# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RR_TM4-6 PF06459.12 CDJ45598.1 - 0.053 13.3 13.2 0.071 12.9 13.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NOD2_WH PF17779.1 CDJ45598.1 - 0.083 13.2 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 NOD2 winged helix domain DDHD PF02862.17 CDJ45598.1 - 0.2 11.8 7.8 0.27 11.4 7.8 1.2 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 CDJ45598.1 - 0.28 11.1 33.9 0.4 10.6 33.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ45598.1 - 0.3 10.0 16.3 0.36 9.8 16.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ45598.1 - 0.36 9.5 13.4 0.43 9.3 13.4 1.1 1 0 0 1 1 1 0 Presenilin Baculo_PP31 PF05311.11 CDJ45598.1 - 0.66 9.4 8.1 0.85 9.1 8.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF913 PF06025.12 CDJ45598.1 - 1.4 7.9 5.9 1.6 7.6 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2126 PF09899.9 CDJ45598.1 - 1.5 6.8 8.7 2.1 6.3 8.7 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) EOS1 PF12326.8 CDJ45598.1 - 2.3 8.1 3.9 3.3 7.6 3.9 1.1 1 0 0 1 1 1 0 N-glycosylation protein Band_3_cyto PF07565.13 CDJ45598.1 - 3.7 7.3 10.7 4.6 7.0 10.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 CDJ45598.1 - 3.8 7.5 9.6 4.9 7.1 9.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 CDJ45598.1 - 3.9 6.4 12.4 4.6 6.2 12.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CPSF100_C PF13299.6 CDJ45598.1 - 5.4 7.2 11.1 7.4 6.7 11.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SprA-related PF12118.8 CDJ45598.1 - 6.4 5.8 28.0 9.8 5.2 28.0 1.3 1 0 0 1 1 1 0 SprA-related family CCDC53 PF10152.9 CDJ45598.1 - 7.7 6.9 15.6 17 5.8 15.6 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF1980 PF09323.10 CDJ45598.1 - 8.4 6.3 8.0 12 5.8 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CAP PF00188.26 CDJ45600.1 - 0.069 14.0 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich secretory protein family DUF2374 PF09574.10 CDJ45604.1 - 0.12 12.2 2.5 0.21 11.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) CAP PF00188.26 CDJ45607.1 - 0.09 13.6 0.0 0.16 12.8 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ45608.1 - 0.029 15.2 0.1 0.05 14.4 0.1 1.3 1 0 0 1 1 1 0 Cysteine-rich secretory protein family DUF4012 PF13196.6 CDJ45610.1 - 0.055 13.9 0.0 0.088 13.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4012) CAP PF00188.26 CDJ45610.1 - 0.078 13.8 0.0 0.13 13.1 0.0 1.3 1 0 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ45612.1 - 0.15 12.9 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ45613.1 - 0.067 14.0 0.1 0.13 13.1 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CDJ45616.1 - 0.036 14.9 0.0 0.057 14.3 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family ARL2_Bind_BART PF11527.8 CDJ45617.1 - 0.046 13.8 0.1 0.077 13.1 0.1 1.3 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Lipocalin PF00061.23 CDJ45619.1 - 0.0055 16.9 0.0 0.0086 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Surface_antigen PF11054.8 CDJ45620.1 - 0.0099 15.6 1.1 0.016 14.9 0.2 1.8 2 0 0 2 2 2 1 Sporozoite TA4 surface antigen HNOBA PF07701.14 CDJ45620.1 - 0.12 11.7 0.1 0.21 11.0 0.1 1.5 1 1 0 1 1 1 0 Heme NO binding associated Hexapep_2 PF14602.6 CDJ45625.1 - 0.47 10.2 2.5 20 5.0 0.1 2.7 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF2374 PF09574.10 CDJ45625.1 - 1.1 9.2 3.1 2.3 8.1 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) Type_ISP_C PF18135.1 CDJ45629.1 - 0.0045 16.0 0.0 0.13 11.3 0.0 2.1 2 0 0 2 2 2 2 Type ISP C-terminal specificity domain T2SSJ PF11612.8 CDJ45633.1 - 0.057 13.6 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J DUF3333 PF11812.8 CDJ45635.1 - 0.011 15.9 0.0 5.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) CHU_C PF13585.6 CDJ45635.1 - 0.17 11.9 0.3 20 5.3 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of CHU protein family DUF4854 PF16146.5 CDJ45636.1 - 0.14 12.5 1.1 0.46 10.8 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4854) Ank_2 PF12796.7 CDJ45639.1 - 0.068 13.8 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Peptidase_C10 PF01640.17 CDJ45639.1 - 0.14 12.5 0.1 0.19 12.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase C10 family Hexapep_2 PF14602.6 CDJ45641.1 - 0.44 10.4 2.2 6.2 6.7 0.2 2.9 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase RelB PF04221.12 CDJ45644.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 RelB antitoxin MoCF_biosynth PF00994.24 CDJ45645.1 - 0.048 13.3 0.0 0.068 12.8 0.0 1.4 1 1 0 1 1 1 0 Probable molybdopterin binding domain Cadherin-like PF12733.7 CDJ45645.1 - 0.12 12.9 0.2 0.2 12.2 0.2 1.3 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain GH97_C PF14509.6 CDJ45646.1 - 0.028 14.6 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation DUF937 PF06078.11 CDJ45652.1 - 0.14 12.7 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) Kinesin PF00225.23 CDJ45654.1 - 2.5e-77 260.1 0.0 2.5e-77 260.1 0.0 4.0 4 2 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ45654.1 - 2.7e-21 76.1 0.1 1.8e-16 60.4 0.0 3.9 2 1 1 3 3 3 2 Microtubule binding COE1_DBD PF16422.5 CDJ45655.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain Surface_antigen PF11054.8 CDJ45658.1 - 7.1e-46 156.9 0.2 1.1e-45 156.3 0.2 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45659.1 - 1.8e-77 260.3 3.7 2.1e-77 260.1 3.7 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45660.1 - 1.9e-63 214.4 6.4 1.5e-62 211.4 6.4 1.9 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45661.1 - 3.7e-58 197.1 8.2 6.3e-48 163.6 3.0 2.1 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45662.1 - 3.2e-76 256.2 8.1 4.8e-52 177.1 3.1 3.1 1 1 2 3 3 3 3 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45663.1 - 9.5e-49 166.3 0.7 1.2e-48 166.0 0.7 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45664.1 - 6.3e-70 235.6 1.8 7.8e-70 235.3 1.8 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45665.1 - 1.6e-124 414.4 16.4 1.2e-81 274.0 2.2 2.7 2 1 0 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45666.1 - 7.2e-95 317.3 18.2 8.2e-45 153.4 2.8 4.7 3 1 1 4 4 4 4 Sporozoite TA4 surface antigen OmdA PF13376.6 CDJ45666.1 - 0.0034 17.3 0.0 0.6 10.2 0.0 2.5 2 0 0 2 2 2 2 Bacteriocin-protection, YdeI or OmpD-Associated Surface_antigen PF11054.8 CDJ45667.1 - 1.9e-71 240.6 2.2 2.2e-71 240.4 2.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45668.1 - 1.3e-68 231.3 4.6 9.2e-67 225.2 4.6 2.1 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen CDC73_C PF05179.14 CDJ45668.1 - 0.058 13.1 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 RNA pol II accessory factor, Cdc73 family, C-terminal DUF4653 PF15546.6 CDJ45668.1 - 0.19 11.3 0.1 0.37 10.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4653) Surface_antigen PF11054.8 CDJ45669.1 - 1.4e-68 231.2 1.0 1.6e-68 231.0 1.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen GCD14 PF08704.10 CDJ45670.1 - 9.2e-47 159.8 0.0 4.4e-29 101.9 0.0 2.6 2 1 1 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CDJ45670.1 - 8.8e-07 28.8 0.0 1.1e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDJ45670.1 - 0.00028 20.7 0.0 0.0006 19.6 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CDJ45670.1 - 0.0062 17.2 0.0 0.016 15.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ45670.1 - 0.016 14.5 0.0 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 CDJ45670.1 - 0.05 14.6 0.0 0.096 13.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 CDJ45670.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 CDJ45670.1 - 0.14 11.7 0.0 0.61 9.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Surface_antigen PF11054.8 CDJ45671.1 - 1.4e-76 257.4 0.0 1.6e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45672.1 - 1.8e-121 404.4 16.6 8.1e-71 238.5 6.8 2.1 2 0 0 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45673.1 - 6.4e-72 242.1 8.7 7.7e-72 241.9 8.7 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF2385 PF09539.10 CDJ45673.1 - 0.39 11.3 1.8 8.3 7.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2385) Surface_antigen PF11054.8 CDJ45674.1 - 1.2e-73 247.8 5.5 1.5e-73 247.5 5.5 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen PsiA PF06952.11 CDJ45674.1 - 0.016 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 PsiA protein Surface_antigen PF11054.8 CDJ45675.1 - 4.5e-72 242.6 4.4 5.7e-72 242.3 4.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45676.1 - 4.5e-75 252.4 5.1 5.4e-75 252.2 5.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen PsiA PF06952.11 CDJ45676.1 - 0.011 15.0 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 PsiA protein Surface_antigen PF11054.8 CDJ45677.1 - 8.2e-74 248.3 4.2 1e-73 248.0 4.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45678.1 - 1.3e-77 260.8 3.3 1.5e-77 260.6 3.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45679.1 - 4.5e-71 239.4 3.1 8.5e-71 238.5 3.1 1.4 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen ODAPH PF15848.5 CDJ45679.1 - 0.38 11.2 1.3 8.5 6.9 0.1 2.4 2 0 0 2 2 2 0 Odontogenesis associated phosphoprotein Surface_antigen PF11054.8 CDJ45680.1 - 1.3e-76 257.5 5.4 1.5e-76 257.3 5.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen PsiA PF06952.11 CDJ45680.1 - 0.042 13.1 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 PsiA protein UPF0223 PF05256.12 CDJ45680.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0223) Surface_antigen PF11054.8 CDJ45681.1 - 2.6e-76 256.5 7.5 3.1e-76 256.3 7.5 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45682.1 - 3.3e-68 230.0 3.1 4e-68 229.7 3.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ45683.1 - 2.7e-64 217.2 1.8 3.3e-64 216.9 1.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen ABC_tran PF00005.27 CDJ45684.1 - 1.8e-33 115.9 0.0 5.1e-33 114.5 0.0 1.8 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 CDJ45684.1 - 2.2e-23 83.3 8.0 4.3e-23 82.3 8.0 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 CDJ45684.1 - 0.00014 21.8 0.1 0.0097 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CDJ45684.1 - 0.00048 20.6 1.1 0.0012 19.3 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 CDJ45684.1 - 0.00091 18.7 0.0 0.011 15.1 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF815 PF05673.13 CDJ45684.1 - 0.0079 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 CDJ45684.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 CDJ45684.1 - 0.013 15.7 0.1 0.045 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CDJ45684.1 - 0.02 14.6 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CDJ45684.1 - 0.032 13.8 1.3 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ45684.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DLIC PF05783.11 CDJ45684.1 - 0.052 12.4 0.0 0.052 12.4 0.0 1.8 2 0 0 2 2 1 0 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 CDJ45684.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CDJ45684.1 - 0.12 12.8 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CDJ45684.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase DUF1385 PF07136.11 CDJ45684.1 - 0.14 11.5 2.1 0.52 9.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) AAA_15 PF13175.6 CDJ45684.1 - 0.21 11.2 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.12 CDJ45684.1 - 0.24 10.8 0.0 0.57 9.6 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein L51_S25_CI-B8 PF05047.16 CDJ45685.1 - 0.00061 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DAGAT PF03982.13 CDJ45686.1 - 6.5e-27 94.2 0.0 7.2e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF5027 PF16430.5 CDJ45686.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5027) Pkinase PF00069.25 CDJ45688.1 - 4.6e-60 203.2 0.0 5.1e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ45688.1 - 2.6e-33 115.4 0.0 3.1e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ45688.1 - 1.1e-06 28.2 0.2 7.6e-06 25.5 0.1 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDJ45688.1 - 1.5e-05 24.1 0.9 2.6e-05 23.4 0.9 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDJ45688.1 - 0.0014 18.1 1.2 0.0026 17.2 1.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ45688.1 - 0.0052 16.7 0.3 0.75 9.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ45688.1 - 0.12 11.2 0.1 0.43 9.3 0.0 1.9 2 1 0 2 2 2 0 Fungal protein kinase Histone_HNS PF00816.21 CDJ45689.1 - 0.2 12.5 0.1 0.2 12.5 0.1 3.1 1 1 1 2 2 2 0 H-NS histone family Ins145_P3_rec PF08709.11 CDJ45690.1 - 0.1 11.8 0.1 0.22 10.7 0.0 1.5 1 1 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor AAA_2 PF07724.14 CDJ45691.1 - 1.3e-37 129.5 0.1 4e-37 128.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 CDJ45691.1 - 6.9e-14 51.7 0.0 1.9e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_lid_9 PF17871.1 CDJ45691.1 - 1.5e-09 37.7 1.1 3.4e-09 36.6 1.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 CDJ45691.1 - 3.7e-08 33.4 0.0 3.1e-07 30.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ45691.1 - 2.3e-07 31.3 0.0 5.3e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ45691.1 - 8.9e-07 28.8 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 CDJ45691.1 - 0.00046 19.5 0.0 0.00087 18.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.12 CDJ45691.1 - 0.009 15.8 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CDJ45691.1 - 0.022 15.3 0.0 0.082 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CDJ45691.1 - 0.025 14.8 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CDJ45691.1 - 0.031 14.6 0.2 2.2 8.6 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ45691.1 - 0.037 14.4 0.1 0.36 11.2 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.6 CDJ45691.1 - 0.071 13.1 0.9 0.33 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 CDJ45691.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Torsin Bac_DnaA PF00308.18 CDJ45691.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein RsgA_GTPase PF03193.16 CDJ45691.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ASFV_J13L PF05568.11 CDJ45691.1 - 0.84 9.4 3.8 1.6 8.4 3.8 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Syntaphilin PF15290.6 CDJ45691.1 - 4.6 6.8 10.4 15 5.1 9.2 2.1 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp DUF1117 PF06547.12 CDJ45691.1 - 7.9 7.1 11.0 19 5.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) SpoIIIAH PF12685.7 CDJ45692.1 - 0.21 11.4 16.6 0.24 11.2 16.6 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein AAA_2 PF07724.14 CDJ45693.1 - 3.6e-25 89.0 0.1 1e-15 58.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 CDJ45693.1 - 4.2e-15 55.5 0.6 1.2e-14 54.1 0.1 2.1 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein Torsin PF06309.11 CDJ45693.1 - 8.8e-05 22.6 0.0 0.00032 20.8 0.0 1.9 2 0 0 2 2 2 1 Torsin AAA_16 PF13191.6 CDJ45693.1 - 0.00017 22.0 0.0 0.00033 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 CDJ45693.1 - 0.00031 20.1 0.0 0.00064 19.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 CDJ45693.1 - 0.0011 19.4 0.0 0.0039 17.6 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ45693.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 CDJ45693.1 - 0.0024 18.4 0.0 0.0062 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CDJ45693.1 - 0.0029 17.5 0.0 0.069 13.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase DNA_pol3_delta2 PF13177.6 CDJ45693.1 - 0.0049 16.7 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase III, delta subunit IstB_IS21 PF01695.17 CDJ45693.1 - 0.014 15.2 0.0 0.05 13.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CDJ45693.1 - 0.015 15.7 0.1 0.15 12.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 CDJ45693.1 - 0.017 15.3 0.0 0.053 13.7 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 CDJ45693.1 - 0.024 13.8 0.1 0.047 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MbeB_N PF04837.12 CDJ45693.1 - 0.032 14.5 0.6 0.27 11.6 0.0 2.6 2 0 0 2 2 2 0 MbeB-like, N-term conserved region AAA_5 PF07728.14 CDJ45693.1 - 0.039 14.0 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDJ45693.1 - 0.04 13.7 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 CDJ45693.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF87 PF01935.17 CDJ45693.1 - 0.057 13.5 0.3 0.17 11.9 0.3 1.9 1 1 0 1 1 1 0 Helicase HerA, central domain ABC_tran PF00005.27 CDJ45693.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 CDJ45693.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CDJ45693.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ45693.1 - 0.15 12.3 0.0 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ThiF PF00899.21 CDJ45695.1 - 5.4e-05 22.7 0.0 0.00067 19.1 0.0 2.2 2 1 0 2 2 2 1 ThiF family DEAD PF00270.29 CDJ45696.1 - 1.5e-13 50.9 0.3 2.5e-12 46.9 0.0 2.8 3 0 0 3 3 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ45696.1 - 6.5e-05 23.0 0.0 6.5e-05 23.0 0.0 2.8 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit SDA1 PF05285.12 CDJ45696.1 - 0.0046 16.4 20.0 0.0078 15.7 20.0 1.4 1 0 0 1 1 1 1 SDA1 PorA PF11271.8 CDJ45696.1 - 0.0056 16.0 8.4 0.0056 16.0 8.4 2.6 3 0 0 3 3 3 1 Porin PorA DUF2722 PF10846.8 CDJ45696.1 - 0.0073 15.3 0.1 0.0073 15.3 0.1 3.3 2 1 1 3 3 2 1 Protein of unknown function (DUF2722) CDC45 PF02724.14 CDJ45696.1 - 0.028 12.7 20.3 0.042 12.2 20.3 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.6 CDJ45696.1 - 0.63 10.0 24.1 0.43 10.5 19.8 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DUF908 PF06012.12 CDJ45696.1 - 2.2 7.6 16.0 25 4.1 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) RR_TM4-6 PF06459.12 CDJ45696.1 - 2.4 7.9 29.5 3.9 7.2 26.6 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Hamartin PF04388.12 CDJ45696.1 - 2.8 6.5 21.6 4.3 5.9 21.6 1.2 1 0 0 1 1 1 0 Hamartin protein SID-1_RNA_chan PF13965.6 CDJ45696.1 - 6.3 5.1 10.0 11 4.3 10.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIA PF03153.13 CDJ45697.1 - 4.2e-05 23.7 57.4 0.0011 19.0 33.1 2.0 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 CDJ45697.1 - 8.8e-05 21.1 8.1 0.0071 14.8 2.5 2.1 2 0 0 2 2 2 2 dsRNA-gated channel SID-1 Phage_holin_3_6 PF07332.11 CDJ45697.1 - 0.00019 21.5 13.5 0.0013 18.7 5.7 3.1 3 0 0 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4834 PF16118.5 CDJ45697.1 - 0.00021 22.2 27.7 0.026 15.5 3.7 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4834) EPL1 PF10513.9 CDJ45697.1 - 0.0032 17.9 25.2 0.14 12.6 2.1 2.3 2 0 0 2 2 2 2 Enhancer of polycomb-like Spt20 PF12090.8 CDJ45697.1 - 0.0034 17.0 62.5 0.026 14.1 36.3 2.2 2 0 0 2 2 2 2 Spt20 family V_ATPase_I PF01496.19 CDJ45697.1 - 0.0065 14.5 12.0 0.31 8.9 0.2 2.2 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family O-antigen_lig PF13425.6 CDJ45697.1 - 0.016 14.0 4.7 0.33 9.7 2.3 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Ctr PF04145.15 CDJ45697.1 - 0.017 15.7 19.9 0.02 15.5 0.8 2.6 2 1 0 2 2 2 0 Ctr copper transporter family MAP17 PF15807.5 CDJ45697.1 - 0.019 15.2 11.8 0.31 11.3 0.6 2.4 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Lipase_GDSL PF00657.22 CDJ45697.1 - 0.032 14.2 0.3 0.032 14.2 0.3 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase NEMP PF10225.9 CDJ45697.1 - 0.036 13.7 12.4 0.52 9.9 2.2 2.2 2 0 0 2 2 2 0 NEMP family EMC3_TMCO1 PF01956.16 CDJ45697.1 - 0.04 13.6 0.0 0.04 13.6 0.0 2.5 2 1 0 2 2 1 0 Integral membrane protein EMC3/TMCO1-like Med15 PF09606.10 CDJ45697.1 - 0.045 12.5 41.1 0.016 14.0 21.8 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal SLC12 PF03522.15 CDJ45697.1 - 0.068 12.2 23.5 0.28 10.2 1.4 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 CDJ45697.1 - 0.1 12.7 21.7 0.24 11.5 1.6 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family FA_desaturase PF00487.24 CDJ45697.1 - 0.16 11.8 0.1 2.4 7.9 0.0 2.5 3 0 0 3 3 3 0 Fatty acid desaturase FAM76 PF16046.5 CDJ45697.1 - 0.17 11.2 25.2 0.13 11.6 3.0 2.1 2 0 0 2 2 2 0 FAM76 protein Miga PF10265.9 CDJ45697.1 - 0.2 10.6 26.3 0.96 8.3 14.2 2.0 2 0 0 2 2 2 0 Mitoguardin WBP-1 PF11669.8 CDJ45697.1 - 0.21 12.3 0.1 0.21 12.3 0.1 2.9 2 1 0 2 2 1 0 WW domain-binding protein 1 Roughex PF06020.11 CDJ45697.1 - 0.28 10.2 27.7 0.011 14.8 10.3 2.2 2 0 0 2 2 2 0 Drosophila roughex protein MPM1 PF17234.2 CDJ45697.1 - 0.31 11.3 27.1 0.92 9.7 4.1 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 RskA PF10099.9 CDJ45697.1 - 0.33 11.2 56.8 1.1 9.5 28.8 4.0 1 1 2 3 3 2 0 Anti-sigma-K factor rskA AAA_23 PF13476.6 CDJ45697.1 - 0.33 11.4 17.7 0.09 13.3 4.4 2.2 2 0 0 2 2 2 0 AAA domain Ndc1_Nup PF09531.10 CDJ45697.1 - 0.35 9.5 35.2 0.34 9.5 5.9 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF2828 PF11443.8 CDJ45697.1 - 0.44 8.6 20.6 0.18 9.8 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Mcm10 PF09332.11 CDJ45697.1 - 0.49 9.8 31.3 0.041 13.3 6.7 2.1 2 0 0 2 2 2 0 Mcm10 replication factor ETRAMP PF09716.10 CDJ45697.1 - 0.66 10.1 0.0 0.66 10.1 0.0 4.3 3 2 1 4 4 3 0 Malarial early transcribed membrane protein (ETRAMP) NUDE_C PF04880.13 CDJ45697.1 - 0.71 10.3 24.1 0.037 14.5 6.7 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region DUF913 PF06025.12 CDJ45697.1 - 1.4 7.9 19.6 0.48 9.4 10.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 CDJ45697.1 - 1.4 9.0 27.0 0.62 10.2 12.9 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal BORG_CEP PF14957.6 CDJ45697.1 - 1.5 10.0 24.8 0.35 12.0 5.9 2.2 2 0 0 2 2 2 0 Cdc42 effector SRP-alpha_N PF04086.13 CDJ45697.1 - 1.6 8.6 30.9 0.77 9.6 4.8 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal OSTbeta PF15048.6 CDJ45697.1 - 1.6 8.9 11.3 6.1 7.0 6.3 2.8 2 1 1 3 3 3 0 Organic solute transporter subunit beta protein eIF-3_zeta PF05091.12 CDJ45697.1 - 1.8 7.4 32.5 1.1 8.1 16.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Otopetrin PF03189.13 CDJ45697.1 - 1.9 7.2 10.6 1.8 7.3 3.8 2.3 2 0 0 2 2 2 0 Otopetrin PA26 PF04636.13 CDJ45697.1 - 2 7.2 20.1 2.6 6.9 11.9 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Lin-8 PF03353.15 CDJ45697.1 - 2.2 7.7 37.2 0.76 9.3 11.0 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist MMR1 PF08505.10 CDJ45697.1 - 2.4 8.4 37.4 0.87 9.8 16.3 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Velvet PF11754.8 CDJ45697.1 - 2.5 8.0 26.1 1.7 8.5 8.5 2.2 2 0 0 2 2 2 0 Velvet factor FAM176 PF14851.6 CDJ45697.1 - 2.8 7.6 18.9 1.3 8.6 0.4 2.6 2 1 0 2 2 2 0 FAM176 family DUF4446 PF14584.6 CDJ45697.1 - 2.8 7.9 11.6 3.1 7.8 2.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) SARAF PF06682.12 CDJ45697.1 - 3 7.4 26.3 0.041 13.5 1.6 2.6 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SAGA-Tad1 PF12767.7 CDJ45697.1 - 3 7.5 22.2 1 9.1 2.4 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit GPCR_chapero_1 PF11904.8 CDJ45697.1 - 3.5 7.0 20.8 1.7 8.0 11.7 2.1 2 0 0 2 2 2 0 GPCR-chaperone RR_TM4-6 PF06459.12 CDJ45697.1 - 4.2 7.1 31.4 0.5 10.1 16.7 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4199 PF13858.6 CDJ45697.1 - 4.5 7.7 0.0 4.5 7.7 0.0 3.3 2 1 0 2 2 1 0 Protein of unknown function (DUF4199) DUF2151 PF10221.9 CDJ45697.1 - 4.6 5.7 18.8 0.3 9.6 1.2 2.0 2 0 0 2 2 2 0 Cell cycle and development regulator 2HCT PF03390.15 CDJ45697.1 - 4.6 5.8 11.7 0.32 9.6 5.2 2.2 2 1 1 3 3 3 0 2-hydroxycarboxylate transporter family NST1 PF13945.6 CDJ45697.1 - 4.6 7.3 43.3 2.7 8.1 24.6 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator GREB1 PF15782.5 CDJ45697.1 - 4.8 4.2 35.2 0.49 7.5 11.2 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer VIT1 PF01988.19 CDJ45697.1 - 4.9 7.0 20.5 12 5.7 16.3 2.5 2 0 0 2 2 2 0 VIT family DUF2052 PF09747.9 CDJ45697.1 - 6.2 6.9 25.9 6.6 6.8 2.7 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4554 PF15091.6 CDJ45697.1 - 6.7 5.5 21.8 1.4 7.7 11.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4554) HA2 PF04408.23 CDJ45697.1 - 7 7.0 22.5 0.42 10.9 7.2 3.2 2 1 1 3 3 3 0 Helicase associated domain (HA2) CHD5 PF04420.14 CDJ45697.1 - 7.2 6.4 23.7 1 9.2 4.8 2.4 2 0 0 2 2 2 0 CHD5-like protein Sporozoite_P67 PF05642.11 CDJ45697.1 - 8.8 4.3 24.6 0.43 8.6 8.9 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen ALMT PF11744.8 CDJ45697.1 - 8.9 5.0 24.7 1.2 7.8 11.1 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ45697.1 - 9.4 4.4 41.5 0.82 7.9 22.0 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 YABBY PF04690.13 CDJ45697.1 - 9.9 6.7 21.3 1.9 9.0 9.1 2.2 2 0 0 2 2 2 0 YABBY protein RskA PF10099.9 CDJ45698.1 - 6.4e-08 33.1 15.5 4.7e-07 30.3 8.8 2.8 2 1 0 2 2 2 2 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ45698.1 - 4.6e-05 23.2 3.8 4.6e-05 23.2 3.8 3.5 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein Dpy19 PF10034.9 CDJ45698.1 - 0.003 15.9 8.0 0.0059 14.9 8.0 1.4 1 1 0 1 1 1 1 Q-cell neuroblast polarisation AIF_C PF14721.6 CDJ45698.1 - 0.0035 17.7 0.9 0.0035 17.7 0.9 3.8 3 1 0 3 3 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Spt20 PF12090.8 CDJ45698.1 - 0.013 15.1 28.2 0.013 15.1 28.2 3.1 3 0 0 3 3 3 0 Spt20 family DUF775 PF05603.12 CDJ45698.1 - 0.014 15.0 4.2 0.014 15.0 4.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF775) TERB2 PF15101.6 CDJ45698.1 - 0.022 14.8 9.5 0.022 14.8 9.5 3.3 3 1 0 3 3 3 0 Telomere-associated protein TERB2 Peptidase_S49_N PF08496.10 CDJ45698.1 - 0.029 14.4 1.4 0.029 14.4 1.4 2.7 3 0 0 3 3 3 0 Peptidase family S49 N-terminal DUF2828 PF11443.8 CDJ45698.1 - 2.1 6.3 16.4 0.011 13.9 5.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) TCP PF03634.13 CDJ45698.1 - 2.2 8.8 33.8 0.039 14.5 8.4 3.2 3 0 0 3 3 3 0 TCP family transcription factor FAM176 PF14851.6 CDJ45698.1 - 2.3 7.9 18.6 0.19 11.3 3.9 3.2 3 0 0 3 3 3 0 FAM176 family CCDC53 PF10152.9 CDJ45698.1 - 5.6 7.4 28.6 0.11 13.0 5.5 3.3 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex WD40 PF00400.32 CDJ45699.1 - 9e-60 197.2 18.1 3.8e-09 37.0 0.0 10.1 9 1 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ45699.1 - 5.7e-26 90.7 0.0 0.00046 20.4 0.0 5.4 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ45699.1 - 2.9e-06 27.3 0.0 0.069 13.0 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDJ45699.1 - 1.2e-05 24.5 0.0 0.24 10.3 0.0 4.1 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SPX PF03105.19 CDJ45699.1 - 0.0031 17.5 33.7 0.11 12.4 19.2 2.2 2 0 0 2 2 2 2 SPX domain SR-25 PF10500.9 CDJ45699.1 - 0.0078 15.8 81.0 0.15 11.6 8.9 3.5 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein Frtz PF11768.8 CDJ45699.1 - 0.039 12.3 0.0 2.7 6.2 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Mcm10 PF09332.11 CDJ45699.1 - 6.2 6.2 31.7 0.22 10.9 18.9 2.2 2 0 0 2 2 2 0 Mcm10 replication factor zf-CCHC_2 PF13696.6 CDJ45700.1 - 1.1e-07 31.5 3.5 1.7e-07 30.9 3.5 1.3 1 0 0 1 1 1 1 Zinc knuckle SUIM_assoc PF16619.5 CDJ45700.1 - 1.9e-05 24.6 0.2 1.9e-05 24.6 0.2 5.4 3 2 0 3 3 2 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ45700.1 - 0.0036 17.0 49.6 0.086 12.4 10.9 3.4 3 0 0 3 3 3 2 Spt20 family zf-CCHC PF00098.23 CDJ45700.1 - 0.0093 16.0 5.2 0.018 15.1 5.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ45700.1 - 0.18 11.5 2.8 0.32 10.8 2.8 1.3 1 0 0 1 1 1 0 Zinc knuckle AAA_23 PF13476.6 CDJ45700.1 - 0.27 11.7 13.9 0.32 11.5 0.7 2.3 2 0 0 2 2 2 0 AAA domain MPM1 PF17234.2 CDJ45700.1 - 1.1 9.6 14.5 3.5 7.9 1.3 2.7 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF3381 PF11861.8 CDJ45700.1 - 1.7 8.4 13.5 1.9 8.3 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) CIAPIN1 PF05093.13 CDJ45700.1 - 4.3 7.9 9.0 20 5.8 1.8 2.9 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF4642 PF15484.6 CDJ45700.1 - 5.1 7.3 10.6 0.27 11.5 0.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4642) tRNA_lig_CPD PF08302.11 CDJ45700.1 - 6.1 6.2 12.9 1.6 8.1 2.2 2.5 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain V_ATPase_I PF01496.19 CDJ45700.1 - 6.1 4.6 14.0 1.6 6.5 3.3 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family ERAP1_C PF11838.8 CDJ45703.1 - 0.046 13.3 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 ERAP1-like C-terminal domain RRN3 PF05327.11 CDJ45703.1 - 1 7.8 6.1 1.5 7.3 6.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EF-hand_8 PF13833.6 CDJ45704.1 - 0.005 16.7 1.3 0.083 12.7 0.2 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 CDJ45704.1 - 0.0076 16.7 0.0 0.032 14.7 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ45704.1 - 0.14 11.8 0.0 0.7 9.6 0.0 2.3 1 0 0 1 1 1 0 EF hand VIT1 PF01988.19 CDJ45704.1 - 2 8.3 10.2 0.29 11.0 5.9 1.7 1 1 1 2 2 2 0 VIT family Peptidase_S48 PF03574.15 CDJ45705.1 - 0.17 12.1 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S48 Epimerase PF01370.21 CDJ45706.1 - 2.9 7.3 20.2 4.3 6.7 0.1 5.8 5 2 1 7 7 7 0 NAD dependent epimerase/dehydratase family YEATS PF03366.16 CDJ45706.1 - 8.9 6.4 13.4 24 5.0 0.0 6.4 6 2 1 7 7 7 0 YEATS family CS PF04969.16 CDJ45707.1 - 7.7e-06 26.8 0.0 1.1e-05 26.3 0.0 1.2 1 0 0 1 1 1 1 CS domain Forkhead_N PF08430.12 CDJ45707.1 - 0.024 15.3 0.6 0.031 14.9 0.6 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region DUF2722 PF10846.8 CDJ45709.1 - 0.0012 17.9 12.9 0.0012 17.8 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pinin_SDK_memA PF04696.13 CDJ45709.1 - 0.015 15.4 15.0 0.026 14.6 14.3 1.6 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region EIIBC-GUT_N PF03612.14 CDJ45709.1 - 0.015 15.1 4.4 0.02 14.6 4.4 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Hydrolase_4 PF12146.8 CDJ45709.1 - 0.043 13.1 0.1 0.087 12.1 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF4770 PF15994.5 CDJ45709.1 - 0.047 13.9 5.6 0.056 13.7 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) eIF3_subunit PF08597.10 CDJ45709.1 - 0.069 13.0 5.8 0.088 12.7 5.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Presenilin PF01080.17 CDJ45709.1 - 0.096 11.4 4.1 0.12 11.2 4.1 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ45709.1 - 0.24 11.2 9.2 0.3 10.9 9.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4834 PF16118.5 CDJ45709.1 - 0.31 12.0 11.8 0.49 11.4 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) dsDNA_bind PF01984.20 CDJ45709.1 - 0.34 11.2 18.5 0.48 10.7 18.5 1.2 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Abhydrolase_1 PF00561.20 CDJ45709.1 - 0.53 9.9 0.1 0.53 9.9 0.1 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Renin_r PF07850.14 CDJ45709.1 - 0.66 10.6 3.2 1 10.0 3.2 1.2 1 0 0 1 1 1 0 Renin receptor-like protein PRC2_HTH_1 PF18118.1 CDJ45709.1 - 0.89 10.4 5.4 1.3 9.8 5.4 1.2 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain MMR1 PF08505.10 CDJ45709.1 - 1.1 9.6 9.5 1.3 9.2 9.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Neur_chan_memb PF02932.16 CDJ45709.1 - 1.5 8.8 4.3 2.1 8.4 4.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF775 PF05603.12 CDJ45709.1 - 2.2 7.7 9.2 3 7.3 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) CCDC53 PF10152.9 CDJ45709.1 - 3.4 8.1 10.1 5 7.5 10.1 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CLN3 PF02487.17 CDJ45709.1 - 3.6 6.5 4.8 4.9 6.1 4.8 1.1 1 0 0 1 1 1 0 CLN3 protein DUF2828 PF11443.8 CDJ45709.1 - 4.7 5.2 8.7 6.4 4.7 8.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Connexin PF00029.19 CDJ45709.1 - 5.8 6.6 5.8 7.9 6.2 5.8 1.1 1 0 0 1 1 1 0 Connexin Med15 PF09606.10 CDJ45709.1 - 5.8 5.5 22.1 6.6 5.3 22.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TERB2 PF15101.6 CDJ45709.1 - 6 6.9 13.7 9.1 6.3 13.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TMEM51 PF15345.6 CDJ45709.1 - 7.1 6.4 13.3 10 5.8 13.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 V_ATPase_I PF01496.19 CDJ45709.1 - 8.7 4.1 8.4 9.8 3.9 8.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MscS_TM PF12794.7 CDJ45709.1 - 9 5.1 13.3 12 4.6 13.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 CCDC158 PF15921.5 CDJ45710.1 - 1.8 6.3 3.8 1.8 6.3 3.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 DUF4407 PF14362.6 CDJ45711.1 - 0.00074 19.0 22.6 0.0009 18.7 22.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) PAT1 PF09770.9 CDJ45711.1 - 0.0073 14.6 25.6 0.0078 14.6 25.6 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 CDJ45711.1 - 0.011 15.4 41.8 0.15 11.7 11.1 2.1 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ45711.1 - 0.012 14.6 30.8 0.029 13.3 4.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Apc15p PF05841.11 CDJ45711.1 - 0.022 15.6 14.7 0.13 13.0 5.9 2.1 2 0 0 2 2 2 0 Apc15p protein Presenilin PF01080.17 CDJ45711.1 - 0.046 12.5 12.2 0.061 12.1 12.2 1.1 1 0 0 1 1 1 0 Presenilin RLL PF10036.9 CDJ45711.1 - 0.057 13.3 14.4 0.34 10.7 4.5 2.1 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein DUF2828 PF11443.8 CDJ45711.1 - 0.08 11.0 6.9 0.11 10.6 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PIP5K PF01504.18 CDJ45711.1 - 0.21 10.8 6.0 0.32 10.2 6.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase NPR1_interact PF15699.5 CDJ45711.1 - 0.21 12.2 13.0 1.5 9.4 2.6 2.2 2 0 0 2 2 2 0 NPR1 interacting CAF1 PF04857.20 CDJ45711.1 - 0.25 10.5 6.1 0.33 10.1 6.1 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease SpoIIP PF07454.11 CDJ45711.1 - 0.31 10.5 12.1 0.43 10.0 2.4 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4834 PF16118.5 CDJ45711.1 - 0.32 12.0 18.0 2.4 9.2 6.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2859 PF11072.8 CDJ45711.1 - 0.37 10.5 9.9 0.93 9.2 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) Rrp15p PF07890.12 CDJ45711.1 - 0.49 10.7 17.5 0.32 11.3 6.5 2.3 2 0 0 2 2 2 0 Rrp15p DUF702 PF05142.12 CDJ45711.1 - 0.57 10.7 14.5 3.9 7.9 7.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Band_3_cyto PF07565.13 CDJ45711.1 - 0.65 9.7 10.0 1.7 8.4 2.2 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain tRNA_synt_1c_R2 PF04557.15 CDJ45711.1 - 0.74 10.8 11.9 2.9 8.9 1.0 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Rxt3 PF08642.10 CDJ45711.1 - 0.79 10.5 8.2 7.3 7.4 1.9 2.1 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 MAT1 PF06391.13 CDJ45711.1 - 0.95 9.2 19.5 0.48 10.2 6.8 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 dsRBD2 PF17842.1 CDJ45711.1 - 1 9.5 7.5 1.6 8.9 2.0 2.1 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 DUF4050 PF13259.6 CDJ45711.1 - 1.3 9.3 13.7 2.2 8.5 13.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) DUF3464 PF11947.8 CDJ45711.1 - 1.3 8.7 17.4 1.7 8.4 2.8 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Connexin PF00029.19 CDJ45711.1 - 1.4 8.6 7.5 2.9 7.6 1.8 2.1 2 0 0 2 2 2 0 Connexin Peptidase_S64 PF08192.11 CDJ45711.1 - 1.4 7.3 5.9 3 6.2 0.6 2.0 2 0 0 2 2 2 0 Peptidase family S64 DUF1676 PF07898.13 CDJ45711.1 - 1.5 8.9 4.0 22 5.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Thg1C PF14413.6 CDJ45711.1 - 1.5 9.0 10.7 1.6 8.9 2.2 2.1 2 0 0 2 2 2 0 Thg1 C terminal domain DUF3371 PF11851.8 CDJ45711.1 - 1.7 9.8 17.0 5 8.2 7.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) BRF1 PF07741.13 CDJ45711.1 - 1.9 8.9 17.3 2.2 8.7 8.2 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DDRGK PF09756.9 CDJ45711.1 - 2 8.0 23.6 3.1 7.3 5.4 2.1 2 0 0 2 2 2 0 DDRGK domain PTPRCAP PF15713.5 CDJ45711.1 - 2.4 8.4 16.8 1.2 9.4 4.1 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Nop53 PF07767.11 CDJ45711.1 - 2.6 7.4 24.5 0.37 10.1 9.9 2.0 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) THOC2_N PF16134.5 CDJ45711.1 - 3.3 6.2 8.2 4.3 5.8 8.2 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus EIIBC-GUT_N PF03612.14 CDJ45711.1 - 3.3 7.4 13.2 2.8 7.7 4.1 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4484 PF14831.6 CDJ45711.1 - 3.5 7.6 12.0 4.2 7.4 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Peroxin-13_N PF04088.13 CDJ45711.1 - 4.2 7.6 8.1 1.8 8.8 1.3 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region VIT1 PF01988.19 CDJ45711.1 - 5 6.9 12.0 9.9 6.0 12.0 1.5 1 1 0 1 1 1 0 VIT family STAC2_u1 PF16664.5 CDJ45711.1 - 5.1 7.6 11.8 3.3 8.2 3.0 2.2 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 ATAD4 PF15321.6 CDJ45711.1 - 6.1 8.3 10.4 14 7.1 1.9 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 TERB2 PF15101.6 CDJ45711.1 - 6.4 6.8 23.7 3.3 7.7 10.2 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Sox_N PF12444.8 CDJ45711.1 - 6.9 7.9 7.5 10 7.3 1.0 2.3 2 0 0 2 2 2 0 Sox developmental protein N terminal AIF_C PF14721.6 CDJ45711.1 - 7.1 7.0 11.5 11 6.4 3.0 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Stig1 PF04885.13 CDJ45711.1 - 7.3 7.1 10.0 18 5.8 3.1 2.1 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 Transglut_core3 PF13471.6 CDJ45711.1 - 7.7 6.4 14.8 3.3 7.7 8.9 2.3 2 0 0 2 2 2 0 Transglutaminase-like superfamily DUF2367 PF10164.9 CDJ45711.1 - 8 7.0 8.4 12 6.5 2.5 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) Rrn6 PF10214.9 CDJ45711.1 - 8 4.8 16.8 4.3 5.7 1.1 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Spore_coat_CotO PF14153.6 CDJ45711.1 - 8.4 6.3 26.0 3.6 7.5 6.8 2.1 2 0 0 2 2 2 0 Spore coat protein CotO TraV PF09676.10 CDJ45711.1 - 8.6 7.3 17.0 12 6.9 8.1 2.2 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Pinin_SDK_memA PF04696.13 CDJ45711.1 - 8.9 6.4 32.2 8.3 6.5 15.4 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Presenilin PF01080.17 CDJ45712.1 - 0.057 12.2 35.7 0.19 10.5 2.7 2.4 2 0 0 2 2 2 0 Presenilin Zip PF02535.22 CDJ45712.1 - 0.33 10.1 7.7 0.18 11.0 2.9 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter CDC45 PF02724.14 CDJ45712.1 - 1.1 7.4 19.9 4.6 5.4 0.2 2.1 2 0 0 2 2 2 0 CDC45-like protein BAF1_ABF1 PF04684.13 CDJ45712.1 - 2.9 6.9 25.4 11 5.0 0.2 2.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Tyrosinase PF00264.20 CDJ45712.1 - 7.5 6.8 21.2 0.24 11.7 10.6 2.5 3 0 0 3 3 3 0 Common central domain of tyrosinase Raffinose_syn PF05691.12 CDJ45713.1 - 0.00016 19.6 0.1 0.0049 14.7 0.0 2.2 2 0 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 DUF4746 PF15928.5 CDJ45714.1 - 0.19 11.1 7.6 0.18 11.2 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2722 PF10846.8 CDJ45714.1 - 0.29 10.0 25.2 0.3 10.0 25.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ45714.1 - 0.3 11.0 23.6 0.3 11.0 23.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTU2 PF10288.9 CDJ45714.1 - 0.42 10.9 8.2 0.47 10.7 8.2 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF5427 PF10310.9 CDJ45714.1 - 0.49 9.3 13.0 0.53 9.2 13.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SpoIIP PF07454.11 CDJ45714.1 - 0.5 9.8 8.2 0.46 9.9 8.2 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EIIBC-GUT_N PF03612.14 CDJ45714.1 - 0.52 10.0 4.9 0.56 9.9 4.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Spt20 PF12090.8 CDJ45714.1 - 0.58 9.7 30.7 0.59 9.7 30.7 1.0 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ45714.1 - 0.71 8.6 26.7 0.74 8.6 26.7 1.1 1 0 0 1 1 1 0 Androgen receptor Pex14_N PF04695.13 CDJ45714.1 - 1.3 9.7 14.4 1.3 9.6 14.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.11 CDJ45714.1 - 1.6 6.7 5.4 1.5 6.8 5.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TERB2 PF15101.6 CDJ45714.1 - 1.8 8.6 13.2 1.8 8.6 13.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ureide_permease PF07168.11 CDJ45714.1 - 1.9 7.1 2.7 2.1 7.0 2.7 1.0 1 0 0 1 1 1 0 Ureide permease DUF4407 PF14362.6 CDJ45714.1 - 2.7 7.3 12.9 2.6 7.3 12.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.17 CDJ45714.1 - 3.2 7.9 7.9 3.2 7.9 7.9 1.1 1 0 0 1 1 1 0 DDHD domain DUF4834 PF16118.5 CDJ45714.1 - 4.6 8.3 13.8 6.2 7.8 13.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Band_3_cyto PF07565.13 CDJ45714.1 - 4.8 6.9 8.5 4.9 6.9 8.5 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3464 PF11947.8 CDJ45714.1 - 5 6.9 9.4 5.3 6.8 9.4 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Suf PF05843.14 CDJ45714.1 - 5.4 6.9 12.9 5.2 7.0 12.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ45714.1 - 6 5.5 13.3 6.3 5.4 13.3 1.0 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 CDJ45714.1 - 6.2 6.5 7.2 6.2 6.5 7.2 1.1 1 0 0 1 1 1 0 Connexin PBP_sp32 PF07222.12 CDJ45714.1 - 6.3 6.2 15.7 6.4 6.2 15.7 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 AAA_28 PF13521.6 CDJ45714.1 - 9.1 6.5 8.1 8.5 6.6 7.3 1.3 1 1 0 1 1 1 0 AAA domain UPF0560 PF10577.9 CDJ45714.1 - 9.4 4.6 17.1 9.2 4.6 17.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Neur_chan_memb PF02932.16 CDJ45714.1 - 9.5 6.2 6.2 9 6.3 6.2 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EMC3_TMCO1 PF01956.16 CDJ45714.1 - 9.7 5.9 8.4 11 5.7 8.4 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Kri1_C PF12936.7 CDJ45715.1 - 2.4e-26 91.8 7.8 8.3e-26 90.0 7.8 1.8 1 1 0 1 1 1 1 KRI1-like family C-terminal RAP1 PF07218.11 CDJ45715.1 - 0.0014 17.1 7.7 0.0017 16.7 7.7 1.0 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) DUF3446 PF11928.8 CDJ45715.1 - 0.084 13.2 13.5 0.17 12.2 13.5 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain RR_TM4-6 PF06459.12 CDJ45715.1 - 0.085 12.7 6.2 0.11 12.4 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ45715.1 - 0.39 9.4 5.9 0.53 9.0 5.9 1.1 1 0 0 1 1 1 0 Presenilin KAP PF05804.12 CDJ45715.1 - 0.44 8.6 3.7 0.63 8.1 0.0 2.0 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) DUF508 PF04370.12 CDJ45715.1 - 4.6 7.0 8.4 8.6 6.1 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF4589 PF15252.6 CDJ45716.1 - 0.00061 19.9 0.4 0.0048 17.0 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4589) SR-25 PF10500.9 CDJ45716.1 - 1.9 8.0 6.7 3.3 7.2 6.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CDJ45716.1 - 8.3 6.9 15.5 0.65 10.5 7.9 2.5 2 1 0 2 2 2 0 Dehydrin DUF4647 PF15504.6 CDJ45717.1 - 0.39 9.8 20.7 0.49 9.4 20.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF966 PF06136.13 CDJ45717.1 - 2.3 7.8 30.7 2.9 7.5 30.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mitofilin PF09731.9 CDJ45717.1 - 3.6 6.3 35.4 4.9 5.9 35.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SLC12 PF03522.15 CDJ45717.1 - 4.8 6.1 16.8 6.4 5.7 16.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF5523 PF17661.1 CDJ45717.1 - 5.9 6.5 13.1 7.6 6.1 13.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Utp14 PF04615.13 CDJ45717.1 - 7 5.1 27.6 9.2 4.7 27.6 1.2 1 0 0 1 1 1 0 Utp14 protein AAA_13 PF13166.6 CDJ45717.1 - 9.2 4.8 15.2 11 4.5 15.2 1.2 1 0 0 1 1 1 0 AAA domain Mad3_BUB1_I PF08311.12 CDJ45718.1 - 0.0012 18.8 0.2 0.41 10.6 0.0 2.3 2 0 0 2 2 2 2 Mad3/BUB1 homology region 1 HAT PF02184.16 CDJ45718.1 - 0.0094 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 HAT (Half-A-TPR) repeat 14-3-3 PF00244.20 CDJ45718.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 14-3-3 protein ETRAMP PF09716.10 CDJ45719.1 - 6.4 6.9 0.0 6.4 6.9 0.0 4.7 6 2 0 6 6 6 0 Malarial early transcribed membrane protein (ETRAMP) Rad51 PF08423.11 CDJ45720.1 - 1.3e-12 47.6 1.3 3.8e-08 32.9 1.2 3.5 4 0 0 4 4 4 3 Rad51 RecA PF00154.21 CDJ45720.1 - 0.00041 19.9 0.0 0.00077 19.0 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CDJ45720.1 - 0.0089 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.6 CDJ45720.1 - 0.026 15.0 0.6 0.026 15.0 0.6 3.7 5 1 0 5 5 5 0 AAA domain EphA2_TM PF14575.6 CDJ45720.1 - 0.51 11.3 5.2 0.85 10.5 1.2 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Connexin PF00029.19 CDJ45720.1 - 1 9.1 6.9 2.7 7.7 6.9 1.7 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 CDJ45720.1 - 7.2 6.3 7.3 27 4.4 7.3 2.0 1 0 0 1 1 1 0 FAM176 family SARAF PF06682.12 CDJ45721.1 - 0.088 12.4 24.7 0.21 11.2 22.2 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis PAT1 PF09770.9 CDJ45721.1 - 0.18 10.1 36.3 0.29 9.4 36.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 CDJ45721.1 - 1.6 7.6 29.7 2.5 7.0 29.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.6 CDJ45721.1 - 2.2 6.6 6.7 2.9 6.2 6.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SR-25 PF10500.9 CDJ45722.1 - 0.0065 16.1 22.0 0.0065 16.1 22.0 4.9 2 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein DUF2076 PF09849.9 CDJ45722.1 - 1.7 8.6 53.8 1 9.4 25.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TFIIA PF03153.13 CDJ45723.1 - 1.8e-05 24.9 46.1 2.1e-05 24.7 46.1 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ45723.1 - 0.00026 21.3 32.9 0.0059 16.9 19.4 2.4 2 1 0 2 2 2 2 Anti-sigma-K factor rskA VIR_N PF15912.5 CDJ45723.1 - 1.7 8.2 13.4 2.9 7.4 13.4 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal Roughex PF06020.11 CDJ45723.1 - 6 5.9 15.9 12 4.9 15.9 1.7 1 0 0 1 1 1 0 Drosophila roughex protein DUF2722 PF10846.8 CDJ45724.1 - 0.003 16.6 29.8 0.0086 15.1 16.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) FAM76 PF16046.5 CDJ45724.1 - 0.16 11.3 19.5 0.048 13.0 5.3 2.3 2 0 0 2 2 2 0 FAM76 protein CNDH2_C PF16858.5 CDJ45724.1 - 0.57 10.0 17.0 0.072 13.0 7.7 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term eIF-3_zeta PF05091.12 CDJ45724.1 - 3.5 6.5 17.8 0.43 9.5 9.9 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HNOBA PF07701.14 CDJ45724.1 - 3.9 6.8 12.1 0.028 13.9 0.8 2.3 2 1 0 2 2 2 0 Heme NO binding associated Miga PF10265.9 CDJ45724.1 - 5.4 5.9 23.4 0.69 8.8 9.8 2.3 2 0 0 2 2 2 0 Mitoguardin GTP_EFTU PF00009.27 CDJ45726.1 - 1.4e-53 181.3 0.1 1.7e-53 181.1 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ45726.1 - 4.7e-05 23.4 0.0 0.0081 16.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 CDJ45726.1 - 0.13 12.6 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 CDJ45726.1 - 0.2 10.8 0.2 0.51 9.5 0.1 1.6 1 1 0 1 1 1 0 G-protein alpha subunit YcaO PF02624.16 CDJ45727.1 - 0.044 13.1 7.5 0.058 12.7 7.5 1.2 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding SprA-related PF12118.8 CDJ45727.1 - 0.23 10.5 46.6 0.27 10.3 46.6 1.1 1 0 0 1 1 1 0 SprA-related family PPP4R2 PF09184.11 CDJ45727.1 - 0.24 11.0 13.3 0.24 11.0 13.3 1.0 1 0 0 1 1 1 0 PPP4R2 SID-1_RNA_chan PF13965.6 CDJ45727.1 - 0.24 9.8 5.5 0.22 9.9 5.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIA PF03153.13 CDJ45727.1 - 0.69 9.8 52.5 0.82 9.6 52.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ADP_ribosyl_GH PF03747.14 CDJ45727.1 - 0.71 9.5 12.6 0.82 9.3 12.6 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Med15 PF09606.10 CDJ45727.1 - 0.9 8.2 42.6 1.1 7.9 42.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Velvet PF11754.8 CDJ45727.1 - 0.9 9.4 17.3 1.1 9.2 17.3 1.2 1 0 0 1 1 1 0 Velvet factor CCDC71L PF15374.6 CDJ45727.1 - 1.2 8.3 21.8 1.5 8.0 21.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L VIR_N PF15912.5 CDJ45727.1 - 1.7 8.2 13.4 1.8 8.1 13.4 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Neur_chan_memb PF02932.16 CDJ45727.1 - 2.3 8.2 15.2 3 7.8 15.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 CDJ45727.1 - 3.8 6.3 14.3 4.5 6.1 14.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SpoIIP PF07454.11 CDJ45727.1 - 4.3 6.7 21.1 5.8 6.3 21.1 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FAM60A PF15396.6 CDJ45727.1 - 5.1 7.0 15.6 5.9 6.8 15.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ45727.1 - 5.3 6.8 24.6 6.9 6.4 24.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ45727.1 - 5.3 5.9 27.0 5.7 5.8 27.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DcuA_DcuB PF03605.14 CDJ45727.1 - 6.4 5.6 11.5 8.2 5.2 11.5 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Pannexin_like PF12534.8 CDJ45727.1 - 6.5 5.7 15.6 7.1 5.6 15.6 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF1387 PF07139.11 CDJ45727.1 - 7.1 6.3 22.8 7.5 6.2 22.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Peptidase_S15 PF02129.18 CDJ45727.1 - 7.1 6.1 18.5 9.8 5.7 18.5 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Endostatin PF06482.11 CDJ45727.1 - 7.8 5.9 18.6 8.3 5.8 18.6 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF1980 PF09323.10 CDJ45727.1 - 8.3 6.3 14.3 11 5.9 14.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Raftlin PF15250.6 CDJ45727.1 - 9.1 4.9 20.3 10 4.7 20.3 1.1 1 0 0 1 1 1 0 Raftlin DUF913 PF06025.12 CDJ45727.1 - 9.1 5.1 16.4 11 4.9 16.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ribosomal_S9 PF00380.19 CDJ45728.1 - 5e-12 46.4 0.0 8.3e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S9/S16 Spore_II_R PF09551.10 CDJ45728.1 - 0.095 13.2 0.7 0.13 12.7 0.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) YpjP PF14005.6 CDJ45728.1 - 0.2 11.7 2.2 0.31 11.1 2.2 1.3 1 0 0 1 1 1 0 YpjP-like protein tRNA_bind_2 PF13725.6 CDJ45728.1 - 6.3 6.4 6.1 8.2 6.1 6.1 1.1 1 0 0 1 1 1 0 Possible tRNA binding domain zf_CopZ PF18423.1 CDJ45728.1 - 7.4 6.6 6.0 19 5.3 0.6 2.3 1 1 1 2 2 2 0 Zinc binding domain SAC3 PF12209.8 CDJ45728.1 - 9.5 6.5 7.0 8.2 6.7 1.5 2.2 1 1 1 2 2 2 0 Leucine permease transcriptional regulator helical domain DUF2722 PF10846.8 CDJ45729.1 - 0.00083 18.4 2.4 0.00083 18.4 2.4 5.0 4 1 0 4 4 3 1 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ45729.1 - 0.001 18.8 20.4 0.001 18.8 20.4 4.6 4 1 0 4 4 3 2 Nuclear RNA-splicing-associated protein SDA1 PF05285.12 CDJ45729.1 - 0.0054 16.2 15.0 0.0054 16.2 15.0 3.1 3 0 0 3 3 2 2 SDA1 SID-1_RNA_chan PF13965.6 CDJ45729.1 - 0.0068 14.9 7.0 0.038 12.4 0.9 2.6 3 0 0 3 3 3 2 dsRNA-gated channel SID-1 CSG2 PF16965.5 CDJ45729.1 - 0.032 13.2 14.1 0.37 9.7 5.7 2.5 2 0 0 2 2 2 0 Ceramide synthase regulator TPT PF03151.16 CDJ45729.1 - 0.064 12.6 0.1 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Triose-phosphate Transporter family Apt1 PF10351.9 CDJ45729.1 - 0.09 11.6 16.4 1.2 7.9 0.2 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain MFS_1_like PF12832.7 CDJ45729.1 - 0.14 11.0 0.0 3.6 6.3 0.0 2.4 2 1 0 2 2 2 0 MFS_1 like family 7tm_1 PF00001.21 CDJ45729.1 - 0.29 10.4 4.8 0.51 9.6 0.5 2.7 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) INSIG PF07281.12 CDJ45729.1 - 0.52 9.9 0.0 0.52 9.9 0.0 5.3 3 2 1 5 5 4 0 Insulin-induced protein (INSIG) Cellulose_synt PF03552.14 CDJ45729.1 - 0.74 8.2 5.4 1.9 6.9 5.4 1.6 1 0 0 1 1 1 0 Cellulose synthase GPCR_chapero_1 PF11904.8 CDJ45729.1 - 1.3 8.4 12.8 4.4 6.6 0.3 2.5 2 0 0 2 2 2 0 GPCR-chaperone SLC12 PF03522.15 CDJ45729.1 - 1.3 7.9 26.7 0.032 13.3 6.3 2.5 2 1 0 2 2 2 0 Solute carrier family 12 DUF3402 PF11882.8 CDJ45729.1 - 1.5 7.8 21.2 0.83 8.7 6.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) GWT1 PF06423.12 CDJ45729.1 - 2.4 8.3 9.3 0.89 9.7 0.1 3.3 2 1 1 3 3 3 0 GWT1 PA26 PF04636.13 CDJ45729.1 - 2.7 6.8 24.6 0.46 9.3 4.1 2.4 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Gaa1 PF04114.14 CDJ45729.1 - 3.2 6.7 13.8 0.21 10.6 2.0 2.9 2 1 0 2 2 2 0 Gaa1-like, GPI transamidase component Pkinase_fungal PF17667.1 CDJ45729.1 - 5 5.8 12.5 13 4.4 7.3 2.3 2 0 0 2 2 2 0 Fungal protein kinase SRPRB PF09439.10 CDJ45730.1 - 3e-12 46.3 0.0 6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CDJ45730.1 - 0.0001 21.9 0.0 0.00027 20.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CDJ45730.1 - 0.00036 20.0 0.0 0.00096 18.7 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family TFIIA PF03153.13 CDJ45730.1 - 0.0053 16.8 3.5 0.0053 16.8 3.5 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ45730.1 - 0.0076 15.9 9.0 0.017 14.8 9.0 1.5 1 0 0 1 1 1 1 Spt20 family RCC1 PF00415.18 CDJ45730.1 - 0.015 15.9 0.2 0.059 14.0 0.2 2.1 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat DUF2722 PF10846.8 CDJ45730.1 - 0.029 13.3 5.7 0.044 12.7 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RCC1_2 PF13540.6 CDJ45730.1 - 0.066 13.0 0.1 0.24 11.2 0.1 2.0 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat FeoB_N PF02421.18 CDJ45730.1 - 0.19 11.2 0.0 0.48 9.9 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF547 PF04784.14 CDJ45730.1 - 0.28 11.2 2.2 1.2 9.2 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function, DUF547 FAM150 PF15129.6 CDJ45730.1 - 1.7 8.8 5.3 4 7.6 3.7 2.3 2 0 0 2 2 2 0 FAM150 family Connexin PF00029.19 CDJ45731.1 - 9.5 5.9 9.3 20 4.8 9.3 1.5 1 0 0 1 1 1 0 Connexin Dynamin_N PF00350.23 CDJ45733.1 - 1.4e-14 54.5 0.0 1e-13 51.7 0.0 2.0 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 CDJ45733.1 - 9.2e-14 51.0 0.5 1.7e-13 50.2 0.5 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 CDJ45733.1 - 3.4e-07 30.4 0.0 6.6e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ45733.1 - 7.1e-06 25.7 0.0 0.0022 17.6 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF5600 PF18150.1 CDJ45733.1 - 0.0001 22.8 1.8 0.00034 21.2 0.8 2.2 3 0 0 3 3 2 1 Domain of unknown function (DUF5600) Roc PF08477.13 CDJ45733.1 - 0.00012 22.3 0.0 0.53 10.5 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CDJ45733.1 - 0.00059 19.8 0.0 0.15 12.0 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA_28 PF13521.6 CDJ45733.1 - 0.01 16.1 0.0 0.031 14.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CDJ45733.1 - 0.014 15.2 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 CDJ45733.1 - 0.026 13.9 0.0 0.062 12.7 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Septin PF00735.18 CDJ45733.1 - 0.067 12.5 0.0 0.42 9.9 0.0 1.9 2 0 0 2 2 2 0 Septin cobW PF02492.19 CDJ45733.1 - 0.083 12.5 0.0 11 5.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CDJ45733.1 - 0.12 12.7 0.1 0.47 10.8 0.0 2.0 3 0 0 3 3 3 0 AAA ATPase domain Ras PF00071.22 CDJ45733.1 - 0.15 11.7 0.0 14 5.3 0.0 2.2 2 0 0 2 2 2 0 Ras family Exonuc_VII_L PF02601.15 CDJ45734.1 - 6e-05 22.8 37.2 7.8e-05 22.4 37.2 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit Spc7 PF08317.11 CDJ45734.1 - 0.01 14.8 43.2 0.014 14.3 43.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ERM PF00769.19 CDJ45734.1 - 0.018 14.9 45.5 0.022 14.6 45.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FapA PF03961.13 CDJ45734.1 - 0.028 13.1 27.1 0.034 12.8 27.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3552 PF12072.8 CDJ45734.1 - 0.039 13.4 54.4 0.085 12.3 37.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) V_ATPase_I PF01496.19 CDJ45734.1 - 0.067 11.1 29.2 0.071 11.0 29.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 CDJ45734.1 - 0.077 13.5 53.2 0.12 12.9 53.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region PDDEXK_6 PF04720.12 CDJ45734.1 - 0.1 12.5 15.9 0.15 12.0 15.9 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function DUF3450 PF11932.8 CDJ45734.1 - 0.45 9.8 62.3 0.7 9.1 62.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fmp27_WPPW PF10359.9 CDJ45734.1 - 0.52 9.1 30.4 0.58 8.9 30.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain SLC12 PF03522.15 CDJ45734.1 - 1.1 8.2 25.9 1.2 8.0 25.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ45734.1 - 1.3 7.7 27.7 1.3 7.7 27.7 1.1 1 0 0 1 1 1 0 Presenilin Atg14 PF10186.9 CDJ45734.1 - 1.4 7.9 42.5 1.8 7.5 42.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SKA1 PF07160.12 CDJ45734.1 - 1.8 8.4 30.2 2.4 7.9 30.2 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 PIN_8 PF18476.1 CDJ45734.1 - 2.2 8.1 19.1 2.9 7.7 19.1 1.2 1 0 0 1 1 1 0 PIN like domain Macoilin PF09726.9 CDJ45734.1 - 2.3 6.7 36.8 2.9 6.4 36.8 1.0 1 0 0 1 1 1 0 Macoilin family DDHD PF02862.17 CDJ45734.1 - 2.3 8.3 22.0 2.6 8.1 22.0 1.1 1 0 0 1 1 1 0 DDHD domain GAS PF13851.6 CDJ45734.1 - 2.5 7.4 50.0 3.2 7.0 50.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 CDJ45734.1 - 2.9 6.4 24.7 4.2 5.9 24.7 1.2 1 0 0 1 1 1 0 AAA domain Vac7 PF12751.7 CDJ45734.1 - 3.5 7.0 11.2 3.8 6.8 11.2 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 GREB1 PF15782.5 CDJ45734.1 - 3.9 4.5 27.3 4.2 4.4 27.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Allexi_40kDa PF05549.11 CDJ45734.1 - 6.8 6.1 19.8 10 5.5 19.8 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Tyrosinase PF00264.20 CDJ45734.1 - 7.9 6.7 15.7 11 6.3 15.7 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase IFT57 PF10498.9 CDJ45734.1 - 8.4 5.2 44.2 12 4.7 44.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PAT1 PF09770.9 CDJ45734.1 - 10 4.3 49.8 10 4.2 49.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_S6e PF01092.19 CDJ45735.1 - 9.6e-15 54.7 0.1 9.6e-15 54.7 0.1 2.2 2 1 1 3 3 3 1 Ribosomal protein S6e Raftlin PF15250.6 CDJ45735.1 - 0.0051 15.6 7.8 0.0058 15.4 7.8 1.2 1 0 0 1 1 1 1 Raftlin PAT1 PF09770.9 CDJ45735.1 - 0.021 13.2 24.5 0.024 12.9 24.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CENP-F_C_Rb_bdg PF10490.9 CDJ45735.1 - 0.07 12.6 0.2 6.1 6.3 0.1 2.4 2 0 0 2 2 2 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Zip PF02535.22 CDJ45735.1 - 0.11 11.7 1.4 0.1 11.8 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Gti1_Pac2 PF09729.9 CDJ45735.1 - 0.14 12.2 9.8 0.33 11.0 9.8 1.7 1 0 0 1 1 1 0 Gti1/Pac2 family CDC45 PF02724.14 CDJ45735.1 - 0.16 10.2 9.6 0.22 9.8 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ45735.1 - 0.25 10.1 19.9 0.35 9.6 19.9 1.2 1 0 0 1 1 1 0 Presenilin Otopetrin PF03189.13 CDJ45735.1 - 0.38 9.5 1.5 0.41 9.4 1.5 1.2 1 0 0 1 1 1 0 Otopetrin MAT1 PF06391.13 CDJ45735.1 - 0.52 10.1 26.6 0.23 11.3 24.0 1.6 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 MAM1 PF10434.9 CDJ45735.1 - 1.2 8.6 20.5 2 8.0 20.5 1.3 1 0 0 1 1 1 0 Monopolin complex protein MAM1 Paf1 PF03985.13 CDJ45735.1 - 2.6 6.9 22.5 4.3 6.2 22.5 1.3 1 0 0 1 1 1 0 Paf1 Ndc1_Nup PF09531.10 CDJ45735.1 - 3.1 6.4 16.7 3.3 6.3 16.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_60s PF00428.19 CDJ45735.1 - 3.3 8.3 11.4 0.54 10.9 5.4 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein GREB1 PF15782.5 CDJ45735.1 - 3.4 4.6 15.5 4.2 4.4 15.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Endostatin PF06482.11 CDJ45735.1 - 5.2 6.4 18.6 8.3 5.8 18.6 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PA26 PF04636.13 CDJ45735.1 - 7.5 5.4 15.5 10 4.9 15.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Lin-8 PF03353.15 CDJ45735.1 - 8 5.9 24.7 12 5.4 24.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Neur_chan_memb PF02932.16 CDJ45735.1 - 8.1 6.4 16.3 14 5.6 16.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sporozoite_P67 PF05642.11 CDJ45737.1 - 3.2 5.7 26.1 7.8 4.4 26.1 1.5 1 1 0 1 1 1 0 Sporozoite P67 surface antigen RskA PF10099.9 CDJ45738.1 - 3.7e-06 27.4 9.8 4.9e-06 27.0 9.8 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TPR_14 PF13428.6 CDJ45738.1 - 1e-05 25.9 6.8 0.00036 21.1 0.0 3.3 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ45738.1 - 0.00011 22.7 0.2 0.00011 22.7 0.2 3.3 2 1 2 4 4 2 1 Tetratricopeptide repeat TFIIA PF03153.13 CDJ45738.1 - 0.0018 18.4 9.7 0.0018 18.4 9.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3682 PF12446.8 CDJ45738.1 - 0.012 16.1 11.4 0.02 15.4 11.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Spt20 PF12090.8 CDJ45738.1 - 0.022 14.4 14.6 0.03 13.9 14.6 1.2 1 0 0 1 1 1 0 Spt20 family TPR_7 PF13176.6 CDJ45738.1 - 0.023 14.7 0.1 2.1 8.5 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat RAB3GAP2_N PF14655.6 CDJ45738.1 - 0.04 13.2 2.5 0.05 12.9 2.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Rpp20 PF12328.8 CDJ45738.1 - 0.071 13.1 2.0 0.1 12.6 2.0 1.3 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P TPR_2 PF07719.17 CDJ45738.1 - 0.15 12.2 0.0 0.51 10.6 0.0 3.6 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF4179 PF13786.6 CDJ45738.1 - 0.21 12.1 1.5 0.32 11.5 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) G0-G1_switch_2 PF15103.6 CDJ45738.1 - 0.28 11.6 3.5 8.7 6.8 2.3 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 TPR_17 PF13431.6 CDJ45738.1 - 0.35 11.4 0.0 0.35 11.4 0.0 3.0 2 1 0 2 2 1 0 Tetratricopeptide repeat R_equi_Vir PF05526.11 CDJ45738.1 - 1.4 8.7 5.4 2 8.3 5.4 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF2722 PF10846.8 CDJ45738.1 - 2.5 7.0 16.1 3.4 6.5 16.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Roughex PF06020.11 CDJ45738.1 - 3.3 6.7 7.5 3.8 6.5 7.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SR-25 PF10500.9 CDJ45739.1 - 1.3 8.6 54.3 0.093 12.3 22.4 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.9 CDJ45739.1 - 8.1 4.6 67.1 9.8 4.3 67.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IMUP PF15761.5 CDJ45740.1 - 0.35 11.6 33.1 0.095 13.4 14.9 2.2 1 1 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ45740.1 - 0.56 9.8 40.7 0.043 13.4 27.1 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein PA26 PF04636.13 CDJ45740.1 - 0.88 8.4 13.9 0.99 8.3 13.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Dsh_C PF12316.8 CDJ45740.1 - 1.4 9.2 31.9 1.5 9.2 31.9 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CCSAP PF15748.5 CDJ45740.1 - 3.4 7.8 29.5 4.1 7.5 29.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated HemX PF04375.14 CDJ45740.1 - 7.4 5.7 27.1 8.3 5.6 27.1 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase VIT1 PF01988.19 CDJ45740.1 - 8.2 6.2 10.3 9.8 6.0 10.3 1.2 1 0 0 1 1 1 0 VIT family DUF4407 PF14362.6 CDJ45740.1 - 10 5.4 15.5 10 5.3 15.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SMC_N PF02463.19 CDJ45741.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ45741.1 - 0.00094 19.1 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDJ45741.1 - 0.0015 18.3 0.1 0.0029 17.4 0.0 1.4 2 0 0 2 2 2 1 AAA ATPase domain DUF3539 PF12058.8 CDJ45741.1 - 0.24 11.6 2.7 0.62 10.3 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3539) Actin PF00022.19 CDJ45742.1 - 0.00052 18.8 0.0 0.00052 18.8 0.0 2.2 1 1 0 2 2 2 1 Actin DUF2828 PF11443.8 CDJ45742.1 - 0.001 17.3 11.1 0.0012 17.1 11.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ45742.1 - 0.0015 17.4 22.0 0.0017 17.2 22.0 1.1 1 0 0 1 1 1 1 Presenilin Nop53 PF07767.11 CDJ45742.1 - 0.0027 17.2 23.9 0.0032 16.9 23.9 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Gti1_Pac2 PF09729.9 CDJ45742.1 - 0.0039 17.3 12.4 0.0059 16.7 12.4 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family RR_TM4-6 PF06459.12 CDJ45742.1 - 0.0043 16.9 18.3 0.006 16.4 18.3 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 TERB2 PF15101.6 CDJ45742.1 - 0.0058 16.7 6.2 0.0058 16.7 6.2 2.0 2 0 0 2 2 2 1 Telomere-associated protein TERB2 Trp_oprn_chp PF09534.10 CDJ45742.1 - 0.014 15.2 0.4 0.024 14.4 0.4 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) D123 PF07065.14 CDJ45742.1 - 0.034 13.3 15.8 0.17 11.0 2.2 2.0 2 0 0 2 2 2 0 D123 DUF3807 PF12720.7 CDJ45742.1 - 0.037 14.3 25.9 0.081 13.2 6.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) SART-1 PF03343.13 CDJ45742.1 - 0.049 12.2 20.8 0.062 11.8 20.8 1.1 1 0 0 1 1 1 0 SART-1 family Afi1 PF07792.12 CDJ45742.1 - 0.053 14.0 1.4 0.053 14.0 1.4 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CPSF100_C PF13299.6 CDJ45742.1 - 0.077 13.2 18.3 0.14 12.3 2.4 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Spt20 PF12090.8 CDJ45742.1 - 0.085 12.4 69.1 0.096 12.3 25.5 2.0 2 0 0 2 2 2 0 Spt20 family SpoIIP PF07454.11 CDJ45742.1 - 0.094 12.2 24.9 0.35 10.3 7.1 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TCP PF03634.13 CDJ45742.1 - 0.11 13.0 18.5 0.79 10.3 4.0 2.1 2 0 0 2 2 2 0 TCP family transcription factor AIF_C PF14721.6 CDJ45742.1 - 0.11 12.8 17.4 0.18 12.2 2.0 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MDM10 PF12519.8 CDJ45742.1 - 0.24 10.2 15.4 0.32 9.8 15.4 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 TFB6 PF17110.5 CDJ45742.1 - 0.24 11.1 15.0 0.42 10.3 2.5 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF4045 PF13254.6 CDJ45742.1 - 0.25 11.0 17.3 0.33 10.5 17.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DDHD PF02862.17 CDJ45742.1 - 0.26 11.4 21.6 0.15 12.2 3.8 2.0 2 0 0 2 2 2 0 DDHD domain DUF3899 PF13038.6 CDJ45742.1 - 0.4 11.2 0.7 2.9 8.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Pex14_N PF04695.13 CDJ45742.1 - 0.44 11.2 38.3 0.49 11.0 10.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ45742.1 - 0.45 10.5 58.7 0.14 12.2 20.0 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CBP_BcsG PF11658.8 CDJ45742.1 - 0.46 8.8 14.5 0.22 9.9 1.3 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG CAF1 PF04857.20 CDJ45742.1 - 0.46 9.6 11.5 0.63 9.2 11.5 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease U1snRNP70_N PF12220.8 CDJ45742.1 - 0.56 10.9 22.4 1.8 9.3 7.6 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ALMT PF11744.8 CDJ45742.1 - 0.58 8.9 14.3 0.72 8.6 14.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PRP1_N PF06424.12 CDJ45742.1 - 0.64 10.4 20.6 0.59 10.5 4.2 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal EFTUD2 PF16004.5 CDJ45742.1 - 0.67 10.6 25.4 0.14 12.8 4.0 2.1 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF4518 PF15008.6 CDJ45742.1 - 0.72 9.0 23.9 0.87 8.7 6.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) EPL1 PF10513.9 CDJ45742.1 - 0.87 10.0 27.1 0.75 10.2 6.3 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Senescence_reg PF04520.13 CDJ45742.1 - 0.92 10.3 14.2 1.3 9.9 14.2 1.3 1 0 0 1 1 1 0 Senescence regulator EIIBC-GUT_N PF03612.14 CDJ45742.1 - 0.96 9.2 23.9 0.55 10.0 5.3 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus XRN_M PF17846.1 CDJ45742.1 - 1.1 8.1 15.3 1.3 7.9 15.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain PRC2_HTH_1 PF18118.1 CDJ45742.1 - 1.2 10.0 17.3 1.7 9.5 3.6 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain BSP_II PF05432.11 CDJ45742.1 - 1.2 8.7 16.4 4.1 7.0 16.4 1.7 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) RPN2_C PF18004.1 CDJ45742.1 - 1.3 8.9 21.8 0.64 9.9 6.1 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain UPF0239 PF06783.11 CDJ45742.1 - 1.4 9.1 16.2 0.57 10.4 3.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) NPR1_interact PF15699.5 CDJ45742.1 - 1.6 9.4 27.5 3.5 8.3 8.7 2.1 2 0 0 2 2 2 0 NPR1 interacting Tim54 PF11711.8 CDJ45742.1 - 1.6 7.4 22.3 0.29 9.9 4.4 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF3306 PF11748.8 CDJ45742.1 - 1.6 9.6 24.2 1.7 9.6 6.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) CrgA PF06781.12 CDJ45742.1 - 1.7 8.7 8.4 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Cell division protein CrgA RPA43_OB PF17875.1 CDJ45742.1 - 1.8 9.2 19.5 1.1 10.0 4.0 2.1 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF4551 PF15087.6 CDJ45742.1 - 2 7.2 20.8 2.3 6.9 20.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4834 PF16118.5 CDJ45742.1 - 2.7 9.0 35.1 0.48 11.4 10.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CobT PF06213.12 CDJ45742.1 - 2.9 7.2 40.7 0.59 9.5 13.6 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT PSCyt3 PF07627.11 CDJ45742.1 - 3 8.2 20.1 0.092 13.0 5.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) AUX_IAA PF02309.16 CDJ45742.1 - 3.2 7.5 15.7 4.2 7.1 15.7 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF3464 PF11947.8 CDJ45742.1 - 3.8 7.3 28.3 1.6 8.5 8.2 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Thg1C PF14413.6 CDJ45742.1 - 4.3 7.5 21.3 0.36 11.0 2.8 2.1 2 0 0 2 2 2 0 Thg1 C terminal domain PTPRCAP PF15713.5 CDJ45742.1 - 4.4 7.6 28.5 0.21 11.9 5.8 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RuvC_III PF18541.1 CDJ45742.1 - 4.9 7.1 18.7 6.1 6.8 4.8 2.1 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 ORC_WH_C PF18137.1 CDJ45742.1 - 4.9 7.2 23.7 1.9 8.5 6.5 2.1 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Sox_N PF12444.8 CDJ45742.1 - 5.1 8.3 14.8 4.9 8.4 4.6 2.2 2 0 0 2 2 2 0 Sox developmental protein N terminal Peroxin-3 PF04882.12 CDJ45742.1 - 6.3 5.7 22.5 8.1 5.3 22.5 1.2 1 0 0 1 1 1 0 Peroxin-3 eIF-3_zeta PF05091.12 CDJ45742.1 - 6.5 5.6 32.6 1.6 7.6 11.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF5327 PF17261.2 CDJ45742.1 - 6.6 7.6 38.8 11 6.9 15.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Ndc1_Nup PF09531.10 CDJ45742.1 - 6.6 5.3 20.4 8.8 4.9 20.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RLL PF10036.9 CDJ45742.1 - 7.1 6.4 27.9 1.4 8.7 6.9 2.1 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein GNAT_acetyltr_2 PF13718.6 CDJ45742.1 - 7.5 5.9 19.4 0.49 9.8 2.1 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase 2 eIF_4EBP PF05456.11 CDJ45742.1 - 8 6.4 25.8 8.5 6.4 7.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) FmiP_Thoc5 PF09766.9 CDJ45742.1 - 8.1 5.6 32.7 1.7 7.8 10.3 2.0 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Jak1_Phl PF17887.1 CDJ45742.1 - 8.4 6.4 21.4 1.2 9.1 4.2 2.1 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain HNOBA PF07701.14 CDJ45742.1 - 9.5 5.6 20.6 6 6.2 6.0 2.1 2 0 0 2 2 2 0 Heme NO binding associated AAR2 PF05282.11 CDJ45742.1 - 9.6 5.5 18.2 2.7 7.3 2.3 2.0 2 0 0 2 2 2 0 AAR2 protein Actin PF00022.19 CDJ45743.1 - 2.5e-24 85.6 0.5 4.4e-22 78.3 0.0 2.6 2 1 0 2 2 2 1 Actin RskA PF10099.9 CDJ45743.1 - 0.013 15.8 5.7 0.013 15.8 5.7 4.5 3 1 1 4 4 4 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ45743.1 - 3.4 7.5 45.6 0.041 13.9 2.1 2.6 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 CDJ45744.1 - 1.6 7.8 27.5 2.2 7.4 27.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 CDJ45746.1 - 0.0001 22.4 30.8 0.004 17.1 2.8 2.3 2 0 0 2 2 2 2 SPX domain 4HBT PF03061.22 CDJ45746.1 - 0.00084 19.6 0.0 0.00084 19.6 0.0 2.2 2 0 0 2 2 1 1 Thioesterase superfamily Apt1 PF10351.9 CDJ45746.1 - 0.028 13.3 34.1 0.014 14.3 2.7 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Sporozoite_P67 PF05642.11 CDJ45746.1 - 0.032 12.3 31.1 0.058 11.5 31.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BAF1_ABF1 PF04684.13 CDJ45746.1 - 0.044 12.9 35.8 0.029 13.5 12.5 2.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor BUD22 PF09073.10 CDJ45746.1 - 0.046 13.1 31.3 0.13 11.6 6.2 2.3 2 0 0 2 2 2 0 BUD22 Pkinase_fungal PF17667.1 CDJ45746.1 - 0.28 9.9 8.3 1 8.0 3.5 2.2 2 0 0 2 2 2 0 Fungal protein kinase Zip PF02535.22 CDJ45746.1 - 0.99 8.6 13.2 2.7 7.1 7.9 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Mem_trans PF03547.18 CDJ45746.1 - 1.8 6.8 19.0 0.78 8.1 0.0 2.1 2 0 0 2 2 2 0 Membrane transport protein DUF966 PF06136.13 CDJ45746.1 - 5 6.7 34.0 1.5 8.5 6.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Miga PF10265.9 CDJ45746.1 - 5.1 5.9 33.8 0.17 10.9 16.9 2.2 2 0 0 2 2 2 0 Mitoguardin Macoilin PF09726.9 CDJ45746.1 - 5.5 5.4 55.1 1.3 7.5 26.3 2.4 2 1 0 2 2 2 0 Macoilin family MACPF PF01823.19 CDJ45746.1 - 9.6 6.2 21.9 1.4 8.9 12.5 2.3 2 0 0 2 2 2 0 MAC/Perforin domain DUF4203 PF13886.6 CDJ45747.1 - 0.078 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Trp_oprn_chp PF09534.10 CDJ45748.1 - 0.0035 17.2 11.5 0.0041 16.9 11.5 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4148 PF13663.6 CDJ45748.1 - 0.0051 17.0 13.9 0.012 15.8 2.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4148) DUF2722 PF10846.8 CDJ45748.1 - 0.039 12.9 7.2 0.041 12.8 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ45748.1 - 0.04 13.5 11.5 0.042 13.4 11.5 1.1 1 0 0 1 1 1 0 Spt20 family ETRAMP PF09716.10 CDJ45748.1 - 0.082 13.0 0.1 0.082 13.0 0.1 1.9 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) MAPEG PF01124.18 CDJ45748.1 - 0.098 12.6 4.8 0.12 12.2 4.8 1.1 1 0 0 1 1 1 0 MAPEG family DUF4366 PF14283.6 CDJ45748.1 - 0.12 12.4 3.9 0.15 12.1 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SUIM_assoc PF16619.5 CDJ45748.1 - 0.14 12.2 12.5 0.26 11.4 12.5 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4820 PF16091.5 CDJ45748.1 - 0.33 10.3 4.3 0.36 10.1 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4834 PF16118.5 CDJ45748.1 - 0.63 11.0 4.0 0.74 10.8 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) baeRF_family10 PF18854.1 CDJ45748.1 - 0.63 10.3 7.9 1 9.6 7.9 1.4 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 RAB3GAP2_N PF14655.6 CDJ45748.1 - 0.79 8.9 4.4 0.89 8.7 4.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CDK2AP PF09806.9 CDJ45748.1 - 0.93 9.5 15.7 1.1 9.3 15.7 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3391 PF11871.8 CDJ45748.1 - 1.3 9.6 7.5 1.5 9.3 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) TFIIA PF03153.13 CDJ45748.1 - 1.4 8.8 15.8 1.4 8.8 15.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ45748.1 - 2.2 7.3 7.9 2.5 7.0 7.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ45748.1 - 2.3 6.9 5.5 2.4 6.8 5.5 1.0 1 0 0 1 1 1 0 Presenilin TraV PF09676.10 CDJ45748.1 - 3.2 8.7 12.0 3.6 8.6 12.0 1.0 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) ASFV_J13L PF05568.11 CDJ45748.1 - 5.7 6.6 12.7 7.3 6.3 12.7 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Kei1 PF08552.11 CDJ45748.1 - 5.7 6.8 7.3 6.6 6.6 7.3 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RskA PF10099.9 CDJ45748.1 - 8.7 6.6 32.7 1.3 9.3 17.2 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA eIF3_subunit PF08597.10 CDJ45748.1 - 9.5 6.1 13.7 12 5.7 13.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Roughex PF06020.11 CDJ45748.1 - 9.7 5.2 9.2 10 5.1 9.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Adaptin_N PF01602.20 CDJ45749.1 - 4.6e-33 114.6 16.5 1.4e-22 80.0 11.8 4.0 3 1 0 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 CDJ45749.1 - 0.00026 21.1 3.8 0.00074 19.6 0.2 3.0 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CDJ45749.1 - 0.14 12.2 10.1 1.7 8.8 0.8 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat dCMP_cyt_deam_2 PF08211.12 CDJ45750.1 - 0.0029 17.8 16.8 0.031 14.5 16.8 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SLC12 PF03522.15 CDJ45750.1 - 0.047 12.7 25.6 0.048 12.7 25.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 CDJ45750.1 - 0.39 10.7 22.4 0.42 10.6 22.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FRQ PF09421.10 CDJ45750.1 - 0.43 8.5 14.5 0.48 8.4 14.5 1.0 1 0 0 1 1 1 0 Frequency clock protein BAF1_ABF1 PF04684.13 CDJ45750.1 - 0.57 9.2 26.0 0.68 8.9 26.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ45750.1 - 0.85 8.3 34.1 0.88 8.3 34.1 1.0 1 0 0 1 1 1 0 Presenilin TAF4 PF05236.14 CDJ45750.1 - 1.2 8.8 26.6 1.8 8.3 26.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Hydin_ADK PF17213.3 CDJ45750.1 - 1.4 9.1 22.5 1.5 9.1 22.5 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MCM_bind PF09739.9 CDJ45750.1 - 2.4 6.5 25.8 2.8 6.3 25.8 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Sec62 PF03839.16 CDJ45750.1 - 2.5 7.6 25.1 2.6 7.5 25.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 NARP1 PF12569.8 CDJ45750.1 - 4.3 6.1 25.1 5.2 5.9 25.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Merozoite_SPAM PF07133.11 CDJ45750.1 - 4.5 7.2 27.0 7.3 6.5 27.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Gti1_Pac2 PF09729.9 CDJ45750.1 - 4.7 7.3 23.3 7.3 6.6 23.3 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Pkinase_fungal PF17667.1 CDJ45750.1 - 4.8 5.9 13.3 5.4 5.7 13.3 1.1 1 0 0 1 1 1 0 Fungal protein kinase ASC PF00858.24 CDJ45750.1 - 5.2 5.9 15.3 6.1 5.7 15.3 1.0 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel RR_TM4-6 PF06459.12 CDJ45750.1 - 5.5 6.7 35.6 6.1 6.6 35.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ45750.1 - 5.7 5.1 29.1 6.1 5.0 29.1 1.0 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.12 CDJ45750.1 - 5.9 7.1 25.9 6.1 7.0 25.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4746 PF15928.5 CDJ45750.1 - 6.3 6.1 24.8 9.8 5.5 24.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3292 PF11696.8 CDJ45750.1 - 8.6 4.6 20.6 8.8 4.6 20.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF4045 PF13254.6 CDJ45750.1 - 9.8 5.7 28.6 11 5.6 28.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3626 PF12294.8 CDJ45752.1 - 5.6e-08 32.2 0.1 0.00059 19.0 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3626) Pkinase PF00069.25 CDJ45753.1 - 2.9e-25 89.1 0.0 3.6e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ45753.1 - 4.5e-16 58.9 0.0 5.7e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ45753.1 - 2e-07 30.1 0.0 2.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Activator_LAG-3 PF11498.8 CDJ45754.1 - 0.025 13.6 19.7 0.026 13.5 19.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pex14_N PF04695.13 CDJ45754.1 - 0.035 14.8 9.7 0.045 14.4 9.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.19 CDJ45754.1 - 0.048 11.6 0.8 0.051 11.5 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2368 PF10166.9 CDJ45754.1 - 0.056 13.1 10.1 0.08 12.6 10.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Spt20 PF12090.8 CDJ45754.1 - 0.097 12.3 14.3 0.1 12.2 14.3 1.1 1 0 0 1 1 1 0 Spt20 family Ribosomal_60s PF00428.19 CDJ45754.1 - 0.17 12.5 16.9 0.74 10.4 8.1 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2722 PF10846.8 CDJ45754.1 - 0.32 9.9 10.1 0.36 9.7 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ45754.1 - 0.42 10.6 18.9 0.44 10.5 18.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PhoD PF09423.10 CDJ45754.1 - 0.45 9.5 8.8 0.54 9.2 8.8 1.0 1 0 0 1 1 1 0 PhoD-like phosphatase DUF5345 PF17280.2 CDJ45754.1 - 1.3 9.0 15.8 4 7.5 9.9 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5345) CNDH2_C PF16858.5 CDJ45755.1 - 0.0014 18.6 9.1 0.0014 18.6 9.1 4.8 4 1 1 5 5 5 3 Condensin II complex subunit CAP-H2 or CNDH2, C-term Adaptin_binding PF10199.9 CDJ45755.1 - 0.003 18.2 0.7 0.003 18.2 0.7 5.8 4 2 1 5 5 5 1 Alpha and gamma adaptin binding protein p34 RskA PF10099.9 CDJ45756.1 - 0.59 10.4 7.5 1.6 9.0 7.5 1.8 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SAP PF02037.27 CDJ45757.1 - 0.00093 18.9 0.5 0.0015 18.2 0.5 1.2 1 0 0 1 1 1 1 SAP domain zf-C2HE PF16278.5 CDJ45757.1 - 0.008 16.6 0.7 0.017 15.6 0.7 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger ESM4 PF15952.5 CDJ45758.1 - 0.00038 20.9 6.8 0.00042 20.8 6.8 1.2 1 0 0 1 1 1 1 Enhancer of split M4 family Spt20 PF12090.8 CDJ45758.1 - 0.00044 20.0 17.8 0.00057 19.6 17.8 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ45758.1 - 0.0039 16.2 11.4 0.0056 15.7 11.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ45758.1 - 0.0092 16.0 32.7 0.012 15.6 32.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PPL5 PF18168.1 CDJ45758.1 - 0.023 14.0 0.3 0.035 13.4 0.3 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Orf78 PF06024.12 CDJ45758.1 - 0.023 15.0 0.6 0.052 13.9 0.6 1.6 1 0 0 1 1 1 0 Orf78 (ac78) PBP1_TM PF14812.6 CDJ45758.1 - 0.026 14.9 0.3 0.026 14.9 0.3 2.0 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ADP_ribosyl_GH PF03747.14 CDJ45758.1 - 0.034 13.9 7.4 0.04 13.6 7.4 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase EIF4E-T PF10477.9 CDJ45758.1 - 0.049 12.5 13.8 0.057 12.3 13.8 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Presenilin PF01080.17 CDJ45758.1 - 0.057 12.2 2.8 0.06 12.1 2.8 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ45758.1 - 0.057 11.3 2.5 0.06 11.3 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ45758.1 - 0.19 11.5 2.0 0.26 11.0 2.0 1.3 1 0 0 1 1 1 0 Connexin EMC3_TMCO1 PF01956.16 CDJ45758.1 - 0.19 11.4 1.9 0.27 10.9 1.9 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CSG2 PF16965.5 CDJ45758.1 - 0.33 9.9 1.9 0.43 9.5 1.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator RskA PF10099.9 CDJ45758.1 - 0.58 10.4 35.9 51 4.1 37.3 2.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF3464 PF11947.8 CDJ45758.1 - 0.62 9.8 3.3 1.2 8.9 3.3 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 LMBR1 PF04791.16 CDJ45758.1 - 0.75 8.6 1.6 0.87 8.4 1.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1501 PF07394.12 CDJ45758.1 - 0.79 8.7 11.9 0.94 8.5 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) MMR1 PF08505.10 CDJ45758.1 - 0.83 9.9 9.1 1 9.6 9.1 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF3984 PF13136.6 CDJ45758.1 - 0.9 8.9 9.3 0.66 9.3 7.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) CLN3 PF02487.17 CDJ45758.1 - 0.93 8.5 3.8 1.3 8.0 3.8 1.3 1 0 0 1 1 1 0 CLN3 protein ABC2_membrane_2 PF12679.7 CDJ45758.1 - 1.6 8.0 7.3 2.4 7.3 7.3 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein ARF7EP_C PF14949.6 CDJ45758.1 - 2.2 9.0 7.6 3.8 8.2 7.6 1.3 1 0 0 1 1 1 0 ARF7 effector protein C-terminus PAT1 PF09770.9 CDJ45758.1 - 2.3 6.4 19.8 2.7 6.1 19.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4834 PF16118.5 CDJ45758.1 - 2.8 9.0 10.3 20 6.2 10.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Peptidase_S15 PF02129.18 CDJ45758.1 - 3.6 7.1 11.8 5 6.6 11.8 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Histone_HNS PF00816.21 CDJ45758.1 - 7.5 7.5 16.1 1.7 9.5 9.3 2.4 2 0 0 2 2 2 0 H-NS histone family WRNPLPNID PF15017.6 CDJ45758.1 - 9.6 7.2 17.3 6.5 7.7 12.4 2.2 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Nop53 PF07767.11 CDJ45762.1 - 2.4e-20 73.3 28.8 3.3e-20 72.8 28.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF3446 PF11928.8 CDJ45762.1 - 0.31 11.4 7.8 0.19 12.0 2.6 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Coilin_N PF15862.5 CDJ45763.1 - 3.4e-05 23.7 0.3 3.4e-05 23.7 0.3 10.8 7 3 2 9 9 9 1 Coilin N-terminus NPR3 PF03666.13 CDJ45763.1 - 0.00012 21.0 5.9 0.00012 21.0 5.9 5.4 4 1 0 6 6 6 1 Nitrogen Permease regulator of amino acid transport activity 3 La PF05383.17 CDJ45763.1 - 0.0013 18.7 10.8 0.013 15.6 0.2 3.1 3 0 0 3 3 3 2 La domain UPF0564 PF10595.9 CDJ45763.1 - 0.0022 17.1 20.0 0.0022 17.1 20.0 5.5 5 1 1 6 6 6 2 Uncharacterised protein family UPF0564 Peptidase_C12 PF01088.21 CDJ45764.1 - 2e-06 27.7 0.0 2e-06 27.7 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase, family 1 TFIIA PF03153.13 CDJ45764.1 - 0.14 12.2 11.5 0.35 10.8 4.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ45764.1 - 4.6 5.8 18.4 11 4.6 18.4 1.7 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FHIPEP PF00771.20 CDJ45765.1 - 0.011 14.2 0.9 0.011 14.2 0.9 1.0 1 0 0 1 1 1 0 FHIPEP family PmbA_TldD PF01523.16 CDJ45765.1 - 0.049 13.5 8.4 0.057 13.3 8.4 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DUF5421 PF17458.2 CDJ45765.1 - 0.072 12.5 5.0 0.1 11.9 5.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) eIF_4EBP PF05456.11 CDJ45765.1 - 0.12 12.3 4.9 0.21 11.5 4.9 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Dicty_REP PF05086.12 CDJ45765.1 - 0.24 9.3 8.6 0.29 9.1 8.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein IHABP4_N PF16174.5 CDJ45765.1 - 0.3 11.7 9.5 0.42 11.2 9.5 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal TFIIA PF03153.13 CDJ45765.1 - 0.37 10.8 22.7 0.43 10.5 22.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ45765.1 - 0.65 9.9 10.8 0.77 9.7 10.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 CDJ45765.1 - 0.86 7.8 11.4 0.81 7.9 11.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RskA PF10099.9 CDJ45765.1 - 9.7 6.4 24.6 11 6.2 24.6 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF4685 PF15737.5 CDJ45766.1 - 0.041 14.3 5.1 0.1 13.0 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) E1-E2_ATPase PF00122.20 CDJ45767.1 - 1.6e-29 102.7 3.8 1.4e-15 57.3 1.8 3.5 4 0 0 4 4 2 2 E1-E2 ATPase HMA PF00403.26 CDJ45767.1 - 1.7e-21 76.4 1.4 4.8e-10 39.7 0.0 2.8 2 1 0 2 2 2 2 Heavy-metal-associated domain Hydrolase PF00702.26 CDJ45767.1 - 5.8e-05 23.5 17.2 0.011 16.1 0.1 4.0 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase SDA1 PF05285.12 CDJ45767.1 - 0.0041 16.6 5.8 0.0074 15.8 5.8 1.3 1 0 0 1 1 1 1 SDA1 DUF2828 PF11443.8 CDJ45767.1 - 0.0065 14.6 7.2 0.01 14.0 7.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Smg8_Smg9 PF10220.9 CDJ45767.1 - 0.032 12.5 7.4 0.049 12.0 7.4 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Serinc PF03348.15 CDJ45767.1 - 0.043 12.8 1.4 0.13 11.2 1.4 1.8 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.12 CDJ45767.1 - 0.051 13.4 11.3 0.12 12.2 11.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ45767.1 - 0.077 11.8 16.3 0.21 10.3 16.3 1.7 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ45767.1 - 0.12 12.5 9.4 1.7 8.7 11.6 1.8 2 0 0 2 2 1 0 Neurotransmitter-gated ion-channel transmembrane region MAT1 PF06391.13 CDJ45767.1 - 0.26 11.1 20.8 0.51 10.1 20.8 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 SARAF PF06682.12 CDJ45767.1 - 0.34 10.5 12.1 1.2 8.7 12.1 1.9 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1980 PF09323.10 CDJ45767.1 - 0.35 10.8 8.3 2.1 8.2 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4667 PF15700.5 CDJ45767.1 - 0.47 10.5 16.3 1.2 9.2 10.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) PIP5K PF01504.18 CDJ45767.1 - 0.57 9.3 8.4 0.99 8.6 8.4 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF2464 PF10240.9 CDJ45767.1 - 0.67 9.5 7.2 1.4 8.4 7.2 1.5 1 0 0 1 1 1 0 Multivesicular body subunit 12 CLN3 PF02487.17 CDJ45767.1 - 0.71 8.9 7.3 1.9 7.4 7.3 1.7 1 0 0 1 1 1 0 CLN3 protein Dpy19 PF10034.9 CDJ45767.1 - 0.78 7.9 2.3 5.9 5.0 0.8 2.1 2 0 0 2 2 2 0 Q-cell neuroblast polarisation XRN_M PF17846.1 CDJ45767.1 - 1.3 7.9 9.8 2 7.3 9.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain V_ATPase_I PF01496.19 CDJ45767.1 - 1.6 6.6 13.6 2.5 5.9 13.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 CDJ45767.1 - 1.7 7.6 14.5 2.8 6.8 14.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 CDJ45767.1 - 3.4 7.7 11.3 8.9 6.4 11.3 1.6 1 0 0 1 1 1 0 Gti1/Pac2 family FAM60A PF15396.6 CDJ45767.1 - 4.9 7.1 15.8 0.24 11.4 9.6 2.0 2 0 0 2 2 1 0 Protein Family FAM60A ALMT PF11744.8 CDJ45767.1 - 5.1 5.8 9.8 9 5.0 9.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Spt20 PF12090.8 CDJ45767.1 - 8.9 5.8 58.7 0.37 10.4 15.8 2.6 2 0 0 2 2 2 0 Spt20 family Mlo PF03094.15 CDJ45768.1 - 0.25 9.6 0.0 0.25 9.6 0.0 2.5 1 1 1 2 2 2 0 Mlo family Methyltransf_5 PF01795.19 CDJ45769.1 - 1.2e-29 103.8 1.6 6.1e-10 39.1 0.0 4.0 3 1 0 3 3 3 3 MraW methylase family Methyltransf_25 PF13649.6 CDJ45769.1 - 0.3 11.8 6.2 0.96 10.2 0.1 3.4 3 0 0 3 3 3 0 Methyltransferase domain AF-4 PF05110.13 CDJ45769.1 - 0.78 7.7 45.6 0.27 9.3 17.2 2.9 3 0 0 3 3 3 0 AF-4 proto-oncoprotein Peptidase_S66C PF17676.1 CDJ45769.1 - 3.7 8.1 7.0 2.1 8.9 0.8 3.0 3 0 0 3 3 3 0 LD-carboxypeptidase C-terminal domain AAA_23 PF13476.6 CDJ45769.1 - 7.2 7.1 26.6 1.4 9.3 6.0 3.2 3 0 0 3 3 3 0 AAA domain RskA PF10099.9 CDJ45771.1 - 0.012 15.9 5.6 0.015 15.6 5.6 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Trypan_PARP PF05887.11 CDJ45771.1 - 0.032 14.2 13.7 0.032 14.2 13.7 2.9 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) Shadoo PF14999.6 CDJ45771.1 - 0.049 13.7 7.2 0.075 13.1 7.2 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective MAJIN PF15077.6 CDJ45771.1 - 0.27 11.0 2.2 0.33 10.7 2.2 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein OMP_b-brl PF13505.6 CDJ45771.1 - 2.4 8.2 3.7 3 7.9 3.7 1.3 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain PulA_N1 PF17999.1 CDJ45771.1 - 2.9 8.7 15.9 14 6.5 7.6 2.3 1 1 1 2 2 2 0 Pullulanase N1-terminal domain GcrA PF07750.11 CDJ45771.1 - 4 7.8 9.4 4.9 7.6 4.4 2.2 1 1 1 2 2 2 0 GcrA cell cycle regulator Smg8_Smg9 PF10220.9 CDJ45771.1 - 5 5.3 9.0 5.8 5.1 9.0 1.0 1 0 0 1 1 1 0 Smg8_Smg9 DUF1062 PF06353.12 CDJ45771.1 - 5.1 7.9 9.1 10 6.9 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1062) AMP-binding_C_2 PF14535.6 CDJ45771.1 - 8.6 6.8 13.3 2.8 8.3 6.5 2.2 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain DUF3446 PF11928.8 CDJ45772.1 - 2.7 8.4 16.6 4.2 7.8 16.6 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain VWA_2 PF13519.6 CDJ45773.1 - 0.018 15.7 0.5 0.018 15.7 0.5 3.8 4 1 1 5 5 5 0 von Willebrand factor type A domain K_channel_TID PF07941.11 CDJ45775.1 - 0.032 14.7 1.1 0.032 14.7 1.1 13.1 9 2 3 12 12 12 0 Potassium channel Kv1.4 tandem inactivation domain ABC2_membrane_2 PF12679.7 CDJ45775.1 - 0.34 10.1 0.0 0.34 10.1 0.0 5.4 4 1 0 4 4 4 0 ABC-2 family transporter protein RskA PF10099.9 CDJ45778.1 - 0.0057 17.0 3.5 0.0057 17.0 3.5 11.5 2 2 8 10 10 10 3 Anti-sigma-K factor rskA DUF4813 PF16072.5 CDJ45779.1 - 5 6.7 16.9 9 5.9 16.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) FAM76 PF16046.5 CDJ45780.1 - 1.6 8.0 22.8 2 7.7 22.8 1.0 1 0 0 1 1 1 0 FAM76 protein WES_acyltransf PF03007.16 CDJ45780.1 - 2 8.1 13.4 2.4 7.8 13.4 1.1 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF5427 PF10310.9 CDJ45780.1 - 2.1 7.2 29.9 2.3 7.1 29.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) N6_N4_Mtase PF01555.18 CDJ45781.1 - 0.017 14.8 0.0 0.045 13.5 0.0 1.8 1 1 0 1 1 1 0 DNA methylase V_ATPase_I PF01496.19 CDJ45781.1 - 2.6 5.8 32.5 0.44 8.4 22.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Spt20 PF12090.8 CDJ45782.1 - 7.8e-05 22.4 11.2 7.8e-05 22.4 11.2 3.0 2 1 0 2 2 2 1 Spt20 family DUF2722 PF10846.8 CDJ45782.1 - 0.0017 17.4 11.7 0.0017 17.4 11.7 3.3 2 1 0 3 3 3 1 Protein of unknown function (DUF2722) Apt1 PF10351.9 CDJ45782.1 - 0.0025 16.7 24.5 0.077 11.8 2.1 2.2 2 0 0 2 2 2 2 Golgi-body localisation protein domain RED_N PF07808.13 CDJ45782.1 - 0.0032 17.1 2.6 0.0032 17.1 2.6 2.7 2 1 0 2 2 2 1 RED-like protein N-terminal region SPX PF03105.19 CDJ45782.1 - 0.052 13.5 37.0 0.32 10.9 22.9 2.3 2 1 0 2 2 2 0 SPX domain Lin-8 PF03353.15 CDJ45782.1 - 0.091 12.3 25.5 0.013 15.1 3.2 2.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Plasmodium_Vir PF05795.11 CDJ45782.1 - 3.3 7.0 20.1 4.4 6.6 0.7 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF3984 PF13136.6 CDJ45784.1 - 0.064 12.7 27.1 0.087 12.2 27.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) MAP7 PF05672.11 CDJ45784.1 - 0.19 11.4 36.7 0.23 11.1 36.7 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Macoilin PF09726.9 CDJ45784.1 - 0.22 10.0 23.0 0.31 9.6 23.0 1.3 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CDJ45784.1 - 0.27 10.0 33.1 0.31 9.8 33.1 1.1 1 0 0 1 1 1 0 Presenilin IHABP4_N PF16174.5 CDJ45784.1 - 0.29 11.7 28.8 0.4 11.3 28.8 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal CCSAP PF15748.5 CDJ45784.1 - 1 9.5 32.4 1.3 9.2 32.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Zip PF02535.22 CDJ45784.1 - 1.5 8.0 27.1 1.8 7.7 27.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PNISR PF15996.5 CDJ45784.1 - 1.7 8.8 28.3 2.4 8.4 28.3 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR PAT1 PF09770.9 CDJ45784.1 - 1.9 6.7 50.6 2.1 6.5 50.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPX PF03105.19 CDJ45784.1 - 2.1 8.2 24.6 2.5 7.9 24.6 1.0 1 0 0 1 1 1 0 SPX domain Endostatin PF06482.11 CDJ45784.1 - 2.1 7.7 28.4 2.9 7.3 28.4 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SRP-alpha_N PF04086.13 CDJ45784.1 - 2.2 8.2 25.2 2.7 7.8 25.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FAM60A PF15396.6 CDJ45784.1 - 2.3 8.2 23.3 2.9 7.9 23.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 CDJ45784.1 - 2.9 6.8 28.0 3.3 6.6 28.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 AF-4 PF05110.13 CDJ45784.1 - 3.7 5.5 40.2 4.2 5.3 40.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PPP4R2 PF09184.11 CDJ45784.1 - 4.7 6.7 15.8 5.3 6.5 15.8 1.0 1 0 0 1 1 1 0 PPP4R2 VIR_N PF15912.5 CDJ45784.1 - 5.6 6.5 18.6 7.2 6.1 18.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal LAP1C PF05609.12 CDJ45784.1 - 6.5 5.7 30.1 7.6 5.5 30.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Paramyxo_ncap PF00973.19 CDJ45784.1 - 7.4 5.4 20.6 8.2 5.2 20.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Apt1 PF10351.9 CDJ45784.1 - 7.7 5.2 21.2 9.1 5.0 21.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain RIFIN PF02009.16 CDJ45784.1 - 8.9 6.1 18.7 9.9 6.0 18.7 1.0 1 0 0 1 1 1 0 Rifin CDC45 PF02724.14 CDJ45784.1 - 9 4.4 24.1 10 4.2 24.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Asp-B-Hydro_N PF05279.11 CDJ45784.1 - 9.4 6.2 22.0 11 6.0 22.0 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region WD40 PF00400.32 CDJ45785.1 - 4.4e-08 33.7 0.2 9.5e-08 32.6 0.2 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat RskA PF10099.9 CDJ45786.1 - 0.0014 18.9 0.0 0.0014 18.9 0.0 3.1 1 1 2 3 3 3 1 Anti-sigma-K factor rskA Caldesmon PF02029.15 CDJ45786.1 - 1.2 7.8 33.1 1.9 7.2 33.1 1.4 1 0 0 1 1 1 0 Caldesmon DUF1117 PF06547.12 CDJ45786.1 - 4.5 7.9 8.1 0.96 10.0 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) ALMT PF11744.8 CDJ45786.1 - 6 5.6 18.6 7.1 5.3 18.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PPR_3 PF13812.6 CDJ45787.1 - 0.0024 17.9 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PGM_PMM_I PF02878.16 CDJ45789.1 - 4.3e-10 39.4 0.3 4e-07 29.8 0.2 2.4 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Sporozoite_P67 PF05642.11 CDJ45789.1 - 7.2e-06 24.4 2.3 7.2e-06 24.4 2.3 1.4 1 1 0 1 1 1 1 Sporozoite P67 surface antigen RskA PF10099.9 CDJ45789.1 - 0.0011 19.4 10.2 0.0011 19.4 10.2 4.4 2 1 1 3 3 3 2 Anti-sigma-K factor rskA SPX PF03105.19 CDJ45789.1 - 0.0067 16.4 9.1 0.0067 16.4 9.1 2.2 2 0 0 2 2 2 1 SPX domain CCDC53 PF10152.9 CDJ45789.1 - 0.019 15.4 14.1 0.019 15.4 14.1 4.5 3 1 0 3 3 3 0 Subunit CCDC53 of WASH complex Lin-8 PF03353.15 CDJ45789.1 - 2.3 7.7 53.2 0.01 15.4 7.2 3.1 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist MMR1 PF08505.10 CDJ45789.1 - 2.3 8.4 49.6 0.4 10.9 18.6 3.3 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein Pex14_N PF04695.13 CDJ45790.1 - 0.81 10.3 21.4 0.95 10.1 21.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_23 PF13476.6 CDJ45790.1 - 1.7 9.1 12.6 1.9 8.9 12.6 1.1 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 CDJ45790.1 - 2.1 8.2 34.9 2.7 7.9 34.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ45790.1 - 2.6 5.9 9.8 2.8 5.7 9.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.7 CDJ45790.1 - 3 5.9 8.2 3.1 5.8 8.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CDJ45790.1 - 3.1 6.5 11.1 3.5 6.3 11.1 1.1 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 CDJ45790.1 - 4.9 6.4 16.3 6.4 6.1 16.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SARAF PF06682.12 CDJ45790.1 - 5 6.7 15.9 5.7 6.5 15.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis GN3L_Grn1 PF08701.11 CDJ45790.1 - 5.2 7.2 17.7 0.49 10.5 1.7 2.1 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase DUF1071 PF06378.11 CDJ45790.1 - 6.8 6.3 8.2 0.51 9.9 3.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1071) Neur_chan_memb PF02932.16 CDJ45790.1 - 7.1 6.6 7.3 7.7 6.5 7.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 CDJ45790.1 - 9.2 5.1 15.0 11 4.8 15.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FGE-sulfatase PF03781.16 CDJ45791.1 - 0.0069 16.0 4.5 0.008 15.8 4.5 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 FmiP_Thoc5 PF09766.9 CDJ45791.1 - 0.044 13.1 22.4 0.055 12.8 22.4 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 DUF5523 PF17661.1 CDJ45791.1 - 0.048 13.3 16.3 0.055 13.2 16.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) eIF-3_zeta PF05091.12 CDJ45791.1 - 0.099 11.6 25.0 0.12 11.3 25.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Anth_synt_I_N PF04715.13 CDJ45791.1 - 0.17 12.1 1.9 0.24 11.6 1.9 1.3 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region VIT PF08487.10 CDJ45791.1 - 0.58 10.4 0.0 0.58 10.4 0.0 2.2 1 1 1 2 2 2 0 Vault protein inter-alpha-trypsin domain MRP-S31 PF15433.6 CDJ45791.1 - 0.59 9.8 20.9 0.69 9.5 20.9 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 V_ATPase_I PF01496.19 CDJ45791.1 - 0.93 7.3 16.4 1.1 7.1 16.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ45791.1 - 2.5 6.8 24.2 2.9 6.6 24.2 1.1 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 CDJ45791.1 - 5.3 5.3 6.9 5.6 5.3 6.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AAA_23 PF13476.6 CDJ45791.1 - 5.4 7.5 24.6 6.7 7.2 24.6 1.1 1 0 0 1 1 1 0 AAA domain DUF2126 PF09899.9 CDJ45791.1 - 5.8 4.9 11.7 6.4 4.7 11.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CCSAP PF15748.5 CDJ45791.1 - 6 7.0 22.8 7.3 6.7 22.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ45791.1 - 7.6 6.3 19.2 10 5.9 19.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SPX PF03105.19 CDJ45792.1 - 0.0018 18.3 9.5 0.0018 18.3 9.5 3.4 2 1 0 2 2 2 1 SPX domain Herpes_pp85 PF04637.12 CDJ45792.1 - 3.9 5.8 13.6 7.5 4.9 13.6 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PAP_central PF04928.17 CDJ45793.1 - 5.9e-65 218.7 0.0 7.2e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 CDJ45793.1 - 6.3e-10 39.2 0.0 9.7e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 CDJ45793.1 - 0.029 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain SPX PF03105.19 CDJ45793.1 - 7.2 6.4 8.2 9.7 6.0 8.2 1.1 1 0 0 1 1 1 0 SPX domain TFIIF_alpha PF05793.12 CDJ45794.1 - 2.3 6.7 5.8 3.1 6.3 5.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Peptidase_S64 PF08192.11 CDJ45794.1 - 2.3 6.6 7.2 0.39 9.1 3.2 1.6 2 0 0 2 2 2 0 Peptidase family S64 RAP1 PF07218.11 CDJ45794.1 - 3 6.0 10.3 3.5 5.8 10.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Presenilin PF01080.17 CDJ45794.1 - 6 5.5 6.3 2.2 7.0 2.7 1.9 2 0 0 2 2 2 0 Presenilin Pet191_N PF10203.9 CDJ45795.1 - 0.02 15.2 0.5 0.069 13.5 0.5 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Hydrolase_3 PF08282.12 CDJ45796.1 - 9.7e-40 136.9 0.0 2e-36 126.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ45796.1 - 1.1e-10 41.4 0.0 3.8e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.16 CDJ45796.1 - 0.0087 15.2 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase IPI_T4 PF11634.8 CDJ45796.1 - 0.093 12.7 0.7 0.44 10.6 0.1 2.3 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 Hydrolase PF00702.26 CDJ45796.1 - 0.48 10.7 9.2 0.83 9.9 0.1 3.6 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase CDC48_N PF02359.18 CDJ45797.1 - 0.0018 18.4 0.0 0.26 11.5 0.0 2.5 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.6 CDJ45797.1 - 0.016 15.6 0.8 0.07 13.5 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain Glyco_hydro_3_C PF01915.22 CDJ45797.1 - 0.049 13.6 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain UTRA PF07702.13 CDJ45797.1 - 0.12 12.2 0.3 0.36 10.7 0.1 1.8 2 0 0 2 2 2 0 UTRA domain Molydop_binding PF01568.21 CDJ45797.1 - 0.18 11.8 0.0 1.1 9.4 0.0 1.9 1 1 1 2 2 2 0 Molydopterin dinucleotide binding domain Ribosomal_60s PF00428.19 CDJ45797.1 - 4.6 7.9 30.8 0.14 12.8 5.5 3.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF4667 PF15700.5 CDJ45798.1 - 0.0019 18.4 40.5 0.033 14.3 0.0 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ45798.1 - 0.32 11.0 80.9 0.062 13.3 36.2 4.4 5 0 0 5 5 5 0 Transcription factor IIA, alpha/beta subunit Rsc14 PF08586.10 CDJ45798.1 - 2.1 9.2 7.2 4.9 8.0 2.1 2.9 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DUF755 PF05501.11 CDJ45799.1 - 0.0074 16.6 17.8 0.0074 16.6 17.8 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF755) DUF4667 PF15700.5 CDJ45799.1 - 0.071 13.2 26.8 0.041 14.0 4.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) SKA1 PF07160.12 CDJ45799.1 - 0.08 12.8 9.9 0.17 11.7 9.9 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 MID_MedPIWI PF18296.1 CDJ45799.1 - 0.41 10.4 17.5 2.2 8.0 8.6 2.5 2 0 0 2 2 2 0 MID domain of medPIWI DUF4746 PF15928.5 CDJ45799.1 - 0.68 9.3 3.0 1 8.7 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Exonuc_VII_L PF02601.15 CDJ45799.1 - 0.77 9.3 10.7 2 7.9 10.7 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit TERB2 PF15101.6 CDJ45799.1 - 4.7 7.2 8.7 10 6.1 8.7 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Apt1 PF10351.9 CDJ45799.1 - 7.5 5.3 24.5 1.7 7.4 8.3 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF3533 PF12051.8 CDJ45799.1 - 9.4 5.0 8.5 15 4.4 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) SR-25 PF10500.9 CDJ45801.1 - 0.00012 21.8 60.8 0.00084 19.0 21.8 2.3 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ45801.1 - 0.0071 16.6 23.8 0.0071 16.6 23.8 3.8 3 1 1 4 4 2 1 Domain of unknown function (DUF755) DUF2681 PF10883.8 CDJ45801.1 - 0.015 15.7 5.8 0.015 15.7 5.8 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2681) DUF1387 PF07139.11 CDJ45801.1 - 0.2 11.4 24.8 0.38 10.4 24.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PepSY_TM PF03929.16 CDJ45801.1 - 0.28 10.8 8.0 0.92 9.1 1.6 2.3 2 0 0 2 2 2 0 PepSY-associated TM region Nop53 PF07767.11 CDJ45801.1 - 0.3 10.4 30.2 0.099 12.0 14.5 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Med3 PF11593.8 CDJ45801.1 - 0.43 9.7 24.5 0.094 11.9 8.1 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF4667 PF15700.5 CDJ45801.1 - 0.66 10.0 34.0 0.32 11.0 10.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Filament_head PF04732.14 CDJ45801.1 - 0.7 10.8 33.7 0.2 12.5 6.1 2.3 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region RSRP PF17069.5 CDJ45801.1 - 1.1 8.8 40.3 0.73 9.4 10.4 2.5 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 RIO1 PF01163.22 CDJ45801.1 - 1.1 8.8 9.0 0.057 13.0 3.1 1.8 2 1 1 3 3 3 0 RIO1 family Spt20 PF12090.8 CDJ45801.1 - 1.8 8.2 53.8 0.49 10.0 24.0 2.5 3 0 0 3 3 3 0 Spt20 family DDRGK PF09756.9 CDJ45801.1 - 3.9 7.0 33.2 0.16 11.6 10.4 2.9 3 0 0 3 3 3 0 DDRGK domain LIM_bind PF01803.16 CDJ45801.1 - 7.8 5.9 22.1 0.57 9.7 7.7 2.2 2 0 0 2 2 2 0 LIM-domain binding protein CCDC106 PF15794.5 CDJ45801.1 - 9.5 5.9 36.0 9.4 5.9 13.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 PepSY_TM PF03929.16 CDJ45804.1 - 0.12 12.0 0.9 0.19 11.4 0.9 1.4 1 0 0 1 1 1 0 PepSY-associated TM region Apt1 PF10351.9 CDJ45804.1 - 0.36 9.6 15.4 0.049 12.5 12.0 1.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain RAP1 PF07218.11 CDJ45804.1 - 0.62 8.3 20.3 0.77 8.0 20.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CytochromB561_N PF09786.9 CDJ45804.1 - 1.1 8.2 15.1 1.4 7.8 15.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal NAM-associated PF14303.6 CDJ45804.1 - 1.6 9.4 22.4 21 5.8 22.4 2.1 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain AAR2 PF05282.11 CDJ45804.1 - 2.4 7.5 7.6 3.9 6.8 7.6 1.3 1 0 0 1 1 1 0 AAR2 protein DUF4614 PF15391.6 CDJ45804.1 - 3.6 7.5 20.6 0.38 10.7 15.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DHHW PF14286.6 CDJ45804.1 - 4.6 6.5 8.0 6.4 6.0 8.0 1.2 1 0 0 1 1 1 0 DHHW protein ANAPC1 PF12859.7 CDJ45804.1 - 4.8 7.8 15.3 10 6.7 15.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Telomerase_RBD PF12009.8 CDJ45805.1 - 2.6e-25 89.1 13.9 2.6e-25 89.1 13.9 8.2 6 3 0 6 6 6 1 Telomerase ribonucleoprotein complex - RNA binding domain NAM-associated PF14303.6 CDJ45805.1 - 1.4e-05 25.8 0.1 1.4e-05 25.8 0.1 18.1 12 4 8 20 20 20 2 No apical meristem-associated C-terminal domain Macoilin PF09726.9 CDJ45805.1 - 1.8e-05 23.6 51.0 1.8e-05 23.6 51.0 11.7 7 3 1 10 10 10 2 Macoilin family Activator_LAG-3 PF11498.8 CDJ45805.1 - 3.3e-05 23.1 37.9 3.3e-05 23.1 37.9 14.7 11 2 3 14 14 14 1 Transcriptional activator LAG-3 SUIM_assoc PF16619.5 CDJ45805.1 - 0.00059 19.9 2.7 0.00059 19.9 2.7 37.5 10 8 8 18 18 18 1 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 CDJ45807.1 - 1.1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP PF00188.26 CDJ45808.1 - 3.8e-09 37.4 5.5 2.5e-08 34.8 5.5 2.3 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CLTH PF10607.9 CDJ45809.1 - 0.036 14.0 0.7 0.057 13.3 0.7 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain SUIM_assoc PF16619.5 CDJ45809.1 - 1.5 8.9 17.5 1.2 9.3 7.4 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AAA_23 PF13476.6 CDJ45809.1 - 9.6 6.6 10.1 6.3 7.3 4.9 2.3 2 0 0 2 2 2 0 AAA domain OmpH PF03938.14 CDJ45809.1 - 9.7 6.5 26.4 6.5 7.1 12.8 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) p25-alpha PF05517.12 CDJ45810.1 - 1e-36 126.4 3.2 1.2e-36 126.3 3.2 1.0 1 0 0 1 1 1 1 p25-alpha Toprim_C_rpt PF13368.6 CDJ45810.1 - 0.092 12.8 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat SET PF00856.28 CDJ45811.1 - 1.2e-06 29.0 20.4 2.9e-06 27.8 12.2 3.7 2 1 0 2 2 2 1 SET domain ISP3_C PF18045.1 CDJ45812.1 - 3.3e-27 94.5 0.0 4e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 ISP3 C-terminal ISP1_C PF18161.1 CDJ45812.1 - 1.3e-20 73.4 0.0 1.6e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 ISP1 C-terminal TGS PF02824.21 CDJ45812.1 - 0.15 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 TGS domain DUF789 PF05623.12 CDJ45813.1 - 2.2e-14 53.9 0.0 2.2e-14 53.9 0.0 13.6 10 4 2 12 12 12 1 Protein of unknown function (DUF789) Ribosomal_60s PF00428.19 CDJ45815.1 - 0.01 16.4 39.4 0.3 11.7 17.3 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Mod_r PF07200.13 CDJ45815.1 - 0.058 13.5 1.4 0.072 13.2 1.4 1.2 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein NDUF_B12 PF08122.12 CDJ45815.1 - 0.18 11.9 0.2 0.18 11.9 0.2 2.9 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DSBA PF01323.20 CDJ45815.1 - 0.29 10.9 15.5 0.37 10.6 15.5 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Fes1 PF08609.10 CDJ45815.1 - 0.73 10.8 4.8 1.1 10.2 4.8 1.4 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 Stevor PF17410.2 CDJ45815.1 - 3.7 7.0 7.1 4.5 6.7 7.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Acyl-CoA_dh_1 PF00441.24 CDJ45815.1 - 5.4 7.2 22.5 7.1 6.8 22.5 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain SARAF PF06682.12 CDJ45816.1 - 0.0036 17.0 5.1 0.0063 16.2 5.1 1.4 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis eIF-3_zeta PF05091.12 CDJ45816.1 - 0.16 10.9 2.0 0.24 10.4 2.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Phostensin_N PF13916.6 CDJ45816.1 - 0.82 10.0 5.9 10 6.6 1.1 3.0 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal MS_channel PF00924.18 CDJ45817.1 - 1.5e-11 44.2 1.6 2.3e-11 43.6 1.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Shadoo PF14999.6 CDJ45818.1 - 0.0028 17.8 5.6 0.0036 17.4 5.6 1.2 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective DUF4179 PF13786.6 CDJ45818.1 - 0.014 15.9 3.1 0.024 15.1 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DcuA_DcuB PF03605.14 CDJ45818.1 - 0.03 13.2 4.6 0.044 12.7 4.6 1.4 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Ureide_permease PF07168.11 CDJ45818.1 - 0.045 12.5 2.2 0.045 12.5 2.2 1.2 1 0 0 1 1 1 0 Ureide permease MAJIN PF15077.6 CDJ45818.1 - 0.053 13.3 4.3 0.061 13.1 4.3 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Photo_RC PF00124.19 CDJ45818.1 - 0.085 12.1 2.1 0.12 11.6 2.1 1.3 1 1 0 1 1 1 0 Photosynthetic reaction centre protein CD20 PF04103.15 CDJ45818.1 - 0.1 12.7 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 CD20-like family SID-1_RNA_chan PF13965.6 CDJ45818.1 - 0.1 11.0 2.1 0.093 11.1 2.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SpoIIP PF07454.11 CDJ45818.1 - 0.1 12.0 10.3 0.11 11.9 10.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CDJ45818.1 - 0.13 11.0 14.3 0.13 11.0 14.3 1.1 1 0 0 1 1 1 0 Presenilin FHIPEP PF00771.20 CDJ45818.1 - 0.15 10.5 12.3 0.19 10.2 12.3 1.1 1 0 0 1 1 1 0 FHIPEP family Velvet PF11754.8 CDJ45818.1 - 0.33 10.8 11.7 0.39 10.6 11.7 1.1 1 0 0 1 1 1 0 Velvet factor Band_3_cyto PF07565.13 CDJ45818.1 - 0.44 10.3 12.2 0.51 10.1 12.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Serinc PF03348.15 CDJ45818.1 - 0.44 9.4 7.3 0.44 9.4 7.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) eIF-3_zeta PF05091.12 CDJ45818.1 - 0.79 8.6 16.7 0.75 8.7 16.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EOS1 PF12326.8 CDJ45818.1 - 0.84 9.5 4.8 0.83 9.6 4.8 1.2 1 0 0 1 1 1 0 N-glycosylation protein Neur_chan_memb PF02932.16 CDJ45818.1 - 0.84 9.6 8.2 0.84 9.7 8.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF913 PF06025.12 CDJ45818.1 - 0.87 8.5 7.7 0.83 8.6 7.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) R_equi_Vir PF05526.11 CDJ45818.1 - 0.92 9.3 14.2 1.2 8.9 14.2 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RR_TM4-6 PF06459.12 CDJ45818.1 - 0.92 9.3 12.5 0.85 9.4 12.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CDJ45818.1 - 0.96 9.6 12.3 1 9.4 12.3 1.1 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 CDJ45818.1 - 1.4 6.8 13.1 1.2 6.9 13.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cytochrom_C552 PF02335.15 CDJ45818.1 - 1.4 7.7 18.4 1.6 7.6 18.4 1.0 1 0 0 1 1 1 0 Cytochrome c552 BAF1_ABF1 PF04684.13 CDJ45818.1 - 1.5 7.8 17.4 1.8 7.5 17.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor 2HCT PF03390.15 CDJ45818.1 - 1.7 7.2 5.4 2 6.9 5.4 1.1 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family CSG2 PF16965.5 CDJ45818.1 - 2.1 7.2 4.7 1.8 7.4 4.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator TERB2 PF15101.6 CDJ45818.1 - 2.2 8.3 18.5 0.18 11.8 14.3 1.4 2 0 0 2 2 1 0 Telomere-associated protein TERB2 DUF1980 PF09323.10 CDJ45818.1 - 3 7.7 11.5 4.2 7.2 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Hid1 PF12722.7 CDJ45818.1 - 3.4 5.7 10.4 2.8 6.0 10.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EMC3_TMCO1 PF01956.16 CDJ45818.1 - 3.6 7.3 9.6 5.4 6.7 9.6 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Trp_oprn_chp PF09534.10 CDJ45818.1 - 5 6.9 21.3 9.3 6.0 21.3 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4228 PF14009.6 CDJ45818.1 - 5.1 7.4 11.5 6.6 7.1 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Coilin_N PF15862.5 CDJ45818.1 - 5.2 6.9 17.0 8.8 6.1 17.0 1.5 1 0 0 1 1 1 0 Coilin N-terminus CLN3 PF02487.17 CDJ45818.1 - 7.1 5.6 8.9 7.6 5.5 8.9 1.1 1 0 0 1 1 1 0 CLN3 protein AIF_C PF14721.6 CDJ45818.1 - 8.5 6.7 14.0 13 6.2 14.0 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4834 PF16118.5 CDJ45818.1 - 9.7 7.2 18.4 0.4 11.7 12.7 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) SR-25 PF10500.9 CDJ45819.1 - 0.00047 19.8 16.8 0.00069 19.3 16.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ45819.1 - 0.41 11.2 21.2 0.49 10.9 21.2 1.0 1 0 0 1 1 1 0 TCP family transcription factor CCSAP PF15748.5 CDJ45819.1 - 1.5 8.9 23.6 1.7 8.7 23.6 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Hormone_1 PF00103.20 CDJ45819.1 - 1.6 8.4 11.5 2.1 8.1 11.5 1.1 1 0 0 1 1 1 0 Somatotropin hormone family Pex14_N PF04695.13 CDJ45819.1 - 2.3 8.9 29.1 2.8 8.6 29.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region STAC2_u1 PF16664.5 CDJ45819.1 - 4.1 7.9 18.1 5 7.6 18.1 1.1 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 IMUP PF15761.5 CDJ45819.1 - 6 7.6 19.2 1.3 9.8 14.8 1.9 1 1 1 2 2 2 0 Immortalisation up-regulated protein PAT1 PF09770.9 CDJ45819.1 - 6.5 4.9 25.8 6.2 5.0 25.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.10 CDJ45819.1 - 7.5 5.1 42.7 7.5 5.1 42.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TAF4 PF05236.14 CDJ45820.1 - 0.027 14.2 14.1 0.029 14.1 14.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SARAF PF06682.12 CDJ45820.1 - 0.05 13.2 12.0 0.059 13.0 12.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis V_ATPase_I PF01496.19 CDJ45820.1 - 0.087 10.7 15.9 0.089 10.7 15.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SCIMP PF15050.6 CDJ45820.1 - 0.13 12.7 5.6 0.18 12.3 5.6 1.2 1 0 0 1 1 1 0 SCIMP protein FAM60A PF15396.6 CDJ45820.1 - 0.17 11.9 11.2 0.17 11.8 11.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.17 CDJ45820.1 - 0.38 10.9 13.1 0.48 10.5 13.1 1.2 1 0 0 1 1 1 0 DDHD domain CCSAP PF15748.5 CDJ45820.1 - 0.41 10.8 18.6 0.47 10.6 18.6 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Zip PF02535.22 CDJ45820.1 - 0.63 9.2 8.0 0.7 9.1 8.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pex16 PF08610.10 CDJ45820.1 - 0.63 9.1 6.3 0.78 8.8 6.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Neur_chan_memb PF02932.16 CDJ45820.1 - 0.64 10.0 14.7 0.66 10.0 14.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 CDJ45820.1 - 0.87 8.4 7.0 1.2 8.0 7.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Exonuc_VII_L PF02601.15 CDJ45820.1 - 0.88 9.1 20.1 0.94 9.0 20.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SLC12 PF03522.15 CDJ45820.1 - 0.94 8.4 16.7 1.1 8.2 16.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 YABBY PF04690.13 CDJ45820.1 - 0.96 10.0 11.9 1.3 9.6 11.9 1.2 1 0 0 1 1 1 0 YABBY protein SKA1 PF07160.12 CDJ45820.1 - 1 9.2 21.5 1.2 9.0 21.5 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 TFIIA PF03153.13 CDJ45820.1 - 1 9.3 42.3 1.2 9.0 42.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FapA PF03961.13 CDJ45820.1 - 1.2 7.7 13.4 1.2 7.6 13.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A RR_TM4-6 PF06459.12 CDJ45820.1 - 1.3 8.8 16.2 1.4 8.7 16.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.9 CDJ45820.1 - 1.3 9.1 10.1 1.6 8.8 10.1 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2828 PF11443.8 CDJ45820.1 - 1.3 7.0 14.7 1.5 6.8 14.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PAT1 PF09770.9 CDJ45820.1 - 1.5 7.0 29.6 1.5 7.0 29.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.7 CDJ45820.1 - 2 6.5 17.0 2.3 6.2 17.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CDJ45820.1 - 2 7.1 21.6 2.4 6.8 21.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 CDJ45820.1 - 2.1 7.7 13.0 2.5 7.4 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Lin-8 PF03353.15 CDJ45820.1 - 2.2 7.8 22.8 2.5 7.6 22.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4569 PF15133.6 CDJ45820.1 - 2.6 7.7 20.4 3.3 7.4 20.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) CENP-H PF05837.12 CDJ45820.1 - 3 8.3 22.4 5 7.6 22.4 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ALMT PF11744.8 CDJ45820.1 - 3.1 6.5 13.2 3.2 6.5 13.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CSG2 PF16965.5 CDJ45820.1 - 3.3 6.6 5.6 3.8 6.4 5.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator SID-1_RNA_chan PF13965.6 CDJ45820.1 - 3.3 6.0 4.8 3.9 5.8 4.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hydin_ADK PF17213.3 CDJ45820.1 - 3.4 7.9 13.9 4.1 7.6 13.9 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain HemX PF04375.14 CDJ45820.1 - 3.5 6.8 37.9 4.2 6.5 37.9 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Herpes_DNAp_acc PF04929.12 CDJ45820.1 - 3.5 6.5 10.7 4.6 6.1 10.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Membralin PF09746.9 CDJ45820.1 - 3.6 6.5 9.1 4 6.4 9.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein Phage_GPO PF05929.11 CDJ45820.1 - 4.1 7.0 18.3 4.7 6.8 18.3 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CLN3 PF02487.17 CDJ45820.1 - 4.6 6.2 11.2 6.3 5.7 11.2 1.2 1 0 0 1 1 1 0 CLN3 protein XRN_M PF17846.1 CDJ45820.1 - 5.2 5.9 12.7 6 5.7 12.7 1.0 1 0 0 1 1 1 0 Xrn1 helical domain PTPRCAP PF15713.5 CDJ45820.1 - 6.1 7.1 20.5 10 6.4 20.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Band_3_cyto PF07565.13 CDJ45820.1 - 6.2 6.5 16.1 8.2 6.1 16.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4175 PF13779.6 CDJ45820.1 - 6.3 4.6 45.9 7.5 4.3 45.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MRP-S26 PF14943.6 CDJ45820.1 - 7.5 6.4 22.2 9.8 6.0 22.2 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Borrelia_P83 PF05262.11 CDJ45820.1 - 7.7 4.9 26.6 9.3 4.6 26.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein FdhD-NarQ PF02634.15 CDJ45820.1 - 8.9 5.9 7.6 10 5.7 7.6 1.1 1 0 0 1 1 1 0 FdhD/NarQ family Kei1 PF08552.11 CDJ45820.1 - 9.2 6.1 8.6 14 5.5 8.6 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 YPEB PF14620.6 CDJ45821.1 - 0.00049 19.5 8.8 0.00076 18.9 8.8 1.2 1 0 0 1 1 1 1 YpeB sporulation LCD1 PF09798.9 CDJ45821.1 - 0.01 14.4 0.7 0.013 14.0 0.7 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein XRCC4 PF06632.12 CDJ45821.1 - 0.012 14.4 9.9 0.022 13.6 9.9 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 UPF0172 PF03665.13 CDJ45821.1 - 0.27 11.3 6.5 0.068 13.2 2.7 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) PRCC PF10253.9 CDJ45821.1 - 3 8.6 29.7 0.29 11.9 23.4 1.9 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF812 PF05667.11 CDJ45821.1 - 4.6 6.0 19.2 1.3 7.8 16.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.19 CDJ45821.1 - 5.7 4.7 8.3 8.5 4.2 8.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SR-25 PF10500.9 CDJ45821.1 - 6.9 6.2 23.4 0.51 9.9 6.0 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CDJ45821.1 - 8 4.6 6.5 10 4.2 6.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GrpE PF01025.19 CDJ45821.1 - 9.4 5.9 11.0 1.7 8.3 6.7 1.8 1 1 0 1 1 1 0 GrpE SR-25 PF10500.9 CDJ45822.1 - 0.00084 19.0 26.2 0.00084 19.0 26.2 7.1 2 2 5 8 8 8 1 Nuclear RNA-splicing-associated protein CPSF100_C PF13299.6 CDJ45825.1 - 0.052 13.7 2.7 0.066 13.4 0.1 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Apc15p PF05841.11 CDJ45825.1 - 3.3 8.5 8.0 0.76 10.6 1.3 2.2 2 0 0 2 2 2 0 Apc15p protein RskA PF10099.9 CDJ45825.1 - 6 7.1 31.3 0.039 14.3 1.6 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA SOBP PF15279.6 CDJ45825.1 - 7.3 7.1 13.2 9.3 6.8 13.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4834 PF16118.5 CDJ45825.1 - 9.1 7.3 7.1 1.8 9.6 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) NARP1 PF12569.8 CDJ45826.1 - 0.046 12.6 25.3 0.052 12.5 25.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Gti1_Pac2 PF09729.9 CDJ45826.1 - 0.13 12.4 19.4 0.15 12.1 19.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family V_ATPase_I PF01496.19 CDJ45826.1 - 0.18 9.7 23.1 0.2 9.5 23.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2828 PF11443.8 CDJ45826.1 - 0.19 9.7 24.5 0.21 9.7 24.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) GAGA_bind PF06217.12 CDJ45826.1 - 0.31 11.3 22.5 0.34 11.2 22.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 CDJ45826.1 - 0.58 9.9 30.8 0.66 9.8 30.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ45826.1 - 0.59 9.1 27.0 0.66 8.9 27.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Rtf2 PF04641.12 CDJ45826.1 - 0.74 9.1 24.3 0.87 8.9 24.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Presenilin PF01080.17 CDJ45826.1 - 1 8.1 33.6 1.2 7.9 33.6 1.0 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 CDJ45826.1 - 1.5 7.7 14.5 1.8 7.5 14.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Velvet PF11754.8 CDJ45826.1 - 1.5 8.7 21.4 2 8.3 21.4 1.2 1 0 0 1 1 1 0 Velvet factor Neur_chan_memb PF02932.16 CDJ45826.1 - 1.7 8.6 22.4 1.9 8.5 22.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.6 CDJ45826.1 - 1.8 8.4 32.5 2.2 8.2 32.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO ALMT PF11744.8 CDJ45826.1 - 2 7.2 21.8 2.3 7.0 21.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SAPS PF04499.15 CDJ45826.1 - 2 7.1 19.6 2.3 6.9 19.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Endostatin PF06482.11 CDJ45826.1 - 2 7.8 25.5 2.4 7.5 25.5 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF2464 PF10240.9 CDJ45826.1 - 2.3 7.7 16.4 2.6 7.5 16.4 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 DUF3807 PF12720.7 CDJ45826.1 - 2.5 8.3 36.8 3.3 7.9 36.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) PolyA_pol PF01743.20 CDJ45826.1 - 2.9 8.3 9.3 3.4 8.1 9.3 1.1 1 0 0 1 1 1 0 Poly A polymerase head domain BORG_CEP PF14957.6 CDJ45826.1 - 2.9 9.1 18.3 4.1 8.6 18.3 1.3 1 0 0 1 1 1 0 Cdc42 effector CENP-N PF05238.13 CDJ45826.1 - 3.1 7.0 21.4 3.5 6.8 21.4 1.0 1 0 0 1 1 1 0 Kinetochore protein CHL4 like CLN3 PF02487.17 CDJ45826.1 - 3.4 6.6 18.3 4.1 6.3 18.3 1.2 1 0 0 1 1 1 0 CLN3 protein Pannexin_like PF12534.8 CDJ45826.1 - 3.9 6.5 17.1 5.2 6.0 17.1 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 NPR3 PF03666.13 CDJ45826.1 - 4.2 6.1 29.7 4.7 5.9 29.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MAJIN PF15077.6 CDJ45826.1 - 4.4 7.0 22.5 5 6.8 22.5 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein SelP_N PF04592.14 CDJ45826.1 - 5.1 6.4 25.7 5.5 6.3 25.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2126 PF09899.9 CDJ45826.1 - 5.3 5.0 18.7 6.8 4.6 18.7 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) FAM60A PF15396.6 CDJ45826.1 - 7 6.6 25.3 9.2 6.2 25.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF4569 PF15133.6 CDJ45826.1 - 7.3 6.2 27.3 8.7 6.0 27.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Membralin PF09746.9 CDJ45826.1 - 8.8 5.2 18.0 9.9 5.1 18.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein VIR_N PF15912.5 CDJ45826.1 - 9.2 5.8 19.3 11 5.5 19.3 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal CDC45 PF02724.14 CDJ45826.1 - 9.5 4.4 32.2 11 4.2 32.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Activator_LAG-3 PF11498.8 CDJ45827.1 - 0.0027 16.8 7.9 0.0029 16.6 7.9 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 YkyB PF14177.6 CDJ45827.1 - 0.025 14.9 3.3 0.037 14.3 3.3 1.2 1 0 0 1 1 1 0 YkyB-like protein Oxidored_FMN PF00724.20 CDJ45827.1 - 0.072 12.3 4.1 0.096 11.9 4.1 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Spt20 PF12090.8 CDJ45827.1 - 0.16 11.6 11.6 0.19 11.3 11.6 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ45827.1 - 0.18 11.8 13.9 0.2 11.6 13.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VSG_B PF13206.6 CDJ45827.1 - 0.21 10.8 11.8 0.24 10.6 11.8 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF2232 PF09991.9 CDJ45827.1 - 0.25 10.5 0.9 0.29 10.3 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Myb_Cef PF11831.8 CDJ45827.1 - 0.34 10.4 10.7 0.86 9.1 10.7 1.7 1 1 0 1 1 1 0 pre-mRNA splicing factor component RskA PF10099.9 CDJ45827.1 - 0.98 9.7 14.0 1.2 9.4 14.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA UCH PF00443.29 CDJ45828.1 - 2e-05 24.2 7.7 2e-05 24.2 7.7 5.7 3 2 1 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase SR-25 PF10500.9 CDJ45829.1 - 0.001 18.7 11.2 0.001 18.7 11.2 4.9 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein CNDH2_M PF16869.5 CDJ45830.1 - 0.12 13.0 0.1 0.12 13.0 0.1 4.1 4 0 0 4 4 4 0 PF16858 Hep_59 PF07052.11 CDJ45830.1 - 9.5 7.0 20.5 0.33 11.7 0.3 4.2 4 0 0 4 4 4 0 Hepatocellular carcinoma-associated antigen 59 BAF1_ABF1 PF04684.13 CDJ45832.1 - 0.0034 16.5 1.0 0.0075 15.4 0.0 1.9 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor zf-CHC2 PF01807.20 CDJ45832.1 - 0.064 13.1 0.6 0.17 11.7 0.6 1.7 1 0 0 1 1 1 0 CHC2 zinc finger TFIIA PF03153.13 CDJ45832.1 - 0.26 11.2 35.6 0.58 10.1 23.9 3.0 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ45833.1 - 1.5e-06 27.4 63.8 0.00049 19.2 7.4 5.1 5 0 0 5 5 5 4 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ45833.1 - 7.2e-06 26.4 4.1 7.2e-06 26.4 4.1 5.1 2 1 3 5 5 5 1 Anti-sigma-K factor rskA Isy1 PF06246.12 CDJ45833.1 - 0.0015 18.2 23.9 0.074 12.6 3.0 3.3 3 0 0 3 3 3 3 Isy1-like splicing family Spt20 PF12090.8 CDJ45833.1 - 0.0028 17.3 12.8 0.0028 17.3 12.8 5.3 4 1 1 5 5 5 3 Spt20 family MTS PF05175.14 CDJ45833.1 - 0.069 12.7 1.5 0.093 12.3 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Eapp_C PF10238.9 CDJ45833.1 - 0.58 10.2 29.6 0.88 9.6 2.4 4.5 4 0 0 4 4 4 0 E2F-associated phosphoprotein SpoIIP PF07454.11 CDJ45833.1 - 1.9 7.9 30.9 1.9 7.9 4.6 4.2 4 0 0 4 4 4 0 Stage II sporulation protein P (SpoIIP) Rxt3 PF08642.10 CDJ45833.1 - 4.6 8.0 19.5 24 5.7 0.7 4.5 4 0 0 4 4 4 0 Histone deacetylation protein Rxt3 DUF3408 PF11888.8 CDJ45833.1 - 6.3 6.9 36.1 1.3 9.1 4.4 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3408) RskA PF10099.9 CDJ45834.1 - 4e-05 24.0 6.9 0.00016 22.1 7.0 1.8 1 1 0 1 1 1 1 Anti-sigma-K factor rskA DUF812 PF05667.11 CDJ45834.1 - 0.0054 15.7 25.7 0.0066 15.4 25.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) GREB1 PF15782.5 CDJ45834.1 - 0.21 8.7 23.4 0.24 8.5 23.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CDJ45834.1 - 0.3 11.1 42.8 0.38 10.7 42.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 CDJ45834.1 - 0.46 9.1 22.2 0.65 8.6 22.2 1.2 1 0 0 1 1 1 0 Hamartin protein SR-25 PF10500.9 CDJ45834.1 - 0.59 9.7 50.5 0.36 10.4 25.3 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4551 PF15087.6 CDJ45834.1 - 0.88 8.3 23.1 0.91 8.3 23.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SLC12 PF03522.15 CDJ45834.1 - 1.1 8.1 17.7 1.4 7.8 17.7 1.3 1 0 0 1 1 1 0 Solute carrier family 12 LAP1C PF05609.12 CDJ45834.1 - 1.3 8.1 26.1 1.6 7.8 26.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 CDJ45834.1 - 1.3 7.2 15.6 1.7 6.9 15.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 CDJ45834.1 - 1.7 7.2 23.9 1.9 7.0 23.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FtsK_alpha PF17854.1 CDJ45834.1 - 2.4 8.3 6.6 3.9 7.7 5.1 2.1 1 1 1 2 2 2 0 FtsK alpha domain LMBR1 PF04791.16 CDJ45834.1 - 2.4 6.9 11.9 2.6 6.8 11.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RRT14 PF17075.5 CDJ45834.1 - 2.4 8.2 25.2 3.7 7.6 25.2 1.3 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 DUF4698 PF15769.5 CDJ45834.1 - 3.1 6.7 23.3 4.2 6.3 23.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Utp14 PF04615.13 CDJ45834.1 - 4.2 5.8 23.0 5.1 5.5 23.0 1.0 1 0 0 1 1 1 0 Utp14 protein GET2 PF08690.10 CDJ45834.1 - 4.3 6.9 24.4 4.6 6.8 23.8 1.3 1 1 0 1 1 1 0 GET complex subunit GET2 Hid1 PF12722.7 CDJ45834.1 - 4.4 5.3 24.0 5.3 5.0 24.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPP4R2 PF09184.11 CDJ45834.1 - 5.4 6.5 19.6 7 6.2 19.6 1.1 1 0 0 1 1 1 0 PPP4R2 PAT1 PF09770.9 CDJ45834.1 - 6.7 4.8 26.7 7.9 4.6 26.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0113_N PF17833.1 CDJ45835.1 - 1.7e-26 92.6 0.0 2.6e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CDJ45835.1 - 6.8e-17 61.5 0.0 1.3e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain OmpH PF03938.14 CDJ45836.1 - 0.033 14.5 0.1 0.052 13.9 0.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.25 CDJ45837.1 - 3.2e-57 193.9 0.0 6.2e-57 193.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ45837.1 - 7.5e-36 123.7 0.0 1.4e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ45837.1 - 0.0004 19.3 0.1 0.0029 16.4 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CDJ45837.1 - 0.31 10.9 0.0 0.31 10.9 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Exonuc_VII_L PF02601.15 CDJ45837.1 - 1.2 8.6 6.5 2.1 7.8 6.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prenyltrans PF00432.21 CDJ45838.1 - 4.9e-14 51.8 19.0 0.034 13.9 0.0 7.8 8 0 0 8 8 8 5 Prenyltransferase and squalene oxidase repeat CSD PF00313.22 CDJ45839.1 - 4.4e-23 80.9 0.4 6.2e-23 80.4 0.4 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 CDJ45839.1 - 0.0047 16.6 0.2 0.009 15.7 0.2 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain PP2C PF00481.21 CDJ45841.1 - 1.5e-23 83.8 0.0 2.3e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Trehalase PF01204.18 CDJ45842.1 - 3.9e-47 161.2 0.2 4.9e-47 160.9 0.2 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 CDJ45842.1 - 8.2e-06 25.0 0.1 1.2e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DHODB_Fe-S_bind PF10418.9 CDJ45842.1 - 0.082 12.7 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B TMEM214 PF10151.9 CDJ45843.1 - 0.34 9.3 0.6 0.72 8.2 0.6 1.4 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Utp14 PF04615.13 CDJ45844.1 - 4.4e-06 25.6 7.4 4.4e-06 25.6 7.4 5.7 2 2 1 4 4 4 1 Utp14 protein Histone PF00125.24 CDJ45845.1 - 9.1e-16 58.4 0.1 1.1e-15 58.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 CDJ45845.1 - 0.00036 20.9 0.0 0.00061 20.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 CDJ45845.1 - 0.0027 18.0 0.5 0.0055 17.0 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4615 PF15393.6 CDJ45846.1 - 0.054 14.1 1.3 0.07 13.7 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) NOA36 PF06524.12 CDJ45846.1 - 0.06 12.7 0.2 0.069 12.5 0.2 1.0 1 0 0 1 1 1 0 NOA36 protein FAM101 PF15068.6 CDJ45846.1 - 0.4 10.6 2.6 0.52 10.2 2.6 1.1 1 0 0 1 1 1 0 FAM101 family DUF1180 PF06679.12 CDJ45846.1 - 5.1 7.5 11.6 6.2 7.2 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Presenilin PF01080.17 CDJ45846.1 - 8.4 5.0 8.2 9.5 4.9 8.2 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ45847.1 - 0.045 12.7 25.1 0.053 12.5 25.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 CDJ45847.1 - 0.052 13.4 22.6 0.055 13.3 22.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CDJ45847.1 - 0.057 13.6 18.9 0.077 13.2 18.9 1.3 1 0 0 1 1 1 0 DDHD domain DUF1387 PF07139.11 CDJ45847.1 - 0.11 12.2 19.6 0.11 12.2 19.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Med19 PF10278.9 CDJ45847.1 - 0.16 11.9 12.2 0.2 11.6 12.2 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Neur_chan_memb PF02932.16 CDJ45847.1 - 0.27 11.2 17.5 0.28 11.2 17.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Velvet PF11754.8 CDJ45847.1 - 0.27 11.1 19.3 0.32 10.9 19.3 1.2 1 0 0 1 1 1 0 Velvet factor Presenilin PF01080.17 CDJ45847.1 - 0.28 9.9 29.4 0.28 9.9 29.4 1.1 1 0 0 1 1 1 0 Presenilin CCSAP PF15748.5 CDJ45847.1 - 0.3 11.2 26.1 0.3 11.2 26.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TFIIA PF03153.13 CDJ45847.1 - 0.33 10.9 59.4 0.35 10.8 59.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5427 PF10310.9 CDJ45847.1 - 0.33 9.9 27.7 0.37 9.7 27.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF913 PF06025.12 CDJ45847.1 - 0.34 9.8 13.5 0.38 9.7 13.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Endostatin PF06482.11 CDJ45847.1 - 0.36 10.2 19.1 0.39 10.1 19.1 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SID-1_RNA_chan PF13965.6 CDJ45847.1 - 0.44 8.9 7.8 0.45 8.9 7.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BORG_CEP PF14957.6 CDJ45847.1 - 0.47 11.6 12.7 0.58 11.3 12.7 1.3 1 0 0 1 1 1 0 Cdc42 effector Tim54 PF11711.8 CDJ45847.1 - 0.55 9.0 17.6 0.78 8.5 17.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2052 PF09747.9 CDJ45847.1 - 0.65 10.1 24.0 0.68 10.0 24.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SpoIIP PF07454.11 CDJ45847.1 - 0.65 9.4 21.5 1.1 8.7 21.5 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) UPF0564 PF10595.9 CDJ45847.1 - 0.66 9.0 35.0 0.73 8.8 35.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 PPP4R2 PF09184.11 CDJ45847.1 - 0.74 9.3 10.7 0.79 9.3 10.7 1.1 1 0 0 1 1 1 0 PPP4R2 Hid1 PF12722.7 CDJ45847.1 - 0.84 7.7 21.0 0.78 7.8 21.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PA26 PF04636.13 CDJ45847.1 - 1 8.2 18.4 1 8.2 18.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4569 PF15133.6 CDJ45847.1 - 1.2 8.8 24.3 1.5 8.5 24.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) VIR_N PF15912.5 CDJ45847.1 - 1.4 8.4 11.8 1.6 8.3 11.8 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF3523 PF12037.8 CDJ45847.1 - 1.5 8.2 39.6 1.8 7.9 39.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) FAM60A PF15396.6 CDJ45847.1 - 1.5 8.8 18.7 1.8 8.5 18.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.9 CDJ45847.1 - 1.5 7.0 40.1 1.4 7.0 40.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Serinc PF03348.15 CDJ45847.1 - 1.6 7.6 12.2 1.9 7.3 12.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) GET2 PF08690.10 CDJ45847.1 - 2.2 7.9 21.2 2.5 7.7 21.2 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Spore_coat_CotO PF14153.6 CDJ45847.1 - 2.4 8.0 32.3 3.2 7.6 32.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Peroxin-3 PF04882.12 CDJ45847.1 - 2.8 6.8 22.7 3 6.7 22.7 1.1 1 0 0 1 1 1 0 Peroxin-3 Hamartin PF04388.12 CDJ45847.1 - 2.9 6.4 21.9 2.7 6.5 21.9 1.1 1 0 0 1 1 1 0 Hamartin protein Smg8_Smg9 PF10220.9 CDJ45847.1 - 3 6.0 23.0 3.4 5.9 23.0 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Lin-8 PF03353.15 CDJ45847.1 - 3.2 7.2 27.8 3.5 7.1 27.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3807 PF12720.7 CDJ45847.1 - 3.3 8.0 32.7 5.5 7.2 32.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF4045 PF13254.6 CDJ45847.1 - 3.4 7.2 26.3 3.5 7.2 26.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.14 CDJ45847.1 - 3.5 5.8 22.1 4.2 5.6 22.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2370 PF10176.9 CDJ45847.1 - 3.6 7.2 11.3 4.9 6.7 11.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Asp-B-Hydro_N PF05279.11 CDJ45847.1 - 3.7 7.5 17.6 4 7.5 17.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SAPS PF04499.15 CDJ45847.1 - 4 6.1 19.3 3.8 6.2 19.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2347 PF09804.9 CDJ45847.1 - 4 6.9 10.5 4.3 6.8 10.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Paramyxo_ncap PF00973.19 CDJ45847.1 - 4.9 6.0 20.3 5.5 5.8 20.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SLC12 PF03522.15 CDJ45847.1 - 5.2 6.0 27.1 5.8 5.8 27.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 HemX PF04375.14 CDJ45847.1 - 5.2 6.3 45.2 6.1 6.0 45.2 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase AMP-binding PF00501.28 CDJ45847.1 - 5.3 5.5 9.1 6.3 5.3 9.1 1.1 1 0 0 1 1 1 0 AMP-binding enzyme SelP_N PF04592.14 CDJ45847.1 - 5.9 6.2 23.9 7.8 5.8 23.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MAJIN PF15077.6 CDJ45847.1 - 6.5 6.5 18.7 7.8 6.2 18.7 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Activator_LAG-3 PF11498.8 CDJ45848.1 - 0.00066 18.8 19.1 0.00086 18.4 19.1 1.4 1 0 0 1 1 1 1 Transcriptional activator LAG-3 LMBR1 PF04791.16 CDJ45848.1 - 0.0019 17.2 4.6 0.0022 17.0 4.6 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein EFTUD2 PF16004.5 CDJ45848.1 - 0.016 15.8 8.1 0.027 15.0 8.1 1.5 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Stevor PF17410.2 CDJ45848.1 - 0.061 12.9 7.3 0.091 12.3 7.3 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4518 PF15008.6 CDJ45848.1 - 0.075 12.2 8.8 0.1 11.7 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) SOBP PF15279.6 CDJ45848.1 - 0.092 13.3 15.4 0.11 13.1 15.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein NPR3 PF03666.13 CDJ45848.1 - 0.11 11.3 15.8 0.14 11.0 15.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 CDJ45848.1 - 0.2 10.4 12.6 0.21 10.4 12.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SID-1_RNA_chan PF13965.6 CDJ45848.1 - 0.31 9.4 4.4 0.34 9.3 4.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 CDJ45848.1 - 0.42 8.9 17.2 0.64 8.2 17.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.11 CDJ45848.1 - 0.42 9.0 14.9 0.51 8.8 14.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 MCM_bind PF09739.9 CDJ45848.1 - 0.45 8.9 15.3 0.63 8.4 15.3 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SR-25 PF10500.9 CDJ45848.1 - 0.63 9.6 32.4 0.21 11.2 29.6 1.6 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4638 PF15472.6 CDJ45848.1 - 0.68 9.6 11.4 0.84 9.3 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) RLL PF10036.9 CDJ45848.1 - 1.2 8.9 19.0 1.8 8.3 19.0 1.3 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein DDRGK PF09756.9 CDJ45848.1 - 1.4 8.5 20.7 1.8 8.1 20.7 1.1 1 0 0 1 1 1 0 DDRGK domain eIF-3_zeta PF05091.12 CDJ45848.1 - 1.4 7.8 18.7 1.8 7.4 18.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spem1 PF15670.5 CDJ45848.1 - 1.7 8.2 16.8 2.5 7.6 16.8 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Bul1_N PF04425.12 CDJ45848.1 - 1.7 7.3 11.1 2.4 6.8 11.1 1.2 1 0 0 1 1 1 0 Bul1 N terminus PAT1 PF09770.9 CDJ45848.1 - 1.7 6.8 22.8 1.9 6.6 22.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nucleocapsid-N PF11030.8 CDJ45848.1 - 2 8.3 16.4 2.9 7.8 16.4 1.3 1 1 0 1 1 1 0 Nucleocapsid protein N Draxin PF15550.6 CDJ45848.1 - 2.1 8.1 16.6 3.3 7.5 16.6 1.3 1 0 0 1 1 1 0 Draxin Connexin PF00029.19 CDJ45848.1 - 2.4 7.8 9.7 3.3 7.4 9.7 1.3 1 0 0 1 1 1 0 Connexin Cellulose_synt PF03552.14 CDJ45848.1 - 2.6 6.4 4.8 3 6.2 4.8 1.1 1 0 0 1 1 1 0 Cellulose synthase EMC3_TMCO1 PF01956.16 CDJ45848.1 - 2.6 7.8 6.3 3.3 7.4 6.3 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SWI-SNF_Ssr4 PF08549.10 CDJ45848.1 - 3 6.4 32.0 3.8 6.0 32.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF2828 PF11443.8 CDJ45848.1 - 8.3 4.4 20.1 10 4.0 20.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) YbgS PF13985.6 CDJ45849.1 - 0.026 14.8 4.1 0.026 14.8 4.1 3.9 3 2 0 3 3 3 0 YbgS-like protein Ribosomal_60s PF00428.19 CDJ45849.1 - 0.037 14.6 9.5 0.037 14.6 9.5 5.8 5 1 0 5 5 5 0 60s Acidic ribosomal protein Pex14_N PF04695.13 CDJ45849.1 - 0.94 10.1 30.2 1.6 9.3 3.7 3.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4228 PF14009.6 CDJ45849.1 - 6.1 7.2 16.9 0.36 11.2 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4228) DUF1645 PF07816.11 CDJ45849.1 - 6.3 7.3 19.9 2.5 8.6 7.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) Apt1 PF10351.9 CDJ45849.1 - 9.4 5.0 13.0 0.17 10.7 0.2 2.8 3 0 0 3 3 3 0 Golgi-body localisation protein domain MAGE PF01454.19 CDJ45851.1 - 6.7 6.4 16.7 46 3.6 0.0 3.4 2 1 1 3 3 3 0 MAGE family BRF1 PF07741.13 CDJ45851.1 - 8 6.9 11.7 6.4 7.2 4.0 2.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Sporozoite_P67 PF05642.11 CDJ45853.1 - 0.28 9.2 14.0 0.34 9.0 14.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ctr PF04145.15 CDJ45853.1 - 1.8 9.1 3.7 2.8 8.5 3.7 1.5 1 0 0 1 1 1 0 Ctr copper transporter family PAT1 PF09770.9 CDJ45853.1 - 2.5 6.2 18.7 2.9 6.0 18.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF908 PF06012.12 CDJ45853.1 - 3 7.2 9.8 4.5 6.6 9.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Presenilin PF01080.17 CDJ45853.1 - 4.3 6.0 12.8 6.9 5.3 12.8 1.4 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 CDJ45853.1 - 4.5 6.7 6.9 5.5 6.4 6.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 SpoIIP PF07454.11 CDJ45853.1 - 6.7 6.1 10.4 8.2 5.8 10.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 CDJ45854.1 - 0.055 13.6 32.6 0.33 11.1 27.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 CDJ45854.1 - 0.064 12.0 44.1 0.26 10.0 36.1 2.0 2 0 0 2 2 2 0 Presenilin PRCH PF03967.13 CDJ45854.1 - 0.11 12.8 0.1 0.11 12.8 0.1 3.0 2 1 1 3 3 2 0 Photosynthetic reaction centre, H-chain N-terminal region MRP-S31 PF15433.6 CDJ45854.1 - 0.39 10.3 40.4 1.6 8.4 33.1 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 HEPN_Toprim_N PF18871.1 CDJ45854.1 - 0.88 9.5 6.5 1.4 8.8 6.5 1.3 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 DAG_kinase_N PF14513.6 CDJ45854.1 - 1.5 9.0 36.5 0.39 10.9 26.1 2.4 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus AAA_11 PF13086.6 CDJ45854.1 - 1.7 8.4 37.9 0.19 11.5 28.2 2.0 2 0 0 2 2 2 0 AAA domain Zip PF02535.22 CDJ45854.1 - 2.8 7.1 21.8 0.69 9.1 15.8 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter NARP1 PF12569.8 CDJ45854.1 - 3.1 6.6 41.5 0.41 9.5 30.4 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Isy1 PF06246.12 CDJ45854.1 - 7.6 6.0 38.6 0.92 9.0 27.7 2.1 2 0 0 2 2 2 0 Isy1-like splicing family SAPS PF04499.15 CDJ45854.1 - 8.1 5.1 28.1 14 4.3 28.1 1.3 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein Aldedh PF00171.22 CDJ45855.1 - 1.1e-136 456.1 5.3 4.3e-136 454.1 5.3 1.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family SUZ PF12752.7 CDJ45855.1 - 0.21 12.4 4.6 5 8.0 0.1 3.2 3 0 0 3 3 3 0 SUZ domain EBP50_C PF09007.11 CDJ45855.1 - 0.32 12.0 4.1 2 9.4 0.1 3.0 3 0 0 3 3 3 0 EBP50, C-terminal MACPF PF01823.19 CDJ45856.1 - 2.1e-30 106.4 0.0 3.6e-25 89.3 0.0 2.0 2 0 0 2 2 2 2 MAC/Perforin domain Spt20 PF12090.8 CDJ45857.1 - 0.0085 15.7 44.6 0.15 11.7 17.7 2.1 2 0 0 2 2 2 2 Spt20 family Pex14_N PF04695.13 CDJ45857.1 - 2.3 8.9 22.0 0.4 11.3 7.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.32 CDJ45859.1 - 2e-09 37.9 3.9 1.7 9.6 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ45859.1 - 0.074 13.4 0.0 1.8 8.9 0.0 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Mob1_phocein PF03637.17 CDJ45860.1 - 2.8e-10 40.5 0.5 2.8e-10 40.5 0.5 1.6 2 0 0 2 2 2 1 Mob1/phocein family Baculo_PP31 PF05311.11 CDJ45860.1 - 0.023 14.2 3.1 0.022 14.3 3.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF4834 PF16118.5 CDJ45860.1 - 0.029 15.3 5.5 0.036 15.0 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CPSF100_C PF13299.6 CDJ45860.1 - 0.029 14.5 4.9 0.036 14.2 4.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 CDJ45860.1 - 0.048 13.8 3.0 0.049 13.8 3.0 1.1 1 0 0 1 1 1 0 DDHD domain WASH-7_C PF14746.6 CDJ45860.1 - 0.06 13.0 6.9 0.071 12.8 6.9 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal RED_N PF07808.13 CDJ45860.1 - 0.091 12.3 12.4 0.12 11.9 12.4 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region CLN3 PF02487.17 CDJ45860.1 - 0.14 11.1 3.0 0.16 11.0 3.0 1.0 1 0 0 1 1 1 0 CLN3 protein Connexin PF00029.19 CDJ45860.1 - 0.18 11.5 3.9 0.2 11.4 3.9 1.1 1 0 0 1 1 1 0 Connexin Ctr PF04145.15 CDJ45860.1 - 0.2 12.2 1.4 0.21 12.2 1.4 1.2 1 0 0 1 1 1 0 Ctr copper transporter family SpoIIP PF07454.11 CDJ45860.1 - 0.31 10.4 8.1 0.36 10.2 8.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EOS1 PF12326.8 CDJ45860.1 - 0.42 10.5 1.9 0.41 10.6 1.9 1.1 1 0 0 1 1 1 0 N-glycosylation protein Kei1 PF08552.11 CDJ45860.1 - 0.52 10.2 2.2 0.52 10.2 2.2 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TFIIA PF03153.13 CDJ45860.1 - 0.73 9.8 21.3 0.76 9.7 21.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4746 PF15928.5 CDJ45860.1 - 0.98 8.8 8.1 1.1 8.6 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Orf78 PF06024.12 CDJ45860.1 - 1.1 9.6 3.8 1.5 9.1 3.8 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Coilin_N PF15862.5 CDJ45860.1 - 1.5 8.6 11.6 2.2 8.1 11.6 1.3 1 0 0 1 1 1 0 Coilin N-terminus EIIBC-GUT_N PF03612.14 CDJ45860.1 - 2.9 7.6 8.6 3.3 7.4 8.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 CDJ45860.1 - 3.5 6.3 11.2 3.9 6.1 11.2 1.1 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 CDJ45860.1 - 6.6 7.1 7.8 8.4 6.8 7.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Hus1 PF04005.12 CDJ45861.1 - 8.1e-13 48.1 0.1 2.8e-09 36.5 0.0 2.1 1 1 1 2 2 2 2 Hus1-like protein GCP_C_terminal PF04130.13 CDJ45862.1 - 3.5e-18 66.1 24.0 3.5e-18 66.1 24.0 3.0 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal DUF4667 PF15700.5 CDJ45862.1 - 0.025 14.7 0.2 0.025 14.7 0.2 8.5 7 3 1 8 8 8 0 Domain of unknown function (DUF4667) Sin_N PF04801.13 CDJ45862.1 - 2.8 7.1 0.0 0.034 13.4 5.0 6.9 5 2 1 6 6 6 0 Sin-like protein conserved region SR-25 PF10500.9 CDJ45863.1 - 0.062 12.9 18.7 0.072 12.7 18.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ45863.1 - 0.22 11.8 16.7 0.23 11.7 16.7 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Lin-8 PF03353.15 CDJ45863.1 - 0.28 10.7 7.4 0.27 10.7 7.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Herpes_pp85 PF04637.12 CDJ45863.1 - 2.3 6.5 6.9 2.8 6.2 6.9 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF1635 PF07795.11 CDJ45863.1 - 3.9 7.3 12.5 4.9 6.9 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Bclt PF15318.6 CDJ45863.1 - 4.7 7.0 10.0 6.9 6.5 9.6 1.3 1 1 0 1 1 1 0 Putative Bcl-2 like protein of testis Paf1 PF03985.13 CDJ45863.1 - 6.2 5.7 9.3 6.6 5.6 9.3 1.0 1 0 0 1 1 1 0 Paf1 SR-25 PF10500.9 CDJ45864.1 - 0.00014 21.6 31.0 0.0031 17.2 5.0 2.9 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein UPF0242 PF06785.11 CDJ45864.1 - 0.018 15.2 5.9 0.018 15.2 5.9 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PGA2 PF07543.12 CDJ45864.1 - 1.2 9.1 11.3 2.7 7.9 2.3 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Peptidase_S49_N PF08496.10 CDJ45864.1 - 1.5 8.9 10.1 0.24 11.4 1.3 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SpoIIP PF07454.11 CDJ45864.1 - 1.6 8.1 11.7 1.1 8.7 4.2 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) XRN_M PF17846.1 CDJ45864.1 - 3.2 6.6 6.0 7.2 5.4 2.1 2.0 2 0 0 2 2 2 0 Xrn1 helical domain BRF1 PF07741.13 CDJ45864.1 - 3.6 8.0 14.0 6.9 7.1 5.5 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain PPP4R2 PF09184.11 CDJ45864.1 - 3.7 7.0 8.8 1.1 8.8 4.1 2.0 2 0 0 2 2 2 0 PPP4R2 V_ATPase_I PF01496.19 CDJ45864.1 - 5.7 4.7 8.8 2.3 6.0 3.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SPX PF03105.19 CDJ45865.1 - 0.00074 19.6 18.9 0.00089 19.3 18.9 1.2 1 0 0 1 1 1 1 SPX domain LAP1C PF05609.12 CDJ45865.1 - 0.4 9.7 20.8 0.51 9.4 20.8 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Utp14 PF04615.13 CDJ45865.1 - 1 7.9 16.0 1.1 7.7 16.0 1.0 1 0 0 1 1 1 0 Utp14 protein PAP1 PF08601.10 CDJ45865.1 - 2.5 7.7 34.9 4 7.1 34.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 CSG2 PF16965.5 CDJ45865.1 - 3.1 6.6 6.5 2 7.3 2.9 1.9 1 1 1 2 2 2 0 Ceramide synthase regulator TFIIA PF03153.13 CDJ45865.1 - 10 6.0 29.6 17 5.2 29.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2370 PF10176.9 CDJ45866.1 - 4.4 6.9 15.2 1.6 8.3 1.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2370) Ribosomal_60s PF00428.19 CDJ45867.1 - 0.0068 17.0 12.6 0.0068 17.0 12.6 10.4 10 2 1 11 11 11 2 60s Acidic ribosomal protein RskA PF10099.9 CDJ45867.1 - 0.0095 16.3 5.7 0.0095 16.3 5.7 10.6 4 3 5 10 10 10 3 Anti-sigma-K factor rskA Dscam_C PF12355.8 CDJ45867.1 - 0.19 12.7 10.4 0.51 11.3 0.9 2.9 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal PBECR5 PF18814.1 CDJ45867.1 - 0.88 9.5 14.1 0.021 14.8 5.5 2.4 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 zf-C2H2_4 PF13894.6 CDJ45869.1 - 0.023 15.5 0.3 0.15 13.0 0.3 2.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ45869.1 - 0.22 11.9 0.0 0.22 11.9 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SR-25 PF10500.9 CDJ45871.1 - 0.015 14.9 4.5 0.015 14.9 4.5 2.7 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ45871.1 - 0.043 14.1 29.9 0.13 12.6 12.3 3.0 2 1 1 3 3 3 0 Early growth response N-terminal domain SPX PF03105.19 CDJ45871.1 - 0.13 12.2 6.1 0.15 12.0 6.1 1.2 1 0 0 1 1 1 0 SPX domain IMUP PF15761.5 CDJ45871.1 - 0.53 11.0 24.6 0.23 12.1 3.5 2.7 3 0 0 3 3 3 0 Immortalisation up-regulated protein ATP-synt_ab PF00006.25 CDJ45872.1 - 1.5e-65 220.9 0.0 2.2e-65 220.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDJ45872.1 - 6.7e-06 26.5 0.9 0.0051 17.3 0.1 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, beta-barrel domain EPSP_synthase PF00275.20 CDJ45874.1 - 3.7e-06 25.9 2.2 0.0022 16.7 0.1 2.9 3 0 0 3 3 3 2 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) TMEM208_SND2 PF05620.11 CDJ45874.1 - 0.00025 20.9 1.5 0.00025 20.9 1.5 3.7 3 2 2 5 5 5 1 SRP-independent targeting protein 2/TMEM208 CBP_BcsG PF11658.8 CDJ45874.1 - 2 6.7 20.1 0.039 12.4 9.7 2.6 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsG Shikimate_dh_N PF08501.11 CDJ45875.1 - 0.0011 19.2 1.1 0.044 14.0 0.0 3.6 3 0 0 3 3 3 1 Shikimate dehydrogenase substrate binding domain SR-25 PF10500.9 CDJ45876.1 - 3.5e-05 23.5 23.7 0.0012 18.5 6.1 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein EPSP_synthase PF00275.20 CDJ45876.1 - 0.00025 19.9 2.9 0.00034 19.4 0.0 2.3 2 1 0 2 2 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) IMUP PF15761.5 CDJ45876.1 - 0.002 18.8 28.4 0.0064 17.2 5.0 2.4 2 0 0 2 2 2 2 Immortalisation up-regulated protein DUF4667 PF15700.5 CDJ45876.1 - 0.0066 16.6 12.3 0.14 12.2 1.9 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) DUF1645 PF07816.11 CDJ45876.1 - 0.047 14.3 13.3 0.63 10.6 3.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Apt1 PF10351.9 CDJ45876.1 - 0.15 10.9 2.2 0.2 10.5 2.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.15 CDJ45876.1 - 0.99 8.9 6.2 1.5 8.3 1.6 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Rotamase_2 PF13145.6 CDJ45876.1 - 1.2 10.0 15.5 4.1 8.3 9.1 2.2 2 0 0 2 2 2 0 PPIC-type PPIASE domain DUF4692 PF15763.5 CDJ45876.1 - 1.5 9.2 14.5 2.4 8.6 3.6 2.1 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) RIFIN PF02009.16 CDJ45876.1 - 1.7 8.5 6.7 2.1 8.1 6.7 1.2 1 0 0 1 1 1 0 Rifin SUZ PF12752.7 CDJ45876.1 - 2.7 8.8 8.3 2.4 9.0 0.4 2.6 2 0 0 2 2 2 0 SUZ domain Secretin_N_2 PF07655.13 CDJ45876.1 - 5 7.7 15.8 10 6.7 5.0 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain CCDC106 PF15794.5 CDJ45876.1 - 6.4 6.4 11.3 1.8 8.2 2.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 SRP-alpha_N PF04086.13 CDJ45878.1 - 0.0033 17.4 8.0 0.0036 17.3 8.0 1.0 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Pex14_N PF04695.13 CDJ45878.1 - 0.0042 17.8 12.0 0.0052 17.4 12.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ45878.1 - 0.0068 16.0 16.0 0.0068 16.0 16.0 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ45878.1 - 0.018 14.0 12.8 0.018 14.0 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Mcm10 PF09332.11 CDJ45878.1 - 0.028 13.9 9.2 0.033 13.6 9.2 1.0 1 0 0 1 1 1 0 Mcm10 replication factor Herpes_UL74 PF07982.12 CDJ45878.1 - 0.034 13.1 0.9 0.04 12.9 0.9 1.1 1 0 0 1 1 1 0 Herpes UL74 glycoproteins DUF4813 PF16072.5 CDJ45878.1 - 0.069 12.8 11.1 0.078 12.6 11.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) TFIIA PF03153.13 CDJ45878.1 - 0.11 12.4 20.2 0.12 12.4 20.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MPM1 PF17234.2 CDJ45878.1 - 0.15 12.3 6.8 0.16 12.2 6.8 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Sarcoglycan_2 PF05510.13 CDJ45878.1 - 0.23 10.2 2.6 0.24 10.1 2.6 1.0 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Hist_deacetyl PF00850.19 CDJ45878.1 - 0.59 9.5 3.7 0.72 9.3 3.7 1.1 1 0 0 1 1 1 0 Histone deacetylase domain XRN_M PF17846.1 CDJ45878.1 - 0.89 8.4 8.7 1.1 8.2 8.7 1.0 1 0 0 1 1 1 0 Xrn1 helical domain TERB2 PF15101.6 CDJ45878.1 - 1.1 9.2 9.4 1.2 9.1 9.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 BAF1_ABF1 PF04684.13 CDJ45878.1 - 1.2 8.1 12.6 1.3 8.0 12.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MAGE PF01454.19 CDJ45878.1 - 1.5 8.5 7.8 1.6 8.4 7.8 1.1 1 0 0 1 1 1 0 MAGE family Herpes_DNAp_acc PF04929.12 CDJ45878.1 - 1.5 7.7 6.0 1.5 7.7 6.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor UPF0560 PF10577.9 CDJ45878.1 - 1.7 7.1 9.8 1.9 6.9 9.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 ALMT PF11744.8 CDJ45878.1 - 2.7 6.7 5.9 2.8 6.7 5.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CLN3 PF02487.17 CDJ45878.1 - 2.8 6.9 4.5 2.8 6.9 4.5 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4834 PF16118.5 CDJ45878.1 - 3.3 8.7 9.6 4.7 8.2 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RIFIN PF02009.16 CDJ45878.1 - 3.5 7.4 9.3 4.2 7.2 9.3 1.1 1 0 0 1 1 1 0 Rifin DUF2368 PF10166.9 CDJ45878.1 - 4 7.1 12.7 4.6 6.9 12.7 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Roughex PF06020.11 CDJ45878.1 - 4.4 6.3 10.1 4.9 6.2 10.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Neur_chan_memb PF02932.16 CDJ45878.1 - 4.9 7.1 5.5 5.5 7.0 5.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ45878.1 - 7.9 5.1 11.9 8.4 5.0 11.9 1.0 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ45879.1 - 0.0015 17.6 0.6 0.0015 17.6 0.6 4.6 3 1 0 3 3 3 1 Protein of unknown function (DUF2722) Lin-8 PF03353.15 CDJ45879.1 - 0.0041 16.7 24.7 0.073 12.6 1.5 2.4 2 0 0 2 2 2 2 Ras-mediated vulval-induction antagonist Pox_P4B PF03292.14 CDJ45879.1 - 0.64 8.2 2.4 1.6 6.9 2.4 1.6 1 0 0 1 1 1 0 Poxvirus P4B major core protein SLC12 PF03522.15 CDJ45879.1 - 3.2 6.7 20.6 0.99 8.4 2.8 2.2 2 0 0 2 2 2 0 Solute carrier family 12 XAP5 PF04921.14 CDJ45879.1 - 5.8 6.7 14.7 1.8 8.3 5.3 2.5 2 0 0 2 2 2 0 XAP5, circadian clock regulator GPCR_chapero_1 PF11904.8 CDJ45879.1 - 8.9 5.6 10.4 13 5.1 0.5 2.4 2 0 0 2 2 2 0 GPCR-chaperone Histone PF00125.24 CDJ45880.1 - 6.6e-18 65.3 0.1 6.6e-18 65.3 0.1 3.5 1 1 2 3 3 3 1 Core histone H2A/H2B/H3/H4 Hamartin PF04388.12 CDJ45880.1 - 3.4 6.2 42.9 4.7 5.7 42.9 1.1 1 0 0 1 1 1 0 Hamartin protein CRA PF06589.11 CDJ45881.1 - 3 7.9 6.1 0.49 10.5 0.5 2.3 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) DUF4964 PF16334.5 CDJ45882.1 - 0.0032 17.0 0.2 0.005 16.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) DDHD PF02862.17 CDJ45882.1 - 0.0054 16.9 4.1 0.007 16.5 4.1 1.1 1 0 0 1 1 1 1 DDHD domain Gaa1 PF04114.14 CDJ45882.1 - 0.062 12.3 0.7 0.065 12.3 0.7 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component TFIIA PF03153.13 CDJ45882.1 - 0.082 12.9 26.6 0.097 12.6 26.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Prim-Pol PF09250.11 CDJ45882.1 - 0.13 12.6 3.4 0.57 10.5 1.0 2.0 1 1 1 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal DUF1822 PF08852.11 CDJ45882.1 - 0.26 10.3 17.5 0.3 10.1 17.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) DUF4518 PF15008.6 CDJ45882.1 - 0.29 10.3 8.5 0.34 10.0 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) SARAF PF06682.12 CDJ45882.1 - 0.29 10.7 7.9 0.38 10.4 7.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Hid1 PF12722.7 CDJ45882.1 - 0.36 8.9 6.2 0.39 8.8 6.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ctr PF04145.15 CDJ45882.1 - 0.55 10.9 7.5 0.73 10.4 7.5 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF3292 PF11696.8 CDJ45882.1 - 0.56 8.5 7.6 0.68 8.2 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) MDM10 PF12519.8 CDJ45882.1 - 0.57 9.0 4.5 0.63 8.8 4.5 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Pex14_N PF04695.13 CDJ45882.1 - 0.63 10.7 22.4 1 10.0 22.4 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5349 PF17298.2 CDJ45882.1 - 0.96 9.1 10.2 1.2 8.9 10.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF775 PF05603.12 CDJ45882.1 - 1.3 8.5 9.6 1.8 8.1 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Presenilin PF01080.17 CDJ45882.1 - 1.5 7.5 9.0 1.6 7.4 9.0 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 CDJ45882.1 - 1.5 7.5 5.6 1.7 7.4 5.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ45882.1 - 3.2 5.9 22.0 3.6 5.7 22.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2371 PF10177.9 CDJ45882.1 - 4 7.6 4.6 22 5.2 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF3464 PF11947.8 CDJ45882.1 - 4.2 7.1 9.9 2.3 8.0 6.3 1.9 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 CLN3 PF02487.17 CDJ45882.1 - 5.7 5.9 5.8 6.5 5.7 5.8 1.2 1 0 0 1 1 1 0 CLN3 protein UQ_con PF00179.26 CDJ45884.1 - 3.3e-44 149.9 0.0 3.7e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ45884.1 - 0.0035 17.0 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CDJ45884.1 - 0.0062 16.4 0.1 0.011 15.6 0.1 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 CDJ45884.1 - 0.16 12.2 0.3 0.25 11.6 0.2 1.4 1 1 0 1 1 1 0 RWD domain BaxI_1 PF12811.7 CDJ45885.1 - 0.45 10.0 7.0 0.069 12.7 3.4 1.5 2 0 0 2 2 2 0 Bax inhibitor 1 like ICMT PF04140.14 CDJ45886.1 - 0.0053 17.2 1.1 0.016 15.6 0.1 2.4 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family SPX PF03105.19 CDJ45886.1 - 0.01 15.8 11.1 2.2 8.1 12.8 2.8 2 1 0 2 2 2 0 SPX domain RskA PF10099.9 CDJ45886.1 - 0.049 13.9 54.1 0.036 14.4 4.2 4.9 2 2 3 5 5 5 0 Anti-sigma-K factor rskA Myosin_head PF00063.21 CDJ45888.1 - 6.5e-188 626.1 0.2 7.7e-188 625.9 0.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CDJ45888.1 - 0.022 15.1 0.3 0.084 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PRK PF00485.18 CDJ45888.1 - 0.14 11.9 0.1 1.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Exonuc_VII_L PF02601.15 CDJ45889.1 - 0.04 13.5 0.0 0.04 13.5 0.0 6.3 1 1 2 3 3 3 0 Exonuclease VII, large subunit HA2 PF04408.23 CDJ45890.1 - 6.5e-22 77.9 0.1 6.5e-22 77.9 0.1 8.9 8 1 0 8 8 8 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ45890.1 - 4.4e-19 68.6 0.1 1.6e-18 66.8 0.1 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold SR-25 PF10500.9 CDJ45890.1 - 0.00049 19.8 21.3 0.00049 19.8 21.3 12.2 11 2 2 13 13 13 3 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 CDJ45890.1 - 0.00055 19.4 14.3 0.00055 19.4 14.3 7.0 5 2 0 5 5 5 1 BUD22 SARAF PF06682.12 CDJ45890.1 - 0.0057 16.3 4.4 0.0057 16.3 4.4 8.3 8 1 0 8 8 8 2 SOCE-associated regulatory factor of calcium homoeostasis Nucleoside_tran PF01733.18 CDJ45891.1 - 1.6e-23 83.5 4.8 3.4e-22 79.2 0.1 2.4 2 0 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 CDJ45891.1 - 0.0024 16.8 3.9 0.0024 16.8 3.9 3.6 1 1 1 2 2 1 1 Major Facilitator Superfamily DUF4407 PF14362.6 CDJ45891.1 - 0.013 14.8 0.4 0.013 14.8 0.4 2.3 2 0 0 2 2 1 0 Domain of unknown function (DUF4407) Suf PF05843.14 CDJ45891.1 - 0.038 14.0 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ45891.1 - 0.082 11.7 1.0 0.26 10.0 1.0 1.9 1 0 0 1 1 1 0 Presenilin bMG10 PF17973.1 CDJ45891.1 - 0.097 12.9 0.7 0.18 12.0 0.7 1.4 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain Eapp_C PF10238.9 CDJ45891.1 - 0.13 12.4 1.2 0.22 11.6 1.2 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein PAT1 PF09770.9 CDJ45891.1 - 0.36 9.1 8.0 0.51 8.6 8.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RPN2_C PF18004.1 CDJ45891.1 - 0.7 9.8 5.2 1.1 9.2 5.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4820 PF16091.5 CDJ45891.1 - 1.2 8.5 4.1 2 7.7 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4633 PF15464.6 CDJ45891.1 - 1.3 9.2 10.3 2.3 8.4 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) eIF-3_zeta PF05091.12 CDJ45891.1 - 6.2 5.7 7.3 8 5.3 7.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4746 PF15928.5 CDJ45891.1 - 7.6 5.9 5.5 11 5.3 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1674 PF07896.12 CDJ45892.1 - 8 7.0 9.2 0.86 10.1 3.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1674) Mucin-like PF16058.5 CDJ45893.1 - 3.6e-06 27.0 21.4 3.6e-06 27.0 21.4 2.7 3 0 0 3 3 1 1 Mucin-like UbiA PF01040.18 CDJ45893.1 - 0.0015 17.9 9.1 0.0015 17.9 9.1 3.0 2 1 1 3 3 3 1 UbiA prenyltransferase family Connexin PF00029.19 CDJ45893.1 - 0.0064 16.3 0.7 0.034 13.9 0.1 1.9 2 0 0 2 2 2 1 Connexin RskA PF10099.9 CDJ45893.1 - 0.013 15.8 14.6 0.013 15.8 14.6 3.6 3 1 0 3 3 2 0 Anti-sigma-K factor rskA DUF4366 PF14283.6 CDJ45893.1 - 0.049 13.7 0.5 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF2956 PF11169.8 CDJ45893.1 - 0.2 11.9 7.6 1.5 9.1 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Orf78 PF06024.12 CDJ45893.1 - 0.27 11.6 0.2 20 5.6 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) DUF4179 PF13786.6 CDJ45893.1 - 0.3 11.6 2.9 16 6.0 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) TFIIA PF03153.13 CDJ45893.1 - 0.49 10.3 23.5 0.53 10.2 5.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 CDJ45893.1 - 0.82 9.0 27.2 0.027 13.9 20.7 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF5345 PF17280.2 CDJ45893.1 - 0.93 9.5 6.0 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Suf PF05843.14 CDJ45893.1 - 2.6 7.9 6.4 6.8 6.6 0.6 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Allantoicase PF03561.15 CDJ45893.1 - 3.2 7.7 6.4 17 5.4 0.2 2.1 2 0 0 2 2 2 0 Allantoicase repeat FHIPEP PF00771.20 CDJ45893.1 - 6.8 5.0 6.0 11 4.4 1.6 2.0 2 0 0 2 2 2 0 FHIPEP family Spt20 PF12090.8 CDJ45893.1 - 8.8 5.9 18.7 0.15 11.6 0.8 2.2 2 0 0 2 2 2 0 Spt20 family VRR_NUC PF08774.11 CDJ45894.1 - 1.8e-16 60.1 7.5 2.3e-13 50.1 7.5 3.9 1 1 0 1 1 1 1 VRR-NUC domain PAP1 PF08601.10 CDJ45894.1 - 0.0037 17.1 0.9 0.0037 17.1 0.9 10.9 8 3 3 12 12 12 1 Transcription factor PAP1 TMEM51 PF15345.6 CDJ45895.1 - 0.015 15.1 1.6 0.015 15.1 1.6 5.0 3 2 0 3 3 3 0 Transmembrane protein 51 MPM1 PF17234.2 CDJ45895.1 - 0.033 14.5 1.8 0.033 14.5 1.8 4.7 3 2 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 RskA PF10099.9 CDJ45897.1 - 0.00019 21.8 19.8 0.00019 21.8 19.8 13.5 2 2 5 9 9 9 2 Anti-sigma-K factor rskA ABC_export PF16962.5 CDJ45897.1 - 0.0016 17.0 0.0 0.0052 15.3 0.0 1.9 1 0 0 1 1 1 1 Putative ABC exporter Cytochrom_B_N_2 PF13631.6 CDJ45897.1 - 1.9 8.4 5.2 0.91 9.5 0.2 3.1 3 0 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB TFIIA PF03153.13 CDJ45898.1 - 0.043 13.8 43.0 0.052 13.6 43.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EMC3_TMCO1 PF01956.16 CDJ45898.1 - 0.19 11.4 3.6 0.22 11.2 3.6 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like HemX PF04375.14 CDJ45898.1 - 0.38 10.0 23.1 0.45 9.8 23.1 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Connexin PF00029.19 CDJ45898.1 - 0.58 9.9 10.8 0.75 9.5 10.8 1.4 1 0 0 1 1 1 0 Connexin PAT1 PF09770.9 CDJ45898.1 - 1.2 7.4 32.3 1.3 7.2 32.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1846 PF08903.11 CDJ45898.1 - 1.6 7.2 10.0 1.9 6.9 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) DUF4175 PF13779.6 CDJ45898.1 - 2.1 6.2 26.9 2.4 5.9 26.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2052 PF09747.9 CDJ45898.1 - 2.1 8.4 17.8 2.6 8.1 17.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4407 PF14362.6 CDJ45898.1 - 2.8 7.2 11.3 3.4 7.0 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 CDJ45898.1 - 3.3 6.6 20.4 3.9 6.3 20.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARP1 PF12569.8 CDJ45898.1 - 4.6 6.0 14.8 6.1 5.6 14.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4638 PF15472.6 CDJ45898.1 - 5.9 6.5 18.4 7 6.3 18.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Draxin PF15550.6 CDJ45898.1 - 6.3 6.6 19.7 8.1 6.2 19.7 1.2 1 0 0 1 1 1 0 Draxin PQQ PF01011.21 CDJ45899.1 - 9.1e-06 25.4 0.4 0.098 12.6 0.0 3.6 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_2 PF13360.6 CDJ45899.1 - 1.6e-05 24.6 14.6 1.6e-05 24.6 14.6 3.2 3 1 0 3 3 3 1 PQQ-like domain Spt20 PF12090.8 CDJ45899.1 - 0.063 12.9 60.9 0.1 12.2 3.8 5.0 5 0 0 5 5 5 0 Spt20 family SPRY PF00622.28 CDJ45899.1 - 2.6 8.2 9.8 0.37 10.9 3.2 2.5 2 0 0 2 2 2 0 SPRY domain AF-4 PF05110.13 CDJ45900.1 - 0.0034 15.6 25.9 0.0034 15.6 25.9 5.8 3 1 2 5 5 5 2 AF-4 proto-oncoprotein Sec66 PF09802.9 CDJ45901.1 - 5.9e-08 32.5 11.6 5.9e-08 32.5 11.6 2.3 1 1 1 2 2 2 1 Preprotein translocase subunit Sec66 CCSAP PF15748.5 CDJ45901.1 - 0.28 11.3 37.9 0.039 14.1 26.7 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Lin-8 PF03353.15 CDJ45901.1 - 0.88 9.1 42.7 1.3 8.5 31.3 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Hamartin PF04388.12 CDJ45901.1 - 5.6 5.5 34.8 7.2 5.1 34.8 1.2 1 0 0 1 1 1 0 Hamartin protein DUF2339 PF10101.9 CDJ45902.1 - 5.4 5.5 50.6 6.9 5.1 50.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) PseudoU_synth_1 PF01416.20 CDJ45904.1 - 0.0019 18.6 0.1 0.014 15.8 0.3 4.1 5 1 0 5 5 5 2 tRNA pseudouridine synthase Roughex PF06020.11 CDJ45904.1 - 0.0021 17.3 0.6 0.0021 17.3 0.6 6.3 5 1 1 6 6 6 2 Drosophila roughex protein DUF4179 PF13786.6 CDJ45904.1 - 5.5 7.5 0.0 5.5 7.5 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4179) Trp_oprn_chp PF09534.10 CDJ45904.1 - 6.6 6.5 36.5 0.1 12.4 5.9 4.9 5 0 0 5 5 5 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) eIF3_subunit PF08597.10 CDJ45905.1 - 0.0088 16.0 2.7 0.0088 16.0 2.7 8.0 6 2 1 7 7 7 1 Translation initiation factor eIF3 subunit RNA_pol_Rpc4 PF05132.14 CDJ45908.1 - 0.0014 19.1 5.9 0.0014 19.1 5.9 1.1 1 0 0 1 1 1 1 RNA polymerase III RPC4 Tim54 PF11711.8 CDJ45908.1 - 0.0026 16.6 8.5 0.0029 16.5 8.5 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 CDJ45908.1 - 0.0034 17.2 7.9 0.004 16.9 7.9 1.1 1 0 0 1 1 1 1 Connexin DUF5308 PF17233.2 CDJ45908.1 - 0.0049 17.1 7.9 0.0058 16.9 7.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5308) SpoIIP PF07454.11 CDJ45908.1 - 0.0083 15.6 13.1 0.0093 15.5 13.1 1.0 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DUF2828 PF11443.8 CDJ45908.1 - 0.0084 14.2 10.7 0.0088 14.2 10.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DDHD PF02862.17 CDJ45908.1 - 0.0097 16.1 9.3 0.01 16.0 9.3 1.1 1 0 0 1 1 1 1 DDHD domain CLN3 PF02487.17 CDJ45908.1 - 0.01 14.9 9.8 0.012 14.7 9.8 1.0 1 0 0 1 1 1 0 CLN3 protein OATP PF03137.20 CDJ45908.1 - 0.011 14.0 5.3 0.013 13.8 5.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family BAF1_ABF1 PF04684.13 CDJ45908.1 - 0.017 14.2 14.1 0.02 14.0 14.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3402 PF11882.8 CDJ45908.1 - 0.02 14.0 9.3 0.024 13.8 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) DUF913 PF06025.12 CDJ45908.1 - 0.023 13.7 8.0 0.024 13.6 8.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3464 PF11947.8 CDJ45908.1 - 0.027 14.2 11.2 0.038 13.7 11.2 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 AIF_C PF14721.6 CDJ45908.1 - 0.034 14.5 7.9 0.048 14.0 7.9 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FAM60A PF15396.6 CDJ45908.1 - 0.046 13.7 12.7 0.057 13.4 12.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RXT2_N PF08595.11 CDJ45908.1 - 0.048 13.7 9.9 0.06 13.4 9.9 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4228 PF14009.6 CDJ45908.1 - 0.049 14.0 5.3 0.055 13.9 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) EPL1 PF10513.9 CDJ45908.1 - 0.056 13.8 13.4 0.068 13.5 13.4 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like AF-4 PF05110.13 CDJ45908.1 - 0.067 11.3 16.5 0.073 11.2 16.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2126 PF09899.9 CDJ45908.1 - 0.07 11.2 9.2 0.077 11.1 9.2 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RP-C_C PF11800.8 CDJ45908.1 - 0.085 12.9 13.4 0.1 12.7 13.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Gastrin PF00918.17 CDJ45908.1 - 0.14 13.1 10.2 0.16 12.9 10.2 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family RabGAP-TBC PF00566.18 CDJ45908.1 - 0.14 11.8 15.2 0.17 11.5 15.2 1.0 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Zip PF02535.22 CDJ45908.1 - 0.2 10.9 8.3 0.22 10.7 8.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BORG_CEP PF14957.6 CDJ45908.1 - 0.2 12.8 9.1 0.24 12.6 9.1 1.1 1 0 0 1 1 1 0 Cdc42 effector LAP1C PF05609.12 CDJ45908.1 - 0.26 10.3 14.4 0.28 10.2 14.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4407 PF14362.6 CDJ45908.1 - 0.27 10.6 15.4 0.3 10.4 15.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PepSY_TM PF03929.16 CDJ45908.1 - 0.28 10.8 4.5 0.31 10.6 4.5 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Band_3_cyto PF07565.13 CDJ45908.1 - 0.28 11.0 13.7 0.31 10.8 13.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DNApol_Exo PF18136.1 CDJ45908.1 - 0.29 10.2 10.1 0.38 9.9 10.1 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain CSG2 PF16965.5 CDJ45908.1 - 0.29 10.0 7.1 0.32 9.9 7.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Endostatin PF06482.11 CDJ45908.1 - 0.3 10.5 13.7 0.34 10.4 13.7 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF5523 PF17661.1 CDJ45908.1 - 0.3 10.7 15.3 0.36 10.5 15.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Pex14_N PF04695.13 CDJ45908.1 - 0.3 11.7 26.0 0.38 11.4 26.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Patched PF02460.18 CDJ45908.1 - 0.34 8.9 3.8 0.39 8.7 3.8 1.0 1 0 0 1 1 1 0 Patched family DUF4050 PF13259.6 CDJ45908.1 - 0.36 11.1 14.6 0.45 10.8 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Eapp_C PF10238.9 CDJ45908.1 - 0.38 10.8 19.6 0.52 10.4 19.6 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein MCM_bind PF09739.9 CDJ45908.1 - 0.39 9.1 13.3 0.45 8.9 13.3 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Velvet PF11754.8 CDJ45908.1 - 0.53 10.2 16.7 0.63 9.9 16.7 1.0 1 0 0 1 1 1 0 Velvet factor Afi1 PF07792.12 CDJ45908.1 - 0.54 10.7 16.1 0.71 10.3 16.1 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 CDJ45908.1 - 0.54 9.0 21.7 0.65 8.7 21.7 1.0 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 CDJ45908.1 - 0.55 9.6 13.9 0.78 9.1 13.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3408 PF11888.8 CDJ45908.1 - 0.58 10.3 16.2 0.82 9.8 16.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Neur_chan_memb PF02932.16 CDJ45908.1 - 0.59 10.1 13.4 0.71 9.9 13.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.6 CDJ45908.1 - 0.61 10.2 13.9 0.79 9.9 13.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GREB1 PF15782.5 CDJ45908.1 - 0.76 6.8 14.2 0.8 6.8 14.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Gti1_Pac2 PF09729.9 CDJ45908.1 - 0.77 9.8 14.5 0.89 9.6 14.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Saw1 PF11561.8 CDJ45908.1 - 0.79 9.2 10.3 0.95 8.9 10.3 1.0 1 0 0 1 1 1 0 Single strand annealing-weakened 1 DUF2370 PF10176.9 CDJ45908.1 - 0.89 9.2 6.5 1 9.0 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) RR_TM4-6 PF06459.12 CDJ45908.1 - 1.1 9.0 19.8 1.3 8.8 19.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Membralin PF09746.9 CDJ45908.1 - 1.2 8.1 9.4 1.3 8.0 9.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein EOS1 PF12326.8 CDJ45908.1 - 1.3 8.9 9.3 1.7 8.5 9.3 1.2 1 0 0 1 1 1 0 N-glycosylation protein UPF0560 PF10577.9 CDJ45908.1 - 1.3 7.4 22.4 1.5 7.2 22.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 HCO3_cotransp PF00955.21 CDJ45908.1 - 1.4 7.7 9.1 1.6 7.4 9.1 1.0 1 0 0 1 1 1 0 HCO3- transporter family NARP1 PF12569.8 CDJ45908.1 - 1.4 7.8 16.7 1.6 7.5 16.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Scs3p PF10261.9 CDJ45908.1 - 1.5 8.2 3.8 1.9 8.0 3.8 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM CCDC53 PF10152.9 CDJ45908.1 - 1.6 9.2 18.5 1.8 8.9 18.5 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FAM176 PF14851.6 CDJ45908.1 - 1.6 8.4 10.8 2.1 8.0 10.8 1.2 1 0 0 1 1 1 0 FAM176 family PAT1 PF09770.9 CDJ45908.1 - 1.7 6.8 29.3 2 6.6 29.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SelP_N PF04592.14 CDJ45908.1 - 1.8 7.9 21.5 2.3 7.6 21.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SAPS PF04499.15 CDJ45908.1 - 2.1 7.0 13.4 2.4 6.8 13.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ureide_permease PF07168.11 CDJ45908.1 - 2.3 6.9 9.1 2.7 6.6 9.1 1.0 1 0 0 1 1 1 0 Ureide permease eIF3_subunit PF08597.10 CDJ45908.1 - 2.3 8.1 21.1 2.8 7.8 21.1 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Folate_carrier PF01770.18 CDJ45908.1 - 2.3 6.8 7.7 2.7 6.6 7.7 1.1 1 0 0 1 1 1 0 Reduced folate carrier CobT PF06213.12 CDJ45908.1 - 2.7 7.3 27.7 3.3 7.0 27.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ctr PF04145.15 CDJ45908.1 - 2.7 8.6 9.8 3.3 8.3 9.8 1.2 1 0 0 1 1 1 0 Ctr copper transporter family SLC12 PF03522.15 CDJ45908.1 - 2.7 6.9 18.0 3.1 6.7 18.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 ABC2_membrane_2 PF12679.7 CDJ45908.1 - 2.8 7.2 3.3 3.2 7.0 3.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Otopetrin PF03189.13 CDJ45908.1 - 2.8 6.7 11.1 3.1 6.5 11.1 1.0 1 0 0 1 1 1 0 Otopetrin LMBR1 PF04791.16 CDJ45908.1 - 4.1 6.2 10.2 4.7 6.0 10.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein PPL5 PF18168.1 CDJ45908.1 - 4.2 6.6 13.6 4.8 6.4 13.6 1.0 1 0 0 1 1 1 0 Prim-pol family 5 BPL_N PF09825.9 CDJ45908.1 - 4.2 6.3 9.3 5.2 6.1 9.3 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF2058 PF09831.9 CDJ45908.1 - 4.3 7.5 32.5 5 7.2 32.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Lin-8 PF03353.15 CDJ45908.1 - 4.3 6.8 20.8 4.9 6.6 20.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FliP PF00813.20 CDJ45908.1 - 4.6 7.1 6.2 4.9 7.0 6.2 1.1 1 0 0 1 1 1 0 FliP family eIF-3_zeta PF05091.12 CDJ45908.1 - 4.6 6.1 25.6 5.5 5.8 25.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Nucleoside_tran PF01733.18 CDJ45908.1 - 4.9 6.4 5.3 5.4 6.3 5.3 1.1 1 0 0 1 1 1 0 Nucleoside transporter V_ATPase_I PF01496.19 CDJ45908.1 - 5 4.9 21.1 5.9 4.7 21.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ45908.1 - 5.1 7.0 43.6 5.9 6.8 43.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4746 PF15928.5 CDJ45908.1 - 5.3 6.4 13.2 6.4 6.1 13.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NST1 PF13945.6 CDJ45908.1 - 5.3 7.1 26.4 6.7 6.8 26.4 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF5427 PF10310.9 CDJ45908.1 - 5.4 5.9 21.4 6.2 5.7 21.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CDC45 PF02724.14 CDJ45908.1 - 5.8 5.1 18.4 7.1 4.8 18.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Pal1 PF08316.11 CDJ45908.1 - 5.9 7.7 10.0 7.6 7.3 10.0 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Dicty_REP PF05086.12 CDJ45908.1 - 6.2 4.7 9.7 6.7 4.6 9.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PTPRCAP PF15713.5 CDJ45908.1 - 6.4 7.1 19.6 8.2 6.7 19.6 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Hid1 PF12722.7 CDJ45908.1 - 6.6 4.7 18.0 7.7 4.5 18.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_U57 PF05582.12 CDJ45908.1 - 6.7 5.9 13.8 8.8 5.5 13.8 1.1 1 0 0 1 1 1 0 YabG peptidase U57 EFTUD2 PF16004.5 CDJ45908.1 - 7.2 7.2 20.6 9.5 6.8 20.6 1.1 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus STAC2_u1 PF16664.5 CDJ45908.1 - 7.7 7.0 13.9 11 6.5 13.9 1.1 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 PRC2_HTH_1 PF18118.1 CDJ45908.1 - 7.7 7.4 13.4 11 6.9 13.4 1.3 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain PEHE PF15275.6 CDJ45908.1 - 8.4 7.0 18.5 11 6.7 18.5 1.2 1 0 0 1 1 1 0 PEHE domain MMM1 PF10296.9 CDJ45908.1 - 8.5 5.3 14.8 9.9 5.1 14.8 1.0 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 TERB2 PF15101.6 CDJ45908.1 - 8.5 6.4 25.0 11 6.0 25.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NPR3 PF03666.13 CDJ45908.1 - 8.6 5.0 18.4 10 4.8 18.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ALMT PF11744.8 CDJ45908.1 - 8.7 5.0 15.3 10 4.8 15.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SID-1_RNA_chan PF13965.6 CDJ45908.1 - 8.8 4.6 11.2 9.8 4.4 11.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MMU163 PF17119.5 CDJ45908.1 - 9 5.4 9.4 11 5.0 9.4 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Cellulose_synt PF03552.14 CDJ45908.1 - 9.8 4.5 7.1 11 4.4 7.1 1.0 1 0 0 1 1 1 0 Cellulose synthase MAJIN PF15077.6 CDJ45908.1 - 9.9 5.9 13.5 12 5.6 13.5 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Presenilin PF01080.17 CDJ45909.1 - 0.063 12.0 7.8 0.077 11.8 7.8 1.2 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 CDJ45909.1 - 0.082 12.8 2.6 0.11 12.4 2.6 1.3 1 0 0 1 1 1 0 N-glycosylation protein DUF4834 PF16118.5 CDJ45909.1 - 1.7 9.7 16.1 0.56 11.2 10.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4407 PF14362.6 CDJ45909.1 - 2.2 7.6 8.7 2.5 7.4 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3464 PF11947.8 CDJ45909.1 - 4.7 7.0 8.9 8.8 6.1 8.9 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 MscS_TM PF12794.7 CDJ45909.1 - 9.5 5.0 11.1 16 4.2 11.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2722 PF10846.8 CDJ45910.1 - 0.0024 16.9 15.2 0.023 13.7 4.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ45910.1 - 0.0066 16.5 2.9 0.0066 16.5 2.9 3.6 2 1 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 CDJ45910.1 - 0.095 13.5 23.2 1 10.2 7.8 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 TERB2 PF15101.6 CDJ45910.1 - 0.49 10.4 10.2 0.44 10.6 2.2 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Roughex PF06020.11 CDJ45910.1 - 1.1 8.2 14.6 1.4 7.9 1.1 2.1 2 0 0 2 2 2 0 Drosophila roughex protein AAA_23 PF13476.6 CDJ45910.1 - 1.5 9.3 8.3 5.3 7.5 3.5 2.2 2 0 0 2 2 2 0 AAA domain DUF4834 PF16118.5 CDJ45910.1 - 1.7 9.7 9.3 8.9 7.3 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ45910.1 - 3.6 7.5 10.2 4.1 7.3 2.3 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) MITF_TFEB_C_3_N PF15951.5 CDJ45910.1 - 4.7 7.8 28.0 5.5 7.6 11.8 2.4 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus DUF702 PF05142.12 CDJ45910.1 - 6.1 7.3 7.5 7.3 7.1 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) TMA7 PF09072.10 CDJ45910.1 - 7.9 7.4 13.1 3.7 8.5 4.5 2.5 2 0 0 2 2 2 0 Translation machinery associated TMA7 DUF2828 PF11443.8 CDJ45911.1 - 2 6.4 9.0 1.9 6.5 9.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Suf PF05843.14 CDJ45911.1 - 3 7.8 17.9 3.6 7.5 17.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ45911.1 - 3.1 7.7 31.3 3.5 7.5 31.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.3 CDJ45911.1 - 3.6 7.8 10.7 4.1 7.6 10.7 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Pex14_N PF04695.13 CDJ45911.1 - 6 7.5 21.1 7.8 7.1 21.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DivIC PF04977.15 CDJ45911.1 - 9.8 6.0 19.7 16 5.3 19.7 1.3 1 0 0 1 1 1 0 Septum formation initiator OATP PF03137.20 CDJ45911.1 - 9.9 4.3 6.2 10 4.3 6.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.25 CDJ45912.1 - 5.2e-13 48.9 0.0 2e-12 47.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase polyprenyl_synt PF00348.17 CDJ45916.1 - 1.1e-59 201.6 0.1 7.3e-55 185.8 0.0 2.8 2 1 0 2 2 2 2 Polyprenyl synthetase LAMTOR PF15454.6 CDJ45916.1 - 0.21 12.2 1.5 0.42 11.3 1.5 1.4 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator SHS2_Rpb7-N PF03876.17 CDJ45917.1 - 6.3e-13 48.9 0.1 1e-12 48.2 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CDJ45917.1 - 1.8e-07 31.4 0.0 3.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 CDJ45917.1 - 0.059 13.6 0.0 0.083 13.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DRY_EERY PF09750.9 CDJ45918.1 - 2.2e-08 34.4 0.9 2.2e-08 34.4 0.9 4.3 4 0 0 4 4 4 1 Alternative splicing regulator Surp PF01805.20 CDJ45918.1 - 1.9e-06 27.8 0.5 4.2e-05 23.4 0.1 2.5 2 0 0 2 2 2 1 Surp module LRR_4 PF12799.7 CDJ45919.1 - 2.2e-18 66.0 24.0 6.5e-06 26.4 3.5 5.5 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ45919.1 - 4.5e-13 48.8 25.1 1.6e-08 34.2 6.1 4.4 3 1 1 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 CDJ45919.1 - 1.7e-12 47.2 0.1 5.1e-06 26.1 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CDJ45919.1 - 1.5e-06 27.8 16.6 0.099 12.7 0.1 6.3 5 1 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 CDJ45919.1 - 0.0063 16.9 22.1 1.6 9.5 0.0 7.8 6 1 0 6 6 6 2 Leucine Rich Repeat DUF4381 PF14316.6 CDJ45920.1 - 0.054 13.7 2.7 0.09 13.0 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ribosomal_S19 PF00203.21 CDJ45921.1 - 2.6e-30 104.1 0.1 3.7e-30 103.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 RT_RNaseH_2 PF17919.1 CDJ45922.1 - 7.4e-11 42.0 0.0 1.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CS PF04969.16 CDJ45922.1 - 9.3e-05 23.4 0.0 0.00015 22.7 0.0 1.3 1 0 0 1 1 1 1 CS domain SGS PF05002.15 CDJ45922.1 - 0.00013 22.0 0.4 0.00043 20.4 0.3 1.9 2 0 0 2 2 2 1 SGS domain RT_RNaseH PF17917.1 CDJ45922.1 - 0.00029 21.1 0.0 0.0007 19.9 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ45923.1 - 6.4e-11 42.2 0.0 1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CDJ45924.1 - 0.098 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 CDJ45926.1 - 1.6e-10 40.5 10.9 5.1e-05 23.2 1.1 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ45926.1 - 0.00076 19.1 8.4 0.0094 15.6 1.1 2.5 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger DnaJ_CXXCXGXG PF00684.19 CDJ45926.1 - 0.0027 18.0 5.1 0.0054 17.1 5.1 1.4 1 0 0 1 1 1 1 DnaJ central domain zf-CCHC_2 PF13696.6 CDJ45926.1 - 0.0028 17.4 6.9 0.0032 17.2 0.8 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ45926.1 - 0.0063 16.4 6.3 0.14 12.1 1.4 2.4 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 CDJ45926.1 - 0.058 13.1 7.7 2.5 7.9 0.6 3.5 3 0 0 3 3 3 0 Zinc knuckle eIF3g PF12353.8 CDJ45926.1 - 1.5 9.2 6.9 12 6.3 0.3 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G RVP_2 PF08284.11 CDJ45927.1 - 2e-09 37.3 0.0 3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ45927.1 - 2e-08 34.7 0.0 3.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ45927.1 - 5.1e-08 33.4 0.0 2.1e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ45927.1 - 0.0014 18.9 0.0 0.0032 17.7 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ45927.1 - 0.0036 17.1 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease SUIM_assoc PF16619.5 CDJ45928.1 - 0.082 13.0 8.4 0.37 10.9 0.2 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 eIF-3_zeta PF05091.12 CDJ45929.1 - 8 5.3 10.7 13 4.7 10.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ZZ PF00569.17 CDJ45930.1 - 2.3e-09 36.9 7.4 5.6e-09 35.7 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CDJ45930.1 - 3.8e-08 33.4 0.0 6.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 CDJ45930.1 - 0.0005 20.3 8.0 0.0011 19.2 8.0 1.6 1 0 0 1 1 1 1 C1 domain RskA PF10099.9 CDJ45930.1 - 0.0095 16.2 5.4 0.0095 16.2 5.4 4.1 2 1 1 3 3 3 1 Anti-sigma-K factor rskA Herpes_pp85 PF04637.12 CDJ45930.1 - 3 6.2 9.3 0.42 9.0 5.0 1.6 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF2052 PF09747.9 CDJ45932.1 - 0.0055 16.9 8.1 0.0059 16.7 8.1 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF572 PF04502.13 CDJ45932.1 - 0.055 13.1 8.5 0.065 12.9 8.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nha1_C PF08619.10 CDJ45932.1 - 0.059 12.6 9.2 0.068 12.4 9.2 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Neur_chan_memb PF02932.16 CDJ45932.1 - 0.062 13.4 9.5 0.069 13.2 9.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ45932.1 - 0.074 11.8 11.8 0.084 11.6 11.8 1.3 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ45932.1 - 0.38 8.6 11.6 0.45 8.4 11.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MecA PF05389.12 CDJ45932.1 - 1 9.0 10.9 1.6 8.3 10.9 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Sporozoite_P67 PF05642.11 CDJ45932.1 - 7.6 4.5 7.1 10 4.1 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LAP1C PF05609.12 CDJ45933.1 - 0.044 12.9 33.0 0.059 12.4 33.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SDA1 PF05285.12 CDJ45933.1 - 0.076 12.4 19.1 0.14 11.5 19.1 1.3 1 0 0 1 1 1 0 SDA1 SMYLE_N PF18615.1 CDJ45933.1 - 0.15 11.6 29.9 0.24 10.9 29.9 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Hid1 PF12722.7 CDJ45933.1 - 0.2 9.7 27.9 0.27 9.3 27.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF5523 PF17661.1 CDJ45933.1 - 0.38 10.4 18.3 0.62 9.7 18.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) MMR1 PF08505.10 CDJ45933.1 - 0.71 10.1 41.8 1.2 9.4 41.8 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PPP4R2 PF09184.11 CDJ45933.1 - 3.2 7.3 23.8 4.6 6.7 23.8 1.2 1 0 0 1 1 1 0 PPP4R2 Peptidase_S64 PF08192.11 CDJ45933.1 - 6.3 5.2 34.0 8.2 4.8 34.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Raftlin PF15250.6 CDJ45933.1 - 8.2 5.1 27.9 12 4.5 27.9 1.2 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 CDJ45933.1 - 8.2 5.3 29.2 14 4.6 29.2 1.4 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 CDJ45933.1 - 9.1 4.4 25.7 14 3.8 25.7 1.3 1 0 0 1 1 1 0 CDC45-like protein RskA PF10099.9 CDJ45934.1 - 0.0072 16.6 22.3 0.0072 16.6 22.3 2.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA GramPos_pilinD3 PF16570.5 CDJ45934.1 - 0.042 14.6 0.1 0.067 13.9 0.1 1.3 1 0 0 1 1 1 0 Gram-positive pilin backbone subunit 3, Cna-B-like domain BAF1_ABF1 PF04684.13 CDJ45934.1 - 0.34 9.9 28.6 0.45 9.5 28.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pescadillo_N PF06732.11 CDJ45935.1 - 3.9e-09 36.5 0.1 3.9e-09 36.5 0.1 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus TFIIA PF03153.13 CDJ45935.1 - 2 8.3 39.3 2.9 7.8 39.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0020 PF01170.18 CDJ45937.1 - 0.0033 17.1 1.2 0.012 15.3 0.0 2.3 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 TFIIA PF03153.13 CDJ45937.1 - 0.033 14.2 60.4 0.97 9.4 10.4 4.1 4 0 0 4 4 4 0 Transcription factor IIA, alpha/beta subunit DUF4667 PF15700.5 CDJ45937.1 - 1.3 9.0 13.9 24 4.9 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4667) DUF5320 PF17253.2 CDJ45937.1 - 6.5 7.9 16.4 6.5 7.9 0.9 3.9 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Cwf_Cwc_15 PF04889.12 CDJ45938.1 - 7e-07 29.2 15.7 9.6e-07 28.8 15.7 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 CDJ45938.1 - 0.00076 19.2 52.7 0.0011 18.7 15.0 2.1 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ45938.1 - 0.012 15.2 28.4 0.012 15.2 28.4 2.1 2 0 0 2 2 2 0 Spt20 family SPX PF03105.19 CDJ45938.1 - 0.025 14.5 25.9 0.035 14.0 25.9 1.2 1 0 0 1 1 1 0 SPX domain CCDC106 PF15794.5 CDJ45938.1 - 0.045 13.5 32.9 0.089 12.5 7.8 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 FAM176 PF14851.6 CDJ45938.1 - 0.1 12.3 9.9 0.069 12.8 2.2 2.1 2 0 0 2 2 2 0 FAM176 family Activator_LAG-3 PF11498.8 CDJ45938.1 - 0.28 10.1 56.8 0.56 9.1 24.1 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Zip PF02535.22 CDJ45938.1 - 0.32 10.2 9.9 0.2 10.9 1.6 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter AIF_C PF14721.6 CDJ45938.1 - 0.37 11.1 12.5 0.18 12.2 1.6 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1840 PF08895.11 CDJ45938.1 - 2.2 8.7 11.4 3.3 8.1 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) MPM1 PF17234.2 CDJ45938.1 - 3.1 8.0 27.8 0.4 10.9 12.4 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 V_ATPase_I PF01496.19 CDJ45938.1 - 3.4 5.5 20.6 0.12 10.3 7.9 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Afi1 PF07792.12 CDJ45938.1 - 4.7 7.7 20.8 2 8.9 10.2 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FHIPEP PF00771.20 CDJ45938.1 - 6.3 5.1 12.6 0.39 9.1 1.8 2.1 2 0 0 2 2 2 0 FHIPEP family DUF3408 PF11888.8 CDJ45938.1 - 6.9 6.8 20.4 8.9 6.4 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF1631 PF07793.11 CDJ45938.1 - 8.6 4.6 32.7 12 4.1 32.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) ARF7EP_C PF14949.6 CDJ45938.1 - 9.7 6.9 18.6 6.8 7.4 4.0 2.2 2 0 0 2 2 2 0 ARF7 effector protein C-terminus POP1 PF06978.11 CDJ45940.1 - 7.3e-25 88.2 9.1 7.3e-25 88.2 9.1 7.9 6 1 0 7 7 7 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CDJ45940.1 - 2.1e-17 63.2 0.0 2.1e-17 63.2 0.0 6.5 5 2 2 7 7 7 1 POPLD (NUC188) domain Activator_LAG-3 PF11498.8 CDJ45941.1 - 0.055 12.4 22.8 0.1 11.5 22.8 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 zinc_ribbon_2 PF13240.6 CDJ45941.1 - 0.06 13.1 0.9 0.15 11.8 0.9 1.7 1 0 0 1 1 1 0 zinc-ribbon domain TFIIA PF03153.13 CDJ45941.1 - 0.77 9.7 17.9 0.1 12.5 13.7 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit eIF-5_eIF-2B PF01873.17 CDJ45941.1 - 1.7 8.5 5.1 33 4.4 0.0 2.9 2 1 0 3 3 3 0 Domain found in IF2B/IF5 DUF4770 PF15994.5 CDJ45941.1 - 2.3 8.4 7.8 3.9 7.7 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Pkinase PF00069.25 CDJ45942.1 - 1.5e-41 142.6 7.9 4.7e-22 78.6 0.1 4.3 2 1 2 5 5 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ45942.1 - 2.4e-17 63.1 6.8 7.9e-16 58.1 1.0 3.5 1 1 0 2 2 2 1 Protein tyrosine kinase SPX PF03105.19 CDJ45942.1 - 0.00034 20.7 24.3 0.014 15.3 6.0 2.3 2 0 0 2 2 2 2 SPX domain SR-25 PF10500.9 CDJ45942.1 - 0.00074 19.2 7.1 0.00074 19.2 7.1 4.2 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein SLC12 PF03522.15 CDJ45942.1 - 0.31 10.0 28.5 1.1 8.2 13.2 2.1 2 0 0 2 2 2 0 Solute carrier family 12 SpoIIP PF07454.11 CDJ45942.1 - 0.34 10.3 27.7 2.1 7.7 1.8 3.2 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) TCP PF03634.13 CDJ45942.1 - 0.36 11.4 39.3 0.8 10.3 8.0 4.0 4 0 0 4 4 4 0 TCP family transcription factor DUF4569 PF15133.6 CDJ45942.1 - 0.41 10.3 34.1 0.19 11.4 4.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4569) RR_TM4-6 PF06459.12 CDJ45942.1 - 2.1 8.1 30.8 0.81 9.5 7.3 3.2 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 Exonuc_VII_L PF02601.15 CDJ45942.1 - 2.6 7.6 34.9 2.7 7.5 12.5 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit EOS1 PF12326.8 CDJ45942.1 - 7.2 6.5 19.4 12 5.8 2.1 3.4 3 0 0 3 3 3 0 N-glycosylation protein DUF4834 PF16118.5 CDJ45942.1 - 7.3 7.6 42.5 0.44 11.5 6.4 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) DUF702 PF05142.12 CDJ45942.1 - 7.5 7.0 30.6 12 6.3 2.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF702) GBP_C PF02841.14 CDJ45943.1 - 0.028 13.8 26.6 0.041 13.3 26.6 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain ThiF PF00899.21 CDJ45943.1 - 0.092 12.1 4.4 0.67 9.3 4.4 2.0 1 1 0 1 1 1 0 ThiF family Methyltransf_32 PF13679.6 CDJ45944.1 - 0.00097 19.2 12.0 0.00097 19.2 12.0 4.4 2 1 1 3 3 3 1 Methyltransferase domain Ribosomal_60s PF00428.19 CDJ45944.1 - 0.0018 18.8 7.6 0.0018 18.8 7.6 4.6 4 1 0 4 4 4 1 60s Acidic ribosomal protein CDC45 PF02724.14 CDJ45944.1 - 0.0044 15.4 11.5 0.0044 15.4 11.5 3.3 2 1 1 3 3 3 1 CDC45-like protein SMC_hinge PF06470.13 CDJ45945.1 - 2e-06 28.1 0.3 2e-06 28.1 0.3 3.0 3 1 0 3 3 3 1 SMC proteins Flexible Hinge Domain DUF1682 PF07946.14 CDJ45946.1 - 4.7 6.3 10.1 5.1 6.2 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) UQ_con PF00179.26 CDJ45949.1 - 3.8e-17 62.2 5.3 1.1e-16 60.7 4.8 2.1 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme RR_TM4-6 PF06459.12 CDJ45949.1 - 0.064 13.1 37.9 0.71 9.6 14.2 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 CDJ45949.1 - 2.6 7.9 99.4 3.5 7.5 55.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 CDJ45950.1 - 0.62 9.2 38.8 0.8 8.8 38.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 CDJ45950.1 - 4 7.3 17.9 4.7 7.1 17.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ45950.1 - 6.9 6.8 13.2 9.9 6.3 13.2 1.4 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CDC27 PF09507.10 CDJ45950.1 - 7.3 5.9 18.4 8.4 5.7 18.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RskA PF10099.9 CDJ45951.1 - 0.055 13.8 0.3 0.055 13.8 0.3 8.1 2 1 5 7 7 7 0 Anti-sigma-K factor rskA Tetraspanin PF00335.20 CDJ45951.1 - 5.1 6.7 9.4 9.3 5.9 0.1 3.7 1 1 1 2 2 2 0 Tetraspanin family AP2 PF00847.20 CDJ45952.1 - 1.6e-06 28.3 0.3 1.6e-06 28.3 0.3 2.6 4 0 0 4 4 1 1 AP2 domain DUF1525 PF07511.11 CDJ45952.1 - 0.025 14.7 12.7 0.025 14.7 12.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) PIG-S PF10510.9 CDJ45952.1 - 0.056 12.3 4.5 0.089 11.6 4.5 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Exonuc_VII_L PF02601.15 CDJ45952.1 - 0.057 13.0 8.8 0.099 12.2 8.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3533 PF12051.8 CDJ45952.1 - 0.12 11.2 6.9 0.18 10.7 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) SKA1 PF07160.12 CDJ45952.1 - 0.13 12.1 9.4 0.23 11.3 9.4 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 WGG PF10273.9 CDJ45952.1 - 0.13 12.9 1.4 0.27 11.9 1.4 1.5 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 EIF4E-T PF10477.9 CDJ45952.1 - 0.22 10.3 13.0 0.34 9.7 13.0 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PepSY_TM_like_2 PF16357.5 CDJ45952.1 - 0.45 10.5 6.1 0.77 9.7 6.1 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like RHD3 PF05879.12 CDJ45952.1 - 0.61 8.2 4.9 0.82 7.7 4.9 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) UPF0560 PF10577.9 CDJ45952.1 - 1 7.8 15.3 1.6 7.1 15.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Spore_III_AF PF09581.10 CDJ45952.1 - 2 8.4 8.5 3.4 7.7 8.5 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF3584 PF12128.8 CDJ45952.1 - 2.9 5.3 18.2 3.9 4.8 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RRP36 PF06102.12 CDJ45952.1 - 4 7.4 12.0 7.5 6.5 12.0 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 LMBR1 PF04791.16 CDJ45952.1 - 7.2 5.4 4.8 10 4.9 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein AF-4 PF05110.13 CDJ45952.1 - 7.3 4.5 21.3 1.2 7.2 3.8 2.4 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Prominin PF05478.11 CDJ45952.1 - 8.6 4.2 11.1 12 3.8 11.1 1.0 1 0 0 1 1 1 0 Prominin Isochorismatase PF00857.20 CDJ45955.1 - 1e-21 77.9 0.5 3.6e-18 66.4 0.4 2.3 2 1 0 2 2 2 2 Isochorismatase family Cys_Met_Meta_PP PF01053.20 CDJ45957.1 - 1.6e-112 375.9 0.0 5.2e-64 216.2 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CDJ45957.1 - 8.8e-07 28.5 0.0 2.5e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CDJ45957.1 - 0.026 13.7 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II SR-25 PF10500.9 CDJ45958.1 - 0.00083 19.0 9.3 0.00083 19.0 9.3 10.1 8 2 2 10 10 10 4 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ45959.1 - 0.061 12.9 25.4 0.072 12.7 25.4 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LTV PF04180.14 CDJ45959.1 - 6.9 6.3 19.7 8.1 6.1 19.7 1.0 1 0 0 1 1 1 0 Low temperature viability protein NUDE_C PF04880.13 CDJ45959.1 - 9.5 6.7 20.5 10 6.6 20.5 1.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF4834 PF16118.5 CDJ45960.1 - 0.0016 19.3 0.8 0.0016 19.3 0.8 5.2 3 2 0 3 3 3 1 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ45960.1 - 0.0083 16.2 17.5 0.0083 16.2 17.5 3.7 2 1 1 3 3 3 2 Transcription factor IIA, alpha/beta subunit DcuA_DcuB PF03605.14 CDJ45960.1 - 0.02 13.8 0.1 0.02 13.8 0.1 3.2 3 0 0 3 3 3 0 Anaerobic c4-dicarboxylate membrane transporter INSIG PF07281.12 CDJ45960.1 - 0.02 14.6 0.0 0.02 14.6 0.0 3.5 3 1 0 3 3 3 0 Insulin-induced protein (INSIG) Serinc PF03348.15 CDJ45960.1 - 0.053 12.4 0.1 0.053 12.4 0.1 3.1 3 0 0 3 3 3 0 Serine incorporator (Serinc) DUF4199 PF13858.6 CDJ45960.1 - 0.23 11.8 0.1 0.23 11.8 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4199) Connexin PF00029.19 CDJ45960.1 - 0.43 10.3 28.3 0.56 9.9 0.6 3.5 3 0 0 3 3 3 0 Connexin AF-4 PF05110.13 CDJ45960.1 - 5.3 5.0 56.5 0.91 7.5 42.1 2.4 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DUF1635 PF07795.11 CDJ45961.1 - 0.012 15.5 3.3 0.012 15.5 3.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) Erg28 PF03694.13 CDJ45961.1 - 0.017 15.5 0.8 0.057 13.8 0.8 1.9 1 0 0 1 1 1 0 Erg28 like protein Acetyltransf_11 PF13720.6 CDJ45961.1 - 0.22 12.0 1.5 0.3 11.6 0.0 2.0 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Pap_E4 PF02711.14 CDJ45961.1 - 5.4 8.0 6.2 1.1 10.2 1.7 2.1 2 0 0 2 2 2 0 E4 protein DAO PF01266.24 CDJ45962.1 - 7e-11 42.3 1.5 1.2e-10 41.6 1.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase SAPS PF04499.15 CDJ45962.1 - 0.023 13.5 8.4 0.023 13.5 8.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CLN3 PF02487.17 CDJ45962.1 - 0.24 10.4 3.0 0.37 9.8 3.0 1.2 1 0 0 1 1 1 0 CLN3 protein Prismane PF03063.20 CDJ45962.1 - 0.64 8.6 9.5 0.88 8.2 9.5 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family SID-1_RNA_chan PF13965.6 CDJ45962.1 - 1.5 7.2 3.4 2 6.7 3.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 CDJ45962.1 - 2.1 7.5 10.7 3.6 6.7 10.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter NESP55 PF06390.12 CDJ45962.1 - 3 7.4 40.8 0.83 9.2 14.2 2.3 1 1 1 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) CDC45 PF02724.14 CDJ45962.1 - 3.7 5.7 22.1 4.5 5.5 22.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CDJ45962.1 - 7.6 4.6 29.6 9.9 4.2 29.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4148 PF13663.6 CDJ45962.1 - 7.7 6.8 10.9 21 5.4 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) SR-25 PF10500.9 CDJ45963.1 - 6.9e-05 22.6 25.1 8.2e-05 22.3 25.1 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3682 PF12446.8 CDJ45963.1 - 0.11 13.0 28.6 0.13 12.8 28.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) TFIIA PF03153.13 CDJ45963.1 - 0.43 10.5 30.5 0.44 10.5 30.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ45963.1 - 0.66 10.2 12.7 1.5 9.1 12.7 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Velvet PF11754.8 CDJ45963.1 - 1.7 8.5 17.6 2 8.3 17.6 1.1 1 0 0 1 1 1 0 Velvet factor CDC45 PF02724.14 CDJ45963.1 - 1.8 6.8 18.4 2.1 6.6 18.4 1.0 1 0 0 1 1 1 0 CDC45-like protein IHABP4_N PF16174.5 CDJ45963.1 - 2.2 8.9 22.9 3.1 8.4 22.9 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal SprA-related PF12118.8 CDJ45963.1 - 2.5 7.2 28.4 2.9 7.0 28.4 1.1 1 0 0 1 1 1 0 SprA-related family Zip PF02535.22 CDJ45963.1 - 3 7.0 12.7 3.5 6.8 12.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 CDJ45963.1 - 3.1 7.8 13.6 4.8 7.1 13.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A eIF-3_zeta PF05091.12 CDJ45963.1 - 4.8 6.0 17.9 5.5 5.8 17.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Striatin PF08232.12 CDJ45963.1 - 5 7.7 19.8 7.4 7.1 19.8 1.2 1 0 0 1 1 1 0 Striatin family Hydin_ADK PF17213.3 CDJ45963.1 - 6.9 6.9 19.4 8.9 6.5 19.4 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 CDJ45963.1 - 7.7 5.2 24.8 8.4 5.0 24.8 1.0 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 CDJ45963.1 - 8.8 5.8 18.8 9.8 5.7 18.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) PA26 PF04636.13 CDJ45963.1 - 9.6 5.0 12.3 11 4.9 12.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RskA PF10099.9 CDJ45964.1 - 0.0025 18.2 9.4 0.012 15.9 9.4 2.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Pom PF17251.2 CDJ45966.1 - 0.018 14.4 1.6 0.021 14.2 1.6 1.0 1 0 0 1 1 1 0 Protochlamydia outer membrane protein DUF702 PF05142.12 CDJ45966.1 - 0.025 15.1 4.8 0.026 15.0 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Spt20 PF12090.8 CDJ45966.1 - 0.033 13.8 13.6 0.035 13.7 13.6 1.0 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ45966.1 - 0.043 12.6 11.9 0.043 12.7 11.9 1.0 1 0 0 1 1 1 0 Androgen receptor PDGF_N PF04692.13 CDJ45966.1 - 0.068 14.0 6.0 0.088 13.6 6.0 1.1 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region DUF2722 PF10846.8 CDJ45966.1 - 0.071 12.0 11.7 0.07 12.1 11.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ45966.1 - 0.29 12.1 5.8 0.3 12.1 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) NINJA_B PF16136.5 CDJ45966.1 - 0.3 11.5 7.8 0.34 11.3 7.8 1.1 1 0 0 1 1 1 0 Putative nuclear localisation signal Roughex PF06020.11 CDJ45966.1 - 0.38 9.8 6.9 0.37 9.9 6.9 1.0 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ45966.1 - 0.69 9.8 13.2 0.7 9.8 13.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ45966.1 - 1.6 7.4 5.8 1.7 7.4 5.8 1.0 1 0 0 1 1 1 0 Presenilin DUF5423 PF17461.2 CDJ45966.1 - 2.6 6.8 7.2 2.9 6.7 7.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) RBP_receptor PF14752.6 CDJ45966.1 - 5.9 5.3 6.0 6.6 5.2 6.0 1.0 1 0 0 1 1 1 0 Retinol binding protein receptor Mak16 PF04874.14 CDJ45967.1 - 0.012 16.3 2.0 0.012 16.3 2.0 1.7 2 0 0 2 2 2 0 Mak16 protein C-terminal region FHIPEP PF00771.20 CDJ45967.1 - 0.094 11.2 3.3 0.11 11.0 3.3 1.1 1 0 0 1 1 1 0 FHIPEP family TFIIA PF03153.13 CDJ45967.1 - 0.39 10.6 37.7 0.49 10.3 37.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF913 PF06025.12 CDJ45967.1 - 2.9 6.8 7.0 3 6.7 7.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2828 PF11443.8 CDJ45967.1 - 3 5.8 10.9 3.3 5.7 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SLC12 PF03522.15 CDJ45967.1 - 3.3 6.6 9.6 3.5 6.5 9.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Band_3_cyto PF07565.13 CDJ45967.1 - 5 6.9 9.4 6.2 6.5 9.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.12 CDJ45967.1 - 7.3 5.4 15.4 8.4 5.2 15.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ45968.1 - 5.7e-05 23.3 24.8 0.0022 18.1 9.9 2.3 2 0 0 2 2 2 2 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ45968.1 - 0.00019 21.1 70.7 0.026 14.1 40.3 2.2 2 0 0 2 2 2 2 Spt20 family Presenilin PF01080.17 CDJ45968.1 - 0.0002 20.3 23.6 0.0014 17.5 11.1 2.0 2 0 0 2 2 2 2 Presenilin SLC12 PF03522.15 CDJ45968.1 - 0.00039 19.6 17.3 0.026 13.6 8.3 2.0 2 0 0 2 2 2 2 Solute carrier family 12 Velvet PF11754.8 CDJ45968.1 - 0.0008 19.4 16.7 0.0064 16.5 5.8 2.1 2 0 0 2 2 2 2 Velvet factor EPL1 PF10513.9 CDJ45968.1 - 0.00085 19.7 22.4 0.035 14.5 9.4 2.4 2 0 0 2 2 2 2 Enhancer of polycomb-like TFIIA PF03153.13 CDJ45968.1 - 0.0022 18.0 61.4 0.096 12.7 17.8 2.0 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF5308 PF17233.2 CDJ45968.1 - 0.0024 18.1 1.7 0.0024 18.1 1.7 2.2 1 1 1 2 2 2 1 Family of unknown function (DUF5308) SARAF PF06682.12 CDJ45968.1 - 0.0052 16.5 5.7 0.0052 16.5 5.7 2.2 1 1 1 2 2 1 1 SOCE-associated regulatory factor of calcium homoeostasis Connexin PF00029.19 CDJ45968.1 - 0.0058 16.4 16.4 0.029 14.1 6.6 2.3 2 0 0 2 2 2 1 Connexin SID-1_RNA_chan PF13965.6 CDJ45968.1 - 0.0068 14.9 4.9 0.031 12.7 0.7 2.0 2 0 0 2 2 2 1 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ45968.1 - 0.012 15.7 17.4 0.46 10.5 9.9 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RP-C_C PF11800.8 CDJ45968.1 - 0.019 15.1 18.1 0.18 11.9 9.2 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region EIIBC-GUT_N PF03612.14 CDJ45968.1 - 0.02 14.6 0.3 0.02 14.6 0.3 2.5 2 1 0 2 2 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4820 PF16091.5 CDJ45968.1 - 0.029 13.7 20.9 0.3 10.4 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Apc15p PF05841.11 CDJ45968.1 - 0.033 15.0 5.1 0.033 15.0 5.1 2.3 2 0 0 2 2 2 0 Apc15p protein SpoIIP PF07454.11 CDJ45968.1 - 0.045 13.2 28.2 0.38 10.2 15.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RNA_pol_Rpc4 PF05132.14 CDJ45968.1 - 0.051 14.0 22.6 0.057 13.8 9.4 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF702 PF05142.12 CDJ45968.1 - 0.071 13.6 21.6 0.2 12.1 8.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF4746 PF15928.5 CDJ45968.1 - 0.079 12.4 23.9 0.44 9.9 12.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CNDH2_C PF16858.5 CDJ45968.1 - 0.097 12.5 26.4 0.18 11.7 12.8 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Eapp_C PF10238.9 CDJ45968.1 - 0.1 12.7 26.0 0.42 10.7 3.8 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein CPSF100_C PF13299.6 CDJ45968.1 - 0.1 12.8 23.4 0.1 12.8 2.2 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TCP PF03634.13 CDJ45968.1 - 0.14 12.7 22.8 0.48 11.0 0.8 2.2 2 0 0 2 2 2 0 TCP family transcription factor DUF3295 PF11702.8 CDJ45968.1 - 0.2 11.0 23.1 0.43 9.9 12.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) DUF913 PF06025.12 CDJ45968.1 - 0.21 10.5 15.7 0.24 10.4 7.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SOBP PF15279.6 CDJ45968.1 - 0.21 12.1 18.6 0.56 10.8 8.0 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein DUF4050 PF13259.6 CDJ45968.1 - 0.22 11.8 20.8 0.33 11.3 9.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Endostatin PF06482.11 CDJ45968.1 - 0.25 10.8 20.6 0.81 9.1 0.8 2.0 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Endonuclease_NS PF01223.23 CDJ45968.1 - 0.28 11.0 15.1 0.13 12.1 0.5 3.6 3 1 1 4 4 2 0 DNA/RNA non-specific endonuclease Dynamin_N PF00350.23 CDJ45968.1 - 0.29 11.2 7.7 2.8 7.9 2.3 2.2 2 0 0 2 2 2 0 Dynamin family FAM76 PF16046.5 CDJ45968.1 - 0.31 10.4 25.3 0.96 8.7 13.8 2.1 2 0 0 2 2 2 0 FAM76 protein SRP-alpha_N PF04086.13 CDJ45968.1 - 0.32 10.9 26.1 1.3 8.9 15.0 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF4484 PF14831.6 CDJ45968.1 - 0.37 10.8 18.7 0.32 11.0 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Spem1 PF15670.5 CDJ45968.1 - 0.38 10.3 20.4 0.56 9.7 7.8 2.2 2 0 0 2 2 2 0 Spermatid maturation protein 1 Prothymosin PF03247.14 CDJ45968.1 - 0.41 11.1 28.4 0.18 12.3 16.1 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family CNDH2_M PF16869.5 CDJ45968.1 - 0.42 11.3 21.7 2.6 8.7 11.4 2.2 2 0 0 2 2 2 0 PF16858 DUF4770 PF15994.5 CDJ45968.1 - 0.42 10.8 27.6 0.072 13.3 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Band_3_cyto PF07565.13 CDJ45968.1 - 0.43 10.3 22.8 0.91 9.3 11.3 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain MID_MedPIWI PF18296.1 CDJ45968.1 - 0.44 10.3 20.6 2.3 7.9 1.2 2.1 2 0 0 2 2 2 0 MID domain of medPIWI DUF3807 PF12720.7 CDJ45968.1 - 0.44 10.8 38.2 1.1 9.5 7.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Peptidase_S64 PF08192.11 CDJ45968.1 - 0.47 8.9 17.2 0.5 8.8 8.4 2.0 2 0 0 2 2 2 0 Peptidase family S64 Pex14_N PF04695.13 CDJ45968.1 - 0.49 11.0 43.0 0.78 10.4 11.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.6 CDJ45968.1 - 0.5 10.0 20.0 0.31 10.7 0.8 2.4 2 0 0 2 2 2 0 FAM176 family DUF572 PF04502.13 CDJ45968.1 - 0.57 9.7 22.5 1.6 8.3 12.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4045 PF13254.6 CDJ45968.1 - 0.58 9.7 21.8 0.36 10.4 10.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) CCSAP PF15748.5 CDJ45968.1 - 0.6 10.2 32.3 1.7 8.7 18.7 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Ctr PF04145.15 CDJ45968.1 - 0.62 10.7 14.1 3.4 8.3 6.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family DUF4228 PF14009.6 CDJ45968.1 - 0.63 10.4 12.9 4 7.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Nha1_C PF08619.10 CDJ45968.1 - 0.65 9.1 32.3 1.6 7.8 5.7 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Vfa1 PF08432.10 CDJ45968.1 - 0.68 10.2 27.5 2.9 8.2 16.0 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.6 CDJ45968.1 - 0.79 9.7 20.0 2.7 7.9 2.0 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DUF4407 PF14362.6 CDJ45968.1 - 0.85 8.9 40.5 1.6 8.0 40.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Pox_Ag35 PF03286.14 CDJ45968.1 - 0.94 9.2 21.0 0.6 9.9 0.8 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Zip PF02535.22 CDJ45968.1 - 0.94 8.6 14.2 0.96 8.6 6.6 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter DUF3499 PF12005.8 CDJ45968.1 - 0.97 10.1 13.1 1.9 9.1 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) GvpL_GvpF PF06386.11 CDJ45968.1 - 1 9.2 21.6 1.8 8.4 6.3 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF BAT2_N PF07001.11 CDJ45968.1 - 1.1 9.7 32.5 2.6 8.4 6.1 2.3 2 0 0 2 2 2 0 BAT2 N-terminus RIC3 PF15361.6 CDJ45968.1 - 1.1 9.7 16.2 2.4 8.5 0.5 2.3 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Serinc PF03348.15 CDJ45968.1 - 1.1 8.1 15.0 0.19 10.6 4.6 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) UPF0560 PF10577.9 CDJ45968.1 - 1.1 7.7 41.4 0.79 8.2 19.8 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 GramPos_pilinD1 PF16555.5 CDJ45968.1 - 1.1 9.4 17.3 1.6 8.9 2.4 2.4 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain MAJIN PF15077.6 CDJ45968.1 - 1.2 8.9 21.3 0.67 9.7 8.4 2.4 2 0 0 2 2 2 0 Membrane-anchored junction protein TraV PF09676.10 CDJ45968.1 - 1.3 10.0 24.5 3 8.8 11.5 2.2 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) DUF2464 PF10240.9 CDJ45968.1 - 1.4 8.4 14.6 1.6 8.2 0.2 2.1 2 0 0 2 2 2 0 Multivesicular body subunit 12 Spore_coat_CotO PF14153.6 CDJ45968.1 - 1.5 8.7 42.2 4 7.3 11.3 2.1 2 0 0 2 2 2 0 Spore coat protein CotO MAP17 PF15807.5 CDJ45968.1 - 1.5 9.1 22.8 0.59 10.4 11.8 2.2 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 eIF-3_zeta PF05091.12 CDJ45968.1 - 1.5 7.7 41.3 0.76 8.7 8.5 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DAG_kinase_N PF14513.6 CDJ45968.1 - 1.6 8.9 21.9 4.5 7.5 11.9 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Peptidase_S49_N PF08496.10 CDJ45968.1 - 1.8 8.6 23.3 0.55 10.3 3.3 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PIP5K PF01504.18 CDJ45968.1 - 1.8 7.7 26.2 0.036 13.3 1.1 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase PAT1 PF09770.9 CDJ45968.1 - 1.9 6.7 44.0 1.4 7.0 24.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CTU2 PF10288.9 CDJ45968.1 - 2.7 8.3 27.0 6.2 7.1 14.7 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 XRN_M PF17846.1 CDJ45968.1 - 3.3 6.6 20.5 0.63 8.9 1.3 2.0 2 0 0 2 2 2 0 Xrn1 helical domain FHIPEP PF00771.20 CDJ45968.1 - 3.6 5.9 13.5 2.3 6.6 0.9 2.3 2 0 0 2 2 2 0 FHIPEP family FAM91_C PF14648.6 CDJ45968.1 - 4 6.2 12.5 0.92 8.3 2.5 2.1 2 0 0 2 2 2 0 FAM91 C-terminus CBP_BcsG PF11658.8 CDJ45968.1 - 4 5.7 17.7 3 6.2 8.0 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG Gti1_Pac2 PF09729.9 CDJ45968.1 - 4.1 7.5 25.0 1.3 9.1 1.8 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family DUF853 PF05872.12 CDJ45968.1 - 4.6 5.7 22.6 0.29 9.7 2.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Bul1_N PF04425.12 CDJ45968.1 - 4.7 5.9 21.5 3.4 6.3 11.1 2.0 2 0 0 2 2 2 0 Bul1 N terminus DUF1764 PF08576.10 CDJ45968.1 - 4.8 8.2 27.2 1.7 9.6 3.9 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF1980 PF09323.10 CDJ45968.1 - 5.1 7.0 19.2 1.3 8.9 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Ribosomal_S2 PF00318.20 CDJ45968.1 - 5.2 6.2 13.2 0.33 10.2 0.5 2.2 2 0 0 2 2 2 0 Ribosomal protein S2 Hydin_ADK PF17213.3 CDJ45968.1 - 5.3 7.3 19.6 7.4 6.8 1.8 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain FYDLN_acid PF09538.10 CDJ45968.1 - 5.7 7.7 24.2 3.4 8.4 12.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RR_TM4-6 PF06459.12 CDJ45968.1 - 6.1 6.6 34.3 4.3 7.1 6.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CDJ45968.1 - 6.6 3.7 23.7 0.3 8.2 11.4 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Exonuc_VII_L PF02601.15 CDJ45968.1 - 8.6 5.8 26.2 6.2 6.3 12.1 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit PPL5 PF18168.1 CDJ45968.1 - 8.7 5.5 21.4 6.2 6.0 11.2 2.1 2 0 0 2 2 2 0 Prim-pol family 5 YABBY PF04690.13 CDJ45968.1 - 9 6.8 21.3 4.6 7.8 0.8 2.2 2 0 0 2 2 2 0 YABBY protein PRP1_N PF06424.12 CDJ45968.1 - 9 6.7 28.4 2.2 8.7 5.1 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal XRCC4 PF06632.12 CDJ45968.1 - 9 5.0 27.3 0.24 10.2 2.5 2.1 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Pannexin_like PF12534.8 CDJ45968.1 - 9.2 5.2 21.2 4.1 6.4 10.4 2.1 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 HNOBA PF07701.14 CDJ45968.1 - 9.3 5.6 19.5 1.7 8.0 1.5 2.2 2 0 0 2 2 2 0 Heme NO binding associated TFIIA PF03153.13 CDJ45970.1 - 0.0037 17.3 43.3 0.0044 17.1 43.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ45970.1 - 0.0061 16.2 31.3 0.016 14.8 20.7 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 CDJ45970.1 - 0.13 10.6 19.3 0.16 10.2 19.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.11 CDJ45970.1 - 0.31 9.5 19.2 0.34 9.3 19.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.9 CDJ45970.1 - 0.33 9.2 33.0 0.33 9.2 33.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CCSAP PF15748.5 CDJ45970.1 - 0.85 9.7 32.0 1.1 9.4 32.0 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MDM10 PF12519.8 CDJ45970.1 - 1 8.1 15.5 1.2 7.9 15.5 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Apt1 PF10351.9 CDJ45970.1 - 1.4 7.7 19.2 1.6 7.5 19.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 CDJ45970.1 - 1.4 5.9 23.3 1.5 5.9 23.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peroxin-3 PF04882.12 CDJ45970.1 - 1.7 7.6 21.4 1.9 7.4 21.4 1.3 1 0 0 1 1 1 0 Peroxin-3 Hamartin PF04388.12 CDJ45970.1 - 2.4 6.7 20.7 2.4 6.7 20.7 1.2 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 CDJ45970.1 - 2.9 6.5 20.3 2.8 6.5 20.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.9 CDJ45972.1 - 0.0048 16.6 9.0 0.0048 16.6 9.0 5.9 6 1 1 7 7 7 2 Nuclear RNA-splicing-associated protein Nha1_C PF08619.10 CDJ45972.1 - 0.0055 16.0 0.3 0.0055 16.0 0.3 3.6 3 1 0 3 3 3 1 Alkali metal cation/H+ antiporter Nha1 C terminus MMR1 PF08505.10 CDJ45972.1 - 0.012 15.9 14.4 0.012 15.9 14.4 3.6 4 0 0 4 4 4 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 CDJ45972.1 - 1.8 8.4 77.8 0.54 10.2 12.5 3.4 3 1 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Trypan_PARP PF05887.11 CDJ45973.1 - 2.9 7.9 35.7 0.036 14.0 26.6 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) 7TM_GPCR_Srh PF10318.9 CDJ45975.1 - 6 5.8 4.7 6.4 5.7 2.9 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh SR-25 PF10500.9 CDJ45976.1 - 0.044 13.4 35.2 0.1 12.2 35.2 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein MID_MedPIWI PF18296.1 CDJ45976.1 - 0.29 10.9 36.3 0.42 10.4 36.3 1.1 1 0 0 1 1 1 0 MID domain of medPIWI Pinin_SDK_memA PF04696.13 CDJ45976.1 - 2.1 8.4 49.6 2.2 8.4 26.1 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Spt20 PF12090.8 CDJ45977.1 - 0.013 15.2 9.1 0.013 15.2 9.1 5.2 3 2 1 4 4 4 0 Spt20 family MAP7 PF05672.11 CDJ45977.1 - 1 9.0 74.9 0.7 9.6 3.3 3.3 3 0 0 3 3 3 0 MAP7 (E-MAP-115) family RskA PF10099.9 CDJ45978.1 - 0.054 13.8 0.4 0.054 13.8 0.4 9.5 1 1 5 7 7 7 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ45979.1 - 8.1e-05 22.8 34.2 0.0007 19.7 26.7 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit fn3 PF00041.21 CDJ45979.1 - 0.0015 18.9 0.0 0.0015 18.9 0.0 3.3 3 1 1 4 4 3 1 Fibronectin type III domain SR-25 PF10500.9 CDJ45979.1 - 0.0084 15.8 20.7 0.02 14.5 10.9 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CDJ45979.1 - 0.012 16.2 1.0 0.012 16.2 1.0 3.1 2 1 0 2 2 1 0 Dehydrin SPX PF03105.19 CDJ45979.1 - 0.014 15.3 12.3 0.023 14.6 12.3 1.3 1 1 0 1 1 1 0 SPX domain Presenilin PF01080.17 CDJ45979.1 - 0.019 13.7 15.5 0.0085 14.9 5.5 2.0 2 0 0 2 2 2 0 Presenilin Lin-8 PF03353.15 CDJ45979.1 - 0.03 13.9 22.1 0.046 13.3 9.4 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Hydin_ADK PF17213.3 CDJ45979.1 - 0.077 13.3 15.7 0.22 11.8 5.8 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Endostatin PF06482.11 CDJ45979.1 - 0.15 11.5 12.3 0.036 13.5 5.3 2.0 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin EPL1 PF10513.9 CDJ45979.1 - 0.24 11.8 14.0 0.31 11.4 5.8 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Neur_chan_memb PF02932.16 CDJ45979.1 - 0.28 11.2 10.3 1.5 8.8 6.7 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BORG_CEP PF14957.6 CDJ45979.1 - 0.34 12.1 11.7 3.5 8.8 0.7 2.2 2 0 0 2 2 2 0 Cdc42 effector Gti1_Pac2 PF09729.9 CDJ45979.1 - 0.35 10.9 12.2 6.7 6.8 8.0 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Velvet PF11754.8 CDJ45979.1 - 0.37 10.7 16.5 0.083 12.8 6.9 2.1 2 0 0 2 2 2 0 Velvet factor DUF4050 PF13259.6 CDJ45979.1 - 0.45 10.8 16.2 2 8.7 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Methyltransf_32 PF13679.6 CDJ45979.1 - 0.59 10.1 15.6 0.29 11.1 10.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Nha1_C PF08619.10 CDJ45979.1 - 0.85 8.8 18.5 1.4 8.1 2.4 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus PepSY_TM PF03929.16 CDJ45979.1 - 1 9.0 5.3 0.46 10.1 2.4 2.0 2 0 0 2 2 2 0 PepSY-associated TM region DUF1180 PF06679.12 CDJ45979.1 - 1.2 9.6 14.9 4.4 7.7 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SOG2 PF10428.9 CDJ45979.1 - 1.4 8.0 16.7 0.93 8.6 4.8 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein Pex14_N PF04695.13 CDJ45979.1 - 1.6 9.4 34.5 0.45 11.2 22.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIP PF07454.11 CDJ45979.1 - 1.7 8.0 13.6 0.47 9.9 5.9 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TERB2 PF15101.6 CDJ45979.1 - 1.8 8.6 24.2 1.6 8.8 1.0 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Rxt3 PF08642.10 CDJ45979.1 - 2.2 9.1 9.4 1.1 10.0 3.3 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Connexin PF00029.19 CDJ45979.1 - 2.5 7.8 11.0 0.41 10.4 5.1 2.0 2 0 0 2 2 2 0 Connexin CPSF100_C PF13299.6 CDJ45979.1 - 6 7.0 12.1 12 6.1 5.7 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TCP PF03634.13 CDJ45979.1 - 6.3 7.3 18.4 5.8 7.5 10.2 2.2 2 0 0 2 2 2 0 TCP family transcription factor Zip PF02535.22 CDJ45979.1 - 7.6 5.6 11.7 0.5 9.5 3.3 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter DUF719 PF05334.13 CDJ45979.1 - 7.7 6.7 15.2 9.4 6.4 5.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Ctr PF04145.15 CDJ45979.1 - 8.8 6.9 11.1 3.5 8.2 2.8 2.3 2 0 0 2 2 2 0 Ctr copper transporter family PAT1 PF09770.9 CDJ45979.1 - 10 4.3 28.8 0.27 9.5 20.5 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Usp PF00582.26 CDJ45980.1 - 0.027 15.0 2.5 0.029 14.9 1.9 1.3 1 1 0 1 1 1 0 Universal stress protein family FDF PF09532.10 CDJ45980.1 - 0.047 14.6 3.9 0.1 13.5 3.9 1.5 1 1 1 2 2 2 0 FDF domain DUF809 PF05663.11 CDJ45980.1 - 1.3 9.1 6.2 2.4 8.3 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF809) RskA PF10099.9 CDJ45981.1 - 0.0085 16.4 2.9 0.0085 16.4 2.9 2.1 2 0 0 2 2 2 1 Anti-sigma-K factor rskA SPX PF03105.19 CDJ45981.1 - 0.047 13.6 21.1 0.079 12.9 21.1 1.4 1 1 0 1 1 1 0 SPX domain COX6B PF02297.17 CDJ45981.1 - 0.24 11.7 6.4 0.26 11.6 5.3 1.6 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb CHCH PF06747.13 CDJ45981.1 - 0.88 9.8 13.7 11 6.3 12.0 2.8 2 1 0 2 2 2 0 CHCH domain Spt20 PF12090.8 CDJ45981.1 - 1.4 8.5 12.6 0.043 13.4 5.4 1.9 2 0 0 2 2 2 0 Spt20 family Pet191_N PF10203.9 CDJ45981.1 - 8 6.8 10.4 17 5.8 10.4 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 RskA PF10099.9 CDJ45984.1 - 0.43 10.9 0.0 0.091 13.0 12.4 10.0 2 2 6 8 8 8 0 Anti-sigma-K factor rskA LMBR1 PF04791.16 CDJ45984.1 - 0.76 8.6 5.0 0.46 9.3 2.4 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein CDC45 PF02724.14 CDJ45986.1 - 0.33 9.2 14.7 0.4 8.9 14.7 1.3 1 0 0 1 1 1 0 CDC45-like protein CDK5_activator PF03261.15 CDJ45986.1 - 0.75 9.3 14.4 0.95 8.9 14.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein IER PF05760.12 CDJ45986.1 - 1.4 9.2 30.8 2 8.7 30.8 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) SEEEED PF14797.6 CDJ45986.1 - 1.4 9.1 12.1 3.5 7.8 3.8 2.4 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Afi1 PF07792.12 CDJ45986.1 - 1.6 9.2 16.0 6.5 7.2 0.8 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking AAA_23 PF13476.6 CDJ45986.1 - 2.3 8.7 24.7 3.5 8.1 24.7 1.2 1 0 0 1 1 1 0 AAA domain Spore_YhcN_YlaJ PF09580.10 CDJ45986.1 - 2.6 8.1 17.4 2.2 8.4 8.7 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) NST1 PF13945.6 CDJ45986.1 - 2.6 8.1 26.2 0.59 10.2 12.9 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator LMBR1 PF04791.16 CDJ45986.1 - 3.4 6.5 10.4 3.8 6.3 10.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Mitofilin PF09731.9 CDJ45986.1 - 5.9 5.6 44.7 3.1 6.5 3.0 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Arf PF00025.21 CDJ45987.1 - 0.0012 18.3 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CRT10 PF08728.10 CDJ45988.1 - 2.5 6.2 5.3 3.7 5.6 5.3 1.2 1 0 0 1 1 1 0 CRT10 Arf PF00025.21 CDJ45989.1 - 1.6e-12 47.2 0.0 2.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3784 PF12650.7 CDJ45989.1 - 0.12 12.6 0.0 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) JmjC PF02373.22 CDJ45990.1 - 9e-20 71.2 0.0 9e-20 71.2 0.0 3.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 CDJ45990.1 - 0.0005 20.0 0.0 0.00089 19.2 0.0 1.4 1 0 0 1 1 1 1 jmjN domain SR-25 PF10500.9 CDJ45990.1 - 0.36 10.4 36.6 0.11 12.1 17.3 3.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein HEAT PF02985.22 CDJ45991.1 - 0.014 15.6 1.7 0.34 11.3 0.0 4.5 3 0 0 3 3 3 0 HEAT repeat Arm PF00514.23 CDJ45991.1 - 0.13 12.3 1.8 11 6.2 0.0 4.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF3439 PF11921.8 CDJ45993.1 - 1.1 9.2 6.1 4.1 7.4 6.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RskA PF10099.9 CDJ45993.1 - 3.2 8.0 32.5 0.15 12.3 11.5 4.6 4 0 0 4 4 4 0 Anti-sigma-K factor rskA PT PF04886.12 CDJ45994.1 - 0.00085 18.8 2.9 0.0023 17.5 2.9 1.7 1 0 0 1 1 1 1 PT repeat NFACT-R_1 PF05670.13 CDJ45995.1 - 0.064 13.9 2.5 0.21 12.2 2.5 2.0 1 0 0 1 1 1 0 NFACT protein RNA binding domain zf-CDGSH PF09360.10 CDJ45996.1 - 6.6e-10 39.0 0.1 3.4e-09 36.8 0.1 2.3 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type TFIIA PF03153.13 CDJ45997.1 - 4.3e-06 27.0 34.9 6.5e-06 26.4 34.9 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3807 PF12720.7 CDJ45997.1 - 0.00011 22.6 20.0 0.00014 22.2 20.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) CCSAP PF15748.5 CDJ45997.1 - 0.00012 22.3 21.7 0.00018 21.8 21.7 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated DUF913 PF06025.12 CDJ45997.1 - 0.00042 19.4 7.9 0.00053 19.1 7.9 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Endostatin PF06482.11 CDJ45997.1 - 0.00056 19.5 12.8 0.00065 19.3 12.8 1.3 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin TFIIF_alpha PF05793.12 CDJ45997.1 - 0.00067 18.4 11.5 0.00084 18.1 11.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA_11 PF13086.6 CDJ45997.1 - 0.001 18.9 13.6 0.0013 18.6 13.6 1.2 1 0 0 1 1 1 1 AAA domain Presenilin PF01080.17 CDJ45997.1 - 0.0012 17.7 23.2 0.0016 17.3 23.2 1.2 1 0 0 1 1 1 1 Presenilin BAF1_ABF1 PF04684.13 CDJ45997.1 - 0.0014 17.8 11.1 0.0017 17.5 11.1 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor PTPRCAP PF15713.5 CDJ45997.1 - 0.0031 17.8 22.5 0.0057 16.9 22.5 1.6 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated LAP1C PF05609.12 CDJ45997.1 - 0.0039 16.4 15.0 0.0043 16.2 15.0 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) RskA PF10099.9 CDJ45997.1 - 0.0045 17.3 7.7 0.0045 17.3 7.7 2.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Band_3_cyto PF07565.13 CDJ45997.1 - 0.0063 16.4 14.9 0.0087 15.9 14.9 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain DUF4746 PF15928.5 CDJ45997.1 - 0.0063 16.0 14.6 0.0082 15.6 14.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) PAT1 PF09770.9 CDJ45997.1 - 0.0074 14.6 28.6 0.0086 14.4 28.6 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 CobT PF06213.12 CDJ45997.1 - 0.0076 15.7 33.8 0.014 14.8 33.8 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT SLC12 PF03522.15 CDJ45997.1 - 0.009 15.1 18.1 0.01 14.9 18.1 1.1 1 0 0 1 1 1 1 Solute carrier family 12 DUF5427 PF10310.9 CDJ45997.1 - 0.013 14.5 21.5 0.015 14.3 21.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) TRAP_alpha PF03896.16 CDJ45997.1 - 0.015 14.5 7.7 0.026 13.7 7.7 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4776 PF16003.5 CDJ45997.1 - 0.015 14.3 12.6 0.016 14.2 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) SART-1 PF03343.13 CDJ45997.1 - 0.016 13.8 22.7 0.02 13.5 22.7 1.1 1 0 0 1 1 1 0 SART-1 family eIF-3_zeta PF05091.12 CDJ45997.1 - 0.02 13.9 24.7 0.024 13.7 24.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GAGA_bind PF06217.12 CDJ45997.1 - 0.025 14.9 10.9 0.027 14.8 10.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 CDJ45997.1 - 0.027 14.3 22.7 0.039 13.8 22.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 CDJ45997.1 - 0.028 12.9 20.5 0.032 12.8 20.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF966 PF06136.13 CDJ45997.1 - 0.037 13.8 15.3 0.046 13.4 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SID-1_RNA_chan PF13965.6 CDJ45997.1 - 0.037 12.4 5.9 0.041 12.3 5.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAPS PF04499.15 CDJ45997.1 - 0.051 12.4 12.9 0.057 12.2 12.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PA26 PF04636.13 CDJ45997.1 - 0.055 12.4 11.8 0.06 12.3 11.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2052 PF09747.9 CDJ45997.1 - 0.06 13.5 25.8 0.083 13.0 25.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Neur_chan_memb PF02932.16 CDJ45997.1 - 0.067 13.2 17.2 0.089 12.8 17.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 CDJ45997.1 - 0.069 10.3 19.5 0.077 10.1 19.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAG1-DNAbind PF09271.11 CDJ45997.1 - 0.07 13.8 12.7 0.12 13.0 12.7 1.4 1 0 0 1 1 1 0 LAG1, DNA binding CDC45 PF02724.14 CDJ45997.1 - 0.075 11.3 24.4 0.095 11.0 24.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Serinc PF03348.15 CDJ45997.1 - 0.076 11.9 10.0 0.095 11.6 10.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CBP_BcsG PF11658.8 CDJ45997.1 - 0.12 10.7 11.1 0.16 10.4 11.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG PIP5K PF01504.18 CDJ45997.1 - 0.12 11.6 14.9 0.17 11.1 14.9 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CSG2 PF16965.5 CDJ45997.1 - 0.12 11.3 10.3 0.16 10.9 10.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Afi1 PF07792.12 CDJ45997.1 - 0.14 12.6 18.7 0.24 11.9 18.7 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF1387 PF07139.11 CDJ45997.1 - 0.14 11.8 21.3 0.21 11.3 21.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Peptidase_S15 PF02129.18 CDJ45997.1 - 0.16 11.6 10.0 0.21 11.2 10.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Pex14_N PF04695.13 CDJ45997.1 - 0.16 12.6 28.9 0.065 13.9 25.7 1.9 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S64 PF08192.11 CDJ45997.1 - 0.19 10.1 20.2 0.019 13.5 16.3 1.3 2 0 0 2 2 1 0 Peptidase family S64 Tim54 PF11711.8 CDJ45997.1 - 0.2 10.4 20.1 0.26 10.0 20.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2151 PF10221.9 CDJ45997.1 - 0.2 10.2 13.7 0.24 9.9 13.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator XRN_M PF17846.1 CDJ45997.1 - 0.21 10.5 12.9 0.27 10.1 12.9 1.1 1 0 0 1 1 1 0 Xrn1 helical domain V_ATPase_I PF01496.19 CDJ45997.1 - 0.22 9.4 22.6 0.28 9.0 22.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 CDJ45997.1 - 0.28 9.8 15.7 0.38 9.4 15.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 CDJ45997.1 - 0.28 10.0 16.2 0.4 9.5 16.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 CDJ45997.1 - 0.32 10.4 11.4 0.36 10.2 11.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Smg8_Smg9 PF10220.9 CDJ45997.1 - 0.4 8.9 18.2 0.47 8.7 18.2 1.1 1 0 0 1 1 1 0 Smg8_Smg9 FAM60A PF15396.6 CDJ45997.1 - 0.45 10.5 16.5 0.69 9.9 16.5 1.4 1 0 0 1 1 1 0 Protein Family FAM60A TCP PF03634.13 CDJ45997.1 - 0.49 10.9 27.4 0.4 11.2 26.3 1.4 1 1 0 1 1 1 0 TCP family transcription factor DUF2828 PF11443.8 CDJ45997.1 - 0.54 8.3 21.3 0.7 7.9 21.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Rrn6 PF10214.9 CDJ45997.1 - 0.55 8.7 33.7 0.69 8.3 33.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CKAP2_C PF15297.6 CDJ45997.1 - 0.67 9.0 19.1 0.88 8.6 19.1 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus NST1 PF13945.6 CDJ45997.1 - 0.67 10.0 31.2 1.1 9.4 31.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Dicty_REP PF05086.12 CDJ45997.1 - 0.68 7.8 13.0 0.8 7.6 13.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Gti1_Pac2 PF09729.9 CDJ45997.1 - 0.7 10.0 19.1 1.2 9.2 19.1 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Sec62 PF03839.16 CDJ45997.1 - 0.86 9.1 18.2 1.1 8.7 18.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 MDM10 PF12519.8 CDJ45997.1 - 0.86 8.4 18.2 1.2 8.0 18.2 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Membralin PF09746.9 CDJ45997.1 - 0.88 8.5 14.5 1.1 8.2 14.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein NPR3 PF03666.13 CDJ45997.1 - 0.92 8.2 24.2 1.2 7.9 24.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GPCR_chapero_1 PF11904.8 CDJ45997.1 - 1.3 8.4 13.2 1.7 8.0 13.2 1.2 1 0 0 1 1 1 0 GPCR-chaperone Asp-B-Hydro_N PF05279.11 CDJ45997.1 - 1.3 9.0 20.7 1.7 8.7 20.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Rtf2 PF04641.12 CDJ45997.1 - 1.4 8.3 20.2 2 7.7 20.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Otopetrin PF03189.13 CDJ45997.1 - 1.5 7.6 10.0 1.9 7.2 10.0 1.2 1 0 0 1 1 1 0 Otopetrin UPF0560 PF10577.9 CDJ45997.1 - 1.6 7.1 29.2 2.6 6.4 29.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4638 PF15472.6 CDJ45997.1 - 1.6 8.4 18.2 2.1 8.0 18.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Scs3p PF10261.9 CDJ45997.1 - 1.8 8.0 4.5 2.5 7.5 4.5 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF3295 PF11702.8 CDJ45997.1 - 1.9 7.7 26.7 0.018 14.4 19.1 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3295) Spore_coat_CotO PF14153.6 CDJ45997.1 - 2.4 8.0 31.3 4.1 7.3 31.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Hid1 PF12722.7 CDJ45997.1 - 2.5 6.1 23.1 3 5.9 23.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PBP1_TM PF14812.6 CDJ45997.1 - 2.7 8.4 11.8 5.9 7.3 11.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CCDC53 PF10152.9 CDJ45997.1 - 3 8.2 27.3 0.55 10.6 23.3 1.8 2 0 0 2 2 1 0 Subunit CCDC53 of WASH complex DUF4366 PF14283.6 CDJ45997.1 - 3.4 7.7 12.3 6.3 6.8 12.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Paramyxo_ncap PF00973.19 CDJ45997.1 - 3.7 6.4 21.4 4.7 6.0 21.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Raftlin PF15250.6 CDJ45997.1 - 3.8 6.1 19.9 5.3 5.7 19.9 1.2 1 0 0 1 1 1 0 Raftlin SRP-alpha_N PF04086.13 CDJ45997.1 - 4.2 7.2 26.1 6.9 6.5 26.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Baculo_PP31 PF05311.11 CDJ45997.1 - 4.4 6.7 17.1 6.7 6.1 17.1 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) AF-4 PF05110.13 CDJ45997.1 - 4.5 5.2 34.1 0.0037 15.4 21.9 1.7 2 0 0 2 2 1 0 AF-4 proto-oncoprotein CLN3 PF02487.17 CDJ45997.1 - 5 6.1 18.6 7 5.6 18.6 1.2 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 CDJ45997.1 - 5.1 5.8 20.8 6.6 5.4 20.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Mem_trans PF03547.18 CDJ45997.1 - 5.5 5.3 8.0 6.9 5.0 8.0 1.2 1 0 0 1 1 1 0 Membrane transport protein API5 PF05918.11 CDJ45997.1 - 5.8 5.6 22.3 8 5.1 22.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) NARP1 PF12569.8 CDJ45997.1 - 7.2 5.4 22.9 10 4.9 22.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CAF1 PF04857.20 CDJ45997.1 - 7.8 5.6 14.8 10 5.2 14.8 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease MCM_bind PF09739.9 CDJ45997.1 - 8.3 4.7 22.6 11 4.3 22.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor HCO3_cotransp PF00955.21 CDJ45997.1 - 8.6 5.1 8.9 11 4.7 8.9 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF3292 PF11696.8 CDJ45997.1 - 9.3 4.5 14.9 12 4.2 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) FYDLN_acid PF09538.10 CDJ45997.1 - 9.4 7.0 20.4 2.1 9.1 16.7 1.7 2 0 0 2 2 1 0 Protein of unknown function (FYDLN_acid) SR-25 PF10500.9 CDJ45997.1 - 9.7 5.7 32.8 4.6 6.8 19.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cellulose_synt PF03552.14 CDJ45997.1 - 9.8 4.5 10.7 12 4.3 10.7 1.1 1 0 0 1 1 1 0 Cellulose synthase Chorion_2 PF03964.15 CDJ45998.1 - 5.9 7.8 12.5 14 6.6 5.7 2.6 2 0 0 2 2 2 0 Chorion family 2 MFS_1 PF07690.16 CDJ45999.1 - 2.2e-13 49.9 2.8 5.7e-11 41.9 0.0 3.1 3 0 0 3 3 3 1 Major Facilitator Superfamily DUF2722 PF10846.8 CDJ45999.1 - 0.0038 16.2 8.0 0.0038 16.2 8.0 3.2 2 1 0 2 2 1 1 Protein of unknown function (DUF2722) FHIPEP PF00771.20 CDJ45999.1 - 0.0065 15.0 17.2 0.076 11.5 8.6 2.2 2 0 0 2 2 2 2 FHIPEP family Peptidase_S49_N PF08496.10 CDJ45999.1 - 0.014 15.5 4.1 0.014 15.5 4.1 3.2 2 1 1 3 3 2 0 Peptidase family S49 N-terminal MMR1 PF08505.10 CDJ45999.1 - 0.02 15.2 24.3 0.031 14.6 2.1 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Velvet PF11754.8 CDJ45999.1 - 0.039 13.9 12.4 0.18 11.7 0.5 2.3 2 0 0 2 2 2 0 Velvet factor SID-1_RNA_chan PF13965.6 CDJ45999.1 - 0.051 12.0 3.0 0.3 9.5 0.6 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TCP PF03634.13 CDJ45999.1 - 0.16 12.5 0.0 0.16 12.5 0.0 3.4 2 1 1 3 3 3 0 TCP family transcription factor Neur_chan_memb PF02932.16 CDJ45999.1 - 0.68 10.0 16.9 2.1 8.3 2.9 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.16 CDJ45999.1 - 0.72 8.7 7.7 2.8 6.7 0.1 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein Presenilin PF01080.17 CDJ45999.1 - 4.4 6.0 28.2 0.72 8.6 5.0 2.3 2 0 0 2 2 2 0 Presenilin Lin-8 PF03353.15 CDJ45999.1 - 7.3 6.0 28.2 0.31 10.6 2.7 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Mit_ribos_Mrp51 PF11709.8 CDJ45999.1 - 9.3 5.7 21.2 5.7 6.4 2.9 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit Presenilin PF01080.17 CDJ46000.1 - 0.016 14.0 5.6 0.017 13.9 5.6 1.1 1 0 0 1 1 1 0 Presenilin DUF3013 PF11217.8 CDJ46000.1 - 0.068 13.0 0.4 0.068 13.0 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3013) cwf18 PF08315.12 CDJ46000.1 - 0.67 10.6 10.1 0.89 10.2 10.1 1.3 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Ndc1_Nup PF09531.10 CDJ46000.1 - 1.7 7.2 7.0 1.9 7.1 7.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PIP5K PF01504.18 CDJ46000.1 - 4.1 6.5 6.2 5.1 6.2 6.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Folliculin PF11704.8 CDJ46000.1 - 4.6 7.1 6.3 6.2 6.7 6.3 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4834 PF16118.5 CDJ46000.1 - 5 8.1 17.0 1.1 10.3 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SARAF PF06682.12 CDJ46000.1 - 5.7 6.5 13.4 8 6.0 13.4 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis V_ATPase_I PF01496.19 CDJ46000.1 - 6.6 4.5 8.6 8.4 4.2 8.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4175 PF13779.6 CDJ46000.1 - 9.6 4.0 37.7 16 3.3 37.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4175) YIF1 PF03878.15 CDJ46001.1 - 2.3e-05 24.0 0.2 0.015 14.9 0.0 2.3 2 0 0 2 2 2 2 YIF1 Glyco_hydro_100 PF12899.7 CDJ46001.1 - 0.015 14.0 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 Alkaline and neutral invertase Yip1 PF04893.17 CDJ46001.1 - 0.038 13.7 22.0 0.04 13.6 17.3 2.9 2 1 1 3 3 3 0 Yip1 domain MKRN1_C PF15815.5 CDJ46001.1 - 0.04 14.3 0.2 0.15 12.5 0.2 2.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase makorin-1, C-terminal V_ATPase_I PF01496.19 CDJ46001.1 - 0.25 9.2 0.8 0.44 8.4 0.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XRCC4 PF06632.12 CDJ46001.1 - 0.62 8.9 2.8 1.4 7.7 2.8 1.5 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4736 PF15883.5 CDJ46001.1 - 2.8 7.6 6.7 3.6 7.3 1.