00033 20.4 8.8 0.00056 19.6 8.8 1.3 1 0 0 1 1 1 1 Spt20 family Pkinase_Tyr PF07714.17 CDJ69398.1 - 0.00041 19.7 0.1 0.00099 18.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Med15 PF09606.10 CDJ69398.1 - 0.0028 16.4 8.5 0.0028 16.4 8.5 2.1 3 0 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF533 PF04391.12 CDJ69398.1 - 0.0077 15.8 2.9 0.0077 15.8 2.9 1.5 2 0 0 2 2 1 1 Protein of unknown function (DUF533) Zn_peptidase PF04228.13 CDJ69398.1 - 0.034 13.6 3.1 0.054 12.9 3.1 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase AbrB PF05145.12 CDJ69398.1 - 0.099 11.6 0.2 0.17 10.8 0.2 1.3 1 0 0 1 1 1 0 Transition state regulatory protein AbrB DUF4834 PF16118.5 CDJ69398.1 - 0.11 13.4 0.7 0.11 13.4 0.7 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) Activator_LAG-3 PF11498.8 CDJ69398.1 - 0.12 11.4 17.4 0.015 14.3 13.5 1.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 TMEM164 PF14808.6 CDJ69398.1 - 0.19 11.0 0.1 0.28 10.5 0.1 1.1 1 0 0 1 1 1 0 TMEM164 family Pyridoxal_deC PF00282.19 CDJ69398.1 - 0.25 10.0 1.8 0.35 9.5 1.8 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain TMEM51 PF15345.6 CDJ69398.1 - 8.2 6.2 7.9 20 5.0 7.9 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 Orf78 PF06024.12 CDJ69399.1 - 4.8 7.5 6.1 5.2 7.4 6.1 1.1 1 0 0 1 1 1 0 Orf78 (ac78) DUF3464 PF11947.8 CDJ69399.1 - 5.9 6.6 8.5 6 6.6 8.5 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Presenilin PF01080.17 CDJ69399.1 - 7.3 5.2 9.3 6.6 5.4 9.3 1.0 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.14 CDJ69399.1 - 8.6 6.1 8.6 8 6.2 8.6 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus tRNA-synt_1g PF09334.11 CDJ69400.1 - 3.7e-05 22.7 0.2 3.7e-05 22.7 0.2 3.7 3 1 0 3 3 3 2 tRNA synthetases class I (M) DUF2722 PF10846.8 CDJ69400.1 - 0.00099 18.2 4.8 0.00099 18.2 4.8 6.2 4 2 2 6 6 6 2 Protein of unknown function (DUF2722) ANAPC_CDC26 PF10471.9 CDJ69401.1 - 0.0059 17.4 15.0 0.0059 17.4 15.0 39.7 9 4 23 32 32 32 2 Anaphase-promoting complex APC subunit CDC26 NFACT-R_1 PF05670.13 CDJ69402.1 - 1.1e-39 135.5 0.0 1.8e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 CDJ69402.1 - 0.011 15.9 1.1 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 NFACT protein RNA binding domain FAM199X PF15814.5 CDJ69402.1 - 4.8 6.1 6.2 5.7 5.9 6.2 1.2 1 0 0 1 1 1 0 Protein family FAM199X Rgp1 PF08737.10 CDJ69404.1 - 3.6e-07 29.7 10.5 3.6e-07 29.7 10.5 4.6 4 2 0 4 4 4 1 Rgp1 SR-25 PF10500.9 CDJ69404.1 - 0.0031 17.2 11.9 0.0031 17.2 11.9 9.0 7 1 1 8 8 8 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ69404.1 - 0.0045 16.6 3.0 0.0045 16.6 3.0 7.7 6 2 1 7 7 7 2 Spt20 family RskA PF10099.9 CDJ69404.1 - 0.0054 17.0 3.3 0.0054 17.0 3.3 11.6 3 2 4 8 8 8 1 Anti-sigma-K factor rskA Arrestin_N PF00339.29 CDJ69404.1 - 0.03 14.4 2.8 2.7 8.0 0.1 3.1 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain PseudoU_synth_1 PF01416.20 CDJ69406.1 - 3.8e-06 27.3 3.0 0.0012 19.3 0.0 3.7 3 1 0 3 3 3 2 tRNA pseudouridine synthase DUF2347 PF09804.9 CDJ69406.1 - 8.5 5.9 18.7 2.6 7.6 11.6 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) AAA PF00004.29 CDJ69407.1 - 2.8e-13 50.4 0.0 1.1e-12 48.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TFIIA PF03153.13 CDJ69407.1 - 3.1e-05 24.1 90.7 0.003 17.6 53.8 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit FtsH_ext PF06480.15 CDJ69407.1 - 0.0095 16.3 0.0 0.034 14.5 0.0 1.9 2 0 0 2 2 2 1 FtsH Extracellular RskA PF10099.9 CDJ69407.1 - 0.01 16.2 24.0 0.01 16.2 24.0 6.0 3 2 2 5 5 5 0 Anti-sigma-K factor rskA Macoilin PF09726.9 CDJ69407.1 - 0.011 14.4 35.1 0.028 13.0 2.4 2.4 2 0 0 2 2 2 0 Macoilin family Exonuc_VII_L PF02601.15 CDJ69407.1 - 3.3 7.2 46.0 1.8 8.1 10.4 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Asp_protease_2 PF13650.6 CDJ69408.1 - 1.1e-09 38.8 0.0 3.7e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 CDJ69408.1 - 1.7e-09 37.5 0.0 2.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ69408.1 - 2.6e-08 34.3 0.0 5.3e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ69408.1 - 0.00081 19.7 0.0 0.0036 17.6 0.0 2.1 2 1 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ69408.1 - 0.0016 18.3 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 CDJ69408.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RT_RNaseH PF17917.1 CDJ69409.1 - 6.1e-29 100.4 0.0 8.2e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ69409.1 - 2.6e-28 98.0 0.0 3.9e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FAM92 PF06730.11 CDJ69409.1 - 0.03 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 FAM92 protein Scramblase PF03803.15 CDJ69409.1 - 0.23 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Scramblase rve PF00665.26 CDJ69410.1 - 3.4e-08 33.7 0.1 3.9e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Integrase core domain VRR_NUC PF08774.11 CDJ69411.1 - 7.8e-16 58.1 11.2 5.3e-13 49.0 8.1 4.2 2 1 0 2 2 2 1 VRR-NUC domain SDA1 PF05285.12 CDJ69412.1 - 0.11 11.9 11.4 0.14 11.6 11.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CDJ69412.1 - 7.1 4.7 10.8 8.3 4.5 10.8 1.0 1 0 0 1 1 1 0 Nop14-like family Methyltr_RsmB-F PF01189.17 CDJ69414.1 - 0.00058 19.5 0.6 0.00058 19.5 0.6 1.6 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Spt20 PF12090.8 CDJ69414.1 - 0.0042 16.7 14.7 0.0042 16.7 14.7 3.1 2 1 0 2 2 2 1 Spt20 family DUF677 PF05055.12 CDJ69414.1 - 0.87 8.4 6.0 1.4 7.7 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Pkinase PF00069.25 CDJ69416.1 - 5.8e-11 42.3 1.7 7.6e-09 35.3 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain Na_trans_cytopl PF11933.8 CDJ69416.1 - 4.5 7.0 14.6 0.04 13.7 4.5 2.5 2 0 0 2 2 2 0 Cytoplasmic domain of voltage-gated Na+ ion channel DUF4471 PF14740.6 CDJ69416.1 - 6.7 5.8 12.7 6.7 5.8 8.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Pox_Ag35 PF03286.14 CDJ69416.1 - 8.7 6.1 17.9 0.99 9.2 10.3 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein cEGF PF12662.7 CDJ69418.1 - 1.1e-20 73.2 18.2 5.2e-08 32.7 0.1 4.5 4 0 0 4 4 4 4 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDJ69418.1 - 5.5e-20 71.4 31.6 4.4e-11 42.9 3.9 4.2 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CDJ69418.1 - 7.4e-15 54.9 23.0 4.7e-06 26.7 2.9 3.7 3 0 0 3 3 3 3 Calcium-binding EGF domain EGF PF00008.27 CDJ69418.1 - 8.6e-10 38.7 26.9 0.00088 19.5 2.7 4.3 4 0 0 4 4 4 3 EGF-like domain EGF_3 PF12947.7 CDJ69418.1 - 3.9e-06 26.9 16.7 0.0072 16.5 2.2 3.5 3 0 0 3 3 3 3 EGF domain hEGF PF12661.7 CDJ69418.1 - 5.5e-05 23.6 28.2 0.034 14.8 2.9 4.4 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CDJ69418.1 - 0.069 13.2 7.3 1.5 9.0 0.2 3.4 3 0 0 3 3 3 0 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CDJ69418.1 - 1.5 9.2 11.5 7.8 6.9 0.7 3.6 3 0 0 3 3 3 0 Pvs28 EGF domain IMUP PF15761.5 CDJ69418.1 - 2.2 9.0 34.5 1.7 9.4 9.6 4.0 3 0 0 3 3 3 0 Immortalisation up-regulated protein Med15 PF09606.10 CDJ69419.1 - 0.42 9.2 49.7 0.47 9.1 49.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 CDJ69419.1 - 0.61 8.8 26.8 0.83 8.4 26.8 1.3 1 0 0 1 1 1 0 Presenilin SARAF PF06682.12 CDJ69419.1 - 0.85 9.2 18.9 1.1 8.9 18.9 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4045 PF13254.6 CDJ69419.1 - 0.96 9.0 25.3 1.3 8.6 25.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Lin-8 PF03353.15 CDJ69419.1 - 1.3 8.5 30.1 1.8 8.0 30.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RIFIN PF02009.16 CDJ69419.1 - 1.5 8.6 20.9 2.2 8.1 20.9 1.2 1 0 0 1 1 1 0 Rifin Hid1 PF12722.7 CDJ69419.1 - 1.8 6.6 23.3 2 6.4 23.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.6 CDJ69419.1 - 7.7 5.2 20.0 9.1 5.0 20.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hamartin PF04388.12 CDJ69419.1 - 9.2 4.8 21.4 11 4.6 21.4 1.0 1 0 0 1 1 1 0 Hamartin protein GREB1 PF15782.5 CDJ69419.1 - 9.8 3.1 25.8 11 2.9 25.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1764 PF08576.10 CDJ69420.1 - 0.038 14.9 3.4 0.038 14.9 3.4 4.5 3 2 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) DNA_pol_B_palm PF14792.6 CDJ69421.1 - 1.7e-13 50.8 0.5 2.1e-11 44.1 0.0 3.6 4 0 0 4 4 4 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 CDJ69421.1 - 5.1e-12 45.8 0.0 3.5e-11 43.1 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 CDJ69421.1 - 7.6e-09 35.8 1.8 7.6e-08 32.6 0.0 3.2 3 0 0 3 3 3 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CDJ69421.1 - 5.3e-05 23.0 0.4 0.0004 20.2 0.8 2.3 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda SUIM_assoc PF16619.5 CDJ69421.1 - 5.9e-05 23.1 36.0 0.061 13.4 0.0 5.5 4 1 1 5 5 5 3 Unstructured region C-term to UIM in Ataxin3 HHH PF00633.23 CDJ69421.1 - 0.0077 16.1 0.0 2.2 8.3 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 CDJ69421.1 - 0.12 13.0 1.1 0.28 11.8 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain DEAD PF00270.29 CDJ69422.1 - 4.4e-15 55.9 0.5 4.4e-15 55.9 0.5 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ69422.1 - 0.00046 20.2 0.1 0.00073 19.6 0.1 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDJ69422.1 - 0.00056 19.7 0.1 0.00056 19.7 0.1 1.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDJ69422.1 - 0.024 14.9 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 CDJ69422.1 - 0.041 13.7 0.3 0.067 13.1 0.0 1.5 2 0 0 2 2 2 0 Helicase DUF4667 PF15700.5 CDJ69423.1 - 0.26 11.4 0.0 0.26 11.4 0.0 22.7 9 7 7 18 18 18 0 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ69424.1 - 0.0046 16.6 16.7 0.0052 16.4 16.7 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Bac_transf PF02397.16 CDJ69424.1 - 0.05 13.2 1.1 0.054 13.1 1.1 1.1 1 0 0 1 1 1 0 Bacterial sugar transferase DUF3367 PF11847.8 CDJ69424.1 - 0.29 9.0 2.7 0.3 8.9 2.7 1.0 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase ANAPC_CDC26 PF10471.9 CDJ69424.1 - 0.52 11.2 25.8 0.75 10.7 25.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 MPM1 PF17234.2 CDJ69424.1 - 0.6 10.4 9.7 0.66 10.2 9.7 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Lin-8 PF03353.15 CDJ69424.1 - 0.78 9.2 14.3 0.82 9.2 14.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDK2AP PF09806.9 CDJ69424.1 - 1.3 9.1 17.1 1.4 8.9 17.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein BAT2_N PF07001.11 CDJ69424.1 - 1.3 9.4 18.8 1.4 9.4 18.8 1.0 1 0 0 1 1 1 0 BAT2 N-terminus Spt20 PF12090.8 CDJ69424.1 - 1.8 8.2 29.1 2.1 7.9 29.1 1.1 1 0 0 1 1 1 0 Spt20 family CCDC106 PF15794.5 CDJ69424.1 - 2.2 7.9 15.1 2.4 7.8 15.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 IMUP PF15761.5 CDJ69424.1 - 2.2 9.0 14.5 2.6 8.8 14.5 1.3 1 1 0 1 1 1 0 Immortalisation up-regulated protein DEAD_assoc PF08494.11 CDJ69424.1 - 3.2 7.5 7.4 4.4 7.1 7.4 1.2 1 0 0 1 1 1 0 DEAD/H associated DUF4667 PF15700.5 CDJ69424.1 - 3.3 7.7 17.4 3.8 7.6 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) DUF1635 PF07795.11 CDJ69424.1 - 5.6 6.8 18.6 6.8 6.5 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) GREB1 PF15782.5 CDJ69424.1 - 6 3.8 16.2 6.2 3.8 16.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RskA PF10099.9 CDJ69425.1 - 0.012 15.9 4.2 0.012 15.9 4.2 7.7 2 2 1 4 4 4 0 Anti-sigma-K factor rskA CD20 PF04103.15 CDJ69425.1 - 3.9 7.6 16.5 9 6.4 4.2 3.7 3 1 1 4 4 4 0 CD20-like family SMC_hinge PF06470.13 CDJ69426.1 - 1.8e-10 41.1 4.1 4.7e-10 39.8 0.0 2.9 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain TMPIT PF07851.13 CDJ69426.1 - 0.0096 15.2 6.0 0.0096 15.2 6.0 2.8 1 1 2 3 3 3 1 TMPIT-like protein HpaB_N PF11794.8 CDJ69426.1 - 0.18 11.5 10.7 1.4 8.5 2.1 2.1 1 1 1 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal FliJ PF02050.16 CDJ69426.1 - 0.18 12.0 76.6 3.3 8.0 23.7 3.3 1 1 2 3 3 3 0 Flagellar FliJ protein MAD PF05557.13 CDJ69426.1 - 1.6 7.0 53.9 2.1 6.6 53.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Ribosomal_L12 PF00542.19 CDJ69426.1 - 3.8 7.9 9.0 14 6.1 1.8 3.2 1 1 1 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain SPX PF03105.19 CDJ69426.1 - 4 7.2 19.7 6.8 6.5 19.7 1.4 1 0 0 1 1 1 0 SPX domain TMF_TATA_bd PF12325.8 CDJ69426.1 - 7.4 6.8 53.3 0.9 9.8 18.4 3.5 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding SH2_2 PF14633.6 CDJ69427.1 - 1.4e-08 34.4 0.0 1.4e-08 34.4 0.0 4.6 5 1 0 5 5 5 1 SH2 domain HHH_7 PF14635.6 CDJ69427.1 - 1.4e-08 35.0 0.0 4.7e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif SR-25 PF10500.9 CDJ69427.1 - 0.00046 19.9 15.6 0.00046 19.9 15.6 9.4 10 2 0 10 10 10 3 Nuclear RNA-splicing-associated protein HTH_44 PF14641.6 CDJ69427.1 - 0.00046 20.6 0.1 0.0027 18.1 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 RT_RNaseH PF17917.1 CDJ69428.1 - 1.2e-28 99.4 0.1 1.9e-28 98.8 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ69428.1 - 1.5e-27 95.5 0.0 2.6e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FAM92 PF06730.11 CDJ69428.1 - 0.09 12.2 0.0 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 FAM92 protein zf-CCCH PF00642.24 CDJ69429.1 - 1.2e-09 37.8 12.2 8.4e-07 28.8 1.0 3.7 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ69429.1 - 2.6e-06 27.3 16.3 0.00041 20.3 1.1 3.5 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 CDJ69429.1 - 0.13 12.9 0.8 0.13 12.9 0.8 3.1 1 1 2 3 3 3 0 Torus domain zf-CCCH_4 PF18044.1 CDJ69429.1 - 0.46 10.3 16.8 0.37 10.6 1.1 4.0 3 2 0 3 3 3 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CDJ69429.1 - 0.5 10.9 11.3 7.6 7.2 1.3 3.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CDJ69429.1 - 1.1 9.5 8.6 2.8 8.2 3.2 2.3 1 1 1 2 2 2 0 Zinc-finger containing family TFIIA PF03153.13 CDJ69430.1 - 0.0021 18.1 22.2 0.0026 17.8 22.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Exo_endo_phos PF03372.23 CDJ69431.1 - 0.00013 21.6 0.0 0.00049 19.7 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spt20 PF12090.8 CDJ69431.1 - 6.3 6.3 36.5 0.45 10.1 8.7 2.5 2 0 0 2 2 2 0 Spt20 family CDP-OH_P_transf PF01066.21 CDJ69432.1 - 2e-11 44.5 0.0 2e-11 44.5 0.0 3.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Presenilin PF01080.17 CDJ69434.1 - 0.0001 21.2 14.9 0.00014 20.8 14.9 1.3 1 0 0 1 1 1 1 Presenilin DUF5308 PF17233.2 CDJ69434.1 - 0.0038 17.5 4.3 0.0038 17.5 4.3 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5308) Eapp_C PF10238.9 CDJ69434.1 - 0.0043 17.1 4.7 0.0043 17.1 4.7 2.3 2 1 0 2 2 2 1 E2F-associated phosphoprotein FAM176 PF14851.6 CDJ69434.1 - 0.02 14.5 5.4 0.02 14.5 5.4 2.2 2 0 0 2 2 2 0 FAM176 family RNA_pol_Rpc4 PF05132.14 CDJ69434.1 - 0.023 15.1 7.1 0.023 15.1 7.1 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 TRAP_alpha PF03896.16 CDJ69434.1 - 0.037 13.2 6.6 0.021 14.0 3.5 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SART-1 PF03343.13 CDJ69434.1 - 0.13 10.7 25.4 0.21 10.1 25.4 1.2 1 0 0 1 1 1 0 SART-1 family GramPos_pilinD1 PF16555.5 CDJ69434.1 - 0.16 12.1 12.1 0.022 14.9 6.0 2.1 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain TMEM144 PF07857.12 CDJ69434.1 - 0.2 10.6 0.1 0.29 10.1 0.1 1.3 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters RXT2_N PF08595.11 CDJ69434.1 - 0.3 11.1 11.6 0.068 13.2 6.9 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal EMC3_TMCO1 PF01956.16 CDJ69434.1 - 1.2 8.9 17.6 0.03 14.1 6.3 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like CCDC53 PF10152.9 CDJ69434.1 - 1.2 9.5 26.9 0.27 11.7 13.8 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Spore_coat_CotO PF14153.6 CDJ69434.1 - 2.3 8.1 33.1 0.57 10.1 20.2 2.3 2 0 0 2 2 2 0 Spore coat protein CotO CAC1F_C PF16885.5 CDJ69434.1 - 5 6.7 16.9 7.2 6.2 16.9 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term ABC2_membrane_2 PF12679.7 CDJ69434.1 - 5 6.3 8.9 0.26 10.5 2.4 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein ETRAMP PF09716.10 CDJ69435.1 - 0.028 14.5 0.1 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TFIIA PF03153.13 CDJ69436.1 - 0.00026 21.1 48.7 0.00033 20.8 48.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 CDJ69436.1 - 0.014 15.9 9.5 0.015 15.8 9.5 1.2 1 0 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.12 CDJ69436.1 - 0.11 11.4 20.5 0.13 11.2 20.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GREB1 PF15782.5 CDJ69436.1 - 0.12 9.5 23.5 0.15 9.2 23.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SID-1_RNA_chan PF13965.6 CDJ69436.1 - 0.48 8.8 3.9 0.54 8.6 3.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 CDJ69436.1 - 0.5 8.6 31.9 0.67 8.2 31.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.8 CDJ69436.1 - 0.64 8.9 47.4 0.99 8.3 47.4 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SLC12 PF03522.15 CDJ69436.1 - 0.82 8.6 14.4 0.94 8.4 14.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 CDJ69436.1 - 1.1 7.9 12.6 1.3 7.7 12.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2232 PF09991.9 CDJ69436.1 - 2 7.5 7.1 2.9 7.0 7.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF572 PF04502.13 CDJ69436.1 - 2.5 7.7 23.0 3.2 7.3 23.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MMR1 PF08505.10 CDJ69436.1 - 2.6 8.3 20.4 4.2 7.6 19.6 1.8 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Serinc PF03348.15 CDJ69436.1 - 3.4 6.5 10.4 4.3 6.2 10.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) ALMT PF11744.8 CDJ69436.1 - 3.5 6.3 11.1 4.2 6.1 11.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SpoIIP PF07454.11 CDJ69436.1 - 4.2 6.8 19.9 6.6 6.1 19.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Utp14 PF04615.13 CDJ69439.1 - 1.2e-05 24.1 0.7 1.2e-05 24.1 0.7 4.9 2 2 1 4 4 4 1 Utp14 protein SUIM_assoc PF16619.5 CDJ69441.1 - 0.12 12.4 15.9 0.23 11.5 10.2 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3678 PF12435.8 CDJ69441.1 - 1.5 8.2 7.2 6.6 6.2 0.3 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) DUF4667 PF15700.5 CDJ69442.1 - 1.7e-05 25.0 5.0 0.021 15.0 1.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) DUF4834 PF16118.5 CDJ69442.1 - 0.00057 20.8 11.6 0.00057 20.8 11.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) CBP_BcsG PF11658.8 CDJ69442.1 - 0.0044 15.5 8.7 0.0055 15.2 8.7 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG SpoIIP PF07454.11 CDJ69442.1 - 0.0057 16.1 8.4 0.0086 15.6 8.4 1.3 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) YfhO PF09586.10 CDJ69442.1 - 0.016 13.5 10.9 0.019 13.2 10.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SID-1_RNA_chan PF13965.6 CDJ69442.1 - 0.018 13.4 2.8 0.19 10.1 4.9 1.5 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 IMUP PF15761.5 CDJ69442.1 - 0.02 15.6 6.2 0.02 15.6 6.2 2.1 2 0 0 2 2 1 0 Immortalisation up-regulated protein DUF1645 PF07816.11 CDJ69442.1 - 0.027 15.1 9.3 0.41 11.2 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Serinc PF03348.15 CDJ69442.1 - 0.13 11.1 4.3 0.2 10.6 4.3 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Connexin PF00029.19 CDJ69442.1 - 0.24 11.1 9.7 0.43 10.3 9.7 1.4 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.19 CDJ69442.1 - 0.35 8.7 19.6 0.45 8.4 19.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 CDJ69442.1 - 0.57 9.8 7.6 1.2 8.7 6.7 1.9 2 0 0 2 2 2 0 FAM176 family Folliculin PF11704.8 CDJ69442.1 - 0.62 9.9 14.5 4 7.3 14.6 1.9 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DcuA_DcuB PF03605.14 CDJ69442.1 - 0.74 8.6 6.2 1.1 8.0 6.2 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter PigN PF04987.14 CDJ69442.1 - 1.4 7.7 8.7 2.4 6.9 8.7 1.4 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) FPN1 PF06963.12 CDJ69442.1 - 1.4 7.4 7.6 2.3 6.7 7.6 1.4 1 0 0 1 1 1 0 Ferroportin1 (FPN1) OATP PF03137.20 CDJ69442.1 - 2 6.6 7.7 1 7.6 5.9 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2828 PF11443.8 CDJ69442.1 - 2.3 6.2 14.5 3 5.8 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CLN3 PF02487.17 CDJ69442.1 - 2.4 7.1 12.1 3.6 6.5 12.1 1.2 1 0 0 1 1 1 0 CLN3 protein O-antigen_lig PF13425.6 CDJ69442.1 - 4.5 6.0 5.5 5.9 5.6 5.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Pap_E4 PF02711.14 CDJ69442.1 - 4.6 8.3 19.3 0.89 10.6 1.3 2.3 2 0 0 2 2 2 0 E4 protein Presenilin PF01080.17 CDJ69442.1 - 6.3 5.4 20.7 13 4.4 20.7 1.6 1 1 0 1 1 1 0 Presenilin ALMT PF11744.8 CDJ69442.1 - 6.6 5.4 9.9 9.4 4.9 9.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1980 PF09323.10 CDJ69442.1 - 6.7 6.6 15.2 0.12 12.2 8.4 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF1980) Peptidase_S49_N PF08496.10 CDJ69442.1 - 9.6 6.3 16.3 14 5.7 16.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ephrin_rec_like PF07699.13 CDJ69443.1 - 3.6e-09 36.3 43.9 4.8e-08 32.6 5.7 6.4 4 1 1 5 5 5 3 Putative ephrin-receptor like DUF4667 PF15700.5 CDJ69443.1 - 9.2e-06 25.9 29.4 0.07 13.2 0.0 4.4 4 0 0 4 4 4 4 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ69443.1 - 0.71 9.4 94.0 0.014 15.0 13.0 5.5 5 0 0 5 5 5 0 Nuclear RNA-splicing-associated protein TACI-CRD2 PF09305.10 CDJ69443.1 - 1.8 8.7 8.1 0.13 12.3 1.7 2.6 2 0 0 2 2 2 0 TACI, cysteine-rich domain DUF1645 PF07816.11 CDJ69443.1 - 3.5 8.2 49.5 0.65 10.5 2.1 4.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1645) ubiquitin PF00240.23 CDJ69445.1 - 7e-68 224.3 4.2 2.1e-34 117.1 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CDJ69445.1 - 4.4e-33 112.9 5.0 2.7e-16 59.2 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ69445.1 - 1.3e-13 51.2 0.7 4e-05 24.0 0.1 3.3 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ69445.1 - 1.4e-08 34.6 0.2 0.0056 16.6 0.0 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ69445.1 - 3.1e-07 30.5 0.2 0.027 14.6 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CDJ69445.1 - 4.4e-07 30.2 0.5 0.017 15.5 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 CDJ69445.1 - 3.9e-06 27.4 0.0 0.12 13.0 0.0 2.1 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CDJ69445.1 - 0.00014 21.8 6.8 8.2 6.5 0.0 4.0 4 0 0 4 4 4 3 Ubiquitin-like domain DUF2870 PF11069.8 CDJ69445.1 - 0.018 15.4 0.1 10 6.6 0.0 2.8 2 2 2 4 4 4 0 Protein of unknown function (DUF2870) Sde2_N_Ubi PF13019.6 CDJ69445.1 - 0.045 13.6 0.0 0.67 9.8 0.0 2.0 1 1 1 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain TmoB PF06234.12 CDJ69445.1 - 0.049 13.7 0.4 16 5.7 0.0 2.7 2 2 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) FERM_f0 PF16511.5 CDJ69445.1 - 0.057 13.7 2.2 29 5.1 0.2 3.6 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM FlgD_ig PF13860.6 CDJ69445.1 - 0.097 12.5 0.6 19 5.2 0.1 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain TraG_N PF07916.11 CDJ69446.1 - 0.00084 18.3 6.6 0.00084 18.3 6.6 6.1 6 3 0 6 6 6 1 TraG-like protein, N-terminal region TIM PF00121.18 CDJ69447.1 - 4.5e-51 173.6 0.1 1.3e-32 113.1 0.0 2.0 1 1 1 2 2 2 2 Triosephosphate isomerase LD_cluster2 PF18163.1 CDJ69447.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 2 0 0 2 2 2 0 SLOG cluster2 Not1 PF04054.15 CDJ69448.1 - 0.012 14.5 0.1 0.012 14.5 0.1 2.0 2 0 0 2 2 2 0 CCR4-Not complex component, Not1 Rpp20 PF12328.8 CDJ69448.1 - 0.025 14.5 6.9 0.028 14.4 6.9 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF4834 PF16118.5 CDJ69448.1 - 0.099 13.6 7.6 0.098 13.6 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CDH1_2_SANT_HL1 PF18375.1 CDJ69448.1 - 0.12 13.1 3.1 0.13 12.9 3.1 1.1 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 ABC2_membrane_2 PF12679.7 CDJ69448.1 - 0.46 9.7 3.1 0.46 9.7 3.1 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Coilin_N PF15862.5 CDJ69448.1 - 0.61 9.9 10.2 0.59 9.9 10.2 1.1 1 0 0 1 1 1 0 Coilin N-terminus Hid1 PF12722.7 CDJ69448.1 - 0.66 8.0 7.8 0.65 8.1 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TMEM208_SND2 PF05620.11 CDJ69448.1 - 0.66 9.7 4.9 0.65 9.8 4.9 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 EIIBC-GUT_N PF03612.14 CDJ69448.1 - 1.3 8.7 7.5 1.3 8.7 7.5 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Spt20 PF12090.8 CDJ69448.1 - 1.5 8.3 32.6 1.7 8.2 32.6 1.0 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 CDJ69448.1 - 1.7 9.3 15.2 1.8 9.2 15.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 CDJ69448.1 - 2.7 6.8 26.6 2.9 6.7 26.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ69448.1 - 2.9 6.5 9.0 2.8 6.6 9.0 1.0 1 0 0 1 1 1 0 Presenilin PigN PF04987.14 CDJ69448.1 - 3 6.6 4.0 2.6 6.8 4.0 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) CLN3 PF02487.17 CDJ69448.1 - 3.8 6.5 4.8 3.5 6.6 4.8 1.0 1 0 0 1 1 1 0 CLN3 protein Zip PF02535.22 CDJ69448.1 - 4 6.6 4.3 4.1 6.5 4.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter TERB2 PF15101.6 CDJ69448.1 - 4.9 7.1 14.9 4.8 7.2 14.9 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 WASH-7_C PF14746.6 CDJ69448.1 - 4.9 6.8 11.7 6.1 6.5 11.7 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal TFIIA PF03153.13 CDJ69448.1 - 5.3 6.9 26.5 5.3 6.9 26.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3464 PF11947.8 CDJ69448.1 - 6.9 6.4 9.0 6.6 6.5 9.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Suf PF05843.14 CDJ69448.1 - 8.3 6.3 14.9 9.3 6.1 14.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.10 CDJ69448.1 - 8.8 4.9 26.2 8.7 4.9 26.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LPD15 PF18828.1 CDJ69449.1 - 0.12 12.3 4.5 0.24 11.3 1.9 2.0 2 0 0 2 2 2 0 Large polyvalent-protein-associated domain 15 Nop53 PF07767.11 CDJ69449.1 - 0.21 10.9 21.3 0.28 10.5 21.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Herpes_LAMP2 PF06126.11 CDJ69449.1 - 0.38 9.3 0.8 0.4 9.2 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 DUF3474 PF11960.8 CDJ69449.1 - 3 8.0 4.6 2 8.6 1.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3474) STAC2_u1 PF16664.5 CDJ69449.1 - 4.6 7.7 16.9 1.4 9.4 5.8 2.1 1 1 1 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Serinc PF03348.15 CDJ69449.1 - 6.5 5.6 8.8 8.4 5.2 8.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) MT PF12777.7 CDJ69450.1 - 1.4e-44 152.6 10.7 4e-44 151.0 10.7 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 CDJ69450.1 - 7.9e-35 120.0 2.4 3.3e-19 68.9 6.1 5.1 4 1 1 5 5 4 2 ATP-binding dynein motor region AAA_8 PF12780.7 CDJ69450.1 - 6.8e-34 117.4 0.0 6.4e-22 78.1 0.0 3.5 2 1 0 2 2 2 2 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CDJ69450.1 - 2.2e-30 106.0 0.0 6.5e-29 101.1 0.0 4.6 5 1 0 5 5 5 2 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 CDJ69450.1 - 9.4e-23 80.6 0.1 7.8e-22 77.6 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 CDJ69450.1 - 3.6e-15 56.0 0.0 7.3e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_lid_11 PF18198.1 CDJ69450.1 - 3e-14 53.2 0.0 1.3e-13 51.1 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Spt20 PF12090.8 CDJ69450.1 - 0.00029 20.5 13.8 0.00029 20.5 13.8 6.7 4 1 0 4 4 2 1 Spt20 family DUF1464 PF07318.12 CDJ69450.1 - 0.0067 15.6 0.2 0.016 14.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1464) RskA PF10099.9 CDJ69450.1 - 0.1 12.9 0.0 0.1 12.9 0.0 10.2 7 4 3 10 10 6 0 Anti-sigma-K factor rskA Gemini_AL3 PF01407.17 CDJ69450.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Geminivirus AL3 protein Autophagy_act_C PF03987.15 CDJ69451.1 - 2.2e-21 76.2 0.3 3.5e-21 75.5 0.3 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CDJ69451.1 - 5.5e-13 48.2 2.4 9e-13 47.5 2.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF4148 PF13663.6 CDJ69452.1 - 0.016 15.4 5.1 0.73 10.1 5.1 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) TFIIA PF03153.13 CDJ69454.1 - 1.1e-05 25.7 85.3 0.014 15.4 26.0 3.5 3 0 0 3 3 3 3 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.9 CDJ69454.1 - 0.00036 19.5 9.2 0.00036 19.5 9.2 3.2 3 0 0 3 3 3 1 Mitochondrial inner membrane protein SARAF PF06682.12 CDJ69454.1 - 0.023 14.3 0.0 0.023 14.3 0.0 3.5 2 1 1 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Presenilin PF01080.17 CDJ69454.1 - 0.035 12.9 36.1 0.43 9.3 4.6 3.1 3 0 0 3 3 3 0 Presenilin DGF-1_C PF11040.8 CDJ69454.1 - 0.28 11.2 9.5 0.51 10.4 3.3 3.5 2 1 1 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SAPS PF04499.15 CDJ69454.1 - 0.82 8.4 18.0 0.56 8.9 7.0 2.5 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein Lin-8 PF03353.15 CDJ69454.1 - 1.4 8.5 42.7 0.18 11.3 14.7 3.2 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist DUF2076 PF09849.9 CDJ69454.1 - 2.3 8.2 86.8 0.99 9.4 25.1 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) CCSAP PF15748.5 CDJ69454.1 - 6.4 6.9 42.7 1.7 8.8 6.0 3.2 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated EF-hand_7 PF13499.6 CDJ69457.1 - 0.011 16.2 0.0 0.03 14.8 0.0 1.7 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 CDJ69457.1 - 0.14 12.1 0.0 0.76 9.9 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain eRF1_1 PF03463.15 CDJ69457.1 - 0.25 11.4 0.2 0.25 11.4 0.2 1.8 2 1 0 2 2 2 0 eRF1 domain 1 DUF755 PF05501.11 CDJ69457.1 - 1.6 9.0 47.3 0.062 13.6 8.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF755) RIFIN PF02009.16 CDJ69457.1 - 2 8.3 10.4 2.7 7.8 10.4 1.2 1 0 0 1 1 1 0 Rifin Pkinase PF00069.25 CDJ69458.1 - 1e-45 156.1 0.0 5.6e-44 150.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ69458.1 - 2.6e-18 66.2 0.0 3.4e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ69458.1 - 0.00069 18.5 0.0 0.00093 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ69458.1 - 0.0025 17.2 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ69458.1 - 0.047 13.6 11.2 4.1 7.2 11.2 3.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ69458.1 - 0.056 12.8 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Kinase-like TFIIF_alpha PF05793.12 CDJ69459.1 - 1.8 7.1 26.0 0.024 13.3 18.8 1.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NAM-associated PF14303.6 CDJ69459.1 - 2 9.1 0.0 2 9.1 0.0 4.0 2 1 2 4 4 4 0 No apical meristem-associated C-terminal domain SRP-alpha_N PF04086.13 CDJ69459.1 - 3.4 7.5 31.5 0.4 10.6 26.0 1.9 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Helicase_C PF00271.31 CDJ69460.1 - 1.2e-23 83.6 0.0 1.7e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IFR3_antag PF14754.6 CDJ69461.1 - 0.04 13.1 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Papain-like auto-proteinase Plasmodium_Vir PF05795.11 CDJ69461.1 - 0.72 9.2 16.6 0.01 15.3 5.7 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein TFIIA PF03153.13 CDJ69461.1 - 2.6 8.0 44.7 0.23 11.4 30.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AMP-binding PF00501.28 CDJ69462.1 - 2.2e-71 240.7 0.0 3.2e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ69462.1 - 0.00025 21.9 0.0 0.00062 20.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_C26 PF07722.13 CDJ69463.1 - 5.1e-17 62.3 0.0 3.2e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase C26 GATase PF00117.28 CDJ69463.1 - 2.5e-12 47.0 0.0 1.4e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I MIF4G_like_2 PF09090.11 CDJ69464.1 - 3.7e-10 39.7 0.1 3.7e-10 39.7 0.1 2.0 1 1 0 2 2 2 1 MIF4G like Methyltransf_32 PF13679.6 CDJ69465.1 - 0.02 14.9 0.3 0.02 14.9 0.3 1.9 2 0 0 2 2 2 0 Methyltransferase domain TFIIA PF03153.13 CDJ69465.1 - 4 7.3 18.8 5.9 6.8 18.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Prominin PF05478.11 CDJ69466.1 - 0.00015 19.9 10.2 0.00015 19.9 10.2 1.9 2 0 0 2 2 2 1 Prominin Ran-binding PF05508.11 CDJ69466.1 - 0.011 14.7 3.5 0.011 14.7 3.5 3.1 3 0 0 3 3 3 0 RanGTP-binding protein UPF0147 PF03685.13 CDJ69466.1 - 0.052 13.6 0.1 0.3 11.2 0.1 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0147) Tropomyosin PF00261.20 CDJ69466.1 - 1.4 8.2 49.1 0.16 11.3 30.3 2.4 2 0 0 2 2 2 0 Tropomyosin DUF724 PF05266.14 CDJ69466.1 - 5.3 6.8 37.0 1.4 8.7 6.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF724) TFIIA PF03153.13 CDJ69467.1 - 0.033 14.2 8.1 0.036 14.1 8.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 CDJ69467.1 - 0.88 8.7 19.6 1.1 8.4 19.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ69467.1 - 2.5 8.3 19.6 0.32 11.3 14.3 1.8 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ69467.1 - 3.6 7.1 9.6 4.4 6.9 9.6 1.1 1 0 0 1 1 1 0 Spt20 family Ribosomal_60s PF00428.19 CDJ69467.1 - 4.6 7.9 19.0 0.37 11.4 11.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ69468.1 - 2.9 7.8 22.2 3.2 7.6 22.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ69469.1 - 0.0061 16.9 18.7 0.0061 16.9 18.7 7.3 3 2 3 6 6 6 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ69470.1 - 0.0081 15.8 1.5 0.0081 15.8 1.5 4.1 2 1 2 4 4 4 1 Spt20 family Phage_holin_4_2 PF04020.13 CDJ69471.1 - 0.0078 16.9 4.1 0.01 16.5 4.1 1.2 1 0 0 1 1 1 1 Mycobacterial 4 TMS phage holin, superfamily IV IspD PF01128.19 CDJ69472.1 - 4.9e-14 52.6 10.9 4.5e-12 46.2 5.6 3.4 3 0 0 3 3 3 2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF2722 PF10846.8 CDJ69472.1 - 0.0048 15.9 8.6 0.0048 15.9 8.6 5.2 5 0 0 5 5 5 2 Protein of unknown function (DUF2722) CCSAP PF15748.5 CDJ69472.1 - 0.0076 16.5 20.4 0.0076 16.5 20.4 2.6 3 0 0 3 3 3 1 Centriole, cilia and spindle-associated TAF1D PF15333.6 CDJ69472.1 - 8.1 6.1 14.8 7.9 6.2 5.5 2.5 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D DUF4614 PF15391.6 CDJ69473.1 - 2.8 7.9 11.5 0.092 12.7 4.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) TFIIA PF03153.13 CDJ69473.1 - 5.4 6.9 17.2 1.3 8.9 13.3 1.7 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 CDJ69473.1 - 6.2 6.9 11.7 15 5.6 11.7 1.6 1 1 0 1 1 1 0 Centriole, cilia and spindle-associated EF-hand_1 PF00036.32 CDJ69474.1 - 1.6e-40 133.6 10.2 1.2e-09 37.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ69474.1 - 7.6e-35 119.2 1.9 5.3e-17 62.0 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ69474.1 - 1e-32 111.8 10.5 8.2e-16 57.6 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDJ69474.1 - 7.1e-29 97.2 6.0 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ69474.1 - 4.9e-26 89.0 8.6 2.3e-06 26.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CDJ69474.1 - 4.3e-15 55.8 0.1 3.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDJ69474.1 - 2.3e-09 37.1 0.3 0.00039 20.3 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ69474.1 - 1.5e-07 31.7 0.1 0.017 15.4 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CDJ69474.1 - 3.3e-06 27.9 0.0 0.0009 20.1 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CDJ69474.1 - 2.8e-05 24.0 0.0 0.042 13.9 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 CDJ69474.1 - 0.00082 19.5 4.3 0.16 12.2 0.5 2.8 2 2 1 3 3 3 2 Dockerin type I domain Caleosin PF05042.13 CDJ69474.1 - 0.0017 18.3 0.2 0.52 10.2 0.0 3.1 1 1 2 3 3 3 1 Caleosin related protein DUF3349 PF11829.8 CDJ69474.1 - 0.0018 19.0 0.5 1.2 10.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.16 CDJ69474.1 - 0.0033 17.7 0.4 1.8 8.9 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF1103 PF06513.11 CDJ69474.1 - 0.0056 16.3 1.2 0.0067 16.1 1.2 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) EFhand_Ca_insen PF08726.10 CDJ69474.1 - 0.0068 16.5 0.4 0.042 13.9 0.0 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand YqeY PF09424.10 CDJ69474.1 - 0.012 15.6 0.2 0.15 12.1 0.1 2.0 1 1 1 2 2 2 0 Yqey-like protein SurA_N_2 PF13623.6 CDJ69474.1 - 0.015 15.1 0.4 0.85 9.5 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF853 PF05872.12 CDJ69474.1 - 0.026 13.2 0.2 0.7 8.4 0.1 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_14 PF17959.1 CDJ69474.1 - 0.035 14.4 0.1 9.2 6.7 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 CDJ69474.1 - 0.047 13.9 0.1 9.3 6.6 0.0 3.1 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein DUF5580 PF17743.1 CDJ69474.1 - 0.071 11.6 0.0 0.071 11.6 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Fe_hyd_lg_C PF02906.14 CDJ69474.1 - 0.072 12.7 0.6 0.23 11.1 0.6 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain TetR_C_7 PF14246.6 CDJ69474.1 - 0.095 12.7 0.0 6.3 6.9 0.0 2.3 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain SurA_N_3 PF13624.6 CDJ69474.1 - 0.1 12.4 0.2 0.44 10.3 0.0 1.9 1 1 1 2 2 2 0 SurA N-terminal domain dCache_2 PF08269.11 CDJ69474.1 - 0.1 11.7 0.0 7.7 5.6 0.0 2.1 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 CDJ69474.1 - 0.12 12.6 0.4 2 8.6 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Ribosomal_S10 PF00338.22 CDJ69475.1 - 7.5e-26 90.2 0.1 8.7e-26 90.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1922 PF09082.10 CDJ69475.1 - 0.02 15.2 0.1 0.048 14.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1922) Ribosomal_L35Ae PF01247.18 CDJ69476.1 - 3.2e-44 149.0 0.5 3.8e-44 148.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CDJ69476.1 - 0.055 13.7 0.1 5.3 7.3 0.0 2.3 2 0 0 2 2 2 0 RimM N-terminal domain OMPdecase PF00215.24 CDJ69477.1 - 6e-24 84.9 0.0 2.1e-23 83.1 0.0 1.7 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.14 CDJ69477.1 - 0.016 14.5 0.0 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG AP2 PF00847.20 CDJ69478.1 - 7.6e-19 67.7 11.0 9.1e-12 45.0 1.1 6.2 6 0 0 6 6 6 3 AP2 domain ACDC PF14733.6 CDJ69478.1 - 7e-09 35.9 0.1 2.4e-08 34.2 0.1 2.0 1 1 0 1 1 1 1 AP2-coincident C-terminal NPR3 PF03666.13 CDJ69478.1 - 1.3 7.7 12.5 0.089 11.6 0.1 2.6 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 PIP5K PF01504.18 CDJ69478.1 - 7.1 5.8 5.8 13 5.0 0.4 2.3 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase RLL PF10036.9 CDJ69479.1 - 3.5e-36 125.4 4.1 3.3e-24 86.1 2.0 2.1 2 0 0 2 2 2 2 RNA transcription, translation and transport factor protein PGM_PMM_I PF02878.16 CDJ69480.1 - 1.7e-07 31.0 0.1 3.5e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CDJ69480.1 - 4.3e-06 27.3 0.2 0.081 13.6 0.1 3.3 2 1 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF4518 PF15008.6 CDJ69480.1 - 0.2 10.8 2.1 0.28 10.3 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) DUF2722 PF10846.8 CDJ69480.1 - 0.3 10.0 6.1 0.49 9.3 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ69480.1 - 0.33 10.5 7.5 0.53 9.9 7.5 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ69480.1 - 1.2 9.2 13.0 1.2e+02 2.8 0.0 2.5 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AF-4 PF05110.13 CDJ69480.1 - 1.4 6.9 7.5 2.4 6.1 7.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TFIIA PF03153.13 CDJ69480.1 - 9.3 6.1 14.8 24 4.7 14.9 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ69481.1 - 0.32 10.8 11.3 0.39 10.5 11.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ69481.1 - 0.33 9.2 12.0 0.4 8.9 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 CDJ69481.1 - 0.91 8.4 5.1 1.3 7.9 5.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.7 CDJ69481.1 - 3.9 5.5 13.0 4.7 5.2 13.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.13 CDJ69481.1 - 4.4 7.2 31.9 6.2 6.7 31.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ69481.1 - 4.6 6.2 9.4 5.5 5.9 9.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 TFIIA PF03153.13 CDJ69482.1 - 0.0011 19.0 91.8 0.063 13.3 44.2 2.7 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ69482.1 - 0.14 11.2 24.8 0.27 10.2 4.3 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 CDJ69482.1 - 1.3 7.9 18.2 0.2 10.7 3.3 2.3 2 0 0 2 2 2 0 CLN3 protein Connexin PF00029.19 CDJ69482.1 - 2.8 7.6 17.7 0.088 12.6 2.3 2.2 2 0 0 2 2 2 0 Connexin SLC12 PF03522.15 CDJ69482.1 - 2.9 6.8 21.9 0.25 10.3 4.6 2.3 2 0 0 2 2 2 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ69482.1 - 7.1 4.9 8.1 4.1 5.7 0.5 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF4471 PF14740.6 CDJ69482.1 - 8.1 5.6 15.8 0.051 12.8 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) MDM10 PF12519.8 CDJ69484.1 - 0.05 12.5 17.3 0.058 12.3 17.3 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Mcm10 PF09332.11 CDJ69484.1 - 0.068 12.6 22.5 0.074 12.5 22.5 1.0 1 0 0 1 1 1 0 Mcm10 replication factor SelP_N PF04592.14 CDJ69484.1 - 0.075 12.4 30.2 0.089 12.2 30.2 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PIEZO PF15917.5 CDJ69484.1 - 0.12 11.8 24.1 0.15 11.5 24.1 1.1 1 0 0 1 1 1 0 Piezo CCSAP PF15748.5 CDJ69484.1 - 0.12 12.5 23.9 0.13 12.4 23.9 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 CDJ69484.1 - 0.13 11.0 28.1 0.15 10.8 28.1 1.0 1 0 0 1 1 1 0 Presenilin Gti1_Pac2 PF09729.9 CDJ69484.1 - 0.2 11.7 17.0 0.22 11.6 17.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family FAM76 PF16046.5 CDJ69484.1 - 0.24 10.7 21.8 0.29 10.4 21.8 1.1 1 0 0 1 1 1 0 FAM76 protein PAT1 PF09770.9 CDJ69484.1 - 0.25 9.6 37.7 0.27 9.5 37.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.6 CDJ69484.1 - 0.3 11.1 17.4 0.34 10.9 17.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4746 PF15928.5 CDJ69484.1 - 0.39 10.1 17.8 0.46 9.9 17.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MCM_bind PF09739.9 CDJ69484.1 - 0.42 9.0 21.6 0.5 8.8 21.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NST1 PF13945.6 CDJ69484.1 - 0.51 10.4 27.5 0.68 10.0 27.5 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator SpoIIP PF07454.11 CDJ69484.1 - 0.52 9.7 20.8 0.81 9.1 20.8 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Lin-8 PF03353.15 CDJ69484.1 - 0.53 9.8 25.3 0.58 9.7 25.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4050 PF13259.6 CDJ69484.1 - 0.58 10.5 20.8 0.69 10.2 20.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) NPR3 PF03666.13 CDJ69484.1 - 0.61 8.8 21.5 0.69 8.6 21.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1387 PF07139.11 CDJ69484.1 - 0.72 9.5 20.0 0.83 9.3 20.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Tim54 PF11711.8 CDJ69484.1 - 0.76 8.5 18.4 0.95 8.2 18.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GREB1 PF15782.5 CDJ69484.1 - 0.79 6.8 22.3 0.85 6.7 22.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer cwf18 PF08315.12 CDJ69484.1 - 0.93 10.2 20.5 1.2 9.8 20.5 1.1 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Membralin PF09746.9 CDJ69484.1 - 1.1 8.2 14.1 1.2 8.1 14.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein Hydin_ADK PF17213.3 CDJ69484.1 - 1.2 9.4 21.0 1.6 9.0 21.0 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Neur_chan_memb PF02932.16 CDJ69484.1 - 1.2 9.2 19.4 1.3 9.1 19.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_11 PF13086.6 CDJ69484.1 - 1.2 8.8 21.2 1.4 8.6 21.2 1.0 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 CDJ69484.1 - 1.5 7.0 20.1 1.7 6.8 20.1 1.0 1 0 0 1 1 1 0 CDC45-like protein RP-C_C PF11800.8 CDJ69484.1 - 1.6 8.8 20.7 1.9 8.5 20.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region PNISR PF15996.5 CDJ69484.1 - 1.6 8.9 26.9 2.1 8.6 26.9 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR TRAP_alpha PF03896.16 CDJ69484.1 - 1.7 7.8 10.3 2 7.5 10.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4569 PF15133.6 CDJ69484.1 - 1.9 8.1 23.7 2.4 7.8 23.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) CAC1F_C PF16885.5 CDJ69484.1 - 2 8.0 16.6 2.4 7.7 16.6 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Spem1 PF15670.5 CDJ69484.1 - 2.3 7.7 22.9 3 7.3 22.9 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Endostatin PF06482.11 CDJ69484.1 - 2.4 7.6 23.1 2.7 7.4 23.1 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Cellulose_synt PF03552.14 CDJ69484.1 - 2.5 6.5 8.8 2.7 6.4 8.8 1.0 1 0 0 1 1 1 0 Cellulose synthase LAP1C PF05609.12 CDJ69484.1 - 2.5 7.1 23.6 2.8 6.9 23.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop53 PF07767.11 CDJ69484.1 - 2.7 7.3 29.0 3.2 7.1 29.0 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) F-protein PF00469.20 CDJ69484.1 - 3.7 7.1 20.2 4.4 6.8 20.2 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Sin_N PF04801.13 CDJ69484.1 - 3.9 6.6 31.3 4.6 6.3 31.3 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region BORG_CEP PF14957.6 CDJ69484.1 - 4.1 8.6 15.7 5.3 8.2 15.7 1.2 1 0 0 1 1 1 0 Cdc42 effector Dynamin_N PF00350.23 CDJ69484.1 - 4.1 7.4 10.2 5.4 7.0 10.2 1.2 1 0 0 1 1 1 0 Dynamin family ALMT PF11744.8 CDJ69484.1 - 4.4 6.0 20.2 5.1 5.8 20.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CDK5_activator PF03261.15 CDJ69484.1 - 4.4 6.8 18.3 4.8 6.6 18.3 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Pal1 PF08316.11 CDJ69484.1 - 4.6 8.0 12.5 6.8 7.4 12.5 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein SAPS PF04499.15 CDJ69484.1 - 4.6 5.9 19.4 5.4 5.7 19.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GPCR_chapero_1 PF11904.8 CDJ69484.1 - 5.1 6.4 14.8 5.7 6.3 14.8 1.1 1 0 0 1 1 1 0 GPCR-chaperone Rrn6 PF10214.9 CDJ69484.1 - 5.3 5.4 29.7 5.6 5.3 29.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Macoilin PF09726.9 CDJ69484.1 - 5.4 5.5 19.2 6.4 5.2 19.2 1.0 1 0 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 CDJ69484.1 - 5.4 6.8 27.2 6.6 6.5 27.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ69484.1 - 5.6 5.8 16.3 6.4 5.7 16.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TYW3 PF02676.14 CDJ69484.1 - 6 6.2 12.6 6.9 6.0 12.6 1.1 1 0 0 1 1 1 0 Methyltransferase TYW3 DUF4228 PF14009.6 CDJ69484.1 - 6.1 7.2 13.1 8.1 6.8 13.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF4638 PF15472.6 CDJ69484.1 - 6.8 6.3 18.5 8.2 6.1 18.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Hid1 PF12722.7 CDJ69484.1 - 6.9 4.7 23.2 7.7 4.5 23.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Afi1 PF07792.12 CDJ69484.1 - 7.1 7.1 21.5 9.9 6.7 21.5 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking YABBY PF04690.13 CDJ69484.1 - 8.6 6.9 18.8 11 6.5 18.8 1.3 1 0 0 1 1 1 0 YABBY protein DUF2126 PF09899.9 CDJ69484.1 - 8.8 4.3 18.3 10 4.1 18.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CLN3 PF02487.17 CDJ69484.1 - 9.9 5.1 19.2 11 4.9 19.2 1.1 1 0 0 1 1 1 0 CLN3 protein DUF853 PF05872.12 CDJ69484.1 - 9.9 4.6 16.1 13 4.2 16.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF755 PF05501.11 CDJ69485.1 - 0.00067 19.9 4.7 0.00067 19.9 4.7 6.5 5 1 1 6 6 6 1 Domain of unknown function (DUF755) DUF2207 PF09972.9 CDJ69485.1 - 0.066 12.0 2.2 0.17 10.6 0.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RskA PF10099.9 CDJ69485.1 - 0.94 9.7 47.5 0.13 12.6 3.5 3.8 2 1 1 3 3 3 0 Anti-sigma-K factor rskA RAP1 PF07218.11 CDJ69485.1 - 3.9 5.6 6.4 5.5 5.2 6.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IMUP PF15761.5 CDJ69485.1 - 6 7.6 26.0 1 10.1 13.6 3.2 3 0 0 3 3 3 0 Immortalisation up-regulated protein Met_10 PF02475.16 CDJ69486.1 - 8e-11 42.1 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 CDJ69486.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF3523 PF12037.8 CDJ69487.1 - 4.2e-48 164.0 22.5 4.2e-48 164.0 22.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) SDH_beta PF03315.15 CDJ69487.1 - 0.032 14.6 1.7 0.058 13.8 0.3 2.1 1 1 1 2 2 2 0 Serine dehydratase beta chain ALMT PF11744.8 CDJ69487.1 - 4.8 5.9 10.6 7.4 5.3 10.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Macoilin PF09726.9 CDJ69487.1 - 5.7 5.4 25.3 8.5 4.8 25.3 1.2 1 0 0 1 1 1 0 Macoilin family DUF755 PF05501.11 CDJ69489.1 - 0.018 15.3 16.1 0.018 15.3 16.1 8.0 7 1 0 7 7 7 0 Domain of unknown function (DUF755) SUIM_assoc PF16619.5 CDJ69489.1 - 0.56 10.3 0.0 0.56 10.3 0.0 10.6 7 4 1 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 Coq4 PF05019.13 CDJ69490.1 - 6.1e-51 172.9 0.1 1.8e-48 164.8 0.0 2.2 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 TraV PF09676.10 CDJ69490.1 - 0.013 16.5 2.1 0.013 16.5 2.1 1.6 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) SUIM_assoc PF16619.5 CDJ69491.1 - 1.9 8.6 5.3 5.4 7.2 5.3 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RNA_pol_Rpb1_5 PF04998.17 CDJ69492.1 - 5e-27 95.0 0.1 1.7e-26 93.3 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 CDJ69492.1 - 3.5e-16 59.1 0.1 1.6e-15 57.0 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 PF04998.17 CDJ69493.1 - 2e-45 155.3 0.9 2.5e-43 148.5 0.9 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 DUF3446 PF11928.8 CDJ69493.1 - 0.57 10.5 24.5 3.4 8.0 4.2 4.0 3 0 0 3 3 3 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ69494.1 - 0.013 15.1 55.7 0.046 13.3 16.0 5.3 5 0 0 5 5 5 0 Nuclear RNA-splicing-associated protein DUF4667 PF15700.5 CDJ69494.1 - 0.74 9.9 41.8 2.5 8.1 0.2 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4667) EMP24_GP25L PF01105.24 CDJ69496.1 - 1.1e-28 100.5 0.0 1.7e-28 99.8 0.0 1.3 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD Guanylate_kin PF00625.21 CDJ69501.1 - 1.6e-49 168.0 0.0 1.9e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 CDJ69501.1 - 3.5e-05 24.3 0.1 6.2e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CDJ69501.1 - 0.00024 21.7 0.4 0.0018 18.8 0.5 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDJ69501.1 - 0.00082 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 CDJ69501.1 - 0.0032 17.6 0.9 0.053 13.7 0.9 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ69501.1 - 0.0071 16.6 0.0 0.048 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ69501.1 - 0.016 14.9 0.2 0.038 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CDJ69501.1 - 0.037 14.0 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 CDJ69501.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 CDJ69501.1 - 0.067 13.3 0.0 0.085 12.9 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CDJ69501.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NTPase RNase_H PF00075.24 CDJ69502.1 - 1.9e-29 102.7 0.0 1.6e-28 99.7 0.0 2.0 1 1 0 1 1 1 1 RNase H SpoIIE PF07228.12 CDJ69503.1 - 0.0094 15.9 0.0 0.042 13.8 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PBP PF01161.20 CDJ69504.1 - 4.7e-08 33.4 0.0 7.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_hydro_65m PF03632.15 CDJ69504.1 - 0.017 14.0 0.1 0.024 13.5 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain HEAT PF02985.22 CDJ69505.1 - 0.062 13.6 9.5 0.47 10.8 0.0 6.0 5 0 0 5 5 5 0 HEAT repeat SLATT_1 PF18181.1 CDJ69506.1 - 0.051 13.5 0.2 0.055 13.4 0.2 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Ecm29 PF13001.7 CDJ69506.1 - 0.073 11.7 0.2 0.094 11.4 0.2 1.1 1 0 0 1 1 1 0 Proteasome stabiliser DTW PF03942.15 CDJ69507.1 - 1.2e-13 51.2 0.0 3.8e-13 49.6 0.0 1.8 1 1 0 1 1 1 1 DTW domain Claudin_2 PF13903.6 CDJ69508.1 - 0.12 12.1 4.2 0.18 11.5 4.2 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TcpE PF12648.7 CDJ69508.1 - 0.19 12.3 0.6 0.34 11.5 0.6 1.4 1 0 0 1 1 1 0 TcpE family DUF5345 PF17280.2 CDJ69508.1 - 0.2 11.6 0.8 0.5 10.4 0.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Phage_holin_3_6 PF07332.11 CDJ69508.1 - 0.5 10.4 5.8 0.91 9.6 5.8 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TraL PF07178.11 CDJ69508.1 - 7.3 7.1 6.9 14 6.2 6.9 1.4 1 0 0 1 1 1 0 TraL protein Rpn3_C PF08375.11 CDJ69509.1 - 1.7e-21 76.4 3.3 4.3e-21 75.1 3.3 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CDJ69509.1 - 3.7e-21 75.6 1.2 1.3e-20 73.9 0.1 2.3 2 0 0 2 2 2 1 PCI domain CCDC32 PF14989.6 CDJ69509.1 - 0.027 14.4 2.9 1.2 9.1 0.1 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing 32 POR_N PF01855.19 CDJ69509.1 - 0.077 12.7 1.4 0.15 11.7 1.4 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Secretin_N_2 PF07655.13 CDJ69509.1 - 0.29 11.7 1.1 0.52 10.9 0.1 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain Macoilin PF09726.9 CDJ69511.1 - 2.1 6.8 11.3 2.5 6.5 11.3 1.2 1 0 0 1 1 1 0 Macoilin family Serendipity_A PF05482.12 CDJ69511.1 - 9.9 4.7 9.5 0.27 9.8 0.2 2.0 1 1 1 2 2 2 0 Serendipity locus alpha protein (SRY-A) PP2C_2 PF13672.6 CDJ69512.1 - 0.027 14.1 3.1 0.036 13.7 3.1 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C DUF1180 PF06679.12 CDJ69512.1 - 0.094 13.1 2.0 0.11 13.0 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF1631 PF07793.11 CDJ69512.1 - 0.33 9.3 4.2 0.37 9.2 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) YjbE PF11106.8 CDJ69512.1 - 1.7 8.9 14.7 4.5 7.6 14.7 1.7 1 1 0 1 1 1 0 Exopolysaccharide production protein YjbE Sox_N PF12444.8 CDJ69512.1 - 3.2 8.9 7.1 13 7.0 7.1 1.9 1 1 0 1 1 1 0 Sox developmental protein N terminal Mito_carr PF00153.27 CDJ69513.1 - 0.48 10.4 2.8 10 6.1 0.7 4.4 2 0 0 2 2 2 0 Mitochondrial carrier protein EMP70 PF02990.16 CDJ69514.1 - 8.4e-20 70.9 0.0 1.7e-13 50.1 0.0 3.3 2 1 1 3 3 3 3 Endomembrane protein 70 SR-25 PF10500.9 CDJ69514.1 - 5.3e-05 22.9 3.9 5.3e-05 22.9 3.9 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ69514.1 - 0.00047 20.5 5.0 0.00047 20.5 5.0 4.0 1 1 1 3 3 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ69514.1 - 0.0025 17.9 34.9 0.0036 17.4 34.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDK2AP PF09806.9 CDJ69514.1 - 0.014 15.4 7.0 0.014 15.4 7.0 3.9 5 0 0 5 5 4 0 Cyclin-dependent kinase 2-associated protein Hamartin PF04388.12 CDJ69514.1 - 0.023 13.4 9.3 0.032 12.9 9.3 1.2 1 0 0 1 1 1 0 Hamartin protein LptF_LptG PF03739.14 CDJ69514.1 - 0.027 13.3 0.0 0.087 11.7 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG OATP PF03137.20 CDJ69514.1 - 0.11 10.8 0.2 0.27 9.5 0.2 1.6 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family THOC2_N PF16134.5 CDJ69514.1 - 0.3 9.7 5.0 0.44 9.1 5.0 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus NnrU PF07298.11 CDJ69514.1 - 0.72 9.3 10.0 0.37 10.3 1.2 3.0 2 1 1 3 3 3 0 NnrU protein Renin_r PF07850.14 CDJ69514.1 - 2.1 9.0 4.2 10 6.8 1.5 2.8 2 0 0 2 2 2 0 Renin receptor-like protein EPL1 PF10513.9 CDJ69514.1 - 2.5 8.5 14.1 1.5 9.2 3.9 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like CNDH2_N PF06278.11 CDJ69514.1 - 3.5 7.9 10.5 0.2 11.8 3.8 2.1 1 1 1 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal SpoIIP PF07454.11 CDJ69514.1 - 3.8 6.9 8.5 0.35 10.3 2.2 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Ribosomal_L6e PF01159.19 CDJ69514.1 - 5.6 7.5 9.0 1.8 9.2 5.9 1.6 2 0 0 2 2 2 0 Ribosomal protein L6e DUF966 PF06136.13 CDJ69514.1 - 7.5 6.2 12.7 4.2 7.0 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) MRP-L47 PF06984.13 CDJ69515.1 - 5.8e-24 84.0 0.4 5.8e-24 84.0 0.4 2.0 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2175 PF09943.9 CDJ69515.1 - 0.32 11.3 3.4 0.4 11.0 1.8 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Noc2 PF03715.13 CDJ69517.1 - 1.4e-14 54.1 0.1 1.4e-14 54.1 0.1 2.2 3 0 0 3 3 3 1 Noc2p family SUIM_assoc PF16619.5 CDJ69517.1 - 0.00054 20.0 0.0 0.00054 20.0 0.0 8.3 6 3 0 6 6 6 2 Unstructured region C-term to UIM in Ataxin3 KH_1 PF00013.29 CDJ69518.1 - 1.1e-19 70.0 0.8 2.2e-08 33.8 0.0 3.2 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 CDJ69518.1 - 4.6e-05 23.2 0.2 0.024 14.5 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 CDJ69518.1 - 0.00073 19.6 0.8 1.8 8.7 0.0 2.8 3 0 0 3 3 3 2 NusA-like KH domain Voltage_CLC PF00654.20 CDJ69519.1 - 7.9e-67 226.0 36.1 1.4e-51 175.8 21.4 2.7 3 0 0 3 3 3 2 Voltage gated chloride channel Retrotrans_gag PF03732.17 CDJ69522.1 - 0.013 15.7 0.0 0.074 13.3 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein DNA_ligase_A_C PF04679.15 CDJ69523.1 - 0.023 15.3 0.0 0.023 15.3 0.0 1.0 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region SR-25 PF10500.9 CDJ69524.1 - 0.0015 18.2 14.7 0.0021 17.7 14.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein V_ATPase_I PF01496.19 CDJ69524.1 - 0.0067 14.4 1.0 0.0084 14.1 1.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Menin PF05053.13 CDJ69524.1 - 0.021 13.2 7.1 0.027 12.9 7.1 1.1 1 0 0 1 1 1 0 Menin RasGEF_N PF00618.20 CDJ69524.1 - 0.036 14.3 0.1 0.05 13.8 0.1 1.3 1 0 0 1 1 1 0 RasGEF N-terminal motif FAM104 PF15434.6 CDJ69524.1 - 0.04 14.5 8.4 0.062 13.9 8.4 1.3 1 0 0 1 1 1 0 Family 104 AATF-Che1 PF13339.6 CDJ69524.1 - 0.06 14.0 9.1 0.09 13.5 9.1 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF3446 PF11928.8 CDJ69524.1 - 0.064 13.6 18.9 0.28 11.5 14.1 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Uds1 PF15456.6 CDJ69524.1 - 0.082 13.1 10.8 0.14 12.3 10.8 1.3 1 0 0 1 1 1 0 Up-regulated During Septation MID_MedPIWI PF18296.1 CDJ69524.1 - 0.12 12.1 8.6 0.17 11.7 8.6 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Sulfotransfer_2 PF03567.14 CDJ69524.1 - 0.2 11.5 1.1 0.25 11.2 1.1 1.1 1 0 0 1 1 1 0 Sulfotransferase family TFIIA PF03153.13 CDJ69524.1 - 0.27 11.2 7.2 0.34 10.9 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ69524.1 - 0.27 10.7 10.7 0.37 10.3 10.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4570 PF15134.6 CDJ69524.1 - 0.29 11.1 6.0 0.53 10.3 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Vps39_1 PF10366.9 CDJ69524.1 - 0.3 11.4 3.2 0.68 10.2 3.2 1.6 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Smg8_Smg9 PF10220.9 CDJ69524.1 - 0.31 9.3 4.6 0.33 9.2 4.6 1.0 1 0 0 1 1 1 0 Smg8_Smg9 DUF4667 PF15700.5 CDJ69524.1 - 0.31 11.1 13.4 0.43 10.6 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Seryl_tRNA_N PF02403.22 CDJ69524.1 - 0.32 11.2 8.1 0.57 10.4 8.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Herpes_pp85 PF04637.12 CDJ69524.1 - 0.33 9.3 5.5 0.44 8.9 5.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Jnk-SapK_ap_N PF09744.9 CDJ69524.1 - 0.37 11.0 10.7 0.6 10.3 10.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Presenilin PF01080.17 CDJ69524.1 - 0.99 8.1 4.8 1.3 7.7 4.8 1.1 1 0 0 1 1 1 0 Presenilin AF-4 PF05110.13 CDJ69524.1 - 1.1 7.2 16.9 1.3 7.0 16.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FapA PF03961.13 CDJ69524.1 - 1.2 7.7 5.7 1.6 7.2 5.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 CDJ69524.1 - 1.6 7.9 5.5 2.2 7.4 5.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein CCDC84 PF14968.6 CDJ69524.1 - 3.3 7.2 11.0 6.6 6.3 6.9 2.0 2 0 0 2 2 2 0 Coiled coil protein 84 DUF1635 PF07795.11 CDJ69524.1 - 5.9 6.7 14.0 9.2 6.0 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Stevor PF17410.2 CDJ69524.1 - 6.2 6.3 8.1 0.17 11.4 2.1 1.5 2 0 0 2 2 1 0 Subtelomeric Variable Open Reading frame APG6_N PF17675.1 CDJ69524.1 - 7.4 7.1 18.1 14 6.2 6.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region RAP1 PF07218.11 CDJ69524.1 - 8.6 4.5 10.3 11 4.2 10.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BAF1_ABF1 PF04684.13 CDJ69525.1 - 2.7 6.9 13.7 3.5 6.6 13.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.9 CDJ69526.1 - 1e-05 25.3 23.7 0.00033 20.3 10.9 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Mito_carr PF00153.27 CDJ69526.1 - 0.0028 17.5 0.2 0.0028 17.5 0.2 4.5 2 2 2 4 4 4 1 Mitochondrial carrier protein DUF1635 PF07795.11 CDJ69526.1 - 0.83 9.5 7.0 1.2 8.9 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Pap_E4 PF02711.14 CDJ69526.1 - 0.97 10.4 4.6 5.9 7.9 1.1 2.3 2 0 0 2 2 2 0 E4 protein CCDC106 PF15794.5 CDJ69526.1 - 1.5 8.5 13.4 0.41 10.3 6.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 EBP50_C PF09007.11 CDJ69526.1 - 1.8 9.5 16.8 2.4 9.2 7.3 3.0 3 0 0 3 3 3 0 EBP50, C-terminal Secretin_N_2 PF07655.13 CDJ69526.1 - 4.2 8.0 20.2 3.4 8.3 10.3 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain TraG-D_C PF12696.7 CDJ69526.1 - 4.7 7.2 6.7 0.86 9.6 1.2 2.1 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG DUF755 PF05501.11 CDJ69526.1 - 7.4 6.9 38.1 1.3 9.3 9.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Pox_A12 PF04651.13 CDJ69526.1 - 9.4 6.2 14.9 5.6 7.0 5.5 2.4 2 0 0 2 2 2 0 Poxvirus A12 protein Lin-8 PF03353.15 CDJ69526.1 - 9.6 5.7 6.3 5.5 6.5 1.9 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist BUD22 PF09073.10 CDJ69527.1 - 5.1e-05 22.8 23.6 5.1e-05 22.8 23.6 1.5 2 0 0 2 2 2 1 BUD22 SOG2 PF10428.9 CDJ69527.1 - 1.7 7.7 32.9 2.2 7.4 32.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RskA PF10099.9 CDJ69527.1 - 2.6 8.3 41.1 0.58 10.4 14.1 3.0 2 1 0 2 2 2 0 Anti-sigma-K factor rskA GREB1 PF15782.5 CDJ69527.1 - 3 4.9 23.8 3.3 4.7 23.8 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CDJ69527.1 - 6.4 6.1 16.0 12 5.2 16.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TAF4 PF05236.14 CDJ69529.1 - 0.0042 16.9 15.0 0.0042 16.9 15.0 2.1 1 1 1 2 2 2 1 Transcription initiation factor TFIID component TAF4 family SR-25 PF10500.9 CDJ69529.1 - 0.0072 16.0 22.3 0.0072 16.0 22.3 2.3 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ69529.1 - 0.19 11.7 16.4 0.22 11.4 16.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 CDJ69529.1 - 6.8 6.8 21.0 11 6.2 21.0 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SR-25 PF10500.9 CDJ69530.1 - 0.00085 19.0 12.5 0.00085 19.0 12.5 26.3 23 4 2 25 25 25 6 Nuclear RNA-splicing-associated protein FAM104 PF15434.6 CDJ69530.1 - 2.8 8.5 0.0 2.8 8.5 0.0 20.5 18 3 3 22 22 22 0 Family 104 TruB_N PF01509.18 CDJ69532.1 - 8.4e-25 87.9 0.0 1.6e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TSA PF03249.13 CDJ69532.1 - 1.1 7.9 4.3 1.9 7.2 4.3 1.2 1 0 0 1 1 1 0 Type specific antigen EF-hand_7 PF13499.6 CDJ69533.1 - 4.7e-29 100.6 3.8 1.4e-08 35.1 0.2 4.9 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 CDJ69533.1 - 6.9e-16 56.5 13.8 0.00041 19.7 0.1 7.5 9 0 0 9 9 9 4 EF hand EF-hand_8 PF13833.6 CDJ69533.1 - 1.3e-14 53.7 9.5 3.7e-08 33.1 0.2 5.9 6 0 0 6 6 6 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ69533.1 - 1.7e-14 52.4 10.5 0.011 15.7 0.2 7.2 7 1 0 7 7 7 4 EF-hand domain Metallophos PF00149.28 CDJ69533.1 - 2e-05 25.2 0.0 5.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_5 PF13202.6 CDJ69533.1 - 0.00012 21.5 7.6 0.037 13.5 0.1 5.5 6 0 0 6 6 6 2 EF hand EF-hand_11 PF08976.11 CDJ69533.1 - 0.00034 21.4 0.1 0.07 14.0 0.0 4.1 3 1 1 4 4 4 1 EF-hand domain Apt1 PF10351.9 CDJ69533.1 - 9.1 5.0 14.8 17 4.1 14.8 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 CDJ69534.1 - 9.5e-05 21.8 6.4 9.5e-05 21.8 6.4 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter Apt1 PF10351.9 CDJ69534.1 - 0.00025 20.0 17.4 0.00025 20.0 17.4 1.8 2 1 0 2 2 2 1 Golgi-body localisation protein domain CLN3 PF02487.17 CDJ69534.1 - 0.00047 19.3 11.5 0.00047 19.3 11.5 1.8 2 0 0 2 2 2 1 CLN3 protein Velvet PF11754.8 CDJ69534.1 - 0.00085 19.3 13.0 0.00085 19.3 13.0 2.8 3 0 0 3 3 3 1 Velvet factor O-antigen_lig PF13425.6 CDJ69534.1 - 0.00086 18.2 1.3 0.0011 17.8 1.3 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Spore_coat_CotO PF14153.6 CDJ69534.1 - 0.00089 19.2 18.2 0.00089 19.2 18.2 2.1 2 0 0 2 2 2 1 Spore coat protein CotO SpoIIIAH PF12685.7 CDJ69534.1 - 0.0013 18.7 7.2 0.0013 18.7 7.2 3.1 3 0 0 3 3 3 1 SpoIIIAH-like protein V_ATPase_I PF01496.19 CDJ69534.1 - 0.0068 14.4 18.3 0.011 13.7 18.3 1.4 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HCO3_cotransp PF00955.21 CDJ69534.1 - 0.014 14.3 4.2 0.025 13.4 4.2 1.3 1 0 0 1 1 1 0 HCO3- transporter family Sec62 PF03839.16 CDJ69534.1 - 0.015 14.9 13.1 0.037 13.5 13.1 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3446 PF11928.8 CDJ69534.1 - 0.018 15.4 19.3 0.018 15.4 19.3 3.9 2 1 1 3 3 2 0 Early growth response N-terminal domain SID-1_RNA_chan PF13965.6 CDJ69534.1 - 0.025 13.0 7.6 0.014 13.9 3.7 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.10 CDJ69534.1 - 0.034 14.2 13.8 0.082 13.0 13.8 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF5523 PF17661.1 CDJ69534.1 - 0.06 13.0 16.4 0.13 12.0 16.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF2828 PF11443.8 CDJ69534.1 - 0.12 10.4 18.4 0.22 9.6 18.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) eIF-3_zeta PF05091.12 CDJ69534.1 - 0.22 10.5 23.8 0.34 9.8 23.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ69534.1 - 0.24 9.6 39.1 0.0062 14.9 32.6 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.16 CDJ69534.1 - 0.26 10.1 7.0 0.41 9.5 7.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Tim54 PF11711.8 CDJ69534.1 - 0.36 9.6 23.3 0.14 10.9 19.7 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 CDJ69534.1 - 0.63 9.4 19.0 1.7 8.0 19.0 1.7 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Dicty_REP PF05086.12 CDJ69534.1 - 0.92 7.4 11.1 1.3 6.9 11.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Otopetrin PF03189.13 CDJ69534.1 - 1.1 8.0 17.7 0.099 11.4 10.2 2.1 2 0 0 2 2 2 0 Otopetrin Membralin PF09746.9 CDJ69534.1 - 1.4 7.8 13.8 2.5 7.1 13.8 1.3 1 0 0 1 1 1 0 Tumour-associated protein SLC12 PF03522.15 CDJ69534.1 - 2.1 7.3 26.7 0.044 12.8 19.7 1.7 2 0 0 2 2 2 0 Solute carrier family 12 Nucleoside_tran PF01733.18 CDJ69534.1 - 2.7 7.3 4.6 4.8 6.5 4.6 1.3 1 0 0 1 1 1 0 Nucleoside transporter SelP_N PF04592.14 CDJ69534.1 - 2.8 7.3 36.6 5.5 6.3 36.6 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF572 PF04502.13 CDJ69534.1 - 3.1 7.3 23.8 0.059 13.0 10.7 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF572) XRN_M PF17846.1 CDJ69534.1 - 4.3 6.2 17.4 0.1 11.5 10.3 1.8 2 0 0 2 2 2 0 Xrn1 helical domain DUF2126 PF09899.9 CDJ69534.1 - 5.3 5.0 15.2 9.8 4.1 15.2 1.4 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DAG_kinase_N PF14513.6 CDJ69534.1 - 6.7 6.9 31.7 1.1 9.5 22.3 2.7 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus DUF4638 PF15472.6 CDJ69534.1 - 8.5 6.0 19.9 19 4.9 19.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF913 PF06025.12 CDJ69534.1 - 9.6 5.1 17.6 0.17 10.9 5.8 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) DUF4174 PF13778.6 CDJ69535.1 - 0.13 12.7 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) RIC3 PF15361.6 CDJ69537.1 - 0.01 16.3 21.0 0.014 15.8 21.0 1.2 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 7TM_GPCR_Srw PF10324.9 CDJ69537.1 - 0.15 11.3 7.3 0.2 10.9 7.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF2052 PF09747.9 CDJ69537.1 - 0.53 10.4 34.3 1.8 8.7 17.2 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF3402 PF11882.8 CDJ69537.1 - 0.59 9.2 35.4 0.7 8.9 35.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) FYDLN_acid PF09538.10 CDJ69537.1 - 1.1 10.0 22.4 2.9 8.6 10.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PRC2_HTH_1 PF18118.1 CDJ69537.1 - 1.3 9.8 32.4 3.8 8.4 8.6 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain CPSF100_C PF13299.6 CDJ69537.1 - 1.5 9.0 30.0 0.34 11.1 13.5 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal XRN_M PF17846.1 CDJ69537.1 - 2.9 6.7 23.7 4.1 6.2 23.7 1.2 1 0 0 1 1 1 0 Xrn1 helical domain FAM76 PF16046.5 CDJ69537.1 - 2.9 7.2 35.2 1.9 7.8 19.9 2.0 2 0 0 2 2 2 0 FAM76 protein Gti1_Pac2 PF09729.9 CDJ69537.1 - 3.2 7.8 32.3 0.38 10.8 16.3 2.0 2 0 0 2 2 2 0 Gti1/Pac2 family AUX_IAA PF02309.16 CDJ69537.1 - 3.3 7.5 20.8 4.6 7.0 20.8 1.2 1 0 0 1 1 1 0 AUX/IAA family SAGA-Tad1 PF12767.7 CDJ69537.1 - 3.3 7.4 28.8 3.8 7.2 28.8 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2828 PF11443.8 CDJ69537.1 - 4.3 5.3 33.3 2 6.4 20.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF3408 PF11888.8 CDJ69537.1 - 4.7 7.3 38.0 0.31 11.2 17.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) FAM176 PF14851.6 CDJ69537.1 - 9.2 5.9 26.6 3.5 7.3 4.9 2.1 2 0 0 2 2 2 0 FAM176 family Apt1 PF10351.9 CDJ69538.1 - 0.099 11.5 3.7 0.11 11.4 3.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1180 PF06679.12 CDJ69538.1 - 0.11 12.9 0.1 0.12 12.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SUIM_assoc PF16619.5 CDJ69539.1 - 0.0096 16.0 2.4 0.0096 16.0 2.4 10.7 10 1 1 11 11 11 6 Unstructured region C-term to UIM in Ataxin3 Phostensin_N PF13916.6 CDJ69539.1 - 0.018 15.3 2.1 0.018 15.3 2.1 9.1 8 1 1 9 9 9 0 PP1-regulatory protein, Phostensin N-terminal Proteasome PF00227.26 CDJ69540.1 - 1.2e-31 109.7 1.7 4.1e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit TraV PF09676.10 CDJ69540.1 - 0.31 12.0 2.5 0.53 11.3 2.5 1.4 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) FAM199X PF15814.5 CDJ69540.1 - 2.6 7.0 5.3 4.3 6.3 5.3 1.4 1 0 0 1 1 1 0 Protein family FAM199X SARG PF15385.6 CDJ69540.1 - 5.4 6.1 8.2 6.9 5.8 8.2 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Adeno_PV PF03910.13 CDJ69541.1 - 5 5.7 11.7 5.8 5.5 11.7 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV Utp14 PF04615.13 CDJ69542.1 - 0.21 10.1 15.9 0.26 9.8 15.9 1.1 1 0 0 1 1 1 0 Utp14 protein Mannosyl_trans2 PF04188.13 CDJ69542.1 - 0.3 10.4 0.6 0.4 9.9 0.6 1.1 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) FAM196 PF15265.6 CDJ69542.1 - 1.4 8.4 26.7 1.7 8.1 26.7 1.2 1 0 0 1 1 1 0 FAM196 family TFIIA PF03153.13 CDJ69542.1 - 3.5 7.5 17.7 4.4 7.2 17.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Radical_SAM PF04055.21 CDJ69543.1 - 1.6e-05 25.4 0.0 0.084 13.2 0.0 2.4 2 0 0 2 2 2 2 Radical SAM superfamily HemN_C PF06969.16 CDJ69543.1 - 0.0093 16.0 0.0 0.0093 16.0 0.0 2.9 2 1 0 2 2 2 1 HemN C-terminal domain CENP-O PF09496.10 CDJ69543.1 - 1.4 8.8 19.3 0.7 9.8 3.7 3.3 3 0 0 3 3 3 0 Cenp-O kinetochore centromere component DUF1645 PF07816.11 CDJ69543.1 - 4.7 7.7 63.7 0.44 11.1 5.6 6.2 6 0 0 6 6 6 0 Protein of unknown function (DUF1645) DUF456 PF04306.13 CDJ69546.1 - 0.021 15.1 4.9 0.04 14.2 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Romo1 PF10247.9 CDJ69546.1 - 0.21 12.0 4.1 0.73 10.3 4.1 2.0 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF1269 PF06897.12 CDJ69546.1 - 1.2 9.4 9.0 0.55 10.6 6.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Hep_59 PF07052.11 CDJ69547.1 - 8.7e-21 74.7 2.0 8.7e-21 74.7 2.0 2.0 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Aminotran_1_2 PF00155.21 CDJ69549.1 - 3.4e-39 135.1 0.0 1.4e-38 133.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II DAO PF01266.24 CDJ69550.1 - 5.8e-38 131.4 0.0 9.8e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CDJ69550.1 - 2.1e-29 102.0 0.0 4e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 CDJ69550.1 - 6.3e-05 22.5 0.8 0.01 15.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDJ69550.1 - 0.00047 19.5 0.1 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 CDJ69550.1 - 0.0013 17.9 1.9 0.045 12.8 0.4 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CDJ69550.1 - 0.042 13.1 0.1 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ABC_tran PF00005.27 CDJ69551.1 - 3.3e-19 69.8 0.3 2.1e-18 67.2 0.0 2.5 3 0 0 3 3 3 1 ABC transporter ABC_membrane PF00664.23 CDJ69551.1 - 1.3e-17 64.4 0.8 3.6e-16 59.6 0.8 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region SbcCD_C PF13558.6 CDJ69551.1 - 3.7e-05 23.9 0.0 0.00013 22.1 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 CDJ69551.1 - 0.00015 21.3 1.7 0.023 14.1 0.0 2.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ69551.1 - 0.00053 20.4 0.1 0.00053 20.4 0.1 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CDJ69551.1 - 0.0028 17.9 0.7 0.095 13.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ69551.1 - 0.025 14.3 0.1 0.061 13.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 CDJ69551.1 - 0.081 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDJ69551.1 - 0.13 11.9 0.3 0.3 10.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain FAM176 PF14851.6 CDJ69551.1 - 0.13 11.9 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 FAM176 family Patatin PF01734.22 CDJ69553.1 - 0.052 13.7 2.5 0.15 12.2 2.5 1.8 1 1 0 1 1 1 0 Patatin-like phospholipase Glutaredoxin PF00462.24 CDJ69555.1 - 9.2e-12 45.0 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin LRR_9 PF14580.6 CDJ69556.1 - 7.2e-09 35.4 0.1 1.7e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CDJ69556.1 - 0.056 13.9 3.5 7.5 7.1 2.1 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) GpcrRhopsn4 PF10192.9 CDJ69557.1 - 7.9e-09 35.3 0.4 7.9e-09 35.3 0.4 1.5 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Exo_endo_phos PF03372.23 CDJ69557.1 - 7.8e-07 28.8 0.0 7.8e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Flavodoxin_5 PF12724.7 CDJ69557.1 - 0.7 10.1 2.3 1.5 9.0 2.3 1.5 1 0 0 1 1 1 0 Flavodoxin domain SGS PF05002.15 CDJ69558.1 - 1.3e-29 102.1 0.6 3.3e-29 100.8 0.6 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.16 CDJ69558.1 - 1.4e-12 48.5 1.1 1.4e-12 48.5 1.1 1.8 2 0 0 2 2 2 1 CS domain Peptidase_M76 PF09768.9 CDJ69558.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 Peptidase M76 family AAA_assoc_C PF09821.9 CDJ69560.1 - 3.5 8.2 7.0 0.57 10.7 2.1 2.1 2 0 0 2 2 2 0 C-terminal AAA-associated domain DUF2722 PF10846.8 CDJ69561.1 - 2e-05 23.7 17.4 0.0053 15.8 10.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) M_domain PF12938.7 CDJ69561.1 - 0.011 15.6 3.4 0.011 15.6 3.4 3.8 2 1 0 3 3 1 0 M domain of GW182 OATP PF03137.20 CDJ69561.1 - 0.11 10.8 1.4 0.17 10.2 0.2 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4834 PF16118.5 CDJ69561.1 - 0.28 12.2 11.2 1.4 9.9 4.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Lin-8 PF03353.15 CDJ69561.1 - 0.71 9.4 14.7 1.6 8.3 6.7 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist RIC3 PF15361.6 CDJ69561.1 - 1.2 9.5 0.0 1.2 9.5 0.0 2.9 2 2 1 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 TMEM51 PF15345.6 CDJ69561.1 - 1.2 8.9 17.6 0.25 11.2 5.3 2.8 3 1 0 3 3 3 0 Transmembrane protein 51 Roughex PF06020.11 CDJ69561.1 - 2.8 7.0 16.8 0.27 10.3 5.2 2.4 2 0 0 2 2 2 0 Drosophila roughex protein POPLD PF08170.12 CDJ69561.1 - 3.5 8.0 7.6 2.3 8.6 2.2 2.4 2 0 0 2 2 2 0 POPLD (NUC188) domain FAM176 PF14851.6 CDJ69561.1 - 7.2 6.3 8.5 3.3 7.3 4.7 2.2 2 1 0 2 2 2 0 FAM176 family MG3 PF17791.1 CDJ69561.1 - 7.9 6.8 7.1 3.6 7.9 0.2 2.3 2 0 0 2 2 2 0 Macroglobulin domain MG3 MOLO1 PF17175.4 CDJ69562.1 - 4e-11 43.1 0.0 5.1e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 RskA PF10099.9 CDJ69563.1 - 0.00017 22.0 13.5 0.00017 22.0 13.5 2.7 2 1 1 3 3 3 1 Anti-sigma-K factor rskA Shadoo PF14999.6 CDJ69563.1 - 0.012 15.7 8.1 0.012 15.7 8.1 3.2 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective DUF3138 PF11336.8 CDJ69563.1 - 3.3 6.2 23.2 3.8 6.0 9.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Spt20 PF12090.8 CDJ69563.1 - 5.5 6.5 12.7 9.6 5.7 12.7 1.3 1 0 0 1 1 1 0 Spt20 family DUF4179 PF13786.6 CDJ69563.1 - 8.1 7.0 9.0 39 4.8 5.