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4736) Las1 PF04031.13 CDJ46002.1 - 1.5e-36 125.8 0.9 1.5e-36 125.8 0.9 6.0 4 3 0 4 4 4 1 Las1-like DUF2722 PF10846.8 CDJ46002.1 - 2.2e-06 26.9 6.0 2.2e-06 26.9 6.0 11.5 8 4 1 10 10 10 3 Protein of unknown function (DUF2722) Caldesmon PF02029.15 CDJ46002.1 - 0.0011 17.8 10.6 0.0011 17.8 10.6 5.9 5 2 0 5 5 5 1 Caldesmon DUF4207 PF13904.6 CDJ46002.1 - 0.0011 18.7 50.5 0.0011 18.7 50.5 9.2 7 4 1 8 8 8 1 Domain of unknown function (DUF4207) TFIIA PF03153.13 CDJ46003.1 - 3.4e-05 24.0 30.0 6.4e-05 23.1 12.0 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ46003.1 - 0.00021 20.0 11.0 0.00021 20.0 11.0 3.0 2 1 0 2 2 1 1 Macoilin family GAGA_bind PF06217.12 CDJ46003.1 - 0.0076 16.6 4.8 0.0076 16.6 4.8 2.4 2 1 0 2 2 2 1 GAGA binding protein-like family SOG2 PF10428.9 CDJ46003.1 - 0.0089 15.3 42.4 0.2 10.8 11.4 2.1 2 0 0 2 2 2 2 RAM signalling pathway protein CytochromB561_N PF09786.9 CDJ46003.1 - 0.026 13.6 32.4 0.017 14.1 12.3 2.2 2 0 0 2 2 2 0 Cytochrome B561, N terminal SLC12 PF03522.15 CDJ46003.1 - 0.08 12.0 13.6 0.029 13.4 5.7 2.4 2 0 0 2 2 2 0 Solute carrier family 12 LptF_LptG PF03739.14 CDJ46003.1 - 0.093 11.6 0.4 0.2 10.5 0.4 1.5 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF2244 PF10003.9 CDJ46003.1 - 0.16 11.6 8.0 0.22 11.2 1.9 2.4 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF755 PF05501.11 CDJ46003.1 - 3.8 7.8 79.7 0.08 13.2 3.8 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF755) Peptidase_S49_N PF08496.10 CDJ46003.1 - 6.4 6.8 11.4 19 5.3 8.4 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF572 PF04502.13 CDJ46003.1 - 6.4 6.3 29.6 3.1 7.3 12.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) V_ATPase_I PF01496.19 CDJ46003.1 - 6.9 4.4 11.4 0.27 9.1 5.4 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GREB1 PF15782.5 CDJ46003.1 - 7.6 3.5 35.3 0.046 10.8 11.9 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Utp14 PF04615.13 CDJ46003.1 - 8.6 4.8 29.1 2.3 6.7 9.3 2.1 2 0 0 2 2 2 0 Utp14 protein Pol_alpha_B_N PF08418.10 CDJ46003.1 - 8.8 6.2 27.0 4.7 7.1 8.9 2.5 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal YfhO PF09586.10 CDJ46003.1 - 9.8 4.3 7.6 26 2.9 5.3 2.0 2 0 0 2 2 2 0 Bacterial membrane protein YfhO 2-oxoacid_dh PF00198.23 CDJ46004.1 - 7.1e-32 110.7 0.0 1.1e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDJ46004.1 - 1.8e-05 24.5 1.4 2.9e-05 23.8 1.4 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme MAM33 PF02330.16 CDJ46004.1 - 0.00014 21.8 1.4 0.00014 21.8 1.4 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein EPL1 PF10513.9 CDJ46004.1 - 0.00027 21.4 3.3 0.0003 21.2 3.3 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like TERB2 PF15101.6 CDJ46004.1 - 0.00059 19.9 6.7 0.00072 19.7 6.7 1.3 1 0 0 1 1 1 1 Telomere-associated protein TERB2 DDHD PF02862.17 CDJ46004.1 - 0.0011 19.2 2.6 0.0011 19.2 2.6 1.1 1 0 0 1 1 1 1 DDHD domain Spt20 PF12090.8 CDJ46004.1 - 0.0017 18.0 26.1 0.0023 17.6 26.1 1.2 1 0 0 1 1 1 1 Spt20 family DUF4628 PF15429.6 CDJ46004.1 - 0.003 17.3 3.1 0.0036 17.0 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4628) Presenilin PF01080.17 CDJ46004.1 - 0.0041 15.9 5.6 0.0041 15.9 5.6 1.1 1 0 0 1 1 1 1 Presenilin SpoIIP PF07454.11 CDJ46004.1 - 0.0042 16.6 4.2 0.0045 16.5 4.2 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DUF4471 PF14740.6 CDJ46004.1 - 0.0051 16.1 3.1 0.0051 16.1 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) UPF0560 PF10577.9 CDJ46004.1 - 0.0054 15.3 13.0 0.0079 14.8 13.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 eIF-3_zeta PF05091.12 CDJ46004.1 - 0.009 15.0 11.3 0.011 14.7 11.3 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex14_N PF04695.13 CDJ46004.1 - 0.011 16.4 10.1 0.014 16.1 10.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C PF13299.6 CDJ46004.1 - 0.011 15.9 5.7 0.016 15.4 5.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FHIPEP PF00771.20 CDJ46004.1 - 0.019 13.5 2.3 0.023 13.2 2.3 1.2 1 0 0 1 1 1 0 FHIPEP family CCDC53 PF10152.9 CDJ46004.1 - 0.024 15.0 6.8 0.036 14.5 6.8 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Gti1_Pac2 PF09729.9 CDJ46004.1 - 0.026 14.6 3.2 0.031 14.3 3.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family BRF1 PF07741.13 CDJ46004.1 - 0.032 14.6 9.8 0.057 13.8 9.8 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4175 PF13779.6 CDJ46004.1 - 0.033 12.1 17.0 0.038 11.9 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.14 CDJ46004.1 - 0.039 13.9 9.5 0.052 13.5 9.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.10 CDJ46004.1 - 0.04 12.6 19.0 0.046 12.4 19.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ46004.1 - 0.044 13.8 23.0 0.057 13.4 23.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EMC3_TMCO1 PF01956.16 CDJ46004.1 - 0.063 13.0 5.3 0.082 12.6 5.3 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CLN3 PF02487.17 CDJ46004.1 - 0.085 11.9 2.6 0.092 11.8 2.6 1.2 1 0 0 1 1 1 0 CLN3 protein OATP PF03137.20 CDJ46004.1 - 0.095 11.0 1.7 0.098 10.9 1.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Plasmodium_Vir PF05795.11 CDJ46004.1 - 0.1 12.0 3.1 0.12 11.7 3.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein OAD_gamma PF04277.13 CDJ46004.1 - 0.14 12.7 1.1 0.36 11.4 1.1 1.7 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain PepSY_TM PF03929.16 CDJ46004.1 - 0.15 11.7 0.5 0.16 11.6 0.5 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Ub-Mut7C PF14451.6 CDJ46004.1 - 0.16 11.8 0.4 0.58 10.0 0.0 2.1 2 1 1 3 3 1 0 Mut7-C ubiquitin MMR1 PF08505.10 CDJ46004.1 - 0.18 12.1 11.5 0.24 11.7 11.5 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Bud13 PF09736.9 CDJ46004.1 - 0.21 12.0 12.9 0.31 11.4 12.9 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2828 PF11443.8 CDJ46004.1 - 0.23 9.5 6.8 0.31 9.1 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CobT PF06213.12 CDJ46004.1 - 0.29 10.5 14.8 0.38 10.1 14.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4834 PF16118.5 CDJ46004.1 - 0.3 12.1 11.3 0.47 11.4 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ46004.1 - 0.35 10.5 4.6 0.58 9.8 4.6 1.4 1 0 0 1 1 1 0 FAM176 family MPM1 PF17234.2 CDJ46004.1 - 0.42 10.8 11.1 0.67 10.2 11.1 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 AIF_C PF14721.6 CDJ46004.1 - 0.45 10.9 6.5 0.63 10.4 6.5 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Roughex PF06020.11 CDJ46004.1 - 0.45 9.6 14.3 0.63 9.1 14.3 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF913 PF06025.12 CDJ46004.1 - 0.47 9.4 8.7 0.62 9.0 8.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PAT1 PF09770.9 CDJ46004.1 - 0.5 8.6 16.9 0.54 8.5 16.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Connexin PF00029.19 CDJ46004.1 - 0.6 9.8 6.3 0.85 9.3 6.3 1.2 1 0 0 1 1 1 0 Connexin DUF2722 PF10846.8 CDJ46004.1 - 0.83 8.5 29.3 1.1 8.1 29.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FmdE PF02663.14 CDJ46004.1 - 0.88 9.6 4.7 1.4 8.9 4.7 1.3 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Folate_carrier PF01770.18 CDJ46004.1 - 0.9 8.2 5.3 1.3 7.7 5.3 1.2 1 0 0 1 1 1 0 Reduced folate carrier V_ATPase_I PF01496.19 CDJ46004.1 - 1.1 7.1 9.5 1.3 6.8 9.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Band_3_cyto PF07565.13 CDJ46004.1 - 1.4 8.7 9.3 1.8 8.3 9.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain LRRC37AB_C PF14914.6 CDJ46004.1 - 1.6 8.7 12.4 2.6 8.0 12.4 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain EIIBC-GUT_N PF03612.14 CDJ46004.1 - 1.9 8.2 9.5 2.7 7.7 9.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Sec62 PF03839.16 CDJ46004.1 - 2.2 7.7 6.8 2.9 7.3 6.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Ureide_permease PF07168.11 CDJ46004.1 - 3.3 6.4 5.8 4.5 5.9 5.7 1.3 1 1 0 1 1 1 0 Ureide permease DUF4407 PF14362.6 CDJ46004.1 - 4.2 6.6 11.7 5.8 6.2 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMEM51 PF15345.6 CDJ46004.1 - 4.8 6.9 12.9 8.2 6.2 12.9 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 ALMT PF11744.8 CDJ46004.1 - 4.9 5.9 11.0 6.4 5.5 11.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 CDJ46004.1 - 6.3 6.8 9.1 8.4 6.4 9.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Kei1 PF08552.11 CDJ46004.1 - 6.3 6.6 7.4 8.9 6.1 7.4 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RR_TM4-6 PF06459.12 CDJ46004.1 - 8.4 6.1 13.9 11 5.8 13.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RskA PF10099.9 CDJ46005.1 - 0.023 15.0 3.9 0.025 14.9 3.9 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Ketoacyl-synt_2 PF13723.6 CDJ46005.1 - 0.068 12.8 5.3 0.073 12.7 5.3 1.0 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain PET117 PF15786.5 CDJ46005.1 - 0.4 11.0 10.5 0.46 10.8 10.5 1.1 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial TFIIA PF03153.13 CDJ46005.1 - 1.2 9.0 15.6 1.3 9.0 15.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ46005.1 - 2.7 7.5 20.2 3.1 7.3 20.2 1.1 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ46006.1 - 0.093 11.5 13.6 0.11 11.3 13.6 1.0 1 0 0 1 1 1 0 Presenilin Tristanin_u2 PF16638.5 CDJ46006.1 - 0.13 13.1 11.5 0.18 12.6 11.5 1.2 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers Gti1_Pac2 PF09729.9 CDJ46006.1 - 0.15 12.1 9.2 0.19 11.8 9.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Sec62 PF03839.16 CDJ46006.1 - 0.21 11.1 12.3 0.24 10.9 12.3 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S46 PF10459.9 CDJ46006.1 - 0.26 9.9 11.5 0.31 9.7 11.5 1.0 1 0 0 1 1 1 0 Peptidase S46 Ndc1_Nup PF09531.10 CDJ46006.1 - 0.93 8.1 11.5 1 8.0 11.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 CDJ46006.1 - 0.99 8.6 3.6 1 8.5 3.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PCRF PF03462.18 CDJ46006.1 - 1.3 8.8 15.8 1.6 8.5 15.8 1.1 1 0 0 1 1 1 0 PCRF domain DUF3492 PF11997.8 CDJ46006.1 - 1.5 8.5 7.9 1.7 8.3 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) STELLO PF03385.17 CDJ46006.1 - 1.6 7.5 10.8 2.1 7.1 10.8 1.2 1 0 0 1 1 1 0 STELLO glycosyltransferases FAM60A PF15396.6 CDJ46006.1 - 1.6 8.7 8.8 2 8.4 8.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Exonuc_VII_L PF02601.15 CDJ46006.1 - 2.3 7.7 20.8 2.7 7.5 20.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RR_TM4-6 PF06459.12 CDJ46006.1 - 3 7.6 13.8 3.4 7.4 13.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MDM10 PF12519.8 CDJ46006.1 - 3.2 6.5 15.7 3.8 6.3 15.7 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PAT1 PF09770.9 CDJ46006.1 - 3.5 5.8 30.8 3.9 5.6 30.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Membralin PF09746.9 CDJ46006.1 - 4 6.4 10.7 4.7 6.1 10.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein K_trans PF02705.16 CDJ46006.1 - 4.1 5.8 9.1 5 5.5 9.1 1.0 1 0 0 1 1 1 0 K+ potassium transporter DUF3332 PF11810.8 CDJ46006.1 - 4.2 7.0 8.9 5.3 6.7 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Radical_SAM_N PF08497.10 CDJ46006.1 - 5.8 6.1 8.3 7.5 5.7 8.3 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal Spt20 PF12090.8 CDJ46008.1 - 0.0026 17.4 52.7 0.0087 15.7 17.2 2.3 2 0 0 2 2 2 2 Spt20 family DDRGK PF09756.9 CDJ46008.1 - 4.9 6.7 18.3 1.9 8.1 8.0 2.3 2 0 0 2 2 2 0 DDRGK domain PNISR PF15996.5 CDJ46008.1 - 6.3 7.0 49.2 2.9 8.1 17.5 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR MAT1 PF06391.13 CDJ46008.1 - 8.8 6.1 36.9 0.068 13.0 12.8 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 PVL_ORF50 PF07768.11 CDJ46009.1 - 7.4 6.9 13.2 0.22 11.8 1.7 2.2 1 1 1 2 2 2 0 PVL ORF-50-like family RskA PF10099.9 CDJ46010.1 - 0.001 19.4 10.7 0.0013 19.1 10.7 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ46010.1 - 0.008 16.2 6.7 0.011 15.8 6.7 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ46010.1 - 0.47 10.0 10.7 0.56 9.8 10.7 1.1 1 0 0 1 1 1 0 Spt20 family DivIC PF04977.15 CDJ46010.1 - 7.2 6.5 9.9 10 6.0 9.9 1.1 1 0 0 1 1 1 0 Septum formation initiator SR-25 PF10500.9 CDJ46012.1 - 0.00053 19.7 6.9 0.00053 19.7 6.9 11.8 9 1 2 11 11 11 3 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ46012.1 - 0.18 12.1 0.0 0.18 12.1 0.0 13.9 3 3 6 9 9 9 0 Anti-sigma-K factor rskA Apt1 PF10351.9 CDJ46013.1 - 0.99 8.2 21.0 1.1 8.0 21.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4813 PF16072.5 CDJ46013.1 - 1.1 8.8 23.4 1.3 8.6 23.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) SOG2 PF10428.9 CDJ46013.1 - 1.5 7.9 33.2 1.5 7.9 33.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein NST1 PF13945.6 CDJ46013.1 - 2.1 8.4 14.9 2.9 8.0 14.9 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator BAF1_ABF1 PF04684.13 CDJ46013.1 - 2.2 7.3 16.5 2.5 7.0 16.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ46013.1 - 2.8 6.6 12.0 3.2 6.4 12.0 1.1 1 0 0 1 1 1 0 Presenilin RIFIN PF02009.16 CDJ46013.1 - 3.1 7.6 9.4 3.8 7.3 9.4 1.2 1 0 0 1 1 1 0 Rifin ALMT PF11744.8 CDJ46013.1 - 4.6 6.0 8.5 5.1 5.8 8.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PPP4R2 PF09184.11 CDJ46013.1 - 5 6.6 15.6 5.4 6.5 15.6 1.0 1 0 0 1 1 1 0 PPP4R2 Raftlin PF15250.6 CDJ46013.1 - 5.6 5.6 9.1 5.8 5.5 9.1 1.1 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.13 CDJ46013.1 - 6.3 5.5 11.8 7.2 5.3 11.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Lin-8 PF03353.15 CDJ46013.1 - 7.1 6.1 9.1 10 5.6 9.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SCHIP-1 PF10148.9 CDJ46013.1 - 8.6 5.9 10.0 12 5.5 10.0 1.3 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Peptidase_S64 PF08192.11 CDJ46013.1 - 9 4.6 20.8 9.5 4.6 20.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 CDJ46013.1 - 9.5 3.2 16.7 10 3.1 16.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer IMUP PF15761.5 CDJ46016.1 - 0.00078 20.1 25.3 0.0099 16.6 11.2 2.5 2 0 0 2 2 2 2 Immortalisation up-regulated protein DUF755 PF05501.11 CDJ46016.1 - 0.0098 16.2 26.0 0.37 11.1 12.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF755) DUF2681 PF10883.8 CDJ46016.1 - 0.068 13.6 8.3 0.64 10.5 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TFIIF_alpha PF05793.12 CDJ46016.1 - 0.17 10.5 12.2 0.22 10.1 12.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1635 PF07795.11 CDJ46016.1 - 0.31 10.9 9.8 2.6 7.9 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Presenilin PF01080.17 CDJ46016.1 - 1.3 7.7 11.1 1.8 7.2 11.1 1.3 1 0 0 1 1 1 0 Presenilin Pap_E4 PF02711.14 CDJ46016.1 - 1.3 10.0 5.5 2.2 9.3 0.4 2.3 2 0 0 2 2 2 0 E4 protein DUF572 PF04502.13 CDJ46016.1 - 6 6.4 12.7 7.7 6.0 12.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.16 CDJ46016.1 - 7.1 6.6 9.4 11 6.0 9.5 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF966 PF06136.13 CDJ46016.1 - 8.5 6.0 15.8 11 5.7 15.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SR-25 PF10500.9 CDJ46016.1 - 9.4 5.8 37.0 0.67 9.5 16.0 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ46017.1 - 9e-10 39.1 11.5 1.3e-05 25.6 0.0 12.2 2 1 5 8 8 8 3 Anti-sigma-K factor rskA Adaptin_binding PF10199.9 CDJ46017.1 - 0.0023 18.5 0.0 0.0023 18.5 0.0 9.4 2 2 1 3 3 3 1 Alpha and gamma adaptin binding protein p34 zf-C2HC5 PF06221.13 CDJ46017.1 - 0.079 13.0 6.2 3.6 7.6 6.2 2.8 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type TFIIA PF03153.13 CDJ46018.1 - 1e-05 25.8 12.7 1e-05 25.8 12.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Borrelia_P83 PF05262.11 CDJ46018.1 - 1.9e-05 23.4 0.9 1.9e-05 23.4 0.9 1.0 1 0 0 1 1 1 1 Borrelia P83/100 protein Neur_chan_memb PF02932.16 CDJ46018.1 - 0.0053 16.8 0.4 0.0053 16.8 0.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 CDJ46018.1 - 0.083 12.2 11.6 0.1 12.0 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CPSF100_C PF13299.6 CDJ46018.1 - 0.098 12.8 8.2 0.14 12.3 8.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 CDJ46018.1 - 0.1 11.6 4.7 0.13 11.2 4.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.6 CDJ46018.1 - 0.16 10.3 0.0 0.16 10.3 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EOS1 PF12326.8 CDJ46018.1 - 0.22 11.4 0.5 0.25 11.3 0.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein DDHD PF02862.17 CDJ46018.1 - 0.4 10.8 7.3 0.51 10.5 7.3 1.1 1 0 0 1 1 1 0 DDHD domain Pex14_N PF04695.13 CDJ46018.1 - 0.45 11.2 15.5 0.79 10.4 15.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4192 PF13830.6 CDJ46018.1 - 0.64 10.0 7.7 1 9.3 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) OmpH PF03938.14 CDJ46018.1 - 0.66 10.3 34.4 1.1 9.5 34.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HemX PF04375.14 CDJ46018.1 - 0.68 9.2 30.9 0.88 8.8 30.9 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Pal1 PF08316.11 CDJ46018.1 - 1.4 9.7 5.3 2.2 9.0 5.3 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein Asp-B-Hydro_N PF05279.11 CDJ46018.1 - 2 8.4 15.3 2.9 7.9 15.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF775 PF05603.12 CDJ46018.1 - 4.2 6.8 12.8 5.7 6.4 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) baeRF_family10 PF18854.1 CDJ46018.1 - 4.3 7.6 17.5 2.6 8.3 14.2 2.0 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 eIF-3_zeta PF05091.12 CDJ46018.1 - 6.2 5.7 17.6 7.1 5.5 17.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 CDJ46018.1 - 7.6 6.4 16.5 10 6.0 16.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Lin-8 PF03353.15 CDJ46018.1 - 7.7 6.0 20.4 10 5.6 20.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ndc1_Nup PF09531.10 CDJ46018.1 - 8.4 5.0 8.1 10 4.7 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PPL5 PF18168.1 CDJ46018.1 - 8.9 5.5 11.1 11 5.2 11.1 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF2722 PF10846.8 CDJ46019.1 - 5e-06 25.7 2.0 5e-06 25.7 2.0 16.5 9 5 4 14 14 14 2 Protein of unknown function (DUF2722) DUF3995 PF13160.6 CDJ46020.1 - 0.0027 18.1 3.7 0.0048 17.3 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3995) TFIIA PF03153.13 CDJ46020.1 - 0.0056 16.7 23.3 0.0066 16.5 23.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ46020.1 - 0.32 11.6 7.9 0.6 10.7 7.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein TraG_N PF07916.11 CDJ46020.1 - 1 8.1 10.6 1.4 7.7 10.6 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2722 PF10846.8 CDJ46020.1 - 5.5 5.8 18.9 0.14 11.1 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Patched PF02460.18 CDJ46021.1 - 2.8e-34 118.4 0.0 6.1e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CDJ46021.1 - 7.6e-24 84.3 2.0 2.4e-23 82.7 2.0 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation SID-1_RNA_chan PF13965.6 CDJ46021.1 - 0.54 8.6 0.0 0.54 8.6 0.0 3.3 3 1 0 3 3 3 0 dsRNA-gated channel SID-1 SUIM_assoc PF16619.5 CDJ46022.1 - 9.3 6.4 0.0 9.3 6.4 0.0 5.6 4 2 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF3138 PF11336.8 CDJ46025.1 - 0.13 10.9 3.5 0.36 9.4 3.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PALP PF00291.25 CDJ46026.1 - 8.2e-49 166.6 1.4 1.7e-48 165.6 1.4 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HECT PF00632.25 CDJ46027.1 - 1.3e-79 267.9 0.0 1.9e-79 267.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NAM-associated PF14303.6 CDJ46028.1 - 1.1 9.9 0.0 1.1 9.9 0.0 18.3 12 7 5 17 17 17 0 No apical meristem-associated C-terminal domain AAA_23 PF13476.6 CDJ46029.1 - 0.00071 20.1 0.4 0.00071 20.1 0.4 3.2 3 0 0 3 3 3 1 AAA domain DUF1980 PF09323.10 CDJ46029.1 - 0.017 15.0 0.4 0.017 15.0 0.4 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF1980) Serinc PF03348.15 CDJ46029.1 - 0.025 13.5 0.1 0.025 13.5 0.1 3.2 3 0 0 3 3 2 0 Serine incorporator (Serinc) Afi1 PF07792.12 CDJ46029.1 - 0.04 14.4 8.7 0.15 12.5 0.1 3.0 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SID-1_RNA_chan PF13965.6 CDJ46029.1 - 0.054 11.9 0.5 0.58 8.5 0.0 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 MecA PF05389.12 CDJ46029.1 - 0.15 11.7 10.1 0.26 10.9 0.3 2.6 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) PIP5K PF01504.18 CDJ46029.1 - 0.32 10.2 0.0 0.32 10.2 0.0 2.4 2 1 0 2 2 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Spt20 PF12090.8 CDJ46029.1 - 0.42 10.2 77.0 0.1 12.2 17.0 3.1 3 0 0 3 3 3 0 Spt20 family CLN3 PF02487.17 CDJ46029.1 - 0.95 8.4 11.5 0.46 9.5 0.1 2.6 3 0 0 3 3 3 0 CLN3 protein Connexin PF00029.19 CDJ46029.1 - 1.2 8.9 9.6 0.47 10.2 0.1 2.6 3 0 0 3 3 3 0 Connexin EOS1 PF12326.8 CDJ46029.1 - 1.2 9.0 9.2 1.9e+02 1.9 9.2 2.7 1 1 0 1 1 1 0 N-glycosylation protein RIC3 PF15361.6 CDJ46029.1 - 1.6 9.2 12.3 0.29 11.5 0.1 3.0 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 RskA PF10099.9 CDJ46029.1 - 2.2 8.5 79.5 0.94 9.7 18.9 4.7 2 2 1 3 3 3 0 Anti-sigma-K factor rskA SPX PF03105.19 CDJ46029.1 - 4.4 7.1 24.9 3.2e+03 -2.3 24.9 2.8 1 1 0 1 1 1 0 SPX domain ORC_WH_C PF18137.1 CDJ46029.1 - 6.2 6.9 21.0 0.039 14.0 1.1 3.1 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal DUF4834 PF16118.5 CDJ46029.1 - 9.8 7.2 33.3 2.9 8.9 9.8 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 CDJ46030.1 - 0.0061 15.9 0.3 0.0061 15.9 0.3 4.4 2 2 1 3 3 3 2 Protein kinase domain Spt20 PF12090.8 CDJ46030.1 - 0.013 15.1 20.5 0.013 15.1 20.5 5.4 2 1 2 4 4 4 0 Spt20 family Tetraspanin PF00335.20 CDJ46030.1 - 0.036 13.8 8.4 2.4 7.8 0.0 4.3 3 2 1 4 4 4 0 Tetraspanin family VIR_N PF15912.5 CDJ46030.1 - 5 6.6 17.2 9.1 5.8 11.8 2.3 2 0 0 2 2 2 0 Virilizer, N-terminal TFIIA PF03153.13 CDJ46031.1 - 0.026 14.6 105.8 0.11 12.4 61.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ46031.1 - 0.28 10.2 44.4 0.92 8.5 22.6 2.2 2 0 0 2 2 2 0 Solute carrier family 12 SAGA-Tad1 PF12767.7 CDJ46031.1 - 1.4 8.6 37.6 2.7 7.7 18.5 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit ALMT PF11744.8 CDJ46031.1 - 4.4 6.0 40.7 0.98 8.2 8.9 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter FAM76 PF16046.5 CDJ46031.1 - 5.2 6.3 42.6 5 6.4 18.9 2.3 2 0 0 2 2 2 0 FAM76 protein Zip PF02535.22 CDJ46031.1 - 6.8 5.8 34.3 1.1 8.4 11.6 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Smg8_Smg9 PF10220.9 CDJ46031.1 - 8.4 4.6 42.1 1.5 7.0 10.9 2.1 2 0 0 2 2 2 0 Smg8_Smg9 TFIIA PF03153.13 CDJ46032.1 - 6.6 6.6 11.7 7.5 6.4 11.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CDJ46035.1 - 0.4 9.6 70.6 1 8.3 70.6 1.7 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CryBP1 PF07029.11 CDJ46037.1 - 0.2 11.7 0.7 52 3.9 0.0 2.9 1 1 2 3 3 3 0 CryBP1 protein Ribosomal_L34 PF00468.17 CDJ46037.1 - 0.79 9.7 11.8 5.8 7.0 0.4 4.4 4 0 0 4 4 4 0 Ribosomal protein L34 Nucleo_P87 PF07267.11 CDJ46037.1 - 5.9 5.6 9.6 7.1 5.3 9.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3824 PF12868.7 CDJ46038.1 - 0.0014 19.3 3.3 0.0014 19.3 3.3 18.0 18 3 1 19 19 19 2 Domain of unknwon function (DUF3824) Sec7_N PF12783.7 CDJ46038.1 - 0.056 13.4 1.4 0.65 9.9 0.8 3.1 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Activator_LAG-3 PF11498.8 CDJ46040.1 - 0.81 8.6 36.0 0.89 8.5 36.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ46041.1 - 4.6e-05 23.6 22.5 4.9e-05 23.5 22.5 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ZZ PF00569.17 CDJ46041.1 - 0.00029 20.6 1.3 0.00066 19.4 1.3 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type CDC45 PF02724.14 CDJ46041.1 - 0.00093 17.6 6.0 0.001 17.5 6.0 1.0 1 0 0 1 1 1 1 CDC45-like protein eIF3_subunit PF08597.10 CDJ46041.1 - 0.0021 18.0 8.9 0.0021 18.0 8.9 1.4 2 0 0 2 2 1 1 Translation initiation factor eIF3 subunit RRN3 PF05327.11 CDJ46041.1 - 0.0024 16.5 4.1 0.0026 16.4 4.1 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DDHD PF02862.17 CDJ46041.1 - 0.0031 17.7 2.7 0.0043 17.2 2.7 1.4 1 0 0 1 1 1 1 DDHD domain FAM60A PF15396.6 CDJ46041.1 - 0.0099 15.9 5.2 0.015 15.3 5.2 1.2 1 0 0 1 1 1 1 Protein Family FAM60A DUF913 PF06025.12 CDJ46041.1 - 0.032 13.2 4.5 0.037 13.0 4.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CAF1 PF04857.20 CDJ46041.1 - 0.056 12.6 5.8 0.073 12.2 5.8 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Presenilin PF01080.17 CDJ46041.1 - 0.07 11.9 16.9 0.087 11.6 16.9 1.1 1 0 0 1 1 1 0 Presenilin PPL5 PF18168.1 CDJ46041.1 - 0.14 11.4 9.2 0.17 11.1 9.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 CSG2 PF16965.5 CDJ46041.1 - 0.15 11.0 2.8 0.16 10.9 2.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Otopetrin PF03189.13 CDJ46041.1 - 0.17 10.7 1.1 0.16 10.7 1.1 1.1 1 0 0 1 1 1 0 Otopetrin SID-1_RNA_chan PF13965.6 CDJ46041.1 - 0.22 9.9 0.9 0.22 9.9 0.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ46041.1 - 0.23 11.5 10.5 0.3 11.1 10.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ46041.1 - 0.28 11.0 15.1 0.36 10.6 15.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 CDJ46041.1 - 0.33 8.8 15.2 0.37 8.7 15.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OATP PF03137.20 CDJ46041.1 - 0.35 9.1 1.3 0.45 8.7 1.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SARAF PF06682.12 CDJ46041.1 - 0.41 10.3 13.4 0.52 9.9 13.4 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4813 PF16072.5 CDJ46041.1 - 0.45 10.1 18.4 0.65 9.6 18.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) FancD2 PF14631.6 CDJ46041.1 - 0.47 7.8 6.4 0.57 7.5 6.4 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF2828 PF11443.8 CDJ46041.1 - 0.47 8.5 11.7 0.56 8.2 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RNA_pol_Rpc4 PF05132.14 CDJ46041.1 - 0.5 10.8 14.2 0.63 10.5 13.4 1.5 2 0 0 2 2 1 0 RNA polymerase III RPC4 Tim54 PF11711.8 CDJ46041.1 - 0.51 9.1 13.2 0.67 8.7 13.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.13 CDJ46041.1 - 0.53 9.0 13.9 0.64 8.7 13.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 CDJ46041.1 - 0.57 9.9 7.6 0.84 9.4 7.6 1.3 1 0 0 1 1 1 0 Connexin Gti1_Pac2 PF09729.9 CDJ46041.1 - 0.58 10.2 11.0 0.72 9.9 11.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family CLN3 PF02487.17 CDJ46041.1 - 0.69 8.9 9.1 0.88 8.6 9.1 1.1 1 0 0 1 1 1 0 CLN3 protein DUF2370 PF10176.9 CDJ46041.1 - 0.74 9.4 6.7 0.95 9.1 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) NARP1 PF12569.8 CDJ46041.1 - 0.78 8.6 13.2 0.95 8.3 13.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CobT PF06213.12 CDJ46041.1 - 0.8 9.0 29.6 1.3 8.4 29.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Band_3_cyto PF07565.13 CDJ46041.1 - 0.8 9.5 9.6 1.1 9.0 9.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex14_N PF04695.13 CDJ46041.1 - 0.95 10.1 20.7 0.25 12.0 17.1 1.8 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SLC12 PF03522.15 CDJ46041.1 - 1.1 8.3 14.8 1.3 8.0 14.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.11 CDJ46041.1 - 1.4 8.3 16.6 2.1 7.7 16.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Med19 PF10278.9 CDJ46041.1 - 1.5 8.7 10.5 2 8.3 10.5 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Spore_coat_CotO PF14153.6 CDJ46041.1 - 1.5 8.7 23.4 2.8 7.8 23.4 1.4 1 0 0 1 1 1 0 Spore coat protein CotO TRAP_alpha PF03896.16 CDJ46041.1 - 1.5 7.9 9.9 2 7.6 9.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ndc1_Nup PF09531.10 CDJ46041.1 - 1.8 7.2 7.2 2.2 6.8 7.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ALMT PF11744.8 CDJ46041.1 - 1.9 7.2 9.5 2.2 7.0 9.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF5580 PF17743.1 CDJ46041.1 - 2.1 6.8 13.4 2.5 6.5 13.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) CBP_BcsG PF11658.8 CDJ46041.1 - 2.1 6.7 11.4 2.7 6.3 11.4 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG BORG_CEP PF14957.6 CDJ46041.1 - 2.1 9.5 11.5 3 9.0 11.5 1.2 1 0 0 1 1 1 0 Cdc42 effector PA26 PF04636.13 CDJ46041.1 - 2.4 7.0 9.9 3 6.7 9.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PIP5K PF01504.18 CDJ46041.1 - 4.6 6.4 11.8 6.1 6.0 11.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Hamartin PF04388.12 CDJ46041.1 - 4.8 5.7 12.5 6.1 5.4 12.5 1.1 1 0 0 1 1 1 0 Hamartin protein CemA PF03040.14 CDJ46041.1 - 5.2 6.9 4.7 6.7 6.6 4.7 1.0 1 0 0 1 1 1 0 CemA family SAPS PF04499.15 CDJ46041.1 - 6.3 5.5 12.8 7.7 5.2 12.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAT1 PF09770.9 CDJ46041.1 - 6.4 4.9 26.6 7.8 4.6 26.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rtf2 PF04641.12 CDJ46041.1 - 7.2 5.9 14.6 10 5.4 14.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger O-antigen_lig PF13425.6 CDJ46041.1 - 7.7 5.2 7.1 9 5.0 7.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF2126 PF09899.9 CDJ46041.1 - 9.1 4.2 10.5 11 3.9 10.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) TCP PF03634.13 CDJ46041.1 - 9.3 6.8 18.1 13 6.4 18.1 1.1 1 0 0 1 1 1 0 TCP family transcription factor CCSAP PF15748.5 CDJ46041.1 - 9.6 6.3 20.4 13 5.9 20.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Lin-8 PF03353.15 CDJ46041.1 - 9.8 5.6 19.4 12 5.3 19.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CDJ46042.1 - 0.0029 17.3 11.1 0.0029 17.3 11.1 15.2 7 4 4 12 12 12 2 Spt20 family DUF2207 PF09972.9 CDJ46042.1 - 0.87 8.3 5.2 0.17 10.7 0.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) S1 PF00575.23 CDJ46043.1 - 0.00025 21.3 0.2 1.7 9.0 0.1 3.3 3 0 0 3 3 3 2 S1 RNA binding domain U3_snoRNA_assoc PF08297.11 CDJ46043.1 - 0.14 12.9 0.1 0.14 12.9 0.1 7.5 6 2 0 6 6 6 0 U3 snoRNA associated DUF4834 PF16118.5 CDJ46043.1 - 0.19 12.7 0.2 0.19 12.7 0.2 8.3 6 3 1 7 7 7 0 Domain of unknown function (DUF4834) SR-25 PF10500.9 CDJ46044.1 - 0.00034 20.3 7.9 0.00034 20.3 7.9 3.5 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein DASH_Spc19 PF08287.11 CDJ46044.1 - 0.002 18.0 13.2 0.002 18.0 13.2 4.3 4 1 0 4 4 4 1 Spc19 RskA PF10099.9 CDJ46044.1 - 0.018 15.3 11.4 0.018 15.3 11.4 7.0 1 1 5 6 6 6 0 Anti-sigma-K factor rskA LURAP PF14854.6 CDJ46044.1 - 0.089 12.7 0.1 0.089 12.7 0.1 2.2 3 0 0 3 3 3 0 Leucine rich adaptor protein DUF4401 PF14351.6 CDJ46044.1 - 1.9 7.8 7.4 1.4 8.1 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) FlaC_arch PF05377.11 CDJ46044.1 - 8 6.9 7.4 15 6.1 1.6 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SR-25 PF10500.9 CDJ46045.1 - 0.00079 19.1 13.3 0.00079 19.1 13.3 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ46045.1 - 0.46 10.4 11.5 0.68 9.8 11.5 1.3 1 0 0 1 1 1 0 SPX domain Smg8_Smg9 PF10220.9 CDJ46045.1 - 4.6 5.4 14.7 6.2 5.0 14.7 1.1 1 0 0 1 1 1 0 Smg8_Smg9 DUF1635 PF07795.11 CDJ46045.1 - 5.8 6.7 17.6 9.6 6.0 17.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) PIP5K PF01504.18 CDJ46046.1 - 0.0027 17.0 0.3 0.0041 16.4 0.3 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EPL1 PF10513.9 CDJ46046.1 - 0.0039 17.6 7.3 0.1 13.0 0.9 2.3 2 0 0 2 2 2 2 Enhancer of polycomb-like Spore_YhcN_YlaJ PF09580.10 CDJ46046.1 - 0.012 15.7 1.5 0.021 14.9 1.5 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) RPA43_OB PF17875.1 CDJ46046.1 - 0.014 16.0 6.0 0.027 15.1 0.1 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I MACPF PF01823.19 CDJ46046.1 - 0.064 13.3 2.4 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 MAC/Perforin domain DUF4834 PF16118.5 CDJ46046.1 - 0.14 13.1 8.6 1.4 9.9 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) eIF-3_zeta PF05091.12 CDJ46046.1 - 0.22 10.4 9.4 1.7 7.5 2.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2722 PF10846.8 CDJ46046.1 - 0.28 10.1 18.1 1.1 8.2 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ46046.1 - 0.79 9.3 29.9 1.6 8.3 10.6 2.2 2 0 0 2 2 2 0 Spt20 family LapA_dom PF06305.11 CDJ46046.1 - 0.82 9.5 0.0 0.82 9.5 0.0 3.1 2 1 0 2 2 1 0 Lipopolysaccharide assembly protein A domain DUF702 PF05142.12 CDJ46046.1 - 1.5 9.3 8.8 4 7.9 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) MAGE PF01454.19 CDJ46046.1 - 2.5 7.7 12.5 0.072 12.8 2.1 2.2 2 0 0 2 2 2 0 MAGE family EphA2_TM PF14575.6 CDJ46046.1 - 2.9 8.9 3.8 21 6.1 0.1 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain AIF_C PF14721.6 CDJ46046.1 - 6.2 7.2 6.3 6.2 7.2 0.4 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3446 PF11928.8 CDJ46047.1 - 0.076 13.3 6.5 0.18 12.1 6.5 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain Spt20 PF12090.8 CDJ46047.1 - 0.093 12.3 12.7 0.2 11.2 12.7 1.5 1 0 0 1 1 1 0 Spt20 family DUF4207 PF13904.6 CDJ46047.1 - 0.1 12.3 12.3 0.077 12.7 8.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Sec16 PF12932.7 CDJ46047.1 - 0.12 13.0 6.0 0.081 13.5 1.7 2.5 2 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region DUF4834 PF16118.5 CDJ46047.1 - 0.21 12.6 2.6 0.4 11.7 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) AF-4 PF05110.13 CDJ46047.1 - 0.9 7.5 13.5 0.012 13.8 1.8 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ46047.1 - 7 6.2 19.3 0.75 9.4 10.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ46049.1 - 5.7e-05 23.5 7.5 7.1e-05 23.2 7.5 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Nop53 PF07767.11 CDJ46049.1 - 0.0012 18.3 9.6 0.0016 17.9 9.6 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) TCP PF03634.13 CDJ46049.1 - 0.0024 18.5 8.3 0.0031 18.1 8.3 1.1 1 0 0 1 1 1 1 TCP family transcription factor CCSAP PF15748.5 CDJ46049.1 - 0.008 16.4 15.5 0.012 15.8 15.5 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated FAM199X PF15814.5 CDJ46049.1 - 0.0083 15.2 9.2 0.01 14.9 9.2 1.1 1 0 0 1 1 1 1 Protein family FAM199X DUF4603 PF15376.6 CDJ46049.1 - 0.02 12.3 7.6 0.023 12.1 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Med15 PF09606.10 CDJ46049.1 - 0.02 13.6 21.5 0.022 13.5 21.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3682 PF12446.8 CDJ46049.1 - 0.022 15.3 21.5 0.03 14.8 21.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) EOS1 PF12326.8 CDJ46049.1 - 0.028 14.3 1.3 0.033 14.1 1.3 1.1 1 0 0 1 1 1 0 N-glycosylation protein DDHD PF02862.17 CDJ46049.1 - 0.038 14.2 6.0 0.049 13.8 6.0 1.2 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ46049.1 - 0.04 12.9 7.0 0.041 12.9 7.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.6 CDJ46049.1 - 0.053 11.5 18.0 0.055 11.4 18.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SprA-related PF12118.8 CDJ46049.1 - 0.15 11.2 20.4 0.19 10.8 20.4 1.2 1 0 0 1 1 1 0 SprA-related family Neur_chan_memb PF02932.16 CDJ46049.1 - 0.22 11.6 3.2 0.24 11.4 3.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ46049.1 - 0.3 9.8 9.3 0.33 9.7 9.3 1.1 1 0 0 1 1 1 0 Presenilin THOC2_N PF16134.5 CDJ46049.1 - 0.33 9.5 6.4 0.41 9.2 6.4 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus RR_TM4-6 PF06459.12 CDJ46049.1 - 0.59 9.9 7.5 0.66 9.7 7.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Orf78 PF06024.12 CDJ46049.1 - 0.96 9.8 4.5 1.9 8.9 4.5 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Ndc1_Nup PF09531.10 CDJ46049.1 - 1 7.9 12.8 1.2 7.7 12.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RAP1 PF07218.11 CDJ46049.1 - 1.2 7.3 4.2 1.3 7.2 4.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SpoIIP PF07454.11 CDJ46049.1 - 2 7.8 9.8 3.3 7.1 9.8 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF1360 PF07098.11 CDJ46049.1 - 3 7.9 4.5 9 6.3 4.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Eapp_C PF10238.9 CDJ46049.1 - 3.4 7.7 17.5 1.6 8.8 15.3 1.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein FHIPEP PF00771.20 CDJ46049.1 - 4.1 5.7 5.8 5.8 5.3 5.8 1.1 1 0 0 1 1 1 0 FHIPEP family DUF3464 PF11947.8 CDJ46049.1 - 5.4 6.8 12.4 9.5 6.0 12.4 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CTP_transf_1 PF01148.20 CDJ46050.1 - 1e-10 41.8 5.0 0.011 15.6 0.3 3.5 3 0 0 3 3 3 3 Cytidylyltransferase family Pex14_N PF04695.13 CDJ46050.1 - 0.0024 18.6 6.9 0.0024 18.6 6.9 6.2 5 2 1 6 6 6 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ46050.1 - 0.0048 16.5 28.8 0.022 14.4 1.0 3.3 3 0 0 3 3 3 3 Spt20 family SR-25 PF10500.9 CDJ46050.1 - 0.0088 15.7 7.7 0.0088 15.7 7.7 4.2 6 0 0 6 6 6 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ46050.1 - 0.032 14.5 0.0 0.032 14.5 0.0 11.8 2 2 4 6 6 6 0 Anti-sigma-K factor rskA TNV_CP PF03898.13 CDJ46050.1 - 0.12 11.6 0.5 0.71 9.1 0.5 2.4 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein Apt1 PF10351.9 CDJ46050.1 - 0.4 9.5 7.6 0.61 8.9 2.0 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF2722 PF10846.8 CDJ46050.1 - 3.3 6.6 28.6 0.15 10.9 0.5 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ46051.1 - 0.00043 20.4 10.4 0.00056 20.0 10.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ46051.1 - 0.18 11.7 21.1 0.25 11.2 21.1 1.2 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 CDJ46051.1 - 0.85 8.2 9.3 1.2 7.8 9.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Roughex PF06020.11 CDJ46051.1 - 3.7 6.6 5.5 5.2 6.1 5.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Med15 PF09606.10 CDJ46051.1 - 4.7 5.8 24.1 5.2 5.6 24.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ46052.1 - 0.032 13.8 27.5 0.034 13.8 27.5 1.1 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 CDJ46052.1 - 0.034 14.8 15.3 0.034 14.8 15.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RMP PF14996.6 CDJ46052.1 - 0.049 13.9 5.4 0.059 13.6 5.4 1.1 1 0 0 1 1 1 0 Retinal Maintenance TFIIA PF03153.13 CDJ46052.1 - 0.097 12.7 27.7 0.1 12.6 27.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 CDJ46052.1 - 0.44 10.7 5.2 0.48 10.6 5.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 CDJ46052.1 - 0.55 9.6 8.1 0.53 9.7 8.1 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2722 PF10846.8 CDJ46052.1 - 0.62 8.9 22.2 0.65 8.9 22.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CobT PF06213.12 CDJ46052.1 - 0.8 9.0 12.3 0.79 9.1 12.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TERB2 PF15101.6 CDJ46052.1 - 0.86 9.6 11.9 0.9 9.6 11.9 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CCDC53 PF10152.9 CDJ46052.1 - 1 9.8 11.4 1.1 9.6 11.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF5327 PF17261.2 CDJ46052.1 - 1.1 10.0 14.7 1.6 9.5 14.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Conotoxin PF02950.17 CDJ46052.1 - 1.3 10.1 6.1 1.8 9.6 6.1 1.3 1 0 0 1 1 1 0 Conotoxin Presenilin PF01080.17 CDJ46052.1 - 2.1 7.0 10.7 2 7.1 10.7 1.0 1 0 0 1 1 1 0 Presenilin PepSY_TM PF03929.16 CDJ46052.1 - 2.3 7.8 5.8 2.3 7.8 5.8 1.1 1 0 0 1 1 1 0 PepSY-associated TM region DUF2367 PF10164.9 CDJ46052.1 - 2.4 8.7 6.2 2.9 8.4 6.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Suf PF05843.14 CDJ46052.1 - 2.4 8.1 12.7 2.5 8.0 12.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 CDJ46052.1 - 2.5 7.0 13.4 2.8 6.8 13.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.10 CDJ46052.1 - 3.1 6.4 8.0 2.9 6.5 8.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MMR1 PF08505.10 CDJ46052.1 - 3.5 7.8 12.8 3.9 7.7 12.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4834 PF16118.5 CDJ46052.1 - 3.7 8.6 10.6 5.2 8.1 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ46052.1 - 4.3 7.0 6.0 4.7 6.9 6.0 1.1 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 CDJ46052.1 - 4.5 7.0 9.6 4.2 7.1 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1980 PF09323.10 CDJ46052.1 - 4.6 7.1 5.9 4.8 7.0 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PAT1 PF09770.9 CDJ46052.1 - 4.6 5.4 22.1 4.4 5.4 22.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EIIBC-GUT_N PF03612.14 CDJ46052.1 - 4.6 6.9 7.1 5.3 6.8 7.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Dicty_REP PF05086.12 CDJ46052.1 - 5.1 4.9 5.5 5.1 4.9 5.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein THOC2_N PF16134.5 CDJ46052.1 - 5.4 5.5 8.6 6.7 5.2 8.6 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Hid1 PF12722.7 CDJ46052.1 - 6.1 4.8 8.8 6.1 4.8 8.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4175 PF13779.6 CDJ46052.1 - 6.2 4.6 25.6 6.2 4.6 25.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Neur_chan_memb PF02932.16 CDJ46052.1 - 6.4 6.8 8.4 6.5 6.7 8.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ctr PF04145.15 CDJ46052.1 - 6.8 7.3 5.4 8 7.1 5.4 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Androgen_recep PF02166.16 CDJ46052.1 - 6.8 5.4 28.1 7.2 5.3 28.1 1.1 1 0 0 1 1 1 0 Androgen receptor CLN3 PF02487.17 CDJ46052.1 - 9.7 5.1 6.2 10 5.0 6.2 1.0 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 CDJ46052.1 - 9.7 4.9 5.6 9.8 4.9 5.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2722 PF10846.8 CDJ46054.1 - 0.012 14.7 14.6 0.011 14.7 14.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ46054.1 - 0.015 14.9 19.3 0.017 14.7 19.3 1.1 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ46054.1 - 0.071 12.2 9.0 0.071 12.2 9.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ46054.1 - 0.25 11.3 18.8 0.25 11.3 18.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.3 CDJ46054.1 - 0.28 11.4 6.4 0.31 11.3 6.4 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain TERB2 PF15101.6 CDJ46054.1 - 0.31 11.1 6.6 0.34 10.9 6.6 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 eIF-3_zeta PF05091.12 CDJ46054.1 - 0.31 9.9 6.3 0.31 10.0 6.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.6 CDJ46054.1 - 0.33 8.8 13.0 0.31 8.9 13.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4834 PF16118.5 CDJ46054.1 - 0.39 11.7 7.5 0.42 11.6 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) UPF0560 PF10577.9 CDJ46054.1 - 0.41 9.1 8.5 0.41 9.1 8.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Activator_LAG-3 PF11498.8 CDJ46054.1 - 0.49 9.3 19.4 0.52 9.2 19.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF5349 PF17298.2 CDJ46054.1 - 0.76 9.5 10.3 0.85 9.3 10.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Suf PF05843.14 CDJ46054.1 - 1.2 9.1 10.9 1.2 9.1 10.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ46054.1 - 1.2 7.8 5.4 1.2 7.8 5.4 1.0 1 0 0 1 1 1 0 Presenilin MscS_TM PF12794.7 CDJ46054.1 - 1.8 7.4 3.9 1.8 7.3 3.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Neur_chan_memb PF02932.16 CDJ46054.1 - 2.2 8.3 5.9 2.4 8.2 5.9 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3043 PF11241.8 CDJ46054.1 - 2.2 8.3 7.3 2.6 8.1 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Med3 PF11593.8 CDJ46054.1 - 2.8 7.1 20.0 3.1 6.9 20.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pex14_N PF04695.13 CDJ46054.1 - 4.5 7.9 16.0 5.1 7.7 16.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Androgen_recep PF02166.16 CDJ46054.1 - 5 5.9 18.9 5.1 5.8 18.9 1.1 1 0 0 1 1 1 0 Androgen receptor SUIM_assoc PF16619.5 CDJ46057.1 - 0.0095 16.0 3.9 0.029 14.4 0.6 2.3 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Methyltr_RsmB-F PF01189.17 CDJ46058.1 - 2.9e-09 36.9 0.2 1.9e-07 30.9 0.1 2.5 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F SUIM_assoc PF16619.5 CDJ46058.1 - 0.0078 16.3 1.4 0.0078 16.3 1.4 4.2 2 1 1 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Neur_chan_memb PF02932.16 CDJ46058.1 - 5.8 6.9 5.5 5.2 7.1 0.6 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Coilin_N PF15862.5 CDJ46058.1 - 8.1 6.3 11.7 4.6 7.0 0.6 2.6 2 0 0 2 2 2 0 Coilin N-terminus EPL1 PF10513.9 CDJ46058.1 - 8.3 6.8 11.9 1.2 9.5 1.7 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like GTP_EFTU PF00009.27 CDJ46059.1 - 8.4e-57 191.9 0.0 1.6e-56 191.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CDJ46059.1 - 1.2e-22 79.8 0.0 6.6e-22 77.4 0.1 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.18 CDJ46059.1 - 2.7e-15 56.2 0.0 1.1e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 CDJ46059.1 - 2.9e-11 43.6 0.0 2.9e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CDJ46059.1 - 1.5e-08 34.6 0.1 3.1e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II AvrPtoB_bdg PF16847.5 CDJ46059.1 - 0.068 13.7 0.0 2.6 8.6 0.0 2.6 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 CDJ46060.1 - 4.3e-12 46.1 0.0 2.1e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ46060.1 - 1.7e-08 34.2 0.2 1.7e-08 34.2 0.2 3.5 4 0 0 4 4 4 2 Elongation factor Tu GTP binding domain TniB PF05621.11 CDJ46060.1 - 4.2e-06 26.3 0.5 0.00031 20.2 0.1 3.3 4 0 0 4 4 4 2 Bacterial TniB protein SDA1 PF05285.12 CDJ46060.1 - 0.0012 18.3 2.8 0.0012 18.3 2.8 4.7 3 1 1 4 4 4 1 SDA1 Sin_N PF04801.13 CDJ46060.1 - 0.0048 16.2 0.0 0.0048 16.2 0.0 4.4 2 1 2 4 4 4 1 Sin-like protein conserved region Speriolin_C PF15059.6 CDJ46060.1 - 0.011 15.9 1.1 0.011 15.9 1.1 3.0 2 1 0 2 2 2 0 Speriolin C-terminus FeoB_N PF02421.18 CDJ46060.1 - 0.043 13.3 5.2 0.44 10.1 0.0 3.1 4 0 0 4 4 4 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDJ46060.1 - 0.14 12.1 18.0 0.23 11.3 0.1 4.4 4 1 1 5 5 5 0 RsgA GTPase Roc PF08477.13 CDJ46060.1 - 0.33 11.2 0.1 0.33 11.2 0.1 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ECH_2 PF16113.5 CDJ46061.1 - 7.3e-69 232.8 0.0 7.3e-69 232.8 0.0 3.7 2 1 1 3 3 3 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CDJ46061.1 - 4.4e-23 81.9 0.0 4.4e-23 81.9 0.0 3.7 4 1 1 5 5 5 1 Enoyl-CoA hydratase/isomerase FA_desaturase PF00487.24 CDJ46061.1 - 0.49 10.2 2.8 0.61 9.9 2.0 1.6 1 1 0 1 1 1 0 Fatty acid desaturase MPM1 PF17234.2 CDJ46061.1 - 4.6 7.5 11.6 10 6.3 7.4 2.5 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 EPL1 PF10513.9 CDJ46061.1 - 7.6 6.9 8.6 5.4 7.4 1.8 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like AF-4 PF05110.13 CDJ46061.1 - 9.4 4.2 28.9 2.7 6.0 4.6 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Pro_isomerase PF00160.21 CDJ46062.1 - 3.6e-47 160.5 0.1 3.6e-47 160.5 0.1 2.2 3 1 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CDJ46062.1 - 4e-09 36.9 0.0 0.32 12.0 0.0 4.4 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ46062.1 - 0.096 13.0 0.0 3.2 8.1 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_3 PF13920.6 CDJ46063.1 - 8.4e-11 41.6 11.3 1.2e-10 41.1 11.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ46063.1 - 0.0001 22.6 10.0 0.00015 22.0 10.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ46063.1 - 0.00018 21.3 10.3 0.00028 20.7 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ46063.1 - 0.00026 20.8 9.8 0.0004 20.2 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ46063.1 - 0.55 10.2 14.3 0.86 9.6 14.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.14 CDJ46063.1 - 0.95 9.2 9.0 2.5 7.9 9.0 1.7 1 1 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.6 CDJ46063.1 - 1.1 9.2 12.5 1.8 8.5 12.5 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 EMP24_GP25L PF01105.24 CDJ46064.1 - 1.9e-38 132.2 0.6 2.2e-38 132.0 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Orf78 PF06024.12 CDJ46064.1 - 0.031 14.6 0.1 0.054 13.8 0.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF2721 PF11026.8 CDJ46064.1 - 0.32 10.9 5.3 0.063 13.2 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF1378 PF07125.11 CDJ46064.1 - 1.4 9.1 5.4 2.9 8.1 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Cyclin PF08613.11 CDJ46065.1 - 3.8e-29 102.1 0.2 7.1e-29 101.2 0.0 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CDJ46065.1 - 2.7e-11 43.3 0.2 4.1e-11 42.7 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain KH_6 PF15985.5 CDJ46066.1 - 5.3e-13 49.1 0.0 9.7e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 KH domain Adeno_PIX PF03955.14 CDJ46066.1 - 0.025 14.8 2.3 0.068 13.3 2.3 1.8 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Methyltransf_16 PF10294.9 CDJ46067.1 - 1.5e-06 28.1 0.1 0.018 14.8 0.2 2.2 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 CDJ46067.1 - 3.2e-05 23.5 0.0 6.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CDJ46067.1 - 0.00024 21.7 0.1 0.011 16.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CDJ46067.1 - 0.00078 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CDJ46067.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ46067.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ46067.1 - 0.025 15.2 0.0 11 6.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ46067.1 - 0.052 13.2 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 DUF2183 PF09949.9 CDJ46068.1 - 0.0017 18.7 0.0 0.0046 17.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) TFIIA PF03153.13 CDJ46068.1 - 0.0045 17.1 6.8 0.0093 16.0 6.8 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ46068.1 - 0.0046 16.0 11.5 0.0086 15.1 11.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ46068.1 - 0.6 10.0 5.1 1.2 9.1 5.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 CDJ46068.1 - 0.61 11.1 2.1 1.6 9.8 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pex14_N PF04695.13 CDJ46068.1 - 3.2 8.4 13.8 1.4 9.5 7.6 2.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NAD_Gly3P_dh_C PF07479.14 CDJ46069.1 - 1.1e-38 132.7 0.1 1.8e-38 132.0 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 CDJ46069.1 - 1.4e-32 112.8 0.0 2.7e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SseB PF07179.12 CDJ46069.1 - 0.013 15.7 0.0 0.05 13.9 0.0 1.8 2 0 0 2 2 2 0 SseB protein N-terminal domain DUF726 PF05277.12 CDJ46069.1 - 0.037 13.0 0.0 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF726) PfkB PF00294.24 CDJ46070.1 - 1.4e-43 149.3 1.8 2.6e-37 128.8 0.3 2.5 2 1 0 2 2 2 2 pfkB family carbohydrate kinase HEAT PF02985.22 CDJ46071.1 - 9e-05 22.4 19.4 0.32 11.3 0.0 7.8 7 0 0 7 7 7 2 HEAT repeat Importin_rep_6 PF18829.1 CDJ46071.1 - 0.0012 18.9 0.0 0.0035 17.5 0.0 1.7 1 0 0 1 1 1 1 Importin repeat 6 RIX1 PF08167.12 CDJ46071.1 - 0.0015 18.3 3.0 0.17 11.6 0.1 4.3 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis NopRA1 PF16201.5 CDJ46071.1 - 0.0017 18.0 3.9 9.3 5.8 0.3 4.8 3 2 1 4 4 4 2 Nucleolar pre-ribosomal-associated protein 1 HEAT_2 PF13646.6 CDJ46071.1 - 0.017 15.5 21.0 0.3 11.5 1.0 6.4 6 2 0 7 7 7 0 HEAT repeats DUF4042 PF13251.6 CDJ46071.1 - 0.083 12.6 0.5 0.54 9.9 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 CDJ46071.1 - 0.78 10.3 28.5 1.1 9.9 0.0 8.9 6 3 3 9 9 9 0 HEAT-like repeat HECT PF00632.25 CDJ46073.1 - 1.9e-45 155.7 0.0 3.7e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_4 PF13637.6 CDJ46073.1 - 5.5e-08 33.2 0.6 0.0098 16.5 0.1 4.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ46073.1 - 9.5e-08 32.2 1.2 0.58 10.7 0.1 5.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 CDJ46073.1 - 1.4e-07 32.0 0.0 1.5e-05 25.5 0.0 3.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ46073.1 - 2.7e-06 27.5 0.4 0.9 9.9 0.0 4.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ46073.1 - 0.029 14.9 0.1 20 6.2 0.0 5.0 5 0 0 5 5 5 0 Ankyrin repeat DUF4647 PF15504.6 CDJ46075.1 - 0.0036 16.5 15.4 0.0049 16.0 15.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4647) CRT10 PF08728.10 CDJ46075.1 - 0.16 10.1 4.8 0.16 10.1 4.8 1.0 1 0 0 1 1 1 0 CRT10 Pkinase_fungal PF17667.1 CDJ46075.1 - 0.32 9.7 7.7 0.37 9.5 7.7 1.2 1 0 0 1 1 1 0 Fungal protein kinase AAA_23 PF13476.6 CDJ46075.1 - 1.2 9.6 20.3 0.25 11.8 17.3 1.5 2 0 0 2 2 2 0 AAA domain Noggin PF05806.12 CDJ46075.1 - 1.2 9.0 10.5 2.4 8.0 10.5 1.5 1 0 0 1 1 1 0 Noggin Connexin PF00029.19 CDJ46075.1 - 3.5 7.3 15.7 6.6 6.4 15.7 1.5 1 0 0 1 1 1 0 Connexin FapA PF03961.13 CDJ46075.1 - 4.5 5.8 12.4 5.2 5.6 12.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_PP31 PF05311.11 CDJ46075.1 - 5 6.5 23.4 0.61 9.5 17.2 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) GNAT_acetyltr_2 PF13718.6 CDJ46075.1 - 5.3 6.4 11.8 11 5.4 11.8 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Membralin PF09746.9 CDJ46075.1 - 7.6 5.5 12.3 10 5.1 12.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein Peptidase_S64 PF08192.11 CDJ46075.1 - 8.1 4.8 18.5 9.3 4.6 18.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 DRMBL PF07522.14 CDJ46076.1 - 6.5e-11 42.4 1.2 1.9e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Borrelia_P83 PF05262.11 CDJ46076.1 - 0.32 9.5 11.2 0.41 9.1 11.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Spt20 PF12090.8 CDJ46076.1 - 0.43 10.2 22.8 0.69 9.5 22.8 1.2 1 0 0 1 1 1 0 Spt20 family PA26 PF04636.13 CDJ46076.1 - 0.69 8.8 7.7 0.92 8.4 7.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TFIIA PF03153.13 CDJ46076.1 - 2.3 8.1 18.0 3.4 7.6 18.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.10 CDJ46076.1 - 9.3 6.3 9.7 16 5.5 9.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Roughex PF06020.11 CDJ46076.1 - 9.7 5.2 9.6 15 4.6 9.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Helicase_C PF00271.31 CDJ46077.1 - 1e-15 58.0 0.2 1.2e-14 54.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Macoilin PF09726.9 CDJ46077.1 - 1.8 7.1 29.6 0.31 9.5 8.3 2.4 2 0 0 2 2 2 0 Macoilin family DUF572 PF04502.13 CDJ46077.1 - 3 7.4 25.8 0.64 9.6 20.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Xpo1 PF08389.12 CDJ46077.1 - 7.1 6.7 9.9 1 9.4 5.2 1.9 2 0 0 2 2 2 0 Exportin 1-like protein RRM_1 PF00076.22 CDJ46078.1 - 3.3e-07 30.0 2.4 4.9e-05 23.1 0.1 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CDJ46078.1 - 6.1e-05 23.2 0.1 0.00011 22.3 0.1 1.4 1 0 0 1 1 1 1 RRM-like domain RskA PF10099.9 CDJ46078.1 - 0.00086 19.7 39.4 0.014 15.7 6.3 4.4 1 1 1 2 2 2 1 Anti-sigma-K factor rskA RRM_5 PF13893.6 CDJ46078.1 - 0.0028 17.3 0.1 0.44 10.1 0.0 3.4 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Otopetrin PF03189.13 CDJ46078.1 - 0.13 11.0 0.0 0.44 9.3 0.0 1.8 1 1 0 1 1 1 0 Otopetrin Pex14_N PF04695.13 CDJ46078.1 - 0.14 12.8 60.8 0.98 10.1 25.5 3.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.17 CDJ46078.1 - 0.19 11.9 20.1 0.4 10.8 6.0 2.8 3 0 0 3 3 3 0 DDHD domain EOS1 PF12326.8 CDJ46078.1 - 5 7.0 7.5 2.5 8.0 0.1 2.4 2 0 0 2 2 2 0 N-glycosylation protein Cuticle_3 PF11018.8 CDJ46079.1 - 1.5 9.0 15.9 1.5 9.0 1.5 4.2 1 1 2 4 4 4 0 Pupal cuticle protein C1 Tmemb_cc2 PF10267.9 CDJ46080.1 - 0.0013 17.9 4.8 0.0013 17.9 4.8 3.1 3 0 0 3 3 3 2 Predicted transmembrane and coiled-coil 2 protein SR-25 PF10500.9 CDJ46080.1 - 0.01 15.5 18.4 0.01 15.5 18.4 3.6 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein U1snRNP70_N PF12220.8 CDJ46080.1 - 0.038 14.6 0.7 0.038 14.6 0.7 4.8 3 3 2 5 5 5 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MerR-DNA-bind PF09278.11 CDJ46080.1 - 0.06 13.9 0.2 0.06 13.9 0.2 2.2 2 0 0 2 2 2 0 MerR, DNA binding EELM2 PF15863.5 CDJ46081.1 - 1.2e-32 113.4 0.0 7.2e-22 78.3 0.0 2.3 2 0 0 2 2 2 2 Extended EGL-27 and MTA1 homology domain DUF4667 PF15700.5 CDJ46081.1 - 0.00069 19.8 9.2 0.098 12.7 1.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) Med3 PF11593.8 CDJ46082.1 - 1.5 7.9 13.2 1.9 7.6 13.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Methyltr_RsmF_N PF17125.5 CDJ46083.1 - 0.064 13.7 0.4 0.33 11.5 0.2 2.0 1 1 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF Med13_N PF11597.8 CDJ46083.1 - 0.082 12.3 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Apt1 PF10351.9 CDJ46084.1 - 0.27 10.0 6.4 0.35 9.7 6.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain AF-4 PF05110.13 CDJ46084.1 - 0.3 9.1 21.9 0.37 8.8 21.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SUZ PF12752.7 CDJ46084.1 - 5.5 7.8 14.0 0.24 12.2 6.0 2.6 2 1 0 2 2 2 0 SUZ domain RR_TM4-6 PF06459.12 CDJ46085.1 - 0.58 9.9 24.4 0.75 9.6 24.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NEMP PF10225.9 CDJ46085.1 - 0.6 9.7 10.1 0.74 9.4 10.1 1.2 1 0 0 1 1 1 0 NEMP family eIF-3_zeta PF05091.12 CDJ46085.1 - 0.76 8.7 29.5 0.9 8.4 29.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ46085.1 - 0.82 7.9 40.6 0.89 7.8 40.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.6 CDJ46085.1 - 1.1 7.6 8.4 1.3 7.3 8.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SART-1 PF03343.13 CDJ46085.1 - 1.3 7.5 28.3 1.5 7.3 28.3 1.1 1 0 0 1 1 1 0 SART-1 family Lin-8 PF03353.15 CDJ46085.1 - 1.5 8.3 25.4 1.8 8.0 25.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist VIR_N PF15912.5 CDJ46085.1 - 1.8 8.1 11.6 2 8.0 11.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal SprA-related PF12118.8 CDJ46085.1 - 3.5 6.7 51.0 4.2 6.4 51.0 1.1 1 0 0 1 1 1 0 SprA-related family Sporozoite_P67 PF05642.11 CDJ46085.1 - 3.8 5.5 14.9 5.2 5.0 14.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDK5_activator PF03261.15 CDJ46085.1 - 4 6.9 18.3 4.2 6.8 18.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Draxin PF15550.6 CDJ46085.1 - 4.5 7.1 22.8 5.8 6.7 22.8 1.1 1 0 0 1 1 1 0 Draxin SOBP PF15279.6 CDJ46085.1 - 4.9 7.7 24.3 5.8 7.4 24.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 CDJ46085.1 - 5 5.7 24.1 6 5.4 24.1 1.0 1 0 0 1 1 1 0 Hamartin protein Peptidase_S15 PF02129.18 CDJ46085.1 - 5.3 6.6 22.5 6.4 6.3 22.5 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Neur_chan_memb PF02932.16 CDJ46085.1 - 5.4 7.0 18.3 6.8 6.7 18.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.10 CDJ46085.1 - 5.5 5.5 55.6 6.2 5.4 55.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC45 PF02724.14 CDJ46085.1 - 5.8 5.1 19.7 6.5 4.9 19.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 CDJ46085.1 - 6.1 4.8 19.7 6.5 4.7 19.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Endostatin PF06482.11 CDJ46085.1 - 7.2 6.0 22.2 8.8 5.7 22.2 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Glyoxalase PF00903.25 CDJ46086.1 - 1.5e-25 89.8 0.0 2.6e-16 60.0 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 CDJ46086.1 - 3e-05 23.9 0.3 0.14 12.0 0.1 3.2 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 CDJ46086.1 - 3.3e-05 24.1 0.0 0.021 15.1 0.0 2.9 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 CDJ46086.1 - 0.00012 22.1 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 2 CppA N-terminal CppA_C PF14507.6 CDJ46086.1 - 0.031 15.0 0.2 1.2 9.9 0.0 2.7 3 0 0 3 3 3 0 CppA C-terminal Glyoxalase_6 PF18029.1 CDJ46086.1 - 0.049 14.4 0.0 24 5.8 0.0 2.8 2 1 0 2 2 2 0 Glyoxalase-like domain DUF755 PF05501.11 CDJ46088.1 - 9.1 6.6 25.2 18 5.6 25.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) La PF05383.17 CDJ46090.1 - 2.1e-08 34.1 0.1 3.4e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 La domain DUF3223 PF11523.8 CDJ46091.1 - 2.1e-10 41.3 1.2 2.1e-10 41.3 1.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3223) Mqo PF06039.15 CDJ46092.1 - 0.011 14.3 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) TraT PF05818.12 CDJ46092.1 - 0.065 12.9 2.3 0.073 12.7 2.3 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Tic110 PF16940.5 CDJ46092.1 - 0.18 10.2 3.0 0.16 10.4 3.0 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter SpoIIP PF07454.11 CDJ46093.1 - 0.0015 18.1 20.6 0.0018 17.8 20.6 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CDJ46093.1 - 0.0016 17.3 25.2 0.0018 17.2 25.2 1.0 1 0 0 1 1 1 1 Presenilin DUF3295 PF11702.8 CDJ46093.1 - 0.0017 17.8 19.0 0.0018 17.7 19.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) PPL5 PF18168.1 CDJ46093.1 - 0.0019 17.5 13.9 0.0024 17.2 13.9 1.1 1 0 0 1 1 1 1 Prim-pol family 5 TFIIA PF03153.13 CDJ46093.1 - 0.0022 18.1 55.1 0.0029 17.7 55.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4746 PF15928.5 CDJ46093.1 - 0.0031 17.0 11.9 0.0034 16.9 11.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 CDJ46093.1 - 0.0048 16.7 11.5 0.0062 16.3 11.5 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Spore_coat_CotO PF14153.6 CDJ46093.1 - 0.0056 16.6 27.9 0.0059 16.6 27.9 1.2 1 0 0 1 1 1 1 Spore coat protein CotO CobT PF06213.12 CDJ46093.1 - 0.007 15.8 31.9 0.0092 15.4 31.9 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT DDHD PF02862.17 CDJ46093.1 - 0.0076 16.4 17.3 0.0097 16.1 17.3 1.3 1 0 0 1 1 1 1 DDHD domain BAF1_ABF1 PF04684.13 CDJ46093.1 - 0.0082 15.3 16.2 0.0087 15.2 16.2 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DUF4228 PF14009.6 CDJ46093.1 - 0.01 16.2 9.3 0.013 15.9 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) CDC45 PF02724.14 CDJ46093.1 - 0.013 13.9 16.8 0.013 13.9 16.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 CDJ46093.1 - 0.016 15.3 16.7 0.019 15.0 16.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 CDJ46093.1 - 0.018 13.8 18.6 0.019 13.8 18.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 CDJ46093.1 - 0.019 13.9 11.5 0.021 13.7 11.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SLC12 PF03522.15 CDJ46093.1 - 0.026 13.6 21.6 0.027 13.5 21.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S15 PF02129.18 CDJ46093.1 - 0.026 14.1 13.7 0.031 13.9 13.7 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BORG_CEP PF14957.6 CDJ46093.1 - 0.035 15.3 13.1 0.04 15.1 13.1 1.2 1 0 0 1 1 1 0 Cdc42 effector DUF966 PF06136.13 CDJ46093.1 - 0.039 13.7 14.0 0.039 13.7 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAPS PF04499.15 CDJ46093.1 - 0.05 12.4 14.2 0.053 12.3 14.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 CDJ46093.1 - 0.055 13.3 25.6 0.068 13.0 25.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.9 CDJ46093.1 - 0.067 13.3 18.8 0.081 13.0 18.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Hid1 PF12722.7 CDJ46093.1 - 0.072 11.2 20.0 0.07 11.3 20.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MCM_bind PF09739.9 CDJ46093.1 - 0.083 11.3 19.4 0.094 11.1 19.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor UPF0560 PF10577.9 CDJ46093.1 - 0.096 11.2 31.5 0.12 10.9 31.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Lin-8 PF03353.15 CDJ46093.1 - 0.1 12.2 26.5 0.11 12.1 26.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2828 PF11443.8 CDJ46093.1 - 0.11 10.6 21.1 0.13 10.3 21.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4045 PF13254.6 CDJ46093.1 - 0.11 12.1 22.3 0.12 12.0 22.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) AF-4 PF05110.13 CDJ46093.1 - 0.12 10.4 28.3 0.13 10.3 28.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF5427 PF10310.9 CDJ46093.1 - 0.14 11.1 26.5 0.17 10.8 26.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF913 PF06025.12 CDJ46093.1 - 0.16 11.0 15.3 0.18 10.7 15.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Band_3_cyto PF07565.13 CDJ46093.1 - 0.16 11.8 19.8 0.21 11.4 19.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GPCR_chapero_1 PF11904.8 CDJ46093.1 - 0.17 11.3 11.7 0.17 11.3 11.7 1.1 1 0 0 1 1 1 0 GPCR-chaperone Pannexin_like PF12534.8 CDJ46093.1 - 0.18 10.9 19.7 0.24 10.5 19.7 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Endostatin PF06482.11 CDJ46093.1 - 0.19 11.1 22.4 0.23 10.9 22.4 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin MIIP PF15734.5 CDJ46093.1 - 0.19 11.2 16.7 0.22 11.0 16.7 1.1 1 0 0 1 1 1 0 Migration and invasion-inhibitory GREB1 PF15782.5 CDJ46093.1 - 0.21 8.7 23.1 0.21 8.7 23.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glyco_transf_41 PF13844.6 CDJ46093.1 - 0.24 9.8 9.9 0.25 9.7 9.9 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 41 Velvet PF11754.8 CDJ46093.1 - 0.24 11.3 23.3 0.29 11.0 23.3 1.1 1 0 0 1 1 1 0 Velvet factor CCSAP PF15748.5 CDJ46093.1 - 0.24 11.5 28.5 0.26 11.4 28.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Hamartin PF04388.12 CDJ46093.1 - 0.25 10.0 19.7 0.26 9.9 19.7 1.0 1 0 0 1 1 1 0 Hamartin protein DUF1387 PF07139.11 CDJ46093.1 - 0.27 10.9 21.4 0.3 10.8 21.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) FAM60A PF15396.6 CDJ46093.1 - 0.27 11.2 19.5 0.34 10.9 19.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A NARP1 PF12569.8 CDJ46093.1 - 0.29 10.0 24.0 0.36 9.7 24.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PTPRCAP PF15713.5 CDJ46093.1 - 0.3 11.4 26.1 0.39 11.0 26.1 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated eIF-3_zeta PF05091.12 CDJ46093.1 - 0.32 9.9 32.0 0.41 9.6 32.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FancD2 PF14631.6 CDJ46093.1 - 0.32 8.3 12.8 0.36 8.2 12.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Plasmodium_Vir PF05795.11 CDJ46093.1 - 0.33 10.3 12.1 0.4 10.0 12.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Med24_N PF11277.8 CDJ46093.1 - 0.34 8.9 15.5 0.39 8.7 15.5 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF2126 PF09899.9 CDJ46093.1 - 0.36 8.9 16.6 0.42 8.6 16.6 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) MMR1 PF08505.10 CDJ46093.1 - 0.37 11.1 28.5 0.46 10.7 28.5 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Asp-B-Hydro_N PF05279.11 CDJ46093.1 - 0.41 10.7 17.2 0.44 10.6 17.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PA26 PF04636.13 CDJ46093.1 - 0.42 9.5 17.0 0.47 9.3 17.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Afi1 PF07792.12 CDJ46093.1 - 0.44 11.0 21.5 0.62 10.5 21.5 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Sec62 PF03839.16 CDJ46093.1 - 0.45 10.0 18.7 0.53 9.8 18.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SID-1_RNA_chan PF13965.6 CDJ46093.1 - 0.48 8.8 11.4 0.52 8.7 11.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Tim54 PF11711.8 CDJ46093.1 - 0.52 9.1 22.9 0.64 8.7 22.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Rtf2 PF04641.12 CDJ46093.1 - 0.54 9.6 21.5 0.68 9.3 21.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger NST1 PF13945.6 CDJ46093.1 - 0.56 10.3 31.9 0.77 9.8 31.9 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Activator_LAG-3 PF11498.8 CDJ46093.1 - 0.57 9.1 70.5 0.62 9.0 70.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Peptidase_S64 PF08192.11 CDJ46093.1 - 0.62 8.5 19.9 0.67 8.4 19.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.9 CDJ46093.1 - 0.62 8.3 44.7 0.64 8.2 44.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ALMT PF11744.8 CDJ46093.1 - 0.66 8.7 18.9 0.78 8.5 18.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Exonuc_VII_L PF02601.15 CDJ46093.1 - 0.66 9.5 22.6 0.66 9.5 22.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cellulose_synt PF03552.14 CDJ46093.1 - 0.68 8.4 10.3 0.76 8.2 10.3 1.0 1 0 0 1 1 1 0 Cellulose synthase Tho2 PF11262.8 CDJ46093.1 - 0.68 9.1 15.1 0.75 8.9 15.1 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Membralin PF09746.9 CDJ46093.1 - 0.71 8.9 14.4 0.79 8.7 14.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein PPP4R2 PF09184.11 CDJ46093.1 - 0.77 9.3 16.2 1 8.9 16.2 1.1 1 0 0 1 1 1 0 PPP4R2 SprA-related PF12118.8 CDJ46093.1 - 0.79 8.8 45.4 1 8.4 45.4 1.3 1 0 0 1 1 1 0 SprA-related family DUF2072 PF09845.9 CDJ46093.1 - 0.82 9.9 15.6 1.3 9.2 15.6 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein MDM10 PF12519.8 CDJ46093.1 - 0.84 8.4 19.9 0.93 8.3 19.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Pkinase_fungal PF17667.1 CDJ46093.1 - 0.84 8.3 11.3 0.86 8.3 11.3 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF4569 PF15133.6 CDJ46093.1 - 0.9 9.2 25.7 1.2 8.8 25.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Smg8_Smg9 PF10220.9 CDJ46093.1 - 0.99 7.6 22.6 1.1 7.4 22.6 1.0 1 0 0 1 1 1 0 Smg8_Smg9 DUF908 PF06012.12 CDJ46093.1 - 1 8.7 19.7 1.1 8.5 19.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TCP PF03634.13 CDJ46093.1 - 1 9.9 25.1 1.4 9.5 25.1 1.2 1 0 0 1 1 1 0 TCP family transcription factor Bul1_N PF04425.12 CDJ46093.1 - 1.1 7.9 18.3 1.3 7.7 18.3 1.1 1 0 0 1 1 1 0 Bul1 N terminus Ureide_permease PF07168.11 CDJ46093.1 - 1.1 7.9 9.5 1.5 7.5 9.5 1.4 1 0 0 1 1 1 0 Ureide permease Zip PF02535.22 CDJ46093.1 - 1.3 8.1 13.4 1.4 8.1 13.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SUFU_C PF12470.8 CDJ46093.1 - 1.9 8.5 15.0 2.7 8.0 15.0 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Paf1 PF03985.13 CDJ46093.1 - 2.1 7.3 30.3 2.7 6.9 30.3 1.1 1 0 0 1 1 1 0 Paf1 DUF4638 PF15472.6 CDJ46093.1 - 2.2 8.0 20.0 2.6 7.7 20.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Nop53 PF07767.11 CDJ46093.1 - 2.2 7.6 32.6 2.8 7.3 32.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Paramyxo_ncap PF00973.19 CDJ46093.1 - 2.3 7.1 18.9 2.3 7.0 18.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1682 PF07946.14 CDJ46093.1 - 2.5 7.2 22.1 3.1 6.9 22.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MAJIN PF15077.6 CDJ46093.1 - 2.6 7.8 18.2 3.3 7.4 18.2 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein VIR_N PF15912.5 CDJ46093.1 - 2.7 7.5 17.2 3.5 7.1 17.2 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal SelP_N PF04592.14 CDJ46093.1 - 3.2 7.1 23.8 4.5 6.6 23.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CAML PF14963.6 CDJ46093.1 - 4.1 7.4 8.1 4.6 7.3 8.1 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DHHW PF14286.6 CDJ46093.1 - 4.5 6.5 8.2 6.2 6.0 8.2 1.2 1 0 0 1 1 1 0 DHHW protein XRN_M PF17846.1 CDJ46093.1 - 4.9 6.0 18.2 6.1 5.7 18.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Dicty_REP PF05086.12 CDJ46093.1 - 5.7 4.8 16.5 6 4.7 16.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Scs3p PF10261.9 CDJ46093.1 - 6.1 6.3 8.1 8.8 5.7 8.1 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2370 PF10176.9 CDJ46093.1 - 6.4 6.3 14.4 8 6.0 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Kei1 PF08552.11 CDJ46093.1 - 6.5 6.6 18.1 9.1 6.1 18.1 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Connexin PF00029.19 CDJ46093.1 - 6.7 6.4 22.2 9.5 5.9 22.2 1.2 1 0 0 1 1 1 0 Connexin Med13_C PF06333.12 CDJ46093.1 - 7 5.8 18.8 8.1 5.6 18.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain eIF3_subunit PF08597.10 CDJ46093.1 - 7.4 6.4 29.1 12 5.7 29.1 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF3292 PF11696.8 CDJ46093.1 - 8 4.7 17.5 8.8 4.6 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) V_ATPase_I PF01496.19 CDJ46093.1 - 8.7 4.1 30.4 11 3.8 30.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DREPP PF05558.12 CDJ46093.1 - 9.3 6.1 9.0 11 5.8 9.0 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide PGI PF00342.19 CDJ46094.1 - 5.3e-23 81.4 0.0 6.8e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase BAF1_ABF1 PF04684.13 CDJ46096.1 - 4.6 6.2 22.4 5.9 5.8 22.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Red1 PF07964.11 CDJ46097.1 - 0.063 11.5 3.8 0.078 11.2 3.8 1.2 1 0 0 1 1 1 0 Rec10 / Red1 DUF572 PF04502.13 CDJ46097.1 - 2.7 7.5 13.9 3.3 7.2 13.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Myc_N PF01056.18 CDJ46097.1 - 9.7 6.0 20.4 0.74 9.7 8.1 2.0 1 1 1 2 2 2 0 Myc amino-terminal region SR-25 PF10500.9 CDJ46098.1 - 0.0039 16.9 4.9 0.0039 16.9 4.9 4.8 4 1 0 4 4 4 2 Nuclear RNA-splicing-associated protein MecA PF05389.12 CDJ46098.1 - 0.31 10.7 14.1 0.1 12.2 3.4 3.2 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) V_ATPase_I PF01496.19 CDJ46098.1 - 0.37 8.6 15.2 0.034 12.1 8.4 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Dpy19 PF10034.9 CDJ46098.1 - 0.38 8.9 1.2 0.54 8.4 0.1 1.7 2 0 0 2 2 2 0 Q-cell neuroblast polarisation eIF-3_zeta PF05091.12 CDJ46098.1 - 0.8 8.6 27.7 1.6 7.6 14.1 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) LMBR1 PF04791.16 CDJ46098.1 - 0.99 8.2 2.8 1.7 7.4 2.8 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein RR_TM4-6 PF06459.12 CDJ46099.1 - 0.02 14.7 22.2 0.025 14.4 22.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Endostatin PF06482.11 CDJ46099.1 - 0.048 13.1 17.9 0.058 12.8 17.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF913 PF06025.12 CDJ46099.1 - 0.14 11.1 11.9 0.15 11.0 11.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM60A PF15396.6 CDJ46099.1 - 0.14 12.2 12.9 0.16 11.9 12.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SID-1_RNA_chan PF13965.6 CDJ46099.1 - 0.18 10.2 5.2 0.2 10.0 5.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PPP4R2 PF09184.11 CDJ46099.1 - 0.22 11.0 11.1 0.24 10.9 11.1 1.1 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 CDJ46099.1 - 0.23 11.4 54.3 0.39 10.7 54.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 CDJ46099.1 - 0.31 9.3 19.5 0.36 9.1 19.5 1.1 1 0 0 1 1 1 0 CDC45-like protein VIR_N PF15912.5 CDJ46099.1 - 0.33 10.5 14.7 0.44 10.1 14.7 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal BORG_CEP PF14957.6 CDJ46099.1 - 0.34 12.1 13.5 0.46 11.7 13.5 1.3 1 0 0 1 1 1 0 Cdc42 effector SLC12 PF03522.15 CDJ46099.1 - 0.39 9.7 20.5 0.45 9.5 20.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CCDC71L PF15374.6 CDJ46099.1 - 0.42 9.8 20.7 0.52 9.5 20.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L STAC2_u1 PF16664.5 CDJ46099.1 - 0.52 10.8 13.4 0.72 10.3 13.4 1.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 ALMT PF11744.8 CDJ46099.1 - 0.52 9.1 13.5 0.6 8.9 13.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SAPS PF04499.15 CDJ46099.1 - 0.56 8.9 14.5 0.65 8.7 14.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TYW3 PF02676.14 CDJ46099.1 - 0.57 9.5 8.1 0.76 9.1 8.1 1.2 1 0 0 1 1 1 0 Methyltransferase TYW3 Asp-B-Hydro_N PF05279.11 CDJ46099.1 - 0.67 10.0 15.9 0.8 9.7 15.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region eIF-3_zeta PF05091.12 CDJ46099.1 - 0.72 8.8 25.6 1 8.3 25.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NPR3 PF03666.13 CDJ46099.1 - 0.77 8.5 19.9 0.96 8.2 19.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PA26 PF04636.13 CDJ46099.1 - 1.1 8.1 15.0 1.3 7.9 15.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SART-1 PF03343.13 CDJ46099.1 - 1.1 7.7 27.2 1.4 7.4 27.2 1.0 1 0 0 1 1 1 0 SART-1 family Tim54 PF11711.8 CDJ46099.1 - 1.1 7.9 21.1 1.6 7.4 21.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Paramyxo_ncap PF00973.19 CDJ46099.1 - 2.2 7.1 14.2 2.4 6.9 14.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Hid1 PF12722.7 CDJ46099.1 - 2.8 5.9 20.5 3.2 5.8 20.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lin-8 PF03353.15 CDJ46099.1 - 2.8 7.4 24.3 3.5 7.1 24.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Baculo_PP31 PF05311.11 CDJ46099.1 - 2.9 7.3 15.0 4.4 6.7 15.0 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Connexin PF00029.19 CDJ46099.1 - 3.3 7.4 16.0 4.9 6.8 16.0 1.3 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 CDJ46099.1 - 3.6 6.4 12.0 4.4 6.1 12.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SpoIIP PF07454.11 CDJ46099.1 - 4.2 6.8 24.0 6.2 6.2 24.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Peptidase_S15 PF02129.18 CDJ46099.1 - 4.4 6.8 17.1 6.5 6.3 17.1 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Band_3_cyto PF07565.13 CDJ46099.1 - 4.6 7.0 18.3 6.3 6.5 18.3 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MMR1 PF08505.10 CDJ46099.1 - 4.7 7.4 23.8 7.3 6.8 23.8 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4746 PF15928.5 CDJ46099.1 - 6 6.2 20.1 8.1 5.8 20.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4045 PF13254.6 CDJ46099.1 - 7.5 6.1 24.6 9.4 5.8 24.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF2828 PF11443.8 CDJ46099.1 - 8.9 4.3 21.8 12 3.8 21.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SprA-related PF12118.8 CDJ46099.1 - 9.5 5.2 46.1 13 4.8 46.1 1.2 1 0 0 1 1 1 0 SprA-related family Activator_LAG-3 PF11498.8 CDJ46101.1 - 0.2 10.6 15.9 0.22 10.5 15.9 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ46101.1 - 0.31 11.0 9.4 0.3 11.0 9.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ46101.1 - 0.43 10.2 13.5 0.47 10.0 13.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ46101.1 - 0.61 9.0 8.6 0.62 8.9 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2367 PF10164.9 CDJ46101.1 - 1.1 9.8 5.5 1.2 9.6 5.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) TERB2 PF15101.6 CDJ46102.1 - 0.015 15.3 8.5 0.015 15.3 8.5 5.6 4 2 1 5 5 5 0 Telomere-associated protein TERB2 RR_TM4-6 PF06459.12 CDJ46102.1 - 0.1 12.4 39.3 0.073 12.9 12.0 3.4 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 Macoilin PF09726.9 CDJ46103.1 - 0.33 9.4 32.2 0.49 8.9 32.2 1.2 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 CDJ46103.1 - 1.7 8.4 36.6 2.3 8.1 36.6 1.1 1 0 0 1 1 1 0 SPX domain TFIIF_alpha PF05793.12 CDJ46103.1 - 3 6.3 20.8 3.6 6.1 20.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Menin PF05053.13 CDJ46103.1 - 6.8 4.9 23.5 9.2 4.5 23.5 1.2 1 0 0 1 1 1 0 Menin Halogen_Hydrol PF10112.9 CDJ46104.1 - 0.003 17.6 0.3 0.0058 16.7 0.3 1.4 1 0 0 1 1 1 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2203 PF09969.9 CDJ46104.1 - 0.011 16.5 1.4 0.014 16.1 0.7 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2722 PF10846.8 CDJ46104.1 - 0.018 14.0 0.7 0.015 14.2 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Flavodoxin_2 PF02525.17 CDJ46104.1 - 0.02 14.6 0.9 0.032 13.9 0.9 1.4 1 1 0 1 1 1 0 Flavodoxin-like fold FliD_N PF02465.18 CDJ46104.1 - 0.14 12.8 5.8 0.075 13.7 3.9 1.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4400 PF14348.6 CDJ46104.1 - 0.22 11.0 4.4 0.39 10.2 4.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4400) TFIIA PF03153.13 CDJ46104.1 - 0.48 10.4 7.6 0.57 10.1 7.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC_tran_CTD PF16326.5 CDJ46104.1 - 0.73 10.1 8.9 0.83 10.0 6.2 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain Spt20 PF12090.8 CDJ46104.1 - 1.2 8.7 10.7 1.4 8.4 10.7 1.1 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ46104.1 - 3.2 6.5 9.6 3.8 6.3 9.6 1.1 1 0 0 1 1 1 0 Androgen receptor FAM176 PF14851.6 CDJ46105.1 - 1.4 8.6 9.1 1.6 8.4 5.7 2.2 2 0 0 2 2 2 0 FAM176 family Meleagrin PF08189.11 CDJ46105.1 - 1.5 8.6 6.8 12 5.6 2.3 2.4 2 0 0 2 2 2 0 Meleagrin/Cygnin family Borrelia_P83 PF05262.11 CDJ46105.1 - 2.2 6.7 12.7 2.7 6.4 12.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein NST1 PF13945.6 CDJ46105.1 - 6.2 6.9 26.1 18 5.4 25.0 2.1 1 1 1 2 2 2 0 Salt tolerance down-regulator eIF-3_zeta PF05091.12 CDJ46105.1 - 7.1 5.5 16.5 11 4.8 16.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RNB PF00773.19 CDJ46106.1 - 8.1e-16 58.2 5.1 1.2e-15 57.7 5.1 1.3 1 0 0 1 1 1 1 RNB domain SAGA-Tad1 PF12767.7 CDJ46106.1 - 0.0062 16.3 13.3 0.007 16.1 13.3 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Lin-8 PF03353.15 CDJ46106.1 - 0.0094 15.6 22.0 0.011 15.3 22.0 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 CDJ46106.1 - 0.015 13.6 44.7 0.018 13.3 44.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAPS PF04499.15 CDJ46106.1 - 0.042 12.7 17.5 0.047 12.5 17.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LAP1C PF05609.12 CDJ46106.1 - 0.077 12.1 26.3 0.1 11.7 26.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MRP-S31 PF15433.6 CDJ46106.1 - 0.085 12.5 28.9 0.11 12.2 28.9 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Pkinase_fungal PF17667.1 CDJ46106.1 - 0.089 11.6 7.2 0.11 11.2 7.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase GET2 PF08690.10 CDJ46106.1 - 0.37 10.4 30.1 0.52 9.9 30.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 SLC12 PF03522.15 CDJ46106.1 - 0.48 9.4 26.3 0.58 9.1 26.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 GAGA_bind PF06217.12 CDJ46106.1 - 0.6 10.3 25.9 0.74 10.0 25.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Draxin PF15550.6 CDJ46106.1 - 0.76 9.6 19.3 1.1 9.1 19.3 1.3 1 0 0 1 1 1 0 Draxin Hamartin PF04388.12 CDJ46106.1 - 0.82 8.3 23.4 1 7.9 23.4 1.1 1 0 0 1 1 1 0 Hamartin protein RR_TM4-6 PF06459.12 CDJ46106.1 - 1.4 8.7 31.6 2.2 8.1 31.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MAP7 PF05672.11 CDJ46106.1 - 1.7 8.3 52.3 3 7.5 52.3 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family CNDH2_C PF16858.5 CDJ46106.1 - 2.4 7.9 29.3 7.1 6.4 29.9 1.5 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Tic110 PF16940.5 CDJ46106.1 - 3.3 6.1 18.9 4.6 5.6 18.9 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter Membralin PF09746.9 CDJ46106.1 - 3.9 6.4 13.1 4.9 6.1 13.1 1.2 1 0 0 1 1 1 0 Tumour-associated protein VIR_N PF15912.5 CDJ46106.1 - 4.2 6.9 17.4 5.7 6.5 17.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Exonuc_VII_L PF02601.15 CDJ46106.1 - 5.2 6.5 31.6 6.8 6.2 31.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit O-antigen_lig PF13425.6 CDJ46106.1 - 5.9 5.6 7.6 7.2 5.3 7.6 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ALMT PF11744.8 CDJ46106.1 - 6.9 5.4 23.8 8.8 5.0 23.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CRT10 PF08728.10 CDJ46106.1 - 7.1 4.7 10.5 10 4.1 10.5 1.2 1 0 0 1 1 1 0 CRT10 Rrn6 PF10214.9 CDJ46106.1 - 8.1 4.8 30.8 10 4.5 30.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MSP1_C PF07462.11 CDJ46106.1 - 8.8 4.9 13.6 13 4.4 13.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Spt20 PF12090.8 CDJ46107.1 - 0.00037 20.2 12.2 0.00037 20.2 12.2 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ46107.1 - 0.00077 18.5 8.2 0.00077 18.5 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) NST1 PF13945.6 CDJ46107.1 - 0.011 15.8 7.1 0.013 15.7 7.1 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator CDRT4 PF15213.6 CDJ46107.1 - 0.11 13.1 2.7 0.13 12.8 2.7 1.1 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein SOG2 PF10428.9 CDJ46107.1 - 0.13 11.5 9.7 0.14 11.3 9.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 CDJ46107.1 - 0.13 12.2 18.1 0.15 12.0 18.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5427 PF10310.9 CDJ46107.1 - 0.38 9.7 14.9 0.42 9.5 14.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) TERB2 PF15101.6 CDJ46107.1 - 0.91 9.5 9.5 1 9.3 9.5 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 CDJ46107.1 - 0.95 8.2 7.7 1.1 8.0 7.7 1.1 1 0 0 1 1 1 0 Presenilin Roughex PF06020.11 CDJ46107.1 - 1.9 7.5 6.7 1.9 7.5 6.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein BRF1 PF07741.13 CDJ46107.1 - 2.5 8.5 10.2 3.6 8.0 10.2 1.3 1 1 0 1 1 1 0 Brf1-like TBP-binding domain UPF0560 PF10577.9 CDJ46107.1 - 2.8 6.3 10.9 3.2 6.2 10.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 eIF-3_zeta PF05091.12 CDJ46107.1 - 6.2 5.7 10.9 7.2 5.5 10.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ46107.1 - 9.4 6.2 6.3 10 6.1 6.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 CDJ46107.1 - 10 4.7 10.6 10 4.6 10.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RskA PF10099.9 CDJ46108.1 - 0.00034 21.0 6.5 0.00034 21.0 6.5 2.4 1 1 0 2 2 2 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ46108.1 - 0.18 12.4 18.5 0.24 12.0 17.0 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein SID-1_RNA_chan PF13965.6 CDJ46108.1 - 0.34 9.3 7.3 0.34 9.3 7.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GREB1 PF15782.5 CDJ46108.1 - 0.91 6.6 25.9 1.1 6.3 25.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 CDJ46108.1 - 1.3 8.8 37.9 0.52 10.1 27.9 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SelP_N PF04592.14 CDJ46108.1 - 2 7.8 43.9 0.28 10.6 40.1 1.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF2052 PF09747.9 CDJ46108.1 - 2.1 8.5 33.1 0.56 10.3 22.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PHD PF00628.29 CDJ46109.1 - 4.1e-05 23.4 5.9 0.00016 21.5 5.9 2.0 1 0 0 1 1 1 1 PHD-finger BUD22 PF09073.10 CDJ46109.1 - 0.00027 20.4 9.0 0.00027 20.4 9.0 6.0 4 3 2 6 6 6 2 BUD22 AT_hook PF02178.19 CDJ46109.1 - 1.1 9.4 7.6 4.4 7.5 7.6 2.1 1 0 0 1 1 1 0 AT hook motif Spt20 PF12090.8 CDJ46110.1 - 0.014 15.0 1.6 0.014 15.0 1.6 1.0 1 0 0 1 1 1 0 Spt20 family DUF3682 PF12446.8 CDJ46111.1 - 0.0036 17.8 22.1 0.0036 17.8 22.1 17.5 12 6 3 15 15 15 1 Protein of unknown function (DUF3682) RskA PF10099.9 CDJ46111.1 - 0.0047 17.2 24.1 0.0047 17.2 24.1 15.7 3 2 8 11 11 11 2 Anti-sigma-K factor rskA EOS1 PF12326.8 CDJ46111.1 - 0.52 10.2 0.0 0.52 10.2 0.0 4.1 5 1 0 5 5 5 0 N-glycosylation protein MCU PF04678.13 CDJ46111.1 - 1.2 9.2 8.0 1.8 8.6 1.5 2.9 2 0 0 2 2 2 0 Mitochondrial calcium uniporter FAM91_C PF14648.6 CDJ46111.1 - 4.6 6.0 10.8 1 8.1 0.1 2.4 2 0 0 2 2 2 0 FAM91 C-terminus CNDH2_C PF16858.5 CDJ46111.1 - 4.7 7.0 22.7 4 7.2 3.1 2.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term GNAT_acetyltr_2 PF13718.6 CDJ46111.1 - 4.9 6.5 8.9 1.8 7.9 0.8 2.7 2 0 0 2 2 2 0 GNAT acetyltransferase 2 SID-1_RNA_chan PF13965.6 CDJ46111.1 - 7.7 4.8 5.0 13 4.1 0.2 2.3 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Big_6 PF17936.1 CDJ46113.1 - 0.081 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial Ig domain RskA PF10099.9 CDJ46118.1 - 3.9e-06 27.3 0.0 3.9e-06 27.3 0.0 9.6 4 4 1 6 6 6 1 Anti-sigma-K factor rskA Apt1 PF10351.9 CDJ46119.1 - 0.17 10.7 10.4 0.2 10.5 10.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ46119.1 - 0.18 11.7 7.8 0.27 11.1 7.8 1.4 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 CDJ46119.1 - 1.7 8.2 37.1 0.78 9.3 5.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RIFIN PF02009.16 CDJ46119.1 - 1.8 8.4 6.9 2.3 8.0 6.9 1.2 1 0 0 1 1 1 0 Rifin Ribosomal_60s PF00428.19 CDJ46119.1 - 6.5 7.4 33.2 0.81 10.3 8.0 2.8 2 1 0 2 2 2 0 60s Acidic ribosomal protein Hexokinase_1 PF00349.21 CDJ46120.1 - 6.8e-35 120.8 0.0 8.4e-17 61.7 0.0 2.2 1 1 1 2 2 2 2 Hexokinase Hexokinase_2 PF03727.16 CDJ46120.1 - 6.4e-27 94.5 0.0 1e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 Hexokinase KdgT PF03812.13 CDJ46120.1 - 4.6 6.5 9.0 6.9 5.9 9.0 1.2 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease TFIIA PF03153.13 CDJ46121.1 - 2.4e-05 24.5 46.0 0.0007 19.7 11.0 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ46121.1 - 0.00016 21.8 23.4 0.00083 19.4 3.3 2.3 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) DUF5523 PF17661.1 CDJ46121.1 - 0.00039 20.2 20.2 0.015 15.0 6.6 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5523) RPA43_OB PF17875.1 CDJ46121.1 - 0.0012 19.4 10.5 0.072 13.7 2.2 2.5 2 0 0 2 2 2 2 RPA43 OB domain in RNA Pol I eIF-3_zeta PF05091.12 CDJ46121.1 - 0.0021 17.2 22.9 0.032 13.2 4.9 2.1 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CobT PF06213.12 CDJ46121.1 - 0.0027 17.1 33.3 0.068 12.5 12.2 3.1 3 0 0 3 3 3 2 Cobalamin biosynthesis protein CobT DUF1645 PF07816.11 CDJ46121.1 - 0.0039 17.8 17.2 0.0058 17.2 8.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1645) Connexin PF00029.19 CDJ46121.1 - 0.0052 16.6 12.8 0.12 12.1 3.6 2.3 2 0 0 2 2 2 2 Connexin OATP PF03137.20 CDJ46121.1 - 0.0093 14.3 11.4 0.07 11.4 0.6 2.2 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF2722 PF10846.8 CDJ46121.1 - 0.0097 14.9 50.8 0.064 12.2 15.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ46121.1 - 0.01 16.5 4.4 0.01 16.5 4.4 3.4 3 1 1 4 4 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAP1 PF08601.10 CDJ46121.1 - 0.014 15.2 16.1 0.056 13.2 15.8 1.9 1 1 1 2 2 2 0 Transcription factor PAP1 Serinc PF03348.15 CDJ46121.1 - 0.016 14.2 0.2 0.016 14.2 0.2 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF3464 PF11947.8 CDJ46121.1 - 0.016 14.9 18.5 0.65 9.7 4.1 3.0 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 CLN3 PF02487.17 CDJ46121.1 - 0.019 14.0 12.2 0.47 9.4 0.8 2.3 2 0 0 2 2 2 0 CLN3 protein FAM176 PF14851.6 CDJ46121.1 - 0.025 14.2 15.1 0.44 10.2 1.3 2.4 2 0 0 2 2 2 0 FAM176 family SpoIIP PF07454.11 CDJ46121.1 - 0.072 12.5 23.8 0.73 9.2 6.2 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) YABBY PF04690.13 CDJ46121.1 - 0.077 13.6 15.2 0.27 11.8 5.4 2.5 2 0 0 2 2 2 0 YABBY protein EIF4E-T PF10477.9 CDJ46121.1 - 0.12 11.2 34.1 0.15 10.8 34.1 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Tim54 PF11711.8 CDJ46121.1 - 0.14 11.0 17.5 0.39 9.4 2.5 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 CDJ46121.1 - 0.14 12.3 19.7 0.77 9.9 4.0 2.7 3 0 0 3 3 2 0 Cleavage and polyadenylation factor 2 C-terminal BORG_CEP PF14957.6 CDJ46121.1 - 0.16 13.1 18.9 1 10.5 8.9 2.8 3 0 0 3 3 2 0 Cdc42 effector AAA_23 PF13476.6 CDJ46121.1 - 0.17 12.3 29.6 0.48 10.9 12.9 2.4 2 0 0 2 2 2 0 AAA domain DUF775 PF05603.12 CDJ46121.1 - 0.18 11.3 23.7 0.94 9.0 3.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF775) XRN_N PF03159.18 CDJ46121.1 - 0.18 11.2 17.2 0.15 11.5 3.2 2.2 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus EPL1 PF10513.9 CDJ46121.1 - 0.19 12.1 27.0 0.1 13.0 5.5 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like D123 PF07065.14 CDJ46121.1 - 0.22 10.7 14.4 1 8.4 1.3 2.3 2 0 0 2 2 2 0 D123 DUF4484 PF14831.6 CDJ46121.1 - 0.25 11.4 17.2 0.62 10.1 1.3 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4484) Med15 PF09606.10 CDJ46121.1 - 0.34 9.5 48.9 0.67 8.6 17.8 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal NPR1_interact PF15699.5 CDJ46121.1 - 0.34 11.5 22.2 1.8 9.2 6.9 3.0 2 0 0 2 2 2 0 NPR1 interacting Lin-8 PF03353.15 CDJ46121.1 - 0.37 10.3 31.8 0.75 9.3 17.6 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF3391 PF11871.8 CDJ46121.1 - 0.4 11.2 20.4 1.7 9.2 3.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) FYDLN_acid PF09538.10 CDJ46121.1 - 0.46 11.2 14.3 0.68 10.6 0.6 2.7 3 0 0 3 3 2 0 Protein of unknown function (FYDLN_acid) HNOBA PF07701.14 CDJ46121.1 - 0.48 9.8 17.4 0.57 9.6 2.2 2.5 2 0 0 2 2 2 0 Heme NO binding associated DUF1980 PF09323.10 CDJ46121.1 - 0.55 10.1 16.6 0.22 11.4 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) EIIBC-GUT_N PF03612.14 CDJ46121.1 - 0.62 9.8 20.4 2.5 7.8 5.2 2.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus RPN2_C PF18004.1 CDJ46121.1 - 0.69 9.8 21.9 0.32 10.9 5.2 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3408 PF11888.8 CDJ46121.1 - 0.93 9.6 26.6 0.17 12.0 6.6 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF3408) GREB1 PF15782.5 CDJ46121.1 - 1.1 6.3 27.0 0.83 6.7 16.3 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Gti1_Pac2 PF09729.9 CDJ46121.1 - 1.2 9.2 19.6 1.2 9.2 1.5 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family DUF4175 PF13779.6 CDJ46121.1 - 1.3 6.8 49.7 1.2 6.9 16.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Paf1 PF03985.13 CDJ46121.1 - 1.3 7.9 26.5 1.4 7.8 10.1 2.3 2 0 0 2 2 2 0 Paf1 Peroxin-13_N PF04088.13 CDJ46121.1 - 1.4 9.2 23.2 0.15 12.3 1.5 4.0 4 1 0 4 4 3 0 Peroxin 13, N-terminal region DUF4518 PF15008.6 CDJ46121.1 - 1.5 8.0 22.4 2.1 7.5 7.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) Spore_coat_CotO PF14153.6 CDJ46121.1 - 1.6 8.7 32.9 3.5 7.5 12.3 2.4 2 0 0 2 2 2 0 Spore coat protein CotO DUF3276 PF11680.8 CDJ46121.1 - 1.6 8.9 18.1 2 8.6 4.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) GNAT_acetyltr_2 PF13718.6 CDJ46121.1 - 1.6 8.1 16.7 0.6 9.5 2.9 2.5 2 0 0 2 2 2 0 GNAT acetyltransferase 2 MDM31_MDM32 PF08118.11 CDJ46121.1 - 1.6 7.3 17.4 1.1 7.8 4.5 2.3 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins CCSAP PF15748.5 CDJ46121.1 - 1.9 8.6 29.1 4.6 7.3 14.4 2.5 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated NARP1 PF12569.8 CDJ46121.1 - 1.9 7.3 26.5 1 8.2 13.0 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 CDJ46121.1 - 1.9 8.2 25.9 3.1 7.5 7.8 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4770 PF15994.5 CDJ46121.1 - 2 8.6 31.3 0.44 10.8 6.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) Ureide_permease PF07168.11 CDJ46121.1 - 2.2 6.9 11.6 3.3 6.4 0.9 2.3 2 0 0 2 2 2 0 Ureide permease DUF2464 PF10240.9 CDJ46121.1 - 2.2 7.8 13.7 6.4 6.3 6.3 2.2 2 0 0 2 2 2 0 Multivesicular body subunit 12 HABP4_PAI-RBP1 PF04774.15 CDJ46121.1 - 2.2 9.1 22.5 1.4 9.8 5.2 2.7 3 0 0 3 3 2 0 Hyaluronan / mRNA binding family Mak16 PF04874.14 CDJ46121.1 - 2.5 8.8 18.8 10 6.8 5.2 3.5 3 0 0 3 3 3 0 Mak16 protein C-terminal region DUF1943 PF09172.11 CDJ46121.1 - 2.6 7.2 13.5 0.73 9.0 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) SLC12 PF03522.15 CDJ46121.1 - 2.7 6.9 25.1 0.53 9.3 3.2 2.1 2 0 0 2 2 2 0 Solute carrier family 12 LTV PF04180.14 CDJ46121.1 - 2.8 7.6 28.6 1.3 8.7 12.4 2.7 3 0 0 3 3 3 0 Low temperature viability protein RskA PF10099.9 CDJ46121.1 - 3.5 7.9 21.8 8.7 6.6 4.0 3.1 2 1 0 2 2 2 0 Anti-sigma-K factor rskA FAM76 PF16046.5 CDJ46121.1 - 3.6 6.9 25.7 2.8 7.2 4.6 2.4 2 0 0 2 2 2 0 FAM76 protein PSK PF06404.12 CDJ46121.1 - 3.7 8.6 22.9 6.8 7.8 6.7 3.1 3 0 0 3 3 2 0 Phytosulfokine precursor protein (PSK) Asp-B-Hydro_N PF05279.11 CDJ46121.1 - 3.9 7.5 17.2 3 7.9 3.2 2.5 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_60s PF00428.19 CDJ46121.1 - 4 8.1 17.2 0.31 11.7 2.0 3.1 3 1 0 3 3 2 0 60s Acidic ribosomal protein Nucleoside_tran PF01733.18 CDJ46121.1 - 4 6.7 7.6 4.6 6.5 0.5 2.4 2 0 0 2 2 2 0 Nucleoside transporter CSG2 PF16965.5 CDJ46121.1 - 4.7 6.0 11.8 2.8 6.8 0.6 2.3 2 0 0 2 2 2 0 Ceramide synthase regulator Androgen_recep PF02166.16 CDJ46121.1 - 5.4 5.8 57.0 0.076 11.9 20.8 3.0 3 0 0 3 3 3 0 Androgen receptor DUF4065 PF13274.6 CDJ46121.1 - 5.4 7.9 8.9 1.5 9.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) DUF3807 PF12720.7 CDJ46121.1 - 5.5 7.2 33.6 3.4 7.9 8.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) ATP11 PF06644.11 CDJ46121.1 - 6.8 6.4 29.7 5.2 6.8 9.6 2.9 3 0 0 3 3 3 0 ATP11 protein PTPRCAP PF15713.5 CDJ46121.1 - 6.9 6.9 27.4 9.1 6.6 11.0 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Saw1 PF11561.8 CDJ46121.1 - 7.1 6.1 15.8 1.3 8.5 3.3 2.3 2 0 0 2 2 2 0 Single strand annealing-weakened 1 CSRNP_N PF16019.5 CDJ46121.1 - 7.3 6.4 21.8 3 7.7 2.6 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus AbLIM_anchor PF16182.5 CDJ46121.1 - 7.7 6.2 21.5 3.3 7.5 2.0 2.4 2 0 0 2 2 2 0 Putative adherens-junction anchoring region of AbLIM MMR1 PF08505.10 CDJ46121.1 - 7.9 6.7 32.2 2.7 8.2 7.0 2.5 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein VIR_N PF15912.5 CDJ46121.1 - 8.5 5.9 13.8 6.8 6.2 2.6 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal Rxt3 PF08642.10 CDJ46121.1 - 8.7 7.1 19.3 2.5 8.9 2.0 2.6 2 1 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF4638 PF15472.6 CDJ46121.1 - 9.3 5.9 19.2 4.5 6.9 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) Peptidase_U57 PF05582.12 CDJ46121.1 - 9.5 5.4 17.9 1.9 7.7 5.6 2.3 2 0 0 2 2 2 0 YabG peptidase U57 Exo_endo_phos PF03372.23 CDJ46122.1 - 1.6e-14 54.0 0.0 1.9e-13 50.5 0.0 2.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RskA PF10099.9 CDJ46122.1 - 9e-11 42.4 11.0 2.5e-06 27.9 0.0 10.9 5 4 2 8 8 8 3 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ46122.1 - 0.00017 21.3 15.1 0.00017 21.3 15.1 9.5 7 2 2 9 9 9 3 Spt20 family DDHD PF02862.17 CDJ46122.1 - 0.0061 16.7 0.3 0.0061 16.7 0.3 7.8 3 1 1 5 5 5 2 DDHD domain Pex14_N PF04695.13 CDJ46122.1 - 0.011 16.4 8.6 0.011 16.4 8.6 12.2 5 3 5 10 10 10 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3671 PF12420.8 CDJ46122.1 - 3 8.0 6.2 6.2 6.9 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function MafB19-deam PF14437.6 CDJ46123.1 - 8.8e-06 25.5 0.8 1.6e-05 24.6 0.8 1.4 1 0 0 1 1 1 1 MafB19-like deaminase CytochromB561_N PF09786.9 CDJ46123.1 - 0.049 12.6 17.0 0.058 12.4 17.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal RskA PF10099.9 CDJ46123.1 - 0.29 11.4 23.7 0.51 10.6 0.0 2.8 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Apt1 PF10351.9 CDJ46123.1 - 1.8 7.3 16.6 2.1 7.1 16.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 CDJ46123.1 - 2.6 5.1 19.7 2.8 5.0 19.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Atrophin-1 PF03154.15 CDJ46124.1 - 0.36 9.0 4.1 0.45 8.7 4.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family CDP-OH_P_transf PF01066.21 CDJ46125.1 - 8.2e-08 32.9 2.6 2.9e-07 31.1 2.6 2.0 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase KH_1 PF00013.29 CDJ46126.1 - 4.2e-37 125.8 6.4 3.8e-12 45.9 1.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CDJ46126.1 - 2.3e-09 37.0 5.8 0.0072 16.1 0.9 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CDJ46126.1 - 2e-06 27.6 0.6 0.91 9.4 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CDJ46126.1 - 0.00014 21.9 7.6 0.56 10.3 0.0 3.3 3 0 0 3 3 3 3 NusA-like KH domain Spt20 PF12090.8 CDJ46126.1 - 2.1 7.9 21.2 2.3 7.8 8.6 2.2 2 0 0 2 2 2 0 Spt20 family MFS_2 PF13347.6 CDJ46127.1 - 3.1e-42 144.6 18.7 4.6e-39 134.2 10.7 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 CDJ46127.1 - 2.6e-07 29.9 29.1 6e-06 25.4 24.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DHHC PF01529.20 CDJ46127.1 - 0.93 9.6 3.2 1.4 9.0 2.3 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase Peptidase_M3 PF01432.20 CDJ46128.1 - 0.017 14.4 0.0 0.47 9.7 0.0 2.0 1 1 0 1 1 1 0 Peptidase family M3 COE1_HLH PF16423.5 CDJ46128.1 - 0.037 13.7 0.0 0.066 12.9 0.0 1.5 1 1 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain Ras PF00071.22 CDJ46129.1 - 2.9e-39 134.3 0.1 3.4e-39 134.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ46129.1 - 2e-19 69.9 0.1 4.7e-19 68.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ46129.1 - 2.2e-06 27.2 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ46129.1 - 2.2e-06 27.3 0.0 4.9e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RCC1 PF00415.18 CDJ46130.1 - 7.9e-08 32.8 1.5 0.0068 17.0 0.0 4.7 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat SR-25 PF10500.9 CDJ46130.1 - 5.2e-07 29.5 19.8 5.2e-07 29.5 19.8 6.3 5 1 1 6 6 5 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ46130.1 - 1.9e-06 28.3 0.0 1.9e-06 28.3 0.0 6.7 3 1 1 4 4 3 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ46130.1 - 0.00012 21.2 8.8 0.00012 21.2 8.8 7.1 3 2 3 6 6 2 2 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ46130.1 - 0.00034 19.7 12.0 0.00034 19.7 12.0 4.5 4 0 0 4 4 2 2 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ46130.1 - 0.00057 20.0 55.3 0.00057 20.0 55.3 4.2 1 1 3 4 4 3 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ46130.1 - 0.005 16.5 14.6 0.005 16.5 14.6 5.9 4 2 2 6 6 4 1 Spt20 family Cwf_Cwc_15 PF04889.12 CDJ46130.1 - 0.0066 16.2 6.8 0.0066 16.2 6.8 4.9 3 2 0 3 3 1 1 Cwf15/Cwc15 cell cycle control protein DUF3395 PF11875.8 CDJ46130.1 - 0.02 14.8 0.2 0.02 14.8 0.2 6.0 5 1 0 5 5 4 0 Domain of unknown function (DUF3395) FAP PF07174.11 CDJ46130.1 - 7.9 5.8 44.4 0.074 12.5 33.0 2.4 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Exonuc_VII_L PF02601.15 CDJ46130.1 - 9 5.8 46.6 0.0092 15.6 6.7 4.4 4 0 0 4 4 4 0 Exonuclease VII, large subunit AlaDh_PNT_C PF01262.21 CDJ46133.1 - 8.3e-29 100.4 1.4 2.1e-27 95.8 1.4 2.3 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 CDJ46133.1 - 2.3e-05 24.5 0.1 4.5e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CDJ46133.1 - 3e-05 23.5 0.1 3e-05 23.5 0.1 2.1 2 0 0 2 2 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CDJ46133.1 - 0.00024 21.0 0.0 0.00024 21.0 0.0 2.8 3 1 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 CDJ46133.1 - 0.0005 19.4 0.0 0.00087 18.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF779 PF05610.11 CDJ46133.1 - 0.0028 17.9 0.0 0.014 15.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF779) Methyltransf_25 PF13649.6 CDJ46133.1 - 0.011 16.5 0.5 0.033 14.9 0.0 2.2 2 0 0 2 2 1 0 Methyltransferase domain NAD_binding_7 PF13241.6 CDJ46133.1 - 0.016 15.6 0.6 0.04 14.4 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 CDJ46133.1 - 0.019 15.2 0.0 0.019 15.2 0.0 2.9 3 2 2 5 5 4 0 Saccharopine dehydrogenase NADP binding domain MTS PF05175.14 CDJ46133.1 - 0.032 13.8 0.1 0.083 12.4 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase small domain Thi4 PF01946.17 CDJ46133.1 - 0.042 13.1 0.2 0.069 12.4 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 CDJ46133.1 - 0.053 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.21 CDJ46133.1 - 0.068 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_11 PF08241.12 CDJ46133.1 - 0.081 13.6 0.4 0.41 11.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox_3 PF13738.6 CDJ46133.1 - 0.14 11.4 1.7 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_12 PF08242.12 CDJ46133.1 - 7.7 7.3 0.0 7.7 7.3 0.0 3.5 3 1 1 4 4 4 0 Methyltransferase domain AAA_23 PF13476.6 CDJ46133.1 - 8 6.9 12.9 10 6.6 11.8 1.7 2 0 0 2 2 2 0 AAA domain CLN3 PF02487.17 CDJ46133.1 - 8.6 5.3 12.2 0.98 8.4 1.7 2.4 2 0 0 2 2 2 0 CLN3 protein WD40 PF00400.32 CDJ46134.1 - 5.9e-10 39.6 1.1 0.0045 17.8 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ46134.1 - 2.1e-05 24.7 0.1 0.046 14.0 0.0 3.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RskA PF10099.9 CDJ46134.1 - 0.0012 19.2 17.4 0.0036 17.6 1.3 2.3 2 0 0 2 2 2 2 Anti-sigma-K factor rskA Nup160 PF11715.8 CDJ46134.1 - 0.0023 16.7 0.9 0.0047 15.6 0.1 1.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 SUIM_assoc PF16619.5 CDJ46134.1 - 0.39 10.8 7.8 0.083 13.0 3.3 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ46134.1 - 0.8 9.3 5.9 1.3 8.5 5.9 1.3 1 0 0 1 1 1 0 Spt20 family Adaptin_binding PF10199.9 CDJ46135.1 - 0.00092 19.8 2.0 0.00092 19.8 2.0 2.7 1 1 1 2 2 2 1 Alpha and gamma adaptin binding protein p34 RSB_motif PF16294.5 CDJ46135.1 - 0.0049 17.1 12.0 0.0049 17.1 12.0 3.1 4 0 0 4 4 4 1 RNSP1-SAP18 binding (RSB) motif GREB1 PF15782.5 CDJ46135.1 - 0.12 9.5 27.0 0.17 9.0 27.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CW_binding_2 PF04122.12 CDJ46135.1 - 0.5 11.1 3.3 7.5 7.3 0.8 2.9 3 0 0 3 3 3 0 Putative cell wall binding repeat 2 SLC12 PF03522.15 CDJ46135.1 - 1 8.3 31.7 2.1 7.3 31.7 1.5 1 0 0 1 1 1 0 Solute carrier family 12 DUF4637 PF15470.6 CDJ46135.1 - 3 7.6 19.1 0.34 10.6 1.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) TetR_C_24 PF17932.1 CDJ46135.1 - 4 7.7 10.0 0.27 11.5 3.7 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain N6_N4_Mtase PF01555.18 CDJ46135.1 - 4.9 6.8 7.8 25 4.5 7.8 1.9 1 1 0 1 1 1 0 DNA methylase Glyco_tran_WecB PF03808.13 CDJ46136.1 - 0.018 15.0 1.0 0.028 14.4 1.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DUF2431 PF10354.9 CDJ46136.1 - 0.037 14.3 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) SR-25 PF10500.9 CDJ46136.1 - 1.5 8.4 20.6 2.4 7.7 20.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAP2 PF01569.21 CDJ46137.1 - 8.5 6.1 15.8 0.78 9.5 6.8 2.7 1 1 0 2 2 2 0 PAP2 superfamily DUF755 PF05501.11 CDJ46138.1 - 1.5 9.1 28.8 2.8 8.2 6.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Lin-8 PF03353.15 CDJ46141.1 - 0.0018 17.9 17.8 0.0018 17.9 17.8 2.9 2 1 0 2 2 1 1 Ras-mediated vulval-induction antagonist PA26 PF04636.13 CDJ46141.1 - 0.056 12.4 36.4 0.27 10.1 9.7 2.3 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) SLC12 PF03522.15 CDJ46141.1 - 0.43 9.6 55.1 0.48 9.4 28.1 2.3 2 0 0 2 2 2 0 Solute carrier family 12 CENP-N PF05238.13 CDJ46141.1 - 0.43 9.8 33.7 0.023 14.0 7.1 2.2 2 0 0 2 2 2 0 Kinetochore protein CHL4 like Utp14 PF04615.13 CDJ46141.1 - 0.93 8.0 56.5 0.32 9.5 10.5 2.1 2 0 0 2 2 2 0 Utp14 protein CCDC84 PF14968.6 CDJ46141.1 - 1.7 8.2 48.2 2.2 7.8 12.7 2.2 2 0 0 2 2 2 0 Coiled coil protein 84 GREB1 PF15782.5 CDJ46141.1 - 2.3 5.2 70.4 0.021 12.0 40.9 2.3 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 CDJ46141.1 - 3.1 6.0 49.0 0.035 12.4 7.3 2.1 2 0 0 2 2 2 0 CDC45-like protein Peptidase_S64 PF08192.11 CDJ46141.1 - 6 5.2 58.5 0.13 10.7 13.5 2.3 2 0 0 2 2 2 0 Peptidase family S64 Cwf_Cwc_15 PF04889.12 CDJ46141.1 - 6 6.5 55.6 2.2 8.0 29.2 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Raftlin PF15250.6 CDJ46141.1 - 9.2 4.9 44.8 2.2 6.9 22.5 2.3 2 0 0 2 2 2 0 Raftlin Spt20 PF12090.8 CDJ46142.1 - 1.2 8.7 29.5 1.2 8.7 29.5 1.0 1 0 0 1 1 1 0 Spt20 family Conotoxin PF02950.17 CDJ46142.1 - 3.9 8.6 5.7 3.8 8.6 5.7 1.1 1 0 0 1 1 1 0 Conotoxin FAM176 PF14851.6 CDJ46142.1 - 5.5 6.6 7.2 5.4 6.7 7.2 1.0 1 0 0 1 1 1 0 FAM176 family ANAPC_CDC26 PF10471.9 CDJ46142.1 - 5.5 7.9 23.2 7 7.6 23.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 DUF4820 PF16091.5 CDJ46142.1 - 7.2 5.9 9.5 7 5.9 9.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Activator_LAG-3 PF11498.8 CDJ46144.1 - 0.0067 15.5 27.9 0.007 15.4 27.9 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 DUF2175 PF09943.9 CDJ46144.1 - 0.12 12.7 1.4 0.2 12.0 1.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Dehydrin PF00257.19 CDJ46144.1 - 0.28 11.7 3.8 0.43 11.1 3.8 1.3 1 0 0 1 1 1 0 Dehydrin TFIIA PF03153.13 CDJ46144.1 - 0.63 10.0 14.2 0.68 9.9 14.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ46144.1 - 2.4 7.7 15.3 2.8 7.4 15.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Noc2 PF03715.13 CDJ46146.1 - 6.3e-19 68.3 0.2 1.9e-18 66.8 0.2 1.8 1 0 0 1 1 1 1 Noc2p family SPX PF03105.19 CDJ46146.1 - 0.011 15.7 0.3 0.011 15.7 0.3 4.9 3 1 0 3 3 3 0 SPX domain KH_1 PF00013.29 CDJ46147.1 - 1.3e-29 101.8 0.0 3.9e-09 36.2 0.1 4.9 4 1 0 4 4 4 3 KH domain KH_2 PF07650.17 CDJ46147.1 - 7.1e-08 32.2 0.1 0.19 11.6 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CDJ46147.1 - 1.8e-05 24.7 0.6 0.067 13.3 0.1 3.3 3 0 0 3 3 3 1 NusA-like KH domain SR-25 PF10500.9 CDJ46147.1 - 1.6 8.3 9.5 2.5 7.7 9.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RPA43_OB PF17875.1 CDJ46150.1 - 0.013 16.1 0.2 0.013 16.1 0.2 6.2 5 1 0 5 5 5 0 RPA43 OB domain in RNA Pol I Methyltransf_15 PF09445.10 CDJ46152.1 - 9.4e-05 22.0 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase AviRa PF11599.8 CDJ46152.1 - 0.12 11.9 0.7 0.17 11.3 0.7 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa TFIIA PF03153.13 CDJ46152.1 - 0.82 9.6 7.4 1.5 8.8 7.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ46153.1 - 0.011 15.3 14.6 0.011 15.3 14.6 2.2 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein TSP9 PF11493.8 CDJ46153.1 - 0.083 13.6 8.3 3.4 8.4 2.7 2.5 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 DUF812 PF05667.11 CDJ46153.1 - 0.088 11.7 16.6 0.11 11.4 16.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF966 PF06136.13 CDJ46153.1 - 0.3 10.8 14.4 0.37 10.5 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peptidase_S15 PF02129.18 CDJ46153.1 - 0.79 9.3 14.7 0.31 10.6 9.3 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) RXLR PF16810.5 CDJ46153.1 - 1.7 9.0 9.6 0.84 10.1 3.0 2.2 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Sin_N PF04801.13 CDJ46153.1 - 2 7.6 23.5 2.7 7.1 23.5 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Med15 PF09606.10 CDJ46153.1 - 3.1 6.4 41.2 3.8 6.1 41.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MAT1 PF06391.13 CDJ46153.1 - 4.6 7.0 17.9 0.86 9.4 9.8 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 SDA1 PF05285.12 CDJ46154.1 - 0.0021 17.5 22.4 0.0025 17.3 22.4 1.2 1 0 0 1 1 1 1 SDA1 LAP1C PF05609.12 CDJ46154.1 - 0.15 11.1 11.6 0.24 10.5 11.6 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TAF4 PF05236.14 CDJ46154.1 - 1 9.0 20.6 4.4 7.0 20.6 1.8 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SLC12 PF03522.15 CDJ46154.1 - 1.1 8.2 11.0 1.7 7.6 11.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Apt1 PF10351.9 CDJ46154.1 - 1.1 8.0 10.3 1.3 7.8 10.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAPS PF04499.15 CDJ46154.1 - 1.6 7.4 12.7 2 7.1 12.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Arm PF00514.23 CDJ46155.1 - 2.3e-41 138.6 7.2 1e-13 50.8 0.0 5.5 5 1 1 6 6 6 4 Armadillo/beta-catenin-like repeat IBB PF01749.20 CDJ46155.1 - 3.3e-14 53.1 0.1 5.8e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 CDJ46155.1 - 7.7e-07 29.5 9.3 0.0011 19.4 0.0 4.6 4 1 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 CDJ46155.1 - 1.4e-06 28.6 0.8 0.00012 22.4 0.0 3.4 1 1 2 3 3 3 1 HEAT repeats HEAT PF02985.22 CDJ46155.1 - 9.8e-05 22.3 0.8 0.02 15.1 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat HEAT_PBS PF03130.16 CDJ46155.1 - 0.0052 17.3 2.4 0.8 10.6 0.3 4.2 3 1 0 3 3 3 1 PBS lyase HEAT-like repeat DUF3138 PF11336.8 CDJ46155.1 - 0.14 10.8 2.8 0.18 10.4 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Asp_protease_2 PF13650.6 CDJ46156.1 - 3.7e-06 27.5 0.1 1.7e-05 25.3 0.0 2.0 2 1 1 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ46156.1 - 7.7e-06 26.4 0.0 2.7e-05 24.6 0.0 1.9 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ46156.1 - 0.0011 18.8 0.0 0.0086 15.8 0.0 2.0 1 1 0 2 2 2 1 Retroviral aspartyl protease RVP PF00077.20 CDJ46156.1 - 0.0041 17.4 0.1 0.013 15.8 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ46156.1 - 0.073 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease Trp_leader2 PF08056.11 CDJ46156.1 - 0.077 13.0 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Tryptophan operon leader peptide rve PF00665.26 CDJ46158.1 - 2.9e-10 40.4 0.0 4.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ46158.1 - 1.7e-08 34.2 0.1 4e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF5427 PF10310.9 CDJ46159.1 - 0.74 8.7 31.3 0.81 8.6 31.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4746 PF15928.5 CDJ46159.1 - 3.2 7.1 19.8 3.7 6.9 19.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SUIM_assoc PF16619.5 CDJ46161.1 - 0.0049 16.9 21.0 0.12 12.4 3.2 2.7 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ46161.1 - 0.1 11.5 9.9 0.58 9.0 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) BRF1 PF07741.13 CDJ46161.1 - 0.14 12.5 6.5 0.18 12.2 0.9 2.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Draxin PF15550.6 CDJ46161.1 - 1.7 8.4 7.3 3.6 7.4 1.2 2.4 2 0 0 2 2 2 0 Draxin Spt20 PF12090.8 CDJ46161.1 - 4.3 6.9 21.2 2.2 7.8 8.6 2.2 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ46161.1 - 6 6.7 17.8 1.6 8.6 3.9 2.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ46164.1 - 0.00022 19.9 20.5 0.00022 19.9 20.5 4.5 4 1 0 4 4 4 2 Macoilin family GPI2 PF06432.11 CDJ46165.1 - 1.1e-21 77.6 0.5 2.2e-21 76.6 0.5 1.5 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase BBS2_C PF14782.6 CDJ46165.1 - 0.051 12.3 2.7 0.071 11.9 2.7 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal CDK2AP PF09806.9 CDJ46165.1 - 0.89 9.6 16.4 1.6 8.7 14.9 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein BAF1_ABF1 PF04684.13 CDJ46165.1 - 1.2 8.1 7.3 1.5 7.8 7.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.9 CDJ46165.1 - 8.4 4.5 14.7 10 4.2 14.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0016 PF01169.19 CDJ46166.1 - 1.2e-26 92.8 30.1 1.4e-16 60.6 4.5 3.3 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 Eapp_C PF10238.9 CDJ46166.1 - 0.066 13.3 0.3 0.066 13.3 0.3 2.6 3 0 0 3 3 3 0 E2F-associated phosphoprotein OATP PF03137.20 CDJ46166.1 - 0.14 10.4 0.1 0.75 8.0 0.1 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.13 CDJ46166.1 - 0.14 12.1 31.7 0.015 15.3 23.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ46166.1 - 0.24 11.2 0.6 0.5 10.1 0.6 1.5 1 0 0 1 1 1 0 Connexin Pap_E4 PF02711.14 CDJ46166.1 - 0.41 11.6 15.1 5.5 8.0 5.9 3.5 3 0 0 3 3 3 0 E4 protein eIF-3_zeta PF05091.12 CDJ46166.1 - 0.66 8.9 7.3 0.99 8.3 7.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SOG2 PF10428.9 CDJ46166.1 - 0.86 8.7 29.9 1.6 7.8 3.6 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein PAT1 PF09770.9 CDJ46166.1 - 7.3 4.7 24.0 11 4.2 24.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM176 PF14851.6 CDJ46166.1 - 8.8 6.0 10.0 4 7.1 3.6 2.8 3 0 0 3 3 3 0 FAM176 family Tim54 PF11711.8 CDJ46166.1 - 9.4 4.9 13.1 1.3 7.8 5.8 2.6 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 SR-25 PF10500.9 CDJ46167.1 - 0.0001 22.0 33.3 0.0001 22.0 33.3 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein PAT1 PF09770.9 CDJ46167.1 - 0.0052 15.1 34.3 0.0056 15.0 34.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SOBP PF15279.6 CDJ46167.1 - 0.0052 17.4 21.3 0.0057 17.3 21.3 1.2 1 0 0 1 1 1 1 Sine oculis-binding protein CDC27 PF09507.10 CDJ46167.1 - 0.016 14.6 27.2 0.021 14.3 27.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PI3K_1B_p101 PF10486.9 CDJ46167.1 - 0.033 12.0 15.6 0.041 11.7 15.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CAC1F_C PF16885.5 CDJ46167.1 - 0.09 12.4 19.5 0.11 12.2 19.5 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term PPP4R2 PF09184.11 CDJ46167.1 - 0.092 12.3 14.1 0.11 12.0 14.1 1.3 1 0 0 1 1 1 0 PPP4R2 DUF572 PF04502.13 CDJ46167.1 - 0.095 12.3 24.9 0.12 12.0 24.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Exonuc_VII_L PF02601.15 CDJ46167.1 - 0.12 11.9 25.2 0.14 11.7 25.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SLC12 PF03522.15 CDJ46167.1 - 0.16 11.0 22.3 0.2 10.7 22.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 MRP-S31 PF15433.6 CDJ46167.1 - 0.19 11.3 21.1 0.23 11.1 21.1 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 CDC45 PF02724.14 CDJ46167.1 - 0.21 9.8 20.0 0.26 9.5 20.0 1.3 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 CDJ46167.1 - 0.26 8.4 31.6 0.31 8.1 31.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 CDJ46167.1 - 0.3 10.3 19.4 0.44 9.7 19.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1387 PF07139.11 CDJ46167.1 - 0.4 10.4 26.7 0.63 9.7 26.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Ndc1_Nup PF09531.10 CDJ46167.1 - 0.43 9.2 27.4 0.49 9.0 27.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nuc_deoxyri_tr2 PF15891.5 CDJ46167.1 - 0.52 10.6 7.6 3 8.2 7.6 2.2 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like LAP1C PF05609.12 CDJ46167.1 - 0.55 9.3 31.2 0.7 8.9 31.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Endostatin PF06482.11 CDJ46167.1 - 0.61 9.5 22.1 0.9 8.9 22.1 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Pox_E2-like PF04497.12 CDJ46167.1 - 0.62 8.4 5.0 0.77 8.1 5.0 1.0 1 0 0 1 1 1 0 Poxviridae protein Menin PF05053.13 CDJ46167.1 - 0.8 8.0 21.3 1.1 7.6 21.3 1.1 1 0 0 1 1 1 0 Menin ABC2_membrane_3 PF12698.7 CDJ46167.1 - 0.87 8.6 5.2 1.1 8.3 5.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein MAP70 PF07058.11 CDJ46167.1 - 1.1 7.9 20.9 1.6 7.4 20.9 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 Hamartin PF04388.12 CDJ46167.1 - 1.1 7.8 26.7 1.4 7.5 26.7 1.0 1 0 0 1 1 1 0 Hamartin protein RIFIN PF02009.16 CDJ46167.1 - 1.2 9.0 21.2 1.6 8.6 21.2 1.1 1 0 0 1 1 1 0 Rifin RAP1 PF07218.11 CDJ46167.1 - 1.7 6.9 12.8 1.9 6.7 12.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF5523 PF17661.1 CDJ46167.1 - 2.1 8.0 20.7 2.7 7.6 20.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Radical_SAM_N PF08497.10 CDJ46167.1 - 3.7 6.7 12.6 4.8 6.3 12.6 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal CDK5_activator PF03261.15 CDJ46167.1 - 4 6.9 21.1 5 6.6 21.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4366 PF14283.6 CDJ46167.1 - 4.1 7.4 19.1 1.9 8.5 5.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) DUF5427 PF10310.9 CDJ46167.1 - 4.8 6.0 31.0 9.4 5.1 31.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PA26 PF04636.13 CDJ46167.1 - 5.2 5.9 18.0 6.8 5.5 18.0 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PARM PF17061.5 CDJ46167.1 - 6.8 6.7 24.6 9.6 6.3 24.6 1.1 1 0 0 1 1 1 0 PARM eIF-3_zeta PF05091.12 CDJ46167.1 - 8.4 5.2 26.4 12 4.7 26.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UCH PF00443.29 CDJ46168.1 - 4.9e-13 49.2 0.5 4.9e-13 49.2 0.5 8.7 6 3 1 7 7 7 1 Ubiquitin carboxyl-terminal hydrolase SMYLE_N PF18615.1 CDJ46169.1 - 0.48 9.9 31.7 0.98 8.9 31.7 1.5 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain FA_desaturase PF00487.24 CDJ46169.1 - 0.63 9.8 4.4 9.7 5.9 0.6 2.3 2 0 0 2 2 2 0 Fatty acid desaturase DUF966 PF06136.13 CDJ46169.1 - 4.5 6.9 33.3 7.1 6.2 33.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LAP1C PF05609.12 CDJ46169.1 - 5.7 5.9 36.6 9.3 5.2 36.6 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SR-25 PF10500.9 CDJ46170.1 - 1.4e-05 24.8 23.3 4.7e-05 23.1 14.1 2.0 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF572 PF04502.13 CDJ46170.1 - 1.1 8.9 26.1 1.6 8.2 26.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S49_N PF08496.10 CDJ46170.1 - 1.5 8.9 20.3 0.44 10.6 3.7 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal eIF3_subunit PF08597.10 CDJ46170.1 - 2.5 7.9 21.7 0.67 9.8 4.3 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit TCP PF03634.13 CDJ46170.1 - 4.2 7.9 32.2 0.56 10.8 14.9 2.1 2 0 0 2 2 2 0 TCP family transcription factor Asparaginase_2 PF01112.18 CDJ46170.1 - 9.3 5.2 17.2 4.3 6.3 4.8 2.1 2 0 0 2 2 2 0 Asparaginase CD20 PF04103.15 CDJ46171.1 - 0.0083 16.2 0.1 0.0083 16.2 0.1 3.5 1 1 1 2 2 2 1 CD20-like family Afi1 PF07792.12 CDJ46172.1 - 0.014 15.9 0.9 0.014 15.9 0.9 10.6 2 2 2 5 5 5 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2722 PF10846.8 CDJ46174.1 - 0.006 15.6 1.9 0.006 15.6 1.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Mrpl_C PF18502.1 CDJ46174.1 - 0.012 15.9 6.1 0.012 15.9 6.1 2.6 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain OmpH PF03938.14 CDJ46174.1 - 0.013 15.8 14.6 0.013 15.8 14.6 3.2 3 1 0 3 3 2 0 Outer membrane protein (OmpH-like) MAD PF05557.13 CDJ46174.1 - 0.018 13.4 25.0 0.028 12.8 6.9 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein Goodbye PF17109.5 CDJ46174.1 - 0.024 15.1 2.1 0.024 15.1 2.1 2.6 1 1 2 3 3 2 0 fungal STAND N-terminal Goodbye domain Tropomyosin PF00261.20 CDJ46174.1 - 0.031 13.6 23.6 0.09 12.1 7.8 2.2 2 0 0 2 2 2 0 Tropomyosin Spc7 PF08317.11 CDJ46174.1 - 0.11 11.3 28.0 0.16 10.8 11.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein FliD_C PF07195.12 CDJ46174.1 - 0.19 11.1 14.2 0.49 9.8 2.1 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus CENP-F_leu_zip PF10473.9 CDJ46174.1 - 0.56 10.2 33.0 0.29 11.1 15.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TFIIA PF03153.13 CDJ46174.1 - 1 9.3 25.5 1.5 8.7 25.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF724 PF05266.14 CDJ46174.1 - 1.5 8.6 16.7 0.55 10.0 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) HIP1_clath_bdg PF16515.5 CDJ46174.1 - 2.4 8.8 30.7 1.8 9.2 12.3 2.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LMBR1 PF04791.16 CDJ46174.1 - 2.5 6.9 6.9 3.3 6.5 6.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Leu_zip PF15294.6 CDJ46174.1 - 3.9 6.9 23.3 1.7 8.1 6.7 2.1 2 0 0 2 2 2 0 Leucine zipper GrpE PF01025.19 CDJ46174.1 - 4.5 6.9 19.6 3.4 7.3 4.4 2.5 2 0 0 2 2 2 0 GrpE Atg14 PF10186.9 CDJ46174.1 - 4.8 6.2 27.7 2.1 7.4 10.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF641 PF04859.12 CDJ46174.1 - 4.8 7.5 20.7 1.5 9.2 7.0 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) MCU PF04678.13 CDJ46174.1 - 5.3 7.1 17.5 2 8.5 4.8 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF2203 PF09969.9 CDJ46174.1 - 7.4 7.3 20.8 0.15 12.7 4.9 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 CDJ46174.1 - 8.5 6.9 34.4 8.1 7.0 13.6 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF2232 PF09991.9 CDJ46174.1 - 9 5.4 5.4 2.9 7.0 2.2 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) Mod_r PF07200.13 CDJ46174.1 - 9.2 6.4 32.3 0.71 10.0 9.7 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CENP-H PF05837.12 CDJ46174.1 - 9.4 6.7 25.4 4.9 7.6 11.2 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Spt20 PF12090.8 CDJ46175.1 - 0.0094 15.6 15.5 0.011 15.4 15.5 1.1 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ46175.1 - 0.19 11.7 19.2 0.23 11.4 19.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RLL PF10036.9 CDJ46175.1 - 3.2 7.5 13.5 3.6 7.4 13.5 1.0 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Miga PF10265.9 CDJ46175.1 - 4.4 6.2 10.5 4.5 6.1 10.5 1.0 1 0 0 1 1 1 0 Mitoguardin RIFIN PF02009.16 CDJ46175.1 - 8.6 6.1 12.9 12 5.7 12.9 1.2 1 0 0 1 1 1 0 Rifin Neur_chan_memb PF02932.16 CDJ46175.1 - 9.3 6.2 7.3 9.8 6.2 7.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 CDJ46176.1 - 0.0021 17.7 21.2 0.0021 17.7 21.2 3.6 2 1 1 3 3 3 1 Spt20 family MlaA PF04333.13 CDJ46176.1 - 0.044 13.5 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 MlaA lipoprotein SR-25 PF10500.9 CDJ46176.1 - 0.081 12.5 27.4 0.19 11.3 10.4 3.6 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein XPG_N PF00752.17 CDJ46177.1 - 4.7e-08 33.4 0.0 4.7e-08 33.4 0.0 2.5 3 0 0 3 3 1 1 XPG N-terminal domain MKT1_N PF12247.8 CDJ46177.1 - 1.7e-05 25.1 0.0 7.2e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication Connexin PF00029.19 CDJ46177.1 - 0.0092 15.8 19.2 0.18 11.6 1.5 2.5 2 0 0 2 2 2 2 Connexin DUF5523 PF17661.1 CDJ46177.1 - 0.24 11.1 33.3 0.98 9.1 5.6 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5523) SpoIIP PF07454.11 CDJ46177.1 - 0.37 10.2 32.0 0.66 9.4 4.1 3.0 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) MecA PF05389.12 CDJ46177.1 - 0.48 10.0 21.2 0.45 10.1 1.8 2.6 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) PBP1_TM PF14812.6 CDJ46177.1 - 0.55 10.6 18.8 0.24 11.8 10.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAT1 PF09770.9 CDJ46177.1 - 1.2 7.3 49.3 1.6 6.9 19.0 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RNA_pol_Rpc4 PF05132.14 CDJ46177.1 - 1.4 9.3 37.7 5 7.5 11.6 4.2 4 0 0 4 4 4 0 RNA polymerase III RPC4 Vfa1 PF08432.10 CDJ46177.1 - 3.6 7.9 32.0 1.1 9.6 1.3 3.0 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 DUF2052 PF09747.9 CDJ46177.1 - 4.8 7.3 34.3 1 9.4 18.0 2.8 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Folate_carrier PF01770.18 CDJ46177.1 - 5.6 5.6 15.2 3.4 6.3 2.4 2.4 2 0 0 2 2 2 0 Reduced folate carrier Isy1 PF06246.12 CDJ46177.1 - 6.7 6.2 27.6 3.6 7.1 3.5 2.5 2 0 0 2 2 2 0 Isy1-like splicing family K_channel_TID PF07941.11 CDJ46178.1 - 0.00046 20.6 4.3 0.00046 20.6 4.3 15.3 13 4 1 14 14 14 1 Potassium channel Kv1.4 tandem inactivation domain SUIM_assoc PF16619.5 CDJ46178.1 - 0.0043 17.1 0.1 0.0043 17.1 0.1 22.4 12 5 3 16 16 16 3 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ46179.1 - 0.00061 19.5 12.7 0.00061 19.5 12.7 11.9 7 2 3 11 11 11 1 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.8 CDJ46179.1 - 0.0029 16.7 7.0 0.0029 16.7 7.0 9.9 8 2 1 9 9 9 2 Transcriptional activator LAG-3 SH3_2 PF07653.17 CDJ46179.1 - 0.046 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DUF4366 PF14283.6 CDJ46180.1 - 0.0071 16.4 1.4 0.43 10.6 0.5 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) Zip PF02535.22 CDJ46180.1 - 0.2 10.9 1.7 4.1 6.5 0.2 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Peroxin-13_N PF04088.13 CDJ46180.1 - 4.2 7.6 6.7 7.6 6.8 0.5 3.1 3 0 0 3 3 3 0 Peroxin 13, N-terminal region Orf78 PF06024.12 CDJ46180.1 - 9.3 6.6 8.3 1.2 9.5 0.6 3.0 3 0 0 3 3 3 0 Orf78 (ac78) DUF3385 PF11865.8 CDJ46181.1 - 5.1 7.0 9.0 13 5.7 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Hydin_ADK PF17213.3 CDJ46182.1 - 0.11 12.8 11.8 0.14 12.4 11.8 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF5523 PF17661.1 CDJ46182.1 - 0.28 10.8 19.7 0.34 10.6 19.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Suf PF05843.14 CDJ46182.1 - 0.56 10.2 17.2 0.66 9.9 17.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ46182.1 - 3.1 7.7 32.1 4.4 7.2 32.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ46182.1 - 4.8 5.3 21.8 4.6 5.4 21.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.6 CDJ46182.1 - 5.7 6.2 22.0 7.1 5.9 22.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDJ46182.1 - 6.6 5.4 18.2 8.1 5.1 18.2 1.1 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ46182.1 - 8.5 3.3 13.1 9.4 3.2 13.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EphA2_TM PF14575.6 CDJ46183.1 - 1.7 9.6 0.0 1.7 9.6 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain ISAV_HA PF06215.11 CDJ46184.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin Leu_zip PF15294.6 CDJ46184.1 - 0.69 9.4 10.6 0.06 12.8 5.8 1.6 2 0 0 2 2 2 0 Leucine zipper DUF4834 PF16118.5 CDJ46184.1 - 7.8 7.5 15.0 4 8.5 4.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4834) TRM13 PF05206.14 CDJ46185.1 - 0.034 13.7 0.6 0.051 13.1 0.6 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 TFIIA PF03153.13 CDJ46185.1 - 0.058 13.4 28.1 0.073 13.1 28.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ46185.1 - 2.7 7.6 12.4 4.9 6.7 12.4 1.4 1 0 0 1 1 1 0 Spt20 family FHIPEP PF00771.20 CDJ46185.1 - 4.8 5.5 7.1 0.21 10.0 1.8 1.4 2 0 0 2 2 2 0 FHIPEP family CLPTM1 PF05602.12 CDJ46186.1 - 5.8e-17 61.8 0.0 2e-09 37.0 0.1 3.3 3 0 0 3 3 3 3 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF5345 PF17280.2 CDJ46186.1 - 0.018 15.0 1.3 3.3 7.7 0.0 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5345) AMO PF02461.16 CDJ46186.1 - 0.029 14.2 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase Tim54 PF11711.8 CDJ46186.1 - 0.087 11.6 2.7 0.16 10.7 2.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 CDJ46186.1 - 0.12 10.7 0.2 0.19 10.0 0.2 1.4 1 0 0 1 1 1 0 CDC45-like protein RskA PF10099.9 CDJ46186.1 - 0.24 11.7 8.5 0.17 12.2 2.4 2.8 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Merozoite_SPAM PF07133.11 CDJ46186.1 - 0.39 10.7 13.5 0.78 9.7 13.5 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) GEN1_C PF18380.1 CDJ46186.1 - 0.87 10.5 4.9 2.1 9.3 4.9 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain RAB3GAP2_N PF14655.6 CDJ46188.1 - 0.02 14.1 6.2 0.024 13.9 6.2 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Eaf7 PF07904.13 CDJ46188.1 - 0.1 13.0 2.4 0.18 12.2 2.4 1.4 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 DUF4048 PF13257.6 CDJ46188.1 - 0.11 12.3 19.4 0.1 12.4 18.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4048) RskA PF10099.9 CDJ46188.1 - 2.4 8.4 44.1 6e+03 -2.7 44.1 2.2 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Coilin_N PF15862.5 CDJ46188.1 - 7.5 6.4 16.2 4.4 7.1 10.7 2.1 2 0 0 2 2 2 0 Coilin N-terminus RskA PF10099.9 CDJ46189.1 - 1.8e-05 25.1 36.3 0.00056 20.2 12.9 9.4 3 2 4 7 7 7 3 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ46189.1 - 0.0049 15.9 8.6 0.0049 15.9 8.6 6.8 6 2 0 6 6 6 3 Protein of unknown function (DUF2722) DUF1635 PF07795.11 CDJ46190.1 - 0.012 15.5 6.3 0.012 15.5 6.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1635) DUF2722 PF10846.8 CDJ46190.1 - 0.43 9.5 9.1 7.5 5.4 6.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ46190.1 - 3.9 7.0 18.9 2.1 7.9 8.7 2.2 2 0 0 2 2 2 0 Spt20 family DDHD PF02862.17 CDJ46191.1 - 6.9e-05 23.1 1.0 6.9e-05 23.1 1.0 1.2 1 0 0 1 1 1 1 DDHD domain PTPRCAP PF15713.5 CDJ46191.1 - 0.00066 20.0 14.0 0.0017 18.6 14.0 1.7 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated FAM176 PF14851.6 CDJ46191.1 - 0.0013 18.4 4.9 0.0019 17.9 4.9 1.3 1 0 0 1 1 1 1 FAM176 family G0-G1_switch_2 PF15103.6 CDJ46191.1 - 0.0032 17.8 5.8 0.0068 16.8 5.8 1.5 1 0 0 1 1 1 1 G0/G1 switch protein 2 CTU2 PF10288.9 CDJ46191.1 - 0.0034 17.6 6.7 0.005 17.1 6.7 1.4 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 CPSF100_C PF13299.6 CDJ46191.1 - 0.01 16.0 8.0 0.019 15.2 8.0 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Velvet PF11754.8 CDJ46191.1 - 0.011 15.7 5.5 0.014 15.4 5.5 1.2 1 0 0 1 1 1 0 Velvet factor RNA_pol_Rpc4 PF05132.14 CDJ46191.1 - 0.013 15.9 5.9 0.013 15.9 5.9 2.0 2 0 0 2 2 1 0 RNA polymerase III RPC4 Eapp_C PF10238.9 CDJ46191.1 - 0.015 15.4 12.8 0.024 14.7 12.8 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Pex14_N PF04695.13 CDJ46191.1 - 0.016 15.9 14.1 0.016 15.9 14.1 2.3 2 1 1 3 3 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIP PF07454.11 CDJ46191.1 - 0.02 14.3 13.0 0.026 14.0 13.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 CDJ46191.1 - 0.024 14.8 15.4 0.031 14.4 15.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF913 PF06025.12 CDJ46191.1 - 0.024 13.6 4.7 0.028 13.4 4.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4683 PF15735.5 CDJ46191.1 - 0.026 14.2 6.5 0.033 13.8 6.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) Presenilin PF01080.17 CDJ46191.1 - 0.027 13.2 15.1 0.035 12.9 15.1 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ46191.1 - 0.027 14.3 13.1 0.035 13.9 13.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AIF_C PF14721.6 CDJ46191.1 - 0.029 14.7 6.9 0.055 13.8 6.9 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FAM76 PF16046.5 CDJ46191.1 - 0.032 13.6 13.0 0.041 13.2 13.0 1.1 1 0 0 1 1 1 0 FAM76 protein CDC45 PF02724.14 CDJ46191.1 - 0.038 12.3 11.7 0.045 12.0 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.10 CDJ46191.1 - 0.041 14.0 8.8 0.067 13.3 8.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BORG_CEP PF14957.6 CDJ46191.1 - 0.043 15.0 4.6 0.062 14.5 4.6 1.3 1 0 0 1 1 1 0 Cdc42 effector Dynamin_N PF00350.23 CDJ46191.1 - 0.05 13.7 5.6 0.073 13.1 5.6 1.2 1 0 0 1 1 1 0 Dynamin family GAGA_bind PF06217.12 CDJ46191.1 - 0.052 13.8 6.9 0.069 13.4 6.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Methyltransf_32 PF13679.6 CDJ46191.1 - 0.055 13.5 8.8 0.09 12.8 8.8 1.3 1 0 0 1 1 1 0 Methyltransferase domain Otopetrin PF03189.13 CDJ46191.1 - 0.07 11.9 0.5 0.069 12.0 0.5 1.1 1 0 0 1 1 1 0 Otopetrin DUF3295 PF11702.8 CDJ46191.1 - 0.084 12.2 13.5 0.11 11.8 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) SID-1_RNA_chan PF13965.6 CDJ46191.1 - 0.095 11.1 2.0 0.12 10.8 2.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 CDJ46191.1 - 0.097 11.7 11.4 0.12 11.4 11.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 TRAP_alpha PF03896.16 CDJ46191.1 - 0.1 11.8 5.4 0.14 11.3 5.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FHIPEP PF00771.20 CDJ46191.1 - 0.1 11.0 3.6 0.19 10.1 3.6 1.5 1 0 0 1 1 1 0 FHIPEP family Lin-8 PF03353.15 CDJ46191.1 - 0.12 11.9 17.5 0.16 11.5 17.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FAM91_C PF14648.6 CDJ46191.1 - 0.13 11.0 2.7 0.16 10.8 2.7 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Dpy19 PF10034.9 CDJ46191.1 - 0.18 10.0 0.1 0.19 9.9 0.1 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF1980 PF09323.10 CDJ46191.1 - 0.18 11.7 5.9 0.27 11.1 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) HemX PF04375.14 CDJ46191.1 - 0.26 10.5 25.9 0.44 9.8 25.9 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SAE2 PF08573.10 CDJ46191.1 - 0.33 12.1 13.0 0.64 11.2 13.0 1.5 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus EMC3_TMCO1 PF01956.16 CDJ46191.1 - 0.35 10.6 5.2 0.46 10.2 5.2 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Sin_N PF04801.13 CDJ46191.1 - 0.38 9.9 22.1 0.48 9.6 22.1 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF4638 PF15472.6 CDJ46191.1 - 0.39 10.4 9.8 0.49 10.1 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) LRRC37AB_C PF14914.6 CDJ46191.1 - 0.46 10.4 10.8 0.66 9.9 10.8 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain EPL1 PF10513.9 CDJ46191.1 - 0.46 10.9 13.3 0.69 10.3 13.3 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Ndc1_Nup PF09531.10 CDJ46191.1 - 0.49 9.0 8.8 0.56 8.8 8.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bud13 PF09736.9 CDJ46191.1 - 0.5 10.7 18.4 0.74 10.2 18.4 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Peroxin-13_N PF04088.13 CDJ46191.1 - 0.52 10.6 4.2 0.81 10.0 4.2 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region O-antigen_lig PF13425.6 CDJ46191.1 - 0.54 9.0 2.5 0.67 8.7 2.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein AAA_23 PF13476.6 CDJ46191.1 - 0.56 10.7 15.1 0.73 10.3 15.1 1.1 1 0 0 1 1 1 0 AAA domain DUF2151 PF10221.9 CDJ46191.1 - 0.62 8.6 9.2 0.79 8.2 9.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator MPM1 PF17234.2 CDJ46191.1 - 0.62 10.3 14.3 0.94 9.7 14.3 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 PAT1 PF09770.9 CDJ46191.1 - 0.62 8.3 20.7 0.76 8.0 20.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PIG-S PF10510.9 CDJ46191.1 - 0.63 8.8 7.9 0.82 8.4 7.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein CBP_BcsG PF11658.8 CDJ46191.1 - 0.64 8.3 6.6 0.95 7.8 6.6 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG TFB6 PF17110.5 CDJ46191.1 - 0.72 9.6 10.6 1.1 9.0 10.6 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RPN2_C PF18004.1 CDJ46191.1 - 0.74 9.7 15.0 1.2 9.0 15.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4820 PF16091.5 CDJ46191.1 - 0.77 9.1 10.2 1.3 8.4 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) eIF-3_zeta PF05091.12 CDJ46191.1 - 0.86 8.5 19.2 1.1 8.2 19.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MMR1 PF08505.10 CDJ46191.1 - 0.92 9.8 16.3 1.3 9.3 16.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein EIIBC-GUT_N PF03612.14 CDJ46191.1 - 1.1 9.0 13.3 2.2 8.0 13.3 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus NPR3 PF03666.13 CDJ46191.1 - 1.1 7.9 13.1 1.4 7.7 13.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Serinc PF03348.15 CDJ46191.1 - 1.2 8.0 7.4 1.6 7.6 7.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Tim54 PF11711.8 CDJ46191.1 - 1.2 7.9 13.7 1.6 7.5 13.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4746 PF15928.5 CDJ46191.1 - 1.3 8.4 11.8 1.7 8.0 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Band_3_cyto PF07565.13 CDJ46191.1 - 1.5 8.6 12.0 2.1 8.1 12.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Cellulose_synt PF03552.14 CDJ46191.1 - 1.5 7.2 3.6 1.8 6.9 3.6 1.1 1 0 0 1 1 1 0 Cellulose synthase Paf1 PF03985.13 CDJ46191.1 - 1.6 7.6 22.7 2.1 7.3 22.7 1.1 1 0 0 1 1 1 0 Paf1 Gti1_Pac2 PF09729.9 CDJ46191.1 - 1.7 8.7 11.4 2.3 8.3 11.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Peptidase_S64 PF08192.11 CDJ46191.1 - 1.7 7.0 12.3 2.1 6.7 12.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 YABBY PF04690.13 CDJ46191.1 - 1.8 9.1 9.5 2.8 8.5 9.5 1.3 1 0 0 1 1 1 0 YABBY protein Neur_chan_memb PF02932.16 CDJ46191.1 - 1.9 8.5 11.1 2.5 8.1 11.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDM10 PF12519.8 CDJ46191.1 - 2.1 7.1 11.3 2.6 6.8 11.3 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 NARP1 PF12569.8 CDJ46191.1 - 2.1 7.1 13.8 2.8 6.8 13.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PPL5 PF18168.1 CDJ46191.1 - 2.3 7.4 10.1 3.1 7.0 10.1 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Membralin PF09746.9 CDJ46191.1 - 2.3 7.1 7.2 3 6.8 7.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein FAM60A PF15396.6 CDJ46191.1 - 2.4 8.1 10.3 3.4 7.6 10.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CLN3 PF02487.17 CDJ46191.1 - 2.7 7.0 12.0 4.7 6.2 12.0 1.4 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 CDJ46191.1 - 2.7 6.7 11.1 3.5 6.4 11.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 CDJ46191.1 - 2.8 6.0 14.3 3.4 5.7 14.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pal1 PF08316.11 CDJ46191.1 - 3 8.6 8.1 5.5 7.8 8.1 1.4 1 0 0 1 1 1 0 Pal1 cell morphology protein Paramyxo_ncap PF00973.19 CDJ46191.1 - 3.2 6.6 10.2 4 6.2 10.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4457 PF14652.6 CDJ46191.1 - 3.6 6.8 6.1 4.7 6.4 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) TERB2 PF15101.6 CDJ46191.1 - 3.7 7.5 21.2 5.8 6.9 21.2 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Sec62 PF03839.16 CDJ46191.1 - 4 6.9 11.1 5.4 6.5 11.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1764 PF08576.10 CDJ46191.1 - 4.1 8.4 14.9 7.2 7.6 14.9 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Sporozoite_P67 PF05642.11 CDJ46191.1 - 4.1 5.4 23.9 6.3 4.8 23.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_U57 PF05582.12 CDJ46191.1 - 4.8 6.4 11.3 7 5.8 11.3 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Pinin_SDK_memA PF04696.13 CDJ46191.1 - 5.1 7.2 32.6 7.9 6.6 32.6 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region GREB1 PF15782.5 CDJ46191.1 - 5.4 4.0 14.5 6.6 3.7 14.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RPA43_OB PF17875.1 CDJ46191.1 - 5.7 7.6 12.1 10 6.7 12.1 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Afi1 PF07792.12 CDJ46191.1 - 6 7.4 15.1 8.9 6.8 15.1 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF5523 PF17661.1 CDJ46191.1 - 6 6.5 19.8 8.6 6.0 19.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) MCU PF04678.13 CDJ46191.1 - 6.5 6.8 10.4 11 6.0 10.4 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter UPF0560 PF10577.9 CDJ46191.1 - 6.7 5.1 23.0 8.6 4.7 23.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2058 PF09831.9 CDJ46191.1 - 7.9 6.6 27.5 15 5.7 27.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF2828 PF11443.8 CDJ46191.1 - 8 4.4 16.9 11 4.0 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Connexin PF00029.19 CDJ46191.1 - 8 6.1 16.5 13 5.5 16.5 1.2 1 0 0 1 1 1 0 Connexin Folate_carrier PF01770.18 CDJ46191.1 - 8.7 5.0 8.2 13 4.4 8.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier PIP5K PF01504.18 CDJ46191.1 - 9.3 5.4 14.0 13 4.9 14.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF3408 PF11888.8 CDJ46191.1 - 9.4 6.4 20.2 16 5.7 20.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Macoilin PF09726.9 CDJ46191.1 - 9.9 4.6 15.1 16 3.9 15.1 1.3 1 0 0 1 1 1 0 Macoilin family DUF2232 PF09991.9 CDJ46192.1 - 0.00044 19.5 2.0 0.00044 19.5 2.0 2.0 1 1 2 3 3 3 1 Predicted membrane protein (DUF2232) Caldesmon PF02029.15 CDJ46192.1 - 0.4 9.4 22.9 0.48 9.1 22.9 1.2 1 0 0 1 1 1 0 Caldesmon MRP-S27 PF10037.9 CDJ46192.1 - 9.3 5.0 30.5 15 4.3 30.5 1.4 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Fanconi_A_N PF15865.5 CDJ46194.1 - 0.00063 19.3 1.2 0.031 13.7 0.1 2.2 2 0 0 2 2 2 2 Fanconi anaemia group A protein N terminus Peptidase_M4 PF01447.18 CDJ46195.1 - 0.57 10.7 5.5 0.57 10.7 0.1 3.1 3 0 0 3 3 3 0 Thermolysin metallopeptidase, catalytic domain UPF0449 PF15136.6 CDJ46196.1 - 0.099 13.1 3.6 0.081 13.4 2.0 1.7 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 GvpO PF05800.11 CDJ46196.1 - 0.15 12.0 1.6 0.17 11.9 0.0 1.8 2 1 0 2 2 2 0 Gas vesicle synthesis protein GvpO Thioredoxin PF00085.20 CDJ46197.1 - 5.5e-12 45.6 0.0 7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 CDJ46197.1 - 0.0029 17.4 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDJ46197.1 - 0.0088 16.3 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 CDJ46197.1 - 0.067 12.9 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Redoxin SDA1 PF05285.12 CDJ46198.1 - 0.082 12.3 33.2 0.2 11.0 2.5 2.2 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 CDJ46198.1 - 0.41 8.9 39.8 0.36 9.1 3.7 2.1 2 0 0 2 2 2 0 CDC45-like protein NPR3 PF03666.13 CDJ46198.1 - 0.73 8.6 34.0 1.6 7.5 4.3 2.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Virul_Fac PF10139.9 CDJ46198.1 - 0.89 7.7 28.8 0.04 12.1 4.6 2.3 2 0 0 2 2 2 0 Putative bacterial virulence factor Rtf2 PF04641.12 CDJ46198.1 - 1.1 8.6 37.7 1.6 8.0 6.6 2.5 2 0 0 2 2 2 0 Rtf2 RING-finger Lin-8 PF03353.15 CDJ46198.1 - 1.2 8.7 46.5 0.74 9.3 29.0 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF2151 PF10221.9 CDJ46198.1 - 1.5 7.4 27.6 0.027 13.1 0.5 2.1 2 0 0 2 2 2 0 Cell cycle and development regulator DUF2052 PF09747.9 CDJ46198.1 - 1.6 8.8 49.8 0.29 11.2 8.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CCSAP PF15748.5 CDJ46198.1 - 1.9 8.6 50.1 1.4 9.0 8.9 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Nha1_C PF08619.10 CDJ46198.1 - 3.2 6.9 41.2 0.053 12.7 3.4 2.4 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Apt1 PF10351.9 CDJ46198.1 - 5.8 5.7 27.9 4.5 6.0 5.6 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Vfa1 PF08432.10 CDJ46198.1 - 6.4 7.1 51.1 10 6.4 32.3 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SLC12 PF03522.15 CDJ46198.1 - 7.2 5.5 45.5 0.75 8.8 6.2 2.1 2 0 0 2 2 2 0 Solute carrier family 12 DUF4647 PF15504.6 CDJ46198.1 - 7.7 5.5 44.1 0.059 12.5 5.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) Raftlin PF15250.6 CDJ46198.1 - 9.5 4.8 36.1 2 7.1 23.7 2.1 2 0 0 2 2 2 0 Raftlin Utp14 PF04615.13 CDJ46199.1 - 0.12 10.9 0.0 0.12 10.9 0.0 11.1 5 4 3 9 9 9 0 Utp14 protein Ribosomal_L39 PF00832.20 CDJ46200.1 - 1.2e-20 72.9 11.6 1.7e-20 72.3 11.6 1.2 1 0 0 1 1 1 1 Ribosomal L39 protein GRP PF07172.11 CDJ46200.1 - 0.16 12.7 0.3 2.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Glycine rich protein family TFIIA PF03153.13 CDJ46200.1 - 1.1 9.2 16.3 1.3 9.0 16.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tic110 PF16940.5 CDJ46200.1 - 3.5 6.0 8.5 4.4 5.7 8.5 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF1180 PF06679.12 CDJ46200.1 - 9.4 6.6 9.3 30 5.0 8.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Presenilin PF01080.17 CDJ46201.1 - 5.5 5.7 43.6 6.3 5.5 43.6 1.0 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ46202.1 - 1.7e-07 30.6 44.2 8.7e-05 21.6 5.7 3.8 3 0 0 3 3 3 3 Protein of unknown function (DUF2722) DUF1645 PF07816.11 CDJ46202.1 - 0.0034 18.0 1.9 0.0034 18.0 1.9 4.9 5 0 0 5 5 5 2 Protein of unknown function (DUF1645) RskA PF10099.9 CDJ46202.1 - 0.011 16.0 0.0 0.011 16.0 0.0 8.2 4 2 2 6 6 5 0 Anti-sigma-K factor rskA TCP PF03634.13 CDJ46202.1 - 0.013 16.0 3.9 0.013 16.0 3.9 4.6 4 1 0 4 4 3 0 TCP family transcription factor BRF1 PF07741.13 CDJ46202.1 - 0.064 13.6 20.8 0.86 10.0 1.5 3.7 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Rrp15p PF07890.12 CDJ46202.1 - 0.14 12.5 26.1 0.83 10.0 3.9 3.8 3 0 0 3 3 3 0 Rrp15p Toprim_2 PF13155.6 CDJ46202.1 - 0.18 12.2 0.1 0.18 12.2 0.1 4.0 3 1 1 4 4 3 0 Toprim-like Afi1 PF07792.12 CDJ46202.1 - 0.32 11.5 22.1 1.4 9.4 0.7 3.4 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking eIF-3_zeta PF05091.12 CDJ46202.1 - 0.39 9.6 25.8 0.48 9.3 0.9 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1266 PF06889.11 CDJ46202.1 - 0.59 10.2 15.3 3 7.9 2.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1266) Slu7 PF11708.8 CDJ46202.1 - 0.68 9.6 26.3 0.55 9.9 3.3 3.2 3 0 0 3 3 3 0 Pre-mRNA splicing Prp18-interacting factor SpoIIP PF07454.11 CDJ46202.1 - 1.8 7.9 24.9 2.9 7.3 1.8 3.2 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) PTPRCAP PF15713.5 CDJ46202.1 - 1.9 8.7 25.3 2.5 8.4 2.8 4.0 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated MAT1 PF06391.13 CDJ46202.1 - 2.4 8.0 38.5 1.1 9.0 3.3 3.3 3 0 0 3 3 3 0 CDK-activating kinase assembly factor MAT1 Thg1C PF14413.6 CDJ46202.1 - 4.2 7.6 19.7 4.4 7.5 1.7 3.4 3 0 0 3 3 3 0 Thg1 C terminal domain Mak16 PF04874.14 CDJ46202.1 - 4.5 7.9 17.7 3.2 8.4 1.1 3.5 3 0 0 3 3 3 0 Mak16 protein C-terminal region Suf PF05843.14 CDJ46202.1 - 5 7.0 41.2 0.48 10.3 2.5 3.5 2 1 0 3 3 3 0 Suppressor of forked protein (Suf) Lin-8 PF03353.15 CDJ46202.1 - 6.4 6.2 37.0 0.79 9.2 1.8 3.6 4 0 0 4 4 4 0 Ras-mediated vulval-induction antagonist RPA43_OB PF17875.1 CDJ46202.1 - 8.3 7.1 16.6 20 5.9 0.8 3.5 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Ferlin_C PF16165.5 CDJ46202.1 - 9 6.2 7.0 76 3.2 0.0 3.1 3 0 0 3 3 3 0 Ferlin C-terminus RED_N PF07808.13 CDJ46203.1 - 0.0037 16.9 1.6 0.0037 16.9 1.6 11.9 9 2 3 12 12 12 1 RED-like protein N-terminal region RskA PF10099.9 CDJ46203.1 - 0.021 15.1 0.5 0.021 15.1 0.5 15.5 1 1 12 14 14 14 0 Anti-sigma-K factor rskA tRNA-synt_1 PF00133.22 CDJ46204.1 - 1e-13 50.5 0.0 1e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ46205.1 - 1.4e-24 86.8 0.6 4.9e-24 85.0 0.0 2.1 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 CDJ46205.1 - 2.6e-13 49.1 0.0 1.8e-06 26.5 0.0 2.4 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CDJ46205.1 - 0.0032 16.8 0.1 0.19 11.1 0.0 2.5 2 1 1 3 3 3 2 tRNA synthetases class I (C) catalytic domain Med3 PF11593.8 CDJ46205.1 - 3.5 6.7 20.5 0.48 9.6 15.9 1.8 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal zf-NADH-PPase PF09297.11 CDJ46210.1 - 0.33 10.7 2.9 0.49 10.1 0.8 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RRM_1 PF00076.22 CDJ46211.1 - 4.7e-07 29.5 0.0 8.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ46211.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif FliD_N PF02465.18 CDJ46211.1 - 0.2 12.4 3.1 6.1 7.6 1.0 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Lactamase_B_2 PF12706.7 CDJ46212.1 - 2.8e-07 30.3 2.5 2.8e-05 23.7 0.3 3.7 3 1 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ46212.1 - 0.00015 21.9 0.2 0.0019 18.3 0.2 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Dehydrin PF00257.19 CDJ46213.1 - 0.18 12.3 5.2 0.32 11.5 0.1 2.3 2 0 0 2 2 2 0 Dehydrin RNA_pol_Rpb2_6 PF00562.28 CDJ46216.1 - 2.5e-115 385.7 0.0 3.3e-115 385.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDJ46216.1 - 5.1e-27 94.7 0.0 9.1e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CDJ46216.1 - 2.1e-19 69.7 0.0 4e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 CDJ46216.1 - 5.7e-15 55.2 0.0 1.5e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CDJ46216.1 - 9.5e-05 22.3 0.0 0.00036 20.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 CDJ46216.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Methyltransf_10 PF05971.12 CDJ46219.1 - 9.8e-34 117.0 6.0 3.4e-20 72.6 3.4 4.5 2 2 0 2 2 2 2 RNA methyltransferase CCDC53 PF10152.9 CDJ46219.1 - 0.012 16.0 1.2 0.012 16.0 1.2 5.8 4 1 0 4 4 4 0 Subunit CCDC53 of WASH complex MecA PF05389.12 CDJ46219.1 - 0.013 15.1 1.4 0.013 15.1 1.4 2.9 2 1 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF4667 PF15700.5 CDJ46219.1 - 0.029 14.5 0.0 0.029 14.5 0.0 4.5 4 1 0 4 4 4 0 Domain of unknown function (DUF4667) AIF_C PF14721.6 CDJ46219.1 - 0.038 14.3 0.5 0.038 14.3 0.5 4.6 4 1 0 4 4 4 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SID-1_RNA_chan PF13965.6 CDJ46219.1 - 0.38 9.1 0.0 0.38 9.1 0.0 2.6 3 0 0 3 3 3 0 dsRNA-gated channel SID-1 AAA_23 PF13476.6 CDJ46220.1 - 8.7e-07 29.6 9.9 8.7e-07 29.6 9.9 1.2 1 0 0 1 1 1 1 AAA domain LMBR1 PF04791.16 CDJ46220.1 - 1 8.2 10.9 1.1 8.1 10.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein eIF-3_zeta PF05091.12 CDJ46220.1 - 3.2 6.6 38.9 4.5 6.1 38.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex14_N PF04695.13 CDJ46221.1 - 1.6 9.4 15.8 1.8 9.2 15.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.9 CDJ46221.1 - 7.9 6.7 11.5 9.9 6.4 11.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA LMBR1 PF04791.16 CDJ46222.1 - 0.56 9.1 6.8 0.77 8.6 6.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF572 PF04502.13 CDJ46222.1 - 0.64 9.6 31.7 0.19 11.3 20.5 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF572) CCSAP PF15748.5 CDJ46222.1 - 1.7 8.7 33.9 0.54 10.4 28.0 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF2052 PF09747.9 CDJ46222.1 - 2.4 8.2 29.4 0.77 9.9 21.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) VIR_N PF15912.5 CDJ46222.1 - 6.8 6.2 20.2 0.58 9.7 15.2 1.6 2 0 0 2 2 2 0 Virilizer, N-terminal Asp-B-Hydro_N PF05279.11 CDJ46222.1 - 7.4 6.6 30.8 1 9.3 25.6 1.8 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 CDJ46222.1 - 8.5 5.0 37.8 2.1 7.0 32.4 2.1 2 0 0 2 2 2 0 Presenilin MAP65_ASE1 PF03999.12 CDJ46223.1 - 0.0014 17.4 0.0 0.0014 17.4 0.0 11.6 9 4 3 12 12 12 2 Microtubule associated protein (MAP65/ASE1 family) DUF4757 PF15949.5 CDJ46223.1 - 2.9 8.3 0.0 2.9 8.3 0.0 14.0 13 2 1 15 15 15 0 Domain of unknown function (DUF4757) Mucin15 PF15672.5 CDJ46225.1 - 0.31 10.5 5.2 0.16 11.4 2.9 1.6 1 1 0 1 1 1 0 Cell-membrane associated Mucin15 GT87 PF09594.10 CDJ46226.1 - 0.0045 16.7 0.7 0.71 9.5 1.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 87 Neur_chan_memb PF02932.16 CDJ46226.1 - 0.0078 16.3 8.1 0.0081 16.2 8.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L12_N PF16320.5 CDJ46226.1 - 0.013 15.2 0.7 0.013 15.2 0.7 3.5 3 1 0 3 3 2 0 Ribosomal protein L7/L12 dimerisation domain SID-1_RNA_chan PF13965.6 CDJ46226.1 - 0.054 11.9 2.6 0.047 12.1 2.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF-3_zeta PF05091.12 CDJ46226.1 - 0.055 12.5 23.6 0.062 12.3 23.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF572 PF04502.13 CDJ46226.1 - 0.065 12.9 19.5 0.081 12.5 19.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nop53 PF07767.11 CDJ46226.1 - 0.1 11.9 29.5 0.13 11.6 29.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 CDJ46226.1 - 0.13 10.5 19.5 0.17 10.1 19.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 CDJ46226.1 - 0.15 11.0 8.3 0.14 11.1 8.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) LAP1C PF05609.12 CDJ46226.1 - 0.23 10.5 18.2 0.24 10.5 18.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 CDJ46226.1 - 0.36 7.9 16.9 0.41 7.7 16.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM60A PF15396.6 CDJ46226.1 - 0.44 10.5 20.8 0.24 11.4 19.0 1.4 2 0 0 2 2 2 0 Protein Family FAM60A SprA-related PF12118.8 CDJ46226.1 - 0.51 9.4 38.1 0.68 9.0 38.1 1.1 1 0 0 1 1 1 0 SprA-related family LMBR1 PF04791.16 CDJ46226.1 - 0.71 8.7 5.3 0.63 8.9 5.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SAPS PF04499.15 CDJ46226.1 - 0.74 8.5 13.3 0.7 8.6 13.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4719 PF15843.5 CDJ46226.1 - 0.83 9.7 3.3 1.3 9.1 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Ctr PF04145.15 CDJ46226.1 - 0.87 10.2 9.7 1.9 9.1 9.7 1.6 1 0 0 1 1 1 0 Ctr copper transporter family HemX PF04375.14 CDJ46226.1 - 0.91 8.7 35.8 1.4 8.1 35.8 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Pex14_N PF04695.13 CDJ46226.1 - 1.1 9.9 29.8 2.6 8.7 29.1 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4179 PF13786.6 CDJ46226.1 - 1.5 9.4 7.4 14 6.2 7.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) PIP5K PF01504.18 CDJ46226.1 - 2.6 7.2 14.7 4.3 6.5 14.7 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Hydin_ADK PF17213.3 CDJ46226.1 - 4.5 7.5 17.8 7.1 6.9 17.8 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain VIR_N PF15912.5 CDJ46226.1 - 5.6 6.5 14.8 7.7 6.0 14.8 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Presenilin PF01080.17 CDJ46226.1 - 5.8 5.6 30.3 7.9 5.1 30.3 1.1 1 0 0 1 1 1 0 Presenilin Ureide_permease PF07168.11 CDJ46226.1 - 8.1 5.1 11.2 15 4.2 11.2 1.4 1 0 0 1 1 1 0 Ureide permease BUD22 PF09073.10 CDJ46227.1 - 0.00013 21.5 0.0 0.00013 21.5 0.0 9.0 6 5 2 8 8 8 3 BUD22 TFIIA PF03153.13 CDJ46227.1 - 0.00073 19.6 40.8 0.00073 19.6 40.8 11.9 5 3 3 9 9 9 3 Transcription factor IIA, alpha/beta subunit SART-1 PF03343.13 CDJ46227.1 - 0.0017 17.0 15.0 0.0017 17.0 15.0 7.5 7 2 0 7 7 7 1 SART-1 family RskA PF10099.9 CDJ46227.1 - 0.0031 17.8 0.0 0.0031 17.8 0.0 23.5 5 4 13 21 21 21 5 Anti-sigma-K factor rskA RR_TM4-6 PF06459.12 CDJ46229.1 - 0.33 10.7 19.8 0.38 10.6 19.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ46229.1 - 0.36 9.5 26.2 0.4 9.4 26.2 1.1 1 0 0 1 1 1 0 Presenilin Vac7 PF12751.7 CDJ46229.1 - 0.4 10.1 11.6 0.51 9.7 11.6 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF4045 PF13254.6 CDJ46229.1 - 1.2 8.7 16.1 1.2 8.7 16.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CrgA PF06781.12 CDJ46229.1 - 1.6 8.9 7.6 35 4.5 7.6 2.2 1 1 0 1 1 1 0 Cell division protein CrgA HCO3_cotransp PF00955.21 CDJ46229.1 - 1.8 7.3 9.8 2.1 7.0 9.8 1.1 1 0 0 1 1 1 0 HCO3- transporter family CDC45 PF02724.14 CDJ46229.1 - 2.1 6.5 17.6 2.4 6.3 17.6 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.6 CDJ46229.1 - 2.1 8.3 17.9 2.5 8.1 17.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RP-C_C PF11800.8 CDJ46229.1 - 2.5 8.1 19.5 2.7 8.0 19.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region V_ATPase_I PF01496.19 CDJ46229.1 - 4.6 5.0 26.8 5 4.9 26.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 CDJ46229.1 - 5.6 5.9 26.6 5.7 5.8 26.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ46229.1 - 9.1 5.7 28.7 11 5.5 28.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RskA PF10099.9 CDJ46230.1 - 0.046 14.0 0.0 0.046 14.0 0.0 2.1 1 1 0 2 2 2 0 Anti-sigma-K factor rskA SOBP PF15279.6 CDJ46230.1 - 0.089 13.4 29.2 0.11 13.1 29.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Roughex PF06020.11 CDJ46230.1 - 0.23 10.5 5.7 0.51 9.4 5.7 1.7 1 0 0 1 1 1 0 Drosophila roughex protein Utp14 PF04615.13 CDJ46230.1 - 0.26 9.8 15.4 0.38 9.3 15.4 1.2 1 0 0 1 1 1 0 Utp14 protein Ribosomal_60s PF00428.19 CDJ46230.1 - 0.61 10.7 16.3 0.062 13.9 11.5 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Hid1 PF12722.7 CDJ46230.1 - 0.9 7.6 21.0 1 7.4 21.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPP4R2 PF09184.11 CDJ46230.1 - 1.3 8.6 19.2 1.9 8.0 19.2 1.2 1 0 0 1 1 1 0 PPP4R2 Peptidase_S64 PF08192.11 CDJ46230.1 - 1.8 7.0 30.2 2.3 6.6 30.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 XRN_M PF17846.1 CDJ46231.1 - 0.018 14.0 22.2 0.02 13.9 22.2 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Asp-B-Hydro_N PF05279.11 CDJ46231.1 - 0.054 13.6 28.2 0.06 13.4 28.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PPP4R2 PF09184.11 CDJ46231.1 - 0.13 11.9 19.8 0.15 11.6 19.8 1.3 1 0 0 1 1 1 0 PPP4R2 Draxin PF15550.6 CDJ46231.1 - 0.17 11.7 28.4 0.21 11.5 28.4 1.1 1 0 0 1 1 1 0 Draxin DUF4776 PF16003.5 CDJ46231.1 - 0.28 10.2 30.6 0.37 9.7 30.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) CRT10 PF08728.10 CDJ46231.1 - 0.82 7.8 14.6 0.81 7.8 14.6 1.0 1 0 0 1 1 1 0 CRT10 SOBP PF15279.6 CDJ46231.1 - 1.5 9.4 37.2 2.2 8.8 37.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein SLC12 PF03522.15 CDJ46231.1 - 2.2 7.2 38.4 2.8 6.9 38.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 CDJ46231.1 - 3 6.0 33.8 4.1 5.6 33.8 1.2 1 0 0 1 1 1 0 CDC45-like protein MAT1 PF06391.13 CDJ46231.1 - 4.1 7.2 43.3 7.3 6.4 43.3 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 PAT1 PF09770.9 CDJ46231.1 - 4.5 5.4 58.6 5.2 5.2 58.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MDM10 PF12519.8 CDJ46231.1 - 5 5.9 31.2 6.9 5.4 31.2 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 GAGA_bind PF06217.12 CDJ46231.1 - 7.1 6.8 33.8 11 6.2 33.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family BSP_II PF05432.11 CDJ46231.1 - 7.1 6.2 20.7 8.9 5.9 20.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF966 PF06136.13 CDJ46231.1 - 9.9 5.8 36.8 14 5.3 36.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Spore_coat_CotO PF14153.6 CDJ46232.1 - 1.1 9.2 26.4 1.3 9.0 26.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Asp-B-Hydro_N PF05279.11 CDJ46232.1 - 1.2 9.2 14.7 1.2 9.1 14.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region eIF-3_zeta PF05091.12 CDJ46232.1 - 1.4 7.8 23.6 1.6 7.6 23.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 CDJ46232.1 - 1.9 8.3 25.3 2.3 8.0 25.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.8 CDJ46232.1 - 3 6.9 40.4 4.2 6.4 40.4 1.2 1 0 0 1 1 1 0 SprA-related family Serinc PF03348.15 CDJ46232.1 - 3.2 6.6 13.3 4.8 6.0 13.3 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4407 PF14362.6 CDJ46232.1 - 9.6 5.5 15.9 10 5.3 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Thioredoxin PF00085.20 CDJ46233.1 - 8.6e-11 41.7 0.1 6.7e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin DAHP_synth_2 PF01474.16 CDJ46234.1 - 2.9e-42 144.7 0.1 3.6e-42 144.4 0.1 1.1 1 0 0 1 1 1 1 Class-II DAHP synthetase family Spt20 PF12090.8 CDJ46234.1 - 1.2 8.7 9.6 2.4 7.7 9.6 1.4 1 0 0 1 1 1 0 Spt20 family PNP_UDP_1 PF01048.20 CDJ46235.1 - 4.9e-09 35.8 0.0 7.5e-08 31.9 0.0 2.0 1 1 1 2 2 2 2 Phosphorylase superfamily zf-C3HC4_3 PF13920.6 CDJ46237.1 - 0.014 15.2 16.6 0.04 13.8 16.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SUIM_assoc PF16619.5 CDJ46237.1 - 0.097 12.7 12.1 0.13 12.3 3.2 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ46237.1 - 0.11 12.5 9.2 0.17 11.9 9.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Prok-RING_4 PF14447.6 CDJ46237.1 - 0.2 11.5 12.9 0.62 10.0 12.9 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF5536 PF17688.1 CDJ46237.1 - 0.52 10.2 25.6 0.17 11.7 7.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5536) Spt20 PF12090.8 CDJ46237.1 - 1.9 8.0 9.9 1.4 8.5 7.0 1.9 2 0 0 2 2 2 0 Spt20 family zf-RING_2 PF13639.6 CDJ46237.1 - 2.1 8.7 14.7 3.3 8.1 14.7 1.3 1 0 0 1 1 1 0 Ring finger domain CCDC53 PF10152.9 CDJ46237.1 - 4.3 7.7 8.8 1.7 9.1 2.3 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex zf-RING_5 PF14634.6 CDJ46237.1 - 8.8 6.4 16.7 27 4.8 16.7 1.9 1 1 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.25 CDJ46238.1 - 2.7e-06 26.9 0.0 6.3e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Spt20 PF12090.8 CDJ46238.1 - 5.3 6.6 44.4 0.033 13.8 8.5 4.2 2 1 1 3 3 3 0 Spt20 family Dcc1 PF09724.9 CDJ46239.1 - 1.3e-06 28.0 5.8 0.0088 15.4 1.8 2.8 2 1 0 2 2 2 2 Sister chromatid cohesion protein Dcc1 Spt20 PF12090.8 CDJ46239.1 - 8.7 5.9 79.8 0.021 14.4 11.0 5.9 6 0 0 6 6 6 0 Spt20 family MACPF PF01823.19 CDJ46240.1 - 0.27 11.3 0.0 0.27 11.3 0.0 3.0 3 0 0 3 3 3 0 MAC/Perforin domain CLZ PF16526.5 CDJ46242.1 - 0.11 12.8 0.3 0.22 11.9 0.3 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pkinase PF00069.25 CDJ46243.1 - 1.5e-23 83.5 0.0 5.5e-23 81.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ46243.1 - 1.1e-11 44.5 0.0 2.1e-10 40.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 CDJ46243.1 - 1.2e-10 41.7 0.1 3.3e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ46243.1 - 3e-08 33.4 0.7 7.2e-06 25.8 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ46243.1 - 2.4e-07 30.1 0.3 0.021 14.8 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDJ46243.1 - 6.6e-07 28.4 0.7 0.054 13.1 0.0 3.2 4 0 0 4 4 4 2 EF hand Kinase-like PF14531.6 CDJ46243.1 - 0.00043 19.7 0.0 0.0013 18.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like EF-hand_5 PF13202.6 CDJ46243.1 - 0.00072 19.0 4.2 0.22 11.1 0.6 2.7 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 CDJ46243.1 - 1.1 9.3 2.3 7 6.7 0.1 2.9 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Topoisom_bac PF01131.20 CDJ46244.1 - 6e-72 242.9 0.0 2.1e-32 112.6 0.0 4.2 3 1 0 3 3 3 3 DNA topoisomerase Toprim PF01751.22 CDJ46244.1 - 1.6e-15 57.1 0.0 3.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF1043 PF06295.12 CDJ46246.1 - 0.013 15.5 4.5 0.013 15.5 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) AnmK PF03702.14 CDJ46246.1 - 0.033 13.3 0.1 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase AAA_23 PF13476.6 CDJ46246.1 - 0.074 13.5 1.5 0.38 11.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.6 CDJ46246.1 - 0.08 12.3 9.8 0.19 11.1 9.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ACOX PF01756.19 CDJ46246.1 - 0.63 9.6 4.5 1 8.9 4.5 1.3 1 0 0 1 1 1 0 Acyl-CoA oxidase Spc7 PF08317.11 CDJ46246.1 - 7.7 5.3 12.4 13 4.5 12.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Amidinotransf PF02274.17 CDJ46248.1 - 0.1 11.7 0.3 0.15 11.1 0.3 1.1 1 0 0 1 1 1 0 Amidinotransferase NESP55 PF06390.12 CDJ46250.1 - 1.4 8.4 28.8 2.2 7.8 28.8 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pkinase PF00069.25 CDJ46251.1 - 2.2e-16 60.0 1.4 9.1e-12 44.9 0.0 2.5 2 1 1 3 3 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ46251.1 - 1.8e-08 34.0 1.3 0.0022 17.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase RskA PF10099.9 CDJ46251.1 - 0.021 15.1 16.5 0.021 15.1 16.5 3.4 2 1 0 2 2 1 0 Anti-sigma-K factor rskA Phosducin PF02114.16 CDJ46251.1 - 0.056 12.4 0.0 0.056 12.4 0.0 2.4 4 0 0 4 4 3 0 Phosducin TAF4 PF05236.14 CDJ46251.1 - 0.58 9.9 13.4 0.15 11.8 7.8 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family EPL1 PF10513.9 CDJ46251.1 - 1.3 9.4 9.7 1.9 8.8 9.7 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF4770 PF15994.5 CDJ46251.1 - 3.2 8.0 8.9 4.5 7.5 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Sin_N PF04801.13 CDJ46251.1 - 5.7 6.0 17.0 8.1 5.5 17.0 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Presenilin PF01080.17 CDJ46251.1 - 5.9 5.6 10.5 7.8 5.2 10.5 1.1 1 0 0 1 1 1 0 Presenilin DUF4179 PF13786.6 CDJ46251.1 - 7.3 7.1 0.0 7.3 7.1 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4179) Rotamase_2 PF13145.6 CDJ46251.1 - 9.5 7.1 15.4 5.6 7.8 0.4 2.8 3 0 0 3 3 2 0 PPIC-type PPIASE domain SseC PF04888.12 CDJ46252.1 - 0.0029 17.3 21.1 0.0038 16.9 21.1 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Amastin PF07344.11 CDJ46252.1 - 0.021 14.6 3.9 0.035 13.9 3.9 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein Pox_A12 PF04651.13 CDJ46252.1 - 1.4 8.9 10.4 2 8.4 10.4 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein RskA PF10099.9 CDJ46253.1 - 0.01 16.1 1.0 0.01 16.1 1.0 5.0 1 1 3 4 4 4 0 Anti-sigma-K factor rskA Pep3_Vps18 PF05131.14 CDJ46254.1 - 2.3e-05 24.3 0.0 2.3e-05 24.3 0.0 2.1 2 0 0 2 2 1 1 Pep3/Vps18/deep orange family SR-25 PF10500.9 CDJ46254.1 - 0.0026 17.4 11.7 0.0026 17.4 11.7 6.1 6 0 0 6 6 6 2 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ46254.1 - 0.0027 17.8 20.5 0.0027 17.8 20.5 3.2 3 1 0 3 3 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ46254.1 - 0.0046 17.1 8.3 0.39 10.9 4.1 2.7 2 0 0 2 2 2 2 DDHD domain Vps39_2 PF10367.9 CDJ46254.1 - 0.0057 17.1 0.5 0.0057 17.1 0.5 2.8 2 0 0 2 2 1 1 Vacuolar sorting protein 39 domain 2 EPL1 PF10513.9 CDJ46254.1 - 0.0067 16.8 8.8 0.02 15.3 2.0 2.5 2 0 0 2 2 2 1 Enhancer of polycomb-like SPX PF03105.19 CDJ46254.1 - 0.013 15.4 0.8 0.013 15.4 0.8 2.6 2 1 0 2 2 2 0 SPX domain Med15 PF09606.10 CDJ46254.1 - 0.17 10.5 28.9 0.079 11.6 19.6 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Apt1 PF10351.9 CDJ46254.1 - 0.22 10.3 22.7 0.26 10.1 4.6 2.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Gti1_Pac2 PF09729.9 CDJ46254.1 - 0.32 11.1 11.3 9.5 6.3 0.1 2.6 2 0 0 2 2 2 0 Gti1/Pac2 family Ctr PF04145.15 CDJ46254.1 - 0.46 11.1 5.3 19 5.8 2.6 2.9 2 0 0 2 2 2 0 Ctr copper transporter family DUF572 PF04502.13 CDJ46254.1 - 0.5 9.9 13.6 1.5 8.3 8.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) BRF1 PF07741.13 CDJ46254.1 - 1.1 9.6 7.4 0.3 11.4 1.6 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain CPSF100_C PF13299.6 CDJ46254.1 - 1.2 9.3 7.0 0.57 10.3 1.1 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Folliculin PF11704.8 CDJ46254.1 - 2.5 7.9 9.6 5.7 6.8 4.5 2.8 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Rgp1 PF08737.10 CDJ46254.1 - 3 6.9 14.3 4.7 6.3 8.8 2.3 2 0 0 2 2 2 0 Rgp1 PRC2_HTH_1 PF18118.1 CDJ46254.1 - 3.9 8.3 6.9 1.4 9.8 0.9 2.5 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Spt20 PF12090.8 CDJ46254.1 - 5.2 6.6 51.2 5.8 6.4 7.0 2.5 2 0 0 2 2 2 0 Spt20 family Neur_chan_memb PF02932.16 CDJ46254.1 - 5.8 6.9 10.2 25 4.8 7.0 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 CDJ46254.1 - 7.9 5.3 43.0 0.0091 15.0 21.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF775 PF05603.12 CDJ46254.1 - 9.1 5.8 20.1 6.1 6.3 10.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF775) DUF4628 PF15429.6 CDJ46255.1 - 0.45 10.1 11.5 0.47 10.1 11.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) FYDLN_acid PF09538.10 CDJ46255.1 - 1.4 9.6 21.9 1.7 9.4 21.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDC27 PF09507.10 CDJ46255.1 - 3.7 6.8 22.0 4.1 6.7 22.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RNA_pol_3_Rpc31 PF11705.8 CDJ46255.1 - 3.7 7.7 36.5 4.2 7.6 36.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RNA_pol_Rpc4 PF05132.14 CDJ46255.1 - 8.7 6.8 15.5 9.7 6.6 15.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 PCI PF01399.27 CDJ46256.1 - 2.7e-16 60.0 0.0 3.9e-15 56.2 0.0 2.5 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CDJ46256.1 - 9.7e-13 48.0 0.4 3.1e-12 46.4 0.4 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF2379 PF09543.10 CDJ46256.1 - 6.9 6.9 11.6 2.3 8.4 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) DUF2722 PF10846.8 CDJ46258.1 - 0.00021 20.4 14.7 0.00022 20.3 14.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ46258.1 - 0.0021 18.1 22.5 0.0027 17.8 22.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Shadoo PF14999.6 CDJ46258.1 - 0.0086 16.2 8.5 0.013 15.6 8.5 1.4 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective DUF3449 PF11931.8 CDJ46258.1 - 0.01 15.7 4.9 0.017 14.9 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) ABC2_membrane_2 PF12679.7 CDJ46258.1 - 0.016 14.5 3.2 0.03 13.6 3.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein RAB3GAP2_C PF14656.6 CDJ46258.1 - 0.034 12.4 6.0 0.05 11.8 6.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus UPF0560 PF10577.9 CDJ46258.1 - 0.042 12.4 13.5 0.054 12.0 13.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Transformer PF06495.11 CDJ46258.1 - 0.043 13.9 6.2 0.055 13.6 6.2 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein NPR3 PF03666.13 CDJ46258.1 - 0.045 12.5 7.9 0.043 12.6 7.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RLL PF10036.9 CDJ46258.1 - 0.048 13.5 13.1 0.059 13.2 13.1 1.1 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Dynactin_p62 PF05502.13 CDJ46258.1 - 0.066 12.0 7.0 0.07 11.9 7.0 1.2 1 0 0 1 1 1 0 Dynactin p62 family FAM176 PF14851.6 CDJ46258.1 - 0.078 12.6 4.3 0.13 11.9 4.3 1.5 1 0 0 1 1 1 0 FAM176 family SLC12 PF03522.15 CDJ46258.1 - 0.14 11.2 9.1 0.14 11.1 9.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 tRNA_synt_1c_R2 PF04557.15 CDJ46258.1 - 0.14 13.1 12.0 0.81 10.7 8.5 2.3 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Spt20 PF12090.8 CDJ46258.1 - 0.14 11.8 32.7 0.068 12.8 29.9 1.7 2 0 0 2 2 2 0 Spt20 family Peptidase_S64 PF08192.11 CDJ46258.1 - 0.15 10.5 8.0 0.16 10.5 8.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 ALMT PF11744.8 CDJ46258.1 - 0.2 10.4 5.7 0.21 10.4 5.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Med26_C PF15693.5 CDJ46258.1 - 0.23 11.6 16.0 0.28 11.3 15.7 1.3 1 1 0 1 1 1 0 Mediator complex subunit 26 C-terminal Folate_carrier PF01770.18 CDJ46258.1 - 0.45 9.2 3.7 0.54 8.9 3.7 1.3 1 0 0 1 1 1 0 Reduced folate carrier DUF2828 PF11443.8 CDJ46258.1 - 0.45 8.5 9.9 0.45 8.5 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4647 PF15504.6 CDJ46258.1 - 0.52 9.4 14.9 0.63 9.1 14.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF3347 PF11827.8 CDJ46258.1 - 0.61 10.3 18.8 0.85 9.8 18.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Ndc1_Nup PF09531.10 CDJ46258.1 - 0.63 8.7 11.1 0.73 8.5 11.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Membralin PF09746.9 CDJ46258.1 - 0.71 8.8 5.2 0.74 8.8 5.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4770 PF15994.5 CDJ46258.1 - 0.71 10.1 12.2 1.1 9.5 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) MDM10 PF12519.8 CDJ46258.1 - 0.72 8.7 7.5 0.72 8.6 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 eIF-3_zeta PF05091.12 CDJ46258.1 - 0.73 8.7 16.7 1.1 8.1 16.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF966 PF06136.13 CDJ46258.1 - 0.74 9.5 10.4 0.87 9.2 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) BAF1_ABF1 PF04684.13 CDJ46258.1 - 0.8 8.7 16.8 1.1 8.2 16.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Miga PF10265.9 CDJ46258.1 - 1.1 8.2 10.3 1.2 8.0 10.3 1.0 1 0 0 1 1 1 0 Mitoguardin TFB6 PF17110.5 CDJ46258.1 - 1.3 8.7 8.0 2.2 8.0 8.0 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH MMU163 PF17119.5 CDJ46258.1 - 1.4 8.0 5.6 2.5 7.2 5.6 1.4 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Cellulose_synt PF03552.14 CDJ46258.1 - 1.6 7.1 3.4 1.8 7.0 3.4 1.1 1 0 0 1 1 1 0 Cellulose synthase Nitroreductase PF00881.24 CDJ46258.1 - 1.9 8.5 14.7 1.6 8.7 13.2 1.6 1 1 1 2 2 2 0 Nitroreductase family V_ATPase_I PF01496.19 CDJ46258.1 - 4 5.2 14.5 2.9 5.7 13.6 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Activator_LAG-3 PF11498.8 CDJ46258.1 - 4.2 6.2 35.2 5.7 5.8 35.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4834 PF16118.5 CDJ46258.1 - 5.7 8.0 20.8 0.34 11.9 14.4 2.1 2 1 1 3 3 2 0 Domain of unknown function (DUF4834) GREB1 PF15782.5 CDJ46258.1 - 7.5 3.5 12.1 8.3 3.4 12.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AUX_IAA PF02309.16 CDJ46258.1 - 7.8 6.3 11.3 10 5.9 11.3 1.2 1 0 0 1 1 1 0 AUX/IAA family MDM31_MDM32 PF08118.11 CDJ46258.1 - 8.2 5.0 10.3 14 4.2 10.3 1.4 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins EMC3_TMCO1 PF01956.16 CDJ46258.1 - 8.7 6.1 11.5 12 5.6 11.5 1.4 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Pex14_N PF04695.13 CDJ46258.1 - 9.4 6.9 22.6 6.2 7.5 21.1 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 CDJ46259.1 - 1.5 8.6 34.7 1.6 8.5 34.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GPCR_chapero_1 PF11904.8 CDJ46259.1 - 3.5 7.0 26.5 3.9 6.8 26.5 1.0 1 0 0 1 1 1 0 GPCR-chaperone CDC45 PF02724.14 CDJ46259.1 - 3.5 5.8 28.6 3.7 5.7 28.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 CDJ46259.1 - 4.9 7.4 35.7 5.5 7.3 35.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 V_ATPase_I PF01496.19 CDJ46259.1 - 6.6 4.5 36.8 7.3 4.4 36.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPR3 PF03666.13 CDJ46259.1 - 6.8 5.4 29.8 7.2 5.3 29.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Raftlin PF15250.6 CDJ46259.1 - 8.4 5.0 27.4 8.7 5.0 27.4 1.0 1 0 0 1 1 1 0 Raftlin SR-25 PF10500.9 CDJ46260.1 - 0.0013 18.4 27.4 0.0013 18.4 27.4 3.0 1 1 2 3 3 3 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ46260.1 - 0.2 12.0 12.9 0.46 10.8 11.7 2.2 1 1 0 1 1 1 0 Early growth response N-terminal domain BASP1 PF05466.12 CDJ46261.1 - 0.2 11.6 38.8 0.25 11.3 38.8 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Med15 PF09606.10 CDJ46261.1 - 0.35 9.5 14.0 0.43 9.2 14.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Apt1 PF10351.9 CDJ46261.1 - 0.37 9.6 12.4 0.47 9.3 12.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.15 CDJ46261.1 - 0.51 9.9 15.7 0.96 8.9 15.7 1.4 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist BUD22 PF09073.10 CDJ46261.1 - 0.88 8.9 21.6 1.3 8.3 21.6 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 CDJ46261.1 - 1.1 9.2 21.9 1.5 8.7 21.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ46263.1 - 0.0022 16.8 1.1 0.0024 16.7 1.1 1.2 1 0 0 1 1 1 1 Presenilin Med15 PF09606.10 CDJ46263.1 - 0.0066 15.2 14.3 0.0092 14.7 14.3 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal CCDC53 PF10152.9 CDJ46263.1 - 0.0068 16.8 0.5 0.0068 16.8 0.5 1.9 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex DUF2828 PF11443.8 CDJ46263.1 - 0.0095 14.1 0.8 0.011 13.8 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) SpoIIP PF07454.11 CDJ46263.1 - 0.0099 15.4 1.5 0.0099 15.4 1.5 1.5 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) Pex14_N PF04695.13 CDJ46263.1 - 0.011 16.4 6.8 0.011 16.4 6.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.12 CDJ46263.1 - 0.011 14.7 5.8 0.015 14.3 5.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3408 PF11888.8 CDJ46263.1 - 0.024 14.8 3.2 0.024 14.8 3.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Serinc PF03348.15 CDJ46263.1 - 0.074 12.0 0.5 0.09 11.7 0.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Connexin PF00029.19 CDJ46263.1 - 0.085 12.6 1.6 0.13 12.0 1.6 1.3 1 0 0 1 1 1 0 Connexin SpoIIE PF07228.12 CDJ46263.1 - 0.11 12.5 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) CLN3 PF02487.17 CDJ46263.1 - 0.21 10.6 0.2 0.28 10.2 0.2 1.2 1 0 0 1 1 1 0 CLN3 protein UPF0560 PF10577.9 CDJ46263.1 - 0.77 8.2 11.5 1.1 7.7 11.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Neur_chan_memb PF02932.16 CDJ46263.1 - 0.85 9.6 2.8 0.31 11.0 0.7 1.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 CDJ46263.1 - 0.88 9.5 3.0 0.27 11.1 0.3 1.6 2 0 0 2 2 2 0 N-glycosylation protein AIF_C PF14721.6 CDJ46263.1 - 0.94 9.8 6.7 0.2 12.0 2.9 1.7 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Conotoxin PF02950.17 CDJ46263.1 - 1.6 9.8 3.7 6.9 7.8 2.0 2.3 2 0 0 2 2 2 0 Conotoxin DUF5327 PF17261.2 CDJ46263.1 - 2.2 9.1 14.6 12 6.7 12.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF3464 PF11947.8 CDJ46263.1 - 2.3 7.9 8.9 0.24 11.1 3.1 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF2967 PF11179.8 CDJ46263.1 - 2.6 6.0 12.8 4.2 5.3 12.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF1980 PF09323.10 CDJ46263.1 - 2.9 7.8 5.1 0.52 10.2 1.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Spt20 PF12090.8 CDJ46263.1 - 6.2 6.4 32.6 3.3 7.3 29.4 1.8 2 0 0 2 2 2 0 Spt20 family V_ATPase_I PF01496.19 CDJ46263.1 - 6.3 4.6 7.1 8.7 4.1 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Coilin_N PF15862.5 CDJ46263.1 - 9.8 6.0 16.8 1.4 8.7 11.2 2.0 2 0 0 2 2 2 0 Coilin N-terminus CobT PF06213.12 CDJ46264.1 - 0.0086 15.5 18.5 0.0088 15.5 18.5 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT FYDLN_acid PF09538.10 CDJ46264.1 - 0.015 15.9 5.1 0.016 15.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Tmem26 PF09772.9 CDJ46264.1 - 0.018 14.4 7.5 0.021 14.2 7.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 26 DUF2370 PF10176.9 CDJ46264.1 - 0.018 14.7 2.6 0.02 14.5 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4366 PF14283.6 CDJ46264.1 - 0.031 14.3 5.6 0.033 14.2 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SpoIIP PF07454.11 CDJ46264.1 - 0.038 13.5 13.2 0.038 13.5 13.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Afi1 PF07792.12 CDJ46264.1 - 0.052 14.0 12.7 0.064 13.7 12.7 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CPSF100_C PF13299.6 CDJ46264.1 - 0.074 13.2 11.3 0.079 13.1 11.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MPM1 PF17234.2 CDJ46264.1 - 0.1 12.9 12.8 0.11 12.8 12.8 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Presenilin PF01080.17 CDJ46264.1 - 0.11 11.2 14.0 0.11 11.3 14.0 1.1 1 0 0 1 1 1 0 Presenilin TRAP_alpha PF03896.16 CDJ46264.1 - 0.12 11.5 5.3 0.12 11.5 5.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Fungal_trans_2 PF11951.8 CDJ46264.1 - 0.13 11.1 9.8 0.15 10.9 9.8 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain EIIBC-GUT_N PF03612.14 CDJ46264.1 - 0.13 12.0 10.1 0.16 11.7 10.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CDC45 PF02724.14 CDJ46264.1 - 0.18 10.0 10.3 0.17 10.1 10.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 CDJ46264.1 - 0.19 11.5 10.9 0.2 11.4 10.9 1.1 1 0 0 1 1 1 0 Connexin Rxt3 PF08642.10 CDJ46264.1 - 0.2 12.4 5.3 0.23 12.2 5.3 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Peroxin-13_N PF04088.13 CDJ46264.1 - 0.2 11.9 6.6 0.25 11.6 6.6 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF913 PF06025.12 CDJ46264.1 - 0.21 10.5 6.4 0.22 10.4 6.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 CDJ46264.1 - 0.23 10.2 10.3 0.23 10.2 10.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Eapp_C PF10238.9 CDJ46264.1 - 0.27 11.3 14.2 0.33 11.0 14.2 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Lin-8 PF03353.15 CDJ46264.1 - 0.34 10.4 18.1 0.36 10.3 18.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FemAB PF02388.16 CDJ46264.1 - 0.35 9.7 10.9 0.38 9.6 10.9 1.0 1 0 0 1 1 1 0 FemAB family DUF4484 PF14831.6 CDJ46264.1 - 0.39 10.7 10.5 0.4 10.7 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) CCDC53 PF10152.9 CDJ46264.1 - 0.41 11.1 12.4 0.54 10.7 12.4 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF5523 PF17661.1 CDJ46264.1 - 0.47 10.1 18.3 0.61 9.7 18.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) HCO3_cotransp PF00955.21 CDJ46264.1 - 0.48 9.2 4.5 0.52 9.1 4.5 1.0 1 0 0 1 1 1 0 HCO3- transporter family PPL5 PF18168.1 CDJ46264.1 - 0.48 9.7 8.5 0.51 9.6 8.5 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Velvet PF11754.8 CDJ46264.1 - 0.6 10.0 12.6 0.7 9.8 12.6 1.0 1 0 0 1 1 1 0 Velvet factor Sec62 PF03839.16 CDJ46264.1 - 0.62 9.5 9.4 0.64 9.5 9.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DDHD PF02862.17 CDJ46264.1 - 0.8 9.8 12.5 0.9 9.7 12.5 1.1 1 0 0 1 1 1 0 DDHD domain Kei1 PF08552.11 CDJ46264.1 - 0.83 9.5 6.7 0.85 9.5 6.7 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Gti1_Pac2 PF09729.9 CDJ46264.1 - 0.84 9.7 9.8 0.9 9.6 9.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Zip PF02535.22 CDJ46264.1 - 0.9 8.7 7.5 0.95 8.6 7.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3395 PF11875.8 CDJ46264.1 - 0.92 9.4 18.2 1 9.3 18.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) RR_TM4-6 PF06459.12 CDJ46264.1 - 0.94 9.2 15.5 1.2 8.9 15.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4770 PF15994.5 CDJ46264.1 - 0.95 9.7 12.8 1 9.6 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) CLN3 PF02487.17 CDJ46264.1 - 0.96 8.4 10.6 0.89 8.5 10.6 1.0 1 0 0 1 1 1 0 CLN3 protein MDM10 PF12519.8 CDJ46264.1 - 0.98 8.2 10.1 0.97 8.2 10.1 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 EPL1 PF10513.9 CDJ46264.1 - 0.98 9.8 14.4 1.2 9.5 14.4 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF4638 PF15472.6 CDJ46264.1 - 1 9.1 12.5 1.2 8.9 12.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) SLC12 PF03522.15 CDJ46264.1 - 1 8.3 13.1 1 8.3 13.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Consortin_C PF15281.6 CDJ46264.1 - 1.1 9.3 5.9 1.4 8.9 5.9 1.2 1 0 0 1 1 1 0 Consortin C-terminus PIP5K PF01504.18 CDJ46264.1 - 1.2 8.3 11.8 1.6 7.9 11.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase THOC2_N PF16134.5 CDJ46264.1 - 1.5 7.4 10.8 1.7 7.2 10.8 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus HSNSD PF12062.8 CDJ46264.1 - 1.6 7.3 7.4 1.7 7.2 7.4 1.0 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase Peptidase_S64 PF08192.11 CDJ46264.1 - 1.9 6.9 11.2 1.9 6.9 11.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 Mem_trans PF03547.18 CDJ46264.1 - 2.1 6.6 7.0 2.1 6.6 7.0 1.0 1 0 0 1 1 1 0 Membrane transport protein Cellulose_synt PF03552.14 CDJ46264.1 - 2.2 6.7 7.5 2.5 6.5 7.5 1.0 1 0 0 1 1 1 0 Cellulose synthase Folate_carrier PF01770.18 CDJ46264.1 - 2.3 6.9 8.0 2.3 6.9 8.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier Band_3_cyto PF07565.13 CDJ46264.1 - 2.3 8.0 12.9 2.4 7.9 12.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Scs3p PF10261.9 CDJ46264.1 - 2.3 7.6 4.7 2.4 7.6 4.7 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Pet20 PF08692.10 CDJ46264.1 - 2.4 8.9 6.0 2.9 8.6 6.0 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Peptidase_U57 PF05582.12 CDJ46264.1 - 2.5 7.3 10.5 2.7 7.2 10.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 ALMT PF11744.8 CDJ46264.1 - 2.5 6.8 10.9 2.3 6.9 10.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3464 PF11947.8 CDJ46264.1 - 2.6 7.8 14.2 3.7 7.3 14.2 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FAM60A PF15396.6 CDJ46264.1 - 2.9 7.9 12.3 3.9 7.4 12.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A MDM31_MDM32 PF08118.11 CDJ46264.1 - 3 6.4 11.0 3.8 6.1 11.0 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins GNAT_acetyltr_2 PF13718.6 CDJ46264.1 - 3 7.2 10.8 3.4 7.0 10.8 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 EOS1 PF12326.8 CDJ46264.1 - 3 7.7 6.5 3.7 7.4 6.5 1.2 1 0 0 1 1 1 0 N-glycosylation protein Tim54 PF11711.8 CDJ46264.1 - 3.1 6.5 14.8 3.9 6.2 14.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2126 PF09899.9 CDJ46264.1 - 3.2 5.7 9.1 3.3 5.7 9.1 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) TERB2 PF15101.6 CDJ46264.1 - 3.5 7.6 19.6 4 7.4 19.6 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SID-1_RNA_chan PF13965.6 CDJ46264.1 - 3.6 5.9 8.1 3.7 5.9 8.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PepSY_TM PF03929.16 CDJ46264.1 - 3.9 7.1 5.6 3.7 7.1 5.6 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Peptidase_S49_N PF08496.10 CDJ46264.1 - 4 7.5 13.7 5.8 7.0 13.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Paramyxo_ncap PF00973.19 CDJ46264.1 - 4.1 6.2 9.1 4.1 6.2 9.1 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Hid1 PF12722.7 CDJ46264.1 - 4.9 5.2 12.5 4.9 5.2 12.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YABBY PF04690.13 CDJ46264.1 - 5.3 7.6 10.9 5.4 7.6 10.9 1.2 1 0 0 1 1 1 0 YABBY protein DUF1980 PF09323.10 CDJ46264.1 - 5.6 6.8 10.3 6 6.8 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Ctr PF04145.15 CDJ46264.1 - 5.7 7.5 8.1 6 7.5 8.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Membralin PF09746.9 CDJ46264.1 - 6.2 5.8 9.0 5.8 5.8 9.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein AIF_C PF14721.6 CDJ46264.1 - 6.4 7.1 13.2 9.5 6.6 13.2 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FHIPEP PF00771.20 CDJ46264.1 - 6.7 5.0 10.7 6.8 5.0 10.7 1.1 1 0 0 1 1 1 0 FHIPEP family TFIIA PF03153.13 CDJ46264.1 - 7.2 6.5 35.1 8.5 6.2 35.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dynamin_N PF00350.23 CDJ46264.1 - 7.3 6.6 8.7 7.9 6.5 8.7 1.1 1 0 0 1 1 1 0 Dynamin family Orf78 PF06024.12 CDJ46264.1 - 7.4 6.9 11.7 16 5.8 11.7 1.6 1 1 0 1 1 1 0 Orf78 (ac78) Ureide_permease PF07168.11 CDJ46264.1 - 7.7 5.2 7.8 9 4.9 7.8 1.1 1 0 0 1 1 1 0 Ureide permease Neur_chan_memb PF02932.16 CDJ46264.1 - 8.3 6.4 11.7 8.6 6.3 11.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.6 CDJ46264.1 - 8.6 4.1 37.2 9.6 4.0 37.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Nucleoside_tran PF01733.18 CDJ46264.1 - 8.8 5.6 7.3 9 5.6 7.3 1.1 1 0 0 1 1 1 0 Nucleoside transporter O-antigen_lig PF13425.6 CDJ46264.1 - 9.4 4.9 9.0 11 4.7 9.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ATP-synt_E PF05680.12 CDJ46264.1 - 9.5 6.6 16.4 17 5.9 16.4 1.4 1 0 0 1 1 1 0 ATP synthase E chain CSG2 PF16965.5 CDJ46264.1 - 9.6 5.0 9.3 11 4.9 9.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Suf PF05843.14 CDJ46264.1 - 9.9 6.0 16.9 13 5.7 16.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3c_N PF05470.12 CDJ46265.1 - 3.2e-104 349.4 29.1 2.1e-70 237.7 4.3 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CDJ46265.1 - 3.3e-12 46.8 0.1 4.1e-11 43.3 0.0 2.9 3 1 0 3 3 3 1 PCI domain RAP1 PF07218.11 CDJ46265.1 - 1.2 7.3 13.7 2.1 6.6 13.7 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Fmp27 PF10344.9 CDJ46265.1 - 1.2 7.1 10.1 2.2 6.3 10.1 1.3 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF2722 PF10846.8 CDJ46266.1 - 0.00035 19.7 4.3 0.00035 19.7 4.3 8.8 6 2 0 7 7 7 4 Protein of unknown function (DUF2722) Shadoo PF14999.6 CDJ46266.1 - 0.0018 18.4 0.9 0.0018 18.4 0.9 7.6 5 2 1 7 7 7 2 Shadow of prion protein, neuroprotective Cyt_bd_oxida_II PF02322.15 CDJ46266.1 - 1.1 8.5 4.7 0.58 9.5 0.1 2.4 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II DUF4045 PF13254.6 CDJ46267.1 - 0.43 10.2 27.9 0.49 10.0 27.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SPX PF03105.19 CDJ46267.1 - 0.72 9.7 27.6 0.85 9.5 27.6 1.0 1 0 0 1 1 1 0 SPX domain Membralin PF09746.9 CDJ46267.1 - 0.8 8.7 16.6 0.96 8.4 16.6 1.3 1 0 0 1 1 1 0 Tumour-associated protein Caldesmon PF02029.15 CDJ46267.1 - 0.86 8.3 37.0 1.1 8.0 37.0 1.0 1 0 0 1 1 1 0 Caldesmon PAT1 PF09770.9 CDJ46267.1 - 1.1 7.4 55.6 1.3 7.2 55.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.9 CDJ46267.1 - 1.1 8.0 19.5 1.3 7.8 19.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 CDJ46267.1 - 1.2 7.4 26.9 1.4 7.1 26.9 1.1 1 0 0 1 1 1 0 CDC45-like protein WTX PF09422.10 CDJ46267.1 - 1.2 8.1 21.8 1.6 7.7 21.8 1.2 1 0 0 1 1 1 0 WTX protein CAC1F_C PF16885.5 CDJ46267.1 - 1.4 8.6 22.9 1.7 8.2 22.9 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term VIR_N PF15912.5 CDJ46267.1 - 1.6 8.3 27.1 2 8.0 27.1 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal CCSAP PF15748.5 CDJ46267.1 - 1.6 8.9 39.0 2.3 8.3 39.0 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Macoilin PF09726.9 CDJ46267.1 - 1.9 7.0 26.1 2.4 6.6 26.1 1.2 1 0 0 1 1 1 0 Macoilin family SARG PF15385.6 CDJ46267.1 - 2.8 7.0 37.6 3.4 6.8 37.6 1.0 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Bul1_N PF04425.12 CDJ46267.1 - 3.1 6.5 21.4 4 6.1 21.4 1.4 1 0 0 1 1 1 0 Bul1 N terminus SID-1_RNA_chan PF13965.6 CDJ46267.1 - 7.9 4.8 14.4 10 4.4 14.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Dapper PF15268.6 CDJ46267.1 - 9.1 5.0 39.4 10 4.8 39.4 1.0 1 0 0 1 1 1 0 Dapper Peptidase_S64 PF08192.11 CDJ46267.1 - 9.6 4.6 23.7 13 4.1 23.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 SLC12 PF03522.15 CDJ46267.1 - 9.6 5.1 36.9 12 4.8 36.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GDA1_CD39 PF01150.17 CDJ46268.1 - 1.9e-09 36.7 0.4 1.2e-06 27.4 0.2 3.3 2 1 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family AAA_11 PF13086.6 CDJ46268.1 - 0.0027 17.5 12.7 0.0027 17.5 12.7 3.4 3 0 0 3 3 3 1 AAA domain SAGA-Tad1 PF12767.7 CDJ46268.1 - 0.0035 17.1 2.2 0.0035 17.1 2.2 3.1 3 0 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit Pex14_N PF04695.13 CDJ46268.1 - 0.017 15.8 21.4 0.017 15.8 21.4 4.1 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2721 PF11026.8 CDJ46268.1 - 0.071 13.0 1.9 5.3 6.9 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Endostatin PF06482.11 CDJ46268.1 - 0.33 10.4 20.2 0.065 12.7 8.4 2.7 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin RCR PF12273.8 CDJ46268.1 - 0.52 11.0 17.0 8 7.2 0.4 2.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red UPF0261 PF06792.11 CDJ46268.1 - 0.6 9.0 11.7 3 6.7 3.1 3.4 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0261) SID-1_RNA_chan PF13965.6 CDJ46268.1 - 1.7 7.0 4.2 1.2 7.5 0.9 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Velvet PF11754.8 CDJ46268.1 - 9.6 6.1 30.2 0.6 10.0 13.3 2.8 3 0 0 3 3 3 0 Velvet factor Pex14_N PF04695.13 CDJ46269.1 - 0.001 19.7 28.1 0.0012 19.5 28.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DotU PF09850.9 CDJ46269.1 - 0.044 13.5 8.4 0.056 13.2 8.4 1.1 1 0 0 1 1 1 0 Type VI secretion system protein DotU ABC2_membrane_2 PF12679.7 CDJ46269.1 - 0.2 10.9 5.5 0.27 10.5 5.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein BAF1_ABF1 PF04684.13 CDJ46269.1 - 0.21 10.6 19.0 0.25 10.4 19.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FAM76 PF16046.5 CDJ46269.1 - 0.29 10.5 16.5 0.32 10.3 16.5 1.0 1 0 0 1 1 1 0 FAM76 protein Shadoo PF14999.6 CDJ46269.1 - 0.36 10.9 7.6 0.43 10.7 7.6 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF4366 PF14283.6 CDJ46269.1 - 0.64 10.1 9.8 0.81 9.7 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3292 PF11696.8 CDJ46269.1 - 1.3 7.3 13.2 1.5 7.1 13.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) PPL5 PF18168.1 CDJ46269.1 - 1.3 8.3 11.9 1.4 8.1 11.9 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Velvet PF11754.8 CDJ46269.1 - 1.6 8.6 17.2 1.6 8.6 17.2 1.1 1 0 0 1 1 1 0 Velvet factor Paf1 PF03985.13 CDJ46269.1 - 1.8 7.5 18.1 1.9 7.4 18.1 1.0 1 0 0 1 1 1 0 Paf1 PTPRCAP PF15713.5 CDJ46269.1 - 2.1 8.6 19.2 2.6 8.3 19.2 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated ATP11 PF06644.11 CDJ46269.1 - 2.1 8.0 19.9 2.5 7.8 19.9 1.1 1 0 0 1 1 1 0 ATP11 protein CTU2 PF10288.9 CDJ46269.1 - 2.7 8.3 14.4 3.6 7.8 14.4 1.3 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 NST1 PF13945.6 CDJ46269.1 - 2.8 8.0 26.1 3.3 7.8 26.1 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4045 PF13254.6 CDJ46269.1 - 3.1 7.3 19.9 3.5 7.2 19.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SpoIIP PF07454.11 CDJ46269.1 - 3.3 7.1 18.1 3.4 7.1 18.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Lin-8 PF03353.15 CDJ46269.1 - 3.4 7.1 25.3 3.9 6.9 25.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Peptidase_S49_N PF08496.10 CDJ46269.1 - 3.4 7.7 13.1 3.8 7.6 13.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal VIT1 PF01988.19 CDJ46269.1 - 3.5 7.4 9.0 4.3 7.1 9.0 1.1 1 0 0 1 1 1 0 VIT family Tim54 PF11711.8 CDJ46269.1 - 3.8 6.2 18.2 4.2 6.0 18.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Methyltransf_32 PF13679.6 CDJ46269.1 - 4.1 7.4 14.2 5.1 7.1 14.2 1.2 1 0 0 1 1 1 0 Methyltransferase domain NPR3 PF03666.13 CDJ46269.1 - 4.5 6.0 16.0 4.6 5.9 16.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 API5 PF05918.11 CDJ46269.1 - 4.8 5.9 21.6 5.4 5.7 21.6 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Connexin PF00029.19 CDJ46269.1 - 5 6.8 13.3 5.2 6.8 13.3 1.1 1 0 0 1 1 1 0 Connexin MecA PF05389.12 CDJ46269.1 - 5.5 6.6 12.9 7.7 6.1 12.9 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Band_3_cyto PF07565.13 CDJ46269.1 - 5.7 6.7 16.6 6.6 6.5 16.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Membralin PF09746.9 CDJ46269.1 - 6.2 5.8 12.7 6.1 5.8 12.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein Presenilin PF01080.17 CDJ46269.1 - 6.2 5.5 24.8 6.3 5.4 24.8 1.0 1 0 0 1 1 1 0 Presenilin DUF5427 PF10310.9 CDJ46269.1 - 6.6 5.6 24.0 7.7 5.3 24.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Tuberin PF03542.16 CDJ46269.1 - 7.4 5.6 9.1 7.7 5.5 9.1 1.0 1 0 0 1 1 1 0 Tuberin DUF4746 PF15928.5 CDJ46269.1 - 7.5 5.9 12.9 8.4 5.7 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Mcm10 PF09332.11 CDJ46269.1 - 7.5 5.9 21.5 8.8 5.6 21.5 1.0 1 0 0 1 1 1 0 Mcm10 replication factor Mitofilin PF09731.9 CDJ46269.1 - 7.5 5.3 24.9 9.5 4.9 24.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC45 PF02724.14 CDJ46269.1 - 7.8 4.7 13.8 8.1 4.6 13.8 1.0 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 CDJ46269.1 - 9.1 6.1 48.4 11 5.9 48.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDRGK PF09756.9 CDJ46269.1 - 9.5 5.8 23.0 12 5.5 23.0 1.1 1 0 0 1 1 1 0 DDRGK domain CTP_synth_N PF06418.14 CDJ46270.1 - 9.6e-108 359.5 0.0 2.6e-62 210.6 0.1 2.1 2 0 0 2 2 2 2 CTP synthase N-terminus GATase PF00117.28 CDJ46270.1 - 2.9e-44 151.1 0.0 5.1e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CDJ46270.1 - 0.0041 16.9 0.2 0.025 14.3 0.2 2.1 1 1 0 1 1 1 1 Peptidase C26 MeaB PF03308.16 CDJ46270.1 - 0.029 13.3 0.4 0.029 13.3 0.4 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 CDJ46270.1 - 0.068 13.2 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MGC-24 PF05283.11 CDJ46271.1 - 3.3 8.2 16.4 5.7 7.4 16.4 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TctA PF01970.16 CDJ46272.1 - 0.013 14.2 2.3 0.023 13.4 2.3 1.4 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family DUF3040 PF11239.8 CDJ46272.1 - 0.12 12.6 0.2 0.12 12.6 0.2 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3040) PTR2 PF00854.21 CDJ46272.1 - 0.16 10.7 4.0 1.7 7.4 0.5 2.5 1 1 1 2 2 2 0 POT family DUF2207 PF09972.9 CDJ46272.1 - 5.8 5.6 5.3 21 3.7 0.7 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) RskA PF10099.9 CDJ46274.1 - 0.015 15.6 61.7 0.026 14.8 25.3 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA AAA_23 PF13476.6 CDJ46274.1 - 0.13 12.8 17.3 1.5 9.3 12.3 2.1 2 0 0 2 2 2 0 AAA domain BSP_II PF05432.11 CDJ46274.1 - 0.55 9.9 29.5 1.5 8.4 29.5 1.6 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) DivIC PF04977.15 CDJ46274.1 - 2.2 8.1 33.6 1.7 8.5 17.9 2.4 2 0 0 2 2 2 0 Septum formation initiator SurA_N_2 PF13623.6 CDJ46274.1 - 2.6 7.9 27.3 0.69 9.8 4.8 2.4 2 0 0 2 2 2 0 SurA N-terminal domain EphA2_TM PF14575.6 CDJ46274.1 - 3.6 8.5 12.1 2.1 9.3 0.4 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Csa1 PF06023.12 CDJ46274.1 - 3.6 6.8 9.5 0.11 11.8 2.6 1.7 1 1 1 2 2 2 0 CRISPR-associated exonuclease Csa1 SR-25 PF10500.9 CDJ46275.1 - 0.98 9.0 7.7 0.45 10.1 3.7 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.13 CDJ46276.1 - 0.037 13.1 24.3 0.045 12.8 24.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Shadoo PF14999.6 CDJ46276.1 - 0.11 12.6 3.5 0.14 12.2 3.5 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF3347 PF11827.8 CDJ46276.1 - 1.4 9.1 26.0 2 8.6 26.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Peroxin-13_N PF04088.13 CDJ46276.1 - 1.4 9.1 16.3 2.8 8.2 0.6 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region PBP1_TM PF14812.6 CDJ46276.1 - 2.4 8.6 12.6 14 6.1 7.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Afi1 PF07792.12 CDJ46276.1 - 3.2 8.2 23.2 4.5 7.8 15.3 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SelP_N PF04592.14 CDJ46276.1 - 6.6 6.1 33.7 4.7 6.5 24.0 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Cir_N PF10197.9 CDJ46277.1 - 4e-12 46.1 13.1 4e-12 46.1 13.1 3.6 3 2 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Ribosomal_S22 PF08136.11 CDJ46277.1 - 0.043 14.2 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 30S ribosomal protein subunit S22 family HSP70 PF00012.20 CDJ46277.1 - 0.88 7.7 10.0 1.1 7.4 10.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Slu7 PF11708.8 CDJ46277.1 - 6.5 6.4 15.4 3.4 7.3 10.4 2.5 2 1 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor DEAD PF00270.29 CDJ46278.1 - 2.2e-27 96.0 0.0 4.3e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ46278.1 - 7.6e-18 64.9 0.0 1.8e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2017 PF09438.10 CDJ46278.1 - 0.035 14.0 0.5 0.035 14.0 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2017) ResIII PF04851.15 CDJ46278.1 - 0.11 12.5 0.0 5.4 7.0 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit EF-hand_7 PF13499.6 CDJ46279.1 - 2.6e-11 43.8 0.1 0.0001 22.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ46279.1 - 6.2e-11 41.3 0.0 0.00017 21.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDJ46279.1 - 1.2e-09 37.0 0.0 0.0017 17.8 0.0 2.7 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 CDJ46279.1 - 8.9e-07 29.1 0.1 0.084 13.2 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ46279.1 - 0.00014 21.6 0.0 0.029 14.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ46279.1 - 0.00077 18.9 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 EF hand DUF2703 PF10865.8 CDJ46279.1 - 0.11 12.6 0.1 8.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) BRCT_2 PF16589.5 CDJ46280.1 - 0.0027 18.1 0.0 0.0062 16.9 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Voltage_CLC PF00654.20 CDJ46281.1 - 1.9e-48 165.6 33.4 1.3e-24 87.1 10.4 3.7 4 0 0 4 4 4 3 Voltage gated chloride channel RR_TM4-6 PF06459.12 CDJ46282.1 - 6.7 6.4 9.6 14 5.4 9.6 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 CDJ46282.1 - 9.2 4.3 9.1 11 3.9 9.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IBR PF01485.21 CDJ46283.1 - 2.8e-18 65.9 27.8 6.4e-10 39.1 4.3 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain PPDK_N PF01326.19 CDJ46284.1 - 7.4e-14 51.7 0.0 1.4e-12 47.5 0.0 3.2 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF4355 PF14265.6 CDJ46284.1 - 0.018 15.3 0.4 0.018 15.3 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) RAP1 PF07218.11 CDJ46286.1 - 5.3 5.2 10.0 6.8 4.8 10.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S49_N PF08496.10 CDJ46288.1 - 0.36 10.9 6.3 0.43 10.6 6.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.16 CDJ46288.1 - 0.39 10.7 10.7 0.48 10.4 10.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SelP_N PF04592.14 CDJ46288.1 - 0.48 9.8 20.0 0.55 9.6 20.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ribosomal_60s PF00428.19 CDJ46288.1 - 0.64 10.7 9.4 0.93 10.1 9.4 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein MMR1 PF08505.10 CDJ46288.1 - 1.3 9.2 13.1 1.6 9.0 13.1 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 CDJ46288.1 - 2.5 8.0 34.3 3 7.7 34.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ46288.1 - 7.9 5.1 12.0 9.2 4.9 12.0 1.1 1 0 0 1 1 1 0 Presenilin NRIP1_repr_3 PF15689.5 CDJ46290.1 - 0.56 10.5 4.2 0.26 11.6 0.9 2.3 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 Tim54 PF11711.8 CDJ46291.1 - 0.00018 20.4 5.6 0.00018 20.4 5.6 2.1 1 1 1 2 2 1 1 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 CDJ46291.1 - 0.0014 17.4 23.3 0.0014 17.4 23.3 2.0 2 0 0 2 2 2 1 Presenilin Trehalose_PPase PF02358.16 CDJ46291.1 - 0.0032 16.7 0.0 0.0032 16.7 0.0 2.3 1 1 1 2 2 1 1 Trehalose-phosphatase Caldesmon PF02029.15 CDJ46291.1 - 0.015 14.1 24.1 0.019 13.8 24.1 1.2 1 0 0 1 1 1 0 Caldesmon CDK5_activator PF03261.15 CDJ46291.1 - 0.016 14.8 16.2 0.024 14.2 16.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein V_ATPase_I PF01496.19 CDJ46291.1 - 0.021 12.8 18.3 0.036 12.0 18.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mem_trans PF03547.18 CDJ46291.1 - 0.056 11.8 1.8 0.055 11.9 1.8 1.2 1 0 0 1 1 1 0 Membrane transport protein Sec62 PF03839.16 CDJ46291.1 - 0.95 8.9 20.8 0.23 10.9 17.7 1.6 2 0 0 2 2 2 0 Translocation protein Sec62 DAG_kinase_N PF14513.6 CDJ46291.1 - 1.5 9.0 22.8 0.29 11.3 17.4 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Raftlin PF15250.6 CDJ46291.1 - 1.5 7.5 23.9 0.041 12.6 15.2 2.0 2 0 0 2 2 2 0 Raftlin SLC12 PF03522.15 CDJ46291.1 - 2.8 6.9 29.6 0.27 10.2 25.2 1.4 2 0 0 2 2 2 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ46291.1 - 3.2 7.7 23.1 0.26 11.3 16.9 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SelP_N PF04592.14 CDJ46291.1 - 4.8 6.5 37.0 13 5.2 37.0 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF5585 PF17823.1 CDJ46291.1 - 5.3 5.9 25.4 7.8 5.3 25.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Membralin PF09746.9 CDJ46291.1 - 6.4 5.7 14.5 9.4 5.2 14.5 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF4569 PF15133.6 CDJ46291.1 - 7.1 6.3 31.6 0.56 9.9 26.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) DUF3807 PF12720.7 CDJ46291.1 - 8.2 6.7 40.6 2.6 8.3 32.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) SMYLE_N PF18615.1 CDJ46291.1 - 9.8 5.6 22.1 0.14 11.7 12.6 2.1 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Utp14 PF04615.13 CDJ46292.1 - 0.00029 19.6 2.7 0.00029 19.6 2.7 2.2 3 1 0 3 3 3 1 Utp14 protein MFS_2 PF13347.6 CDJ46292.1 - 0.026 13.1 0.0 0.059 11.9 0.0 1.5 1 0 0 1 1 1 0 MFS/sugar transport protein SIP PF04954.13 CDJ46292.1 - 0.084 13.4 0.3 0.084 13.4 0.3 3.8 3 0 0 3 3 3 0 Siderophore-interacting protein PolyA_pol PF01743.20 CDJ46293.1 - 9.5 6.7 9.7 9.9 6.6 9.7 1.0 1 0 0 1 1 1 0 Poly A polymerase head domain FRB_dom PF08771.11 CDJ46294.1 - 5e-14 52.5 0.0 5e-14 52.5 0.0 5.9 6 1 0 6 6 6 1 FKBP12-rapamycin binding domain SUIM_assoc PF16619.5 CDJ46294.1 - 0.0022 18.0 0.8 0.0022 18.0 0.8 28.5 20 7 6 26 26 26 3 Unstructured region C-term to UIM in Ataxin3 SelP_N PF04592.14 CDJ46295.1 - 0.16 11.4 13.9 0.2 11.0 13.9 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region UPF0560 PF10577.9 CDJ46295.1 - 0.18 10.2 16.3 0.22 10.0 16.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 NEMP PF10225.9 CDJ46295.1 - 1.3 8.7 3.2 1.6 8.3 3.2 1.1 1 0 0 1 1 1 0 NEMP family OmpH PF03938.14 CDJ46295.1 - 1.3 9.4 19.4 1.8 8.9 19.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Lin-8 PF03353.15 CDJ46295.1 - 1.3 8.5 15.2 1.5 8.3 15.2 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 CDJ46295.1 - 1.5 7.5 10.2 1.6 7.4 10.2 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ46295.1 - 1.6 8.6 33.4 2 8.3 33.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ46295.1 - 2 7.3 10.6 2.2 7.1 10.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ46295.1 - 2.6 8.1 8.7 3 7.8 8.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ46295.1 - 3.5 6.3 5.1 3.6 6.3 5.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SOG2 PF10428.9 CDJ46295.1 - 3.7 6.6 20.5 4.5 6.4 20.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein HemX PF04375.14 CDJ46295.1 - 3.9 6.7 23.9 4.9 6.3 23.9 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Baculo_PP31 PF05311.11 CDJ46295.1 - 5.1 6.5 9.7 6.1 6.3 9.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) EOS1 PF12326.8 CDJ46295.1 - 6.1 6.7 6.4 7.8 6.4 6.4 1.1 1 0 0 1 1 1 0 N-glycosylation protein Hid1 PF12722.7 CDJ46295.1 - 9.7 4.2 9.7 10 4.1 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Gly_transf_sug PF04488.15 CDJ46296.1 - 3.5e-09 37.2 0.0 1.3e-08 35.3 0.0 2.0 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif MecA PF05389.12 CDJ46296.1 - 0.3 10.7 20.8 0.27 10.9 4.2 3.3 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) PAT1 PF09770.9 CDJ46296.1 - 0.43 8.8 56.4 1.1 7.4 20.6 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.6 CDJ46296.1 - 1.8 6.3 69.2 1.8 6.4 34.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) FATC PF02260.20 CDJ46297.1 - 2.1e-13 49.8 0.0 3.5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 FATC domain RskA PF10099.9 CDJ46297.1 - 0.00083 19.7 22.3 0.0018 18.6 22.3 1.5 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF1772 PF08592.11 CDJ46297.1 - 0.012 15.9 3.0 0.029 14.7 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) SLATT_1 PF18181.1 CDJ46297.1 - 0.023 14.6 3.9 0.041 13.8 3.9 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 V_ATPase_I PF01496.19 CDJ46297.1 - 0.066 11.1 2.2 0.089 10.7 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ46297.1 - 0.096 12.7 17.2 0.12 12.4 17.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ46297.1 - 2.9 8.9 5.5 5.3 8.1 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) WRNPLPNID PF15017.6 CDJ46297.1 - 8.7 7.3 6.3 14 6.7 6.3 1.3 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box RskA PF10099.9 CDJ46298.1 - 0.00037 20.9 1.2 0.00089 19.6 1.2 1.6 1 1 0 1 1 1 1 Anti-sigma-K factor rskA PI3_PI4_kinase PF00454.27 CDJ46298.1 - 0.0057 16.5 0.0 0.0074 16.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Nkap_C PF06047.11 CDJ46298.1 - 0.038 14.1 1.5 0.057 13.5 1.5 1.2 1 0 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain Presenilin PF01080.17 CDJ46298.1 - 0.079 11.7 0.8 0.089 11.5 0.8 1.1 1 0 0 1 1 1 0 Presenilin Orf78 PF06024.12 CDJ46298.1 - 0.17 12.2 0.9 0.32 11.3 0.9 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Spt20 PF12090.8 CDJ46298.1 - 0.33 10.5 15.5 0.64 9.6 15.5 1.4 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ46298.1 - 0.38 10.3 16.1 2 8.0 7.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 CDJ46298.1 - 0.78 9.2 10.5 0.72 9.4 5.1 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Ribosomal_60s PF00428.19 CDJ46298.1 - 0.91 10.2 8.3 0.34 11.5 3.0 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4692 PF15763.5 CDJ46298.1 - 1.7 9.1 8.2 0.48 10.9 1.5 2.1 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DUF4834 PF16118.5 CDJ46298.1 - 2.2 9.3 5.2 0.64 11.0 2.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Filament_head PF04732.14 CDJ46299.1 - 1 10.2 46.7 3.3 8.6 5.6 4.8 4 0 0 4 4 4 0 Intermediate filament head (DNA binding) region UPF0160 PF03690.13 CDJ46300.1 - 1.9e-56 192.0 0.4 5.3e-27 95.3 0.0 3.7 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0160) DUF2722 PF10846.8 CDJ46300.1 - 6.3e-05 22.1 10.0 8e-05 21.8 10.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF5523 PF17661.1 CDJ46300.1 - 0.0026 17.5 6.4 0.0052 16.5 6.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5523) SpoIIP PF07454.11 CDJ46300.1 - 0.012 15.1 3.5 0.019 14.5 3.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CDJ46300.1 - 0.015 14.1 2.2 0.019 13.8 2.2 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ46300.1 - 0.021 13.6 3.5 0.034 12.9 3.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex14_N PF04695.13 CDJ46300.1 - 0.022 15.4 10.9 0.022 15.4 10.9 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MCU PF04678.13 CDJ46300.1 - 0.027 14.6 1.8 0.051 13.7 0.7 2.0 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CPSF100_C PF13299.6 CDJ46300.1 - 0.042 14.0 0.6 0.084 13.0 0.6 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hid1 PF12722.7 CDJ46300.1 - 0.11 10.6 1.5 0.13 10.4 1.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 CDJ46300.1 - 0.11 12.3 4.0 0.19 11.5 4.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4770 PF15994.5 CDJ46300.1 - 0.12 12.6 8.4 0.23 11.7 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) CCDC53 PF10152.9 CDJ46300.1 - 0.21 12.0 11.7 0.043 14.2 6.6 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex FAM176 PF14851.6 CDJ46300.1 - 0.29 10.8 2.8 0.54 9.9 2.8 1.4 1 0 0 1 1 1 0 FAM176 family Neur_chan_memb PF02932.16 CDJ46300.1 - 0.43 10.6 2.8 0.72 9.9 2.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0560 PF10577.9 CDJ46300.1 - 0.56 8.6 11.4 0.91 8.0 11.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 EIIBC-GUT_N PF03612.14 CDJ46300.1 - 0.77 9.5 7.0 1.6 8.5 7.0 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ORC_WH_C PF18137.1 CDJ46300.1 - 1.1 9.3 8.5 2.4 8.2 8.5 1.5 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF4834 PF16118.5 CDJ46300.1 - 1.3 10.0 8.7 2.6 9.1 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ46300.1 - 1.6 8.5 4.2 2.3 7.9 4.2 1.2 1 0 0 1 1 1 0 Connexin tRNA_synt_1c_R2 PF04557.15 CDJ46300.1 - 1.8 9.5 7.8 0.48 11.4 4.3 1.8 2 0 0 2 2 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Folate_carrier PF01770.18 CDJ46300.1 - 2.4 6.8 3.2 3.3 6.3 3.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier eIF-3_zeta PF05091.12 CDJ46300.1 - 2.9 6.8 12.6 4.6 6.1 12.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 CDJ46300.1 - 3.2 6.7 4.2 4.9 6.1 4.2 1.2 1 0 0 1 1 1 0 CLN3 protein TERB2 PF15101.6 CDJ46300.1 - 3.2 7.7 11.9 6.9 6.7 11.9 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF702 PF05142.12 CDJ46300.1 - 4.1 7.9 10.6 1.1 9.7 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF3464 PF11947.8 CDJ46300.1 - 4.7 6.9 10.4 10 5.8 10.4 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Sec62 PF03839.16 CDJ46300.1 - 6.5 6.2 7.7 10 5.6 7.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PAT1 PF09770.9 CDJ46300.1 - 8.1 4.6 20.2 0.28 9.4 13.0 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 LptF_LptG PF03739.14 CDJ46300.1 - 8.9 5.0 5.7 13 4.5 5.7 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG SR-25 PF10500.9 CDJ46301.1 - 0.00013 21.7 14.3 0.00015 21.5 14.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RSRP PF17069.5 CDJ46301.1 - 0.0038 16.9 13.0 0.0047 16.5 13.0 1.3 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 TFIIF_alpha PF05793.12 CDJ46301.1 - 0.41 9.2 10.7 0.46 9.0 10.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4228 PF14009.6 CDJ46301.1 - 0.65 10.4 10.0 0.89 9.9 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Hamartin PF04388.12 CDJ46301.1 - 1.8 7.1 15.2 2.2 6.9 15.2 1.0 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 CDJ46301.1 - 2.1 8.3 22.5 2.7 7.9 22.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 CDJ46301.1 - 4.8 5.3 5.5 4.7 5.4 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4207 PF13904.6 CDJ46302.1 - 0.12 12.1 22.9 0.14 11.8 22.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) MMR1 PF08505.10 CDJ46302.1 - 0.63 10.3 13.8 0.73 10.1 13.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TraA PF05513.11 CDJ46302.1 - 1.6 9.1 9.8 0.48 10.8 1.8 2.2 2 0 0 2 2 2 0 TraA Spt20 PF12090.8 CDJ46302.1 - 3.5 7.2 25.0 5.3 6.6 25.0 1.2 1 0 0 1 1 1 0 Spt20 family DUF4813 PF16072.5 CDJ46302.1 - 4.4 6.9 29.3 2.2 7.9 11.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) GREB1 PF15782.5 CDJ46302.1 - 8 3.4 13.7 8.6 3.3 13.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BAF1_ABF1 PF04684.13 CDJ46302.1 - 10 5.1 18.9 14 4.6 18.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Profilin PF00235.19 CDJ46303.1 - 4.2e-12 46.4 0.1 5.1e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 Profilin FA_desaturase PF00487.24 CDJ46304.1 - 0.042 13.7 2.1 14 5.4 2.9 3.5 3 0 0 3 3 3 0 Fatty acid desaturase SNARE PF05739.19 CDJ46305.1 - 3.8e-10 39.6 1.0 3.8e-10 39.6 1.0 1.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CDJ46305.1 - 2.3e-09 37.2 0.2 2.3e-09 37.2 0.2 1.8 2 0 0 2 2 2 1 Syntaxin TACC_C PF05010.14 CDJ46305.1 - 0.0083 15.9 4.2 0.01 15.6 4.2 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Helo_like_N PF17111.5 CDJ46305.1 - 0.012 15.0 0.2 0.014 14.7 0.2 1.1 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF846 PF05832.12 CDJ46305.1 - 0.012 15.6 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) VIT1 PF01988.19 CDJ46305.1 - 0.013 15.4 0.4 0.016 15.1 0.4 1.0 1 0 0 1 1 1 0 VIT family DUF4577 PF15145.6 CDJ46305.1 - 0.017 15.2 0.2 0.03 14.4 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4577) DUF1515 PF07439.11 CDJ46305.1 - 0.022 14.8 1.6 0.028 14.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Fusion_gly PF00523.18 CDJ46305.1 - 0.025 12.9 0.2 0.026 12.8 0.2 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 CRA PF06589.11 CDJ46305.1 - 0.027 14.6 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) MCPsignal PF00015.21 CDJ46305.1 - 0.028 14.3 1.0 0.034 14.0 0.2 1.5 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF5383 PF17355.2 CDJ46305.1 - 0.039 14.3 0.4 0.049 14.0 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DUF2207 PF09972.9 CDJ46305.1 - 0.045 12.5 0.2 0.043 12.6 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Z1 PF10593.9 CDJ46305.1 - 0.05 13.1 0.7 0.06 12.8 0.7 1.1 1 0 0 1 1 1 0 Z1 domain DUF16 PF01519.16 CDJ46305.1 - 0.055 14.0 2.8 0.07 13.6 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 T2SSF PF00482.23 CDJ46305.1 - 0.063 13.2 5.2 0.4 10.6 5.2 1.9 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F EMP24_GP25L PF01105.24 CDJ46305.1 - 0.22 11.4 3.6 0.35 10.8 3.6 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4231 PF14015.6 CDJ46305.1 - 0.22 12.0 3.7 0.66 10.5 2.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF1043 PF06295.12 CDJ46305.1 - 0.26 11.3 4.3 0.36 10.9 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2076 PF09849.9 CDJ46306.1 - 0.65 10.0 27.4 0.77 9.7 27.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SpoIIP PF07454.11 CDJ46306.1 - 1.1 8.7 16.4 1 8.7 16.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4471 PF14740.6 CDJ46306.1 - 1.2 8.3 11.5 1.1 8.4 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF5308 PF17233.2 CDJ46306.1 - 1.3 9.3 11.9 1.2 9.3 11.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) FAM150 PF15129.6 CDJ46306.1 - 1.3 9.2 14.9 1.8 8.7 14.9 1.2 1 0 0 1 1 1 0 FAM150 family PPL5 PF18168.1 CDJ46306.1 - 1.9 7.7 9.9 1.7 7.8 9.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 CDJ46306.1 - 2.3 6.9 19.2 2.1 7.0 19.2 1.1 1 0 0 1 1 1 0 Presenilin EPL1 PF10513.9 CDJ46306.1 - 2.7 8.4 17.7 2.9 8.3 17.7 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DDHD PF02862.17 CDJ46306.1 - 2.9 8.0 14.6 3 8.0 14.6 1.1 1 0 0 1 1 1 0 DDHD domain FAM176 PF14851.6 CDJ46306.1 - 3.3 7.3 12.4 4 7.1 12.4 1.2 1 0 0 1 1 1 0 FAM176 family G6B PF15096.6 CDJ46306.1 - 4.6 7.0 6.7 5 6.8 6.7 1.1 1 0 0 1 1 1 0 G6B family TFIIA PF03153.13 CDJ46306.1 - 4.7 7.1 39.0 4.6 7.1 39.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ46306.1 - 5.4 6.7 17.7 5.2 6.8 17.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2464 PF10240.9 CDJ46306.1 - 5.5 6.5 12.6 5.6 6.5 12.6 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 Membralin PF09746.9 CDJ46306.1 - 6.6 5.7 8.8 6 5.8 8.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein Pex14_N PF04695.13 CDJ46306.1 - 6.7 7.4 25.4 8 7.1 25.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PepSY_TM PF03929.16 CDJ46306.1 - 6.8 6.3 8.4 7 6.2 8.4 1.1 1 0 0 1 1 1 0 PepSY-associated TM region ALMT PF11744.8 CDJ46306.1 - 8.8 5.0 12.7 8.2 5.1 12.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter NPR3 PF03666.13 CDJ46306.1 - 8.8 5.0 15.9 8.8 5.0 15.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PAT1 PF09770.9 CDJ46306.1 - 8.8 4.4 30.1 9 4.4 30.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPSF100_C PF13299.6 CDJ46306.1 - 8.9 6.5 14.2 11 6.1 14.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Band_3_cyto PF07565.13 CDJ46306.1 - 9.7 5.9 15.8 9.3 6.0 15.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2232 PF09991.9 CDJ46307.1 - 2 7.5 4.6 2.2 7.4 4.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) TFIIA PF03153.13 CDJ46307.1 - 2.1 8.3 26.5 2.3 8.1 26.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2868 PF11067.8 CDJ46307.1 - 2.2 7.7 20.7 2.3 7.6 20.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) XRN_M PF17846.1 CDJ46307.1 - 4.2 6.2 6.9 4.5 6.1 6.9 1.0 1 0 0 1 1 1 0 Xrn1 helical domain RAB3GAP2_N PF14655.6 CDJ46307.1 - 5.1 6.2 15.1 6 6.0 15.1 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Hydin_ADK PF17213.3 CDJ46307.1 - 6 7.1 19.1 6.8 6.9 19.1 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF1513 PF07433.11 CDJ46307.1 - 8.4 5.4 16.8 9.5 5.2 16.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) DUF4148 PF13663.6 CDJ46308.1 - 0.18 12.0 37.2 3.2 8.0 3.2 5.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4148) Phasin PF05597.11 CDJ46309.1 - 0.18 11.8 20.0 2.3 8.3 10.7 2.6 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PMC2NT PF08066.12 CDJ46309.1 - 3.5 8.4 6.2 6.5 7.5 0.2 3.0 2 1 1 3 3 3 0 PMC2NT (NUC016) domain DUF2433 PF10360.9 CDJ46309.1 - 6.2 6.9 6.7 2.3 8.4 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2433) Methyltr_RsmB-F PF01189.17 CDJ46310.1 - 3.5e-21 75.8 0.0 8.3e-14 51.7 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F BTB_2 PF02214.22 CDJ46312.1 - 3.1e-14 53.1 0.0 1e-13 51.4 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Chorion_2 PF03964.15 CDJ46312.1 - 4.5 8.2 11.7 1.9 9.4 4.9 2.6 2 0 0 2 2 2 0 Chorion family 2 SUV3_C PF12513.8 CDJ46313.1 - 3.4e-11 42.9 0.1 6.6e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 CDJ46313.1 - 1.4e-06 28.1 0.1 3.4e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 CDJ46313.1 - 0.0016 18.8 0.0 0.011 16.1 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ATG27 PF09451.10 CDJ46313.1 - 0.042 13.7 2.9 0.1 12.5 2.9 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 FAD_binding_3 PF01494.19 CDJ46314.1 - 1.1e-22 80.8 4.0 1.2e-13 51.1 1.0 4.7 3 2 1 5 5 5 3 FAD binding domain Ribosomal_L12 PF00542.19 CDJ46315.1 - 6.5e-20 71.3 0.9 6.5e-20 71.3 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CDJ46315.1 - 7.3e-15 54.4 1.1 7.3e-15 54.4 1.1 3.0 3 0 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain DUF1002 PF06207.11 CDJ46315.1 - 1.3 8.5 5.0 0.35 10.4 2.3 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) IBN_N PF03810.19 CDJ46316.1 - 1.2e-06 28.3 0.2 1.9e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain IL32 PF15225.6 CDJ46316.1 - 0.073 13.4 0.3 1.9 8.9 0.1 2.2 1 1 1 2 2 2 0 Interleukin 32 Peptidase_M99_m PF17130.4 CDJ46317.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 RPN6_N PF18055.1 CDJ46317.1 - 0.15 12.5 0.1 1 9.7 0.1 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain rve PF00665.26 CDJ46320.1 - 1.9e-17 63.5 0.2 5.4e-17 62.1 0.1 1.9 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ46320.1 - 2.3e-17 62.8 1.2 2.3e-17 62.8 1.2 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CDJ46320.1 - 2.3e-16 60.0 0.8 4.8e-16 59.0 0.4 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ46320.1 - 7.8e-06 25.9 0.0 1.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CDJ46320.1 - 6.4e-05 23.1 0.6 0.00019 21.6 0.6 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDJ46320.1 - 0.0013 18.4 0.1 0.36 10.7 0.0 2.5 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 CDJ46321.1 - 1e-20 74.2 0.0 1.6e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) N6_N4_Mtase PF01555.18 CDJ46322.1 - 0.079 12.7 0.7 2.8e+02 1.0 0.0 3.8 4 2 0 4 4 4 0 DNA methylase DUF3522 PF12036.8 CDJ46322.1 - 0.11 12.8 0.3 0.22 11.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) DUF2722 PF10846.8 CDJ46324.1 - 0.0022 17.0 3.0 0.0025 16.8 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ46324.1 - 0.0074 15.9 8.6 0.0098 15.5 8.6 1.1 1 0 0 1 1 1 1 Spt20 family DUF3328 PF11807.8 CDJ46324.1 - 0.065 13.0 0.4 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Suf PF05843.14 CDJ46324.1 - 0.29 11.1 4.0 0.39 10.7 4.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAD_binding_2 PF00890.24 CDJ46326.1 - 3.6e-39 135.0 0.8 5.1e-39 134.5 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CDJ46326.1 - 0.00014 21.2 0.3 0.00026 20.3 0.2 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDJ46326.1 - 0.0014 18.0 0.4 0.0019 17.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 CDJ46326.1 - 0.0036 16.6 0.1 0.0058 15.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 CDJ46326.1 - 0.0042 16.2 2.5 0.0071 15.5 2.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 CDJ46326.1 - 0.061 12.0 1.1 0.12 11.0 1.1 1.5 1 0 0 1 1 1 0 HI0933-like protein DEAD PF00270.29 CDJ46327.1 - 2.4e-16 60.0 1.0 1.6e-12 47.6 0.2 5.3 4 2 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ46327.1 - 3.3e-16 59.6 0.0 3.3e-16 59.6 0.0 3.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Gti1_Pac2 PF09729.9 CDJ46328.1 - 0.36 10.9 14.8 0.36 10.9 14.8 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family FAM76 PF16046.5 CDJ46328.1 - 0.55 9.5 19.6 0.55 9.5 19.6 1.0 1 0 0 1 1 1 0 FAM76 protein DUF4746 PF15928.5 CDJ46328.1 - 0.83 9.0 12.2 0.85 9.0 12.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1764 PF08576.10 CDJ46328.1 - 1.4 9.9 12.9 1.8 9.5 12.9 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CPSF100_C PF13299.6 CDJ46328.1 - 2.3 8.4 13.4 2.7 8.1 13.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RPOL_N PF14700.6 CDJ46328.1 - 2.9 7.2 20.0 3.4 7.0 20.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Tim54 PF11711.8 CDJ46328.1 - 3.4 6.3 16.6 3.5 6.3 16.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SelP_N PF04592.14 CDJ46328.1 - 4.1 6.7 39.0 4.8 6.5 39.0 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SLC12 PF03522.15 CDJ46328.1 - 4.7 6.1 19.1 5 6.0 19.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 CDJ46328.1 - 4.8 5.5 16.1 4.7 5.6 16.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 SpoIIP PF07454.11 CDJ46328.1 - 5.2 6.4 18.8 5.4 6.4 18.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NST1 PF13945.6 CDJ46328.1 - 5.8 7.0 26.0 8.6 6.4 26.0 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator MCM_bind PF09739.9 CDJ46328.1 - 6.7 5.0 17.0 7 5.0 17.0 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Sec62 PF03839.16 CDJ46328.1 - 7.1 6.1 14.7 7.3 6.0 14.7 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 FAM176 PF14851.6 CDJ46328.1 - 7.9 6.1 12.6 9.7 5.8 12.6 1.2 1 0 0 1 1 1 0 FAM176 family DDHD PF02862.17 CDJ46328.1 - 8.3 6.5 16.1 9.7 6.3 16.1 1.2 1 0 0 1 1 1 0 DDHD domain PTPRCAP PF15713.5 CDJ46328.1 - 8.4 6.7 21.2 9.2 6.5 21.2 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Pex14_N PF04695.13 CDJ46328.1 - 8.6 7.0 30.4 11 6.7 30.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EF-hand_1 PF00036.32 CDJ46330.1 - 1.3e-28 96.4 8.4 3.6e-07 29.3 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CDJ46330.1 - 2e-25 87.1 8.0 1.1e-07 31.1 0.2 5.2 5 0 0 5 5 5 4 EF hand Pkinase PF00069.25 CDJ46330.1 - 2.4e-24 86.2 0.0 3.7e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_6 PF13405.6 CDJ46330.1 - 2.5e-24 83.1 2.6 1.1e-05 24.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CDJ46330.1 - 3e-23 82.0 4.5 8.8e-11 42.1 0.6 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ46330.1 - 5.3e-11 42.2 8.4 0.00071 19.4 0.2 4.3 3 1 1 4 4 4 4 EF-hand domain pair Pkinase_Tyr PF07714.17 CDJ46330.1 - 9.1e-08 31.7 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_4 PF12763.7 CDJ46330.1 - 5e-07 29.6 6.0 0.00099 19.0 0.1 3.5 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ46330.1 - 2.9e-06 27.6 0.6 0.14 12.5 0.4 3.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CDJ46330.1 - 0.011 15.6 0.5 0.18 11.7 0.1 2.7 2 0 0 2 2 2 0 EF hand SPX PF03105.19 CDJ46331.1 - 0.83 9.5 18.1 0.99 9.3 18.1 1.1 1 0 0 1 1 1 0 SPX domain Secretin_N_2 PF07655.13 CDJ46331.1 - 2.1 8.9 19.8 4.2 8.0 19.8 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Cwf_Cwc_15 PF04889.12 CDJ46331.1 - 8.5 6.0 20.8 14 5.3 20.8 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Apt1 PF10351.9 CDJ46331.1 - 9.9 4.9 17.9 10 4.8 17.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ46332.1 - 9.6 4.8 9.0 5.7 5.6 7.3 1.5 2 0 0 2 2 2 0 Presenilin DUF2722 PF10846.8 CDJ46334.1 - 7.6e-05 21.8 5.3 7.6e-05 21.8 5.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ46334.1 - 0.0049 15.6 9.5 0.0049 15.6 9.5 2.3 2 1 0 2 2 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ46334.1 - 0.0051 16.5 13.1 0.0051 16.5 13.1 2.2 2 0 0 2 2 2 1 Spt20 family PCI PF01399.27 CDJ46334.1 - 0.0081 16.7 0.1 0.0081 16.7 0.1 2.0 2 0 0 2 2 2 1 PCI domain TFIIA PF03153.13 CDJ46334.1 - 0.015 15.3 29.5 0.026 14.6 14.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hep_59 PF07052.11 CDJ46334.1 - 0.054 14.3 5.2 0.07 13.9 2.9 2.0 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Sin_N PF04801.13 CDJ46334.1 - 0.081 12.1 11.4 0.038 13.2 5.6 2.2 2 0 0 2 2 2 0 Sin-like protein conserved region YppG PF14179.6 CDJ46334.1 - 0.083 13.6 19.2 1.2 9.9 0.8 2.5 2 0 0 2 2 2 0 YppG-like protein dsDNA_bind PF01984.20 CDJ46334.1 - 0.087 13.1 16.1 0.35 11.2 11.4 2.8 2 0 0 2 2 2 0 Double-stranded DNA-binding domain UNC80 PF15778.5 CDJ46334.1 - 0.14 11.8 5.8 0.049 13.3 1.7 2.2 2 1 1 3 3 3 0 Cation channel complex component UNC80 Suf PF05843.14 CDJ46334.1 - 0.27 11.2 7.7 0.051 13.5 3.1 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) ANAPC_CDC26 PF10471.9 CDJ46334.1 - 1.2 10.1 26.1 0.72 10.7 13.9 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Neuregulin PF02158.15 CDJ46334.1 - 2.4 7.5 8.3 7.5 5.8 2.2 2.2 2 0 0 2 2 2 0 Neuregulin intracellular region DUF2681 PF10883.8 CDJ46334.1 - 2.4 8.6 17.1 6.5 7.2 12.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF1178 PF06676.11 CDJ46334.1 - 3.8 7.9 11.8 0.86 10.0 3.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Vps54 PF07928.12 CDJ46334.1 - 5 7.6 11.3 12 6.4 0.3 3.2 3 0 0 3 3 3 0 Vps54-like protein Zea_mays_MuDR PF05928.11 CDJ46334.1 - 6.6 6.3 8.2 15 5.1 8.2 1.5 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) DUF4834 PF16118.5 CDJ46334.1 - 9.5 7.3 10.0 1.7 9.7 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SUIM_assoc PF16619.5 CDJ46335.1 - 0.00049 20.1 2.3 0.00049 20.1 2.3 23.1 6 5 8 14 14 14 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ46336.1 - 0.00033 20.8 34.0 0.0004 20.5 34.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FapA PF03961.13 CDJ46336.1 - 0.0015 17.2 6.3 0.0018 17.0 6.3 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 CDJ46336.1 - 0.0017 18.0 11.9 0.002 17.8 11.9 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Spc7_N PF15402.6 CDJ46336.1 - 0.019 13.3 7.3 0.023 13.0 7.3 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Neur_chan_memb PF02932.16 CDJ46336.1 - 0.04 14.0 3.8 0.037 14.1 3.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF775 PF05603.12 CDJ46336.1 - 0.045 13.3 10.7 0.082 12.4 10.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DDHD PF02862.17 CDJ46336.1 - 0.048 13.8 5.2 0.047 13.8 5.2 1.2 1 0 0 1 1 1 0 DDHD domain Myco_haema PF05692.12 CDJ46336.1 - 0.054 12.5 5.6 0.073 12.0 5.6 1.1 1 0 0 1 1 1 0 Mycoplasma haemagglutinin TFB6 PF17110.5 CDJ46336.1 - 0.073 12.8 4.5 0.11 12.3 4.5 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH eIF-3_zeta PF05091.12 CDJ46336.1 - 0.11 11.5 12.9 0.11 11.4 12.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Serinc PF03348.15 CDJ46336.1 - 0.12 11.2 2.4 0.12 11.3 2.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.12 CDJ46336.1 - 0.15 11.9 8.5 0.19 11.5 8.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 CDJ46336.1 - 0.16 10.2 24.9 0.19 10.0 24.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YABBY PF04690.13 CDJ46336.1 - 0.18 12.4 8.0 0.31 11.6 8.0 1.4 1 0 0 1 1 1 0 YABBY protein DUF2464 PF10240.9 CDJ46336.1 - 0.21 11.2 9.1 0.29 10.7 9.1 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 EIF4E-T PF10477.9 CDJ46336.1 - 0.22 10.3 16.2 0.3 9.9 16.2 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF1980 PF09323.10 CDJ46336.1 - 0.29 11.0 4.2 0.38 10.7 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PRKG1_interact PF15898.5 CDJ46336.1 - 0.34 11.8 18.9 0.53 11.2 18.9 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain HemX PF04375.14 CDJ46336.1 - 0.53 9.5 32.4 0.74 9.0 32.4 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase AIF_C PF14721.6 CDJ46336.1 - 0.58 10.5 6.4 1.2 9.5 6.4 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SID-1_RNA_chan PF13965.6 CDJ46336.1 - 0.88 7.9 2.6 1 7.7 2.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 CDJ46336.1 - 0.89 8.3 14.0 1.2 7.8 14.0 1.1 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 CDJ46336.1 - 1 8.7 10.9 1.3 8.4 10.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AAA_23 PF13476.6 CDJ46336.1 - 1.1 9.8 16.5 1.8 9.0 16.5 1.4 1 0 0 1 1 1 0 AAA domain CLN3 PF02487.17 CDJ46336.1 - 1.1 8.2 6.6 1.3 8.0 6.6 1.1 1 0 0 1 1 1 0 CLN3 protein YlqD PF11068.8 CDJ46336.1 - 1.1 9.6 34.4 1.5 9.2 34.4 1.2 1 0 0 1 1 1 0 YlqD protein RskA PF10099.9 CDJ46336.1 - 1.1 9.5 36.4 39 4.5 36.4 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA MelC1 PF06236.11 CDJ46336.1 - 1.2 9.2 12.1 1.3 9.2 10.9 1.7 1 1 0 1 1 1 0 Tyrosinase co-factor MelC1 CCDC53 PF10152.9 CDJ46336.1 - 1.5 9.3 18.9 1.8 9.0 14.1 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex STAC2_u1 PF16664.5 CDJ46336.1 - 1.6 9.2 9.5 2.8 8.4 9.5 1.4 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 FAM60A PF15396.6 CDJ46336.1 - 1.9 8.4 9.1 2.6 8.0 9.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Ca_chan_IQ PF08763.11 CDJ46336.1 - 2 8.7 4.6 4.2 7.7 4.6 1.6 1 1 0 1 1 1 0 Voltage gated calcium channel IQ domain Ndc1_Nup PF09531.10 CDJ46336.1 - 2.2 6.9 10.0 2.6 6.6 10.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRP36 PF06102.12 CDJ46336.1 - 2.4 8.1 18.1 8.2 6.4 18.8 1.5 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 OmpH PF03938.14 CDJ46336.1 - 3.3 8.1 39.3 6.5 7.1 39.3 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.19 CDJ46336.1 - 4.4 5.1 16.0 5.6 4.7 16.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MMR1 PF08505.10 CDJ46336.1 - 7 6.9 16.9 9.7 6.4 16.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Gastrin PF00918.17 CDJ46336.1 - 7.4 7.6 11.5 15 6.6 11.5 1.5 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Gti1_Pac2 PF09729.9 CDJ46336.1 - 8.3 6.5 10.4 12 5.9 10.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Menin PF05053.13 CDJ46337.1 - 0.0012 17.3 3.8 0.0013 17.2 3.8 1.1 1 0 0 1 1 1 1 Menin TFIIA PF03153.13 CDJ46337.1 - 0.0015 18.6 8.6 0.0017 18.4 8.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ46337.1 - 0.0021 17.7 10.7 0.0033 17.1 10.7 1.3 1 0 0 1 1 1 1 Spt20 family DUF3824 PF12868.7 CDJ46337.1 - 0.0022 18.7 4.2 0.0022 18.7 4.2 2.1 2 0 0 2 2 2 1 Domain of unknwon function (DUF3824) RP-C_C PF11800.8 CDJ46337.1 - 0.0037 17.4 7.4 0.0037 17.4 7.4 1.7 2 0 0 2 2 2 1 Replication protein C C-terminal region DUF3682 PF12446.8 CDJ46337.1 - 0.0049 17.3 6.1 0.0049 17.3 6.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3682) DALR_2 PF09190.11 CDJ46337.1 - 0.015 15.7 0.0 0.015 15.7 0.0 3.0 3 1 0 3 3 3 0 DALR domain Androgen_recep PF02166.16 CDJ46337.1 - 0.11 11.3 12.9 0.16 10.8 12.9 1.2 1 0 0 1 1 1 0 Androgen receptor Asparaginase PF00710.20 CDJ46337.1 - 0.12 11.9 1.0 0.21 11.1 0.6 1.6 2 0 0 2 2 2 0 Asparaginase, N-terminal RskA PF10099.9 CDJ46337.1 - 0.24 11.7 11.9 0.39 11.0 11.9 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA O-antigen_lig PF13425.6 CDJ46337.1 - 0.42 9.3 2.0 0.57 8.9 2.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Suf PF05843.14 CDJ46337.1 - 0.65 9.9 9.2 0.019 14.9 3.3 1.4 2 0 0 2 2 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ46337.1 - 0.66 8.7 7.5 0.89 8.2 7.5 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ46337.1 - 1.2 7.0 5.1 1.4 6.7 5.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sld3_N PF18523.1 CDJ46337.1 - 1.3 9.1 7.3 0.11 12.6 2.0 1.9 2 0 0 2 2 2 0 Sld3 N-terminal domain K_channel_TID PF07941.11 CDJ46337.1 - 1.9 9.0 11.9 3.6 8.1 11.9 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF4820 PF16091.5 CDJ46337.1 - 2.9 7.2 10.9 0.14 11.5 4.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) CTU2 PF10288.9 CDJ46337.1 - 6.3 7.1 10.1 1 9.6 4.6 2.0 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Med3 PF11593.8 CDJ46337.1 - 6.5 5.8 23.1 27 3.8 23.1 1.6 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal SpoIIP PF07454.11 CDJ46339.1 - 0.56 9.6 15.4 0.48 9.8 3.8 2.5 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SID-1_RNA_chan PF13965.6 CDJ46339.1 - 0.7 8.2 3.8 3.7 5.9 0.1 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 SpoVR PF04293.13 CDJ46339.1 - 1.1 7.9 14.6 0.026 13.2 4.6 2.2 2 0 0 2 2 2 0 SpoVR like protein Sporozoite_P67 PF05642.11 CDJ46339.1 - 2.3 6.2 16.6 0.3 9.1 0.9 2.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Sin_N PF04801.13 CDJ46339.1 - 4.7 6.3 37.5 4.2 6.5 16.0 2.5 2 0 0 2 2 2 0 Sin-like protein conserved region Med19 PF10278.9 CDJ46339.1 - 7 6.5 7.5 17 5.3 0.5 2.3 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.12 CDJ46339.1 - 9.9 5.9 20.2 7 6.4 5.2 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RAP PF08373.10 CDJ46340.1 - 0.004 17.2 0.2 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 RAP domain PDGF PF00341.17 CDJ46340.1 - 0.064 13.6 0.1 0.064 13.6 0.1 4.8 5 0 0 5 5 5 0 PDGF/VEGF domain TMEM51 PF15345.6 CDJ46341.1 - 0.0037 17.1 11.5 0.0037 17.1 11.5 4.4 2 1 2 4 4 4 1 Transmembrane protein 51 RAP1 PF07218.11 CDJ46341.1 - 8.1 4.6 7.5 9.7 4.3 7.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ46342.1 - 0.0048 16.5 39.7 0.0048 16.5 39.7 2.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ46342.1 - 0.039 12.1 65.8 0.05 11.7 65.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DEAD PF00270.29 CDJ46343.1 - 1.2e-10 41.4 0.0 1.2e-10 41.4 0.0 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ46343.1 - 0.0015 18.8 1.9 0.0018 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Spt20 PF12090.8 CDJ46343.1 - 0.2 11.3 16.8 0.44 10.1 16.8 1.5 1 0 0 1 1 1 0 Spt20 family Peptidase_M24 PF00557.24 CDJ46344.1 - 1e-15 58.0 4.9 7.3e-12 45.4 0.4 2.3 1 1 0 2 2 2 2 Metallopeptidase family M24 CDK2AP PF09806.9 CDJ46344.1 - 0.004 17.3 8.1 0.004 17.3 8.1 2.8 3 0 0 3 3 3 2 Cyclin-dependent kinase 2-associated protein IMUP PF15761.5 CDJ46345.1 - 0.0087 16.7 6.5 0.0087 16.7 6.5 3.7 4 1 0 4 4 4 1 Immortalisation up-regulated protein DUF4366 PF14283.6 CDJ46345.1 - 0.013 15.5 3.5 0.013 15.5 3.5 5.2 3 2 1 4 4 4 0 Domain of unknown function (DUF4366) Pkinase PF00069.25 CDJ46346.1 - 5.4e-22 78.4 0.3 9.6e-22 77.6 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ46346.1 - 8.1e-15 54.8 0.4 1.7e-14 53.7 0.4 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ46346.1 - 0.00049 19.5 1.7 0.00093 18.6 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Atg14 PF10186.9 CDJ46346.1 - 0.0033 16.6 1.3 1.6 7.8 1.0 2.1 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5320 PF17253.2 CDJ46346.1 - 0.011 16.7 1.5 0.019 16.0 1.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) OmpH PF03938.14 CDJ46346.1 - 0.022 15.1 7.6 0.031 14.6 7.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Choline_kinase PF01633.20 CDJ46346.1 - 0.05 13.2 0.4 0.32 10.6 0.0 1.9 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CDJ46346.1 - 0.14 12.1 1.9 0.9 9.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DivIC PF04977.15 CDJ46346.1 - 0.22 11.3 7.2 0.4 10.5 7.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Spt20 PF12090.8 CDJ46346.1 - 1.3 8.6 9.7 1.8 8.2 9.7 1.1 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ46346.1 - 3.3 6.6 16.4 4 6.3 16.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Mito_fiss_reg PF05308.11 CDJ46347.1 - 0.065 13.3 8.8 0.062 13.4 8.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator TFIIA PF03153.13 CDJ46347.1 - 0.096 12.7 17.5 0.11 12.5 17.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ46347.1 - 0.096 11.6 14.5 0.093 11.7 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TMEM171 PF15471.6 CDJ46347.1 - 0.13 11.2 4.8 0.16 10.9 4.8 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 Amidohydro_2 PF04909.14 CDJ46347.1 - 0.37 10.5 4.2 0.4 10.4 4.2 1.1 1 0 0 1 1 1 0 Amidohydrolase Pex14_N PF04695.13 CDJ46347.1 - 0.61 10.7 23.4 0.75 10.4 23.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ46347.1 - 0.94 9.0 22.1 1 8.9 22.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF2076 PF09849.9 CDJ46347.1 - 1 9.4 21.1 1.1 9.3 21.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) BAT2_N PF07001.11 CDJ46347.1 - 1.7 9.0 13.9 2.1 8.8 13.9 1.1 1 0 0 1 1 1 0 BAT2 N-terminus DUF4366 PF14283.6 CDJ46347.1 - 2.5 8.1 7.5 3 7.9 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) BRF1 PF07741.13 CDJ46347.1 - 4.5 7.7 7.6 5.9 7.3 7.6 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain SOG2 PF10428.9 CDJ46347.1 - 4.9 6.3 10.0 5.4 6.1 10.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CDJ46347.1 - 4.9 5.8 6.2 5 5.8 6.2 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ46347.1 - 6.7 4.9 12.6 6.4 4.9 12.