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) PseudoU_synth_2 PF00849.22 CDJ69564.1 - 4.8e-11 43.0 2.1 9.3e-11 42.1 0.1 2.2 1 1 1 2 2 2 1 RNA pseudouridylate synthase DUF2722 PF10846.8 CDJ69564.1 - 0.00035 19.7 15.8 0.083 11.8 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ69564.1 - 0.00054 19.6 24.5 0.011 15.3 1.2 2.1 2 0 0 2 2 2 2 Spt20 family TFIIA PF03153.13 CDJ69564.1 - 0.003 17.6 16.5 0.17 11.9 0.7 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ69564.1 - 0.0052 15.6 18.4 0.021 13.6 7.4 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4834 PF16118.5 CDJ69564.1 - 0.5 11.3 9.9 2 9.4 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RAB3GAP2_N PF14655.6 CDJ69564.1 - 1 8.5 8.0 7.4 5.7 3.4 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2681 PF10883.8 CDJ69564.1 - 1.6 9.2 20.3 2.3 8.7 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF3578 PF12102.8 CDJ69564.1 - 1.8 8.1 6.3 0.12 11.9 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3578) Dfp1_Him1_M PF08630.10 CDJ69564.1 - 1.9 8.7 5.6 9.8 6.4 0.3 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region UMP1 PF05348.11 CDJ69564.1 - 8.6 6.6 10.1 20 5.4 3.0 2.2 2 0 0 2 2 2 0 Proteasome maturation factor UMP1 Suf PF05843.14 CDJ69564.1 - 9.9 6.0 10.9 20 5.1 4.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Exonuc_VII_L PF02601.15 CDJ69565.1 - 0.0051 16.4 18.2 0.0074 15.9 18.2 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit SRP14 PF02290.15 CDJ69565.1 - 0.6 10.5 4.8 0.14 12.5 1.2 1.7 2 0 0 2 2 2 0 Signal recognition particle 14kD protein GET2 PF08690.10 CDJ69565.1 - 2.6 7.6 14.5 3.5 7.2 14.5 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Presenilin PF01080.17 CDJ69565.1 - 4.6 5.9 8.6 6.3 5.4 8.6 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ69565.1 - 7.4 4.7 25.3 8.9 4.4 25.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.13 CDJ69566.1 - 2e-05 24.4 8.9 2.9e-05 23.9 8.9 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) Caldesmon PF02029.15 CDJ69566.1 - 3.8e-05 22.7 7.6 4.7e-05 22.4 7.6 1.2 1 0 0 1 1 1 1 Caldesmon Presenilin PF01080.17 CDJ69566.1 - 0.0051 15.6 16.7 0.0051 15.6 16.7 1.4 2 0 0 2 2 2 1 Presenilin CDC45 PF02724.14 CDJ69566.1 - 0.0054 15.1 5.8 0.0065 14.8 5.8 1.2 1 0 0 1 1 1 1 CDC45-like protein FAM60A PF15396.6 CDJ69566.1 - 0.012 15.7 10.0 0.029 14.4 10.0 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Hamartin PF04388.12 CDJ69566.1 - 0.04 12.6 12.9 0.047 12.4 12.9 1.2 1 0 0 1 1 1 0 Hamartin protein PAT1 PF09770.9 CDJ69566.1 - 0.06 11.6 32.5 0.096 10.9 32.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Membralin PF09746.9 CDJ69566.1 - 0.07 12.2 7.8 0.1 11.6 7.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein GREB1 PF15782.5 CDJ69566.1 - 0.14 9.3 13.2 0.2 8.7 13.2 1.4 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer V_ATPase_I PF01496.19 CDJ69566.1 - 0.14 10.1 16.5 0.19 9.6 16.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 CDJ69566.1 - 0.41 9.2 10.7 0.56 8.8 10.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 CDJ69566.1 - 0.57 9.0 8.9 0.85 8.5 8.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Suf PF05843.14 CDJ69566.1 - 1.7 8.5 21.7 3.8 7.4 21.7 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Band_3_cyto PF07565.13 CDJ69566.1 - 1.8 8.3 14.8 3.3 7.5 14.8 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Allexi_40kDa PF05549.11 CDJ69566.1 - 3.3 7.1 10.6 5.1 6.5 10.6 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Serinc PF03348.15 CDJ69566.1 - 4.1 6.2 5.9 8 5.3 5.9 1.6 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2370 PF10176.9 CDJ69566.1 - 6.9 6.2 8.9 13 5.4 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4746 PF15928.5 CDJ69566.1 - 8.8 5.7 14.1 15 4.9 14.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CLP_protease PF00574.23 CDJ69567.1 - 1e-11 45.1 8.6 5.5e-09 36.2 1.1 4.1 3 1 0 3 3 3 2 Clp protease BLM10_mid PF16507.5 CDJ69568.1 - 8.3e-06 24.7 0.2 8.3e-06 24.7 0.2 2.3 3 0 0 3 3 3 1 Proteasome-substrate-size regulator, mid region SR-25 PF10500.9 CDJ69568.1 - 0.0017 18.0 2.6 0.0017 18.0 2.6 5.7 4 2 2 6 6 6 1 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ69568.1 - 0.074 13.6 0.3 0.074 13.6 0.3 5.4 4 2 1 5 5 5 0 TCP family transcription factor HCO3_cotransp PF00955.21 CDJ69568.1 - 0.48 9.2 4.0 0.9 8.3 4.0 1.4 1 0 0 1 1 1 0 HCO3- transporter family EPSP_synthase PF00275.20 CDJ69569.1 - 8.7e-25 87.3 11.5 7.4e-08 31.5 0.0 7.9 5 1 2 8 8 8 7 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CDJ69569.1 - 0.16 11.1 1.6 0.75 8.9 0.0 2.5 1 1 1 2 2 2 0 3-dehydroquinate synthase FapA PF03961.13 CDJ69569.1 - 9.6 4.7 6.7 33 2.9 6.7 1.8 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3446 PF11928.8 CDJ69570.1 - 0.0058 16.9 1.6 0.0058 16.9 1.6 4.6 3 1 0 3 3 3 1 Early growth response N-terminal domain IMUP PF15761.5 CDJ69570.1 - 0.022 15.5 8.5 0.022 15.5 8.5 5.0 3 1 1 4 4 4 0 Immortalisation up-regulated protein DUF4667 PF15700.5 CDJ69570.1 - 0.07 13.2 43.9 0.12 12.5 23.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ69570.1 - 3.1 7.6 44.3 1.1e+02 2.5 40.8 2.5 1 1 1 2 2 2 0 SPX domain PGK PF00162.19 CDJ69571.1 - 1.5e-99 333.5 5.5 2e-63 214.6 1.2 2.0 1 1 1 2 2 2 2 Phosphoglycerate kinase GramPos_pilinD1 PF16555.5 CDJ69571.1 - 0.011 15.9 0.3 0.018 15.2 0.3 1.4 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain RskA PF10099.9 CDJ69571.1 - 4.3 7.6 20.3 0.055 13.8 10.2 2.5 3 0 0 3 3 3 0 Anti-sigma-K factor rskA NAC PF01849.18 CDJ69572.1 - 4.6e-19 68.2 0.0 7.7e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 CDJ69572.1 - 0.0052 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain DUF2753 PF10952.8 CDJ69572.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) Pkinase PF00069.25 CDJ69573.1 - 6.8e-22 78.1 0.0 2.1e-11 43.7 0.3 2.9 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ69573.1 - 1.6e-08 34.1 0.0 0.00058 19.2 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ69573.1 - 0.00054 19.4 0.1 0.021 14.1 0.0 2.0 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 CDJ69573.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lon_C PF05362.13 CDJ69574.1 - 4.5e-35 121.1 0.6 1.1e-17 64.3 0.0 3.2 2 1 1 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CDJ69574.1 - 1e-17 64.8 0.0 4.2e-17 62.8 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 CDJ69574.1 - 3.6e-14 53.1 0.5 6.9e-13 49.0 0.0 2.7 2 1 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 CDJ69574.1 - 5.9e-07 29.6 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 CDJ69574.1 - 3.7e-06 26.1 0.0 6.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 CDJ69574.1 - 6.9e-05 23.3 0.0 6.9e-05 23.3 0.0 4.0 3 2 1 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 CDJ69574.1 - 0.00011 22.5 0.1 0.0019 18.5 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CDJ69574.1 - 0.00016 21.8 0.0 0.00016 21.8 0.0 3.3 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CDJ69574.1 - 0.00036 20.3 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein TFIIA PF03153.13 CDJ69574.1 - 0.00044 20.4 27.8 0.00044 20.4 27.8 3.2 2 1 0 2 2 1 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ69574.1 - 0.00055 18.6 22.0 0.00055 18.6 22.0 3.1 2 1 0 2 2 1 1 Macoilin family RuvB_N PF05496.12 CDJ69574.1 - 0.001 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDJ69574.1 - 0.011 15.9 0.0 0.011 15.9 0.0 3.0 3 0 0 3 3 1 0 AAA domain NACHT PF05729.12 CDJ69574.1 - 0.013 15.4 1.3 0.19 11.7 0.0 3.2 2 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 CDJ69574.1 - 0.034 14.5 0.0 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CNDH2_C PF16858.5 CDJ69574.1 - 0.041 13.8 17.6 0.024 14.5 7.3 2.5 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RsgA_GTPase PF03193.16 CDJ69574.1 - 0.049 13.5 0.0 0.049 13.5 0.0 2.3 2 0 0 2 2 1 0 RsgA GTPase TIP49 PF06068.13 CDJ69574.1 - 0.053 12.7 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 CDJ69574.1 - 0.063 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 CDJ69574.1 - 0.069 13.7 0.0 0.069 13.7 0.0 2.5 3 0 0 3 3 1 0 AAA domain NTPase_1 PF03266.15 CDJ69574.1 - 0.09 12.7 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 NTPase SpoIIP PF07454.11 CDJ69574.1 - 0.2 11.1 21.3 0.17 11.3 10.4 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) AAA_17 PF13207.6 CDJ69574.1 - 0.24 11.8 0.0 0.24 11.8 0.0 3.6 4 0 0 4 4 2 0 AAA domain AAA_23 PF13476.6 CDJ69574.1 - 4.7 7.6 0.0 3.2 8.2 1.1 4.4 4 1 0 4 4 2 0 AAA domain DUF5523 PF17661.1 CDJ69574.1 - 5 6.7 21.0 8.5 6.0 1.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DUF2722 PF10846.8 CDJ69576.1 - 0.00013 21.1 11.9 0.00013 21.1 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ69576.1 - 1.6 8.6 23.2 1.9 8.4 23.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ69576.1 - 2.1 7.0 5.0 2.3 6.9 5.0 1.0 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ69576.1 - 8 7.1 13.4 12 6.5 13.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 2OG-FeII_Oxy_3 PF13640.6 CDJ69577.1 - 4e-06 27.6 0.0 6.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF755 PF05501.11 CDJ69578.1 - 0.45 10.8 16.2 0.6 10.4 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MPM1 PF17234.2 CDJ69578.1 - 0.53 10.5 7.5 0.66 10.2 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 SR-25 PF10500.9 CDJ69578.1 - 1.1 8.9 16.1 0.45 10.1 13.9 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ69578.1 - 1.2 9.0 21.4 1.5 8.8 21.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Miga PF10265.9 CDJ69578.1 - 1.4 7.8 9.6 1.7 7.6 9.6 1.0 1 0 0 1 1 1 0 Mitoguardin Spt20 PF12090.8 CDJ69578.1 - 1.9 8.0 18.2 2.4 7.7 18.2 1.1 1 0 0 1 1 1 0 Spt20 family GREB1 PF15782.5 CDJ69578.1 - 4.2 4.4 10.3 4.4 4.3 10.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDJ69578.1 - 4.5 5.7 9.4 5.7 5.4 9.4 1.1 1 0 0 1 1 1 0 Macoilin family Plasmodium_Vir PF05795.11 CDJ69578.1 - 4.6 6.6 5.0 5 6.4 5.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TERB2 PF15101.6 CDJ69578.1 - 7.5 6.6 9.6 9.5 6.2 9.6 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Band_7 PF01145.25 CDJ69579.1 - 1.5e-29 103.3 0.0 2.7e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CDJ69579.1 - 3.6e-16 58.9 1.6 3.6e-16 58.9 1.6 2.0 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 CDJ69579.1 - 0.17 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Arf PF00025.21 CDJ69580.1 - 1.1e-20 73.8 0.0 9.8e-13 47.9 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family KOW PF00467.29 CDJ69581.1 - 0.00049 20.0 0.0 0.00065 19.6 0.0 1.2 1 0 0 1 1 1 1 KOW motif ER_lumen_recept PF00810.18 CDJ69582.1 - 1.3e-21 77.9 9.3 3.6e-21 76.5 9.3 1.7 1 1 0 1 1 1 1 ER lumen protein retaining receptor DUF3810 PF12725.7 CDJ69582.1 - 4.2 6.6 7.7 1.4 8.2 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3810) EMP70 PF02990.16 CDJ69583.1 - 3.3e-90 303.2 0.1 7e-90 302.1 0.1 1.4 1 1 0 1 1 1 1 Endomembrane protein 70 Pex14_N PF04695.13 CDJ69583.1 - 0.0011 19.6 1.5 0.0049 17.5 1.5 2.1 1 1 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.9 CDJ69583.1 - 0.0054 17.0 7.8 0.46 10.8 2.9 3.1 3 0 0 3 3 3 2 Anti-sigma-K factor rskA Pkinase_fungal PF17667.1 CDJ69583.1 - 0.034 12.9 0.4 0.063 12.0 0.4 1.4 1 1 0 1 1 1 0 Fungal protein kinase Jak1_Phl PF17887.1 CDJ69583.1 - 0.036 14.0 0.3 0.08 12.9 0.3 1.5 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain FTO_NTD PF12933.7 CDJ69583.1 - 0.057 12.6 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 FTO catalytic domain Spt20 PF12090.8 CDJ69583.1 - 0.093 12.3 10.2 0.17 11.5 10.2 1.4 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ69583.1 - 0.3 10.0 7.9 0.42 9.5 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Roughex PF06020.11 CDJ69583.1 - 2.3 7.2 5.3 3.3 6.7 5.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF4834 PF16118.5 CDJ69583.1 - 7.7 7.6 8.8 5.2 8.1 2.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Mnd1 PF03962.15 CDJ69584.1 - 0.054 13.8 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 Mnd1 HTH domain Methyltr_RsmB-F PF01189.17 CDJ69585.1 - 1.2e-31 110.0 0.0 7.8e-31 107.3 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 CDJ69585.1 - 3e-08 33.3 0.0 4.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CDJ69585.1 - 4.8e-07 29.7 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ69585.1 - 3.4e-05 24.5 0.0 7.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmF_N PF17125.5 CDJ69585.1 - 0.00051 20.5 0.0 0.47 11.0 0.0 2.5 1 1 1 2 2 2 2 N-terminal domain of 16S rRNA methyltransferase RsmF MTS PF05175.14 CDJ69585.1 - 0.00082 19.0 0.0 0.013 15.0 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase small domain GCD14 PF08704.10 CDJ69585.1 - 0.0022 17.7 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 CDJ69585.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 CDJ69585.1 - 0.019 14.6 0.0 0.056 13.1 0.0 1.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 FtsJ PF01728.19 CDJ69585.1 - 0.034 14.3 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 CDJ69585.1 - 0.08 13.7 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CDJ69585.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Skp1_POZ PF03931.15 CDJ69586.1 - 5.3e-10 39.3 0.0 1.7e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Herpes_pp85 PF04637.12 CDJ69586.1 - 0.98 7.8 2.5 1.4 7.3 2.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Patatin PF01734.22 CDJ69587.1 - 2.4e-29 103.0 1.3 2.4e-29 103.0 1.3 4.5 4 3 0 4 4 4 1 Patatin-like phospholipase HTH_AsnC-type PF13404.6 CDJ69587.1 - 1.9 8.3 4.9 9.7 6.1 4.9 2.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF4407 PF14362.6 CDJ69588.1 - 1.8 7.9 15.6 1.8 7.9 15.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Amino_oxidase PF01593.24 CDJ69589.1 - 1.1e-08 34.9 0.1 3.2e-08 33.3 0.1 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Myosin_head PF00063.21 CDJ69590.1 - 5.7e-174 580.0 0.0 6.6e-163 543.5 0.0 2.3 1 1 1 2 2 2 2 Myosin head (motor domain) MyTH4 PF00784.17 CDJ69590.1 - 3.2e-13 50.1 1.3 5.2e-12 46.2 0.0 3.6 3 1 1 4 4 4 1 MyTH4 domain IQ PF00612.27 CDJ69590.1 - 0.0011 18.6 0.4 0.0033 17.1 0.4 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_16 PF13191.6 CDJ69590.1 - 0.0092 16.4 1.2 0.12 12.7 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 CDJ69590.1 - 0.025 13.8 0.3 0.057 12.7 0.3 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 CDJ69590.1 - 0.051 13.8 2.7 0.28 11.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.7 CDJ69590.1 - 0.056 12.4 1.6 1.6 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Stk19 PF10494.9 CDJ69591.1 - 0.0027 17.4 0.2 0.0057 16.4 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Ribosomal_L1 PF00687.21 CDJ69592.1 - 1.1e-38 133.0 0.1 1.1e-38 133.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Acyl-CoA_dh_1 PF00441.24 CDJ69593.1 - 3.8e-25 88.9 4.8 5.5e-25 88.3 4.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDJ69593.1 - 4.7e-22 78.0 0.0 9.8e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Peptidase_C97 PF05903.14 CDJ69593.1 - 1.5e-18 67.1 0.0 2.3e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Acyl-CoA_dh_2 PF08028.11 CDJ69593.1 - 2e-05 24.8 2.0 3.1e-05 24.2 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LRAT PF04970.13 CDJ69593.1 - 0.027 14.8 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Rpr2 PF04032.16 CDJ69594.1 - 1.4e-05 25.3 0.0 1.4e-05 25.3 0.0 4.1 3 2 1 4 4 4 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain TPR_1 PF00515.28 CDJ69595.1 - 5.3e-05 22.9 3.5 0.034 14.0 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ69595.1 - 6e-05 22.9 4.9 0.065 13.4 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ69595.1 - 0.00028 21.3 1.2 0.0088 16.5 0.1 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ69595.1 - 0.034 14.8 0.2 0.034 14.8 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ69595.1 - 0.078 13.2 0.8 0.36 11.1 0.8 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CDJ69595.1 - 0.11 12.8 2.2 10 6.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ69595.1 - 0.11 12.5 1.9 0.47 10.6 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ69595.1 - 0.15 13.0 3.4 2.6 9.1 0.4 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ69595.1 - 0.23 11.8 9.6 0.39 11.0 0.6 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ69595.1 - 0.68 10.7 7.7 7.9 7.4 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CDJ69595.1 - 1.5 8.9 6.7 19 5.4 0.0 3.7 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 CDJ69595.1 - 1.8 8.3 4.3 69 3.2 0.1 3.7 4 0 0 4 4 4 0 TPR repeat Nucleoporin_N PF08801.11 CDJ69596.1 - 0.12 11.1 0.0 0.31 9.7 0.0 1.6 1 0 0 1 1 1 0 Nup133 N terminal like AAA PF00004.29 CDJ69597.1 - 5.7e-15 55.9 0.0 1.3e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CDJ69597.1 - 2.9e-14 53.1 0.0 5.3e-13 49.1 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 CDJ69597.1 - 6.5e-05 23.2 0.2 0.00024 21.4 0.1 2.0 2 0 0 2 2 2 1 AAA C-terminal domain AAA_22 PF13401.6 CDJ69597.1 - 0.0001 22.6 0.0 0.0015 18.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ69597.1 - 0.00017 21.4 0.1 0.00084 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CDJ69597.1 - 0.0003 20.6 0.0 0.00085 19.1 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CDJ69597.1 - 0.00033 20.1 0.0 0.0014 18.0 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CDJ69597.1 - 0.00043 20.6 0.2 0.028 14.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 CDJ69597.1 - 0.00058 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 CDJ69597.1 - 0.00075 20.1 0.0 0.0015 19.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 CDJ69597.1 - 0.0011 18.9 0.0 0.0054 16.7 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CDJ69597.1 - 0.0013 19.2 0.1 0.0086 16.5 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 CDJ69597.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CDJ69597.1 - 0.0016 17.5 0.2 0.25 10.3 0.0 2.6 2 1 1 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 CDJ69597.1 - 0.0016 18.4 0.1 0.0097 15.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 CDJ69597.1 - 0.0022 17.3 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 CDJ69597.1 - 0.0023 17.8 0.2 0.026 14.3 0.0 2.5 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 CDJ69597.1 - 0.0025 17.1 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain KTI12 PF08433.10 CDJ69597.1 - 0.0029 17.1 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CDJ69597.1 - 0.004 17.3 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CDJ69597.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 CDJ69597.1 - 0.02 15.0 0.0 0.05 13.7 0.0 1.6 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 CDJ69597.1 - 0.022 15.0 0.1 0.12 12.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 CDJ69597.1 - 0.039 13.7 0.0 12 5.6 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase Zot PF05707.12 CDJ69597.1 - 0.049 13.3 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_7 PF12775.7 CDJ69597.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 CDJ69597.1 - 0.09 12.8 0.0 0.24 11.4 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-AN1 PF01428.16 CDJ69598.1 - 9.6e-10 38.5 8.1 1.8e-09 37.6 8.1 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CDJ69598.1 - 0.013 15.9 5.0 0.024 15.0 5.0 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain IBR PF01485.21 CDJ69598.1 - 1 9.6 10.8 1.1 9.5 8.3 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain GTP_EFTU PF00009.27 CDJ69599.1 - 4.8e-66 222.0 0.2 7.3e-66 221.4 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CDJ69599.1 - 5.3e-31 106.9 0.0 4.8e-30 103.8 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CDJ69599.1 - 4.1e-19 68.4 0.0 8.9e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CDJ69599.1 - 9.3e-15 54.5 0.0 2.5e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CDJ69599.1 - 8.4e-12 45.3 0.1 2.2e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ69599.1 - 5.7e-05 23.2 0.1 0.00012 22.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 CDJ69599.1 - 0.023 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Shikimate_DH PF01488.20 CDJ69599.1 - 0.026 14.6 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SRPRB PF09439.10 CDJ69599.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Myosin_head PF00063.21 CDJ69600.1 - 1.3e-172 575.5 0.5 9.7e-137 457.0 0.2 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_16 PF13191.6 CDJ69600.1 - 0.011 16.1 0.0 0.034 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ69600.1 - 0.016 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 CDJ69600.1 - 0.027 14.1 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 CDJ69600.1 - 0.045 14.0 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CDJ69600.1 - 0.096 12.7 0.1 0.3 11.2 0.1 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 CDJ69600.1 - 0.11 12.8 0.1 0.49 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Ank_2 PF12796.7 CDJ69601.1 - 1.1e-26 93.3 0.0 6.7e-12 45.8 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ69601.1 - 3.2e-15 56.0 0.0 3.8e-05 23.9 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ69601.1 - 8.3e-15 55.0 0.2 1.2e-09 38.4 0.0 3.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ69601.1 - 4e-12 46.0 0.2 1.6e-05 25.1 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CDJ69601.1 - 7.7e-11 41.2 0.1 0.0033 17.8 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat CO_deh_flav_C PF03450.17 CDJ69604.1 - 0.08 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain Sigma70_r4_2 PF08281.12 CDJ69604.1 - 0.16 11.6 1.0 4.3 7.1 0.0 2.8 2 0 0 2 2 2 0 Sigma-70, region 4 RHD3 PF05879.12 CDJ69606.1 - 1.5e-108 364.0 0.0 1.9e-108 363.6 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 CDJ69606.1 - 0.0003 20.9 0.5 0.0013 18.8 0.3 2.2 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CDJ69606.1 - 0.00089 19.3 0.0 0.0025 17.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 CDJ69606.1 - 0.018 14.4 0.1 0.044 13.1 0.1 1.6 1 0 0 1 1 1 0 Septin GBP PF02263.19 CDJ69606.1 - 0.075 12.3 0.1 0.24 10.6 0.1 1.8 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Tctex-1 PF03645.13 CDJ69606.1 - 0.13 12.5 0.2 0.34 11.2 0.2 1.8 1 0 0 1 1 1 0 Tctex-1 family AAA_23 PF13476.6 CDJ69606.1 - 0.27 11.7 0.0 0.27 11.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDJ69606.1 - 0.69 10.1 4.9 0.58 10.4 0.1 3.2 3 1 0 3 3 3 0 AAA domain DUF445 PF04286.12 CDJ69606.1 - 0.83 9.4 5.5 7.8 6.2 5.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF445) RGS PF00615.19 CDJ69606.1 - 1.3 9.3 3.2 0.84 9.9 0.6 2.0 2 0 0 2 2 2 0 Regulator of G protein signaling domain RHH_5 PF07878.11 CDJ69607.1 - 0.045 13.6 1.1 0.17 11.8 0.1 2.5 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 tRNA-synt_1c PF00749.21 CDJ69608.1 - 1.1e-103 346.4 0.0 1.5e-103 346.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CDJ69608.1 - 8e-36 123.5 0.0 4.6e-35 121.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 CDJ69608.1 - 0.0063 16.5 0.1 0.016 15.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ69608.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GDA1_CD39 PF01150.17 CDJ69608.1 - 0.099 11.3 0.3 0.16 10.6 0.3 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family AlaDh_PNT_C PF01262.21 CDJ69609.1 - 0.044 13.1 0.2 0.071 12.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TF_Zn_Ribbon PF08271.12 CDJ69610.1 - 0.0041 16.6 0.4 0.0093 15.5 0.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Spore_III_AB PF09548.10 CDJ69610.1 - 0.018 15.2 1.1 0.033 14.3 0.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RPA_interact_C PF14768.6 CDJ69610.1 - 0.074 13.6 1.1 0.15 12.7 0.5 1.9 2 0 0 2 2 2 0 Replication protein A interacting C-terminal Rad50_zn_hook PF04423.14 CDJ69610.1 - 1.9 8.4 5.6 19 5.2 0.1 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif Roc PF08477.13 CDJ69611.1 - 1.1e-05 25.7 0.0 0.047 13.9 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CDJ69611.1 - 0.0013 19.1 1.4 0.0019 18.6 1.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 CDJ69611.1 - 0.01 15.4 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Ras family PduV-EutP PF10662.9 CDJ69611.1 - 0.2 11.4 0.0 0.8 9.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CpXC PF14353.6 CDJ69613.1 - 0.15 12.1 3.3 6.8 6.8 0.1 2.6 3 0 0 3 3 3 0 CpXC protein SPX PF03105.19 CDJ69613.1 - 0.64 9.9 4.4 0.78 9.6 4.4 1.0 1 0 0 1 1 1 0 SPX domain TFIIA PF03153.13 CDJ69613.1 - 1.2 9.1 15.1 1.4 8.9 15.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1180 PF06679.12 CDJ69613.1 - 4.3 7.7 15.5 3.9 7.9 13.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) MDFI PF15316.6 CDJ69614.1 - 2.7 8.1 10.1 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 MyoD family inhibitor DUF737 PF05300.11 CDJ69614.1 - 9.8 6.5 7.6 4.8 7.5 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Glyco_hydro_52 PF03512.13 CDJ69615.1 - 0.047 12.6 1.4 0.067 12.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 52 FERM_M PF00373.18 CDJ69615.1 - 0.14 12.6 4.6 0.87 10.0 3.0 2.5 1 1 1 2 2 2 0 FERM central domain RskA PF10099.9 CDJ69615.1 - 1.5 9.1 12.8 0.19 12.0 4.9 2.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ69615.1 - 2.7 7.6 24.7 0.21 11.2 18.8 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4692 PF15763.5 CDJ69615.1 - 6.6 7.2 8.9 18 5.8 8.9 1.7 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF3446 PF11928.8 CDJ69618.1 - 0.3 11.4 1.9 0.47 10.8 1.9 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain UMP1 PF05348.11 CDJ69619.1 - 0.18 12.0 5.7 0.43 10.8 5.7 1.6 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 Spt20 PF12090.8 CDJ69619.1 - 7.2 6.1 20.7 0.37 10.4 13.5 2.1 2 0 0 2 2 2 0 Spt20 family Spt20 PF12090.8 CDJ69620.1 - 0.043 13.4 13.7 0.066 12.8 13.7 1.3 1 0 0 1 1 1 0 Spt20 family DUF4446 PF14584.6 CDJ69620.1 - 0.11 12.4 0.4 0.11 12.4 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) RAP1 PF07218.11 CDJ69620.1 - 0.14 10.4 5.1 0.17 10.2 5.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Tmemb_cc2 PF10267.9 CDJ69620.1 - 0.18 10.9 16.4 0.2 10.8 15.2 1.7 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SPX PF03105.19 CDJ69620.1 - 0.28 11.1 15.2 0.36 10.7 15.2 1.1 1 0 0 1 1 1 0 SPX domain Spc24 PF08286.11 CDJ69620.1 - 3.4 8.0 18.2 3.3 8.0 0.3 3.3 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 IMP2_N PF18590.1 CDJ69621.1 - 7.5e-28 96.9 0.1 1.2e-27 96.3 0.1 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 CDJ69621.1 - 3.2e-26 91.0 1.1 7.5e-26 89.8 1.1 1.7 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain Dehydratase_MU PF02288.15 CDJ69621.1 - 0.0072 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Dehydratase medium subunit SR-25 PF10500.9 CDJ69622.1 - 0.048 13.3 8.0 0.057 13.0 8.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YscW PF09619.10 CDJ69622.1 - 0.19 12.1 0.0 0.28 11.6 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) DUF755 PF05501.11 CDJ69622.1 - 0.95 9.7 10.4 1.3 9.3 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) IMUP PF15761.5 CDJ69622.1 - 7.5 7.3 11.0 12 6.6 11.0 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein TFIIIC_delta PF12657.7 CDJ69623.1 - 0.8 9.6 12.4 2.8 7.8 12.4 1.8 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Presenilin PF01080.17 CDJ69623.1 - 4.8 5.8 20.9 5 5.8 20.9 1.0 1 0 0 1 1 1 0 Presenilin zf-C3HC4_3 PF13920.6 CDJ69624.1 - 2.9e-06 27.0 6.9 5.4e-06 26.2 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ69624.1 - 0.03 14.2 7.2 0.06 13.2 7.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TF_Zn_Ribbon PF08271.12 CDJ69626.1 - 1.7e-09 37.1 4.5 2.3e-09 36.6 4.5 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding DUF4503 PF14951.6 CDJ69626.1 - 0.024 13.1 1.0 0.03 12.8 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) A2L_zn_ribbon PF08792.10 CDJ69626.1 - 0.22 11.3 3.7 0.66 9.8 3.7 1.7 1 1 0 1 1 1 0 A2L zinc ribbon domain FA_desaturase PF00487.24 CDJ69626.1 - 0.74 9.6 5.1 0.9 9.3 5.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Glyco_trans_2_3 PF13632.6 CDJ69626.1 - 0.81 9.6 4.8 0.96 9.3 4.8 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 CobD_Cbib PF03186.13 CDJ69626.1 - 1.8 7.7 4.7 2 7.6 4.7 1.1 1 0 0 1 1 1 0 CobD/Cbib protein Phage_holin_3_6 PF07332.11 CDJ69626.1 - 2.4 8.2 20.6 4 7.5 20.6 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1676 PF07898.13 CDJ69626.1 - 4.6 7.2 8.0 5 7.1 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF2207 PF09972.9 CDJ69626.1 - 6.2 5.5 10.1 7.3 5.2 10.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PRA1 PF03208.19 CDJ69627.1 - 2.6e-20 72.5 1.0 3.5e-20 72.1 1.0 1.1 1 0 0 1 1 1 1 PRA1 family protein DctQ PF04290.12 CDJ69627.1 - 0.021 14.8 0.3 0.057 13.3 0.3 1.7 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component YwiC PF14256.6 CDJ69627.1 - 0.64 10.3 7.7 0.49 10.7 1.4 2.3 2 0 0 2 2 2 0 YwiC-like protein KH_1 PF00013.29 CDJ69628.1 - 1.6e-21 75.9 0.0 8.6e-08 31.9 0.0 6.2 6 0 0 6 6 6 4 KH domain KH_2 PF07650.17 CDJ69628.1 - 0.038 13.8 4.0 1.3 8.9 0.0 3.4 3 0 0 3 3 3 0 KH domain BMC PF00936.19 CDJ69628.1 - 0.71 9.9 0.0 0.71 9.9 0.0 4.1 6 0 0 6 6 6 0 BMC domain Prominin PF05478.11 CDJ69628.1 - 7 4.5 11.4 15 3.3 11.4 1.6 1 0 0 1 1 1 0 Prominin TolA_bind_tri PF16331.5 CDJ69629.1 - 0.00074 19.5 4.1 0.00074 19.5 4.1 4.6 5 1 1 6 6 6 3 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 CDJ69629.1 - 0.0075 16.3 6.6 0.0075 16.3 6.6 5.1 4 1 1 5 5 5 2 TPR/MLP1/MLP2-like protein Relaxase PF03432.14 CDJ69629.1 - 0.015 14.9 1.5 0.015 14.9 1.5 2.4 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain HALZ PF02183.18 CDJ69629.1 - 0.016 15.4 0.3 0.016 15.4 0.3 3.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper Mod_r PF07200.13 CDJ69629.1 - 1 9.5 28.8 0.72 9.9 5.5 4.4 4 0 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DUF948 PF06103.11 CDJ69629.1 - 1.4 9.2 10.4 4.9 7.5 0.2 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Latarcin PF10279.9 CDJ69629.1 - 2.3 8.7 7.0 19 5.7 1.4 2.8 2 0 0 2 2 2 0 Latarcin precursor RskA PF10099.9 CDJ69631.1 - 0.28 11.4 10.7 0.4 11.0 10.7 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA ANAPC_CDC26 PF10471.9 CDJ69631.1 - 1.6 9.6 26.2 0.7 10.8 13.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4407 PF14362.6 CDJ69631.1 - 1.7 7.9 8.9 2.2 7.5 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDJ69631.1 - 2.2 7.0 6.6 2.6 6.7 6.6 1.1 1 0 0 1 1 1 0 Presenilin Surface_antigen PF11054.8 CDJ69632.1 - 3.6e-25 89.0 4.3 5e-25 88.6 4.3 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ69633.1 - 1.1e-20 74.3 0.0 1.5e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Sec20 PF03908.13 CDJ69634.1 - 0.003 17.4 1.5 0.003 17.4 1.5 4.2 4 1 1 5 5 5 2 Sec20 HupE_UreJ_2 PF13795.6 CDJ69634.1 - 0.35 10.5 1.6 0.68 9.6 1.6 1.4 1 0 0 1 1 1 0 HupE / UreJ protein ARGLU PF15346.6 CDJ69634.1 - 2.8 7.8 10.1 0.37 10.7 0.3 2.5 3 0 0 3 3 3 0 Arginine and glutamate-rich 1 ANAPC4_WD40 PF12894.7 CDJ69636.1 - 8.3e-11 42.0 0.5 0.051 13.9 0.1 5.1 4 1 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ69636.1 - 1.4e-09 38.4 11.0 0.071 14.0 0.3 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Hira PF07569.11 CDJ69636.1 - 0.0017 18.1 0.1 2.1 8.0 0.0 3.1 3 0 0 3 3 3 2 TUP1-like enhancer of split SUIM_assoc PF16619.5 CDJ69636.1 - 0.0031 17.6 1.1 0.0031 17.6 1.1 3.1 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Ge1_WD40 PF16529.5 CDJ69636.1 - 0.0035 16.4 0.2 0.012 14.6 0.1 1.8 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_N PF14781.6 CDJ69636.1 - 0.0035 17.2 1.9 0.2 11.5 0.1 3.1 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal Nbas_N PF15492.6 CDJ69636.1 - 0.013 14.8 1.6 0.29 10.4 0.3 3.3 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal DUF4834 PF16118.5 CDJ69636.1 - 0.13 13.2 5.8 2.5 9.1 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ69636.1 - 0.33 10.5 30.6 0.16 11.6 9.1 2.3 2 0 0 2 2 2 0 Spt20 family Thg1C PF14413.6 CDJ69636.1 - 0.4 10.9 3.0 20 5.3 0.1 2.7 3 0 0 3 3 3 0 Thg1 C terminal domain Serpin PF00079.20 CDJ69637.1 - 2.2e-41 142.4 0.5 3.2e-23 82.7 0.6 2.3 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) SR-25 PF10500.9 CDJ69637.1 - 0.00022 20.9 4.7 0.00034 20.3 4.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ69637.1 - 0.19 11.7 16.6 0.014 15.4 10.8 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ69637.1 - 0.6 8.8 3.7 0.83 8.4 3.7 1.1 1 0 0 1 1 1 0 Presenilin DUF3446 PF11928.8 CDJ69637.1 - 1.5 9.2 10.6 0.73 10.2 6.8 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain Tim29 PF10171.9 CDJ69638.1 - 0.048 13.2 2.1 0.089 12.3 2.1 1.4 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 DUF3854 PF12965.7 CDJ69638.1 - 0.98 9.4 5.7 1.7 8.6 0.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3854) SR-25 PF10500.9 CDJ69639.1 - 0.00028 20.6 3.1 0.00031 20.4 3.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TssO PF17561.2 CDJ69639.1 - 0.01 16.0 4.1 0.011 15.8 4.1 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssO Spem1 PF15670.5 CDJ69639.1 - 0.11 12.1 12.9 0.13 11.8 12.9 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 TCL1_MTCP1 PF01840.17 CDJ69639.1 - 4.7 6.9 10.1 5.6 6.6 10.1 1.3 1 1 0 1 1 1 0 TCL1/MTCP1 family Spt20 PF12090.8 CDJ69639.1 - 7.4 6.1 25.7 10 5.7 25.7 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ69639.1 - 8.7 6.2 26.5 9.7 6.1 26.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Abhydrolase_3 PF07859.13 CDJ69640.1 - 0.0033 17.3 0.7 0.0033 17.3 0.7 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ribosomal_60s PF00428.19 CDJ69640.1 - 0.076 13.6 27.7 0.36 11.5 4.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ69640.1 - 1.1 9.5 21.8 1.5 9.1 8.5 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Kinesin PF00225.23 CDJ69643.1 - 5.7e-61 206.3 0.2 5.7e-61 206.3 0.2 2.9 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ69643.1 - 4e-11 43.1 1.1 4e-11 43.1 1.1 2.3 2 1 0 2 2 1 1 Microtubule binding DUF724 PF05266.14 CDJ69643.1 - 0.0031 17.4 9.7 0.0056 16.5 9.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF724) GAS PF13851.6 CDJ69643.1 - 0.011 15.1 19.8 0.011 15.1 19.8 2.0 3 0 0 3 3 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 CDJ69643.1 - 0.012 13.6 4.7 0.012 13.5 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 CDJ69643.1 - 0.018 15.1 15.8 0.037 14.0 15.8 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.13 CDJ69643.1 - 0.024 15.4 12.0 0.055 14.2 12.0 1.6 1 0 0 1 1 1 0 Occludin homology domain DUF4763 PF15960.5 CDJ69643.1 - 0.025 13.9 10.6 0.046 13.0 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Spc7 PF08317.11 CDJ69643.1 - 0.026 13.4 13.4 0.039 12.8 13.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein PCRF PF03462.18 CDJ69643.1 - 0.034 14.0 7.7 0.076 12.9 7.7 1.7 1 0 0 1 1 1 0 PCRF domain SHE3 PF17078.5 CDJ69643.1 - 0.037 13.7 10.1 0.062 13.0 10.1 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 FlaC_arch PF05377.11 CDJ69643.1 - 0.04 14.3 3.7 0.04 14.3 3.7 2.8 3 1 1 4 4 2 0 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.9 CDJ69643.1 - 0.04 13.4 12.7 0.063 12.7 12.7 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 FapA PF03961.13 CDJ69643.1 - 0.047 12.3 9.3 0.08 11.5 9.3 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A MIP-T3_C PF17749.1 CDJ69643.1 - 0.05 13.6 10.3 0.14 12.1 10.3 1.8 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Sec34 PF04136.15 CDJ69643.1 - 0.059 13.3 12.0 0.02 14.7 8.5 2.0 2 0 0 2 2 2 0 Sec34-like family TMF_TATA_bd PF12325.8 CDJ69643.1 - 0.059 13.6 16.0 0.13 12.5 16.0 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Med9 PF07544.13 CDJ69643.1 - 0.064 13.4 10.2 0.15 12.1 10.2 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Seryl_tRNA_N PF02403.22 CDJ69643.1 - 0.067 13.4 16.2 0.054 13.7 13.9 2.2 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DASH_Dam1 PF08653.10 CDJ69643.1 - 0.076 12.8 0.7 0.26 11.1 0.7 1.9 1 0 0 1 1 1 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 CDJ69643.1 - 0.085 13.3 5.2 0.31 11.5 4.3 2.4 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Med4 PF10018.9 CDJ69643.1 - 0.097 12.3 5.5 0.19 11.4 5.5 1.6 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 BRE1 PF08647.11 CDJ69643.1 - 0.1 12.7 18.3 0.1 12.7 16.5 2.0 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase SWI-SNF_Ssr4 PF08549.10 CDJ69643.1 - 0.11 11.2 13.9 0.0039 15.9 7.9 1.5 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) BLOC1_2 PF10046.9 CDJ69643.1 - 0.18 12.1 11.5 0.17 12.2 8.4 2.6 2 1 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 CDJ69643.1 - 0.19 11.7 11.9 0.072 13.1 8.2 2.3 2 0 0 2 2 1 0 Laminin Domain II COG2 PF06148.11 CDJ69643.1 - 0.21 11.7 6.4 0.79 9.8 6.4 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GP20 PF06810.11 CDJ69643.1 - 0.23 11.3 14.4 0.65 9.8 14.4 1.8 1 0 0 1 1 1 0 Phage minor structural protein GP20 CALCOCO1 PF07888.11 CDJ69643.1 - 0.25 10.2 13.8 0.34 9.7 13.8 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like MAD PF05557.13 CDJ69643.1 - 0.25 9.7 15.4 0.31 9.3 15.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Spectrin PF00435.21 CDJ69643.1 - 0.3 11.6 11.4 0.55 10.7 10.3 2.1 2 0 0 2 2 1 0 Spectrin repeat DUF3584 PF12128.8 CDJ69643.1 - 0.35 8.3 12.1 0.083 10.4 8.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fmp27_WPPW PF10359.9 CDJ69643.1 - 0.35 9.7 9.4 0.53 9.1 9.4 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF812 PF05667.11 CDJ69643.1 - 0.59 8.9 17.7 0.97 8.2 17.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fib_alpha PF08702.10 CDJ69643.1 - 0.66 10.2 10.7 4.1 7.6 8.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tup_N PF08581.10 CDJ69643.1 - 0.78 10.1 13.8 2.1 8.7 13.4 2.0 1 1 0 1 1 1 0 Tup N-terminal HAUS-augmin3 PF14932.6 CDJ69643.1 - 1.1 8.8 12.4 4.7 6.7 12.3 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 CDJ69643.1 - 1.1 9.3 8.2 5.5 7.0 7.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 CDJ69643.1 - 1.2 9.3 18.0 0.63 10.2 15.3 2.0 2 0 0 2 2 1 0 JNK_SAPK-associated protein-1 CENP-H PF05837.12 CDJ69643.1 - 1.3 9.5 14.7 5.2 7.5 14.7 2.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMPIT PF07851.13 CDJ69643.1 - 1.3 8.2 11.0 1.9 7.7 11.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein PRKG1_interact PF15898.5 CDJ69643.1 - 1.3 10.0 13.3 4.5 8.2 13.1 2.0 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain bZIP_1 PF00170.21 CDJ69643.1 - 1.4 9.1 11.1 0.13 12.3 5.0 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF2935 PF11155.8 CDJ69643.1 - 1.5 9.2 4.5 4.8 7.5 4.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) ESM4 PF15952.5 CDJ69643.1 - 1.5 9.2 9.6 2.6 8.4 9.6 1.4 1 0 0 1 1 1 0 Enhancer of split M4 family HAUS6_N PF14661.6 CDJ69643.1 - 1.5 8.3 8.2 3.1 7.3 8.2 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.15 CDJ69643.1 - 1.6 8.5 15.1 0.86 9.4 3.9 2.9 2 1 1 3 3 2 0 Septum formation initiator YabA PF06156.13 CDJ69643.1 - 2.1 9.0 10.6 8.3 7.1 10.0 2.4 2 1 0 2 2 1 0 Initiation control protein YabA Atg14 PF10186.9 CDJ69643.1 - 2.7 7.0 10.2 4.3 6.3 10.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Noelin-1 PF12308.8 CDJ69643.1 - 3.5 7.7 7.1 19 5.3 6.5 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein Nup54 PF13874.6 CDJ69643.1 - 4.5 7.4 11.5 10 6.2 11.5 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4298 PF14131.6 CDJ69643.1 - 5.2 7.1 9.9 40 4.3 9.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) End3 PF12761.7 CDJ69643.1 - 5.9 7.0 14.5 14 5.8 14.5 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 LMBR1 PF04791.16 CDJ69643.1 - 6.6 5.5 7.1 8.9 5.1 7.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 CDJ69643.1 - 7 7.2 20.1 30 5.1 20.4 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Spc24 PF08286.11 CDJ69643.1 - 8 6.8 15.0 4.3 7.6 5.9 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Filament PF00038.21 CDJ69643.1 - 9.9 5.6 21.0 1.5 8.3 16.0 2.1 2 1 1 3 3 2 0 Intermediate filament protein THOC7 PF05615.13 CDJ69645.1 - 0.00018 21.8 7.1 0.00018 21.8 7.1 2.4 2 0 0 2 2 2 1 Tho complex subunit 7 Sporozoite_P67 PF05642.11 CDJ69646.1 - 0.0012 17.0 0.9 0.0018 16.4 0.9 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Ion_trans PF00520.31 CDJ69647.1 - 2.3e-09 36.8 14.1 6.2e-05 22.4 7.4 2.1 1 1 1 2 2 2 2 Ion transport protein Tmemb_170 PF10190.9 CDJ69647.1 - 0.083 13.3 2.3 0.24 11.8 2.3 1.7 1 0 0 1 1 1 0 Putative transmembrane protein 170 FAM70 PF14967.6 CDJ69647.1 - 3.2 7.1 8.9 1.2 8.6 0.2 2.4 2 0 0 2 2 2 0 FAM70 protein UPF0176_N PF17773.1 CDJ69648.1 - 1.4e-20 73.5 0.0 3.4e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Methyltransf_3 PF01596.17 CDJ69648.1 - 1e-19 70.6 0.0 1.4e-10 40.8 0.0 2.5 2 1 0 2 2 2 2 O-methyltransferase Rhodanese_C PF12368.8 CDJ69648.1 - 2e-11 44.1 12.0 6.2e-11 42.5 12.0 1.9 1 0 0 1 1 1 1 Rhodanase C-terminal Methyltransf_24 PF13578.6 CDJ69648.1 - 1.9e-08 35.3 0.0 1.2e-07 32.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Rhodanese PF00581.20 CDJ69648.1 - 9.8e-08 32.5 0.0 2.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain tRNA_Me_trans PF03054.16 CDJ69649.1 - 8.3e-78 261.6 0.0 2.5e-70 237.1 0.0 2.5 2 1 0 2 2 2 2 tRNA methyl transferase SufE PF02657.15 CDJ69649.1 - 0.00095 19.0 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Fe-S metabolism associated domain ThiI PF02568.14 CDJ69649.1 - 0.072 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Rep_fac-A_3 PF08661.11 CDJ69650.1 - 1.1e-09 38.5 0.0 1.2e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 DUF150_C PF17384.2 CDJ69650.1 - 0.078 13.1 0.5 0.62 10.2 0.0 2.2 2 1 0 2 2 2 0 RimP C-terminal SH3 domain DUF1682 PF07946.14 CDJ69651.1 - 1.1 8.3 7.6 2.1 7.5 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TERB2 PF15101.6 CDJ69651.1 - 2 8.4 11.7 4.3 7.4 11.7 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RR_TM4-6 PF06459.12 CDJ69651.1 - 2.5 7.9 14.5 6.7 6.5 14.5 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PHD PF00628.29 CDJ69651.1 - 2.8 7.9 9.3 0.1 12.5 1.2 2.6 2 0 0 2 2 2 0 PHD-finger CDC45 PF02724.14 CDJ69651.1 - 4.8 5.3 12.8 8 4.6 12.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Carb_anhydrase PF00194.21 CDJ69652.1 - 1e-21 77.6 1.9 2.8e-13 50.0 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase SMC_ScpB PF04079.16 CDJ69652.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB MFS_1 PF07690.16 CDJ69653.1 - 4.2e-11 42.4 22.2 1.9e-08 33.6 23.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MAP17 PF15807.5 CDJ69653.1 - 0.059 13.6 0.7 0.059 13.6 0.7 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Stathmin PF00836.19 CDJ69653.1 - 0.42 10.6 12.5 0.97 9.4 12.5 1.5 1 0 0 1 1 1 0 Stathmin family TPR_1 PF00515.28 CDJ69655.1 - 4.6e-09 35.7 0.1 8e-07 28.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ69655.1 - 5.1e-07 29.3 0.0 0.0012 18.8 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat GFO_IDH_MocA PF01408.22 CDJ69655.1 - 6.3e-07 30.2 0.0 1.6e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TPR_8 PF13181.6 CDJ69655.1 - 1.3e-06 28.2 0.0 0.00031 20.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ69655.1 - 2e-05 24.8 0.4 0.09 13.1 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ69655.1 - 0.0021 18.7 0.1 9.8 7.3 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ69655.1 - 0.0039 17.1 0.0 0.83 9.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ69655.1 - 0.034 14.7 0.0 0.11 13.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ69655.1 - 0.073 12.8 0.0 2.1 8.1 0.1 2.6 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 CDJ69655.1 - 0.12 13.0 0.0 0.33 11.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat AIP3 PF03915.13 CDJ69658.1 - 0.085 11.9 3.9 0.12 11.4 3.9 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 AAA_11 PF13086.6 CDJ69659.1 - 1.3e-52 179.2 1.8 1.3e-52 179.2 1.8 6.0 6 2 0 6 6 6 1 AAA domain AAA_12 PF13087.6 CDJ69659.1 - 8.4e-33 113.7 0.0 2e-32 112.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CDJ69659.1 - 6.1e-31 107.6 3.5 2.2e-25 89.4 0.6 4.0 4 0 0 4 4 4 2 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CDJ69659.1 - 8.9e-13 48.8 5.1 8.9e-13 48.8 5.1 7.7 7 3 0 7 7 3 1 Signal recognition particle, alpha subunit, N-terminal R3H PF01424.22 CDJ69659.1 - 6.8e-09 35.6 0.0 2.7e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 R3H domain AAA_19 PF13245.6 CDJ69659.1 - 6e-07 29.9 0.0 0.00022 21.6 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CDJ69659.1 - 2e-06 27.7 0.1 2e-06 27.7 0.1 7.2 5 2 1 6 6 3 1 AAA domain zf-AN1 PF01428.16 CDJ69659.1 - 4.5e-06 26.7 8.8 7.9e-06 25.9 8.8 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger SPX PF03105.19 CDJ69659.1 - 1.1e-05 25.5 52.5 0.002 18.1 0.0 5.4 3 1 2 5 5 4 2 SPX domain AAA PF00004.29 CDJ69659.1 - 0.00033 21.1 0.8 0.097 13.1 0.0 4.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CDJ69659.1 - 0.0036 17.1 0.9 4.2 7.0 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CDJ69659.1 - 0.0046 17.2 13.9 0.035 14.4 0.0 6.2 5 2 1 6 6 5 1 AAA domain ResIII PF04851.15 CDJ69659.1 - 0.0096 15.9 0.0 0.29 11.1 0.0 3.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ69659.1 - 0.04 13.7 1.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 CDJ69659.1 - 0.046 13.3 10.1 0.05 13.2 0.1 3.2 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 CDJ69659.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) NTPase_1 PF03266.15 CDJ69659.1 - 0.18 11.7 0.6 1.1e+02 2.7 0.0 3.7 4 0 0 4 4 4 0 NTPase RNA_helicase PF00910.22 CDJ69659.1 - 0.18 12.2 0.3 11 6.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 CDJ69659.1 - 0.29 11.2 0.6 9.2 6.4 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase Spt20 PF12090.8 CDJ69659.1 - 0.96 9.0 96.2 1.3 8.6 18.3 5.5 5 0 0 5 5 5 0 Spt20 family Ssl1 PF04056.14 CDJ69660.1 - 7.7e-31 107.4 0.0 1.7e-30 106.3 0.0 1.5 1 0 0 1 1 1 1 Ssl1-like DUF2722 PF10846.8 CDJ69660.1 - 1.1e-06 27.8 12.6 2e-06 27.1 12.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ69660.1 - 0.00036 20.6 24.9 0.00036 20.6 24.9 1.8 2 0 0 2 2 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ69660.1 - 0.00042 20.5 0.4 0.00046 20.4 0.4 1.2 1 0 0 1 1 1 1 DDHD domain Presenilin PF01080.17 CDJ69660.1 - 0.001 17.9 3.3 0.001 17.9 3.3 1.5 2 0 0 2 2 1 1 Presenilin FAM91_C PF14648.6 CDJ69660.1 - 0.0016 17.3 1.4 0.0022 16.9 1.4 1.1 1 0 0 1 1 1 1 FAM91 C-terminus CPSF100_C PF13299.6 CDJ69660.1 - 0.0023 18.1 2.8 0.0049 17.1 2.8 1.5 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal CCDC53 PF10152.9 CDJ69660.1 - 0.0023 18.3 3.0 0.0023 18.3 3.0 2.1 3 0 0 3 3 1 1 Subunit CCDC53 of WASH complex MecA PF05389.12 CDJ69660.1 - 0.0029 17.3 1.6 0.0038 16.9 1.6 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) Med15 PF09606.10 CDJ69660.1 - 0.0037 16.0 24.5 0.0075 15.0 24.5 1.5 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal CIAPIN1 PF05093.13 CDJ69660.1 - 0.0042 17.6 4.6 0.011 16.2 4.6 1.7 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Connexin PF00029.19 CDJ69660.1 - 0.0056 16.5 2.8 0.008 16.0 2.8 1.2 1 0 0 1 1 1 1 Connexin SpoIIP PF07454.11 CDJ69660.1 - 0.0064 16.0 6.0 0.0092 15.5 6.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) PIEZO PF15917.5 CDJ69660.1 - 0.007 15.9 12.0 0.011 15.2 12.0 1.3 1 0 0 1 1 1 1 Piezo Gti1_Pac2 PF09729.9 CDJ69660.1 - 0.011 15.9 0.4 0.015 15.4 0.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Peroxin-13_N PF04088.13 CDJ69660.1 - 0.011 16.0 2.7 0.02 15.2 2.7 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4834 PF16118.5 CDJ69660.1 - 0.015 16.2 10.4 0.027 15.4 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ69660.1 - 0.015 15.3 10.8 0.02 14.9 10.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Baculo_PP31 PF05311.11 CDJ69660.1 - 0.02 14.4 5.5 0.03 13.8 5.5 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Band_3_cyto PF07565.13 CDJ69660.1 - 0.022 14.5 4.1 0.031 14.1 4.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain V_ATPase_I PF01496.19 CDJ69660.1 - 0.025 12.5 5.8 0.032 12.2 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 60KD_IMP PF02096.20 CDJ69660.1 - 0.026 14.4 4.8 0.041 13.8 4.8 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein Neur_chan_memb PF02932.16 CDJ69660.1 - 0.04 14.0 2.4 0.049 13.7 2.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2464 PF10240.9 CDJ69660.1 - 0.049 13.2 2.9 0.065 12.8 2.9 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 RR_TM4-6 PF06459.12 CDJ69660.1 - 0.051 13.4 5.9 0.07 12.9 5.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EOS1 PF12326.8 CDJ69660.1 - 0.052 13.5 0.5 0.076 12.9 0.5 1.3 1 0 0 1 1 1 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ69660.1 - 0.055 12.4 13.1 0.074 12.0 13.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MDM10 PF12519.8 CDJ69660.1 - 0.06 12.2 2.2 0.08 11.8 2.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 LMBR1 PF04791.16 CDJ69660.1 - 0.074 12.0 0.4 0.089 11.7 0.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein EPL1 PF10513.9 CDJ69660.1 - 0.078 13.4 7.6 0.13 12.7 7.6 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like AAA_23 PF13476.6 CDJ69660.1 - 0.087 13.3 11.0 0.12 12.9 11.0 1.2 1 0 0 1 1 1 0 AAA domain DUF4199 PF13858.6 CDJ69660.1 - 0.09 13.2 0.9 0.22 11.9 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) CLN3 PF02487.17 CDJ69660.1 - 0.17 10.9 3.9 0.28 10.2 3.9 1.3 1 0 0 1 1 1 0 CLN3 protein DUF2126 PF09899.9 CDJ69660.1 - 0.27 9.2 3.7 0.34 8.9 3.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PAT1 PF09770.9 CDJ69660.1 - 0.3 9.3 18.4 0.4 8.9 18.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CSG2 PF16965.5 CDJ69660.1 - 0.34 9.8 1.9 0.49 9.3 1.9 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator EIF4E-T PF10477.9 CDJ69660.1 - 0.35 9.7 15.6 0.44 9.3 15.6 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF3464 PF11947.8 CDJ69660.1 - 0.35 10.6 10.5 0.77 9.5 10.5 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 ALMT PF11744.8 CDJ69660.1 - 0.43 9.4 4.4 0.59 8.9 4.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1980 PF09323.10 CDJ69660.1 - 0.6 10.0 5.3 1 9.3 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Het-C PF07217.11 CDJ69660.1 - 0.62 8.5 4.6 0.81 8.2 4.6 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C TERB2 PF15101.6 CDJ69660.1 - 0.73 9.9 17.9 1.1 9.3 17.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EIIBC-GUT_N PF03612.14 CDJ69660.1 - 0.74 9.5 10.1 1.2 8.8 10.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Folliculin PF11704.8 CDJ69660.1 - 0.83 9.5 8.0 1.7 8.5 8.0 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Activator_LAG-3 PF11498.8 CDJ69660.1 - 1 8.2 44.9 1.5 7.7 44.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Tim54 PF11711.8 CDJ69660.1 - 1.1 8.0 8.4 1.6 7.5 8.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rbc25 PF08292.12 CDJ69660.1 - 1.1 9.5 10.1 1.9 8.7 10.1 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF4770 PF15994.5 CDJ69660.1 - 1.3 9.3 12.0 1.9 8.7 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) PIP5K PF01504.18 CDJ69660.1 - 1.4 8.1 8.2 1.9 7.6 8.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CTU2 PF10288.9 CDJ69660.1 - 1.5 9.1 15.8 0.022 15.0 8.2 1.9 2 0 0 2 2 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF2828 PF11443.8 CDJ69660.1 - 2 6.4 9.8 3 5.8 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF775 PF05603.12 CDJ69660.1 - 4.2 6.8 13.3 8.9 5.8 13.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Hid1 PF12722.7 CDJ69660.1 - 6 4.9 9.4 8.2 4.4 9.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MMR1 PF08505.10 CDJ69660.1 - 8.4 6.6 16.1 14 5.9 16.1 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Peptidase_S49_N PF08496.10 CDJ69660.1 - 8.9 6.4 12.4 19 5.3 12.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1635 PF07795.11 CDJ69661.1 - 3.7 7.4 10.2 5.6 6.8 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) SRP-alpha_N PF04086.13 CDJ69661.1 - 3.9 7.3 10.7 0.8 9.6 1.1 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Lin-8 PF03353.15 CDJ69661.1 - 7.6 6.0 6.5 12 5.4 6.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ69661.1 - 9.1 6.1 15.1 0.079 12.9 7.3 1.4 2 0 0 2 2 2 0 SPX domain MAT1 PF06391.13 CDJ69662.1 - 2.9 7.7 19.4 3.3 7.5 19.4 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 F-protein PF00469.20 CDJ69662.1 - 8.3 5.9 14.9 9.2 5.8 14.9 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Glycophorin_A PF01102.18 CDJ69663.1 - 3.8e-05 23.9 4.0 3.8e-05 23.9 4.0 2.4 1 1 2 3 3 3 1 Glycophorin A Macoilin PF09726.9 CDJ69663.1 - 0.15 10.6 40.5 0.17 10.4 40.5 1.0 1 0 0 1 1 1 0 Macoilin family SID-1_RNA_chan PF13965.6 CDJ69663.1 - 3 6.2 20.7 4.4 5.6 20.7 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Herpes_glycop PF01528.16 CDJ69663.1 - 4 6.2 5.4 4.9 5.9 5.4 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Helicase_C_2 PF13307.6 CDJ69664.1 - 4.2e-39 134.4 3.6 1.5e-38 132.6 0.1 3.1 2 1 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDJ69664.1 - 5.9e-30 104.2 0.0 5.9e-30 104.2 0.0 2.4 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 CDJ69664.1 - 0.00068 19.4 0.1 0.0057 16.4 0.1 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ69664.1 - 0.00074 19.6 2.3 0.33 10.9 0.1 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DUF2722 PF10846.8 CDJ69665.1 - 0.00076 18.5 2.4 0.00081 18.5 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) MFS_1 PF07690.16 CDJ69665.1 - 0.0045 16.0 5.1 0.0051 15.8 5.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily BRF1 PF07741.13 CDJ69665.1 - 0.027 14.8 0.1 0.036 14.4 0.1 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DHquinase_II PF01220.19 CDJ69665.1 - 0.043 13.5 0.1 0.071 12.8 0.1 1.3 1 0 0 1 1 1 0 Dehydroquinase class II Androgen_recep PF02166.16 CDJ69665.1 - 0.064 12.1 9.3 0.078 11.8 9.3 1.2 1 0 0 1 1 1 0 Androgen receptor DUF4834 PF16118.5 CDJ69665.1 - 0.064 14.2 1.6 0.088 13.8 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DivIC PF04977.15 CDJ69665.1 - 0.12 12.2 9.8 0.18 11.6 9.8 1.2 1 0 0 1 1 1 0 Septum formation initiator TFIIA PF03153.13 CDJ69665.1 - 0.17 11.8 9.2 0.18 11.8 9.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ69665.1 - 0.23 11.0 14.4 0.28 10.8 14.4 1.1 1 0 0 1 1 1 0 Spt20 family E_Pc_C PF06752.12 CDJ69665.1 - 1.3 9.1 11.3 1.6 8.8 11.3 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Roughex PF06020.11 CDJ69665.1 - 3.9 6.5 6.3 5.2 6.1 6.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein RNA_pol_Rbc25 PF08292.12 CDJ69666.1 - 3.5e-20 72.5 0.7 9.2e-09 35.6 0.4 2.8 2 1 0 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CDJ69666.1 - 4.1e-11 43.1 0.0 7.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CDJ69666.1 - 0.0056 17.0 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Ribosomal_60s PF00428.19 CDJ69666.1 - 0.024 15.2 11.5 0.045 14.3 11.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3108 PF11306.8 CDJ69666.1 - 0.43 10.5 1.8 0.59 10.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) SARAF PF06682.12 CDJ69667.1 - 1.3e-07 31.7 0.1 1.3e-07 31.7 0.1 4.2 3 1 0 4 4 4 2 SOCE-associated regulatory factor of calcium homoeostasis DUF755 PF05501.11 CDJ69667.1 - 0.002 18.4 31.0 0.002 18.4 31.0 5.8 5 1 1 6 6 6 1 Domain of unknown function (DUF755) Spt20 PF12090.8 CDJ69667.1 - 0.0039 16.8 1.4 0.0039 16.8 1.4 5.2 3 2 2 5 5 5 3 Spt20 family DUF2722 PF10846.8 CDJ69667.1 - 0.013 14.5 0.3 0.013 14.5 0.3 5.6 5 1 1 6 6 6 0 Protein of unknown function (DUF2722) Utp14 PF04615.13 CDJ69667.1 - 2.6 6.5 38.6 91 1.4 39.7 2.5 1 1 1 2 2 2 0 Utp14 protein GTP_EFTU PF00009.27 CDJ69668.1 - 8.2e-28 97.3 3.1 1.2e-25 90.2 0.0 4.0 3 1 0 3 3 2 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CDJ69668.1 - 3.6e-06 27.0 0.0 8.7e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II DUF4834 PF16118.5 CDJ69668.1 - 0.00024 22.0 5.4 0.00024 22.0 5.4 4.6 4 1 0 4 4 3 1 Domain of unknown function (DUF4834) DUF3446 PF11928.8 CDJ69668.1 - 0.00048 20.4 7.0 0.00048 20.4 7.0 8.5 5 3 3 9 9 5 1 Early growth response N-terminal domain EFG_C PF00679.24 CDJ69668.1 - 0.0037 17.3 0.0 0.024 14.6 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G C-terminus SR-25 PF10500.9 CDJ69668.1 - 0.0076 15.9 6.4 0.0076 15.9 6.4 6.5 7 0 0 7 7 5 1 Nuclear RNA-splicing-associated protein DUF1645 PF07816.11 CDJ69668.1 - 0.013 16.1 31.5 1.2 9.7 1.2 5.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1645) Neur_chan_memb PF02932.16 CDJ69668.1 - 0.031 14.3 11.9 0.43 10.6 0.2 3.4 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Tmemb_9 PF05434.11 CDJ69668.1 - 0.062 13.2 0.0 0.062 13.2 0.0 3.8 4 0 0 4 4 4 0 TMEM9 MecA PF05389.12 CDJ69668.1 - 0.42 10.2 4.9 0.6 9.7 0.4 3.1 4 0 0 4 4 4 0 Negative regulator of genetic competence (MecA) RNase_H2_suC PF08615.11 CDJ69668.1 - 0.58 10.3 5.7 8.4 6.6 0.1 3.4 4 0 0 4 4 4 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Cadherin_C_2 PF16492.5 CDJ69668.1 - 2.5 8.9 5.0 1.2 10.0 0.1 3.0 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal FAM60A PF15396.6 CDJ69668.1 - 4.6 7.2 11.1 5.2 7.0 0.1 3.9 4 0 0 4 4 4 0 Protein Family FAM60A Connexin PF00029.19 CDJ69668.1 - 4.8 6.9 10.4 0.097 12.4 0.3 2.7 3 0 0 3 3 3 0 Connexin CPSF100_C PF13299.6 CDJ69668.1 - 6.5 6.9 16.9 0.96 9.6 1.4 4.8 4 0 0 4 4 4 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CDJ69668.1 - 7 5.3 19.7 0.048 12.4 0.9 3.9 4 0 0 4 4 4 0 Presenilin Actin PF00022.19 CDJ69669.1 - 6.6e-21 74.4 0.0 6.6e-21 74.4 0.0 1.4 2 0 0 2 2 2 1 Actin DUF5308 PF17233.2 CDJ69669.1 - 0.00012 22.4 2.0 0.00012 22.4 2.0 2.8 2 1 0 2 2 1 1 Family of unknown function (DUF5308) TFIIA PF03153.13 CDJ69669.1 - 0.00089 19.4 48.2 0.075 13.0 20.3 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ69669.1 - 0.0014 19.3 3.3 0.0014 19.3 3.3 3.0 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 CDJ69669.1 - 0.0048 15.9 15.1 0.0048 15.9 15.1 3.1 2 1 1 3 3 1 1 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ69669.1 - 0.0097 16.3 3.4 0.0097 16.3 3.4 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like DUF572 PF04502.13 CDJ69669.1 - 0.011 15.4 17.9 0.11 12.1 4.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) HNOBA PF07701.14 CDJ69669.1 - 0.012 15.0 1.0 0.012 15.0 1.0 2.3 2 0 0 2 2 2 0 Heme NO binding associated DUF3391 PF11871.8 CDJ69669.1 - 0.023 15.3 5.1 0.023 15.3 5.1 2.9 2 1 0 2 2 1 0 Domain of unknown function (DUF3391) Presenilin PF01080.17 CDJ69669.1 - 0.035 12.9 24.8 0.049 12.4 6.7 2.1 2 0 0 2 2 2 0 Presenilin RNA_pol_Rpc4 PF05132.14 CDJ69669.1 - 0.079 13.4 17.1 1.1 9.6 7.1 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 MreB_Mbl PF06723.13 CDJ69669.1 - 0.091 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein CLN3 PF02487.17 CDJ69669.1 - 0.16 11.0 11.6 0.65 9.0 4.3 2.1 2 0 0 2 2 2 0 CLN3 protein Spore_coat_CotO PF14153.6 CDJ69669.1 - 0.24 11.3 28.6 1.4 8.8 7.0 2.2 2 0 0 2 2 2 0 Spore coat protein CotO eIF-3_zeta PF05091.12 CDJ69669.1 - 0.32 9.9 23.6 0.14 11.1 9.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1980 PF09323.10 CDJ69669.1 - 0.4 10.6 13.0 4.4 7.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF913 PF06025.12 CDJ69669.1 - 0.42 9.5 14.4 0.2 10.6 3.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) PA26 PF04636.13 CDJ69669.1 - 0.43 9.4 13.3 0.097 11.6 2.1 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) DUF4471 PF14740.6 CDJ69669.1 - 0.55 9.4 12.3 0.29 10.3 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Neur_chan_memb PF02932.16 CDJ69669.1 - 0.57 10.2 17.2 1.3 9.0 6.5 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 CDJ69669.1 - 0.6 9.1 21.7 0.067 12.2 6.3 2.1 2 0 0 2 2 2 0 Solute carrier family 12 DUF3807 PF12720.7 CDJ69669.1 - 0.61 10.3 29.4 0.29 11.4 11.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) MecA PF05389.12 CDJ69669.1 - 0.65 9.6 21.3 0.037 13.7 7.4 2.2 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) CPSF100_C PF13299.6 CDJ69669.1 - 0.73 10.0 23.0 0.56 10.4 9.7 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EOS1 PF12326.8 CDJ69669.1 - 0.74 9.7 14.6 0.9 9.4 4.2 2.3 2 0 0 2 2 2 0 N-glycosylation protein GAGA_bind PF06217.12 CDJ69669.1 - 0.77 10.0 14.8 1 9.6 5.6 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Golgin_A5 PF09787.9 CDJ69669.1 - 1 8.7 33.1 0.15 11.5 18.0 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 FAM60A PF15396.6 CDJ69669.1 - 1.5 8.8 22.4 2.2 8.2 6.2 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Connexin PF00029.19 CDJ69669.1 - 1.7 8.4 16.7 0.052 13.3 4.7 2.2 2 0 0 2 2 2 0 Connexin RR_TM4-6 PF06459.12 CDJ69669.1 - 1.7 8.4 27.0 0.23 11.3 10.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 CDJ69669.1 - 1.7 8.0 23.6 0.15 11.5 9.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Lin-8 PF03353.15 CDJ69669.1 - 2.1 7.8 32.3 0.8 9.2 8.9 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist FHIPEP PF00771.20 CDJ69669.1 - 2.3 6.6 11.2 0.069 11.6 3.1 2.0 2 0 0 2 2 2 0 FHIPEP family DUF2052 PF09747.9 CDJ69669.1 - 2.5 8.2 25.6 0.12 12.5 9.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Suf PF05843.14 CDJ69669.1 - 2.5 8.0 28.5 0.19 11.7 7.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) MDM10 PF12519.8 CDJ69669.1 - 2.8 6.7 18.8 2.6 6.8 6.6 2.2 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 PAP_RNA-bind PF04926.15 CDJ69669.1 - 2.9 7.5 17.6 6.2 6.4 9.9 2.2 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain GNAT_acetyltr_2 PF13718.6 CDJ69669.1 - 2.9 7.2 14.6 0.15 11.4 5.3 2.2 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Otopetrin PF03189.13 CDJ69669.1 - 3.1 6.5 5.9 0.92 8.3 0.3 2.1 2 0 0 2 2 2 0 Otopetrin CSG2 PF16965.5 CDJ69669.1 - 3.1 6.7 16.6 1.5 7.7 6.6 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator LTV PF04180.14 CDJ69669.1 - 3.1 7.4 27.0 3.1 7.4 10.1 2.1 2 0 0 2 2 2 0 Low temperature viability protein MMR1 PF08505.10 CDJ69669.1 - 3.9 7.7 34.3 0.11 12.8 9.3 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein PAT1 PF09770.9 CDJ69669.1 - 5.2 5.2 36.5 0.71 8.1 13.6 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Coilin_N PF15862.5 CDJ69669.1 - 5.2 6.9 31.8 5 6.9 7.0 2.4 2 0 0 2 2 2 0 Coilin N-terminus Endostatin PF06482.11 CDJ69669.1 - 5.3 6.4 22.5 2.6 7.4 6.7 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin XAP5 PF04921.14 CDJ69669.1 - 5.7 6.7 19.6 0.63 9.8 6.2 2.3 2 0 0 2 2 2 0 XAP5, circadian clock regulator CDC45 PF02724.14 CDJ69669.1 - 5.9 5.1 22.6 1.3 7.2 9.1 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF4638 PF15472.6 CDJ69669.1 - 6 6.5 15.0 0.48 10.1 5.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) Tim54 PF11711.8 CDJ69669.1 - 6.4 5.5 23.4 0.19 10.5 6.5 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.15 CDJ69669.1 - 7.8 5.2 16.6 3.8 6.2 6.6 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Zip PF02535.22 CDJ69669.1 - 9.1 5.4 10.5 0.83 8.8 0.2 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter zf-ANAPC11 PF12861.7 CDJ69671.1 - 3.2e-21 75.2 6.3 4.3e-21 74.8 6.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CDJ69671.1 - 4.5e-19 68.5 8.6 7.6e-19 67.8 8.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDJ69671.1 - 9.6e-08 32.2 7.9 7.1e-07 29.5 7.9 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CDJ69671.1 - 1.7e-05 24.7 7.9 3.2e-05 23.8 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ69671.1 - 6.3e-05 22.8 1.1 0.00014 21.7 1.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ69671.1 - 0.0022 18.0 7.2 0.007 16.4 5.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ69671.1 - 0.025 14.4 7.3 0.52 10.2 6.8 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ69671.1 - 0.033 14.1 5.8 0.15 12.0 5.7 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CDJ69671.1 - 0.68 9.6 10.4 2.9 7.6 10.4 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RanBP PF00641.18 CDJ69671.1 - 0.73 9.2 0.0 0.73 9.2 0.0 2.6 2 1 1 3 3 3 0 Zn-finger in Ran binding protein and others zf-RING_11 PF17123.5 CDJ69671.1 - 2.1 8.2 15.9 13 5.6 15.9 2.3 1 1 0 1 1 1 0 RING-like zinc finger Zip PF02535.22 CDJ69672.1 - 0.055 12.7 2.7 0.086 12.0 2.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 CDJ69672.1 - 0.71 8.6 24.2 1.4 7.7 24.2 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain SDA1 PF05285.12 CDJ69672.1 - 2.2 7.6 11.7 0.082 12.3 5.4 1.7 2 0 0 2 2 2 0 SDA1 SOBP PF15279.6 CDJ69672.1 - 2.6 8.6 24.9 1.2 9.7 18.8 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein PPP4R2 PF09184.11 CDJ69672.1 - 4.4 6.8 14.6 6.7 6.2 14.6 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 CDJ69672.1 - 6.9 4.7 8.1 11 4.1 8.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDJ69673.1 - 0.066 11.5 24.6 0.081 11.2 24.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SPX PF03105.19 CDJ69673.1 - 0.36 10.7 35.6 0.47 10.3 35.6 1.3 1 0 0 1 1 1 0 SPX domain GREB1 PF15782.5 CDJ69673.1 - 0.95 6.5 37.1 1.1 6.3 37.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ69673.1 - 8.5 4.5 54.7 9.7 4.3 54.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MAP65_ASE1 PF03999.12 CDJ69674.1 - 0.9 8.2 17.5 1 8.0 17.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) LCD1 PF09798.9 CDJ69674.1 - 2.4 6.6 6.5 2.7 6.4 6.5 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein MPM1 PF17234.2 CDJ69674.1 - 3.7 7.8 10.7 5.7 7.2 10.7 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Presenilin PF01080.17 CDJ69675.1 - 0.00016 20.6 4.7 0.00016 20.6 4.7 5.4 4 1 1 5 5 5 3 Presenilin RBFA PF02033.18 CDJ69679.1 - 2.1e-12 47.4 0.0 4.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Ribosome-binding factor A UDPGP PF01704.18 CDJ69681.1 - 5.5e-15 54.9 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase SUIM_assoc PF16619.5 CDJ69681.1 - 0.0017 18.3 0.4 0.0044 17.0 0.4 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ69681.1 - 5.1 6.6 15.2 0.7 9.5 11.2 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Med3 PF11593.8 CDJ69681.1 - 8.9 5.4 8.8 18 4.4 8.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CoA_binding PF02629.19 CDJ69683.1 - 8.5e-25 87.3 0.0 1.2e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain CoA_binding_2 PF13380.6 CDJ69683.1 - 0.00015 22.2 0.1 0.00023 21.6 0.1 1.3 1 0 0 1 1 1 1 CoA binding domain BAF1_ABF1 PF04684.13 CDJ69683.1 - 0.012 14.7 1.9 0.016 14.3 1.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GFO_IDH_MocA PF01408.22 CDJ69683.1 - 0.043 14.6 0.1 0.16 12.8 0.0 2.0 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Spt20 PF12090.8 CDJ69683.1 - 0.068 12.8 26.6 0.052 13.1 12.4 2.1 2 0 0 2 2 2 0 Spt20 family DUF1180 PF06679.12 CDJ69683.1 - 0.071 13.5 10.8 0.032 14.7 7.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SOG2 PF10428.9 CDJ69683.1 - 0.075 12.2 13.8 0.11 11.7 13.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Phostensin_N PF13916.6 CDJ69683.1 - 0.44 10.9 11.8 1.9 8.9 0.7 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Afi1 PF07792.12 CDJ69683.1 - 0.45 11.0 5.8 0.11 13.0 1.7 1.8 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4692 PF15763.5 CDJ69683.1 - 1.2 9.6 9.8 2.3 8.6 9.8 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF4551 PF15087.6 CDJ69683.1 - 1.3 7.7 16.4 0.08 11.8 11.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) GREB1 PF15782.5 CDJ69683.1 - 1.5 5.8 11.4 2.1 5.3 11.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 CDJ69683.1 - 1.6 6.8 8.1 2.3 6.2 8.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Miga PF10265.9 CDJ69683.1 - 1.9 7.3 9.0 2.7 6.8 9.0 1.2 1 0 0 1 1 1 0 Mitoguardin Presenilin PF01080.17 CDJ69683.1 - 2.3 6.9 9.7 0.82 8.4 6.8 1.6 2 0 0 2 2 2 0 Presenilin PEHE PF15275.6 CDJ69683.1 - 3.2 8.4 14.1 1.2 9.7 10.0 1.9 2 0 0 2 2 2 0 PEHE domain Ctr PF04145.15 CDJ69683.1 - 4.5 7.9 8.2 21 5.7 7.1 2.4 2 1 0 2 2 2 0 Ctr copper transporter family Plasmodium_Vir PF05795.11 CDJ69683.1 - 5.3 6.4 7.4 8 5.8 7.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SARAF PF06682.12 CDJ69683.1 - 5.5 6.5 14.8 1.9 8.1 11.3 1.8 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis PNISR PF15996.5 CDJ69683.1 - 7.9 6.7 11.7 4.1 7.6 7.1 2.0 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR EphA2_TM PF14575.6 CDJ69683.1 - 8.6 7.3 7.7 2.3e+02 2.8 0.0 3.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF5462 PF17547.2 CDJ69684.1 - 0.56 9.6 6.9 0.75 9.2 6.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5462) TFIIA PF03153.13 CDJ69684.1 - 7.6 6.4 8.8 9.3 6.1 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AIF-MLS PF14962.6 CDJ69684.1 - 8.5 6.3 27.8 11 6.0 27.8 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Med3 PF11593.8 CDJ69685.1 - 0.078 12.2 32.1 0.083 12.1 32.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2232 PF09991.9 CDJ69685.1 - 0.29 10.3 2.3 0.36 10.0 2.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) ThrE PF06738.12 CDJ69685.1 - 0.57 9.5 8.2 0.72 9.2 8.2 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter TrbI PF03743.14 CDJ69685.1 - 1.1 9.0 11.6 1.6 8.5 11.6 1.2 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein Dehydrin PF00257.19 CDJ69685.1 - 2.2 8.8 9.9 3 8.4 9.9 1.2 1 0 0 1 1 1 0 Dehydrin DUF2339 PF10101.9 CDJ69685.1 - 2.5 6.6 13.2 2.7 6.4 13.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) MDMPI_N PF11716.8 CDJ69685.1 - 3 8.5 23.9 3.3 8.4 23.9 1.0 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain R_equi_Vir PF05526.11 CDJ69685.1 - 4.9 7.0 11.4 5.7 6.8 11.4 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Senescence_reg PF04520.13 CDJ69686.1 - 0.013 16.4 5.9 0.015 16.1 5.9 1.1 1 0 0 1 1 1 0 Senescence regulator PA26 PF04636.13 CDJ69686.1 - 0.019 13.9 6.5 0.028 13.3 6.3 1.3 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) BBP1_N PF15271.6 CDJ69686.1 - 0.05 14.4 0.9 0.072 13.9 0.9 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein TFIIA PF03153.13 CDJ69686.1 - 0.12 12.4 22.5 0.16 12.0 22.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Yos1 PF08571.10 CDJ69686.1 - 1.4 9.2 3.1 2.1 8.6 0.7 2.0 1 1 1 2 2 2 0 Yos1-like IHABP4_N PF16174.5 CDJ69686.1 - 1.8 9.2 15.9 2.8 8.5 15.9 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal SUIM_assoc PF16619.5 CDJ69686.1 - 4.5 7.4 28.9 0.21 11.7 4.9 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TPX2 PF06886.11 CDJ69686.1 - 6.4 7.1 14.8 1.6 9.0 1.4 2.4 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Presenilin PF01080.17 CDJ69686.1 - 9.8 4.8 7.5 13 4.4 7.5 1.2 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 CDJ69687.1 - 0.78 8.8 22.2 1.1 8.3 22.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4407 PF14362.6 CDJ69687.1 - 4.9 6.4 35.8 6.7 6.0 35.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SARAF PF06682.12 CDJ69687.1 - 7.5 6.1 33.0 0.045 13.4 16.2 2.0 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis UPF0016 PF01169.19 CDJ69688.1 - 1e-10 41.7 11.2 1.9e-10 40.9 11.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 DUF1206 PF06724.11 CDJ69688.1 - 1.3 9.1 20.3 5.7 7.1 3.9 3.3 1 1 2 3 3 3 0 Domain of Unknown Function (DUF1206) DUF1645 PF07816.11 CDJ69691.1 - 0.025 15.1 0.2 0.025 15.1 0.2 10.6 5 3 3 9 9 9 0 Protein of unknown function (DUF1645) Comm PF15957.5 CDJ69691.1 - 0.28 11.5 0.0 0.28 11.5 0.0 3.5 4 0 0 4 4 4 0 Commissureless PAP2 PF01569.21 CDJ69691.1 - 0.46 10.3 4.8 1.9 8.3 0.0 3.8 3 0 0 3 3 3 0 PAP2 superfamily Stk19 PF10494.9 CDJ69692.1 - 1.1e-07 31.8 0.1 3e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 PNISR PF15996.5 CDJ69692.1 - 0.0022 18.3 8.7 0.0022 18.3 8.7 4.8 5 0 0 5 5 5 2 Arginine/serine-rich protein PNISR GRIP PF01465.20 CDJ69693.1 - 1.5e-14 53.6 1.2 8.3e-14 51.2 1.2 2.4 1 0 0 1 1 1 1 GRIP domain DUF572 PF04502.13 CDJ69694.1 - 0.12 12.0 12.9 0.059 13.0 6.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF913 PF06025.12 CDJ69694.1 - 0.35 9.8 5.7 0.83 8.6 2.6 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Herpes_pp85 PF04637.12 CDJ69694.1 - 1.6 7.1 4.6 2.2 6.6 1.3 2.2 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) GWT1 PF06423.12 CDJ69694.1 - 2.7 8.1 7.5 8 6.6 0.8 2.8 2 1 1 3 3 3 0 GWT1 Plant_zn_clust PF10533.9 CDJ69694.1 - 3.8 7.6 6.6 15 5.6 6.6 2.0 1 0 0 1 1 1 0 Plant zinc cluster domain SHE3 PF17078.5 CDJ69695.1 - 0.24 11.1 0.4 0.44 10.2 0.4 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 SID-1_RNA_chan PF13965.6 CDJ69696.1 - 0.14 10.6 4.0 0.24 9.8 4.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ69696.1 - 1.1 9.3 8.8 3 7.9 8.8 1.8 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 CDJ69696.1 - 1.7 8.4 8.2 3.5 7.3 6.3 2.0 2 0 0 2 2 2 0 Connexin Lin-8 PF03353.15 CDJ69696.1 - 3.8 7.0 24.8 0.71 9.4 8.4 3.1 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist Peptidase_S64 PF08192.11 CDJ69696.1 - 4.9 5.5 14.6 9.8 4.5 14.6 1.4 1 0 0 1 1 1 0 Peptidase family S64 EPL1 PF10513.9 CDJ69696.1 - 6.3 7.2 14.7 2.8 8.3 7.9 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like LCIB_C_CA PF18599.1 CDJ69696.1 - 7.4 5.8 8.8 43 3.3 8.8 2.3 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DEAD PF00270.29 CDJ69697.1 - 2.5e-35 121.8 3.5 8.4e-32 110.3 0.1 3.2 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ69697.1 - 2e-05 24.9 0.0 0.002 18.4 0.0 3.4 3 1 0 3 3 3 1 Helicase conserved C-terminal domain SUIM_assoc PF16619.5 CDJ69697.1 - 0.0076 16.3 5.9 0.0076 16.3 5.9 5.2 3 2 1 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 DUF4667 PF15700.5 CDJ69697.1 - 0.14 12.3 11.0 0.023 14.8 2.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) RskA PF10099.9 CDJ69697.1 - 7.7 6.8 69.0 0.1 12.9 20.5 4.6 4 0 0 4 4 4 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ69698.1 - 1.4e-05 24.8 18.4 1.4e-05 24.8 18.4 3.3 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ69698.1 - 0.0084 16.1 16.2 0.012 15.5 16.2 1.2 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 CDJ69698.1 - 0.35 9.7 18.3 0.45 9.3 18.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4776 PF16003.5 CDJ69698.1 - 0.43 9.5 6.7 0.58 9.1 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) CCDC106 PF15794.5 CDJ69698.1 - 1.3 8.7 28.0 0.13 11.9 9.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 SRP-alpha_N PF04086.13 CDJ69698.1 - 1.9 8.3 17.5 2.3 8.1 16.3 1.6 1 1 1 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Coilin_N PF15862.5 CDJ69698.1 - 4.6 7.0 10.4 1.2 8.9 3.5 2.2 2 0 0 2 2 2 0 Coilin N-terminus GREB1 PF15782.5 CDJ69698.1 - 8 3.4 21.5 9.9 3.1 21.5 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Secretin_N_2 PF07655.13 CDJ69698.1 - 9.5 6.8 36.3 3.4 8.3 11.9 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain zf-C2H2_2 PF12756.7 CDJ69699.1 - 0.042 14.2 0.1 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Hist_deacetyl PF00850.19 CDJ69700.1 - 5.3e-73 246.2 0.0 3.4e-56 191.0 0.0 2.5 2 1 0 2 2 2 2 Histone deacetylase domain SUIM_assoc PF16619.5 CDJ69701.1 - 0.0012 18.8 1.6 0.0026 17.8 1.6 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ69701.1 - 0.16 11.5 5.4 0.1 12.2 2.9 1.7 2 0 0 2 2 2 0 Spt20 family Med3 PF11593.8 CDJ69701.1 - 0.24 10.6 7.3 0.41 9.8 7.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DnaJ PF00226.31 CDJ69702.1 - 7.9e-25 86.8 0.2 1.5e-24 85.9 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Spt20 PF12090.8 CDJ69702.1 - 0.17 11.4 5.4 0.25 10.9 5.4 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ69703.1 - 0.0019 18.2 42.9 0.0024 18.0 42.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 CDJ69703.1 - 0.015 15.3 16.0 0.017 15.1 16.0 1.2 1 0 0 1 1 1 0 Velvet factor DUF5427 PF10310.9 CDJ69703.1 - 0.016 14.2 19.9 0.02 13.9 19.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CCSAP PF15748.5 CDJ69703.1 - 0.021 15.0 20.4 0.029 14.5 20.4 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated BAF1_ABF1 PF04684.13 CDJ69703.1 - 0.027 13.5 13.9 0.039 13.0 13.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Neur_chan_memb PF02932.16 CDJ69703.1 - 0.034 14.2 11.0 0.037 14.1 11.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SprA-related PF12118.8 CDJ69703.1 - 0.044 12.9 35.0 0.064 12.4 35.0 1.3 1 0 0 1 1 1 0 SprA-related family DUF572 PF04502.13 CDJ69703.1 - 0.046 13.3 15.4 0.051 13.2 15.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Endostatin PF06482.11 CDJ69703.1 - 0.046 13.2 13.8 0.053 13.0 13.8 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DDHD PF02862.17 CDJ69703.1 - 0.061 13.5 15.7 0.078 13.1 15.7 1.2 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ69703.1 - 0.07 12.1 24.8 0.08 11.9 24.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ69703.1 - 0.08 11.2 28.7 0.089 11.0 28.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ69703.1 - 0.11 11.2 25.0 0.13 11.0 25.0 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ69703.1 - 0.12 13.1 40.3 1.1 10.0 33.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region VIR_N PF15912.5 CDJ69703.1 - 0.12 11.9 5.6 0.14 11.8 5.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF1387 PF07139.11 CDJ69703.1 - 0.13 12.0 17.1 0.16 11.7 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Hamartin PF04388.12 CDJ69703.1 - 0.13 10.9 15.5 0.14 10.7 15.5 1.1 1 0 0 1 1 1 0 Hamartin protein MAJIN PF15077.6 CDJ69703.1 - 0.25 11.1 14.4 0.3 10.8 14.4 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein AF-4 PF05110.13 CDJ69703.1 - 0.25 9.4 23.6 0.27 9.3 23.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RR_TM4-6 PF06459.12 CDJ69703.1 - 0.52 10.1 21.8 0.66 9.8 21.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.15 CDJ69703.1 - 0.53 9.8 22.3 0.67 9.5 22.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist HemX PF04375.14 CDJ69703.1 - 0.59 9.4 35.9 0.73 9.1 35.9 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SID-1_RNA_chan PF13965.6 CDJ69703.1 - 0.62 8.4 6.7 0.81 8.0 6.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RskA PF10099.9 CDJ69703.1 - 0.62 10.3 39.7 6.1 7.1 39.7 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Tim54 PF11711.8 CDJ69703.1 - 0.65 8.7 16.0 0.86 8.3 16.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 CDJ69703.1 - 0.75 8.8 19.2 0.89 8.5 19.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Exonuc_VII_L PF02601.15 CDJ69703.1 - 0.77 9.3 17.6 1.1 8.7 17.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit YABBY PF04690.13 CDJ69703.1 - 1.4 9.4 12.2 2.1 8.9 12.2 1.4 1 0 0 1 1 1 0 YABBY protein SAPS PF04499.15 CDJ69703.1 - 1.5 7.5 14.5 1.7 7.4 14.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GREB1 PF15782.5 CDJ69703.1 - 1.5 5.8 22.0 1.7 5.7 22.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sec62 PF03839.16 CDJ69703.1 - 1.6 8.2 14.4 2 7.9 14.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 FAM60A PF15396.6 CDJ69703.1 - 1.7 8.6 18.1 2.4 8.1 18.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CobT PF06213.12 CDJ69703.1 - 1.8 7.9 31.9 2.6 7.4 31.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 CDJ69703.1 - 2 7.3 13.7 2.3 7.1 13.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PA26 PF04636.13 CDJ69703.1 - 3.4 6.5 15.3 4 6.3 15.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HAUS6_N PF14661.6 CDJ69703.1 - 4.3 6.9 19.3 5.3 6.6 19.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SpoIIP PF07454.11 CDJ69703.1 - 4.3 6.7 23.3 5.5 6.4 23.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Zip PF02535.22 CDJ69703.1 - 4.4 6.4 12.8 5.3 6.1 12.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Borrelia_P83 PF05262.11 CDJ69703.1 - 4.4 5.7 21.1 5.1 5.5 21.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase_fungal PF17667.1 CDJ69703.1 - 4.7 5.9 12.5 5.4 5.7 12.5 1.1 1 0 0 1 1 1 0 Fungal protein kinase LMBR1 PF04791.16 CDJ69703.1 - 4.7 6.0 9.6 5 5.9 9.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Serinc PF03348.15 CDJ69703.1 - 4.8 6.0 12.2 5.3 5.8 12.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CDC45 PF02724.14 CDJ69703.1 - 5.3 5.2 21.0 6.6 4.9 21.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Smg8_Smg9 PF10220.9 CDJ69703.1 - 6 5.0 21.1 7.4 4.7 21.1 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Connexin PF00029.19 CDJ69703.1 - 6.8 6.4 17.2 8.4 6.1 17.2 1.2 1 0 0 1 1 1 0 Connexin NPR3 PF03666.13 CDJ69703.1 - 6.8 5.4 24.4 8.8 5.0 24.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peroxin-3 PF04882.12 CDJ69703.1 - 7.1 5.5 21.5 8.1 5.3 21.5 1.1 1 0 0 1 1 1 0 Peroxin-3 DUF702 PF05142.12 CDJ69703.1 - 7.2 7.1 24.5 3.4 8.1 22.2 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF702) MDM10 PF12519.8 CDJ69703.1 - 7.5 5.3 18.8 9 5.0 18.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Hid1 PF12722.7 CDJ69703.1 - 9 4.3 24.9 11 3.9 24.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MMR1 PF08505.10 CDJ69703.1 - 9.1 6.5 29.2 12 6.0 29.2 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Raftlin PF15250.6 CDJ69703.1 - 9.6 4.8 22.5 12 4.5 22.5 1.0 1 0 0 1 1 1 0 Raftlin Thiolase_N PF00108.23 CDJ69704.1 - 4.6e-68 229.4 0.2 5.7e-68 229.1 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 CDJ69704.1 - 2.2e-05 24.2 0.7 5.2e-05 22.9 0.7 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Uteroglobin PF01099.17 CDJ69705.1 - 0.15 12.4 0.2 0.5 10.7 0.1 1.9 2 0 0 2 2 2 0 Uteroglobin family DUF2477 PF10631.9 CDJ69705.1 - 6.5 7.4 7.5 3.1 8.4 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) SUIM_assoc PF16619.5 CDJ69706.1 - 0.063 13.4 0.1 0.063 13.4 0.1 5.0 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 PFK PF00365.20 CDJ69707.1 - 1e-37 130.0 0.6 8.7e-35 120.4 0.0 3.8 3 1 0 3 3 3 3 Phosphofructokinase zf-CCCH PF00642.24 CDJ69708.1 - 1.4e-11 44.0 16.8 0.00081 19.2 0.5 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ69708.1 - 3.1e-08 33.2 11.9 1.3e-05 24.8 1.1 3.5 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDJ69708.1 - 4.7e-08 32.8 20.1 0.00081 19.4 2.3 3.5 3 0 0 3 3 3 3 Zinc finger domain CrtC PF07143.11 CDJ69708.1 - 0.11 13.2 14.9 0.056 14.1 1.3 2.9 2 0 0 2 2 2 0 CrtC N-terminal lipocalin domain zf-CCCH_3 PF15663.5 CDJ69708.1 - 0.14 12.4 8.4 0.09 13.0 2.9 3.0 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDJ69708.1 - 0.44 11.1 9.1 0.95 10.0 0.1 3.4 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Nmad2 PF18753.1 CDJ69708.1 - 2.9 7.3 5.6 8.4 5.8 5.6 1.7 1 0 0 1 1 1 0 Nucleotide modification associated domain 2 FeS_assembly_P PF01883.19 CDJ69709.1 - 0.00093 19.3 0.3 1.4 9.2 0.0 2.6 2 1 0 2 2 2 2 Iron-sulfur cluster assembly protein Glycophorin_A PF01102.18 CDJ69711.1 - 2.1 8.6 11.0 3.6 7.9 0.3 2.3 1 1 1 2 2 2 0 Glycophorin A FAM163 PF15069.6 CDJ69711.1 - 2.8 8.4 7.8 5 7.6 7.8 1.5 1 1 0 1 1 1 0 FAM163 family DUF966 PF06136.13 CDJ69711.1 - 5.3 6.7 13.4 6.9 6.3 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hamartin PF04388.12 CDJ69711.1 - 6.2 5.4 14.3 7.5 5.1 14.3 1.1 1 0 0 1 1 1 0 Hamartin protein SOG2 PF10428.9 CDJ69711.1 - 7 5.7 20.1 7.4 5.7 20.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Neur_chan_memb PF02932.16 CDJ69711.1 - 8.9 6.3 7.7 11 5.9 7.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CRM1_C PF08767.11 CDJ69712.1 - 4.1e-96 321.9 0.3 4.6e-96 321.8 0.3 1.0 1 0 0 1 1 1 1 CRM1 C terminal Ribosomal_60s PF00428.19 CDJ69712.1 - 0.062 13.9 2.6 0.14 12.8 2.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4834 PF16118.5 CDJ69713.1 - 0.085 13.8 6.1 0.14 13.1 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RED_N PF07808.13 CDJ69713.1 - 0.12 11.9 7.8 0.19 11.3 7.8 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region EPL1 PF10513.9 CDJ69713.1 - 0.26 11.6 5.4 0.42 11.0 5.4 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Spt20 PF12090.8 CDJ69713.1 - 0.28 10.8 26.1 0.43 10.2 26.1 1.2 1 0 0 1 1 1 0 Spt20 family DUF3506 PF12014.8 CDJ69713.1 - 0.35 10.9 2.8 0.53 10.3 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) EIF4E-T PF10477.9 CDJ69713.1 - 0.43 9.3 11.5 0.58 8.9 11.5 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RdRP_3 PF00998.23 CDJ69713.1 - 0.47 9.1 2.6 0.68 8.6 2.6 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase TERB2 PF15101.6 CDJ69713.1 - 1 9.4 9.3 1.6 8.7 9.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Med15 PF09606.10 CDJ69713.1 - 1.6 7.4 22.2 2.1 6.9 22.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ69713.1 - 2.8 7.8 23.8 3.9 7.4 23.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 CDJ69713.1 - 3.1 7.1 11.3 4.7 6.5 11.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT EIIBC-GUT_N PF03612.14 CDJ69713.1 - 3.9 7.2 5.8 6.1 6.5 5.8 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus UPF0560 PF10577.9 CDJ69713.1 - 6.3 5.2 12.8 8.2 4.8 12.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Presenilin PF01080.17 CDJ69713.1 - 7.1 5.3 7.3 9.7 4.8 7.3 1.1 1 0 0 1 1 1 0 Presenilin DEAD PF00270.29 CDJ69714.1 - 3.4e-36 124.6 10.3 3.4e-36 124.6 10.3 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ69714.1 - 5.5e-23 81.4 0.0 5.5e-23 81.4 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain GUCT PF08152.12 CDJ69714.1 - 1.9e-05 24.8 0.0 0.0054 17.0 0.0 3.2 2 0 0 2 2 2 1 GUCT (NUC152) domain Spt20 PF12090.8 CDJ69714.1 - 0.00079 19.1 30.3 0.00079 19.1 30.3 6.2 4 2 1 5 5 5 1 Spt20 family UTP25 PF06862.12 CDJ69714.1 - 0.13 11.0 0.0 0.13 11.0 0.0 3.3 4 0 0 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 CDJ69714.1 - 0.16 12.0 20.1 0.054 13.5 15.8 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 CDJ69714.1 - 0.36 10.1 0.0 0.36 10.1 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AP2 PF00847.20 CDJ69715.1 - 0.0018 18.5 0.4 0.0018 18.5 0.4 3.3 4 0 0 4 4 4 1 AP2 domain AAA_23 PF13476.6 CDJ69715.1 - 3.6 8.1 42.5 5.4 7.5 13.7 2.3 2 0 0 2 2 2 0 AAA domain Adenine_glyco PF03352.13 CDJ69715.1 - 5 6.9 9.5 0.58 9.9 1.3 2.6 2 0 0 2 2 2 0 Methyladenine glycosylase TFIIA PF03153.13 CDJ69716.1 - 0.25 11.3 26.8 0.31 11.0 26.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ69716.1 - 4.1 6.9 8.7 7 6.2 8.7 1.3 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ69717.1 - 7.9e-07 29.5 6.2 7.9e-07 29.5 6.2 3.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ69717.1 - 9.9e-05 22.1 7.1 9.9e-05 22.1 7.1 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ69717.1 - 0.00029 19.9 7.5 0.00029 19.9 7.5 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ69717.1 - 0.0011 19.7 8.7 0.0011 19.7 8.7 3.4 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region MID_MedPIWI PF18296.1 CDJ69717.1 - 0.0057 16.5 8.9 0.0057 16.5 8.9 2.3 2 0 0 2 2 2 1 MID domain of medPIWI Spt20 PF12090.8 CDJ69717.1 - 0.0083 15.8 12.6 0.0083 15.8 12.6 2.2 2 0 0 2 2 2 1 Spt20 family EPL1 PF10513.9 CDJ69717.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like CCSAP PF15748.5 CDJ69717.1 - 1.8 8.7 22.2 0.68 10.1 7.1 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated RIFIN PF02009.16 CDJ69717.1 - 1.8 8.4 16.3 0.11 12.3 6.8 2.1 2 0 0 2 2 2 0 Rifin Neur_chan_memb PF02932.16 CDJ69717.1 - 2.4 8.1 11.8 1.4 8.9 1.4 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Cation_ATPase PF13246.6 CDJ69718.1 - 3.4e-11 43.1 0.0 3.4e-11 43.1 0.0 3.1 4 0 0 4 4 4 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CDJ69718.1 - 2.5e-09 36.9 0.0 7.2e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ69718.1 - 1.7e-06 28.5 20.5 0.00027 21.3 20.5 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3318 PF11780.8 CDJ69718.1 - 0.011 15.7 3.5 0.011 15.7 3.5 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF3318) SpoIIP PF07454.11 CDJ69718.1 - 0.02 14.4 10.3 0.086 12.3 0.8 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 CDJ69718.1 - 0.025 13.4 5.6 0.58 8.9 1.4 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Spc24 PF08286.11 CDJ69718.1 - 0.057 13.7 10.3 5.4 7.3 0.2 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Presenilin PF01080.17 CDJ69718.1 - 0.14 10.9 7.0 1.2 7.8 0.5 2.3 2 0 0 2 2 2 0 Presenilin DUF2052 PF09747.9 CDJ69718.1 - 0.31 11.1 10.9 0.51 10.4 1.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Coilin_N PF15862.5 CDJ69718.1 - 0.33 10.8 14.9 0.2 11.4 0.5 2.5 2 0 0 2 2 2 0 Coilin N-terminus Connexin PF00029.19 CDJ69718.1 - 0.35 10.6 5.7 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Connexin Spt20 PF12090.8 CDJ69718.1 - 0.51 9.9 29.6 0.23 11.0 20.0 2.3 2 0 0 2 2 2 0 Spt20 family RR_TM4-6 PF06459.12 CDJ69718.1 - 0.66 9.8 11.7 2.2 8.1 3.8 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2722 PF10846.8 CDJ69718.1 - 0.94 8.3 21.7 1.1 8.2 15.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TRAP_alpha PF03896.16 CDJ69718.1 - 2.2 7.4 8.1 2.3 7.3 1.7 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Methyltransf_32 PF13679.6 CDJ69718.1 - 2.3 8.2 11.9 10 6.1 4.3 2.8 2 0 0 2 2 2 0 Methyltransferase domain Paf1 PF03985.13 CDJ69718.1 - 2.3 7.1 15.3 1.5 7.7 3.1 2.3 2 0 0 2 2 2 0 Paf1 RPN2_C PF18004.1 CDJ69718.1 - 2.4 8.0 16.6 7.4 6.5 8.2 2.5 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Rxt3 PF08642.10 CDJ69718.1 - 2.6 8.8 4.5 19 6.0 0.5 2.6 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Pinin_SDK_memA PF04696.13 CDJ69718.1 - 4.9 7.2 21.3 6.2 6.9 1.8 2.6 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF4820 PF16091.5 CDJ69718.1 - 5.4 6.3 12.5 2.9 7.2 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) CPSF100_C PF13299.6 CDJ69718.1 - 6.2 7.0 17.8 1.7 8.8 1.6 3.1 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal FAM176 PF14851.6 CDJ69718.1 - 8.2 6.1 9.4 13 5.4 2.3 2.4 2 0 0 2 2 2 0 FAM176 family FHIPEP PF00771.20 CDJ69718.1 - 8.7 4.7 8.5 1.2 7.6 0.5 2.1 2 0 0 2 2 2 0 FHIPEP family CD20 PF04103.15 CDJ69721.1 - 2.1 8.4 6.7 0.2 11.7 1.3 1.9 2 0 0 2 2 2 0 CD20-like family Glyco_transf_20 PF00982.21 CDJ69722.1 - 1.1e-56 192.5 1.8 1.4e-56 192.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CDJ69722.1 - 9e-35 119.9 0.0 1.4e-33 116.0 0.0 2.3 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 CDJ69722.1 - 9e-05 22.3 0.2 0.00072 19.4 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TFIIA PF03153.13 CDJ69722.1 - 0.046 13.7 19.3 0.065 13.2 19.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vac7 PF12751.7 CDJ69722.1 - 0.079 12.4 5.6 0.11 11.9 5.6 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 RR_TM4-6 PF06459.12 CDJ69722.1 - 0.086 12.7 11.1 0.14 11.9 11.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ69722.1 - 0.76 8.0 11.6 1.1 7.5 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 CDJ69722.1 - 4.6 7.2 5.6 7.1 6.6 5.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SUIM_assoc PF16619.5 CDJ69724.1 - 0.00052 20.0 0.5 0.0012 18.8 0.5 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Virul_fac_BrkB PF03631.15 CDJ69724.1 - 0.013 15.1 0.5 0.013 15.1 0.5 2.0 1 1 1 2 2 2 0 Virulence factor BrkB Spt20 PF12090.8 CDJ69724.1 - 0.15 11.7 2.8 0.2 11.2 2.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF4820 PF16091.5 CDJ69724.1 - 0.36 10.2 1.6 0.68 9.3 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Thymidylat_synt PF00303.19 CDJ69725.1 - 3.9e-31 108.2 0.0 6.2e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 CDJ69725.1 - 1e-27 96.8 0.2 2.1e-10 40.5 0.0 3.7 4 0 0 4 4 4 3 Dihydrofolate reductase FAM176 PF14851.6 CDJ69725.1 - 0.017 14.8 0.3 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 FAM176 family Presenilin PF01080.17 CDJ69725.1 - 0.31 9.8 5.1 0.57 8.9 5.1 1.3 1 0 0 1 1 1 0 Presenilin CNDH2_N PF06278.11 CDJ69725.1 - 0.64 10.3 5.6 13 6.0 0.1 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Neur_chan_memb PF02932.16 CDJ69725.1 - 0.85 9.6 2.0 1.5 8.8 2.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WASH-7_C PF14746.6 CDJ69725.1 - 1.1 8.9 7.0 29 4.3 0.4 3.1 3 0 0 3 3 3 0 WASH complex subunit 7, C-terminal ANAPC_CDC26 PF10471.9 CDJ69725.1 - 5.1 8.0 31.0 2.5 9.0 6.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 DNA_pol3_a_NII PF11490.8 CDJ69725.1 - 9.8 6.1 20.1 0.9 9.4 7.0 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II RRM_1 PF00076.22 CDJ69726.1 - 5.9e-08 32.4 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.19 CDJ69726.1 - 0.35 11.5 14.2 2.2 8.9 8.1 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein EXOSC1 PF10447.9 CDJ69727.1 - 7.5e-09 36.2 0.2 5.3e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 CDJ69727.1 - 1.3e-07 31.3 0.2 3.1e-07 30.1 0.2 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region RAP PF08373.10 CDJ69728.1 - 3.5e-10 39.8 0.0 6.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 RAP domain Neur_chan_memb PF02932.16 CDJ69728.1 - 0.029 14.4 12.0 0.26 11.3 6.5 2.7 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ69728.1 - 0.33 9.7 18.6 0.039 12.7 7.0 2.3 2 0 0 2 2 2 0 Presenilin P5-ATPase PF12409.8 CDJ69728.1 - 3.5 7.8 7.9 0.75 9.9 0.2 2.8 3 0 0 3 3 3 0 P5-type ATPase cation transporter Connexin PF00029.19 CDJ69728.1 - 5.2 6.8 12.7 1.2 8.9 2.3 2.7 3 0 0 3 3 3 0 Connexin DUF2464 PF10240.9 CDJ69728.1 - 9.8 5.7 9.0 2.6 7.6 3.5 2.1 2 0 0 2 2 2 0 Multivesicular body subunit 12 Pkinase_Tyr PF07714.17 CDJ69729.1 - 1.2e-35 123.1 0.0 1.9e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ69729.1 - 1e-33 116.8 0.0 2.8e-30 105.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain SAM_2 PF07647.17 CDJ69729.1 - 1.6e-05 24.9 0.0 2.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDJ69729.1 - 0.00013 22.3 0.0 0.00022 21.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 CDJ69729.1 - 0.0053 15.6 0.2 0.0096 14.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Spt20 PF12090.8 CDJ69729.1 - 0.41 10.2 15.1 0.67 9.5 15.1 1.3 1 0 0 1 1 1 0 Spt20 family APH PF01636.23 CDJ69729.1 - 1.7 8.5 0.0 1.7 8.5 0.0 3.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF2722 PF10846.8 CDJ69729.1 - 1.8 7.4 13.2 3 6.7 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Bacteriocin_IIc PF10439.9 CDJ69730.1 - 1.3 9.2 12.7 1.8 8.8 5.4 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Otopetrin PF03189.13 CDJ69731.1 - 6.4 5.5 5.6 31 3.2 0.0 2.2 2 0 0 2 2 2 0 Otopetrin FAD_binding_3 PF01494.19 CDJ69733.1 - 8.9e-22 77.8 3.7 2.7e-13 49.9 0.4 4.5 5 0 0 5 5 5 3 FAD binding domain DUF677 PF05055.12 CDJ69734.1 - 0.00069 18.6 2.9 0.00069 18.6 2.9 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF677) Spt20 PF12090.8 CDJ69734.1 - 0.057 13.0 13.3 0.066 12.8 13.3 1.2 1 0 0 1 1 1 0 Spt20 family PBP PF01161.20 CDJ69734.1 - 5.5 7.3 7.1 14 6.0 7.1 1.8 1 1 0 1 1 1 0 Phosphatidylethanolamine-binding protein Trehalose_PPase PF02358.16 CDJ69737.1 - 4.3e-08 32.6 0.7 8e-08 31.7 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase NAD_binding_1 PF00175.21 CDJ69738.1 - 1.3e-13 51.5 6.4 3.6e-11 43.7 1.9 2.8 2 1 0 2 2 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CDJ69738.1 - 1.5e-07 31.7 0.2 1.3e-06 28.6 0.0 2.2 2 1 0 2 2 2 1 Ferric reductase NAD binding domain RskA PF10099.9 CDJ69738.1 - 1.3e-05 25.6 14.7 0.0063 16.8 0.1 3.5 3 1 0 3 3 3 2 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ69738.1 - 0.006 17.5 7.3 0.73 10.8 2.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ69738.1 - 0.032 14.2 32.4 0.12 12.4 15.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rpb1_3 PF04983.18 CDJ69738.1 - 0.039 13.9 0.5 0.065 13.2 0.5 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 DUF3408 PF11888.8 CDJ69738.1 - 0.044 13.9 8.6 0.065 13.4 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Ctr PF04145.15 CDJ69738.1 - 0.059 14.0 0.9 7.1 7.2 0.1 2.3 2 0 0 2 2 2 0 Ctr copper transporter family DUF2722 PF10846.8 CDJ69738.1 - 0.07 12.1 27.5 0.084 11.8 10.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SRP9-21 PF05486.12 CDJ69738.1 - 0.076 13.4 2.6 1.3 9.5 0.3 2.4 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) PepSY_TM PF03929.16 CDJ69738.1 - 0.094 12.4 5.9 0.22 11.2 1.1 2.9 3 0 0 3 3 3 0 PepSY-associated TM region Peroxin-13_N PF04088.13 CDJ69738.1 - 0.15 12.3 1.7 1.4 9.2 0.6 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region SAE2 PF08573.10 CDJ69738.1 - 0.24 12.5 6.5 0.51 11.5 0.7 2.5 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Med15 PF09606.10 CDJ69738.1 - 0.41 9.3 30.1 0.39 9.3 14.8 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1115 PF06544.12 CDJ69738.1 - 0.64 10.1 7.4 0.11 12.6 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) Hydin_ADK PF17213.3 CDJ69738.1 - 0.77 10.0 6.8 1.9 8.7 0.9 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain CAF1 PF04857.20 CDJ69738.1 - 0.99 8.5 8.2 2.2e+02 0.8 14.0 1.7 1 1 0 1 1 1 0 CAF1 family ribonuclease Peptidase_S49_N PF08496.10 CDJ69738.1 - 1 9.4 8.2 6.8 6.7 5.4 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PRC2_HTH_1 PF18118.1 CDJ69738.1 - 2 9.2 6.0 1.1 10.1 0.7 2.3 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain SpoIIP PF07454.11 CDJ69738.1 - 2.3 7.6 7.5 0.63 9.4 1.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) EIIBC-GUT_N PF03612.14 CDJ69738.1 - 2.7 7.7 8.0 1.6 8.4 2.4 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus CDRT4 PF15213.6 CDJ69738.1 - 2.8 8.5 4.3 8.6 7.0 1.2 2.2 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein AAA_23 PF13476.6 CDJ69738.1 - 3.4 8.1 11.6 0.82 10.1 5.0 2.0 2 0 0 2 2 2 0 AAA domain Mak10 PF04112.13 CDJ69738.1 - 3.6 7.1 6.4 1.9 8.0 1.1 2.2 2 0 0 2 2 2 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Dopey_N PF04118.14 CDJ69738.1 - 4.1 6.4 11.6 0.086 11.9 1.4 2.4 2 1 0 2 2 2 0 Dopey, N-terminal Spt20 PF12090.8 CDJ69738.1 - 4.6 6.8 45.7 2.6 7.6 22.6 2.2 2 0 0 2 2 2 0 Spt20 family Gastrin PF00918.17 CDJ69738.1 - 4.8 8.2 12.0 4.6 8.2 5.2 2.5 2 0 0 2 2 2 0 Gastrin/cholecystokinin family DUF5327 PF17261.2 CDJ69738.1 - 5.1 7.9 19.4 4.7 8.0 0.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) WASH-7_C PF14746.6 CDJ69738.1 - 5.5 6.6 17.1 3.6 7.2 8.2 2.2 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal DUF2681 PF10883.8 CDJ69738.1 - 8.1 6.9 28.5 0.23 11.9 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) MAS20 PF02064.15 CDJ69738.1 - 9 6.4 17.6 0.076 13.1 3.3 2.7 3 0 0 3 3 2 0 MAS20 protein import receptor DUF3984 PF13136.6 CDJ69738.1 - 9.6 5.5 10.1 7.8 5.8 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) NAD_kinase PF01513.21 CDJ69739.1 - 0.0084 15.3 4.9 0.49 9.5 0.0 3.1 4 0 0 4 4 4 2 ATP-NAD kinase CCSAP PF15748.5 CDJ69739.1 - 0.18 11.9 30.2 0.049 13.8 9.3 2.5 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated DAGK_cat PF00781.24 CDJ69739.1 - 0.33 10.6 0.0 0.33 10.6 0.0 2.6 3 0 0 3 3 1 0 Diacylglycerol kinase catalytic domain Neur_chan_memb PF02932.16 CDJ69739.1 - 0.39 10.7 17.2 1.9 8.5 1.6 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BORG_CEP PF14957.6 CDJ69739.1 - 0.93 10.7 14.8 6.1 8.0 5.5 2.6 2 0 0 2 2 2 0 Cdc42 effector EPL1 PF10513.9 CDJ69739.1 - 1.6 9.1 21.7 3.3 8.1 9.3 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Exonuc_VII_L PF02601.15 CDJ69739.1 - 2.4 7.6 20.2 0.74 9.3 0.8 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit PTPRCAP PF15713.5 CDJ69739.1 - 2.7 8.3 26.6 5.8 7.2 10.3 2.7 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF702 PF05142.12 CDJ69739.1 - 3.3 8.2 21.3 5.7 7.4 7.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Lin-8 PF03353.15 CDJ69739.1 - 4.9 6.6 27.2 2.9 7.4 12.7 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist MMR1 PF08505.10 CDJ69739.1 - 5.6 7.2 27.6 5.4 7.2 12.0 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein NARP1 PF12569.8 CDJ69739.1 - 7.2 5.4 28.4 0.022 13.7 7.1 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF3523 PF12037.8 CDJ69739.1 - 9.9 5.4 40.9 1 8.7 9.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) ATP-synt PF00231.19 CDJ69740.1 - 3.7e-05 23.6 6.2 3.7e-05 23.6 6.2 1.8 1 1 1 2 2 1 1 ATP synthase DUF4834 PF16118.5 CDJ69740.1 - 0.0044 17.9 15.3 0.31 12.0 8.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ69740.1 - 0.018 13.9 13.0 0.021 13.6 13.0 1.1 1 0 0 1 1 1 0 Presenilin Ctr PF04145.15 CDJ69740.1 - 0.018 15.7 4.7 0.018 15.7 4.7 2.0 1 1 1 2 2 2 0 Ctr copper transporter family EIIBC-GUT_N PF03612.14 CDJ69740.1 - 0.027 14.2 16.9 0.18 11.5 0.4 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus UPF0239 PF06783.11 CDJ69740.1 - 0.15 12.2 6.6 1.1 9.5 3.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) Zip PF02535.22 CDJ69740.1 - 0.16 11.1 0.3 0.2 10.9 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CDJ69740.1 - 0.92 9.5 11.5 1.1 9.2 11.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AIF_C PF14721.6 CDJ69740.1 - 2.6 8.4 13.8 6.3 7.2 8.0 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term HA2 PF04408.23 CDJ69740.1 - 3.2 8.1 9.8 9.6 6.5 5.1 2.1 2 0 0 2 2 2 0 Helicase associated domain (HA2) DUF1980 PF09323.10 CDJ69740.1 - 3.3 7.6 17.3 4.9 7.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) OSTbeta PF15048.6 CDJ69740.1 - 3.3 7.9 11.0 2.6 8.2 7.0 2.0 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Glt_symporter PF03616.14 CDJ69740.1 - 4.4 5.9 8.3 0.13 10.9 1.4 1.8 1 1 1 2 2 2 0 Sodium/glutamate symporter O-antigen_lig PF13425.6 CDJ69740.1 - 5.5 5.7 6.2 6.5 5.4 6.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Orf78 PF06024.12 CDJ69740.1 - 5.7 7.3 11.6 30 5.0 7.8 2.1 2 0 0 2 2 2 0 Orf78 (ac78) PUCC PF03209.15 CDJ69740.1 - 7.8 5.4 13.5 6.9 5.6 0.9 2.0 1 1 0 2 2 2 0 PUCC protein SID-1_RNA_chan PF13965.6 CDJ69740.1 - 8.8 4.6 9.7 20 3.4 10.0 1.5 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 MLANA PF14991.6 CDJ69740.1 - 8.9 6.6 9.5 23 5.3 0.2 2.1 2 0 0 2 2 2 0 Protein melan-A SDA1 PF05285.12 CDJ69741.1 - 0.0005 19.6 16.3 0.0005 19.6 16.3 2.0 2 0 0 2 2 2 1 SDA1 Caldesmon PF02029.15 CDJ69741.1 - 0.0014 17.5 27.9 0.0014 17.5 27.9 1.7 2 0 0 2 2 2 1 Caldesmon PNISR PF15996.5 CDJ69741.1 - 0.0028 18.0 36.3 0.0028 18.0 36.3 2.6 3 0 0 3 3 3 1 Arginine/serine-rich protein PNISR Ndc1_Nup PF09531.10 CDJ69741.1 - 1.7 7.2 35.9 0.7 8.5 27.1 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Raftlin PF15250.6 CDJ69741.1 - 2 7.0 26.4 0.04 12.7 19.4 1.7 2 0 0 2 2 2 0 Raftlin Thioredoxin PF00085.20 CDJ69742.1 - 8e-12 45.1 0.0 9.6e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 CDJ69742.1 - 0.0013 18.5 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CDJ69742.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family SNF2_N PF00176.23 CDJ69743.1 - 7.6e-16 57.8 7.5 2.2e-09 36.5 0.0 3.1 3 0 0 3 3 3 2 SNF2 family N-terminal domain IMUP PF15761.5 CDJ69743.1 - 0.032 14.9 4.6 0.032 14.9 4.6 5.2 5 1 0 5 5 5 0 Immortalisation up-regulated protein SART-1 PF03343.13 CDJ69743.1 - 0.45 9.0 23.3 0.86 8.1 23.3 1.4 1 0 0 1 1 1 0 SART-1 family Connexin PF00029.19 CDJ69743.1 - 2.1 8.1 13.1 0.22 11.2 7.6 2.0 2 0 0 2 2 2 0 Connexin 2OG-FeII_Oxy_5 PF13759.6 CDJ69743.1 - 4.1 7.9 9.2 3.7 8.0 5.6 2.4 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Folate_carrier PF01770.18 CDJ69743.1 - 7.8 5.1 6.8 18 3.9 6.8 1.6 1 0 0 1 1 1 0 Reduced folate carrier BshC PF10079.9 CDJ69744.1 - 0.09 11.5 8.5 0.1 11.3 8.5 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Spore_coat_CotO PF14153.6 CDJ69744.1 - 1.6 8.7 11.7 2 8.3 11.7 1.0 1 0 0 1 1 1 0 Spore coat protein CotO MBR1 PF17058.5 CDJ69745.1 - 5.9 7.1 22.3 7 6.9 22.3 1.1 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 SUIM_assoc PF16619.5 CDJ69746.1 - 0.0027 17.7 2.5 0.0066 16.5 0.2 2.1 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 CDJ69746.1 - 0.68 9.1 8.4 0.86 8.7 8.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RRM_1 PF00076.22 CDJ69747.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT_EZ PF13513.6 CDJ69748.1 - 3.8e-07 30.5 1.7 3.8e-07 30.5 1.7 6.8 5 2 3 8 8 8 1 HEAT-like repeat DUF2722 PF10846.8 CDJ69748.1 - 3.7e-05 22.9 5.6 3.7e-05 22.9 5.6 4.1 4 0 0 4 4 4 3 Protein of unknown function (DUF2722) HEAT PF02985.22 CDJ69748.1 - 0.0002 21.4 0.1 0.0002 21.4 0.1 4.2 4 0 0 4 4 3 1 HEAT repeat RskA PF10099.9 CDJ69748.1 - 0.0037 17.6 12.4 0.0037 17.6 12.4 4.2 2 2 1 3 3 2 1 Anti-sigma-K factor rskA RICTOR_N PF14664.6 CDJ69748.1 - 0.011 14.8 3.0 1.2 8.0 0.1 3.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term DUF4050 PF13259.6 CDJ69748.1 - 0.012 16.0 6.3 0.012 16.0 6.3 3.0 2 2 0 2 2 1 0 Protein of unknown function (DUF4050) HEAT_2 PF13646.6 CDJ69748.1 - 0.014 15.7 0.1 0.014 15.7 0.1 4.1 3 1 1 4 4 4 0 HEAT repeats PIP5K PF01504.18 CDJ69748.1 - 0.1 11.8 0.1 0.1 11.8 0.1 2.3 2 1 0 2 2 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF1824 PF08854.10 CDJ69748.1 - 0.11 12.4 0.3 0.11 12.4 0.3 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF1824) DUF4366 PF14283.6 CDJ69748.1 - 0.85 9.7 8.5 2 8.4 0.7 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4366) Transglut_prok PF09017.10 CDJ69748.1 - 2 7.6 9.7 5.3 6.3 0.0 2.5 2 1 0 2 2 2 0 Microbial transglutaminase Spt20 PF12090.8 CDJ69748.1 - 3.2 7.3 73.9 0.22 11.1 5.6 4.2 4 0 0 4 4 4 0 Spt20 family DUF4834 PF16118.5 CDJ69748.1 - 3.5 8.7 24.5 0.049 14.6 3.3 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) SbcCD_C PF13558.6 CDJ69748.1 - 4.6 7.5 8.9 10 6.4 1.4 3.6 3 1 1 4 4 3 0 Putative exonuclease SbcCD, C subunit Eapp_C PF10238.9 CDJ69748.1 - 5.7 7.0 14.9 0.057 13.5 0.6 3.7 4 0 0 4 4 4 0 E2F-associated phosphoprotein Connexin PF00029.19 CDJ69748.1 - 8.1 6.1 7.0 0.86 9.3 0.0 2.7 4 0 0 4 4 4 0 Connexin CPSF100_C PF13299.6 CDJ69748.1 - 8.4 6.5 11.5 0.86 9.8 0.4 3.7 4 0 0 4 4 4 0 Cleavage and polyadenylation factor 2 C-terminal Pet20 PF08692.10 CDJ69748.1 - 10 6.9 10.1 25 5.6 0.0 3.4 4 0 0 4 4 3 0 Mitochondrial protein Pet20 RRM_1 PF00076.22 CDJ69749.1 - 2.8e-11 43.1 0.8 3.1e-11 42.9 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 CDJ69749.1 - 0.014 15.3 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) DUF4701 PF15773.5 CDJ69749.1 - 0.021 13.9 0.0 0.021 13.9 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4701) RNA_bind PF08675.11 CDJ69749.1 - 0.042 13.9 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain SR-25 PF10500.9 CDJ69749.1 - 0.15 11.6 3.0 0.21 11.2 3.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_7 PF16367.5 CDJ69749.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ69749.1 - 0.2 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3974 PF13120.6 CDJ69749.1 - 0.3 11.2 2.5 30 4.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) DUF4131 PF13567.6 CDJ69749.1 - 0.37 10.4 6.8 0.66 9.6 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Utp14 PF04615.13 CDJ69750.1 - 3.2 6.2 60.7 4.4 5.7 60.7 1.1 1 0 0 1 1 1 0 Utp14 protein RAP1 PF07218.11 CDJ69750.1 - 7.6 4.7 15.2 14 3.8 15.2 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ69751.1 - 0.0011 18.7 12.3 0.0011 18.6 12.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF1117 PF06547.12 CDJ69751.1 - 0.018 15.6 1.3 0.028 15.0 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) DUF3123 PF11321.8 CDJ69751.1 - 0.08 13.6 0.7 0.091 13.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Lin-8 PF03353.15 CDJ69751.1 - 0.46 10.0 2.1 0.47 10.0 2.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF755 PF05501.11 CDJ69751.1 - 1.3 9.3 18.2 2.2 8.6 18.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Herpes_pp85 PF04637.12 CDJ69751.1 - 1.5 7.1 4.9 1.5 7.1 4.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Syntaphilin PF15290.6 CDJ69751.1 - 1.7 8.2 8.7 2.1 7.9 8.7 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp IMUP PF15761.5 CDJ69751.1 - 2.6 8.8 14.6 0.47 11.2 11.4 1.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein Med3 PF11593.8 CDJ69752.1 - 0.0011 18.2 12.1 0.0013 18.0 12.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal SR-25 PF10500.9 CDJ69752.1 - 0.0019 17.9 9.5 0.0024 17.5 9.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ69752.1 - 0.0068 16.0 8.1 0.0068 16.0 8.1 1.1 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ69752.1 - 0.17 11.9 8.7 0.17 11.8 8.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK2AP PF09806.9 CDJ69752.1 - 0.18 11.9 7.4 0.22 11.6 7.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Pex14_N PF04695.13 CDJ69752.1 - 0.2 12.3 8.5 0.22 12.2 8.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2201_N PF13203.6 CDJ69752.1 - 0.5 9.9 7.4 0.62 9.6 7.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4551 PF15087.6 CDJ69752.1 - 1.6 7.5 7.6 1.8 7.3 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF1180 PF06679.12 CDJ69752.1 - 3.9 7.8 7.8 4.8 7.6 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Presenilin PF01080.17 CDJ69752.1 - 4.7 5.9 5.6 5.1 5.7 5.6 1.0 1 0 0 1 1 1 0 Presenilin DUF3626 PF12294.8 CDJ69755.1 - 2.1e-08 33.6 0.1 0.00033 19.8 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3626) Ribosomal_S17_N PF16205.5 CDJ69755.1 - 0.18 12.2 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal Pkinase PF00069.25 CDJ69756.1 - 2.6e-25 89.3 0.0 3.2e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ69756.1 - 2.5e-16 59.7 0.0 3.1e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ69756.1 - 3.3e-08 32.7 0.0 4.2e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CDJ69756.1 - 0.063 12.2 0.5 0.12 11.3 0.1 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.23 CDJ69756.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GST_C_3 PF14497.6 CDJ69760.1 - 0.018 15.2 0.1 0.14 12.3 0.1 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF5486 PF17588.2 CDJ69761.1 - 0.63 10.0 3.0 0.95 9.4 3.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5486) AP2 PF00847.20 CDJ69763.1 - 0.05 13.8 1.5 0.11 12.7 1.5 1.5 1 0 0 1 1 1 0 AP2 domain DPM3 PF08285.11 CDJ69766.1 - 4.6 7.5 6.5 0.65 10.2 0.2 2.8 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) SPX PF03105.19 CDJ69768.1 - 0.0026 17.8 18.2 0.0081 16.1 18.2 1.8 1 0 0 1 1 1 1 SPX domain IQ PF00612.27 CDJ69768.1 - 0.01 15.6 0.0 0.036 13.8 0.0 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif GPS2_interact PF15784.5 CDJ69768.1 - 0.01 16.3 3.5 0.01 16.3 3.5 3.1 3 1 1 4 4 4 0 G-protein pathway suppressor 2-interacting domain PI_PP_I PF18363.1 CDJ69768.1 - 0.22 11.7 1.6 2 8.6 1.1 2.6 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Hydantoinase_B PF02538.14 CDJ69768.1 - 2.2 6.6 4.7 3.9 5.8 4.7 1.4 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase DUF4618 PF15397.6 CDJ69768.1 - 3.7 6.9 29.1 2 7.7 8.0 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4618) Beta-Casp PF10996.8 CDJ69770.1 - 0.0018 18.6 0.0 0.0065 16.7 0.0 2.0 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CDJ69770.1 - 0.047 13.1 0.0 0.41 10.0 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain SPX PF03105.19 CDJ69770.1 - 0.073 13.0 17.4 0.057 13.3 12.9 2.3 2 0 0 2 2 2 0 SPX domain SpoIIIAH PF12685.7 CDJ69770.1 - 4.5 7.0 13.1 34 4.2 0.1 3.8 3 0 0 3 3 3 0 SpoIIIAH-like protein Tmemb_14 PF03647.13 CDJ69771.1 - 4e-06 27.5 5.5 4e-06 27.5 5.5 2.0 2 0 0 2 2 2 1 Transmembrane proteins 14C FAD-oxidase_C PF02913.19 CDJ69772.1 - 2e-36 125.9 0.0 4.1e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CDJ69772.1 - 2.4e-35 121.3 0.3 4.4e-35 120.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CDJ69772.1 - 0.072 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Androgen_recep PF02166.16 CDJ69772.1 - 5.3 5.8 14.2 7.6 5.3 14.2 1.2 1 0 0 1 1 1 0 Androgen receptor S-AdoMet_synt_C PF02773.16 CDJ69773.1 - 5.2e-62 207.9 0.0 1.6e-61 206.3 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CDJ69773.1 - 1.8e-47 160.5 0.0 3.4e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CDJ69773.1 - 8e-44 148.4 0.2 1.7e-43 147.3 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain CxC2 PF18803.1 CDJ69774.1 - 0.034 14.3 0.1 0.13 12.4 0.1 2.0 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases RAP1 PF07218.11 CDJ69774.1 - 2.4 6.3 3.7 5 5.3 3.7 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Maf1 PF09174.10 CDJ69775.1 - 0.02 15.1 1.3 0.02 15.1 1.3 2.8 2 1 0 2 2 2 0 Maf1 regulator BCD PF15461.6 CDJ69775.1 - 0.4 10.1 4.8 0.31 10.5 1.4 2.3 2 0 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase AAA_18 PF13238.6 CDJ69775.1 - 0.42 11.2 1.3 1.9 9.0 1.2 2.1 2 0 0 2 2 2 0 AAA domain CCDC53 PF10152.9 CDJ69775.1 - 1.8 9.0 25.6 6.2 7.2 5.4 3.3 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex EIIBC-GUT_N PF03612.14 CDJ69775.1 - 6.5 6.5 14.4 3.1 7.5 5.6 3.3 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus AIF_C PF14721.6 CDJ69775.1 - 7.8 6.9 12.4 6.1 7.2 4.4 3.3 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Tcf25 PF04910.14 CDJ69776.1 - 0.0041 16.2 0.6 0.0049 16.0 0.6 1.2 1 1 0 1 1 1 1 Transcriptional repressor TCF25 VirE2 PF07229.12 CDJ69776.1 - 0.0097 14.6 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 1 VirE2 dCache_1 PF02743.18 CDJ69776.1 - 0.044 13.6 4.3 0.13 12.0 0.1 2.2 2 0 0 2 2 2 0 Cache domain SUIM_assoc PF16619.5 CDJ69776.1 - 0.57 10.3 11.7 0.39 10.8 4.7 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1043 PF06295.12 CDJ69776.1 - 2.2 8.3 10.9 0.25 11.4 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) SHR3_chaperone PF08229.11 CDJ69777.1 - 0.29 10.1 0.7 0.43 9.5 0.7 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 AP2 PF00847.20 CDJ69778.1 - 6.5e-10 39.1 7.2 6.5e-10 39.1 7.2 5.4 6 1 0 6 6 6 2 AP2 domain ACDC PF14733.6 CDJ69778.1 - 0.00054 20.2 0.1 0.00054 20.2 0.1 2.1 2 0 0 2 2 2 1 AP2-coincident C-terminal Lin-8 PF03353.15 CDJ69778.1 - 0.64 9.5 22.8 0.04 13.5 10.1 3.1 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist Mg_trans_NIPA PF05653.14 CDJ69779.1 - 4.9e-13 48.8 5.7 6e-13 48.6 5.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CDJ69779.1 - 4.2e-06 27.0 6.1 4.2e-06 27.0 6.1 2.2 2 1 0 2 2 2 1 EamA-like transporter family DUF4179 PF13786.6 CDJ69780.1 - 0.014 15.8 0.1 0.52 10.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) SR-25 PF10500.9 CDJ69780.1 - 0.3 10.7 28.3 0.4 10.2 27.7 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ69780.1 - 1.7 8.6 35.0 2.4 8.1 35.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RCC1 PF00415.18 CDJ69783.1 - 1.3e-39 134.6 21.7 2.9e-11 43.8 0.1 9.1 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ69783.1 - 1.6e-06 27.7 52.8 0.0086 15.9 1.2 9.6 9 1 0 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat Sin_N PF04801.13 CDJ69783.1 - 0.015 14.5 0.5 0.035 13.3 0.5 1.5 1 0 0 1 1 1 0 Sin-like protein conserved region Efg1 PF10153.9 CDJ69783.1 - 0.026 14.9 1.3 0.093 13.1 0.1 2.4 2 0 0 2 2 2 0 rRNA-processing protein Efg1 TFIIA PF03153.13 CDJ69783.1 - 0.25 11.3 21.1 0.012 15.7 4.8 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ69783.1 - 0.36 11.1 56.8 0.058 13.7 10.5 6.2 6 0 0 6 6 6 0 Anti-sigma-K factor rskA UPRTase PF14681.6 CDJ69785.1 - 3.5e-56 189.9 0.4 1.4e-54 184.7 0.0 2.2 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CDJ69785.1 - 4.5e-07 29.5 0.0 1.2e-06 28.1 0.0 1.5 1 1 0 2 2 2 1 Phosphoribosyl transferase domain EF-hand_13 PF17958.1 CDJ69785.1 - 0.0017 18.1 0.0 0.3 10.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Spt20 PF12090.8 CDJ69786.1 - 0.00011 21.9 12.7 0.00011 21.9 12.7 1.9 2 0 0 2 2 2 1 Spt20 family FAM176 PF14851.6 CDJ69786.1 - 0.0003 20.5 1.1 0.061 13.0 0.2 2.3 2 0 0 2 2 2 1 FAM176 family SPX PF03105.19 CDJ69786.1 - 0.0012 18.8 4.4 0.0018 18.2 4.4 1.3 1 0 0 1 1 1 1 SPX domain DUF4834 PF16118.5 CDJ69786.1 - 0.018 16.0 3.7 0.018 16.0 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Med15 PF09606.10 CDJ69786.1 - 0.029 13.1 22.2 0.053 12.2 22.2 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.16 CDJ69786.1 - 0.034 14.2 1.8 0.29 11.2 0.7 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Folate_carrier PF01770.18 CDJ69786.1 - 0.13 11.0 2.1 0.27 9.9 2.1 1.4 1 0 0 1 1 1 0 Reduced folate carrier DUF4220 PF13968.6 CDJ69786.1 - 0.21 11.0 2.3 0.14 11.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) Nha1_C PF08619.10 CDJ69786.1 - 0.24 10.6 14.1 0.19 10.9 0.1 2.4 3 0 0 3 3 3 0 Alkali metal cation/H+ antiporter Nha1 C terminus TMEM51 PF15345.6 CDJ69786.1 - 0.24 11.2 14.2 1.2 8.9 4.9 3.3 2 1 0 2 2 2 0 Transmembrane protein 51 eIF-3_zeta PF05091.12 CDJ69786.1 - 0.26 10.2 6.4 0.4 9.6 6.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ69786.1 - 0.37 8.7 3.1 1.2 6.9 2.1 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Orf78 PF06024.12 CDJ69786.1 - 0.67 10.3 2.1 22 5.4 1.7 2.7 3 0 0 3 3 2 0 Orf78 (ac78) CLN3 PF02487.17 CDJ69786.1 - 0.78 8.7 6.9 0.029 13.4 0.8 1.6 2 0 0 2 2 1 0 CLN3 protein EPL1 PF10513.9 CDJ69786.1 - 1.1 9.6 6.9 1.1 9.7 4.0 1.9 2 0 0 2 2 2 0 Enhancer of polycomb-like SR-25 PF10500.9 CDJ69786.1 - 2.4 7.7 36.1 2.7 7.5 19.4 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4820 PF16091.5 CDJ69786.1 - 2.5 7.4 9.2 0.43 9.9 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) BAF1_ABF1 PF04684.13 CDJ69786.1 - 2.6 7.0 13.2 2.8 6.9 2.9 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF719 PF05334.13 CDJ69786.1 - 3.1 8.0 9.3 0.34 11.1 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) GREB1 PF15782.5 CDJ69786.1 - 3.2 4.8 12.1 2.2 5.3 4.1 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer DUF2973 PF11189.8 CDJ69786.1 - 3.7 7.7 4.8 0.93 9.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) SRP-alpha_N PF04086.13 CDJ69786.1 - 4.9 7.0 14.4 6 6.7 0.4 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal XRCC4 PF06632.12 CDJ69786.1 - 5.5 5.7 16.8 5.7 5.7 0.8 2.1 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RR_TM4-6 PF06459.12 CDJ69786.1 - 6.3 6.5 8.1 0.71 9.6 1.8 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 CDJ69786.1 - 7 6.5 14.8 1.3 8.9 8.9 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF5327 PF17261.2 CDJ69786.1 - 8.4 7.2 15.7 0.46 11.3 5.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DnaJ PF00226.31 CDJ69788.1 - 1.9e-05 24.7 1.1 3e-05 24.1 0.1 1.8 2 0 0 2 2 1 1 DnaJ domain PNISR PF15996.5 CDJ69788.1 - 0.0011 19.3 10.9 0.0014 18.9 10.9 1.1 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR SR-25 PF10500.9 CDJ69788.1 - 0.0055 16.4 27.5 0.0055 16.4 27.5 1.9 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Tir_receptor_N PF07490.11 CDJ69788.1 - 0.0077 16.1 1.4 0.013 15.4 1.4 1.3 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) N-terminus DUF2967 PF11179.8 CDJ69788.1 - 0.025 12.7 20.9 0.04 12.0 20.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) ANAPC_CDC26 PF10471.9 CDJ69788.1 - 0.04 14.7 15.0 0.04 14.7 15.0 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Med15 PF09606.10 CDJ69788.1 - 0.07 11.8 19.1 0.079 11.6 19.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CytochromB561_N PF09786.9 CDJ69788.1 - 0.095 11.7 10.7 0.11 11.5 10.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal TFIIA PF03153.13 CDJ69788.1 - 0.13 12.2 23.2 0.15 12.0 23.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 CDJ69788.1 - 0.14 11.8 10.2 0.2 11.3 10.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GREB1 PF15782.5 CDJ69788.1 - 0.17 8.9 16.8 0.2 8.8 16.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF572 PF04502.13 CDJ69788.1 - 0.31 10.6 11.5 0.38 10.3 11.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.16 CDJ69788.1 - 0.34 10.9 8.5 0.46 10.5 8.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF515 PF04415.12 CDJ69788.1 - 0.37 9.1 7.2 0.5 8.7 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RAP1 PF07218.11 CDJ69788.1 - 0.38 9.0 8.7 0.47 8.7 8.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SPX PF03105.19 CDJ69788.1 - 0.41 10.5 13.5 0.45 10.4 13.5 1.1 1 0 0 1 1 1 0 SPX domain Peroxin-3 PF04882.12 CDJ69788.1 - 0.61 9.0 13.0 0.79 8.6 13.0 1.1 1 0 0 1 1 1 0 Peroxin-3 DUF755 PF05501.11 CDJ69788.1 - 0.8 10.0 26.8 0.41 10.9 22.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Ribosomal_60s PF00428.19 CDJ69788.1 - 0.94 10.1 8.6 0.078 13.6 2.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein V_ATPase_I PF01496.19 CDJ69788.1 - 1.2 7.0 4.2 1.4 6.8 4.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Miga PF10265.9 CDJ69788.1 - 1.8 7.4 14.3 2.3 7.1 13.9 1.4 1 1 0 1 1 1 0 Mitoguardin Peptidase_S64 PF08192.11 CDJ69788.1 - 1.9 6.9 12.3 2.1 6.7 12.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Myc_N PF01056.18 CDJ69788.1 - 3.1 7.6 14.7 4.3 7.1 14.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Presenilin PF01080.17 CDJ69788.1 - 3.7 6.2 13.7 5.2 5.7 13.7 1.3 1 0 0 1 1 1 0 Presenilin PAP1 PF08601.10 CDJ69788.1 - 5.8 6.5 19.2 8.2 6.0 19.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Hid1 PF12722.7 CDJ69788.1 - 7.5 4.5 11.5 8.2 4.4 11.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.6 CDJ69788.1 - 8.1 5.7 15.7 11 5.3 15.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SPT16 PF08644.11 CDJ69789.1 - 2.3e-41 141.5 0.0 2.3e-41 141.5 0.0 3.2 2 1 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) WD40 PF00400.32 CDJ69789.1 - 9e-25 86.5 6.0 4.7e-07 30.4 0.0 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat FACT-Spt16_Nlob PF14826.6 CDJ69789.1 - 2.5e-14 53.4 0.1 1.6e-13 50.8 0.0 2.5 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.12 CDJ69789.1 - 3.4e-12 46.6 0.0 1.3e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.24 CDJ69789.1 - 5e-12 45.9 2.9 3.4e-07 30.2 0.0 3.7 2 2 1 3 3 3 2 Metallopeptidase family M24 ANAPC4_WD40 PF12894.7 CDJ69789.1 - 2e-08 34.4 0.0 0.089 13.1 0.0 5.2 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ69789.1 - 2e-07 30.3 0.1 0.028 13.4 0.0 3.4 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ69789.1 - 0.0016 17.2 0.1 1.1 7.8 0.0 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Methyltransf_16 PF10294.9 CDJ69793.1 - 7.8e-06 25.7 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase SR-25 PF10500.9 CDJ69794.1 - 0.0003 20.5 8.9 0.0003 20.5 8.9 6.7 7 0 0 7 7 7 1 Nuclear RNA-splicing-associated protein DUF4667 PF15700.5 CDJ69794.1 - 0.00087 19.5 9.7 0.00087 19.5 9.7 5.8 2 1 2 5 5 5 1 Domain of unknown function (DUF4667) Med15 PF09606.10 CDJ69794.1 - 0.0033 16.2 22.9 0.0033 16.2 22.9 4.3 3 1 0 4 4 4 1 ARC105 or Med15 subunit of Mediator complex non-fungal SpoIIP PF07454.11 CDJ69794.1 - 0.0041 16.6 7.9 0.0041 16.6 7.9 6.4 5 2 0 5 5 5 1 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 CDJ69794.1 - 0.0057 16.7 27.8 0.0057 16.7 27.8 5.6 4 1 1 6 6 6 4 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ69794.1 - 0.0086 16.2 7.7 0.0086 16.2 7.7 4.6 3 1 1 4 4 4 2 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 CDJ69794.1 - 0.012 15.6 1.9 0.012 15.6 1.9 5.5 4 1 0 4 4 4 0 N-glycosylation protein DUF2722 PF10846.8 CDJ69794.1 - 0.013 14.4 0.0 0.013 14.4 0.0 8.2 5 3 1 6 6 6 0 Protein of unknown function (DUF2722) Zip PF02535.22 CDJ69794.1 - 0.016 14.5 0.4 0.016 14.5 0.4 4.0 4 1 0 4 4 4 0 ZIP Zinc transporter Collagen PF01391.18 CDJ69795.1 - 0.0002 21.0 9.3 0.00035 20.3 9.3 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) GET2 PF08690.10 CDJ69795.1 - 0.14 11.8 1.5 0.18 11.4 1.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIA PF03153.13 CDJ69795.1 - 0.14 12.1 7.0 0.18 11.8 7.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ69795.1 - 0.36 10.9 14.9 0.64 10.1 0.6 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Suf PF05843.14 CDJ69795.1 - 5.4 6.9 6.8 13 5.7 7.1 1.5 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) ThiF PF00899.21 CDJ69796.1 - 3.6e-22 78.9 10.2 1.8e-20 73.4 1.3 4.1 2 1 3 5 5 5 2 ThiF family Rhodanese PF00581.20 CDJ69796.1 - 0.0084 16.6 0.0 0.1 13.1 0.0 2.7 2 1 0 2 2 2 1 Rhodanese-like domain SR-25 PF10500.9 CDJ69796.1 - 0.15 11.6 15.1 0.33 10.5 15.1 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ69796.1 - 2.7 6.0 14.8 3.9 5.4 14.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDC45 PF02724.14 CDJ69796.1 - 4.3 5.5 7.3 15 3.7 6.9 1.8 1 1 0 1 1 1 0 CDC45-like protein DUF4064 PF13273.6 CDJ69796.1 - 4.9 7.5 11.8 18 5.7 11.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) SARAF PF06682.12 CDJ69796.1 - 6.7 6.3 7.7 3.3 7.3 2.9 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Cupin_8 PF13621.6 CDJ69797.1 - 3.8e-31 108.7 0.0 8.8e-27 94.4 0.0 2.2 1 1 1 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 CDJ69797.1 - 9.2e-10 38.5 0.1 5.9e-06 26.0 0.0 3.4 4 0 0 4 4 4 2 Cupin superfamily protein Collagen PF01391.18 CDJ69797.1 - 1.4e-06 27.9 78.4 0.00024 20.8 33.6 3.7 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Ribosomal_60s PF00428.19 CDJ69797.1 - 0.0012 19.4 7.7 0.0012 19.4 7.7 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein JmjC PF02373.22 CDJ69797.1 - 0.0036 17.7 1.6 0.015 15.7 0.0 2.5 2 1 0 2 2 2 1 JmjC domain, hydroxylase Activator_LAG-3 PF11498.8 CDJ69797.1 - 0.04 12.9 13.9 0.086 11.8 13.9 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3573 PF12097.8 CDJ69797.1 - 0.43 9.4 1.9 0.64 8.8 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Serine_rich PF08824.10 CDJ69797.1 - 1.1 9.2 9.5 0.19 11.7 3.7 2.0 2 0 0 2 2 2 0 Serine rich protein interaction domain IMUP PF15761.5 CDJ69797.1 - 5.2 7.8 19.8 2.6 8.8 10.5 3.0 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF1635 PF07795.11 CDJ69797.1 - 10 5.9 16.1 0.26 11.1 3.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) NST1 PF13945.6 CDJ69798.1 - 0.7 10.0 10.3 0.79 9.8 10.3 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Band_3_cyto PF07565.13 CDJ69798.1 - 5.3 6.8 7.0 5.6 6.7 7.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spt20 PF12090.8 CDJ69799.1 - 0.15 11.7 1.7 0.22 11.1 1.7 1.1 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ69799.1 - 0.15 11.7 13.3 0.2 11.2 13.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SDP_N PF12278.8 CDJ69799.1 - 0.18 11.9 3.6 0.28 11.3 3.6 1.2 1 0 0 1 1 1 0 Sex determination protein N terminal GREB1 PF15782.5 CDJ69799.1 - 0.77 6.8 5.2 0.89 6.6 5.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1180 PF06679.12 CDJ69799.1 - 1.1 9.6 7.7 2.1 8.7 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 CDJ69799.1 - 3.8 6.0 6.9 5.3 5.5 6.9 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 CDJ69799.1 - 6.2 5.0 9.6 8.3 4.5 9.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1645 PF07816.11 CDJ69801.1 - 0.068 13.8 0.2 0.068 13.8 0.2 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1645) Presenilin PF01080.17 CDJ69801.1 - 0.74 8.5 28.9 0.035 12.9 21.2 2.3 2 0 0 2 2 2 0 Presenilin Otopetrin PF03189.13 CDJ69801.1 - 2.7 6.7 5.5 21 3.8 5.5 2.3 1 1 0 1 1 1 0 Otopetrin CobN-Mg_chel PF02514.16 CDJ69801.1 - 4.2 5.0 18.1 6.2 4.4 18.1 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase ALMT PF11744.8 CDJ69801.1 - 6 5.6 19.5 15 4.3 19.5 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter FbpA PF05833.11 CDJ69802.1 - 0.00022 20.1 36.2 0.00022 20.1 36.2 4.5 3 2 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) Choline_kinase PF01633.20 CDJ69803.1 - 1.9e-21 76.6 0.0 1e-16 61.2 0.0 2.3 2 0 0 2 2 2 2 Choline/ethanolamine kinase SUIM_assoc PF16619.5 CDJ69803.1 - 0.00074 19.5 23.4 0.0052 16.8 4.4 3.1 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ69803.1 - 0.023 14.3 21.1 0.088 12.4 5.7 2.2 2 0 0 2 2 2 0 Spt20 family GRP PF07172.11 CDJ69803.1 - 0.034 14.8 2.4 0.034 14.8 2.4 1.8 2 0 0 2 2 2 0 Glycine rich protein family DUF2722 PF10846.8 CDJ69803.1 - 0.32 9.9 14.3 0.54 9.1 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF1645 PF07816.11 CDJ69803.1 - 0.87 10.1 11.5 0.28 11.7 7.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ69803.1 - 2 8.0 9.9 5.2 6.6 9.9 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_11 PF13414.6 CDJ69804.1 - 5.5e-06 26.0 0.4 0.00031 20.3 0.1 3.0 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 CDJ69804.1 - 6.6e-06 25.9 2.1 0.00021 21.2 0.8 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ69804.1 - 1.9e-05 24.4 4.0 0.0002 21.2 0.8 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ69804.1 - 2.8e-05 23.7 0.7 2.8e-05 23.7 0.7 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ69804.1 - 3.1e-05 24.5 0.5 3.1e-05 24.5 0.5 4.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ69804.1 - 0.00033 20.8 0.4 0.068 13.6 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CDJ69804.1 - 0.0051 17.1 0.1 0.0051 17.1 0.1 4.5 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ69804.1 - 0.0067 16.6 0.0 0.0067 16.6 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ69804.1 - 0.16 12.0 2.6 3.1 8.0 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Spt20 PF12090.8 CDJ69804.1 - 0.39 10.3 11.3 1 8.9 11.3 1.6 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ69805.1 - 0.0053 17.1 16.7 0.0053 17.1 16.7 2.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Exonuc_VII_L PF02601.15 CDJ69805.1 - 0.42 10.1 10.0 0.56 9.7 10.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spt20 PF12090.8 CDJ69805.1 - 0.6 9.7 15.2 0.84 9.2 15.2 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ69805.1 - 1.8 8.5 24.9 2.3 8.1 24.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ69806.1 - 0.0083 16.2 0.9 0.0083 16.2 0.9 3.8 3 1 1 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ69806.1 - 0.011 15.7 26.3 0.18 11.8 17.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ69806.1 - 0.36 11.1 0.0 0.36 11.1 0.0 4.0 2 2 1 3 3 3 0 Anti-sigma-K factor rskA DUF2207 PF09972.9 CDJ69806.1 - 5.1 5.8 5.4 3.8 6.2 0.0 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) TTL PF03133.15 CDJ69807.1 - 2.2e-46 158.3 0.0 2.2e-46 158.3 0.0 2.2 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family Adaptin_binding PF10199.9 CDJ69807.1 - 3.5e-06 27.6 0.1 0.027 15.1 0.0 3.7 4 1 0 4 4 4 1 Alpha and gamma adaptin binding protein p34 ATPgrasp_ST PF14397.6 CDJ69807.1 - 9.8e-06 25.0 0.0 0.036 13.3 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 CDJ69807.1 - 5.4e-05 22.6 0.0 5.4e-05 22.6 0.0 4.1 3 1 1 4 4 4 2 YheC/D like ATP-grasp zf-C4H2 PF10146.9 CDJ69807.1 - 0.00025 21.4 3.7 0.00025 21.4 3.7 3.3 4 1 0 4 4 4 1 Zinc finger-containing protein RimK PF08443.11 CDJ69807.1 - 0.031 13.9 0.0 0.62 9.6 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain rRNA_processing PF08524.11 CDJ69807.1 - 0.54 10.3 22.0 0.98 9.4 0.0 3.8 3 0 0 3 3 3 0 rRNA processing AAA_23 PF13476.6 CDJ69807.1 - 9.3 6.7 9.3 1.5e+02 2.8 8.7 2.6 2 1 0 2 2 2 0 AAA domain Pyr_redox_2 PF07992.14 CDJ69809.1 - 7.6e-26 91.0 0.0 7.1e-13 48.4 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ69809.1 - 1.6e-10 41.3 0.0 3.2e-07 30.8 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF3446 PF11928.8 CDJ69809.1 - 0.0068 16.7 1.6 0.0068 16.7 1.6 2.5 2 0 0 2 2 2 1 Early growth response N-terminal domain KCNQ2_u3 PF16642.5 CDJ69809.1 - 0.0069 17.3 4.2 0.08 13.9 0.8 2.7 2 0 0 2 2 2 1 Unstructured region on Potassium channel subunit alpha KvLQT2 NAD_binding_7 PF13241.6 CDJ69809.1 - 0.0088 16.5 0.0 0.22 12.0 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Sporozoite_P67 PF05642.11 CDJ69809.1 - 0.13 10.3 0.0 0.2 9.7 0.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NAD_binding_8 PF13450.6 CDJ69809.1 - 1.3 9.4 3.4 21 5.4 0.0 3.3 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain MMS1_N PF10433.9 CDJ69810.1 - 4.9e-08 32.0 0.0 7.1e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term SR-25 PF10500.9 CDJ69811.1 - 2.9e-08 33.6 10.6 2.9e-08 33.6 10.6 4.5 2 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.11 CDJ69811.1 - 3.1 6.2 34.0 0.6 8.5 6.4 2.2 2 0 0 2 2 2 0 Peptidase family S64 SLC12 PF03522.15 CDJ69811.1 - 3.5 6.5 18.6 1.3 8.0 1.1 2.2 2 0 0 2 2 2 0 Solute carrier family 12 NPR3 PF03666.13 CDJ69811.1 - 4.1 6.1 29.7 0.5 9.1 5.5 2.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 PAN_4 PF14295.6 CDJ69812.1 - 2.4e-05 24.1 0.6 5.1e-05 23.1 0.6 1.5 1 0 0 1 1 1 1 PAN domain TTRAP PF14203.6 CDJ69813.1 - 0.16 12.0 2.3 3.7 7.6 0.3 2.5 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Exonuc_VII_L PF02601.15 CDJ69813.1 - 0.2 11.2 19.0 0.26 10.8 19.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.13 CDJ69813.1 - 0.82 9.6 22.3 1.3 9.0 22.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PMC2NT PF08066.12 CDJ69813.1 - 2.5 8.9 6.1 0.72 10.6 1.0 2.4 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF2228 PF10228.9 CDJ69813.1 - 3.5 7.3 13.3 1.9 8.2 0.8 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2228) PspA_IM30 PF04012.12 CDJ69813.1 - 4.4 6.8 35.3 0.088 12.4 11.1 2.1 1 1 1 2 2 2 0 PspA/IM30 family SR-25 PF10500.9 CDJ69814.1 - 2.6e-08 33.8 5.0 3.5e-08 33.4 5.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ69814.1 - 0.00018 21.9 4.6 0.00022 21.6 4.6 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ69814.1 - 0.002 17.8 11.0 0.0023 17.6 11.0 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ69814.1 - 0.0038 17.3 10.1 0.0038 17.3 10.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TCP PF03634.13 CDJ69814.1 - 0.013 16.1 4.6 0.019 15.5 4.6 1.3 1 0 0 1 1 1 0 TCP family transcription factor TMEM171 PF15471.6 CDJ69814.1 - 0.021 13.8 4.1 0.032 13.2 4.1 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 CCSAP PF15748.5 CDJ69814.1 - 0.026 14.7 7.7 0.034 14.3 7.7 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF900 PF05990.12 CDJ69814.1 - 0.039 13.5 0.1 0.05 13.1 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF4636 PF15468.6 CDJ69814.1 - 0.046 13.4 4.0 0.067 12.9 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF4614 PF15391.6 CDJ69814.1 - 0.066 13.2 10.3 0.083 12.9 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 CDJ69814.1 - 0.097 11.5 5.1 0.1 11.5 5.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Otopetrin PF03189.13 CDJ69814.1 - 0.12 11.2 0.8 0.15 10.8 0.8 1.0 1 0 0 1 1 1 0 Otopetrin Ndc1_Nup PF09531.10 CDJ69814.1 - 0.18 10.5 7.2 0.19 10.4 7.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 CDJ69814.1 - 0.31 11.0 5.4 0.33 10.9 5.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM199X PF15814.5 CDJ69814.1 - 0.56 9.2 9.2 0.66 9.0 9.2 1.1 1 0 0 1 1 1 0 Protein family FAM199X CbiD PF01888.17 CDJ69814.1 - 0.58 9.4 0.0 0.58 9.4 0.0 2.0 2 0 0 2 2 2 0 CbiD Presenilin PF01080.17 CDJ69814.1 - 0.6 8.8 5.3 0.76 8.5 5.3 1.1 1 0 0 1 1 1 0 Presenilin DUF508 PF04370.12 CDJ69814.1 - 0.98 9.2 8.1 1.3 8.7 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Corona_nucleoca PF00937.18 CDJ69814.1 - 2.6 7.0 13.4 3.2 6.7 13.4 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CDK2AP PF09806.9 CDJ69814.1 - 2.8 8.0 13.5 0.038 14.1 6.1 1.7 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein IMUP PF15761.5 CDJ69814.1 - 5.5 7.7 18.0 9 7.0 18.0 1.5 1 1 0 1 1 1 0 Immortalisation up-regulated protein LysM PF01476.20 CDJ69815.1 - 1.2e-08 34.8 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 LysM domain M_domain PF12938.7 CDJ69815.1 - 0.091 12.5 0.3 0.23 11.3 0.3 1.6 1 0 0 1 1 1 0 M domain of GW182 PepSY_2 PF13670.6 CDJ69815.1 - 1.2 9.2 5.6 2.6 8.1 5.6 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain RRM_1 PF00076.22 CDJ69816.1 - 1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5341 PF17276.2 CDJ69816.1 - 0.097 12.8 1.2 0.14 12.3 1.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5341) Spt20 PF12090.8 CDJ69816.1 - 0.14 11.8 15.1 0.21 11.2 15.1 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ69816.1 - 0.16 12.0 12.0 0.17 11.9 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5349 PF17298.2 CDJ69816.1 - 0.64 9.7 9.8 0.83 9.4 9.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF2722 PF10846.8 CDJ69816.1 - 1.2 8.0 12.3 1.5 7.7 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Androgen_recep PF02166.16 CDJ69816.1 - 8.1 5.2 14.7 12 4.6 14.7 1.3 1 0 0 1 1 1 0 Androgen receptor DEAD PF00270.29 CDJ69817.1 - 2.3e-18 66.6 0.4 2.3e-18 66.6 0.4 3.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ69817.1 - 2.7e-14 53.4 2.8 3e-14 53.3 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Cwf_Cwc_15 PF04889.12 CDJ69817.1 - 0.00026 20.8 5.5 0.00026 20.8 5.5 7.1 6 1 0 6 6 6 1 Cwf15/Cwc15 cell cycle control protein DUF755 PF05501.11 CDJ69817.1 - 0.0065 16.7 11.9 0.0065 16.7 11.9 11.6 7 4 4 11 11 11 1 Domain of unknown function (DUF755) FAD_binding_2 PF00890.24 CDJ69818.1 - 5.4e-71 239.9 4.3 7.5e-49 166.9 0.1 2.1 1 1 1 2 2 2 2 FAD binding domain Thi4 PF01946.17 CDJ69818.1 - 0.00092 18.5 0.7 0.15 11.3 0.1 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 CDJ69818.1 - 0.0083 15.4 0.4 0.016 14.4 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDJ69818.1 - 0.037 13.1 2.0 0.056 12.5 2.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 CDJ69818.1 - 0.18 10.5 0.6 0.28 9.9 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF3552 PF12072.8 CDJ69821.1 - 0.053 12.9 0.4 0.079 12.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) RT_RNaseH PF17917.1 CDJ69822.1 - 2.2e-26 92.2 0.0 2.8e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ69822.1 - 3.3e-23 81.6 0.0 5e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase VPS13_C PF16909.5 CDJ69823.1 - 1.9e-07 31.0 0.8 6.2e-07 29.4 0.8 1.8 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Ripply PF14998.6 CDJ69823.1 - 0.11 13.2 0.2 0.11 13.2 0.2 4.4 4 0 0 4 4 4 0 Transcription Regulator Spt20 PF12090.8 CDJ69823.1 - 0.48 10.0 56.6 0.32 10.6 3.9 4.3 4 0 0 4 4 4 0 Spt20 family TFIIA PF03153.13 CDJ69824.1 - 6.8 6.6 35.4 3.3 7.6 0.1 2.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ69825.1 - 0.11 12.5 0.0 0.11 12.5 0.0 20.4 19 2 0 19 19 19 0 Unstructured region C-term to UIM in Ataxin3 DUF4667 PF15700.5 CDJ69826.1 - 0.0038 17.4 3.5 0.0038 17.4 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ69826.1 - 0.021 14.5 14.0 0.026 14.1 14.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NSP2-B_epitope PF14757.6 CDJ69826.1 - 0.27 10.9 12.2 0.31 10.7 12.2 1.0 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein DUF755 PF05501.11 CDJ69826.1 - 1 9.6 13.5 1.3 9.3 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) PAP1 PF08601.10 CDJ69826.1 - 4.3 6.9 12.7 6.3 6.4 12.7 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 CCDC106 PF15794.5 CDJ69826.1 - 5.7 6.6 6.6 7.3 6.2 6.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CBM53 PF16760.5 CDJ69827.1 - 0.00015 22.3 0.0 0.00035 21.1 0.0 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Spt20 PF12090.8 CDJ69827.1 - 0.0013 18.4 8.1 0.0021 17.7 8.1 1.4 1 0 0 1 1 1 1 Spt20 family SUIM_assoc PF16619.5 CDJ69827.1 - 0.0089 16.1 8.4 0.0089 16.1 8.4 2.6 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ69827.1 - 0.02 14.9 8.8 0.026 14.5 8.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ69827.1 - 0.026 14.1 13.3 0.026 14.1 13.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1645 PF07816.11 CDJ69827.1 - 0.046 14.3 11.1 0.065 13.8 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF4667 PF15700.5 CDJ69827.1 - 0.58 10.2 14.4 0.065 13.3 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Presenilin PF01080.17 CDJ69827.1 - 2 7.1 4.2 2.6 6.7 4.2 1.2 1 0 0 1 1 1 0 Presenilin Herpes_pp85 PF04637.12 CDJ69827.1 - 3.8 5.8 6.0 5.4 5.3 6.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) ArfGap PF01412.18 CDJ69828.1 - 1.8e-20 73.2 2.1 1.5e-13 50.9 0.6 3.1 4 1 0 4 4 4 2 Putative GTPase activating protein for Arf DUF2722 PF10846.8 CDJ69828.1 - 0.0029 16.6 38.8 0.034 13.1 0.4 4.2 4 0 0 4 4 4 3 Protein of unknown function (DUF2722) NINJA_B PF16136.5 CDJ69828.1 - 0.0092 16.4 4.1 0.0092 16.4 4.1 5.2 5 0 0 5 5 5 2 Putative nuclear localisation signal ANAPC_CDC26 PF10471.9 CDJ69828.1 - 1 10.3 54.7 0.34 11.8 4.6 5.2 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit CDC26 SUIM_assoc PF16619.5 CDJ69828.1 - 3.7 7.7 71.5 2.9 8.0 10.4 4.9 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Collagen PF01391.18 CDJ69829.1 - 0.14 11.9 12.2 0.38 10.5 12.2 1.7 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Clat_adaptor_s PF01217.20 CDJ69830.1 - 1.9e-44 151.0 0.9 3e-42 143.9 0.9 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Cas_St_Csn2 PF16813.5 CDJ69830.1 - 0.047 12.8 0.1 0.086 11.9 0.0 1.4 1 1 1 2 2 2 0 CRISPR-associated protein Csn2 subfamily St DUF2722 PF10846.8 CDJ69831.1 - 2.6e-05 23.4 10.6 3.9e-05 22.8 0.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) PPR_3 PF13812.6 CDJ69831.1 - 0.00069 19.6 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 CDJ69831.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 PPR repeat family Spt20 PF12090.8 CDJ69831.1 - 0.076 12.6 29.6 0.099 12.2 15.9 2.1 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ69831.1 - 0.27 11.2 34.1 0.65 9.9 8.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 CDJ69831.1 - 0.56 9.8 7.8 1 8.9 7.8 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis eIF_4EBP PF05456.11 CDJ69831.1 - 0.91 9.5 8.0 0.063 13.2 2.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF2722 PF10846.8 CDJ69832.1 - 0.00034 19.7 26.7 0.0058 15.6 7.2 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ69832.1 - 0.00052 20.1 52.8 0.052 13.5 27.4 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit GCV_H PF01597.19 CDJ69832.1 - 0.0039 17.1 0.0 0.0095 15.8 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein RskA PF10099.9 CDJ69832.1 - 0.0058 16.9 23.0 0.0058 16.9 23.0 5.3 1 1 2 4 4 4 1 Anti-sigma-K factor rskA DUF3371 PF11851.8 CDJ69832.1 - 4.3 8.4 20.8 19 6.4 7.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Spt20 PF12090.8 CDJ69833.1 - 2.7 7.6 23.3 2.2 7.8 13.7 2.2 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 CDJ69833.1 - 4.5 8.3 4.9 7.2 7.6 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Med15 PF09606.10 CDJ69834.1 - 0.0002 20.3 14.7 0.00022 20.1 14.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ69834.1 - 0.00091 18.9 16.3 0.0013 18.4 16.3 1.2 1 0 0 1 1 1 1 Spt20 family dsDNA_bind PF01984.20 CDJ69834.1 - 0.0011 19.2 6.7 0.0011 19.2 6.7 2.1 2 0 0 2 2 2 1 Double-stranded DNA-binding domain RskA PF10099.9 CDJ69834.1 - 0.013 15.9 7.5 0.017 15.5 7.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Roughex PF06020.11 CDJ69834.1 - 0.028 13.5 4.8 0.037 13.1 4.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ69834.1 - 0.033 14.2 20.4 0.042 13.9 20.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PH_BEACH PF14844.6 CDJ69834.1 - 0.043 13.9 2.1 0.079 13.1 2.1 1.4 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Suf PF05843.14 CDJ69834.1 - 0.25 11.3 11.2 0.28 11.1 11.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 CDJ69834.1 - 0.81 7.9 15.0 0.99 7.6 15.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3128 PF11326.8 CDJ69834.1 - 3 8.3 10.6 0.29 11.5 5.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) DUF4834 PF16118.5 CDJ69834.1 - 4.4 8.3 8.0 7.9 7.5 8.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ69834.1 - 4.7 5.9 10.1 6 5.5 10.1 1.1 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ69834.1 - 5.2 4.0 12.5 5.8 3.9 12.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDK2AP PF09806.9 CDJ69835.1 - 3.6 7.6 6.3 5.4 7.0 6.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Mucin-like PF16058.5 CDJ69835.1 - 4.6 7.4 12.6 0.066 13.3 2.7 2.5 1 1 1 2 2 2 0 Mucin-like DSPn PF14671.6 CDJ69836.1 - 1.5e-18 67.6 0.1 3.3e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Methyltrans_SAM PF10672.9 CDJ69836.1 - 6.9e-10 38.5 0.0 2.8e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 S-adenosylmethionine-dependent methyltransferase DSPc PF00782.20 CDJ69836.1 - 1e-08 35.1 0.4 5.2e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain MTS PF05175.14 CDJ69836.1 - 1.3e-08 34.6 0.3 5.4e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 CDJ69836.1 - 3.5e-05 24.4 0.3 0.0018 18.9 0.1 2.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 CDJ69836.1 - 0.0004 20.3 0.0 0.0008 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF2722 PF10846.8 CDJ69836.1 - 0.00062 18.8 3.4 0.00097 18.2 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Methyltransf_31 PF13847.6 CDJ69836.1 - 0.00072 19.4 2.8 0.0011 18.8 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 CDJ69836.1 - 0.00073 19.0 0.1 0.00073 19.0 0.1 1.5 2 0 0 2 2 1 1 Ribosomal protein L11 methyltransferase (PrmA) PUA_3 PF17785.1 CDJ69836.1 - 0.0009 19.0 0.0 0.0035 17.1 0.0 2.0 1 1 0 1 1 1 1 PUA-like domain Y_phosphatase PF00102.27 CDJ69836.1 - 0.0022 17.6 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDJ69836.1 - 0.0081 16.3 0.9 0.014 15.5 0.0 1.8 2 0 0 2 2 1 1 Inositol hexakisphosphate Methyltransf_11 PF08241.12 CDJ69836.1 - 0.026 15.2 2.3 0.21 12.2 0.1 3.1 2 1 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ69836.1 - 0.063 12.9 9.8 0.18 11.5 0.3 2.6 2 1 1 3 3 2 0 Conserved hypothetical protein 95 TFIIA PF03153.13 CDJ69836.1 - 0.37 10.7 13.3 0.017 15.2 7.2 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ69836.1 - 1.1 10.2 3.2 2.3 9.2 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ69836.1 - 1.7 8.2 18.8 2.9 7.4 18.8 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ69836.1 - 5 7.0 6.3 8.5 6.3 6.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pkinase PF00069.25 CDJ69837.1 - 1.1e-32 113.5 0.0 1.6e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ69837.1 - 2e-22 79.7 0.0 3.3e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ69837.1 - 0.0048 16.9 1.6 0.0052 16.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Exo_endo_phos PF03372.23 CDJ69838.1 - 0.00018 21.1 0.0 0.0013 18.3 0.0 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Transcrip_act PF04949.13 CDJ69839.1 - 0.14 12.0 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Transcriptional activator IMPDH PF00478.25 CDJ69841.1 - 2.1e-125 418.3 1.0 3.7e-125 417.5 1.0 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CDJ69841.1 - 8.2e-11 42.2 0.1 0.00082 19.8 0.0 2.7 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CDJ69841.1 - 1.4e-10 40.8 2.7 3.3e-10 39.5 1.3 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CDJ69841.1 - 4.1e-10 39.6 7.3 2.3e-06 27.2 6.6 3.0 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 CDJ69841.1 - 1e-05 25.1 2.8 7.3e-05 22.3 2.8 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 CDJ69841.1 - 0.0015 17.9 2.8 0.0023 17.3 1.9 1.7 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 CDJ69841.1 - 0.0021 17.3 1.6 0.1 11.8 1.6 2.8 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase G3P_antiterm PF04309.12 CDJ69841.1 - 0.018 14.4 0.8 0.49 9.8 0.1 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DHO_dh PF01180.21 CDJ69841.1 - 0.041 13.1 1.3 0.12 11.5 1.3 1.8 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 CDJ69841.1 - 0.043 13.1 2.5 0.41 10.0 2.3 2.4 2 1 0 2 2 2 0 Thiamine monophosphate synthase NAD_binding_7 PF13241.6 CDJ69841.1 - 0.24 11.8 1.1 23 5.5 0.1 2.6 1 1 1 2 2 2 0 Putative NAD(P)-binding CTP_transf_like PF01467.26 CDJ69842.1 - 0.0086 16.3 0.4 0.19 11.9 0.0 3.0 3 1 0 3 3 3 1 Cytidylyltransferase-like FAD_syn PF06574.12 CDJ69842.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase NTP_transf_3 PF12804.7 CDJ69843.1 - 1.6e-13 51.3 0.0 3.5e-13 50.2 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 CDJ69843.1 - 1.6e-12 47.5 0.0 2.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CDJ69843.1 - 0.00051 19.7 0.4 0.15 11.8 0.1 2.9 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 CDJ69843.1 - 0.00096 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 L-fucokinase CTP_transf_3 PF02348.19 CDJ69843.1 - 0.11 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase DUF4954 PF16314.5 CDJ69843.1 - 0.14 10.2 0.1 0.2 9.