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IER PF05760.12 CDJ46347.1 - 6.8 6.9 13.7 7.3 6.8 13.7 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) FeoB_associated PF12669.7 CDJ46348.1 - 0.02 15.3 0.2 0.02 15.3 0.2 1.7 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Pex14_N PF04695.13 CDJ46348.1 - 9 6.9 11.1 6.2 7.5 0.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.9 CDJ46349.1 - 0.00011 22.5 5.2 0.00011 22.5 5.2 14.4 6 5 5 11 11 11 3 Anti-sigma-K factor rskA Med3 PF11593.8 CDJ46349.1 - 0.0011 18.3 9.6 0.0011 18.3 9.6 16.1 9 4 8 17 17 16 1 Mediator complex subunit 3 fungal Nudix_hydro PF18290.1 CDJ46350.1 - 0.15 12.1 0.0 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 Nudix hydrolase domain Nucleotid_trans PF03407.16 CDJ46353.1 - 2.8 7.8 28.2 2.5 8.0 0.5 5.0 1 1 4 5 5 5 0 Nucleotide-diphospho-sugar transferase HA2 PF04408.23 CDJ46354.1 - 7.7e-19 68.0 0.0 7.7e-19 68.0 0.0 3.6 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ46354.1 - 8.2e-17 61.3 0.0 1.6e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ46354.1 - 9.5e-13 48.5 0.0 2.2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ46354.1 - 0.00019 21.3 0.0 0.0005 19.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 CDJ46354.1 - 0.0003 19.9 0.7 0.00068 18.8 0.7 1.6 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CDJ46354.1 - 0.00094 19.5 3.8 0.0023 18.2 0.1 3.3 2 2 1 3 3 3 1 AAA domain AAA_19 PF13245.6 CDJ46354.1 - 0.0014 19.0 0.0 0.0045 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CDJ46354.1 - 0.053 13.1 0.1 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CDJ46354.1 - 0.1 13.0 0.1 0.1 13.0 0.1 4.2 1 1 2 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 CDJ46354.1 - 2 8.9 0.0 2 8.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain Serpin PF00079.20 CDJ46355.1 - 4.4e-76 256.6 0.0 5.2e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) FAM220 PF15487.6 CDJ46356.1 - 5.5 6.5 4.5 7.2 6.2 4.5 1.2 1 0 0 1 1 1 0 FAM220 family Trypan_PARP PF05887.11 CDJ46357.1 - 0.0088 16.0 3.0 0.015 15.3 3.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Nha1_C PF08619.10 CDJ46357.1 - 4.6 6.4 32.8 6.3 5.9 32.8 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus SR-25 PF10500.9 CDJ46359.1 - 2.7e-05 23.9 13.0 3e-05 23.7 13.0 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Spc7_N PF15402.6 CDJ46359.1 - 0.042 12.1 23.7 0.05 11.9 23.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 AF-4 PF05110.13 CDJ46359.1 - 0.065 11.3 24.9 0.098 10.7 24.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pex14_N PF04695.13 CDJ46359.1 - 0.069 13.8 33.7 0.085 13.5 33.7 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CCSAP PF15748.5 CDJ46359.1 - 0.15 12.2 22.9 0.18 11.9 22.9 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Suf PF05843.14 CDJ46359.1 - 0.34 10.9 22.3 0.36 10.8 22.3 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SelP_N PF04592.14 CDJ46359.1 - 0.52 9.7 16.9 0.6 9.5 16.9 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TCP PF03634.13 CDJ46359.1 - 0.57 10.7 15.5 0.66 10.5 15.5 1.0 1 0 0 1 1 1 0 TCP family transcription factor IMUP PF15761.5 CDJ46359.1 - 0.7 10.6 16.7 1.1 10.0 16.7 1.4 1 1 0 1 1 1 0 Immortalisation up-regulated protein Presenilin PF01080.17 CDJ46359.1 - 0.95 8.2 18.8 0.99 8.1 18.8 1.0 1 0 0 1 1 1 0 Presenilin ECM1 PF05782.11 CDJ46359.1 - 2.1 7.2 17.7 2.4 7.0 17.7 1.0 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) SseC PF04888.12 CDJ46359.1 - 2.3 7.7 7.6 3.2 7.2 7.6 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family FAM60A PF15396.6 CDJ46359.1 - 3.6 7.5 12.0 4.6 7.2 12.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Connexin PF00029.19 CDJ46359.1 - 4.2 7.0 6.5 4.8 6.9 6.5 1.2 1 0 0 1 1 1 0 Connexin CEND1 PF15677.5 CDJ46359.1 - 4.4 7.9 11.2 5.5 7.5 11.2 1.2 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 60KD_IMP PF02096.20 CDJ46359.1 - 4.6 7.1 8.5 5.5 6.9 8.5 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein PepSY_TM PF03929.16 CDJ46359.1 - 5.1 6.7 7.5 5.9 6.5 7.5 1.2 1 0 0 1 1 1 0 PepSY-associated TM region PAT1 PF09770.9 CDJ46359.1 - 5.5 5.1 24.7 6.2 5.0 24.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 CDJ46359.1 - 6.4 6.6 38.2 8 6.3 38.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EIIBC-GUT_N PF03612.14 CDJ46359.1 - 7.6 6.2 10.6 10 5.8 10.6 1.4 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Endostatin PF06482.11 CDJ46359.1 - 8.4 5.7 15.8 9.5 5.6 15.8 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Tim54 PF11711.8 CDJ46359.1 - 9.7 4.9 12.3 11 4.7 12.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RskA PF10099.9 CDJ46360.1 - 0.006 16.9 6.9 0.006 16.9 6.9 6.2 1 1 2 3 3 3 1 Anti-sigma-K factor rskA LETM1 PF07766.13 CDJ46360.1 - 0.068 12.5 0.4 0.068 12.5 0.4 3.8 3 1 1 4 4 4 0 LETM1-like protein DUF2052 PF09747.9 CDJ46361.1 - 0.00035 20.8 10.3 0.00038 20.6 10.3 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DcuC PF03606.15 CDJ46361.1 - 0.025 13.0 0.4 0.036 12.5 0.4 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Tub_N PF16322.5 CDJ46361.1 - 0.027 14.9 10.3 0.032 14.6 10.3 1.1 1 0 0 1 1 1 0 Tubby N-terminal TFIIA PF03153.13 CDJ46361.1 - 0.069 13.1 11.9 0.083 12.9 11.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RIFIN PF02009.16 CDJ46361.1 - 0.081 12.8 17.8 0.12 12.3 17.8 1.3 1 0 0 1 1 1 0 Rifin CDC45 PF02724.14 CDJ46361.1 - 0.091 11.0 8.9 0.1 10.9 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein GCD14 PF08704.10 CDJ46361.1 - 0.11 12.2 5.8 0.14 11.8 5.8 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Paf1 PF03985.13 CDJ46361.1 - 0.18 10.8 16.2 0.23 10.4 16.2 1.1 1 0 0 1 1 1 0 Paf1 SWI-SNF_Ssr4 PF08549.10 CDJ46361.1 - 0.26 9.9 17.8 0.3 9.7 17.8 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) RR_TM4-6 PF06459.12 CDJ46361.1 - 0.32 10.8 17.9 0.38 10.5 17.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 CDJ46361.1 - 0.36 10.6 7.4 0.5 10.1 7.4 1.4 1 0 0 1 1 1 0 Connexin DNA_pol_phi PF04931.13 CDJ46361.1 - 0.5 8.4 12.5 0.6 8.1 12.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF4813 PF16072.5 CDJ46361.1 - 0.5 10.0 26.7 0.078 12.6 13.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) Tim54 PF11711.8 CDJ46361.1 - 1.4 7.6 12.8 2 7.1 12.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.15 CDJ46361.1 - 1.6 7.4 13.1 1.9 7.1 13.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.10 CDJ46361.1 - 2 8.7 20.3 3.1 8.1 20.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4045 PF13254.6 CDJ46361.1 - 2.3 7.8 17.0 2.7 7.5 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Presenilin PF01080.17 CDJ46361.1 - 2.4 6.8 14.2 3.1 6.5 14.2 1.1 1 0 0 1 1 1 0 Presenilin DUF3807 PF12720.7 CDJ46361.1 - 2.6 8.3 18.3 4.9 7.4 18.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) O-antigen_lig PF13425.6 CDJ46361.1 - 2.7 6.7 5.9 2.9 6.6 5.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF913 PF06025.12 CDJ46361.1 - 2.9 6.8 8.3 3.2 6.7 8.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Membralin PF09746.9 CDJ46361.1 - 3.3 6.7 9.2 4.1 6.3 9.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein SLC12 PF03522.15 CDJ46361.1 - 3.4 6.6 12.2 4.2 6.3 12.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Draxin PF15550.6 CDJ46361.1 - 3.5 7.4 12.4 4.1 7.2 12.4 1.0 1 0 0 1 1 1 0 Draxin DUF966 PF06136.13 CDJ46361.1 - 3.7 7.2 11.2 3.8 7.1 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Paramyxo_ncap PF00973.19 CDJ46361.1 - 3.9 6.3 10.2 4.4 6.1 10.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CLN3 PF02487.17 CDJ46361.1 - 4.3 6.3 7.4 5.4 5.9 7.4 1.2 1 0 0 1 1 1 0 CLN3 protein TRAP_alpha PF03896.16 CDJ46361.1 - 4.4 6.4 9.1 6.2 5.9 9.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PE_PPE_C PF12484.8 CDJ46361.1 - 4.7 8.2 33.1 1.5 9.7 18.1 2.2 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal MDFI PF15316.6 CDJ46361.1 - 4.8 7.3 10.2 6.7 6.8 10.2 1.2 1 0 0 1 1 1 0 MyoD family inhibitor DDRGK PF09756.9 CDJ46361.1 - 5.5 6.5 23.1 8.4 5.9 23.1 1.3 1 0 0 1 1 1 0 DDRGK domain FAM176 PF14851.6 CDJ46361.1 - 6.5 6.4 11.7 11 5.7 11.7 1.4 1 0 0 1 1 1 0 FAM176 family Zip PF02535.22 CDJ46361.1 - 8.4 5.5 8.7 13 4.9 8.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PPL5 PF18168.1 CDJ46361.1 - 8.5 5.6 10.2 11 5.2 10.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 XRN_M PF17846.1 CDJ46361.1 - 8.7 5.2 11.7 11 4.8 11.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain NPR3 PF03666.13 CDJ46361.1 - 9.8 4.8 13.2 12 4.5 13.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tfb4 PF03850.14 CDJ46361.1 - 9.9 5.6 7.0 12 5.3 7.0 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 Carb_anhydrase PF00194.21 CDJ46363.1 - 2e-18 66.9 8.4 4.3e-14 52.7 9.2 3.5 2 1 0 2 2 2 1 Eukaryotic-type carbonic anhydrase SR-25 PF10500.9 CDJ46363.1 - 5e-05 23.0 36.3 5.3e-05 22.9 2.0 3.5 2 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein DUF4207 PF13904.6 CDJ46363.1 - 0.00024 20.9 5.7 0.00024 20.9 5.7 4.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4207) DUF4638 PF15472.6 CDJ46363.1 - 0.053 13.3 0.5 0.053 13.3 0.5 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4638) SLC12 PF03522.15 CDJ46363.1 - 0.18 10.8 19.6 0.74 8.8 13.0 2.5 2 0 0 2 2 2 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ46363.1 - 0.6 10.1 29.4 0.22 11.5 1.3 2.4 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GramPos_pilinD1 PF16555.5 CDJ46363.1 - 2.4 8.3 22.6 0.054 13.7 6.0 2.7 3 0 0 3 3 3 0 Gram-positive pilin subunit D1, N-terminal domain Hep_59 PF07052.11 CDJ46365.1 - 1.3e-20 74.2 2.6 1.3e-20 74.2 2.6 2.4 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Nbs1_C PF08599.10 CDJ46365.1 - 5.8 7.1 6.1 0.96 9.6 1.2 2.3 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 Romo1 PF10247.9 CDJ46366.1 - 0.041 14.3 1.1 0.12 12.7 1.1 1.8 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF3685 PF12452.8 CDJ46366.1 - 0.13 12.0 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) DUF1269 PF06897.12 CDJ46366.1 - 0.51 10.7 7.5 1.3 9.3 7.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) RT_RNaseH PF17917.1 CDJ46367.1 - 2.9e-16 59.7 0.3 4e-16 59.2 0.3 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ46367.1 - 7.7e-06 25.9 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ46367.1 - 0.075 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like CTC1 PF15489.6 CDJ46367.1 - 0.08 10.4 0.0 0.11 10.0 0.0 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 TMEM171 PF15471.6 CDJ46368.1 - 0.052 12.5 0.4 0.052 12.5 0.4 2.2 2 1 0 2 2 2 0 Transmembrane protein family 171 Maf1 PF09174.10 CDJ46368.1 - 7.4 6.7 6.0 18 5.5 3.9 2.2 2 0 0 2 2 2 0 Maf1 regulator AP2 PF00847.20 CDJ46369.1 - 0.055 13.7 0.2 0.055 13.7 0.2 4.0 5 0 0 5 5 5 0 AP2 domain DUF5423 PF17461.2 CDJ46369.1 - 5.9 5.6 10.0 9.5 5.0 10.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) DnaJ PF00226.31 CDJ46370.1 - 3.9e-12 46.1 0.0 2.6e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 DnaJ domain Nop14 PF04147.12 CDJ46370.1 - 0.37 8.9 19.0 0.44 8.7 19.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CDJ46370.1 - 6 6.2 17.3 8.2 5.7 17.3 1.2 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 CDJ46370.1 - 7.6 6.8 14.5 12 6.1 14.5 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 CDJ46370.1 - 8.9 5.5 18.2 12 5.1 18.2 1.1 1 0 0 1 1 1 0 BUD22 NrsF PF06532.11 CDJ46370.1 - 9.9 5.8 17.5 0.93 9.2 4.1 2.1 2 0 0 2 2 2 0 Negative regulator of sigma F Pex14_N PF04695.13 CDJ46371.1 - 0.00024 21.8 31.1 0.0011 19.7 20.1 2.5 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region UPF0564 PF10595.9 CDJ46371.1 - 0.0023 17.1 7.2 0.0023 17.1 7.2 2.3 2 0 0 2 2 1 1 Uncharacterised protein family UPF0564 BCL_N PF04714.13 CDJ46371.1 - 0.086 12.9 2.7 0.24 11.5 2.7 1.7 1 0 0 1 1 1 0 BCL7, N-terminal conserver region Otopetrin PF03189.13 CDJ46371.1 - 0.093 11.5 6.4 0.18 10.6 1.5 2.2 2 0 0 2 2 2 0 Otopetrin DUF4407 PF14362.6 CDJ46371.1 - 0.13 11.6 31.8 0.23 10.8 31.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDJ46371.1 - 0.26 10.0 25.7 0.046 12.5 13.1 2.2 2 0 0 2 2 2 0 Presenilin Peptidase_S64 PF08192.11 CDJ46371.1 - 0.78 8.2 15.2 0.22 9.9 6.5 2.2 2 0 0 2 2 2 0 Peptidase family S64 TCP PF03634.13 CDJ46371.1 - 0.87 10.1 26.3 0.62 10.6 14.3 2.3 2 0 0 2 2 2 0 TCP family transcription factor V_ATPase_I PF01496.19 CDJ46371.1 - 1.2 6.9 25.3 1.8 6.4 15.9 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Asparaginase_2 PF01112.18 CDJ46371.1 - 1.7 7.6 12.0 1.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Asparaginase Ribosomal_60s PF00428.19 CDJ46371.1 - 4.1 8.1 19.6 1.7 9.3 0.1 2.5 3 0 0 3 3 2 0 60s Acidic ribosomal protein eIF-3_zeta PF05091.12 CDJ46371.1 - 5 6.0 36.4 0.13 11.2 21.6 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 CDJ46371.1 - 7.8 5.4 17.2 18 4.2 0.1 2.3 2 0 0 2 2 2 0 CLN3 protein Miga PF10265.9 CDJ46371.1 - 8.1 5.3 19.2 0.32 9.9 8.2 2.1 2 0 0 2 2 2 0 Mitoguardin DUF2722 PF10846.8 CDJ46372.1 - 2.2e-05 23.6 6.6 3.3e-05 23.0 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ46372.1 - 0.0037 17.9 2.9 0.0037 17.9 2.9 2.5 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAS_3 PF08447.12 CDJ46372.1 - 0.0052 17.0 0.1 2.7 8.3 0.1 2.4 2 0 0 2 2 2 1 PAS fold RNA_pol_Rpc4 PF05132.14 CDJ46372.1 - 0.026 15.0 0.0 0.026 15.0 0.0 3.0 2 1 0 2 2 1 0 RNA polymerase III RPC4 Peptidase_S49_N PF08496.10 CDJ46372.1 - 0.11 12.6 3.6 0.2 11.7 3.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sec62 PF03839.16 CDJ46372.1 - 0.12 11.9 0.2 0.19 11.2 0.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Tim54 PF11711.8 CDJ46372.1 - 0.24 10.1 6.4 0.41 9.4 6.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.8 CDJ46372.1 - 0.25 10.2 8.0 0.43 9.4 8.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Band_3_cyto PF07565.13 CDJ46372.1 - 0.27 11.0 3.4 0.45 10.3 3.4 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.12 CDJ46372.1 - 0.41 9.6 8.7 0.64 8.9 8.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4746 PF15928.5 CDJ46372.1 - 0.72 9.2 6.1 1.5 8.2 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF5327 PF17261.2 CDJ46372.1 - 0.73 10.6 13.4 1.9 9.3 13.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5327) SpoIIP PF07454.11 CDJ46372.1 - 0.74 9.2 8.9 1.2 8.6 8.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Neur_chan_memb PF02932.16 CDJ46372.1 - 1.1 9.3 2.8 2.7 8.0 2.8 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TERB2 PF15101.6 CDJ46372.1 - 1.8 8.6 12.9 3.1 7.8 12.9 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Suf PF05843.14 CDJ46372.1 - 3.1 7.7 10.0 5.6 6.9 10.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0560 PF10577.9 CDJ46372.1 - 4.6 5.6 12.0 7.8 4.9 12.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Connexin PF00029.19 CDJ46372.1 - 5 6.8 7.0 9.1 6.0 7.0 1.3 1 0 0 1 1 1 0 Connexin TFB6 PF17110.5 CDJ46372.1 - 5.1 6.8 5.9 9.7 5.9 5.9 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DDRGK PF09756.9 CDJ46372.1 - 5.2 6.6 17.9 0.24 11.0 12.0 1.6 2 0 0 2 2 2 0 DDRGK domain Spt20 PF12090.8 CDJ46372.1 - 5.4 6.6 29.8 9.3 5.8 29.8 1.2 1 0 0 1 1 1 0 Spt20 family Hid1 PF12722.7 CDJ46372.1 - 5.9 4.9 5.5 8.5 4.4 5.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SRP-alpha_N PF04086.13 CDJ46372.1 - 6.1 6.7 15.6 5.3 6.9 6.7 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Ank_5 PF13857.6 CDJ46374.1 - 2.8e-19 68.9 0.4 2.3e-12 46.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ46374.1 - 3.4e-14 53.0 2.2 6.1e-08 33.1 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ46374.1 - 5.9e-12 46.0 0.1 1.1e-11 45.1 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ46374.1 - 1.4e-11 44.3 0.3 5e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CDJ46374.1 - 1e-08 34.7 0.1 0.00084 19.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat PseudoU_synth_2 PF00849.22 CDJ46376.1 - 6.3e-24 84.9 0.0 1.8e-23 83.4 0.0 1.7 1 1 0 1 1 1 1 RNA pseudouridylate synthase Shugoshin_N PF07558.11 CDJ46377.1 - 0.065 13.1 2.0 0.16 11.9 2.0 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region GWT1 PF06423.12 CDJ46378.1 - 8.8e-15 55.1 3.2 8.8e-15 55.1 3.2 3.1 3 1 0 3 3 3 1 GWT1 H-kinase_dim PF02895.14 CDJ46380.1 - 0.066 13.6 0.6 3 8.3 0.0 2.8 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Diphthami_syn_2 PF01902.17 CDJ46381.1 - 4.8e-27 94.9 0.0 1.7e-24 86.5 0.0 2.6 1 1 1 2 2 2 2 Diphthamide synthase QueC PF06508.13 CDJ46381.1 - 0.034 13.6 0.1 0.081 12.4 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CDJ46381.1 - 0.062 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase AAA PF00004.29 CDJ46382.1 - 1.1e-38 132.7 0.0 2.3e-38 131.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 CDJ46382.1 - 2.1e-16 59.7 0.3 3.8e-16 58.9 0.3 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CDJ46382.1 - 4.2e-08 32.9 0.0 1.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CDJ46382.1 - 2.9e-06 27.2 0.6 9.2e-06 25.6 0.5 1.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CDJ46382.1 - 2.2e-05 24.3 0.0 6.3e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CDJ46382.1 - 0.00037 20.3 0.0 0.00071 19.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CDJ46382.1 - 0.0012 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CDJ46382.1 - 0.0019 18.4 0.0 0.0037 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CDJ46382.1 - 0.0033 17.8 0.6 14 6.0 0.0 3.3 2 1 1 3 3 3 0 AAA ATPase domain AAA_33 PF13671.6 CDJ46382.1 - 0.006 16.7 0.1 0.063 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CDJ46382.1 - 0.007 16.4 0.6 0.089 12.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ46382.1 - 0.0071 16.6 1.2 0.28 11.4 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CDJ46382.1 - 0.012 15.1 0.3 4.8 6.7 0.0 2.9 2 1 1 3 3 3 0 AAA domain TPR_12 PF13424.6 CDJ46382.1 - 0.031 14.6 0.4 0.16 12.3 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PSK_trans_fac PF07704.11 CDJ46382.1 - 0.17 12.7 1.0 7.7 7.3 0.0 3.0 3 0 0 3 3 2 0 Rv0623-like transcription factor DnaJ PF00226.31 CDJ46383.1 - 1.6e-18 66.6 7.3 3.1e-18 65.6 1.3 3.4 2 1 0 2 2 2 1 DnaJ domain IKKbetaNEMObind PF12179.8 CDJ46383.1 - 0.019 15.0 0.0 0.055 13.5 0.0 1.8 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain GYF PF02213.16 CDJ46384.1 - 1.9e-11 43.4 0.0 4.2e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CDJ46384.1 - 0.0038 17.0 0.0 0.017 15.0 0.0 2.2 1 0 0 1 1 1 1 GYF domain 2 Pkinase PF00069.25 CDJ46385.1 - 4.6e-16 59.0 0.0 1.5e-13 50.7 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Kinase-like PF14531.6 CDJ46385.1 - 2.9e-10 40.0 0.0 2.8e-09 36.7 0.0 2.2 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ46385.1 - 1.3e-07 31.2 0.0 6.1e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2722 PF10846.8 CDJ46385.1 - 0.00025 20.1 7.3 0.00035 19.7 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ46385.1 - 0.00052 20.1 7.0 0.0011 19.1 7.0 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ46385.1 - 0.011 16.4 3.1 0.011 16.4 3.1 1.6 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ46385.1 - 0.11 12.2 18.3 0.17 11.5 18.3 1.2 1 0 0 1 1 1 0 Spt20 family FTA2 PF13095.6 CDJ46385.1 - 0.2 11.3 1.6 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Presenilin PF01080.17 CDJ46385.1 - 0.23 10.2 3.3 0.32 9.7 3.3 1.2 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 CDJ46385.1 - 1.2 9.2 6.5 2.3 8.2 6.5 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4834 PF16118.5 CDJ46385.1 - 1.9 9.5 6.9 6.3 7.8 6.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ46385.1 - 2.7 7.9 8.1 4.3 7.2 8.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.10 CDJ46385.1 - 6.4 5.3 19.7 5.8 5.5 18.5 1.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MOZ_SAS PF01853.18 CDJ46386.1 - 9.9e-53 178.4 0.3 1.4e-36 125.8 0.5 2.2 1 1 1 2 2 2 2 MOZ/SAS family Tudor-knot PF11717.8 CDJ46386.1 - 1.5e-08 34.4 0.1 6.8e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain RskA PF10099.9 CDJ46386.1 - 2.3 8.5 26.1 0.097 13.0 15.6 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ46387.1 - 0.0065 16.1 14.0 0.0065 16.1 14.0 5.9 2 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ46387.1 - 1.8 8.8 46.5 0.019 15.3 21.3 3.8 1 1 2 3 3 3 0 Anti-sigma-K factor rskA Pkinase PF00069.25 CDJ46389.1 - 8.7e-14 51.5 0.9 1e-06 28.3 0.0 2.9 4 0 0 4 4 4 2 Protein kinase domain Kinase-like PF14531.6 CDJ46389.1 - 1.9e-09 37.2 8.7 3.2e-05 23.4 0.0 3.9 4 0 0 4 4 4 3 Kinase-like Pkinase_Tyr PF07714.17 CDJ46389.1 - 8.8e-06 25.2 0.1 0.0029 17.0 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase PNISR PF15996.5 CDJ46389.1 - 0.91 9.8 27.7 0.78 10.0 0.6 3.8 4 0 0 4 4 4 0 Arginine/serine-rich protein PNISR Pex14_N PF04695.13 CDJ46389.1 - 9.8 6.8 40.9 0.13 12.9 9.3 4.5 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MCM_OB PF17207.3 CDJ46390.1 - 4.3e-07 29.8 0.0 6.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 CDJ46390.1 - 0.011 16.3 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 MCM N-terminal domain RskA PF10099.9 CDJ46391.1 - 0.004 17.5 3.0 0.0056 17.0 3.0 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ46391.1 - 0.054 13.5 21.0 0.07 13.1 21.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PepSY_2 PF13670.6 CDJ46391.1 - 0.054 13.5 8.1 0.085 12.9 8.1 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain K_channel_TID PF07941.11 CDJ46391.1 - 0.11 13.0 9.9 0.27 11.7 9.9 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Plasmodium_Vir PF05795.11 CDJ46391.1 - 2.9 7.2 22.7 4.7 6.5 22.7 1.3 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Utp14 PF04615.13 CDJ46391.1 - 7.4 5.0 17.2 9.6 4.6 17.2 1.1 1 0 0 1 1 1 0 Utp14 protein MCM PF00493.23 CDJ46392.1 - 5.9e-79 264.3 0.0 7.3e-79 264.0 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CDJ46392.1 - 1.9e-14 53.8 0.1 3.7e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ46392.1 - 3.7e-06 26.5 0.0 7.8e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ46392.1 - 0.0054 16.6 0.0 0.0099 15.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ46392.1 - 0.0087 16.1 0.0 0.035 14.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CDJ46392.1 - 0.05 13.3 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DEAD PF00270.29 CDJ46392.1 - 0.1 12.4 0.0 3 7.6 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase CHAD PF05235.14 CDJ46392.1 - 0.21 11.5 2.7 0.99 9.3 2.7 2.2 1 1 0 1 1 1 0 CHAD domain Tim54 PF11711.8 CDJ46393.1 - 0.016 14.0 23.8 0.021 13.6 23.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2828 PF11443.8 CDJ46393.1 - 0.034 12.2 29.7 0.041 12.0 29.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3807 PF12720.7 CDJ46393.1 - 0.087 13.1 41.0 0.11 12.8 41.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) MDM10 PF12519.8 CDJ46393.1 - 0.1 11.4 27.7 0.12 11.2 27.7 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 NPR3 PF03666.13 CDJ46393.1 - 0.39 9.5 30.9 0.43 9.3 30.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 CDJ46393.1 - 0.4 10.4 38.7 0.49 10.2 38.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF966 PF06136.13 CDJ46393.1 - 0.51 10.0 27.2 0.59 9.8 27.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ALMT PF11744.8 CDJ46393.1 - 0.55 9.0 27.4 0.66 8.7 27.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter PCM1_C PF15717.5 CDJ46393.1 - 0.57 8.8 31.8 0.69 8.5 31.8 1.0 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Presenilin PF01080.17 CDJ46393.1 - 0.77 8.5 40.6 0.9 8.2 40.6 1.0 1 0 0 1 1 1 0 Presenilin Dsh_C PF12316.8 CDJ46393.1 - 0.79 10.1 16.1 0.88 9.9 16.1 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SLC12 PF03522.15 CDJ46393.1 - 0.87 8.5 35.6 0.99 8.4 35.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PNISR PF15996.5 CDJ46393.1 - 0.88 9.8 38.1 1 9.6 38.1 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF913 PF06025.12 CDJ46393.1 - 0.99 8.3 20.2 1.4 7.8 20.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 CDJ46393.1 - 1.2 7.0 32.1 1.3 6.8 32.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3295 PF11702.8 CDJ46393.1 - 1.2 8.4 29.4 1.4 8.2 29.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF4746 PF15928.5 CDJ46393.1 - 1.2 8.5 24.1 1.5 8.2 24.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4045 PF13254.6 CDJ46393.1 - 1.3 8.6 29.2 1.5 8.4 29.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.14 CDJ46393.1 - 1.3 7.2 32.4 1.5 7.0 32.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Draxin PF15550.6 CDJ46393.1 - 1.4 8.7 21.7 1.6 8.5 21.7 1.1 1 0 0 1 1 1 0 Draxin Lin-8 PF03353.15 CDJ46393.1 - 1.7 8.1 36.5 1.9 8.0 36.5 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PPL5 PF18168.1 CDJ46393.1 - 1.7 7.8 22.8 2.7 7.2 22.8 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Gti1_Pac2 PF09729.9 CDJ46393.1 - 1.9 8.5 29.3 2.5 8.1 29.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family CCSAP PF15748.5 CDJ46393.1 - 2 8.5 38.1 2.3 8.3 38.1 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Membralin PF09746.9 CDJ46393.1 - 2.2 7.2 23.2 2.5 7.1 23.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein PA26 PF04636.13 CDJ46393.1 - 2.5 6.9 25.4 2.9 6.7 25.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Bul1_C PF04426.12 CDJ46393.1 - 2.7 7.3 26.1 3.6 6.9 26.1 1.1 1 0 0 1 1 1 0 Bul1 C terminus DUF4776 PF16003.5 CDJ46393.1 - 2.8 6.8 30.5 3.1 6.7 30.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DDRGK PF09756.9 CDJ46393.1 - 3 7.4 48.4 3.7 7.1 48.4 1.1 1 0 0 1 1 1 0 DDRGK domain DUF2052 PF09747.9 CDJ46393.1 - 3 7.9 35.3 3.7 7.6 35.3 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2151 PF10221.9 CDJ46393.1 - 3.1 6.3 21.0 3.6 6.1 21.0 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator GAGA_bind PF06217.12 CDJ46393.1 - 3.4 7.9 29.9 3.9 7.7 29.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family WTX PF09422.10 CDJ46393.1 - 3.6 6.5 22.2 4 6.4 22.2 1.0 1 0 0 1 1 1 0 WTX protein Endostatin PF06482.11 CDJ46393.1 - 3.9 6.9 30.6 4.5 6.6 30.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PTPRCAP PF15713.5 CDJ46393.1 - 4.3 7.6 32.4 7.2 6.9 32.4 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Raftlin PF15250.6 CDJ46393.1 - 4.6 5.9 26.2 5.3 5.7 26.2 1.0 1 0 0 1 1 1 0 Raftlin Vfa1 PF08432.10 CDJ46393.1 - 4.8 7.5 36.8 6 7.2 36.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.16 CDJ46393.1 - 5.1 7.1 28.9 6.1 6.8 28.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.12 CDJ46393.1 - 5.2 6.3 34.3 6.5 6.0 34.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Band_3_cyto PF07565.13 CDJ46393.1 - 5.9 6.6 32.7 9.4 5.9 32.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CKAP2_C PF15297.6 CDJ46393.1 - 6.1 5.8 27.7 7.7 5.5 27.7 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus CSG2 PF16965.5 CDJ46393.1 - 6.2 5.7 20.3 8.3 5.2 20.3 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator AAA_11 PF13086.6 CDJ46393.1 - 6.7 6.4 34.9 7.8 6.2 34.9 1.0 1 0 0 1 1 1 0 AAA domain MCM_bind PF09739.9 CDJ46393.1 - 7 5.0 33.1 8.1 4.8 33.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor FAM60A PF15396.6 CDJ46393.1 - 7.5 6.5 30.1 9.1 6.2 30.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF572 PF04502.13 CDJ46393.1 - 7.5 6.1 31.8 9.4 5.8 31.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4050 PF13259.6 CDJ46393.1 - 7.6 6.8 28.1 10 6.4 28.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Hid1 PF12722.7 CDJ46393.1 - 8 4.5 32.1 8.2 4.4 32.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 CDJ46393.1 - 8 5.1 26.4 9.2 4.9 26.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UPF0565 PF10561.9 CDJ46393.1 - 8.2 5.5 19.1 9.6 5.3 19.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Velvet PF11754.8 CDJ46393.1 - 8.6 6.2 31.9 11 5.8 31.9 1.1 1 0 0 1 1 1 0 Velvet factor DUF2370 PF10176.9 CDJ46393.1 - 8.8 5.9 18.2 11 5.5 18.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) BORG_CEP PF14957.6 CDJ46393.1 - 9.4 7.4 23.8 13 7.0 23.8 1.2 1 0 0 1 1 1 0 Cdc42 effector SPG4 PF17325.2 CDJ46394.1 - 0.11 13.6 0.7 0.12 13.4 0.7 1.2 1 0 0 1 1 1 0 Stationary phase protein 4 SDA1 PF05285.12 CDJ46394.1 - 0.23 10.9 7.4 0.23 10.9 7.4 1.0 1 0 0 1 1 1 0 SDA1 Styelin PF17562.2 CDJ46394.1 - 0.55 10.6 5.9 0.35 11.3 3.6 1.8 2 0 0 2 2 2 0 Styelin HABP4_PAI-RBP1 PF04774.15 CDJ46394.1 - 1.1 10.2 8.1 1.3 9.9 8.1 1.1 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family FYDLN_acid PF09538.10 CDJ46394.1 - 1.7 9.4 7.9 2.1 9.1 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) ERp29 PF07749.12 CDJ46394.1 - 2.1 9.3 9.4 3.7 8.5 9.4 1.5 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Kei1 PF08552.11 CDJ46394.1 - 4.2 7.2 5.7 4.7 7.0 5.7 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Hamartin PF04388.12 CDJ46395.1 - 2.8 6.5 29.8 3.3 6.2 29.8 1.0 1 0 0 1 1 1 0 Hamartin protein tRNA-synt_2 PF00152.20 CDJ46396.1 - 5.2e-31 107.9 0.1 4.1e-30 104.9 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ46396.1 - 0.00011 22.1 0.0 0.015 15.3 0.0 2.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain GT87 PF09594.10 CDJ46396.1 - 0.0076 16.0 55.6 0.038 13.7 22.6 5.0 5 0 0 5 5 5 3 Glycosyltransferase family 87 RskA PF10099.9 CDJ46396.1 - 0.014 15.7 10.9 0.014 15.7 10.9 11.2 6 3 3 9 9 9 0 Anti-sigma-K factor rskA Bot1p PF12298.8 CDJ46397.1 - 0.019 15.1 5.3 0.021 15.0 5.3 1.0 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein TFIIA PF03153.13 CDJ46397.1 - 0.19 11.7 19.4 0.22 11.5 19.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 CDJ46397.1 - 0.48 10.7 7.5 0.48 10.7 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF3138 PF11336.8 CDJ46397.1 - 0.76 8.3 15.6 0.91 8.1 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DivIC PF04977.15 CDJ46397.1 - 0.79 9.5 9.9 1.1 9.1 9.9 1.3 1 0 0 1 1 1 0 Septum formation initiator UPF0560 PF10577.9 CDJ46397.1 - 1.2 7.6 8.5 1.2 7.5 8.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RLL PF10036.9 CDJ46397.1 - 1.2 8.9 11.2 1.5 8.6 11.2 1.0 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein FSA_C PF10479.9 CDJ46397.1 - 1.6 6.7 5.9 1.7 6.6 5.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3464 PF11947.8 CDJ46397.1 - 2.9 7.6 6.6 4.1 7.2 6.6 1.3 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 Macoilin PF09726.9 CDJ46397.1 - 3.2 6.2 10.8 3.9 5.9 10.8 1.2 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 CDJ46397.1 - 8.5 4.9 10.4 8.9 4.9 10.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RskA PF10099.9 CDJ46399.1 - 4.6 7.5 30.4 1.8e+04 -9.2 30.4 3.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Pkinase PF00069.25 CDJ46400.1 - 3.9e-13 49.4 0.0 3.9e-13 49.4 0.0 4.4 4 1 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ46400.1 - 4.8e-06 26.0 0.0 4.8e-06 26.0 0.0 3.3 4 1 0 4 4 4 1 Protein tyrosine kinase Med3 PF11593.8 CDJ46401.1 - 0.019 14.2 8.9 0.016 14.4 8.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4336 PF14234.6 CDJ46401.1 - 0.069 12.3 0.9 0.095 11.9 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Androgen_recep PF02166.16 CDJ46401.1 - 0.16 10.7 16.2 0.21 10.4 16.2 1.1 1 0 0 1 1 1 0 Androgen receptor DUF2967 PF11179.8 CDJ46401.1 - 0.41 8.7 8.7 0.37 8.8 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Presenilin PF01080.17 CDJ46401.1 - 0.99 8.1 6.2 1.1 7.9 6.2 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ46401.1 - 5.4 5.9 11.6 6.6 5.6 11.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med3 PF11593.8 CDJ46402.1 - 7.8 5.6 9.7 10 5.2 9.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MAR_sialic_bdg PF10564.9 CDJ46404.1 - 4.2e-43 145.3 23.6 2.2e-17 62.8 2.3 4.4 4 0 0 4 4 4 4 Sialic-acid binding micronemal adhesive repeat SR-25 PF10500.9 CDJ46404.1 - 0.003 17.2 11.8 0.0053 16.4 11.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ46404.1 - 0.17 12.6 11.3 0.62 10.8 11.3 2.0 1 0 0 1 1 1 0 Immortalisation up-regulated protein Secretin_N_2 PF07655.13 CDJ46404.1 - 0.51 10.9 13.0 1 9.9 13.0 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DUF3138 PF11336.8 CDJ46404.1 - 0.73 8.4 6.9 1.4 7.4 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4614 PF15391.6 CDJ46404.1 - 6.5 6.7 9.7 3.2 7.7 5.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) RAP1 PF07218.11 CDJ46404.1 - 7 4.8 8.9 9.3 4.4 8.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Roughex PF06020.11 CDJ46405.1 - 0.0021 17.2 8.0 0.0021 17.2 8.0 2.2 2 0 0 2 2 2 1 Drosophila roughex protein eIF-3_zeta PF05091.12 CDJ46405.1 - 0.78 8.6 14.4 0.095 11.7 4.9 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM176 PF14851.6 CDJ46405.1 - 1.5 8.5 6.2 1.4 8.6 0.6 2.2 2 0 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 CDJ46405.1 - 2.3 9.2 17.5 0.34 11.9 6.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4820 PF16091.5 CDJ46405.1 - 4.2 6.7 16.4 0.47 9.8 6.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Lin-8 PF03353.15 CDJ46405.1 - 5 6.6 20.2 0.41 10.2 7.8 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF1764 PF08576.10 CDJ46405.1 - 7 7.6 12.2 5.8 7.9 2.4 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF4834 PF16118.5 CDJ46407.1 - 2.2e-05 25.4 0.4 4e-05 24.5 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ46407.1 - 0.00015 20.9 13.9 0.00019 20.5 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ46407.1 - 0.0086 15.7 22.0 0.011 15.4 22.0 1.1 1 0 0 1 1 1 1 Spt20 family Pex14_N PF04695.13 CDJ46407.1 - 0.013 16.2 9.9 0.013 16.2 9.9 1.9 2 1 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.19 CDJ46407.1 - 0.017 13.1 0.8 0.021 12.8 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF-3_zeta PF05091.12 CDJ46407.1 - 0.018 14.0 10.5 0.022 13.8 10.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2828 PF11443.8 CDJ46407.1 - 0.018 13.1 0.7 0.021 12.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PigN PF04987.14 CDJ46407.1 - 0.033 13.1 0.3 0.062 12.2 0.3 1.4 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) SID-1_RNA_chan PF13965.6 CDJ46407.1 - 0.045 12.2 0.0 0.056 11.9 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIA PF03153.13 CDJ46407.1 - 0.056 13.4 20.7 0.072 13.1 20.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NARP1 PF12569.8 CDJ46407.1 - 0.084 11.8 5.4 0.1 11.5 5.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Med15 PF09606.10 CDJ46407.1 - 0.098 11.3 17.9 0.14 10.8 17.9 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.16 CDJ46407.1 - 0.15 12.1 0.3 0.18 11.8 0.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 CDJ46407.1 - 0.16 11.9 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 N-glycosylation protein SpoIIP PF07454.11 CDJ46407.1 - 0.2 11.1 4.5 0.23 10.9 4.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF702 PF05142.12 CDJ46407.1 - 0.22 12.0 9.4 0.33 11.4 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) NPR3 PF03666.13 CDJ46407.1 - 0.22 10.3 4.9 0.26 10.1 4.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 CDJ46407.1 - 0.36 10.6 2.4 0.49 10.1 2.4 1.2 1 0 0 1 1 1 0 Connexin tRNA_synt_1c_R2 PF04557.15 CDJ46407.1 - 0.39 11.7 5.3 0.7 10.9 5.3 1.3 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Suf PF05843.14 CDJ46407.1 - 0.83 9.6 11.0 1.1 9.2 11.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3306 PF11748.8 CDJ46407.1 - 0.86 10.5 12.7 1.8 9.5 12.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Ctr PF04145.15 CDJ46407.1 - 0.91 10.1 4.7 0.83 10.3 3.2 1.6 1 1 0 1 1 1 0 Ctr copper transporter family RR_TM4-6 PF06459.12 CDJ46407.1 - 1.1 9.0 6.4 1.5 8.6 6.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2368 PF10166.9 CDJ46407.1 - 1.3 8.6 9.5 3.1 7.4 9.5 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) TERB2 PF15101.6 CDJ46407.1 - 1.6 8.8 10.3 2.2 8.3 10.3 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4746 PF15928.5 CDJ46407.1 - 2.4 7.5 6.7 3.1 7.1 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) OATP PF03137.20 CDJ46407.1 - 2.9 6.1 4.8 0.79 7.9 1.3 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GTA_holin_3TM PF11351.8 CDJ46407.1 - 4.4 7.9 10.7 12 6.5 10.7 1.8 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release DDRGK PF09756.9 CDJ46407.1 - 4.8 6.7 16.4 6.6 6.3 16.4 1.1 1 0 0 1 1 1 0 DDRGK domain Coilin_N PF15862.5 CDJ46407.1 - 8.5 6.2 12.4 13 5.6 12.4 1.2 1 0 0 1 1 1 0 Coilin N-terminus AF-4 PF05110.13 CDJ46408.1 - 0.0039 15.4 27.3 0.0058 14.8 27.3 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein DUF677 PF05055.12 CDJ46408.1 - 0.03 13.2 2.8 0.042 12.7 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) SR-25 PF10500.9 CDJ46409.1 - 0.00018 21.2 8.5 0.00018 21.2 8.5 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ46409.1 - 0.0024 16.1 10.7 0.0024 16.1 10.7 1.6 2 0 0 2 2 2 1 AF-4 proto-oncoprotein Velvet PF11754.8 CDJ46409.1 - 0.0025 17.8 3.7 0.0043 17.0 3.7 1.4 1 0 0 1 1 1 1 Velvet factor Sporozoite_P67 PF05642.11 CDJ46409.1 - 0.024 12.7 1.8 0.035 12.2 1.8 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen AviRa PF11599.8 CDJ46409.1 - 0.21 11.0 2.7 0.39 10.1 2.7 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DUF1645 PF07816.11 CDJ46409.1 - 1.4 9.5 13.7 0.088 13.4 6.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1645) Neur_chan_memb PF02932.16 CDJ46409.1 - 3.7 7.6 5.2 1.5 8.8 1.4 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RAP1 PF07218.11 CDJ46409.1 - 6.1 5.0 5.0 12 4.0 5.0 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Coilin_N PF15862.5 CDJ46409.1 - 8.2 6.2 10.3 7.9 6.3 5.6 2.2 2 0 0 2 2 2 0 Coilin N-terminus SPX PF03105.19 CDJ46411.1 - 0.004 17.1 33.9 1.1 9.0 5.9 3.4 2 1 0 2 2 2 1 SPX domain Dehydrin PF00257.19 CDJ46411.1 - 0.0051 17.4 5.8 0.0051 17.4 5.8 10.1 6 4 3 9 9 9 1 Dehydrin RskA PF10099.9 CDJ46412.1 - 0.0025 18.2 7.2 0.0032 17.8 7.2 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ46412.1 - 0.018 14.6 11.0 0.018 14.7 11.0 1.2 1 0 0 1 1 1 0 Spt20 family DUF4179 PF13786.6 CDJ46412.1 - 0.035 14.6 0.9 0.055 14.0 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) TFIIA PF03153.13 CDJ46412.1 - 0.33 10.9 17.0 0.34 10.9 17.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit R_equi_Vir PF05526.11 CDJ46412.1 - 0.71 9.7 8.4 0.87 9.4 8.4 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Cwf_Cwc_15 PF04889.12 CDJ46413.1 - 0.3 10.8 0.0 0.14 11.8 14.6 6.6 5 1 0 5 5 5 0 Cwf15/Cwc15 cell cycle control protein DctQ PF04290.12 CDJ46414.1 - 0.33 10.9 3.6 0.16 11.9 1.1 1.7 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component NVEALA PF14055.6 CDJ46414.1 - 0.61 10.1 0.1 0.61 10.1 0.1 3.7 4 1 0 4 4 4 0 NVEALA protein MTS_N PF08468.11 CDJ46414.1 - 0.71 9.9 9.0 4.8 7.2 0.6 2.2 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal Na_trans_assoc PF06512.13 CDJ46416.1 - 0.96 9.7 19.8 1.6 8.9 7.4 2.6 2 0 0 2 2 2 0 Sodium ion transport-associated Pertus-S4-tox PF09275.10 CDJ46416.1 - 1.1 9.5 5.5 5.1 7.4 0.1 4.0 2 1 0 2 2 2 0 Pertussis toxin S4 subunit CAF1 PF04857.20 CDJ46416.1 - 7.9 5.5 13.2 0.8 8.8 2.8 2.4 2 0 0 2 2 2 0 CAF1 family ribonuclease SARAF PF06682.12 CDJ46417.1 - 0.00048 19.9 14.9 0.00048 19.9 14.9 12.9 9 2 4 13 13 13 1 SOCE-associated regulatory factor of calcium homoeostasis GT87 PF09594.10 CDJ46417.1 - 0.00094 19.0 0.2 0.00094 19.0 0.2 13.5 10 5 3 13 13 13 1 Glycosyltransferase family 87 DUF2722 PF10846.8 CDJ46417.1 - 0.0011 18.0 2.5 0.0011 18.0 2.5 14.2 11 3 3 14 14 14 4 Protein of unknown function (DUF2722) Macoilin PF09726.9 CDJ46417.1 - 0.0013 17.4 17.3 0.0013 17.4 17.3 11.2 8 3 2 10 10 10 1 Macoilin family DUF3597 PF12200.8 CDJ46417.1 - 0.23 12.0 0.0 0.23 12.0 0.0 17.9 14 4 3 17 17 17 0 Domain of unknown function (DUF3597) FAP PF07174.11 CDJ46418.1 - 0.38 10.2 50.9 0.48 9.8 50.9 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF2721 PF11026.8 CDJ46419.1 - 0.0041 17.0 2.5 0.11 12.4 3.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) FA_desaturase PF00487.24 CDJ46419.1 - 0.21 11.4 4.4 1.3 8.8 4.4 2.0 1 1 0 1 1 1 0 Fatty acid desaturase BAF1_ABF1 PF04684.13 CDJ46419.1 - 0.29 10.1 9.2 0.36 9.8 9.2 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.10 CDJ46419.1 - 0.45 9.1 25.1 0.73 8.4 25.1 1.3 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DOCK_N PF16172.5 CDJ46419.1 - 5.3 5.9 11.0 43 2.9 11.0 2.3 1 1 0 1 1 1 0 DOCK N-terminus Neur_chan_memb PF02932.16 CDJ46419.1 - 7.7 6.5 11.1 16 5.5 11.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NifW PF03206.14 CDJ46419.1 - 8.9 6.9 11.4 0.37 11.3 4.5 2.3 2 1 0 2 2 2 0 Nitrogen fixation protein NifW SURF6 PF04935.12 CDJ46422.1 - 1.4 8.6 29.1 0.72 9.6 17.2 2.3 2 0 0 2 2 2 0 Surfeit locus protein 6 Ndc1_Nup PF09531.10 CDJ46423.1 - 0.038 12.7 4.0 0.041 12.6 4.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.9 CDJ46423.1 - 0.085 12.5 17.8 0.12 11.9 17.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4536 PF15055.6 CDJ46423.1 - 0.3 11.3 3.6 0.79 10.0 2.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4536) Presenilin PF01080.17 CDJ46423.1 - 0.34 9.6 9.4 0.43 9.3 9.4 1.3 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 CDJ46423.1 - 6.2 5.5 12.4 7.9 5.2 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Dehydrin PF00257.19 CDJ46423.1 - 7.3 7.1 15.5 0.53 10.8 9.1 2.0 2 1 0 2 2 2 0 Dehydrin HSBP1 PF06825.12 CDJ46424.1 - 3.4e-12 46.0 0.1 5.1e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF4530 PF15039.6 CDJ46424.1 - 0.0021 18.2 0.2 0.0021 18.2 0.2 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4530) DUF2802 PF10975.8 CDJ46424.1 - 0.28 11.4 11.2 4.2 7.6 4.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DUF3886 PF13025.6 CDJ46424.1 - 4.5 7.5 14.2 0.59 10.4 6.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) DUF5345 PF17280.2 CDJ46424.1 - 6.8 6.8 6.9 28 4.8 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF2894 PF11445.8 CDJ46424.1 - 8.8 6.7 13.5 28 5.1 8.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) SUIM_assoc PF16619.5 CDJ46424.1 - 9.5 6.4 17.9 0.33 11.0 5.4 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Secretin_N_2 PF07655.13 CDJ46428.1 - 2.2 8.9 17.8 4.6 7.8 10.4 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain SPX PF03105.19 CDJ46428.1 - 2.8 7.8 11.6 3.3 7.5 11.6 1.2 1 0 0 1 1 1 0 SPX domain DUF3648 PF12364.8 CDJ46429.1 - 0.05 13.8 4.2 0.091 13.0 4.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3648) Ndc1_Nup PF09531.10 CDJ46429.1 - 2.4 6.8 7.7 2.8 6.5 7.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nop14 PF04147.12 CDJ46430.1 - 2e-09 36.3 63.4 2e-09 36.3 63.4 3.9 4 1 0 4 4 4 1 Nop14-like family Dus PF01207.17 CDJ46431.1 - 4.7e-08 32.5 19.6 0.00021 20.5 7.4 4.2 3 2 0 3 3 3 2 Dihydrouridine synthase (Dus) Sugar_tr PF00083.24 CDJ46432.1 - 7.9e-05 21.7 12.6 0.00024 20.1 12.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ46432.1 - 0.00014 20.9 10.0 0.00022 20.3 10.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3824 PF12868.7 CDJ46432.1 - 0.00097 19.8 4.6 0.0017 19.0 4.6 1.4 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) DUF2722 PF10846.8 CDJ46432.1 - 0.0046 16.0 16.8 0.006 15.6 16.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ46432.1 - 0.014 15.4 18.7 0.016 15.2 18.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ46432.1 - 0.017 13.8 17.1 0.02 13.6 17.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.13 CDJ46432.1 - 0.021 13.9 2.8 0.025 13.7 2.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GREB1 PF15782.5 CDJ46432.1 - 0.024 11.8 8.1 0.028 11.6 8.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CDJ46432.1 - 0.032 13.7 4.5 0.039 13.4 4.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Spt20 PF12090.8 CDJ46432.1 - 0.033 13.8 20.7 0.042 13.5 20.7 1.1 1 0 0 1 1 1 0 Spt20 family TPPK_C PF12555.8 CDJ46432.1 - 0.042 13.9 1.0 0.042 13.9 1.0 2.7 3 0 0 3 3 1 0 Thiamine pyrophosphokinase C terminal DUF4775 PF16001.5 CDJ46432.1 - 0.059 12.8 6.8 0.07 12.5 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) SpoIIP PF07454.11 CDJ46432.1 - 0.099 12.1 3.9 0.11 11.9 3.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Med3 PF11593.8 CDJ46432.1 - 0.1 11.8 17.0 0.15 11.3 17.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FHIPEP PF00771.20 CDJ46432.1 - 0.14 10.6 2.3 0.19 10.2 2.3 1.1 1 0 0 1 1 1 0 FHIPEP family TERB2 PF15101.6 CDJ46432.1 - 0.15 12.1 6.8 0.19 11.8 6.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF1645 PF07816.11 CDJ46432.1 - 0.16 12.5 11.9 0.22 12.1 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) CPSF100_C PF13299.6 CDJ46432.1 - 0.28 11.4 7.6 0.38 10.9 7.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Roughex PF06020.11 CDJ46432.1 - 0.34 10.0 7.8 0.4 9.7 7.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Dicty_REP PF05086.12 CDJ46432.1 - 0.49 8.3 3.2 0.6 8.0 3.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Presenilin PF01080.17 CDJ46432.1 - 0.53 9.0 7.4 0.81 8.4 7.4 1.3 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CDJ46432.1 - 0.77 9.7 12.0 0.97 9.4 12.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 CDJ46432.1 - 0.91 7.7 12.6 0.98 7.6 12.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.9 CDJ46432.1 - 0.96 8.2 6.6 1.1 8.0 6.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sporozoite_P67 PF05642.11 CDJ46432.1 - 1.1 7.3 7.8 1.6 6.8 7.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Miga PF10265.9 CDJ46432.1 - 1.3 7.9 6.0 1.7 7.5 6.0 1.1 1 0 0 1 1 1 0 Mitoguardin XRN_N PF03159.18 CDJ46432.1 - 1.4 8.3 5.2 1.7 8.0 5.2 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus UPF0560 PF10577.9 CDJ46432.1 - 1.5 7.3 9.7 1.8 6.9 9.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Lin-8 PF03353.15 CDJ46432.1 - 1.5 8.3 11.6 1.9 8.0 11.6 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist V_ATPase_I PF01496.19 CDJ46432.1 - 2 6.3 4.4 2.4 5.9 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AF-4 PF05110.13 CDJ46432.1 - 2.1 6.3 16.2 3 5.8 16.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Med24_N PF11277.8 CDJ46432.1 - 2.7 5.9 5.1 3.5 5.6 5.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Tim54 PF11711.8 CDJ46432.1 - 2.9 6.6 7.7 3.6 6.3 7.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RAP1 PF07218.11 CDJ46432.1 - 3.2 5.9 3.5 3.7 5.7 3.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S64 PF08192.11 CDJ46432.1 - 3.3 6.1 9.4 4.3 5.7 9.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.9 CDJ46432.1 - 3.4 6.1 8.9 4.6 5.7 8.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF4834 PF16118.5 CDJ46432.1 - 3.8 8.5 10.2 10 7.2 10.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2076 PF09849.9 CDJ46432.1 - 3.9 7.5 25.1 1.6 8.7 22.5 1.6 2 0 0 2 2 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FAM176 PF14851.6 CDJ46432.1 - 4.4 7.0 5.8 1.3 8.6 1.1 2.1 2 0 0 2 2 2 0 FAM176 family DUF4820 PF16091.5 CDJ46432.1 - 5.1 6.4 8.4 8.2 5.7 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3464 PF11947.8 CDJ46432.1 - 5.7 6.7 9.8 12 5.6 9.8 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 EIIBC-GUT_N PF03612.14 CDJ46432.1 - 6 6.6 7.5 9 6.0 7.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Baculo_PP31 PF05311.11 CDJ46432.1 - 7.4 6.0 9.9 10 5.5 9.9 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RskA PF10099.9 CDJ46432.1 - 8.8 6.6 24.8 6.9 6.9 16.5 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ46433.1 - 0.0031 17.8 3.1 0.0037 17.6 3.1 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ46433.1 - 1.7 9.3 18.6 3.3 8.4 18.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein RIFIN PF02009.16 CDJ46433.1 - 2.4 7.9 12.4 2.9 7.7 12.4 1.0 1 0 0 1 1 1 0 Rifin MMR_HSR1 PF01926.23 CDJ46434.1 - 9.9e-06 25.6 0.1 0.0003 20.8 0.1 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.6 CDJ46434.1 - 0.00027 21.6 0.2 0.025 15.2 0.0 3.1 2 1 0 2 2 2 1 GTP-binding GTPase N-terminal SR-25 PF10500.9 CDJ46434.1 - 0.0017 18.0 12.5 0.0017 18.0 12.5 12.0 6 1 5 12 12 12 4 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ46434.1 - 0.047 14.0 0.3 0.047 14.0 0.3 7.9 5 3 1 6 6 6 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ46435.1 - 0.0059 16.2 26.5 0.0059 16.2 26.5 12.9 9 3 1 10 10 10 3 Spt20 family RskA PF10099.9 CDJ46435.1 - 0.02 15.2 0.3 0.02 15.2 0.3 18.7 3 2 13 16 16 16 0 Anti-sigma-K factor rskA DHHC PF01529.20 CDJ46436.1 - 2e-33 115.3 1.2 2e-33 115.3 1.2 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase GPR15L PF15854.5 CDJ46436.1 - 0.0037 17.5 1.3 0.0037 17.5 1.3 2.4 2 0 0 2 2 2 1 G-protein coupled receptor ligand 15 Colicin_V PF02674.16 CDJ46436.1 - 1.4 8.9 16.0 2.4 8.1 6.0 2.4 2 0 0 2 2 2 0 Colicin V production protein START PF01852.19 CDJ46437.1 - 2.2e-05 23.9 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 START domain DUF4667 PF15700.5 CDJ46437.1 - 0.0033 17.6 0.1 0.0033 17.6 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) Ribosomal_60s PF00428.19 CDJ46437.1 - 0.0071 16.9 9.1 0.0071 16.9 9.1 7.1 3 2 1 4 4 4 2 60s Acidic ribosomal protein SR-25 PF10500.9 CDJ46437.1 - 0.42 10.2 16.6 0.98 9.0 16.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ46437.1 - 2.2 6.2 16.2 3.6 5.5 16.2 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2415 PF10313.9 CDJ46438.1 - 0.079 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) SPX PF03105.19 CDJ46438.1 - 0.36 10.7 13.3 1.6 8.5 11.1 2.2 2 1 0 2 2 2 0 SPX domain Sporozoite_P67 PF05642.11 CDJ46438.1 - 5.1 5.1 12.5 0.0071 14.5 0.4 2.2 2 1 0 2 2 2 0 Sporozoite P67 surface antigen TP_methylase PF00590.20 CDJ46439.1 - 3.8e-16 59.7 0.1 6.2e-16 59.0 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Bromo_TP_like PF17027.5 CDJ46439.1 - 0.12 12.6 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Histone-fold protein UQ_con PF00179.26 CDJ46440.1 - 1.8e-37 128.1 0.1 2.1e-37 127.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ46440.1 - 0.0003 20.5 0.0 0.00038 20.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ46440.1 - 0.01 16.1 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain APG5 PF04106.12 CDJ46441.1 - 7.2e-47 159.9 0.0 9.9e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 RskA PF10099.9 CDJ46442.1 - 0.03 14.6 8.7 0.041 14.2 8.7 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Roughex PF06020.11 CDJ46442.1 - 0.048 12.8 3.7 0.061 12.4 3.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein THOC2_N PF16134.5 CDJ46442.1 - 0.28 9.8 3.3 0.33 9.5 3.3 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus PGA2 PF07543.12 CDJ46442.1 - 4.1 7.4 13.7 10 6.1 13.7 1.6 1 1 0 1 1 1 0 Protein trafficking PGA2 ABC2_membrane_3 PF12698.7 CDJ46443.1 - 0.3 10.1 2.7 0.72 8.9 2.7 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3439 PF11921.8 CDJ46443.1 - 7.5 6.5 13.9 5.7 6.9 6.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Med15 PF09606.10 CDJ46444.1 - 2 7.0 20.4 2.5 6.7 20.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 CDJ46444.1 - 3.9 6.1 27.9 0.034 12.9 5.6 2.1 2 0 0 2 2 2 0 Presenilin Trp_oprn_chp PF09534.10 CDJ46444.1 - 7.7 6.3 47.2 1.6 8.5 11.0 2.7 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RXLR PF16810.5 CDJ46445.1 - 0.36 11.3 8.7 0.43 11.0 8.7 1.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity KOG2701 PF09762.9 CDJ46445.1 - 1.4 9.1 19.0 1.5 9.0 19.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) Auxin_canalis PF05703.11 CDJ46445.1 - 1.7 8.5 10.9 2.6 7.9 10.9 1.3 1 0 0 1 1 1 0 Auxin canalisation BPL_N PF09825.9 CDJ46445.1 - 2.1 7.3 7.5 2.2 7.3 7.5 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Stig1 PF04885.13 CDJ46445.1 - 2.7 8.5 11.0 3.3 8.2 11.0 1.0 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Spt20 PF12090.8 CDJ46445.1 - 5.1 6.6 40.3 6.4 6.3 40.3 1.1 1 0 0 1 1 1 0 Spt20 family HNOBA PF07701.14 CDJ46445.1 - 7.5 5.9 16.2 8.7 5.7 16.2 1.0 1 0 0 1 1 1 0 Heme NO binding associated RPA43_OB PF17875.1 CDJ46445.1 - 8.9 7.0 11.5 10 6.8 11.5 1.1 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I ECH_2 PF16113.5 CDJ46446.1 - 1.1e-21 77.8 0.6 4.3e-20 72.5 0.4 2.8 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase Presenilin PF01080.17 CDJ46446.1 - 0.038 12.8 0.4 0.036 12.8 0.4 1.3 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ46446.1 - 1.7 9.7 9.5 2.7 9.0 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4834 PF16118.5 CDJ46447.1 - 0.028 15.4 7.6 0.029 15.3 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Trp_oprn_chp PF09534.10 CDJ46447.1 - 0.038 13.8 18.6 0.057 13.2 18.6 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SID-1_RNA_chan PF13965.6 CDJ46447.1 - 0.054 11.9 0.6 0.068 11.6 0.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF677 PF05055.12 CDJ46447.1 - 0.081 11.8 4.2 0.095 11.6 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF3487 PF11990.8 CDJ46447.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) FAM199X PF15814.5 CDJ46447.1 - 0.57 9.2 9.7 0.8 8.7 9.7 1.3 1 0 0 1 1 1 0 Protein family FAM199X DnaJ-X PF14308.6 CDJ46447.1 - 0.63 9.4 8.5 0.058 12.8 3.5 1.7 2 0 0 2 2 2 0 X-domain of DnaJ-containing RskA PF10099.9 CDJ46447.1 - 0.82 9.9 42.5 3.8e+02 1.3 42.5 2.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Serinc PF03348.15 CDJ46447.1 - 0.99 8.3 4.0 1 8.2 4.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Glyco_hydro_9 PF00759.19 CDJ46447.1 - 1.1 8.6 9.7 1.4 8.3 9.7 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 DUF4100 PF13352.6 CDJ46447.1 - 1.7 8.4 10.2 0.31 10.8 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4100) DUF2892 PF11127.8 CDJ46447.1 - 3.9 7.6 8.4 6.1 7.0 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) R_equi_Vir PF05526.11 CDJ46447.1 - 5.2 6.9 15.6 0.73 9.7 11.9 1.5 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein FHIPEP PF00771.20 CDJ46447.1 - 7.6 4.9 15.9 1.4 7.3 12.3 1.5 1 1 1 2 2 2 0 FHIPEP family Zea_mays_MuDR PF05928.11 CDJ46447.1 - 7.7 6.1 11.5 9.2 5.8 11.5 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) DUF2722 PF10846.8 CDJ46447.1 - 8.4 5.2 33.1 1.4 7.8 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ46447.1 - 9.9 5.7 42.7 7.5 6.1 5.8 2.1 2 0 0 2 2 2 0 Spt20 family LRS4 PF10422.9 CDJ46448.1 - 0.0057 16.3 17.2 0.0057 16.3 17.2 2.1 2 0 0 2 2 2 1 Monopolin complex subunit LRS4 MPM1 PF17234.2 CDJ46448.1 - 2.1 8.6 11.2 8.8 6.6 11.2 2.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 7tm_7 PF08395.12 CDJ46448.1 - 2.8 7.0 4.4 5.4 6.1 4.4 1.4 1 0 0 1 1 1 0 7tm Chemosensory receptor SR-25 PF10500.9 CDJ46449.1 - 0.0076 15.9 22.7 0.0082 15.8 21.8 1.5 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ46449.1 - 0.12 10.4 17.6 0.16 10.0 17.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Spt20 PF12090.8 CDJ46449.1 - 0.2 11.3 13.3 0.23 11.1 13.3 1.2 1 0 0 1 1 1 0 Spt20 family Mitofilin PF09731.9 CDJ46449.1 - 0.71 8.6 19.7 0.82 8.4 19.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TerB_C PF15615.6 CDJ46449.1 - 1.1 9.6 9.4 1.5 9.1 9.4 1.3 1 0 0 1 1 1 0 TerB-C domain PI3K_1B_p101 PF10486.9 CDJ46449.1 - 1.4 6.6 7.0 1.5 6.5 7.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CCSAP PF15748.5 CDJ46449.1 - 2.2 8.4 16.6 2.9 8.0 16.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Dsh_C PF12316.8 CDJ46449.1 - 2.8 8.3 27.2 3.7 7.9 27.2 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RLL PF10036.9 CDJ46449.1 - 3 7.6 10.0 3.5 7.4 10.0 1.0 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Secretin_N_2 PF07655.13 CDJ46449.1 - 3.3 8.3 18.9 5.5 7.6 18.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Draxin PF15550.6 CDJ46449.1 - 4.1 7.2 8.4 4.9 6.9 8.4 1.0 1 0 0 1 1 1 0 Draxin DUF4813 PF16072.5 CDJ46449.1 - 5.7 6.5 34.9 7.7 6.1 34.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF966 PF06136.13 CDJ46449.1 - 8.2 6.0 15.4 9.7 5.8 15.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TFIIA PF03153.13 CDJ46449.1 - 9.3 6.1 18.0 13 5.6 18.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 CDJ46450.1 - 3.6 7.1 43.4 6 6.4 43.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.7 CDJ46450.1 - 3.7 5.5 50.3 4.5 5.3 50.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dehydrin PF00257.19 CDJ46452.1 - 0.0055 17.3 3.0 0.0055 17.3 3.0 2.7 2 1 0 2 2 2 1 Dehydrin SR-25 PF10500.9 CDJ46452.1 - 0.06 13.0 21.7 0.37 10.4 11.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4627 PF15425.6 CDJ46452.1 - 0.1 12.2 0.2 0.22 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4627) DUF5427 PF10310.9 CDJ46452.1 - 1.3 7.9 13.1 2.3 7.1 13.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) RNA_pol_Rpc4 PF05132.14 CDJ46452.1 - 3.9 7.9 10.2 3.3 8.1 3.0 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4228 PF14009.6 CDJ46452.1 - 8.8 6.7 14.5 8.2 6.8 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) LRR_6 PF13516.6 CDJ46453.1 - 4.8e-05 23.1 5.0 5.8 7.2 0.0 5.0 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 CDJ46453.1 - 0.00092 19.6 2.6 0.096 13.1 0.1 3.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) SR-25 PF10500.9 CDJ46453.1 - 0.0014 18.3 11.4 0.0014 18.3 11.4 10.1 8 2 2 10 10 10 2 Nuclear RNA-splicing-associated protein EDR1 PF14381.6 CDJ46453.1 - 0.024 14.4 0.5 0.087 12.5 0.0 2.2 2 1 1 3 3 3 0 Ethylene-responsive protein kinase Le-CTR1 LRR_1 PF00560.33 CDJ46453.1 - 0.3 11.8 7.7 72 4.5 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat zf-CCCH PF00642.24 CDJ46454.1 - 0.0075 16.2 3.3 0.0075 16.2 3.3 4.1 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TFIIA PF03153.13 CDJ46455.1 - 0.0082 16.2 25.1 0.0095 16.0 25.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Secretin_N_2 PF07655.13 CDJ46455.1 - 0.89 10.1 16.9 0.59 10.7 12.5 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Spt20 PF12090.8 CDJ46455.1 - 3.8 7.0 21.9 0.87 9.2 16.0 2.0 2 0 0 2 2 2 0 Spt20 family Hamartin PF04388.12 CDJ46455.1 - 7.7 5.0 22.1 9.6 4.7 22.1 1.2 1 0 0 1 1 1 0 Hamartin protein NPR1_interact PF15699.5 CDJ46455.1 - 8.9 7.0 11.2 0.7 10.5 5.3 2.0 2 0 0 2 2 2 0 NPR1 interacting DUF755 PF05501.11 CDJ46456.1 - 0.017 15.4 9.2 0.017 15.4 9.2 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF755) Apt1 PF10351.9 CDJ46456.1 - 2.2 7.1 28.5 0.047 12.5 16.5 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain cwf18 PF08315.12 CDJ46457.1 - 0.14 12.8 21.1 0.18 12.4 21.1 1.1 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Pex16 PF08610.10 CDJ46457.1 - 6.7 5.8 9.8 9.1 5.3 9.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) PAT1 PF09770.9 CDJ46458.1 - 3.5 5.8 50.0 2.2 6.4 25.0 2.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CENP-C_mid PF15620.6 CDJ46459.1 - 0.031 14.2 2.3 0.035 14.1 2.3 1.1 1 0 0 1 1 1 0 Centromere assembly component CENP-C middle DNMT3B-binding region Phage_lysis PF03245.13 CDJ46459.1 - 0.053 13.7 2.2 0.065 13.4 2.2 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein DPM3 PF08285.11 CDJ46459.1 - 0.16 12.2 3.2 2.6 8.3 1.4 2.1 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) MIF4G PF02854.19 CDJ46459.1 - 0.33 10.5 4.3 4 7.0 4.5 1.9 1 1 0 1 1 1 0 MIF4G domain Nas2_N PF18265.1 CDJ46459.1 - 1.8 8.5 5.1 0.85 9.6 1.1 2.0 1 1 1 2 2 2 0 Nas2 N_terminal domain Sugar_tr PF00083.24 CDJ46462.1 - 0.31 9.8 0.8 0.36 9.6 0.8 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Serinc PF03348.15 CDJ46462.1 - 0.58 9.0 8.3 0.63 8.9 8.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) NicO PF03824.16 CDJ46462.1 - 0.79 9.0 1.6 0.83 8.9 1.6 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein SelP_N PF04592.14 CDJ46462.1 - 1.4 8.3 23.7 0.097 12.1 19.1 1.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region eIF_4EBP PF05456.11 CDJ46462.1 - 1.5 8.7 15.0 0.17 11.9 10.6 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Gastrin PF00918.17 CDJ46462.1 - 1.6 9.7 15.3 0.28 12.2 11.4 1.6 1 1 0 1 1 1 0 Gastrin/cholecystokinin family CLN3 PF02487.17 CDJ46462.1 - 1.8 7.5 11.9 1.9 7.4 11.9 1.1 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 CDJ46462.1 - 3 6.5 20.0 3.5 6.3 20.0 1.1 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 CDJ46462.1 - 4.9 7.1 7.2 5.9 6.8 7.2 1.3 1 0 0 1 1 1 0 N-glycosylation protein FAM176 PF14851.6 CDJ46462.1 - 5.3 6.7 13.3 0.57 9.8 9.2 1.5 2 0 0 2 2 2 0 FAM176 family FAM163 PF15069.6 CDJ46462.1 - 6.3 7.2 11.7 9.4 6.7 11.7 1.3 1 0 0 1 1 1 0 FAM163 family Ureide_permease PF07168.11 CDJ46462.1 - 6.7 5.3 5.9 7.6 5.2 5.9 1.2 1 0 0 1 1 1 0 Ureide permease DDHD PF02862.17 CDJ46462.1 - 6.9 6.8 14.7 8.8 6.4 14.7 1.2 1 0 0 1 1 1 0 DDHD domain DUF2828 PF11443.8 CDJ46462.1 - 7.2 4.6 14.5 7.3 4.5 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Zip PF02535.22 CDJ46462.1 - 10 5.3 12.6 11 5.1 12.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 CDJ46463.1 - 0.0021 18.1 21.4 0.0023 18.0 21.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 CDJ46463.1 - 0.016 14.6 16.6 0.022 14.2 16.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 CDJ46463.1 - 0.15 10.6 7.6 0.23 10.0 7.6 1.3 1 0 0 1 1 1 0 Macoilin family Neur_chan_memb PF02932.16 CDJ46463.1 - 0.42 10.6 3.1 0.49 10.4 3.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ46463.1 - 0.44 10.3 9.8 0.55 10.0 9.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1980 PF09323.10 CDJ46463.1 - 1.9 8.4 6.8 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4241 PF14025.6 CDJ46463.1 - 2.8 8.2 6.5 3.8 7.7 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) DUF3450 PF11932.8 CDJ46463.1 - 3.4 6.9 23.9 5.4 6.2 23.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PAT1 PF09770.9 CDJ46463.1 - 3.9 5.6 18.0 4.8 5.3 18.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Paramyxo_ncap PF00973.19 CDJ46463.1 - 5.2 5.9 9.2 6.4 5.6 9.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3584 PF12128.8 CDJ46463.1 - 8.3 3.8 23.1 9.6 3.6 23.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SR-25 PF10500.9 CDJ46464.1 - 0.011 15.4 37.1 0.056 13.1 17.8 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ46464.1 - 0.41 11.4 25.2 0.62 10.8 5.4 2.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein PAP1 PF08601.10 CDJ46464.1 - 1.1 9.0 37.2 3.1 7.4 21.2 2.7 2 1 0 2 2 2 0 Transcription factor PAP1 DUF2543 PF10820.8 CDJ46464.1 - 1.8 8.8 6.4 3.9 7.7 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) Secretin_N_2 PF07655.13 CDJ46464.1 - 5.7 7.6 28.9 4.9 7.8 9.4 2.9 2 0 0 2 2 2 0 Secretin N-terminal domain Roughex PF06020.11 CDJ46465.1 - 0.62 9.1 4.2 0.7 8.9 4.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SPX PF03105.19 CDJ46467.1 - 0.17 11.7 30.5 0.21 11.5 30.5 1.0 1 0 0 1 1 1 0 SPX domain DUF572 PF04502.13 CDJ46467.1 - 0.18 11.4 17.9 0.23 11.0 17.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Lin-8 PF03353.15 CDJ46467.1 - 0.65 9.5 13.3 0.93 9.0 13.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ46467.1 - 1.3 7.8 24.7 1.6 7.5 24.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nab6_mRNP_bdg PF10567.9 CDJ46467.1 - 2.1 7.7 13.9 2.2 7.7 13.9 1.3 1 0 0 1 1 1 0 RNA-recognition motif Sec3_C PF09763.9 CDJ46467.1 - 3.7 5.8 8.8 4.2 5.6 8.8 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 SAPS PF04499.15 CDJ46467.1 - 5.7 5.6 12.7 7.8 5.2 12.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein IHABP4_N PF16174.5 CDJ46467.1 - 8 7.0 17.0 8.3 7.0 16.1 1.4 1 1 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF1682 PF07946.14 CDJ46468.1 - 0.022 14.0 14.6 0.023 13.9 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PAT1 PF09770.9 CDJ46468.1 - 0.11 10.8 27.1 0.096 10.9 27.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 CDJ46468.1 - 0.11 11.5 25.8 0.11 11.4 25.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TCP PF03634.13 CDJ46468.1 - 0.11 13.0 30.2 0.17 12.4 30.2 1.3 1 0 0 1 1 1 0 TCP family transcription factor AAA_23 PF13476.6 CDJ46468.1 - 0.21 12.1 19.5 0.24 11.9 19.5 1.2 1 0 0 1 1 1 0 AAA domain SprA-related PF12118.8 CDJ46468.1 - 0.38 9.9 47.9 0.44 9.6 47.9 1.1 1 0 0 1 1 1 0 SprA-related family BNIP2 PF12496.8 CDJ46468.1 - 0.38 11.2 14.6 0.49 10.8 14.6 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PRCC PF10253.9 CDJ46468.1 - 0.5 11.1 32.1 0.67 10.7 32.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MDM31_MDM32 PF08118.11 CDJ46468.1 - 0.79 8.3 10.6 0.82 8.3 10.6 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF2828 PF11443.8 CDJ46468.1 - 1.7 6.6 21.0 1.8 6.5 21.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NARP1 PF12569.8 CDJ46468.1 - 2.8 6.7 21.9 3.2 6.5 21.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MAP70 PF07058.11 CDJ46468.1 - 2.9 6.5 24.6 3.4 6.3 24.6 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 Peptidase_U57 PF05582.12 CDJ46468.1 - 5.6 6.1 16.2 7.7 5.7 16.2 1.3 1 0 0 1 1 1 0 YabG peptidase U57 DUF5423 PF17461.2 CDJ46468.1 - 7 5.4 32.4 8.9 5.0 32.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5423) DUF4407 PF14362.6 CDJ46468.1 - 7.8 5.8 22.5 8.9 5.6 22.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2722 PF10846.8 CDJ46469.1 - 0.00014 21.0 11.0 0.00016 20.8 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ46469.1 - 0.00016 21.4 15.6 0.00016 21.4 15.6 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ46469.1 - 0.0038 17.3 15.9 0.0039 17.2 15.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ46469.1 - 0.008 15.7 1.7 0.008 15.7 1.7 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DUF4366 PF14283.6 CDJ46469.1 - 0.027 14.5 1.4 0.027 14.5 1.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Ribosomal_60s PF00428.19 CDJ46469.1 - 0.028 15.0 6.2 0.028 15.0 6.2 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Presenilin PF01080.17 CDJ46469.1 - 0.033 13.0 4.0 0.032 13.0 4.0 1.1 1 0 0 1 1 1 0 Presenilin Orf78 PF06024.12 CDJ46469.1 - 0.036 14.4 4.8 0.06 13.6 4.8 1.3 1 0 0 1 1 1 0 Orf78 (ac78) RR_TM4-6 PF06459.12 CDJ46469.1 - 0.037 13.9 1.9 0.033 14.0 1.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 CDJ46469.1 - 0.041 13.5 0.3 0.048 13.3 0.3 1.3 1 0 0 1 1 1 0 FAM176 family Consortin_C PF15281.6 CDJ46469.1 - 0.054 13.5 0.2 0.066 13.2 0.2 1.1 1 0 0 1 1 1 0 Consortin C-terminus Peroxin-13_N PF04088.13 CDJ46469.1 - 0.073 13.3 3.1 0.13 12.6 3.1 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DDHD PF02862.17 CDJ46469.1 - 0.099 12.8 2.2 0.095 12.8 2.2 1.2 1 0 0 1 1 1 0 DDHD domain Glt_symporter PF03616.14 CDJ46469.1 - 0.11 11.1 1.5 0.15 10.7 1.5 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter OATP PF03137.20 CDJ46469.1 - 0.24 9.7 1.1 0.23 9.7 1.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ABC2_membrane_2 PF12679.7 CDJ46469.1 - 0.25 10.6 1.7 0.3 10.3 1.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RICTOR_N PF14664.6 CDJ46469.1 - 0.27 10.2 3.3 0.36 9.8 3.3 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Neur_chan_memb PF02932.16 CDJ46469.1 - 0.33 11.0 2.1 0.32 11.0 2.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 CDJ46469.1 - 0.34 11.9 9.6 0.57 11.2 9.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) OAD_gamma PF04277.13 CDJ46469.1 - 0.41 11.3 7.2 2.6 8.7 0.1 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Med15 PF09606.10 CDJ46469.1 - 0.59 8.8 20.8 0.59 8.7 20.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3464 PF11947.8 CDJ46469.1 - 0.64 9.8 8.2 0.95 9.2 8.2 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Connexin PF00029.19 CDJ46469.1 - 1.3 8.7 5.5 1.7 8.4 5.5 1.1 1 0 0 1 1 1 0 Connexin Peptidase_S49_N PF08496.10 CDJ46469.1 - 1.4 8.9 8.4 2.2 8.3 8.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ORC_WH_C PF18137.1 CDJ46469.1 - 2.5 8.2 9.4 4.2 7.4 9.4 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Sec62 PF03839.16 CDJ46469.1 - 4 6.9 6.1 5.7 6.4 6.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 V_ATPase_I PF01496.19 CDJ46469.1 - 5.8 4.7 9.1 6.6 4.5 9.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GNT-I PF03071.15 CDJ46469.1 - 5.9 5.5 6.6 7.7 5.1 6.6 1.0 1 0 0 1 1 1 0 GNT-I family EIIBC-GUT_N PF03612.14 CDJ46469.1 - 6.7 6.4 11.7 8.1 6.1 11.6 1.2 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Rpp20 PF12328.8 CDJ46469.1 - 6.7 6.7 9.4 9.7 6.2 9.4 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Folate_carrier PF01770.18 CDJ46469.1 - 8.3 5.0 6.4 12 4.5 6.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF2076 PF09849.9 CDJ46469.1 - 8.9 6.3 26.9 6.8 6.7 25.8 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Apt1 PF10351.9 CDJ46470.1 - 0.017 14.0 7.9 0.021 13.7 7.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HGWP PF03578.15 CDJ46470.1 - 0.27 10.8 0.1 0.27 10.8 0.1 2.5 2 0 0 2 2 2 0 HGWP repeat MecA PF05389.12 CDJ46471.1 - 0.021 14.5 13.8 0.024 14.3 13.8 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) SpoIIP PF07454.11 CDJ46471.1 - 0.033 13.7 17.3 0.039 13.4 17.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) MRP-S26 PF14943.6 CDJ46471.1 - 0.093 12.6 18.3 0.12 12.3 18.3 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 NARP1 PF12569.8 CDJ46471.1 - 0.1 11.5 16.7 0.12 11.3 16.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4628 PF15429.6 CDJ46471.1 - 0.12 12.1 13.4 0.13 11.9 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Peptidase_S49_N PF08496.10 CDJ46471.1 - 0.13 12.3 17.3 0.16 12.1 17.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pex14_N PF04695.13 CDJ46471.1 - 0.14 12.8 24.5 0.17 12.6 24.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peroxin-13_N PF04088.13 CDJ46471.1 - 0.16 12.3 7.6 0.19 12.0 7.6 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region eIF-3_zeta PF05091.12 CDJ46471.1 - 0.18 10.8 20.9 0.19 10.7 20.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2448 PF10476.9 CDJ46471.1 - 0.24 11.2 8.3 0.32 10.9 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) CAML PF14963.6 CDJ46471.1 - 0.31 11.1 6.4 0.34 11.0 6.4 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Connexin PF00029.19 CDJ46471.1 - 0.35 10.6 11.5 0.39 10.5 11.5 1.2 1 0 0 1 1 1 0 Connexin GNAT_acetyltr_2 PF13718.6 CDJ46471.1 - 0.38 10.1 12.5 0.43 9.9 12.5 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Presenilin PF01080.17 CDJ46471.1 - 0.39 9.4 19.1 0.4 9.4 19.1 1.0 1 0 0 1 1 1 0 Presenilin DUF763 PF05559.11 CDJ46471.1 - 0.42 9.7 8.8 0.48 9.6 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF763) FAM176 PF14851.6 CDJ46471.1 - 0.43 10.2 8.4 0.48 10.1 8.4 1.2 1 0 0 1 1 1 0 FAM176 family DDHD PF02862.17 CDJ46471.1 - 0.48 10.6 14.8 0.51 10.5 14.8 1.1 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.6 CDJ46471.1 - 0.54 10.4 12.4 0.62 10.2 12.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Baculo_PP31 PF05311.11 CDJ46471.1 - 0.55 9.7 14.1 0.63 9.5 14.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF4471 PF14740.6 CDJ46471.1 - 0.6 9.3 13.4 0.64 9.2 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) PPL5 PF18168.1 CDJ46471.1 - 0.63 9.3 10.8 0.69 9.2 10.8 1.1 1 0 0 1 1 1 0 Prim-pol family 5 RR_TM4-6 PF06459.12 CDJ46471.1 - 0.68 9.7 17.1 0.73 9.6 17.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 CDJ46471.1 - 0.76 9.9 18.5 0.83 9.8 18.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated V_ATPase_I PF01496.19 CDJ46471.1 - 0.79 7.6 17.7 0.89 7.4 17.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Suf PF05843.14 CDJ46471.1 - 0.82 9.6 21.8 1.2 9.1 21.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Tim54 PF11711.8 CDJ46471.1 - 0.88 8.3 13.7 0.96 8.2 13.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.13 CDJ46471.1 - 0.91 9.5 47.2 1 9.3 47.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TT_ORF1 PF02956.14 CDJ46471.1 - 1.2 7.7 14.5 1.2 7.7 14.5 1.0 1 0 0 1 1 1 0 TT viral orf 1 DUF3408 PF11888.8 CDJ46471.1 - 1.3 9.2 18.4 1.7 8.8 18.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF3464 PF11947.8 CDJ46471.1 - 1.3 8.8 17.3 1.5 8.5 17.3 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TFB6 PF17110.5 CDJ46471.1 - 1.4 8.7 9.1 1.6 8.4 9.1 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4746 PF15928.5 CDJ46471.1 - 1.5 8.2 11.8 1.6 8.1 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1764 PF08576.10 CDJ46471.1 - 1.6 9.7 15.3 2.1 9.3 15.3 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Gti1_Pac2 PF09729.9 CDJ46471.1 - 1.6 8.8 13.4 1.9 8.6 13.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family FAM60A PF15396.6 CDJ46471.1 - 1.7 8.6 14.6 1.9 8.4 14.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Ctr PF04145.15 CDJ46471.1 - 1.7 9.2 9.7 1.9 9.1 9.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF2126 PF09899.9 CDJ46471.1 - 1.7 6.6 13.3 1.9 6.5 13.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SLC12 PF03522.15 CDJ46471.1 - 1.8 7.5 18.7 1.9 7.4 18.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 EOS1 PF12326.8 CDJ46471.1 - 1.8 8.5 7.8 2 8.3 7.8 1.2 1 0 0 1 1 1 0 N-glycosylation protein Hydin_ADK PF17213.3 CDJ46471.1 - 2 8.6 15.7 2.3 8.4 15.7 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF2828 PF11443.8 CDJ46471.1 - 2.1 6.3 16.8 2.4 6.2 16.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Pal1 PF08316.11 CDJ46471.1 - 2.3 9.0 7.5 2.8 8.7 7.5 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein EPL1 PF10513.9 CDJ46471.1 - 2.4 8.5 17.8 3.2 8.1 17.8 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Folate_carrier PF01770.18 CDJ46471.1 - 2.4 6.8 9.1 2.6 6.7 9.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier CTU2 PF10288.9 CDJ46471.1 - 2.7 8.3 17.1 3.3 8.0 17.1 1.3 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Sec62 PF03839.16 CDJ46471.1 - 2.8 7.4 13.7 3.1 7.2 13.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CLN3 PF02487.17 CDJ46471.1 - 2.9 6.8 13.5 3.1 6.7 13.5 1.1 1 0 0 1 1 1 0 CLN3 protein PIG-S PF10510.9 CDJ46471.1 - 3.1 6.5 19.0 3.4 6.4 19.0 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF3276 PF11680.8 CDJ46471.1 - 3.2 7.9 12.9 4.1 7.5 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Folliculin PF11704.8 CDJ46471.1 - 3.3 7.6 14.3 3.9 7.3 14.3 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport MDM31_MDM32 PF08118.11 CDJ46471.1 - 3.4 6.2 16.4 3.9 6.0 16.4 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins ALMT PF11744.8 CDJ46471.1 - 3.4 6.4 14.0 3.5 6.4 14.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Exonuc_VII_L PF02601.15 CDJ46471.1 - 3.5 7.1 24.3 3.5 7.1 24.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit MMU163 PF17119.5 CDJ46471.1 - 3.6 6.7 9.0 4.1 6.5 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Helicase_RecD PF05127.14 CDJ46471.1 - 3.6 7.4 9.5 4 7.3 9.5 1.1 1 0 0 1 1 1 0 Helicase HemX PF04375.14 CDJ46471.1 - 3.7 6.8 41.8 3.9 6.7 41.8 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase OmpH PF03938.14 CDJ46471.1 - 3.7 7.9 45.0 5.3 7.4 45.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Band_3_cyto PF07565.13 CDJ46471.1 - 4.1 7.1 17.6 4.8 6.9 17.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Het-C PF07217.11 CDJ46471.1 - 4.3 5.8 15.1 4.4 5.7 15.1 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Peptidase_U57 PF05582.12 CDJ46471.1 - 4.3 6.5 13.5 5.1 6.3 13.5 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Mgr1 PF08602.10 CDJ46471.1 - 4.5 6.0 14.0 5.3 5.8 14.0 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Ureide_permease PF07168.11 CDJ46471.1 - 4.7 5.9 8.6 4.9 5.8 8.6 1.1 1 0 0 1 1 1 0 Ureide permease Nup88 PF10168.9 CDJ46471.1 - 4.7 4.9 24.7 5 4.8 24.7 1.0 1 0 0 1 1 1 0 Nuclear pore component Neur_chan_memb PF02932.16 CDJ46471.1 - 5.5 7.0 16.7 6.1 6.8 16.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2347 PF09804.9 CDJ46471.1 - 5.6 6.5 13.2 6.9 6.2 13.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Spore_coat_CotO PF14153.6 CDJ46471.1 - 5.6 6.8 27.4 6.8 6.6 27.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CSG2 PF16965.5 CDJ46471.1 - 5.7 5.8 10.2 5.9 5.7 10.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Paf1 PF03985.13 CDJ46471.1 - 5.7 5.8 21.2 6.5 5.6 21.2 1.1 1 0 0 1 1 1 0 Paf1 PAT1 PF09770.9 CDJ46471.1 - 5.9 5.0 31.9 6.1 5.0 31.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S15 PF02129.18 CDJ46471.1 - 6.5 6.3 12.9 7.5 6.1 12.9 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Membralin PF09746.9 CDJ46471.1 - 6.6 5.7 13.3 7.1 5.6 13.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF1980 PF09323.10 CDJ46471.1 - 6.6 6.6 12.0 8.7 6.2 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SID-1_RNA_chan PF13965.6 CDJ46471.1 - 6.7 5.0 10.9 7.3 4.9 10.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 YABBY PF04690.13 CDJ46471.1 - 6.8 7.2 15.0 7.9 7.0 15.0 1.2 1 0 0 1 1 1 0 YABBY protein MMR1 PF08505.10 CDJ46471.1 - 6.9 6.9 22.5 7.6 6.7 22.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Serinc PF03348.15 CDJ46471.1 - 7.4 5.4 13.5 8.8 5.1 13.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ndc1_Nup PF09531.10 CDJ46471.1 - 7.6 5.1 13.7 7.7 5.1 13.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup F-protein PF00469.20 CDJ46471.1 - 8.4 5.9 17.2 9.8 5.7 17.2 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Mem_trans PF03547.18 CDJ46471.1 - 9.4 4.5 5.7 9.2 4.5 5.7 1.0 1 0 0 1 1 1 0 Membrane transport protein MDM10 PF12519.8 CDJ46471.1 - 9.8 4.9 14.8 10 4.8 14.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 GTP_EFTU PF00009.27 CDJ46472.1 - 2.6e-66 222.9 0.1 3.9e-66 222.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CDJ46472.1 - 5.2e-31 106.9 0.0 4.7e-30 103.8 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CDJ46472.1 - 4e-19 68.4 0.0 8.8e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CDJ46472.1 - 8.8e-15 54.6 0.0 2.3e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CDJ46472.1 - 9.2e-12 45.2 0.1 2.1e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ46472.1 - 5.6e-05 23.2 0.1 0.00012 22.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 CDJ46472.1 - 0.022 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 CDJ46472.1 - 0.083 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Shikimate_DH PF01488.20 CDJ46472.1 - 0.085 12.9 0.0 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Myosin_head PF00063.21 CDJ46473.1 - 4.8e-181 603.4 0.1 5.6e-181 603.2 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CDJ46473.1 - 0.012 16.1 0.0 0.034 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 CDJ46473.1 - 0.023 14.4 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 CDJ46473.1 - 0.035 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CDJ46473.1 - 0.041 14.1 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 CDJ46473.1 - 0.077 13.1 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_6 PF12774.7 CDJ46473.1 - 0.09 11.7 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 CDJ46473.1 - 0.093 13.1 0.0 0.47 10.9 0.0 2.2 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 CDJ46473.1 - 0.15 12.6 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RskA PF10099.9 CDJ46474.1 - 0.00075 19.8 10.9 0.00081 19.7 10.9 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Shadoo PF14999.6 CDJ46474.1 - 0.0013 18.8 2.6 0.0015 18.6 2.6 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Spt20 PF12090.8 CDJ46474.1 - 0.0089 15.7 25.1 0.0089 15.7 25.1 1.1 1 0 0 1 1 1 1 Spt20 family DUF4834 PF16118.5 CDJ46474.1 - 0.014 16.3 7.6 0.015 16.2 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Ribosomal_60s PF00428.19 CDJ46474.1 - 0.053 14.1 9.2 0.053 14.1 9.2 1.5 2 0 0 2 2 1 0 60s Acidic ribosomal protein Connexin PF00029.19 CDJ46474.1 - 0.17 11.6 4.1 0.17 11.6 4.1 1.0 1 0 0 1 1 1 0 Connexin Med15 PF09606.10 CDJ46474.1 - 0.17 10.5 22.6 0.16 10.7 22.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal R_equi_Vir PF05526.11 CDJ46474.1 - 0.27 11.1 7.7 0.29 11.0 7.7 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Ctr PF04145.15 CDJ46474.1 - 0.29 11.7 4.2 0.32 11.6 4.2 1.0 1 0 0 1 1 1 0 Ctr copper transporter family FHIPEP PF00771.20 CDJ46474.1 - 0.3 9.5 5.4 0.34 9.3 5.4 1.0 1 0 0 1 1 1 0 FHIPEP family RPA43_OB PF17875.1 CDJ46474.1 - 0.48 11.1 9.2 0.56 10.8 9.2 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF1980 PF09323.10 CDJ46474.1 - 0.58 10.1 4.1 0.62 10.0 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) TERB2 PF15101.6 CDJ46474.1 - 0.9 9.5 12.7 0.89 9.6 12.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Suf PF05843.14 CDJ46474.1 - 0.92 9.4 12.6 0.91 9.4 12.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 CDJ46474.1 - 0.95 8.4 12.9 0.97 8.3 12.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Roughex PF06020.11 CDJ46474.1 - 1.4 8.0 12.0 1.3 8.1 12.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Coilin_N PF15862.5 CDJ46474.1 - 1.4 8.7 10.9 1.6 8.6 10.9 1.2 1 0 0 1 1 1 0 Coilin N-terminus Zip PF02535.22 CDJ46474.1 - 1.5 7.9 5.1 1.6 7.8 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CSG2 PF16965.5 CDJ46474.1 - 1.6 7.6 4.2 1.5 7.7 4.2 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator EOS1 PF12326.8 CDJ46474.1 - 1.6 8.6 4.3 1.7 8.6 4.3 1.1 1 0 0 1 1 1 0 N-glycosylation protein TFIIA PF03153.13 CDJ46474.1 - 1.6 8.6 28.2 1.8 8.5 28.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.13 CDJ46474.1 - 2.1 8.1 8.1 2.3 7.9 8.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PigN PF04987.14 CDJ46474.1 - 2.4 6.9 3.1 2.5 6.9 3.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) SprA-related PF12118.8 CDJ46474.1 - 2.5 7.2 24.2 2.9 6.9 24.2 1.1 1 0 0 1 1 1 0 SprA-related family MMU163 PF17119.5 CDJ46474.1 - 2.5 7.2 6.5 2.7 7.1 6.5 1.0 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Presenilin PF01080.17 CDJ46474.1 - 2.8 6.6 14.0 3.3 6.4 14.0 1.0 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ46474.1 - 2.9 6.7 31.7 3.5 6.4 31.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Neur_chan_memb PF02932.16 CDJ46474.1 - 2.9 7.9 6.6 2.9 7.9 6.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 CDJ46474.1 - 3.6 7.7 10.8 3.8 7.6 10.8 1.1 1 0 0 1 1 1 0 DDHD domain CLN3 PF02487.17 CDJ46474.1 - 5 6.0 5.4 5 6.1 5.4 1.1 1 0 0 1 1 1 0 CLN3 protein DivIC PF04977.15 CDJ46474.1 - 6.1 6.7 17.0 10 6.0 17.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 CDJ46474.1 - 7.1 5.9 16.5 8.7 5.6 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Serinc PF03348.15 CDJ46474.1 - 7.9 5.3 6.3 8.5 5.2 6.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) RskA PF10099.9 CDJ46475.1 - 0.0044 17.4 5.0 0.0044 17.4 5.0 8.7 3 1 0 3 3 3 1 Anti-sigma-K factor rskA TRAP_alpha PF03896.16 CDJ46477.1 - 0.022 14.0 5.1 0.023 13.9 5.1 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CSG2 PF16965.5 CDJ46477.1 - 0.043 12.8 8.1 0.046 12.7 8.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Presenilin PF01080.17 CDJ46477.1 - 0.068 11.9 20.5 0.08 11.7 20.5 1.1 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 CDJ46477.1 - 0.13 10.3 17.6 0.15 10.2 17.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ctr PF04145.15 CDJ46477.1 - 0.19 12.4 11.8 0.26 11.9 11.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Connexin PF00029.19 CDJ46477.1 - 0.22 11.3 12.7 0.25 11.1 12.7 1.2 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 CDJ46477.1 - 0.22 9.9 8.0 0.24 9.7 8.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PA26 PF04636.13 CDJ46477.1 - 0.23 10.3 12.8 0.25 10.2 12.8 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PIP5K PF01504.18 CDJ46477.1 - 0.3 10.3 13.0 0.33 10.2 13.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Zip PF02535.22 CDJ46477.1 - 0.32 10.2 7.9 0.32 10.2 7.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Kei1 PF08552.11 CDJ46477.1 - 0.32 10.9 13.0 0.39 10.6 13.0 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Velvet PF11754.8 CDJ46477.1 - 0.37 10.7 16.3 0.42 10.5 16.3 1.0 1 0 0 1 1 1 0 Velvet factor Gti1_Pac2 PF09729.9 CDJ46477.1 - 0.38 10.8 15.2 0.43 10.6 15.2 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family CLN3 PF02487.17 CDJ46477.1 - 0.4 9.7 12.7 0.4 9.7 12.7 1.0 1 0 0 1 1 1 0 CLN3 protein DDHD PF02862.17 CDJ46477.1 - 0.42 10.7 16.4 0.58 10.3 16.4 1.2 1 0 0 1 1 1 0 DDHD domain SpoIIP PF07454.11 CDJ46477.1 - 0.45 9.9 18.5 0.54 9.7 18.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) V_ATPase_I PF01496.19 CDJ46477.1 - 0.47 8.3 19.0 0.52 8.2 19.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Serinc PF03348.15 CDJ46477.1 - 0.56 9.1 11.0 0.61 9.0 11.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) EOS1 PF12326.8 CDJ46477.1 - 0.59 10.0 12.4 0.66 9.9 12.4 1.1 1 0 0 1 1 1 0 N-glycosylation protein PPL5 PF18168.1 CDJ46477.1 - 0.76 9.0 13.1 0.93 8.7 13.1 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DAG_kinase_N PF14513.6 CDJ46477.1 - 0.8 9.9 16.6 0.84 9.8 16.6 1.0 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Folliculin PF11704.8 CDJ46477.1 - 0.82 9.5 16.1 1 9.2 16.1 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Tim54 PF11711.8 CDJ46477.1 - 0.9 8.2 17.1 1 8.0 17.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Afi1 PF07792.12 CDJ46477.1 - 0.91 10.0 13.8 1.3 9.5 13.8 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RNA_pol_Rpc4 PF05132.14 CDJ46477.1 - 1.1 9.7 16.5 1.4 9.3 16.5 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4569 PF15133.6 CDJ46477.1 - 1.1 8.9 18.6 1.2 8.8 18.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Fer4_22 PF17179.4 CDJ46477.1 - 1.2 10.0 14.5 1.4 9.8 14.5 1.0 1 0 0 1 1 1 0 4Fe-4S dicluster domain CCDC53 PF10152.9 CDJ46477.1 - 1.5 9.2 20.5 2 8.8 20.5 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CobT PF06213.12 CDJ46477.1 - 1.6 8.0 26.0 2 7.8 26.0 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sec62 PF03839.16 CDJ46477.1 - 1.7 8.1 16.6 1.8 8.0 16.6 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 CBP_BcsG PF11658.8 CDJ46477.1 - 2 6.8 14.6 2.1 6.6 14.6 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF3504 PF12012.8 CDJ46477.1 - 2 8.3 14.4 2.4 8.1 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Rtf2 PF04641.12 CDJ46477.1 - 2.2 7.6 22.9 2.5 7.4 22.9 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Folate_carrier PF01770.18 CDJ46477.1 - 2.5 6.8 9.5 3.2 6.4 9.5 1.2 1 0 0 1 1 1 0 Reduced folate carrier MDM10 PF12519.8 CDJ46477.1 - 2.6 6.8 16.5 2.9 6.7 16.5 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF913 PF06025.12 CDJ46477.1 - 2.6 6.9 13.7 3 6.7 13.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 CDJ46477.1 - 2.7 7.3 13.3 3.1 7.1 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MAJIN PF15077.6 CDJ46477.1 - 3 7.6 15.7 3.6 7.3 15.7 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Baculo_PP31 PF05311.11 CDJ46477.1 - 3.2 7.2 20.0 4 6.8 20.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Dicty_REP PF05086.12 CDJ46477.1 - 3.2 5.6 12.0 3.3 5.6 12.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4228 PF14009.6 CDJ46477.1 - 3.5 8.0 13.1 4.1 7.8 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Pinin_SDK_memA PF04696.13 CDJ46477.1 - 3.6 7.7 35.7 5 7.2 35.7 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Saw1 PF11561.8 CDJ46477.1 - 4.4 6.8 12.1 5.2 6.5 12.1 1.0 1 0 0 1 1 1 0 Single strand annealing-weakened 1 FAM60A PF15396.6 CDJ46477.1 - 4.5 7.2 18.3 5.5 6.9 18.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ46477.1 - 4.5 7.0 24.6 5.4 6.8 24.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CAF1 PF04857.20 CDJ46477.1 - 4.9 6.2 14.1 5.3 6.1 14.1 1.0 1 0 0 1 1 1 0 CAF1 family ribonuclease REC114-like PF15165.6 CDJ46477.1 - 5.3 6.8 25.1 6.7 6.4 25.1 1.0 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like UPF0565 PF10561.9 CDJ46477.1 - 6.1 6.0 13.9 7.3 5.7 13.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Otopetrin PF03189.13 CDJ46477.1 - 6.1 5.5 14.6 6.3 5.5 14.6 1.0 1 0 0 1 1 1 0 Otopetrin API5 PF05918.11 CDJ46477.1 - 6.1 5.5 19.2 6.3 5.5 19.2 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF5427 PF10310.9 CDJ46477.1 - 6.7 5.5 24.7 8 5.3 24.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Neur_chan_memb PF02932.16 CDJ46477.1 - 6.7 6.7 17.3 7.7 6.5 17.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ureide_permease PF07168.11 CDJ46477.1 - 7.9 5.1 10.4 9.1 4.9 10.4 1.1 1 0 0 1 1 1 0 Ureide permease DUF2464 PF10240.9 CDJ46477.1 - 8.1 5.9 14.4 8.9 5.8 14.4 1.0 1 0 0 1 1 1 0 Multivesicular body subunit 12 DUF2072 PF09845.9 CDJ46477.1 - 8.5 6.6 14.2 11 6.3 14.2 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein MMU163 PF17119.5 CDJ46477.1 - 8.8 5.4 10.4 12 5.0 10.4 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF5308 PF17233.2 CDJ46477.1 - 9.5 6.4 18.5 13 5.9 18.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) SpoIIP PF07454.11 CDJ46478.1 - 0.66 9.4 16.6 0.71 9.3 16.6 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CDJ46478.1 - 0.73 8.5 16.3 0.78 8.4 16.3 1.0 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CDJ46478.1 - 0.92 8.8 19.3 0.96 8.7 19.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spt20 PF12090.8 CDJ46478.1 - 1.1 8.9 39.1 1.5 8.3 39.1 1.3 1 0 0 1 1 1 0 Spt20 family DDHD PF02862.17 CDJ46478.1 - 3.1 7.9 12.5 2.9 8.0 12.5 1.0 1 0 0 1 1 1 0 DDHD domain GNAT_acetyltr_2 PF13718.6 CDJ46478.1 - 4 6.8 11.4 4.6 6.6 11.4 1.0 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF3332 PF11810.8 CDJ46478.1 - 6 6.5 8.7 8.7 6.0 8.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3332) CSG2 PF16965.5 CDJ46478.1 - 6.8 5.5 7.4 6.5 5.6 7.4 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator V_ATPase_I PF01496.19 CDJ46478.1 - 6.9 4.4 17.2 7.5 4.3 17.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2828 PF11443.8 CDJ46478.1 - 8.2 4.4 14.2 7.8 4.5 14.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Serinc PF03348.15 CDJ46478.1 - 9.5 5.0 11.7 9.2 5.1 11.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Connexin PF00029.19 CDJ46478.1 - 9.6 5.9 12.4 10 5.8 12.4 1.1 1 0 0 1 1 1 0 Connexin GatB_Yqey PF02637.18 CDJ46479.1 - 0.0001 22.2 0.1 0.00018 21.4 0.1 1.4 1 0 0 1 1 1 1 GatB domain DUF4456 PF14644.6 CDJ46479.1 - 0.025 14.3 1.8 0.036 13.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) VEFS-Box PF09733.9 CDJ46479.1 - 0.08 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein Prominin PF05478.11 CDJ46479.1 - 0.16 9.9 0.6 0.23 9.4 0.6 1.2 1 0 0 1 1 1 0 Prominin DUF4064 PF13273.6 CDJ46480.1 - 8.4 6.7 0.0 8.4 6.7 0.0 5.0 5 2 0 5 5 5 0 Protein of unknown function (DUF4064) KAsynt_C_assoc PF16197.5 CDJ46481.1 - 0.023 15.1 2.0 0.025 15.0 2.0 1.1 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Pex14_N PF04695.13 CDJ46481.1 - 5.6 7.6 19.1 6.3 7.4 19.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MAJIN PF15077.6 CDJ46481.1 - 6.4 6.5 9.8 6.7 6.4 9.8 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF3708 PF12501.8 CDJ46481.1 - 6.6 6.5 7.3 7.3 6.4 7.3 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Peptidase_S15 PF02129.18 CDJ46481.1 - 7.1 6.1 12.1 7.5 6.0 12.1 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CCDC24 PF15669.5 CDJ46483.1 - 3.8 7.3 6.5 4 7.3 6.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Corona_nucleoca PF00937.18 CDJ46483.1 - 5.1 6.0 11.4 4.6 6.2 11.4 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Sporozoite_P67 PF05642.11 CDJ46483.1 - 5.7 4.9 16.4 6.2 4.8 16.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apt1 PF10351.9 CDJ46483.1 - 7.5 5.3 7.6 7.9 5.2 7.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain RSRP PF17069.5 CDJ46483.1 - 8 5.9 25.3 8.6 5.8 25.3 1.0 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 DUF4614 PF15391.6 CDJ46483.1 - 9.1 6.2 10.8 10 6.1 10.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Zw10 PF06248.13 CDJ46484.1 - 0.91 8.0 15.6 0.25 9.8 6.2 3.3 4 0 0 4 4 4 0 Centromere/kinetochore Zw10 DUF572 PF04502.13 CDJ46485.1 - 3 7.4 30.7 3.6 7.1 30.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3371 PF11851.8 CDJ46485.1 - 7 7.8 34.9 0.57 11.3 10.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) RT_RNaseH PF17917.1 CDJ46488.1 - 3.6e-27 94.7 0.0 7.5e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ46488.1 - 1e-26 92.9 0.1 2.2e-26 91.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ46488.1 - 0.00011 22.0 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Smac_DIABLO PF09057.10 CDJ46488.1 - 0.076 12.4 0.1 8.4 5.7 0.0 2.4 2 0 0 2 2 2 0 Second Mitochondria-derived Activator of Caspases MORN PF02493.20 CDJ46489.1 - 2.2e-28 96.4 31.8 4.1e-08 32.6 1.8 5.1 5 0 0 5 5 5 4 MORN repeat Tudor_2 PF18104.1 CDJ46489.1 - 0.17 11.6 7.3 2.8 7.7 0.1 3.5 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain PPR_3 PF13812.6 CDJ46490.1 - 5.6e-40 135.2 0.0 5.6e-11 42.3 0.0 6.3 4 2 2 6 6 6 6 Pentatricopeptide repeat domain PPR_2 PF13041.6 CDJ46490.1 - 1.4e-38 130.9 0.0 1.3e-11 44.5 0.3 6.4 3 2 3 6 6 6 6 PPR repeat family PPR_long PF17177.4 CDJ46490.1 - 2.4e-26 92.4 16.7 1.5e-09 37.6 0.1 6.2 3 1 3 6 6 6 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CDJ46490.1 - 4.2e-19 67.4 0.1 0.00015 21.8 0.1 8.2 9 0 0 9 9 9 5 PPR repeat PPR_1 PF12854.7 CDJ46490.1 - 5.2e-14 51.6 0.0 0.87 9.3 0.0 6.9 7 0 0 7 7 7 5 PPR repeat SOG2 PF10428.9 CDJ46490.1 - 0.0004 19.7 19.4 0.0004 19.7 19.4 2.9 2 1 0 2 2 2 1 RAM signalling pathway protein SAPS PF04499.15 CDJ46490.1 - 0.035 12.9 21.1 0.59 8.9 13.6 2.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Zip PF02535.22 CDJ46490.1 - 0.74 9.0 23.9 2.3 7.3 14.2 2.6 2 0 0 2 2 2 0 ZIP Zinc transporter TFIIA PF03153.13 CDJ46491.1 - 0.94 9.4 14.1 1.1 9.2 14.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CRISPR_assoc PF08798.11 CDJ46491.1 - 1.6 8.8 8.9 0.071 13.2 0.6 2.0 1 1 1 2 2 2 0 CRISPR associated protein YlqD PF11068.8 CDJ46491.1 - 3.8 7.9 14.8 0.95 9.8 7.6 2.3 2 0 0 2 2 2 0 YlqD protein GREB1 PF15782.5 CDJ46491.1 - 4.1 4.4 11.1 4.7 4.2 11.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GAGA_bind PF06217.12 CDJ46491.1 - 5.4 7.2 10.5 7.1 6.8 10.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FSA_C PF10479.9 CDJ46491.1 - 6.3 4.8 7.0 7.8 4.5 7.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FAM199X PF15814.5 CDJ46491.1 - 9 5.2 11.1 4.8 6.2 9.1 1.5 1 1 0 1 1 1 0 Protein family FAM199X Orf78 PF06024.12 CDJ46494.1 - 0.021 15.1 0.3 0.021 15.1 0.3 2.5 2 1 0 2 2 2 0 Orf78 (ac78) Neur_chan_memb PF02932.16 CDJ46494.1 - 0.045 13.8 0.4 0.045 13.8 0.4 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4457 PF14652.6 CDJ46494.1 - 0.12 11.6 2.0 0.17 11.1 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) DUF1980 PF09323.10 CDJ46494.1 - 0.18 11.7 2.1 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Spt20 PF12090.8 CDJ46496.1 - 8.4e-05 22.3 25.3 8.4e-05 22.3 25.3 3.3 3 0 0 3 3 3 2 Spt20 family RskA PF10099.9 CDJ46496.1 - 0.0041 17.4 7.6 0.0041 17.4 7.6 4.7 2 1 3 5 5 4 2 Anti-sigma-K factor rskA Tim54 PF11711.8 CDJ46496.1 - 0.0061 15.4 2.3 0.0061 15.4 2.3 2.1 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 CDJ46496.1 - 0.0067 15.9 5.9 0.0067 15.9 5.9 2.3 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 CDJ46496.1 - 0.024 13.7 10.5 0.014 14.4 5.9 2.1 2 0 0 2 2 2 0 Solute carrier family 12 DUF4179 PF13786.6 CDJ46496.1 - 0.088 13.3 15.9 16 6.0 0.0 5.0 3 3 0 3 3 2 0 Domain of unknown function (DUF4179) eIF-3_zeta PF05091.12 CDJ46496.1 - 0.19 10.7 18.9 0.028 13.4 9.8 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIIBC-GUT_N PF03612.14 CDJ46496.1 - 0.29 10.8 13.8 0.021 14.6 4.5 2.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Connexin PF00029.19 CDJ46496.1 - 0.3 10.8 8.7 0.052 13.3 3.5 2.0 2 0 0 2 2 2 0 Connexin EOS1 PF12326.8 CDJ46496.1 - 0.65 9.9 12.3 0.092 12.7 4.2 2.3 2 1 0 2 2 2 0 N-glycosylation protein SID-1_RNA_chan PF13965.6 CDJ46496.1 - 0.93 7.8 7.2 0.35 9.2 4.1 1.7 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 CSG2 PF16965.5 CDJ46496.1 - 1.1 8.2 7.5 0.19 10.7 3.5 1.7 2 0 0 2 2 2 0 Ceramide synthase regulator FAM91_C PF14648.6 CDJ46496.1 - 1.5 7.5 8.2 0.036 12.9 1.6 1.7 2 0 0 2 2 2 0 FAM91 C-terminus zinc_ribbon_16 PF17034.5 CDJ46496.1 - 2.1 8.6 8.6 1.9 8.7 6.0 2.1 2 0 0 2 2 2 0 Zinc-ribbon like family DUF2072 PF09845.9 CDJ46496.1 - 5.5 7.3 10.1 1.3 9.3 4.5 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein Pannexin_like PF12534.8 CDJ46496.1 - 5.7 5.9 12.5 0.43 9.6 6.2 2.1 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 PIP5K PF01504.18 CDJ46496.1 - 5.9 6.0 14.5 2.6 7.2 9.3 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Sec62 PF03839.16 CDJ46496.1 - 6.8 6.1 10.3 0.59 9.6 3.9 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 XRCC4 PF06632.12 CDJ46496.1 - 8.1 5.2 17.3 0.2 10.5 9.5 2.1 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 CLN3 PF02487.17 CDJ46496.1 - 9.2 5.2 16.0 0.99 8.4 10.1 2.1 2 1 0 2 2 2 0 CLN3 protein Otopetrin PF03189.13 CDJ46496.1 - 9.9 4.9 16.0 16 4.2 16.0 1.6 1 1 0 1 1 1 0 Otopetrin XPG_I PF00867.18 CDJ46497.1 - 0.2 12.1 0.1 0.2 12.1 0.1 4.8 2 2 1 3 3 3 0 XPG I-region Trp_oprn_chp PF09534.10 CDJ46498.1 - 0.36 10.6 9.7 0.38 10.5 9.7 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RskA PF10099.9 CDJ46498.1 - 1.3 9.3 20.7 1.4 9.2 20.7 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 CDJ46498.1 - 6.4 5.7 17.6 6.7 5.6 17.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Shadoo PF14999.6 CDJ46499.1 - 0.47 10.6 21.1 0.82 9.8 7.7 2.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective TRAP_alpha PF03896.16 CDJ46500.1 - 0.0031 16.8 4.9 0.0038 16.5 4.9 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit CLN3 PF02487.17 CDJ46500.1 - 0.0035 16.5 7.8 0.004 16.3 7.8 1.2 1 0 0 1 1 1 1 CLN3 protein V_ATPase_I PF01496.19 CDJ46500.1 - 0.0053 14.8 16.2 0.0066 14.4 16.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 CDJ46500.1 - 0.011 14.2 2.9 0.013 14.0 2.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MMM1 PF10296.9 CDJ46500.1 - 0.017 14.2 4.6 0.023 13.8 4.6 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Zip PF02535.22 CDJ46500.1 - 0.041 13.1 7.0 0.05 12.8 7.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter O-antigen_lig PF13425.6 CDJ46500.1 - 0.067 12.0 3.2 0.082 11.7 3.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein TFIIA PF03153.13 CDJ46500.1 - 0.077 13.0 43.0 0.095 12.7 43.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Folate_carrier PF01770.18 CDJ46500.1 - 0.079 11.7 4.6 0.12 11.0 4.6 1.3 1 0 0 1 1 1 0 Reduced folate carrier Presenilin PF01080.17 CDJ46500.1 - 0.1 11.3 19.0 0.12 11.1 19.0 1.1 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 CDJ46500.1 - 0.14 11.1 4.5 0.17 10.7 4.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Velvet PF11754.8 CDJ46500.1 - 0.15 12.0 12.1 0.17 11.8 12.1 1.1 1 0 0 1 1 1 0 Velvet factor CBP_BcsG PF11658.8 CDJ46500.1 - 0.18 10.2 10.3 0.24 9.7 10.3 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Mem_trans PF03547.18 CDJ46500.1 - 0.26 9.7 5.1 0.31 9.4 5.1 1.1 1 0 0 1 1 1 0 Membrane transport protein Neur_chan_memb PF02932.16 CDJ46500.1 - 0.27 11.3 14.1 0.32 11.0 14.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cwf_Cwc_15 PF04889.12 CDJ46500.1 - 0.33 10.6 22.2 0.44 10.3 22.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SIT PF15330.6 CDJ46500.1 - 0.38 11.2 20.3 0.66 10.4 20.3 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT SLC12 PF03522.15 CDJ46500.1 - 0.4 9.6 17.4 0.46 9.4 17.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF2828 PF11443.8 CDJ46500.1 - 0.46 8.5 17.5 0.58 8.2 17.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CSG2 PF16965.5 CDJ46500.1 - 0.54 9.1 6.6 0.7 8.8 6.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator NEMP PF10225.9 CDJ46500.1 - 0.64 9.6 6.1 0.82 9.3 6.1 1.2 1 0 0 1 1 1 0 NEMP family Pex14_N PF04695.13 CDJ46500.1 - 0.73 10.5 23.5 1.2 9.8 23.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1180 PF06679.12 CDJ46500.1 - 0.78 10.1 14.7 2.9 8.3 14.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) SpoIIP PF07454.11 CDJ46500.1 - 0.82 9.1 14.9 1.2 8.6 14.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Peptidase_S49_N PF08496.10 CDJ46500.1 - 0.97 9.5 18.2 1.8 8.6 17.7 1.6 1 1 0 1 1 1 0 Peptidase family S49 N-terminal BAF1_ABF1 PF04684.13 CDJ46500.1 - 1.2 8.2 19.2 1.5 7.8 19.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FliP PF00813.20 CDJ46500.1 - 1.3 8.9 5.4 1.7 8.4 5.4 1.3 1 0 0 1 1 1 0 FliP family DUF3292 PF11696.8 CDJ46500.1 - 1.4 7.2 15.3 1.6 7.0 15.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Membralin PF09746.9 CDJ46500.1 - 1.8 7.5 9.4 2.1 7.3 9.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein BORG_CEP PF14957.6 CDJ46500.1 - 1.9 9.6 11.1 2.8 9.1 11.1 1.4 1 0 0 1 1 1 0 Cdc42 effector DUF2052 PF09747.9 CDJ46500.1 - 2.2 8.4 21.9 2.9 8.0 21.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.17 CDJ46500.1 - 2.6 8.1 14.0 3.7 7.6 14.0 1.3 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ46500.1 - 5 6.0 24.1 6 5.7 24.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4446 PF14584.6 CDJ46500.1 - 5.6 6.9 13.2 9.3 6.2 12.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) HemX PF04375.14 CDJ46500.1 - 7.2 5.8 39.0 8.9 5.5 39.0 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase HCO3_cotransp PF00955.21 CDJ46500.1 - 7.6 5.2 7.4 9.4 4.9 7.4 1.1 1 0 0 1 1 1 0 HCO3- transporter family Cyto_heme_lyase PF01265.17 CDJ46500.1 - 7.8 6.0 16.6 10 5.6 16.6 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase GREB1 PF15782.5 CDJ46500.1 - 7.9 3.5 19.7 9.4 3.2 19.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Band_3_cyto PF07565.13 CDJ46500.1 - 8 6.2 20.6 10 5.8 20.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ALMT PF11744.8 CDJ46500.1 - 8.2 5.1 16.5 10 4.8 16.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Endostatin PF06482.11 CDJ46500.1 - 8.5 5.7 18.4 10 5.5 18.4 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Ndc1_Nup PF09531.10 CDJ46500.1 - 8.9 4.9 12.3 10 4.7 12.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2347 PF09804.9 CDJ46500.1 - 9.3 5.7 14.4 12 5.4 14.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) CTU2 PF10288.9 CDJ46501.1 - 0.019 15.2 7.7 1.4 9.2 0.5 3.3 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF2052 PF09747.9 CDJ46501.1 - 0.095 12.8 0.1 0.095 12.8 0.1 2.9 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF3273 PF11677.8 CDJ46503.1 - 3e-78 262.8 8.1 2.7e-48 164.6 8.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3273) Dynein_light PF01221.18 CDJ46504.1 - 3.4e-25 88.2 0.0 4.6e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 MAS20 PF02064.15 CDJ46505.1 - 0.66 10.1 4.2 0.91 9.6 3.6 1.4 1 1 0 1 1 1 0 MAS20 protein import receptor Wbp11 PF09429.10 CDJ46506.1 - 9.1e-17 61.2 10.7 9.1e-17 61.2 10.7 2.4 2 0 0 2 2 2 1 WW domain binding protein 11 EBP50_C PF09007.11 CDJ46506.1 - 0.024 15.6 4.7 0.024 15.6 4.7 3.1 3 0 0 3 3 3 0 EBP50, C-terminal Alpha-2-MRAP_C PF06401.11 CDJ46506.1 - 0.028 14.4 2.0 0.068 13.1 2.0 1.6 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF789 PF05623.12 CDJ46506.1 - 1.9 8.1 5.4 0.28 10.8 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF789) Cation_ATPase_C PF00689.21 CDJ46508.1 - 4.6 6.9 10.3 6.7 6.4 10.3 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus RabGAP-TBC PF00566.18 CDJ46509.1 - 1.7e-45 155.3 5.2 2.1e-45 155.0 0.0 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Spt20 PF12090.8 CDJ46509.1 - 0.025 14.2 37.4 0.39 10.3 1.8 3.4 3 0 0 3 3 3 0 Spt20 family CPSF100_C PF13299.6 CDJ46509.1 - 0.9 9.7 4.9 1 9.6 1.8 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Peroxin-13_N PF04088.13 CDJ46509.1 - 2.9 8.2 6.8 0.78 10.0 1.8 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region PAT1 PF09770.9 CDJ46510.1 - 0.44 8.7 57.2 0.56 8.4 57.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.6 CDJ46510.1 - 0.9 10.0 33.3 1.6 9.2 33.3 1.4 1 0 0 1 1 1 0 AAA domain LicD PF04991.13 CDJ46510.1 - 2.5 8.2 11.5 3.3 7.8 11.5 1.2 1 0 0 1 1 1 0 LicD family MIIP PF15734.5 CDJ46512.1 - 0.44 10.0 10.1 0.42 10.0 10.1 1.0 1 0 0 1 1 1 0 Migration and invasion-inhibitory YjbH PF06082.11 CDJ46512.1 - 0.75 8.5 9.7 0.8 8.4 9.7 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Myb_DNA-binding PF00249.31 CDJ46513.1 - 0.00049 20.2 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain TFIIA PF03153.13 CDJ46513.1 - 0.1 12.6 83.3 0.025 14.6 55.8 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF726 PF05277.12 CDJ46513.1 - 6.3 5.6 9.2 9.2 5.1 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) TFIIA PF03153.13 CDJ46514.1 - 0.0087 16.1 23.6 0.0091 16.0 23.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF775 PF05603.12 CDJ46514.1 - 0.027 14.0 10.2 0.03 13.8 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF913 PF06025.12 CDJ46514.1 - 0.03 13.3 4.6 0.037 13.0 4.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SPATIAL PF15256.6 CDJ46514.1 - 0.036 14.4 8.9 0.044 14.1 8.9 1.1 1 0 0 1 1 1 0 SPATIAL MMU163 PF17119.5 CDJ46514.1 - 0.048 12.8 7.9 0.061 12.5 7.9 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Spt20 PF12090.8 CDJ46514.1 - 0.057 13.0 31.2 0.069 12.7 31.2 1.2 1 0 0 1 1 1 0 Spt20 family DUF868 PF05910.12 CDJ46514.1 - 0.068 12.8 4.5 0.086 12.5 4.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) Terminase_4 PF05119.12 CDJ46514.1 - 0.075 13.5 5.8 0.12 12.8 5.8 1.3 1 0 0 1 1 1 0 Phage terminase, small subunit Suf PF05843.14 CDJ46514.1 - 0.08 12.9 15.3 0.087 12.8 15.3 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BORG_CEP PF14957.6 CDJ46514.1 - 0.086 14.0 8.7 0.098 13.8 8.7 1.1 1 0 0 1 1 1 0 Cdc42 effector EOS1 PF12326.8 CDJ46514.1 - 0.1 12.5 2.0 0.12 12.3 2.0 1.2 1 0 0 1 1 1 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ46514.1 - 0.26 10.2 15.2 0.28 10.1 15.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hydin_ADK PF17213.3 CDJ46514.1 - 0.55 10.5 9.2 0.64 10.3 9.2 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Jak1_Phl PF17887.1 CDJ46514.1 - 0.57 10.1 10.2 0.72 9.8 10.2 1.2 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain eIF3_subunit PF08597.10 CDJ46514.1 - 0.78 9.6 13.3 0.97 9.3 13.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Folate_carrier PF01770.18 CDJ46514.1 - 0.84 8.3 2.6 0.79 8.4 2.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier Pex14_N PF04695.13 CDJ46514.1 - 0.89 10.2 19.2 1.2 9.8 19.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 CDJ46514.1 - 2.6 8.0 19.2 3.8 7.5 19.2 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 VIR_N PF15912.5 CDJ46514.1 - 2.8 7.5 10.6 3.3 7.2 10.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal RR_TM4-6 PF06459.12 CDJ46514.1 - 2.9 7.7 16.0 3.4 7.4 16.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.15 CDJ46514.1 - 3.1 6.6 4.5 3 6.7 4.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SpoIIP PF07454.11 CDJ46514.1 - 3.4 7.0 12.1 4.2 6.7 12.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Spore_coat_CotO PF14153.6 CDJ46514.1 - 3.6 7.5 20.2 4.3 7.2 20.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO ALMT PF11744.8 CDJ46514.1 - 3.7 6.3 6.8 3.5 6.4 6.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.6 CDJ46514.1 - 3.8 6.8 11.6 4.5 6.5 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sporozoite_P67 PF05642.11 CDJ46514.1 - 3.9 5.5 8.9 4.2 5.3 8.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tim54 PF11711.8 CDJ46514.1 - 4 6.1 14.0 5.2 5.8 14.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3292 PF11696.8 CDJ46514.1 - 4.2 5.6 13.0 5.1 5.3 13.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Band_3_cyto PF07565.13 CDJ46514.1 - 4.5 7.0 10.4 5.2 6.8 10.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Activator_LAG-3 PF11498.8 CDJ46514.1 - 4.8 6.0 39.7 6.1 5.7 39.7 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Neur_chan_memb PF02932.16 CDJ46514.1 - 5.7 6.9 11.1 6.3 6.8 11.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ46514.1 - 5.7 5.6 17.8 6.2 5.5 17.8 1.0 1 0 0 1 1 1 0 Presenilin MAJIN PF15077.6 CDJ46514.1 - 6.8 6.4 10.5 10 5.8 10.5 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein PAT1 PF09770.9 CDJ46514.1 - 7.5 4.7 21.2 9.1 4.4 21.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.6 CDJ46514.1 - 8 4.2 25.8 8.8 4.1 25.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Connexin PF00029.19 CDJ46514.1 - 9.4 5.9 8.8 12 5.6 8.8 1.2 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 CDJ46514.1 - 9.9 4.3 13.5 11 4.2 13.5 1.0 1 0 0 1 1 1 0 CDC45-like protein CRAL_TRIO PF00650.20 CDJ46515.1 - 9.5e-24 83.9 0.0 1.7e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CDJ46515.1 - 0.00088 19.4 3.1 0.0024 18.0 3.1 1.8 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CDJ46515.1 - 0.0071 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UB2H PF14814.6 CDJ46515.1 - 0.055 13.5 1.0 0.64 10.1 0.0 2.7 4 0 0 4 4 4 0 Bifunctional transglycosylase second domain Activator_LAG-3 PF11498.8 CDJ46516.1 - 0.0023 17.0 24.7 0.0023 17.0 24.7 6.2 6 0 0 6 6 6 1 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ46517.1 - 1.6 8.7 7.0 2 8.3 7.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ46519.1 - 0.0012 17.9 0.4 0.0012 17.9 0.4 6.3 5 2 0 5 5 5 2 Protein of unknown function (DUF2722) UCH PF00443.29 CDJ46520.1 - 5.1e-05 22.9 4.1 5.1e-05 22.9 4.1 2.5 2 1 0 2 2 1 1 Ubiquitin carboxyl-terminal hydrolase Activator_LAG-3 PF11498.8 CDJ46520.1 - 0.0043 16.1 14.9 0.0043 16.1 14.9 2.5 2 0 0 2 2 2 1 Transcriptional activator LAG-3 DUF2722 PF10846.8 CDJ46520.1 - 0.0051 15.8 13.4 0.0051 15.8 13.4 3.3 2 1 1 3 3 2 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ46520.1 - 0.0098 15.9 25.6 0.028 14.4 3.2 2.3 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) Lin-8 PF03353.15 CDJ46520.1 - 0.27 10.8 31.1 0.24 10.9 12.4 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist MMR1 PF08505.10 CDJ46520.1 - 0.43 10.8 29.3 2.4 8.4 11.7 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Macoilin PF09726.9 CDJ46520.1 - 1.1 7.8 24.4 0.14 10.7 8.0 2.3 2 0 0 2 2 2 0 Macoilin family TFIIA PF03153.13 CDJ46520.1 - 1.2 9.0 65.2 0.073 13.1 24.3 2.7 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4179 PF13786.6 CDJ46520.1 - 1.4 9.5 9.6 6.5 7.3 1.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4179) DUF2268 PF10026.9 CDJ46520.1 - 1.5 8.4 5.4 0.15 11.6 0.6 1.7 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) Sin_N PF04801.13 CDJ46520.1 - 2.1 7.4 26.2 0.56 9.4 8.1 2.2 2 0 0 2 2 2 0 Sin-like protein conserved region SLC12 PF03522.15 CDJ46520.1 - 6.2 5.7 16.9 4.1 6.3 3.8 2.1 2 0 0 2 2 2 0 Solute carrier family 12 cwf18 PF08315.12 CDJ46520.1 - 8 7.1 22.2 0.45 11.2 7.7 2.7 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor Zip PF02535.22 CDJ46521.1 - 0.0039 16.5 17.4 0.0088 15.3 17.4 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter SLC12 PF03522.15 CDJ46521.1 - 0.031 13.3 31.6 0.055 12.5 31.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 NAD_binding_6 PF08030.12 CDJ46521.1 - 0.22 11.7 0.0 0.22 11.7 0.0 3.2 1 1 1 2 2 2 0 Ferric reductase NAD binding domain DUF5470 PF17564.2 CDJ46521.1 - 0.22 11.7 3.5 0.83 9.9 3.5 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5470) Claudin_2 PF13903.6 CDJ46521.1 - 0.53 10.0 0.0 0.53 10.0 0.0 3.4 2 1 2 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction Presenilin PF01080.17 CDJ46521.1 - 1.5 7.5 46.1 0.023 13.5 37.9 1.9 2 1 0 2 2 2 0 Presenilin LMBR1 PF04791.16 CDJ46521.1 - 3 6.6 9.1 3.8 6.3 9.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SDA1 PF05285.12 CDJ46521.1 - 6.4 6.1 41.7 0.36 10.2 36.1 1.6 2 0 0 2 2 2 0 SDA1 Hid1 PF12722.7 CDJ46521.1 - 7.8 4.5 38.0 0.26 9.3 31.9 1.5 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein TFIIA PF03153.13 CDJ46522.1 - 0.0021 18.1 25.3 0.0021 18.1 25.3 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CD20 PF04103.15 CDJ46522.1 - 0.045 13.8 0.2 0.058 13.5 0.2 1.1 1 0 0 1 1 1 0 CD20-like family Spt20 PF12090.8 CDJ46522.1 - 0.086 12.4 27.3 0.1 12.2 27.3 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ46522.1 - 0.21 11.6 12.4 0.21 11.6 12.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FSA_C PF10479.9 CDJ46522.1 - 0.44 8.6 7.0 0.48 8.5 7.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus BAF1_ABF1 PF04684.13 CDJ46522.1 - 0.53 9.3 11.5 0.52 9.3 11.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Dehydrin PF00257.19 CDJ46522.1 - 0.55 10.8 11.5 0.78 10.3 11.5 1.4 1 0 0 1 1 1 0 Dehydrin DcuA_DcuB PF03605.14 CDJ46522.1 - 0.67 8.8 7.8 0.86 8.4 7.8 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter O-antigen_lig PF13425.6 CDJ46522.1 - 0.69 8.6 1.4 0.74 8.5 1.4 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SMYLE_N PF18615.1 CDJ46522.1 - 0.86 9.1 11.0 1 8.9 11.0 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain RAB3GAP2_N PF14655.6 CDJ46522.1 - 0.87 8.8 11.0 1 8.5 11.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DDHD PF02862.17 CDJ46522.1 - 1 9.5 9.0 1 9.5 9.0 1.1 1 0 0 1 1 1 0 DDHD domain FAM199X PF15814.5 CDJ46522.1 - 1 8.3 13.7 1.3 8.0 13.7 1.1 1 0 0 1 1 1 0 Protein family FAM199X Neur_chan_memb PF02932.16 CDJ46522.1 - 1.3 9.1 4.3 1.2 9.1 4.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 CDJ46522.1 - 1.3 9.0 7.1 1.4 8.9 7.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Serinc PF03348.15 CDJ46522.1 - 1.9 7.3 7.3 2.1 7.2 7.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2232 PF09991.9 CDJ46522.1 - 2.1 7.5 8.6 2.4 7.2 8.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) FHIPEP PF00771.20 CDJ46522.1 - 2.4 6.5 10.6 2.8 6.3 10.6 1.0 1 0 0 1 1 1 0 FHIPEP family Pex14_N PF04695.13 CDJ46522.1 - 2.7 8.6 24.2 3.4 8.3 24.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Coilin_N PF15862.5 CDJ46522.1 - 2.7 7.8 11.5 3.6 7.4 11.5 1.2 1 0 0 1 1 1 0 Coilin N-terminus GREB1 PF15782.5 CDJ46522.1 - 3.3 4.7 11.6 3.1 4.8 11.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-RING_2 PF13639.6 CDJ46523.1 - 1.6e-10 41.2 9.5 1.6e-10 41.2 9.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ46523.1 - 4.2e-08 32.9 8.0 4.2e-08 32.9 8.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ46523.1 - 1.3e-07 31.2 2.4 1.3e-07 31.2 2.4 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CDJ46523.1 - 3.3e-07 30.2 3.0 3.3e-07 30.2 3.0 3.1 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ46523.1 - 8.8e-06 25.5 8.8 8.8e-06 25.5 8.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ46523.1 - 1.1e-05 25.6 9.8 1.1e-05 25.6 9.8 3.2 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDJ46523.1 - 0.00035 20.5 8.5 0.00035 20.5 8.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDJ46523.1 - 0.0082 16.0 6.8 0.0082 16.0 6.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 CDJ46523.1 - 2.5 8.3 9.0 8.1 6.7 9.0 1.9 1 0 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 CDJ46523.1 - 3.4 7.8 13.5 0.15 12.1 4.9 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger RIFIN PF02009.16 CDJ46523.1 - 3.5 7.4 15.2 2 8.2 10.6 2.1 2 0 0 2 2 2 0 Rifin Peptidase_C13 PF01650.18 CDJ46524.1 - 8.7e-16 58.2 0.1 8.7e-16 58.2 0.1 1.6 2 0 0 2 2 1 1 Peptidase C13 family Nha1_C PF08619.10 CDJ46524.1 - 0.007 15.6 15.3 0.007 15.6 15.3 2.1 2 0 0 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus Presenilin PF01080.17 CDJ46524.1 - 0.0076 15.1 34.7 0.046 12.5 20.6 2.1 2 0 0 2 2 2 2 Presenilin Zip PF02535.22 CDJ46524.1 - 0.0087 15.3 16.0 0.015 14.5 7.8 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter MMR1 PF08505.10 CDJ46524.1 - 0.016 15.5 14.9 0.016 15.5 14.9 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein MDM10 PF12519.8 CDJ46524.1 - 0.028 13.3 21.6 0.043 12.7 2.3 2.2 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 DUF5327 PF17261.2 CDJ46524.1 - 0.029 15.1 12.3 0.029 15.1 12.3 3.5 3 1 1 4 4 2 0 Family of unknown function (DUF5327) DUF1644 PF07800.12 CDJ46524.1 - 0.088 12.9 0.4 0.088 12.9 0.4 3.1 2 1 1 3 3 2 0 Protein of unknown function (DUF1644) Suf PF05843.14 CDJ46524.1 - 0.12 12.4 34.8 0.2 11.6 8.4 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF5427 PF10310.9 CDJ46524.1 - 0.16 10.9 34.8 0.44 9.5 4.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5427) DUF913 PF06025.12 CDJ46524.1 - 0.4 9.6 17.4 0.99 8.3 8.7 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CAC1F_C PF16885.5 CDJ46524.1 - 0.51 9.9 20.5 0.73 9.4 9.8 2.1 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term NPR3 PF03666.13 CDJ46524.1 - 0.85 8.3 32.9 0.13 11.1 18.5 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4050 PF13259.6 CDJ46524.1 - 2.1 8.7 24.0 0.97 9.7 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Lin-8 PF03353.15 CDJ46524.1 - 2.3 7.7 31.7 2.5 7.6 15.8 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Pox_Ag35 PF03286.14 CDJ46524.1 - 2.9 7.6 25.8 0.97 9.2 0.7 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Neur_chan_memb PF02932.16 CDJ46524.1 - 4.3 7.3 24.9 1.2 9.1 2.6 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SURF2 PF05477.11 CDJ46524.1 - 4.9 6.8 31.2 3.3 7.4 19.2 2.2 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) DUF2052 PF09747.9 CDJ46524.1 - 5.1 7.2 42.3 0.22 11.6 4.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Isy1 PF06246.12 CDJ46524.1 - 7.7 6.0 32.6 0.84 9.1 3.0 2.2 2 0 0 2 2 2 0 Isy1-like splicing family Raftlin PF15250.6 CDJ46524.1 - 8.6 5.0 26.6 2.4 6.8 14.7 2.1 2 0 0 2 2 2 0 Raftlin VID27 PF08553.10 CDJ46525.1 - 0.0033 16.5 0.0 0.0033 16.5 0.0 1.0 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Caps_synth_GfcC PF06251.11 CDJ46525.1 - 0.15 11.7 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 Capsule biosynthesis GfcC SOBP PF15279.6 CDJ46526.1 - 1.5 9.3 33.0 2.5 8.6 33.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Pkinase PF00069.25 CDJ46527.1 - 3.2e-44 151.3 0.0 3.2e-44 151.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ46527.1 - 1.5e-21 76.9 6.3 9.7e-14 51.3 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Choline_kinase PF01633.20 CDJ46527.1 - 0.0024 17.5 0.0 0.0024 17.5 0.0 2.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CDJ46527.1 - 0.016 15.2 0.0 0.016 15.2 0.0 3.3 3 1 1 4 4 4 0 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ46527.1 - 0.28 10.8 0.0 0.28 10.8 0.0 3.4 3 1 1 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 FapA PF03961.13 CDJ46527.1 - 1.6 7.2 8.1 2.2 6.8 8.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4179 PF13786.6 CDJ46527.1 - 4.5 7.8 8.3 24 5.5 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) DUF4471 PF14740.6 CDJ46527.1 - 7.9 5.6 14.2 0.067 12.4 5.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Activator_LAG-3 PF11498.8 CDJ46528.1 - 0.0018 17.3 17.8 0.0018 17.3 17.8 6.7 4 1 3 7 7 7 1 Transcriptional activator LAG-3 Cyt_bd_oxida_II PF02322.15 CDJ46528.1 - 0.059 12.7 1.7 0.1 12.0 1.7 1.3 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II CD20 PF04103.15 CDJ46530.1 - 0.88 9.6 8.4 4.9 7.2 0.0 2.7 3 0 0 3 3 3 0 CD20-like family 7tm_7 PF08395.12 CDJ46530.1 - 1.4 8.0 8.1 2.4 7.3 8.1 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor Vir_act_alpha_C PF10400.9 CDJ46530.1 - 3.1 8.6 6.1 2.3 9.0 0.3 2.8 3 0 0 3 3 3 0 Virulence activator alpha C-term SR-25 PF10500.9 CDJ46530.1 - 5.6 6.5 13.8 1.4 8.5 10.6 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein His_Phos_1 PF00300.22 CDJ46531.1 - 2.4e-10 40.4 5.4 5.9e-07 29.4 0.5 2.3 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SUIM_assoc PF16619.5 CDJ46531.1 - 0.14 12.2 0.5 0.14 12.2 0.5 4.9 4 2 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 ALG3 PF05208.13 CDJ46531.1 - 0.23 10.9 0.2 0.3 10.4 0.2 1.2 1 0 0 1 1 1 0 ALG3 protein GREB1 PF15782.5 CDJ46533.1 - 0.068 10.3 40.7 0.084 10.0 40.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RBFA PF02033.18 CDJ46534.1 - 0.00021 21.7 0.1 0.00079 19.8 0.1 2.0 1 1 0 1 1 1 1 Ribosome-binding factor A SPX PF03105.19 CDJ46534.1 - 0.00088 19.3 15.2 0.00088 19.3 15.2 2.0 2 0 0 2 2 2 1 SPX domain Dehydrin PF00257.19 CDJ46534.1 - 0.0054 17.3 4.8 0.0054 17.3 4.8 5.9 3 1 2 5 5 5 1 Dehydrin HOOK PF05622.12 CDJ46535.1 - 4.3e-13 48.3 89.9 2.8e-11 42.3 89.9 2.6 1 1 0 1 1 1 1 HOOK protein DivIC PF04977.15 CDJ46535.1 - 0.003 17.3 13.9 0.003 17.3 13.9 8.5 4 2 2 7 7 7 2 Septum formation initiator WD40_alt PF14077.6 CDJ46535.1 - 0.31 11.0 12.4 1.2 9.0 0.0 3.8 3 1 0 3 3 3 0 Alternative WD40 repeat motif Caldesmon PF02029.15 CDJ46536.1 - 0.0096 14.7 47.0 0.017 13.9 47.0 1.4 1 0 0 1 1 1 1 Caldesmon TFIIF_alpha PF05793.12 CDJ46536.1 - 0.018 13.6 28.2 0.034 12.7 28.2 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SMYLE_N PF18615.1 CDJ46537.1 - 0.023 14.3 27.3 0.027 14.1 27.3 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SWI-SNF_Ssr4 PF08549.10 CDJ46539.1 - 0.077 11.6 2.2 0.16 10.5 2.2 1.5 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) AP2 PF00847.20 CDJ46541.1 - 7.4e-05 22.9 2.5 7.4e-05 22.9 2.5 2.1 2 0 0 2 2 2 1 AP2 domain TFIIA PF03153.13 CDJ46541.1 - 0.39 10.6 31.0 0.73 9.8 31.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCCH PF00642.24 CDJ46542.1 - 0.00012 21.9 15.2 0.00016 21.5 2.8 3.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ46542.1 - 0.0005 19.8 7.3 0.0036 17.1 2.8 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDJ46542.1 - 0.0016 18.4 15.4 0.004 17.2 1.6 4.2 4 1 0 4 4 4 2 Zinc finger domain Torus PF16131.5 CDJ46542.1 - 0.0028 18.3 0.0 0.0028 18.3 0.0 5.3 5 2 1 6 6 6 1 Torus domain zf-CCCH_2 PF14608.6 CDJ46542.1 - 0.2 12.2 6.7 6.5 7.4 0.5 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Hist_deacetyl PF00850.19 CDJ46543.1 - 7.2e-45 153.8 0.1 2.9e-32 112.4 0.1 3.5 4 0 0 4 4 3 2 Histone deacetylase domain Ank_5 PF13857.6 CDJ46543.1 - 1.7e-07 31.4 2.8 1e-06 28.9 0.2 3.1 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ46543.1 - 2.5e-07 31.2 0.0 0.00015 22.3 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ46543.1 - 1.3e-05 25.2 1.6 0.11 13.1 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CDJ46543.1 - 8e-05 22.9 8.4 0.0022 18.4 0.8 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CDJ46543.1 - 0.00012 22.6 1.9 0.009 16.6 0.2 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DUF572 PF04502.13 CDJ46543.1 - 0.00041 20.1 6.3 0.00041 20.1 6.3 3.2 4 0 0 4 4 3 1 Family of unknown function (DUF572) AF-4 PF05110.13 CDJ46543.1 - 0.00079 17.7 32.4 0.00079 17.7 32.4 6.1 6 1 0 6 6 3 1 AF-4 proto-oncoprotein TFIIA PF03153.13 CDJ46543.1 - 0.0013 18.8 22.9 0.0013 18.8 22.9 6.7 4 2 1 7 7 4 1 Transcription factor IIA, alpha/beta subunit Otopetrin PF03189.13 CDJ46543.1 - 0.19 10.5 0.8 0.32 9.8 0.4 1.6 2 0 0 2 2 2 0 Otopetrin EOS1 PF12326.8 CDJ46543.1 - 0.21 11.5 4.0 2.7 7.9 3.4 2.7 2 0 0 2 2 2 0 N-glycosylation protein Isy1 PF06246.12 CDJ46543.1 - 0.45 10.0 12.3 18 4.8 10.1 2.5 2 0 0 2 2 2 0 Isy1-like splicing family SLC12 PF03522.15 CDJ46543.1 - 0.56 9.2 10.2 0.06 12.4 4.9 1.9 2 0 0 2 2 2 0 Solute carrier family 12 Pkinase_fungal PF17667.1 CDJ46543.1 - 0.67 8.7 3.8 0.57 8.9 0.9 2.5 3 0 0 3 3 3 0 Fungal protein kinase FAM176 PF14851.6 CDJ46543.1 - 1.3 8.7 7.3 0.36 10.5 3.0 2.2 2 0 0 2 2 2 0 FAM176 family SpoIIP PF07454.11 CDJ46543.1 - 2.1 7.7 16.6 0.18 11.3 9.6 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CLN3 PF02487.17 CDJ46543.1 - 2.1 7.3 7.6 0.56 9.2 3.5 2.0 2 0 0 2 2 2 0 CLN3 protein eIF-3_zeta PF05091.12 CDJ46543.1 - 2.1 7.2 19.6 0.096 11.6 12.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) G0-G1_switch_2 PF15103.6 CDJ46543.1 - 3.1 8.3 14.5 1.8 9.0 9.2 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 bHLH-MYC_N PF14215.6 CDJ46543.1 - 4.2 7.6 10.9 0.9 9.8 4.3 2.8 3 0 0 3 3 2 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal CDC45 PF02724.14 CDJ46543.1 - 4.3 5.5 10.7 3.2 5.9 7.9 2.0 2 0 0 2 2 2 0 CDC45-like protein XRN_N PF03159.18 CDJ46543.1 - 6.4 6.1 10.9 14 5.0 10.9 1.5 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus SID-1_RNA_chan PF13965.6 CDJ46543.1 - 7.2 4.9 4.9 13 4.1 4.9 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ46543.1 - 8.8 5.1 7.1 23 3.8 7.1 1.6 1 0 0 1 1 1 0 Serine incorporator (Serinc) MCU PF04678.13 CDJ46543.1 - 9.9 6.2 7.6 19 5.3 5.4 2.5 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Presenilin PF01080.17 CDJ46543.1 - 9.9 4.8 27.3 0.0031 16.3 8.5 3.0 3 1 0 3 3 2 0 Presenilin DDRGK PF09756.9 CDJ46544.1 - 2.8e-42 144.5 14.8 2.8e-42 144.5 14.8 2.4 3 0 0 3 3 3 1 DDRGK domain TFIIA PF03153.13 CDJ46544.1 - 0.016 15.2 9.5 0.017 15.2 9.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Collagen PF01391.18 CDJ46544.1 - 0.074 12.8 16.0 0.14 11.9 16.0 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) RPA_C PF08784.11 CDJ46544.1 - 0.26 12.0 3.6 1.8 9.3 0.0 2.7 1 1 0 2 2 2 0 Replication protein A C terminal NAM-associated PF14303.6 CDJ46544.1 - 3.3 8.4 27.0 5.6 7.7 0.4 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain VIR_N PF15912.5 CDJ46544.1 - 3.7 7.1 8.1 5.9 6.4 8.1 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal MecA PF05389.12 CDJ46545.1 - 0.031 13.9 0.2 0.031 13.9 0.2 2.9 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) Hydrolase_4 PF12146.8 CDJ46545.1 - 0.59 9.3 14.1 0.1 11.8 5.5 3.2 1 1 3 4 4 4 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ46545.1 - 0.89 9.1 6.7 0.22 11.1 0.1 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold EOS1 PF12326.8 CDJ46545.1 - 1.5 8.7 4.6 9.5 6.1 0.1 2.9 3 0 0 3 3 3 0 N-glycosylation protein Methyltransf_34 PF11312.8 CDJ46545.1 - 7.7 5.7 18.4 2.3 7.4 11.1 2.6 1 1 1 2 2 2 0 Putative SAM-dependent methyltransferase Presenilin PF01080.17 CDJ46546.1 - 0.0043 15.9 30.3 0.0051 15.6 30.3 1.1 1 0 0 1 1 1 1 Presenilin SARAF PF06682.12 CDJ46546.1 - 0.0054 16.4 16.4 0.0066 16.1 16.4 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis SAGA-Tad1 PF12767.7 CDJ46546.1 - 0.07 12.9 18.8 0.085 12.6 18.8 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RR_TM4-6 PF06459.12 CDJ46546.1 - 0.074 12.9 22.4 0.092 12.6 22.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5523 PF17661.1 CDJ46546.1 - 0.21 11.3 25.5 0.26 10.9 25.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF2828 PF11443.8 CDJ46546.1 - 0.31 9.1 21.2 0.43 8.6 21.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RIFIN PF02009.16 CDJ46546.1 - 0.77 9.6 20.3 0.98 9.3 20.3 1.1 1 0 0 1 1 1 0 Rifin PA26 PF04636.13 CDJ46546.1 - 0.88 8.4 16.6 1 8.2 16.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Rtf2 PF04641.12 CDJ46546.1 - 1.4 8.3 19.9 2 7.7 19.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger AUX_IAA PF02309.16 CDJ46546.1 - 1.5 8.6 15.3 1.7 8.5 15.3 1.2 1 0 0 1 1 1 0 AUX/IAA family FAM60A PF15396.6 CDJ46546.1 - 1.6 8.7 20.3 2.2 8.2 20.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Pol_alpha_B_N PF08418.10 CDJ46546.1 - 1.7 8.6 23.2 2.2 8.2 23.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal ALMT PF11744.8 CDJ46546.1 - 1.7 7.4 19.4 2.3 7.0 19.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter LAP1C PF05609.12 CDJ46546.1 - 2.1 7.4 23.6 2.3 7.2 23.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 CDJ46546.1 - 2.4 6.4 23.5 3.3 5.9 23.5 1.2 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ46546.1 - 2.6 6.9 27.7 3.2 6.7 27.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 XRN_M PF17846.1 CDJ46546.1 - 3 6.7 19.3 3.6 6.4 19.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain SPG4 PF17325.2 CDJ46546.1 - 3.4 8.8 20.3 0.51 11.4 5.2 2.2 2 0 0 2 2 2 0 Stationary phase protein 4 PAT1 PF09770.9 CDJ46546.1 - 3.6 5.7 43.6 4 5.6 43.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CobT PF06213.12 CDJ46546.1 - 6.7 6.0 37.0 0.76 9.1 12.2 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT XAP5 PF04921.14 CDJ46546.1 - 7.7 6.3 22.2 10 5.8 22.2 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator PGA_cap PF09587.10 CDJ46546.1 - 8.1 5.8 14.6 6.2 6.2 13.4 1.4 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap EB1 PF03271.17 CDJ46547.1 - 1.7e-12 47.3 0.1 3.2e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CDJ46547.1 - 0.00012 22.3 0.1 0.00017 21.7 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain AAA PF00004.29 CDJ46548.1 - 2.4e-11 44.2 1.3 5.6e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ46548.1 - 0.00011 21.9 0.2 0.37 10.6 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain SR-25 PF10500.9 CDJ46548.1 - 0.00018 21.2 5.1 0.00018 21.2 5.1 10.3 7 3 3 10 10 10 5 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 CDJ46548.1 - 0.002 18.7 15.9 0.027 15.0 1.9 2.5 2 0 0 2 2 2 2 AAA domain TFIIA PF03153.13 CDJ46548.1 - 0.0027 17.8 16.5 0.0027 17.8 16.5 5.6 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit HTH_23 PF13384.6 CDJ46548.1 - 0.028 14.2 0.4 0.1 12.5 0.4 2.0 1 0 0 1 1 1 0 Homeodomain-like domain Spore_YhcN_YlaJ PF09580.10 CDJ46548.1 - 0.048 13.7 6.6 0.36 10.9 0.2 2.4 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) SR-25 PF10500.9 CDJ46549.1 - 0.0015 18.2 17.7 0.0015 18.2 17.7 6.3 2 2 3 5 5 5 2 Nuclear RNA-splicing-associated protein F-box-like PF12937.7 CDJ46549.1 - 0.0099 15.8 1.2 0.0099 15.8 1.2 2.2 2 0 0 2 2 2 1 F-box-like SelP_N PF04592.14 CDJ46550.1 - 0.12 11.7 30.3 0.13 11.6 30.3 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region V_ATPase_I PF01496.19 CDJ46550.1 - 0.22 9.4 25.5 0.22 9.4 25.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pex14_N PF04695.13 CDJ46550.1 - 0.26 12.0 36.5 0.28 11.8 36.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.13 CDJ46550.1 - 0.49 9.4 24.9 0.56 9.2 24.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Connexin PF00029.19 CDJ46550.1 - 0.8 9.4 18.1 0.96 9.2 18.1 1.2 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ46550.1 - 0.9 8.2 30.8 0.95 8.2 30.8 1.0 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 CDJ46550.1 - 0.95 7.8 11.4 1 7.7 11.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 O-antigen_lig PF13425.6 CDJ46550.1 - 1.1 8.0 9.6 1.1 7.9 9.6 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Peptidase_U57 PF05582.12 CDJ46550.1 - 1.1 8.4 17.2 1.2 8.3 17.2 1.0 1 0 0 1 1 1 0 YabG peptidase U57 RR_TM4-6 PF06459.12 CDJ46550.1 - 1.5 8.6 25.1 1.6 8.5 25.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ureide_permease PF07168.11 CDJ46550.1 - 1.7 7.3 13.0 2 7.1 13.0 1.1 1 0 0 1 1 1 0 Ureide permease SpoIIP PF07454.11 CDJ46550.1 - 1.8 8.0 24.4 2.2 7.7 24.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 CDJ46550.1 - 1.9 7.2 22.3 2 7.1 22.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RPN2_C PF18004.1 CDJ46550.1 - 1.9 8.4 20.3 2.6 7.9 20.3 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain VIR_N PF15912.5 CDJ46550.1 - 2.2 7.8 14.0 2.2 7.8 14.0 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal DUF913 PF06025.12 CDJ46550.1 - 2.4 7.1 16.2 2.4 7.0 16.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Serinc PF03348.15 CDJ46550.1 - 2.7 6.8 15.0 3.2 6.6 15.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2126 PF09899.9 CDJ46550.1 - 3.2 5.7 17.0 3.4 5.6 17.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RP-C_C PF11800.8 CDJ46550.1 - 3.3 7.7 22.5 3.7 7.6 22.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region HemX PF04375.14 CDJ46550.1 - 3.4 6.8 45.2 3.9 6.7 45.2 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TRAP_alpha PF03896.16 CDJ46550.1 - 3.9 6.6 13.1 4.5 6.4 13.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CLN3 PF02487.17 CDJ46550.1 - 4 6.4 19.0 4 6.4 19.0 1.0 1 0 0 1 1 1 0 CLN3 protein DUF3984 PF13136.6 CDJ46550.1 - 4.2 6.7 22.4 4.9 6.5 22.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) PAT1 PF09770.9 CDJ46550.1 - 5.1 5.2 41.9 5.2 5.2 41.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3332 PF11810.8 CDJ46550.1 - 5.2 6.7 10.1 5.2 6.7 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Endostatin PF06482.11 CDJ46550.1 - 5.2 6.4 24.5 5.4 6.4 24.5 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PTPRCAP PF15713.5 CDJ46550.1 - 5.3 7.3 27.0 5.9 7.2 27.0 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF1980 PF09323.10 CDJ46550.1 - 5.5 6.9 16.5 7.5 6.4 16.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CSG2 PF16965.5 CDJ46550.1 - 5.6 5.8 14.2 6.4 5.6 14.2 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2561 PF10812.8 CDJ46550.1 - 5.8 6.9 8.3 6.8 6.7 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF4228 PF14009.6 CDJ46550.1 - 6 7.2 17.3 6.5 7.1 17.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Tim54 PF11711.8 CDJ46550.1 - 6.2 5.5 22.2 6.8 5.4 22.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S49_N PF08496.10 CDJ46550.1 - 6.5 6.8 21.3 9.1 6.3 21.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM60A PF15396.6 CDJ46550.1 - 7.6 6.5 20.4 8.4 6.3 20.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CCDC53 PF10152.9 CDJ46550.1 - 7.7 6.9 27.6 9.8 6.6 27.6 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4446 PF14584.6 CDJ46550.1 - 7.8 6.5 9.9 11 6.0 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2828 PF11443.8 CDJ46550.1 - 8.8 4.3 26.1 9.4 4.2 26.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Otopetrin PF03189.13 CDJ46554.1 - 0.15 10.8 4.6 0.13 11.0 0.8 2.2 2 0 0 2 2 2 0 Otopetrin PAT1 PF09770.9 CDJ46554.1 - 5.6 5.1 64.1 1.1 7.4 55.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ46554.1 - 5.8 5.6 41.9 1.2 7.8 1.4 2.8 3 0 0 3 3 3 0 Presenilin Pkinase_fungal PF17667.1 CDJ46554.1 - 9.5 4.9 11.5 0.45 9.2 4.2 2.2 2 0 0 2 2 2 0 Fungal protein kinase rve PF00665.26 CDJ46555.1 - 6e-13 49.0 0.1 2.8e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ46555.1 - 1.2e-12 47.7 1.5 3.4e-12 46.3 1.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CDJ46555.1 - 4.3e-07 29.7 0.0 8.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ46555.1 - 0.0025 18.0 0.1 0.0054 17.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 CDJ46555.1 - 0.0076 16.1 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RskA PF10099.9 CDJ46556.1 - 5.1 7.3 57.0 1.6e+02 2.5 21.9 4.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA WD40 PF00400.32 CDJ46557.1 - 0.0053 17.6 4.4 1.5 9.8 0.0 5.2 6 0 0 6 6 6 1 WD domain, G-beta repeat SUIM_assoc PF16619.5 CDJ46557.1 - 0.011 15.8 1.4 0.011 15.8 1.4 5.2 6 0 0 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 Nop16 PF09420.10 CDJ46557.1 - 0.074 13.1 3.8 0.36 10.8 0.0 3.1 3 0 0 3 3 3 0 Ribosome biogenesis protein Nop16 Orf78 PF06024.12 CDJ46557.1 - 3.9 7.8 5.0 32 4.9 0.1 3.6 3 0 0 3 3 3 0 Orf78 (ac78) RskA PF10099.9 CDJ46558.1 - 3e-08 34.2 15.1 8.1e-07 29.5 0.8 13.4 2 2 6 10 10 10 2 Anti-sigma-K factor rskA PIG-U PF06728.13 CDJ46559.1 - 5.4e-21 75.1 21.4 9.7e-19 67.7 16.8 4.4 1 1 1 2 2 2 2 GPI transamidase subunit PIG-U Otopetrin PF03189.13 CDJ46559.1 - 1.2e-07 31.0 50.6 0.081 11.7 0.0 6.6 3 2 1 4 4 4 2 Otopetrin SPX PF03105.19 CDJ46559.1 - 0.0014 18.6 35.3 0.0014 18.6 35.3 3.7 2 1 1 3 3 3 2 SPX domain MID_MedPIWI PF18296.1 CDJ46559.1 - 0.081 12.7 0.0 0.081 12.7 0.0 7.7 1 1 3 6 6 6 0 MID domain of medPIWI CD20 PF04103.15 CDJ46560.1 - 0.13 12.4 0.3 0.15 12.1 0.3 1.2 1 0 0 1 1 1 0 CD20-like family Miga PF10265.9 CDJ46560.1 - 0.21 10.5 14.0 0.21 10.5 14.0 1.0 1 0 0 1 1 1 0 Mitoguardin SID-1_RNA_chan PF13965.6 CDJ46560.1 - 0.55 8.6 9.4 0.56 8.6 9.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 O-antigen_lig PF13425.6 CDJ46560.1 - 0.67 8.7 9.3 0.72 8.6 9.3 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein BAF1_ABF1 PF04684.13 CDJ46560.1 - 1.1 8.2 23.9 1.2 8.1 23.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor R_equi_Vir PF05526.11 CDJ46560.1 - 2.7 7.8 14.4 3.2 7.6 14.4 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SelP_N PF04592.14 CDJ46560.1 - 4 6.8 20.0 4 6.8 20.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2232 PF09991.9 CDJ46560.1 - 6 6.0 5.7 7.4 5.7 5.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) NEMP PF10225.9 CDJ46560.1 - 6.1 6.4 10.7 6.4 6.4 10.7 1.1 1 0 0 1 1 1 0 NEMP family RPN2_C PF18004.1 CDJ46560.1 - 6.2 6.7 23.6 7.1 6.5 23.6 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RskA PF10099.9 CDJ46561.1 - 0.0026 18.1 3.0 0.0026 18.1 3.0 7.0 2 2 3 5 5 5 2 Anti-sigma-K factor rskA PIP5K PF01504.18 CDJ46562.1 - 6.2e-76 255.2 0.0 6.2e-76 255.2 0.0 4.0 3 1 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase Shadoo PF14999.6 CDJ46562.1 - 0.47 10.5 8.0 1.6 8.9 0.5 2.8 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.19 CDJ46562.1 - 7.7 7.2 28.5 3 8.5 4.5 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein HSP70 PF00012.20 CDJ46563.1 - 6.4e-19 67.6 9.6 4e-13 48.4 5.3 4.4 3 2 0 3 3 3 2 Hsp70 protein SR-25 PF10500.9 CDJ46563.1 - 0.0014 18.3 16.8 0.0014 18.3 16.8 4.0 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein AAA PF00004.29 CDJ46565.1 - 7.8e-36 123.4 0.0 1.9e-15 57.4 0.0 5.5 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) WD40 PF00400.32 CDJ46565.1 - 9.2e-29 99.1 20.1 6e-06 26.9 0.8 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat AAA_lid_3 PF17862.1 CDJ46565.1 - 1.5e-13 50.3 4.3 1.8e-08 34.1 0.1 2.9 2 0 0 2 2 2 2 AAA+ lid domain ANAPC4_WD40 PF12894.7 CDJ46565.1 - 1.9e-09 37.7 6.9 0.21 11.9 0.0 5.2 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain AAA_5 PF07728.14 CDJ46565.1 - 4.8e-08 33.1 0.0 0.0058 16.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CDJ46565.1 - 1.4e-07 31.4 0.0 0.03 14.1 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 CDJ46565.1 - 1.8e-07 31.5 0.0 0.027 14.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 CDJ46565.1 - 2.2e-07 31.5 3.4 0.0028 18.2 0.0 4.1 4 0 0 4 4 3 2 AAA domain Mg_chelatase PF01078.21 CDJ46565.1 - 5e-07 29.3 2.2 0.022 14.2 0.1 3.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CDJ46565.1 - 1.9e-06 27.7 0.0 0.015 15.0 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CDJ46565.1 - 4.4e-06 26.1 0.0 0.053 12.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_16 PF13191.6 CDJ46565.1 - 7.3e-05 23.2 1.1 7.3e-05 23.2 1.1 8.4 6 2 1 7 7 4 2 AAA ATPase domain AAA_22 PF13401.6 CDJ46565.1 - 0.00032 21.0 12.7 0.02 15.2 0.0 4.4 4 0 0 4 4 3 2 AAA domain AAA_7 PF12775.7 CDJ46565.1 - 0.00093 18.8 0.0 0.73 9.3 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 CDJ46565.1 - 0.001 19.1 0.1 0.51 10.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Hydin_ADK PF17213.3 CDJ46565.1 - 0.0011 19.2 3.8 0.0011 19.2 3.8 10.4 6 2 3 9 9 2 1 Hydin Adenylate kinase-like domain DUF2722 PF10846.8 CDJ46565.1 - 0.0016 17.5 0.4 0.0016 17.5 0.4 10.6 7 3 2 10 10 5 2 Protein of unknown function (DUF2722) AAA_33 PF13671.6 CDJ46565.1 - 0.0016 18.6 0.0 0.0016 18.6 0.0 6.9 7 0 0 7 7 4 2 AAA domain DUF755 PF05501.11 CDJ46565.1 - 0.002 18.4 19.4 0.002 18.4 19.4 14.9 10 5 2 12 12 3 1 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ46565.1 - 0.0038 16.9 17.1 0.0038 16.9 17.1 13.5 9 4 3 12 12 7 3 Nuclear RNA-splicing-associated protein NACHT PF05729.12 CDJ46565.1 - 0.0063 16.4 5.0 2.3 8.1 0.0 4.1 3 0 0 3 3 3 2 NACHT domain SUIM_assoc PF16619.5 CDJ46565.1 - 0.0072 16.4 1.5 0.0072 16.4 1.5 15.5 10 4 1 11 11 5 2 Unstructured region C-term to UIM in Ataxin3 Ge1_WD40 PF16529.5 CDJ46565.1 - 0.0092 15.0 0.1 0.85 8.5 0.2 3.1 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TsaE PF02367.17 CDJ46565.1 - 0.02 14.9 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 CDJ46565.1 - 0.032 14.1 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CDJ46565.1 - 0.27 10.9 7.7 2.2 8.0 0.0 3.8 4 0 0 4 4 2 0 AAA domain AAA_17 PF13207.6 CDJ46565.1 - 3.2 8.2 0.0 1.8 9.0 0.0 5.4 6 2 0 6 6 4 0 AAA domain DUF4148 PF13663.6 CDJ46566.1 - 0.23 11.7 0.2 0.23 11.7 0.2 5.1 4 2 0 4 4 4 0 Domain of unknown function (DUF4148) UL11 PF11094.8 CDJ46566.1 - 1.9 8.4 5.8 3.7 7.5 5.8 1.4 1 0 0 1 1 1 0 Membrane-associated tegument protein PHD PF00628.29 CDJ46567.1 - 8.8e-07 28.7 4.1 1.6e-05 24.7 2.7 2.8 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 CDJ46567.1 - 0.0026 17.4 1.6 0.0026 17.4 1.6 5.5 5 3 2 7 7 7 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 CDJ46567.1 - 0.0034 16.9 3.1 0.037 13.6 0.7 2.5 2 0 0 2 2 2 1 PHD-finger DUF1635 PF07795.11 CDJ46567.1 - 0.0053 16.7 15.7 0.0053 16.7 15.7 7.0 3 2 4 7 7 7 1 Protein of unknown function (DUF1635) DUF755 PF05501.11 CDJ46567.1 - 0.011 16.1 17.9 0.011 16.1 17.9 9.8 7 3 2 9 9 9 0 Domain of unknown function (DUF755) Prok-RING_1 PF14446.6 CDJ46567.1 - 0.22 11.5 3.7 0.54 10.2 3.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 SPX PF03105.19 CDJ46568.1 - 0.0028 17.6 21.5 0.0039 17.2 21.5 1.2 1 0 0 1 1 1 1 SPX domain Utp14 PF04615.13 CDJ46568.1 - 0.028 13.0 13.7 0.033 12.8 13.7 1.1 1 0 0 1 1 1 0 Utp14 protein Ndc1_Nup PF09531.10 CDJ46568.1 - 0.03 13.0 10.9 0.045 12.5 10.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 CDJ46568.1 - 0.034 12.7 17.4 0.048 12.2 17.4 1.3 1 0 0 1 1 1 0 Macoilin family SLC12 PF03522.15 CDJ46568.1 - 0.42 9.6 8.2 0.61 9.0 8.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 CDJ46568.1 - 0.52 9.1 5.0 0.6 8.9 5.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ46568.1 - 0.67 8.1 12.4 0.85 7.8 12.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HSD3 PF15244.6 CDJ46568.1 - 0.79 9.2 15.6 1.1 8.7 15.6 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Smg8_Smg9 PF10220.9 CDJ46568.1 - 0.89 7.8 12.1 1.1 7.4 12.1 1.2 1 0 0 1 1 1 0 Smg8_Smg9 PI3K_1B_p101 PF10486.9 CDJ46568.1 - 1.9 6.2 13.1 2.5 5.7 13.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIA PF03153.13 CDJ46568.1 - 3.7 7.4 26.8 5.1 7.0 26.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FXMRP1_C_core PF12235.8 CDJ46568.1 - 5.8 7.6 21.3 12 6.5 16.4 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal EF-hand_13 PF17958.1 CDJ46569.1 - 2e-11 43.6 0.0 4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CDJ46569.1 - 7.6e-07 29.5 0.8 0.22 12.0 0.6 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ46569.1 - 0.00053 19.7 0.1 0.18 11.8 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CDJ46569.1 - 0.012 15.1 0.0 0.056 13.0 0.0 2.0 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 CDJ46569.1 - 0.029 13.8 0.0 0.073 12.6 0.0 1.7 1 0 0 1 1 1 0 EF hand SURF2 PF05477.11 CDJ46570.1 - 0.27 10.9 21.9 0.35 10.5 21.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PAP1 PF08601.10 CDJ46570.1 - 1.3 8.7 21.6 2 8.0 21.6 1.4 1 1 0 1 1 1 0 Transcription factor PAP1 SAPS PF04499.15 CDJ46570.1 - 1.4 7.6 14.4 2 7.1 14.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIA PF03153.13 CDJ46570.1 - 1.5 8.8 22.8 1.8 8.4 22.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sin_N PF04801.13 CDJ46570.1 - 3.5 6.7 18.0 4.7 6.3 18.0 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF702 PF05142.12 CDJ46570.1 - 4.6 7.7 14.9 0.79 10.2 10.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Glycogen_syn PF05693.13 CDJ46570.1 - 5.8 5.3 6.7 7.1 5.0 6.7 1.1 1 0 0 1 1 1 0 Glycogen synthase Coilin_N PF15862.5 CDJ46571.1 - 0.5 10.2 7.2 0.58 10.0 7.2 1.3 1 0 0 1 1 1 0 Coilin N-terminus TFIIA PF03153.13 CDJ46571.1 - 1.5 8.7 19.2 1.6 8.7 19.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3682 PF12446.8 CDJ46572.1 - 0.024 15.1 16.6 0.03 14.8 16.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF4179 PF13786.6 CDJ46572.1 - 0.17 12.4 0.6 0.19 12.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) MRI PF15325.6 CDJ46572.1 - 0.21 12.7 1.7 0.21 12.7 1.7 1.0 1 0 0 1 1 1 0 Modulator of retrovirus infection RskA PF10099.9 CDJ46572.1 - 0.39 11.0 14.8 0.5 10.6 14.8 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3533 PF12051.8 CDJ46572.1 - 0.39 9.6 3.7 0.44 9.4 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) OmpH PF03938.14 CDJ46572.1 - 0.88 9.9 19.0 0.95 9.8 19.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Activator_LAG-3 PF11498.8 CDJ46572.1 - 2.1 7.2 24.3 1.9 7.4 24.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3450 PF11932.8 CDJ46572.1 - 2.1 7.6 17.2 2.4 7.4 17.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) R_equi_Vir PF05526.11 CDJ46572.1 - 2.1 8.2 6.7 2.4 8.0 6.7 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Suf PF05843.14 CDJ46572.1 - 4.9 7.0 9.9 5 7.0 9.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TrbI PF03743.14 CDJ46572.1 - 5.1 6.9 11.2 5.3 6.8 11.2 1.0 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein DUF3573 PF12097.8 CDJ46572.1 - 7.6 5.2 6.9 7.5 5.3 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Spt20 PF12090.8 CDJ46572.1 - 9.6 5.7 20.5 10 5.7 20.5 1.1 1 0 0 1 1 1 0 Spt20 family DEAD PF00270.29 CDJ46573.1 - 7.1e-17 61.7 0.2 2e-15 57.0 0.2 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.14 CDJ46573.1 - 0.033 13.0 0.0 0.033 13.0 0.0 2.0 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Herpes_UL36 PF03586.13 CDJ46573.1 - 0.99 8.7 4.9 1.8 7.9 4.9 1.3 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Presenilin PF01080.17 CDJ46573.1 - 2.7 6.7 10.9 3.1 6.5 5.9 2.1 2 0 0 2 2 2 0 Presenilin SPX PF03105.19 CDJ46573.1 - 7.5 6.4 20.2 2.9 7.7 15.5 2.3 2 1 0 2 2 2 0 SPX domain BRF1 PF07741.13 CDJ46573.1 - 7.9 6.9 8.8 29 5.1 0.4 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain ABC2_membrane_3 PF12698.7 CDJ46574.1 - 0.0088 15.2 0.7 0.01 15.0 0.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ODV-E18 PF10717.9 CDJ46574.1 - 0.032 14.1 1.0 0.052 13.4 1.0 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 GREB1 PF15782.5 CDJ46574.1 - 2.2 5.3 40.3 2.4 5.2 40.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_M56 PF05569.11 CDJ46574.1 - 4.9 6.3 9.8 10 5.2 9.7 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF3881 PF12997.7 CDJ46575.1 - 4 6.6 6.4 2.9 7.0 0.6 2.7 2 1 1 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3881) EIF4E-T PF10477.9 CDJ46576.1 - 2.8 6.6 21.5 3.6 6.3 21.5 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E TMEM171 PF15471.6 CDJ46577.1 - 0.029 13.3 0.1 0.029 13.3 0.1 2.9 3 0 0 3 3 3 0 Transmembrane protein family 171 CD20 PF04103.15 CDJ46577.1 - 0.03 14.4 3.2 0.4 10.8 1.0 2.7 2 0 0 2 2 2 0 CD20-like family Fasciclin PF02469.22 CDJ46577.1 - 0.033 14.4 1.0 0.12 12.6 0.1 2.4 2 0 0 2 2 2 0 Fasciclin domain DUF2151 PF10221.9 CDJ46577.1 - 0.16 10.6 12.6 0.33 9.5 12.6 1.5 1 0 0 1 1 1 0 Cell cycle and development regulator LMBR1 PF04791.16 CDJ46577.1 - 2.7 6.8 22.5 0.012 14.6 11.8 2.1 1 1 1 2 2 2 0 LMBR1-like membrane protein Utp14 PF04615.13 CDJ46578.1 - 5.7e-05 21.9 10.6 7.3e-05 21.6 10.6 1.1 1 0 0 1 1 1 1 Utp14 protein Sporozoite_P67 PF05642.11 CDJ46578.1 - 0.00041 18.6 18.0 0.00077 17.7 18.0 1.4 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CD99L2 PF12301.8 CDJ46578.1 - 0.0094 16.3 3.0 0.0094 16.3 3.0 1.7 2 0 0 2 2 2 1 CD99 antigen like protein 2 MID_MedPIWI PF18296.1 CDJ46578.1 - 1.5 8.6 21.1 0.4 10.4 0.3 2.3 2 0 0 2 2 2 0 MID domain of medPIWI FUSC PF04632.12 CDJ46578.1 - 6.2 5.2 17.3 11 4.4 17.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family PPP4R2 PF09184.11 CDJ46578.1 - 9.3 5.7 13.0 0.95 9.0 6.2 2.1 2 0 0 2 2 2 0 PPP4R2 CCSAP PF15748.5 CDJ46579.1 - 0.027 14.6 29.7 0.031 14.5 29.7 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FAM199X PF15814.5 CDJ46579.1 - 0.55 9.2 26.2 0.77 8.7 26.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X RSRP PF17069.5 CDJ46579.1 - 0.57 9.7 31.4 0.75 9.3 31.4 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Velvet PF11754.8 CDJ46579.1 - 0.99 9.3 25.9 1.2 9.0 25.9 1.1 1 0 0 1 1 1 0 Velvet factor Activator_LAG-3 PF11498.8 CDJ46579.1 - 1.1 8.1 46.9 1.2 8.0 46.9 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PPP4R2 PF09184.11 CDJ46579.1 - 2.1 7.8 21.2 2.4 7.7 21.2 1.0 1 0 0 1 1 1 0 PPP4R2 NAM-associated PF14303.6 CDJ46579.1 - 3.2 8.5 29.6 4 8.1 29.6 1.0 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PPL5 PF18168.1 CDJ46579.1 - 4.4 6.5 15.3 6.8 5.9 15.3 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DUF1682 PF07946.14 CDJ46579.1 - 4.7 6.3 18.4 5.2 6.2 18.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) eIF-3_zeta PF05091.12 CDJ46579.1 - 5.7 5.8 25.5 5.9 5.8 25.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PI3K_1B_p101 PF10486.9 CDJ46579.1 - 5.8 4.6 21.7 7.1 4.3 21.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PA26 PF04636.13 CDJ46579.1 - 6.9 5.5 20.8 7.5 5.3 20.8 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) AAA_23 PF13476.6 CDJ46579.1 - 8.8 6.8 22.6 11 6.5 22.6 1.1 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 CDJ46579.1 - 8.8 6.1 26.2 9.9 5.9 26.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SUIM_assoc PF16619.5 CDJ46580.1 - 0.0047 17.0 6.3 0.0047 17.0 6.3 4.3 3 1 1 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 PEX11 PF05648.14 CDJ46580.1 - 0.016 14.7 5.8 0.16 11.4 1.6 2.2 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DUF4179 PF13786.6 CDJ46580.1 - 0.22 12.0 0.2 0.22 12.0 0.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) Sin_N PF04801.13 CDJ46580.1 - 0.73 9.0 21.3 2.1 7.5 12.2 2.2 2 0 0 2 2 2 0 Sin-like protein conserved region NUC194 PF08163.12 CDJ46580.1 - 0.74 8.7 8.6 0.074 12.0 2.4 1.9 2 0 0 2 2 2 0 NUC194 domain MMR1 PF08505.10 CDJ46580.1 - 5.4 7.2 16.8 8.5 6.6 8.7 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF4228 PF14009.6 CDJ46580.1 - 5.4 7.4 13.9 9.5 6.6 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Connexin PF00029.19 CDJ46580.1 - 5.6 6.7 6.8 4.6 6.9 2.8 2.1 2 0 0 2 2 2 0 Connexin HemX PF04375.14 CDJ46580.1 - 9.2 5.4 42.5 4 6.6 28.6 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase CSG2 PF16965.5 CDJ46581.1 - 0.64 8.9 13.2 0.97 8.3 13.2 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator SARAF PF06682.12 CDJ46581.1 - 3.8 7.1 21.1 6.2 6.4 21.1 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Peroxin-13_N PF04088.13 CDJ46581.1 - 3.9 7.7 18.3 2 8.7 1.4 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region SLC12 PF03522.15 CDJ46581.1 - 4 6.4 29.1 5.2 6.0 29.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF719 PF05334.13 CDJ46581.1 - 5.3 7.2 23.8 1 9.5 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Connexin PF00029.19 CDJ46581.1 - 8 6.1 22.2 1.3 8.7 0.9 2.2 2 0 0 2 2 2 0 Connexin Sin_N PF04801.13 CDJ46582.1 - 0.025 13.8 0.0 0.025 13.8 0.0 3.3 1 1 2 3 3 3 0 Sin-like protein conserved region Caldesmon PF02029.15 CDJ46582.1 - 0.14 10.9 85.2 0.02 13.7 77.2 2.4 2 0 0 2 2 2 0 Caldesmon RskA PF10099.9 CDJ46583.1 - 0.003 17.9 15.0 0.0049 17.2 15.0 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ46583.1 - 0.0058 17.2 3.7 0.0095 16.5 3.7 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2721 PF11026.8 CDJ46583.1 - 0.095 12.6 0.0 0.095 12.6 0.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2721) SecA_DEAD PF07517.14 CDJ46583.1 - 0.11 11.8 2.3 0.16 11.3 2.3 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain TFIIA PF03153.13 CDJ46583.1 - 0.43 10.5 31.9 0.57 10.1 31.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3138 PF11336.8 CDJ46583.1 - 0.45 9.1 13.9 0.63 8.6 13.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FAM70 PF14967.6 CDJ46583.1 - 1.2 8.6 3.3 1.2 8.6 3.3 1.3 1 0 0 1 1 1 0 FAM70 protein Med15 PF09606.10 CDJ46583.1 - 1.5 7.4 29.5 1.9 7.0 29.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RNase_3_N PF18497.1 CDJ46583.1 - 1.8 8.8 11.5 6.7 7.0 3.1 2.8 2 1 1 3 3 3 0 Ribonuclease III N-terminal domain ETRAMP PF09716.10 CDJ46583.1 - 2.3 8.3 5.6 7.7 6.7 5.6 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) FapA PF03961.13 CDJ46583.1 - 2.9 6.4 6.7 4.2 5.8 6.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A MCU PF04678.13 CDJ46583.1 - 3.2 7.8 11.8 0.25 11.4 5.7 2.0 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF4834 PF16118.5 CDJ46583.1 - 4.1 8.4 6.5 4.4 8.3 2.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) CCDC53 PF10152.9 CDJ46583.1 - 6.9 7.1 14.8 15 6.0 14.8 1.7 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex ALMT PF11744.8 CDJ46583.1 - 7.1 5.3 8.1 8.5 5.1 8.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Apt1 PF10351.9 CDJ46584.1 - 0.34 9.7 2.6 0.36 9.6 2.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOBP PF15279.6 CDJ46584.1 - 3.4 8.2 22.4 4.6 7.8 22.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2722 PF10846.8 CDJ46585.1 - 0.0016 17.4 7.1 0.0016 17.4 7.1 3.5 2 1 1 3 3 2 1 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 CDJ46585.1 - 0.0085 15.1 16.3 0.064 12.2 1.9 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RskA PF10099.9 CDJ46585.1 - 0.01 16.1 23.4 0.01 16.1 23.4 8.4 1 1 2 4 4 2 0 Anti-sigma-K factor rskA CIAPIN1 PF05093.13 CDJ46585.1 - 0.016 15.7 0.2 0.016 15.7 0.2 3.6 2 1 0 2 2 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis MAT1 PF06391.13 CDJ46585.1 - 0.095 12.5 28.0 0.089 12.6 11.2 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 PIP5K PF01504.18 CDJ46585.1 - 0.28 10.4 7.9 1.4 8.1 0.2 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF3678 PF12435.8 CDJ46585.1 - 0.31 10.5 8.5 0.87 9.0 0.5 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) DUF4471 PF14740.6 CDJ46585.1 - 0.35 10.0 6.1 0.66 9.1 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4471) DUF4834 PF16118.5 CDJ46585.1 - 0.49 11.4 27.5 0.7 10.9 4.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Gaa1 PF04114.14 CDJ46585.1 - 0.7 8.8 4.6 2.5 7.0 0.7 2.4 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component Nucleoside_tran PF01733.18 CDJ46585.1 - 0.93 8.8 3.3 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Nucleoside transporter CLN3 PF02487.17 CDJ46585.1 - 1.1 8.2 10.2 2.9 6.9 1.1 2.8 3 0 0 3 3 3 0 CLN3 protein DUF3381 PF11861.8 CDJ46585.1 - 3.6 7.3 27.5 1.3 8.8 8.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Het-C PF07217.11 CDJ46585.1 - 6.7 5.1 11.3 3.6 6.0 3.5 2.3 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C RskA PF10099.9 CDJ46586.1 - 1.3e-06 28.9 28.3 0.00027 21.3 12.2 2.3 2 0 0 2 2 2 2 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ46586.1 - 5.3e-06 25.6 8.6 6.4e-06 25.4 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex26 PF07163.12 CDJ46586.1 - 0.0089 15.4 9.7 0.014 14.7 9.7 1.3 1 0 0 1 1 1 1 Pex26 protein Presenilin PF01080.17 CDJ46586.1 - 0.011 14.5 5.0 0.013 14.3 5.0 1.2 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CDJ46586.1 - 0.02 14.9 9.1 0.032 14.2 9.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.17 CDJ46586.1 - 0.023 14.9 3.2 0.026 14.7 3.2 1.2 1 0 0 1 1 1 0 DDHD domain Connexin PF00029.19 CDJ46586.1 - 0.032 14.0 1.0 0.04 13.7 1.0 1.1 1 0 0 1 1 1 0 Connexin Band_3_cyto PF07565.13 CDJ46586.1 - 0.033 14.0 1.7 0.039 13.7 1.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AF-4 PF05110.13 CDJ46586.1 - 0.036 12.2 9.5 0.039 12.1 9.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SpoIIP PF07454.11 CDJ46586.1 - 0.061 12.8 3.9 0.081 12.4 3.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Sec62 PF03839.16 CDJ46586.1 - 0.13 11.7 1.8 0.19 11.2 1.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Peroxin-13_N PF04088.13 CDJ46586.1 - 0.17 12.1 2.8 0.32 11.3 2.8 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Miga PF10265.9 CDJ46586.1 - 0.18 10.8 4.4 0.23 10.4 4.4 1.2 1 0 0 1 1 1 0 Mitoguardin EPL1 PF10513.9 CDJ46586.1 - 0.19 12.1 6.6 0.31 11.4 6.6 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like YL1 PF05764.13 CDJ46586.1 - 0.26 11.4 15.1 0.38 10.8 15.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein MDM10 PF12519.8 CDJ46586.1 - 0.37 9.6 4.1 0.46 9.3 4.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF5349 PF17298.2 CDJ46586.1 - 0.5 10.1 8.2 0.9 9.2 8.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5349) EIIBC-GUT_N PF03612.14 CDJ46586.1 - 0.51 10.1 5.6 1 9.0 5.6 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FancD2 PF14631.6 CDJ46586.1 - 0.52 7.7 5.6 0.67 7.3 5.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease PAT1 PF09770.9 CDJ46586.1 - 0.66 8.2 13.4 0.67 8.2 13.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4604 PF15377.6 CDJ46586.1 - 1.1 9.6 13.1 2.2 8.7 13.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) TERB2 PF15101.6 CDJ46586.1 - 1.2 9.2 10.8 1.7 8.7 10.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Neur_chan_memb PF02932.16 CDJ46586.1 - 1.2 9.2 6.4 1.7 8.6 6.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0560 PF10577.9 CDJ46586.1 - 1.5 7.2 10.6 2 6.8 10.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CPSF100_C PF13299.6 CDJ46586.1 - 2 8.6 9.0 0.46 10.7 5.8 1.6 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal EMC3_TMCO1 PF01956.16 CDJ46586.1 - 2.1 8.1 4.6 3 7.6 4.6 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like EOS1 PF12326.8 CDJ46586.1 - 2.1 8.2 4.9 3 7.7 4.9 1.2 1 0 0 1 1 1 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ46586.1 - 2.3 7.1 12.8 2.9 6.7 12.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Thg1C PF14413.6 CDJ46586.1 - 2.6 8.2 9.4 4.4 7.5 9.4 1.3 1 0 0 1 1 1 0 Thg1 C terminal domain DUF3464 PF11947.8 CDJ46586.1 - 2.7 7.7 8.4 5.5 6.7 8.4 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 AIF_C PF14721.6 CDJ46586.1 - 2.7 8.4 6.0 4.8 7.6 6.0 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FAP PF07174.11 CDJ46586.1 - 2.8 7.3 27.9 0.042 13.3 16.6 2.1 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Roughex PF06020.11 CDJ46586.1 - 3 6.9 6.5 3.9 6.5 6.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein RR_TM4-6 PF06459.12 CDJ46586.1 - 3.5 7.4 9.5 4.9 6.9 9.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1980 PF09323.10 CDJ46586.1 - 4 7.3 6.9 2 8.3 3.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Spt20 PF12090.8 CDJ46586.1 - 4.1 6.9 30.6 4 7.0 29.4 1.5 2 0 0 2 2 1 0 Spt20 family V_ATPase_I PF01496.19 CDJ46586.1 - 4.9 5.0 8.2 6.3 4.6 8.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XRCC4 PF06632.12 CDJ46586.1 - 5.4 5.8 11.3 7.3 5.3 11.3 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 MAJIN PF15077.6 CDJ46586.1 - 5.6 6.7 7.2 7.8 6.2 7.2 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Baculo_PP31 PF05311.11 CDJ46586.1 - 6.4 6.2 9.9 8.9 5.7 9.9 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) AAA PF00004.29 CDJ46587.1 - 2.5e-86 286.8 0.0 8e-44 149.3 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ46587.1 - 1.7e-23 82.2 12.8 1.4e-13 50.4 0.6 3.4 3 1 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 CDJ46587.1 - 1.6e-17 63.4 0.5 3.8e-17 62.2 0.5 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 CDJ46587.1 - 3.4e-12 46.8 0.0 5.5e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CDJ46587.1 - 3.5e-12 46.3 0.0 0.00015 21.6 0.0 3.5 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ46587.1 - 6.5e-12 46.2 0.2 0.00089 19.7 0.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CDJ46587.1 - 1.1e-11 44.8 0.1 1.1e-06 28.7 0.0 3.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CDJ46587.1 - 1.3e-10 41.6 0.0 5.2e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 CDJ46587.1 - 5.2e-10 39.0 0.0 1.3e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 CDJ46587.1 - 3.5e-09 37.1 0.1 0.0005 20.4 0.0 3.5 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 CDJ46587.1 - 5.3e-08 32.4 0.0 0.0027 17.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 CDJ46587.1 - 2.7e-07 31.2 0.0 0.013 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CDJ46587.1 - 5.4e-07 30.0 0.0 0.011 16.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 CDJ46587.1 - 6.7e-07 28.9 0.7 0.041 13.3 0.1 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CDJ46587.1 - 9.8e-07 28.9 0.0 0.0017 18.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 CDJ46587.1 - 1.1e-06 28.6 0.1 0.00057 19.8 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 CDJ46587.1 - 5.5e-06 26.1 3.5 0.74 9.4 0.1 4.0 3 1 1 4 4 4 2 AAA domain ATPase PF06745.13 CDJ46587.1 - 2.1e-05 24.0 0.1 2.7 7.3 0.0 3.3 2 1 1 3 3 3 1 KaiC AAA_7 PF12775.7 CDJ46587.1 - 2.2e-05 24.1 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 CDJ46587.1 - 2.2e-05 24.3 0.1 0.19 11.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 CDJ46587.1 - 3.2e-05 24.2 0.0 0.37 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CDJ46587.1 - 4.5e-05 23.3 0.0 0.047 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CDJ46587.1 - 5.4e-05 23.2 0.1 0.21 11.5 0.0 3.2 2 1 1 3 3 3 2 NACHT domain ATPase_2 PF01637.18 CDJ46587.1 - 6.7e-05 22.9 0.1 1 9.2 0.0 3.2 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_17 PF13207.6 CDJ46587.1 - 8.2e-05 23.0 0.1 0.2 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CDJ46587.1 - 8.5e-05 23.1 0.0 0.38 11.3 0.0 2.8 2 1 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 CDJ46587.1 - 0.00017 21.3 0.0 0.18 11.5 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain TsaE PF02367.17 CDJ46587.1 - 0.00019 21.5 0.0 1 9.4 0.0 2.9 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 CDJ46587.1 - 0.00027 20.1 0.0 0.59 9.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 CDJ46587.1 - 0.00047 19.4 0.0 0.95 8.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.12 CDJ46587.1 - 0.0012 18.2 0.0 0.88 8.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 CDJ46587.1 - 0.0018 17.5 0.0 0.39 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 CDJ46587.1 - 0.003 17.4 0.0 3.5 7.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CDJ46587.1 - 0.0031 17.0 0.2 2.1 7.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activ_2 PF14532.6 CDJ46587.1 - 0.0059 16.7 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 CDJ46587.1 - 0.007 16.1 0.0 0.49 10.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CDJ46587.1 - 0.0073 16.2 0.0 2.3 8.1 0.0 2.8 2 1 1 3 3 2 1 Rad17 P-loop domain DUF2075 PF09848.9 CDJ46587.1 - 0.0092 15.3 0.0 0.83 8.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 CDJ46587.1 - 0.013 15.5 0.7 14 5.5 0.0 3.8 3 1 0 4 4 3 0 NTPase AAA_30 PF13604.6 CDJ46587.1 - 0.019 14.7 0.0 3.9 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CDJ46587.1 - 0.027 14.8 1.0 8.6 6.7 0.1 3.3 4 0 0 4 4 2 0 AAA domain KAP_NTPase PF07693.14 CDJ46587.1 - 0.028 13.6 0.1 2.4 7.3 0.0 3.0 2 2 2 4 4 4 0 KAP family P-loop domain Bac_DnaA PF00308.18 CDJ46587.1 - 0.039 13.8 0.0 11 5.8 0.0 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_11 PF13086.6 CDJ46587.1 - 0.046 13.5 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 CDJ46587.1 - 0.047 13.8 0.3 21 5.2 0.0 3.0 3 0 0 3 3 3 0 Shikimate kinase AAA_29 PF13555.6 CDJ46587.1 - 0.07 12.9 0.0 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 CDJ46587.1 - 0.072 12.8 0.1 9 6.0 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase HIT PF01230.23 CDJ46589.1 - 1.2e-22 80.4 0.0 1.9e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDJ46589.1 - 5.6e-10 39.7 0.0 7.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Pkinase PF00069.25 CDJ46590.1 - 7.4e-38 130.4 0.0 3.7e-12 46.2 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ46590.1 - 1.2e-20 73.9 0.0 4.6e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ46590.1 - 8.5e-08 31.2 0.0 0.011 15.2 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDJ46590.1 - 1.4e-06 28.7 0.0 0.17 12.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ46590.1 - 6e-06 25.8 0.2 0.13 12.3 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CDJ46590.1 - 6e-05 22.4 0.8 0.21 11.2 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDJ46590.1 - 0.0017 18.2 0.1 0.1 12.4 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair Lipase_3 PF01764.25 CDJ46591.1 - 1.9e-18 66.7 0.0 3.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ46591.1 - 0.0032 18.1 0.3 0.0032 18.1 0.3 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family WD40 PF00400.32 CDJ46592.1 - 5.2e-08 33.4 0.0 0.00064 20.5 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF3138 PF11336.8 CDJ46592.1 - 0.12 11.0 0.5 0.15 10.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) HAUS-augmin3 PF14932.6 CDJ46592.1 - 0.47 10.0 4.0 0.85 9.1 2.5 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 NOZZLE PF08744.10 CDJ46593.1 - 0.027 14.0 0.3 0.038 13.5 0.3 1.2 1 0 0 1 1 1 0 Plant transcription factor NOZZLE RskA PF10099.9 CDJ46593.1 - 0.15 12.4 18.6 0.23 11.7 18.6 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ46593.1 - 0.99 10.4 9.2 2.5 9.1 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ46593.1 - 5.1 5.8 7.9 6 5.5 7.9 1.1 1 0 0 1 1 1 0 Presenilin Dfp1_Him1_M PF08630.10 CDJ46593.1 - 6.4 7.0 9.1 3.5 7.8 0.5 2.1 2 0 0 2 2 2 0 Dfp1/Him1, central region Med15 PF09606.10 CDJ46594.1 - 0.031 13.0 39.2 0.064 11.9 39.2 1.5 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ46594.1 - 0.22 11.1 46.4 0.066 12.8 15.8 3.0 3 0 0 3 3 3 0 Spt20 family RAB3GAP2_N PF14655.6 CDJ46594.1 - 1.1 8.4 14.8 1.8 7.7 2.9 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus EIF4E-T PF10477.9 CDJ46594.1 - 1.5 7.6 21.7 2.4 6.9 21.7 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Ndc1_Nup PF09531.10 CDJ46594.1 - 1.6 7.3 25.4 0.39 9.3 22.1 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Peroxin-13_N PF04088.13 CDJ46594.1 - 1.9 8.8 6.7 6.7 7.0 0.2 3.1 3 0 0 3 3 3 0 Peroxin 13, N-terminal region ASFV_J13L PF05568.11 CDJ46594.1 - 2.2 8.0 10.2 9 6.0 5.5 2.5 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF4834 PF16118.5 CDJ46594.1 - 2.7 9.0 22.3 2.8 8.9 1.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) DUF775 PF05603.12 CDJ46594.1 - 3.9 7.0 20.6 0.22 11.0 6.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Het-C PF07217.11 CDJ46594.1 - 6.5 5.2 8.1 0.51 8.8 0.5 2.0 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C Connexin PF00029.19 CDJ46594.1 - 8.3 6.1 8.8 6.3 6.5 0.4 3.0 3 0 0 3 3 3 0 Connexin Utp14 PF04615.13 CDJ46595.1 - 9 4.7 60.8 15 4.0 60.8 1.3 1 0 0 1 1 1 0 Utp14 protein SR-25 PF10500.9 CDJ46596.1 - 0.0042 16.7 5.2 0.0042 16.7 5.2 5.0 5 0 0 5 5 5 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ46596.1 - 0.0057 16.3 48.3 0.01 15.5 20.3 3.2 3 0 0 3 3 3 2 Spt20 family LMBR1 PF04791.16 CDJ46596.1 - 1.3 7.9 2.1 2.2 7.1 2.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_23 PF13476.6 CDJ46596.1 - 2.8 8.4 12.9 0.1 13.1 1.1 2.3 2 0 0 2 2 2 0 AAA domain eIF-3_zeta PF05091.12 CDJ46596.1 - 7.5 5.4 15.8 3.4 6.5 8.1 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RskA PF10099.9 CDJ46597.1 - 0.21 11.9 18.5 0.3 11.4 18.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF5423 PF17461.2 CDJ46597.1 - 1.7 7.4 9.9 1.9 7.2 9.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5423) HA2 PF04408.23 CDJ46597.1 - 6.7 7.0 9.4 8.5 6.7 9.4 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) MAJIN PF15077.6 CDJ46597.1 - 8.4 6.1 17.5 8.8 6.0 17.5 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein PAP1 PF08601.10 CDJ46598.1 - 0.0011 18.8 1.1 0.0011 18.8 1.1 15.1 7 6 6 13 13 13 1 Transcription factor PAP1 RskA PF10099.9 CDJ46598.1 - 0.0013 19.1 3.6 0.0013 19.1 3.6 24.0 5 5 11 17 17 17 3 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ46598.1 - 0.0024 17.2 1.2 0.0024 17.2 1.2 13.6 7 4 4 12 12 12 3 Sin-like protein conserved region SARAF PF06682.12 CDJ46598.1 - 0.016 14.8 0.3 0.016 14.8 0.3 15.0 10 5 4 14 14 14 0 SOCE-associated regulatory factor of calcium homoeostasis TAF4 PF05236.14 CDJ46598.1 - 0.74 9.5 0.0 0.74 9.5 0.0 18.6 6 6 8 15 15 15 0 Transcription initiation factor TFIID component TAF4 family Tropomyosin PF00261.20 CDJ46599.1 - 0.00013 21.5 45.4 0.00013 21.5 45.4 3.8 2 1 1 3 3 3 1 Tropomyosin DUF3584 PF12128.8 CDJ46599.1 - 0.0013 16.4 8.3 0.0013 16.4 8.3 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 CDJ46599.1 - 0.0017 18.4 33.1 0.029 14.4 0.0 4.8 3 1 2 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus Microtub_bd PF16796.5 CDJ46599.1 - 0.0039 17.1 0.1 0.0039 17.1 0.1 2.8 3 0 0 3 3 3 1 Microtubule binding DUF1664 PF07889.12 CDJ46599.1 - 0.0052 16.8 10.5 0.0052 16.8 10.5 5.3 3 1 1 5 5 5 1 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 CDJ46599.1 - 0.0066 16.5 26.4 0.0066 16.5 26.4 5.5 3 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.11 CDJ46599.1 - 0.014 15.2 14.2 0.014 15.2 14.2 7.6 2 2 6 8 8 7 0 Phage minor structural protein GP20 Cnn_1N PF07989.11 CDJ46599.1 - 0.015 15.4 1.6 0.015 15.4 1.6 7.1 4 3 2 6 6 4 0 Centrosomin N-terminal motif 1 DUF2203 PF09969.9 CDJ46599.1 - 0.034 14.8 3.9 0.034 14.8 3.9 6.0 2 2 3 6 6 6 0 Uncharacterized conserved protein (DUF2203) Filament PF00038.21 CDJ46599.1 - 0.064 12.8 74.2 0.12 11.9 7.6 5.4 2 1 3 5 5 5 0 Intermediate filament protein DUF4795 PF16043.5 CDJ46599.1 - 0.11 12.1 0.2 0.11 12.1 0.2 5.3 2 2 2 4 4 3 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 CDJ46599.1 - 0.11 11.3 81.0 0.021 13.7 9.2 3.9 2 1 2 4 4 4 0 Spc7 kinetochore protein DUF4407 PF14362.6 CDJ46599.1 - 0.13 11.6 83.5 0.076 12.4 31.4 4.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 CDJ46599.1 - 0.52 9.1 79.6 0.05 12.5 49.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF812) IFT57 PF10498.9 CDJ46599.1 - 1.8 7.4 54.3 0.31 10.0 7.2 3.4 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.9 CDJ46599.1 - 2.7 8.3 65.2 0.31 11.4 15.9 6.6 4 2 4 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 CDJ46599.1 - 3.2 7.8 50.3 0.38 10.8 17.1 5.0 3 2 2 5 5 5 0 Laminin Domain II SHE3 PF17078.5 CDJ46599.1 - 5 6.8 51.8 5.5 6.6 4.4 4.2 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 Golgin_A5 PF09787.9 CDJ46599.1 - 8.5 5.7 73.1 0.7 9.3 8.3 4.3 2 1 3 5 5 5 0 Golgin subfamily A member 5 RskA PF10099.9 CDJ46600.1 - 0.043 14.1 8.8 0.68 10.2 8.8 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA OMPdecase PF00215.24 CDJ46600.1 - 0.087 12.4 2.2 0.11 12.1 2.2 1.1 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF3853 PF12964.7 CDJ46600.1 - 0.13 12.5 4.9 1.3 9.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) DUF4834 PF16118.5 CDJ46600.1 - 0.14 13.2 12.6 0.12 13.3 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MecA PF05389.12 CDJ46600.1 - 0.14 11.8 4.0 0.25 10.9 0.5 2.0 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Presenilin PF01080.17 CDJ46600.1 - 0.15 10.8 8.3 0.19 10.5 8.3 1.1 1 0 0 1 1 1 0 Presenilin PIP5K PF01504.18 CDJ46600.1 - 0.16 11.2 4.9 0.2 10.9 4.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SARAF PF06682.12 CDJ46600.1 - 0.28 10.8 12.0 0.35 10.5 12.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CDH1_2_SANT_HL1 PF18375.1 CDJ46600.1 - 0.34 11.6 4.6 0.33 11.6 0.6 2.1 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Conotoxin PF02950.17 CDJ46600.1 - 0.46 11.5 10.0 2.4 9.2 2.8 2.2 2 0 0 2 2 2 0 Conotoxin DUF3464 PF11947.8 CDJ46600.1 - 0.49 10.1 8.5 0.28 10.9 1.4 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 EphA2_TM PF14575.6 CDJ46600.1 - 1 10.3 7.6 3.2 8.7 1.4 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CLN3 PF02487.17 CDJ46600.1 - 1 8.3 3.8 1.3 7.9 3.8 1.1 1 0 0 1 1 1 0 CLN3 protein DUF3506 PF12014.8 CDJ46600.1 - 1.1 9.2 6.2 1 9.4 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) Ctr PF04145.15 CDJ46600.1 - 1.1 9.8 3.0 1.6 9.4 3.0 1.3 1 0 0 1 1 1 0 Ctr copper transporter family EOS1 PF12326.8 CDJ46600.1 - 1.2 9.0 3.1 1.7 8.5 0.2 1.9 2 0 0 2 2 2 0 N-glycosylation protein GEN1_C PF18380.1 CDJ46600.1 - 2.5 9.0 10.9 4.4 8.2 10.9 1.5 1 1 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain LRRC37AB_C PF14914.6 CDJ46600.1 - 3.1 7.7 11.8 1.3 8.9 1.6 2.1 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain ALMT PF11744.8 CDJ46600.1 - 3.2 6.5 5.2 3.8 6.2 5.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter ANAPC_CDC26 PF10471.9 CDJ46600.1 - 4.5 8.2 32.1 1.3 9.9 13.4 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF775 PF05603.12 CDJ46600.1 - 4.8 6.7 13.7 0.19 11.2 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Rpp20 PF12328.8 CDJ46600.1 - 5.2 7.0 11.8 2 8.3 4.5 2.1 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P WRNPLPNID PF15017.6 CDJ46600.1 - 7.2 7.6 12.7 3 8.8 3.8 2.2 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box EIIBC-GUT_N PF03612.14 CDJ46600.1 - 9.4 5.9 9.6 2.4 7.9 2.7 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus NESP55 PF06390.12 CDJ46601.1 - 0.00016 21.3 12.7 0.0002 21.1 12.7 1.1 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) SpoIIP PF07454.11 CDJ46601.1 - 0.037 13.5 5.8 0.032 13.7 5.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Trypan_PARP PF05887.11 CDJ46601.1 - 0.084 12.9 13.8 0.15 12.0 13.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Presenilin PF01080.17 CDJ46601.1 - 0.11 11.2 4.9 0.093 11.5 4.9 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CDJ46601.1 - 0.12 10.7 8.0 0.1 10.9 8.0 1.0 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.7 CDJ46601.1 - 0.23 11.3 9.7 0.25 11.1 9.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein TAF4 PF05236.14 CDJ46601.1 - 0.26 11.0 16.2 0.3 10.8 16.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF2151 PF10221.9 CDJ46601.1 - 0.27 9.8 5.6 0.24 9.9 5.6 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DDHD PF02862.17 CDJ46601.1 - 0.45 10.6 2.9 0.46 10.6 2.9 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 CDJ46601.1 - 0.64 9.2 3.6 0.54 9.4 3.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4637 PF15470.6 CDJ46601.1 - 1.6 8.4 11.4 2.4 7.9 11.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Eapp_C PF10238.9 CDJ46601.1 - 1.8 8.6 6.6 2.3 8.3 6.6 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein MMU163 PF17119.5 CDJ46601.1 - 2.3 7.3 6.9 3.2 6.9 6.9 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis NPR3 PF03666.13 CDJ46601.1 - 2.3 6.9 10.4 2.4 6.8 10.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CPSF100_C PF13299.6 CDJ46601.1 - 2.8 8.1 10.0 4 7.6 10.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Sec62 PF03839.16 CDJ46601.1 - 5.8 6.4 10.4 6.6 6.2 10.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SLC12 PF03522.15 CDJ46601.1 - 6.1 5.8 6.8 6.5 5.7 6.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4746 PF15928.5 CDJ46601.1 - 6.7 6.0 12.2 7.2 5.9 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FKS1_dom1 PF14288.6 CDJ46602.1 - 0.067 13.5 0.5 0.067 13.5 0.5 2.0 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 ORC_WH_C PF18137.1 CDJ46602.1 - 0.35 10.9 11.3 0.45 10.6 11.3 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF4820 PF16091.5 CDJ46602.1 - 0.65 9.3 12.2 0.79 9.0 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Glypican PF01153.19 CDJ46602.1 - 0.86 8.4 11.9 0.98 8.2 11.9 1.0 1 0 0 1 1 1 0 Glypican DUF2828 PF11443.8 CDJ46602.1 - 1.3 7.1 13.3 1.4 6.9 13.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) AXIN1_TNKS_BD PF16646.5 CDJ46602.1 - 2.4 9.1 11.3 1.1 10.3 0.6 2.1 1 1 1 2 2 2 0 Axin-1 tankyrase binding domain CCDC53 PF10152.9 CDJ46602.1 - 2.9 8.3 15.3 4.1 7.8 15.3 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PIP5K PF01504.18 CDJ46602.1 - 4.5 6.4 11.0 5.6 6.1 11.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Presenilin PF01080.17 CDJ46602.1 - 5.4 5.7 17.9 5.8 5.6 17.9 1.0 1 0 0 1 1 1 0 Presenilin MecA PF05389.12 CDJ46603.1 - 0.0023 17.6 0.2 0.0028 17.3 0.2 1.0 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) RAB3GAP2_N PF14655.6 CDJ46603.1 - 0.0073 15.6 4.8 0.007 15.7 4.8 1.0 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Oleosin PF01277.17 CDJ46603.1 - 0.031 14.0 0.1 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 Oleosin Glt_symporter PF03616.14 CDJ46603.1 - 0.048 12.3 0.5 0.057 12.1 0.5 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter RskA PF10099.9 CDJ46603.1 - 0.19 12.0 15.7 0.3 11.4 15.7 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ46603.1 - 0.37 9.5 3.7 0.35 9.6 3.7 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ46603.1 - 0.39 11.7 6.6 0.62 11.1 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AIF_C PF14721.6 CDJ46603.1 - 0.4 11.0 3.1 0.71 10.2 3.1 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Activator_LAG-3 PF11498.8 CDJ46603.1 - 0.48 9.3 26.9 0.13 11.2 23.3 1.8 2 0 0 2 2 2 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ46603.1 - 0.56 10.1 25.2 0.7 9.8 25.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GPP34 PF05719.11 CDJ46603.1 - 3.4 7.7 9.8 3.5 7.6 8.5 1.5 1 1 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) DUF2232 PF09991.9 CDJ46603.1 - 4.2 6.5 4.0 5 6.2 4.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) eIF3_subunit PF08597.10 CDJ46604.1 - 5.1e-05 23.3 7.4 5.1e-05 23.3 7.4 4.4 2 1 2 4 4 4 1 Translation initiation factor eIF3 subunit SPX PF03105.19 CDJ46604.1 - 0.00022 21.3 7.1 0.00022 21.3 7.1 3.2 3 0 0 3 3 3 1 SPX domain RNA_pol_Rpc4 PF05132.14 CDJ46604.1 - 0.00022 21.7 1.5 0.00022 21.7 1.5 4.6 4 2 0 4 4 4 1 RNA polymerase III RPC4 DXP_reductoisom PF02670.16 CDJ46605.1 - 1.6e-15 57.9 0.2 1.9e-15 57.7 0.2 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.12 CDJ46605.1 - 3e-05 24.1 0.2 5.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Secretin_N_2 PF07655.13 CDJ46605.1 - 0.11 13.0 13.3 0.16 12.5 13.3 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Macoilin PF09726.9 CDJ46605.1 - 0.34 9.4 1.5 0.28 9.7 1.5 1.1 1 0 0 1 1 1 0 Macoilin family X PF00739.19 CDJ46605.1 - 1.9 8.6 5.9 2.6 8.2 5.9 1.2 1 0 0 1 1 1 0 Trans-activation protein X Ribosomal_L9_N PF01281.19 CDJ46606.1 - 1.7e-07 30.7 0.1 3.2e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DUF2722 PF10846.8 CDJ46606.1 - 0.004 16.2 7.4 0.004 16.2 7.4 5.8 5 1 0 5 5 5 1 Protein of unknown function (DUF2722) DUF4207 PF13904.6 CDJ46607.1 - 6.9 6.3 49.2 0.42 10.3 9.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Zip PF02535.22 CDJ46608.1 - 0.066 12.4 5.4 0.019 14.2 1.0 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter OATP PF03137.20 CDJ46608.1 - 3.1 6.0 7.2 8 4.6 0.1 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Endostatin PF06482.11 CDJ46608.1 - 3.3 7.1 31.0 1.4 8.3 0.6 3.5 3 1 0 3 3 3 0 Collagenase NC10 and Endostatin EPL1 PF10513.9 CDJ46608.1 - 9.1 6.6 26.7 0.22 11.9 3.3 3.6 4 0 0 4 4 4 0 Enhancer of polycomb-like TFB6 PF17110.5 CDJ46609.1 - 1.4 8.6 8.1 1.4 8.6 8.1 1.0 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Coilin_N PF15862.5 CDJ46609.1 - 4.5 7.1 17.9 5.2 6.9 17.9 1.2 1 0 0 1 1 1 0 Coilin N-terminus DUF2722 PF10846.8 CDJ46609.1 - 4.6 6.1 34.0 4.3 6.2 34.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) G0-G1_switch_2 PF15103.6 CDJ46609.1 - 7.4 7.1 11.3 8.4 6.9 11.3 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 FAM176 PF14851.6 CDJ46609.1 - 7.9 6.1 9.8 8.1 6.1 9.8 1.1 1 0 0 1 1 1 0 FAM176 family DivIC PF04977.15 CDJ46609.1 - 9 6.1 19.1 12 5.8 19.1 1.3 1 0 0 1 1 1 0 Septum formation initiator Cytochrom_C PF00034.21 CDJ46610.1 - 2.1e-06 28.8 0.1 2.2e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 Cytochrome c SUIM_assoc PF16619.5 CDJ46610.1 - 0.0036 17.3 4.1 0.0063 16.6 4.1 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Cytochrome_CBB3 PF13442.6 CDJ46610.1 - 0.0076 16.6 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CDJ46610.1 - 0.012 15.3 0.1 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c-550 domain Spt20 PF12090.8 CDJ46610.1 - 0.071 12.7 4.5 0.095 12.3 4.5 1.1 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ46610.1 - 1.9 7.6 7.2 2.6 7.1 7.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Rcd1 PF04078.13 CDJ46611.1 - 5e-13 49.0 5.8 7.8e-13 48.3 0.0 2.6 2 0 0 2 2 2 1 Cell differentiation family, Rcd1-like GIDA PF01134.22 CDJ46612.1 - 4e-35 121.7 24.4 3.8e-27 95.4 0.5 3.7 2 1 2 4 4 4 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CDJ46612.1 - 2.9e-05 23.4 2.2 0.0038 16.5 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF2722 PF10846.8 CDJ46612.1 - 0.0022 17.0 0.8 0.0022 17.0 0.8 6.3 4 2 0 5 5 5 2 Protein of unknown function (DUF2722) SPX PF03105.19 CDJ46612.1 - 0.012 15.5 44.9 0.055 13.4 13.3 3.2 2 1 1 3 3 3 0 SPX domain 2-Hacid_dh_C PF02826.19 CDJ46612.1 - 0.015 14.7 0.1 0.015 14.7 0.1 3.9 5 0 0 5 5 5 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 CDJ46612.1 - 0.069 12.4 5.4 0.15 11.3 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF2207 PF09972.9 CDJ46612.1 - 0.38 9.5 4.2 0.88 8.3 0.0 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Pyr_redox PF00070.27 CDJ46612.1 - 1.1 9.8 4.3 1.9 9.1 2.7 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF755 PF05501.11 CDJ46613.1 - 0.016 15.4 14.7 0.016 15.4 14.7 7.9 4 2 2 6 6 6 0 Domain of unknown function (DUF755) eIF-3_zeta PF05091.12 CDJ46613.1 - 0.99 8.3 18.5 2.3 7.1 8.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sporozoite_P67 PF05642.11 CDJ46615.1 - 0.78 7.7 3.7 0.68 7.9 3.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apt1 PF10351.9 CDJ46617.1 - 2.1 7.1 30.5 2.5 6.8 30.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TAP42 PF04177.12 CDJ46618.1 - 8.1e-56 189.5 0.1 1e-55 189.1 0.1 1.1 1 0 0 1 1 1 1 TAP42-like family Apt1 PF10351.9 CDJ46618.1 - 1.4 7.7 6.9 0.13 11.1 2.2 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ46618.1 - 7.1 5.1 7.7 11 4.4 7.7 1.2 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 CDJ46619.1 - 7.4e-23 80.4 7.4 1.8e-05 25.4 0.0 6.7 7 1 0 7 7 7 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CDJ46619.1 - 6.3e-16 58.5 0.0 1.5e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Coatomer WD associated region ANAPC4_WD40 PF12894.7 CDJ46619.1 - 7.3e-05 23.0 0.0 2.3 8.6 0.0 4.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain RskA PF10099.9 CDJ46619.1 - 0.00028 21.2 5.6 0.00028 21.2 5.6 4.9 2 2 1 4 4 3 1 Anti-sigma-K factor rskA Ndc1_Nup PF09531.10 CDJ46619.1 - 0.039 12.7 16.9 0.059 12.1 16.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ46619.1 - 0.18 10.6 30.2 0.29 9.8 30.2 1.3 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ46619.1 - 0.4 7.8 20.4 0.52 7.4 20.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAGA-Tad1 PF12767.7 CDJ46619.1 - 0.41 10.3 19.7 0.67 9.7 19.7 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.9 CDJ46619.1 - 1.1 7.5 50.5 1.7 6.8 50.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 XRN_M PF17846.1 CDJ46619.1 - 1.3 7.9 18.6 2 7.3 18.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain RR_TM4-6 PF06459.12 CDJ46619.1 - 2.6 7.8 24.4 4.9 6.9 24.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CAML PF14963.6 CDJ46619.1 - 3 7.9 10.4 4.9 7.2 10.4 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand CDC45 PF02724.14 CDJ46619.1 - 4.1 5.6 20.2 6.2 5.0 20.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RskA PF10099.9 CDJ46620.1 - 0.017 15.4 10.6 0.017 15.4 10.6 2.0 1 1 1 2 2 1 0 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 CDJ46620.1 - 0.02 14.0 18.4 0.024 13.7 18.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2828 PF11443.8 CDJ46620.1 - 0.025 12.7 18.3 0.027 12.6 18.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Gti1_Pac2 PF09729.9 CDJ46620.1 - 0.026 14.6 13.6 0.028 14.5 13.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family OATP PF03137.20 CDJ46620.1 - 0.037 12.3 5.8 0.052 11.8 5.8 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SpoIIP PF07454.11 CDJ46620.1 - 0.038 13.5 15.0 0.041 13.3 15.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FAM76 PF16046.5 CDJ46620.1 - 0.052 12.9 16.9 0.056 12.8 16.9 1.1 1 0 0 1 1 1 0 FAM76 protein Connexin PF00029.19 CDJ46620.1 - 0.055 13.2 15.1 0.063 13.0 15.1 1.1 1 0 0 1 1 1 0 Connexin eIF-3_zeta PF05091.12 CDJ46620.1 - 0.061 12.3 21.0 0.063 12.3 21.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF913 PF06025.12 CDJ46620.1 - 0.069 12.1 9.5 0.073 12.0 9.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Serinc PF03348.15 CDJ46620.1 - 0.072 12.0 10.4 0.079 11.9 10.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) NPR3 PF03666.13 CDJ46620.1 - 0.075 11.8 13.5 0.08 11.7 13.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 CDJ46620.1 - 0.078 12.0 16.6 0.077 12.0 16.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ46620.1 - 0.08 12.8 18.7 0.089 12.6 18.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 CDJ46620.1 - 0.1 12.1 17.3 0.1 12.1 17.3 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Tim54 PF11711.8 CDJ46620.1 - 0.11 11.3 15.9 0.11 11.3 15.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM60A PF15396.6 CDJ46620.1 - 0.11 12.4 14.1 0.14 12.1 14.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF3295 PF11702.8 CDJ46620.1 - 0.19 11.1 17.1 0.2 11.0 17.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) TFIIA PF03153.13 CDJ46620.1 - 0.2 11.6 48.5 0.25 11.3 48.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1764 PF08576.10 CDJ46620.1 - 0.24 12.3 12.0 0.35 11.8 12.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CDC45 PF02724.14 CDJ46620.1 - 0.28 9.4 14.1 0.3 9.3 14.1 1.0 1 0 0 1 1 1 0 CDC45-like protein PPL5 PF18168.1 CDJ46620.1 - 0.29 10.4 12.0 0.3 10.3 12.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DDHD PF02862.17 CDJ46620.1 - 0.31 11.2 14.2 0.39 10.9 14.2 1.2 1 0 0 1 1 1 0 DDHD domain LAP1C PF05609.12 CDJ46620.1 - 0.31 10.1 21.8 0.32 10.0 21.8 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PAT1 PF09770.9 CDJ46620.1 - 0.32 9.2 39.2 0.3 9.3 39.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2464 PF10240.9 CDJ46620.1 - 0.36 10.3 11.9 0.4 10.2 11.9 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 SID-1_RNA_chan PF13965.6 CDJ46620.1 - 0.37 9.1 7.7 0.37 9.2 7.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BORG_CEP PF14957.6 CDJ46620.1 - 0.38 11.9 13.1 0.45 11.7 13.1 1.1 1 0 0 1 1 1 0 Cdc42 effector Neur_chan_memb PF02932.16 CDJ46620.1 - 0.42 10.6 15.1 0.42 10.6 15.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ46620.1 - 0.44 9.6 14.0 0.47 9.5 14.0 1.1 1 0 0 1 1 1 0 CLN3 protein Endostatin PF06482.11 CDJ46620.1 - 0.44 10.0 21.5 0.49 9.8 21.5 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Peptidase_S64 PF08192.11 CDJ46620.1 - 0.45 8.9 13.9 0.47 8.9 13.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 CAF1 PF04857.20 CDJ46620.1 - 0.46 9.6 11.7 0.52 9.4 11.7 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Folliculin PF11704.8 CDJ46620.1 - 0.47 10.3 10.8 0.52 10.2 10.8 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DDRGK PF09756.9 CDJ46620.1 - 0.54 9.8 24.8 0.66 9.5 24.8 1.1 1 0 0 1 1 1 0 DDRGK domain Zip PF02535.22 CDJ46620.1 - 0.59 9.3 15.5 0.62 9.2 15.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ46620.1 - 0.76 8.5 25.9 0.85 8.3 25.9 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 CDJ46620.1 - 0.77 8.5 14.5 0.83 8.4 14.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Cellulose_synt PF03552.14 CDJ46620.1 - 0.79 8.1 5.4 0.76 8.2 5.4 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF4050 PF13259.6 CDJ46620.1 - 0.85 9.9 14.9 0.93 9.8 14.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Hid1 PF12722.7 CDJ46620.1 - 0.91 7.6 17.9 1 7.4 17.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PIP5K PF01504.18 CDJ46620.1 - 1.1 8.4 17.2 1.3 8.2 17.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase MDM10 PF12519.8 CDJ46620.1 - 1.1 8.0 19.2 1.3 7.8 19.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Otopetrin PF03189.13 CDJ46620.1 - 1.2 7.9 13.7 1.3 7.7 13.7 1.1 1 0 0 1 1 1 0 Otopetrin CSG2 PF16965.5 CDJ46620.1 - 1.2 8.0 9.2 1.3 7.9 9.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Folate_carrier PF01770.18 CDJ46620.1 - 1.2 7.8 9.8 1.5 7.5 9.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier Membralin PF09746.9 CDJ46620.1 - 1.4 7.9 11.6 1.5 7.8 11.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein Bul1_N PF04425.12 CDJ46620.1 - 1.4 7.6 16.3 1.5 7.5 16.3 1.0 1 0 0 1 1 1 0 Bul1 N terminus Spem1 PF15670.5 CDJ46620.1 - 1.5 8.3 18.9 1.9 8.0 18.9 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 FAM176 PF14851.6 CDJ46620.1 - 1.5 8.5 11.6 2.4 7.8 11.6 1.4 1 0 0 1 1 1 0 FAM176 family HemX PF04375.14 CDJ46620.1 - 1.5 8.0 38.5 1.8 7.8 38.5 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Ribonuc_P_40 PF08584.11 CDJ46620.1 - 1.7 7.9 13.3 2 7.7 13.3 1.0 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Band_3_cyto PF07565.13 CDJ46620.1 - 1.9 8.2 20.3 2 8.1 20.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain VIR_N PF15912.5 CDJ46620.1 - 1.9 8.0 12.5 2.3 7.8 12.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Rrn6 PF10214.9 CDJ46620.1 - 1.9 6.9 21.7 1.9 6.9 21.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor UPF0560 PF10577.9 CDJ46620.1 - 1.9 6.9 28.0 2.4 6.5 28.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FliP PF00813.20 CDJ46620.1 - 2 8.3 8.7 2.2 8.1 8.7 1.1 1 0 0 1 1 1 0 FliP family V_ATPase_I PF01496.19 CDJ46620.1 - 2 6.2 24.4 2.4 6.0 24.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HCO3_cotransp PF00955.21 CDJ46620.1 - 2.1 7.1 8.5 2.2 7.0 8.5 1.1 1 0 0 1 1 1 0 HCO3- transporter family Lin-8 PF03353.15 CDJ46620.1 - 2.1 7.8 23.7 2.2 7.7 23.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TYW3 PF02676.14 CDJ46620.1 - 2.2 7.6 12.2 2.2 7.6 12.2 1.2 1 0 0 1 1 1 0 Methyltransferase TYW3 DUF2126 PF09899.9 CDJ46620.1 - 2.5 6.1 13.3 2.6 6.0 13.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Macoilin PF09726.9 CDJ46620.1 - 2.5 6.5 18.0 2.9 6.4 18.0 1.1 1 0 0 1 1 1 0 Macoilin family Exonuc_VII_L PF02601.15 CDJ46620.1 - 2.7 7.5 21.5 2.9 7.4 21.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CobT PF06213.12 CDJ46620.1 - 2.7 7.3 26.8 3.4 7.0 26.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT STAC2_u1 PF16664.5 CDJ46620.1 - 3.6 8.1 15.3 4.6 7.7 15.3 1.1 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 CCSAP PF15748.5 CDJ46620.1 - 3.6 7.7 25.8 4.2 7.5 25.8 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Trp_oprn_chp PF09534.10 CDJ46620.1 - 3.6 7.3 13.7 21 4.9 13.2 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ureide_permease PF07168.11 CDJ46620.1 - 3.6 6.2 8.9 4.7 5.9 8.9 1.3 1 0 0 1 1 1 0 Ureide permease DUF4638 PF15472.6 CDJ46620.1 - 5.5 6.6 16.9 6.5 6.4 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) O-antigen_lig PF13425.6 CDJ46620.1 - 6 5.5 10.4 6.8 5.4 10.4 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4045 PF13254.6 CDJ46620.1 - 6 6.4 18.8 6.4 6.3 18.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) LMBR1 PF04791.16 CDJ46620.1 - 6.9 5.4 12.1 7.4 5.4 12.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein CD20 PF04103.15 CDJ46620.1 - 7.3 6.7 8.6 41 4.2 8.6 1.9 1 1 0 1 1 1 0 CD20-like family Hydin_ADK PF17213.3 CDJ46620.1 - 8.3 6.6 18.5 9.1 6.5 18.5 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Rtf2 PF04641.12 CDJ46620.1 - 9.5 5.5 19.1 11 5.2 19.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3752 PF12572.8 CDJ46625.1 - 0.00038 21.0 8.1 0.00038 21.0 8.1 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3752) Latarcin PF10279.9 CDJ46625.1 - 3.4 8.1 8.9 1.5 9.3 5.4 2.3 2 0 0 2 2 2 0 Latarcin precursor Actin PF00022.19 CDJ46626.1 - 3.4e-74 249.9 0.0 2.2e-73 247.2 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CDJ46626.1 - 0.12 11.2 0.8 8.3 5.1 0.0 2.9 3 0 0 3 3 3 0 MreB/Mbl protein Dynamitin PF04912.14 CDJ46627.1 - 7.8e-31 107.8 13.5 5.3e-25 88.6 10.4 2.8 1 1 0 2 2 2 2 Dynamitin DUF4995 PF16386.5 CDJ46627.1 - 0.24 11.4 1.7 4.7 7.3 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function zf-C3HC4 PF00097.25 CDJ46628.1 - 6.4e-07 29.1 8.7 1.3e-06 28.2 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ46628.1 - 6.7e-06 25.9 8.5 1.6e-05 24.7 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ46628.1 - 1.2e-05 25.4 11.9 2.5e-05 24.3 11.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CDJ46628.1 - 6.9e-05 22.8 6.9 0.00017 21.5 6.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ46628.1 - 0.00021 21.1 8.0 0.00041 20.1 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ46628.1 - 0.00038 20.7 9.7 0.00079 19.7 9.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 CDJ46628.1 - 0.00078 19.3 3.8 0.0019 18.0 3.8 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CDJ46628.1 - 0.0012 18.8 8.9 0.0069 16.3 9.3 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 CDJ46628.1 - 0.003 17.3 3.9 0.0077 16.0 3.9 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 CDJ46628.1 - 0.063 13.2 7.9 1.5 8.7 8.7 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 CDJ46628.1 - 0.068 13.0 2.8 1.7 8.5 1.2 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 CDJ46628.1 - 0.089 12.9 3.0 0.18 11.9 3.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rsbr_N PF08678.10 CDJ46628.1 - 0.14 12.2 0.0 2.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Rsbr N terminal zf-RING_4 PF14570.6 CDJ46628.1 - 2.3 8.1 13.7 18 5.2 14.1 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Suf PF05843.14 CDJ46628.1 - 2.3 8.1 5.5 3.6 7.5 5.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-H2C2_2 PF13465.6 CDJ46628.1 - 2.5 8.7 6.9 2.5 8.7 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Presenilin PF01080.17 CDJ46631.1 - 0.37 9.5 0.9 0.37 9.5 0.9 1.2 1 0 0 1 1 1 0 Presenilin UPF0239 PF06783.11 CDJ46631.1 - 1.6 9.0 3.3 16 5.8 0.0 3.0 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0239) zf-RING_4 PF14570.6 CDJ46632.1 - 1.2e-19 69.8 10.6 2.2e-19 69.0 10.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CDJ46632.1 - 8.6e-07 28.7 7.9 1.6e-06 27.9 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Torus PF16131.5 CDJ46632.1 - 0.011 16.5 0.5 0.011 16.5 0.5 3.7 3 0 0 3 3 3 0 Torus domain zf-RING_2 PF13639.6 CDJ46632.1 - 0.011 16.0 11.4 0.011 16.0 11.4 1.8 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 CDJ46632.1 - 0.021 14.7 10.5 0.045 13.6 10.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CDJ46632.1 - 0.1 12.4 0.2 3.2 7.7 0.1 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.11 CDJ46632.1 - 0.14 12.1 3.1 0.27 11.2 3.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Rad50_zn_hook PF04423.14 CDJ46632.1 - 0.19 11.6 6.0 0.32 10.9 0.4 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 CDJ46632.1 - 0.35 10.8 9.2 14 5.6 9.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 CDJ46632.1 - 0.5 10.5 3.1 1.5 9.0 3.1 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger UPF0004 PF00919.20 CDJ46633.1 - 2.4e-16 59.6 0.2 4.3e-15 55.5 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 CDJ46633.1 - 8.2e-14 52.3 0.0 2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily SUIM_assoc PF16619.5 CDJ46633.1 - 1 9.5 11.1 0.056 13.5 1.0 2.9 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 E7 PF00527.18 CDJ46633.1 - 7.3 6.9 8.0 1.4 9.2 1.9 2.5 2 0 0 2 2 2 0 E7 protein, Early protein DUF2052 PF09747.9 CDJ46634.1 - 6.6 6.8 38.8 0.21 11.7 21.4 2.6 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Nha1_C PF08619.10 CDJ46635.1 - 0.16 11.2 29.1 0.19 10.9 29.1 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus SOBP PF15279.6 CDJ46635.1 - 0.38 11.3 3.0 0.46 11.1 3.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Spem1 PF15670.5 CDJ46635.1 - 1.1 8.8 13.0 1.2 8.6 13.0 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF908 PF06012.12 CDJ46636.1 - 0.094 12.1 17.3 0.17 11.3 3.1 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF908) CLN3 PF02487.17 CDJ46636.1 - 0.17 10.9 15.4 0.13 11.2 5.2 2.2 2 0 0 2 2 2 0 CLN3 protein Presenilin PF01080.17 CDJ46636.1 - 0.43 9.3 25.6 0.98 8.1 10.7 2.3 2 0 0 2 2 2 0 Presenilin Folliculin PF11704.8 CDJ46636.1 - 0.56 10.1 20.6 0.72 9.7 7.0 2.8 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF913 PF06025.12 CDJ46636.1 - 0.57 9.1 8.8 3.4 6.5 0.5 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SARAF PF06682.12 CDJ46636.1 - 0.67 9.5 28.9 0.14 11.8 10.7 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SLC12 PF03522.15 CDJ46636.1 - 2 7.3 22.0 0.41 9.6 6.3 2.1 2 0 0 2 2 2 0 Solute carrier family 12 PNISR PF15996.5 CDJ46636.1 - 2.2 8.5 34.7 0.36 11.1 12.1 2.8 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR AAA_lid_9 PF17871.1 CDJ46637.1 - 5e-33 113.1 0.6 5e-33 113.1 0.6 3.8 2 1 0 3 3 3 1 AAA lid domain AAA PF00004.29 CDJ46637.1 - 4.7e-12 46.5 0.1 2e-11 44.4 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ46637.1 - 8.6e-08 32.8 0.0 8.6e-08 32.8 0.0 3.9 3 3 1 4 4 3 1 AAA ATPase domain Clp_N PF02861.20 CDJ46637.1 - 3.6e-06 27.0 1.5 1.2e-05 25.3 1.5 2.0 1 0 0 1 1 1 1 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 CDJ46637.1 - 0.00094 19.2 0.5 0.072 13.1 0.3 3.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_tran_CTD PF16326.5 CDJ46637.1 - 0.0032 17.7 6.1 0.0032 17.7 6.1 4.3 3 1 1 4 4 2 1 ABC transporter C-terminal domain ATPase_2 PF01637.18 CDJ46637.1 - 0.005 16.8 1.0 0.91 9.4 0.0 2.8 2 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CDJ46637.1 - 0.0095 16.3 0.0 0.037 14.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 CDJ46637.1 - 0.011 15.6 0.8 0.41 10.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Spt20 PF12090.8 CDJ46637.1 - 0.019 14.6 21.7 0.032 13.8 21.7 1.3 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ46637.1 - 0.028 13.2 3.1 0.041 12.6 3.1 1.2 1 0 0 1 1 1 0 Presenilin RuvB_N PF05496.12 CDJ46637.1 - 0.049 13.4 0.0 0.16 11.7 0.0 1.9 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CDJ46637.1 - 0.055 13.5 0.0 0.32 11.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDJ46637.1 - 0.06 12.9 2.6 4.2 6.9 0.0 3.4 2 1 1 3 3 3 0 AAA domain DUF2722 PF10846.8 CDJ46637.1 - 0.081 11.9 17.5 0.12 11.3 17.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TsaE PF02367.17 CDJ46637.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EIIBC-GUT_N PF03612.14 CDJ46637.1 - 0.26 11.0 6.2 0.59 9.8 6.2 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TFIIA PF03153.13 CDJ46637.1 - 0.4 10.6 23.0 0.015 15.3 16.6 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AAA_18 PF13238.6 CDJ46637.1 - 0.4 11.2 0.0 0.4 11.2 0.0 3.3 3 2 1 4 4 4 0 AAA domain FAM76 PF16046.5 CDJ46637.1 - 0.93 8.8 14.4 0.23 10.8 4.0 2.5 2 1 0 2 2 2 0 FAM76 protein DDHD PF02862.17 CDJ46637.1 - 1 9.5 5.5 0.23 11.6 1.7 1.8 2 0 0 2 2 2 0 DDHD domain Pex14_N PF04695.13 CDJ46637.1 - 5 7.8 15.0 11 6.6 15.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_22 PF13401.6 CDJ46637.1 - 6.7 7.0 9.2 0.61 10.4 0.2 3.7 2 2 1 3 3 2 0 AAA domain ALMT PF11744.8 CDJ46638.1 - 3.6 6.3 39.7 4.8 5.9 39.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter GAGA_bind PF06217.12 CDJ46638.1 - 3.9 7.7 37.8 5.7 7.1 37.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family AF-4 PF05110.13 CDJ46639.1 - 0.025 12.7 13.4 0.028 12.5 13.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ46639.1 - 0.29 10.7 14.1 0.39 10.3 14.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_capsid PF06112.11 CDJ46639.1 - 1.3 9.1 17.1 1.7 8.7 17.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CCDC106 PF15794.5 CDJ46639.1 - 3.5 7.3 4.7 4.3 7.0 4.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Glyco_hydro_9 PF00759.19 CDJ46640.1 - 0.004 16.7 1.7 0.0053 16.2 1.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 baeRF_family10 PF18854.1 CDJ46640.1 - 0.023 15.0 2.9 0.023 15.0 2.9 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 DUF4834 PF16118.5 CDJ46640.1 - 0.054 14.5 5.4 0.18 12.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ46640.1 - 0.065 13.2 13.5 0.015 15.3 2.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CNDH2_M PF16869.5 CDJ46640.1 - 0.15 12.8 4.7 0.56 10.9 0.0 2.4 2 1 0 2 2 2 0 PF16858 Consortin_C PF15281.6 CDJ46640.1 - 2.5 8.1 4.9 1.2 9.1 2.2 1.9 1 1 0 1 1 1 0 Consortin C-terminus DUF2076 PF09849.9 CDJ46640.1 - 3.6 7.6 21.1 1.1 9.3 10.6 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Ctr PF04145.15 CDJ46640.1 - 5.5 7.6 8.5 1.9e+02 2.6 8.5 2.5 1 1 0 1 1 1 0 Ctr copper transporter family SPX PF03105.19 CDJ46641.1 - 0.0014 18.6 16.0 0.002 18.1 16.0 1.4 1 0 0 1 1 1 1 SPX domain NPR3 PF03666.13 CDJ46641.1 - 0.023 13.5 6.0 0.03 13.1 6.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF572 PF04502.13 CDJ46641.1 - 0.24 11.0 6.9 0.32 10.6 6.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Band_3_cyto PF07565.13 CDJ46641.1 - 0.38 10.5 2.6 0.64 9.8 2.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Zip PF02535.22 CDJ46641.1 - 0.45 9.7 4.9 0.61 9.3 4.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ46641.1 - 0.45 9.2 8.0 0.64 8.7 8.0 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ46641.1 - 1.3 6.1 12.9 1.9 5.5 12.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Utp14 PF04615.13 CDJ46641.1 - 2.8 6.4 7.7 3.7 6.0 7.7 1.1 1 0 0 1 1 1 0 Utp14 protein Integrin_alpha PF00357.20 CDJ46643.1 - 0.036 14.1 13.6 67 3.8 0.1 6.4 5 0 0 5 5 5 0 Integrin alpha cytoplasmic region Pentapeptide_2 PF01469.18 CDJ46643.1 - 0.087 12.7 1.0 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) EIF4E-T PF10477.9 CDJ46644.1 - 3.4 6.4 14.5 4.1 6.1 14.5 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4746 PF15928.5 CDJ46645.1 - 0.0023 17.4 10.0 0.0023 17.4 10.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4746) DUF4471 PF14740.6 CDJ46645.1 - 0.17 11.0 11.3 0.012 14.9 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Rxt3 PF08642.10 CDJ46645.1 - 0.27 12.0 7.1 0.52 11.1 2.1 2.5 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 SpoIIP PF07454.11 CDJ46645.1 - 0.28 10.6 18.7 0.032 13.7 10.2 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 CDJ46645.1 - 0.38 9.5 17.0 0.0095 14.8 8.4 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pex14_N PF04695.13 CDJ46645.1 - 0.46 11.1 19.1 0.32 11.6 15.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF913 PF06025.12 CDJ46645.1 - 0.58 9.1 7.0 0.17 10.9 3.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF4834 PF16118.5 CDJ46645.1 - 1.1 10.3 19.2 2.4 9.2 14.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Otopetrin PF03189.13 CDJ46645.1 - 1.6 7.5 3.5 0.94 8.2 1.5 1.6 2 0 0 2 2 2 0 Otopetrin CPSF100_C PF13299.6 CDJ46645.1 - 1.7 8.8 15.4 0.78 9.9 10.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Cellulose_synt PF03552.14 CDJ46645.1 - 2.1 6.7 6.7 1.5 7.2 3.8 1.9 2 0 0 2 2 2 0 Cellulose synthase Alph_Pro_TM PF09608.10 CDJ46645.1 - 2.4 7.9 7.9 4.8 6.9 7.9 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TMEM51 PF15345.6 CDJ46645.1 - 2.5 7.9 18.8 0.031 14.1 10.3 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 Presenilin PF01080.17 CDJ46645.1 - 3.7 6.2 18.5 0.87 8.3 14.2 1.9 2 0 0 2 2 2 0 Presenilin SLC12 PF03522.15 CDJ46645.1 - 3.9 6.4 16.6 0.21 10.6 8.9 2.0 2 0 0 2 2 2 0 Solute carrier family 12 FAM91_C PF14648.6 CDJ46645.1 - 4.4 6.0 10.8 0.41 9.4 5.4 1.8 2 0 0 2 2 2 0 FAM91 C-terminus CCDC53 PF10152.9 CDJ46645.1 - 4.6 7.7 17.2 3.4 8.1 13.2 2.5 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex RNA_pol_Rpc4 PF05132.14 CDJ46645.1 - 5.4 7.4 16.4 1.3 9.4 9.7 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Eapp_C PF10238.9 CDJ46645.1 - 6.6 6.8 19.1 0.45 10.6 10.9 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Neur_chan_memb PF02932.16 CDJ46645.1 - 6.7 6.7 11.5 3.5 7.6 8.4 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.6 CDJ46645.1 - 7.5 4.3 39.7 0.12 10.2 32.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) UPF0560 PF10577.9 CDJ46645.1 - 7.8 4.9 22.4 15 3.9 22.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SUFU_C PF12470.8 CDJ46645.1 - 8.2 6.4 13.8 15 5.5 8.5 2.2 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain EPL1 PF10513.9 CDJ46645.1 - 9 6.7 19.8 0.78 10.1 10.9 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Pet20 PF08692.10 CDJ46645.1 - 9.6 6.9 10.7 17 6.1 4.8 2.5 2 0 0 2 2 2 0 Mitochondrial protein Pet20 RR_TM4-6 PF06459.12 CDJ46645.1 - 10 5.9 23.0 0.15 11.9 11.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SR-25 PF10500.9 CDJ46646.1 - 0.0018 17.9 21.0 0.0018 17.9 21.0 1.7 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ46646.1 - 0.01 15.9 35.4 0.014 15.4 35.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 CDJ46646.1 - 0.034 13.8 9.6 0.048 13.3 9.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.9 CDJ46646.1 - 0.64 8.8 10.2 0.77 8.5 10.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.15 CDJ46646.1 - 1.6 8.2 13.3 2.9 7.3 0.9 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF3408 PF11888.8 CDJ46646.1 - 5.4 7.2 8.8 0.86 9.7 4.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) TFIIA PF03153.13 CDJ46648.1 - 0.00096 19.3 31.7 0.0015 18.6 31.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit OmpH PF03938.14 CDJ46648.1 - 0.012 16.0 24.8 0.016 15.5 24.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CDJ46648.1 - 0.089 12.1 18.2 0.11 11.8 18.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med15 PF09606.10 CDJ46648.1 - 0.74 8.4 29.1 1.2 7.7 29.1 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Nop53 PF07767.11 CDJ46648.1 - 2.7 7.3 18.7 4 6.7 18.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DivIC PF04977.15 CDJ46648.1 - 5.8 6.8 17.7 10 6.0 17.7 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4834 PF16118.5 CDJ46648.1 - 8.1 7.5 16.5 4.4 8.3 9.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ46648.1 - 8.5 6.1 8.3 16 5.2 8.3 1.4 1 0 0 1 1 1 0 Connexin TAF4 PF05236.14 CDJ46649.1 - 0.0021 17.8 6.7 0.0021 17.8 6.7 4.1 2 1 1 4 4 4 1 Transcription initiation factor TFIID component TAF4 family TCP PF03634.13 CDJ46649.1 - 0.0022 18.6 20.2 0.0022 18.6 20.2 4.7 3 1 0 3 3 3 1 TCP family transcription factor Utp14 PF04615.13 CDJ46649.1 - 0.01 14.5 44.8 0.0073 15.0 17.7 2.2 2 0 0 2 2 2 0 Utp14 protein DUF572 PF04502.13 CDJ46649.1 - 0.12 12.0 42.0 0.87 9.1 12.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) Ribosomal_60s PF00428.19 CDJ46649.1 - 0.41 11.3 54.0 0.048 14.2 19.1 3.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein AF-4 PF05110.13 CDJ46649.1 - 1.9 6.4 64.9 0.24 9.5 37.9 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein UFD1 PF03152.14 CDJ46650.1 - 8.1e-13 48.2 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 CDJ46650.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 SR-25 PF10500.9 CDJ46650.1 - 0.27 10.8 8.9 0.45 10.1 8.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ArfGap PF01412.18 CDJ46651.1 - 0.037 14.1 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Peptidase_M18 PF02127.15 CDJ46652.1 - 1e-50 172.8 0.0 1.1e-50 172.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Exonuc_VII_L PF02601.15 CDJ46653.1 - 4.3e-05 23.2 2.5 4.3e-05 23.2 2.5 4.4 4 1 0 4 4 4 1 Exonuclease VII, large subunit RskA PF10099.9 CDJ46653.1 - 0.0027 18.0 3.4 0.0027 18.0 3.4 11.9 6 4 4 10 10 10 2 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ46654.1 - 0.00069 18.7 16.5 0.00069 18.7 16.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) AP2 PF00847.20 CDJ46654.1 - 0.55 10.5 0.0 0.55 10.5 0.0 5.5 7 0 0 7 7 7 0 AP2 domain eIF-3_zeta PF05091.12 CDJ46654.1 - 0.87 8.5 19.5 0.26 10.2 11.5 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 CDJ46654.1 - 1.7 8.2 59.6 0.32 10.6 34.0 2.7 3 0 0 3 3 3 0 Spt20 family BSP_II PF05432.11 CDJ46656.1 - 0.00046 20.0 29.5 0.00051 19.8 29.5 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) K_channel_TID PF07941.11 CDJ46656.1 - 0.04 14.4 18.1 0.04 14.4 18.1 6.5 2 1 2 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain SDA1 PF05285.12 CDJ46656.1 - 0.084 12.3 20.0 0.098 12.1 20.0 1.1 1 0 0 1 1 1 0 SDA1 PCM1_C PF15717.5 CDJ46656.1 - 1.9 7.1 17.5 2.3 6.8 17.5 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Nop14 PF04147.12 CDJ46656.1 - 4.7 5.3 19.4 5.9 5.0 19.4 1.2 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 CDJ46656.1 - 6.6 6.2 14.8 7.9 6.0 14.8 1.2 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 CDJ46656.1 - 8.6 5.0 16.5 11 4.7 16.5 1.3 1 0 0 1 1 1 0 Presenilin SspK PF08176.12 CDJ46658.1 - 0.23 11.8 0.0 0.36 11.1 0.0 1.2 1 0 0 1 1 1 0 Small acid-soluble spore protein K family Hydrolase_4 PF12146.8 CDJ46659.1 - 1.3e-16 60.6 0.2 2.6e-09 36.7 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ46659.1 - 1.5e-10 41.2 0.2 3.1e-06 27.0 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ46659.1 - 1.1e-08 35.9 0.0 1.7e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 CDJ46659.1 - 8.7e-08 32.0 0.0 1.6e-05 24.6 0.0 2.8 2 1 1 3 3 3 1 Dienelactone hydrolase family AXE1 PF05448.12 CDJ46659.1 - 9.8e-07 27.7 1.1 0.0032 16.2 0.1 3.2 1 1 2 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 CDJ46659.1 - 3.2e-06 26.8 0.1 0.0033 16.9 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 CDJ46659.1 - 0.00016 21.4 0.0 0.0029 17.3 0.0 2.1 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 CDJ46659.1 - 0.002 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CDJ46659.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S15 PF02129.18 CDJ46659.1 - 0.023 14.3 0.0 3.6 7.1 0.0 2.3 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 CDJ46659.1 - 0.045 13.7 0.0 0.82 9.5 0.0 2.4 1 1 2 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 CDJ46659.1 - 0.048 13.4 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 CDJ46659.1 - 0.05 13.5 0.0 0.19 11.5 0.1 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF818 PF05677.12 CDJ46659.1 - 0.06 12.3 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Thioesterase PF00975.20 CDJ46659.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Adap_comp_sub PF00928.21 CDJ46661.1 - 3.9e-11 42.8 0.0 6.1e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ46661.1 - 0.12 12.3 0.5 0.4 10.6 0.2 1.9 2 0 0 2 2 2 0 Clathrin adaptor complex small chain TFIIA PF03153.13 CDJ46662.1 - 0.56 10.1 63.5 0.61 10.0 13.6 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4577 PF15145.6 CDJ46663.1 - 0.049 13.7 1.9 0.36 10.9 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Pox_A14 PF05767.12 CDJ46663.1 - 0.44 10.7 9.3 0.068 13.3 5.1 1.9 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 TMEM154 PF15102.6 CDJ46663.1 - 4.8 7.1 6.3 29 4.5 2.4 2.5 2 0 0 2 2 2 0 TMEM154 protein family tRNA-synt_1c PF00749.21 CDJ46667.1 - 6.3e-84 281.5 0.3 3.2e-72 243.1 0.0 2.9 2 1 1 3 3 3 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CDJ46667.1 - 4.9e-36 124.2 0.0 2.3e-35 122.0 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain PcfK PF14058.6 CDJ46667.1 - 2 8.7 9.5 17 5.7 0.0 2.4 2 0 0 2 2 2 0 PcfK-like protein HECT PF00632.25 CDJ46668.1 - 4.7e-68 229.9 0.3 5.4e-68 229.7 0.3 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SRAP PF02586.14 CDJ46669.1 - 1.2e-11 44.5 0.0 2.3e-11 43.7 0.0 1.4 2 0 0 2 2 2 1 SOS response associated peptidase (SRAP) Ribosomal_60s PF00428.19 CDJ46669.1 - 0.0086 16.7 5.1 0.013 16.0 5.1 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Apt1 PF10351.9 CDJ46669.1 - 0.23 10.3 6.3 0.2 10.4 6.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.13 CDJ46669.1 - 2.8 8.5 23.0 0.78 10.3 0.4 2.7 3 0 0 3 3 3 0 Secretin N-terminal domain SRAP PF02586.14 CDJ46670.1 - 4.4e-06 26.4 0.8 4.4e-06 26.4 0.8 2.5 1 1 0 2 2 2 1 SOS response associated peptidase (SRAP) VIR_N PF15912.5 CDJ46670.1 - 0.72 9.4 17.2 4.5 6.8 0.1 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal DUF913 PF06025.12 CDJ46670.1 - 1.7 7.6 19.6 0.27 10.2 10.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SUFU_C PF12470.8 CDJ46670.1 - 3.4 7.7 15.6 8.8 6.3 7.6 2.4 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain SID-1_RNA_chan PF13965.6 CDJ46670.1 - 3.6 5.9 11.5 0.56 8.5 6.0 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Vfa1 PF08432.10 CDJ46670.1 - 3.9 7.8 29.8 3.6 7.9 17.5 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PIP5K PF01504.18 CDJ46670.1 - 7.2 5.8 23.8 2.5 7.3 1.4 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Trm112p PF03966.16 CDJ46671.1 - 9.7e-12 45.3 0.7 9.7e-12 45.3 0.7 2.4 2 1 0 2 2 2 1 Trm112p-like protein TERB2 PF15101.6 CDJ46671.1 - 0.33 11.0 27.1 0.54 10.3 5.8 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Pex14_N PF04695.13 CDJ46671.1 - 2.8 8.6 27.5 0.14 12.8 11.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C PF13299.6 CDJ46671.1 - 5.7 7.1 11.6 3.3 7.8 5.6 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Lysine_decarbox PF03641.14 CDJ46672.1 - 4e-17 62.5 0.0 4.8e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase DUF1754 PF08555.10 CDJ46672.1 - 0.39 11.5 2.6 0.55 11.1 2.6 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF515 PF04415.12 CDJ46672.1 - 0.74 8.1 18.8 0.8 8.0 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Macoilin PF09726.9 CDJ46672.1 - 3.4 6.1 12.9 3.7 6.0 12.9 1.0 1 0 0 1 1 1 0 Macoilin family SARAF PF06682.12 CDJ46673.1 - 0.13 11.9 5.9 0.15 11.7 5.9 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis LRRFIP PF09738.9 CDJ46673.1 - 1.6 8.1 10.4 2.1 7.8 10.4 1.1 1 0 0 1 1 1 0 LRRFIP family PI3K_1B_p101 PF10486.9 CDJ46673.1 - 2.7 5.7 7.3 3.2 5.4 7.3 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Apt1 PF10351.9 CDJ46673.1 - 2.8 6.7 7.9 3.4 6.4 7.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ46673.1 - 3 6.5 4.0 3.6 6.2 4.0 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 CDJ46673.1 - 5.3 5.5 8.2 6.1 5.3 8.2 1.2 1 0 0 1 1 1 0 Macoilin family DUF3357 PF11837.8 CDJ46673.1 - 5.3 7.5 12.1 72 3.9 12.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) RSRP PF17069.5 CDJ46673.1 - 5.4 6.5 22.8 7.2 6.1 22.8 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 TMEM151 PF14857.6 CDJ46673.1 - 6 5.7 6.7 7.4 5.4 6.7 1.1 1 0 0 1 1 1 0 TMEM151 family Miga PF10265.9 CDJ46673.1 - 8.7 5.2 8.0 10 5.0 8.0 1.1 1 0 0 1 1 1 0 Mitoguardin YscJ_FliF_C PF08345.11 CDJ46675.1 - 0.06 13.7 11.7 0.075 13.4 11.7 1.2 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal DUF4574 PF15141.6 CDJ46675.1 - 0.063 13.2 0.6 0.063 13.2 0.6 2.3 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 WTX PF09422.10 CDJ46675.1 - 1.4 7.9 11.9 1.4 7.9 11.9 1.0 1 0 0 1 1 1 0 WTX protein ALMT PF11744.8 CDJ46675.1 - 1.7 7.4 13.5 2.1 7.1 13.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 CDJ46675.1 - 2.3 6.9 14.9 2.9 6.6 14.9 1.1 1 0 0 1 1 1 0 Presenilin Conotoxin PF02950.17 CDJ46675.1 - 3.2 8.8 13.4 6.2 7.9 4.9 2.3 2 0 0 2 2 2 0 Conotoxin TAF4 PF05236.14 CDJ46676.1 - 0.0021 17.9 12.6 0.0021 17.9 12.6 13.4 5 3 3 9 9 9 1 Transcription initiation factor TFIID component TAF4 family ArsA_ATPase PF02374.15 CDJ46677.1 - 1.2e-28 100.2 0.1 1.4e-28 100.0 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CDJ46677.1 - 1.7e-10 41.1 0.0 2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CDJ46677.1 - 3.2e-10 40.1 0.1 3.6e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CDJ46677.1 - 3.5e-06 26.7 0.0 3.8e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 CDJ46677.1 - 2.5e-05 23.8 0.1 3.1e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 CDJ46677.1 - 0.00049 19.7 0.0 0.00054 19.5 0.0 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 CDJ46677.1 - 0.00097 18.8 0.1 0.0013 18.4 0.1 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CDJ46677.1 - 0.0012 18.2 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.22 CDJ46677.1 - 0.0015 17.8 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.20 CDJ46677.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase T2SSE PF00437.20 CDJ46677.1 - 0.025 13.7 0.1 0.029 13.5 0.1 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein VirC1 PF07015.11 CDJ46677.1 - 0.029 13.7 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 VirC1 protein NACHT PF05729.12 CDJ46677.1 - 0.037 13.9 0.6 0.064 13.2 0.6 1.3 1 1 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 CDJ46677.1 - 0.044 13.5 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CDJ46677.1 - 0.054 14.0 0.0 0.063 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ46677.1 - 0.081 13.4 0.0 0.097 13.2 0.0 1.1 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 CDJ46677.1 - 0.1 12.1 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 CDJ46677.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_16 PF13191.6 CDJ46677.1 - 0.11 12.9 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.14 CDJ46677.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 CDJ46677.1 - 0.14 12.5 0.1 0.19 12.1 0.1 1.3 1 1 0 1 1 1 0 RNA helicase ResIII PF04851.15 CDJ46677.1 - 0.15 12.0 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MeaB PF03308.16 CDJ46677.1 - 0.16 10.9 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MipZ PF09140.11 CDJ46677.1 - 0.16 11.2 0.1 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 ATPase MipZ PhoH PF02562.16 CDJ46677.1 - 0.19 11.1 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein BAF1_ABF1 PF04684.13 CDJ46678.1 - 1.8 7.5 31.1 2.2 7.2 31.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ANAPC_CDC26 PF10471.9 CDJ46679.1 - 0.00052 20.8 7.1 0.00057 20.7 7.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CDJ46679.1 - 0.0029 17.2 13.9 0.003 17.2 13.9 1.0 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ46679.1 - 0.04 13.9 10.7 0.039 14.0 10.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ46679.1 - 0.096 13.7 1.5 0.095 13.7 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ46679.1 - 0.18 10.7 12.9 0.19 10.7 12.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ46679.1 - 0.22 10.4 17.4 0.21 10.5 17.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF1180 PF06679.12 CDJ46679.1 - 0.68 10.3 5.4 0.72 10.2 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) UPF0560 PF10577.9 CDJ46679.1 - 0.82 8.1 6.2 0.82 8.1 6.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3138 PF11336.8 CDJ46679.1 - 0.98 8.0 10.7 0.97 8.0 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CcmD PF04995.14 CDJ46679.1 - 3.2 7.9 9.3 5.5 7.1 9.3 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Roughex PF06020.11 CDJ46679.1 - 5.1 6.1 9.5 5.8 5.9 9.5 1.0 1 0 0 1 1 1 0 Drosophila roughex protein Ribosomal_L7Ae PF01248.26 CDJ46680.1 - 2.2e-14 52.9 0.0 4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4834 PF16118.5 CDJ46680.1 - 0.06 14.3 0.0 0.06 14.3 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1645 PF07816.11 CDJ46680.1 - 0.063 13.9 16.4 0.14 12.7 8.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Conotoxin PF02950.17 CDJ46680.1 - 0.46 11.5 0.2 0.46 11.5 0.2 2.6 2 1 0 2 2 2 0 Conotoxin CCDC53 PF10152.9 CDJ46680.1 - 0.47 10.9 8.5 0.24 11.8 1.0 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SR-25 PF10500.9 CDJ46680.1 - 0.86 9.2 32.0 0.066 12.8 20.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ46680.1 - 1.6 8.3 18.1 0.74 9.4 6.7 2.2 2 0 0 2 2 2 0 Spt20 family Striatin PF08232.12 CDJ46680.1 - 2 9.0 12.8 2.8 8.5 4.8 2.1 2 0 0 2 2 2 0 Striatin family Sporozoite_P67 PF05642.11 CDJ46680.1 - 4.4 5.3 21.2 0.31 9.1 14.0 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen IMUP PF15761.5 CDJ46681.1 - 3.4 8.4 24.1 1.1 9.9 3.1 2.8 3 0 0 3 3 3 0 Immortalisation up-regulated protein TFIIA PF03153.13 CDJ46681.1 - 8 6.3 46.1 3.9 7.4 30.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SHE3 PF17078.5 CDJ46683.1 - 0.047 13.4 0.6 0.07 12.8 0.6 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF4094 PF13334.6 CDJ46683.1 - 0.21 12.0 1.1 0.55 10.7 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Mto2_bdg PF12808.7 CDJ46683.1 - 0.44 10.9 3.6 1 9.7 2.1 2.2 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region IspD PF01128.19 CDJ46684.1 - 8.1e-15 55.2 16.7 3.5e-11 43.3 3.0 4.8 4 1 1 5 5 5 2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Dehydrin PF00257.19 CDJ46684.1 - 0.0063 17.1 3.7 0.0063 17.1 3.7 5.0 4 1 0 4 4 4 1 Dehydrin KASH PF10541.9 CDJ46684.1 - 0.17 12.1 1.9 0.44 10.9 1.9 1.6 1 0 0 1 1 1 0 Nuclear envelope localisation domain DUF4776 PF16003.5 CDJ46684.1 - 4.3 6.2 16.9 0.21 10.5 10.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) SPX PF03105.19 CDJ46685.1 - 0.15 12.0 8.9 4.5 7.1 8.9 2.1 1 1 0 1 1 1 0 SPX domain DUF4614 PF15391.6 CDJ46685.1 - 7 6.6 18.7 4.6 7.2 8.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DUF1764 PF08576.10 CDJ46686.1 - 1.4e-11 45.2 7.5 1.4e-11 45.2 7.5 2.2 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) SR-25 PF10500.9 CDJ46686.1 - 0.013 15.1 20.2 0.021 14.4 20.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4471 PF14740.6 CDJ46686.1 - 0.24 10.6 8.3 0.015 14.6 2.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4471) Draxin PF15550.6 CDJ46686.1 - 0.68 9.8 17.7 0.85 9.4 17.7 1.1 1 0 0 1 1 1 0 Draxin SOBP PF15279.6 CDJ46686.1 - 0.76 10.3 12.6 0.97 10.0 12.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein ANAPC1 PF12859.7 CDJ46686.1 - 1.5 9.4 5.8 2.4 8.7 5.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Neur_chan_memb PF02932.16 CDJ46686.1 - 2 8.4 12.4 2.4 8.1 12.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 CDJ46686.1 - 2.7 5.0 16.3 3.2 4.7 16.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF966 PF06136.13 CDJ46686.1 - 4.8 6.8 15.8 7.1 6.2 15.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PA26 PF04636.13 CDJ46686.1 - 6.4 5.6 11.3 8.3 5.2 11.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ALMT PF11744.8 CDJ46686.1 - 7.5 5.3 9.8 9.6 4.9 9.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 CDJ46686.1 - 7.8 4.3 9.5 9.7 4.0 9.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mif2_N PF15624.6 CDJ46686.1 - 9.8 6.9 12.3 0.61 10.8 5.3 2.2 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CCSAP PF15748.5 CDJ46686.1 - 9.9 6.2 22.7 13 5.9 22.7 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Cullin PF00888.22 CDJ46689.1 - 1.3e-16 60.4 4.7 7.9e-15 54.5 0.0 2.3 2 1 0 2 2 2 2 Cullin family DUF3446 PF11928.8 CDJ46689.1 - 0.001 19.3 2.3 0.0031 17.8 2.3 1.8 1 0 0 1 1 1 1 Early growth response N-terminal domain SUIM_assoc PF16619.5 CDJ46689.1 - 0.031 14.3 0.9 0.031 14.3 0.9 5.3 2 2 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 IMUP PF15761.5 CDJ46689.1 - 0.041 14.6 5.7 0.13 13.0 5.7 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein SnoaL_4 PF13577.6 CDJ46689.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF1645 PF07816.11 CDJ46689.1 - 0.58 10.7 12.7 0.6 10.7 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) SpoIIP PF07454.11 CDJ46689.1 - 1 8.8 18.4 0.52 9.7 11.1 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Paf1 PF03985.13 CDJ46689.1 - 1.5 7.7 21.9 0.038 13.0 11.7 2.2 2 0 0 2 2 2 0 Paf1 GAGA_bind PF06217.12 CDJ46689.1 - 1.7 8.9 13.5 0.28 11.4 6.9 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family CLN3 PF02487.17 CDJ46689.1 - 1.8 7.5 9.7 2.2 7.3 6.0 2.2 2 0 0 2 2 2 0 CLN3 protein BUD22 PF09073.10 CDJ46690.1 - 9 5.5 34.2 12 5.0 34.2 1.2 1 0 0 1 1 1 0 BUD22 XRN_N PF03159.18 CDJ46691.1 - 4.9e-08 32.7 0.0 4.9e-08 32.7 0.0 4.4 2 2 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus RskA PF10099.9 CDJ46691.1 - 0.00024 21.4 1.8 0.00024 21.4 1.8 5.6 2 1 2 4 4 4 1 Anti-sigma-K factor rskA DUF2367 PF10164.9 CDJ46691.1 - 0.091 13.3 0.1 0.091 13.3 0.1 4.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2367) CDK5_activator PF03261.15 CDJ46691.1 - 7.7 6.0 28.1 2.2 7.7 21.6 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein AAA_6 PF12774.7 CDJ46692.1 - 5.7e-132 439.6 0.0 1.8e-130 434.7 0.0 3.1 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ46692.1 - 1.1e-111 373.8 5.7 1.1e-111 373.8 5.7 3.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CDJ46692.1 - 8.5e-111 371.3 4.0 8.5e-111 371.3 4.0 4.6 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 CDJ46692.1 - 5.7e-68 228.3 0.2 5.7e-68 228.3 0.2 3.6 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 CDJ46692.1 - 4.6e-62 209.7 0.0 3.5e-61 206.8 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CDJ46692.1 - 2.1e-47 161.8 0.5 8.5e-47 159.8 0.5 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CDJ46692.1 - 3.2e-36 124.5 0.0 5e-29 101.1 0.0 5.1 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDJ46692.1 - 2.1e-33 115.4 0.0 4.9e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CDJ46692.1 - 6.4e-31 107.6 11.0 1.2e-30 106.8 11.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CDJ46692.1 - 8.8e-30 103.2 4.1 9.7e-30 103.1 0.0 3.4 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CDJ46692.1 - 7.2e-29 100.6 0.0 3.3e-10 40.1 0.0 6.0 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ46692.1 - 2.3e-15 57.2 0.3 0.013 16.0 0.0 6.3 6 0 0 6 6 5 3 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 CDJ46692.1 - 2.5e-11 43.8 0.0 1.1e-10 41.7 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 CDJ46692.1 - 3.2e-11 43.6 6.4 0.00073 19.8 0.0 7.9 7 2 0 7 7 6 1 AAA domain AAA_16 PF13191.6 CDJ46692.1 - 2.9e-08 34.3 6.3 1.1 9.7 0.0 7.5 5 1 0 5 5 4 1 AAA ATPase domain AAA_18 PF13238.6 CDJ46692.1 - 4.2e-07 30.6 0.2 7.9 7.0 0.0 5.6 5 0 0 5 5 4 0 AAA domain T2SSE PF00437.20 CDJ46692.1 - 1.7e-05 24.0 0.0 0.1 11.6 0.0 3.4 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_25 PF13481.6 CDJ46692.1 - 0.00011 21.9 0.6 0.012 15.2 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.6 CDJ46692.1 - 0.00016 22.0 0.7 0.23 11.8 0.0 5.1 5 0 0 5 5 4 1 AAA domain IstB_IS21 PF01695.17 CDJ46692.1 - 0.0004 20.2 0.4 0.23 11.2 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein TelA PF05816.11 CDJ46692.1 - 0.00048 19.3 5.1 0.00048 19.3 5.1 4.1 4 0 0 4 4 3 1 Toxic anion resistance protein (TelA) TsaE PF02367.17 CDJ46692.1 - 0.0019 18.2 1.4 3 7.8 0.0 4.2 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Asn_synthase PF00733.21 CDJ46692.1 - 0.0023 17.7 1.4 0.0041 16.8 0.1 2.1 2 0 0 2 2 1 1 Asparagine synthase AAA_33 PF13671.6 CDJ46692.1 - 0.0041 17.3 11.6 0.74 10.0 0.0 5.5 6 0 0 6 6 4 1 AAA domain Rad17 PF03215.15 CDJ46692.1 - 0.005 16.8 0.0 19 5.1 0.0 4.4 5 0 0 5 5 4 0 Rad17 P-loop domain MPS2 PF17060.5 CDJ46692.1 - 0.012 14.9 9.6 0.13 11.5 2.3 2.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 RNA_helicase PF00910.22 CDJ46692.1 - 0.015 15.6 0.0 1.1e+02 3.2 0.0 4.9 5 0 0 5 5 4 0 RNA helicase cobW PF02492.19 CDJ46692.1 - 0.025 14.2 0.5 0.22 11.1 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_lid_1 PF17857.1 CDJ46692.1 - 0.036 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA+ lid domain RuvB_N PF05496.12 CDJ46692.1 - 0.053 13.3 0.0 5.9 6.6 0.0 3.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 CDJ46692.1 - 0.063 13.3 1.7 7.4 6.5 0.0 4.2 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 CDJ46692.1 - 0.086 12.2 8.0 6.7 6.0 0.0 4.7 4 1 1 5 5 5 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CDJ46692.1 - 0.23 12.0 6.5 18 5.8 0.0 5.1 5 0 0 5 5 3 0 ABC transporter AAA_24 PF13479.6 CDJ46692.1 - 0.45 10.2 4.1 19 4.9 0.0 3.9 4 0 0 4 4 3 0 AAA domain NBD94 PF16830.5 CDJ46692.1 - 0.46 10.9 6.6 0.34 11.3 2.9 2.8 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH ATG16 PF08614.11 CDJ46692.1 - 0.53 10.5 25.5 4.3 7.5 9.5 3.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 CDJ46692.1 - 2.3 7.5 11.0 0.53 9.6 2.2 2.5 2 0 0 2 2 2 0 FAM76 protein DUF4615 PF15393.6 CDJ46692.1 - 2.4 8.7 7.2 2.3 8.8 0.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) SF1-HH PF16275.5 CDJ46692.1 - 4 7.8 4.7 38 4.7 2.5 3.0 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain Ribosomal_L29 PF00831.23 CDJ46693.1 - 4.9e-18 64.8 4.1 4.9e-18 64.8 4.1 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Ac76 PF05814.11 CDJ46693.1 - 0.12 12.4 4.5 0.2 11.7 0.3 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) TLD PF07534.16 CDJ46694.1 - 2.3e-24 86.2 0.1 8.2e-24 84.4 0.1 1.9 2 0 0 2 2 2 1 TLD Cation_ATPase_N PF00690.26 CDJ46694.1 - 0.06 13.0 0.7 0.26 11.0 0.1 2.3 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus SUI1 PF01253.22 CDJ46695.1 - 7.6e-17 61.6 0.2 1.5e-16 60.7 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Sirohm_synth_M PF14824.6 CDJ46695.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central DUF2722 PF10846.8 CDJ46698.1 - 0.00022 20.3 0.8 0.00029 19.9 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) CRAL_TRIO PF00650.20 CDJ46698.1 - 0.00088 19.0 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain RskA PF10099.9 CDJ46698.1 - 0.0017 18.7 3.9 0.0017 18.7 3.9 3.2 3 0 0 3 3 3 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ46698.1 - 0.005 16.9 2.9 0.005 16.9 2.9 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Fcf1 PF04900.12 CDJ46698.1 - 0.12 12.7 0.3 2.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Fcf1 DUF4834 PF16118.5 CDJ46698.1 - 0.72 10.9 2.4 1.6 9.7 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ46698.1 - 0.91 9.1 18.4 1.6 8.3 18.4 1.3 1 0 0 1 1 1 0 Spt20 family AP2 PF00847.20 CDJ46699.1 - 2e-08 34.3 0.1 2e-08 34.3 0.1 2.3 3 0 0 3 3 3 1 AP2 domain SUIM_assoc PF16619.5 CDJ46699.1 - 1.1e-05 25.4 0.3 1.1e-05 25.4 0.3 3.9 3 1 1 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ46699.1 - 0.0068 16.0 8.8 0.0068 16.0 8.8 3.1 2 1 0 3 3 3 1 Spt20 family DUF4259 PF14078.6 CDJ46699.1 - 1.2 9.9 5.9 4.2 8.1 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) V_ATPase_I PF01496.19 CDJ46699.1 - 2.5 5.9 5.2 3.4 5.5 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LCD1 PF09798.9 CDJ46699.1 - 2.9 6.3 9.4 4 5.8 9.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Hamartin PF04388.12 CDJ46699.1 - 4.9 5.7 32.3 6 5.4 32.3 1.0 1 0 0 1 1 1 0 Hamartin protein Tom5 PF10642.9 CDJ46701.1 - 0.069 13.2 1.5 0.069 13.2 1.5 2.1 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase Mucin PF01456.17 CDJ46702.1 - 0.00026 21.0 10.4 0.00034 20.6 10.4 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Collagen PF01391.18 CDJ46702.1 - 0.014 15.1 12.5 0.023 14.4 12.5 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) RhlB PF12300.8 CDJ46702.1 - 0.018 15.2 5.4 0.021 14.9 5.4 1.1 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Defensin_propep PF00879.18 CDJ46702.1 - 0.028 14.7 0.0 0.028 14.7 0.0 1.9 2 0 0 2 2 2 0 Defensin propeptide HMG_box PF00505.19 CDJ46703.1 - 2.6e-08 34.2 0.6 5.6e-08 33.1 0.3 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ46703.1 - 1.4e-05 25.5 7.7 0.00014 22.4 7.7 2.3 1 1 0 1 1 1 1 HMG-box domain Macoilin PF09726.9 CDJ46703.1 - 0.076 11.6 16.2 0.091 11.3 16.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF4614 PF15391.6 CDJ46703.1 - 2.3 8.2 19.7 5.1 7.0 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Spt20 PF12090.8 CDJ46703.1 - 2.4 7.7 22.7 0.058 13.0 13.2 2.2 2 0 0 2 2 2 0 Spt20 family Kinesin PF00225.23 CDJ46704.1 - 6.2e-35 120.7 11.7 1.7e-23 83.1 0.5 3.5 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ46704.1 - 7.5e-15 55.2 1.6 3.1e-13 49.9 0.5 2.9 3 0 0 3 3 3 2 Microtubule binding Ribosomal_60s PF00428.19 CDJ46704.1 - 4 8.1 7.1 38 5.0 0.0 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Apt1 PF10351.9 CDJ46705.1 - 0.61 8.9 22.6 0.77 8.5 22.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cyt_bd_oxida_II PF02322.15 CDJ46705.1 - 0.87 8.9 5.0 1.1 8.6 5.0 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DNA_pol_phi PF04931.13 CDJ46706.1 - 0.099 10.7 2.8 0.13 10.3 2.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nucleo_P87 PF07267.11 CDJ46706.1 - 0.16 10.8 10.3 0.23 10.3 10.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4770 PF15994.5 CDJ46706.1 - 0.27 11.5 6.8 0.28 11.4 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF2828 PF11443.8 CDJ46706.1 - 0.74 7.8 7.3 1.1 7.3 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ46706.1 - 1.3 7.7 11.1 2.2 7.0 11.1 1.4 1 0 0 1 1 1 0 Presenilin DUF4589 PF15252.6 CDJ46706.1 - 1.6 8.7 10.9 6 6.8 10.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4589) SPICE PF15678.5 CDJ46706.1 - 3.1 7.1 17.0 4.9 6.4 17.0 1.3 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression Secretin_N_2 PF07655.13 CDJ46707.1 - 0.0041 17.6 8.4 0.0041 17.6 8.4 2.4 2 0 0 2 2 2 1 Secretin N-terminal domain LUC7 PF03194.15 CDJ46707.1 - 7.4 6.2 15.3 0.022 14.4 5.6 1.7 2 0 0 2 2 2 0 LUC7 N_terminus eIF-3_zeta PF05091.12 CDJ46708.1 - 0.0042 16.1 8.8 0.0042 16.1 8.8 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SprA-related PF12118.8 CDJ46708.1 - 0.006 15.8 18.5 0.0069 15.6 18.5 1.1 1 0 0 1 1 1 1 SprA-related family RIFIN PF02009.16 CDJ46708.1 - 0.007 16.3 5.9 0.0074 16.2 5.9 1.0 1 0 0 1 1 1 1 Rifin Presenilin PF01080.17 CDJ46708.1 - 0.021 13.6 5.8 0.019 13.8 5.8 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ46708.1 - 0.045 13.7 28.5 0.05 13.6 28.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MecA PF05389.12 CDJ46708.1 - 0.053 13.1 5.5 0.054 13.1 5.5 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DDHD PF02862.17 CDJ46708.1 - 0.055 13.6 5.3 0.052 13.7 5.3 1.1 1 0 0 1 1 1 0 DDHD domain GET2 PF08690.10 CDJ46708.1 - 0.066 12.9 9.8 0.078 12.6 9.8 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Suf PF05843.14 CDJ46708.1 - 0.075 13.0 11.2 0.066 13.2 11.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RskA PF10099.9 CDJ46708.1 - 0.086 13.1 25.1 0.31 11.3 25.1 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ46708.1 - 0.089 13.8 10.8 0.12 13.4 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SID-1_RNA_chan PF13965.6 CDJ46708.1 - 0.099 11.0 0.5 0.1 11.0 0.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Connexin PF00029.19 CDJ46708.1 - 0.12 12.2 2.9 0.11 12.3 2.9 1.2 1 0 0 1 1 1 0 Connexin TMEM51 PF15345.6 CDJ46708.1 - 0.17 11.7 14.5 0.23 11.3 14.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Neur_chan_memb PF02932.16 CDJ46708.1 - 0.18 11.8 2.7 0.16 12.0 2.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 CDJ46708.1 - 0.21 11.5 1.5 0.22 11.4 1.5 1.2 1 0 0 1 1 1 0 N-glycosylation protein Spt20 PF12090.8 CDJ46708.1 - 0.27 10.8 35.8 0.31 10.6 35.8 1.1 1 0 0 1 1 1 0 Spt20 family Serinc PF03348.15 CDJ46708.1 - 0.45 9.4 2.8 0.47 9.3 2.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) V_ATPase_I PF01496.19 CDJ46708.1 - 0.82 7.5 9.4 0.88 7.4 9.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EIIBC-GUT_N PF03612.14 CDJ46708.1 - 2.5 7.8 10.3 3.9 7.2 10.3 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_S15 PF02129.18 CDJ46708.1 - 3 7.4 14.3 4.5 6.8 14.3 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FAM150 PF15129.6 CDJ46708.1 - 3.4 7.8 14.3 4.8 7.3 14.3 1.2 1 0 0 1 1 1 0 FAM150 family Conotoxin PF02950.17 CDJ46708.1 - 6.2 7.9 7.9 15 6.7 7.9 1.7 1 0 0 1 1 1 0 Conotoxin TERB2 PF15101.6 CDJ46708.1 - 7.5 6.5 17.4 8.8 6.3 17.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Herpes_UL52 PF03121.15 CDJ46709.1 - 1.3e-05 25.0 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Hamartin PF04388.12 CDJ46709.1 - 0.15 10.7 9.3 0.17 10.5 9.3 1.1 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 CDJ46709.1 - 0.53 10.2 43.6 0.78 9.7 43.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 CDJ46710.1 - 0.0049 15.8 14.3 0.005 15.7 14.3 1.1 1 0 0 1 1 1 1 Androgen receptor HemX PF04375.14 CDJ46710.1 - 0.033 13.5 13.7 0.035 13.4 13.7 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TFIIA PF03153.13 CDJ46710.1 - 0.036 14.1 22.4 0.041 13.9 22.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK2AP PF09806.9 CDJ46710.1 - 0.096 12.7 15.5 0.11 12.5 15.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein AF-4 PF05110.13 CDJ46710.1 - 0.11 10.6 25.9 0.12 10.4 25.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FAM163 PF15069.6 CDJ46710.1 - 0.12 12.9 6.7 0.15 12.5 6.7 1.1 1 0 0 1 1 1 0 FAM163 family GREB1 PF15782.5 CDJ46710.1 - 0.12 9.4 17.5 0.13 9.3 17.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDJ46710.1 - 0.14 10.7 19.3 0.16 10.5 19.3 1.0 1 0 0 1 1 1 0 Macoilin family CSRNP_N PF16019.5 CDJ46710.1 - 0.14 12.1 11.3 0.17 11.8 11.3 1.0 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus FAM176 PF14851.6 CDJ46710.1 - 0.21 11.2 4.7 0.28 10.8 4.7 1.3 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 CDJ46710.1 - 0.22 11.2 13.4 0.26 11.0 13.4 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Spt20 PF12090.8 CDJ46710.1 - 0.26 10.9 31.5 0.32 10.6 31.5 1.1 1 0 0 1 1 1 0 Spt20 family PNISR PF15996.5 CDJ46710.1 - 0.3 11.4 14.1 0.34 11.1 14.1 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Plasmodium_Vir PF05795.11 CDJ46710.1 - 0.42 10.0 12.9 0.5 9.7 12.9 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM60A PF15396.6 CDJ46710.1 - 0.46 10.4 12.7 0.55 10.2 12.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 CDJ46710.1 - 0.47 9.2 16.6 0.5 9.1 16.6 1.0 1 0 0 1 1 1 0 Presenilin MscS_TM PF12794.7 CDJ46710.1 - 0.55 9.0 3.0 0.64 8.8 3.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2464 PF10240.9 CDJ46710.1 - 0.6 9.6 11.3 0.73 9.3 11.3 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 PI3K_1B_p101 PF10486.9 CDJ46710.1 - 0.61 7.8 13.9 0.7 7.6 13.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Roughex PF06020.11 CDJ46710.1 - 0.65 9.0 9.4 0.66 9.0 9.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Menin PF05053.13 CDJ46710.1 - 0.66 8.3 13.2 0.72 8.1 13.2 1.0 1 0 0 1 1 1 0 Menin FAM70 PF14967.6 CDJ46710.1 - 0.76 9.2 9.3 0.92 8.9 9.3 1.0 1 0 0 1 1 1 0 FAM70 protein Miga PF10265.9 CDJ46710.1 - 0.85 8.5 17.2 0.87 8.5 17.2 1.0 1 0 0 1 1 1 0 Mitoguardin CPSF100_C PF13299.6 CDJ46710.1 - 0.9 9.7 7.7 1.1 9.4 7.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Arteri_nsp7a PF16749.5 CDJ46710.1 - 0.96 9.6 5.1 1.4 9.1 5.1 1.2 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha DUF1645 PF07816.11 CDJ46710.1 - 1 9.9 17.8 1.3 9.6 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Zip PF02535.22 CDJ46710.1 - 1.2 8.3 6.8 1.4 8.1 6.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 CDJ46710.1 - 1.3 8.0 14.0 1.4 7.9 14.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Mem_trans PF03547.18 CDJ46710.1 - 1.3 7.3 10.5 1.4 7.2 10.5 1.0 1 0 0 1 1 1 0 Membrane transport protein PAT1 PF09770.9 CDJ46710.1 - 1.7 6.8 15.9 1.9 6.6 15.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.6 CDJ46710.1 - 1.8 6.4 13.7 1.6 6.5 13.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Lin-8 PF03353.15 CDJ46710.1 - 1.8 8.0 18.4 2.2 7.8 18.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ureide_permease PF07168.11 CDJ46710.1 - 2 7.1 5.1 2.3 6.9 5.1 1.2 1 0 0 1 1 1 0 Ureide permease ALMT PF11744.8 CDJ46710.1 - 2 7.1 14.5 2.2 7.0 14.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter NEMP PF10225.9 CDJ46710.1 - 2.3 7.8 6.3 2.6 7.7 6.3 1.1 1 0 0 1 1 1 0 NEMP family MPM1 PF17234.2 CDJ46710.1 - 2.5 8.3 18.0 3.2 8.0 18.0 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Kinesin_assoc PF16183.5 CDJ46710.1 - 2.9 8.0 6.3 3.3 7.8 6.3 1.1 1 0 0 1 1 1 0 Kinesin-associated DivIC PF04977.15 CDJ46710.1 - 2.9 7.7 12.0 4.3 7.2 12.0 1.3 1 0 0 1 1 1 0 Septum formation initiator Ndc1_Nup PF09531.10 CDJ46710.1 - 3 6.4 16.4 3.2 6.3 16.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 CDJ46710.1 - 3.4 7.5 20.5 3.6 7.4 20.5 1.0 1 0 0 1 1 1 0 SPX domain SDP_N PF12278.8 CDJ46710.1 - 3.4 7.8 17.6 4.7 7.4 17.6 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal Peptidase_S64 PF08192.11 CDJ46710.1 - 3.9 5.8 20.3 4.4 5.7 20.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4407 PF14362.6 CDJ46710.1 - 4.2 6.6 9.4 4.3 6.6 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.7 CDJ46710.1 - 4.3 5.3 16.2 4.8 5.2 16.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec62 PF03839.16 CDJ46710.1 - 4.4 6.8 8.8 5.1 6.5 8.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 EPL1 PF10513.9 CDJ46710.1 - 4.8 7.5 15.6 5.9 7.3 15.6 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like XRN_M PF17846.1 CDJ46710.1 - 5 6.0 8.6 5.5 5.8 8.6 1.0 1 0 0 1 1 1 0 Xrn1 helical domain NPR3 PF03666.13 CDJ46710.1 - 5.2 5.8 17.6 5.6 5.6 17.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CLN3 PF02487.17 CDJ46710.1 - 5.5 5.9 8.8 6.1 5.8 8.8 1.0 1 0 0 1 1 1 0 CLN3 protein MCM_bind PF09739.9 CDJ46710.1 - 5.8 5.2 16.9 7.1 5.0 16.9 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DLIC PF05783.11 CDJ46710.1 - 9.6 4.9 10.0 11 4.7 10.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RAP1 PF07218.11 CDJ46711.1 - 0.17 10.1 10.9 0.15 10.3 10.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BAF1_ABF1 PF04684.13 CDJ46711.1 - 0.2 10.7 14.7 0.24 10.4 14.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ46711.1 - 0.51 10.3 31.0 0.63 10.0 31.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Helicase_RecD PF05127.14 CDJ46711.1 - 0.81 9.5 7.8 1.2 9.0 7.8 1.2 1 0 0 1 1 1 0 Helicase ST7 PF04184.12 CDJ46711.1 - 0.9 7.9 7.4 1.2 7.6 7.4 1.1 1 0 0 1 1 1 0 ST7 protein MMS19_N PF14500.6 CDJ46711.1 - 1.3 8.6 6.9 1.7 8.2 6.9 1.1 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II PAT1 PF09770.9 CDJ46711.1 - 1.6 6.9 17.6 1.6 6.9 17.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GET2 PF08690.10 CDJ46711.1 - 2.5 7.7 13.9 3.1 7.4 13.9 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 SprA-related PF12118.8 CDJ46711.1 - 3 6.9 30.1 4.6 6.3 30.1 1.2 1 0 0 1 1 1 0 SprA-related family Peptidase_S15 PF02129.18 CDJ46711.1 - 7.2 6.1 13.6 9.9 5.7 13.6 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4131 PF13567.6 CDJ46712.1 - 0.0025 17.5 0.1 0.0079 15.9 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4131) O-antigen_lig PF13425.6 CDJ46712.1 - 0.11 11.3 0.0 0.11 11.3 0.0 2.8 3 0 0 3 3 3 0 O-antigen ligase like membrane protein RR_TM4-6 PF06459.12 CDJ46713.1 - 8.7 6.1 31.9 10 5.8 31.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ46713.1 - 9.9 4.3 26.5 11 4.2 26.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Mitofilin PF09731.9 CDJ46714.1 - 1 8.1 17.4 1.3 7.8 17.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein EBP50_C PF09007.11 CDJ46715.1 - 0.055 14.5 1.6 13 6.8 0.0 2.4 2 0 0 2 2 2 0 EBP50, C-terminal EIF4E-T PF10477.9 CDJ46715.1 - 1.1 8.0 9.2 1.3 7.7 9.2 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RskA PF10099.9 CDJ46716.1 - 0.15 12.3 11.3 1.8 8.9 11.3 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF2457 PF10446.9 CDJ46716.1 - 0.7 9.0 13.8 0.85 8.7 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SPX PF03105.19 CDJ46716.1 - 1.9 8.4 22.7 2.6 7.9 22.7 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ46716.1 - 2.1 7.1 20.9 3 6.6 20.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIA PF03153.13 CDJ46716.1 - 2.5 8.0 17.1 3.2 7.6 17.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Upf2 PF04050.14 CDJ46716.1 - 5.2 7.8 7.5 1.1 10.0 0.1 2.3 2 1 0 2 2 2 0 Up-frameshift suppressor 2 ubiquitin PF00240.23 CDJ46719.1 - 7.3e-21 73.7 0.0 7.3e-21 73.7 0.0 1.5 2 0 0 2 2 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ46719.1 - 6.2e-08 32.4 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CDJ46719.1 - 1.3e-05 25.2 1.1 2.9e-05 24.1 1.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 CDJ46719.1 - 3.1e-05 23.8 0.1 6.7e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF2407 PF10302.9 CDJ46719.1 - 0.00025 21.6 0.7 0.00051 20.6 0.7 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 CDJ46719.1 - 0.0009 19.3 3.4 0.01 15.9 0.0 2.7 3 0 0 3 3 2 1 HOIP UBA domain pair CUE PF02845.16 CDJ46719.1 - 0.0038 16.9 0.0 0.0094 15.6 0.0 1.7 1 0 0 1 1 1 1 CUE domain TBK1_ULD PF18396.1 CDJ46719.1 - 0.02 14.8 0.0 0.02 14.8 0.0 1.7 2 0 0 2 2 1 0 TANK binding kinase 1 ubiquitin-like domain Pex14_N PF04695.13 CDJ46719.1 - 0.033 14.9 3.4 0.033 14.9 3.4 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UBA_4 PF14555.6 CDJ46719.1 - 0.056 13.3 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain Ubiquitin_2 PF14560.6 CDJ46719.1 - 0.06 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Spt20 PF12090.8 CDJ46719.1 - 2.6 7.6 20.8 0.084 12.5 13.8 1.9 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ46719.1 - 4.8 6.0 17.0 0.71 8.7 12.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ46719.1 - 4.9 7.0 31.8 4.6 7.1 24.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ46719.1 - 7.1 6.8 25.7 54 3.9 0.1 3.0 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HEPN_LA2681 PF18733.1 CDJ46720.1 - 0.053 12.8 0.5 6.7 6.0 0.2 2.2 2 0 0 2 2 2 0 LA2681-like HEPN YfcL PF08891.11 CDJ46720.1 - 0.11 12.9 2.7 0.48 10.8 0.1 2.6 2 0 0 2 2 2 0 YfcL protein SUIM_assoc PF16619.5 CDJ46720.1 - 0.55 10.3 14.0 0.052 13.6 7.7 2.5 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ46720.1 - 0.57 10.1 13.1 0.82 9.6 13.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CT_C_D PF02682.16 CDJ46720.1 - 1.1 9.0 6.4 11 5.6 3.0 2.4 1 1 1 2 2 2 0 Carboxyltransferase domain, subdomain C and D Calc_CGRP_IAPP PF00214.19 CDJ46720.1 - 2.5 8.5 7.2 4.3 7.7 4.2 2.5 2 1 0 2 2 2 0 Calcitonin / CGRP / IAPP family PAP_central PF04928.17 CDJ46720.1 - 6.2 5.7 6.4 1.5 7.7 2.8 1.7 2 1 0 2 2 2 0 Poly(A) polymerase central domain DUF4786 PF16027.5 CDJ46721.1 - 1.7 9.2 5.2 15 6.2 2.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4786) GN3L_Grn1 PF08701.11 CDJ46722.1 - 1.7e-19 69.6 9.8 1.7e-19 69.6 9.8 3.5 3 1 1 4 4 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 CDJ46722.1 - 2e-15 56.8 0.0 1.3e-13 51.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ46722.1 - 5.7e-08 32.4 0.0 1.1e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDJ46722.1 - 0.00044 20.2 0.8 0.035 14.0 0.6 2.9 3 0 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 CDJ46722.1 - 0.0048 17.0 3.8 0.85 9.7 0.1 3.8 3 1 0 4 4 4 1 Dynamin family AAA_16 PF13191.6 CDJ46722.1 - 0.011 16.2 0.1 0.011 16.2 0.1 3.3 2 2 1 3 3 2 0 AAA ATPase domain GTP_EFTU PF00009.27 CDJ46722.1 - 0.017 14.7 0.0 0.51 9.8 0.0 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 CDJ46722.1 - 0.039 12.9 0.3 0.1 11.6 0.3 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvA_C PF07499.13 CDJ46722.1 - 0.044 14.2 1.1 0.17 12.4 0.1 2.5 2 0 0 2 2 2 0 RuvA, C-terminal domain AAA_18 PF13238.6 CDJ46722.1 - 0.14 12.7 0.4 2 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain GRAB PF10375.9 CDJ46722.1 - 0.5 10.3 1.4 1.8 8.6 0.1 2.2 2 0 0 2 2 2 0 GRIP-related Arf-binding domain PDZ_3 PF17815.1 CDJ46723.1 - 2.1e-27 95.8 0.8 1e-26 93.6 0.4 2.0 2 0 0 2 2 2 1 PDZ domain Trypsin_2 PF13365.6 CDJ46723.1 - 4.1e-18 66.7 0.8 1.1e-17 65.3 0.8 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CDJ46723.1 - 3.8e-12 46.5 0.1 7.4e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 CDJ46723.1 - 6.3e-05 23.2 2.4 0.00041 20.6 0.0 2.8 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 CDJ46723.1 - 0.029 14.2 2.6 0.15 12.0 0.1 3.1 3 0 0 3 3 3 0 PDZ domain Peptidase_S46 PF10459.9 CDJ46723.1 - 0.14 10.7 0.1 0.33 9.5 0.1 1.6 1 0 0 1 1 1 0 Peptidase S46 DUF2870 PF11069.8 CDJ46726.1 - 3.9e-22 78.5 1.3 7.4e-22 77.5 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) ubiquitin PF00240.23 CDJ46726.1 - 0.14 11.9 0.3 12 5.7 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin family Folate_carrier PF01770.18 CDJ46727.1 - 0.08 11.7 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Reduced folate carrier DUF4051 PF13260.6 CDJ46727.1 - 0.089 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) KH_1 PF00013.29 CDJ46729.1 - 0.21 11.4 0.3 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 KH domain Chalcone_2 PF16035.5 CDJ46729.1 - 1.1 9.0 4.5 3 7.6 4.5 1.7 1 0 0 1 1 1 0 Chalcone isomerase like Spore_III_AB PF09548.10 CDJ46729.1 - 3.5 7.7 4.5 8.7 6.4 4.5 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PAN_4 PF14295.6 CDJ46730.1 - 0.14 12.1 0.7 1 9.3 0.1 2.6 2 0 0 2 2 2 0 PAN domain T3SSipB PF16535.5 CDJ46730.1 - 0.88 10.0 5.2 0.26 11.7 0.3 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB PHM7_cyt PF14703.6 CDJ46731.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DnaJ PF00226.31 CDJ46732.1 - 1.9e-08 34.3 0.1 6.8e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain DUF5612 PF18462.1 CDJ46732.1 - 0.078 12.8 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) TPR_2 PF07719.17 CDJ46732.1 - 1.1 9.6 5.1 2.3 8.6 0.9 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L6 PF00347.23 CDJ46733.1 - 9.7e-23 80.6 1.0 4e-12 46.6 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 CENP-W PF15510.6 CDJ46733.1 - 0.06 13.6 0.5 3.6 7.9 0.1 2.4 2 0 0 2 2 2 0 CENP-W protein DUF2228 PF10228.9 CDJ46734.1 - 0.061 13.0 0.6 0.087 12.6 0.6 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) VTC PF09359.10 CDJ46735.1 - 1.1e-73 248.1 0.0 1.6e-73 247.5 0.0 1.2 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 CDJ46735.1 - 9.2e-07 29.2 3.3 8.2e-06 26.2 0.5 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 CDJ46735.1 - 6.2e-05 23.1 4.4 0.0084 16.1 4.4 2.3 1 1 0 1 1 1 1 SPX domain TMEM52 PF14979.6 CDJ46735.1 - 0.13 12.2 1.2 0.62 10.0 0.3 2.2 2 0 0 2 2 2 0 Transmembrane 52 RRM_1 PF00076.22 CDJ46738.1 - 4.5e-22 77.6 0.0 8.5e-08 31.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ46738.1 - 0.14 12.2 0.0 9.5 6.4 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif RT_RNaseH PF17917.1 CDJ46740.1 - 2.8e-12 46.9 0.3 5.8e-12 45.8 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ46740.1 - 2.1e-07 30.9 1.9 4.3e-07 29.9 1.9 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CDJ46740.1 - 0.00059 19.8 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ46740.1 - 0.001 18.7 0.2 0.022 14.3 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 CDJ46740.1 - 0.031 14.1 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like zf-HIT PF04438.16 CDJ46741.1 - 0.0012 18.7 17.9 0.002 18.0 17.9 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF4079 PF13301.6 CDJ46742.1 - 0.08 13.1 8.7 0.84 9.8 8.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DcuC PF03606.15 CDJ46742.1 - 0.096 11.1 1.1 0.17 10.3 1.1 1.4 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier HCO3_cotransp PF00955.21 CDJ46742.1 - 0.2 10.5 6.6 0.32 9.8 6.6 1.4 1 0 0 1 1 1 0 HCO3- transporter family 7TM_GPCR_Srx PF10328.9 CDJ46742.1 - 0.2 11.2 0.1 0.2 11.2 0.1 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx CitMHS_2 PF16980.5 CDJ46742.1 - 0.37 9.4 2.5 0.51 8.9 2.5 1.2 1 0 0 1 1 1 0 Putative citrate transport DUF2207 PF09972.9 CDJ46742.1 - 0.74 8.5 2.4 1.4 7.6 2.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4746 PF15928.5 CDJ46742.1 - 1.4 8.2 12.0 0.065 12.6 4.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) ArsP_2 PF11449.8 CDJ46742.1 - 2.4 7.3 8.4 4.7 6.3 8.4 1.6 1 1 0 1 1 1 0 Putative, 10TM heavy-metal exporter DUF4698 PF15769.5 CDJ46742.1 - 3 6.8 31.2 7.7 5.5 31.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4698) AF-4 PF05110.13 CDJ46742.1 - 4.3 5.3 63.3 0.49 8.4 19.3 2.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein BAF1_ABF1 PF04684.13 CDJ46742.1 - 6 5.8 33.2 2 7.3 17.1 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor PrmA PF06325.13 CDJ46743.1 - 7.8e-10 38.6 0.7 1.1e-09 38.1 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CDJ46743.1 - 2.9e-08 34.3 0.2 6.5e-08 33.2 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ46743.1 - 4.4e-07 29.6 0.1 1e-06 28.4 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CDJ46743.1 - 1.8e-06 27.8 0.0 2.7e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ46743.1 - 5.2e-06 27.0 0.1 2.4e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ46743.1 - 6.9e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CDJ46743.1 - 0.0012 18.8 0.1 0.002 18.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ46743.1 - 0.0016 19.2 0.0 0.0049 17.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ46743.1 - 0.003 16.9 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.15 CDJ46743.1 - 0.0046 16.6 0.1 0.0071 16.0 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CMAS PF02353.20 CDJ46743.1 - 0.0074 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 CDJ46743.1 - 0.011 15.8 1.1 0.012 15.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.11 CDJ46743.1 - 0.028 13.3 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.14 CDJ46743.1 - 0.04 13.3 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Csa1 PF06023.12 CDJ46743.1 - 0.044 13.1 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Apt1 PF10351.9 CDJ46743.1 - 0.055 12.3 0.7 0.056 12.3 0.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PCMT PF01135.19 CDJ46743.1 - 0.14 11.9 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Macoilin PF09726.9 CDJ46743.1 - 0.14 10.7 2.4 0.14 10.7 2.4 1.1 1 0 0 1 1 1 0 Macoilin family SDP_N PF12278.8 CDJ46743.1 - 0.39 10.8 6.6 0.58 10.3 6.6 1.2 1 0 0 1 1 1 0 Sex determination protein N terminal RskA PF10099.9 CDJ46744.1 - 0.11 12.8 2.6 0.11 12.8 2.6 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Androgen_recep PF02166.16 CDJ46744.1 - 1.3 7.8 7.8 1.5 7.5 7.8 1.1 1 0 0 1 1 1 0 Androgen receptor EOS1 PF12326.8 CDJ46745.1 - 0.035 14.1 3.4 0.04 13.8 3.4 1.0 1 0 0 1 1 1 0 N-glycosylation protein MetallophosC PF16370.5 CDJ46745.1 - 0.098 12.9 3.5 0.11 12.7 3.5 1.0 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase SpoIIP PF07454.11 CDJ46745.1 - 0.11 11.9 11.8 0.1 12.1 11.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FAM176 PF14851.6 CDJ46745.1 - 0.11 12.1 7.7 0.12 12.0 7.7 1.0 1 0 0 1 1 1 0 FAM176 family RNA_pol_Rpc4 PF05132.14 CDJ46745.1 - 0.13 12.7 8.3 0.13 12.7 8.3 1.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 RNA_pol_Rbc25 PF08292.12 CDJ46745.1 - 0.14 12.4 7.0 0.22 11.7 7.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Connexin PF00029.19 CDJ46745.1 - 0.24 11.1 10.0 0.24 11.1 10.0 1.0 1 0 0 1 1 1 0 Connexin DUF4770 PF15994.5 CDJ46745.1 - 0.26 11.5 9.9 0.26 11.5 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) AIF_C PF14721.6 CDJ46745.1 - 0.39 11.1 7.8 0.38 11.1 7.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EIIBC-GUT_N PF03612.14 CDJ46745.1 - 0.46 10.2 10.2 0.49 10.1 10.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 CDJ46745.1 - 0.47 9.2 12.2 0.44 9.2 12.2 1.0 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ46745.1 - 0.61 10.1 8.0 0.62 10.0 8.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Kei1 PF08552.11 CDJ46745.1 - 0.77 9.6 6.8 0.81 9.5 6.8 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Afi1 PF07792.12 CDJ46745.1 - 0.95 9.9 11.5 1 9.8 11.5 1.0 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CMS1 PF14617.6 CDJ46745.1 - 0.98 8.7 6.8 1 8.7 6.8 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF3537 PF12056.8 CDJ46745.1 - 1.1 8.0 3.5 1.1 8.0 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DUF913 PF06025.12 CDJ46745.1 - 1.1 8.1 7.3 1 8.2 7.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM91_C PF14648.6 CDJ46745.1 - 1.2 8.0 6.4 1.1 8.0 6.4 1.0 1 0 0 1 1 1 0 FAM91 C-terminus RNase_H2_suC PF08615.11 CDJ46745.1 - 1.2 9.3 11.1 1.3 9.2 11.1 1.0 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DDRGK PF09756.9 CDJ46745.1 - 1.2 8.6 20.5 1.5 8.4 20.5 1.0 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.12 CDJ46745.1 - 1.7 8.4 14.8 2 8.2 14.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 CDJ46745.1 - 1.7 7.7 7.6 1.9 7.6 7.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter RPA43_OB PF17875.1 CDJ46745.1 - 2 9.1 10.1 2.3 8.9 10.1 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DDHD PF02862.17 CDJ46745.1 - 2.2 8.4 11.6 2.2 8.4 11.6 1.0 1 0 0 1 1 1 0 DDHD domain DUF4820 PF16091.5 CDJ46745.1 - 2.3 7.5 12.3 2.3 7.5 12.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pox_P35 PF03213.14 CDJ46745.1 - 2.3 7.3 4.6 2.6 7.2 4.6 1.0 1 0 0 1 1 1 0 Poxvirus P35 protein Ctr PF04145.15 CDJ46745.1 - 2.4 8.7 5.1 2.6 8.6 5.1 1.0 1 0 0 1 1 1 0 Ctr copper transporter family Cellulose_synt PF03552.14 CDJ46745.1 - 2.5 6.5 5.9 2.5 6.5 5.9 1.0 1 0 0 1 1 1 0 Cellulose synthase Ureide_permease PF07168.11 CDJ46745.1 - 2.6 6.7 5.6 2.7 6.7 5.6 1.0 1 0 0 1 1 1 0 Ureide permease DUF4834 PF16118.5 CDJ46745.1 - 2.7 9.0 14.7 2.9 8.9 14.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Dicty_REP PF05086.12 CDJ46745.1 - 3.2 5.6 7.5 3 5.7 7.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RPN2_C PF18004.1 CDJ46745.1 - 3.4 7.6 16.1 3.6 7.5 16.1 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain GNAT_acetyltr_2 PF13718.6 CDJ46745.1 - 3.5 7.0 8.8 3.9 6.8 8.8 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Asparaginase_2 PF01112.18 CDJ46745.1 - 3.6 6.5 6.7 3.7 6.5 6.7 1.0 1 0 0 1 1 1 0 Asparaginase Sec62 PF03839.16 CDJ46745.1 - 3.7 7.0 10.7 4.3 6.8 10.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 TFB6 PF17110.5 CDJ46745.1 - 4.2 7.1 12.6 4.4 7.0 12.6 1.0 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Eapp_C PF10238.9 CDJ46745.1 - 4.4 7.4 14.9 5 7.2 14.9 1.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein PIP5K PF01504.18 CDJ46745.1 - 4.6 6.4 10.1 4.6 6.4 10.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF1980 PF09323.10 CDJ46745.1 - 4.8 7.1 8.8 4.6 7.1 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Tim54 PF11711.8 CDJ46745.1 - 4.9 5.8 14.5 4.9 5.8 14.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.13 CDJ46745.1 - 5.2 5.8 12.4 5.9 5.6 12.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3464 PF11947.8 CDJ46745.1 - 7 6.4 15.2 8.2 6.2 15.2 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Orf78 PF06024.12 CDJ46745.1 - 7.1 7.0 7.9 9.1 6.6 7.9 1.2 1 0 0 1 1 1 0 Orf78 (ac78) PPL5 PF18168.1 CDJ46745.1 - 7.5 5.7 10.7 7.7 5.7 10.7 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Pex14_N PF04695.13 CDJ46745.1 - 7.6 7.2 15.0 7.9 7.1 15.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.19 CDJ46745.1 - 8.1 4.2 14.9 9.1 4.1 14.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CobT PF06213.12 CDJ46745.1 - 8.2 5.7 21.5 9.2 5.6 21.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3043 PF11241.8 CDJ46745.1 - 8.6 6.4 11.9 9.8 6.2 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Baculo_PP31 PF05311.11 CDJ46745.1 - 8.8 5.7 13.8 9.4 5.6 13.8 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CPSF100_C PF13299.6 CDJ46745.1 - 8.8 6.5 14.2 9.2 6.4 14.2 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S49_N PF08496.10 CDJ46745.1 - 9.3 6.3 13.8 11 6.0 13.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.14 CDJ46745.1 - 9.7 4.3 13.7 10 4.3 13.7 1.0 1 0 0 1 1 1 0 CDC45-like protein FHIPEP PF00771.20 CDJ46745.1 - 9.8 4.5 9.3 9.6 4.5 9.3 1.0 1 0 0 1 1 1 0 FHIPEP family OKR_DC_1 PF01276.20 CDJ46746.1 - 3.7e-70 236.8 0.0 2.9e-53 181.1 0.0 2.3 2 0 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 CDJ46746.1 - 9e-05 21.9 0.0 0.00023 20.5 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase AAA_23 PF13476.6 CDJ46746.1 - 0.0001 22.9 23.1 0.016 15.8 12.8 2.5 2 0 0 2 2 2 2 AAA domain Ribosomal_60s PF00428.19 CDJ46746.1 - 0.00034 21.1 11.9 0.00095 19.7 11.9 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4407 PF14362.6 CDJ46746.1 - 0.0021 17.5 6.1 0.0021 17.5 6.1 2.4 2 0 0 2 2 1 1 Domain of unknown function (DUF4407) DUF3138 PF11336.8 CDJ46746.1 - 0.0037 15.9 9.9 0.0077 14.9 9.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) TFIIA PF03153.13 CDJ46746.1 - 0.0044 17.1 12.8 0.0044 17.1 12.8 2.7 2 1 0 2 2 1 1 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ46746.1 - 0.011 15.6 23.0 0.021 14.8 23.0 1.4 1 0 0 1 1 1 0 SPX domain OKR_DC_1_C PF03711.15 CDJ46746.1 - 0.059 13.7 0.4 0.059 13.7 0.4 4.0 3 1 2 5 5 5 0 Orn/Lys/Arg decarboxylase, C-terminal domain DUF45 PF01863.17 CDJ46746.1 - 5.4 7.0 22.0 0.37 10.8 13.5 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF45 FapA PF03961.13 CDJ46746.1 - 7.8 5.0 16.6 0.2 10.2 0.7 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF2722 PF10846.8 CDJ46747.1 - 0.0023 17.0 15.9 0.0023 17.0 15.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ46747.1 - 0.035 13.7 29.0 0.042 13.5 29.0 1.1 1 0 0 1 1 1 0 Spt20 family Eapp_C PF10238.9 CDJ46747.1 - 0.05 13.7 6.8 0.054 13.6 6.8 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein TFIIA PF03153.13 CDJ46747.1 - 0.13 12.2 26.4 0.16 11.9 26.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRR18 PF15671.5 CDJ46747.1 - 0.21 11.5 14.6 0.24 11.2 14.6 1.0 1 0 0 1 1 1 0 Proline-rich protein family 18 Med15 PF09606.10 CDJ46747.1 - 0.27 9.9 24.2 0.41 9.3 24.2 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal EPL1 PF10513.9 CDJ46747.1 - 0.35 11.3 9.4 0.42 11.0 9.4 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Mcm10 PF09332.11 CDJ46747.1 - 0.4 10.1 11.4 0.46 9.9 11.4 1.0 1 0 0 1 1 1 0 Mcm10 replication factor MMR1 PF08505.10 CDJ46747.1 - 0.53 10.5 10.7 0.58 10.4 10.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TERB2 PF15101.6 CDJ46747.1 - 0.68 10.0 14.2 0.84 9.7 14.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF702 PF05142.12 CDJ46747.1 - 0.76 10.2 11.1 0.98 9.9 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) NST1 PF13945.6 CDJ46747.1 - 1 9.4 14.2 1.1 9.3 14.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Roughex PF06020.11 CDJ46747.1 - 1 8.4 14.1 1.2 8.2 14.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein XRCC4 PF06632.12 CDJ46747.1 - 1.1 8.0 9.6 1.5 7.6 9.6 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Connexin PF00029.19 CDJ46747.1 - 1.3 8.8 4.4 1.3 8.7 4.4 1.1 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 CDJ46747.1 - 1.5 7.8 6.9 1.7 7.6 6.9 1.2 1 0 0 1 1 1 0 CLN3 protein Band_3_cyto PF07565.13 CDJ46747.1 - 1.8 8.3 7.4 1.8 8.3 7.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PIP5K PF01504.18 CDJ46747.1 - 1.9 7.7 5.2 2 7.6 5.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DivIC PF04977.15 CDJ46747.1 - 2 8.3 14.7 2.7 7.8 14.7 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF3295 PF11702.8 CDJ46747.1 - 2.2 7.6 14.6 2.5 7.3 14.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) ASFV_J13L PF05568.11 CDJ46747.1 - 2.2 8.0 18.7 2.6 7.8 18.7 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein TMEM51 PF15345.6 CDJ46747.1 - 2.3 8.0 16.2 3.1 7.6 16.2 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 Sec62 PF03839.16 CDJ46747.1 - 2.5 7.6 4.9 2.6 7.5 4.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3807 PF12720.7 CDJ46747.1 - 2.6 8.3 15.0 3.1 8.0 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SLC12 PF03522.15 CDJ46747.1 - 2.8 6.8 8.7 3 6.8 8.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 XRN_M PF17846.1 CDJ46747.1 - 3.1 6.7 10.1 3.3 6.5 10.1 1.0 1 0 0 1 1 1 0 Xrn1 helical domain RLL PF10036.9 CDJ46747.1 - 3.4 7.4 15.7 3.8 7.3 15.7 1.0 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Neur_chan_memb PF02932.16 CDJ46747.1 - 3.9 7.5 6.8 4.1 7.4 6.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0560 PF10577.9 CDJ46747.1 - 3.9 5.9 14.7 4.3 5.7 14.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 V_ATPase_I PF01496.19 CDJ46747.1 - 4.5 5.1 9.1 4.6 5.0 9.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 CDJ46747.1 - 4.5 5.7 12.6 5.3 5.5 12.6 1.1 1 0 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 CDJ46747.1 - 5 6.9 9.8 5.3 6.8 9.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ46747.1 - 5.6 5.6 14.0 5.8 5.6 14.0 1.1 1 0 0 1 1 1 0 Presenilin GramPos_pilinD1 PF16555.5 CDJ46747.1 - 5.6 7.1 9.6 7.3 6.7 9.6 1.3 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain Gti1_Pac2 PF09729.9 CDJ46747.1 - 5.6 7.0 8.6 6.2 6.9 8.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family UPF0565 PF10561.9 CDJ46747.1 - 5.8 6.0 7.7 6.6 5.8 7.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 GREB1 PF15782.5 CDJ46747.1 - 5.9 3.9 14.2 6.5 3.7 14.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4407 PF14362.6 CDJ46747.1 - 6.1 6.1 26.2 8 5.7 26.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Paf1 PF03985.13 CDJ46747.1 - 6.7 5.6 11.7 7.9 5.4 11.7 1.1 1 0 0 1 1 1 0 Paf1 Sin_N PF04801.13 CDJ46747.1 - 7 5.8 16.8 7.3 5.7 16.8 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DDHD PF02862.17 CDJ46747.1 - 7.9 6.6 10.7 9.7 6.3 10.7 1.2 1 0 0 1 1 1 0 DDHD domain Tic110 PF16940.5 CDJ46747.1 - 8.6 4.7 22.9 10 4.4 22.9 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter RskA PF10099.9 CDJ46748.1 - 0.067 13.5 51.7 0.038 14.3 21.0 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA FAM176 PF14851.6 CDJ46748.1 - 0.14 11.8 17.8 0.42 10.3 5.3 2.2 2 0 0 2 2 2 0 FAM176 family Spt20 PF12090.8 CDJ46748.1 - 0.35 10.4 66.8 0.57 9.8 27.1 2.1 2 0 0 2 2 2 0 Spt20 family SpoIIP PF07454.11 CDJ46748.1 - 0.77 9.2 31.3 0.4 10.1 9.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) IHABP4_N PF16174.5 CDJ46748.1 - 0.89 10.1 46.3 2.1 8.9 18.3 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal eIF-3_zeta PF05091.12 CDJ46748.1 - 0.94 8.4 43.2 0.36 9.8 17.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIF4E-T PF10477.9 CDJ46748.1 - 1.3 7.8 35.9 1.6 7.5 35.9 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Ctr PF04145.15 CDJ46748.1 - 1.5 9.5 22.8 0.25 12.0 4.8 2.2 2 0 0 2 2 2 0 Ctr copper transporter family Eapp_C PF10238.9 CDJ46748.1 - 1.5 8.9 31.1 1 9.4 11.9 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein CTNNB1_binding PF08347.11 CDJ46748.1 - 1.5 9.0 21.0 0.88 9.7 4.9 2.2 2 0 0 2 2 2 0 N-terminal CTNNB1 binding DUF3464 PF11947.8 CDJ46748.1 - 1.6 8.5 27.6 0.11 12.2 6.1 2.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Pinin_SDK_memA PF04696.13 CDJ46748.1 - 2.2 8.3 53.9 2.3 8.3 20.4 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF5523 PF17661.1 CDJ46748.1 - 3.4 7.3 26.6 2.2 7.9 8.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DUF3408 PF11888.8 CDJ46748.1 - 4.2 7.5 33.2 0.73 10.0 11.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF4834 PF16118.5 CDJ46748.1 - 4.4 8.3 35.0 4.3 8.4 12.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TERB2 PF15101.6 CDJ46748.1 - 6.4 6.8 41.5 2.1 8.3 14.9 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4569 PF15133.6 CDJ46748.1 - 7 6.3 35.2 1.7 8.3 15.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) Afi1 PF07792.12 CDJ46748.1 - 9.5 6.7 25.8 5.7 7.4 8.1 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DAG_kinase_N PF14513.6 CDJ46748.1 - 9.5 6.4 30.3 3.6 7.8 12.9 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus MMS19_N PF14500.6 CDJ46749.1 - 2.3e-29 102.8 0.2 2.3e-29 102.8 0.2 4.5 3 2 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II AF-4 PF05110.13 CDJ46749.1 - 0.00065 17.9 7.1 0.00065 17.9 7.1 13.7 7 4 3 11 11 11 2 AF-4 proto-oncoprotein BUD22 PF09073.10 CDJ46749.1 - 0.023 14.1 0.1 0.023 14.1 0.1 8.0 5 3 1 6 6 6 0 BUD22 Utp14 PF04615.13 CDJ46749.1 - 4.8 5.6 93.3 0.0027 16.4 30.6 5.6 4 2 0 4 4 4 0 Utp14 protein MutS_V PF00488.21 CDJ46750.1 - 5.3e-40 137.4 0.1 9.6e-40 136.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain V CCDC53 PF10152.9 CDJ46750.1 - 0.00074 20.0 0.8 0.00085 19.8 0.8 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex RskA PF10099.9 CDJ46750.1 - 0.0033 17.7 0.5 0.0051 17.1 0.5 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA FAM176 PF14851.6 CDJ46750.1 - 0.0045 16.7 0.2 0.0076 15.9 0.2 1.3 1 0 0 1 1 1 1 FAM176 family RCR PF12273.8 CDJ46750.1 - 0.0046 17.6 0.8 0.0059 17.3 0.8 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red CPSF100_C PF13299.6 CDJ46750.1 - 0.0056 16.9 0.4 0.0081 16.4 0.4 1.2 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CDJ46750.1 - 0.0078 15.0 1.8 0.0093 14.8 1.8 1.1 1 0 0 1 1 1 1 Presenilin DUF4471 PF14740.6 CDJ46750.1 - 0.0093 15.2 1.8 0.014 14.6 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF3408 PF11888.8 CDJ46750.1 - 0.012 15.8 4.2 0.025 14.7 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DDHD PF02862.17 CDJ46750.1 - 0.015 15.4 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.8 CDJ46750.1 - 0.018 13.9 3.3 0.023 13.5 3.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 CDJ46750.1 - 0.021 14.6 0.9 0.03 14.1 0.9 1.2 1 0 0 1 1 1 0 Connexin DUF4175 PF13779.6 CDJ46750.1 - 0.021 12.8 13.3 0.027 12.4 13.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SpoIIP PF07454.11 CDJ46750.1 - 0.024 14.1 4.4 0.033 13.7 4.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FAM101 PF15068.6 CDJ46750.1 - 0.027 14.5 0.6 0.038 14.0 0.6 1.2 1 0 0 1 1 1 0 FAM101 family eIF-3_zeta PF05091.12 CDJ46750.1 - 0.035 13.1 4.0 0.044 12.8 4.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Eapp_C PF10238.9 CDJ46750.1 - 0.037 14.1 5.2 0.054 13.6 5.2 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Spt20 PF12090.8 CDJ46750.1 - 0.043 13.4 22.0 0.062 12.9 22.0 1.1 1 0 0 1 1 1 0 Spt20 family EIIBC-GUT_N PF03612.14 CDJ46750.1 - 0.049 13.4 2.3 0.071 12.8 1.3 1.8 3 0 0 3 3 1 0 Sorbitol phosphotransferase enzyme II N-terminus OATP PF03137.20 CDJ46750.1 - 0.074 11.3 0.1 0.092 11.0 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CobT PF06213.12 CDJ46750.1 - 0.11 11.9 13.1 0.16 11.3 13.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Neur_chan_memb PF02932.16 CDJ46750.1 - 0.15 12.1 1.8 0.2 11.7 1.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_25 PF13481.6 CDJ46750.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain Ndc1_Nup PF09531.10 CDJ46750.1 - 0.18 10.4 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4770 PF15994.5 CDJ46750.1 - 0.19 12.0 7.7 0.25 11.5 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Folate_carrier PF01770.18 CDJ46750.1 - 0.23 10.2 0.1 0.38 9.5 0.1 1.4 1 0 0 1 1 1 0 Reduced folate carrier SKA1 PF07160.12 CDJ46750.1 - 0.31 10.9 8.8 0.46 10.3 8.8 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CLN3 PF02487.17 CDJ46750.1 - 0.32 10.0 1.8 0.46 9.5 1.8 1.3 1 0 0 1 1 1 0 CLN3 protein TFIIA PF03153.13 CDJ46750.1 - 0.72 9.8 20.7 0.91 9.4 20.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ46750.1 - 0.96 9.2 8.0 1.3 8.7 8.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pap_E4 PF02711.14 CDJ46750.1 - 1.1 10.3 9.2 1.8 9.6 9.2 1.3 1 0 0 1 1 1 0 E4 protein PAT1 PF09770.9 CDJ46750.1 - 1.2 7.3 13.4 1.6 6.9 13.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.6 CDJ46750.1 - 1.4 9.4 0.0 1.4 9.4 0.0 2.2 2 0 0 2 2 1 0 AAA domain eIF3_subunit PF08597.10 CDJ46750.1 - 1.8 8.4 10.8 3.8 7.4 9.7 1.8 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF4834 PF16118.5 CDJ46750.1 - 3.4 8.7 11.4 5.4 8.1 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 CDJ46750.1 - 3.7 6.3 21.6 8 5.2 21.6 1.5 1 0 0 1 1 1 0 Androgen receptor Suf PF05843.14 CDJ46750.1 - 4.8 7.1 9.2 6.4 6.7 9.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MAJIN PF15077.6 CDJ46750.1 - 5.1 6.8 7.3 7.4 6.3 7.3 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein ARF7EP_C PF14949.6 CDJ46750.1 - 5.4 7.7 12.5 14 6.3 12.5 1.6 1 1 0 1 1 1 0 ARF7 effector protein C-terminus V_ATPase_I PF01496.19 CDJ46750.1 - 6.5 4.5 9.5 8.9 4.1 9.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2828 PF11443.8 CDJ46750.1 - 7.2 4.6 7.2 9.9 4.1 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3464 PF11947.8 CDJ46750.1 - 7.2 6.3 9.2 12 5.7 9.2 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF3292 PF11696.8 CDJ46750.1 - 7.4 4.8 6.9 10 4.4 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Roughex PF06020.11 CDJ46750.1 - 8.4 5.4 12.2 13 4.7 12.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein MMR1 PF08505.10 CDJ46750.1 - 9.1 6.5 13.9 13 6.0 13.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF5320 PF17253.2 CDJ46752.1 - 0.0082 17.2 3.4 0.0082 17.2 3.4 4.3 2 1 2 4 4 4 1 Family of unknown function (DUF5320) DUF1140 PF06600.11 CDJ46752.1 - 0.11 12.9 1.5 0.3 11.6 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) Gpi16 PF04113.14 CDJ46753.1 - 2.5e-19 69.2 18.6 8e-17 60.9 14.7 2.4 2 0 0 2 2 2 2 Gpi16 subunit, GPI transamidase component Lin-8 PF03353.15 CDJ46753.1 - 0.0022 17.6 8.8 0.0022 17.6 8.8 5.2 4 2 0 4 4 4 1 Ras-mediated vulval-induction antagonist DUF3474 PF11960.8 CDJ46753.1 - 4.4 7.5 10.3 0.69 10.1 0.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3474) Peptidase_C2 PF00648.21 CDJ46754.1 - 1e-10 41.2 3.1 3.9e-09 36.0 2.7 4.2 3 1 1 4 4 4 2 Calpain family cysteine protease DUF2722 PF10846.8 CDJ46754.1 - 0.0025 16.9 2.9 0.0025 16.9 2.9 5.3 4 1 0 5 5 5 2 Protein of unknown function (DUF2722) DUF4667 PF15700.5 CDJ46754.1 - 0.0029 17.7 2.5 0.0029 17.7 2.5 5.4 4 2 1 5 5 5 2 Domain of unknown function (DUF4667) Dehydrin PF00257.19 CDJ46755.1 - 0.00047 20.7 8.3 0.00055 20.5 8.3 1.2 1 0 0 1 1 1 1 Dehydrin CPSF100_C PF13299.6 CDJ46755.1 - 0.0019 18.4 9.5 0.0024 18.1 9.5 1.1 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Shadoo PF14999.6 CDJ46755.1 - 0.0029 17.7 6.4 0.0038 17.3 6.4 1.2 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective SR-25 PF10500.9 CDJ46755.1 - 0.0065 16.1 15.4 0.0073 15.9 15.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF5521 PF17659.1 CDJ46755.1 - 0.011 13.6 7.3 0.012 13.5 7.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DUF3408 PF11888.8 CDJ46755.1 - 0.016 15.4 7.5 0.017 15.3 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) PMSI1 PF15322.6 CDJ46755.1 - 0.047 13.1 12.9 0.055 12.9 12.9 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative CDC45 PF02724.14 CDJ46755.1 - 0.054 11.8 10.7 0.053 11.8 10.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.18 CDJ46755.1 - 0.062 13.2 9.8 0.072 13.0 9.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF2052 PF09747.9 CDJ46755.1 - 0.069 13.3 12.9 0.075 13.1 12.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Paf1 PF03985.13 CDJ46755.1 - 0.097 11.7 18.8 0.11 11.5 18.8 1.0 1 0 0 1 1 1 0 Paf1 TLP-20 PF06088.11 CDJ46755.1 - 0.11 12.4 4.3 0.11 12.4 4.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) TFB6 PF17110.5 CDJ46755.1 - 0.24 11.1 2.9 0.28 10.9 2.9 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Cytomega_UL84 PF06284.11 CDJ46755.1 - 0.24 9.8 4.9 0.26 9.7 4.9 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein YbgS PF13985.6 CDJ46755.1 - 0.3 11.4 7.7 0.38 11.1 7.7 1.1 1 0 0 1 1 1 0 YbgS-like protein FHIPEP PF00771.20 CDJ46755.1 - 0.39 9.1 1.6 0.37 9.2 1.6 1.1 1 0 0 1 1 1 0 FHIPEP family Presenilin PF01080.17 CDJ46755.1 - 0.72 8.6 13.9 0.71 8.6 13.9 1.0 1 0 0 1 1 1 0 Presenilin NEMP PF10225.9 CDJ46755.1 - 0.72 9.5 2.9 0.73 9.5 2.9 1.2 1 0 0 1 1 1 0 NEMP family DUF4746 PF15928.5 CDJ46755.1 - 0.74 9.2 9.3 0.78 9.1 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SPATIAL PF15256.6 CDJ46755.1 - 0.77 10.1 7.6 0.82 10.0 7.6 1.1 1 0 0 1 1 1 0 SPATIAL TRAP_alpha PF03896.16 CDJ46755.1 - 0.79 8.9 5.6 0.85 8.8 5.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mem_trans PF03547.18 CDJ46755.1 - 0.89 7.9 3.6 0.93 7.8 3.6 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4820 PF16091.5 CDJ46755.1 - 0.97 8.8 7.8 1 8.7 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) R_equi_Vir PF05526.11 CDJ46755.1 - 1.1 9.1 3.8 1.3 8.8 3.8 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF3138 PF11336.8 CDJ46755.1 - 1.3 7.5 6.8 1.3 7.5 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FAM176 PF14851.6 CDJ46755.1 - 1.4 8.6 11.5 2 8.1 11.5 1.3 1 0 0 1 1 1 0 FAM176 family Apt1 PF10351.9 CDJ46755.1 - 1.4 7.7 12.2 1.6 7.5 12.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DDHD PF02862.17 CDJ46755.1 - 1.6 8.8 10.8 1.9 8.6 10.8 1.1 1 0 0 1 1 1 0 DDHD domain Sporozoite_P67 PF05642.11 CDJ46755.1 - 2.5 6.1 9.5 2.7 5.9 9.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SID-1_RNA_chan PF13965.6 CDJ46755.1 - 2.7 6.3 3.0 2.6 6.4 3.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PI3K_1B_p101 PF10486.9 CDJ46755.1 - 2.8 5.6 10.7 3.2 5.4 10.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SLC12 PF03522.15 CDJ46755.1 - 3.8 6.4 8.3 4.1 6.3 8.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 MMU163 PF17119.5 CDJ46755.1 - 4.4 6.4 7.3 5.2 6.2 7.3 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis SARAF PF06682.12 CDJ46755.1 - 4.5 6.8 12.8 5.4 6.6 12.8 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF913 PF06025.12 CDJ46755.1 - 4.7 6.1 8.5 4.7 6.1 8.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FancD2 PF14631.6 CDJ46755.1 - 4.9 4.4 7.6 5.2 4.3 7.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RR_TM4-6 PF06459.12 CDJ46755.1 - 5.9 6.6 15.3 6.5 6.5 15.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4228 PF14009.6 CDJ46755.1 - 6.6 7.1 14.1 8.5 6.7 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DNA_pol_phi PF04931.13 CDJ46755.1 - 7.6 4.5 16.0 8.8 4.3 16.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi Ferlin_C PF16165.5 CDJ46755.1 - 8.2 6.4 6.4 11 6.0 6.4 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Roughex PF06020.11 CDJ46755.1 - 8.4 5.4 12.8 9.4 5.2 12.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Aminotran_1_2 PF00155.21 CDJ46758.1 - 4.9e-41 141.1 0.0 5.7e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF5398 PF17376.2 CDJ46758.1 - 0.15 12.7 0.2 0.29 11.8 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5398) 7TM_GPCR_Sru PF10322.9 CDJ46759.1 - 0.46 9.8 1.0 0.5 9.6 0.0 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru TFIIA PF03153.13 CDJ46759.1 - 0.66 9.9 36.9 0.86 9.5 7.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ46759.1 - 0.68 10.2 13.7 0.96 9.7 6.3 2.6 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Ctr PF04145.15 CDJ46759.1 - 1.8 9.2 5.7 8.8 6.9 1.6 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Hom_end_hint PF05203.16 CDJ46759.1 - 4.6 7.1 10.0 0.097 12.6 3.0 1.7 2 0 0 2 2 2 0 Hom_end-associated Hint OATP PF03137.20 CDJ46759.1 - 7.2 4.8 8.2 1.5 7.1 1.1 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Slp PF03843.13 CDJ46759.1 - 8.9 5.7 11.1 0.53 9.6 3.5 2.2 2 0 0 2 2 2 0 Outer membrane lipoprotein Slp family Serinc PF03348.15 CDJ46760.1 - 1.8 7.4 6.9 0.51 9.2 2.8 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF4834 PF16118.5 CDJ46760.1 - 2.2 9.3 31.7 0.44 11.6 8.4 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) Spore_YhcN_YlaJ PF09580.10 CDJ46760.1 - 2.4 8.2 12.2 0.66 10.1 3.8 2.9 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) TRAP_alpha PF03896.16 CDJ46761.1 - 0.042 13.0 10.6 0.046 12.9 10.6 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1180 PF06679.12 CDJ46761.1 - 0.19 12.2 6.1 0.21 12.0 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CobT PF06213.12 CDJ46761.1 - 0.25 10.7 30.1 0.3 10.4 30.1 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT V_ATPase_I PF01496.19 CDJ46761.1 - 0.41 8.5 19.6 0.41 8.5 19.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2052 PF09747.9 CDJ46761.1 - 0.48 10.5 22.4 0.59 10.2 22.4 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2828 PF11443.8 CDJ46761.1 - 0.52 8.3 17.9 0.54 8.3 17.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3408 PF11888.8 CDJ46761.1 - 0.61 10.2 16.1 0.94 9.6 16.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) PSK PF06404.12 CDJ46761.1 - 0.65 11.0 15.1 0.81 10.7 15.1 1.2 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) DREPP PF05558.12 CDJ46761.1 - 0.94 9.3 8.8 1 9.2 8.8 1.0 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Connexin PF00029.19 CDJ46761.1 - 1.1 9.0 13.8 1.2 8.9 13.8 1.1 1 0 0 1 1 1 0 Connexin Baculo_PP31 PF05311.11 CDJ46761.1 - 1.1 8.6 13.8 1.3 8.4 13.8 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) PIP5K PF01504.18 CDJ46761.1 - 1.2 8.2 14.2 1.3 8.2 14.2 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SpoIIP PF07454.11 CDJ46761.1 - 1.9 7.8 19.7 2.3 7.6 19.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Velvet PF11754.8 CDJ46761.1 - 2 8.3 13.6 2.1 8.2 13.6 1.0 1 0 0 1 1 1 0 Velvet factor CLN3 PF02487.17 CDJ46761.1 - 2.8 6.9 14.2 3 6.8 14.2 1.0 1 0 0 1 1 1 0 CLN3 protein DUF913 PF06025.12 CDJ46761.1 - 2.9 6.8 12.0 3.1 6.7 12.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM176 PF14851.6 CDJ46761.1 - 3.3 7.4 16.8 6.7 6.4 16.8 1.5 1 1 0 1 1 1 0 FAM176 family Folate_carrier PF01770.18 CDJ46761.1 - 3.3 6.3 9.5 3.6 6.2 9.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier CCDC53 PF10152.9 CDJ46761.1 - 3.4 8.1 18.9 4 7.8 18.9 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CSG2 PF16965.5 CDJ46761.1 - 3.5 6.5 10.7 3.9 6.3 10.7 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator SID-1_RNA_chan PF13965.6 CDJ46761.1 - 3.5 5.9 8.5 3.8 5.8 8.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4446 PF14584.6 CDJ46761.1 - 4.9 7.1 10.9 5.2 7.0 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) SLC12 PF03522.15 CDJ46761.1 - 5.5 5.9 18.1 6.2 5.7 18.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ46761.1 - 5.9 6.9 15.1 6.3 6.8 15.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF5308 PF17233.2 CDJ46761.1 - 6.3 7.0 15.1 7.6 6.7 15.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Scs3p PF10261.9 CDJ46761.1 - 6.8 6.1 7.9 8 5.9 7.9 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Zip PF02535.22 CDJ46761.1 - 7.2 5.7 10.7 7.5 5.7 10.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter YABBY PF04690.13 CDJ46761.1 - 8.8 6.9 15.2 9.8 6.7 15.2 1.0 1 0 0 1 1 1 0 YABBY protein BORG_CEP PF14957.6 CDJ46761.1 - 9.5 7.4 13.0 11 7.3 13.0 1.1 1 0 0 1 1 1 0 Cdc42 effector TMCCDC2 PF15844.5 CDJ46762.1 - 0.045 13.7 3.1 0.095 12.6 3.1 1.4 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 Ndc1_Nup PF09531.10 CDJ46762.1 - 0.8 8.3 7.2 0.95 8.1 7.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 CDJ46762.1 - 2.1 6.8 28.5 3.3 6.1 28.5 1.2 1 0 0 1 1 1 0 Macoilin family DUF948 PF06103.11 CDJ46762.1 - 9.3 6.6 9.2 1.9 8.8 0.2 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Presenilin PF01080.17 CDJ46763.1 - 0.57 8.9 45.5 0.69 8.6 45.5 1.0 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 CDJ46763.1 - 3.2 7.3 34.8 3.7 7.1 34.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SLC12 PF03522.15 CDJ46763.1 - 4.5 6.2 39.8 5.4 5.9 39.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 CDJ46763.1 - 6 6.8 32.6 7.8 6.4 32.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A MIIP PF15734.5 CDJ46763.1 - 7.3 6.0 33.0 8.4 5.8 33.0 1.1 1 0 0 1 1 1 0 Migration and invasion-inhibitory SR-25 PF10500.9 CDJ46764.1 - 0.00019 21.1 24.8 0.00021 21.0 24.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 CDJ46764.1 - 0.51 11.2 18.5 0.67 10.8 18.5 1.2 1 0 0 1 1 1 0 Chorion family 2 CCSAP PF15748.5 CDJ46764.1 - 0.97 9.6 29.3 1.1 9.3 29.3 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated IMUP PF15761.5 CDJ46764.1 - 1 10.1 22.8 1.8 9.3 22.8 1.5 1 1 0 1 1 1 0 Immortalisation up-regulated protein G0-G1_switch_2 PF15103.6 CDJ46764.1 - 2.8 8.4 11.8 3.3 8.2 11.8 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF3292 PF11696.8 CDJ46764.1 - 3.6 5.9 14.0 3.6 5.8 14.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) TCP PF03634.13 CDJ46764.1 - 3.9 8.0 25.0 4.2 7.9 25.0 1.1 1 0 0 1 1 1 0 TCP family transcription factor Connexin PF00029.19 CDJ46764.1 - 9.1 6.0 13.6 9.1 6.0 13.6 1.2 1 0 0 1 1 1 0 Connexin SpoIIE PF07228.12 CDJ46765.1 - 3.3e-06 27.1 0.1 1.7e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) DUF3915 PF13054.6 CDJ46765.1 - 1.3 9.0 16.9 2.2 8.3 6.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) RskA PF10099.9 CDJ46766.1 - 0.00018 21.9 19.5 0.00023 21.5 19.5 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 CDJ46766.1 - 0.12 11.4 12.3 0.13 11.3 12.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SprA-related PF12118.8 CDJ46766.1 - 1 8.4 31.9 1.6 7.8 31.9 1.3 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.13 CDJ46766.1 - 1.8 8.5 29.0 2.2 8.2 29.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_DNAp_acc PF04929.12 CDJ46766.1 - 4.5 6.1 16.1 5.8 5.8 16.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor K_channel_TID PF07941.11 CDJ46766.1 - 5.5 7.5 36.5 1.6 9.2 31.2 2.5 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain CPSF100_C PF13299.6 CDJ46768.1 - 0.00037 20.7 4.7 0.00037 20.7 4.7 1.9 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal G-7-MTase PF12803.7 CDJ46768.1 - 0.014 14.6 0.2 0.02 14.1 0.2 1.3 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) CYLD_phos_site PF16607.5 CDJ46768.1 - 0.019 14.8 2.5 0.023 14.5 2.5 1.2 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured SARAF PF06682.12 CDJ46768.1 - 0.095 12.3 14.9 0.13 11.9 14.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PRC2_HTH_1 PF18118.1 CDJ46768.1 - 1.5 9.6 11.8 2 9.3 6.2 2.2 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain DUF3984 PF13136.6 CDJ46768.1 - 3.6 6.9 15.3 3.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) GWT1 PF06423.12 CDJ46768.1 - 5.8 7.0 9.3 17 5.5 9.3 1.8 1 1 0 1 1 1 0 GWT1 DUF4746 PF15928.5 CDJ46768.1 - 5.9 6.2 7.9 1.2 8.5 3.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RED_N PF07808.13 CDJ46768.1 - 6.3 6.3 26.2 0.18 11.4 15.7 2.0 2 0 0 2 2 2 0 RED-like protein N-terminal region Ureide_permease PF07168.11 CDJ46768.1 - 9.2 4.9 6.3 0.67 8.7 1.7 1.5 2 0 0 2 2 2 0 Ureide permease Spt20 PF12090.8 CDJ46769.1 - 0.0093 15.6 10.8 0.0093 15.6 10.8 2.3 2 0 0 2 2 2 2 Spt20 family BAF1_ABF1 PF04684.13 CDJ46769.1 - 0.051 12.6 7.3 0.067 12.2 7.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FliP PF00813.20 CDJ46769.1 - 3.6 7.4 7.1 1.8 8.4 4.8 1.7 1 1 0 1 1 1 0 FliP family BUD22 PF09073.10 CDJ46770.1 - 8.1e-05 22.1 13.9 8.1e-05 22.1 13.9 5.5 2 2 3 5 5 5 2 BUD22 Ribosomal_60s PF00428.19 CDJ46770.1 - 0.0006 20.4 20.2 0.0048 17.4 1.1 17.6 10 5 6 16 16 16 4 60s Acidic ribosomal protein DUF4179 PF13786.6 CDJ46770.1 - 0.018 15.5 26.2 0.89 10.1 1.1 8.0 7 0 0 7 7 7 0 Domain of unknown function (DUF4179) GETHR PF05671.11 CDJ46770.1 - 0.032 13.6 7.9 0.76 9.2 3.1 2.6 2 0 0 2 2 2 0 GETHR pentapeptide repeat (5 copies) DUF2207 PF09972.9 CDJ46770.1 - 0.3 9.8 0.0 0.3 9.8 0.0 3.9 2 1 1 4 4 4 0 Predicted membrane protein (DUF2207) DUF2722 PF10846.8 CDJ46771.1 - 0.01 14.8 28.4 0.091 11.7 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Connexin PF00029.19 CDJ46771.1 - 0.16 11.7 7.8 0.061 13.1 0.6 2.2 2 0 0 2 2 2 0 Connexin FAM76 PF16046.5 CDJ46771.1 - 2.3 7.5 14.2 4.4 6.6 8.1 2.2 2 0 0 2 2 2 0 FAM76 protein EOS1 PF12326.8 CDJ46771.1 - 3 7.8 4.2 3.1 7.7 0.1 2.4 2 0 0 2 2 2 0 N-glycosylation protein Band_3_cyto PF07565.13 CDJ46771.1 - 4.7 6.9 13.9 4.6 7.0 6.6 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PHD_2 PF13831.6 CDJ46772.1 - 1.4e-05 24.5 7.6 1.4e-05 24.5 7.6 1.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CDJ46772.1 - 2e-05 24.4 9.3 4.1e-05 23.4 9.3 1.5 1 0 0 1 1 1 1 PHD-finger RskA PF10099.9 CDJ46772.1 - 0.0015 18.9 11.2 0.0015 18.9 11.2 12.1 3 3 5 8 8 8 2 Anti-sigma-K factor rskA DUF1645 PF07816.11 CDJ46772.1 - 0.0038 17.9 4.5 0.0038 17.9 4.5 7.6 7 1 0 7 7 7 1 Protein of unknown function (DUF1645) Prok-RING_1 PF14446.6 CDJ46772.1 - 0.011 15.6 2.4 0.025 14.5 2.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Presenilin PF01080.17 CDJ46773.1 - 0.00012 20.9 29.8 0.00016 20.6 29.8 1.3 1 0 0 1 1 1 1 Presenilin Hid1 PF12722.7 CDJ46773.1 - 0.00021 19.6 0.1 0.00021 19.6 0.1 2.8 1 1 2 3 3 2 1 High-temperature-induced dauer-formation protein V_ATPase_I PF01496.19 CDJ46773.1 - 0.068 11.1 33.9 0.089 10.7 33.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Caldesmon PF02029.15 CDJ46773.1 - 0.1 11.4 37.5 0.11 11.2 37.5 1.1 1 0 0 1 1 1 0 Caldesmon DUF966 PF06136.13 CDJ46773.1 - 0.26 11.0 27.6 0.32 10.7 27.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Dicty_REP PF05086.12 CDJ46773.1 - 0.38 8.7 19.5 0.47 8.4 19.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SLC12 PF03522.15 CDJ46773.1 - 0.46 9.4 36.5 0.58 9.1 36.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF572 PF04502.13 CDJ46773.1 - 0.63 9.6 29.9 0.83 9.2 29.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CCSAP PF15748.5 CDJ46773.1 - 0.67 10.1 40.1 0.91 9.6 40.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated GREB1 PF15782.5 CDJ46773.1 - 0.72 6.9 31.7 0.84 6.7 31.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 CDJ46773.1 - 1.4 7.9 33.1 1.8 7.6 33.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SARG PF15385.6 CDJ46773.1 - 1.7 7.8 35.9 2 7.5 35.9 1.0 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Exonuc_VII_L PF02601.15 CDJ46773.1 - 2.1 7.8 32.2 2.9 7.4 32.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CDK5_activator PF03261.15 CDJ46773.1 - 2.1 7.8 24.4 2.5 7.5 24.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PPP4R2 PF09184.11 CDJ46773.1 - 2.1 7.8 25.0 3.5 7.1 25.0 1.3 1 0 0 1 1 1 0 PPP4R2 DUF4045 PF13254.6 CDJ46773.1 - 2.4 7.7 33.9 3.4 7.2 33.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PNISR PF15996.5 CDJ46773.1 - 2.6 8.3 45.7 4 7.7 45.7 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Draxin PF15550.6 CDJ46773.1 - 3.1 7.6 25.0 3.9 7.2 25.0 1.1 1 0 0 1 1 1 0 Draxin Dapper PF15268.6 CDJ46773.1 - 4.9 5.9 40.1 6.1 5.6 40.1 1.0 1 0 0 1 1 1 0 Dapper SAPS PF04499.15 CDJ46773.1 - 5.6 5.6 30.1 7.5 5.2 30.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 CDJ46773.1 - 6 5.0 36.9 7.5 4.6 36.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDJ46773.1 - 7.9 4.6 37.4 10 4.3 37.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RskA PF10099.9 CDJ46774.1 - 0.0025 18.1 11.8 0.0026 18.1 11.8 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF755 PF05501.11 CDJ46774.1 - 0.034 14.4 21.1 0.034 14.4 21.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Ribosomal_60s PF00428.19 CDJ46774.1 - 0.05 14.2 13.5 0.08 13.5 13.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein BAF1_ABF1 PF04684.13 CDJ46774.1 - 0.34 9.9 21.5 0.37 9.8 21.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Adeno_PV PF03910.13 CDJ46774.1 - 0.49 9.0 12.0 0.48 9.1 12.0 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV PMSI1 PF15322.6 CDJ46774.1 - 0.85 9.0 13.7 1.2 8.5 13.7 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Paf1 PF03985.13 CDJ46774.1 - 1.1 8.2 11.8 1.2 8.0 11.8 1.1 1 0 0 1 1 1 0 Paf1 SID-1_RNA_chan PF13965.6 CDJ46774.1 - 1.8 6.9 3.7 1.9 6.8 3.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 IHABP4_N PF16174.5 CDJ46774.1 - 1.8 9.1 11.7 2.4 8.7 11.7 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal API5 PF05918.11 CDJ46774.1 - 2.1 7.1 10.9 2.2 7.0 10.9 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF1387 PF07139.11 CDJ46774.1 - 2.3 7.9 17.7 2.6 7.7 17.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Ctr PF04145.15 CDJ46774.1 - 4.1 8.0 7.3 5.2 7.7 7.0 1.3 1 1 0 1 1 1 0 Ctr copper transporter family SUIM_assoc PF16619.5 CDJ46774.1 - 5 7.3 18.9 9.4 6.4 18.7 2.0 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Menin PF05053.13 CDJ46774.1 - 5.7 5.2 16.9 7.7 4.7 16.9 1.2 1 0 0 1 1 1 0 Menin TFIIA PF03153.13 CDJ46774.1 - 6.9 6.6 20.4 7.2 6.5 20.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MlrC_C PF07171.12 CDJ46775.1 - 0.011 15.9 2.8 0.011 15.9 2.8 1.8 2 0 0 2 2 2 0 MlrC C-terminus DAD PF02109.16 CDJ46775.1 - 0.91 9.9 0.1 0.91 9.9 0.1 2.3 2 1 0 2 2 2 0 DAD family CD20 PF04103.15 CDJ46775.1 - 1.1 9.3 2.5 11 6.1 0.0 2.2 2 0 0 2 2 2 0 CD20-like family LMBR1 PF04791.16 CDJ46775.1 - 3.2 6.6 15.1 3.2 6.5 15.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UCH PF00443.29 CDJ46776.1 - 1.6e-06 27.8 0.0 1.6e-06 27.8 0.0 5.1 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUF2722 PF10846.8 CDJ46776.1 - 0.0063 15.5 1.3 0.0063 15.5 1.3 10.4 4 1 6 10 10 10 1 Protein of unknown function (DUF2722) LMBR1 PF04791.16 CDJ46776.1 - 0.038 12.9 0.1 0.038 12.9 0.1 3.9 2 1 0 2 2 2 0 LMBR1-like membrane protein Ribosomal_60s PF00428.19 CDJ46777.1 - 0.013 16.1 14.0 0.015 15.9 14.0 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ46777.1 - 0.031 14.6 6.0 0.032 14.5 6.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA PepSY_2 PF13670.6 CDJ46777.1 - 0.93 9.5 8.1 1.2 9.2 8.1 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF3824 PF12868.7 CDJ46777.1 - 4.8 7.8 14.6 1.2 9.8 11.2 1.7 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Pkinase PF00069.25 CDJ46778.1 - 1.7e-09 37.5 0.0 1.7e-09 37.5 0.0 2.7 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ46778.1 - 0.00021 20.7 0.0 0.0015 17.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase DUF572 PF04502.13 CDJ46778.1 - 0.0079 15.9 2.7 0.0079 15.9 2.7 4.5 3 2 0 4 4 4 1 Family of unknown function (DUF572) SID-1_RNA_chan PF13965.6 CDJ46778.1 - 0.39 9.1 0.9 0.82 8.0 0.9 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spt20 PF12090.8 CDJ46778.1 - 2.2 7.9 99.5 0.7 9.5 10.1 6.3 6 0 0 6 6 6 0 Spt20 family INO80_Ies4 PF08193.11 CDJ46779.1 - 0.012 15.7 2.6 0.012 15.7 2.6 3.8 3 1 1 4 4 4 0 INO80 complex subunit Ies4 TERB2 PF15101.6 CDJ46779.1 - 0.094 12.8 2.1 0.18 11.9 2.1 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ46779.1 - 0.37 10.4 11.2 0.13 11.8 8.6 1.6 2 0 0 2 2 2 0 Spt20 family AIG1 PF04548.16 CDJ46779.1 - 0.77 9.0 3.5 23 4.2 0.0 2.2 2 0 0 2 2 2 0 AIG1 family Phostensin_N PF13916.6 CDJ46779.1 - 4.5 7.7 13.4 6.1 7.3 10.9 2.6 2 1 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Mt_ATP-synt_D PF05873.12 CDJ46780.1 - 0.0021 17.9 0.2 0.0021 17.9 0.2 2.8 3 0 0 3 3 3 1 ATP synthase D chain, mitochondrial (ATP5H) EFTUD2 PF16004.5 CDJ46780.1 - 0.64 10.6 6.8 10 6.8 2.2 2.3 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus TRAUB PF08164.12 CDJ46781.1 - 7e-12 45.7 0.0 7e-12 45.7 0.0 3.5 4 1 0 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 CDJ46781.1 - 0.0021 18.7 13.7 0.0021 18.7 13.7 2.9 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor DUF2433 PF10360.9 CDJ46781.1 - 3.9 7.6 6.3 0.77 9.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2433) LLC1 PF14945.6 CDJ46782.1 - 1.6 9.3 8.8 7.3 7.2 0.8 2.7 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein RNA_POL_M_15KD PF02150.16 CDJ46785.1 - 6.5e-08 32.3 4.2 6.5e-08 32.3 4.2 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CDJ46785.1 - 1.5e-07 31.2 0.4 1.5e-07 31.2 0.4 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Nudc_N PF14050.6 CDJ46785.1 - 0.012 15.6 0.9 0.023 14.7 0.2 1.8 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. zf-ribbon_3 PF13248.6 CDJ46785.1 - 0.079 12.4 6.6 3.3 7.3 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 CDJ46785.1 - 0.11 12.2 2.1 7.8 6.3 0.2 2.9 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Pox_A8 PF04745.12 CDJ46785.1 - 0.22 10.5 0.1 0.32 10.0 0.1 1.1 1 0 0 1 1 1 0 VITF-3 subunit protein CpXC PF14353.6 CDJ46785.1 - 0.36 10.9 0.1 0.36 10.9 0.1 2.8 2 2 2 4 4 4 0 CpXC protein PHD PF00628.29 CDJ46785.1 - 0.45 10.5 7.2 5.5 7.0 2.5 3.2 3 1 0 3 3 3 0 PHD-finger zf-4CXXC_R1 PF10497.9 CDJ46785.1 - 1.4 9.2 6.7 1.9 8.8 0.1 2.6 2 1 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Zn_ribbon_recom PF13408.6 CDJ46785.1 - 1.4 9.5 5.0 0.49 10.9 0.3 2.4 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain zf-UBP PF02148.19 CDJ46785.1 - 2.4 8.6 7.0 56 4.2 0.0 3.3 2 1 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein zf-IS66 PF13005.7 CDJ46785.1 - 3.2 8.2 8.9 1.8 9.1 1.0 3.0 3 1 0 3 3 3 0 zinc-finger binding domain of transposase IS66 DZR PF12773.7 CDJ46785.1 - 5.5 7.1 10.6 20 5.3 7.4 2.7 1 1 1 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 CDJ46785.1 - 9.8 6.2 8.0 20 5.3 0.9 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PAP2_C PF14360.6 CDJ46786.1 - 3.6e-08 33.8 14.0 4.3e-07 30.4 4.2 2.8 2 0 0 2 2 2 2 PAP2 superfamily C-terminal PAP2 PF01569.21 CDJ46786.1 - 1.5 8.5 9.9 7.8 6.3 6.2 3.0 2 1 0 2 2 2 0 PAP2 superfamily Serinc PF03348.15 CDJ46787.1 - 0.00039 19.5 0.1 0.00041 19.4 0.1 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) TFIIA PF03153.13 CDJ46787.1 - 0.00053 20.1 17.5 0.00053 20.1 17.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4746 PF15928.5 CDJ46787.1 - 0.00061 19.3 8.4 0.00082 18.9 8.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) SAGA-Tad1 PF12767.7 CDJ46787.1 - 0.0017 18.1 2.6 0.0023 17.7 2.6 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Suf PF05843.14 CDJ46787.1 - 0.0073 16.3 6.2 0.0074 16.3 6.2 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) MecA PF05389.12 CDJ46787.1 - 0.019 14.6 1.3 0.022 14.4 1.3 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF719 PF05334.13 CDJ46787.1 - 0.023 14.9 5.4 0.035 14.3 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Spt20 PF12090.8 CDJ46787.1 - 0.023 14.3 28.3 0.03 13.9 28.3 1.1 1 0 0 1 1 1 0 Spt20 family FAM176 PF14851.6 CDJ46787.1 - 0.023 14.3 2.6 0.043 13.5 2.6 1.4 1 0 0 1 1 1 0 FAM176 family DUF2126 PF09899.9 CDJ46787.1 - 0.042 11.9 3.9 0.057 11.5 3.9 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Connexin PF00029.19 CDJ46787.1 - 0.063 13.0 0.6 0.072 12.8 0.6 1.2 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 CDJ46787.1 - 0.068 13.2 1.0 0.075 13.1 1.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNA_pol_Rbc25 PF08292.12 CDJ46787.1 - 0.22 11.8 4.3 0.3 11.3 4.3 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 SID-1_RNA_chan PF13965.6 CDJ46787.1 - 0.26 9.7 0.1 0.31 9.4 0.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DNApol_Exo PF18136.1 CDJ46787.1 - 0.33 10.1 8.0 0.51 9.4 8.0 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain eIF-3_zeta PF05091.12 CDJ46787.1 - 0.35 9.8 9.9 0.42 9.5 9.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ46787.1 - 0.35 10.9 11.5 0.47 10.5 11.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Conotoxin PF02950.17 CDJ46787.1 - 0.37 11.8 4.5 37 5.4 6.0 2.4 2 0 0 2 2 2 0 Conotoxin Borrelia_P83 PF05262.11 CDJ46787.1 - 0.43 9.0 8.6 0.59 8.6 8.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein OAD_gamma PF04277.13 CDJ46787.1 - 0.44 11.2 8.5 11 6.7 0.0 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain CobT PF06213.12 CDJ46787.1 - 0.45 9.9 12.9 0.62 9.4 12.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF775 PF05603.12 CDJ46787.1 - 0.48 9.9 8.1 0.64 9.5 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Band_3_cyto PF07565.13 CDJ46787.1 - 0.5 10.1 4.8 0.63 9.8 4.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RR_TM4-6 PF06459.12 CDJ46787.1 - 0.57 10.0 7.3 0.71 9.6 7.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.13 CDJ46787.1 - 0.63 10.7 16.2 1.1 9.9 16.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.19 CDJ46787.1 - 0.74 7.7 5.9 0.88 7.4 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EIIBC-GUT_N PF03612.14 CDJ46787.1 - 0.97 9.1 7.8 1.4 8.7 7.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SpoIIP PF07454.11 CDJ46787.1 - 1.1 8.6 10.1 1.5 8.2 10.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Ndc1_Nup PF09531.10 CDJ46787.1 - 1.7 7.3 5.4 1.8 7.1 5.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFB6 PF17110.5 CDJ46787.1 - 1.7 8.4 5.6 2.6 7.8 5.6 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Orf78 PF06024.12 CDJ46787.1 - 1.8 8.9 4.3 15 6.0 5.9 1.6 2 0 0 2 2 1 0 Orf78 (ac78) PBP_sp32 PF07222.12 CDJ46787.1 - 1.9 7.9 10.0 2.4 7.5 10.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 UPF0560 PF10577.9 CDJ46787.1 - 1.9 6.9 15.5 2.3 6.6 15.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PAT1 PF09770.9 CDJ46787.1 - 2.5 6.2 18.1 3 6.0 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AIF_C PF14721.6 CDJ46787.1 - 4.8 7.5 7.3 8 6.8 7.3 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Peptidase_S49_N PF08496.10 CDJ46787.1 - 5.1 7.1 9.3 1.4 9.0 6.3 1.5 2 0 0 2 2 1 0 Peptidase family S49 N-terminal CLN3 PF02487.17 CDJ46787.1 - 5.4 5.9 5.3 8.3 5.3 5.3 1.2 1 0 0 1 1 1 0 CLN3 protein DUF3464 PF11947.8 CDJ46787.1 - 5.7 6.7 11.9 8.9 6.1 11.9 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF3408 PF11888.8 CDJ46787.1 - 5.8 7.1 11.5 8.3 6.6 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Kei1 PF08552.11 CDJ46787.1 - 8.6 6.2 7.7 7.4 6.4 6.2 1.6 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 RR_TM4-6 PF06459.12 CDJ46790.1 - 0.27 11.0 23.5 0.29 10.9 23.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Endostatin PF06482.11 CDJ46790.1 - 0.95 8.9 20.2 0.94 8.9 20.2 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin VIR_N PF15912.5 CDJ46790.1 - 1.4 8.5 11.4 1.4 8.5 11.4 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Neur_chan_memb PF02932.16 CDJ46790.1 - 1.4 8.9 16.7 1.4 8.9 16.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF908 PF06012.12 CDJ46790.1 - 1.5 8.2 19.4 1.5 8.1 19.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF726 PF05277.12 CDJ46790.1 - 1.5 7.7 4.0 1.8 7.4 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Velvet PF11754.8 CDJ46790.1 - 1.6 8.7 19.7 1.8 8.4 19.7 1.3 1 0 0 1 1 1 0 Velvet factor Exonuc_VII_L PF02601.15 CDJ46790.1 - 1.9 8.0 27.6 2.1 7.9 27.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SID-1_RNA_chan PF13965.6 CDJ46790.1 - 2.2 6.6 10.0 2.1 6.7 10.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PIP5K PF01504.18 CDJ46790.1 - 2.5 7.2 14.9 2.9 7.0 14.9 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase TCP PF03634.13 CDJ46790.1 - 3.4 8.2 26.3 3.9 8.0 26.3 1.2 1 0 0 1 1 1 0 TCP family transcription factor eIF-3_zeta PF05091.12 CDJ46790.1 - 3.6 6.5 30.7 4 6.3 30.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.17 CDJ46790.1 - 4.3 7.4 21.1 5.1 7.2 21.1 1.3 1 0 0 1 1 1 0 DDHD domain Peptidase_S15 PF02129.18 CDJ46790.1 - 5.2 6.6 20.0 7.9 6.0 20.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Presenilin PF01080.17 CDJ46790.1 - 5.8 5.6 30.1 6.2 5.5 30.1 1.1 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 CDJ46790.1 - 6.6 5.5 13.1 7.8 5.3 13.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ureide_permease PF07168.11 CDJ46790.1 - 7.3 5.2 11.1 10 4.8 11.1 1.3 1 0 0 1 1 1 0 Ureide permease FAM60A PF15396.6 CDJ46790.1 - 8.1 6.4 19.6 9.6 6.1 19.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF913 PF06025.12 CDJ46790.1 - 8.3 5.3 15.7 8.3 5.3 15.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PAT1 PF09770.9 CDJ46790.1 - 8.4 4.5 42.8 8.8 4.5 42.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cellulose_synt PF03552.14 CDJ46790.1 - 10 4.5 10.7 11 4.4 10.7 1.0 1 0 0 1 1 1 0 Cellulose synthase Frizzled PF01534.17 CDJ46791.1 - 0.54 9.2 7.3 0.29 10.1 5.6 1.4 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region Collagen PF01391.18 CDJ46794.1 - 0.00013 21.6 75.8 0.00028 20.6 25.7 4.3 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Tim54 PF11711.8 CDJ46794.1 - 0.013 14.4 5.5 0.018 13.8 5.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.13 CDJ46794.1 - 0.17 11.8 10.8 0.26 11.2 10.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ46794.1 - 0.64 9.4 3.4 0.88 9.0 3.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2722 PF10846.8 CDJ46794.1 - 0.77 8.6 11.1 1 8.2 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ46794.1 - 1 8.1 4.3 1.5 7.5 4.3 1.1 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 CDJ46794.1 - 2.2 7.9 5.4 3.6 7.2 5.4 1.2 1 0 0 1 1 1 0 FAM176 family DUF4770 PF15994.5 CDJ46794.1 - 4.4 7.5 7.2 6.9 6.9 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Spt20 PF12090.8 CDJ46794.1 - 4.9 6.7 19.1 7.4 6.1 19.1 1.1 1 0 0 1 1 1 0 Spt20 family NAD_binding_11 PF14833.6 CDJ46796.1 - 4.3e-32 110.9 0.1 1e-31 109.7 0.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 CDJ46796.1 - 2.8e-28 99.1 0.4 4.2e-18 66.0 0.0 2.3 1 1 1 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CDJ46796.1 - 4.6e-08 33.5 0.1 9.3e-08 32.6 0.1 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CDJ46796.1 - 1.8e-05 24.2 0.0 3.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CDJ46796.1 - 0.00032 20.8 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CDJ46796.1 - 0.00095 19.1 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 CDJ46796.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 CDJ46796.1 - 0.13 11.9 0.2 5.3 6.6 0.0 2.2 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ran_BP1 PF00638.18 CDJ46797.1 - 3.6e-37 127.3 2.0 8.9e-37 126.1 2.0 1.6 1 0 0 1 1 1 1 RanBP1 domain Coilin_N PF15862.5 CDJ46797.1 - 0.01 15.6 9.5 0.02 14.7 9.5 1.5 1 0 0 1 1 1 0 Coilin N-terminus CDC45 PF02724.14 CDJ46797.1 - 0.015 13.6 11.2 0.019 13.3 11.2 1.2 1 0 0 1 1 1 0 CDC45-like protein WH1 PF00568.23 CDJ46797.1 - 0.028 14.4 1.1 0.091 12.7 1.1 1.8 1 1 0 1 1 1 0 WH1 domain DUF913 PF06025.12 CDJ46797.1 - 0.17 10.8 5.5 0.21 10.5 5.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CDJ46797.1 - 7.4 5.2 11.7 11 4.7 11.7 1.3 1 0 0 1 1 1 0 Presenilin CytochromB561_N PF09786.9 CDJ46798.1 - 0.36 9.8 4.8 0.49 9.3 4.8 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal RR_TM4-6 PF06459.12 CDJ46798.1 - 0.58 9.9 16.6 1 9.1 16.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SR-25 PF10500.9 CDJ46799.1 - 0.00041 20.0 33.4 0.00041 20.0 33.4 14.9 9 5 4 13 13 13 4 Nuclear RNA-splicing-associated protein Brix PF04427.18 CDJ46800.1 - 4.8e-08 33.3 0.0 5.3e-06 26.7 0.0 2.5 1 1 1 2 2 2 2 Brix domain RskA PF10099.9 CDJ46800.1 - 0.0019 18.5 14.7 0.0019 18.5 14.7 4.2 1 1 3 4 4 4 1 Anti-sigma-K factor rskA ATHILA PF03078.15 CDJ46800.1 - 0.44 9.3 6.5 0.62 8.8 6.5 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family DUF2232 PF09991.9 CDJ46801.1 - 0.054 12.7 0.7 0.079 12.1 0.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) RAP1 PF07218.11 CDJ46801.1 - 0.22 9.8 2.7 0.26 9.5 2.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ46801.1 - 1.6 8.3 23.1 4.1 7.0 23.2 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein APH PF01636.23 CDJ46801.1 - 2.5 8.0 7.3 0.051 13.5 0.8 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Sec23_trunk PF04811.15 CDJ46802.1 - 9.4e-22 77.8 0.0 3.7e-21 75.8 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CDJ46802.1 - 3.9e-16 58.7 0.5 3.9e-16 58.7 0.5 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CDJ46802.1 - 7.2e-10 38.8 4.0 1.5e-09 37.8 4.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CDJ46802.1 - 1.5e-08 35.2 0.0 1.7e-07 31.8 0.0 2.6 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Peptidase_M18 PF02127.15 CDJ46803.1 - 1.7e-50 172.1 0.2 1.5e-32 113.0 0.0 2.0 1 1 1 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CDJ46803.1 - 2.9e-07 29.8 0.0 2.5e-06 26.7 0.0 1.9 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Urease_alpha PF00449.20 CDJ46803.1 - 0.0055 17.0 0.1 0.012 15.9 0.0 1.5 1 1 1 2 2 2 1 Urease alpha-subunit, N-terminal domain SR-25 PF10500.9 CDJ46804.1 - 0.023 14.3 25.7 0.029 14.0 25.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ46804.1 - 0.067 13.2 33.0 0.096 12.7 33.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ46804.1 - 0.15 11.6 20.0 0.17 11.4 20.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MAP65_ASE1 PF03999.12 CDJ46804.1 - 0.19 10.4 23.4 0.2 10.3 23.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF2052 PF09747.9 CDJ46804.1 - 1.1 9.3 12.7 1.3 9.1 12.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AF-4 PF05110.13 CDJ46804.1 - 1.3 7.0 26.0 1.6 6.8 26.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sin_N PF04801.13 CDJ46804.1 - 1.3 8.1 19.6 1.5 7.9 19.6 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Miga PF10265.9 CDJ46804.1 - 1.4 7.8 18.5 1.5 7.7 18.5 1.1 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 CDJ46804.1 - 1.7 7.4 19.3 1.9 7.3 19.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ46804.1 - 1.7 8.5 21.4 1.8 8.4 21.4 1.1 1 0 0 1 1 1 0 SPX domain FAM220 PF15487.6 CDJ46804.1 - 4.1 7.0 15.1 4.2 6.9 15.1 1.2 1 0 0 1 1 1 0 FAM220 family HSD3 PF15244.6 CDJ46804.1 - 5.3 6.4 18.3 5.9 6.3 18.3 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 GREB1 PF15782.5 CDJ46804.1 - 6 3.8 24.2 6.6 3.7 24.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1387 PF07139.11 CDJ46804.1 - 6.3 6.4 19.7 7.9 6.1 19.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CCSAP PF15748.5 CDJ46804.1 - 6.9 6.8 26.9 8.8 6.4 26.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SLC12 PF03522.15 CDJ46804.1 - 8.9 5.2 16.8 9.1 5.2 16.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 CDJ46804.1 - 9.2 4.6 19.2 9.3 4.6 19.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 K_channel_TID PF07941.11 CDJ46805.1 - 0.048 14.1 1.2 0.048 14.1 1.2 4.5 2 1 2 4 4 3 0 Potassium channel Kv1.4 tandem inactivation domain Presenilin PF01080.17 CDJ46805.1 - 0.05 12.4 12.6 0.048 12.4 12.6 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ46805.1 - 0.09 12.8 8.3 0.093 12.7 8.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hydin_ADK PF17213.3 CDJ46805.1 - 0.16 12.2 14.5 0.19 12.0 14.5 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Macoilin PF09726.9 CDJ46805.1 - 0.23 10.0 14.4 0.24 9.9 14.4 1.1 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 CDJ46805.1 - 0.41 9.4 10.1 0.36 9.6 10.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 CDJ46805.1 - 0.5 9.2 11.7 0.45 9.3 11.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Band_3_cyto PF07565.13 CDJ46805.1 - 1 9.1 10.7 1.2 8.9 10.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TFIIA PF03153.13 CDJ46805.1 - 1.2 9.0 25.7 1.3 8.9 25.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ46805.1 - 1.3 9.1 9.6 1.4 8.9 9.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Velvet PF11754.8 CDJ46805.1 - 1.3 8.9 11.6 1.4 8.8 11.6 1.2 1 0 0 1 1 1 0 Velvet factor DAG_kinase_N PF14513.6 CDJ46805.1 - 1.4 9.1 11.7 2.1 8.5 11.7 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus SOBP PF15279.6 CDJ46805.1 - 1.5 9.4 11.9 1.6 9.3 11.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4569 PF15133.6 CDJ46805.1 - 1.9 8.1 15.0 2.1 8.0 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Connexin PF00029.19 CDJ46805.1 - 2 8.1 4.6 2.5 7.8 4.6 1.2 1 0 0 1 1 1 0 Connexin Tim54 PF11711.8 CDJ46805.1 - 2.4 6.8 9.0 2.9 6.6 9.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4551 PF15087.6 CDJ46805.1 - 2.7 6.7 13.1 2.6 6.8 13.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3807 PF12720.7 CDJ46805.1 - 3 8.1 17.7 4.1 7.6 17.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2126 PF09899.9 CDJ46805.1 - 4 5.4 7.2 4.3 5.3 7.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Membralin PF09746.9 CDJ46805.1 - 4 6.4 6.3 4.2 6.3 6.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein PAT1 PF09770.9 CDJ46805.1 - 4.1 5.6 20.1 4 5.6 20.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec62 PF03839.16 CDJ46805.1 - 4.3 6.8 7.2 5 6.6 7.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 CSG2 PF16965.5 CDJ46805.1 - 4.3 6.2 4.9 4.9 6.0 4.9 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Gti1_Pac2 PF09729.9 CDJ46805.1 - 5.9 6.9 12.3 8.1 6.5 12.3 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family GREB1 PF15782.5 CDJ46805.1 - 6.6 3.7 17.1 6.7 3.7 17.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SCAI PF12070.8 CDJ46805.1 - 6.8 5.4 13.2 3.3 6.5 1.4 2.0 1 1 1 2 2 2 0 Protein SCAI Dicty_REP PF05086.12 CDJ46805.1 - 8.2 4.3 9.9 8.7 4.2 9.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Spore_coat_CotO PF14153.6 CDJ46805.1 - 8.3 6.3 16.5 9.8 6.1 16.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO ALMT PF11744.8 CDJ46805.1 - 8.5 5.1 14.2 9.5 4.9 14.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ46805.1 - 8.7 5.2 14.2 9.4 5.1 14.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PTH2 PF01981.16 CDJ46806.1 - 3.6e-16 59.5 0.0 3.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 ODV-E18 PF10717.9 CDJ46806.1 - 0.16 11.8 0.4 0.24 11.3 0.4 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 AF-4 PF05110.13 CDJ46807.1 - 0.76 7.8 9.2 0.98 7.4 9.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ46807.1 - 3.3 7.3 15.9 7.1 6.2 15.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4834 PF16118.5 CDJ46809.1 - 0.0032 18.4 2.7 0.0032 18.4 2.7 3.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4834) Roughex PF06020.11 CDJ46809.1 - 1.4 7.9 9.1 3.4 6.7 9.1 1.6 1 0 0 1 1 1 0 Drosophila roughex protein AAA_23 PF13476.6 CDJ46810.1 - 0.13 12.7 36.1 0.19 12.2 36.1 1.2 1 0 0 1 1 1 0 AAA domain RAP1 PF07218.11 CDJ46810.1 - 0.71 8.1 18.4 0.87 7.8 18.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.9 CDJ46810.1 - 0.94 7.7 66.3 1.3 7.2 66.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.11 CDJ46810.1 - 8.2 6.4 33.7 9.3 6.2 33.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CENP-C_mid PF15620.6 CDJ46811.1 - 0.36 10.7 21.4 0.52 10.2 21.4 1.2 1 0 0 1 1 1 0 Centromere assembly component CENP-C middle DNMT3B-binding region GREB1 PF15782.5 CDJ46811.1 - 3.6 4.6 14.9 3.2 4.8 14.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FtsJ PF01728.19 CDJ46813.1 - 2e-57 194.2 0.0 8.7e-57 192.1 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CDJ46813.1 - 0.021 14.7 0.0 0.074 12.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ46813.1 - 0.13 12.9 0.1 1.6 9.4 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain AF-4 PF05110.13 CDJ46814.1 - 0.0041 15.3 30.2 0.0057 14.8 30.2 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein RR_TM4-6 PF06459.12 CDJ46814.1 - 0.16 11.7 20.2 0.28 11.0 20.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.6 CDJ46814.1 - 0.28 9.6 3.0 0.32 9.3 3.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MDM10 PF12519.8 CDJ46814.1 - 0.33 9.8 13.9 0.49 9.2 13.9 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 LAP1C PF05609.12 CDJ46814.1 - 0.34 10.0 21.5 0.48 9.4 21.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SART-1 PF03343.13 CDJ46814.1 - 0.45 9.0 23.4 0.63 8.5 23.4 1.2 1 0 0 1 1 1 0 SART-1 family FAM60A PF15396.6 CDJ46814.1 - 1.6 8.7 23.7 0.74 9.8 21.3 1.6 1 1 1 2 2 2 0 Protein Family FAM60A DUF2126 PF09899.9 CDJ46814.1 - 2 6.4 10.7 2.3 6.2 10.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) eIF-3_zeta PF05091.12 CDJ46814.1 - 2.5 7.0 23.9 3.5 6.5 23.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ46814.1 - 3.3 5.5 17.6 4.3 5.1 17.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 CDJ46814.1 - 3.4 6.4 18.0 5.1 5.8 18.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ46814.1 - 3.5 6.6 19.1 5 6.0 19.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF2370 PF10176.9 CDJ46814.1 - 4.3 6.9 9.7 11 5.6 9.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Caldesmon PF02029.15 CDJ46814.1 - 4.9 5.8 26.4 7 5.3 26.4 1.1 1 0 0 1 1 1 0 Caldesmon TCP PF03634.13 CDJ46814.1 - 7.3 7.1 27.5 0.85 10.2 22.3 2.0 2 0 0 2 2 2 0 TCP family transcription factor CDC45 PF02724.14 CDJ46814.1 - 9.9 4.3 18.0 15 3.7 18.0 1.2 1 0 0 1 1 1 0 CDC45-like protein SieB PF14163.6 CDJ46815.1 - 0.1 12.1 0.7 0.24 10.9 0.7 1.6 1 0 0 1 1 1 0 Super-infection exclusion protein B Questin_oxidase PF14027.6 CDJ46816.1 - 2 7.9 10.3 2.3 7.7 10.3 1.1 1 0 0 1 1 1 0 Questin oxidase-like DUF913 PF06025.12 CDJ46816.1 - 3.1 6.7 10.4 3.4 6.6 10.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 CDJ46816.1 - 3.7 6.7 7.9 4 6.6 7.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ46816.1 - 6 5.5 22.1 6.8 5.3 22.1 1.0 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 CDJ46816.1 - 6 6.9 21.2 7.2 6.7 21.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Plasmodium_Vir PF05795.11 CDJ46816.1 - 8.3 5.7 8.1 8.8 5.6 8.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Shadoo PF14999.6 CDJ46817.1 - 0.0015 18.6 0.7 0.002 18.2 0.7 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Neuregulin PF02158.15 CDJ46817.1 - 0.055 12.8 10.4 0.069 12.5 10.4 1.1 1 0 0 1 1 1 0 Neuregulin intracellular region HemX PF04375.14 CDJ46817.1 - 0.5 9.6 25.4 0.6 9.3 25.4 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase EutA PF06277.11 CDJ46817.1 - 0.58 8.9 1.6 0.72 8.6 1.6 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA FAM60A PF15396.6 CDJ46817.1 - 0.87 9.5 5.1 1 9.3 5.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Exonuc_VII_L PF02601.15 CDJ46817.1 - 1 8.9 18.7 1.2 8.7 18.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit CLN3 PF02487.17 CDJ46817.1 - 4.2 6.3 5.9 4.5 6.2 5.9 1.1 1 0 0 1 1 1 0 CLN3 protein LCE PF14672.6 CDJ46817.1 - 7.3 7.3 8.7 4 8.1 0.1 2.3 2 0 0 2 2 2 0 Late cornified envelope Presenilin PF01080.17 CDJ46817.1 - 7.4 5.2 9.6 8 5.1 9.6 1.1 1 0 0 1 1 1 0 Presenilin TPP_enzyme_N PF02776.18 CDJ46817.1 - 9.8 5.7 10.5 22 4.6 10.4 1.6 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain RskA PF10099.9 CDJ46818.1 - 0.0055 17.0 22.8 0.069 13.4 22.8 2.0 1 1 0 1 1 1 1 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ46818.1 - 0.16 10.7 11.4 0.21 10.3 11.4 1.2 1 0 0 1 1 1 0 Presenilin MDMPI_N PF11716.8 CDJ46818.1 - 0.25 12.0 14.6 0.39 11.4 14.6 1.3 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain SOG2 PF10428.9 CDJ46818.1 - 1.5 7.9 14.6 1.8 7.7 14.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 CDJ46818.1 - 7.6 5.1 16.9 8.7 4.9 16.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM199X PF15814.5 CDJ46818.1 - 8.7 5.3 10.0 10 5.0 10.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X AF-4 PF05110.13 CDJ46819.1 - 0.18 9.9 40.0 0.2 9.7 40.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SprA-related PF12118.8 CDJ46819.1 - 0.21 10.7 34.0 0.23 10.5 34.0 1.2 1 0 0 1 1 1 0 SprA-related family BSP_II PF05432.11 CDJ46819.1 - 1.8 8.2 16.9 2.5 7.7 16.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) LAP1C PF05609.12 CDJ46819.1 - 5.2 6.0 21.1 6.4 5.8 21.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RskA PF10099.9 CDJ46820.1 - 0.028 14.7 17.9 0.037 14.3 17.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SprA-related PF12118.8 CDJ46820.1 - 0.051 12.7 26.1 0.06 12.5 26.1 1.1 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.13 CDJ46820.1 - 0.18 11.8 35.7 0.21 11.6 35.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 CDJ46820.1 - 0.22 9.7 9.0 0.23 9.7 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ46820.1 - 0.28 11.0 12.5 0.33 10.7 12.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4778 PF16008.5 CDJ46820.1 - 0.33 11.0 10.2 0.34 10.9 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Nop53 PF07767.11 CDJ46820.1 - 0.54 9.6 18.8 0.63 9.4 18.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) eIF-3_zeta PF05091.12 CDJ46820.1 - 0.77 8.7 15.3 0.82 8.6 15.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF913 PF06025.12 CDJ46820.1 - 1 8.2 6.3 1.2 8.1 6.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Suf PF05843.14 CDJ46820.1 - 1.3 8.9 16.3 1.9 8.4 16.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Band_3_cyto PF07565.13 CDJ46820.1 - 1.6 8.4 9.3 2.1 8.1 9.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ46820.1 - 1.9 7.1 18.4 2.3 6.9 18.4 1.1 1 0 0 1 1 1 0 Presenilin FAM199X PF15814.5 CDJ46820.1 - 2.4 7.1 15.9 3 6.8 15.9 1.1 1 0 0 1 1 1 0 Protein family FAM199X Menin PF05053.13 CDJ46820.1 - 3.1 6.0 12.8 3.5 5.9 12.8 1.0 1 0 0 1 1 1 0 Menin ALMT PF11744.8 CDJ46820.1 - 4.8 5.9 9.1 5.2 5.8 9.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Serinc PF03348.15 CDJ46820.1 - 5.9 5.7 5.6 6.7 5.5 5.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.16 CDJ46820.1 - 6.6 6.7 10.5 7.8 6.5 10.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 CDJ46820.1 - 7.5 5.8 23.5 8.2 5.7 23.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SLC12 PF03522.15 CDJ46820.1 - 8.6 5.3 13.5 9.5 5.1 13.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 E1_dh PF00676.20 CDJ46824.1 - 6e-44 150.2 0.0 1.4e-43 148.9 0.0 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 CDJ46824.1 - 0.00023 20.7 0.0 0.00055 19.5 0.0 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Orf78 PF06024.12 CDJ46824.1 - 0.16 12.3 0.1 0.16 12.3 0.1 4.5 2 1 2 4 4 4 0 Orf78 (ac78) RskA PF10099.9 CDJ46824.1 - 1.5 9.0 57.2 0.28 11.4 9.0 5.1 4 1 0 4 4 4 0 Anti-sigma-K factor rskA LRR_9 PF14580.6 CDJ46826.1 - 3.9e-09 36.3 0.7 2.7e-08 33.5 1.0 2.2 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 CDJ46826.1 - 1.1e-05 25.7 5.6 0.033 14.6 0.1 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ46826.1 - 0.00048 19.8 10.6 0.085 12.6 0.2 3.3 3 0 0 3 3 3 2 Leucine rich repeat SID-1_RNA_chan PF13965.6 CDJ46826.1 - 0.0023 16.4 1.5 0.0093 14.4 1.5 1.8 1 1 0 1 1 1 1 dsRNA-gated channel SID-1 SDA1 PF05285.12 CDJ46826.1 - 0.0046 16.4 39.9 0.0089 15.5 39.9 1.4 1 0 0 1 1 1 1 SDA1 eIF-3_zeta PF05091.12 CDJ46826.1 - 4.5 6.1 22.6 6.1 5.7 22.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Utp14 PF04615.13 CDJ46828.1 - 0.00049 18.8 16.1 0.00049 18.8 16.1 4.6 2 2 1 4 4 4 1 Utp14 protein DUF2722 PF10846.8 CDJ46828.1 - 0.003 16.6 11.0 0.003 16.6 11.0 10.3 6 2 3 9 9 9 3 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ46829.1 - 0.00073 19.7 47.6 0.00094 19.3 47.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ46829.1 - 0.0097 14.6 37.5 0.012 14.3 37.5 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4401 PF14351.6 CDJ46829.1 - 0.011 15.1 4.1 0.021 14.2 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) DUF1644 PF07800.12 CDJ46829.1 - 0.015 15.4 5.0 0.015 15.4 5.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) SprA-related PF12118.8 CDJ46829.1 - 0.02 14.1 36.2 0.031 13.4 36.2 1.3 1 0 0 1 1 1 0 SprA-related family MMADHC PF10229.9 CDJ46829.1 - 0.046 13.5 9.0 0.067 12.9 9.1 1.3 1 1 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein DUF5523 PF17661.1 CDJ46829.1 - 0.046 13.4 10.0 0.067 12.9 10.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) V_ATPase_I PF01496.19 CDJ46829.1 - 0.056 11.4 8.6 0.068 11.1 8.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OATP PF03137.20 CDJ46829.1 - 0.1 10.9 5.7 0.0065 14.8 1.2 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PAT1 PF09770.9 CDJ46829.1 - 0.26 9.5 30.6 0.3 9.3 30.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 2HCT PF03390.15 CDJ46829.1 - 0.37 9.4 2.8 0.44 9.1 2.8 1.1 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Glt_symporter PF03616.14 CDJ46829.1 - 0.37 9.4 1.2 0.46 9.1 1.2 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter Hamartin PF04388.12 CDJ46829.1 - 0.37 9.4 24.7 0.47 9.1 24.7 1.0 1 0 0 1 1 1 0 Hamartin protein eIF-3_zeta PF05091.12 CDJ46829.1 - 0.77 8.7 19.4 1 8.2 19.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DcuA_DcuB PF03605.14 CDJ46829.1 - 1 8.2 9.5 1.4 7.8 9.5 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter SOG2 PF10428.9 CDJ46829.1 - 1.1 8.4 25.6 1.3 8.1 25.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MDFI PF15316.6 CDJ46829.1 - 2.8 8.0 21.3 0.022 14.9 8.9 2.1 2 0 0 2 2 2 0 MyoD family inhibitor DUF3584 PF12128.8 CDJ46829.1 - 7.3 4.0 28.1 9.1 3.6 28.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NifQ PF04891.12 CDJ46829.1 - 9.1 6.6 15.2 5.2 7.4 12.8 1.7 1 1 1 2 2 2 0 NifQ zf_CCCH_4 PF18345.1 CDJ46830.1 - 0.00042 20.3 4.6 0.082 13.0 1.1 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CDJ46830.1 - 0.007 16.2 5.2 0.11 12.5 1.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CDJ46830.1 - 0.023 15.2 1.3 2.4 8.8 0.1 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CDJ46830.1 - 0.1 12.4 2.8 0.5 10.2 0.9 2.2 2 0 0 2 2 2 0 CCCH-type zinc finger oligo_HPY PF08352.12 CDJ46830.1 - 0.15 12.6 2.6 0.3 11.6 0.4 2.8 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region ANAPC4_WD40 PF12894.7 CDJ46831.1 - 0.0012 19.1 0.1 0.03 14.6 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ46831.1 - 0.0026 18.6 12.8 0.25 12.3 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Methyltransf_12 PF08242.12 CDJ46831.1 - 0.0053 17.5 1.0 0.0053 17.5 1.0 4.4 4 1 0 5 5 5 1 Methyltransferase domain Hydrolase_4 PF12146.8 CDJ46833.1 - 6.2e-15 55.1 25.1 3.3e-06 26.6 0.3 5.1 4 1 1 5 5 5 4 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ46833.1 - 0.0089 15.7 0.0 0.0089 15.7 0.0 4.6 4 2 1 5 5 5 1 alpha/beta hydrolase fold Pex14_N PF04695.13 CDJ46834.1 - 0.023 15.3 12.1 0.023 15.3 12.1 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CDJ46834.1 - 0.052 12.3 7.7 0.014 14.2 2.6 2.0 2 0 0 2 2 2 0 Presenilin DUF2681 PF10883.8 CDJ46834.1 - 2.7 8.5 0.0 2.7 8.5 0.0 5.1 4 1 1 5 5 5 0 Protein of unknown function (DUF2681) EPL1 PF10513.9 CDJ46834.1 - 2.7 8.4 11.4 1.4 9.3 4.6 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Connexin PF00029.19 CDJ46834.1 - 4.4 7.0 4.5 2.3 7.9 1.0 2.0 2 0 0 2 2 2 0 Connexin Hydin_ADK PF17213.3 CDJ46834.1 - 6.3 7.0 10.9 1.7 8.9 4.7 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain CPSF100_C PF13299.6 CDJ46834.1 - 9 6.4 9.6 36 4.5 6.2 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4407 PF14362.6 CDJ46834.1 - 9.3 5.5 14.8 37 3.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mo25 PF08569.11 CDJ46835.1 - 0.33 10.3 2.1 0.66 9.3 2.1 1.4 1 0 0 1 1 1 0 Mo25-like DUF948 PF06103.11 CDJ46835.1 - 1.6 9.0 6.0 30 5.0 2.6 3.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1805 PF08827.11 CDJ46836.1 - 0.18 12.1 1.4 0.93 9.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) PLU-1 PF08429.11 CDJ46837.1 - 3.4e-05 23.2 7.9 0.00055 19.2 4.8 9.6 8 3 1 10 10 10 3 PLU-1-like protein PHD PF00628.29 CDJ46837.1 - 0.066 13.1 0.1 0.23 11.4 0.1 1.9 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 CDJ46837.1 - 0.13 12.2 0.2 0.31 11.0 0.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AP_endonuc_2 PF01261.24 CDJ46838.1 - 0.0042 16.5 1.1 0.067 12.6 0.0 2.6 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Spectrin PF00435.21 CDJ46838.1 - 0.059 13.9 0.3 0.059 13.9 0.3 4.1 4 0 0 4 4 4 0 Spectrin repeat Focal_AT PF03623.13 CDJ46838.1 - 0.32 11.0 2.5 0.85 9.6 0.0 3.0 3 0 0 3 3 3 0 Focal adhesion targeting region LUC7 PF03194.15 CDJ46838.1 - 3.3 7.3 17.4 0.26 10.9 4.7 3.2 3 0 0 3 3 3 0 LUC7 N_terminus Syntaxin-6_N PF09177.11 CDJ46838.1 - 3.7 8.1 6.8 40 4.9 0.1 4.0 5 0 0 5 5 5 0 Syntaxin 6, N-terminal PMC2NT PF08066.12 CDJ46839.1 - 2.8 8.7 10.2 8.1 7.2 0.0 4.6 5 0 0 5 5 5 0 PMC2NT (NUC016) domain SR-25 PF10500.9 CDJ46841.1 - 0.065 12.8 32.7 0.99 9.0 2.2 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Transposase_24 PF03004.14 CDJ46841.1 - 5.4 7.1 9.7 4.1 7.5 0.1 3.1 3 0 0 3 3 3 0 Plant transposase (Ptta/En/Spm family) Nop14 PF04147.12 CDJ46842.1 - 0.16 10.2 39.1 0.22 9.7 39.1 1.2 1 0 0 1 1 1 0 Nop14-like family AbLIM_anchor PF16182.5 CDJ46842.1 - 0.39 10.5 31.4 0.6 9.9 31.4 1.2 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM AF-4 PF05110.13 CDJ46842.1 - 2.9 5.9 60.2 0.1 10.7 3.2 2.4 2 0 0 2 2 2 0 AF-4 proto-oncoprotein PNISR PF15996.5 CDJ46842.1 - 6.5 7.0 58.0 1.4e+02 2.6 58.4 2.4 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR RskA PF10099.9 CDJ46843.1 - 0.0014 19.0 13.9 0.0018 18.6 13.9 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ46843.1 - 0.0023 17.6 10.7 0.0025 17.5 10.7 1.1 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ46843.1 - 0.0033 17.5 14.9 0.0036 17.3 14.9 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ46843.1 - 0.016 14.2 8.1 0.019 14.0 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF5349 PF17298.2 CDJ46843.1 - 0.035 13.9 3.2 0.043 13.6 3.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) RAB3GAP2_N PF14655.6 CDJ46843.1 - 0.051 12.8 2.8 0.061 12.6 2.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3487 PF11990.8 CDJ46843.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF5521 PF17659.1 CDJ46843.1 - 0.43 8.4 2.8 0.44 8.3 2.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Sec62 PF03839.16 CDJ46843.1 - 0.53 9.8 4.0 0.65 9.5 4.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Exonuc_VII_L PF02601.15 CDJ46843.1 - 0.56 9.7 10.1 0.66 9.5 10.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit BAF1_ABF1 PF04684.13 CDJ46843.1 - 0.76 8.8 7.4 0.87 8.6 7.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UPF0560 PF10577.9 CDJ46843.1 - 0.86 8.0 8.6 0.95 7.9 8.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ndc1_Nup PF09531.10 CDJ46843.1 - 0.91 8.1 3.8 0.93 8.1 3.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spore_coat_CotO PF14153.6 CDJ46843.1 - 1.1 9.2 13.9 1.4 8.8 13.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF3391 PF11871.8 CDJ46843.1 - 1.1 9.7 12.7 1.7 9.2 12.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF4834 PF16118.5 CDJ46843.1 - 1.6 9.8 5.2 2.5 9.1 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PepSY_TM PF03929.16 CDJ46843.1 - 1.7 8.2 4.5 1.9 8.1 4.5 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Presenilin PF01080.17 CDJ46843.1 - 2.8 6.6 6.4 3 6.5 6.4 1.0 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ46844.1 - 0.00057 19.0 17.8 0.00057 19.0 17.8 5.4 3 2 1 4 4 4 1 Protein of unknown function (DUF2722) Methyltransf_23 PF13489.6 CDJ46845.1 - 6.9e-13 48.8 0.0 8.8e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ46845.1 - 8.5e-11 42.4 0.0 1.2e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ46845.1 - 7.2e-09 36.2 0.0 1.2e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ46845.1 - 6.9e-08 32.1 0.0 8e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CDJ46845.1 - 1.9e-06 28.5 0.0 2.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ46845.1 - 0.00059 19.7 0.0 0.00073 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PAXIP1_C PF15364.6 CDJ46846.1 - 0.29 11.5 21.6 0.14 12.5 7.9 3.4 3 0 0 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF3446 PF11928.8 CDJ46846.1 - 0.71 10.2 16.5 1.1 9.6 5.6 3.8 3 0 0 3 3 3 0 Early growth response N-terminal domain Connexin PF00029.19 CDJ46846.1 - 2.9 7.6 13.5 1.6 8.4 7.3 2.5 2 0 0 2 2 2 0 Connexin MPM1 PF17234.2 CDJ46846.1 - 4.9 7.4 24.8 9.1 6.5 12.8 2.9 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 XRN1_D2_D3 PF18334.1 CDJ46846.1 - 5.3 7.3 7.7 2.5 8.4 0.3 3.0 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D2/D3 domain tRNA-synt_1g PF09334.11 CDJ46847.1 - 1.6e-12 46.9 0.4 2.6e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CDJ46847.1 - 0.0016 16.8 0.0 0.0016 16.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ46847.1 - 0.0023 17.9 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Neur_chan_memb PF02932.16 CDJ46847.1 - 0.1 12.6 2.7 0.11 12.5 2.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Folate_carrier PF01770.18 CDJ46847.1 - 0.39 9.4 0.9 0.52 9.0 0.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier TFIIA PF03153.13 CDJ46847.1 - 0.53 10.2 28.9 0.7 9.8 28.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ46847.1 - 5.6 6.5 38.8 7.9 6.0 38.8 1.2 1 0 0 1 1 1 0 Spt20 family OATP PF03137.20 CDJ46847.1 - 7 4.8 9.3 9.4 4.4 9.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1077 PF06417.12 CDJ46848.1 - 4e-24 84.9 0.1 2.2e-23 82.5 0.1 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Spt20 PF12090.8 CDJ46848.1 - 0.00065 19.4 9.2 0.00065 19.4 9.2 10.7 8 1 0 8 8 8 5 Spt20 family RT_RNaseH_2 PF17919.1 CDJ46850.1 - 2.3e-25 88.6 0.1 4e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ46850.1 - 2.3e-15 56.8 0.0 4.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ46850.1 - 1e-08 35.4 0.1 2.9e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDJ46850.1 - 0.061 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain RskA PF10099.9 CDJ46851.1 - 0.00055 20.3 17.4 0.00055 20.3 17.4 8.3 1 1 3 5 5 5 1 Anti-sigma-K factor rskA VIT1 PF01988.19 CDJ46851.1 - 0.0021 18.0 5.9 0.0021 18.0 5.9 4.7 3 1 1 4 4 4 1 VIT family DUF445 PF04286.12 CDJ46852.1 - 0.012 15.4 26.9 0.018 14.9 26.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) UBA_e1_thiolCys PF10585.9 CDJ46853.1 - 8.2e-12 45.6 0.1 2.5e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site ThiF PF00899.21 CDJ46853.1 - 3e-06 26.8 0.0 3.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Cu_amine_oxid PF01179.20 CDJ46854.1 - 9.6e-31 107.1 0.0 9.6e-31 107.1 0.0 2.7 2 1 0 2 2 2 1 Copper amine oxidase, enzyme domain MAM PF00629.23 CDJ46854.1 - 1.3e-26 93.4 0.0 2.6e-22 79.5 0.0 4.2 4 0 0 4 4 4 2 MAM domain, meprin/A5/mu Pkinase_fungal PF17667.1 CDJ46854.1 - 4.2 6.0 16.2 0.53 9.0 9.6 2.2 2 0 0 2 2 2 0 Fungal protein kinase LMBR1 PF04791.16 CDJ46854.1 - 5.7 5.7 15.5 10 4.9 15.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Methyltransf_25 PF13649.6 CDJ46855.1 - 4e-10 40.3 0.3 1.2e-09 38.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ46855.1 - 4.1e-09 36.4 0.0 6.7e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ46855.1 - 8.5e-09 35.9 0.1 3e-08 34.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CDJ46855.1 - 9.8e-07 28.4 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 CDJ46855.1 - 0.00018 20.5 0.0 0.00022 20.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 CDJ46855.1 - 0.0014 18.4 0.0 0.0023 17.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ46855.1 - 0.0032 17.5 0.0 0.0042 17.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 CDJ46855.1 - 0.0054 16.3 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 CDJ46855.1 - 0.017 15.9 0.0 0.037 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ46855.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 CDJ46855.1 - 0.084 12.4 1.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 CDJ46855.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF1604 PF07713.13 CDJ46856.1 - 5.6e-06 26.1 0.1 2.7e-05 23.9 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) DUF2722 PF10846.8 CDJ46857.1 - 9.4e-06 24.8 17.0 1.4e-05 24.3 17.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Sec1 PF00995.23 CDJ46857.1 - 0.00041 19.7 0.4 0.00046 19.5 0.4 1.1 1 0 0 1 1 1 1 Sec1 family TFIIA PF03153.13 CDJ46857.1 - 0.00064 19.8 29.1 0.0011 19.1 29.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Rxt3 PF08642.10 CDJ46857.1 - 0.0015 19.3 1.9 0.0038 18.0 1.9 1.6 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 DUF4834 PF16118.5 CDJ46857.1 - 0.0045 17.9 11.6 0.0084 17.1 8.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) MDM10 PF12519.8 CDJ46857.1 - 0.035 13.0 3.2 0.041 12.7 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CDC45 PF02724.14 CDJ46857.1 - 0.042 12.2 6.9 0.073 11.3 6.9 1.3 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 CDJ46857.1 - 0.042 13.5 0.7 0.042 13.5 0.7 2.0 2 0 0 2 2 2 0 FAM176 family SpoIIP PF07454.11 CDJ46857.1 - 0.043 13.3 7.3 0.063 12.7 7.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ABC2_membrane_2 PF12679.7 CDJ46857.1 - 0.05 12.9 0.2 0.067 12.5 0.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein RED_N PF07808.13 CDJ46857.1 - 0.069 12.7 9.5 0.12 12.0 9.5 1.5 1 0 0 1 1 1 0 RED-like protein N-terminal region eIF-3_zeta PF05091.12 CDJ46857.1 - 0.082 11.9 13.4 0.13 11.2 13.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) OATP PF03137.20 CDJ46857.1 - 0.096 11.0 1.1 0.12 10.7 1.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AIF_C PF14721.6 CDJ46857.1 - 0.11 12.8 4.6 0.34 11.3 4.6 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Otopetrin PF03189.13 CDJ46857.1 - 0.13 11.1 0.2 0.12 11.2 0.2 1.1 1 0 0 1 1 1 0 Otopetrin FHIPEP PF00771.20 CDJ46857.1 - 0.13 10.7 2.7 0.2 10.1 2.7 1.2 1 0 0 1 1 1 0 FHIPEP family DUF775 PF05603.12 CDJ46857.1 - 0.2 11.2 11.1 0.41 10.1 11.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) G0-G1_switch_2 PF15103.6 CDJ46857.1 - 0.2 12.1 5.0 0.52 10.8 5.0 1.7 1 0 0 1 1 1 0 G0/G1 switch protein 2 EPL1 PF10513.9 CDJ46857.1 - 0.2 12.0 10.2 0.43 11.0 10.2 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like TERB2 PF15101.6 CDJ46857.1 - 0.21 11.6 15.3 0.41 10.7 15.3 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EIIBC-GUT_N PF03612.14 CDJ46857.1 - 0.23 11.2 7.2 0.48 10.2 7.2 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Connexin PF00029.19 CDJ46857.1 - 0.26 11.0 6.2 0.45 10.2 6.2 1.3 1 0 0 1 1 1 0 Connexin DUF3381 PF11861.8 CDJ46857.1 - 0.28 11.0 11.2 0.45 10.3 11.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CLN3 PF02487.17 CDJ46857.1 - 0.38 9.7 4.2 0.55 9.2 4.2 1.2 1 0 0 1 1 1 0 CLN3 protein SLC12 PF03522.15 CDJ46857.1 - 0.49 9.4 7.7 0.65 8.9 7.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 CDJ46857.1 - 0.5 8.4 7.0 0.67 8.0 7.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Band_3_cyto PF07565.13 CDJ46857.1 - 0.55 10.0 7.5 0.86 9.4 7.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4746 PF15928.5 CDJ46857.1 - 0.7 9.3 6.9 0.23 10.8 4.5 1.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4746) SID-1_RNA_chan PF13965.6 CDJ46857.1 - 0.72 8.2 3.2 0.95 7.8 3.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peroxin-13_N PF04088.13 CDJ46857.1 - 0.94 9.7 4.3 2.4 8.4 4.3 1.7 1 0 0 1 1 1 0 Peroxin 13, N-terminal region TFB6 PF17110.5 CDJ46857.1 - 1.1 9.0 7.6 1.9 8.2 7.6 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Tom22 PF04281.13 CDJ46857.1 - 1.1 9.0 10.1 0.041 13.7 4.0 1.7 2 0 0 2 2 1 0 Mitochondrial import receptor subunit Tom22 DUF3464 PF11947.8 CDJ46857.1 - 1.2 8.9 12.2 3.2 7.5 12.2 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Ureide_permease PF07168.11 CDJ46857.1 - 1.2 7.8 5.7 1.5 7.5 0.8 2.3 2 0 0 2 2 2 0 Ureide permease Sec62 PF03839.16 CDJ46857.1 - 1.4 8.3 5.2 2.1 7.8 5.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Folate_carrier PF01770.18 CDJ46857.1 - 1.5 7.5 3.8 2 7.0 3.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF2828 PF11443.8 CDJ46857.1 - 1.7 6.7 9.5 2.5 6.1 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) ALMT PF11744.8 CDJ46857.1 - 1.9 7.2 6.6 2.5 6.8 6.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PIP5K PF01504.18 CDJ46857.1 - 2.5 7.3 8.8 0.99 8.6 6.5 1.4 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase MMR1 PF08505.10 CDJ46857.1 - 2.7 8.2 16.8 0.41 10.9 12.9 1.6 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF4770 PF15994.5 CDJ46857.1 - 2.8 8.1 12.7 4.2 7.6 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) WASH-7_C PF14746.6 CDJ46857.1 - 3.8 7.2 10.1 5.9 6.6 10.1 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal PAT1 PF09770.9 CDJ46857.1 - 4 5.6 24.4 5.6 5.1 24.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4199 PF13858.6 CDJ46857.1 - 7.5 6.9 5.0 12 6.2 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) UPF0560 PF10577.9 CDJ46857.1 - 9.7 4.5 19.5 18 3.7 19.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Spt20 PF12090.8 CDJ46858.1 - 0.28 10.8 52.8 0.33 10.5 52.8 1.1 1 0 0 1 1 1 0 Spt20 family Paf1 PF03985.13 CDJ46858.1 - 7.3 5.5 20.1 7.7 5.4 20.1 1.0 1 0 0 1 1 1 0 Paf1 TMEM51 PF15345.6 CDJ46858.1 - 7.4 6.3 20.0 11 5.8 20.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 CNDH2_M PF16869.5 CDJ46858.1 - 8.5 7.1 13.7 9.4 6.9 13.7 1.1 1 0 0 1 1 1 0 PF16858 Trypsin_2 PF13365.6 CDJ46859.1 - 3.3e-21 76.7 2.0 1.9e-20 74.3 2.0 2.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CDJ46859.1 - 1.3e-12 48.1 0.0 4.3e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Trypsin VirK PF06903.12 CDJ46859.1 - 0.086 12.9 0.0 25 5.0 0.0 2.8 2 0 0 2 2 2 0 VirK protein COX6B PF02297.17 CDJ46860.1 - 4.1e-05 23.7 5.2 6.1e-05 23.2 5.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb MCCD1 PF15707.5 CDJ46864.1 - 0.0042 17.5 12.8 0.9 10.0 0.2 3.9 4 0 0 4 4 4 3 Mitochondrial coiled-coil domain protein 1 THEG PF14912.6 CDJ46864.1 - 0.052 14.0 0.2 40 4.8 0.0 3.8 4 0 0 4 4 4 0 Testicular haploid expressed repeat Sin_N PF04801.13 CDJ46865.1 - 6.9e-05 22.2 0.1 6.9e-05 22.2 0.1 9.8 5 1 3 9 9 9 2 Sin-like protein conserved region RskA PF10099.9 CDJ46865.1 - 0.0082 16.5 0.0 0.0082 16.5 0.0 22.8 7 7 10 18 18 18 4 Anti-sigma-K factor rskA DUF4512 PF14975.6 CDJ46865.1 - 0.66 10.8 0.0 0.66 10.8 0.0 8.9 10 1 0 10 10 10 0 Domain of unknown function (DUF4512) Presenilin PF01080.17 CDJ46866.1 - 0.07 11.9 9.4 0.076 11.8 9.4 1.0 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDJ46866.1 - 0.091 11.6 18.5 0.097 11.5 18.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ46866.1 - 0.22 10.0 22.0 0.26 9.8 22.0 1.2 1 0 0 1 1 1 0 Macoilin family AIF_C PF14721.6 CDJ46866.1 - 0.3 11.4 3.3 0.43 10.9 3.3 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RNA_pol_Rpc4 PF05132.14 CDJ46866.1 - 0.5 10.8 8.1 0.76 10.2 8.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Striatin PF08232.12 CDJ46866.1 - 0.82 10.3 7.3 0.95 10.0 7.3 1.1 1 0 0 1 1 1 0 Striatin family ATP11 PF06644.11 CDJ46866.1 - 0.86 9.3 6.6 1.1 9.0 6.6 1.3 1 0 0 1 1 1 0 ATP11 protein DUF4228 PF14009.6 CDJ46866.1 - 1 9.7 14.8 1.2 9.5 14.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) ANAPC1 PF12859.7 CDJ46866.1 - 1.2 9.7 11.5 1.4 9.5 11.5 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 CPSF100_C PF13299.6 CDJ46866.1 - 1.2 9.3 5.5 1.4 9.1 5.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hid1 PF12722.7 CDJ46866.1 - 1.4 6.9 7.9 1.4 6.9 7.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SpoIIIAH PF12685.7 CDJ46866.1 - 1.4 8.7 14.7 1.7 8.4 14.7 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein NPR3 PF03666.13 CDJ46866.1 - 1.5 7.5 11.7 1.7 7.4 11.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cyto_heme_lyase PF01265.17 CDJ46866.1 - 1.5 8.3 7.5 1.6 8.3 7.5 1.0 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Sec3_C PF09763.9 CDJ46866.1 - 1.5 7.1 10.2 1.5 7.1 10.2 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 SRP-alpha_N PF04086.13 CDJ46866.1 - 1.5 8.6 12.9 1.6 8.5 12.9 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pkinase_fungal PF17667.1 CDJ46866.1 - 1.7 7.3 5.9 1.7 7.3 5.9 1.0 1 0 0 1 1 1 0 Fungal protein kinase SPX PF03105.19 CDJ46866.1 - 3.4 7.5 19.2 3.9 7.3 19.2 1.0 1 0 0 1 1 1 0 SPX domain DUF4834 PF16118.5 CDJ46866.1 - 4.2 8.4 5.9 5.8 7.9 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MMU163 PF17119.5 CDJ46866.1 - 4.4 6.4 8.3 5.3 6.1 8.3 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis IHABP4_N PF16174.5 CDJ46866.1 - 4.8 7.8 8.6 7.3 7.2 8.6 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal API5 PF05918.11 CDJ46866.1 - 6.5 5.4 9.8 7.6 5.2 9.8 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SOBP PF15279.6 CDJ46866.1 - 6.9 7.2 12.1 6.5 7.3 12.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GREB1 PF15782.5 CDJ46866.1 - 7.1 3.6 14.3 6.9 3.6 14.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Tmemb_cc2 PF10267.9 CDJ46866.1 - 7.6 5.6 12.2 7.8 5.5 12.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MAP65_ASE1 PF03999.12 CDJ46866.1 - 8 5.0 12.8 7.8 5.1 12.8 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF5427 PF10310.9 CDJ46867.1 - 0.0025 16.8 19.1 0.003 16.6 19.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) RskA PF10099.9 CDJ46867.1 - 0.027 14.8 0.0 0.027 14.8 0.0 3.8 1 1 2 3 3 2 0 Anti-sigma-K factor rskA SARAF PF06682.12 CDJ46867.1 - 0.054 13.1 14.6 0.28 10.8 0.2 2.2 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Peptidase_M56 PF05569.11 CDJ46867.1 - 0.14 11.3 0.3 0.31 10.2 0.1 1.8 2 0 0 2 2 2 0 BlaR1 peptidase M56 OATP PF03137.20 CDJ46867.1 - 0.4 8.9 6.1 3.5 5.8 3.4 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2235 PF09994.9 CDJ46867.1 - 0.43 9.9 7.0 0.16 11.3 0.8 2.1 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyco_hydro_47 PF01532.20 CDJ46867.1 - 0.85 8.4 4.0 1.3 7.9 4.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 47 DUF572 PF04502.13 CDJ46867.1 - 2.5 7.7 19.9 3.6 7.1 19.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) YjbH PF06082.11 CDJ46867.1 - 3.8 6.2 18.2 4.7 5.9 18.2 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Folate_carrier PF01770.18 CDJ46867.1 - 4.8 5.8 7.8 1.3 7.7 2.5 2.1 2 0 0 2 2 2 0 Reduced folate carrier WTX PF09422.10 CDJ46867.1 - 6.5 5.7 15.3 8.6 5.3 15.3 1.1 1 0 0 1 1 1 0 WTX protein AAA_6 PF12774.7 CDJ46867.1 - 6.9 5.5 12.6 0.1 11.6 5.4 1.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Biotin_lipoyl PF00364.22 CDJ46868.1 - 1.7e-33 114.3 1.7 9e-16 57.5 0.1 2.2 2 0 0 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDJ46868.1 - 4.7e-10 39.1 8.5 0.00053 19.8 0.0 4.2 3 1 1 4 4 4 3 Biotin-lipoyl like HlyD_3 PF13437.6 CDJ46868.1 - 2.1e-05 25.1 4.3 0.77 10.5 0.0 4.2 2 2 1 4 4 4 2 HlyD family secretion protein DUF2118 PF09891.9 CDJ46868.1 - 0.0067 16.4 0.5 0.92 9.5 0.0 3.1 2 2 2 4 4 4 1 Uncharacterized protein conserved in archaea (DUF2118) PTS_EIIA_1 PF00358.20 CDJ46868.1 - 0.0084 15.9 0.1 1.8 8.3 0.0 3.0 2 1 1 3 3 3 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 CDJ46868.1 - 0.013 15.7 2.0 11 6.3 0.0 3.7 2 2 1 3 3 3 0 Peptidase family M23 HlyD_D23 PF16576.5 CDJ46868.1 - 0.013 14.8 3.9 3.2 6.9 0.0 3.5 3 1 1 4 4 4 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion QRPTase_N PF02749.16 CDJ46868.1 - 0.033 14.3 8.1 2.8 8.1 0.1 4.0 3 1 1 4 4 4 0 Quinolinate phosphoribosyl transferase, N-terminal domain GCV_H PF01597.19 CDJ46868.1 - 0.067 13.1 6.1 2.4 8.1 0.0 2.8 3 0 0 3 3 3 0 Glycine cleavage H-protein SR-25 PF10500.9 CDJ46869.1 - 0.004 16.8 15.1 0.004 16.8 15.1 4.4 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein DUF4342 PF14242.6 CDJ46869.1 - 0.038 14.0 0.1 0.038 14.0 0.1 8.5 8 1 0 9 9 9 0 Domain of unknown function (DUF4342) UPF0176_N PF17773.1 CDJ46869.1 - 3.4 8.1 5.3 0.63 10.4 0.2 2.5 2 0 0 2 2 2 0 UPF0176 acylphosphatase like domain Metallophos PF00149.28 CDJ46870.1 - 1.8e-40 139.7 0.2 2.4e-40 139.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ46870.1 - 1.3e-20 73.6 0.2 4.1e-20 71.9 0.1 2.0 2 0 0 2 2 1 1 Serine-threonine protein phosphatase N-terminal domain Spt20 PF12090.8 CDJ46870.1 - 0.00013 21.6 13.2 0.00019 21.1 13.2 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ46870.1 - 0.0031 16.5 10.7 0.0039 16.2 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) SpoIIP PF07454.11 CDJ46870.1 - 0.046 13.2 0.1 0.063 12.7 0.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FAM150 PF15129.6 CDJ46870.1 - 0.056 13.6 2.2 0.11 12.6 2.2 1.4 1 0 0 1 1 1 0 FAM150 family AAA_23 PF13476.6 CDJ46870.1 - 0.068 13.7 4.2 0.097 13.2 4.2 1.2 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.13 CDJ46870.1 - 0.13 12.9 10.2 0.21 12.2 10.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM51 PF15345.6 CDJ46870.1 - 0.21 11.4 3.2 0.28 11.0 3.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 UPF0560 PF10577.9 CDJ46870.1 - 0.66 8.4 8.0 0.87 8.0 8.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Presenilin PF01080.17 CDJ46870.1 - 0.83 8.4 2.7 1.2 7.8 2.7 1.2 1 0 0 1 1 1 0 Presenilin Nitroreductase PF00881.24 CDJ46870.1 - 2.3 8.2 10.0 3.6 7.6 10.0 1.2 1 0 0 1 1 1 0 Nitroreductase family EIF4E-T PF10477.9 CDJ46870.1 - 3.6 6.3 11.1 4.6 5.9 11.1 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E TERB2 PF15101.6 CDJ46870.1 - 4.8 7.2 9.9 7.7 6.5 9.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SR-25 PF10500.9 CDJ46871.1 - 0.00026 20.7 9.5 0.00026 20.7 9.5 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ46871.1 - 0.0042 16.7 58.5 0.029 14.0 18.9 2.4 2 0 0 2 2 2 2 Spt20 family Tim54 PF11711.8 CDJ46871.1 - 0.19 10.5 11.9 0.21 10.4 0.8 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 CDJ46871.1 - 0.28 10.6 13.2 0.5 9.8 5.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 CDJ46871.1 - 0.4 10.6 66.2 0.44 10.5 24.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit OATP PF03137.20 CDJ46871.1 - 0.59 8.4 6.7 3.7 5.7 0.2 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAM60A PF15396.6 CDJ46871.1 - 0.74 9.8 12.9 3.5 7.6 7.0 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Thg1C PF14413.6 CDJ46871.1 - 0.76 10.0 10.1 13 6.0 0.1 2.5 2 0 0 2 2 2 0 Thg1 C terminal domain CLN3 PF02487.17 CDJ46871.1 - 0.81 8.7 10.6 3 6.8 3.8 2.1 2 0 0 2 2 2 0 CLN3 protein EFTUD2 PF16004.5 CDJ46871.1 - 1.1 9.9 16.2 0.81 10.3 5.5 2.4 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus MAM33 PF02330.16 CDJ46871.1 - 1.6 8.6 13.7 2.5 8.0 4.5 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein Peptidase_S49_N PF08496.10 CDJ46871.1 - 3.8 7.6 11.7 1.8 8.6 3.1 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FAM176 PF14851.6 CDJ46871.1 - 3.9 7.1 8.6 7.9 6.1 3.2 2.3 2 0 0 2 2 2 0 FAM176 family Connexin PF00029.19 CDJ46871.1 - 5.3 6.7 10.8 2.2 8.0 3.3 2.3 2 0 0 2 2 2 0 Connexin DUF4770 PF15994.5 CDJ46871.1 - 5.5 7.2 21.9 3.2 7.9 7.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) XAP5 PF04921.14 CDJ46871.1 - 7.2 6.3 15.3 3.9 7.2 5.9 2.2 2 0 0 2 2 2 0 XAP5, circadian clock regulator PRC2_HTH_1 PF18118.1 CDJ46871.1 - 7.3 7.5 12.1 12 6.7 4.4 2.4 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain ALMT PF11744.8 CDJ46871.1 - 8.4 5.1 17.1 0.098 11.5 2.1 2.1 1 1 1 2 2 2 0 Aluminium activated malate transporter Spem1 PF15670.5 CDJ46871.1 - 9.9 5.7 21.2 0.32 10.5 9.6 2.3 2 0 0 2 2 2 0 Spermatid maturation protein 1 RskA PF10099.9 CDJ46872.1 - 0.00051 20.4 3.0 0.00051 20.4 3.0 1.8 2 0 0 2 2 2 1 Anti-sigma-K factor rskA DUF4357 PF14267.6 CDJ46872.1 - 0.31 11.0 0.0 0.31 11.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4357) DUF2868 PF11067.8 CDJ46872.1 - 1 8.8 9.9 1.8 8.0 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Caldesmon PF02029.15 CDJ46872.1 - 4.7 5.9 55.9 6.3 5.4 55.9 1.1 1 0 0 1 1 1 0 Caldesmon TFIIA PF03153.13 CDJ46873.1 - 0.0056 16.7 33.1 0.0056 16.7 33.1 4.2 2 2 2 4 4 4 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ46873.1 - 0.0078 16.5 10.2 0.0078 16.5 10.2 8.8 2 2 4 7 7 7 3 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ46873.1 - 0.0085 15.1 1.0 0.0085 15.1 1.0 6.7 6 1 0 6 6 6 2 Protein of unknown function (DUF2722) EOS1 PF12326.8 CDJ46873.1 - 0.42 10.5 13.7 7.1 6.5 0.3 4.4 4 1 0 4 4 4 0 N-glycosylation protein Btz PF09405.10 CDJ46875.1 - 3.9e-10 40.1 10.5 3.9e-10 40.1 10.5 2.5 3 1 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding OmpH PF03938.14 CDJ46876.1 - 2.2 8.6 9.5 0.45 10.8 5.7 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1645 PF07816.11 CDJ46877.1 - 0.00087 19.9 2.9 0.0011 19.6 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ46877.1 - 0.0055 16.4 7.6 0.0061 16.2 7.6 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ46877.1 - 0.014 14.4 9.1 0.017 14.1 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ46877.1 - 0.053 13.5 7.4 0.056 13.4 7.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1360 PF07098.11 CDJ46877.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Yip1 PF04893.17 CDJ46878.1 - 0.0027 17.4 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Yip1 domain Trypan_PARP PF05887.11 CDJ46878.1 - 0.011 15.7 12.8 0.011 15.7 12.8 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SID-1_RNA_chan PF13965.6 CDJ46878.1 - 0.44 8.9 0.7 0.84 8.0 0.7 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2076 PF09849.9 CDJ46879.1 - 0.0025 17.9 17.0 0.0042 17.2 17.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) E2F_CC-MB PF16421.5 CDJ46879.1 - 0.014 15.7 1.5 0.014 15.7 1.5 1.7 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain GET2 PF08690.10 CDJ46879.1 - 0.033 13.9 3.1 0.033 13.9 3.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Y1_Tnp PF01797.16 CDJ46879.1 - 0.042 13.9 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 Transposase IS200 like Stevor PF17410.2 CDJ46879.1 - 0.059 12.9 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TSC22 PF01166.18 CDJ46879.1 - 0.069 13.5 8.2 0.75 10.2 0.1 2.3 1 1 0 2 2 2 0 TSC-22/dip/bun family Fmp27_WPPW PF10359.9 CDJ46879.1 - 0.097 11.5 4.2 0.11 11.4 4.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Nop53 PF07767.11 CDJ46879.1 - 0.16 11.3 14.3 0.21 10.9 14.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GNT-I PF03071.15 CDJ46879.1 - 0.17 10.6 2.3 0.2 10.4 2.3 1.0 1 0 0 1 1 1 0 GNT-I family Tho2 PF11262.8 CDJ46879.1 - 0.2 10.8 3.6 0.23 10.7 3.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Macoilin PF09726.9 CDJ46879.1 - 0.22 10.0 7.6 0.25 9.9 7.6 1.2 1 0 0 1 1 1 0 Macoilin family DUF3138 PF11336.8 CDJ46879.1 - 0.23 10.0 11.1 0.26 9.9 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Phage_Mu_Gam PF07352.12 CDJ46879.1 - 0.35 10.7 8.5 0.48 10.3 8.5 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF3584 PF12128.8 CDJ46879.1 - 0.96 6.9 14.9 1.2 6.6 14.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TFIIA PF03153.13 CDJ46879.1 - 1.1 9.2 10.9 1.2 9.1 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ46879.1 - 1.2 6.9 4.6 1.2 6.9 4.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.14 CDJ46879.1 - 1.3 9.3 21.2 2 8.8 21.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Myb_DNA-binding PF00249.31 CDJ46880.1 - 1.3e-10 41.3 0.0 3.9e-10 39.8 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ46880.1 - 2.4e-06 27.7 0.0 2e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Na_trans_assoc PF06512.13 CDJ46881.1 - 0.0036 17.6 5.6 0.0036 17.6 5.6 3.7 1 1 0 2 2 2 1 Sodium ion transport-associated SR-25 PF10500.9 CDJ46881.1 - 0.0079 15.8 37.4 0.0079 15.8 37.4 5.2 3 2 2 5 5 5 1 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 CDJ46881.1 - 0.01 16.4 10.2 0.01 16.4 10.2 4.3 3 2 0 3 3 3 0 AAA domain MAP7 PF05672.11 CDJ46881.1 - 0.013 15.2 25.4 0.013 15.2 25.4 4.7 4 2 0 4 4 4 0 MAP7 (E-MAP-115) family RskA PF10099.9 CDJ46883.1 - 0.014 15.7 15.3 0.023 15.0 3.8 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA TMEM51 PF15345.6 CDJ46883.1 - 0.019 14.8 9.9 0.019 14.8 9.9 2.7 1 1 1 2 2 2 0 Transmembrane protein 51 Chorein_N PF12624.7 CDJ46883.1 - 3 8.0 13.5 5.2 7.2 1.2 2.4 2 0 0 2 2 2 0 N-terminal region of Chorein or VPS13 FSAP_sig_propep PF03032.15 CDJ46883.1 - 3.3 7.8 4.5 2.4 8.3 0.4 2.2 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide UPF0542 PF15086.6 CDJ46883.1 - 3.9 7.5 7.7 6.5 6.8 0.9 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DDE_Tnp_1_2 PF13586.6 CDJ46883.1 - 5.1 7.5 10.5 1.9 8.9 1.6 2.3 2 0 0 2 2 2 0 Transposase DDE domain DUF2489 PF10675.9 CDJ46883.1 - 7.1 6.6 26.5 4.7 7.1 9.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF2140 PF09911.9 CDJ46883.1 - 8.8 5.8 9.2 16 5.0 0.8 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) CDC45 PF02724.14 CDJ46884.1 - 0.54 8.5 20.6 0.83 7.9 20.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ46884.1 - 4.1 6.3 31.1 6.1 5.7 31.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF572 PF04502.13 CDJ46884.1 - 6.2 6.3 28.2 2.3 7.8 24.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) PAT1 PF09770.9 CDJ46884.1 - 6.8 4.8 57.9 11 4.1 57.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tetraspanin PF00335.20 CDJ46884.1 - 7.7 6.2 9.9 14 5.4 9.9 1.5 1 0 0 1 1 1 0 Tetraspanin family SOBP PF15279.6 CDJ46884.1 - 9.3 6.8 34.0 1.4 9.5 28.2 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein RdRP PF05183.12 CDJ46885.1 - 8.8e-08 31.3 0.0 8.8e-08 31.3 0.0 2.2 3 0 0 3 3 3 1 RNA dependent RNA polymerase RskA PF10099.9 CDJ46885.1 - 7.1e-05 23.2 13.1 7.1e-05 23.2 13.1 9.8 2 2 4 6 6 6 1 Anti-sigma-K factor rskA DUF4667 PF15700.5 CDJ46885.1 - 0.00023 21.4 0.0 0.00023 21.4 0.0 5.0 3 2 0 3 3 3 1 Domain of unknown function (DUF4667) Plasmodium_Vir PF05795.11 CDJ46885.1 - 3.4 7.0 0.0 3.4 7.0 0.0 3.8 2 2 1 3 3 3 0 Plasmodium vivax Vir protein Presenilin PF01080.17 CDJ46886.1 - 0.00026 19.9 26.1 0.00026 19.9 26.1 5.2 2 1 0 2 2 2 1 Presenilin SDA1 PF05285.12 CDJ46886.1 - 0.00032 20.2 15.1 0.00032 20.2 15.1 4.4 2 1 0 3 3 3 1 SDA1 SAPS PF04499.15 CDJ46886.1 - 0.00051 19.0 13.8 0.00051 19.0 13.8 3.5 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Nha1_C PF08619.10 CDJ46886.1 - 0.003 16.9 21.2 0.003 16.9 21.2 4.4 2 1 1 3 3 3 1 Alkali metal cation/H+ antiporter Nha1 C terminus Gal_mutarotas_2 PF13802.6 CDJ46886.1 - 0.0046 17.2 0.3 0.03 14.7 0.2 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like SLC12 PF03522.15 CDJ46886.1 - 6.1 5.8 61.5 0.0096 15.0 26.3 3.1 4 0 0 4 4 4 0 Solute carrier family 12 DUF1772 PF08592.11 CDJ46887.1 - 0.011 16.0 0.6 0.011 16.0 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) U1snRNP70_N PF12220.8 CDJ46887.1 - 0.043 14.5 1.7 0.043 14.5 1.7 3.3 2 1 1 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal VIT1 PF01988.19 CDJ46887.1 - 0.23 11.3 25.0 0.089 12.6 4.4 2.2 2 0 0 2 2 2 0 VIT family CD20 PF04103.15 CDJ46887.1 - 0.78 9.8 0.0 0.78 9.8 0.0 2.7 2 1 0 2 2 2 0 CD20-like family Presenilin PF01080.17 CDJ46887.1 - 1.3 7.7 38.8 0.76 8.5 9.9 2.0 2 0 0 2 2 2 0 Presenilin BAF1_ABF1 PF04684.13 CDJ46887.1 - 4 6.4 37.0 2 7.4 8.3 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF3807 PF12720.7 CDJ46887.1 - 8.2 6.7 45.9 1.5 9.0 14.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF4175 PF13779.6 CDJ46888.1 - 0.0048 14.9 17.2 0.0048 14.9 17.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4175) Pex14_N PF04695.13 CDJ46888.1 - 0.021 15.5 10.9 0.021 15.5 10.9 3.1 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ABC-3 PF00950.17 CDJ46888.1 - 0.031 13.8 1.7 0.049 13.1 1.7 1.2 1 0 0 1 1 1 0 ABC 3 transport family SpoIIIAH PF12685.7 CDJ46888.1 - 1 9.1 28.1 1.3 8.8 7.0 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF3347 PF11827.8 CDJ46888.1 - 6.6 6.9 33.9 6.1 7.0 8.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) RLL PF10036.9 CDJ46888.1 - 7.1 6.4 32.6 1.3 8.8 9.8 2.3 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein PNISR PF15996.5 CDJ46888.1 - 8.3 6.6 35.7 0.16 12.2 8.7 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DUF2722 PF10846.8 CDJ46889.1 - 0.00049 19.2 6.3 0.00049 19.2 6.3 14.5 7 4 5 12 12 12 2 Protein of unknown function (DUF2722) Hid1 PF12722.7 CDJ46890.1 - 3.2 5.8 9.5 4.2 5.4 9.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_60s PF00428.19 CDJ46891.1 - 0.016 15.7 1.2 0.016 15.7 1.2 7.0 3 2 3 6 6 6 0 60s Acidic ribosomal protein WG_beta_rep PF14903.6 CDJ46891.1 - 0.019 15.2 0.9 22 5.4 0.1 4.3 5 0 0 5 5 5 0 WG containing repeat EAGR_box PF16713.5 CDJ46891.1 - 0.4 10.4 42.9 0.092 12.4 1.4 6.2 6 0 0 6 6 6 0 Enriched in aromatic and glycine Residues box MFS_2 PF13347.6 CDJ46893.1 - 0.014 14.0 0.4 0.022 13.3 0.4 1.3 1 0 0 1 1 1 0 MFS/sugar transport protein Auxin_canalis PF05703.11 CDJ46893.1 - 0.022 14.7 27.7 0.026 14.4 27.7 1.1 1 0 0 1 1 1 0 Auxin canalisation DUF966 PF06136.13 CDJ46893.1 - 6.6 6.3 31.9 7.5 6.2 31.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Ribosomal_L12_N PF16320.5 CDJ46894.1 - 0.0027 17.4 4.7 0.0058 16.3 4.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L7/L12 dimerisation domain CbiD PF01888.17 CDJ46894.1 - 0.1 11.9 1.4 0.16 11.2 1.4 1.3 1 0 0 1 1 1 0 CbiD PNKP_ligase PF16542.5 CDJ46894.1 - 0.42 10.1 9.3 0.51 9.8 9.3 1.0 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain RAP1 PF07218.11 CDJ46894.1 - 1.1 7.4 7.0 1.1 7.5 7.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ46895.1 - 6.8e-08 32.4 23.4 6.3e-06 26.0 8.5 7.8 6 2 1 7 7 7 2 Nuclear RNA-splicing-associated protein CitMHS_2 PF16980.5 CDJ46895.1 - 0.012 14.3 0.3 0.012 14.3 0.3 2.5 2 0 0 2 2 2 0 Putative citrate transport SR-25 PF10500.9 CDJ46896.1 - 0.0023 17.6 23.7 0.0023 17.6 23.7 3.1 1 1 2 3 3 3 1 Nuclear RNA-splicing-associated protein DUF4551 PF15087.6 CDJ46896.1 - 0.12 11.2 25.7 0.14 11.0 25.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) AAA_23 PF13476.6 CDJ46896.1 - 8.3 6.9 33.2 0.75 10.3 14.7 2.3 2 0 0 2 2 2 0 AAA domain SR-25 PF10500.9 CDJ46898.1 - 0.036 13.7 40.6 0.54 9.8 16.8 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4692 PF15763.5 CDJ46898.1 - 0.66 10.4 18.0 0.59 10.6 5.2 2.2 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) IMUP PF15761.5 CDJ46898.1 - 5.4 7.7 34.6 0.18 12.5 8.6 2.9 2 1 0 2 2 2 0 Immortalisation up-regulated protein DUF3446 PF11928.8 CDJ46898.1 - 6 7.2 25.2 1.6 9.1 4.2 3.0 4 0 0 4 4 4 0 Early growth response N-terminal domain BAF1_ABF1 PF04684.13 CDJ46899.1 - 0.00059 19.0 5.7 0.00073 18.7 5.7 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor SAPS PF04499.15 CDJ46899.1 - 0.025 13.4 7.0 0.027 13.3 7.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 CDJ46899.1 - 0.035 12.9 19.7 0.044 12.6 19.7 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ46899.1 - 0.061 13.4 11.8 0.079 13.0 11.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 CDJ46899.1 - 0.09 11.2 2.2 0.075 11.4 2.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ46899.1 - 0.16 10.8 5.9 0.14 11.0 5.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) GREB1 PF15782.5 CDJ46899.1 - 0.54 7.3 8.5 0.48 7.5 8.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NPR3 PF03666.13 CDJ46899.1 - 0.65 8.7 14.5 1 8.1 14.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pex14_N PF04695.13 CDJ46899.1 - 0.92 10.1 30.5 0.73 10.5 20.5 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peroxin-3 PF04882.12 CDJ46899.1 - 2.7 6.9 19.2 3.2 6.6 19.2 1.0 1 0 0 1 1 1 0 Peroxin-3 Apc15p PF05841.11 CDJ46899.1 - 2.8 8.8 25.6 4.9 8.0 0.7 2.5 2 0 0 2 2 2 0 Apc15p protein Tim54 PF11711.8 CDJ46899.1 - 2.8 6.6 22.0 0.26 10.0 17.6 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CENP-N PF05238.13 CDJ46899.1 - 4.1 6.6 12.0 6 6.1 12.0 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Pox_Ag35 PF03286.14 CDJ46899.1 - 5.2 6.8 17.1 0.19 11.5 11.5 1.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 CDJ46899.1 - 5.8 7.4 14.7 13 6.3 14.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4637 PF15470.6 CDJ46899.1 - 7.6 6.2 19.8 14 5.4 19.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Spt20 PF12090.8 CDJ46900.1 - 0.011 15.4 1.4 0.011 15.4 1.4 8.2 6 2 0 6 6 6 0 Spt20 family K_channel_TID PF07941.11 CDJ46900.1 - 0.015 15.8 4.4 0.015 15.8 4.4 16.9 10 4 3 13 13 13 0 Potassium channel Kv1.4 tandem inactivation domain SUIM_assoc PF16619.5 CDJ46900.1 - 0.035 14.2 0.3 0.035 14.2 0.3 8.3 6 1 1 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 DUF4667 PF15700.5 CDJ46900.1 - 0.078 13.1 0.2 0.078 13.1 0.2 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4667) DUF2722 PF10846.8 CDJ46900.1 - 0.097 11.6 61.7 0.033 13.1 3.1 7.5 8 0 0 8 8 8 0 Protein of unknown function (DUF2722) Pinin_SDK_N PF04697.13 CDJ46900.1 - 0.18 12.5 4.5 0.57 10.8 0.1 3.6 3 0 0 3 3 3 0 pinin/SDK conserved region DUF4179 PF13786.6 CDJ46900.1 - 0.85 10.1 0.0 0.85 10.1 0.0 10.6 9 2 0 9 9 9 0 Domain of unknown function (DUF4179) DUF4131 PF13567.6 CDJ46900.1 - 7.5 6.2 11.2 4.7 6.8 0.9 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) EF-hand_1 PF00036.32 CDJ46901.1 - 2.2e-05 23.7 0.0 0.00024 20.4 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CDJ46901.1 - 9.1e-05 22.1 0.0 0.00076 19.2 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CDJ46901.1 - 0.018 15.4 0.5 0.083 13.3 0.0 2.4 3 1 0 3 3 3 0 EF-hand domain pair KA1 PF02149.19 CDJ46901.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 Kinase associated domain 1 GPHH PF16905.5 CDJ46901.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated US22 PF02393.16 CDJ46902.1 - 0.089 13.1 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 US22 like DUF2500 PF10694.9 CDJ46902.1 - 0.12 12.9 0.0 0.47 11.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) 3HCDH_N PF02737.18 CDJ46903.1 - 4.1e-41 140.8 0.9 1.4e-40 139.1 0.9 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CDJ46903.1 - 2.9e-36 124.0 0.0 6.6e-36 122.8 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Methyltransf_25 PF13649.6 CDJ46903.1 - 0.079 13.7 0.0 0.19 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PTP_N PF12453.8 CDJ46903.1 - 0.29 10.9 1.0 27 4.6 0.0 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal Methyltransf_31 PF13847.6 CDJ46904.1 - 5.7e-11 42.4 2.2 3.2e-08 33.5 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ46904.1 - 1e-06 29.3 0.7 4.2e-06 27.4 0.0 2.4 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ46904.1 - 7.5e-06 26.5 0.0 5.6e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ46904.1 - 1.4e-05 25.0 0.0 5.1e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ46904.1 - 0.00028 21.6 0.7 0.00092 19.9 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_9 PF08003.11 CDJ46904.1 - 0.036 13.0 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.13 CDJ46904.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Macoilin PF09726.9 CDJ46904.1 - 0.54 8.8 8.6 0.011 14.4 1.9 1.6 2 0 0 2 2 2 0 Macoilin family Corona_nucleoca PF00937.18 CDJ46904.1 - 2.6 7.0 14.0 4.3 6.3 14.0 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RAP1 PF07218.11 CDJ46904.1 - 3.7 5.7 6.7 5 5.3 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SDP_N PF12278.8 CDJ46904.1 - 9.2 6.4 10.1 1.2 9.3 4.8 2.3 2 0 0 2 2 2 0 Sex determination protein N terminal AP2 PF00847.20 CDJ46905.1 - 3.8e-06 27.0 0.1 7.1e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 AP2 domain ALAD PF00490.21 CDJ46906.1 - 8.6e-123 409.5 0.1 1.6e-122 408.7 0.1 1.4 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Peptidase_M16_C PF05193.21 CDJ46906.1 - 1.3e-24 87.3 0.1 3.4e-13 50.0 0.1 3.8 2 2 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDJ46906.1 - 7.5e-17 61.7 0.8 7.1e-15 55.3 0.6 2.8 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) DNA_pol_phi PF04931.13 CDJ46906.1 - 1.1 7.2 12.7 2.1 6.4 12.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 CDJ46906.1 - 3.8 7.7 15.7 7.4 6.8 15.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 CDJ46906.1 - 4.9 5.2 6.1 8.2 4.5 6.1 1.2 1 0 0 1 1 1 0 Nop14-like family RT_RNaseH PF17917.1 CDJ46910.1 - 7.7e-24 84.0 0.0 1.5e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ46910.1 - 1.9e-23 82.4 0.0 3.8e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ46910.1 - 0.00052 19.6 0.2 0.012 15.2 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MNNL PF07657.13 CDJ46910.1 - 0.022 14.8 0.8 0.046 13.8 0.1 1.8 2 0 0 2 2 2 0 N terminus of Notch ligand Asp_protease_2 PF13650.6 CDJ46910.1 - 0.025 15.2 0.0 0.058 14.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 CDJ46910.1 - 0.057 14.0 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 CDJ46911.1 - 4.2e-16 58.8 1.0 4.2e-16 58.8 1.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CDJ46911.1 - 1.2e-13 51.3 0.0 4.7e-13 49.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 CDJ46911.1 - 1.4e-09 37.9 0.1 3.2e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CDJ46911.1 - 0.00054 20.1 0.4 0.0011 19.1 0.4 1.5 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDJ46911.1 - 0.0055 16.5 0.1 0.7 9.7 0.0 2.8 2 0 0 2 2 2 1 Integrase core domain Glt_symporter PF03616.14 CDJ46912.1 - 8.1e-06 24.8 3.7 8.5e-06 24.7 3.7 1.0 1 0 0 1 1 1 1 Sodium/glutamate symporter RskA PF10099.9 CDJ46912.1 - 0.00078 19.8 23.0 0.00096 19.5 23.0 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Shadoo PF14999.6 CDJ46912.1 - 0.0062 16.6 4.2 0.0063 16.6 4.2 1.2 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective PEX11 PF05648.14 CDJ46912.1 - 0.058 12.8 2.7 0.056 12.9 2.7 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) EphA2_TM PF14575.6 CDJ46912.1 - 0.15 13.0 1.8 0.19 12.6 1.8 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 CDJ46912.1 - 0.23 12.5 8.7 0.3 12.1 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) IHABP4_N PF16174.5 CDJ46912.1 - 0.81 10.3 15.8 0.85 10.2 15.8 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal FHIPEP PF00771.20 CDJ46912.1 - 1.3 7.4 10.3 1.3 7.4 10.3 1.0 1 0 0 1 1 1 0 FHIPEP family Presenilin PF01080.17 CDJ46912.1 - 1.7 7.4 8.3 1.5 7.5 8.3 1.1 1 0 0 1 1 1 0 Presenilin DUF2232 PF09991.9 CDJ46912.1 - 1.7 7.7 5.3 1.9 7.6 5.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Peptidase_S15 PF02129.18 CDJ46912.1 - 1.7 8.1 10.1 1.9 8.0 10.1 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Suf PF05843.14 CDJ46912.1 - 2.1 8.3 14.1 2.1 8.3 14.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CRF1 PF10380.9 CDJ46912.1 - 2.6 8.4 5.9 3.2 8.1 5.7 1.3 1 1 0 1 1 1 0 Transcription factor CRF1 R_equi_Vir PF05526.11 CDJ46912.1 - 4.9 7.0 9.8 5.3 6.9 9.8 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF4179 PF13786.6 CDJ46912.1 - 5.6 7.5 9.8 14 6.3 9.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) eIF3_subunit PF08597.10 CDJ46912.1 - 5.9 6.7 15.1 7 6.5 15.1 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit UPF0560 PF10577.9 CDJ46912.1 - 9.5 4.6 14.4 9.6 4.6 14.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DivIC PF04977.15 CDJ46912.1 - 9.5 6.1 19.7 0.72 9.7 15.1 1.7 2 0 0 2 2 2 0 Septum formation initiator LapA_dom PF06305.11 CDJ46912.1 - 9.6 6.1 13.7 46 3.9 13.7 2.2 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MutS_V PF00488.21 CDJ46914.1 - 6.4e-59 199.2 0.1 3.8e-58 196.6 0.1 2.1 1 1 0 1 1 1 1 MutS domain V MutS_I PF01624.20 CDJ46914.1 - 9.5e-25 87.0 0.0 2.4e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 CDJ46914.1 - 6e-17 62.5 0.5 6e-17 62.5 0.5 3.2 2 2 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CDJ46914.1 - 1.1e-07 32.1 0.8 2.4e-07 31.0 0.8 1.6 1 0 0 1 1 1 1 MutS family domain IV SUIM_assoc PF16619.5 CDJ46914.1 - 0.015 15.4 0.6 0.015 15.4 0.6 11.8 8 3 1 9 9 9 0 Unstructured region C-term to UIM in Ataxin3 ALS_ss_C PF10369.9 CDJ46914.1 - 0.036 14.3 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 Small subunit of acetolactate synthase AAA_29 PF13555.6 CDJ46914.1 - 0.14 11.9 0.4 0.34 10.7 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AMP-binding PF00501.28 CDJ46915.1 - 0.4 9.2 3.2 0.44 9.1 3.2 1.1 1 0 0 1 1 1 0 AMP-binding enzyme SID-1_RNA_chan PF13965.6 CDJ46915.1 - 0.43 8.9 1.8 0.44 8.9 1.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LMBR1 PF04791.16 CDJ46915.1 - 0.44 9.4 10.1 0.47 9.3 10.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RXLR PF16810.5 CDJ46915.1 - 0.48 10.8 7.2 0.69 10.3 7.2 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity BAF1_ABF1 PF04684.13 CDJ46915.1 - 0.55 9.2 14.1 0.64 9.0 14.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Consortin_C PF15281.6 CDJ46915.1 - 0.58 10.2 2.0 0.97 9.4 2.0 1.4 1 0 0 1 1 1 0 Consortin C-terminus Paramyxo_ncap PF00973.19 CDJ46915.1 - 0.84 8.5 10.9 1 8.2 10.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein MARCKS PF02063.17 CDJ46915.1 - 1.4 8.9 23.3 1.8 8.5 23.3 1.1 1 0 0 1 1 1 0 MARCKS family Hamartin PF04388.12 CDJ46915.1 - 1.6 7.3 15.3 1.9 7.0 15.3 1.0 1 0 0 1 1 1 0 Hamartin protein V_ATPase_I PF01496.19 CDJ46915.1 - 2.1 6.2 11.0 2.3 6.0 11.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S49_N PF08496.10 CDJ46915.1 - 2.1 8.4 13.5 0.09 12.8 7.8 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Serinc PF03348.15 CDJ46915.1 - 2.4 7.0 7.7 2.8 6.8 7.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SPX PF03105.19 CDJ46915.1 - 2.4 8.0 14.1 2.9 7.7 14.1 1.1 1 0 0 1 1 1 0 SPX domain SLC12 PF03522.15 CDJ46915.1 - 3 6.8 12.9 3.7 6.5 12.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ46915.1 - 3.2 6.4 19.6 3.9 6.1 19.6 1.1 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 CDJ46915.1 - 3.9 7.0 16.4 5.2 6.6 16.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.16 CDJ46915.1 - 7.6 6.5 13.5 10 6.1 13.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S64 PF08192.11 CDJ46915.1 - 8.1 4.8 10.5 9.2 4.6 10.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 ArsA_ATPase PF02374.15 CDJ46916.1 - 5.1e-35 121.1 4.8 2.6e-16 59.7 0.4 4.0 2 1 2 4 4 4 3 Anion-transporting ATPase CHZ PF09649.10 CDJ46916.1 - 0.13 11.7 3.8 23 4.6 0.1 3.2 1 1 2 3 3 3 0 Histone chaperone domain CHZ RCR PF12273.8 CDJ46917.1 - 0.00027 21.6 6.1 0.00073 20.2 6.1 1.8 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red PIP5K PF01504.18 CDJ46917.1 - 0.013 14.7 5.0 0.034 13.4 5.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SpoIIP PF07454.11 CDJ46917.1 - 0.039 13.4 9.2 0.087 12.3 9.2 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 CDJ46917.1 - 0.043 12.8 11.5 0.093 11.7 11.5 1.5 1 0 0 1 1 1 0 Solute carrier family 12 CLN3 PF02487.17 CDJ46917.1 - 0.076 12.1 7.5 0.18 10.8 7.5 1.7 1 0 0 1 1 1 0 CLN3 protein V_ATPase_I PF01496.19 CDJ46917.1 - 0.17 9.8 13.7 0.27 9.1 13.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neuraminidase PF18413.1 CDJ46917.1 - 0.24 11.0 7.1 0.64 9.7 7.1 1.7 1 0 0 1 1 1 0 Neuraminidase-like domain Baculo_PP31 PF05311.11 CDJ46917.1 - 0.42 10.1 7.2 1.2 8.6 7.2 1.7 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SID-1_RNA_chan PF13965.6 CDJ46917.1 - 0.43 8.9 2.4 0.75 8.1 2.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CSG2 PF16965.5 CDJ46917.1 - 0.54 9.2 6.8 0.18 10.7 3.5 1.8 2 0 0 2 2 2 0 Ceramide synthase regulator Connexin PF00029.19 CDJ46917.1 - 0.58 9.9 6.9 1.2 8.8 6.9 1.5 1 0 0 1 1 1 0 Connexin Hid1 PF12722.7 CDJ46917.1 - 0.72 7.9 21.3 1.7 6.7 0.3 2.4 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF2370 PF10176.9 CDJ46917.1 - 0.76 9.4 5.8 2 8.0 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Cellulose_synt PF03552.14 CDJ46917.1 - 1.5 7.3 5.3 2.2 6.7 5.3 1.1 1 0 0 1 1 1 0 Cellulose synthase CAF1 PF04857.20 CDJ46917.1 - 1.8 7.7 10.5 4.1 6.5 10.5 1.5 1 0 0 1 1 1 0 CAF1 family ribonuclease TCP PF03634.13 CDJ46917.1 - 3.5 8.2 32.8 0.13 12.8 10.1 4.4 4 0 0 4 4 4 0 TCP family transcription factor Ribosomal_60s PF00428.19 CDJ46920.1 - 0.00069 20.1 5.4 0.00069 20.1 5.4 8.0 7 2 0 7 7 7 2 60s Acidic ribosomal protein RskA PF10099.9 CDJ46920.1 - 0.0022 18.3 6.9 0.0022 18.3 6.9 6.6 2 2 3 5 5 5 2 Anti-sigma-K factor rskA LCD1 PF09798.9 CDJ46920.1 - 0.17 10.4 0.0 0.17 10.4 0.0 3.4 1 1 0 2 2 2 0 DNA damage checkpoint protein MARVEL PF01284.23 CDJ46921.1 - 0.48 10.4 14.3 0.83 9.7 14.3 1.4 1 1 0 1 1 1 0 Membrane-associating domain Tau95 PF09734.9 CDJ46923.1 - 1.6e-12 48.4 0.2 1.1e-10 42.4 0.1 4.5 3 1 1 4 4 4 2 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Spore_YhcN_YlaJ PF09580.10 CDJ46923.1 - 0.53 10.4 0.0 0.53 10.4 0.0 3.1 2 1 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) V_ATPase_I PF01496.19 CDJ46923.1 - 2 6.2 35.9 0.17 9.8 4.1 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Sporozoite_P67 PF05642.11 CDJ46923.1 - 5.9 4.9 40.1 0.27 9.3 31.1 2.4 2 1 0 2 2 2 0 Sporozoite P67 surface antigen GDI PF00996.18 CDJ46924.1 - 5.2e-12 45.0 0.0 3e-06 26.0 0.0 3.3 3 0 0 3 3 3 3 GDP dissociation inhibitor DUF2722 PF10846.8 CDJ46924.1 - 0.0028 16.7 0.0 0.0028 16.7 0.0 11.1 6 3 3 9 9 9 2 Protein of unknown function (DUF2722) Ank_2 PF12796.7 CDJ46926.1 - 2.6e-17 63.1 2.5 1.9e-13 50.8 0.3 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ46926.1 - 8.5e-16 58.1 1.3 5e-06 27.0 0.0 4.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ46926.1 - 1.9e-13 49.3 7.5 0.0006 20.1 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CDJ46926.1 - 1.5e-12 47.4 7.2 1.6e-08 34.7 0.5 4.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ46926.1 - 7.1e-12 45.2 15.1 9.5e-05 22.7 0.1 6.0 6 0 0 6 6 6 3 Ankyrin repeat SET PF00856.28 CDJ46926.1 - 0.00029 21.3 0.0 0.0041 17.5 0.0 2.9 2 1 1 3 3 3 1 SET domain gag-asp_proteas PF13975.6 CDJ46927.1 - 0.02 15.5 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ46927.1 - 0.06 14.0 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Hydin_ADK PF17213.3 CDJ46928.1 - 0.1 12.8 0.2 0.16 12.2 0.2 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA PF00004.29 CDJ46929.1 - 6.2e-39 133.4 0.0 2.1e-38 131.7 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CDJ46929.1 - 2.4e-19 69.0 0.1 4.7e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CDJ46929.1 - 9.3e-12 44.6 0.1 2.1e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ46929.1 - 6.3e-06 26.2 0.1 3.4e-05 23.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ46929.1 - 2.5e-05 24.6 0.0 6.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ46929.1 - 2.8e-05 24.6 0.5 0.003 17.9 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 CDJ46929.1 - 9.3e-05 22.6 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CDJ46929.1 - 0.003 17.7 0.0 0.0077 16.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDJ46929.1 - 0.0035 16.8 0.1 0.014 14.8 0.0 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CDJ46929.1 - 0.0053 16.1 0.2 0.11 11.8 0.0 2.4 2 0 0 2 2 2 1 KaiC RuvB_N PF05496.12 CDJ46929.1 - 0.013 15.2 0.0 0.043 13.6 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 CDJ46929.1 - 0.014 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 CDJ46929.1 - 0.015 15.0 0.0 0.042 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDJ46929.1 - 0.037 13.8 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CDJ46929.1 - 0.071 12.8 0.0 0.32 10.7 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain CENP-F_leu_zip PF10473.9 CDJ46929.1 - 0.08 13.0 2.1 0.36 10.9 1.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 CDJ46929.1 - 0.11 12.9 3.6 0.21 12.0 1.7 2.4 2 0 0 2 2 2 0 Cell division protein ZapB TIP49 PF06068.13 CDJ46929.1 - 0.12 11.5 0.8 0.91 8.7 0.0 2.1 1 1 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 CDJ46929.1 - 0.16 11.4 0.0 0.44 10.0 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Exo_endo_phos PF03372.23 CDJ46930.1 - 3.2e-11 43.2 0.0 1.4e-10 41.1 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2722 PF10846.8 CDJ46931.1 - 0.00041 19.4 4.9 0.00041 19.4 4.9 6.9 5 1 1 6 6 6 1 Protein of unknown function (DUF2722) Trp_oprn_chp PF09534.10 CDJ46931.1 - 0.004 17.0 1.5 0.004 17.0 1.5 5.9 2 2 3 5 5 5 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SARAF PF06682.12 CDJ46931.1 - 0.0041 16.8 10.1 0.0041 16.8 10.1 4.1 3 2 1 4 4 4 2 SOCE-associated regulatory factor of calcium homoeostasis DUF3824 PF12868.7 CDJ46931.1 - 0.0058 17.3 0.8 0.0058 17.3 0.8 10.2 5 3 4 9 9 9 1 Domain of unknwon function (DUF3824) PAP2 PF01569.21 CDJ46931.1 - 0.029 14.1 2.7 2.6 7.8 0.3 3.8 4 0 0 4 4 4 0 PAP2 superfamily DUF3678 PF12435.8 CDJ46931.1 - 1 8.8 9.2 1.1 8.8 4.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Utp14 PF04615.13 CDJ46931.1 - 1.8 7.0 42.7 0.088 11.4 28.6 2.3 2 0 0 2 2 2 0 Utp14 protein NPL PF17800.1 CDJ46932.1 - 0.005 17.4 0.0 0.005 17.4 0.0 3.2 2 1 0 2 2 2 1 Nucleoplasmin-like domain Drc1-Sld2 PF11719.8 CDJ46932.1 - 0.13 11.8 37.4 0.18 11.3 37.4 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Utp14 PF04615.13 CDJ46932.1 - 0.13 10.8 40.1 0.16 10.5 40.1 1.1 1 0 0 1 1 1 0 Utp14 protein DUF755 PF05501.11 CDJ46932.1 - 1.6 9.0 15.6 3.8 7.8 15.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Macoilin PF09726.9 CDJ46932.1 - 8.7 4.8 20.5 11 4.5 20.5 1.1 1 0 0 1 1 1 0 Macoilin family DUF726 PF05277.12 CDJ46933.1 - 0.033 13.1 0.3 0.048 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF454 PF04304.13 CDJ46933.1 - 0.11 12.5 0.8 1.7 8.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF454) C2 PF00168.30 CDJ46934.1 - 1.9e-10 41.0 0.0 2.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 C2 domain Memo PF01875.17 CDJ46938.1 - 4.7e-43 147.3 0.0 5.9e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Ca_hom_mod PF14798.6 CDJ46939.1 - 0.023 13.8 4.7 0.038 13.1 4.7 1.4 1 0 0 1 1 1 0 Calcium homeostasis modulator Spt20 PF12090.8 CDJ46939.1 - 0.24 11.0 35.3 0.65 9.6 3.9 2.3 2 0 0 2 2 2 0 Spt20 family GWT1 PF06423.12 CDJ46939.1 - 0.25 11.5 1.7 0.45 10.6 1.8 1.6 1 1 0 1 1 1 0 GWT1 ABC2_membrane_3 PF12698.7 CDJ46939.1 - 0.29 10.2 4.1 0.062 12.4 0.3 1.6 1 1 1 2 2 2 0 ABC-2 family transporter protein SAE2 PF08573.10 CDJ46939.1 - 0.41 11.8 7.9 4.8 8.3 0.2 2.2 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus SARAF PF06682.12 CDJ46939.1 - 0.63 9.6 16.5 1.7 8.2 7.4 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Vma12 PF11712.8 CDJ46939.1 - 1.1 9.4 6.9 1.4 9.0 0.4 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Med15 PF09606.10 CDJ46939.1 - 3.8 6.1 33.6 5 5.7 33.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CDJ46940.1 - 0.0065 15.5 1.6 0.007 15.4 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ46940.1 - 0.008 15.8 7.2 0.011 15.3 7.2 1.3 1 0 0 1 1 1 1 Spt20 family SUIM_assoc PF16619.5 CDJ46940.1 - 0.09 12.8 8.9 0.17 12.0 8.9 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SARAF PF06682.12 CDJ46940.1 - 0.11 12.2 4.0 0.12 12.0 4.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TFIIA PF03153.13 CDJ46940.1 - 0.61 10.0 19.5 1.3 9.0 19.4 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4366 PF14283.6 CDJ46940.1 - 0.99 9.4 5.9 0.37 10.8 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) AUX_IAA PF02309.16 CDJ46940.1 - 1.8 8.4 3.7 2.9 7.7 3.7 1.4 1 0 0 1 1 1 0 AUX/IAA family CYSTM PF12734.7 CDJ46940.1 - 4.3 7.7 12.4 10 6.5 12.4 1.6 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Ndc1_Nup PF09531.10 CDJ46940.1 - 6.5 5.3 7.7 8 5.0 7.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1980 PF09323.10 CDJ46941.1 - 0.12 12.2 0.1 0.12 12.2 0.1 13.7 9 4 1 11 11 11 0 Domain of unknown function (DUF1980) Hamartin PF04388.12 CDJ46942.1 - 0.025 13.3 17.2 0.011 14.4 8.8 2.3 2 0 0 2 2 2 0 Hamartin protein Velvet PF11754.8 CDJ46942.1 - 0.16 11.9 22.7 0.69 9.8 16.3 2.5 2 0 0 2 2 2 0 Velvet factor DUF740 PF05340.12 CDJ46942.1 - 0.19 10.4 5.4 0.41 9.3 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF2052 PF09747.9 CDJ46942.1 - 0.21 11.7 31.0 0.21 11.7 24.9 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF2956 PF11169.8 CDJ46943.1 - 0.025 14.8 12.4 0.025 14.8 12.4 2.7 2 1 1 3 3 1 0 Protein of unknown function (DUF2956) Exonuc_VII_L PF02601.15 CDJ46943.1 - 0.25 10.9 34.1 0.3 10.6 34.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPR3 PF03666.13 CDJ46943.1 - 0.38 9.5 25.7 0.49 9.1 25.7 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Caldesmon PF02029.15 CDJ46943.1 - 0.39 9.4 28.7 0.48 9.1 28.7 1.2 1 0 0 1 1 1 0 Caldesmon ALMT PF11744.8 CDJ46943.1 - 0.96 8.2 23.5 1.3 7.8 23.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter MCM_bind PF09739.9 CDJ46943.1 - 1.1 7.7 24.0 1.4 7.2 24.0 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PAT1 PF09770.9 CDJ46943.1 - 1.4 7.1 57.9 1.7 6.8 57.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 CDJ46943.1 - 2 7.3 33.5 2.6 7.0 33.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Raftlin PF15250.6 CDJ46943.1 - 2.3 6.9 23.8 2.9 6.5 23.8 1.3 1 0 0 1 1 1 0 Raftlin XRN_M PF17846.1 CDJ46943.1 - 3.4 6.5 20.1 4 6.3 20.1 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Hid1 PF12722.7 CDJ46943.1 - 4.3 5.3 29.8 4.7 5.2 29.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RIFIN PF02009.16 CDJ46943.1 - 4.8 7.0 22.0 6.2 6.6 22.0 1.1 1 0 0 1 1 1 0 Rifin Membralin PF09746.9 CDJ46943.1 - 7.7 5.4 19.9 11 4.9 19.9 1.2 1 0 0 1 1 1 0 Tumour-associated protein SRP-alpha_N PF04086.13 CDJ46943.1 - 8.7 6.2 26.8 13 5.6 26.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LAP1C PF05609.12 CDJ46943.1 - 8.8 5.3 34.1 11 5.0 34.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Asp-B-Hydro_N PF05279.11 CDJ46943.1 - 8.9 6.3 24.2 10 6.1 24.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDK5_activator PF03261.15 CDJ46943.1 - 9.6 5.6 30.7 11 5.4 30.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CTD_bind PF04818.13 CDJ46944.1 - 8.4e-13 48.9 0.0 3.6e-12 46.9 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Surp PF01805.20 CDJ46944.1 - 0.0049 16.8 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Surp module SARAF PF06682.12 CDJ46944.1 - 0.9 9.1 50.3 0.012 15.3 7.2 3.6 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4207 PF13904.6 CDJ46945.1 - 6.6e-08 32.6 2.3 6.6e-08 32.6 2.3 2.9 1 1 0 2 2 2 1 Domain of unknown function (DUF4207) LMBR1 PF04791.16 CDJ46945.1 - 1.8 7.4 17.9 1.9 7.3 17.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GTP_EFTU PF00009.27 CDJ46946.1 - 7.4e-31 107.2 0.2 1.4e-20 73.6 0.0 2.9 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CDJ46946.1 - 2.7e-28 99.0 9.3 2.7e-28 99.0 9.3 4.7 4 2 0 4 4 4 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus RskA PF10099.9 CDJ46946.1 - 1.4e-07 32.0 48.7 0.043 14.1 13.3 4.6 2 1 0 2 2 2 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ46946.1 - 0.0015 18.5 0.1 0.0015 18.5 0.1 5.8 3 2 3 6 6 6 2 Unstructured region C-term to UIM in Ataxin3 MMR_HSR1 PF01926.23 CDJ46946.1 - 0.076 13.1 0.0 4.7 7.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDJ46946.1 - 0.25 11.4 11.2 0.31 11.1 0.0 4.3 4 1 0 4 4 4 0 Dynamin family HD_assoc PF13286.6 CDJ46947.1 - 9 6.9 12.2 0.24 11.9 5.0 2.1 2 0 0 2 2 2 0 Phosphohydrolase-associated domain L6_membrane PF05805.12 CDJ46948.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 L6 membrane protein RrnaAD PF00398.20 CDJ46950.1 - 1.5e-18 66.8 0.2 3.1e-17 62.5 0.0 2.1 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase DUF2722 PF10846.8 CDJ46950.1 - 0.00014 20.9 15.4 0.0079 15.2 0.2 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF2722) Methyltransf_23 PF13489.6 CDJ46950.1 - 0.0012 18.7 0.3 0.0012 18.7 0.3 2.7 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ46950.1 - 0.0029 18.3 0.1 0.012 16.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 CDJ46950.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_11 PF08241.12 CDJ46950.1 - 0.045 14.4 0.1 0.21 12.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DUF4441 PF14536.6 CDJ46950.1 - 0.067 13.4 0.7 0.067 13.4 0.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4441) Methyltransf_12 PF08242.12 CDJ46950.1 - 0.25 12.1 4.0 0.53 11.1 0.0 2.8 3 1 0 3 3 3 0 Methyltransferase domain Senescence_reg PF04520.13 CDJ46950.1 - 0.46 11.3 5.0 12 6.7 0.3 2.3 2 0 0 2 2 2 0 Senescence regulator PseudoU_synth_2 PF00849.22 CDJ46951.1 - 7.5e-08 32.6 0.0 7.5e-08 32.6 0.0 5.1 4 2 0 4 4 4 1 RNA pseudouridylate synthase Dsh_C PF12316.8 CDJ46951.1 - 0.0052 17.2 10.1 0.0052 17.2 10.1 8.0 6 1 0 7 7 7 1 Segment polarity protein dishevelled (Dsh) C terminal SOBP PF15279.6 CDJ46951.1 - 0.012 16.2 14.0 0.012 16.2 14.0 5.5 4 1 0 5 5 5 0 Sine oculis-binding protein RR_TM4-6 PF06459.12 CDJ46951.1 - 0.15 11.9 99.1 0.71 9.7 6.0 5.3 5 0 0 5 5 5 0 Ryanodine Receptor TM 4-6 Exonuc_VII_L PF02601.15 CDJ46952.1 - 0.13 11.8 16.1 0.22 11.0 16.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.13 CDJ46952.1 - 0.75 9.7 47.9 1.5 8.7 47.9 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GET2 PF08690.10 CDJ46953.1 - 0.03 14.0 1.2 0.067 12.9 1.2 1.6 1 0 0 1 1 1 0 GET complex subunit GET2 SPX PF03105.19 CDJ46953.1 - 0.17 11.8 3.5 0.14 12.1 0.7 2.0 2 0 0 2 2 2 0 SPX domain CDC14 PF08045.11 CDJ46953.1 - 0.29 10.2 1.7 0.56 9.3 1.7 1.4 1 0 0 1 1 1 0 Cell division control protein 14, SIN component TMEM171 PF15471.6 CDJ46953.1 - 1.5 7.7 8.7 0.028 13.4 1.0 2.0 2 0 0 2 2 2 0 Transmembrane protein family 171 CNDH2_M PF16869.5 CDJ46953.1 - 7.1 7.3 8.9 3.5 8.3 0.3 3.1 3 0 0 3 3 3 0 PF16858 CLP_protease PF00574.23 CDJ46954.1 - 5e-14 52.6 1.0 4.7e-09 36.4 0.2 3.3 3 1 0 3 3 3 2 Clp protease BLM10_mid PF16507.5 CDJ46955.1 - 5.9e-12 45.0 0.1 1.8e-10 40.1 0.0 4.3 4 0 0 4 4 4 3 Proteasome-substrate-size regulator, mid region DUF2722 PF10846.8 CDJ46956.1 - 7e-05 22.0 13.7 0.00085 18.4 0.9 8.9 8 1 0 8 8 8 6 Protein of unknown function (DUF2722) DEAD PF00270.29 CDJ46957.1 - 3.5e-14 52.9 1.9 3.5e-14 52.9 1.9 4.1 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ46957.1 - 5.8e-07 29.8 0.0 5.8e-07 29.8 0.0 3.8 4 0 0 4 4 4 2 Helicase conserved C-terminal domain SR-25 PF10500.9 CDJ46958.1 - 0.0035 17.0 3.8 0.0082 15.8 3.8 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Med15 PF09606.10 CDJ46959.1 - 0.00087 18.1 40.5 0.00087 18.1 40.5 2.9 3 0 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal Adap_comp_sub PF00928.21 CDJ46959.1 - 0.007 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF3381 PF11861.8 CDJ46959.1 - 0.007 16.2 3.2 0.007 16.2 3.2 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3381) FACT-Spt16_Nlob PF14826.6 CDJ46960.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain WD40 PF00400.32 CDJ46961.1 - 2e-20 72.7 3.3 1.8e-08 34.9 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ46961.1 - 1.1e-08 35.2 0.0 0.0029 17.8 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ46961.1 - 1.3e-06 27.6 0.2 0.0089 15.0 0.0 2.5 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ46961.1 - 0.00018 20.3 0.0 0.12 10.9 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.12 CDJ46961.1 - 0.028 14.4 0.0 0.21 11.6 0.0 2.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Connexin PF00029.19 CDJ46962.1 - 0.0032 17.3 7.1 0.013 15.3 7.1 2.0 1 0 0 1 1 1 1 Connexin SpoIIP PF07454.11 CDJ46962.1 - 0.0038 16.7 6.5 0.0038 16.7 6.5 2.3 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 CDJ46962.1 - 0.0076 16.5 8.7 0.0076 16.5 8.7 4.5 3 1 1 4 4 4 1 Cleavage and polyadenylation factor 2 C-terminal LPP PF04728.13 CDJ46962.1 - 0.012 16.0 6.2 0.012 16.0 6.2 7.9 9 1 0 9 9 9 0 Lipoprotein leucine-zipper ABC2_membrane_2 PF12679.7 CDJ46962.1 - 0.13 11.6 2.3 0.54 9.5 2.3 2.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4746 PF15928.5 CDJ46962.1 - 1.1 8.7 8.5 3.7 6.9 8.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CLN3 PF02487.17 CDJ46962.1 - 1.4 7.9 18.5 0.34 9.9 10.1 2.7 2 0 0 2 2 2 0 CLN3 protein Saw1 PF11561.8 CDJ46962.1 - 2 7.9 12.9 8.6 5.8 12.9 2.0 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Cu2_monoox_C PF03712.15 CDJ46963.1 - 0.048 13.2 1.9 0.054 13.0 1.9 1.1 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Spt20 PF12090.8 CDJ46963.1 - 1.4 8.5 15.6 1.5 8.3 15.6 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ46963.1 - 4.7 7.1 16.2 4.5 7.2 16.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CNDH2_M PF16869.5 CDJ46964.1 - 0.09 13.5 0.3 0.09 13.5 0.3 10.0 3 1 3 6 6 6 0 PF16858 Spt20 PF12090.8 CDJ46965.1 - 0.015 15.0 6.3 0.015 15.0 6.3 3.6 2 1 1 3 3 3 0 Spt20 family RCR PF12273.8 CDJ46965.1 - 0.13 13.0 13.6 2 9.1 9.4 2.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red RskA PF10099.9 CDJ46965.1 - 0.47 10.7 0.0 0.47 10.7 0.0 4.7 2 1 2 4 4 4 0 Anti-sigma-K factor rskA SARAF PF06682.12 CDJ46965.1 - 5.4 6.6 24.7 1.3 8.6 12.7 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1635 PF07795.11 CDJ46966.1 - 7 6.4 9.3 12 5.7 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) zf-RING_UBOX PF13445.6 CDJ46967.1 - 1.9e-06 27.7 7.3 1.9e-06 27.7 7.3 2.3 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ46967.1 - 9.2e-06 25.5 4.6 9.2e-06 25.5 4.6 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ46967.1 - 0.0003 20.6 5.6 0.0003 20.6 5.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ46967.1 - 0.00097 19.4 8.4 0.00097 19.4 8.4 2.3 2 0 0 2 2 2 1 Ring finger domain RskA PF10099.9 CDJ46967.1 - 0.0018 18.6 22.9 0.033 14.5 4.4 2.6 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ46967.1 - 0.002 17.8 10.0 0.002 17.8 10.0 2.3 2 0 0 2 2 2 1 Spt20 family Suf PF05843.14 CDJ46967.1 - 0.01 15.8 10.3 0.042 13.8 1.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Tau95_N PF17682.1 CDJ46967.1 - 0.02 15.1 2.8 2 8.6 0.1 2.3 2 0 0 2 2 2 0 Tau95 Triple barrel domain Baculo_PP31 PF05311.11 CDJ46967.1 - 0.021 14.3 8.5 0.42 10.1 4.2 2.3 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) zf-C3HC4_4 PF15227.6 CDJ46967.1 - 0.021 15.0 9.1 0.021 15.0 9.1 3.1 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Thg1C PF14413.6 CDJ46967.1 - 0.035 14.3 6.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Thg1 C terminal domain EOS1 PF12326.8 CDJ46967.1 - 0.077 12.9 4.3 2.2 8.2 1.0 2.1 2 0 0 2 2 2 0 N-glycosylation protein DUF4834 PF16118.5 CDJ46967.1 - 0.082 13.9 0.6 0.082 13.9 0.6 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) BRF1 PF07741.13 CDJ46967.1 - 0.1 13.0 16.1 1.4 9.3 1.0 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF2052 PF09747.9 CDJ46967.1 - 0.12 12.5 13.6 0.23 11.6 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Pro_CA PF00484.19 CDJ46967.1 - 0.24 11.7 5.6 0.27 11.5 0.2 2.3 2 0 0 2 2 2 0 Carbonic anhydrase zf-C3HC4_3 PF13920.6 CDJ46967.1 - 0.39 10.6 16.0 0.044 13.6 6.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) U79_P34 PF03064.16 CDJ46967.1 - 0.4 10.0 8.3 0.094 12.1 1.8 2.1 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Connexin PF00029.19 CDJ46967.1 - 0.45 10.2 5.4 2.1 8.0 0.9 2.2 2 0 0 2 2 2 0 Connexin Peroxin-13_N PF04088.13 CDJ46967.1 - 0.8 10.0 6.7 4.7 7.5 0.7 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Rtf2 PF04641.12 CDJ46967.1 - 1.2 8.4 19.6 0.41 10.0 6.0 2.6 1 1 1 2 2 2 0 Rtf2 RING-finger EPL1 PF10513.9 CDJ46967.1 - 2.1 8.7 14.6 2.4 8.5 1.8 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like cwf18 PF08315.12 CDJ46967.1 - 2.5 8.8 21.2 0.49 11.1 3.7 2.4 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor DUF2722 PF10846.8 CDJ46967.1 - 3.4 6.5 36.3 0.011 14.7 8.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) EIIBC-GUT_N PF03612.14 CDJ46967.1 - 4.4 7.0 12.6 4.6 6.9 3.8 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus FTZ PF03867.14 CDJ46967.1 - 6.5 6.2 15.5 1.2 8.6 7.0 2.3 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region Nitroreductase PF00881.24 CDJ46967.1 - 7.3 6.6 14.9 1.5 8.8 6.1 2.2 2 0 0 2 2 2 0 Nitroreductase family PEX11 PF05648.14 CDJ46967.1 - 8.7 5.7 10.6 1.7 8.0 0.2 2.2 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) TERB2 PF15101.6 CDJ46967.1 - 8.8 6.3 19.9 2.5 8.1 3.9 2.5 3 0 0 3 3 2 0 Telomere-associated protein TERB2 DUF5427 PF10310.9 CDJ46967.1 - 9.1 5.1 23.8 0.077 11.9 7.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5427) RskA PF10099.9 CDJ46969.1 - 0.0011 19.4 0.7 0.0011 19.4 0.7 11.4 2 2 6 9 9 9 1 Anti-sigma-K factor rskA BRCT PF00533.26 CDJ46970.1 - 3e-09 37.1 0.0 7e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Pex14_N PF04695.13 CDJ46971.1 - 0.33 11.6 29.3 0.65 10.7 4.8 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2391 PF09622.10 CDJ46971.1 - 7.2 5.9 11.0 1.7 7.9 3.6 2.3 2 1 0 2 2 2 0 Putative integral membrane protein (DUF2391) GTP1_OBG PF01018.22 CDJ46972.1 - 1.8e-20 73.1 1.1 1.8e-20 73.1 1.1 2.0 2 1 0 2 2 2 1 GTP1/OBG MMR_HSR1 PF01926.23 CDJ46972.1 - 4.3e-06 26.8 0.1 2.3e-05 24.4 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase SLC12 PF03522.15 CDJ46972.1 - 0.4 9.6 28.6 0.61 9.1 28.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ46972.1 - 1.1 9.1 34.5 1.6 8.5 34.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dynamin_N PF00350.23 CDJ46972.1 - 2 8.4 21.5 1e+02 2.9 21.5 2.3 1 1 0 1 1 1 0 Dynamin family Presenilin PF01080.17 CDJ46972.1 - 3.7 6.2 34.0 7.1 5.3 34.0 1.5 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 CDJ46972.1 - 4.3 6.0 24.1 7.4 5.2 24.1 1.3 1 0 0 1 1 1 0 Raftlin Aminotran_5 PF00266.19 CDJ46973.1 - 0.01 14.8 0.0 0.022 13.7 0.0 1.5 1 1 1 2 2 2 0 Aminotransferase class-V Apt1 PF10351.9 CDJ46973.1 - 0.075 11.9 15.2 0.011 14.6 2.7 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain CAP_N PF01213.19 CDJ46973.1 - 1.7 8.0 18.6 0.43 10.0 8.1 2.9 2 1 1 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Presenilin PF01080.17 CDJ46973.1 - 2.6 6.7 13.6 1.4 7.6 3.9 2.0 2 0 0 2 2 2 0 Presenilin Spt20 PF12090.8 CDJ46973.1 - 8.4 5.9 24.1 0.11 12.1 15.4 1.9 2 0 0 2 2 2 0 Spt20 family Pkinase_fungal PF17667.1 CDJ46973.1 - 9.8 4.8 10.1 0.45 9.2 0.4 2.0 2 0 0 2 2 2 0 Fungal protein kinase Peptidase_S49_N PF08496.10 CDJ46974.1 - 0.00011 22.3 9.6 0.00011 22.3 9.6 6.4 6 0 0 6 6 6 3 Peptidase family S49 N-terminal CLN3 PF02487.17 CDJ46974.1 - 0.0042 16.2 8.0 0.0042 16.2 8.0 5.6 5 1 0 5 5 5 2 CLN3 protein RskA PF10099.9 CDJ46974.1 - 0.0049 17.2 11.4 0.0049 17.2 11.4 9.8 4 3 3 7 7 7 2 Anti-sigma-K factor rskA Chorion_2 PF03964.15 CDJ46974.1 - 0.008 17.0 1.1 0.008 17.0 1.1 12.2 6 3 5 11 11 11 1 Chorion family 2 Afi1 PF07792.12 CDJ46974.1 - 0.012 16.1 9.5 0.012 16.1 9.5 6.3 6 1 0 6 6 6 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NICE-1 PF15845.5 CDJ46974.1 - 0.022 15.5 10.1 0.022 15.5 10.1 10.9 6 5 4 10 10 10 0 Cysteine-rich C-terminal 1 family BUD22 PF09073.10 CDJ46974.1 - 0.098 12.0 0.1 0.019 14.3 14.6 5.6 5 1 1 6 6 6 0 BUD22 Saw1 PF11561.8 CDJ46974.1 - 3.7 7.0 0.0 3.7 7.0 0.0 5.0 5 1 0 5 5 5 0 Single strand annealing-weakened 1 SURF6 PF04935.12 CDJ46974.1 - 5.5 6.7 91.6 1.1 9.0 5.7 6.1 6 0 0 6 6 6 0 Surfeit locus protein 6 CAP_GLY PF01302.25 CDJ46976.1 - 1.6e-11 44.0 1.4 2.2e-11 43.6 1.4 1.2 1 0 0 1 1 1 1 CAP-Gly domain IQ PF00612.27 CDJ46976.1 - 0.019 14.7 0.7 0.019 14.7 0.7 1.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif SelR PF01641.18 CDJ46976.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.4 1 1 0 1 1 1 0 SelR domain Chromo PF00385.24 CDJ46979.1 - 1.1e-09 38.0 0.0 3.7e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CDJ46979.1 - 0.065 13.4 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain HSP20 PF00011.21 CDJ46981.1 - 1.3e-19 70.2 0.0 2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ46981.1 - 3.9e-05 23.1 0.0 6.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Sel1 PF08238.12 CDJ46982.1 - 2.1e-30 104.4 20.4 0.00021 21.8 0.0 10.7 10 0 0 10 10 10 8 Sel1 repeat SID-1_RNA_chan PF13965.6 CDJ46982.1 - 0.29 9.5 1.5 0.31 9.4 0.2 1.6 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 RskA PF10099.9 CDJ46984.1 - 0.0059 16.9 6.8 0.0059 16.9 6.8 13.7 5 3 4 9 9 9 2 Anti-sigma-K factor rskA AAA_16 PF13191.6 CDJ46985.1 - 0.0014 19.0 6.2 0.0014 19.0 6.2 4.7 4 2 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 CDJ46985.1 - 0.0046 16.7 0.2 0.013 15.3 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 CDJ46985.1 - 0.014 15.6 0.1 0.014 15.6 0.1 3.4 3 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 CDJ46985.1 - 0.067 13.7 0.6 0.17 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain RskA PF10099.9 CDJ46986.1 - 4.8e-05 23.7 0.0 9.6e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Anti-sigma-K factor rskA Ribosomal_L12_N PF16320.5 CDJ46986.1 - 3.9 7.2 9.0 5.4 6.8 9.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain Sin3_corepress PF08295.12 CDJ46987.1 - 0.0029 17.6 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Sin3 family co-repressor Filament_head PF04732.14 CDJ46987.1 - 0.011 16.6 11.6 0.94 10.4 14.1 2.1 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region SR-25 PF10500.9 CDJ46987.1 - 0.095 12.3 11.4 0.13 11.9 11.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pollen_allerg_1 PF01357.21 CDJ46987.1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Pollen allergen Herpes_pp85 PF04637.12 CDJ46987.1 - 1.1 7.6 3.8 1.5 7.2 3.8 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Secretin_N_2 PF07655.13 CDJ46987.1 - 2.6 8.7 13.5 3.8 8.1 13.5 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain RAP1 PF07218.11 CDJ46987.1 - 6.6 4.9 7.4 8.2 4.6 7.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4603 PF15376.6 CDJ46988.1 - 0.31 8.4 19.3 0.34 8.3 19.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) SR-25 PF10500.9 CDJ46988.1 - 0.75 9.4 41.5 0.024 14.3 11.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ46988.1 - 1.6 8.9 11.2 2.7 8.1 11.1 1.3 1 1 0 1 1 1 0 Centriole, cilia and spindle-associated MMU163 PF17119.5 CDJ46988.1 - 3.2 6.9 4.8 0.4 9.8 0.4 1.6 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis SPX PF03105.19 CDJ46988.1 - 7.5 6.4 14.6 11 5.8 14.6 1.3 1 0 0 1 1 1 0 SPX domain Exonuc_VII_L PF02601.15 CDJ46989.1 - 0.0037 16.9 21.4 0.0056 16.3 21.4 1.5 1 0 0 1 1 1 1 Exonuclease VII, large subunit RskA PF10099.9 CDJ46989.1 - 0.0043 17.4 0.1 1.7 8.9 0.0 2.2 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Hamartin PF04388.12 CDJ46989.1 - 0.96 8.0 49.5 1.7 7.2 49.5 1.3 1 0 0 1 1 1 0 Hamartin protein CHZ PF09649.10 CDJ46991.1 - 0.09 12.3 0.1 0.51 9.9 0.1 2.4 1 0 0 1 1 1 0 Histone chaperone domain CHZ NicO PF03824.16 CDJ46991.1 - 8.3 5.7 10.1 56 2.9 10.1 2.6 1 0 0 1 1 1 0 High-affinity nickel-transport protein SPX PF03105.19 CDJ46992.1 - 0.017 15.1 13.5 0.023 14.6 13.5 1.1 1 0 0 1 1 1 0 SPX domain SelP_N PF04592.14 CDJ46992.1 - 0.12 11.7 11.8 0.23 10.8 11.8 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PBP_sp32 PF07222.12 CDJ46992.1 - 0.15 11.5 11.0 0.29 10.5 11.0 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SLC12 PF03522.15 CDJ46992.1 - 0.17 10.9 8.1 0.25 10.3 8.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Apt1 PF10351.9 CDJ46992.1 - 0.19 10.5 8.3 0.32 9.8 8.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 CDJ46992.1 - 0.48 8.6 8.0 0.67 8.2 8.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NST1 PF13945.6 CDJ46992.1 - 0.55 10.3 17.1 2.5 8.2 9.7 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator Eapp_C PF10238.9 CDJ46992.1 - 0.93 9.6 9.6 5.2 7.1 8.1 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein SET PF00856.28 CDJ46992.1 - 1.3 9.4 6.0 9.2 6.6 6.1 2.1 1 1 0 1 1 1 0 SET domain Spt20 PF12090.8 CDJ46992.1 - 1.9 8.0 33.1 0.59 9.7 24.8 2.1 2 0 0 2 2 2 0 Spt20 family YABBY PF04690.13 CDJ46992.1 - 4.6 7.8 8.6 1.4 9.5 3.6 2.0 2 0 0 2 2 2 0 YABBY protein Folliculin PF11704.8 CDJ46992.1 - 5.1 6.9 12.0 56 3.5 0.0 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Miga PF10265.9 CDJ46992.1 - 6.2 5.7 15.8 4.8 6.0 4.1 2.0 2 0 0 2 2 2 0 Mitoguardin Draxin PF15550.6 CDJ46992.1 - 6.7 6.5 14.8 9.6 6.0 14.8 1.1 1 0 0 1 1 1 0 Draxin PAM2 PF07145.15 CDJ46993.1 - 0.086 12.6 0.6 0.17 11.6 0.6 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Spt20 PF12090.8 CDJ46994.1 - 0.0013 18.3 7.4 0.0013 18.3 7.4 4.9 3 1 1 4 4 4 1 Spt20 family SARAF PF06682.12 CDJ46994.1 - 0.021 14.5 0.0 0.021 14.5 0.0 4.0 1 1 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Mpv17_PMP22 PF04117.12 CDJ46994.1 - 0.076 13.2 0.1 0.076 13.2 0.1 1.9 2 0 0 2 2 2 0 Mpv17 / PMP22 family Lin-8 PF03353.15 CDJ46994.1 - 0.3 10.6 36.1 0.17 11.5 2.2 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 CDJ46994.1 - 1 8.3 23.0 3.9 6.4 15.7 2.3 2 0 0 2 2 2 0 Solute carrier family 12 Dpy19 PF10034.9 CDJ46994.1 - 5.2 5.1 13.9 15 3.7 10.4 2.5 1 1 1 2 2 2 0 Q-cell neuroblast polarisation SID-1_RNA_chan PF13965.6 CDJ46994.1 - 9.6 4.5 9.5 1.5 7.1 2.6 2.5 2 1 1 3 3 3 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 CDJ46995.1 - 0.03 15.3 0.6 0.03 15.3 0.6 8.5 7 2 1 8 8 8 0 Domain of unknown function (DUF4834) zf-A20 PF01754.16 CDJ46996.1 - 1.4e-11 44.1 7.3 3.3e-11 42.9 7.3 1.7 1 0 0 1 1 1 1 A20-like zinc finger RAP1 PF07218.11 CDJ46997.1 - 1.3 7.3 11.1 1.9 6.6 11.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TFIID_30kDa PF03540.13 CDJ46998.1 - 3.8e-06 26.8 0.1 6.4e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit eIF2_C PF09173.11 CDJ46998.1 - 0.088 13.1 0.0 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Initiation factor eIF2 gamma, C terminal Prefoldin PF02996.17 CDJ46999.1 - 1.1e-17 64.0 5.0 1.5e-17 63.6 5.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit eIF-4B PF06273.11 CDJ46999.1 - 0.013 14.6 0.3 0.018 14.2 0.3 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B TMPIT PF07851.13 CDJ46999.1 - 0.41 9.8 6.4 0.87 8.8 0.1 2.0 2 0 0 2 2 2 0 TMPIT-like protein Nsp1_C PF05064.13 CDJ46999.1 - 1.4 8.7 7.7 0.23 11.3 1.6 2.4 2 1 0 2 2 2 0 Nsp1-like C-terminal region COG2 PF06148.11 CDJ46999.1 - 3.6 7.7 8.4 0.82 9.8 2.6 2.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 14-3-3 PF00244.20 CDJ47003.1 - 2.5e-98 328.0 8.0 2.9e-98 327.8 8.0 1.1 1 0 0 1 1 1 1 14-3-3 protein MKT1_N PF12247.8 CDJ47003.1 - 0.052 13.9 1.2 0.15 12.5 0.0 2.4 3 1 0 3 3 3 0 Temperature dependent protein affecting M2 dsRNA replication EGF_CA PF07645.15 CDJ47004.1 - 1.6e-27 95.4 71.3 1.1e-10 41.5 8.0 5.6 5 1 0 5 5 5 5 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ47004.1 - 4.7e-14 52.3 60.0 3.9e-05 23.8 0.8 6.1 5 1 1 6 6 6 5 EGF domain cEGF PF12662.7 CDJ47004.1 - 9.6e-09 35.0 38.6 9.6e-05 22.2 0.2 6.5 5 2 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.27 CDJ47004.1 - 2.1e-05 24.7 66.8 0.0065 16.7 8.1 7.0 7 1 0 7 7 7 5 EGF-like domain FXa_inhibition PF14670.6 CDJ47004.1 - 0.00047 20.4 61.1 0.025 14.8 2.4 6.0 5 1 1 6 6 6 4 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CDJ47004.1 - 0.0088 16.1 18.6 0.013 15.5 7.1 5.3 4 2 1 5 5 5 2 MSP1 EGF domain 1 hEGF PF12661.7 CDJ47004.1 - 0.028 15.0 6.0 0.028 15.0 6.0 7.8 7 1 0 7 7 7 0 Human growth factor-like EGF ORC3_N PF07034.11 CDJ47005.1 - 5.4e-10 38.9 3.8 5.4e-10 38.9 3.8 4.8 5 1 0 5 5 5 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 CDJ47005.1 - 0.00016 21.7 0.4 0.00016 21.7 0.4 6.4 5 2 0 5 5 5 1 Origin recognition complex winged helix C-terminal Pkinase PF00069.25 CDJ47007.1 - 1.7e-44 152.2 0.0 7.9e-24 84.4 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ47007.1 - 4.5e-27 95.0 0.0 2e-18 66.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ47007.1 - 0.00074 18.9 0.0 0.0035 16.7 0.0 2.1 1 1 0 1 1 1 1 Kinase-like SMYLE_N PF18615.1 CDJ47007.1 - 2 7.9 5.5 3.1 7.3 5.5 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Auxin_canalis PF05703.11 CDJ47008.1 - 0.0018 18.2 7.5 0.0018 18.2 7.5 2.0 2 0 0 2 2 2 1 Auxin canalisation DUF1180 PF06679.12 CDJ47008.1 - 3.7 8.0 14.9 22 5.4 4.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) PAN_1 PF00024.26 CDJ47009.1 - 3.1e-05 23.8 0.1 7e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 CDJ47009.1 - 0.0044 16.9 0.5 0.01 15.7 0.5 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 CDJ47009.1 - 0.035 14.2 0.6 0.095 12.8 0.6 1.7 1 0 0 1 1 1 0 PAN-like domain Glyco_hydro_16 PF00722.21 CDJ47010.1 - 0.00057 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SAE2 PF08573.10 CDJ47011.1 - 3.1e-07 31.5 0.9 3.1e-07 31.5 0.9 7.4 5 1 1 6 6 6 1 DNA repair protein endonuclease SAE2/CtIP C-terminus TFIIA PF03153.13 CDJ47012.1 - 0.012 15.7 39.6 0.016 15.2 39.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ47012.1 - 0.031 12.6 26.5 0.032 12.5 26.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ47012.1 - 0.094 12.5 15.5 0.11 12.4 15.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ47012.1 - 0.19 10.7 7.2 0.22 10.5 7.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 CDJ47012.1 - 0.24 11.1 8.6 0.34 10.6 8.6 1.4 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 CDJ47012.1 - 0.38 9.1 4.3 0.38 9.1 4.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SprA-related PF12118.8 CDJ47012.1 - 0.39 9.8 28.6 0.53 9.4 28.6 1.2 1 0 0 1 1 1 0 SprA-related family SLC12 PF03522.15 CDJ47012.1 - 0.49 9.4 14.7 0.53 9.2 14.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 eIF-3_zeta PF05091.12 CDJ47012.1 - 0.49 9.3 19.5 0.56 9.1 19.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tim54 PF11711.8 CDJ47012.1 - 0.65 8.7 12.9 0.89 8.3 12.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AAA_23 PF13476.6 CDJ47012.1 - 0.91 10.0 14.0 1.1 9.7 14.0 1.2 1 0 0 1 1 1 0 AAA domain CLN3 PF02487.17 CDJ47012.1 - 1.1 8.3 12.9 1.5 7.8 12.9 1.1 1 0 0 1 1 1 0 CLN3 protein DUF2828 PF11443.8 CDJ47012.1 - 1.6 6.7 14.9 2 6.4 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Paf1 PF03985.13 CDJ47012.1 - 3 6.7 18.9 3.4 6.6 18.9 1.2 1 0 0 1 1 1 0 Paf1 Exonuc_VII_L PF02601.15 CDJ47012.1 - 5.5 6.5 18.9 6.4 6.3 18.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HCO3_cotransp PF00955.21 CDJ47012.1 - 5.7 5.7 5.7 7.1 5.3 5.7 1.1 1 0 0 1 1 1 0 HCO3- transporter family CSG2 PF16965.5 CDJ47012.1 - 8.2 5.3 8.7 11 4.8 8.7 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Serinc PF03348.15 CDJ47012.1 - 8.2 5.2 8.1 10 5.0 8.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) AP2 PF00847.20 CDJ47013.1 - 1.1e-11 44.8 0.2 7.4e-11 42.1 0.2 2.5 1 0 0 1 1 1 1 AP2 domain MtN3_slv PF03083.16 CDJ47014.1 - 2.3e-31 107.7 5.9 1.4e-17 63.5 0.8 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF2722 PF10846.8 CDJ47014.1 - 3e-07 29.8 34.9 8.7e-05 21.7 15.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ47014.1 - 0.00039 20.5 76.9 0.0026 17.9 35.9 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ47014.1 - 0.00079 19.2 9.4 0.0045 16.8 0.3 2.3 2 0 0 2 2 2 1 Connexin DUF4834 PF16118.5 CDJ47014.1 - 0.0012 19.7 22.8 0.0014 19.6 5.7 3.0 3 0 0 3 3 2 1 Domain of unknown function (DUF4834) FAM91_C PF14648.6 CDJ47014.1 - 0.002 17.1 6.9 0.0027 16.6 0.7 2.1 2 0 0 2 2 2 1 FAM91 C-terminus Eapp_C PF10238.9 CDJ47014.1 - 0.0035 17.4 1.8 0.0035 17.4 1.8 3.0 2 1 0 2 2 1 1 E2F-associated phosphoprotein LAB_N PF07578.11 CDJ47014.1 - 0.0038 17.3 0.5 0.97 9.6 0.1 2.4 2 0 0 2 2 2 1 Lipid A Biosynthesis N-terminal domain OATP PF03137.20 CDJ47014.1 - 0.0042 15.4 9.0 0.035 12.4 0.2 2.9 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF3464 PF11947.8 CDJ47014.1 - 0.0045 16.7 23.8 0.098 12.4 5.1 3.9 3 0 0 3 3 3 1 Photosynthesis affected mutant 68 Ufd2P_core PF10408.9 CDJ47014.1 - 0.0048 15.6 0.3 0.0048 15.6 0.3 2.1 2 0 0 2 2 1 1 Ubiquitin elongating factor core RNase_H2_suC PF08615.11 CDJ47014.1 - 0.015 15.5 3.9 0.53 10.5 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Orf78 PF06024.12 CDJ47014.1 - 0.016 15.5 2.5 0.016 15.5 2.5 2.9 3 0 0 3 3 2 0 Orf78 (ac78) Velvet PF11754.8 CDJ47014.1 - 0.017 15.0 2.1 0.017 15.0 2.1 2.6 2 1 0 2 2 1 0 Velvet factor CLN3 PF02487.17 CDJ47014.1 - 0.019 14.0 0.2 0.019 14.0 0.2 2.6 3 0 0 3 3 2 0 CLN3 protein CDC45 PF02724.14 CDJ47014.1 - 0.021 13.2 0.4 0.021 13.2 0.4 3.0 2 1 1 3 3 1 0 CDC45-like protein CPSF100_C PF13299.6 CDJ47014.1 - 0.021 15.0 1.7 0.021 15.0 1.7 3.3 2 1 1 3 3 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF1980 PF09323.10 CDJ47014.1 - 0.032 14.1 10.8 0.074 13.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) RNA_pol_Rpc4 PF05132.14 CDJ47014.1 - 0.032 14.6 0.1 0.032 14.6 0.1 4.0 3 1 0 4 4 3 0 RNA polymerase III RPC4 FAM60A PF15396.6 CDJ47014.1 - 0.032 14.2 0.4 0.032 14.2 0.4 2.5 2 1 0 2 2 1 0 Protein Family FAM60A DAG_kinase_N PF14513.6 CDJ47014.1 - 0.034 14.4 0.3 0.034 14.4 0.3 2.8 2 1 1 3 3 2 0 Diacylglycerol kinase N-terminus SID-1_RNA_chan PF13965.6 CDJ47014.1 - 0.036 12.5 3.2 0.25 9.7 0.1 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF3405 PF11885.8 CDJ47014.1 - 0.04 12.5 0.1 0.04 12.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3405) CSG2 PF16965.5 CDJ47014.1 - 0.046 12.7 0.2 0.046 12.7 0.2 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator Peroxin-13_N PF04088.13 CDJ47014.1 - 0.046 14.0 0.2 0.046 14.0 0.2 2.7 3 0 0 3 3 2 0 Peroxin 13, N-terminal region Endostatin PF06482.11 CDJ47014.1 - 0.097 12.1 17.5 0.82 9.1 5.8 2.5 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Kei1 PF08552.11 CDJ47014.1 - 0.12 12.2 0.2 0.12 12.2 0.2 4.2 2 1 0 3 3 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3402 PF11882.8 CDJ47014.1 - 0.26 10.3 18.7 0.057 12.5 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) DUF913 PF06025.12 CDJ47014.1 - 0.32 9.9 0.0 0.32 9.9 0.0 3.1 2 1 1 3 3 2 0 Domain of Unknown Function (DUF913) Band_3_cyto PF07565.13 CDJ47014.1 - 0.43 10.3 18.0 0.91 9.3 6.5 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Anoctamin PF04547.12 CDJ47014.1 - 0.54 9.0 3.2 1.2 7.9 0.1 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel O-antigen_lig PF13425.6 CDJ47014.1 - 0.65 8.7 1.3 8.9 5.0 0.1 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein TT_ORF1 PF02956.14 CDJ47014.1 - 0.67 8.6 7.4 0.6 8.7 1.2 2.0 2 0 0 2 2 2 0 TT viral orf 1 V_ATPase_I PF01496.19 CDJ47014.1 - 0.82 7.5 20.9 0.014 13.3 3.8 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Consortin_C PF15281.6 CDJ47014.1 - 0.91 9.5 6.8 0.086 12.8 0.4 2.2 2 0 0 2 2 2 0 Consortin C-terminus LAP1C PF05609.12 CDJ47014.1 - 1.1 8.2 26.0 0.34 10.0 5.6 2.3 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) RICTOR_N PF14664.6 CDJ47014.1 - 1.2 8.0 7.4 0.19 10.7 0.5 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term DUF4770 PF15994.5 CDJ47014.1 - 1.3 9.3 24.5 0.085 13.1 6.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF4407 PF14362.6 CDJ47014.1 - 1.3 8.3 48.4 0.47 9.7 27.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2464 PF10240.9 CDJ47014.1 - 1.3 8.5 9.5 0.49 9.9 0.3 2.2 2 0 0 2 2 2 0 Multivesicular body subunit 12 DUF4228 PF14009.6 CDJ47014.1 - 1.5 9.2 0.0 1.5 9.2 0.0 3.8 2 1 0 2 2 1 0 Domain of unknown function (DUF4228) AAR2 PF05282.11 CDJ47014.1 - 1.5 8.1 9.3 0.55 9.6 0.8 2.2 2 0 0 2 2 2 0 AAR2 protein Scs3p PF10261.9 CDJ47014.1 - 1.6 8.2 7.4 0.27 10.7 0.7 2.3 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM SARAF PF06682.12 CDJ47014.1 - 1.8 8.1 15.6 0.52 9.9 3.1 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis PIP5K PF01504.18 CDJ47014.1 - 1.9 7.7 17.1 0.023 13.9 1.3 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase PEX11 PF05648.14 CDJ47014.1 - 2.4 7.6 9.4 3.4 7.1 1.6 2.5 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) dsRBD2 PF17842.1 CDJ47014.1 - 2.5 8.3 14.2 0.23 11.7 3.3 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 Pkinase_fungal PF17667.1 CDJ47014.1 - 2.7 6.7 6.7 1.8 7.3 0.3 2.1 2 0 0 2 2 2 0 Fungal protein kinase SLC12 PF03522.15 CDJ47014.1 - 2.9 6.8 22.1 2.3 7.2 8.1 2.2 2 0 0 2 2 2 0 Solute carrier family 12 LMBR1 PF04791.16 CDJ47014.1 - 3.5 6.4 13.1 17 4.2 13.4 1.8 1 1 1 2 2 1 0 LMBR1-like membrane protein EMC3_TMCO1 PF01956.16 CDJ47014.1 - 3.5 7.3 14.2 0.11 12.2 1.1 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like EOS1 PF12326.8 CDJ47014.1 - 3.8 7.4 12.2 3.3 7.6 5.4 2.4 2 1 0 2 2 2 0 N-glycosylation protein MDM10 PF12519.8 CDJ47014.1 - 4 6.2 16.5 0.21 10.4 1.7 2.2 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 Folate_carrier PF01770.18 CDJ47014.1 - 4.2 6.0 14.1 0.1 11.3 0.7 2.7 3 0 0 3 3 2 0 Reduced folate carrier SPX PF03105.19 CDJ47014.1 - 4.8 7.0 21.0 70 3.2 20.1 2.3 1 1 0 1 1 1 0 SPX domain FAM176 PF14851.6 CDJ47014.1 - 5 6.8 21.2 0.08 12.6 0.4 3.1 3 0 0 3 3 3 0 FAM176 family Peptidase_M56 PF05569.11 CDJ47014.1 - 5.1 6.2 8.7 0.098 11.8 0.7 2.1 2 0 0 2 2 1 0 BlaR1 peptidase M56 Rgp1 PF08737.10 CDJ47014.1 - 5.5 6.1 15.1 1.3 8.1 2.0 2.2 2 0 0 2 2 2 0 Rgp1 Nucleoside_tran PF01733.18 CDJ47014.1 - 7 5.9 11.4 0.49 9.7 2.4 2.4 2 1 0 2 2 2 0 Nucleoside transporter eIF-3_zeta PF05091.12 CDJ47014.1 - 7 5.5 32.1 3.4 6.5 6.3 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FemAB PF02388.16 CDJ47014.1 - 7.7 5.3 24.1 1.2 7.9 8.4 2.2 2 0 0 2 2 2 0 FemAB family SUFU_C PF12470.8 CDJ47014.1 - 7.8 6.5 15.2 7 6.6 6.1 2.4 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain Membralin PF09746.9 CDJ47014.1 - 8 5.4 12.3 2.1 7.3 3.7 2.2 2 0 0 2 2 2 0 Tumour-associated protein Renin_r PF07850.14 CDJ47014.1 - 9.1 7.0 11.9 0.23 12.1 0.4 2.9 3 0 0 3 3 2 0 Renin receptor-like protein Presenilin PF01080.17 CDJ47014.1 - 9.9 4.8 36.4 1.8e+04 -6.3 36.4 2.3 1 1 0 1 1 0 0 Presenilin DUF1645 PF07816.11 CDJ47015.1 - 0.00037 21.1 14.4 0.00037 21.1 14.4 5.5 4 2 1 5 5 5 1 Protein of unknown function (DUF1645) ATG22 PF11700.8 CDJ47015.1 - 0.0024 16.6 1.5 0.0024 16.6 1.5 2.7 3 0 0 3 3 3 1 Vacuole effluxer Atg22 like zf-rbx1 PF12678.7 CDJ47015.1 - 0.046 14.0 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger domain AI-2E_transport PF01594.16 CDJ47015.1 - 0.51 9.4 2.2 1.1 8.4 2.2 1.5 1 0 0 1 1 1 0 AI-2E family transporter Connexin PF00029.19 CDJ47015.1 - 6.3 6.5 29.7 0.075 12.8 0.7 3.6 3 0 0 3 3 3 0 Connexin RNA_pol_L_2 PF13656.6 CDJ47016.1 - 6.4e-25 86.7 0.0 9.8e-25 86.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CDJ47016.1 - 1.4e-06 27.6 0.0 2.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DnaJ-X PF14308.6 CDJ47016.1 - 0.01 15.3 7.3 0.01 15.3 7.3 3.7 2 1 1 3 3 3 0 X-domain of DnaJ-containing SUIM_assoc PF16619.5 CDJ47016.1 - 0.021 14.9 14.1 0.021 14.9 14.1 8.5 5 3 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 Connexin PF00029.19 CDJ47016.1 - 1.6 8.5 38.9 0.26 11.0 0.5 4.2 4 0 0 4 4 4 0 Connexin HC2 PF07382.11 CDJ47017.1 - 4.7e-05 23.6 29.5 4.7e-05 23.6 29.5 3.4 3 1 0 3 3 3 1 Histone H1-like nucleoprotein HC2 RskA PF10099.9 CDJ47018.1 - 0.0048 17.2 1.5 0.0048 17.2 1.5 5.6 3 2 1 4 4 4 2 Anti-sigma-K factor rskA Sulf_transp PF04143.14 CDJ47018.1 - 6.3 6.3 4.8 3.8 7.0 0.1 2.6 2 0 0 2 2 2 0 Sulphur transport RR_TM4-6 PF06459.12 CDJ47019.1 - 2 8.2 29.4 2.5 7.9 29.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tyrosinase PF00264.20 CDJ47019.1 - 3.9 7.7 16.2 5.5 7.2 16.2 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase TT_ORF1 PF02956.14 CDJ47019.1 - 7 5.2 23.5 9.1 4.8 23.5 1.1 1 0 0 1 1 1 0 TT viral orf 1 CcmF_C PF16327.5 CDJ47019.1 - 8.9 5.5 11.5 11 5.2 11.5 1.1 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal CDC45 PF02724.14 CDJ47020.1 - 2.8 6.1 22.2 2.7 6.2 10.8 2.2 2 0 0 2 2 2 0 CDC45-like protein Folliculin PF11704.8 CDJ47021.1 - 0.13 12.2 8.7 0.14 12.1 8.7 1.0 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Hom_end_hint PF05203.16 CDJ47021.1 - 0.28 11.1 5.1 0.33 10.9 5.1 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint CLN3 PF02487.17 CDJ47021.1 - 5.8 5.9 8.2 6 5.8 8.2 1.0 1 0 0 1 1 1 0 CLN3 protein DUF2722 PF10846.8 CDJ47023.1 - 0.0083 15.1 7.5 0.0096 14.9 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) PepSY_TM PF03929.16 CDJ47023.1 - 0.016 14.9 0.2 0.016 14.9 0.2 1.1 1 0 0 1 1 1 0 PepSY-associated TM region DUF2058 PF09831.9 CDJ47023.1 - 0.021 15.0 6.9 0.03 14.5 6.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) TRAP_alpha PF03896.16 CDJ47023.1 - 0.033 13.4 0.5 0.04 13.1 0.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 CDJ47023.1 - 0.033 12.9 1.2 0.03 13.1 1.2 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ47023.1 - 0.047 13.3 12.4 0.056 13.0 12.4 1.1 1 0 0 1 1 1 0 Spt20 family Spore_coat_CotO PF14153.6 CDJ47023.1 - 0.083 12.8 9.5 0.11 12.4 9.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Connexin PF00029.19 CDJ47023.1 - 0.11 12.3 2.7 0.14 11.9 2.7 1.1 1 0 0 1 1 1 0 Connexin Androgen_recep PF02166.16 CDJ47023.1 - 0.15 10.9 11.2 0.19 10.5 11.2 1.1 1 0 0 1 1 1 0 Androgen receptor Peroxin-13_N PF04088.13 CDJ47023.1 - 0.47 10.7 1.8 0.71 10.1 1.8 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Roughex PF06020.11 CDJ47023.1 - 0.65 9.0 8.1 0.91 8.5 8.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Ctr PF04145.15 CDJ47023.1 - 1.1 9.9 2.9 1.5 9.5 2.9 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Med3 PF11593.8 CDJ47023.1 - 1.4 8.1 9.3 1.6 7.9 9.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4834 PF16118.5 CDJ47023.1 - 2.6 9.1 7.1 0.58 11.2 4.1 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) CLN3 PF02487.17 CDJ47023.1 - 3.7 6.5 3.5 4.5 6.2 3.5 1.1 1 0 0 1 1 1 0 CLN3 protein DUF3464 PF11947.8 CDJ47023.1 - 8.3 6.1 7.4 12 5.6 7.4 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SR-25 PF10500.9 CDJ47024.1 - 0.002 17.8 15.1 0.0031 17.2 15.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ47024.1 - 0.014 15.0 20.5 0.018 14.7 20.5 1.1 1 0 0 1 1 1 0 Spt20 family FAM60A PF15396.6 CDJ47024.1 - 0.025 14.6 4.7 0.032 14.2 4.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A eIF-3_zeta PF05091.12 CDJ47024.1 - 0.061 12.3 6.4 0.069 12.1 6.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF966 PF06136.13 CDJ47024.1 - 0.063 13.0 7.7 0.069 12.9 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Sporozoite_P67 PF05642.11 CDJ47024.1 - 0.091 10.8 6.2 0.032 12.3 3.9 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen GREB1 PF15782.5 CDJ47024.1 - 0.11 9.6 13.1 0.12 9.4 13.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MRP-S31 PF15433.6 CDJ47024.1 - 0.11 12.1 5.7 0.14 11.8 5.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 RR_TM4-6 PF06459.12 CDJ47024.1 - 0.14 12.0 5.6 0.17 11.7 5.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 CDJ47024.1 - 0.14 10.9 7.9 0.17 10.7 7.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF755 PF05501.11 CDJ47024.1 - 0.15 12.4 21.6 0.2 12.0 21.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Plasmodium_Vir PF05795.11 CDJ47024.1 - 0.18 11.2 4.9 0.22 10.9 4.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DDHD PF02862.17 CDJ47024.1 - 0.21 11.7 5.9 0.25 11.5 5.9 1.2 1 0 0 1 1 1 0 DDHD domain Miga PF10265.9 CDJ47024.1 - 0.33 9.9 7.8 0.35 9.8 7.8 1.1 1 0 0 1 1 1 0 Mitoguardin SRP-alpha_N PF04086.13 CDJ47024.1 - 0.36 10.7 9.2 0.42 10.5 9.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pox_A12 PF04651.13 CDJ47024.1 - 0.37 10.8 5.8 0.56 10.2 5.8 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein TERB2 PF15101.6 CDJ47024.1 - 0.48 10.5 10.9 0.65 10.0 10.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CLN3 PF02487.17 CDJ47024.1 - 0.56 9.2 2.7 0.66 9.0 2.7 1.2 1 0 0 1 1 1 0 CLN3 protein Hid1 PF12722.7 CDJ47024.1 - 0.67 8.0 7.0 0.7 7.9 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lin-8 PF03353.15 CDJ47024.1 - 0.85 9.1 14.3 1.1 8.8 14.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MMU163 PF17119.5 CDJ47024.1 - 0.94 8.6 5.6 1.3 8.1 5.6 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Herpes_pp85 PF04637.12 CDJ47024.1 - 1.4 7.2 7.4 2.1 6.7 7.4 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) NEMP PF10225.9 CDJ47024.1 - 1.5 8.4 4.4 1.9 8.1 4.4 1.1 1 0 0 1 1 1 0 NEMP family Presenilin PF01080.17 CDJ47024.1 - 1.5 7.5 12.7 2 7.1 12.7 1.1 1 0 0 1 1 1 0 Presenilin DUF702 PF05142.12 CDJ47024.1 - 2 8.9 11.4 3.3 8.2 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) PAT1 PF09770.9 CDJ47024.1 - 2.1 6.5 15.2 2.2 6.4 15.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOG2 PF10428.9 CDJ47024.1 - 2.6 7.1 18.9 3.1 6.9 18.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.13 CDJ47024.1 - 3.1 7.3 9.9 4 7.0 9.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF853 PF05872.12 CDJ47024.1 - 3.9 6.0 11.1 5.7 5.4 11.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF572 PF04502.13 CDJ47025.1 - 0.00088 19.0 2.3 0.0012 18.6 2.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) SUIM_assoc PF16619.5 CDJ47025.1 - 0.0011 19.0 1.2 0.0011 19.0 1.2 3.9 2 1 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 Suf PF05843.14 CDJ47025.1 - 0.053 13.5 14.9 0.076 13.0 14.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2828 PF11443.8 CDJ47025.1 - 0.055 11.6 5.9 0.087 10.9 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.16 CDJ47025.1 - 0.19 11.7 9.8 0.28 11.2 9.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 CDJ47025.1 - 0.21 10.6 9.6 0.29 10.1 9.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 HA2 PF04408.23 CDJ47025.1 - 0.24 11.7 4.3 2.1 8.6 3.9 2.2 2 0 0 2 2 2 0 Helicase associated domain (HA2) SAPS PF04499.15 CDJ47025.1 - 0.49 9.1 7.9 0.64 8.7 7.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Connexin PF00029.19 CDJ47025.1 - 0.62 9.8 6.0 0.35 10.6 2.7 1.8 2 0 0 2 2 2 0 Connexin FHIPEP PF00771.20 CDJ47025.1 - 0.72 8.3 5.8 1.1 7.6 5.8 1.3 1 0 0 1 1 1 0 FHIPEP family DUF2407 PF10302.9 CDJ47025.1 - 1.3 9.6 5.9 12 6.6 4.8 2.2 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain dsRBD2 PF17842.1 CDJ47025.1 - 2 8.6 10.0 6.8 6.9 5.3 2.8 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 SRP-alpha_N PF04086.13 CDJ47025.1 - 2.1 8.2 15.8 2.9 7.7 15.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FAM199X PF15814.5 CDJ47025.1 - 2.1 7.3 9.8 3.5 6.6 9.8 1.4 1 0 0 1 1 1 0 Protein family FAM199X Rsc14 PF08586.10 CDJ47025.1 - 2.7 8.9 10.2 3.7 8.4 5.6 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit SPX PF03105.19 CDJ47025.1 - 3.9 7.3 14.3 5.8 6.7 14.3 1.1 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 CDJ47025.1 - 6.2 5.4 13.3 8 5.0 13.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4407 PF14362.6 CDJ47025.1 - 6.2 6.1 24.5 9.3 5.5 24.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VWC PF00093.18 CDJ47026.1 - 0.031 14.6 8.1 0.086 13.2 8.1 1.7 1 0 0 1 1 1 0 von Willebrand factor type C domain DUF4769 PF15992.5 CDJ47026.1 - 0.066 13.0 10.7 0.12 12.1 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) GEMIN8 PF15348.6 CDJ47026.1 - 0.75 10.0 17.4 0.95 9.7 17.0 1.4 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 UNC-79 PF14776.6 CDJ47026.1 - 3.5 6.3 10.3 4.9 5.8 10.3 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 SWI-SNF_Ssr4 PF08549.10 CDJ47026.1 - 9.4 4.7 13.8 12 4.4 13.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) CobT PF06213.12 CDJ47027.1 - 0.001 18.6 23.5 0.001 18.6 23.5 5.0 3 1 2 5 5 5 2 Cobalamin biosynthesis protein CobT Macoilin PF09726.9 CDJ47027.1 - 0.0013 17.5 7.3 0.0013 17.5 7.3 3.7 3 1 0 3 3 3 2 Macoilin family SR-25 PF10500.9 CDJ47027.1 - 0.0069 16.0 24.1 0.0069 16.0 24.1 4.4 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.7 CDJ47027.1 - 0.013 15.3 14.5 0.013 15.3 14.5 4.4 3 1 0 3 3 3 0 SpoIIIAH-like protein DUF720 PF05302.11 CDJ47029.1 - 1.1 9.1 11.5 1.1 9.2 9.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF720) RskA PF10099.9 CDJ47030.1 - 0.049 13.9 9.8 0.073 13.4 9.8 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Pam16 PF03656.13 CDJ47030.1 - 0.093 12.7 5.0 0.18 11.8 5.0 1.5 1 0 0 1 1 1 0 Pam16 Ribosomal_60s PF00428.19 CDJ47030.1 - 0.75 10.4 13.9 1.4 9.6 13.9 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ47030.1 - 1.3 8.9 19.3 1.5 8.8 19.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dehydrin PF00257.19 CDJ47030.1 - 3.9 8.0 21.2 11 6.6 21.2 1.8 1 1 0 1 1 1 0 Dehydrin DUF3947 PF13135.6 CDJ47032.1 - 0.0048 17.1 16.7 0.076 13.2 9.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3947) IMUP PF15761.5 CDJ47032.1 - 0.072 13.8 34.4 0.27 11.9 4.4 3.2 3 0 0 3 3 3 0 Immortalisation up-regulated protein SOBP PF15279.6 CDJ47032.1 - 0.95 10.0 20.3 1.1 9.8 20.3 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Ribosomal_60s PF00428.19 CDJ47032.1 - 3.6 8.3 13.0 1 10.0 3.9 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Med29 PF11568.8 CDJ47032.1 - 5.1 7.3 13.5 2.6 8.2 2.6 2.2 2 0 0 2 2 2 0 Mediator complex subunit 29 DUF2802 PF10975.8 CDJ47032.1 - 6.2 7.0 13.7 14 5.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Activator_LAG-3 PF11498.8 CDJ47036.1 - 0.69 8.8 33.1 0.7 8.8 33.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ47036.1 - 1.7 8.6 23.5 2 8.3 23.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RCR PF12273.8 CDJ47036.1 - 5.3 7.7 14.3 11 6.7 14.3 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Presenilin PF01080.17 CDJ47036.1 - 5.8 5.6 9.0 6.4 5.4 9.0 1.0 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ47036.1 - 6.9 6.7 6.3 8.1 6.4 6.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ47038.1 - 0.079 13.0 40.0 0.12 12.4 40.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ47038.1 - 6.1 6.5 6.7 9.8 5.9 6.7 1.3 1 0 0 1 1 1 0 Connexin FAT PF02259.23 CDJ47039.1 - 2.4e-17 63.2 6.7 2.4e-17 63.2 6.7 3.8 4 1 0 4 4 4 1 FAT domain Spt20 PF12090.8 CDJ47039.1 - 0.00039 20.1 20.9 0.00039 20.1 20.9 6.3 5 2 1 6 6 6 3 Spt20 family PI3_PI4_kinase PF00454.27 CDJ47039.1 - 0.31 10.8 3.9 0.085 12.7 0.3 1.9 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase AF-4 PF05110.13 CDJ47039.1 - 0.99 7.4 111.4 0.0032 15.7 16.7 5.3 5 0 0 5 5 5 0 AF-4 proto-oncoprotein Neur_chan_memb PF02932.16 CDJ47039.1 - 5.9 6.9 38.7 4.2 7.4 3.3 4.6 4 1 0 4 4 4 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 CDJ47039.1 - 7 5.4 64.9 0.55 9.0 12.1 4.4 4 0 0 4 4 4 0 Golgi-body localisation protein domain UQ_con PF00179.26 CDJ47040.1 - 7.2e-14 51.6 0.0 7.8e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme XPG_I PF00867.18 CDJ47041.1 - 1.4e-07 31.7 0.0 3.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region TetR_C_1 PF02909.17 CDJ47041.1 - 0.081 12.7 0.2 0.19 11.6 0.2 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TSP_1 PF00090.19 CDJ47042.1 - 3e-97 318.7 226.6 6.4e-13 48.7 5.9 19.6 18 1 0 18 18 18 15 Thrombospondin type 1 domain Notch PF00066.17 CDJ47042.1 - 7.8e-25 87.0 90.6 2.1e-07 31.3 14.0 8.6 6 0 0 6 6 6 4 LNR domain ShK PF01549.24 CDJ47042.1 - 1.6 9.3 79.6 0.069 13.7 0.5 14.5 12 0 0 12 12 12 0 ShK domain-like LMF1 PF06762.14 CDJ47043.1 - 3.8e-53 181.2 0.2 5.8e-53 180.6 0.2 1.3 1 0 0 1 1 1 1 Lipase maturation factor SUIM_assoc PF16619.5 CDJ47043.1 - 1.7e-06 27.9 3.1 0.00054 20.0 0.1 7.3 4 1 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 RCR PF12273.8 CDJ47043.1 - 0.047 14.3 0.1 0.047 14.3 0.1 3.9 4 1 0 4 4 4 0 Chitin synthesis regulation, resistance to Congo red DUF1772 PF08592.11 CDJ47043.1 - 0.063 13.6 5.6 4 7.7 2.3 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) FAM176 PF14851.6 CDJ47043.1 - 4.9 6.8 0.0 4.9 6.8 0.0 5.5 3 1 2 5 5 5 0 FAM176 family SUIM_assoc PF16619.5 CDJ47044.1 - 1.9e-08 34.2 6.4 0.001 19.1 0.1 2.4 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Sin_N PF04801.13 CDJ47044.1 - 0.0066 15.7 0.1 0.0066 15.7 0.1 1.7 2 1 0 2 2 2 1 Sin-like protein conserved region Spt20 PF12090.8 CDJ47044.1 - 0.0097 15.5 17.5 0.036 13.7 8.9 2.3 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ47044.1 - 0.018 14.0 13.2 0.015 14.3 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ47044.1 - 1.5 9.8 6.9 4.9 8.2 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4820 PF16091.5 CDJ47044.1 - 3.4 7.0 7.2 2.9 7.2 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF3824 PF12868.7 CDJ47045.1 - 0.008 16.8 2.7 0.01 16.5 2.7 1.2 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) RskA PF10099.9 CDJ47045.1 - 0.11 12.8 9.3 0.16 12.2 9.3 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3138 PF11336.8 CDJ47045.1 - 0.27 9.8 3.7 0.3 9.7 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SPAN PF02510.14 CDJ47045.1 - 0.85 8.7 5.2 1 8.4 5.2 1.2 1 0 0 1 1 1 0 Surface presentation of antigens protein DUF4719 PF15843.5 CDJ47046.1 - 0.24 11.5 3.0 0.94 9.6 3.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) DUF1943 PF09172.11 CDJ47046.1 - 1.8 7.7 8.0 0.12 11.6 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) QCR10 PF09796.9 CDJ47047.1 - 0.12 12.5 0.3 0.12 12.5 0.3 3.8 2 1 2 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) MOZART1 PF12554.8 CDJ47049.1 - 0.036 13.8 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Kinesin_assoc PF16183.5 CDJ47050.1 - 1.7 8.7 10.5 1.9 8.6 10.5 1.0 1 0 0 1 1 1 0 Kinesin-associated AF-4 PF05110.13 CDJ47051.1 - 5.7e-06 24.8 45.2 5.7e-06 24.8 45.2 4.1 4 0 0 4 4 4 1 AF-4 proto-oncoprotein OTU PF02338.19 CDJ47051.1 - 0.00036 21.0 0.0 0.00036 21.0 0.0 2.6 3 0 0 3 3 3 1 OTU-like cysteine protease SPX PF03105.19 CDJ47051.1 - 0.002 18.1 1.7 0.002 18.1 1.7 5.1 3 1 1 4 4 4 1 SPX domain Spt20 PF12090.8 CDJ47051.1 - 0.0071 16.0 14.6 0.0071 16.0 14.6 5.4 5 1 0 5 5 5 2 Spt20 family NAM-associated PF14303.6 CDJ47051.1 - 0.2 12.4 0.0 0.2 12.4 0.0 6.5 4 2 2 6 6 6 0 No apical meristem-associated C-terminal domain eIF-3_zeta PF05091.12 CDJ47052.1 - 0.18 10.7 26.8 0.19 10.6 26.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_23 PF13476.6 CDJ47052.1 - 0.26 11.7 21.7 0.3 11.5 21.7 1.2 1 0 0 1 1 1 0 AAA domain TCP PF03634.13 CDJ47052.1 - 0.41 11.2 27.8 0.5 10.9 27.8 1.1 1 0 0 1 1 1 0 TCP family transcription factor Velvet PF11754.8 CDJ47052.1 - 0.45 10.4 24.6 0.61 10.0 24.6 1.3 1 0 0 1 1 1 0 Velvet factor SprA-related PF12118.8 CDJ47052.1 - 0.68 9.0 47.9 0.87 8.7 47.9 1.1 1 0 0 1 1 1 0 SprA-related family FAM199X PF15814.5 CDJ47052.1 - 0.79 8.7 22.3 0.95 8.5 22.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X TFIIA PF03153.13 CDJ47052.1 - 1 9.3 51.7 1.3 9.0 51.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_U57 PF05582.12 CDJ47052.1 - 1.4 8.1 16.5 1.6 7.9 16.5 1.2 1 0 0 1 1 1 0 YabG peptidase U57 RAP1 PF07218.11 CDJ47052.1 - 1.6 6.9 6.2 1.8 6.7 6.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2126 PF09899.9 CDJ47052.1 - 2 6.4 14.0 1.8 6.5 14.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF3824 PF12868.7 CDJ47052.1 - 2.4 8.8 22.6 0.83 10.3 19.5 1.8 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Serinc PF03348.15 CDJ47052.1 - 2.6 6.9 14.8 3 6.6 14.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) BAF1_ABF1 PF04684.13 CDJ47052.1 - 3 6.8 24.4 3.3 6.7 24.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.9 CDJ47052.1 - 3.4 5.8 35.2 3.6 5.7 35.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.6 CDJ47052.1 - 3.5 7.6 22.4 5 7.1 22.4 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Dsh_C PF12316.8 CDJ47052.1 - 4 7.8 27.9 4.5 7.6 27.9 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Endostatin PF06482.11 CDJ47052.1 - 4.4 6.7 22.7 5 6.5 22.7 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Presenilin PF01080.17 CDJ47052.1 - 5.2 5.7 32.9 6.5 5.4 32.9 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ47052.1 - 5.3 6.8 28.0 6.4 6.5 28.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_60s PF00428.19 CDJ47052.1 - 5.8 7.6 11.8 5.8 7.6 10.7 1.8 1 1 1 2 2 2 0 60s Acidic ribosomal protein CCSAP PF15748.5 CDJ47052.1 - 7.8 6.6 36.5 9.5 6.3 36.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF572 PF04502.13 CDJ47052.1 - 8.4 5.9 26.5 9.2 5.8 26.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Activator_LAG-3 PF11498.8 CDJ47052.1 - 8.7 5.2 60.9 12 4.8 60.9 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SR-25 PF10500.9 CDJ47052.1 - 9.3 5.8 37.6 15 5.1 37.6 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PPP4R2 PF09184.11 CDJ47052.1 - 9.3 5.7 20.7 9.9 5.7 20.7 1.1 1 0 0 1 1 1 0 PPP4R2 NTP_transf_2 PF01909.23 CDJ47054.1 - 2.2e-06 27.9 0.0 4.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain SUIM_assoc PF16619.5 CDJ47054.1 - 0.00047 20.2 0.0 0.00047 20.2 0.0 9.3 5 3 4 9 9 9 3 Unstructured region C-term to UIM in Ataxin3 PAP_assoc PF03828.19 CDJ47054.1 - 0.001 19.2 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase SR-25 PF10500.9 CDJ47054.1 - 0.0097 15.5 12.9 0.0097 15.5 12.9 6.2 3 2 3 6 6 6 1 Nuclear RNA-splicing-associated protein FbpA PF05833.11 CDJ47054.1 - 0.013 14.3 0.3 0.013 14.3 0.3 3.0 3 1 0 3 3 3 0 Fibronectin-binding protein A N-terminus (FbpA) Polbeta PF18765.1 CDJ47054.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Apt1 PF10351.9 CDJ47054.1 - 6.3 5.5 36.3 0.21 10.4 18.6 2.8 2 1 0 2 2 2 0 Golgi-body localisation protein domain Prp18 PF02840.15 CDJ47056.1 - 6.9e-16 58.6 0.7 6.9e-16 58.6 0.7 2.4 2 2 1 3 3 3 1 Prp18 domain PRP4 PF08799.11 CDJ47056.1 - 3.5e-10 39.3 0.5 6.6e-10 38.4 0.5 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like dsRBD2 PF17842.1 CDJ47056.1 - 0.19 11.9 1.7 0.73 10.0 1.7 2.0 1 1 0 1 1 1 0 Double-stranded RNA binding domain 2 CDC45 PF02724.14 CDJ47056.1 - 0.44 8.8 7.8 0.56 8.4 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-RVT PF13966.6 CDJ47058.1 - 3.7e-06 27.6 0.5 9.2e-06 26.3 0.5 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF4179 PF13786.6 CDJ47058.1 - 0.018 15.5 0.0 0.62 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) AHJR-like PF18743.1 CDJ47058.1 - 0.048 13.2 0.4 1.1 8.8 0.2 2.3 1 1 1 2 2 2 0 REase_AHJR-like RVT_1 PF00078.27 CDJ47059.1 - 1.4e-05 24.8 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) K_channel_TID PF07941.11 CDJ47060.1 - 0.14 12.6 0.5 0.14 12.6 0.5 4.0 3 1 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Corona_nucleoca PF00937.18 CDJ47060.1 - 0.42 9.6 6.1 0.58 9.1 6.1 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3827 PF12877.7 CDJ47060.1 - 4.8 5.4 7.4 6.5 5.0 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) YlqD PF11068.8 CDJ47061.1 - 0.16 12.4 0.5 0.21 11.9 0.5 1.2 1 0 0 1 1 1 0 YlqD protein DUF2452 PF10504.9 CDJ47061.1 - 0.16 11.5 0.2 0.2 11.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Peptidase_C1 PF00112.23 CDJ47062.1 - 7.2e-50 170.1 2.1 1.1e-49 169.5 2.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 CDJ47062.1 - 0.0098 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 CDJ47062.1 - 0.33 9.7 1.2 5.6 5.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Helicase_C PF00271.31 CDJ47063.1 - 2.2e-07 31.2 1.2 1.2e-06 28.8 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Presenilin PF01080.17 CDJ47063.1 - 0.0002 20.3 4.8 0.0002 20.3 4.8 1.7 2 0 0 2 2 2 1 Presenilin Macoilin PF09726.9 CDJ47063.1 - 0.00036 19.2 15.2 0.00036 19.2 15.2 1.6 2 0 0 2 2 2 1 Macoilin family TFIIA PF03153.13 CDJ47063.1 - 0.00069 19.7 8.1 0.00069 19.7 8.1 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 CDJ47063.1 - 0.0011 18.0 13.6 0.0014 17.5 13.6 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Mem_trans PF03547.18 CDJ47063.1 - 0.012 14.0 0.4 0.015 13.7 0.4 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF2489 PF10675.9 CDJ47063.1 - 0.17 11.8 8.1 0.3 11.0 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) DUF2161 PF09929.9 CDJ47063.1 - 0.5 10.5 5.5 1.4 9.1 0.8 2.5 2 0 0 2 2 2 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) Neur_chan_memb PF02932.16 CDJ47063.1 - 0.62 10.1 8.0 1.2 9.1 8.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Otopetrin PF03189.13 CDJ47063.1 - 0.74 8.6 4.0 1.1 7.9 4.0 1.3 1 0 0 1 1 1 0 Otopetrin Miga PF10265.9 CDJ47063.1 - 2 7.3 19.7 4.3 6.2 19.7 1.4 1 0 0 1 1 1 0 Mitoguardin DDHD PF02862.17 CDJ47063.1 - 2.1 8.5 14.7 0.51 10.5 9.5 2.2 2 0 0 2 2 2 0 DDHD domain CytochromB561_N PF09786.9 CDJ47063.1 - 3.4 6.5 18.4 4.5 6.2 18.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF4647 PF15504.6 CDJ47063.1 - 5.7 5.9 15.5 8.1 5.4 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Pap_E4 PF02711.14 CDJ47063.1 - 7.4 7.6 14.9 18 6.4 14.9 1.6 1 0 0 1 1 1 0 E4 protein DUF5558 PF17713.1 CDJ47065.1 - 5.9 7.3 16.5 0.053 13.9 6.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5558) Brix PF04427.18 CDJ47067.1 - 3e-07 30.7 0.1 5.8e-06 26.6 0.1 2.3 1 1 0 1 1 1 1 Brix domain PAP1 PF08601.10 CDJ47067.1 - 0.0064 16.3 0.1 0.0064 16.3 0.1 3.5 2 2 1 3 3 3 1 Transcription factor PAP1 Activator_LAG-3 PF11498.8 CDJ47067.1 - 0.55 9.2 47.2 1.4 7.8 21.0 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SR-25 PF10500.9 CDJ47068.1 - 0.43 10.2 24.6 0.45 10.1 0.8 2.6 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein WRNPLPNID PF15017.6 CDJ47068.1 - 7.3 7.5 12.5 45 5.0 0.0 4.0 4 0 0 4 4 4 0 Putative WW-binding domain and destruction box RCC1_2 PF13540.6 CDJ47069.1 - 0.00069 19.3 11.7 0.23 11.3 0.1 5.7 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat TSP_1 PF00090.19 CDJ47069.1 - 0.018 15.2 0.6 0.041 14.1 0.6 1.6 1 0 0 1 1 1 0 Thrombospondin type 1 domain MMgT PF10270.9 CDJ47069.1 - 0.081 13.3 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Membrane magnesium transporter RCC1 PF00415.18 CDJ47069.1 - 3.4 8.4 5.7 30 5.3 0.4 3.2 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat ANAPC4_WD40 PF12894.7 CDJ47070.1 - 3.4e-05 24.1 0.6 0.037 14.3 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ47070.1 - 0.061 14.2 13.5 2.5 9.1 0.0 6.6 6 0 0 6 6 6 0 WD domain, G-beta repeat Methyltr_RsmB-F PF01189.17 CDJ47071.1 - 1.7e-09 37.6 11.5 2.4e-08 33.9 0.0 2.7 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Presenilin PF01080.17 CDJ47071.1 - 0.045 12.5 14.8 0.051 12.3 14.8 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ47071.1 - 0.38 9.0 28.6 0.43 8.8 28.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.17 CDJ47071.1 - 0.66 10.1 11.8 0.88 9.7 11.8 1.2 1 0 0 1 1 1 0 DDHD domain Suf PF05843.14 CDJ47071.1 - 1.7 8.6 19.8 2.4 8.1 19.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Exonuc_VII_L PF02601.15 CDJ47071.1 - 1.7 8.1 20.8 2.2 7.8 20.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 CDJ47071.1 - 2.1 6.1 12.8 2.8 5.7 12.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med15 PF09606.10 CDJ47071.1 - 2.3 6.8 44.9 2.7 6.6 44.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ndc1_Nup PF09531.10 CDJ47071.1 - 2.5 6.7 17.0 3.1 6.4 17.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.13 CDJ47071.1 - 2.7 7.7 15.9 4 7.2 15.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CCSAP PF15748.5 CDJ47071.1 - 2.9 8.0 19.0 3.9 7.6 19.0 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FAM60A PF15396.6 CDJ47071.1 - 5.9 6.8 15.1 8.2 6.4 15.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hydin_ADK PF17213.3 CDJ47071.1 - 6.4 7.0 15.8 9.6 6.4 15.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RR_TM4-6 PF06459.12 CDJ47071.1 - 6.6 6.5 15.2 10 5.9 15.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 CDJ47071.1 - 7 4.6 14.5 8 4.4 14.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_LMP1 PF05297.11 CDJ47072.1 - 1.1 8.4 5.0 1.2 8.2 5.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Pkinase PF00069.25 CDJ47073.1 - 4.1e-11 42.7 0.0 7.5e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ47073.1 - 2.1e-10 40.4 0.0 7.2e-10 38.6 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ47073.1 - 7.1e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Dehydrin PF00257.19 CDJ47073.1 - 7.4 7.1 10.2 3.6 8.1 7.6 1.8 1 1 0 1 1 1 0 Dehydrin Pkinase PF00069.25 CDJ47074.1 - 9.1e-08 31.8 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ47074.1 - 8.4e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ47074.1 - 0.00082 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SPX PF03105.19 CDJ47075.1 - 8.4 6.2 40.5 0.27 11.1 2.4 2.8 3 0 0 3 3 3 0 SPX domain DUF2722 PF10846.8 CDJ47076.1 - 4.1e-05 22.7 3.8 4.1e-05 22.7 3.8 6.2 4 3 2 6 6 6 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ47076.1 - 0.00014 22.2 5.3 0.00014 22.2 5.3 7.6 2 2 4 6 6 6 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ47076.1 - 0.00073 19.2 11.8 0.00073 19.2 11.8 5.3 3 1 2 5 5 5 3 Nuclear RNA-splicing-associated protein Tim54 PF11711.8 CDJ47076.1 - 0.001 17.9 4.7 0.001 17.9 4.7 3.3 3 0 0 3 3 3 2 Inner membrane protein import complex subunit Tim54 Glt_symporter PF03616.14 CDJ47076.1 - 2.1 6.9 6.9 3.1 6.4 0.8 2.6 2 0 0 2 2 2 0 Sodium/glutamate symporter EOS1 PF12326.8 CDJ47077.1 - 0.57 10.1 4.5 2.3 8.1 4.5 1.8 1 1 0 1 1 1 0 N-glycosylation protein DUF4179 PF13786.6 CDJ47077.1 - 1.6 9.2 6.2 5.2 7.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) PI3K_1B_p101 PF10486.9 CDJ47078.1 - 0.024 12.4 11.6 0.031 12.1 11.6 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Plasmodium_Vir PF05795.11 CDJ47078.1 - 0.72 9.2 20.5 0.037 13.4 15.2 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SR-25 PF10500.9 CDJ47078.1 - 1 8.9 33.8 1.7 8.2 31.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CLN3 PF02487.17 CDJ47078.1 - 1.3 8.0 15.2 2.9 6.9 15.2 1.5 1 0 0 1 1 1 0 CLN3 protein eIF-3_zeta PF05091.12 CDJ47078.1 - 2.4 7.0 23.3 3.7 6.4 23.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Serinc PF03348.15 CDJ47078.1 - 2.6 6.9 9.2 5 5.9 9.2 1.6 1 0 0 1 1 1 0 Serine incorporator (Serinc) Myc_N PF01056.18 CDJ47078.1 - 3.1 7.6 24.9 0.2 11.5 17.0 2.2 2 0 0 2 2 2 0 Myc amino-terminal region Lin-8 PF03353.15 CDJ47079.1 - 0.2 11.2 11.5 0.25 10.9 11.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Striatin PF08232.12 CDJ47079.1 - 0.23 12.0 14.5 0.42 11.2 14.5 1.4 1 0 0 1 1 1 0 Striatin family Neur_chan_memb PF02932.16 CDJ47079.1 - 0.45 10.5 3.4 0.56 10.2 3.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gastrin PF00918.17 CDJ47079.1 - 1.3 10.0 12.1 3.1 8.8 12.1 1.6 1 0 0 1 1 1 0 Gastrin/cholecystokinin family ORC_WH_C PF18137.1 CDJ47079.1 - 1.3 9.1 9.2 2.3 8.3 9.2 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DDHD PF02862.17 CDJ47079.1 - 2.6 8.2 8.0 3.9 7.6 8.0 1.3 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 CDJ47079.1 - 3.6 7.3 12.9 5 6.9 12.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ47079.1 - 4.1 7.3 7.6 6.1 6.8 7.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.9 CDJ47079.1 - 4.5 5.4 21.6 6 5.0 21.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.14 CDJ47079.1 - 4.9 7.0 16.3 7.2 6.5 16.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.8 CDJ47079.1 - 5.5 5.8 37.3 8.6 5.2 37.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SLC12 PF03522.15 CDJ47079.1 - 6.7 5.6 9.6 8.9 5.2 9.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GET2 PF08690.10 CDJ47079.1 - 7.5 6.1 14.5 12 5.5 14.5 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF3464 PF11947.8 CDJ47079.1 - 8.2 6.2 9.3 17 5.1 9.3 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CDC45 PF02724.14 CDJ47079.1 - 9.6 4.4 10.2 14 3.8 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.8 CDJ47080.1 - 0.0021 17.1 8.5 0.0021 17.1 8.5 9.4 8 3 0 9 9 9 2 Protein of unknown function (DUF2722) DUF4079 PF13301.6 CDJ47080.1 - 1.3 9.2 8.5 87 3.3 0.3 6.1 5 2 0 5 5 5 0 Protein of unknown function (DUF4079) Activator_LAG-3 PF11498.8 CDJ47081.1 - 0.00017 20.7 21.6 0.0002 20.5 21.6 1.3 1 0 0 1 1 1 1 Transcriptional activator LAG-3 DUF2205 PF10224.9 CDJ47081.1 - 0.012 15.6 5.2 0.012 15.6 5.2 2.2 1 1 1 2 2 1 0 Short coiled-coil protein Cnn_1N PF07989.11 CDJ47081.1 - 0.037 14.2 2.4 0.037 14.2 2.4 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 CDJ47081.1 - 0.066 13.6 2.4 0.066 13.6 2.4 1.8 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) YabA PF06156.13 CDJ47081.1 - 0.11 13.1 13.1 0.19 12.4 13.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA TFIIA PF03153.13 CDJ47081.1 - 0.17 11.8 30.7 0.23 11.4 30.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ47081.1 - 0.89 7.4 15.4 0.03 12.3 9.7 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 CDJ47081.1 - 1 9.4 20.8 1.6 8.7 20.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ALMT PF11744.8 CDJ47081.1 - 2.9 6.6 11.0 3.7 6.3 11.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Prominin PF05478.11 CDJ47081.1 - 3.7 5.4 7.8 4.7 5.0 7.8 1.0 1 0 0 1 1 1 0 Prominin Nup88 PF10168.9 CDJ47081.1 - 3.9 5.2 12.3 5.1 4.8 12.3 1.1 1 0 0 1 1 1 0 Nuclear pore component MMR1 PF08505.10 CDJ47081.1 - 4.5 7.5 14.3 6.1 7.1 14.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein UPF0242 PF06785.11 CDJ47081.1 - 9.3 6.3 23.0 13 5.8 23.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Borrelia_P83 PF05262.11 CDJ47082.1 - 0.19 10.2 8.3 0.24 9.9 8.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SLC12 PF03522.15 CDJ47082.1 - 0.23 10.5 7.4 0.36 9.8 7.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SRP-alpha_N PF04086.13 CDJ47082.1 - 0.41 10.5 13.3 0.035 14.0 8.2 1.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Nop53 PF07767.11 CDJ47082.1 - 0.7 9.2 15.5 1.6 8.1 15.5 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PAT1 PF09770.9 CDJ47082.1 - 0.76 8.0 25.9 1.1 7.5 25.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.7 CDJ47082.1 - 1 7.4 7.0 1.6 6.7 7.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CLN3 PF02487.17 CDJ47082.1 - 1.4 7.8 3.4 2.4 7.1 3.4 1.5 1 0 0 1 1 1 0 CLN3 protein TCP PF03634.13 CDJ47082.1 - 1.5 9.4 15.6 0.44 11.1 7.4 2.2 2 0 0 2 2 2 0 TCP family transcription factor Macoilin PF09726.9 CDJ47082.1 - 1.9 7.0 16.4 0.56 8.7 5.0 2.3 2 0 0 2 2 2 0 Macoilin family Peptidase_S49_N PF08496.10 CDJ47082.1 - 6.1 6.9 11.2 11 6.0 11.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DDHD PF02862.17 CDJ47082.1 - 7.5 6.6 11.3 1.3 9.1 6.2 2.1 2 0 0 2 2 2 0 DDHD domain FliD_N PF02465.18 CDJ47083.1 - 0.022 15.5 1.2 0.022 15.5 1.2 6.7 4 2 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus Orf78 PF06024.12 CDJ47083.1 - 0.084 13.2 0.2 0.084 13.2 0.2 4.4 3 1 1 4 4 4 0 Orf78 (ac78) DUF975 PF06161.11 CDJ47083.1 - 0.12 12.2 6.9 0.31 10.8 6.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF975) EphA2_TM PF14575.6 CDJ47083.1 - 0.19 12.6 0.1 0.19 12.6 0.1 5.3 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain CDC45 PF02724.14 CDJ47083.1 - 1.1 7.4 33.6 2.1 6.5 33.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.19 CDJ47083.1 - 2.4 8.8 20.8 7 7.3 8.3 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Utp14 PF04615.13 CDJ47083.1 - 3.1 6.3 36.9 21 3.5 0.0 2.0 2 0 0 2 2 2 0 Utp14 protein ADP_ribosyl_GH PF03747.14 CDJ47083.1 - 3.5 7.3 9.8 0.14 11.8 0.8 2.3 2 1 0 2 2 2 0 ADP-ribosylglycohydrolase LAP1C PF05609.12 CDJ47083.1 - 8.8 5.3 46.0 2 7.4 0.6 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Myb_DNA-bind_6 PF13921.6 CDJ47084.1 - 2.5e-05 24.4 1.4 7.5e-05 22.9 1.4 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SR-25 PF10500.9 CDJ47084.1 - 0.0001 22.0 15.5 0.00018 21.2 15.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein FAM117 PF15388.6 CDJ47084.1 - 0.00033 20.2 4.4 0.00061 19.3 4.4 1.4 1 0 0 1 1 1 1 Protein Family FAM117 SANT_DAMP1_like PF16282.5 CDJ47084.1 - 0.00042 20.5 1.0 0.00092 19.4 1.0 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 CDJ47084.1 - 0.00067 19.8 0.6 0.0012 19.0 0.6 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SUIM_assoc PF16619.5 CDJ47084.1 - 0.01 15.8 16.7 0.029 14.4 2.5 3.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AF-4 PF05110.13 CDJ47084.1 - 0.049 11.7 15.6 0.068 11.3 15.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TFIIA PF03153.13 CDJ47084.1 - 0.36 10.8 19.0 0.56 10.1 19.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Menin PF05053.13 CDJ47084.1 - 0.51 8.6 16.2 0.66 8.3 16.2 1.1 1 0 0 1 1 1 0 Menin Herpes_pp85 PF04637.12 CDJ47084.1 - 0.78 8.1 5.1 1.1 7.6 5.1 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Neur_chan_memb PF02932.16 CDJ47084.1 - 1.1 9.2 2.5 1.4 8.9 2.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RIFIN PF02009.16 CDJ47084.1 - 3 7.6 6.8 5.2 6.9 6.8 1.3 1 0 0 1 1 1 0 Rifin SLC12 PF03522.15 CDJ47084.1 - 4.4 6.2 6.6 5.9 5.8 6.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4692 PF15763.5 CDJ47084.1 - 4.6 7.7 9.1 2.1 8.8 6.6 1.7 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) GREB1 PF15782.5 CDJ47084.1 - 5 4.1 8.1 6 3.9 8.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 CDJ47084.1 - 9.3 5.0 11.7 12 4.6 11.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.25 CDJ47085.1 - 3.6e-08 33.1 0.0 5.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CDJ47085.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 CDJ47085.1 - 0.043 13.1 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Hid1 PF12722.7 CDJ47085.1 - 0.046 11.8 1.6 0.072 11.2 1.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPX PF03105.19 CDJ47085.1 - 0.76 9.6 13.9 1.1 9.2 13.9 1.3 1 1 0 1 1 1 0 SPX domain TFIIA PF03153.13 CDJ47087.1 - 0.00015 21.9 57.1 0.00025 21.2 57.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3668 PF12416.8 CDJ47087.1 - 0.022 14.6 0.5 0.022 14.6 0.5 2.4 2 1 1 3 3 3 0 Cep120 protein ASC PF00858.24 CDJ47087.1 - 0.044 12.7 3.8 0.074 12.0 3.8 1.3 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Med15 PF09606.10 CDJ47087.1 - 0.77 8.4 60.8 0.93 8.1 60.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.9 CDJ47087.1 - 3.5 7.2 52.8 0.2 11.2 25.4 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ47088.1 - 0.016 14.8 9.9 0.015 14.9 9.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF4736 PF15883.5 CDJ47088.1 - 0.018 14.8 1.8 0.023 14.4 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) Androgen_recep PF02166.16 CDJ47088.1 - 0.092 11.6 9.7 0.085 11.7 9.7 1.1 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 CDJ47088.1 - 0.15 12.0 11.1 0.15 12.0 11.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 CDJ47088.1 - 3.7 6.6 12.5 4.5 6.4 12.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2967 PF11179.8 CDJ47088.1 - 7.5 4.5 14.3 8.9 4.3 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) TFIIF_beta PF02270.15 CDJ47089.1 - 0.0016 18.5 0.1 0.0034 17.5 0.1 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain RPA_C PF08784.11 CDJ47089.1 - 0.01 16.4 0.5 0.077 13.7 0.1 2.1 1 1 1 2 2 2 0 Replication protein A C terminal THOC7 PF05615.13 CDJ47089.1 - 0.012 15.9 0.1 0.014 15.7 0.1 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 rve PF00665.26 CDJ47094.1 - 4e-10 39.9 0.1 8.2e-10 38.9 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDJ47094.1 - 0.03 14.1 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain HATPase_c_2 PF13581.6 CDJ47094.1 - 0.046 13.7 0.0 0.65 10.0 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain BID PF06393.11 CDJ47094.1 - 0.071 12.6 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) EcKinase PF02958.20 CDJ47094.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase RNA_pol_Rpb1_5 PF04998.17 CDJ47095.1 - 8.6e-77 258.2 0.1 1.7e-75 253.9 0.2 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CDJ47095.1 - 3.2e-54 183.6 3.6 6.6e-37 127.3 0.0 3.7 4 0 0 4 4 4 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CDJ47095.1 - 1.6e-23 83.4 0.0 2.9e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CDJ47095.1 - 2.3e-15 56.4 0.1 1.4e-14 54.0 0.1 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 CDJ47095.1 - 3.5e-15 56.1 0.2 7.1e-13 48.6 0.0 4.0 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 Mem_trans PF03547.18 CDJ47095.1 - 2.2 6.6 4.5 3.9 5.8 4.5 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF2722 PF10846.8 CDJ47097.1 - 0.001 18.1 8.6 0.0013 17.8 8.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ47097.1 - 0.0051 16.9 11.9 0.0061 16.6 11.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Adaptin_binding PF10199.9 CDJ47097.1 - 0.012 16.3 1.2 0.23 12.1 1.4 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Neur_chan_memb PF02932.16 CDJ47097.1 - 0.031 14.4 0.5 0.051 13.6 0.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TMEM51 PF15345.6 CDJ47097.1 - 0.064 13.1 3.9 2.2 8.1 3.4 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 UPF0560 PF10577.9 CDJ47097.1 - 0.1 11.1 9.2 0.18 10.3 9.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Spt20 PF12090.8 CDJ47097.1 - 0.29 10.7 21.0 0.45 10.1 21.0 1.3 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ47097.1 - 0.58 9.2 4.1 0.8 8.7 4.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein MTP18 PF10558.9 CDJ47097.1 - 0.84 9.6 5.0 3.9 7.4 3.0 2.6 1 1 1 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) Med3 PF11593.8 CDJ47097.1 - 1.8 7.7 14.5 2.7 7.1 14.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4834 PF16118.5 CDJ47097.1 - 5.2 8.1 11.5 0.23 12.4 2.3 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) OppC_N PF12911.7 CDJ47097.1 - 6.8 6.8 8.8 6.5 6.8 3.2 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C PDEase_I PF00233.19 CDJ47099.1 - 6.7e-16 58.7 1.1 6.7e-16 58.7 1.1 3.1 2 2 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase TFIIA PF03153.13 CDJ47099.1 - 0.00022 21.3 18.3 0.00034 20.7 18.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pox_G7 PF05503.12 CDJ47099.1 - 0.023 13.7 1.9 0.034 13.1 1.9 1.2 1 0 0 1 1 1 0 Poxvirus G7-like HD PF01966.22 CDJ47099.1 - 0.098 12.9 0.1 0.44 10.8 0.0 2.2 3 0 0 3 3 3 0 HD domain Peptidase_S49_N PF08496.10 CDJ47099.1 - 0.49 10.4 11.5 1.6 8.8 5.9 3.0 4 0 0 4 4 4 0 Peptidase family S49 N-terminal Connexin PF00029.19 CDJ47099.1 - 5 6.8 8.8 13 5.4 4.8 2.4 2 0 0 2 2 2 0 Connexin Nop14 PF04147.12 CDJ47100.1 - 0.028 12.7 37.6 0.037 12.3 37.6 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 CDJ47100.1 - 0.19 9.8 42.8 0.23 9.5 42.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VIR_N PF15912.5 CDJ47100.1 - 2 7.9 40.6 2.7 7.5 40.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Apt1 PF10351.9 CDJ47100.1 - 4.3 6.1 30.9 6.4 5.5 30.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 CDJ47100.1 - 4.3 4.3 43.1 5.1 4.1 43.1 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Dapper PF15268.6 CDJ47100.1 - 5.7 5.7 53.0 7.1 5.4 53.0 1.2 1 0 0 1 1 1 0 Dapper DUF1345 PF07077.11 CDJ47101.1 - 1.1 9.0 3.7 0.56 9.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) LON_substr_bdg PF02190.16 CDJ47102.1 - 1.4e-08 34.8 0.1 1.4e-08 34.8 0.1 4.0 3 1 0 3 3 3 2 ATP-dependent protease La (LON) substrate-binding domain AAA_PrkA PF08298.11 CDJ47102.1 - 2.9e-06 26.5 0.0 6.4e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA PF00004.29 CDJ47102.1 - 1.2e-05 25.7 2.0 1.7e-05 25.3 0.0 2.4 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ47102.1 - 6.5e-05 23.0 0.0 0.0002 21.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDJ47102.1 - 0.00044 20.0 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ47102.1 - 0.00056 20.3 0.0 0.00056 20.3 0.0 4.7 3 2 0 3 3 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ47102.1 - 0.001 19.4 1.8 0.066 13.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CDJ47102.1 - 0.0071 16.1 1.6 0.02 14.6 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 CDJ47102.1 - 0.011 16.2 0.5 0.068 13.7 0.0 2.6 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 CDJ47102.1 - 0.026 14.9 0.0 0.11 12.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 CDJ47102.1 - 0.033 14.1 0.0 0.033 14.1 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase TIP49 PF06068.13 CDJ47102.1 - 0.069 12.4 1.9 0.26 10.4 0.0 2.3 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_17 PF13207.6 CDJ47102.1 - 0.58 10.6 0.0 0.58 10.6 0.0 4.1 4 1 0 4 4 4 0 AAA domain AAA_28 PF13521.6 CDJ47102.1 - 1.7 8.9 0.0 1.7 8.9 0.0 5.7 3 2 1 4 4 3 0 AAA domain AAA_26 PF13500.6 CDJ47102.1 - 4.3 7.1 0.0 4.3 7.1 0.0 3.6 3 1 1 4 4 3 0 AAA domain DUF3273 PF11677.8 CDJ47103.1 - 3.8e-17 62.5 0.1 4.9e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) K_channel_TID PF07941.11 CDJ47103.1 - 0.0048 17.3 4.3 0.0089 16.5 4.3 1.4 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain Band_3_cyto PF07565.13 CDJ47104.1 - 0.85 9.4 24.3 0.13 12.1 2.4 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Vfa1 PF08432.10 CDJ47104.1 - 1 9.6 30.5 0.73 10.1 13.3 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 CDJ47104.1 - 1.2 7.8 40.7 0.44 9.3 18.9 2.0 2 0 0 2 2 2 0 Presenilin Apt1 PF10351.9 CDJ47104.1 - 1.7 7.4 35.3 1.4 7.6 15.9 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain UPF0564 PF10595.9 CDJ47104.1 - 2 7.4 42.2 7.9 5.4 42.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0564 NPR3 PF03666.13 CDJ47104.1 - 4.1 6.1 35.7 0.68 8.7 10.1 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 CDJ47104.1 - 4.6 7.2 29.8 2.9 7.8 11.7 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Hamartin PF04388.12 CDJ47104.1 - 6 5.4 35.9 8 5.0 35.9 1.1 1 0 0 1 1 1 0 Hamartin protein SID-1_RNA_chan PF13965.6 CDJ47104.1 - 6.4 5.1 13.0 0.13 10.7 0.7 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF3807 PF12720.7 CDJ47104.1 - 6.8 6.9 42.0 1.5 9.1 22.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Spt20 PF12090.8 CDJ47105.1 - 0.02 14.5 6.5 0.025 14.2 6.5 1.2 1 0 0 1 1 1 0 Spt20 family AF-4 PF05110.13 CDJ47105.1 - 0.34 9.0 7.6 0.42 8.6 7.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF1645 PF07816.11 CDJ47106.1 - 1.2 9.7 12.5 2.2 8.8 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ47106.1 - 2.2 7.8 37.2 0.063 12.9 11.7 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2232 PF09991.9 CDJ47107.1 - 0.018 14.2 7.0 0.023 13.9 7.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) eIF-3_zeta PF05091.12 CDJ47107.1 - 0.027 13.5 17.7 0.026 13.5 17.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.6 CDJ47107.1 - 0.033 12.6 3.9 0.034 12.6 3.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SprA-related PF12118.8 CDJ47107.1 - 0.067 12.3 51.4 0.088 11.9 51.4 1.1 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.13 CDJ47107.1 - 0.075 13.0 57.9 0.085 12.8 57.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.15 CDJ47107.1 - 0.088 11.7 11.3 0.097 11.6 11.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Connexin PF00029.19 CDJ47107.1 - 0.11 12.2 9.6 0.14 11.9 9.6 1.1 1 0 0 1 1 1 0 Connexin Lin-8 PF03353.15 CDJ47107.1 - 0.12 11.9 14.6 0.12 11.9 14.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NPR3 PF03666.13 CDJ47107.1 - 0.16 10.7 10.9 0.18 10.6 10.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIP PF07454.11 CDJ47107.1 - 0.17 11.3 16.6 0.21 11.0 16.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2828 PF11443.8 CDJ47107.1 - 0.17 9.9 12.2 0.17 9.9 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SMYLE_N PF18615.1 CDJ47107.1 - 0.19 11.2 15.5 0.23 11.0 15.5 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SLC12 PF03522.15 CDJ47107.1 - 0.21 10.6 13.2 0.2 10.6 13.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 HCO3_cotransp PF00955.21 CDJ47107.1 - 0.24 10.2 4.7 0.24 10.2 4.7 1.2 1 0 0 1 1 1 0 HCO3- transporter family DUF4569 PF15133.6 CDJ47107.1 - 0.27 10.9 13.6 0.27 10.9 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Rrn6 PF10214.9 CDJ47107.1 - 0.29 9.6 19.2 0.26 9.8 19.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CSG2 PF16965.5 CDJ47107.1 - 0.32 9.9 6.0 0.3 10.0 6.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Lipase_GDSL PF00657.22 CDJ47107.1 - 0.37 10.8 6.4 0.44 10.5 6.4 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DcuA_DcuB PF03605.14 CDJ47107.1 - 0.4 9.5 18.9 0.5 9.2 18.9 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Neur_chan_memb PF02932.16 CDJ47107.1 - 0.43 10.6 10.8 0.52 10.3 10.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DcuC PF03606.15 CDJ47107.1 - 0.46 8.9 12.1 0.57 8.6 12.1 1.3 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF1980 PF09323.10 CDJ47107.1 - 0.5 10.3 11.6 0.64 9.9 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Peptidase_S64 PF08192.11 CDJ47107.1 - 0.69 8.3 10.8 0.64 8.4 10.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 VIR_N PF15912.5 CDJ47107.1 - 0.99 9.0 8.3 1.1 8.8 8.3 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Presenilin PF01080.17 CDJ47107.1 - 1.2 7.9 25.1 1.4 7.6 25.1 1.2 1 0 0 1 1 1 0 Presenilin TFB6 PF17110.5 CDJ47107.1 - 1.2 8.9 8.2 1.5 8.6 8.2 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH EIF4E-T PF10477.9 CDJ47107.1 - 1.7 7.3 20.4 1.8 7.3 20.4 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Raftlin PF15250.6 CDJ47107.1 - 1.8 7.2 15.9 2.1 7.0 15.9 1.1 1 0 0 1 1 1 0 Raftlin Hamartin PF04388.12 CDJ47107.1 - 2 7.0 22.9 2.4 6.7 22.9 1.0 1 0 0 1 1 1 0 Hamartin protein LMBR1 PF04791.16 CDJ47107.1 - 2.3 7.0 6.6 2.1 7.2 6.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1387 PF07139.11 CDJ47107.1 - 2.8 7.6 17.2 3.2 7.4 17.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) O-antigen_lig PF13425.6 CDJ47107.1 - 3.3 6.4 6.4 3.9 6.1 6.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CCSAP PF15748.5 CDJ47107.1 - 4 7.5 24.7 5.7 7.0 24.7 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MAJIN PF15077.6 CDJ47107.1 - 4.3 7.1 12.1 4.8 6.9 12.1 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein AAA_23 PF13476.6 CDJ47107.1 - 4.6 7.7 17.4 5.6 7.4 17.4 1.1 1 0 0 1 1 1 0 AAA domain FAM176 PF14851.6 CDJ47107.1 - 4.6 6.9 10.2 7.3 6.2 10.2 1.3 1 0 0 1 1 1 0 FAM176 family AMP-binding PF00501.28 CDJ47107.1 - 5.3 5.5 12.5 6.6 5.2 12.5 1.2 1 0 0 1 1 1 0 AMP-binding enzyme Hid1 PF12722.7 CDJ47107.1 - 5.5 5.0 18.8 5.6 5.0 18.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NEMP PF10225.9 CDJ47107.1 - 5.6 6.5 6.6 7 6.2 6.6 1.2 1 0 0 1 1 1 0 NEMP family PIP5K PF01504.18 CDJ47107.1 - 6.5 5.9 15.1 8.9 5.4 15.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase PAT1 PF09770.9 CDJ47107.1 - 6.5 4.9 37.0 7.9 4.6 37.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAPS PF04499.15 CDJ47107.1 - 7.1 5.3 14.4 7.4 5.2 14.