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CpeT PF06206.11 CDJ69844.1 - 0.0027 17.7 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 CpeT/CpcT family (DUF1001) TPR_2 PF07719.17 CDJ69845.1 - 0.3 11.3 2.0 39 4.7 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DSPc PF00782.20 CDJ69846.1 - 4.5e-07 29.7 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Spt20 PF12090.8 CDJ69846.1 - 0.00021 21.0 15.4 0.00021 21.0 15.4 7.1 5 3 0 5 5 5 2 Spt20 family Y_phosphatase3 PF13350.6 CDJ69846.1 - 0.002 18.1 0.1 0.002 18.1 0.1 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family Glyco_transf_49 PF13896.6 CDJ69846.1 - 4 6.7 7.5 0.083 12.2 0.2 1.8 2 0 0 2 2 2 0 Glycosyl-transferase for dystroglycan Arm PF00514.23 CDJ69847.1 - 6.5e-12 45.1 0.0 0.00047 20.1 0.0 4.3 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CDJ69847.1 - 0.0003 20.3 0.4 0.011 15.3 0.0 2.8 3 0 0 3 3 3 1 Atypical Arm repeat Atx10homo_assoc PF09759.9 CDJ69847.1 - 0.099 12.7 0.0 10 6.2 0.0 2.9 1 1 2 3 3 3 0 Spinocerebellar ataxia type 10 protein domain DUF2722 PF10846.8 CDJ69848.1 - 0.00015 20.9 10.5 0.00016 20.8 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) SAGA-Tad1 PF12767.7 CDJ69848.1 - 0.007 16.1 4.1 0.0074 16.0 4.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Spt20 PF12090.8 CDJ69848.1 - 0.028 14.0 22.4 0.035 13.7 22.4 1.1 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 CDJ69848.1 - 0.45 8.7 16.7 0.47 8.7 16.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MMR1 PF08505.10 CDJ69848.1 - 0.65 10.2 12.0 0.81 9.9 12.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TERB2 PF15101.6 CDJ69848.1 - 0.9 9.6 15.4 1.2 9.1 15.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SpoIIP PF07454.11 CDJ69848.1 - 1.7 8.0 11.2 2.1 7.7 11.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Mitofilin PF09731.9 CDJ69848.1 - 2.1 7.1 25.6 2.6 6.8 25.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PCM1_C PF15717.5 CDJ69848.1 - 2.3 6.8 14.1 2.6 6.7 14.1 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus SOG2 PF10428.9 CDJ69848.1 - 3.2 6.8 13.0 3.9 6.6 13.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Sec62 PF03839.16 CDJ69848.1 - 3.7 7.0 9.9 4.8 6.6 9.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Neur_chan_memb PF02932.16 CDJ69848.1 - 5.3 7.0 10.1 6.3 6.8 10.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Miga PF10265.9 CDJ69848.1 - 5.6 5.8 8.9 7.3 5.4 8.9 1.1 1 0 0 1 1 1 0 Mitoguardin Presenilin PF01080.17 CDJ69848.1 - 5.9 5.6 15.1 6.7 5.4 15.1 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ69848.1 - 6.7 5.6 10.9 8 5.4 10.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CDJ69848.1 - 7.4 3.5 12.8 7.9 3.5 12.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CDJ69848.1 - 8.5 5.7 8.0 10 5.4 8.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4834 PF16118.5 CDJ69848.1 - 9.1 7.3 14.1 15 6.6 14.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RNase_P_p30 PF01876.16 CDJ69849.1 - 2.2e-18 66.5 1.9 1.4e-16 60.6 1.3 3.1 3 1 0 3 3 3 1 RNase P subunit p30 SUIM_assoc PF16619.5 CDJ69849.1 - 0.00087 19.3 18.3 0.15 12.2 1.4 3.5 3 0 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 Roughex PF06020.11 CDJ69850.1 - 0.0075 15.4 0.9 0.0084 15.3 0.9 1.1 1 0 0 1 1 1 1 Drosophila roughex protein SUIM_assoc PF16619.5 CDJ69850.1 - 0.012 15.6 4.0 0.017 15.2 4.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ69850.1 - 0.16 11.6 5.7 0.17 11.5 5.7 1.1 1 0 0 1 1 1 0 Spt20 family UQ_con PF00179.26 CDJ69851.1 - 4.2e-13 49.2 0.1 4.2e-13 49.2 0.1 2.9 3 1 0 3 3 3 1 Ubiquitin-conjugating enzyme RskA PF10099.9 CDJ69851.1 - 0.0094 16.3 0.2 0.0094 16.3 0.2 4.0 2 2 2 4 4 4 3 Anti-sigma-K factor rskA DUF572 PF04502.13 CDJ69851.1 - 1 8.9 47.0 5.7 6.5 41.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) MEKHLA PF08670.11 CDJ69853.1 - 0.021 14.7 0.3 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 MEKHLA domain DUF382 PF04037.13 CDJ69855.1 - 0.088 13.0 0.3 2 8.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF382) UPF0524 PF15823.5 CDJ69856.1 - 0.18 11.2 4.1 0.18 11.2 4.1 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 Band_3_cyto PF07565.13 CDJ69856.1 - 0.68 9.7 10.8 0.85 9.4 10.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex14_N PF04695.13 CDJ69856.1 - 0.89 10.2 23.8 1.1 9.9 23.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Herpes_UL25 PF01499.16 CDJ69856.1 - 0.92 8.0 11.1 0.94 7.9 11.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Phage_GPO PF05929.11 CDJ69856.1 - 3.9 7.0 17.2 4.3 6.9 17.2 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Roughex PF06020.11 CDJ69856.1 - 4.5 6.3 13.9 4.8 6.2 13.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ69856.1 - 7.1 6.5 35.1 8.3 6.3 35.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Jnk-SapK_ap_N PF09744.9 CDJ69856.1 - 7.6 6.7 19.7 9.6 6.4 19.7 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Cdh1_DBD_1 PF18196.1 CDJ69856.1 - 7.9 6.8 9.2 10 6.4 9.2 1.3 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 V_ATPase_I PF01496.19 CDJ69856.1 - 8.7 4.1 15.7 9.5 4.0 15.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AF-4 PF05110.13 CDJ69857.1 - 0.014 13.6 48.6 0.016 13.3 48.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TFIIA PF03153.13 CDJ69857.1 - 0.3 11.1 73.2 0.4 10.6 73.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 CDJ69857.1 - 8.7 4.5 11.4 11 4.2 11.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PrgH PF09480.10 CDJ69858.1 - 0.32 10.3 13.9 0.49 9.6 13.9 1.2 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Dapper PF15268.6 CDJ69858.1 - 0.55 9.0 38.6 0.67 8.7 38.6 1.0 1 0 0 1 1 1 0 Dapper TetR_C_1 PF02909.17 CDJ69858.1 - 2.4 8.0 20.6 0.44 10.4 8.5 3.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MCM PF00493.23 CDJ69859.1 - 9.3e-23 80.5 0.0 3.8e-22 78.5 0.0 1.9 1 1 0 1 1 1 1 MCM P-loop domain Ribosomal_L37 PF08561.10 CDJ69859.1 - 0.045 14.3 1.0 0.066 13.7 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Sgf11_N PF18519.1 CDJ69859.1 - 0.59 9.7 0.0 0.59 9.7 0.0 2.7 4 0 0 4 4 4 0 SAGA-associated factor 11 N-terminal domain Med3 PF11593.8 CDJ69859.1 - 5.8 6.0 12.0 1.1 8.4 2.4 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal SR-25 PF10500.9 CDJ69860.1 - 0.00041 20.0 12.7 0.00041 20.0 12.7 2.7 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Exonuc_VII_L PF02601.15 CDJ69860.1 - 0.015 14.9 21.6 0.015 14.8 21.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dicty_REP PF05086.12 CDJ69860.1 - 0.24 9.3 13.1 0.22 9.5 13.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SLC12 PF03522.15 CDJ69860.1 - 0.52 9.3 30.4 0.82 8.6 30.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 V_ATPase_I PF01496.19 CDJ69860.1 - 0.76 7.6 25.2 1.1 7.1 25.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RAP1 PF07218.11 CDJ69860.1 - 0.8 7.9 7.5 1.2 7.3 7.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CRT10 PF08728.10 CDJ69860.1 - 1.4 7.0 10.2 1.2 7.2 10.2 1.1 1 0 0 1 1 1 0 CRT10 CDK5_activator PF03261.15 CDJ69860.1 - 5.2 6.5 27.8 8.7 5.8 27.8 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Metallophos PF00149.28 CDJ69861.1 - 1e-31 111.1 0.0 1.4e-31 110.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ69861.1 - 0.046 13.9 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Transketolase_C PF02780.20 CDJ69862.1 - 6e-17 61.7 0.9 1.4e-14 54.0 0.1 3.1 3 0 0 3 3 3 1 Transketolase, C-terminal domain AAA_16 PF13191.6 CDJ69862.1 - 0.0065 16.9 12.2 0.0065 16.9 12.2 4.8 3 2 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 CDJ69862.1 - 0.012 15.5 0.0 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2722 PF10846.8 CDJ69862.1 - 0.013 14.5 6.4 0.023 13.7 4.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) AAA_22 PF13401.6 CDJ69862.1 - 0.13 12.6 0.0 0.13 12.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 CDJ69862.1 - 1.5 9.3 6.8 67 3.9 6.8 2.4 2 0 0 2 2 2 0 AAA domain Med15 PF09606.10 CDJ69862.1 - 3.5 6.2 25.5 0.4 9.3 16.5 2.6 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Utp21 PF04192.12 CDJ69863.1 - 3.6e-15 56.1 0.3 3.6e-15 56.1 0.3 4.3 4 1 0 4 4 4 1 Utp21 specific WD40 associated putative domain SR-25 PF10500.9 CDJ69863.1 - 5.7e-05 22.8 16.9 5.7e-05 22.8 16.9 3.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ69863.1 - 0.00084 19.7 0.0 0.00084 19.7 0.0 5.8 3 2 1 5 5 5 2 Anti-sigma-K factor rskA Rrn6 PF10214.9 CDJ69863.1 - 0.0044 15.6 0.4 0.0044 15.6 0.4 2.3 2 0 0 2 2 2 1 RNA polymerase I-specific transcription-initiation factor Velvet PF11754.8 CDJ69863.1 - 0.0058 16.6 0.2 0.0058 16.6 0.2 2.3 2 0 0 2 2 2 1 Velvet factor CobT PF06213.12 CDJ69863.1 - 0.03 13.7 0.1 0.03 13.7 0.1 3.3 3 1 0 3 3 3 0 Cobalamin biosynthesis protein CobT stn_TNFRSF12A PF12191.8 CDJ69863.1 - 0.035 14.3 0.1 0.035 14.3 0.1 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SPX PF03105.19 CDJ69863.1 - 0.58 10.0 21.9 1.2 9.0 22.0 1.7 1 1 0 1 1 1 0 SPX domain Otopetrin PF03189.13 CDJ69863.1 - 0.6 8.9 7.5 2 7.1 4.1 2.2 2 0 0 2 2 2 0 Otopetrin TFIIA PF03153.13 CDJ69863.1 - 0.99 9.3 65.5 0.17 11.8 6.3 3.0 3 1 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit PHD PF00628.29 CDJ69864.1 - 3.5e-12 46.0 7.9 3.5e-12 46.0 7.9 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 CDJ69864.1 - 2.3e-11 43.0 3.5 2.3e-11 43.0 3.5 2.2 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 CDJ69864.1 - 0.0005 20.0 4.9 0.0005 20.0 4.9 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_2 PF03107.16 CDJ69864.1 - 0.0046 17.3 0.9 0.0046 17.3 0.9 2.5 2 1 0 2 2 2 1 C1 domain C1_1 PF00130.22 CDJ69864.1 - 0.028 14.3 1.1 0.028 14.3 1.1 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CDC24_OB3 PF17244.2 CDJ69864.1 - 0.08 12.6 10.2 0.13 12.0 10.2 1.4 1 1 0 1 1 1 0 Cell division control protein 24, OB domain 3 zf-UDP PF14569.6 CDJ69864.1 - 0.12 12.5 8.9 0.036 14.2 5.8 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger MKT1_N PF12247.8 CDJ69864.1 - 0.21 11.9 0.6 4 7.9 0.1 2.2 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication zf-PHD-like PF15446.6 CDJ69864.1 - 0.31 10.6 13.5 0.11 12.1 9.6 2.3 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-B_box PF00643.24 CDJ69864.1 - 8.8 6.6 9.9 16 5.8 0.7 2.9 2 1 0 2 2 2 0 B-box zinc finger Activator_LAG-3 PF11498.8 CDJ69865.1 - 0.033 13.2 1.2 0.044 12.8 1.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Cpn60_TCP1 PF00118.24 CDJ69866.1 - 1.6e-68 231.6 0.0 1.8e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2722 PF10846.8 CDJ69867.1 - 4.3e-06 26.0 0.0 4.3e-06 26.0 0.0 10.7 10 2 1 11 11 11 6 Protein of unknown function (DUF2722) DUF4667 PF15700.5 CDJ69867.1 - 0.005 17.0 1.9 0.005 17.0 1.9 7.7 7 2 0 7 7 7 4 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ69867.1 - 0.0053 16.4 9.7 0.0053 16.4 9.7 10.1 9 2 0 9 9 9 4 Spt20 family MCU PF04678.13 CDJ69867.1 - 0.019 15.0 0.6 0.019 15.0 0.6 8.3 8 1 2 10 10 10 0 Mitochondrial calcium uniporter WES_acyltransf PF03007.16 CDJ69867.1 - 0.025 14.4 0.1 0.025 14.4 0.1 8.7 8 3 3 11 11 11 0 Wax ester synthase-like Acyl-CoA acyltransferase domain VCBS PF13517.6 CDJ69868.1 - 7.7e-20 71.2 0.3 6.3e-06 26.7 0.4 7.1 5 1 1 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CDJ69868.1 - 8.5e-10 38.6 18.2 1.9e-05 24.7 0.2 6.5 6 0 0 6 6 6 3 FG-GAP repeat MAGE_N PF12440.8 CDJ69868.1 - 0.0064 17.1 17.5 0.0064 17.1 17.5 11.0 6 3 4 10 10 4 1 Melanoma associated antigen family N terminal PAP1 PF08601.10 CDJ69868.1 - 0.0066 16.2 24.2 0.0066 16.2 24.2 4.6 2 2 0 4 4 3 1 Transcription factor PAP1 SUIM_assoc PF16619.5 CDJ69868.1 - 0.0098 15.9 0.1 0.0098 15.9 0.1 8.9 7 1 0 7 7 6 1 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 CDJ69868.1 - 0.093 13.1 0.2 0.093 13.1 0.2 5.6 4 1 0 4 4 3 0 Enhancer of polycomb-like DUF4083 PF13314.6 CDJ69868.1 - 0.14 12.2 0.2 0.39 10.7 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Itfg2 PF15907.5 CDJ69868.1 - 0.15 11.0 4.0 0.43 9.6 1.2 2.8 3 0 0 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 DUF5523 PF17661.1 CDJ69868.1 - 0.27 10.9 11.8 1.2 8.8 1.7 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5523) EphA2_TM PF14575.6 CDJ69868.1 - 1 10.3 0.0 1 10.3 0.0 4.8 4 1 0 4 4 3 0 Ephrin type-A receptor 2 transmembrane domain AAA_23 PF13476.6 CDJ69868.1 - 4.8 7.6 17.1 0.74 10.3 0.6 3.2 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 CDJ69869.1 - 1.8e-11 43.9 0.0 1.9e-05 24.2 0.0 3.9 3 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ69869.1 - 1.2e-05 24.7 0.0 0.033 13.5 0.0 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 CDJ69870.1 - 1.2e-10 41.5 12.3 6.2e-06 26.5 1.0 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ69870.1 - 4.5e-07 29.5 12.1 2.5e-05 23.9 3.4 3.5 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 CDJ69870.1 - 3.5e-06 26.6 0.9 4.8e-05 22.9 0.5 2.2 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 CDJ69870.1 - 0.0048 16.8 7.1 2.3 8.5 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeat Lin-8 PF03353.15 CDJ69870.1 - 0.015 14.9 3.2 0.023 14.3 3.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2722 PF10846.8 CDJ69870.1 - 0.66 8.9 13.8 0.27 10.2 9.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) HJURP_C PF12347.8 CDJ69870.1 - 1.2 9.3 5.5 3.8 7.6 5.5 1.9 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat GET2 PF08690.10 CDJ69870.1 - 1.6 8.4 7.9 8.8 5.9 5.4 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 LRR_1 PF00560.33 CDJ69870.1 - 5.6 7.9 19.0 16 6.5 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat DUF155 PF02582.14 CDJ69871.1 - 6.4e-14 52.4 0.1 6.4e-14 52.4 0.1 1.8 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Spt20 PF12090.8 CDJ69872.1 - 0.00081 19.1 31.2 0.013 15.1 5.4 3.1 3 0 0 3 3 3 2 Spt20 family SUIM_assoc PF16619.5 CDJ69872.1 - 0.003 17.6 1.8 0.003 17.6 1.8 4.1 4 1 0 4 4 2 1 Unstructured region C-term to UIM in Ataxin3 DUF4207 PF13904.6 CDJ69872.1 - 0.004 16.9 2.5 0.004 16.9 2.5 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4207) DUF2722 PF10846.8 CDJ69872.1 - 0.0071 15.3 2.2 0.0071 15.3 2.2 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF2722) SPX PF03105.19 CDJ69872.1 - 0.044 13.7 5.2 0.1 12.5 2.4 2.0 2 0 0 2 2 2 0 SPX domain Lin-8 PF03353.15 CDJ69872.1 - 0.065 12.8 10.6 0.072 12.6 2.4 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CAF1 PF04857.20 CDJ69872.1 - 0.072 12.2 0.0 3.2 6.8 0.0 2.1 2 0 0 2 2 2 0 CAF1 family ribonuclease RskA PF10099.9 CDJ69872.1 - 0.44 10.8 52.8 1.9 8.7 15.3 3.3 1 1 2 3 3 3 0 Anti-sigma-K factor rskA DUF4064 PF13273.6 CDJ69872.1 - 0.67 10.3 1.7 22 5.4 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF3464 PF11947.8 CDJ69872.1 - 0.69 9.7 5.2 5 6.9 0.0 3.1 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 Med15 PF09606.10 CDJ69872.1 - 2.8 6.5 38.6 1.4 7.5 11.4 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1980 PF09323.10 CDJ69872.1 - 4.6 7.1 4.7 17 5.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Shadoo PF14999.6 CDJ69872.1 - 5.5 7.1 10.2 14 5.8 5.2 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective TFIIA PF03153.13 CDJ69872.1 - 6.7 6.6 42.8 1.7 8.6 11.9 2.2 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit SMYLE_N PF18615.1 CDJ69873.1 - 0.89 9.0 22.8 1.3 8.5 22.8 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF4667 PF15700.5 CDJ69874.1 - 0.0093 16.1 5.7 0.65 10.0 0.7 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) DUF3947 PF13135.6 CDJ69874.1 - 0.019 15.2 3.3 0.035 14.3 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) DUF4769 PF15992.5 CDJ69874.1 - 0.16 11.8 0.3 10 5.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4769) IMUP PF15761.5 CDJ69874.1 - 1.9 9.2 27.6 7.2 7.3 9.2 2.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein TFIIA PF03153.13 CDJ69874.1 - 4.6 7.1 7.7 10 6.0 2.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ69875.1 - 5.3 7.2 116.3 0.23 11.5 7.0 7.6 7 0 0 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 DUF3824 PF12868.7 CDJ69876.1 - 0.00048 20.8 9.1 0.00061 20.5 9.1 1.1 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) TRAP_alpha PF03896.16 CDJ69876.1 - 0.0024 17.1 5.0 0.0029 16.9 5.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit CD20 PF04103.15 CDJ69876.1 - 0.0025 17.9 0.6 0.0027 17.8 0.6 1.1 1 0 0 1 1 1 1 CD20-like family DUF4820 PF16091.5 CDJ69876.1 - 0.0034 16.8 8.8 0.0043 16.5 8.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) DUF5327 PF17261.2 CDJ69876.1 - 0.0062 17.2 15.3 0.0075 17.0 15.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5327) Presenilin PF01080.17 CDJ69876.1 - 0.0073 15.1 16.1 0.0077 15.1 16.1 1.0 1 0 0 1 1 1 1 Presenilin FHIPEP PF00771.20 CDJ69876.1 - 0.0073 14.8 7.6 0.0083 14.6 7.6 1.0 1 0 0 1 1 1 1 FHIPEP family Connexin PF00029.19 CDJ69876.1 - 0.0074 16.1 7.7 0.0074 16.1 7.7 1.1 1 0 0 1 1 1 1 Connexin FAM176 PF14851.6 CDJ69876.1 - 0.0093 15.6 4.1 0.0099 15.5 4.1 1.1 1 0 0 1 1 1 1 FAM176 family SpoIIP PF07454.11 CDJ69876.1 - 0.011 15.2 12.8 0.011 15.2 12.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CobT PF06213.12 CDJ69876.1 - 0.014 14.8 18.7 0.014 14.8 18.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT V_ATPase_I PF01496.19 CDJ69876.1 - 0.015 13.3 11.9 0.015 13.3 11.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AIF_C PF14721.6 CDJ69876.1 - 0.027 14.8 11.0 0.032 14.6 11.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SID-1_RNA_chan PF13965.6 CDJ69876.1 - 0.032 12.7 4.1 0.036 12.5 4.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FmiP_Thoc5 PF09766.9 CDJ69876.1 - 0.033 13.5 16.1 0.034 13.4 16.1 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 G0-G1_switch_2 PF15103.6 CDJ69876.1 - 0.039 14.4 8.7 0.039 14.4 8.7 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF1980 PF09323.10 CDJ69876.1 - 0.04 13.8 10.4 0.047 13.6 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CLN3 PF02487.17 CDJ69876.1 - 0.042 12.9 9.0 0.052 12.6 9.0 1.0 1 0 0 1 1 1 0 CLN3 protein PigN PF04987.14 CDJ69876.1 - 0.052 12.4 4.9 0.059 12.2 4.9 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF4628 PF15429.6 CDJ69876.1 - 0.053 13.2 10.2 0.064 12.9 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Pex26 PF07163.12 CDJ69876.1 - 0.053 12.8 14.9 0.059 12.7 14.9 1.0 1 0 0 1 1 1 0 Pex26 protein DcuA_DcuB PF03605.14 CDJ69876.1 - 0.062 12.2 4.3 0.068 12.1 4.3 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF4228 PF14009.6 CDJ69876.1 - 0.073 13.5 10.3 0.08 13.3 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) CPSF100_C PF13299.6 CDJ69876.1 - 0.077 13.2 11.8 0.084 13.1 11.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal HA2 PF04408.23 CDJ69876.1 - 0.08 13.2 7.7 0.098 12.9 7.7 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) PPL5 PF18168.1 CDJ69876.1 - 0.081 12.2 8.9 0.092 12.0 8.9 1.0 1 0 0 1 1 1 0 Prim-pol family 5 DUF2828 PF11443.8 CDJ69876.1 - 0.095 10.8 11.9 0.094 10.8 11.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) YibE_F PF07907.11 CDJ69876.1 - 0.098 12.1 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 YibE/F-like protein CSG2 PF16965.5 CDJ69876.1 - 0.1 11.5 6.2 0.12 11.3 6.2 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator PIP5K PF01504.18 CDJ69876.1 - 0.1 11.8 9.4 0.098 11.9 9.4 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Ureide_permease PF07168.11 CDJ69876.1 - 0.11 11.3 6.5 0.11 11.2 6.5 1.0 1 0 0 1 1 1 0 Ureide permease PAP2_3 PF14378.6 CDJ69876.1 - 0.11 12.1 0.2 0.12 12.0 0.2 1.0 1 0 0 1 1 1 0 PAP2 superfamily CBP_BcsG PF11658.8 CDJ69876.1 - 0.12 10.8 10.9 0.12 10.7 10.9 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Baculo_PP31 PF05311.11 CDJ69876.1 - 0.14 11.7 11.6 0.13 11.7 11.6 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) O-antigen_lig PF13425.6 CDJ69876.1 - 0.16 10.8 2.5 0.17 10.6 2.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CCDC53 PF10152.9 CDJ69876.1 - 0.17 12.3 15.3 0.19 12.2 15.3 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Serinc PF03348.15 CDJ69876.1 - 0.17 10.8 9.1 0.19 10.6 9.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) SLC12 PF03522.15 CDJ69876.1 - 0.17 10.8 12.1 0.17 10.9 12.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF3408 PF11888.8 CDJ69876.1 - 0.21 11.7 14.9 0.23 11.6 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) 2HCT PF03390.15 CDJ69876.1 - 0.21 10.2 3.3 0.25 9.9 3.3 1.0 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family CbiD PF01888.17 CDJ69876.1 - 0.24 10.7 7.9 0.26 10.5 7.9 1.0 1 0 0 1 1 1 0 CbiD Pex14_N PF04695.13 CDJ69876.1 - 0.24 12.0 25.5 0.27 11.9 25.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF913 PF06025.12 CDJ69876.1 - 0.26 10.2 8.9 0.25 10.3 8.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3450 PF11932.8 CDJ69876.1 - 0.26 10.6 27.6 0.3 10.4 27.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TFIIA PF03153.13 CDJ69876.1 - 0.26 11.2 40.8 0.27 11.2 40.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ69876.1 - 0.27 11.4 14.6 0.27 11.4 14.6 1.0 1 0 0 1 1 1 0 DDHD domain EOS1 PF12326.8 CDJ69876.1 - 0.28 11.1 8.1 0.31 11.0 8.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein OATP PF03137.20 CDJ69876.1 - 0.28 9.4 6.4 0.3 9.3 6.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Scs3p PF10261.9 CDJ69876.1 - 0.3 10.6 4.4 0.37 10.3 4.4 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Pannexin_like PF12534.8 CDJ69876.1 - 0.31 10.1 9.7 0.31 10.1 9.7 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 MTABC_N PF16185.5 CDJ69876.1 - 0.31 10.5 3.1 0.39 10.2 3.1 1.3 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region Gastrin PF00918.17 CDJ69876.1 - 0.35 11.8 14.1 0.42 11.6 14.1 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF3381 PF11861.8 CDJ69876.1 - 0.36 10.6 15.3 0.4 10.5 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Peroxin-13_N PF04088.13 CDJ69876.1 - 0.36 11.1 7.2 0.43 10.9 7.2 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Band_3_cyto PF07565.13 CDJ69876.1 - 0.38 10.5 12.3 0.41 10.4 12.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Velvet PF11754.8 CDJ69876.1 - 0.39 10.6 13.4 0.37 10.7 13.4 1.0 1 0 0 1 1 1 0 Velvet factor Folate_carrier PF01770.18 CDJ69876.1 - 0.4 9.3 7.1 0.43 9.3 7.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier R_equi_Vir PF05526.11 CDJ69876.1 - 0.42 10.5 9.7 0.45 10.4 9.7 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Ctr PF04145.15 CDJ69876.1 - 0.44 11.1 7.7 0.53 10.9 7.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family ABC2_membrane_2 PF12679.7 CDJ69876.1 - 0.46 9.7 8.3 0.62 9.3 8.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein PepSY_TM PF03929.16 CDJ69876.1 - 0.58 9.8 9.0 0.7 9.5 9.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region BAF1_ABF1 PF04684.13 CDJ69876.1 - 0.64 9.0 17.2 0.7 8.9 17.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDC45 PF02724.14 CDJ69876.1 - 0.64 8.3 12.2 0.69 8.1 12.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 CDJ69876.1 - 0.69 9.9 9.7 0.71 9.9 9.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region VIT1 PF01988.19 CDJ69876.1 - 0.79 9.5 6.5 1 9.2 6.5 1.2 1 0 0 1 1 1 0 VIT family TERB2 PF15101.6 CDJ69876.1 - 0.8 9.7 22.3 0.83 9.7 22.3 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 YABBY PF04690.13 CDJ69876.1 - 0.82 10.2 10.6 0.91 10.1 10.6 1.1 1 0 0 1 1 1 0 YABBY protein Zip PF02535.22 CDJ69876.1 - 0.87 8.7 4.5 0.96 8.6 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Dpy19 PF10034.9 CDJ69876.1 - 0.89 7.7 4.6 1 7.5 4.6 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation NEMP PF10225.9 CDJ69876.1 - 0.9 9.1 6.0 1 9.0 6.0 1.0 1 0 0 1 1 1 0 NEMP family DUF2227 PF09988.9 CDJ69876.1 - 0.96 9.3 2.1 1.2 9.0 2.1 1.3 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) eIF-3_zeta PF05091.12 CDJ69876.1 - 0.97 8.3 22.0 0.95 8.4 22.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIIBC-GUT_N PF03612.14 CDJ69876.1 - 1.1 8.9 14.7 1.3 8.7 14.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FYDLN_acid PF09538.10 CDJ69876.1 - 1.1 9.9 9.8 1.7 9.4 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Folliculin PF11704.8 CDJ69876.1 - 1.2 9.0 14.2 1.2 9.0 14.2 1.0 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport ALMT PF11744.8 CDJ69876.1 - 1.2 7.9 11.1 1.1 8.0 11.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Coilin_N PF15862.5 CDJ69876.1 - 1.2 9.0 19.5 1.6 8.5 19.5 1.3 1 0 0 1 1 1 0 Coilin N-terminus Gti1_Pac2 PF09729.9 CDJ69876.1 - 1.5 8.9 12.2 1.4 8.9 12.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Rxt3 PF08642.10 CDJ69876.1 - 1.5 9.6 8.1 1.9 9.3 8.1 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 AAA_23 PF13476.6 CDJ69876.1 - 1.7 9.1 17.1 1.7 9.1 17.1 1.1 1 0 0 1 1 1 0 AAA domain Endonuc_Holl PF10107.9 CDJ69876.1 - 1.9 8.3 9.8 1.8 8.4 9.8 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase THOC2_N PF16134.5 CDJ69876.1 - 2 6.9 14.5 2.3 6.7 14.5 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF4175 PF13779.6 CDJ69876.1 - 2.1 6.2 34.1 2 6.2 34.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Trp_oprn_chp PF09534.10 CDJ69876.1 - 2.2 8.1 10.9 2.8 7.7 10.9 1.3 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CTU2 PF10288.9 CDJ69876.1 - 2.4 8.4 15.7 3.7 7.8 15.7 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 EPL1 PF10513.9 CDJ69876.1 - 2.8 8.3 17.5 2.9 8.3 17.5 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like API5 PF05918.11 CDJ69876.1 - 2.9 6.6 17.3 2.9 6.6 17.3 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MCU PF04678.13 CDJ69876.1 - 2.9 7.9 11.5 2.9 7.9 11.5 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter FAM60A PF15396.6 CDJ69876.1 - 3.1 7.7 13.1 3.6 7.6 13.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ69876.1 - 3.1 7.5 17.8 3.4 7.4 17.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HemX PF04375.14 CDJ69876.1 - 3.2 7.0 32.5 3.4 6.9 32.5 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase PAT1 PF09770.9 CDJ69876.1 - 3.2 5.9 26.9 3.2 5.9 26.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RskA PF10099.9 CDJ69876.1 - 3.4 7.9 29.8 7.2 6.9 29.8 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF702 PF05142.12 CDJ69876.1 - 3.4 8.1 17.0 4 7.9 17.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF1180 PF06679.12 CDJ69876.1 - 3.4 8.0 10.6 3.8 7.9 10.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) UPF0239 PF06783.11 CDJ69876.1 - 3.9 7.7 11.2 5.1 7.3 11.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) TFB6 PF17110.5 CDJ69876.1 - 3.9 7.2 10.4 4.6 7.0 10.4 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2232 PF09991.9 CDJ69876.1 - 4.3 6.4 7.9 4.9 6.3 7.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) HCO3_cotransp PF00955.21 CDJ69876.1 - 4.4 6.0 5.2 4.6 6.0 5.2 1.1 1 0 0 1 1 1 0 HCO3- transporter family Peptidase_U57 PF05582.12 CDJ69876.1 - 5.1 6.3 11.8 5.2 6.2 11.8 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Ndc1_Nup PF09531.10 CDJ69876.1 - 5.3 5.6 14.4 5.3 5.6 14.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MMR1 PF08505.10 CDJ69876.1 - 5.4 7.2 20.4 5.4 7.2 20.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FliP PF00813.20 CDJ69876.1 - 5.7 6.8 6.1 6.3 6.6 6.1 1.1 1 0 0 1 1 1 0 FliP family DUF2126 PF09899.9 CDJ69876.1 - 5.8 4.9 13.5 6.6 4.7 13.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Tim54 PF11711.8 CDJ69876.1 - 5.8 5.6 17.9 6.4 5.5 17.9 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Kei1 PF08552.11 CDJ69876.1 - 6.1 6.7 14.2 6.8 6.5 14.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 LEA_3 PF03242.13 CDJ69876.1 - 6.4 7.6 13.9 21 5.9 13.9 1.8 1 1 0 1 1 1 0 Late embryogenesis abundant protein Cellulose_synt PF03552.14 CDJ69876.1 - 6.6 5.1 6.2 6.5 5.1 6.2 1.0 1 0 0 1 1 1 0 Cellulose synthase Spt20 PF12090.8 CDJ69876.1 - 7 6.2 49.5 9.4 5.8 49.5 1.2 1 0 0 1 1 1 0 Spt20 family ArAE_2_N PF10337.9 CDJ69876.1 - 7.4 5.5 11.9 8.6 5.3 11.9 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Paf1 PF03985.13 CDJ69876.1 - 7.4 5.4 21.3 7.9 5.4 21.3 1.0 1 0 0 1 1 1 0 Paf1 Membralin PF09746.9 CDJ69876.1 - 8 5.4 9.2 9.1 5.2 9.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein MRP-S27 PF10037.9 CDJ69876.1 - 9.2 5.0 19.6 9.4 5.0 19.6 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Ribosomal_60s PF00428.19 CDJ69876.1 - 10 6.8 15.0 12 6.5 15.0 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein SUIM_assoc PF16619.5 CDJ69878.1 - 2.6e-05 24.2 0.3 7.5e-05 22.7 0.3 1.9 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Cullin PF00888.22 CDJ69878.1 - 0.00029 19.6 0.1 0.0015 17.2 0.1 1.8 1 1 0 1 1 1 1 Cullin family DUF4838 PF16126.5 CDJ69878.1 - 0.034 13.5 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) DUF2722 PF10846.8 CDJ69878.1 - 0.065 12.2 3.9 0.09 11.7 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ69878.1 - 0.18 11.4 9.5 0.27 10.8 9.5 1.2 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ69878.1 - 0.55 9.4 10.0 0.84 8.8 10.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 CDJ69878.1 - 1.5 8.7 10.5 2 8.4 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TrbI PF03743.14 CDJ69878.1 - 9.4 6.0 7.2 7.2 6.4 4.4 1.9 1 1 1 2 2 2 0 Bacterial conjugation TrbI-like protein SUIM_assoc PF16619.5 CDJ69879.1 - 4.9e-05 23.3 93.1 0.028 14.5 11.0 8.6 9 0 0 9 9 9 6 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 CDJ69879.1 - 2.9 8.9 0.0 2.9 8.9 0.0 7.7 8 1 1 9 9 9 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ69880.1 - 0.00062 19.9 54.1 0.00062 19.9 54.1 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Hydrolase_3 PF08282.12 CDJ69880.1 - 9 6.0 6.7 2.5 7.8 2.3 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase LisH PF08513.11 CDJ69881.1 - 6.3e-07 29.1 0.2 1.3e-06 28.2 0.2 1.5 1 0 0 1 1 1 1 LisH SUIM_assoc PF16619.5 CDJ69881.1 - 0.001 19.1 3.4 0.001 19.1 3.4 3.2 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 THOC2_N PF16134.5 CDJ69881.1 - 0.014 14.1 0.1 0.018 13.7 0.1 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF2140 PF09911.9 CDJ69881.1 - 0.058 12.9 1.9 0.12 11.9 1.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF2890 PF11081.8 CDJ69881.1 - 0.12 12.5 7.2 1.9 8.6 4.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) DUF4820 PF16091.5 CDJ69881.1 - 0.12 11.7 1.8 0.13 11.6 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Pex14_N PF04695.13 CDJ69881.1 - 0.58 10.8 17.2 0.12 13.1 6.7 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC53 PF10152.9 CDJ69881.1 - 0.83 10.1 12.0 3.1 8.2 12.0 2.0 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex SR-25 PF10500.9 CDJ69881.1 - 1.3 8.5 32.2 0.13 11.9 12.2 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ69881.1 - 2.5 6.9 6.3 4.3 6.1 3.6 2.3 2 1 0 2 2 2 0 Golgi-body localisation protein domain Spore_IV_A PF09547.10 CDJ69883.1 - 0.027 13.4 1.6 0.04 12.8 1.6 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) SLAC1 PF03595.17 CDJ69883.1 - 0.23 10.7 1.3 10 5.3 0.5 2.2 2 0 0 2 2 2 0 Voltage-dependent anion channel Allexi_40kDa PF05549.11 CDJ69883.1 - 6.8 6.1 11.1 4.5 6.7 0.2 2.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein Methyltransf_23 PF13489.6 CDJ69885.1 - 0.02 14.7 0.1 4.1 7.2 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain Spt20 PF12090.8 CDJ69885.1 - 0.021 14.4 37.1 0.42 10.2 5.7 4.3 4 0 0 4 4 4 0 Spt20 family DDE_Tnp_IS66_C PF13817.6 CDJ69885.1 - 0.13 12.5 0.1 40 4.5 0.0 3.1 2 0 0 2 2 2 0 IS66 C-terminal element SR-25 PF10500.9 CDJ69885.1 - 3.5 7.2 29.7 0.037 13.6 1.0 3.6 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF1168 PF06658.12 CDJ69886.1 - 2.9e-12 46.6 9.0 9.5e-12 44.9 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) Pex14_N PF04695.13 CDJ69886.1 - 0.00039 21.1 10.5 0.00039 21.1 10.5 2.0 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ69886.1 - 0.00062 19.5 30.0 0.019 14.6 0.3 2.1 2 0 0 2 2 2 2 Spt20 family Lin-8 PF03353.15 CDJ69886.1 - 0.027 14.0 8.0 0.029 13.9 8.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SUIM_assoc PF16619.5 CDJ69886.1 - 0.028 14.5 5.8 0.028 14.5 5.8 3.9 2 1 0 2 2 1 0 Unstructured region C-term to UIM in Ataxin3 PAT1 PF09770.9 CDJ69886.1 - 0.52 8.5 19.8 0.65 8.2 19.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2722 PF10846.8 CDJ69886.1 - 0.56 9.1 23.9 0.2 10.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ69886.1 - 0.66 8.7 10.0 0.84 8.3 10.0 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ69886.1 - 0.68 8.6 7.6 0.85 8.2 7.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_60s PF00428.19 CDJ69886.1 - 0.91 10.2 15.6 0.3 11.7 11.3 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein WTX PF09422.10 CDJ69886.1 - 2.1 7.3 8.4 3.1 6.8 8.4 1.2 1 0 0 1 1 1 0 WTX protein NINJA_B PF16136.5 CDJ69886.1 - 3.9 7.9 10.4 14 6.1 10.4 1.9 1 1 0 1 1 1 0 Putative nuclear localisation signal CDK5_activator PF03261.15 CDJ69886.1 - 4.7 6.6 11.5 6.5 6.2 11.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein V_ATPase_I PF01496.19 CDJ69886.1 - 4.8 5.0 9.4 6 4.7 9.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MDM10 PF12519.8 CDJ69886.1 - 7.2 5.3 6.9 9 5.0 6.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 YEATS PF03366.16 CDJ69887.1 - 0.17 11.8 17.2 14 5.7 0.1 6.9 5 3 3 8 8 8 0 YEATS family Epimerase PF01370.21 CDJ69887.1 - 0.26 10.7 5.5 11 5.4 0.0 4.3 4 1 0 4 4 4 0 NAD dependent epimerase/dehydratase family Rib_5-P_isom_A PF06026.14 CDJ69887.1 - 0.85 9.2 4.5 0.61 9.7 0.7 2.7 3 0 0 3 3 3 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) CS PF04969.16 CDJ69888.1 - 2.6e-05 25.2 0.0 4.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 CS domain His_Phos_1 PF00300.22 CDJ69889.1 - 1e-20 74.2 0.1 2.8e-20 72.8 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1768 PF08719.11 CDJ69890.1 - 4.2e-12 46.6 0.0 9.2e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_1 PF00076.22 CDJ69890.1 - 7.5e-12 44.9 0.0 4.6e-11 42.4 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.26 CDJ69890.1 - 5.7e-10 39.4 0.0 1.6e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ69890.1 - 1e-06 29.0 0.0 2.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RRM_7 PF16367.5 CDJ69890.1 - 0.15 12.2 0.0 0.52 10.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif IMP2_N PF18590.1 CDJ69891.1 - 8.6e-20 71.1 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain Pex14_N PF04695.13 CDJ69891.1 - 0.85 10.3 9.8 0.49 11.0 7.4 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_L37 PF08561.10 CDJ69892.1 - 0.00047 20.7 3.1 0.0019 18.7 3.1 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 Apt1 PF10351.9 CDJ69893.1 - 0.19 10.5 3.3 0.32 9.8 3.3 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3446 PF11928.8 CDJ69893.1 - 1.4 9.3 40.3 1.5 9.2 14.1 3.2 3 0 0 3 3 3 0 Early growth response N-terminal domain SPX PF03105.19 CDJ69893.1 - 2.4 8.0 7.1 5.9 6.7 7.3 1.5 1 1 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ69895.1 - 0.012 14.5 11.8 0.015 14.2 11.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1822 PF08852.11 CDJ69895.1 - 0.042 12.9 1.2 0.063 12.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) TFIIA PF03153.13 CDJ69895.1 - 0.06 13.3 8.9 0.088 12.8 8.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ69895.1 - 0.13 10.8 14.4 0.18 10.4 14.4 1.2 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 CDJ69895.1 - 0.13 12.2 15.2 0.17 11.8 15.2 1.2 1 0 0 1 1 1 0 SPX domain Tox-MPTase2 PF15638.6 CDJ69895.1 - 0.16 11.7 0.3 0.26 11.0 0.3 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 SRP-alpha_N PF04086.13 CDJ69895.1 - 0.35 10.8 15.9 0.46 10.3 15.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF572 PF04502.13 CDJ69895.1 - 4.3 6.9 11.7 6 6.4 11.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) NAD_binding_11 PF14833.6 CDJ69896.1 - 5.3e-32 110.6 0.0 1.1e-31 109.7 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 CDJ69896.1 - 2.8e-17 63.3 0.0 3.2e-08 33.9 0.0 2.4 1 1 1 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CDJ69896.1 - 0.0041 17.7 0.0 0.0078 16.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ran_BP1 PF00638.18 CDJ69897.1 - 2.6e-30 105.2 5.2 3.2e-20 72.6 0.8 2.8 3 0 0 3 3 3 2 RanBP1 domain Glyco_trans_2_3 PF13632.6 CDJ69897.1 - 0.0056 16.6 1.2 0.0088 16.0 1.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Ecl1 PF12855.7 CDJ69898.1 - 0.43 11.7 15.4 0.69 11.1 15.4 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Dynein_C PF18199.1 CDJ69899.1 - 1.3e-66 224.9 0.0 1.9e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CDJ69899.1 - 2.7e-56 189.9 0.0 3.9e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ69899.1 - 2.1e-11 44.0 0.1 5.7e-11 42.6 0.1 1.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 CDJ69900.1 - 1.9e-37 128.5 0.0 3.2e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 CDJ69900.1 - 7.4e-21 74.6 0.1 1.5e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDJ69900.1 - 8.5e-07 29.0 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ69900.1 - 0.014 15.6 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain WSD PF15613.6 CDJ69900.1 - 0.053 14.0 0.1 0.37 11.3 0.1 2.3 2 1 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif AAA_6 PF12774.7 CDJ69901.1 - 2.3e-143 477.1 0.0 4e-143 476.3 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ69901.1 - 1.4e-82 277.9 5.5 1.4e-82 277.9 5.5 3.6 2 2 1 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 CDJ69901.1 - 7.7e-09 35.7 0.0 1e-05 25.5 0.0 4.1 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ69901.1 - 9.5e-06 26.1 0.0 0.49 10.7 0.0 3.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_7 PF12775.7 CDJ69901.1 - 2.4e-05 23.9 0.4 0.025 14.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 CDJ69901.1 - 0.00015 22.1 0.4 0.16 12.2 0.1 3.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ69901.1 - 0.00024 21.6 3.8 0.21 12.2 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 CDJ69901.1 - 0.00034 20.4 1.6 0.22 11.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CDJ69901.1 - 0.00075 19.9 2.6 0.11 12.9 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDJ69901.1 - 0.009 16.4 0.2 2.1 8.8 0.0 3.3 3 0 0 3 3 3 1 RNA helicase DUF853 PF05872.12 CDJ69901.1 - 0.0099 14.5 3.6 0.26 9.8 0.2 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) TniB PF05621.11 CDJ69901.1 - 0.016 14.7 0.0 0.052 12.9 0.0 1.9 1 0 0 1 1 1 0 Bacterial TniB protein TrwB_AAD_bind PF10412.9 CDJ69901.1 - 0.019 13.9 3.2 0.054 12.4 0.2 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 CDJ69901.1 - 0.024 14.0 0.8 0.47 9.8 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_28 PF13521.6 CDJ69901.1 - 0.042 14.1 5.1 2.9 8.1 0.1 3.5 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 CDJ69901.1 - 0.059 12.4 0.3 0.33 10.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 CDJ69901.1 - 0.094 12.6 0.1 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase SRP54 PF00448.22 CDJ69901.1 - 0.1 12.2 1.9 3.3 7.3 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 CDJ69901.1 - 0.11 12.4 1.0 15 5.4 0.0 4.0 4 0 0 4 4 3 0 NACHT domain AAA_19 PF13245.6 CDJ69901.1 - 0.13 12.6 5.4 15 5.9 0.2 3.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CDJ69901.1 - 0.18 11.9 0.9 19 5.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain BCL_N PF04714.13 CDJ69901.1 - 0.2 11.7 1.8 0.51 10.4 0.4 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region RHH_4 PF13467.6 CDJ69901.1 - 0.21 11.5 2.8 1.7 8.6 0.1 3.3 3 1 0 3 3 3 0 Ribbon-helix-helix domain PhoH PF02562.16 CDJ69901.1 - 0.26 10.7 1.9 3 7.3 0.1 2.7 2 0 0 2 2 2 0 PhoH-like protein DUF4510 PF14971.6 CDJ69901.1 - 0.47 10.8 2.8 5.1 7.4 0.3 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4510) DUF2205 PF10224.9 CDJ69901.1 - 0.61 10.1 8.8 0.6 10.1 0.6 4.5 5 0 0 5 5 4 0 Short coiled-coil protein KIF1B PF12423.8 CDJ69901.1 - 1 9.8 2.8 3.5 8.1 0.5 2.5 2 0 0 2 2 2 0 Kinesin protein 1B Arnt_C PF18583.1 CDJ69901.1 - 1.2 8.8 4.1 0.95 9.1 0.2 2.4 2 0 0 2 2 2 0 Aminoarabinose transferase C-terminal domain Seryl_tRNA_N PF02403.22 CDJ69901.1 - 1.3 9.3 9.9 2 8.7 1.0 4.3 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4047 PF13256.6 CDJ69902.1 - 0.1 12.8 0.2 0.16 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DHC_N1 PF08385.12 CDJ69903.1 - 3.4e-49 167.9 13.1 9.2e-41 140.1 6.7 2.1 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 WD40 PF00400.32 CDJ69904.1 - 9.5e-13 48.4 6.2 0.003 18.4 0.4 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat tRNA-synt_2b PF00587.25 CDJ69905.1 - 2.4e-20 73.3 0.0 5e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CDJ69905.1 - 1.1e-05 25.5 0.1 2.2e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain Uma2 PF05685.12 CDJ69905.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative restriction endonuclease AMP-binding PF00501.28 CDJ69906.1 - 0.00055 18.6 0.0 0.001 17.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 CDJ69907.1 - 8.1e-14 51.0 0.0 1.4e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Profilin PF00235.19 CDJ69909.1 - 9.6e-13 48.5 0.0 1e-12 48.4 0.0 1.1 1 0 0 1 1 1 1 Profilin Hydrolase_4 PF12146.8 CDJ69912.1 - 2.5e-11 43.3 8.6 4.9e-09 35.8 0.6 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DUF2227 PF09988.9 CDJ69912.1 - 0.047 13.6 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) UPF0227 PF05728.12 CDJ69912.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2407 PF10302.9 CDJ69912.1 - 0.099 13.2 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Tmemb_cc2 PF10267.9 CDJ69912.1 - 5.7 6.0 6.6 13 4.8 6.6 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein ANAPC1 PF12859.7 CDJ69912.1 - 6 7.4 11.7 2.3 8.8 6.7 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 HD_2 PF12917.7 CDJ69913.1 - 0.013 15.2 2.7 0.02 14.7 2.7 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Ldt_C PF17969.1 CDJ69913.1 - 0.021 15.6 1.6 0.17 12.7 0.0 2.7 2 1 1 3 3 3 0 L,D-transpeptidase C-terminal domain V_ATPase_I PF01496.19 CDJ69913.1 - 0.43 8.5 2.4 0.54 8.1 2.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapD PF07072.11 CDJ69913.1 - 1.1 8.9 9.8 0.3 10.8 3.7 2.1 1 1 1 2 2 2 0 Cell division protein Peptidase_S46 PF10459.9 CDJ69914.1 - 3.2 6.3 21.2 4.4 5.8 21.2 1.1 1 0 0 1 1 1 0 Peptidase S46 CAC1F_C PF16885.5 CDJ69914.1 - 4.1 7.0 24.6 5.2 6.6 24.6 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term PIG-U PF06728.13 CDJ69915.1 - 0.13 11.3 2.3 11 4.9 0.0 3.3 2 1 1 3 3 3 0 GPI transamidase subunit PIG-U SR-25 PF10500.9 CDJ69916.1 - 1.1 8.9 11.2 1.4 8.5 11.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ69916.1 - 3.9 7.8 11.2 7.5 6.9 11.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) zf-rbx1 PF12678.7 CDJ69918.1 - 9.5e-06 25.8 4.2 1.5e-05 25.1 4.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CDJ69918.1 - 3.4e-05 23.8 1.5 4.7e-05 23.3 1.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger IMUP PF15761.5 CDJ69918.1 - 0.058 14.1 19.3 0.13 13.0 19.3 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF508 PF04370.12 CDJ69918.1 - 0.71 9.6 10.7 0.96 9.2 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) AF-4 PF05110.13 CDJ69918.1 - 3.9 5.4 22.1 4.4 5.3 22.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NAM-associated PF14303.6 CDJ69918.1 - 9.9 6.9 11.0 20 5.9 11.0 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain BSP_II PF05432.11 CDJ69919.1 - 0.16 11.6 9.9 0.25 11.0 9.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Med15 PF09606.10 CDJ69919.1 - 0.21 10.2 10.1 0.32 9.6 10.1 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ69919.1 - 1.4 8.4 13.7 2.6 7.6 13.7 1.4 1 0 0 1 1 1 0 Spt20 family MscS_TM PF12794.7 CDJ69919.1 - 4.2 6.1 4.9 6.9 5.4 4.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 TT_ORF2 PF02957.15 CDJ69919.1 - 5.2 8.0 9.4 1.8 9.5 5.8 2.0 2 0 0 2 2 2 0 TT viral ORF2 FAM176 PF14851.6 CDJ69919.1 - 6.2 6.5 11.3 1.1 8.9 6.4 2.1 2 0 0 2 2 2 0 FAM176 family Presenilin PF01080.17 CDJ69919.1 - 7.3 5.2 6.2 9.3 4.9 6.2 1.2 1 0 0 1 1 1 0 Presenilin BRF1 PF07741.13 CDJ69920.1 - 1.2 9.6 9.4 1.5 9.2 9.4 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Ctf8 PF09696.10 CDJ69920.1 - 2.7 8.3 19.8 3.3 8.1 19.8 1.1 1 0 0 1 1 1 0 Ctf8 F-protein PF00469.20 CDJ69920.1 - 2.9 7.4 11.7 3.2 7.3 11.7 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Baculo_PP31 PF05311.11 CDJ69920.1 - 8.9 5.7 10.7 9.7 5.6 10.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Spt20 PF12090.8 CDJ69922.1 - 0.13 11.9 15.9 0.31 10.6 3.0 2.7 2 0 0 2 2 2 0 Spt20 family CTNNBL PF08216.11 CDJ69922.1 - 0.63 10.2 3.5 1.4 9.1 0.5 2.7 2 1 1 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear PAN_4 PF14295.6 CDJ69924.1 - 6.6e-09 35.5 0.6 0.00028 20.7 0.1 2.6 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 CDJ69924.1 - 1.2e-06 28.4 7.8 0.0035 17.3 0.0 3.4 3 0 0 3 3 3 2 PAN domain DUF2207 PF09972.9 CDJ69925.1 - 0.12 11.1 0.4 0.16 10.7 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4079 PF13301.6 CDJ69925.1 - 0.73 10.0 6.5 0.047 13.8 1.8 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF2231 PF09990.9 CDJ69925.1 - 0.8 10.2 8.1 1.2 9.6 8.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) MS_channel PF00924.18 CDJ69926.1 - 3.7e-12 46.2 2.4 5.7e-12 45.6 2.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel PRP9_N PF16958.5 CDJ69926.1 - 0.12 12.4 0.3 21 5.1 0.1 2.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus TMEM234 PF10639.9 CDJ69927.1 - 5.1e-16 58.7 0.3 8.4e-16 58.0 0.3 1.3 1 0 0 1 1 1 1 Putative transmembrane family 234 DivIC PF04977.15 CDJ69927.1 - 0.0054 16.5 8.6 0.0054 16.5 8.6 1.5 2 0 0 2 2 2 1 Septum formation initiator DUF4834 PF16118.5 CDJ69927.1 - 0.0062 17.5 2.9 0.0062 17.5 2.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ69927.1 - 0.011 14.8 13.6 0.011 14.7 13.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF775 PF05603.12 CDJ69927.1 - 0.011 15.3 1.9 0.012 15.2 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) LMBR1 PF04791.16 CDJ69927.1 - 0.017 14.1 0.4 0.02 13.8 0.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF5336 PF17270.2 CDJ69927.1 - 0.019 14.6 5.3 0.026 14.2 5.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Suf PF05843.14 CDJ69927.1 - 0.032 14.2 4.1 0.034 14.1 4.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) OATP PF03137.20 CDJ69927.1 - 0.042 12.1 0.0 0.044 12.1 0.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Dpy19 PF10034.9 CDJ69927.1 - 0.06 11.6 0.2 0.062 11.5 0.2 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Orf78 PF06024.12 CDJ69927.1 - 0.063 13.6 0.1 0.081 13.2 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) DUF2417 PF10329.9 CDJ69927.1 - 0.068 12.6 0.4 0.083 12.3 0.4 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) EphA2_TM PF14575.6 CDJ69927.1 - 0.086 13.7 0.3 0.14 13.1 0.3 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TFIIA PF03153.13 CDJ69927.1 - 0.087 12.8 14.0 0.092 12.7 14.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1673 PF07895.11 CDJ69927.1 - 0.11 12.2 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Renin_r PF07850.14 CDJ69927.1 - 0.17 12.5 1.5 0.27 11.8 1.5 1.4 1 1 0 1 1 1 0 Renin receptor-like protein DUF3464 PF11947.8 CDJ69927.1 - 0.18 11.6 1.5 0.24 11.2 1.5 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4175 PF13779.6 CDJ69927.1 - 0.23 9.3 11.6 0.26 9.2 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF5421 PF17458.2 CDJ69927.1 - 0.39 10.1 9.4 0.48 9.8 9.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Med15 PF09606.10 CDJ69927.1 - 0.47 9.1 16.1 0.5 9.0 16.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ69927.1 - 1.2 8.6 25.3 1.5 8.4 25.3 1.1 1 0 0 1 1 1 0 Spt20 family dsDNA_bind PF01984.20 CDJ69927.1 - 2.3 8.5 18.8 3 8.1 18.8 1.1 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Activator_LAG-3 PF11498.8 CDJ69927.1 - 4.6 6.1 27.9 5.7 5.8 27.9 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Androgen_recep PF02166.16 CDJ69927.1 - 9.9 4.9 18.7 11 4.8 18.7 1.0 1 0 0 1 1 1 0 Androgen receptor tRNA_edit PF04073.15 CDJ69928.1 - 1.7e-05 24.9 1.5 0.0028 17.7 1.3 2.9 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Tic110 PF16940.5 CDJ69928.1 - 0.18 10.3 6.6 0.22 10.0 6.6 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Glyco_hydro_9 PF00759.19 CDJ69928.1 - 9.8 5.5 12.7 14 5.0 12.7 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Citrate_synt PF00285.21 CDJ69929.1 - 1.4e-57 195.4 0.1 3.1e-36 125.2 0.0 2.1 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain SIP1 PF04938.12 CDJ69930.1 - 0.00096 18.9 39.2 0.00096 18.9 39.2 3.2 2 2 1 3 3 3 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) SPX PF03105.19 CDJ69930.1 - 0.001 19.0 31.7 0.019 14.9 8.5 2.2 2 0 0 2 2 2 2 SPX domain SR-25 PF10500.9 CDJ69930.1 - 0.0026 17.4 4.6 0.0026 17.4 4.6 3.8 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein GET2 PF08690.10 CDJ69930.1 - 0.0091 15.7 14.8 0.0091 15.7 14.8 3.1 3 0 0 3 3 3 2 GET complex subunit GET2 DUF2550 PF10739.9 CDJ69930.1 - 0.56 10.2 3.5 2 8.5 3.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) DUF4207 PF13904.6 CDJ69930.1 - 4.8 6.8 58.9 1.8 8.2 12.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) His_Phos_1 PF00300.22 CDJ69931.1 - 1e-05 25.3 4.1 0.024 14.3 0.6 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) TFIIA PF03153.13 CDJ69931.1 - 0.0061 16.6 9.2 0.0069 16.4 9.2 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ69931.1 - 0.0097 15.5 9.5 0.0097 15.5 9.5 1.1 1 0 0 1 1 1 1 Spt20 family DUF305 PF03713.13 CDJ69931.1 - 0.018 15.2 8.3 0.021 15.0 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF305) DUF2722 PF10846.8 CDJ69931.1 - 0.023 13.6 6.0 0.023 13.6 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4407 PF14362.6 CDJ69931.1 - 0.2 11.0 8.1 0.25 10.6 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Activator_LAG-3 PF11498.8 CDJ69931.1 - 0.29 10.1 16.6 0.36 9.8 16.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3138 PF11336.8 CDJ69931.1 - 0.3 9.7 10.5 0.35 9.4 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DLIC PF05783.11 CDJ69931.1 - 0.39 9.5 2.6 0.44 9.3 2.6 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF5427 PF10310.9 CDJ69931.1 - 6.7 5.6 9.2 7.9 5.3 9.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Tho2 PF11262.8 CDJ69933.1 - 5.9e-60 203.0 3.6 1.9e-41 142.2 0.0 2.7 3 0 0 3 3 3 2 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 CDJ69933.1 - 3.2e-20 72.4 10.2 9.6e-12 44.3 0.0 4.5 4 0 0 4 4 4 2 THO complex subunit 2 N-terminus Leu_zip PF15294.6 CDJ69933.1 - 0.0031 17.1 4.0 0.0067 16.0 4.0 1.5 1 0 0 1 1 1 1 Leucine zipper ABC2_membrane PF01061.24 CDJ69935.1 - 9.5e-35 119.9 20.6 1.4e-34 119.4 20.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CDJ69935.1 - 1e-22 81.1 2.6 1.9e-20 73.8 0.1 3.2 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CDJ69935.1 - 6.6e-08 32.7 0.2 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CDJ69935.1 - 7.2e-06 26.5 0.0 2.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 CDJ69935.1 - 9.1e-05 21.7 17.0 9.1e-05 21.7 17.0 2.6 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_22 PF13401.6 CDJ69935.1 - 0.00019 21.7 0.2 0.0018 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CDJ69935.1 - 0.00023 21.1 0.4 0.00057 19.8 0.4 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CDJ69935.1 - 0.0011 18.7 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 CDJ69935.1 - 0.0011 18.1 0.1 0.0021 17.2 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 CDJ69935.1 - 0.0011 19.5 3.0 0.006 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CDJ69935.1 - 0.0064 16.0 0.1 0.98 8.8 0.1 2.5 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 CDJ69935.1 - 0.0065 16.1 0.2 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 CDJ69935.1 - 0.0095 16.4 0.0 0.029 14.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDJ69935.1 - 0.012 16.2 0.1 0.035 14.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 CDJ69935.1 - 0.013 15.7 0.1 0.013 15.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CDJ69935.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 CDJ69935.1 - 0.024 14.7 0.3 0.048 13.7 0.3 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 CDJ69935.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 CDJ69935.1 - 0.027 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 CDJ69935.1 - 0.034 14.1 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 CDJ69935.1 - 0.035 13.8 0.1 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CDJ69935.1 - 0.043 13.7 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 CDJ69935.1 - 0.049 13.3 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CDJ69935.1 - 0.05 13.8 1.2 0.06 13.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 CDJ69935.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CDJ69935.1 - 0.11 11.8 0.7 0.98 8.7 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Spt20 PF12090.8 CDJ69935.1 - 0.12 12.0 7.2 0.19 11.3 7.2 1.2 1 0 0 1 1 1 0 Spt20 family AAA_25 PF13481.6 CDJ69935.1 - 0.18 11.4 0.0 0.48 10.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CDJ69935.1 - 0.19 11.7 0.0 0.72 9.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CDJ69935.1 - 0.79 9.8 3.7 0.56 10.2 0.4 2.1 2 0 0 2 2 2 0 Dynamin family TRAPPC10 PF12584.8 CDJ69936.1 - 0.00029 20.5 0.0 0.0013 18.5 0.0 2.1 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 AUX_IAA PF02309.16 CDJ69936.1 - 4.3 7.1 0.0 4.3 7.1 0.0 3.2 3 1 0 3 3 3 0 AUX/IAA family Spt20 PF12090.8 CDJ69936.1 - 9.8 5.7 11.7 1.5 8.4 0.8 3.1 3 0 0 3 3 3 0 Spt20 family Pex19 PF04614.12 CDJ69937.1 - 0.061 13.1 0.5 0.058 13.2 0.5 1.1 1 0 0 1 1 1 0 Pex19 protein family Tma16 PF11176.8 CDJ69937.1 - 0.068 13.0 3.1 0.081 12.8 3.1 1.2 1 0 0 1 1 1 0 Translation machinery-associated protein 16 DUF241 PF03087.14 CDJ69937.1 - 0.19 11.5 5.4 0.22 11.3 5.4 1.0 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Ribosomal_L30_N PF08079.12 CDJ69937.1 - 0.78 10.0 21.2 1.5 9.1 20.3 1.8 1 1 0 1 1 1 0 Ribosomal L30 N-terminal domain TRM PF02005.16 CDJ69938.1 - 3.8e-90 302.8 0.0 3.1e-39 135.2 0.5 3.1 3 0 0 3 3 3 3 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 CDJ69938.1 - 0.087 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zf-IS66 PF13005.7 CDJ69938.1 - 1.9 8.9 4.1 11 6.5 0.3 2.7 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Tau95 PF09734.9 CDJ69940.1 - 4.3e-26 92.4 1.6 5.8e-23 82.3 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CDJ69940.1 - 0.048 13.9 4.7 0.89 9.7 0.0 3.4 2 2 1 3 3 3 0 Tau95 Triple barrel domain GDI PF00996.18 CDJ69941.1 - 4.3e-15 55.2 0.0 5e-07 28.6 0.0 3.4 4 0 0 4 4 4 3 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CDJ69941.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SprA-related PF12118.8 CDJ69942.1 - 0.026 13.7 19.4 0.033 13.3 19.4 1.1 1 0 0 1 1 1 0 SprA-related family ORC3_N PF07034.11 CDJ69942.1 - 0.36 9.9 10.2 0.44 9.6 10.2 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus TFIIA PF03153.13 CDJ69942.1 - 0.39 10.7 26.0 0.46 10.4 26.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATPase PF06745.13 CDJ69942.1 - 1.1 8.5 4.4 2.2 7.6 0.0 2.1 1 1 1 2 2 2 0 KaiC PAT1 PF09770.9 CDJ69942.1 - 1.4 7.1 21.4 1.5 7.0 21.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ69942.1 - 2.4 7.9 16.1 3.1 7.5 16.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PA26 PF04636.13 CDJ69942.1 - 3 6.7 12.5 3.9 6.3 12.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Mitoc_mL59 PF18126.1 CDJ69943.1 - 0.00019 21.7 3.9 0.006 16.9 3.9 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Ank_2 PF12796.7 CDJ69944.1 - 8e-15 55.2 5.6 1.4e-13 51.2 0.5 4.2 4 2 1 5 5 5 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ69944.1 - 7.9e-13 48.2 8.7 0.00029 21.2 0.4 6.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 CDJ69944.1 - 1.8e-12 46.3 6.5 0.00029 21.1 0.0 6.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 CDJ69944.1 - 1.4e-10 41.5 0.2 1.3e-05 25.7 0.0 4.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ69944.1 - 1.7e-09 37.7 3.0 0.00014 22.0 0.5 4.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) SET PF00856.28 CDJ69944.1 - 0.0025 18.2 0.1 0.0065 16.9 0.0 1.8 2 0 0 2 2 2 1 SET domain TPR_17 PF13431.6 CDJ69944.1 - 0.15 12.5 0.2 0.7 10.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.29 CDJ69946.1 - 2e-40 138.3 0.0 4.8e-40 137.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ69946.1 - 9.5e-12 44.5 0.1 2e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CDJ69946.1 - 2.7e-11 43.2 0.5 7.7e-11 41.8 0.5 1.9 1 1 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CDJ69946.1 - 3.2e-06 27.2 0.1 1.5e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ69946.1 - 4.8e-05 23.8 0.3 0.0056 17.1 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CDJ69946.1 - 0.00012 21.8 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDJ69946.1 - 0.00048 20.3 0.0 0.002 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ69946.1 - 0.00086 19.6 0.5 0.11 12.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CDJ69946.1 - 0.0018 18.4 0.0 0.0058 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDJ69946.1 - 0.0028 17.1 0.3 0.01 15.2 0.0 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CDJ69946.1 - 0.025 13.9 0.1 0.4 10.0 0.0 2.4 2 0 0 2 2 2 0 KaiC DUF815 PF05673.13 CDJ69946.1 - 0.044 12.9 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 CDJ69946.1 - 0.045 13.2 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 CDJ69946.1 - 0.055 13.9 0.1 1 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CDJ69946.1 - 0.055 13.4 0.4 2.8 7.8 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CDJ69946.1 - 0.061 12.6 0.5 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin ZapB PF06005.12 CDJ69946.1 - 0.061 13.8 1.3 0.23 11.9 0.4 2.4 2 0 0 2 2 2 0 Cell division protein ZapB AAA_24 PF13479.6 CDJ69946.1 - 0.068 12.9 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDJ69946.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein CPT PF07931.12 CDJ69946.1 - 0.089 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Gram_pos_anchor PF00746.21 CDJ69947.1 - 4.9 7.2 6.5 5.1 7.1 0.5 2.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Retrotrans_gag PF03732.17 CDJ69948.1 - 0.0087 16.3 0.0 0.041 14.2 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 CDJ69948.1 - 0.057 13.5 11.9 0.94 9.7 2.0 2.4 2 0 0 2 2 2 0 Zinc knuckle zinc-ribbons_6 PF07191.12 CDJ69948.1 - 0.095 12.7 1.7 0.18 11.8 1.7 1.3 1 0 0 1 1 1 0 zinc-ribbons DnaJ_CXXCXGXG PF00684.19 CDJ69948.1 - 0.53 10.7 8.3 1.4 9.3 8.3 1.7 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_6 PF15288.6 CDJ69948.1 - 0.67 9.8 8.8 0.42 10.5 0.6 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ69948.1 - 2.7 8.0 7.3 0.44 10.6 0.9 2.5 1 1 1 2 2 2 0 Zinc knuckle RVP_2 PF08284.11 CDJ69949.1 - 3.7e-10 39.7 0.0 6.1e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 CDJ69949.1 - 3.6e-09 36.5 0.0 6.4e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ69949.1 - 4.5e-08 33.6 0.0 9.3e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ69949.1 - 6.1e-08 33.1 0.0 1.6e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ69949.1 - 0.0024 17.6 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ69949.1 - 0.072 13.4 0.0 0.24 11.7 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.12 CDJ69949.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Spt20 PF12090.8 CDJ69950.1 - 3e-06 27.0 7.2 3e-06 27.0 7.2 2.5 2 1 0 2 2 2 1 Spt20 family vMSA PF00695.19 CDJ69951.1 - 0.023 13.8 0.5 0.025 13.7 0.5 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus SR-25 PF10500.9 CDJ69952.1 - 0.01 15.5 25.0 0.012 15.2 25.0 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1387 PF07139.11 CDJ69952.1 - 7 6.3 34.8 8.6 6.0 34.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CAML PF14963.6 CDJ69952.1 - 7.2 6.7 20.2 8.6 6.4 20.2 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand E1_dh PF00676.20 CDJ69954.1 - 8.6e-64 215.3 0.0 9.9e-64 215.1 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CDJ69954.1 - 0.099 11.8 0.1 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase AF-4 PF05110.13 CDJ69955.1 - 4 5.4 25.3 5.3 5.0 25.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LapA_dom PF06305.11 CDJ69956.1 - 0.0079 16.0 0.6 0.0079 16.0 0.6 3.8 5 0 0 5 5 5 1 Lipopolysaccharide assembly protein A domain DUF4692 PF15763.5 CDJ69956.1 - 0.012 16.0 7.3 0.012 16.0 7.3 3.8 3 1 1 4 4 4 0 Regulator of human erythroid cell expansion (RHEX) WBP-1 PF11669.8 CDJ69956.1 - 0.2 12.3 0.2 0.2 12.3 0.2 4.4 4 0 0 4 4 4 0 WW domain-binding protein 1 SR-25 PF10500.9 CDJ69956.1 - 0.62 9.6 51.1 0.1 12.2 25.5 2.8 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF572 PF04502.13 CDJ69956.1 - 0.71 9.4 21.9 0.039 13.6 13.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Hid1 PF12722.7 CDJ69956.1 - 0.79 7.8 16.8 0.52 8.4 12.2 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein PAP1 PF08601.10 CDJ69956.1 - 2.9 7.5 27.3 0.27 10.9 6.9 3.2 3 0 0 3 3 3 0 Transcription factor PAP1 Peptidase_S64 PF08192.11 CDJ69956.1 - 3.4 6.0 21.5 0.29 9.6 15.8 1.8 2 0 0 2 2 2 0 Peptidase family S64 RskA PF10099.9 CDJ69957.1 - 0.029 14.7 5.1 0.035 14.4 5.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Peroxin-3 PF04882.12 CDJ69957.1 - 0.045 12.7 2.4 0.055 12.5 2.4 1.0 1 0 0 1 1 1 0 Peroxin-3 Apt1 PF10351.9 CDJ69957.1 - 4.1 6.2 11.8 4.9 5.9 11.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HALZ PF02183.18 CDJ69960.1 - 0.00013 22.1 0.3 0.00013 22.1 0.3 7.4 6 2 2 8 8 8 2 Homeobox associated leucine zipper SUIM_assoc PF16619.5 CDJ69960.1 - 0.0024 17.9 1.3 0.0024 17.9 1.3 11.4 6 3 3 9 9 9 2 Unstructured region C-term to UIM in Ataxin3 PNP_UDP_1 PF01048.20 CDJ69961.1 - 1.2e-19 70.5 0.0 1.5e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily SR-25 PF10500.9 CDJ69964.1 - 1.2e-05 25.1 22.5 9.7e-05 22.1 13.5 2.8 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein PRIMA1 PF16101.5 CDJ69964.1 - 1.4 9.0 10.1 0.55 10.3 4.1 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SARAF PF06682.12 CDJ69964.1 - 6 6.4 24.6 0.21 11.2 11.9 2.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SPX PF03105.19 CDJ69965.1 - 0.0026 17.8 15.9 0.0038 17.2 15.9 1.3 1 0 0 1 1 1 1 SPX domain FAM176 PF14851.6 CDJ69965.1 - 0.037 13.7 14.9 0.2 11.3 0.8 2.2 2 0 0 2 2 2 0 FAM176 family Gti1_Pac2 PF09729.9 CDJ69965.1 - 1.6 8.8 20.6 1.8 8.6 8.7 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family EphA2_TM PF14575.6 CDJ69965.1 - 2.1 9.3 0.0 2.1 9.3 0.0 3.2 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain SpoIIP PF07454.11 CDJ69965.1 - 2.4 7.6 19.3 0.53 9.7 13.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Band_3_cyto PF07565.13 CDJ69965.1 - 2.8 7.7 17.1 0.43 10.4 8.7 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4834 PF16118.5 CDJ69965.1 - 9.3 7.3 27.0 8.7 7.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CNDH2_C PF16858.5 CDJ69966.1 - 4.6e-05 23.4 9.3 0.75 9.6 0.0 2.3 2 1 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Presenilin PF01080.17 CDJ69966.1 - 2.9 6.5 31.6 0.1 11.3 4.0 2.1 2 0 0 2 2 2 0 Presenilin WD40 PF00400.32 CDJ69968.1 - 3.6e-09 37.1 0.4 2.6e-05 24.9 0.1 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ69968.1 - 0.00028 21.1 0.0 0.048 14.0 0.0 3.0 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ69968.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Telomere_Sde2_2 PF13297.6 CDJ69969.1 - 1.7e-16 59.6 0.7 1.7e-16 59.6 0.7 1.8 2 0 0 2 2 2 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 CDJ69969.1 - 4.2e-13 49.4 0.2 4.2e-13 49.4 0.2 2.8 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Sec3_C PF09763.9 CDJ69970.1 - 0.41 9.0 0.4 0.48 8.7 0.4 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 SLBP_RNA_bind PF15247.6 CDJ69971.1 - 1.7e-23 82.5 1.3 4e-23 81.3 1.3 1.7 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain TFIIA PF03153.13 CDJ69971.1 - 0.69 9.9 10.3 1.1 9.1 10.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TBP PF00352.21 CDJ69973.1 - 3.3e-12 46.2 0.0 1.1e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) RNA_pol_Rpb2_6 PF00562.28 CDJ69974.1 - 9.2e-124 413.4 0.0 1.2e-123 413.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDJ69974.1 - 9.3e-60 201.6 0.0 1.3e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CDJ69974.1 - 7.1e-48 162.8 0.0 1.2e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CDJ69974.1 - 3.6e-33 113.8 0.5 8e-33 112.7 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 CDJ69974.1 - 3.4e-26 91.2 0.0 7.6e-26 90.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 CDJ69974.1 - 1.7e-20 73.0 0.1 3.4e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 CDJ69974.1 - 1.8e-16 60.5 1.8 4.8e-16 59.1 1.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNase_PH PF01138.21 CDJ69975.1 - 1.7e-15 57.7 3.2 7.1e-15 55.7 3.2 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 SCPU PF05229.15 CDJ69975.1 - 0.043 14.2 0.6 0.082 13.3 0.6 1.4 1 0 0 1 1 1 0 Spore Coat Protein U domain ANAPC4_WD40 PF12894.7 CDJ69976.1 - 0.00011 22.4 0.0 0.0026 18.0 0.0 2.8 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ69976.1 - 0.0016 19.2 1.7 12 6.9 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Mcl1_mid PF12341.8 CDJ69976.1 - 0.032 13.6 0.4 28 3.9 0.1 3.0 1 1 1 3 3 3 0 Minichromosome loss protein, Mcl1, middle region FUSC_2 PF13515.6 CDJ69977.1 - 7e-07 29.4 10.3 7e-07 29.4 10.3 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like Nup84_Nup100 PF04121.13 CDJ69978.1 - 4.2e-05 21.9 12.7 0.0042 15.2 0.1 4.0 5 0 0 5 5 5 3 Nuclear pore protein 84 / 107 Cuticle_1 PF08140.11 CDJ69978.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Crustacean cuticle protein repeat BMC PF00936.19 CDJ69978.1 - 0.55 10.3 4.3 0.15 12.1 0.2 2.3 2 0 0 2 2 2 0 BMC domain MMR_HSR1 PF01926.23 CDJ69979.1 - 2.3e-44 150.1 0.0 1e-22 80.4 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ69979.1 - 1.9e-21 76.2 0.0 7.8e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDJ69979.1 - 2.6e-19 69.6 0.3 3.6e-09 36.4 0.1 4.5 3 2 0 3 3 3 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CDJ69979.1 - 1.2e-11 44.3 0.0 1.3e-05 24.6 0.0 2.5 2 1 1 3 3 3 2 AIG1 family KH_dom-like PF14714.6 CDJ69979.1 - 1.1e-09 38.4 0.0 2.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Roc PF08477.13 CDJ69979.1 - 3.1e-08 33.9 0.2 0.59 10.4 0.0 4.2 3 1 1 4 4 4 3 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ69979.1 - 3.3e-06 26.8 0.0 0.17 11.5 0.0 3.9 2 2 0 2 2 2 2 Ras family RsgA_GTPase PF03193.16 CDJ69979.1 - 7.1e-06 26.0 0.0 2.3 8.1 0.0 4.3 4 0 0 4 4 4 1 RsgA GTPase Dynamin_N PF00350.23 CDJ69979.1 - 1.3e-05 25.3 0.0 0.15 12.1 0.0 3.3 4 0 0 4 4 4 2 Dynamin family MeaB PF03308.16 CDJ69979.1 - 5.6e-05 22.3 0.7 0.97 8.4 0.1 4.2 4 1 1 5 5 5 2 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CDJ69979.1 - 9.6e-05 22.0 0.2 0.082 12.5 0.1 3.3 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 CDJ69979.1 - 0.0036 16.8 0.0 19 4.6 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Arf PF00025.21 CDJ69979.1 - 0.0043 16.5 0.0 1.3 8.5 0.0 3.9 4 1 0 4 4 4 1 ADP-ribosylation factor family AAA_25 PF13481.6 CDJ69979.1 - 0.0074 15.9 0.4 8.4 5.9 0.1 3.5 3 1 0 3 3 3 1 AAA domain MCM PF00493.23 CDJ69979.1 - 0.014 14.5 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain TPP_enzyme_M PF00205.22 CDJ69979.1 - 0.092 12.5 0.3 1.1 9.0 0.0 2.5 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain ABC_tran PF00005.27 CDJ69979.1 - 0.16 12.5 0.0 5.1 7.6 0.0 2.6 3 0 0 3 3 2 0 ABC transporter Fcf2 PF08698.11 CDJ69980.1 - 1e-09 38.6 0.0 2.9e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing CHZ PF09649.10 CDJ69980.1 - 0.12 11.8 0.7 0.28 10.7 0.7 1.6 1 0 0 1 1 1 0 Histone chaperone domain CHZ DnaJ PF00226.31 CDJ69983.1 - 4.4e-15 55.6 0.0 1.1e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Phage_prot_Gp6 PF05133.14 CDJ69983.1 - 0.1 11.7 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like Cyt-b5 PF00173.28 CDJ69984.1 - 1.8e-22 79.2 0.0 2.4e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DEAD PF00270.29 CDJ69985.1 - 2.1e-41 141.6 0.0 3.8e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ69985.1 - 4.7e-27 94.5 0.0 1.2e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain mIF3 PF14877.6 CDJ69985.1 - 0.075 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial translation initiation factor EF-hand_8 PF13833.6 CDJ69986.1 - 2.5e-05 24.0 0.2 9.3e-05 22.2 0.1 1.8 1 1 1 2 2 2 1 EF-hand domain pair DUF3008 PF11450.8 CDJ69986.1 - 0.00014 22.0 0.1 0.00016 21.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknwon function (DUF3008) EF-hand_7 PF13499.6 CDJ69986.1 - 0.027 14.9 0.3 0.034 14.6 0.3 1.4 1 1 0 1 1 1 0 EF-hand domain pair LEM PF03020.15 CDJ69986.1 - 0.092 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 LEM domain AAA_lid_2 PF17863.1 CDJ69986.1 - 0.095 12.5 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA lid domain EF-hand_6 PF13405.6 CDJ69987.1 - 7.4e-08 31.7 0.3 2.1e-07 30.3 0.1 1.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CDJ69987.1 - 4.8e-07 30.1 0.1 9.8e-07 29.1 0.0 1.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ69987.1 - 8.1e-07 28.2 0.1 3.4e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CDJ69987.1 - 0.031 14.6 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain Milton PF12448.8 CDJ69987.1 - 0.031 14.4 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 Kinesin associated protein ThiS PF02597.20 CDJ69987.1 - 0.096 13.3 0.2 0.15 12.8 0.2 1.3 1 1 0 1 1 1 0 ThiS family V-SNARE_C PF12352.8 CDJ69988.1 - 7.6e-11 42.1 1.2 1.3e-10 41.4 1.2 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CDJ69988.1 - 0.00022 21.5 0.7 0.014 15.7 0.0 2.6 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Mito_carr PF00153.27 CDJ69989.1 - 9.9e-24 83.1 0.2 1.7e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF832 PF05734.11 CDJ69989.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Ribosomal_S8 PF00410.19 CDJ69990.1 - 3.2e-21 75.6 0.0 3.7e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 C2 PF00168.30 CDJ69991.1 - 1.4e-06 28.5 0.1 3.2e-05 24.1 0.1 2.5 1 1 0 1 1 1 1 C2 domain Chorion_2 PF03964.15 CDJ69991.1 - 0.0036 18.1 1.1 0.0036 18.1 1.1 4.3 4 1 1 5 5 5 1 Chorion family 2 Transglut_core PF01841.19 CDJ69991.1 - 0.094 13.2 0.2 0.29 11.6 0.2 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily L71 PF02448.15 CDJ69991.1 - 0.14 12.6 1.0 0.34 11.4 1.0 1.6 1 0 0 1 1 1 0 L71 family PIRT PF15099.6 CDJ69993.1 - 0.11 12.1 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family HemX PF04375.14 CDJ69995.1 - 0.02 14.2 2.6 0.031 13.6 2.6 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Methyltransf_8 PF05148.15 CDJ69996.1 - 1.1e-06 28.7 0.1 2e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase PseudoU_synth_2 PF00849.22 CDJ69997.1 - 1.6e-06 28.3 0.0 3.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase RRM_1 PF00076.22 CDJ69998.1 - 6e-17 61.2 0.0 8.7e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ69998.1 - 0.0044 17.1 0.0 0.026 14.6 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CDJ69998.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3373 PF11853.8 CDJ69999.1 - 0.19 10.8 0.1 0.25 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Sas10 PF09368.10 CDJ70000.1 - 2.6e-22 79.1 6.8 2.6e-22 79.1 6.8 2.6 2 1 1 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CDJ70000.1 - 1.4e-18 67.2 3.3 1.4e-18 67.2 3.3 2.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Gly_acyl_tr_N PF06021.11 CDJ70000.1 - 0.63 10.1 3.3 1.8 8.6 3.3 1.7 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase GAT PF03127.14 CDJ70000.1 - 3.1 8.2 7.4 0.4 11.0 1.1 2.8 3 0 0 3 3 3 0 GAT domain YebO PF13974.6 CDJ70000.1 - 6.1 7.0 11.5 0.31 11.1 3.1 3.3 3 0 0 3 3 3 0 YebO-like protein PhoLip_ATPase_C PF16212.5 CDJ70002.1 - 3.1e-52 177.8 19.1 3.1e-52 177.8 19.1 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDJ70002.1 - 1.7e-16 59.7 0.3 4.9e-16 58.2 0.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CDJ70002.1 - 3.9e-12 46.9 0.4 1.7e-07 31.8 0.1 3.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ70002.1 - 6.2e-07 29.4 0.0 4.5e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CDJ70002.1 - 4.3e-06 26.4 3.2 0.00015 21.4 0.0 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CDJ70002.1 - 0.038 13.7 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Androgen_recep PF02166.16 CDJ70003.1 - 0.0016 17.3 7.2 0.0016 17.3 7.2 11.6 4 3 5 9 9 9 1 Androgen receptor TFIIA PF03153.13 CDJ70003.1 - 0.002 18.2 7.2 0.002 18.2 7.2 5.5 3 1 2 5 5 5 2 Transcription factor IIA, alpha/beta subunit Methyltransf_25 PF13649.6 CDJ70003.1 - 0.13 12.9 0.0 0.72 10.6 0.0 2.4 1 0 0 1 1 1 0 Methyltransferase domain Las1 PF04031.13 CDJ70004.1 - 3.7e-34 118.1 3.7 3.7e-34 118.1 3.7 5.9 5 2 0 5 5 5 1 Las1-like WW PF00397.26 CDJ70005.1 - 1.2e-09 38.1 2.2 2e-09 37.4 2.2 1.4 1 0 0 1 1 1 1 WW domain YIF1 PF03878.15 CDJ70005.1 - 0.018 14.6 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 YIF1 Yip1 PF04893.17 CDJ70005.1 - 0.15 11.8 19.9 0.24 11.1 16.5 2.7 2 1 1 3 3 3 0 Yip1 domain Glyco_hydro_100 PF12899.7 CDJ70005.1 - 0.19 10.4 0.0 0.19 10.4 0.0 1.8 2 0 0 2 2 2 0 Alkaline and neutral invertase V_ATPase_I PF01496.19 CDJ70005.1 - 0.26 9.1 3.3 0.4 8.6 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BAF1_ABF1 PF04684.13 CDJ70005.1 - 0.42 9.6 6.8 0.48 9.4 1.5 2.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor TMEM51 PF15345.6 CDJ70005.1 - 1.3 8.8 13.4 0.12 12.2 4.0 2.9 3 0 0 3 3 3 0 Transmembrane protein 51 Wzz PF02706.15 CDJ70005.1 - 2.5 8.5 11.0 0.26 11.6 0.4 3.7 3 1 0 3 3 3 0 Chain length determinant protein DUF2981 PF11200.8 CDJ70005.1 - 7 6.3 7.1 17 5.0 7.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Pex2_Pex12 PF04757.14 CDJ70006.1 - 5.1e-05 23.0 6.4 0.07 12.7 0.0 2.8 2 1 0 2 2 2 2 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 CDJ70006.1 - 8.6e-05 22.6 10.6 8.6e-05 22.6 10.6 2.6 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING DUF4228 PF14009.6 CDJ70006.1 - 0.0001 22.7 6.0 0.0028 18.1 0.