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MDM31_MDM32 PF08118.11 CDJ47107.1 - 7.4 5.1 11.9 10 4.6 11.9 1.3 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Cellulose_synt PF03552.14 CDJ47107.1 - 8.3 4.8 6.6 9.7 4.5 6.6 1.1 1 0 0 1 1 1 0 Cellulose synthase SR-25 PF10500.9 CDJ47108.1 - 0.006 16.2 87.5 0.087 12.4 31.1 3.2 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ47108.1 - 0.21 11.7 88.6 0.44 10.7 58.7 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated MAP7 PF05672.11 CDJ47108.1 - 8.8 6.0 95.0 6 6.5 74.8 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Utp14 PF04615.13 CDJ47109.1 - 0.00067 18.4 15.9 0.00067 18.4 15.9 1.7 2 1 0 2 2 2 1 Utp14 protein Spt20 PF12090.8 CDJ47109.1 - 0.0017 18.0 50.3 0.0031 17.1 16.0 2.7 2 0 0 2 2 2 1 Spt20 family EPL1 PF10513.9 CDJ47109.1 - 0.015 15.7 17.0 0.45 10.9 5.5 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like PIP5K PF01504.18 CDJ47109.1 - 0.025 13.8 7.7 0.21 10.8 1.0 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase SpoIIP PF07454.11 CDJ47109.1 - 0.089 12.2 19.1 0.34 10.3 6.2 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Activator_LAG-3 PF11498.8 CDJ47109.1 - 0.17 10.8 61.9 0.018 14.1 16.9 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Suf PF05843.14 CDJ47109.1 - 0.2 11.6 22.1 0.75 9.7 6.4 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 CDJ47109.1 - 0.21 10.5 23.8 0.43 9.5 4.6 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIEZO PF15917.5 CDJ47109.1 - 0.24 10.8 22.0 0.041 13.4 7.1 2.3 2 0 0 2 2 2 0 Piezo Connexin PF00029.19 CDJ47109.1 - 0.26 11.0 13.5 0.66 9.7 4.9 2.3 2 0 0 2 2 2 0 Connexin DUF5523 PF17661.1 CDJ47109.1 - 0.26 10.9 19.7 0.64 9.7 6.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5523) SID-1_RNA_chan PF13965.6 CDJ47109.1 - 0.29 9.5 0.9 2.9 6.2 0.0 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 EOS1 PF12326.8 CDJ47109.1 - 0.45 10.4 5.4 7.4 6.5 0.8 2.2 2 0 0 2 2 2 0 N-glycosylation protein HNOBA PF07701.14 CDJ47109.1 - 0.51 9.7 10.1 2.9 7.3 1.4 2.3 2 0 0 2 2 2 0 Heme NO binding associated DUF4770 PF15994.5 CDJ47109.1 - 0.52 10.5 19.7 0.89 9.8 5.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) CLN3 PF02487.17 CDJ47109.1 - 0.52 9.3 9.7 0.88 8.5 1.8 2.3 2 0 0 2 2 2 0 CLN3 protein FmiP_Thoc5 PF09766.9 CDJ47109.1 - 0.52 9.5 20.7 0.32 10.2 6.8 2.2 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 DUF913 PF06025.12 CDJ47109.1 - 0.54 9.2 10.6 1.2 8.0 1.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CSG2 PF16965.5 CDJ47109.1 - 0.55 9.1 3.2 1.9 7.3 0.1 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator MMU163 PF17119.5 CDJ47109.1 - 0.68 9.0 8.5 0.78 8.8 0.8 2.6 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Neur_chan_memb PF02932.16 CDJ47109.1 - 0.8 9.7 14.2 2.8 7.9 5.3 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MMR1 PF08505.10 CDJ47109.1 - 0.89 9.8 21.8 3.5 7.8 7.2 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Serinc PF03348.15 CDJ47109.1 - 0.92 8.4 7.1 2.5 6.9 0.9 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) SLC12 PF03522.15 CDJ47109.1 - 1.2 8.1 16.4 1.2 8.0 3.7 2.1 2 0 0 2 2 2 0 Solute carrier family 12 TERB2 PF15101.6 CDJ47109.1 - 1.4 8.9 25.4 4.2 7.4 9.9 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 FAM60A PF15396.6 CDJ47109.1 - 1.8 8.5 10.5 6.5 6.7 2.5 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Lin-8 PF03353.15 CDJ47109.1 - 2 7.9 20.2 1.9 8.0 7.4 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist V_ATPase_I PF01496.19 CDJ47109.1 - 2.3 6.0 19.2 0.85 7.5 7.3 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3807 PF12720.7 CDJ47109.1 - 2.5 8.3 32.0 0.85 9.9 8.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) Band_3_cyto PF07565.13 CDJ47109.1 - 3.1 7.5 16.3 5.1 6.8 5.4 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain UPF0560 PF10577.9 CDJ47109.1 - 3.1 6.2 30.8 3.3 6.1 12.8 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 YABBY PF04690.13 CDJ47109.1 - 3.4 8.2 14.8 4.7 7.8 3.5 3.2 3 0 0 3 3 3 0 YABBY protein Hydrolase PF00702.26 CDJ47109.1 - 4.2 7.6 29.3 13 6.0 26.6 2.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase LIM_bind PF01803.16 CDJ47109.1 - 4.6 6.7 16.3 3.9 6.9 3.3 2.4 2 0 0 2 2 2 0 LIM-domain binding protein DUF3371 PF11851.8 CDJ47109.1 - 5.9 8.0 21.2 5.1 8.2 5.3 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF3371) DUF4820 PF16091.5 CDJ47109.1 - 6.7 6.0 17.2 0.29 10.4 1.6 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4820) Rxt3 PF08642.10 CDJ47109.1 - 7 7.4 11.0 13 6.6 1.9 2.7 3 0 0 3 3 2 0 Histone deacetylation protein Rxt3 Peptidase_S49_N PF08496.10 CDJ47109.1 - 7.4 6.6 17.3 3.3 7.8 2.7 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Folliculin PF11704.8 CDJ47109.1 - 7.5 6.4 15.0 3.9 7.3 2.6 2.6 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Otopetrin PF03189.13 CDJ47109.1 - 7.7 5.2 7.0 8.8 5.0 1.7 2.1 2 0 0 2 2 2 0 Otopetrin MecA PF05389.12 CDJ47109.1 - 7.7 6.1 14.4 1.9 8.1 1.5 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) MDM10 PF12519.8 CDJ47109.1 - 8.5 5.1 14.0 1.2 8.0 1.9 2.1 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 RT_RNaseH PF17917.1 CDJ47111.1 - 5.2e-24 84.5 0.0 1.3e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ47111.1 - 5.1e-19 68.7 0.0 9.5e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ47111.1 - 8e-16 57.9 0.0 2.1e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase P22_AR_C PF10548.9 CDJ47111.1 - 0.064 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 P22AR C-terminal domain Ribosomal_L22 PF00237.19 CDJ47112.1 - 0.0099 16.1 1.1 0.013 15.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e BLF1 PF17752.1 CDJ47112.1 - 0.013 14.9 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Burkholderia lethal factor 1 MRFAP1 PF15155.6 CDJ47112.1 - 0.047 14.2 0.3 0.087 13.3 0.3 1.4 1 1 0 1 1 1 0 MORF4 family-associated protein1 Inhibitor_I34 PF10466.9 CDJ47112.1 - 0.12 13.0 0.9 0.21 12.2 0.2 1.8 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 Paf67 PF10255.9 CDJ47114.1 - 2.5e-125 418.7 1.0 2.5e-125 418.7 1.0 2.0 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 CDJ47114.1 - 0.044 13.9 4.4 0.051 13.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1440 PF07274.12 CDJ47114.1 - 0.19 12.1 0.9 0.31 11.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) MCU PF04678.13 CDJ47114.1 - 1.6 8.8 6.7 6.5 6.8 3.0 2.7 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Pkinase PF00069.25 CDJ47116.1 - 6.7e-05 22.4 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ47116.1 - 0.00012 21.4 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_trans_1_2 PF13524.6 CDJ47116.1 - 0.16 12.4 0.0 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Sec63 PF02889.16 CDJ47117.1 - 9.1e-123 408.4 0.0 2.8e-84 282.3 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CDJ47117.1 - 2.6e-42 144.5 1.8 6.7e-25 87.9 0.1 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CDJ47117.1 - 1e-32 112.6 1.0 3.4e-32 110.9 1.0 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 CDJ47117.1 - 5.6e-18 65.5 0.0 1.9e-13 50.8 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ47117.1 - 2.6e-13 50.3 0.0 2e-07 31.4 0.0 3.9 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ47117.1 - 0.00089 19.5 0.4 0.17 12.2 0.2 3.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 CDJ47117.1 - 0.12 12.8 0.0 0.61 10.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) YL1 PF05764.13 CDJ47117.1 - 8.8 6.4 17.6 0.025 14.7 6.6 2.0 1 1 0 2 2 2 0 YL1 nuclear protein Sec63 PF02889.16 CDJ47118.1 - 3.5e-19 69.0 0.0 3.9e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Sec63 Brl domain T4_baseplate PF12322.8 CDJ47118.1 - 0.009 15.5 0.3 0.039 13.4 0.1 1.8 2 0 0 2 2 2 1 T4 bacteriophage base plate protein LepA_C PF06421.12 CDJ47119.1 - 9.5e-23 80.4 0.0 1.7e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CDJ47119.1 - 9e-12 44.9 0.0 2.3e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 CDJ47119.1 - 0.0041 16.9 0.0 0.009 15.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain HrpB7 PF09486.10 CDJ47119.1 - 0.045 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) MnmE_helical PF12631.7 CDJ47119.1 - 0.057 13.6 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 MnmE helical domain EFG_II PF14492.6 CDJ47119.1 - 0.057 13.5 0.2 0.76 9.9 0.2 2.4 1 1 0 1 1 1 0 Elongation Factor G, domain II GTP_EFTU PF00009.27 CDJ47119.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain SET PF00856.28 CDJ47120.1 - 1.9e-12 47.9 0.1 1.4e-08 35.3 0.0 2.6 3 0 0 3 3 3 2 SET domain Clr5 PF14420.6 CDJ47120.1 - 0.043 14.1 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Clr5 domain CENP-F_leu_zip PF10473.9 CDJ47121.1 - 0.0046 17.0 6.5 0.0046 17.0 6.5 5.5 2 1 3 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MFS_1 PF07690.16 CDJ47122.1 - 3.1e-21 75.7 26.8 2.1e-09 36.8 2.6 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 CDJ47122.1 - 0.0031 16.4 1.3 0.065 12.1 0.0 2.3 1 1 1 2 2 2 2 MFS_1 like family DUF3446 PF11928.8 CDJ47123.1 - 0.00022 21.5 18.9 0.012 15.9 8.0 2.8 2 0 0 2 2 2 2 Early growth response N-terminal domain SR-25 PF10500.9 CDJ47123.1 - 0.0081 15.8 6.1 0.0081 15.8 6.1 4.4 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein 4_1_CTD PF05902.13 CDJ47123.1 - 4.7 7.3 6.8 0.26 11.4 1.0 2.0 2 0 0 2 2 2 0 4.1 protein C-terminal domain (CTD) DUF4058 PF13267.6 CDJ47124.1 - 0.013 15.0 9.2 0.015 14.7 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) DUF572 PF04502.13 CDJ47124.1 - 0.049 13.3 17.6 0.051 13.2 17.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) SRP-alpha_N PF04086.13 CDJ47124.1 - 0.083 12.8 18.9 0.092 12.7 18.9 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NARP1 PF12569.8 CDJ47124.1 - 0.14 11.1 18.9 0.15 10.9 18.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 CDJ47124.1 - 0.2 11.4 20.5 0.22 11.3 20.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1168 PF06658.12 CDJ47124.1 - 0.21 11.4 26.2 0.25 11.1 26.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) TFIIA PF03153.13 CDJ47124.1 - 0.28 11.1 46.3 0.3 11.1 46.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ47124.1 - 0.31 9.8 21.6 0.34 9.6 21.6 1.0 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 CDJ47124.1 - 0.32 11.1 19.7 0.37 10.9 19.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 CDJ47124.1 - 0.35 9.1 15.5 0.39 9.0 15.5 1.0 1 0 0 1 1 1 0 CDC45-like protein EOS1 PF12326.8 CDJ47124.1 - 0.38 10.7 12.6 0.45 10.4 12.6 1.1 1 0 0 1 1 1 0 N-glycosylation protein MID_MedPIWI PF18296.1 CDJ47124.1 - 0.42 10.4 18.8 0.46 10.2 18.8 1.0 1 0 0 1 1 1 0 MID domain of medPIWI ALMT PF11744.8 CDJ47124.1 - 0.49 9.2 17.1 0.52 9.1 17.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter GPCR_chapero_1 PF11904.8 CDJ47124.1 - 0.54 9.7 13.9 0.59 9.5 13.9 1.0 1 0 0 1 1 1 0 GPCR-chaperone CPSF100_C PF13299.6 CDJ47124.1 - 0.55 10.4 13.6 0.73 10.0 13.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 CDJ47124.1 - 0.59 9.5 19.8 0.71 9.3 19.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) V_ATPase_I PF01496.19 CDJ47124.1 - 0.63 7.9 20.8 0.67 7.8 20.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.17 CDJ47124.1 - 0.67 10.1 18.8 0.77 9.9 18.8 1.1 1 0 0 1 1 1 0 DDHD domain CCDC53 PF10152.9 CDJ47124.1 - 0.69 10.3 17.3 0.68 10.3 17.3 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Baculo_PP31 PF05311.11 CDJ47124.1 - 0.7 9.3 18.2 0.91 9.0 18.2 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF2347 PF09804.9 CDJ47124.1 - 0.72 9.4 13.4 0.9 9.1 13.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Asp-B-Hydro_N PF05279.11 CDJ47124.1 - 0.72 9.9 15.6 0.79 9.7 15.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SLC12 PF03522.15 CDJ47124.1 - 0.87 8.5 21.7 0.91 8.5 21.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 CDJ47124.1 - 0.88 8.5 10.8 0.96 8.4 10.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PRC2_HTH_1 PF18118.1 CDJ47124.1 - 0.91 10.4 14.2 1.4 9.8 14.2 1.3 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain LIM_bind PF01803.16 CDJ47124.1 - 0.93 9.0 20.3 1.3 8.5 20.3 1.1 1 0 0 1 1 1 0 LIM-domain binding protein SKA1 PF07160.12 CDJ47124.1 - 0.94 9.3 23.1 1 9.2 23.1 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 AAA_11 PF13086.6 CDJ47124.1 - 0.95 9.2 21.9 1 9.1 21.9 1.0 1 0 0 1 1 1 0 AAA domain GNAT_acetyltr_2 PF13718.6 CDJ47124.1 - 1 8.7 12.9 1.3 8.3 12.9 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 PTPlike_phytase PF14566.6 CDJ47124.1 - 1.1 9.4 13.8 1.4 9.0 13.8 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate Ctr PF04145.15 CDJ47124.1 - 1.1 9.9 14.4 1.3 9.6 14.4 1.1 1 0 0 1 1 1 0 Ctr copper transporter family FAM60A PF15396.6 CDJ47124.1 - 1.2 9.1 17.0 1.3 8.9 17.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4746 PF15928.5 CDJ47124.1 - 1.4 8.3 14.6 1.5 8.2 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Serinc PF03348.15 CDJ47124.1 - 1.4 7.7 11.8 1.7 7.5 11.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) YABBY PF04690.13 CDJ47124.1 - 1.5 9.4 16.1 1.6 9.2 16.1 1.2 1 0 0 1 1 1 0 YABBY protein Hydin_ADK PF17213.3 CDJ47124.1 - 1.5 9.1 15.9 1.7 8.9 15.9 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Mgr1 PF08602.10 CDJ47124.1 - 1.6 7.5 12.3 1.8 7.3 12.3 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Exonuc_VII_L PF02601.15 CDJ47124.1 - 1.6 8.2 26.5 1.8 8.1 26.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Folliculin PF11704.8 CDJ47124.1 - 1.7 8.5 16.2 2.1 8.2 16.2 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport PAT1 PF09770.9 CDJ47124.1 - 1.8 6.7 33.4 2 6.6 33.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hox9_act PF04617.13 CDJ47124.1 - 1.9 9.2 11.8 2.2 9.0 11.8 1.0 1 0 0 1 1 1 0 Hox9 activation region RP-C_C PF11800.8 CDJ47124.1 - 2.1 8.4 18.7 2.6 8.1 18.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Hid1 PF12722.7 CDJ47124.1 - 2.3 6.3 17.2 2.4 6.2 17.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Phage_GPO PF05929.11 CDJ47124.1 - 2.5 7.7 20.3 2.7 7.5 20.3 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Tim54 PF11711.8 CDJ47124.1 - 3.4 6.4 17.7 3.8 6.2 17.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3_zeta PF05091.12 CDJ47124.1 - 3.4 6.5 26.5 3.9 6.4 26.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2828 PF11443.8 CDJ47124.1 - 3.4 5.6 22.8 4 5.4 22.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DAG_kinase_N PF14513.6 CDJ47124.1 - 3.8 7.7 25.1 4.8 7.4 25.1 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus BPL_N PF09825.9 CDJ47124.1 - 4 6.4 13.8 4.2 6.4 13.8 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal LicD PF04991.13 CDJ47124.1 - 4.1 7.5 11.1 4.5 7.3 11.1 1.2 1 0 0 1 1 1 0 LicD family CLN3 PF02487.17 CDJ47124.1 - 4.5 6.2 15.5 4.9 6.1 15.5 1.1 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 CDJ47124.1 - 4.5 7.2 17.7 4.8 7.2 17.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM176 PF14851.6 CDJ47124.1 - 4.7 6.9 11.4 6.6 6.4 11.4 1.4 1 0 0 1 1 1 0 FAM176 family DUF853 PF05872.12 CDJ47124.1 - 5.1 5.6 15.1 6.1 5.3 15.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) BCIP PF13862.6 CDJ47124.1 - 5.3 6.8 18.4 7.1 6.3 18.4 1.2 1 0 0 1 1 1 0 p21-C-terminal region-binding protein Plasmodium_Vir PF05795.11 CDJ47124.1 - 5.4 6.3 14.0 6.4 6.1 14.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1764 PF08576.10 CDJ47124.1 - 5.7 7.9 21.1 9.3 7.2 21.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Ureide_permease PF07168.11 CDJ47124.1 - 5.8 5.6 9.5 7.6 5.2 9.5 1.3 1 0 0 1 1 1 0 Ureide permease Band_3_cyto PF07565.13 CDJ47124.1 - 6.7 6.4 20.6 8.2 6.1 20.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Connexin PF00029.19 CDJ47124.1 - 6.7 6.4 17.5 8.6 6.0 17.5 1.2 1 0 0 1 1 1 0 Connexin Membralin PF09746.9 CDJ47124.1 - 6.8 5.6 14.5 7.4 5.5 14.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF5003 PF16394.5 CDJ47124.1 - 6.9 5.7 10.7 7.5 5.6 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) AUX_IAA PF02309.16 CDJ47124.1 - 7.4 6.4 15.8 8.7 6.1 15.8 1.1 1 0 0 1 1 1 0 AUX/IAA family Tweety PF04906.13 CDJ47124.1 - 7.7 5.1 14.1 8.5 4.9 14.1 1.1 1 0 0 1 1 1 0 Tweety Het-C PF07217.11 CDJ47124.1 - 7.8 4.9 16.5 8.2 4.8 16.5 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C MDM31_MDM32 PF08118.11 CDJ47124.1 - 8.5 4.9 17.5 10 4.6 17.5 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins RBP_receptor PF14752.6 CDJ47124.1 - 8.6 4.8 14.1 13 4.2 14.1 1.3 1 0 0 1 1 1 0 Retinol binding protein receptor Utp14 PF04615.13 CDJ47128.1 - 0.094 11.3 34.3 0.13 10.9 34.3 1.2 1 0 0 1 1 1 0 Utp14 protein SOG2 PF10428.9 CDJ47128.1 - 0.13 11.4 25.6 0.16 11.1 25.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.13 CDJ47128.1 - 4.3 6.9 32.0 6.1 6.4 32.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) VIR_N PF15912.5 CDJ47130.1 - 0.049 13.2 8.0 0.06 12.9 8.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4551 PF15087.6 CDJ47130.1 - 0.45 9.3 19.6 0.54 9.0 19.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hamartin PF04388.12 CDJ47130.1 - 0.47 9.1 22.9 0.56 8.8 22.9 1.0 1 0 0 1 1 1 0 Hamartin protein PAT1 PF09770.9 CDJ47130.1 - 0.59 8.3 42.8 0.65 8.2 42.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 CDJ47130.1 - 0.87 8.5 17.6 1 8.3 17.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Exosortase_EpsH PF09721.10 CDJ47130.1 - 1.1 8.7 5.0 0.59 9.6 1.2 1.9 2 0 0 2 2 2 0 Transmembrane exosortase (Exosortase_EpsH) LMBR1 PF04791.16 CDJ47130.1 - 1.3 7.8 3.9 1.3 7.8 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Med15 PF09606.10 CDJ47130.1 - 1.6 7.3 62.2 2 7.0 62.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ALMT PF11744.8 CDJ47130.1 - 1.7 7.4 13.1 2.1 7.1 13.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Lin-8 PF03353.15 CDJ47130.1 - 2 7.9 28.5 2.7 7.5 28.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Smg8_Smg9 PF10220.9 CDJ47130.1 - 9.3 4.4 18.4 9.9 4.3 18.4 1.3 1 0 0 1 1 1 0 Smg8_Smg9 YfhO PF09586.10 CDJ47130.1 - 9.7 4.3 10.5 10 4.2 10.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SWIRM-assoc_1 PF16495.5 CDJ47131.1 - 4.7e-09 36.1 11.0 4.7e-09 36.1 11.0 6.9 10 0 0 10 10 10 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 CDJ47131.1 - 1.7e-07 31.3 0.1 4.8e-06 26.7 0.0 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain DUF1543 PF07566.12 CDJ47131.1 - 0.0014 18.3 3.0 0.8 9.5 0.1 3.6 1 1 2 3 3 3 2 Domain of Unknown Function (DUF1543) Myb_DNA-bind_6 PF13921.6 CDJ47131.1 - 0.0018 18.5 0.0 0.0044 17.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Spt20 PF12090.8 CDJ47131.1 - 0.27 10.8 36.0 0.21 11.2 2.2 2.9 3 0 0 3 3 3 0 Spt20 family DUF2722 PF10846.8 CDJ47131.1 - 2.7 6.8 26.0 0.35 9.8 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Aminotran_5 PF00266.19 CDJ47133.1 - 5.8e-38 130.8 7.0 2.1e-34 119.1 0.6 2.9 2 1 0 3 3 3 2 Aminotransferase class-V FapA PF03961.13 CDJ47133.1 - 0.00083 18.1 14.3 0.00083 18.1 14.3 2.0 2 0 0 2 2 2 1 Flagellar Assembly Protein A DUF1676 PF07898.13 CDJ47133.1 - 0.0041 17.2 0.7 0.0041 17.2 0.7 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1676) TMEM154 PF15102.6 CDJ47133.1 - 0.0096 15.8 0.3 1.1 9.1 0.0 2.7 3 0 0 3 3 3 1 TMEM154 protein family DUF898 PF05987.13 CDJ47133.1 - 0.029 13.5 5.1 0.13 11.3 2.7 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF4220 PF13968.6 CDJ47133.1 - 0.14 11.5 7.1 1.2 8.5 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) Adaptin_binding PF10199.9 CDJ47133.1 - 0.5 11.0 22.0 0.71 10.5 16.8 2.4 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 AAA_11 PF13086.6 CDJ47133.1 - 0.65 9.7 20.8 0.12 12.2 12.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3801 PF12687.7 CDJ47133.1 - 1.1 9.3 17.7 0.026 14.6 8.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Utp11 PF03998.13 CDJ47133.1 - 1.9 8.4 25.7 0.25 11.3 16.6 2.2 2 0 0 2 2 2 0 Utp11 protein Allexi_40kDa PF05549.11 CDJ47133.1 - 2.2 7.7 18.6 0.33 10.4 9.6 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein Phage_GPO PF05929.11 CDJ47133.1 - 3.9 7.0 28.4 0.27 10.8 17.8 2.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Paramecium_SA PF01508.16 CDJ47133.1 - 6.2 7.3 9.8 26 5.3 9.8 2.1 1 1 0 1 1 1 0 Paramecium surface antigen domain Macoilin PF09726.9 CDJ47133.1 - 6.3 5.2 27.9 1.7 7.1 12.1 2.3 2 0 0 2 2 2 0 Macoilin family Cob_adeno_trans PF01923.18 CDJ47133.1 - 9 6.4 12.9 0.66 10.1 5.8 2.3 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF4577 PF15145.6 CDJ47134.1 - 0.034 14.2 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) CCB1 PF12046.8 CDJ47134.1 - 0.092 12.1 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B Peptidase_M48 PF01435.18 CDJ47135.1 - 5.6e-41 140.5 0.0 1.6e-40 139.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M48_N PF16491.5 CDJ47135.1 - 6.9e-40 136.9 1.5 9.7e-38 129.9 0.2 2.7 2 1 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Stevor PF17410.2 CDJ47136.1 - 0.068 12.7 0.6 31 4.0 0.0 3.8 3 0 0 3 3 3 0 Subtelomeric Variable Open Reading frame AMMECR1 PF01871.17 CDJ47136.1 - 1.8 8.1 6.2 0.16 11.6 0.3 2.3 2 0 0 2 2 2 0 AMMECR1 TFIIA PF03153.13 CDJ47137.1 - 0.022 14.8 11.0 0.025 14.6 11.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ47137.1 - 0.023 14.8 12.0 0.05 13.7 12.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 CDJ47137.1 - 0.033 15.2 2.2 0.046 14.7 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ47137.1 - 0.042 13.5 12.1 0.053 13.1 12.1 1.2 1 0 0 1 1 1 0 Spt20 family DUF2235 PF09994.9 CDJ47137.1 - 0.087 12.2 1.6 0.11 11.8 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Med3 PF11593.8 CDJ47137.1 - 0.1 11.7 9.3 0.14 11.3 9.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2722 PF10846.8 CDJ47137.1 - 0.28 10.1 11.9 0.34 9.8 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DivIC PF04977.15 CDJ47137.1 - 0.38 10.5 10.3 0.85 9.4 10.3 1.6 1 0 0 1 1 1 0 Septum formation initiator Peptidase_S64 PF08192.11 CDJ47138.1 - 0.13 10.7 4.4 0.16 10.4 4.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 eIF-5a PF01287.20 CDJ47139.1 - 5.3e-26 90.5 0.1 7.7e-26 90.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CDJ47139.1 - 0.0014 18.6 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Connexin PF00029.19 CDJ47140.1 - 0.0052 16.6 6.2 0.0052 16.6 6.2 2.1 2 0 0 2 2 2 1 Connexin RNA_pol_Rpc4 PF05132.14 CDJ47140.1 - 0.0083 16.6 10.2 0.0083 16.6 10.2 2.2 2 0 0 2 2 2 1 RNA polymerase III RPC4 SID-1_RNA_chan PF13965.6 CDJ47140.1 - 0.13 10.7 10.3 0.16 10.3 10.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Trypan_PARP PF05887.11 CDJ47140.1 - 0.14 12.1 1.8 0.23 11.4 1.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF5427 PF10310.9 CDJ47140.1 - 0.58 9.1 30.7 0.87 8.5 30.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Ctr PF04145.15 CDJ47140.1 - 0.8 10.3 16.9 0.036 14.7 6.0 2.1 2 0 0 2 2 2 0 Ctr copper transporter family CAC1F_C PF16885.5 CDJ47140.1 - 0.87 9.2 19.6 1 9.0 19.6 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term HCO3_cotransp PF00955.21 CDJ47140.1 - 1.8 7.3 9.5 0.55 9.0 7.0 1.4 1 1 0 1 1 1 0 HCO3- transporter family SAPS PF04499.15 CDJ47140.1 - 2.5 6.8 20.2 3 6.5 20.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pinin_SDK_memA PF04696.13 CDJ47140.1 - 2.5 8.2 51.7 0.14 12.2 29.6 2.4 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Peroxin-3 PF04882.12 CDJ47140.1 - 8.9 5.2 27.8 11 4.9 27.8 1.1 1 0 0 1 1 1 0 Peroxin-3 DUF3984 PF13136.6 CDJ47140.1 - 9.1 5.6 23.1 1 8.7 11.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) Aminotran_5 PF00266.19 CDJ47141.1 - 1.1e-95 320.8 0.1 2.4e-95 319.7 0.0 1.5 1 1 1 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CDJ47141.1 - 4.4e-09 36.0 0.0 4.4e-09 36.0 0.0 2.1 3 0 0 3 3 3 1 Aminotransferase class I and II SUIM_assoc PF16619.5 CDJ47141.1 - 0.01 15.9 2.4 0.01 15.9 2.4 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ47141.1 - 0.044 13.4 5.4 0.49 10.0 4.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ASFV_J13L PF05568.11 CDJ47142.1 - 0.89 9.3 9.5 1 9.1 9.5 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Methyltransf_34 PF11312.8 CDJ47142.1 - 1.3 8.2 8.3 8.9 5.5 8.3 1.9 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase DUF4179 PF13786.6 CDJ47142.1 - 1.6 9.3 4.1 4.1 7.9 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) MAM33 PF02330.16 CDJ47143.1 - 0.00031 20.8 3.6 0.00031 20.8 3.6 1.9 2 0 0 2 2 2 1 Mitochondrial glycoprotein Methyltransf_34 PF11312.8 CDJ47143.1 - 0.00085 18.7 1.5 0.0011 18.3 1.5 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Cauli_DNA-bind PF03310.13 CDJ47143.1 - 0.0027 17.8 1.8 0.0035 17.4 1.8 1.1 1 0 0 1 1 1 1 Caulimovirus DNA-binding protein RskA PF10099.9 CDJ47143.1 - 0.0056 17.0 2.3 0.0067 16.8 2.3 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Hom_end_hint PF05203.16 CDJ47143.1 - 0.023 14.6 0.6 0.03 14.3 0.6 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint DUF2175 PF09943.9 CDJ47143.1 - 0.18 12.1 3.8 0.26 11.6 3.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) SpoU_sub_bind PF08032.12 CDJ47143.1 - 0.54 10.6 3.9 0.17 12.2 0.6 1.7 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Roughex PF06020.11 CDJ47143.1 - 0.56 9.2 4.2 0.73 8.9 4.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein IMUP PF15761.5 CDJ47143.1 - 2.8 8.7 11.8 7 7.4 0.5 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein RskA PF10099.9 CDJ47144.1 - 0.00098 19.5 6.2 0.00098 19.5 6.2 3.3 1 1 1 2 2 1 1 Anti-sigma-K factor rskA MMR1 PF08505.10 CDJ47144.1 - 0.007 16.7 8.5 0.01 16.2 8.5 1.2 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein Spem1 PF15670.5 CDJ47144.1 - 0.045 13.3 5.0 0.064 12.8 5.0 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Connexin PF00029.19 CDJ47144.1 - 0.11 12.3 0.4 0.13 12.1 0.4 1.2 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 CDJ47144.1 - 0.14 10.5 0.5 0.15 10.4 0.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Rrn6 PF10214.9 CDJ47144.1 - 0.25 9.8 10.9 0.31 9.5 10.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Spt20 PF12090.8 CDJ47144.1 - 0.34 10.5 23.1 0.064 12.9 19.4 1.6 2 0 0 2 2 2 0 Spt20 family Wzy_C PF04932.15 CDJ47144.1 - 0.34 10.5 1.4 0.97 9.1 1.2 1.8 2 0 0 2 2 2 0 O-Antigen ligase GREB1 PF15782.5 CDJ47144.1 - 1.1 6.3 8.4 1.1 6.3 8.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S49_N PF08496.10 CDJ47144.1 - 1.3 9.1 8.1 2.4 8.2 3.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Hid1 PF12722.7 CDJ47144.1 - 1.6 6.8 7.4 1.7 6.7 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CNDH2_C PF16858.5 CDJ47144.1 - 3.3 7.5 13.1 4.2 7.2 12.7 1.2 1 1 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2722 PF10846.8 CDJ47144.1 - 3.7 6.4 22.8 7.8 5.3 22.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SWI-SNF_Ssr4 PF08549.10 CDJ47144.1 - 4 6.0 19.6 4.7 5.7 19.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Miga PF10265.9 CDJ47144.1 - 6.7 5.6 10.0 8 5.3 10.0 1.2 1 0 0 1 1 1 0 Mitoguardin RLL PF10036.9 CDJ47144.1 - 8.2 6.2 14.6 17 5.2 14.6 1.5 1 1 0 1 1 1 0 RNA transcription, translation and transport factor protein Ndc1_Nup PF09531.10 CDJ47144.1 - 9 4.9 10.2 9.6 4.8 10.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Exonuc_VII_L PF02601.15 CDJ47145.1 - 0.098 12.2 28.3 0.13 11.8 28.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MRP-S27 PF10037.9 CDJ47145.1 - 0.28 10.0 26.5 0.33 9.8 26.5 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF572 PF04502.13 CDJ47145.1 - 0.4 10.2 18.1 0.54 9.8 18.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) eIF-3_zeta PF05091.12 CDJ47145.1 - 0.55 9.2 27.8 0.76 8.7 27.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ47145.1 - 1.5 7.0 41.1 1.9 6.7 41.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ47145.1 - 1.8 8.5 15.4 2.3 8.2 15.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HI0933_like PF03486.14 CDJ47145.1 - 3.9 6.1 18.7 7 5.2 18.7 1.4 1 0 0 1 1 1 0 HI0933-like protein Lin-8 PF03353.15 CDJ47145.1 - 7.1 6.1 27.4 9.2 5.7 27.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Caldesmon PF02029.15 CDJ47145.1 - 9.8 4.8 29.6 13 4.5 29.6 1.1 1 0 0 1 1 1 0 Caldesmon SUIM_assoc PF16619.5 CDJ47146.1 - 1.1 9.4 9.4 14 5.8 0.2 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 IMUP PF15761.5 CDJ47146.1 - 2.6 8.8 8.1 6.1 7.6 8.1 1.8 1 1 0 1 1 1 0 Immortalisation up-regulated protein Ribosomal_60s PF00428.19 CDJ47146.1 - 5.2 7.7 20.3 2.1 9.0 9.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Atrophin-1 PF03154.15 CDJ47146.1 - 8 4.6 10.4 9.7 4.3 10.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family PAP1 PF08601.10 CDJ47153.1 - 8.5 6.0 11.3 12 5.4 11.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Fumble PF03630.14 CDJ47154.1 - 3.5e-58 197.4 0.0 1.8e-49 168.7 0.0 3.2 3 0 0 3 3 3 3 Fumble DUF1635 PF07795.11 CDJ47154.1 - 0.008 16.1 1.1 0.008 16.1 1.1 3.2 5 0 0 5 5 5 1 Protein of unknown function (DUF1635) Chorion_2 PF03964.15 CDJ47154.1 - 0.019 15.8 14.6 0.019 15.8 14.6 6.0 6 1 0 7 7 7 0 Chorion family 2 SARAF PF06682.12 CDJ47154.1 - 0.064 12.9 16.3 0.17 11.5 16.3 1.6 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TAXi_C PF14541.6 CDJ47154.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Apt1 PF10351.9 CDJ47154.1 - 0.18 10.6 3.1 0.29 9.9 3.1 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ47154.1 - 0.44 9.1 9.4 0.85 8.1 9.4 1.5 1 0 0 1 1 1 0 Macoilin family Peroxin-3 PF04882.12 CDJ47154.1 - 6.8 5.6 9.1 16 4.4 9.1 1.6 1 0 0 1 1 1 0 Peroxin-3 CDC45 PF02724.14 CDJ47156.1 - 0.046 12.0 17.4 0.051 11.9 17.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Bac_luciferase PF00296.20 CDJ47156.1 - 0.12 11.7 16.3 0.16 11.4 16.3 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF572 PF04502.13 CDJ47156.1 - 0.18 11.4 22.6 0.21 11.2 22.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SprA-related PF12118.8 CDJ47156.1 - 0.22 10.6 45.6 0.33 10.1 45.6 1.2 1 0 0 1 1 1 0 SprA-related family SID-1_RNA_chan PF13965.6 CDJ47156.1 - 0.25 9.7 6.1 0.26 9.7 6.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 CDJ47156.1 - 0.26 9.5 40.8 0.29 9.4 40.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hamartin PF04388.12 CDJ47156.1 - 0.43 9.2 20.2 0.44 9.1 20.2 1.1 1 0 0 1 1 1 0 Hamartin protein Exonuc_VII_L PF02601.15 CDJ47156.1 - 0.87 9.1 30.2 1.1 8.8 30.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.8 CDJ47156.1 - 0.89 8.3 17.6 1 8.1 17.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SAPS PF04499.15 CDJ47156.1 - 0.96 8.2 16.5 1 8.1 16.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GET2 PF08690.10 CDJ47156.1 - 1.1 8.9 26.1 1.3 8.6 26.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 RIFIN PF02009.16 CDJ47156.1 - 1.9 8.3 21.8 2.6 7.9 21.8 1.1 1 0 0 1 1 1 0 Rifin GREB1 PF15782.5 CDJ47156.1 - 2 5.4 27.6 2.1 5.3 27.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer V_ATPase_I PF01496.19 CDJ47156.1 - 2.5 5.9 22.1 3 5.6 22.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF-3_zeta PF05091.12 CDJ47156.1 - 2.7 6.9 33.4 3.1 6.7 33.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ47156.1 - 2.9 6.8 25.6 3.5 6.6 25.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 LMBR1 PF04791.16 CDJ47156.1 - 3.1 6.6 14.3 2.7 6.8 14.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MgsA_C PF12002.8 CDJ47156.1 - 3.7 7.5 21.3 5.2 7.0 21.3 1.1 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal VIR_N PF15912.5 CDJ47156.1 - 4 6.9 14.5 5.6 6.5 14.5 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal CDC27 PF09507.10 CDJ47156.1 - 4.2 6.6 31.5 5.1 6.4 31.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Zip PF02535.22 CDJ47156.1 - 5.8 6.0 12.5 7.7 5.6 12.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PA26 PF04636.13 CDJ47156.1 - 6.4 5.6 21.4 9.9 4.9 21.4 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) LAP1C PF05609.12 CDJ47156.1 - 7 5.6 28.7 7.4 5.5 28.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) AMP-binding PF00501.28 CDJ47156.1 - 7.8 5.0 8.6 10 4.6 8.6 1.2 1 0 0 1 1 1 0 AMP-binding enzyme Lin-8 PF03353.15 CDJ47156.1 - 8.1 5.9 31.1 11 5.4 31.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GDPD PF03009.17 CDJ47157.1 - 7.7e-07 29.1 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CobT PF06213.12 CDJ47158.1 - 0.0072 15.8 44.4 0.038 13.4 29.8 2.2 2 0 0 2 2 2 2 Cobalamin biosynthesis protein CobT AF-4 PF05110.13 CDJ47158.1 - 0.13 10.3 41.7 0.18 9.9 41.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein VIR_N PF15912.5 CDJ47158.1 - 0.18 11.3 14.5 0.094 12.3 6.9 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal Caldesmon PF02029.15 CDJ47158.1 - 0.19 10.5 34.2 0.22 10.2 34.2 1.1 1 0 0 1 1 1 0 Caldesmon PAT1 PF09770.9 CDJ47158.1 - 0.23 9.7 64.4 0.32 9.2 64.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Na_trans_assoc PF06512.13 CDJ47158.1 - 0.31 11.3 19.1 0.43 10.8 19.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2052 PF09747.9 CDJ47158.1 - 0.32 11.1 36.6 1.8 8.6 4.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SPX PF03105.19 CDJ47158.1 - 0.32 10.9 24.1 0.49 10.2 24.1 1.3 1 0 0 1 1 1 0 SPX domain DUF726 PF05277.12 CDJ47158.1 - 0.34 9.8 4.7 0.44 9.4 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) SARAF PF06682.12 CDJ47158.1 - 0.37 10.4 34.2 0.034 13.8 17.3 2.1 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SpoIIP PF07454.11 CDJ47158.1 - 0.53 9.7 33.7 2 7.8 21.8 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SART-1 PF03343.13 CDJ47158.1 - 0.71 8.3 37.2 0.13 10.8 24.9 2.1 2 0 0 2 2 2 0 SART-1 family ArsP_1 PF03773.13 CDJ47158.1 - 1.2 8.2 10.6 2.9 7.0 10.6 1.8 1 1 0 1 1 1 0 Predicted permease Hid1 PF12722.7 CDJ47158.1 - 1.6 6.8 33.1 2 6.5 33.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_M56 PF05569.11 CDJ47158.1 - 2.6 7.2 26.8 0.18 11.0 12.1 2.1 1 1 1 2 2 2 0 BlaR1 peptidase M56 Ndc1_Nup PF09531.10 CDJ47158.1 - 4.6 5.8 30.3 5.3 5.6 30.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.15 CDJ47159.1 - 0.041 13.4 11.6 0.048 13.2 11.6 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4667 PF15700.5 CDJ47159.1 - 0.062 13.4 12.5 0.071 13.2 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) DUF1645 PF07816.11 CDJ47159.1 - 0.16 12.5 11.4 0.18 12.4 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) TFIIA PF03153.13 CDJ47159.1 - 0.65 9.9 20.7 0.77 9.7 20.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PARM PF17061.5 CDJ47159.1 - 0.95 9.5 14.5 1 9.4 14.5 1.0 1 0 0 1 1 1 0 PARM Apt1 PF10351.9 CDJ47159.1 - 1 8.1 10.5 1.2 7.9 10.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ47159.1 - 3.6 6.3 9.8 4 6.1 9.8 1.1 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ47160.1 - 0.001 18.7 15.9 0.0014 18.3 15.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ47160.1 - 0.019 14.9 2.5 0.019 14.9 2.5 1.1 1 0 0 1 1 1 0 SPX domain PGI PF00342.19 CDJ47160.1 - 0.037 12.6 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoglucose isomerase Presenilin PF01080.17 CDJ47160.1 - 0.078 11.7 0.0 0.078 11.7 0.0 1.1 1 0 0 1 1 1 0 Presenilin DUF755 PF05501.11 CDJ47160.1 - 0.12 12.6 14.4 0.16 12.2 14.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Apt1 PF10351.9 CDJ47160.1 - 0.33 9.8 2.6 0.39 9.5 2.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC106 PF15794.5 CDJ47160.1 - 0.56 9.9 3.2 0.69 9.6 3.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 MDFI PF15316.6 CDJ47160.1 - 0.7 10.0 4.5 1 9.5 4.5 1.2 1 0 0 1 1 1 0 MyoD family inhibitor AF-4 PF05110.13 CDJ47160.1 - 0.97 7.4 19.8 1.2 7.1 19.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4228 PF14009.6 CDJ47160.1 - 1.4 9.3 8.8 0.094 13.1 3.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Tis11B_N PF04553.12 CDJ47160.1 - 4.9 7.7 9.1 74 3.9 8.3 2.2 1 1 1 2 2 2 0 Tis11B like protein, N terminus DUF4692 PF15763.5 CDJ47160.1 - 9 6.7 9.7 13 6.2 9.7 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) RAP1 PF07218.11 CDJ47160.1 - 9 4.4 11.0 11 4.1 11.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Fer2 PF00111.27 CDJ47161.1 - 1.4e-09 37.7 5.5 1.4e-09 37.7 5.5 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Pex14_N PF04695.13 CDJ47162.1 - 0.00081 20.1 5.8 0.00081 20.1 5.8 7.6 4 2 1 6 6 6 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ47162.1 - 0.002 17.8 7.9 0.002 17.8 7.9 6.8 4 2 1 5 5 5 2 Spt20 family RIC3 PF15361.6 CDJ47162.1 - 0.014 15.8 0.0 0.014 15.8 0.0 5.3 4 2 0 4 4 4 0 Resistance to inhibitors of cholinesterase homologue 3 Frizzled PF01534.17 CDJ47162.1 - 1.4 7.8 4.4 0.71 8.9 0.2 2.5 3 0 0 3 3 3 0 Frizzled/Smoothened family membrane region DNA_pol_phi PF04931.13 CDJ47163.1 - 2.2 6.3 22.5 4.6 5.2 22.5 1.6 1 0 0 1 1 1 0 DNA polymerase phi HEAT PF02985.22 CDJ47165.1 - 3.5e-06 26.8 4.6 0.33 11.3 0.0 5.4 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.23 CDJ47165.1 - 7.6e-05 22.6 3.7 0.42 10.7 0.1 3.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CDJ47165.1 - 8.8e-05 22.9 0.2 8.8e-05 22.9 0.2 7.9 6 3 1 7 7 7 3 HEAT-like repeat GSAP-16 PF14959.6 CDJ47165.1 - 0.0045 16.9 0.1 0.021 14.7 0.1 2.2 1 0 0 1 1 1 1 gamma-Secretase-activating protein C-term UME PF08064.13 CDJ47165.1 - 0.0047 16.8 0.0 0.21 11.5 0.0 3.4 3 0 0 3 3 3 1 UME (NUC010) domain NACHT_N PF17100.5 CDJ47165.1 - 1.4 8.8 11.7 0.063 13.1 2.5 2.6 2 1 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase Cadherin_C_2 PF16492.5 CDJ47165.1 - 2.6 8.8 4.2 16 6.3 0.0 2.9 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Conotoxin PF02950.17 CDJ47165.1 - 4.2 8.5 8.6 5 8.2 1.1 3.3 2 0 0 2 2 2 0 Conotoxin Hydin_ADK PF17213.3 CDJ47165.1 - 6.2 7.0 18.2 4.1 7.6 3.3 4.0 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain UVR PF02151.19 CDJ47166.1 - 0.035 13.8 4.1 0.11 12.2 4.1 2.0 1 0 0 1 1 1 0 UvrB/uvrC motif DUF2547 PF10818.8 CDJ47166.1 - 0.63 11.0 5.4 0.51 11.3 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) DUF3138 PF11336.8 CDJ47166.1 - 1.3 7.5 5.9 1.8 7.1 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PIP5K PF01504.18 CDJ47168.1 - 0.051 12.8 7.0 0.059 12.6 7.0 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase ANAPC_CDC26 PF10471.9 CDJ47168.1 - 0.052 14.4 38.7 0.85 10.5 15.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 ORC_WH_C PF18137.1 CDJ47168.1 - 0.052 13.6 7.5 0.071 13.2 7.5 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Presenilin PF01080.17 CDJ47168.1 - 0.059 12.1 12.0 0.068 11.9 12.0 1.1 1 0 0 1 1 1 0 Presenilin Rrp40_N PF18311.1 CDJ47168.1 - 0.16 12.0 0.0 0.16 12.0 0.0 2.0 2 1 0 2 2 2 0 Exosome complex exonuclease Rrp40 N-terminal domain EcsB PF05975.12 CDJ47168.1 - 0.24 10.2 0.0 0.3 9.9 0.0 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB SARAF PF06682.12 CDJ47168.1 - 0.25 10.9 14.9 0.3 10.7 14.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis EphA2_TM PF14575.6 CDJ47168.1 - 0.29 12.1 11.1 0.38 11.7 1.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Folliculin PF11704.8 CDJ47168.1 - 0.37 10.6 7.9 0.55 10.1 7.9 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Trp_oprn_chp PF09534.10 CDJ47168.1 - 0.8 9.5 7.8 4.2 7.1 7.8 1.8 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Rsc14 PF08586.10 CDJ47168.1 - 0.93 10.3 8.0 2 9.3 0.7 2.1 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit CSG2 PF16965.5 CDJ47168.1 - 1 8.2 2.5 1.3 7.9 2.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator TAP42 PF04177.12 CDJ47168.1 - 1.2 8.2 16.5 1.4 7.9 16.5 1.1 1 0 0 1 1 1 0 TAP42-like family Serinc PF03348.15 CDJ47168.1 - 1.2 8.0 4.7 2.4 7.0 4.7 1.5 1 1 0 1 1 1 0 Serine incorporator (Serinc) FHIPEP PF00771.20 CDJ47168.1 - 1.6 7.1 15.6 5.2 5.4 15.6 1.6 1 1 0 1 1 1 0 FHIPEP family FAM176 PF14851.6 CDJ47168.1 - 1.9 8.1 8.4 1.8 8.2 0.9 2.0 2 0 0 2 2 2 0 FAM176 family Cas1_AcylT PF07779.12 CDJ47168.1 - 2.1 7.1 4.9 10 4.9 0.2 2.0 2 0 0 2 2 2 0 10 TM Acyl Transferase domain found in Cas1p Connexin PF00029.19 CDJ47168.1 - 2.6 7.7 8.1 6.5 6.4 1.3 2.0 2 0 0 2 2 2 0 Connexin DUF2973 PF11189.8 CDJ47168.1 - 3.4 7.8 11.8 0.33 11.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) RskA PF10099.9 CDJ47168.1 - 3.5 7.9 27.2 11 6.3 27.2 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ47168.1 - 3.5 7.2 54.3 3.6 7.1 21.8 2.0 2 0 0 2 2 2 0 Spt20 family Hid1 PF12722.7 CDJ47168.1 - 4.4 5.3 9.6 5.3 5.0 9.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Renin_r PF07850.14 CDJ47168.1 - 6.8 7.4 7.0 12 6.6 0.5 2.1 2 0 0 2 2 2 0 Renin receptor-like protein DUF1980 PF09323.10 CDJ47168.1 - 8.5 6.3 12.9 6.1 6.7 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) UPF0239 PF06783.11 CDJ47168.1 - 8.5 6.6 9.0 9.7 6.5 0.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) RNA_pol_Rbc25 PF08292.12 CDJ47168.1 - 9.9 6.4 15.1 1.9 8.7 2.6 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 CTP_transf_1 PF01148.20 CDJ47169.1 - 5.8e-08 32.8 0.0 8.3e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Apt1 PF10351.9 CDJ47170.1 - 1.1 8.0 33.0 1.3 7.8 33.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Band_3_cyto PF07565.13 CDJ47170.1 - 3.1 7.5 11.9 3.9 7.2 11.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SLC12 PF03522.15 CDJ47170.1 - 3.2 6.7 11.7 3.6 6.5 11.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 CDJ47170.1 - 3.7 6.0 32.9 4.5 5.7 32.9 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 CDJ47170.1 - 3.9 7.3 31.4 4.4 7.1 31.4 1.0 1 0 0 1 1 1 0 SPX domain MDFI PF15316.6 CDJ47170.1 - 6 6.9 17.6 8.8 6.4 17.6 1.3 1 0 0 1 1 1 0 MyoD family inhibitor NPR3 PF03666.13 CDJ47170.1 - 7.2 5.3 20.8 9.7 4.8 20.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ47170.1 - 8 5.1 21.0 9.8 4.8 21.0 1.0 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CDJ47170.1 - 9.6 6.1 11.2 11 5.9 11.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Shadoo PF14999.6 CDJ47171.1 - 0.0029 17.7 10.6 0.0029 17.7 10.6 1.5 1 1 0 1 1 1 1 Shadow of prion protein, neuroprotective DUF4614 PF15391.6 CDJ47171.1 - 0.2 11.6 20.8 0.27 11.2 20.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) FAM117 PF15388.6 CDJ47171.1 - 0.26 10.7 17.5 0.31 10.4 17.5 1.1 1 0 0 1 1 1 0 Protein Family FAM117 RIFIN PF02009.16 CDJ47171.1 - 0.27 11.1 7.4 0.32 10.8 7.4 1.1 1 0 0 1 1 1 0 Rifin PAP1 PF08601.10 CDJ47171.1 - 0.46 10.2 25.4 0.55 9.9 25.4 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Nop14 PF04147.12 CDJ47171.1 - 0.88 7.7 10.7 0.97 7.6 10.7 1.0 1 0 0 1 1 1 0 Nop14-like family MID_MedPIWI PF18296.1 CDJ47171.1 - 1.2 8.8 10.6 1.4 8.6 10.6 1.2 1 0 0 1 1 1 0 MID domain of medPIWI DUF3824 PF12868.7 CDJ47171.1 - 1.6 9.4 13.8 0.2 12.3 9.2 1.7 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) DUF3807 PF12720.7 CDJ47171.1 - 1.8 8.8 9.9 2.3 8.5 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SR-25 PF10500.9 CDJ47171.1 - 2.5 7.7 41.6 2.5e+02 1.1 41.6 2.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Velvet PF11754.8 CDJ47171.1 - 3.1 7.7 12.2 3.7 7.4 12.2 1.1 1 0 0 1 1 1 0 Velvet factor Apt1 PF10351.9 CDJ47171.1 - 4.6 6.0 17.8 4.9 5.9 17.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF572 PF04502.13 CDJ47171.1 - 4.6 6.8 13.7 5 6.7 13.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S64 PF08192.11 CDJ47171.1 - 4.9 5.5 14.3 5.2 5.4 14.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 PA26 PF04636.13 CDJ47171.1 - 5.2 5.9 7.0 5.4 5.8 7.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SOBP PF15279.6 CDJ47171.1 - 5.3 7.6 14.1 6.1 7.4 14.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Pannexin_like PF12534.8 CDJ47171.1 - 7.8 5.5 7.0 9.2 5.2 7.0 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Hydin_ADK PF17213.3 CDJ47171.1 - 8.2 6.7 18.1 11 6.3 18.1 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 CDJ47171.1 - 8.7 5.0 15.2 10 4.8 15.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4228 PF14009.6 CDJ47172.1 - 1.1 9.7 19.6 1.6 9.1 8.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CLN3 PF02487.17 CDJ47172.1 - 2.2 7.2 24.2 0.23 10.4 7.1 2.1 2 0 0 2 2 2 0 CLN3 protein BORG_CEP PF14957.6 CDJ47172.1 - 5.9 8.1 24.7 12 7.1 9.6 2.2 2 0 0 2 2 2 0 Cdc42 effector Coilin_N PF15862.5 CDJ47172.1 - 9.9 6.0 39.7 0.13 12.1 9.5 3.1 3 0 0 3 3 3 0 Coilin N-terminus RskA PF10099.9 CDJ47173.1 - 2 8.7 14.1 4.2 7.6 14.1 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF3657 PF12394.8 CDJ47174.1 - 0.00011 22.7 0.0 0.00011 22.7 0.0 5.1 5 1 0 5 5 5 1 Protein FAM135 Spt20 PF12090.8 CDJ47176.1 - 0.038 13.6 58.8 0.099 12.2 16.2 2.5 2 0 0 2 2 2 0 Spt20 family SART-1 PF03343.13 CDJ47176.1 - 0.061 11.9 13.6 0.096 11.2 13.6 1.2 1 0 0 1 1 1 0 SART-1 family TYW3 PF02676.14 CDJ47176.1 - 0.11 11.9 5.4 0.25 10.7 5.4 1.6 1 0 0 1 1 1 0 Methyltransferase TYW3 DUF1708 PF08101.11 CDJ47176.1 - 0.12 11.4 10.4 0.19 10.8 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Tub PF01167.18 CDJ47176.1 - 0.14 11.9 9.7 0.24 11.1 9.7 1.3 1 0 0 1 1 1 0 Tub family Kelch_1 PF01344.25 CDJ47176.1 - 0.29 10.7 5.0 11 5.6 1.3 3.2 2 1 0 2 2 2 0 Kelch motif SLC12 PF03522.15 CDJ47176.1 - 0.93 8.4 17.8 1.5 7.8 17.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S49_N PF08496.10 CDJ47176.1 - 5 7.2 11.3 8.5 6.4 6.7 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal U1snRNP70_N PF12220.8 CDJ47176.1 - 6.4 7.5 15.3 7.1 7.4 6.9 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal XRN_M PF17846.1 CDJ47176.1 - 6.4 5.6 10.8 12 4.7 10.8 1.4 1 0 0 1 1 1 0 Xrn1 helical domain Thg1C PF14413.6 CDJ47176.1 - 8.7 6.5 15.0 5.3 7.2 8.5 2.4 2 0 0 2 2 2 0 Thg1 C terminal domain Spt20 PF12090.8 CDJ47177.1 - 0.00027 20.6 14.2 0.00048 19.8 14.2 1.4 1 0 0 1 1 1 1 Spt20 family EphA2_TM PF14575.6 CDJ47177.1 - 0.22 12.4 2.7 0.79 10.6 1.4 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4647 PF15504.6 CDJ47177.1 - 0.35 9.9 7.7 0.44 9.6 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) WBP-1 PF11669.8 CDJ47177.1 - 0.54 10.9 3.8 1.3 9.7 3.8 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 MAP65_ASE1 PF03999.12 CDJ47177.1 - 1 8.0 10.5 1.2 7.7 10.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SLC12 PF03522.15 CDJ47177.1 - 7.5 5.5 8.9 9.8 5.1 8.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RskA PF10099.9 CDJ47178.1 - 0.0014 19.0 10.1 0.0019 18.6 10.1 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Glyco_hydro_9 PF00759.19 CDJ47178.1 - 0.01 15.3 6.3 0.011 15.2 6.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 SR-25 PF10500.9 CDJ47178.1 - 0.015 14.9 16.8 0.017 14.8 16.8 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Shadoo PF14999.6 CDJ47178.1 - 0.018 15.2 4.3 0.029 14.5 4.3 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Hist_deacetyl PF00850.19 CDJ47178.1 - 0.11 11.9 2.8 0.11 11.9 2.8 1.0 1 0 0 1 1 1 0 Histone deacetylase domain Ribosomal_60s PF00428.19 CDJ47178.1 - 0.18 12.4 7.7 0.26 11.9 7.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3138 PF11336.8 CDJ47178.1 - 0.22 10.1 15.4 0.24 9.9 15.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4569 PF15133.6 CDJ47178.1 - 0.8 9.4 11.9 0.95 9.1 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) CDK2AP PF09806.9 CDJ47178.1 - 1.6 8.8 16.2 1.8 8.6 16.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Rpp20 PF12328.8 CDJ47178.1 - 1.9 8.4 9.4 2.8 7.9 9.4 1.3 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P SUIM_assoc PF16619.5 CDJ47178.1 - 3.3 7.8 32.7 0.083 13.0 14.3 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Activator_LAG-3 PF11498.8 CDJ47178.1 - 10 5.0 36.6 11 4.9 36.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Exonuc_VII_L PF02601.15 CDJ47180.1 - 0.0026 17.4 3.5 0.0026 17.4 3.5 8.2 6 3 0 7 7 7 3 Exonuclease VII, large subunit DUF2722 PF10846.8 CDJ47181.1 - 1.7e-05 23.9 3.2 2.1e-05 23.6 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ47181.1 - 0.011 15.7 2.7 0.015 15.3 2.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) WD40 PF00400.32 CDJ47181.1 - 0.021 15.7 0.1 0.051 14.5 0.1 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat CNDH2_M PF16869.5 CDJ47181.1 - 0.037 14.7 0.1 0.049 14.3 0.1 1.3 1 0 0 1 1 1 0 PF16858 Spt20 PF12090.8 CDJ47181.1 - 0.066 12.8 19.2 0.087 12.4 19.2 1.1 1 0 0 1 1 1 0 Spt20 family TERB2 PF15101.6 CDJ47181.1 - 0.3 11.1 4.5 0.44 10.6 4.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 UPF0560 PF10577.9 CDJ47181.1 - 0.5 8.8 7.9 0.68 8.4 7.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 BRF1 PF07741.13 CDJ47181.1 - 0.91 9.9 7.1 1.9 8.8 7.1 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Conotoxin PF02950.17 CDJ47181.1 - 1.2 10.2 4.4 3 8.9 3.5 2.1 2 0 0 2 2 2 0 Conotoxin Presenilin PF01080.17 CDJ47181.1 - 3.3 6.4 5.2 4.9 5.8 5.2 1.2 1 0 0 1 1 1 0 Presenilin NLE PF08154.12 CDJ47182.1 - 4.8e-17 62.2 0.2 6.6e-17 61.8 0.2 1.1 1 0 0 1 1 1 1 NLE (NUC135) domain Foie-gras_1 PF11817.8 CDJ47182.1 - 0.22 11.1 0.3 0.25 10.9 0.3 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 SR-25 PF10500.9 CDJ47182.1 - 4.5 6.8 20.7 6.3 6.3 20.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LsmAD PF06741.13 CDJ47183.1 - 3.4e-08 33.9 0.0 3.4e-08 33.9 0.0 3.3 3 0 0 3 3 3 1 LsmAD domain CLN3 PF02487.17 CDJ47185.1 - 0.00031 19.9 6.7 0.00046 19.4 6.7 1.2 1 0 0 1 1 1 1 CLN3 protein HemX PF04375.14 CDJ47185.1 - 0.0014 18.0 31.4 0.0014 18.0 31.4 2.0 2 0 0 2 2 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase CCSAP PF15748.5 CDJ47185.1 - 0.0027 18.0 15.2 0.0037 17.5 15.2 1.4 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated SID-1_RNA_chan PF13965.6 CDJ47185.1 - 0.0052 15.3 0.2 0.0052 15.3 0.2 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 SAPS PF04499.15 CDJ47185.1 - 0.0064 15.3 6.6 0.0071 15.2 6.6 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SLC12 PF03522.15 CDJ47185.1 - 0.011 14.8 11.7 0.013 14.6 11.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF4131 PF13567.6 CDJ47185.1 - 0.011 15.4 1.7 0.035 13.7 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DDHD PF02862.17 CDJ47185.1 - 0.017 15.3 10.5 0.023 14.9 10.5 1.3 1 0 0 1 1 1 0 DDHD domain PIP5K PF01504.18 CDJ47185.1 - 0.02 14.1 6.1 0.022 14.0 6.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SDF PF00375.18 CDJ47185.1 - 0.034 13.2 0.3 0.061 12.3 0.3 1.5 1 1 0 1 1 1 0 Sodium:dicarboxylate symporter family SpoIIP PF07454.11 CDJ47185.1 - 0.036 13.5 14.5 0.052 13.0 14.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Serinc PF03348.15 CDJ47185.1 - 0.048 12.6 4.3 0.064 12.2 4.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Phage_holin_2_4 PF16082.5 CDJ47185.1 - 0.055 13.2 0.4 0.055 13.2 0.4 2.7 1 1 1 2 2 1 0 Bacteriophage holin family, superfamily II-like Mem_trans PF03547.18 CDJ47185.1 - 0.071 11.5 0.5 0.082 11.3 0.5 1.2 1 0 0 1 1 1 0 Membrane transport protein FAM176 PF14851.6 CDJ47185.1 - 0.073 12.7 6.8 0.13 11.9 6.8 1.4 1 0 0 1 1 1 0 FAM176 family FAM60A PF15396.6 CDJ47185.1 - 0.12 12.4 9.4 0.17 11.9 9.4 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SARAF PF06682.12 CDJ47185.1 - 0.12 12.0 13.0 0.16 11.6 13.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF913 PF06025.12 CDJ47185.1 - 0.14 11.1 7.5 0.18 10.8 7.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Gti1_Pac2 PF09729.9 CDJ47185.1 - 0.23 11.5 14.1 0.14 12.2 11.7 1.8 2 0 0 2 2 2 0 Gti1/Pac2 family DcuA_DcuB PF03605.14 CDJ47185.1 - 0.23 10.3 1.6 0.42 9.5 1.6 1.5 1 1 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter CSG2 PF16965.5 CDJ47185.1 - 0.29 10.0 6.1 0.4 9.6 6.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator V_ATPase_I PF01496.19 CDJ47185.1 - 0.35 8.7 18.9 0.49 8.2 18.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF-3_zeta PF05091.12 CDJ47185.1 - 0.36 9.8 18.0 0.45 9.4 18.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pannexin_like PF12534.8 CDJ47185.1 - 0.38 9.8 8.2 0.56 9.2 8.2 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Hid1 PF12722.7 CDJ47185.1 - 0.45 8.6 13.4 0.54 8.3 13.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Radical_SAM_N PF08497.10 CDJ47185.1 - 0.47 9.7 6.0 0.56 9.4 6.0 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal GREB1 PF15782.5 CDJ47185.1 - 0.49 7.4 13.5 0.55 7.3 13.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Connexin PF00029.19 CDJ47185.1 - 0.61 9.8 12.9 1 9.1 12.9 1.4 1 0 0 1 1 1 0 Connexin ArAE_2_N PF10337.9 CDJ47185.1 - 1.2 8.1 8.1 1.7 7.6 8.1 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF2072 PF09845.9 CDJ47185.1 - 1.3 9.2 11.4 2.4 8.4 11.4 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein Neur_chan_memb PF02932.16 CDJ47185.1 - 1.4 8.9 16.3 0.011 15.8 8.3 1.6 2 0 0 2 2 1 0 Neurotransmitter-gated ion-channel transmembrane region Trp_oprn_chp PF09534.10 CDJ47185.1 - 1.5 8.6 7.8 0.097 12.5 1.6 1.8 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) O-antigen_lig PF13425.6 CDJ47185.1 - 1.6 7.5 8.2 2.4 6.9 8.2 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Folate_carrier PF01770.18 CDJ47185.1 - 1.7 7.3 6.4 2.6 6.7 6.4 1.4 1 0 0 1 1 1 0 Reduced folate carrier LMBR1 PF04791.16 CDJ47185.1 - 3.7 6.3 6.5 4.8 6.0 6.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CBP_BcsG PF11658.8 CDJ47185.1 - 4 5.7 11.9 5.6 5.2 11.9 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Presenilin PF01080.17 CDJ47185.1 - 4.8 5.8 25.5 8 5.1 25.5 1.3 1 0 0 1 1 1 0 Presenilin CAF1 PF04857.20 CDJ47185.1 - 6.1 5.9 14.7 9.6 5.3 14.7 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease Ureide_permease PF07168.11 CDJ47185.1 - 7.8 5.1 6.4 12 4.5 6.4 1.4 1 0 0 1 1 1 0 Ureide permease Cellulose_synt PF03552.14 CDJ47185.1 - 8.3 4.8 5.7 10 4.4 5.7 1.1 1 0 0 1 1 1 0 Cellulose synthase HTH_11 PF08279.12 CDJ47186.1 - 0.061 13.3 0.0 0.23 11.4 0.0 2.0 1 0 0 1 1 1 0 HTH domain HTH_23 PF13384.6 CDJ47186.1 - 0.18 11.7 3.2 0.18 11.6 0.1 2.8 2 0 0 2 2 2 0 Homeodomain-like domain MarR PF01047.22 CDJ47186.1 - 0.4 10.7 2.3 0.53 10.3 0.1 2.4 2 0 0 2 2 2 0 MarR family MMR1 PF08505.10 CDJ47187.1 - 0.041 14.2 16.3 0.05 13.9 16.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FHIPEP PF00771.20 CDJ47187.1 - 0.29 9.5 12.6 0.43 9.0 12.6 1.2 1 0 0 1 1 1 0 FHIPEP family MRP-63 PF14978.6 CDJ47187.1 - 0.59 10.8 14.2 0.34 11.5 0.5 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 Exonuc_VII_L PF02601.15 CDJ47187.1 - 0.66 9.5 26.0 0.78 9.2 26.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Presenilin PF01080.17 CDJ47187.1 - 0.87 8.3 18.4 0.96 8.1 18.4 1.2 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 CDJ47187.1 - 0.96 9.0 16.7 1.1 8.8 16.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ALMT PF11744.8 CDJ47187.1 - 1.6 7.5 11.0 1.7 7.4 11.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Miff PF05644.11 CDJ47187.1 - 1.8 8.1 16.3 2.1 7.9 16.3 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff OATP PF03137.20 CDJ47187.1 - 2.2 6.5 7.4 2.8 6.1 7.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Membralin PF09746.9 CDJ47187.1 - 3.2 6.7 9.5 3.8 6.5 9.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein SLC12 PF03522.15 CDJ47187.1 - 3.4 6.6 17.8 3.9 6.4 17.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CLN3 PF02487.17 CDJ47187.1 - 3.9 6.4 13.3 5.8 5.9 13.3 1.2 1 0 0 1 1 1 0 CLN3 protein PAT1 PF09770.9 CDJ47187.1 - 4.2 5.5 33.4 4.4 5.5 33.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4647 PF15504.6 CDJ47187.1 - 5.8 5.9 20.4 6.9 5.7 20.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) SRP-alpha_N PF04086.13 CDJ47187.1 - 6.7 6.5 21.5 8.5 6.2 21.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MDM10 PF12519.8 CDJ47187.1 - 7.2 5.4 14.6 8.2 5.2 14.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Glyco_hydro81C PF17652.1 CDJ47188.1 - 0.06 12.6 0.4 2.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 81 C-terminal domain DUF966 PF06136.13 CDJ47189.1 - 0.05 13.3 20.9 0.062 13.0 20.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) XRN_M PF17846.1 CDJ47189.1 - 0.4 9.6 2.1 0.48 9.3 2.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain AAA_29 PF13555.6 CDJ47190.1 - 0.00051 19.7 0.0 0.0017 18.1 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CDJ47190.1 - 0.00083 19.8 0.0 0.00083 19.8 0.0 2.7 2 1 0 2 2 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 CDJ47190.1 - 0.01 15.6 0.3 0.018 14.8 0.3 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 CDJ47190.1 - 0.015 14.5 0.1 0.015 14.5 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 CDJ47190.1 - 0.043 14.4 0.2 0.043 14.4 0.2 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDJ47190.1 - 0.063 13.6 0.7 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CDJ47190.1 - 0.087 13.0 0.2 0.087 13.0 0.2 2.9 3 1 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 CDJ47190.1 - 0.097 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 CDJ47190.1 - 0.099 12.6 0.3 0.099 12.6 0.3 1.9 2 0 0 2 2 2 0 NACHT domain Viral_helicase1 PF01443.18 CDJ47190.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 CDJ47190.1 - 0.13 10.2 0.1 0.13 10.2 0.1 1.6 2 0 0 2 2 2 0 Helicase cobW PF02492.19 CDJ47190.1 - 0.15 11.7 0.2 0.15 11.7 0.2 1.7 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 CDJ47190.1 - 0.24 11.9 0.4 0.24 11.9 0.4 2.4 1 1 1 2 2 1 0 ABC transporter AAA_23 PF13476.6 CDJ47190.1 - 0.62 10.5 0.0 0.62 10.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain SPX PF03105.19 CDJ47190.1 - 2.4 8.0 26.3 3.2 7.6 26.3 1.2 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 CDJ47190.1 - 3.4 7.2 37.1 0.055 13.1 18.4 2.2 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 CDJ47190.1 - 4.6 6.9 22.2 2.7 7.7 8.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Dynamin_N PF00350.23 CDJ47190.1 - 6.2 6.9 8.9 9.5 6.2 0.2 3.1 3 0 0 3 3 3 0 Dynamin family RRM_1 PF00076.22 CDJ47192.1 - 0.0077 16.0 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IMUP PF15761.5 CDJ47192.1 - 0.0098 16.6 4.6 0.0098 16.6 4.6 3.3 2 1 1 3 3 3 1 Immortalisation up-regulated protein Lin-8 PF03353.15 CDJ47192.1 - 0.25 10.9 37.8 0.45 10.0 2.1 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Shadoo PF14999.6 CDJ47192.1 - 0.36 10.9 6.4 3.6 7.7 1.5 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective PAP1 PF08601.10 CDJ47192.1 - 4.1 7.0 26.4 0.97 9.1 16.7 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 PRIMA1 PF16101.5 CDJ47192.1 - 8.8 6.4 15.7 0.17 12.0 1.4 2.8 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 DUF4148 PF13663.6 CDJ47192.1 - 9.6 6.5 19.6 1.4 9.1 0.2 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Pex14_N PF04695.13 CDJ47193.1 - 0.0096 16.6 12.0 0.0096 16.6 12.0 12.5 7 2 2 9 9 9 4 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.13 CDJ47194.1 - 0.0048 16.0 25.8 0.006 15.7 25.8 1.0 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.9 CDJ47194.1 - 0.16 11.5 26.3 0.25 10.9 26.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 CDJ47194.1 - 3.2 4.8 27.5 3.9 4.5 27.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 CDJ47194.1 - 4.5 6.3 30.2 5.3 6.0 30.2 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF966 PF06136.13 CDJ47194.1 - 5.6 6.6 23.3 8.6 6.0 23.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SLC12 PF03522.15 CDJ47194.1 - 7.5 5.5 26.0 12 4.8 26.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 SOBP PF15279.6 CDJ47194.1 - 8.3 6.9 31.6 10 6.6 31.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SWI-SNF_Ssr4 PF08549.10 CDJ47194.1 - 8.7 4.8 33.5 9.6 4.7 33.5 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) NESP55 PF06390.12 CDJ47195.1 - 0.042 13.4 50.8 0.28 10.8 19.4 2.1 1 1 1 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 CDJ47195.1 - 2.2 8.3 46.4 2.2 8.3 21.7 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) SET PF00856.28 CDJ47196.1 - 1.4e-14 54.8 0.2 1.4e-14 54.8 0.2 4.8 2 2 0 2 2 2 1 SET domain DUF2722 PF10846.8 CDJ47196.1 - 0.0063 15.5 3.2 0.0063 15.5 3.2 5.0 3 2 0 3 3 3 1 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ47196.1 - 1.1 10.2 0.1 0.094 13.7 1.1 5.6 4 2 0 4 4 4 0 Domain of unknown function (DUF4834) DUF4079 PF13301.6 CDJ47196.1 - 7.7 6.7 11.7 0.78 9.9 0.1 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) MobB PF03205.14 CDJ47197.1 - 0.012 15.6 0.7 0.012 15.6 0.7 2.0 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4820 PF16091.5 CDJ47197.1 - 2.2 7.6 25.0 3 7.2 25.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM60A PF15396.6 CDJ47197.1 - 3.4 7.6 27.3 4.9 7.1 27.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Pex14_N PF04695.13 CDJ47199.1 - 0.0036 18.0 8.8 0.0048 17.6 8.8 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Lin-8 PF03353.15 CDJ47199.1 - 0.0054 16.3 9.2 0.0064 16.1 9.2 1.0 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Nop53 PF07767.11 CDJ47199.1 - 0.021 14.2 14.0 0.025 14.0 14.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) THEG4 PF15834.5 CDJ47199.1 - 0.076 13.0 1.8 0.088 12.8 1.8 1.0 1 0 0 1 1 1 0 Testis highly expressed protein 4 TFIIA PF03153.13 CDJ47199.1 - 0.092 12.7 23.6 0.11 12.5 23.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 CDJ47199.1 - 0.097 11.9 2.8 0.13 11.5 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 CDJ47199.1 - 0.1 10.9 5.9 0.11 10.8 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein CCSAP PF15748.5 CDJ47199.1 - 0.17 12.1 9.3 0.19 11.9 9.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ47199.1 - 0.32 10.8 10.1 0.39 10.5 10.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4175 PF13779.6 CDJ47199.1 - 0.54 8.1 24.6 0.62 7.9 24.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.14 CDJ47199.1 - 1.4 8.9 10.1 1.6 8.6 10.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ47199.1 - 2.2 7.0 9.4 2.6 6.7 9.4 1.1 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 CDJ47200.1 - 0.38 8.8 32.5 0.53 8.3 32.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NPR3 PF03666.13 CDJ47200.1 - 0.59 8.9 34.2 0.73 8.6 34.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ47200.1 - 1.1 7.9 47.1 1.3 7.8 47.1 1.0 1 0 0 1 1 1 0 Presenilin Endostatin PF06482.11 CDJ47200.1 - 2.2 7.7 40.3 3 7.2 40.3 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin RR_TM4-6 PF06459.12 CDJ47200.1 - 2.4 7.9 40.4 3 7.6 40.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2052 PF09747.9 CDJ47200.1 - 3.6 7.7 39.2 4.7 7.3 39.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Vac7 PF12751.7 CDJ47200.1 - 6.8 6.0 20.5 8.1 5.8 20.5 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DnaJ PF00226.31 CDJ47201.1 - 9.8e-12 44.8 0.1 4.6e-11 42.7 0.1 2.2 1 0 0 1 1 1 1 DnaJ domain Hist_deacetyl PF00850.19 CDJ47201.1 - 9.2 5.6 19.9 1.4 8.3 7.2 2.5 2 0 0 2 2 2 0 Histone deacetylase domain KH_1 PF00013.29 CDJ47202.1 - 1.3e-41 140.2 0.0 1.4e-11 44.1 0.2 6.3 6 0 0 6 6 6 5 KH domain KH_2 PF07650.17 CDJ47202.1 - 0.1 12.4 0.0 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 KH domain Pkinase PF00069.25 CDJ47203.1 - 6.9e-24 84.6 0.0 3.8e-23 82.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ47203.1 - 3e-23 82.6 0.0 4e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ47203.1 - 1.7e-07 30.8 0.0 2.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ47203.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gln-synt_N_2 PF16952.5 CDJ47203.1 - 0.16 11.8 0.1 3.3 7.6 0.0 2.7 3 0 0 3 3 3 0 Glutamine synthetase N-terminal domain ABC1 PF03109.16 CDJ47204.1 - 3e-24 85.5 0.0 5.9e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Beta-lactamase PF00144.24 CDJ47204.1 - 1.1e-22 80.8 0.2 6.9e-09 35.4 0.0 4.2 3 1 1 4 4 4 3 Beta-lactamase MFS_1 PF07690.16 CDJ47204.1 - 1.2e-11 44.1 35.1 1.7e-07 30.5 15.5 2.7 1 1 1 3 3 3 3 Major Facilitator Superfamily WaaY PF06176.11 CDJ47204.1 - 0.0087 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RelB_transactiv PF16181.5 CDJ47204.1 - 0.12 12.7 4.9 0.023 15.0 1.0 1.8 2 0 0 2 2 2 0 RelB transactivation domain RabGAP-TBC PF00566.18 CDJ47205.1 - 3.3e-29 102.1 0.3 3.3e-29 102.1 0.3 3.1 4 0 0 4 4 4 2 Rab-GTPase-TBC domain BRF1 PF07741.13 CDJ47205.1 - 3.8 7.9 5.0 7 7.1 1.1 2.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Kinase-like PF14531.6 CDJ47206.1 - 2.6e-16 59.8 0.0 4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 CDJ47206.1 - 0.0094 15.3 0.0 0.026 13.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain SOBP PF15279.6 CDJ47206.1 - 0.3 11.7 11.9 0.47 11.0 11.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Herpes_BLLF1 PF05109.13 CDJ47206.1 - 1 7.3 33.4 1.5 6.7 33.4 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Mito_carr PF00153.27 CDJ47207.1 - 9.9e-12 44.6 13.2 8.2e-09 35.3 1.4 3.6 2 2 2 4 4 4 2 Mitochondrial carrier protein Adap_comp_sub PF00928.21 CDJ47208.1 - 1.1e-86 290.5 0.0 1.4e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ47208.1 - 2.8e-05 24.1 0.1 5.4e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SNF2_N PF00176.23 CDJ47209.1 - 1.8e-42 145.4 0.0 7.2e-36 123.6 0.0 4.6 4 1 1 5 5 5 2 SNF2 family N-terminal domain RT_RNaseH_2 PF17919.1 CDJ47210.1 - 1.1e-28 99.2 0.0 2.9e-28 97.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ47210.1 - 1.3e-28 99.4 0.1 2.8e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ47210.1 - 5.1e-17 62.1 0.0 8e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CDJ47210.1 - 4.9e-08 32.8 0.0 9.2e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ47210.1 - 7.4e-08 32.9 0.0 1.6e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ47210.1 - 9.6e-07 29.3 0.0 2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ47210.1 - 0.0037 17.1 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_3 PF13456.6 CDJ47210.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like RVP PF00077.20 CDJ47210.1 - 0.071 13.4 0.0 0.24 11.7 0.0 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease Chromo PF00385.24 CDJ47211.1 - 1.6e-10 40.8 0.0 3.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CGI-121 PF08617.10 CDJ47212.1 - 1.1e-11 45.1 9.3 7.7e-10 39.1 0.1 3.6 3 1 0 3 3 3 1 Kinase binding protein CGI-121 TFIIA PF03153.13 CDJ47212.1 - 2e-07 31.4 30.3 0.00019 21.5 7.7 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.11 CDJ47212.1 - 0.00025 21.3 18.5 0.00025 21.3 18.5 5.4 4 1 1 5 5 3 1 Domain of unknown function (DUF755) DUF1645 PF07816.11 CDJ47212.1 - 0.005 17.4 5.1 0.005 17.4 5.1 4.4 3 2 0 3 3 1 1 Protein of unknown function (DUF1645) Apt1 PF10351.9 CDJ47212.1 - 0.0066 15.4 2.9 0.0066 15.4 2.9 2.9 3 0 0 3 3 2 1 Golgi-body localisation protein domain Spt20 PF12090.8 CDJ47212.1 - 0.0089 15.7 19.5 0.0089 15.7 19.5 2.3 2 0 0 2 2 2 1 Spt20 family EPL1 PF10513.9 CDJ47212.1 - 0.014 15.7 0.5 0.014 15.7 0.5 2.6 2 1 0 2 2 1 0 Enhancer of polycomb-like BORG_CEP PF14957.6 CDJ47212.1 - 0.018 16.2 3.4 0.018 16.2 3.4 3.3 3 0 0 3 3 3 0 Cdc42 effector Mem_trans PF03547.18 CDJ47212.1 - 0.019 13.4 0.2 0.019 13.4 0.2 2.1 2 0 0 2 2 2 0 Membrane transport protein PepSY_TM PF03929.16 CDJ47212.1 - 0.059 13.0 7.4 0.17 11.5 0.3 2.2 2 0 0 2 2 2 0 PepSY-associated TM region Tim54 PF11711.8 CDJ47212.1 - 0.072 11.9 4.2 0.21 10.3 0.1 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pet20 PF08692.10 CDJ47212.1 - 0.15 12.7 3.8 3.1 8.5 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial protein Pet20 MPM1 PF17234.2 CDJ47212.1 - 0.31 11.3 18.1 0.95 9.7 9.0 2.5 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 RCR PF12273.8 CDJ47212.1 - 0.43 11.2 8.7 0.36 11.5 0.2 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red RAB3GAP2_N PF14655.6 CDJ47212.1 - 0.55 9.4 15.8 0.21 10.8 4.2 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Thg1C PF14413.6 CDJ47212.1 - 0.67 10.1 9.0 5.4 7.2 1.1 2.4 2 0 0 2 2 2 0 Thg1 C terminal domain DUF572 PF04502.13 CDJ47212.1 - 0.71 9.4 18.3 3.2 7.3 10.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Med15 PF09606.10 CDJ47212.1 - 0.79 8.3 38.1 0.27 9.9 11.9 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal stn_TNFRSF12A PF12191.8 CDJ47212.1 - 1.3 9.2 0.0 1.3 9.2 0.0 3.4 3 1 2 5 5 4 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain CLN3 PF02487.17 CDJ47212.1 - 1.8 7.5 8.6 0.36 9.8 1.1 2.4 2 0 0 2 2 2 0 CLN3 protein MMM1 PF10296.9 CDJ47212.1 - 2.4 7.1 9.3 0.8 8.7 2.5 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 DUF913 PF06025.12 CDJ47212.1 - 2.6 6.9 12.4 1 8.3 5.8 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Mak16 PF04874.14 CDJ47212.1 - 2.8 8.6 10.5 4.6 7.9 1.2 2.3 2 0 0 2 2 2 0 Mak16 protein C-terminal region CPSF100_C PF13299.6 CDJ47212.1 - 3.2 7.9 16.3 5.9 7.1 1.5 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Membr_traf_MHD PF10540.9 CDJ47212.1 - 3.3 7.9 8.6 0.83 9.8 2.4 2.4 2 0 0 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain Acid_PPase PF12689.7 CDJ47212.1 - 4.4 7.1 6.0 0.63 9.9 0.8 1.9 2 0 0 2 2 2 0 Acid Phosphatase PRC2_HTH_1 PF18118.1 CDJ47212.1 - 4.6 8.1 10.2 7.6 7.4 4.4 2.7 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain FixO PF02433.15 CDJ47212.1 - 4.8 6.6 8.4 1.4 8.3 0.5 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO FAM176 PF14851.6 CDJ47212.1 - 5.3 6.7 8.1 16 5.1 5.1 2.5 2 0 0 2 2 2 0 FAM176 family DUF4770 PF15994.5 CDJ47212.1 - 8 6.7 16.7 2.1 8.6 5.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF3408 PF11888.8 CDJ47212.1 - 8.8 6.5 14.7 6.7 6.9 5.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF2722 PF10846.8 CDJ47213.1 - 6.6e-05 22.0 12.9 0.0001 21.4 12.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) MAP65_ASE1 PF03999.12 CDJ47213.1 - 0.015 14.0 5.2 0.022 13.5 5.2 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SpoIIP PF07454.11 CDJ47213.1 - 0.12 11.8 3.5 0.18 11.3 3.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) MMR1 PF08505.10 CDJ47213.1 - 0.19 12.0 7.8 0.28 11.4 7.8 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Lin-8 PF03353.15 CDJ47213.1 - 0.26 10.8 10.5 0.45 10.0 10.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PIP5K PF01504.18 CDJ47213.1 - 0.31 10.2 2.3 0.44 9.7 2.3 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase eIF-3_zeta PF05091.12 CDJ47213.1 - 0.7 8.8 11.3 0.9 8.4 11.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Plasmodium_Vir PF05795.11 CDJ47213.1 - 1 8.7 2.9 1.5 8.1 2.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TERB2 PF15101.6 CDJ47213.1 - 2.2 8.3 11.5 3.7 7.5 11.5 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EIIBC-GUT_N PF03612.14 CDJ47213.1 - 2.4 7.9 6.3 5.8 6.6 6.3 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Spt20 PF12090.8 CDJ47213.1 - 3.3 7.3 34.8 5.9 6.4 34.8 1.4 1 0 0 1 1 1 0 Spt20 family MCU PF04678.13 CDJ47213.1 - 3.4 7.7 5.2 6.2 6.9 5.2 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4834 PF16118.5 CDJ47213.1 - 8.3 7.4 12.5 15 6.6 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3408 PF11888.8 CDJ47213.1 - 8.8 6.5 9.5 27 4.9 9.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Tctex-1 PF03645.13 CDJ47215.1 - 1.8e-19 69.9 0.2 1.8e-19 69.9 0.2 2.2 2 0 0 2 2 1 1 Tctex-1 family Pex14_N PF04695.13 CDJ47215.1 - 0.00026 21.7 20.9 0.00056 20.6 20.9 1.6 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 CDJ47215.1 - 0.0016 16.8 27.3 0.0019 16.6 27.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ47215.1 - 0.0036 16.6 7.8 0.0042 16.3 7.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3292 PF11696.8 CDJ47215.1 - 0.0058 15.1 11.1 0.0073 14.7 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) CDC45 PF02724.14 CDJ47215.1 - 0.0079 14.5 8.6 0.0088 14.4 8.6 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF3295 PF11702.8 CDJ47215.1 - 0.016 14.6 12.8 0.02 14.3 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) PTPRCAP PF15713.5 CDJ47215.1 - 0.017 15.4 14.5 0.033 14.5 14.5 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 CDJ47215.1 - 0.028 13.2 20.0 0.036 12.8 20.0 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 CDJ47215.1 - 0.029 12.9 12.4 0.044 12.3 12.4 1.3 1 0 0 1 1 1 0 Macoilin family Anoctamin PF04547.12 CDJ47215.1 - 0.046 12.6 0.2 0.062 12.1 0.2 1.4 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF3323 PF11796.8 CDJ47215.1 - 0.061 13.2 0.2 0.061 13.2 0.2 2.4 2 1 0 2 2 1 0 Protein of unknown function N-terminus (DUF3323) GREB1 PF15782.5 CDJ47215.1 - 0.086 10.0 15.9 0.1 9.7 15.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4045 PF13254.6 CDJ47215.1 - 0.091 12.4 13.2 0.11 12.1 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) MCM_bind PF09739.9 CDJ47215.1 - 0.091 11.2 16.1 0.13 10.7 16.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Cellulose_synt PF03552.14 CDJ47215.1 - 0.12 10.8 2.4 0.15 10.5 2.4 1.1 1 0 0 1 1 1 0 Cellulose synthase CSG2 PF16965.5 CDJ47215.1 - 0.15 11.0 6.4 0.21 10.5 6.4 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator PNISR PF15996.5 CDJ47215.1 - 0.16 12.2 18.4 0.31 11.3 18.4 1.5 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR PBP1_TM PF14812.6 CDJ47215.1 - 0.17 12.3 5.2 0.33 11.4 5.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CKAP2_C PF15297.6 CDJ47215.1 - 0.19 10.8 13.4 0.28 10.2 13.4 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus NPR3 PF03666.13 CDJ47215.1 - 0.21 10.4 16.2 0.32 9.7 16.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ndc1_Nup PF09531.10 CDJ47215.1 - 0.23 10.1 8.8 0.27 9.9 8.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Vac7 PF12751.7 CDJ47215.1 - 0.27 10.7 12.6 0.42 10.0 12.6 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF913 PF06025.12 CDJ47215.1 - 0.27 10.2 8.2 0.38 9.7 8.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIP PF07454.11 CDJ47215.1 - 0.32 10.4 15.6 0.49 9.8 15.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4050 PF13259.6 CDJ47215.1 - 0.33 11.3 15.7 0.51 10.6 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Peptidase_S64 PF08192.11 CDJ47215.1 - 0.35 9.3 12.5 0.44 9.0 12.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 OATP PF03137.20 CDJ47215.1 - 0.39 9.0 7.2 0.73 8.1 7.2 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Connexin PF00029.19 CDJ47215.1 - 0.49 10.1 15.3 0.92 9.2 15.3 1.5 1 0 0 1 1 1 0 Connexin Gti1_Pac2 PF09729.9 CDJ47215.1 - 0.52 10.4 16.7 0.84 9.7 16.7 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family TYW3 PF02676.14 CDJ47215.1 - 0.63 9.4 14.7 0.85 8.9 12.8 1.8 2 0 0 2 2 2 0 Methyltransferase TYW3 Lin-8 PF03353.15 CDJ47215.1 - 0.7 9.4 20.5 0.98 8.9 20.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nucleoside_tran PF01733.18 CDJ47215.1 - 0.73 9.2 5.1 1 8.7 5.1 1.2 1 0 0 1 1 1 0 Nucleoside transporter SLC12 PF03522.15 CDJ47215.1 - 0.77 8.7 19.2 1.2 8.1 19.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PIP5K PF01504.18 CDJ47215.1 - 1 8.5 12.0 1.5 8.0 12.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase RR_TM4-6 PF06459.12 CDJ47215.1 - 1 9.1 21.6 1.6 8.5 21.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ47215.1 - 1.3 9.1 17.7 2.2 8.3 17.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 CDJ47215.1 - 1.4 7.6 18.0 0.7 8.6 16.0 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 UPF0560 PF10577.9 CDJ47215.1 - 1.5 7.2 25.3 2.1 6.7 25.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 NST1 PF13945.6 CDJ47215.1 - 1.6 8.8 26.8 3.3 7.8 26.8 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Peptidase_S49_N PF08496.10 CDJ47215.1 - 1.7 8.7 17.1 3.1 7.8 17.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SelP_N PF04592.14 CDJ47215.1 - 1.8 7.9 39.5 3 7.2 39.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3043 PF11241.8 CDJ47215.1 - 1.9 8.5 9.8 3.3 7.7 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF2126 PF09899.9 CDJ47215.1 - 1.9 6.5 13.4 2.5 6.1 13.4 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DDRGK PF09756.9 CDJ47215.1 - 1.9 8.0 25.3 3.2 7.3 25.3 1.3 1 0 0 1 1 1 0 DDRGK domain ALMT PF11744.8 CDJ47215.1 - 2.2 7.0 15.9 3.2 6.5 15.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Membralin PF09746.9 CDJ47215.1 - 2.6 7.0 11.6 3.5 6.6 11.6 1.2 1 0 0 1 1 1 0 Tumour-associated protein CCDC53 PF10152.9 CDJ47215.1 - 2.6 8.4 20.4 1.5 9.2 18.4 1.7 2 0 0 2 2 1 0 Subunit CCDC53 of WASH complex MDM10 PF12519.8 CDJ47215.1 - 2.9 6.7 15.4 3.8 6.3 15.4 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SAPS PF04499.15 CDJ47215.1 - 3.3 6.4 15.0 4.5 5.9 15.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 CDJ47215.1 - 3.4 5.7 17.1 4.1 5.4 17.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ureide_permease PF07168.11 CDJ47215.1 - 3.7 6.2 5.8 7.5 5.2 5.8 1.6 1 0 0 1 1 1 0 Ureide permease DUF2370 PF10176.9 CDJ47215.1 - 4.2 7.0 8.8 7.1 6.2 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4175 PF13779.6 CDJ47215.1 - 4.3 5.1 40.1 6.1 4.6 40.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) HCO3_cotransp PF00955.21 CDJ47215.1 - 5.4 5.7 8.8 7.6 5.2 8.8 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF1387 PF07139.11 CDJ47215.1 - 6 6.5 21.9 9 5.9 21.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Band_3_cyto PF07565.13 CDJ47215.1 - 6.3 6.5 18.0 11 5.8 18.0 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Paramyxo_ncap PF00973.19 CDJ47215.1 - 6.4 5.6 13.2 8.5 5.2 13.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Spore_coat_CotO PF14153.6 CDJ47215.1 - 6.5 6.6 27.4 13 5.7 27.4 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Velvet PF11754.8 CDJ47215.1 - 6.7 6.6 22.8 3 7.7 20.7 1.4 2 0 0 2 2 1 0 Velvet factor Ribosomal_60s PF00428.19 CDJ47215.1 - 7.8 7.2 13.3 5.1 7.7 3.8 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAM60A PF15396.6 CDJ47215.1 - 8.3 6.4 19.4 2 8.4 16.0 1.6 2 0 0 2 2 2 0 Protein Family FAM60A DcuA_DcuB PF03605.14 CDJ47215.1 - 8.3 5.2 7.7 2 7.2 4.4 1.6 1 1 1 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter LMBR1 PF04791.16 CDJ47215.1 - 8.9 5.1 11.7 12 4.7 11.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SprA-related PF12118.8 CDJ47215.1 - 9.4 5.3 32.1 19 4.2 32.1 1.5 1 0 0 1 1 1 0 SprA-related family CLN3 PF02487.17 CDJ47215.1 - 9.8 5.1 16.2 15 4.5 16.2 1.2 1 0 0 1 1 1 0 CLN3 protein SCO1-SenC PF02630.14 CDJ47217.1 - 4e-05 23.5 0.0 6.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Spore_IV_A PF09547.10 CDJ47217.1 - 0.01 14.8 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) SWIB PF02201.18 CDJ47217.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 SWIB/MDM2 domain Presenilin PF01080.17 CDJ47219.1 - 0.39 9.4 5.9 0.54 9.0 5.9 1.1 1 0 0 1 1 1 0 Presenilin Activator_LAG-3 PF11498.8 CDJ47219.1 - 1.4 7.9 36.5 2.4 7.0 36.5 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FAM222A PF15258.6 CDJ47219.1 - 4.5 6.3 27.3 0.022 13.9 18.4 1.5 2 0 0 2 2 2 0 Protein family of FAM222A EIF4E-T PF10477.9 CDJ47219.1 - 5.9 5.6 16.6 8.6 5.0 16.6 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Pex14_N PF04695.13 CDJ47219.1 - 9 6.9 26.7 0.68 10.6 15.9 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SUIM_assoc PF16619.5 CDJ47220.1 - 0.019 15.0 6.0 0.019 15.0 6.0 1.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ47220.1 - 0.02 14.5 4.1 0.021 14.4 4.1 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ47220.1 - 0.11 12.5 10.1 0.11 12.4 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ47220.1 - 2 7.4 4.8 2.6 7.1 4.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Ndc1_Nup PF09531.10 CDJ47220.1 - 8.3 5.0 8.8 8.4 4.9 8.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 CDJ47221.1 - 0.0076 15.9 21.3 0.0076 15.9 21.3 4.9 3 2 1 4 4 4 1 Spt20 family SUIM_assoc PF16619.5 CDJ47221.1 - 0.0097 16.0 11.1 0.0097 16.0 11.1 9.0 6 2 1 7 7 7 2 Unstructured region C-term to UIM in Ataxin3 RT_RNaseH_2 PF17919.1 CDJ47222.1 - 3.4e-29 100.8 0.0 9e-29 99.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ47222.1 - 7.9e-28 96.8 0.0 2e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ47222.1 - 2.4e-11 43.9 0.0 7.9e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 CDJ47222.1 - 1.1e-09 38.2 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ47222.1 - 5.8e-08 33.3 0.0 1.2e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ47222.1 - 1e-07 32.4 0.0 2.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ47222.1 - 0.003 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ47222.1 - 0.021 15.2 0.0 0.095 13.0 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease MCM_N PF14551.6 CDJ47223.1 - 0.00075 20.1 0.0 0.071 13.7 0.0 2.1 2 0 0 2 2 2 2 MCM N-terminal domain PRIMA1 PF16101.5 CDJ47224.1 - 3.2 7.8 11.4 1.1 9.3 8.4 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 MCM PF00493.23 CDJ47225.1 - 2.5e-22 79.1 0.0 6e-22 77.8 0.0 1.7 1 1 0 1 1 1 1 MCM P-loop domain SUIM_assoc PF16619.5 CDJ47225.1 - 0.0075 16.3 8.8 0.16 12.1 1.0 2.2 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 AAA_16 PF13191.6 CDJ47225.1 - 0.029 14.8 0.2 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Usp PF00582.26 CDJ47225.1 - 0.13 12.8 0.9 0.69 10.4 0.3 1.9 2 0 0 2 2 2 0 Universal stress protein family RAP1 PF07218.11 CDJ47226.1 - 0.17 10.1 14.0 0.25 9.6 14.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Trp_oprn_chp PF09534.10 CDJ47226.1 - 6.1 6.6 8.1 3.7 7.3 4.4 2.7 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SR-25 PF10500.9 CDJ47228.1 - 6.3e-07 29.2 9.9 6.3e-07 29.2 9.9 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF2339 PF10101.9 CDJ47228.1 - 7.6e-05 21.5 21.2 0.00012 20.9 21.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) TFIIA PF03153.13 CDJ47228.1 - 0.0016 18.5 36.2 0.0023 18.0 36.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF898 PF05987.13 CDJ47228.1 - 0.056 12.5 15.5 0.028 13.5 13.5 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) O-antigen_lig PF13425.6 CDJ47228.1 - 0.23 10.2 3.0 0.99 8.1 0.4 2.1 1 1 1 2 2 2 0 O-antigen ligase like membrane protein TCP PF03634.13 CDJ47228.1 - 0.24 11.9 13.8 0.22 12.1 12.1 1.9 2 0 0 2 2 2 0 TCP family transcription factor RskA PF10099.9 CDJ47228.1 - 0.32 11.3 58.8 7.2e+03 -2.9 9.2 3.8 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Neur_chan_memb PF02932.16 CDJ47228.1 - 8.6 6.3 12.2 16 5.5 10.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RVP_2 PF08284.11 CDJ47229.1 - 4.2e-08 33.1 0.0 8.1e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ47229.1 - 1.3e-07 32.1 0.0 2.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ47229.1 - 5.6e-07 30.0 0.0 1.3e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ47229.1 - 0.014 15.7 0.0 0.031 14.6 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ47229.1 - 0.037 13.8 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease eIF3_p135 PF12807.7 CDJ47230.1 - 4.8e-07 30.0 0.1 1.1e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 DUF3228 PF11539.8 CDJ47232.1 - 6.4e-42 143.3 0.6 1.3e-35 122.7 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3228) DUF1179 PF06678.11 CDJ47232.1 - 0.046 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Ribosomal_L22e PF01776.17 CDJ47233.1 - 5.4e-46 155.5 1.4 6.2e-46 155.3 1.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AMPK1_CBM PF16561.5 CDJ47233.1 - 0.017 15.3 0.0 0.085 13.1 0.0 1.9 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase DEAD PF00270.29 CDJ47235.1 - 8.9e-39 133.0 0.0 1.7e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ47235.1 - 7.3e-17 61.7 0.0 5.7e-16 58.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DSPc PF00782.20 CDJ47235.1 - 5e-09 36.1 0.0 9.1e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ47235.1 - 0.018 15.0 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family CBM_20 PF00686.19 CDJ47235.1 - 0.04 13.8 0.8 0.14 12.1 0.0 2.3 3 0 0 3 3 3 0 Starch binding domain Y_phosphatase PF00102.27 CDJ47235.1 - 0.17 11.5 0.1 0.31 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSS1_SEM1 PF05160.13 CDJ47236.1 - 0.0041 17.1 21.6 0.17 12.0 21.6 2.3 1 1 0 1 1 1 1 DSS1/SEM1 family SPX PF03105.19 CDJ47236.1 - 0.0069 16.4 0.6 0.0077 16.2 0.6 1.0 1 0 0 1 1 1 1 SPX domain VPS13_C PF16909.5 CDJ47237.1 - 3.6e-23 82.3 1.7 5.1e-19 68.7 0.3 3.2 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 CDJ47237.1 - 5.6e-05 23.4 0.0 0.00023 21.5 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 CDJ47237.1 - 0.014 15.5 0.0 0.13 12.4 0.0 2.6 2 1 0 2 2 2 0 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 CDJ47237.1 - 0.094 12.1 0.0 0.54 9.6 0.0 2.2 3 0 0 3 3 3 0 SHR-binding domain of vacuolar-sorting associated protein 13 EPL1 PF10513.9 CDJ47239.1 - 0.0052 17.2 18.8 0.056 13.8 6.5 2.5 2 0 0 2 2 2 2 Enhancer of polycomb-like MecA PF05389.12 CDJ47239.1 - 0.19 11.3 16.0 0.43 10.2 2.3 2.2 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) TCP PF03634.13 CDJ47239.1 - 0.38 11.3 29.7 1.8 9.1 5.0 2.5 2 0 0 2 2 2 0 TCP family transcription factor MMR1 PF08505.10 CDJ47239.1 - 0.45 10.8 33.1 0.078 13.3 12.9 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein PAT1 PF09770.9 CDJ47239.1 - 0.48 8.6 45.3 0.82 7.9 19.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 EIF4E-T PF10477.9 CDJ47239.1 - 0.63 8.8 33.5 0.16 10.7 12.2 2.1 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Velvet PF11754.8 CDJ47239.1 - 1.1 9.2 26.8 2.5 8.0 11.0 2.3 2 0 0 2 2 2 0 Velvet factor SOBP PF15279.6 CDJ47239.1 - 1.3 9.6 27.8 2.3 8.7 13.4 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein TFB6 PF17110.5 CDJ47239.1 - 1.4 8.7 12.0 2.6 7.8 1.1 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF908 PF06012.12 CDJ47239.1 - 1.4 8.3 21.3 1.7 7.9 10.5 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) SID-1_RNA_chan PF13965.6 CDJ47239.1 - 2 6.7 7.2 4.3 5.6 2.1 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 N6_N4_Mtase PF01555.18 CDJ47239.1 - 2.4 7.8 7.1 10 5.7 1.1 2.2 2 0 0 2 2 2 0 DNA methylase DUF572 PF04502.13 CDJ47239.1 - 2.4 7.7 29.8 1.8 8.1 6.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) HNOBA PF07701.14 CDJ47239.1 - 2.7 7.4 16.5 0.56 9.6 1.8 2.2 2 0 0 2 2 2 0 Heme NO binding associated RR_TM4-6 PF06459.12 CDJ47239.1 - 3.4 7.4 30.3 4.5 7.0 7.5 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Activator_LAG-3 PF11498.8 CDJ47239.1 - 3.5 6.5 68.0 0.49 9.3 25.5 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 AAA_23 PF13476.6 CDJ47239.1 - 4.3 7.8 21.8 0.87 10.0 4.0 2.1 2 0 0 2 2 2 0 AAA domain eIF-3_zeta PF05091.12 CDJ47239.1 - 4.5 6.1 36.1 1.9 7.4 11.7 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ47239.1 - 4.6 5.9 35.1 1.9 7.1 16.7 2.2 2 0 0 2 2 2 0 Presenilin Lin-8 PF03353.15 CDJ47239.1 - 4.9 6.6 30.4 1.8 8.0 14.0 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Peptidase_S49_N PF08496.10 CDJ47239.1 - 6 6.9 23.4 8.7 6.4 8.6 2.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FAM60A PF15396.6 CDJ47239.1 - 6.7 6.7 24.8 5 7.1 10.2 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Spt20 PF12090.8 CDJ47239.1 - 9.3 5.8 72.1 4.8 6.7 31.7 2.2 2 0 0 2 2 2 0 Spt20 family SLC12 PF03522.15 CDJ47239.1 - 9.5 5.1 25.6 5.3 5.9 12.2 2.1 2 0 0 2 2 2 0 Solute carrier family 12 CCSAP PF15748.5 CDJ47239.1 - 9.9 6.2 40.4 8.2 6.5 21.1 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated CPSF100_C PF13299.6 CDJ47241.1 - 0.0091 16.2 6.1 0.021 15.0 1.5 2.2 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.13 CDJ47241.1 - 0.013 16.1 14.8 0.013 16.1 14.8 2.7 2 1 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EPL1 PF10513.9 CDJ47241.1 - 0.044 14.2 8.2 0.25 11.7 4.8 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like MecA PF05389.12 CDJ47241.1 - 0.13 11.9 4.2 0.84 9.2 3.0 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) PIG-S PF10510.9 CDJ47241.1 - 0.24 10.2 10.3 0.094 11.5 7.5 1.7 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein Lin-8 PF03353.15 CDJ47241.1 - 0.28 10.7 14.8 0.084 12.4 7.7 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ47241.1 - 0.39 10.7 44.7 0.26 11.2 28.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ47241.1 - 0.85 8.5 13.8 0.64 8.9 11.2 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 CDJ47241.1 - 0.89 9.0 8.4 0.088 12.2 3.0 1.8 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CDJ47241.1 - 2 7.1 12.7 0.44 9.3 6.8 2.0 2 0 0 2 2 2 0 Presenilin RED_N PF07808.13 CDJ47241.1 - 2.1 7.9 14.2 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 RED-like protein N-terminal region DUF3381 PF11861.8 CDJ47241.1 - 3.3 7.5 18.6 1.2 9.0 13.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Hep_59 PF07052.11 CDJ47241.1 - 3.9 8.3 16.4 11 6.8 12.3 2.2 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 AIF_C PF14721.6 CDJ47241.1 - 5.9 7.2 7.7 3.8 7.9 3.9 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1980 PF09323.10 CDJ47241.1 - 7.1 6.5 8.6 5.6 6.8 6.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Ctr PF04145.15 CDJ47241.1 - 8.9 6.9 6.8 4.9 7.8 3.7 2.0 2 0 0 2 2 2 0 Ctr copper transporter family PIP5K PF01504.18 CDJ47241.1 - 9.3 5.4 9.5 1.1e+02 1.8 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase DinB PF05163.12 CDJ47241.1 - 9.9 6.1 18.0 7.5 6.5 11.9 2.2 2 0 0 2 2 2 0 DinB family Spt20 PF12090.8 CDJ47243.1 - 0.0014 18.3 7.1 0.0014 18.3 7.1 12.8 9 3 1 10 10 10 4 Spt20 family Lin-8 PF03353.15 CDJ47244.1 - 6.7 6.2 9.1 9.6 5.7 9.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hydrolase_6 PF13344.6 CDJ47245.1 - 4.4e-29 100.6 0.9 2.7e-28 98.0 0.2 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Isy1 PF06246.12 CDJ47245.1 - 0.00057 19.5 2.9 0.0008 19.1 2.9 1.1 1 0 0 1 1 1 1 Isy1-like splicing family TCP PF03634.13 CDJ47245.1 - 0.0036 17.9 5.8 0.0058 17.2 5.8 1.4 1 0 0 1 1 1 1 TCP family transcription factor TFIIA PF03153.13 CDJ47245.1 - 0.0047 17.0 17.4 0.0067 16.5 17.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ47245.1 - 0.0081 15.0 6.3 0.011 14.6 6.3 1.1 1 0 0 1 1 1 1 Presenilin Hydrolase PF00702.26 CDJ47245.1 - 0.0084 16.4 0.8 0.019 15.3 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rrp15p PF07890.12 CDJ47245.1 - 0.031 14.6 3.3 0.031 14.6 3.3 1.8 3 0 0 3 3 3 0 Rrp15p Ribosomal_L18p PF00861.22 CDJ47245.1 - 0.045 14.1 4.1 0.14 12.6 0.1 2.7 2 1 1 3 3 3 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast SIP PF04954.13 CDJ47245.1 - 0.12 12.8 3.8 0.11 13.0 0.3 2.5 1 1 1 2 2 2 0 Siderophore-interacting protein EcoRI_methylase PF13651.6 CDJ47245.1 - 0.14 11.3 2.4 0.24 10.6 2.3 1.4 1 1 0 1 1 1 0 Adenine-specific methyltransferase EcoRI Neur_chan_memb PF02932.16 CDJ47245.1 - 0.15 12.1 3.5 0.2 11.7 3.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.10 CDJ47245.1 - 0.29 11.2 5.5 0.44 10.6 4.9 1.6 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Ipi1_N PF12333.8 CDJ47245.1 - 0.42 11.2 9.4 0.45 11.1 0.3 2.3 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation XPG_I PF00867.18 CDJ47245.1 - 1.5 9.2 7.1 8.9 6.7 7.1 2.4 1 1 0 1 1 1 0 XPG I-region S36_mt PF10937.8 CDJ47245.1 - 1.6 10.4 9.4 6.6 8.3 0.2 2.6 3 0 0 3 3 2 0 Ribosomal protein S36, mitochondrial DUF2203 PF09969.9 CDJ47245.1 - 1.8 9.3 7.3 2.8 8.7 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) MAP70 PF07058.11 CDJ47245.1 - 3.2 6.4 10.5 4.3 5.9 10.5 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 DUF243 PF03103.17 CDJ47245.1 - 5.7 7.3 12.5 4.6 7.6 3.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF243) DUF5323 PF17257.2 CDJ47246.1 - 1.8e-06 27.7 3.6 4.5e-06 26.4 3.6 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5323) PP2C_2 PF13672.6 CDJ47246.1 - 0.0029 17.3 7.6 0.0029 17.3 7.6 2.4 2 0 0 2 2 2 1 Protein phosphatase 2C Antimicrobial11 PF08106.11 CDJ47246.1 - 0.015 15.3 1.0 0.027 14.5 1.0 1.4 1 0 0 1 1 1 0 Formaecin family Ctf8 PF09696.10 CDJ47246.1 - 0.28 11.5 9.7 0.17 12.2 0.8 2.5 2 0 0 2 2 2 0 Ctf8 Spt20 PF12090.8 CDJ47246.1 - 0.4 10.3 45.0 0.16 11.6 15.4 3.2 3 0 0 3 3 3 0 Spt20 family SR-25 PF10500.9 CDJ47246.1 - 5.2 6.6 24.7 0.11 12.0 15.3 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PRC2_HTH_1 PF18118.1 CDJ47246.1 - 6.6 7.6 7.9 27 5.6 2.2 2.8 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Sin_N PF04801.13 CDJ47247.1 - 0.0015 17.8 10.2 0.0015 17.8 10.2 4.3 2 2 1 3 3 3 1 Sin-like protein conserved region Nha1_C PF08619.10 CDJ47248.1 - 0.019 14.2 14.2 0.029 13.6 14.2 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Band_3_cyto PF07565.13 CDJ47248.1 - 0.24 11.2 3.7 0.3 10.9 3.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF572 PF04502.13 CDJ47248.1 - 0.29 10.7 10.9 0.33 10.5 10.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOG2 PF10428.9 CDJ47248.1 - 0.57 9.3 27.5 0.68 9.1 27.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Miga PF10265.9 CDJ47248.1 - 1 8.3 15.0 1.4 7.8 15.0 1.1 1 0 0 1 1 1 0 Mitoguardin FancD2 PF14631.6 CDJ47248.1 - 1.4 6.2 6.3 2.1 5.6 6.3 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Hid1 PF12722.7 CDJ47248.1 - 1.5 6.9 13.9 1.9 6.5 13.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CDJ47248.1 - 2.1 7.0 12.5 2.4 6.8 12.5 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ47248.1 - 3.2 7.7 5.8 4.3 7.3 5.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Raftlin PF15250.6 CDJ47248.1 - 6.4 5.4 9.7 7.6 5.2 9.7 1.1 1 0 0 1 1 1 0 Raftlin CytochromB561_N PF09786.9 CDJ47248.1 - 6.4 5.6 23.2 8.8 5.2 23.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SLC12 PF03522.15 CDJ47248.1 - 6.7 5.6 7.1 7.8 5.4 7.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 CDJ47248.1 - 7.4 5.2 13.0 9.2 4.9 13.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SOBP PF15279.6 CDJ47248.1 - 7.9 7.0 14.1 11 6.6 14.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Eapp_C PF10238.9 CDJ47248.1 - 8.3 6.5 7.6 20 5.2 7.3 1.7 1 1 0 1 1 1 0 E2F-associated phosphoprotein GREB1 PF15782.5 CDJ47248.1 - 9.4 3.2 21.2 13 2.7 21.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 CDJ47248.1 - 9.5 4.6 14.6 11 4.3 14.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 RVP_2 PF08284.11 CDJ47249.1 - 3.7e-07 30.0 0.0 6.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ47249.1 - 1.7e-06 28.6 0.0 3.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ47249.1 - 4.4e-06 27.2 0.0 8.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ47249.1 - 0.015 15.6 0.0 0.039 14.3 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease SBF2 PF12335.8 CDJ47254.1 - 0.02 14.5 0.1 0.047 13.3 0.1 1.6 1 0 0 1 1 1 0 Myotubularin protein DUF4685 PF15737.5 CDJ47254.1 - 3.8 8.0 7.9 0.16 12.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) SPX PF03105.19 CDJ47255.1 - 3.6 7.4 4.8 5.7 6.8 4.8 1.2 1 0 0 1 1 1 0 SPX domain RNA_pol_Rpo13 PF12136.8 CDJ47256.1 - 0.38 10.7 3.4 7.5 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain SR-25 PF10500.9 CDJ47257.1 - 0.12 11.9 29.5 0.23 11.0 8.7 3.9 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein Tubulin PF00091.25 CDJ47258.1 - 3.1e-33 115.6 1.4 3.5e-33 115.5 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ47258.1 - 4.9e-11 42.9 0.1 8.4e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 CDJ47258.1 - 0.0084 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Cnd1 PF12717.7 CDJ47259.1 - 0.089 12.8 2.1 0.22 11.6 2.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 PBP1_TM PF14812.6 CDJ47259.1 - 1.8 9.0 4.8 3.7 8.0 0.3 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNase_H2_suC PF08615.11 CDJ47259.1 - 7 6.8 13.8 5.1 7.3 0.0 3.2 3 1 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Presenilin PF01080.17 CDJ47260.1 - 5.2 5.7 18.5 5.6 5.6 18.5 1.0 1 0 0 1 1 1 0 Presenilin Stevor PF17410.2 CDJ47261.1 - 0.087 12.4 2.5 0.11 12.1 2.5 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Hc1 PF07432.13 CDJ47261.1 - 0.41 11.0 17.1 0.062 13.7 7.0 2.2 2 0 0 2 2 2 0 Histone H1-like protein Hc1 DUF3253 PF11625.8 CDJ47261.1 - 1.6 9.0 8.6 0.18 12.1 3.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Methyltransf_25 PF13649.6 CDJ47262.1 - 6.6e-13 49.2 0.4 2.9e-12 47.1 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ47262.1 - 4.7e-12 46.4 1.4 8.8e-12 45.5 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ47262.1 - 4.8e-09 36.9 0.0 4.8e-09 36.9 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ47262.1 - 1.3e-08 34.8 0.9 1.3e-08 34.8 0.9 2.5 1 1 1 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ47262.1 - 8.8e-07 28.8 0.6 8.8e-07 28.8 0.6 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ47262.1 - 0.0016 18.4 0.1 0.0016 18.4 0.1 3.8 2 1 1 3 3 2 1 Methyltransferase domain Spt20 PF12090.8 CDJ47262.1 - 0.0021 17.7 11.6 0.0021 17.7 11.6 3.2 3 0 0 3 3 3 1 Spt20 family MTS PF05175.14 CDJ47262.1 - 0.0039 16.7 4.2 0.0042 16.6 1.1 2.5 1 1 1 2 2 2 1 Methyltransferase small domain DUF4366 PF14283.6 CDJ47262.1 - 0.043 13.8 1.2 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Ribosomal_S26e PF01283.19 CDJ47262.1 - 0.11 12.9 0.9 0.23 11.9 0.9 1.5 1 0 0 1 1 1 0 Ribosomal protein S26e AdoMet_MTase PF07757.13 CDJ47262.1 - 0.12 12.8 0.0 0.35 11.2 0.0 1.8 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase RAP1 PF07218.11 CDJ47262.1 - 0.12 10.6 4.3 0.15 10.3 4.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TehB PF03848.14 CDJ47262.1 - 0.14 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB AAA_23 PF13476.6 CDJ47262.1 - 1.1 9.7 26.5 0.27 11.7 6.1 2.1 2 0 0 2 2 2 0 AAA domain PP_kinase_N PF13089.6 CDJ47262.1 - 3.5 8.0 17.5 9.2 6.6 2.5 2.7 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain Secretin_N_2 PF07655.13 CDJ47262.1 - 4.6 7.9 23.8 3.6 8.2 17.8 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain PrmA PF06325.13 CDJ47262.1 - 6.1 6.1 9.8 0.25 10.7 2.2 2.3 2 1 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Coilin_N PF15862.5 CDJ47263.1 - 1.9 8.3 0.0 1.9 8.3 0.0 4.9 5 1 0 5 5 5 0 Coilin N-terminus DAGK_cat PF00781.24 CDJ47264.1 - 1.8e-07 30.8 2.0 4.4e-07 29.6 0.0 2.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 CDJ47264.1 - 1.1e-06 28.4 4.4 1.1e-06 28.4 4.4 2.4 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FA_desaturase PF00487.24 CDJ47264.1 - 0.036 13.9 0.2 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Fatty acid desaturase DUF853 PF05872.12 CDJ47265.1 - 0.43 9.1 16.6 0.44 9.1 16.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RR_TM4-6 PF06459.12 CDJ47265.1 - 0.56 10.0 27.3 0.63 9.8 27.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 CDJ47265.1 - 0.77 8.5 19.6 0.98 8.1 19.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 CDJ47265.1 - 0.77 9.7 18.3 0.86 9.6 18.3 1.0 1 0 0 1 1 1 0 Protein Family FAM60A PRP1_N PF06424.12 CDJ47265.1 - 1 9.7 23.0 1.3 9.5 23.0 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal AUX_IAA PF02309.16 CDJ47265.1 - 3.1 7.6 17.6 3.8 7.3 17.6 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF2052 PF09747.9 CDJ47265.1 - 3.2 7.8 28.5 3.8 7.6 28.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CCSAP PF15748.5 CDJ47265.1 - 4 7.5 32.2 4.6 7.3 32.2 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PNISR PF15996.5 CDJ47265.1 - 4.2 7.6 33.8 5.1 7.3 33.8 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CDC45 PF02724.14 CDJ47265.1 - 4.7 5.4 24.6 5.4 5.2 24.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1387 PF07139.11 CDJ47265.1 - 4.8 6.8 24.7 5.6 6.6 24.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF4045 PF13254.6 CDJ47265.1 - 5.5 6.5 24.0 6.6 6.3 24.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Asp-B-Hydro_N PF05279.11 CDJ47265.1 - 6.4 6.8 25.0 7.6 6.5 25.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LAP1C PF05609.12 CDJ47265.1 - 6.5 5.7 29.3 7.1 5.6 29.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hamartin PF04388.12 CDJ47265.1 - 7 5.2 22.4 7.9 5.0 22.4 1.0 1 0 0 1 1 1 0 Hamartin protein AIF-MLS PF14962.6 CDJ47265.1 - 8.5 6.3 12.3 10 6.0 12.3 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence SLC12 PF03522.15 CDJ47265.1 - 9.5 5.1 28.7 11 4.9 28.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ47265.1 - 9.6 4.8 33.7 11 4.6 33.7 1.0 1 0 0 1 1 1 0 Presenilin Tam41_Mmp37 PF09139.11 CDJ47265.1 - 10 5.5 19.1 12 5.2 19.1 1.1 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Pinin_SDK_memA PF04696.13 CDJ47266.1 - 2.4e-19 69.7 12.4 2.4e-19 69.7 12.4 2.5 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region Aminotran_4 PF01063.19 CDJ47266.1 - 0.12 12.2 0.8 0.21 11.4 0.5 1.6 1 1 0 1 1 1 0 Amino-transferase class IV DUF2439 PF10382.9 CDJ47266.1 - 0.45 10.9 3.8 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) Coilin_N PF15862.5 CDJ47270.1 - 0.91 9.3 11.6 0.036 13.9 2.9 2.1 2 0 0 2 2 2 0 Coilin N-terminus Spt20 PF12090.8 CDJ47270.1 - 1.1 8.8 21.8 0.18 11.4 13.9 2.1 2 0 0 2 2 2 0 Spt20 family Cdh1_DBD_1 PF18196.1 CDJ47270.1 - 6.8 7.0 6.7 0.48 10.8 1.4 1.8 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 NINJA_B PF16136.5 CDJ47271.1 - 3.1 8.2 11.5 3.5 8.0 11.5 1.2 1 0 0 1 1 1 0 Putative nuclear localisation signal RskA PF10099.9 CDJ47271.1 - 5.1 7.3 20.8 5.9 7.1 20.8 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Pex14_N PF04695.13 CDJ47271.1 - 6.3 7.4 18.4 7 7.3 18.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ47271.1 - 8.1 6.3 15.0 7.7 6.4 15.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) IHABP4_N PF16174.5 CDJ47271.1 - 9.8 6.8 20.5 11 6.6 20.5 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal AAA_6 PF12774.7 CDJ47273.1 - 8.3e-145 481.8 0.0 1.8e-144 480.7 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ47273.1 - 7.7e-112 374.3 8.7 7.7e-112 374.3 8.7 5.7 6 1 0 7 7 7 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CDJ47273.1 - 5.5e-86 288.1 0.0 1.8e-85 286.4 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ47273.1 - 9.5e-79 263.6 3.3 9.5e-79 263.6 3.3 2.8 2 0 0 2 2 1 1 ATP-binding dynein motor region DHC_N1 PF08385.12 CDJ47273.1 - 6.8e-73 246.2 27.9 3.5e-52 177.8 4.0 5.3 3 1 2 5 5 5 2 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 CDJ47273.1 - 2.8e-67 225.8 0.6 2.2e-61 206.5 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 CDJ47273.1 - 1.3e-51 175.6 9.1 3.6e-51 174.2 9.1 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CDJ47273.1 - 6.4e-51 172.4 0.0 1.4e-50 171.3 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 CDJ47273.1 - 1.8e-38 132.5 0.0 4.4e-37 128.0 0.0 3.1 2 1 1 3 3 3 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 CDJ47273.1 - 3e-36 124.1 0.0 1.6e-35 121.7 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CDJ47273.1 - 5.9e-23 81.4 0.1 2e-05 24.6 0.0 6.4 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CDJ47273.1 - 6.2e-17 61.7 0.1 2.6e-16 59.7 0.1 2.2 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CDJ47273.1 - 6.9e-17 61.7 0.1 3.6e-16 59.4 0.1 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 CDJ47273.1 - 1.3e-08 35.5 2.8 1.1 9.6 0.0 7.0 6 0 0 6 6 6 1 AAA ATPase domain AAA_22 PF13401.6 CDJ47273.1 - 3.6e-07 30.5 0.9 0.49 10.7 0.0 4.7 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 CDJ47273.1 - 3.4e-05 24.3 2.3 0.32 11.4 0.0 5.4 6 0 0 6 6 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDJ47273.1 - 0.0014 19.2 5.4 0.5 10.9 0.0 5.2 5 0 0 5 5 4 1 AAA domain Sigma54_activat PF00158.26 CDJ47273.1 - 0.0082 15.9 0.0 10 5.8 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 CDJ47273.1 - 0.012 15.0 0.2 3.5 6.9 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_30 PF13604.6 CDJ47273.1 - 0.019 14.7 1.7 3.3 7.4 0.0 3.2 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 CDJ47273.1 - 0.11 12.9 0.0 27 5.2 0.0 3.6 3 0 0 3 3 3 0 RNA helicase RHH_4 PF13467.6 CDJ47273.1 - 0.19 11.6 0.7 4.9 7.1 0.1 3.3 2 0 0 2 2 2 0 Ribbon-helix-helix domain AAA_28 PF13521.6 CDJ47273.1 - 0.21 11.8 3.4 10 6.3 0.0 3.8 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 CDJ47273.1 - 1.3 8.6 4.9 9.3 5.8 0.2 4.4 5 0 0 5 5 4 0 AAA domain ABC1 PF03109.16 CDJ47273.1 - 5.5 7.2 5.8 19 5.5 0.0 4.0 3 0 0 3 3 2 0 ABC1 family SKA2 PF16740.5 CDJ47273.1 - 5.6 6.8 19.4 2.1 8.1 6.1 5.0 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 WD40 PF00400.32 CDJ47274.1 - 8.2e-06 26.5 1.7 0.0015 19.3 0.2 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat tRNA-synt_2b PF00587.25 CDJ47275.1 - 1.3e-25 90.4 0.0 2.1e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) AMP-binding PF00501.28 CDJ47276.1 - 1.4e-16 60.1 0.1 8.7e-10 37.7 0.0 3.3 2 1 0 2 2 2 2 AMP-binding enzyme Apt1 PF10351.9 CDJ47277.1 - 0.34 9.7 17.0 0.12 11.2 8.5 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ47277.1 - 1.6 7.4 7.6 2.9 6.5 0.3 2.1 2 0 0 2 2 2 0 Presenilin Macoilin PF09726.9 CDJ47277.1 - 2.8 6.4 16.1 0.17 10.4 9.0 2.1 2 0 0 2 2 2 0 Macoilin family TCP PF03634.13 CDJ47277.1 - 3.2 8.3 13.2 2.4 8.7 2.5 2.6 2 0 0 2 2 2 0 TCP family transcription factor TFIIA PF03153.13 CDJ47281.1 - 1.6 8.6 18.0 2.1 8.3 18.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ47281.1 - 2.9 7.4 8.0 3.5 7.1 2.7 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Roughex PF06020.11 CDJ47281.1 - 5.2 6.1 9.2 9.5 5.2 9.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ47282.1 - 0.0017 18.0 7.0 0.0017 18.0 7.0 6.0 5 1 1 6 6 6 2 Spt20 family DUF2722 PF10846.8 CDJ47282.1 - 0.0031 16.5 7.2 0.0031 16.5 7.2 5.0 5 0 0 5 5 5 2 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ47282.1 - 0.0065 16.5 0.6 0.0065 16.5 0.6 6.9 5 2 0 5 5 5 3 Unstructured region C-term to UIM in Ataxin3 CBM_48 PF02922.18 CDJ47283.1 - 8.7e-21 74.1 0.0 2.1e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CDJ47283.1 - 8.6e-15 55.1 0.2 4.1e-06 26.6 0.0 2.9 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 CDJ47283.1 - 5.1e-09 36.5 0.1 6.2e-07 29.8 0.0 3.1 2 1 1 3 3 3 1 Alpha amylase, C-terminal all-beta domain PDEase_I PF00233.19 CDJ47284.1 - 1.3e-58 198.5 5.8 2.4e-29 102.7 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Mpt_N PF09176.11 CDJ47284.1 - 0.075 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal GAF_3 PF13492.6 CDJ47284.1 - 0.1 12.9 0.0 0.38 11.1 0.0 1.9 1 0 0 1 1 1 0 GAF domain RCC1_2 PF13540.6 CDJ47285.1 - 5.3e-13 48.4 27.2 1.9e-05 24.4 0.2 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CDJ47285.1 - 1.1e-10 42.0 15.7 0.00066 20.3 1.9 6.8 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat PRK PF00485.18 CDJ47286.1 - 4.5e-06 26.5 0.0 0.0034 17.1 0.0 2.1 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CDJ47286.1 - 8.5e-05 23.1 0.0 0.002 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDJ47286.1 - 0.0032 17.6 0.0 0.092 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CDJ47286.1 - 0.01 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 CDJ47286.1 - 0.017 14.3 0.0 0.39 9.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Cytidylate_kin2 PF13189.6 CDJ47286.1 - 0.072 13.2 0.0 0.96 9.6 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family KTI12 PF08433.10 CDJ47286.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 CDJ47286.1 - 0.099 11.9 0.1 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 CDJ47286.1 - 0.099 13.1 0.1 0.65 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 CDJ47286.1 - 0.11 12.2 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase WD40 PF00400.32 CDJ47287.1 - 3.3e-16 59.4 3.5 0.00012 22.8 0.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ47287.1 - 2.5e-08 34.1 0.0 0.57 10.5 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 CDJ47287.1 - 0.0026 17.2 0.0 0.0065 15.9 0.0 1.7 1 0 0 1 1 1 1 EF hand WD40_like PF17005.5 CDJ47287.1 - 0.029 13.7 0.0 1.3 8.3 0.0 2.0 1 1 2 3 3 3 0 WD40-like domain PQQ_3 PF13570.6 CDJ47287.1 - 0.037 14.5 5.3 1.1 9.8 0.0 4.6 6 0 0 6 6 6 0 PQQ-like domain PQQ PF01011.21 CDJ47287.1 - 0.047 13.6 4.5 54 4.0 0.0 5.0 5 0 0 5 5 5 0 PQQ enzyme repeat Nup160 PF11715.8 CDJ47287.1 - 0.15 10.7 0.0 2.1 6.9 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 NACHT PF05729.12 CDJ47288.1 - 0.0013 18.7 1.9 0.0017 18.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 CDJ47288.1 - 0.0063 16.8 0.0 0.0063 16.8 0.0 3.3 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 CDJ47288.1 - 0.06 12.4 0.0 0.06 12.4 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_23 PF13476.6 CDJ47288.1 - 2.3 8.7 0.0 2.3 8.7 0.0 4.5 4 1 0 4 4 4 0 AAA domain OB_NTP_bind PF07717.16 CDJ47289.1 - 3.4e-16 59.3 0.1 9.3e-16 58.0 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ47289.1 - 1.5e-13 51.0 0.0 4.3e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 CDJ47289.1 - 4.3e-13 49.5 4.6 1.2e-12 48.1 0.1 3.2 3 0 0 3 3 3 1 Helicase associated domain (HA2) RskA PF10099.9 CDJ47289.1 - 1.4e-05 25.4 15.8 0.0017 18.7 12.4 2.9 2 0 0 2 2 2 2 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ47289.1 - 0.018 15.1 27.7 0.03 14.3 11.1 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ47289.1 - 0.08 12.5 18.0 0.018 14.7 10.5 2.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein PH_4 PF15404.6 CDJ47289.1 - 0.46 10.3 2.3 0.44 10.3 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4358 PF14270.6 CDJ47289.1 - 1.3 9.4 5.8 0.45 10.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Med15 PF09606.10 CDJ47289.1 - 1.5 7.4 35.9 0.62 8.7 22.4 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ47289.1 - 2.1 7.9 34.4 0.022 14.4 9.0 2.9 3 0 0 3 3 3 0 Spt20 family CLP_protease PF00574.23 CDJ47290.1 - 7.5e-26 91.1 0.0 5.3e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 Clp protease CNDH2_M PF16869.5 CDJ47293.1 - 2 9.1 9.7 2.4 8.8 9.7 1.2 1 0 0 1 1 1 0 PF16858 TFIIA PF03153.13 CDJ47293.1 - 9 6.2 28.5 12 5.8 28.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4647 PF15504.6 CDJ47293.1 - 10 5.1 20.6 11 5.0 20.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) tRNA-synt_1 PF00133.22 CDJ47294.1 - 7.3e-78 262.3 0.1 9e-78 262.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ47294.1 - 1.2e-31 109.7 0.0 1.2e-14 54.5 0.0 2.7 2 0 0 2 2 2 2 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ47294.1 - 8.6e-07 28.0 0.3 0.012 14.4 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 CDJ47294.1 - 0.00016 21.9 5.4 0.00031 21.0 5.4 1.5 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1b PF00579.25 CDJ47294.1 - 0.0025 17.2 0.1 0.0046 16.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pro_racemase PF05544.11 CDJ47295.1 - 2.3 7.2 5.7 3.6 6.5 4.8 1.6 2 0 0 2 2 2 0 Proline racemase Membralin PF09746.9 CDJ47295.1 - 9.2 5.2 17.0 5.9 5.8 15.6 1.3 1 1 0 1 1 1 0 Tumour-associated protein SR-25 PF10500.9 CDJ47296.1 - 0.0026 17.4 6.0 0.0026 17.4 6.0 7.2 5 2 1 6 6 6 3 Nuclear RNA-splicing-associated protein Het-C PF07217.11 CDJ47296.1 - 0.4 9.1 5.2 1.1 7.8 5.2 1.7 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF3290 PF11694.8 CDJ47296.1 - 0.93 9.5 0.0 0.93 9.5 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3290) PAT1 PF09770.9 CDJ47297.1 - 3.7e-06 25.5 39.3 3.7e-06 25.5 39.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF2828 PF11443.8 CDJ47297.1 - 0.0048 15.1 20.8 0.0062 14.7 20.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) SID-1_RNA_chan PF13965.6 CDJ47297.1 - 0.01 14.3 8.7 0.013 13.9 8.7 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RIFIN PF02009.16 CDJ47297.1 - 0.025 14.5 25.2 0.032 14.1 25.2 1.3 1 0 0 1 1 1 0 Rifin LMBR1 PF04791.16 CDJ47297.1 - 2.8 6.8 12.8 2.3 7.0 12.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 CDJ47297.1 - 3.1 7.3 32.9 4 6.9 32.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SAPS PF04499.15 CDJ47297.1 - 3.5 6.3 25.8 4.8 5.8 25.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop53 PF07767.11 CDJ47297.1 - 3.6 6.9 49.0 4.8 6.5 49.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Utp14 PF04615.13 CDJ47298.1 - 0.0057 15.3 42.1 0.0029 16.3 19.6 2.1 2 0 0 2 2 2 2 Utp14 protein Arginase PF00491.21 CDJ47298.1 - 0.47 9.9 0.0 0.47 9.9 0.0 2.6 3 1 0 3 3 3 0 Arginase family SARAF PF06682.12 CDJ47298.1 - 5.1 6.6 44.2 0.69 9.5 2.3 3.3 3 1 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1418 PF07214.12 CDJ47299.1 - 8.2 6.4 10.8 0.27 11.1 0.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) Fusion_gly PF00523.18 CDJ47300.1 - 1.1 7.4 3.7 1.3 7.2 3.7 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Melibiase_2 PF16499.5 CDJ47302.1 - 0.00013 21.2 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A SR-25 PF10500.9 CDJ47302.1 - 0.0014 18.3 23.2 0.0014 18.3 23.2 2.9 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ47302.1 - 0.0048 17.2 26.5 0.0048 17.2 26.5 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF755) Helicase_C PF00271.31 CDJ47303.1 - 1.4e-18 67.2 0.0 2.2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CDJ47303.1 - 0.0061 15.8 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PPP4R2 PF09184.11 CDJ47303.1 - 0.23 11.0 13.1 0.26 10.8 13.1 1.2 1 0 0 1 1 1 0 PPP4R2 PAP1 PF08601.10 CDJ47303.1 - 0.25 11.0 26.3 0.27 10.9 26.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Guanylate_cyc PF00211.20 CDJ47304.1 - 5.5e-69 231.5 0.0 1.9e-33 115.6 0.0 3.1 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain E1-E2_ATPase PF00122.20 CDJ47305.1 - 0.017 14.7 0.1 0.28 10.7 0.0 2.9 2 1 0 2 2 2 0 E1-E2 ATPase Hydrolase PF00702.26 CDJ47305.1 - 0.22 11.8 0.2 4.8 7.4 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase EGF_CA PF07645.15 CDJ47306.1 - 4.5e-09 36.4 7.8 1e-08 35.2 7.8 1.6 1 0 0 1 1 1 1 Calcium-binding EGF domain Peptidase_C11 PF03415.14 CDJ47306.1 - 3.5e-07 30.0 0.0 5.7e-05 22.7 0.0 3.0 3 0 0 3 3 3 1 Clostripain family Notch PF00066.17 CDJ47306.1 - 8.8e-06 26.1 3.1 2.1e-05 24.9 3.1 1.6 1 0 0 1 1 1 1 LNR domain EGF_3 PF12947.7 CDJ47306.1 - 0.0013 18.9 8.5 0.0013 18.9 8.5 3.0 3 0 0 3 3 3 1 EGF domain FXa_inhibition PF14670.6 CDJ47306.1 - 0.0032 17.7 8.3 0.0032 17.7 8.3 2.5 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF PF00008.27 CDJ47306.1 - 0.0036 17.6 2.6 0.0036 17.6 2.6 2.7 2 0 0 2 2 2 1 EGF-like domain cEGF PF12662.7 CDJ47306.1 - 0.016 15.1 8.8 0.033 14.1 4.6 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like hEGF PF12661.7 CDJ47306.1 - 0.019 15.6 2.8 0.019 15.6 2.8 2.5 2 0 0 2 2 2 0 Human growth factor-like EGF DUF5622 PF18533.1 CDJ47307.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5622) RNase_Zc3h12a PF11977.8 CDJ47308.1 - 1.9e-05 24.5 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain T6SS_TssG PF06996.11 CDJ47308.1 - 0.055 12.7 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion, TssG Trypan_PARP PF05887.11 CDJ47309.1 - 0.0022 18.0 22.3 0.0022 18.0 22.3 2.6 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) DrrA_P4M PF14860.6 CDJ47309.1 - 0.082 12.8 0.1 0.66 9.9 0.1 2.3 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain CBM_20 PF00686.19 CDJ47310.1 - 4.6e-13 48.9 0.0 3.8e-12 46.0 0.0 2.2 1 1 0 1 1 1 1 Starch binding domain FtsJ PF01728.19 CDJ47311.1 - 7.6e-09 35.9 0.1 1.1e-06 28.8 0.0 2.6 3 0 0 3 3 3 1 FtsJ-like methyltransferase PAT1 PF09770.9 CDJ47311.1 - 0.0017 16.7 10.3 0.0017 16.7 10.3 1.9 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 RskA PF10099.9 CDJ47311.1 - 0.016 15.5 1.1 0.016 15.5 1.1 6.0 2 2 3 5 5 2 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ47311.1 - 0.085 12.9 0.1 0.085 12.9 0.1 6.4 6 1 0 6 6 4 0 Unstructured region C-term to UIM in Ataxin3 SID-1_RNA_chan PF13965.6 CDJ47311.1 - 0.6 8.5 3.2 4.6 5.5 0.8 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ47311.1 - 0.81 9.7 10.7 0.99 9.4 4.9 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DAG_kinase_N PF14513.6 CDJ47311.1 - 1.2 9.3 12.3 2.4 8.4 6.0 2.8 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus FAM60A PF15396.6 CDJ47311.1 - 2.4 8.1 11.9 27 4.7 9.2 2.5 2 0 0 2 2 2 0 Protein Family FAM60A SAPS PF04499.15 CDJ47311.1 - 2.5 6.8 12.7 2.1 7.0 5.5 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 CDJ47311.1 - 2.6 6.8 8.7 0.43 9.4 0.9 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF913 PF06025.12 CDJ47311.1 - 4.7 6.1 11.8 0.58 9.1 5.9 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 CDJ47311.1 - 7.1 6.7 15.5 0.049 13.8 2.3 2.7 2 1 0 2 2 2 0 DDHD domain MutS_V PF00488.21 CDJ47312.1 - 0.014 15.5 0.0 0.044 13.8 0.0 1.9 1 0 0 1 1 1 0 MutS domain V PE_PPE_C PF12484.8 CDJ47312.1 - 0.58 11.1 15.2 2.1 9.3 15.2 1.9 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal NPR3 PF03666.13 CDJ47312.1 - 0.72 8.6 40.5 0.18 10.6 17.7 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SUIM_assoc PF16619.5 CDJ47312.1 - 4.3 7.5 0.0 4.3 7.5 0.0 9.4 2 2 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 MFS_1 PF07690.16 CDJ47313.1 - 1.1e-11 44.3 0.0 5.3e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ47313.1 - 1.1e-08 34.4 13.4 2e-08 33.5 12.0 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter SpoIIIAH PF12685.7 CDJ47313.1 - 0.0034 17.2 1.6 0.0034 17.2 1.6 4.0 3 1 0 3 3 3 1 SpoIIIAH-like protein ABC2_membrane_2 PF12679.7 CDJ47313.1 - 0.0045 16.3 0.1 0.0045 16.3 0.1 3.0 3 1 0 3 3 3 1 ABC-2 family transporter protein Pex14_N PF04695.13 CDJ47313.1 - 0.0061 17.2 6.7 0.0061 17.2 6.7 4.7 2 1 2 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.9 CDJ47313.1 - 0.0061 16.2 14.9 0.0061 16.2 14.9 4.2 3 1 0 4 4 4 1 Nuclear RNA-splicing-associated protein Scs3p PF10261.9 CDJ47313.1 - 0.012 15.2 0.1 0.012 15.2 0.1 2.5 3 0 0 3 3 3 0 Inositol phospholipid synthesis and fat-storage-inducing TM Gaa1 PF04114.14 CDJ47313.1 - 1.5 7.7 6.6 1.3 7.9 0.3 2.4 1 1 0 2 2 2 0 Gaa1-like, GPI transamidase component MORN PF02493.20 CDJ47314.1 - 0.0092 15.8 1.6 0.2 11.6 0.1 3.4 3 0 0 3 3 3 1 MORN repeat DUF4667 PF15700.5 CDJ47314.1 - 0.81 9.7 10.5 2.6 8.1 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ47314.1 - 1.7 8.5 20.3 0.058 13.4 11.7 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ47314.1 - 3.3 6.5 19.0 0.025 13.5 10.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 CDJ47314.1 - 5 6.0 6.4 7.7 5.4 6.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EPL1 PF10513.9 CDJ47314.1 - 5.7 7.3 6.5 5.7 7.3 1.8 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Apt1 PF10351.9 CDJ47315.1 - 1.9 7.3 5.9 1.8 7.4 5.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1635 PF07795.11 CDJ47315.1 - 1.9 8.3 8.1 3 7.7 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Sec1 PF00995.23 CDJ47316.1 - 8.7e-21 74.8 0.1 1.1e-20 74.5 0.1 1.1 1 0 0 1 1 1 1 Sec1 family Spt20 PF12090.8 CDJ47316.1 - 0.0004 20.1 1.1 0.00041 20.0 1.1 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ47316.1 - 0.0022 17.0 0.6 0.0024 16.9 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Glyco_transf_4 PF13439.6 CDJ47316.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase Family 4 7tm_2 PF00002.24 CDJ47316.1 - 0.13 11.5 1.2 0.15 11.3 1.2 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) 7TM_GPCR_Sru PF10322.9 CDJ47316.1 - 0.5 9.6 1.8 0.5 9.6 0.6 1.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru EphA2_TM PF14575.6 CDJ47316.1 - 0.54 11.2 2.9 0.75 10.7 2.9 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RskA PF10099.9 CDJ47316.1 - 1.8 8.9 4.9 6.2 7.1 1.3 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Hist_deacetyl PF00850.19 CDJ47317.1 - 7.3e-08 32.2 0.0 7.3e-08 32.2 0.0 3.1 1 1 2 3 3 3 1 Histone deacetylase domain GAGA_bind PF06217.12 CDJ47317.1 - 0.1 12.9 10.5 0.14 12.4 10.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Hamartin PF04388.12 CDJ47317.1 - 0.19 10.4 17.3 0.24 10.0 17.3 1.0 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 CDJ47317.1 - 0.36 9.4 15.5 0.45 9.1 15.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 CDJ47317.1 - 7.3 6.6 15.3 12 5.8 15.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CDJ47318.1 - 0.00013 21.3 27.3 0.0025 17.1 0.0 2.4 2 0 0 2 2 2 1 ZIP Zinc transporter V_ATPase_I PF01496.19 CDJ47318.1 - 0.00016 19.8 11.0 0.00016 19.8 11.0 2.7 2 1 0 2 2 1 1 V-type ATPase 116kDa subunit family MAP17 PF15807.5 CDJ47318.1 - 0.00086 19.5 0.2 0.00086 19.5 0.2 3.3 2 1 0 2 2 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SAGA-Tad1 PF12767.7 CDJ47318.1 - 0.00098 18.9 14.4 0.00098 18.9 14.4 2.6 3 0 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF4834 PF16118.5 CDJ47318.1 - 0.0019 19.1 9.2 0.0019 19.1 9.2 4.9 3 2 0 3 3 2 1 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ47318.1 - 0.0033 17.1 2.1 0.0033 17.1 2.1 3.4 2 1 1 3 3 1 1 FAM176 family Peptidase_S49_N PF08496.10 CDJ47318.1 - 0.0035 17.4 4.1 0.0035 17.4 4.1 3.3 2 1 1 3 3 1 1 Peptidase family S49 N-terminal Afi1 PF07792.12 CDJ47318.1 - 0.0044 17.5 0.3 0.0044 17.5 0.3 3.4 2 1 1 3 3 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking CLN3 PF02487.17 CDJ47318.1 - 0.0047 16.0 4.1 0.0047 16.0 4.1 3.1 2 1 0 2 2 1 1 CLN3 protein SID-1_RNA_chan PF13965.6 CDJ47318.1 - 0.012 14.0 0.8 0.012 14.0 0.8 2.7 2 1 0 2 2 1 0 dsRNA-gated channel SID-1 MMM1 PF10296.9 CDJ47318.1 - 0.013 14.6 1.5 0.013 14.6 1.5 3.3 2 1 0 2 2 1 0 Maintenance of mitochondrial morphology protein 1 SARAF PF06682.12 CDJ47318.1 - 0.014 15.0 3.6 0.014 15.0 3.6 3.9 3 1 0 3 3 2 0 SOCE-associated regulatory factor of calcium homoeostasis Ctr PF04145.15 CDJ47318.1 - 0.015 16.0 2.4 0.015 16.0 2.4 3.9 3 1 0 3 3 2 0 Ctr copper transporter family Tetraspanin PF00335.20 CDJ47318.1 - 0.02 14.6 0.4 0.02 14.6 0.4 2.5 2 1 0 2 2 1 0 Tetraspanin family DUF4446 PF14584.6 CDJ47318.1 - 0.043 13.8 0.9 0.043 13.8 0.9 3.1 2 1 1 3 3 1 0 Protein of unknown function (DUF4446) 7tm_3 PF00003.22 CDJ47318.1 - 0.083 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Macoilin PF09726.9 CDJ47318.1 - 0.24 9.9 50.1 0.8 8.2 8.1 2.1 2 0 0 2 2 2 0 Macoilin family Rib_5-P_isom_A PF06026.14 CDJ47318.1 - 0.25 10.9 2.4 0.5 9.9 2.4 1.4 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) AAA_11 PF13086.6 CDJ47318.1 - 0.32 10.7 45.9 1.4 8.7 5.2 2.3 2 0 0 2 2 2 0 AAA domain DUF4220 PF13968.6 CDJ47318.1 - 0.35 10.2 2.6 8.6 5.6 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) Acatn PF13000.7 CDJ47318.1 - 0.71 8.3 0.0 0.71 8.3 0.0 3.0 2 1 1 3 3 1 0 Acetyl-coenzyme A transporter 1 Exonuc_VII_L PF02601.15 CDJ47318.1 - 1.6 8.2 50.8 0.38 10.3 34.0 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit SLC12 PF03522.15 CDJ47318.1 - 2.4 7.1 59.1 0.36 9.8 8.0 2.2 2 0 0 2 2 2 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ47318.1 - 2.5 8.1 48.2 0.3 11.1 7.9 2.8 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Mpp10 PF04006.12 CDJ47318.1 - 3.4 6.0 57.4 0.33 9.3 36.8 2.1 2 0 0 2 2 2 0 Mpp10 protein DUF4746 PF15928.5 CDJ47318.1 - 6.7 6.0 43.1 0.49 9.8 23.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Endonuclease_NS PF01223.23 CDJ47319.1 - 1.7e-06 28.0 0.0 3e-05 24.0 0.0 2.0 2 0 0 2 2 2 2 DNA/RNA non-specific endonuclease DUF2722 PF10846.8 CDJ47321.1 - 0.0086 15.1 19.0 0.017 14.1 5.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ47321.1 - 0.019 15.0 58.8 0.39 10.6 13.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Helicase_RecD PF05127.14 CDJ47321.1 - 1.1 9.1 12.5 0.18 11.7 5.4 2.7 2 0 0 2 2 2 0 Helicase SpoVR PF04293.13 CDJ47321.1 - 2.1 6.9 6.8 1.9 7.1 0.1 2.1 2 0 0 2 2 2 0 SpoVR like protein MMR1 PF08505.10 CDJ47321.1 - 2.2 8.5 18.0 0.44 10.8 6.5 2.4 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein FGAR-AT_N PF18076.1 CDJ47321.1 - 4.9 7.2 7.6 2.5 8.1 1.3 2.6 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase N-terminal TERB2 PF15101.6 CDJ47321.1 - 5.7 6.9 16.4 9.3 6.2 7.0 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 RAB3GAP2_N PF14655.6 CDJ47321.1 - 8.4 5.5 15.5 5.3 6.2 4.1 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TCP PF03634.13 CDJ47322.1 - 0.0075 16.8 4.1 0.0075 16.8 4.1 3.9 3 1 0 3 3 3 1 TCP family transcription factor O-antigen_lig PF13425.6 CDJ47322.1 - 1.3 7.7 11.3 2.4 6.8 0.1 2.3 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Utp11 PF03998.13 CDJ47322.1 - 2.3 8.1 42.9 5.7 6.8 3.6 2.4 2 0 0 2 2 2 0 Utp11 protein Utp14 PF04615.13 CDJ47322.1 - 4.8 5.6 38.3 0.34 9.4 31.0 2.1 2 0 0 2 2 2 0 Utp14 protein RR_TM4-6 PF06459.12 CDJ47322.1 - 9.7 5.9 51.1 0.37 10.6 21.0 3.3 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 AdoHcyase_NAD PF00670.21 CDJ47324.1 - 2.1e-51 174.2 2.8 4.1e-51 173.3 2.8 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 CDJ47324.1 - 2.2e-36 125.5 0.0 6.9e-21 74.7 0.0 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.19 CDJ47324.1 - 4.1e-06 26.3 0.0 6.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CDJ47324.1 - 0.00038 20.1 1.3 0.00041 20.0 0.1 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CDJ47324.1 - 0.058 13.7 3.3 0.063 13.5 0.2 2.2 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 CDJ47324.1 - 0.07 13.2 0.1 0.23 11.5 0.1 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltrn_RNA_3 PF02598.17 CDJ47325.1 - 3.7e-17 62.8 0.0 5.9e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methyltransferase SR-25 PF10500.9 CDJ47326.1 - 0.0024 17.5 3.7 0.0024 17.5 3.7 5.8 5 1 1 7 7 7 2 Nuclear RNA-splicing-associated protein BTB_2 PF02214.22 CDJ47326.1 - 0.012 16.0 0.0 0.039 14.3 0.0 1.9 1 0 0 1 1 1 0 BTB/POZ domain Ufd2P_core PF10408.9 CDJ47326.1 - 0.41 9.2 0.0 0.41 9.2 0.0 7.1 5 1 1 6 6 6 0 Ubiquitin elongating factor core HSP20 PF00011.21 CDJ47328.1 - 2.4e-10 40.4 0.0 4.3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ47328.1 - 0.0017 17.9 0.0 0.0064 16.0 0.0 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA ALP_N PF17989.1 CDJ47329.1 - 0.13 12.4 0.2 0.58 10.3 0.2 2.1 1 0 0 1 1 1 0 Actin like proteins N terminal domain DUF4252 PF14060.6 CDJ47329.1 - 0.18 11.7 1.3 0.64 9.9 1.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) 7TM_GPCR_Srv PF10323.9 CDJ47329.1 - 1 8.7 3.5 0.5 9.7 0.8 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DIE2_ALG10 PF04922.12 CDJ47329.1 - 1.1 8.4 2.9 2.3 7.4 2.9 1.4 1 0 0 1 1 1 0 DIE2/ALG10 family DUF4131 PF13567.6 CDJ47329.1 - 1.9 8.1 5.4 0.88 9.2 1.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Thg1C PF14413.6 CDJ47330.1 - 7.9 6.7 9.0 17 5.6 2.3 2.5 2 0 0 2 2 2 0 Thg1 C terminal domain RAP1 PF07218.11 CDJ47332.1 - 0.00021 19.8 12.5 0.00021 19.8 12.5 3.4 3 1 0 4 4 4 1 Rhoptry-associated protein 1 (RAP-1) NAM-associated PF14303.6 CDJ47332.1 - 0.0082 16.9 9.7 0.0082 16.9 9.7 5.2 3 2 2 5 5 5 1 No apical meristem-associated C-terminal domain Ribosomal_60s PF00428.19 CDJ47333.1 - 0.013 16.1 14.4 0.013 16.1 14.4 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein OmpH PF03938.14 CDJ47333.1 - 1.4 9.2 23.2 0.09 13.1 15.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Presenilin PF01080.17 CDJ47333.1 - 5.9 5.5 6.7 8.2 5.1 6.7 1.2 1 0 0 1 1 1 0 Presenilin DUF4207 PF13904.6 CDJ47333.1 - 7.9 6.1 20.1 0.24 11.1 13.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) SDA1 PF05285.12 CDJ47334.1 - 2.4 7.5 20.9 2.6 7.4 20.9 1.0 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CDJ47334.1 - 2.8 6.1 19.5 3.4 5.8 19.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Peroxin-3 PF04882.12 CDJ47334.1 - 4.6 6.1 24.6 5.8 5.8 24.6 1.1 1 0 0 1 1 1 0 Peroxin-3 Nop14 PF04147.12 CDJ47334.1 - 6.1 4.9 20.0 7 4.7 20.0 1.0 1 0 0 1 1 1 0 Nop14-like family SRP-alpha_N PF04086.13 CDJ47334.1 - 7.7 6.3 22.9 9.2 6.1 22.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SR-25 PF10500.9 CDJ47335.1 - 0.0083 15.8 25.9 0.0083 15.8 25.9 2.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein SprA-related PF12118.8 CDJ47335.1 - 0.12 11.5 44.0 0.13 11.4 44.0 1.0 1 0 0 1 1 1 0 SprA-related family Methyltransf_12 PF08242.12 CDJ47335.1 - 0.13 13.0 1.2 0.17 12.6 1.2 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4175 PF13779.6 CDJ47335.1 - 0.22 9.4 24.2 0.21 9.5 24.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4407 PF14362.6 CDJ47335.1 - 0.3 10.4 9.5 0.28 10.5 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ47335.1 - 0.32 10.9 34.2 0.41 10.6 34.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ47335.1 - 0.71 8.8 18.0 0.66 8.9 18.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DcuA_DcuB PF03605.14 CDJ47335.1 - 1.4 7.7 3.3 1.6 7.6 3.3 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter V_ATPase_I PF01496.19 CDJ47335.1 - 2.8 5.7 12.9 2.7 5.8 12.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 CDJ47335.1 - 5 6.9 18.2 5.9 6.6 18.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2232 PF09991.9 CDJ47335.1 - 6.3 5.9 5.6 7.2 5.7 5.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SseC PF04888.12 CDJ47335.1 - 6.6 6.2 21.7 11 5.5 21.7 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ASD2 PF08687.11 CDJ47335.1 - 9.2 5.7 19.9 13 5.2 19.9 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 SDF PF00375.18 CDJ47336.1 - 0.0007 18.7 0.1 0.00083 18.5 0.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CBP_BcsG PF11658.8 CDJ47336.1 - 0.0026 16.2 7.7 0.0032 16.0 7.7 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG SARAF PF06682.12 CDJ47336.1 - 0.0059 16.3 10.4 0.0074 16.0 10.4 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Trp_oprn_chp PF09534.10 CDJ47336.1 - 0.0097 15.7 3.3 0.012 15.4 3.3 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PIP5K PF01504.18 CDJ47336.1 - 0.01 15.1 6.3 0.015 14.5 6.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase RR_TM4-6 PF06459.12 CDJ47336.1 - 0.027 14.3 8.0 0.026 14.4 8.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2992 PF11208.8 CDJ47336.1 - 0.058 13.6 14.3 0.065 13.5 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) RskA PF10099.9 CDJ47336.1 - 0.058 13.7 21.1 0.071 13.4 21.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA ADP_ribosyl_GH PF03747.14 CDJ47336.1 - 0.12 12.1 3.4 0.13 12.0 3.4 1.0 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Serinc PF03348.15 CDJ47336.1 - 0.14 11.0 10.9 0.17 10.8 10.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Velvet PF11754.8 CDJ47336.1 - 0.22 11.4 16.9 0.25 11.3 16.9 1.0 1 0 0 1 1 1 0 Velvet factor SprA-related PF12118.8 CDJ47336.1 - 0.27 10.3 32.7 0.31 10.1 32.7 1.0 1 0 0 1 1 1 0 SprA-related family O-antigen_lig PF13425.6 CDJ47336.1 - 0.31 9.8 2.1 0.38 9.5 2.1 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Shisa PF13908.6 CDJ47336.1 - 0.34 11.1 14.7 0.4 10.9 14.7 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3682 PF12446.8 CDJ47336.1 - 0.48 10.9 28.5 0.66 10.5 28.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Adeno_PV PF03910.13 CDJ47336.1 - 0.53 8.9 6.4 0.54 8.9 6.4 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV V_ATPase_I PF01496.19 CDJ47336.1 - 0.53 8.1 10.5 0.58 8.0 10.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ47336.1 - 0.54 9.0 17.6 0.63 8.7 17.6 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ47336.1 - 0.55 10.2 39.7 0.6 10.1 39.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ACC_epsilon PF13822.6 CDJ47336.1 - 0.71 10.6 15.2 1.2 9.9 15.2 1.5 1 1 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Spore_coat_CotO PF14153.6 CDJ47336.1 - 0.76 9.7 20.0 0.84 9.5 20.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Ribosomal_60s PF00428.19 CDJ47336.1 - 0.8 10.3 6.7 1.1 9.9 6.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Suf PF05843.14 CDJ47336.1 - 0.94 9.4 20.4 1 9.2 20.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SWI-SNF_Ssr4 PF08549.10 CDJ47336.1 - 1.5 7.3 21.0 1.7 7.2 21.0 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) EOS1 PF12326.8 CDJ47336.1 - 1.6 8.6 9.2 2.1 8.3 9.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein Zip PF02535.22 CDJ47336.1 - 1.7 7.8 5.5 1.8 7.7 5.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter LD_cluster2 PF18163.1 CDJ47336.1 - 1.7 8.1 8.6 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 SLOG cluster2 Dicty_REP PF05086.12 CDJ47336.1 - 2.1 6.2 15.5 2.2 6.2 15.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BAF1_ABF1 PF04684.13 CDJ47336.1 - 3.9 6.4 18.2 4.5 6.2 18.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Neur_chan_memb PF02932.16 CDJ47336.1 - 4 7.4 10.2 4.8 7.2 10.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region XRN_M PF17846.1 CDJ47336.1 - 5.3 5.9 10.0 5.5 5.8 10.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DDHD PF02862.17 CDJ47336.1 - 5.5 7.1 15.1 7 6.7 15.1 1.2 1 0 0 1 1 1 0 DDHD domain FAM199X PF15814.5 CDJ47336.1 - 6.4 5.7 17.7 7.5 5.5 17.7 1.0 1 0 0 1 1 1 0 Protein family FAM199X R_equi_Vir PF05526.11 CDJ47336.1 - 6.9 6.5 12.2 8.3 6.2 12.2 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein EIF4E-T PF10477.9 CDJ47336.1 - 7.3 5.3 24.2 7.8 5.2 24.2 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RXLR PF16810.5 CDJ47336.1 - 7.5 7.0 13.0 7.3 7.0 6.6 2.0 1 1 1 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Wzz PF02706.15 CDJ47336.1 - 8.9 6.7 11.7 16 5.9 11.7 1.4 1 0 0 1 1 1 0 Chain length determinant protein PRCC PF10253.9 CDJ47337.1 - 0.012 16.4 57.4 0.48 11.2 20.1 2.4 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Pex14_N PF04695.13 CDJ47339.1 - 0.0011 19.7 19.7 0.0011 19.7 19.7 1.6 2 0 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ47339.1 - 0.0034 17.5 31.5 0.0047 17.0 31.5 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit VIT1 PF01988.19 CDJ47339.1 - 0.009 15.9 2.9 0.013 15.4 2.9 1.3 1 0 0 1 1 1 1 VIT family MMR1 PF08505.10 CDJ47339.1 - 0.027 14.8 16.2 0.031 14.6 16.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FTZ PF03867.14 CDJ47339.1 - 0.11 12.1 17.4 0.16 11.5 17.4 1.4 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region NPR3 PF03666.13 CDJ47339.1 - 0.13 11.1 14.7 0.12 11.1 14.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mitofilin PF09731.9 CDJ47339.1 - 0.16 10.8 24.5 0.17 10.7 24.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MDM10 PF12519.8 CDJ47339.1 - 0.31 9.8 7.6 0.3 9.9 7.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4813 PF16072.5 CDJ47339.1 - 0.36 10.4 23.5 0.44 10.2 23.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) SAPS PF04499.15 CDJ47339.1 - 0.39 9.5 13.6 0.5 9.1 13.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Otopetrin PF03189.13 CDJ47339.1 - 0.5 9.1 3.9 0.49 9.2 3.9 1.2 1 0 0 1 1 1 0 Otopetrin Peptidase_S64 PF08192.11 CDJ47339.1 - 0.69 8.3 9.3 0.63 8.5 9.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.9 CDJ47339.1 - 0.71 8.1 26.3 0.83 7.8 26.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0560 PF10577.9 CDJ47339.1 - 1.1 7.7 19.3 1.5 7.2 19.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Plasmodium_Vir PF05795.11 CDJ47339.1 - 1.1 8.5 8.7 1.3 8.3 8.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.16 CDJ47339.1 - 1.3 9.0 13.5 2.1 8.3 13.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ47339.1 - 1.7 7.4 11.4 2.1 7.1 11.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Lin-8 PF03353.15 CDJ47339.1 - 1.8 8.1 18.4 2.4 7.7 18.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 CDJ47339.1 - 1.9 5.5 17.7 1.8 5.6 17.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer OATP PF03137.20 CDJ47339.1 - 2.2 6.4 5.2 3 6.0 5.2 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CLN3 PF02487.17 CDJ47339.1 - 2.5 7.0 8.8 2.9 6.8 8.8 1.3 1 0 0 1 1 1 0 CLN3 protein Activator_LAG-3 PF11498.8 CDJ47339.1 - 2.6 6.9 51.8 3.7 6.4 51.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF572 PF04502.13 CDJ47339.1 - 3 7.4 20.2 4.2 6.9 20.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Med15 PF09606.10 CDJ47339.1 - 3 6.4 37.5 3.3 6.3 37.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ndc1_Nup PF09531.10 CDJ47339.1 - 3.2 6.3 16.3 3.5 6.2 16.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Membralin PF09746.9 CDJ47339.1 - 4.1 6.3 6.6 4.9 6.1 6.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein NST1 PF13945.6 CDJ47339.1 - 5.1 7.2 27.2 0.13 12.3 17.8 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator Pannexin_like PF12534.8 CDJ47339.1 - 5.8 5.9 10.0 8.9 5.3 10.0 1.4 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF913 PF06025.12 CDJ47339.1 - 6.7 5.6 10.0 8.5 5.2 10.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ABC2_membrane_2 PF12679.7 CDJ47339.1 - 7.5 5.7 7.3 11 5.3 7.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Caldesmon PF02029.15 CDJ47340.1 - 1.3 7.7 68.1 1.8 7.3 68.1 1.1 1 0 0 1 1 1 0 Caldesmon DUF4775 PF16001.5 CDJ47340.1 - 2.7 7.3 65.3 5.1 6.4 65.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4775) MCM_bind PF09739.9 CDJ47341.1 - 6.7 5.0 8.9 8.7 4.7 8.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CDC45 PF02724.14 CDJ47341.1 - 7.2 4.8 13.0 10 4.3 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5527 PF17665.1 CDJ47342.1 - 0.079 12.5 2.0 0.12 11.9 2.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Med3 PF11593.8 CDJ47342.1 - 0.23 10.6 8.6 0.29 10.3 8.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SUIM_assoc PF16619.5 CDJ47342.1 - 0.63 10.2 12.8 0.058 13.5 5.9 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CDJ47342.1 - 4.7 7.9 11.0 9.3 6.9 9.5 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ47343.1 - 0.00011 21.9 31.6 0.0038 16.9 3.4 2.4 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ47343.1 - 0.01 14.8 1.1 0.01 14.8 1.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2722) FLYWCH_u PF16662.5 CDJ47344.1 - 1.1 9.4 5.9 0.79 9.8 0.1 3.0 3 0 0 3 3 3 0 FLYWCH-type zinc finger-containing protein 1 AMPK1_CBM PF16561.5 CDJ47345.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase TFIIA PF03153.13 CDJ47345.1 - 7.4 6.4 35.7 14 5.5 35.6 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BT1 PF03092.16 CDJ47346.1 - 1.5e-78 264.3 24.2 6.2e-55 186.4 12.0 2.1 2 0 0 2 2 2 2 BT1 family MFS_1 PF07690.16 CDJ47346.1 - 0.0018 17.3 9.1 0.0018 17.3 9.1 4.0 1 1 2 4 4 4 3 Major Facilitator Superfamily RIFIN PF02009.16 CDJ47348.1 - 1.2 9.0 9.9 0.32 10.8 7.0 1.4 1 1 0 1 1 1 0 Rifin RskA PF10099.9 CDJ47349.1 - 0.0065 16.8 8.7 0.0065 16.8 8.7 11.3 2 1 6 8 8 8 2 Anti-sigma-K factor rskA ALMT PF11744.8 CDJ47350.1 - 2.3 7.0 5.7 2.5 6.8 5.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Apt1 PF10351.9 CDJ47350.1 - 6.2 5.6 16.5 6.6 5.5 16.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3446 PF11928.8 CDJ47350.1 - 6.5 7.1 20.2 3 8.2 4.1 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain PhnG PF06754.12 CDJ47351.1 - 0.1 12.6 0.1 0.1 12.6 0.1 11.8 10 3 2 12 12 12 0 Phosphonate metabolism protein PhnG FA_desaturase PF00487.24 CDJ47352.1 - 0.028 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase RPA43_OB PF17875.1 CDJ47353.1 - 0.0018 18.9 2.3 0.0018 18.9 2.3 1.1 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I Presenilin PF01080.17 CDJ47353.1 - 0.0062 15.3 4.1 0.0065 15.3 4.1 1.1 1 0 0 1 1 1 1 Presenilin FAM176 PF14851.6 CDJ47353.1 - 0.01 15.5 3.2 0.01 15.5 3.2 1.1 1 0 0 1 1 1 0 FAM176 family DUF4666 PF15697.5 CDJ47353.1 - 0.017 15.8 1.7 0.018 15.7 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) EIIBC-GUT_N PF03612.14 CDJ47353.1 - 0.018 14.8 3.9 0.018 14.8 3.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SpoIIP PF07454.11 CDJ47353.1 - 0.041 13.3 4.9 0.04 13.4 4.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 CDJ47353.1 - 0.054 12.3 3.2 0.053 12.3 3.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 CDJ47353.1 - 0.063 13.5 4.8 0.068 13.4 4.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CobT PF06213.12 CDJ47353.1 - 0.073 12.4 11.3 0.07 12.5 11.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Connexin PF00029.19 CDJ47353.1 - 0.09 12.5 2.3 0.086 12.6 2.3 1.1 1 0 0 1 1 1 0 Connexin RNase_H2_suC PF08615.11 CDJ47353.1 - 0.09 13.0 3.0 0.084 13.0 3.0 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TRSP PF12500.8 CDJ47353.1 - 0.11 12.4 1.8 0.13 12.2 1.7 1.3 1 1 0 1 1 1 0 TRSP domain C terminus to PRTase_2 MAPEG PF01124.18 CDJ47353.1 - 0.15 12.0 0.6 0.18 11.7 0.6 1.2 1 0 0 1 1 1 0 MAPEG family OATP PF03137.20 CDJ47353.1 - 0.16 10.3 2.4 0.17 10.1 2.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AIF_C PF14721.6 CDJ47353.1 - 0.19 12.1 2.9 0.18 12.1 2.9 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CbtA PF09490.10 CDJ47353.1 - 0.23 11.2 1.0 0.26 11.0 1.0 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DDHD PF02862.17 CDJ47353.1 - 0.54 10.4 4.6 0.52 10.4 4.6 1.1 1 0 0 1 1 1 0 DDHD domain DUF4834 PF16118.5 CDJ47353.1 - 0.65 11.0 8.9 0.96 10.5 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CLN3 PF02487.17 CDJ47353.1 - 0.74 8.8 2.9 0.72 8.8 2.9 1.1 1 0 0 1 1 1 0 CLN3 protein FSAP_sig_propep PF03032.15 CDJ47353.1 - 0.91 9.6 0.1 0.91 9.6 0.1 3.0 2 1 0 2 2 1 0 Frog skin active peptide family signal and propeptide DUF2722 PF10846.8 CDJ47353.1 - 1.1 8.1 17.3 1.2 8.0 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4175 PF13779.6 CDJ47353.1 - 2.1 6.2 22.2 2.5 5.9 22.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.13 CDJ47353.1 - 2.1 8.3 18.2 2.3 8.1 18.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3464 PF11947.8 CDJ47353.1 - 2.7 7.7 7.7 3.7 7.3 7.7 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 G0-G1_switch_2 PF15103.6 CDJ47353.1 - 4.2 7.8 9.6 1.8 9.0 7.4 1.4 2 0 0 2 2 1 0 G0/G1 switch protein 2 TERB2 PF15101.6 CDJ47353.1 - 4.9 7.1 11.2 6.3 6.8 11.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 UPF0560 PF10577.9 CDJ47353.1 - 6.6 5.1 9.6 5.7 5.3 9.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pentapeptide_4 PF13599.6 CDJ47354.1 - 9.3 6.5 15.1 2.4 8.4 2.7 2.6 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) DUF2722 PF10846.8 CDJ47355.1 - 0.00016 20.8 2.8 0.00023 20.3 2.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Dfp1_Him1_M PF08630.10 CDJ47355.1 - 0.064 13.5 1.1 0.11 12.7 1.1 1.4 1 0 0 1 1 1 0 Dfp1/Him1, central region Spt20 PF12090.8 CDJ47355.1 - 1.9 8.1 20.8 3 7.4 20.8 1.2 1 0 0 1 1 1 0 Spt20 family Iso_dh PF00180.20 CDJ47357.1 - 1.1e-07 31.3 0.0 1.2e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Isocitrate/isopropylmalate dehydrogenase SR-25 PF10500.9 CDJ47357.1 - 5.7 6.5 48.6 59 3.2 48.6 2.2 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ47358.1 - 8.2e-05 22.3 80.4 0.0056 16.3 4.3 4.3 4 0 0 4 4 4 4 Spt20 family T4_tail_cap PF11091.8 CDJ47358.1 - 0.081 11.8 0.1 0.081 11.8 0.1 2.0 2 0 0 2 2 2 0 Tail-tube assembly protein EPL1 PF10513.9 CDJ47358.1 - 2.2 8.7 22.2 7 7.0 1.1 4.5 4 0 0 4 4 4 0 Enhancer of polycomb-like Mit_KHE1 PF10173.9 CDJ47358.1 - 4.7 7.2 20.4 0.3 11.2 0.1 4.0 4 0 0 4 4 4 0 Mitochondrial K+-H+ exchange-related DUF853 PF05872.12 CDJ47360.1 - 0.027 13.1 0.1 0.028 13.0 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Spt20 PF12090.8 CDJ47360.1 - 0.53 9.8 10.8 0.63 9.6 10.8 1.2 1 0 0 1 1 1 0 Spt20 family FHIPEP PF00771.20 CDJ47361.1 - 0.22 9.9 17.8 0.34 9.3 17.8 1.3 1 0 0 1 1 1 0 FHIPEP family CD20 PF04103.15 CDJ47361.1 - 0.34 11.0 1.6 0.41 10.7 0.8 1.6 1 1 0 1 1 1 0 CD20-like family SID-1_RNA_chan PF13965.6 CDJ47361.1 - 0.35 9.2 12.0 0.38 9.1 12.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 CDJ47361.1 - 0.92 8.2 32.6 1.2 7.9 32.6 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CDJ47361.1 - 1.2 7.3 20.7 1.4 7.1 20.7 1.2 1 0 0 1 1 1 0 CDC45-like protein BAF1_ABF1 PF04684.13 CDJ47361.1 - 2.6 7.0 28.0 3.3 6.7 28.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Serinc PF03348.15 CDJ47361.1 - 3.1 6.6 17.3 3.7 6.4 17.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Trp_oprn_chp PF09534.10 CDJ47361.1 - 4.2 7.1 22.8 11 5.8 22.7 1.6 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sin_N PF04801.13 CDJ47362.1 - 0.0023 17.2 9.5 0.0023 17.2 9.5 1.7 2 0 0 2 2 2 1 Sin-like protein conserved region RLL PF10036.9 CDJ47362.1 - 0.0097 15.8 5.6 0.0097 15.8 5.6 1.7 2 0 0 2 2 2 1 RNA transcription, translation and transport factor protein EIIBC-GUT_N PF03612.14 CDJ47362.1 - 0.012 15.4 3.8 0.024 14.4 3.8 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus EPL1 PF10513.9 CDJ47362.1 - 0.015 15.7 1.6 0.015 15.7 1.6 1.6 2 0 0 2 2 1 0 Enhancer of polycomb-like Sporozoite_P67 PF05642.11 CDJ47362.1 - 0.02 13.0 1.4 0.043 11.9 0.0 2.0 2 1 0 2 2 2 0 Sporozoite P67 surface antigen OATP PF03137.20 CDJ47362.1 - 0.022 13.1 0.6 0.036 12.4 0.6 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1980 PF09323.10 CDJ47362.1 - 0.025 14.5 1.9 1.1 9.1 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PEX11 PF05648.14 CDJ47362.1 - 0.052 13.0 1.0 0.096 12.1 1.0 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) V_ATPase_I PF01496.19 CDJ47362.1 - 0.058 11.3 1.6 0.09 10.7 1.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SpoIIP PF07454.11 CDJ47362.1 - 0.059 12.8 3.2 0.092 12.2 3.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF1943 PF09172.11 CDJ47362.1 - 0.15 11.3 3.1 0.24 10.6 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) SAE2 PF08573.10 CDJ47362.1 - 0.16 13.1 7.4 11 7.2 0.0 2.6 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus FAM176 PF14851.6 CDJ47362.1 - 0.32 10.7 2.8 0.63 9.7 2.8 1.4 1 0 0 1 1 1 0 FAM176 family ORC_WH_C PF18137.1 CDJ47362.1 - 0.66 10.1 7.7 2.3 8.3 7.7 1.9 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Connexin PF00029.19 CDJ47362.1 - 3.9 7.2 5.0 6.8 6.4 5.0 1.3 1 0 0 1 1 1 0 Connexin PigN PF04987.14 CDJ47362.1 - 3.9 6.2 4.8 7 5.4 4.8 1.3 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Neur_chan_memb PF02932.16 CDJ47362.1 - 5.5 7.0 5.5 1.9 8.5 1.6 2.0 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region FHIPEP PF00771.20 CDJ47362.1 - 6.5 5.1 9.8 0.61 8.5 4.8 1.6 2 0 0 2 2 2 0 FHIPEP family EphA2_TM PF14575.6 CDJ47362.1 - 6.7 7.7 6.1 13 6.7 4.5 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3464 PF11947.8 CDJ47362.1 - 7 6.4 8.7 15 5.3 8.7 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FAM60A PF15396.6 CDJ47362.1 - 7.1 6.6 8.4 9.3 6.2 3.6 2.3 2 1 0 2 2 2 0 Protein Family FAM60A eIF-3_zeta PF05091.12 CDJ47362.1 - 7.9 5.3 13.0 12 4.7 13.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SR-25 PF10500.9 CDJ47362.1 - 8.3 5.9 18.8 12 5.5 10.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF702 PF05142.12 CDJ47362.1 - 9.5 6.7 12.2 0.71 10.3 6.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF4762 PF15959.5 CDJ47363.1 - 0.0069 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4762) RVT_1 PF00078.27 CDJ47364.1 - 6.8e-14 51.9 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FRQ PF09421.10 CDJ47366.1 - 0.00044 18.4 5.0 0.00044 18.4 5.0 3.3 3 0 0 3 3 3 1 Frequency clock protein Pex14_N PF04695.13 CDJ47366.1 - 0.018 15.7 18.6 0.018 15.7 18.6 7.9 3 2 3 7 7 7 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF572 PF04502.13 CDJ47366.1 - 1.2 8.7 71.1 0.13 11.9 11.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF572) DUF2946 PF11162.8 CDJ47367.1 - 0.044 14.5 3.6 0.055 14.1 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) CCDC53 PF10152.9 CDJ47367.1 - 0.06 13.8 8.4 0.063 13.7 8.4 1.0 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex V_ATPase_I PF01496.19 CDJ47367.1 - 0.072 11.0 9.9 0.076 10.9 9.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ47367.1 - 0.091 12.5 4.6 0.09 12.5 4.6 1.0 1 0 0 1 1 1 0 Connexin CSG2 PF16965.5 CDJ47367.1 - 0.11 11.4 4.0 0.12 11.4 4.0 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator FAM176 PF14851.6 CDJ47367.1 - 0.14 11.8 2.5 0.17 11.6 2.5 1.1 1 0 0 1 1 1 0 FAM176 family Ctr PF04145.15 CDJ47367.1 - 0.19 12.3 6.1 0.19 12.3 6.1 1.0 1 0 0 1 1 1 0 Ctr copper transporter family ABC2_membrane_2 PF12679.7 CDJ47367.1 - 0.24 10.7 4.3 0.27 10.5 4.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein T2SSC PF11356.8 CDJ47367.1 - 0.26 11.2 8.8 0.27 11.1 8.8 1.0 1 0 0 1 1 1 0 Type II secretion system protein C Scs3p PF10261.9 CDJ47367.1 - 0.28 10.7 3.5 0.27 10.7 3.5 1.0 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM PIP5K PF01504.18 CDJ47367.1 - 0.3 10.3 6.5 0.32 10.2 6.5 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF2828 PF11443.8 CDJ47367.1 - 0.31 9.1 7.8 0.32 9.0 7.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CPSF100_C PF13299.6 CDJ47367.1 - 0.44 10.7 7.6 0.49 10.6 7.6 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoVR PF04293.13 CDJ47367.1 - 0.48 9.1 9.0 0.51 9.0 9.0 1.0 1 0 0 1 1 1 0 SpoVR like protein CLN3 PF02487.17 CDJ47367.1 - 0.49 9.4 6.4 0.47 9.4 6.4 1.0 1 0 0 1 1 1 0 CLN3 protein YABBY PF04690.13 CDJ47367.1 - 0.52 10.9 8.0 0.58 10.7 8.0 1.0 1 0 0 1 1 1 0 YABBY protein Baculo_PP31 PF05311.11 CDJ47367.1 - 0.62 9.5 10.8 0.63 9.5 10.8 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Mem_trans PF03547.18 CDJ47367.1 - 0.63 8.4 2.0 0.6 8.4 2.0 1.0 1 0 0 1 1 1 0 Membrane transport protein SpoIIP PF07454.11 CDJ47367.1 - 0.74 9.2 10.2 0.86 9.0 10.2 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CobT PF06213.12 CDJ47367.1 - 0.75 9.1 14.5 0.88 8.9 14.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Serinc PF03348.15 CDJ47367.1 - 0.99 8.3 3.4 0.98 8.3 3.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.6 CDJ47367.1 - 0.99 7.7 2.8 1 7.7 2.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 O-antigen_lig PF13425.6 CDJ47367.1 - 1.1 8.0 1.8 1.1 7.9 1.8 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Sec62 PF03839.16 CDJ47367.1 - 1.2 8.6 7.1 1.3 8.5 7.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 OATP PF03137.20 CDJ47367.1 - 1.3 7.2 4.6 1.2 7.3 4.6 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Neur_chan_memb PF02932.16 CDJ47367.1 - 1.8 8.6 7.9 2 8.4 7.9 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AIF_C PF14721.6 CDJ47367.1 - 2.4 8.5 7.2 2.9 8.3 7.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Endonuc_Holl PF10107.9 CDJ47367.1 - 2.6 7.8 9.6 2.7 7.8 9.6 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase FPN1 PF06963.12 CDJ47367.1 - 2.9 6.4 4.9 3.1 6.3 4.9 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Hydin_ADK PF17213.3 CDJ47367.1 - 3.1 8.0 10.4 3.8 7.7 10.4 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Band_3_cyto PF07565.13 CDJ47367.1 - 3.2 7.5 11.2 3.6 7.3 11.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ALMT PF11744.8 CDJ47367.1 - 3.2 6.5 6.7 3.5 6.3 6.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 CDJ47367.1 - 3.3 6.4 14.6 3.7 6.2 14.6 1.0 1 0 0 1 1 1 0 Presenilin FliP PF00813.20 CDJ47367.1 - 3.4 7.5 6.1 3.7 7.4 6.1 1.1 1 0 0 1 1 1 0 FliP family Pex14_N PF04695.13 CDJ47367.1 - 4 8.1 23.7 4.7 7.9 23.7 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_U57 PF05582.12 CDJ47367.1 - 4.1 6.6 8.8 4.3 6.5 8.8 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF1980 PF09323.10 CDJ47367.1 - 7 6.5 9.6 8.5 6.3 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RR_TM4-6 PF06459.12 CDJ47367.1 - 9.3 6.0 11.8 11 5.8 11.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RskA PF10099.9 CDJ47368.1 - 0.0034 17.7 8.7 0.0044 17.3 8.7 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ47368.1 - 0.088 12.4 7.5 0.096 12.3 7.5 1.1 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 CDJ47368.1 - 0.31 10.0 3.0 0.36 9.8 3.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ47368.1 - 0.48 10.4 9.9 0.56 10.1 9.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ47368.1 - 0.66 10.6 13.4 1 10.0 13.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Med3 PF11593.8 CDJ47368.1 - 1.4 8.1 11.7 1.8 7.6 11.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Activator_LAG-3 PF11498.8 CDJ47368.1 - 2.4 7.1 18.9 3.3 6.6 18.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pkinase_fungal PF17667.1 CDJ47369.1 - 3.1 6.5 5.4 6.3 5.5 5.4 1.4 1 0 0 1 1 1 0 Fungal protein kinase X PF00739.19 CDJ47370.1 - 0.0047 17.1 3.7 0.0047 17.1 3.7 7.3 7 2 2 10 10 10 1 Trans-activation protein X RskA PF10099.9 CDJ47370.1 - 0.0061 16.9 17.4 0.011 16.1 13.0 10.5 5 3 4 9 9 9 3 Anti-sigma-K factor rskA PCRF PF03462.18 CDJ47371.1 - 6e-12 45.8 10.1 2.3e-11 43.9 9.9 2.1 1 1 0 1 1 1 1 PCRF domain Methyltransf_23 PF13489.6 CDJ47371.1 - 0.17 11.7 1.5 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase domain Spt20 PF12090.8 CDJ47371.1 - 0.28 10.8 34.1 0.021 14.4 8.3 3.0 3 0 0 3 3 3 0 Spt20 family Neur_chan_memb PF02932.16 CDJ47371.1 - 0.58 10.2 9.4 0.19 11.8 3.8 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2298 PF10060.9 CDJ47372.1 - 0.23 10.1 2.6 0.24 10.1 2.6 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) DUF3568 PF12092.8 CDJ47372.1 - 0.45 10.6 5.2 0.5 10.5 4.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3568) CDK5_activator PF03261.15 CDJ47372.1 - 1.3 8.5 16.1 1.5 8.3 16.1 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SOBP PF15279.6 CDJ47372.1 - 1.4 9.4 19.5 1.6 9.3 19.5 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Vac7 PF12751.7 CDJ47372.1 - 1.5 8.2 13.5 1.5 8.1 13.5 1.0 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Nop53 PF07767.11 CDJ47372.1 - 3.1 7.1 31.2 3.7 6.8 31.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SprA-related PF12118.8 CDJ47372.1 - 5.6 6.0 42.2 6.9 5.7 42.2 1.0 1 0 0 1 1 1 0 SprA-related family PAT1 PF09770.9 CDJ47372.1 - 7 4.8 35.3 6.9 4.8 35.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ47372.1 - 7.3 4.7 17.3 8 4.6 17.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Cation_ATPase PF13246.6 CDJ47373.1 - 4.9e-05 23.3 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) RskA PF10099.9 CDJ47373.1 - 5.4 7.3 37.4 12 6.1 18.2 3.6 3 0 0 3 3 3 0 Anti-sigma-K factor rskA DTW PF03942.15 CDJ47374.1 - 9.8e-06 25.4 17.2 9.8e-06 25.4 17.2 3.2 1 1 0 2 2 2 1 DTW domain DUF4464 PF14713.6 CDJ47375.1 - 7.2e-13 48.6 10.4 1.2e-12 47.9 10.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4464) Maf1 PF09174.10 CDJ47375.1 - 0.0036 17.5 5.5 0.0048 17.1 5.5 1.2 1 0 0 1 1 1 1 Maf1 regulator Activator_LAG-3 PF11498.8 CDJ47375.1 - 0.007 15.4 24.8 0.0065 15.5 24.8 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 DUF2052 PF09747.9 CDJ47375.1 - 0.0076 16.4 12.0 0.01 16.0 12.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) TERB2 PF15101.6 CDJ47375.1 - 0.014 15.4 8.8 0.015 15.4 8.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CPSF100_C PF13299.6 CDJ47375.1 - 0.019 15.1 5.7 0.024 14.8 5.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Y2_Tnp PF04986.13 CDJ47375.1 - 0.032 14.3 3.7 0.045 13.8 3.7 1.3 1 0 0 1 1 1 0 Putative transposase Pex14_N PF04695.13 CDJ47375.1 - 0.036 14.7 10.3 0.043 14.5 10.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIP PF07454.11 CDJ47375.1 - 0.043 13.3 5.9 0.045 13.2 5.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AIF_C PF14721.6 CDJ47375.1 - 0.043 14.2 2.9 0.053 13.9 2.9 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TFIIA PF03153.13 CDJ47375.1 - 0.056 13.4 21.5 0.062 13.3 21.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ47375.1 - 0.089 12.9 5.2 0.089 12.9 5.2 1.1 1 0 0 1 1 1 0 DDHD domain Baculo_PP31 PF05311.11 CDJ47375.1 - 0.093 12.2 5.4 0.11 12.0 5.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Hydin_ADK PF17213.3 CDJ47375.1 - 0.096 13.0 4.6 0.11 12.8 4.6 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MCU PF04678.13 CDJ47375.1 - 0.098 12.7 5.0 0.11 12.5 5.0 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Serinc PF03348.15 CDJ47375.1 - 0.11 11.4 4.0 0.11 11.4 4.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) EIIBC-GUT_N PF03612.14 CDJ47375.1 - 0.12 12.1 3.4 0.13 12.0 3.4 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus eIF-3_zeta PF05091.12 CDJ47375.1 - 0.13 11.3 10.1 0.13 11.2 10.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Folate_carrier PF01770.18 CDJ47375.1 - 0.13 10.9 3.4 0.14 10.9 3.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier Presenilin PF01080.17 CDJ47375.1 - 0.14 10.9 8.4 0.14 10.9 8.4 1.0 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ47375.1 - 0.16 12.9 7.9 0.25 12.3 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ47375.1 - 0.16 11.6 4.0 0.22 11.2 4.0 1.3 1 0 0 1 1 1 0 FAM176 family Neur_chan_memb PF02932.16 CDJ47375.1 - 0.18 11.8 3.3 0.17 11.9 3.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM222A PF15258.6 CDJ47375.1 - 0.19 10.8 12.9 0.19 10.8 12.9 1.0 1 0 0 1 1 1 0 Protein family of FAM222A Hid1 PF12722.7 CDJ47375.1 - 0.26 9.4 6.4 0.26 9.4 6.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Insulin PF00049.18 CDJ47375.1 - 0.29 12.2 5.7 0.45 11.5 5.7 1.3 1 0 0 1 1 1 0 Insulin/IGF/Relaxin family Ureide_permease PF07168.11 CDJ47375.1 - 0.43 9.3 1.6 0.47 9.2 1.6 1.1 1 0 0 1 1 1 0 Ureide permease V_ATPase_I PF01496.19 CDJ47375.1 - 0.54 8.1 8.9 0.56 8.1 8.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ47375.1 - 0.69 9.6 5.8 0.75 9.5 5.8 1.1 1 0 0 1 1 1 0 Connexin YABBY PF04690.13 CDJ47375.1 - 0.74 10.4 5.3 0.96 10.0 5.3 1.2 1 0 0 1 1 1 0 YABBY protein FAM70 PF14967.6 CDJ47375.1 - 0.81 9.1 3.5 0.91 8.9 3.5 1.1 1 0 0 1 1 1 0 FAM70 protein EOS1 PF12326.8 CDJ47375.1 - 0.96 9.4 2.7 1.1 9.2 2.7 1.1 1 0 0 1 1 1 0 N-glycosylation protein G0-G1_switch_2 PF15103.6 CDJ47375.1 - 0.98 9.9 6.5 1.4 9.4 6.5 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 PepSY_TM PF03929.16 CDJ47375.1 - 1 8.9 4.4 1.2 8.7 4.4 1.1 1 0 0 1 1 1 0 PepSY-associated TM region NEMP PF10225.9 CDJ47375.1 - 1.1 8.9 5.8 1.4 8.6 5.8 1.1 1 0 0 1 1 1 0 NEMP family ALMT PF11744.8 CDJ47375.1 - 1.2 7.8 5.0 1.4 7.7 5.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PBP_sp32 PF07222.12 CDJ47375.1 - 1.3 8.4 11.8 1.5 8.2 11.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF4407 PF14362.6 CDJ47375.1 - 1.4 8.2 13.1 1.5 8.1 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.11 CDJ47375.1 - 1.5 7.2 13.0 1.8 7.0 13.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4175 PF13779.6 CDJ47375.1 - 1.9 6.3 24.1 2.2 6.1 24.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FPN1 PF06963.12 CDJ47375.1 - 2.5 6.6 5.5 2.9 6.3 5.5 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF775 PF05603.12 CDJ47375.1 - 2.8 7.4 11.0 6.6 6.2 11.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF775) AAA_23 PF13476.6 CDJ47375.1 - 3.1 8.3 14.3 3.6 8.0 14.3 1.1 1 0 0 1 1 1 0 AAA domain Ctr PF04145.15 CDJ47375.1 - 3.1 8.4 7.0 4.2 8.0 7.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Med15 PF09606.10 CDJ47375.1 - 4.6 5.8 24.1 5.2 5.6 24.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_UL32 PF06070.11 CDJ47375.1 - 4.6 4.8 13.3 5.5 4.6 13.3 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF4192 PF13830.6 CDJ47375.1 - 5.2 7.0 7.9 6.2 6.8 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF3408 PF11888.8 CDJ47375.1 - 8 6.6 15.7 3.4 7.8 12.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3408) CLN3 PF02487.17 CDJ47375.1 - 8.5 5.3 8.2 10 5.0 8.2 1.1 1 0 0 1 1 1 0 CLN3 protein DUF3573 PF12097.8 CDJ47375.1 - 9.5 4.9 7.6 9.4 4.9 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DCR PF14047.6 CDJ47378.1 - 0.0072 16.5 3.8 2.3 8.5 0.1 4.1 2 2 3 5 5 5 3 Dppa2/4 conserved region DUF2635 PF10948.8 CDJ47378.1 - 0.18 11.5 21.2 3.4 7.5 0.1 6.5 3 2 4 7 7 7 0 Protein of unknown function (DUF2635) Macoilin PF09726.9 CDJ47379.1 - 6.1 5.3 7.3 7.3 5.0 7.3 1.1 1 0 0 1 1 1 0 Macoilin family DDHD PF02862.17 CDJ47380.1 - 0.1 12.7 12.1 0.13 12.3 12.1 1.2 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 CDJ47380.1 - 0.77 9.7 46.7 1.1 9.2 46.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ47380.1 - 1.8 8.6 10.4 2.4 8.2 10.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MAT1 PF06391.13 CDJ47380.1 - 5.8 6.7 23.0 8 6.2 23.0 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TCP PF03634.13 CDJ47380.1 - 5.9 7.4 19.9 9.2 6.8 19.9 1.2 1 0 0 1 1 1 0 TCP family transcription factor Tho2 PF11262.8 CDJ47381.1 - 4.2e-22 78.7 0.2 4.9e-20 71.9 0.0 5.5 4 2 2 6 6 6 2 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 CDJ47381.1 - 3.1e-05 22.8 2.4 3.1e-05 22.8 2.4 6.6 6 2 1 8 8 8 1 THO complex subunit 2 N-terminus Thoc2 PF11732.8 CDJ47381.1 - 0.00075 19.5 0.0 0.0024 17.9 0.0 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit DUF2722 PF10846.8 CDJ47381.1 - 0.0016 17.5 0.8 0.0016 17.5 0.8 12.1 8 3 2 10 10 10 2 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ47381.1 - 0.0019 18.5 9.9 0.0019 18.5 9.9 17.0 8 4 2 11 11 11 3 Anti-sigma-K factor rskA DUF4667 PF15700.5 CDJ47381.1 - 0.01 15.9 0.0 0.01 15.9 0.0 14.6 5 4 4 11 11 11 0 Domain of unknown function (DUF4667) SUIM_assoc PF16619.5 CDJ47382.1 - 0.014 15.4 5.3 0.014 15.4 5.3 9.6 6 2 2 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ47382.1 - 1.1 8.9 109.0 0.053 13.1 19.4 4.9 5 0 0 5 5 5 0 Spt20 family RskA PF10099.9 CDJ47383.1 - 0.00017 21.9 11.4 0.00027 21.3 11.4 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA K_channel_TID PF07941.11 CDJ47383.1 - 0.00045 20.6 11.2 0.00045 20.6 11.2 2.9 2 1 0 2 2 1 1 Potassium channel Kv1.4 tandem inactivation domain HemX PF04375.14 CDJ47383.1 - 0.073 12.3 20.5 0.093 12.0 20.5 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Peptidase_C37 PF05416.12 CDJ47383.1 - 0.16 10.5 4.0 0.17 10.4 4.0 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Activator_LAG-3 PF11498.8 CDJ47383.1 - 0.25 10.3 28.7 0.25 10.3 28.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 R_equi_Vir PF05526.11 CDJ47383.1 - 0.61 9.9 6.8 0.76 9.6 6.8 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein TFIIA PF03153.13 CDJ47383.1 - 0.84 9.6 28.6 0.92 9.4 28.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ctr PF04145.15 CDJ47383.1 - 1 10.0 3.5 1.2 9.7 3.5 1.1 1 0 0 1 1 1 0 Ctr copper transporter family PBP_sp32 PF07222.12 CDJ47383.1 - 1.3 8.4 15.5 1.3 8.4 15.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PAT1 PF09770.9 CDJ47383.1 - 1.4 7.0 18.1 1.5 7.0 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BORG_CEP PF14957.6 CDJ47383.1 - 1.5 10.0 7.5 1.8 9.7 7.5 1.1 1 0 0 1 1 1 0 Cdc42 effector Suf PF05843.14 CDJ47383.1 - 1.6 8.6 13.5 1.7 8.5 13.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1980 PF09323.10 CDJ47383.1 - 2.3 8.1 7.4 2.8 7.8 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 CDJ47383.1 - 2.5 6.8 14.0 2.5 6.8 14.0 1.0 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 CDJ47383.1 - 2.6 8.1 15.0 3 7.8 15.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Serinc PF03348.15 CDJ47383.1 - 2.7 6.8 5.2 2.8 6.8 5.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pex14_N PF04695.13 CDJ47383.1 - 2.9 8.5 17.2 3.9 8.1 17.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.22 CDJ47383.1 - 3.2 6.9 6.5 3.4 6.8 6.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 CDJ47383.1 - 3.9 5.3 11.1 3.9 5.3 11.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF-3_zeta PF05091.12 CDJ47383.1 - 4.8 6.0 13.6 4.7 6.1 13.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 CDJ47383.1 - 5.4 6.7 8.2 6.1 6.5 8.2 1.1 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 CDJ47383.1 - 5.7 6.9 9.0 6.5 6.7 9.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 CDJ47383.1 - 7.8 6.0 31.1 9.6 5.7 31.1 1.1 1 0 0 1 1 1 0 Spt20 family PRR18 PF15671.5 CDJ47384.1 - 0.011 15.6 10.4 0.02 14.8 10.4 1.4 1 0 0 1 1 1 0 Proline-rich protein family 18 RAP1 PF07218.11 CDJ47384.1 - 0.23 9.7 1.4 0.29 9.3 1.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1387 PF07139.11 CDJ47384.1 - 4.4 7.0 18.2 6.5 6.4 18.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SRC-1 PF08832.10 CDJ47384.1 - 5.3 8.2 14.6 19 6.4 5.5 2.7 1 1 1 2 2 2 0 Steroid receptor coactivator DUF2057 PF09829.9 CDJ47385.1 - 0.34 11.0 5.8 0.3 11.2 5.8 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) RskA PF10099.9 CDJ47385.1 - 8 6.7 21.2 9 6.5 21.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TraT PF05818.12 CDJ47385.1 - 9.9 5.8 9.0 9.9 5.8 9.0 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein SPX PF03105.19 CDJ47387.1 - 1.7e-05 24.9 7.7 1.7e-05 24.9 7.7 9.1 5 2 1 6 6 6 2 SPX domain DUF2722 PF10846.8 CDJ47387.1 - 0.00021 20.4 3.6 0.00021 20.4 3.6 12.9 9 3 1 11 11 11 3 Protein of unknown function (DUF2722) TRAPPC10 PF12584.8 CDJ47387.1 - 0.011 15.5 0.0 0.13 12.0 0.0 3.1 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 Glyoxalase PF00903.25 CDJ47389.1 - 0.058 13.6 0.1 0.087 13.0 0.1 1.6 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SUIM_assoc PF16619.5 CDJ47389.1 - 0.61 10.2 6.7 5.1 7.2 0.3 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MASE1 PF05231.14 CDJ47390.1 - 0.015 14.5 0.9 0.016 14.3 0.9 1.0 1 0 0 1 1 1 0 MASE1 DUF3486 PF11985.8 CDJ47390.1 - 0.19 12.1 13.9 0.24 11.8 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Med3 PF11593.8 CDJ47390.1 - 0.23 10.6 11.9 0.27 10.4 11.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ47390.1 - 1.3 9.3 22.3 1.9 8.7 22.3 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2514 PF10721.9 CDJ47390.1 - 2.6 8.1 26.5 3 7.8 26.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) MSP1_C PF07462.11 CDJ47390.1 - 2.6 6.6 5.0 2.7 6.6 5.0 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus GT87 PF09594.10 CDJ47391.1 - 0.0014 18.4 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 87 Trypan_PARP PF05887.11 CDJ47391.1 - 0.0034 17.4 2.3 0.13 12.3 0.0 2.2 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) MecA PF05389.12 CDJ47391.1 - 0.0042 16.7 3.0 0.0042 16.7 3.0 2.2 2 0 0 2 2 2 1 Negative regulator of genetic competence (MecA) DUF3504 PF12012.8 CDJ47391.1 - 0.46 10.4 23.7 0.35 10.8 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) CbiD PF01888.17 CDJ47391.1 - 1.5 8.1 5.3 4.3 6.5 5.3 1.8 1 0 0 1 1 1 0 CbiD Cyt_bd_oxida_I PF01654.17 CDJ47391.1 - 2.1 6.8 3.3 2.9 6.4 3.3 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I Hydin_ADK PF17213.3 CDJ47391.1 - 2.8 8.2 31.7 2.1 8.6 14.3 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Peptidase_S49_N PF08496.10 CDJ47391.1 - 3.2 7.8 35.4 0.47 10.5 10.5 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3824 PF12868.7 CDJ47391.1 - 3.6 8.2 28.0 0.81 10.3 10.3 2.5 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) TRAP_alpha PF03896.16 CDJ47391.1 - 4.1 6.5 17.1 0.66 9.1 2.0 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Isy1 PF06246.12 CDJ47391.1 - 5.3 6.5 36.5 0.16 11.5 6.7 2.1 2 0 0 2 2 2 0 Isy1-like splicing family CDC45 PF02724.14 CDJ47391.1 - 7.2 4.8 31.7 2.5 6.3 8.8 2.1 2 0 0 2 2 2 0 CDC45-like protein FAM60A PF15396.6 CDJ47391.1 - 8.5 6.3 28.3 1.2 9.1 5.8 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Presenilin PF01080.17 CDJ47391.1 - 9.4 4.9 40.8 0.6 8.8 11.2 2.1 2 0 0 2 2 2 0 Presenilin DUF4667 PF15700.5 CDJ47392.1 - 0.0087 16.2 8.2 0.0088 16.2 8.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) SARAF PF06682.12 CDJ47392.1 - 0.4 10.3 11.8 0.45 10.1 11.8 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Apt1 PF10351.9 CDJ47392.1 - 0.58 9.0 5.6 0.55 9.0 5.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ47392.1 - 0.84 9.5 9.8 0.88 9.4 9.8 1.0 1 0 0 1 1 1 0 SPX domain BAF1_ABF1 PF04684.13 CDJ47392.1 - 7.5 5.5 6.9 9.2 5.2 6.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CCDC106 PF15794.5 CDJ47392.1 - 8.8 6.0 11.5 11 5.7 11.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Peroxin-3 PF04882.12 CDJ47392.1 - 9.2 5.1 8.2 9.3 5.1 8.2 1.0 1 0 0 1 1 1 0 Peroxin-3 Methyltransf_31 PF13847.6 CDJ47393.1 - 4.6e-06 26.5 0.0 4.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ47393.1 - 4.9e-05 23.9 0.0 6.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ47393.1 - 0.00018 22.2 0.0 0.00028 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ47393.1 - 0.0052 16.6 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ47393.1 - 0.038 13.3 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CDJ47393.1 - 0.046 14.4 0.0 0.082 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AF-4 PF05110.13 CDJ47394.1 - 2.7 6.0 55.7 3.1 5.8 55.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Imm5 PF14423.6 CDJ47396.1 - 0.25 11.5 7.5 0.21 11.8 1.8 2.3 2 0 0 2 2 2 0 Immunity protein Imm5 RAP1 PF07218.11 CDJ47396.1 - 3.1 6.0 11.6 4.6 5.4 11.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CDJ47396.1 - 9.3 5.8 28.1 0.9 9.1 19.6 2.3 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ47397.1 - 0.012 16.0 10.0 0.012 16.0 10.0 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ47397.1 - 0.2 10.4 16.7 0.24 10.1 16.7 1.0 1 0 0 1 1 1 0 Presenilin VIR_N PF15912.5 CDJ47397.1 - 0.4 10.3 7.4 0.46 10.0 7.4 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal Tim54 PF11711.8 CDJ47397.1 - 0.46 9.2 10.1 0.61 8.8 10.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Trp_oprn_chp PF09534.10 CDJ47397.1 - 0.54 10.0 8.1 0.082 12.7 1.2 1.9 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gti1_Pac2 PF09729.9 CDJ47397.1 - 0.58 10.2 10.4 0.68 10.0 10.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family RR_TM4-6 PF06459.12 CDJ47397.1 - 0.65 9.8 13.2 0.88 9.3 13.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2828 PF11443.8 CDJ47397.1 - 0.79 7.7 14.8 0.94 7.5 14.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF778 PF05608.12 CDJ47397.1 - 0.86 9.9 10.8 1 9.7 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Het-C PF07217.11 CDJ47397.1 - 1.3 7.4 10.9 1.5 7.2 10.9 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C IHABP4_N PF16174.5 CDJ47397.1 - 1.4 9.5 23.5 1.9 9.1 23.5 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Pal1 PF08316.11 CDJ47397.1 - 1.5 9.6 5.7 2.3 9.0 5.7 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF3292 PF11696.8 CDJ47397.1 - 2.1 6.6 11.3 2.4 6.4 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Hid1 PF12722.7 CDJ47397.1 - 2.3 6.2 14.8 2.5 6.1 14.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein O-antigen_lig PF13425.6 CDJ47397.1 - 2.4 6.9 5.4 2.7 6.7 5.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Coilin_N PF15862.5 CDJ47397.1 - 3 7.7 23.2 0.67 9.7 6.1 2.1 2 0 0 2 2 2 0 Coilin N-terminus CLN3 PF02487.17 CDJ47397.1 - 3.3 6.7 11.6 3.9 6.4 11.6 1.1 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 CDJ47397.1 - 4.6 6.0 12.9 5.2 5.8 12.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CD20 PF04103.15 CDJ47397.1 - 4.8 7.3 11.0 0.51 10.4 0.1 2.0 1 1 1 2 2 2 0 CD20-like family DcuC PF03606.15 CDJ47397.1 - 5.3 5.4 6.7 4.9 5.5 0.2 2.0 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier CNDH2_N PF06278.11 CDJ47397.1 - 5.3 7.3 18.2 6.5 7.0 4.5 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal LptF_LptG PF03739.14 CDJ47397.1 - 6 5.6 7.3 8.1 5.2 7.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG RNA_pol_Rbc25 PF08292.12 CDJ47397.1 - 6.5 7.0 13.2 6.9 6.9 1.8 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Ten_N PF06484.12 CDJ47397.1 - 6.5 6.5 11.3 7.9 6.3 11.3 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region Orf78 PF06024.12 CDJ47397.1 - 6.8 7.1 13.8 6.7 7.1 2.5 2.1 2 0 0 2 2 2 0 Orf78 (ac78) DUF4175 PF13779.6 CDJ47397.1 - 7.1 4.4 42.7 8.8 4.1 42.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) V_ATPase_I PF01496.19 CDJ47397.1 - 8.3 4.2 15.9 9.8 3.9 15.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 CDJ47397.1 - 8.4 6.4 14.4 10 6.1 14.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sox_N PF12444.8 CDJ47397.1 - 9 7.5 9.7 2.9 9.1 1.4 2.1 2 0 0 2 2 2 0 Sox developmental protein N terminal Ndc1_Nup PF09531.10 CDJ47397.1 - 9.6 4.8 15.7 12 4.4 15.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4834 PF16118.5 CDJ47398.1 - 0.0024 18.8 3.3 0.0024 18.8 3.3 6.3 4 2 2 6 6 6 1 Domain of unknown function (DUF4834) O-antigen_lig PF13425.6 CDJ47398.1 - 1 8.1 10.7 0.12 11.2 6.0 1.7 2 0 0 2 2 2 0 O-antigen ligase like membrane protein SID-1_RNA_chan PF13965.6 CDJ47398.1 - 2.2 6.6 13.5 0.1 11.0 6.0 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Ank_5 PF13857.6 CDJ47399.1 - 1.5e-10 41.1 1.8 5.9e-06 26.5 1.4 4.0 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ47399.1 - 6.4e-10 39.4 1.7 2.2e-07 31.3 0.3 3.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ47399.1 - 5.9e-09 36.4 1.9 5.9e-09 36.4 1.9 3.6 2 2 2 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ47399.1 - 2.6e-07 30.4 1.8 0.015 15.7 0.1 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 CDJ47399.1 - 1.4e-06 28.5 7.5 0.052 14.0 0.0 4.5 3 2 0 3 3 3 2 Ankyrin repeat RskA PF10099.9 CDJ47400.1 - 7.4e-06 26.4 11.8 7.4e-06 26.4 11.8 5.2 1 1 3 4 4 4 1 Anti-sigma-K factor rskA DUF1985 PF09331.11 CDJ47400.1 - 0.72 9.8 5.5 1.3 9.1 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) Pkinase PF00069.25 CDJ47402.1 - 1.8e-16 60.3 0.0 2.2e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ47402.1 - 1.9e-05 24.1 0.0 0.00011 21.6 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ47402.1 - 0.00025 20.5 0.0 0.0013 18.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.25 CDJ47403.1 - 3.8e-16 59.3 0.0 5.8e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 CDJ47403.1 - 2.8e-05 23.6 0.0 0.0047 16.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.17 CDJ47403.1 - 4.3e-05 22.9 0.0 9.6e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Bclt PF15318.6 CDJ47404.1 - 0.026 14.4 0.3 0.043 13.7 0.3 1.3 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis Ysc84 PF04366.12 CDJ47404.1 - 0.058 13.2 0.2 0.09 12.5 0.2 1.3 1 0 0 1 1 1 0 Las17-binding protein actin regulator SR-25 PF10500.9 CDJ47404.1 - 0.59 9.7 21.9 1.1 8.8 21.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ47405.1 - 0.00064 18.8 6.9 0.00064 18.8 6.9 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ47405.1 - 0.0016 18.1 12.7 0.0016 18.1 12.7 2.4 3 1 0 3 3 3 1 Spt20 family eIF-3_zeta PF05091.12 CDJ47405.1 - 0.089 11.8 2.6 0.12 11.3 2.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GpcrRhopsn4 PF10192.9 CDJ47405.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain SR-25 PF10500.9 CDJ47405.1 - 1.2 8.7 50.1 0.36 10.4 9.7 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ47405.1 - 2.5 6.8 12.4 0.21 10.3 6.2 2.1 2 0 0 2 2 2 0 Presenilin DUF5427 PF10310.9 CDJ47405.1 - 5.4 5.9 14.6 0.22 10.4 7.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5427) CIAPIN1 PF05093.13 CDJ47406.1 - 2.4e-20 72.9 16.0 9.5e-18 64.6 16.0 2.5 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis ATP-sulfurylase PF01747.17 CDJ47407.1 - 1.2e-85 286.3 0.1 1.6e-85 285.9 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 CDJ47407.1 - 8.8e-57 191.4 0.0 1.6e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 CDJ47407.1 - 1.2e-10 41.2 0.0 2.2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 CDJ47407.1 - 8.4e-07 29.2 0.0 2.7e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CDJ47407.1 - 7.7e-05 22.3 0.0 0.00015 21.3 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 CDJ47407.1 - 0.00043 20.6 0.4 0.0012 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ47407.1 - 0.0087 16.5 0.0 0.034 14.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 CDJ47407.1 - 0.01 16.4 0.0 0.027 15.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ47407.1 - 0.02 14.2 0.0 0.2 10.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 CDJ47407.1 - 0.11 12.6 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CDJ47407.1 - 0.16 11.7 0.0 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain MeaB PF03308.16 CDJ47407.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ACDC PF14733.6 CDJ47408.1 - 1.9e-23 82.6 0.2 5.4e-23 81.1 0.2 1.8 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ47408.1 - 4.9e-06 26.7 4.9 4.9e-06 26.7 4.9 2.8 4 0 0 4 4 4 1 AP2 domain Lin-8 PF03353.15 CDJ47408.1 - 4.2 6.8 10.0 0.34 10.4 4.8 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CDJ47408.1 - 5.4 6.5 17.2 0.42 10.2 11.9 1.8 2 0 0 2 2 2 0 Spt20 family MAP65_ASE1 PF03999.12 CDJ47408.1 - 6.3 5.4 14.9 0.11 11.1 7.1 1.9 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Laminin_G_3 PF13385.6 CDJ47409.1 - 7.8e-07 29.4 0.0 1.6e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Spt20 PF12090.8 CDJ47410.1 - 0.0061 16.2 14.3 0.0061 16.2 14.3 4.2 3 1 1 4 4 4 2 Spt20 family Spore_YhcN_YlaJ PF09580.10 CDJ47410.1 - 0.007 16.5 11.8 0.13 12.3 0.4 3.2 3 0 0 3 3 3 2 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF4770 PF15994.5 CDJ47410.1 - 0.82 9.9 28.9 0.32 11.2 3.5 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4770) SpoIIP PF07454.11 CDJ47410.1 - 8.9 5.7 19.0 0.86 9.0 0.4 3.5 4 0 0 4 4 4 0 Stage II sporulation protein P (SpoIIP) RskA PF10099.9 CDJ47411.1 - 1.4e-06 28.8 3.3 1.4e-06 28.8 3.3 5.0 3 3 1 4 4 4 1 Anti-sigma-K factor rskA CDK5_activator PF03261.15 CDJ47413.1 - 8.5 5.8 41.1 0.086 12.4 9.4 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein RskA PF10099.9 CDJ47414.1 - 3.2e-05 24.3 7.1 3.2e-05 24.3 7.1 3.3 1 1 2 3 3 3 2 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ47414.1 - 1.7 8.2 87.6 0.058 13.0 5.5 4.1 1 1 3 4 4 4 0 Nuclear RNA-splicing-associated protein ThiF PF00899.21 CDJ47415.1 - 9.6e-34 116.8 2.4 4.5e-21 75.3 0.5 2.6 2 1 0 2 2 2 2 ThiF family Macoilin PF09726.9 CDJ47415.1 - 0.0002 20.1 23.2 0.0002 20.1 23.2 3.0 3 0 0 3 3 3 1 Macoilin family UBA_e1_thiolCys PF10585.9 CDJ47415.1 - 0.056 13.4 0.0 0.056 13.4 0.0 3.7 3 1 2 5 5 5 0 Ubiquitin-activating enzyme active site Baculo_PP31 PF05311.11 CDJ47415.1 - 2.1 7.8 11.5 0.033 13.7 3.9 1.8 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) RskA PF10099.9 CDJ47416.1 - 5e-10 40.0 6.4 0.00023 21.5 0.1 20.1 5 3 8 13 13 13 4 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ47416.1 - 0.00071 19.2 12.0 0.00071 19.2 12.0 12.9 10 4 1 13 13 13 3 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ47416.1 - 0.0024 17.5 7.5 0.0024 17.5 7.5 10.5 9 2 1 10 10 10 5 Spt20 family Ras PF00071.22 CDJ47417.1 - 2e-30 105.5 0.1 2.3e-30 105.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ47417.1 - 3.4e-25 88.6 0.1 4e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ47417.1 - 1.4e-08 34.4 0.0 1.6e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ47417.1 - 5.4e-05 22.7 0.0 6.3e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ47417.1 - 0.00022 21.3 0.0 0.00025 21.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDJ47417.1 - 0.0015 18.0 0.0 0.0016 17.9 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CDJ47417.1 - 0.0024 18.3 0.0 0.0024 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ47417.1 - 0.0041 17.1 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CDJ47417.1 - 0.0065 16.7 0.0 0.0074 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ47417.1 - 0.0067 16.1 0.1 0.022 14.5 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 CDJ47417.1 - 0.0074 15.5 0.0 0.0096 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TniB PF05621.11 CDJ47417.1 - 0.01 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 CDJ47417.1 - 0.014 15.0 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 CDJ47417.1 - 0.021 14.1 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 CDJ47417.1 - 0.028 14.1 0.0 0.032 14.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CDJ47417.1 - 0.044 13.8 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CDJ47417.1 - 0.05 14.1 0.0 0.054 14.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter MCM PF00493.23 CDJ47417.1 - 0.12 11.5 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Spt20 PF12090.8 CDJ47418.1 - 2.2 7.8 28.2 0.13 11.9 8.4 2.4 3 0 0 3 3 3 0 Spt20 family Ank_2 PF12796.7 CDJ47419.1 - 0.00044 20.8 0.1 0.0014 19.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Spt20 PF12090.8 CDJ47419.1 - 0.0015 18.2 23.7 0.0015 18.2 23.7 3.2 3 0 0 3 3 3 1 Spt20 family Ank_3 PF13606.6 CDJ47419.1 - 0.0045 17.4 0.1 0.012 16.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 CDJ47419.1 - 0.0075 16.6 0.1 0.02 15.2 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) SUIM_assoc PF16619.5 CDJ47419.1 - 0.026 14.6 2.4 0.026 14.6 2.4 4.7 4 1 0 4 4 2 0 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 CDJ47419.1 - 0.11 12.9 15.8 0.84 10.0 9.6 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like EphA2_TM PF14575.6 CDJ47419.1 - 0.11 13.4 3.9 1.1 10.2 1.2 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NTP_transf_4 PF13562.6 CDJ47419.1 - 1.2 9.4 6.0 5 7.3 4.0 2.4 2 0 0 2 2 2 0 Sugar nucleotidyl transferase RuvC_III PF18541.1 CDJ47419.1 - 1.5 8.7 10.5 1.5 8.7 7.5 2.1 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 MecA PF05389.12 CDJ47419.1 - 1.5 8.4 13.2 0.97 9.0 7.9 2.7 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) TFIIA PF03153.13 CDJ47419.1 - 5.3 6.9 69.6 1.8 8.4 42.8 2.3 1 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 CDJ47419.1 - 6.1 7.1 34.8 3.9 7.7 22.6 3.0 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein MPM1 PF17234.2 CDJ47419.1 - 8.5 6.6 21.5 0.11 12.7 11.6 2.5 3 0 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 Sec62 PF03839.16 CDJ47419.1 - 9.6 5.6 10.5 3.2 7.2 7.1 1.9 2 0 0 2 2 2 0 Translocation protein Sec62 Ter PF05472.11 CDJ47420.1 - 0.026 13.6 0.1 0.036 13.1 0.1 1.2 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) Nnf1 PF03980.14 CDJ47420.1 - 0.076 13.4 7.7 2.5 8.5 0.2 2.6 3 0 0 3 3 3 0 Nnf1 DUF755 PF05501.11 CDJ47420.1 - 0.2 11.9 17.5 0.28 11.5 11.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) IMUP PF15761.5 CDJ47420.1 - 0.44 11.2 12.9 0.25 12.0 7.8 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein Secretin_N_2 PF07655.13 CDJ47420.1 - 2.9 8.5 12.1 0.64 10.6 4.6 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain CCSAP PF15748.5 CDJ47420.1 - 4.1 7.5 15.9 4.8 7.3 15.0 1.4 1 1 0 1 1 1 0 Centriole, cilia and spindle-associated PBP_sp32 PF07222.12 CDJ47420.1 - 4.6 6.6 9.6 6.2 6.2 9.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3843 PF12954.7 CDJ47423.1 - 0.14 11.1 1.5 0.18 10.8 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) Conotoxin PF02950.17 CDJ47423.1 - 6.1 7.9 6.8 11 7.1 0.5 2.7 2 0 0 2 2 2 0 Conotoxin DEAD PF00270.29 CDJ47424.1 - 5.8e-14 52.2 0.6 2.5e-12 46.9 0.8 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase SUIM_assoc PF16619.5 CDJ47424.1 - 0.012 15.6 7.8 0.012 15.6 7.8 6.0 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SAGA-Tad1 PF12767.7 CDJ47424.1 - 0.045 13.5 15.7 0.71 9.6 12.2 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit MMU163 PF17119.5 CDJ47424.1 - 0.66 9.1 7.0 2.3 7.3 2.9 2.4 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis DUF4446 PF14584.6 CDJ47424.1 - 1.2 9.2 6.4 1.6 8.7 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Sin_N PF04801.13 CDJ47424.1 - 2.5 7.2 32.7 2.8 7.0 23.5 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region SPX PF03105.19 CDJ47424.1 - 4.8 7.0 18.9 1.5e+02 2.1 18.9 2.4 1 1 0 1 1 1 0 SPX domain FAM60A PF15396.6 CDJ47424.1 - 7.5 6.5 11.5 8.5 6.3 7.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A PAT1 PF09770.9 CDJ47424.1 - 9.3 4.4 44.9 4.9 5.3 35.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 CDJ47426.1 - 0.18 11.7 16.4 0.24 11.3 16.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_LMP1 PF05297.11 CDJ47426.1 - 0.57 9.3 2.6 0.66 9.1 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2722 PF10846.8 CDJ47427.1 - 0.00059 18.9 7.5 0.00059 18.9 7.5 4.2 4 0 0 4 4 4 3 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ47427.1 - 0.0034 17.8 2.8 0.0034 17.8 2.8 3.9 3 1 0 3 3 3 1 Enhancer of polycomb-like Spt20 PF12090.8 CDJ47427.1 - 0.0052 16.4 17.7 0.0052 16.4 17.7 4.1 2 1 1 4 4 4 1 Spt20 family UbiD PF01977.16 CDJ47427.1 - 0.0054 15.6 0.7 0.02 13.8 0.7 1.9 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase PCSK9_C1 PF18459.1 CDJ47428.1 - 0.24 11.5 5.7 0.77 9.9 5.7 1.8 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain gag-asp_proteas PF13975.6 CDJ47429.1 - 0.00011 22.7 0.0 0.00035 21.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ47429.1 - 0.00011 22.7 0.0 0.00027 21.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDJ47429.1 - 0.013 15.2 0.0 0.032 14.0 0.0 1.6 2 0 0 2 2 2 0 Retroviral aspartyl protease Methyltr_RsmB-F PF01189.17 CDJ47430.1 - 1.3e-22 80.4 0.0 1.5e-08 34.6 0.0 5.2 2 1 0 3 3 3 3 16S rRNA methyltransferase RsmB/F Serendipity_A PF05482.12 CDJ47432.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) Popeye PF04831.13 CDJ47433.1 - 1.4e-11 44.7 0.0 2.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 CDJ47433.1 - 0.0004 20.4 0.3 0.052 13.6 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain APG17 PF04108.12 CDJ47434.1 - 0.019 14.1 1.5 0.037 13.2 1.5 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 Fib_alpha PF08702.10 CDJ47434.1 - 0.025 14.7 0.7 0.063 13.5 0.7 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CRAL_TRIO PF00650.20 CDJ47435.1 - 5.1e-20 71.8 0.0 8e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain TPR_21 PF09976.9 CDJ47436.1 - 0.095 12.4 0.1 0.62 9.7 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain OB_NTP_bind PF07717.16 CDJ47437.1 - 3.9e-11 43.1 0.0 1.4e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CDJ47437.1 - 7.3e-11 42.3 0.5 6.6e-10 39.2 0.1 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) SR-25 PF10500.9 CDJ47437.1 - 0.0017 18.0 8.6 0.0056 16.3 8.6 1.9 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4698 PF15769.5 CDJ47437.1 - 4.6 6.2 6.1 0.6 9.1 2.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) Tim17 PF02466.19 CDJ47438.1 - 2.3e-22 79.5 4.4 3.2e-22 79.0 4.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_L21p PF00829.21 CDJ47439.1 - 2.3e-05 24.6 0.3 5.6e-05 23.3 0.3 1.7 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein CIAPIN1 PF05093.13 CDJ47439.1 - 0.28 11.7 2.5 0.51 10.9 2.5 1.4 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Presenilin PF01080.17 CDJ47439.1 - 0.61 8.8 1.7 0.78 8.4 1.7 1.1 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ47440.1 - 0.0023 17.6 23.3 1.4 8.4 5.4 3.5 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ47440.1 - 0.0055 16.3 8.6 0.0055 16.3 8.6 4.9 4 1 0 4 4 4 2 Spt20 family eIF-3_zeta PF05091.12 CDJ47440.1 - 3.1 6.7 30.6 1.8 7.4 13.2 3.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1980 PF09323.10 CDJ47440.1 - 9.6 6.1 19.4 2.4 8.0 6.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) FAM60A PF15396.6 CDJ47441.1 - 1.1 9.2 9.1 4.1 7.3 1.5 2.2 2 0 0 2 2 2 0 Protein Family FAM60A SWI-SNF_Ssr4 PF08549.10 CDJ47441.1 - 1.5 7.4 24.7 1.9 7.0 24.7 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SOG2 PF10428.9 CDJ47441.1 - 1.7 7.7 30.6 2.3 7.3 30.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SLC12 PF03522.15 CDJ47442.1 - 2.9 6.8 38.2 0.59 9.1 11.8 2.1 2 0 0 2 2 2 0 Solute carrier family 12 DUF908 PF06012.12 CDJ47443.1 - 0.098 12.1 12.6 0.12 11.8 12.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) BAF1_ABF1 PF04684.13 CDJ47443.1 - 0.22 10.6 13.3 0.26 10.3 13.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor IER PF05760.12 CDJ47443.1 - 0.65 10.3 21.0 0.8 10.0 21.0 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) SARAF PF06682.12 CDJ47443.1 - 0.75 9.4 13.3 0.93 9.1 13.3 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis LptF_LptG PF03739.14 CDJ47443.1 - 0.91 8.3 6.6 1.1 8.1 6.6 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG 5_nucleotid PF05761.14 CDJ47443.1 - 1.6 7.5 12.5 1.8 7.4 12.5 1.1 1 0 0 1 1 1 0 5' nucleotidase family MAP7 PF05672.11 CDJ47443.1 - 1.8 8.2 31.7 2.6 7.7 31.7 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Presenilin PF01080.17 CDJ47443.1 - 2 7.1 18.4 2 7.1 18.4 1.2 1 0 0 1 1 1 0 Presenilin DDRGK PF09756.9 CDJ47443.1 - 2.3 7.8 17.7 3.5 7.2 17.7 1.5 1 0 0 1 1 1 0 DDRGK domain Lin-8 PF03353.15 CDJ47443.1 - 3.2 7.2 23.0 3.8 7.0 23.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Peptidase_S64 PF08192.11 CDJ47443.1 - 3.6 6.0 16.0 4.3 5.7 16.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 eIF-3_zeta PF05091.12 CDJ47443.1 - 3.9 6.3 20.6 5.4 5.9 20.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.10 CDJ47443.1 - 4.3 5.9 25.4 5.4 5.6 25.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Exonuc_VII_L PF02601.15 CDJ47443.1 - 4.5 6.7 19.8 6 6.3 19.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SLC12 PF03522.15 CDJ47443.1 - 5.4 5.9 16.9 6.1 5.8 16.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PIP5K PF01504.18 CDJ47443.1 - 5.4 6.2 9.6 6.6 5.9 9.6 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Membralin PF09746.9 CDJ47443.1 - 6.8 5.6 8.1 7.5 5.5 8.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein ALMT PF11744.8 CDJ47443.1 - 6.9 5.4 13.6 8.7 5.0 13.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 CDJ47443.1 - 7.6 5.7 8.3 8.1 5.5 8.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MDM10 PF12519.8 CDJ47443.1 - 9 5.0 16.3 11 4.8 16.3 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CLN3 PF02487.17 CDJ47443.1 - 9.7 5.1 11.1 11 4.9 11.1 1.2 1 0 0 1 1 1 0 CLN3 protein Hid1 PF12722.7 CDJ47444.1 - 8.2 4.4 10.3 8.4 4.4 10.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 CDJ47446.1 - 5.9 5.8 17.0 6.3 5.7 17.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF3712 PF12505.8 CDJ47447.1 - 2.2e-15 57.0 0.0 6.1e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Med3 PF11593.8 CDJ47447.1 - 0.00034 19.9 14.5 0.00034 19.9 14.5 2.2 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal Leader_Trp PF08255.11 CDJ47447.1 - 0.074 13.0 1.0 0.26 11.4 1.0 2.0 1 0 0 1 1 1 0 Trp-operon Leader Peptide Piezo_RRas_bdg PF12166.8 CDJ47447.1 - 0.1 11.8 6.2 0.14 11.4 6.2 1.2 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain LEA_2 PF03168.13 CDJ47447.1 - 0.15 12.6 1.8 0.16 12.5 0.0 1.9 2 0 0 2 2 1 0 Late embryogenesis abundant protein LAP1C PF05609.12 CDJ47447.1 - 0.17 11.0 18.5 0.28 10.2 18.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GET2 PF08690.10 CDJ47447.1 - 0.17 11.5 14.7 0.24 11.0 14.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 BAF1_ABF1 PF04684.13 CDJ47447.1 - 0.66 9.0 10.8 0.36 9.8 7.3 1.9 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Hamartin PF04388.12 CDJ47447.1 - 0.76 8.4 12.1 1.4 7.5 12.1 1.3 1 0 0 1 1 1 0 Hamartin protein Connexin PF00029.19 CDJ47447.1 - 1.4 8.6 5.7 4.4 7.0 2.6 2.1 2 0 0 2 2 2 0 Connexin XRN_M PF17846.1 CDJ47447.1 - 2.3 7.1 9.5 3.5 6.5 9.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain RAP1 PF07218.11 CDJ47447.1 - 3.2 5.9 10.2 4.4 5.5 10.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4407 PF14362.6 CDJ47447.1 - 4.8 6.5 17.5 1.2 8.4 10.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Suf PF05843.14 CDJ47447.1 - 5.1 7.0 20.7 4.8 7.1 13.7 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Herpes_pp85 PF04637.12 CDJ47447.1 - 5.1 5.4 6.3 7.2 4.9 6.3 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PAT1 PF09770.9 CDJ47447.1 - 8.7 4.5 23.9 11 4.1 23.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PH_4 PF15404.6 CDJ47447.1 - 9.6 6.0 9.3 3.8 7.3 3.6 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain End3 PF12761.7 CDJ47448.1 - 0.016 15.3 5.8 0.03 14.5 5.8 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF2937 PF11157.8 CDJ47448.1 - 0.021 14.5 1.8 0.021 14.5 1.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) PfUIS3 PF11567.8 CDJ47448.1 - 0.17 12.3 0.8 0.26 11.6 0.8 1.2 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein LCD1 PF09798.9 CDJ47448.1 - 0.19 10.2 3.1 0.24 9.9 3.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein COG6 PF06419.11 CDJ47448.1 - 0.5 8.5 10.9 0.69 8.1 10.9 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 COMM_domain PF07258.14 CDJ47448.1 - 0.72 10.0 8.3 0.089 12.9 3.8 1.8 2 0 0 2 2 2 0 COMM domain MMR1 PF08505.10 CDJ47448.1 - 5.2 7.3 6.9 23 5.1 6.9 1.9 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Amnionless PF14828.6 CDJ47448.1 - 7.4 5.3 8.2 14 4.3 8.2 1.5 1 1 0 1 1 1 0 Amnionless RskA PF10099.9 CDJ47449.1 - 1e-05 25.9 2.7 1e-05 25.9 2.7 5.5 1 1 3 5 5 5 1 Anti-sigma-K factor rskA Macoilin PF09726.9 CDJ47449.1 - 0.00022 19.9 23.7 0.00038 19.2 23.7 1.3 1 0 0 1 1 1 1 Macoilin family Cas_Cmr3 PF09700.10 CDJ47449.1 - 0.0079 15.7 1.0 0.017 14.6 1.0 1.5 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cmr3) Spt20 PF12090.8 CDJ47449.1 - 0.0081 15.8 11.0 0.0081 15.8 11.0 2.2 2 0 0 2 2 2 1 Spt20 family NCA2 PF08637.10 CDJ47449.1 - 0.039 13.1 1.5 0.068 12.3 1.5 1.3 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 SOBP PF15279.6 CDJ47449.1 - 0.063 13.9 13.8 0.091 13.4 13.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Miga PF10265.9 CDJ47449.1 - 0.17 10.8 18.4 0.26 10.2 18.4 1.3 1 0 0 1 1 1 0 Mitoguardin Utp14 PF04615.13 CDJ47449.1 - 2.6 6.5 16.9 3.8 6.0 16.9 1.4 1 0 0 1 1 1 0 Utp14 protein DFRP_C PF16543.5 CDJ47450.1 - 1.8e-16 60.4 0.9 1.8e-16 60.4 0.9 2.8 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 RskA PF10099.9 CDJ47450.1 - 0.0065 16.8 24.1 0.13 12.6 24.0 2.5 1 1 0 1 1 1 1 Anti-sigma-K factor rskA 5_nucleotid PF05761.14 CDJ47450.1 - 0.047 12.6 9.1 0.071 12.0 9.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family Exonuc_VII_L PF02601.15 CDJ47450.1 - 0.22 11.1 21.2 0.31 10.6 21.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 CDJ47450.1 - 0.49 9.3 10.5 0.55 9.1 10.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RIFIN PF02009.16 CDJ47450.1 - 0.56 10.0 11.9 0.78 9.6 11.9 1.3 1 0 0 1 1 1 0 Rifin Spt5_N PF11942.8 CDJ47450.1 - 0.75 10.8 16.7 2.2 9.3 9.6 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PRKCSH-like PF12999.7 CDJ47450.1 - 0.96 9.2 8.9 1.8 8.3 8.9 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like PAT1 PF09770.9 CDJ47450.1 - 3.3 5.9 26.8 3.8 5.7 26.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAN_4 PF14295.6 CDJ47454.1 - 4.5e-08 32.9 0.7 1.2e-07 31.5 0.7 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 CDJ47454.1 - 2.1e-07 30.8 0.7 2.1e-07 30.8 0.7 1.9 2 0 0 2 2 2 1 PAN domain Endostatin PF06482.11 CDJ47454.1 - 0.0021 17.6 8.7 0.0022 17.5 8.7 1.2 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin FAM60A PF15396.6 CDJ47454.1 - 0.75 9.8 12.4 1.3 9.0 12.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A VIR_N PF15912.5 CDJ47454.1 - 1.1 8.8 11.5 1.6 8.2 11.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF913 PF06025.12 CDJ47454.1 - 1.8 7.4 8.7 2.3 7.1 8.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 CDJ47454.1 - 2.3 7.2 15.8 3.6 6.5 15.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 BORG_CEP PF14957.6 CDJ47454.1 - 3.1 9.0 12.3 4.7 8.4 12.3 1.3 1 0 0 1 1 1 0 Cdc42 effector Gti1_Pac2 PF09729.9 CDJ47454.1 - 4.5 7.3 16.4 6.4 6.8 16.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Med19 PF10278.9 CDJ47454.1 - 4.6 7.1 14.7 6.6 6.6 14.7 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.12 CDJ47454.1 - 4.7 7.0 17.6 6.7 6.4 17.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ47454.1 - 5.4 5.7 22.8 7.5 5.2 22.8 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ47454.1 - 6.4 4.6 21.3 8.6 4.1 21.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Band_3_cyto PF07565.13 CDJ47454.1 - 6.9 6.4 15.6 12 5.6 15.6 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Membralin PF09746.9 CDJ47454.1 - 7.2 5.5 9.1 9.2 5.2 9.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF2722 PF10846.8 CDJ47455.1 - 0.0061 15.6 0.3 0.0061 15.6 0.3 5.4 4 1 2 6 6 6 2 Protein of unknown function (DUF2722) Tfb4 PF03850.14 CDJ47456.1 - 1.1e-24 87.4 7.8 3.7e-16 59.5 0.0 3.1 4 0 0 4 4 4 2 Transcription factor Tfb4 DUF2722 PF10846.8 CDJ47456.1 - 0.0019 17.2 7.5 0.0026 16.8 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ47456.1 - 0.0052 16.4 10.8 0.0078 15.9 10.8 1.2 1 0 0 1 1 1 1 Spt20 family DUF2203 PF09969.9 CDJ47456.1 - 0.043 14.5 1.6 0.079 13.7 1.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF1387 PF07139.11 CDJ47456.1 - 0.4 10.4 4.2 0.57 9.9 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TFIIA PF03153.13 CDJ47456.1 - 2.7 7.9 27.7 7.2 6.5 28.1 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_8 PF13181.6 CDJ47457.1 - 1.8e-06 27.7 0.9 0.0051 16.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ47457.1 - 0.00015 21.6 3.6 0.17 12.1 0.3 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ47457.1 - 0.0008 19.0 0.8 1.3 8.7 0.0 2.9 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.6 CDJ47457.1 - 0.0036 17.6 0.3 2.1 8.9 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ47457.1 - 0.004 17.3 0.2 0.22 11.7 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CDJ47457.1 - 0.005 16.6 11.8 0.02 14.7 0.7 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Ribosomal_60s PF00428.19 CDJ47457.1 - 0.0058 17.2 8.9 0.0058 17.2 8.9 6.8 5 2 1 6 6 5 2 60s Acidic ribosomal protein DUF4148 PF13663.6 CDJ47457.1 - 0.096 12.9 0.1 0.096 12.9 0.1 6.0 5 1 0 5 5 4 0 Domain of unknown function (DUF4148) TPR_7 PF13176.6 CDJ47457.1 - 0.15 12.2 1.7 71 3.8 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat EOS1 PF12326.8 CDJ47457.1 - 0.28 11.1 0.5 2.5 8.0 1.1 2.0 2 1 0 2 2 2 0 N-glycosylation protein DUF4770 PF15994.5 CDJ47457.1 - 0.48 10.6 12.0 0.35 11.1 7.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) FmiP_Thoc5 PF09766.9 CDJ47457.1 - 2.5 7.3 14.9 8.1 5.6 10.1 2.4 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Connexin PF00029.19 CDJ47457.1 - 4.1 7.1 7.5 8.4 6.1 5.8 2.1 2 0 0 2 2 2 0 Connexin Choline_kinase PF01633.20 CDJ47458.1 - 8e-33 113.8 0.0 8e-33 113.8 0.0 2.9 3 0 0 3 3 2 1 Choline/ethanolamine kinase APH PF01636.23 CDJ47458.1 - 3.1e-14 53.5 0.0 3.1e-14 53.5 0.0 3.4 3 0 0 3 3 2 1 Phosphotransferase enzyme family Isy1 PF06246.12 CDJ47458.1 - 0.0032 17.1 26.6 0.0045 16.6 14.1 3.1 3 0 0 3 3 3 2 Isy1-like splicing family DUF2052 PF09747.9 CDJ47458.1 - 0.0039 17.3 33.5 0.0041 17.3 16.0 3.2 3 0 0 3 3 3 2 Coiled-coil domain containing protein (DUF2052) TFIIA PF03153.13 CDJ47458.1 - 0.0048 17.0 85.0 0.13 12.3 14.0 3.2 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 CDJ47458.1 - 0.005 16.5 10.6 0.005 16.5 10.6 3.0 3 0 0 3 3 3 1 Family of unknown function (DUF572) SID-1_RNA_chan PF13965.6 CDJ47458.1 - 0.082 11.3 8.0 1.1 7.5 8.2 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Adaptin_binding PF10199.9 CDJ47458.1 - 0.094 13.3 0.2 0.094 13.3 0.2 2.9 2 2 0 2 2 1 0 Alpha and gamma adaptin binding protein p34 DUF3801 PF12687.7 CDJ47458.1 - 0.2 11.7 28.5 0.085 12.9 15.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3801) CDC45 PF02724.14 CDJ47458.1 - 0.95 7.7 30.3 1 7.6 21.9 3.0 4 0 0 4 4 4 0 CDC45-like protein Neur_chan_memb PF02932.16 CDJ47458.1 - 1 9.3 30.1 3.7 7.5 0.3 2.9 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region EPL1 PF10513.9 CDJ47458.1 - 1.2 9.5 39.4 5.7 7.3 24.9 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like RR_TM4-6 PF06459.12 CDJ47458.1 - 1.8 8.3 42.3 0.061 13.2 23.5 3.1 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ47458.1 - 1.9 7.4 35.1 0.02 13.9 19.9 2.6 3 0 0 3 3 3 0 Solute carrier family 12 PAT1 PF09770.9 CDJ47458.1 - 2 6.6 56.4 0.0071 14.7 32.4 2.8 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 CDJ47458.1 - 3.2 6.6 47.9 0.0092 15.0 23.4 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3807 PF12720.7 CDJ47458.1 - 4.8 7.4 50.1 1.1 9.4 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) BORG_CEP PF14957.6 CDJ47458.1 - 5.6 8.1 25.5 24 6.1 17.7 3.1 3 0 0 3 3 3 0 Cdc42 effector CCSAP PF15748.5 CDJ47458.1 - 6 7.0 42.3 0.035 14.3 21.1 3.0 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated DAG_kinase_N PF14513.6 CDJ47458.1 - 7 6.8 31.4 8.6 6.5 0.1 3.0 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus Ribosomal_60s PF00428.19 CDJ47459.1 - 0.00078 20.0 8.7 0.00078 20.0 8.7 4.1 2 1 1 3 3 3 1 60s Acidic ribosomal protein Rhomboid PF01694.22 CDJ47459.1 - 0.0065 16.5 1.5 0.011 15.8 1.5 1.2 1 0 0 1 1 1 1 Rhomboid family Borrelia_P83 PF05262.11 CDJ47459.1 - 3 6.2 16.2 5.1 5.5 16.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIA PF03153.13 CDJ47460.1 - 2.9e-05 24.3 64.2 3.9e-05 23.8 33.0 2.7 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.11 CDJ47460.1 - 0.013 15.8 15.4 0.013 15.8 15.4 8.3 8 2 0 8 8 8 0 Domain of unknown function (DUF755) BRF1 PF07741.13 CDJ47460.1 - 1.2 9.6 13.0 2 8.8 4.0 2.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Peptidase_S49_N PF08496.10 CDJ47460.1 - 1.4 9.0 10.6 1 9.4 3.8 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal U1snRNP70_N PF12220.8 CDJ47460.1 - 1.6 9.4 10.0 1.3 9.8 1.2 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MAT1 PF06391.13 CDJ47460.1 - 3.3 7.5 20.8 8.8 6.1 1.4 2.6 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Nop25 PF09805.9 CDJ47460.1 - 4.2 7.8 19.9 3.8 8.0 10.5 2.7 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) PAT1 PF09770.9 CDJ47460.1 - 6.3 4.9 31.5 1.5 7.0 14.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RskA PF10099.9 CDJ47463.1 - 0.014 15.7 19.4 0.014 15.7 19.4 6.9 4 2 1 5 5 5 0 Anti-sigma-K factor rskA DUF3487 PF11990.8 CDJ47463.1 - 0.027 14.3 1.7 0.039 13.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) OAD_gamma PF04277.13 CDJ47463.1 - 0.49 11.0 0.1 0.49 11.0 0.1 8.6 6 2 2 8 8 8 0 Oxaloacetate decarboxylase, gamma chain MAT1 PF06391.13 CDJ47463.1 - 1.2 8.9 20.6 1.1 9.1 3.7 2.5 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Peptidase_S49_N PF08496.10 CDJ47463.1 - 2.1 8.4 17.2 4.6 7.3 4.8 2.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Activator_LAG-3 PF11498.8 CDJ47465.1 - 0.98 8.3 17.9 0.37 9.7 15.3 1.6 1 1 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ47465.1 - 1.2 9.1 18.6 1.5 8.7 18.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ47465.1 - 2 7.5 4.5 2.2 7.3 4.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF4551 PF15087.6 CDJ47465.1 - 7 5.3 5.9 7.7 5.2 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sod_Fe_C PF02777.18 CDJ47466.1 - 1.2e-18 67.1 0.0 1.2e-18 67.1 0.0 3.4 4 2 1 5 5 5 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CDJ47466.1 - 0.012 16.1 0.0 0.012 16.1 0.0 3.7 2 1 1 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Utp14 PF04615.13 CDJ47466.1 - 1.6 7.2 41.1 0.017 13.7 28.3 3.1 3 0 0 3 3 3 0 Utp14 protein RskA PF10099.9 CDJ47467.1 - 2.5e-06 27.9 6.6 2.5e-06 27.9 6.6 4.2 1 1 2 4 4 3 2 Anti-sigma-K factor rskA LMBR1 PF04791.16 CDJ47467.1 - 0.0019 17.2 5.4 0.0038 16.2 5.4 1.4 1 0 0 1 1 1 1 LMBR1-like membrane protein CDC45 PF02724.14 CDJ47467.1 - 0.036 12.4 19.1 0.017 13.5 13.1 2.0 2 0 0 2 2 2 0 CDC45-like protein Menin PF05053.13 CDJ47467.1 - 0.053 11.9 19.5 0.071 11.5 19.5 1.2 1 0 0 1 1 1 0 Menin YbhQ PF11076.8 CDJ47467.1 - 0.47 10.5 3.0 0.96 9.5 3.0 1.5 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ MDM10 PF12519.8 CDJ47467.1 - 0.73 8.6 28.2 6.4 5.5 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 GREB1 PF15782.5 CDJ47467.1 - 0.92 6.5 32.3 1.3 6.0 32.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SMYLE_N PF18615.1 CDJ47467.1 - 1.4 8.4 22.9 0.37 10.3 15.6 2.1 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain CAC1F_C PF16885.5 CDJ47467.1 - 2 8.0 26.7 3.3 7.3 26.7 1.3 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Utp14 PF04615.13 CDJ47467.1 - 3.2 6.2 35.2 4.6 5.7 35.2 1.1 1 0 0 1 1 1 0 Utp14 protein Nucleo_P87 PF07267.11 CDJ47467.1 - 5.2 5.8 22.0 6.8 5.4 22.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sec62 PF03839.16 CDJ47467.1 - 9.9 5.6 25.3 1.8 8.0 16.5 2.5 2 0 0 2 2 2 0 Translocation protein Sec62 PAT1 PF09770.9 CDJ47468.1 - 0.022 13.1 38.6 0.026 12.8 38.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MAP7 PF05672.11 CDJ47469.1 - 0.14 11.8 37.6 0.02 14.6 28.2 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family LAP1C PF05609.12 CDJ47469.1 - 0.16 11.1 41.5 0.22 10.6 41.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4746 PF15928.5 CDJ47469.1 - 3.2 7.1 16.0 3 7.2 15.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) SMYLE_N PF18615.1 CDJ47469.1 - 8 5.9 33.8 11 5.5 33.8 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain ClpS PF02617.17 CDJ47470.1 - 0.2 11.5 1.1 1.5 8.6 0.1 2.7 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS Utp14 PF04615.13 CDJ47470.1 - 1 7.9 29.2 1.8 7.0 29.2 1.5 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.14 CDJ47470.1 - 1.4 7.1 22.0 2.6 6.2 22.0 1.5 1 0 0 1 1 1 0 CDC45-like protein Endostatin PF06482.11 CDJ47471.1 - 0.001 18.6 11.0 0.0017 17.9 11.0 1.3 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Tim54 PF11711.8 CDJ47471.1 - 0.0097 14.7 8.1 0.016 14.0 8.1 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 PepSY_TM PF03929.16 CDJ47471.1 - 0.011 15.5 9.6 0.012 15.3 2.3 2.3 2 0 0 2 2 2 0 PepSY-associated TM region CCSAP PF15748.5 CDJ47471.1 - 0.023 14.9 15.1 0.035 14.3 15.1 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SAGA-Tad1 PF12767.7 CDJ47471.1 - 0.024 14.4 11.5 0.033 13.9 11.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF913 PF06025.12 CDJ47471.1 - 0.029 13.4 2.5 0.037 13.0 2.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Suf PF05843.14 CDJ47471.1 - 0.036 14.0 18.1 0.064 13.2 18.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BPL_N PF09825.9 CDJ47471.1 - 0.045 12.8 6.7 0.058 12.5 6.7 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Ndc1_Nup PF09531.10 CDJ47471.1 - 0.052 12.2 9.6 0.016 13.9 6.8 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 CDJ47471.1 - 0.34 10.7 17.3 0.5 10.2 17.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Afi1 PF07792.12 CDJ47471.1 - 0.36 11.3 15.5 0.61 10.6 15.5 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.14 CDJ47471.1 - 0.45 8.7 12.4 0.58 8.4 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PAT1 PF09770.9 CDJ47471.1 - 0.53 8.5 29.7 0.76 8.0 29.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ47471.1 - 0.8 8.9 9.0 0.018 14.3 2.7 1.4 2 0 0 2 2 1 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ47471.1 - 0.87 8.3 23.4 1.3 7.7 23.4 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ47471.1 - 1 8.3 17.4 1.3 7.9 17.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Glyco_transf_41 PF13844.6 CDJ47471.1 - 1.1 7.6 4.3 1.4 7.2 4.3 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 PIP5K PF01504.18 CDJ47471.1 - 1.3 8.2 9.3 2 7.6 9.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CDC27 PF09507.10 CDJ47471.1 - 1.5 8.1 21.5 0.045 13.1 15.5 1.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Gti1_Pac2 PF09729.9 CDJ47471.1 - 1.6 8.8 11.7 2.6 8.1 11.7 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Myc_N PF01056.18 CDJ47471.1 - 1.6 8.5 16.6 0.36 10.7 11.5 1.8 1 1 0 2 2 2 0 Myc amino-terminal region SID-1_RNA_chan PF13965.6 CDJ47471.1 - 2.4 6.5 3.2 2.7 6.3 3.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4746 PF15928.5 CDJ47471.1 - 3.3 7.0 13.4 4.9 6.5 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) XRN_M PF17846.1 CDJ47471.1 - 3.5 6.5 11.9 5 6.0 11.9 1.2 1 0 0 1 1 1 0 Xrn1 helical domain LMBR1 PF04791.16 CDJ47471.1 - 3.9 6.3 5.0 4.5 6.1 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GREB1 PF15782.5 CDJ47471.1 - 3.9 4.5 14.7 4.8 4.2 14.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM60A PF15396.6 CDJ47471.1 - 4.2 7.3 15.5 6.5 6.7 15.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 CDJ47471.1 - 4.9 5.1 16.3 6.2 4.8 16.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 CDJ47471.1 - 5.6 7.0 14.4 8.6 6.3 14.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IER PF05760.12 CDJ47471.1 - 6.7 6.9 23.4 0.7 10.1 16.0 2.1 2 0 0 2 2 2 0 Immediate early response protein (IER) BORG_CEP PF14957.6 CDJ47471.1 - 7.7 7.7 12.8 13 6.9 12.8 1.4 1 0 0 1 1 1 0 Cdc42 effector Exonuc_VII_L PF02601.15 CDJ47471.1 - 8.3 5.9 22.5 13 5.2 22.7 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit NPR3 PF03666.13 CDJ47471.1 - 8.6 5.0 18.5 11 4.6 18.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CSG2 PF16965.5 CDJ47471.1 - 9 5.1 7.1 14 4.5 7.1 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Membralin PF09746.9 CDJ47471.1 - 9.1 5.2 12.2 13 4.7 12.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein Joubert PF15392.6 CDJ47472.1 - 0.26 11.0 8.4 0.31 10.7 8.4 1.0 1 0 0 1 1 1 0 Joubert syndrome-associated Apt1 PF10351.9 CDJ47472.1 - 0.87 8.4 13.7 0.92 8.3 13.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ47472.1 - 1.1 9.1 13.8 1.3 8.9 13.8 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CDJ47472.1 - 1.1 7.7 14.7 1.3 7.5 14.7 1.1 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 CDJ47472.1 - 2.7 7.2 11.7 3.8 6.7 11.7 1.2 1 0 0 1 1 1 0 BUD22 FAP206 PF12018.8 CDJ47473.1 - 2.2e-10 40.5 0.3 2.2e-10 40.5 0.3 2.7 2 2 0 2 2 2 1 Domain of unknown function DUF755 PF05501.11 CDJ47473.1 - 0.0023 18.2 3.3 0.0023 18.2 3.3 5.9 5 1 0 5 5 5 1 Domain of unknown function (DUF755) Leucyl-specific PF14795.6 CDJ47473.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain FAM104 PF15434.6 CDJ47473.1 - 0.99 10.0 13.8 2.7 8.6 0.9 2.9 2 0 0 2 2 2 0 Family 104 Proteasome PF00227.26 CDJ47474.1 - 4.7e-12 45.8 0.6 2.3e-08 33.8 0.1 3.5 2 1 0 2 2 2 2 Proteasome subunit TFIIA PF03153.13 CDJ47474.1 - 0.00016 21.8 10.6 0.00019 21.5 10.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PIP5K PF01504.18 CDJ47474.1 - 0.00046 19.5 0.4 0.00058 19.2 0.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MRP-S25 PF13741.6 CDJ47474.1 - 0.00055 19.6 0.5 0.00079 19.0 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 DUF2722 PF10846.8 CDJ47474.1 - 0.0016 17.5 10.6 0.0016 17.5 10.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ47474.1 - 0.0038 17.3 3.1 0.0047 16.9 3.1 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) MCU PF04678.13 CDJ47474.1 - 0.0055 16.8 0.4 0.01 15.9 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Presenilin PF01080.17 CDJ47474.1 - 0.0062 15.4 2.6 0.0075 15.1 2.6 1.1 1 0 0 1 1 1 1 Presenilin AF-4 PF05110.13 CDJ47474.1 - 0.0068 14.6 10.3 0.0099 14.0 10.3 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein TCP PF03634.13 CDJ47474.1 - 0.0069 17.0 4.5 0.011 16.3 4.5 1.3 1 0 0 1 1 1 1 TCP family transcription factor CCDC53 PF10152.9 CDJ47474.1 - 0.016 15.6 3.0 0.085 13.3 1.6 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex eIF-3_zeta PF05091.12 CDJ47474.1 - 0.045 12.7 4.9 0.055 12.5 4.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF913 PF06025.12 CDJ47474.1 - 0.076 12.0 0.7 0.11 11.5 0.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1645 PF07816.11 CDJ47474.1 - 0.078 13.5 4.9 1 9.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Neur_chan_memb PF02932.16 CDJ47474.1 - 0.11 12.5 0.2 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 CDJ47474.1 - 0.13 10.2 1.6 0.14 10.0 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4770 PF15994.5 CDJ47474.1 - 0.14 12.4 3.8 0.23 11.7 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Connexin PF00029.19 CDJ47474.1 - 0.15 11.8 0.6 0.19 11.5 0.6 1.2 1 0 0 1 1 1 0 Connexin Spt20 PF12090.8 CDJ47474.1 - 0.37 10.4 24.3 0.67 9.5 24.3 1.3 1 0 0 1 1 1 0 Spt20 family Herpes_pp85 PF04637.12 CDJ47474.1 - 0.94 7.8 4.2 1.4 7.3 4.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4834 PF16118.5 CDJ47474.1 - 1.1 10.3 10.7 0.28 12.2 7.3 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) DUF4628 PF15429.6 CDJ47474.1 - 2.3 7.8 8.9 0.072 12.8 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) DUF775 PF05603.12 CDJ47474.1 - 2.8 7.4 8.6 5.8 6.4 6.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Proteasome PF00227.26 CDJ47475.1 - 0.00012 21.7 0.1 0.00015 21.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Spt20 PF12090.8 CDJ47476.1 - 0.00063 19.4 14.7 0.00067 19.3 14.7 1.0 1 0 0 1 1 1 1 Spt20 family SUIM_assoc PF16619.5 CDJ47476.1 - 0.01 15.9 18.4 0.074 13.1 9.5 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RusA PF05866.11 CDJ47476.1 - 0.019 15.5 0.6 0.024 15.2 0.6 1.3 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA DUF4366 PF14283.6 CDJ47476.1 - 0.035 14.2 2.6 0.041 13.9 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) AP3D1 PF06375.11 CDJ47476.1 - 0.056 13.7 3.5 0.066 13.5 3.5 1.0 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Pex14_N PF04695.13 CDJ47476.1 - 0.063 13.9 9.3 0.078 13.6 9.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Plasmid_parti PF01672.16 CDJ47476.1 - 0.092 13.4 0.7 0.11 13.1 0.7 1.2 1 0 0 1 1 1 0 Putative plasmid partition protein IER PF05760.12 CDJ47476.1 - 0.12 12.7 9.2 0.14 12.4 9.2 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) TFIIA PF03153.13 CDJ47476.1 - 0.23 11.4 15.7 0.27 11.2 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ANAPC_CDC26 PF10471.9 CDJ47476.1 - 0.24 12.3 19.6 2 9.3 7.9 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 RskA PF10099.9 CDJ47476.1 - 0.41 10.9 18.7 0.54 10.5 10.3 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA BRF1 PF07741.13 CDJ47476.1 - 0.54 10.6 4.6 0.69 10.3 4.6 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain GREB1 PF15782.5 CDJ47476.1 - 0.9 6.6 7.8 0.98 6.5 7.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer COX14 PF14880.6 CDJ47476.1 - 1.1 9.1 5.5 13 5.8 2.6 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Presenilin PF01080.17 CDJ47476.1 - 1.8 7.3 6.5 2 7.1 6.5 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 CDJ47476.1 - 2.4 7.7 9.5 2.9 7.4 9.5 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MITF_TFEB_C_3_N PF15951.5 CDJ47476.1 - 3.8 8.1 19.0 1.1 9.9 1.1 2.1 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus Mlh1_C PF16413.5 CDJ47477.1 - 3.8e-38 131.4 0.7 3.8e-38 131.4 0.7 3.9 2 1 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus SR-25 PF10500.9 CDJ47477.1 - 0.0042 16.7 8.4 0.0042 16.7 8.4 7.9 3 2 3 7 7 7 2 Nuclear RNA-splicing-associated protein V_ATPase_I PF01496.19 CDJ47478.1 - 0.0009 17.3 25.5 0.0011 17.0 25.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family AF-4 PF05110.13 CDJ47478.1 - 0.074 11.1 44.8 0.1 10.7 44.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.11 CDJ47478.1 - 0.17 10.1 7.0 0.21 9.9 7.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SAPS PF04499.15 CDJ47478.1 - 0.24 10.1 21.1 0.35 9.6 21.1 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 CDJ47478.1 - 0.26 9.4 32.4 0.29 9.2 32.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hamartin PF04388.12 CDJ47478.1 - 0.71 8.5 35.0 0.77 8.3 35.0 1.2 1 0 0 1 1 1 0 Hamartin protein Asp-B-Hydro_N PF05279.11 CDJ47478.1 - 0.98 9.4 23.7 1.5 8.8 23.7 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FapA PF03961.13 CDJ47478.1 - 1 7.9 17.5 1.2 7.7 17.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TIP41 PF04176.13 CDJ47478.1 - 1.4 8.4 0.0 1.4 8.4 0.0 3.0 2 1 0 2 2 1 0 TIP41-like family Herpes_pp85 PF04637.12 CDJ47478.1 - 1.6 7.1 11.5 2.3 6.5 11.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Nop53 PF07767.11 CDJ47478.1 - 2.1 7.6 40.6 4.4 6.6 40.6 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PA26 PF04636.13 CDJ47478.1 - 2.5 6.9 28.7 3.5 6.5 28.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GREB1 PF15782.5 CDJ47478.1 - 2.9 4.9 39.7 3.4 4.6 39.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDJ47478.1 - 5.5 5.4 31.6 8.2 4.8 31.6 1.3 1 0 0 1 1 1 0 Macoilin family CDK5_activator PF03261.15 CDJ47478.1 - 7.2 6.0 31.3 9.5 5.7 31.3 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein LMBR1 PF04791.16 CDJ47478.1 - 7.6 5.3 19.4 10 4.9 19.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Apt1 PF10351.9 CDJ47479.1 - 4 6.2 0.0 4 6.2 0.0 19.9 16 4 0 16 16 16 0 Golgi-body localisation protein domain DnaJ_C PF01556.18 CDJ47480.1 - 1.5e-32 112.7 0.1 2.2e-32 112.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ47480.1 - 5.8e-23 80.8 1.8 9.2e-23 80.2 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDJ47480.1 - 7.4e-13 48.7 16.9 7.4e-13 48.7 16.9 1.9 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.19 CDJ47480.1 - 0.57 10.2 10.8 2.3 8.3 0.5 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 CDJ47480.1 - 1.7 8.7 14.2 1.9 8.5 2.5 3.0 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Tnp_zf-ribbon_2 PF13842.6 CDJ47480.1 - 2.9 8.8 12.9 1.9 9.3 0.1 3.5 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon RRM_1 PF00076.22 CDJ47481.1 - 1e-09 38.0 0.0 2.5e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ47481.1 - 0.0046 16.9 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif HEAT_2 PF13646.6 CDJ47482.1 - 0.0017 18.7 10.6 0.85 10.1 0.2 5.0 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.22 CDJ47482.1 - 0.0027 17.8 18.4 0.019 15.2 0.1 7.1 7 1 1 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 CDJ47482.1 - 1.2 9.7 20.3 3.2 8.4 0.3 6.2 6 1 1 7 7 7 0 HEAT-like repeat V-SNARE_C PF12352.8 CDJ47483.1 - 2.4e-14 53.4 0.2 5.9e-14 52.1 0.2 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CDJ47483.1 - 0.0011 18.9 0.1 0.002 18.0 0.1 1.4 1 0 0 1 1 1 1 Sec20 Kelch_5 PF13854.6 CDJ47483.1 - 0.24 11.4 0.5 5.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Peptidase_S8 PF00082.22 CDJ47484.1 - 1.2e-42 146.2 0.1 3.3e-42 144.8 0.1 1.6 1 0 0 1 1 1 1 Subtilase family Peptidase_C50 PF03568.17 CDJ47484.1 - 0.00044 19.5 0.0 0.0009 18.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 EGF_3 PF12947.7 CDJ47484.1 - 0.061 13.5 19.3 0.11 12.7 4.9 2.8 2 0 0 2 2 2 0 EGF domain Cu-binding_MopE PF11617.8 CDJ47484.1 - 0.5 10.6 3.1 1.2 9.3 3.1 1.7 1 0 0 1 1 1 0 Putative metal-binding motif S_locus_glycop PF00954.20 CDJ47484.1 - 8.2 7.0 11.1 0.11 13.1 1.7 2.5 2 0 0 2 2 2 0 S-locus glycoprotein domain SF-assemblin PF06705.11 CDJ47485.1 - 2.3e-29 102.5 16.3 2.8e-29 102.2 16.3 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Baculo_PEP_C PF04513.12 CDJ47485.1 - 0.03 14.4 0.6 0.03 14.4 0.6 3.4 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus betaPIX_CC PF16523.5 CDJ47485.1 - 0.72 9.7 7.7 6.2 6.7 1.8 3.0 2 1 0 2 2 2 0 betaPIX coiled coil Rab_bind PF16704.5 CDJ47485.1 - 0.94 9.5 6.6 0.57 10.3 0.9 3.2 2 1 2 4 4 4 0 Rab binding domain FBPase PF00316.20 CDJ47487.1 - 6.3e-31 107.3 0.0 9.7e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Peptidase_M24 PF00557.24 CDJ47488.1 - 1.4e-54 185.0 0.0 2.2e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CDJ47488.1 - 9.7e-13 47.9 0.0 1.8e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain FA_desaturase_2 PF03405.14 CDJ47488.1 - 0.049 12.5 0.1 0.08 11.8 0.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF3793 PF12672.7 CDJ47488.1 - 0.098 12.7 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Ank_2 PF12796.7 CDJ47489.1 - 7.3e-07 29.7 0.1 2.4e-05 24.8 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ47489.1 - 7.2e-06 26.4 0.0 0.086 13.5 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ47489.1 - 0.00017 21.8 0.1 0.095 13.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ47489.1 - 0.0011 19.3 0.0 0.66 10.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CDJ47489.1 - 0.01 16.3 0.0 1.3 9.9 0.0 3.1 3 1 0 3 3 3 0 Ankyrin repeat Pap_E4 PF02711.14 CDJ47489.1 - 0.016 16.2 3.0 0.37 11.8 2.0 2.3 2 0 0 2 2 2 0 E4 protein Peptidase_C48 PF02902.19 CDJ47490.1 - 1.5e-19 70.7 0.0 4e-19 69.3 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Memo PF01875.17 CDJ47493.1 - 2.2e-52 177.9 0.0 1e-48 165.9 0.0 2.0 1 1 1 2 2 2 2 Memo-like protein TFIIA PF03153.13 CDJ47494.1 - 0.0059 16.6 65.6 0.12 12.4 9.9 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 CDJ47494.1 - 0.016 15.1 19.4 0.2 11.6 14.6 2.1 2 0 0 2 2 2 0 Velvet factor Endostatin PF06482.11 CDJ47494.1 - 0.35 10.3 22.1 0.086 12.3 13.9 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin SID-1_RNA_chan PF13965.6 CDJ47494.1 - 0.37 9.2 2.5 0.87 7.9 2.3 1.6 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 SpoIIIAH PF12685.7 CDJ47494.1 - 0.39 10.5 22.6 0.83 9.4 14.5 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF572 PF04502.13 CDJ47494.1 - 0.44 10.1 20.3 0.26 10.9 13.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) SLC12 PF03522.15 CDJ47494.1 - 1.8 7.5 25.7 0.31 10.0 19.9 1.9 2 0 0 2 2 2 0 Solute carrier family 12 DUF4228 PF14009.6 CDJ47494.1 - 5 7.5 23.1 4.1 7.8 3.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Ran-binding PF05508.11 CDJ47497.1 - 0.15 11.0 1.0 0.22 10.4 1.0 1.2 1 0 0 1 1 1 0 RanGTP-binding protein DUF2057 PF09829.9 CDJ47497.1 - 4.8 7.3 13.2 1.7 8.7 1.9 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) AAA_23 PF13476.6 CDJ47498.1 - 0.0046 17.5 0.4 0.0046 17.5 0.4 5.8 5 1 0 5 5 5 2 AAA domain Ctr PF04145.15 CDJ47499.1 - 8.5e-09 36.2 1.1 8.5e-09 36.2 1.1 2.4 2 2 0 2 2 2 1 Ctr copper transporter family 5TM-5TMR_LYT PF07694.12 CDJ47499.1 - 5.6 6.4 6.3 1.8 8.1 2.5 1.9 1 1 1 2 2 2 0 5TMR of 5TMR-LYT Presenilin PF01080.17 CDJ47500.1 - 9.4e-05 21.3 28.1 9.4e-05 21.3 28.1 3.1 3 0 0 3 3 3 2 Presenilin Macoilin PF09726.9 CDJ47500.1 - 0.00072 18.3 35.5 0.00072 18.3 35.5 2.2 2 0 0 2 2 1 1 Macoilin family SID-1_RNA_chan PF13965.6 CDJ47500.1 - 0.00084 17.9 8.0 0.00084 17.9 8.0 1.8 2 0 0 2 2 2 1 dsRNA-gated channel SID-1 ASC PF00858.24 CDJ47500.1 - 0.0016 17.5 3.0 0.0016 17.5 3.0 1.9 3 0 0 3 3 3 1 Amiloride-sensitive sodium channel PAT1 PF09770.9 CDJ47500.1 - 0.15 10.4 64.8 0.041 12.2 45.4 2.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Mem_trans PF03547.18 CDJ47500.1 - 0.15 10.4 5.3 0.098 11.0 0.5 2.3 2 0 0 2 2 2 0 Membrane transport protein HEPN_Toprim_N PF18871.1 CDJ47500.1 - 2.1 8.2 9.4 0.95 9.3 6.8 1.7 2 0 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 Pkinase_fungal PF17667.1 CDJ47500.1 - 2.4 6.8 22.3 0.021 13.6 10.2 2.7 3 0 0 3 3 3 0 Fungal protein kinase DAG_kinase_N PF14513.6 CDJ47500.1 - 2.7 8.2 38.6 1.4 9.1 25.1 3.5 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus GAGA_bind PF06217.12 CDJ47500.1 - 3 8.0 32.5 5.7 7.1 25.8 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family FAM60A PF15396.6 CDJ47500.1 - 4.4 7.3 42.3 0.78 9.7 27.8 3.1 3 0 0 3 3 3 0 Protein Family FAM60A V_ATPase_I PF01496.19 CDJ47500.1 - 4.8 5.0 39.1 0.015 13.2 24.4 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 CDJ47501.1 - 0.16 11.0 15.2 0.55 9.2 0.5 2.2 2 0 0 2 2 2 0 Solute carrier family 12 SPX PF03105.19 CDJ47501.1 - 1.3 8.9 34.9 0.04 13.8 15.3 2.1 2 0 0 2 2 2 0 SPX domain Apt1 PF10351.9 CDJ47501.1 - 7.5 5.3 34.8 0.26 10.1 20.2 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain zf-C2HC_2 PF13913.6 CDJ47502.1 - 9.3e-08 31.8 20.5 8e-06 25.6 7.1 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type SR-25 PF10500.9 CDJ47502.1 - 4.5e-05 23.2 15.8 4.5e-05 23.2 15.8 21.8 12 7 10 22 22 22 5 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ47502.1 - 0.02 13.9 0.2 0.02 13.9 0.2 31.1 8 6 12 23 23 23 0 Protein of unknown function (DUF2722) Mito_carr PF00153.27 CDJ47502.1 - 0.045 13.7 19.7 0.89 9.5 0.0 6.2 5 0 0 5 5 5 0 Mitochondrial carrier protein Transposase_21 PF02992.14 CDJ47502.1 - 4.4 6.5 9.0 5.3 6.2 4.6 3.0 2 0 0 2 2 2 0 Transposase family tnp2 Kinesin PF00225.23 CDJ47503.1 - 2.6e-30 105.5 2.1 6.9e-29 100.8 0.0 3.1 2 1 0 2 2 2 1 Kinesin motor domain FHA PF00498.26 CDJ47503.1 - 0.00072 19.8 3.1 0.0038 17.5 3.1 2.1 1 1 0 1 1 1 1 FHA domain Trp_oprn_chp PF09534.10 CDJ47503.1 - 0.0031 17.3 0.3 0.0031 17.3 0.3 2.3 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2722 PF10846.8 CDJ47503.1 - 0.029 13.3 11.8 0.043 12.8 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ47503.1 - 0.031 13.0 2.6 0.04 12.7 2.6 1.2 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 CDJ47503.1 - 0.18 11.2 2.8 0.32 10.3 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM176 PF14851.6 CDJ47503.1 - 0.18 11.5 2.5 0.41 10.3 2.5 1.5 1 0 0 1 1 1 0 FAM176 family Connexin PF00029.19 CDJ47503.1 - 0.47 10.2 1.5 0.77 9.5 1.5 1.3 1 0 0 1 1 1 0 Connexin DDHD PF02862.17 CDJ47503.1 - 0.68 10.1 4.7 1.1 9.3 4.3 1.5 1 1 0 1 1 1 0 DDHD domain TERB2 PF15101.6 CDJ47503.1 - 0.75 9.8 11.5 4.5 7.3 10.4 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 eIF-3_zeta PF05091.12 CDJ47503.1 - 0.93 8.4 6.8 1.4 7.8 6.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ47503.1 - 1 10.4 7.8 2.7 9.0 7.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2681 PF10883.8 CDJ47503.1 - 2 8.9 15.2 0.97 9.9 10.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Spt20 PF12090.8 CDJ47503.1 - 2.7 7.5 25.3 0.71 9.4 22.2 1.5 2 0 0 2 2 2 0 Spt20 family Jak1_Phl PF17887.1 CDJ47503.1 - 3.7 7.5 8.4 8.9 6.3 3.6 2.2 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain CLN3 PF02487.17 CDJ47503.1 - 5.2 6.0 6.4 0.28 10.2 1.0 1.5 2 0 0 2 2 2 0 CLN3 protein Isy1 PF06246.12 CDJ47504.1 - 5.4e-26 91.7 41.7 2e-15 57.0 38.6 3.5 2 1 0 2 2 2 2 Isy1-like splicing family Bax1-I PF01027.20 CDJ47505.1 - 1.5 8.6 12.8 2.2 8.1 12.8 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 SUIM_assoc PF16619.5 CDJ47507.1 - 1.4e-06 28.2 0.7 9.4 6.4 0.0 3.2 2 2 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 HTH_29 PF13551.6 CDJ47507.1 - 0.017 15.1 0.1 0.047 13.7 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix EF-hand_like PF09279.11 CDJ47507.1 - 0.055 14.0 1.6 0.12 12.9 1.6 1.6 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Fis1_TPR_N PF14852.6 CDJ47507.1 - 0.078 12.7 0.3 0.24 11.1 0.3 1.8 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat HTH_28 PF13518.6 CDJ47507.1 - 0.39 10.9 0.0 0.39 10.9 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain Dehydrin PF00257.19 CDJ47507.1 - 1.8 9.1 11.8 0.1 13.2 5.2 2.0 1 1 0 2 2 2 0 Dehydrin Ribosomal_60s PF00428.19 CDJ47508.1 - 1 10.0 13.7 1.6 9.3 13.6 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein GAGA_bind PF06217.12 CDJ47509.1 - 0.36 11.1 22.8 0.43 10.8 22.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Hamartin PF04388.12 CDJ47509.1 - 0.66 8.6 40.5 0.9 8.1 40.5 1.1 1 0 0 1 1 1 0 Hamartin protein PAT1 PF09770.9 CDJ47509.1 - 5.8 5.1 51.0 7.8 4.6 51.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Caldesmon PF02029.15 CDJ47509.1 - 8.9 4.9 36.2 14 4.3 36.2 1.3 1 0 0 1 1 1 0 Caldesmon DnaJ_CXXCXGXG PF00684.19 CDJ47510.1 - 1.5e-10 41.3 12.8 2.9e-10 40.4 12.8 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CDJ47510.1 - 1.6e-05 24.8 14.2 0.0018 18.2 3.4 2.6 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DnaJ_C PF01556.18 CDJ47510.1 - 0.16 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 DnaJ C terminal domain DnaJ PF00226.31 CDJ47510.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 DnaJ domain IMUP PF15761.5 CDJ47510.1 - 5.5 7.7 10.4 6.6 7.5 2.6 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein Med15 PF09606.10 CDJ47511.1 - 0.001 17.9 8.9 0.001 17.9 8.9 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal FAM176 PF14851.6 CDJ47511.1 - 0.0026 17.4 0.1 0.0029 17.3 0.1 1.1 1 0 0 1 1 1 1 FAM176 family Hydin_ADK PF17213.3 CDJ47511.1 - 0.023 15.0 0.6 0.027 14.8 0.6 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain TERB2 PF15101.6 CDJ47511.1 - 0.025 14.6 3.8 0.027 14.5 3.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2126 PF09899.9 CDJ47511.1 - 0.032 12.3 0.3 0.032 12.3 0.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) TMEM51 PF15345.6 CDJ47511.1 - 0.045 13.6 5.3 0.054 13.3 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 TFIIA PF03153.13 CDJ47511.1 - 0.055 13.5 10.7 0.056 13.4 10.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF775 PF05603.12 CDJ47511.1 - 0.056 13.0 1.7 0.06 12.9 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF2722 PF10846.8 CDJ47511.1 - 0.062 12.2 11.6 0.065 12.2 11.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF3464 PF11947.8 CDJ47511.1 - 0.062 13.0 2.0 0.073 12.8 2.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Spt20 PF12090.8 CDJ47511.1 - 0.063 12.9 16.2 0.071 12.7 16.2 1.1 1 0 0 1 1 1 0 Spt20 family MDM10 PF12519.8 CDJ47511.1 - 0.098 11.5 0.5 0.11 11.4 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF3506 PF12014.8 CDJ47511.1 - 0.1 12.6 1.5 0.12 12.3 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) DUF4834 PF16118.5 CDJ47511.1 - 0.16 12.9 4.1 0.22 12.5 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ47511.1 - 0.23 10.2 2.2 0.24 10.1 2.2 1.0 1 0 0 1 1 1 0 Presenilin MscS_TM PF12794.7 CDJ47511.1 - 0.35 9.7 4.2 0.41 9.5 4.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Roughex PF06020.11 CDJ47511.1 - 3.9 6.5 10.7 4.3 6.4 10.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Androgen_recep PF02166.16 CDJ47511.1 - 6.7 5.4 14.1 7.6 5.3 14.1 1.2 1 0 0 1 1 1 0 Androgen receptor Activator_LAG-3 PF11498.8 CDJ47511.1 - 9.1 5.1 24.0 10 4.9 24.0 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TMEM220 PF15071.6 CDJ47513.1 - 0.042 14.6 0.3 0.11 13.3 0.1 1.7 2 0 0 2 2 2 0 Transmembrane family 220, helix Ank_2 PF12796.7 CDJ47514.1 - 1.9e-12 47.6 3.5 1.3e-05 25.7 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ47514.1 - 1.2e-08 35.0 15.0 0.013 15.9 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 CDJ47514.1 - 2.1e-08 34.6 1.3 0.039 14.6 0.1 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ47514.1 - 2.3e-08 33.6 7.6 0.015 15.8 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 CDJ47514.1 - 0.0002 21.6 2.6 1.9 8.9 0.1 4.5 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Patched PF02460.18 CDJ47515.1 - 4.5e-84 283.0 20.1 1.2e-39 136.1 14.9 4.1 3 2 1 4 4 4 3 Patched family Sterol-sensing PF12349.8 CDJ47515.1 - 5.8e-27 94.4 3.6 5.8e-27 94.4 3.6 2.4 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 CDJ47515.1 - 1.3e-06 26.4 10.2 1.3e-06 26.4 10.2 1.8 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Spt20 PF12090.8 CDJ47516.1 - 0.0015 18.2 2.5 0.0015 18.2 2.5 3.8 4 0 0 4 4 4 2 Spt20 family SUIM_assoc PF16619.5 CDJ47516.1 - 0.0017 18.4 37.4 0.3 11.2 0.1 5.9 6 0 0 6 6 6 5 Unstructured region C-term to UIM in Ataxin3 DUF2380 PF09533.10 CDJ47516.1 - 9.2 5.8 7.6 1.1 8.9 2.2 2.2 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) SR-25 PF10500.9 CDJ47518.1 - 0.039 13.6 35.6 1.3 8.6 18.4 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.19 CDJ47518.1 - 0.16 12.6 26.3 1.6 9.4 16.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein IMUP PF15761.5 CDJ47518.1 - 0.55 10.9 32.0 2.2 9.0 15.9 2.3 1 1 1 2 2 2 0 Immortalisation up-regulated protein RskA PF10099.9 CDJ47518.1 - 1.1 9.5 40.6 4.7e+03 -2.3 40.6 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA C_Hendra PF16821.5 CDJ47518.1 - 1.1 9.1 13.6 1.6 8.6 13.6 1.1 1 0 0 1 1 1 0 C protein from hendra and measles viruses ASD2 PF08687.11 CDJ47518.1 - 1.3 8.5 14.5 1.6 8.2 14.5 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 YL1 PF05764.13 CDJ47518.1 - 2 8.5 20.8 2.4 8.2 20.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Suf PF05843.14 CDJ47518.1 - 2.9 7.8 20.2 3.7 7.5 20.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PPP4R2 PF09184.11 CDJ47518.1 - 5.7 6.4 12.3 6.1 6.4 12.3 1.1 1 0 0 1 1 1 0 PPP4R2 PA26 PF04636.13 CDJ47518.1 - 6.4 5.6 12.1 7 5.5 12.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Peptidase_S64 PF08192.11 CDJ47518.1 - 6.5 5.1 18.7 7.1 5.0 18.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 SPX PF03105.19 CDJ47518.1 - 7.3 6.4 22.6 8.4 6.2 22.6 1.1 1 0 0 1 1 1 0 SPX domain RIFIN PF02009.16 CDJ47518.1 - 8.7 6.1 14.6 12 5.7 14.6 1.2 1 0 0 1 1 1 0 Rifin RAP1 PF07218.11 CDJ47518.1 - 9.1 4.4 21.8 10 4.2 21.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3591 PF12157.8 CDJ47519.1 - 3.5e-16 58.9 13.1 1.3e-09 37.2 0.1 4.8 3 2 1 4 4 4 2 Protein of unknown function (DUF3591) Bromodomain PF00439.25 CDJ47519.1 - 1.8e-15 56.7 0.0 3.5e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain TFIIA PF03153.13 CDJ47519.1 - 3.3e-15 57.0 91.4 5.5e-08 33.2 19.7 4.4 4 0 0 4 4 4 3 Transcription factor IIA, alpha/beta subunit zf-CCHC_6 PF15288.6 CDJ47519.1 - 0.0015 18.3 1.1 0.0053 16.6 1.1 2.0 1 0 0 1 1 1 1 Zinc knuckle RskA PF10099.9 CDJ47519.1 - 0.007 16.7 8.1 0.007 16.7 8.1 7.5 4 2 2 6 6 6 2 Anti-sigma-K factor rskA zf-CCHC PF00098.23 CDJ47519.1 - 0.0091 16.0 0.4 0.027 14.5 0.4 1.8 1 0 0 1 1 1 1 Zinc knuckle BUD22 PF09073.10 CDJ47519.1 - 0.025 14.0 0.0 0.025 14.0 0.0 4.8 3 2 1 4 4 4 0 BUD22 GDE_N PF12439.8 CDJ47519.1 - 1.4 8.3 5.5 5.3 6.4 5.5 2.0 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal DUF908 PF06012.12 CDJ47520.1 - 0.036 13.5 24.5 0.048 13.1 24.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF726 PF05277.12 CDJ47520.1 - 0.1 11.5 7.8 0.12 11.3 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) O-antigen_lig PF13425.6 CDJ47520.1 - 0.11 11.3 16.3 0.13 11.0 16.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF572 PF04502.13 CDJ47520.1 - 0.13 11.8 31.5 0.17 11.5 31.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4045 PF13254.6 CDJ47520.1 - 0.19 11.3 33.7 0.22 11.2 33.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RR_TM4-6 PF06459.12 CDJ47520.1 - 0.21 11.4 38.9 0.33 10.8 38.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ47520.1 - 0.28 10.0 30.1 0.29 9.9 30.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter MAP7 PF05672.11 CDJ47520.1 - 0.3 10.8 69.4 0.4 10.4 69.4 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family FA_desaturase PF00487.24 CDJ47520.1 - 0.47 10.2 2.3 0.7 9.7 2.3 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Draxin PF15550.6 CDJ47520.1 - 0.79 9.5 24.7 1 9.2 24.7 1.3 1 0 0 1 1 1 0 Draxin Exonuc_VII_L PF02601.15 CDJ47520.1 - 0.81 9.2 48.3 0.97 8.9 48.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GAGA_bind PF06217.12 CDJ47520.1 - 0.81 9.9 35.2 0.86 9.8 35.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RIFIN PF02009.16 CDJ47520.1 - 0.85 9.5 39.8 1.1 9.0 39.8 1.1 1 0 0 1 1 1 0 Rifin PA26 PF04636.13 CDJ47520.1 - 0.85 8.5 29.1 1 8.2 29.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PAT1 PF09770.9 CDJ47520.1 - 0.87 7.8 70.6 1 7.5 70.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.6 CDJ47520.1 - 1.1 9.3 32.3 1.5 8.8 32.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 CDJ47520.1 - 1.1 8.0 51.8 1.6 7.4 51.8 1.3 1 0 0 1 1 1 0 Presenilin DUF1168 PF06658.12 CDJ47520.1 - 1.2 8.9 42.0 2 8.2 42.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CCSAP PF15748.5 CDJ47520.1 - 1.6 8.8 45.8 2.1 8.5 45.8 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MRP-S31 PF15433.6 CDJ47520.1 - 2.2 7.9 39.7 2.8 7.6 39.7 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Miga PF10265.9 CDJ47520.1 - 2.3 7.1 23.8 3.1 6.7 23.8 1.4 1 0 0 1 1 1 0 Mitoguardin CDC27 PF09507.10 CDJ47520.1 - 3.1 7.1 44.3 3.9 6.7 44.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hamartin PF04388.12 CDJ47520.1 - 4 6.0 35.9 4.4 5.8 35.9 1.0 1 0 0 1 1 1 0 Hamartin protein Paramyxo_ncap PF00973.19 CDJ47520.1 - 4.1 6.2 33.9 5 5.9 33.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein AAA_11 PF13086.6 CDJ47520.1 - 5.1 6.8 38.3 6.8 6.4 38.3 1.3 1 0 0 1 1 1 0 AAA domain LAP1C PF05609.12 CDJ47520.1 - 5.4 6.0 40.1 6.2 5.8 40.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 CDJ47520.1 - 5.7 5.1 40.5 7 4.8 40.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 CDJ47521.1 - 2e-09 37.2 0.0 2.8e-05 23.6 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Kinase-like PF14531.6 CDJ47521.1 - 2.1e-06 27.3 9.6 8.1e-05 22.1 1.9 3.3 3 1 0 3 3 3 2 Kinase-like Pkinase_Tyr PF07714.17 CDJ47521.1 - 0.00087 18.6 0.4 0.49 9.6 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase TMEM51 PF15345.6 CDJ47521.1 - 0.0036 17.2 2.9 0.0055 16.6 1.5 2.0 2 0 0 2 2 2 1 Transmembrane protein 51 AI-2E_transport PF01594.16 CDJ47521.1 - 0.0083 15.3 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 AI-2E family transporter Ribosomal_60s PF00428.19 CDJ47521.1 - 0.017 15.7 8.1 0.017 15.7 8.1 4.9 3 1 1 4 4 3 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ47521.1 - 0.059 13.4 29.0 0.19 11.7 14.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CemA PF03040.14 CDJ47521.1 - 0.22 11.5 1.3 0.54 10.2 1.3 1.6 1 0 0 1 1 1 0 CemA family DUF2722 PF10846.8 CDJ47521.1 - 0.25 10.2 12.6 0.016 14.2 5.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ47521.1 - 0.43 11.6 3.4 0.36 11.8 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Nbs1_C PF08599.10 CDJ47521.1 - 0.44 10.7 4.2 4.5 7.5 0.0 3.2 3 0 0 3 3 3 0 DNA damage repair protein Nbs1 DUF4229 PF14012.6 CDJ47521.1 - 0.65 10.1 5.0 3.9 7.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) 60KD_IMP PF02096.20 CDJ47521.1 - 1.9 8.3 5.9 5 7.0 5.9 1.6 1 0 0 1 1 1 0 60Kd inner membrane protein PPI_Ypi1 PF07491.11 CDJ47522.1 - 1.9e-21 75.6 2.2 1.9e-21 75.6 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor Dehydrin PF00257.19 CDJ47522.1 - 0.097 13.2 12.2 0.13 12.8 12.2 1.3 1 1 0 1 1 1 0 Dehydrin DUF3597 PF12200.8 CDJ47522.1 - 1.4 9.4 5.5 2.6 8.6 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Spt20 PF12090.8 CDJ47523.1 - 0.00055 19.6 7.8 0.00055 19.6 7.8 3.0 2 1 1 3 3 3 1 Spt20 family NICE-1 PF15845.5 CDJ47523.1 - 2.1 9.1 13.7 1.5 9.6 5.2 2.7 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family SMYLE_N PF18615.1 CDJ47525.1 - 2.6 7.5 18.8 2.8 7.4 18.8 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain UQ_con PF00179.26 CDJ47526.1 - 4.4e-09 36.1 0.0 4.4e-09 36.1 0.0 3.0 3 1 0 4 4 4 1 Ubiquitin-conjugating enzyme CDC27 PF09507.10 CDJ47526.1 - 0.032 13.6 42.0 0.044 13.2 42.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 CDJ47526.1 - 0.19 11.3 30.5 0.28 10.7 30.5 1.3 1 0 0 1 1 1 0 PPP4R2 Hamartin PF04388.12 CDJ47526.1 - 2.4 6.7 38.5 3.4 6.2 38.5 1.2 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.13 CDJ47526.1 - 2.5 7.8 37.6 3.5 7.3 37.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PAT1 PF09770.9 CDJ47526.1 - 2.7 6.1 69.9 4.3 5.5 69.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WTX PF09422.10 CDJ47526.1 - 2.9 6.9 27.8 3.7 6.5 27.8 1.2 1 0 0 1 1 1 0 WTX protein GREB1 PF15782.5 CDJ47526.1 - 4.1 4.4 40.7 5 4.1 40.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Vac7 PF12751.7 CDJ47526.1 - 7.7 5.8 21.5 12 5.2 21.5 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Spt20 PF12090.8 CDJ47528.1 - 0.022 14.4 20.2 0.024 14.3 20.2 1.1 1 0 0 1 1 1 0 Spt20 family ZapA PF05164.13 CDJ47528.1 - 0.11 13.0 6.0 0.12 12.8 6.0 1.2 1 0 0 1 1 1 0 Cell division protein ZapA RskA PF10099.9 CDJ47528.1 - 0.15 12.3 9.7 0.22 11.8 9.7 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ47528.1 - 0.49 9.1 3.7 0.52 9.0 3.7 1.0 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ47528.1 - 3.8 7.4 20.9 4.2 7.3 20.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EphA2_TM PF14575.6 CDJ47528.1 - 4.9 8.1 5.6 8.9 7.3 5.6 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Proho_convert PF12177.8 CDJ47529.1 - 0.03 14.3 0.2 0.11 12.5 0.2 1.9 1 0 0 1 1 1 0 Prohormone convertase enzyme TMEM51 PF15345.6 CDJ47530.1 - 0.0097 15.8 1.5 0.0097 15.8 1.5 2.3 2 0 0 2 2 2 1 Transmembrane protein 51 EphA2_TM PF14575.6 CDJ47530.1 - 0.014 16.3 1.3 0.084 13.8 0.2 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TFIIA PF03153.13 CDJ47530.1 - 0.54 10.2 39.3 0.3 11.0 1.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ47530.1 - 3.1 8.8 10.9 3.6 8.6 2.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Glu_syn_central PF04898.14 CDJ47531.1 - 0.044 13.3 6.1 0.058 12.9 6.1 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain Asparaginase PF00710.20 CDJ47531.1 - 0.088 12.3 1.7 0.12 11.9 1.7 1.1 1 0 0 1 1 1 0 Asparaginase, N-terminal HemX PF04375.14 CDJ47531.1 - 0.11 11.8 31.0 0.14 11.4 31.0 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Pex24p PF06398.11 CDJ47531.1 - 0.11 11.5 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin CemA PF03040.14 CDJ47531.1 - 1.2 9.1 9.6 1.7 8.6 9.6 1.2 1 0 0 1 1 1 0 CemA family YniB PF14002.6 CDJ47531.1 - 1.5 8.5 6.4 0.26 11.0 2.2 1.8 1 1 1 2 2 2 0 YniB-like protein SR-25 PF10500.9 CDJ47532.1 - 5.3e-06 26.2 30.7 6e-06 26.0 30.7 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ47532.1 - 0.0039 17.9 18.0 0.006 17.3 18.0 1.2 1 0 0 1 1 1 1 Immortalisation up-regulated protein DUF4603 PF15376.6 CDJ47532.1 - 0.65 7.3 24.3 0.7 7.2 24.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CLN3 PF02487.17 CDJ47532.1 - 1 8.3 11.1 1.4 7.9 11.1 1.2 1 0 0 1 1 1 0 CLN3 protein CCDC106 PF15794.5 CDJ47532.1 - 1.3 8.6 27.0 1.8 8.2 27.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDK2AP PF09806.9 CDJ47532.1 - 1.4 8.9 23.6 1.7 8.7 23.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein RR_TM4-6 PF06459.12 CDJ47532.1 - 1.5 8.5 23.2 1.8 8.3 23.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ47532.1 - 1.7 8.6 22.0 2 8.3 22.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A O-antigen_lig PF13425.6 CDJ47532.1 - 1.9 7.2 8.2 2.4 6.9 8.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3381 PF11861.8 CDJ47532.1 - 2.7 7.8 29.6 3.5 7.4 29.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Presenilin PF01080.17 CDJ47532.1 - 4.3 6.0 29.7 5.2 5.7 29.7 1.0 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ47532.1 - 7.4 4.3 19.1 8.2 4.2 19.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SR-25 PF10500.9 CDJ47533.1 - 0.00014 21.6 16.8 0.00014 21.6 16.8 8.7 5 2 2 7 7 7 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ47533.1 - 0.0053 17.1 18.5 0.0053 17.1 18.5 15.2 3 2 5 8 8 8 2 Anti-sigma-K factor rskA YihI PF04220.12 CDJ47535.1 - 0.075 12.7 1.6 0.078 12.7 1.6 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) FAM117 PF15388.6 CDJ47535.1 - 0.076 12.4 1.2 0.077 12.4 1.2 1.2 1 0 0 1 1 1 0 Protein Family FAM117 Chromo PF00385.24 CDJ47536.1 - 4.5e-11 42.5 0.0 9e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LAP1C PF05609.12 CDJ47537.1 - 0.021 14.0 23.5 0.025 13.7 23.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RskA PF10099.9 CDJ47537.1 - 0.031 14.6 29.4 0.026 14.8 6.6 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA B12D PF06522.11 CDJ47537.1 - 0.057 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit ADP_ribosyl_GH PF03747.14 CDJ47537.1 - 0.5 10.0 17.6 0.24 11.1 7.3 2.1 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase Herpes_pp85 PF04637.12 CDJ47537.1 - 0.54 8.6 9.8 0.79 8.1 9.8 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Phage_Gp23 PF10669.9 CDJ47537.1 - 2 8.7 10.2 0.69 10.3 4.8 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF572 PF04502.13 CDJ47537.1 - 2.4 7.7 23.2 3.7 7.1 23.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.13 CDJ47537.1 - 8.9 6.2 23.1 11 5.9 23.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4366 PF14283.6 CDJ47538.1 - 0.0046 17.0 2.0 0.0065 16.5 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Kei1 PF08552.11 CDJ47538.1 - 0.012 15.5 3.3 0.016 15.1 3.3 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4551 PF15087.6 CDJ47538.1 - 0.039 12.8 12.2 0.04 12.8 12.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pex14_N PF04695.13 CDJ47538.1 - 0.098 13.3 22.0 0.12 13.0 22.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.9 CDJ47538.1 - 0.18 12.1 14.5 0.21 11.9 14.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SMYLE_N PF18615.1 CDJ47538.1 - 0.3 10.6 8.3 0.33 10.5 8.3 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain THOC2_N PF16134.5 CDJ47538.1 - 0.31 9.6 7.3 0.33 9.5 7.3 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Rtf2 PF04641.12 CDJ47538.1 - 0.34 10.2 9.5 0.43 9.9 9.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger YihI PF04220.12 CDJ47538.1 - 0.39 10.4 9.3 0.49 10.1 9.3 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) TFIIA PF03153.13 CDJ47538.1 - 0.63 10.0 32.1 0.65 9.9 32.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 CDJ47538.1 - 0.73 9.8 7.4 0.8 9.7 7.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PIP5K PF01504.18 CDJ47538.1 - 1 8.5 5.4 1.2 8.3 5.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Lin-8 PF03353.15 CDJ47538.1 - 1.2 8.6 13.3 1.3 8.5 13.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Gti1_Pac2 PF09729.9 CDJ47538.1 - 1.5 8.9 7.8 1.9 8.5 7.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Velvet PF11754.8 CDJ47538.1 - 1.6 8.6 13.2 1.9 8.4 13.2 1.1 1 0 0 1 1 1 0 Velvet factor Endostatin PF06482.11 CDJ47538.1 - 2 7.8 13.4 2.2 7.7 13.4 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Zip PF02535.22 CDJ47538.1 - 2.2 7.4 6.6 2.5 7.2 6.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 CDJ47538.1 - 2.2 8.0 10.6 2.4 7.9 10.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 CDJ47538.1 - 2.8 7.4 6.4 3.5 7.1 6.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Neur_chan_memb PF02932.16 CDJ47538.1 - 3.3 7.7 11.2 3.4 7.6 11.2 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IER PF05760.12 CDJ47538.1 - 3.4 7.9 16.7 3.4 7.9 16.7 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) Presenilin PF01080.17 CDJ47538.1 - 4.7 5.9 16.1 5.4 5.7 16.1 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ47538.1 - 4.7 6.1 9.0 4.9 6.1 9.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CDJ47538.1 - 5 4.1 11.8 4.9 4.1 11.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ47538.1 - 5.1 5.2 23.6 5.2 5.2 23.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp13 PF08625.11 CDJ47539.1 - 4e-12 46.2 8.4 4e-12 46.2 8.4 2.3 2 2 0 2 2 1 1 Utp13 specific WD40 associated domain DUF3446 PF11928.8 CDJ47539.1 - 0.0056 16.9 2.5 0.0056 16.9 2.5 2.2 2 0 0 2 2 2 1 Early growth response N-terminal domain TCP PF03634.13 CDJ47539.1 - 0.025 15.1 23.2 0.29 11.7 13.6 2.5 2 0 0 2 2 2 0 TCP family transcription factor RR_TM4-6 PF06459.12 CDJ47539.1 - 0.054 13.3 23.7 0.14 12.0 14.8 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2052 PF09747.9 CDJ47539.1 - 0.1 12.7 19.6 0.99 9.5 11.4 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) V_ATPase_I PF01496.19 CDJ47539.1 - 1.1 7.0 23.9 1.2 7.0 13.5 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SR-25 PF10500.9 CDJ47539.1 - 1.3 8.6 30.9 0.17 11.5 8.6 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Caldesmon PF02029.15 CDJ47539.1 - 1.3 7.7 24.7 0.38 9.4 14.8 2.2 2 0 0 2 2 2 0 Caldesmon DUF3807 PF12720.7 CDJ47539.1 - 1.4 9.2 29.3 0.85 9.9 14.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) eIF-3_zeta PF05091.12 CDJ47539.1 - 1.7 7.5 26.6 2.1 7.2 4.6 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TRAP_alpha PF03896.16 CDJ47539.1 - 1.8 7.7 9.0 4.3 6.5 2.6 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Afi1 PF07792.12 CDJ47539.1 - 2.2 8.8 19.5 3.7 8.0 9.2 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Spore_coat_CotO PF14153.6 CDJ47539.1 - 3.3 7.6 29.2 1.8 8.5 3.3 2.6 2 0 0 2 2 2 0 Spore coat protein CotO CCDC53 PF10152.9 CDJ47539.1 - 5.8 7.3 25.7 2.5 8.5 3.4 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex PPL5 PF18168.1 CDJ47539.1 - 6.6 5.9 15.1 9.7 5.4 0.7 2.3 2 0 0 2 2 2 0 Prim-pol family 5 Zip PF02535.22 CDJ47539.1 - 8.1 5.6 11.2 7.3 5.7 4.4 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter MFS_1 PF07690.16 CDJ47540.1 - 2.1e-07 30.2 2.4 2.1e-07 30.2 2.4 3.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2448 PF10476.9 CDJ47541.1 - 0.015 15.2 0.4 0.015 15.2 0.4 3.3 2 1 1 4 4 4 0 Protein of unknown function C-terminus (DUF2448) ETRAMP PF09716.10 CDJ47541.1 - 0.088 12.9 0.0 0.088 12.9 0.0 4.1 6 0 0 6 6 6 0 Malarial early transcribed membrane protein (ETRAMP) RskA PF10099.9 CDJ47541.1 - 0.29 11.4 0.0 0.29 11.4 0.0 4.3 2 1 2 4 4 4 0 Anti-sigma-K factor rskA SprA-related PF12118.8 CDJ47542.1 - 9.1e-05 21.8 58.6 9.1e-05 21.8 58.6 11.4 7 2 3 11 11 11 3 SprA-related family PBP1_TM PF14812.6 CDJ47543.1 - 1.5 9.2 5.7 52 4.3 0.2 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF5320 PF17253.2 CDJ47544.1 - 0.016 16.3 2.6 0.016 16.3 2.6 2.0 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Corona_nucleoca PF00937.18 CDJ47544.1 - 1.5 7.8 8.8 2.2 7.2 8.8 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SR-25 PF10500.9 CDJ47545.1 - 7.8e-05 22.4 33.8 7.8e-05 22.4 33.8 2.3 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein GGDEF PF00990.21 CDJ47545.1 - 0.0026 17.5 4.6 0.0026 17.5 4.6 2.8 2 1 1 3 3 3 1 Diguanylate cyclase, GGDEF domain PI3K_1B_p101 PF10486.9 CDJ47545.1 - 0.11 10.2 24.5 0.15 9.8 24.5 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FHA PF00498.26 CDJ47546.1 - 2.8e-11 43.6 0.0 1.1e-10 41.7 0.0 2.1 2 0 0 2 2 2 1 FHA domain Apt1 PF10351.9 CDJ47546.1 - 0.00022 20.3 6.3 0.00023 20.1 6.3 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain CDC45 PF02724.14 CDJ47546.1 - 0.00026 19.5 15.7 0.00032 19.2 15.7 1.1 1 0 0 1 1 1 1 CDC45-like protein RskA PF10099.9 CDJ47546.1 - 0.0025 18.1 17.3 0.0025 18.1 17.3 5.0 1 1 3 4 4 4 1 Anti-sigma-K factor rskA Yop-YscD_cpl PF16697.5 CDJ47546.1 - 0.0049 17.2 0.0 0.0049 17.2 0.0 2.4 3 1 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain GREB1 PF15782.5 CDJ47546.1 - 3.4 4.7 25.2 4.2 4.4 25.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sin_N PF04801.13 CDJ47546.1 - 3.4 6.8 43.7 1.1 8.4 40.5 1.7 2 0 0 2 2 2 0 Sin-like protein conserved region DUF966 PF06136.13 CDJ47546.1 - 4.1 7.0 19.8 5.8 6.5 19.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CCSAP PF15748.5 CDJ47546.1 - 4.8 7.3 35.6 10 6.2 35.6 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PAT1 PF09770.9 CDJ47546.1 - 7.3 4.7 51.0 0.24 9.6 44.8 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 IF-2B PF01008.17 CDJ47547.1 - 2.9e-09 36.6 1.7 7.5e-09 35.2 1.7 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family RskA PF10099.9 CDJ47547.1 - 0.75 10.1 14.4 2.8 8.2 13.8 2.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF4551 PF15087.6 CDJ47547.1 - 5 5.8 15.4 6.3 5.5 15.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Activator_LAG-3 PF11498.8 CDJ47548.1 - 3.4 6.5 43.0 0.85 8.5 20.2 2.8 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SR-25 PF10500.9 CDJ47548.1 - 9 5.8 25.4 0.022 14.4 11.6 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 CDJ47549.1 - 0.0042 16.7 18.1 0.0051 16.4 18.1 1.0 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist SpoIIP PF07454.11 CDJ47549.1 - 0.0057 16.2 7.5 0.0057 16.2 7.5 1.0 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) CobT PF06213.12 CDJ47549.1 - 0.0057 16.1 12.7 0.0057 16.1 12.7 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT UPF0560 PF10577.9 CDJ47549.1 - 0.014 13.9 18.5 0.014 13.9 18.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIA PF03153.13 CDJ47549.1 - 0.019 15.0 32.2 0.021 14.8 32.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.13 CDJ47549.1 - 0.052 13.4 9.7 0.055 13.3 9.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain EPL1 PF10513.9 CDJ47549.1 - 0.07 13.5 10.4 0.088 13.2 10.4 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like SLC12 PF03522.15 CDJ47549.1 - 0.073 12.1 9.7 0.073 12.1 9.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ47549.1 - 0.075 11.8 13.8 0.075 11.8 13.8 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 CDJ47549.1 - 0.09 11.6 7.0 0.084 11.7 7.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ47549.1 - 0.17 10.2 20.7 0.17 10.2 20.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CSG2 PF16965.5 CDJ47549.1 - 0.21 10.5 7.6 0.26 10.2 7.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator CLN3 PF02487.17 CDJ47549.1 - 0.21 10.6 10.9 0.26 10.3 10.9 1.1 1 0 0 1 1 1 0 CLN3 protein PepSY_TM PF03929.16 CDJ47549.1 - 0.21 11.2 2.6 0.22 11.2 2.6 1.1 1 0 0 1 1 1 0 PepSY-associated TM region DUF1645 PF07816.11 CDJ47549.1 - 0.25 11.9 18.7 0.53 10.8 18.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) DUF4366 PF14283.6 CDJ47549.1 - 0.31 11.1 4.0 0.41 10.7 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Exonuc_VII_L PF02601.15 CDJ47549.1 - 0.34 10.4 11.9 0.33 10.5 11.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RIC3 PF15361.6 CDJ47549.1 - 0.43 11.0 8.8 0.56 10.6 8.8 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4638 PF15472.6 CDJ47549.1 - 0.47 10.1 10.2 0.49 10.1 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) CDC45 PF02724.14 CDJ47549.1 - 0.56 8.4 10.4 0.55 8.5 10.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 CDJ47549.1 - 0.72 7.9 13.7 0.86 7.6 13.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Connexin PF00029.19 CDJ47549.1 - 1.1 8.9 11.2 1.5 8.6 11.2 1.1 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.19 CDJ47549.1 - 1.2 7.0 16.2 1.4 6.7 16.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Otopetrin PF03189.13 CDJ47549.1 - 1.3 7.8 9.3 1.4 7.6 9.3 1.0 1 0 0 1 1 1 0 Otopetrin Tim54 PF11711.8 CDJ47549.1 - 1.6 7.5 12.2 1.9 7.2 12.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4407 PF14362.6 CDJ47549.1 - 1.7 8.0 14.5 1.9 7.8 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Kei1 PF08552.11 CDJ47549.1 - 1.7 8.5 7.0 1.8 8.4 7.0 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Totivirus_coat PF05518.11 CDJ47549.1 - 1.8 6.5 5.7 2.2 6.3 5.7 1.0 1 0 0 1 1 1 0 Totivirus coat protein Peptidase_S64 PF08192.11 CDJ47549.1 - 2 6.8 18.1 2.2 6.7 18.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 CPSF100_C PF13299.6 CDJ47549.1 - 2 8.6 11.8 2.7 8.1 11.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hid1 PF12722.7 CDJ47549.1 - 2.1 6.4 12.5 2.1 6.4 12.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 CDJ47549.1 - 2.2 6.7 17.7 2.9 6.3 17.7 1.2 1 0 0 1 1 1 0 Macoilin family Paramyxo_ncap PF00973.19 CDJ47549.1 - 2.3 7.0 8.1 2.4 6.9 8.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Folate_carrier PF01770.18 CDJ47549.1 - 2.4 6.8 7.1 2.8 6.6 7.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier SPX PF03105.19 CDJ47549.1 - 2.5 7.9 16.8 2.8 7.8 16.8 1.0 1 0 0 1 1 1 0 SPX domain BORG_CEP PF14957.6 CDJ47549.1 - 2.6 9.2 13.4 3.7 8.7 13.4 1.3 1 0 0 1 1 1 0 Cdc42 effector Miga PF10265.9 CDJ47549.1 - 3.8 6.4 17.1 4.2 6.2 17.1 1.0 1 0 0 1 1 1 0 Mitoguardin Zip PF02535.22 CDJ47549.1 - 4 6.6 8.1 4.3 6.5 8.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Paf1 PF03985.13 CDJ47549.1 - 4.2 6.3 16.5 5.5 5.9 16.5 1.1 1 0 0 1 1 1 0 Paf1 EMC3_TMCO1 PF01956.16 CDJ47549.1 - 5.1 6.8 9.5 5.6 6.7 9.5 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RR_TM4-6 PF06459.12 CDJ47549.1 - 5.3 6.8 15.9 7.1 6.4 15.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Membralin PF09746.9 CDJ47549.1 - 5.4 6.0 10.3 6.7 5.6 10.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4746 PF15928.5 CDJ47549.1 - 5.5 6.3 11.7 6.9 6.0 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SID-1_RNA_chan PF13965.6 CDJ47549.1 - 5.6 5.3 7.0 6.4 5.1 7.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PIP5K PF01504.18 CDJ47549.1 - 5.7 6.1 13.1 7.8 5.6 13.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_U57 PF05582.12 CDJ47549.1 - 6 6.0 12.9 7.6 5.7 12.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Sec62 PF03839.16 CDJ47549.1 - 6.6 6.2 12.0 8.4 5.8 12.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 NARP1 PF12569.8 CDJ47549.1 - 7.2 5.4 14.5 8.9 5.1 14.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GREB1 PF15782.5 CDJ47549.1 - 8.2 3.4 22.6 9 3.3 22.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FliP PF00813.20 CDJ47549.1 - 9.3 6.1 7.6 11 5.8 7.6 1.1 1 0 0 1 1 1 0 FliP family Exonuc_VII_L PF02601.15 CDJ47550.1 - 0.00084 19.0 0.3 0.00084 19.0 0.3 12.8 5 3 4 10 10 10 1 Exonuclease VII, large subunit FAM176 PF14851.6 CDJ47550.1 - 0.021 14.5 0.1 0.021 14.5 0.1 15.1 9 4 4 13 13 13 0 FAM176 family AAA_23 PF13476.6 CDJ47552.1 - 0.22 12.0 23.3 0.085 13.3 0.7 2.4 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.19 CDJ47552.1 - 0.42 8.5 23.2 0.033 12.1 5.5 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CNDH2_C PF16858.5 CDJ47552.1 - 0.79 9.5 20.8 1.7 8.5 5.9 2.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term PIEZO PF15917.5 CDJ47552.1 - 1.1 8.6 24.5 0.93 8.9 8.7 2.7 2 0 0 2 2 2 0 Piezo Connexin PF00029.19 CDJ47552.1 - 1.4 8.6 13.5 1.6 8.4 1.9 2.5 2 0 0 2 2 2 0 Connexin DUF898 PF05987.13 CDJ47552.1 - 2 7.4 14.7 66 2.4 11.5 3.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.9 CDJ47552.1 - 2.7 6.7 3.9 3.9 6.1 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) MAP7 PF05672.11 CDJ47552.1 - 3.4 7.3 43.4 4.6 6.9 14.1 2.6 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family eIF-3_zeta PF05091.12 CDJ47552.1 - 9.1 5.1 30.0 1.9 7.4 9.4 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TRM13 PF05206.14 CDJ47552.1 - 9.5 5.6 15.8 1.9 7.9 0.5 2.5 2 0 0 2 2 2 0 Methyltransferase TRM13 MRP-S27 PF10037.9 CDJ47553.1 - 0.1 11.5 17.0 0.11 11.3 17.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Activator_LAG-3 PF11498.8 CDJ47553.1 - 0.18 10.7 82.4 0.33 9.9 82.4 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CDK5_activator PF03261.15 CDJ47553.1 - 6.7 6.1 17.7 9 5.7 17.7 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PAT1 PF09770.9 CDJ47553.1 - 8.2 4.6 45.7 10 4.3 45.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PQQ_3 PF13570.6 CDJ47554.1 - 0.00026 21.4 0.0 0.067 13.7 0.1 3.5 2 0 0 2 2 2 1 PQQ-like domain SUIM_assoc PF16619.5 CDJ47554.1 - 0.0038 17.3 2.2 0.0038 17.3 2.2 9.0 4 2 3 7 7 7 2 Unstructured region C-term to UIM in Ataxin3 Exo_endo_phos PF03372.23 CDJ47554.1 - 0.031 13.8 0.0 0.031 13.8 0.0 2.6 4 0 0 4 4 4 0 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 CDJ47554.1 - 0.15 13.0 0.1 6.3 7.8 0.0 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC1 PF12859.7 CDJ47555.1 - 0.13 12.8 2.7 0.18 12.4 2.7 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 RSRP PF17069.5 CDJ47555.1 - 0.92 9.0 16.2 1.2 8.7 16.2 1.0 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 DSPc PF00782.20 CDJ47556.1 - 1.1e-05 25.3 0.2 1.1e-05 25.3 0.2 2.9 3 0 0 3 3 1 1 Dual specificity phosphatase, catalytic domain DUF2722 PF10846.8 CDJ47556.1 - 0.00021 20.4 3.7 0.00021 20.4 3.7 8.8 6 2 3 9 9 4 2 Protein of unknown function (DUF2722) Utp14 PF04615.13 CDJ47556.1 - 0.00022 20.0 29.3 0.00022 20.0 29.3 4.9 3 3 2 5 5 2 2 Utp14 protein DUF2828 PF11443.8 CDJ47556.1 - 0.00086 17.5 11.9 0.00086 17.5 11.9 6.0 5 1 0 5 5 4 1 Domain of unknown function (DUF2828) Spt20 PF12090.8 CDJ47556.1 - 0.0012 18.5 8.6 0.0012 18.5 8.6 9.4 6 2 3 9 9 5 2 Spt20 family Pex14_N PF04695.13 CDJ47556.1 - 0.0014 19.3 7.3 0.0014 19.3 7.3 9.9 6 2 3 9 9 5 2 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 CDJ47556.1 - 0.002 18.0 24.7 0.002 18.0 24.7 6.4 5 1 1 6 6 4 3 Ryanodine Receptor TM 4-6 CAC1F_C PF16885.5 CDJ47556.1 - 0.0043 16.8 8.0 0.0043 16.8 8.0 5.8 4 2 0 4 4 2 2 Voltage-gated calcium channel subunit alpha, C-term Y_phosphatase3 PF13350.6 CDJ47556.1 - 0.026 14.5 0.1 0.026 14.5 0.1 4.4 5 0 0 5 5 4 0 Tyrosine phosphatase family SurA_N_2 PF13623.6 CDJ47556.1 - 0.41 10.5 0.0 0.41 10.5 0.0 8.3 7 1 1 8 8 5 0 SurA N-terminal domain TFIIA PF03153.13 CDJ47556.1 - 0.79 9.6 205.6 0.33 10.9 15.2 5.6 5 1 0 5 5 4 0 Transcription factor IIA, alpha/beta subunit EF-hand_7 PF13499.6 CDJ47558.1 - 8.9e-10 38.9 4.8 8.9e-10 38.9 4.8 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ47558.1 - 3.7e-09 35.8 3.5 0.00051 19.8 0.4 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDJ47558.1 - 6.6e-09 34.7 7.5 7.7e-05 22.0 1.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ47558.1 - 6.2e-08 32.4 1.8 1.7e-07 31.0 1.8 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ47558.1 - 8.9e-07 28.1 7.7 0.0079 15.7 0.7 2.6 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 CDJ47558.1 - 0.57 10.5 15.0 4.3 7.7 15.0 2.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region RRN3 PF05327.11 CDJ47558.1 - 1.2 7.5 8.3 1.6 7.2 8.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 U3_assoc_6 PF08640.11 CDJ47559.1 - 1.1e-11 44.6 4.3 1.1e-11 44.6 4.3 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 SR-25 PF10500.9 CDJ47559.1 - 0.00051 19.7 4.7 0.00051 19.7 4.7 10.9 7 3 1 10 10 10 6 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ47559.1 - 0.0053 17.0 9.0 0.0053 17.0 9.0 15.4 13 3 1 14 14 14 3 Domain of unknown function (DUF755) RskA PF10099.9 CDJ47559.1 - 0.01 16.2 0.2 0.01 16.2 0.2 9.9 3 1 5 9 9 9 0 Anti-sigma-K factor rskA DNA_pol_E_B PF04042.16 CDJ47559.1 - 0.085 12.2 2.5 0.15 11.4 0.1 2.7 2 0 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B FAM104 PF15434.6 CDJ47559.1 - 0.77 10.4 0.0 0.65 10.6 3.3 10.6 7 2 2 10 10 10 0 Family 104 BUD22 PF09073.10 CDJ47559.1 - 4.5 6.5 88.5 0.026 13.9 11.4 6.6 2 1 2 5 5 5 0 BUD22 Cwf_Cwc_15 PF04889.12 CDJ47560.1 - 0.00046 20.0 25.1 0.0007 19.4 25.1 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3446 PF11928.8 CDJ47560.1 - 0.011 16.0 17.4 0.016 15.5 1.0 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Pox_Ag35 PF03286.14 CDJ47560.1 - 0.03 14.1 19.7 0.038 13.8 19.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Shadoo PF14999.6 CDJ47560.1 - 0.069 13.3 1.8 0.11 12.6 1.8 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective SR-25 PF10500.9 CDJ47560.1 - 0.086 12.4 39.6 0.17 11.5 14.8 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein PPP4R2 PF09184.11 CDJ47560.1 - 0.2 11.2 24.0 0.24 11.0 24.0 1.1 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 CDJ47560.1 - 0.46 9.8 31.2 0.51 9.6 31.2 1.1 1 0 0 1 1 1 0 BUD22 DUF2254 PF10011.9 CDJ47560.1 - 0.7 8.7 3.3 1.8 7.3 3.3 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF755 PF05501.11 CDJ47560.1 - 0.85 9.9 31.1 0.11 12.8 7.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Nop14 PF04147.12 CDJ47560.1 - 1.4 7.0 26.7 1.5 6.9 26.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 CDJ47560.1 - 1.6 7.6 12.9 2.1 7.2 12.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Med13_C PF06333.12 CDJ47560.1 - 2.7 7.2 7.1 3.2 6.9 7.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Macoilin PF09726.9 CDJ47560.1 - 3.6 6.0 17.0 3.9 5.9 17.0 1.0 1 0 0 1 1 1 0 Macoilin family PNISR PF15996.5 CDJ47560.1 - 3.8 7.7 24.3 4.8 7.4 24.3 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Na_trans_assoc PF06512.13 CDJ47560.1 - 4.2 7.6 20.8 5.2 7.3 20.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated ORC6 PF05460.13 CDJ47560.1 - 4.5 6.5 16.9 5 6.3 16.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Myc_N PF01056.18 CDJ47560.1 - 4.5 7.1 28.4 0.031 14.2 13.6 2.0 1 1 1 2 2 2 0 Myc amino-terminal region Neur_chan_memb PF02932.16 CDJ47560.1 - 7.5 6.5 5.3 8.7 6.3 5.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.6 CDJ47560.1 - 8.1 5.1 14.4 8.4 5.1 14.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3138 PF11336.8 CDJ47561.1 - 6 5.4 21.1 8.9 4.8 21.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spt20 PF12090.8 CDJ47561.1 - 6.3 6.3 26.5 2.6 7.6 6.1 2.2 2 0 0 2 2 2 0 Spt20 family RskA PF10099.9 CDJ47561.1 - 6.4 7.0 44.0 4 7.7 19.9 2.6 1 1 1 2 2 2 0 Anti-sigma-K factor rskA T2SSC PF11356.8 CDJ47562.1 - 0.039 13.9 0.8 0.049 13.5 0.8 1.1 1 0 0 1 1 1 0 Type II secretion system protein C Apt1 PF10351.9 CDJ47564.1 - 0.071 12.0 1.3 0.062 12.1 1.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC106 PF15794.5 CDJ47564.1 - 0.71 9.5 6.5 1 9.0 6.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SOG2 PF10428.9 CDJ47564.1 - 0.92 8.6 14.3 1 8.5 14.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Syntaphilin PF15290.6 CDJ47564.1 - 1.5 8.4 16.5 2.6 7.6 16.5 1.4 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Ribosomal_60s PF00428.19 CDJ47564.1 - 1.6 9.4 41.6 1.5 9.5 14.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein MAP65_ASE1 PF03999.12 CDJ47564.1 - 5 5.7 7.3 4.7 5.8 7.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) HemX PF04375.14 CDJ47565.1 - 0.052 12.8 33.4 0.065 12.5 33.4 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase RR_TM4-6 PF06459.12 CDJ47565.1 - 0.08 12.8 20.0 0.088 12.6 20.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4192 PF13830.6 CDJ47565.1 - 0.11 12.5 13.5 0.11 12.5 13.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CAC1F_C PF16885.5 CDJ47565.1 - 0.3 10.7 13.1 0.32 10.6 13.1 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term AF-4 PF05110.13 CDJ47565.1 - 0.46 8.5 30.0 0.46 8.5 30.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RskA PF10099.9 CDJ47565.1 - 0.5 10.7 22.3 1.2 9.3 22.3 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SMN PF06003.12 CDJ47565.1 - 0.5 9.6 5.3 0.63 9.2 5.3 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DDHD PF02862.17 CDJ47565.1 - 0.55 10.4 15.4 0.69 10.0 15.4 1.2 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ47565.1 - 0.65 8.9 23.8 0.72 8.8 23.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) IHABP4_N PF16174.5 CDJ47565.1 - 0.69 10.5 28.6 0.89 10.1 28.6 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4746 PF15928.5 CDJ47565.1 - 0.74 9.2 13.9 0.89 8.9 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Macoilin PF09726.9 CDJ47565.1 - 0.75 8.3 20.9 0.87 8.1 20.9 1.1 1 0 0 1 1 1 0 Macoilin family Serinc PF03348.15 CDJ47565.1 - 1 8.2 8.9 1.1 8.1 8.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hydin_ADK PF17213.3 CDJ47565.1 - 1.3 9.2 22.5 1.8 8.8 22.5 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain HCO3_cotransp PF00955.21 CDJ47565.1 - 1.5 7.6 7.3 1.6 7.5 7.3 1.0 1 0 0 1 1 1 0 HCO3- transporter family SID-1_RNA_chan PF13965.6 CDJ47565.1 - 1.5 7.2 7.5 1.7 7.0 7.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BORG_CEP PF14957.6 CDJ47565.1 - 1.7 9.8 13.5 2.3 9.4 13.5 1.3 1 0 0 1 1 1 0 Cdc42 effector GREB1 PF15782.5 CDJ47565.1 - 1.8 5.6 20.5 2.1 5.3 20.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Gti1_Pac2 PF09729.9 CDJ47565.1 - 2 8.5 17.0 2.6 8.1 17.0 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family NPR3 PF03666.13 CDJ47565.1 - 2.3 6.9 18.2 2.5 6.8 18.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 CDJ47565.1 - 2.6 6.9 21.1 2.9 6.8 21.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 TFIIA PF03153.13 CDJ47565.1 - 2.7 7.9 48.4 3.8 7.4 48.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4045 PF13254.6 CDJ47565.1 - 2.9 7.5 20.0 3 7.4 20.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM60A PF15396.6 CDJ47565.1 - 2.9 7.8 17.4 3.4 7.6 17.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Cellulose_synt PF03552.14 CDJ47565.1 - 3.2 6.1 5.0 3.4 6.0 5.0 1.1 1 0 0 1 1 1 0 Cellulose synthase CDK5_activator PF03261.15 CDJ47565.1 - 3.3 7.2 19.2 3.6 7.0 19.2 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Lin-8 PF03353.15 CDJ47565.1 - 3.3 7.2 23.1 3.8 7.0 23.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RIFIN PF02009.16 CDJ47565.1 - 3.4 7.5 11.9 4.6 7.0 11.9 1.2 1 0 0 1 1 1 0 Rifin PIP5K PF01504.18 CDJ47565.1 - 3.6 6.7 15.2 4.3 6.5 15.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Presenilin PF01080.17 CDJ47565.1 - 3.7 6.2 29.2 4.4 6.0 29.2 1.0 1 0 0 1 1 1 0 Presenilin Helicase_RecD PF05127.14 CDJ47565.1 - 4 7.3 10.9 5.8 6.7 10.9 1.2 1 0 0 1 1 1 0 Helicase MCM_bind PF09739.9 CDJ47565.1 - 4.2 5.7 18.8 4.9 5.5 18.8 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PNISR PF15996.5 CDJ47565.1 - 4.2 7.6 21.6 5.1 7.3 21.6 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Endostatin PF06482.11 CDJ47565.1 - 4.6 6.6 25.3 5.4 6.4 25.3 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF1387 PF07139.11 CDJ47565.1 - 4.9 6.8 21.1 6 6.5 21.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Miga PF10265.9 CDJ47565.1 - 5.1 5.9 11.3 6.2 5.7 11.3 1.0 1 0 0 1 1 1 0 Mitoguardin Asp-B-Hydro_N PF05279.11 CDJ47565.1 - 5.4 7.0 14.9 6 6.9 14.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ctr PF04145.15 CDJ47565.1 - 5.8 7.5 13.6 7.4 7.2 13.6 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Neur_chan_memb PF02932.16 CDJ47565.1 - 6.1 6.8 19.6 7.2 6.6 19.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 CDJ47565.1 - 6.1 5.5 18.4 7.4 5.2 18.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Band_3_cyto PF07565.13 CDJ47565.1 - 7.1 6.3 21.2 9 6.0 21.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Connexin PF00029.19 CDJ47565.1 - 7.3 6.3 17.5 11 5.7 17.5 1.4 1 0 0 1 1 1 0 Connexin ALMT PF11744.8 CDJ47565.1 - 7.4 5.3 18.4 8.7 5.0 18.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_S49_N PF08496.10 CDJ47565.1 - 7.9 6.5 18.6 10 6.1 18.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.14 CDJ47565.1 - 9.4 4.4 18.6 11 4.1 18.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.19 CDJ47566.1 - 5.2 7.7 30.9 0.78 10.4 7.4 4.0 4 0 0 4 4 4 0 60s Acidic ribosomal protein RRM_1 PF00076.22 CDJ47567.1 - 1.9e-07 30.8 0.0 0.82 9.5 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S9 PF00326.21 CDJ47568.1 - 4e-07 29.7 18.5 0.00052 19.6 1.1 5.2 5 0 0 5 5 5 2 Prolyl oligopeptidase family Spt20 PF12090.8 CDJ47568.1 - 0.0011 18.6 4.4 0.0011 18.6 4.4 10.9 7 4 2 9 9 9 2 Spt20 family DDE_Tnp_IS1595 PF12762.7 CDJ47568.1 - 0.16 12.0 0.3 1.5 8.8 0.1 2.7 3 0 0 3 3 3 0 ISXO2-like transposase domain Diphthamide_syn PF01866.17 CDJ47569.1 - 9.9e-05 21.9 0.0 0.071 12.5 0.0 2.6 2 0 0 2 2 2 2 Putative diphthamide synthesis protein DCP2 PF05026.13 CDJ47571.1 - 8.1e-12 45.3 0.6 8.1e-12 45.3 0.6 2.1 2 0 0 2 2 2 1 Dcp2, box A domain LsmAD PF06741.13 CDJ47571.1 - 0.0014 19.2 2.1 0.0014 19.2 2.1 5.3 6 1 0 6 6 6 1 LsmAD domain NUDIX PF00293.28 CDJ47571.1 - 0.0018 18.3 0.0 0.0058 16.7 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain Prefoldin_2 PF01920.20 CDJ47572.1 - 4.5e-14 52.3 4.1 5.2e-14 52.1 4.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.10 CDJ47572.1 - 0.018 15.2 3.3 0.76 10.0 0.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Dynactin_p22 PF07426.11 CDJ47572.1 - 0.044 13.6 4.5 0.17 11.7 3.4 1.9 2 0 0 2 2 2 0 Dynactin subunit p22 MitMem_reg PF13012.6 CDJ47572.1 - 0.045 14.2 1.8 0.084 13.3 1.8 1.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function FlaC_arch PF05377.11 CDJ47572.1 - 0.046 14.1 2.3 1.8 9.0 0.0 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Tugs PF17840.1 CDJ47572.1 - 0.062 13.5 0.7 0.062 13.5 0.7 2.0 2 1 0 2 2 2 0 Tethering Ubl4a to BAGS domain YabA PF06156.13 CDJ47572.1 - 0.066 13.9 3.5 0.46 11.2 1.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA AAA_19 PF13245.6 CDJ47572.1 - 0.088 13.1 0.1 0.097 13.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain DUF4618 PF15397.6 CDJ47572.1 - 0.16 11.4 8.4 3.8 6.9 0.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) Silic_transp PF03842.13 CDJ47572.1 - 0.21 9.8 0.6 0.24 9.6 0.6 1.0 1 0 0 1 1 1 0 Silicon transporter Swi5 PF07061.11 CDJ47572.1 - 0.28 11.3 5.5 4.4 7.5 0.0 2.5 2 1 0 2 2 2 0 Swi5 Vir_act_alpha_C PF10400.9 CDJ47572.1 - 0.72 10.6 4.7 0.91 10.2 2.9 1.9 1 1 1 2 2 2 0 Virulence activator alpha C-term FtsJ PF01728.19 CDJ47573.1 - 1e-17 64.8 0.2 3.3e-16 59.9 0.0 2.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CDJ47573.1 - 1.3e-13 51.1 17.2 1.3e-13 51.1 17.2 4.2 3 1 1 4 4 4 2 Domain of unknown function (DUF3381) RskA PF10099.9 CDJ47573.1 - 0.00067 20.0 7.8 0.00067 20.0 7.8 3.4 2 1 1 3 3 3 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ47574.1 - 0.00015 20.9 2.8 0.00015 20.9 2.8 4.3 3 1 1 4 4 3 1 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ47574.1 - 0.0025 18.2 6.7 0.0025 18.2 6.7 3.4 2 1 0 2 2 1 1 Enhancer of polycomb-like D123 PF07065.14 CDJ47574.1 - 0.0052 16.0 0.4 0.098 11.8 0.1 4.7 3 2 0 4 4 2 2 D123 tRNA_NucTran2_2 PF13735.6 CDJ47574.1 - 0.022 14.7 3.2 0.022 14.7 3.2 4.2 3 1 0 3 3 2 0 tRNA nucleotidyltransferase domain 2 putative PIP5K PF01504.18 CDJ47574.1 - 0.083 12.1 19.3 0.14 11.3 7.4 2.3 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase CCSAP PF15748.5 CDJ47574.1 - 0.47 10.6 46.6 0.56 10.3 14.8 3.4 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated CLN3 PF02487.17 CDJ47574.1 - 0.75 8.8 20.3 0.25 10.3 7.6 2.3 2 0 0 2 2 2 0 CLN3 protein SLC12 PF03522.15 CDJ47574.1 - 1.4 7.9 27.8 0.16 10.9 10.6 2.1 2 0 0 2 2 2 0 Solute carrier family 12 CAF1 PF04857.20 CDJ47574.1 - 2.3 7.3 15.8 0.93 8.6 4.6 2.4 2 0 0 2 2 2 0 CAF1 family ribonuclease DUF913 PF06025.12 CDJ47574.1 - 2.8 6.8 20.0 0.03 13.3 3.7 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) FAM60A PF15396.6 CDJ47574.1 - 3.4 7.6 20.8 1.3 8.9 8.3 2.5 2 0 0 2 2 2 0 Protein Family FAM60A TCP PF03634.13 CDJ47574.1 - 3.8 8.1 34.9 0.19 12.3 9.7 3.3 3 0 0 3 3 3 0 TCP family transcription factor DUF2828 PF11443.8 CDJ47574.1 - 4.4 5.3 26.3 0.84 7.6 10.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ47574.1 - 5.8 5.6 41.0 0.035 12.9 13.4 2.8 3 0 0 3 3 3 0 Presenilin Zip PF02535.22 CDJ47574.1 - 8.7 5.4 8.5 1 8.5 1.0 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter SUIM_assoc PF16619.5 CDJ47575.1 - 0.045 13.8 8.5 0.045 13.8 8.5 3.1 2 1 0 2 2 1 0 Unstructured region C-term to UIM in Ataxin3 INSIG PF07281.12 CDJ47575.1 - 0.058 13.0 3.1 0.061 13.0 3.1 1.0 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) Erv26 PF04148.13 CDJ47575.1 - 0.097 12.5 0.8 0.13 12.1 0.8 1.2 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 GN3L_Grn1 PF08701.11 CDJ47575.1 - 0.35 11.0 14.3 0.2 11.8 5.5 2.0 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase DUF2681 PF10883.8 CDJ47575.1 - 0.56 10.6 27.2 1 9.8 12.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Conotoxin PF02950.17 CDJ47575.1 - 0.87 10.7 8.3 3.4 8.8 2.1 2.1 2 0 0 2 2 2 0 Conotoxin Presenilin PF01080.17 CDJ47575.1 - 1.1 8.0 9.2 1.3 7.7 9.2 1.1 1 0 0 1 1 1 0 Presenilin 7tm_2 PF00002.24 CDJ47575.1 - 1.1 8.5 2.8 1.3 8.2 1.9 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (Secretin family) DUF2140 PF09911.9 CDJ47575.1 - 1.3 8.5 9.2 0.13 11.8 0.6 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Tom22 PF04281.13 CDJ47575.1 - 5 6.9 17.6 0.03 14.1 5.1 2.2 1 1 1 2 2 2 0 Mitochondrial import receptor subunit Tom22 CrgA PF06781.12 CDJ47575.1 - 5.8 7.0 5.7 4.6 7.4 0.0 2.0 1 1 1 2 2 2 0 Cell division protein CrgA Jiraiya PF15038.6 CDJ47575.1 - 6.6 6.1 5.6 1.1 8.7 0.4 1.9 2 0 0 2 2 2 0 Jiraiya CNDH2_N PF06278.11 CDJ47575.1 - 8.5 6.6 14.2 9.8 6.4 6.6 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal RRP14 PF15459.6 CDJ47575.1 - 8.9 7.0 14.5 0.5 11.0 3.7 2.1 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Helicase_C PF00271.31 CDJ47576.1 - 1.8e-07 31.4 0.0 3.6e-06 27.3 0.0 3.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 CDJ47576.1 - 6e-06 26.5 5.2 1.9e-05 24.9 3.5 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ47576.1 - 1.4e-05 25.0 7.1 1.8e-05 24.6 4.4 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDJ47576.1 - 8.3e-05 22.4 3.9 8.3e-05 22.4 3.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ47576.1 - 0.00054 19.6 4.8 0.0014 18.3 0.6 3.1 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CDJ47576.1 - 0.00062 19.9 1.1 0.00062 19.9 1.1 3.0 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CDJ47576.1 - 0.0033 17.2 3.2 0.0033 17.2 3.2 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CDJ47576.1 - 0.0042 16.9 2.0 0.0042 16.9 2.0 2.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 CDJ47576.1 - 0.02 14.9 10.5 0.19 11.7 10.2 2.9 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_1 PF14446.6 CDJ47576.1 - 0.46 10.4 5.9 0.57 10.2 4.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 CDJ47576.1 - 1.8 8.5 12.4 3.4 7.6 7.6 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DUF4050 PF13259.6 CDJ47577.1 - 0.012 15.9 15.7 0.012 15.9 15.7 5.5 3 2 0 4 4 4 0 Protein of unknown function (DUF4050) TPR_1 PF00515.28 CDJ47577.1 - 0.067 13.0 14.4 1.8 8.5 2.9 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ47577.1 - 8.1 6.9 9.3 32 5.1 1.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 CDJ47580.1 - 0.32 11.1 0.0 0.32 11.1 0.0 7.0 5 2 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 CDJ47580.1 - 1 8.0 18.3 2.2 7.0 18.3 1.5 1 0 0 1 1 1 0 Presenilin DUF4179 PF13786.6 CDJ47580.1 - 1.6 9.2 8.0 12 6.5 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) CLN3 PF02487.17 CDJ47580.1 - 1.8 7.5 3.9 3.4 6.6 3.9 1.5 1 0 0 1 1 1 0 CLN3 protein IMP2_N PF18590.1 CDJ47581.1 - 8.6e-22 77.5 0.2 1.3e-14 54.5 0.1 2.3 1 1 1 2 2 2 2 Immune Mapped Protein 2 (IMP2) N-terminal domain SR-25 PF10500.9 CDJ47582.1 - 3.1 7.4 12.2 2 8.0 10.5 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF5349 PF17298.2 CDJ47582.1 - 3.3 7.4 10.7 4.2 7.0 10.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) AF-4 PF05110.13 CDJ47582.1 - 7.7 4.5 7.3 9.8 4.1 7.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4518 PF15008.6 CDJ47583.1 - 0.013 14.7 3.7 0.018 14.2 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) SARAF PF06682.12 CDJ47583.1 - 0.015 14.9 5.6 0.026 14.2 5.6 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4492 PF14899.6 CDJ47583.1 - 0.56 10.2 0.1 0.56 10.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) DUF2973 PF11189.8 CDJ47583.1 - 1.3 9.2 3.4 2.4 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) SnAPC_2_like PF11035.8 CDJ47583.1 - 5.4 7.1 22.0 7.4 6.6 22.0 1.3 1 1 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF3464 PF11947.8 CDJ47583.1 - 8.8 6.1 8.4 14 5.4 7.1 2.1 1 1 1 2 2 2 0 Photosynthesis affected mutant 68 SUIM_assoc PF16619.5 CDJ47584.1 - 0.059 13.4 15.0 0.11 12.5 15.0 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ47584.1 - 0.2 11.6 26.8 0.25 11.3 26.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM199X PF15814.5 CDJ47584.1 - 0.22 10.5 29.1 0.37 9.8 29.1 1.4 1 1 0 1 1 1 0 Protein family FAM199X Spem1 PF15670.5 CDJ47584.1 - 0.28 10.7 6.9 0.32 10.5 6.9 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 eIF-3_zeta PF05091.12 CDJ47584.1 - 1.5 7.7 10.8 1.5 7.7 10.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ47584.1 - 3.5 7.6 5.1 4.2 7.4 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 CDJ47584.1 - 3.8 7.1 15.8 5.1 6.6 15.8 1.3 1 0 0 1 1 1 0 Spt20 family DUF3682 PF12446.8 CDJ47585.1 - 0.0045 17.5 22.2 0.0045 17.5 22.2 11.7 7 4 4 11 11 11 1 Protein of unknown function (DUF3682) Pex14_N PF04695.13 CDJ47585.1 - 0.0054 17.4 18.9 0.0054 17.4 18.9 7.8 4 3 2 6 6 6 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RRM_1 PF00076.22 CDJ47587.1 - 1e-33 114.9 0.2 1.4e-15 56.9 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ47587.1 - 1.4e-06 28.3 0.1 0.025 14.7 0.0 3.0 2 2 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 CDJ47587.1 - 0.026 14.2 0.1 0.39 10.4 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Syntaxin-5_N PF11416.8 CDJ47588.1 - 0.18 11.1 0.5 0.32 10.3 0.5 1.4 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain Fis1_TPR_C PF14853.6 CDJ47589.1 - 0.0018 18.3 1.9 0.004 17.2 0.2 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat PTS_EIIA_2 PF00359.22 CDJ47589.1 - 0.044 13.7 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 UCH PF00443.29 CDJ47589.1 - 0.066 12.7 0.2 0.12 11.8 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase N1221 PF07923.13 CDJ47589.1 - 0.074 12.2 2.2 0.2 10.8 1.3 2.0 2 0 0 2 2 2 0 N1221-like protein Ipi1_N PF12333.8 CDJ47589.1 - 0.077 13.6 5.3 3.7 8.2 0.1 4.7 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Spt20 PF12090.8 CDJ47589.1 - 0.35 10.4 32.6 0.14 11.8 12.0 3.6 3 0 0 3 3 3 0 Spt20 family PigN PF04987.14 CDJ47589.1 - 0.61 8.9 1.7 1.1 8.1 1.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) RCR PF12273.8 CDJ47589.1 - 5.2 7.7 6.5 5.9 7.6 1.2 2.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Nop PF01798.18 CDJ47590.1 - 1.1e-76 257.4 0.2 3.2e-76 255.8 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CDJ47590.1 - 3.7e-13 49.7 0.9 1.4e-12 47.8 0.9 2.1 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Ribosomal_60s PF00428.19 CDJ47590.1 - 3.1 8.5 42.7 4.9 7.8 5.0 3.8 4 0 0 4 4 4 0 60s Acidic ribosomal protein PIP5K PF01504.18 CDJ47591.1 - 5.4e-06 25.8 0.0 5.4e-06 25.8 0.0 5.7 5 2 1 6 6 6 1 Phosphatidylinositol-4-phosphate 5-Kinase Spt20 PF12090.8 CDJ47591.1 - 0.0031 17.2 13.7 0.0031 17.2 13.7 6.7 5 1 0 6 6 6 2 Spt20 family Cpn60_TCP1 PF00118.24 CDJ47591.1 - 0.025 13.2 0.0 0.045 12.4 0.0 1.4 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family NFACT-R_1 PF05670.13 CDJ47592.1 - 9.7e-07 29.4 11.9 0.00025 21.7 6.1 3.2 2 1 0 2 2 2 1 NFACT protein RNA binding domain PTPRCAP PF15713.5 CDJ47592.1 - 0.015 15.6 17.2 0.015 15.6 17.2 3.3 3 1 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated SID-1_RNA_chan PF13965.6 CDJ47592.1 - 0.13 10.6 2.6 0.17 10.3 2.6 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Afi1 PF07792.12 CDJ47592.1 - 0.15 12.6 19.4 0.036 14.6 13.3 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF572 PF04502.13 CDJ47592.1 - 0.5 9.9 27.0 0.86 9.2 27.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S64 PF08192.11 CDJ47592.1 - 1.8 7.0 28.7 2.5 6.5 28.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Bul1_N PF04425.12 CDJ47592.1 - 2.4 6.8 15.7 3.6 6.2 15.7 1.3 1 0 0 1 1 1 0 Bul1 N terminus CSG2 PF16965.5 CDJ47592.1 - 5.4 5.9 9.6 9.9 5.0 9.6 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator DNA_topoisoIV PF00521.20 CDJ47593.1 - 8.5e-58 196.2 6.2 3.3e-34 118.5 0.0 2.4 1 1 1 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 CDJ47593.1 - 0.00036 19.9 0.0 0.016 14.7 0.0 2.4 2 0 0 2 2 2 1 DNA gyrase C-terminal domain, beta-propeller RVT_1 PF00078.27 CDJ47594.1 - 3.5e-06 26.7 0.0 5.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FRQ PF09421.10 CDJ47596.1 - 0.061 11.4 9.6 0.04 12.0 8.4 1.2 1 1 0 1 1 1 0 Frequency clock protein CAF1 PF04857.20 CDJ47596.1 - 0.35 10.0 8.6 0.36 10.0 8.6 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease Mucin15 PF15672.5 CDJ47596.1 - 0.42 10.1 5.3 0.5 9.8 5.3 1.1 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Fumble PF03630.14 CDJ47596.1 - 3.7 6.6 8.1 5.6 6.0 8.1 1.3 1 0 0 1 1 1 0 Fumble Bul1_N PF04425.12 CDJ47596.1 - 8 5.1 17.5 14 4.3 17.5 1.3 1 0 0 1 1 1 0 Bul1 N terminus Membralin PF09746.9 CDJ47596.1 - 9.9 5.1 14.0 16 4.4 14.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein LSM14 PF12701.7 CDJ47597.1 - 1.5e-24 85.9 0.0 2.6e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 CDJ47597.1 - 3.4e-06 27.1 0.0 6.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 CDJ47597.1 - 0.004 18.0 18.6 0.13 13.1 1.3 3.3 2 1 1 3 3 3 2 FDF domain Spt20 PF12090.8 CDJ47597.1 - 1.1 8.8 22.6 1.5 8.4 10.8 2.1 2 0 0 2 2 2 0 Spt20 family Pex14_N PF04695.13 CDJ47597.1 - 7.5 7.2 10.7 8.3 7.1 4.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.9 CDJ47599.1 - 0.0001 22.0 25.9 0.0001 22.0 25.9 10.1 5 3 4 10 10 10 2 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ47599.1 - 0.0095 16.2 8.2 0.0095 16.2 8.2 16.3 8 3 6 15 15 15 3 Early growth response N-terminal domain Androgen_recep PF02166.16 CDJ47601.1 - 0.0052 15.7 12.2 0.0052 15.7 12.2 7.3 3 2 5 8 8 8 2 Androgen receptor Apt1 PF10351.9 CDJ47602.1 - 4.9e-05 22.4 5.2 4.9e-05 22.4 5.2 4.2 3 1 1 4 4 4 2 Golgi-body localisation protein domain Mucin PF01456.17 CDJ47602.1 - 0.00095 19.2 0.0 0.00095 19.2 0.0 6.3 4 2 3 7 7 7 1 Mucin-like glycoprotein YfhO PF09586.10 CDJ47602.1 - 0.0066 14.7 0.2 0.0066 14.7 0.2 4.0 3 1 0 3 3 3 1 Bacterial membrane protein YfhO Pdase_M17_N2 PF18295.1 CDJ47603.1 - 0.0084 16.4 0.7 0.012 15.9 0.7 1.3 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 ANAPC_CDC26 PF10471.9 CDJ47603.1 - 0.0097 16.7 32.5 0.19 12.6 15.5 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex APC subunit CDC26 IHABP4_N PF16174.5 CDJ47603.1 - 0.098 13.3 18.9 0.12 13.0 18.9 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal PGA2 PF07543.12 CDJ47603.1 - 0.29 11.1 11.2 0.38 10.7 11.2 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Hep_59 PF07052.11 CDJ47603.1 - 0.38 11.5 15.3 1.2 9.9 1.9 2.3 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Presenilin PF01080.17 CDJ47603.1 - 0.39 9.4 19.4 0.43 9.3 19.4 1.0 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 CDJ47603.1 - 0.44 10.6 17.0 0.47 10.6 17.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2828 PF11443.8 CDJ47603.1 - 0.57 8.2 13.5 0.65 8.0 13.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 CDJ47603.1 - 0.99 8.3 8.7 1.1 8.1 8.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4175 PF13779.6 CDJ47603.1 - 1.6 6.6 27.9 1.7 6.5 27.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4647 PF15504.6 CDJ47603.1 - 1.7 7.7 21.6 1.9 7.5 21.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) EphA2_TM PF14575.6 CDJ47603.1 - 1.8 9.5 10.7 6.7 7.7 0.3 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain HGTP_anticodon2 PF12745.7 CDJ47603.1 - 2 7.9 14.6 2.3 7.7 14.6 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs SLC12 PF03522.15 CDJ47603.1 - 2.4 7.1 16.5 2.5 7.0 16.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 CDJ47603.1 - 3.8 6.2 15.9 4.4 6.0 15.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2681 PF10883.8 CDJ47603.1 - 6.4 7.3 29.0 1.6 9.2 12.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF2722 PF10846.8 CDJ47603.1 - 7.5 5.4 39.8 0.31 9.9 21.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) UPF0239 PF06783.11 CDJ47603.1 - 8.7 6.6 13.8 14 5.9 0.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) SID-1_RNA_chan PF13965.6 CDJ47603.1 - 9.5 4.5 7.1 11 4.2 7.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Atg14 PF10186.9 CDJ47604.1 - 0.07 12.2 18.8 0.12 11.4 18.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 CDJ47604.1 - 0.36 8.7 6.1 0.44 8.4 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paramyxo_ncap PF00973.19 CDJ47604.1 - 0.86 8.4 8.6 1.4 7.8 8.6 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SKA1 PF07160.12 CDJ47604.1 - 0.98 9.2 15.7 1.5 8.6 15.7 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 LMBR1 PF04791.16 CDJ47604.1 - 1.4 7.8 2.2 1.8 7.4 2.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein BshC PF10079.9 CDJ47604.1 - 2.4 6.8 15.6 2.4 6.8 14.3 1.5 1 1 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF4407 PF14362.6 CDJ47607.1 - 0.0077 15.6 2.2 0.0083 15.5 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Activator_LAG-3 PF11498.8 CDJ47607.1 - 0.044 12.8 36.4 0.051 12.5 36.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Neur_chan_memb PF02932.16 CDJ47607.1 - 0.46 10.5 3.7 0.49 10.4 3.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.10 CDJ47607.1 - 0.54 10.3 8.5 0.61 10.1 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.12 CDJ47607.1 - 1.8 7.4 12.0 2 7.3 12.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 CDJ47607.1 - 3.7 7.1 31.3 4.7 6.8 31.3 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ47607.1 - 4.9 7.0 30.3 6 6.7 30.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 CDJ47607.1 - 7.1 6.6 16.6 9.2 6.3 16.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 CDJ47607.1 - 7.4 5.2 11.1 8.8 5.0 11.1 1.0 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ47607.1 - 8.7 7.4 11.0 13 6.8 11.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EIF4E-T PF10477.9 CDJ47607.1 - 8.8 5.0 19.6 11 4.7 19.6 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DJ-1_PfpI PF01965.24 CDJ47608.1 - 9.3e-15 54.8 0.1 1.2e-14 54.4 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF2722 PF10846.8 CDJ47609.1 - 0.002 17.1 15.3 0.002 17.1 15.3 6.2 5 1 0 5 5 5 3 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ47609.1 - 0.21 11.9 0.1 0.21 11.9 0.1 6.4 1 1 2 5 5 5 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ47610.1 - 0.0009 19.4 20.3 0.00099 19.2 20.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ47610.1 - 0.011 14.7 8.8 0.011 14.7 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 CDJ47610.1 - 0.054 13.6 5.4 0.057 13.5 5.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MLANA PF14991.6 CDJ47610.1 - 0.089 13.1 2.8 0.14 12.4 2.8 1.3 1 0 0 1 1 1 0 Protein melan-A DUF4834 PF16118.5 CDJ47610.1 - 0.16 12.9 2.3 0.23 12.5 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) BAF1_ABF1 PF04684.13 CDJ47610.1 - 0.18 10.8 6.8 0.27 10.2 6.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pex14_N PF04695.13 CDJ47610.1 - 0.19 12.4 20.6 0.25 12.0 20.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tic110 PF16940.5 CDJ47610.1 - 0.25 9.8 14.8 0.025 13.1 6.9 2.0 2 0 0 2 2 2 0 Chloroplast envelope transporter Presenilin PF01080.17 CDJ47610.1 - 0.27 9.9 5.3 0.33 9.7 5.3 1.1 1 0 0 1 1 1 0 Presenilin Activator_LAG-3 PF11498.8 CDJ47610.1 - 0.54 9.2 27.4 0.82 8.6 27.4 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ47610.1 - 0.55 9.8 23.4 0.69 9.5 23.4 1.1 1 0 0 1 1 1 0 Spt20 family SAP130_C PF16014.5 CDJ47610.1 - 0.7 8.9 16.4 0.88 8.6 16.4 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus BAT2_N PF07001.11 CDJ47610.1 - 0.9 10.0 16.2 1.5 9.2 16.2 1.4 1 0 0 1 1 1 0 BAT2 N-terminus DUF702 PF05142.12 CDJ47610.1 - 0.93 10.0 8.7 1.2 9.6 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) PAT1 PF09770.9 CDJ47610.1 - 1.1 7.5 15.8 1.2 7.3 15.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EIF4E-T PF10477.9 CDJ47610.1 - 1.1 8.0 13.5 1.3 7.7 13.5 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E GREB1 PF15782.5 CDJ47610.1 - 1.2 6.2 8.5 1.4 5.9 8.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5521 PF17659.1 CDJ47610.1 - 1.7 6.4 8.2 1.9 6.2 8.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Wyosine_form PF08608.12 CDJ47612.1 - 1.2e-19 70.4 0.0 1.9e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Wyosine base formation SPX PF03105.19 CDJ47612.1 - 0.011 15.6 0.5 0.011 15.6 0.5 1.1 1 0 0 1 1 1 0 SPX domain GEMIN8 PF15348.6 CDJ47612.1 - 0.049 13.9 0.0 0.072 13.4 0.0 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Apt1 PF10351.9 CDJ47612.1 - 0.22 10.3 3.6 0.27 10.0 3.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ47612.1 - 1.3 7.5 12.8 1.8 7.0 12.8 1.1 1 0 0 1 1 1 0 Macoilin family DUF515 PF04415.12 CDJ47612.1 - 1.8 6.9 19.2 2.4 6.4 19.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF1180 PF06679.12 CDJ47612.1 - 2.5 8.5 4.4 4.5 7.7 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CCDC24 PF15669.5 CDJ47612.1 - 5.6 6.8 5.6 9.7 6.0 5.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family REV PF00424.18 CDJ47613.1 - 0.074 13.1 0.6 0.19 11.8 0.6 1.7 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Ocnus PF05005.15 CDJ47614.1 - 2.7e-22 78.9 0.2 4.7e-22 78.1 0.2 1.3 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) DUF3323 PF11796.8 CDJ47614.1 - 0.024 14.5 1.4 0.045 13.6 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) ALMT PF11744.8 CDJ47614.1 - 1.8 7.3 4.2 2.5 6.9 3.8 1.4 1 1 1 2 2 2 0 Aluminium activated malate transporter E1_dh PF00676.20 CDJ47615.1 - 6.8e-82 274.8 0.0 1e-81 274.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component MAR_sialic_bdg PF10564.9 CDJ47615.1 - 2.8e-14 52.9 0.8 5.3e-14 52.0 0.8 1.4 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat TPP_enzyme_C PF02775.21 CDJ47615.1 - 2e-10 40.7 1.3 3.4e-10 39.9 0.3 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 CDJ47615.1 - 0.00033 19.9 0.0 0.00056 19.2 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 CDJ47615.1 - 0.0014 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain MAR_sialic_bdg PF10564.9 CDJ47617.1 - 7e-111 362.6 37.2 1.8e-25 88.8 0.7 5.2 5 0 0 5 5 5 5 Sialic-acid binding micronemal adhesive repeat SOG2 PF10428.9 CDJ47620.1 - 0.013 14.7 23.0 0.017 14.3 23.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Lin-8 PF03353.15 CDJ47620.1 - 3.2 7.2 25.6 0.15 11.6 13.5 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Miga PF10265.9 CDJ47620.1 - 6.3 5.7 9.0 12 4.8 9.0 1.3 1 0 0 1 1 1 0 Mitoguardin Caldesmon PF02029.15 CDJ47622.1 - 0.096 11.4 44.0 0.13 11.0 44.0 1.2 1 0 0 1 1 1 0 Caldesmon DUF2362 PF10154.9 CDJ47623.1 - 1.2e-07 31.1 0.0 1.2e-07 31.1 0.0 4.2 2 2 1 3 3 3 1 Uncharacterized conserved protein (DUF2362) YliH PF10799.8 CDJ47623.1 - 0.12 12.3 2.0 0.36 10.8 2.0 1.8 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) REV PF00424.18 CDJ47623.1 - 3.9 7.6 9.5 0.22 11.6 1.0 3.0 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Neur_chan_memb PF02932.16 CDJ47625.1 - 0.82 9.7 24.2 0.59 10.1 6.6 3.9 4 0 0 4 4 4 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 CDJ47626.1 - 0.0011 18.5 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Shisa PF13908.6 CDJ47626.1 - 0.002 18.4 3.2 0.002 18.4 3.2 1.7 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator BatD PF13584.6 CDJ47626.1 - 0.003 16.5 7.9 0.0038 16.1 6.6 1.9 1 1 0 1 1 1 1 Oxygen tolerance Connexin PF00029.19 CDJ47626.1 - 0.0032 17.3 0.2 0.0046 16.7 0.2 1.2 1 0 0 1 1 1 1 Connexin DUF4598 PF15370.6 CDJ47626.1 - 0.02 15.4 3.9 0.02 15.4 3.9 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4598) Sporozoite_P67 PF05642.11 CDJ47626.1 - 0.021 12.9 0.0 0.027 12.6 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LMBR1 PF04791.16 CDJ47626.1 - 0.022 13.7 5.4 0.032 13.1 5.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein FA_desaturase PF00487.24 CDJ47626.1 - 0.024 14.5 1.1 0.024 14.5 1.1 1.5 1 1 1 2 2 2 0 Fatty acid desaturase COX15-CtaA PF02628.15 CDJ47626.1 - 0.074 12.1 16.8 0.57 9.2 16.8 2.0 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein Dpy19 PF10034.9 CDJ47626.1 - 0.089 11.0 5.9 0.1 10.8 5.9 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation RIFIN PF02009.16 CDJ47626.1 - 0.12 12.2 10.1 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 Rifin DUF2207 PF09972.9 CDJ47626.1 - 0.12 11.1 7.0 0.18 10.6 6.1 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Sarcoglycan_2 PF05510.13 CDJ47626.1 - 0.19 10.5 9.3 0.051 12.3 6.2 1.6 1 1 1 2 2 2 0 Sarcoglycan alpha/epsilon Scs3p PF10261.9 CDJ47626.1 - 0.28 10.6 7.2 0.11 11.9 4.3 1.7 1 1 1 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM BSMAP PF12280.8 CDJ47626.1 - 0.31 11.2 12.2 0.73 10.0 12.2 1.6 1 1 0 1 1 1 0 Brain specific membrane anchored protein DUF1189 PF06691.11 CDJ47626.1 - 0.41 10.2 5.9 0.52 9.8 5.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1189) Orf78 PF06024.12 CDJ47626.1 - 0.57 10.5 15.4 0.029 14.7 8.4 2.4 2 1 1 3 3 2 0 Orf78 (ac78) Amnionless PF14828.6 CDJ47626.1 - 0.63 8.8 8.5 0.41 9.4 7.1 1.4 1 1 0 1 1 1 0 Amnionless Peroxin-3 PF04882.12 CDJ47626.1 - 0.86 8.5 18.7 0.041 12.9 13.5 1.4 2 0 0 2 2 2 0 Peroxin-3 eIF-3_zeta PF05091.12 CDJ47626.1 - 1.2 8.0 13.4 1.7 7.5 13.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Anoctamin PF04547.12 CDJ47626.1 - 2.1 7.1 8.5 1.2 7.9 6.9 1.4 1 1 0 1 1 1 0 Calcium-activated chloride channel DUF2417 PF10329.9 CDJ47626.1 - 2.2 7.6 8.5 0.35 10.3 3.5 1.8 1 1 0 1 1 1 0 Region of unknown function (DUF2417) RR_TM4-6 PF06459.12 CDJ47626.1 - 2.5 7.9 9.9 4.5 7.0 9.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rpp20 PF12328.8 CDJ47626.1 - 2.5 8.0 11.2 6.2 6.8 11.2 1.7 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF4834 PF16118.5 CDJ47626.1 - 2.5 9.1 0.0 2.5 9.1 0.0 2.9 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 CDJ47626.1 - 3.2 7.8 8.7 5.7 6.9 8.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4400 PF14348.6 CDJ47626.1 - 3.8 6.9 16.4 0.032 13.7 3.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4400) DC_STAMP PF07782.13 CDJ47626.1 - 4.1 7.2 8.9 0.068 13.0 2.1 1.5 2 0 0 2 2 1 0 DC-STAMP-like protein FAM60A PF15396.6 CDJ47626.1 - 5.6 6.9 6.9 8.6 6.3 6.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Ctr PF04145.15 CDJ47626.1 - 6 7.5 11.9 4.5 7.9 9.9 1.7 1 1 1 2 2 2 0 Ctr copper transporter family CPSF100_C PF13299.6 CDJ47626.1 - 8.2 6.6 10.7 1 9.5 5.3 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 CDJ47626.1 - 8.7 6.4 12.6 12 5.9 12.6 1.5 1 1 0 1 1 1 0 DDHD domain TMEM154 PF15102.6 CDJ47626.1 - 8.7 6.2 16.0 0.13 12.1 3.3 2.4 2 1 0 2 2 2 0 TMEM154 protein family Nop14 PF04147.12 CDJ47627.1 - 0.6 8.3 5.9 0.86 7.7 5.9 1.3 1 0 0 1 1 1 0 Nop14-like family Dehydrin PF00257.19 CDJ47628.1 - 0.0054 17.3 12.7 0.0083 16.7 12.7 1.2 1 0 0 1 1 1 1 Dehydrin RIFIN PF02009.16 CDJ47628.1 - 0.87 9.4 4.5 1 9.2 4.5 1.2 1 0 0 1 1 1 0 Rifin CCDC106 PF15794.5 CDJ47628.1 - 0.97 9.1 4.8 1.1 8.9 4.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 AF-4 PF05110.13 CDJ47628.1 - 1 7.3 10.6 1 7.3 10.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RskA PF10099.9 CDJ47628.1 - 1.8 8.8 19.0 2.2 8.6 19.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Myc_N PF01056.18 CDJ47628.1 - 7.4 6.4 10.3 8.7 6.1 10.3 1.0 1 0 0 1 1 1 0 Myc amino-terminal region PAP1 PF08601.10 CDJ47628.1 - 7.6 6.1 14.6 8.9 5.9 14.6 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 GREB1 PF15782.5 CDJ47628.1 - 8 3.4 8.4 9 3.3 8.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SPX PF03105.19 CDJ47629.1 - 0.0048 16.9 5.1 0.0048 16.9 5.1 2.1 2 0 0 2 2 2 1 SPX domain HEXIM PF15313.6 CDJ47629.1 - 0.011 15.9 0.3 0.036 14.3 0.3 1.9 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein ATP-grasp_2 PF08442.10 CDJ47630.1 - 9.2e-32 110.3 3.5 1.4e-26 93.4 2.9 2.3 1 1 1 2 2 2 2 ATP-grasp domain SDA1 PF05285.12 CDJ47630.1 - 6.4e-06 25.8 12.0 9e-06 25.3 12.0 1.1 1 0 0 1 1 1 1 SDA1 ATP-grasp_5 PF13549.6 CDJ47630.1 - 0.0015 18.1 0.4 0.0031 17.0 0.1 1.6 1 1 0 1 1 1 1 ATP-grasp domain dsDNA_bind PF01984.20 CDJ47630.1 - 0.011 16.0 4.4 0.011 16.0 4.4 3.7 3 1 0 3 3 3 0 Double-stranded DNA-binding domain MCU PF04678.13 CDJ47630.1 - 0.012 15.7 0.4 0.012 15.7 0.4 2.8 2 1 1 3 3 3 0 Mitochondrial calcium uniporter DUF4366 PF14283.6 CDJ47630.1 - 0.016 15.3 5.9 0.13 12.3 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 CDJ47630.1 - 0.021 13.6 31.0 0.11 11.2 18.0 2.2 2 0 0 2 2 2 0 Presenilin GARS_A PF01071.19 CDJ47630.1 - 0.12 12.1 0.3 1.1 9.0 0.3 2.4 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Radical_SAM_N PF08497.10 CDJ47630.1 - 5.6 6.1 9.1 0.18 11.0 2.1 1.8 2 0 0 2 2 2 0 Radical SAM N-terminal Med3 PF11593.8 CDJ47631.1 - 0.00055 19.2 8.4 0.00055 19.2 8.4 3.2 3 1 0 3 3 3 1 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ47631.1 - 0.51 10.6 52.5 0.053 13.8 13.9 4.5 2 1 3 5 5 5 0 Anti-sigma-K factor rskA Mlh1_C PF16413.5 CDJ47631.1 - 6.5 6.0 7.1 9.7 5.5 0.0 2.6 3 0 0 3 3 3 0 DNA mismatch repair protein Mlh1 C-terminus Gram_pos_anchor PF00746.21 CDJ47632.1 - 9.2 6.3 11.0 0.14 12.1 1.2 3.0 3 0 0 3 3 3 0 LPXTG cell wall anchor motif PITH PF06201.13 CDJ47633.1 - 4.2e-28 98.5 0.0 4.8e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.13 CDJ47633.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal DUF3876 PF12992.7 CDJ47633.1 - 0.092 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) DUF572 PF04502.13 CDJ47634.1 - 0.42 10.2 17.7 0.54 9.8 17.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Citrate_synt PF00285.21 CDJ47634.1 - 0.51 9.3 7.3 0.66 9.0 7.3 1.1 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain Ribosomal_60s PF00428.19 CDJ47634.1 - 0.98 10.0 13.4 2.4 8.8 13.4 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4551 PF15087.6 CDJ47634.1 - 2.6 6.8 26.2 3.1 6.5 26.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TCP PF03634.13 CDJ47636.1 - 0.0075 16.8 58.0 0.11 13.1 31.4 3.5 3 0 0 3 3 3 3 TCP family transcription factor N6_N4_Mtase PF01555.18 CDJ47636.1 - 0.014 15.1 0.0 0.38 10.4 0.0 2.7 1 1 0 1 1 1 0 DNA methylase CNDH2_C PF16858.5 CDJ47636.1 - 2.6 7.9 47.8 0.28 11.0 20.5 3.1 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4207 PF13904.6 CDJ47636.1 - 2.7 7.6 84.7 0.014 15.1 39.5 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) Tim54 PF11711.8 CDJ47636.1 - 5 5.8 47.0 0.37 9.5 19.1 3.3 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.25 CDJ47640.1 - 1.2e-37 129.7 0.0 2.1e-17 63.4 0.1 3.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ47640.1 - 2.1e-10 40.3 0.2 3.1e-05 23.4 0.1 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase AMP-binding PF00501.28 CDJ47641.1 - 0.0075 14.9 6.1 0.63 8.6 1.0 3.0 2 1 0 2 2 2 2 AMP-binding enzyme RAB3GAP2_N PF14655.6 CDJ47641.1 - 0.19 10.9 3.7 9.3 5.4 0.0 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus M-factor PF03855.13 CDJ47641.1 - 0.38 10.9 0.1 0.38 10.9 0.1 3.1 4 0 0 4 4 4 0 M-factor DUF2722 PF10846.8 CDJ47641.1 - 0.66 8.8 9.0 0.22 10.4 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Acetyltransf_1 PF00583.25 CDJ47642.1 - 1.3e-16 60.8 0.0 1.7e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ47642.1 - 6.9e-13 48.7 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ47642.1 - 5e-12 46.1 0.0 6.8e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CDJ47642.1 - 3.3e-08 34.3 0.0 5.1e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ47642.1 - 7.2e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 CDJ47642.1 - 0.00028 20.8 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 CDJ47642.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDJ47642.1 - 0.037 14.1 0.0 0.099 12.7 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 CDJ47642.1 - 0.058 13.0 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase GNAT_acetyltr_2 PF13718.6 CDJ47642.1 - 0.099 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_4 PF13420.7 CDJ47642.1 - 0.21 11.7 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF508 PF04370.12 CDJ47643.1 - 0.18 11.5 5.4 0.43 10.3 5.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Secretin_N_2 PF07655.13 CDJ47643.1 - 3 8.5 15.5 0.15 12.7 9.0 2.2 2 1 0 2 2 2 0 Secretin N-terminal domain DUF572 PF04502.13 CDJ47643.1 - 5 6.6 14.8 3.7 7.1 9.5 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) TFIIA PF03153.13 CDJ47645.1 - 0.00024 21.3 14.0 0.00036 20.7 14.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ47645.1 - 0.0031 17.8 2.9 0.0031 17.8 2.9 2.3 1 1 0 2 2 2 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ47645.1 - 0.12 11.2 12.7 0.12 11.3 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) CENP-B_dimeris PF09026.10 CDJ47645.1 - 0.41 11.1 3.7 0.72 10.3 3.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain U1snRNP70_N PF12220.8 CDJ47645.1 - 1.6 9.4 9.8 4.4 8.0 0.9 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Sporozoite_P67 PF05642.11 CDJ47645.1 - 1.7 6.7 11.3 0.2 9.7 1.7 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Cnd2 PF05786.14 CDJ47645.1 - 3.2 6.3 11.2 0.56 8.8 5.9 2.0 2 0 0 2 2 2 0 Condensin complex subunit 2 Calici_coat PF00915.20 CDJ47645.1 - 8.9 5.1 6.2 13 4.5 6.2 1.2 1 0 0 1 1 1 0 Calicivirus coat protein DAGK_cat PF00781.24 CDJ47647.1 - 2.3e-14 53.1 0.0 6.2e-14 51.7 0.0 1.8 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF1645 PF07816.11 CDJ47647.1 - 0.01 16.4 1.1 0.01 16.4 1.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF3446 PF11928.8 CDJ47647.1 - 0.037 14.3 6.5 0.054 13.8 2.4 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF2722 PF10846.8 CDJ47647.1 - 0.041 12.8 6.1 0.061 12.3 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ANAPC_CDC26 PF10471.9 CDJ47647.1 - 0.047 14.5 4.0 0.047 14.5 4.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CDJ47647.1 - 0.12 12.0 6.6 0.18 11.4 6.6 1.3 1 0 0 1 1 1 0 Spt20 family MRI PF15325.6 CDJ47647.1 - 0.12 13.4 0.1 0.12 13.4 0.1 2.2 3 0 0 3 3 2 0 Modulator of retrovirus infection EphA2_TM PF14575.6 CDJ47647.1 - 0.19 12.6 0.2 0.58 11.1 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 CDJ47647.1 - 0.49 10.2 11.5 2.5 7.9 11.3 2.0 1 1 1 2 2 2 0 Transmembrane protein 51 Caskin1-CID PF16600.5 CDJ47647.1 - 6.7 7.4 12.2 0.094 13.3 4.4 1.9 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain Conotoxin PF02950.17 CDJ47647.1 - 9.9 7.3 6.0 1.5 9.9 0.7 2.3 3 0 0 3 3 3 0 Conotoxin Adeno_PV PF03910.13 CDJ47648.1 - 2.9 6.5 10.0 3.4 6.3 10.0 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF3138 PF11336.8 CDJ47648.1 - 6.6 5.2 11.0 6.9 5.2 11.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TFIIF_alpha PF05793.12 CDJ47649.1 - 3.5 6.1 35.3 5.1 5.6 35.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) WD40 PF00400.32 CDJ47651.1 - 0.0011 19.7 0.1 2.8 9.0 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat PIEZO PF15917.5 CDJ47651.1 - 0.0089 15.5 13.8 0.013 15.0 13.8 1.2 1 0 0 1 1 1 1 Piezo SpoIIP PF07454.11 CDJ47651.1 - 0.017 14.6 9.0 0.024 14.1 9.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PAT1 PF09770.9 CDJ47651.1 - 0.055 11.8 25.3 0.065 11.5 25.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 CDJ47651.1 - 0.13 11.2 8.0 0.56 9.2 9.0 1.5 2 0 0 2 2 2 0 Solute carrier family 12 eIF-3_zeta PF05091.12 CDJ47651.1 - 0.17 10.8 17.8 0.23 10.4 17.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sin_N PF04801.13 CDJ47651.1 - 0.26 10.4 19.2 0.45 9.7 19.2 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region OATP PF03137.20 CDJ47651.1 - 0.48 8.7 7.3 0.61 8.3 2.3 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ALMT PF11744.8 CDJ47651.1 - 0.64 8.8 6.0 1 8.1 6.0 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Membralin PF09746.9 CDJ47651.1 - 1.1 8.3 5.9 1.5 7.8 5.9 1.2 1 0 0 1 1 1 0 Tumour-associated protein Suf PF05843.14 CDJ47651.1 - 1.2 9.1 18.3 2.7 7.9 18.3 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Lin-8 PF03353.15 CDJ47651.1 - 1.6 8.2 22.7 4.3 6.8 17.4 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.13 CDJ47651.1 - 1.7 8.4 11.3 0.11 12.3 6.4 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain V_ATPase_I PF01496.19 CDJ47651.1 - 2 6.3 10.9 2.6 5.8 10.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spem1 PF15670.5 CDJ47651.1 - 2.3 7.7 17.3 0.02 14.5 8.3 1.9 2 0 0 2 2 2 0 Spermatid maturation protein 1 Tim54 PF11711.8 CDJ47651.1 - 2.3 6.9 12.9 3.9 6.2 12.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4770 PF15994.5 CDJ47651.1 - 2.9 8.1 20.8 4.6 7.4 20.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Glt_symporter PF03616.14 CDJ47651.1 - 3 6.4 7.7 0.12 11.1 1.3 1.8 2 0 0 2 2 2 0 Sodium/glutamate symporter FAM176 PF14851.6 CDJ47651.1 - 3 7.5 7.3 6.6 6.4 7.3 1.5 1 0 0 1 1 1 0 FAM176 family SR-25 PF10500.9 CDJ47651.1 - 4 7.0 31.8 0.21 11.1 3.3 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FAM60A PF15396.6 CDJ47651.1 - 4.6 7.2 13.0 1.9 8.4 8.3 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DUF3408 PF11888.8 CDJ47651.1 - 4.7 7.4 15.3 10 6.2 15.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) XRN_N PF03159.18 CDJ47651.1 - 4.8 6.5 10.0 7 6.0 10.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Folate_carrier PF01770.18 CDJ47651.1 - 7.4 5.2 8.4 12 4.4 8.4 1.3 1 0 0 1 1 1 0 Reduced folate carrier EPL1 PF10513.9 CDJ47651.1 - 8.3 6.8 16.9 0.16 12.3 9.4 1.9 2 1 0 2 2 2 0 Enhancer of polycomb-like EOS1 PF12326.8 CDJ47651.1 - 8.9 6.2 9.6 3.9 7.4 6.1 1.9 2 1 0 2 2 2 0 N-glycosylation protein Ndc1_Nup PF09531.10 CDJ47651.1 - 9.1 4.8 18.8 0.39 9.3 13.2 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup RskA PF10099.9 CDJ47653.1 - 0.013 15.8 13.1 0.013 15.8 13.1 3.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA SPX PF03105.19 CDJ47655.1 - 0.0014 18.6 14.1 0.0014 18.6 14.1 12.9 9 2 0 9 9 9 6 SPX domain Apt1 PF10351.9 CDJ47656.1 - 0.77 8.5 0.0 0.77 8.5 0.0 7.7 4 3 2 6 6 6 0 Golgi-body localisation protein domain AF-4 PF05110.13 CDJ47657.1 - 0.02 13.0 26.2 0.023 12.8 26.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Dsh_C PF12316.8 CDJ47657.1 - 0.076 13.4 22.5 0.095 13.1 22.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CCSAP PF15748.5 CDJ47657.1 - 2.2 8.4 18.8 2.9 8.0 18.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF966 PF06136.13 CDJ47657.1 - 3.1 7.4 18.2 3.5 7.3 18.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peptidase_S64 PF08192.11 CDJ47657.1 - 4.3 5.7 12.1 5.3 5.4 12.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 FAM199X PF15814.5 CDJ47657.1 - 4.7 6.2 12.5 6.4 5.7 12.5 1.3 1 0 0 1 1 1 0 Protein family FAM199X DUF3474 PF11960.8 CDJ47657.1 - 6.9 6.9 6.7 9.3 6.5 6.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) GREB1 PF15782.5 CDJ47657.1 - 7.5 3.5 15.8 9.9 3.1 15.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HECT PF00632.25 CDJ47658.1 - 1.3e-32 113.5 0.0 7.3e-32 111.1 0.0 2.1 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RskA PF10099.9 CDJ47658.1 - 1.9e-05 25.0 4.2 1.9e-05 25.0 4.2 16.3 8 5 5 13 13 13 1 Anti-sigma-K factor rskA BTB PF00651.31 CDJ47659.1 - 1.4e-15 57.4 0.0 8.8e-15 54.9 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF572 PF04502.13 CDJ47661.1 - 1.9 8.0 19.9 2.1 7.9 19.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Bud13 PF09736.9 CDJ47661.1 - 4 7.8 24.9 5.9 7.3 24.9 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Tim54 PF11711.8 CDJ47661.1 - 9.4 4.9 19.7 12 4.6 19.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Med3 PF11593.8 CDJ47662.1 - 3.2 6.9 24.0 3.6 6.7 24.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SprA-related PF12118.8 CDJ47662.1 - 3.7 6.6 26.2 4.1 6.4 26.2 1.0 1 0 0 1 1 1 0 SprA-related family Pex14_N PF04695.13 CDJ47662.1 - 5.7 7.6 22.4 7.6 7.2 22.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Period_C PF12114.8 CDJ47662.1 - 6 6.4 35.3 6.5 6.3 35.3 1.0 1 0 0 1 1 1 0 Period protein 2/3C-terminal region ASD2 PF08687.11 CDJ47662.1 - 7.2 6.1 16.9 7.8 6.0 16.9 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 CCDC106 PF15794.5 CDJ47662.1 - 9.9 5.8 27.0 14 5.3 27.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RskA PF10099.9 CDJ47663.1 - 0.00011 22.5 13.5 0.00011 22.5 13.5 8.5 3 2 3 6 6 6 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ47663.1 - 0.0006 19.5 10.2 0.0006 19.5 10.2 6.0 4 2 1 6 6 6 1 Nuclear RNA-splicing-associated protein DUF4834 PF16118.5 CDJ47663.1 - 0.0045 17.9 4.9 0.0045 17.9 4.9 7.6 4 3 2 7 7 7 1 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ47663.1 - 0.0055 16.3 29.4 0.0055 16.3 29.4 6.6 4 2 1 6 6 6 1 Spt20 family RskA PF10099.9 CDJ47664.1 - 0.012 16.0 27.3 0.012 16.0 27.3 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ47664.1 - 0.14 13.1 21.6 0.42 11.6 11.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) NEMP PF10225.9 CDJ47664.1 - 0.16 11.6 6.9 1.4 8.5 2.6 2.0 2 0 0 2 2 2 0 NEMP family PAT1 PF09770.9 CDJ47664.1 - 0.31 9.2 26.1 0.45 8.7 26.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF5327 PF17261.2 CDJ47664.1 - 0.56 11.0 22.3 0.72 10.6 9.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) SCAI PF12070.8 CDJ47664.1 - 1.3 7.8 13.9 3.6 6.3 13.7 1.7 1 1 1 2 2 2 0 Protein SCAI Connexin PF00029.19 CDJ47664.1 - 1.7 8.3 11.7 5.1 6.8 7.4 2.0 2 0 0 2 2 2 0 Connexin HA2 PF04408.23 CDJ47664.1 - 5.7 7.3 13.2 8.8 6.7 2.2 2.4 2 0 0 2 2 2 0 Helicase associated domain (HA2) RICTOR_N PF14664.6 CDJ47664.1 - 9.2 5.1 9.5 0.73 8.7 2.4 1.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term V_ATPase_I PF01496.19 CDJ47664.1 - 9.2 4.0 15.8 4.1 5.2 8.7 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Spt20 PF12090.8 CDJ47664.1 - 9.2 5.8 54.5 0.48 10.0 10.2 2.1 2 0 0 2 2 2 0 Spt20 family RskA PF10099.9 CDJ47665.1 - 0.00022 21.6 0.0 0.00065 20.0 0.0 1.7 1 1 0 1 1 1 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ47665.1 - 0.0032 17.1 6.4 0.0032 17.1 6.4 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 CDJ47665.1 - 0.0068 16.9 9.1 0.0068 16.9 9.1 3.1 3 0 0 3 3 3 1 Secretin N-terminal domain RPA43_OB PF17875.1 CDJ47665.1 - 0.0074 16.9 3.7 0.016 15.8 3.7 1.5 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I PAP_RNA-bind PF04926.15 CDJ47665.1 - 0.025 14.2 4.6 0.052 13.2 4.6 1.4 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain PPL5 PF18168.1 CDJ47665.1 - 0.027 13.8 2.0 0.053 12.8 2.0 1.4 1 0 0 1 1 1 0 Prim-pol family 5 PAT1 PF09770.9 CDJ47665.1 - 0.042 12.1 11.4 0.055 11.8 11.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4770 PF15994.5 CDJ47665.1 - 0.042 14.1 3.3 0.087 13.1 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) RR_TM4-6 PF06459.12 CDJ47665.1 - 0.082 12.7 4.0 0.13 12.1 4.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MecA PF05389.12 CDJ47665.1 - 0.09 12.4 3.5 0.19 11.3 3.2 1.6 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) TCP PF03634.13 CDJ47665.1 - 0.12 13.0 16.5 0.51 10.9 11.1 2.2 2 0 0 2 2 2 0 TCP family transcription factor Plasmodium_Vir PF05795.11 CDJ47665.1 - 0.18 11.2 2.5 0.27 10.6 2.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Otopetrin PF03189.13 CDJ47665.1 - 0.19 10.5 0.6 0.25 10.1 0.6 1.2 1 0 0 1 1 1 0 Otopetrin V_ATPase_I PF01496.19 CDJ47665.1 - 0.3 9.0 10.1 0.43 8.4 10.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ47665.1 - 0.33 10.7 2.2 0.47 10.2 2.2 1.2 1 0 0 1 1 1 0 Connexin FYDLN_acid PF09538.10 CDJ47665.1 - 0.49 11.1 4.8 1.1 10.0 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Tim54 PF11711.8 CDJ47665.1 - 0.66 8.7 7.3 1.1 8.0 7.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4175 PF13779.6 CDJ47665.1 - 0.75 7.6 14.7 1.1 7.1 14.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SelP_N PF04592.14 CDJ47665.1 - 0.92 8.9 20.4 1.4 8.3 20.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Presenilin PF01080.17 CDJ47665.1 - 1 8.1 12.1 0.35 9.6 8.2 1.8 2 0 0 2 2 2 0 Presenilin DUF4820 PF16091.5 CDJ47665.1 - 2.2 7.6 10.8 0.19 11.1 6.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) MscS_TM PF12794.7 CDJ47665.1 - 2.4 6.9 3.4 4.4 6.1 3.4 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Neur_chan_memb PF02932.16 CDJ47665.1 - 2.6 8.0 8.2 0.35 10.9 4.0 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 CDJ47665.1 - 4.8 8.2 12.8 0.99 10.4 6.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3464 PF11947.8 CDJ47665.1 - 6.1 6.6 9.2 14 5.5 9.2 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF5327 PF17261.2 CDJ47665.1 - 6.2 7.6 17.0 2 9.2 11.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5327) CPSF100_C PF13299.6 CDJ47665.1 - 7.3 6.7 7.5 1.9 8.7 4.2 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF572 PF04502.13 CDJ47667.1 - 0.00079 19.1 43.0 0.37 10.4 0.8 3.3 3 0 0 3 3 3 3 Family of unknown function (DUF572) Utp11 PF03998.13 CDJ47667.1 - 0.0033 17.4 2.1 0.0033 17.4 2.1 3.8 3 1 0 3 3 3 1 Utp11 protein Exonuc_VII_L PF02601.15 CDJ47667.1 - 0.0044 16.6 0.8 0.0044 16.6 0.8 4.1 3 1 0 3 3 3 2 Exonuclease VII, large subunit RskA PF10099.9 CDJ47667.1 - 0.26 11.6 0.0 0.18 12.1 24.2 9.4 4 2 3 7 7 7 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ47668.1 - 0.0013 18.4 24.8 0.0013 18.4 24.8 7.0 1 1 7 8 8 8 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ47668.1 - 0.0085 16.4 15.7 0.0085 16.4 15.7 10.6 4 3 6 10 10 10 1 Domain of unknown function (DUF755) TAF4 PF05236.14 CDJ47668.1 - 0.0091 15.8 22.2 0.0091 15.8 22.2 7.6 1 1 6 7 7 7 2 Transcription initiation factor TFIID component TAF4 family MAT1 PF06391.13 CDJ47671.1 - 1.2 8.9 36.8 1.6 8.5 36.8 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Macoilin PF09726.9 CDJ47671.1 - 3.1 6.2 26.3 3.4 6.1 26.3 1.0 1 0 0 1 1 1 0 Macoilin family VIT1 PF01988.19 CDJ47671.1 - 3.3 7.5 13.9 4.1 7.2 13.9 1.2 1 0 0 1 1 1 0 VIT family Activator_LAG-3 PF11498.8 CDJ47672.1 - 9.9e-07 28.1 12.5 1.5e-06 27.5 12.5 1.4 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Med15 PF09606.10 CDJ47672.1 - 0.00051 18.9 13.3 0.00051 18.9 13.3 2.2 2 1 0 2 2 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CDJ47672.1 - 0.00088 18.3 11.0 0.0012 17.8 11.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) PAT1 PF09770.9 CDJ47672.1 - 0.014 13.7 10.8 0.022 13.0 10.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1389 PF07146.11 CDJ47672.1 - 0.028 13.7 2.4 0.042 13.1 2.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1389) DDHD PF02862.17 CDJ47672.1 - 0.076 13.2 2.0 0.098 12.8 2.0 1.5 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 CDJ47672.1 - 0.085 11.6 1.9 0.094 11.5 1.9 1.2 1 0 0 1 1 1 0 Presenilin EIF4E-T PF10477.9 CDJ47672.1 - 0.086 11.7 13.8 0.13 11.1 13.8 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Nse4_C PF08743.10 CDJ47672.1 - 0.16 12.3 2.7 0.4 11.0 2.7 1.6 1 0 0 1 1 1 0 Nse4 C-terminal Neur_chan_memb PF02932.16 CDJ47672.1 - 0.24 11.4 0.8 0.35 10.9 0.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ47672.1 - 0.29 11.1 8.0 0.56 10.1 8.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 CDJ47672.1 - 0.56 9.1 7.6 0.75 8.7 7.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 CDJ47672.1 - 0.72 9.6 6.5 1.4 8.6 6.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spt20 PF12090.8 CDJ47672.1 - 4.6 6.8 31.2 9.7 5.7 31.2 1.5 1 0 0 1 1 1 0 Spt20 family MCU PF04678.13 CDJ47672.1 - 5.3 7.1 7.1 0.93 9.6 3.2 1.8 2 0 0 2 2 2 0 Mitochondrial calcium uniporter TERB2 PF15101.6 CDJ47672.1 - 7.8 6.5 12.5 14 5.6 12.5 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4834 PF16118.5 CDJ47672.1 - 9.2 7.3 9.1 19 6.3 9.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) LOH1CR12 PF10158.9 CDJ47673.1 - 0.11 12.5 3.3 0.15 12.0 3.3 1.1 1 0 0 1 1 1 0 Tumour suppressor protein PSD4 PF07631.11 CDJ47673.1 - 0.2 12.2 1.9 0.33 11.5 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) DUF2722 PF10846.8 CDJ47674.1 - 0.0017 17.4 5.9 0.0017 17.4 5.9 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) SPX PF03105.19 CDJ47674.1 - 0.004 17.1 10.2 0.004 17.1 10.2 2.1 2 0 0 2 2 2 1 SPX domain Lin-8 PF03353.15 CDJ47674.1 - 0.008 15.8 17.0 0.008 15.8 17.0 2.2 2 0 0 2 2 2 1 Ras-mediated vulval-induction antagonist SOG2 PF10428.9 CDJ47674.1 - 0.19 10.9 29.3 0.37 10.0 12.8 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein Apt1 PF10351.9 CDJ47674.1 - 0.21 10.4 19.4 0.044 12.6 4.9 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain SLC12 PF03522.15 CDJ47674.1 - 0.48 9.4 24.8 0.057 12.4 14.9 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Plasmodium_Vir PF05795.11 CDJ47674.1 - 0.69 9.3 16.0 0.28 10.6 4.0 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein MPM1 PF17234.2 CDJ47674.1 - 1 9.6 29.7 0.79 10.0 7.3 3.2 3 0 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 LMBR1 PF04791.16 CDJ47674.1 - 1.1 8.0 6.7 1.8 7.3 6.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2828 PF11443.8 CDJ47674.1 - 1.5 6.8 15.9 0.068 11.3 9.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) SOBP PF15279.6 CDJ47674.1 - 1.8 9.1 32.5 0.29 11.7 19.6 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Pinin_SDK_memA PF04696.13 CDJ47674.1 - 4 7.5 46.8 1.2 9.2 4.1 3.4 3 0 0 3 3 3 0 pinin/SDK/memA/ protein conserved region DUF4834 PF16118.5 CDJ47674.1 - 7.8 7.5 38.2 0.66 11.0 11.1 4.2 3 1 0 3 3 2 0 Domain of unknown function (DUF4834) ESM4 PF15952.5 CDJ47674.1 - 8 6.9 40.4 8.8 6.7 1.7 2.3 2 0 0 2 2 2 0 Enhancer of split M4 family SR-25 PF10500.9 CDJ47674.1 - 9.1 5.8 34.2 0.18 11.4 13.5 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF3474 PF11960.8 CDJ47675.1 - 0.5 10.6 4.0 0.57 10.4 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) FHIPEP PF00771.20 CDJ47675.1 - 1.8 7.0 12.0 2.2 6.7 12.0 1.1 1 0 0 1 1 1 0 FHIPEP family Presenilin PF01080.17 CDJ47675.1 - 3 6.5 19.5 3.2 6.4 19.5 1.0 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 CDJ47675.1 - 6.2 5.2 13.8 7.1 5.0 13.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Hydin_ADK PF17213.3 CDJ47675.1 - 6.3 7.0 15.9 7.7 6.8 15.9 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain URO-D PF01208.17 CDJ47676.1 - 5e-43 147.6 0.2 3.2e-32 112.0 0.0 2.1 1 1 1 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) PARG_cat PF05028.14 CDJ47677.1 - 9.4e-19 67.9 1.4 7.3e-17 61.7 0.1 2.5 2 0 0 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) Filament_head PF04732.14 CDJ47677.1 - 7.5 7.5 38.0 5.3 8.0 24.8 2.7 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Ribosomal_L14 PF00238.19 CDJ47679.1 - 3.4e-09 36.8 0.0 7e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e CHASE6_C PF17150.4 CDJ47679.1 - 0.41 11.4 4.2 0.62 10.8 4.2 1.2 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain MCM PF00493.23 CDJ47682.1 - 3.2e-93 310.9 0.1 4.8e-93 310.4 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CDJ47682.1 - 5.3e-26 90.9 2.8 9.7e-26 90.0 2.8 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 CDJ47682.1 - 3.6e-17 62.4 0.0 3.9e-16 59.1 0.0 2.4 2 1 0 2 2 2 1 MCM OB domain Mg_chelatase PF01078.21 CDJ47682.1 - 8e-07 28.6 0.1 4.3e-06 26.3 0.1 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ47682.1 - 0.0048 16.7 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 CDJ47682.1 - 0.022 14.9 1.1 0.051 13.8 1.1 1.5 1 0 0 1 1 1 0 Midasin AAA lid domain AAA_5 PF07728.14 CDJ47682.1 - 0.022 14.7 0.0 0.064 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PucR PF07905.11 CDJ47682.1 - 0.12 12.6 0.0 0.48 10.7 0.0 2.0 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family BAG PF02179.16 CDJ47682.1 - 4.7 7.7 7.3 0.51 10.8 0.4 2.8 3 0 0 3 3 3 0 BAG domain SR-25 PF10500.9 CDJ47683.1 - 1.1e-05 25.1 6.5 1.1e-05 25.1 6.5 3.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Transformer PF06495.11 CDJ47683.1 - 0.001 19.2 6.1 0.001 19.2 6.1 3.3 3 0 0 3 3 3 1 Fruit fly transformer protein SUIM_assoc PF16619.5 CDJ47683.1 - 0.0084 16.2 2.2 0.0084 16.2 2.2 5.4 5 1 0 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 ORC_WH_C PF18137.1 CDJ47683.1 - 0.017 15.2 2.7 0.017 15.2 2.7 3.0 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal Serglycin PF04360.12 CDJ47683.1 - 0.017 15.1 2.4 0.049 13.6 2.0 2.0 2 0 0 2 2 2 0 Serglycin DUF4834 PF16118.5 CDJ47683.1 - 0.024 15.6 17.0 2.8 9.0 0.2 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ47683.1 - 0.37 8.7 7.4 2.9 5.7 0.0 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Rsc14 PF08586.10 CDJ47683.1 - 1 10.2 3.9 0.93 10.3 0.1 2.5 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Nup54 PF13874.6 CDJ47683.1 - 1 9.5 19.5 0.031 14.4 2.6 2.6 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 DUF4407 PF14362.6 CDJ47683.1 - 3.4 6.9 21.3 0.67 9.2 13.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Hydrolase PF00702.26 CDJ47684.1 - 1.3e-11 45.2 0.4 1.7e-08 35.0 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ47684.1 - 0.00022 21.1 1.9 0.00029 20.7 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Spt20 PF12090.8 CDJ47685.1 - 0.00089 18.9 54.3 0.0029 17.2 14.2 4.8 4 1 0 4 4 3 3 Spt20 family RskA PF10099.9 CDJ47685.1 - 0.0017 18.7 15.1 0.0017 18.7 15.1 7.6 2 1 1 4 4 2 2 Anti-sigma-K factor rskA FAM76 PF16046.5 CDJ47685.1 - 0.0044 16.4 6.9 0.0044 16.4 6.9 4.2 4 0 0 4 4 4 1 FAM76 protein MMR1 PF08505.10 CDJ47685.1 - 0.011 16.0 10.9 0.011 16.0 10.9 4.6 4 1 0 4 4 3 0 Mitochondrial Myo2 receptor-related protein MecA PF05389.12 CDJ47685.1 - 0.11 12.1 22.5 0.67 9.5 3.9 4.3 4 0 0 4 4 4 0 Negative regulator of genetic competence (MecA) SpoIIP PF07454.11 CDJ47685.1 - 0.47 9.9 34.9 0.32 10.4 10.5 4.3 4 0 0 4 4 4 0 Stage II sporulation protein P (SpoIIP) PTPRCAP PF15713.5 CDJ47685.1 - 1.2 9.4 40.0 0.34 11.2 6.2 5.2 4 1 0 4 4 4 0 Protein tyrosine phosphatase receptor type C-associated Otopetrin PF03189.13 CDJ47685.1 - 1.2 7.9 14.3 0.0096 14.8 2.3 2.6 3 0 0 3 3 3 0 Otopetrin RR_TM4-6 PF06459.12 CDJ47685.1 - 1.2 8.9 32.1 0.069 13.0 5.1 4.3 4 0 0 4 4 4 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.9 CDJ47685.1 - 2.3 8.3 33.1 0.63 10.1 5.9 4.3 4 0 0 4 4 4 0 Gti1/Pac2 family Rxt3 PF08642.10 CDJ47685.1 - 2.6 8.8 23.8 0.72 10.6 6.2 4.6 4 0 0 4 4 4 0 Histone deacetylation protein Rxt3 Suf PF05843.14 CDJ47685.1 - 3.1 7.7 58.7 0.051 13.6 11.6 4.6 4 1 0 4 4 4 0 Suppressor of forked protein (Suf) GHMP_kinases_N PF00288.26 CDJ47685.1 - 4.8 7.5 0.0 4.8 7.5 0.0 10.6 7 3 3 10 10 3 0 GHMP kinases N terminal domain RPA43_OB PF17875.1 CDJ47685.1 - 6.1 7.5 26.7 2.3 8.8 3.8 4.7 5 0 0 5 5 4 0 RPA43 OB domain in RNA Pol I TFIIA PF03153.13 CDJ47688.1 - 8.1 6.3 39.2 19 5.1 39.2 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLD3 PF08639.10 CDJ47690.1 - 0.00046 19.1 2.8 0.0009 18.1 2.8 1.4 1 0 0 1 1 1 1 DNA replication regulator SLD3 Peroxin-13_N PF04088.13 CDJ47690.1 - 0.0035 17.6 2.8 0.0035 17.6 2.8 1.9 1 1 1 2 2 2 1 Peroxin 13, N-terminal region Orf78 PF06024.12 CDJ47690.1 - 0.0044 17.3 4.3 0.0044 17.3 4.3 1.9 1 1 1 2 2 2 1 Orf78 (ac78) DUF2615 PF11027.8 CDJ47690.1 - 0.19 11.9 11.2 0.54 10.4 5.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) CSG2 PF16965.5 CDJ47690.1 - 0.39 9.6 2.7 0.5 9.2 2.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Corona_NS3b PF03053.14 CDJ47690.1 - 0.41 10.4 4.8 0.59 9.8 4.8 1.2 1 0 0 1 1 1 0 ORF3b coronavirus protein Peptidase_M56 PF05569.11 CDJ47690.1 - 0.46 9.6 2.3 0.67 9.1 0.3 1.9 2 0 0 2 2 2 0 BlaR1 peptidase M56 EIIBC-GUT_N PF03612.14 CDJ47690.1 - 1.1 8.9 5.5 0.14 11.9 1.1 1.7 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2207 PF09972.9 CDJ47690.1 - 2.3 6.9 4.0 1.8 7.3 2.4 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) PigN PF04987.14 CDJ47690.1 - 3.2 6.5 8.6 4.2 6.1 8.6 1.3 1 1 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) PIP5K PF01504.18 CDJ47690.1 - 5 6.3 9.1 7.5 5.7 9.1 1.4 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase TMEM208_SND2 PF05620.11 CDJ47690.1 - 7.4 6.3 9.2 0.37 10.6 0.9 2.4 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 CAF1-p150_N PF15557.6 CDJ47691.1 - 0.048 13.6 0.3 0.091 12.7 0.3 1.4 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to PCNA NDUF_B12 PF08122.12 CDJ47691.1 - 0.071 13.2 0.5 0.23 11.5 0.3 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Adeno_PIX PF03955.14 CDJ47691.1 - 0.26 11.4 2.7 0.22 11.7 0.9 1.7 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) V_ATPase_I PF01496.19 CDJ47694.1 - 7.8 4.3 36.5 8.7 4.1 36.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RskA PF10099.9 CDJ47695.1 - 0.0019 18.5 11.7 0.0019 18.5 11.7 2.1 1 1 1 2 2 1 1 Anti-sigma-K factor rskA XRCC4 PF06632.12 CDJ47695.1 - 0.095 11.5 17.2 0.12 11.2 17.2 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Spore_coat_CotO PF14153.6 CDJ47695.1 - 0.32 10.9 20.8 0.42 10.5 20.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Suf PF05843.14 CDJ47695.1 - 0.37 10.7 20.3 0.45 10.4 20.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AAA_23 PF13476.6 CDJ47695.1 - 0.51 10.8 16.0 0.62 10.5 16.0 1.1 1 0 0 1 1 1 0 AAA domain FAM60A PF15396.6 CDJ47695.1 - 0.69 9.9 12.8 0.86 9.6 12.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 CDJ47695.1 - 0.7 8.6 21.2 0.82 8.4 21.2 1.0 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ47695.1 - 0.9 8.4 17.6 1.2 8.0 17.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SOBP PF15279.6 CDJ47695.1 - 1.3 9.6 14.6 1.5 9.4 14.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3381 PF11861.8 CDJ47695.1 - 1.9 8.2 18.9 4.2 7.2 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) MAJIN PF15077.6 CDJ47695.1 - 2.2 8.0 14.5 2.8 7.7 14.5 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF572 PF04502.13 CDJ47695.1 - 2.2 7.8 20.4 2.6 7.6 20.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hydin_ADK PF17213.3 CDJ47695.1 - 2.7 8.2 20.8 3.3 7.9 20.8 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain TFIIA PF03153.13 CDJ47695.1 - 2.9 7.8 34.5 4 7.3 34.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4551 PF15087.6 CDJ47695.1 - 3.5 6.3 15.3 4.1 6.1 15.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Velvet PF11754.8 CDJ47695.1 - 4 7.3 15.1 5.8 6.8 15.1 1.3 1 0 0 1 1 1 0 Velvet factor TMEM214 PF10151.9 CDJ47695.1 - 4.4 5.6 17.4 5.3 5.4 17.4 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator XRN_M PF17846.1 CDJ47695.1 - 5.5 5.8 13.3 6.5 5.6 13.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain NEMP PF10225.9 CDJ47695.1 - 5.7 6.5 5.0 7 6.2 5.0 1.2 1 0 0 1 1 1 0 NEMP family PBP1_TM PF14812.6 CDJ47695.1 - 6.5 7.2 10.4 0.89 10.0 4.3 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MMR1 PF08505.10 CDJ47695.1 - 7 6.9 20.5 9.9 6.4 20.5 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein ALMT PF11744.8 CDJ47695.1 - 8.1 5.1 13.7 9.8 4.9 13.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ47695.1 - 8.9 5.2 16.2 10 5.0 16.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PPL5 PF18168.1 CDJ47696.1 - 0.0012 18.2 6.3 0.0017 17.8 6.3 1.1 1 0 0 1 1 1 1 Prim-pol family 5 CCSAP PF15748.5 CDJ47696.1 - 0.0013 19.0 14.0 0.0015 18.8 14.0 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated Endostatin PF06482.11 CDJ47696.1 - 0.0018 17.8 9.0 0.0019 17.7 9.0 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin NPR3 PF03666.13 CDJ47696.1 - 0.0029 16.5 11.6 0.003 16.4 11.6 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 CDJ47696.1 - 0.0041 16.2 6.9 0.0044 16.1 6.9 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) SAPS PF04499.15 CDJ47696.1 - 0.0046 15.8 7.9 0.005 15.7 7.9 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein CPSF100_C PF13299.6 CDJ47696.1 - 0.0048 17.1 8.0 0.0075 16.5 8.0 1.4 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal DUF4175 PF13779.6 CDJ47696.1 - 0.011 13.7 34.2 0.011 13.6 34.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PIP5K PF01504.18 CDJ47696.1 - 0.011 15.0 8.2 0.013 14.8 8.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Zip PF02535.22 CDJ47696.1 - 0.013 14.7 4.7 0.017 14.4 4.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.17 CDJ47696.1 - 0.017 15.3 10.9 0.025 14.8 10.9 1.3 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.15 CDJ47696.1 - 0.018 14.0 8.0 0.021 13.8 8.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Smg8_Smg9 PF10220.9 CDJ47696.1 - 0.018 13.4 12.6 0.022 13.1 12.6 1.0 1 0 0 1 1 1 0 Smg8_Smg9 SID-1_RNA_chan PF13965.6 CDJ47696.1 - 0.021 13.3 4.2 0.022 13.2 4.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MDM10 PF12519.8 CDJ47696.1 - 0.035 13.0 10.4 0.039 12.8 10.4 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Velvet PF11754.8 CDJ47696.1 - 0.037 14.0 12.3 0.041 13.8 12.3 1.1 1 0 0 1 1 1 0 Velvet factor eIF-3_zeta PF05091.12 CDJ47696.1 - 0.056 12.4 19.2 0.061 12.3 19.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ47696.1 - 0.058 13.4 9.6 0.064 13.3 9.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2347 PF09804.9 CDJ47696.1 - 0.062 12.9 3.4 0.065 12.8 3.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) YABBY PF04690.13 CDJ47696.1 - 0.089 13.4 9.1 0.12 13.0 9.1 1.2 1 0 0 1 1 1 0 YABBY protein PA26 PF04636.13 CDJ47696.1 - 0.1 11.5 10.2 0.12 11.3 10.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CSG2 PF16965.5 CDJ47696.1 - 0.11 11.4 5.7 0.12 11.2 5.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Ureide_permease PF07168.11 CDJ47696.1 - 0.13 10.9 5.6 0.18 10.5 5.6 1.2 1 0 0 1 1 1 0 Ureide permease DUF908 PF06012.12 CDJ47696.1 - 0.16 11.4 10.3 0.18 11.2 10.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) CLN3 PF02487.17 CDJ47696.1 - 0.17 10.9 11.8 0.22 10.5 11.8 1.1 1 0 0 1 1 1 0 CLN3 protein Cellulose_synt PF03552.14 CDJ47696.1 - 0.2 10.1 5.5 0.23 9.9 5.5 1.1 1 0 0 1 1 1 0 Cellulose synthase Peroxin-3 PF04882.12 CDJ47696.1 - 0.21 10.5 17.0 0.26 10.3 17.0 1.0 1 0 0 1 1 1 0 Peroxin-3 CBP_BcsG PF11658.8 CDJ47696.1 - 0.24 9.7 9.2 0.31 9.4 9.2 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG OATP PF03137.20 CDJ47696.1 - 0.4 8.9 5.3 0.66 8.2 5.3 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Afi1 PF07792.12 CDJ47696.1 - 0.5 10.8 22.0 0.77 10.2 22.0 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.14 CDJ47696.1 - 0.54 8.5 17.8 0.68 8.2 17.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Otopetrin PF03189.13 CDJ47696.1 - 0.79 8.5 8.3 1.1 8.0 8.3 1.1 1 0 0 1 1 1 0 Otopetrin SpoIIP PF07454.11 CDJ47696.1 - 1 8.8 24.0 1.4 8.4 24.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Rrn6 PF10214.9 CDJ47696.1 - 1.2 7.6 21.6 1.4 7.3 21.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Mem_trans PF03547.18 CDJ47696.1 - 1.3 7.3 4.0 1.6 7.1 4.0 1.1 1 0 0 1 1 1 0 Membrane transport protein STAC2_u1 PF16664.5 CDJ47696.1 - 1.6 9.2 16.6 2.7 8.5 16.6 1.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF2407_C PF13373.6 CDJ47696.1 - 2.6 8.2 14.6 54 3.9 0.0 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF5308 PF17233.2 CDJ47696.1 - 3 8.1 16.0 5.9 7.1 16.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) SLC12 PF03522.15 CDJ47696.1 - 3.6 6.5 21.4 1.3 7.9 19.2 1.3 2 0 0 2 2 2 0 Solute carrier family 12 LMBR1 PF04791.16 CDJ47696.1 - 4.2 6.2 8.6 4.7 6.0 8.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein BORG_CEP PF14957.6 CDJ47696.1 - 4.4 8.5 14.3 7.6 7.7 14.3 1.4 1 0 0 1 1 1 0 Cdc42 effector Peptidase_U57 PF05582.12 CDJ47696.1 - 6.4 6.0 15.6 9.2 5.4 15.6 1.2 1 0 0 1 1 1 0 YabG peptidase U57 FAM60A PF15396.6 CDJ47696.1 - 6.7 6.7 17.5 11 5.9 17.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Mito_carr PF00153.27 CDJ47697.1 - 4.8e-47 157.8 0.3 1.8e-18 66.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2722 PF10846.8 CDJ47698.1 - 0.0012 17.9 2.6 0.0012 17.9 2.6 14.0 10 2 3 13 13 13 4 Protein of unknown function (DUF2722) EcsB PF05975.12 CDJ47698.1 - 0.2 10.5 0.0 0.48 9.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB OTU PF02338.19 CDJ47700.1 - 1.3e-07 32.2 0.0 2.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Syntaphilin PF15290.6 CDJ47700.1 - 0.0039 16.9 3.7 0.0039 16.9 3.7 6.4 5 1 0 6 6 6 1 Golgi-localised syntaxin-1-binding clamp SID-1_RNA_chan PF13965.6 CDJ47701.1 - 1 7.7 2.7 1.5 7.2 2.6 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 ATG7_N PF16420.5 CDJ47702.1 - 1.3e-18 67.7 16.1 2e-12 47.4 9.5 5.8 3 2 2 5 5 5 2 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus SR-25 PF10500.9 CDJ47702.1 - 0.0013 18.3 7.5 0.0013 18.3 7.5 5.6 5 1 0 5 5 5 2 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 CDJ47703.1 - 0.00075 17.7 9.5 0.00095 17.4 9.5 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen SR-25 PF10500.9 CDJ47703.1 - 0.0072 16.0 8.9 0.0072 16.0 8.9 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SLC12 PF03522.15 CDJ47703.1 - 3.9 6.4 9.9 1.8 7.5 5.4 1.9 2 0 0 2 2 2 0 Solute carrier family 12 RNA_pol_Rbc25 PF08292.12 CDJ47703.1 - 4.5 7.5 12.6 3.2 8.0 0.5 3.1 3 0 0 3 3 3 0 RNA polymerase III subunit Rpc25 Velvet PF11754.8 CDJ47703.1 - 6.5 6.6 19.1 1 9.2 12.5 2.0 1 1 1 2 2 2 0 Velvet factor DUF3295 PF11702.8 CDJ47703.1 - 10 5.4 23.2 2.5 7.3 17.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) DEAD PF00270.29 CDJ47705.1 - 5.7e-23 81.6 1.1 9.5e-23 80.9 0.0 1.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase Lin-8 PF03353.15 CDJ47705.1 - 0.0014 18.3 9.0 0.0018 17.9 9.0 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist SecA_DEAD PF07517.14 CDJ47705.1 - 0.016 14.5 2.1 0.026 13.8 2.1 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain PDEase_I PF00233.19 CDJ47705.1 - 0.093 12.4 3.1 0.13 12.0 3.1 1.2 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase DUF4667 PF15700.5 CDJ47705.1 - 0.15 12.2 13.4 0.092 12.8 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) MRP-S31 PF15433.6 CDJ47705.1 - 0.16 11.6 10.0 0.2 11.3 10.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Rtt102p PF09510.10 CDJ47705.1 - 0.54 10.5 4.4 3.6 7.8 4.9 2.0 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein GREB1 PF15782.5 CDJ47705.1 - 1.1 6.3 16.3 1.3 6.0 16.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 CDJ47705.1 - 1.4 7.5 12.4 1.6 7.3 12.4 1.1 1 0 0 1 1 1 0 Hamartin protein ResIII PF04851.15 CDJ47705.1 - 2.3 8.2 7.2 0.13 12.3 0.5 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF2489 PF10675.9 CDJ47705.1 - 2.5 8.0 18.1 3.3 7.7 6.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Herpes_pp85 PF04637.12 CDJ47705.1 - 3.3 6.0 6.6 5.3 5.3 6.6 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PAT1 PF09770.9 CDJ47705.1 - 4.5 5.4 19.2 5.1 5.2 19.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3381 PF11861.8 CDJ47705.1 - 5 6.9 12.6 8 6.2 12.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Rpp20 PF12328.8 CDJ47705.1 - 8.3 6.4 12.6 1.3 8.9 2.2 2.2 1 1 1 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P MRP-S26 PF14943.6 CDJ47705.1 - 8.9 6.2 12.9 14 5.6 12.9 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DNA_pol_A_exo1 PF01612.20 CDJ47706.1 - 6.9e-14 51.9 0.0 9.9e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease RAP1 PF07218.11 CDJ47707.1 - 0.4 8.9 12.3 0.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Spt20 PF12090.8 CDJ47708.1 - 0.00025 20.8 12.0 0.00025 20.8 12.0 1.1 1 0 0 1 1 1 1 Spt20 family PAP2 PF01569.21 CDJ47708.1 - 0.00037 20.3 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 PAP2 superfamily DUF2722 PF10846.8 CDJ47708.1 - 0.00087 18.4 7.9 0.00087 18.4 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) SseC PF04888.12 CDJ47708.1 - 0.01 15.4 22.4 0.015 14.9 22.4 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family TFIIA PF03153.13 CDJ47708.1 - 0.026 14.6 16.6 0.03 14.3 16.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ47708.1 - 0.11 13.5 6.2 0.15 13.0 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Activator_LAG-3 PF11498.8 CDJ47708.1 - 0.27 10.2 18.9 0.3 10.0 18.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RIFIN PF02009.16 CDJ47708.1 - 0.5 10.2 6.4 0.7 9.7 6.4 1.2 1 0 0 1 1 1 0 Rifin UPF0560 PF10577.9 CDJ47708.1 - 0.59 8.6 6.8 0.59 8.6 6.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Suf PF05843.14 CDJ47708.1 - 0.76 9.7 5.2 0.66 9.9 5.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ47708.1 - 1.1 7.9 5.6 1.1 7.9 5.6 1.1 1 0 0 1 1 1 0 Presenilin Tic110 PF16940.5 CDJ47708.1 - 1.1 7.6 19.2 1.2 7.5 19.2 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Neur_chan_memb PF02932.16 CDJ47708.1 - 1.1 9.2 3.5 1.2 9.2 3.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 CDJ47708.1 - 1.2 8.1 7.4 1.1 8.1 7.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Roughex PF06020.11 CDJ47708.1 - 1.2 8.1 9.1 1.4 8.0 9.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein WES_acyltransf PF03007.16 CDJ47708.1 - 2.1 8.1 9.5 2.5 7.8 9.5 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain RR_TM4-6 PF06459.12 CDJ47708.1 - 2.4 7.9 5.7 2.7 7.8 5.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RLL PF10036.9 CDJ47708.1 - 2.7 7.8 10.3 3.3 7.5 10.3 1.1 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein BAF1_ABF1 PF04684.13 CDJ47708.1 - 7.6 5.5 11.6 9.5 5.1 11.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ndc1_Nup PF09531.10 CDJ47708.1 - 8.4 4.9 9.1 9.3 4.8 9.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 CDJ47708.1 - 8.8 4.8 11.9 11 4.5 11.9 1.1 1 0 0 1 1 1 0 Macoilin family SNF2_N PF00176.23 CDJ47709.1 - 8.5e-07 28.0 0.0 0.0011 17.8 0.0 2.6 2 1 0 2 2 2 2 SNF2 family N-terminal domain Spt20 PF12090.8 CDJ47709.1 - 0.00064 19.4 14.7 0.00064 19.4 14.7 3.1 3 0 0 3 3 3 1 Spt20 family Med15 PF09606.10 CDJ47709.1 - 0.0025 16.6 7.8 0.0025 16.6 7.8 3.3 3 1 0 3 3 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CDJ47709.1 - 0.0045 16.0 13.5 0.0045 16.0 13.5 2.5 4 0 0 4 4 3 1 Protein of unknown function (DUF2722) DUF1645 PF07816.11 CDJ47709.1 - 0.058 14.0 34.5 1.2 9.7 7.3 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1645) eIF-3_zeta PF05091.12 CDJ47709.1 - 0.11 11.4 3.7 0.17 10.8 3.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GSH-S_N PF02951.14 CDJ47709.1 - 0.12 12.5 0.0 1.5 9.0 0.0 2.5 1 1 1 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain SAPS PF04499.15 CDJ47709.1 - 0.61 8.8 4.5 2 7.1 4.4 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Band_3_cyto PF07565.13 CDJ47709.1 - 1 9.1 5.9 2.3 8.0 5.1 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Suf PF05843.14 CDJ47709.1 - 2.2 8.2 11.8 0.21 11.6 6.6 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Raftlin PF15250.6 CDJ47709.1 - 4.3 6.0 12.7 4.7 5.8 9.1 2.3 2 0 0 2 2 2 0 Raftlin RNA_pol_Rbc25 PF08292.12 CDJ47709.1 - 4.3 7.6 7.4 0.63 10.3 1.3 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 SLC12 PF03522.15 CDJ47709.1 - 8.9 5.2 9.0 17 4.3 9.0 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ47709.1 - 9.2 4.9 13.9 1.9 7.2 9.8 2.0 2 0 0 2 2 2 0 Presenilin TFIIF_alpha PF05793.12 CDJ47710.1 - 0.062 11.9 20.3 0.1 11.2 20.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GREB1 PF15782.5 CDJ47710.1 - 0.17 8.9 13.0 0.32 8.1 13.0 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer U79_P34 PF03064.16 CDJ47710.1 - 5.9 6.2 10.5 12 5.1 10.5 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ESM4 PF15952.5 CDJ47711.1 - 4.5 7.7 47.5 0.29 11.5 11.7 2.7 2 0 0 2 2 2 0 Enhancer of split M4 family SR-25 PF10500.9 CDJ47712.1 - 0.0027 17.3 25.3 0.0031 17.1 25.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ47712.1 - 0.0034 15.6 28.6 0.0035 15.5 28.6 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Chorion_2 PF03964.15 CDJ47712.1 - 0.068 14.0 12.3 0.093 13.6 12.3 1.2 1 0 0 1 1 1 0 Chorion family 2 Spt20 PF12090.8 CDJ47712.1 - 0.46 10.0 38.3 0.66 9.5 38.3 1.2 1 0 0 1 1 1 0 Spt20 family SPX PF03105.19 CDJ47712.1 - 0.49 10.3 17.8 0.66 9.8 17.8 1.2 1 0 0 1 1 1 0 SPX domain Cwf_Cwc_15 PF04889.12 CDJ47712.1 - 0.75 9.5 14.2 0.87 9.3 14.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CCDC24 PF15669.5 CDJ47712.1 - 1.6 8.5 17.5 1.9 8.3 17.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF1645 PF07816.11 CDJ47712.1 - 2.1 8.9 16.5 2.8 8.5 16.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Macoilin PF09726.9 CDJ47712.1 - 2.6 6.5 23.1 2.6 6.5 23.1 1.0 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 CDJ47712.1 - 2.7 7.5 25.4 2.7 7.5 25.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDK2AP PF09806.9 CDJ47712.1 - 3.4 7.7 19.2 4 7.4 19.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein ANAPC1 PF12859.7 CDJ47712.1 - 3.6 8.2 21.9 3.8 8.1 21.9 1.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 RAP1 PF07218.11 CDJ47712.1 - 4.1 5.6 10.4 3.6 5.7 10.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Paf1 PF03985.13 CDJ47712.1 - 4.7 6.1 17.7 5.1 6.0 17.7 1.0 1 0 0 1 1 1 0 Paf1 Kinesin_assoc PF16183.5 CDJ47712.1 - 4.7 7.3 8.9 5.1 7.2 8.9 1.1 1 0 0 1 1 1 0 Kinesin-associated GREB1 PF15782.5 CDJ47712.1 - 6.4 3.8 24.6 6.4 3.7 24.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CDJ47712.1 - 7.7 5.8 15.5 8.5 5.7 15.5 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MPM1 PF17234.2 CDJ47712.1 - 8.8 6.6 17.9 10 6.3 17.9 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 SDP_N PF12278.8 CDJ47712.1 - 8.9 6.4 21.5 11 6.2 21.5 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal V_ATPase_I PF01496.19 CDJ47716.1 - 0.0082 14.1 16.8 0.0097 13.9 16.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Peptidase_S49_N PF08496.10 CDJ47716.1 - 0.025 14.7 13.4 0.026 14.6 13.4 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SARAF PF06682.12 CDJ47716.1 - 0.033 13.9 13.9 0.034 13.8 13.9 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CBP_BcsG PF11658.8 CDJ47716.1 - 0.1 11.0 12.1 0.11 10.9 12.1 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG CLN3 PF02487.17 CDJ47716.1 - 0.13 11.3 11.9 0.15 11.0 11.9 1.0 1 0 0 1 1 1 0 CLN3 protein SID-1_RNA_chan PF13965.6 CDJ47716.1 - 0.14 10.5 5.7 0.15 10.4 5.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1168 PF06658.12 CDJ47716.1 - 0.16 11.8 22.4 0.18 11.6 22.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Connexin PF00029.19 CDJ47716.1 - 0.17 11.6 12.0 0.19 11.5 12.0 1.1 1 0 0 1 1 1 0 Connexin DUF2828 PF11443.8 CDJ47716.1 - 0.23 9.5 16.5 0.26 9.3 16.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ47716.1 - 0.25 10.1 20.4 0.25 10.1 20.4 1.1 1 0 0 1 1 1 0 Presenilin DUF1180 PF06679.12 CDJ47716.1 - 0.29 11.5 6.8 0.36 11.2 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CSG2 PF16965.5 CDJ47716.1 - 0.36 9.7 8.1 0.38 9.7 8.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator CCDC53 PF10152.9 CDJ47716.1 - 0.39 11.1 19.6 0.44 11.0 19.6 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Velvet PF11754.8 CDJ47716.1 - 0.42 10.5 17.4 0.47 10.3 17.4 1.0 1 0 0 1 1 1 0 Velvet factor CPSF100_C PF13299.6 CDJ47716.1 - 0.47 10.6 10.4 0.6 10.3 10.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NicO PF03824.16 CDJ47716.1 - 0.56 9.5 2.9 0.61 9.4 2.9 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Folate_carrier PF01770.18 CDJ47716.1 - 0.58 8.8 7.2 0.63 8.7 7.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier Membralin PF09746.9 CDJ47716.1 - 0.67 8.9 12.3 0.77 8.7 12.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein Baculo_PP31 PF05311.11 CDJ47716.1 - 0.85 9.1 14.5 0.99 8.8 14.5 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SLC12 PF03522.15 CDJ47716.1 - 0.91 8.5 16.9 0.92 8.5 16.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4446 PF14584.6 CDJ47716.1 - 1 9.4 7.0 1.2 9.1 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) SpoIIP PF07454.11 CDJ47716.1 - 1 8.8 17.8 1.2 8.6 17.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Ctr PF04145.15 CDJ47716.1 - 1 9.9 9.2 1.3 9.6 9.2 1.2 1 0 0 1 1 1 0 Ctr copper transporter family PIP5K PF01504.18 CDJ47716.1 - 1.1 8.4 15.1 1.3 8.2 15.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase BORG_CEP PF14957.6 CDJ47716.1 - 1.2 10.3 11.1 1.3 10.2 11.1 1.1 1 0 0 1 1 1 0 Cdc42 effector Serinc PF03348.15 CDJ47716.1 - 1.5 7.7 8.1 1.6 7.6 8.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) OATP PF03137.20 CDJ47716.1 - 1.5 7.0 6.6 2 6.6 6.6 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CobT PF06213.12 CDJ47716.1 - 1.7 8.0 24.8 1.9 7.8 24.8 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pex14_N PF04695.13 CDJ47716.1 - 2.1 9.0 30.8 2.7 8.7 30.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Scs3p PF10261.9 CDJ47716.1 - 3 7.3 5.4 3.8 6.9 5.4 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM YABBY PF04690.13 CDJ47716.1 - 3.5 8.2 15.7 4.3 7.9 15.7 1.1 1 0 0 1 1 1 0 YABBY protein Otopetrin PF03189.13 CDJ47716.1 - 4 6.1 10.1 4.5 6.0 10.1 1.1 1 0 0 1 1 1 0 Otopetrin RR_TM4-6 PF06459.12 CDJ47716.1 - 4 7.2 19.5 4.2 7.1 19.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ47716.1 - 4.1 7.4 16.6 4.3 7.3 16.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HGTP_anticodon2 PF12745.7 CDJ47716.1 - 4.3 6.8 17.7 5.4 6.4 17.7 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs NEMP PF10225.9 CDJ47716.1 - 4.5 6.9 8.4 5.4 6.6 8.4 1.1 1 0 0 1 1 1 0 NEMP family DUF4746 PF15928.5 CDJ47716.1 - 4.6 6.6 12.6 4.8 6.5 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SelP_N PF04592.14 CDJ47716.1 - 4.8 6.5 22.4 5.2 6.4 22.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ALMT PF11744.8 CDJ47716.1 - 4.9 5.9 16.2 5.2 5.8 16.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2464 PF10240.9 CDJ47716.1 - 5.7 6.4 14.2 6.3 6.3 14.2 1.0 1 0 0 1 1 1 0 Multivesicular body subunit 12 Zip PF02535.22 CDJ47716.1 - 8 5.6 10.3 8.1 5.6 10.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.17 CDJ47716.1 - 8.3 6.5 15.3 12 6.0 15.3 1.3 1 0 0 1 1 1 0 DDHD domain Gti1_Pac2 PF09729.9 CDJ47716.1 - 8.5 6.4 16.9 10 6.2 16.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Dicty_REP PF05086.12 CDJ47716.1 - 9.1 4.1 12.5 8.3 4.2 12.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Endostatin PF06482.11 CDJ47716.1 - 9.2 5.6 19.9 9.5 5.6 19.9 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin FAM60A PF15396.6 CDJ47716.1 - 9.3 6.2 15.4 11 6.0 15.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A O-antigen_lig PF13425.6 CDJ47716.1 - 9.7 4.8 9.0 11 4.7 9.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Hid1 PF12722.7 CDJ47716.1 - 9.8 4.2 17.6 11 4.0 17.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM176 PF14851.6 CDJ47717.1 - 0.034 13.8 4.0 0.035 13.8 4.0 1.0 1 0 0 1 1 1 0 FAM176 family Spt20 PF12090.8 CDJ47717.1 - 0.045 13.4 24.6 0.046 13.3 24.6 1.2 1 0 0 1 1 1 0 Spt20 family MecA PF05389.12 CDJ47717.1 - 0.055 13.1 8.4 0.058 13.0 8.4 1.0 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF2722 PF10846.8 CDJ47717.1 - 0.063 12.2 20.7 0.059 12.3 20.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Orf78 PF06024.12 CDJ47717.1 - 0.065 13.5 5.6 0.08 13.2 5.6 1.1 1 0 0 1 1 1 0 Orf78 (ac78) Nup192 PF11894.8 CDJ47717.1 - 0.069 10.3 9.4 0.078 10.1 9.4 1.0 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 Pex14_N PF04695.13 CDJ47717.1 - 0.096 13.3 10.7 0.1 13.2 10.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glt_symporter PF03616.14 CDJ47717.1 - 0.11 11.1 4.2 0.11 11.1 4.2 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF4457 PF14652.6 CDJ47717.1 - 0.13 11.4 7.6 0.14 11.4 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) Tsg PF04668.12 CDJ47717.1 - 0.13 12.9 4.2 0.14 12.9 4.2 1.1 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region DUF2370 PF10176.9 CDJ47717.1 - 0.16 11.6 3.3 0.18 11.5 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) SpoIIP PF07454.11 CDJ47717.1 - 0.17 11.3 6.0 0.18 11.3 6.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Suf PF05843.14 CDJ47717.1 - 0.21 11.5 12.5 0.21 11.5 12.5 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDC24_OB1 PF17246.2 CDJ47717.1 - 0.24 11.5 4.5 0.26 11.4 4.5 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 1 EIIBC-GUT_N PF03612.14 CDJ47717.1 - 0.24 11.1 7.1 0.24 11.1 7.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 CDJ47717.1 - 0.32 9.7 6.1 0.34 9.6 6.1 1.2 1 0 0 1 1 1 0 Presenilin DcuA_DcuB PF03605.14 CDJ47717.1 - 0.37 9.6 2.6 0.39 9.6 2.6 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF3464 PF11947.8 CDJ47717.1 - 0.54 10.0 6.3 0.62 9.8 6.3 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TFIIA PF03153.13 CDJ47717.1 - 0.54 10.2 22.8 0.49 10.3 22.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CSG2 PF16965.5 CDJ47717.1 - 0.58 9.1 3.6 0.56 9.1 3.6 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator DcuC PF03606.15 CDJ47717.1 - 0.92 7.9 3.1 0.97 7.8 3.1 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier TERB2 PF15101.6 CDJ47717.1 - 0.96 9.5 11.7 0.94 9.5 11.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4175 PF13779.6 CDJ47717.1 - 1 7.2 19.4 0.94 7.3 19.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PigN PF04987.14 CDJ47717.1 - 1.3 7.8 7.3 1.4 7.7 7.3 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Zip PF02535.22 CDJ47717.1 - 1.4 8.1 4.2 1.5 7.9 4.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Folate_carrier PF01770.18 CDJ47717.1 - 1.5 7.5 6.4 1.6 7.4 6.4 1.0 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.20 CDJ47717.1 - 1.7 6.9 5.4 1.7 6.9 5.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Corona_NS3b PF03053.14 CDJ47717.1 - 1.7 8.3 4.0 2 8.1 4.0 1.0 1 0 0 1 1 1 0 ORF3b coronavirus protein PEX11 PF05648.14 CDJ47717.1 - 1.8 8.0 6.8 1.8 8.0 6.8 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Pex26 PF07163.12 CDJ47717.1 - 1.9 7.8 11.8 1.8 7.8 11.8 1.0 1 0 0 1 1 1 0 Pex26 protein WBP-1 PF11669.8 CDJ47717.1 - 1.9 9.2 6.2 2.1 9.0 6.2 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 Med15 PF09606.10 CDJ47717.1 - 3 6.4 25.2 2.8 6.5 25.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RED_N PF07808.13 CDJ47717.1 - 3.3 7.2 12.7 3.3 7.2 12.7 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region FHIPEP PF00771.20 CDJ47717.1 - 3.5 6.0 9.2 3.4 6.0 9.2 1.0 1 0 0 1 1 1 0 FHIPEP family MDM10 PF12519.8 CDJ47717.1 - 4 6.2 10.7 4.5 6.0 10.7 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF3371 PF11851.8 CDJ47717.1 - 4.2 8.5 12.8 4.3 8.4 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) CLN3 PF02487.17 CDJ47717.1 - 4.7 6.1 6.6 4.3 6.3 6.6 1.0 1 0 0 1 1 1 0 CLN3 protein dsDNA_bind PF01984.20 CDJ47717.1 - 5.5 7.3 25.4 2.4 8.5 23.4 1.4 2 0 0 2 2 1 0 Double-stranded DNA-binding domain UPF0560 PF10577.9 CDJ47717.1 - 6 5.2 13.8 5.1 5.5 13.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Rpp20 PF12328.8 CDJ47717.1 - 6.7 6.7 13.2 7.9 6.4 13.2 1.3 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P USP8_interact PF08941.10 CDJ47717.1 - 7.7 6.3 15.3 8.1 6.2 15.3 1.0 1 0 0 1 1 1 0 USP8 interacting RskA PF10099.9 CDJ47718.1 - 0.00017 21.9 6.3 0.00017 21.9 6.3 2.5 3 0 0 3 3 3 2 Anti-sigma-K factor rskA Acetyltransf_1 PF00583.25 CDJ47718.1 - 0.0035 17.6 0.1 1.8 8.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family PI3K_1B_p101 PF10486.9 CDJ47718.1 - 0.023 12.5 24.3 0.034 11.9 24.3 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Tyrosinase PF00264.20 CDJ47718.1 - 0.24 11.7 2.0 0.41 10.9 2.0 1.4 1 0 0 1 1 1 0 Common central domain of tyrosinase SLC12 PF03522.15 CDJ47718.1 - 1.3 7.9 9.3 1.8 7.5 9.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 TFIIA PF03153.13 CDJ47718.1 - 1.5 8.7 20.7 0.37 10.7 16.2 1.7 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit rve PF00665.26 CDJ47720.1 - 3.9e-14 52.9 0.0 1.1e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ47720.1 - 9.8e-14 51.2 0.7 3.2e-13 49.5 0.7 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 CDJ47720.1 - 1.4e-08 35.2 0.0 3.6e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDJ47720.1 - 3.7e-08 33.2 0.0 7.1e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 CDJ47720.1 - 1.7e-07 31.5 0.0 3.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDJ47720.1 - 4e-07 30.5 0.0 9.7e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 CDJ47720.1 - 0.0007 19.2 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 CDJ47720.1 - 0.027 14.7 0.4 0.077 13.2 0.4 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 CDJ47720.1 - 0.05 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ47720.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease rve_3 PF13683.6 CDJ47720.1 - 0.11 12.3 0.2 4.8 7.0 0.1 2.6 2 0 0 2 2 2 0 Integrase core domain SNF2_N PF00176.23 CDJ47721.1 - 1.4e-19 70.1 0.0 1.4e-18 66.8 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 CDJ47721.1 - 9.4e-05 22.5 0.0 0.00033 20.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ47721.1 - 0.026 14.3 0.0 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF4658 PF15555.6 CDJ47722.1 - 0.49 10.5 4.8 0.96 9.6 4.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) DUF4554 PF15091.6 CDJ47722.1 - 3.1 6.6 6.7 4.3 6.1 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) PNTB PF02233.16 CDJ47725.1 - 1.7e-135 452.5 24.7 1.8e-86 290.9 2.2 2.4 1 1 1 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 CDJ47725.1 - 2.5e-66 223.0 1.5 3.6e-66 222.5 0.6 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CDJ47725.1 - 6.2e-30 104.3 0.0 1.4e-29 103.2 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 CDJ47725.1 - 5.4e-06 25.9 0.1 0.065 12.6 0.2 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 CDJ47725.1 - 0.0057 16.4 0.6 0.15 11.8 0.2 3.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Tti2 PF10521.9 CDJ47726.1 - 0.00033 20.3 0.0 0.001 18.7 0.0 1.8 1 0 0 1 1 1 1 Tti2 family AAA_11 PF13086.6 CDJ47727.1 - 5.5e-57 193.5 0.0 2.7e-29 102.8 0.9 3.0 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 CDJ47727.1 - 5.2e-56 189.4 0.0 7.9e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ47727.1 - 9.5e-11 42.2 0.1 0.00011 22.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CDJ47727.1 - 7.8e-10 38.8 2.8 0.00036 20.3 1.0 3.2 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CDJ47727.1 - 0.0008 19.2 0.2 0.042 13.6 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CDJ47727.1 - 0.02 14.4 0.7 2.7 7.4 0.1 3.3 3 1 1 4 4 4 0 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 CDJ47727.1 - 0.077 12.8 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_29 PF13555.6 CDJ47727.1 - 0.11 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CDJ47727.1 - 0.11 12.8 0.1 0.46 10.8 0.1 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CDJ47727.1 - 0.14 12.6 0.1 0.27 11.6 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0181 PF03701.14 CDJ47728.1 - 0.034 13.8 0.2 4 7.2 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) RRM_1 PF00076.22 CDJ47729.1 - 8e-37 124.9 0.2 8e-14 51.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CDJ47729.1 - 6.9e-06 27.1 0.3 6.9e-06 27.1 0.3 2.7 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 CDJ47729.1 - 2.7e-05 23.9 0.0 0.14 12.1 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif DUF1866 PF08952.11 CDJ47729.1 - 0.016 15.0 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) RRM_3 PF08777.11 CDJ47729.1 - 0.02 15.0 0.0 4.7 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA binding motif DbpA PF03880.15 CDJ47729.1 - 0.25 11.3 1.0 28 4.8 0.0 3.4 4 0 0 4 4 4 0 DbpA RNA binding domain PIP5K PF01504.18 CDJ47730.1 - 1.2e-77 260.8 0.1 2.6e-77 259.7 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Med3 PF11593.8 CDJ47731.1 - 0.00068 19.0 22.7 0.00085 18.6 22.7 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal TFIIA PF03153.13 CDJ47731.1 - 0.0009 19.3 16.3 0.00094 19.3 16.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ47731.1 - 0.0029 16.6 11.1 0.0029 16.6 11.1 1.4 2 0 0 2 2 1 1 Protein of unknown function (DUF2722) FAM199X PF15814.5 CDJ47731.1 - 0.012 14.7 2.7 0.017 14.2 2.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X FHIPEP PF00771.20 CDJ47731.1 - 0.013 14.0 1.6 0.014 13.9 1.6 1.1 1 0 0 1 1 1 0 FHIPEP family Suf PF05843.14 CDJ47731.1 - 0.023 14.7 5.7 0.026 14.5 5.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) VIR_N PF15912.5 CDJ47731.1 - 0.031 13.9 1.7 0.042 13.4 1.7 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Spt20 PF12090.8 CDJ47731.1 - 0.36 10.4 20.8 0.69 9.5 20.8 1.5 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 CDJ47731.1 - 0.39 8.9 13.4 0.41 8.9 13.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 CDJ47731.1 - 0.4 9.3 4.0 0.42 9.3 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 CDJ47731.1 - 0.4 10.7 1.6 0.44 10.6 1.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ47731.1 - 1.3 7.7 5.5 1.6 7.4 5.5 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ47731.1 - 1.5 9.8 7.9 2.9 8.9 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MSP1_C PF07462.11 CDJ47731.1 - 2.7 6.6 6.2 3.3 6.3 6.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Peptidase_S15 PF02129.18 CDJ47731.1 - 3.2 7.3 8.8 4.6 6.7 8.8 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DivIC PF04977.15 CDJ47731.1 - 4.8 7.0 13.4 10 6.0 13.4 1.5 1 0 0 1 1 1 0 Septum formation initiator MSP1_C PF07462.11 CDJ47732.1 - 0.0074 15.0 0.9 0.0074 15.0 0.9 2.9 3 0 0 3 3 3 1 Merozoite surface protein 1 (MSP1) C-terminus CDH1_2_SANT_HL1 PF18375.1 CDJ47732.1 - 0.079 13.6 0.2 0.079 13.6 0.2 4.3 5 1 0 5 5 5 0 CDH1/2 SANT-Helical linker 1 Peptidase_M16 PF00675.20 CDJ47732.1 - 0.21 11.6 0.0 0.21 11.6 0.0 3.0 4 0 0 4 4 4 0 Insulinase (Peptidase family M16) PRIMA1 PF16101.5 CDJ47732.1 - 0.77 9.8 5.5 0.77 9.8 3.3 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Helicase_C PF00271.31 CDJ47733.1 - 3.9e-19 69.0 0.0 8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ47733.1 - 9.7e-13 48.3 0.0 1.8e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SPX PF03105.19 CDJ47733.1 - 0.88 9.4 3.1 1.2 8.9 3.1 1.2 1 0 0 1 1 1 0 SPX domain Rotamase_2 PF13145.6 CDJ47733.1 - 4.4 8.2 9.6 1.7 9.5 0.3 2.7 3 0 0 3 3 3 0 PPIC-type PPIASE domain Cnd2 PF05786.14 CDJ47735.1 - 4.7e-09 35.5 0.3 4.7e-09 35.5 0.3 4.6 2 2 1 4 4 4 1 Condensin complex subunit 2 DUF2722 PF10846.8 CDJ47735.1 - 2.6e-05 23.4 13.5 0.00065 18.8 0.4 5.6 3 1 2 5 5 5 2 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ47735.1 - 0.014 16.1 6.6 0.014 16.1 6.6 6.5 4 1 1 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4179 PF13786.6 CDJ47736.1 - 2.5 8.6 0.0 2.5 8.6 0.0 5.4 5 1 0 5 5 5 0 Domain of unknown function (DUF4179) SR-25 PF10500.9 CDJ47736.1 - 4.2 6.9 27.8 3.9 7.0 2.8 4.1 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein Baculo_PP31 PF05311.11 CDJ47736.1 - 8.4 5.8 21.6 0.57 9.6 1.6 2.8 3 0 0 3 3 3 0 Baculovirus 33KDa late protein (PP31) DUF2722 PF10846.8 CDJ47737.1 - 0.0011 18.0 1.8 0.07 12.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ47737.1 - 7.2 6.1 21.5 0.47 10.0 0.3 2.2 2 0 0 2 2 2 0 Spt20 family G0-G1_switch_2 PF15103.6 CDJ47738.1 - 0.25 11.8 9.8 0.27 11.7 9.8 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF2722 PF10846.8 CDJ47738.1 - 0.89 8.4 29.7 0.98 8.3 29.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SpoIIP PF07454.11 CDJ47738.1 - 1.2 8.5 10.3 1.3 8.4 10.3 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Spt20 PF12090.8 CDJ47738.1 - 1.7 8.2 34.9 1.9 8.0 34.9 1.1 1 0 0 1 1 1 0 Spt20 family TERB2 PF15101.6 CDJ47738.1 - 1.7 8.6 14.9 1.7 8.6 14.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 CDJ47738.1 - 2 7.1 12.2 2.1 7.0 12.2 1.0 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ47738.1 - 2.1 9.3 14.8 2.4 9.2 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RR_TM4-6 PF06459.12 CDJ47738.1 - 2.2 8.0 9.0 2.2 8.1 9.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EIIBC-GUT_N PF03612.14 CDJ47738.1 - 3.1 7.5 9.2 3.3 7.4 9.2 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_S49_N PF08496.10 CDJ47738.1 - 3.3 7.8 11.8 3.5 7.7 11.8 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AIF_C PF14721.6 CDJ47738.1 - 3.4 8.0 7.8 3.8 7.9 7.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CSG2 PF16965.5 CDJ47738.1 - 3.5 6.5 3.8 3.6 6.4 3.8 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator ALMT PF11744.8 CDJ47738.1 - 5.2 5.8 6.5 5.3 5.8 6.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CLN3 PF02487.17 CDJ47738.1 - 5.3 6.0 7.5 5.3 6.0 7.5 1.0 1 0 0 1 1 1 0 CLN3 protein eIF-3_zeta PF05091.12 CDJ47738.1 - 5.4 5.9 18.0 5.2 5.9 18.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex14_N PF04695.13 CDJ47738.1 - 6 7.5 20.6 6.7 7.4 20.6 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.19 CDJ47738.1 - 6.2 4.6 11.5 6.7 4.5 11.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EOS1 PF12326.8 CDJ47738.1 - 6.4 6.7 7.1 6.6 6.6 7.1 1.0 1 0 0 1 1 1 0 N-glycosylation protein Connexin PF00029.19 CDJ47738.1 - 6.4 6.5 8.9 6.3 6.5 8.9 1.0 1 0 0 1 1 1 0 Connexin PAT1 PF09770.9 CDJ47738.1 - 6.5 4.9 21.0 7 4.8 21.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ47738.1 - 6.7 6.7 9.3 6.7 6.7 9.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ47738.1 - 6.8 6.6 32.7 7.1 6.5 32.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4770 PF15994.5 CDJ47738.1 - 6.9 6.9 15.8 7.7 6.7 15.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) CRF1 PF10380.9 CDJ47738.1 - 6.9 7.0 8.2 8.7 6.7 8.2 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 CCDC117 PF15810.5 CDJ47738.1 - 8.9 6.6 15.4 12 6.2 15.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 Gaa1 PF04114.14 CDJ47739.1 - 0.095 11.7 7.1 0.11 11.5 7.1 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component TMEM215 PF15746.5 CDJ47739.1 - 0.54 9.7 3.6 0.94 8.9 3.6 1.4 1 0 0 1 1 1 0 TMEM215 family DUF2722 PF10846.8 CDJ47739.1 - 0.62 8.9 30.5 0.014 14.4 18.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4603 PF15376.6 CDJ47740.1 - 0.006 14.1 0.2 0.0062 14.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4603) SPX PF03105.19 CDJ47740.1 - 0.14 12.0 4.0 0.18 11.7 4.0 1.1 1 0 0 1 1 1 0 SPX domain FTZ PF03867.14 CDJ47740.1 - 0.17 11.4 8.0 1.3 8.5 3.4 2.0 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region Ribosomal_60s PF00428.19 CDJ47740.1 - 0.85 10.2 11.7 1.3 9.6 11.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3138 PF11336.8 CDJ47740.1 - 3.6 6.1 10.6 5.2 5.6 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) AMA-1 PF02430.15 CDJ47742.1 - 1.7e-63 215.2 0.0 3e-61 207.8 0.0 2.0 1 1 0 1 1 1 1 Apical membrane antigen 1 TMEM51 PF15345.6 CDJ47742.1 - 0.0044 16.9 0.6 0.017 15.0 0.6 1.8 2 0 0 2 2 2 1 Transmembrane protein 51 EphA2_TM PF14575.6 CDJ47742.1 - 0.009 16.9 0.3 0.023 15.5 0.3 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 CDJ47742.1 - 0.074 14.0 1.1 0.17 12.9 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) LapA_dom PF06305.11 CDJ47742.1 - 0.12 12.2 2.0 0.82 9.5 1.2 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TFIIA PF03153.13 CDJ47742.1 - 0.4 10.6 11.0 0.65 9.9 6.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF533 PF04391.12 CDJ47742.1 - 0.55 9.8 8.5 0.13 11.9 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Spt20 PF12090.8 CDJ47742.1 - 9.5 5.8 17.1 18 4.9 17.1 1.4 1 0 0 1 1 1 0 Spt20 family TOM13 PF08219.11 CDJ47743.1 - 0.48 10.4 0.1 0.48 10.4 0.1 3.9 5 0 0 5 5 5 0 Outer membrane protein TOM13 DUF3169 PF11368.8 CDJ47743.1 - 7.3 6.0 6.4 0.25 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF2126 PF09899.9 CDJ47744.1 - 0.00033 18.9 7.5 0.00036 18.8 7.5 1.0 1 0 0 1 1 1 1 Putative amidoligase enzyme (DUF2126) DUF4199 PF13858.6 CDJ47744.1 - 0.00057 20.3 6.2 0.00066 20.1 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) DUF4834 PF16118.5 CDJ47744.1 - 0.00064 20.6 11.2 0.00089 20.2 11.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) OATP PF03137.20 CDJ47744.1 - 0.001 17.5 2.6 0.001 17.5 2.6 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Connexin PF00029.19 CDJ47744.1 - 0.0018 18.1 6.5 0.002 18.0 6.5 1.0 1 0 0 1 1 1 1 Connexin CLN3 PF02487.17 CDJ47744.1 - 0.0019 17.4 6.7 0.0019 17.3 6.7 1.0 1 0 0 1 1 1 1 CLN3 protein Zip PF02535.22 CDJ47744.1 - 0.0023 17.2 0.6 0.0026 17.0 0.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Folliculin PF11704.8 CDJ47744.1 - 0.0024 17.8 8.6 0.0025 17.7 8.6 1.0 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport V_ATPase_I PF01496.19 CDJ47744.1 - 0.0025 15.8 12.2 0.0026 15.8 12.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PRC2_HTH_1 PF18118.1 CDJ47744.1 - 0.0029 18.4 8.5 0.0034 18.1 8.5 1.1 1 0 0 1 1 1 1 Polycomb repressive complex 2 tri-helical domain FAM176 PF14851.6 CDJ47744.1 - 0.0034 17.0 3.8 0.0035 17.0 3.8 1.0 1 0 0 1 1 1 1 FAM176 family PIP5K PF01504.18 CDJ47744.1 - 0.0046 16.2 6.4 0.0046 16.2 6.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2347 PF09804.9 CDJ47744.1 - 0.0047 16.6 6.1 0.0052 16.4 6.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) FAM209 PF15206.6 CDJ47744.1 - 0.0058 16.4 1.1 0.0067 16.2 1.1 1.1 1 0 0 1 1 1 1 FAM209 family CDC45 PF02724.14 CDJ47744.1 - 0.0059 15.0 5.0 0.0059 15.0 5.0 1.0 1 0 0 1 1 1 1 CDC45-like protein EIIBC-GUT_N PF03612.14 CDJ47744.1 - 0.0073 16.1 10.9 0.0082 15.9 10.9 1.1 1 0 0 1 1 1 1 Sorbitol phosphotransferase enzyme II N-terminus Ctr PF04145.15 CDJ47744.1 - 0.0076 16.9 5.3 0.0083 16.8 5.3 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Folate_carrier PF01770.18 CDJ47744.1 - 0.009 14.8 6.1 0.01 14.6 6.1 1.0 1 0 0 1 1 1 1 Reduced folate carrier CPSF100_C PF13299.6 CDJ47744.1 - 0.0093 16.2 7.4 0.0095 16.1 7.4 1.1 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal SID-1_RNA_chan PF13965.6 CDJ47744.1 - 0.0097 14.4 3.6 0.01 14.3 3.6 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DUF913 PF06025.12 CDJ47744.1 - 0.014 14.4 3.5 0.014 14.4 3.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Cadherin_C_2 PF16492.5 CDJ47744.1 - 0.019 15.7 3.5 0.024 15.4 3.5 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal ATG22 PF11700.8 CDJ47744.1 - 0.02 13.6 1.7 0.021 13.5 1.7 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like FHIPEP PF00771.20 CDJ47744.1 - 0.021 13.3 7.9 0.024 13.1 7.9 1.0 1 0 0 1 1 1 0 FHIPEP family PEX11 PF05648.14 CDJ47744.1 - 0.022 14.2 5.6 0.025 14.0 5.6 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF719 PF05334.13 CDJ47744.1 - 0.022 15.0 7.8 0.024 14.9 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) DDHD PF02862.17 CDJ47744.1 - 0.026 14.7 9.4 0.027 14.7 9.4 1.0 1 0 0 1 1 1 0 DDHD domain G0-G1_switch_2 PF15103.6 CDJ47744.1 - 0.026 14.9 9.0 0.032 14.7 9.0 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 Eapp_C PF10238.9 CDJ47744.1 - 0.032 14.3 12.4 0.036 14.1 12.4 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein SpoIIP PF07454.11 CDJ47744.1 - 0.032 13.7 13.6 0.035 13.6 13.6 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CSG2 PF16965.5 CDJ47744.1 - 0.034 13.1 4.8 0.035 13.1 4.8 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator BRF1 PF07741.13 CDJ47744.1 - 0.039 14.3 8.5 0.046 14.1 8.5 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF2828 PF11443.8 CDJ47744.1 - 0.041 12.0 10.1 0.044 11.9 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RAB3GAP2_C PF14656.6 CDJ47744.1 - 0.043 12.1 11.1 0.047 11.9 11.1 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus FemAB PF02388.16 CDJ47744.1 - 0.043 12.7 12.7 0.049 12.5 12.7 1.0 1 0 0 1 1 1 0 FemAB family Pkinase_fungal PF17667.1 CDJ47744.1 - 0.043 12.6 6.6 0.048 12.4 6.6 1.0 1 0 0 1 1 1 0 Fungal protein kinase Scs3p PF10261.9 CDJ47744.1 - 0.044 13.3 4.0 0.047 13.2 4.0 1.0 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM AIF_C PF14721.6 CDJ47744.1 - 0.046 14.1 7.9 0.051 13.9 7.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Orf78 PF06024.12 CDJ47744.1 - 0.051 13.9 5.7 0.067 13.5 5.7 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Kei1 PF08552.11 CDJ47744.1 - 0.052 13.4 5.8 0.058 13.3 5.8 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF5308 PF17233.2 CDJ47744.1 - 0.056 13.7 8.5 0.06 13.6 8.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF3402 PF11882.8 CDJ47744.1 - 0.062 12.4 12.3 0.068 12.3 12.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Tim54 PF11711.8 CDJ47744.1 - 0.066 12.0 9.8 0.072 11.9 9.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Otopetrin PF03189.13 CDJ47744.1 - 0.068 12.0 5.4 0.072 11.9 5.4 1.0 1 0 0 1 1 1 0 Otopetrin RPA43_OB PF17875.1 CDJ47744.1 - 0.071 13.7 6.1 0.077 13.6 6.1 1.1 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RMP PF14996.6 CDJ47744.1 - 0.076 13.2 11.4 0.09 13.0 11.4 1.0 1 0 0 1 1 1 0 Retinal Maintenance DUF3276 PF11680.8 CDJ47744.1 - 0.082 13.0 8.2 0.097 12.8 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Serinc PF03348.15 CDJ47744.1 - 0.084 11.8 5.7 0.087 11.7 5.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) SLC12 PF03522.15 CDJ47744.1 - 0.084 11.9 11.6 0.088 11.8 11.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FTO_NTD PF12933.7 CDJ47744.1 - 0.085 12.1 7.4 0.096 11.9 7.4 1.0 1 0 0 1 1 1 0 FTO catalytic domain D123 PF07065.14 CDJ47744.1 - 0.091 11.9 10.2 0.11 11.6 10.2 1.0 1 0 0 1 1 1 0 D123 MecA PF05389.12 CDJ47744.1 - 0.094 12.3 10.1 0.1 12.2 10.1 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) EOS1 PF12326.8 CDJ47744.1 - 0.11 12.4 6.7 0.13 12.2 6.7 1.1 1 0 0 1 1 1 0 N-glycosylation protein Gti1_Pac2 PF09729.9 CDJ47744.1 - 0.11 12.5 8.9 0.13 12.4 8.9 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family Peroxin-13_N PF04088.13 CDJ47744.1 - 0.12 12.7 7.2 0.13 12.5 7.2 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Neur_chan_memb PF02932.16 CDJ47744.1 - 0.12 12.4 9.5 0.14 12.2 9.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CBP_BcsG PF11658.8 CDJ47744.1 - 0.12 10.7 10.8 0.14 10.6 10.8 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Pinin_SDK_memA PF04696.13 CDJ47744.1 - 0.13 12.4 27.1 0.14 12.2 27.1 1.0 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Sec62 PF03839.16 CDJ47744.1 - 0.13 11.8 7.2 0.14 11.6 7.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Rxt3 PF08642.10 CDJ47744.1 - 0.13 13.0 5.6 0.16 12.8 5.6 1.1 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF3464 PF11947.8 CDJ47744.1 - 0.15 11.8 13.7 0.18 11.6 13.7 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF1764 PF08576.10 CDJ47744.1 - 0.16 12.9 10.5 0.19 12.6 10.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) MTBP_C PF14920.6 CDJ47744.1 - 0.16 11.7 11.1 0.19 11.4 11.1 1.1 1 0 0 1 1 1 0 MDM2-binding TFB6 PF17110.5 CDJ47744.1 - 0.18 11.6 8.1 0.2 11.4 8.1 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF3381 PF11861.8 CDJ47744.1 - 0.18 11.6 14.8 0.21 11.4 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF2140 PF09911.9 CDJ47744.1 - 0.19 11.3 8.1 0.27 10.8 8.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Presenilin PF01080.17 CDJ47744.1 - 0.19 10.5 16.0 0.21 10.3 16.0 1.1 1 0 0 1 1 1 0 Presenilin HemX PF04375.14 CDJ47744.1 - 0.21 10.8 28.3 0.21 10.8 28.3 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CobT PF06213.12 CDJ47744.1 - 0.22 10.9 21.7 0.26 10.7 21.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT UPF0239 PF06783.11 CDJ47744.1 - 0.22 11.7 6.1 0.28 11.4 6.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) ORC_WH_C PF18137.1 CDJ47744.1 - 0.23 11.5 13.1 0.26 11.3 13.1 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF1980 PF09323.10 CDJ47744.1 - 0.25 11.2 9.6 0.26 11.2 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) NicO PF03824.16 CDJ47744.1 - 0.26 10.6 2.3 0.29 10.4 2.3 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein LIM_bind PF01803.16 CDJ47744.1 - 0.27 10.7 12.6 0.28 10.7 12.6 1.0 1 0 0 1 1 1 0 LIM-domain binding protein Baculo_PP31 PF05311.11 CDJ47744.1 - 0.29 10.6 12.9 0.33 10.4 12.9 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FAM91_C PF14648.6 CDJ47744.1 - 0.3 9.9 7.6 0.33 9.8 7.6 1.1 1 0 0 1 1 1 0 FAM91 C-terminus eIF-3_zeta PF05091.12 CDJ47744.1 - 0.3 10.0 20.4 0.33 9.9 20.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HNOBA PF07701.14 CDJ47744.1 - 0.33 10.3 12.1 0.38 10.1 12.1 1.1 1 0 0 1 1 1 0 Heme NO binding associated Band_3_cyto PF07565.13 CDJ47744.1 - 0.34 10.7 13.2 0.38 10.5 13.2 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_M18 PF02127.15 CDJ47744.1 - 0.34 9.6 6.2 0.42 9.4 6.2 1.0 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) DUF5327 PF17261.2 CDJ47744.1 - 0.38 11.5 23.4 0.53 11.1 23.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Velvet PF11754.8 CDJ47744.1 - 0.39 10.6 12.9 0.43 10.5 12.9 1.0 1 0 0 1 1 1 0 Velvet factor MMU163 PF17119.5 CDJ47744.1 - 0.41 9.8 5.5 0.44 9.6 5.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis O-antigen_lig PF13425.6 CDJ47744.1 - 0.41 9.4 3.9 0.41 9.4 3.9 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Nucleoside_tran PF01733.18 CDJ47744.1 - 0.42 10.0 6.2 0.46 9.8 6.2 1.0 1 0 0 1 1 1 0 Nucleoside transporter MDM31_MDM32 PF08118.11 CDJ47744.1 - 0.44 9.2 10.3 0.5 9.0 10.3 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Ureide_permease PF07168.11 CDJ47744.1 - 0.45 9.2 4.8 0.47 9.1 4.8 1.0 1 0 0 1 1 1 0 Ureide permease HCO3_cotransp PF00955.21 CDJ47744.1 - 0.46 9.3 3.8 0.46 9.2 3.8 1.0 1 0 0 1 1 1 0 HCO3- transporter family CemA PF03040.14 CDJ47744.1 - 0.46 10.4 7.6 0.56 10.1 7.6 1.0 1 0 0 1 1 1 0 CemA family DNA_pol3_a_NII PF11490.8 CDJ47744.1 - 0.49 10.3 21.7 0.65 9.9 21.7 1.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II DIE2_ALG10 PF04922.12 CDJ47744.1 - 0.49 9.6 3.9 0.65 9.2 3.9 1.2 1 0 0 1 1 1 0 DIE2/ALG10 family ABC2_membrane_2 PF12679.7 CDJ47744.1 - 0.51 9.6 6.4 0.51 9.6 6.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4746 PF15928.5 CDJ47744.1 - 0.53 9.7 10.3 0.58 9.5 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CCDC53 PF10152.9 CDJ47744.1 - 0.55 10.6 15.3 0.64 10.4 15.3 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CD20 PF04103.15 CDJ47744.1 - 0.58 10.2 1.8 0.66 10.1 1.8 1.3 1 0 0 1 1 1 0 CD20-like family PPL5 PF18168.1 CDJ47744.1 - 0.6 9.4 8.6 0.67 9.2 8.6 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Gastrin PF00918.17 CDJ47744.1 - 0.62 11.0 10.8 0.67 10.9 10.8 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family MPM1 PF17234.2 CDJ47744.1 - 0.72 10.1 16.1 0.95 9.7 16.1 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 MDM10 PF12519.8 CDJ47744.1 - 0.73 8.6 11.0 0.8 8.5 11.0 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 YABBY PF04690.13 CDJ47744.1 - 0.73 10.4 11.4 0.82 10.2 11.4 1.1 1 0 0 1 1 1 0 YABBY protein FAM60A PF15396.6 CDJ47744.1 - 0.76 9.7 10.2 0.86 9.6 10.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A FPN1 PF06963.12 CDJ47744.1 - 0.81 8.2 6.5 0.88 8.1 6.5 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) NARP1 PF12569.8 CDJ47744.1 - 0.81 8.5 13.4 0.89 8.4 13.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4770 PF15994.5 CDJ47744.1 - 0.83 9.9 18.6 1 9.5 18.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) ALMT PF11744.8 CDJ47744.1 - 0.84 8.4 10.3 0.9 8.3 10.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter FliP PF00813.20 CDJ47744.1 - 0.87 9.4 6.4 1 9.2 6.4 1.1 1 0 0 1 1 1 0 FliP family GNAT_acetyltr_2 PF13718.6 CDJ47744.1 - 0.9 8.9 10.5 1.1 8.7 10.5 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 LpxB PF02684.15 CDJ47744.1 - 0.91 8.3 13.5 0.98 8.2 13.5 1.0 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase PAT1 PF09770.9 CDJ47744.1 - 0.98 7.6 27.4 1.1 7.5 27.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3675 PF12428.8 CDJ47744.1 - 1.1 9.9 4.6 1.3 9.6 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF4638 PF15472.6 CDJ47744.1 - 1.1 8.9 11.9 1.2 8.8 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) RR_TM4-6 PF06459.12 CDJ47744.1 - 1.2 8.9 15.1 1.4 8.7 15.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4446 PF14584.6 CDJ47744.1 - 1.2 9.1 6.3 1.5 8.8 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF1644 PF07800.12 CDJ47744.1 - 1.4 8.9 11.3 1.7 8.7 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Glt_symporter PF03616.14 CDJ47744.1 - 1.5 7.4 6.4 1.7 7.2 6.4 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter DcuA_DcuB PF03605.14 CDJ47744.1 - 1.5 7.6 4.5 1.6 7.5 4.5 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter RNA_pol_Rbc25 PF08292.12 CDJ47744.1 - 1.5 9.0 14.3 2.9 8.1 14.3 1.5 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 MCU PF04678.13 CDJ47744.1 - 1.5 8.8 10.5 1.7 8.7 10.5 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter PigN PF04987.14 CDJ47744.1 - 1.6 7.5 8.6 2 7.2 8.6 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Tmem26 PF09772.9 CDJ47744.1 - 1.7 8.0 8.8 2 7.7 8.8 1.0 1 0 0 1 1 1 0 Transmembrane protein 26 MENTAL PF10457.9 CDJ47744.1 - 1.7 8.4 5.7 2.1 8.1 5.7 1.2 1 0 0 1 1 1 0 Cholesterol-capturing domain Peptidase_S49_N PF08496.10 CDJ47744.1 - 1.8 8.6 13.5 2.2 8.4 13.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RED_N PF07808.13 CDJ47744.1 - 1.8 8.1 18.7 2.1 7.9 18.7 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region PepSY_TM PF03929.16 CDJ47744.1 - 1.8 8.2 9.9 1.9 8.0 9.9 1.1 1 0 0 1 1 1 0 PepSY-associated TM region ATAD4 PF15321.6 CDJ47744.1 - 1.8 9.9 9.8 2.5 9.5 9.8 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF4407 PF14362.6 CDJ47744.1 - 1.9 7.7 20.5 2.2 7.5 20.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CRF1 PF10380.9 CDJ47744.1 - 2 8.8 7.2 2.8 8.3 7.2 1.2 1 0 0 1 1 1 0 Transcription factor CRF1 HGTP_anticodon2 PF12745.7 CDJ47744.1 - 2.1 7.8 15.2 2.5 7.6 15.2 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs MTP18 PF10558.9 CDJ47744.1 - 2.3 8.1 6.3 2.6 8.0 6.3 1.1 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) MAT1 PF06391.13 CDJ47744.1 - 2.4 7.9 23.9 2.9 7.7 23.9 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 CTU2 PF10288.9 CDJ47744.1 - 2.5 8.4 16.7 3.5 7.9 16.7 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 MscS_TM PF12794.7 CDJ47744.1 - 2.5 6.9 11.3 3.2 6.5 11.3 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF853 PF05872.12 CDJ47744.1 - 2.6 6.5 13.0 2.9 6.4 13.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF2946 PF11162.8 CDJ47744.1 - 2.6 8.7 7.2 3.3 8.4 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF3405 PF11885.8 CDJ47744.1 - 2.7 6.5 13.1 3 6.4 13.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Het-C PF07217.11 CDJ47744.1 - 2.7 6.4 11.9 3 6.3 11.9 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Cellulose_synt PF03552.14 CDJ47744.1 - 2.8 6.3 5.2 3 6.2 5.2 1.0 1 0 0 1 1 1 0 Cellulose synthase Suf PF05843.14 CDJ47744.1 - 2.9 7.8 22.5 3.7 7.5 22.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF5385 PF17359.2 CDJ47744.1 - 2.9 7.4 18.0 3.5 7.1 18.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Membralin PF09746.9 CDJ47744.1 - 3 6.8 9.8 3.4 6.6 9.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein Paf1 PF03985.13 CDJ47744.1 - 3 6.7 18.4 3.6 6.5 18.4 1.0 1 0 0 1 1 1 0 Paf1 Pex14_N PF04695.13 CDJ47744.1 - 3.2 8.4 28.3 3.7 8.2 28.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 CDJ47744.1 - 3.5 7.6 25.7 4.1 7.4 25.7 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ArAE_2_N PF10337.9 CDJ47744.1 - 3.5 6.6 11.3 4.3 6.3 11.3 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal EMC3_TMCO1 PF01956.16 CDJ47744.1 - 3.7 7.3 15.1 4.2 7.1 15.1 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like TMEM51 PF15345.6 CDJ47744.1 - 3.9 7.3 18.2 4.9 6.9 18.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Ndc1_Nup PF09531.10 CDJ47744.1 - 4.2 6.0 12.8 4.5 5.8 12.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM150 PF15129.6 CDJ47744.1 - 4.2 7.5 17.7 5.1 7.3 17.7 1.1 1 0 0 1 1 1 0 FAM150 family Peptidase_S15 PF02129.18 CDJ47744.1 - 4.4 6.8 12.1 4.9 6.7 12.1 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) NEMP PF10225.9 CDJ47744.1 - 4.7 6.8 7.0 5.4 6.6 7.0 1.0 1 0 0 1 1 1 0 NEMP family PP_kinase_N PF13089.6 CDJ47744.1 - 4.9 7.5 15.7 6.5 7.1 15.7 1.2 1 0 0 1 1 1 0 Polyphosphate kinase N-terminal domain Asparaginase_2 PF01112.18 CDJ47744.1 - 5 6.1 9.2 5.4 6.0 9.2 1.0 1 0 0 1 1 1 0 Asparaginase Mem_trans PF03547.18 CDJ47744.1 - 5 5.4 6.2 5.1 5.4 6.2 1.0 1 0 0 1 1 1 0 Membrane transport protein CAF1 PF04857.20 CDJ47744.1 - 5 6.2 11.6 6.3 5.9 11.6 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease EPL1 PF10513.9 CDJ47744.1 - 5.1 7.5 19.0 6.2 7.2 19.0 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like AAA_28 PF13521.6 CDJ47744.1 - 5.5 7.2 7.3 6.4 7.0 7.3 1.1 1 0 0 1 1 1 0 AAA domain Ufd2P_core PF10408.9 CDJ47744.1 - 5.9 5.4 17.6 6.4 5.2 17.6 1.0 1 0 0 1 1 1 0 Ubiquitin elongating factor core Pal1 PF08316.11 CDJ47744.1 - 6.5 7.5 8.1 7.3 7.4 8.1 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Hid1 PF12722.7 CDJ47744.1 - 6.5 4.8 15.1 7 4.6 15.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pex26 PF07163.12 CDJ47744.1 - 7.3 5.8 16.8 9 5.5 16.8 1.2 1 0 0 1 1 1 0 Pex26 protein Endonuc_Holl PF10107.9 CDJ47744.1 - 7.4 6.4 13.7 8.7 6.2 13.7 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase RBM39linker PF15519.6 CDJ47744.1 - 8.5 7.5 16.3 12 7.1 16.3 1.2 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein AAA_23 PF13476.6 CDJ47744.1 - 8.7 6.8 21.3 10 6.5 21.3 1.3 1 0 0 1 1 1 0 AAA domain Coilin_N PF15862.5 CDJ47744.1 - 8.9 6.1 19.7 14 5.5 19.7 1.3 1 0 0 1 1 1 0 Coilin N-terminus TFIIA PF03153.13 CDJ47744.1 - 9 6.2 45.3 10 6.0 45.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF543 PF04418.12 CDJ47744.1 - 9.2 6.3 9.0 86 3.2 9.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF543) vATP-synt_AC39 PF01992.16 CDJ47745.1 - 5.9e-52 177.2 1.2 2.4e-29 102.9 0.0 2.0 2 0 0 2 2 2 2 ATP synthase (C/AC39) subunit SUIM_assoc PF16619.5 CDJ47745.1 - 0.00058 19.9 27.2 0.39 10.8 8.3 3.4 3 0 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 DUF5085 PF16895.5 CDJ47745.1 - 0.17 12.2 1.3 0.48 10.8 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5085) Phostensin_N PF13916.6 CDJ47745.1 - 2.5 8.5 12.3 2.6 8.4 1.8 3.3 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal ANAPC_CDC26 PF10471.9 CDJ47745.1 - 7.3 7.5 23.3 15 6.5 1.8 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 DUF2749 PF10907.8 CDJ47746.1 - 0.017 15.3 0.9 0.017 15.3 0.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) HemY_N PF07219.13 CDJ47746.1 - 0.091 13.0 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 HemY protein N-terminus DUF5305 PF17231.2 CDJ47746.1 - 0.52 9.7 16.1 0.63 9.4 16.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4220 PF13968.6 CDJ47746.1 - 0.89 8.9 9.5 1 8.7 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Stevor PF17410.2 CDJ47746.1 - 2.3 7.7 17.2 2.6 7.5 17.2 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Peptidase_M56 PF05569.11 CDJ47746.1 - 3.4 6.8 9.1 4.1 6.5 9.1 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 EphA2_TM PF14575.6 CDJ47746.1 - 5.4 8.0 8.5 0.57 11.1 2.0 2.2 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MCU PF04678.13 CDJ47747.1 - 3.5 7.7 15.2 3.7 7.6 15.2 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Utp11 PF03998.13 CDJ47748.1 - 0.00032 20.7 16.0 0.00032 20.7 16.0 2.3 2 0 0 2 2 2 1 Utp11 protein Pex14_N PF04695.13 CDJ47748.1 - 0.00048 20.8 7.8 0.00048 20.8 7.8 7.6 1 1 4 7 7 7 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.9 CDJ47748.1 - 0.02 15.2 0.6 0.02 15.2 0.6 8.7 1 1 2 6 6 6 0 Anti-sigma-K factor rskA Cation_ATPase_C PF00689.21 CDJ47749.1 - 5.9e-52 176.0 0.7 1.3e-51 174.9 0.7 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CDJ47749.1 - 3.2e-50 170.1 4.5 3.7e-50 170.0 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CDJ47749.1 - 1.3e-21 76.1 0.1 5.4e-21 74.1 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CDJ47749.1 - 1.5e-20 74.4 7.9 1e-19 71.7 7.9 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ47749.1 - 4e-19 68.5 0.1 7.7e-19 67.6 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDJ47749.1 - 2.5e-06 27.4 0.5 2.3e-05 24.3 0.5 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ47749.1 - 0.00089 19.7 0.0 0.0054 17.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Chorion_2 PF03964.15 CDJ47749.1 - 0.19 12.6 5.3 0.5 11.2 5.3 1.6 1 0 0 1 1 1 0 Chorion family 2 DUF3810 PF12725.7 CDJ47749.1 - 0.2 11.0 0.5 0.55 9.5 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Ribosomal_60s PF00428.19 CDJ47749.1 - 4.8 7.8 9.1 15 6.2 9.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sporozoite_P67 PF05642.11 CDJ47751.1 - 0.0019 16.4 0.9 0.0019 16.4 0.9 2.7 2 1 1 3 3 3 1 Sporozoite P67 surface antigen SR-25 PF10500.9 CDJ47751.1 - 0.0095 15.6 8.0 0.0095 15.6 8.0 5.4 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ47751.1 - 0.035 14.2 47.9 0.2 11.7 4.6 5.1 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Tau95_N PF17682.1 CDJ47751.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.9 4 0 0 4 4 4 0 Tau95 Triple barrel domain DUF1712 PF08217.11 CDJ47751.1 - 0.59 8.5 10.0 0.064 11.7 3.9 2.2 3 0 0 3 3 3 0 Fungal domain of unknown function (DUF1712) DUF4667 PF15700.5 CDJ47751.1 - 3.9 7.5 34.1 0.31 11.1 13.8 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4667) TMEM65 PF10507.9 CDJ47751.1 - 4 7.4 4.4 6.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Transmembrane protein 65 Miga PF10265.9 CDJ47751.1 - 4.5 6.1 20.8 0.04 12.9 10.3 2.5 3 0 0 3 3 3 0 Mitoguardin MMU163 PF17119.5 CDJ47751.1 - 6.2 5.9 5.8 31 3.6 5.8 2.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis PIP5K PF01504.18 CDJ47751.1 - 7.6 5.7 8.5 1.6 7.9 0.6 3.1 3 1 0 3 3 3 0 Phosphatidylinositol-4-phosphate 5-Kinase Methyltrans_RNA PF04452.14 CDJ47752.1 - 3.8e-12 46.0 0.1 3.8e-12 46.0 0.1 2.8 2 1 0 2 2 2 1 RNA methyltransferase RskA PF10099.9 CDJ47752.1 - 0.0069 16.7 0.9 0.0069 16.7 0.9 4.1 1 1 3 4 4 4 3 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ47753.1 - 0.012 15.2 13.4 0.012 15.2 13.4 4.9 3 1 1 4 4 4 0 Nuclear RNA-splicing-associated protein RIFIN PF02009.16 CDJ47754.1 - 0.034 14.0 14.0 0.047 13.6 14.0 1.2 1 0 0 1 1 1 0 Rifin EIF4E-T PF10477.9 CDJ47754.1 - 0.04 12.7 14.9 0.043 12.6 14.9 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E G6B PF15096.6 CDJ47754.1 - 0.047 13.5 2.4 0.064 13.0 2.4 1.3 1 0 0 1 1 1 0 G6B family TFIIA PF03153.13 CDJ47754.1 - 0.049 13.6 35.6 0.066 13.2 35.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ47754.1 - 0.13 11.0 44.4 0.15 10.7 44.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MCU PF04678.13 CDJ47754.1 - 0.17 11.9 10.1 0.22 11.6 10.1 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter BAF1_ABF1 PF04684.13 CDJ47754.1 - 0.26 10.3 11.5 0.28 10.2 11.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GREB1 PF15782.5 CDJ47754.1 - 0.34 8.0 12.3 0.35 8.0 12.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AUX_IAA PF02309.16 CDJ47754.1 - 0.4 10.5 5.2 0.4 10.5 5.2 1.2 1 0 0 1 1 1 0 AUX/IAA family PAT1 PF09770.9 CDJ47754.1 - 0.45 8.7 25.1 0.48 8.6 25.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Draxin PF15550.6 CDJ47754.1 - 0.46 10.3 8.9 0.55 10.0 8.9 1.0 1 0 0 1 1 1 0 Draxin Membralin PF09746.9 CDJ47754.1 - 0.65 9.0 3.3 0.77 8.7 3.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Neur_chan_memb PF02932.16 CDJ47754.1 - 0.67 10.0 6.3 0.75 9.8 6.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ47754.1 - 0.73 9.6 9.0 0.79 9.5 9.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cyt_bd_oxida_II PF02322.15 CDJ47754.1 - 0.75 9.1 11.9 2.2 7.6 0.1 2.0 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II SpoIIP PF07454.11 CDJ47754.1 - 1 8.7 8.3 1.2 8.5 8.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 CDJ47754.1 - 1.1 9.4 8.6 1.4 9.1 8.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF853 PF05872.12 CDJ47754.1 - 1.2 7.6 15.5 1.4 7.5 15.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) MCD PF05292.11 CDJ47754.1 - 1.2 8.6 7.6 1.6 8.2 7.6 1.2 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain V_ATPase_I PF01496.19 CDJ47754.1 - 1.4 6.8 7.8 1.5 6.6 7.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3573 PF12097.8 CDJ47754.1 - 1.5 7.6 7.5 1.7 7.4 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Med26_C PF15693.5 CDJ47754.1 - 1.8 8.7 13.2 2.4 8.3 13.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal EPL1 PF10513.9 CDJ47754.1 - 2.7 8.4 9.6 4.1 7.8 9.6 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Lin-8 PF03353.15 CDJ47754.1 - 3 7.3 14.5 3.6 7.0 14.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CCSAP PF15748.5 CDJ47754.1 - 3.1 7.9 12.8 4.4 7.4 12.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CemA PF03040.14 CDJ47754.1 - 3.2 7.6 5.8 4 7.3 5.8 1.1 1 0 0 1 1 1 0 CemA family AAA_23 PF13476.6 CDJ47754.1 - 3.3 8.2 16.6 4 7.9 16.6 1.1 1 0 0 1 1 1 0 AAA domain Mcm10 PF09332.11 CDJ47754.1 - 5.1 6.4 15.3 6.6 6.0 15.3 1.1 1 0 0 1 1 1 0 Mcm10 replication factor TERB2 PF15101.6 CDJ47754.1 - 6.8 6.7 17.8 9.8 6.2 17.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ47756.1 - 0.0031 17.2 22.4 0.0031 17.2 22.4 2.2 2 0 0 2 2 2 1 Spt20 family DUF2722 PF10846.8 CDJ47756.1 - 0.008 15.2 12.7 0.008 15.2 12.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF4401 PF14351.6 CDJ47756.1 - 0.18 11.1 5.8 0.23 10.7 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) SAP130_C PF16014.5 CDJ47756.1 - 0.47 9.5 24.3 0.57 9.2 24.3 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus FAM176 PF14851.6 CDJ47756.1 - 0.96 9.1 20.0 1.8 8.2 3.7 2.2 2 0 0 2 2 2 0 FAM176 family SpoIIP PF07454.11 CDJ47756.1 - 1 8.8 25.0 1.2 8.5 6.2 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Paf1 PF03985.13 CDJ47756.1 - 1.4 7.9 29.8 2.2 7.2 8.8 2.0 2 0 0 2 2 2 0 Paf1 PTPRCAP PF15713.5 CDJ47756.1 - 1.6 9.0 30.9 3.7 7.8 11.1 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated VIR_N PF15912.5 CDJ47756.1 - 1.6 8.3 17.2 0.27 10.8 5.7 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal MAM33 PF02330.16 CDJ47756.1 - 2.2 8.2 24.0 0.19 11.7 2.1 2.1 2 0 0 2 2 2 0 Mitochondrial glycoprotein Coilin_N PF15862.5 CDJ47756.1 - 2.7 7.8 27.3 3.4 7.5 6.8 2.3 2 0 0 2 2 2 0 Coilin N-terminus eIF_4EBP PF05456.11 CDJ47756.1 - 3.1 7.8 21.8 4.8 7.1 8.8 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Peptidase_U57 PF05582.12 CDJ47756.1 - 3.6 6.7 20.0 0.16 11.2 6.5 2.1 2 0 0 2 2 2 0 YabG peptidase U57 Afi1 PF07792.12 CDJ47756.1 - 4.4 7.8 18.6 7.1 7.1 3.8 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4770 PF15994.5 CDJ47756.1 - 8 6.7 25.9 2.3 8.4 5.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) NST1 PF13945.6 CDJ47756.1 - 8.2 6.5 32.2 0.41 10.7 13.2 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF3381 PF11861.8 CDJ47756.1 - 8.5 6.1 28.4 2.8 7.7 7.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) TFB6 PF17110.5 CDJ47756.1 - 8.7 6.1 17.8 6.3 6.5 3.5 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Connexin PF00029.19 CDJ47756.1 - 8.8 6.0 19.6 5 6.8 4.7 2.1 2 0 0 2 2 2 0 Connexin DDRGK PF09756.9 CDJ47756.1 - 8.9 5.9 34.9 7.5 6.1 12.8 2.1 2 0 0 2 2 2 0 DDRGK domain DUF5349 PF17298.2 CDJ47757.1 - 0.62 9.8 5.3 7.4 6.2 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5349) DUF2722 PF10846.8 CDJ47757.1 - 4.3 6.2 20.0 1.3 7.9 6.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Asp-B-Hydro_N PF05279.11 CDJ47758.1 - 5.9 6.9 37.4 7.8 6.5 37.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC27 PF09507.10 CDJ47758.1 - 9.2 5.5 52.5 12 5.2 52.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop53 PF07767.11 CDJ47759.1 - 0.015 14.7 13.3 0.019 14.4 13.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SAGA-Tad1 PF12767.7 CDJ47759.1 - 0.63 9.7 15.6 0.84 9.3 15.6 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Nha1_C PF08619.10 CDJ47759.1 - 1.1 8.4 17.1 1.6 7.8 17.1 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus PAT1 PF09770.9 CDJ47759.1 - 2.4 6.3 40.0 2.7 6.1 40.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 CDJ47760.1 - 0.0023 17.6 14.4 0.0073 15.9 14.4 1.9 1 0 0 1 1 1 1 Spt20 family DUF4746 PF15928.5 CDJ47760.1 - 0.018 14.5 3.6 1.4 8.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RAB3GAP2_C PF14656.6 CDJ47760.1 - 0.025 12.8 2.0 0.051 11.8 2.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF2052 PF09747.9 CDJ47760.1 - 2.1 8.4 17.8 0.45 10.6 3.4 2.8 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 CDJ47760.1 - 3.6 5.8 13.5 3.7 5.7 4.0 2.3 2 0 0 2 2 2 0 CDC45-like protein SpoIIP PF07454.11 CDJ47760.1 - 4 6.8 10.1 0.32 10.4 2.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Afi1 PF07792.12 CDJ47760.1 - 4.1 7.9 10.4 0.58 10.6 1.9 2.7 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SUIM_assoc PF16619.5 CDJ47761.1 - 0.00016 21.7 5.0 0.0024 17.9 1.5 14.5 11 4 0 11 11 11 5 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ47761.1 - 0.00064 20.1 5.4 0.00064 20.1 5.4 9.2 2 2 3 5 5 5 2 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 CDJ47761.1 - 0.0022 17.1 0.0 0.0022 17.1 0.0 5.7 2 1 1 4 4 4 1 BAF1 / ABF1 chromatin reorganising factor Mem_trans PF03547.18 CDJ47761.1 - 0.023 13.1 0.0 1 7.7 0.0 3.3 2 1 1 3 3 3 0 Membrane transport protein Activator_LAG-3 PF11498.8 CDJ47762.1 - 0.0012 17.9 24.2 0.0018 17.3 24.2 1.3 1 0 0 1 1 1 1 Transcriptional activator LAG-3 RskA PF10099.9 CDJ47762.1 - 0.0013 19.1 25.5 0.46 10.8 25.5 2.7 1 1 0 1 1 1 1 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ47762.1 - 0.028 14.9 0.6 30 5.2 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) Presenilin PF01080.17 CDJ47762.1 - 0.062 12.1 3.8 0.059 12.1 3.8 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ47762.1 - 4 5.6 18.2 6.5 4.9 18.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ47764.1 - 5e-05 23.0 25.7 7e-05 22.5 25.7 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MAP7 PF05672.11 CDJ47764.1 - 0.038 13.7 36.9 0.043 13.5 36.9 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family CCSAP PF15748.5 CDJ47764.1 - 0.049 13.8 30.8 0.057 13.6 30.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TCP PF03634.13 CDJ47764.1 - 0.39 11.3 31.5 0.48 11.0 31.5 1.1 1 0 0 1 1 1 0 TCP family transcription factor STAC2_u1 PF16664.5 CDJ47764.1 - 1.1 9.7 22.5 1.6 9.2 22.5 1.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 SMYLE_N PF18615.1 CDJ47764.1 - 1.1 8.8 21.5 1.3 8.5 21.5 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain AAA_23 PF13476.6 CDJ47764.1 - 1.2 9.6 33.1 1.3 9.5 33.1 1.0 1 0 0 1 1 1 0 AAA domain DUF2052 PF09747.9 CDJ47764.1 - 2 8.5 24.6 2.3 8.3 24.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4746 PF15928.5 CDJ47764.1 - 3.2 7.1 15.6 3.8 6.8 15.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Dsh_C PF12316.8 CDJ47764.1 - 3.3 8.0 26.2 3.9 7.8 26.2 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Peptidase_S64 PF08192.11 CDJ47764.1 - 4.3 5.7 26.8 5.1 5.5 26.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Asp-B-Hydro_N PF05279.11 CDJ47764.1 - 5.7 6.9 16.3 6.1 6.8 16.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4407 PF14362.6 CDJ47764.1 - 6.9 5.9 22.5 9.3 5.5 22.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hamartin PF04388.12 CDJ47764.1 - 7.4 5.1 32.9 7.7 5.0 32.9 1.0 1 0 0 1 1 1 0 Hamartin protein Peptidase_S49_N PF08496.10 CDJ47764.1 - 7.8 6.5 21.4 10 6.1 21.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peptidase_S15 PF02129.18 CDJ47764.1 - 8 6.0 15.4 8.8 5.8 15.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) RR_TM4-6 PF06459.12 CDJ47764.1 - 9.6 5.9 28.2 11 5.8 28.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SKIP_SNW PF02731.15 CDJ47765.1 - 1.4e-69 232.8 2.4 1.4e-69 232.8 2.4 3.0 4 0 0 4 4 4 1 SKIP/SNW domain Pro_isomerase PF00160.21 CDJ47766.1 - 5.3e-17 62.5 0.0 6.5e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 CDJ47766.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain RskA PF10099.9 CDJ47767.1 - 0.098 12.9 11.2 0.1 12.9 11.2 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2057 PF09829.9 CDJ47767.1 - 1.8 8.7 3.8 2 8.6 3.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Spt20 PF12090.8 CDJ47768.1 - 0.00051 19.7 12.2 0.00067 19.3 12.2 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ47768.1 - 0.0012 18.9 17.1 0.0015 18.7 17.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ47768.1 - 0.0088 15.0 9.5 0.012 14.6 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RPA43_OB PF17875.1 CDJ47768.1 - 0.044 14.4 1.5 0.044 14.4 1.5 1.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I FHIPEP PF00771.20 CDJ47768.1 - 0.055 11.9 3.2 0.063 11.7 3.2 1.1 1 0 0 1 1 1 0 FHIPEP family Roughex PF06020.11 CDJ47768.1 - 0.2 10.7 4.0 0.26 10.4 4.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein RIFIN PF02009.16 CDJ47768.1 - 0.21 11.5 9.2 0.29 11.0 9.2 1.2 1 0 0 1 1 1 0 Rifin DcuC PF03606.15 CDJ47768.1 - 0.21 10.0 2.6 0.38 9.2 2.6 1.3 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF2681 PF10883.8 CDJ47768.1 - 0.28 11.6 11.2 0.78 10.2 11.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Presenilin PF01080.17 CDJ47768.1 - 0.43 9.3 5.1 0.54 9.0 5.1 1.1 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 CDJ47768.1 - 0.53 10.3 9.9 0.9 9.5 9.9 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Myc_N PF01056.18 CDJ47768.1 - 0.55 10.1 8.9 0.83 9.5 8.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RskA PF10099.9 CDJ47768.1 - 0.56 10.5 47.4 1.2 9.4 25.4 2.5 2 1 0 2 2 2 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ47769.1 - 4.3e-05 23.5 0.0 4.3e-05 23.5 0.0 10.7 3 2 3 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 LAP1C PF05609.12 CDJ47770.1 - 1.7 7.6 35.9 2.8 6.9 35.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hamartin PF04388.12 CDJ47770.1 - 3.5 6.2 36.6 4.2 5.9 36.6 1.0 1 0 0 1 1 1 0 Hamartin protein Vac7 PF12751.7 CDJ47770.1 - 7 6.0 15.9 11 5.3 15.9 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Draxin PF15550.6 CDJ47770.1 - 7.3 6.4 25.0 9.9 5.9 25.0 1.2 1 0 0 1 1 1 0 Draxin DUF4179 PF13786.6 CDJ47771.1 - 0.041 14.4 3.1 0.059 13.8 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF2722 PF10846.8 CDJ47771.1 - 0.077 11.9 13.6 0.074 12.0 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2232 PF09991.9 CDJ47771.1 - 0.17 11.1 1.9 0.2 10.8 1.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) RXLR PF16810.5 CDJ47771.1 - 0.18 12.3 4.9 0.23 11.9 4.9 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Roughex PF06020.11 CDJ47771.1 - 0.42 9.7 9.0 0.42 9.6 9.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ47771.1 - 0.66 9.5 20.8 0.7 9.5 20.8 1.1 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ47771.1 - 1 9.6 24.2 1.6 9.0 24.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Glt_symporter PF03616.14 CDJ47771.1 - 1.1 7.9 3.4 1.3 7.6 3.4 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter FAM60A PF15396.6 CDJ47771.1 - 1.1 9.2 4.8 1.1 9.2 4.8 1.0 1 0 0 1 1 1 0 Protein Family FAM60A R_equi_Vir PF05526.11 CDJ47771.1 - 1.2 8.9 11.5 1.4 8.8 11.5 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Suf PF05843.14 CDJ47771.1 - 1.8 8.5 12.8 1.9 8.4 12.8 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM199X PF15814.5 CDJ47771.1 - 3.1 6.8 10.4 3.5 6.6 10.4 1.0 1 0 0 1 1 1 0 Protein family FAM199X TFIIA PF03153.13 CDJ47771.1 - 4.1 7.3 27.3 4.5 7.1 27.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ47771.1 - 5.3 7.7 17.7 7.2 7.2 17.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AIF_C PF14721.6 CDJ47771.1 - 6 7.2 7.2 7.1 7.0 7.2 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term BAF1_ABF1 PF04684.13 CDJ47771.1 - 6.8 5.6 12.3 7.5 5.5 12.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Dehydrin PF00257.19 CDJ47771.1 - 7.3 7.1 7.6 8.5 6.9 7.6 1.1 1 0 0 1 1 1 0 Dehydrin Spore_coat_CotO PF14153.6 CDJ47771.1 - 7.5 6.4 17.6 8.4 6.3 17.6 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.17 CDJ47771.1 - 8.9 5.0 10.9 9.5 4.9 10.9 1.0 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ47772.1 - 0.02 13.8 0.2 0.02 13.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Fusion_gly PF00523.18 CDJ47772.1 - 0.058 11.6 0.5 0.077 11.2 0.5 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 LptF_LptG PF03739.14 CDJ47772.1 - 0.4 9.5 3.2 0.57 9.0 3.2 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG TFIIA PF03153.13 CDJ47772.1 - 0.53 10.2 20.2 0.76 9.7 20.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mrpl_C PF18502.1 CDJ47772.1 - 4.3 7.7 11.1 15 5.9 11.1 1.8 1 1 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain DUF4148 PF13663.6 CDJ47772.1 - 4.3 7.6 12.4 9.1 6.5 0.5 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) ANAPC_CDC26 PF10471.9 CDJ47772.1 - 7.6 7.4 24.5 0.37 11.6 5.6 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4378 PF14309.6 CDJ47773.1 - 3.5 8.0 6.7 1.7 9.0 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) TctA PF01970.16 CDJ47775.1 - 0.016 13.9 0.8 0.018 13.8 0.8 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family BAF1_ABF1 PF04684.13 CDJ47775.1 - 6 5.8 45.0 7 5.6 45.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.8 CDJ47777.1 - 0.012 15.2 25.5 0.014 15.0 25.5 1.0 1 0 0 1 1 1 0 Spt20 family UPF0560 PF10577.9 CDJ47777.1 - 0.031 12.8 12.3 0.036 12.6 12.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 V_ATPase_I PF01496.19 CDJ47777.1 - 0.051 11.5 7.3 0.051 11.5 7.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FYDLN_acid PF09538.10 CDJ47777.1 - 0.055 14.2 4.9 0.058 14.1 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4820 PF16091.5 CDJ47777.1 - 0.056 12.8 7.6 0.055 12.8 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3381 PF11861.8 CDJ47777.1 - 0.073 12.9 11.3 0.074 12.9 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF2722 PF10846.8 CDJ47777.1 - 0.085 11.8 20.8 0.088 11.7 20.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med3 PF11593.8 CDJ47777.1 - 0.093 11.9 15.1 0.11 11.6 15.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TMEM51 PF15345.6 CDJ47777.1 - 0.14 12.0 8.6 0.15 11.8 8.6 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 FAM176 PF14851.6 CDJ47777.1 - 0.14 11.8 6.0 0.14 11.8 6.0 1.1 1 0 0 1 1 1 0 FAM176 family DUF3408 PF11888.8 CDJ47777.1 - 0.15 12.2 8.7 0.15 12.2 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) GNAT_acetyltr_2 PF13718.6 CDJ47777.1 - 0.19 11.1 4.4 0.2 11.1 4.4 1.0 1 0 0 1 1 1 0 GNAT acetyltransferase 2 TFIIA PF03153.13 CDJ47777.1 - 0.2 11.7 19.2 0.2 11.6 19.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ47777.1 - 0.23 12.5 12.0 0.27 12.2 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF1501 PF07394.12 CDJ47777.1 - 0.24 10.4 9.3 0.28 10.2 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF3371 PF11851.8 CDJ47777.1 - 0.3 12.2 9.6 0.31 12.1 9.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) WRNPLPNID PF15017.6 CDJ47777.1 - 0.34 11.8 9.2 0.44 11.5 9.2 1.2 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Med15 PF09606.10 CDJ47777.1 - 0.36 9.5 16.9 0.33 9.6 16.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MMR1 PF08505.10 CDJ47777.1 - 0.36 11.1 10.0 0.36 11.1 10.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SPG4 PF17325.2 CDJ47777.1 - 0.39 11.8 7.9 0.46 11.6 7.9 1.0 1 0 0 1 1 1 0 Stationary phase protein 4 Tim54 PF11711.8 CDJ47777.1 - 0.44 9.3 8.8 0.46 9.2 8.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 CDJ47777.1 - 0.45 9.9 9.7 0.46 9.9 9.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF5327 PF17261.2 CDJ47777.1 - 0.56 11.0 14.6 0.73 10.6 14.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5327) DUF4746 PF15928.5 CDJ47777.1 - 0.6 9.5 7.6 0.62 9.4 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CobT PF06213.12 CDJ47777.1 - 0.71 9.2 14.3 0.72 9.2 14.3 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4770 PF15994.5 CDJ47777.1 - 0.73 10.0 8.9 0.76 10.0 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DDHD PF02862.17 CDJ47777.1 - 0.9 9.7 6.7 0.93 9.6 6.7 1.0 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.13 CDJ47777.1 - 1 9.1 6.4 1 9.1 6.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM150 PF15129.6 CDJ47777.1 - 1.1 9.5 7.3 1.1 9.4 7.3 1.1 1 0 0 1 1 1 0 FAM150 family MAJIN PF15077.6 CDJ47777.1 - 1.4 8.7 6.6 1.6 8.5 6.6 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Presenilin PF01080.17 CDJ47777.1 - 1.6 7.4 9.6 1.6 7.4 9.6 1.0 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 CDJ47777.1 - 1.8 7.3 4.4 1.8 7.3 4.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CLN3 PF02487.17 CDJ47777.1 - 1.8 7.5 5.6 1.7 7.6 5.6 1.0 1 0 0 1 1 1 0 CLN3 protein TERB2 PF15101.6 CDJ47777.1 - 1.9 8.5 11.9 2 8.4 11.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ureide_permease PF07168.11 CDJ47777.1 - 1.9 7.2 4.7 1.9 7.1 4.7 1.0 1 0 0 1 1 1 0 Ureide permease DUF3464 PF11947.8 CDJ47777.1 - 1.9 8.2 11.2 2.2 8.0 11.2 1.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Neur_chan_memb PF02932.16 CDJ47777.1 - 2.1 8.3 4.6 2.1 8.4 4.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PepSY_TM PF03929.16 CDJ47777.1 - 2.4 7.8 3.3 2.3 7.8 3.3 1.0 1 0 0 1 1 1 0 PepSY-associated TM region DUF4407 PF14362.6 CDJ47777.1 - 2.6 7.3 8.3 2.6 7.3 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CPSF100_C PF13299.6 CDJ47777.1 - 2.6 8.2 8.5 2.8 8.1 8.5 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AIF_C PF14721.6 CDJ47777.1 - 2.6 8.4 6.7 3 8.2 6.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Connexin PF00029.19 CDJ47777.1 - 3.1 7.5 6.6 3.2 7.5 6.6 1.0 1 0 0 1 1 1 0 Connexin Suf PF05843.14 CDJ47777.1 - 3.7 7.5 10.4 3.6 7.5 10.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MscS_TM PF12794.7 CDJ47777.1 - 5.1 5.8 8.6 5.6 5.7 8.6 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF775 PF05603.12 CDJ47777.1 - 5.4 6.5 10.5 6.1 6.3 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Androgen_recep PF02166.16 CDJ47777.1 - 5.7 5.7 22.3 5.8 5.6 22.3 1.0 1 0 0 1 1 1 0 Androgen receptor EIIBC-GUT_N PF03612.14 CDJ47777.1 - 6.1 6.5 9.5 6.8 6.4 9.5 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4175 PF13779.6 CDJ47777.1 - 6.2 4.6 18.9 6.2 4.6 18.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Serinc PF03348.15 CDJ47777.1 - 7 5.5 5.2 6.6 5.5 5.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) OATP PF03137.20 CDJ47777.1 - 7.3 4.8 5.7 7.5 4.7 5.7 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Activator_LAG-3 PF11498.8 CDJ47777.1 - 9.2 5.1 28.6 9.8 5.0 28.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Band_3_cyto PF07565.13 CDJ47778.1 - 0.0089 15.9 3.5 0.0089 15.9 3.5 4.5 4 1 0 4 4 4 2 Band 3 cytoplasmic domain LMBR1 PF04791.16 CDJ47778.1 - 1.9 7.3 17.7 0.17 10.8 7.7 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein TFIIF_alpha PF05793.12 CDJ47779.1 - 0.00019 20.2 35.1 0.00019 20.2 35.1 2.7 2 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PWWP PF00855.17 CDJ47779.1 - 0.00033 21.0 0.0 0.00033 21.0 0.0 4.8 4 2 0 4 4 4 1 PWWP domain APG9 PF04109.16 CDJ47779.1 - 0.17 10.8 0.8 0.26 10.2 0.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg9 PCNA_N PF00705.18 CDJ47781.1 - 1.7e-45 153.8 2.3 2e-40 137.4 1.0 2.8 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CDJ47781.1 - 1.8e-12 47.6 0.4 1.3e-11 44.8 0.2 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CDJ47781.1 - 1.1e-05 25.0 0.0 2.3e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Rad9 Auxin_canalis PF05703.11 CDJ47782.1 - 0.0018 18.2 21.4 0.0018 18.2 21.4 4.8 3 1 1 4 4 4 1 Auxin canalisation Caldesmon PF02029.15 CDJ47782.1 - 0.018 13.8 63.8 0.033 13.0 63.8 1.4 1 0 0 1 1 1 0 Caldesmon Pribosyltran PF00156.27 CDJ47783.1 - 0.00071 19.1 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CDC45 PF02724.14 CDJ47783.1 - 0.0049 15.2 17.6 0.006 14.9 17.6 1.0 1 0 0 1 1 1 1 CDC45-like protein Lin-8 PF03353.15 CDJ47783.1 - 0.023 14.3 23.7 0.028 14.0 23.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2828 PF11443.8 CDJ47783.1 - 0.024 12.7 14.2 0.027 12.6 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Plasmodium_Vir PF05795.11 CDJ47783.1 - 0.035 13.5 7.5 0.039 13.4 7.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein V_ATPase_I PF01496.19 CDJ47783.1 - 0.04 11.8 15.8 0.045 11.7 15.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Caldesmon PF02029.15 CDJ47783.1 - 0.063 12.0 24.2 0.071 11.9 24.2 1.2 1 0 0 1 1 1 0 Caldesmon DUF572 PF04502.13 CDJ47783.1 - 0.088 12.4 21.9 0.12 12.0 21.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SLC12 PF03522.15 CDJ47783.1 - 0.12 11.4 20.8 0.13 11.3 20.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 CDJ47783.1 - 0.21 10.5 12.2 0.24 10.3 12.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Draxin PF15550.6 CDJ47783.1 - 0.21 11.4 16.6 0.26 11.1 16.6 1.1 1 0 0 1 1 1 0 Draxin PAT1 PF09770.9 CDJ47783.1 - 0.25 9.6 37.2 0.3 9.3 37.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4471 PF14740.6 CDJ47783.1 - 0.34 10.1 12.0 0.41 9.8 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Baculo_PP31 PF05311.11 CDJ47783.1 - 0.37 10.2 11.5 0.63 9.5 11.5 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) NPR3 PF03666.13 CDJ47783.1 - 0.37 9.5 18.3 0.43 9.3 18.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GREB1 PF15782.5 CDJ47783.1 - 0.42 7.7 18.4 0.44 7.6 18.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 CDJ47783.1 - 0.59 8.9 15.6 0.65 8.8 15.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Afi1 PF07792.12 CDJ47783.1 - 0.71 10.4 23.7 1.1 9.8 23.7 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SID-1_RNA_chan PF13965.6 CDJ47783.1 - 0.86 7.9 6.4 0.99 7.7 6.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF-3_zeta PF05091.12 CDJ47783.1 - 0.9 8.4 26.9 1.3 8.0 26.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TRAP_alpha PF03896.16 CDJ47783.1 - 0.93 8.6 12.0 1.3 8.2 12.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_S64 PF08192.11 CDJ47783.1 - 1 7.8 15.2 1.2 7.6 15.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4746 PF15928.5 CDJ47783.1 - 1 8.7 18.7 1.6 8.0 18.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF5523 PF17661.1 CDJ47783.1 - 1 9.0 24.3 1.5 8.5 24.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Cellulose_synt PF03552.14 CDJ47783.1 - 1.2 7.6 8.2 1.4 7.3 8.2 1.1 1 0 0 1 1 1 0 Cellulose synthase GPCR_chapero_1 PF11904.8 CDJ47783.1 - 1.3 8.4 11.8 1.5 8.2 11.8 1.3 1 0 0 1 1 1 0 GPCR-chaperone Otopetrin PF03189.13 CDJ47783.1 - 1.4 7.7 7.2 1.5 7.6 7.2 1.3 1 0 0 1 1 1 0 Otopetrin CRT10 PF08728.10 CDJ47783.1 - 1.4 6.9 8.9 1.6 6.8 8.9 1.0 1 0 0 1 1 1 0 CRT10 SAPS PF04499.15 CDJ47783.1 - 1.6 7.5 16.9 1.7 7.3 16.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MMR1 PF08505.10 CDJ47783.1 - 1.6 8.9 23.6 2.3 8.4 23.6 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Endostatin PF06482.11 CDJ47783.1 - 2 7.8 18.7 2.8 7.3 18.7 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Serinc PF03348.15 CDJ47783.1 - 2 7.2 10.9 3.7 6.4 10.9 1.6 1 0 0 1 1 1 0 Serine incorporator (Serinc) Dapper PF15268.6 CDJ47783.1 - 2 7.2 27.0 2.4 6.9 27.0 1.0 1 0 0 1 1 1 0 Dapper Hamartin PF04388.12 CDJ47783.1 - 2.5 6.7 19.3 2.7 6.6 19.3 1.1 1 0 0 1 1 1 0 Hamartin protein Paf1 PF03985.13 CDJ47783.1 - 2.6 6.9 32.0 3.5 6.5 32.0 1.1 1 0 0 1 1 1 0 Paf1 TT_ORF1 PF02956.14 CDJ47783.1 - 3.5 6.2 14.5 3.9 6.0 14.5 1.1 1 0 0 1 1 1 0 TT viral orf 1 Hid1 PF12722.7 CDJ47783.1 - 4.5 5.3 23.5 5.3 5.0 23.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.6 CDJ47783.1 - 4.9 6.7 23.3 6.1 6.4 23.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF2126 PF09899.9 CDJ47783.1 - 5.7 4.9 12.9 6.8 4.6 12.9 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) FAM91_C PF14648.6 CDJ47783.1 - 7.8 5.2 12.1 10 4.9 12.1 1.1 1 0 0 1 1 1 0 FAM91 C-terminus SUIM_assoc PF16619.5 CDJ47784.1 - 0.02 15.0 0.0 0.02 15.0 0.0 3.5 1 1 2 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Med15 PF09606.10 CDJ47784.1 - 3 6.4 42.0 3.8 6.1 42.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MLANA PF14991.6 CDJ47786.1 - 2 8.7 6.0 6.6 7.0 6.0 1.9 1 0 0 1 1 1 0 Protein melan-A DUF1980 PF09323.10 CDJ47786.1 - 3.9 7.3 7.2 17 5.3 7.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RT_RNaseH_2 PF17919.1 CDJ47787.1 - 1.2e-18 67.0 0.0 3.5e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ47787.1 - 1.6e-11 44.1 0.0 2.8e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ47787.1 - 3.7e-09 36.8 0.0 7.8e-08 32.6 0.0 2.6 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase MRFAP1 PF15155.6 CDJ47787.1 - 0.072 13.6 0.2 0.22 12.0 0.1 1.8 2 0 0 2 2 2 0 MORF4 family-associated protein1 Ribosomal_S25 PF03297.15 CDJ47788.1 - 1.9e-39 134.0 0.8 2.1e-39 133.8 0.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 CDJ47788.1 - 0.022 14.6 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 MarR family AP2 PF00847.20 CDJ47790.1 - 6.9e-07 29.4 1.6 8.5e-06 25.9 0.5 7.0 10 0 0 10 10 10 2 AP2 domain CDK2AP PF09806.9 CDJ47790.1 - 0.0065 16.6 5.2 0.0065 16.6 5.2 12.2 4 3 6 12 12 12 1 Cyclin-dependent kinase 2-associated protein Sof1 PF04158.14 CDJ47792.1 - 3.7e-15 56.0 8.8 4.1e-15 55.8 8.8 1.0 1 0 0 1 1 1 1 Sof1-like domain Plasmodium_Vir PF05795.11 CDJ47793.1 - 0.0068 15.9 11.5 0.01 15.3 11.5 1.3 1 0 0 1 1 1 1 Plasmodium vivax Vir protein LAP1C PF05609.12 CDJ47793.1 - 2.7 7.0 40.5 3 6.8 40.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) AAA_18 PF13238.6 CDJ47794.1 - 2e-25 89.8 0.0 2.7e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CDJ47794.1 - 1.4e-08 35.3 0.1 4.3e-07 30.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ47794.1 - 2.3e-05 24.8 1.2 7e-05 23.3 1.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CDJ47794.1 - 2.8e-05 24.3 0.3 8.5e-05 22.7 0.0 2.2 2 1 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 CDJ47794.1 - 0.00013 21.9 0.1 0.00027 20.9 0.0 1.5 2 0 0 2 2 1 1 NTPase KTI12 PF08433.10 CDJ47794.1 - 0.00015 21.4 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ADK PF00406.22 CDJ47794.1 - 0.00016 21.8 1.6 0.0051 16.9 0.0 2.9 2 1 2 4 4 3 1 Adenylate kinase AAA_22 PF13401.6 CDJ47794.1 - 0.00038 20.7 0.0 0.00066 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CDJ47794.1 - 0.00048 20.6 0.0 0.00082 19.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CDJ47794.1 - 0.00067 19.6 0.0 0.001 19.0 0.0 1.5 1 1 0 1 1 1 1 NACHT domain dNK PF01712.19 CDJ47794.1 - 0.00078 19.4 0.2 0.15 11.9 0.0 2.1 1 1 0 2 2 2 1 Deoxynucleoside kinase MeaB PF03308.16 CDJ47794.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 CDJ47794.1 - 0.0013 19.1 0.0 0.0062 16.9 0.0 2.0 3 0 0 3 3 2 1 RNA helicase Viral_helicase1 PF01443.18 CDJ47794.1 - 0.0023 17.7 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 CDJ47794.1 - 0.0024 17.6 0.0 0.0052 16.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 CDJ47794.1 - 0.0039 17.3 0.0 0.091 12.9 0.0 2.3 2 1 1 3 3 3 1 Shikimate kinase AAA_5 PF07728.14 CDJ47794.1 - 0.0054 16.7 0.0 0.023 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 CDJ47794.1 - 0.0094 15.3 0.0 0.035 13.5 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_14 PF13173.6 CDJ47794.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.5 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 CDJ47794.1 - 0.016 15.0 0.1 0.087 12.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.12 CDJ47794.1 - 0.016 15.0 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ParA PF10609.9 CDJ47794.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Cytidylate_kin PF02224.18 CDJ47794.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase IstB_IS21 PF01695.17 CDJ47794.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 CDJ47794.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 CDJ47794.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 CDJ47794.1 - 0.033 14.1 0.0 0.081 12.8 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_7 PF12775.7 CDJ47794.1 - 0.048 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 CDJ47794.1 - 0.049 13.3 0.1 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.6 CDJ47794.1 - 0.05 13.8 1.9 0.067 13.4 0.0 2.2 2 1 2 4 4 1 0 AAA domain DUF2075 PF09848.9 CDJ47794.1 - 0.054 12.7 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 CDJ47794.1 - 0.072 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.22 CDJ47794.1 - 0.087 12.4 1.6 0.44 10.1 0.0 2.3 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 CDJ47794.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 CDJ47794.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 CDJ47794.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF5427 PF10310.9 CDJ47795.1 - 0.096 11.6 14.8 0.1 11.5 14.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) TFIIA PF03153.13 CDJ47795.1 - 0.11 12.5 24.4 0.11 12.4 24.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ47795.1 - 0.16 12.6 20.8 0.22 12.2 20.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ47795.1 - 0.48 10.0 25.0 0.7 9.5 25.0 1.2 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ47795.1 - 0.59 10.4 24.1 0.015 15.6 5.2 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Neur_chan_memb PF02932.16 CDJ47795.1 - 0.78 9.8 9.5 1.1 9.3 9.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.6 CDJ47795.1 - 0.93 9.4 12.8 1.3 9.0 12.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.12 CDJ47795.1 - 2.4 7.9 8.7 2.9 7.6 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.15 CDJ47795.1 - 2.5 7.6 11.2 2.9 7.4 11.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2076 PF09849.9 CDJ47795.1 - 2.6 8.0 28.1 10 6.1 22.6 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Ndc1_Nup PF09531.10 CDJ47795.1 - 3.3 6.3 9.2 3.1 6.4 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 CDJ47795.1 - 3.7 7.4 12.7 4.2 7.3 12.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ47797.1 - 0.0055 16.4 35.1 0.006 16.2 35.1 1.2 1 0 0 1 1 1 1 Spt20 family Pinin_SDK_memA PF04696.13 CDJ47797.1 - 0.28 11.2 28.0 0.34 11.0 28.0 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region SpoIIP PF07454.11 CDJ47797.1 - 0.44 10.0 15.5 0.46 9.9 15.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Afi1 PF07792.12 CDJ47797.1 - 0.93 10.0 12.3 1 9.8 12.3 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MMR1 PF08505.10 CDJ47797.1 - 1.3 9.2 18.7 1.4 9.1 18.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TERB2 PF15101.6 CDJ47797.1 - 1.3 9.0 21.3 1.5 8.8 21.3 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4647 PF15504.6 CDJ47797.1 - 1.8 7.6 17.8 1.7 7.7 17.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) EPL1 PF10513.9 CDJ47797.1 - 1.9 8.9 16.2 2.4 8.5 16.2 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF4746 PF15928.5 CDJ47797.1 - 2.1 7.7 13.5 2.1 7.7 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DDRGK PF09756.9 CDJ47797.1 - 2.1 7.9 25.2 2.4 7.7 25.2 1.1 1 0 0 1 1 1 0 DDRGK domain TFIIA PF03153.13 CDJ47797.1 - 2.3 8.1 41.5 2.4 8.1 41.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 CDJ47797.1 - 2.4 7.8 13.5 3.1 7.5 13.5 1.2 1 0 0 1 1 1 0 FAM176 family Band_3_cyto PF07565.13 CDJ47797.1 - 3.8 7.3 14.3 3.7 7.3 14.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BORG_CEP PF14957.6 CDJ47797.1 - 3.9 8.7 10.5 4.1 8.6 10.5 1.2 1 0 0 1 1 1 0 Cdc42 effector Tim54 PF11711.8 CDJ47797.1 - 4 6.1 16.6 4.2 6.0 16.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PTPRCAP PF15713.5 CDJ47797.1 - 4.2 7.7 23.6 5.4 7.3 23.6 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FAM91_C PF14648.6 CDJ47797.1 - 4.4 6.0 7.6 4 6.2 7.6 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Membralin PF09746.9 CDJ47797.1 - 5.1 6.0 9.3 5.2 6.0 9.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF4638 PF15472.6 CDJ47797.1 - 5.5 6.7 14.6 5.7 6.6 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) YABBY PF04690.13 CDJ47797.1 - 6.1 7.4 13.8 6.5 7.3 13.8 1.2 1 0 0 1 1 1 0 YABBY protein Paf1 PF03985.13 CDJ47797.1 - 6.1 5.7 21.6 6.8 5.6 21.6 1.1 1 0 0 1 1 1 0 Paf1 NST1 PF13945.6 CDJ47797.1 - 7.4 6.6 24.1 7.8 6.5 24.1 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Gti1_Pac2 PF09729.9 CDJ47797.1 - 7.9 6.5 14.9 9.1 6.3 14.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family TFB6 PF17110.5 CDJ47797.1 - 8 6.2 10.0 8.5 6.1 10.0 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sec62 PF03839.16 CDJ47797.1 - 8.1 5.9 12.9 9 5.7 12.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 CDJ47797.1 - 8.4 6.1 14.4 8.6 6.0 14.4 1.1 1 0 0 1 1 1 0 Connexin DDHD PF02862.17 CDJ47797.1 - 8.5 6.5 16.2 11 6.1 16.2 1.3 1 0 0 1 1 1 0 DDHD domain CLN3 PF02487.17 CDJ47797.1 - 9.3 5.2 13.8 9 5.2 13.8 1.1 1 0 0 1 1 1 0 CLN3 protein PPL5 PF18168.1 CDJ47797.1 - 9.3 5.4 13.5 9.6 5.4 13.5 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF1980 PF09323.10 CDJ47797.1 - 9.5 6.1 10.9 11 5.9 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) UPF0560 PF10577.9 CDJ47797.1 - 9.8 4.5 22.8 9.7 4.5 22.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FAM150 PF15129.6 CDJ47797.1 - 10 6.3 14.0 13 6.0 14.0 1.3 1 0 0 1 1 1 0 FAM150 family NAM-associated PF14303.6 CDJ47798.1 - 0.077 13.7 0.0 0.077 13.7 0.0 4.1 2 2 2 4 4 4 0 No apical meristem-associated C-terminal domain TFIIA PF03153.13 CDJ47800.1 - 0.0021 18.1 5.5 0.0026 17.8 5.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Secretin_N_2 PF07655.13 CDJ47800.1 - 0.026 15.1 16.7 0.036 14.6 6.0 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain SARAF PF06682.12 CDJ47800.1 - 0.029 14.0 3.7 0.042 13.5 3.7 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4179 PF13786.6 CDJ47800.1 - 0.051 14.0 3.7 2.1 8.9 0.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4179) SPX PF03105.19 CDJ47800.1 - 0.11 12.4 9.0 0.15 12.0 9.0 1.2 1 0 0 1 1 1 0 SPX domain stn_TNFRSF12A PF12191.8 CDJ47800.1 - 0.18 12.0 0.2 0.18 12.0 0.2 2.5 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Filament_head PF04732.14 CDJ47800.1 - 0.18 12.7 28.8 1.9 9.4 13.4 2.5 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region DUF3446 PF11928.8 CDJ47800.1 - 1.6 9.1 40.0 0.16 12.3 11.8 3.4 3 0 0 3 3 3 0 Early growth response N-terminal domain PAP1 PF08601.10 CDJ47800.1 - 2.6 7.7 16.0 3.7 7.2 16.0 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 SUZ PF12752.7 CDJ47800.1 - 5.1 7.9 15.0 1.1 10.0 1.9 2.9 3 0 0 3 3 3 0 SUZ domain DUF508 PF04370.12 CDJ47800.1 - 6.9 6.4 16.1 4.9 6.9 6.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Apt1 PF10351.9 CDJ47800.1 - 8 5.2 13.9 14 4.4 14.0 1.4 1 1 0 1 1 1 0 Golgi-body localisation protein domain DUF4776 PF16003.5 CDJ47801.1 - 1.9 7.4 16.6 2 7.3 16.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Chorion_2 PF03964.15 CDJ47801.1 - 2.6 8.9 31.7 0.33 11.8 18.7 2.1 1 1 1 2 2 2 0 Chorion family 2 DUF1387 PF07139.11 CDJ47801.1 - 4 7.1 19.2 4.9 6.8 19.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SLC12 PF03522.15 CDJ47801.1 - 5 6.0 21.0 6 5.8 21.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF1676 PF07898.13 CDJ47801.1 - 5.6 7.0 7.9 7.3 6.6 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) PEX11 PF05648.14 CDJ47801.1 - 8.3 5.8 14.0 4.8 6.6 5.5 2.1 1 1 1 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) MFS_1 PF07690.16 CDJ47802.1 - 0.00011 21.2 14.6 0.00011 21.2 14.6 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily IATP PF04568.12 CDJ47802.1 - 0.0011 19.3 4.1 0.0011 19.3 4.1 2.4 2 1 1 3 3 3 1 Mitochondrial ATPase inhibitor, IATP MID_MedPIWI PF18296.1 CDJ47802.1 - 0.36 10.6 5.3 0.54 10.0 5.3 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Presenilin PF01080.17 CDJ47802.1 - 0.86 8.3 9.2 1.6 7.4 9.2 1.4 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 CDJ47802.1 - 1.7 7.5 3.8 2.4 7.0 3.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SR-25 PF10500.9 CDJ47802.1 - 3.3 7.3 19.7 6.2 6.4 19.7 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF572 PF04502.13 CDJ47802.1 - 3.4 7.2 9.5 5 6.6 9.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CFIA_Pcf11 PF11526.8 CDJ47802.1 - 7.1 7.2 14.7 1.3 9.5 4.6 2.5 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 DUF2040 PF09745.9 CDJ47803.1 - 5.6e-14 52.2 6.8 1.6e-11 44.3 0.1 4.0 4 0 0 4 4 4 2 Coiled-coil domain-containing protein 55 (DUF2040) PRK PF00485.18 CDJ47803.1 - 0.6 9.8 3.0 0.52 10.0 0.3 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family XRN_N PF03159.18 CDJ47804.1 - 6.1e-45 153.5 4.1 1.8e-40 138.9 0.5 9.7 7 4 0 7 7 7 3 XRN 5'-3' exonuclease N-terminus Spt20 PF12090.8 CDJ47804.1 - 0.0057 16.3 14.9 0.0057 16.3 14.9 11.1 7 3 2 9 9 9 3 Spt20 family CNDH2_C PF16858.5 CDJ47804.1 - 0.29 11.0 0.0 0.29 11.0 0.0 6.2 4 2 0 4 4 4 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Aldo_ket_red PF00248.21 CDJ47805.1 - 8.9e-12 44.8 0.0 3.5e-08 33.0 0.0 2.6 2 1 0 2 2 2 2 Aldo/keto reductase family Antibiotic_NAT PF02522.14 CDJ47805.1 - 0.093 12.5 0.9 0.13 12.1 0.2 1.6 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase FAM199X PF15814.5 CDJ47806.1 - 0.0018 17.4 8.3 0.002 17.3 8.3 1.0 1 0 0 1 1 1 1 Protein family FAM199X TFIIA PF03153.13 CDJ47806.1 - 0.0065 16.5 31.0 0.0071 16.4 31.0 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 CDJ47806.1 - 0.028 14.4 2.2 0.028 14.5 2.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A BAF1_ABF1 PF04684.13 CDJ47806.1 - 0.037 13.1 12.3 0.041 12.9 12.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor eIF-3_zeta PF05091.12 CDJ47806.1 - 0.062 12.3 8.4 0.059 12.3 8.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SelP_N PF04592.14 CDJ47806.1 - 0.064 12.6 11.6 0.08 12.3 11.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Connexin PF00029.19 CDJ47806.1 - 0.1 12.3 2.6 0.11 12.3 2.6 1.1 1 0 0 1 1 1 0 Connexin Suf PF05843.14 CDJ47806.1 - 0.14 12.1 10.6 0.14 12.1 10.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Tim54 PF11711.8 CDJ47806.1 - 0.17 10.7 5.1 0.17 10.6 5.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.9 CDJ47806.1 - 0.23 9.7 17.9 0.23 9.7 17.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ47806.1 - 0.26 10.0 11.5 0.27 9.9 11.5 1.0 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ47806.1 - 0.36 10.9 5.3 0.36 10.8 5.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 CDJ47806.1 - 0.37 10.9 7.4 0.39 10.8 7.4 1.1 1 0 0 1 1 1 0 DDHD domain GREB1 PF15782.5 CDJ47806.1 - 0.44 7.6 9.8 0.51 7.4 9.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EOS1 PF12326.8 CDJ47806.1 - 0.64 9.9 1.9 0.63 9.9 1.9 1.2 1 0 0 1 1 1 0 N-glycosylation protein Ctr PF04145.15 CDJ47806.1 - 0.79 10.3 2.7 0.94 10.1 2.7 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF726 PF05277.12 CDJ47806.1 - 0.91 8.4 4.2 0.97 8.3 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) RR_TM4-6 PF06459.12 CDJ47806.1 - 0.96 9.2 9.7 0.97 9.2 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.15 CDJ47806.1 - 1 8.2 3.5 1.1 8.2 3.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Tic110 PF16940.5 CDJ47806.1 - 1.1 7.7 16.1 1.2 7.5 16.1 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter MMR1 PF08505.10 CDJ47806.1 - 1.3 9.2 10.3 1.4 9.1 10.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4834 PF16118.5 CDJ47806.1 - 1.6 9.8 10.5 2.4 9.2 10.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ47806.1 - 1.8 6.4 9.0 1.9 6.3 9.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1980 PF09323.10 CDJ47806.1 - 2.7 7.9 6.4 3.2 7.6 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Med15 PF09606.10 CDJ47806.1 - 2.8 6.5 30.9 4.3 5.9 30.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.8 CDJ47806.1 - 3.1 6.7 33.8 3.7 6.4 33.8 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Rtf2 PF04641.12 CDJ47806.1 - 3.6 6.9 11.5 5 6.4 11.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger OATP PF03137.20 CDJ47806.1 - 3.8 5.7 4.9 4.6 5.4 4.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CLN3 PF02487.17 CDJ47806.1 - 4.1 6.4 5.5 5 6.1 5.5 1.3 1 0 0 1 1 1 0 CLN3 protein eIF_4EBP PF05456.11 CDJ47806.1 - 4.5 7.2 8.9 7.1 6.6 8.9 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) EF-hand_1 PF00036.32 CDJ47807.1 - 1.2e-21 74.6 5.0 2e-05 23.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ47807.1 - 1.6e-20 73.3 3.6 2.5e-09 37.5 0.7 3.4 2 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ47807.1 - 1.5e-19 68.2 2.0 2.2e-05 24.0 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ47807.1 - 4e-18 64.0 4.4 5.7e-05 22.4 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDJ47807.1 - 6.9e-10 38.6 4.1 0.04 13.8 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ47807.1 - 2.7e-05 24.4 0.4 0.18 12.1 0.1 3.1 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Unstab_antitox PF09720.10 CDJ47807.1 - 1.5 8.9 6.3 3.5 7.7 0.1 3.5 2 1 1 3 3 3 0 Putative addiction module component Hydrolase PF00702.26 CDJ47808.1 - 4e-14 53.4 1.6 7e-06 26.5 0.0 3.6 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Macoilin PF09726.9 CDJ47808.1 - 3.5e-05 22.6 26.9 3.5e-05 22.6 26.9 6.3 6 2 0 6 6 6 1 Macoilin family DUF4698 PF15769.5 CDJ47808.1 - 0.00011 21.4 2.3 0.00011 21.4 2.3 7.7 8 3 0 9 9 9 1 Domain of unknown function (DUF4698) CNDH2_C PF16858.5 CDJ47808.1 - 0.003 17.5 9.7 0.003 17.5 9.7 5.8 6 0 0 6 6 6 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term HAD PF12710.7 CDJ47808.1 - 0.0045 17.4 0.2 1.4 9.2 0.0 3.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase SPX PF03105.19 CDJ47808.1 - 0.0079 16.2 10.2 0.0079 16.2 10.2 6.8 5 2 1 6 6 6 1 SPX domain RskA PF10099.9 CDJ47808.1 - 0.0099 16.2 2.1 0.0099 16.2 2.1 10.2 3 2 6 9 9 9 3 Anti-sigma-K factor rskA Hydrolase_3 PF08282.12 CDJ47808.1 - 0.22 11.2 0.0 0.22 11.2 0.0 3.0 5 0 0 5 5 5 0 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ47808.1 - 0.62 9.6 0.0 0.62 9.6 0.0 2.7 2 0 0 2 2 2 0 E1-E2 ATPase ApbA PF02558.16 CDJ47809.1 - 0.039 13.6 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ANAPC_CDC26 PF10471.9 CDJ47809.1 - 0.06 14.2 0.2 0.06 14.2 0.2 6.4 7 1 0 7 7 7 0 Anaphase-promoting complex APC subunit CDC26 HemN_C PF06969.16 CDJ47809.1 - 0.31 11.1 3.9 0.19 11.8 0.7 2.3 2 0 0 2 2 2 0 HemN C-terminal domain Hormone_1 PF00103.20 CDJ47809.1 - 0.33 10.7 3.7 0.99 9.1 3.7 1.8 1 0 0 1 1 1 0 Somatotropin hormone family Glyco_hydro_67N PF03648.14 CDJ47809.1 - 0.79 10.0 2.7 1.3 9.4 0.9 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus SAS-6_N PF16531.5 CDJ47810.1 - 1e-06 29.2 0.0 1e-06 29.2 0.0 2.9 2 1 0 2 2 2 1 Centriolar protein SAS N-terminal RskA PF10099.9 CDJ47810.1 - 0.0077 16.5 7.6 0.0077 16.5 7.6 4.9 2 1 1 3 3 3 1 Anti-sigma-K factor rskA Mito_carr PF00153.27 CDJ47810.1 - 0.66 9.9 0.0 0.66 9.9 0.0 3.1 3 1 1 4 4 4 0 Mitochondrial carrier protein IMUP PF15761.5 CDJ47811.1 - 0.035 14.8 3.0 0.035 14.8 3.0 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF5427 PF10310.9 CDJ47811.1 - 0.35 9.8 23.6 0.43 9.5 23.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF1249 PF06853.12 CDJ47811.1 - 0.77 9.8 10.6 0.78 9.8 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1249) SR-25 PF10500.9 CDJ47811.1 - 0.87 9.2 22.5 0.2 11.2 12.6 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Med15 PF09606.10 CDJ47811.1 - 1.2 7.7 54.1 1.4 7.5 54.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal YL1 PF05764.13 CDJ47811.1 - 2 8.5 22.1 2.3 8.2 22.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 CDJ47811.1 - 2.5 7.8 15.9 3.6 7.2 15.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CSG2 PF16965.5 CDJ47811.1 - 6.4 5.6 7.8 8 5.3 7.8 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Apt1 PF10351.9 CDJ47813.1 - 0.091 11.6 6.1 0.093 11.6 6.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Miga PF10265.9 CDJ47813.1 - 6.9 5.5 12.0 11 4.9 12.0 1.2 1 0 0 1 1 1 0 Mitoguardin PAT1 PF09770.9 CDJ47814.1 - 3.5 5.8 55.0 0.7 8.1 18.6 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 FPV060 PF17614.2 CDJ47815.1 - 0.16 11.4 0.8 0.34 10.3 0.8 1.5 1 0 0 1 1 1 0 Viral CC-type chemokine Herpes_pp85 PF04637.12 CDJ47815.1 - 0.42 9.0 4.2 0.86 7.9 4.2 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RskA PF10099.9 CDJ47817.1 - 9e-05 22.8 14.8 0.00092 19.5 14.5 2.4 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF1180 PF06679.12 CDJ47817.1 - 0.012 16.1 8.0 0.012 16.1 8.0 3.0 1 1 1 2 2 1 0 Protein of unknown function (DUF1180) Tic110 PF16940.5 CDJ47817.1 - 0.024 13.2 1.0 0.027 13.0 1.0 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter FAM91_C PF14648.6 CDJ47817.1 - 0.037 12.9 6.6 0.044 12.6 6.6 1.2 1 0 0 1 1 1 0 FAM91 C-terminus Lys_export PF03956.13 CDJ47817.1 - 0.072 12.6 0.3 0.1 12.1 0.3 1.2 1 0 0 1 1 1 0 Lysine exporter LysO Serinc PF03348.15 CDJ47817.1 - 0.47 9.3 10.1 0.58 9.0 10.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) PAT1 PF09770.9 CDJ47817.1 - 0.47 8.7 24.7 0.57 8.4 24.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ABC2_membrane_3 PF12698.7 CDJ47817.1 - 0.52 9.4 1.7 0.76 8.8 1.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Utp14 PF04615.13 CDJ47817.1 - 0.72 8.4 15.0 0.91 8.0 15.0 1.1 1 0 0 1 1 1 0 Utp14 protein YajC PF02699.15 CDJ47817.1 - 0.9 9.5 0.1 0.9 9.5 0.1 3.3 2 1 0 2 2 1 0 Preprotein translocase subunit Het-C PF07217.11 CDJ47817.1 - 1.3 7.4 5.5 1.7 7.1 5.5 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF4064 PF13273.6 CDJ47817.1 - 2.2 8.6 8.8 18 5.7 1.0 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4131 PF13567.6 CDJ47817.1 - 3.5 7.2 7.9 17 5.0 7.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) GREB1 PF15782.5 CDJ47817.1 - 5.1 4.1 26.4 6.4 3.7 26.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CSG2 PF16965.5 CDJ47817.1 - 5.5 5.8 11.5 1 8.2 5.5 1.9 1 1 0 2 2 2 0 Ceramide synthase regulator DUF1345 PF07077.11 CDJ47817.1 - 6.7 6.4 7.0 0.82 9.4 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) SID-1_RNA_chan PF13965.6 CDJ47817.1 - 6.8 5.0 9.0 11 4.3 8.2 1.9 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 CDJ47818.1 - 0.033 12.5 59.4 0.038 12.3 59.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RskA PF10099.9 CDJ47819.1 - 0.0046 17.3 15.5 0.0046 17.3 15.5 2.7 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ47819.1 - 0.018 16.0 0.1 0.037 15.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MAJIN PF15077.6 CDJ47820.1 - 0.029 14.2 6.7 0.035 13.9 6.7 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Macoilin PF09726.9 CDJ47820.1 - 0.14 10.7 9.8 0.16 10.5 9.8 1.0 1 0 0 1 1 1 0 Macoilin family BNR_3 PF13859.6 CDJ47820.1 - 0.39 9.9 3.7 0.49 9.6 3.7 1.1 1 0 0 1 1 1 0 BNR repeat-like domain Neur_chan_memb PF02932.16 CDJ47820.1 - 1.3 9.1 9.8 1.5 8.8 9.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ47820.1 - 1.8 8.5 34.7 2.6 7.9 34.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ47820.1 - 3.8 6.4 13.0 4.3 6.3 13.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Suf PF05843.14 CDJ47820.1 - 4.8 7.1 16.1 6.4 6.7 16.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GREB1 PF15782.5 CDJ47820.1 - 4.8 4.2 16.4 5.6 4.0 16.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Exonuc_VII_L PF02601.15 CDJ47820.1 - 7.1 6.1 16.5 8.2 5.9 16.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Presenilin PF01080.17 CDJ47820.1 - 8.4 5.0 16.8 9.6 4.8 16.8 1.1 1 0 0 1 1 1 0 Presenilin MMM1 PF10296.9 CDJ47820.1 - 8.7 5.3 10.2 19 4.2 10.1 1.6 1 1 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Utp14 PF04615.13 CDJ47821.1 - 0.26 9.8 46.4 0.028 13.0 24.0 2.1 1 1 1 2 2 2 0 Utp14 protein FlbT PF07378.11 CDJ47821.1 - 4.8 7.3 8.4 0.87 9.7 0.2 2.7 2 0 0 2 2 2 0 Flagellar protein FlbT Ank_2 PF12796.7 CDJ47822.1 - 8.1e-26 90.4 7.9 2.1e-08 34.6 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ47822.1 - 6.9e-24 83.9 6.9 1.4e-08 35.1 0.0 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CDJ47822.1 - 2.1e-16 59.6 17.4 0.0012 19.1 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 CDJ47822.1 - 4.5e-15 54.2 5.8 0.0028 18.0 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 CDJ47822.1 - 5.9e-12 45.6 5.7 0.053 13.8 0.0 5.0 3 1 0 4 4 4 4 Ankyrin repeats (many copies) SDF PF00375.18 CDJ47822.1 - 5.7 5.8 12.0 3.6 6.5 0.4 3.6 3 1 0 3 3 3 0 Sodium:dicarboxylate symporter family Activator_LAG-3 PF11498.8 CDJ47823.1 - 0.00013 21.1 13.8 0.00013 21.1 13.8 4.1 3 1 1 4 4 4 1 Transcriptional activator LAG-3 DP PF08781.10 CDJ47825.1 - 0.0034 17.3 10.6 0.0039 17.1 10.6 1.0 1 0 0 1 1 1 1 Transcription factor DP EMP24_GP25L PF01105.24 CDJ47825.1 - 0.05 13.5 4.0 0.054 13.4 4.0 1.0 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Helitron_like_N PF14214.6 CDJ47825.1 - 0.053 13.7 4.0 0.058 13.6 4.0 1.1 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus RskA PF10099.9 CDJ47825.1 - 0.055 13.8 4.3 0.061 13.6 4.3 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Glyco_transf_8 PF01501.20 CDJ47825.1 - 0.058 12.9 1.2 0.063 12.8 1.2 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 8 DUF4199 PF13858.6 CDJ47825.1 - 0.087 13.2 2.3 0.092 13.1 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Dfp1_Him1_M PF08630.10 CDJ47825.1 - 0.11 12.8 3.1 0.12 12.6 3.1 1.1 1 0 0 1 1 1 0 Dfp1/Him1, central region DcuA_DcuB PF03605.14 CDJ47825.1 - 0.13 11.1 0.6 0.14 11.1 0.6 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter EIIBC-GUT_N PF03612.14 CDJ47825.1 - 0.29 10.8 2.5 0.31 10.7 2.5 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ABC2_membrane_2 PF12679.7 CDJ47825.1 - 0.71 9.1 2.8 0.74 9.0 2.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein TERB2 PF15101.6 CDJ47825.1 - 3.3 7.7 11.0 3.9 7.5 11.0 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spc24 PF08286.11 CDJ47825.1 - 3.9 7.8 11.8 4.6 7.5 11.8 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 FAM222A PF15258.6 CDJ47825.1 - 8.2 5.4 14.1 9.8 5.2 14.1 1.0 1 0 0 1 1 1 0 Protein family of FAM222A EIF4E-T PF10477.9 CDJ47825.1 - 8.5 5.1 13.9 9.4 4.9 13.9 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E zf-MYND PF01753.18 CDJ47826.1 - 0.00037 20.5 3.9 0.00037 20.5 3.9 1.9 2 0 0 2 2 2 1 MYND finger Spt20 PF12090.8 CDJ47826.1 - 0.0073 16.0 13.0 0.0073 16.0 13.0 4.9 3 1 0 3 3 3 1 Spt20 family SR-25 PF10500.9 CDJ47827.1 - 2.9e-05 23.8 28.7 4e-05 23.3 28.7 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ47827.1 - 0.0012 19.1 38.1 0.0012 19.1 38.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF755) AF-4 PF05110.13 CDJ47827.1 - 0.0021 16.3 24.9 0.0024 16.0 24.9 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein MPM1 PF17234.2 CDJ47827.1 - 0.0032 17.7 13.6 0.0037 17.6 13.6 1.2 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 TFIIA PF03153.13 CDJ47827.1 - 0.007 16.4 29.1 0.0079 16.2 29.1 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ47827.1 - 0.0081 15.8 36.6 0.0099 15.5 36.6 1.1 1 0 0 1 1 1 1 Spt20 family GREB1 PF15782.5 CDJ47827.1 - 0.017 12.3 19.0 0.018 12.2 19.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ47827.1 - 0.032 13.8 17.7 0.034 13.7 17.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TMEM51 PF15345.6 CDJ47827.1 - 0.036 13.9 17.3 0.037 13.9 17.3 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 BAT2_N PF07001.11 CDJ47827.1 - 0.039 14.4 19.5 0.042 14.3 19.5 1.1 1 0 0 1 1 1 0 BAT2 N-terminus CDK2AP PF09806.9 CDJ47827.1 - 0.043 13.9 17.2 0.048 13.7 17.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4692 PF15763.5 CDJ47827.1 - 0.051 14.0 12.0 0.057 13.9 12.0 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Mem_trans PF03547.18 CDJ47827.1 - 0.054 11.9 9.1 0.054 11.9 9.1 1.0 1 0 0 1 1 1 0 Membrane transport protein Slu7 PF11708.8 CDJ47827.1 - 0.056 13.2 10.2 0.066 12.9 10.2 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF1635 PF07795.11 CDJ47827.1 - 0.062 13.2 19.2 0.071 13.0 19.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Sporozoite_P67 PF05642.11 CDJ47827.1 - 0.063 11.4 6.1 0.075 11.1 6.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PNISR PF15996.5 CDJ47827.1 - 0.089 13.1 16.3 0.1 12.8 16.3 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR EPL1 PF10513.9 CDJ47827.1 - 0.12 12.7 13.4 0.15 12.5 13.4 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like SRP-alpha_N PF04086.13 CDJ47827.1 - 0.13 12.2 15.0 0.14 12.1 15.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2722 PF10846.8 CDJ47827.1 - 0.14 11.1 30.9 0.2 10.6 30.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SPX PF03105.19 CDJ47827.1 - 0.14 12.1 14.8 0.14 12.1 14.8 1.0 1 0 0 1 1 1 0 SPX domain CPSF100_C PF13299.6 CDJ47827.1 - 0.18 12.0 9.1 0.21 11.8 9.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Macoilin PF09726.9 CDJ47827.1 - 0.19 10.2 16.8 0.21 10.1 16.8 1.1 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 CDJ47827.1 - 0.23 11.2 17.9 0.24 11.1 17.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.9 CDJ47827.1 - 0.25 10.2 18.7 0.26 10.1 18.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM176 PF14851.6 CDJ47827.1 - 0.26 11.0 5.8 0.29 10.8 5.8 1.3 1 0 0 1 1 1 0 FAM176 family Utp14 PF04615.13 CDJ47827.1 - 0.26 9.8 16.4 0.3 9.6 16.4 1.0 1 0 0 1 1 1 0 Utp14 protein DUF1180 PF06679.12 CDJ47827.1 - 0.27 11.6 7.0 0.28 11.6 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) BORG_CEP PF14957.6 CDJ47827.1 - 0.27 12.4 13.3 0.3 12.2 13.3 1.2 1 0 0 1 1 1 0 Cdc42 effector Menin PF05053.13 CDJ47827.1 - 0.41 9.0 11.7 0.42 8.9 11.7 1.0 1 0 0 1 1 1 0 Menin SpoIIP PF07454.11 CDJ47827.1 - 0.41 10.1 11.5 0.44 9.9 11.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ47827.1 - 0.42 9.5 17.8 0.47 9.4 17.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Roughex PF06020.11 CDJ47827.1 - 0.42 9.7 12.9 0.49 9.4 12.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Afi1 PF07792.12 CDJ47827.1 - 0.45 11.0 10.3 0.53 10.8 10.3 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Herpes_pp85 PF04637.12 CDJ47827.1 - 0.46 8.9 6.9 0.51 8.7 6.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Stig1 PF04885.13 CDJ47827.1 - 0.5 10.9 13.1 0.57 10.7 13.1 1.1 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF4746 PF15928.5 CDJ47827.1 - 0.51 9.7 4.8 0.53 9.7 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MMR1 PF08505.10 CDJ47827.1 - 0.53 10.5 21.9 0.57 10.4 21.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Gti1_Pac2 PF09729.9 CDJ47827.1 - 0.57 10.3 13.2 0.67 10.0 13.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family PepSY_TM PF03929.16 CDJ47827.1 - 0.58 9.8 2.5 0.54 9.9 2.5 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Connexin PF00029.19 CDJ47827.1 - 0.66 9.7 8.2 0.72 9.6 8.2 1.2 1 0 0 1 1 1 0 Connexin Plasmodium_Vir PF05795.11 CDJ47827.1 - 0.72 9.2 11.5 0.79 9.1 11.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF913 PF06025.12 CDJ47827.1 - 0.73 8.7 9.9 0.86 8.5 9.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MAP65_ASE1 PF03999.12 CDJ47827.1 - 0.74 8.4 19.5 0.73 8.5 19.5 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Dicty_REP PF05086.12 CDJ47827.1 - 0.8 7.6 9.8 0.89 7.4 9.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CLN3 PF02487.17 CDJ47827.1 - 0.84 8.6 10.9 0.87 8.6 10.9 1.1 1 0 0 1 1 1 0 CLN3 protein NST1 PF13945.6 CDJ47827.1 - 0.86 9.7 22.8 0.99 9.5 22.8 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator GTA_holin_3TM PF11351.8 CDJ47827.1 - 0.95 10.0 6.2 1.2 9.7 6.2 1.3 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release ALMT PF11744.8 CDJ47827.1 - 1 8.1 13.4 0.98 8.2 13.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ47827.1 - 1 8.3 15.1 1.2 8.1 15.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ47827.1 - 1.2 7.9 19.1 1.3 7.8 19.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 CDJ47827.1 - 1.2 7.0 23.7 1.2 7.0 23.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF908 PF06012.12 CDJ47827.1 - 1.2 8.5 17.7 1.4 8.2 17.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Sec62 PF03839.16 CDJ47827.1 - 1.3 8.5 9.1 1.5 8.3 9.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 UPF0565 PF10561.9 CDJ47827.1 - 1.3 8.2 8.3 1.3 8.2 8.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF4554 PF15091.6 CDJ47827.1 - 1.3 7.8 14.2 1.6 7.6 14.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Peroxin-3 PF04882.12 CDJ47827.1 - 1.4 7.9 19.5 1.5 7.7 19.5 1.1 1 0 0 1 1 1 0 Peroxin-3 Maf1 PF09174.10 CDJ47827.1 - 1.4 9.1 11.2 1.9 8.6 11.2 1.2 1 0 0 1 1 1 0 Maf1 regulator Ndc1_Nup PF09531.10 CDJ47827.1 - 1.4 7.5 16.6 1.4 7.5 16.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Med24_N PF11277.8 CDJ47827.1 - 1.6 6.7 14.4 1.6 6.6 14.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Tim54 PF11711.8 CDJ47827.1 - 1.6 7.4 9.3 1.9 7.2 9.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RskA PF10099.9 CDJ47827.1 - 1.9 8.8 9.2 2.3 8.5 9.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2370 PF10176.9 CDJ47827.1 - 1.9 8.0 6.4 2.5 7.7 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) BRF1 PF07741.13 CDJ47827.1 - 2 8.8 12.7 3 8.2 12.7 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain V_ATPase_I PF01496.19 CDJ47827.1 - 2.2 6.1 13.5 2.4 6.0 13.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPR3 PF03666.13 CDJ47827.1 - 2.5 6.8 16.5 2.6 6.7 16.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_S64 PF08192.11 CDJ47827.1 - 2.7 6.4 19.3 2.9 6.3 19.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF853 PF05872.12 CDJ47827.1 - 2.7 6.5 9.6 3.1 6.3 9.6 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PAT1 PF09770.9 CDJ47827.1 - 3.4 5.8 22.9 3.8 5.7 22.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 XRN_M PF17846.1 CDJ47827.1 - 3.6 6.5 8.8 3.8 6.4 8.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Sin_N PF04801.13 CDJ47827.1 - 4.1 6.5 21.6 4.5 6.4 21.6 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region Hid1 PF12722.7 CDJ47827.1 - 4.3 5.4 17.0 4.4 5.3 17.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Membralin PF09746.9 CDJ47827.1 - 4.4 6.3 8.8 4.7 6.1 8.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein Otopetrin PF03189.13 CDJ47827.1 - 4.4 6.0 10.8 5 5.8 10.8 1.1 1 0 0 1 1 1 0 Otopetrin Paramyxo_ncap PF00973.19 CDJ47827.1 - 4.8 6.0 10.7 4.9 5.9 10.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4228 PF14009.6 CDJ47827.1 - 4.8 7.5 13.7 6.6 7.1 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) CAML PF14963.6 CDJ47827.1 - 5.1 7.1 11.5 5.5 7.0 11.5 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF4199 PF13858.6 CDJ47827.1 - 5.8 7.3 5.2 6.6 7.1 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF702 PF05142.12 CDJ47827.1 - 5.9 7.4 21.4 7.9 6.9 21.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF702) MMU163 PF17119.5 CDJ47827.1 - 6.4 5.8 9.1 9.9 5.2 9.1 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF4407 PF14362.6 CDJ47827.1 - 6.6 6.0 13.0 7.9 5.7 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NEMP PF10225.9 CDJ47827.1 - 7 6.2 11.8 7.6 6.1 11.8 1.1 1 0 0 1 1 1 0 NEMP family UPF0560 PF10577.9 CDJ47827.1 - 7.1 5.0 21.1 8.6 4.7 21.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CobT PF06213.12 CDJ47827.1 - 7.2 5.9 22.6 8.9 5.6 22.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Rrn6 PF10214.9 CDJ47827.1 - 7.4 4.9 29.5 7.6 4.9 29.5 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Miga PF10265.9 CDJ47827.1 - 7.9 5.3 18.6 8.4 5.2 18.6 1.0 1 0 0 1 1 1 0 Mitoguardin RR_TM4-6 PF06459.12 CDJ47827.1 - 8.6 6.1 14.0 10 5.9 14.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Folate_carrier PF01770.18 CDJ47827.1 - 9.9 4.8 6.9 10 4.7 6.9 1.2 1 0 0 1 1 1 0 Reduced folate carrier ATP_bind_3 PF01171.20 CDJ47828.1 - 2.8e-07 30.5 17.6 0.025 14.3 0.0 4.9 4 1 1 5 5 5 3 PP-loop family TLD PF07534.16 CDJ47829.1 - 1.7e-10 41.2 0.0 3.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 TLD DUF4746 PF15928.5 CDJ47829.1 - 0.14 11.6 10.2 0.74 9.2 10.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) RT_RNaseH_2 PF17919.1 CDJ47831.1 - 1e-13 51.2 0.0 2.8e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ47831.1 - 2.6e-09 36.9 0.0 4e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ47831.1 - 2.9e-07 30.7 0.1 1.2e-05 25.5 0.0 2.4 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase Aminotran_1_2 PF00155.21 CDJ47832.1 - 1.8e-18 66.8 6.6 3.6e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II RskA PF10099.9 CDJ47832.1 - 0.0014 19.0 22.4 0.0024 18.2 22.4 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ47832.1 - 0.0025 17.9 26.9 0.0025 17.9 26.9 1.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Glyco_hydro_9 PF00759.19 CDJ47832.1 - 0.018 14.5 12.3 0.021 14.3 12.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Hydin_ADK PF17213.3 CDJ47832.1 - 0.034 14.4 14.5 1.2 9.4 11.8 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DivIC PF04977.15 CDJ47832.1 - 0.38 10.5 12.9 2.9 7.7 12.1 2.5 2 0 0 2 2 2 0 Septum formation initiator Pex14_N PF04695.13 CDJ47832.1 - 0.44 11.2 22.4 0.12 13.1 16.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FHIPEP PF00771.20 CDJ47832.1 - 0.58 8.6 6.9 0.76 8.2 6.9 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4834 PF16118.5 CDJ47832.1 - 0.75 10.8 6.7 0.71 10.9 4.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Roughex PF06020.11 CDJ47832.1 - 1.2 8.2 7.7 1.6 7.8 7.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein UPF0560 PF10577.9 CDJ47832.1 - 2.5 6.5 15.6 3.3 6.1 15.6 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0560 HAUS6_N PF14661.6 CDJ47832.1 - 3.1 7.3 16.0 5 6.6 16.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2232 PF09991.9 CDJ47832.1 - 4.2 6.5 4.5 5.9 6.0 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4820 PF16091.5 CDJ47832.1 - 4.5 6.6 11.4 9.1 5.6 11.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) Peptidase_S15 PF02129.18 CDJ47832.1 - 5.3 6.6 11.5 8.4 5.9 11.5 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PIN_8 PF18476.1 CDJ47832.1 - 6.3 6.6 10.1 9.9 5.9 10.1 1.2 1 0 0 1 1 1 0 PIN like domain XRN_M PF17846.1 CDJ47832.1 - 6.8 5.5 10.2 9.4 5.1 10.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Spore_coat_CotO PF14153.6 CDJ47832.1 - 7.6 6.4 17.2 11 5.9 17.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Spt20 PF12090.8 CDJ47832.1 - 8.2 6.0 29.8 0.026 14.1 20.6 1.6 2 0 0 2 2 1 0 Spt20 family Suf PF05843.14 CDJ47832.1 - 8.8 6.2 18.5 0.38 10.7 12.9 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1645 PF07816.11 CDJ47836.1 - 0.0017 19.0 4.7 0.0017 19.0 4.7 5.3 6 2 0 6 6 6 1 Protein of unknown function (DUF1645) DUF755 PF05501.11 CDJ47836.1 - 0.016 15.5 20.7 0.016 15.5 20.7 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF755) SUIM_assoc PF16619.5 CDJ47836.1 - 0.35 10.9 68.1 0.038 14.1 3.7 6.7 7 0 0 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ47836.1 - 1.9 8.1 40.8 1.4 8.5 3.9 3.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein AKAP7_NLS PF10469.9 CDJ47837.1 - 6.7e-09 35.9 2.7 1.5e-08 34.8 2.7 1.5 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain DUF2722 PF10846.8 CDJ47837.1 - 0.0069 15.4 20.6 0.032 13.2 1.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ47837.1 - 0.0097 15.5 30.6 0.2 11.3 8.6 2.2 2 0 0 2 2 2 2 Spt20 family MPM1 PF17234.2 CDJ47837.1 - 0.051 13.8 8.9 0.074 13.3 0.6 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF853 PF05872.12 CDJ47837.1 - 0.28 9.7 10.4 0.12 10.9 1.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) eIF-3_zeta PF05091.12 CDJ47837.1 - 0.54 9.2 11.2 0.71 8.8 1.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ47837.1 - 0.54 11.3 14.7 4.5 8.3 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SARAF PF06682.12 CDJ47837.1 - 0.67 9.5 11.2 2.4 7.7 1.2 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis ANAPC_CDC26 PF10471.9 CDJ47837.1 - 0.83 10.5 37.8 0.43 11.4 12.5 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 TERB2 PF15101.6 CDJ47837.1 - 2.1 8.4 11.2 1.5 8.8 2.4 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 BRF1 PF07741.13 CDJ47837.1 - 2.7 8.4 9.2 2.1 8.8 0.4 3.1 3 0 0 3 3 3 0 Brf1-like TBP-binding domain NUC194 PF08163.12 CDJ47837.1 - 2.9 6.7 6.4 0.14 11.0 1.0 1.5 2 0 0 2 2 2 0 NUC194 domain EOS1 PF12326.8 CDJ47837.1 - 4.7 7.1 10.2 31 4.5 10.1 2.1 1 1 0 1 1 1 0 N-glycosylation protein Med3 PF11593.8 CDJ47837.1 - 5.4 6.1 35.7 1.8 7.7 0.5 3.2 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal UPF0240 PF06784.11 CDJ47837.1 - 6.3 6.8 9.4 3.2 7.8 1.4 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0240) PEHE PF15275.6 CDJ47837.1 - 6.7 7.4 14.1 5 7.8 4.9 2.3 2 0 0 2 2 2 0 PEHE domain UPF0560 PF10577.9 CDJ47837.1 - 8.8 4.7 17.8 5.2 5.4 5.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Presenilin PF01080.17 CDJ47837.1 - 9.6 4.9 10.7 4.2 6.0 0.5 2.1 2 0 0 2 2 2 0 Presenilin NPR1_interact PF15699.5 CDJ47838.1 - 1 10.0 34.8 0.93 10.1 3.1 3.7 3 0 0 3 3 3 0 NPR1 interacting DUF4179 PF13786.6 CDJ47840.1 - 1.4 9.5 0.0 1.4 9.5 0.0 5.9 5 3 0 5 5 5 0 Domain of unknown function (DUF4179) Apt1 PF10351.9 CDJ47841.1 - 0.36 9.6 13.4 0.67 8.7 13.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 CDJ47841.1 - 0.53 8.6 7.5 0.86 7.9 7.5 1.3 1 0 0 1 1 1 0 Menin TFIIA PF03153.13 CDJ47841.1 - 0.66 9.9 30.8 0.92 9.4 30.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.11 CDJ47841.1 - 2 6.8 7.9 3 6.2 7.9 1.3 1 0 0 1 1 1 0 Peptidase family S64 Miga PF10265.9 CDJ47841.1 - 3 6.7 11.0 5 6.0 11.0 1.3 1 0 0 1 1 1 0 Mitoguardin HSD3 PF15244.6 CDJ47841.1 - 5 6.5 12.3 9.4 5.6 12.3 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Presenilin PF01080.17 CDJ47842.1 - 0.1 11.3 9.9 0.14 10.9 9.9 1.1 1 0 0 1 1 1 0 Presenilin Thg1C PF14413.6 CDJ47842.1 - 0.43 10.7 10.7 0.3 11.3 1.4 2.1 2 0 0 2 2 2 0 Thg1 C terminal domain FlaG PF03646.15 CDJ47842.1 - 0.85 9.8 19.3 0.88 9.8 5.9 2.2 2 0 0 2 2 2 0 FlaG protein Pex14_N PF04695.13 CDJ47842.1 - 1.1 9.9 22.7 0.59 10.8 8.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EOS1 PF12326.8 CDJ47842.1 - 4.1 7.3 6.2 3.8 7.4 0.4 2.1 2 0 0 2 2 2 0 N-glycosylation protein TERB2 PF15101.6 CDJ47842.1 - 4.3 7.3 20.9 0.38 10.8 5.2 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4199 PF13858.6 CDJ47842.1 - 4.7 7.6 11.0 11 6.4 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) PigN PF04987.14 CDJ47842.1 - 5.9 5.6 8.8 6.9 5.4 0.9 2.0 2 0 0 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) Med15 PF09606.10 CDJ47842.1 - 6.7 5.3 43.1 9.9 4.7 43.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Agouti PF05039.12 CDJ47842.1 - 7 7.4 9.0 11 6.8 0.4 2.2 2 0 0 2 2 2 0 Agouti protein PAT1 PF09770.9 CDJ47842.1 - 7.3 4.7 26.5 9.7 4.3 26.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPW_WPC PF09717.10 CDJ47843.1 - 5.1e-17 62.6 8.2 1.4e-14 54.8 2.7 2.4 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) DUF2722 PF10846.8 CDJ47843.1 - 0.23 10.4 4.8 0.26 10.2 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SLBP_RNA_bind PF15247.6 CDJ47844.1 - 2e-08 34.2 0.2 2e-08 34.2 0.2 3.5 3 1 1 4 4 4 1 Histone RNA hairpin-binding protein RNA-binding domain DUF4366 PF14283.6 CDJ47845.1 - 0.9 9.6 3.2 0.89 9.6 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF4179 PF13786.6 CDJ47845.1 - 2.6 8.6 9.5 1.1 9.8 0.4 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) RskA PF10099.9 CDJ47845.1 - 8.1 6.7 40.5 6.1 7.1 9.3 2.8 1 1 2 3 3 3 0 Anti-sigma-K factor rskA GBP PF02263.19 CDJ47846.1 - 3.9e-10 39.4 0.2 5e-06 26.0 0.0 5.4 5 2 0 6 6 6 2 Guanylate-binding protein, N-terminal domain RskA PF10099.9 CDJ47846.1 - 3e-05 24.4 0.0 3e-05 24.4 0.0 9.5 4 3 2 7 7 7 2 Anti-sigma-K factor rskA Caldesmon PF02029.15 CDJ47846.1 - 0.00026 19.9 22.3 0.00026 19.9 22.3 4.3 4 2 0 4 4 4 2 Caldesmon SpoIIIAH PF12685.7 CDJ47846.1 - 0.0014 18.5 1.7 0.0014 18.5 1.7 4.8 4 2 0 4 4 4 1 SpoIIIAH-like protein DUF3295 PF11702.8 CDJ47846.1 - 0.0033 16.9 4.7 0.0033 16.9 4.7 5.4 5 1 1 6 6 6 1 Protein of unknown function (DUF3295) DDHD PF02862.17 CDJ47846.1 - 0.0054 16.9 2.1 0.0054 16.9 2.1 6.7 2 1 1 5 5 5 1 DDHD domain ABC2_membrane_2 PF12679.7 CDJ47846.1 - 0.0076 15.6 0.0 0.0076 15.6 0.0 6.0 5 1 0 5 5 5 1 ABC-2 family transporter protein RAB3GAP2_N PF14655.6 CDJ47847.1 - 0.49 9.6 4.4 0.81 8.9 4.4 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.8 CDJ47847.1 - 0.71 9.4 16.2 0.035 13.7 10.5 1.6 2 0 0 2 2 2 0 Spt20 family RNase_H2_suC PF08615.11 CDJ47848.1 - 9.9e-06 25.8 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MCM_bind PF09739.9 CDJ47849.1 - 0.011 14.3 9.4 0.012 14.1 9.4 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Coilin_N PF15862.5 CDJ47849.1 - 0.014 15.2 11.0 0.019 14.7 11.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus YL1 PF05764.13 CDJ47849.1 - 0.016 15.3 12.5 0.017 15.2 12.5 1.0 1 0 0 1 1 1 0 YL1 nuclear protein CCDC106 PF15794.5 CDJ47849.1 - 0.031 14.0 14.0 0.04 13.6 14.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Velvet PF11754.8 CDJ47849.1 - 0.045 13.7 16.0 0.047 13.6 16.0 1.0 1 0 0 1 1 1 0 Velvet factor ASD2 PF08687.11 CDJ47849.1 - 0.059 12.9 12.2 0.065 12.8 12.2 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 V_ATPase_I PF01496.19 CDJ47849.1 - 0.06 11.3 8.4 0.064 11.2 8.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spore_coat_CotO PF14153.6 CDJ47849.1 - 0.067 13.1 11.6 0.071 13.0 11.6 1.0 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.12 CDJ47849.1 - 0.07 12.9 8.6 0.071 12.9 8.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.8 CDJ47849.1 - 0.098 11.8 23.5 0.13 11.3 23.5 1.2 1 0 0 1 1 1 0 SprA-related family Serinc PF03348.15 CDJ47849.1 - 0.12 11.3 5.8 0.12 11.3 5.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Suf PF05843.14 CDJ47849.1 - 0.13 12.3 14.5 0.13 12.2 14.5 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spem1 PF15670.5 CDJ47849.1 - 0.15 11.6 14.6 0.18 11.4 14.6 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 SelP_N PF04592.14 CDJ47849.1 - 0.16 11.3 16.8 0.2 11.0 16.8 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDK2AP PF09806.9 CDJ47849.1 - 0.17 11.9 21.4 0.25 11.4 21.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein MID_MedPIWI PF18296.1 CDJ47849.1 - 0.2 11.4 15.2 0.25 11.1 15.2 1.1 1 0 0 1 1 1 0 MID domain of medPIWI zf-C2H2_3rep PF18868.1 CDJ47849.1 - 0.22 12.2 9.4 0.32 11.7 9.4 1.3 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats Zip PF02535.22 CDJ47849.1 - 0.26 10.5 10.9 0.27 10.4 10.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CSG2 PF16965.5 CDJ47849.1 - 0.28 10.1 6.9 0.29 10.0 6.9 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4820 PF16091.5 CDJ47849.1 - 0.29 10.5 10.2 0.43 9.9 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Bul1_C PF04426.12 CDJ47849.1 - 0.29 10.5 11.4 0.32 10.3 11.4 1.1 1 0 0 1 1 1 0 Bul1 C terminus Pex14_N PF04695.13 CDJ47849.1 - 0.3 11.7 21.1 0.39 11.3 21.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5427 PF10310.9 CDJ47849.1 - 0.51 9.2 16.4 0.56 9.1 16.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) FAM199X PF15814.5 CDJ47849.1 - 0.61 9.1 21.9 0.69 8.9 21.9 1.0 1 0 0 1 1 1 0 Protein family FAM199X RRT14 PF17075.5 CDJ47849.1 - 0.63 10.1 15.2 0.79 9.8 15.2 1.0 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 PI3K_1B_p101 PF10486.9 CDJ47849.1 - 0.67 7.7 15.8 0.72 7.6 15.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TCP PF03634.13 CDJ47849.1 - 0.71 10.4 18.0 0.89 10.1 18.0 1.1 1 0 0 1 1 1 0 TCP family transcription factor CCSAP PF15748.5 CDJ47849.1 - 0.76 9.9 21.0 0.92 9.6 21.0 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Bul1_N PF04425.12 CDJ47849.1 - 0.84 8.3 15.4 0.9 8.2 15.4 1.0 1 0 0 1 1 1 0 Bul1 N terminus Gti1_Pac2 PF09729.9 CDJ47849.1 - 0.92 9.6 12.8 1.1 9.3 12.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family TFIIA PF03153.13 CDJ47849.1 - 1.1 9.2 27.6 1.2 9.1 27.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EOS1 PF12326.8 CDJ47849.1 - 1.1 9.2 8.0 1.4 8.8 8.0 1.3 1 0 0 1 1 1 0 N-glycosylation protein rRNA_processing PF08524.11 CDJ47849.1 - 1.2 9.2 18.1 1.6 8.8 18.1 1.1 1 0 0 1 1 1 0 rRNA processing NPR3 PF03666.13 CDJ47849.1 - 1.4 7.6 18.8 1.6 7.4 18.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CLN3 PF02487.17 CDJ47849.1 - 1.6 7.6 7.7 1.7 7.6 7.7 1.1 1 0 0 1 1 1 0 CLN3 protein PPP4R2 PF09184.11 CDJ47849.1 - 1.9 8.0 11.7 2.1 7.9 11.7 1.0 1 0 0 1 1 1 0 PPP4R2 Peptidase_S64 PF08192.11 CDJ47849.1 - 1.9 6.9 17.6 2 6.8 17.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 DDHD PF02862.17 CDJ47849.1 - 2 8.5 13.8 2.9 8.0 13.8 1.3 1 0 0 1 1 1 0 DDHD domain EPL1 PF10513.9 CDJ47849.1 - 2.1 8.7 14.9 3.1 8.2 14.9 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like CobT PF06213.12 CDJ47849.1 - 2.3 7.5 16.9 2.9 7.2 16.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SR-25 PF10500.9 CDJ47849.1 - 2.5 7.7 39.9 5.4 6.6 39.9 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 CDJ47849.1 - 2.7 5.0 17.9 3 4.8 17.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCDC53 PF10152.9 CDJ47849.1 - 2.7 8.4 14.8 3.5 8.0 14.8 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Raftlin PF15250.6 CDJ47849.1 - 2.8 6.6 13.8 3.2 6.4 13.8 1.0 1 0 0 1 1 1 0 Raftlin Neur_chan_memb PF02932.16 CDJ47849.1 - 3.1 7.8 11.9 3.5 7.6 11.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOBP PF15279.6 CDJ47849.1 - 3.9 8.0 18.3 4.5 7.8 18.3 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein SMYLE_N PF18615.1 CDJ47849.1 - 4.1 6.9 16.0 4.8 6.6 16.0 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Kei1 PF08552.11 CDJ47849.1 - 5.2 6.9 12.3 6.3 6.6 12.3 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SLC12 PF03522.15 CDJ47849.1 - 5.3 5.9 13.2 6.1 5.8 13.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RSRP PF17069.5 CDJ47849.1 - 6 6.4 24.5 8.1 5.9 24.5 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CDC45 PF02724.14 CDJ47849.1 - 8.9 4.5 15.9 11 4.1 15.9 1.0 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.11 CDJ47849.1 - 9.1 4.4 13.2 9.4 4.4 13.