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4228) Nha1_C PF08619.10 CDJ70006.1 - 0.00017 21.0 6.1 0.0059 15.9 2.6 2.1 2 0 0 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus DUF755 PF05501.11 CDJ70006.1 - 0.00022 21.5 13.4 0.00022 21.5 13.4 4.2 3 1 0 3 3 2 1 Domain of unknown function (DUF755) MID_MedPIWI PF18296.1 CDJ70006.1 - 0.0021 17.9 15.1 0.032 14.0 2.6 2.2 2 0 0 2 2 2 2 MID domain of medPIWI zf-RING_UBOX PF13445.6 CDJ70006.1 - 0.011 15.7 12.8 0.027 14.5 12.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ70006.1 - 0.034 14.5 13.1 0.034 14.5 13.1 2.2 2 0 0 2 2 1 0 Ring finger domain MAP17 PF15807.5 CDJ70006.1 - 0.041 14.1 1.8 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SPX PF03105.19 CDJ70006.1 - 0.084 12.8 15.4 0.47 10.3 15.4 2.1 1 1 0 1 1 1 0 SPX domain TFIIA PF03153.13 CDJ70006.1 - 1.1 9.2 21.5 0.88 9.5 10.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sec3_C PF09763.9 CDJ70006.1 - 1.4 7.2 11.3 0.13 10.6 2.1 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec3 DUF1645 PF07816.11 CDJ70006.1 - 1.5 9.3 28.5 0.093 13.3 7.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) Kinesin_assoc PF16183.5 CDJ70006.1 - 3.2 7.8 5.0 8.3 6.5 0.3 2.4 2 0 0 2 2 2 0 Kinesin-associated Apt1 PF10351.9 CDJ70006.1 - 3.8 6.3 17.7 2.7 6.8 4.9 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain EphA2_TM PF14575.6 CDJ70006.1 - 5.2 8.0 6.3 21 6.1 0.3 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 CDJ70008.1 - 0.029 15.3 1.6 0.029 15.3 1.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Serinc PF03348.15 CDJ70008.1 - 0.15 10.9 3.8 0.17 10.8 3.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 CDJ70008.1 - 0.22 10.3 4.1 0.27 9.9 4.1 1.2 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ70008.1 - 0.22 11.1 20.7 0.14 11.7 7.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1117 PF06547.12 CDJ70008.1 - 1.4 9.4 5.5 9 6.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Ctr PF04145.15 CDJ70008.1 - 1.5 9.4 8.3 4.7 7.8 8.2 1.8 1 1 0 1 1 1 0 Ctr copper transporter family TFIIA PF03153.13 CDJ70008.1 - 1.9 8.4 18.2 2.5 8.0 18.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ70008.1 - 7.1 6.9 18.7 29 4.9 18.7 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ70010.1 - 0.28 10.8 5.4 0.061 12.9 0.9 2.1 2 0 0 2 2 2 0 Spt20 family DUF1645 PF07816.11 CDJ70010.1 - 0.34 11.5 8.9 0.16 12.5 6.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) IMUP PF15761.5 CDJ70010.1 - 0.73 10.5 9.2 2.5 8.9 9.2 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF3123 PF11321.8 CDJ70010.1 - 1.2 9.8 5.6 0.3 11.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Herpes_pp85 PF04637.12 CDJ70010.1 - 1.7 7.0 3.6 2.3 6.5 3.6 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4667 PF15700.5 CDJ70010.1 - 2.2 8.3 12.5 1.4 8.9 10.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4667) DUF3446 PF11928.8 CDJ70010.1 - 4.4 7.7 18.3 0.28 11.5 11.9 2.2 2 1 0 2 2 2 0 Early growth response N-terminal domain FAST_1 PF06743.15 CDJ70012.1 - 0.004 17.1 0.2 3.9 7.5 0.0 4.3 4 1 1 5 5 5 3 FAST kinase-like protein, subdomain 1 Peptidase_M16_C PF05193.21 CDJ70014.1 - 3e-26 92.6 0.1 1.9e-14 54.1 0.0 3.6 2 2 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDJ70014.1 - 5e-15 55.8 0.3 3.7e-13 49.7 0.4 2.7 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) YicC_N PF03755.13 CDJ70014.1 - 0.047 14.2 0.0 0.55 10.7 0.0 2.5 2 0 0 2 2 2 0 YicC-like family, N-terminal region Trep_dent_lipo PF09710.10 CDJ70014.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) ALAD PF00490.21 CDJ70015.1 - 6.8e-130 432.9 0.0 8e-130 432.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Cnd2 PF05786.14 CDJ70015.1 - 0.13 10.9 2.9 0.17 10.5 2.9 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Nop14 PF04147.12 CDJ70015.1 - 0.62 8.2 5.8 0.78 7.9 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDJ70015.1 - 0.9 7.7 3.0 1.2 7.3 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 CDJ70015.1 - 1.2 8.8 7.5 2 8.1 7.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 CDJ70015.1 - 3 8.0 14.0 5.5 7.2 14.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 YL1 PF05764.13 CDJ70015.1 - 3.3 7.8 8.1 5.7 7.0 8.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 CDJ70015.1 - 9.2 5.5 11.7 14 4.9 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein AP2 PF00847.20 CDJ70016.1 - 3.3e-06 27.2 0.3 1.1e-05 25.5 0.3 1.9 1 0 0 1 1 1 1 AP2 domain Methyltransf_23 PF13489.6 CDJ70017.1 - 3.9e-10 39.8 0.0 1.3e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ70017.1 - 1.6e-08 34.5 0.0 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ70017.1 - 1.7e-08 35.1 0.0 1.7e-07 31.8 0.0 2.3 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ70017.1 - 6.4e-08 33.2 0.0 1e-05 26.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ70017.1 - 0.00094 19.9 0.0 0.003 18.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Corona_nucleoca PF00937.18 CDJ70017.1 - 0.015 14.4 0.5 0.021 13.9 0.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein MTS PF05175.14 CDJ70017.1 - 0.019 14.5 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Pox_MCEL PF03291.16 CDJ70017.1 - 0.045 12.9 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme EF-hand_1 PF00036.32 CDJ70019.1 - 6.8e-05 22.1 0.0 0.00025 20.4 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CDJ70019.1 - 8.3e-05 22.2 0.0 0.00036 20.2 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CDJ70019.1 - 0.016 15.6 0.2 0.068 13.6 0.0 2.2 3 0 0 3 3 3 0 EF-hand domain pair HSP90 PF00183.18 CDJ70022.1 - 1.2e-233 776.7 37.3 1.6e-233 776.3 37.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CDJ70022.1 - 3.1e-16 59.9 0.0 6e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ70022.1 - 8e-10 38.7 0.1 2.4e-09 37.1 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 CDJ70022.1 - 0.0039 17.2 0.2 0.016 15.3 0.2 2.0 1 0 0 1 1 1 1 Tumour suppressor protein Cofac_haem_bdg PF04187.13 CDJ70022.1 - 0.12 12.3 1.6 0.34 10.9 0.1 2.5 2 1 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN Zip PF02535.22 CDJ70022.1 - 0.18 11.0 3.2 0.29 10.3 3.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.16 CDJ70022.1 - 0.47 9.6 7.3 0.91 8.7 7.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 CDJ70022.1 - 2.3 8.6 10.6 4.8 7.6 10.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 CDJ70022.1 - 2.8 6.6 7.0 4.3 6.0 7.0 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CDJ70022.1 - 4.8 5.3 17.2 7.9 4.6 17.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SUIM_assoc PF16619.5 CDJ70023.1 - 0.0034 17.4 4.9 0.0034 17.4 4.9 3.1 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 RAI16-like PF10257.9 CDJ70023.1 - 0.026 13.4 0.0 0.078 11.8 0.0 1.6 1 1 0 1 1 1 0 Retinoic acid induced 16-like protein SUIM_assoc PF16619.5 CDJ70024.1 - 0.28 11.3 65.0 0.095 12.8 1.3 6.9 6 0 0 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 SPX PF03105.19 CDJ70026.1 - 3.8e-07 30.4 7.6 0.001 19.1 0.0 2.4 1 1 1 2 2 2 1 SPX domain DUF2722 PF10846.8 CDJ70026.1 - 0.00096 18.2 2.6 0.00096 18.2 2.6 5.2 2 1 3 5 5 5 1 Protein of unknown function (DUF2722) DUF3853 PF12964.7 CDJ70026.1 - 0.011 15.9 0.1 0.011 15.9 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3853) Hydrolase PF00702.26 CDJ70026.1 - 0.054 13.8 2.3 0.071 13.4 0.0 2.4 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Tmp39 PF10271.9 CDJ70026.1 - 0.12 11.3 1.7 0.16 11.0 0.4 1.8 1 1 0 1 1 1 0 Putative transmembrane protein Phage_holin_5_2 PF16079.5 CDJ70026.1 - 0.48 10.8 1.5 31 5.0 0.1 3.1 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V E1-E2_ATPase PF00122.20 CDJ70027.1 - 5.6e-14 52.1 0.0 5.6e-14 52.1 0.0 4.5 6 0 0 6 6 6 2 E1-E2 ATPase Hydrolase PF00702.26 CDJ70027.1 - 0.015 15.6 0.0 0.015 15.6 0.0 3.8 5 0 0 5 5 5 0 haloacid dehalogenase-like hydrolase TFIIA PF03153.13 CDJ70028.1 - 0.012 15.6 54.7 0.031 14.3 25.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HNOBA PF07701.14 CDJ70028.1 - 0.014 14.8 5.7 1.1 8.7 4.3 2.5 2 0 0 2 2 2 0 Heme NO binding associated MecA PF05389.12 CDJ70028.1 - 0.026 14.2 6.9 0.099 12.3 0.8 2.4 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) eIF-3_zeta PF05091.12 CDJ70028.1 - 0.036 13.1 16.6 0.032 13.2 3.5 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 CDJ70028.1 - 0.056 12.9 13.1 0.38 10.2 6.8 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SAPS PF04499.15 CDJ70028.1 - 0.069 11.9 7.9 0.77 8.5 6.5 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF1645 PF07816.11 CDJ70028.1 - 0.077 13.6 31.8 0.034 14.7 15.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) DUF4770 PF15994.5 CDJ70028.1 - 0.083 13.1 18.9 0.17 12.1 6.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) AAA_23 PF13476.6 CDJ70028.1 - 0.11 13.0 16.6 0.09 13.3 5.8 2.3 2 0 0 2 2 2 0 AAA domain SLC12 PF03522.15 CDJ70028.1 - 0.14 11.2 14.4 0.074 12.1 5.2 2.1 2 0 0 2 2 2 0 Solute carrier family 12 TERB2 PF15101.6 CDJ70028.1 - 0.14 12.2 0.1 0.14 12.2 0.1 3.0 3 0 0 3 3 3 0 Telomere-associated protein TERB2 BRF1 PF07741.13 CDJ70028.1 - 0.21 11.9 17.7 0.39 11.1 1.8 3.0 3 0 0 3 3 3 0 Brf1-like TBP-binding domain RR_TM4-6 PF06459.12 CDJ70028.1 - 0.27 11.0 14.0 0.87 9.4 5.9 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SPX PF03105.19 CDJ70028.1 - 0.42 10.5 34.3 1.3 8.9 21.4 2.2 2 0 0 2 2 2 0 SPX domain Lin-8 PF03353.15 CDJ70028.1 - 0.5 9.9 29.6 0.13 11.8 16.1 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF2828 PF11443.8 CDJ70028.1 - 0.86 7.6 12.0 0.55 8.3 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF3464 PF11947.8 CDJ70028.1 - 2.3 7.9 23.6 0.3 10.8 1.7 2.8 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 Tim54 PF11711.8 CDJ70028.1 - 2.5 6.8 15.4 0.86 8.3 6.2 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 V_ATPase_I PF01496.19 CDJ70028.1 - 3 5.7 17.3 1.1 7.1 8.5 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Apt1 PF10351.9 CDJ70028.1 - 4.5 6.0 28.4 0.19 10.5 16.8 2.3 2 1 0 2 2 2 0 Golgi-body localisation protein domain DUF2126 PF09899.9 CDJ70028.1 - 5.1 5.0 12.7 0.34 8.9 3.0 2.0 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) Otopetrin PF03189.13 CDJ70028.1 - 5.8 5.6 6.7 26 3.5 4.8 2.1 2 0 0 2 2 2 0 Otopetrin DUF3086 PF11285.8 CDJ70028.1 - 6.1 5.9 16.6 1.4 7.9 6.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) TFB6 PF17110.5 CDJ70028.1 - 6.3 6.5 8.5 12 5.6 3.4 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Lung_7-TM_R PF06814.13 CDJ70030.1 - 1.7e-16 60.4 0.3 2.4e-16 59.8 0.3 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 CDJ70030.1 - 0.0013 18.2 1.0 0.0027 17.2 1.0 1.5 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain CCSAP PF15748.5 CDJ70030.1 - 0.065 13.4 9.7 1.2 9.2 2.8 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Bindin PF02084.15 CDJ70030.1 - 5.4 7.2 16.4 2.3 8.4 0.4 2.6 2 0 0 2 2 2 0 Bindin SMN PF06003.12 CDJ70031.1 - 0.36 10.1 10.9 0.53 9.5 10.9 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Miga PF10265.9 CDJ70031.1 - 4.2 6.2 12.9 5 6.0 12.9 1.1 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 CDJ70031.1 - 7 5.4 12.5 7.6 5.3 12.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain FtsJ PF01728.19 CDJ70032.1 - 7.7e-31 107.6 0.0 2.1e-30 106.1 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CDJ70032.1 - 2.3e-22 79.6 8.0 9.8e-19 67.8 8.0 7.7 4 2 3 7 7 7 3 Domain of unknown function (DUF3381) DUF3399 PF11879.8 CDJ70033.1 - 7.6 6.9 7.6 9.4 6.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) V_ATPase_I PF01496.19 CDJ70035.1 - 0.00017 19.7 0.5 0.00017 19.7 0.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF2828 PF11443.8 CDJ70035.1 - 0.00093 17.4 2.7 0.00093 17.4 2.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) MecA PF05389.12 CDJ70035.1 - 0.0029 17.3 3.8 0.0031 17.2 3.8 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) SID-1_RNA_chan PF13965.6 CDJ70035.1 - 0.0053 15.2 0.0 0.0066 14.9 0.0 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DUF1980 PF09323.10 CDJ70035.1 - 0.0058 16.6 5.2 0.0091 15.9 5.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1980) IMPDH PF00478.25 CDJ70035.1 - 0.0096 15.0 0.7 0.013 14.6 0.7 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CDC45 PF02724.14 CDJ70035.1 - 0.01 14.2 3.7 0.013 13.9 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 CDJ70035.1 - 0.03 14.5 5.7 0.036 14.2 5.7 1.1 1 0 0 1 1 1 0 DDHD domain DUF4746 PF15928.5 CDJ70035.1 - 0.037 13.4 4.5 0.045 13.2 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CPSF100_C PF13299.6 CDJ70035.1 - 0.051 13.8 6.8 0.068 13.4 6.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PEN-2 PF10251.9 CDJ70035.1 - 0.058 13.8 0.1 0.058 13.8 0.1 2.9 2 2 1 3 3 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF719 PF05334.13 CDJ70035.1 - 0.061 13.5 7.5 0.09 13.0 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) THOC2_N PF16134.5 CDJ70035.1 - 0.065 11.9 5.6 0.085 11.5 5.6 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus TFIIA PF03153.13 CDJ70035.1 - 0.091 12.7 32.6 0.12 12.4 32.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FHIPEP PF00771.20 CDJ70035.1 - 0.11 10.9 5.5 0.15 10.5 5.5 1.2 1 0 0 1 1 1 0 FHIPEP family NARP1 PF12569.8 CDJ70035.1 - 0.14 11.1 10.1 0.17 10.8 10.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PAT1 PF09770.9 CDJ70035.1 - 0.14 10.4 19.5 0.15 10.3 19.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pal1 PF08316.11 CDJ70035.1 - 0.24 12.2 3.4 0.32 11.7 3.4 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Suf PF05843.14 CDJ70035.1 - 0.28 11.2 15.4 0.32 11.0 15.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 CDJ70035.1 - 0.29 11.1 16.8 0.41 10.7 16.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SpoIIP PF07454.11 CDJ70035.1 - 0.34 10.3 13.4 0.45 9.9 13.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ70035.1 - 0.35 9.8 17.1 0.43 9.5 17.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tim54 PF11711.8 CDJ70035.1 - 0.62 8.8 13.9 0.84 8.4 13.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Cellulose_synt PF03552.14 CDJ70035.1 - 0.78 8.2 1.8 0.99 7.8 1.8 1.2 1 0 0 1 1 1 0 Cellulose synthase DUF2126 PF09899.9 CDJ70035.1 - 0.95 7.5 8.2 1.2 7.2 8.2 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Connexin PF00029.19 CDJ70035.1 - 1.1 8.9 9.9 1.8 8.2 9.9 1.3 1 0 0 1 1 1 0 Connexin DUF5385 PF17359.2 CDJ70035.1 - 1.6 8.3 17.5 2.3 7.7 17.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) RR_TM4-6 PF06459.12 CDJ70035.1 - 1.7 8.4 14.1 2.5 7.9 14.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HemX PF04375.14 CDJ70035.1 - 1.7 7.9 27.2 2.4 7.3 27.2 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Peptidase_U4 PF03419.13 CDJ70035.1 - 2.5 7.3 9.4 2.9 7.1 0.1 2.2 2 0 0 2 2 2 0 Sporulation factor SpoIIGA TFB6 PF17110.5 CDJ70035.1 - 2.9 7.6 8.3 4.5 7.0 8.3 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Eapp_C PF10238.9 CDJ70035.1 - 3 7.9 15.2 4.8 7.3 15.2 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Otopetrin PF03189.13 CDJ70035.1 - 3.2 6.5 8.8 38 2.9 0.0 2.0 2 0 0 2 2 2 0 Otopetrin Med15 PF09606.10 CDJ70035.1 - 3.3 6.3 34.2 4.2 5.9 34.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Conotoxin PF02950.17 CDJ70035.1 - 3.6 8.7 14.0 6.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Conotoxin DUF3408 PF11888.8 CDJ70035.1 - 4 7.6 16.9 6 7.0 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) EIIBC-GUT_N PF03612.14 CDJ70035.1 - 4.6 6.9 14.2 6.7 6.4 14.2 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4770 PF15994.5 CDJ70035.1 - 5.1 7.3 20.2 51 4.0 18.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) CobT PF06213.12 CDJ70035.1 - 6.9 6.0 20.5 10 5.4 20.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.6 CDJ70035.1 - 7.2 6.3 11.2 13 5.5 8.4 2.1 2 0 0 2 2 2 0 FAM176 family Paf1 PF03985.13 CDJ70035.1 - 7.8 5.4 20.2 9.9 5.0 20.2 1.1 1 0 0 1 1 1 0 Paf1 ABC2_membrane_3 PF12698.7 CDJ70035.1 - 8.2 5.4 8.3 3.2 6.8 0.4 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF3464 PF11947.8 CDJ70035.1 - 8.3 6.2 17.6 20 4.9 17.6 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TMEM51 PF15345.6 CDJ70035.1 - 8.7 6.1 19.4 15 5.3 19.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Zip PF02535.22 CDJ70035.1 - 8.8 5.4 6.5 0.9 8.7 2.1 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter Motile_Sperm PF00635.26 CDJ70036.1 - 1.3e-20 73.3 0.0 2.4e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TPR_MLP1_2 PF07926.12 CDJ70036.1 - 0.0069 16.5 3.0 0.0069 16.5 3.0 1.7 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein BRE1 PF08647.11 CDJ70036.1 - 0.011 15.7 0.7 0.02 15.0 0.7 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase TraT PF05818.12 CDJ70036.1 - 0.013 15.2 2.1 0.019 14.7 2.1 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF5383 PF17355.2 CDJ70036.1 - 0.082 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Peptidase_S8 PF00082.22 CDJ70036.1 - 0.12 11.6 4.1 0.17 11.1 4.1 1.3 1 0 0 1 1 1 0 Subtilase family CCDC106 PF15794.5 CDJ70036.1 - 0.62 9.7 4.2 0.36 10.5 2.3 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 Tic110 PF16940.5 CDJ70036.1 - 1.5 7.2 8.9 1.9 6.8 8.9 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Peptidase_M22 PF00814.25 CDJ70037.1 - 2.2e-17 63.7 6.9 4e-07 30.0 0.0 5.3 4 1 0 5 5 5 5 Glycoprotease family DUF2722 PF10846.8 CDJ70037.1 - 0.00063 18.8 0.2 0.00063 18.8 0.2 6.3 4 3 2 6 6 6 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ70037.1 - 0.0095 16.0 48.7 0.0095 16.0 48.7 4.5 3 2 0 4 4 4 2 Transcription factor IIA, alpha/beta subunit SAGA-Tad1 PF12767.7 CDJ70037.1 - 0.024 14.4 29.7 0.022 14.5 10.7 4.0 4 0 0 4 4 4 0 Transcriptional regulator of RNA polII, SAGA, subunit SPX PF03105.19 CDJ70037.1 - 0.7 9.8 37.7 0.056 13.4 7.2 3.2 3 0 0 3 3 3 0 SPX domain Presenilin PF01080.17 CDJ70037.1 - 2.7 6.7 46.9 0.62 8.8 25.7 4.0 4 0 0 4 4 4 0 Presenilin AUX_IAA PF02309.16 CDJ70037.1 - 3.2 7.6 22.1 0.54 10.1 7.6 3.8 4 0 0 4 4 4 0 AUX/IAA family SUIM_assoc PF16619.5 CDJ70038.1 - 7.9e-07 29.0 54.2 0.011 15.8 2.4 5.0 4 0 0 4 4 4 4 Unstructured region C-term to UIM in Ataxin3 Methyltransf_15 PF09445.10 CDJ70038.1 - 1.5e-05 24.6 0.2 2.8e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Spt20 PF12090.8 CDJ70038.1 - 3.7e-05 23.5 58.6 0.009 15.7 5.4 4.2 4 0 0 4 4 4 4 Spt20 family DUF2722 PF10846.8 CDJ70038.1 - 0.00078 18.5 46.9 0.039 12.9 3.3 4.1 4 0 0 4 4 4 3 Protein of unknown function (DUF2722) MMS22L_N PF14910.6 CDJ70038.1 - 0.12 10.8 0.1 0.21 10.0 0.1 1.3 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal DUF4578 PF15147.6 CDJ70038.1 - 2.5 9.0 34.5 4.5 8.2 7.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4578) CTU2 PF10288.9 CDJ70038.1 - 2.7 8.3 23.3 1.3 9.3 1.4 4.4 4 0 0 4 4 4 0 Cytoplasmic tRNA 2-thiolation protein 2 LAT PF15234.6 CDJ70038.1 - 4.1 7.1 7.5 1.5 8.5 3.4 2.5 2 0 0 2 2 2 0 Linker for activation of T-cells ubiquitin PF00240.23 CDJ70040.1 - 1.9e-19 69.1 0.0 1.9e-19 69.1 0.0 1.6 2 0 0 2 2 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ70040.1 - 2.1e-06 27.5 0.0 2.1e-06 27.5 0.0 1.7 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like SUIM_assoc PF16619.5 CDJ70040.1 - 4.6e-05 23.4 7.1 8.7e-05 22.5 7.1 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Rad60-SLD_2 PF13881.6 CDJ70040.1 - 6.6e-05 23.0 1.3 0.00011 22.2 1.3 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDJ70040.1 - 8.4e-05 23.1 0.8 0.00013 22.5 0.8 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Roughex PF06020.11 CDJ70040.1 - 0.00033 19.9 1.8 0.00033 19.9 1.8 1.6 2 0 0 2 2 2 1 Drosophila roughex protein TBK1_ULD PF18396.1 CDJ70040.1 - 0.0047 16.8 0.0 0.0047 16.8 0.0 1.7 2 0 0 2 2 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 CDJ70040.1 - 0.0056 17.1 0.1 0.015 15.7 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Spt20 PF12090.8 CDJ70040.1 - 0.015 14.9 12.3 0.023 14.3 12.3 1.3 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 CDJ70040.1 - 0.02 15.6 3.4 0.02 15.6 3.4 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ70040.1 - 0.022 14.8 1.0 0.02 14.9 1.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) YukD PF08817.10 CDJ70040.1 - 0.11 13.2 0.1 1.1 9.9 0.0 2.4 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD TFIIA PF03153.13 CDJ70040.1 - 0.11 12.5 13.2 0.14 12.1 13.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ70040.1 - 0.12 11.3 11.4 0.17 10.8 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Coilin_N PF15862.5 CDJ70040.1 - 0.25 11.1 3.3 0.56 10.0 3.3 1.5 1 0 0 1 1 1 0 Coilin N-terminus DUF4834 PF16118.5 CDJ70040.1 - 0.43 11.6 3.8 0.78 10.7 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3597 PF12200.8 CDJ70040.1 - 0.62 10.6 8.5 1.6 9.3 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) RAB3GAP2_N PF14655.6 CDJ70040.1 - 1 8.5 5.5 1.4 8.0 5.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4726 PF15855.5 CDJ70041.1 - 0.13 12.5 0.7 0.53 10.5 0.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) V-SNARE PF05008.15 CDJ70041.1 - 0.98 9.8 10.4 1.1 9.7 0.2 4.3 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus LppX_LprAFG PF07161.13 CDJ70042.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 LppX_LprAFG lipoprotein adh_short PF00106.25 CDJ70042.1 - 0.12 11.8 2.3 0.33 10.4 0.1 2.4 2 0 0 2 2 2 0 short chain dehydrogenase Polo_box_3 PF18544.1 CDJ70042.1 - 0.14 12.8 2.1 0.46 11.1 0.1 2.8 3 0 0 3 3 3 0 Polo box domain CM_2 PF01817.21 CDJ70042.1 - 0.37 11.2 8.2 0.24 11.8 0.2 3.9 3 1 0 3 3 3 0 Chorismate mutase type II DUF948 PF06103.11 CDJ70042.1 - 2.4 8.5 6.6 6.6 7.1 0.4 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ank_2 PF12796.7 CDJ70043.1 - 7.1e-21 74.6 0.1 2.7e-09 37.5 0.1 3.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ70043.1 - 6.9e-16 58.1 0.2 1.2e-06 28.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ70043.1 - 2.2e-15 56.8 0.9 2.3e-08 34.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ70043.1 - 3.1e-15 54.7 0.4 0.0031 17.9 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 CDJ70043.1 - 2.4e-13 49.9 0.1 0.012 16.1 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat SR-25 PF10500.9 CDJ70043.1 - 6.7e-05 22.6 5.7 6.7e-05 22.6 5.7 2.6 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ70043.1 - 0.00031 19.0 6.3 0.00031 19.0 6.3 1.8 2 0 0 2 2 2 1 AF-4 proto-oncoprotein DUF3446 PF11928.8 CDJ70043.1 - 0.0028 17.9 9.5 0.0028 17.9 9.5 3.4 3 1 0 3 3 3 1 Early growth response N-terminal domain SMN PF06003.12 CDJ70043.1 - 0.35 10.1 2.7 0.66 9.2 2.7 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) GREB1 PF15782.5 CDJ70043.1 - 6 3.8 9.8 9.7 3.1 9.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4763 PF15960.5 CDJ70045.1 - 9.9e-05 21.8 7.0 9.9e-05 21.8 7.0 6.9 6 2 1 7 7 7 1 Domain of unknown function (DUF4763) RTC_insert PF05189.13 CDJ70045.1 - 0.069 13.7 0.0 0.069 13.7 0.0 2.9 3 1 0 3 3 3 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain SUIM_assoc PF16619.5 CDJ70045.1 - 3 8.0 0.0 3 8.0 0.0 10.6 5 5 1 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 Myosin_head PF00063.21 CDJ70046.1 - 4.7e-110 368.8 0.2 6e-110 368.5 0.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CDJ70046.1 - 0.0025 18.2 0.0 0.009 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ70046.1 - 0.0063 16.8 0.1 0.014 15.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 CDJ70046.1 - 0.025 14.6 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activat PF00158.26 CDJ70046.1 - 0.028 14.1 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Myosin_N PF02736.19 CDJ70046.1 - 0.055 13.3 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_24 PF13479.6 CDJ70046.1 - 0.079 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ70046.1 - 0.13 11.7 0.0 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Actin PF00022.19 CDJ70047.1 - 3.9e-16 58.7 0.0 4.2e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Actin ALP_N PF17989.1 CDJ70047.1 - 0.067 13.4 0.0 0.088 13.0 0.0 1.2 1 0 0 1 1 1 0 Actin like proteins N terminal domain Hydrolase_4 PF12146.8 CDJ70048.1 - 2.1e-12 46.8 0.0 2.7e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ70048.1 - 9.4e-08 32.9 2.2 1.2e-07 32.6 2.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ70048.1 - 1.4e-05 24.9 0.1 1.9e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CDJ70048.1 - 0.0059 16.2 0.0 0.0075 15.9 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 CDJ70048.1 - 0.0063 16.2 0.0 0.052 13.2 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Peptidase_M16 PF00675.20 CDJ70049.1 - 5.6e-43 146.5 0.6 4.3e-40 137.1 0.5 2.9 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDJ70049.1 - 7.3e-29 101.1 0.0 1.4e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Cys_Met_Meta_PP PF01053.20 CDJ70052.1 - 3.2e-112 374.8 0.0 1.2e-62 211.7 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CDJ70052.1 - 1.1e-05 25.0 0.2 2.8e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CDJ70052.1 - 3.8e-05 23.0 0.0 7.5e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 CDJ70052.1 - 0.052 12.1 0.0 0.21 10.1 0.0 1.9 2 0 0 2 2 2 0 Methionine gamma-lyase Spt20 PF12090.8 CDJ70054.1 - 0.4 10.2 10.7 0.4 10.3 10.7 1.0 1 0 0 1 1 1 0 Spt20 family Metallopep PF12044.8 CDJ70055.1 - 0.38 9.3 4.4 0.47 9.0 4.4 1.1 1 0 0 1 1 1 0 Putative peptidase family KH_6 PF15985.5 CDJ70057.1 - 1.5e-07 31.6 0.1 2.8e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 KH domain SLX9 PF15341.6 CDJ70057.1 - 0.0053 17.1 3.3 0.0053 17.1 3.3 4.7 3 1 0 4 4 4 1 Ribosome biogenesis protein SLX9 Spore_YhcN_YlaJ PF09580.10 CDJ70057.1 - 0.21 11.7 19.8 0.26 11.4 2.0 3.5 2 1 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF4775 PF16001.5 CDJ70059.1 - 1.7 7.9 4.3 2.5 7.4 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Patched PF02460.18 CDJ70059.1 - 5.2 5.0 14.7 6.9 4.6 14.7 1.1 1 0 0 1 1 1 0 Patched family Carbam_trans_N PF02543.15 CDJ70060.1 - 0.12 12.0 0.4 0.31 10.7 0.1 1.7 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus CTP_transf_like PF01467.26 CDJ70061.1 - 3.9e-10 40.1 9.1 0.0011 19.1 8.4 2.9 1 1 1 2 2 2 2 Cytidylyltransferase-like Presenilin PF01080.17 CDJ70061.1 - 0.00011 21.1 15.6 0.00011 21.1 15.6 3.4 3 1 0 4 4 4 1 Presenilin RskA PF10099.9 CDJ70062.1 - 0.003 17.9 6.7 0.003 17.9 6.7 4.0 1 1 1 2 2 1 1 Anti-sigma-K factor rskA TMEM51 PF15345.6 CDJ70062.1 - 0.0053 16.6 12.2 0.03 14.2 7.9 2.7 3 0 0 3 3 3 1 Transmembrane protein 51 ATP-synt_E PF05680.12 CDJ70062.1 - 0.013 15.8 8.1 0.013 15.8 8.1 2.7 3 0 0 3 3 2 0 ATP synthase E chain DUF4207 PF13904.6 CDJ70062.1 - 0.081 12.6 33.0 0.093 12.4 2.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) DUF1980 PF09323.10 CDJ70062.1 - 0.23 11.3 9.3 0.22 11.4 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF913 PF06025.12 CDJ70062.1 - 0.42 9.5 7.8 2.6 6.9 5.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF719 PF05334.13 CDJ70062.1 - 0.67 10.1 12.1 0.75 10.0 6.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) FliP PF00813.20 CDJ70062.1 - 1.2 9.0 11.1 0.4 10.5 6.3 2.0 2 0 0 2 2 2 0 FliP family Ribosomal_60s PF00428.19 CDJ70062.1 - 1.4 9.6 35.0 0.62 10.7 11.9 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein YABBY PF04690.13 CDJ70062.1 - 1.8 9.1 15.4 0.8 10.2 8.7 2.2 2 0 0 2 2 2 0 YABBY protein Sec16 PF12932.7 CDJ70062.1 - 2.3 8.8 9.6 31 5.2 5.9 2.5 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region DUF702 PF05142.12 CDJ70062.1 - 2.4 8.6 18.9 0.72 10.3 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF702) TetR_C_11 PF16859.5 CDJ70062.1 - 2.5 8.4 14.1 9.7 6.5 2.7 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Dynamin_N PF00350.23 CDJ70062.1 - 3.1 7.8 8.4 2.7 8.0 3.6 2.1 2 0 0 2 2 2 0 Dynamin family Pex14_N PF04695.13 CDJ70062.1 - 4.5 7.9 33.3 7.4 7.2 6.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Band_3_cyto PF07565.13 CDJ70062.1 - 4.8 6.9 14.2 32 4.2 10.8 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Peptidase_S49_N PF08496.10 CDJ70062.1 - 5.3 7.1 12.8 8 6.5 8.4 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FAM176 PF14851.6 CDJ70062.1 - 5.4 6.7 9.3 1.9 8.2 4.7 2.1 2 0 0 2 2 2 0 FAM176 family Peptidase_S15 PF02129.18 CDJ70062.1 - 5.9 6.4 18.9 0.25 10.9 6.9 2.2 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) SUIM_assoc PF16619.5 CDJ70063.1 - 0.018 15.1 8.8 0.018 15.1 8.8 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2477 PF10631.9 CDJ70063.1 - 1.5 9.5 11.0 2 9.1 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Tctex-1 PF03645.13 CDJ70064.1 - 6e-12 45.7 0.1 6.8e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family Abhydrolase_4 PF08386.10 CDJ70064.1 - 0.093 12.9 0.3 0.21 11.7 0.3 1.6 1 1 0 1 1 1 0 TAP-like protein TFIIA PF03153.13 CDJ70065.1 - 0.0052 16.8 26.1 0.0052 16.8 26.1 5.6 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit RITA PF17066.5 CDJ70066.1 - 0.86 9.1 12.3 1 8.9 12.3 1.1 1 0 0 1 1 1 0 RBPJ-interacting and tubulin associated protein DUF572 PF04502.13 CDJ70066.1 - 3.9 7.0 17.4 5 6.7 17.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SARAF PF06682.12 CDJ70066.1 - 4.4 6.9 17.1 4.9 6.7 17.1 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2828 PF11443.8 CDJ70066.1 - 4.7 5.2 13.6 5.3 5.0 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ70066.1 - 5.3 5.7 21.3 5.5 5.6 21.3 1.1 1 0 0 1 1 1 0 Presenilin CGI-121 PF08617.10 CDJ70067.1 - 3.8e-11 43.4 0.1 3.8e-11 43.4 0.1 2.6 3 0 0 3 3 3 1 Kinase binding protein CGI-121 Spt20 PF12090.8 CDJ70067.1 - 9.8e-05 22.1 47.8 0.0027 17.3 18.0 2.2 2 0 0 2 2 2 2 Spt20 family Apt1 PF10351.9 CDJ70067.1 - 0.00016 20.7 4.0 0.00016 20.7 4.0 3.1 3 1 0 3 3 2 1 Golgi-body localisation protein domain TFIIA PF03153.13 CDJ70067.1 - 0.0004 20.5 45.4 0.0044 17.1 17.1 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.11 CDJ70067.1 - 0.0053 17.0 25.8 0.0053 17.0 25.8 4.4 4 0 0 4 4 3 1 Domain of unknown function (DUF755) Ndc1_Nup PF09531.10 CDJ70067.1 - 0.0077 15.0 16.4 0.01 14.6 5.2 2.4 2 0 0 2 2 2 2 Nucleoporin protein Ndc1-Nup Mit_KHE1 PF10173.9 CDJ70067.1 - 0.01 15.9 2.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related PNISR PF15996.5 CDJ70067.1 - 0.011 16.0 0.3 0.011 16.0 0.3 3.0 2 1 0 3 3 2 0 Arginine/serine-rich protein PNISR DUF2722 PF10846.8 CDJ70067.1 - 0.013 14.5 39.4 0.11 11.4 15.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF1645 PF07816.11 CDJ70067.1 - 0.019 15.6 9.4 0.019 15.6 9.4 3.8 3 1 0 3 3 2 0 Protein of unknown function (DUF1645) EPL1 PF10513.9 CDJ70067.1 - 0.029 14.8 11.8 0.12 12.7 1.0 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like MAGE PF01454.19 CDJ70067.1 - 0.046 13.4 6.8 0.24 11.1 0.2 2.3 2 0 0 2 2 2 0 MAGE family ASD2 PF08687.11 CDJ70067.1 - 0.072 12.6 14.1 0.31 10.6 6.4 2.3 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 CCSAP PF15748.5 CDJ70067.1 - 0.089 13.0 23.9 0.9 9.7 3.4 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Tim54 PF11711.8 CDJ70067.1 - 0.11 11.2 5.3 1.4 7.7 0.5 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 MecA PF05389.12 CDJ70067.1 - 0.15 11.7 5.5 1.4 8.5 0.2 2.5 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF572 PF04502.13 CDJ70067.1 - 0.33 10.5 16.2 2.3 7.7 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Peptidase_S49_N PF08496.10 CDJ70067.1 - 0.51 10.4 7.5 3.5 7.7 0.8 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.12 CDJ70067.1 - 0.6 9.0 17.1 1.8 7.4 3.7 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Plasmodium_Vir PF05795.11 CDJ70067.1 - 0.61 9.4 13.2 0.074 12.5 6.4 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein RAB3GAP2_N PF14655.6 CDJ70067.1 - 0.74 9.0 18.2 0.018 14.3 3.1 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Presenilin PF01080.17 CDJ70067.1 - 0.81 8.4 20.4 1.8 7.2 1.6 2.3 2 0 0 2 2 2 0 Presenilin PA26 PF04636.13 CDJ70067.1 - 1.3 7.9 5.5 7.9 5.3 0.3 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) SRP-alpha_N PF04086.13 CDJ70067.1 - 1.3 8.9 15.6 1.3 8.8 8.0 2.5 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Pet20 PF08692.10 CDJ70067.1 - 1.4 9.7 5.2 19 6.0 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Suf PF05843.14 CDJ70067.1 - 1.4 8.9 22.5 1.7 8.5 7.2 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) MPM1 PF17234.2 CDJ70067.1 - 1.4 9.1 20.0 1.9 8.7 7.3 2.4 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF2464 PF10240.9 CDJ70067.1 - 1.6 8.2 8.8 5.6 6.5 3.8 2.4 2 0 0 2 2 2 0 Multivesicular body subunit 12 SLC12 PF03522.15 CDJ70067.1 - 2.1 7.3 13.7 5.6 5.9 6.5 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Thg1C PF14413.6 CDJ70067.1 - 2.5 8.3 7.4 3.6 7.7 1.1 2.4 2 0 0 2 2 2 0 Thg1 C terminal domain AUX_IAA PF02309.16 CDJ70067.1 - 3.5 7.4 9.9 16 5.3 0.2 2.3 2 0 0 2 2 2 0 AUX/IAA family DUF4770 PF15994.5 CDJ70067.1 - 4.5 7.5 17.3 8 6.7 4.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) RR_TM4-6 PF06459.12 CDJ70067.1 - 7.8 6.2 14.4 10 5.8 1.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM150 PF15129.6 CDJ70067.1 - 8 6.6 13.1 8.5 6.5 2.4 2.5 2 0 0 2 2 2 0 FAM150 family CLN3 PF02487.17 CDJ70067.1 - 9 5.2 10.8 8.4 5.3 3.8 2.4 2 0 0 2 2 2 0 CLN3 protein ANAPC_CDC26 PF10471.9 CDJ70067.1 - 9.2 7.2 52.2 0.44 11.4 14.3 3.5 4 0 0 4 4 2 0 Anaphase-promoting complex APC subunit CDC26 Activator_LAG-3 PF11498.8 CDJ70068.1 - 4.8 6.0 39.1 0.0069 15.4 14.6 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 IMUP PF15761.5 CDJ70069.1 - 0.00089 19.9 6.8 0.00098 19.8 6.8 1.1 1 0 0 1 1 1 1 Immortalisation up-regulated protein DUF3446 PF11928.8 CDJ70069.1 - 0.0068 16.7 4.0 0.0075 16.5 4.0 1.2 1 0 0 1 1 1 1 Early growth response N-terminal domain SR-25 PF10500.9 CDJ70069.1 - 0.011 15.3 7.2 0.011 15.3 7.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 CDJ70069.1 - 0.14 10.6 3.1 0.13 10.7 3.1 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF755 PF05501.11 CDJ70069.1 - 2.2 8.5 13.3 2.9 8.2 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ70070.1 - 7.5e-05 22.4 8.0 7.5e-05 22.4 8.0 5.9 6 0 0 6 6 6 3 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ70070.1 - 0.00015 21.7 5.3 0.00015 21.7 5.3 10.5 7 2 0 7 7 7 2 Unstructured region C-term to UIM in Ataxin3 CDK2AP PF09806.9 CDJ70070.1 - 0.0066 16.5 5.8 0.0066 16.5 5.8 8.5 5 1 2 7 7 7 2 Cyclin-dependent kinase 2-associated protein Caldesmon PF02029.15 CDJ70070.1 - 2.9 6.6 49.4 0.064 12.0 28.8 4.1 4 0 0 4 4 4 0 Caldesmon Abhydrolase_6 PF12697.7 CDJ70071.1 - 5.7e-16 59.8 2.5 5.7e-16 59.8 2.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ70071.1 - 4e-10 39.8 0.4 1e-07 31.9 0.3 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ70071.1 - 1.6e-06 27.6 0.0 8.6e-06 25.2 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CDJ70071.1 - 7.3e-05 23.0 0.3 0.00012 22.3 0.3 1.3 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 CDJ70071.1 - 0.00015 20.6 0.3 0.28 9.9 0.0 2.1 2 0 0 2 2 2 2 Ndr family PGAP1 PF07819.13 CDJ70071.1 - 0.021 14.6 0.1 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein DUF3446 PF11928.8 CDJ70071.1 - 0.029 14.7 3.9 0.029 14.7 3.9 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain Lipase_3 PF01764.25 CDJ70071.1 - 0.033 14.1 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 CDJ70071.1 - 0.053 12.4 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme SR-25 PF10500.9 CDJ70071.1 - 2.2 7.8 9.7 3.3 7.3 9.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ70072.1 - 0.027 14.1 68.8 0.029 14.0 0.3 3.5 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein SDA1 PF05285.12 CDJ70072.1 - 0.51 9.7 26.6 0.76 9.1 26.6 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CDJ70072.1 - 3.1 6.0 26.1 5.5 5.2 26.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.13 CDJ70072.1 - 4.5 5.7 30.9 6.4 5.2 30.9 1.1 1 0 0 1 1 1 0 Utp14 protein SOG2 PF10428.9 CDJ70072.1 - 5 6.2 37.5 6.4 5.9 37.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TPK_catalytic PF04263.16 CDJ70073.1 - 9.2e-07 28.9 0.0 1.7e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TFIIA PF03153.13 CDJ70073.1 - 0.04 13.9 9.5 0.057 13.4 9.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IMUP PF15761.5 CDJ70073.1 - 0.17 12.6 9.7 0.59 10.9 9.7 1.9 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ70073.1 - 0.72 9.4 12.8 0.16 11.6 8.9 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ketoacyl-synt_2 PF13723.6 CDJ70073.1 - 1 8.9 14.2 0.43 10.2 11.6 1.7 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ANAPC_CDC26 PF10471.9 CDJ70073.1 - 1.8 9.5 13.6 4.6 8.2 9.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DivIC PF04977.15 CDJ70073.1 - 6.9 6.5 8.7 13 5.6 8.7 1.4 1 0 0 1 1 1 0 Septum formation initiator IPPT PF01715.17 CDJ70074.1 - 4.7e-24 85.5 0.0 6.9e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 IPP transferase PhoH PF02562.16 CDJ70074.1 - 0.0012 18.3 0.1 0.0018 17.8 0.1 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.6 CDJ70074.1 - 0.0019 18.6 1.3 0.0041 17.5 1.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 CDJ70074.1 - 0.0032 17.5 0.3 0.0092 16.0 0.1 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 CDJ70074.1 - 0.0048 16.6 0.0 0.008 15.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CDJ70074.1 - 0.0071 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 CDJ70074.1 - 0.0087 16.2 0.0 0.023 14.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ70074.1 - 0.015 15.6 0.1 0.035 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 CDJ70074.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase IPT PF01745.16 CDJ70074.1 - 0.023 14.1 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase NACHT PF05729.12 CDJ70074.1 - 0.036 14.0 0.3 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 CDJ70074.1 - 0.04 12.9 0.0 0.078 11.9 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CDJ70074.1 - 0.045 13.6 0.1 0.087 12.7 0.0 1.5 2 0 0 2 2 1 0 RsgA GTPase Zeta_toxin PF06414.12 CDJ70074.1 - 0.048 12.9 0.1 0.078 12.2 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin ParA PF10609.9 CDJ70074.1 - 0.06 12.8 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase NTPase_1 PF03266.15 CDJ70074.1 - 0.062 13.2 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 CDJ70074.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 CDJ70074.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 CDJ70074.1 - 0.086 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SR-25 PF10500.9 CDJ70074.1 - 0.15 11.6 20.2 0.25 10.9 20.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NODP PF07684.12 CDJ70074.1 - 0.16 12.1 0.1 0.16 12.1 0.1 2.5 2 0 0 2 2 2 0 NOTCH protein AAA_7 PF12775.7 CDJ70074.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_PrkA PF08298.11 CDJ70074.1 - 0.18 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Conotoxin PF02950.17 CDJ70074.1 - 4.2 8.5 10.0 0.12 13.4 2.6 2.3 2 0 0 2 2 1 0 Conotoxin Pex14_N PF04695.13 CDJ70074.1 - 6.2 7.5 12.4 2 9.0 4.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC117 PF15810.5 CDJ70074.1 - 8.3 6.7 8.9 0.19 12.0 1.7 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 117 Spt20 PF12090.8 CDJ70076.1 - 0.015 14.9 5.3 0.015 14.9 5.3 2.9 2 1 0 2 2 2 0 Spt20 family G0-G1_switch_2 PF15103.6 CDJ70076.1 - 0.074 13.5 1.2 0.074 13.5 1.2 2.8 3 0 0 3 3 3 0 G0/G1 switch protein 2 DUF1840 PF08895.11 CDJ70076.1 - 0.29 11.5 15.5 0.2 12.0 9.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) Ndc1_Nup PF09531.10 CDJ70076.1 - 0.57 8.8 12.8 0.78 8.3 12.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EOS1 PF12326.8 CDJ70076.1 - 1.2 9.0 4.4 3.1 7.7 4.4 1.8 1 1 0 1 1 1 0 N-glycosylation protein DUF3801 PF12687.7 CDJ70076.1 - 1.4 8.9 13.0 5.6 7.0 8.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) AIF_C PF14721.6 CDJ70076.1 - 2.5 8.5 8.6 0.34 11.3 1.6 2.3 2 1 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Orf78 PF06024.12 CDJ70076.1 - 4.9 7.5 7.6 2.2 8.6 2.4 2.4 2 1 0 2 2 2 0 Orf78 (ac78) zf-C3HC4_3 PF13920.6 CDJ70077.1 - 3.5e-08 33.2 8.8 3.5e-08 33.2 8.8 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ70077.1 - 1.2e-06 28.3 8.4 1.2e-06 28.3 8.4 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ70077.1 - 1.6e-06 27.8 10.4 6.9e-06 25.8 10.4 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ70077.1 - 2e-05 24.8 10.1 2e-05 24.8 10.1 3.6 4 0 0 4 4 3 1 Ring finger domain Prok-RING_4 PF14447.6 CDJ70077.1 - 5.3e-05 23.0 9.6 5.3e-05 23.0 9.6 2.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDJ70077.1 - 0.0023 17.8 8.9 0.0023 17.8 8.9 3.8 3 1 1 4 4 2 1 zinc-RING finger domain DUF3682 PF12446.8 CDJ70077.1 - 0.011 16.2 23.1 0.011 16.2 23.1 8.2 6 2 2 8 8 2 0 Protein of unknown function (DUF3682) DUF966 PF06136.13 CDJ70077.1 - 0.36 10.5 29.4 0.14 11.9 10.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF966) DUF1645 PF07816.11 CDJ70077.1 - 1.6 9.3 38.6 0.21 12.1 18.8 4.3 4 2 0 4 4 4 0 Protein of unknown function (DUF1645) DUF572 PF04502.13 CDJ70077.1 - 1.8 8.1 30.5 0.32 10.6 12.7 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) Utp14 PF04615.13 CDJ70077.1 - 2.1 6.8 36.1 0.087 11.4 13.8 2.4 2 0 0 2 2 2 0 Utp14 protein zf-RING_UBOX PF13445.6 CDJ70077.1 - 7 6.8 22.2 0.033 14.2 10.3 3.1 2 0 0 2 2 2 0 RING-type zinc-finger PIP5K PF01504.18 CDJ70078.1 - 0.00035 19.9 3.2 0.00047 19.5 3.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2722 PF10846.8 CDJ70078.1 - 0.0004 19.4 10.3 0.0004 19.4 10.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) NAD_binding_9 PF13454.6 CDJ70078.1 - 0.0035 17.3 1.9 0.011 15.7 0.2 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Endostatin PF06482.11 CDJ70078.1 - 0.0063 16.0 7.0 0.0091 15.5 7.0 1.2 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin MecA PF05389.12 CDJ70078.1 - 0.019 14.6 5.4 0.73 9.4 0.1 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Methyltransf_34 PF11312.8 CDJ70078.1 - 0.026 13.8 0.7 0.047 12.9 0.7 1.4 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase FAD_binding_3 PF01494.19 CDJ70078.1 - 0.033 13.5 0.1 0.033 13.5 0.1 1.8 2 0 0 2 2 1 0 FAD binding domain NAD_binding_8 PF13450.6 CDJ70078.1 - 0.05 13.8 0.1 0.05 13.8 0.1 2.6 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Otopetrin PF03189.13 CDJ70078.1 - 0.054 12.3 0.1 0.062 12.1 0.1 1.1 1 0 0 1 1 1 0 Otopetrin Pyr_redox_2 PF07992.14 CDJ70078.1 - 0.063 12.5 1.1 0.076 12.2 0.5 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Topoisom_I_N PF02919.15 CDJ70078.1 - 0.069 12.6 3.8 0.81 9.1 0.4 2.1 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment PAT1 PF09770.9 CDJ70078.1 - 0.074 11.3 21.1 0.097 10.9 21.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gti1_Pac2 PF09729.9 CDJ70078.1 - 0.084 13.0 5.4 0.12 12.4 5.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Neur_chan_memb PF02932.16 CDJ70078.1 - 0.13 12.3 6.4 0.26 11.3 6.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MAM33 PF02330.16 CDJ70078.1 - 0.13 12.2 9.1 1.1 9.2 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial glycoprotein Presenilin PF01080.17 CDJ70078.1 - 0.15 10.8 14.1 0.29 9.9 14.1 1.4 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ70078.1 - 0.15 11.0 8.3 0.22 10.5 8.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF1800 PF08811.11 CDJ70078.1 - 0.16 11.0 9.6 0.22 10.5 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) CLN3 PF02487.17 CDJ70078.1 - 0.16 11.0 4.9 0.29 10.1 4.9 1.3 1 0 0 1 1 1 0 CLN3 protein Tau95_N PF17682.1 CDJ70078.1 - 0.18 12.0 7.9 1.2 9.3 0.7 2.1 2 0 0 2 2 2 0 Tau95 Triple barrel domain Rxt3 PF08642.10 CDJ70078.1 - 0.18 12.6 6.7 2.7 8.8 0.3 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Thi4 PF01946.17 CDJ70078.1 - 0.18 11.0 0.0 0.38 10.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DUF4050 PF13259.6 CDJ70078.1 - 0.19 12.0 7.8 0.31 11.4 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF4770 PF15994.5 CDJ70078.1 - 0.21 11.8 13.6 1.3 9.3 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) MPM1 PF17234.2 CDJ70078.1 - 0.25 11.6 12.3 2.3 8.4 4.1 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF4366 PF14283.6 CDJ70078.1 - 0.27 11.3 4.3 1.7 8.7 4.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) RR_TM4-6 PF06459.12 CDJ70078.1 - 0.28 11.0 9.0 0.47 10.2 9.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rbc25 PF08292.12 CDJ70078.1 - 0.32 11.2 10.0 0.96 9.7 1.8 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Lin-8 PF03353.15 CDJ70078.1 - 0.4 10.2 12.6 0.54 9.8 12.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SpoIIP PF07454.11 CDJ70078.1 - 0.44 10.0 11.6 1 8.7 1.2 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2828 PF11443.8 CDJ70078.1 - 0.48 8.5 9.4 0.64 8.0 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Peptidase_S46 PF10459.9 CDJ70078.1 - 0.55 8.8 7.5 0.72 8.4 7.5 1.1 1 0 0 1 1 1 0 Peptidase S46 Glyco_hydro_9 PF00759.19 CDJ70078.1 - 0.73 9.2 4.7 3.7 6.9 4.7 2.0 1 1 0 1 1 1 0 Glycosyl hydrolase family 9 Orf78 PF06024.12 CDJ70078.1 - 0.76 10.1 9.0 1.7 9.0 0.8 2.5 2 0 0 2 2 2 0 Orf78 (ac78) Peroxin-13_N PF04088.13 CDJ70078.1 - 0.93 9.8 6.5 8.8 6.6 1.2 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Peptidase_S49_N PF08496.10 CDJ70078.1 - 1 9.4 10.2 4.4 7.3 0.3 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MDM10 PF12519.8 CDJ70078.1 - 1.4 7.7 5.4 2 7.2 5.4 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Het-C PF07217.11 CDJ70078.1 - 1.4 7.4 6.1 2.2 6.7 6.1 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C AUX_IAA PF02309.16 CDJ70078.1 - 1.5 8.6 7.3 2.3 8.0 7.3 1.2 1 0 0 1 1 1 0 AUX/IAA family Rpp20 PF12328.8 CDJ70078.1 - 1.6 8.7 12.7 2.2 8.2 0.9 2.1 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Fes1 PF08609.10 CDJ70078.1 - 2 9.4 6.9 5.3 8.0 0.4 2.5 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Folliculin PF11704.8 CDJ70078.1 - 3.2 7.6 8.2 5.1 6.9 8.2 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport BRF1 PF07741.13 CDJ70078.1 - 3.8 7.9 10.7 11 6.4 0.6 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF1980 PF09323.10 CDJ70078.1 - 6 6.8 7.8 8.2 6.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) ALMT PF11744.8 CDJ70078.1 - 6 5.6 8.8 8.6 5.1 8.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SARAF PF06682.12 CDJ70078.1 - 6.1 6.4 15.7 9.3 5.8 15.7 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis RLL PF10036.9 CDJ70078.1 - 6.9 6.4 16.4 1.5 8.6 1.2 2.3 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein AIF_C PF14721.6 CDJ70078.1 - 8.6 6.7 10.5 8.7 6.7 1.7 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF533 PF04391.12 CDJ70078.1 - 8.9 5.9 20.0 0.85 9.2 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Cyt_bd_oxida_II PF02322.15 CDJ70079.1 - 0.087 12.2 6.5 4.5 6.5 3.9 2.1 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II TMEM51 PF15345.6 CDJ70079.1 - 0.64 9.8 3.5 0.17 11.7 0.2 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 Sin_N PF04801.13 CDJ70080.1 - 0.17 11.1 13.9 0.26 10.4 13.9 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region Lin-8 PF03353.15 CDJ70080.1 - 0.17 11.4 12.0 0.23 11.0 12.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist EPL1 PF10513.9 CDJ70080.1 - 0.17 12.2 6.3 0.28 11.6 6.3 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Peptidase_S64 PF08192.11 CDJ70080.1 - 0.83 8.1 5.7 1 7.8 5.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Bud13 PF09736.9 CDJ70080.1 - 1.4 9.3 14.2 2.5 8.5 14.2 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Presenilin PF01080.17 CDJ70080.1 - 1.7 7.4 10.6 3.2 6.4 10.6 1.5 1 0 0 1 1 1 0 Presenilin MMR1 PF08505.10 CDJ70080.1 - 3.6 7.8 12.6 5.9 7.1 12.6 1.5 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SpoIIP PF07454.11 CDJ70080.1 - 5.3 6.4 10.3 7.4 5.9 10.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4481 PF14800.6 CDJ70080.1 - 7.5 5.9 7.7 11 5.4 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) Baculo_PP31 PF05311.11 CDJ70080.1 - 8.6 5.8 12.4 13 5.1 12.4 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) zf-CDGSH PF09360.10 CDJ70081.1 - 5.2e-11 42.6 0.2 1.4e-10 41.2 0.1 1.7 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type DUF2076 PF09849.9 CDJ70081.1 - 8.6e-05 22.7 2.3 0.00012 22.3 2.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) SARAF PF06682.12 CDJ70081.1 - 0.015 15.0 0.5 0.018 14.7 0.5 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2309 PF10070.9 CDJ70081.1 - 0.016 13.5 0.3 0.02 13.3 0.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Phage_H_T_join PF05521.11 CDJ70081.1 - 0.054 14.0 1.1 0.071 13.6 0.4 1.5 2 0 0 2 2 2 0 Phage head-tail joining protein DUF3180 PF11377.8 CDJ70081.1 - 0.083 13.0 1.5 0.11 12.6 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) Trep_Strep PF09605.10 CDJ70081.1 - 0.09 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) TMEM237 PF15383.6 CDJ70081.1 - 0.12 11.5 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 FxsA PF04186.13 CDJ70081.1 - 4 7.6 5.3 1.7 8.8 0.2 2.2 1 1 1 2 2 2 0 FxsA cytoplasmic membrane protein EF-hand_4 PF12763.7 CDJ70082.1 - 1.1e-13 51.0 0.0 1.9e-05 24.5 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CDJ70082.1 - 0.0058 16.1 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CDJ70082.1 - 0.09 12.8 0.0 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain RSRP PF17069.5 CDJ70082.1 - 1.2 8.7 37.4 0.16 11.5 14.0 2.8 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 CAP PF00188.26 CDJ70083.1 - 0.0024 18.7 0.0 0.0035 18.2 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ70084.1 - 0.034 15.0 0.2 0.049 14.5 0.2 1.5 1 1 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ70085.1 - 0.0056 17.5 0.3 0.0078 17.0 0.3 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ70086.1 - 0.00028 21.7 0.1 0.0004 21.2 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ70087.1 - 2.1e-05 25.4 1.8 0.093 13.6 0.1 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family CAP PF00188.26 CDJ70089.1 - 0.0051 17.6 0.1 0.0082 17.0 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDJ70090.1 - 0.028 15.3 0.8 0.037 14.9 0.8 1.4 1 1 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ70091.1 - 0.02 15.7 0.2 0.037 14.9 0.2 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family DsbB PF02600.16 CDJ70092.1 - 0.36 11.3 5.0 5.4 7.4 0.4 2.5 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB Clathrin PF00637.20 CDJ70093.1 - 1.5e-07 31.4 3.1 6.2e-06 26.1 0.2 3.0 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CDJ70093.1 - 2.8e-05 24.5 0.0 2.8e-05 24.5 0.0 5.1 7 0 0 7 7 7 1 Vacuolar sorting protein 39 domain 2 DUF2722 PF10846.8 CDJ70093.1 - 0.0011 18.0 5.7 0.0011 18.0 5.7 4.3 3 1 1 4 4 4 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ70093.1 - 0.003 17.2 13.2 0.003 17.2 13.2 4.9 3 1 1 4 4 4 2 Spt20 family Isy1 PF06246.12 CDJ70093.1 - 0.025 14.2 22.3 0.085 12.4 6.0 3.3 3 0 0 3 3 3 0 Isy1-like splicing family RskA PF10099.9 CDJ70093.1 - 0.028 14.7 0.4 0.028 14.7 0.4 7.2 4 3 2 6 6 6 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ70093.1 - 1.4 7.6 27.8 0.52 9.0 11.0 2.8 3 0 0 3 3 3 0 Presenilin Orf78 PF06024.12 CDJ70093.1 - 1.8 8.9 18.6 1.2 9.5 1.0 4.4 4 0 0 4 4 4 0 Orf78 (ac78) ATXN-1_C PF12547.8 CDJ70094.1 - 0.048 14.0 4.7 0.057 13.8 2.3 2.4 1 1 1 2 2 2 0 Capicua transcriptional repressor modulator Dehydrin PF00257.19 CDJ70094.1 - 9 6.8 18.7 4.4 7.8 13.1 2.6 2 1 0 2 2 2 0 Dehydrin EF-hand_1 PF00036.32 CDJ70095.1 - 6.3e-16 56.7 0.1 4.6e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ70095.1 - 1.4e-13 49.5 0.1 3.4e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CDJ70095.1 - 8e-11 42.2 0.0 9.6e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CDJ70095.1 - 1.4e-09 37.7 0.2 0.00011 21.9 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ70095.1 - 5.3e-08 32.0 0.1 1.1e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 CDJ70095.1 - 0.0033 17.7 0.0 0.004 17.5 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain Cript PF10235.9 CDJ70096.1 - 4e-14 53.0 5.7 4e-14 53.0 5.7 1.7 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 CDJ70096.1 - 0.006 16.6 5.5 0.034 14.2 2.4 2.4 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 CDJ70096.1 - 0.042 14.6 7.4 0.073 13.8 4.2 2.4 2 1 0 2 2 2 0 zinc-ribbon family zf-FCS PF06467.14 CDJ70096.1 - 0.96 9.4 0.1 0.96 9.4 0.1 2.9 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif C1_1 PF00130.22 CDJ70096.1 - 1.1 9.2 10.5 5.4 7.0 8.5 2.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DiS_P_DiS PF06750.13 CDJ70096.1 - 1.3 9.2 8.7 0.64 10.2 4.3 2.4 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Sar8_2 PF03058.14 CDJ70096.1 - 2.4 8.7 11.1 1.3 9.6 7.2 2.1 1 1 1 2 2 2 0 Sar8.2 family Kelch_1 PF01344.25 CDJ70097.1 - 1.5e-48 162.1 4.5 6.3e-10 38.5 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CDJ70097.1 - 1.7e-36 122.9 18.9 1.7e-07 30.9 0.1 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 CDJ70097.1 - 3.1e-36 122.5 10.8 2.4e-06 27.6 0.0 6.5 2 2 4 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CDJ70097.1 - 5.6e-35 119.0 19.6 5.2e-06 26.6 0.0 8.9 9 0 0 9 9 9 6 Galactose oxidase, central domain Kelch_4 PF13418.6 CDJ70097.1 - 2.9e-31 107.2 12.0 1.7e-06 27.9 0.1 6.6 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ70097.1 - 3e-28 97.3 4.6 8.5e-06 25.6 0.0 6.9 7 0 0 7 7 7 6 Kelch motif BTB PF00651.31 CDJ70097.1 - 1.8e-14 53.9 0.0 1.4e-13 51.0 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain SR-25 PF10500.9 CDJ70097.1 - 0.0015 18.2 17.1 0.0015 18.2 17.1 5.1 3 2 2 5 5 5 1 Nuclear RNA-splicing-associated protein V_ATPase_I PF01496.19 CDJ70099.1 - 6.6e-71 239.4 0.0 7.7e-39 133.3 0.0 3.3 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family Spore_III_AB PF09548.10 CDJ70099.1 - 0.0021 18.2 0.6 0.013 15.7 0.2 2.5 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) SOBP PF15279.6 CDJ70099.1 - 4.5 7.8 9.0 0.55 10.8 3.7 1.9 2 0 0 2 2 2 0 Sine oculis-binding protein Proteasome PF00227.26 CDJ70100.1 - 5.9e-45 153.1 0.0 7.6e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ70100.1 - 2.8e-11 42.9 0.0 7.1e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ORF6C PF10552.9 CDJ70101.1 - 0.037 14.1 4.2 0.065 13.3 4.2 1.4 1 0 0 1 1 1 0 ORF6C domain betaPIX_CC PF16523.5 CDJ70101.1 - 0.069 13.0 8.5 0.13 12.1 8.5 1.4 1 0 0 1 1 1 0 betaPIX coiled coil TMPIT PF07851.13 CDJ70101.1 - 1 8.5 3.4 1.4 8.1 3.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein APG6_N PF17675.1 CDJ70101.1 - 1.6 9.3 11.2 1.9 9.0 11.2 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DASH_Spc19 PF08287.11 CDJ70101.1 - 2.5 8.0 14.2 1.4 8.8 7.0 2.0 2 0 0 2 2 2 0 Spc19 CENP-H PF05837.12 CDJ70101.1 - 2.7 8.4 10.1 0.11 12.9 3.7 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.15 CDJ70101.1 - 4 7.3 9.5 15 5.4 6.2 2.4 1 1 1 2 2 2 0 Septum formation initiator FmdE PF02663.14 CDJ70101.1 - 4 7.5 7.0 3.6 7.6 5.9 1.4 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Ribosomal_L34 PF00468.17 CDJ70101.1 - 7.3 6.7 12.9 1.3 9.1 3.4 2.3 2 0 0 2 2 2 0 Ribosomal protein L34 DHC_N1 PF08385.12 CDJ70102.1 - 2.5e-26 92.4 0.2 1.8e-23 83.1 0.3 2.1 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 DHC_N1 PF08385.12 CDJ70103.1 - 6.2e-61 206.7 0.0 1.1e-38 133.2 0.0 2.1 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CDJ70104.1 - 5e-113 378.2 8.5 5e-113 378.2 8.5 3.1 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 CDJ70104.1 - 7.2e-100 334.1 0.4 2.6e-94 315.9 0.0 3.2 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CDJ70104.1 - 3.8e-10 39.9 0.0 1.9e-06 27.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Nab2 PF11517.8 CDJ70104.1 - 0.019 15.2 0.0 0.25 11.7 0.0 2.7 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) MMR_HSR1 PF01926.23 CDJ70104.1 - 0.026 14.6 0.3 0.28 11.3 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ70104.1 - 0.031 14.0 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CDJ70104.1 - 0.033 13.7 0.2 0.15 11.6 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region KTI12 PF08433.10 CDJ70104.1 - 0.056 12.9 0.1 0.27 10.6 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 CDJ70104.1 - 0.057 13.3 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Roc PF08477.13 CDJ70104.1 - 0.059 13.6 2.1 0.31 11.2 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 CDJ70104.1 - 0.078 12.0 0.1 0.21 10.6 0.1 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1611 PF07755.11 CDJ70104.1 - 0.13 11.6 0.1 0.27 10.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain AAA_16 PF13191.6 CDJ70104.1 - 0.14 12.6 0.0 3.2 8.1 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 CDJ70104.1 - 0.15 11.4 0.0 0.38 10.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDJ70104.1 - 0.15 12.5 0.1 2.8 8.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_8 PF12780.7 CDJ70105.1 - 1.3e-87 293.4 0.1 3.2e-87 292.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CDJ70105.1 - 5.9e-51 172.5 0.1 5e-50 169.5 0.0 2.6 2 1 1 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 CDJ70105.1 - 6.3e-34 117.5 20.5 7.8e-33 113.9 20.5 2.3 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 CDJ70105.1 - 2.3e-19 69.5 3.3 1.2e-18 67.1 0.0 3.0 3 0 0 3 3 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CDJ70105.1 - 7.6e-19 68.1 0.1 4e-18 65.7 0.1 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDJ70105.1 - 3.8e-08 33.4 0.0 0.00027 21.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ70105.1 - 0.0018 18.7 2.0 0.3 11.5 0.0 4.0 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) DUF4407 PF14362.6 CDJ70105.1 - 0.16 11.3 19.8 0.096 12.0 6.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UPF0565 PF10561.9 CDJ70105.1 - 0.22 10.7 5.2 0.14 11.3 2.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 V_ATPase_I PF01496.19 CDJ70105.1 - 0.22 9.4 13.7 0.047 11.6 0.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 CDJ70105.1 - 0.65 8.8 25.9 0.51 9.2 2.4 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein PDCD7 PF16021.5 CDJ70105.1 - 0.97 8.5 26.0 0.0085 15.2 10.7 2.2 2 0 0 2 2 2 0 Programmed cell death protein 7 PRKG1_interact PF15898.5 CDJ70105.1 - 2.4 9.1 22.9 2.5 9.1 11.0 2.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain ERM PF00769.19 CDJ70105.1 - 2.4 7.9 28.6 2.1 8.1 11.0 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Tho2 PF11262.8 CDJ70105.1 - 2.5 7.2 11.6 2.5 7.2 5.1 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4200 PF13863.6 CDJ70105.1 - 2.9 8.3 32.1 4 7.8 16.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Mac PF12464.8 CDJ70105.1 - 3.8 7.8 8.4 0.79 10.0 0.2 3.2 2 1 0 2 2 2 0 Maltose acetyltransferase LUC7 PF03194.15 CDJ70105.1 - 4.8 6.8 15.0 0.11 12.2 5.3 2.2 2 0 0 2 2 2 0 LUC7 N_terminus Fez1 PF06818.15 CDJ70105.1 - 7.4 7.0 22.7 2.6 8.4 8.0 2.4 2 0 0 2 2 2 0 Fez1 Laminin_I PF06008.14 CDJ70105.1 - 8.6 6.0 28.2 0.9 9.2 5.0 3.3 2 1 1 3 3 3 0 Laminin Domain I DUF948 PF06103.11 CDJ70105.1 - 8.7 6.7 9.4 29 5.0 2.1 3.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DASH_Duo1 PF08651.10 CDJ70105.1 - 10 6.0 8.4 0.73 9.7 0.9 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 AAA_9 PF12781.7 CDJ70106.1 - 5.8e-52 176.0 0.0 6.8e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 CDJ70107.1 - 3.2e-83 279.5 0.0 8.1e-83 278.2 0.0 1.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CDJ70107.1 - 1.9e-49 167.6 0.0 3.6e-49 166.7 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ70107.1 - 5.4e-36 123.3 0.0 2.6e-35 121.1 0.0 2.3 1 1 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_9 PF12781.7 CDJ70107.1 - 8.4e-11 41.4 7.1 1.5e-10 40.6 7.1 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region DUF4795 PF16043.5 CDJ70107.1 - 2.7 7.5 7.6 6.1 6.4 6.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Spore_III_AB PF09548.10 CDJ70107.1 - 7.9 6.6 7.2 19 5.3 5.4 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Surface_antigen PF11054.8 CDJ70108.1 - 1.4e-32 113.3 0.5 1.7e-32 113.0 0.5 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ70109.1 - 1.3e-41 142.9 6.1 3.2e-31 108.9 3.6 2.2 2 0 0 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ70110.1 - 5.3e-31 108.1 0.6 9.3e-31 107.4 0.6 1.4 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen LEH PF07858.12 CDJ70110.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Surface_antigen PF11054.8 CDJ70111.1 - 3.5e-28 98.9 1.1 2.1e-27 96.3 1.1 1.8 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Tom7 PF08038.12 CDJ70111.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 TOM7 family Surface_antigen PF11054.8 CDJ70112.1 - 2.3e-27 96.2 0.8 3.4e-27 95.7 0.8 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen AlaDh_PNT_N PF05222.15 CDJ70113.1 - 4.3e-37 127.4 0.1 5.7e-37 127.0 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain WBP-1 PF11669.8 CDJ70113.1 - 0.0046 17.6 0.3 0.0046 17.6 0.3 1.8 2 0 0 2 2 2 1 WW domain-binding protein 1 DUF4381 PF14316.6 CDJ70113.1 - 0.018 15.3 1.0 0.028 14.6 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FAM176 PF14851.6 CDJ70113.1 - 0.19 11.4 0.1 0.33 10.6 0.1 1.3 1 0 0 1 1 1 0 FAM176 family EphA2_TM PF14575.6 CDJ70113.1 - 0.21 12.5 0.2 0.68 10.9 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RRM_1 PF00076.22 CDJ70116.1 - 3.4e-22 78.0 0.1 1.3e-08 34.5 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ70116.1 - 0.00034 20.4 0.0 9.2 6.2 0.0 3.7 3 0 0 3 3 3 3 Occluded RNA-recognition motif BRAP2 PF07576.12 CDJ70116.1 - 0.051 13.8 0.0 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 BRCA1-associated protein 2 Aa_trans PF01490.18 CDJ70117.1 - 1.4e-06 27.3 5.5 1.4e-06 27.3 5.5 2.1 3 0 0 3 3 3 1 Transmembrane amino acid transporter protein SPX PF03105.19 CDJ70117.1 - 1 9.2 23.1 0.075 12.9 16.2 2.1 2 0 0 2 2 2 0 SPX domain Hid1 PF12722.7 CDJ70117.1 - 1.6 6.8 4.8 2.2 6.3 4.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.13 CDJ70117.1 - 3.9 7.4 11.2 6.6 6.6 11.2 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M24 PF00557.24 CDJ70118.1 - 2.7e-31 108.9 0.7 3.1e-31 108.7 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 CDK2AP PF09806.9 CDJ70118.1 - 0.15 12.1 5.0 22 5.0 7.7 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein RskA PF10099.9 CDJ70118.1 - 0.43 10.9 8.7 0.76 10.0 8.7 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Cnd2 PF05786.14 CDJ70118.1 - 4.5 5.8 5.5 6.5 5.3 5.5 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Med3 PF11593.8 CDJ70118.1 - 7.5 5.6 9.7 11 5.1 9.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 CDJ70120.1 - 0.014 15.1 17.6 0.014 15.1 17.6 1.7 2 0 0 2 2 2 0 Spt20 family YhfC PF10086.9 CDJ70120.1 - 0.24 10.7 1.7 0.45 9.8 1.7 1.4 1 0 0 1 1 1 0 YhfC intramembrane metalloprotease SpoIIP PF07454.11 CDJ70120.1 - 0.48 9.8 4.2 0.29 10.5 1.0 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Conotoxin PF02950.17 CDJ70120.1 - 0.97 10.5 6.0 3.6 8.7 6.0 2.0 1 0 0 1 1 1 0 Conotoxin Ashwin PF15323.6 CDJ70120.1 - 0.99 9.4 17.5 5.6 6.9 17.5 2.1 1 1 0 1 1 1 0 Developmental protein Roughex PF06020.11 CDJ70120.1 - 1.8 7.6 8.1 2.9 6.9 8.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein EIIBC-GUT_N PF03612.14 CDJ70120.1 - 3.1 7.5 6.0 0.41 10.4 1.5 1.8 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Plasmodium_Vir PF05795.11 CDJ70120.1 - 5.3 6.4 7.4 0.24 10.8 1.5 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein FAM199X PF15814.5 CDJ70121.1 - 0.075 12.1 15.6 0.096 11.7 15.6 1.0 1 0 0 1 1 1 0 Protein family FAM199X FSA_C PF10479.9 CDJ70121.1 - 1.1 7.4 5.3 1.2 7.2 5.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TFIIA PF03153.13 CDJ70121.1 - 1.3 8.9 26.5 1.6 8.7 26.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DSBA PF01323.20 CDJ70121.1 - 6.2 6.5 12.9 8.9 6.0 12.9 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Tic110 PF16940.5 CDJ70121.1 - 9.8 4.5 18.3 12 4.3 18.3 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Vps52 PF04129.12 CDJ70122.1 - 1.4e-13 50.5 0.6 1.9e-13 50.0 0.6 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family SUIM_assoc PF16619.5 CDJ70122.1 - 0.0073 16.4 4.3 0.0073 16.4 4.3 2.1 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Lin-8 PF03353.15 CDJ70122.1 - 0.21 11.1 10.3 0.32 10.5 10.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SRP-alpha_N PF04086.13 CDJ70122.1 - 0.28 11.1 14.4 0.4 10.6 14.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1117 PF06547.12 CDJ70122.1 - 0.29 11.7 8.7 0.16 12.5 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) TFIIA PF03153.13 CDJ70122.1 - 0.85 9.5 22.8 1.2 9.1 22.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RIFIN PF02009.16 CDJ70122.1 - 1.3 8.8 7.5 1.9 8.3 7.5 1.2 1 0 0 1 1 1 0 Rifin Spt20 PF12090.8 CDJ70122.1 - 2.6 7.6 20.0 0.039 13.6 12.7 1.6 2 0 0 2 2 2 0 Spt20 family BAF1_ABF1 PF04684.13 CDJ70122.1 - 2.8 6.9 12.3 3.6 6.5 12.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SAPS PF04499.15 CDJ70122.1 - 4.2 6.0 5.5 5.7 5.6 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SPX PF03105.19 CDJ70122.1 - 4.4 7.1 14.8 7.4 6.4 14.8 1.2 1 0 0 1 1 1 0 SPX domain DUF572 PF04502.13 CDJ70122.1 - 4.8 6.7 8.9 6.9 6.2 8.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF966 PF06136.13 CDJ70122.1 - 6.8 6.3 12.4 9.5 5.8 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SR-25 PF10500.9 CDJ70123.1 - 0.0038 16.9 10.8 0.0039 16.8 10.0 1.5 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein RIFIN PF02009.16 CDJ70123.1 - 4.8 7.0 15.2 5.6 6.8 15.2 1.1 1 0 0 1 1 1 0 Rifin PP2C PF00481.21 CDJ70125.1 - 2.6e-30 105.9 0.1 2.2e-19 70.1 0.0 4.1 3 1 1 4 4 4 3 Protein phosphatase 2C Apt1 PF10351.9 CDJ70125.1 - 0.081 11.8 22.5 1 8.2 7.7 3.1 3 0 0 3 3 3 0 Golgi-body localisation protein domain TFIIA PF03153.13 CDJ70125.1 - 0.28 11.1 28.5 1.3 8.9 8.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CDJ70125.1 - 7.4 3.6 24.6 0.025 11.7 0.7 3.0 3 0 0 3 3 3 0 Gene regulated by oestrogen in breast cancer Cation_efflux PF01545.21 CDJ70126.1 - 0.0022 17.7 7.1 1.1 8.9 4.9 3.6 3 1 0 3 3 3 1 Cation efflux family IncE PF17627.2 CDJ70126.1 - 0.0071 16.4 0.0 0.0071 16.4 0.0 2.5 2 1 0 2 2 2 1 Inclusion membrane protein E SUR7 PF06687.12 CDJ70126.1 - 0.042 13.5 11.0 0.47 10.0 0.0 2.6 2 1 0 2 2 2 0 SUR7/PalI family Amastin PF07344.11 CDJ70126.1 - 0.08 12.8 0.1 0.08 12.8 0.1 3.1 2 1 0 2 2 2 0 Amastin surface glycoprotein NEMP PF10225.9 CDJ70126.1 - 0.2 11.3 5.0 0.62 9.7 0.3 2.5 2 0 0 2 2 2 0 NEMP family 7tm_1 PF00001.21 CDJ70126.1 - 0.46 9.7 2.0 11 5.2 0.5 2.2 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) SCAMP PF04144.13 CDJ70126.1 - 0.53 10.6 5.5 0.56 10.5 1.4 2.3 2 0 0 2 2 2 0 SCAMP family Presenilin PF01080.17 CDJ70126.1 - 1.5 7.5 10.1 0.2 10.4 1.7 2.5 2 0 0 2 2 2 0 Presenilin BatD PF13584.6 CDJ70126.1 - 2.7 6.7 11.9 8.1 5.1 0.4 2.9 2 1 0 2 2 2 0 Oxygen tolerance Lin-8 PF03353.15 CDJ70126.1 - 3.9 7.0 11.3 1.5 8.3 4.1 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Collagen PF01391.18 CDJ70127.1 - 2.6e-10 39.9 68.3 1.8e-08 34.0 31.3 6.9 5 1 1 6 6 6 2 Collagen triple helix repeat (20 copies) Spt20 PF12090.8 CDJ70127.1 - 0.08 12.5 11.6 1.4 8.4 4.9 2.3 2 0 0 2 2 2 0 Spt20 family DUF4667 PF15700.5 CDJ70127.1 - 8.9 6.3 11.2 6.1 6.9 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4667) LsmAD PF06741.13 CDJ70128.1 - 9.3e-12 45.3 0.6 9.3e-12 45.3 0.6 4.1 3 1 0 3 3 3 1 LsmAD domain Yae1_N PF09811.9 CDJ70128.1 - 0.0039 16.9 14.7 0.0097 15.6 14.7 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal CcmD PF04995.14 CDJ70129.1 - 0.099 12.7 0.1 0.099 12.7 0.1 4.7 6 0 0 6 6 6 0 Heme exporter protein D (CcmD) DUF573 PF04504.14 CDJ70130.1 - 0.08 13.6 1.6 0.24 12.1 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF573 CAF1A PF12253.8 CDJ70130.1 - 0.57 10.4 17.5 0.29 11.3 14.7 2.1 1 1 0 1 1 1 0 Chromatin assembly factor 1 subunit A MSA-2c PF12238.8 CDJ70130.1 - 2.3 8.2 10.4 5.3 7.0 10.4 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pex14_N PF04695.13 CDJ70132.1 - 0.0017 19.0 10.0 0.0017 19.0 10.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 CDJ70132.1 - 0.0031 16.5 19.9 0.0034 16.4 19.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Connexin PF00029.19 CDJ70132.1 - 0.017 14.9 2.6 0.018 14.8 2.6 1.0 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 CDJ70132.1 - 0.025 14.4 5.0 0.027 14.3 5.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFB6 PF17110.5 CDJ70132.1 - 0.033 13.9 2.3 0.04 13.7 2.3 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Suf PF05843.14 CDJ70132.1 - 0.037 14.0 12.1 0.036 14.0 12.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PIEZO PF15917.5 CDJ70132.1 - 0.06 12.8 9.6 0.067 12.7 9.6 1.0 1 0 0 1 1 1 0 Piezo PAS PF00989.25 CDJ70132.1 - 0.066 13.2 3.4 0.08 12.9 3.4 1.1 1 0 0 1 1 1 0 PAS fold Orf78 PF06024.12 CDJ70132.1 - 0.086 13.1 0.4 0.096 13.0 0.4 1.2 1 0 0 1 1 1 0 Orf78 (ac78) RICTOR_N PF14664.6 CDJ70132.1 - 0.087 11.8 1.1 0.094 11.7 1.1 1.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Rxt3 PF08642.10 CDJ70132.1 - 0.1 13.3 2.8 0.11 13.2 2.8 1.1 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Ctr PF04145.15 CDJ70132.1 - 0.11 13.1 3.5 0.13 12.9 3.5 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Band_3_cyto PF07565.13 CDJ70132.1 - 0.12 12.2 6.2 0.12 12.1 6.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CSG2 PF16965.5 CDJ70132.1 - 0.13 11.2 1.3 0.13 11.2 1.3 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Folate_carrier PF01770.18 CDJ70132.1 - 0.18 10.5 1.7 0.2 10.3 1.7 1.0 1 0 0 1 1 1 0 Reduced folate carrier CCDC53 PF10152.9 CDJ70132.1 - 0.21 12.0 8.4 0.23 11.9 8.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SpoIIP PF07454.11 CDJ70132.1 - 0.28 10.6 8.1 0.28 10.6 8.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CLN3 PF02487.17 CDJ70132.1 - 0.36 9.8 3.2 0.35 9.9 3.2 1.0 1 0 0 1 1 1 0 CLN3 protein CPSF100_C PF13299.6 CDJ70132.1 - 0.41 10.8 5.9 0.44 10.7 5.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Med15 PF09606.10 CDJ70132.1 - 0.41 9.3 26.6 0.42 9.2 26.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MscS_TM PF12794.7 CDJ70132.1 - 0.44 9.4 6.1 0.47 9.3 6.1 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 EOS1 PF12326.8 CDJ70132.1 - 0.5 10.3 2.6 0.54 10.2 2.6 1.1 1 0 0 1 1 1 0 N-glycosylation protein DDHD PF02862.17 CDJ70132.1 - 0.56 10.3 6.5 0.56 10.3 6.5 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 CDJ70132.1 - 0.61 9.3 1.9 0.6 9.3 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Spt20 PF12090.8 CDJ70132.1 - 0.62 9.6 31.3 0.69 9.5 31.3 1.1 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 CDJ70132.1 - 0.69 9.9 6.0 0.77 9.8 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 CDJ70132.1 - 0.75 10.8 11.9 0.97 10.4 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AIF_C PF14721.6 CDJ70132.1 - 1.1 9.7 6.9 1.2 9.5 6.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Hydin_ADK PF17213.3 CDJ70132.1 - 1.1 9.5 8.6 1.1 9.5 8.6 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain EPL1 PF10513.9 CDJ70132.1 - 1.3 9.4 10.8 1.4 9.3 10.8 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like PepSY_TM PF03929.16 CDJ70132.1 - 1.3 8.7 3.6 1.4 8.5 3.6 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Ndc1_Nup PF09531.10 CDJ70132.1 - 1.3 7.6 6.6 1.3 7.6 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4407 PF14362.6 CDJ70132.1 - 1.4 8.2 8.7 1.4 8.2 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM176 PF14851.6 CDJ70132.1 - 1.7 8.3 4.9 1.9 8.1 4.9 1.1 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.8 CDJ70132.1 - 2.2 7.0 9.1 2.2 7.0 9.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.13 CDJ70132.1 - 2.2 8.2 27.7 2.3 8.2 27.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EIIBC-GUT_N PF03612.14 CDJ70132.1 - 2.4 7.9 7.8 2.5 7.8 7.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CobT PF06213.12 CDJ70132.1 - 2.4 7.5 16.9 2.5 7.4 16.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Rrn6 PF10214.9 CDJ70132.1 - 2.9 6.3 12.3 2.9 6.3 12.3 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF5336 PF17270.2 CDJ70132.1 - 3.2 7.3 8.5 4.3 6.9 8.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Androgen_recep PF02166.16 CDJ70132.1 - 4.3 6.1 27.2 4.5 6.0 27.2 1.0 1 0 0 1 1 1 0 Androgen receptor TERB2 PF15101.6 CDJ70132.1 - 5.2 7.1 13.4 5.5 7.0 13.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TMEM51 PF15345.6 CDJ70132.1 - 5.4 6.8 11.4 6.2 6.6 11.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Coilin_N PF15862.5 CDJ70132.1 - 8.4 6.2 14.9 10 5.9 14.9 1.1 1 0 0 1 1 1 0 Coilin N-terminus eIF-3_zeta PF05091.12 CDJ70132.1 - 9 5.1 15.6 9.7 5.0 15.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UPF0560 PF10577.9 CDJ70132.1 - 9.2 4.6 16.4 8.9 4.7 16.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2722 PF10846.8 CDJ70133.1 - 0.0018 17.3 6.7 0.0029 16.7 6.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ70133.1 - 0.22 11.1 17.3 0.31 10.6 17.3 1.1 1 0 0 1 1 1 0 Spt20 family TERB2 PF15101.6 CDJ70133.1 - 0.59 10.1 6.3 0.92 9.5 6.3 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 CDJ70133.1 - 1.3 7.7 3.0 1.9 7.1 3.0 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ70133.1 - 3.6 4.6 5.4 4.4 4.3 5.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Roughex PF06020.11 CDJ70133.1 - 4.8 6.2 8.0 7 5.6 8.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein tRNA-synt_His PF13393.6 CDJ70134.1 - 5.6e-43 147.4 1.8 5.6e-43 147.4 1.8 3.9 2 1 2 4 4 4 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CDJ70134.1 - 1.5e-08 34.7 0.0 3.7e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Spt20 PF12090.8 CDJ70134.1 - 0.00039 20.1 32.3 0.00087 19.0 10.6 3.3 3 0 0 3 3 3 3 Spt20 family RskA PF10099.9 CDJ70134.1 - 0.0055 17.0 4.4 0.0055 17.0 4.4 10.7 5 2 3 8 8 8 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ70134.1 - 0.013 15.5 41.8 0.017 15.2 12.8 3.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit PIP5K PF01504.18 CDJ70134.1 - 0.018 14.2 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase SPX PF03105.19 CDJ70134.1 - 0.057 13.3 21.8 1.8 8.4 4.5 3.3 3 0 0 3 3 3 0 SPX domain Lin-8 PF03353.15 CDJ70134.1 - 0.076 12.6 19.0 0.15 11.6 5.0 3.3 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist DUF2722 PF10846.8 CDJ70134.1 - 0.18 10.7 34.9 0.021 13.8 11.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) SMK-1 PF04802.15 CDJ70135.1 - 5.1e-12 46.0 2.7 1.4e-07 31.5 0.0 2.5 3 0 0 3 3 3 2 Component of IIS longevity pathway SMK-1 SR-25 PF10500.9 CDJ70135.1 - 1.9e-06 27.6 11.0 1.9e-06 27.6 11.0 7.8 7 1 1 8 8 8 4 Nuclear RNA-splicing-associated protein DUF4667 PF15700.5 CDJ70135.1 - 0.00011 22.4 6.1 0.00011 22.4 6.1 7.0 6 1 0 6 6 6 1 Domain of unknown function (DUF4667) RskA PF10099.9 CDJ70135.1 - 0.0064 16.8 8.8 0.0064 16.8 8.8 9.9 3 2 5 9 9 9 2 Anti-sigma-K factor rskA MccV PF17508.2 CDJ70136.1 - 0.03 14.9 0.0 0.052 14.1 0.0 1.4 1 0 0 1 1 1 0 Microcin V bacteriocin SOBP PF15279.6 CDJ70137.1 - 3.8 8.0 13.2 7.3 7.1 13.2 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein XRN_M PF17846.1 CDJ70138.1 - 1.4e-13 50.7 0.1 1.4e-13 50.7 0.1 3.1 3 0 0 3 3 3 1 Xrn1 helical domain Surface_antigen PF11054.8 CDJ70141.1 - 1.4e-61 208.3 0.2 1.8e-61 207.9 0.2 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ70142.1 - 6.2e-77 258.6 0.1 7.2e-77 258.3 0.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Merozoite_SPAM PF07133.11 CDJ70143.1 - 0.22 11.5 5.4 0.66 9.9 5.4 1.7 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SIR2 PF02146.17 CDJ70145.1 - 4.1e-07 30.1 0.0 0.00091 19.2 0.0 3.6 3 0 0 3 3 3 2 Sir2 family LAG1-DNAbind PF09271.11 CDJ70145.1 - 0.0048 17.5 0.1 0.0048 17.5 0.1 3.2 4 0 0 4 4 4 1 LAG1, DNA binding DUF1917 PF08939.10 CDJ70145.1 - 1.2 8.9 4.0 0.32 10.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) WD40 PF00400.32 CDJ70146.1 - 2.8e-08 34.3 8.8 5.7e-05 23.8 0.0 4.9 6 0 0 6 6 6 2 WD domain, G-beta repeat SUIM_assoc PF16619.5 CDJ70147.1 - 0.007 16.4 2.9 0.007 16.4 2.9 16.6 15 3 1 16 16 16 5 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 CDJ70152.1 - 0.039 14.0 2.6 0.039 14.0 2.6 2.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ELYS PF13934.6 CDJ70152.1 - 0.046 13.7 0.4 4.9 7.1 0.0 2.1 1 1 0 2 2 2 0 Nuclear pore complex assembly Glyco_hydro_31 PF01055.26 CDJ70153.1 - 1.7e-85 287.9 0.0 5.5e-85 286.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 CDJ70153.1 - 9e-07 29.1 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Gal_mutarotas_2 PF13802.6 CDJ70153.1 - 2.3e-05 24.6 0.1 7.6e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like V_ATPase_I PF01496.19 CDJ70153.1 - 2.2 6.1 12.5 0.81 7.5 4.2 2.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family OATP PF03137.20 CDJ70153.1 - 2.5 6.3 4.0 14 3.8 0.1 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ras PF00071.22 CDJ70157.1 - 5.1e-40 136.7 0.0 6e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ70157.1 - 2.4e-31 108.4 0.0 2.9e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ70157.1 - 6.5e-12 45.3 0.0 7.4e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ70157.1 - 2.5e-05 23.8 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ70157.1 - 0.00012 22.1 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ70157.1 - 0.00056 19.5 0.1 0.0019 17.8 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CDJ70157.1 - 0.053 12.9 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 CDJ70157.1 - 0.094 12.1 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CDJ70157.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 1 0 1 1 1 0 P-loop containing dynein motor region Ras PF00071.22 CDJ70158.1 - 4.7e-57 192.1 0.0 5.5e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ70158.1 - 2.2e-32 111.8 0.0 3e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ70158.1 - 1.3e-14 54.1 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ70158.1 - 8.5e-06 25.8 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ70158.1 - 8.7e-06 25.4 0.1 0.00088 18.9 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDJ70158.1 - 0.00039 19.9 0.0 0.00049 19.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 CDJ70158.1 - 0.0027 17.5 0.0 0.32 10.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CDJ70158.1 - 0.0032 17.4 0.0 1.8 8.4 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase SRPRB PF09439.10 CDJ70158.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CDJ70158.1 - 0.038 13.5 0.0 0.41 10.2 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 CDJ70158.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CDJ70158.1 - 0.065 13.5 0.0 0.26 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 CDJ70158.1 - 0.089 11.9 0.0 0.19 10.9 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CDJ70158.1 - 0.11 12.2 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CDJ70158.1 - 0.18 12.3 0.1 0.46 11.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AP2 PF00847.20 CDJ70162.1 - 6.7e-05 23.0 2.5 6.7e-05 23.0 2.5 2.3 2 0 0 2 2 2 1 AP2 domain DUF4853 PF16145.5 CDJ70163.1 - 0.027 14.6 0.5 0.051 13.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) TFIIA PF03153.13 CDJ70163.1 - 1.5 8.8 13.6 2.2 8.2 13.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit K_channel_TID PF07941.11 CDJ70163.1 - 3.4 8.2 48.7 4.1 7.9 19.7 2.6 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Spt20 PF12090.8 CDJ70164.1 - 2.1 7.9 46.3 0.044 13.4 21.6 3.4 3 0 0 3 3 3 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ70166.1 - 0.055 12.4 28.7 0.096 11.6 28.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CDK5_activator PF03261.15 CDJ70166.1 - 0.25 10.9 7.0 0.31 10.6 7.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein V_ATPase_I PF01496.19 CDJ70166.1 - 1.6 6.5 9.5 1.8 6.4 9.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNase_PH_C PF03725.15 CDJ70167.1 - 0.0097 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 V_ATPase_I PF01496.19 CDJ70167.1 - 0.099 10.6 13.9 0.039 11.9 0.6 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1980 PF09323.10 CDJ70167.1 - 0.15 11.9 9.7 3.3 7.6 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CCDC-167 PF15188.6 CDJ70167.1 - 0.9 9.9 0.0 0.9 9.9 0.0 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Neur_chan_memb PF02932.16 CDJ70167.1 - 1.6 8.7 5.5 3.1 7.8 2.9 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RcpC PF16976.5 CDJ70168.1 - 0.0035 17.4 0.2 0.0035 17.4 0.2 2.9 3 0 0 3 3 3 1 Flp pilus assembly protein RcpC/CpaB PSK PF06404.12 CDJ70168.1 - 0.035 15.1 2.7 0.035 15.1 2.7 3.1 1 1 1 2 2 2 0 Phytosulfokine precursor protein (PSK) Zip PF02535.22 CDJ70168.1 - 0.15 11.2 2.4 0.18 11.0 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Adeno_PV PF03910.13 CDJ70168.1 - 2.4 6.8 8.5 3.3 6.3 8.5 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV RskA PF10099.9 CDJ70168.1 - 9 6.5 32.0 0.26 11.6 17.5 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA NUDE_C PF04880.13 CDJ70169.1 - 0.36 11.3 2.5 0.36 11.3 2.5 1.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region EMC3_TMCO1 PF01956.16 CDJ70170.1 - 1.7e-16 60.4 2.9 1e-11 44.8 0.6 2.3 2 0 0 2 2 2 2 Integral membrane protein EMC3/TMCO1-like TFIIA PF03153.13 CDJ70171.1 - 0.036 14.1 19.2 0.032 14.2 19.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ70171.1 - 0.043 14.0 4.9 0.046 13.9 4.9 1.1 1 0 0 1 1 1 0 DDHD domain Paramyxo_ncap PF00973.19 CDJ70171.1 - 0.056 12.4 2.4 0.062 12.2 2.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Ureide_permease PF07168.11 CDJ70171.1 - 0.058 12.1 1.3 0.065 12.0 1.3 1.0 1 0 0 1 1 1 0 Ureide permease DUF1980 PF09323.10 CDJ70171.1 - 0.4 10.6 4.3 0.36 10.7 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 CDJ70171.1 - 0.53 9.0 10.0 0.5 9.1 10.0 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ70171.1 - 1.5 8.9 5.7 1.6 8.8 5.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 CDJ70171.1 - 2.2 7.5 12.4 2.1 7.6 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OATP PF03137.20 CDJ70171.1 - 5.7 5.1 4.7 5.9 5.1 4.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Spt20 PF12090.8 CDJ70171.1 - 5.8 6.4 33.4 6.9 6.2 33.4 1.1 1 0 0 1 1 1 0 Spt20 family CSG2 PF16965.5 CDJ70171.1 - 8.9 5.1 5.1 9.6 5.0 5.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Pkinase PF00069.25 CDJ70172.1 - 5.2e-52 176.8 5.2 5.9e-52 176.6 0.0 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ70172.1 - 2e-25 89.6 0.0 2e-25 89.6 0.0 2.7 2 2 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ70172.1 - 1.7e-05 23.8 0.0 1.7e-05 23.8 0.0 2.9 3 0 0 3 3 3 1 Fungal protein kinase MRP-S27 PF10037.9 CDJ70172.1 - 0.13 11.1 28.1 0.23 10.3 28.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 SUIM_assoc PF16619.5 CDJ70172.1 - 0.15 12.1 0.1 0.15 12.1 0.1 7.4 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Herpes_UL87 PF03043.14 CDJ70172.1 - 0.63 8.5 5.7 0.97 7.8 5.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family APH PF01636.23 CDJ70172.1 - 2.9 7.8 0.0 2.9 7.8 0.0 4.5 5 1 0 5 5 5 0 Phosphotransferase enzyme family Dicty_REP PF05086.12 CDJ70172.1 - 3 5.7 15.9 4.4 5.2 15.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein V_ATPase_I PF01496.19 CDJ70172.1 - 5.5 4.8 24.2 9.9 3.9 24.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LAM_C PF12544.8 CDJ70172.1 - 7.9 6.7 8.7 24 5.1 8.4 1.9 2 0 0 2 2 2 0 Lysine-2,3-aminomutase D123 PF07065.14 CDJ70173.1 - 0.029 13.5 5.6 0.032 13.4 5.6 1.0 1 0 0 1 1 1 0 D123 UPF0239 PF06783.11 CDJ70173.1 - 0.032 14.4 3.6 0.035 14.3 3.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Med15 PF09606.10 CDJ70173.1 - 0.088 11.5 28.0 0.09 11.5 28.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_M56 PF05569.11 CDJ70173.1 - 0.2 10.8 0.9 0.22 10.7 0.9 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 Rpp20 PF12328.8 CDJ70173.1 - 0.24 11.3 9.5 0.25 11.3 9.5 1.0 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Presenilin PF01080.17 CDJ70173.1 - 0.28 9.9 9.0 0.3 9.8 9.0 1.0 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 CDJ70173.1 - 0.29 11.1 13.1 0.29 11.2 13.1 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SpoIIP PF07454.11 CDJ70173.1 - 0.35 10.3 10.1 0.33 10.4 10.1 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pex14_N PF04695.13 CDJ70173.1 - 0.56 10.8 16.4 0.53 10.9 16.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.12 CDJ70173.1 - 0.7 8.8 13.0 0.68 8.8 13.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ70173.1 - 0.73 9.8 28.4 0.72 9.8 28.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 CDJ70173.1 - 0.78 9.1 14.1 0.83 9.0 14.1 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CSG2 PF16965.5 CDJ70173.1 - 0.83 8.5 4.1 0.86 8.5 4.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator DDHD PF02862.17 CDJ70173.1 - 0.84 9.7 8.3 0.82 9.8 8.3 1.0 1 0 0 1 1 1 0 DDHD domain Suf PF05843.14 CDJ70173.1 - 0.95 9.4 15.2 0.96 9.4 15.2 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ70173.1 - 0.99 9.4 6.0 0.92 9.5 6.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EIIBC-GUT_N PF03612.14 CDJ70173.1 - 1.1 9.0 9.7 1.2 8.9 9.7 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FHIPEP PF00771.20 CDJ70173.1 - 1.2 7.6 7.1 1.3 7.4 7.1 1.0 1 0 0 1 1 1 0 FHIPEP family EOS1 PF12326.8 CDJ70173.1 - 1.2 9.1 3.8 1.2 9.1 3.8 1.1 1 0 0 1 1 1 0 N-glycosylation protein V_ATPase_I PF01496.19 CDJ70173.1 - 1.2 6.9 9.7 1.3 6.8 9.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Band_3_cyto PF07565.13 CDJ70173.1 - 1.4 8.7 8.2 1.4 8.7 8.2 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF973 PF06157.11 CDJ70173.1 - 1.6 7.7 5.0 1.6 7.7 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DcuA_DcuB PF03605.14 CDJ70173.1 - 1.7 7.5 3.9 1.9 7.3 3.9 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF4834 PF16118.5 CDJ70173.1 - 1.7 9.6 13.4 2.3 9.3 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AIF_C PF14721.6 CDJ70173.1 - 1.8 8.9 8.4 2.1 8.7 8.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TMEM208_SND2 PF05620.11 CDJ70173.1 - 1.8 8.3 8.5 2.2 8.1 8.5 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF3276 PF11680.8 CDJ70173.1 - 1.9 8.6 8.3 2.3 8.4 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Ctr PF04145.15 CDJ70173.1 - 1.9 9.1 4.3 1.9 9.1 4.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Connexin PF00029.19 CDJ70173.1 - 2.3 7.9 7.6 2.6 7.7 7.6 1.0 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 CDJ70173.1 - 2.4 7.0 5.4 2.3 7.1 5.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM176 PF14851.6 CDJ70173.1 - 2.7 7.6 6.0 3.2 7.4 6.0 1.1 1 0 0 1 1 1 0 FAM176 family CLN3 PF02487.17 CDJ70173.1 - 3 6.8 7.2 3.3 6.6 7.2 1.0 1 0 0 1 1 1 0 CLN3 protein Spt20 PF12090.8 CDJ70173.1 - 3.1 7.3 37.4 3.7 7.1 37.4 1.1 1 0 0 1 1 1 0 Spt20 family OATP PF03137.20 CDJ70173.1 - 3.8 5.7 6.1 3.7 5.7 6.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family YhfC PF10086.9 CDJ70173.1 - 4.1 6.7 6.1 4.8 6.5 6.1 1.0 1 0 0 1 1 1 0 YhfC intramembrane metalloprotease PigN PF04987.14 CDJ70173.1 - 5.3 5.8 5.2 5.7 5.7 5.2 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Coilin_N PF15862.5 CDJ70173.1 - 6.2 6.6 14.5 7.2 6.4 14.5 1.1 1 0 0 1 1 1 0 Coilin N-terminus Rsc14 PF08586.10 CDJ70173.1 - 6.8 7.6 9.3 9.5 7.1 9.3 1.2 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit Ureide_permease PF07168.11 CDJ70173.1 - 9.1 4.9 6.0 10 4.7 6.0 1.0 1 0 0 1 1 1 0 Ureide permease TFIIA PF03153.13 CDJ70174.1 - 0.0012 18.9 25.3 0.0012 18.9 25.3 7.7 5 1 2 7 7 7 2 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 CDJ70174.1 - 0.0012 19.4 1.5 0.0012 19.4 1.5 6.1 5 1 0 5 5 5 1 AAA domain Suf PF05843.14 CDJ70174.1 - 0.0014 18.7 6.2 0.0014 18.7 6.2 6.2 6 1 1 7 7 7 2 Suppressor of forked protein (Suf) SUIM_assoc PF16619.5 CDJ70174.1 - 0.0038 17.3 2.3 0.0038 17.3 2.3 12.7 8 4 2 10 10 10 2 Unstructured region C-term to UIM in Ataxin3 TPR_7 PF13176.6 CDJ70174.1 - 0.069 13.2 0.4 0.54 10.4 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SPX PF03105.19 CDJ70174.1 - 0.33 10.8 0.0 0.33 10.8 0.0 6.7 4 3 0 4 4 4 0 SPX domain DUF2722 PF10846.8 CDJ70175.1 - 0.12 11.3 22.6 0.16 10.9 22.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Rxt3 PF08642.10 CDJ70175.1 - 0.21 12.3 2.5 0.32 11.8 2.5 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Seryl_tRNA_N PF02403.22 CDJ70175.1 - 0.22 11.8 22.9 2 8.7 17.2 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF913 PF06025.12 CDJ70175.1 - 0.24 10.4 5.9 0.27 10.2 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) YL1 PF05764.13 CDJ70175.1 - 0.3 11.2 24.7 0.34 11.0 24.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SpoIIP PF07454.11 CDJ70175.1 - 0.32 10.4 8.2 0.39 10.1 8.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4746 PF15928.5 CDJ70175.1 - 0.35 10.2 8.3 0.41 10.0 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Folliculin PF11704.8 CDJ70175.1 - 0.37 10.6 11.9 0.5 10.2 11.9 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport MMR1 PF08505.10 CDJ70175.1 - 0.54 10.5 14.5 0.63 10.3 14.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein MTBP_C PF14920.6 CDJ70175.1 - 0.54 10.0 13.2 0.65 9.7 13.2 1.1 1 0 0 1 1 1 0 MDM2-binding DDHD PF02862.17 CDJ70175.1 - 0.62 10.2 10.6 0.74 9.9 10.6 1.1 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.13 CDJ70175.1 - 0.82 9.4 11.5 1 9.1 11.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TFIIA PF03153.13 CDJ70175.1 - 0.87 9.5 28.9 1.1 9.1 28.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ70175.1 - 0.94 9.5 8.4 1 9.4 8.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ESM4 PF15952.5 CDJ70175.1 - 1.1 9.6 19.1 1.4 9.3 19.1 1.1 1 0 0 1 1 1 0 Enhancer of split M4 family TCP PF03634.13 CDJ70175.1 - 1.2 9.7 18.9 1.6 9.3 18.9 1.1 1 0 0 1 1 1 0 TCP family transcription factor Ndc1_Nup PF09531.10 CDJ70175.1 - 1.6 7.3 10.5 1.7 7.2 10.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EPL1 PF10513.9 CDJ70175.1 - 1.8 9.0 11.9 2.4 8.5 11.9 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like ATAD4 PF15321.6 CDJ70175.1 - 1.8 9.9 10.8 3.3 9.1 10.2 1.6 2 0 0 2 2 1 0 ATPase family AAA domain containing 4 Gti1_Pac2 PF09729.9 CDJ70175.1 - 1.9 8.5 10.4 2.6 8.1 10.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family FPN1 PF06963.12 CDJ70175.1 - 2.1 6.8 4.1 2.5 6.6 4.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) RR_TM4-6 PF06459.12 CDJ70175.1 - 2.4 7.9 11.3 2.7 7.7 11.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TERB2 PF15101.6 CDJ70175.1 - 2.5 8.1 15.6 3.5 7.6 15.6 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SET PF00856.28 CDJ70175.1 - 2.6 8.4 4.2 3.5 8.0 4.2 1.3 1 0 0 1 1 1 0 SET domain FAM60A PF15396.6 CDJ70175.1 - 2.8 7.9 7.8 3.2 7.7 7.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Roughex PF06020.11 CDJ70175.1 - 2.8 6.9 10.5 3.1 6.8 10.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein eIF-3_zeta PF05091.12 CDJ70175.1 - 3.1 6.7 14.7 3.2 6.6 14.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CCDC53 PF10152.9 CDJ70175.1 - 3.2 8.1 13.6 4 7.8 13.6 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Peptidase_S46 PF10459.9 CDJ70175.1 - 3.4 6.2 13.1 3.8 6.0 13.1 1.1 1 0 0 1 1 1 0 Peptidase S46 ATG22 PF11700.8 CDJ70175.1 - 3.4 6.2 4.8 4.3 5.8 4.8 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF572 PF04502.13 CDJ70175.1 - 3.6 7.1 15.0 4.9 6.7 15.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAT1 PF09770.9 CDJ70175.1 - 3.6 5.7 22.2 4.2 5.5 22.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ALMT PF11744.8 CDJ70175.1 - 3.7 6.3 12.8 4.3 6.1 12.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Connexin PF00029.19 CDJ70175.1 - 3.8 7.2 6.8 4.3 7.0 6.8 1.2 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ70175.1 - 3.8 6.2 15.8 4.6 5.9 15.8 1.1 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 CDJ70175.1 - 4.4 7.6 15.6 5.6 7.3 15.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop53 PF07767.11 CDJ70175.1 - 4.5 6.6 24.6 6.5 6.0 24.6 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) XRN_M PF17846.1 CDJ70175.1 - 4.5 6.1 10.1 5.2 5.9 10.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain SprA-related PF12118.8 CDJ70175.1 - 4.8 6.2 25.3 5.3 6.1 25.3 1.1 1 0 0 1 1 1 0 SprA-related family Sec62 PF03839.16 CDJ70175.1 - 5.1 6.5 11.1 6.8 6.1 11.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Vps39_2 PF10367.9 CDJ70175.1 - 5.8 7.4 10.3 2.3 8.7 7.9 1.5 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Paf1 PF03985.13 CDJ70175.1 - 5.9 5.8 18.1 6.6 5.6 18.1 1.0 1 0 0 1 1 1 0 Paf1 SID-1_RNA_chan PF13965.6 CDJ70175.1 - 6.2 5.1 4.8 6.5 5.0 4.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CAF1 PF04857.20 CDJ70175.1 - 6.4 5.8 8.9 8 5.5 8.9 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease MPM1 PF17234.2 CDJ70175.1 - 7.9 6.7 12.9 13 6.0 12.9 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Ctr PF04145.15 CDJ70175.1 - 8.1 7.1 8.9 12 6.5 8.9 1.3 1 0 0 1 1 1 0 Ctr copper transporter family DUF2828 PF11443.8 CDJ70175.1 - 8.8 4.3 13.1 10 4.1 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Mem_trans PF03547.18 CDJ70175.1 - 9.7 4.5 6.8 12 4.1 6.8 1.1 1 0 0 1 1 1 0 Membrane transport protein SR-25 PF10500.9 CDJ70177.1 - 0.0046 16.6 25.4 0.0064 16.1 25.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ70177.1 - 0.0059 15.6 27.9 0.0075 15.3 27.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Asparaginase_2 PF01112.18 CDJ70177.1 - 0.052 12.6 1.8 0.063 12.3 1.8 1.1 1 0 0 1 1 1 0 Asparaginase Spt20 PF12090.8 CDJ70177.1 - 0.064 12.9 34.8 0.084 12.5 34.8 1.2 1 0 0 1 1 1 0 Spt20 family DUF4667 PF15700.5 CDJ70177.1 - 0.071 13.2 21.4 0.09 12.9 21.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) UPF0524 PF15823.5 CDJ70177.1 - 0.087 12.2 9.9 0.12 11.8 9.9 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 DUF2367 PF10164.9 CDJ70177.1 - 0.097 13.2 5.8 0.12 12.9 5.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) DUF702 PF05142.12 CDJ70177.1 - 0.12 12.8 14.7 0.17 12.3 14.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) TFIIA PF03153.13 CDJ70177.1 - 0.18 11.8 34.5 0.18 11.7 34.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ70177.1 - 0.18 11.3 19.8 0.21 11.1 19.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BAT2_N PF07001.11 CDJ70177.1 - 0.22 12.0 21.6 0.27 11.7 21.6 1.1 1 0 0 1 1 1 0 BAT2 N-terminus DUF3292 PF11696.8 CDJ70177.1 - 0.23 9.8 3.8 0.22 9.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Macoilin PF09726.9 CDJ70177.1 - 0.35 9.4 18.8 0.42 9.1 18.8 1.0 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 CDJ70177.1 - 0.37 8.5 11.8 0.43 8.3 11.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4175 PF13779.6 CDJ70177.1 - 0.5 8.2 22.6 0.41 8.5 22.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pox_G7 PF05503.12 CDJ70177.1 - 0.61 9.0 4.2 0.68 8.8 4.2 1.0 1 0 0 1 1 1 0 Poxvirus G7-like MPM1 PF17234.2 CDJ70177.1 - 0.81 9.9 13.9 1 9.6 13.9 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF4407 PF14362.6 CDJ70177.1 - 0.82 9.0 12.9 1.1 8.6 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1645 PF07816.11 CDJ70177.1 - 0.88 10.1 19.1 1.2 9.7 19.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Herpes_pp85 PF04637.12 CDJ70177.1 - 1 7.7 7.5 0.99 7.7 7.5 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) GREB1 PF15782.5 CDJ70177.1 - 1.1 6.3 23.9 1.2 6.2 23.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PepSY_TM PF03929.16 CDJ70177.1 - 1.4 8.6 5.3 1.3 8.6 5.3 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Roughex PF06020.11 CDJ70177.1 - 1.5 7.8 12.5 2 7.4 12.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein eIF-3_zeta PF05091.12 CDJ70177.1 - 1.7 7.6 16.6 1.6 7.6 16.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FHIPEP PF00771.20 CDJ70177.1 - 1.7 7.0 5.7 1.8 6.9 5.7 1.0 1 0 0 1 1 1 0 FHIPEP family Apt1 PF10351.9 CDJ70177.1 - 1.7 7.4 20.6 2 7.2 20.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAT1 PF09770.9 CDJ70177.1 - 2.3 6.4 26.5 2.3 6.4 26.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4770 PF15994.5 CDJ70177.1 - 3.5 7.8 14.1 4.3 7.5 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) SPX PF03105.19 CDJ70177.1 - 3.6 7.4 22.6 4 7.2 22.6 1.0 1 0 0 1 1 1 0 SPX domain SLC12 PF03522.15 CDJ70177.1 - 4.1 6.3 15.1 4.8 6.1 15.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SRP-alpha_N PF04086.13 CDJ70177.1 - 4.9 7.0 18.0 5.4 6.8 18.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Peptidase_S64 PF08192.11 CDJ70177.1 - 5.4 5.4 20.0 6.1 5.2 20.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 CDJ70177.1 - 6.9 5.3 21.7 7.1 5.3 21.7 1.0 1 0 0 1 1 1 0 Presenilin BORG_CEP PF14957.6 CDJ70177.1 - 7.6 7.7 17.3 8.7 7.5 17.3 1.1 1 0 0 1 1 1 0 Cdc42 effector Sec62 PF03839.16 CDJ70177.1 - 8.9 5.8 9.1 11 5.5 9.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Totivirus_coat PF05518.11 CDJ70177.1 - 9.2 4.2 9.3 9.4 4.1 9.3 1.0 1 0 0 1 1 1 0 Totivirus coat protein Ribosomal_L28e PF01778.17 CDJ70178.1 - 2.4e-28 99.2 0.9 2.4e-28 99.2 0.9 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CDJ70178.1 - 5.2e-16 59.1 11.7 5.2e-16 59.1 11.7 2.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region SR-25 PF10500.9 CDJ70179.1 - 0.00034 20.3 14.8 0.00038 20.2 7.9 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.8 CDJ70179.1 - 0.001 18.2 16.9 0.001 18.2 16.9 3.2 2 1 0 2 2 2 1 Transcriptional activator LAG-3 PrsW-protease PF13367.6 CDJ70179.1 - 0.015 14.7 16.2 0.18 11.3 5.3 3.8 4 0 0 4 4 4 0 PrsW family intramembrane metalloprotease DUF4667 PF15700.5 CDJ70179.1 - 0.12 12.5 0.1 0.12 12.5 0.1 3.2 3 2 0 3 3 3 0 Domain of unknown function (DUF4667) Pkinase PF00069.25 CDJ70180.1 - 2.1e-68 230.6 0.0 4.3e-68 229.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ70180.1 - 2.9e-33 115.3 0.0 6e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCHC_6 PF15288.6 CDJ70180.1 - 0.037 13.9 0.0 0.16 11.8 0.0 2.1 1 0 0 1 1 1 0 Zinc knuckle Pkinase_fungal PF17667.1 CDJ70180.1 - 0.56 8.9 0.0 0.56 8.9 0.0 3.4 4 1 0 4 4 4 0 Fungal protein kinase zf-CCHC PF00098.23 CDJ70181.1 - 2.3e-08 33.8 12.5 2.6e-06 27.2 2.3 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ70181.1 - 0.0015 18.5 0.6 0.0015 18.5 0.6 2.5 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ70181.1 - 0.0019 18.0 0.5 0.0019 18.0 0.5 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ70181.1 - 0.018 14.9 2.1 0.018 14.9 2.1 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ70181.1 - 0.097 12.4 7.6 0.32 10.8 0.6 2.7 3 0 0 3 3 3 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CDJ70181.1 - 0.6 10.5 10.1 1.4 9.3 10.1 1.6 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_5 PF14787.6 CDJ70181.1 - 0.63 9.8 10.0 0.84 9.4 1.0 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVP_2 PF08284.11 CDJ70182.1 - 8e-11 41.9 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ70182.1 - 2.6e-10 40.8 0.0 5.8e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ70182.1 - 1.4e-08 35.2 0.0 3.2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ70182.1 - 0.014 15.7 0.0 0.044 14.1 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ70182.1 - 0.037 13.8 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 CDJ70183.1 - 2.3e-28 98.1 0.0 4.1e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ70183.1 - 6e-28 97.2 0.0 1.1e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ70183.1 - 7e-20 71.5 0.0 1.2e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM92 PF06730.11 CDJ70183.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 FAM92 protein Hexokinase_1 PF00349.21 CDJ70184.1 - 3.6e-58 196.8 0.0 6.3e-58 196.0 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 CDJ70184.1 - 6e-07 29.1 1.0 1.1e-06 28.2 0.1 2.0 2 0 0 2 2 2 1 Hexokinase VanY PF02557.17 CDJ70184.1 - 0.011 15.6 0.0 0.041 13.7 0.0 2.0 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase SR-25 PF10500.9 CDJ70184.1 - 2.1 7.9 19.8 1.4 8.5 12.9 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.10 CDJ70184.1 - 9.4 6.3 10.9 3.6e+02 1.1 10.9 2.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF2009 PF09418.10 CDJ70185.1 - 6.1e-101 338.7 4.3 1.3e-68 232.1 0.0 4.0 2 2 1 3 3 3 3 Protein of unknown function (DUF2009) DUF755 PF05501.11 CDJ70185.1 - 0.0043 17.3 7.7 0.0043 17.3 7.7 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF755) DUF4148 PF13663.6 CDJ70185.1 - 0.036 14.3 5.4 2 8.7 2.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF5336 PF17270.2 CDJ70185.1 - 0.056 13.1 2.5 0.11 12.1 2.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5336) SLATT_1 PF18181.1 CDJ70185.1 - 0.52 10.2 5.4 0.34 10.8 2.9 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Apt1 PF10351.9 CDJ70185.1 - 0.59 8.9 14.0 1.4 7.7 7.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4667 PF15700.5 CDJ70185.1 - 0.88 9.6 23.2 0.29 11.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Velvet PF11754.8 CDJ70185.1 - 1.1 9.1 6.2 3.8 7.4 3.0 2.2 2 0 0 2 2 2 0 Velvet factor Macoilin PF09726.9 CDJ70185.1 - 1.9 7.0 18.2 0.71 8.4 8.3 2.3 2 0 0 2 2 2 0 Macoilin family CDC45 PF02724.14 CDJ70186.1 - 2.9 6.1 23.1 3.4 5.8 23.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ70186.1 - 4.4 5.9 29.0 6.2 5.5 29.0 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ70186.1 - 5.9 5.8 25.4 6.6 5.6 25.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 TMEM51 PF15345.6 CDJ70187.1 - 0.0014 18.6 0.1 0.0016 18.3 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 OAD_gamma PF04277.13 CDJ70187.1 - 0.0017 18.9 0.0 0.0031 18.1 0.0 1.5 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain BatD PF13584.6 CDJ70187.1 - 0.017 14.0 0.1 0.023 13.5 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF3328 PF11807.8 CDJ70187.1 - 0.021 14.6 0.3 0.03 14.1 0.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) DUF2448 PF10476.9 CDJ70187.1 - 0.021 14.7 1.9 0.026 14.4 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Cadherin_C_2 PF16492.5 CDJ70187.1 - 0.028 15.2 0.1 0.062 14.1 0.1 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 CDJ70187.1 - 0.066 14.1 0.0 0.15 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain COX15-CtaA PF02628.15 CDJ70188.1 - 1.5e-29 103.1 1.8 1.7e-29 102.9 1.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Ribosomal_60s PF00428.19 CDJ70188.1 - 0.021 15.4 9.4 0.032 14.8 9.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF773 PF05600.12 CDJ70189.1 - 1.7e-40 139.3 26.7 1.7e-40 139.3 26.7 3.3 2 2 0 2 2 2 1 CDK5 regulatory subunit-associated protein 3 Androgen_recep PF02166.16 CDJ70189.1 - 0.0034 16.3 8.5 0.0034 16.3 8.5 5.9 3 2 3 6 6 6 1 Androgen receptor EF-hand_1 PF00036.32 CDJ70190.1 - 3.1e-22 76.4 9.4 5e-08 31.9 1.8 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CDJ70190.1 - 8e-20 71.1 6.8 8e-15 55.1 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ70190.1 - 8.7e-19 65.8 6.2 1.3e-05 24.8 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CDJ70190.1 - 1.6e-14 53.5 7.2 5.2e-11 42.2 0.8 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 CDJ70190.1 - 9.3e-10 38.7 0.3 1.6e-06 28.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ70190.1 - 2.4e-09 36.2 6.3 4e-06 26.1 0.8 3.3 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 CDJ70190.1 - 0.0036 17.1 3.4 0.0041 16.9 0.2 2.1 2 0 0 2 2 2 1 EF hand SHOCT PF09851.9 CDJ70190.1 - 0.0096 15.6 1.2 0.79 9.5 0.1 3.0 2 0 0 2 2 2 1 Short C-terminal domain Staphylokinase PF02821.16 CDJ70190.1 - 0.01 16.3 0.3 0.028 14.9 0.1 1.6 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family EF-hand_4 PF12763.7 CDJ70190.1 - 0.022 14.7 1.8 0.41 10.6 0.7 2.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.17 CDJ70190.1 - 0.074 13.7 2.0 0.087 13.4 1.3 1.5 2 0 0 2 2 1 0 MgtE intracellular N domain RST PF12174.8 CDJ70190.1 - 0.095 12.6 0.2 1.4 8.9 0.0 2.4 1 1 2 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain DUF1636 PF07845.11 CDJ70190.1 - 0.17 12.4 0.0 2.8 8.4 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1636) PhetRS_B1 PF18262.1 CDJ70190.1 - 0.22 11.8 2.9 0.29 11.4 0.4 2.2 1 1 2 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain IMUP PF15761.5 CDJ70192.1 - 5.4 7.7 6.5 0.82 10.4 1.6 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF3786 PF12654.7 CDJ70193.1 - 0.068 12.8 0.1 5.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) DUF755 PF05501.11 CDJ70193.1 - 0.92 9.8 35.8 0.31 11.3 9.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF755) PSD1 PF07587.11 CDJ70195.1 - 0.078 12.5 7.4 0.72 9.3 7.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1553) EspB_PE PF18625.1 CDJ70195.1 - 0.11 12.9 3.8 0.19 12.2 1.9 2.5 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain DUF883 PF05957.13 CDJ70195.1 - 3 8.5 18.9 2.3 8.9 0.5 4.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF3774 PF12609.8 CDJ70195.1 - 6.7 7.8 0.0 6.7 7.8 0.0 4.0 4 1 0 4 4 4 0 Wound-induced protein zf-C4H2 PF10146.9 CDJ70195.1 - 7.8 6.7 10.8 3.2 8.0 6.9 2.4 2 1 0 2 2 2 0 Zinc finger-containing protein MBF1 PF08523.10 CDJ70197.1 - 1.4e-19 70.3 0.8 1.4e-19 70.3 0.8 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CDJ70197.1 - 8.2e-15 54.6 0.1 1.3e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 CDJ70197.1 - 7.7e-07 29.0 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 CDJ70197.1 - 8.9e-07 29.2 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 CDJ70197.1 - 0.00028 21.3 0.0 0.00048 20.5 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 CDJ70197.1 - 0.012 15.6 0.1 0.027 14.4 0.1 1.6 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 CDJ70197.1 - 0.014 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_25 PF13413.6 CDJ70197.1 - 0.04 13.8 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 CDJ70197.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding UPF0203 PF05254.12 CDJ70198.1 - 0.0033 17.7 0.0 0.0034 17.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Transketolase_N PF00456.21 CDJ70199.1 - 2.6e-144 480.3 0.0 3.7e-144 479.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CDJ70199.1 - 9.5e-37 126.4 0.0 1.5e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDJ70199.1 - 4.5e-05 23.3 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CDJ70199.1 - 0.00044 19.5 0.0 0.00078 18.7 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 CDJ70199.1 - 0.097 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Integrase_H2C2 PF17921.1 CDJ70203.1 - 7.9e-07 29.1 0.2 1.7e-06 28.0 0.1 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain GTSE1_N PF15259.6 CDJ70204.1 - 0.13 12.4 0.1 0.36 11.0 0.1 1.7 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 IMUP PF15761.5 CDJ70207.1 - 0.016 15.9 9.3 0.016 15.9 9.3 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein Macoilin PF09726.9 CDJ70207.1 - 1.2 7.6 15.7 1.6 7.2 15.7 1.1 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 CDJ70207.1 - 1.4 7.8 16.5 1.6 7.6 16.5 1.1 1 0 0 1 1 1 0 Mitoguardin RIFIN PF02009.16 CDJ70207.1 - 1.8 8.3 12.9 2.1 8.2 12.9 1.1 1 0 0 1 1 1 0 Rifin ADP_ribosyl_GH PF03747.14 CDJ70207.1 - 2.3 7.9 11.2 3.3 7.3 11.2 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Alpha_GJ PF03229.13 CDJ70207.1 - 9.4 6.8 25.4 2.2 8.9 2.4 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J AAA_23 PF13476.6 CDJ70209.1 - 0.039 14.4 0.1 0.039 14.4 0.1 6.7 3 2 1 4 4 4 0 AAA domain PI_PP_I PF18363.1 CDJ70209.1 - 5.7 7.2 9.3 0.22 11.7 0.3 3.1 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain RskA PF10099.9 CDJ70210.1 - 0.0004 20.7 9.7 0.0004 20.7 9.7 4.5 2 1 2 4 4 4 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ70210.1 - 0.0044 16.7 38.6 0.0047 16.6 13.6 2.3 2 0 0 2 2 2 2 Spt20 family Peroxin-13_N PF04088.13 CDJ70210.1 - 0.12 12.6 4.2 7.8 6.8 0.5 2.5 2 0 0 2 2 2 0 Peroxin 13, N-terminal region eIF-3_zeta PF05091.12 CDJ70210.1 - 1 8.3 12.8 0.6 9.0 0.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIP5K PF01504.18 CDJ70210.1 - 1.6 7.9 6.0 7 5.8 0.5 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Comm PF15957.5 CDJ70210.1 - 7.9 6.9 7.5 22 5.4 0.9 2.6 2 0 0 2 2 2 0 Commissureless Pox_A3L PF05288.11 CDJ70212.1 - 0.098 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A3L Protein SUIM_assoc PF16619.5 CDJ70213.1 - 0.0014 18.7 6.0 0.0014 18.7 6.0 7.1 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Peptidase_C92 PF05708.12 CDJ70213.1 - 0.0016 18.5 0.0 0.0016 18.5 0.0 2.3 2 0 0 2 2 2 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF755 PF05501.11 CDJ70213.1 - 0.0027 18.0 17.0 0.0027 18.0 17.0 5.5 3 2 1 4 4 4 1 Domain of unknown function (DUF755) Plasmodium_Vir PF05795.11 CDJ70215.1 - 0.16 11.3 3.8 0.21 11.0 3.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 CDJ70215.1 - 0.19 11.6 14.9 0.26 11.2 14.9 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ70215.1 - 0.2 10.5 14.4 0.25 10.2 14.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ70215.1 - 0.59 8.8 4.6 0.79 8.4 4.6 1.1 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 CDJ70215.1 - 1.3 8.2 15.1 1.6 7.8 15.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Telomerase_RBD PF12009.8 CDJ70217.1 - 4.7e-28 98.0 0.0 4.7e-28 98.0 0.0 3.2 2 1 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain SR-25 PF10500.9 CDJ70217.1 - 1.4e-05 24.9 12.9 1.4e-05 24.9 12.9 14.5 12 3 3 15 15 15 2 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ70218.1 - 4.3e-06 26.5 13.0 4.3e-06 26.5 13.0 4.6 5 1 0 5 5 5 1 Nuclear RNA-splicing-associated protein PRCC PF10253.9 CDJ70218.1 - 0.013 16.3 0.6 0.013 16.3 0.6 4.2 3 1 0 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting RVT_1 PF00078.27 CDJ70218.1 - 0.032 13.8 0.0 8.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Neur_chan_memb PF02932.16 CDJ70218.1 - 0.65 10.0 8.7 1.7 8.6 3.2 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 CDJ70218.1 - 1.1 7.9 4.6 3.2 6.5 4.6 1.7 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Velvet PF11754.8 CDJ70218.1 - 2.8 7.8 26.4 0.8 9.6 13.2 3.3 3 0 0 3 3 3 0 Velvet factor Zip PF02535.22 CDJ70218.1 - 3.9 6.6 5.8 4 6.6 4.3 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Suf PF05843.14 CDJ70218.1 - 6.2 6.7 25.9 0.23 11.4 8.0 2.8 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) SQHop_cyclase_N PF13249.6 CDJ70219.1 - 0.051 12.7 0.0 0.051 12.7 0.0 1.0 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain DUF2956 PF11169.8 CDJ70221.1 - 0.03 14.5 0.6 0.03 14.5 0.6 4.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2956) CCDC53 PF10152.9 CDJ70221.1 - 0.079 13.4 0.0 0.079 13.4 0.0 5.7 2 1 1 3 3 3 0 Subunit CCDC53 of WASH complex DUF812 PF05667.11 CDJ70221.1 - 0.72 8.7 30.3 1.2 7.9 30.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) EphA2_TM PF14575.6 CDJ70221.1 - 4.7 8.2 17.2 5.3 8.0 0.0 4.7 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain YlbD_coat PF14071.6 CDJ70221.1 - 5.6 7.2 30.5 1.5 9.1 5.1 3.0 3 0 0 3 3 3 0 Putative coat protein NPL PF17800.1 CDJ70222.1 - 4.3e-11 43.3 0.0 8.7e-11 42.3 0.0 1.5 2 0 0 2 2 2 1 Nucleoplasmin-like domain Ribosomal_60s PF00428.19 CDJ70222.1 - 0.097 13.3 10.5 0.051 14.2 8.3 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DEAD PF00270.29 CDJ70224.1 - 1.1e-24 87.2 0.0 1.6e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ70224.1 - 0.071 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SPX PF03105.19 CDJ70224.1 - 0.65 9.9 2.5 0.85 9.5 2.5 1.1 1 0 0 1 1 1 0 SPX domain LMBR1 PF04791.16 CDJ70225.1 - 0.0012 17.8 0.7 0.0014 17.7 0.7 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF3464 PF11947.8 CDJ70225.1 - 0.0072 16.1 3.6 0.0072 16.1 3.6 1.8 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 DUF2477 PF10631.9 CDJ70225.1 - 0.011 16.4 29.7 0.011 16.4 29.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) MDM10 PF12519.8 CDJ70225.1 - 0.018 13.9 0.9 0.015 14.2 0.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Presenilin PF01080.17 CDJ70225.1 - 0.019 13.8 10.2 0.023 13.5 10.2 1.2 1 1 0 1 1 1 0 Presenilin Anoctamin PF04547.12 CDJ70225.1 - 0.021 13.7 0.3 0.025 13.4 0.3 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF747 PF05346.11 CDJ70225.1 - 0.13 11.7 0.5 0.15 11.5 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic membrane protein family FAM176 PF14851.6 CDJ70225.1 - 0.27 10.9 5.7 0.61 9.8 5.7 1.6 1 0 0 1 1 1 0 FAM176 family V_ATPase_I PF01496.19 CDJ70225.1 - 0.33 8.8 15.1 2.4 6.0 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FAM91_C PF14648.6 CDJ70225.1 - 0.51 9.1 4.7 0.64 8.8 4.7 1.1 1 0 0 1 1 1 0 FAM91 C-terminus RskA PF10099.9 CDJ70225.1 - 4 7.7 19.4 20 5.4 17.3 2.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Sec62 PF03839.16 CDJ70225.1 - 4.8 6.6 7.3 8.9 5.8 7.3 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 CCDC53 PF10152.9 CDJ70225.1 - 5.6 7.4 17.8 5.8 7.3 10.8 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RBM39linker PF15519.6 CDJ70225.1 - 6.8 7.9 16.1 0.71 11.0 6.7 2.2 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF2721 PF11026.8 CDJ70225.1 - 7.7 6.4 16.1 19 5.1 16.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) DUF5327 PF17261.2 CDJ70225.1 - 8.6 7.2 22.8 33 5.3 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DEAD PF00270.29 CDJ70226.1 - 5.6e-24 84.9 0.3 5.6e-24 84.9 0.3 3.9 4 1 1 5 5 5 2 DEAD/DEAH box helicase IMUP PF15761.5 CDJ70226.1 - 0.0053 17.4 2.7 0.0053 17.4 2.7 7.8 5 2 3 8 8 8 2 Immortalisation up-regulated protein Nop14 PF04147.12 CDJ70227.1 - 0.26 9.5 20.3 0.31 9.2 20.3 1.0 1 0 0 1 1 1 0 Nop14-like family Asp-B-Hydro_N PF05279.11 CDJ70227.1 - 0.99 9.4 13.0 1.3 9.1 13.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_S8_N PF16361.5 CDJ70227.1 - 1.7 9.1 5.7 5.9 7.4 5.7 1.9 1 0 0 1 1 1 0 N-terminal of Subtilase family Utp14 PF04615.13 CDJ70227.1 - 2.5 6.6 26.1 2.7 6.5 26.1 1.1 1 0 0 1 1 1 0 Utp14 protein SR-25 PF10500.9 CDJ70228.1 - 0.00015 21.4 9.4 0.00015 21.4 9.4 10.6 9 1 3 12 12 12 6 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ70229.1 - 5.5e-05 22.9 34.7 0.0023 17.6 13.3 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ70229.1 - 7.7e-05 23.3 26.9 0.007 17.0 8.8 2.2 2 0 0 2 2 2 2 Immortalisation up-regulated protein ORC_WH_C PF18137.1 CDJ70229.1 - 0.041 13.9 6.4 0.056 13.5 6.4 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal MMR1 PF08505.10 CDJ70229.1 - 0.63 10.3 19.3 2 8.6 8.8 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein CDC45 PF02724.14 CDJ70229.1 - 0.83 7.9 11.6 1 7.6 11.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Hydin_ADK PF17213.3 CDJ70229.1 - 1.2 9.4 16.0 1.5 9.0 16.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF4407 PF14362.6 CDJ70229.1 - 1.3 8.3 9.3 1.7 8.0 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RskA PF10099.9 CDJ70229.1 - 2.5 8.3 22.2 3.9 7.7 22.2 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA LPP20 PF02169.16 CDJ70229.1 - 3 8.2 22.0 0.12 12.8 10.8 2.2 2 0 0 2 2 2 0 LPP20 lipoprotein DUF2967 PF11179.8 CDJ70229.1 - 4.1 5.4 35.6 1.2 7.2 17.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) Spt5_N PF11942.8 CDJ70229.1 - 5 8.2 10.6 4.6 8.3 5.7 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal GREB1 PF15782.5 CDJ70229.1 - 8.1 3.4 20.2 9.6 3.2 20.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Roughex PF06020.11 CDJ70229.1 - 9 5.3 14.3 2.2 7.3 8.8 2.0 2 0 0 2 2 2 0 Drosophila roughex protein SPRY PF00622.28 CDJ70230.1 - 0.0007 19.7 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 SPRY domain RVP_2 PF08284.11 CDJ70231.1 - 6.4e-11 42.2 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 CDJ70231.1 - 1.1e-08 34.8 12.0 1.4e-06 28.1 2.0 2.6 2 0 0 2 2 2 2 Zinc knuckle Asp_protease_2 PF13650.6 CDJ70231.1 - 1.1e-08 35.6 0.0 2.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ70231.1 - 3e-08 34.1 0.0 6.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 CDJ70231.1 - 0.0079 16.0 0.9 0.0079 16.0 0.9 2.3 2 0 0 2 2 2 1 Zinc knuckle RVP PF00077.20 CDJ70231.1 - 0.011 16.0 0.0 0.037 14.3 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_3 PF13917.6 CDJ70231.1 - 0.012 15.5 0.5 0.012 15.5 0.5 2.6 1 1 1 2 2 2 0 Zinc knuckle Asp_protease PF09668.10 CDJ70231.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_6 PF15288.6 CDJ70231.1 - 0.027 14.3 7.4 0.03 14.2 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ70231.1 - 0.071 12.9 4.5 0.77 9.5 0.3 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ70231.1 - 0.24 11.2 8.9 1.5 8.6 1.6 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF4148 PF13663.6 CDJ70232.1 - 1.5 9.1 14.4 1.8 8.8 2.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) DUF2353 PF09789.9 CDJ70233.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) CCDC24 PF15669.5 CDJ70233.1 - 0.2 11.5 5.7 0.57 10.0 5.7 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Secretin_N_2 PF07655.13 CDJ70233.1 - 0.31 11.6 14.8 0.61 10.7 14.8 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DUF4614 PF15391.6 CDJ70233.1 - 2.1 8.3 19.4 0.22 11.5 11.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 CDJ70233.1 - 2.7 6.7 13.3 0.42 9.4 9.0 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ70233.1 - 4.7 5.6 15.6 0.092 11.3 8.1 1.8 2 0 0 2 2 2 0 Macoilin family SSP160 PF06933.11 CDJ70233.1 - 5.8 5.0 16.1 8.6 4.4 16.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF2722 PF10846.8 CDJ70234.1 - 6.3e-06 25.4 5.1 6.3e-06 25.4 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ70234.1 - 0.025 13.3 14.3 0.024 13.3 14.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ70234.1 - 0.11 12.5 15.9 0.11 12.4 15.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ70234.1 - 0.65 9.6 25.1 0.77 9.3 25.1 1.1 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ70234.1 - 0.83 8.3 2.3 0.9 8.2 2.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4810 PF16068.5 CDJ70234.1 - 2.2 8.9 8.5 2.8 8.5 7.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) DUF4175 PF13779.6 CDJ70234.1 - 4.2 5.2 15.9 4.5 5.1 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pex14_N PF04695.13 CDJ70234.1 - 5.2 7.7 10.8 6.4 7.4 10.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ70234.1 - 7.5 6.4 10.9 9 6.2 10.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.8 CDJ70234.1 - 9 5.1 30.4 10 5.0 30.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Isochorismatase PF00857.20 CDJ70235.1 - 3.1e-27 95.9 1.2 2.1e-20 73.6 0.9 2.2 2 0 0 2 2 2 2 Isochorismatase family Dynein_light PF01221.18 CDJ70237.1 - 1.4e-41 140.7 0.4 1.6e-41 140.5 0.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Helicase_C PF00271.31 CDJ70238.1 - 5.8e-14 52.4 0.2 3.4e-13 49.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDJ70238.1 - 4.9e-12 45.9 0.1 5.7e-11 42.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) TFIIA PF03153.13 CDJ70238.1 - 0.018 15.1 23.9 0.022 14.7 23.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLN3 PF02487.17 CDJ70238.1 - 6 5.8 9.8 12 4.8 9.8 1.5 1 1 0 1 1 1 0 CLN3 protein ALMT PF11744.8 CDJ70238.1 - 9.3 4.9 10.4 13 4.4 10.4 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Methyltransf_25 PF13649.6 CDJ70239.1 - 3.7e-07 30.8 3.1 1.2e-05 25.9 1.1 3.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ70239.1 - 5.6e-06 26.9 1.8 0.02 15.6 0.6 3.0 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ70239.1 - 0.00043 20.1 0.3 0.00043 20.1 0.3 3.4 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ70239.1 - 0.021 15.5 0.1 0.021 15.5 0.1 3.8 3 1 0 3 3 3 0 Methyltransferase domain Nucleoside_tran PF01733.18 CDJ70239.1 - 0.11 11.9 1.2 0.2 11.0 1.2 1.3 1 0 0 1 1 1 0 Nucleoside transporter Peptidase_S64 PF08192.11 CDJ70239.1 - 0.37 9.2 16.7 0.52 8.7 16.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 CSG2 PF16965.5 CDJ70239.1 - 2.5 6.9 7.6 4.8 6.0 7.6 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator PrmA PF06325.13 CDJ70239.1 - 2.8 7.3 10.4 0.042 13.2 0.6 2.3 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) SR-25 PF10500.9 CDJ70239.1 - 3.2 7.3 23.7 1.5 8.3 20.6 2.1 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein Methyltransf_24 PF13578.6 CDJ70239.1 - 4.9 8.2 6.9 0.94 10.5 1.0 3.0 2 1 1 3 3 3 0 Methyltransferase domain Adeno_terminal PF02459.15 CDJ70239.1 - 6.6 5.0 13.2 11 4.2 13.2 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF3408 PF11888.8 CDJ70239.1 - 7.8 6.6 15.3 1.2 9.3 7.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) RCR PF12273.8 CDJ70240.1 - 0.016 15.8 2.9 0.016 15.8 2.9 6.8 6 1 0 6 6 6 0 Chitin synthesis regulation, resistance to Congo red RskA PF10099.9 CDJ70240.1 - 0.032 14.5 0.1 0.032 14.5 0.1 10.8 2 2 5 7 7 7 0 Anti-sigma-K factor rskA Semialdhyde_dhC PF02774.18 CDJ70242.1 - 0.19 11.8 0.1 0.35 10.9 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain LSM PF01423.22 CDJ70243.1 - 6.4e-20 70.6 0.0 7.7e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CDJ70243.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.5 2 0 0 2 2 2 0 RimP C-terminal SH3 domain NUDIX PF00293.28 CDJ70244.1 - 0.0014 18.7 0.0 0.0042 17.1 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain FANCF PF11107.8 CDJ70244.1 - 0.0061 15.8 1.0 0.0094 15.2 1.0 1.3 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) HydF_tetramer PF18133.1 CDJ70244.1 - 0.16 11.8 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain MRP-L46 PF11788.8 CDJ70244.1 - 1.2 9.9 8.3 8.5 7.1 7.4 2.4 1 1 1 2 2 2 0 39S mitochondrial ribosomal protein L46 SUIM_assoc PF16619.5 CDJ70244.1 - 2.4 8.3 8.6 7.8 6.6 2.1 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Prenyltrans PF00432.21 CDJ70245.1 - 8.3e-23 79.8 17.5 2.6e-09 36.6 0.0 8.3 8 1 0 8 8 8 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CDJ70245.1 - 0.041 13.0 0.0 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain MAR_sialic_bdg PF10564.9 CDJ70246.1 - 2.2e-86 284.1 29.8 1.1e-26 92.7 4.8 4.5 4 0 0 4 4 4 4 Sialic-acid binding micronemal adhesive repeat Ntox44 PF15607.6 CDJ70246.1 - 0.00044 20.5 0.1 0.69 10.3 0.0 2.9 3 0 0 3 3 3 2 Bacterial toxin 44 CagY_I PF14585.6 CDJ70246.1 - 0.042 13.9 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 CagY type 1 repeat NOG1_N PF17835.1 CDJ70248.1 - 0.00071 19.6 0.0 0.016 15.2 0.0 2.2 2 0 0 2 2 2 1 NOG1 N-terminal helical domain MAR_sialic_bdg PF10564.9 CDJ70249.1 - 1.4e-23 82.7 0.8 2.1e-23 82.2 0.8 1.3 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat E1_dh PF00676.20 CDJ70250.1 - 1.7e-82 276.8 0.0 2.1e-82 276.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 CDJ70250.1 - 3.5e-11 43.1 0.2 7.9e-11 42.0 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 CDJ70250.1 - 7.5e-05 22.1 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 CDJ70250.1 - 0.00033 19.7 0.0 0.00052 19.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Ocnus PF05005.15 CDJ70251.1 - 7.5e-22 77.5 0.3 1.4e-21 76.7 0.3 1.3 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) MukB_hinge PF16330.5 CDJ70251.1 - 0.013 15.2 0.2 0.03 14.0 0.0 1.7 2 0 0 2 2 2 0 MukB hinge domain DUF2205 PF10224.9 CDJ70252.1 - 0.0032 17.4 0.1 0.0032 17.4 0.1 2.7 3 0 0 3 3 3 1 Short coiled-coil protein AAA_13 PF13166.6 CDJ70252.1 - 0.023 13.4 13.6 0.14 10.8 9.6 2.0 2 0 0 2 2 2 0 AAA domain RadC PF04002.15 CDJ70252.1 - 0.032 14.2 1.0 0.061 13.3 0.5 1.7 2 0 0 2 2 2 0 RadC-like JAB domain Vac_Fusion PF02346.16 CDJ70252.1 - 0.077 12.6 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 Syntaxin-6_N PF09177.11 CDJ70252.1 - 0.15 12.6 11.9 3.8 8.1 1.6 3.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Tmemb_cc2 PF10267.9 CDJ70252.1 - 0.22 10.6 10.5 0.72 8.9 6.5 2.1 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Seryl_tRNA_N PF02403.22 CDJ70252.1 - 0.31 11.3 11.2 3.8 7.8 0.0 3.8 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Pol_alpha_B_N PF08418.10 CDJ70252.1 - 0.5 10.3 7.7 6.2 6.7 6.8 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF1664 PF07889.12 CDJ70252.1 - 0.79 9.8 8.0 5.9 7.0 0.0 3.5 3 2 0 3 3 3 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 CDJ70252.1 - 8 7.3 7.1 1.3 9.7 0.2 2.6 3 0 0 3 3 3 0 Occludin homology domain Wyosine_form PF08608.12 CDJ70253.1 - 9.9e-19 67.5 0.0 2.6e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CDJ70253.1 - 4.2e-14 53.3 0.0 7.8e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily CMD PF02627.20 CDJ70253.1 - 0.028 14.5 0.1 0.096 12.7 0.1 1.9 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family ELYS PF13934.6 CDJ70253.1 - 0.084 12.8 0.7 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 Nuclear pore complex assembly DNA_ligase_aden PF01653.18 CDJ70254.1 - 2.5e-39 135.2 0.0 1.3e-12 47.5 0.0 5.8 4 2 1 5 5 5 5 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 CDJ70254.1 - 3.4e-24 84.5 0.1 6.7e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain B56 PF01603.20 CDJ70255.1 - 1.4e-162 541.4 5.7 1.7e-162 541.1 5.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CDJ70255.1 - 0.2 11.5 4.6 0.17 11.8 0.5 2.8 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CAP PF00188.26 CDJ70258.1 - 4.7e-12 46.8 0.3 1.5e-11 45.3 0.3 1.9 1 0 0 1 1 1 1 Cysteine-rich secretory protein family THRAP3_BCLAF1 PF15440.6 CDJ70258.1 - 0.0011 18.1 23.7 0.0011 18.1 23.7 3.5 4 0 0 4 4 4 2 THRAP3/BCLAF1 family SR-25 PF10500.9 CDJ70259.1 - 0.0039 16.8 23.6 0.0039 16.8 23.6 3.4 3 1 0 3 3 3 2 Nuclear RNA-splicing-associated protein POX PF07526.11 CDJ70259.1 - 0.0064 17.1 4.5 0.0064 17.1 4.5 3.2 3 0 0 3 3 3 1 Associated with HOX Peptidase_S41_N PF11918.8 CDJ70259.1 - 0.0076 16.5 1.8 0.0079 16.4 0.1 1.9 2 0 0 2 2 2 1 N-terminal domain of Peptidase_S41 in eukaryotic IRBP HIGH_NTase1 PF05636.11 CDJ70259.1 - 0.025 13.8 0.9 0.041 13.1 0.9 1.3 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase ATP-synt PF00231.19 CDJ70260.1 - 7.7e-26 91.4 0.0 2.1e-24 86.7 0.0 2.3 2 0 0 2 2 2 1 ATP synthase Ribosomal_60s PF00428.19 CDJ70260.1 - 0.45 11.1 31.4 1.6 9.4 6.9 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF5529 PF17669.1 CDJ70260.1 - 4.6 7.2 12.6 0.065 13.3 4.9 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5529) NiFe-hyd_HybE PF11939.8 CDJ70260.1 - 5.8 6.8 10.5 0.92 9.4 0.1 3.0 3 0 0 3 3 3 0 [NiFe]-hydrogenase assembly, chaperone, HybE Sarcoglycan_1 PF04790.13 CDJ70260.1 - 6.4 6.0 5.2 10 5.4 5.2 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein TFIIA PF03153.13 CDJ70262.1 - 0.011 15.8 39.3 0.013 15.5 39.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L5e PF17144.4 CDJ70262.1 - 0.025 14.6 2.2 0.028 14.4 2.2 1.0 1 0 0 1 1 1 0 Ribosomal large subunit proteins 60S L5, and 50S L18 Suf PF05843.14 CDJ70262.1 - 0.1 12.6 18.1 0.12 12.4 18.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SMYLE_N PF18615.1 CDJ70262.1 - 0.17 11.5 10.7 0.19 11.3 10.7 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Peptidase_S49_N PF08496.10 CDJ70262.1 - 0.2 11.7 11.9 0.29 11.2 11.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.12 CDJ70262.1 - 0.22 10.5 16.3 0.25 10.3 16.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Dala_Dala_lig_N PF01820.21 CDJ70262.1 - 0.22 12.0 1.5 0.33 11.4 1.5 1.4 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus Spore_coat_CotO PF14153.6 CDJ70262.1 - 0.37 10.7 24.3 0.47 10.4 24.3 1.0 1 0 0 1 1 1 0 Spore coat protein CotO FAM60A PF15396.6 CDJ70262.1 - 0.39 10.7 11.1 0.45 10.5 11.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2076 PF09849.9 CDJ70262.1 - 0.63 10.0 30.4 0.77 9.7 30.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2207 PF09972.9 CDJ70262.1 - 0.87 8.3 2.1 1.1 8.0 2.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2407 PF10302.9 CDJ70262.1 - 0.9 10.1 10.2 1.2 9.7 10.2 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain DcuC PF03606.15 CDJ70262.1 - 0.99 7.8 2.0 1.2 7.5 2.0 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Med15 PF09606.10 CDJ70262.1 - 1.5 7.4 35.4 1.9 7.1 35.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2126 PF09899.9 CDJ70262.1 - 1.8 6.5 8.4 2 6.4 8.4 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PNISR PF15996.5 CDJ70262.1 - 2.1 8.6 20.4 2.9 8.1 20.4 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Hydin_ADK PF17213.3 CDJ70262.1 - 2.2 8.5 13.8 2.7 8.2 13.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MDM31_MDM32 PF08118.11 CDJ70262.1 - 2.6 6.6 9.3 3.1 6.4 9.3 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins PIP5K PF01504.18 CDJ70262.1 - 2.7 7.1 9.3 3.4 6.8 9.3 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase V_ATPase_I PF01496.19 CDJ70262.1 - 2.8 5.7 15.5 3.1 5.6 15.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gti1_Pac2 PF09729.9 CDJ70262.1 - 3.3 7.8 10.0 4.6 7.3 10.0 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family CemA PF03040.14 CDJ70262.1 - 3.7 7.4 14.4 4.5 7.2 14.4 1.0 1 0 0 1 1 1 0 CemA family DDHD PF02862.17 CDJ70262.1 - 3.7 7.6 15.2 4.6 7.3 15.2 1.1 1 0 0 1 1 1 0 DDHD domain DUF45 PF01863.17 CDJ70262.1 - 3.8 7.5 12.3 4.5 7.3 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF45 Neur_chan_memb PF02932.16 CDJ70262.1 - 3.9 7.5 11.3 4.4 7.3 11.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDFI PF15316.6 CDJ70262.1 - 3.9 7.5 10.4 5.1 7.2 10.4 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Allexi_40kDa PF05549.11 CDJ70262.1 - 4.5 6.7 9.8 5 6.6 9.8 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4569 PF15133.6 CDJ70262.1 - 4.6 6.9 16.9 5.7 6.6 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Zip PF02535.22 CDJ70262.1 - 5 6.2 6.3 5.7 6.0 6.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.9 CDJ70262.1 - 6 5.0 26.2 6.6 4.9 26.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ70262.1 - 6.7 6.4 15.9 8.1 6.2 15.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC53 PF10152.9 CDJ70262.1 - 6.8 7.1 17.9 9.4 6.6 17.9 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Band_3_cyto PF07565.13 CDJ70262.1 - 6.8 6.4 14.7 9 6.0 14.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain HCO3_cotransp PF00955.21 CDJ70262.1 - 7.1 5.3 7.0 7.4 5.3 7.0 1.0 1 0 0 1 1 1 0 HCO3- transporter family Plasmodium_Vir PF05795.11 CDJ70262.1 - 7.3 5.9 6.2 8.8 5.6 6.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SLC12 PF03522.15 CDJ70262.1 - 7.6 5.4 15.8 8.9 5.2 15.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Sin_N PF04801.13 CDJ70262.1 - 8.5 5.5 25.7 10 5.2 25.7 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Presenilin PF01080.17 CDJ70262.1 - 8.6 5.0 19.9 9.8 4.8 19.9 1.0 1 0 0 1 1 1 0 Presenilin Tristanin_u2 PF16638.5 CDJ70262.1 - 8.9 7.2 14.1 14 6.5 14.1 1.4 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers Serinc PF03348.15 CDJ70262.1 - 9.1 5.1 8.7 10 4.9 8.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Sec62 PF03839.16 CDJ70262.1 - 9.1 5.7 13.4 11 5.5 13.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CLN3 PF02487.17 CDJ70262.1 - 9.8 5.1 10.6 12 4.8 10.6 1.1 1 0 0 1 1 1 0 CLN3 protein Shikimate_dh_N PF08501.11 CDJ70263.1 - 8.2e-10 38.8 0.0 2e-08 34.4 0.0 3.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain RskA PF10099.9 CDJ70263.1 - 0.0014 19.0 14.5 0.0014 19.0 14.5 18.6 5 4 6 12 12 12 3 Anti-sigma-K factor rskA Shikimate_DH PF01488.20 CDJ70263.1 - 0.012 15.7 0.2 0.048 13.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2207 PF09972.9 CDJ70263.1 - 0.33 9.7 0.7 1.3 7.7 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) GFO_IDH_MocA PF01408.22 CDJ70263.1 - 0.49 11.2 0.0 0.49 11.2 0.0 4.9 4 0 0 4 4 4 0 Oxidoreductase family, NAD-binding Rossmann fold DUF572 PF04502.13 CDJ70264.1 - 0.0015 18.3 9.2 0.003 17.2 9.2 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF572) SUIM_assoc PF16619.5 CDJ70264.1 - 0.0048 16.9 4.3 0.0048 16.9 4.3 5.7 4 1 0 4 4 3 1 Unstructured region C-term to UIM in Ataxin3 DUF4551 PF15087.6 CDJ70264.1 - 0.011 14.7 10.6 0.018 13.9 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Dsh_C PF12316.8 CDJ70264.1 - 0.017 15.5 4.0 0.017 15.5 4.0 4.0 3 1 0 4 4 4 0 Segment polarity protein dishevelled (Dsh) C terminal Rad4 PF03835.15 CDJ70264.1 - 0.063 13.0 0.2 0.063 13.0 0.2 2.4 3 0 0 3 3 3 0 Rad4 transglutaminase-like domain DUF4407 PF14362.6 CDJ70264.1 - 0.12 11.7 15.4 0.23 10.8 15.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hamartin PF04388.12 CDJ70264.1 - 0.16 10.6 10.8 0.27 9.9 10.8 1.3 1 0 0 1 1 1 0 Hamartin protein PAT1 PF09770.9 CDJ70264.1 - 3.7 5.7 33.0 4.9 5.3 33.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.11 CDJ70264.1 - 3.9 5.9 13.4 6 5.2 13.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 Ribonuc_P_40 PF08584.11 CDJ70264.1 - 6.1 6.0 10.7 1.4 8.1 7.4 1.5 2 0 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit Dicty_REP PF05086.12 CDJ70264.1 - 6.5 4.6 5.0 9.4 4.1 5.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein IMUP PF15761.5 CDJ70264.1 - 7.5 7.3 30.3 0.26 12.0 7.0 3.8 4 0 0 4 4 4 0 Immortalisation up-regulated protein MTABC_N PF16185.5 CDJ70264.1 - 9.7 5.6 7.6 0.35 10.3 1.3 1.7 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region UPF0242 PF06785.11 CDJ70266.1 - 0.017 15.2 6.7 0.017 15.2 6.7 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TFIIA PF03153.13 CDJ70266.1 - 0.59 10.1 26.6 0.05 13.6 22.3 1.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BCL9 PF11502.8 CDJ70267.1 - 0.12 12.2 0.3 0.24 11.2 0.3 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein Exo_endo_phos PF03372.23 CDJ70269.1 - 2.8e-19 69.5 0.0 3.4e-18 66.0 0.0 2.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SARAF PF06682.12 CDJ70269.1 - 0.014 15.1 0.0 0.014 15.1 0.0 7.3 6 3 1 8 8 8 0 SOCE-associated regulatory factor of calcium homoeostasis PPP4R2 PF09184.11 CDJ70270.1 - 2.7e-08 33.8 1.8 2.7e-08 33.8 1.8 2.2 2 0 0 2 2 2 1 PPP4R2 SUIM_assoc PF16619.5 CDJ70270.1 - 0.002 18.1 0.7 0.002 18.1 0.7 4.8 4 0 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ70270.1 - 0.023 14.3 33.5 0.5 9.9 17.7 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.13 CDJ70270.1 - 0.71 8.9 40.8 1.2 8.2 22.3 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Neur_chan_memb PF02932.16 CDJ70270.1 - 0.95 9.5 24.5 0.59 10.1 4.4 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4778 PF16008.5 CDJ70270.1 - 1.4 8.9 14.4 0.34 10.9 7.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) RCR PF12273.8 CDJ70270.1 - 6.3 7.5 16.3 6.9 7.3 6.9 2.7 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red SOG2 PF10428.9 CDJ70270.1 - 9.2 5.3 37.4 3.1 6.9 11.6 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Utp14 PF04615.13 CDJ70271.1 - 0.12 11.0 35.3 0.26 9.8 35.3 1.6 1 1 0 1 1 1 0 Utp14 protein Hexokinase_2 PF03727.16 CDJ70272.1 - 6.5e-28 97.8 0.1 7.4e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 Hexokinase DUF5325 PF17259.2 CDJ70272.1 - 0.27 11.1 1.3 0.59 10.1 1.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5325) BRF1 PF07741.13 CDJ70273.1 - 0.28 11.5 0.1 0.28 11.5 0.1 3.9 3 1 0 3 3 3 0 Brf1-like TBP-binding domain SURF6 PF04935.12 CDJ70273.1 - 0.39 10.5 43.9 0.074 12.8 1.3 3.2 3 0 0 3 3 3 0 Surfeit locus protein 6 Lin-8 PF03353.15 CDJ70273.1 - 1.2 8.7 48.8 0.32 10.5 26.9 3.1 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist IHABP4_N PF16174.5 CDJ70273.1 - 2.3 8.8 56.3 0.65 10.6 2.3 3.2 3 0 0 3 3 3 0 Intracellular hyaluronan-binding protein 4 N-terminal Asparaginase_2 PF01112.18 CDJ70273.1 - 2.6 7.0 18.7 0.037 13.0 6.5 2.6 3 0 0 3 3 3 0 Asparaginase CCSAP PF15748.5 CDJ70273.1 - 5.7 7.0 57.7 5 7.2 1.7 2.3 2 1 0 2 2 2 0 Centriole, cilia and spindle-associated SLC12 PF03522.15 CDJ70276.1 - 1 8.3 6.5 1.9 7.5 6.5 1.4 1 0 0 1 1 1 0 Solute carrier family 12 RRM_1 PF00076.22 CDJ70277.1 - 0.024 14.5 0.1 0.084 12.7 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_A PF00476.20 CDJ70278.1 - 6.7e-71 239.3 0.0 4.2e-52 177.5 0.0 2.9 2 1 0 2 2 2 2 DNA polymerase family A RskA PF10099.9 CDJ70278.1 - 0.02 15.2 9.9 0.02 15.2 9.9 3.1 3 0 0 3 3 3 0 Anti-sigma-K factor rskA LRRNT PF01462.18 CDJ70278.1 - 0.042 13.5 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain TraT PF05818.12 CDJ70278.1 - 7.9 6.1 6.8 0.43 10.2 0.9 1.8 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Ribosomal_60s PF00428.19 CDJ70279.1 - 9.9 6.8 13.5 0.37 11.4 7.3 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ70280.1 - 1 9.0 10.2 1.1 8.9 10.2 1.1 1 0 0 1 1 1 0 Spt20 family MeMO_Hyd_G PF02964.16 CDJ70281.1 - 0.15 12.1 0.9 19 5.2 0.1 2.5 2 0 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain LptF_LptG PF03739.14 CDJ70282.1 - 7.1 5.4 9.0 11 4.8 9.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG HEAT_EZ PF13513.6 CDJ70283.1 - 1.2e-13 51.3 22.2 6.1e-09 36.2 0.0 13.0 11 5 3 14 14 14 5 HEAT-like repeat HEAT PF02985.22 CDJ70283.1 - 2.3e-07 30.5 22.3 0.62 10.5 0.2 9.1 9 0 0 9 9 9 3 HEAT repeat Cnd1 PF12717.7 CDJ70283.1 - 3.6e-05 23.9 0.9 0.14 12.2 0.1 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CDJ70283.1 - 4.9e-05 23.2 16.0 0.36 10.9 0.8 6.7 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat DUF4175 PF13779.6 CDJ70283.1 - 0.0015 16.5 33.1 0.0015 16.5 33.1 4.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4175) Vac14_Fab1_bd PF12755.7 CDJ70283.1 - 0.0023 18.5 0.1 0.2 12.3 0.0 3.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region TAFH PF07531.14 CDJ70283.1 - 0.0024 17.9 2.0 0.0024 17.9 2.0 5.8 5 1 1 6 6 6 1 NHR1 homology to TAF HEAT_2 PF13646.6 CDJ70283.1 - 0.092 13.2 33.3 0.97 9.9 0.9 7.2 6 3 1 7 7 7 0 HEAT repeats SpoIIE PF07228.12 CDJ70284.1 - 0.0024 17.8 0.0 0.0024 17.8 0.0 1.8 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Med3 PF11593.8 CDJ70284.1 - 5.5 6.1 20.0 7.2 5.7 20.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ADH_zinc_N PF00107.26 CDJ70285.1 - 6.5e-23 81.1 0.1 9.7e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDJ70285.1 - 5.4e-17 63.1 0.0 1.2e-16 61.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CDJ70285.1 - 0.062 12.8 0.1 0.098 12.1 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Peptidase_C97 PF05903.14 CDJ70286.1 - 3.1e-17 62.8 0.0 3.5e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4796 PF16044.5 CDJ70286.1 - 0.075 12.6 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Msg2_C PF12373.8 CDJ70286.1 - 0.093 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal EPL1 PF10513.9 CDJ70287.1 - 0.077 13.4 16.6 0.51 10.7 0.6 2.9 3 0 0 3 3 3 0 Enhancer of polycomb-like DnaB_bind PF10410.9 CDJ70287.1 - 0.09 13.0 0.1 0.6 10.3 0.1 2.5 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase DUF2722 PF10846.8 CDJ70287.1 - 0.29 10.0 48.4 0.032 13.2 8.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Rxt3 PF08642.10 CDJ70287.1 - 0.85 10.4 5.5 16 6.3 0.4 2.6 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Spt20 PF12090.8 CDJ70287.1 - 0.97 9.0 58.8 0.034 13.7 21.3 3.0 3 0 0 3 3 3 0 Spt20 family DUF4770 PF15994.5 CDJ70287.1 - 1.1 9.5 16.8 0.65 10.2 3.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Methyltransf_23 PF13489.6 CDJ70287.1 - 1.3 8.8 5.6 12 5.7 0.2 2.3 2 0 0 2 2 2 0 Methyltransferase domain Band_3_cyto PF07565.13 CDJ70287.1 - 1.6 8.5 10.8 6.5 6.5 0.8 2.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain MecA PF05389.12 CDJ70287.1 - 1.6 8.3 8.5 4.5 6.8 1.4 2.4 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) SpoIIP PF07454.11 CDJ70287.1 - 1.9 7.9 13.0 4.8 6.6 2.8 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Topoisom_I_N PF02919.15 CDJ70287.1 - 1.9 7.9 7.4 5.6 6.4 0.6 2.1 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment eIF-3_zeta PF05091.12 CDJ70287.1 - 2.6 6.9 18.4 3.7 6.4 5.3 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S49_N PF08496.10 CDJ70287.1 - 9.9 6.2 8.3 21 5.2 1.6 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CytB6-F_Fe-S PF08802.10 CDJ70288.1 - 0.0034 17.4 0.4 0.0044 17.0 0.4 1.1 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit Kinesin PF00225.23 CDJ70289.1 - 0.31 9.9 0.0 0.31 9.9 0.0 1.6 2 0 0 2 2 2 0 Kinesin motor domain DUF2722 PF10846.8 CDJ70291.1 - 0.0024 16.9 25.7 0.047 12.6 6.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) OmpH PF03938.14 CDJ70291.1 - 1.3 9.4 50.9 1.1 9.6 26.4 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SelP_N PF04592.14 CDJ70291.1 - 2.9 7.2 19.0 0.032 13.6 2.6 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Presenilin PF01080.17 CDJ70291.1 - 3.4 6.3 21.8 2 7.1 6.0 2.1 2 0 0 2 2 2 0 Presenilin CDC27 PF09507.10 CDJ70292.1 - 2.5 7.4 13.4 3.1 7.1 13.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Exonuc_VII_L PF02601.15 CDJ70293.1 - 0.051 13.1 10.5 0.063 12.8 10.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Macoilin PF09726.9 CDJ70293.1 - 0.19 10.2 28.8 0.27 9.8 28.8 1.2 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CDJ70293.1 - 0.59 10.1 44.4 0.74 9.7 44.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 CDJ70294.1 - 3e-07 29.7 9.7 3.8e-07 29.4 9.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CDJ70294.1 - 0.039 12.2 2.3 0.24 9.6 1.5 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF5518 PF17647.1 CDJ70294.1 - 1.2 9.3 21.0 0.079 13.1 12.7 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5518) DUF4149 PF13664.6 CDJ70295.1 - 0.031 14.6 4.1 0.053 13.9 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Sulf_transp PF04143.14 CDJ70295.1 - 0.045 13.3 2.2 0.055 13.0 2.2 1.2 1 0 0 1 1 1 0 Sulphur transport Frag1 PF10277.9 CDJ70295.1 - 0.081 12.4 0.2 0.11 12.0 0.2 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family TFIIA PF03153.13 CDJ70295.1 - 0.088 12.8 6.2 0.096 12.7 6.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MASE4 PF17158.4 CDJ70295.1 - 0.098 11.9 1.0 1.3 8.2 0.0 2.0 1 1 1 2 2 2 0 Membrane-associated sensor, integral membrane domain Yip1 PF04893.17 CDJ70295.1 - 0.11 12.3 5.5 2.2 8.0 5.3 2.1 1 1 0 1 1 1 0 Yip1 domain DUF1345 PF07077.11 CDJ70295.1 - 0.29 10.8 2.6 0.38 10.4 0.2 1.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1345) DUF1772 PF08592.11 CDJ70295.1 - 2.5 8.4 15.0 36 4.6 15.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Trp_oprn_chp PF09534.10 CDJ70295.1 - 9.7 5.9 21.5 36 4.1 21.5 1.8 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Glycos_transf_2 PF00535.26 CDJ70296.1 - 3.2e-21 75.9 0.0 5.1e-21 75.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ70296.1 - 4.8e-11 43.0 0.1 4.8e-11 43.0 0.1 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDJ70296.1 - 6.5e-06 25.7 1.5 1.1e-05 25.0 0.1 1.9 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 CDJ70296.1 - 0.0086 16.0 0.1 0.32 10.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 CDtoxinA PF03498.14 CDJ70296.1 - 0.15 11.7 0.1 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain TFIIA PF03153.13 CDJ70296.1 - 0.49 10.3 8.7 0.21 11.5 4.4 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ70297.1 - 0.0029 17.9 2.0 0.0029 17.9 2.0 9.9 3 2 4 8 8 8 2 Anti-sigma-K factor rskA CAP_GLY PF01302.25 CDJ70298.1 - 1.1e-10 41.4 0.0 1.7e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 CAP-Gly domain RskA PF10099.9 CDJ70298.1 - 9.7e-08 32.5 6.2 0.00088 19.6 1.7 2.2 1 1 1 2 2 2 2 Anti-sigma-K factor rskA RAB3GAP2_N PF14655.6 CDJ70298.1 - 0.00031 20.1 5.8 0.00045 19.6 0.4 2.1 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIA PF03153.13 CDJ70298.1 - 0.0038 17.3 2.6 0.0038 17.3 2.6 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit RP853 PF17542.2 CDJ70298.1 - 0.2 10.7 0.6 0.28 10.3 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized RP853 DUF4834 PF16118.5 CDJ70298.1 - 0.57 11.2 12.4 1.6 9.7 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ70298.1 - 1.7 8.2 35.6 0.18 11.4 10.7 2.2 2 0 0 2 2 2 0 Spt20 family Med15 PF09606.10 CDJ70298.1 - 3.9 6.1 29.2 0.2 10.3 9.1 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Shadoo PF14999.6 CDJ70298.1 - 6.2 6.9 19.5 0.55 10.3 2.8 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Adeno_PIX PF03955.14 CDJ70298.1 - 8.1 6.7 12.6 4.7 7.4 1.3 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Ribosomal_60s PF00428.19 CDJ70298.1 - 8.9 7.0 30.7 7.1 7.3 7.7 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein 5_3_exonuc_N PF02739.16 CDJ70299.1 - 1.3e-18 67.4 0.0 1.8e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain SUIM_assoc PF16619.5 CDJ70299.1 - 0.079 13.0 9.8 0.27 11.3 9.8 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 GLTT PF01744.20 CDJ70299.1 - 0.4 10.5 31.0 4.4 7.2 0.8 5.8 3 2 1 5 5 5 0 GLTT repeat (6 copies) V_ATPase_I PF01496.19 CDJ70300.1 - 6.9 4.5 11.3 8.9 4.1 11.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med15 PF09606.10 CDJ70300.1 - 9.7 4.7 47.8 15 4.1 47.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SUIM_assoc PF16619.5 CDJ70301.1 - 5.6e-05 23.1 1.8 5.6e-05 23.1 1.8 2.8 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ70301.1 - 0.00097 18.2 0.5 0.00097 18.2 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ70301.1 - 0.0016 18.5 0.3 0.0016 18.5 0.3 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF4667 PF15700.5 CDJ70301.1 - 0.0034 17.5 0.2 0.0052 16.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) RskA PF10099.9 CDJ70301.1 - 0.0045 17.3 22.2 0.16 12.2 3.7 2.4 2 0 0 2 2 2 2 Anti-sigma-K factor rskA PQQ_3 PF13570.6 CDJ70301.1 - 0.005 17.3 5.4 0.021 15.3 0.1 3.8 3 1 0 3 3 3 1 PQQ-like domain Inhibitor_I36 PF03995.13 CDJ70301.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor family I36 DUF3446 PF11928.8 CDJ70301.1 - 0.75 10.1 13.6 0.12 12.7 5.0 2.9 3 0 0 3 3 3 0 Early growth response N-terminal domain Rib_recp_KP_reg PF05104.12 CDJ70303.1 - 0.95 10.5 14.8 1.3 10.1 14.8 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region DUF4614 PF15391.6 CDJ70303.1 - 1.3 9.0 22.2 1.8 8.5 22.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 CDJ70303.1 - 1.6 7.5 12.2 1.5 7.6 12.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF966 PF06136.13 CDJ70303.1 - 9.7 5.8 18.5 11 5.6 18.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Caldesmon PF02029.15 CDJ70304.1 - 0.00074 18.4 8.6 0.00074 18.4 8.6 3.7 3 1 0 3 3 3 2 Caldesmon RabGAP-TBC PF00566.18 CDJ70305.1 - 2.5e-38 131.9 0.9 8.7e-38 130.1 0.9 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Apt1 PF10351.9 CDJ70305.1 - 0.0095 14.8 1.5 0.067 12.0 0.1 1.9 2 0 0 2 2 2 1 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ70305.1 - 0.085 12.5 32.8 0.46 10.1 5.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF913 PF06025.12 CDJ70305.1 - 0.22 10.4 4.4 0.089 11.8 1.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF755 PF05501.11 CDJ70305.1 - 0.36 11.1 33.2 1.1 9.6 7.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) CCSAP PF15748.5 CDJ70305.1 - 0.45 10.6 11.2 3.2 7.9 0.8 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF4692 PF15763.5 CDJ70305.1 - 0.93 9.9 14.4 0.81 10.1 0.4 2.2 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Lin-8 PF03353.15 CDJ70305.1 - 2.2 7.8 11.7 0.65 9.5 5.3 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Kinesin_assoc PF16183.5 CDJ70305.1 - 4.2 7.5 5.2 10 6.2 1.8 2.3 2 0 0 2 2 2 0 Kinesin-associated SR-25 PF10500.9 CDJ70306.1 - 0.0014 18.3 13.5 0.0015 18.2 13.5 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ70306.1 - 0.19 11.9 16.3 0.21 11.7 16.3 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Spt20 PF12090.8 CDJ70306.1 - 0.21 11.2 25.6 0.25 10.9 25.6 1.2 1 0 0 1 1 1 0 Spt20 family Peptidase_C58 PF03543.14 CDJ70306.1 - 0.28 10.9 12.9 0.27 10.9 12.9 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen THRAP3_BCLAF1 PF15440.6 CDJ70306.1 - 0.29 10.1 16.0 0.32 9.9 16.0 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family STAC2_u1 PF16664.5 CDJ70306.1 - 0.81 10.1 14.0 1 9.8 14.0 1.0 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Pox_A11 PF05061.13 CDJ70306.1 - 1.4 8.1 4.9 1.6 7.9 4.9 1.0 1 0 0 1 1 1 0 Poxvirus A11 Protein Pex14_N PF04695.13 CDJ70306.1 - 1.9 9.1 20.0 2 9.1 20.