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Presenilin PF01080.17 CDJ47849.1 - 9.2 4.9 22.8 11 4.7 22.8 1.0 1 0 0 1 1 1 0 Presenilin DUF3824 PF12868.7 CDJ47850.1 - 0.00028 21.6 12.0 0.00038 21.1 12.0 1.3 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) RSB_motif PF16294.5 CDJ47850.1 - 0.016 15.5 11.5 0.021 15.1 11.5 1.3 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif Miga PF10265.9 CDJ47850.1 - 0.028 13.4 5.0 0.03 13.3 5.0 1.0 1 0 0 1 1 1 0 Mitoguardin Pex14_N PF04695.13 CDJ47850.1 - 0.031 14.9 24.0 0.038 14.6 24.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NeuB PF03102.14 CDJ47850.1 - 0.052 13.0 11.5 0.063 12.7 11.5 1.1 1 0 0 1 1 1 0 NeuB family TFIIA PF03153.13 CDJ47850.1 - 0.052 13.5 39.2 0.061 13.3 39.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5523 PF17661.1 CDJ47850.1 - 0.071 12.8 13.6 0.086 12.5 13.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Cellulose_synt PF03552.14 CDJ47850.1 - 0.1 11.1 3.3 0.11 11.0 3.3 1.0 1 0 0 1 1 1 0 Cellulose synthase NARP1 PF12569.8 CDJ47850.1 - 0.1 11.5 16.6 0.12 11.3 16.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.12 CDJ47850.1 - 0.11 11.9 18.5 0.12 11.7 18.5 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Macoilin PF09726.9 CDJ47850.1 - 0.11 11.0 16.3 0.15 10.6 16.3 1.2 1 0 0 1 1 1 0 Macoilin family FAM60A PF15396.6 CDJ47850.1 - 0.11 12.5 13.8 0.15 12.1 13.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A MMR1 PF08505.10 CDJ47850.1 - 0.11 12.7 21.4 0.14 12.5 21.4 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein AF-4 PF05110.13 CDJ47850.1 - 0.15 10.1 23.6 0.17 10.0 23.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF913 PF06025.12 CDJ47850.1 - 0.15 11.0 6.9 0.17 10.8 6.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tim54 PF11711.8 CDJ47850.1 - 0.16 10.7 12.4 0.18 10.6 12.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BAF1_ABF1 PF04684.13 CDJ47850.1 - 0.18 10.8 20.7 0.23 10.5 20.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Stig1 PF04885.13 CDJ47850.1 - 0.21 12.0 13.4 0.29 11.6 13.4 1.2 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DDHD PF02862.17 CDJ47850.1 - 0.22 11.7 13.2 0.29 11.3 13.2 1.2 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 CDJ47850.1 - 0.23 11.5 14.0 0.26 11.3 14.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sin_N PF04801.13 CDJ47850.1 - 0.25 10.5 21.5 0.29 10.3 21.5 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Spore_coat_CotO PF14153.6 CDJ47850.1 - 0.27 11.2 22.6 0.33 10.9 22.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF4569 PF15133.6 CDJ47850.1 - 0.3 10.8 20.4 0.36 10.5 20.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) ALGX PF16822.5 CDJ47850.1 - 0.3 10.7 21.3 0.39 10.4 21.3 1.0 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX TERB2 PF15101.6 CDJ47850.1 - 0.31 11.1 18.8 0.42 10.6 18.8 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PAT1 PF09770.9 CDJ47850.1 - 0.39 8.9 31.3 0.43 8.8 31.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4045 PF13254.6 CDJ47850.1 - 0.4 10.3 14.2 0.44 10.1 14.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ribosomal_60s PF00428.19 CDJ47850.1 - 0.4 11.3 11.9 0.72 10.5 11.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4228 PF14009.6 CDJ47850.1 - 0.43 10.9 10.4 0.51 10.7 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) GREB1 PF15782.5 CDJ47850.1 - 0.45 7.6 18.0 0.49 7.5 18.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 CDJ47850.1 - 0.5 9.1 23.4 0.58 8.9 23.4 1.0 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ47850.1 - 0.5 9.3 17.0 0.57 9.1 17.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Hydin_ADK PF17213.3 CDJ47850.1 - 0.51 10.6 16.5 0.61 10.3 16.5 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CSG2 PF16965.5 CDJ47850.1 - 0.6 9.0 5.9 0.66 8.9 5.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4050 PF13259.6 CDJ47850.1 - 0.63 10.3 12.4 0.83 10.0 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) PPL5 PF18168.1 CDJ47850.1 - 0.65 9.2 13.6 0.75 9.0 13.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 SAPS PF04499.15 CDJ47850.1 - 0.7 8.6 11.9 0.75 8.5 11.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LAP1C PF05609.12 CDJ47850.1 - 0.79 8.7 19.2 0.91 8.5 19.2 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Zip PF02535.22 CDJ47850.1 - 0.81 8.8 17.9 0.91 8.7 17.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S64 PF08192.11 CDJ47850.1 - 0.83 8.1 16.2 0.95 7.9 16.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 DDRGK PF09756.9 CDJ47850.1 - 0.9 9.1 20.1 1.1 8.9 20.1 1.2 1 0 0 1 1 1 0 DDRGK domain Gti1_Pac2 PF09729.9 CDJ47850.1 - 0.91 9.6 16.3 1.1 9.3 16.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Lin-8 PF03353.15 CDJ47850.1 - 0.92 9.0 19.0 1 8.9 19.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Endostatin PF06482.11 CDJ47850.1 - 0.95 8.9 17.7 1.2 8.5 17.7 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin TRAP_alpha PF03896.16 CDJ47850.1 - 1.1 8.5 6.4 1.3 8.2 6.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RPN2_C PF18004.1 CDJ47850.1 - 1.1 9.2 14.1 1.4 8.8 14.1 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BORG_CEP PF14957.6 CDJ47850.1 - 1.3 10.2 11.8 1.7 9.8 11.8 1.2 1 0 0 1 1 1 0 Cdc42 effector CDC45 PF02724.14 CDJ47850.1 - 1.3 7.3 14.1 1.4 7.1 14.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Asp-B-Hydro_N PF05279.11 CDJ47850.1 - 1.5 8.9 13.5 1.7 8.6 13.5 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Connexin PF00029.19 CDJ47850.1 - 1.5 8.5 14.8 1.8 8.3 14.8 1.2 1 0 0 1 1 1 0 Connexin VIT1 PF01988.19 CDJ47850.1 - 1.5 8.6 7.0 1.8 8.4 7.0 1.2 1 0 0 1 1 1 0 VIT family Rrn6 PF10214.9 CDJ47850.1 - 1.9 6.9 19.0 2 6.8 19.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor eIF-3_zeta PF05091.12 CDJ47850.1 - 1.9 7.3 21.5 2.3 7.1 21.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ47850.1 - 2.1 6.2 19.5 2.3 6.0 19.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDK5_activator PF03261.15 CDJ47850.1 - 2.3 7.7 15.4 2.6 7.5 15.4 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Spc7_N PF15402.6 CDJ47850.1 - 2.3 6.4 14.7 2.5 6.2 14.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 VIR_N PF15912.5 CDJ47850.1 - 2.4 7.7 9.8 2.9 7.4 9.8 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF2126 PF09899.9 CDJ47850.1 - 2.5 6.0 12.1 2.7 5.9 12.1 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2464 PF10240.9 CDJ47850.1 - 2.7 7.5 9.5 3.2 7.3 9.5 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 Peptidase_U57 PF05582.12 CDJ47850.1 - 2.7 7.2 11.7 3.3 6.9 11.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Spem1 PF15670.5 CDJ47850.1 - 2.8 7.4 18.7 3.3 7.2 18.7 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 SelP_N PF04592.14 CDJ47850.1 - 2.9 7.3 37.4 4.3 6.7 37.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Raftlin PF15250.6 CDJ47850.1 - 3 6.5 15.0 3.5 6.3 15.0 1.0 1 0 0 1 1 1 0 Raftlin ALMT PF11744.8 CDJ47850.1 - 3.1 6.5 15.6 3.4 6.4 15.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SID-1_RNA_chan PF13965.6 CDJ47850.1 - 3.2 6.0 7.7 3.6 5.9 7.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PSI_PsaF PF02507.15 CDJ47850.1 - 3.9 7.3 6.6 5 6.9 6.6 1.1 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III WTX PF09422.10 CDJ47850.1 - 4.1 6.4 14.0 4.8 6.1 14.0 1.0 1 0 0 1 1 1 0 WTX protein Exonuc_VII_L PF02601.15 CDJ47850.1 - 4.1 6.9 18.6 4.6 6.7 18.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM176 PF14851.6 CDJ47850.1 - 4.3 7.0 10.7 5.8 6.6 10.7 1.3 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.12 CDJ47850.1 - 4.4 7.1 21.1 5.3 6.8 21.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 R_equi_Vir PF05526.11 CDJ47850.1 - 4.5 7.1 11.8 5.9 6.7 11.8 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein MAJIN PF15077.6 CDJ47850.1 - 4.9 6.9 12.2 5.7 6.7 12.2 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein YjbH PF06082.11 CDJ47850.1 - 5.1 5.8 11.0 5.6 5.6 11.0 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH eIF3_subunit PF08597.10 CDJ47850.1 - 5.2 6.9 23.1 6.4 6.6 23.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Velvet PF11754.8 CDJ47850.1 - 5.2 6.9 21.2 7 6.5 21.2 1.1 1 0 0 1 1 1 0 Velvet factor DUF1387 PF07139.11 CDJ47850.1 - 6.4 6.4 19.3 7.6 6.2 19.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Pannexin_like PF12534.8 CDJ47850.1 - 7 5.6 14.4 8.7 5.3 14.4 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Serinc PF03348.15 CDJ47850.1 - 7.3 5.4 10.3 8.5 5.2 10.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CLN3 PF02487.17 CDJ47850.1 - 7.9 5.4 14.4 9.1 5.2 14.4 1.1 1 0 0 1 1 1 0 CLN3 protein Ureide_permease PF07168.11 CDJ47850.1 - 9.4 4.9 9.5 11 4.6 9.5 1.1 1 0 0 1 1 1 0 Ureide permease Myosin_head PF00063.21 CDJ47851.1 - 0.0003 19.2 2.8 0.0034 15.7 0.0 2.6 3 0 0 3 3 3 2 Myosin head (motor domain) SPX PF03105.19 CDJ47851.1 - 1.6 8.6 34.4 0.0096 15.9 16.4 2.4 1 1 0 2 2 2 0 SPX domain BRF1 PF07741.13 CDJ47851.1 - 3.7 7.9 8.3 2 8.8 0.8 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Activator_LAG-3 PF11498.8 CDJ47852.1 - 0.019 14.0 46.4 0.025 13.5 46.4 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SOBP PF15279.6 CDJ47852.1 - 0.84 10.2 24.1 1.1 9.8 24.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2722 PF10846.8 CDJ47852.1 - 2.4 7.0 34.8 2.7 6.8 7.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ47853.1 - 0.0078 15.9 56.1 0.091 12.4 35.7 2.1 2 0 0 2 2 2 2 Spt20 family Spt20 PF12090.8 CDJ47854.1 - 0.035 13.7 23.8 0.27 10.8 12.7 2.1 2 0 0 2 2 2 0 Spt20 family DUF2076 PF09849.9 CDJ47854.1 - 0.1 12.6 20.6 0.24 11.4 5.6 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Connexin PF00029.19 CDJ47854.1 - 0.65 9.7 6.4 12 5.6 0.0 2.1 2 0 0 2 2 2 0 Connexin Coilin_N PF15862.5 CDJ47854.1 - 1.4 8.7 19.4 0.96 9.3 3.8 2.4 2 0 0 2 2 2 0 Coilin N-terminus CLN3 PF02487.17 CDJ47854.1 - 1.6 7.7 10.7 0.19 10.7 1.1 2.1 2 0 0 2 2 2 0 CLN3 protein Kei1 PF08552.11 CDJ47854.1 - 6.9 6.5 14.4 0.47 10.3 2.7 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 THRAP3_BCLAF1 PF15440.6 CDJ47857.1 - 0.0007 18.8 50.3 0.0007 18.8 50.3 2.1 2 0 0 2 2 2 1 THRAP3/BCLAF1 family TFIIA PF03153.13 CDJ47857.1 - 6.2 6.7 189.6 0.017 15.2 62.1 3.5 1 1 3 4 4 4 0 Transcription factor IIA, alpha/beta subunit RNA_lig_T4_1 PF09511.10 CDJ47858.1 - 0.21 11.4 6.4 0.41 10.5 2.4 2.3 2 1 0 2 2 2 0 RNA ligase Ank_2 PF12796.7 CDJ47859.1 - 3.7e-19 69.1 4.7 1.8e-09 38.0 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ47859.1 - 4.7e-16 58.9 3.6 2.1e-05 25.0 0.3 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ47859.1 - 4.2e-13 49.2 1.8 1.8e-06 28.1 0.1 4.8 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ47859.1 - 6.6e-12 45.3 7.3 8.3e-07 29.2 0.0 5.9 7 0 0 7 7 7 2 Ankyrin repeat Ank_3 PF13606.6 CDJ47859.1 - 6.8e-12 44.5 8.7 4.9e-06 26.5 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat TFIIA PF03153.13 CDJ47859.1 - 4.4 7.2 92.2 9.9 6.0 92.2 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ47861.1 - 0.001 18.7 26.3 0.001 18.7 26.3 2.6 1 1 2 3 3 3 1 Nuclear RNA-splicing-associated protein PAT1 PF09770.9 CDJ47861.1 - 0.012 14.0 24.9 0.012 14.0 24.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDK5_activator PF03261.15 CDJ47861.1 - 0.043 13.4 12.4 0.054 13.0 12.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Nop53 PF07767.11 CDJ47861.1 - 0.055 12.9 18.0 0.071 12.5 18.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Presenilin PF01080.17 CDJ47861.1 - 0.06 12.1 18.6 0.075 11.8 18.6 1.3 1 0 0 1 1 1 0 Presenilin TCP PF03634.13 CDJ47861.1 - 0.081 13.5 19.8 0.14 12.7 19.8 1.5 1 0 0 1 1 1 0 TCP family transcription factor CCSAP PF15748.5 CDJ47861.1 - 0.31 11.2 37.5 0.24 11.5 36.2 1.3 1 1 0 1 1 1 0 Centriole, cilia and spindle-associated SLC12 PF03522.15 CDJ47861.1 - 0.35 9.8 14.7 0.4 9.7 14.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ47861.1 - 0.38 10.8 13.8 0.52 10.3 13.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serglycin PF04360.12 CDJ47861.1 - 0.78 9.7 11.8 1.6 8.6 11.8 1.5 1 0 0 1 1 1 0 Serglycin Hid1 PF12722.7 CDJ47861.1 - 1.1 7.3 17.5 1.1 7.3 17.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4603 PF15376.6 CDJ47861.1 - 1.3 6.3 16.2 1.6 6.0 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) MCM_bind PF09739.9 CDJ47861.1 - 1.6 7.1 14.7 1.9 6.9 14.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RR_TM4-6 PF06459.12 CDJ47861.1 - 2.3 8.0 18.2 3.1 7.6 18.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOBP PF15279.6 CDJ47861.1 - 2.4 8.7 27.0 2.9 8.4 27.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Use1 PF09753.9 CDJ47861.1 - 2.8 7.6 17.6 3.9 7.1 17.6 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 GET2 PF08690.10 CDJ47861.1 - 3.5 7.2 15.2 4.1 7.0 15.2 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Lin-8 PF03353.15 CDJ47861.1 - 3.9 6.9 24.9 0.065 12.8 16.3 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 CDJ47861.1 - 4.2 4.4 25.1 5.2 4.0 25.1 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Tim54 PF11711.8 CDJ47861.1 - 6.2 5.5 16.2 8.3 5.1 16.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Otopetrin PF03189.13 CDJ47861.1 - 7.6 5.2 10.8 9.5 4.9 10.8 1.1 1 0 0 1 1 1 0 Otopetrin SR-25 PF10500.9 CDJ47862.1 - 0.013 15.1 48.4 0.026 14.1 15.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SMYLE_N PF18615.1 CDJ47862.1 - 1.3 8.5 29.2 1.7 8.1 29.2 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PBP_N PF17093.5 CDJ47862.1 - 4 7.7 12.7 5.7 7.2 12.2 1.5 1 1 0 1 1 1 0 Penicillin-binding protein N-terminus RskA PF10099.9 CDJ47863.1 - 0.0012 19.2 10.2 0.0012 19.2 10.2 2.2 1 1 0 2 2 2 1 Anti-sigma-K factor rskA DUF2232 PF09991.9 CDJ47863.1 - 0.22 10.7 0.1 0.28 10.3 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SR-25 PF10500.9 CDJ47864.1 - 0.00069 19.3 20.6 0.00069 19.3 20.6 9.5 6 1 3 9 9 9 6 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ47864.1 - 0.0017 18.7 8.9 0.0017 18.7 8.9 10.8 1 1 5 9 9 9 2 Anti-sigma-K factor rskA Fapy_DNA_glyco PF01149.24 CDJ47865.1 - 2.1 9.0 8.6 1.6 9.4 1.6 2.1 1 1 1 2 2 2 0 Formamidopyrimidine-DNA glycosylase N-terminal domain DUF1631 PF07793.11 CDJ47868.1 - 0.44 8.9 9.1 0.49 8.8 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) AF-4 PF05110.13 CDJ47868.1 - 1.2 7.1 13.9 1.1 7.3 13.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UCR_TM PF02921.14 CDJ47868.1 - 1.7 9.2 6.6 0.66 10.5 1.8 2.2 1 1 1 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region Myosin_head PF00063.21 CDJ47873.1 - 1.2e-13 50.2 1.7 1.2e-13 50.2 1.7 2.0 1 1 0 2 2 2 1 Myosin head (motor domain) DUF2076 PF09849.9 CDJ47873.1 - 0.00035 20.7 37.1 0.00035 20.7 37.1 5.9 2 1 2 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2076) EMP24_GP25L PF01105.24 CDJ47873.1 - 0.013 15.5 0.4 0.013 15.5 0.4 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ADP_ribosyl_GH PF03747.14 CDJ47873.1 - 0.046 13.4 4.0 0.13 11.9 4.0 1.7 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF1840 PF08895.11 CDJ47873.1 - 0.27 11.6 0.1 0.27 11.6 0.1 5.7 3 1 0 3 3 3 0 Domain of unknown function (DUF1840) FHIPEP PF00771.20 CDJ47873.1 - 7.9 4.8 12.8 12 4.2 0.4 2.4 2 0 0 2 2 2 0 FHIPEP family DUF4175 PF13779.6 CDJ47874.1 - 0.0032 15.5 18.7 0.0033 15.4 18.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) YfhO PF09586.10 CDJ47874.1 - 0.011 14.0 2.0 0.013 13.8 2.0 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO GRP PF07172.11 CDJ47874.1 - 0.017 15.8 5.9 1 10.1 1.4 2.3 2 0 0 2 2 2 0 Glycine rich protein family Exosortase_EpsH PF09721.10 CDJ47874.1 - 0.023 14.2 0.6 0.75 9.3 2.1 1.9 2 0 0 2 2 2 0 Transmembrane exosortase (Exosortase_EpsH) 7tm_7 PF08395.12 CDJ47874.1 - 0.074 12.2 5.4 0.089 12.0 5.4 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor Conotoxin PF02950.17 CDJ47874.1 - 0.086 13.9 4.1 5.1 8.2 0.2 2.8 3 0 0 3 3 3 0 Conotoxin XK-related PF09815.9 CDJ47874.1 - 0.2 10.7 3.3 0.26 10.3 3.3 1.1 1 0 0 1 1 1 0 XK-related protein DUF4064 PF13273.6 CDJ47874.1 - 0.22 11.8 4.9 7.1 7.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4131 PF13567.6 CDJ47874.1 - 0.27 10.8 7.2 1.3 8.6 7.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) CcmH PF03918.14 CDJ47874.1 - 0.62 9.3 7.2 1 8.7 0.2 2.2 1 1 1 2 2 2 0 Cytochrome C biogenesis protein EphA2_TM PF14575.6 CDJ47874.1 - 0.85 10.5 9.4 21 6.1 9.4 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TFIIA PF03153.13 CDJ47874.1 - 1.9 8.4 19.4 2.3 8.1 19.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CDJ47875.1 - 0.00033 19.8 8.7 0.00033 19.8 8.7 7.7 7 0 0 7 7 7 2 Transcriptional activator LAG-3 RskA PF10099.9 CDJ47875.1 - 0.00034 21.0 0.0 0.00034 21.0 0.0 16.0 5 4 4 10 10 10 2 Anti-sigma-K factor rskA Y_phosphatase3 PF13350.6 CDJ47875.1 - 0.28 11.1 2.8 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family VHS PF00790.19 CDJ47876.1 - 1.2e-05 25.1 0.1 0.17 11.7 0.0 2.4 2 0 0 2 2 2 2 VHS domain DUF4667 PF15700.5 CDJ47876.1 - 0.0064 16.6 0.7 0.0064 16.6 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) Velvet PF11754.8 CDJ47876.1 - 0.6 10.0 10.8 0.96 9.3 4.4 2.6 2 0 0 2 2 2 0 Velvet factor MID_MedPIWI PF18296.1 CDJ47876.1 - 0.61 9.8 15.1 5.8 6.6 0.9 3.2 3 0 0 3 3 3 0 MID domain of medPIWI DDHD PF02862.17 CDJ47876.1 - 0.99 9.5 6.3 3 8.0 4.2 2.2 2 0 0 2 2 2 0 DDHD domain Roughex PF06020.11 CDJ47876.1 - 1.4 8.0 10.6 2.8 7.0 10.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein RR_TM4-6 PF06459.12 CDJ47876.1 - 5.5 6.7 7.4 8.9 6.0 7.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spt20 PF12090.8 CDJ47877.1 - 0.0025 17.5 25.9 0.0025 17.5 25.9 3.9 2 1 1 3 3 3 1 Spt20 family FAM199X PF15814.5 CDJ47878.1 - 0.00075 18.7 12.8 0.00075 18.7 12.8 3.1 1 1 2 3 3 3 1 Protein family FAM199X DUF533 PF04391.12 CDJ47878.1 - 0.016 14.8 11.7 0.016 14.8 11.7 4.4 2 2 1 3 3 3 0 Protein of unknown function (DUF533) RAP1 PF07218.11 CDJ47878.1 - 0.5 8.6 12.4 0.55 8.5 12.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.13 CDJ47879.1 - 0.0022 16.2 35.6 0.0035 15.5 35.6 1.3 1 0 0 1 1 1 1 AF-4 proto-oncoprotein PrsW-protease PF13367.6 CDJ47881.1 - 1.8e-14 53.6 7.1 1.8e-14 53.6 7.1 3.1 3 0 0 3 3 3 1 PrsW family intramembrane metalloprotease SR-25 PF10500.9 CDJ47881.1 - 2.1e-05 24.2 11.5 2.1e-05 24.2 11.5 6.4 6 0 0 6 6 6 1 Nuclear RNA-splicing-associated protein Med3 PF11593.8 CDJ47881.1 - 0.0072 15.6 8.0 0.0072 15.6 8.0 7.0 5 2 3 8 8 8 1 Mediator complex subunit 3 fungal DUF4366 PF14283.6 CDJ47881.1 - 1.1 9.3 4.4 8.7 6.4 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) TFIIA PF03153.13 CDJ47881.1 - 1.6 8.7 71.0 0.12 12.3 40.2 3.2 3 1 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ47881.1 - 6.7 5.6 24.2 2.5 7.0 12.7 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Proteasome PF00227.26 CDJ47882.1 - 6.4e-50 169.3 0.1 8.1e-50 169.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ47882.1 - 8.6e-14 50.9 0.0 2e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Rotamase_2 PF13145.6 CDJ47882.1 - 0.03 15.2 0.1 0.053 14.3 0.1 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain Pkinase PF00069.25 CDJ47883.1 - 8.1e-40 136.9 8.8 1.4e-20 73.7 0.2 3.3 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ47883.1 - 1.2e-13 51.0 0.1 1.7e-09 37.3 0.3 3.0 4 0 0 4 4 4 2 Protein tyrosine kinase Spt5_N PF11942.8 CDJ47883.1 - 0.0064 17.5 5.5 0.0064 17.5 5.5 5.8 5 0 0 5 5 5 1 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.10 CDJ47883.1 - 4.4 7.8 10.3 14 6.2 10.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PseudoU_synth_1 PF01416.20 CDJ47885.1 - 1.6e-18 67.1 0.2 5.6e-17 62.2 0.1 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase Aha1_N PF09229.11 CDJ47885.1 - 0.079 13.2 0.2 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal Apt1 PF10351.9 CDJ47885.1 - 0.11 11.3 5.4 0.1 11.4 2.3 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ47885.1 - 6.7 5.1 17.4 0.82 8.2 10.9 2.1 2 0 0 2 2 2 0 Macoilin family Utp14 PF04615.13 CDJ47888.1 - 1.3 7.5 50.0 0.041 12.5 36.4 2.0 2 0 0 2 2 2 0 Utp14 protein DUF4471 PF14740.6 CDJ47888.1 - 6.5 5.9 23.9 2.9 7.0 16.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) DUF2828 PF11443.8 CDJ47888.1 - 8.8 4.3 26.6 5.4 5.0 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) tRNA_lig_CPD PF08302.11 CDJ47888.1 - 9.3 5.6 30.8 4.7 6.6 20.4 2.5 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain PEPCK_ATP PF01293.20 CDJ47889.1 - 4.6e-21 75.0 0.0 5.8e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Tic110 PF16940.5 CDJ47889.1 - 0.9 7.9 4.6 1.1 7.7 4.6 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Phage_lysis PF03245.13 CDJ47889.1 - 8.9 6.5 9.3 58 3.8 10.2 1.8 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein ExoD PF06055.12 CDJ47892.1 - 0.055 12.8 0.3 0.094 12.1 0.3 1.4 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD LMBR1 PF04791.16 CDJ47892.1 - 0.4 9.5 16.9 0.71 8.7 16.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2722 PF10846.8 CDJ47893.1 - 0.00064 18.8 0.9 0.00064 18.8 0.9 9.6 6 1 3 9 9 9 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ47893.1 - 0.0019 17.9 6.4 0.0019 17.9 6.4 8.5 6 1 2 8 8 8 3 Spt20 family FAST_1 PF06743.15 CDJ47893.1 - 1.1 9.2 14.3 2.6 8.1 0.0 4.8 5 0 0 5 5 5 0 FAST kinase-like protein, subdomain 1 AAA_23 PF13476.6 CDJ47894.1 - 0.52 10.8 20.6 2.9 8.3 2.2 3.1 3 0 0 3 3 3 0 AAA domain HC2 PF07382.11 CDJ47895.1 - 0.00068 19.8 0.3 0.00089 19.4 0.3 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 SID-1_RNA_chan PF13965.6 CDJ47895.1 - 0.42 9.0 2.2 0.38 9.1 2.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2935 PF11155.8 CDJ47896.1 - 0.012 15.9 0.2 0.099 13.0 0.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) SR-25 PF10500.9 CDJ47896.1 - 1.6 8.3 25.0 0.13 11.9 7.7 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ47897.1 - 0.014 15.7 3.7 0.014 15.7 3.7 3.1 2 1 0 2 2 2 0 Early growth response N-terminal domain DUF1645 PF07816.11 CDJ47897.1 - 0.055 14.0 0.2 0.055 14.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) RPA_C PF08784.11 CDJ47897.1 - 0.071 13.8 0.3 0.39 11.4 0.0 2.3 2 0 0 2 2 2 0 Replication protein A C terminal Sporozoite_P67 PF05642.11 CDJ47897.1 - 3.3 5.7 10.8 0.94 7.5 0.5 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen SR-25 PF10500.9 CDJ47897.1 - 5.4 6.6 25.1 1.3 8.6 2.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein YIF1 PF03878.15 CDJ47898.1 - 4e-31 108.4 0.0 1.8e-30 106.3 0.0 1.8 2 0 0 2 2 2 1 YIF1 SR-25 PF10500.9 CDJ47898.1 - 2.8 7.5 4.4 6.6 6.3 4.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ47899.1 - 0.13 12.5 9.8 0.14 12.4 9.8 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CamS PF07537.11 CDJ47900.1 - 4.6e-05 22.7 1.0 4.6e-05 22.7 1.0 1.9 2 0 0 2 2 2 1 CamS sex pheromone cAM373 precursor DUF2722 PF10846.8 CDJ47900.1 - 0.00091 18.3 6.7 0.00091 18.3 6.7 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ47900.1 - 0.0025 18.1 2.0 0.0025 18.1 2.0 3.9 3 1 1 4 4 3 2 Anti-sigma-K factor rskA EFG_II PF14492.6 CDJ47900.1 - 0.033 14.3 0.0 0.093 12.8 0.0 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II Abi_2 PF07751.11 CDJ47900.1 - 0.068 13.4 5.0 1.8 8.8 0.7 2.3 2 0 0 2 2 2 0 Abi-like protein Otopetrin PF03189.13 CDJ47900.1 - 0.92 8.2 9.9 1.5 7.6 9.9 1.2 1 0 0 1 1 1 0 Otopetrin Spore_coat_CotO PF14153.6 CDJ47900.1 - 1 9.3 27.2 0.32 10.9 4.1 3.2 3 0 0 3 3 3 0 Spore coat protein CotO Folate_carrier PF01770.18 CDJ47900.1 - 1.4 7.6 9.8 0.33 9.6 1.3 2.2 2 0 0 2 2 2 0 Reduced folate carrier DUF2370 PF10176.9 CDJ47900.1 - 4.5 6.9 9.6 2.8 7.5 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF979 PF06166.12 CDJ47900.1 - 7.5 5.6 5.4 0.49 9.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF979) CSG2 PF16965.5 CDJ47900.1 - 9.8 5.0 8.5 11 4.9 1.3 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator IMUP PF15761.5 CDJ47902.1 - 0.014 16.1 13.6 0.014 16.1 13.6 6.5 2 2 3 5 5 5 0 Immortalisation up-regulated protein Presenilin PF01080.17 CDJ47903.1 - 4.7 5.9 42.1 5.6 5.6 42.1 1.1 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ47904.1 - 0.019 14.6 37.5 0.037 13.6 20.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Shadoo PF14999.6 CDJ47904.1 - 0.023 14.8 6.5 0.023 14.8 6.5 2.2 2 1 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF755 PF05501.11 CDJ47904.1 - 0.18 12.1 43.1 0.083 13.2 22.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) TFIIA PF03153.13 CDJ47904.1 - 2.9 7.8 38.0 3.7 7.4 38.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VIR_N PF15912.5 CDJ47904.1 - 3 7.4 8.5 4 7.0 8.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF1645 PF07816.11 CDJ47904.1 - 4 8.0 23.4 0.77 10.3 11.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) eIF_4EBP PF05456.11 CDJ47905.1 - 0.018 14.9 2.4 0.018 14.9 2.4 5.2 5 1 0 5 5 5 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DnaJ PF00226.31 CDJ47906.1 - 7.2e-22 77.3 1.4 1.2e-21 76.6 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 CDJ47906.1 - 3.1e-08 33.8 0.0 5.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain Phage_sheath_1 PF04984.14 CDJ47906.1 - 0.012 15.5 0.2 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain Form-deh_trans PF09163.11 CDJ47906.1 - 3.2 7.6 8.1 6.7 6.6 8.1 1.6 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane SR-25 PF10500.9 CDJ47908.1 - 2e-05 24.3 18.0 2e-05 24.3 18.0 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Utp14 PF04615.13 CDJ47908.1 - 0.00091 17.9 10.0 0.0012 17.5 10.0 1.1 1 0 0 1 1 1 1 Utp14 protein ASFV_J13L PF05568.11 CDJ47908.1 - 0.0063 16.3 3.6 0.0063 16.3 3.6 1.9 2 0 0 2 2 2 1 African swine fever virus J13L protein CCSAP PF15748.5 CDJ47908.1 - 0.042 14.0 32.6 0.95 9.6 0.9 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated XAP5 PF04921.14 CDJ47908.1 - 0.26 11.1 11.4 0.32 10.8 7.7 2.0 2 0 0 2 2 2 0 XAP5, circadian clock regulator GRP PF07172.11 CDJ47908.1 - 1.4 9.7 4.6 11 6.7 0.1 2.7 2 0 0 2 2 2 0 Glycine rich protein family LAP1C PF05609.12 CDJ47908.1 - 1.8 7.5 29.3 0.016 14.4 19.4 1.9 1 1 1 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) DUF2207 PF09972.9 CDJ47908.1 - 3.3 6.4 8.0 33 3.1 7.9 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Conotoxin PF02950.17 CDJ47908.1 - 3.4 8.8 0.0 3.4 8.8 0.0 4.0 2 1 1 3 3 2 0 Conotoxin DUF2052 PF09747.9 CDJ47908.1 - 3.8 7.6 14.1 22 5.1 14.5 1.8 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Plasmodium_Vir PF05795.11 CDJ47908.1 - 4.9 6.5 14.0 11 5.3 14.0 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein MRP-S31 PF15433.6 CDJ47908.1 - 9 5.9 20.4 17 5.0 20.3 1.4 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF4778 PF16008.5 CDJ47909.1 - 0.0047 17.0 13.9 0.0055 16.8 13.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4778) SOG2 PF10428.9 CDJ47909.1 - 0.058 12.6 15.9 0.069 12.4 15.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein ALMT PF11744.8 CDJ47909.1 - 0.066 12.0 13.4 0.086 11.7 13.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter FA_desaturase PF00487.24 CDJ47909.1 - 0.076 12.8 0.0 0.097 12.5 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Lin-8 PF03353.15 CDJ47909.1 - 0.1 12.1 21.2 0.12 11.9 21.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LptF_LptG PF03739.14 CDJ47909.1 - 0.13 11.1 3.5 0.21 10.4 3.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG CDC45 PF02724.14 CDJ47909.1 - 0.16 10.2 17.5 0.2 9.9 17.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 CDJ47909.1 - 0.19 9.8 13.9 0.24 9.5 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.16 CDJ47909.1 - 0.22 11.5 13.3 0.32 11.0 13.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Draxin PF15550.6 CDJ47909.1 - 0.23 11.3 13.9 0.28 11.0 13.9 1.1 1 0 0 1 1 1 0 Draxin LAP1C PF05609.12 CDJ47909.1 - 0.24 10.5 22.6 0.27 10.3 22.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SWI-SNF_Ssr4 PF08549.10 CDJ47909.1 - 0.37 9.4 25.0 0.42 9.2 25.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PAT1 PF09770.9 CDJ47909.1 - 0.43 8.8 35.6 0.48 8.6 35.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dapper PF15268.6 CDJ47909.1 - 0.53 9.1 23.5 0.56 9.0 23.5 1.0 1 0 0 1 1 1 0 Dapper Pkinase_fungal PF17667.1 CDJ47909.1 - 0.59 8.9 7.8 0.66 8.7 7.8 1.1 1 0 0 1 1 1 0 Fungal protein kinase XRN_M PF17846.1 CDJ47909.1 - 1.4 7.8 15.8 1.9 7.3 15.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain SLC12 PF03522.15 CDJ47909.1 - 1.4 7.8 21.9 1.7 7.6 21.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF572 PF04502.13 CDJ47909.1 - 1.6 8.3 17.9 2 8.0 17.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CCSAP PF15748.5 CDJ47909.1 - 1.6 8.8 24.6 2 8.5 24.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF2052 PF09747.9 CDJ47909.1 - 1.8 8.7 22.6 2.5 8.2 22.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ47909.1 - 2.2 8.1 23.7 2.9 7.7 23.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 CDJ47909.1 - 2.8 8.1 19.2 3.8 7.7 19.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4569 PF15133.6 CDJ47909.1 - 3.6 7.2 21.3 4.8 6.8 21.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Med15 PF09606.10 CDJ47909.1 - 3.8 6.1 60.6 4 6.0 60.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Endostatin PF06482.11 CDJ47909.1 - 4 6.8 21.6 5.3 6.4 21.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Hid1 PF12722.7 CDJ47909.1 - 4.3 5.3 20.0 4.9 5.2 20.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 CDJ47909.1 - 5.3 4.0 22.2 6 3.8 22.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM60A PF15396.6 CDJ47909.1 - 8.4 6.3 17.1 13 5.8 17.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Pex14_N PF04695.13 CDJ47910.1 - 2.3e-05 25.1 48.2 0.0051 17.5 26.2 2.3 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF908 PF06012.12 CDJ47910.1 - 0.0006 19.3 6.5 0.0006 19.3 6.5 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) FAM199X PF15814.5 CDJ47910.1 - 0.005 15.9 20.6 0.005 15.9 20.6 2.7 2 1 0 2 2 1 1 Protein family FAM199X CCSAP PF15748.5 CDJ47910.1 - 0.0089 16.2 43.2 0.022 14.9 13.2 2.3 2 0 0 2 2 2 2 Centriole, cilia and spindle-associated Med15 PF09606.10 CDJ47910.1 - 0.014 14.2 68.5 0.013 14.2 39.0 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal NAM-associated PF14303.6 CDJ47910.1 - 0.014 16.1 11.2 0.014 16.1 11.2 2.4 2 0 0 2 2 1 0 No apical meristem-associated C-terminal domain Peptidase_S15 PF02129.18 CDJ47910.1 - 0.079 12.5 23.4 0.8 9.2 11.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) BAF1_ABF1 PF04684.13 CDJ47910.1 - 0.091 11.8 28.5 0.36 9.9 14.2 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor SOBP PF15279.6 CDJ47910.1 - 0.14 12.7 33.7 1 9.9 9.7 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein Velvet PF11754.8 CDJ47910.1 - 0.27 11.1 36.0 0.13 12.1 12.3 2.2 2 0 0 2 2 2 0 Velvet factor DUF572 PF04502.13 CDJ47910.1 - 0.35 10.5 32.7 0.51 9.9 8.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) GAGA_bind PF06217.12 CDJ47910.1 - 0.38 11.0 23.0 0.29 11.4 12.8 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family DUF5427 PF10310.9 CDJ47910.1 - 0.64 8.9 46.5 0.35 9.8 18.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5427) DUF4638 PF15472.6 CDJ47910.1 - 1.6 8.4 27.8 1.2 8.8 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) EPL1 PF10513.9 CDJ47910.1 - 1.6 9.1 33.7 0.42 11.0 4.7 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like SpoIIP PF07454.11 CDJ47910.1 - 1.9 7.9 32.6 0.059 12.8 2.6 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TCP PF03634.13 CDJ47910.1 - 1.9 9.0 38.4 0.74 10.4 12.9 2.5 2 0 0 2 2 2 0 TCP family transcription factor SMYLE_N PF18615.1 CDJ47910.1 - 2.1 7.8 28.7 0.64 9.5 8.1 2.1 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain eIF-3_zeta PF05091.12 CDJ47910.1 - 2.5 7.0 43.2 2.4 7.0 12.7 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MID_MedPIWI PF18296.1 CDJ47910.1 - 3.4 7.4 33.1 0.65 9.7 11.0 2.5 2 0 0 2 2 2 0 MID domain of medPIWI PIEZO PF15917.5 CDJ47910.1 - 3.6 7.0 38.1 3.9 6.9 21.7 2.2 2 0 0 2 2 2 0 Piezo RR_TM4-6 PF06459.12 CDJ47910.1 - 3.6 7.3 37.9 3.5 7.4 19.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Endostatin PF06482.11 CDJ47910.1 - 3.7 6.9 32.9 3.8 6.9 18.1 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Hid1 PF12722.7 CDJ47910.1 - 3.8 5.5 35.6 0.013 13.6 9.2 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein HAUS6_N PF14661.6 CDJ47910.1 - 4.1 6.9 32.9 2.9 7.4 19.5 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4746 PF15928.5 CDJ47910.1 - 5.4 6.3 20.0 0.35 10.2 6.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Rtf2 PF04641.12 CDJ47910.1 - 5.8 6.2 30.3 0.16 11.3 11.5 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger RskA PF10099.9 CDJ47910.1 - 7.3 6.9 41.9 1.9 8.8 8.5 3.4 1 1 2 3 3 3 0 Anti-sigma-K factor rskA VIT1 PF01988.19 CDJ47910.1 - 7.6 6.3 22.8 5.3 6.8 3.1 2.3 2 0 0 2 2 2 0 VIT family DUF913 PF06025.12 CDJ47910.1 - 7.8 5.4 24.9 0.046 12.7 6.5 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FGF-BP1 PF06473.12 CDJ47910.1 - 8.6 6.1 44.0 2.3 8.0 24.4 2.2 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) PPP4R2 PF09184.11 CDJ47910.1 - 9.1 5.8 18.8 3.4 7.2 3.6 2.1 2 0 0 2 2 2 0 PPP4R2 SID-1_RNA_chan PF13965.6 CDJ47911.1 - 0.37 9.1 13.9 0.43 8.9 13.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ47911.1 - 2.3 7.0 20.6 2.7 6.8 20.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF819 PF05684.12 CDJ47911.1 - 3.5 6.6 4.3 4.7 6.1 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF819) DUF3987 PF13148.6 CDJ47911.1 - 3.7 6.5 14.4 4.1 6.3 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF2126 PF09899.9 CDJ47911.1 - 4.5 5.2 19.7 5.3 5.0 19.7 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CSG2 PF16965.5 CDJ47911.1 - 4.7 6.1 19.7 5.3 5.9 19.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator TCP PF03634.13 CDJ47911.1 - 4.8 7.7 33.5 5.7 7.5 33.5 1.1 1 0 0 1 1 1 0 TCP family transcription factor SR-25 PF10500.9 CDJ47911.1 - 8.1 6.0 30.2 16 5.0 30.2 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TRAP_alpha PF03896.16 CDJ47911.1 - 8.4 5.5 17.6 1 8.5 13.5 1.5 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit MID_MedPIWI PF18296.1 CDJ47911.1 - 8.9 6.0 30.1 13 5.5 30.1 1.3 1 0 0 1 1 1 0 MID domain of medPIWI TetR_C_34 PF17929.1 CDJ47912.1 - 0.015 15.4 1.5 0.015 15.4 1.5 2.4 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain SRR1 PF07985.12 CDJ47912.1 - 0.018 15.0 1.1 0.028 14.5 1.1 1.3 1 0 0 1 1 1 0 SRR1 OmpH PF03938.14 CDJ47912.1 - 0.093 13.1 8.6 0.14 12.5 8.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_60s PF00428.19 CDJ47912.1 - 0.17 12.5 42.7 0.12 12.9 16.2 2.8 2 1 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ47912.1 - 0.63 10.0 9.5 0.75 9.7 9.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hemerythrin PF01814.23 CDJ47912.1 - 0.76 10.4 4.3 0.55 10.8 0.6 2.0 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Dehydrin PF00257.19 CDJ47912.1 - 1.1 9.8 9.2 1.5 9.4 0.3 2.1 2 0 0 2 2 2 0 Dehydrin LRR_4 PF12799.7 CDJ47913.1 - 2.9e-12 46.6 15.5 0.00016 22.0 0.8 4.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ47913.1 - 3.3e-09 36.4 17.2 0.00086 19.0 2.7 3.8 1 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 CDJ47913.1 - 8.4e-07 28.7 9.0 0.28 11.9 0.4 5.7 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 CDJ47913.1 - 2.9e-05 23.8 17.8 0.15 12.2 0.3 5.5 5 0 0 5 5 5 3 Leucine Rich repeat MukF_C PF17193.4 CDJ47913.1 - 0.0043 17.2 0.0 0.0064 16.6 0.0 1.3 1 0 0 1 1 1 1 MukF C-terminal domain SR-25 PF10500.9 CDJ47914.1 - 1.8 8.1 60.1 2 7.9 25.9 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ47916.1 - 0.00033 20.8 66.7 0.046 13.7 10.0 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit XRN_M PF17846.1 CDJ47916.1 - 0.00049 19.2 8.9 0.00052 19.1 5.3 2.0 2 0 0 2 2 2 1 Xrn1 helical domain DUF2052 PF09747.9 CDJ47916.1 - 0.0022 18.1 24.3 0.043 14.0 20.3 2.1 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Spt20 PF12090.8 CDJ47916.1 - 0.0047 16.6 10.0 0.0047 16.6 10.0 3.2 2 1 1 3 3 1 1 Spt20 family PA26 PF04636.13 CDJ47916.1 - 0.0056 15.7 11.5 0.0056 15.7 11.5 2.1 2 0 0 2 2 2 1 PA26 p53-induced protein (sestrin) LRR_6 PF13516.6 CDJ47916.1 - 0.0099 15.9 3.3 1.3 9.3 0.6 3.0 3 0 0 3 3 3 1 Leucine Rich repeat Afi1 PF07792.12 CDJ47916.1 - 0.0099 16.4 17.3 0.085 13.3 11.4 2.4 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Connexin PF00029.19 CDJ47916.1 - 0.01 15.6 13.7 0.7 9.6 11.9 2.3 2 0 0 2 2 2 0 Connexin LRR_4 PF12799.7 CDJ47916.1 - 0.012 16.0 3.8 1.6 9.2 2.2 2.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ47916.1 - 0.024 14.4 0.5 7.1 6.5 0.5 2.6 2 1 0 2 2 2 0 Leucine rich repeat CSG2 PF16965.5 CDJ47916.1 - 0.097 11.6 9.0 0.17 10.8 6.3 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator RR_TM4-6 PF06459.12 CDJ47916.1 - 0.1 12.4 28.5 0.22 11.3 22.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Serinc PF03348.15 CDJ47916.1 - 0.14 11.1 10.4 0.76 8.6 7.6 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) BORG_CEP PF14957.6 CDJ47916.1 - 0.15 13.3 23.8 1.6 9.9 1.4 2.2 2 0 0 2 2 2 0 Cdc42 effector V_ATPase_I PF01496.19 CDJ47916.1 - 0.17 9.7 27.5 0.15 10.0 20.8 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 CDJ47916.1 - 0.27 10.2 17.6 0.43 9.6 12.8 2.1 2 0 0 2 2 2 0 CLN3 protein DUF789 PF05623.12 CDJ47916.1 - 0.4 10.3 18.6 0.08 12.6 11.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF789) SpoIIP PF07454.11 CDJ47916.1 - 0.51 9.8 27.5 1.7 8.1 19.9 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2828 PF11443.8 CDJ47916.1 - 0.53 8.3 24.1 0.86 7.6 19.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ47916.1 - 0.56 8.9 34.7 0.49 9.1 24.8 2.1 2 0 0 2 2 2 0 Presenilin SID-1_RNA_chan PF13965.6 CDJ47916.1 - 0.58 8.5 8.7 0.32 9.4 5.7 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TRAP_alpha PF03896.16 CDJ47916.1 - 0.58 9.3 10.5 0.67 9.1 7.5 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CCDC53 PF10152.9 CDJ47916.1 - 0.6 10.5 29.7 0.36 11.2 19.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CobT PF06213.12 CDJ47916.1 - 0.65 9.3 42.8 1.7 8.0 30.4 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF4746 PF15928.5 CDJ47916.1 - 0.66 9.3 20.2 0.81 9.1 14.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) YABBY PF04690.13 CDJ47916.1 - 0.82 10.2 22.8 1.5 9.4 16.1 2.3 2 0 0 2 2 2 0 YABBY protein Tim54 PF11711.8 CDJ47916.1 - 0.93 8.2 23.1 1.7 7.4 17.7 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4638 PF15472.6 CDJ47916.1 - 1 9.0 23.4 0.75 9.5 17.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) NARP1 PF12569.8 CDJ47916.1 - 1.1 8.1 21.1 0.42 9.5 13.8 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RNA_pol_Rpc4 PF05132.14 CDJ47916.1 - 1.4 9.3 28.6 6.2 7.2 21.6 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Scs3p PF10261.9 CDJ47916.1 - 1.5 8.3 8.9 22 4.4 0.0 2.4 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM CBP_BcsG PF11658.8 CDJ47916.1 - 2.1 6.7 18.3 1.3 7.4 13.2 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG UPF0565 PF10561.9 CDJ47916.1 - 2.2 7.4 15.2 3.8 6.6 12.6 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Gti1_Pac2 PF09729.9 CDJ47916.1 - 2.7 8.1 28.3 1.7 8.7 18.0 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family Spore_coat_CotO PF14153.6 CDJ47916.1 - 2.7 7.9 39.9 2.8 7.9 1.9 2.1 2 0 0 2 2 2 0 Spore coat protein CotO ALMT PF11744.8 CDJ47916.1 - 2.8 6.7 22.7 0.61 8.9 15.3 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter Band_3_cyto PF07565.13 CDJ47916.1 - 3.2 7.5 27.3 3.7 7.3 1.0 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PTPRCAP PF15713.5 CDJ47916.1 - 3.2 8.0 29.7 4.4 7.6 20.5 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PNISR PF15996.5 CDJ47916.1 - 3.5 7.9 38.9 3 8.1 1.7 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Neur_chan_memb PF02932.16 CDJ47916.1 - 3.6 7.6 26.5 1.6 8.7 18.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BPL_N PF09825.9 CDJ47916.1 - 5.4 6.0 15.5 1.2 8.1 11.1 1.8 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal eIF-3_zeta PF05091.12 CDJ47916.1 - 6.6 5.6 41.6 4.1 6.3 30.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S15 PF02129.18 CDJ47916.1 - 7.1 6.1 19.7 15 5.1 13.8 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1180 PF06679.12 CDJ47916.1 - 8.4 6.8 13.5 6.2 7.2 6.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF1387 PF07139.11 CDJ47916.1 - 10 5.8 29.9 1.5 8.5 18.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) eIF-3_zeta PF05091.12 CDJ47917.1 - 6 5.7 20.2 7.9 5.3 20.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ47918.1 - 0.0013 18.9 34.1 0.0013 18.9 34.1 1.3 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ47918.1 - 0.091 11.3 6.2 0.13 10.8 6.2 1.2 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 CDJ47918.1 - 0.1 12.2 10.3 0.15 11.6 10.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SpoIIP PF07454.11 CDJ47918.1 - 0.13 11.7 6.3 0.19 11.1 6.3 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SPX PF03105.19 CDJ47918.1 - 0.2 11.5 12.4 0.28 11.1 12.4 1.3 1 0 0 1 1 1 0 SPX domain Connexin PF00029.19 CDJ47918.1 - 0.5 10.1 2.1 0.76 9.5 2.1 1.2 1 0 0 1 1 1 0 Connexin PAT1 PF09770.9 CDJ47918.1 - 3.9 5.6 20.6 5.4 5.2 20.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nucleo_P87 PF07267.11 CDJ47918.1 - 5 5.9 6.4 6.3 5.5 6.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RVT_1 PF00078.27 CDJ47919.1 - 2.3e-21 76.3 0.0 4.7e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ47919.1 - 2.3e-20 72.8 0.0 6.2e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ47919.1 - 3.4e-20 71.9 0.0 1.3e-19 70.1 0.0 2.1 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ47919.1 - 5.4e-13 49.2 0.0 1.9e-12 47.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 CDJ47919.1 - 5.7e-08 32.6 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ47919.1 - 0.00021 21.9 0.0 0.00044 20.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ47919.1 - 0.0016 18.9 0.0 0.0037 17.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Spt20 PF12090.8 CDJ47920.1 - 0.035 13.7 21.6 0.041 13.5 21.6 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ47920.1 - 0.23 11.4 21.3 0.22 11.5 21.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.3 CDJ47920.1 - 0.31 11.3 8.4 0.35 11.1 8.4 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain eIF-3_zeta PF05091.12 CDJ47920.1 - 1.2 8.1 14.0 1.3 7.9 14.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ47920.1 - 5.1 7.1 5.7 5.6 7.0 5.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ47920.1 - 6.3 5.5 10.5 6.6 5.4 10.5 1.0 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.8 CDJ47921.1 - 0.0073 16.1 3.0 0.008 15.9 3.0 1.3 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 Med15 PF09606.10 CDJ47921.1 - 0.011 14.5 25.5 0.012 14.4 25.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ47921.1 - 0.011 15.3 23.8 0.012 15.2 23.8 1.1 1 0 0 1 1 1 0 Spt20 family FHIPEP PF00771.20 CDJ47921.1 - 0.023 13.2 3.2 0.027 13.0 3.2 1.0 1 0 0 1 1 1 0 FHIPEP family FGAR-AT_N PF18076.1 CDJ47921.1 - 0.033 14.2 0.7 0.044 13.8 0.7 1.2 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal DUF2722 PF10846.8 CDJ47921.1 - 0.034 13.1 18.5 0.036 13.0 18.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ47921.1 - 0.053 13.5 10.6 0.059 13.4 10.6 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EIIBC-GUT_N PF03612.14 CDJ47921.1 - 0.077 12.7 6.1 0.1 12.3 6.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Gastrin PF00918.17 CDJ47921.1 - 0.11 13.5 6.1 0.12 13.3 6.1 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family TFIIA PF03153.13 CDJ47921.1 - 0.12 12.3 27.2 0.12 12.3 27.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ47921.1 - 0.13 11.2 7.8 0.12 11.3 7.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 CDJ47921.1 - 0.15 12.2 4.0 0.16 12.2 4.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TERB2 PF15101.6 CDJ47921.1 - 0.18 11.9 8.4 0.2 11.7 8.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 CDJ47921.1 - 0.2 10.4 5.0 0.18 10.5 5.0 1.1 1 0 0 1 1 1 0 Presenilin EIF4E-T PF10477.9 CDJ47921.1 - 0.46 9.2 13.8 0.51 9.1 13.8 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E FAM199X PF15814.5 CDJ47921.1 - 0.54 9.3 8.3 0.96 8.4 8.3 1.4 1 0 0 1 1 1 0 Protein family FAM199X DUF1980 PF09323.10 CDJ47921.1 - 0.74 9.7 3.1 0.8 9.6 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Neur_chan_memb PF02932.16 CDJ47921.1 - 0.77 9.8 3.6 0.71 9.9 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Orf78 PF06024.12 CDJ47921.1 - 0.82 10.0 3.3 1.1 9.6 3.3 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Activator_LAG-3 PF11498.8 CDJ47921.1 - 1.1 8.2 30.4 1.2 8.1 30.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4834 PF16118.5 CDJ47921.1 - 1.1 10.2 8.2 1.5 9.8 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PAT1 PF09770.9 CDJ47921.1 - 2 6.6 19.4 2.1 6.5 19.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 CDJ47921.1 - 3 8.5 25.8 5.4 7.6 25.8 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region THOC2_N PF16134.5 CDJ47921.1 - 3.3 6.2 8.2 4 5.9 8.2 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus UPF0560 PF10577.9 CDJ47921.1 - 4.7 5.6 14.5 5.1 5.5 14.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Roughex PF06020.11 CDJ47921.1 - 4.9 6.1 9.3 5.2 6.1 9.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein NUDE_C PF04880.13 CDJ47922.1 - 7.4 7.0 10.8 9 6.7 10.8 1.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region YABBY PF04690.13 CDJ47923.1 - 0.043 14.4 2.1 0.049 14.2 2.1 1.2 1 0 0 1 1 1 0 YABBY protein DUF533 PF04391.12 CDJ47923.1 - 0.089 12.4 10.0 0.11 12.1 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Spt20 PF12090.8 CDJ47923.1 - 0.097 12.3 28.9 0.1 12.2 28.9 1.1 1 0 0 1 1 1 0 Spt20 family eIF_4EBP PF05456.11 CDJ47923.1 - 0.1 12.6 6.2 0.12 12.4 6.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Pex14_N PF04695.13 CDJ47923.1 - 0.13 12.9 12.4 0.13 12.9 12.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 CDJ47923.1 - 0.33 12.0 9.4 0.38 11.8 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ47923.1 - 0.33 10.9 13.4 0.31 11.0 13.4 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EIIBC-GUT_N PF03612.14 CDJ47923.1 - 0.47 10.2 6.7 0.51 10.1 6.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Orf78 PF06024.12 CDJ47923.1 - 0.57 10.5 3.5 0.65 10.3 3.5 1.1 1 0 0 1 1 1 0 Orf78 (ac78) TORC_M PF12885.7 CDJ47923.1 - 1 9.2 6.5 1.1 9.2 6.5 1.1 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Band_3_cyto PF07565.13 CDJ47923.1 - 1.9 8.2 8.5 1.9 8.2 8.5 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3043 PF11241.8 CDJ47923.1 - 2.2 8.3 7.8 2.5 8.1 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) TFIIA PF03153.13 CDJ47923.1 - 2.3 8.1 26.2 2.2 8.2 26.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3464 PF11947.8 CDJ47923.1 - 4.8 6.9 8.7 5.1 6.8 8.7 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TMEM51 PF15345.6 CDJ47923.1 - 5.5 6.8 11.4 6.6 6.5 11.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 eIF-3_zeta PF05091.12 CDJ47923.1 - 5.5 5.9 16.0 5.7 5.8 16.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ47923.1 - 6.4 5.4 9.9 6 5.5 9.9 1.0 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CDJ47923.1 - 8.8 5.6 11.5 8.7 5.6 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PDGLE PF13190.6 CDJ47924.1 - 0.017 15.0 0.9 0.019 14.9 0.9 1.2 1 0 0 1 1 1 0 PDGLE domain Atg14 PF10186.9 CDJ47924.1 - 0.059 12.5 26.8 0.064 12.3 26.8 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spt20 PF12090.8 CDJ47924.1 - 0.82 9.2 38.2 0.95 9.0 38.2 1.1 1 0 0 1 1 1 0 Spt20 family DUF4200 PF13863.6 CDJ47924.1 - 0.83 10.1 33.0 0.94 9.9 33.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Ax_dynein_light PF10211.9 CDJ47924.1 - 2.7 7.9 29.3 3 7.8 29.3 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain FapA PF03961.13 CDJ47924.1 - 4.2 5.9 16.9 4.3 5.8 16.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A PIG-S PF10510.9 CDJ47924.1 - 4.3 6.0 14.1 4.5 6.0 14.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF4407 PF14362.6 CDJ47924.1 - 5.3 6.3 21.0 5.7 6.2 21.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4192 PF13830.6 CDJ47924.1 - 5.3 7.0 9.4 5.6 6.9 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) TFIIA PF03153.13 CDJ47924.1 - 5.5 6.9 32.9 5.7 6.8 32.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MctB PF11382.8 CDJ47924.1 - 5.9 6.5 15.4 6.6 6.3 15.4 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB DUF2722 PF10846.8 CDJ47924.1 - 6.3 5.6 28.6 7.2 5.4 28.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Asp-B-Hydro_N PF05279.11 CDJ47924.1 - 9.9 6.1 16.7 9.9 6.1 16.7 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Plasmodium_Vir PF05795.11 CDJ47925.1 - 0.0021 17.5 11.3 0.0024 17.4 11.3 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein DUF1645 PF07816.11 CDJ47925.1 - 0.017 15.7 15.4 0.025 15.1 15.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Med15 PF09606.10 CDJ47925.1 - 0.019 13.7 28.5 0.021 13.5 28.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2052 PF09747.9 CDJ47925.1 - 0.02 15.1 17.9 0.022 14.9 17.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Lin-8 PF03353.15 CDJ47925.1 - 0.044 13.3 17.5 0.053 13.1 17.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ47925.1 - 0.099 12.6 37.3 0.12 12.3 37.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CDJ47925.1 - 0.18 8.9 22.9 0.2 8.8 22.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDJ47925.1 - 0.27 9.7 18.2 0.31 9.6 18.2 1.1 1 0 0 1 1 1 0 Macoilin family IMUP PF15761.5 CDJ47925.1 - 0.34 11.6 14.4 0.13 12.9 8.8 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein Orf78 PF06024.12 CDJ47925.1 - 0.43 10.9 8.7 0.37 11.1 4.9 2.1 2 0 0 2 2 2 0 Orf78 (ac78) FHIPEP PF00771.20 CDJ47925.1 - 0.49 8.8 6.1 0.54 8.7 6.1 1.2 1 0 0 1 1 1 0 FHIPEP family Peptidase_S64 PF08192.11 CDJ47925.1 - 0.5 8.8 16.8 0.56 8.6 16.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 SLC12 PF03522.15 CDJ47925.1 - 0.53 9.3 15.2 0.63 9.0 15.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 O-antigen_lig PF13425.6 CDJ47925.1 - 1.2 7.9 2.7 1.3 7.7 2.7 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF1764 PF08576.10 CDJ47925.1 - 1.8 9.5 14.7 1.7 9.6 8.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) CNDH2_M PF16869.5 CDJ47925.1 - 2.1 9.0 21.6 0.92 10.2 5.5 2.1 2 0 0 2 2 2 0 PF16858 YfhO PF09586.10 CDJ47925.1 - 2.4 6.3 4.2 2.2 6.4 4.2 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4834 PF16118.5 CDJ47925.1 - 2.7 9.0 24.7 0.65 11.0 14.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Secretin_N_2 PF07655.13 CDJ47925.1 - 3.4 8.3 18.3 1.4 9.5 4.6 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain DUF3446 PF11928.8 CDJ47925.1 - 3.9 7.9 16.1 0.26 11.6 9.1 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain Borrelia_P83 PF05262.11 CDJ47925.1 - 4 5.8 16.3 4.4 5.7 16.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ALMT PF11744.8 CDJ47925.1 - 4.7 5.9 15.0 5.4 5.7 15.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SpoIIP PF07454.11 CDJ47925.1 - 6.1 6.2 20.2 9.5 5.6 20.1 1.5 1 1 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SRP-alpha_N PF04086.13 CDJ47925.1 - 6.2 6.7 22.0 6.8 6.5 22.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3807 PF12720.7 CDJ47925.1 - 6.2 7.1 27.2 2.5 8.3 17.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Sox_N PF12444.8 CDJ47925.1 - 6.2 8.0 17.6 5.5 8.2 3.4 2.3 2 0 0 2 2 2 0 Sox developmental protein N terminal Raftlin PF15250.6 CDJ47925.1 - 6.4 5.4 17.2 7.3 5.2 17.2 1.1 1 0 0 1 1 1 0 Raftlin TERB2 PF15101.6 CDJ47925.1 - 7.1 6.6 27.5 8.5 6.4 18.6 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 TFB6 PF17110.5 CDJ47925.1 - 7.6 6.3 12.0 0.72 9.6 7.5 1.5 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH AIF_C PF14721.6 CDJ47925.1 - 9.5 6.6 16.7 1.7 9.0 8.6 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Sin_N PF04801.13 CDJ47926.1 - 5.4e-55 187.3 7.6 5.4e-55 187.3 7.6 3.9 3 1 0 3 3 3 1 Sin-like protein conserved region DUF2142 PF09913.9 CDJ47926.1 - 0.003 16.5 2.5 0.003 16.5 2.5 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2142) SR-25 PF10500.9 CDJ47926.1 - 0.0087 15.7 12.5 0.0087 15.7 12.5 5.0 4 1 1 5 5 5 2 Nuclear RNA-splicing-associated protein Miga PF10265.9 CDJ47926.1 - 0.7 8.8 16.2 0.084 11.8 3.8 3.2 3 0 0 3 3 3 0 Mitoguardin Spt20 PF12090.8 CDJ47926.1 - 1.4 8.5 85.4 0.41 10.2 12.6 5.2 5 0 0 5 5 5 0 Spt20 family CIAPIN1 PF05093.13 CDJ47926.1 - 9 6.9 16.0 18 5.9 0.9 3.9 3 0 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis GrpE PF01025.19 CDJ47927.1 - 1.8e-39 135.1 11.3 3.3e-39 134.2 11.3 1.4 1 1 0 1 1 1 1 GrpE DUF2203 PF09969.9 CDJ47927.1 - 0.065 14.0 3.9 3.1 8.6 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4580 PF15162.6 CDJ47927.1 - 0.081 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) RmuC PF02646.16 CDJ47927.1 - 0.71 8.9 11.2 2.8 7.0 2.8 2.2 2 0 0 2 2 2 0 RmuC family DUF1664 PF07889.12 CDJ47927.1 - 1 9.4 8.1 0.41 10.7 3.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) RAP1 PF07218.11 CDJ47927.1 - 1.1 7.4 11.9 0.023 13.0 4.1 1.9 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) USP8_interact PF08941.10 CDJ47927.1 - 1.9 8.3 5.2 11 5.8 3.4 2.1 2 0 0 2 2 2 0 USP8 interacting HisKA PF00512.25 CDJ47927.1 - 3.4 7.8 5.3 3.6 7.7 0.5 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Activator_LAG-3 PF11498.8 CDJ47927.1 - 8.5 5.2 20.5 17 4.2 20.5 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Chromo PF00385.24 CDJ47928.1 - 0.00017 21.4 0.0 0.00036 20.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pectinesterase PF01095.19 CDJ47928.1 - 0.062 12.0 0.0 0.079 11.7 0.0 1.1 1 0 0 1 1 1 0 Pectinesterase zf-SNAP50_C PF12251.8 CDJ47929.1 - 1.2e-08 34.9 3.6 1.2e-08 34.9 3.6 3.5 3 1 0 3 3 3 1 snRNA-activating protein of 50kDa MW C terminal SUIM_assoc PF16619.5 CDJ47929.1 - 0.0015 18.5 0.0 0.0015 18.5 0.0 12.5 6 4 3 9 9 9 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ47929.1 - 0.0076 16.6 19.2 0.0076 16.6 19.2 6.6 2 2 4 6 6 6 1 Anti-sigma-K factor rskA MecA PF05389.12 CDJ47929.1 - 1.1 8.9 32.2 0.32 10.6 0.4 5.1 5 0 0 5 5 5 0 Negative regulator of genetic competence (MecA) CSG2 PF16965.5 CDJ47932.1 - 0.01 14.8 0.8 0.049 12.6 0.0 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator DUF4079 PF13301.6 CDJ47932.1 - 0.021 15.0 2.0 0.062 13.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) Cys_rich_CPXG PF14255.6 CDJ47932.1 - 0.032 14.1 0.9 11 6.0 0.2 2.9 2 0 0 2 2 2 0 Cysteine-rich CPXCG AIF_C PF14721.6 CDJ47932.1 - 0.055 13.8 0.5 0.055 13.8 0.5 4.0 4 1 0 4 4 4 0 Apoptosis-inducing factor, mitochondrion-associated, C-term WBP-1 PF11669.8 CDJ47933.1 - 0.41 11.3 3.4 0.65 10.6 3.4 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 Inj_translocase PF16928.5 CDJ47933.1 - 0.74 9.2 14.8 0.82 9.1 14.8 1.1 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome YnfE PF17452.2 CDJ47933.1 - 8.8 6.7 8.5 9.6 6.6 5.7 2.0 1 1 1 2 2 2 0 Uncharacterized YnfE-like Macoilin PF09726.9 CDJ47934.1 - 0.44 9.0 3.4 0.44 9.0 3.4 1.0 1 0 0 1 1 1 0 Macoilin family DUF3138 PF11336.8 CDJ47934.1 - 5.9 5.4 12.4 7.3 5.1 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) eIF2A PF08662.11 CDJ47935.1 - 7.4e-23 81.4 0.0 3.6e-16 59.6 0.0 3.6 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A GYF PF02213.16 CDJ47935.1 - 4.1e-15 55.2 0.1 8.8e-15 54.1 0.1 1.6 1 0 0 1 1 1 1 GYF domain SUIM_assoc PF16619.5 CDJ47935.1 - 0.0012 18.8 0.0 0.0012 18.8 0.0 27.3 14 7 3 17 17 17 2 Unstructured region C-term to UIM in Ataxin3 RNase_T PF00929.24 CDJ47936.1 - 3.2e-31 109.1 0.0 3.7e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CDJ47937.1 - 1.4e-37 129.1 0.1 2.5e-37 128.3 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 CDJ47937.1 - 2.7e-11 43.3 0.0 6.4e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 CDJ47937.1 - 0.0087 16.7 0.4 0.24 12.1 0.1 3.3 2 1 0 2 2 2 1 PMC2NT (NUC016) domain MecA PF05389.12 CDJ47937.1 - 0.93 9.1 6.9 0.37 10.4 0.1 3.0 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) DUF2894 PF11445.8 CDJ47939.1 - 0.02 15.4 1.3 0.04 14.4 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) Cation_efflux PF01545.21 CDJ47940.1 - 1.3e-36 126.2 6.6 2.6e-36 125.2 6.6 1.5 1 1 0 1 1 1 1 Cation efflux family HU-CCDC81_bac_2 PF18175.1 CDJ47941.1 - 0.0049 16.7 2.5 0.0063 16.4 0.9 1.9 1 1 1 2 2 2 1 CCDC81-like prokaryotic HU domain 2 TetR PF13972.6 CDJ47941.1 - 0.17 11.6 2.0 0.36 10.5 2.0 1.6 1 1 0 1 1 1 0 Bacterial transcriptional repressor Csm1_N PF18504.1 CDJ47941.1 - 0.41 11.0 6.7 2.7 8.4 0.3 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain Adhesin_P1_N PF18652.1 CDJ47941.1 - 4.3 7.4 6.3 1.3 9.1 1.6 2.1 1 1 1 2 2 2 0 Adhesin P1 N-terminal domain OmpH PF03938.14 CDJ47941.1 - 9.8 6.5 11.8 9.9 6.5 11.2 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA PF00004.29 CDJ47943.1 - 2.7e-16 60.2 0.0 5.7e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CDJ47943.1 - 1.5e-13 50.9 0.0 1.8e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 CDJ47943.1 - 2.1e-07 31.3 0.0 6e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rep_fac_C PF08542.11 CDJ47943.1 - 1.8e-06 28.2 0.0 5.6e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_16 PF13191.6 CDJ47943.1 - 2.7e-06 27.9 0.1 8.6e-05 23.0 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 CDJ47943.1 - 2e-05 24.5 0.1 4.6e-05 23.3 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CDJ47943.1 - 2.8e-05 24.3 0.0 6.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain Rad17 PF03215.15 CDJ47943.1 - 3.3e-05 23.9 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 CDJ47943.1 - 3.7e-05 23.5 0.0 8.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDJ47943.1 - 6.1e-05 23.1 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDJ47943.1 - 0.00018 21.5 0.0 0.00059 19.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CDJ47943.1 - 0.0018 18.6 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ47943.1 - 0.0032 17.2 0.0 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 CDJ47943.1 - 0.0042 16.4 0.0 0.0093 15.2 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 CDJ47943.1 - 0.0042 17.1 0.0 0.039 14.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ47943.1 - 0.01 15.6 0.0 0.2 11.4 0.0 2.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_7 PF12775.7 CDJ47943.1 - 0.014 14.9 0.0 0.034 13.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 CDJ47943.1 - 0.019 14.3 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CDJ47943.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CDJ47943.1 - 0.046 13.1 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 CDJ47943.1 - 0.062 12.5 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 CDJ47943.1 - 0.085 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.17 CDJ47944.1 - 1.3e-33 116.4 0.9 2.9e-13 49.7 0.0 4.5 3 2 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 CDJ47944.1 - 5.2e-31 108.0 0.0 5.6e-23 81.6 0.0 3.3 2 2 0 2 2 2 2 Protein kinase domain Ras PF00071.22 CDJ47945.1 - 6.3e-54 181.9 0.0 2.1e-53 180.3 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CDJ47945.1 - 9.2e-30 103.3 0.0 1.8e-29 102.4 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ47945.1 - 1.2e-09 37.8 0.2 1.7e-08 34.1 0.2 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDJ47945.1 - 0.00022 20.7 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ47945.1 - 0.0098 16.0 0.0 0.066 13.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ47945.1 - 0.022 14.7 0.0 4.4 7.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 CDJ47945.1 - 0.045 13.3 0.0 0.13 11.8 0.0 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Fer2_BFD PF04324.15 CDJ47945.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain AAA_16 PF13191.6 CDJ47945.1 - 0.14 12.6 0.0 0.2 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain MORN PF02493.20 CDJ47946.1 - 7.8e-53 173.3 52.5 8.1e-07 28.6 0.1 10.3 10 0 0 10 10 10 10 MORN repeat Tudor_2 PF18104.1 CDJ47946.1 - 0.011 15.4 1.2 38 4.1 0.0 5.2 6 0 0 6 6 6 0 Jumonji domain-containing protein 2A Tudor domain DUF3048_C PF17479.2 CDJ47946.1 - 0.55 10.6 7.8 12 6.3 0.4 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain Ferlin_C PF16165.5 CDJ47947.1 - 0.12 12.4 4.5 3.7 7.5 5.8 2.4 2 0 0 2 2 2 0 Ferlin C-terminus DUF3381 PF11861.8 CDJ47947.1 - 5.3 6.8 17.3 0.29 10.9 5.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF5337 PF17272.2 CDJ47948.1 - 0.057 13.2 1.6 6.6 6.6 1.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5337) DUF4179 PF13786.6 CDJ47948.1 - 2.9 8.4 4.4 18 5.9 0.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4179) TPR_7 PF13176.6 CDJ47949.1 - 0.038 14.0 0.3 0.33 11.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 CDJ47951.1 - 1.9e-14 53.2 0.0 3.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUIM_assoc PF16619.5 CDJ47954.1 - 9.5e-05 22.4 1.0 0.00019 21.5 1.0 1.5 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 ExoD PF06055.12 CDJ47955.1 - 0.064 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Pex14_N PF04695.13 CDJ47956.1 - 0.0037 17.9 18.0 0.0037 17.9 18.0 2.4 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CCSAP PF15748.5 CDJ47956.1 - 0.1 12.8 26.1 0.14 12.3 26.1 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RIFIN PF02009.16 CDJ47956.1 - 0.14 12.0 20.4 0.2 11.5 20.4 1.3 1 0 0 1 1 1 0 Rifin DUF572 PF04502.13 CDJ47956.1 - 0.23 11.1 19.4 0.28 10.8 19.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MRP-S27 PF10037.9 CDJ47956.1 - 0.28 10.0 23.5 0.34 9.7 23.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF31 PF01732.16 CDJ47956.1 - 0.58 9.6 10.5 0.69 9.4 10.5 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) MRP-S31 PF15433.6 CDJ47956.1 - 0.6 9.7 22.6 0.74 9.4 22.6 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 SLC12 PF03522.15 CDJ47956.1 - 0.81 8.6 25.3 1 8.3 25.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GAGA_bind PF06217.12 CDJ47956.1 - 0.84 9.9 17.1 1.1 9.5 17.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family ALMT PF11744.8 CDJ47956.1 - 1.5 7.5 18.8 2 7.1 18.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter GREB1 PF15782.5 CDJ47956.1 - 2.2 5.3 24.7 2.6 5.1 24.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Smg8_Smg9 PF10220.9 CDJ47956.1 - 2.3 6.4 23.7 2.7 6.2 23.7 1.0 1 0 0 1 1 1 0 Smg8_Smg9 SAPS PF04499.15 CDJ47956.1 - 2.5 6.8 18.2 3.1 6.5 18.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Exonuc_VII_L PF02601.15 CDJ47956.1 - 2.5 7.6 28.5 3.3 7.2 28.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CRT10 PF08728.10 CDJ47956.1 - 2.6 6.1 10.0 3 5.9 10.0 1.0 1 0 0 1 1 1 0 CRT10 DUF5523 PF17661.1 CDJ47956.1 - 2.7 7.6 26.3 3.6 7.2 3.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Hid1 PF12722.7 CDJ47956.1 - 3 5.9 25.7 3.5 5.6 25.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF45 PF01863.17 CDJ47956.1 - 3.1 7.8 15.9 4.4 7.3 15.9 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 Eapp_C PF10238.9 CDJ47956.1 - 3.5 7.7 26.4 3.2 7.8 12.6 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Peptidase_S49_N PF08496.10 CDJ47956.1 - 4.2 7.4 20.8 3.9 7.5 2.5 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1764 PF08576.10 CDJ47956.1 - 4.3 8.3 20.4 8.4 7.4 9.9 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) MDM10 PF12519.8 CDJ47956.1 - 4.6 6.0 19.6 6.1 5.6 19.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CTU2 PF10288.9 CDJ47956.1 - 5.1 7.4 21.4 5.1 7.4 3.8 2.5 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 PTPRCAP PF15713.5 CDJ47956.1 - 7.2 6.9 34.1 2.5 8.4 18.4 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated MPM1 PF17234.2 CDJ47956.1 - 9.5 6.4 27.9 11 6.2 14.1 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Phos_pyr_kin PF08543.12 CDJ47957.1 - 4.3e-08 32.8 0.0 4.3e-08 32.8 0.0 2.7 2 1 0 3 3 3 1 Phosphomethylpyrimidine kinase Spt20 PF12090.8 CDJ47957.1 - 6.1e-05 22.7 39.3 0.00067 19.3 10.4 2.2 2 0 0 2 2 2 2 Spt20 family Presenilin PF01080.17 CDJ47957.1 - 0.003 16.4 6.8 0.0044 15.8 6.8 1.2 1 0 0 1 1 1 1 Presenilin PfkB PF00294.24 CDJ47957.1 - 0.035 13.4 0.0 0.035 13.4 0.0 4.4 3 3 0 3 3 3 0 pfkB family carbohydrate kinase DUF4199 PF13858.6 CDJ47957.1 - 0.061 13.7 2.3 7.1 7.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) RLL PF10036.9 CDJ47957.1 - 0.095 12.5 20.7 0.35 10.7 2.7 2.3 1 1 1 2 2 2 0 RNA transcription, translation and transport factor protein MAP7 PF05672.11 CDJ47957.1 - 0.32 10.7 24.7 0.12 12.0 7.9 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family SLC12 PF03522.15 CDJ47957.1 - 1.3 7.9 9.0 2.3 7.1 9.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 FAM176 PF14851.6 CDJ47957.1 - 1.5 8.5 5.3 0.97 9.1 0.9 2.2 2 0 0 2 2 2 0 FAM176 family BCIP PF13862.6 CDJ47957.1 - 3.2 7.5 7.1 3.1 7.5 1.0 2.2 2 0 0 2 2 2 0 p21-C-terminal region-binding protein RPA43_OB PF17875.1 CDJ47957.1 - 3.4 8.3 11.6 8.3 7.1 3.0 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I RskA PF10099.9 CDJ47958.1 - 0.0029 17.9 0.0 0.0029 17.9 0.0 12.1 3 3 6 10 10 10 3 Anti-sigma-K factor rskA DUF4710 PF15828.5 CDJ47958.1 - 0.057 13.5 0.1 0.057 13.5 0.1 6.1 6 1 0 6 6 6 0 Domain of unknown function (DUF4710) RskA PF10099.9 CDJ47959.1 - 0.58 10.4 0.0 0.58 10.4 0.0 8.2 1 1 3 5 5 5 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ47960.1 - 0.1 12.2 52.9 0.078 12.6 1.4 4.4 4 0 0 4 4 4 0 Spt20 family RskA PF10099.9 CDJ47961.1 - 0.00058 20.2 15.4 0.00058 20.2 15.4 9.9 2 2 3 6 6 6 2 Anti-sigma-K factor rskA NAM-associated PF14303.6 CDJ47961.1 - 0.46 11.2 0.0 0.46 11.2 0.0 8.9 2 2 4 6 6 6 0 No apical meristem-associated C-terminal domain SR-25 PF10500.9 CDJ47962.1 - 0.015 14.9 19.1 0.015 14.9 19.1 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ47962.1 - 0.018 15.1 46.3 0.024 14.7 46.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pentapeptide_4 PF13599.6 CDJ47963.1 - 3.9e-05 23.7 0.0 0.00014 22.0 0.0 1.9 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Afi1 PF07792.12 CDJ47964.1 - 0.0053 17.2 1.3 0.0073 16.8 0.4 1.7 1 1 1 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking MMR1 PF08505.10 CDJ47964.1 - 0.0082 16.5 20.3 0.013 15.8 20.3 1.2 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein Apt1 PF10351.9 CDJ47964.1 - 0.026 13.4 18.0 0.037 12.9 18.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S64 PF08192.11 CDJ47964.1 - 0.15 10.5 21.9 0.24 9.9 21.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 SDA1 PF05285.12 CDJ47964.1 - 0.6 9.5 16.0 0.98 8.8 16.0 1.3 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 CDJ47964.1 - 0.88 8.1 17.2 1.2 7.6 17.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Paramyxo_ncap PF00973.19 CDJ47964.1 - 2.5 6.9 12.0 3.5 6.4 12.0 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CytochromB561_N PF09786.9 CDJ47964.1 - 3.9 6.4 18.7 5.2 5.9 18.7 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal PI3K_1B_p101 PF10486.9 CDJ47964.1 - 5.6 4.6 14.8 8.8 4.0 14.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4683 PF15735.5 CDJ47964.1 - 6 6.4 14.2 9.2 5.8 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) Spt20 PF12090.8 CDJ47965.1 - 0.0078 15.8 1.1 0.0078 15.8 1.1 6.3 6 1 0 6 6 6 3 Spt20 family CCSAP PF15748.5 CDJ47965.1 - 0.0096 16.1 7.7 0.0096 16.1 7.7 5.4 4 1 1 5 5 5 1 Centriole, cilia and spindle-associated DUF4131 PF13567.6 CDJ47965.1 - 0.032 13.9 0.5 0.032 13.9 0.5 4.5 5 1 0 5 5 5 0 Domain of unknown function (DUF4131) RskA PF10099.9 CDJ47965.1 - 0.21 11.8 0.1 0.21 11.8 0.1 9.8 3 3 2 6 6 6 0 Anti-sigma-K factor rskA DUF2207 PF09972.9 CDJ47965.1 - 0.27 10.0 0.2 0.68 8.6 0.2 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RNB PF00773.19 CDJ47966.1 - 1.9e-40 139.2 0.0 1.9e-40 139.2 0.0 7.2 4 3 0 5 5 5 1 RNB domain OB_Dis3 PF17849.1 CDJ47966.1 - 1.2e-09 38.0 0.0 6.5e-09 35.7 0.0 2.4 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CDJ47966.1 - 0.078 13.1 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 Cold shock domain MFS_1 PF07690.16 CDJ47967.1 - 0.0054 15.7 0.2 0.0089 15.0 0.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SWI-SNF_Ssr4 PF08549.10 CDJ47967.1 - 0.59 8.7 56.2 0.35 9.5 35.9 2.2 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) DUF572 PF04502.13 CDJ47967.1 - 5.6 6.5 52.8 1.2 8.7 32.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) TFIIF_alpha PF05793.12 CDJ47972.1 - 0.21 10.1 28.5 0.58 8.7 11.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ecl1 PF12855.7 CDJ47972.1 - 0.66 11.1 27.5 0.19 12.9 5.3 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins NEMP PF10225.9 CDJ47972.1 - 1.6 8.4 6.9 2.7 7.6 6.9 1.3 1 0 0 1 1 1 0 NEMP family Band_3_cyto PF07565.13 CDJ47972.1 - 2.3 7.9 14.8 4 7.1 14.8 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Connexin PF00029.19 CDJ47972.1 - 3.7 7.2 9.4 3.6 7.3 8.3 1.7 2 0 0 2 2 2 0 Connexin PBP1_TM PF14812.6 CDJ47972.1 - 4.8 7.6 15.4 5.1 7.5 5.9 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YfhO PF09586.10 CDJ47972.1 - 7.3 4.7 7.8 17 3.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Na_trans_assoc PF06512.13 CDJ47972.1 - 8.1 6.7 19.1 2.5 8.3 9.0 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated SID-1_RNA_chan PF13965.6 CDJ47972.1 - 9.3 4.5 10.0 8.1 4.7 7.9 1.7 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Hamartin PF04388.12 CDJ47975.1 - 0.0044 15.8 37.9 0.006 15.3 37.9 1.2 1 0 0 1 1 1 1 Hamartin protein CDC45 PF02724.14 CDJ47975.1 - 5 5.3 24.4 7.1 4.8 24.4 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 CDJ47975.1 - 6.2 6.3 17.0 11 5.5 17.0 1.4 1 0 0 1 1 1 0 PPP4R2 SMYLE_N PF18615.1 CDJ47975.1 - 9.2 5.7 24.7 13 5.2 24.7 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SUIM_assoc PF16619.5 CDJ47976.1 - 0.15 12.2 0.1 0.086 12.9 3.9 12.5 9 4 1 10 10 10 0 Unstructured region C-term to UIM in Ataxin3 RPA43_OB PF17875.1 CDJ47977.1 - 0.012 16.3 1.0 0.012 16.3 1.0 2.1 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I MPM1 PF17234.2 CDJ47977.1 - 0.024 14.9 15.6 0.054 13.7 7.4 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 RskA PF10099.9 CDJ47977.1 - 0.047 14.0 24.7 0.082 13.2 0.2 2.5 1 1 0 2 2 2 0 Anti-sigma-K factor rskA Claudin_2 PF13903.6 CDJ47977.1 - 0.048 13.4 3.1 0.067 12.9 0.1 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PA26 PF04636.13 CDJ47977.1 - 0.06 12.3 4.9 0.87 8.4 2.8 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Cwf_Cwc_15 PF04889.12 CDJ47977.1 - 0.079 12.7 12.3 0.075 12.8 2.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Spt20 PF12090.8 CDJ47977.1 - 0.36 10.4 40.2 0.018 14.6 16.0 2.2 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ47977.1 - 0.76 9.7 46.1 0.49 10.3 20.4 2.0 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nha1_C PF08619.10 CDJ47977.1 - 1.3 8.2 20.1 0.32 10.2 10.5 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus CPSF100_C PF13299.6 CDJ47977.1 - 1.4 9.0 6.9 0.9 9.7 0.8 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PAP1 PF08601.10 CDJ47977.1 - 2.7 7.7 29.6 0.87 9.3 12.5 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 Peptidase_S49_N PF08496.10 CDJ47977.1 - 3 7.9 8.3 7 6.7 1.8 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Afi1 PF07792.12 CDJ47977.1 - 3.2 8.2 9.6 0.83 10.1 2.5 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Sporozoite_P67 PF05642.11 CDJ47977.1 - 3.3 5.7 14.0 0.055 11.6 3.9 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF4407 PF14362.6 CDJ47977.1 - 3.5 6.9 18.7 0.23 10.8 6.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Miga PF10265.9 CDJ47977.1 - 5.5 5.9 25.6 9.5 5.1 25.6 1.4 1 1 0 1 1 1 0 Mitoguardin GREB1 PF15782.5 CDJ47977.1 - 5.9 3.9 28.3 0.47 7.5 7.8 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer DUF4834 PF16118.5 CDJ47977.1 - 6.1 7.9 20.8 0.67 11.0 6.0 3.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4834) IHABP4_N PF16174.5 CDJ47977.1 - 8.9 6.9 17.9 0.51 10.9 7.5 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal BAF1_ABF1 PF04684.13 CDJ47979.1 - 0.45 9.5 20.1 0.2 10.7 3.0 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Apt1 PF10351.9 CDJ47979.1 - 2.7 6.7 32.2 0.78 8.5 12.1 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain PAP1 PF08601.10 CDJ47979.1 - 3.7 7.2 37.3 0.085 12.6 11.3 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 DUF2052 PF09747.9 CDJ47979.1 - 4.6 7.3 14.5 9.3 6.3 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FCP1_C PF09309.10 CDJ47979.1 - 7.9 6.3 29.5 3.7 7.3 10.4 2.1 2 0 0 2 2 2 0 FCP1, C-terminal Miga PF10265.9 CDJ47979.1 - 8.4 5.2 31.9 0.62 9.0 11.4 2.0 2 0 0 2 2 2 0 Mitoguardin RRM_1 PF00076.22 CDJ47980.1 - 8.3e-26 89.6 0.1 4.7e-17 61.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ47980.1 - 9.2e-06 25.7 0.2 0.046 13.8 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CDJ47980.1 - 1.4e-05 24.6 0.1 0.0033 17.0 0.0 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDJ47980.1 - 0.06 13.4 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 PHM7_cyt PF14703.6 CDJ47980.1 - 0.26 11.5 0.0 0.37 11.0 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter NAD_binding_8 PF13450.6 CDJ47981.1 - 2.2e-06 27.8 6.1 2.2e-06 27.8 6.1 4.6 3 2 1 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ47981.1 - 2.3e-06 27.1 2.3 5.9e-06 25.7 2.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ47981.1 - 4.5e-05 23.0 7.4 4.5e-05 23.0 7.4 5.2 6 1 0 6 6 6 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CDJ47981.1 - 5.3e-05 22.1 1.8 9.8e-05 21.2 1.8 1.4 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 CDJ47981.1 - 9.5e-05 21.8 3.2 0.00022 20.7 3.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 CDJ47981.1 - 0.00036 21.0 2.8 0.00074 20.0 2.8 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ47981.1 - 0.0074 15.6 1.3 0.013 14.7 1.3 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 CDJ47981.1 - 0.32 10.2 0.9 0.57 9.4 0.9 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Kinesin PF00225.23 CDJ47982.1 - 2.5e-94 315.9 0.0 2.5e-94 315.9 0.0 2.1 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ47982.1 - 2e-20 73.3 0.2 9.1e-20 71.1 0.2 2.2 1 1 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 CDJ47982.1 - 1.1e-05 25.8 0.1 0.0014 19.0 0.0 3.2 2 0 0 2 2 2 1 Kinesin protein 1B Kinesin_assoc PF16183.5 CDJ47982.1 - 0.0011 19.1 0.8 0.0011 19.1 0.8 3.8 2 1 1 3 3 3 2 Kinesin-associated FHA PF00498.26 CDJ47982.1 - 0.0021 18.4 0.1 0.0069 16.7 0.0 1.9 2 0 0 2 2 2 1 FHA domain DUF2015 PF09435.10 CDJ47982.1 - 0.24 11.3 1.0 0.55 10.1 1.0 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) PAP_central PF04928.17 CDJ47982.1 - 2.9 6.8 4.4 0.91 8.4 0.7 2.0 2 0 0 2 2 2 0 Poly(A) polymerase central domain Ion_trans PF00520.31 CDJ47983.1 - 3.7e-38 131.1 59.6 5.2e-17 61.9 13.4 4.8 4 1 1 5 5 5 4 Ion transport protein ANAPC4_WD40 PF12894.7 CDJ47984.1 - 0.00045 20.5 0.0 0.089 13.1 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ47985.1 - 0.00061 20.5 8.9 2.3 9.2 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ47985.1 - 0.034 14.4 0.0 10 6.5 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 CDJ47986.1 - 0.0003 21.2 1.3 0.002 18.5 0.2 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ47986.1 - 0.0047 16.8 0.3 0.027 14.4 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CDJ47986.1 - 0.018 14.9 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 CDJ47986.1 - 0.2 11.3 1.2 4.9 6.9 0.0 3.2 3 0 0 3 3 3 0 EF hand Filament PF00038.21 CDJ47987.1 - 0.00078 19.1 11.7 0.0014 18.3 11.7 1.3 1 0 0 1 1 1 1 Intermediate filament protein DegQ PF08181.11 CDJ47987.1 - 0.0051 16.9 0.1 0.0051 16.9 0.1 2.4 2 0 0 2 2 2 1 DegQ (SacQ) family IFT57 PF10498.9 CDJ47987.1 - 0.0053 15.8 15.6 0.37 9.7 6.6 3.4 2 2 1 3 3 3 2 Intra-flagellar transport protein 57 Cep57_MT_bd PF06657.13 CDJ47987.1 - 0.034 14.6 11.0 0.051 14.0 0.2 3.9 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TFIIA PF03153.13 CDJ47987.1 - 1.1 9.2 18.8 1.9 8.4 18.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LepB_N PF18640.1 CDJ47987.1 - 2.9 7.5 6.1 11 5.5 6.1 2.0 1 1 0 1 1 1 0 LepB N-terminal domain Pex14_N PF04695.13 CDJ47988.1 - 0.017 15.8 9.7 0.017 15.8 9.7 4.1 3 1 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s PF00428.19 CDJ47988.1 - 0.019 15.6 2.1 0.019 15.6 2.1 5.3 6 1 0 6 6 6 0 60s Acidic ribosomal protein VIT1 PF01988.19 CDJ47988.1 - 0.14 12.0 0.1 0.14 12.0 0.1 4.8 3 1 3 6 6 6 0 VIT family ThrE PF06738.12 CDJ47988.1 - 1.5 8.2 5.9 0.19 11.1 0.5 2.3 3 0 0 3 3 3 0 Putative threonine/serine exporter K_channel_TID PF07941.11 CDJ47989.1 - 0.073 13.5 10.9 0.079 13.4 1.7 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Spt20 PF12090.8 CDJ47989.1 - 0.2 11.2 1.8 0.29 10.7 1.8 1.2 1 0 0 1 1 1 0 Spt20 family Sec63 PF02889.16 CDJ47990.1 - 9.6e-70 234.7 0.5 9.4e-35 120.0 2.1 4.8 3 2 0 3 3 3 3 Sec63 Brl domain DEAD PF00270.29 CDJ47990.1 - 2.1e-27 96.0 0.0 4.2e-20 72.2 0.0 3.5 4 0 0 4 4 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ47990.1 - 1.4e-05 25.3 1.3 0.016 15.5 0.0 3.9 2 2 0 2 2 2 1 AAA domain TFIIA PF03153.13 CDJ47990.1 - 0.00035 20.7 95.0 0.017 15.2 40.6 4.5 5 0 0 5 5 5 3 Transcription factor IIA, alpha/beta subunit Helicase_C PF00271.31 CDJ47990.1 - 0.00092 19.5 0.0 0.00092 19.5 0.0 4.2 4 1 0 4 4 2 1 Helicase conserved C-terminal domain FAM76 PF16046.5 CDJ47990.1 - 0.0013 18.1 10.9 0.0013 18.1 10.9 3.6 4 0 0 4 4 4 2 FAM76 protein HNOBA PF07701.14 CDJ47990.1 - 0.0039 16.7 12.9 0.32 10.4 4.2 3.8 3 0 0 3 3 3 2 Heme NO binding associated eIF-3_zeta PF05091.12 CDJ47990.1 - 0.011 14.7 50.6 0.36 9.8 22.4 4.1 4 0 0 4 4 4 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 CDJ47990.1 - 5.3 6.4 37.5 0.11 12.0 13.3 3.4 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) Isy1 PF06246.12 CDJ47990.1 - 6.6 6.2 38.0 2.5 7.6 6.0 3.7 4 0 0 4 4 4 0 Isy1-like splicing family Endostatin PF06482.11 CDJ47990.1 - 7.8 5.9 33.4 0.73 9.2 14.5 3.6 3 0 0 3 3 3 0 Collagenase NC10 and Endostatin SAPS PF04499.15 CDJ47990.1 - 8.7 5.0 21.9 10 4.8 1.3 2.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF2722 PF10846.8 CDJ47991.1 - 4.5e-05 22.6 2.7 9.2e-05 21.6 2.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ47991.1 - 0.00047 19.8 11.0 0.00066 19.4 11.0 1.2 1 0 0 1 1 1 1 Spt20 family Activator_LAG-3 PF11498.8 CDJ47991.1 - 0.1 11.6 19.7 0.16 10.9 19.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ORC_WH_C PF18137.1 CDJ47991.1 - 0.11 12.5 4.5 0.34 11.0 4.5 1.8 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Suf PF05843.14 CDJ47991.1 - 0.21 11.6 6.5 0.43 10.5 6.5 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Roughex PF06020.11 CDJ47991.1 - 0.95 8.5 3.5 1.5 7.8 3.5 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF4834 PF16118.5 CDJ47991.1 - 5 8.1 5.9 10 7.2 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4569 PF15133.6 CDJ47992.1 - 1.4 8.6 29.6 1.7 8.3 29.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Presenilin PF01080.17 CDJ47992.1 - 3.4 6.3 33.7 3.8 6.2 33.7 1.1 1 0 0 1 1 1 0 Presenilin DUF2151 PF10221.9 CDJ47992.1 - 5.2 5.5 21.7 6.2 5.3 21.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4045 PF13254.6 CDJ47992.1 - 6 6.4 25.2 7.3 6.1 25.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SLC12 PF03522.15 CDJ47992.1 - 7.2 5.5 34.6 8.9 5.2 34.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Sec62 PF03839.16 CDJ47992.1 - 8.7 5.8 24.9 11 5.4 24.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 GDA1_CD39 PF01150.17 CDJ47993.1 - 2.3e-16 59.5 10.4 2.6e-08 33.0 10.8 2.3 2 1 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Caldesmon PF02029.15 CDJ47993.1 - 4.7e-06 25.6 24.2 6.7e-06 25.1 24.2 1.2 1 0 0 1 1 1 1 Caldesmon CDC45 PF02724.14 CDJ47993.1 - 0.0011 17.4 21.7 0.0016 16.8 21.7 1.1 1 0 0 1 1 1 1 CDC45-like protein LAP1C PF05609.12 CDJ47993.1 - 0.099 11.7 26.3 0.16 11.0 26.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2721 PF11026.8 CDJ47993.1 - 1.5 8.7 0.0 1.5 8.7 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) CCSAP PF15748.5 CDJ47993.1 - 2.1 8.5 39.6 21 5.2 35.1 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Cwf_Cwc_15 PF04889.12 CDJ47993.1 - 4.4 7.0 38.4 7 6.3 38.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RskA PF10099.9 CDJ47994.1 - 0.019 15.3 8.4 0.024 15.0 8.4 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3357 PF11837.8 CDJ47994.1 - 0.048 14.1 0.5 0.056 13.9 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) CD20 PF04103.15 CDJ47994.1 - 0.21 11.7 0.1 0.23 11.6 0.1 1.1 1 0 0 1 1 1 0 CD20-like family PMSI1 PF15322.6 CDJ47994.1 - 0.38 10.2 9.7 0.41 10.0 9.7 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Otopetrin PF03189.13 CDJ47994.1 - 0.74 8.6 5.7 0.69 8.7 5.7 1.1 1 0 0 1 1 1 0 Otopetrin Connexin PF00029.19 CDJ47994.1 - 0.91 9.2 9.4 0.93 9.2 9.4 1.1 1 0 0 1 1 1 0 Connexin CDRT4 PF15213.6 CDJ47994.1 - 0.91 10.1 5.6 1 10.0 5.6 1.1 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Nucleoside_tran PF01733.18 CDJ47994.1 - 0.97 8.7 3.5 1.1 8.6 3.5 1.0 1 0 0 1 1 1 0 Nucleoside transporter AXIN1_TNKS_BD PF16646.5 CDJ47994.1 - 2.2 9.3 7.2 2.1 9.3 6.6 1.3 1 1 0 1 1 1 0 Axin-1 tankyrase binding domain V_ATPase_I PF01496.19 CDJ47994.1 - 4 5.2 14.4 4 5.2 14.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 CDJ47994.1 - 4.1 7.2 18.9 4.2 7.2 18.4 1.3 1 1 0 1 1 1 0 Septum formation initiator SID-1_RNA_chan PF13965.6 CDJ47994.1 - 5 5.4 5.4 4.7 5.5 5.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 OATP PF03137.20 CDJ47994.1 - 5.6 5.1 5.2 5.5 5.2 5.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family NEMP PF10225.9 CDJ47994.1 - 6.4 6.4 7.3 6.4 6.4 7.3 1.0 1 0 0 1 1 1 0 NEMP family CLN3 PF02487.17 CDJ47994.1 - 8.2 5.4 9.8 8 5.4 9.8 1.0 1 0 0 1 1 1 0 CLN3 protein Helicase_C PF00271.31 CDJ47995.1 - 2.1e-08 34.5 0.3 2.1e-08 34.5 0.3 3.9 2 2 1 3 3 3 1 Helicase conserved C-terminal domain Adeno_E1B_55K_N PF04623.12 CDJ47995.1 - 0.016 15.9 5.3 0.065 13.9 5.3 2.0 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus Sporozoite_P67 PF05642.11 CDJ47997.1 - 0.023 12.8 21.7 0.053 11.6 21.7 1.6 1 1 0 1 1 1 0 Sporozoite P67 surface antigen PAT1 PF09770.9 CDJ47997.1 - 3.3 5.9 15.2 4.5 5.4 15.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WBP-1 PF11669.8 CDJ47997.1 - 3.8 8.2 5.8 8.7 7.0 5.8 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 NST1 PF13945.6 CDJ47997.1 - 4.7 7.3 19.6 0.26 11.4 14.0 1.7 2 0 0 2 2 2 0 Salt tolerance down-regulator SLC12 PF03522.15 CDJ47997.1 - 5.5 5.9 8.7 8.6 5.3 8.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Plasmodium_Vir PF05795.11 CDJ47997.1 - 6.4 6.1 14.4 0.17 11.3 7.9 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein TFIIA PF03153.13 CDJ47997.1 - 7.1 6.5 26.6 8.6 6.2 25.6 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ47999.1 - 0.0064 16.8 5.6 0.0072 16.6 5.6 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF3824 PF12868.7 CDJ47999.1 - 0.018 15.7 12.3 0.019 15.6 12.3 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Menin PF05053.13 CDJ47999.1 - 0.48 8.7 9.4 0.47 8.8 9.4 1.0 1 0 0 1 1 1 0 Menin DUF4820 PF16091.5 CDJ47999.1 - 0.53 9.6 9.2 0.56 9.5 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) HA2 PF04408.23 CDJ47999.1 - 0.54 10.6 5.6 0.62 10.4 5.6 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) DUF4834 PF16118.5 CDJ47999.1 - 0.93 10.5 10.3 1.1 10.3 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 CDJ47999.1 - 1.1 8.0 17.8 1.2 7.9 17.8 1.2 1 0 0 1 1 1 0 Androgen receptor FAM176 PF14851.6 CDJ47999.1 - 1.2 8.8 5.9 1.2 8.7 5.9 1.1 1 0 0 1 1 1 0 FAM176 family HNOBA PF07701.14 CDJ47999.1 - 1.2 8.5 8.9 1.3 8.4 8.9 1.0 1 0 0 1 1 1 0 Heme NO binding associated FHIPEP PF00771.20 CDJ47999.1 - 2.5 6.5 5.8 2.4 6.5 5.8 1.0 1 0 0 1 1 1 0 FHIPEP family AIF_C PF14721.6 CDJ47999.1 - 2.8 8.3 7.3 2.8 8.3 7.3 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term R_equi_Vir PF05526.11 CDJ47999.1 - 3.4 7.5 5.1 3.7 7.4 5.1 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein TMEM51 PF15345.6 CDJ47999.1 - 4.5 7.1 11.5 5 6.9 11.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 RPN2_C PF18004.1 CDJ47999.1 - 8.9 6.2 14.7 9 6.2 14.7 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Spt20 PF12090.8 CDJ47999.1 - 9.3 5.8 16.7 9.3 5.8 16.7 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ48000.1 - 0.0016 17.5 15.4 0.0016 17.5 15.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Ribosomal_60s PF00428.19 CDJ48000.1 - 0.0023 18.5 11.9 0.0023 18.5 11.9 8.4 7 1 1 8 8 7 1 60s Acidic ribosomal protein Trp_oprn_chp PF09534.10 CDJ48000.1 - 0.0039 17.0 1.4 0.0039 17.0 1.4 4.5 4 1 0 4 4 3 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Presenilin PF01080.17 CDJ48000.1 - 0.0046 15.8 12.9 0.0084 14.9 12.9 1.4 1 0 0 1 1 1 1 Presenilin DUF3537 PF12056.8 CDJ48000.1 - 0.042 12.7 4.8 0.093 11.5 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) FAM91_C PF14648.6 CDJ48000.1 - 0.099 11.5 7.3 0.14 11.0 7.3 1.3 1 0 0 1 1 1 0 FAM91 C-terminus SpoIIP PF07454.11 CDJ48000.1 - 0.35 10.3 12.1 0.01 15.3 4.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 CDJ48000.1 - 0.42 10.7 12.5 0.07 13.2 5.7 2.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein SID-1_RNA_chan PF13965.6 CDJ48000.1 - 0.69 8.3 4.0 1.2 7.4 4.0 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ48000.1 - 2.7 6.8 6.9 4.9 6.0 6.9 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Jak1_Phl PF17887.1 CDJ48000.1 - 6.1 6.8 14.0 0.23 11.4 6.9 2.1 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain DUF4746 PF15928.5 CDJ48000.1 - 8.7 5.7 16.2 0.69 9.3 8.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) G0-G1_switch_2 PF15103.6 CDJ48000.1 - 10 6.6 15.4 0.37 11.2 3.3 3.2 3 0 0 3 3 3 0 G0/G1 switch protein 2 EzrA PF06160.12 CDJ48001.1 - 0.0012 17.1 9.6 0.0012 17.1 9.6 2.6 2 2 0 2 2 2 1 Septation ring formation regulator, EzrA GAS PF13851.6 CDJ48001.1 - 0.0021 17.5 8.2 0.0021 17.5 8.2 4.4 2 2 1 4 4 4 1 Growth-arrest specific micro-tubule binding Holin_BhlA PF10960.8 CDJ48001.1 - 0.19 11.7 7.3 0.91 9.5 0.1 3.7 2 1 0 2 2 2 0 BhlA holin family DUF4795 PF16043.5 CDJ48001.1 - 0.25 10.9 26.4 0.62 9.6 11.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) NuiA PF07924.11 CDJ48001.1 - 0.49 10.8 2.7 1.5 9.2 0.2 2.7 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein DUF1664 PF07889.12 CDJ48001.1 - 0.8 9.8 21.6 0.62 10.1 5.6 4.4 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) TetR PF13972.6 CDJ48001.1 - 0.97 9.1 8.6 0.076 12.7 0.7 2.7 2 1 1 3 3 3 0 Bacterial transcriptional repressor BLOC1_2 PF10046.9 CDJ48001.1 - 1.3 9.3 23.2 1.4 9.3 0.7 5.2 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 CDJ48001.1 - 3.4 7.7 14.3 7.6 6.6 7.0 3.6 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 CDJ48001.1 - 7.2 5.4 35.1 0.13 11.1 13.9 3.7 2 2 1 3 3 3 0 Spc7 kinetochore protein WD40 PF00400.32 CDJ48002.1 - 9.4e-28 95.9 25.3 0.00012 22.8 1.2 10.3 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ48002.1 - 7.7e-15 55.0 0.0 0.031 14.6 0.0 7.5 5 2 2 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CDJ48002.1 - 2.4e-05 24.7 1.3 8.2 7.1 0.0 6.3 7 0 0 7 7 7 2 PQQ-like domain Ge1_WD40 PF16529.5 CDJ48002.1 - 0.00026 20.1 0.0 0.037 13.0 0.0 3.3 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDJ48002.1 - 0.00081 19.3 0.0 0.023 14.6 0.0 2.9 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CDJ48002.1 - 0.0018 18.2 0.0 9.1 6.4 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 CDJ48002.1 - 0.0029 17.2 0.0 0.57 9.7 0.0 3.4 2 1 1 3 3 3 2 PQQ-like domain Nup160 PF11715.8 CDJ48002.1 - 0.025 13.2 0.1 4 5.9 0.0 2.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 CDJ48002.1 - 0.04 13.3 0.0 4.3 6.6 0.0 2.8 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Reg_prop PF07494.11 CDJ48002.1 - 0.058 13.6 0.2 44 4.8 0.0 4.2 4 0 0 4 4 4 0 Two component regulator propeller Glyco_hydro_77 PF02446.17 CDJ48003.1 - 2e-73 247.9 0.6 1.1e-72 245.5 0.6 1.8 1 1 0 1 1 1 1 4-alpha-glucanotransferase ING PF12998.7 CDJ48004.1 - 4.5 7.9 6.9 2.2 8.9 0.9 3.2 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding MPS2 PF17060.5 CDJ48004.1 - 7.3 5.7 11.9 11 5.1 4.6 2.4 2 0 0 2 2 2 0 Monopolar spindle protein 2 Ribosomal_60s PF00428.19 CDJ48005.1 - 9e-23 80.7 10.9 9e-23 80.7 10.9 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein ASFV_J13L PF05568.11 CDJ48005.1 - 2.1 8.1 5.0 0.85 9.3 3.0 1.4 2 0 0 2 2 2 0 African swine fever virus J13L protein Activator_LAG-3 PF11498.8 CDJ48006.1 - 0.0013 17.8 23.9 0.0013 17.8 23.9 2.5 2 0 0 2 2 1 1 Transcriptional activator LAG-3 Peptidase_S49_N PF08496.10 CDJ48006.1 - 0.015 15.3 3.1 0.015 15.3 3.1 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MAT1 PF06391.13 CDJ48006.1 - 0.22 11.4 35.3 0.031 14.1 14.7 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Pinin_SDK_memA PF04696.13 CDJ48006.1 - 1.7 8.7 44.6 0.34 11.0 15.6 2.3 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region BORG_CEP PF14957.6 CDJ48006.1 - 1.9 9.6 26.5 5.7 8.1 6.6 2.4 2 0 0 2 2 2 0 Cdc42 effector SpoIIP PF07454.11 CDJ48006.1 - 2.4 7.5 30.2 0.82 9.1 7.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CSRNP_N PF16019.5 CDJ48006.1 - 3.4 7.5 25.1 2.5 8.0 10.9 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus FAM176 PF14851.6 CDJ48006.1 - 4.6 6.9 19.9 3.1 7.5 4.0 2.5 2 0 0 2 2 2 0 FAM176 family NST1 PF13945.6 CDJ48006.1 - 5.2 7.1 45.1 8.1 6.5 20.9 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator SLC12 PF03522.15 CDJ48006.1 - 5.6 5.9 32.3 3.2 6.7 10.4 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Cwf_Cwc_15 PF04889.12 CDJ48006.1 - 6.4 6.4 29.0 5 6.8 7.3 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MPM1 PF17234.2 CDJ48006.1 - 7 6.9 36.3 0.37 11.0 10.2 2.5 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Miga PF10265.9 CDJ48006.1 - 8.1 5.3 29.0 0.52 9.2 8.4 2.0 2 0 0 2 2 2 0 Mitoguardin DUF5523 PF17661.1 CDJ48006.1 - 8.6 6.0 27.3 0.18 11.4 4.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Ribosomal_S26e PF01283.19 CDJ48007.1 - 0.05 14.1 0.9 0.061 13.8 0.9 1.2 1 0 0 1 1 1 0 Ribosomal protein S26e Glyco_transf_22 PF03901.17 CDJ48007.1 - 0.11 11.7 0.1 0.14 11.3 0.1 1.0 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family Adeno_PV PF03910.13 CDJ48007.1 - 0.14 10.8 3.7 0.14 10.8 3.7 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV Menin PF05053.13 CDJ48007.1 - 0.4 9.0 5.7 0.49 8.7 5.7 1.0 1 0 0 1 1 1 0 Menin RskA PF10099.9 CDJ48007.1 - 0.5 10.6 15.0 0.71 10.1 15.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ48007.1 - 3.8 7.4 22.2 4.3 7.2 22.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf_CCCH_4 PF18345.1 CDJ48009.1 - 3.3e-11 42.9 13.8 0.0055 16.7 1.4 3.8 3 1 0 3 3 3 3 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ48009.1 - 2.3e-09 36.8 17.7 0.00042 20.0 3.1 3.4 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ48009.1 - 8.3e-09 35.2 16.4 0.0073 16.2 3.0 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CDJ48009.1 - 2.9e-07 30.7 19.7 0.0019 18.6 2.2 3.4 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger RskA PF10099.9 CDJ48009.1 - 0.05 13.9 0.4 0.05 13.9 0.4 6.3 2 2 2 5 5 5 0 Anti-sigma-K factor rskA G0-G1_switch_2 PF15103.6 CDJ48009.1 - 0.064 13.7 0.3 0.064 13.7 0.3 4.9 3 1 2 5 5 5 0 G0/G1 switch protein 2 Hamartin PF04388.12 CDJ48009.1 - 0.091 11.4 30.2 0.017 13.8 14.7 2.2 2 0 0 2 2 2 0 Hamartin protein Trp_oprn_chp PF09534.10 CDJ48010.1 - 0.00012 22.0 3.8 0.00012 22.0 3.8 2.6 2 1 1 3 3 3 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FA_desaturase PF00487.24 CDJ48010.1 - 0.23 11.3 1.6 0.95 9.2 1.6 1.9 1 1 0 1 1 1 0 Fatty acid desaturase Peptidase_M56 PF05569.11 CDJ48010.1 - 9.9 5.3 19.9 0.03 13.5 8.3 2.0 1 1 1 2 2 2 0 BlaR1 peptidase M56 PDEase_I PF00233.19 CDJ48011.1 - 5.9e-08 32.7 0.0 5.9e-08 32.7 0.0 2.0 1 1 1 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DUF2052 PF09747.9 CDJ48011.1 - 0.012 15.8 12.6 0.012 15.7 12.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Ketoacyl-synt_2 PF13723.6 CDJ48011.1 - 0.037 13.6 16.1 0.043 13.4 16.1 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DDHD PF02862.17 CDJ48011.1 - 0.056 13.6 10.3 0.06 13.5 10.3 1.1 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 CDJ48011.1 - 0.062 12.1 12.8 0.064 12.0 12.8 1.1 1 0 0 1 1 1 0 Presenilin UPF0565 PF10561.9 CDJ48011.1 - 0.063 12.5 8.2 0.063 12.5 8.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF2828 PF11443.8 CDJ48011.1 - 0.068 11.3 10.6 0.068 11.3 10.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 CDJ48011.1 - 0.086 11.8 8.1 0.097 11.6 8.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 CDJ48011.1 - 0.096 12.1 6.9 0.11 11.9 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 CDJ48011.1 - 0.13 12.1 11.2 0.13 12.1 11.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AMP-binding PF00501.28 CDJ48011.1 - 0.14 10.7 4.7 0.16 10.5 4.7 1.0 1 0 0 1 1 1 0 AMP-binding enzyme Patched PF02460.18 CDJ48011.1 - 0.15 10.1 3.7 0.19 9.7 3.7 1.1 1 0 0 1 1 1 0 Patched family Serinc PF03348.15 CDJ48011.1 - 0.2 10.5 6.1 0.21 10.5 6.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) CobT PF06213.12 CDJ48011.1 - 0.29 10.5 21.0 0.36 10.2 21.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SID-1_RNA_chan PF13965.6 CDJ48011.1 - 0.36 9.2 6.3 0.38 9.1 6.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.10 CDJ48011.1 - 0.45 10.6 14.7 0.59 10.2 14.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TFIIA PF03153.13 CDJ48011.1 - 0.45 10.5 42.0 0.47 10.4 42.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ48011.1 - 0.5 8.2 14.6 0.47 8.3 14.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PP31 PF05311.11 CDJ48011.1 - 0.54 9.7 10.6 0.54 9.7 10.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) eIF-3_zeta PF05091.12 CDJ48011.1 - 0.56 9.1 18.4 0.6 9.0 18.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ48011.1 - 0.62 10.1 11.8 0.64 10.0 11.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 CDJ48011.1 - 0.7 9.8 5.9 0.81 9.6 5.9 1.2 1 0 0 1 1 1 0 N-glycosylation protein HCO3_cotransp PF00955.21 CDJ48011.1 - 0.75 8.5 4.5 0.81 8.4 4.5 1.0 1 0 0 1 1 1 0 HCO3- transporter family CSG2 PF16965.5 CDJ48011.1 - 1.2 8.0 7.0 1.2 8.0 7.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator CLN3 PF02487.17 CDJ48011.1 - 1.4 7.9 9.8 1.5 7.8 9.8 1.1 1 0 0 1 1 1 0 CLN3 protein Membralin PF09746.9 CDJ48011.1 - 1.4 7.9 10.9 1.5 7.8 10.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein Pex14_N PF04695.13 CDJ48011.1 - 1.9 9.1 22.6 2.6 8.7 22.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_23 PF13476.6 CDJ48011.1 - 1.9 9.0 22.3 2.3 8.7 22.3 1.3 1 0 0 1 1 1 0 AAA domain Zip PF02535.22 CDJ48011.1 - 1.9 7.6 3.5 1.9 7.6 3.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.9 CDJ48011.1 - 2.3 6.4 27.2 2.3 6.4 27.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 CDJ48011.1 - 3 7.6 14.7 3.4 7.4 14.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Connexin PF00029.19 CDJ48011.1 - 3.2 7.5 10.9 3.6 7.3 10.9 1.2 1 0 0 1 1 1 0 Connexin SpoIIP PF07454.11 CDJ48011.1 - 3.2 7.1 16.0 3.9 6.8 16.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ALMT PF11744.8 CDJ48011.1 - 3.4 6.4 12.8 3.5 6.3 12.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3276 PF11680.8 CDJ48011.1 - 3.5 7.8 12.0 4.7 7.3 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) CCDC53 PF10152.9 CDJ48011.1 - 3.8 7.9 17.7 4.8 7.6 17.7 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex YABBY PF04690.13 CDJ48011.1 - 4 8.0 12.8 4.8 7.7 12.8 1.2 1 0 0 1 1 1 0 YABBY protein HemX PF04375.14 CDJ48011.1 - 5.7 6.1 36.6 6.1 6.0 36.6 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Ctr PF04145.15 CDJ48011.1 - 6.1 7.4 9.7 7.2 7.2 9.7 1.2 1 0 0 1 1 1 0 Ctr copper transporter family BPL_N PF09825.9 CDJ48011.1 - 6.9 5.6 13.3 7.6 5.5 13.3 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal FAM60A PF15396.6 CDJ48011.1 - 7.1 6.6 12.8 8.3 6.3 12.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4446 PF14584.6 CDJ48011.1 - 7.1 6.6 12.2 8.6 6.3 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4667 PF15700.5 CDJ48014.1 - 0.019 15.1 4.9 0.64 10.1 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) TFIIS_M PF07500.14 CDJ48015.1 - 6.5e-22 78.1 0.1 1.7e-21 76.8 0.1 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CDJ48015.1 - 8.5e-19 67.1 3.0 1.8e-18 66.1 3.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CDJ48015.1 - 1.1e-08 34.9 0.5 2.4e-08 33.8 0.5 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain NAM-associated PF14303.6 CDJ48015.1 - 0.002 18.9 8.2 0.002 18.9 8.2 3.6 2 1 1 3 3 3 1 No apical meristem-associated C-terminal domain Elf1 PF05129.13 CDJ48015.1 - 0.0043 17.1 0.4 0.013 15.5 0.4 1.9 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Apt1 PF10351.9 CDJ48015.1 - 0.57 9.0 31.5 0.15 10.9 25.3 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain PNISR PF15996.5 CDJ48015.1 - 0.73 10.1 27.5 1.2 9.4 12.3 2.4 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Neur_chan_memb PF02932.16 CDJ48015.1 - 1.3 9.1 20.8 0.46 10.5 7.6 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ48015.1 - 6.8 5.3 29.2 0.73 8.5 17.7 2.2 2 0 0 2 2 2 0 Presenilin RskA PF10099.9 CDJ48017.1 - 1.1 9.5 64.4 0.069 13.4 10.9 3.2 1 1 2 3 3 3 0 Anti-sigma-K factor rskA TDRP PF15683.5 CDJ48018.1 - 0.00061 19.8 0.5 0.00061 19.8 0.5 3.3 3 1 1 4 4 3 1 Testis development-related protein MPM1 PF17234.2 CDJ48018.1 - 0.054 13.8 21.1 0.17 12.2 8.4 2.4 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 SAGA-Tad1 PF12767.7 CDJ48018.1 - 1.8 8.2 19.2 0.71 9.6 9.5 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit OmpH PF03938.14 CDJ48018.1 - 2.2 8.6 50.1 5.4 7.4 27.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) eIF-3_zeta PF05091.12 CDJ48018.1 - 2.2 7.1 26.9 0.17 10.8 8.4 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DivIC PF04977.15 CDJ48018.1 - 2.3 8.1 26.6 2 8.3 9.2 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF4770 PF15994.5 CDJ48018.1 - 3.2 8.0 15.6 3.8 7.7 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Vma12 PF11712.8 CDJ48018.1 - 4.2 7.4 7.6 10 6.2 1.0 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4647 PF15504.6 CDJ48018.1 - 5.6 6.0 21.1 5.7 5.9 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) Neur_chan_memb PF02932.16 CDJ48018.1 - 7.1 6.6 19.2 5.2 7.0 7.4 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LAM_C PF12544.8 CDJ48018.1 - 8.6 6.6 7.6 4.9 7.4 0.8 2.3 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Mito_fiss_reg PF05308.11 CDJ48020.1 - 0.095 12.8 3.1 0.11 12.6 3.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator TMEM171 PF15471.6 CDJ48020.1 - 0.57 9.1 3.5 0.74 8.7 3.5 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF3292 PF11696.8 CDJ48020.1 - 5.4 5.3 5.9 6.4 5.0 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) RskA PF10099.9 CDJ48020.1 - 6.6 7.0 24.7 11 6.3 24.7 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ48021.1 - 5.6e-06 26.8 0.0 1.2e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 Anti-sigma-K factor rskA PCI PF01399.27 CDJ48021.1 - 0.0045 17.5 0.3 0.0045 17.5 0.3 2.3 2 1 1 3 3 3 1 PCI domain TFIIA PF03153.13 CDJ48021.1 - 0.006 16.6 26.2 0.007 16.4 26.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ48021.1 - 0.022 13.7 9.0 0.024 13.6 9.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 CDJ48021.1 - 0.11 12.5 13.2 0.14 12.1 13.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ48021.1 - 0.35 10.9 5.6 0.43 10.6 5.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ48021.1 - 0.62 8.8 12.6 0.75 8.5 12.6 1.3 1 0 0 1 1 1 0 Presenilin AAA_23 PF13476.6 CDJ48021.1 - 2.1 8.8 14.3 3.1 8.2 14.3 1.3 1 0 0 1 1 1 0 AAA domain DUF4820 PF16091.5 CDJ48021.1 - 6.3 6.1 16.0 5.3 6.3 14.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) Spt20 PF12090.8 CDJ48023.1 - 0.42 10.2 61.1 0.48 10.0 19.9 3.7 3 0 0 3 3 3 0 Spt20 family EB1_binding PF05937.11 CDJ48024.1 - 0.0056 17.3 0.7 0.0071 17.0 0.7 1.1 1 0 0 1 1 1 1 EB-1 Binding Domain TFIIA PF03153.13 CDJ48024.1 - 1.9 8.4 32.5 2.4 8.1 32.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5427 PF10310.9 CDJ48024.1 - 2.3 7.1 20.4 2.9 6.7 20.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) MAT1 PF06391.13 CDJ48024.1 - 2.5 7.9 19.5 2.9 7.7 19.5 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Serinc PF03348.15 CDJ48024.1 - 3.6 6.4 10.5 5.4 5.8 10.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) CDK2AP PF09806.9 CDJ48024.1 - 5.6 7.0 22.7 6.5 6.7 22.7 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Senescence_reg PF04520.13 CDJ48024.1 - 8.7 7.2 14.7 9.7 7.0 14.7 1.1 1 0 0 1 1 1 0 Senescence regulator Ndc1_Nup PF09531.10 CDJ48024.1 - 8.8 4.9 17.0 9.7 4.7 17.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Metallophos PF00149.28 CDJ48026.1 - 2.3e-31 109.9 0.1 4.2e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CDJ48026.1 - 4.3e-15 55.8 0.0 9.4e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.17 CDJ48026.1 - 6.5e-10 38.3 5.6 0.0082 16.2 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ48026.1 - 3.8e-06 26.5 5.7 0.035 13.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ48026.1 - 0.0056 16.3 1.4 0.093 12.4 0.6 2.6 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 CDJ48026.1 - 0.041 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ48026.1 - 0.057 13.7 0.6 17 5.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ48026.1 - 0.099 13.5 0.4 4.6 8.3 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat NolB PF17398.2 CDJ48026.1 - 1.4 9.3 5.2 13 6.1 0.3 4.2 2 2 2 4 4 4 0 Nodulation protein NolB Apolipoprotein PF01442.18 CDJ48026.1 - 1.4 8.7 13.1 0.83 9.5 0.6 3.1 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Sporozoite_P67 PF05642.11 CDJ48027.1 - 0.00016 19.9 3.5 0.74 7.8 7.3 2.1 2 0 0 2 2 2 2 Sporozoite P67 surface antigen Apt1 PF10351.9 CDJ48027.1 - 0.00039 19.4 9.7 0.042 12.7 0.0 2.4 2 0 0 2 2 2 2 Golgi-body localisation protein domain DUF4667 PF15700.5 CDJ48027.1 - 0.00045 20.4 24.0 0.0088 16.2 0.8 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ48027.1 - 0.00053 19.7 2.4 0.00053 19.7 2.4 3.4 2 1 1 3 3 3 1 Spt20 family SPX PF03105.19 CDJ48027.1 - 0.0019 18.2 21.5 0.36 10.7 14.7 3.0 3 0 0 3 3 3 2 SPX domain Lin-8 PF03353.15 CDJ48027.1 - 0.019 14.6 17.7 0.17 11.4 0.4 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist MecA PF05389.12 CDJ48027.1 - 0.25 11.0 7.1 0.95 9.1 0.0 2.6 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) PA26 PF04636.13 CDJ48027.1 - 0.39 9.6 6.3 0.074 12.0 1.3 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) TFIIA PF03153.13 CDJ48027.1 - 0.56 10.1 54.6 0.019 15.0 2.7 3.0 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit Orf78 PF06024.12 CDJ48027.1 - 2.9 8.3 8.3 5.5 7.3 0.0 3.7 4 0 0 4 4 4 0 Orf78 (ac78) DUF2722 PF10846.8 CDJ48028.1 - 1.9e-05 23.8 13.1 1.9e-05 23.8 13.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ48028.1 - 4.6e-05 23.8 13.8 4.6e-05 23.8 13.8 9.5 2 1 3 5 5 2 2 Anti-sigma-K factor rskA Dpy19 PF10034.9 CDJ48028.1 - 0.00076 17.8 0.5 0.0011 17.3 0.5 1.2 1 0 0 1 1 1 1 Q-cell neuroblast polarisation eIF-3_zeta PF05091.12 CDJ48028.1 - 0.0011 18.0 3.3 0.0021 17.1 3.3 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex14_N PF04695.13 CDJ48028.1 - 0.0045 17.7 18.2 0.0045 17.7 18.2 5.3 4 1 1 5 5 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec6 PF06046.13 CDJ48028.1 - 0.034 12.5 3.4 0.065 11.6 3.4 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec6 CSG2 PF16965.5 CDJ48028.1 - 0.07 12.1 3.3 0.16 10.9 3.3 1.5 1 0 0 1 1 1 0 Ceramide synthase regulator Connexin PF00029.19 CDJ48028.1 - 0.086 12.6 3.1 0.19 11.5 2.1 2.0 2 0 0 2 2 2 0 Connexin DUF4770 PF15994.5 CDJ48028.1 - 0.14 12.4 7.3 0.7 10.1 7.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) ERbeta_N PF12497.8 CDJ48028.1 - 0.15 11.8 5.7 0.5 10.2 5.7 1.9 1 0 0 1 1 1 0 Estrogen receptor beta SID-1_RNA_chan PF13965.6 CDJ48028.1 - 0.19 10.1 2.8 0.42 9.0 2.8 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Sarcoglycan_2 PF05510.13 CDJ48028.1 - 0.37 9.5 4.2 0.65 8.7 4.2 1.3 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Mlh1_C PF16413.5 CDJ48028.1 - 0.99 8.7 10.2 0.13 11.6 5.2 2.0 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus MecA PF05389.12 CDJ48028.1 - 2.7 7.6 9.7 0.079 12.6 2.6 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) CK_II_beta PF01214.18 CDJ48030.1 - 1.4e-25 90.2 0.0 3.1e-25 89.1 0.0 1.5 2 0 0 2 2 2 1 Casein kinase II regulatory subunit RskA PF10099.9 CDJ48030.1 - 0.01 16.1 2.3 0.014 15.7 2.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA AveC_like PF17198.4 CDJ48030.1 - 0.056 12.9 1.5 0.075 12.5 1.5 1.1 1 0 0 1 1 1 0 Spirocyclase AveC-like Radial_spoke PF04712.12 CDJ48030.1 - 0.21 10.5 7.4 0.28 10.1 7.4 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 CDJ48030.1 - 0.91 7.5 6.8 1.1 7.3 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 CDJ48030.1 - 6.1 7.3 8.7 6.6 7.2 7.4 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2722 PF10846.8 CDJ48031.1 - 8.1e-05 21.8 61.7 0.0027 16.7 7.1 3.9 4 0 0 4 4 4 3 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ48031.1 - 0.0061 16.2 17.6 0.0061 16.2 17.6 4.4 4 1 1 5 5 4 1 Spt20 family RskA PF10099.9 CDJ48031.1 - 0.008 16.5 10.3 0.008 16.5 10.3 5.0 1 1 3 4 4 3 1 Anti-sigma-K factor rskA Eapp_C PF10238.9 CDJ48031.1 - 0.4 10.8 23.9 0.53 10.4 3.5 3.7 4 0 0 4 4 4 0 E2F-associated phosphoprotein CLN3 PF02487.17 CDJ48031.1 - 0.65 9.0 12.4 1.1 8.2 4.0 2.5 2 0 0 2 2 2 0 CLN3 protein Peroxin-13_N PF04088.13 CDJ48031.1 - 1.4 9.2 16.5 3.1 8.1 1.4 4.4 4 0 0 4 4 4 0 Peroxin 13, N-terminal region DUF4366 PF14283.6 CDJ48031.1 - 2.5 8.1 17.9 0.64 10.1 2.8 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4366) DUF4834 PF16118.5 CDJ48031.1 - 3.7 8.6 39.6 0.46 11.5 2.5 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4834) DUF5427 PF10310.9 CDJ48031.1 - 4.1 6.3 26.9 5.2 5.9 5.9 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5427) DUF4407 PF14362.6 CDJ48031.1 - 5 6.4 45.6 0.12 11.7 2.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) O-antigen_lig PF13425.6 CDJ48031.1 - 5.5 5.7 4.9 8.8 5.0 0.6 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein SUIM_assoc PF16619.5 CDJ48032.1 - 0.00011 22.2 1.1 0.00011 22.2 1.1 5.5 3 1 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 DUF3682 PF12446.8 CDJ48032.1 - 0.00083 19.8 15.6 0.00083 19.8 15.6 9.4 7 3 1 8 8 8 1 Protein of unknown function (DUF3682) Spore_III_AF PF09581.10 CDJ48032.1 - 0.0012 19.0 13.6 1.3e+02 2.5 7.4 4.5 4 1 0 4 4 4 0 Stage III sporulation protein AF (Spore_III_AF) Spt20 PF12090.8 CDJ48032.1 - 0.0025 17.5 63.5 0.015 15.0 12.6 3.8 5 0 0 5 5 5 3 Spt20 family DUF5349 PF17298.2 CDJ48032.1 - 0.0026 17.6 11.0 0.0026 17.6 11.0 4.8 5 0 0 5 5 5 2 Family of unknown function (DUF5349) NUC153 PF08159.12 CDJ48032.1 - 0.03 14.1 1.1 0.077 12.8 0.1 2.1 2 0 0 2 2 2 0 NUC153 domain TFIIF_alpha PF05793.12 CDJ48034.1 - 1.4 7.5 33.0 0.0065 15.1 24.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mem_trans PF03547.18 CDJ48034.1 - 1.8 6.9 9.8 2.8 6.2 9.8 1.3 1 0 0 1 1 1 0 Membrane transport protein Pkinase PF00069.25 CDJ48035.1 - 7.4e-32 110.7 0.0 8.3e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ48035.1 - 1.3e-14 54.2 0.0 1.4e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ48035.1 - 2.4e-06 27.1 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ48035.1 - 6.6e-05 21.9 0.0 6.6e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ48035.1 - 0.0059 16.6 0.0 0.0074 16.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ48035.1 - 0.014 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SARAF PF06682.12 CDJ48036.1 - 5.4 6.6 25.2 0.24 11.0 19.4 1.7 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis MCM_bind PF09739.9 CDJ48037.1 - 0.0012 17.3 30.8 0.0012 17.3 30.8 2.0 1 1 1 2 2 2 1 Mini-chromosome maintenance replisome factor Cwf_Cwc_15 PF04889.12 CDJ48037.1 - 2.1 8.0 54.1 3.1 7.5 54.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PGM_PMM_II PF02879.16 CDJ48038.1 - 1.4e-08 35.2 0.1 4.6e-08 33.6 0.1 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Spt20 PF12090.8 CDJ48038.1 - 0.017 14.8 2.0 0.018 14.7 2.0 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ48038.1 - 0.046 12.7 0.1 0.046 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Inj_translocase PF16928.5 CDJ48038.1 - 0.052 13.0 4.3 0.081 12.4 4.3 1.3 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome TraG_N PF07916.11 CDJ48038.1 - 0.16 10.8 2.3 0.21 10.4 2.3 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2489 PF10675.9 CDJ48038.1 - 1.2 9.1 6.5 1.8 8.5 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Pkinase PF00069.25 CDJ48039.1 - 4.2e-63 213.2 0.0 4.9e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ48039.1 - 7e-32 110.7 0.0 8.9e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ48039.1 - 5.4e-07 29.2 0.0 8.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ48039.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ48039.1 - 0.019 14.9 0.0 0.094 12.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ48039.1 - 0.028 13.2 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 CDJ48039.1 - 0.044 12.7 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CDJ48039.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Lon_C PF05362.13 CDJ48040.1 - 9.8e-24 84.0 0.1 1.4e-23 83.5 0.1 1.2 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 CDJ48040.1 - 0.00027 20.8 0.1 0.0004 20.2 0.1 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Pro-rich PF15240.6 CDJ48040.1 - 0.00073 19.9 33.3 0.0008 19.7 33.3 1.1 1 0 0 1 1 1 1 Proline-rich Gly-zipper_OmpA PF13436.6 CDJ48040.1 - 1.4 8.7 6.3 14 5.5 0.0 2.8 3 0 0 3 3 3 0 Glycine-zipper domain Hamartin PF04388.12 CDJ48041.1 - 0.058 12.1 47.9 0.072 11.8 47.9 1.0 1 0 0 1 1 1 0 Hamartin protein DUF2052 PF09747.9 CDJ48041.1 - 0.17 12.0 32.5 0.23 11.6 32.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TFIIA PF03153.13 CDJ48041.1 - 0.24 11.3 74.4 0.35 10.8 74.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Caldesmon PF02029.15 CDJ48041.1 - 0.71 8.6 42.7 0.92 8.2 42.7 1.2 1 0 0 1 1 1 0 Caldesmon PAT1 PF09770.9 CDJ48041.1 - 0.85 7.8 51.8 0.99 7.6 51.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.6 CDJ48041.1 - 1.1 9.7 33.4 1.5 9.3 33.4 1.1 1 0 0 1 1 1 0 AAA domain SOBP PF15279.6 CDJ48041.1 - 1.3 9.6 53.7 1.8 9.1 53.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RAP1 PF07218.11 CDJ48041.1 - 1.4 7.1 19.5 2.1 6.5 19.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDK5_activator PF03261.15 CDJ48041.1 - 3.9 6.9 45.2 4.9 6.6 45.2 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein AAA PF00004.29 CDJ48042.1 - 4.3e-07 30.4 0.0 1.1e-06 29.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Lon_C PF05362.13 CDJ48042.1 - 4.9e-07 29.5 0.0 9.2e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ClpB_D2-small PF10431.9 CDJ48042.1 - 0.053 13.6 0.2 0.091 12.8 0.2 1.4 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_2 PF07724.14 CDJ48042.1 - 0.076 13.1 0.0 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) SLC3A2_N PF16028.5 CDJ48042.1 - 0.18 11.3 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Presenilin PF01080.17 CDJ48044.1 - 0.21 10.3 22.5 0.23 10.2 22.5 1.0 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 CDJ48044.1 - 0.69 8.9 16.1 0.74 8.8 16.1 1.0 1 0 0 1 1 1 0 CLN3 protein FAM176 PF14851.6 CDJ48044.1 - 1.2 8.8 10.8 1.7 8.3 10.8 1.2 1 0 0 1 1 1 0 FAM176 family Afi1 PF07792.12 CDJ48044.1 - 2.3 8.7 17.4 2.5 8.6 17.4 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RR_TM4-6 PF06459.12 CDJ48044.1 - 2.3 7.9 20.2 2.6 7.8 20.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ48044.1 - 3.2 6.5 19.7 3.7 6.3 19.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ48044.1 - 3.7 6.5 22.2 4 6.3 22.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CCDC53 PF10152.9 CDJ48044.1 - 3.9 7.9 20.3 4.4 7.7 20.3 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF789 PF05623.12 CDJ48044.1 - 4 7.0 18.5 4.8 6.8 18.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF789) V_ATPase_I PF01496.19 CDJ48044.1 - 4.2 5.2 23.4 5 4.9 23.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 CDJ48044.1 - 4.6 6.1 12.8 5.3 5.9 12.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CobT PF06213.12 CDJ48044.1 - 4.7 6.5 29.2 5.8 6.2 29.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIP PF07454.11 CDJ48044.1 - 5 6.5 21.9 6 6.2 21.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF3381 PF11861.8 CDJ48044.1 - 5.2 6.8 29.4 6.2 6.6 29.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF2828 PF11443.8 CDJ48044.1 - 6 4.8 22.4 6.5 4.7 22.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Med19 PF10278.9 CDJ48044.1 - 6.3 6.7 15.5 6.9 6.6 15.5 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_U57 PF05582.12 CDJ48044.1 - 6.3 6.0 15.8 7.6 5.7 15.8 1.1 1 0 0 1 1 1 0 YabG peptidase U57 SID-1_RNA_chan PF13965.6 CDJ48044.1 - 7.6 4.8 11.0 7.9 4.8 11.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDHD PF02862.17 CDJ48044.1 - 8.1 6.5 18.7 9.9 6.2 18.7 1.1 1 0 0 1 1 1 0 DDHD domain CSG2 PF16965.5 CDJ48044.1 - 8.9 5.1 12.6 9.2 5.1 12.6 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Connexin PF00029.19 CDJ48044.1 - 9.8 5.9 16.5 12 5.5 16.5 1.2 1 0 0 1 1 1 0 Connexin DUF4746 PF15928.5 CDJ48044.1 - 10 5.5 14.7 12 5.3 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) LysM PF01476.20 CDJ48045.1 - 9.9e-09 35.1 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 LysM domain Spt20 PF12090.8 CDJ48045.1 - 0.036 13.7 7.6 0.056 13.0 7.6 1.3 1 0 0 1 1 1 0 Spt20 family SOG2 PF10428.9 CDJ48046.1 - 4.3e-05 22.9 10.6 4.3e-05 22.9 10.6 2.2 2 0 0 2 2 2 1 RAM signalling pathway protein Mem_trans PF03547.18 CDJ48046.1 - 0.0035 15.8 0.2 0.0035 15.8 0.2 1.4 2 0 0 2 2 1 1 Membrane transport protein Spt20 PF12090.8 CDJ48046.1 - 0.0058 16.3 47.1 0.021 14.4 16.1 2.2 2 0 0 2 2 2 2 Spt20 family SPX PF03105.19 CDJ48046.1 - 0.0095 15.9 12.8 0.0088 16.0 6.1 2.4 2 0 0 2 2 2 1 SPX domain AF-4 PF05110.13 CDJ48046.1 - 0.02 13.0 27.0 0.0088 14.2 18.7 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein RAP1 PF07218.11 CDJ48046.1 - 0.035 12.4 9.8 0.061 11.6 9.8 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Lin-8 PF03353.15 CDJ48046.1 - 0.038 13.6 22.0 0.067 12.7 13.3 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist FAM60A PF15396.6 CDJ48046.1 - 0.067 13.2 10.2 0.19 11.7 5.6 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Peptidase_S64 PF08192.11 CDJ48046.1 - 0.091 11.2 18.1 0.023 13.2 12.0 2.0 2 0 0 2 2 2 0 Peptidase family S64 Mit_ribos_Mrp51 PF11709.8 CDJ48046.1 - 0.097 12.2 13.4 0.064 12.8 4.9 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit Paf1 PF03985.13 CDJ48046.1 - 0.14 11.1 23.6 0.28 10.1 12.9 2.2 2 0 0 2 2 2 0 Paf1 Neur_chan_memb PF02932.16 CDJ48046.1 - 0.18 11.9 14.5 3.4 7.6 0.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 CDJ48046.1 - 0.23 8.5 19.7 0.023 11.9 12.3 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 CDJ48046.1 - 0.24 10.1 20.3 1.2 7.9 0.6 2.1 2 0 0 2 2 2 0 Presenilin DUF572 PF04502.13 CDJ48046.1 - 0.25 10.9 18.1 2.5 7.7 11.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Apt1 PF10351.9 CDJ48046.1 - 0.28 10.0 15.5 0.066 12.1 10.0 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 CDJ48046.1 - 0.34 9.5 17.2 0.065 11.9 8.3 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup MPM1 PF17234.2 CDJ48046.1 - 0.43 10.8 19.7 1.7 8.9 10.0 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 MAT1 PF06391.13 CDJ48046.1 - 0.44 10.3 25.1 0.59 9.9 13.6 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 PAT1 PF09770.9 CDJ48046.1 - 1 7.5 26.2 0.47 8.7 2.0 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 UPF0231 PF06062.11 CDJ48046.1 - 1.1 9.6 14.5 0.086 13.1 6.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) Plasmodium_Vir PF05795.11 CDJ48046.1 - 1.3 8.4 12.8 0.14 11.5 4.2 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.12 CDJ48046.1 - 2 7.3 18.8 0.2 10.6 1.4 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ48046.1 - 2.2 7.2 17.2 2.7 6.9 10.0 2.1 2 0 0 2 2 2 0 Solute carrier family 12 BORG_CEP PF14957.6 CDJ48046.1 - 2.4 9.4 17.4 11 7.2 12.6 2.4 2 0 0 2 2 2 0 Cdc42 effector SR-25 PF10500.9 CDJ48046.1 - 2.9 7.4 37.5 0.33 10.5 29.2 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Miga PF10265.9 CDJ48046.1 - 3.1 6.7 19.6 0.46 9.4 14.5 2.1 2 0 0 2 2 2 0 Mitoguardin SARAF PF06682.12 CDJ48046.1 - 3.2 7.3 24.5 0.67 9.5 6.4 2.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Mcm10 PF09332.11 CDJ48046.1 - 5.2 6.4 24.4 4.6 6.6 0.5 2.2 2 0 0 2 2 2 0 Mcm10 replication factor Herpes_pp85 PF04637.12 CDJ48046.1 - 5.7 5.2 9.0 10 4.4 9.0 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4746 PF15928.5 CDJ48046.1 - 7.4 5.9 10.7 5.1 6.4 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) V_ATPase_I PF01496.19 CDJ48046.1 - 9.3 4.0 14.5 4.2 5.2 6.2 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Cwf_Cwc_15 PF04889.12 CDJ48047.1 - 3.1 7.5 36.5 0.11 12.3 10.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 CDJ48050.1 - 0.00027 21.1 20.2 0.00027 21.1 20.2 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit RuBisCO_large PF00016.20 CDJ48050.1 - 0.033 13.4 1.4 0.072 12.3 1.4 1.5 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Hira PF07569.11 CDJ48050.1 - 0.14 11.9 0.0 0.14 11.9 0.0 2.4 3 0 0 3 3 2 0 TUP1-like enhancer of split Lin-8 PF03353.15 CDJ48050.1 - 0.16 11.5 14.2 0.28 10.7 14.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ48050.1 - 0.34 9.7 11.2 0.077 11.8 8.3 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Rxt3 PF08642.10 CDJ48050.1 - 0.5 11.1 2.9 0.97 10.2 2.9 1.5 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Macoilin PF09726.9 CDJ48050.1 - 0.52 8.8 9.4 1.1 7.8 9.4 1.5 1 0 0 1 1 1 0 Macoilin family DUF1645 PF07816.11 CDJ48050.1 - 0.73 10.4 15.1 0.056 14.0 9.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) EIIBC-GUT_N PF03612.14 CDJ48050.1 - 0.83 9.4 6.7 1.6 8.4 6.7 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Gti1_Pac2 PF09729.9 CDJ48050.1 - 0.86 9.7 5.2 1.7 8.7 5.2 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family TRM13 PF05206.14 CDJ48050.1 - 0.94 8.9 9.3 1.5 8.3 9.3 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 FAM176 PF14851.6 CDJ48050.1 - 1.3 8.7 5.9 2.8 7.6 5.9 1.5 1 0 0 1 1 1 0 FAM176 family Herpes_pp85 PF04637.12 CDJ48050.1 - 1.6 7.0 3.2 2.7 6.3 3.2 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) AIF_C PF14721.6 CDJ48050.1 - 2.8 8.3 4.8 7.5 6.9 4.8 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term OATP PF03137.20 CDJ48050.1 - 2.8 6.1 3.9 4.2 5.5 3.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Connexin PF00029.19 CDJ48050.1 - 3.8 7.2 5.3 6.6 6.4 5.3 1.3 1 0 0 1 1 1 0 Connexin SPX PF03105.19 CDJ48050.1 - 4.1 7.2 19.5 0.78 9.6 15.1 1.8 2 0 0 2 2 2 0 SPX domain Tim54 PF11711.8 CDJ48050.1 - 5.2 5.8 6.6 9.1 4.9 6.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 CDJ48050.1 - 7.6 6.3 8.3 13 5.5 8.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 CDJ48050.1 - 7.7 5.9 10.5 12 5.3 10.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Ku PF02735.16 CDJ48051.1 - 0.00034 20.4 0.0 0.0067 16.2 0.0 2.2 1 1 1 2 2 2 1 Ku70/Ku80 beta-barrel domain DUF2722 PF10846.8 CDJ48051.1 - 0.0025 16.9 1.2 0.0034 16.4 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ48051.1 - 0.0044 17.1 8.0 0.008 16.2 8.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ48051.1 - 0.056 13.0 11.3 0.09 12.4 11.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ48051.1 - 0.92 10.5 2.8 1.8 9.6 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Ribosomal_60s PF00428.19 CDJ48051.1 - 1.2 9.8 49.1 4 8.1 11.8 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein SLC12 PF03522.15 CDJ48053.1 - 0.011 14.8 11.9 0.014 14.4 11.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MDM10 PF12519.8 CDJ48053.1 - 0.4 9.5 13.6 0.58 9.0 13.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Suf PF05843.14 CDJ48053.1 - 0.72 9.8 22.7 1.3 8.9 22.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LPG_synthase_TM PF03706.13 CDJ48053.1 - 2.2 7.8 10.3 0.058 12.9 3.2 1.8 1 1 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region Hid1 PF12722.7 CDJ48053.1 - 4.8 5.2 15.3 6.2 4.8 15.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 CDJ48053.1 - 8.3 5.3 8.3 13 4.6 8.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4551 PF15087.6 CDJ48053.1 - 9.8 4.9 19.4 13 4.5 19.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF908 PF06012.12 CDJ48053.1 - 10 5.4 14.5 4.7 6.5 12.3 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) XPA_C PF05181.12 CDJ48054.1 - 0.00036 20.4 0.0 0.00075 19.4 0.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus Ion_trans_N PF08412.10 CDJ48054.1 - 0.26 10.9 0.0 0.26 10.9 0.0 2.5 2 0 0 2 2 2 0 Ion transport protein N-terminal PAT1 PF09770.9 CDJ48054.1 - 0.64 8.2 66.3 0.57 8.4 31.7 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CWC25 PF12542.8 CDJ48055.1 - 2.3e-11 44.5 2.3 2.3e-11 44.5 2.3 6.0 3 2 0 3 3 3 1 Pre-mRNA splicing factor SR-25 PF10500.9 CDJ48055.1 - 6.5e-05 22.6 95.3 0.0083 15.8 57.4 3.4 2 1 1 3 3 3 3 Nuclear RNA-splicing-associated protein TAF4 PF05236.14 CDJ48055.1 - 0.0021 17.9 7.4 0.0021 17.9 7.4 3.2 1 1 1 2 2 2 1 Transcription initiation factor TFIID component TAF4 family DUF755 PF05501.11 CDJ48055.1 - 0.003 17.8 37.9 0.003 17.8 37.9 6.0 4 2 1 5 5 5 1 Domain of unknown function (DUF755) IMUP PF15761.5 CDJ48055.1 - 0.026 15.2 3.2 0.026 15.2 3.2 4.6 3 1 1 4 4 4 0 Immortalisation up-regulated protein SARAF PF06682.12 CDJ48055.1 - 0.25 11.0 34.1 0.015 15.0 9.7 2.7 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis PI3K_1B_p101 PF10486.9 CDJ48055.1 - 1.3 6.7 33.4 0.031 12.1 26.8 1.6 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Dehydrin PF00257.19 CDJ48055.1 - 2.4 8.7 60.4 6.2 7.4 3.2 4.2 2 1 0 3 3 3 0 Dehydrin Helicase_C PF00271.31 CDJ48056.1 - 2.5e-14 53.6 0.0 2.5e-14 53.6 0.0 3.8 4 2 1 5 5 5 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ48056.1 - 2e-13 50.5 9.8 7.1e-09 35.7 2.1 4.2 3 1 0 3 3 3 2 DEAD/DEAH box helicase INSIG PF07281.12 CDJ48056.1 - 0.019 14.6 0.9 0.019 14.6 0.9 4.0 4 1 0 4 4 4 0 Insulin-induced protein (INSIG) Glyco_hydro_9 PF00759.19 CDJ48057.1 - 0.083 12.3 5.6 0.17 11.2 5.6 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Grg1 PF11034.8 CDJ48058.1 - 0.095 12.9 18.1 1.1 9.5 7.4 2.5 1 1 1 2 2 2 0 Glucose-repressible protein Grg1 CUTL PF16557.5 CDJ48058.1 - 0.1 12.8 3.1 3.9 7.7 0.4 2.4 2 0 0 2 2 2 0 CUT1-like DNA-binding domain of SATB DAGK_cat PF00781.24 CDJ48058.1 - 0.16 11.6 7.0 1.5 8.4 0.6 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Asp-B-Hydro_N PF05279.11 CDJ48058.1 - 0.58 10.2 18.4 0.82 9.7 18.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf_CopZ PF18423.1 CDJ48058.1 - 0.76 9.8 6.4 7.1 6.7 1.0 2.4 2 0 0 2 2 2 0 Zinc binding domain CelTOS PF18659.1 CDJ48058.1 - 0.93 9.9 9.1 2.3 8.6 1.2 2.1 2 0 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites SSPI PF14098.6 CDJ48058.1 - 1 9.5 4.8 15 5.9 0.7 2.4 2 0 0 2 2 2 0 Small, acid-soluble spore protein I hDGE_amylase PF14701.6 CDJ48058.1 - 2.7 7.0 8.2 3.1 6.8 8.2 1.0 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Ndc1_Nup PF09531.10 CDJ48058.1 - 3.5 6.2 7.9 4.1 6.0 7.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAC3 PF12209.8 CDJ48058.1 - 4.4 7.6 16.8 2.1 8.6 3.4 2.8 3 0 0 3 3 3 0 Leucine permease transcriptional regulator helical domain Spore_III_AF PF09581.10 CDJ48058.1 - 5.5 7.0 17.3 3.2 7.7 2.9 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Hydin_ADK PF17213.3 CDJ48058.1 - 5.6 7.2 11.0 7.2 6.8 11.0 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RNase_J_C PF17770.1 CDJ48058.1 - 5.9 8.0 14.0 14 6.8 1.7 2.6 2 1 0 2 2 2 0 Ribonuclease J C-terminal domain CTD_bind PF04818.13 CDJ48058.1 - 6.6 7.6 6.7 20 6.1 1.3 2.2 2 0 0 2 2 2 0 RNA polymerase II-binding domain. ROK PF00480.20 CDJ48058.1 - 7.7 5.9 9.4 5.7 6.3 1.8 2.1 1 1 1 2 2 2 0 ROK family motB PF17613.2 CDJ48058.1 - 8.8 6.2 10.3 13 5.6 2.3 2.1 1 1 1 2 2 2 0 Modifier of transcription N2227 PF07942.12 CDJ48059.1 - 2.9e-29 102.1 0.3 6.4e-29 101.0 0.0 1.6 2 0 0 2 2 2 1 N2227-like protein CDC27 PF09507.10 CDJ48059.1 - 0.021 14.2 16.8 0.026 13.9 16.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Exonuc_VII_L PF02601.15 CDJ48059.1 - 0.025 14.1 13.1 0.034 13.7 13.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PSII_Pbs27 PF13326.6 CDJ48059.1 - 0.04 14.3 0.3 0.096 13.0 0.3 1.7 1 0 0 1 1 1 0 Photosystem II Pbs27 PepSY_TM_like_2 PF16357.5 CDJ48059.1 - 3.5 7.6 8.3 5.3 7.0 8.3 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like Hydin_ADK PF17213.3 CDJ48059.1 - 7.7 6.7 15.5 11 6.2 15.5 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Sin_N PF04801.13 CDJ48059.1 - 8.6 5.5 32.9 13 4.9 32.9 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region PAT1 PF09770.9 CDJ48059.1 - 8.8 4.5 35.0 11 4.1 35.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ48061.1 - 0.031 13.9 53.6 0.33 10.5 24.7 3.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein SID-1_RNA_chan PF13965.6 CDJ48062.1 - 0.0067 14.9 0.2 0.008 14.6 0.2 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Glyco_hydro_9 PF00759.19 CDJ48062.1 - 0.053 12.9 13.3 0.059 12.8 13.3 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 UPF0560 PF10577.9 CDJ48062.1 - 0.14 10.6 7.1 0.15 10.5 7.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Apt1 PF10351.9 CDJ48062.1 - 0.56 9.0 7.3 0.54 9.0 7.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MTTB PF06253.11 CDJ48062.1 - 0.77 7.7 13.3 0.97 7.3 13.3 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Tic110 PF16940.5 CDJ48062.1 - 1.5 7.2 8.4 1.6 7.1 8.4 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter BAF1_ABF1 PF04684.13 CDJ48062.1 - 1.5 7.8 9.6 2 7.4 9.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PMSI1 PF15322.6 CDJ48062.1 - 1.7 8.0 8.2 2 7.8 8.2 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Presenilin PF01080.17 CDJ48062.1 - 3.7 6.2 6.3 3.9 6.1 6.3 1.1 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 CDJ48063.1 - 0.0022 18.3 14.3 0.0022 18.3 14.3 5.7 3 2 0 4 4 4 2 Anti-sigma-K factor rskA DUF5327 PF17261.2 CDJ48063.1 - 0.02 15.6 9.2 0.02 15.6 9.2 6.3 5 2 1 6 6 6 0 Family of unknown function (DUF5327) DUF572 PF04502.13 CDJ48063.1 - 0.1 12.2 50.1 0.24 11.0 3.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF572) SDA1 PF05285.12 CDJ48063.1 - 0.56 9.6 50.2 0.2 11.1 10.9 2.6 2 1 0 2 2 2 0 SDA1 NPR3 PF03666.13 CDJ48063.1 - 1.2 7.9 51.1 0.14 10.9 22.3 3.2 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 Coilin_N PF15862.5 CDJ48063.1 - 1.3 8.8 0.0 1.3 8.8 0.0 6.0 5 2 1 6 6 6 0 Coilin N-terminus PAT1 PF09770.9 CDJ48063.1 - 4.7 5.4 92.7 0.25 9.6 14.1 3.1 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ48064.1 - 0.0041 16.8 28.2 0.0041 16.8 28.2 8.2 4 3 3 8 8 8 1 Nuclear RNA-splicing-associated protein FAM199X PF15814.5 CDJ48065.1 - 5.5 6.0 9.6 6.5 5.7 9.6 1.2 1 0 0 1 1 1 0 Protein family FAM199X PNISR PF15996.5 CDJ48066.1 - 2.1 8.6 25.1 0.65 10.2 13.4 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR RskA PF10099.9 CDJ48066.1 - 2.5 8.4 25.0 0.26 11.6 15.3 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ48067.1 - 1.7e-05 25.2 0.0 2.8e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Anti-sigma-K factor rskA Mitofilin PF09731.9 CDJ48067.1 - 0.00083 18.3 3.3 0.001 18.0 3.3 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein VirB8 PF04335.13 CDJ48067.1 - 0.0022 17.9 1.9 0.0022 17.9 1.9 2.0 1 1 0 2 2 2 1 VirB8 protein EMP24_GP25L PF01105.24 CDJ48067.1 - 0.005 16.8 0.3 0.0054 16.7 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ashwin PF15323.6 CDJ48067.1 - 0.0061 16.6 8.0 0.0078 16.3 8.0 1.3 1 0 0 1 1 1 1 Developmental protein Ntox30 PF15532.6 CDJ48067.1 - 0.089 13.2 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 Bacterial toxin 30 60KD_IMP PF02096.20 CDJ48067.1 - 0.75 9.7 6.0 0.99 9.3 6.0 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein SR-25 PF10500.9 CDJ48067.1 - 0.93 9.1 31.1 0.51 9.9 7.4 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.19 CDJ48067.1 - 1.1 9.9 14.0 1.8 9.2 14.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ48068.1 - 0.028 14.4 63.5 0.036 14.1 63.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 CDJ48068.1 - 0.3 9.4 5.3 0.29 9.5 5.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.10 CDJ48068.1 - 0.63 10.1 18.6 0.022 14.8 12.3 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal LMBR1 PF04791.16 CDJ48068.1 - 1 8.2 10.3 1 8.2 10.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein VIR_N PF15912.5 CDJ48068.1 - 2.6 7.6 22.7 3.9 7.0 22.7 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Spem1 PF15670.5 CDJ48068.1 - 5.6 6.5 15.5 1.3 8.5 12.4 1.5 2 0 0 2 2 2 0 Spermatid maturation protein 1 Hamartin PF04388.12 CDJ48068.1 - 8.5 4.9 31.0 9.6 4.7 31.0 1.1 1 0 0 1 1 1 0 Hamartin protein PRCC PF10253.9 CDJ48070.1 - 3.5e-06 28.0 2.6 3.5e-06 28.0 2.6 2.0 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Trypan_glycop_C PF10659.9 CDJ48070.1 - 0.0068 16.8 5.3 0.021 15.2 1.7 2.2 2 0 0 2 2 2 1 Trypanosome variant surface glycoprotein C-terminal domain DUF3391 PF11871.8 CDJ48070.1 - 0.021 15.4 2.4 0.021 15.4 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) SR-25 PF10500.9 CDJ48070.1 - 0.033 13.8 22.9 0.094 12.3 22.9 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ48070.1 - 0.093 11.6 11.4 0.11 11.3 11.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 CDJ48070.1 - 0.11 11.2 13.2 0.12 11.0 13.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2126 PF09899.9 CDJ48070.1 - 0.11 10.5 4.7 0.14 10.2 4.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF3984 PF13136.6 CDJ48070.1 - 0.22 10.9 21.1 0.32 10.4 21.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF719 PF05334.13 CDJ48070.1 - 0.25 11.5 11.9 0.056 13.6 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DDRGK PF09756.9 CDJ48070.1 - 0.29 10.7 15.9 0.034 13.7 6.1 2.1 2 0 0 2 2 2 0 DDRGK domain Peptidase_S49_N PF08496.10 CDJ48070.1 - 0.78 9.8 6.1 0.96 9.5 1.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SLC12 PF03522.15 CDJ48070.1 - 1 8.3 15.4 1.4 7.9 15.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 V_ATPase_I PF01496.19 CDJ48070.1 - 1.8 6.3 12.4 3 5.6 12.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Serinc PF03348.15 CDJ48070.1 - 2.4 7.0 7.7 3.3 6.6 7.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.16 CDJ48070.1 - 2.5 8.1 15.5 3.5 7.6 15.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CSG2 PF16965.5 CDJ48070.1 - 4.3 6.2 6.9 5.8 5.8 6.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Peroxin-3 PF04882.12 CDJ48070.1 - 4.5 6.2 19.4 6 5.7 19.4 1.1 1 0 0 1 1 1 0 Peroxin-3 DUF1835 PF08874.10 CDJ48070.1 - 4.7 7.4 11.8 0.11 12.7 3.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) CsoSCA PF08936.10 CDJ48072.1 - 0.075 11.7 1.1 0.15 10.7 0.2 1.7 1 1 1 2 2 2 0 Carboxysome Shell Carbonic Anhydrase Rtf2 PF04641.12 CDJ48073.1 - 0.0056 16.1 8.5 0.007 15.8 8.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger Elong_Iki1 PF10483.9 CDJ48073.1 - 0.011 15.3 5.6 0.013 15.0 5.6 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 Presenilin PF01080.17 CDJ48073.1 - 0.014 14.2 16.3 0.018 13.9 16.3 1.1 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 CDJ48073.1 - 0.042 13.5 10.2 0.22 11.1 2.3 2.1 2 0 0 2 2 2 0 FAM176 family WRNPLPNID PF15017.6 CDJ48073.1 - 0.077 13.9 14.4 0.12 13.3 1.5 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DUF913 PF06025.12 CDJ48073.1 - 0.086 11.8 6.1 0.11 11.4 6.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Otopetrin PF03189.13 CDJ48073.1 - 0.11 11.3 6.9 0.15 10.9 6.9 1.0 1 0 0 1 1 1 0 Otopetrin DUF2052 PF09747.9 CDJ48073.1 - 0.15 12.2 17.3 0.22 11.6 17.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ48073.1 - 0.19 11.5 15.6 0.27 11.0 15.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MAM33 PF02330.16 CDJ48073.1 - 0.22 11.5 16.6 0.39 10.6 3.9 2.1 2 0 0 2 2 2 0 Mitochondrial glycoprotein DUF5308 PF17233.2 CDJ48073.1 - 0.32 11.2 13.4 0.74 10.0 2.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5308) AIM3 PF17096.5 CDJ48073.1 - 0.32 12.0 11.4 1.6 9.7 2.3 2.2 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Mlh1_C PF16413.5 CDJ48073.1 - 0.43 9.9 13.4 0.22 10.9 2.8 2.0 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus Orf78 PF06024.12 CDJ48073.1 - 0.5 10.7 11.7 1.3 9.3 2.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) DUF5523 PF17661.1 CDJ48073.1 - 0.52 10.0 17.5 0.71 9.5 4.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DUF2828 PF11443.8 CDJ48073.1 - 0.55 8.3 13.4 0.69 7.9 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF874 PF05917.11 CDJ48073.1 - 0.61 9.1 23.3 0.4 9.7 3.4 2.0 2 0 0 2 2 2 0 Helicobacter pylori protein of unknown function (DUF874) Spt20 PF12090.8 CDJ48073.1 - 0.77 9.3 53.2 0.25 10.9 26.4 2.1 2 0 0 2 2 2 0 Spt20 family PCM1_C PF15717.5 CDJ48073.1 - 0.79 8.3 16.9 1 8.0 16.9 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus PAT1 PF09770.9 CDJ48073.1 - 0.88 7.8 26.9 1.3 7.2 26.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 CDJ48073.1 - 0.97 8.4 15.8 1.3 8.0 15.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Folate_carrier PF01770.18 CDJ48073.1 - 1.2 7.7 11.1 1.2 7.8 0.9 2.0 2 0 0 2 2 2 0 Reduced folate carrier MecA PF05389.12 CDJ48073.1 - 1.5 8.4 14.9 1 8.9 3.1 2.0 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF4820 PF16091.5 CDJ48073.1 - 1.8 7.9 15.0 0.25 10.7 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF4834 PF16118.5 CDJ48073.1 - 1.9 9.5 26.0 3.9 8.5 10.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4518 PF15008.6 CDJ48073.1 - 2.3 7.4 16.0 2 7.5 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) ALMT PF11744.8 CDJ48073.1 - 2.3 6.9 10.4 3.4 6.4 10.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Sld3_N PF18523.1 CDJ48073.1 - 2.4 8.3 8.2 2.2 8.4 0.9 2.1 2 0 0 2 2 2 0 Sld3 N-terminal domain LEA_3 PF03242.13 CDJ48073.1 - 2.7 8.8 5.2 3.3 8.5 0.4 2.1 2 0 0 2 2 2 0 Late embryogenesis abundant protein PRC2_HTH_1 PF18118.1 CDJ48073.1 - 2.8 8.8 12.5 8.8 7.2 2.7 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain FHIPEP PF00771.20 CDJ48073.1 - 3.6 5.9 13.3 2.7 6.4 2.0 2.0 2 0 0 2 2 2 0 FHIPEP family O-antigen_lig PF13425.6 CDJ48073.1 - 4 6.1 7.3 4.7 5.9 7.3 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Thg1C PF14413.6 CDJ48073.1 - 4.2 7.5 17.5 1.2 9.3 4.9 2.1 2 0 0 2 2 2 0 Thg1 C terminal domain TMEM174 PF15029.6 CDJ48073.1 - 4.6 6.9 7.1 4 7.1 0.7 2.1 2 0 0 2 2 2 0 Transmembrane protein 174 SspB PF04386.13 CDJ48073.1 - 4.9 7.0 16.0 0.81 9.6 3.0 2.1 2 0 0 2 2 2 0 Stringent starvation protein B CDC45 PF02724.14 CDJ48073.1 - 5.3 5.2 14.2 8.1 4.6 14.2 1.2 1 0 0 1 1 1 0 CDC45-like protein PH_4 PF15404.6 CDJ48073.1 - 7.6 6.3 12.0 8.3 6.2 2.5 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain tRNA_synt_1c_R2 PF04557.15 CDJ48073.1 - 7.8 7.5 15.1 15 6.6 4.1 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Peroxin-13_N PF04088.13 CDJ48073.1 - 8.1 6.7 11.2 3.2 8.0 1.6 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region ORC_WH_C PF18137.1 CDJ48073.1 - 8.1 6.5 17.2 6.8 6.8 4.0 2.1 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Hid1 PF12722.7 CDJ48073.1 - 9 4.3 14.7 12 3.8 14.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein U1snRNP70_N PF12220.8 CDJ48073.1 - 9.6 6.9 18.6 8.4 7.1 5.0 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4770 PF15994.5 CDJ48073.1 - 9.8 6.4 21.1 4.3 7.5 4.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) NAD_binding_2 PF03446.15 CDJ48076.1 - 7.4e-45 152.9 0.3 1.6e-44 151.9 0.3 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.19 CDJ48076.1 - 1.2e-09 38.0 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain 3HCDH_N PF02737.18 CDJ48076.1 - 0.00014 21.8 0.4 0.00014 21.8 0.4 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CDJ48076.1 - 0.0011 19.6 0.1 0.0011 19.6 0.1 2.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CDJ48076.1 - 0.0059 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CDJ48076.1 - 0.085 13.1 0.0 3 8.1 0.0 2.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 CDJ48076.1 - 0.14 11.5 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF515 PF04415.12 CDJ48076.1 - 0.55 8.6 5.0 0.85 7.9 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CCDC53 PF10152.9 CDJ48077.1 - 3.2 8.2 9.9 4.4 7.7 2.8 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF3306 PF11748.8 CDJ48077.1 - 7 7.5 13.5 6.9 7.6 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) TFIIA PF03153.13 CDJ48078.1 - 0.019 15.0 15.5 0.022 14.8 15.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ48078.1 - 0.26 10.8 9.0 0.31 10.6 9.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.9 CDJ48078.1 - 0.45 8.7 14.4 0.57 8.4 14.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MMR1 PF08505.10 CDJ48078.1 - 0.68 10.2 7.9 0.89 9.8 7.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 CDJ48078.1 - 0.68 8.6 5.0 0.66 8.7 5.0 1.0 1 0 0 1 1 1 0 Presenilin PEPCK_N PF17297.2 CDJ48080.1 - 0.07 12.7 4.6 0.085 12.5 4.6 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain MMR1 PF08505.10 CDJ48080.1 - 0.09 13.1 20.6 0.1 12.9 20.6 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TERB2 PF15101.6 CDJ48080.1 - 0.13 12.3 25.6 0.39 10.8 25.6 1.7 1 1 0 1 1 1 0 Telomere-associated protein TERB2 2HCT PF03390.15 CDJ48080.1 - 0.22 10.1 0.5 0.34 9.5 0.5 1.3 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Stig1 PF04885.13 CDJ48080.1 - 0.23 11.9 12.4 0.3 11.6 12.4 1.1 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 CLN3 PF02487.17 CDJ48080.1 - 0.36 9.8 7.7 0.38 9.8 7.7 1.1 1 0 0 1 1 1 0 CLN3 protein CSG2 PF16965.5 CDJ48080.1 - 0.46 9.4 7.0 0.54 9.1 7.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator O-antigen_lig PF13425.6 CDJ48080.1 - 0.48 9.2 3.0 0.52 9.0 3.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein V_ATPase_I PF01496.19 CDJ48080.1 - 0.51 8.2 11.1 0.47 8.3 11.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 CDJ48080.1 - 0.58 9.9 15.8 0.59 9.9 15.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FliP PF00813.20 CDJ48080.1 - 0.58 10.0 7.5 0.69 9.8 7.5 1.2 1 0 0 1 1 1 0 FliP family DUF913 PF06025.12 CDJ48080.1 - 0.63 8.9 8.5 0.71 8.8 8.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 CDJ48080.1 - 0.64 10.2 11.4 0.95 9.6 11.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4746 PF15928.5 CDJ48080.1 - 0.7 9.3 10.1 0.91 8.9 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SLC12 PF03522.15 CDJ48080.1 - 0.75 8.7 16.7 0.85 8.6 16.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4228 PF14009.6 CDJ48080.1 - 1 9.7 8.9 1.2 9.5 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) BORG_CEP PF14957.6 CDJ48080.1 - 1.2 10.3 13.3 1.5 10.0 13.3 1.1 1 0 0 1 1 1 0 Cdc42 effector Presenilin PF01080.17 CDJ48080.1 - 1.4 7.6 20.7 1.6 7.4 20.7 1.0 1 0 0 1 1 1 0 Presenilin Orf78 PF06024.12 CDJ48080.1 - 1.8 8.9 12.5 48 4.3 12.5 2.1 1 1 0 1 1 1 0 Orf78 (ac78) PXA PF02194.15 CDJ48080.1 - 2.1 8.3 9.6 2.6 8.0 9.6 1.1 1 0 0 1 1 1 0 PXA domain ALMT PF11744.8 CDJ48080.1 - 2.7 6.7 14.3 3 6.6 14.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ48080.1 - 3.3 5.9 29.2 3.5 5.8 29.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.6 CDJ48080.1 - 3.6 5.9 6.8 3.8 5.8 6.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MAJIN PF15077.6 CDJ48080.1 - 4.5 7.0 14.0 4.7 6.9 14.0 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Hid1 PF12722.7 CDJ48080.1 - 4.9 5.2 16.7 5.6 5.0 16.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Paramyxo_ncap PF00973.19 CDJ48080.1 - 5.1 5.9 12.4 5.3 5.8 12.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NEMP PF10225.9 CDJ48080.1 - 5.1 6.7 6.8 5.5 6.6 6.8 1.2 1 0 0 1 1 1 0 NEMP family AUX_IAA PF02309.16 CDJ48080.1 - 6.2 6.6 13.1 7 6.4 13.1 1.1 1 0 0 1 1 1 0 AUX/IAA family XRN_M PF17846.1 CDJ48080.1 - 7.6 5.4 12.3 8.9 5.1 12.3 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Otopetrin PF03189.13 CDJ48080.1 - 8 5.2 8.8 7.7 5.2 8.8 1.1 1 0 0 1 1 1 0 Otopetrin Neur_chan_memb PF02932.16 CDJ48080.1 - 8 6.4 16.0 9.8 6.2 16.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Membralin PF09746.9 CDJ48080.1 - 9.2 5.2 9.2 9.5 5.1 9.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein Hydin_ADK PF17213.3 CDJ48080.1 - 9.4 6.5 14.0 13 6.0 14.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain rve PF00665.26 CDJ48081.1 - 3.3e-11 43.4 0.0 5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ48081.1 - 0.051 13.4 0.8 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 Integrase core domain RT_RNaseH PF17917.1 CDJ48082.1 - 5.9e-26 90.8 0.2 1.8e-25 89.2 0.2 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ48082.1 - 1.9e-25 88.8 0.1 4.5e-25 87.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ48082.1 - 1.5e-15 57.0 1.5 3.3e-15 55.9 1.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ48082.1 - 1.7e-12 47.6 0.1 1e-11 45.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 CDJ48082.1 - 9.4e-08 31.9 0.0 2.1e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ48082.1 - 9.5e-07 29.4 0.0 2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ48082.1 - 9.4e-06 26.1 0.0 2.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 CDJ48082.1 - 0.014 15.6 0.7 0.036 14.3 0.7 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 CDJ48082.1 - 0.027 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 CDJ48082.1 - 0.049 13.9 0.0 0.22 11.9 0.0 2.1 1 0 0 1 1 1 0 Retroviral aspartyl protease DAG_kinase_N PF14513.6 CDJ48082.1 - 0.18 12.0 9.0 0.45 10.7 9.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus CCDC71L PF15374.6 CDJ48082.1 - 0.2 10.9 18.0 0.38 10.0 18.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L EOS1 PF12326.8 CDJ48082.1 - 0.51 10.2 4.9 1.2 9.0 4.9 1.7 1 0 0 1 1 1 0 N-glycosylation protein SLC12 PF03522.15 CDJ48082.1 - 1.3 8.0 16.3 2.1 7.3 16.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 RRN3 PF05327.11 CDJ48082.1 - 3.8 5.9 15.6 22 3.4 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 CDJ48082.1 - 4.8 6.4 48.5 10 5.3 48.5 1.5 1 0 0 1 1 1 0 BUD22 Ras PF00071.22 CDJ48083.1 - 1e-35 122.7 0.1 1.2e-35 122.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ48083.1 - 2.5e-27 95.5 0.1 3e-27 95.2 0.1 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ48083.1 - 4.8e-08 32.6 0.0 6e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ48083.1 - 5.5e-05 23.2 0.0 6.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 CDJ48083.1 - 0.0017 18.2 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 CDJ48083.1 - 0.0092 15.4 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ48083.1 - 0.019 14.9 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase GTP_EFTU PF00009.27 CDJ48083.1 - 0.054 13.0 0.0 0.097 12.2 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDJ48083.1 - 0.063 12.7 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CDJ48083.1 - 0.076 13.3 0.0 0.086 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ48083.1 - 0.098 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 CDJ48083.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.4 1 1 0 1 1 1 0 MCM P-loop domain TniB PF05621.11 CDJ48083.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 CDJ48083.1 - 0.11 12.8 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 CDJ48083.1 - 0.14 12.5 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase DHC_N2 PF08393.13 CDJ48084.1 - 2.5e-87 293.6 6.4 2.5e-87 293.6 6.4 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 CDJ48084.1 - 2.9e-48 164.5 6.2 3e-29 102.0 0.0 4.2 2 1 2 4 4 3 3 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 CDJ48084.1 - 3.6e-46 157.8 0.3 3.9e-44 151.1 0.2 5.4 6 0 0 6 6 6 2 Dynein heavy chain C-terminal domain MT PF12777.7 CDJ48084.1 - 3.8e-40 138.0 10.8 7.6e-40 137.0 10.8 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 CDJ48084.1 - 1.1e-35 123.2 6.5 1.1e-16 61.0 0.0 5.0 5 0 0 5 5 5 3 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ48084.1 - 3.6e-27 94.9 8.8 2.5e-20 72.6 4.3 6.1 6 1 1 7 7 3 2 ATP-binding dynein motor region AAA_lid_11 PF18198.1 CDJ48084.1 - 1e-24 87.2 0.0 6.1e-24 84.7 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ48084.1 - 2.9e-21 75.8 2.9 5.2e-21 74.9 0.0 3.2 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 CDJ48084.1 - 2.1e-13 50.3 0.0 6.5e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_7 PF12775.7 CDJ48084.1 - 1.2e-07 31.4 0.0 0.00028 20.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 CDJ48084.1 - 1.8e-06 28.0 0.0 0.29 11.1 0.0 4.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDJ48084.1 - 2e-06 27.9 0.1 2e-05 24.7 0.0 2.9 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Ribosomal_60s PF00428.19 CDJ48084.1 - 0.00039 20.9 8.4 0.00039 20.9 8.4 14.5 13 1 0 13 13 10 2 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ48084.1 - 0.00053 19.7 6.4 0.00053 19.7 6.4 9.4 10 0 0 10 10 10 2 Spt20 family AAA_16 PF13191.6 CDJ48084.1 - 0.0015 18.9 0.1 0.0015 18.9 0.1 9.2 9 2 0 9 9 6 1 AAA ATPase domain AAA PF00004.29 CDJ48084.1 - 0.55 10.7 2.2 1.7 9.1 0.1 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Not1 PF04054.15 CDJ48085.1 - 1.7e-27 96.3 7.0 2.1e-16 59.8 0.2 2.9 4 0 0 4 4 2 2 CCR4-Not complex component, Not1 BAF1_ABF1 PF04684.13 CDJ48085.1 - 0.00024 20.3 3.9 0.00024 20.3 3.9 2.1 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor O-antigen_lig PF13425.6 CDJ48085.1 - 0.028 13.2 0.2 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 O-antigen ligase like membrane protein FPN1 PF06963.12 CDJ48085.1 - 0.14 10.6 0.1 0.14 10.6 0.1 2.9 3 0 0 3 3 3 0 Ferroportin1 (FPN1) Hid1 PF12722.7 CDJ48085.1 - 0.54 8.3 18.8 1.1 7.4 6.4 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Dala_Dala_lig_N PF01820.21 CDJ48085.1 - 1.2 9.6 5.8 12 6.5 0.1 3.0 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus PTPRCAP PF15713.5 CDJ48085.1 - 1.3 9.3 24.2 0.5 10.6 1.9 3.2 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated FHIPEP PF00771.20 CDJ48085.1 - 4.7 5.6 17.6 0.34 9.3 1.4 3.0 3 0 0 3 3 3 0 FHIPEP family Pet20 PF08692.10 CDJ48085.1 - 5.5 7.7 13.7 7.4 7.3 0.2 3.4 3 0 0 3 3 3 0 Mitochondrial protein Pet20 STAC2_u1 PF16664.5 CDJ48085.1 - 7.3 7.1 14.4 18 5.8 0.0 3.5 3 0 0 3 3 3 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF4834 PF16118.5 CDJ48085.1 - 7.4 7.6 35.4 0.44 11.5 5.2 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) DUF4259 PF14078.6 CDJ48085.1 - 8.3 7.2 12.0 0.18 12.5 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) DUF3819 PF12842.7 CDJ48087.1 - 4.9e-37 127.1 0.9 4.9e-37 127.1 0.9 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) DUF521 PF04412.13 CDJ48087.1 - 7.7 5.1 9.2 0.26 9.9 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF521) Chromo PF00385.24 CDJ48088.1 - 1.7e-07 31.0 0.0 3.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Apt1 PF10351.9 CDJ48089.1 - 0.074 11.9 22.7 0.08 11.8 22.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain MDM10 PF12519.8 CDJ48089.1 - 0.22 10.3 29.1 0.27 10.1 29.1 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SLC12 PF03522.15 CDJ48089.1 - 0.93 8.4 42.5 1.3 8.0 42.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Asp-B-Hydro_N PF05279.11 CDJ48089.1 - 1.4 8.9 32.8 2 8.4 32.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GREB1 PF15782.5 CDJ48089.1 - 1.5 5.8 32.2 1.5 5.8 32.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sec62 PF03839.16 CDJ48089.1 - 1.9 7.9 42.2 3.2 7.2 42.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 PAT1 PF09770.9 CDJ48089.1 - 2.1 6.5 52.6 2.6 6.2 52.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tyrosinase PF00264.20 CDJ48089.1 - 4.4 7.5 17.0 5 7.3 17.0 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase Pkinase_fungal PF17667.1 CDJ48089.1 - 6.1 5.5 20.2 7 5.3 20.2 1.3 1 0 0 1 1 1 0 Fungal protein kinase CRT10 PF08728.10 CDJ48089.1 - 8.7 4.4 18.9 9.1 4.3 18.9 1.0 1 0 0 1 1 1 0 CRT10 Ndc1_Nup PF09531.10 CDJ48089.1 - 9.5 4.8 33.7 10 4.7 33.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF966 PF06136.13 CDJ48089.1 - 9.7 5.8 32.0 12 5.5 32.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RAP1 PF07218.11 CDJ48091.1 - 0.69 8.1 17.5 0.91 7.7 17.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sin_N PF04801.13 CDJ48091.1 - 1.4 8.0 44.8 0.083 12.1 19.4 2.4 2 0 0 2 2 2 0 Sin-like protein conserved region O-antigen_lig PF13425.6 CDJ48091.1 - 1.6 7.5 5.6 8.8 5.0 0.0 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein PAP1 PF08601.10 CDJ48091.1 - 2.5 7.7 57.1 0.55 9.9 39.5 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 DUF4647 PF15504.6 CDJ48091.1 - 5.7 5.9 36.4 6.2 5.8 7.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) DUF4834 PF16118.5 CDJ48092.1 - 0.00036 21.4 5.7 0.0027 18.6 0.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) DUF1980 PF09323.10 CDJ48092.1 - 0.0059 16.5 0.2 0.0059 16.5 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1980) DUF4820 PF16091.5 CDJ48092.1 - 0.0061 15.9 0.7 0.0061 15.9 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4820) Pex14_N PF04695.13 CDJ48092.1 - 0.0078 16.9 4.0 0.0078 16.9 4.0 2.1 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region FHIPEP PF00771.20 CDJ48092.1 - 0.0086 14.6 4.9 0.011 14.3 4.9 1.2 1 0 0 1 1 1 1 FHIPEP family RskA PF10099.9 CDJ48092.1 - 0.0095 16.2 5.5 0.0095 16.2 5.5 2.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ48092.1 - 0.056 12.2 8.0 0.073 11.8 8.0 1.2 1 0 0 1 1 1 0 Presenilin Folate_carrier PF01770.18 CDJ48092.1 - 0.061 12.1 0.8 0.092 11.5 0.8 1.3 1 0 0 1 1 1 0 Reduced folate carrier ABC2_membrane_2 PF12679.7 CDJ48092.1 - 0.091 12.0 0.7 0.21 10.8 0.7 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein ArsP_2 PF11449.8 CDJ48092.1 - 0.11 11.7 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter PGA_cap PF09587.10 CDJ48092.1 - 0.19 11.2 2.9 0.21 11.0 2.9 1.1 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap CSG2 PF16965.5 CDJ48092.1 - 0.2 10.6 2.5 0.064 12.2 0.2 1.3 2 0 0 2 2 2 0 Ceramide synthase regulator MMPL PF03176.15 CDJ48092.1 - 0.3 10.0 5.1 0.36 9.7 5.1 1.2 1 0 0 1 1 1 0 MMPL family DUF808 PF05661.12 CDJ48092.1 - 0.44 9.6 2.1 0.19 10.7 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF808) DUF1180 PF06679.12 CDJ48092.1 - 0.44 10.9 6.4 0.041 14.3 2.4 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF1180) Zip PF02535.22 CDJ48092.1 - 0.49 9.6 2.6 0.43 9.7 2.1 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 CDJ48092.1 - 0.57 9.0 5.9 0.038 12.9 1.3 1.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) OapA_N PF08525.11 CDJ48092.1 - 0.6 10.1 5.5 1 9.4 5.5 1.3 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif R_equi_Vir PF05526.11 CDJ48092.1 - 0.85 9.5 5.3 0.23 11.3 1.8 1.7 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein Cyclin_N2 PF16500.5 CDJ48092.1 - 1.1 10.0 12.9 0.89 10.3 8.0 2.1 2 0 0 2 2 2 0 N-terminal region of cyclin_N FYDLN_acid PF09538.10 CDJ48092.1 - 1.2 9.8 9.5 0.13 13.0 4.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) AAA_23 PF13476.6 CDJ48092.1 - 1.5 9.3 15.6 1.1 9.7 10.9 2.0 2 0 0 2 2 2 0 AAA domain DUF2722 PF10846.8 CDJ48092.1 - 1.6 7.6 30.9 0.083 11.8 17.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ48092.1 - 2.7 7.6 41.4 2.1 7.9 26.2 2.1 2 0 0 2 2 2 0 Spt20 family DUF4407 PF14362.6 CDJ48092.1 - 3.4 7.0 15.8 0.07 12.5 7.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PP31 PF05311.11 CDJ48092.1 - 3.6 7.0 10.3 0.25 10.8 3.0 1.9 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Kei1 PF08552.11 CDJ48092.1 - 3.7 7.4 5.0 0.82 9.5 1.6 1.7 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 CTU2 PF10288.9 CDJ48092.1 - 4.9 7.4 11.0 0.6 10.4 4.9 2.0 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 ANAPC_CDC26 PF10471.9 CDJ48092.1 - 5.2 8.0 35.5 0.59 11.0 18.6 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF2946 PF11162.8 CDJ48092.1 - 5.4 7.7 7.3 0.81 10.4 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Ctr PF04145.15 CDJ48092.1 - 7.5 7.2 10.6 25 5.5 10.6 1.8 1 1 0 1 1 1 0 Ctr copper transporter family RPA43_OB PF17875.1 CDJ48092.1 - 9.4 6.9 12.7 0.5 11.0 6.9 1.8 1 1 1 2 2 2 0 RPA43 OB domain in RNA Pol I CD20 PF04103.15 CDJ48093.1 - 0.35 10.9 0.0 0.35 10.9 0.0 2.5 2 1 0 2 2 2 0 CD20-like family RE_TdeIII PF09520.10 CDJ48093.1 - 1.8 8.2 12.7 0.029 14.1 2.1 2.0 2 0 0 2 2 2 0 Type II restriction endonuclease, TdeIII Hamartin PF04388.12 CDJ48093.1 - 7.9 5.0 38.9 9 4.8 38.9 1.0 1 0 0 1 1 1 0 Hamartin protein Actin PF00022.19 CDJ48094.1 - 5e-43 147.3 0.0 1e-41 142.9 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CDJ48094.1 - 0.024 13.5 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein PI3_PI4_kinase PF00454.27 CDJ48096.1 - 4.8e-18 65.9 0.0 3.8e-15 56.4 0.0 2.9 2 1 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CDJ48096.1 - 1.3e-09 37.7 0.0 3.8e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 FATC domain DUF2722 PF10846.8 CDJ48096.1 - 0.001 18.1 3.7 0.001 18.1 3.7 23.2 20 3 2 22 22 22 10 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ48096.1 - 0.0024 18.2 5.4 0.0024 18.2 5.4 46.2 12 8 21 35 35 35 6 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ48096.1 - 0.0025 17.9 19.2 0.0025 17.9 19.2 23.2 11 5 7 18 18 18 5 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ48097.1 - 0.00097 19.2 0.1 0.00097 19.2 0.1 5.2 1 1 4 5 5 5 1 SPX domain DUF2722 PF10846.8 CDJ48098.1 - 0.0026 16.8 17.6 0.003 16.6 17.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) FliD_N PF02465.18 CDJ48098.1 - 0.0035 18.0 10.6 0.0052 17.5 10.6 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus Spt20 PF12090.8 CDJ48098.1 - 0.0055 16.3 20.8 0.0061 16.2 20.8 1.1 1 0 0 1 1 1 1 Spt20 family Gtr1_RagA PF04670.12 CDJ48098.1 - 0.0058 16.0 3.1 0.0063 15.9 3.1 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PDZ_4 PF17816.1 CDJ48098.1 - 0.019 15.3 0.9 0.05 14.0 0.0 1.8 1 1 1 2 2 2 0 PDZ domain Kei1 PF08552.11 CDJ48098.1 - 0.024 14.5 1.5 0.024 14.5 1.5 1.9 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2428 PF10350.9 CDJ48098.1 - 0.03 13.6 4.3 0.028 13.7 4.3 1.0 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Lin-8 PF03353.15 CDJ48098.1 - 0.043 13.4 10.1 0.047 13.3 10.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Methyltransf_12 PF08242.12 CDJ48098.1 - 0.063 14.0 1.3 0.1 13.4 1.3 1.3 1 0 0 1 1 1 0 Methyltransferase domain Med15 PF09606.10 CDJ48098.1 - 0.073 11.7 15.4 0.063 12.0 15.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ48098.1 - 0.098 12.6 19.9 0.11 12.4 19.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ48098.1 - 0.1 12.6 4.0 0.1 12.6 4.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_60s PF00428.19 CDJ48098.1 - 0.13 12.9 7.0 0.089 13.4 4.8 1.8 1 1 1 2 2 2 0 60s Acidic ribosomal protein DUF775 PF05603.12 CDJ48098.1 - 0.27 10.7 9.9 0.34 10.4 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) CPSF100_C PF13299.6 CDJ48098.1 - 0.33 11.1 6.0 0.4 10.8 6.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal EPL1 PF10513.9 CDJ48098.1 - 0.34 11.3 9.0 0.41 11.0 9.0 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like FHIPEP PF00771.20 CDJ48098.1 - 0.46 8.9 6.0 0.47 8.9 6.0 1.0 1 0 0 1 1 1 0 FHIPEP family Sec62 PF03839.16 CDJ48098.1 - 0.76 9.2 5.3 0.77 9.2 5.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 CDJ48098.1 - 0.88 8.3 9.3 0.91 8.2 9.3 1.1 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 CDJ48098.1 - 1.7 7.0 9.6 1.5 7.2 9.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PcfK PF14058.6 CDJ48098.1 - 2.3 8.5 14.5 2 8.7 13.0 1.6 2 0 0 2 2 2 0 PcfK-like protein DUF3270 PF11674.8 CDJ48098.1 - 4.4 7.6 8.1 7 6.9 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) GREB1 PF15782.5 CDJ48098.1 - 4.7 4.2 11.1 4.9 4.1 11.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Orf78 PF06024.12 CDJ48098.1 - 7.5 6.9 8.7 4.7 7.6 6.9 1.6 1 1 1 2 2 2 0 Orf78 (ac78) PPL5 PF18168.1 CDJ48099.1 - 0.0008 18.8 13.4 0.0011 18.4 13.4 1.2 1 0 0 1 1 1 1 Prim-pol family 5 CCSAP PF15748.5 CDJ48099.1 - 0.0037 17.5 33.2 0.0044 17.2 33.2 1.1 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated Apt1 PF10351.9 CDJ48099.1 - 0.0088 14.9 13.9 0.0088 14.9 13.9 1.0 1 0 0 1 1 1 1 Golgi-body localisation protein domain Dsh_C PF12316.8 CDJ48099.1 - 0.01 16.3 21.8 0.011 16.1 21.8 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Draxin PF15550.6 CDJ48099.1 - 0.039 13.8 20.5 0.046 13.6 20.5 1.0 1 0 0 1 1 1 0 Draxin CDC45 PF02724.14 CDJ48099.1 - 0.065 11.5 26.9 0.072 11.4 26.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ48099.1 - 0.1 11.3 39.7 0.12 11.1 39.7 1.1 1 0 0 1 1 1 0 Presenilin FRQ PF09421.10 CDJ48099.1 - 0.14 10.1 19.2 0.18 9.8 19.2 1.0 1 0 0 1 1 1 0 Frequency clock protein DUF572 PF04502.13 CDJ48099.1 - 0.28 10.8 24.4 0.31 10.6 24.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) AAA_11 PF13086.6 CDJ48099.1 - 0.32 10.8 26.4 0.36 10.6 26.4 1.1 1 0 0 1 1 1 0 AAA domain Dicty_REP PF05086.12 CDJ48099.1 - 0.37 8.7 17.2 0.39 8.6 17.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RR_TM4-6 PF06459.12 CDJ48099.1 - 0.44 10.3 33.5 0.58 9.9 33.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ48099.1 - 0.45 9.3 25.0 0.51 9.1 25.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4045 PF13254.6 CDJ48099.1 - 0.5 9.9 31.3 0.61 9.7 31.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) LptF_LptG PF03739.14 CDJ48099.1 - 0.54 9.0 8.6 0.71 8.7 8.6 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG LAP1C PF05609.12 CDJ48099.1 - 0.55 9.3 30.6 0.63 9.1 30.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SLC12 PF03522.15 CDJ48099.1 - 0.58 9.1 33.9 0.69 8.9 33.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF1387 PF07139.11 CDJ48099.1 - 0.72 9.5 28.2 1.1 9.0 28.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SRP-alpha_N PF04086.13 CDJ48099.1 - 0.86 9.5 29.1 1.1 9.1 29.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PAT1 PF09770.9 CDJ48099.1 - 1 7.6 54.2 1.2 7.4 54.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cellulose_synt PF03552.14 CDJ48099.1 - 1.2 7.5 9.4 1.5 7.3 9.4 1.2 1 0 0 1 1 1 0 Cellulose synthase DUF5427 PF10310.9 CDJ48099.1 - 1.3 7.9 32.9 2.1 7.2 32.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) NARP1 PF12569.8 CDJ48099.1 - 1.5 7.7 29.2 2.4 7.0 29.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Dapper PF15268.6 CDJ48099.1 - 1.6 7.5 34.8 1.8 7.3 34.8 1.0 1 0 0 1 1 1 0 Dapper Lin-8 PF03353.15 CDJ48099.1 - 1.7 8.1 37.2 2.1 7.8 37.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Neur_chan_memb PF02932.16 CDJ48099.1 - 2.3 8.2 26.6 3.1 7.8 26.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Exonuc_VII_L PF02601.15 CDJ48099.1 - 2.7 7.5 35.5 3.6 7.1 35.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AF-4 PF05110.13 CDJ48099.1 - 2.9 5.9 38.0 3.4 5.6 38.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2052 PF09747.9 CDJ48099.1 - 2.9 8.0 33.1 4.1 7.5 33.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDK5_activator PF03261.15 CDJ48099.1 - 4.6 6.7 23.6 5.1 6.5 23.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein GREB1 PF15782.5 CDJ48099.1 - 4.7 4.2 35.2 5.5 4.0 35.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PNISR PF15996.5 CDJ48099.1 - 4.8 7.4 41.0 5.8 7.1 41.0 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Peptidase_S64 PF08192.11 CDJ48099.1 - 4.9 5.5 25.8 5.8 5.3 25.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Membralin PF09746.9 CDJ48099.1 - 5.9 5.8 20.8 6.9 5.6 20.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein Calici_coat_C PF08435.11 CDJ48099.1 - 5.9 6.3 19.7 7.6 6.0 19.7 1.1 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal RIFIN PF02009.16 CDJ48099.1 - 6 6.7 24.2 11 5.8 24.2 1.4 1 0 0 1 1 1 0 Rifin Caldesmon PF02029.15 CDJ48099.1 - 6.1 5.5 35.9 7.2 5.2 35.9 1.0 1 0 0 1 1 1 0 Caldesmon DUF4551 PF15087.6 CDJ48099.1 - 6.5 5.5 24.7 7.7 5.2 24.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GAGA_bind PF06217.12 CDJ48099.1 - 6.8 6.9 26.6 8.5 6.6 26.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Miga PF10265.9 CDJ48099.1 - 7.3 5.4 20.2 8.8 5.2 20.2 1.0 1 0 0 1 1 1 0 Mitoguardin DUF740 PF05340.12 CDJ48099.1 - 7.4 5.2 15.8 9.3 4.9 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) SOG2 PF10428.9 CDJ48099.1 - 7.6 5.6 27.2 9.1 5.4 27.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein FAM60A PF15396.6 CDJ48099.1 - 9.4 6.2 30.5 12 5.8 30.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A GTP_EFTU PF00009.27 CDJ48100.1 - 0.0011 18.6 0.0 0.0011 18.6 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Serinc PF03348.15 CDJ48103.1 - 0.51 9.2 8.3 0.042 12.8 3.0 1.8 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF2052 PF09747.9 CDJ48103.1 - 0.69 10.0 19.7 16 5.6 17.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CaKB PF03185.15 CDJ48104.1 - 0.00098 18.8 0.3 0.0015 18.2 0.3 1.2 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit Semialdhyde_dhC PF02774.18 CDJ48104.1 - 0.025 14.7 0.2 0.042 13.9 0.2 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain DUF4611 PF15387.6 CDJ48104.1 - 0.34 11.1 7.7 0.11 12.7 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF2052 PF09747.9 CDJ48104.1 - 8.4 6.5 13.1 1.4 9.0 8.6 1.8 1 1 1 2 2 2 0 Coiled-coil domain containing protein (DUF2052) KfrA_N PF11740.8 CDJ48105.1 - 0.049 14.3 13.2 0.057 14.1 13.2 1.0 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term PhetRS_B1 PF18262.1 CDJ48105.1 - 0.066 13.4 0.2 0.081 13.2 0.2 1.1 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain PTS_IIB PF02302.17 CDJ48105.1 - 0.14 12.8 0.2 0.2 12.3 0.2 1.2 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit AAA_26 PF13500.6 CDJ48105.1 - 0.21 11.4 1.6 0.25 11.2 1.6 1.1 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 CDJ48105.1 - 1.9 7.8 8.3 2.1 7.6 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Es2 PF09751.9 CDJ48106.1 - 0.12 12.0 9.0 0.19 11.4 9.0 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 DUF3984 PF13136.6 CDJ48106.1 - 0.18 11.2 14.7 4.5 6.6 13.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) SARAF PF06682.12 CDJ48106.1 - 0.21 11.2 12.1 0.33 10.6 12.1 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis RR_TM4-6 PF06459.12 CDJ48106.1 - 0.21 11.4 7.7 0.34 10.7 7.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Velvet PF11754.8 CDJ48106.1 - 0.29 11.0 9.4 0.49 10.3 9.4 1.3 1 0 0 1 1 1 0 Velvet factor SelP_N PF04592.14 CDJ48106.1 - 0.29 10.5 25.9 0.019 14.4 18.1 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Presenilin PF01080.17 CDJ48106.1 - 0.41 9.3 12.5 0.61 8.8 12.5 1.1 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 CDJ48106.1 - 0.77 9.7 2.2 2.4 8.0 0.2 2.0 2 0 0 2 2 2 0 N-glycosylation protein DUF2722 PF10846.8 CDJ48106.1 - 0.95 8.3 31.9 0.33 9.9 12.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SLC12 PF03522.15 CDJ48106.1 - 1.6 7.6 11.2 2.3 7.2 11.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DcuA_DcuB PF03605.14 CDJ48106.1 - 1.7 7.4 6.7 1.1 8.1 0.1 2.1 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter MDM10 PF12519.8 CDJ48106.1 - 2.7 6.8 7.0 3.9 6.2 7.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4834 PF16118.5 CDJ48106.1 - 3.4 8.7 16.6 2.4 9.2 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2828 PF11443.8 CDJ48106.1 - 3.4 5.6 11.3 4.7 5.2 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PAT1 PF09770.9 CDJ48106.1 - 4 5.6 23.7 5.5 5.1 23.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.7 CDJ48106.1 - 6.1 4.8 8.3 8.3 4.4 8.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 CDJ48106.1 - 9 5.0 6.9 14 4.3 6.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter GRAM PF02893.20 CDJ48108.1 - 1.2e-13 50.9 1.2 2.9e-13 49.7 1.2 1.7 1 0 0 1 1 1 1 GRAM domain DUF2722 PF10846.8 CDJ48108.1 - 0.00058 18.9 1.6 0.00058 18.9 1.6 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) Peptidase_S49_N PF08496.10 CDJ48108.1 - 2.2 8.4 12.0 13 5.8 0.1 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Connexin PF00029.19 CDJ48108.1 - 7.1 6.3 14.7 3.4 7.4 2.4 2.5 2 1 0 2 2 2 0 Connexin HMW1C_N PF18071.1 CDJ48109.1 - 0.0054 16.5 0.0 0.007 16.2 0.0 1.1 1 0 0 1 1 1 1 HMW1C N-terminal Syntaxin PF00804.25 CDJ48109.1 - 0.088 12.5 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Syntaxin K_channel_TID PF07941.11 CDJ48109.1 - 3.3 8.2 15.7 0.45 11.0 11.2 1.9 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Fcf2 PF08698.11 CDJ48110.1 - 3.4e-07 30.6 0.8 1.2e-06 28.8 0.8 2.1 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing MMR_HSR1 PF01926.23 CDJ48111.1 - 1.7e-09 37.8 0.0 2.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 CDJ48111.1 - 0.0011 18.0 0.4 0.0017 17.4 0.4 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 CDJ48111.1 - 0.0013 18.3 0.0 0.0036 16.9 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 CDJ48111.1 - 0.0038 17.4 0.0 0.0056 16.9 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CDJ48111.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CDJ48111.1 - 0.25 11.4 0.0 1.8 8.6 0.0 1.9 2 0 0 2 2 2 0 Dynamin family ArsP_2 PF11449.8 CDJ48112.1 - 0.19 10.9 3.4 0.21 10.8 3.4 1.0 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter Peptidase_S15 PF02129.18 CDJ48112.1 - 0.23 11.0 16.3 0.25 10.9 16.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Glt_symporter PF03616.14 CDJ48112.1 - 0.5 9.0 6.4 0.64 8.6 6.4 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Connexin PF00029.19 CDJ48112.1 - 0.55 9.9 7.7 0.47 10.2 7.7 1.1 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 CDJ48112.1 - 1.5 7.1 3.9 1.4 7.3 3.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF-3_zeta PF05091.12 CDJ48112.1 - 1.7 7.5 20.5 1.7 7.6 20.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.13 CDJ48112.1 - 2 8.2 12.0 1.8 8.3 12.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain EOS1 PF12326.8 CDJ48112.1 - 2 8.3 6.7 1.9 8.4 6.7 1.1 1 0 0 1 1 1 0 N-glycosylation protein Sec62 PF03839.16 CDJ48112.1 - 2.1 7.8 7.9 1.8 8.0 7.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Activator_LAG-3 PF11498.8 CDJ48112.1 - 2.2 7.2 46.7 2.6 6.9 46.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF1980 PF09323.10 CDJ48112.1 - 2.3 8.1 9.9 2.2 8.1 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Pannexin_like PF12534.8 CDJ48112.1 - 2.5 7.1 10.1 2.9 6.9 10.1 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 ALMT PF11744.8 CDJ48112.1 - 3.3 6.4 8.2 3 6.6 8.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 CDJ48112.1 - 4.7 5.0 13.7 4.4 5.1 13.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 CDJ48112.1 - 5.3 6.8 14.2 5.6 6.7 14.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CLN3 PF02487.17 CDJ48112.1 - 6.7 5.6 9.7 6.4 5.7 9.7 1.1 1 0 0 1 1 1 0 CLN3 protein DDHD PF02862.17 CDJ48112.1 - 6.9 6.8 15.2 7.4 6.7 15.2 1.1 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 CDJ48112.1 - 6.9 6.7 10.8 7 6.6 10.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 CDJ48112.1 - 7.8 5.3 9.9 7.7 5.3 9.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) PCI PF01399.27 CDJ48114.1 - 4.7e-12 46.3 0.2 1.1e-11 45.1 0.2 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 CDJ48114.1 - 0.08 13.1 1.6 0.62 10.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN1_RPN2_N PF17781.1 CDJ48116.1 - 1.1e-113 379.7 1.7 1.8e-113 379.0 1.7 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CDJ48116.1 - 8.3e-27 93.0 0.1 1.7e-26 92.0 0.1 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CDJ48116.1 - 5.3e-11 42.4 36.9 0.00027 21.2 0.2 8.5 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CDJ48116.1 - 0.0089 16.4 3.6 0.13 12.7 0.1 4.1 3 2 1 4 4 4 1 HEAT repeats SHMT PF00464.19 CDJ48118.1 - 8.9e-164 544.8 0.0 1.3e-163 544.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase PI3_PI4_kinase PF00454.27 CDJ48118.1 - 7.7e-30 104.5 0.0 1.2e-29 103.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase zf-C2H2_12 PF18658.1 CDJ48118.1 - 0.0043 16.6 0.5 0.35 10.5 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger C2H2-type RskA PF10099.9 CDJ48119.1 - 0.46 10.7 6.1 0.048 14.0 0.8 2.1 2 1 0 2 2 2 0 Anti-sigma-K factor rskA zf-rbx1 PF12678.7 CDJ48121.1 - 1.1e-06 28.8 3.9 6.2e-06 26.4 3.9 2.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CDJ48121.1 - 2e-06 27.7 1.3 6.1e-06 26.2 1.3 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CDJ48121.1 - 3e-06 27.4 2.1 3e-06 27.4 2.1 1.8 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 CDJ48121.1 - 6.2e-06 26.3 2.3 1.3e-05 25.2 2.3 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.6 CDJ48121.1 - 3.5e-05 23.7 1.6 3.5e-05 23.7 1.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 CDJ48121.1 - 3.9e-05 23.3 5.2 6.9e-05 22.5 5.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDJ48121.1 - 0.00032 20.5 1.9 0.00032 20.5 1.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 CDJ48121.1 - 0.00039 20.6 2.5 0.0022 18.2 0.6 2.5 2 0 0 2 2 2 1 zinc-ribbon zf-C3HC4_2 PF13923.6 CDJ48121.1 - 0.0018 18.1 1.7 0.0018 18.1 1.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 CDJ48121.1 - 0.034 14.4 1.1 0.034 14.4 1.1 2.2 2 0 0 2 2 1 0 PHD-like zinc-binding domain PHD PF00628.29 CDJ48121.1 - 0.33 10.9 9.2 0.59 10.1 3.3 2.6 2 0 0 2 2 2 0 PHD-finger DUF5321 PF17254.2 CDJ48121.1 - 1.3 8.4 0.0 1.3 8.4 0.0 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5321) zf-HC5HC2H_2 PF13832.6 CDJ48121.1 - 7.1 6.8 8.0 0.15 12.2 0.8 1.9 2 0 0 2 2 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.6 CDJ48121.1 - 7.9 6.5 8.6 2.1 8.4 1.4 2.6 2 0 0 2 2 2 0 zinc-RING finger domain Zn-ribbon_8 PF09723.10 CDJ48121.1 - 8 6.7 6.1 2.1 8.5 0.7 2.5 2 0 0 2 2 2 0 Zinc ribbon domain FUSC PF04632.12 CDJ48122.1 - 0.54 8.7 31.8 0.63 8.5 31.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1387 PF07139.11 CDJ48122.1 - 1.5 8.5 22.1 2 8.1 22.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Auxin_canalis PF05703.11 CDJ48122.1 - 3.1 7.6 29.0 4.3 7.2 29.0 1.2 1 0 0 1 1 1 0 Auxin canalisation Caldesmon PF02029.15 CDJ48122.1 - 3.3 6.4 25.7 3.5 6.3 25.7 1.1 1 0 0 1 1 1 0 Caldesmon Gti1_Pac2 PF09729.9 CDJ48122.1 - 4.7 7.3 18.5 6.4 6.8 18.5 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Asp-B-Hydro_N PF05279.11 CDJ48122.1 - 5.2 7.1 17.1 6.5 6.7 17.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Lin-8 PF03353.15 CDJ48122.1 - 7.4 6.0 27.7 12 5.4 27.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CCSAP PF15748.5 CDJ48122.1 - 10 6.2 27.1 11 6.1 27.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SR-25 PF10500.9 CDJ48123.1 - 0.001 18.7 10.5 0.0014 18.3 10.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ48123.1 - 0.0051 15.8 20.7 0.0051 15.8 20.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) AF-4 PF05110.13 CDJ48123.1 - 0.0071 14.5 19.7 0.0082 14.3 19.7 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein CNDH2_C PF16858.5 CDJ48123.1 - 0.0082 16.0 8.9 0.009 15.9 8.9 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term TCP PF03634.13 CDJ48123.1 - 0.06 13.9 12.4 0.083 13.5 12.4 1.2 1 0 0 1 1 1 0 TCP family transcription factor Presenilin PF01080.17 CDJ48123.1 - 0.082 11.7 13.4 0.087 11.6 13.4 1.2 1 0 0 1 1 1 0 Presenilin HSP70 PF00012.20 CDJ48123.1 - 0.13 10.4 7.9 0.13 10.4 7.9 1.0 1 0 0 1 1 1 0 Hsp70 protein eIF-3_zeta PF05091.12 CDJ48123.1 - 0.2 10.6 11.9 0.22 10.5 11.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ48123.1 - 0.25 11.3 35.6 0.33 10.9 35.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ48123.1 - 0.31 9.7 27.7 0.37 9.4 27.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MecA PF05389.12 CDJ48123.1 - 0.33 10.6 6.3 0.39 10.3 6.3 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Neur_chan_memb PF02932.16 CDJ48123.1 - 0.37 10.8 9.8 0.42 10.6 9.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ48123.1 - 0.41 10.6 19.7 0.43 10.5 19.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MMR1 PF08505.10 CDJ48123.1 - 0.51 10.6 17.5 0.65 10.2 17.5 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PA26 PF04636.13 CDJ48123.1 - 0.59 9.0 12.1 0.66 8.8 12.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RIFIN PF02009.16 CDJ48123.1 - 0.75 9.6 11.1 0.95 9.3 11.1 1.2 1 0 0 1 1 1 0 Rifin V_ATPase_I PF01496.19 CDJ48123.1 - 0.76 7.6 7.7 0.78 7.6 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Corona_nucleoca PF00937.18 CDJ48123.1 - 0.8 8.7 17.3 0.95 8.4 17.3 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CCSAP PF15748.5 CDJ48123.1 - 0.91 9.6 20.1 1.1 9.4 20.1 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4407 PF14362.6 CDJ48123.1 - 1.2 8.4 17.0 1.4 8.2 17.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF572 PF04502.13 CDJ48123.1 - 1.2 8.7 15.5 1.4 8.4 15.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nop53 PF07767.11 CDJ48123.1 - 1.2 8.4 17.8 1.4 8.2 17.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Draxin PF15550.6 CDJ48123.1 - 1.2 8.9 10.1 1.5 8.6 10.1 1.1 1 0 0 1 1 1 0 Draxin RR_TM4-6 PF06459.12 CDJ48123.1 - 1.3 8.8 12.2 1.6 8.5 12.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4518 PF15008.6 CDJ48123.1 - 1.4 8.0 10.1 1.9 7.6 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) CLN3 PF02487.17 CDJ48123.1 - 1.6 7.7 5.7 1.6 7.7 5.7 1.2 1 0 0 1 1 1 0 CLN3 protein Velvet PF11754.8 CDJ48123.1 - 1.6 8.6 15.7 1.9 8.3 15.7 1.2 1 0 0 1 1 1 0 Velvet factor Rgp1 PF08737.10 CDJ48123.1 - 1.9 7.6 12.1 2.1 7.4 12.1 1.0 1 0 0 1 1 1 0 Rgp1 XRN_M PF17846.1 CDJ48123.1 - 2.2 7.1 7.8 2.2 7.1 7.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Endostatin PF06482.11 CDJ48123.1 - 2.4 7.6 13.2 2.7 7.4 13.2 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SOBP PF15279.6 CDJ48123.1 - 3.8 8.0 18.5 4.5 7.8 18.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein EOS1 PF12326.8 CDJ48123.1 - 4.4 7.2 5.8 6.5 6.6 5.8 1.3 1 0 0 1 1 1 0 N-glycosylation protein SLC12 PF03522.15 CDJ48123.1 - 4.4 6.2 11.5 5 6.0 11.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4045 PF13254.6 CDJ48123.1 - 4.8 6.7 23.0 5.5 6.5 23.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) ALMT PF11744.8 CDJ48123.1 - 5.5 5.7 9.3 6.1 5.6 9.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RLL PF10036.9 CDJ48123.1 - 5.9 6.7 19.6 4.9 6.9 18.7 1.3 1 1 0 1 1 1 0 RNA transcription, translation and transport factor protein Zip PF02535.22 CDJ48123.1 - 6.9 5.8 9.8 8.8 5.4 9.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S64 PF08192.11 CDJ48123.1 - 7 5.0 11.5 8.5 4.7 11.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF1387 PF07139.11 CDJ48123.1 - 7.6 6.2 16.5 10 5.7 16.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) XRCC4 PF06632.12 CDJ48123.1 - 8.1 5.2 14.4 11 4.8 14.4 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 ABC2_membrane_2 PF12679.7 CDJ48123.1 - 8.2 5.6 9.4 12 5.1 9.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Apt1 PF10351.9 CDJ48123.1 - 8.5 5.1 12.5 10 4.8 12.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spt20 PF12090.8 CDJ48124.1 - 0.021 14.5 16.3 0.023 14.3 16.3 1.0 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ48124.1 - 0.14 11.2 8.4 0.14 11.2 8.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Lin-8 PF03353.15 CDJ48124.1 - 0.3 10.6 5.2 0.35 10.4 5.2 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2722 PF10846.8 CDJ48124.1 - 0.33 9.9 12.8 0.33 9.8 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ48124.1 - 0.34 11.9 2.8 0.37 11.8 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FSA_C PF10479.9 CDJ48124.1 - 0.38 8.8 4.4 0.37 8.9 4.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MAS20 PF02064.15 CDJ48124.1 - 0.7 10.0 8.2 0.92 9.6 7.9 1.3 1 1 0 1 1 1 0 MAS20 protein import receptor DUF702 PF05142.12 CDJ48124.1 - 0.72 10.3 7.7 0.84 10.1 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) TFIIA PF03153.13 CDJ48124.1 - 0.91 9.5 17.6 1 9.3 17.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRR18 PF15671.5 CDJ48124.1 - 2.4 8.0 13.2 2.6 7.9 13.2 1.0 1 0 0 1 1 1 0 Proline-rich protein family 18 Herpes_UL74 PF07982.12 CDJ48124.1 - 3.3 6.6 4.8 3.7 6.4 4.8 1.0 1 0 0 1 1 1 0 Herpes UL74 glycoproteins DUF3138 PF11336.8 CDJ48124.1 - 8.9 4.8 14.8 9.4 4.7 14.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Presenilin PF01080.17 CDJ48124.1 - 9 4.9 7.2 8.9 5.0 7.2 1.0 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 CDJ48125.1 - 6.4e-05 23.3 10.4 6.4e-05 23.3 10.4 4.6 1 1 2 3 3 3 1 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ48125.1 - 0.06 13.8 0.0 0.81 10.2 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) PPP4R2 PF09184.11 CDJ48125.1 - 0.32 10.5 35.6 0.49 9.9 4.8 2.4 2 0 0 2 2 2 0 PPP4R2 UCR_TM PF02921.14 CDJ48125.1 - 2.8 8.5 0.0 2.8 8.5 0.0 3.5 4 0 0 4 4 4 0 Ubiquinol cytochrome reductase transmembrane region DUF1345 PF07077.11 CDJ48126.1 - 0.013 15.2 1.8 0.018 14.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DUF677 PF05055.12 CDJ48126.1 - 0.021 13.8 4.0 0.023 13.6 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF4667 PF15700.5 CDJ48126.1 - 0.053 13.6 14.1 0.073 13.2 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ48126.1 - 0.063 13.3 36.3 0.075 13.0 36.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ48126.1 - 0.33 11.1 16.5 0.42 10.7 16.5 1.1 1 0 0 1 1 1 0 DDHD domain MSP1_C PF07462.11 CDJ48126.1 - 0.35 9.5 9.9 0.42 9.3 9.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SID-1_RNA_chan PF13965.6 CDJ48126.1 - 0.46 8.8 5.7 0.52 8.7 5.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Med3 PF11593.8 CDJ48126.1 - 0.71 9.0 36.9 0.98 8.5 36.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1387 PF07139.11 CDJ48126.1 - 0.72 9.5 20.4 0.8 9.4 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SRP-alpha_N PF04086.13 CDJ48126.1 - 0.8 9.6 22.2 0.96 9.3 22.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Serinc PF03348.15 CDJ48126.1 - 0.94 8.3 10.0 1.1 8.1 10.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) GNAT_acetyltr_2 PF13718.6 CDJ48126.1 - 1.2 8.5 13.8 0.047 13.1 6.8 1.9 1 1 1 2 2 2 0 GNAT acetyltransferase 2 Suf PF05843.14 CDJ48126.1 - 1.3 9.0 21.2 1.4 8.8 21.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FHIPEP PF00771.20 CDJ48126.1 - 1.4 7.3 9.4 1.7 7.0 9.4 1.1 1 0 0 1 1 1 0 FHIPEP family SARAF PF06682.12 CDJ48126.1 - 1.9 8.1 14.2 2.2 7.9 14.2 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Velvet PF11754.8 CDJ48126.1 - 2.4 8.0 14.0 2.9 7.8 14.0 1.1 1 0 0 1 1 1 0 Velvet factor SOBP PF15279.6 CDJ48126.1 - 2.5 8.6 18.9 3 8.4 18.9 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF5521 PF17659.1 CDJ48126.1 - 3.2 5.5 11.9 3.4 5.4 11.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Zea_mays_MuDR PF05928.11 CDJ48126.1 - 3.6 7.2 9.1 4 7.0 9.1 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) UPF0688 PF15772.5 CDJ48126.1 - 4.5 7.5 20.4 5.1 7.3 20.4 1.0 1 0 0 1 1 1 0 UPF0688 family Neur_chan_memb PF02932.16 CDJ48126.1 - 5.3 7.0 14.4 6.5 6.7 14.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF913 PF06025.12 CDJ48126.1 - 5.6 5.8 10.0 6.3 5.7 10.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BAF1_ABF1 PF04684.13 CDJ48126.1 - 6.2 5.7 23.3 8.5 5.3 23.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor YjbH PF06082.11 CDJ48126.1 - 7.3 5.3 16.2 8.6 5.0 16.2 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Hydin_ADK PF17213.3 CDJ48126.1 - 9.5 6.4 19.0 14 5.9 19.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SR-25 PF10500.9 CDJ48127.1 - 1.5e-05 24.7 23.3 1.7e-05 24.6 23.3 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 CDJ48127.1 - 0.015 15.0 11.9 0.018 14.8 11.9 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2721 PF11026.8 CDJ48127.1 - 0.63 9.9 2.0 0.76 9.7 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) TCP PF03634.13 CDJ48127.1 - 1.1 9.9 18.1 1.1 9.8 18.1 1.0 1 0 0 1 1 1 0 TCP family transcription factor FAM199X PF15814.5 CDJ48127.1 - 1.7 7.6 19.4 1.9 7.5 19.4 1.0 1 0 0 1 1 1 0 Protein family FAM199X AAA_23 PF13476.6 CDJ48127.1 - 2.4 8.6 16.8 2.6 8.5 16.8 1.1 1 0 0 1 1 1 0 AAA domain DUF4603 PF15376.6 CDJ48127.1 - 2.6 5.3 17.9 2.9 5.2 17.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) PA26 PF04636.13 CDJ48127.1 - 2.8 6.7 15.4 3 6.6 15.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Peptidase_S49_N PF08496.10 CDJ48127.1 - 9.1 6.3 13.6 9.3 6.3 13.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BAF1_ABF1 PF04684.13 CDJ48128.1 - 0.16 11.0 25.9 0.2 10.7 25.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mitofilin PF09731.9 CDJ48128.1 - 0.45 9.3 29.4 0.53 9.1 29.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SWIRM-assoc_2 PF16496.5 CDJ48128.1 - 1.7 7.4 17.7 2.3 7.0 17.7 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal TFIIA PF03153.13 CDJ48128.1 - 2.8 7.8 38.8 4.4 7.2 38.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hph PF13694.6 CDJ48128.1 - 5.6 7.2 18.3 0.37 11.1 9.5 2.0 1 1 1 2 2 2 0 Sec63/Sec62 complex-interacting family Arf PF00025.21 CDJ48129.1 - 1.3e-15 57.3 0.0 1.4e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CDJ48129.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 Ras family RskA PF10099.9 CDJ48131.1 - 0.023 15.0 0.2 0.023 15.0 0.2 3.1 1 1 2 3 3 2 0 Anti-sigma-K factor rskA Lin-8 PF03353.15 CDJ48131.1 - 0.023 14.2 13.5 0.03 13.9 13.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Piezo_RRas_bdg PF12166.8 CDJ48131.1 - 0.03 13.6 4.0 0.041 13.2 4.0 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Velvet PF11754.8 CDJ48131.1 - 0.057 13.3 9.5 0.07 13.1 9.5 1.1 1 0 0 1 1 1 0 Velvet factor SARAF PF06682.12 CDJ48131.1 - 0.072 12.7 12.9 0.1 12.3 12.9 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Presenilin PF01080.17 CDJ48131.1 - 0.33 9.7 14.5 0.37 9.5 14.5 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ48131.1 - 0.57 10.0 14.5 0.99 9.2 14.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PCM1_C PF15717.5 CDJ48131.1 - 0.63 8.7 17.0 0.83 8.3 17.0 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus DDHD PF02862.17 CDJ48131.1 - 0.8 9.8 9.5 1.1 9.4 9.5 1.4 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.9 CDJ48131.1 - 0.95 7.6 25.8 1.1 7.4 25.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ48131.1 - 1.9 6.7 13.0 2.4 6.3 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.6 CDJ48131.1 - 2.2 8.2 8.6 3 7.8 8.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A MDFI PF15316.6 CDJ48131.1 - 2.7 8.0 8.6 3.6 7.7 8.6 1.3 1 0 0 1 1 1 0 MyoD family inhibitor DUF2828 PF11443.8 CDJ48131.1 - 4.3 5.3 12.3 5 5.1 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Plasmodium_Vir PF05795.11 CDJ48131.1 - 4.7 6.5 5.6 6.2 6.1 5.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SLC12 PF03522.15 CDJ48131.1 - 4.8 6.1 14.9 5.8 5.8 14.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 V_ATPase_I PF01496.19 CDJ48131.1 - 5.5 4.8 13.1 6.8 4.5 13.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YABBY PF04690.13 CDJ48131.1 - 8.3 6.9 9.0 12 6.5 9.0 1.3 1 0 0 1 1 1 0 YABBY protein MACPF PF01823.19 CDJ48132.1 - 0.13 12.3 12.6 3.8 7.6 0.0 3.3 3 1 0 3 3 3 0 MAC/Perforin domain DUF3446 PF11928.8 CDJ48133.1 - 0.023 15.0 11.7 0.023 15.0 11.7 3.2 2 1 0 2 2 1 0 Early growth response N-terminal domain RSRP PF17069.5 CDJ48133.1 - 0.046 13.3 18.8 0.077 12.6 18.8 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 BAF1_ABF1 PF04684.13 CDJ48133.1 - 0.083 11.9 18.9 0.12 11.4 18.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Hamartin PF04388.12 CDJ48133.1 - 0.17 10.6 23.2 0.2 10.3 23.2 1.0 1 0 0 1 1 1 0 Hamartin protein Peptidase_S64 PF08192.11 CDJ48133.1 - 0.36 9.3 27.0 0.46 8.9 27.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 CDJ48133.1 - 0.62 8.7 22.7 0.83 8.3 22.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.6 CDJ48133.1 - 2.4 8.7 26.8 3.4 8.2 26.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SR-25 PF10500.9 CDJ48133.1 - 3.4 7.2 45.6 1.1e+02 2.3 42.3 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Med15 PF09606.10 CDJ48133.1 - 4.3 5.9 42.2 5.3 5.6 42.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AF-4 PF05110.13 CDJ48133.1 - 5.5 4.9 40.2 7.7 4.5 40.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SMYLE_N PF18615.1 CDJ48133.1 - 6 6.3 23.7 8 5.9 23.7 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PAT1 PF09770.9 CDJ48133.1 - 7.2 4.7 35.6 8.7 4.5 35.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 CDJ48134.1 - 2.1e-09 37.9 23.4 3.1e-09 37.3 23.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ48134.1 - 0.00066 18.4 2.0 0.00066 18.4 2.0 2.1 2 0 0 2 2 1 1 Macoilin family SUIM_assoc PF16619.5 CDJ48134.1 - 0.45 10.6 0.0 0.097 12.7 6.4 4.8 4 1 0 4 4 2 0 Unstructured region C-term to UIM in Ataxin3 DAG_kinase_N PF14513.6 CDJ48134.1 - 1.3 9.2 24.0 0.058 13.6 4.1 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Cwf_Cwc_15 PF04889.12 CDJ48134.1 - 1.5 8.5 22.5 2 8.1 5.5 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GAGA_bind PF06217.12 CDJ48134.1 - 3.7 7.7 22.5 6.3 7.0 22.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF572 PF04502.13 CDJ48134.1 - 3.7 7.1 26.9 5.2 6.6 26.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) BORG_CEP PF14957.6 CDJ48134.1 - 5 8.3 21.3 10 7.3 1.3 2.2 2 0 0 2 2 2 0 Cdc42 effector Bestrophin PF01062.21 CDJ48134.1 - 8.4 5.7 10.6 0.45 9.9 5.1 1.6 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Ly49 PF08391.10 CDJ48134.1 - 9.4 6.6 15.2 18 5.7 12.1 2.4 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region DUF4569 PF15133.6 CDJ48134.1 - 9.4 5.9 23.8 0.51 10.0 5.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) FAM117 PF15388.6 CDJ48134.1 - 9.7 5.5 26.2 16 4.8 26.2 1.3 1 0 0 1 1 1 0 Protein Family FAM117 TFIIA PF03153.13 CDJ48135.1 - 0.12 12.3 11.8 0.14 12.1 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ48135.1 - 0.13 11.8 13.4 0.18 11.4 13.4 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ48135.1 - 0.5 9.3 9.4 0.61 9.0 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ48135.1 - 2 7.3 20.9 2.6 6.9 20.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Androgen_recep PF02166.16 CDJ48135.1 - 5.5 5.7 13.0 6.9 5.4 13.0 1.2 1 0 0 1 1 1 0 Androgen receptor SID-1_RNA_chan PF13965.6 CDJ48136.1 - 0.043 12.2 11.5 0.052 12.0 11.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 CDJ48136.1 - 0.055 11.7 33.5 0.055 11.7 33.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAP1 PF07218.11 CDJ48136.1 - 0.092 11.0 6.8 0.091 11.0 6.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TFIIA PF03153.13 CDJ48136.1 - 0.47 10.4 54.7 0.56 10.1 54.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FHIPEP PF00771.20 CDJ48136.1 - 2.8 6.3 10.0 4.7 5.6 10.0 1.4 1 0 0 1 1 1 0 FHIPEP family CCSAP PF15748.5 CDJ48136.1 - 4.3 7.4 33.8 6.2 6.9 33.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Hamartin PF04388.12 CDJ48136.1 - 5 5.7 26.2 5.6 5.5 26.2 1.0 1 0 0 1 1 1 0 Hamartin protein Serinc PF03348.15 CDJ48136.1 - 7.4 5.4 11.4 8.1 5.2 11.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peptidase_S49_N PF08496.10 CDJ48136.1 - 7.5 6.6 13.4 13 5.8 13.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.14 CDJ48137.1 - 1.3 7.2 34.4 1.5 7.0 34.4 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ48137.1 - 1.4 8.7 37.1 1.6 8.5 37.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.7 CDJ48137.1 - 1.7 8.9 44.3 2.1 8.6 44.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF913 PF06025.12 CDJ48137.1 - 2.6 6.9 19.4 3.6 6.5 19.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM60A PF15396.6 CDJ48137.1 - 4.9 7.1 30.0 5.7 6.9 30.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 CDJ48137.1 - 5.3 6.0 37.5 6.3 5.7 37.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 CDJ48137.1 - 5.8 5.6 29.5 6.1 5.6 29.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 CDJ48137.1 - 6.6 5.4 44.4 8 5.1 44.4 1.0 1 0 0 1 1 1 0 Presenilin DAG_kinase_N PF14513.6 CDJ48137.1 - 9 6.5 32.2 10 6.3 32.2 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Spt20 PF12090.8 CDJ48138.1 - 0.024 14.3 64.5 0.034 13.8 32.3 2.6 2 0 0 2 2 2 0 Spt20 family VitD-bind_III PF09164.10 CDJ48138.1 - 0.33 11.0 4.2 1.2 9.2 2.3 3.0 2 0 0 2 2 2 0 Vitamin D binding protein, domain III EPL1 PF10513.9 CDJ48138.1 - 1.8 8.9 21.2 5.6 7.3 9.9 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like SAGA-Tad1 PF12767.7 CDJ48138.1 - 1.9 8.1 18.8 1.3 8.7 1.0 2.7 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit Cullin PF00888.22 CDJ48139.1 - 1.9e-116 390.2 5.7 4.3e-116 389.0 5.7 1.5 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ48139.1 - 2.9e-22 78.5 0.6 9.7e-22 76.8 0.2 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain PKD_channel PF08016.12 CDJ48140.1 - 2.3e-05 23.3 0.6 2.3e-05 23.3 0.6 3.0 3 0 0 3 3 3 1 Polycystin cation channel DUF262 PF03235.14 CDJ48140.1 - 0.078 13.1 1.5 0.22 11.7 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF262 Kinesin PF00225.23 CDJ48141.1 - 5.8e-88 295.0 0.0 1.6e-86 290.3 0.0 2.3 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ48141.1 - 2.1e-20 73.2 0.1 6.3e-20 71.6 0.1 1.8 1 1 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 CDJ48141.1 - 0.00024 21.5 0.0 0.0011 19.4 0.0 2.2 2 0 0 2 2 2 1 Kinesin protein 1B Kinesin_assoc PF16183.5 CDJ48141.1 - 0.0068 16.6 7.2 0.0082 16.3 0.1 2.9 2 1 0 2 2 2 1 Kinesin-associated zf-C4H2 PF10146.9 CDJ48141.1 - 0.82 9.9 6.2 2.1 8.6 6.2 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein AAA_13 PF13166.6 CDJ48141.1 - 9 4.8 12.8 3.2 6.3 9.1 1.9 2 0 0 2 2 2 0 AAA domain PKD_channel PF08016.12 CDJ48142.1 - 2.3e-11 43.0 28.5 1.7e-08 33.6 10.6 2.9 3 0 0 3 3 3 2 Polycystin cation channel AMP-binding PF00501.28 CDJ48143.1 - 6.8e-13 48.0 0.0 1.1e-11 44.0 0.0 2.4 2 1 0 2 2 2 1 AMP-binding enzyme zf-C2H2_2 PF12756.7 CDJ48144.1 - 1.4e-16 60.7 1.0 1.4e-16 60.7 1.0 1.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) FAS_I_H PF18314.1 CDJ48144.1 - 0.039 13.6 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain Mito_carr PF00153.27 CDJ48145.1 - 6.6e-57 189.4 6.4 3.2e-23 81.4 0.0 4.8 4 1 1 5 5 5 4 Mitochondrial carrier protein SUIM_assoc PF16619.5 CDJ48145.1 - 6.6 6.9 14.5 2 8.6 2.7 3.6 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ48145.1 - 8.8 5.9 13.4 26 4.3 13.4 1.8 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PT-VENN PF04829.13 CDJ48146.1 - 1.1 9.4 5.2 1.8 8.7 5.2 1.3 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Exonuc_VII_L PF02601.15 CDJ48147.1 - 0.094 12.3 0.1 0.094 12.3 0.1 4.0 3 2 0 3 3 3 0 Exonuclease VII, large subunit DUF4746 PF15928.5 CDJ48149.1 - 0.00014 21.4 2.4 0.00014 21.4 2.4 2.9 1 1 2 3 3 3 1 Domain of unknown function (DUF4746) Presenilin PF01080.17 CDJ48149.1 - 0.00021 20.2 37.6 0.00021 20.2 37.6 2.4 2 0 0 2 2 2 1 Presenilin RAP1 PF07218.11 CDJ48149.1 - 0.072 11.4 8.3 0.095 11.0 8.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CRT10 PF08728.10 CDJ48149.1 - 0.11 10.7 13.2 0.11 10.7 13.2 1.2 1 0 0 1 1 1 0 CRT10 LptF_LptG PF03739.14 CDJ48149.1 - 0.21 10.4 11.5 0.41 9.4 11.5 1.5 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Mem_trans PF03547.18 CDJ48149.1 - 3.1 6.1 9.2 5.5 5.3 9.2 1.6 1 0 0 1 1 1 0 Membrane transport protein ALMT PF11744.8 CDJ48149.1 - 3.4 6.4 34.0 0.22 10.3 27.8 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter CDC45 PF02724.14 CDJ48149.1 - 3.5 5.8 45.9 0.26 9.5 37.3 2.1 2 0 0 2 2 2 0 CDC45-like protein CD20 PF04103.15 CDJ48149.1 - 4.3 7.4 13.2 9.3e+02 -0.2 0.0 3.2 2 1 0 2 2 2 0 CD20-like family Shadoo PF14999.6 CDJ48149.1 - 4.7 7.3 32.8 3 7.9 3.5 3.2 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective DivIC PF04977.15 CDJ48150.1 - 0.031 14.1 5.1 0.034 13.9 5.1 1.1 1 0 0 1 1 1 0 Septum formation initiator Spt20 PF12090.8 CDJ48150.1 - 0.062 12.9 14.6 0.062 12.9 14.6 1.0 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ48150.1 - 0.19 10.9 9.6 0.18 11.0 9.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2722 PF10846.8 CDJ48150.1 - 0.33 9.9 12.6 0.32 9.9 12.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) G0-G1_switch_2 PF15103.6 CDJ48150.1 - 0.82 10.1 5.0 0.86 10.1 5.0 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 Med19 PF10278.9 CDJ48150.1 - 0.97 9.3 10.8 1.1 9.2 10.8 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Androgen_recep PF02166.16 CDJ48150.1 - 1.1 8.0 12.4 1.1 8.1 12.4 1.1 1 0 0 1 1 1 0 Androgen receptor DUF4834 PF16118.5 CDJ48150.1 - 4.7 8.2 11.8 5.7 8.0 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3824 PF12868.7 CDJ48152.1 - 0.014 16.1 5.8 0.014 16.1 5.8 2.2 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) BLOC1S3 PF15753.5 CDJ48152.1 - 0.029 14.5 2.0 0.033 14.3 2.0 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 FAM101 PF15068.6 CDJ48152.1 - 0.044 13.7 1.9 0.05 13.6 1.5 1.3 1 1 0 1 1 1 0 FAM101 family Trp_oprn_chp PF09534.10 CDJ48152.1 - 0.049 13.4 16.7 0.071 12.9 16.7 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Spt20 PF12090.8 CDJ48152.1 - 0.055 13.1 2.9 0.058 13.0 2.9 1.1 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ48152.1 - 0.079 12.0 2.9 0.085 11.9 2.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ48152.1 - 0.86 9.5 8.2 1 9.3 8.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5521 PF17659.1 CDJ48152.1 - 3 5.6 5.9 3.1 5.5 5.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) MT-A70 PF05063.14 CDJ48153.1 - 1.6e-43 148.6 0.1 1.6e-43 148.6 0.1 1.7 2 0 0 2 2 2 1 MT-A70 TIM PF00121.18 CDJ48154.1 - 1.9e-36 125.7 0.2 2.1e-36 125.5 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MreB_Mbl PF06723.13 CDJ48154.1 - 0.063 12.1 0.2 0.23 10.2 0.1 1.7 1 1 1 2 2 2 0 MreB/Mbl protein Lsr2 PF11774.8 CDJ48154.1 - 0.15 12.2 0.2 0.24 11.6 0.2 1.4 1 0 0 1 1 1 0 Lsr2 DUF4667 PF15700.5 CDJ48155.1 - 0.0029 17.7 1.1 0.0029 17.7 1.1 3.0 2 1 1 3 3 2 1 Domain of unknown function (DUF4667) TCP PF03634.13 CDJ48155.1 - 0.011 16.3 16.7 0.12 12.9 8.5 2.4 2 0 0 2 2 2 0 TCP family transcription factor SOG2 PF10428.9 CDJ48155.1 - 0.065 12.4 27.9 0.1 11.8 27.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein FTZ PF03867.14 CDJ48155.1 - 0.081 12.5 20.7 0.18 11.3 17.5 2.4 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region Apt1 PF10351.9 CDJ48155.1 - 0.23 10.3 19.8 0.34 9.7 1.0 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4614 PF15391.6 CDJ48155.1 - 0.52 10.3 31.7 0.63 10.0 16.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Spt20 PF12090.8 CDJ48155.1 - 0.65 9.6 22.1 0.039 13.6 15.3 2.1 2 0 0 2 2 2 0 Spt20 family Roughex PF06020.11 CDJ48155.1 - 1.5 7.9 8.9 2.8 7.0 8.9 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Filament_head PF04732.14 CDJ48155.1 - 2.1 9.3 40.3 5.8 7.9 10.5 2.7 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region SurA_N_3 PF13624.6 CDJ48155.1 - 2.3 8.0 10.9 0.87 9.4 6.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain DUF4207 PF13904.6 CDJ48155.1 - 2.7 7.6 19.9 0.4 10.3 10.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) CDC45 PF02724.14 CDJ48155.1 - 2.8 6.1 9.5 0.68 8.2 5.1 1.8 2 0 0 2 2 2 0 CDC45-like protein Presenilin PF01080.17 CDJ48155.1 - 4.4 6.0 16.9 5 5.8 12.3 2.2 2 0 0 2 2 2 0 Presenilin Caldesmon PF02029.15 CDJ48156.1 - 0.32 9.7 41.0 0.39 9.4 41.0 1.1 1 0 0 1 1 1 0 Caldesmon C2-C2_1 PF11618.8 CDJ48157.1 - 0.013 15.6 1.4 0.018 15.1 1.4 1.4 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 Ribosomal_60s PF00428.19 CDJ48157.1 - 0.028 15.0 5.3 0.028 15.0 5.3 3.2 2 1 0 2 2 2 0 60s Acidic ribosomal protein DUF4342 PF14242.6 CDJ48157.1 - 0.52 10.3 0.1 0.52 10.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) CSG2 PF16965.5 CDJ48157.1 - 0.81 8.6 3.8 0.84 8.5 3.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator V_ATPase_I PF01496.19 CDJ48157.1 - 1.1 7.1 11.0 0.96 7.3 11.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3402 PF11882.8 CDJ48157.1 - 1.1 8.2 12.8 1.3 8.0 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) SID-1_RNA_chan PF13965.6 CDJ48157.1 - 1.2 7.5 2.3 1.1 7.6 2.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF-3_zeta PF05091.12 CDJ48157.1 - 2 7.3 16.3 1.9 7.3 16.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 CDJ48157.1 - 5.1 6.8 11.4 8.1 6.1 11.4 1.3 1 0 0 1 1 1 0 Connexin DUF1764 PF08576.10 CDJ48157.1 - 7.7 7.5 16.8 39 5.2 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Ribosomal_S15 PF00312.22 CDJ48158.1 - 0.00043 20.4 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 TFIIA PF03153.13 CDJ48158.1 - 0.0042 17.1 26.0 0.0051 16.9 26.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ48158.1 - 0.016 13.5 15.8 0.02 13.2 15.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2722 PF10846.8 CDJ48158.1 - 0.041 12.8 14.0 0.059 12.3 14.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 CDJ48158.1 - 0.056 12.4 5.7 0.061 12.3 5.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hamartin PF04388.12 CDJ48158.1 - 0.13 10.9 6.7 0.15 10.7 6.7 1.1 1 0 0 1 1 1 0 Hamartin protein Spt20 PF12090.8 CDJ48158.1 - 0.14 11.8 20.5 0.21 11.1 20.5 1.2 1 0 0 1 1 1 0 Spt20 family DUF4551 PF15087.6 CDJ48158.1 - 0.14 10.9 6.7 0.17 10.7 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Band_3_cyto PF07565.13 CDJ48158.1 - 0.15 11.8 4.0 0.23 11.2 4.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Med15 PF09606.10 CDJ48158.1 - 0.17 10.6 22.2 0.17 10.5 22.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal EOS1 PF12326.8 CDJ48158.1 - 0.2 11.6 0.5 0.27 11.2 0.5 1.2 1 0 0 1 1 1 0 N-glycosylation protein Neur_chan_memb PF02932.16 CDJ48158.1 - 0.6 10.1 3.5 0.77 9.8 3.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC27 PF09507.10 CDJ48158.1 - 0.62 9.4 12.6 0.84 8.9 12.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4770 PF15994.5 CDJ48158.1 - 0.83 9.9 6.2 1.2 9.4 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) RR_TM4-6 PF06459.12 CDJ48158.1 - 1.1 9.0 7.3 1.3 8.8 7.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3408 PF11888.8 CDJ48158.1 - 1.2 9.3 9.1 1.9 8.6 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Roughex PF06020.11 CDJ48158.1 - 1.2 8.1 11.6 1.7 7.6 11.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Myc_N PF01056.18 CDJ48158.1 - 1.4 8.8 9.8 1.9 8.3 9.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Presenilin PF01080.17 CDJ48158.1 - 1.4 7.6 10.7 1.8 7.2 10.7 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ48158.1 - 1.6 5.8 8.9 1.6 5.8 8.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Connexin PF00029.19 CDJ48158.1 - 1.8 8.3 2.9 2.3 7.9 2.9 1.2 1 0 0 1 1 1 0 Connexin TERB2 PF15101.6 CDJ48158.1 - 2.3 8.2 8.0 3.8 7.5 8.0 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Suf PF05843.14 CDJ48158.1 - 4.1 7.3 11.5 5.6 6.8 11.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) V_ATPase_I PF01496.19 CDJ48158.1 - 4.3 5.1 4.9 5.3 4.8 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4746 PF15928.5 CDJ48158.1 - 7.2 5.9 8.5 10 5.4 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol3_delta2 PF13177.6 CDJ48159.1 - 8e-12 45.2 0.1 1.1e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CDJ48159.1 - 9.2e-09 35.6 0.0 3.5e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 CDJ48159.1 - 3.6e-06 27.4 0.1 7.5e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 CDJ48159.1 - 9e-05 22.7 0.1 0.00045 20.5 0.0 2.2 3 0 0 3 3 3 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 CDJ48159.1 - 0.00027 20.7 0.0 0.00041 20.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase III, delta subunit MCM PF00493.23 CDJ48159.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_14 PF13173.6 CDJ48159.1 - 0.027 14.5 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 CDJ48159.1 - 0.084 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase Ribosomal_L31e PF01198.19 CDJ48160.1 - 5.5e-19 68.2 0.4 9.4e-19 67.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e TFIIA PF03153.13 CDJ48160.1 - 0.014 15.4 21.5 0.018 15.1 21.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ48160.1 - 0.054 12.2 4.1 0.063 12.0 4.1 1.2 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 CDJ48160.1 - 0.054 12.5 2.8 0.071 12.1 2.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4175 PF13779.6 CDJ48160.1 - 0.13 10.2 19.4 0.15 9.9 19.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ATG22 PF11700.8 CDJ48160.1 - 0.21 10.1 0.9 0.28 9.8 0.9 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Serinc PF03348.15 CDJ48160.1 - 0.35 9.7 1.4 0.45 9.4 1.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CDK2AP PF09806.9 CDJ48160.1 - 1.3 9.0 10.1 2.1 8.4 10.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SbcCD_C PF13558.6 CDJ48160.1 - 1.4 9.3 4.6 0.76 10.1 1.2 2.0 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit Med15 PF09606.10 CDJ48160.1 - 2 7.0 27.6 2.6 6.6 27.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4484 PF14831.6 CDJ48160.1 - 2 8.4 7.6 2.7 8.0 7.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) PIP5K PF01504.18 CDJ48160.1 - 9.7 5.3 9.3 14 4.8 9.3 1.3 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SHR-BD PF06650.12 CDJ48161.1 - 0.00047 19.6 0.0 0.0043 16.5 0.0 2.4 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 SUIM_assoc PF16619.5 CDJ48162.1 - 1.6e-16 60.1 0.0 0.00068 19.6 0.0 6.7 6 1 0 6 6 6 3 Unstructured region C-term to UIM in Ataxin3 Chorein_N PF12624.7 CDJ48162.1 - 1.1e-09 38.4 2.4 1.5e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 Myb_DNA-binding PF00249.31 CDJ48163.1 - 7.3e-23 80.5 4.7 7.1e-13 48.5 1.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ48163.1 - 2.7e-20 72.4 4.8 1.1e-13 51.2 2.0 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 CDJ48163.1 - 0.0085 16.2 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 CDJ48163.1 - 0.02 14.9 0.1 0.73 9.9 0.0 2.1 1 1 1 2 2 2 0 SLIDE DUF722 PF05263.11 CDJ48163.1 - 0.038 14.2 0.1 0.067 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Myb_Cef PF11831.8 CDJ48164.1 - 9e-19 68.0 3.2 9e-19 68.0 3.2 4.9 4 2 0 4 4 4 1 pre-mRNA splicing factor component Phosducin PF02114.16 CDJ48164.1 - 4.1 6.3 7.8 0.37 9.7 2.6 1.8 2 0 0 2 2 2 0 Phosducin Got1 PF04178.12 CDJ48165.1 - 9.9e-31 106.5 20.1 1.4e-30 106.0 20.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Lectin_leg-like PF03388.13 CDJ48166.1 - 9.9e-12 44.7 0.4 3.5e-11 42.9 0.4 1.9 1 1 0 1 1 1 1 Legume-like lectin family Asn_synthase PF00733.21 CDJ48167.1 - 3.2e-12 46.8 5.3 0.0007 19.4 0.1 3.3 2 1 1 3 3 3 3 Asparagine synthase Asp PF00026.23 CDJ48168.1 - 0.00038 20.0 0.0 0.00055 19.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF4926 PF16277.5 CDJ48168.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) PNKP-ligase_C PF16536.5 CDJ48168.1 - 0.2 11.9 0.1 0.34 11.2 0.1 1.3 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, C-terminal region DUF5562 PF17717.1 CDJ48170.1 - 0.023 14.7 2.7 0.043 13.8 0.4 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5562) AAA_12 PF13087.6 CDJ48171.1 - 5.6e-33 114.3 0.0 6.8e-25 87.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CDJ48171.1 - 1.8e-07 31.2 0.1 4.1e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ48171.1 - 0.00011 22.5 0.2 0.00082 19.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_lid_9 PF17871.1 CDJ48172.1 - 4.2e-30 103.8 0.0 8.7e-30 102.7 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain Clp_N PF02861.20 CDJ48172.1 - 2.9e-17 62.5 2.7 2.3e-09 37.2 0.3 3.1 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA PF00004.29 CDJ48172.1 - 1.4e-13 51.4 0.0 3.4e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ48172.1 - 1.7e-08 35.0 0.1 2.5e-06 28.0 0.1 3.2 2 1 1 3 3 3 1 AAA ATPase domain TniB PF05621.11 CDJ48172.1 - 2.9e-06 26.8 0.1 0.0018 17.7 0.0 3.0 2 1 0 2 2 2 1 Bacterial TniB protein AAA_5 PF07728.14 CDJ48172.1 - 0.00038 20.5 0.2 0.0026 17.8 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CDJ48172.1 - 0.00068 19.6 0.2 1.3 8.9 0.1 2.4 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CDJ48172.1 - 0.00073 19.8 0.0 0.014 15.7 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 CDJ48172.1 - 0.0049 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CDJ48172.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CDJ48172.1 - 0.015 14.9 0.1 0.056 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDJ48172.1 - 0.032 13.8 0.0 0.095 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 CDJ48172.1 - 0.064 12.4 0.0 0.15 11.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 CDJ48172.1 - 0.09 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 CDJ48172.1 - 0.16 12.6 0.1 1.4 9.5 0.0 2.5 2 1 1 3 3 3 0 AAA domain AAA_2 PF07724.14 CDJ48173.1 - 9.3e-51 172.3 0.0 3e-50 170.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 CDJ48173.1 - 9.7e-21 73.6 0.4 4.2e-20 71.6 0.4 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CDJ48173.1 - 5.7e-11 42.6 0.0 1.5e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ48173.1 - 4.5e-10 40.1 0.0 1.4e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ48173.1 - 3.3e-07 30.2 0.0 2.2e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 CDJ48173.1 - 0.00053 19.8 0.0 0.0028 17.4 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta2 PF13177.6 CDJ48173.1 - 0.00095 19.0 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III, delta subunit RsgA_GTPase PF03193.16 CDJ48173.1 - 0.0026 17.7 0.0 1 9.3 0.0 3.1 2 1 1 3 3 3 1 RsgA GTPase AAA_7 PF12775.7 CDJ48173.1 - 0.0034 16.9 0.0 0.0068 15.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 CDJ48173.1 - 0.0085 16.6 1.6 0.034 14.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 CDJ48173.1 - 0.0088 16.2 3.4 0.016 15.3 0.0 2.7 2 1 0 2 2 2 1 Helicase HerA, central domain AAA_14 PF13173.6 CDJ48173.1 - 0.011 15.8 0.0 0.04 14.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 CDJ48173.1 - 0.011 15.1 0.0 0.038 13.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 CDJ48173.1 - 0.018 15.6 0.1 0.078 13.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter T2SSE PF00437.20 CDJ48173.1 - 0.019 14.1 0.0 0.044 12.9 0.0 1.7 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_3 PF07726.11 CDJ48173.1 - 0.019 14.8 0.0 0.27 11.1 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CDJ48173.1 - 0.023 14.1 0.0 2.2 7.6 0.0 2.5 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CDJ48173.1 - 0.04 14.2 0.1 0.04 14.2 0.1 2.9 3 1 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 CDJ48173.1 - 0.052 13.4 0.5 0.2 11.6 0.0 2.2 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea Fmp27_WPPW PF10359.9 CDJ48173.1 - 0.13 11.1 3.6 0.23 10.3 3.6 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Torsin PF06309.11 CDJ48173.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 Torsin Sulfatase_C PF14707.6 CDJ48173.1 - 0.22 12.2 1.9 0.44 11.3 0.7 2.1 2 0 0 2 2 1 0 C-terminal region of aryl-sulfatase AAA_16 PF13191.6 CDJ48173.1 - 0.36 11.2 8.3 0.052 13.9 1.1 3.3 2 2 0 2 2 2 0 AAA ATPase domain BLOC1_2 PF10046.9 CDJ48173.1 - 0.57 10.5 5.6 9.9 6.5 0.3 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 CDJ48173.1 - 3.2 7.0 8.1 0.42 9.9 3.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) COPI_C PF06957.11 CDJ48174.1 - 2.6e-76 257.0 0.0 3.6e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 CDJ48174.1 - 1.6e-72 245.0 0.0 3.4e-72 243.9 0.0 1.5 1 1 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CDJ48174.1 - 7.1e-38 127.9 17.8 2.5e-07 31.3 0.4 7.5 8 0 0 8 8 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ48174.1 - 7.7e-13 48.6 0.1 2.9e-07 30.7 0.0 5.0 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NRBF2_MIT PF17169.4 CDJ48174.1 - 0.0088 16.2 0.3 0.025 14.8 0.3 1.7 1 0 0 1 1 1 1 MIT domain of nuclear receptor-binding factor 2 Nup160 PF11715.8 CDJ48174.1 - 0.059 12.0 10.8 1.2 7.7 0.3 3.8 2 1 1 4 4 4 0 Nucleoporin Nup120/160 ArsC PF03960.15 CDJ48174.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 ArsC family TPR_2 PF07719.17 CDJ48174.1 - 0.07 13.3 5.4 5.1 7.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Nucleoporin_N PF08801.11 CDJ48174.1 - 0.11 11.2 0.1 0.33 9.6 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like TPR_16 PF13432.6 CDJ48174.1 - 1.5 9.6 5.8 44 4.9 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ48174.1 - 1.5 9.4 6.8 3.7 8.1 1.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ48174.1 - 5.1 8.2 11.8 46 5.2 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat Efg1 PF10153.9 CDJ48175.1 - 7.1e-12 45.7 4.6 7.1e-12 45.7 4.6 3.0 4 0 0 4 4 4 1 rRNA-processing protein Efg1 FlgN PF05130.12 CDJ48175.1 - 0.55 10.7 8.5 0.59 10.6 0.3 2.4 2 0 0 2 2 2 0 FlgN protein Maf PF02545.14 CDJ48176.1 - 4.9e-22 78.5 0.0 2.1e-10 40.7 0.0 2.7 2 1 0 2 2 2 2 Maf-like protein DSPc PF00782.20 CDJ48177.1 - 3.2e-06 27.0 0.0 6.5e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ48177.1 - 0.0039 16.8 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Glyco_trans_4_4 PF13579.6 CDJ48177.1 - 0.043 14.3 2.5 0.11 12.9 2.5 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain zf-met2 PF12907.7 CDJ48178.1 - 2.2e-19 69.3 3.0 2.2e-19 69.3 3.0 1.7 2 0 0 2 2 2 1 Zinc-binding 4F5 PF04419.14 CDJ48178.1 - 9.8e-05 23.2 3.6 9.8e-05 23.2 3.6 1.9 2 0 0 2 2 2 1 4F5 protein family Macoilin PF09726.9 CDJ48179.1 - 0.38 9.3 10.8 1.1 7.7 10.8 1.8 1 0 0 1 1 1 0 Macoilin family DUF572 PF04502.13 CDJ48179.1 - 1.3 8.6 14.8 2.4 7.7 14.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DDHD PF02862.17 CDJ48179.1 - 9.3 6.3 10.2 28 4.8 10.2 1.9 1 0 0 1 1 1 0 DDHD domain NOC3p PF07540.11 CDJ48180.1 - 1.3e-11 44.7 1.2 1.3e-11 44.7 1.2 3.2 3 1 0 3 3 3 1 Nucleolar complex-associated protein DUF755 PF05501.11 CDJ48180.1 - 0.068 13.5 41.0 0.057 13.7 18.6 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF755) Arm PF00514.23 CDJ48181.1 - 0.041 13.9 35.2 0.041 13.9 0.1 7.3 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat LMBR1 PF04791.16 CDJ48183.1 - 0.00036 19.6 0.5 0.00037 19.5 0.5 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein SR-25 PF10500.9 CDJ48183.1 - 0.0046 16.6 3.2 0.0059 16.2 3.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4407 PF14362.6 CDJ48183.1 - 0.0081 15.6 7.6 0.011 15.1 7.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Hamartin PF04388.12 CDJ48183.1 - 0.012 14.4 10.3 0.014 14.1 10.3 1.1 1 0 0 1 1 1 0 Hamartin protein Bud13 PF09736.9 CDJ48183.1 - 0.034 14.6 6.3 0.043 14.2 6.3 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Anoctamin PF04547.12 CDJ48183.1 - 0.044 12.6 0.4 0.054 12.3 0.4 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF3533 PF12051.8 CDJ48183.1 - 0.053 12.4 3.1 0.059 12.3 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Suf PF05843.14 CDJ48183.1 - 0.054 13.5 8.7 0.066 13.2 8.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GET2 PF08690.10 CDJ48183.1 - 0.061 13.0 9.3 0.085 12.5 9.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIA PF03153.13 CDJ48183.1 - 0.061 13.3 27.0 0.073 13.1 27.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rxt3 PF08642.10 CDJ48183.1 - 0.094 13.5 3.5 0.076 13.8 2.2 1.5 2 0 0 2 2 1 0 Histone deacetylation protein Rxt3 Pex24p PF06398.11 CDJ48183.1 - 0.12 11.3 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Neur_chan_memb PF02932.16 CDJ48183.1 - 0.13 12.3 1.8 0.16 12.0 1.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OATP PF03137.20 CDJ48183.1 - 0.16 10.2 0.3 0.2 9.9 0.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Scs3p PF10261.9 CDJ48183.1 - 0.17 11.4 1.0 0.25 10.8 1.0 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2722 PF10846.8 CDJ48183.1 - 0.49 9.3 19.2 0.86 8.5 19.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FAM199X PF15814.5 CDJ48183.1 - 0.99 8.4 7.8 1.3 8.0 7.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X Spt20 PF12090.8 CDJ48183.1 - 1.3 8.6 25.9 1.9 8.0 25.9 1.3 1 0 0 1 1 1 0 Spt20 family Maf1 PF09174.10 CDJ48183.1 - 2.1 8.5 5.5 3.2 7.9 5.5 1.2 1 0 0 1 1 1 0 Maf1 regulator SWI-SNF_Ssr4 PF08549.10 CDJ48183.1 - 7.7 5.0 14.1 9.6 4.7 14.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PAT1 PF09770.9 CDJ48183.1 - 7.9 4.6 19.7 9.5 4.3 19.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TERB2 PF15101.6 CDJ48183.1 - 9.3 6.2 12.6 13 5.7 12.6 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Androgen_recep PF02166.16 CDJ48184.1 - 0.0032 16.4 11.1 0.0032 16.4 11.1 6.7 4 1 2 6 6 6 1 Androgen receptor RskA PF10099.9 CDJ48184.1 - 0.0076 16.6 8.3 0.0076 16.6 8.3 3.9 3 2 1 4 4 4 1 Anti-sigma-K factor rskA DnaJ PF00226.31 CDJ48184.1 - 0.014 15.5 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain EphA2_TM PF14575.6 CDJ48184.1 - 0.059 14.3 1.1 0.059 14.3 1.1 5.0 7 0 0 7 7 7 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 CDJ48184.1 - 0.064 12.0 0.4 0.15 10.8 0.4 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PIG-U PF06728.13 CDJ48184.1 - 0.16 11.0 10.8 0.27 10.2 10.8 1.3 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U DUF4330 PF14221.6 CDJ48184.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) LMF1 PF06762.14 CDJ48184.1 - 0.55 9.3 5.7 0.78 8.8 5.7 1.1 1 0 0 1 1 1 0 Lipase maturation factor DUF975 PF06161.11 CDJ48184.1 - 3.9 7.2 20.1 6.6 6.4 20.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF975) MSG PF02349.15 CDJ48185.1 - 0.023 14.9 0.8 0.048 13.8 0.8 1.6 1 0 0 1 1 1 0 Major surface glycoprotein Fungal_trans_2 PF11951.8 CDJ48185.1 - 0.11 11.3 3.2 1.1 8.0 0.1 2.0 1 1 1 2 2 2 0 Fungal specific transcription factor domain SF-assemblin PF06705.11 CDJ48185.1 - 0.17 11.2 7.7 0.53 9.6 1.0 2.0 1 1 1 2 2 2 0 SF-assemblin/beta giardin SUIM_assoc PF16619.5 CDJ48185.1 - 0.18 11.9 4.9 0.56 10.3 4.9 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Cortex-I_coil PF09304.10 CDJ48185.1 - 0.26 11.5 15.0 0.13 12.5 1.2 2.2 1 1 0 2 2 2 0 Cortexillin I, coiled coil DUF4407 PF14362.6 CDJ48185.1 - 1.4 8.2 17.1 0.88 8.9 15.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4376 PF14301.6 CDJ48185.1 - 1.5 9.3 12.6 1 9.8 8.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) Muted PF14942.6 CDJ48185.1 - 4.3 7.7 10.7 2.9 8.2 5.3 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein FAM184 PF15665.5 CDJ48185.1 - 7.4 6.3 18.4 51 3.5 18.4 2.0 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B DOR PF14839.6 CDJ48185.1 - 8.6 6.2 10.1 4.4 7.2 8.0 1.5 1 1 0 1 1 1 0 DOR family M16C_assoc PF08367.11 CDJ48185.1 - 8.9 5.4 11.9 0.06 12.5 3.7 1.5 2 0 0 2 2 2 0 Peptidase M16C associated Ribosomal_60s PF00428.19 CDJ48186.1 - 0.96 10.1 8.1 1.8 9.2 8.1 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein FAM60A PF15396.6 CDJ48188.1 - 0.065 13.2 30.9 0.1 12.6 30.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4045 PF13254.6 CDJ48188.1 - 0.56 9.8 36.8 0.68 9.5 36.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Presenilin PF01080.17 CDJ48188.1 - 1.4 7.6 51.1 2.1 7.0 51.1 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ48188.1 - 1.8 7.5 44.7 1.8 7.5 44.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 CDJ48188.1 - 2.5 6.3 38.6 3.1 6.0 38.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 CDJ48188.1 - 6 4.9 46.2 7 4.7 46.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.6 CDJ48188.1 - 6.5 5.5 32.6 7.5 5.2 32.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.9 CDJ48188.1 - 8.6 4.8 34.1 11 4.4 34.1 1.1 1 0 0 1 1 1 0 Macoilin family Form_Nir_trans PF01226.17 CDJ48189.1 - 9.2e-60 201.9 22.9 9.2e-60 201.9 22.9 1.9 2 0 0 2 2 2 1 Formate/nitrite transporter Ribosomal_60s PF00428.19 CDJ48189.1 - 3.8 8.2 16.5 11 6.7 16.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein AAA PF00004.29 CDJ48190.1 - 4e-32 111.4 0.1 7.8e-32 110.5 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ48190.1 - 3.3e-14 52.4 0.2 5.6e-14 51.7 0.2 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ48190.1 - 1.6e-06 28.2 0.1 1.2e-05 25.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDJ48190.1 - 3.2e-06 27.4 0.0 6.1e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CDJ48190.1 - 4.2e-06 27.2 0.5 0.00011 22.7 0.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CDJ48190.1 - 1.1e-05 25.2 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CDJ48190.1 - 8e-05 23.2 0.0 0.00016 22.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ48190.1 - 0.00019 21.7 0.8 0.0074 16.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CDJ48190.1 - 0.00093 19.4 0.1 0.002 18.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CDJ48190.1 - 0.0018 18.0 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 CDJ48190.1 - 0.002 17.9 0.1 0.0082 15.9 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 CDJ48190.1 - 0.003 17.4 0.0 0.011 15.6 0.0 2.0 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 CDJ48190.1 - 0.0038 17.4 0.0 0.011 15.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.13 CDJ48190.1 - 0.0065 15.7 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 CDJ48190.1 - 0.0065 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 CDJ48190.1 - 0.0083 15.6 0.1 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 CDJ48190.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 CDJ48190.1 - 0.011 16.2 0.8 0.032 14.6 0.8 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDJ48190.1 - 0.011 15.3 0.1 0.088 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDJ48190.1 - 0.013 15.7 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDJ48190.1 - 0.016 14.9 0.1 0.041 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ48190.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 CDJ48190.1 - 0.022 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 CDJ48190.1 - 0.029 14.8 0.0 0.048 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 CDJ48190.1 - 0.032 14.0 0.8 0.063 13.1 0.8 1.7 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 CDJ48190.1 - 0.036 13.2 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 CDJ48190.1 - 0.039 14.3 0.4 0.086 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain ADK PF00406.22 CDJ48190.1 - 0.059 13.5 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Adenylate kinase FapA PF03961.13 CDJ48191.1 - 0.31 9.6 3.5 0.48 9.0 3.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Serine_rich PF08824.10 CDJ48191.1 - 4.5 7.2 11.4 3.4 7.7 5.2 2.6 2 1 0 2 2 2 0 Serine rich protein interaction domain zf-AN1 PF01428.16 CDJ48192.1 - 0.00032 20.8 15.1 0.00055 20.0 15.1 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Shadoo PF14999.6 CDJ48192.1 - 0.0062 16.6 21.0 0.0062 16.6 21.0 5.1 2 1 2 4 4 4 1 Shadow of prion protein, neuroprotective DUF4746 PF15928.5 CDJ48193.1 - 0.0026 17.2 2.3 0.003 17.0 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 CDJ48193.1 - 0.01 15.6 3.5 0.013 15.3 3.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.18 CDJ48193.1 - 0.013 15.4 2.5 0.015 15.2 2.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.19 CDJ48193.1 - 0.017 15.7 11.4 0.027 15.1 11.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein FYDLN_acid PF09538.10 CDJ48193.1 - 0.023 15.3 2.9 0.038 14.7 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.14 CDJ48193.1 - 0.038 12.3 4.7 0.042 12.1 4.7 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 CDJ48193.1 - 0.21 11.2 6.0 0.33 10.6 6.0 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 CDJ48193.1 - 0.37 10.1 5.4 0.46 9.8 5.4 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 CDJ48193.1 - 0.57 8.2 6.3 0.62 8.1 6.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi RR_TM4-6 PF06459.12 CDJ48193.1 - 0.58 9.9 8.5 0.68 9.7 8.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 CDJ48193.1 - 0.74 9.6 3.9 0.89 9.3 3.9 1.1 1 0 0 1 1 1 0 AAA domain PBP1_TM PF14812.6 CDJ48193.1 - 3.6 8.0 9.4 6.1 7.3 9.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Apt1 PF10351.9 CDJ48194.1 - 3.8 6.3 7.9 5 5.9 7.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM60A PF15396.6 CDJ48195.1 - 0.33 10.9 31.5 0.42 10.6 31.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4207 PF13904.6 CDJ48196.1 - 0.084 12.5 3.8 0.11 12.2 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Ribosomal_L30_N PF08079.12 CDJ48196.1 - 0.21 11.9 21.1 0.11 12.7 16.4 2.0 1 1 1 2 2 2 0 Ribosomal L30 N-terminal domain RskA PF10099.9 CDJ48196.1 - 0.95 9.7 14.9 1.2 9.4 14.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TRM PF02005.16 CDJ48197.1 - 3.7e-50 171.2 0.0 4.4e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 CDJ48197.1 - 2 7.8 6.0 0.33 10.3 1.6 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Cellulose_synt PF03552.14 CDJ48198.1 - 0.15 10.5 3.9 0.23 9.9 3.9 1.3 1 0 0 1 1 1 0 Cellulose synthase DUF4235 PF14019.6 CDJ48198.1 - 2.5 8.2 23.9 0.099 12.7 3.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4235) SID-1_RNA_chan PF13965.6 CDJ48198.1 - 3.6 5.9 7.2 5.1 5.4 7.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Suf PF05843.14 CDJ48200.1 - 0.012 15.6 8.9 0.013 15.5 8.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med3 PF11593.8 CDJ48200.1 - 0.018 14.3 6.5 0.02 14.1 6.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAM199X PF15814.5 CDJ48200.1 - 0.025 13.7 11.0 0.029 13.4 11.0 1.0 1 0 0 1 1 1 0 Protein family FAM199X Pex14_N PF04695.13 CDJ48200.1 - 0.037 14.7 12.2 0.046 14.4 12.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 CDJ48200.1 - 0.084 12.7 10.7 0.094 12.5 10.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spt20 PF12090.8 CDJ48200.1 - 0.12 11.9 19.4 0.16 11.6 19.4 1.3 1 0 0 1 1 1 0 Spt20 family DUF5427 PF10310.9 CDJ48200.1 - 0.13 11.2 13.6 0.14 11.1 13.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CPSF100_C PF13299.6 CDJ48200.1 - 0.18 12.0 6.5 0.2 11.8 6.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 CDJ48200.1 - 0.18 10.7 8.8 0.2 10.6 8.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Baculo_PP31 PF05311.11 CDJ48200.1 - 0.22 11.0 7.6 0.24 10.8 7.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Velvet PF11754.8 CDJ48200.1 - 0.28 11.1 13.0 0.3 11.0 13.0 1.0 1 0 0 1 1 1 0 Velvet factor SMYLE_N PF18615.1 CDJ48200.1 - 0.3 10.6 12.3 0.32 10.5 12.3 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF4614 PF15391.6 CDJ48200.1 - 0.35 10.8 23.1 0.44 10.5 23.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) TFIIA PF03153.13 CDJ48200.1 - 0.38 10.7 19.1 0.45 10.5 19.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 CDJ48200.1 - 0.39 9.0 15.8 0.4 8.9 15.8 1.0 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 CDJ48200.1 - 0.47 9.2 17.5 0.59 8.9 17.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dsh_C PF12316.8 CDJ48200.1 - 0.62 10.4 20.4 0.76 10.1 20.4 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SOBP PF15279.6 CDJ48200.1 - 0.68 10.5 11.6 0.72 10.4 11.6 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein TCP PF03634.13 CDJ48200.1 - 0.74 10.4 19.3 0.94 10.0 19.3 1.2 1 0 0 1 1 1 0 TCP family transcription factor Ndc1_Nup PF09531.10 CDJ48200.1 - 0.96 8.1 8.5 1 7.9 8.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peroxin-3 PF04882.12 CDJ48200.1 - 0.98 8.3 13.9 1.1 8.2 13.9 1.0 1 0 0 1 1 1 0 Peroxin-3 Apt1 PF10351.9 CDJ48200.1 - 1.2 7.9 17.1 1.3 7.8 17.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop14 PF04147.12 CDJ48200.1 - 1.3 7.2 16.6 1.5 7.0 16.6 1.0 1 0 0 1 1 1 0 Nop14-like family Menin PF05053.13 CDJ48200.1 - 1.3 7.3 7.7 1.5 7.1 7.7 1.0 1 0 0 1 1 1 0 Menin EOS1 PF12326.8 CDJ48200.1 - 1.8 8.5 8.5 2.3 8.1 8.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein PI3K_1B_p101 PF10486.9 CDJ48200.1 - 1.9 6.1 15.1 2.2 6.0 15.1 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SR-25 PF10500.9 CDJ48200.1 - 2 8.0 34.0 3.7 7.1 34.0 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SelP_N PF04592.14 CDJ48200.1 - 2.2 7.7 15.1 2.7 7.3 15.1 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 CDJ48200.1 - 2.3 6.7 14.5 3 6.3 14.5 1.2 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 CDJ48200.1 - 2.5 7.2 12.4 2.9 7.0 12.4 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter MID_MedPIWI PF18296.1 CDJ48200.1 - 2.6 7.8 14.7 3.3 7.4 14.7 1.1 1 0 0 1 1 1 0 MID domain of medPIWI Raftlin PF15250.6 CDJ48200.1 - 2.7 6.6 13.5 2.8 6.6 13.5 1.0 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 CDJ48200.1 - 2.8 6.6 19.6 3.2 6.4 19.6 1.0 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ48200.1 - 3.2 7.8 11.0 3.3 7.7 11.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MCM_bind PF09739.9 CDJ48200.1 - 4.3 5.7 14.2 4.6 5.6 14.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor EFTUD2 PF16004.5 CDJ48200.1 - 4.6 7.8 14.8 6.1 7.4 14.8 1.2 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus GREB1 PF15782.5 CDJ48200.1 - 5.5 4.0 14.0 6.1 3.8 14.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DDHD PF02862.17 CDJ48200.1 - 5.6 7.1 13.3 7.6 6.6 13.3 1.2 1 0 0 1 1 1 0 DDHD domain Bul1_N PF04425.12 CDJ48200.1 - 6.8 5.3 12.6 8.1 5.1 12.6 1.0 1 0 0 1 1 1 0 Bul1 N terminus Ureide_permease PF07168.11 CDJ48200.1 - 8.8 5.0 5.8 9.8 4.8 5.8 1.0 1 0 0 1 1 1 0 Ureide permease CSG2 PF16965.5 CDJ48200.1 - 8.9 5.1 8.4 10 5.0 8.4 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator NPR3 PF03666.13 CDJ48201.1 - 0.05 12.4 3.0 0.055 12.3 3.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIA PF03153.13 CDJ48201.1 - 0.065 13.2 29.2 0.086 12.8 29.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0492 PF15744.5 CDJ48201.1 - 0.067 12.4 11.8 0.08 12.1 11.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Lin-8 PF03353.15 CDJ48201.1 - 0.081 12.5 7.6 0.087 12.4 7.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PIP5K PF01504.18 CDJ48201.1 - 0.11 11.7 4.1 0.13 11.4 4.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Connexin PF00029.19 CDJ48201.1 - 0.13 12.0 4.0 0.16 11.7 4.0 1.1 1 0 0 1 1 1 0 Connexin CPSF100_C PF13299.6 CDJ48201.1 - 0.15 12.3 6.2 0.2 11.8 6.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal eIF-3_zeta PF05091.12 CDJ48201.1 - 0.18 10.8 10.6 0.18 10.7 10.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.6 CDJ48201.1 - 0.2 11.6 3.9 0.24 11.4 3.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A S_layer_N PF05123.12 CDJ48201.1 - 0.22 11.3 3.9 0.28 11.0 3.9 1.3 1 0 0 1 1 1 0 S-layer like family, N-terminal region DUF913 PF06025.12 CDJ48201.1 - 0.35 9.8 4.0 0.4 9.6 4.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SARAF PF06682.12 CDJ48201.1 - 0.39 10.3 10.8 0.43 10.2 10.8 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Velvet PF11754.8 CDJ48201.1 - 0.53 10.2 9.2 0.65 9.9 9.2 1.1 1 0 0 1 1 1 0 Velvet factor LIM_bind PF01803.16 CDJ48201.1 - 0.55 9.7 6.6 0.66 9.5 6.6 1.1 1 0 0 1 1 1 0 LIM-domain binding protein DOR PF14839.6 CDJ48201.1 - 1.1 9.1 15.2 1.3 8.9 15.2 1.1 1 0 0 1 1 1 0 DOR family DUF1980 PF09323.10 CDJ48201.1 - 1.4 8.8 6.5 1.8 8.4 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DDHD PF02862.17 CDJ48201.1 - 1.4 9.0 7.6 1.7 8.8 7.6 1.2 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.7 CDJ48201.1 - 1.4 6.9 7.3 1.6 6.8 7.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 CDJ48201.1 - 1.6 8.5 10.6 1.8 8.3 10.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GET2 PF08690.10 CDJ48201.1 - 1.6 8.4 8.9 2.1 7.9 8.9 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Presenilin PF01080.17 CDJ48201.1 - 1.6 7.4 14.4 1.8 7.2 14.4 1.0 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 CDJ48201.1 - 1.7 7.4 5.5 1.9 7.3 5.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4228 PF14009.6 CDJ48201.1 - 1.7 9.0 6.8 2.3 8.6 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) PAT1 PF09770.9 CDJ48201.1 - 3.9 5.6 20.9 4 5.6 20.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ48201.1 - 4.1 7.4 5.5 4.6 7.2 5.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hydin_ADK PF17213.3 CDJ48201.1 - 4.1 7.6 13.3 5.7 7.2 13.3 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CLN3 PF02487.17 CDJ48201.1 - 5.5 5.9 5.0 6 5.8 5.0 1.1 1 0 0 1 1 1 0 CLN3 protein Med15 PF09606.10 CDJ48201.1 - 5.8 5.5 31.7 8.2 5.0 31.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal OmpH PF03938.14 CDJ48201.1 - 6 7.2 27.9 8.6 6.7 27.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Baculo_PP31 PF05311.11 CDJ48201.1 - 6.1 6.2 7.7 7.7 5.9 7.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Band_3_cyto PF07565.13 CDJ48201.1 - 6.7 6.4 9.6 8.3 6.1 9.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AAA_11 PF13086.6 CDJ48203.1 - 1.4e-59 202.0 0.7 2.8e-59 201.0 0.7 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 CDJ48203.1 - 9.5e-24 84.1 0.0 1.9e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ48203.1 - 2e-08 34.2 0.0 2e-08 34.2 0.0 4.4 4 1 1 5 5 4 2 AAA domain AAA_19 PF13245.6 CDJ48203.1 - 1.2e-07 32.2 0.0 7e-07 29.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ48203.1 - 0.00023 21.4 0.2 0.014 15.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 CDJ48203.1 - 0.0015 19.0 0.3 0.0078 16.6 0.0 2.4 2 1 1 3 3 2 1 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 CDJ48203.1 - 0.0017 18.3 0.5 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 Helicase DEAD PF00270.29 CDJ48203.1 - 0.002 17.9 0.1 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 CDJ48203.1 - 0.0025 17.4 0.2 0.0059 16.2 0.2 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 CDJ48203.1 - 0.0038 16.5 0.1 1.4 8.1 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) SR-25 PF10500.9 CDJ48203.1 - 0.0045 16.6 7.7 0.0045 16.6 7.7 2.4 1 1 1 2 2 1 1 Nuclear RNA-splicing-associated protein AAA_16 PF13191.6 CDJ48203.1 - 0.0063 16.9 0.6 0.0063 16.9 0.6 3.1 2 2 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 CDJ48203.1 - 0.011 15.5 0.1 0.54 9.9 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 CDJ48203.1 - 0.023 14.9 0.5 0.084 13.0 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CDJ48203.1 - 0.025 14.1 0.2 0.083 12.