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ70306.1 - 2.6 7.9 17.3 2.6 8.0 17.3 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CCDC53 PF10152.9 CDJ70306.1 - 4 7.9 13.2 4.5 7.7 13.2 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex IMUP PF15761.5 CDJ70306.1 - 4.5 8.0 13.4 6.6 7.5 13.4 1.4 1 1 0 1 1 1 0 Immortalisation up-regulated protein Roughex PF06020.11 CDJ70306.1 - 5.4 6.0 12.6 5.6 6.0 12.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein EIIBC-GUT_N PF03612.14 CDJ70306.1 - 5.5 6.7 9.5 5.4 6.7 9.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4407 PF14362.6 CDJ70306.1 - 7.1 5.9 13.9 7.4 5.8 13.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TERB2 PF15101.6 CDJ70306.1 - 7.6 6.5 16.7 9.2 6.3 16.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NDK PF00334.19 CDJ70307.1 - 6.1e-35 120.2 0.0 6.8e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 CDJ70307.1 - 0.031 14.8 0.0 0.046 14.2 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ PAT1 PF09770.9 CDJ70308.1 - 0.15 10.3 31.4 0.18 10.1 31.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Caldesmon PF02029.15 CDJ70308.1 - 0.17 10.6 19.8 0.22 10.3 19.8 1.0 1 0 0 1 1 1 0 Caldesmon Lipase_GDSL_3 PF14606.6 CDJ70308.1 - 0.47 10.6 5.7 0.81 9.8 5.6 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MtaB PF12176.8 CDJ70308.1 - 0.53 9.0 4.3 0.69 8.6 4.3 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit SLC12 PF03522.15 CDJ70308.1 - 0.76 8.7 15.3 0.85 8.6 15.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 EBP50_C PF09007.11 CDJ70308.1 - 1.8 9.6 13.9 2.6 9.1 13.6 1.4 1 1 0 1 1 1 0 EBP50, C-terminal PXA PF02194.15 CDJ70308.1 - 2.2 8.2 10.0 3.5 7.6 10.0 1.3 1 0 0 1 1 1 0 PXA domain Presenilin PF01080.17 CDJ70308.1 - 3 6.5 15.6 3.8 6.2 15.6 1.2 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 CDJ70308.1 - 5.1 6.8 15.9 7.3 6.3 15.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PIN_12 PF16289.5 CDJ70308.1 - 5.1 7.5 7.0 7.2 7.1 7.0 1.2 1 0 0 1 1 1 0 PIN domain CCSAP PF15748.5 CDJ70308.1 - 8.3 6.5 18.4 11 6.1 18.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Radial_spoke_3 PF06098.11 CDJ70309.1 - 1.3e-44 152.6 4.6 1.3e-44 152.6 4.6 3.5 3 1 0 3 3 3 1 Radial spoke protein 3 TAXi_C PF14541.6 CDJ70309.1 - 9.5e-18 64.5 0.0 2.2e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 CDJ70309.1 - 1.1e-13 51.3 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ70309.1 - 9.7e-08 32.4 0.9 9.7e-08 32.4 0.9 2.5 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal RskA PF10099.9 CDJ70309.1 - 0.00085 19.7 0.0 0.00085 19.7 0.0 5.6 3 2 1 4 4 4 2 Anti-sigma-K factor rskA LAB_N PF07578.11 CDJ70309.1 - 0.15 12.1 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain Ribosomal_60s PF00428.19 CDJ70310.1 - 8.2e-05 23.1 9.4 0.00016 22.2 9.4 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4228 PF14009.6 CDJ70310.1 - 1.5 9.2 14.1 1.6 9.1 7.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) SR-25 PF10500.9 CDJ70312.1 - 0.0011 18.6 11.9 0.0011 18.6 11.9 4.1 2 1 2 4 4 4 2 Nuclear RNA-splicing-associated protein Surface_antigen PF11054.8 CDJ70313.1 - 3.7e-26 92.3 2.6 5.3e-26 91.8 2.6 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ70314.1 - 2.7e-33 115.7 2.5 3.9e-33 115.2 2.5 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Imm74 PF15603.6 CDJ70314.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 74 Surface_antigen PF11054.8 CDJ70315.1 - 9.7e-33 113.8 1.4 1.3e-32 113.4 1.4 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ70316.1 - 1.2e-33 116.8 0.8 1.6e-33 116.4 0.8 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Spt20 PF12090.8 CDJ70318.1 - 0.0057 16.3 6.8 0.0057 16.3 6.8 4.2 4 1 1 5 5 5 2 Spt20 family SUIM_assoc PF16619.5 CDJ70318.1 - 5.3 7.2 55.2 0.056 13.5 12.2 4.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Clathrin PF00637.20 CDJ70321.1 - 8.6e-170 557.4 20.9 4.9e-29 101.1 0.3 7.6 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CDJ70321.1 - 3.5e-27 94.1 0.4 2.8e-26 91.2 0.1 2.7 2 0 0 2 2 2 1 Clathrin-H-link Coatomer_WDAD PF04053.14 CDJ70321.1 - 5.6e-09 35.6 1.0 0.18 10.8 0.0 4.2 4 0 0 4 4 4 3 Coatomer WD associated region Clathrin_propel PF01394.20 CDJ70321.1 - 7.7e-08 32.3 0.0 5.5e-05 23.3 0.0 4.2 4 0 0 4 4 4 1 Clathrin propeller repeat TPR_19 PF14559.6 CDJ70321.1 - 0.045 14.3 7.8 0.76 10.3 0.4 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ70321.1 - 0.12 12.8 0.1 17 6.1 0.0 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 CDJ70321.1 - 0.24 11.5 1.6 0.35 10.9 0.1 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TPR_1 PF00515.28 CDJ70321.1 - 0.26 11.2 8.4 30 4.6 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ70321.1 - 0.29 11.4 16.9 1.9 8.8 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ70321.1 - 0.66 10.8 3.5 5.1 8.0 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ70321.1 - 2.3 9.3 22.2 21 6.3 0.0 10.2 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ70321.1 - 7 7.5 9.5 6.6e+02 1.3 0.0 6.7 6 1 1 7 7 7 0 Tetratricopeptide repeat Sugar_tr PF00083.24 CDJ70323.1 - 1.8e-83 280.9 25.3 2.1e-83 280.7 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ70323.1 - 1.3e-35 123.0 53.3 1.3e-26 93.4 30.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDJ70323.1 - 0.0019 16.6 4.6 0.0019 16.6 4.6 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Holin_SPP1 PF04688.13 CDJ70323.1 - 2 8.6 6.0 3.1 8.0 0.7 3.2 2 0 0 2 2 2 0 SPP1 phage holin Frataxin_Cyay PF01491.16 CDJ70324.1 - 2.9e-22 78.8 0.0 4.2e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain SRP9-21 PF05486.12 CDJ70325.1 - 3.1e-05 24.3 0.1 0.0005 20.4 0.1 2.1 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Patatin PF01734.22 CDJ70327.1 - 2.9e-06 27.6 0.3 0.00012 22.4 2.1 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase DUF1205 PF06722.12 CDJ70327.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) ATG7_N PF16420.5 CDJ70328.1 - 1.3e-21 77.6 10.9 7.4e-14 52.1 0.0 3.2 4 0 0 4 4 4 2 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CDJ70328.1 - 1.3e-13 50.9 0.0 5.8e-13 48.8 0.0 2.0 2 1 0 2 2 2 1 ThiF family OTU PF02338.19 CDJ70329.1 - 2.2e-15 57.3 0.0 4.1e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDJ70329.1 - 0.028 13.9 0.0 3.1 7.2 0.0 2.2 1 1 0 2 2 2 0 Peptidase C65 Otubain Mito_carr PF00153.27 CDJ70332.1 - 1.3e-55 185.3 0.2 1.3e-18 66.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DNA_pol_B PF00136.21 CDJ70333.1 - 3.2e-138 461.3 0.5 4.2e-138 460.9 0.5 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CDJ70333.1 - 8.4e-74 248.7 0.0 1.4e-73 248.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CDJ70333.1 - 3.4e-17 62.7 5.9 1e-16 61.2 5.9 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CDJ70333.1 - 0.011 14.6 0.1 0.089 11.6 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 CDJ70333.1 - 0.073 12.7 0.0 0.17 11.6 0.0 1.5 1 1 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB AAA_2 PF07724.14 CDJ70334.1 - 3.4e-24 85.9 0.1 4.3e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CDJ70334.1 - 2.1e-05 25.0 0.0 3.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDJ70334.1 - 0.0023 17.9 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CDJ70335.1 - 2.1e-07 31.4 0.0 3.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ70335.1 - 1.4e-06 28.4 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDJ70335.1 - 1.9e-06 28.1 0.0 3.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ70335.1 - 8.2e-06 26.1 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CDJ70335.1 - 9.7e-06 25.0 0.2 1.4e-05 24.5 0.2 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 CDJ70335.1 - 1.9e-05 25.1 0.1 3.3e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain MCM PF00493.23 CDJ70335.1 - 1.9e-05 23.9 0.0 2.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_18 PF13238.6 CDJ70335.1 - 6.2e-05 23.6 0.0 0.0001 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDJ70335.1 - 0.00052 19.5 0.1 0.008 15.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CDJ70335.1 - 0.0017 18.5 0.1 0.0045 17.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 CDJ70335.1 - 0.0019 18.5 0.0 0.0031 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ70335.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 CDJ70335.1 - 0.0024 17.2 0.1 0.0048 16.2 0.1 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_3 PF07726.11 CDJ70335.1 - 0.0033 17.3 0.1 0.13 12.2 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ70335.1 - 0.0039 16.9 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 CDJ70335.1 - 0.0044 16.6 0.0 0.0064 16.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 CDJ70335.1 - 0.0061 16.6 0.0 0.009 16.0 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 CDJ70335.1 - 0.008 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 CDJ70335.1 - 0.0095 15.7 0.0 0.021 14.6 0.0 1.5 1 1 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.6 CDJ70335.1 - 0.012 16.0 0.1 0.021 15.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDJ70335.1 - 0.023 14.4 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 CDJ70335.1 - 0.027 14.6 0.1 0.079 13.1 0.0 1.8 2 1 0 2 2 1 0 Shikimate kinase RsgA_GTPase PF03193.16 CDJ70335.1 - 0.038 13.9 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 CDJ70335.1 - 0.041 14.3 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IPT PF01745.16 CDJ70335.1 - 0.043 13.2 0.0 0.076 12.4 0.0 1.5 1 1 0 1 1 1 0 Isopentenyl transferase TniB PF05621.11 CDJ70335.1 - 0.046 13.1 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NTPase_1 PF03266.15 CDJ70335.1 - 0.054 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 NTPase SRP54 PF00448.22 CDJ70335.1 - 0.055 13.1 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.15 CDJ70335.1 - 0.058 13.4 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 CDJ70335.1 - 0.065 12.3 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CPT PF07931.12 CDJ70335.1 - 0.069 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_6 PF12774.7 CDJ70335.1 - 0.098 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PduV-EutP PF10662.9 CDJ70335.1 - 0.099 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 CDJ70335.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CDJ70335.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 CDJ70335.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 dNK PF01712.19 CDJ70335.1 - 0.19 11.5 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase CLAMP PF14769.6 CDJ70336.1 - 6.2e-17 61.9 0.6 1.2e-16 61.0 0.6 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Pro_isomerase PF00160.21 CDJ70337.1 - 1.9e-34 119.2 0.0 1.7e-33 116.1 0.0 1.9 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RskA PF10099.9 CDJ70337.1 - 0.95 9.7 5.2 0.72 10.1 2.9 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA PTH2 PF01981.16 CDJ70338.1 - 0.46 10.8 1.7 1.1 9.6 1.7 1.6 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 BRO1 PF03097.18 CDJ70339.1 - 8.5e-13 47.9 0.1 8.5e-13 47.9 0.1 3.4 4 0 0 4 4 4 1 BRO1-like domain DUF2573 PF10835.8 CDJ70339.1 - 0.0052 17.1 2.2 0.18 12.2 0.1 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF2573) PMC2NT PF08066.12 CDJ70339.1 - 0.0097 16.6 0.5 0.0097 16.6 0.5 4.0 4 1 1 5 5 5 1 PMC2NT (NUC016) domain Maf1 PF09174.10 CDJ70342.1 - 3.8e-26 92.3 0.0 1.4e-21 77.4 0.0 2.1 2 0 0 2 2 2 2 Maf1 regulator HSP90 PF00183.18 CDJ70343.1 - 1.2e-128 430.2 23.6 1.2e-122 410.4 22.2 4.2 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CDJ70343.1 - 1.1e-08 35.0 3.2 1.1e-08 35.0 3.2 2.2 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ70343.1 - 5.2e-08 33.4 0.0 1.4e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ESM4 PF15952.5 CDJ70343.1 - 0.47 10.9 33.9 1.9 8.9 7.7 2.6 2 0 0 2 2 2 0 Enhancer of split M4 family DUF2722 PF10846.8 CDJ70343.1 - 0.63 8.9 50.1 0.017 14.1 1.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ70343.1 - 1.1 8.8 54.8 2.3 7.7 12.5 3.4 3 0 0 3 3 3 0 Spt20 family PGK PF00162.19 CDJ70344.1 - 5.7e-44 150.6 0.2 7.4e-44 150.2 0.2 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3138 PF11336.8 CDJ70344.1 - 0.0015 17.2 8.8 0.0015 17.2 8.8 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3138) RskA PF10099.9 CDJ70344.1 - 0.0021 18.4 15.2 0.0021 18.4 15.2 2.2 2 1 0 2 2 2 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ70344.1 - 0.027 13.5 6.6 0.048 12.6 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Adeno_PV PF03910.13 CDJ70344.1 - 1.4 7.6 7.2 2.1 6.9 7.2 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV TFIIA PF03153.13 CDJ70344.1 - 1.6 8.6 26.0 2.8 7.9 26.1 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3995 PF13160.6 CDJ70344.1 - 4.6 7.6 10.3 0.058 13.7 1.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) Spt20 PF12090.8 CDJ70344.1 - 6.5 6.3 20.2 3.3 7.2 15.2 2.1 2 0 0 2 2 2 0 Spt20 family Bestrophin PF01062.21 CDJ70345.1 - 3.2e-05 23.5 2.5 5.8e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel SR-25 PF10500.9 CDJ70345.1 - 0.00022 20.9 43.4 0.00022 20.9 43.4 5.3 2 2 2 4 4 4 2 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ70345.1 - 0.0039 17.2 1.0 0.0039 17.2 1.0 5.8 4 1 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 SRC-1 PF08832.10 CDJ70345.1 - 3.7 8.7 0.0 3.7 8.7 0.0 6.1 5 1 2 7 7 7 0 Steroid receptor coactivator Glycos_transf_2 PF00535.26 CDJ70346.1 - 6.8e-06 26.0 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 SR-25 PF10500.9 CDJ70346.1 - 2.4 7.7 8.4 3.9 7.0 8.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PGM_PMM_III PF02880.16 CDJ70347.1 - 8.7e-26 90.4 0.0 1.9e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 CDJ70347.1 - 3e-10 40.0 0.0 5.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CDJ70347.1 - 3.5e-10 40.4 0.0 1e-09 38.9 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CDJ70347.1 - 0.0054 16.9 0.0 0.023 14.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Arf PF00025.21 CDJ70348.1 - 7.4e-76 253.5 0.0 8.6e-76 253.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDJ70348.1 - 2.4e-14 53.6 0.0 3.3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ70348.1 - 1.4e-13 50.7 0.0 1.7e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDJ70348.1 - 2.4e-12 46.7 1.1 2.2e-08 33.7 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CDJ70348.1 - 3.9e-12 46.1 0.0 4.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CDJ70348.1 - 3.2e-09 36.5 0.0 3.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ70348.1 - 2.5e-05 24.3 0.0 4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CDJ70348.1 - 0.013 14.8 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase COX2 PF00116.20 CDJ70349.1 - 4.5e-43 146.0 0.0 6.2e-43 145.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain CS PF04969.16 CDJ70350.1 - 7.8e-07 30.0 0.0 0.00014 22.8 0.0 3.0 2 1 0 2 2 2 1 CS domain SR-25 PF10500.9 CDJ70350.1 - 0.0045 16.6 1.9 0.0045 16.6 1.9 3.6 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein UPF0231 PF06062.11 CDJ70350.1 - 0.02 15.2 0.1 0.052 13.8 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) GYF_2 PF14237.6 CDJ70350.1 - 0.024 14.4 0.1 0.39 10.6 0.0 2.7 3 0 0 3 3 3 0 GYF domain 2 CDC37_N PF03234.14 CDJ70350.1 - 0.072 14.0 0.6 0.072 14.0 0.6 4.1 4 1 0 4 4 4 0 Cdc37 N terminal kinase binding DUF2164 PF09932.9 CDJ70350.1 - 0.17 12.0 1.8 0.34 11.0 1.8 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) SUZ PF12752.7 CDJ70350.1 - 1.5 9.7 16.2 3 8.7 2.9 3.6 3 0 0 3 3 3 0 SUZ domain Secretin_N_2 PF07655.13 CDJ70350.1 - 4 8.0 32.7 2 9.0 1.0 3.5 3 0 0 3 3 3 0 Secretin N-terminal domain PIG-L PF02585.17 CDJ70351.1 - 1.3e-19 71.1 1.5 1.3e-18 67.9 0.0 2.7 1 1 1 2 2 2 1 GlcNAc-PI de-N-acetylase RskA PF10099.9 CDJ70351.1 - 5.3e-05 23.6 0.6 0.039 14.2 2.0 2.9 2 2 0 2 2 2 1 Anti-sigma-K factor rskA DUF4207 PF13904.6 CDJ70351.1 - 0.00031 20.5 12.8 0.00031 20.5 12.8 3.6 3 1 0 3 3 2 1 Domain of unknown function (DUF4207) Adaptin_binding PF10199.9 CDJ70351.1 - 0.0023 18.5 10.0 0.64 10.6 0.1 2.4 2 0 0 2 2 2 2 Alpha and gamma adaptin binding protein p34 DUF1631 PF07793.11 CDJ70351.1 - 0.0045 15.5 25.4 0.0095 14.4 10.4 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1631) Presenilin PF01080.17 CDJ70351.1 - 0.012 14.4 21.3 0.027 13.2 0.9 2.2 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 CDJ70351.1 - 0.017 15.2 8.1 1.4 9.0 0.2 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 CDJ70351.1 - 0.021 14.3 16.0 0.19 11.2 6.3 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Spt20 PF12090.8 CDJ70351.1 - 0.026 14.1 42.4 0.062 12.9 12.6 2.3 2 0 0 2 2 2 0 Spt20 family SPX PF03105.19 CDJ70351.1 - 0.061 13.2 0.0 0.061 13.2 0.0 2.9 2 1 1 3 3 1 0 SPX domain Afi1 PF07792.12 CDJ70351.1 - 0.062 13.8 14.3 1.6 9.2 0.7 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking EPL1 PF10513.9 CDJ70351.1 - 0.081 13.3 15.0 0.58 10.5 6.4 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like Nucleoside_tran PF01733.18 CDJ70351.1 - 0.11 11.9 1.8 1 8.7 0.6 2.3 2 0 0 2 2 2 0 Nucleoside transporter PIP5K PF01504.18 CDJ70351.1 - 0.14 11.4 10.7 0.55 9.4 4.6 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase CNDH2_C PF16858.5 CDJ70351.1 - 0.22 11.3 19.2 0.43 10.4 7.3 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2052 PF09747.9 CDJ70351.1 - 0.36 10.9 23.1 0.73 9.9 3.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) AAA_11 PF13086.6 CDJ70351.1 - 0.4 10.4 15.1 4.7 6.9 9.1 2.2 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 CDJ70351.1 - 0.42 10.1 12.4 1.6 8.2 0.7 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Pex14_N PF04695.13 CDJ70351.1 - 0.51 11.0 26.2 6.9 7.3 8.0 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SLC12 PF03522.15 CDJ70351.1 - 0.58 9.1 15.4 1.1 8.3 7.1 2.2 2 0 0 2 2 2 0 Solute carrier family 12 DUF2370 PF10176.9 CDJ70351.1 - 0.65 9.6 2.9 26 4.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) RR_TM4-6 PF06459.12 CDJ70351.1 - 0.7 9.7 22.4 0.26 11.1 8.9 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Peptidase_S15 PF02129.18 CDJ70351.1 - 0.89 9.1 6.3 4.6 6.8 0.0 2.4 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2151 PF10221.9 CDJ70351.1 - 0.92 8.0 9.8 0.066 11.8 2.3 2.0 2 0 0 2 2 2 0 Cell cycle and development regulator Connexin PF00029.19 CDJ70351.1 - 1.8 8.2 17.8 1.4 8.6 0.2 2.8 3 0 0 3 3 2 0 Connexin Pinin_SDK_memA PF04696.13 CDJ70351.1 - 2.1 8.4 44.6 0.66 10.0 12.2 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region PepSY_TM PF03929.16 CDJ70351.1 - 2.3 7.8 3.9 21 4.7 0.0 2.6 3 0 0 3 3 2 0 PepSY-associated TM region CPSF100_C PF13299.6 CDJ70351.1 - 2.6 8.2 15.1 1.5 9.0 5.0 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Otopetrin PF03189.13 CDJ70351.1 - 3.2 6.5 6.6 2.3 6.9 0.1 2.2 2 0 0 2 2 2 0 Otopetrin Tim54 PF11711.8 CDJ70351.1 - 3.3 6.4 17.9 2.3 6.9 7.6 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FYDLN_acid PF09538.10 CDJ70351.1 - 5.4 7.8 17.8 13 6.5 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DDRGK PF09756.9 CDJ70351.1 - 5.8 6.5 39.2 0.21 11.2 17.1 2.2 2 0 0 2 2 2 0 DDRGK domain PA26 PF04636.13 CDJ70351.1 - 6.3 5.6 14.2 1.3 7.8 0.6 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Zip PF02535.22 CDJ70351.1 - 6.6 5.9 12.0 0.22 10.7 0.4 2.6 3 0 0 3 3 2 0 ZIP Zinc transporter CLN3 PF02487.17 CDJ70351.1 - 7.6 5.5 13.6 12 4.8 0.1 2.3 2 0 0 2 2 2 0 CLN3 protein DUF1980 PF09323.10 CDJ70351.1 - 7.7 6.4 10.7 16 5.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4746 PF15928.5 CDJ70351.1 - 7.9 5.8 22.9 3.9 6.8 11.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Nop25 PF09805.9 CDJ70351.1 - 8.5 6.9 27.7 10 6.6 13.2 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) V_ATPase_I PF01496.19 CDJ70351.1 - 8.9 4.1 20.3 1.2 6.9 0.5 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 CDJ70351.1 - 9.3 5.9 16.5 11 5.6 0.6 2.6 2 0 0 2 2 2 0 FAM176 family BCAS2 PF05700.11 CDJ70353.1 - 3.6e-43 147.7 7.2 5.4e-43 147.1 7.2 1.3 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) MitoNEET_N PF10660.9 CDJ70353.1 - 0.26 11.3 0.4 0.68 10.0 0.4 1.7 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Ribosomal_L16 PF00252.18 CDJ70354.1 - 1.9e-41 141.1 0.0 2.3e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Roughex PF06020.11 CDJ70355.1 - 7.5 5.5 8.1 0.41 9.7 1.9 1.9 2 0 0 2 2 2 0 Drosophila roughex protein Peptidase_M20 PF01546.28 CDJ70356.1 - 1.1e-28 100.3 0.3 3.6e-28 98.7 0.0 2.0 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDJ70356.1 - 7.6e-11 41.9 0.6 2.1e-10 40.5 0.0 2.1 2 1 0 2 2 2 1 Peptidase dimerisation domain Pkinase PF00069.25 CDJ70357.1 - 4.1e-45 154.2 0.0 1.2e-44 152.7 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ70357.1 - 2.1e-20 73.1 0.0 4.8e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CDJ70357.1 - 0.0064 16.1 1.7 0.0084 15.7 0.0 2.0 2 0 0 2 2 2 1 RIO1 family DLIC PF05783.11 CDJ70358.1 - 1.4 7.7 4.0 1.3 7.7 4.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Rotamase_2 PF13145.6 CDJ70358.1 - 7.4 7.4 16.0 9.7 7.1 16.0 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain Macoilin PF09726.9 CDJ70359.1 - 0.0018 16.9 22.6 0.0018 16.9 22.6 3.6 1 1 2 3 3 3 1 Macoilin family TFIIA PF03153.13 CDJ70360.1 - 0.45 10.5 8.5 0.88 9.5 8.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC_trans_aux PF03886.13 CDJ70361.1 - 0.011 15.3 2.0 0.018 14.6 2.0 1.4 1 0 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component TPR_16 PF13432.6 CDJ70362.1 - 0.00057 20.5 7.2 0.00057 20.5 7.2 10.6 10 2 1 11 11 11 1 Tetratricopeptide repeat TFIIA PF03153.13 CDJ70362.1 - 0.0025 17.9 28.3 0.0025 17.9 28.3 3.8 3 1 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Otopetrin PF03189.13 CDJ70362.1 - 0.015 14.2 2.5 0.03 13.1 0.0 2.7 2 1 0 3 3 3 0 Otopetrin TPR_2 PF07719.17 CDJ70362.1 - 0.051 13.7 9.1 0.39 11.0 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SID-1_RNA_chan PF13965.6 CDJ70362.1 - 1.3 7.4 8.4 0.8 8.0 1.6 2.4 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 SUIM_assoc PF16619.5 CDJ70363.1 - 3.2e-08 33.5 46.8 7.3e-05 22.7 0.0 5.8 3 2 1 4 4 4 3 Unstructured region C-term to UIM in Ataxin3 ABC_tran_Xtn PF12848.7 CDJ70363.1 - 0.0068 16.4 0.9 0.0068 16.4 0.9 5.0 4 2 2 6 6 6 1 ABC transporter UPF0564 PF10595.9 CDJ70363.1 - 1.5 7.8 25.1 0.086 11.9 6.8 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0564 SPX PF03105.19 CDJ70364.1 - 0.00049 20.1 10.8 0.00049 20.1 10.8 4.8 4 1 1 5 5 5 1 SPX domain CAF1C_H4-bd PF12265.8 CDJ70365.1 - 4.1e-16 59.0 0.1 1.1e-15 57.7 0.0 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex EBP50_C PF09007.11 CDJ70365.1 - 0.072 14.1 7.7 0.61 11.1 3.8 2.7 2 0 0 2 2 2 0 EBP50, C-terminal Alkyl_sulf_dimr PF14863.6 CDJ70366.1 - 4.2e-29 101.8 1.5 4.2e-29 101.8 1.5 3.9 4 1 1 5 5 4 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 CDJ70366.1 - 4.7e-06 26.8 0.0 0.069 13.2 0.0 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 CDJ70366.1 - 0.00037 20.8 0.4 1.7 8.9 0.0 3.5 3 0 0 3 3 3 2 Alkyl sulfatase C-terminal Pex14_N PF04695.13 CDJ70366.1 - 0.001 19.8 68.6 0.009 16.7 5.4 5.0 5 0 0 5 5 4 3 Peroxisomal membrane anchor protein (Pex14p) conserved region Glypican PF01153.19 CDJ70366.1 - 0.0035 16.2 9.7 0.0035 16.2 9.7 3.1 3 0 0 3 3 3 1 Glypican DUF2721 PF11026.8 CDJ70366.1 - 0.0037 17.1 0.4 0.0037 17.1 0.4 4.0 5 0 0 5 5 4 1 Protein of unknown function (DUF2721) Otopetrin PF03189.13 CDJ70366.1 - 0.01 14.7 0.0 0.52 9.1 0.0 2.9 2 1 1 3 3 3 0 Otopetrin SPX PF03105.19 CDJ70366.1 - 0.2 11.5 29.3 0.55 10.1 1.1 3.3 3 0 0 3 3 3 0 SPX domain CDC45 PF02724.14 CDJ70366.1 - 1.1 7.4 28.8 0.014 13.7 12.8 3.2 3 1 0 3 3 3 0 CDC45-like protein Velvet PF11754.8 CDJ70366.1 - 1.8 8.4 43.9 2 8.3 1.1 3.7 3 1 0 3 3 3 0 Velvet factor Apt1 PF10351.9 CDJ70366.1 - 2 7.1 18.1 2.8 6.7 8.7 3.2 3 0 0 3 3 3 0 Golgi-body localisation protein domain RVP_2 PF08284.11 CDJ70368.1 - 1.1e-08 34.9 0.0 1.5e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ70368.1 - 3.7e-08 33.9 0.0 6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ70368.1 - 5.3e-07 30.1 0.0 8.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ70368.1 - 0.11 12.9 0.0 0.17 12.2 0.0 1.4 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ70368.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease YihI PF04220.12 CDJ70370.1 - 0.42 10.3 10.4 0.48 10.1 10.4 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) Suf PF05843.14 CDJ70370.1 - 1.4 8.8 10.8 1.5 8.7 10.8 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 CDJ70370.1 - 1.8 9.2 10.3 2 9.1 10.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 CDJ70370.1 - 2.2 7.1 14.6 2.2 7.1 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ70370.1 - 2.4 7.7 20.3 2.9 7.4 20.3 1.1 1 0 0 1 1 1 0 Spt20 family Coilin_N PF15862.5 CDJ70370.1 - 3.6 7.4 7.4 4.3 7.1 7.4 1.1 1 0 0 1 1 1 0 Coilin N-terminus Androgen_recep PF02166.16 CDJ70373.1 - 0.0018 17.2 7.3 0.0018 17.2 7.3 2.0 2 0 0 2 2 2 1 Androgen receptor Porin_4 PF13609.6 CDJ70373.1 - 0.029 14.1 1.5 0.032 14.0 1.5 1.2 1 0 0 1 1 1 0 Gram-negative porin UPF0560 PF10577.9 CDJ70373.1 - 0.21 10.1 3.6 0.24 9.9 3.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Rpp20 PF12328.8 CDJ70373.1 - 0.38 10.7 3.6 0.72 9.8 3.6 1.5 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF3824 PF12868.7 CDJ70373.1 - 0.46 11.1 11.9 0.59 10.8 3.2 2.1 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) TFIIA PF03153.13 CDJ70373.1 - 0.51 10.3 10.6 0.57 10.1 10.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ANAPC_CDC26 PF10471.9 CDJ70373.1 - 1.5 9.7 17.3 0.54 11.1 13.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 CYSTM PF12734.7 CDJ70373.1 - 2.9 8.3 9.6 6.6 7.1 9.6 1.7 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Ribosomal_60s PF00428.19 CDJ70373.1 - 9.3 6.9 20.0 2 9.1 12.7 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein Nmad5 PF18757.1 CDJ70374.1 - 0.0088 16.3 3.0 0.013 15.8 3.0 1.2 1 0 0 1 1 1 1 Nucleotide modification associated domain 5 Gemini_BL1 PF00845.19 CDJ70374.1 - 0.036 13.6 3.6 0.046 13.3 3.4 1.3 1 1 0 1 1 1 0 Geminivirus BL1 movement protein NtA PF03146.15 CDJ70374.1 - 0.17 11.8 0.3 0.35 10.7 0.1 1.6 2 0 0 2 2 2 0 Agrin NtA domain TFIIA PF03153.13 CDJ70374.1 - 0.28 11.1 27.4 0.45 10.5 27.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ70374.1 - 1.8 7.1 11.8 2.3 6.7 11.8 1.2 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 CDJ70374.1 - 3.2 6.3 11.9 3.9 6.0 11.9 1.0 1 0 0 1 1 1 0 Hamartin protein Cyto_heme_lyase PF01265.17 CDJ70374.1 - 3.6 7.1 9.0 4.3 6.8 9.0 1.3 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Presenilin PF01080.17 CDJ70374.1 - 6.2 5.5 9.6 8.3 5.0 9.6 1.3 1 0 0 1 1 1 0 Presenilin Ecl1 PF12855.7 CDJ70378.1 - 0.22 12.7 27.7 0.57 11.3 20.8 2.2 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins CAML PF14963.6 CDJ70378.1 - 2.2 8.4 13.9 3.9 7.5 1.7 2.1 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand SOG2 PF10428.9 CDJ70378.1 - 4.3 6.4 30.7 5.3 6.1 30.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PIH1 PF08190.12 CDJ70379.1 - 0.0011 18.4 0.3 0.0011 18.4 0.3 2.5 2 1 1 3 3 3 1 PIH1 N-terminal domain PIH1_CS PF18201.1 CDJ70379.1 - 0.0017 18.7 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain Spt20 PF12090.8 CDJ70380.1 - 2.8e-05 23.9 37.7 0.0021 17.7 14.3 3.3 3 0 0 3 3 3 3 Spt20 family DUF2722 PF10846.8 CDJ70380.1 - 0.0094 14.9 33.1 0.024 13.6 0.5 3.6 3 1 0 3 3 3 2 Protein of unknown function (DUF2722) DRY_EERY PF09750.9 CDJ70380.1 - 0.094 13.0 7.7 0.12 12.7 2.8 2.5 2 0 0 2 2 2 0 Alternative splicing regulator SpoIIP PF07454.11 CDJ70380.1 - 0.18 11.3 6.1 1.2 8.6 2.4 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF3408 PF11888.8 CDJ70380.1 - 0.28 11.3 10.5 0.23 11.6 2.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF3464 PF11947.8 CDJ70380.1 - 0.51 10.1 10.0 8.2 6.2 4.3 3.0 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 FixO PF02433.15 CDJ70380.1 - 0.91 8.9 5.0 0.39 10.1 0.7 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO MAS20 PF02064.15 CDJ70380.1 - 0.94 9.6 17.2 2.3 8.3 8.6 3.2 2 0 0 2 2 2 0 MAS20 protein import receptor G0-G1_switch_2 PF15103.6 CDJ70380.1 - 1.1 9.7 9.9 5.8 7.4 0.3 2.9 2 0 0 2 2 2 0 G0/G1 switch protein 2 GNAT_acetyltr_2 PF13718.6 CDJ70380.1 - 1.4 8.2 6.9 0.92 8.9 1.9 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase 2 dsDNA_bind PF01984.20 CDJ70380.1 - 1.5 9.2 39.3 2.7 8.3 18.0 3.6 3 0 0 3 3 3 0 Double-stranded DNA-binding domain eIF_4EBP PF05456.11 CDJ70380.1 - 2.4 8.1 11.7 4.1 7.4 3.3 2.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Zn_peptidase PF04228.13 CDJ70380.1 - 3.7 6.9 16.5 0.33 10.4 8.7 2.4 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Peptidase_S64 PF08192.11 CDJ70380.1 - 4.7 5.6 14.9 0.079 11.4 7.1 1.8 2 0 0 2 2 2 0 Peptidase family S64 2-Hacid_dh PF00389.30 CDJ70381.1 - 2.2e-28 98.6 0.3 3e-28 98.1 0.3 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 CDJ70381.1 - 2.3e-24 85.7 8.1 1.3e-15 57.2 0.0 3.0 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Spt20 PF12090.8 CDJ70381.1 - 3 7.4 19.2 4.3 6.9 19.2 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ70382.1 - 0.00039 19.5 24.0 0.0013 17.8 14.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) DUF3801 PF12687.7 CDJ70382.1 - 0.0036 17.4 9.1 0.0058 16.7 9.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3801) DUF3408 PF11888.8 CDJ70382.1 - 0.53 10.4 8.2 0.21 11.7 4.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) SR-25 PF10500.9 CDJ70382.1 - 0.61 9.7 27.0 0.3 10.6 24.1 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SLC12 PF03522.15 CDJ70382.1 - 0.64 9.0 8.1 0.79 8.7 8.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Miga PF10265.9 CDJ70382.1 - 1.9 7.3 10.1 2.7 6.9 10.1 1.3 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 CDJ70382.1 - 2.2 7.0 14.0 3.3 6.5 14.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 CDJ70382.1 - 2.2 5.3 19.2 2.8 5.0 19.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 CDJ70382.1 - 3.4 6.3 19.2 4.3 5.9 19.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 CDJ70382.1 - 3.6 5.7 19.4 4.6 5.4 19.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3464 PF11947.8 CDJ70382.1 - 6.2 6.6 15.9 28 4.4 15.9 2.1 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 Hid1 PF12722.7 CDJ70382.1 - 8.1 4.4 17.5 12 3.9 17.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glutaredoxin PF00462.24 CDJ70383.1 - 1.7e-06 28.1 0.1 0.0053 17.0 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin TFIIA PF03153.13 CDJ70383.1 - 3.5e-05 24.0 69.8 0.015 15.3 37.1 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ70383.1 - 0.0026 16.6 31.2 0.0048 15.7 12.1 2.2 2 0 0 2 2 2 2 Presenilin CLN3 PF02487.17 CDJ70383.1 - 0.04 13.0 20.4 0.014 14.5 5.9 2.2 2 0 0 2 2 2 0 CLN3 protein SpoIIP PF07454.11 CDJ70383.1 - 0.046 13.2 28.1 0.34 10.3 11.5 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Apt1 PF10351.9 CDJ70383.1 - 0.07 12.0 22.7 0.27 10.0 11.7 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain HemX PF04375.14 CDJ70383.1 - 0.075 12.3 54.2 0.056 12.7 27.5 2.5 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase NPR3 PF03666.13 CDJ70383.1 - 0.11 11.2 24.3 0.079 11.7 9.5 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SID-1_RNA_chan PF13965.6 CDJ70383.1 - 0.12 10.8 9.6 0.6 8.5 0.5 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 CobT PF06213.12 CDJ70383.1 - 0.16 11.3 53.4 0.058 12.8 18.2 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT OATP PF03137.20 CDJ70383.1 - 0.2 9.9 14.8 0.055 11.8 3.2 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Lin-8 PF03353.15 CDJ70383.1 - 0.2 11.2 32.9 0.029 14.0 15.3 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.13 CDJ70383.1 - 0.21 11.4 25.8 0.45 10.3 8.0 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CDC45 PF02724.14 CDJ70383.1 - 0.25 9.6 25.6 0.061 11.6 9.8 2.1 2 0 0 2 2 2 0 CDC45-like protein SRP-alpha_N PF04086.13 CDJ70383.1 - 0.26 11.2 26.6 0.32 10.9 9.1 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Tim54 PF11711.8 CDJ70383.1 - 0.3 9.8 22.6 0.46 9.2 9.1 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 LMBR1 PF04791.16 CDJ70383.1 - 0.51 9.2 16.1 0.69 8.8 16.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PNISR PF15996.5 CDJ70383.1 - 0.56 10.5 41.4 0.067 13.5 8.3 2.4 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR FAM60A PF15396.6 CDJ70383.1 - 0.91 9.5 24.5 2.4 8.1 10.6 2.4 2 0 0 2 2 2 0 Protein Family FAM60A DUF5523 PF17661.1 CDJ70383.1 - 1.1 8.9 31.0 1.9 8.1 7.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) CNDH2_C PF16858.5 CDJ70383.1 - 1.6 8.6 28.4 1.5 8.6 5.6 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Striatin PF08232.12 CDJ70383.1 - 1.8 9.2 38.3 0.53 10.9 19.3 2.5 2 0 0 2 2 2 0 Striatin family Sin_N PF04801.13 CDJ70383.1 - 1.9 7.6 42.1 2.2 7.4 24.9 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region Tyrosinase PF00264.20 CDJ70383.1 - 2.2 8.5 11.3 3.4 7.9 4.2 2.2 2 0 0 2 2 2 0 Common central domain of tyrosinase Gti1_Pac2 PF09729.9 CDJ70383.1 - 2.2 8.3 28.0 5.4 7.1 6.8 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family SPX PF03105.19 CDJ70383.1 - 3 7.7 30.6 4.6 7.0 17.2 2.1 2 0 0 2 2 2 0 SPX domain DUF2052 PF09747.9 CDJ70383.1 - 3.1 7.9 36.8 3.4 7.8 9.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SOBP PF15279.6 CDJ70383.1 - 3.9 8.0 26.6 7.6 7.0 6.5 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein Adaptin_binding PF10199.9 CDJ70383.1 - 4.4 7.9 28.3 8.3 7.0 6.4 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Med15 PF09606.10 CDJ70383.1 - 5.1 5.7 75.4 1.1 7.8 44.5 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.12 CDJ70383.1 - 5.7 6.7 38.0 5.7 6.7 19.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 CDJ70383.1 - 5.8 4.9 27.7 0.97 7.5 11.1 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein AUX_IAA PF02309.16 CDJ70383.1 - 5.8 6.7 19.7 5.2 6.9 8.2 2.4 2 0 0 2 2 2 0 AUX/IAA family eIF-3_zeta PF05091.12 CDJ70383.1 - 7 5.5 40.7 0.78 8.6 7.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sec62 PF03839.16 CDJ70383.1 - 7.2 6.1 23.8 1.7 8.1 9.9 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 Exonuc_VII_L PF02601.15 CDJ70383.1 - 7.4 6.1 38.6 0.34 10.4 15.2 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit PA26 PF04636.13 CDJ70383.1 - 7.6 5.3 23.3 3 6.7 9.5 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) MCM_bind PF09739.9 CDJ70383.1 - 8.2 4.7 27.7 2.4 6.5 12.6 2.1 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor DUF1645 PF07816.11 CDJ70384.1 - 0.011 16.3 12.5 0.37 11.3 5.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) SPX PF03105.19 CDJ70384.1 - 0.11 12.3 3.0 0.14 12.1 3.0 1.2 1 0 0 1 1 1 0 SPX domain Secretin_N_2 PF07655.13 CDJ70384.1 - 1.7 9.3 16.7 3.1 8.4 7.2 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain FAM104 PF15434.6 CDJ70384.1 - 4.8 7.8 14.4 4.9 7.8 5.1 2.4 2 0 0 2 2 2 0 Family 104 DNA_ligase_A_N PF04675.14 CDJ70385.1 - 2.8e-26 92.9 1.4 5.4e-26 92.0 0.0 2.3 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 CDJ70385.1 - 5.6e-07 29.4 0.0 5.6e-07 29.4 0.0 2.4 2 1 0 2 2 2 1 ATP dependent DNA ligase domain AAA_23 PF13476.6 CDJ70385.1 - 2.4 8.6 20.7 6.5 7.2 20.7 1.7 1 0 0 1 1 1 0 AAA domain Rap1_C PF11626.8 CDJ70387.1 - 0.33 11.1 4.4 0.28 11.3 0.9 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TIP_N PF12457.8 CDJ70387.1 - 0.34 11.3 9.1 0.42 11.0 2.6 2.4 2 1 0 2 2 2 0 Tuftelin interacting protein N terminal DUF4834 PF16118.5 CDJ70387.1 - 0.39 11.7 20.2 2.2 9.3 1.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4083 PF13314.6 CDJ70387.1 - 1.9 8.5 4.4 0.36 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) EamA PF00892.20 CDJ70388.1 - 2.1e-10 40.9 17.3 2.1e-10 40.9 17.3 2.4 2 0 0 2 2 2 1 EamA-like transporter family DAP10 PF07213.11 CDJ70388.1 - 1.2 9.2 5.3 0.76 9.8 1.6 2.7 2 0 0 2 2 2 0 DAP10 membrane protein ABC2_membrane_5 PF13346.6 CDJ70388.1 - 3.1 7.3 13.2 0.32 10.5 6.0 2.4 1 1 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 CDJ70390.1 - 2e-34 118.9 22.6 2.6e-34 118.5 22.6 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CDJ70390.1 - 2.9e-23 82.9 0.0 8.5e-23 81.4 0.0 1.8 1 1 1 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 CDJ70390.1 - 7.1e-06 25.4 18.0 9.2e-06 25.0 16.5 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CDJ70390.1 - 0.00012 22.0 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 CDJ70390.1 - 0.0036 16.9 0.0 0.0091 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ70390.1 - 0.0038 16.9 0.1 0.01 15.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ70390.1 - 0.0082 16.2 0.2 0.017 15.2 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC2_membrane_2 PF12679.7 CDJ70390.1 - 0.039 13.2 11.2 0.063 12.6 11.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 CDJ70390.1 - 0.045 14.2 0.0 0.085 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ70390.1 - 0.079 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 CDJ70390.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Dynamin family AAA_21 PF13304.6 CDJ70390.1 - 0.14 11.9 0.1 7.6 6.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SURF1 PF02104.15 CDJ70392.1 - 1e-26 94.3 0.3 1.9e-17 64.0 0.0 2.8 2 1 0 2 2 2 2 SURF1 family DUF4392 PF14336.6 CDJ70392.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DUF2500 PF10694.9 CDJ70392.1 - 0.58 10.7 1.9 0.6 10.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) EFTUD2 PF16004.5 CDJ70392.1 - 0.61 10.7 7.2 7.6 7.1 0.0 3.0 3 0 0 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus WW PF00397.26 CDJ70393.1 - 5e-07 29.7 1.3 1.2e-06 28.5 1.3 1.7 1 0 0 1 1 1 1 WW domain DegT_DnrJ_EryC1 PF01041.17 CDJ70395.1 - 3.4e-16 59.5 0.0 5.5e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Dynein_C PF18199.1 CDJ70396.1 - 8.2e-70 235.4 0.0 1.1e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 CDJ70396.1 - 2.1e-37 127.8 0.0 4.3e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 CDJ70396.1 - 2.6e-35 121.7 0.0 7.2e-35 120.2 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_9 PF12781.7 CDJ70397.1 - 2.5e-24 85.7 1.2 3.5e-24 85.1 1.2 1.2 1 0 0 1 1 1 1 ATP-binding dynein motor region LcrV PF04792.12 CDJ70397.1 - 0.0042 16.4 0.1 0.0066 15.8 0.1 1.2 1 0 0 1 1 1 1 V antigen (LcrV) protein Cofac_haem_bdg PF04187.13 CDJ70397.1 - 0.014 15.4 0.1 0.037 14.0 0.0 1.6 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN SesA PF17107.5 CDJ70397.1 - 0.066 13.4 0.3 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MT PF12777.7 CDJ70398.1 - 2.5e-43 148.4 5.4 3.4e-43 148.0 5.4 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 CDJ70398.1 - 1.1e-23 83.9 0.0 2e-19 70.0 0.0 2.5 1 1 1 2 2 2 2 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ70398.1 - 2.4e-20 72.6 3.5 5.1e-20 71.5 0.0 2.7 3 0 0 3 3 3 1 ATP-binding dynein motor region Spc7 PF08317.11 CDJ70398.1 - 0.00043 19.3 5.5 0.00043 19.3 5.5 2.4 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF745 PF05335.13 CDJ70398.1 - 0.0019 18.0 16.9 0.0025 17.6 2.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF745) Laminin_I PF06008.14 CDJ70398.1 - 0.0047 16.7 1.7 0.0047 16.7 1.7 2.3 2 0 0 2 2 2 1 Laminin Domain I DHR10 PF18595.1 CDJ70398.1 - 0.0097 16.0 6.3 0.0097 16.0 6.3 2.9 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain TelA PF05816.11 CDJ70398.1 - 0.12 11.4 9.3 1.6 7.7 2.8 2.6 2 1 0 2 2 2 0 Toxic anion resistance protein (TelA) Sec8_exocyst PF04048.14 CDJ70398.1 - 0.12 12.3 8.3 0.54 10.1 1.9 3.8 2 2 2 4 4 4 0 Sec8 exocyst complex component specific domain Sec34 PF04136.15 CDJ70398.1 - 0.15 11.9 4.4 0.4 10.6 0.3 2.8 2 1 0 2 2 2 0 Sec34-like family Laminin_II PF06009.12 CDJ70398.1 - 0.18 11.8 9.6 0.48 10.4 0.9 2.9 2 1 0 2 2 2 0 Laminin Domain II ERM PF00769.19 CDJ70398.1 - 0.19 11.5 20.6 1.2 8.9 7.8 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Exonuc_VII_L PF02601.15 CDJ70398.1 - 0.24 10.9 16.1 0.11 12.0 2.9 2.2 1 1 0 2 2 2 0 Exonuclease VII, large subunit DASH_Spc34 PF08657.10 CDJ70398.1 - 0.26 11.1 5.5 1.2 8.9 0.3 2.3 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF1664 PF07889.12 CDJ70398.1 - 0.32 11.0 10.2 1 9.4 0.6 3.0 3 1 0 3 3 2 0 Protein of unknown function (DUF1664) AcylCoA_dehyd_C PF12186.8 CDJ70398.1 - 0.35 11.0 4.7 1.6 8.9 0.2 3.4 4 1 0 4 4 3 0 Acyl-CoA dehydrogenase C terminal Plk4_PB2 PF18409.1 CDJ70398.1 - 0.35 11.6 4.5 0.22 12.2 0.4 2.6 2 1 1 3 3 2 0 Polo-like Kinase 4 Polo Box 2 Fez1 PF06818.15 CDJ70398.1 - 0.36 11.3 11.8 0.18 12.3 2.1 2.4 2 0 0 2 2 2 0 Fez1 V_ATPase_I PF01496.19 CDJ70398.1 - 0.65 7.8 6.5 1.6 6.5 0.4 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.10 CDJ70398.1 - 0.75 10.2 17.1 0.096 13.1 5.5 3.1 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Fib_alpha PF08702.10 CDJ70398.1 - 0.89 9.7 5.0 0.99 9.6 0.6 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 CDJ70398.1 - 0.95 9.9 12.4 0.03 14.7 3.7 2.7 2 0 0 2 2 2 0 Cell division protein ZapB Phage_GP20 PF06810.11 CDJ70398.1 - 0.98 9.2 13.7 4.2 7.2 2.6 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 UPF0242 PF06785.11 CDJ70398.1 - 1.2 9.2 10.7 0.2 11.8 3.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 CDJ70398.1 - 1.5 9.1 14.6 0.047 13.9 2.2 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PMEI PF04043.15 CDJ70398.1 - 1.5 9.2 8.7 5.3 7.4 0.3 2.9 2 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor CorA PF01544.18 CDJ70398.1 - 2.4 7.4 5.0 0.68 9.2 0.3 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DivIVA PF05103.13 CDJ70398.1 - 2.8 8.0 16.8 1.5 8.9 4.0 3.2 2 1 1 3 3 3 0 DivIVA protein BLOC1_2 PF10046.9 CDJ70398.1 - 2.9 8.3 8.7 6 7.3 3.5 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CRR7 PF12095.8 CDJ70398.1 - 3 8.3 5.7 6.8 7.2 0.4 4.0 3 2 2 6 6 4 0 Protein CHLORORESPIRATORY REDUCTION 7 CLZ PF16526.5 CDJ70398.1 - 3.4 8.1 8.1 0.62 10.5 1.7 3.1 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PCRF PF03462.18 CDJ70398.1 - 3.9 7.3 14.5 1 9.2 3.3 3.2 2 1 1 3 3 3 0 PCRF domain Phage_GPO PF05929.11 CDJ70398.1 - 4.5 6.8 8.7 5 6.7 0.7 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase ADIP PF11559.8 CDJ70398.1 - 9.4 6.3 15.1 3.5 7.7 2.6 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_7 PF12775.7 CDJ70399.1 - 1.1e-38 132.5 0.0 1.7e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_1 PF17857.1 CDJ70399.1 - 5.2e-13 49.1 0.1 1.3e-12 47.8 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDJ70399.1 - 0.00016 22.1 0.1 0.0003 21.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ70399.1 - 0.00094 19.2 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDJ70399.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain TIP49 PF06068.13 CDJ70399.1 - 0.0059 15.9 0.0 0.02 14.1 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain Imm48 PF15574.6 CDJ70399.1 - 0.015 15.1 0.0 5 6.9 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 48 AAA PF00004.29 CDJ70399.1 - 0.018 15.5 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thy1 PF02511.15 CDJ70399.1 - 0.083 12.7 0.0 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Thymidylate synthase complementing protein AAA_30 PF13604.6 CDJ70399.1 - 0.093 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CDJ70399.1 - 0.1 12.0 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_lid_8 PF17868.1 CDJ70399.1 - 0.11 12.3 0.3 0.36 10.8 0.2 1.8 2 0 0 2 2 2 0 AAA lid domain NACHT PF05729.12 CDJ70399.1 - 0.12 12.3 0.2 0.42 10.5 0.2 2.0 1 1 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 CDJ70399.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_6 PF12774.7 CDJ70400.1 - 2.3e-50 171.4 0.1 9.1e-50 169.5 0.0 1.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CDJ70400.1 - 2.1e-09 37.5 0.1 3.9e-07 30.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDJ70400.1 - 0.00077 20.0 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ70400.1 - 0.0016 18.8 0.0 0.0039 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CDJ70400.1 - 0.0038 16.9 0.1 0.044 13.5 0.0 2.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CDJ70400.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CDJ70400.1 - 0.019 15.1 0.1 0.041 14.0 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 CDJ70400.1 - 0.021 15.2 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase L27 PF02828.16 CDJ70400.1 - 0.025 14.3 0.2 0.064 13.0 0.2 1.6 1 0 0 1 1 1 0 L27 domain RsgA_GTPase PF03193.16 CDJ70400.1 - 0.056 13.3 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Viral_helicase1 PF01443.18 CDJ70400.1 - 0.08 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CDJ70400.1 - 0.09 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CDJ70400.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 CDJ70400.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CDJ70400.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DHC_N2 PF08393.13 CDJ70401.1 - 3.1e-54 184.6 5.2 4.3e-54 184.2 2.3 2.3 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 CDJ70401.1 - 2.9e-17 62.6 0.2 4.8e-17 61.9 0.2 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Flagellin_C PF00700.21 CDJ70401.1 - 0.011 16.1 0.5 0.21 12.0 0.1 2.5 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region DHC_N2 PF08393.13 CDJ70402.1 - 6.5e-15 55.1 0.3 6.5e-15 55.1 0.3 2.9 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 DegS PF05384.11 CDJ70402.1 - 0.0019 17.7 3.6 0.026 14.0 2.4 2.8 2 0 0 2 2 2 1 Sensor protein DegS FAD-SLDH PF12318.8 CDJ70402.1 - 0.69 10.0 3.3 1.8 8.6 0.2 2.8 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Exonuc_VII_L PF02601.15 CDJ70403.1 - 0.14 11.7 5.2 0.18 11.3 5.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_A17 PF05380.13 CDJ70403.1 - 0.56 10.2 6.9 1.2 9.2 1.9 2.5 1 1 1 2 2 2 0 Pao retrotransposon peptidase MeaB PF03308.16 CDJ70403.1 - 0.77 8.7 5.0 1.1 8.2 5.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2362 PF10154.9 CDJ70403.1 - 1.9 7.3 12.7 2.7 6.9 12.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Retrotrans_gag PF03732.17 CDJ70403.1 - 3.8 7.9 12.8 2.1 8.7 9.1 2.3 2 1 1 3 3 3 0 Retrotransposon gag protein DUF883 PF05957.13 CDJ70403.1 - 9.3 6.9 9.4 21 5.8 0.7 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) UCH PF00443.29 CDJ70404.1 - 1.5e-44 152.5 0.0 4.6e-44 150.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDJ70404.1 - 1.4e-11 44.5 0.0 7.3e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CDJ70404.1 - 4.5e-11 42.9 0.4 4.9e-05 23.1 1.3 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CDJ70404.1 - 2.2e-10 40.2 1.2 0.00011 22.1 0.1 3.1 3 0 0 3 3 3 2 UBA/TS-N domain RuvA_C PF07499.13 CDJ70404.1 - 0.017 15.5 4.0 0.59 10.6 0.1 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain Dis3l2_C_term PF17877.1 CDJ70404.1 - 0.03 14.6 0.3 0.12 12.7 0.3 2.0 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal zf-UBP_var PF17807.1 CDJ70404.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger SRP14 PF02290.15 CDJ70405.1 - 1.4e-17 63.8 3.4 2.7e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Spt20 PF12090.8 CDJ70405.1 - 0.46 10.1 16.4 0.52 9.9 16.4 1.1 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ70405.1 - 0.57 11.2 8.3 0.96 10.4 8.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ70405.1 - 0.92 8.2 8.0 0.96 8.1 8.0 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ70405.1 - 1.5 8.8 4.1 1.4 8.9 4.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region rve PF00665.26 CDJ70406.1 - 5.4e-12 45.9 0.0 8.6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ70406.1 - 1.8e-05 24.6 0.0 3.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Nop14 PF04147.12 CDJ70407.1 - 0.00036 18.9 33.1 0.00036 18.9 33.1 1.0 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 CDJ70407.1 - 0.03 12.8 31.0 0.041 12.3 31.0 1.3 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 CDJ70407.1 - 0.037 12.3 34.4 0.044 12.1 34.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 CDJ70407.1 - 0.05 13.2 18.8 0.053 13.1 18.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop53 PF07767.11 CDJ70407.1 - 0.056 12.8 39.5 0.082 12.3 39.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GAGA_bind PF06217.12 CDJ70407.1 - 0.27 11.5 12.9 0.33 11.2 12.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 CDJ70407.1 - 0.31 10.9 28.1 0.43 10.4 28.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 CDJ70407.1 - 0.35 10.3 43.5 0.43 10.0 43.5 1.1 1 0 0 1 1 1 0 SDA1 Rrn6 PF10214.9 CDJ70407.1 - 0.67 8.4 13.7 0.71 8.3 13.7 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4614 PF15391.6 CDJ70407.1 - 0.72 9.8 14.4 1.1 9.2 14.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF4045 PF13254.6 CDJ70407.1 - 0.87 9.2 20.8 0.98 9.0 20.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GREB1 PF15782.5 CDJ70407.1 - 1 6.4 19.4 1.3 6.1 19.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Cwf_Cwc_15 PF04889.12 CDJ70407.1 - 1.1 8.9 38.4 1.6 8.4 38.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Suf PF05843.14 CDJ70407.1 - 1.1 9.1 12.3 1.3 9.0 12.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Apt1 PF10351.9 CDJ70407.1 - 1.4 7.7 17.2 1.6 7.5 17.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TipE PF16972.5 CDJ70407.1 - 1.6 7.8 6.3 2 7.5 6.3 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE CCSAP PF15748.5 CDJ70407.1 - 1.6 8.8 24.4 1.9 8.6 24.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Neur_chan_memb PF02932.16 CDJ70407.1 - 2.1 8.3 10.3 2.5 8.1 10.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PNISR PF15996.5 CDJ70407.1 - 2.3 8.4 32.2 3.6 7.8 32.2 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Peptidase_S64 PF08192.11 CDJ70407.1 - 4.7 5.6 13.1 5 5.5 13.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Glypican PF01153.19 CDJ70407.1 - 4.9 5.9 15.6 6 5.6 15.6 1.1 1 0 0 1 1 1 0 Glypican LAP1C PF05609.12 CDJ70407.1 - 5.1 6.1 21.0 6 5.8 21.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DNA_pol_phi PF04931.13 CDJ70407.1 - 5.3 5.0 38.6 7.3 4.6 38.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ndc1_Nup PF09531.10 CDJ70407.1 - 5.8 5.5 11.8 7.3 5.1 11.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 CDJ70407.1 - 7 5.2 13.2 7.9 5.0 13.2 1.0 1 0 0 1 1 1 0 Hamartin protein DUF2151 PF10221.9 CDJ70407.1 - 9 4.8 16.1 10 4.6 16.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator SpoIIP PF07454.11 CDJ70409.1 - 0.00032 20.2 29.0 0.014 14.8 13.8 2.0 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 CDJ70409.1 - 0.0037 17.4 31.5 0.12 12.5 8.9 2.2 2 0 0 2 2 2 2 E2F-associated phosphoprotein RPA43_OB PF17875.1 CDJ70409.1 - 0.0048 17.5 22.7 0.26 11.9 9.3 2.1 2 0 0 2 2 2 2 RPA43 OB domain in RNA Pol I SAPS PF04499.15 CDJ70409.1 - 0.023 13.5 17.8 0.031 13.1 17.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein EIIBC-GUT_N PF03612.14 CDJ70409.1 - 0.023 14.5 28.6 0.06 13.1 5.2 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Afi1 PF07792.12 CDJ70409.1 - 0.03 14.8 24.9 0.38 11.2 11.8 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TFIIA PF03153.13 CDJ70409.1 - 0.034 14.1 83.2 0.027 14.5 42.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FYDLN_acid PF09538.10 CDJ70409.1 - 0.062 14.0 17.9 0.12 13.1 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SAGA-Tad1 PF12767.7 CDJ70409.1 - 0.079 12.7 22.7 0.11 12.2 22.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit EBP50_C PF09007.11 CDJ70409.1 - 0.1 13.6 21.2 0.12 13.4 7.5 2.1 2 0 0 2 2 2 0 EBP50, C-terminal DUF2076 PF09849.9 CDJ70409.1 - 0.11 12.5 64.7 0.16 12.0 17.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) GramPos_pilinD1 PF16555.5 CDJ70409.1 - 0.13 12.4 18.5 0.097 12.8 5.8 2.1 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain Band_3_cyto PF07565.13 CDJ70409.1 - 0.16 11.7 30.3 0.16 11.7 13.3 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4820 PF16091.5 CDJ70409.1 - 0.22 10.8 24.9 0.024 14.0 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Rxt3 PF08642.10 CDJ70409.1 - 0.32 11.8 20.3 0.28 12.0 1.8 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 LIM_bind PF01803.16 CDJ70409.1 - 0.35 10.4 34.8 0.052 13.1 15.9 2.1 2 0 0 2 2 2 0 LIM-domain binding protein Connexin PF00029.19 CDJ70409.1 - 0.4 10.4 27.3 0.61 9.8 4.1 2.1 2 0 0 2 2 2 0 Connexin MPM1 PF17234.2 CDJ70409.1 - 0.43 10.8 35.7 0.14 12.4 14.1 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 BORG_CEP PF14957.6 CDJ70409.1 - 0.43 11.8 20.8 0.81 10.9 8.6 2.1 2 0 0 2 2 2 0 Cdc42 effector RNA_pol_Rpc4 PF05132.14 CDJ70409.1 - 0.44 11.0 29.6 0.93 9.9 14.9 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 Folate_carrier PF01770.18 CDJ70409.1 - 0.57 8.9 21.5 1.3 7.7 5.4 2.0 2 0 0 2 2 2 0 Reduced folate carrier DUF3807 PF12720.7 CDJ70409.1 - 0.64 10.3 46.4 1.9 8.8 11.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) ATAD4 PF15321.6 CDJ70409.1 - 0.7 11.3 23.3 0.99 10.8 8.3 2.4 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DUF2072 PF09845.9 CDJ70409.1 - 0.75 10.1 22.2 2.6 8.3 10.1 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein DUF5427 PF10310.9 CDJ70409.1 - 0.91 8.4 38.3 0.12 11.4 18.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Pex14_N PF04695.13 CDJ70409.1 - 0.95 10.1 58.8 0.41 11.3 16.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NPR3 PF03666.13 CDJ70409.1 - 0.95 8.2 28.9 0.46 9.2 14.1 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 BRF1 PF07741.13 CDJ70409.1 - 1 9.8 32.3 1.3 9.4 15.3 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF4045 PF13254.6 CDJ70409.1 - 1.1 8.9 26.2 0.19 11.4 10.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Peptidase_S49_N PF08496.10 CDJ70409.1 - 1.1 9.3 33.0 0.48 10.5 13.6 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.12 CDJ70409.1 - 1.2 8.1 49.9 0.17 10.8 11.7 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GCD14 PF08704.10 CDJ70409.1 - 1.5 8.5 14.2 2.3 7.8 2.2 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit RP-C_C PF11800.8 CDJ70409.1 - 1.6 8.8 25.7 1.8 8.6 12.1 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region PPL5 PF18168.1 CDJ70409.1 - 1.7 7.8 26.2 0.07 12.4 1.1 2.0 2 0 0 2 2 2 0 Prim-pol family 5 Peptidase_S64 PF08192.11 CDJ70409.1 - 1.8 6.9 30.1 2.3 6.6 30.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 V_ATPase_I PF01496.19 CDJ70409.1 - 1.9 6.3 37.1 0.058 11.3 5.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family XAP5 PF04921.14 CDJ70409.1 - 1.9 8.3 21.0 0.46 10.3 6.4 2.2 2 0 0 2 2 2 0 XAP5, circadian clock regulator MCU PF04678.13 CDJ70409.1 - 1.9 8.5 24.5 1.1 9.4 3.5 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter AIF_C PF14721.6 CDJ70409.1 - 2 8.8 30.4 1.3 9.4 6.4 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MecA PF05389.12 CDJ70409.1 - 2.1 7.9 29.6 0.11 12.2 4.1 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) CPSF100_C PF13299.6 CDJ70409.1 - 2.2 8.4 30.4 0.28 11.4 3.8 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Ribosomal_L37 PF08561.10 CDJ70409.1 - 2.4 8.7 21.8 3.2 8.3 9.2 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 ATP11 PF06644.11 CDJ70409.1 - 2.4 7.9 34.9 1.6 8.5 16.4 2.1 2 0 0 2 2 2 0 ATP11 protein DUF1645 PF07816.11 CDJ70409.1 - 2.6 8.6 17.0 1.3 9.5 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) RPN2_C PF18004.1 CDJ70409.1 - 2.6 7.9 29.7 1.2 9.1 12.5 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 CDJ70409.1 - 2.9 7.2 25.8 0.39 10.1 9.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF719 PF05334.13 CDJ70409.1 - 3 8.0 28.5 2.4 8.3 11.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Sec62 PF03839.16 CDJ70409.1 - 3 7.3 29.0 3.5 7.1 12.1 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 CSG2 PF16965.5 CDJ70409.1 - 3.3 6.6 23.5 0.073 12.0 1.2 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator OATP PF03137.20 CDJ70409.1 - 3.3 5.9 20.4 2.3 6.4 4.4 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PIP5K PF01504.18 CDJ70409.1 - 3.8 6.7 31.0 0.3 10.3 4.3 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase MMU163 PF17119.5 CDJ70409.1 - 4.2 6.5 19.6 1.3 8.1 2.4 2.1 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis FCP1_C PF09309.10 CDJ70409.1 - 4.3 7.1 26.7 1.8 8.4 5.2 2.3 2 0 0 2 2 2 0 FCP1, C-terminal DUF3408 PF11888.8 CDJ70409.1 - 5 7.3 37.4 0.97 9.6 8.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Ctr PF04145.15 CDJ70409.1 - 5.2 7.7 24.2 1.3 9.7 2.4 2.1 2 0 0 2 2 2 0 Ctr copper transporter family DUF913 PF06025.12 CDJ70409.1 - 5.4 5.9 22.6 0.86 8.5 1.7 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FAM176 PF14851.6 CDJ70409.1 - 5.7 6.6 23.9 4.1 7.1 4.5 2.2 2 0 0 2 2 2 0 FAM176 family PSK PF06404.12 CDJ70409.1 - 6 7.9 33.0 7.4 7.7 9.6 2.3 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) MMR1 PF08505.10 CDJ70409.1 - 6.1 7.1 42.0 0.35 11.1 17.2 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Isy1 PF06246.12 CDJ70409.1 - 7.4 6.0 33.2 4.4 6.8 16.0 2.1 2 0 0 2 2 2 0 Isy1-like splicing family Asparaginase_2 PF01112.18 CDJ70409.1 - 8.2 5.4 24.2 2.6 7.0 9.8 2.1 2 0 0 2 2 2 0 Asparaginase DUF2370 PF10176.9 CDJ70409.1 - 8.6 5.9 18.9 5.7 6.5 7.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) FmiP_Thoc5 PF09766.9 CDJ70409.1 - 8.7 5.5 45.7 0.047 13.0 9.0 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Serinc PF03348.15 CDJ70409.1 - 9.4 5.0 23.1 0.8 8.6 2.0 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) ANAPC10 PF03256.16 CDJ70411.1 - 4.9e-25 88.2 0.0 2.2e-24 86.1 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 CDJ70411.1 - 0.032 14.4 0.2 0.073 13.2 0.0 1.7 2 0 0 2 2 2 0 F5/8 type C domain DUF4148 PF13663.6 CDJ70411.1 - 0.066 13.4 6.2 5 7.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) SR-25 PF10500.9 CDJ70411.1 - 1.3 8.5 7.0 2 8.0 7.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIF_beta PF02270.15 CDJ70412.1 - 0.00039 20.5 0.1 0.0007 19.7 0.1 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 CDJ70412.1 - 0.022 15.4 0.0 0.042 14.5 0.0 1.5 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus Ribosomal_L22 PF00237.19 CDJ70413.1 - 0.00055 20.1 0.1 0.0016 18.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e SR-25 PF10500.9 CDJ70413.1 - 0.0079 15.8 12.5 0.014 15.0 12.5 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Herpes_UL20 PF04544.12 CDJ70413.1 - 0.045 14.1 0.2 0.073 13.4 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 SPX PF03105.19 CDJ70413.1 - 0.071 13.0 1.0 0.09 12.7 1.0 1.2 1 0 0 1 1 1 0 SPX domain RAP1 PF07218.11 CDJ70413.1 - 5.2 5.2 10.9 7.1 4.8 10.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ70415.1 - 0.031 13.9 6.1 0.047 13.3 6.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ70415.1 - 5.1 7.8 7.2 8.8 7.1 7.2 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF4131 PF13567.6 CDJ70415.1 - 8.6 6.0 13.3 1.6 8.3 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3292 PF11696.8 CDJ70416.1 - 0.55 8.5 10.1 0.68 8.2 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) SPX PF03105.19 CDJ70416.1 - 0.88 9.4 9.1 1.1 9.2 9.1 1.1 1 0 0 1 1 1 0 SPX domain IHABP4_N PF16174.5 CDJ70416.1 - 2 9.0 19.7 3.4 8.3 19.7 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal ELFV_dehydrog PF00208.21 CDJ70418.1 - 3e-28 99.2 0.0 8.1e-27 94.5 0.0 2.1 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Med3 PF11593.8 CDJ70418.1 - 0.0051 16.1 1.1 0.0064 15.7 1.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal SUIM_assoc PF16619.5 CDJ70418.1 - 0.0088 16.1 6.7 0.0088 16.1 6.7 2.0 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ70418.1 - 0.016 14.2 0.9 0.017 14.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ70418.1 - 0.074 12.6 7.8 0.11 12.2 7.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ70418.1 - 0.098 13.6 4.8 0.21 12.6 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 CDJ70418.1 - 3.5 6.4 8.8 4.7 5.9 8.8 1.1 1 0 0 1 1 1 0 Androgen receptor Jun PF03957.13 CDJ70419.1 - 9.5e-06 25.7 2.6 1.2e-05 25.3 2.6 1.1 1 0 0 1 1 1 1 Jun-like transcription factor ELFV_dehydrog PF00208.21 CDJ70419.1 - 0.00062 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Period_C PF12114.8 CDJ70420.1 - 0.18 11.3 11.2 0.21 11.1 0.8 2.5 2 0 0 2 2 2 0 Period protein 2/3C-terminal region JUPITER PF17054.5 CDJ70420.1 - 3.9 6.9 8.3 5.4 6.4 8.3 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Activator_LAG-3 PF11498.8 CDJ70420.1 - 9.2 5.1 24.0 16 4.3 24.0 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RLI PF04068.15 CDJ70421.1 - 2.4e-14 52.8 5.0 3.8e-14 52.2 5.0 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AF-4 PF05110.13 CDJ70421.1 - 0.0087 14.2 5.7 0.0074 14.5 5.7 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ70421.1 - 0.016 14.8 15.2 0.021 14.4 15.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 CDJ70421.1 - 0.72 7.9 4.5 0.76 7.8 4.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF755 PF05501.11 CDJ70421.1 - 0.82 10.0 17.6 1.7 9.0 17.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RAP1 PF07218.11 CDJ70421.1 - 3.3 5.9 8.3 3.7 5.7 8.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Hydrolase_6 PF13344.6 CDJ70422.1 - 4e-27 94.3 0.0 1e-26 93.0 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SUIM_assoc PF16619.5 CDJ70422.1 - 0.00099 19.1 3.9 0.00099 19.1 3.9 2.8 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ70422.1 - 0.016 15.2 8.6 0.019 15.0 8.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydrolase PF00702.26 CDJ70422.1 - 0.041 14.2 0.0 0.075 13.3 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_L18p PF00861.22 CDJ70422.1 - 0.11 12.9 0.5 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast XPG_I PF00867.18 CDJ70422.1 - 0.26 11.7 3.3 0.19 12.1 0.4 2.2 2 1 0 2 2 2 0 XPG I-region Ipi1_N PF12333.8 CDJ70422.1 - 0.56 10.8 5.5 9 7.0 0.1 2.2 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation EphA2_TM PF14575.6 CDJ70422.1 - 2 9.4 3.5 2.6 9.0 2.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4175 PF13779.6 CDJ70422.1 - 5.7 4.7 12.6 9.8 3.9 12.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Dfp1_Him1_M PF08630.10 CDJ70422.1 - 7.3 6.8 7.3 7.1 6.9 4.1 2.0 1 1 1 2 2 2 0 Dfp1/Him1, central region MDM10 PF12519.8 CDJ70423.1 - 1.2 7.9 16.6 0.073 11.9 9.7 2.3 2 1 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 SRP-alpha_N PF04086.13 CDJ70424.1 - 0.092 12.6 3.4 0.11 12.4 3.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Med15 PF09606.10 CDJ70425.1 - 0.76 8.4 67.0 1 8.0 67.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SEA PF01390.20 CDJ70426.1 - 0.017 15.2 0.0 0.017 15.2 0.0 3.0 3 1 1 4 4 4 0 SEA domain DUF4148 PF13663.6 CDJ70426.1 - 1.5 9.1 34.1 0.94 9.7 1.2 5.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4148) Spt20 PF12090.8 CDJ70427.1 - 7.2 6.1 9.3 0.22 11.1 1.7 2.0 2 0 0 2 2 2 0 Spt20 family OST3_OST6 PF04756.13 CDJ70428.1 - 0.016 14.6 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 CDJ70428.1 - 0.075 13.0 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin cNMP_binding PF00027.29 CDJ70429.1 - 1.7e-29 101.7 0.3 6.3e-21 74.3 0.1 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF4366 PF14283.6 CDJ70429.1 - 0.15 12.1 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Memo PF01875.17 CDJ70430.1 - 2.9e-39 134.9 0.0 5.3e-39 134.0 0.0 1.4 1 1 0 1 1 1 1 Memo-like protein B12D PF06522.11 CDJ70431.1 - 0.0032 17.2 0.0 0.006 16.4 0.0 1.5 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RskA PF10099.9 CDJ70431.1 - 0.21 11.9 2.8 0.31 11.3 2.4 1.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ70431.1 - 6.1 6.4 13.3 6.8 6.2 0.3 2.0 2 0 0 2 2 2 0 Spt20 family Pex14_N PF04695.13 CDJ70432.1 - 0.043 14.5 10.0 0.11 13.1 4.4 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ECR1_N PF14382.6 CDJ70433.1 - 1.7e-07 30.9 0.1 3.4e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region PP2C PF00481.21 CDJ70434.1 - 1.8e-42 145.7 8.5 4.4e-35 121.5 0.1 4.1 4 1 0 4 4 4 3 Protein phosphatase 2C Dehydrin PF00257.19 CDJ70434.1 - 8.5 6.9 43.3 0.5 10.9 6.3 4.7 4 1 0 4 4 4 0 Dehydrin BAT2_N PF07001.11 CDJ70435.1 - 0.079 13.4 18.1 0.091 13.2 18.1 1.1 1 0 0 1 1 1 0 BAT2 N-terminus SpoIIP PF07454.11 CDJ70435.1 - 0.31 10.5 21.2 0.31 10.4 21.2 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TCP PF03634.13 CDJ70435.1 - 0.35 11.4 20.0 0.4 11.2 20.0 1.0 1 0 0 1 1 1 0 TCP family transcription factor AIF_C PF14721.6 CDJ70435.1 - 0.36 11.2 14.7 0.43 10.9 14.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CobT PF06213.12 CDJ70435.1 - 0.37 10.1 29.1 0.37 10.1 29.1 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFIIA PF03153.13 CDJ70435.1 - 0.51 10.3 43.5 0.55 10.2 43.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ70435.1 - 0.52 11.0 28.0 0.54 10.9 28.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pinin_SDK_memA PF04696.13 CDJ70435.1 - 0.61 10.2 37.2 0.67 10.0 37.2 1.0 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Connexin PF00029.19 CDJ70435.1 - 0.71 9.6 15.5 0.75 9.5 15.5 1.1 1 0 0 1 1 1 0 Connexin GNAT_acetyltr_2 PF13718.6 CDJ70435.1 - 0.88 8.9 12.2 0.95 8.8 12.2 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF4820 PF16091.5 CDJ70435.1 - 0.9 8.9 14.6 1.4 8.3 14.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Gti1_Pac2 PF09729.9 CDJ70435.1 - 1.1 9.3 17.6 1.1 9.3 17.6 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family DDHD PF02862.17 CDJ70435.1 - 1.1 9.3 18.0 1.1 9.3 18.0 1.1 1 0 0 1 1 1 0 DDHD domain Pal1 PF08316.11 CDJ70435.1 - 1.1 10.0 10.3 1.2 9.9 10.3 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein FYDLN_acid PF09538.10 CDJ70435.1 - 1.8 9.3 13.2 2.2 9.0 13.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CSG2 PF16965.5 CDJ70435.1 - 2 7.3 11.1 2.1 7.2 11.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Endostatin PF06482.11 CDJ70435.1 - 2.3 7.6 17.3 2.5 7.5 17.3 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin FHIPEP PF00771.20 CDJ70435.1 - 2.3 6.6 10.9 2.5 6.4 10.9 1.2 1 0 0 1 1 1 0 FHIPEP family Paf1 PF03985.13 CDJ70435.1 - 2.5 7.0 26.3 2.8 6.9 26.3 1.0 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 CDJ70435.1 - 2.6 6.7 25.9 2.6 6.7 25.9 1.0 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ70435.1 - 2.8 6.8 29.0 2.8 6.8 29.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ70435.1 - 2.8 6.1 31.1 2.8 6.1 31.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3408 PF11888.8 CDJ70435.1 - 3 8.0 22.1 3.6 7.7 22.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF5308 PF17233.2 CDJ70435.1 - 3 8.0 17.2 3.3 7.9 17.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Tim54 PF11711.8 CDJ70435.1 - 3.2 6.5 20.8 3.6 6.3 20.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 CDJ70435.1 - 3.6 6.5 14.4 3.7 6.4 14.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SspB PF04386.13 CDJ70435.1 - 3.6 7.4 17.4 4.1 7.3 17.4 1.1 1 0 0 1 1 1 0 Stringent starvation protein B CPSF100_C PF13299.6 CDJ70435.1 - 3.7 7.7 17.9 4.1 7.5 17.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CLN3 PF02487.17 CDJ70435.1 - 3.8 6.5 16.8 3.8 6.5 16.8 1.0 1 0 0 1 1 1 0 CLN3 protein MMU163 PF17119.5 CDJ70435.1 - 4.3 6.4 11.1 4.7 6.3 11.1 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Baculo_PP31 PF05311.11 CDJ70435.1 - 4.6 6.7 17.8 4.6 6.7 17.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Afi1 PF07792.12 CDJ70435.1 - 4.6 7.7 19.0 5.4 7.5 19.0 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RR_TM4-6 PF06459.12 CDJ70435.1 - 4.6 7.0 23.0 4.7 7.0 23.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 CDJ70435.1 - 5 4.9 23.3 5.2 4.9 23.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 CDJ70435.1 - 5.1 6.0 21.0 5.2 6.0 21.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 UPF0560 PF10577.9 CDJ70435.1 - 5.2 5.4 29.5 5.3 5.4 29.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Peptidase_U57 PF05582.12 CDJ70435.1 - 5.2 6.2 14.6 5.8 6.1 14.6 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF3381 PF11861.8 CDJ70435.1 - 5.3 6.8 28.9 5.7 6.7 28.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) TFB6 PF17110.5 CDJ70435.1 - 5.3 6.7 14.5 5.9 6.6 14.5 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Band_3_cyto PF07565.13 CDJ70435.1 - 5.6 6.7 19.9 6.3 6.5 19.9 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4746 PF15928.5 CDJ70435.1 - 5.6 6.3 19.0 6.6 6.1 19.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CCDC53 PF10152.9 CDJ70435.1 - 5.8 7.3 22.9 6.7 7.1 22.9 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FAM176 PF14851.6 CDJ70435.1 - 6.2 6.5 15.2 7.6 6.2 15.2 1.1 1 0 0 1 1 1 0 FAM176 family EPL1 PF10513.9 CDJ70435.1 - 6.3 7.2 22.3 8.1 6.8 22.3 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF2126 PF09899.9 CDJ70435.1 - 6.9 4.6 15.9 7.3 4.5 15.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF1980 PF09323.10 CDJ70435.1 - 7.1 6.5 17.0 7.7 6.4 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) FAM60A PF15396.6 CDJ70435.1 - 7.2 6.6 15.9 8.1 6.4 15.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2828 PF11443.8 CDJ70435.1 - 7.2 4.6 22.2 7.4 4.5 22.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Bul1_N PF04425.12 CDJ70435.1 - 7.3 5.2 16.4 7.3 5.2 16.4 1.0 1 0 0 1 1 1 0 Bul1 N terminus MDM10 PF12519.8 CDJ70435.1 - 7.5 5.3 19.5 7.8 5.2 19.5 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SID-1_RNA_chan PF13965.6 CDJ70435.1 - 7.5 4.8 13.0 8.1 4.7 13.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PPL5 PF18168.1 CDJ70435.1 - 7.6 5.7 16.8 7.6 5.7 16.8 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S15 PF02129.18 CDJ70435.1 - 7.7 6.0 15.7 8.3 5.9 15.7 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) EOS1 PF12326.8 CDJ70435.1 - 7.9 6.4 14.7 8.8 6.2 14.7 1.2 1 0 0 1 1 1 0 N-glycosylation protein Neur_chan_memb PF02932.16 CDJ70435.1 - 8.2 6.4 16.7 9 6.3 16.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 CDJ70435.1 - 8.4 5.1 21.0 9 5.0 21.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Membralin PF09746.9 CDJ70435.1 - 8.8 5.2 13.7 8.6 5.3 13.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein BORG_CEP PF14957.6 CDJ70435.1 - 9.4 7.4 14.4 9.8 7.4 14.4 1.1 1 0 0 1 1 1 0 Cdc42 effector ALMT PF11744.8 CDJ70435.1 - 9.4 4.9 17.6 9.6 4.9 17.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3446 PF11928.8 CDJ70436.1 - 0.0051 17.1 4.5 0.0051 17.1 4.5 4.4 4 0 0 4 4 4 1 Early growth response N-terminal domain RskA PF10099.9 CDJ70436.1 - 0.0085 16.4 16.8 0.0085 16.4 16.8 5.5 3 2 2 5 5 5 2 Anti-sigma-K factor rskA DUF4667 PF15700.5 CDJ70436.1 - 0.027 14.6 14.4 0.75 9.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ70436.1 - 0.048 13.7 51.7 0.018 15.1 23.5 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Dimer_Tnp_hAT PF05699.14 CDJ70436.1 - 0.12 12.2 0.7 0.26 11.1 0.7 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Suf PF05843.14 CDJ70436.1 - 0.5 10.3 21.4 0.31 11.0 10.7 2.6 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) CAF1 PF04857.20 CDJ70436.1 - 2.3 7.3 9.5 7.3 5.7 6.0 2.1 2 0 0 2 2 2 0 CAF1 family ribonuclease Zip PF02535.22 CDJ70436.1 - 3.4 6.8 6.1 0.18 11.0 0.1 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ70436.1 - 4.8 5.8 19.8 3.1 6.5 13.8 2.4 3 0 0 3 3 3 0 Presenilin Endonuc_Holl PF10107.9 CDJ70437.1 - 0.01 15.7 2.8 0.01 15.7 2.8 2.2 2 0 0 2 2 2 2 Endonuclease related to archaeal Holliday junction resolvase TFIIA PF03153.13 CDJ70437.1 - 0.012 15.6 62.3 0.18 11.7 12.0 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ70437.1 - 9.8 5.6 39.7 4.7 6.7 27.0 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Kelch_1 PF01344.25 CDJ70439.1 - 1.1e-19 69.7 0.0 2.2e-10 40.0 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDJ70439.1 - 1.9e-09 37.5 0.0 2.7e-06 27.4 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 CDJ70439.1 - 0.0015 18.4 0.0 0.0093 15.9 0.0 2.3 2 0 0 2 2 2 1 Kelch motif TFIIA PF03153.13 CDJ70439.1 - 0.013 15.6 40.2 0.013 15.6 40.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ70439.1 - 0.028 14.0 15.4 0.044 13.3 15.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PIP5K PF01504.18 CDJ70439.1 - 0.048 12.9 4.9 0.076 12.2 4.9 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Kelch_5 PF13854.6 CDJ70439.1 - 0.11 12.5 0.0 26 4.9 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Presenilin PF01080.17 CDJ70439.1 - 0.16 10.7 20.0 0.3 9.8 20.0 1.4 1 0 0 1 1 1 0 Presenilin Kelch_3 PF13415.6 CDJ70439.1 - 0.25 11.7 2.2 0.32 11.4 0.0 2.4 2 0 0 2 2 1 0 Galactose oxidase, central domain DUF572 PF04502.13 CDJ70439.1 - 0.29 10.7 18.2 0.58 9.7 18.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3537 PF12056.8 CDJ70439.1 - 0.45 9.3 4.8 0.69 8.7 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) CDC45 PF02724.14 CDJ70439.1 - 0.56 8.4 12.3 0.74 8.0 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein XAP5 PF04921.14 CDJ70439.1 - 0.8 9.5 9.8 1.3 8.8 9.8 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Neur_chan_memb PF02932.16 CDJ70439.1 - 0.94 9.5 10.8 2 8.4 10.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 CDJ70439.1 - 1.3 6.1 14.2 2 5.4 14.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2126 PF09899.9 CDJ70439.1 - 1.4 6.9 9.9 2 6.4 9.9 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SLC12 PF03522.15 CDJ70439.1 - 1.6 7.6 20.1 2.4 7.1 20.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ70439.1 - 2.6 7.8 19.7 5.1 6.8 19.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3295 PF11702.8 CDJ70439.1 - 5.2 6.3 21.6 0.074 12.4 12.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) Sec62 PF03839.16 CDJ70439.1 - 5.6 6.4 13.1 8.3 5.8 13.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Nop53 PF07767.11 CDJ70439.1 - 9.9 5.4 23.7 16 4.7 23.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Chromo PF00385.24 CDJ70441.1 - 2.7e-14 52.8 0.0 5.5e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Conotoxin PF02950.17 CDJ70443.1 - 7.4 7.7 0.0 7.4 7.7 0.0 7.6 5 1 2 7 7 7 0 Conotoxin SR-25 PF10500.9 CDJ70444.1 - 7.5e-05 22.4 14.5 7.5e-05 22.4 14.5 2.9 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ70444.1 - 0.0029 17.9 18.1 0.0029 17.9 18.1 6.5 3 1 1 4 4 4 1 Anti-sigma-K factor rskA Utp14 PF04615.13 CDJ70444.1 - 0.013 14.1 58.0 0.019 13.6 58.0 1.2 1 0 0 1 1 1 0 Utp14 protein Conotoxin PF02950.17 CDJ70444.1 - 0.017 16.2 5.2 0.017 16.2 5.2 5.7 3 1 0 3 3 3 0 Conotoxin Ribosomal_60s PF00428.19 CDJ70444.1 - 0.99 10.0 13.2 0.25 12.0 7.4 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Amidohydro_2 PF04909.14 CDJ70444.1 - 8.3 6.1 7.3 16 5.1 7.3 1.6 1 0 0 1 1 1 0 Amidohydrolase TFIIA PF03153.13 CDJ70445.1 - 0.00025 21.2 19.0 0.00025 21.2 19.0 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit FKBP_C PF00254.28 CDJ70445.1 - 0.00075 19.8 0.0 0.01 16.1 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase SR-25 PF10500.9 CDJ70445.1 - 0.014 15.0 24.9 0.014 15.0 24.9 2.9 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ70445.1 - 0.068 13.1 22.2 0.12 12.2 20.3 2.0 2 0 0 2 2 2 0 SPX domain Spt20 PF12090.8 CDJ70445.1 - 1.4 8.4 33.2 0.55 9.8 29.1 2.0 2 0 0 2 2 2 0 Spt20 family DUF2369 PF10179.9 CDJ70445.1 - 2.2 8.7 10.4 63 4.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) Ndc1_Nup PF09531.10 CDJ70445.1 - 7.9 5.0 22.7 0.83 8.3 14.3 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Dopey_N PF04118.14 CDJ70446.1 - 1e-26 93.8 0.3 1e-26 93.8 0.3 3.5 4 0 0 4 4 4 1 Dopey, N-terminal HTH_Tnp_1 PF01527.20 CDJ70446.1 - 0.0016 18.7 0.3 0.011 16.1 0.3 2.6 1 0 0 1 1 1 1 Transposase Bromodomain PF00439.25 CDJ70447.1 - 5.2e-13 48.9 0.1 2e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Bromodomain DUF572 PF04502.13 CDJ70449.1 - 7.5 6.1 12.0 4 7.0 1.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Chorion_2 PF03964.15 CDJ70450.1 - 0.00035 21.4 3.2 0.00035 21.4 3.2 2.8 3 0 0 3 3 3 2 Chorion family 2 FumaraseC_C PF10415.9 CDJ70450.1 - 0.5 10.8 2.7 1 9.8 2.7 1.5 1 0 0 1 1 1 0 Fumarase C C-terminus Silic_transp PF03842.13 CDJ70450.1 - 0.82 7.9 4.1 1.2 7.3 4.1 1.2 1 0 0 1 1 1 0 Silicon transporter Ribosomal_60s PF00428.19 CDJ70450.1 - 4.9 7.8 16.5 1.1 9.9 6.6 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ70451.1 - 0.00061 19.5 6.7 0.00061 19.5 6.7 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ70451.1 - 0.0051 15.8 4.8 0.0052 15.8 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ70451.1 - 0.0061 16.6 6.2 0.0061 16.6 6.2 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ70451.1 - 0.0093 14.7 7.9 0.01 14.6 7.9 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Orf78 PF06024.12 CDJ70451.1 - 0.045 14.0 0.1 0.064 13.6 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) DUF2116 PF09889.9 CDJ70451.1 - 9.7 6.3 9.4 33 4.6 9.4 2.1 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RRM_1 PF00076.22 CDJ70452.1 - 7.3e-07 28.9 0.3 1.3e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4611 PF15387.6 CDJ70453.1 - 0.0081 16.4 1.0 0.0081 16.4 1.0 3.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4611) RskA PF10099.9 CDJ70453.1 - 0.0085 16.4 11.9 0.0085 16.4 11.9 2.9 1 1 1 2 2 2 1 Anti-sigma-K factor rskA MMR1 PF08505.10 CDJ70453.1 - 0.37 11.0 38.1 0.11 12.8 23.3 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 CDJ70453.1 - 0.77 8.4 43.4 0.079 11.7 29.5 2.0 2 0 0 2 2 2 0 Presenilin DUF3807 PF12720.7 CDJ70453.1 - 2 8.6 50.7 0.59 10.4 35.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) AAA_11 PF13086.6 CDJ70453.1 - 3 7.6 37.0 0.65 9.7 4.0 2.2 2 0 0 2 2 2 0 AAA domain NPR3 PF03666.13 CDJ70453.1 - 4.1 6.1 31.9 0.24 10.2 22.5 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_S64 PF08192.11 CDJ70453.1 - 4.2 5.7 27.5 6.3 5.2 27.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 ADP_ribosyl_GH PF03747.14 CDJ70453.1 - 5.9 6.5 9.2 0.31 10.7 3.3 1.8 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase BORG_CEP PF14957.6 CDJ70453.1 - 6.2 8.0 30.9 7.5 7.7 3.2 2.3 2 0 0 2 2 2 0 Cdc42 effector DUF2722 PF10846.8 CDJ70455.1 - 0.00078 18.5 25.8 0.035 13.1 2.9 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ70455.1 - 0.006 16.2 4.5 0.006 16.2 4.5 3.4 3 1 0 3 3 3 2 Spt20 family RAP PF08373.10 CDJ70455.1 - 0.01 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 RAP domain Gp49 PF05973.14 CDJ70455.1 - 0.064 13.4 0.2 0.25 11.5 0.0 2.2 2 1 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) OHA PF14418.6 CDJ70456.1 - 3.1e-18 65.4 0.0 9.5e-18 63.8 0.0 1.8 1 0 0 1 1 1 1 OST-HTH Associated domain Spt20 PF12090.8 CDJ70456.1 - 0.0016 18.1 3.5 0.0016 18.1 3.5 5.3 3 1 0 4 4 4 1 Spt20 family CLN3 PF02487.17 CDJ70457.1 - 0.00018 20.7 0.6 0.00042 19.5 0.6 1.6 1 0 0 1 1 1 1 CLN3 protein Phage_holin_3_6 PF07332.11 CDJ70457.1 - 0.0012 18.8 1.8 0.0012 18.8 1.8 5.5 3 2 1 4 4 2 1 Putative Actinobacterial Holin-X, holin superfamily III Ctr PF04145.15 CDJ70457.1 - 0.0026 18.4 10.6 0.043 14.4 10.6 2.8 1 1 0 1 1 1 1 Ctr copper transporter family CitMHS PF03600.16 CDJ70457.1 - 0.0044 16.3 15.8 0.0019 17.5 3.2 3.0 1 1 1 2 2 2 1 Citrate transporter Borrelia_P83 PF05262.11 CDJ70457.1 - 0.0059 15.2 0.4 0.0093 14.5 0.4 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein SPX PF03105.19 CDJ70457.1 - 0.0069 16.3 11.8 0.011 15.7 11.8 1.2 1 0 0 1 1 1 1 SPX domain TFIIA PF03153.13 CDJ70457.1 - 0.011 15.7 35.1 0.13 12.2 29.8 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Wzy_C PF04932.15 CDJ70457.1 - 0.013 15.2 0.0 0.07 12.8 0.0 2.2 2 0 0 2 2 2 0 O-Antigen ligase O-antigen_lig PF13425.6 CDJ70457.1 - 0.029 13.2 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Herpes_glycop PF01528.16 CDJ70457.1 - 0.052 12.4 0.2 0.088 11.6 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein M MFS_Mycoplasma PF07672.13 CDJ70457.1 - 0.13 11.5 0.1 0.56 9.4 0.1 2.0 2 0 0 2 2 2 0 Mycoplasma MFS transporter Macoilin PF09726.9 CDJ70457.1 - 0.17 10.4 6.8 0.32 9.5 6.8 1.4 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 CDJ70457.1 - 0.42 8.5 6.9 0.61 7.9 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec62 PF03839.16 CDJ70457.1 - 1.3 8.5 4.7 2.7 7.4 4.7 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 COPI_assoc PF08507.10 CDJ70457.1 - 2.7 8.1 8.6 1.2 9.2 2.8 2.9 2 1 0 2 2 2 0 COPI associated protein PAS_5 PF07310.13 CDJ70457.1 - 4 7.2 6.5 0.74 9.6 0.2 2.2 2 0 0 2 2 2 0 PAS domain DUF2140 PF09911.9 CDJ70457.1 - 4.9 6.7 7.1 13 5.2 7.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF4171 PF13775.6 CDJ70457.1 - 5.1 7.6 18.1 0.26 11.7 3.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4171) Neur_chan_memb PF02932.16 CDJ70457.1 - 7 6.6 8.1 14 5.6 8.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PIG-U PF06728.13 CDJ70457.1 - 7.7 5.4 10.6 60 2.5 0.1 3.2 1 1 1 2 2 2 0 GPI transamidase subunit PIG-U DUF775 PF05603.12 CDJ70457.1 - 8.3 5.9 17.3 0.53 9.8 10.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) ADK PF00406.22 CDJ70459.1 - 5.8e-11 42.7 3.3 2.7e-10 40.6 0.4 2.7 2 1 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 CDJ70459.1 - 4.5e-07 30.4 6.4 7e-06 26.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF2722 PF10846.8 CDJ70459.1 - 0.00094 18.2 19.9 0.00094 18.2 19.9 2.4 2 1 0 2 2 1 1 Protein of unknown function (DUF2722) PRC2_HTH_1 PF18118.1 CDJ70459.1 - 0.0017 19.1 4.0 0.37 11.6 3.1 2.5 2 0 0 2 2 2 1 Polycomb repressive complex 2 tri-helical domain AAA_33 PF13671.6 CDJ70459.1 - 0.002 18.3 1.1 0.002 18.3 1.1 2.5 2 0 0 2 2 2 1 AAA domain U1snRNP70_N PF12220.8 CDJ70459.1 - 0.0027 18.3 10.7 0.0027 18.3 10.7 2.8 2 1 0 2 2 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Spt20 PF12090.8 CDJ70459.1 - 0.0048 16.5 48.6 0.0084 15.7 3.0 2.2 2 0 0 2 2 2 1 Spt20 family AAA_18 PF13238.6 CDJ70459.1 - 0.018 15.6 0.7 0.16 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Peroxin-13_N PF04088.13 CDJ70459.1 - 0.03 14.6 1.4 0.03 14.6 1.4 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Dpy-30 PF05186.13 CDJ70459.1 - 0.035 13.8 0.9 0.071 12.8 0.9 1.5 1 0 0 1 1 1 0 Dpy-30 motif MecA PF05389.12 CDJ70459.1 - 0.065 12.8 12.8 0.021 14.5 6.9 2.2 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) CobT PF06213.12 CDJ70459.1 - 0.067 12.6 20.8 0.022 14.2 14.0 2.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Cytidylate_kin2 PF13189.6 CDJ70459.1 - 0.13 12.4 1.0 0.83 9.8 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family RNA_lig_T4_1 PF09511.10 CDJ70459.1 - 0.14 12.0 3.6 0.22 11.3 3.6 1.4 1 0 0 1 1 1 0 RNA ligase Radial_spoke PF04712.12 CDJ70459.1 - 0.17 10.8 15.5 0.025 13.5 8.3 2.0 2 0 0 2 2 2 0 Radial spokehead-like protein EFTUD2 PF16004.5 CDJ70459.1 - 0.19 12.3 12.3 0.11 13.1 6.1 2.3 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus MDM10 PF12519.8 CDJ70459.1 - 0.23 10.3 6.7 0.34 9.7 6.7 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Ytp1 PF10355.9 CDJ70459.1 - 0.27 10.4 0.8 0.45 9.7 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) MPM1 PF17234.2 CDJ70459.1 - 0.31 11.3 13.2 0.062 13.5 5.1 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF3807 PF12720.7 CDJ70459.1 - 0.66 10.2 20.9 0.093 13.0 9.9 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF3807) MAT1 PF06391.13 CDJ70459.1 - 0.88 9.4 24.0 2 8.2 14.5 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF4834 PF16118.5 CDJ70459.1 - 1.1 10.3 21.0 15 6.6 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CCDC53 PF10152.9 CDJ70459.1 - 1.2 9.6 20.3 0.67 10.4 10.7 2.4 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Peptidase_S49_N PF08496.10 CDJ70459.1 - 1.3 9.0 17.1 3.6 7.6 10.6 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4611 PF15387.6 CDJ70459.1 - 1.7 8.9 18.2 0.22 11.8 9.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) GerA PF03323.13 CDJ70459.1 - 1.8 6.9 5.2 5.2 5.4 0.0 2.0 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF2367 PF10164.9 CDJ70459.1 - 1.9 9.1 7.8 2.3 8.8 3.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) RICTOR_N PF14664.6 CDJ70459.1 - 2.2 7.2 7.3 0.39 9.7 3.6 1.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Peptidase_U57 PF05582.12 CDJ70459.1 - 2.2 7.5 9.9 0.84 8.8 4.1 2.2 2 0 0 2 2 2 0 YabG peptidase U57 Het-C PF07217.11 CDJ70459.1 - 2.8 6.4 13.4 0.77 8.2 8.4 1.9 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C ORC_WH_C PF18137.1 CDJ70459.1 - 3.1 7.9 11.6 2.2 8.3 6.3 2.3 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Baculo_PP31 PF05311.11 CDJ70459.1 - 3.3 7.1 13.7 0.46 9.9 6.6 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) CDH1_2_SANT_HL1 PF18375.1 CDJ70459.1 - 3.3 8.4 7.0 2.3 9.0 2.4 2.9 3 0 0 3 3 2 0 CDH1/2 SANT-Helical linker 1 Folate_carrier PF01770.18 CDJ70459.1 - 3.9 6.1 4.7 0.55 8.9 1.1 1.5 2 0 0 2 2 2 0 Reduced folate carrier CsiV PF10972.8 CDJ70459.1 - 4 7.1 23.8 0.031 14.0 0.7 2.3 2 0 0 2 2 2 0 Peptidoglycan-binding protein, CsiV FAM60A PF15396.6 CDJ70459.1 - 4.3 7.3 12.6 0.55 10.2 4.8 2.3 3 0 0 3 3 2 0 Protein Family FAM60A DUF4228 PF14009.6 CDJ70459.1 - 4.4 7.6 19.0 2.5 8.5 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4228) TCP PF03634.13 CDJ70459.1 - 5.1 7.6 22.7 0.27 11.8 10.2 2.9 3 0 0 3 3 3 0 TCP family transcription factor Pex14_N PF04695.13 CDJ70459.1 - 6 7.5 32.8 0.1 13.3 15.4 2.6 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.6 CDJ70459.1 - 6.2 6.5 8.3 1.4 8.6 3.5 2.2 2 0 0 2 2 2 0 FAM176 family hDGE_amylase PF14701.6 CDJ70459.1 - 6.4 5.8 12.3 14 4.6 7.9 2.1 1 1 1 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Pinin_SDK_memA PF04696.13 CDJ70459.1 - 7.2 6.7 34.2 0.42 10.7 20.4 2.8 3 0 0 3 3 2 0 pinin/SDK/memA/ protein conserved region MID_MedPIWI PF18296.1 CDJ70459.1 - 8.1 6.2 23.4 42 3.8 22.1 2.3 1 1 1 2 2 2 0 MID domain of medPIWI V_ATPase_I PF01496.19 CDJ70459.1 - 8.3 4.2 15.3 0.82 7.5 8.4 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Tim54 PF11711.8 CDJ70459.1 - 9 5.0 12.8 3.1 6.5 8.7 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4200 PF13863.6 CDJ70460.1 - 1.2e-12 48.3 22.0 1.2e-12 48.3 22.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) Kinesin PF00225.23 CDJ70462.1 - 7.5e-31 107.3 0.2 8.8e-31 107.0 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ70462.1 - 1.1e-18 67.6 0.0 1.3e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 CDJ70462.1 - 0.0011 18.3 0.1 0.0017 17.6 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 CDJ70462.1 - 0.024 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PBP_like_2 PF12849.7 CDJ70462.1 - 0.037 13.7 0.1 0.041 13.5 0.1 1.1 1 0 0 1 1 1 0 PBP superfamily domain PhoH PF02562.16 CDJ70462.1 - 0.086 12.3 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 CDJ70462.1 - 0.3 11.3 1.2 3.1 8.1 0.5 2.1 1 1 1 2 2 2 0 AAA domain Prokineticin PF06607.11 CDJ70463.1 - 0.063 13.6 0.5 0.12 12.7 0.5 1.4 1 0 0 1 1 1 0 Prokineticin RskA PF10099.9 CDJ70463.1 - 0.63 10.3 13.1 2.7 8.3 7.0 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Tweety PF04906.13 CDJ70463.1 - 4 6.0 10.0 5 5.7 8.8 1.8 1 1 0 1 1 1 0 Tweety Spt20 PF12090.8 CDJ70464.1 - 4.9e-05 23.1 31.5 0.00013 21.6 15.8 2.4 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ70464.1 - 0.0017 17.4 13.8 0.0017 17.4 13.8 3.2 2 1 0 3 3 3 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ70464.1 - 0.0075 16.6 20.3 0.0075 16.6 20.3 5.0 2 2 2 4 4 2 1 Anti-sigma-K factor rskA TERB2 PF15101.6 CDJ70464.1 - 0.02 14.9 7.4 0.02 14.9 7.4 2.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Beta_propel PF09826.9 CDJ70464.1 - 0.05 12.5 0.2 0.09 11.6 0.2 1.4 1 0 0 1 1 1 0 Beta propeller domain Exo_endo_phos PF03372.23 CDJ70464.1 - 0.14 11.7 0.0 0.5 9.8 0.0 1.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family eIF-3_zeta PF05091.12 CDJ70464.1 - 0.21 10.5 9.2 0.012 14.6 2.6 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ70464.1 - 0.3 12.1 15.5 0.8 10.7 9.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Tau95_N PF17682.1 CDJ70464.1 - 0.44 10.7 8.5 0.04 14.1 2.5 2.1 2 0 0 2 2 2 0 Tau95 Triple barrel domain Peptidase_S49_N PF08496.10 CDJ70464.1 - 0.45 10.6 8.6 0.19 11.8 3.4 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MPM1 PF17234.2 CDJ70464.1 - 0.66 10.2 10.9 0.44 10.8 5.7 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 NPR1_interact PF15699.5 CDJ70464.1 - 0.76 10.4 11.1 0.21 12.2 4.1 2.7 2 0 0 2 2 2 0 NPR1 interacting MMR1 PF08505.10 CDJ70464.1 - 1.2 9.4 16.8 0.92 9.8 7.3 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein TFIIIC_sub6 PF10419.9 CDJ70464.1 - 1.7 8.5 9.1 0.22 11.4 5.2 1.7 2 1 0 2 2 2 0 TFIIIC subunit triple barrel domain DUF1980 PF09323.10 CDJ70464.1 - 1.8 8.4 5.3 0.68 9.8 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Activator_LAG-3 PF11498.8 CDJ70464.1 - 2.4 7.0 39.4 1.2 8.0 25.3 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 RNA_pol_Rbc25 PF08292.12 CDJ70464.1 - 3.1 8.1 9.0 0.81 9.9 1.7 2.5 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 TFIIA PF03153.13 CDJ70464.1 - 3.2 7.6 60.9 1.4e+02 2.2 60.9 2.1 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAP65_ASE1 PF03999.12 CDJ70464.1 - 4 6.0 17.6 0.37 9.5 9.1 2.1 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) FAM176 PF14851.6 CDJ70464.1 - 4.9 6.8 7.8 3.4 7.3 4.0 2.3 2 0 0 2 2 2 0 FAM176 family UPF0560 PF10577.9 CDJ70464.1 - 5.8 5.3 18.7 0.42 9.1 8.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 SUIM_assoc PF16619.5 CDJ70466.1 - 1.4 9.0 31.4 0.1 12.7 9.7 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ70467.1 - 0.0012 19.2 2.0 0.0012 19.2 2.0 11.1 4 3 5 9 9 9 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ70467.1 - 0.0073 16.3 1.9 0.0073 16.3 1.9 12.3 9 3 1 10 10 10 6 Unstructured region C-term to UIM in Ataxin3 Aminotran_5 PF00266.19 CDJ70468.1 - 4e-36 124.8 0.0 3.2e-22 79.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 CDJ70468.1 - 0.0079 15.4 0.0 0.087 12.0 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CDJ70468.1 - 0.087 11.3 0.1 0.14 10.7 0.1 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CCSAP PF15748.5 CDJ70469.1 - 0.077 13.2 12.8 0.09 12.9 12.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TFIIA PF03153.13 CDJ70469.1 - 0.079 12.9 21.9 0.086 12.8 21.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 CDJ70469.1 - 0.083 12.1 21.0 0.11 11.6 21.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SelP_N PF04592.14 CDJ70469.1 - 0.12 11.8 7.3 0.16 11.4 7.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PIP5K PF01504.18 CDJ70469.1 - 0.17 11.1 3.8 0.22 10.7 3.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Striatin PF08232.12 CDJ70469.1 - 0.38 11.3 9.0 0.48 11.0 9.0 1.1 1 0 0 1 1 1 0 Striatin family NPR3 PF03666.13 CDJ70469.1 - 0.55 9.0 7.6 0.63 8.8 7.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ70469.1 - 0.63 8.7 11.9 0.72 8.6 11.9 1.0 1 0 0 1 1 1 0 Presenilin DUF5470 PF17564.2 CDJ70469.1 - 0.7 10.1 3.5 1.2 9.4 3.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5470) PAT1 PF09770.9 CDJ70469.1 - 0.87 7.8 14.8 0.92 7.7 14.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CCDC53 PF10152.9 CDJ70469.1 - 0.92 9.9 12.0 1.2 9.5 12.0 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Ndc1_Nup PF09531.10 CDJ70469.1 - 1.3 7.6 11.1 1.4 7.5 11.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mitofilin PF09731.9 CDJ70469.1 - 1.5 7.6 11.7 1.7 7.4 11.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SOG2 PF10428.9 CDJ70469.1 - 1.7 7.7 16.6 2 7.6 16.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein RR_TM4-6 PF06459.12 CDJ70469.1 - 2 8.1 6.2 2.4 7.9 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 CDJ70469.1 - 2.3 6.3 9.9 2.5 6.1 9.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 CDJ70469.1 - 2.3 5.2 12.3 2.6 5.1 12.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDJ70469.1 - 3 6.3 9.8 3.3 6.1 9.8 1.0 1 0 0 1 1 1 0 Macoilin family Serinc PF03348.15 CDJ70469.1 - 3.1 6.6 5.7 3.8 6.3 5.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hep_59 PF07052.11 CDJ70469.1 - 3.7 8.4 10.5 14 6.5 10.5 1.9 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 MTBP_C PF14920.6 CDJ70469.1 - 5 6.8 17.3 6.6 6.4 17.3 1.1 1 0 0 1 1 1 0 MDM2-binding Spc7_N PF15402.6 CDJ70469.1 - 7.3 4.7 16.7 8.6 4.5 16.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Band_3_cyto PF07565.13 CDJ70469.1 - 7.5 6.3 8.9 10 5.8 8.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SR-25 PF10500.9 CDJ70469.1 - 8.5 5.9 23.9 30 4.1 24.0 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ70469.1 - 9.1 6.8 15.9 12 6.4 15.9 1.1 1 0 0 1 1 1 0 TCP family transcription factor GTP_EFTU PF00009.27 CDJ70470.1 - 0.00013 21.6 2.4 0.0017 17.9 2.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TFIIA PF03153.13 CDJ70471.1 - 0.0075 16.3 28.0 0.013 15.5 28.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ70471.1 - 0.053 12.2 30.9 0.069 11.8 30.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Arb1 PF09692.10 CDJ70471.1 - 0.058 12.6 2.7 0.078 12.1 2.7 1.1 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF4834 PF16118.5 CDJ70471.1 - 0.064 14.2 6.6 0.56 11.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) FAM60A PF15396.6 CDJ70471.1 - 0.12 12.3 2.1 0.19 11.7 2.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A RskA PF10099.9 CDJ70471.1 - 0.15 12.4 32.9 0.39 11.0 31.9 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Ndc1_Nup PF09531.10 CDJ70471.1 - 0.23 10.1 7.7 0.25 10.0 7.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VIT1 PF01988.19 CDJ70471.1 - 0.25 11.2 8.3 1.1 9.1 0.7 2.3 1 1 1 2 2 2 0 VIT family DUF2207 PF09972.9 CDJ70471.1 - 0.3 9.8 1.2 7 5.3 0.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Hydin_ADK PF17213.3 CDJ70471.1 - 0.59 10.4 10.3 0.93 9.7 9.5 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF4366 PF14283.6 CDJ70471.1 - 0.69 9.9 4.8 1.2 9.2 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) PDGF_N PF04692.13 CDJ70471.1 - 0.76 10.6 8.3 0.23 12.2 1.7 2.3 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region Thioredoxin_16 PF18569.1 CDJ70471.1 - 0.99 9.6 4.0 0.32 11.2 0.3 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain Sin_N PF04801.13 CDJ70471.1 - 2.5 7.2 17.8 4.1 6.5 17.8 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region Presenilin PF01080.17 CDJ70471.1 - 2.9 6.6 8.1 4 6.1 8.1 1.1 1 0 0 1 1 1 0 Presenilin BAF1_ABF1 PF04684.13 CDJ70471.1 - 3.7 6.5 11.1 5.2 6.0 11.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2722 PF10846.8 CDJ70472.1 - 1.1 8.1 21.0 0.45 9.4 8.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF5542 PF17696.1 CDJ70472.1 - 1.5 9.0 14.5 0.82 9.8 4.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5542) Presenilin PF01080.17 CDJ70472.1 - 2.6 6.7 7.2 3.6 6.3 7.2 1.2 1 0 0 1 1 1 0 Presenilin ANAPC_CDC26 PF10471.9 CDJ70472.1 - 4.1 8.3 25.3 0.6 11.0 7.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 CNDH2_N PF06278.11 CDJ70472.1 - 4.3 7.6 9.8 0.42 10.8 3.2 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal p25-alpha PF05517.12 CDJ70473.1 - 3.3e-32 111.8 0.3 3.8e-32 111.6 0.3 1.0 1 0 0 1 1 1 1 p25-alpha SurA_N PF09312.11 CDJ70473.1 - 0.013 15.6 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 SurA N-terminal domain MobL PF18555.1 CDJ70473.1 - 0.065 12.5 0.1 0.08 12.2 0.1 1.1 1 0 0 1 1 1 0 MobL relaxases RHH_4 PF13467.6 CDJ70473.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain EF-hand_7 PF13499.6 CDJ70473.1 - 0.11 13.0 0.0 1.4 9.4 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair SET PF00856.28 CDJ70474.1 - 2.8e-07 31.1 15.7 1.2e-06 29.0 6.7 3.3 2 1 0 2 2 2 1 SET domain RskA PF10099.9 CDJ70474.1 - 0.0015 18.8 0.0 0.0015 18.8 0.0 5.5 2 2 1 4 4 2 2 Anti-sigma-K factor rskA DUF4667 PF15700.5 CDJ70474.1 - 0.011 15.8 1.9 0.011 15.8 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) DUF4228 PF14009.6 CDJ70474.1 - 0.051 14.0 10.3 1.3 9.3 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4228) RHS PF03527.14 CDJ70474.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 RHS protein DUF2126 PF09899.9 CDJ70474.1 - 0.46 8.5 2.6 4.8 5.1 1.0 2.0 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) DUF1980 PF09323.10 CDJ70474.1 - 0.59 10.0 3.4 14 5.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Spt20 PF12090.8 CDJ70474.1 - 1.5 8.4 46.4 0.61 9.7 18.6 2.1 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ70474.1 - 3.2 7.3 24.0 0.12 11.9 7.6 3.0 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein eIF-3_zeta PF05091.12 CDJ70474.1 - 5.7 5.8 14.3 3.9 6.3 3.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FHIPEP PF00771.20 CDJ70474.1 - 8.4 4.7 7.7 2.3 6.6 0.6 2.1 2 0 0 2 2 2 0 FHIPEP family eIF_4EBP PF05456.11 CDJ70474.1 - 8.9 6.3 9.6 7.4 6.6 0.6 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Orf78 PF06024.12 CDJ70474.1 - 9.5 6.6 7.0 10 6.5 0.1 2.4 2 0 0 2 2 2 0 Orf78 (ac78) ISP3_C PF18045.1 CDJ70475.1 - 1.2e-35 121.7 0.0 1.5e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 ISP3 C-terminal ISP1_C PF18161.1 CDJ70475.1 - 3.8e-22 78.3 0.0 4.7e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 ISP1 C-terminal SelK_SelG PF10961.8 CDJ70475.1 - 0.015 15.9 4.2 0.028 15.0 4.2 1.5 1 1 0 1 1 1 0 Selenoprotein SelK_SelG SR-25 PF10500.9 CDJ70475.1 - 6.8 6.2 10.3 13 5.3 10.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cpn60_TCP1 PF00118.24 CDJ70477.1 - 8.5e-38 130.2 0.9 2.8e-26 92.2 0.1 2.8 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family CHD5 PF04420.14 CDJ70478.1 - 6.4e-07 29.4 8.9 1.3e-06 28.4 8.9 1.5 1 0 0 1 1 1 1 CHD5-like protein Lin-8 PF03353.15 CDJ70478.1 - 0.0053 16.4 9.0 0.0095 15.5 9.0 1.3 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist FapA PF03961.13 CDJ70478.1 - 0.33 9.5 4.0 0.43 9.1 4.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TFIIA PF03153.13 CDJ70478.1 - 0.79 9.7 22.0 1.3 8.9 22.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ70478.1 - 1.1 7.1 7.0 1.4 6.7 7.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S46 PF10459.9 CDJ70478.1 - 1.2 7.7 5.9 1.5 7.4 5.9 1.1 1 0 0 1 1 1 0 Peptidase S46 SPX PF03105.19 CDJ70478.1 - 1.5 8.7 23.0 23 4.8 23.5 1.9 1 1 0 1 1 1 0 SPX domain Bud13 PF09736.9 CDJ70478.1 - 3.7 7.9 7.5 5.8 7.3 7.5 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF4407 PF14362.6 CDJ70478.1 - 3.9 6.7 12.5 0.4 10.0 7.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) dsDNA_bind PF01984.20 CDJ70479.1 - 1.3e-20 73.7 12.3 1.6e-20 73.4 12.3 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4332 PF14229.6 CDJ70479.1 - 0.013 15.7 2.1 0.019 15.2 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4332) DUF4711 PF15829.5 CDJ70479.1 - 0.021 14.8 1.4 0.025 14.5 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) DUF4953 PF16313.5 CDJ70479.1 - 0.047 12.9 1.0 0.058 12.6 1.0 1.1 1 0 0 1 1 1 0 Met-zincin MAS20 PF02064.15 CDJ70479.1 - 4.1 7.5 9.0 2.2 8.4 7.1 1.5 1 1 0 1 1 1 0 MAS20 protein import receptor Mit_KHE1 PF10173.9 CDJ70480.1 - 0.065 13.3 2.4 0.072 13.2 2.4 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Phostensin_N PF13916.6 CDJ70480.1 - 1.7 9.0 11.2 4.6 7.7 2.0 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal SR-25 PF10500.9 CDJ70482.1 - 0.0013 18.4 9.9 0.0013 18.4 9.9 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ70483.1 - 0.019 14.6 11.6 0.029 14.0 11.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUZ PF12752.7 CDJ70483.1 - 0.025 15.3 2.0 0.025 15.3 2.0 1.8 2 0 0 2 2 2 0 SUZ domain PAP1 PF08601.10 CDJ70483.1 - 0.18 11.5 2.6 0.19 11.4 2.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF3774 PF12609.8 CDJ70483.1 - 0.28 12.2 5.5 0.22 12.6 1.6 2.2 2 0 0 2 2 2 0 Wound-induced protein DUF3446 PF11928.8 CDJ70483.1 - 0.87 9.9 22.3 0.059 13.7 9.5 2.2 1 1 1 2 2 2 0 Early growth response N-terminal domain Macoilin PF09726.9 CDJ70484.1 - 0.3 9.6 7.9 0.33 9.5 7.9 1.0 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CDJ70484.1 - 0.31 11.0 22.7 0.47 10.4 22.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 CDJ70484.1 - 1.8 7.7 6.4 2.2 7.4 6.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ70484.1 - 2.9 6.6 11.1 3.6 6.2 11.1 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 CDJ70484.1 - 3.9 7.0 11.0 4.5 6.7 11.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LMBR1 PF04791.16 CDJ70484.1 - 4.3 6.1 4.8 5 5.9 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2681 PF10883.8 CDJ70484.1 - 5.7 7.4 17.9 6.7 7.2 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TAF4 PF05236.14 CDJ70484.1 - 6.3 6.5 16.8 1.6 8.4 5.6 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Protamine_P2 PF00841.19 CDJ70484.1 - 7.7 7.1 15.6 2.5 8.6 8.6 2.2 2 0 0 2 2 2 0 Sperm histone P2 SLC12 PF03522.15 CDJ70484.1 - 7.9 5.4 9.1 9.4 5.1 9.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MutS_III PF05192.18 CDJ70485.1 - 1.1e-07 32.2 6.0 6.8e-07 29.7 6.0 2.2 1 1 0 1 1 1 1 MutS domain III Med3 PF11593.8 CDJ70485.1 - 0.36 10.0 11.9 0.71 9.0 11.9 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1499 PF07386.11 CDJ70485.1 - 2.6 8.6 4.9 3.7 8.1 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1499) AAA_2 PF07724.14 CDJ70486.1 - 3e-24 86.0 0.0 6.3e-23 81.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 CDJ70486.1 - 3.4e-15 55.9 0.0 6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CDJ70486.1 - 0.00096 19.2 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Ribosomal_60s PF00428.19 CDJ70486.1 - 5.9 7.6 15.8 4 8.1 12.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Histone_HNS PF00816.21 CDJ70487.1 - 0.13 13.1 1.0 1 10.2 0.2 2.7 3 0 0 3 3 3 0 H-NS histone family Tox-HNH-HHH PF15637.6 CDJ70487.1 - 0.22 11.7 0.0 1.2 9.3 0.0 2.0 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Zfx_Zfy_act PF04704.13 CDJ70488.1 - 2.2 7.3 6.1 2.3 7.3 6.1 1.1 1 0 0 1 1 1 0 Zfx / Zfy transcription activation region VPS9 PF02204.18 CDJ70489.1 - 3.5e-23 81.8 0.0 6.2e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain TFIIA PF03153.13 CDJ70490.1 - 0.011 15.8 45.8 0.014 15.4 45.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 CDJ70490.1 - 0.52 8.9 15.1 0.55 8.8 15.1 1.0 1 0 0 1 1 1 0 Hamartin protein SRP-alpha_N PF04086.13 CDJ70490.1 - 0.76 9.6 26.6 1 9.2 26.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC27 PF09507.10 CDJ70490.1 - 1.3 8.3 23.6 1.6 8.1 23.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAT1 PF09770.9 CDJ70490.1 - 2.1 6.5 33.4 2.4 6.3 33.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nucleo_P87 PF07267.11 CDJ70490.1 - 2.2 7.0 19.4 2.7 6.7 19.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PmbA_TldD PF01523.16 CDJ70490.1 - 2.3 8.0 9.6 3.5 7.4 9.6 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Glyco_transf_20 PF00982.21 CDJ70490.1 - 2.4 6.7 10.8 1.9 7.0 10.0 1.3 1 1 0 1 1 1 0 Glycosyltransferase family 20 SOBP PF15279.6 CDJ70490.1 - 3.8 8.1 17.5 4.8 7.7 17.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein IHABP4_N PF16174.5 CDJ70490.1 - 3.8 8.1 33.3 6.5 7.3 33.3 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal O-antigen_lig PF13425.6 CDJ70490.1 - 4.2 6.0 3.8 4.5 5.9 3.8 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein BAF1_ABF1 PF04684.13 CDJ70490.1 - 5.6 5.9 23.3 8 5.4 23.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF966 PF06136.13 CDJ70490.1 - 7.2 6.2 18.7 8.1 6.1 18.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Ndc1_Nup PF09531.10 CDJ70490.1 - 7.4 5.1 24.3 8.6 4.9 24.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ephrin_rec_like PF07699.13 CDJ70491.1 - 5.5e-08 32.4 179.1 2.9e-05 23.7 3.3 17.2 12 6 4 16 16 16 9 Putative ephrin-receptor like EPL1 PF10513.9 CDJ70491.1 - 0.00067 20.1 0.3 0.00067 20.1 0.3 4.4 4 0 0 4 4 4 2 Enhancer of polycomb-like Phage_portal PF04860.12 CDJ70491.1 - 0.025 13.8 5.4 0.068 12.4 5.4 1.7 1 0 0 1 1 1 0 Phage portal protein RskA PF10099.9 CDJ70491.1 - 3.9 7.7 120.5 0.068 13.5 26.7 8.0 7 1 1 8 8 8 0 Anti-sigma-K factor rskA zf-CCHC PF00098.23 CDJ70492.1 - 4.8e-05 23.2 10.1 0.0014 18.6 1.2 2.4 2 0 0 2 2 2 2 Zinc knuckle Retrotrans_gag PF03732.17 CDJ70492.1 - 0.0024 18.1 0.0 0.0048 17.1 0.0 1.5 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_6 PF15288.6 CDJ70492.1 - 0.17 11.7 0.5 0.17 11.7 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CDJ70492.1 - 0.5 10.8 8.9 1.6 9.2 8.9 1.8 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_3 PF13917.6 CDJ70492.1 - 2.2 8.3 6.9 0.7 9.9 0.7 2.5 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ70492.1 - 3.8 7.3 8.5 7.8 6.3 2.4 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 CDJ70492.1 - 4.3 7.1 5.7 13 5.6 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle FANC_SAP PF18081.1 CDJ70493.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.8 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain SKA1 PF07160.12 CDJ70494.1 - 0.0063 16.4 1.9 0.015 15.2 1.9 1.5 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 ApoLp-III PF07464.11 CDJ70495.1 - 3.9 7.6 7.9 0.83 9.7 0.2 3.2 4 1 1 5 5 5 0 Apolipophorin-III precursor (apoLp-III) Snapin_Pallidin PF14712.6 CDJ70495.1 - 3.9 7.9 7.1 21 5.6 1.9 3.0 2 0 0 2 2 2 0 Snapin/Pallidin Cnn_1N PF07989.11 CDJ70495.1 - 5 7.3 6.1 86 3.4 3.3 3.1 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 FliJ PF02050.16 CDJ70495.1 - 7 6.9 8.7 0.94 9.7 2.7 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein MFS_1 PF07690.16 CDJ70496.1 - 9.3e-22 77.4 17.1 1.3e-21 76.9 17.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Apt1 PF10351.9 CDJ70496.1 - 3.4 6.4 6.9 4.9 5.9 6.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ70496.1 - 8.1 4.9 8.0 12 4.3 8.0 1.1 1 0 0 1 1 1 0 Macoilin family PolyA_pol PF01743.20 CDJ70498.1 - 1e-22 80.9 0.3 6e-22 78.4 0.0 2.5 4 0 0 4 4 4 1 Poly A polymerase head domain SAB PF04382.13 CDJ70499.1 - 0.15 12.1 0.5 0.38 10.9 0.5 1.7 1 0 0 1 1 1 0 SAB domain Mito_carr PF00153.27 CDJ70502.1 - 1.6e-23 82.5 0.2 1.9e-12 46.9 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein NIF PF03031.18 CDJ70503.1 - 1.8e-47 161.0 0.2 2.4e-47 160.6 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Vta1 PF04652.16 CDJ70504.1 - 0.11 12.5 0.5 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 Vta1 like PAT1 PF09770.9 CDJ70505.1 - 1.6 6.9 54.8 1.9 6.7 54.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tim54 PF11711.8 CDJ70506.1 - 0.00048 19.0 0.5 0.0006 18.7 0.5 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.13 CDJ70506.1 - 0.014 15.4 21.5 0.017 15.2 21.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BSMAP PF12280.8 CDJ70506.1 - 0.017 15.3 1.0 0.017 15.3 1.0 1.8 1 1 1 2 2 2 0 Brain specific membrane anchored protein PA26 PF04636.13 CDJ70506.1 - 0.052 12.5 1.2 0.066 12.1 1.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Zip PF02535.22 CDJ70506.1 - 0.062 12.5 0.1 0.072 12.3 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 CDJ70506.1 - 0.072 13.1 2.0 0.095 12.7 2.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hydin_ADK PF17213.3 CDJ70506.1 - 0.088 13.1 6.1 0.11 12.7 6.1 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SARAF PF06682.12 CDJ70506.1 - 0.17 11.5 5.8 0.22 11.1 5.8 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis GREB1 PF15782.5 CDJ70506.1 - 0.21 8.7 4.7 0.23 8.5 4.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Suf PF05843.14 CDJ70506.1 - 0.22 11.5 12.0 0.26 11.2 12.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ATF7IP_BD PF16788.5 CDJ70506.1 - 0.68 10.0 7.4 0.15 12.2 3.3 1.7 1 1 1 2 2 2 0 ATF-interacting protein binding domain Presenilin PF01080.17 CDJ70506.1 - 0.99 8.1 5.7 1.3 7.7 5.7 1.1 1 0 0 1 1 1 0 Presenilin HemX PF04375.14 CDJ70506.1 - 1.4 8.2 13.9 0.049 12.9 8.2 1.5 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spt20 PF12090.8 CDJ70508.1 - 0.00032 20.4 10.9 0.00044 19.9 10.9 1.3 1 0 0 1 1 1 1 Spt20 family RIFIN PF02009.16 CDJ70508.1 - 0.057 13.3 5.2 0.075 12.9 5.2 1.2 1 0 0 1 1 1 0 Rifin DC_STAMP PF07782.13 CDJ70508.1 - 0.13 12.1 0.6 0.2 11.5 0.6 1.3 1 0 0 1 1 1 0 DC-STAMP-like protein TFIIA PF03153.13 CDJ70508.1 - 0.46 10.4 14.1 0.52 10.3 14.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5383 PF17355.2 CDJ70508.1 - 0.66 10.3 6.5 0.17 12.2 2.1 2.1 1 1 2 3 3 3 0 Family of unknown function (DUF5383) Mcm10 PF09332.11 CDJ70508.1 - 0.96 8.8 16.1 1.2 8.5 16.1 1.1 1 0 0 1 1 1 0 Mcm10 replication factor RabGAP-TBC PF00566.18 CDJ70509.1 - 1.5e-27 96.7 0.1 1.5e-27 96.7 0.1 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Apt1 PF10351.9 CDJ70509.1 - 2.3 7.0 3.8 4.3 6.1 3.8 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ephrin_rec_like PF07699.13 CDJ70511.1 - 2.5e-05 23.9 4.4 2.5e-05 23.9 4.4 4.0 2 2 1 3 3 3 2 Putative ephrin-receptor like PsbQ PF05757.11 CDJ70511.1 - 3.4 7.4 9.4 8.4 6.1 9.4 1.7 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) M_domain PF12938.7 CDJ70513.1 - 0.13 12.0 26.5 0.14 11.9 10.2 2.9 3 0 0 3 3 3 0 M domain of GW182 SUIM_assoc PF16619.5 CDJ70513.1 - 1.1 9.3 29.7 1.3 9.2 10.8 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 YajC PF02699.15 CDJ70513.1 - 6.8 6.7 19.8 2.4 8.1 7.0 2.5 2 0 0 2 2 2 0 Preprotein translocase subunit Ribosomal_60s PF00428.19 CDJ70514.1 - 0.00058 20.4 3.7 0.00089 19.8 3.7 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Presenilin PF01080.17 CDJ70516.1 - 3.2e-07 29.5 12.9 4.7e-07 28.9 12.9 1.2 1 0 0 1 1 1 1 Presenilin SARAF PF06682.12 CDJ70516.1 - 0.014 15.1 0.0 0.014 15.1 0.0 2.5 1 1 1 2 2 1 0 SOCE-associated regulatory factor of calcium homoeostasis LAP1C PF05609.12 CDJ70516.1 - 0.077 12.1 20.1 0.099 11.7 20.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SR-25 PF10500.9 CDJ70516.1 - 0.098 12.3 24.9 0.16 11.6 24.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TAF1D PF15333.6 CDJ70516.1 - 0.45 10.2 19.7 0.68 9.6 19.7 1.3 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF4131 PF13567.6 CDJ70516.1 - 0.6 9.7 11.0 0.042 13.5 2.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) IMUP PF15761.5 CDJ70516.1 - 1.2 9.9 18.1 2.6 8.8 17.1 2.1 1 1 0 1 1 1 0 Immortalisation up-regulated protein DUF966 PF06136.13 CDJ70516.1 - 1.5 8.5 23.5 1.9 8.1 23.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) GREB1 PF15782.5 CDJ70516.1 - 1.5 5.8 21.4 1.9 5.5 21.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 CDJ70516.1 - 1.5 7.0 17.5 2.1 6.5 17.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3742 PF12553.8 CDJ70516.1 - 4.7 7.4 6.7 0.37 10.9 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3742) SRP-alpha_N PF04086.13 CDJ70516.1 - 4.8 7.0 25.7 7.3 6.4 25.7 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Borrelia_P83 PF05262.11 CDJ70516.1 - 8.8 4.7 27.3 11 4.4 27.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Vac7 PF12751.7 CDJ70516.1 - 9.7 5.5 23.6 17 4.7 23.6 1.4 1 1 0 1 1 1 0 Vacuolar segregation subunit 7 Myc_N PF01056.18 CDJ70517.1 - 0.0066 16.4 0.2 0.0066 16.4 0.2 3.9 2 1 2 4 4 4 1 Myc amino-terminal region SUIM_assoc PF16619.5 CDJ70517.1 - 0.014 15.4 8.0 0.014 15.4 8.0 7.6 4 2 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 zf-rbx1 PF12678.7 CDJ70517.1 - 0.033 14.5 6.1 0.7 10.2 0.2 3.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CDJ70517.1 - 0.2 11.5 1.0 5 7.1 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ70517.1 - 0.91 9.9 3.2 1.9 8.9 0.2 2.3 2 0 0 2 2 2 0 Ring finger domain RNA_pol_L_2 PF13656.6 CDJ70518.1 - 2.6e-08 33.5 0.1 5.6e-06 26.0 0.0 2.2 1 1 1 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain UBN_AB PF14075.6 CDJ70518.1 - 0.00052 19.8 0.9 0.00063 19.5 0.9 1.1 1 0 0 1 1 1 1 Ubinuclein conserved middle domain RAP1 PF07218.11 CDJ70518.1 - 0.00065 18.1 1.9 0.00081 17.8 1.9 1.0 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) RNA_pol_L PF01193.24 CDJ70518.1 - 0.027 13.9 0.1 0.16 11.4 0.1 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Presenilin PF01080.17 CDJ70518.1 - 0.28 9.9 5.7 0.33 9.7 5.7 1.1 1 0 0 1 1 1 0 Presenilin Miga PF10265.9 CDJ70518.1 - 0.88 8.5 8.5 0.97 8.3 8.5 1.0 1 0 0 1 1 1 0 Mitoguardin ANAPC_CDC26 PF10471.9 CDJ70518.1 - 2.9 8.8 19.3 0.59 11.0 12.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 MscS_TM PF12794.7 CDJ70518.1 - 7.6 5.3 7.0 11 4.7 7.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SUZ PF12752.7 CDJ70518.1 - 9.5 7.1 10.3 1.3 9.8 4.1 2.3 2 0 0 2 2 2 0 SUZ domain Het-C PF07217.11 CDJ70519.1 - 1.9 6.9 9.1 2.3 6.6 9.1 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Imm49 PF15575.6 CDJ70519.1 - 2.1 8.1 8.6 0.58 9.9 5.7 1.6 2 0 0 2 2 2 0 Immunity protein 49 Sec63 PF02889.16 CDJ70521.1 - 0.039 13.1 0.0 0.11 11.7 0.0 1.7 1 1 0 1 1 1 0 Sec63 Brl domain DUF1180 PF06679.12 CDJ70522.1 - 0.081 13.3 8.5 0.13 12.7 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Med15 PF09606.10 CDJ70523.1 - 0.0014 17.4 14.6 0.0014 17.4 14.6 2.2 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CDJ70523.1 - 0.0015 17.5 21.1 0.0021 17.1 7.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ70523.1 - 0.3 11.4 11.1 0.63 10.4 2.5 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like EOS1 PF12326.8 CDJ70523.1 - 0.31 10.9 0.9 7.3 6.5 0.0 2.2 2 0 0 2 2 2 0 N-glycosylation protein DUF1387 PF07139.11 CDJ70523.1 - 0.33 10.6 15.3 1.7 8.3 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Pex14_N PF04695.13 CDJ70523.1 - 0.77 10.4 33.5 0.27 11.9 5.8 4.1 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ATAD4 PF15321.6 CDJ70523.1 - 3.1 9.2 10.6 18 6.7 1.1 2.6 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Neur_chan_memb PF02932.16 CDJ70523.1 - 3.2 7.8 14.0 5.5 7.0 2.5 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 CDJ70523.1 - 3.3 7.4 5.5 3.3 7.4 0.6 2.3 2 0 0 2 2 2 0 Connexin FAM60A PF15396.6 CDJ70523.1 - 3.7 7.5 9.4 8 6.4 1.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Ctr PF04145.15 CDJ70523.1 - 7 7.3 11.9 6.9 7.3 1.7 2.8 3 0 0 3 3 3 0 Ctr copper transporter family Exonuc_VII_L PF02601.15 CDJ70524.1 - 0.0092 15.6 12.2 0.013 15.1 12.2 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit IFT57 PF10498.9 CDJ70524.1 - 0.011 14.8 4.2 0.018 14.0 4.2 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 CDJ70524.1 - 0.047 12.6 11.8 0.084 11.7 11.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein BRCA-2_OB3 PF09104.10 CDJ70524.1 - 0.086 12.5 0.7 0.15 11.7 0.7 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Retrotrans_gag PF03732.17 CDJ70524.1 - 0.42 10.9 4.0 0.22 11.8 1.3 1.9 1 1 1 2 2 2 0 Retrotransposon gag protein Striatin PF08232.12 CDJ70524.1 - 1.4 9.5 16.2 0.21 12.2 7.2 2.2 2 0 0 2 2 2 0 Striatin family RNA_pol_Rpc4 PF05132.14 CDJ70524.1 - 2.6 8.5 12.1 3 8.2 1.5 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 IFT57 PF10498.9 CDJ70525.1 - 0.01 14.8 0.0 0.013 14.5 0.0 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 WD40 PF00400.32 CDJ70527.1 - 2.9e-09 37.4 10.3 0.73 10.8 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ70527.1 - 0.00025 21.3 0.0 0.45 10.8 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ion_trans PF00520.31 CDJ70529.1 - 2.9e-46 157.7 75.8 1.4e-16 60.5 17.7 4.3 4 0 0 4 4 4 4 Ion transport protein Kinesin PF00225.23 CDJ70530.1 - 3.3e-88 295.8 4.0 1.2e-43 149.3 0.0 2.9 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ70530.1 - 1.3e-21 77.1 0.4 1.2e-20 74.0 0.4 2.6 1 1 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 CDJ70530.1 - 2.2e-06 28.0 0.6 6.8e-05 23.2 0.0 3.3 2 0 0 2 2 2 1 Kinesin protein 1B Kinesin_assoc PF16183.5 CDJ70530.1 - 0.0013 18.9 0.5 0.0013 18.9 0.5 4.0 3 1 1 4 4 4 2 Kinesin-associated FHA PF00498.26 CDJ70530.1 - 0.006 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain DinB PF05163.12 CDJ70530.1 - 7.8 6.4 15.2 0.87 9.5 0.3 3.0 2 1 0 2 2 2 0 DinB family zf-CCHC PF00098.23 CDJ70531.1 - 0.002 18.1 1.2 0.002 18.1 1.2 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ70531.1 - 0.018 15.0 0.1 0.052 13.5 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 CDJ70531.1 - 0.044 13.6 2.0 0.084 12.7 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 CDJ70531.1 - 0.17 12.2 0.8 0.36 11.1 0.4 1.7 1 1 1 2 2 2 0 Retrotransposon gag protein zf-ribbon_3 PF13248.6 CDJ70531.1 - 0.23 10.9 0.8 0.42 10.1 0.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain RT_RNaseH PF17917.1 CDJ70532.1 - 8.1e-28 96.8 0.0 1.2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ70532.1 - 3.3e-26 91.2 0.0 6.6e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ70532.1 - 0.00041 20.1 0.0 0.00065 19.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like rve PF00665.26 CDJ70533.1 - 9.9e-12 45.1 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ70533.1 - 0.022 14.5 1.6 0.091 12.6 0.1 2.6 3 0 0 3 3 3 0 Integrase core domain GLTSCR1 PF15249.6 CDJ70533.1 - 0.089 13.2 0.2 2.6 8.5 0.1 2.3 1 1 1 2 2 2 0 Conserved region of unknown function on GLTSCR protein RVT_1 PF00078.27 CDJ70534.1 - 2.6e-23 82.7 0.0 4.9e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CDJ70534.1 - 4.1e-06 27.4 0.4 1.6e-05 25.5 0.0 2.2 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase DUF3824 PF12868.7 CDJ70535.1 - 0.0027 18.4 10.0 0.0036 18.0 10.0 1.1 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) DUF5427 PF10310.9 CDJ70535.1 - 0.025 13.5 19.9 0.032 13.2 19.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SMYLE_N PF18615.1 CDJ70535.1 - 0.051 13.1 10.8 0.056 13.0 10.8 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF966 PF06136.13 CDJ70535.1 - 0.073 12.8 10.6 0.079 12.7 10.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Suf PF05843.14 CDJ70535.1 - 0.073 13.0 21.1 0.081 12.9 21.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ70535.1 - 0.088 12.8 45.2 0.14 12.2 45.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 CDJ70535.1 - 0.15 12.0 16.6 0.22 11.5 16.6 1.3 1 0 0 1 1 1 0 Velvet factor SLC12 PF03522.15 CDJ70535.1 - 0.16 11.0 18.2 0.17 10.9 18.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PAT1 PF09770.9 CDJ70535.1 - 0.21 9.8 33.4 0.24 9.7 33.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4569 PF15133.6 CDJ70535.1 - 0.23 11.2 18.8 0.33 10.6 18.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Y_phosphatase3 PF13350.6 CDJ70535.1 - 0.24 11.3 0.1 0.24 11.3 0.1 2.1 1 1 1 2 2 2 0 Tyrosine phosphatase family CDC45 PF02724.14 CDJ70535.1 - 0.3 9.3 14.6 0.33 9.2 14.6 1.0 1 0 0 1 1 1 0 CDC45-like protein MAT1 PF06391.13 CDJ70535.1 - 0.33 10.8 26.9 0.4 10.5 26.9 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Presenilin PF01080.17 CDJ70535.1 - 0.36 9.6 23.9 0.43 9.3 23.9 1.0 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 CDJ70535.1 - 0.47 10.0 21.9 0.55 9.7 21.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hydin_ADK PF17213.3 CDJ70535.1 - 0.61 10.3 14.2 0.76 10.0 14.2 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Dicty_REP PF05086.12 CDJ70535.1 - 0.77 7.7 10.3 0.87 7.5 10.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein V_ATPase_I PF01496.19 CDJ70535.1 - 1.2 7.0 15.9 1.4 6.8 15.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Senescence_reg PF04520.13 CDJ70535.1 - 1.4 9.8 13.3 2 9.2 13.3 1.3 1 0 0 1 1 1 0 Senescence regulator Sec62 PF03839.16 CDJ70535.1 - 1.7 8.1 19.0 2.1 7.8 19.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 LAP1C PF05609.12 CDJ70535.1 - 1.8 7.6 20.1 2.1 7.4 20.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Med15 PF09606.10 CDJ70535.1 - 2 7.0 49.6 2.3 6.8 49.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.12 CDJ70535.1 - 2 8.2 21.4 2.6 7.8 21.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CDJ70535.1 - 2.1 5.4 17.1 2.1 5.4 17.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 CDJ70535.1 - 2.6 8.1 15.7 3.1 7.8 15.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 CDJ70535.1 - 3 7.8 15.2 3.9 7.4 15.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 CDJ70535.1 - 4.6 5.3 19.6 5.1 5.1 19.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Exonuc_VII_L PF02601.15 CDJ70535.1 - 5.3 6.5 19.1 6.1 6.3 19.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MAJIN PF15077.6 CDJ70535.1 - 5.8 6.6 13.6 6.7 6.4 13.6 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF2052 PF09747.9 CDJ70535.1 - 6.3 6.9 23.5 8.1 6.5 23.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) ALMT PF11744.8 CDJ70535.1 - 7.9 5.2 16.3 9.3 5.0 16.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 CDJ70535.1 - 7.9 5.6 12.8 9.9 5.3 12.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter WTX PF09422.10 CDJ70535.1 - 8.1 5.4 16.4 9.5 5.2 16.4 1.0 1 0 0 1 1 1 0 WTX protein Membralin PF09746.9 CDJ70535.1 - 8.2 5.3 11.1 9.8 5.1 11.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein SR-25 PF10500.9 CDJ70536.1 - 0.013 15.2 6.4 0.015 14.9 6.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF515 PF04415.12 CDJ70536.1 - 0.37 9.1 3.6 0.41 9.0 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF3446 PF11928.8 CDJ70536.1 - 1.3 9.4 11.3 1.8 8.9 11.3 1.3 1 1 0 1 1 1 0 Early growth response N-terminal domain SPX PF03105.19 CDJ70537.1 - 0.00084 19.4 19.2 0.0065 16.4 1.9 2.6 2 1 0 2 2 2 2 SPX domain RskA PF10099.9 CDJ70537.1 - 0.11 12.8 73.6 0.19 12.0 9.5 4.9 4 1 1 5 5 5 0 Anti-sigma-K factor rskA YfhO PF09586.10 CDJ70537.1 - 0.7 8.1 7.6 0.26 9.5 0.7 2.0 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF4131 PF13567.6 CDJ70537.1 - 0.77 9.4 8.8 0.045 13.4 2.4 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) SKA1 PF07160.12 CDJ70537.1 - 1.4 8.7 10.5 0.86 9.4 1.3 3.4 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 LRR19-TM PF15176.6 CDJ70537.1 - 2.8 8.0 5.2 0.4 10.7 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain V_ATPase_I PF01496.19 CDJ70537.1 - 5.9 4.7 5.7 10 3.9 2.2 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4821 PF16092.5 CDJ70538.1 - 1.1e-17 64.5 2.6 3.3e-15 56.4 0.2 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4821) YdjM PF04307.14 CDJ70538.1 - 0.0028 17.0 1.9 0.0028 17.0 1.9 3.0 3 1 0 3 3 3 1 LexA-binding, inner membrane-associated putative hydrolase Apt1 PF10351.9 CDJ70538.1 - 0.0098 14.8 27.6 0.03 13.2 9.4 2.1 2 0 0 2 2 2 2 Golgi-body localisation protein domain Transposase_24 PF03004.14 CDJ70538.1 - 0.021 14.9 2.1 0.021 14.9 2.1 3.4 2 1 0 3 3 3 0 Plant transposase (Ptta/En/Spm family) NPR3 PF03666.13 CDJ70538.1 - 5.1 5.8 17.1 0.047 12.5 1.6 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_pol_Rpc4 PF05132.14 CDJ70538.1 - 7.1 7.1 16.6 7.2 7.0 0.0 4.0 3 1 0 3 3 3 0 RNA polymerase III RPC4 RNA_pol_I_TF PF04090.12 CDJ70539.1 - 0.18 11.3 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor DUF2057 PF09829.9 CDJ70540.1 - 0.42 10.7 14.8 0.049 13.8 9.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) DDE_Tnp_IS66 PF03050.14 CDJ70540.1 - 0.83 9.1 7.0 2 7.8 7.0 1.6 1 0 0 1 1 1 0 Transposase IS66 family Presenilin PF01080.17 CDJ70540.1 - 2.2 6.9 4.2 3.8 6.2 1.1 2.2 2 0 0 2 2 2 0 Presenilin DUF3138 PF11336.8 CDJ70540.1 - 5.2 5.6 9.4 9.9 4.6 9.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) V_ATPase_I PF01496.19 CDJ70540.1 - 7.8 4.3 9.2 0.56 8.1 3.7 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TGT PF01702.18 CDJ70541.1 - 2.2e-34 119.2 12.1 9.5e-26 90.8 0.1 2.2 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase O-antigen_lig PF13425.6 CDJ70542.1 - 0.0026 16.6 3.1 0.0027 16.6 3.1 1.0 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Jnk-SapK_ap_N PF09744.9 CDJ70542.1 - 0.0028 17.9 12.6 0.0033 17.7 12.6 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 ALMS_motif PF15309.6 CDJ70542.1 - 0.018 15.5 18.7 0.018 15.5 18.7 1.4 2 0 0 2 2 2 0 ALMS motif TMEM51 PF15345.6 CDJ70542.1 - 0.03 14.2 5.2 0.037 13.9 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 HSP70 PF00012.20 CDJ70542.1 - 1.1 7.4 13.4 1.3 7.1 13.4 1.1 1 0 0 1 1 1 0 Hsp70 protein GAGA_bind PF06217.12 CDJ70542.1 - 1.6 8.9 11.9 2 8.7 11.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.16 CDJ70542.1 - 4.6 7.2 7.0 5.5 7.0 7.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Borrelia_P83 PF05262.11 CDJ70542.1 - 4.9 5.5 20.2 6.3 5.2 20.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 CDJ70542.1 - 6.6 6.5 15.9 8.4 6.1 15.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 CDJ70542.1 - 9.9 5.4 13.3 13 5.0 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TTL PF03133.15 CDJ70543.1 - 8.9e-27 94.0 9.9 2.7e-16 59.6 0.0 4.7 4 1 0 4 4 4 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CDJ70543.1 - 9.4e-06 25.1 0.0 9.4e-06 25.1 0.0 4.5 4 2 1 5 5 5 2 YheC/D like ATP-grasp RimK PF08443.11 CDJ70543.1 - 0.00095 18.8 0.0 0.96 9.0 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain RNase_H2_suC PF08615.11 CDJ70543.1 - 0.0088 16.2 0.4 0.0088 16.2 0.4 4.6 2 1 0 3 3 3 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SUIM_assoc PF16619.5 CDJ70543.1 - 0.02 14.9 0.3 0.02 14.9 0.3 15.0 10 4 2 12 12 12 0 Unstructured region C-term to UIM in Ataxin3 ATPgrasp_ST PF14397.6 CDJ70543.1 - 0.027 13.7 0.0 0.075 12.3 0.0 1.7 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp zf-RING_2 PF13639.6 CDJ70544.1 - 3.1e-12 46.6 4.4 4.7e-12 46.0 4.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CDJ70544.1 - 1.7e-09 37.8 7.5 1.6e-08 34.7 7.5 2.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDJ70544.1 - 1.7e-08 34.2 4.0 3.3e-08 33.2 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ70544.1 - 5.9e-07 29.1 2.5 1.2e-06 28.2 2.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDJ70544.1 - 1.4e-06 28.0 3.9 2.6e-06 27.2 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ70544.1 - 2.3e-06 27.5 3.7 8.9e-06 25.6 3.7 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ70544.1 - 9.6e-06 25.5 3.0 2.4e-05 24.2 3.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CDJ70544.1 - 1.1e-05 25.3 0.8 4.8e-05 23.3 0.8 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CDJ70544.1 - 1.3e-05 25.3 2.6 3.3e-05 24.0 2.6 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 CDJ70544.1 - 0.0054 16.6 2.3 0.0096 15.8 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CDJ70544.1 - 0.018 14.7 2.7 0.034 13.8 2.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CPSF100_C PF13299.6 CDJ70544.1 - 0.022 14.9 2.5 0.022 14.9 2.5 4.2 2 1 1 3 3 1 0 Cleavage and polyadenylation factor 2 C-terminal Rad50_zn_hook PF04423.14 CDJ70544.1 - 0.036 13.9 0.2 0.074 12.9 0.2 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif PHD PF00628.29 CDJ70544.1 - 0.061 13.2 3.1 0.16 11.9 3.1 1.8 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 CDJ70544.1 - 0.08 12.8 1.1 0.16 11.8 1.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 CDJ70544.1 - 0.083 13.0 4.1 0.17 12.0 4.1 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 CDJ70544.1 - 0.22 11.3 2.6 0.41 10.5 2.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 CDJ70544.1 - 0.29 11.1 2.1 4.4 7.3 0.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CCSAP PF15748.5 CDJ70544.1 - 1 9.4 59.7 0.9 9.7 10.3 3.1 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated Prok-RING_4 PF14447.6 CDJ70544.1 - 1.8 8.5 5.0 6.6 6.7 5.0 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 MecA PF05389.12 CDJ70544.1 - 2.5 7.7 23.8 0.2 11.3 3.6 3.2 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) zf-P11 PF03854.14 CDJ70544.1 - 4.8 6.9 5.4 0.56 9.9 1.1 1.6 2 0 0 2 2 1 0 P-11 zinc finger NICE-1 PF15845.5 CDJ70545.1 - 0.00013 22.6 14.6 0.00013 22.6 14.6 2.9 2 1 0 2 2 2 1 Cysteine-rich C-terminal 1 family EPL1 PF10513.9 CDJ70545.1 - 0.21 11.9 6.6 2.9 8.3 0.2 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Pro_isomerase PF00160.21 CDJ70547.1 - 2.1e-12 47.6 1.2 2.8e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CDJ70547.1 - 2.1e-11 43.5 0.1 1.5e-08 34.3 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.19 CDJ70547.1 - 0.0083 16.7 13.6 0.0083 16.7 13.6 4.3 4 1 1 5 5 5 2 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ70547.1 - 0.26 10.8 0.0 0.26 10.8 0.0 3.3 3 0 0 3 3 3 0 Spt20 family FdhD-NarQ PF02634.15 CDJ70547.1 - 0.9 9.2 8.4 7 6.2 4.6 2.4 2 0 0 2 2 2 0 FdhD/NarQ family YafO_toxin PF13957.6 CDJ70548.1 - 0.018 15.1 1.4 0.028 14.5 1.4 1.4 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system DUF4710 PF15828.5 CDJ70548.1 - 0.036 14.2 0.6 0.036 14.2 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) SUIM_assoc PF16619.5 CDJ70548.1 - 0.039 14.0 3.4 0.039 14.0 3.4 3.3 3 2 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ70548.1 - 0.16 11.9 26.2 0.18 11.8 26.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 CDJ70548.1 - 0.2 9.9 4.8 0.19 10.0 4.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PH_BEACH PF14844.6 CDJ70548.1 - 0.78 9.9 3.9 1.5 9.0 0.0 2.2 1 1 1 2 2 2 0 PH domain associated with Beige/BEACH Tir_receptor_N PF07490.11 CDJ70548.1 - 2.7 7.7 10.0 5.1 6.9 5.1 2.1 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus DUF508 PF04370.12 CDJ70548.1 - 3.5 7.4 14.0 6.1 6.6 14.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Serinc PF03348.15 CDJ70548.1 - 7.4 5.4 6.9 8.7 5.2 6.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.13 CDJ70549.1 - 3 7.7 6.7 3.8 7.4 6.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C54 PF03416.19 CDJ70550.1 - 6.2e-12 45.5 0.2 6.2e-12 45.5 0.2 3.1 3 0 0 3 3 3 1 Peptidase family C54 Ribosomal_S9 PF00380.19 CDJ70551.1 - 5.8e-27 94.6 0.1 5.8e-27 94.6 0.1 2.1 3 0 0 3 3 3 1 Ribosomal protein S9/S16 tRNA_int_endo_N PF02778.14 CDJ70551.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain FAM176 PF14851.6 CDJ70552.1 - 0.0013 18.4 7.0 0.017 14.8 0.2 2.4 2 0 0 2 2 2 1 FAM176 family OATP PF03137.20 CDJ70552.1 - 0.0031 15.9 2.6 0.039 12.2 0.2 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Connexin PF00029.19 CDJ70552.1 - 0.01 15.6 4.7 0.086 12.6 0.2 2.1 2 0 0 2 2 2 0 Connexin SARAF PF06682.12 CDJ70552.1 - 0.013 15.2 13.1 0.075 12.7 4.8 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Serinc PF03348.15 CDJ70552.1 - 0.016 14.2 1.4 0.15 10.9 0.1 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) Presenilin PF01080.17 CDJ70552.1 - 0.034 12.9 11.5 0.58 8.9 5.6 2.1 2 0 0 2 2 2 0 Presenilin V_ATPase_I PF01496.19 CDJ70552.1 - 0.036 12.0 12.5 0.026 12.5 4.7 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family EMC3_TMCO1 PF01956.16 CDJ70552.1 - 0.039 13.7 0.3 0.039 13.7 0.3 2.6 3 0 0 3 3 2 0 Integral membrane protein EMC3/TMCO1-like CPSF100_C PF13299.6 CDJ70552.1 - 0.045 13.9 4.7 1.5 9.0 0.5 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EOS1 PF12326.8 CDJ70552.1 - 0.049 13.6 0.1 9.4 6.1 0.0 2.3 2 0 0 2 2 2 0 N-glycosylation protein CLN3 PF02487.17 CDJ70552.1 - 0.064 12.3 5.7 0.12 11.4 0.3 2.2 2 0 0 2 2 2 0 CLN3 protein SpoIIP PF07454.11 CDJ70552.1 - 0.12 11.8 11.0 0.085 12.3 0.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SID-1_RNA_chan PF13965.6 CDJ70552.1 - 0.12 10.8 0.3 0.67 8.3 0.1 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 O-antigen_lig PF13425.6 CDJ70552.1 - 0.14 11.0 1.1 1.2 7.8 0.0 2.0 2 0 0 2 2 2 0 O-antigen ligase like membrane protein BORG_CEP PF14957.6 CDJ70552.1 - 0.16 13.1 3.9 2 9.6 0.0 2.3 2 0 0 2 2 2 0 Cdc42 effector Ctr PF04145.15 CDJ70552.1 - 0.17 12.5 6.6 0.37 11.4 1.3 2.4 2 0 0 2 2 2 0 Ctr copper transporter family CCDC53 PF10152.9 CDJ70552.1 - 0.2 12.0 18.4 0.099 13.1 4.3 2.7 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex DUF2464 PF10240.9 CDJ70552.1 - 0.32 10.5 5.9 0.4 10.2 0.2 2.1 2 0 0 2 2 2 0 Multivesicular body subunit 12 DUF4820 PF16091.5 CDJ70552.1 - 0.39 10.0 12.1 0.27 10.6 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) PIP5K PF01504.18 CDJ70552.1 - 0.59 9.3 8.6 1.8 7.7 3.4 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase FAM163 PF15069.6 CDJ70552.1 - 1.1 9.6 11.6 0.054 13.9 4.5 2.1 2 0 0 2 2 2 0 FAM163 family Neur_chan_memb PF02932.16 CDJ70552.1 - 1.7 8.6 12.0 4.7 7.2 5.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1980 PF09323.10 CDJ70552.1 - 1.9 8.3 8.3 3.4 7.5 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) TFIIA PF03153.13 CDJ70552.1 - 2.6 8.0 58.8 0.064 13.3 16.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FHIPEP PF00771.20 CDJ70552.1 - 3.3 6.1 7.2 3.3 6.1 0.7 2.3 2 0 0 2 2 2 0 FHIPEP family Gti1_Pac2 PF09729.9 CDJ70552.1 - 7.4 6.6 11.3 18 5.4 5.1 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family SRPRB PF09439.10 CDJ70553.1 - 7.4e-14 51.6 0.0 8.3e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CDJ70553.1 - 4.7e-07 29.4 0.0 5.2e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ70553.1 - 0.00014 21.5 0.0 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ70553.1 - 0.018 15.1 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ70553.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF1467 PF07330.12 CDJ70555.1 - 0.91 9.5 6.5 2.9 7.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) DUF5523 PF17661.1 CDJ70555.1 - 4.2 7.0 12.0 1.9 8.1 5.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DUF572 PF04502.13 CDJ70555.1 - 7.2 6.1 20.6 9.9 5.7 20.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Tn7_Tnp_TnsA_C PF08721.11 CDJ70556.1 - 0.93 10.2 3.5 4.2 8.1 0.9 2.5 2 0 0 2 2 2 0 TnsA endonuclease C terminal EIF4E-T PF10477.9 CDJ70556.1 - 4.9 5.9 33.3 0.79 8.5 13.5 2.4 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E CRAL_TRIO PF00650.20 CDJ70557.1 - 1e-08 35.1 0.0 2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain AP2 PF00847.20 CDJ70558.1 - 3.7e-12 46.3 0.0 3.7e-12 46.3 0.0 4.5 6 0 0 6 6 6 1 AP2 domain CDC50 PF03381.15 CDJ70559.1 - 5e-28 98.4 1.6 1.8e-27 96.6 0.0 2.5 2 1 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RecO_C PF02565.15 CDJ70559.1 - 0.0056 16.5 2.7 0.59 9.9 0.4 2.9 2 0 0 2 2 2 2 Recombination protein O C terminal Acatn PF13000.7 CDJ70560.1 - 4.4e-19 68.4 0.0 2.2e-18 66.1 0.0 1.8 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 SR-25 PF10500.9 CDJ70560.1 - 0.3 10.7 9.9 0.38 10.3 9.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1712 PF08217.11 CDJ70561.1 - 2.7e-15 55.9 0.0 4.7e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) RskA PF10099.9 CDJ70561.1 - 0.014 15.7 9.6 0.014 15.7 9.6 2.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ70561.1 - 1.8 9.1 3.6 36 4.9 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) CDC45 PF02724.14 CDJ70562.1 - 0.00012 20.5 14.3 0.00013 20.4 14.3 1.2 1 0 0 1 1 1 1 CDC45-like protein SID-1_RNA_chan PF13965.6 CDJ70562.1 - 0.03 12.7 6.4 0.032 12.7 6.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Velvet PF11754.8 CDJ70562.1 - 0.045 13.7 18.1 0.061 13.3 18.1 1.4 1 0 0 1 1 1 0 Velvet factor CCSAP PF15748.5 CDJ70562.1 - 0.26 11.4 27.6 0.33 11.1 27.6 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated GAGA_bind PF06217.12 CDJ70562.1 - 0.5 10.6 19.9 0.6 10.4 19.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 CDJ70562.1 - 0.69 9.7 24.4 0.93 9.3 24.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 CDJ70562.1 - 0.76 8.0 43.7 0.88 7.8 43.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 CDJ70562.1 - 0.95 8.4 28.2 1.1 8.2 28.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ70562.1 - 0.97 8.1 32.8 1.3 7.8 32.8 1.1 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 CDJ70562.1 - 0.98 8.3 20.1 1.3 7.9 20.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MDM10 PF12519.8 CDJ70562.1 - 1 8.1 21.4 1.4 7.7 21.4 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Draxin PF15550.6 CDJ70562.1 - 1.6 8.5 19.2 2.1 8.1 19.2 1.2 1 0 0 1 1 1 0 Draxin Exonuc_VII_L PF02601.15 CDJ70562.1 - 1.7 8.1 35.4 2.4 7.6 35.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.8 CDJ70562.1 - 2 7.2 22.1 2.6 6.8 22.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 CDJ70562.1 - 2.1 8.4 19.2 2.8 7.9 19.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MRP-S26 PF14943.6 CDJ70562.1 - 2.2 8.2 32.7 4.3 7.2 32.7 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF572 PF04502.13 CDJ70562.1 - 2.2 7.8 23.5 2.8 7.5 23.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RIFIN PF02009.16 CDJ70562.1 - 3.8 7.3 21.5 5.7 6.7 21.5 1.3 1 0 0 1 1 1 0 Rifin Lin-8 PF03353.15 CDJ70562.1 - 6.7 6.2 29.7 8.6 5.8 29.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist XAP5 PF04921.14 CDJ70562.1 - 7.3 6.3 18.8 9.2 6.0 18.8 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator CDK5_activator PF03261.15 CDJ70562.1 - 8.1 5.9 23.7 9.8 5.6 23.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein LRS4 PF10422.9 CDJ70563.1 - 0.0012 18.5 1.3 0.0015 18.2 1.3 1.2 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Spt20 PF12090.8 CDJ70563.1 - 0.14 11.8 6.3 0.17 11.4 6.3 1.1 1 0 0 1 1 1 0 Spt20 family CAS_CSE1 PF03378.15 CDJ70565.1 - 1.1e-36 126.3 8.9 1.1e-36 126.3 8.9 2.9 4 1 0 4 4 4 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 CDJ70565.1 - 5.3e-31 107.8 2.9 2.5e-28 99.0 0.2 4.6 3 1 0 3 3 3 1 Cse1 IBN_N PF03810.19 CDJ70565.1 - 3.1e-12 46.2 2.1 3.1e-12 46.2 2.1 6.1 7 0 0 7 7 7 1 Importin-beta N-terminal domain SUIM_assoc PF16619.5 CDJ70565.1 - 0.00031 20.7 0.0 0.00031 20.7 0.0 11.9 11 1 1 12 12 12 3 Unstructured region C-term to UIM in Ataxin3 Rotamase PF00639.21 CDJ70566.1 - 1e-09 39.2 5.2 1e-09 39.2 5.2 3.8 1 1 2 3 3 3 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CDJ70566.1 - 1e-08 35.7 2.2 1e-08 35.7 2.2 3.3 1 1 2 3 3 3 1 PPIC-type PPIASE domain Ndc1_Nup PF09531.10 CDJ70566.1 - 0.77 8.4 25.3 1 7.9 25.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CT47 PF15623.6 CDJ70566.1 - 0.8 9.5 22.5 0.31 10.8 0.8 2.0 2 0 0 2 2 2 0 Cancer/testis gene family 47 AAA_23 PF13476.6 CDJ70566.1 - 7 7.1 23.6 7.2 7.1 9.3 2.1 2 0 0 2 2 2 0 AAA domain Ins_P5_2-kin PF06090.12 CDJ70567.1 - 1.2e-15 57.7 1.9 1.2e-15 57.7 1.9 4.9 3 2 1 5 5 5 2 Inositol-pentakisphosphate 2-kinase Cwf_Cwc_15 PF04889.12 CDJ70568.1 - 2.5e-38 132.2 2.3 2.9e-38 132.0 2.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein End3 PF12761.7 CDJ70568.1 - 0.005 17.0 2.0 0.0081 16.3 2.0 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 MFAP1 PF06991.11 CDJ70568.1 - 0.03 14.2 6.3 0.052 13.4 6.3 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing NARP1 PF12569.8 CDJ70569.1 - 0.19 10.6 14.3 0.21 10.4 14.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 O-antigen_lig PF13425.6 CDJ70569.1 - 1.3 7.7 4.2 1.2 7.9 4.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Spt20 PF12090.8 CDJ70569.1 - 1.9 8.0 28.1 2.2 7.8 28.1 1.1 1 0 0 1 1 1 0 Spt20 family MecA PF05389.12 CDJ70569.1 - 2.6 7.6 12.3 3.1 7.4 12.3 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) FAM91_C PF14648.6 CDJ70569.1 - 3.7 6.3 10.2 4 6.2 10.2 1.0 1 0 0 1 1 1 0 FAM91 C-terminus BSMAP PF12280.8 CDJ70569.1 - 4.3 7.5 14.2 5 7.3 14.2 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein RR_TM4-6 PF06459.12 CDJ70569.1 - 7 6.4 17.1 8.6 6.1 17.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ70569.1 - 7.3 5.5 20.2 8 5.3 20.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TSGP1 PF07771.11 CDJ70569.1 - 8.1 6.6 14.6 2.2 8.5 11.0 1.8 2 0 0 2 2 2 0 Tick salivary peptide group 1 Spt20 PF12090.8 CDJ70570.1 - 0.00043 20.0 14.1 0.00053 19.7 14.1 1.1 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ70570.1 - 0.0023 18.0 14.8 0.0026 17.8 14.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ70570.1 - 0.0025 16.8 10.6 0.0031 16.5 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Otopetrin PF03189.13 CDJ70570.1 - 0.39 9.5 1.0 0.53 9.0 1.0 1.1 1 0 0 1 1 1 0 Otopetrin THOC2_N PF16134.5 CDJ70570.1 - 0.9 8.1 2.7 1.4 7.5 2.7 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus SWI-SNF_Ssr4 PF08549.10 CDJ70570.1 - 2.4 6.7 10.6 2.6 6.6 10.6 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF4554 PF15091.6 CDJ70570.1 - 3.1 6.6 9.7 4.1 6.2 9.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Ndc1_Nup PF09531.10 CDJ70570.1 - 4.8 5.7 11.2 5.5 5.6 11.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ70570.1 - 5.1 5.7 7.7 6.2 5.5 7.7 1.1 1 0 0 1 1 1 0 Presenilin CDK2AP PF09806.9 CDJ70570.1 - 6.3 6.8 16.9 10 6.1 16.9 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein ADK PF00406.22 CDJ70571.1 - 2.3e-16 60.3 0.0 1.5e-06 28.4 0.1 3.1 2 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CDJ70571.1 - 1.5e-10 41.7 0.2 1e-06 29.2 0.0 2.6 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 CDJ70571.1 - 0.00016 22.2 0.0 0.071 13.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CDJ70571.1 - 0.00047 20.3 2.2 0.0018 18.4 2.2 2.1 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 CDJ70571.1 - 0.0046 16.7 0.3 0.0072 16.1 0.3 1.4 1 0 0 1 1 1 1 Cytidylate kinase RskA PF10099.9 CDJ70571.1 - 0.0058 16.9 16.9 0.0058 16.9 16.9 1.6 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Glyco_hydro_9 PF00759.19 CDJ70571.1 - 0.43 10.0 2.7 0.58 9.5 2.7 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 TFIIA PF03153.13 CDJ70571.1 - 1.3 9.0 6.3 1.7 8.6 6.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ70571.1 - 1.3 9.2 7.4 2.9 8.0 7.4 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF3138 PF11336.8 CDJ70571.1 - 5.6 5.5 9.7 7.7 5.0 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) p25-alpha PF05517.12 CDJ70572.1 - 1.3e-30 106.6 0.0 2.2e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 p25-alpha RRM_1 PF00076.22 CDJ70573.1 - 2.6e-05 23.9 0.0 6.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ70573.1 - 0.00044 20.1 0.2 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif Dehydrin PF00257.19 CDJ70573.1 - 1.3 9.6 4.3 1.3 9.5 0.3 2.2 2 0 0 2 2 2 0 Dehydrin TFIIA PF03153.13 CDJ70573.1 - 4.9 7.0 26.0 1.1 9.1 1.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LMBR1 PF04791.16 CDJ70574.1 - 9.6 5.0 7.6 17 4.2 7.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SUIM_assoc PF16619.5 CDJ70575.1 - 5.3e-12 45.6 38.5 3.3e-06 27.1 0.0 7.1 5 2 1 6 6 6 3 Unstructured region C-term to UIM in Ataxin3 Auxin_canalis PF05703.11 CDJ70575.1 - 0.0079 16.2 22.1 0.0079 16.2 22.1 5.2 2 1 2 4 4 4 1 Auxin canalisation PDE6_gamma PF04868.12 CDJ70575.1 - 0.96 9.7 5.4 2.4 8.5 3.8 2.6 1 1 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit PH PF00169.29 CDJ70576.1 - 0.0032 18.0 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 PH domain SUIM_assoc PF16619.5 CDJ70576.1 - 0.094 12.8 32.0 0.72 10.0 6.4 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2076 PF09849.9 CDJ70576.1 - 0.16 12.0 24.2 0.079 13.0 19.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Ndc1_Nup PF09531.10 CDJ70576.1 - 0.26 9.9 10.0 0.021 13.5 5.3 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF3123 PF11321.8 CDJ70576.1 - 6.9 7.4 8.0 4.4 8.0 0.5 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3123) RskA PF10099.9 CDJ70577.1 - 8.4e-08 32.7 25.4 0.0045 17.3 14.0 3.8 3 1 0 3 3 3 2 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 CDJ70577.1 - 0.00024 20.3 14.6 0.0079 15.3 12.4 2.2 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor DUF2722 PF10846.8 CDJ70577.1 - 0.00053 19.1 4.2 0.00053 19.1 4.2 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ70577.1 - 0.0028 17.7 8.3 0.0028 17.7 8.3 3.2 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit DUF2052 PF09747.9 CDJ70577.1 - 0.048 13.8 24.3 0.11 12.6 0.3 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4770 PF15994.5 CDJ70577.1 - 0.071 13.3 34.2 0.35 11.1 8.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) Suf PF05843.14 CDJ70577.1 - 0.12 12.3 35.6 0.18 11.7 4.1 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Cyclase_polyket PF04673.12 CDJ70577.1 - 0.13 12.5 5.2 0.053 13.8 1.4 2.3 2 1 0 2 2 2 0 Polyketide synthesis cyclase Presenilin PF01080.17 CDJ70577.1 - 0.25 10.1 30.8 0.28 9.9 0.1 2.6 3 0 0 3 3 3 0 Presenilin Eapp_C PF10238.9 CDJ70577.1 - 0.27 11.3 0.1 0.27 11.3 0.1 3.3 2 1 0 2 2 1 0 E2F-associated phosphoprotein Renin_r PF07850.14 CDJ70577.1 - 0.31 11.7 0.0 0.31 11.7 0.0 3.4 3 0 0 3 3 3 0 Renin receptor-like protein AF-4 PF05110.13 CDJ70577.1 - 0.77 7.8 33.1 0.062 11.4 17.4 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DUF2828 PF11443.8 CDJ70577.1 - 0.8 7.7 22.7 0.66 8.0 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Apt1 PF10351.9 CDJ70577.1 - 1.3 7.8 12.1 1.6 7.5 7.8 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain FAM60A PF15396.6 CDJ70577.1 - 2.9 7.8 21.0 17 5.4 0.2 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Senescence_reg PF04520.13 CDJ70577.1 - 2.9 8.7 15.8 0.76 10.6 7.9 2.5 2 0 0 2 2 2 0 Senescence regulator DUF572 PF04502.13 CDJ70577.1 - 4.3 6.9 25.2 7.1 6.2 2.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) THOC2_N PF16134.5 CDJ70577.1 - 4.9 5.7 20.1 0.28 9.7 2.7 2.2 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus CDC45 PF02724.14 CDJ70577.1 - 7 4.8 25.2 5.6 5.1 16.3 2.3 2 0 0 2 2 2 0 CDC45-like protein LAP1C PF05609.12 CDJ70577.1 - 9.4 5.2 31.3 0.58 9.2 1.0 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) PI3K_1B_p101 PF10486.9 CDJ70578.1 - 0.11 10.3 17.9 0.15 9.8 17.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Utp14 PF04615.13 CDJ70578.1 - 1.1 7.7 28.8 1.6 7.2 28.8 1.2 1 0 0 1 1 1 0 Utp14 protein RPA43_OB PF17875.1 CDJ70578.1 - 1.7 9.3 14.9 3.4 8.3 2.6 3.1 4 0 0 4 4 4 0 RPA43 OB domain in RNA Pol I DUF4551 PF15087.6 CDJ70578.1 - 1.8 7.3 31.4 2.9 6.6 31.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CRT10 PF08728.10 CDJ70578.1 - 2.1 6.4 14.3 2.6 6.1 14.3 1.0 1 0 0 1 1 1 0 CRT10 BRF1 PF07741.13 CDJ70578.1 - 5.3 7.4 25.9 8.4 6.8 9.8 3.5 3 0 0 3 3 3 0 Brf1-like TBP-binding domain TFB6 PF17110.5 CDJ70578.1 - 8.6 6.1 9.8 8.5 6.1 1.9 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH HemX PF04375.14 CDJ70578.1 - 9.1 5.5 36.6 7.1 5.8 13.9 2.4 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Alba PF01918.21 CDJ70579.1 - 5.9e-13 48.4 0.0 1.1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 CDJ70579.1 - 0.58 10.1 3.5 2.3 8.2 0.0 3.2 3 1 1 4 4 4 0 Rpp20 subunit of nuclear RNase MRP and P DUF3446 PF11928.8 CDJ70579.1 - 7.7 6.9 12.2 5.6 7.3 5.1 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain SUIM_assoc PF16619.5 CDJ70579.1 - 10 6.3 15.6 8.2 6.6 6.6 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FA_desaturase PF00487.24 CDJ70580.1 - 0.032 14.1 0.4 0.036 13.9 0.4 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Wzy_C PF04932.15 CDJ70580.1 - 0.11 12.1 0.2 0.13 11.9 0.2 1.1 1 0 0 1 1 1 0 O-Antigen ligase DPRP PF04244.13 CDJ70581.1 - 0.099 12.5 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein FH2 PF02181.23 CDJ70584.1 - 5.8e-67 226.4 0.3 8.3e-67 225.9 0.3 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF5057 PF16480.5 CDJ70584.1 - 0.051 12.9 1.0 0.62 9.4 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5057) zf-CCCH PF00642.24 CDJ70585.1 - 6.3e-06 26.0 24.1 0.00035 20.4 1.8 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ70585.1 - 0.012 15.5 0.9 0.012 15.5 0.9 3.8 4 0 0 4 4 4 0 CCCH-type zinc finger # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria_necatrix-ENH001/GCA_000499385.1_ENH001_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria_necatrix-ENH001/GCA_000499385.1_ENH001_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria_necatrix-ENH001/GCA_000499385.1_ENH001_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria_necatrix-ENH001/GCA_000499385.1_ENH001_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 01:47:35 2019 # [ok]