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain YscJ_FliF_C PF08345.11 CDJ48203.1 - 0.084 13.2 0.1 0.33 11.3 0.1 2.0 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal ResIII PF04851.15 CDJ48203.1 - 0.1 12.6 0.0 0.6 10.1 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Syntaxin-6_N PF09177.11 CDJ48203.1 - 0.11 13.1 2.4 0.15 12.6 0.7 2.1 2 0 0 2 2 1 0 Syntaxin 6, N-terminal DUF3446 PF11928.8 CDJ48203.1 - 0.15 12.4 8.3 0.3 11.4 2.1 3.5 2 0 0 2 2 2 0 Early growth response N-terminal domain PhoH PF02562.16 CDJ48203.1 - 0.16 11.4 0.1 0.57 9.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 CDJ48203.1 - 0.2 11.3 0.0 3.5 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CDJ48203.1 - 0.21 11.5 0.0 0.81 9.6 0.0 2.0 2 0 0 2 2 1 0 NTPase AAA_23 PF13476.6 CDJ48203.1 - 8.2 6.9 7.1 62 4.0 7.1 2.3 1 1 0 1 1 1 0 AAA domain TIM PF00121.18 CDJ48204.1 - 4.3e-30 104.9 0.0 5.6e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase CbiJ PF02571.14 CDJ48204.1 - 0.007 15.9 0.0 0.0095 15.4 0.0 1.3 1 1 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK RskA PF10099.9 CDJ48204.1 - 0.016 15.5 11.9 0.026 14.8 11.9 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA AAA_26 PF13500.6 CDJ48204.1 - 0.045 13.6 0.0 0.094 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain TFIIA PF03153.13 CDJ48204.1 - 0.16 11.9 2.5 0.15 12.0 2.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5542 PF17696.1 CDJ48204.1 - 0.34 11.1 2.8 0.86 9.8 2.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5542) Telomere_Sde2_2 PF13297.6 CDJ48205.1 - 0.046 13.4 0.1 0.15 11.7 0.1 1.8 1 0 0 1 1 1 0 Telomere stability C-terminal RPN2_C PF18004.1 CDJ48206.1 - 1.1 9.1 24.3 1.1 9.1 24.3 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ureide_permease PF07168.11 CDJ48206.1 - 4.3 6.0 14.8 4.2 6.0 14.8 1.0 1 0 0 1 1 1 0 Ureide permease Connexin PF00029.19 CDJ48206.1 - 7.2 6.3 24.0 7.4 6.3 24.0 1.1 1 0 0 1 1 1 0 Connexin Mitofilin PF09731.9 CDJ48207.1 - 5.5 5.7 27.8 7.7 5.2 27.8 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Bud13 PF09736.9 CDJ48208.1 - 1.3e-31 110.0 5.9 1.3e-31 110.0 5.9 3.2 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex AAA PF00004.29 CDJ48209.1 - 1.3e-38 132.4 0.0 2.9e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ48209.1 - 1.5e-09 37.5 0.1 3.1e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDJ48209.1 - 3.1e-06 27.7 5.3 0.0013 19.1 0.2 3.7 2 1 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 CDJ48209.1 - 0.00014 21.9 0.0 0.00057 19.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ48209.1 - 0.00034 20.9 0.3 0.06 13.6 0.1 3.0 1 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 CDJ48209.1 - 0.0025 18.0 0.0 0.0063 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 CDJ48209.1 - 0.0048 16.4 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 CDJ48209.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ48209.1 - 0.026 14.0 0.0 0.071 12.6 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CDJ48209.1 - 0.032 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 CDJ48209.1 - 0.033 13.4 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 CDJ48209.1 - 0.039 14.1 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CDJ48209.1 - 0.046 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CDJ48209.1 - 0.053 13.3 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CDJ48209.1 - 0.073 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CDJ48209.1 - 0.073 13.0 0.1 0.18 11.7 0.1 1.7 1 1 0 1 1 1 0 NACHT domain TsaE PF02367.17 CDJ48209.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HDPD PF02924.14 CDJ48210.1 - 0.08 13.0 1.5 14 5.8 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D PRIMA1 PF16101.5 CDJ48210.1 - 0.9 9.6 5.5 0.18 11.8 0.2 2.4 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 DDOST_48kD PF03345.14 CDJ48211.1 - 4.7e-40 137.7 0.0 6.1e-37 127.4 0.0 2.2 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta 2OG-FeII_Oxy_3 PF13640.6 CDJ48211.1 - 5.3e-05 24.0 0.0 0.00019 22.2 0.0 2.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 CDJ48211.1 - 0.0034 16.5 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Poxvirus C4/C10 protein TPR_14 PF13428.6 CDJ48211.1 - 0.77 10.7 4.5 1.3 10.0 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat NT-C2 PF10358.9 CDJ48212.1 - 0.00048 19.9 0.0 0.0095 15.7 0.0 2.5 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Dehydrin PF00257.19 CDJ48214.1 - 0.024 15.2 13.4 0.032 14.8 13.4 1.2 1 0 0 1 1 1 0 Dehydrin RskA PF10099.9 CDJ48214.1 - 0.039 14.2 26.4 0.057 13.7 26.4 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ48214.1 - 0.1 12.2 17.0 0.11 12.0 17.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FHIPEP PF00771.20 CDJ48214.1 - 0.31 9.4 3.7 0.32 9.4 3.7 1.0 1 0 0 1 1 1 0 FHIPEP family DUF4813 PF16072.5 CDJ48214.1 - 0.55 9.8 18.7 0.7 9.5 18.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) IHABP4_N PF16174.5 CDJ48214.1 - 1.1 9.8 14.9 1.3 9.6 14.9 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF3138 PF11336.8 CDJ48214.1 - 1.2 7.7 19.3 1.2 7.7 19.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2572 PF10833.8 CDJ48214.1 - 1.5 8.6 5.8 1.7 8.4 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) DUF3450 PF11932.8 CDJ48214.1 - 1.7 7.9 16.2 2 7.6 16.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) R_equi_Vir PF05526.11 CDJ48214.1 - 2.7 7.8 9.0 3.1 7.6 9.0 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Paf1 PF03985.13 CDJ48214.1 - 3.1 6.7 10.7 3.1 6.7 10.7 1.0 1 0 0 1 1 1 0 Paf1 BAF1_ABF1 PF04684.13 CDJ48214.1 - 4.6 6.2 14.8 5.5 5.9 14.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CPSF100_C PF13299.6 CDJ48214.1 - 8.1 6.6 10.1 8.5 6.5 10.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PepSY_TM PF03929.16 CDJ48214.1 - 9.8 5.7 6.6 10 5.7 6.6 1.1 1 0 0 1 1 1 0 PepSY-associated TM region SNF2_N PF00176.23 CDJ48215.1 - 2.6e-08 33.0 16.8 2.6e-08 33.0 16.8 2.7 2 1 0 2 2 2 1 SNF2 family N-terminal domain BUD22 PF09073.10 CDJ48215.1 - 0.00016 21.2 14.6 0.00016 21.2 14.6 5.0 3 2 1 4 4 4 1 BUD22 TAF4 PF05236.14 CDJ48215.1 - 0.00061 19.6 14.0 0.00061 19.6 14.0 7.7 4 2 4 8 8 8 1 Transcription initiation factor TFIID component TAF4 family SPX PF03105.19 CDJ48215.1 - 0.00064 19.8 23.1 0.00064 19.8 23.1 5.4 3 1 0 4 4 4 1 SPX domain DUF1645 PF07816.11 CDJ48215.1 - 0.015 15.9 12.2 0.015 15.9 12.2 9.5 6 2 2 8 8 8 0 Protein of unknown function (DUF1645) eIF-3_zeta PF05091.12 CDJ48215.1 - 1.2 8.1 58.9 0.31 10.0 27.4 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CtsR PF05848.11 CDJ48217.1 - 0.2 11.6 4.9 19 5.3 0.1 3.7 2 1 2 4 4 4 0 CtsR N-terminal HTH domain DUF4605 PF15378.6 CDJ48217.1 - 0.61 10.0 3.7 20 5.1 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4605) AHJR-like PF18743.1 CDJ48218.1 - 0.057 13.0 0.4 1.1 8.9 0.2 2.3 1 1 1 2 2 2 0 REase_AHJR-like Sec16 PF12932.7 CDJ48219.1 - 1.3 9.7 10.8 0.53 10.9 1.4 4.2 3 1 0 3 3 3 0 Vesicle coat trafficking protein Sec16 mid-region RskA PF10099.9 CDJ48220.1 - 0.00061 20.1 15.0 0.00061 20.1 15.0 3.2 2 1 0 3 3 3 1 Anti-sigma-K factor rskA DUF2368 PF10166.9 CDJ48220.1 - 0.023 14.3 1.4 0.023 14.3 1.4 3.6 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2368) Pinin_SDK_memA PF04696.13 CDJ48220.1 - 5 7.2 36.2 0.44 10.6 7.8 3.3 3 0 0 3 3 3 0 pinin/SDK/memA/ protein conserved region Hamartin PF04388.12 CDJ48222.1 - 0.0028 16.4 17.1 0.0032 16.2 17.1 1.2 1 0 0 1 1 1 1 Hamartin protein Med15 PF09606.10 CDJ48222.1 - 0.017 13.8 68.6 0.021 13.5 68.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Exonuc_VII_L PF02601.15 CDJ48222.1 - 0.023 14.3 33.7 0.029 13.9 33.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.9 CDJ48222.1 - 0.038 12.3 48.8 0.043 12.1 48.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF726 PF05277.12 CDJ48222.1 - 0.061 12.3 3.6 0.078 11.9 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) RR_TM4-6 PF06459.12 CDJ48222.1 - 0.21 11.4 26.8 0.26 11.1 26.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF572 PF04502.13 CDJ48222.1 - 0.35 10.5 22.8 0.42 10.2 22.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAM222A PF15258.6 CDJ48222.1 - 0.36 9.9 46.5 0.49 9.5 46.5 1.3 1 0 0 1 1 1 0 Protein family of FAM222A RIFIN PF02009.16 CDJ48222.1 - 0.43 10.4 26.7 0.64 9.8 26.7 1.2 1 0 0 1 1 1 0 Rifin FapA PF03961.13 CDJ48222.1 - 0.46 9.0 20.8 0.57 8.7 20.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Nop53 PF07767.11 CDJ48222.1 - 0.52 9.6 36.3 0.69 9.2 36.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Miga PF10265.9 CDJ48222.1 - 0.82 8.6 19.2 1.1 8.2 19.2 1.1 1 0 0 1 1 1 0 Mitoguardin Caldesmon PF02029.15 CDJ48222.1 - 0.9 8.2 30.6 1.1 7.9 30.6 1.1 1 0 0 1 1 1 0 Caldesmon DUF4045 PF13254.6 CDJ48222.1 - 0.92 9.1 24.3 1.2 8.7 24.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SID-1_RNA_chan PF13965.6 CDJ48222.1 - 1.2 7.5 12.3 1.6 7.1 12.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PA26 PF04636.13 CDJ48222.1 - 1.3 7.8 23.2 1.7 7.5 23.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GREB1 PF15782.5 CDJ48222.1 - 1.4 6.0 31.8 1.6 5.7 31.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GAGA_bind PF06217.12 CDJ48222.1 - 1.4 9.1 23.4 1.8 8.7 23.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.17 CDJ48222.1 - 1.6 7.4 37.0 2.1 7.0 37.0 1.1 1 0 0 1 1 1 0 Presenilin Cellulose_synt PF03552.14 CDJ48222.1 - 2.9 6.3 10.4 3.8 5.9 10.4 1.2 1 0 0 1 1 1 0 Cellulose synthase CDC45 PF02724.14 CDJ48222.1 - 3.1 6.0 28.3 4 5.6 28.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Radical_SAM_N PF08497.10 CDJ48222.1 - 4.4 6.5 16.6 6.1 6.0 16.6 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal Tyrosinase PF00264.20 CDJ48222.1 - 4.6 7.5 17.0 6.7 6.9 17.0 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase FAM60A PF15396.6 CDJ48222.1 - 5.2 7.0 25.2 7.4 6.5 25.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Smg8_Smg9 PF10220.9 CDJ48222.1 - 6.8 4.9 29.7 8.1 4.6 29.7 1.0 1 0 0 1 1 1 0 Smg8_Smg9 CCSAP PF15748.5 CDJ48222.1 - 7.9 6.6 34.3 11 6.1 34.3 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Draxin PF15550.6 CDJ48222.1 - 8.8 6.1 20.7 11 5.7 20.7 1.2 1 0 0 1 1 1 0 Draxin V_ATPase_I PF01496.19 CDJ48222.1 - 9.7 4.0 30.4 12 3.6 30.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family tRNA-synt_2 PF00152.20 CDJ48223.1 - 2.2e-33 115.7 0.1 7.5e-33 113.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF2722 PF10846.8 CDJ48223.1 - 3.9e-06 26.1 4.4 3.9e-06 26.1 4.4 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF2722) Apt1 PF10351.9 CDJ48223.1 - 0.00028 19.9 21.7 0.17 10.7 0.0 3.4 2 2 0 3 3 3 2 Golgi-body localisation protein domain DUF3299 PF11736.8 CDJ48223.1 - 0.0016 18.5 2.2 0.0035 17.4 2.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3299) Spt20 PF12090.8 CDJ48223.1 - 0.0031 17.2 13.8 0.0031 17.2 13.8 3.0 3 1 0 3 3 3 1 Spt20 family tRNA_anti-codon PF01336.25 CDJ48223.1 - 0.0039 17.2 0.0 0.007 16.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Tnp_DNA_bind PF14706.6 CDJ48223.1 - 0.13 12.1 0.2 0.13 12.1 0.2 3.4 4 0 0 4 4 4 0 Transposase DNA-binding TFIIA PF03153.13 CDJ48223.1 - 1.5 8.7 36.1 14 5.5 23.6 2.4 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit RLL PF10036.9 CDJ48223.1 - 3 7.6 10.4 0.2 11.4 3.9 2.3 3 0 0 3 3 3 0 RNA transcription, translation and transport factor protein Secretin_N_2 PF07655.13 CDJ48223.1 - 9.6 6.8 76.0 1.2 9.7 17.2 6.1 6 0 0 6 6 6 0 Secretin N-terminal domain Hydrolase_4 PF12146.8 CDJ48224.1 - 2.1e-17 63.2 4.8 9.2e-06 25.1 0.1 4.8 3 1 1 4 4 4 3 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ48224.1 - 0.0014 18.4 0.0 0.024 14.3 0.0 3.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold SUIM_assoc PF16619.5 CDJ48224.1 - 0.0097 16.0 46.4 0.012 15.7 1.5 4.1 4 0 0 4 4 3 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ48224.1 - 0.043 13.4 38.4 0.099 12.2 8.3 3.5 3 0 0 3 3 3 0 Spt20 family DUF2722 PF10846.8 CDJ48224.1 - 0.09 11.7 22.0 0.057 12.4 1.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) PPP4R2 PF09184.11 CDJ48224.1 - 0.096 12.3 3.0 0.21 11.1 3.0 1.5 1 0 0 1 1 1 0 PPP4R2 UPF0227 PF05728.12 CDJ48224.1 - 0.27 11.1 0.0 0.27 11.1 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0227) GN3L_Grn1 PF08701.11 CDJ48224.1 - 0.32 11.1 20.8 0.083 13.0 2.0 2.8 3 0 0 3 3 2 0 GNL3L/Grn1 putative GTPase AP3D1 PF06375.11 CDJ48224.1 - 0.34 11.2 9.4 0.2 11.9 1.0 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 EPL1 PF10513.9 CDJ48224.1 - 3.6 7.9 12.4 1.5 9.2 0.5 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like Mak16 PF04874.14 CDJ48224.1 - 7.9 7.2 13.3 17 6.1 3.2 3.1 3 0 0 3 3 3 0 Mak16 protein C-terminal region IER PF05760.12 CDJ48225.1 - 0.0063 16.9 19.8 0.0077 16.6 19.8 1.1 1 0 0 1 1 1 1 Immediate early response protein (IER) Presenilin PF01080.17 CDJ48225.1 - 0.022 13.5 20.9 0.028 13.2 20.9 1.2 1 0 0 1 1 1 0 Presenilin LTV PF04180.14 CDJ48225.1 - 0.11 12.2 17.4 0.16 11.7 17.4 1.1 1 0 0 1 1 1 0 Low temperature viability protein SOG2 PF10428.9 CDJ48225.1 - 0.17 11.1 16.9 0.19 10.9 16.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Lin-8 PF03353.15 CDJ48225.1 - 0.23 11.0 27.2 0.34 10.4 27.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 CDJ48225.1 - 0.26 9.5 20.8 0.36 9.1 20.8 1.1 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 CDJ48225.1 - 0.3 8.2 26.0 0.35 7.9 26.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SPX PF03105.19 CDJ48225.1 - 0.4 10.6 23.7 0.51 10.2 23.7 1.1 1 0 0 1 1 1 0 SPX domain Pkinase_fungal PF17667.1 CDJ48225.1 - 0.47 9.2 6.0 0.52 9.0 6.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CENP-N PF05238.13 CDJ48225.1 - 0.53 9.5 16.0 0.77 9.0 16.0 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like SRP-alpha_N PF04086.13 CDJ48225.1 - 2 8.3 25.3 2.7 7.8 25.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PAT1 PF09770.9 CDJ48225.1 - 2 6.6 38.5 2.4 6.3 38.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.12 CDJ48225.1 - 2.5 8.3 18.3 7.4 6.8 18.9 1.5 2 0 0 2 2 2 0 GAGA binding protein-like family SLC12 PF03522.15 CDJ48225.1 - 3.4 6.6 20.7 4.3 6.3 20.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Asp-B-Hydro_N PF05279.11 CDJ48225.1 - 4.3 7.3 19.1 7.6 6.5 19.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PP2C PF00481.21 CDJ48226.1 - 8.1e-20 71.5 0.2 8.1e-20 71.5 0.2 2.0 1 1 1 2 2 2 1 Protein phosphatase 2C Macoilin PF09726.9 CDJ48226.1 - 1.5e-05 23.8 24.8 1.7e-05 23.7 24.8 1.0 1 0 0 1 1 1 1 Macoilin family TFIIA PF03153.13 CDJ48226.1 - 0.003 17.6 27.5 0.0037 17.3 27.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit UMP1 PF05348.11 CDJ48226.1 - 0.028 14.6 6.9 0.062 13.5 6.9 1.5 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 SLC12 PF03522.15 CDJ48226.1 - 0.096 11.7 26.0 0.14 11.1 26.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PI3K_1B_p101 PF10486.9 CDJ48226.1 - 0.11 10.3 22.7 0.13 10.1 22.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit WDCP PF15390.6 CDJ48226.1 - 0.14 10.5 21.2 0.16 10.3 21.2 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PAP1 PF08601.10 CDJ48226.1 - 0.22 11.2 34.6 0.28 10.9 34.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Spc7_N PF15402.6 CDJ48226.1 - 0.23 9.6 38.8 0.3 9.3 38.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 baeRF_family10 PF18854.1 CDJ48226.1 - 0.35 11.1 7.0 80 3.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 DUF572 PF04502.13 CDJ48226.1 - 0.42 10.2 26.0 0.61 9.7 26.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Draxin PF15550.6 CDJ48226.1 - 0.57 10.0 21.9 0.81 9.5 21.9 1.2 1 0 0 1 1 1 0 Draxin TFIIF_alpha PF05793.12 CDJ48226.1 - 0.85 8.1 29.9 1.1 7.8 29.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SOG2 PF10428.9 CDJ48226.1 - 1.6 7.9 34.1 2.1 7.5 34.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CDK5_activator PF03261.15 CDJ48226.1 - 1.8 8.0 22.9 2.3 7.7 22.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Ndc1_Nup PF09531.10 CDJ48226.1 - 2.6 6.6 27.4 3.4 6.2 27.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PNISR PF15996.5 CDJ48226.1 - 2.7 8.2 29.6 4.8 7.4 29.6 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF4647 PF15504.6 CDJ48226.1 - 7.3 5.6 27.3 9.9 5.1 27.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Mitofilin PF09731.9 CDJ48226.1 - 8.7 5.1 26.4 12 4.6 26.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Utp14 PF04615.13 CDJ48226.1 - 9.4 4.7 33.3 12 4.3 33.3 1.0 1 0 0 1 1 1 0 Utp14 protein PP2C PF00481.21 CDJ48227.1 - 1.8e-16 60.6 0.0 2.1e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ48227.1 - 0.00029 20.8 0.0 0.00034 20.6 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) CHDNT PF08073.12 CDJ48227.1 - 0.02 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain DUF2722 PF10846.8 CDJ48228.1 - 0.0021 17.1 2.9 0.0071 15.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) RNA_polI_A34 PF08208.11 CDJ48228.1 - 0.0052 16.9 1.5 0.0052 16.9 1.5 1.6 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Ribosomal_L37e PF01907.19 CDJ48229.1 - 0.0028 17.8 0.4 0.0062 16.7 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DUF2722 PF10846.8 CDJ48229.1 - 0.0036 16.3 1.4 0.0036 16.3 1.4 9.0 9 2 1 10 10 10 3 Protein of unknown function (DUF2722) Lactamase_B_2 PF12706.7 CDJ48229.1 - 0.01 15.4 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain HEAT PF02985.22 CDJ48229.1 - 0.025 14.8 1.4 0.15 12.4 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat Cohesin_HEAT PF12765.7 CDJ48229.1 - 0.069 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion E6 PF00518.17 CDJ48229.1 - 2.4 8.6 11.4 0.23 11.9 1.1 3.0 2 0 0 2 2 2 0 Early Protein (E6) ADIP PF11559.8 CDJ48231.1 - 0.0012 19.0 16.9 0.0012 19.0 16.9 5.1 4 1 1 5 5 5 1 Afadin- and alpha -actinin-Binding TCP PF03634.13 CDJ48231.1 - 0.0026 18.3 9.0 0.0026 18.3 9.0 5.3 3 1 2 5 5 5 2 TCP family transcription factor Merozoite_SPAM PF07133.11 CDJ48232.1 - 0.36 10.8 45.7 0.48 10.4 45.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Trypan_PARP PF05887.11 CDJ48232.1 - 2.9 7.9 33.1 0.7 9.9 29.8 1.7 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 CDJ48232.1 - 6.2 6.4 38.4 4.2e+02 0.3 38.4 2.0 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Leo1 PF04004.13 CDJ48233.1 - 0.00013 21.9 0.1 0.00047 20.1 0.0 2.0 1 1 1 2 2 2 1 Leo1-like protein SUIM_assoc PF16619.5 CDJ48233.1 - 0.011 15.8 0.9 0.021 14.9 0.9 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 AAA_23 PF13476.6 CDJ48234.1 - 0.01 16.3 24.0 0.016 15.7 24.0 1.2 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.9 CDJ48234.1 - 0.5 9.9 75.9 0.23 11.1 28.8 3.0 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ48234.1 - 6.2 7.2 30.2 0.52 10.6 5.4 2.8 2 0 0 2 2 2 0 Early growth response N-terminal domain Cofac_haem_bdg PF04187.13 CDJ48235.1 - 0.021 14.8 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN RVP_2 PF08284.11 CDJ48236.1 - 4.6e-09 36.1 0.0 8.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ48236.1 - 2.4e-05 24.8 0.0 8.5e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ48236.1 - 4.1e-05 24.2 0.0 9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ48236.1 - 0.035 14.4 0.0 0.094 13.0 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ48236.1 - 0.11 12.3 0.0 0.63 9.8 0.0 2.0 1 1 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 CDJ48237.1 - 4.8e-14 52.4 0.0 8.9e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ48237.1 - 1.3e-09 38.0 0.1 2.8e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ48237.1 - 1.5e-07 31.7 0.0 3.2e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Integrase core domain DUF2722 PF10846.8 CDJ48238.1 - 0.022 13.7 56.1 0.016 14.2 17.6 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) Herpes_LMP1 PF05297.11 CDJ48238.1 - 0.29 10.3 0.3 0.7 9.0 0.3 1.6 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SID-1_RNA_chan PF13965.6 CDJ48238.1 - 0.39 9.1 0.3 14 4.0 0.1 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 MecA PF05389.12 CDJ48238.1 - 0.71 9.5 11.7 0.17 11.5 0.2 3.3 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) Afi1 PF07792.12 CDJ48238.1 - 1.1 9.7 16.4 1.4 9.4 0.5 3.2 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ctr PF04145.15 CDJ48238.1 - 1.3 9.6 11.5 6.8 7.3 1.1 3.4 3 0 0 3 3 3 0 Ctr copper transporter family Connexin PF00029.19 CDJ48238.1 - 2.1 8.0 14.2 0.91 9.2 1.4 3.3 3 0 0 3 3 3 0 Connexin DUF2828 PF11443.8 CDJ48238.1 - 3.3 5.7 17.9 0.11 10.5 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Band_3_cyto PF07565.13 CDJ48238.1 - 5.5 6.7 20.6 1.4 8.7 4.5 3.3 3 0 0 3 3 3 0 Band 3 cytoplasmic domain TolA_bind_tri PF16331.5 CDJ48239.1 - 0.0027 17.7 0.7 0.0027 17.7 0.7 2.3 2 0 0 2 2 2 1 TolA binding protein trimerisation DUF2408 PF10303.9 CDJ48239.1 - 0.012 16.2 2.3 0.19 12.3 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) SKA2 PF16740.5 CDJ48239.1 - 0.022 14.5 2.6 0.66 9.8 0.5 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Seryl_tRNA_N PF02403.22 CDJ48239.1 - 0.046 14.0 2.8 0.075 13.3 2.8 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RskA PF10099.9 CDJ48239.1 - 0.26 11.5 44.4 1 9.6 15.0 3.3 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Csm2_III-A PF03750.13 CDJ48239.1 - 0.29 12.0 3.3 0.98 10.3 3.3 1.7 1 1 0 1 1 1 0 Csm2 Type III-A FlxA PF14282.6 CDJ48239.1 - 0.31 11.0 8.7 3 7.9 2.8 2.3 2 0 0 2 2 2 0 FlxA-like protein DivIC PF04977.15 CDJ48239.1 - 4.9 7.0 9.1 1.4 8.7 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator Trp_oprn_chp PF09534.10 CDJ48240.1 - 0.052 13.3 56.1 0.057 13.2 56.1 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Macoilin PF09726.9 CDJ48241.1 - 0.12 10.9 54.7 0.17 10.4 54.7 1.2 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 CDJ48241.1 - 0.29 9.4 12.4 0.36 9.1 12.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.9 CDJ48241.1 - 0.4 8.9 69.4 0.49 8.6 69.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.15 CDJ48241.1 - 2.9 7.4 52.5 5.1 6.6 52.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5585 PF17823.1 CDJ48241.1 - 3.1 6.6 32.3 3.7 6.4 32.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Caldesmon PF02029.15 CDJ48241.1 - 8.4 5.0 50.1 12 4.5 50.1 1.3 1 0 0 1 1 1 0 Caldesmon zf-CCHC PF00098.23 CDJ48243.1 - 2.9e-09 36.6 4.2 1.4e-05 24.9 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CDJ48243.1 - 0.023 15.1 2.3 0.044 14.2 2.3 1.4 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_5 PF14787.6 CDJ48243.1 - 0.032 14.0 2.1 1.9 8.3 0.6 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Cofac_haem_bdg PF04187.13 CDJ48243.1 - 0.17 11.8 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Spt20 PF12090.8 CDJ48245.1 - 0.013 15.1 17.7 0.014 15.0 17.7 1.1 1 0 0 1 1 1 0 Spt20 family SRP-alpha_N PF04086.13 CDJ48245.1 - 0.076 12.9 9.5 0.086 12.8 9.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal tRNA_synt_1c_R2 PF04557.15 CDJ48245.1 - 0.094 13.6 6.1 0.12 13.4 6.1 1.1 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 TFIIA PF03153.13 CDJ48245.1 - 0.13 12.2 14.5 0.15 12.1 14.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4770 PF15994.5 CDJ48245.1 - 0.15 12.3 6.9 0.18 12.0 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) TERB2 PF15101.6 CDJ48245.1 - 0.2 11.7 8.9 0.21 11.6 8.9 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2722 PF10846.8 CDJ48245.1 - 0.33 9.9 15.9 0.39 9.6 15.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF853 PF05872.12 CDJ48245.1 - 0.52 8.8 4.9 0.56 8.7 4.9 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Neur_chan_memb PF02932.16 CDJ48245.1 - 1 9.4 5.7 1.1 9.3 5.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Androgen_recep PF02166.16 CDJ48245.1 - 1.3 7.8 14.3 1.3 7.8 14.3 1.0 1 0 0 1 1 1 0 Androgen receptor DivIC PF04977.15 CDJ48245.1 - 1.5 8.6 9.3 11 5.9 9.7 1.9 2 0 0 2 2 2 0 Septum formation initiator CLN3 PF02487.17 CDJ48245.1 - 1.5 7.7 4.4 1.5 7.7 4.4 1.0 1 0 0 1 1 1 0 CLN3 protein FancD2 PF14631.6 CDJ48245.1 - 1.7 5.9 5.8 1.9 5.8 5.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF5345 PF17280.2 CDJ48245.1 - 1.9 8.5 8.5 11 6.0 6.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5345) UPF0560 PF10577.9 CDJ48245.1 - 2.1 6.7 10.3 2.5 6.5 10.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Band_3_cyto PF07565.13 CDJ48245.1 - 3 7.6 6.9 3.2 7.5 6.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4175 PF13779.6 CDJ48245.1 - 5.9 4.7 16.9 6.7 4.5 16.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Connexin PF00029.19 CDJ48245.1 - 7.4 6.3 6.8 8.2 6.1 6.8 1.2 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ48245.1 - 8.1 5.1 12.2 8.6 5.0 12.2 1.0 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 CDJ48248.1 - 4.6e-06 27.0 15.8 4.6e-06 27.0 15.8 2.2 1 1 1 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ48248.1 - 0.00013 22.1 26.2 0.00016 21.8 26.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TENA_THI-4 PF03070.16 CDJ48248.1 - 0.012 15.4 5.1 0.018 14.9 5.1 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family FHIPEP PF00771.20 CDJ48248.1 - 0.021 13.3 3.4 0.026 13.0 3.4 1.2 1 0 0 1 1 1 0 FHIPEP family Presenilin PF01080.17 CDJ48248.1 - 0.026 13.3 5.6 0.032 13.0 5.6 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CDJ48248.1 - 0.034 14.1 9.8 0.044 13.8 9.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ48248.1 - 0.04 13.5 28.3 0.067 12.8 28.3 1.3 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 CDJ48248.1 - 0.042 12.8 5.7 0.045 12.7 5.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) tRNA-synt_1c PF00749.21 CDJ48248.1 - 0.11 11.4 1.7 0.15 10.9 1.7 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain CLN3 PF02487.17 CDJ48248.1 - 0.16 11.0 1.8 0.18 10.8 1.8 1.2 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 CDJ48248.1 - 0.18 11.8 4.3 0.2 11.7 4.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ48248.1 - 0.35 10.6 5.9 0.62 9.8 5.9 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Serinc PF03348.15 CDJ48248.1 - 0.5 9.2 2.6 0.61 9.0 2.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) NEMP PF10225.9 CDJ48248.1 - 0.82 9.3 3.9 1.1 8.9 3.9 1.2 1 0 0 1 1 1 0 NEMP family DUF3464 PF11947.8 CDJ48248.1 - 0.96 9.2 6.3 0.23 11.2 2.4 1.9 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 G0-G1_switch_2 PF15103.6 CDJ48248.1 - 2 8.9 7.7 0.48 10.9 4.2 1.8 2 0 0 2 2 2 0 G0/G1 switch protein 2 PAT1 PF09770.9 CDJ48248.1 - 2 6.6 18.7 2.5 6.3 18.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATP11 PF06644.11 CDJ48248.1 - 8 6.2 14.5 14 5.4 14.5 1.5 1 1 0 1 1 1 0 ATP11 protein Hydin_ADK PF17213.3 CDJ48248.1 - 8.4 6.6 15.8 17 5.6 15.8 1.5 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain RskA PF10099.9 CDJ48249.1 - 0.19 12.0 18.7 0.27 11.5 18.7 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Aminotran_1_2 PF00155.21 CDJ48249.1 - 0.39 9.8 5.6 0.095 11.9 2.1 1.6 1 1 1 2 2 2 0 Aminotransferase class I and II Miga PF10265.9 CDJ48249.1 - 4.9 6.0 13.6 5.1 6.0 13.6 1.0 1 0 0 1 1 1 0 Mitoguardin RAP1 PF07218.11 CDJ48249.1 - 5.3 5.2 20.0 6.2 5.0 20.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SprA-related PF12118.8 CDJ48251.1 - 0.0094 15.1 33.1 0.012 14.8 33.1 1.1 1 0 0 1 1 1 1 SprA-related family TFIIA PF03153.13 CDJ48251.1 - 0.022 14.8 44.1 0.026 14.5 44.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ48251.1 - 0.097 11.6 15.9 0.11 11.4 15.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ48251.1 - 0.14 10.9 17.6 0.17 10.6 17.6 1.2 1 0 0 1 1 1 0 Presenilin DUF2126 PF09899.9 CDJ48251.1 - 0.16 10.0 7.2 0.21 9.6 7.2 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PAT1 PF09770.9 CDJ48251.1 - 0.25 9.6 29.3 0.26 9.5 29.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Connexin PF00029.19 CDJ48251.1 - 0.25 11.1 6.9 0.3 10.8 6.9 1.3 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 CDJ48251.1 - 0.46 8.8 2.8 0.48 8.8 2.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RIFIN PF02009.16 CDJ48251.1 - 0.47 10.3 12.6 0.61 9.9 12.6 1.1 1 0 0 1 1 1 0 Rifin DUF1387 PF07139.11 CDJ48251.1 - 0.51 10.0 18.8 0.67 9.6 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CDC45 PF02724.14 CDJ48251.1 - 0.65 8.2 11.3 0.75 8.0 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Med15 PF09606.10 CDJ48251.1 - 0.69 8.5 40.6 0.8 8.3 40.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Zip PF02535.22 CDJ48251.1 - 1.1 8.5 6.3 1.2 8.2 6.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 CDJ48251.1 - 1.2 8.1 14.3 1.4 7.9 14.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF3408 PF11888.8 CDJ48251.1 - 1.3 9.1 15.6 0.73 10.0 12.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) ALMT PF11744.8 CDJ48251.1 - 1.8 7.3 9.9 2.1 7.1 9.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4175 PF13779.6 CDJ48251.1 - 3.6 5.4 34.4 4.3 5.1 34.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Hid1 PF12722.7 CDJ48251.1 - 6.2 4.8 19.7 7.8 4.5 19.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CSG2 PF16965.5 CDJ48251.1 - 7 5.5 5.8 8.2 5.2 5.8 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator V_ATPase_I PF01496.19 CDJ48251.1 - 7.3 4.4 14.8 8.4 4.2 14.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tim54 PF11711.8 CDJ48251.1 - 7.8 5.2 17.7 1.7 7.3 14.3 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Membralin PF09746.9 CDJ48251.1 - 8.3 5.3 7.7 9.6 5.1 7.7 1.2 1 0 0 1 1 1 0 Tumour-associated protein PHC2_SAM_assoc PF16616.5 CDJ48252.1 - 0.021 15.6 0.0 0.021 15.6 0.0 3.0 3 0 0 3 3 3 0 Unstructured region on Polyhomeotic-like protein 1 and 2 RskA PF10099.9 CDJ48253.1 - 8.6e-05 22.9 5.0 8.6e-05 22.9 5.0 3.2 2 1 1 3 3 3 1 Anti-sigma-K factor rskA DUF5423 PF17461.2 CDJ48253.1 - 0.04 12.8 5.8 0.56 9.0 2.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5423) DUF4770 PF15994.5 CDJ48253.1 - 0.19 11.9 15.2 2.7 8.2 9.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Peptidase_S49_N PF08496.10 CDJ48253.1 - 0.93 9.6 12.1 3.5 7.7 7.4 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal BSP_II PF05432.11 CDJ48253.1 - 4 7.1 13.9 1.5 8.5 11.2 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Exo_endo_phos PF03372.23 CDJ48254.1 - 5.9e-06 26.0 0.0 7.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TFIIS_C PF01096.18 CDJ48255.1 - 9.6e-15 54.2 3.5 9.6e-15 54.2 3.5 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 CDJ48255.1 - 0.15 12.2 13.6 1.3 9.2 0.2 4.4 3 1 0 3 3 3 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 CDJ48255.1 - 0.23 11.2 0.1 0.23 11.2 0.1 3.9 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 CDJ48255.1 - 1.2 9.1 10.4 2.1 8.3 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 CDJ48255.1 - 2.4 8.0 11.8 32 4.4 0.2 4.2 4 0 0 4 4 4 0 zinc-ribbon domain KLRAQ PF10205.9 CDJ48256.1 - 0.00064 19.9 2.6 0.00084 19.5 2.6 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.11 CDJ48256.1 - 0.011 16.1 1.5 0.053 13.9 0.8 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 CDJ48256.1 - 0.023 15.1 1.8 0.031 14.7 1.8 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) GIT_CC PF16559.5 CDJ48256.1 - 0.029 14.2 5.3 0.051 13.5 5.3 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 CDJ48256.1 - 0.044 13.9 1.7 0.06 13.5 1.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4763 PF15960.5 CDJ48256.1 - 0.055 12.8 2.6 0.068 12.5 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) YabA PF06156.13 CDJ48256.1 - 0.077 13.6 1.3 0.11 13.1 1.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 CDJ48256.1 - 0.28 11.6 6.6 0.24 11.9 5.3 1.5 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 CDJ48256.1 - 6.1 6.7 7.3 6.9 6.5 3.1 2.4 1 1 1 2 2 2 0 Septum formation initiator Kelch_4 PF13418.6 CDJ48257.1 - 1.3e-11 44.3 1.7 4.1e-06 26.7 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ48257.1 - 3.9e-09 36.3 0.3 0.011 15.7 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 CDJ48257.1 - 6.9e-08 31.9 0.0 7.8e-06 25.4 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CDJ48257.1 - 9.4e-08 32.1 0.0 0.0003 20.9 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 CDJ48257.1 - 4.1e-07 30.1 3.0 0.00072 19.8 0.0 4.1 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ48257.1 - 5.6e-07 29.3 0.0 0.0047 16.8 0.0 3.1 2 0 0 2 2 2 2 Kelch motif SR-25 PF10500.9 CDJ48257.1 - 0.00026 20.7 19.5 0.0004 20.1 19.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Corona_nucleoca PF00937.18 CDJ48257.1 - 0.13 11.2 10.2 0.2 10.7 10.2 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein AC_N PF16214.5 CDJ48257.1 - 0.45 9.6 6.6 0.6 9.2 6.6 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Presenilin PF01080.17 CDJ48257.1 - 1.4 7.6 7.3 1.6 7.4 7.3 1.1 1 0 0 1 1 1 0 Presenilin SOBP PF15279.6 CDJ48257.1 - 1.9 9.0 8.0 2.8 8.5 8.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Apt1 PF10351.9 CDJ48257.1 - 5.6 5.7 12.5 6.3 5.5 12.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ48257.1 - 6.7 5.1 10.8 7.9 4.9 10.8 1.1 1 0 0 1 1 1 0 Macoilin family SRC-1 PF08832.10 CDJ48258.1 - 0.048 14.7 1.8 0.048 14.7 1.8 2.1 2 0 0 2 2 2 0 Steroid receptor coactivator Presenilin PF01080.17 CDJ48258.1 - 0.19 10.5 7.9 0.2 10.4 7.9 1.0 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ48258.1 - 0.96 10.4 14.3 0.11 13.4 8.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RskA PF10099.9 CDJ48258.1 - 1.3 9.3 9.8 3.2 8.0 9.8 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA YfhO PF09586.10 CDJ48258.1 - 2.1 6.5 7.7 2.1 6.5 7.7 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Comm PF15957.5 CDJ48258.1 - 4.2 7.7 7.0 1.6 9.1 4.4 1.6 2 0 0 2 2 2 0 Commissureless adh_short PF00106.25 CDJ48259.1 - 8.7e-09 35.1 0.1 1.5e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ48259.1 - 1.6e-06 27.8 0.2 1.4e-05 24.8 0.0 2.3 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ48259.1 - 0.00088 19.2 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 KR domain BHD_3 PF10405.9 CDJ48259.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 RskA PF10099.9 CDJ48260.1 - 6.1e-05 23.4 38.5 0.00027 21.3 6.1 2.3 1 1 1 2 2 2 2 Anti-sigma-K factor rskA DUF755 PF05501.11 CDJ48260.1 - 0.005 17.1 18.1 0.005 17.1 18.1 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ48260.1 - 0.0062 16.2 12.7 0.0062 16.2 12.7 3.4 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ48260.1 - 0.031 14.9 5.9 0.031 14.9 5.9 4.5 3 1 1 4 4 4 0 Immortalisation up-regulated protein DUF4692 PF15763.5 CDJ48260.1 - 0.18 12.3 25.6 0.27 11.7 4.5 3.4 3 1 0 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) Cwf_Cwc_15 PF04889.12 CDJ48260.1 - 0.95 9.1 21.7 0.37 10.5 6.9 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Lin-8 PF03353.15 CDJ48260.1 - 2.2 7.7 23.9 1.3 8.5 12.6 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Pox_A12 PF04651.13 CDJ48261.1 - 0.025 14.6 1.4 0.041 13.9 1.4 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Secretin_N_2 PF07655.13 CDJ48261.1 - 0.034 14.7 6.3 0.034 14.7 6.3 1.7 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4685 PF15737.5 CDJ48261.1 - 0.1 13.0 7.2 0.082 13.4 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) AF-4 PF05110.13 CDJ48261.1 - 0.18 9.9 7.1 0.28 9.2 7.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein BAF1_ABF1 PF04684.13 CDJ48262.1 - 0.13 11.2 14.0 0.15 11.1 14.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Macoilin PF09726.9 CDJ48262.1 - 0.57 8.7 16.7 0.73 8.3 16.7 1.2 1 0 0 1 1 1 0 Macoilin family TAF4 PF05236.14 CDJ48262.1 - 1.2 8.8 12.9 1.4 8.6 12.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Nucleo_P87 PF07267.11 CDJ48262.1 - 1.5 7.6 7.7 1.6 7.5 7.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Apt1 PF10351.9 CDJ48262.1 - 1.7 7.4 15.6 1.9 7.3 15.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ48262.1 - 2.5 7.9 20.9 2.9 7.7 20.9 1.0 1 0 0 1 1 1 0 SPX domain PknG_rubred PF16919.5 CDJ48262.1 - 2.6 8.2 8.5 4.3 7.5 8.5 1.5 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain Hamartin PF04388.12 CDJ48262.1 - 6.1 5.4 15.1 6.3 5.3 15.1 1.0 1 0 0 1 1 1 0 Hamartin protein MAP65_ASE1 PF03999.12 CDJ48262.1 - 9 4.9 11.3 9.8 4.7 11.3 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Totivirus_coat PF05518.11 CDJ48262.1 - 10 4.1 14.7 11 3.9 14.7 1.0 1 0 0 1 1 1 0 Totivirus coat protein SR-25 PF10500.9 CDJ48263.1 - 3.6e-06 26.8 24.3 3.6e-06 26.8 24.3 3.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF1645 PF07816.11 CDJ48263.1 - 0.0078 16.8 6.3 0.0078 16.8 6.3 4.2 3 2 1 4 4 3 1 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ48263.1 - 0.023 14.3 76.8 0.041 13.5 2.4 3.5 4 0 0 4 4 4 0 Spt20 family Tim54 PF11711.8 CDJ48263.1 - 0.071 11.9 23.8 0.52 9.0 5.7 3.2 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 CCD PF07860.11 CDJ48263.1 - 0.11 12.5 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 WisP family C-Terminal Region DUF2052 PF09747.9 CDJ48263.1 - 0.15 12.1 30.1 0.063 13.4 5.1 3.2 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) CCSAP PF15748.5 CDJ48263.1 - 0.28 11.3 47.0 0.64 10.1 17.5 2.6 2 1 0 2 2 2 0 Centriole, cilia and spindle-associated DUF572 PF04502.13 CDJ48263.1 - 0.33 10.5 31.9 0.28 10.7 10.7 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF572) RR_TM4-6 PF06459.12 CDJ48263.1 - 0.44 10.3 32.9 0.17 11.7 11.7 3.0 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 U1snRNP70_N PF12220.8 CDJ48263.1 - 0.79 10.4 22.8 1 10.0 4.2 3.4 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SAPS PF04499.15 CDJ48263.1 - 0.79 8.4 18.3 1.9 7.2 5.2 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Pinin_SDK_memA PF04696.13 CDJ48263.1 - 0.87 9.7 52.0 0.13 12.4 9.7 3.9 4 0 0 4 4 4 0 pinin/SDK/memA/ protein conserved region DUF4207 PF13904.6 CDJ48263.1 - 1.8 8.2 62.5 0.018 14.7 18.0 3.5 3 1 0 3 3 2 0 Domain of unknown function (DUF4207) Mit_KHE1 PF10173.9 CDJ48263.1 - 2.1 8.4 10.8 5.9 6.9 1.9 2.5 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related GREB1 PF15782.5 CDJ48263.1 - 2.7 5.0 30.8 0.33 8.0 8.3 2.2 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer MMR1 PF08505.10 CDJ48263.1 - 5.7 7.1 44.2 0.88 9.8 11.5 3.2 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein Med15 PF09606.10 CDJ48263.1 - 5.7 5.5 58.2 0.43 9.2 14.1 3.4 4 0 0 4 4 4 0 ARC105 or Med15 subunit of Mediator complex non-fungal Filament_head PF04732.14 CDJ48263.1 - 5.8 7.9 28.4 4.1 8.3 9.0 3.8 4 0 0 4 4 4 0 Intermediate filament head (DNA binding) region EPL1 PF10513.9 CDJ48263.1 - 5.9 7.3 39.3 0.067 13.6 3.3 3.5 3 1 0 3 3 3 0 Enhancer of polycomb-like Noggin PF05806.12 CDJ48263.1 - 6.2 6.7 12.0 3.5 7.5 5.1 2.6 2 0 0 2 2 2 0 Noggin FAM176 PF14851.6 CDJ48263.1 - 6.6 6.4 22.2 0.73 9.5 1.2 3.4 3 0 0 3 3 3 0 FAM176 family EF-hand_1 PF00036.32 CDJ48266.1 - 8.6e-05 21.8 0.1 0.00013 21.3 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CDJ48266.1 - 0.00011 22.6 0.0 0.00017 22.0 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ48266.1 - 0.00039 20.1 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CDJ48266.1 - 0.00051 19.4 0.1 0.0008 18.8 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CDJ48266.1 - 0.00066 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair RskA PF10099.9 CDJ48266.1 - 0.00071 19.9 16.4 0.00071 19.9 16.4 3.6 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Draxin PF15550.6 CDJ48266.1 - 2.2 8.1 36.2 1.6 8.5 27.1 2.1 2 0 0 2 2 2 0 Draxin SR-25 PF10500.9 CDJ48266.1 - 3.5 7.2 41.8 1.3 8.6 16.4 2.3 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein UPF0564 PF10595.9 CDJ48267.1 - 0.22 10.5 41.8 0.28 10.2 41.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Peptidase_S15 PF02129.18 CDJ48267.1 - 0.26 10.8 16.1 0.37 10.3 16.1 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) VIT1 PF01988.19 CDJ48267.1 - 0.99 9.2 8.4 1.6 8.5 8.4 1.4 1 0 0 1 1 1 0 VIT family TFIIA PF03153.13 CDJ48267.1 - 1.1 9.1 71.5 1.9 8.4 71.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SART-1 PF03343.13 CDJ48267.1 - 2.2 6.7 28.9 2.9 6.3 28.9 1.1 1 0 0 1 1 1 0 SART-1 family FapA PF03961.13 CDJ48267.1 - 3.8 6.0 19.0 4.7 5.7 19.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4746 PF15928.5 CDJ48267.1 - 4.5 6.6 17.2 8.6 5.7 17.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RskA PF10099.9 CDJ48268.1 - 0.00093 19.5 9.2 0.00093 19.5 9.2 15.1 5 3 7 13 13 13 2 Anti-sigma-K factor rskA SpoIIP PF07454.11 CDJ48269.1 - 0.00019 21.0 8.9 0.00021 20.9 8.9 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) PAT1 PF09770.9 CDJ48269.1 - 0.0005 18.5 20.7 0.00053 18.4 20.7 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SAPS PF04499.15 CDJ48269.1 - 0.00051 19.0 8.2 0.00054 18.9 8.2 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein V_ATPase_I PF01496.19 CDJ48269.1 - 0.00082 17.4 13.4 0.00083 17.4 13.4 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PTPRCAP PF15713.5 CDJ48269.1 - 0.00083 19.7 14.2 0.0011 19.3 14.2 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Piezo_RRas_bdg PF12166.8 CDJ48269.1 - 0.00086 18.7 4.6 0.00096 18.5 4.6 1.0 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain Pex14_N PF04695.13 CDJ48269.1 - 0.00087 20.0 19.9 0.0012 19.5 19.9 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CDJ48269.1 - 0.0011 17.9 16.0 0.0012 17.6 16.0 1.1 1 0 0 1 1 1 1 Presenilin RR_TM4-6 PF06459.12 CDJ48269.1 - 0.0027 17.6 13.1 0.0031 17.4 13.1 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CDJ48269.1 - 0.0031 17.7 10.0 0.004 17.3 10.0 1.3 1 0 0 1 1 1 1 DDHD domain DUF2151 PF10221.9 CDJ48269.1 - 0.0083 14.8 7.1 0.0088 14.7 7.1 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator DUF4045 PF13254.6 CDJ48269.1 - 0.0084 15.8 10.8 0.01 15.5 10.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) CCDC53 PF10152.9 CDJ48269.1 - 0.0096 16.3 15.1 0.013 15.9 15.1 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Velvet PF11754.8 CDJ48269.1 - 0.015 15.3 13.7 0.017 15.1 13.7 1.1 1 0 0 1 1 1 0 Velvet factor EPL1 PF10513.9 CDJ48269.1 - 0.015 15.6 13.9 0.024 15.0 13.9 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like RP-C_C PF11800.8 CDJ48269.1 - 0.016 15.3 12.8 0.022 14.9 12.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region CobT PF06213.12 CDJ48269.1 - 0.016 14.6 23.6 0.02 14.3 23.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.13 CDJ48269.1 - 0.018 13.9 14.4 0.021 13.6 14.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AF-4 PF05110.13 CDJ48269.1 - 0.02 13.0 20.2 0.022 12.9 20.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF935 PF06074.12 CDJ48269.1 - 0.033 12.9 11.7 0.041 12.6 11.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DUF913 PF06025.12 CDJ48269.1 - 0.036 13.1 8.0 0.04 12.9 8.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CSG2 PF16965.5 CDJ48269.1 - 0.038 12.9 4.2 0.038 12.9 4.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator YjbH PF06082.11 CDJ48269.1 - 0.042 12.7 7.3 0.045 12.6 7.3 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH eIF-3_zeta PF05091.12 CDJ48269.1 - 0.045 12.7 21.6 0.05 12.6 21.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ48269.1 - 0.045 13.8 11.2 0.051 13.6 11.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Exonuc_VII_L PF02601.15 CDJ48269.1 - 0.045 13.3 18.0 0.055 13.0 18.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CPSF100_C PF13299.6 CDJ48269.1 - 0.057 13.6 10.7 0.077 13.2 10.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.11 CDJ48269.1 - 0.058 12.8 5.6 0.071 12.5 5.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Afi1 PF07792.12 CDJ48269.1 - 0.062 13.8 13.3 0.077 13.5 13.3 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NARP1 PF12569.8 CDJ48269.1 - 0.065 12.1 15.3 0.084 11.8 15.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4638 PF15472.6 CDJ48269.1 - 0.069 12.9 10.8 0.081 12.6 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) TFIIA PF03153.13 CDJ48269.1 - 0.096 12.7 40.7 0.13 12.3 40.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2370 PF10176.9 CDJ48269.1 - 0.1 12.3 5.4 0.13 11.9 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) ALMT PF11744.8 CDJ48269.1 - 0.1 11.4 13.1 0.11 11.3 13.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CDC45 PF02724.14 CDJ48269.1 - 0.11 10.7 13.8 0.12 10.6 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Endostatin PF06482.11 CDJ48269.1 - 0.12 11.8 14.3 0.15 11.5 14.3 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Borrelia_P83 PF05262.11 CDJ48269.1 - 0.13 10.8 17.0 0.14 10.6 17.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Gti1_Pac2 PF09729.9 CDJ48269.1 - 0.14 12.2 15.7 0.19 11.8 15.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family GREB1 PF15782.5 CDJ48269.1 - 0.14 9.2 15.0 0.15 9.2 15.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Paf1 PF03985.13 CDJ48269.1 - 0.16 10.9 27.2 0.21 10.6 27.2 1.0 1 0 0 1 1 1 0 Paf1 Ndc1_Nup PF09531.10 CDJ48269.1 - 0.17 10.5 9.0 0.18 10.5 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TCP PF03634.13 CDJ48269.1 - 0.17 12.4 19.8 0.23 12.0 19.8 1.2 1 0 0 1 1 1 0 TCP family transcription factor Baculo_PP31 PF05311.11 CDJ48269.1 - 0.18 11.3 11.9 0.27 10.7 11.9 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) AAA_11 PF13086.6 CDJ48269.1 - 0.18 11.5 16.1 0.22 11.3 16.1 1.1 1 0 0 1 1 1 0 AAA domain Ctr PF04145.15 CDJ48269.1 - 0.22 12.1 8.7 0.31 11.6 8.7 1.4 1 0 0 1 1 1 0 Ctr copper transporter family DUF4820 PF16091.5 CDJ48269.1 - 0.23 10.8 12.9 0.33 10.3 12.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) GPCR_chapero_1 PF11904.8 CDJ48269.1 - 0.24 10.8 10.5 0.3 10.5 10.5 1.1 1 0 0 1 1 1 0 GPCR-chaperone DUF2828 PF11443.8 CDJ48269.1 - 0.25 9.4 17.4 0.3 9.1 17.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) HCO3_cotransp PF00955.21 CDJ48269.1 - 0.3 9.9 4.6 0.36 9.6 4.6 1.1 1 0 0 1 1 1 0 HCO3- transporter family SLC12 PF03522.15 CDJ48269.1 - 0.31 10.0 18.3 0.38 9.7 18.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SpoVR PF04293.13 CDJ48269.1 - 0.33 9.6 12.6 0.4 9.3 12.6 1.1 1 0 0 1 1 1 0 SpoVR like protein MCM_bind PF09739.9 CDJ48269.1 - 0.37 9.2 18.9 0.49 8.8 18.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Paramyxo_ncap PF00973.19 CDJ48269.1 - 0.38 9.6 12.1 0.48 9.3 12.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Spem1 PF15670.5 CDJ48269.1 - 0.38 10.3 20.8 0.53 9.8 20.8 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 FAM60A PF15396.6 CDJ48269.1 - 0.43 10.6 15.2 0.61 10.0 15.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 CDJ48269.1 - 0.44 8.6 16.3 0.5 8.4 16.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPP4R2 PF09184.11 CDJ48269.1 - 0.53 9.8 12.0 0.62 9.6 12.0 1.1 1 0 0 1 1 1 0 PPP4R2 DUF702 PF05142.12 CDJ48269.1 - 0.66 10.5 16.5 1.2 9.6 16.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) SelP_N PF04592.14 CDJ48269.1 - 0.67 9.3 23.7 0.86 9.0 23.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4746 PF15928.5 CDJ48269.1 - 0.7 9.3 16.6 0.91 8.9 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MAJIN PF15077.6 CDJ48269.1 - 0.82 9.4 11.6 1 9.1 11.6 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Scs3p PF10261.9 CDJ48269.1 - 0.96 8.9 3.1 1.2 8.6 3.1 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF3306 PF11748.8 CDJ48269.1 - 1 10.3 16.7 1.7 9.5 16.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Lin-8 PF03353.15 CDJ48269.1 - 1 8.9 20.9 1.3 8.5 20.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SprA-related PF12118.8 CDJ48269.1 - 1 8.4 31.5 1.2 8.2 31.5 1.2 1 0 0 1 1 1 0 SprA-related family MMR1 PF08505.10 CDJ48269.1 - 1.2 9.4 21.2 1.8 8.8 21.2 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FYDLN_acid PF09538.10 CDJ48269.1 - 1.2 9.8 10.2 2.3 9.0 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) PPL5 PF18168.1 CDJ48269.1 - 1.2 8.3 16.4 1.7 7.9 16.4 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Membralin PF09746.9 CDJ48269.1 - 1.3 7.9 13.1 1.8 7.6 13.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein PepSY_TM PF03929.16 CDJ48269.1 - 1.5 8.4 7.9 2 8.0 7.9 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Zip PF02535.22 CDJ48269.1 - 1.5 7.9 12.9 1.9 7.6 12.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter XRN_M PF17846.1 CDJ48269.1 - 1.6 7.6 12.4 1.9 7.3 12.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Peptidase_S64 PF08192.11 CDJ48269.1 - 1.6 7.1 16.8 1.9 6.8 16.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Rrn6 PF10214.9 CDJ48269.1 - 1.7 7.1 22.1 1.8 6.9 22.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4407 PF14362.6 CDJ48269.1 - 1.9 7.8 18.4 2.5 7.4 18.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Folate_carrier PF01770.18 CDJ48269.1 - 2 7.1 7.7 2.6 6.7 7.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier SID-1_RNA_chan PF13965.6 CDJ48269.1 - 2.1 6.7 9.1 2.3 6.5 9.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Band_3_cyto PF07565.13 CDJ48269.1 - 2.1 8.1 19.2 2.9 7.6 19.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Med19 PF10278.9 CDJ48269.1 - 2.1 8.3 14.3 2.8 7.8 14.3 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Ureide_permease PF07168.11 CDJ48269.1 - 2.1 7.0 8.3 2.6 6.7 8.3 1.1 1 0 0 1 1 1 0 Ureide permease CAF1 PF04857.20 CDJ48269.1 - 2.3 7.3 13.1 2.9 7.0 13.1 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease PIP5K PF01504.18 CDJ48269.1 - 2.4 7.3 16.7 3.2 6.9 16.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase OmpH PF03938.14 CDJ48269.1 - 2.5 8.5 36.3 3.6 7.9 36.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CIAPIN1 PF05093.13 CDJ48269.1 - 2.5 8.6 10.7 1.4 9.5 8.4 1.8 2 0 0 2 2 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF4050 PF13259.6 CDJ48269.1 - 2.6 8.4 16.9 3.6 7.9 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) FapA PF03961.13 CDJ48269.1 - 2.9 6.4 11.5 3.4 6.2 11.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 CDJ48269.1 - 2.9 6.7 10.1 3 6.6 10.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Rtf2 PF04641.12 CDJ48269.1 - 2.9 7.2 17.3 3.9 6.8 17.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3584 PF12128.8 CDJ48269.1 - 2.9 5.3 30.9 3.7 4.9 30.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4776 PF16003.5 CDJ48269.1 - 3 6.7 19.6 3.7 6.4 19.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Asparaginase_2 PF01112.18 CDJ48269.1 - 3.4 6.6 7.4 5.2 6.0 7.4 1.3 1 0 0 1 1 1 0 Asparaginase Connexin PF00029.19 CDJ48269.1 - 3.4 7.3 16.7 4.6 6.9 16.7 1.2 1 0 0 1 1 1 0 Connexin Peptidase_U57 PF05582.12 CDJ48269.1 - 3.6 6.8 12.5 4.7 6.4 12.5 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Serinc PF03348.15 CDJ48269.1 - 3.8 6.3 11.4 4.3 6.1 11.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFB6 PF17110.5 CDJ48269.1 - 4.5 7.0 11.1 7.2 6.3 11.1 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH AAA_23 PF13476.6 CDJ48269.1 - 6.5 7.2 22.6 7.9 6.9 22.6 1.2 1 0 0 1 1 1 0 AAA domain OATP PF03137.20 CDJ48269.1 - 6.8 4.8 9.7 9.6 4.4 9.7 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family YABBY PF04690.13 CDJ48269.1 - 7.6 7.1 18.1 11 6.5 18.1 1.2 1 0 0 1 1 1 0 YABBY protein DUF3381 PF11861.8 CDJ48269.1 - 9 6.1 26.8 15 5.3 26.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3381) Nop53 PF07767.11 CDJ48269.1 - 9.8 5.4 31.6 13 5.1 31.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SR-25 PF10500.9 CDJ48270.1 - 0.17 11.4 43.7 0.34 10.5 43.5 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein HABP4_PAI-RBP1 PF04774.15 CDJ48270.1 - 4.2 8.2 39.3 4 8.3 26.7 2.1 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Pinin_SDK_memA PF04696.13 CDJ48270.1 - 6.8 6.8 65.6 0.96 9.5 35.0 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region SR-25 PF10500.9 CDJ48271.1 - 5.4e-05 22.9 8.8 5.4e-05 22.9 8.8 6.2 5 1 1 6 6 6 3 Nuclear RNA-splicing-associated protein Helicase_C PF00271.31 CDJ48272.1 - 1.6e-09 38.0 0.0 7.7e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ48272.1 - 3.3e-07 30.3 0.0 7.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ48272.1 - 1.8e-06 28.3 0.1 1.8e-06 28.3 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 CDJ48272.1 - 6e-05 22.9 0.0 6e-05 22.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 CDJ48272.1 - 0.00023 21.5 0.0 0.00053 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CDJ48272.1 - 0.0092 15.6 0.2 0.044 13.4 0.2 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ATP-synt_E PF05680.12 CDJ48272.1 - 0.028 14.7 2.7 0.053 13.9 0.6 2.4 2 0 0 2 2 2 0 ATP synthase E chain AAA_7 PF12775.7 CDJ48272.1 - 0.033 13.7 0.0 0.033 13.7 0.0 2.3 3 0 0 3 3 2 0 P-loop containing dynein motor region T2SSE PF00437.20 CDJ48272.1 - 0.035 13.2 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 CDJ48272.1 - 0.039 13.4 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein BUD22 PF09073.10 CDJ48272.1 - 0.047 13.0 31.1 0.1 11.9 31.1 1.5 1 0 0 1 1 1 0 BUD22 ResIII PF04851.15 CDJ48272.1 - 0.055 13.5 4.6 1.5 8.8 0.0 3.1 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 CDJ48272.1 - 0.057 13.6 0.9 0.22 11.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain HemX PF04375.14 CDJ48272.1 - 0.08 12.2 10.0 0.16 11.2 10.0 1.5 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase AAA_16 PF13191.6 CDJ48272.1 - 0.097 13.0 0.0 0.097 13.0 0.0 2.5 2 1 0 2 2 1 0 AAA ATPase domain AAA_23 PF13476.6 CDJ48272.1 - 1.9 9.0 0.0 1.9 9.0 0.0 3.0 3 1 0 3 3 2 0 AAA domain DUF853 PF05872.12 CDJ48272.1 - 3 6.3 10.3 28 3.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Nucleo_P87 PF07267.11 CDJ48272.1 - 3.6 6.3 15.1 5.7 5.7 15.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Utp14 PF04615.13 CDJ48272.1 - 4.1 5.9 27.6 6.7 5.2 27.6 1.3 1 0 0 1 1 1 0 Utp14 protein FAM76 PF16046.5 CDJ48272.1 - 6 6.1 21.4 2.5 7.4 16.7 2.1 2 0 0 2 2 2 0 FAM76 protein MAP65_ASE1 PF03999.12 CDJ48272.1 - 9.1 4.8 37.7 14 4.3 37.7 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RuvB_N PF05496.12 CDJ48273.1 - 2.5e-06 27.3 0.0 3.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CDJ48273.1 - 4.3e-06 26.8 0.0 6.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CDJ48273.1 - 2.4e-05 24.8 0.0 3.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CDJ48273.1 - 6.9e-05 23.3 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CDJ48273.1 - 8.9e-05 22.4 0.2 0.00024 21.0 0.0 1.7 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDJ48273.1 - 0.00025 20.5 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CDJ48273.1 - 0.0029 17.2 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CDJ48273.1 - 0.0044 17.3 0.0 0.0069 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ48273.1 - 0.006 16.9 0.0 0.0084 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDJ48273.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.5 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CDJ48273.1 - 0.0073 15.9 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Apt1 PF10351.9 CDJ48273.1 - 0.046 12.6 2.4 0.041 12.8 2.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ48273.1 - 0.054 12.0 5.0 0.061 11.9 5.0 1.0 1 0 0 1 1 1 0 Macoilin family IstB_IS21 PF01695.17 CDJ48273.1 - 0.16 11.7 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.13 CDJ48273.1 - 0.16 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 CDJ48273.1 - 0.19 10.9 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 CDJ48273.1 - 0.19 11.4 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDJ48273.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 CDJ48273.1 - 0.2 11.7 0.0 0.38 10.7 0.0 1.5 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit TniB PF05621.11 CDJ48273.1 - 0.23 10.9 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_3 PF07726.11 CDJ48273.1 - 0.23 11.3 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CCDC106 PF15794.5 CDJ48273.1 - 0.23 11.1 2.8 0.28 10.8 2.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4614 PF15391.6 CDJ48273.1 - 1.6 8.7 9.8 2.1 8.3 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) RAP1 PF07218.11 CDJ48273.1 - 1.9 6.7 11.2 2.1 6.5 11.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Kelch_1 PF01344.25 CDJ48274.1 - 4.9e-29 99.7 0.2 5e-06 26.0 0.0 5.1 4 0 0 4 4 4 4 Kelch motif Kelch_5 PF13854.6 CDJ48274.1 - 3.5e-25 87.5 0.2 7.7e-07 29.0 0.0 4.9 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 CDJ48274.1 - 7.2e-23 80.3 1.5 4.3e-06 26.6 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ48274.1 - 1.2e-22 78.9 3.1 3.1e-05 23.8 0.0 5.7 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 CDJ48274.1 - 7.2e-19 68.1 0.0 1.7e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 CDJ48274.1 - 1.9e-18 66.0 1.0 3.3e-05 24.0 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 CDJ48274.1 - 2.8e-15 56.2 20.6 0.00013 22.2 0.0 7.8 7 1 0 7 7 7 4 Galactose oxidase, central domain SR-25 PF10500.9 CDJ48275.1 - 0.021 14.5 0.7 0.021 14.5 0.7 7.2 5 1 2 7 7 7 0 Nuclear RNA-splicing-associated protein UPF0054 PF02130.17 CDJ48276.1 - 3.3e-10 39.9 0.0 2e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein family UPF0054 ACPS PF01648.20 CDJ48276.1 - 2.8e-05 24.2 1.8 2.8e-05 24.2 1.8 3.4 2 1 2 4 4 3 1 4'-phosphopantetheinyl transferase superfamily RskA PF10099.9 CDJ48276.1 - 3.3e-05 24.3 35.8 0.00013 22.4 13.0 5.5 3 2 2 5 5 3 3 Anti-sigma-K factor rskA MMR1 PF08505.10 CDJ48276.1 - 0.00091 19.6 7.5 0.00091 19.6 7.5 3.1 2 1 0 3 3 1 1 Mitochondrial Myo2 receptor-related protein Tim54 PF11711.8 CDJ48276.1 - 0.0011 17.8 4.2 0.0032 16.3 4.2 1.7 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 RLL PF10036.9 CDJ48276.1 - 0.0062 16.4 9.8 0.0062 16.4 9.8 2.8 3 1 1 4 4 4 2 RNA transcription, translation and transport factor protein TERB2 PF15101.6 CDJ48276.1 - 0.012 15.7 13.0 0.012 15.7 13.0 2.8 3 0 0 3 3 3 0 Telomere-associated protein TERB2 TRM13 PF05206.14 CDJ48276.1 - 0.034 13.7 3.7 0.069 12.7 3.7 1.4 1 0 0 1 1 1 0 Methyltransferase TRM13 Spt20 PF12090.8 CDJ48276.1 - 0.043 13.4 47.5 0.11 12.1 37.4 2.7 3 0 0 3 3 3 0 Spt20 family Connexin PF00029.19 CDJ48276.1 - 0.079 12.7 6.5 0.17 11.6 6.5 1.5 1 0 0 1 1 1 0 Connexin DUF2207 PF09972.9 CDJ48276.1 - 0.14 10.9 0.1 0.35 9.6 0.1 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4638 PF15472.6 CDJ48276.1 - 0.23 11.2 6.9 0.45 10.2 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) RED_N PF07808.13 CDJ48276.1 - 0.33 10.5 10.5 0.77 9.3 10.5 1.6 1 0 0 1 1 1 0 RED-like protein N-terminal region eIF-3_zeta PF05091.12 CDJ48276.1 - 0.65 8.9 15.9 1 8.3 15.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4746 PF15928.5 CDJ48276.1 - 1 8.8 5.8 1.6 8.1 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) EIIBC-GUT_N PF03612.14 CDJ48276.1 - 1.2 8.9 9.6 4.1 7.1 9.6 1.9 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF1980 PF09323.10 CDJ48276.1 - 2.4 8.0 8.7 0.97 9.3 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF1115 PF06544.12 CDJ48276.1 - 3.1 7.9 8.4 7.8 6.6 8.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) PA26 PF04636.13 CDJ48276.1 - 3.9 6.3 9.8 1.2 8.0 2.8 2.3 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) DUF2681 PF10883.8 CDJ48276.1 - 4.8 7.7 28.4 18 5.8 28.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) V_ATPase_I PF01496.19 CDJ48276.1 - 5.2 4.8 12.5 9.5 4.0 12.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SpoIIP PF07454.11 CDJ48276.1 - 5.7 6.3 14.9 0.44 10.0 9.9 1.6 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) MecA PF05389.12 CDJ48276.1 - 6.2 6.4 10.8 0.55 9.8 5.7 1.8 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) CPSF100_C PF13299.6 CDJ48276.1 - 7.1 6.8 23.4 4.4 7.5 10.7 3.4 3 1 0 4 4 3 0 Cleavage and polyadenylation factor 2 C-terminal RIFIN PF02009.16 CDJ48276.1 - 7.4 6.4 30.1 0.069 13.0 8.9 3.3 3 0 0 3 3 3 0 Rifin LON_substr_bdg PF02190.16 CDJ48277.1 - 0.014 15.3 0.0 0.053 13.4 0.0 1.9 2 0 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain SUIM_assoc PF16619.5 CDJ48277.1 - 3.7 7.7 13.3 0.69 10.0 6.8 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Tau95_N PF17682.1 CDJ48278.1 - 0.67 10.1 7.2 0.77 10.0 7.2 1.1 1 0 0 1 1 1 0 Tau95 Triple barrel domain SRP-alpha_N PF04086.13 CDJ48279.1 - 0.071 13.0 13.2 0.077 12.9 13.2 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CRF1 PF10380.9 CDJ48279.1 - 0.11 12.9 3.7 0.11 12.8 3.7 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Pex14_N PF04695.13 CDJ48279.1 - 0.34 11.5 17.4 0.35 11.5 17.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5321 PF17254.2 CDJ48279.1 - 0.36 10.3 13.3 0.42 10.0 13.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5321) TORC_N PF12884.7 CDJ48279.1 - 0.6 10.9 18.3 0.71 10.7 18.3 1.1 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus Spt20 PF12090.8 CDJ48279.1 - 0.82 9.2 33.6 0.91 9.1 33.6 1.1 1 0 0 1 1 1 0 Spt20 family CobT PF06213.12 CDJ48279.1 - 0.85 9.0 16.8 0.98 8.7 16.8 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4834 PF16118.5 CDJ48279.1 - 1.1 10.2 13.0 1.4 9.9 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CNDH2_N PF06278.11 CDJ48279.1 - 1.1 9.5 9.4 1.4 9.2 9.4 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Folliculin PF11704.8 CDJ48279.1 - 1.9 8.4 9.7 2 8.3 9.7 1.0 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Suf PF05843.14 CDJ48279.1 - 2.7 7.9 16.6 2.6 7.9 16.6 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.17 CDJ48279.1 - 3.9 7.6 11.4 4 7.5 11.4 1.0 1 0 0 1 1 1 0 DDHD domain DUF3464 PF11947.8 CDJ48279.1 - 4.1 7.1 12.8 4.2 7.1 12.8 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Coilin_N PF15862.5 CDJ48279.1 - 5 6.9 15.9 5.5 6.8 15.9 1.1 1 0 0 1 1 1 0 Coilin N-terminus SpoIIP PF07454.11 CDJ48279.1 - 5.1 6.5 13.1 5.1 6.5 13.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EIIBC-GUT_N PF03612.14 CDJ48279.1 - 5.2 6.8 10.8 5.2 6.8 10.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TFIIA PF03153.13 CDJ48279.1 - 5.3 6.9 31.6 5.5 6.9 31.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1980 PF09323.10 CDJ48279.1 - 5.5 6.9 9.5 5.7 6.8 9.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 CDJ48279.1 - 5.8 5.6 14.3 5.8 5.6 14.3 1.0 1 0 0 1 1 1 0 Presenilin PEX11 PF05648.14 CDJ48279.1 - 6.7 6.1 8.3 6.9 6.1 8.3 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) AIF_C PF14721.6 CDJ48279.1 - 8.3 6.8 9.6 9.5 6.6 9.6 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RR_TM4-6 PF06459.12 CDJ48279.1 - 9.2 6.0 13.4 9.6 5.9 13.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RskA PF10099.9 CDJ48281.1 - 0.02 15.2 0.3 0.02 15.2 0.3 11.1 3 3 4 8 8 8 0 Anti-sigma-K factor rskA Adeno_PX PF05829.12 CDJ48284.1 - 0.12 12.2 0.2 0.12 12.2 0.2 2.9 3 0 0 3 3 3 0 Adenovirus late L2 mu core protein (Protein X) SPX PF03105.19 CDJ48285.1 - 0.00085 19.3 1.5 0.00085 19.3 1.5 1.1 1 0 0 1 1 1 1 SPX domain Thr_synth_N PF14821.6 CDJ48285.1 - 0.0016 18.6 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 Threonine synthase N terminus DUF4614 PF15391.6 CDJ48285.1 - 0.048 13.7 16.1 0.074 13.0 16.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF4820 PF16091.5 CDJ48285.1 - 0.097 12.0 1.5 0.14 11.5 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Sec3_C PF09763.9 CDJ48285.1 - 0.31 9.4 3.0 0.37 9.1 3.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 HSD3 PF15244.6 CDJ48285.1 - 1 8.8 10.7 1.3 8.4 10.7 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 CCDC85 PF10226.9 CDJ48285.1 - 1.2 8.7 6.5 2.2 7.9 6.5 1.4 1 0 0 1 1 1 0 CCDC85 family Apt1 PF10351.9 CDJ48285.1 - 2.9 6.7 14.6 3.8 6.2 14.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Miga PF10265.9 CDJ48285.1 - 3 6.7 9.6 3.8 6.4 9.6 1.1 1 0 0 1 1 1 0 Mitoguardin DUF515 PF04415.12 CDJ48285.1 - 3.3 6.0 24.8 4.3 5.6 24.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF3458_C PF17432.2 CDJ48286.1 - 8.2e-88 294.8 9.1 1.2e-87 294.3 9.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats DUF3458 PF11940.8 CDJ48286.1 - 1e-07 32.3 0.4 3.3e-07 30.7 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1 PF01433.20 CDJ48286.1 - 1.9e-07 30.9 0.0 2.2e-06 27.4 0.0 2.4 1 1 0 1 1 1 1 Peptidase family M1 domain BDV_P10 PF06515.11 CDJ48288.1 - 6.2 6.9 7.8 5.8 7.0 0.7 2.3 2 0 0 2 2 2 0 Borna disease virus P10 protein TFIIA PF03153.13 CDJ48289.1 - 1.9 8.4 22.2 2.3 8.1 22.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ48289.1 - 2.3 8.1 11.7 2.4 8.1 11.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RskA PF10099.9 CDJ48290.1 - 2.4 8.4 9.0 1.8 8.9 6.2 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DNA_pol_B_palm PF14792.6 CDJ48292.1 - 1.2e-08 35.1 0.1 1.2e-08 35.1 0.1 4.7 5 0 0 5 5 5 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 CDJ48292.1 - 0.00016 21.4 0.2 0.00016 21.4 0.2 3.1 4 0 0 4 4 4 1 Fingers domain of DNA polymerase lambda SPX PF03105.19 CDJ48292.1 - 0.00099 19.1 8.6 0.00099 19.1 8.6 4.8 3 2 0 3 3 3 1 SPX domain DUF2722 PF10846.8 CDJ48292.1 - 0.002 17.2 10.5 0.002 17.2 10.5 5.7 2 1 2 4 4 4 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ48292.1 - 0.0025 17.5 16.7 0.0025 17.5 16.7 5.8 3 1 2 5 5 5 1 Spt20 family SseC PF04888.12 CDJ48292.1 - 0.0032 17.1 33.0 0.0032 17.1 33.0 9.1 5 4 2 7 7 7 1 Secretion system effector C (SseC) like family NTP_transf_2 PF01909.23 CDJ48292.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain SID-1_RNA_chan PF13965.6 CDJ48292.1 - 2.6 6.4 11.1 6.9 5.0 5.6 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 LMBR1 PF04791.16 CDJ48292.1 - 8.1 5.2 16.4 8.8 5.1 0.7 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein Adaptin_binding PF10199.9 CDJ48292.1 - 9.3 6.9 41.2 0.14 12.8 19.4 4.6 3 2 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 DUF4179 PF13786.6 CDJ48293.1 - 0.0079 16.6 1.7 0.011 16.1 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) Activator_LAG-3 PF11498.8 CDJ48293.1 - 0.011 14.8 17.4 0.012 14.6 17.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med3 PF11593.8 CDJ48293.1 - 0.32 10.1 19.1 0.38 9.9 19.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CDPS PF16715.5 CDJ48293.1 - 0.39 10.3 6.6 0.48 10.0 6.6 1.0 1 0 0 1 1 1 0 Cyclodipeptide synthase SMYLE_N PF18615.1 CDJ48293.1 - 0.72 9.4 7.4 0.92 9.0 7.4 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Chorion_2 PF03964.15 CDJ48293.1 - 0.78 10.6 12.7 1.3 9.9 12.7 1.4 1 0 0 1 1 1 0 Chorion family 2 DUF2232 PF09991.9 CDJ48293.1 - 1 8.4 3.2 1.2 8.2 3.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) EIF4E-T PF10477.9 CDJ48293.1 - 1.4 7.7 9.9 1.5 7.5 9.9 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF3533 PF12051.8 CDJ48293.1 - 1.5 7.7 6.4 1.7 7.5 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF3123 PF11321.8 CDJ48293.1 - 2.6 8.7 6.0 3.7 8.2 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3123) TFIIA PF03153.13 CDJ48293.1 - 2.8 7.9 20.8 3.2 7.6 20.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAE2 PF08573.10 CDJ48293.1 - 3 9.0 7.0 5 8.3 7.0 1.4 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DOR PF14839.6 CDJ48293.1 - 5.6 6.8 13.8 6.8 6.6 13.8 1.1 1 0 0 1 1 1 0 DOR family Med6 PF04934.14 CDJ48294.1 - 6.2e-06 26.0 0.6 6.2e-06 26.0 0.6 2.5 2 1 0 2 2 1 1 MED6 mediator sub complex component DUF755 PF05501.11 CDJ48294.1 - 0.0041 17.4 25.2 0.0041 17.4 25.2 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF755) PilP PF04351.13 CDJ48294.1 - 0.0091 16.0 1.7 0.0091 16.0 1.7 2.4 2 0 0 2 2 2 1 Pilus assembly protein, PilP AF-4 PF05110.13 CDJ48294.1 - 0.023 12.8 23.8 0.0087 14.2 15.9 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Pkinase_fungal PF17667.1 CDJ48294.1 - 0.048 12.4 11.1 0.024 13.4 7.5 1.9 2 0 0 2 2 2 0 Fungal protein kinase DUF4667 PF15700.5 CDJ48294.1 - 0.1 12.7 19.7 0.26 11.4 13.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Plasmodium_Vir PF05795.11 CDJ48294.1 - 0.24 10.8 10.4 0.21 11.0 3.9 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF3506 PF12014.8 CDJ48294.1 - 0.44 10.6 7.3 0.43 10.6 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) Apt1 PF10351.9 CDJ48294.1 - 0.44 9.4 16.0 0.17 10.7 11.0 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain MACPF PF01823.19 CDJ48294.1 - 0.48 10.5 8.3 2.6 8.1 6.4 2.2 2 0 0 2 2 2 0 MAC/Perforin domain MPM1 PF17234.2 CDJ48294.1 - 0.97 9.7 23.9 0.081 13.2 7.9 2.9 3 0 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 Rrn6 PF10214.9 CDJ48294.1 - 1.6 7.2 22.8 0.076 11.5 11.0 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Ndc1_Nup PF09531.10 CDJ48294.1 - 1.9 7.1 22.2 5.8 5.5 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Herpes_pp85 PF04637.12 CDJ48294.1 - 1.9 6.8 6.0 2.7 6.3 6.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3824 PF12868.7 CDJ48294.1 - 3.2 8.4 15.3 7.9 7.1 6.0 2.7 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF1645 PF07816.11 CDJ48294.1 - 3.3 8.2 25.4 0.056 14.0 12.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) Peptidase_S64 PF08192.11 CDJ48294.1 - 4.6 5.6 23.8 1.4 7.4 17.1 2.0 2 0 0 2 2 2 0 Peptidase family S64 DUF3446 PF11928.8 CDJ48294.1 - 6.4 7.2 20.8 0.13 12.6 12.9 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain RAP1 PF07218.11 CDJ48294.1 - 7.1 4.8 6.7 9.9 4.3 6.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Neur_chan_memb PF02932.16 CDJ48294.1 - 8.1 6.4 18.9 9.5 6.2 11.6 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.18 CDJ48294.1 - 8.8 4.6 7.7 0.94 7.8 3.5 1.5 2 0 0 2 2 2 0 Membrane transport protein SR-25 PF10500.9 CDJ48294.1 - 9.3 5.8 34.9 34 3.9 31.2 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ48295.1 - 0.0034 16.2 5.1 0.0034 16.2 5.1 2.5 2 1 0 2 2 2 1 Presenilin FAM60A PF15396.6 CDJ48295.1 - 0.019 15.0 1.0 0.019 15.0 1.0 2.4 3 0 0 3 3 3 0 Protein Family FAM60A SpoIIP PF07454.11 CDJ48295.1 - 0.51 9.8 14.5 0.044 13.2 2.2 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Suf PF05843.14 CDJ48295.1 - 3.1 7.7 21.8 0.013 15.5 7.3 2.9 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Zip PF02535.22 CDJ48295.1 - 4.9 6.3 12.7 0.044 13.0 3.9 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Baculo_PP31 PF05311.11 CDJ48295.1 - 7.3 6.0 16.7 0.8 9.1 7.9 2.3 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) EOS1 PF12326.8 CDJ48295.1 - 7.6 6.4 7.4 4.3 7.2 2.7 2.3 2 0 0 2 2 2 0 N-glycosylation protein Sporozoite_P67 PF05642.11 CDJ48296.1 - 0.23 9.5 24.4 0.16 10.0 18.6 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Apt1 PF10351.9 CDJ48296.1 - 0.91 8.3 29.6 0.81 8.5 1.5 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain CCSAP PF15748.5 CDJ48296.1 - 0.97 9.5 58.7 2.2 8.4 40.1 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Lin-8 PF03353.15 CDJ48296.1 - 1 8.9 54.3 2.2 7.8 36.6 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF4045 PF13254.6 CDJ48296.1 - 1.9 8.0 48.4 0.38 10.3 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) ETRAMP PF09716.10 CDJ48296.1 - 4.6 7.4 0.0 4.6 7.4 0.0 3.3 3 1 1 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) SOBP PF15279.6 CDJ48296.1 - 5.1 7.6 41.7 3.6 8.1 8.1 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Kinesin PF00225.23 CDJ48297.1 - 2.2e-14 53.1 0.0 3.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF2722 PF10846.8 CDJ48298.1 - 0.00039 19.5 0.5 0.00039 19.5 0.5 27.2 21 7 1 24 24 24 5 Protein of unknown function (DUF2722) EIF4E-T PF10477.9 CDJ48298.1 - 4.9 5.8 0.0 4.9 5.8 0.0 15.1 11 7 2 13 13 13 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E SARAF PF06682.12 CDJ48300.1 - 0.0023 17.7 7.8 0.0023 17.7 7.8 2.2 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 CDJ48300.1 - 0.0028 18.6 17.5 0.0028 18.6 17.5 3.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4834) DUF908 PF06012.12 CDJ48300.1 - 2 7.8 32.9 2.4 7.5 32.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Oxidored_q3 PF00499.20 CDJ48300.1 - 2.8 7.7 5.8 8.7 6.1 5.8 2.1 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Wzy_C PF04932.15 CDJ48300.1 - 10 5.8 5.8 0.71 9.5 0.7 1.8 2 1 0 2 2 2 0 O-Antigen ligase RskA PF10099.9 CDJ48301.1 - 5.8e-07 30.0 13.3 6.7e-07 29.8 13.3 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF755 PF05501.11 CDJ48301.1 - 0.00028 21.1 18.6 0.00028 21.1 18.6 3.1 2 1 1 3 3 2 1 Domain of unknown function (DUF755) rRNA_processing PF08524.11 CDJ48301.1 - 0.0013 18.8 11.5 0.0022 18.1 11.5 1.4 1 0 0 1 1 1 1 rRNA processing Trp_oprn_chp PF09534.10 CDJ48301.1 - 0.0026 17.6 2.8 0.0032 17.3 2.8 1.2 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SprA-related PF12118.8 CDJ48301.1 - 0.012 14.8 31.6 0.014 14.6 31.6 1.2 1 0 0 1 1 1 0 SprA-related family HemX PF04375.14 CDJ48301.1 - 0.013 14.9 13.3 0.013 14.9 13.3 1.5 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase FHIPEP PF00771.20 CDJ48301.1 - 0.12 10.9 4.2 0.15 10.5 4.2 1.1 1 0 0 1 1 1 0 FHIPEP family BAF1_ABF1 PF04684.13 CDJ48301.1 - 0.14 11.2 19.1 0.15 11.1 19.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.14 CDJ48301.1 - 0.17 11.8 20.1 0.2 11.6 20.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CD20 PF04103.15 CDJ48301.1 - 0.24 11.5 4.8 0.56 10.3 0.0 2.2 2 0 0 2 2 2 0 CD20-like family eIF-3_zeta PF05091.12 CDJ48301.1 - 0.29 10.1 17.8 0.35 9.8 17.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Mito_fiss_reg PF05308.11 CDJ48301.1 - 0.34 10.9 17.4 0.57 10.2 17.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator VIT1 PF01988.19 CDJ48301.1 - 0.35 10.7 3.1 0.61 9.9 3.1 1.3 1 0 0 1 1 1 0 VIT family Spt20 PF12090.8 CDJ48301.1 - 0.55 9.8 39.2 0.043 13.4 21.8 2.1 2 0 0 2 2 2 0 Spt20 family PepSY_2 PF13670.6 CDJ48301.1 - 0.79 9.8 7.4 1.2 9.2 7.4 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain MACPF PF01823.19 CDJ48301.1 - 1 9.4 20.5 0.88 9.6 6.3 2.1 2 0 0 2 2 2 0 MAC/Perforin domain DUF4407 PF14362.6 CDJ48301.1 - 1.2 8.4 11.3 1.4 8.2 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HA2 PF04408.23 CDJ48301.1 - 1.5 9.2 9.8 0.1 12.9 4.3 1.8 2 0 0 2 2 2 0 Helicase associated domain (HA2) Abhydrolase_9_N PF15420.6 CDJ48301.1 - 9.5 6.2 8.7 0.54 10.2 3.3 1.6 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Macoilin PF09726.9 CDJ48302.1 - 0.00049 18.8 84.6 0.002 16.8 37.5 2.9 3 0 0 3 3 3 2 Macoilin family Herpes_LMP1 PF05297.11 CDJ48302.1 - 5.7 6.0 5.4 15 4.7 5.4 1.7 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SUIM_assoc PF16619.5 CDJ48303.1 - 0.98 9.5 0.0 0.98 9.5 0.0 7.9 3 3 3 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 SID-1_RNA_chan PF13965.6 CDJ48303.1 - 8.3 4.7 14.2 2.3 6.5 10.6 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Lip_prot_lig_C PF10437.9 CDJ48304.1 - 1.1e-14 54.1 0.0 2.1e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus RskA PF10099.9 CDJ48304.1 - 6.2 7.1 26.4 3.1 8.1 12.6 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Syja_N PF02383.18 CDJ48306.1 - 3.3e-10 39.8 11.3 1.5e-09 37.6 11.3 2.0 1 1 0 1 1 1 1 SacI homology domain DUF4667 PF15700.5 CDJ48306.1 - 0.00026 21.2 9.8 0.0031 17.7 5.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ48306.1 - 0.0023 17.6 29.5 0.01 15.5 4.3 2.2 2 0 0 2 2 2 2 Spt20 family GHMP_kinases_N PF00288.26 CDJ48306.1 - 0.0091 16.2 2.2 0.0091 16.2 2.2 2.2 2 1 0 2 2 1 1 GHMP kinases N terminal domain Ribosomal_60s PF00428.19 CDJ48306.1 - 0.035 14.7 5.1 0.035 14.7 5.1 1.9 2 0 0 2 2 1 0 60s Acidic ribosomal protein DivIC PF04977.15 CDJ48306.1 - 0.25 11.2 25.9 0.44 10.4 12.0 2.3 2 0 0 2 2 2 0 Septum formation initiator RAB3GAP2_N PF14655.6 CDJ48306.1 - 0.32 10.2 11.4 0.9 8.7 0.3 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AF-4 PF05110.13 CDJ48306.1 - 0.71 7.9 23.2 0.079 11.0 9.3 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Gaa1 PF04114.14 CDJ48306.1 - 0.79 8.7 2.5 3.1 6.7 0.1 2.1 2 1 0 2 2 2 0 Gaa1-like, GPI transamidase component Rsc14 PF08586.10 CDJ48306.1 - 2.3 9.1 7.7 5 8.0 0.1 2.4 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit eIF-3_zeta PF05091.12 CDJ48306.1 - 2.7 6.9 10.5 0.81 8.6 3.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1645 PF07816.11 CDJ48306.1 - 4.7 7.8 21.6 0.093 13.3 7.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) OmpH PF03938.14 CDJ48306.1 - 5 7.5 30.3 3.1 8.1 7.6 2.9 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) YABBY PF04690.13 CDJ48306.1 - 5.3 7.6 7.6 16 6.0 0.4 2.3 2 0 0 2 2 2 0 YABBY protein DUF2489 PF10675.9 CDJ48306.1 - 7.2 6.5 24.5 2.6 8.0 10.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Syja_N PF02383.18 CDJ48307.1 - 6.4e-11 42.1 2.3 6.4e-11 42.1 2.3 1.6 2 0 0 2 2 2 1 SacI homology domain Spore_III_AF PF09581.10 CDJ48307.1 - 0.0039 17.2 2.8 0.016 15.2 2.8 2.0 1 1 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) Ribosomal_60s PF00428.19 CDJ48307.1 - 0.17 12.5 0.2 0.17 12.5 0.2 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ48307.1 - 1.6 8.3 35.8 0.61 9.6 18.5 2.3 2 0 0 2 2 2 0 Spt20 family Caudo_TAP PF02413.17 CDJ48307.1 - 4.8 7.3 16.7 13 5.9 10.2 2.4 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK MAT1 PF06391.13 CDJ48307.1 - 5.7 6.7 12.3 16 5.2 0.2 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Histone_HNS PF00816.21 CDJ48307.1 - 6.2 7.7 20.7 0.35 11.7 7.1 3.2 3 0 0 3 3 3 0 H-NS histone family TERB2 PF15101.6 CDJ48307.1 - 6.3 6.8 10.9 24 4.9 7.0 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF2722 PF10846.8 CDJ48307.1 - 7 5.5 28.2 0.055 12.4 10.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RAB3GAP2_N PF14655.6 CDJ48307.1 - 7.5 5.7 11.9 8.8 5.5 0.2 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4834 PF16118.5 CDJ48307.1 - 9.4 7.3 13.0 16 6.5 6.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SID-1_RNA_chan PF13965.6 CDJ48308.1 - 0.023 13.1 1.6 0.03 12.8 1.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 CDJ48308.1 - 0.056 11.7 19.7 0.063 11.5 19.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.10 CDJ48308.1 - 0.14 10.8 37.3 0.19 10.4 37.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Connexin PF00029.19 CDJ48308.1 - 0.81 9.4 6.7 1.3 8.8 6.7 1.3 1 0 0 1 1 1 0 Connexin CSG2 PF16965.5 CDJ48308.1 - 1.1 8.1 2.2 1.5 7.7 2.2 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator RR_TM4-6 PF06459.12 CDJ48308.1 - 1.6 8.5 12.3 2.6 7.8 12.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 CDJ48308.1 - 2 7.8 8.9 3 7.2 8.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) V_ATPase_I PF01496.19 CDJ48308.1 - 2.1 6.2 10.6 2.8 5.7 10.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1980 PF09323.10 CDJ48308.1 - 2.1 8.2 4.3 3 7.7 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Macoilin PF09726.9 CDJ48308.1 - 2.4 6.6 16.8 3.4 6.1 16.8 1.3 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 CDJ48308.1 - 2.5 7.6 23.1 3.7 7.0 23.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PA26 PF04636.13 CDJ48308.1 - 3.4 6.5 13.3 4.7 6.0 13.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 CDJ48308.1 - 4.6 5.9 18.9 7.8 5.2 18.9 1.4 1 0 0 1 1 1 0 Presenilin Nucleo_P87 PF07267.11 CDJ48308.1 - 4.7 5.9 16.9 6.6 5.5 16.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 eIF-3_zeta PF05091.12 CDJ48308.1 - 5.2 5.9 18.9 8.8 5.2 18.9 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GREB1 PF15782.5 CDJ48308.1 - 7.7 3.5 24.0 8.9 3.3 24.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 CDJ48308.1 - 8.4 5.1 10.7 14 4.4 10.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter SUIM_assoc PF16619.5 CDJ48309.1 - 0.016 15.2 0.7 0.016 15.2 0.7 4.3 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 UPF0542 PF15086.6 CDJ48309.1 - 2 8.4 4.2 12 5.9 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 EphA2_TM PF14575.6 CDJ48309.1 - 4.1 8.4 4.3 79 4.2 1.3 2.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RAP1 PF07218.11 CDJ48310.1 - 0.041 12.2 11.0 0.051 11.9 11.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Inositol_P PF00459.25 CDJ48311.1 - 1.6e-14 54.1 0.3 0.0005 19.7 0.0 4.4 4 0 0 4 4 4 3 Inositol monophosphatase family DUF4834 PF16118.5 CDJ48312.1 - 0.016 16.2 9.9 0.13 13.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Coilin_N PF15862.5 CDJ48312.1 - 0.018 14.8 10.8 0.083 12.7 0.0 2.1 2 0 0 2 2 2 0 Coilin N-terminus TFIIA PF03153.13 CDJ48312.1 - 0.1 12.5 21.2 0.13 12.2 21.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIP5K PF01504.18 CDJ48312.1 - 0.16 11.2 3.6 0.2 10.8 3.6 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF4551 PF15087.6 CDJ48312.1 - 0.96 8.2 11.4 1.2 7.9 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) V_ATPase_I PF01496.19 CDJ48312.1 - 1.1 7.1 8.9 1.3 6.8 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ48312.1 - 1.3 7.7 13.8 1.7 7.4 13.8 1.1 1 0 0 1 1 1 0 Presenilin SARAF PF06682.12 CDJ48312.1 - 1.4 8.5 12.5 1.8 8.2 12.5 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis NPR3 PF03666.13 CDJ48312.1 - 1.7 7.4 9.9 1.1 7.9 2.9 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 CDJ48312.1 - 1.9 7.4 8.1 2.6 7.0 8.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF3474 PF11960.8 CDJ48312.1 - 2 8.6 4.2 0.87 9.8 1.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3474) DUF2828 PF11443.8 CDJ48312.1 - 2.1 6.4 8.3 2.6 6.0 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Hid1 PF12722.7 CDJ48312.1 - 3.6 5.6 10.2 4.6 5.3 10.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF908 PF06012.12 CDJ48312.1 - 4.8 6.5 11.5 6.5 6.1 11.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Neur_chan_memb PF02932.16 CDJ48312.1 - 4.9 7.1 8.2 7.8 6.5 8.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2615 PF11027.8 CDJ48312.1 - 6.4 7.0 12.4 0.24 11.5 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Lin-8 PF03353.15 CDJ48312.1 - 9.4 5.7 14.4 12 5.4 14.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ALMT PF11744.8 CDJ48312.1 - 9.6 4.9 7.0 13 4.5 7.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CBFD_NFYB_HMF PF00808.23 CDJ48313.1 - 0.34 11.2 10.0 0.1 12.9 2.1 2.7 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2207 PF09972.9 CDJ48314.1 - 0.00068 18.5 1.0 0.00078 18.3 1.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF3522 PF12036.8 CDJ48314.1 - 0.001 19.4 0.2 0.0013 19.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) SPX PF03105.19 CDJ48314.1 - 0.0014 18.6 12.2 0.0017 18.3 12.2 1.1 1 0 0 1 1 1 1 SPX domain DUF2615 PF11027.8 CDJ48314.1 - 0.0022 18.1 1.3 0.024 14.8 0.9 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2615) EphA2_TM PF14575.6 CDJ48314.1 - 0.0028 18.5 0.9 0.0028 18.5 0.9 2.5 1 1 2 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain Apt1 PF10351.9 CDJ48314.1 - 0.0032 16.4 11.9 0.0043 16.0 11.9 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain SID-1_RNA_chan PF13965.6 CDJ48314.1 - 0.0092 14.4 3.4 0.012 14.0 3.4 1.3 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Amnionless PF14828.6 CDJ48314.1 - 0.027 13.3 2.1 0.032 13.1 2.1 1.1 1 0 0 1 1 1 0 Amnionless DUF4834 PF16118.5 CDJ48314.1 - 0.034 15.1 6.1 0.034 15.1 6.1 2.8 1 1 2 3 3 2 0 Domain of unknown function (DUF4834) DUF3784 PF12650.7 CDJ48314.1 - 0.039 14.1 7.3 0.057 13.6 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) SecG PF03840.14 CDJ48314.1 - 0.078 13.1 14.8 0.054 13.6 7.9 2.4 2 0 0 2 2 2 0 Preprotein translocase SecG subunit TMEM208_SND2 PF05620.11 CDJ48314.1 - 0.087 12.6 2.5 0.13 12.0 2.5 1.4 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF572 PF04502.13 CDJ48314.1 - 0.11 12.1 2.4 0.15 11.6 2.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SdpI PF13630.6 CDJ48314.1 - 0.11 12.6 7.5 0.16 12.1 7.5 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family Peptidase_M56 PF05569.11 CDJ48314.1 - 0.25 10.5 5.3 0.31 10.2 5.3 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 NICE-3 PF07406.11 CDJ48314.1 - 0.37 10.8 1.9 0.59 10.1 1.9 1.3 1 0 0 1 1 1 0 NICE-3 protein SNARE PF05739.19 CDJ48314.1 - 0.39 10.8 16.8 5.7 7.0 0.1 2.7 2 0 0 2 2 2 0 SNARE domain Pex24p PF06398.11 CDJ48314.1 - 0.41 9.6 6.0 0.3 10.0 4.8 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF2371 PF10177.9 CDJ48314.1 - 0.45 10.7 4.9 0.63 10.2 4.2 1.5 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) Ac81 PF05820.11 CDJ48314.1 - 0.77 9.3 5.2 1.1 8.9 5.2 1.1 1 0 0 1 1 1 0 Baculoviridae AC81 TMEM154 PF15102.6 CDJ48314.1 - 1.1 9.2 24.8 4.5 7.2 24.8 2.0 1 1 0 1 1 1 0 TMEM154 protein family EBP50_C PF09007.11 CDJ48314.1 - 2.2 9.3 22.8 0.2 12.7 7.2 2.1 2 0 0 2 2 2 0 EBP50, C-terminal Uds1 PF15456.6 CDJ48314.1 - 2.2 8.4 10.5 9.4 6.4 6.6 2.2 2 0 0 2 2 2 0 Up-regulated During Septation MSC PF09402.10 CDJ48314.1 - 2.2 7.6 4.9 2.8 7.3 4.9 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Stevor PF17410.2 CDJ48314.1 - 3 7.3 14.3 1.5 8.3 12.6 1.3 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3404 PF11884.8 CDJ48314.1 - 3.8 6.7 7.1 9.5 5.3 7.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3404) DUF3328 PF11807.8 CDJ48314.1 - 4.8 6.9 8.8 1.4 8.6 5.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) DUF1645 PF07816.11 CDJ48314.1 - 5.8 7.4 25.7 4.9 7.7 7.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Shisa PF13908.6 CDJ48314.1 - 7.2 6.8 18.9 9.8 6.4 17.7 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF5385 PF17359.2 CDJ48314.1 - 7.3 6.1 15.2 0.047 13.2 5.9 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5385) Plasmodium_Vir PF05795.11 CDJ48314.1 - 7.6 5.8 11.8 14 5.0 11.8 1.4 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Ribosomal_60s PF00428.19 CDJ48314.1 - 9.4 6.9 11.8 8.2 7.1 3.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein LZ_Tnp_IS66 PF13007.7 CDJ48315.1 - 0.19 12.5 0.0 0.19 12.5 0.0 3.1 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain DUF4366 PF14283.6 CDJ48315.1 - 0.79 9.8 7.0 0.16 12.0 2.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) MAPEG PF01124.18 CDJ48315.1 - 1.7 8.6 5.9 3.1 7.7 5.9 1.6 1 1 0 1 1 1 0 MAPEG family Peptidase_M30 PF10460.9 CDJ48315.1 - 2.8 6.8 5.6 4.3 6.2 5.6 1.2 1 0 0 1 1 1 0 Peptidase M30 VIR_N PF15912.5 CDJ48316.1 - 1 8.9 26.2 1.3 8.6 24.0 1.9 2 0 0 2 2 2 0 Virilizer, N-terminal Paf1 PF03985.13 CDJ48316.1 - 7 5.5 39.6 1.2 8.1 32.4 2.3 2 0 0 2 2 2 0 Paf1 PDGF PF00341.17 CDJ48317.1 - 0.15 12.4 0.6 0.3 11.4 0.6 1.5 1 0 0 1 1 1 0 PDGF/VEGF domain RskA PF10099.9 CDJ48317.1 - 1.1 9.6 10.6 0.13 12.6 4.5 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA AIRS_C PF02769.22 CDJ48318.1 - 1.8e-15 57.4 4.6 2.8e-13 50.3 3.4 3.3 4 0 0 4 4 4 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 CDJ48318.1 - 6.6e-09 36.3 8.7 6.6e-09 36.3 8.7 3.9 3 2 0 4 4 4 1 AIR synthase related protein, N-terminal domain Shadoo PF14999.6 CDJ48318.1 - 0.0086 16.2 19.4 0.0086 16.2 19.4 5.1 4 1 1 5 5 5 2 Shadow of prion protein, neuroprotective Spt20 PF12090.8 CDJ48318.1 - 0.11 12.1 25.9 0.022 14.4 4.9 2.3 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ48318.1 - 0.12 11.3 16.3 0.02 13.8 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ48318.1 - 5 7.0 7.8 12 5.8 1.3 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 CDJ48318.1 - 7.5 7.6 10.4 18 6.4 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PAP2_3 PF14378.6 CDJ48319.1 - 0.05 13.3 0.0 0.084 12.5 0.0 1.6 1 1 0 1 1 1 0 PAP2 superfamily Cellulose_synt PF03552.14 CDJ48319.1 - 1.9 6.9 4.7 2.5 6.5 4.7 1.2 1 0 0 1 1 1 0 Cellulose synthase Presenilin PF01080.17 CDJ48319.1 - 4.8 5.8 19.1 1.4 7.6 13.4 2.0 2 0 0 2 2 2 0 Presenilin O-antigen_lig PF13425.6 CDJ48319.1 - 7 5.3 8.2 0.84 8.4 4.4 1.4 1 1 0 1 1 1 0 O-antigen ligase like membrane protein DHHC PF01529.20 CDJ48321.1 - 2.8e-08 33.9 4.7 2.8e-08 33.9 4.7 2.4 3 0 0 3 3 3 1 DHHC palmitoyltransferase BUD22 PF09073.10 CDJ48321.1 - 0.0067 15.8 2.6 0.0067 15.8 2.6 4.3 2 2 1 4 4 4 1 BUD22 SID-1_RNA_chan PF13965.6 CDJ48324.1 - 0.28 9.5 5.9 0.39 9.1 5.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spore_coat_CotO PF14153.6 CDJ48324.1 - 0.46 10.4 32.2 0.43 10.5 22.7 2.3 2 0 0 2 2 2 0 Spore coat protein CotO SAPS PF04499.15 CDJ48324.1 - 0.71 8.6 14.7 1.1 8.0 14.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF-3_zeta PF05091.12 CDJ48324.1 - 0.89 8.5 27.7 0.59 9.0 17.6 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Activator_LAG-3 PF11498.8 CDJ48324.1 - 3.3 6.6 59.0 2.9 6.8 36.1 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Connexin PF00029.19 CDJ48324.1 - 9.6 5.9 18.3 21 4.8 13.3 2.1 2 0 0 2 2 2 0 Connexin DUF1645 PF07816.11 CDJ48326.1 - 0.041 14.5 14.0 0.035 14.7 9.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) NPAT_C PF15712.5 CDJ48326.1 - 0.77 8.3 23.6 0.069 11.8 0.6 2.0 2 0 0 2 2 2 0 NPAT C terminus PAT1 PF09770.9 CDJ48326.1 - 2 6.6 35.1 2.8 6.1 35.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ48326.1 - 2.1 7.9 25.5 1.8 8.1 20.8 2.2 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF5349 PF17298.2 CDJ48326.1 - 2.9 7.6 33.9 0.16 11.7 2.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5349) NST1 PF13945.6 CDJ48326.1 - 3.7 7.6 26.9 2.6 8.1 16.1 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator IHABP4_N PF16174.5 CDJ48326.1 - 8.6 6.9 23.7 18 5.9 18.0 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Exonuc_VII_L PF02601.15 CDJ48327.1 - 9.9e-06 25.3 6.8 1.4e-05 24.9 6.8 1.5 1 0 0 1 1 1 1 Exonuclease VII, large subunit Rrn6 PF10214.9 CDJ48327.1 - 0.0013 17.4 19.6 0.0016 17.1 19.6 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Miga PF10265.9 CDJ48327.1 - 0.0019 17.3 17.8 0.0026 16.8 17.8 1.2 1 0 0 1 1 1 1 Mitoguardin ALMT PF11744.8 CDJ48327.1 - 0.074 11.9 8.9 0.083 11.7 8.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 CDJ48327.1 - 0.32 9.7 20.9 0.44 9.2 20.9 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ48327.1 - 0.36 10.8 50.8 0.011 15.8 44.1 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MAT1 PF06391.13 CDJ48327.1 - 0.7 9.7 26.0 1.1 9.1 26.0 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 eIF-3_zeta PF05091.12 CDJ48327.1 - 1.1 8.2 19.8 1.7 7.6 19.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PA26 PF04636.13 CDJ48327.1 - 1.1 8.1 16.3 1.4 7.7 16.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PAT1 PF09770.9 CDJ48327.1 - 2.1 6.5 37.8 2.7 6.1 37.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ48327.1 - 2.1 7.5 7.3 3.9 6.6 7.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CDJ48327.1 - 2.5 8.1 16.7 4.7 7.2 16.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 CDJ48327.1 - 4.3 6.2 21.5 5.8 5.8 21.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 V_ATPase_I PF01496.19 CDJ48327.1 - 7.3 4.4 18.3 9.2 4.0 18.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gti1_Pac2 PF09729.9 CDJ48327.1 - 9.3 6.3 14.1 4.4 7.4 12.1 1.6 2 0 0 2 2 2 0 Gti1/Pac2 family Rhodanese PF00581.20 CDJ48328.1 - 2.9e-10 40.6 0.0 0.0026 18.3 0.0 4.0 2 2 0 2 2 2 2 Rhodanese-like domain Peroxin-3 PF04882.12 CDJ48328.1 - 0.0054 15.8 9.2 0.0054 15.8 9.2 2.4 3 0 0 3 3 3 1 Peroxin-3 Plasmodium_Vir PF05795.11 CDJ48328.1 - 0.0087 15.5 0.3 0.015 14.7 0.3 1.3 1 0 0 1 1 1 1 Plasmodium vivax Vir protein CCDC53 PF10152.9 CDJ48328.1 - 0.017 15.6 8.3 0.017 15.6 8.3 3.6 3 2 0 3 3 1 0 Subunit CCDC53 of WASH complex Kei1 PF08552.11 CDJ48328.1 - 0.041 13.8 0.4 0.041 13.8 0.4 3.5 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2235 PF09994.9 CDJ48328.1 - 0.049 13.0 0.9 0.096 12.0 0.9 1.4 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) SLC12 PF03522.15 CDJ48328.1 - 0.084 11.9 5.0 0.15 11.1 5.0 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Otopetrin PF03189.13 CDJ48328.1 - 0.12 11.2 0.1 1.8 7.3 0.1 2.1 2 0 0 2 2 2 0 Otopetrin SPX PF03105.19 CDJ48328.1 - 0.17 11.7 15.6 0.02 14.8 10.9 1.9 2 1 0 2 2 1 0 SPX domain Presenilin PF01080.17 CDJ48328.1 - 0.38 9.5 16.2 0.01 14.6 8.6 2.0 3 0 0 3 3 3 0 Presenilin Hid1 PF12722.7 CDJ48328.1 - 0.47 8.5 4.7 0.86 7.7 4.7 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Connexin PF00029.19 CDJ48328.1 - 0.95 9.2 7.2 2.1 8.1 7.2 1.5 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 CDJ48328.1 - 0.97 8.3 3.0 1.6 7.6 3.0 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Folate_carrier PF01770.18 CDJ48328.1 - 1.3 7.6 3.2 2.3 6.9 3.2 1.3 1 0 0 1 1 1 0 Reduced folate carrier DUF2828 PF11443.8 CDJ48328.1 - 3.7 5.5 9.3 6.9 4.6 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) LMBR1 PF04791.16 CDJ48328.1 - 4.4 6.1 5.2 6.3 5.6 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CNDH2_M PF16869.5 CDJ48328.1 - 4.9 7.9 13.6 0.17 12.6 0.7 3.4 4 0 0 4 4 4 0 PF16858 CSG2 PF16965.5 CDJ48328.1 - 5.1 5.9 4.2 9.4 5.1 4.2 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator EFTUD2 PF16004.5 CDJ48328.1 - 5.4 7.6 14.2 3.2 8.4 10.3 2.4 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EPL1 PF10513.9 CDJ48328.1 - 5.7 7.3 13.2 0.15 12.5 3.4 2.8 4 0 0 4 4 3 0 Enhancer of polycomb-like CLN3 PF02487.17 CDJ48328.1 - 6.5 5.7 8.2 13 4.6 8.2 1.4 1 0 0 1 1 1 0 CLN3 protein TFIIA PF03153.13 CDJ48329.1 - 7.2e-08 32.8 59.9 3.1e-05 24.2 30.5 3.4 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 CDJ48329.1 - 0.00023 19.6 13.8 0.0016 16.8 6.2 2.1 2 0 0 2 2 2 2 CDC45-like protein DDHD PF02862.17 CDJ48329.1 - 0.002 18.3 15.8 0.068 13.3 6.5 3.0 3 0 0 3 3 3 2 DDHD domain NPR3 PF03666.13 CDJ48329.1 - 0.002 17.0 9.2 0.002 17.0 9.2 2.3 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 SAGA-Tad1 PF12767.7 CDJ48329.1 - 0.0065 16.2 20.3 0.032 14.0 10.6 2.7 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit Lin-8 PF03353.15 CDJ48329.1 - 0.0071 16.0 14.7 0.0071 16.0 14.7 2.3 2 0 0 2 2 2 1 Ras-mediated vulval-induction antagonist Pex14_N PF04695.13 CDJ48329.1 - 0.018 15.7 7.9 0.018 15.7 7.9 5.0 4 1 0 4 4 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SNase PF00565.17 CDJ48329.1 - 0.037 14.5 0.0 0.57 10.7 0.0 5.1 5 1 1 6 6 3 0 Staphylococcal nuclease homologue SLC12 PF03522.15 CDJ48329.1 - 0.042 12.9 23.6 0.38 9.7 16.5 2.3 2 0 0 2 2 2 0 Solute carrier family 12 DUF3043 PF11241.8 CDJ48329.1 - 0.061 13.4 0.1 0.061 13.4 0.1 5.2 5 1 1 6 6 3 0 Protein of unknown function (DUF3043) LTV PF04180.14 CDJ48329.1 - 0.085 12.6 19.4 0.031 14.0 7.4 2.3 2 0 0 2 2 2 0 Low temperature viability protein AAA_11 PF13086.6 CDJ48329.1 - 0.16 11.8 23.1 3.9 7.2 16.6 2.9 3 0 0 3 3 3 0 AAA domain DUF2207 PF09972.9 CDJ48329.1 - 0.16 10.7 3.0 0.64 8.7 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) O-antigen_lig PF13425.6 CDJ48329.1 - 0.17 10.6 9.7 0.21 10.3 6.8 2.0 2 0 0 2 2 2 0 O-antigen ligase like membrane protein DUF2052 PF09747.9 CDJ48329.1 - 0.19 11.9 29.3 0.62 10.2 17.9 2.7 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Orf78 PF06024.12 CDJ48329.1 - 0.32 11.3 0.0 0.32 11.3 0.0 3.7 2 1 1 3 3 1 0 Orf78 (ac78) ABC2_membrane_2 PF12679.7 CDJ48329.1 - 0.38 10.0 12.6 4.3 6.5 6.9 2.9 2 1 0 2 2 2 0 ABC-2 family transporter protein Pkinase_fungal PF17667.1 CDJ48329.1 - 0.44 9.3 12.5 1.3 7.8 8.2 2.2 2 0 0 2 2 2 0 Fungal protein kinase CSG2 PF16965.5 CDJ48329.1 - 0.5 9.3 7.8 7.4 5.4 4.9 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator Afi1 PF07792.12 CDJ48329.1 - 0.61 10.6 27.4 0.087 13.3 11.3 3.2 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking HCO3_cotransp PF00955.21 CDJ48329.1 - 0.63 8.8 6.7 1.3 7.7 4.3 2.0 2 0 0 2 2 2 0 HCO3- transporter family MCM_bind PF09739.9 CDJ48329.1 - 0.63 8.4 28.7 0.0053 15.3 13.6 2.1 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor Velvet PF11754.8 CDJ48329.1 - 0.69 9.8 29.0 0.91 9.4 12.7 3.0 3 0 0 3 3 3 0 Velvet factor CLN3 PF02487.17 CDJ48329.1 - 0.9 8.5 19.7 1.4 7.9 11.8 2.3 2 0 0 2 2 2 0 CLN3 protein Presenilin PF01080.17 CDJ48329.1 - 1.1 7.9 40.1 0.15 10.8 2.0 2.6 3 0 0 3 3 3 0 Presenilin BAF1_ABF1 PF04684.13 CDJ48329.1 - 1.2 8.1 32.0 0.022 13.8 9.8 3.3 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor SAPS PF04499.15 CDJ48329.1 - 1.2 7.8 16.0 0.95 8.2 8.6 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SRP-alpha_N PF04086.13 CDJ48329.1 - 1.3 8.9 33.5 0.39 10.6 0.5 3.6 4 0 0 4 4 3 0 Signal recognition particle, alpha subunit, N-terminal PIP5K PF01504.18 CDJ48329.1 - 1.5 8.0 17.9 4.7 6.4 0.9 2.4 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase ALMT PF11744.8 CDJ48329.1 - 2.2 7.0 19.5 1.5 7.5 11.7 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter UPF0565 PF10561.9 CDJ48329.1 - 3.2 6.9 12.6 11 5.1 5.2 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0565 GREB1 PF15782.5 CDJ48329.1 - 3.4 4.6 23.8 1 6.4 14.2 2.1 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer MMR1 PF08505.10 CDJ48329.1 - 7.8 6.7 40.8 1.3 9.2 17.1 3.0 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein SURF2 PF05477.11 CDJ48332.1 - 2.3 7.9 13.8 2.3 7.8 13.8 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SR-25 PF10500.9 CDJ48332.1 - 3.6 7.1 24.7 3.9 7.0 24.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4746 PF15928.5 CDJ48332.1 - 6.5 6.1 13.6 7.4 5.9 13.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Spt20 PF12090.8 CDJ48332.1 - 9.5 5.8 20.6 11 5.5 20.6 1.1 1 0 0 1 1 1 0 Spt20 family Spt20 PF12090.8 CDJ48333.1 - 0.2 11.3 15.5 0.22 11.1 15.5 1.1 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ48333.1 - 8.4 5.1 14.9 9 5.0 14.9 1.2 1 0 0 1 1 1 0 Androgen receptor Na_H_Exchanger PF00999.21 CDJ48336.1 - 2e-09 36.7 4.4 2e-09 36.7 4.4 2.3 1 1 0 2 2 2 1 Sodium/hydrogen exchanger family SR-25 PF10500.9 CDJ48336.1 - 0.6 9.7 17.0 1.1 8.9 17.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ48338.1 - 0.00018 20.6 8.8 0.00018 20.6 8.8 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) MID_MedPIWI PF18296.1 CDJ48338.1 - 0.0038 17.1 5.3 0.0038 17.1 5.3 2.1 2 0 0 2 2 2 1 MID domain of medPIWI Peroxin-13_N PF04088.13 CDJ48338.1 - 0.0046 17.2 2.2 0.0046 17.2 2.2 2.6 2 1 1 3 3 3 1 Peroxin 13, N-terminal region CAF1 PF04857.20 CDJ48338.1 - 0.012 14.9 1.3 0.016 14.4 1.3 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF4834 PF16118.5 CDJ48338.1 - 0.016 16.2 17.1 0.13 13.3 5.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Eapp_C PF10238.9 CDJ48338.1 - 0.02 15.0 0.1 0.02 15.0 0.1 2.7 3 0 0 3 3 3 0 E2F-associated phosphoprotein Presenilin PF01080.17 CDJ48338.1 - 0.025 13.4 10.7 0.0081 15.0 5.7 2.0 2 0 0 2 2 2 0 Presenilin DUF2828 PF11443.8 CDJ48338.1 - 0.026 12.6 4.6 0.036 12.2 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3391 PF11871.8 CDJ48338.1 - 0.037 14.5 0.3 0.037 14.5 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) SpoIIP PF07454.11 CDJ48338.1 - 0.043 13.3 6.8 0.064 12.7 2.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RAMP4 PF06624.12 CDJ48338.1 - 0.048 13.7 0.5 0.048 13.7 0.5 2.2 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DUF4079 PF13301.6 CDJ48338.1 - 0.048 13.8 1.5 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF2126 PF09899.9 CDJ48338.1 - 0.066 11.3 1.6 0.083 10.9 1.6 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) ABC2_membrane_2 PF12679.7 CDJ48338.1 - 0.077 12.3 2.6 0.12 11.6 0.0 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein Orf78 PF06024.12 CDJ48338.1 - 0.084 13.2 0.7 0.084 13.2 0.7 2.6 3 0 0 3 3 3 0 Orf78 (ac78) Peptidase_S49_N PF08496.10 CDJ48338.1 - 0.11 12.6 8.7 0.062 13.4 3.1 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF2227 PF09988.9 CDJ48338.1 - 0.19 11.6 2.0 1.9 8.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) WBP-1 PF11669.8 CDJ48338.1 - 0.2 12.3 0.3 0.2 12.3 0.3 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 XRN_M PF17846.1 CDJ48338.1 - 0.25 10.3 2.2 0.36 9.7 2.2 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF2207 PF09972.9 CDJ48338.1 - 0.42 9.3 0.6 0.66 8.7 0.1 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) SSP160 PF06933.11 CDJ48338.1 - 0.61 8.2 7.5 0.79 7.9 7.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4366 PF14283.6 CDJ48338.1 - 0.67 10.0 4.6 0.77 9.8 2.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) CrgA PF06781.12 CDJ48338.1 - 0.89 9.7 4.1 0.55 10.3 0.6 2.3 2 0 0 2 2 2 0 Cell division protein CrgA DUF4667 PF15700.5 CDJ48338.1 - 1.3 9.0 21.0 0.76 9.8 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) EIIBC-GUT_N PF03612.14 CDJ48338.1 - 1.7 8.4 10.1 0.82 9.4 4.0 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Rxt3 PF08642.10 CDJ48338.1 - 2 9.2 8.0 0.58 10.9 0.3 2.7 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 RAP1 PF07218.11 CDJ48338.1 - 2.2 6.5 5.7 3.1 6.0 5.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Jak1_Phl PF17887.1 CDJ48338.1 - 4.8 7.2 12.7 1.3 9.0 6.3 2.3 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain DUF4175 PF13779.6 CDJ48338.1 - 5.3 4.8 35.1 10 3.9 35.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RskA PF10099.9 CDJ48338.1 - 5.8 7.2 34.5 14 5.9 17.8 2.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA PigN PF04987.14 CDJ48338.1 - 6.9 5.4 5.1 1.2 7.9 0.4 1.8 2 0 0 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) AUX_IAA PF02309.16 CDJ48338.1 - 7.7 6.3 12.3 80 3.0 12.3 2.0 1 1 0 1 1 1 0 AUX/IAA family DUF3408 PF11888.8 CDJ48338.1 - 9.9 6.3 15.6 10 6.3 9.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) LRR_9 PF14580.6 CDJ48339.1 - 2e-36 125.1 0.6 2.1e-36 125.1 0.6 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CDJ48339.1 - 9.9e-10 38.5 6.7 1.9e-05 24.9 0.6 2.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ48339.1 - 2.3e-08 33.7 2.0 1.2e-07 31.3 0.3 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 CDJ48339.1 - 0.0037 17.6 4.5 9.8 7.2 0.2 4.2 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 CDJ48339.1 - 0.049 13.7 3.7 35 4.8 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich repeat SR-25 PF10500.9 CDJ48341.1 - 0.034 13.8 14.4 0.058 13.0 14.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ48341.1 - 0.15 12.0 31.9 0.21 11.6 31.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S30 PF01577.16 CDJ48341.1 - 0.44 10.1 5.6 0.66 9.5 5.6 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease Use1 PF09753.9 CDJ48341.1 - 0.69 9.6 10.5 0.97 9.1 10.5 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 AAA_23 PF13476.6 CDJ48341.1 - 1 9.8 9.1 1.3 9.5 9.1 1.1 1 0 0 1 1 1 0 AAA domain DUF4757 PF15949.5 CDJ48341.1 - 1.5 9.2 14.9 2.1 8.8 14.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) GREB1 PF15782.5 CDJ48341.1 - 1.8 5.6 11.5 1.8 5.6 11.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SMYLE_N PF18615.1 CDJ48341.1 - 3.2 7.2 13.1 4.5 6.7 13.1 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PAT1 PF09770.9 CDJ48341.1 - 5.5 5.1 16.7 5.8 5.1 16.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Troponin PF00992.20 CDJ48341.1 - 6.1 7.1 11.7 9.8 6.5 11.7 1.2 1 0 0 1 1 1 0 Troponin DUF2722 PF10846.8 CDJ48342.1 - 9.2e-05 21.6 8.1 9.2e-05 21.6 8.1 2.2 2 0 0 2 2 1 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ48342.1 - 0.00015 22.2 7.8 0.00015 22.2 7.8 2.9 1 1 0 2 2 2 1 Anti-sigma-K factor rskA Pex14_N PF04695.13 CDJ48342.1 - 0.011 16.3 4.5 0.011 16.3 4.5 3.4 2 1 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region POX PF07526.11 CDJ48342.1 - 0.016 15.8 5.2 0.016 15.8 5.2 3.2 3 1 0 3 3 3 0 Associated with HOX Orf78 PF06024.12 CDJ48342.1 - 0.017 15.4 3.8 0.24 11.7 0.1 3.0 3 0 0 3 3 3 0 Orf78 (ac78) Secretin_N_2 PF07655.13 CDJ48342.1 - 0.02 15.4 7.7 0.02 15.4 7.7 3.4 3 1 0 3 3 3 0 Secretin N-terminal domain DUF3464 PF11947.8 CDJ48342.1 - 0.02 14.6 0.7 0.02 14.6 0.7 2.5 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 MecA PF05389.12 CDJ48342.1 - 0.027 14.1 6.5 0.09 12.4 1.9 2.2 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Eapp_C PF10238.9 CDJ48342.1 - 0.11 12.6 5.7 0.065 13.3 0.9 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Connexin PF00029.19 CDJ48342.1 - 0.15 11.8 4.9 0.073 12.8 0.5 2.3 2 1 1 3 3 3 0 Connexin FAM176 PF14851.6 CDJ48342.1 - 0.19 11.4 3.0 0.55 9.9 0.7 2.3 2 0 0 2 2 2 0 FAM176 family GET2 PF08690.10 CDJ48342.1 - 0.74 9.4 16.4 0.2 11.3 2.0 2.5 2 0 0 2 2 2 0 GET complex subunit GET2 Med15 PF09606.10 CDJ48342.1 - 0.91 8.1 33.3 0.1 11.3 15.6 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF726 PF05277.12 CDJ48342.1 - 1.1 8.1 9.0 0.68 8.8 7.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF726) EIIBC-GUT_N PF03612.14 CDJ48342.1 - 1.2 8.8 12.0 0.095 12.4 5.8 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus SpoIIP PF07454.11 CDJ48342.1 - 3.7 6.9 9.5 0.22 11.0 3.4 1.8 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF3391 PF11871.8 CDJ48342.1 - 3.9 8.0 16.6 0.74 10.3 2.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) SID-1_RNA_chan PF13965.6 CDJ48342.1 - 4.2 5.7 6.9 8.2 4.7 6.1 1.7 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 CDJ48342.1 - 6.6 6.5 10.5 0.53 10.1 4.3 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Activator_LAG-3 PF11498.8 CDJ48343.1 - 9.9 5.0 16.3 20 4.0 16.3 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pex14_N PF04695.13 CDJ48345.1 - 0.0054 17.4 23.3 0.0066 17.1 23.3 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4366 PF14283.6 CDJ48345.1 - 0.025 14.6 8.2 0.031 14.3 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) BAF1_ABF1 PF04684.13 CDJ48345.1 - 0.23 10.5 18.6 0.26 10.3 18.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF913 PF06025.12 CDJ48345.1 - 0.24 10.3 11.5 0.25 10.3 11.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2076 PF09849.9 CDJ48345.1 - 0.44 10.6 31.3 0.63 10.0 31.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Band_3_cyto PF07565.13 CDJ48345.1 - 0.44 10.3 17.3 0.47 10.2 17.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain EOS1 PF12326.8 CDJ48345.1 - 0.62 10.0 7.8 0.78 9.7 7.8 1.2 1 0 0 1 1 1 0 N-glycosylation protein PTPRCAP PF15713.5 CDJ48345.1 - 1.2 9.4 21.3 1.5 9.1 21.3 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FAM76 PF16046.5 CDJ48345.1 - 1.6 8.0 22.5 1.7 7.9 22.5 1.0 1 0 0 1 1 1 0 FAM76 protein Connexin PF00029.19 CDJ48345.1 - 1.9 8.2 15.2 2 8.1 15.2 1.1 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 CDJ48345.1 - 2.5 6.3 19.3 2.6 6.2 19.3 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 CDJ48345.1 - 3.1 7.4 12.6 3.9 7.1 12.6 1.2 1 0 0 1 1 1 0 FAM176 family GRA6 PF05084.13 CDJ48345.1 - 4 7.4 9.8 4.7 7.1 9.8 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DDRGK PF09756.9 CDJ48345.1 - 5 6.7 28.3 5.6 6.5 28.3 1.0 1 0 0 1 1 1 0 DDRGK domain DUF2514 PF10721.9 CDJ48345.1 - 5 7.1 28.9 6.6 6.7 28.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Gti1_Pac2 PF09729.9 CDJ48345.1 - 5.2 7.1 18.5 6.2 6.9 18.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2052 PF09747.9 CDJ48345.1 - 5.4 7.1 21.0 6.3 6.9 21.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Tim54 PF11711.8 CDJ48345.1 - 5.4 5.7 18.4 6.2 5.5 18.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4045 PF13254.6 CDJ48345.1 - 5.7 6.5 20.4 6.5 6.3 20.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RR_TM4-6 PF06459.12 CDJ48345.1 - 7.1 6.4 23.7 8.2 6.2 23.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ48345.1 - 8.1 5.1 26.3 9.1 4.9 26.3 1.0 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ48345.1 - 8.1 6.3 44.2 10 6.0 44.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ48345.1 - 8.7 5.2 20.7 10 5.0 20.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ48345.1 - 8.8 5.8 23.6 10 5.6 23.6 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PARG_cat PF05028.14 CDJ48346.1 - 3.7e-80 269.8 0.0 5.4e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) SNARE_assoc PF09335.11 CDJ48347.1 - 7.5e-16 58.7 9.6 9.2e-15 55.2 6.9 2.4 2 0 0 2 2 2 2 SNARE associated Golgi protein DUF3087 PF11286.8 CDJ48347.1 - 1.3 8.4 3.0 0.65 9.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) zf-RING_2 PF13639.6 CDJ48348.1 - 3.6e-09 36.8 12.4 7.2e-09 35.8 12.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CDJ48348.1 - 2.2e-06 27.9 9.4 4.8e-06 26.8 9.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CDJ48348.1 - 5.9e-06 25.9 1.0 1.2e-05 25.0 1.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDJ48348.1 - 5e-05 23.1 11.5 5e-05 23.1 11.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ48348.1 - 0.00064 19.5 7.1 0.0013 18.6 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ48348.1 - 0.0013 18.7 3.4 0.0029 17.6 3.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ48348.1 - 0.0054 16.6 8.9 0.011 15.5 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ48348.1 - 0.0057 16.6 10.2 0.012 15.6 10.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CDJ48348.1 - 0.062 13.4 4.6 0.11 12.5 4.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CDJ48348.1 - 0.076 12.6 10.2 0.16 11.6 10.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 CDJ48348.1 - 0.3 11.2 8.4 0.57 10.4 8.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Med3 PF11593.8 CDJ48348.1 - 0.56 9.3 19.4 0.027 13.7 13.2 1.9 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal zf-RING_4 PF14570.6 CDJ48348.1 - 1.8 8.5 5.5 3.8 7.4 5.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain REC114-like PF15165.6 CDJ48348.1 - 2.6 7.8 6.4 6.8 6.4 6.4 1.6 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like TFIIA PF03153.13 CDJ48348.1 - 3.2 7.7 22.2 0.21 11.6 16.8 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Apc15p PF05841.11 CDJ48348.1 - 4.2 8.2 15.9 1.8 9.4 3.1 2.9 2 0 0 2 2 2 0 Apc15p protein DUF4658 PF15555.6 CDJ48349.1 - 0.091 12.9 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) DUF2975 PF11188.8 CDJ48349.1 - 0.18 11.7 0.8 0.41 10.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) FixS PF03597.15 CDJ48349.1 - 0.18 11.5 3.0 0.12 12.1 0.8 1.8 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type LapA_dom PF06305.11 CDJ48349.1 - 0.31 10.9 2.2 0.38 10.6 0.2 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2367 PF10164.9 CDJ48349.1 - 6.3 7.4 8.0 10 6.7 1.4 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) TFIIE-A_C PF11521.8 CDJ48350.1 - 0.43 10.9 7.3 0.22 11.9 1.5 2.9 2 1 1 3 3 3 0 C-terminal general transcription factor TFIIE alpha BAF1_ABF1 PF04684.13 CDJ48352.1 - 3.1 6.8 25.3 3.7 6.5 25.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Radial_spoke_3 PF06098.11 CDJ48354.1 - 2.6e-09 36.8 16.2 2.6e-09 36.8 16.2 2.2 3 1 0 3 3 3 1 Radial spoke protein 3 zf-U11-48K PF05253.12 CDJ48355.1 - 0.00017 21.4 0.0 0.00042 20.1 0.0 1.8 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger TRM13 PF05206.14 CDJ48355.1 - 0.013 15.1 0.6 0.13 11.7 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase TRM13 DUF775 PF05603.12 CDJ48355.1 - 0.18 11.4 0.5 0.3 10.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Spt20 PF12090.8 CDJ48355.1 - 0.41 10.2 7.2 0.71 9.4 7.2 1.3 1 0 0 1 1 1 0 Spt20 family Vac14_Fig4_bd PF11916.8 CDJ48356.1 - 1.5e-35 122.4 0.0 1e-34 119.8 0.0 2.2 1 1 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CDJ48356.1 - 1.5e-30 105.6 0.0 3.1e-28 98.2 0.0 2.8 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CDJ48356.1 - 7.7e-11 41.3 0.2 0.019 15.2 0.0 5.3 4 0 0 4 4 4 3 HEAT repeat Tti2 PF10521.9 CDJ48356.1 - 0.00056 19.5 4.3 0.41 10.1 0.0 3.9 3 1 0 3 3 3 2 Tti2 family Cnd1 PF12717.7 CDJ48356.1 - 0.00067 19.7 0.0 4.9 7.2 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ48356.1 - 0.00081 19.7 4.6 0.48 10.8 0.0 5.2 2 1 2 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 CDJ48356.1 - 0.2 12.2 15.3 0.67 10.5 0.0 5.9 6 0 0 6 6 6 0 HEAT-like repeat PPR_2 PF13041.6 CDJ48357.1 - 1.2e-10 41.4 0.2 6.1e-05 23.1 0.0 4.4 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.20 CDJ48357.1 - 1.2e-09 37.7 4.9 0.043 14.1 0.0 6.2 7 0 0 7 7 7 2 PPR repeat PPR_long PF17177.4 CDJ48357.1 - 1.2e-08 34.6 0.0 1.2e-08 34.6 0.0 4.0 4 1 1 5 5 5 1 Pentacotripeptide-repeat region of PRORP DcuA_DcuB PF03605.14 CDJ48357.1 - 0.066 12.1 3.1 0.12 11.2 2.5 1.7 1 1 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter PPR_3 PF13812.6 CDJ48357.1 - 0.11 12.6 0.0 11 6.2 0.0 3.5 3 1 1 4 4 4 0 Pentatricopeptide repeat domain TPR_3 PF07720.12 CDJ48357.1 - 0.17 12.0 2.4 1.2 9.3 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TrbC PF04956.13 CDJ48357.1 - 0.37 11.0 4.5 10 6.4 2.3 3.5 4 0 0 4 4 4 0 TrbC/VIRB2 family SF3A2 PF16835.5 CDJ48358.1 - 2e-26 92.1 0.0 3.5e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CDJ48358.1 - 2.3e-07 31.0 1.4 4.4e-07 30.1 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Glyoxalase PF00903.25 CDJ48359.1 - 1.2e-09 38.4 0.0 9.3e-08 32.3 0.0 2.9 3 1 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CDJ48359.1 - 0.012 15.9 0.0 0.28 11.5 0.0 2.3 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RVP_2 PF08284.11 CDJ48360.1 - 6.5e-10 38.9 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ48360.1 - 1.6e-08 35.1 0.0 3.8e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ48360.1 - 2.7e-08 34.3 0.0 5.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 CDJ48360.1 - 3.6e-06 26.7 0.0 1e-05 25.2 0.0 1.7 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 CDJ48360.1 - 0.00099 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ48360.1 - 0.011 16.0 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.26 CDJ48361.1 - 3.3e-10 40.2 0.0 5.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Acetyltransf_1 PF00583.25 CDJ48363.1 - 1.2e-10 41.6 0.0 2.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ48363.1 - 2.2e-08 34.4 0.0 4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ48363.1 - 1.2e-05 25.2 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Herpes_pp85 PF04637.12 CDJ48363.1 - 0.044 12.2 1.7 0.062 11.7 1.7 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) REC114-like PF15165.6 CDJ48363.1 - 0.048 13.5 1.1 0.079 12.7 1.1 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Presenilin PF01080.17 CDJ48363.1 - 0.054 12.2 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 Presenilin 7tm_6 PF02949.20 CDJ48363.1 - 0.057 12.5 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 7tm Odorant receptor LMBR1 PF04791.16 CDJ48364.1 - 5.7e-10 38.7 0.0 1.7e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF1980 PF09323.10 CDJ48364.1 - 0.1 12.5 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF1180 PF06679.12 CDJ48364.1 - 0.4 11.1 8.8 0.13 12.7 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF2569 PF10754.9 CDJ48364.1 - 1.7 9.1 13.6 0.21 12.0 0.6 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2569) Sec20 PF03908.13 CDJ48365.1 - 0.04 13.8 3.1 0.073 13.0 1.8 2.1 2 0 0 2 2 2 0 Sec20 PHM7_cyt PF14703.6 CDJ48365.1 - 1.1 9.5 5.5 1.2 9.4 0.7 3.0 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Asp_protease_2 PF13650.6 CDJ48366.1 - 1.2e-06 29.1 0.0 2.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ48366.1 - 2.6e-06 27.9 0.0 7.3e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ48366.1 - 2.1e-05 24.3 0.0 4.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 CDJ48367.1 - 4.5e-19 68.9 0.1 8.6e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ48367.1 - 4.8e-17 61.8 0.0 8.4e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ48367.1 - 2e-08 34.4 0.1 4.5e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ48368.1 - 0.041 14.2 0.0 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ48369.1 - 2.5e-07 30.9 0.0 3.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain ABC_tran PF00005.27 CDJ48370.1 - 2.4e-23 83.1 0.1 3.6e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CDJ48370.1 - 1.3e-20 73.7 11.7 7e-20 71.3 11.9 2.1 3 0 0 3 3 3 1 ABC-2 type transporter AAA_16 PF13191.6 CDJ48370.1 - 0.00013 22.3 0.1 0.00029 21.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CDJ48370.1 - 0.00015 21.7 0.2 0.12 12.2 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDJ48370.1 - 0.00022 21.2 0.4 0.00039 20.4 0.4 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 CDJ48370.1 - 0.00064 19.4 0.1 0.0012 18.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.7 CDJ48370.1 - 0.0014 17.8 13.1 0.0042 16.2 12.6 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 CDJ48370.1 - 0.003 17.3 0.4 0.0075 16.0 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CDJ48370.1 - 0.0045 17.5 0.1 0.011 16.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 CDJ48370.1 - 0.0086 16.2 0.7 0.016 15.3 0.7 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 CDJ48370.1 - 0.023 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ48370.1 - 0.026 13.8 0.1 0.045 13.0 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 CDJ48370.1 - 0.036 14.2 0.5 0.066 13.3 0.5 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_28 PF13521.6 CDJ48370.1 - 0.044 14.0 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4158 PF13700.6 CDJ48370.1 - 0.11 12.4 0.0 9.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) DEAD PF00270.29 CDJ48372.1 - 5.3e-34 117.5 0.0 3.1e-24 85.7 0.0 2.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ48372.1 - 1.7e-23 83.0 0.0 3.1e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ48372.1 - 0.0024 17.9 0.0 0.0046 17.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ48372.1 - 0.0083 16.4 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Peptidase_M41 PF01434.18 CDJ48373.1 - 1.3e-45 155.6 0.5 1.7e-44 152.0 0.0 2.5 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 CDJ48373.1 - 9.9e-19 68.1 0.1 2.6e-18 66.7 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ48373.1 - 2e-08 33.9 0.3 5e-08 32.6 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain Presenilin PF01080.17 CDJ48373.1 - 0.094 11.5 22.8 0.066 12.0 0.2 3.2 3 0 0 3 3 3 0 Presenilin DUF2870 PF11069.8 CDJ48373.1 - 4.2 7.8 14.2 0.72 10.3 5.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Peptidase_S8 PF00082.22 CDJ48374.1 - 1.7e-44 152.3 6.3 1.7e-44 152.3 6.3 1.9 2 0 0 2 2 2 1 Subtilase family Macoilin PF09726.9 CDJ48375.1 - 0.00015 20.5 0.2 0.00015 20.5 0.2 4.4 2 2 1 5 5 5 2 Macoilin family SR-25 PF10500.9 CDJ48375.1 - 0.0007 19.3 5.0 0.0007 19.3 5.0 5.2 4 2 1 5 5 5 1 Nuclear RNA-splicing-associated protein UPF0051 PF01458.17 CDJ48376.1 - 3.2e-43 148.0 0.0 4.8e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF2722 PF10846.8 CDJ48376.1 - 5.9e-05 22.2 15.7 0.012 14.6 6.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) PH_5 PF15405.6 CDJ48376.1 - 0.0033 17.5 0.7 0.0033 17.5 0.7 2.8 2 1 1 3 3 3 1 Pleckstrin homology domain SR-25 PF10500.9 CDJ48376.1 - 0.0035 17.0 12.7 0.0035 17.0 12.7 2.2 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein PBD PF00786.28 CDJ48376.1 - 0.23 11.8 0.0 0.23 11.8 0.0 2.4 2 0 0 2 2 1 0 P21-Rho-binding domain Kin17_mid PF10357.9 CDJ48376.1 - 0.26 11.2 6.6 0.35 10.8 0.2 2.4 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein DUF702 PF05142.12 CDJ48376.1 - 0.4 11.1 9.8 6.1 7.3 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF4770 PF15994.5 CDJ48376.1 - 0.5 10.6 8.9 0.27 11.5 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) TCP PF03634.13 CDJ48376.1 - 0.54 10.8 8.8 0.55 10.8 2.7 2.5 2 0 0 2 2 2 0 TCP family transcription factor Peptidase_S64 PF08192.11 CDJ48376.1 - 0.59 8.6 8.5 0.92 7.9 8.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Activator_LAG-3 PF11498.8 CDJ48376.1 - 0.88 8.5 39.0 0.05 12.6 11.3 2.7 3 0 0 3 3 3 0 Transcriptional activator LAG-3 MAGE PF01454.19 CDJ48376.1 - 1.3 8.7 7.5 1.2 8.8 1.4 2.2 2 0 0 2 2 2 0 MAGE family Methyltransf_34 PF11312.8 CDJ48376.1 - 1.4 8.1 5.3 1.9 7.7 2.8 2.1 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase GREB1 PF15782.5 CDJ48376.1 - 5.1 4.1 14.9 7.4 3.5 14.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Med15 PF09606.10 CDJ48377.1 - 1.5 7.4 58.9 1.9 7.0 58.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.9 CDJ48377.1 - 3.3 5.9 48.9 4.2 5.5 48.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 CDJ48378.1 - 1.7 8.2 34.4 3.1 7.3 34.4 1.4 1 0 0 1 1 1 0 Spt20 family Hid1 PF12722.7 CDJ48378.1 - 2.6 6.0 11.6 3.5 5.6 11.6 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SpoIIIAH PF12685.7 CDJ48379.1 - 0.66 9.8 5.4 1.2 8.9 5.4 1.6 1 1 0 1 1 1 0 SpoIIIAH-like protein SR-25 PF10500.9 CDJ48381.1 - 0.012 15.2 19.8 0.012 15.2 19.8 6.7 4 3 1 5 5 5 0 Nuclear RNA-splicing-associated protein DBINO PF13892.6 CDJ48383.1 - 1.1 9.6 16.2 2.1 8.7 16.2 1.4 1 1 0 1 1 1 0 DNA-binding domain DUF5401 PF17380.2 CDJ48383.1 - 2.2 6.3 11.7 2.8 5.9 11.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4569 PF15133.6 CDJ48383.1 - 4.6 6.9 10.5 5.6 6.6 10.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) SPX PF03105.19 CDJ48384.1 - 0.15 11.9 41.5 0.19 11.6 41.5 1.1 1 0 0 1 1 1 0 SPX domain DUF5349 PF17298.2 CDJ48384.1 - 0.18 11.5 60.3 0.22 11.2 60.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Nop14 PF04147.12 CDJ48384.1 - 0.39 8.9 24.2 0.44 8.7 24.2 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 CDJ48384.1 - 3 7.1 36.0 4 6.7 36.0 1.2 1 0 0 1 1 1 0 BUD22 Utp14 PF04615.13 CDJ48384.1 - 3.5 6.1 37.3 3.8 6.0 37.3 1.0 1 0 0 1 1 1 0 Utp14 protein TSP_1 PF00090.19 CDJ48385.1 - 2.4e-07 30.8 22.3 0.017 15.3 1.9 6.0 4 0 0 4 4 4 4 Thrombospondin type 1 domain MaoC_dehydratas PF01575.19 CDJ48385.1 - 0.11 12.0 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 MaoC like domain TSP_1 PF00090.19 CDJ48386.1 - 0.028 14.7 31.1 0.031 14.5 0.4 4.6 4 1 0 4 4 4 0 Thrombospondin type 1 domain Aconitase PF00330.20 CDJ48387.1 - 5.4e-149 497.1 0.0 7.7e-149 496.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDJ48387.1 - 5.9e-10 39.6 0.0 1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Nsp1_C PF05064.13 CDJ48388.1 - 5.6e-13 48.7 4.3 5.6e-13 48.7 4.3 1.8 2 1 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 CDJ48388.1 - 1.4e-06 29.1 138.1 0.041 14.7 28.3 6.6 1 1 4 5 5 5 1 Nucleoporin FG repeat region PHM7_cyt PF14703.6 CDJ48388.1 - 0.33 11.2 1.1 0.53 10.5 1.1 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Nup88 PF10168.9 CDJ48388.1 - 0.81 7.4 8.1 1.1 7.0 8.1 1.0 1 0 0 1 1 1 0 Nuclear pore component Baculo_PEP_C PF04513.12 CDJ48388.1 - 1.2 9.2 6.1 0.37 10.8 2.6 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CDJ48388.1 - 2.1 8.4 8.8 3.8 7.6 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YkpC PF17447.2 CDJ48388.1 - 9.3 7.4 9.7 74 4.6 0.1 4.9 3 0 0 3 3 3 0 Uncharacterized YkpC-like Pkinase PF00069.25 CDJ48389.1 - 6e-32 111.0 0.0 7.7e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ48389.1 - 3.1e-21 75.8 0.0 4.1e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ48389.1 - 1.4e-10 40.6 0.0 2.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ48389.1 - 0.001 19.0 0.3 0.026 14.4 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family ABC1 PF03109.16 CDJ48389.1 - 0.022 14.9 0.0 0.05 13.8 0.0 1.6 1 1 0 1 1 1 0 ABC1 family Pox_ser-thr_kin PF05445.11 CDJ48389.1 - 0.06 12.3 0.1 0.084 11.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TRAM_LAG1_CLN8 PF03798.16 CDJ48391.1 - 1.7e-10 41.0 4.8 2.3e-10 40.5 4.8 1.2 1 0 0 1 1 1 1 TLC domain Dynamin_M PF01031.20 CDJ48393.1 - 2.2e-58 197.7 0.0 1.1e-55 188.8 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 CDJ48393.1 - 1.7e-52 177.9 0.0 3e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CDJ48393.1 - 1.8e-27 95.3 1.2 5.2e-27 93.8 0.4 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CDJ48393.1 - 2e-06 27.8 0.0 4.9e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 CDJ48393.1 - 0.098 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 CDJ48393.1 - 0.17 12.1 0.6 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ48393.1 - 0.28 11.6 1.5 5.7 7.3 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain Amino_oxidase PF01593.24 CDJ48394.1 - 7.7e-46 157.3 7.8 2.6e-38 132.5 0.1 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase zf-CW PF07496.15 CDJ48394.1 - 3.3e-38 129.5 42.4 2e-13 50.1 9.5 3.8 3 0 0 3 3 3 3 CW-type Zinc Finger NAD_binding_8 PF13450.6 CDJ48394.1 - 1.8e-05 24.8 4.3 1.8e-05 24.8 4.3 3.3 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ48394.1 - 0.0021 17.3 0.3 0.0045 16.3 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ48394.1 - 0.012 14.9 1.6 0.024 13.9 1.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ48394.1 - 0.017 13.8 0.3 0.017 13.8 0.3 3.0 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 CDJ48394.1 - 0.05 12.8 0.5 0.11 11.7 0.5 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 CDJ48394.1 - 0.065 12.3 0.2 0.14 11.2 0.2 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_transf_90 PF05686.12 CDJ48395.1 - 5.3e-62 210.0 0.0 7.9e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Thioredoxin PF00085.20 CDJ48395.1 - 5.5e-31 106.6 0.0 1.9e-14 53.5 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.6 CDJ48395.1 - 2.8e-07 31.0 0.0 0.02 15.3 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDJ48395.1 - 9.1e-07 29.0 0.1 0.047 13.9 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like Glyco_trans_1_2 PF13524.6 CDJ48395.1 - 0.00016 22.0 0.0 0.00037 20.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 AhpC-TSA PF00578.21 CDJ48395.1 - 0.0029 17.5 0.1 5.3 7.0 0.0 3.5 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CDJ48395.1 - 0.003 17.8 0.1 7.7 6.9 0.0 3.5 3 0 0 3 3 3 1 Thioredoxin-like NTP_transf_8 PF12281.8 CDJ48395.1 - 0.042 13.9 0.1 0.12 12.4 0.1 1.6 2 0 0 2 2 2 0 Nucleotidyltransferase Thioredoxin_9 PF14595.6 CDJ48395.1 - 0.049 13.4 0.1 4.3 7.1 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin TraF PF13728.6 CDJ48395.1 - 0.066 13.0 0.1 43 3.8 0.0 3.3 2 1 1 3 3 3 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 CDJ48395.1 - 0.12 12.6 0.1 7.4 6.9 0.0 2.8 2 0 0 2 2 2 0 Glutaredoxin EF-hand_1 PF00036.32 CDJ48397.1 - 9.6e-26 87.4 4.7 6.3e-07 28.5 0.2 4.7 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CDJ48397.1 - 2.6e-23 80.4 2.1 1.7e-06 27.2 0.3 4.9 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CDJ48397.1 - 1.1e-22 80.2 2.8 1.3e-11 44.7 0.5 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ48397.1 - 2.7e-19 67.4 3.5 0.0027 17.5 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDJ48397.1 - 5.2e-11 42.2 7.6 0.00013 21.7 1.2 4.4 4 1 1 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ48397.1 - 1.6e-08 34.9 0.0 0.00067 20.0 0.0 2.5 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region PUB PF09409.10 CDJ48397.1 - 0.00022 21.1 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 PUB domain EF-hand_4 PF12763.7 CDJ48397.1 - 0.0013 18.7 1.8 0.61 10.1 0.3 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CDJ48397.1 - 0.0044 17.2 3.5 0.034 14.3 0.1 3.4 2 1 2 4 4 4 2 Dockerin type I domain EF-hand_9 PF14658.6 CDJ48397.1 - 0.013 15.8 0.1 0.22 11.9 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain Asp PF00026.23 CDJ48398.1 - 1.1e-30 107.2 0.0 2.8e-16 59.8 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ48398.1 - 0.0012 19.2 1.2 0.25 11.6 0.1 3.1 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDJ48398.1 - 0.026 15.2 0.0 6.1 7.6 0.0 3.1 2 1 0 2 2 2 0 Aspartyl protease Ribosomal_60s PF00428.19 CDJ48398.1 - 0.53 10.9 4.9 0.89 10.2 4.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Mito_carr PF00153.27 CDJ48399.1 - 6.9e-32 109.2 2.5 2.8e-13 49.6 0.1 4.0 5 0 0 5 5 5 3 Mitochondrial carrier protein RskA PF10099.9 CDJ48399.1 - 1.5e-05 25.3 14.8 0.0095 16.2 0.4 2.5 2 1 0 2 2 2 2 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ48399.1 - 0.018 15.1 3.1 0.018 15.1 3.1 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ48399.1 - 0.1 12.6 8.3 0.85 9.5 0.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CD20 PF04103.15 CDJ48399.1 - 4.8 7.3 8.3 11 6.1 0.1 2.2 2 0 0 2 2 2 0 CD20-like family Spt20 PF12090.8 CDJ48401.1 - 9.7e-05 22.1 16.2 0.0017 18.0 7.4 2.2 2 0 0 2 2 2 2 Spt20 family TFIIA PF03153.13 CDJ48401.1 - 0.0066 16.5 25.3 0.01 15.9 25.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RB_A PF01858.17 CDJ48401.1 - 0.011 15.6 0.2 0.011 15.6 0.2 1.9 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain DUF2722 PF10846.8 CDJ48401.1 - 0.012 14.6 14.7 0.017 14.1 6.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ48401.1 - 0.014 15.4 0.1 0.014 15.4 0.1 3.2 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Activator_LAG-3 PF11498.8 CDJ48401.1 - 0.27 10.2 27.6 1.2 8.1 13.4 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF4834 PF16118.5 CDJ48401.1 - 0.34 11.9 6.1 6.9 7.7 3.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) WRNPLPNID PF15017.6 CDJ48401.1 - 9.9 7.1 10.1 6.3 7.8 1.3 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DUF2722 PF10846.8 CDJ48402.1 - 0.001 18.1 13.4 0.001 18.1 13.4 14.3 8 4 3 11 11 11 3 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ48402.1 - 0.0026 16.8 24.1 0.0026 16.8 24.1 10.8 9 2 0 9 9 9 3 Transcriptional activator LAG-3 RskA PF10099.9 CDJ48402.1 - 0.003 17.9 37.8 0.004 17.5 17.0 13.2 7 2 3 11 11 11 7 Anti-sigma-K factor rskA Orf78 PF06024.12 CDJ48402.1 - 0.0037 17.5 0.2 0.0037 17.5 0.2 10.8 12 1 0 12 12 12 2 Orf78 (ac78) LAP1C PF05609.12 CDJ48402.1 - 0.0044 16.2 1.4 0.0044 16.2 1.4 10.2 5 3 4 10 10 10 1 Lamina-associated polypeptide 1C (LAP1C) N6_N4_Mtase PF01555.18 CDJ48402.1 - 0.016 14.9 0.0 14 5.3 0.2 4.6 6 1 0 6 6 6 0 DNA methylase DUF2207 PF09972.9 CDJ48402.1 - 0.017 13.9 0.0 0.017 13.9 0.0 4.1 7 0 0 7 7 7 0 Predicted membrane protein (DUF2207) MutS_II PF05188.17 CDJ48403.1 - 0.057 13.7 0.3 0.17 12.2 0.3 1.8 1 0 0 1 1 1 0 MutS domain II FlaC_arch PF05377.11 CDJ48403.1 - 2.3 8.6 6.4 53 4.3 0.0 4.5 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) SUIM_assoc PF16619.5 CDJ48404.1 - 0.056 13.5 0.0 0.056 13.5 0.0 9.3 7 2 0 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 GST_C_3 PF14497.6 CDJ48404.1 - 0.098 12.9 0.0 0.68 10.2 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AP2 PF00847.20 CDJ48406.1 - 0.041 14.1 1.5 0.12 12.6 1.5 1.7 1 0 0 1 1 1 0 AP2 domain IQ PF00612.27 CDJ48411.1 - 0.019 14.7 0.2 0.051 13.4 0.2 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Hydantoinase_B PF02538.14 CDJ48411.1 - 0.59 8.5 6.6 0.86 7.9 6.6 1.3 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase PI_PP_I PF18363.1 CDJ48411.1 - 0.92 9.7 7.5 0.25 11.6 2.2 2.6 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain DUF724 PF05266.14 CDJ48411.1 - 2 8.2 31.9 0.036 13.9 11.4 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Urocanase PF01175.18 CDJ48411.1 - 2.4 7.8 9.6 0.1 12.2 1.8 2.3 2 1 1 3 3 3 0 Urocanase Rossmann-like domain DUF3043 PF11241.8 CDJ48413.1 - 0.00014 22.0 0.6 0.00017 21.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3043) Tim54 PF11711.8 CDJ48413.1 - 0.00042 19.2 2.8 0.00043 19.2 2.8 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 CDJ48413.1 - 0.0055 16.5 1.9 0.0058 16.4 1.9 1.2 1 0 0 1 1 1 1 Connexin EPL1 PF10513.9 CDJ48413.1 - 0.0065 16.9 5.4 0.0065 16.9 5.4 1.1 1 0 0 1 1 1 1 Enhancer of polycomb-like Sporozoite_P67 PF05642.11 CDJ48413.1 - 0.007 14.5 5.0 0.0082 14.3 5.0 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CDC45 PF02724.14 CDJ48413.1 - 0.011 14.1 7.7 0.011 14.0 7.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 CDJ48413.1 - 0.012 15.7 4.7 0.013 15.7 4.7 1.1 1 0 0 1 1 1 0 DDHD domain DUF4770 PF15994.5 CDJ48413.1 - 0.015 15.6 5.7 0.018 15.3 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) MPM1 PF17234.2 CDJ48413.1 - 0.017 15.4 9.5 0.02 15.1 9.5 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Apt1 PF10351.9 CDJ48413.1 - 0.017 14.0 4.8 0.017 14.0 4.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spt20 PF12090.8 CDJ48413.1 - 0.02 14.5 30.0 0.024 14.3 30.0 1.1 1 0 0 1 1 1 0 Spt20 family Eapp_C PF10238.9 CDJ48413.1 - 0.021 14.9 6.1 0.028 14.5 6.1 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF702 PF05142.12 CDJ48413.1 - 0.03 14.8 8.5 0.037 14.5 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Myc_N PF01056.18 CDJ48413.1 - 0.033 14.1 4.6 0.04 13.8 4.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Dynamin_N PF00350.23 CDJ48413.1 - 0.036 14.1 0.8 0.036 14.1 0.8 1.1 1 0 0 1 1 1 0 Dynamin family CAF20 PF17052.5 CDJ48413.1 - 0.039 14.1 8.8 0.06 13.5 8.8 1.3 1 0 0 1 1 1 0 Cap associated factor V_ATPase_I PF01496.19 CDJ48413.1 - 0.043 11.8 5.7 0.041 11.8 5.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 CDJ48413.1 - 0.043 12.8 3.4 0.043 12.8 3.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ALMT PF11744.8 CDJ48413.1 - 0.046 12.6 4.9 0.048 12.5 4.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PPL5 PF18168.1 CDJ48413.1 - 0.047 13.0 3.3 0.052 12.8 3.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 OATP PF03137.20 CDJ48413.1 - 0.055 11.7 1.4 0.061 11.6 1.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SOG2 PF10428.9 CDJ48413.1 - 0.058 12.6 10.7 0.067 12.4 10.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SpoIIP PF07454.11 CDJ48413.1 - 0.064 12.7 9.1 0.068 12.6 9.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 CDJ48413.1 - 0.064 12.0 6.3 0.069 11.9 6.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MMR1 PF08505.10 CDJ48413.1 - 0.078 13.3 13.9 0.09 13.1 13.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CobT PF06213.12 CDJ48413.1 - 0.081 12.3 15.6 0.1 12.0 15.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GREB1 PF15782.5 CDJ48413.1 - 0.082 10.0 9.8 0.088 9.9 9.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5568 PF17724.1 CDJ48413.1 - 0.083 12.7 4.1 0.1 12.4 4.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5568) FAM176 PF14851.6 CDJ48413.1 - 0.086 12.5 7.7 0.11 12.2 7.7 1.2 1 0 0 1 1 1 0 FAM176 family TFIIA PF03153.13 CDJ48413.1 - 0.11 12.5 28.0 0.13 12.2 28.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ48413.1 - 0.13 11.0 12.8 0.14 10.9 12.8 1.1 1 0 0 1 1 1 0 Presenilin BORG_CEP PF14957.6 CDJ48413.1 - 0.13 13.4 9.9 0.14 13.3 9.9 1.1 1 0 0 1 1 1 0 Cdc42 effector RR_TM4-6 PF06459.12 CDJ48413.1 - 0.13 12.0 10.3 0.15 11.9 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2721 PF11026.8 CDJ48413.1 - 0.13 12.1 4.2 0.26 11.2 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) NST1 PF13945.6 CDJ48413.1 - 0.13 12.3 16.1 0.17 11.9 16.1 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Macoilin PF09726.9 CDJ48413.1 - 0.14 10.7 9.0 0.13 10.8 9.0 1.0 1 0 0 1 1 1 0 Macoilin family UPF0560 PF10577.9 CDJ48413.1 - 0.14 10.7 12.3 0.15 10.5 12.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ndc1_Nup PF09531.10 CDJ48413.1 - 0.21 10.3 9.2 0.23 10.1 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4175 PF13779.6 CDJ48413.1 - 0.21 9.5 19.8 0.22 9.4 19.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF755 PF05501.11 CDJ48413.1 - 0.22 11.8 21.9 0.3 11.4 21.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4834 PF16118.5 CDJ48413.1 - 0.24 12.4 16.0 0.45 11.5 16.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) BAF1_ABF1 PF04684.13 CDJ48413.1 - 0.3 10.1 10.9 0.36 9.8 10.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SLC12 PF03522.15 CDJ48413.1 - 0.33 9.9 8.5 0.36 9.8 8.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Rrn6 PF10214.9 CDJ48413.1 - 0.33 9.4 17.3 0.36 9.3 17.3 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4366 PF14283.6 CDJ48413.1 - 0.34 10.9 4.2 0.45 10.5 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PRC2_HTH_1 PF18118.1 CDJ48413.1 - 0.36 11.7 7.8 0.48 11.2 7.8 1.2 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Mem_trans PF03547.18 CDJ48413.1 - 0.38 9.1 2.2 0.43 8.9 2.2 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF4746 PF15928.5 CDJ48413.1 - 0.42 10.0 6.9 0.47 9.8 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) eIF-3_zeta PF05091.12 CDJ48413.1 - 0.44 9.5 15.6 0.5 9.3 15.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4637 PF15470.6 CDJ48413.1 - 0.45 10.2 9.4 0.57 9.9 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Band_3_cyto PF07565.13 CDJ48413.1 - 0.45 10.3 10.3 0.56 10.0 10.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Afi1 PF07792.12 CDJ48413.1 - 0.49 10.9 9.0 0.61 10.6 9.0 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TERB2 PF15101.6 CDJ48413.1 - 0.81 9.7 14.5 0.99 9.4 14.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Sec62 PF03839.16 CDJ48413.1 - 0.91 9.0 5.2 1 8.8 5.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Miga PF10265.9 CDJ48413.1 - 1 8.2 7.9 1.2 8.1 7.9 1.0 1 0 0 1 1 1 0 Mitoguardin Neur_chan_memb PF02932.16 CDJ48413.1 - 1.1 9.3 8.3 1.2 9.1 8.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2126 PF09899.9 CDJ48413.1 - 1.1 7.3 7.1 1.2 7.1 7.1 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) EIIBC-GUT_N PF03612.14 CDJ48413.1 - 1.2 8.9 7.8 1.5 8.5 7.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2828 PF11443.8 CDJ48413.1 - 1.3 7.0 10.6 1.5 6.8 10.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PAT1 PF09770.9 CDJ48413.1 - 1.3 7.2 18.2 1.5 7.0 18.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPSF100_C PF13299.6 CDJ48413.1 - 1.4 9.1 10.1 1.7 8.8 10.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CSG2 PF16965.5 CDJ48413.1 - 1.6 7.6 3.5 1.9 7.4 3.5 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Peptidase_S64 PF08192.11 CDJ48413.1 - 1.7 7.0 10.6 1.9 6.9 10.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3408 PF11888.8 CDJ48413.1 - 1.9 8.6 14.8 3 8.0 14.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) EOS1 PF12326.8 CDJ48413.1 - 2 8.3 5.7 2.5 8.0 5.7 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF4554 PF15091.6 CDJ48413.1 - 2 7.2 11.7 2.6 6.9 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Paf1 PF03985.13 CDJ48413.1 - 2.4 7.1 17.0 2.9 6.8 17.0 1.0 1 0 0 1 1 1 0 Paf1 CLN3 PF02487.17 CDJ48413.1 - 3.2 6.7 8.1 3.8 6.4 8.1 1.1 1 0 0 1 1 1 0 CLN3 protein Lin-8 PF03353.15 CDJ48413.1 - 4 6.9 15.4 4.7 6.7 15.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zip PF02535.22 CDJ48413.1 - 4.2 6.5 6.0 5 6.2 6.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Dicty_REP PF05086.12 CDJ48413.1 - 5.1 5.0 6.3 5.9 4.7 6.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF853 PF05872.12 CDJ48413.1 - 5.9 5.4 12.0 6.9 5.1 12.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Menin PF05053.13 CDJ48413.1 - 6.9 4.9 12.0 8.5 4.6 12.0 1.1 1 0 0 1 1 1 0 Menin Hid1 PF12722.7 CDJ48413.1 - 7.2 4.6 14.5 8.4 4.4 14.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein G0-G1_switch_2 PF15103.6 CDJ48413.1 - 7.9 7.0 12.5 15 6.1 12.5 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 DivIC PF04977.15 CDJ48413.1 - 9.1 6.1 16.6 15 5.4 16.6 1.5 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.9 CDJ48414.1 - 0.00057 18.6 35.9 0.00057 18.6 35.9 2.3 2 1 0 2 2 1 1 Macoilin family TFIIA PF03153.13 CDJ48414.1 - 0.0018 18.3 58.9 0.0018 18.3 58.9 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 CDJ48414.1 - 0.019 13.3 21.4 0.0043 15.4 9.5 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) CDC45 PF02724.14 CDJ48414.1 - 0.044 12.1 23.5 0.043 12.1 22.4 1.6 2 0 0 2 2 2 0 CDC45-like protein MRP-S31 PF15433.6 CDJ48414.1 - 0.16 11.6 32.8 0.27 10.9 32.8 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF2052 PF09747.9 CDJ48414.1 - 0.2 11.8 31.7 0.38 10.9 31.7 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Caldesmon PF02029.15 CDJ48414.1 - 0.26 10.0 37.1 0.41 9.4 37.1 1.3 1 0 0 1 1 1 0 Caldesmon Utp14 PF04615.13 CDJ48414.1 - 0.28 9.7 38.2 0.47 9.0 38.2 1.3 1 0 0 1 1 1 0 Utp14 protein Exonuc_VII_L PF02601.15 CDJ48414.1 - 0.55 9.7 34.3 0.0073 15.9 27.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2126 PF09899.9 CDJ48414.1 - 0.65 8.0 12.3 1.1 7.3 12.3 1.4 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) GLE1 PF07817.13 CDJ48414.1 - 0.99 8.6 33.5 1.8e+04 -6.6 33.3 5.0 1 1 0 1 1 0 0 GLE1-like protein eIF-3_zeta PF05091.12 CDJ48414.1 - 1 8.3 30.6 1.6 7.6 30.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ALMT PF11744.8 CDJ48414.1 - 1.5 7.5 29.5 2.3 6.9 29.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ48414.1 - 5.1 5.2 49.1 7.2 4.7 49.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.11 CDJ48414.1 - 5.2 7.1 29.5 8.2 6.4 29.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Het-C PF07217.11 CDJ48414.1 - 5.2 5.5 14.1 8.9 4.7 14.1 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C eIF-4B PF06273.11 CDJ48414.1 - 5.5 5.9 26.6 0.48 9.4 17.7 2.4 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B Cellulose_synt PF03552.14 CDJ48414.1 - 6.5 5.1 12.0 9.3 4.6 12.0 1.2 1 0 0 1 1 1 0 Cellulose synthase Dicty_REP PF05086.12 CDJ48414.1 - 9.6 4.0 15.5 14 3.5 15.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.13 CDJ48415.1 - 0.0064 16.5 20.3 0.0089 16.1 20.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ48415.1 - 0.71 9.6 8.6 1.3 8.7 0.6 2.3 2 0 0 2 2 2 0 Connexin Activator_LAG-3 PF11498.8 CDJ48415.1 - 1.4 7.8 22.3 2.4 7.0 22.3 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SpoIIP PF07454.11 CDJ48415.1 - 1.7 8.1 15.1 0.2 11.1 1.7 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) ANAPC_CDC26 PF10471.9 CDJ48415.1 - 9.4 7.1 26.9 1.1 10.1 14.5 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 LMBR1 PF04791.16 CDJ48416.1 - 0.00023 20.2 0.7 0.00028 19.9 0.7 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein Lin-8 PF03353.15 CDJ48416.1 - 0.00099 18.8 19.8 0.00099 18.8 19.8 2.9 2 1 0 2 2 2 1 Ras-mediated vulval-induction antagonist DUF4471 PF14740.6 CDJ48416.1 - 0.004 16.4 8.2 0.004 16.4 8.2 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4471) Ecl1 PF12855.7 CDJ48416.1 - 0.0061 17.7 18.1 0.0061 17.7 18.1 2.2 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins SR-25 PF10500.9 CDJ48416.1 - 0.016 14.8 21.2 0.016 14.8 21.2 5.0 3 2 1 4 4 4 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ48416.1 - 0.021 13.7 40.5 0.0053 15.7 12.0 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain CemA PF03040.14 CDJ48416.1 - 0.035 14.0 4.4 0.052 13.5 4.4 1.3 1 0 0 1 1 1 0 CemA family DUF2126 PF09899.9 CDJ48416.1 - 0.29 9.1 9.0 0.43 8.6 9.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SPX PF03105.19 CDJ48416.1 - 2.5 7.9 56.5 0.28 11.1 22.1 2.1 2 0 0 2 2 2 0 SPX domain DUF2052 PF09747.9 CDJ48416.1 - 6.2 6.9 24.0 0.18 11.9 8.6 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF755 PF05501.11 CDJ48417.1 - 0.014 15.7 5.2 0.014 15.7 5.2 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF755) RskA PF10099.9 CDJ48417.1 - 0.015 15.6 10.7 0.015 15.6 10.7 3.4 3 1 0 3 3 3 0 Anti-sigma-K factor rskA Apt1 PF10351.9 CDJ48417.1 - 3.4 6.4 21.5 4 6.2 10.7 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Cadherin_C_2 PF16492.5 CDJ48417.1 - 4.3 8.2 9.0 0.32 11.8 2.2 2.3 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal TFIIA PF03153.13 CDJ48417.1 - 4.4 7.2 32.2 9.5 6.1 32.2 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNF2_N PF00176.23 CDJ48418.1 - 1.5e-35 122.6 0.2 1.2e-18 67.0 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Presenilin PF01080.17 CDJ48418.1 - 0.00019 20.3 9.7 0.00019 20.3 9.7 2.1 2 0 0 2 2 2 1 Presenilin DUF913 PF06025.12 CDJ48418.1 - 0.00038 19.6 3.4 0.00038 19.6 3.4 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DDHD PF02862.17 CDJ48418.1 - 0.00047 20.4 7.8 0.01 16.0 2.6 2.4 2 0 0 2 2 2 1 DDHD domain RloB PF13707.6 CDJ48418.1 - 0.0005 20.3 0.4 0.0005 20.3 0.4 1.8 2 0 0 2 2 2 1 RloB-like protein Pkinase_fungal PF17667.1 CDJ48418.1 - 0.0061 15.4 4.4 0.92 8.2 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase DUF1645 PF07816.11 CDJ48418.1 - 0.018 15.6 11.2 0.018 15.6 11.2 3.1 2 1 0 2 2 1 0 Protein of unknown function (DUF1645) TFIIA PF03153.13 CDJ48418.1 - 0.02 14.9 37.7 0.076 13.0 18.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ48418.1 - 0.089 12.7 31.7 0.1 12.5 8.1 2.1 2 0 0 2 2 2 0 SPX domain AAA_11 PF13086.6 CDJ48418.1 - 0.28 10.9 15.5 0.075 12.8 5.0 2.4 3 0 0 3 3 2 0 AAA domain MID_MedPIWI PF18296.1 CDJ48418.1 - 0.3 10.8 22.6 0.48 10.2 1.8 2.2 2 0 0 2 2 2 0 MID domain of medPIWI PNISR PF15996.5 CDJ48418.1 - 0.5 10.6 33.4 0.16 12.2 17.9 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Apt1 PF10351.9 CDJ48418.1 - 0.51 9.1 23.1 0.43 9.4 6.2 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF572 PF04502.13 CDJ48418.1 - 0.52 9.9 22.2 2.7 7.5 12.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) Cwf_Cwc_15 PF04889.12 CDJ48418.1 - 0.73 9.5 33.5 1.5 8.5 6.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4604 PF15377.6 CDJ48418.1 - 0.92 9.9 24.9 3 8.2 16.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) BPL_N PF09825.9 CDJ48418.1 - 1.4 7.9 10.4 3.3 6.7 10.4 1.5 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF4175 PF13779.6 CDJ48418.1 - 1.6 6.6 39.1 0.61 7.9 22.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Peroxin-3 PF04882.12 CDJ48418.1 - 2.1 7.2 36.7 1.4 7.9 10.5 2.1 2 0 0 2 2 2 0 Peroxin-3 DUF1635 PF07795.11 CDJ48418.1 - 2.5 7.9 28.9 2.1 8.1 5.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Tim54 PF11711.8 CDJ48418.1 - 2.5 6.8 14.4 2.8 6.6 6.5 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CobN-Mg_chel PF02514.16 CDJ48418.1 - 3.2 5.4 11.8 0.12 10.1 6.1 1.4 2 0 0 2 2 2 0 CobN/Magnesium Chelatase FAM60A PF15396.6 CDJ48418.1 - 3.2 7.7 22.4 2.5 8.1 11.3 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF2052 PF09747.9 CDJ48418.1 - 4.3 7.4 27.4 0.86 9.7 13.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Opi1 PF08618.10 CDJ48418.1 - 4.9 6.3 26.9 0.75 9.0 8.3 2.1 2 0 0 2 2 2 0 Transcription factor Opi1 BUD22 PF09073.10 CDJ48418.1 - 4.9 6.4 29.3 0.14 11.5 10.2 2.1 2 0 0 2 2 2 0 BUD22 Plasmodium_Vir PF05795.11 CDJ48418.1 - 5.5 6.3 21.6 5.1 6.4 7.5 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Raftlin PF15250.6 CDJ48418.1 - 5.7 5.6 19.4 5.6 5.6 9.1 2.1 2 0 0 2 2 2 0 Raftlin Macoilin PF09726.9 CDJ48418.1 - 5.9 5.3 23.9 1.3 7.5 5.2 2.2 2 0 0 2 2 2 0 Macoilin family SOG2 PF10428.9 CDJ48418.1 - 6.2 5.9 26.0 2.8 7.0 7.6 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Vfa1 PF08432.10 CDJ48418.1 - 6.4 7.1 24.6 8.1 6.7 1.2 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4667 PF15700.5 CDJ48418.1 - 7.3 6.6 34.9 1 9.4 11.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ48418.1 - 8 6.0 56.1 0.04 13.5 13.0 2.7 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4820 PF16091.5 CDJ48418.1 - 8.2 5.7 26.0 1.4 8.2 12.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4820) TPR_2 PF07719.17 CDJ48419.1 - 4.9e-16 57.5 19.7 0.0012 18.7 0.1 8.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ48419.1 - 1.1e-14 53.5 7.0 0.0019 17.9 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ48419.1 - 3.2e-09 36.2 9.0 0.017 15.1 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ48419.1 - 3.3e-07 30.2 3.7 0.66 10.5 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ48419.1 - 1.1e-05 25.3 10.5 0.0078 16.4 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ48419.1 - 1.5e-05 25.4 3.1 1.5e-05 25.4 3.1 9.5 7 2 1 9 9 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ48419.1 - 3.2e-05 24.1 0.7 3.2e-05 24.1 0.7 6.1 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ48419.1 - 0.00012 22.7 7.3 0.0036 17.9 1.1 12.2 9 3 2 11 11 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ48419.1 - 0.00058 19.5 10.4 0.061 13.0 0.2 4.9 6 0 0 6 6 6 2 TPR repeat Coatomer_E PF04733.14 CDJ48419.1 - 0.0058 16.1 0.2 0.032 13.7 0.1 2.2 2 0 0 2 2 2 1 Coatomer epsilon subunit ANAPC3 PF12895.7 CDJ48419.1 - 0.029 14.6 2.0 0.029 14.6 2.0 4.0 3 1 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CDJ48419.1 - 0.05 13.5 17.1 2.4 8.2 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ48419.1 - 0.059 14.2 0.4 0.059 14.2 0.4 12.7 9 5 5 15 15 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ48419.1 - 1.1 10.0 0.0 1.1 10.0 0.0 8.7 9 0 0 9 9 7 0 Tetratricopeptide repeat ASH PF15780.5 CDJ48420.1 - 1.1e-07 32.0 0.1 5.2e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin N6_N4_Mtase PF01555.18 CDJ48422.1 - 8.3 6.0 0.0 8.3 6.0 0.0 3.4 3 2 0 3 3 3 0 DNA methylase RRM_1 PF00076.22 CDJ48423.1 - 1.4e-08 34.4 0.8 3e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 CDJ48423.1 - 0.0013 18.8 30.8 0.0019 18.3 30.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nup35_RRM_2 PF14605.6 CDJ48423.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif NPR3 PF03666.13 CDJ48424.1 - 0.0083 15.0 14.3 0.01 14.7 14.3 1.0 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 CDJ48424.1 - 0.051 13.3 12.8 0.063 13.0 12.8 1.2 1 0 0 1 1 1 0 Connexin DUF913 PF06025.12 CDJ48424.1 - 0.06 12.3 11.0 0.068 12.1 11.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF908 PF06012.12 CDJ48424.1 - 0.062 12.7 15.3 0.069 12.6 15.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Pex14_N PF04695.13 CDJ48424.1 - 0.075 13.7 30.1 0.098 13.3 30.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIP PF07454.11 CDJ48424.1 - 0.077 12.4 17.4 0.083 12.3 17.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CDJ48424.1 - 0.093 11.5 21.1 0.1 11.4 21.1 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 CDJ48424.1 - 0.099 11.4 13.2 0.11 11.3 13.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3_zeta PF05091.12 CDJ48424.1 - 0.11 11.5 23.8 0.12 11.3 23.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2072 PF09845.9 CDJ48424.1 - 0.13 12.5 13.1 0.16 12.3 13.1 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein RR_TM4-6 PF06459.12 CDJ48424.1 - 0.32 10.8 20.3 0.35 10.6 20.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 CDJ48424.1 - 0.43 8.8 36.8 0.46 8.7 36.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ48424.1 - 0.48 8.7 15.3 0.52 8.6 15.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 CDJ48424.1 - 0.55 9.7 21.6 0.56 9.7 21.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LAP1C PF05609.12 CDJ48424.1 - 0.56 9.2 21.9 0.61 9.1 21.9 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CLN3 PF02487.17 CDJ48424.1 - 0.72 8.8 16.8 0.75 8.8 16.8 1.0 1 0 0 1 1 1 0 CLN3 protein Gti1_Pac2 PF09729.9 CDJ48424.1 - 0.72 9.9 16.7 0.85 9.7 16.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family GPCR_chapero_1 PF11904.8 CDJ48424.1 - 0.89 8.9 11.3 0.87 9.0 11.3 1.0 1 0 0 1 1 1 0 GPCR-chaperone Zip PF02535.22 CDJ48424.1 - 0.92 8.7 7.6 0.96 8.6 7.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 CDJ48424.1 - 0.95 8.4 21.1 0.98 8.4 21.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CSG2 PF16965.5 CDJ48424.1 - 0.98 8.3 11.7 1.2 8.0 11.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Scs3p PF10261.9 CDJ48424.1 - 1.1 8.7 8.1 1.3 8.5 8.1 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2052 PF09747.9 CDJ48424.1 - 1.2 9.2 21.6 1.5 8.9 21.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SLM4 PF16818.5 CDJ48424.1 - 1.3 8.9 22.6 16 5.4 22.6 2.0 1 1 0 1 1 1 0 Protein SLM4 CPSF100_C PF13299.6 CDJ48424.1 - 1.4 9.1 17.4 2 8.5 17.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GET2 PF08690.10 CDJ48424.1 - 1.4 8.5 28.3 1.8 8.2 28.3 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Bul1_N PF04425.12 CDJ48424.1 - 1.6 7.4 16.6 1.7 7.3 16.6 1.0 1 0 0 1 1 1 0 Bul1 N terminus Otopetrin PF03189.13 CDJ48424.1 - 1.7 7.4 11.5 1.9 7.2 11.5 1.1 1 0 0 1 1 1 0 Otopetrin Membralin PF09746.9 CDJ48424.1 - 1.7 7.6 14.6 1.7 7.6 14.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF2370 PF10176.9 CDJ48424.1 - 2.1 8.0 11.4 2.4 7.7 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF2464 PF10240.9 CDJ48424.1 - 2.1 7.8 11.9 2.2 7.8 11.9 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 Ureide_permease PF07168.11 CDJ48424.1 - 2.3 6.9 7.5 2.7 6.7 7.5 1.2 1 0 0 1 1 1 0 Ureide permease Band_3_cyto PF07565.13 CDJ48424.1 - 2.3 8.0 19.2 3.1 7.5 19.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S64 PF08192.11 CDJ48424.1 - 2.3 6.6 17.3 2.7 6.4 17.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2828 PF11443.8 CDJ48424.1 - 2.4 6.2 21.0 2.7 6.0 21.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2126 PF09899.9 CDJ48424.1 - 2.4 6.1 18.5 2.5 6.1 18.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) TFIIA PF03153.13 CDJ48424.1 - 2.4 8.1 52.8 3.2 7.7 52.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HCO3_cotransp PF00955.21 CDJ48424.1 - 2.6 6.8 9.6 2.9 6.6 9.6 1.0 1 0 0 1 1 1 0 HCO3- transporter family PIP5K PF01504.18 CDJ48424.1 - 2.7 7.1 17.5 3.2 6.9 17.5 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CCSAP PF15748.5 CDJ48424.1 - 2.7 8.1 23.4 3 7.9 23.4 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FAM60A PF15396.6 CDJ48424.1 - 3.4 7.6 17.9 4.1 7.3 17.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.16 CDJ48424.1 - 3.9 7.5 18.7 4.2 7.4 18.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ48424.1 - 4 6.2 18.8 4.2 6.1 18.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4471 PF14740.6 CDJ48424.1 - 4.1 6.5 15.0 4.8 6.3 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Endostatin PF06482.11 CDJ48424.1 - 4.2 6.8 23.8 5.3 6.4 23.8 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Cellulose_synt PF03552.14 CDJ48424.1 - 4.5 5.6 8.7 4.8 5.5 8.7 1.1 1 0 0 1 1 1 0 Cellulose synthase Sin_N PF04801.13 CDJ48424.1 - 5.3 6.2 34.1 5.5 6.1 34.1 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Hid1 PF12722.7 CDJ48424.1 - 5.4 5.0 19.1 5.9 4.9 19.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3381 PF11861.8 CDJ48424.1 - 5.7 6.7 29.5 7 6.4 29.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Senescence_reg PF04520.13 CDJ48424.1 - 5.7 7.7 14.8 6.4 7.6 14.8 1.1 1 0 0 1 1 1 0 Senescence regulator Auxin_canalis PF05703.11 CDJ48424.1 - 6 6.7 9.3 6.4 6.6 9.3 1.1 1 0 0 1 1 1 0 Auxin canalisation PepSY_TM PF03929.16 CDJ48424.1 - 6.1 6.4 12.3 9.6 5.8 12.3 1.3 1 0 0 1 1 1 0 PepSY-associated TM region Folliculin PF11704.8 CDJ48424.1 - 6.8 6.5 20.0 7.6 6.4 20.0 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport SUFU_C PF12470.8 CDJ48424.1 - 7.2 6.6 17.6 8.8 6.3 17.6 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain ASC PF00858.24 CDJ48424.1 - 7.4 5.4 11.6 7.7 5.4 11.6 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF4050 PF13259.6 CDJ48424.1 - 8 6.8 18.4 9.8 6.5 18.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) CobT PF06213.12 CDJ48424.1 - 8.6 5.7 31.9 11 5.3 31.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Velvet PF11754.8 CDJ48424.1 - 9.1 6.1 19.8 10 5.9 19.8 1.1 1 0 0 1 1 1 0 Velvet factor PSD3 PF07626.11 CDJ48425.1 - 0.068 13.7 1.0 0.068 13.7 1.0 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1587) PIP5K PF01504.18 CDJ48425.1 - 0.15 11.3 2.5 5 6.3 0.1 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase AAA_23 PF13476.6 CDJ48425.1 - 0.23 12.0 0.0 0.23 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain PAT1 PF09770.9 CDJ48425.1 - 2.6 6.2 34.3 2 6.6 16.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Ctr PF04145.15 CDJ48425.1 - 3.8 8.1 12.9 12 6.5 3.2 3.2 3 0 0 3 3 3 0 Ctr copper transporter family PepSY_TM PF03929.16 CDJ48427.1 - 0.02 14.6 0.0 0.02 14.6 0.0 1.0 1 0 0 1 1 1 0 PepSY-associated TM region DNA_pol_phi PF04931.13 CDJ48427.1 - 2.2 6.3 6.3 2.5 6.1 6.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi RskA PF10099.9 CDJ48428.1 - 0.0061 16.9 17.3 0.0061 16.9 17.3 2.7 1 1 1 2 2 2 1 Anti-sigma-K factor rskA PAT1 PF09770.9 CDJ48428.1 - 0.042 12.1 31.5 0.049 11.9 31.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.7 CDJ48428.1 - 0.063 11.4 15.8 0.074 11.2 15.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDH1_2_SANT_HL1 PF18375.1 CDJ48428.1 - 1.2 9.8 7.1 5.4 7.8 2.8 2.4 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 SARAF PF06682.12 CDJ48428.1 - 1.7 8.2 20.0 0.1 12.2 14.3 1.7 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis ALMT PF11744.8 CDJ48428.1 - 2.1 7.1 13.2 3 6.6 13.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_S49_N PF08496.10 CDJ48428.1 - 3.1 7.8 17.0 0.63 10.1 5.6 2.7 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Exonuc_VII_L PF02601.15 CDJ48428.1 - 4.2 6.8 27.1 6.4 6.3 27.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SLC12 PF03522.15 CDJ48428.1 - 4.4 6.2 17.5 6.2 5.7 17.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF2992 PF11208.8 CDJ48428.1 - 5.9 7.1 23.7 1.8 8.8 10.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) XRN_M PF17846.1 CDJ48428.1 - 6.4 5.6 12.2 9.5 5.1 12.2 1.4 1 0 0 1 1 1 0 Xrn1 helical domain Rtf2 PF04641.12 CDJ48428.1 - 7.5 5.8 24.5 14 5.0 24.3 1.6 1 1 1 2 2 2 0 Rtf2 RING-finger RNA_pol_Rbc25 PF08292.12 CDJ48428.1 - 8.4 6.6 15.7 0.78 10.0 3.7 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Asp_protease_2 PF13650.6 CDJ48430.1 - 3.1e-07 31.0 0.0 7.5e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ48430.1 - 6.2e-05 23.5 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ48430.1 - 0.00041 20.1 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 CDJ48430.1 - 0.0029 17.2 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L22 PF00237.19 CDJ48430.1 - 0.04 14.2 0.1 0.13 12.5 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e RT_RNaseH_2 PF17919.1 CDJ48431.1 - 2.4e-29 101.3 0.2 3.9e-29 100.6 0.2 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ48431.1 - 1.4e-27 96.0 0.2 2.4e-27 95.3 0.2 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ48431.1 - 2.4e-11 43.6 0.1 3.7e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 CDJ48431.1 - 0.0012 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Connexin PF00029.19 CDJ48433.1 - 0.00014 21.7 5.3 0.076 12.8 1.1 2.9 3 0 0 3 3 3 2 Connexin Spt20 PF12090.8 CDJ48433.1 - 0.0019 17.8 19.0 0.0019 17.8 19.0 4.3 4 0 0 4 4 4 2 Spt20 family TMEM51 PF15345.6 CDJ48433.1 - 0.011 15.6 6.8 0.011 15.6 6.8 4.5 5 0 0 5 5 5 0 Transmembrane protein 51 Orf78 PF06024.12 CDJ48433.1 - 0.028 14.7 2.1 0.028 14.7 2.1 3.5 3 0 0 3 3 3 0 Orf78 (ac78) Peroxin-13_N PF04088.13 CDJ48433.1 - 0.029 14.7 2.9 0.029 14.7 2.9 3.9 4 1 0 5 5 4 0 Peroxin 13, N-terminal region tRNA_synt_1c_R2 PF04557.15 CDJ48433.1 - 0.037 14.9 0.7 0.037 14.9 0.7 4.6 5 1 1 6 6 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Mlh1_C PF16413.5 CDJ48433.1 - 0.11 11.8 13.1 0.15 11.4 0.7 3.0 3 0 0 3 3 3 0 DNA mismatch repair protein Mlh1 C-terminus SID-1_RNA_chan PF13965.6 CDJ48433.1 - 0.33 9.3 4.7 3.3 6.0 0.1 2.3 3 0 0 3 3 3 0 dsRNA-gated channel SID-1 DUF2207 PF09972.9 CDJ48433.1 - 0.91 8.2 9.0 2.9 6.5 0.1 3.0 2 1 0 3 3 3 0 Predicted membrane protein (DUF2207) MecA PF05389.12 CDJ48433.1 - 1.1 8.9 21.0 0.13 11.8 2.1 3.3 4 0 0 4 4 4 0 Negative regulator of genetic competence (MecA) AAR2 PF05282.11 CDJ48433.1 - 1.2 8.4 11.4 1.9 7.8 0.5 2.9 3 0 0 3 3 3 0 AAR2 protein PBP1_TM PF14812.6 CDJ48433.1 - 1.4 9.3 9.2 0.74 10.2 0.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 CDJ48433.1 - 1.5 8.5 16.5 0.17 11.6 1.0 3.0 3 0 0 3 3 3 0 FAM176 family Afi1 PF07792.12 CDJ48433.1 - 1.5 9.3 21.3 0.89 10.0 1.2 3.3 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RPA43_OB PF17875.1 CDJ48433.1 - 1.7 9.3 17.5 0.41 11.3 1.0 3.4 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Ni_hydr_CYTB PF01292.20 CDJ48433.1 - 3 7.4 4.9 0.92 9.1 0.1 2.4 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF2127 PF09900.9 CDJ48433.1 - 3.3 8.0 6.5 0.75 10.1 2.5 2.0 2 0 0 2 2 1 0 Predicted membrane protein (DUF2127) SARAF PF06682.12 CDJ48433.1 - 3.8 7.1 42.5 0.16 11.6 7.3 3.2 2 1 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis SpoIIP PF07454.11 CDJ48433.1 - 3.8 6.9 29.1 0.12 11.8 4.2 3.2 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) VKG_Carbox PF05090.14 CDJ48433.1 - 3.8 6.2 8.5 8.1 5.1 3.3 2.9 3 0 0 3 3 3 0 Vitamin K-dependent gamma-carboxylase Rxt3 PF08642.10 CDJ48433.1 - 4.2 8.1 17.8 3 8.6 1.2 3.6 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 SpoIIM PF01944.17 CDJ48433.1 - 4.3 7.4 7.7 1.2 9.2 0.4 3.3 4 0 0 4 4 4 0 Stage II sporulation protein M DUF3464 PF11947.8 CDJ48433.1 - 4.4 7.1 27.5 7.1 6.4 9.3 4.0 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 Glt_symporter PF03616.14 CDJ48433.1 - 6.6 5.3 7.8 2.6 6.7 0.9 2.4 2 0 0 2 2 2 0 Sodium/glutamate symporter DUF4471 PF14740.6 CDJ48433.1 - 7.5 5.7 18.0 0.79 8.9 1.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4471) Exonuc_VII_L PF02601.15 CDJ48434.1 - 1.1 8.8 28.4 2.7 7.5 28.4 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit GREB1 PF15782.5 CDJ48434.1 - 4.9 4.1 45.3 0.035 11.3 29.8 2.2 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer BAF1_ABF1 PF04684.13 CDJ48435.1 - 0.71 8.9 26.0 0.81 8.7 26.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ48435.1 - 2 8.3 39.1 3.2 7.6 39.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3824 PF12868.7 CDJ48435.1 - 2.6 8.7 16.6 0.051 14.3 3.8 2.1 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) SARAF PF06682.12 CDJ48435.1 - 5.3 6.6 28.2 7.8 6.0 28.2 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis GSH_synth_ATP PF03917.17 CDJ48436.1 - 1.6e-56 191.7 17.3 1.1e-53 182.3 17.3 3.8 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CDJ48436.1 - 3.4e-13 49.9 7.5 6e-11 42.7 1.0 3.0 3 0 0 3 3 2 2 Eukaryotic glutathione synthase TFIIA PF03153.13 CDJ48436.1 - 2.6e-05 24.4 24.2 2.6e-05 24.4 24.2 4.3 2 1 2 4 4 2 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ48436.1 - 0.0015 18.2 11.8 0.0015 18.2 11.8 7.3 5 2 1 6 6 4 2 Spt20 family Adaptin_binding PF10199.9 CDJ48436.1 - 0.0034 18.0 0.2 0.0034 18.0 0.2 5.0 3 3 0 3 3 3 1 Alpha and gamma adaptin binding protein p34 SpoIIP PF07454.11 CDJ48436.1 - 0.012 15.0 0.8 0.012 15.0 0.8 3.8 4 1 0 4 4 3 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 CDJ48436.1 - 0.025 13.4 0.2 0.025 13.4 0.2 3.5 3 1 1 4 4 3 0 Inner membrane protein import complex subunit Tim54 Otopetrin PF03189.13 CDJ48436.1 - 0.032 13.0 0.0 0.13 11.0 0.0 2.3 1 1 0 1 1 1 0 Otopetrin FAM60A PF15396.6 CDJ48436.1 - 0.12 12.4 0.1 0.12 12.4 0.1 4.1 4 1 0 4 4 3 0 Protein Family FAM60A JUPITER PF17054.5 CDJ48436.1 - 0.38 10.2 2.9 6.1 6.2 0.4 2.4 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter Cellulose_synt PF03552.14 CDJ48436.1 - 1.9 6.9 7.1 3.5 6.0 7.1 1.3 1 0 0 1 1 1 0 Cellulose synthase PGA_cap PF09587.10 CDJ48436.1 - 7.4 5.9 9.8 25 4.2 0.1 2.8 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap SLX9 PF15341.6 CDJ48438.1 - 0.0004 20.8 7.4 0.0017 18.8 3.5 2.1 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 HAUS6_N PF14661.6 CDJ48438.1 - 0.0016 18.1 12.5 0.0022 17.6 12.5 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus FTCD_C PF04961.12 CDJ48438.1 - 0.013 15.3 3.7 0.013 15.3 3.7 2.1 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase LMBR1 PF04791.16 CDJ48438.1 - 0.13 11.2 4.4 0.15 10.9 4.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1387 PF07139.11 CDJ48438.1 - 3.5 7.3 14.7 4.2 7.0 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) XhlA PF10779.9 CDJ48438.1 - 4.7 7.5 6.4 0.24 11.6 0.7 1.8 2 0 0 2 2 2 0 Haemolysin XhlA RNA_pol_Rbc25 PF08292.12 CDJ48438.1 - 5.4 7.3 9.0 1.2 9.4 0.7 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Rpp20 PF12328.8 CDJ48438.1 - 6.1 6.8 10.3 14 5.6 0.4 2.2 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P DUF2333 PF10095.9 CDJ48438.1 - 6.2 5.7 8.3 2.3 7.2 3.1 2.0 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) Afi1 PF07792.12 CDJ48440.1 - 0.022 15.3 3.1 0.022 15.3 3.1 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Blt1 PF12754.7 CDJ48440.1 - 0.072 13.4 2.3 0.22 11.9 2.3 1.8 1 0 0 1 1 1 0 Blt1 N-terminal domain DUF4683 PF15735.5 CDJ48440.1 - 0.68 9.5 13.9 0.47 10.0 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4683) RNA_pol_Rpc4 PF05132.14 CDJ48440.1 - 0.76 10.2 25.0 0.72 10.3 9.7 2.5 3 0 0 3 3 3 0 RNA polymerase III RPC4 RskA PF10099.9 CDJ48440.1 - 6.3 7.0 32.6 5.4 7.3 1.9 3.1 1 1 2 3 3 3 0 Anti-sigma-K factor rskA MOZART1 PF12554.8 CDJ48441.1 - 1.1e-19 69.9 1.5 1.7e-19 69.3 1.5 1.3 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated p450 PF00067.22 CDJ48441.1 - 0.012 14.4 0.1 0.012 14.4 0.1 1.0 1 0 0 1 1 1 0 Cytochrome P450 Tubulin PF00091.25 CDJ48442.1 - 3.2e-68 229.8 0.0 6.1e-68 228.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ48442.1 - 3e-42 143.8 0.0 4.5e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDJ48442.1 - 0.00028 21.2 0.0 0.00073 19.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CDJ48442.1 - 0.0053 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 CDJ48442.1 - 0.0066 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain YjbE PF11106.8 CDJ48443.1 - 2.7 8.3 14.6 3 8.1 3.6 3.2 3 0 0 3 3 3 0 Exopolysaccharide production protein YjbE KASH_CCD PF14662.6 CDJ48444.1 - 0.16 11.8 8.3 3 7.6 0.4 2.5 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 CDJ48444.1 - 2 8.5 10.5 3.9 7.6 1.8 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CDJ48444.1 - 3.2 6.5 9.7 5.8 5.7 9.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Hydrolase PF00702.26 CDJ48445.1 - 1.5e-06 28.6 0.0 7.5e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 CDJ48445.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Acid Phosphatase RskA PF10099.9 CDJ48445.1 - 0.29 11.4 10.4 0.47 10.7 10.4 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Mcl1_mid PF12341.8 CDJ48446.1 - 7.3e-25 87.9 0.0 1.3e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region BAF1_ABF1 PF04684.13 CDJ48446.1 - 2 7.4 9.9 0.66 9.0 2.3 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Dynactin_p62 PF05502.13 CDJ48447.1 - 0.36 9.6 6.8 0.69 8.6 6.8 1.4 1 0 0 1 1 1 0 Dynactin p62 family SR-25 PF10500.9 CDJ48448.1 - 0.003 17.2 33.7 0.003 17.2 33.7 4.3 2 1 0 3 3 3 2 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ48449.1 - 0.68 10.0 0.0 0.68 10.0 0.0 18.9 9 6 5 14 14 14 0 Unstructured region C-term to UIM in Ataxin3 AARP2CN PF08142.12 CDJ48449.1 - 6.1 7.0 8.9 11 6.2 0.3 3.6 3 1 0 3 3 3 0 AARP2CN (NUC121) domain DUF1645 PF07816.11 CDJ48452.1 - 0.19 12.3 22.5 0.051 14.2 12.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF572 PF04502.13 CDJ48452.1 - 0.44 10.1 18.7 0.59 9.7 18.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3138 PF11336.8 CDJ48455.1 - 0.62 8.6 12.0 0.62 8.6 12.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2057 PF09829.9 CDJ48455.1 - 0.91 9.7 7.3 1 9.5 7.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF3450 PF11932.8 CDJ48455.1 - 1.6 8.0 10.6 1.8 7.8 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RskA PF10099.9 CDJ48455.1 - 2 8.6 15.0 2.6 8.3 15.0 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ48455.1 - 2.2 8.8 6.8 3 8.4 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) SR-25 PF10500.9 CDJ48456.1 - 0.071 12.7 38.7 0.78 9.3 38.8 2.0 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein V_ATPase_I PF01496.19 CDJ48456.1 - 0.29 9.0 28.5 0.014 13.3 13.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NMDAR2_C PF10565.9 CDJ48456.1 - 0.88 8.4 31.0 1 8.1 31.0 1.0 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus SPX PF03105.19 CDJ48456.1 - 4.6 7.1 36.4 6.8 6.5 36.4 1.2 1 0 0 1 1 1 0 SPX domain Peptidase_S49_N PF08496.10 CDJ48456.1 - 6 6.9 27.1 3.4 7.7 13.5 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Methyltransf_32 PF13679.6 CDJ48456.1 - 6.2 6.8 24.9 0.27 11.2 11.4 2.2 2 0 0 2 2 2 0 Methyltransferase domain PI3K_1B_p101 PF10486.9 CDJ48456.1 - 6.2 4.5 30.5 7.2 4.3 30.0 1.3 1 1 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Hid1 PF12722.7 CDJ48456.1 - 7.2 4.6 33.8 11 4.1 33.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCDC84 PF14968.6 CDJ48456.1 - 7.5 6.1 36.0 8.9 5.8 36.0 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 DUF5308 PF17233.2 CDJ48457.1 - 0.071 13.3 7.2 0.084 13.1 7.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) eIF-3_zeta PF05091.12 CDJ48457.1 - 0.092 11.7 13.1 0.087 11.8 13.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4746 PF15928.5 CDJ48457.1 - 0.1 12.0 7.8 0.11 11.9 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF5523 PF17661.1 CDJ48457.1 - 0.11 12.2 12.8 0.12 12.0 12.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DDHD PF02862.17 CDJ48457.1 - 0.14 12.3 5.9 0.13 12.4 5.9 1.2 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.13 CDJ48457.1 - 0.25 10.3 14.4 0.24 10.4 14.4 1.1 1 0 0 1 1 1 0 Paf1 SpoIIP PF07454.11 CDJ48457.1 - 0.27 10.7 10.3 0.31 10.5 10.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF1980 PF09323.10 CDJ48457.1 - 0.36 10.7 4.4 0.34 10.8 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Spt20 PF12090.8 CDJ48457.1 - 0.39 10.3 33.6 0.61 9.7 33.6 1.3 1 0 0 1 1 1 0 Spt20 family U79_P34 PF03064.16 CDJ48457.1 - 0.4 10.0 8.9 0.45 9.8 8.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Presenilin PF01080.17 CDJ48457.1 - 0.42 9.3 11.8 0.39 9.4 11.8 1.1 1 0 0 1 1 1 0 Presenilin DUF3408 PF11888.8 CDJ48457.1 - 0.49 10.5 10.3 0.76 9.9 10.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) EOS1 PF12326.8 CDJ48457.1 - 0.53 10.2 1.5 0.52 10.2 1.5 1.2 1 0 0 1 1 1 0 N-glycosylation protein Coilin_N PF15862.5 CDJ48457.1 - 0.54 10.0 10.4 0.77 9.6 10.4 1.3 1 0 0 1 1 1 0 Coilin N-terminus CDC45 PF02724.14 CDJ48457.1 - 0.59 8.3 9.5 0.63 8.3 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein V_ATPase_I PF01496.19 CDJ48457.1 - 0.62 7.9 8.4 0.62 7.9 8.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 CDJ48457.1 - 0.71 9.7 15.0 0.83 9.4 15.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rxt3 PF08642.10 CDJ48457.1 - 0.74 10.6 4.2 0.95 10.2 4.2 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Connexin PF00029.19 CDJ48457.1 - 0.76 9.5 4.8 0.69 9.6 4.8 1.1 1 0 0 1 1 1 0 Connexin SLC12 PF03522.15 CDJ48457.1 - 1.2 8.1 7.6 1.1 8.2 7.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 CDJ48457.1 - 1.3 7.1 10.4 1.1 7.3 10.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.6 CDJ48457.1 - 1.4 8.2 7.5 1.4 8.2 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1387 PF07139.11 CDJ48457.1 - 1.5 8.5 12.0 1.6 8.4 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF4834 PF16118.5 CDJ48457.1 - 1.6 9.7 13.3 3.4 8.7 13.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3729 PF12526.8 CDJ48457.1 - 1.8 10.1 9.1 2.7 9.6 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) Neur_chan_memb PF02932.16 CDJ48457.1 - 2.2 8.3 8.9 2.4 8.2 8.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF913 PF06025.12 CDJ48457.1 - 2.4 7.0 7.0 2.5 7.0 7.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Suf PF05843.14 CDJ48457.1 - 2.6 8.0 15.6 3.1 7.7 15.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 CDJ48457.1 - 2.8 6.1 20.9 2.9 6.0 20.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.6 CDJ48457.1 - 2.9 5.7 30.2 3 5.6 30.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4551 PF15087.6 CDJ48457.1 - 3.7 6.3 9.8 4 6.1 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TFIIA PF03153.13 CDJ48457.1 - 3.7 7.4 32.3 4.3 7.2 32.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 CDJ48457.1 - 4.2 6.7 25.4 0.48 9.8 21.5 1.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Zip PF02535.22 CDJ48457.1 - 6.1 6.0 5.9 5.8 6.0 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 CDJ48457.1 - 6.4 5.5 13.5 8 5.1 13.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Plasmodium_Vir PF05795.11 CDJ48457.1 - 6.8 6.0 7.7 7.4 5.9 7.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PBP1_TM PF14812.6 CDJ48457.1 - 7.5 7.0 11.2 15 6.1 11.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4407 PF14362.6 CDJ48458.1 - 0.013 14.9 23.4 0.017 14.5 23.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tim54 PF11711.8 CDJ48458.1 - 0.018 13.9 20.2 0.023 13.5 20.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 CDJ48458.1 - 0.022 13.8 11.9 0.025 13.5 11.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Raftlin PF15250.6 CDJ48458.1 - 0.038 12.8 19.1 0.041 12.6 19.1 1.0 1 0 0 1 1 1 0 Raftlin WTX PF09422.10 CDJ48458.1 - 0.057 12.5 15.5 0.062 12.4 15.5 1.0 1 0 0 1 1 1 0 WTX protein DDRGK PF09756.9 CDJ48458.1 - 0.085 12.4 34.0 0.1 12.2 34.0 1.1 1 0 0 1 1 1 0 DDRGK domain UPF0565 PF10561.9 CDJ48458.1 - 0.1 11.8 9.3 0.13 11.5 9.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 GREB1 PF15782.5 CDJ48458.1 - 0.12 9.4 26.3 0.14 9.3 26.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2828 PF11443.8 CDJ48458.1 - 0.14 10.2 23.9 0.16 10.1 23.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Velvet PF11754.8 CDJ48458.1 - 0.22 11.4 25.7 0.3 11.0 25.7 1.2 1 0 0 1 1 1 0 Velvet factor SLC12 PF03522.15 CDJ48458.1 - 0.24 10.4 28.7 0.26 10.3 28.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ48458.1 - 0.34 9.6 36.9 0.4 9.4 36.9 1.0 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 CDJ48458.1 - 0.37 9.2 25.2 0.42 9.0 25.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Zip PF02535.22 CDJ48458.1 - 0.49 9.6 14.9 0.53 9.5 14.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 CDJ48458.1 - 0.52 8.5 26.1 0.6 8.3 26.1 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ48458.1 - 0.59 9.9 32.9 0.69 9.7 32.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ48458.1 - 0.59 10.1 22.0 0.74 9.8 22.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hamartin PF04388.12 CDJ48458.1 - 0.83 8.2 23.9 0.86 8.2 23.9 1.0 1 0 0 1 1 1 0 Hamartin protein Endostatin PF06482.11 CDJ48458.1 - 0.89 9.0 28.7 0.99 8.8 28.7 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF3807 PF12720.7 CDJ48458.1 - 1 9.6 37.3 1.4 9.2 37.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) PTPRCAP PF15713.5 CDJ48458.1 - 1.3 9.3 31.9 1.6 9.0 31.9 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated MCD PF05292.11 CDJ48458.1 - 1.4 8.5 12.8 1.8 8.0 12.8 1.2 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain DUF4746 PF15928.5 CDJ48458.1 - 1.7 8.0 21.4 2.1 7.7 21.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CCSAP PF15748.5 CDJ48458.1 - 1.7 8.8 34.9 2 8.5 34.9 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CSG2 PF16965.5 CDJ48458.1 - 1.7 7.5 15.3 2.2 7.1 15.3 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator V_ATPase_I PF01496.19 CDJ48458.1 - 1.8 6.4 29.1 2.2 6.1 29.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HCO3_cotransp PF00955.21 CDJ48458.1 - 1.8 7.3 11.1 1.9 7.2 11.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family Vfa1 PF08432.10 CDJ48458.1 - 1.8 8.8 30.4 2.3 8.5 30.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Plasmodium_Vir PF05795.11 CDJ48458.1 - 2.1 7.7 15.5 2.4 7.5 15.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LAP1C PF05609.12 CDJ48458.1 - 2.5 7.1 27.5 2.6 7.0 27.5 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4569 PF15133.6 CDJ48458.1 - 2.6 7.7 29.4 3 7.5 29.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Gti1_Pac2 PF09729.9 CDJ48458.1 - 2.6 8.1 24.4 3.6 7.7 24.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Pox_Ag35 PF03286.14 CDJ48458.1 - 2.7 7.7 16.8 3.2 7.5 16.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MDFI PF15316.6 CDJ48458.1 - 3 7.9 16.2 3.5 7.7 16.2 1.2 1 0 0 1 1 1 0 MyoD family inhibitor DUF2151 PF10221.9 CDJ48458.1 - 3.5 6.1 16.0 3.9 6.0 16.0 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator NARP1 PF12569.8 CDJ48458.1 - 3.9 6.3 26.0 4.8 6.0 26.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NPR3 PF03666.13 CDJ48458.1 - 4.6 5.9 30.9 5.9 5.6 30.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PAT1 PF09770.9 CDJ48458.1 - 4.9 5.3 54.0 5.7 5.1 54.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.9 CDJ48458.1 - 5.2 5.8 21.1 5.8 5.7 21.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAPS PF04499.15 CDJ48458.1 - 5.4 5.7 22.3 6 5.5 22.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CAC1F_C PF16885.5 CDJ48458.1 - 5.5 6.5 20.6 5.8 6.5 20.6 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term PPL5 PF18168.1 CDJ48458.1 - 6 6.1 19.6 8.9 5.5 19.6 1.3 1 0 0 1 1 1 0 Prim-pol family 5 ALMT PF11744.8 CDJ48458.1 - 6.2 5.5 25.1 6.8 5.4 25.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4045 PF13254.6 CDJ48458.1 - 6.4 6.3 27.7 7.2 6.1 27.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Pkinase_fungal PF17667.1 CDJ48458.1 - 6.6 5.4 14.8 7.7 5.2 14.8 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF2370 PF10176.9 CDJ48458.1 - 7 6.2 16.5 9.7 5.8 16.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Neur_chan_memb PF02932.16 CDJ48458.1 - 7.3 6.6 26.1 8.4 6.4 26.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ48458.1 - 7.8 6.2 28.4 12 5.6 28.4 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pannexin_like PF12534.8 CDJ48458.1 - 8.2 5.4 21.6 11 4.9 21.6 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Otopetrin PF03189.13 CDJ48458.1 - 8.4 5.1 16.3 10 4.8 16.3 1.2 1 0 0 1 1 1 0 Otopetrin eIF-3_zeta PF05091.12 CDJ48458.1 - 8.8 5.2 41.2 12 4.7 41.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AF-4 PF05110.13 CDJ48459.1 - 6.1e-06 24.7 25.7 7.9e-06 24.3 25.7 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Pkinase PF00069.25 CDJ48459.1 - 0.00014 21.3 0.0 0.00014 21.3 0.0 2.1 2 0 0 2 2 1 1 Protein kinase domain TFIIA PF03153.13 CDJ48459.1 - 0.0041 17.2 40.7 0.0049 16.9 40.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 CDJ48459.1 - 0.0086 16.1 10.9 0.0086 16.1 10.9 2.1 1 1 1 2 2 2 1 Protein Family FAM60A CCSAP PF15748.5 CDJ48459.1 - 0.034 14.3 24.9 0.042 14.0 24.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FHIPEP PF00771.20 CDJ48459.1 - 0.043 12.3 2.8 0.054 12.0 2.8 1.3 1 0 0 1 1 1 0 FHIPEP family Med15 PF09606.10 CDJ48459.1 - 0.057 12.1 36.0 0.069 11.8 36.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hamartin PF04388.12 CDJ48459.1 - 0.083 11.5 18.4 0.1 11.3 18.4 1.1 1 0 0 1 1 1 0 Hamartin protein eIF-3_zeta PF05091.12 CDJ48459.1 - 0.087 11.8 12.4 0.088 11.8 12.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Radical_SAM_N PF08497.10 CDJ48459.1 - 0.19 11.0 5.2 0.19 10.9 5.2 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal SprA-related PF12118.8 CDJ48459.1 - 0.27 10.3 37.9 0.36 9.9 37.9 1.1 1 0 0 1 1 1 0 SprA-related family RAP1 PF07218.11 CDJ48459.1 - 0.35 9.1 7.2 0.41 8.9 7.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.9 CDJ48459.1 - 0.64 8.2 29.6 0.72 8.1 29.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SelP_N PF04592.14 CDJ48459.1 - 0.81 9.0 27.9 0.046 13.1 22.7 1.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF4241 PF14025.6 CDJ48459.1 - 1.4 9.1 4.8 4.7 7.4 4.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4241) BAF1_ABF1 PF04684.13 CDJ48459.1 - 2.9 6.9 24.1 4.1 6.4 24.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor YlqD PF11068.8 CDJ48459.1 - 3.1 8.2 26.1 4.8 7.6 26.1 1.3 1 0 0 1 1 1 0 YlqD protein Secretin_N_2 PF07655.13 CDJ48459.1 - 4.2 8.0 19.9 2.4 8.8 10.0 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Connexin PF00029.19 CDJ48459.1 - 4.5 7.0 11.6 0.44 10.3 7.4 1.5 2 0 0 2 2 2 0 Connexin Serinc PF03348.15 CDJ48459.1 - 4.6 6.1 9.3 5.8 5.7 9.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1764 PF08576.10 CDJ48459.1 - 5.9 7.9 13.1 1.8 9.5 7.1 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) CCDC14 PF15254.6 CDJ48459.1 - 7.8 5.0 27.1 10 4.6 27.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Lin-8 PF03353.15 CDJ48459.1 - 9 5.8 27.4 0.65 9.5 13.7 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist LAP1C PF05609.12 CDJ48459.1 - 9.3 5.2 24.2 11 4.9 24.2 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SOG2 PF10428.9 CDJ48459.1 - 9.8 5.2 28.0 15 4.6 28.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CDC45 PF02724.14 CDJ48460.1 - 0.016 13.6 30.5 0.018 13.4 30.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ48460.1 - 0.069 11.9 47.1 0.085 11.6 47.1 1.1 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 CDJ48460.1 - 0.19 11.3 30.8 0.24 11.0 30.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Smg8_Smg9 PF10220.9 CDJ48460.1 - 0.22 9.8 32.7 0.24 9.7 32.7 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Raftlin PF15250.6 CDJ48460.1 - 0.36 9.5 30.3 0.4 9.4 30.3 1.1 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 CDJ48460.1 - 0.44 9.5 40.0 0.51 9.3 40.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Apt1 PF10351.9 CDJ48460.1 - 1 8.1 27.8 1.2 7.9 27.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Exonuc_VII_L PF02601.15 CDJ48460.1 - 1.4 8.4 40.5 1.6 8.2 40.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4045 PF13254.6 CDJ48460.1 - 1.5 8.4 37.7 1.8 8.2 37.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) LAP1C PF05609.12 CDJ48460.1 - 2.9 6.9 40.2 3 6.8 40.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2052 PF09747.9 CDJ48460.1 - 3.3 7.8 41.4 5.1 7.2 41.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Membralin PF09746.9 CDJ48460.1 - 4.7 6.1 24.9 6 5.8 24.9 1.2 1 0 0 1 1 1 0 Tumour-associated protein Macoilin PF09726.9 CDJ48460.1 - 6.2 5.3 35.0 7.8 4.9 35.0 1.0 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 CDJ48460.1 - 6.8 6.5 33.4 8.4 6.2 33.4 1.1 1 0 0 1 1 1 0 SPX domain PA26 PF04636.13 CDJ48460.1 - 8.1 5.2 30.0 9.6 5.0 30.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Draxin PF15550.6 CDJ48460.1 - 8.3 6.2 29.0 10 5.9 29.0 1.1 1 0 0 1 1 1 0 Draxin RR_TM4-6 PF06459.12 CDJ48461.1 - 0.12 12.2 30.6 0.15 11.9 30.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CSG2 PF16965.5 CDJ48461.1 - 0.36 9.7 10.8 0.36 9.7 10.8 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Zip PF02535.22 CDJ48461.1 - 0.47 9.6 13.8 0.52 9.5 13.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter VIR_N PF15912.5 CDJ48461.1 - 0.59 9.7 25.3 0.72 9.4 25.3 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal Hamartin PF04388.12 CDJ48461.1 - 1 7.9 30.3 1.2 7.7 30.3 1.0 1 0 0 1 1 1 0 Hamartin protein Serinc PF03348.15 CDJ48461.1 - 1.3 7.8 16.0 1.5 7.6 16.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Cellulose_synt PF03552.14 CDJ48461.1 - 1.6 7.1 10.5 1.9 6.9 10.5 1.0 1 0 0 1 1 1 0 Cellulose synthase NPR3 PF03666.13 CDJ48461.1 - 1.9 7.2 27.2 2.2 7.0 27.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ48461.1 - 3.5 6.3 36.0 4.1 6.1 36.0 1.1 1 0 0 1 1 1 0 Presenilin Dishevelled PF02377.15 CDJ48461.1 - 3.5 8.1 20.0 4.5 7.7 20.0 1.2 1 0 0 1 1 1 0 Dishevelled specific domain DUF5523 PF17661.1 CDJ48461.1 - 4.5 6.9 30.5 6.2 6.4 30.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Endostatin PF06482.11 CDJ48461.1 - 4.7 6.6 29.2 6 6.2 29.2 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SID-1_RNA_chan PF13965.6 CDJ48461.1 - 5.6 5.3 13.1 6.3 5.1 13.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 XRN_M PF17846.1 CDJ48461.1 - 7 5.5 18.9 9 5.1 18.9 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Hid1 PF12722.7 CDJ48461.1 - 7.8 4.5 33.1 8.3 4.4 33.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Membralin PF09746.9 CDJ48461.1 - 8.4 5.3 16.6 9.7 5.1 16.6 1.2 1 0 0 1 1 1 0 Tumour-associated protein HCO3_cotransp PF00955.21 CDJ48461.1 - 8.7 5.0 11.5 8.8 5.0 11.5 1.1 1 0 0 1 1 1 0 HCO3- transporter family Ureide_permease PF07168.11 CDJ48461.1 - 8.9 5.0 12.3 12 4.6 12.3 1.3 1 0 0 1 1 1 0 Ureide permease AAA_11 PF13086.6 CDJ48461.1 - 9.7 5.9 26.7 12 5.6 26.7 1.1 1 0 0 1 1 1 0 AAA domain RskA PF10099.9 CDJ48462.1 - 0.00058 20.2 18.8 0.00097 19.5 18.8 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Activator_LAG-3 PF11498.8 CDJ48462.1 - 0.022 13.7 15.6 0.033 13.2 15.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ldi PF18566.1 CDJ48462.1 - 0.74 9.2 3.6 1.1 8.7 3.6 1.2 1 0 0 1 1 1 0 Linalool dehydratase/isomerase Med3 PF11593.8 CDJ48462.1 - 0.76 8.9 17.1 1.1 8.4 17.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sec16 PF12932.7 CDJ48463.1 - 0.16 12.6 4.7 0.22 12.1 4.7 1.3 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Trp_oprn_chp PF09534.10 CDJ48463.1 - 0.27 11.0 10.8 0.31 10.8 10.8 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ribosomal_60s PF00428.19 CDJ48463.1 - 0.29 11.8 11.2 0.4 11.3 11.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein BAF1_ABF1 PF04684.13 CDJ48463.1 - 2.9 6.8 18.2 3.3 6.7 18.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor BAT2_N PF07001.11 CDJ48463.1 - 3.2 8.2 23.0 3.9 7.9 23.0 1.1 1 0 0 1 1 1 0 BAT2 N-terminus RskA PF10099.9 CDJ48463.1 - 6.7 7.0 25.6 16 5.7 25.6 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ48464.1 - 0.41 10.9 18.6 0.59 10.4 18.6 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SPX PF03105.19 CDJ48465.1 - 4.5 7.1 45.7 0.027 14.4 19.9 2.1 1 1 1 2 2 2 0 SPX domain DUF2722 PF10846.8 CDJ48466.1 - 0.00053 19.1 4.4 0.00053 19.1 4.4 2.6 2 0 0 2 2 1 1 Protein of unknown function (DUF2722) Spore_YhcN_YlaJ PF09580.10 CDJ48466.1 - 0.00077 19.6 1.9 0.1 12.7 0.1 2.3 2 0 0 2 2 2 2 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Eapp_C PF10238.9 CDJ48466.1 - 0.49 10.5 13.4 2.3 8.3 6.0 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein EOS1 PF12326.8 CDJ48466.1 - 0.62 10.0 4.7 4.4 7.2 0.4 2.3 2 0 0 2 2 2 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ48466.1 - 2.2 7.1 26.5 1.9 7.4 10.5 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Thg1C PF14413.6 CDJ48466.1 - 2.5 8.3 13.6 5.5 7.2 5.4 2.5 2 0 0 2 2 2 0 Thg1 C terminal domain Neur_chan_memb PF02932.16 CDJ48466.1 - 3.9 7.5 13.8 4.8 7.2 1.5 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PIP5K PF01504.18 CDJ48466.1 - 4.9 6.3 13.1 8.3 5.5 6.8 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Dynamin_N PF00350.23 CDJ48466.1 - 5.5 7.0 8.7 0.95 9.5 3.0 2.2 2 0 0 2 2 2 0 Dynamin family SpoIIP PF07454.11 CDJ48466.1 - 6.4 6.1 17.4 8.7 5.7 8.6 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) MecA PF05389.12 CDJ48466.1 - 6.7 6.3 12.9 8.8 5.9 1.2 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) PAT1 PF09770.9 CDJ48466.1 - 7.8 4.6 33.7 1.9 6.6 12.0 2.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CIAPIN1 PF05093.13 CDJ48466.1 - 9.7 6.8 12.3 27 5.4 0.2 2.8 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis TTL PF03133.15 CDJ48467.1 - 1.3e-29 103.3 0.2 1.3e-29 103.3 0.2 4.0 4 1 1 5 5 5 1 Tubulin-tyrosine ligase family Spt20 PF12090.8 CDJ48467.1 - 0.00096 18.8 8.6 0.00096 18.8 8.6 13.3 8 3 2 11 11 11 2 Spt20 family MMS1_N PF10433.9 CDJ48469.1 - 1.4e-60 205.4 0.0 3.9e-60 203.9 0.0 1.7 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Neur_chan_memb PF02932.16 CDJ48469.1 - 0.11 12.5 6.8 0.18 11.8 1.8 2.7 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 CDJ48469.1 - 0.3 10.0 48.6 0.23 10.4 3.3 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ48469.1 - 0.38 10.3 67.8 0.033 13.8 3.6 4.1 4 0 0 4 4 4 0 Spt20 family DUF4834 PF16118.5 CDJ48469.1 - 0.74 10.8 27.6 0.55 11.2 1.2 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) MecA PF05389.12 CDJ48469.1 - 2.1 8.0 7.4 1.9 8.1 1.1 3.2 4 0 0 4 4 4 0 Negative regulator of genetic competence (MecA) CCDC53 PF10152.9 CDJ48469.1 - 9.9 6.6 27.8 0.44 11.0 10.1 3.4 3 1 0 3 3 3 0 Subunit CCDC53 of WASH complex IHABP4_N PF16174.5 CDJ48470.1 - 7.9 7.1 25.9 9 6.9 25.9 1.0 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal YABBY PF04690.13 CDJ48470.1 - 9.6 6.7 17.8 9.8 6.7 17.8 1.0 1 0 0 1 1 1 0 YABBY protein CDC27 PF09507.10 CDJ48471.1 - 0.0019 17.6 54.5 0.0027 17.2 54.5 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Hamartin PF04388.12 CDJ48471.1 - 0.25 10.0 49.2 0.31 9.7 49.2 1.0 1 0 0 1 1 1 0 Hamartin protein FA_desaturase PF00487.24 CDJ48471.1 - 0.31 10.8 3.0 0.52 10.1 3.0 1.4 1 0 0 1 1 1 0 Fatty acid desaturase RskA PF10099.9 CDJ48473.1 - 0.0095 16.2 11.9 0.0095 16.2 11.9 6.0 2 2 2 4 4 4 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ48473.1 - 5.2 6.6 67.3 0.016 14.9 13.1 4.3 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein DUF2681 PF10883.8 CDJ48475.1 - 0.0031 17.9 0.4 0.0086 16.5 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) TFIIA PF03153.13 CDJ48475.1 - 6.8 6.6 28.4 10 6.0 28.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serpulina_VSP PF05540.11 CDJ48476.1 - 0.11 11.5 1.2 0.52 9.3 1.2 2.2 1 1 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein Corona_NS3b PF03053.14 CDJ48476.1 - 1.1 8.9 0.0 1.1 8.9 0.0 2.8 3 0 0 3 3 3 0 ORF3b coronavirus protein SID-1_RNA_chan PF13965.6 CDJ48477.1 - 0.0023 16.4 6.6 0.0029 16.1 6.6 1.3 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 BAF1_ABF1 PF04684.13 CDJ48477.1 - 0.0042 16.2 22.8 0.0051 15.9 22.8 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Rrn6 PF10214.9 CDJ48477.1 - 0.069 11.6 51.7 0.11 11.0 51.7 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RR_TM4-6 PF06459.12 CDJ48477.1 - 0.24 11.2 36.7 0.5 10.1 36.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 CDJ48477.1 - 0.91 9.8 30.8 1.7 8.9 30.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Isy1 PF06246.12 CDJ48477.1 - 6.6 6.2 36.8 11 5.5 36.8 1.2 1 0 0 1 1 1 0 Isy1-like splicing family CLN3 PF02487.17 CDJ48478.1 - 0.35 9.9 2.9 0.38 9.8 2.9 1.1 1 0 0 1 1 1 0 CLN3 protein CPSF100_C PF13299.6 CDJ48478.1 - 0.36 11.0 0.1 0.36 11.0 0.1 2.1 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 CDJ48478.1 - 0.48 10.2 2.8 0.61 9.8 2.8 1.2 1 0 0 1 1 1 0 Connexin RskA PF10099.9 CDJ48478.1 - 0.97 9.7 27.3 11 6.2 27.2 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Peptidase_S15 PF02129.18 CDJ48478.1 - 2.1 7.8 10.5 2.8 7.5 10.5 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Presenilin PF01080.17 CDJ48478.1 - 5.2 5.7 11.2 5.1 5.8 11.2 1.2 1 0 0 1 1 1 0 Presenilin Activator_LAG-3 PF11498.8 CDJ48478.1 - 6.1 5.7 32.7 7.2 5.5 32.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ureide_permease PF07168.11 CDJ48479.1 - 0.011 14.6 0.4 0.012 14.3 0.4 1.0 1 0 0 1 1 1 0 Ureide permease FTZ PF03867.14 CDJ48479.1 - 0.031 13.8 2.4 0.034 13.7 2.4 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region TFIIA PF03153.13 CDJ48479.1 - 0.043 13.8 9.7 0.046 13.7 9.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ48479.1 - 0.052 12.2 13.2 0.056 12.1 13.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pro_racemase PF05544.11 CDJ48479.1 - 0.061 12.4 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Proline racemase TERB2 PF15101.6 CDJ48479.1 - 0.063 13.3 5.4 0.083 12.9 5.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4834 PF16118.5 CDJ48479.1 - 0.068 14.1 2.0 0.091 13.7 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Syntaxin-18_N PF10496.9 CDJ48479.1 - 0.14 12.4 1.9 3.6 7.9 1.1 2.4 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Caudo_TAP PF02413.17 CDJ48479.1 - 0.14 12.3 6.7 0.22 11.7 6.7 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Usp PF00582.26 CDJ48479.1 - 0.16 12.4 0.1 0.21 12.1 0.1 1.1 1 0 0 1 1 1 0 Universal stress protein family Spt20 PF12090.8 CDJ48479.1 - 1.5 8.4 18.1 1.9 8.1 18.1 1.1 1 0 0 1 1 1 0 Spt20 family dsDNA_bind PF01984.20 CDJ48479.1 - 1.9 8.8 16.6 3.8 7.8 16.6 1.5 1 1 0 1 1 1 0 Double-stranded DNA-binding domain Activator_LAG-3 PF11498.8 CDJ48481.1 - 0.39 9.6 23.8 0.73 8.7 23.8 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ48481.1 - 0.76 9.7 33.4 0.48 10.4 27.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UPF0492 PF15744.5 CDJ48481.1 - 5.7 6.0 10.0 8.5 5.5 10.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 DUF1387 PF07139.11 CDJ48481.1 - 8.2 6.1 8.4 0.71 9.6 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Thiolase_N PF00108.23 CDJ48487.1 - 4.4e-45 154.1 0.0 7.1e-21 74.7 0.0 3.0 2 1 1 3 3 3 3 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 CDJ48487.1 - 8e-05 22.3 7.7 0.0087 15.7 4.2 3.2 2 1 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CDJ48487.1 - 0.00033 20.4 0.4 0.07 13.0 0.0 2.7 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Trp_oprn_chp PF09534.10 CDJ48489.1 - 0.0057 16.5 20.0 0.0067 16.2 20.0 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DcuA_DcuB PF03605.14 CDJ48489.1 - 0.028 13.3 8.6 0.036 13.0 8.6 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter TraT PF05818.12 CDJ48489.1 - 0.03 14.0 12.7 0.038 13.7 12.7 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein TFIIA PF03153.13 CDJ48489.1 - 0.038 14.0 18.4 0.043 13.8 18.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ48489.1 - 0.058 14.4 1.9 0.08 13.9 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ECM1 PF05782.11 CDJ48489.1 - 0.11 11.4 10.2 0.13 11.2 10.2 1.0 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) UPF0560 PF10577.9 CDJ48489.1 - 0.14 10.7 5.2 0.14 10.7 5.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Suf PF05843.14 CDJ48489.1 - 0.21 11.5 4.3 0.2 11.6 4.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ48489.1 - 0.27 10.8 18.8 0.34 10.5 18.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ48489.1 - 0.32 9.9 13.7 0.43 9.5 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Roughex PF06020.11 CDJ48489.1 - 0.34 10.0 3.7 0.34 10.0 3.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF2298 PF10060.9 CDJ48489.1 - 0.37 9.4 6.9 0.39 9.4 6.9 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) FAM199X PF15814.5 CDJ48489.1 - 0.66 9.0 8.4 0.82 8.7 8.4 1.1 1 0 0 1 1 1 0 Protein family FAM199X R_equi_Vir PF05526.11 CDJ48489.1 - 1.2 8.9 10.2 1.6 8.5 10.2 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Peptidase_S15 PF02129.18 CDJ48489.1 - 1.7 8.1 9.0 2.1 7.9 9.0 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Band_7 PF01145.25 CDJ48489.1 - 4.9 7.1 17.4 7.7 6.5 17.4 1.3 1 0 0 1 1 1 0 SPFH domain / Band 7 family Tic110 PF16940.5 CDJ48489.1 - 9.3 4.6 15.4 10 4.4 15.4 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter RNA_pol_L PF01193.24 CDJ48492.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain eIF-6 PF01912.18 CDJ48493.1 - 1.8e-74 249.4 0.0 3e-74 248.7 0.0 1.2 1 0 0 1 1 1 1 eIF-6 family DUF2207 PF09972.9 CDJ48494.1 - 0.27 10.0 0.6 0.36 9.5 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4366 PF14283.6 CDJ48494.1 - 5.4 7.1 8.2 0.59 10.2 1.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Med3 PF11593.8 CDJ48495.1 - 1e-05 25.0 7.4 1e-05 25.0 7.4 7.7 6 2 0 6 6 6 1 Mediator complex subunit 3 fungal SprA-related PF12118.8 CDJ48495.1 - 0.00071 18.8 8.6 0.00071 18.8 8.6 5.8 5 1 1 6 6 6 2 SprA-related family Suf PF05843.14 CDJ48495.1 - 0.027 14.4 0.3 0.027 14.4 0.3 4.5 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) Lin-8 PF03353.15 CDJ48496.1 - 0.012 15.2 5.7 0.012 15.2 5.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4667 PF15700.5 CDJ48496.1 - 0.012 15.8 8.2 0.017 15.2 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ48496.1 - 0.033 13.8 11.2 0.044 13.4 11.2 1.2 1 0 0 1 1 1 0 Spt20 family DUF3446 PF11928.8 CDJ48496.1 - 0.037 14.3 7.2 0.037 14.3 7.2 2.2 2 1 0 2 2 2 0 Early growth response N-terminal domain Apt1 PF10351.9 CDJ48496.1 - 0.089 11.6 8.3 0.096 11.5 8.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Roughex PF06020.11 CDJ48496.1 - 0.097 11.8 5.6 0.12 11.5 5.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein RR_TM4-6 PF06459.12 CDJ48496.1 - 0.1 12.4 5.8 0.13 12.1 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 CDJ48496.1 - 0.11 12.5 11.6 0.13 12.3 11.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 CDJ48496.1 - 0.16 12.1 3.4 0.2 11.8 3.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF1635 PF07795.11 CDJ48496.1 - 0.18 11.7 9.3 0.3 10.9 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) FHIPEP PF00771.20 CDJ48496.1 - 0.2 10.1 0.6 0.23 9.9 0.6 1.1 1 0 0 1 1 1 0 FHIPEP family Smg8_Smg9 PF10220.9 CDJ48496.1 - 0.2 9.9 4.9 0.24 9.7 4.9 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Plasmodium_Vir PF05795.11 CDJ48496.1 - 0.26 10.7 5.5 0.27 10.6 5.5 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GREB1 PF15782.5 CDJ48496.1 - 0.38 7.8 8.2 0.41 7.7 8.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NPR1_interact PF15699.5 CDJ48496.1 - 0.39 11.4 8.1 0.14 12.8 4.4 1.8 2 0 0 2 2 2 0 NPR1 interacting Maf1 PF09174.10 CDJ48496.1 - 0.44 10.7 4.9 0.68 10.1 4.9 1.2 1 0 0 1 1 1 0 Maf1 regulator Coilin_N PF15862.5 CDJ48496.1 - 0.44 10.4 9.4 0.16 11.7 3.9 2.1 2 0 0 2 2 2 0 Coilin N-terminus FAM60A PF15396.6 CDJ48496.1 - 0.49 10.4 4.2 0.67 9.9 4.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Ndc1_Nup PF09531.10 CDJ48496.1 - 0.81 8.3 6.1 0.91 8.1 6.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_60s PF00428.19 CDJ48496.1 - 1 10.0 9.1 1.9 9.1 9.1 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sec62 PF03839.16 CDJ48496.1 - 1.5 8.3 5.2 2.1 7.8 5.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Sox_N PF12444.8 CDJ48496.1 - 8.4 7.6 15.9 14 6.9 3.2 2.3 2 0 0 2 2 2 0 Sox developmental protein N terminal RskA PF10099.9 CDJ48497.1 - 6.2e-05 23.4 16.8 0.0051 17.1 4.8 2.3 2 0 0 2 2 2 2 Anti-sigma-K factor rskA CCDC24 PF15669.5 CDJ48497.1 - 0.00019 21.4 3.6 0.00019 21.4 3.6 2.2 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 24 family ICAP-1_inte_bdg PF10480.9 CDJ48497.1 - 0.011 15.7 4.2 0.011 15.7 4.2 2.2 2 0 0 2 2 2 0 Beta-1 integrin binding protein CpXC PF14353.6 CDJ48497.1 - 0.064 13.3 0.7 0.17 11.9 0.7 1.6 1 0 0 1 1 1 0 CpXC protein DUF3446 PF11928.8 CDJ48497.1 - 0.97 9.8 25.2 0.051 13.9 7.3 3.4 4 0 0 4 4 4 0 Early growth response N-terminal domain Filament_head PF04732.14 CDJ48497.1 - 3.3 8.7 24.2 2.8 8.9 12.7 2.6 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region DUF508 PF04370.12 CDJ48497.1 - 4 7.2 18.3 6.9 6.4 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Abhydrolase_9_N PF15420.6 CDJ48497.1 - 4.1 7.3 12.2 0.66 9.9 2.5 2.8 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus Ribosomal_60s PF00428.19 CDJ48497.1 - 4.2 8.0 31.9 0.49 11.0 9.8 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Dehydrin PF00257.19 CDJ48499.1 - 0.022 15.3 8.4 0.022 15.3 8.4 3.0 3 0 0 3 3 3 0 Dehydrin Roughex PF06020.11 CDJ48499.1 - 0.24 10.5 3.8 0.38 9.8 3.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ48499.1 - 0.62 10.0 15.2 0.061 13.3 10.6 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CDJ48499.1 - 7.4 3.5 6.8 9.9 3.1 6.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pox_A11 PF05061.13 CDJ48502.1 - 0.059 12.6 0.3 1.2 8.4 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A11 Protein DUF4667 PF15700.5 CDJ48502.1 - 0.46 10.5 23.6 0.19 11.8 6.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) DUF4614 PF15391.6 CDJ48502.1 - 1.4 8.9 20.6 0.17 11.9 5.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) DUF677 PF05055.12 CDJ48503.1 - 0.21 10.5 2.9 0.36 9.7 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF677) PPP4R2 PF09184.11 CDJ48503.1 - 0.78 9.3 12.0 1 8.9 12.0 1.1 1 0 0 1 1 1 0 PPP4R2 RAB3GAP2_N PF14655.6 CDJ48503.1 - 3 7.0 15.9 0.054 12.8 2.7 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PEHE PF15275.6 CDJ48503.1 - 5.7 7.6 12.2 1.8 9.2 7.6 2.1 2 0 0 2 2 2 0 PEHE domain WD40 PF00400.32 CDJ48504.1 - 0.00061 20.5 2.7 0.03 15.2 0.9 2.7 2 1 0 2 2 2 1 WD domain, G-beta repeat Hira PF07569.11 CDJ48504.1 - 0.03 14.1 0.1 0.056 13.2 0.0 1.4 1 1 0 1 1 1 0 TUP1-like enhancer of split SR-25 PF10500.9 CDJ48504.1 - 0.086 12.4 5.6 0.11 12.2 5.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LCD1 PF09798.9 CDJ48505.1 - 1.1 7.7 5.1 1.3 7.4 5.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4834 PF16118.5 CDJ48505.1 - 3.4 8.7 9.7 5.2 8.1 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4813 PF16072.5 CDJ48505.1 - 4.5 6.9 13.9 4.9 6.7 13.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF3391 PF11871.8 CDJ48506.1 - 0.11 13.1 13.0 0.12 12.9 13.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF501 PF04417.12 CDJ48506.1 - 0.19 11.5 8.4 0.24 11.2 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) EIIBC-GUT_N PF03612.14 CDJ48506.1 - 0.43 10.3 10.5 0.48 10.1 10.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ureide_permease PF07168.11 CDJ48506.1 - 0.44 9.2 3.5 0.43 9.3 3.5 1.1 1 0 0 1 1 1 0 Ureide permease SLC12 PF03522.15 CDJ48506.1 - 0.58 9.1 12.1 0.59 9.1 12.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4834 PF16118.5 CDJ48506.1 - 0.79 10.7 11.4 1.1 10.3 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MRP-S27 PF10037.9 CDJ48506.1 - 0.81 8.5 18.2 0.91 8.3 18.2 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Peptidase_U57 PF05582.12 CDJ48506.1 - 0.83 8.8 8.7 0.84 8.8 8.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Presenilin PF01080.17 CDJ48506.1 - 0.99 8.1 11.1 0.92 8.2 11.1 1.0 1 0 0 1 1 1 0 Presenilin Coilin_N PF15862.5 CDJ48506.1 - 1.1 9.1 13.4 1.2 8.9 13.4 1.1 1 0 0 1 1 1 0 Coilin N-terminus Serinc PF03348.15 CDJ48506.1 - 1.2 7.9 8.6 1.2 8.0 8.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) CobT PF06213.12 CDJ48506.1 - 1.2 8.4 17.2 1.2 8.4 17.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDHD PF02862.17 CDJ48506.1 - 1.4 9.0 11.5 1.4 9.0 11.5 1.0 1 0 0 1 1 1 0 DDHD domain EOS1 PF12326.8 CDJ48506.1 - 2.3 8.1 4.8 2.1 8.2 4.8 1.1 1 0 0 1 1 1 0 N-glycosylation protein AIF_C PF14721.6 CDJ48506.1 - 2.4 8.5 8.6 2.6 8.4 8.6 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Connexin PF00029.19 CDJ48506.1 - 2.7 7.7 7.5 2.5 7.8 7.5 1.1 1 0 0 1 1 1 0 Connexin Met_synt_B12 PF02965.17 CDJ48506.1 - 3.2 7.1 12.3 3.7 6.9 12.3 1.2 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain TFIIA PF03153.13 CDJ48506.1 - 3.4 7.6 31.3 3.3 7.6 31.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLN3 PF02487.17 CDJ48506.1 - 3.7 6.5 7.6 3.6 6.6 7.6 1.0 1 0 0 1 1 1 0 CLN3 protein Ctr PF04145.15 CDJ48506.1 - 3.8 8.1 7.2 4 8.0 7.2 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Neur_chan_memb PF02932.16 CDJ48506.1 - 4.5 7.3 6.9 4.2 7.4 6.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asn_synthase PF00733.21 CDJ48508.1 - 1.5e-59 202.5 0.0 2e-37 129.7 0.0 2.7 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CDJ48508.1 - 2.5e-36 124.3 0.0 4.1e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CDJ48508.1 - 2.1e-27 95.9 0.0 3.8e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CDJ48508.1 - 2.7e-09 36.8 0.0 7.1e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Aluminium induced protein DUF1933 PF09147.10 CDJ48508.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) Macoilin PF09726.9 CDJ48508.1 - 0.16 10.5 2.7 0.22 10.0 2.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF515 PF04415.12 CDJ48508.1 - 0.87 7.9 11.1 1.3 7.3 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.9 CDJ48509.1 - 0.0052 16.4 19.7 0.0052 16.4 19.7 4.1 1 1 3 4 4 4 2 Nuclear RNA-splicing-associated protein Torus PF16131.5 CDJ48510.1 - 3.5e-28 98.5 0.7 3.5e-28 98.5 0.7 4.0 5 0 0 5 5 5 1 Torus domain RRM_1 PF00076.22 CDJ48510.1 - 0.00028 20.6 0.0 0.00071 19.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 CDJ48510.1 - 0.074 12.9 7.9 0.14 12.0 7.9 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDJ48510.1 - 0.6 10.2 8.5 1.6 8.9 8.5 1.8 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 CDJ48510.1 - 4.1 8.0 5.7 9.8 6.8 5.7 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PNK3P PF08645.11 CDJ48511.1 - 0.0061 16.3 0.1 0.014 15.1 0.1 1.8 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase DUF2608 PF11019.8 CDJ48511.1 - 0.091 12.2 0.7 0.17 11.3 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2608) RabGGT_insert PF07711.11 CDJ48511.1 - 0.1 13.1 1.2 0.21 12.1 0.1 1.9 2 0 0 2 2 2 0 Rab geranylgeranyl transferase alpha-subunit, insert domain HAD_2 PF13419.6 CDJ48511.1 - 0.92 9.6 3.1 1.3 9.1 0.9 2.4 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DHHC PF01529.20 CDJ48512.1 - 5.8e-19 68.5 3.5 7.2e-19 68.2 3.5 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF5453 PF17534.2 CDJ48512.1 - 0.0055 16.7 0.1 0.0071 16.3 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5453) 60KD_IMP PF02096.20 CDJ48513.1 - 0.0003 20.7 0.0 0.00062 19.7 0.0 1.5 2 0 0 2 2 2 1 60Kd inner membrane protein Pex14_N PF04695.13 CDJ48514.1 - 2.6 8.7 18.3 3.4 8.3 18.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 CDJ48515.1 - 0.021 13.6 20.3 0.021 13.5 20.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LptF_LptG PF03739.14 CDJ48515.1 - 0.12 11.1 2.7 0.17 10.7 2.7 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG AF-4 PF05110.13 CDJ48515.1 - 0.52 8.3 29.0 0.63 8.1 29.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PNISR PF15996.5 CDJ48515.1 - 0.53 10.5 30.4 0.85 9.9 30.4 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SOBP PF15279.6 CDJ48515.1 - 1.6 9.2 25.1 1.9 9.0 25.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Sporozoite_P67 PF05642.11 CDJ48515.1 - 2.6 6.0 27.4 3 5.8 27.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop53 PF07767.11 CDJ48515.1 - 4.1 6.7 30.5 5.9 6.2 30.5 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Atg14 PF10186.9 CDJ48515.1 - 4.7 6.2 29.5 5.2 6.1 29.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lin-8 PF03353.15 CDJ48515.1 - 6.3 6.3 29.7 9.7 5.6 29.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 CDJ48515.1 - 6.9 5.6 28.4 8.4 5.3 28.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Apt1 PF10351.9 CDJ48515.1 - 8.1 5.2 20.0 9.1 5.0 20.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ALMT PF11744.8 CDJ48515.1 - 8.3 5.1 17.7 12 4.5 17.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_S64 PF08192.11 CDJ48515.1 - 8.6 4.7 23.9 10 4.5 23.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 Miga PF10265.9 CDJ48515.1 - 9.1 5.1 15.6 12 4.8 15.6 1.3 1 0 0 1 1 1 0 Mitoguardin PAT1 PF09770.9 CDJ48516.1 - 0.21 9.8 49.7 0.24 9.6 49.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.7 CDJ48516.1 - 3.1 5.8 38.4 3.6 5.6 38.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LAP1C PF05609.12 CDJ48517.1 - 7.2 5.6 39.2 10 5.0 39.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 CDJ48518.1 - 0.00079 17.9 1.7 0.00092 17.6 1.7 1.2 1 0 0 1 1 1 1 CDC45-like protein EPL1 PF10513.9 CDJ48518.1 - 0.021 15.2 1.7 0.028 14.8 1.7 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like CYSTM PF12734.7 CDJ48518.1 - 0.036 14.4 4.4 0.04 14.2 2.5 2.2 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Raftlin PF15250.6 CDJ48518.1 - 0.045 12.5 2.7 0.055 12.2 2.7 1.1 1 0 0 1 1 1 0 Raftlin Nop14 PF04147.12 CDJ48518.1 - 0.045 12.0 4.6 0.056 11.7 4.6 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 CDJ48518.1 - 0.054 12.3 3.7 0.075 11.8 3.7 1.3 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ48518.1 - 0.26 11.1 4.9 0.36 10.6 4.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CDJ48518.1 - 0.32 8.0 4.5 0.4 7.8 4.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Roughex PF06020.11 CDJ48518.1 - 0.49 9.4 9.2 0.67 9.0 9.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF4637 PF15470.6 CDJ48518.1 - 0.66 9.7 8.7 1.6 8.4 8.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RNA_polI_A34 PF08208.11 CDJ48518.1 - 0.75 9.8 6.7 1.1 9.2 6.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GET2 PF08690.10 CDJ48518.1 - 2.6 7.6 7.4 4 7.0 7.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 TRAP_alpha PF03896.16 CDJ48518.1 - 3 7.0 9.9 2.6 7.2 7.8 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Hid1 PF12722.7 CDJ48518.1 - 3.5 5.6 5.2 4.4 5.3 5.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apt1 PF10351.9 CDJ48518.1 - 3.6 6.3 9.7 4.9 5.9 9.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AIF_C PF14721.6 CDJ48518.1 - 6.8 7.0 6.5 14 6.1 6.5 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Rrn6 PF10214.9 CDJ48518.1 - 9.5 4.6 10.6 13 4.1 10.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RCC1 PF00415.18 CDJ48519.1 - 1.1e-26 93.2 0.0 4.6e-10 40.0 0.0 5.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ48519.1 - 1.7e-15 56.3 8.7 5.5e-07 29.2 0.3 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat DDHD PF02862.17 CDJ48519.1 - 0.003 17.8 3.9 0.096 12.8 3.5 2.4 2 0 0 2 2 2 1 DDHD domain V_ATPase_I PF01496.19 CDJ48519.1 - 0.0055 14.7 10.1 0.0079 14.2 10.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family O-antigen_lig PF13425.6 CDJ48519.1 - 0.0058 15.5 0.5 0.0082 15.0 0.5 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Connexin PF00029.19 CDJ48519.1 - 0.0092 15.8 3.0 0.015 15.1 3.0 1.2 1 0 0 1 1 1 1 Connexin SARAF PF06682.12 CDJ48519.1 - 0.012 15.3 8.0 0.012 15.3 8.0 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF913 PF06025.12 CDJ48519.1 - 0.036 13.1 2.3 0.032 13.2 0.7 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Serinc PF03348.15 CDJ48519.1 - 0.037 13.0 2.1 0.062 12.2 2.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.16 CDJ48519.1 - 0.054 13.5 6.3 0.12 12.4 4.9 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TRAP_alpha PF03896.16 CDJ48519.1 - 0.13 11.4 2.3 0.2 10.9 2.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit OATP PF03137.20 CDJ48519.1 - 0.18 10.1 4.2 0.82 7.9 1.6 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PXA PF02194.15 CDJ48519.1 - 0.43 10.5 4.0 0.73 9.8 4.0 1.3 1 0 0 1 1 1 0 PXA domain PIP5K PF01504.18 CDJ48519.1 - 0.51 9.5 6.3 0.16 11.1 3.5 1.5 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Shisa PF13908.6 CDJ48519.1 - 0.54 10.5 17.3 0.14 12.3 10.7 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Zip PF02535.22 CDJ48519.1 - 0.84 8.8 6.3 0.047 12.9 0.5 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter SLC12 PF03522.15 CDJ48519.1 - 0.88 8.5 10.7 1.4 7.9 10.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 ORC5_C PF14630.6 CDJ48519.1 - 0.98 8.9 6.5 0.34 10.4 2.3 2.1 3 0 0 3 3 3 0 Origin recognition complex (ORC) subunit 5 C-terminus PAT1 PF09770.9 CDJ48519.1 - 1 7.5 22.6 1.5 7.0 22.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CLN3 PF02487.17 CDJ48519.1 - 1.1 8.2 4.9 2.2 7.3 4.9 1.4 1 0 0 1 1 1 0 CLN3 protein Dpy19 PF10034.9 CDJ48519.1 - 1.2 7.2 3.4 1.8 6.6 3.4 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Ctr PF04145.15 CDJ48519.1 - 1.3 9.6 5.3 16 6.1 2.8 2.5 2 0 0 2 2 2 0 Ctr copper transporter family SR-25 PF10500.9 CDJ48519.1 - 4.6 6.8 36.9 1.9 8.0 25.6 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BORG_CEP PF14957.6 CDJ48519.1 - 5.2 8.2 12.8 1.9 9.7 4.3 2.5 2 0 0 2 2 2 0 Cdc42 effector ALMT PF11744.8 CDJ48519.1 - 5.4 5.7 6.9 8.9 5.0 6.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DAG_kinase_N PF14513.6 CDJ48519.1 - 5.4 7.2 18.0 2.4 8.3 13.9 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Apt1 PF10351.9 CDJ48519.1 - 5.8 5.7 13.2 2.8 6.7 1.2 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Gti1_Pac2 PF09729.9 CDJ48519.1 - 7.7 6.6 12.0 93 3.0 11.3 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family TFIIA PF03153.13 CDJ48519.1 - 8.4 6.3 42.0 1.4 8.8 37.2 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1168 PF06658.12 CDJ48520.1 - 2.9e-17 62.8 26.0 2e-16 60.1 26.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) SRP-alpha_N PF04086.13 CDJ48520.1 - 0.64 9.9 23.4 0.96 9.3 23.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GCD14 PF08704.10 CDJ48520.1 - 1.1 8.9 3.5 1.7 8.3 3.5 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Utp14 PF04615.13 CDJ48520.1 - 1.4 7.4 27.1 1.7 7.2 27.1 1.0 1 0 0 1 1 1 0 Utp14 protein Asp-B-Hydro_N PF05279.11 CDJ48520.1 - 1.5 8.8 11.3 2.7 8.0 11.3 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MCU PF04678.13 CDJ48520.1 - 2.1 8.4 5.3 4.1 7.5 5.3 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter SOG2 PF10428.9 CDJ48520.1 - 4.6 6.3 21.9 5.8 6.0 21.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_S49_N PF08496.10 CDJ48520.1 - 6.1 6.9 16.1 12 6.0 16.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GREB1 PF15782.5 CDJ48520.1 - 6.6 3.7 17.7 8.2 3.4 17.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Connexin PF00029.19 CDJ48520.1 - 8 6.1 5.4 10 5.8 5.4 1.3 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ48522.1 - 0.0008 18.3 12.6 0.0008 18.3 12.6 2.0 2 0 0 2 2 2 2 Presenilin HEAT PF02985.22 CDJ48522.1 - 0.0024 18.0 0.1 0.3 11.5 0.1 2.9 2 0 0 2 2 2 1 HEAT repeat ALMT PF11744.8 CDJ48522.1 - 0.69 8.7 16.3 0.096 11.5 9.8 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter Lin-8 PF03353.15 CDJ48522.1 - 0.77 9.3 26.9 0.22 11.1 17.6 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Hamartin PF04388.12 CDJ48522.1 - 1.1 7.9 20.6 1.5 7.4 20.6 1.2 1 0 0 1 1 1 0 Hamartin protein SAPS PF04499.15 CDJ48522.1 - 1.2 7.9 12.9 1.8 7.2 12.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PNISR PF15996.5 CDJ48522.1 - 1.3 9.2 32.4 0.14 12.4 19.8 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR MAT1 PF06391.13 CDJ48522.1 - 4.4 7.1 31.6 6.7 6.5 2.3 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 LAP1C PF05609.12 CDJ48522.1 - 5.7 5.9 21.7 2.8 6.9 14.8 2.0 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) WTX PF09422.10 CDJ48522.1 - 7.2 5.6 17.9 0.98 8.4 10.9 2.0 2 0 0 2 2 2 0 WTX protein BAF1_ABF1 PF04684.13 CDJ48522.1 - 8.1 5.4 28.1 13 4.7 28.1 1.2 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FAM60A PF15396.6 CDJ48522.1 - 8.5 6.3 18.1 2.7 8.0 10.3 2.1 2 0 0 2 2 2 0 Protein Family FAM60A CDK5_activator PF03261.15 CDJ48523.1 - 0.52 9.8 28.0 1.1 8.7 28.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF2722 PF10846.8 CDJ48524.1 - 0.0015 17.5 17.5 0.0015 17.5 17.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Apt1 PF10351.9 CDJ48524.1 - 0.0067 15.3 3.1 0.0072 15.2 3.1 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Peptidase_S49_N PF08496.10 CDJ48524.1 - 0.0075 16.3 0.4 0.0075 16.3 0.4 1.5 2 0 0 2 2 2 1 Peptidase family S49 N-terminal DUF4064 PF13273.6 CDJ48524.1 - 0.12 12.6 1.2 11 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) CSG2 PF16965.5 CDJ48524.1 - 0.14 11.1 1.7 0.15 11.0 1.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator MPM1 PF17234.2 CDJ48524.1 - 0.25 11.6 9.6 0.048 13.9 6.0 1.5 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 GREB1 PF15782.5 CDJ48524.1 - 0.26 8.3 8.2 0.27 8.3 8.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PigN PF04987.14 CDJ48524.1 - 0.51 9.1 3.8 0.28 10.0 1.6 1.6 2 0 0 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) CagX PF03524.15 CDJ48524.1 - 0.62 9.8 7.2 1.5 8.5 2.1 2.1 2 0 0 2 2 2 0 Conjugal transfer protein Lin-8 PF03353.15 CDJ48524.1 - 0.71 9.4 15.1 0.047 13.2 10.1 1.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Peroxin-13_N PF04088.13 CDJ48524.1 - 0.94 9.7 7.7 0.19 12.0 2.6 2.2 1 1 1 2 2 2 0 Peroxin 13, N-terminal region DUF4407 PF14362.6 CDJ48524.1 - 2.7 7.3 16.7 0.68 9.2 4.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Med15 PF09606.10 CDJ48524.1 - 3.6 6.2 30.3 0.025 13.3 17.1 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4199 PF13858.6 CDJ48524.1 - 5.8 7.3 6.0 5.5 7.4 3.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) PepSY_TM PF03929.16 CDJ48524.1 - 8 6.0 8.5 4.1 7.0 1.1 2.1 2 0 0 2 2 2 0 PepSY-associated TM region ORC5_C PF14630.6 CDJ48524.1 - 8.5 5.8 12.2 5.1 6.5 10.3 1.6 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Chromo PF00385.24 CDJ48525.1 - 7.9e-11 41.7 0.0 1.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_S4e PF00900.20 CDJ48526.1 - 4.6e-29 100.2 0.0 1e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 CDJ48526.1 - 3.7e-20 71.3 0.1 1.2e-19 69.7 0.0 1.8 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CDJ48526.1 - 8.7e-19 67.4 10.1 3.7e-18 65.3 9.4 2.2 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 CDJ48526.1 - 1.3e-06 28.0 0.0 2.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 CDJ48526.1 - 0.001 18.9 3.1 0.001 18.9 3.1 2.0 2 0 0 2 2 2 1 KOW motif SARAF PF06682.12 CDJ48527.1 - 0.0024 17.6 1.8 0.0029 17.3 1.8 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 CDJ48527.1 - 0.006 17.5 1.6 0.0093 16.9 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Serinc PF03348.15 CDJ48527.1 - 0.01 14.8 1.2 0.012 14.6 1.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Suf PF05843.14 CDJ48527.1 - 0.016 15.2 4.9 0.016 15.2 4.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ48527.1 - 0.019 15.0 17.9 0.021 14.8 17.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIP5K PF01504.18 CDJ48527.1 - 0.024 13.9 0.2 0.028 13.7 0.2 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase eIF-3_zeta PF05091.12 CDJ48527.1 - 0.028 13.4 5.1 0.029 13.4 5.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ctr PF04145.15 CDJ48527.1 - 0.037 14.7 2.3 0.044 14.4 2.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family GBP_C PF02841.14 CDJ48527.1 - 0.053 12.9 15.0 0.063 12.7 15.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RR_TM4-6 PF06459.12 CDJ48527.1 - 0.067 13.0 3.6 0.069 13.0 3.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RAB3GAP2_N PF14655.6 CDJ48527.1 - 0.072 12.3 6.3 0.084 12.1 6.3 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AIF_C PF14721.6 CDJ48527.1 - 0.074 13.4 3.1 0.1 12.9 3.1 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FHIPEP PF00771.20 CDJ48527.1 - 0.078 11.4 5.9 0.099 11.1 5.9 1.2 1 0 0 1 1 1 0 FHIPEP family Connexin PF00029.19 CDJ48527.1 - 0.08 12.7 0.7 0.092 12.5 0.7 1.1 1 0 0 1 1 1 0 Connexin EOS1 PF12326.8 CDJ48527.1 - 0.082 12.8 0.3 0.089 12.7 0.3 1.1 1 0 0 1 1 1 0 N-glycosylation protein Dehydrin PF00257.19 CDJ48527.1 - 0.088 13.4 5.3 0.12 12.9 5.3 1.2 1 0 0 1 1 1 0 Dehydrin LIM_bind PF01803.16 CDJ48527.1 - 0.15 11.5 5.0 0.19 11.2 5.0 1.1 1 0 0 1 1 1 0 LIM-domain binding protein SID-1_RNA_chan PF13965.6 CDJ48527.1 - 0.16 10.3 0.3 0.19 10.1 0.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDHD PF02862.17 CDJ48527.1 - 0.19 11.9 3.1 0.2 11.8 3.1 1.1 1 0 0 1 1 1 0 DDHD domain Calc_CGRP_IAPP PF00214.19 CDJ48527.1 - 0.21 12.0 4.1 0.3 11.5 4.1 1.2 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family EIIBC-GUT_N PF03612.14 CDJ48527.1 - 0.33 10.7 3.6 0.44 10.3 3.6 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Roughex PF06020.11 CDJ48527.1 - 0.41 9.7 9.6 0.47 9.5 9.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Spore_coat_CotO PF14153.6 CDJ48527.1 - 0.48 10.3 11.9 0.55 10.1 11.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FAM199X PF15814.5 CDJ48527.1 - 0.55 9.2 10.4 0.7 8.9 10.4 1.1 1 0 0 1 1 1 0 Protein family FAM199X THOC2_N PF16134.5 CDJ48527.1 - 0.57 8.7 5.7 0.64 8.6 5.7 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus PsaL PF02605.15 CDJ48527.1 - 1.3 8.6 5.9 0.59 9.8 3.2 1.7 1 1 1 2 2 2 0 Photosystem I reaction centre subunit XI Spt20 PF12090.8 CDJ48527.1 - 1.9 8.1 20.9 2.3 7.8 20.9 1.1 1 0 0 1 1 1 0 Spt20 family UPF0560 PF10577.9 CDJ48527.1 - 2.5 6.5 12.1 2.9 6.3 12.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hydin_ADK PF17213.3 CDJ48527.1 - 4.4 7.5 12.9 5.9 7.1 12.9 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Coilin_N PF15862.5 CDJ48527.1 - 6 6.7 11.5 8.2 6.2 11.5 1.1 1 0 0 1 1 1 0 Coilin N-terminus DUF1682 PF07946.14 CDJ48527.1 - 9.2 5.4 12.9 10 5.2 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Presenilin PF01080.17 CDJ48529.1 - 1.2 7.8 36.0 0.7 8.6 15.1 2.3 2 0 0 2 2 2 0 Presenilin PNISR PF15996.5 CDJ48529.1 - 5 7.3 29.7 5.8 7.1 13.2 2.4 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR T2SSM PF04612.12 CDJ48530.1 - 1.2 9.2 12.0 2.2 8.3 12.0 1.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Ribosomal_60s PF00428.19 CDJ48531.1 - 1.5e-05 25.5 46.1 0.053 14.1 6.1 4.4 4 0 0 4 4 4 4 60s Acidic ribosomal protein SUIM_assoc PF16619.5 CDJ48531.1 - 0.0002 21.4 14.4 0.072 13.2 1.1 2.9 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ48531.1 - 0.0012 18.5 2.1 0.0012 18.5 2.1 2.7 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein WD40 PF00400.32 CDJ48531.1 - 0.0023 18.7 4.4 0.038 14.9 0.0 3.5 3 1 0 3 3 3 1 WD domain, G-beta repeat RskA PF10099.9 CDJ48531.1 - 0.0027 18.0 1.3 0.0027 18.0 1.3 4.0 2 1 1 3 3 3 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ48531.1 - 0.0035 17.0 2.8 0.0035 17.0 2.8 2.1 2 0 0 2 2 2 1 Spt20 family TFIIA PF03153.13 CDJ48531.1 - 0.0058 16.7 4.5 0.0058 16.7 4.5 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ48531.1 - 7.9 7.1 20.7 0.063 13.9 3.6 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dynactin_p62 PF05502.13 CDJ48532.1 - 0.0034 16.2 13.1 0.0034 16.2 13.1 4.7 4 1 1 5 5 5 4 Dynactin p62 family Velvet PF11754.8 CDJ48532.1 - 0.025 14.5 0.2 0.025 14.5 0.2 2.2 2 1 0 2 2 2 0 Velvet factor B12D PF06522.11 CDJ48532.1 - 0.89 9.4 3.0 12 5.8 0.3 3.5 4 0 0 4 4 4 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Peptidase_C1 PF00112.23 CDJ48534.1 - 8.8e-14 52.1 0.9 9e-10 39.0 0.0 3.9 2 2 1 3 3 2 2 Papain family cysteine protease CathepsinC_exc PF08773.11 CDJ48534.1 - 3.3e-07 30.6 0.0 3.3e-07 30.6 0.0 3.5 2 1 0 2 2 1 1 Cathepsin C exclusion domain DUF4746 PF15928.5 CDJ48534.1 - 0.011 15.2 8.1 0.019 14.4 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SPX PF03105.19 CDJ48534.1 - 0.042 13.8 15.5 0.061 13.2 15.5 1.2 1 0 0 1 1 1 0 SPX domain Lin-8 PF03353.15 CDJ48534.1 - 1.1 8.8 26.9 1.8 8.0 26.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FAM60A PF15396.6 CDJ48534.1 - 2.6 8.0 16.9 9.3 6.2 14.6 2.2 2 0 0 2 2 2 0 Protein Family FAM60A V_ATPase_I PF01496.19 CDJ48534.1 - 2.7 5.8 17.1 4.8 5.0 17.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ48534.1 - 3 7.6 11.8 3.3 7.4 10.4 1.7 2 0 0 2 2 2 0 Connexin TT_ORF1 PF02956.14 CDJ48534.1 - 4 6.0 15.3 0.87 8.2 10.6 1.9 2 0 0 2 2 2 0 TT viral orf 1 Peptidase_S64 PF08192.11 CDJ48534.1 - 5.2 5.4 19.6 7.6 4.9 19.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 MDM10 PF12519.8 CDJ48534.1 - 5.6 5.7 13.3 8.8 5.1 13.3 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 GIDA_assoc PF13932.6 CDJ48534.1 - 5.8 7.0 14.0 1.5 8.9 10.9 1.5 2 0 0 2 2 2 0 GidA associated domain FAM176 PF14851.6 CDJ48534.1 - 6.6 6.4 11.7 3.6 7.3 8.6 1.9 2 0 0 2 2 2 0 FAM176 family Paramyxo_ncap PF00973.19 CDJ48534.1 - 6.9 5.5 11.6 11 4.8 11.6 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein LMBR1 PF04791.16 CDJ48534.1 - 9 5.1 7.7 14 4.5 7.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TFIIA PF03153.13 CDJ48535.1 - 2.3e-05 24.6 48.8 2.3e-05 24.6 48.8 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.8 CDJ48535.1 - 2.4e-05 23.7 34.2 2.4e-05 23.7 34.2 1.7 2 0 0 2 2 2 1 SprA-related family Exonuc_VII_L PF02601.15 CDJ48535.1 - 0.0029 17.2 17.9 0.0045 16.6 17.9 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit SID-1_RNA_chan PF13965.6 CDJ48535.1 - 0.037 12.5 6.5 0.044 12.2 6.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAPS PF04499.15 CDJ48535.1 - 0.045 12.5 12.8 0.057 12.2 12.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TCP PF03634.13 CDJ48535.1 - 0.085 13.4 22.0 0.021 15.4 18.4 1.9 2 0 0 2 2 2 0 TCP family transcription factor SAGA-Tad1 PF12767.7 CDJ48535.1 - 0.28 10.9 19.7 0.15 11.8 16.4 1.9 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit NPR3 PF03666.13 CDJ48535.1 - 0.31 9.8 24.5 0.49 9.1 24.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GREB1 PF15782.5 CDJ48535.1 - 0.33 8.0 22.6 0.45 7.6 22.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF-3_zeta PF05091.12 CDJ48535.1 - 0.39 9.6 29.7 0.76 8.7 29.7 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ48535.1 - 0.41 9.3 34.3 0.72 8.5 34.3 1.3 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ48535.1 - 0.58 9.9 30.7 1 9.1 30.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 CDJ48535.1 - 0.62 10.2 30.2 0.066 13.4 25.7 1.6 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Endostatin PF06482.11 CDJ48535.1 - 1.1 8.7 24.9 1.7 8.0 24.9 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Velvet PF11754.8 CDJ48535.1 - 1.8 8.4 25.0 0.98 9.3 22.7 1.7 2 0 0 2 2 2 0 Velvet factor VIR_N PF15912.5 CDJ48535.1 - 2.2 7.8 13.0 3.3 7.2 13.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Plasmodium_Vir PF05795.11 CDJ48535.1 - 3.4 7.0 12.2 0.39 10.1 8.1 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF913 PF06025.12 CDJ48535.1 - 8.8 5.2 17.8 18 4.2 17.8 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF755 PF05501.11 CDJ48536.1 - 0.00025 21.3 12.5 0.00025 21.3 12.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF755) DUF1635 PF07795.11 CDJ48536.1 - 0.0048 16.8 6.9 0.0053 16.7 6.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) SR-25 PF10500.9 CDJ48536.1 - 0.017 14.7 13.4 0.022 14.4 13.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CDJ48536.1 - 0.034 14.7 7.9 0.049 14.2 7.9 1.3 1 0 0 1 1 1 0 Dehydrin PGA2 PF07543.12 CDJ48536.1 - 0.041 13.9 1.5 0.05 13.6 1.5 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Spt20 PF12090.8 CDJ48536.1 - 0.049 13.2 7.3 0.052 13.2 7.3 1.1 1 0 0 1 1 1 0 Spt20 family DUF3381 PF11861.8 CDJ48536.1 - 0.14 11.9 7.3 0.17 11.7 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Androgen_recep PF02166.16 CDJ48536.1 - 0.16 10.8 5.4 0.17 10.7 5.4 1.2 1 0 0 1 1 1 0 Androgen receptor CCDC106 PF15794.5 CDJ48536.1 - 0.29 10.8 8.4 0.36 10.5 8.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Presenilin PF01080.17 CDJ48536.1 - 1.5 7.5 4.5 1.5 7.5 4.5 1.0 1 0 0 1 1 1 0 Presenilin Dsh_C PF12316.8 CDJ48536.1 - 3.6 8.0 10.0 4.5 7.6 10.0 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TFIIA PF03153.13 CDJ48537.1 - 0.03 14.3 23.0 0.034 14.2 23.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ48537.1 - 0.034 14.4 0.4 0.034 14.4 0.4 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Mem_trans PF03547.18 CDJ48537.1 - 3.4 6.0 7.9 3.7 5.8 7.9 1.3 1 0 0 1 1 1 0 Membrane transport protein CytochromB561_N PF09786.9 CDJ48537.1 - 7.2 5.5 17.6 8.6 5.2 17.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Trp_oprn_chp PF09534.10 CDJ48539.1 - 0.00031 20.6 39.8 0.1 12.4 2.7 3.3 3 0 0 3 3 3 3 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Nuc_sug_transp PF04142.15 CDJ48540.1 - 6.5e-12 45.2 0.0 6.5e-12 45.2 0.0 3.2 2 2 1 3 3 3 2 Nucleotide-sugar transporter Glyco_trans_4_3 PF12000.8 CDJ48540.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.5 2 1 0 2 2 2 0 Glycosyl transferase family 4 group DUF2339 PF10101.9 CDJ48540.1 - 0.41 9.2 47.3 0.51 8.9 47.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Androgen_recep PF02166.16 CDJ48541.1 - 0.077 11.8 6.8 0.11 11.3 6.2 1.5 2 0 0 2 2 2 0 Androgen receptor DUF4834 PF16118.5 CDJ48541.1 - 0.1 13.6 0.2 0.14 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SUIM_assoc PF16619.5 CDJ48541.1 - 0.15 12.1 10.7 0.29 11.2 10.7 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LCCL PF03815.19 CDJ48542.1 - 8e-18 64.3 0.0 1.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Laminin_G_3 PF13385.6 CDJ48542.1 - 0.00014 22.1 0.0 0.0002 21.5 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CxxCxxCC PF03692.15 CDJ48542.1 - 0.14 12.8 0.3 0.24 12.1 0.3 1.5 1 1 0 1 1 1 0 Putative zinc- or iron-chelating domain DUF2956 PF11169.8 CDJ48543.1 - 0.0036 17.5 3.6 0.0036 17.5 3.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2956) Peroxin-13_N PF04088.13 CDJ48543.1 - 0.007 16.7 8.5 0.072 13.4 0.2 2.0 2 0 0 2 2 2 1 Peroxin 13, N-terminal region Orf78 PF06024.12 CDJ48543.1 - 0.0081 16.4 8.5 0.33 11.3 0.6 2.1 2 0 0 2 2 2 2 Orf78 (ac78) Presenilin PF01080.17 CDJ48543.1 - 0.018 13.8 15.1 0.023 13.5 15.1 1.1 1 0 0 1 1 1 0 Presenilin Conotoxin PF02950.17 CDJ48543.1 - 0.019 16.0 16.6 0.065 14.3 4.5 2.5 2 1 1 3 3 2 0 Conotoxin DUF4484 PF14831.6 CDJ48543.1 - 0.022 14.8 7.1 0.8 9.7 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Eapp_C PF10238.9 CDJ48543.1 - 0.025 14.7 16.1 0.4 10.8 5.0 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein Erv26 PF04148.13 CDJ48543.1 - 0.027 14.3 0.2 0.035 13.9 0.2 1.2 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 PIP5K PF01504.18 CDJ48543.1 - 0.046 12.9 8.6 0.06 12.6 8.6 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase GRP PF07172.11 CDJ48543.1 - 0.06 14.0 4.5 2 9.2 0.5 2.2 2 0 0 2 2 2 0 Glycine rich protein family CSG2 PF16965.5 CDJ48543.1 - 0.067 12.1 4.8 0.085 11.8 4.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator SARAF PF06682.12 CDJ48543.1 - 0.079 12.6 8.6 0.12 12.0 8.6 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis 7tm_1 PF00001.21 CDJ48543.1 - 0.091 12.1 0.0 0.091 12.1 0.0 2.0 1 1 1 2 2 1 0 7 transmembrane receptor (rhodopsin family) DUF2828 PF11443.8 CDJ48543.1 - 0.097 10.7 11.8 0.13 10.3 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MAM33 PF02330.16 CDJ48543.1 - 0.1 12.6 15.8 0.38 10.7 1.3 2.0 2 0 0 2 2 2 0 Mitochondrial glycoprotein EIIBC-GUT_N PF03612.14 CDJ48543.1 - 0.14 11.9 14.4 0.37 10.5 0.9 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus CCDC53 PF10152.9 CDJ48543.1 - 0.19 12.2 14.3 0.85 10.0 1.8 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SLC12 PF03522.15 CDJ48543.1 - 0.19 10.7 12.7 0.23 10.4 12.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4050 PF13259.6 CDJ48543.1 - 0.27 11.6 10.1 0.36 11.2 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) RNA_pol_Rbc25 PF08292.12 CDJ48543.1 - 0.27 11.5 13.5 0.25 11.6 0.7 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 PRC2_HTH_1 PF18118.1 CDJ48543.1 - 0.31 11.9 12.0 1.3 9.8 0.7 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain DUF1248 PF06852.12 CDJ48543.1 - 0.33 10.4 2.7 0.16 11.4 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1248) EphA2_TM PF14575.6 CDJ48543.1 - 0.36 11.7 12.2 0.48 11.3 0.8 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4366 PF14283.6 CDJ48543.1 - 0.41 10.7 7.3 0.72 9.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) O-antigen_lig PF13425.6 CDJ48543.1 - 0.46 9.2 5.5 0.58 8.9 5.5 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Thg1C PF14413.6 CDJ48543.1 - 0.5 10.5 14.9 0.88 9.7 2.2 2.1 2 0 0 2 2 2 0 Thg1 C terminal domain TFB6 PF17110.5 CDJ48543.1 - 0.56 9.9 11.4 3.1 7.5 0.9 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH RAMP4 PF06624.12 CDJ48543.1 - 0.6 10.2 0.0 0.6 10.2 0.0 2.2 2 0 0 2 2 1 0 Ribosome associated membrane protein RAMP4 FYDLN_acid PF09538.10 CDJ48543.1 - 0.68 10.7 12.6 0.63 10.7 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) ALMT PF11744.8 CDJ48543.1 - 0.79 8.5 10.1 1.1 8.0 10.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Stig1 PF04885.13 CDJ48543.1 - 0.94 10.0 9.6 1.4 9.4 0.5 2.1 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 Otopetrin PF03189.13 CDJ48543.1 - 1 8.1 6.8 1.4 7.7 6.8 1.2 1 0 0 1 1 1 0 Otopetrin TRM13 PF05206.14 CDJ48543.1 - 1.1 8.8 11.5 1.7 8.1 1.3 2.0 2 0 0 2 2 2 0 Methyltransferase TRM13 Rrp15p PF07890.12 CDJ48543.1 - 1.1 9.6 19.6 0.28 11.5 1.8 2.1 2 0 0 2 2 2 0 Rrp15p PAXIP1_C PF15364.6 CDJ48543.1 - 1.2 9.4 19.1 2.3 8.5 6.7 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein OSTbeta PF15048.6 CDJ48543.1 - 1.8 8.7 8.8 7.1 6.8 2.4 2.1 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein ORC_WH_C PF18137.1 CDJ48543.1 - 1.9 8.6 18.0 0.89 9.6 1.6 2.0 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal CTU2 PF10288.9 CDJ48543.1 - 2 8.7 17.1 1.3 9.3 2.1 2.1 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF1840 PF08895.11 CDJ48543.1 - 2 8.8 17.4 0.8 10.1 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) WRNPLPNID PF15017.6 CDJ48543.1 - 2 9.3 20.0 1.7 9.6 6.2 2.1 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DUF3276 PF11680.8 CDJ48543.1 - 2.2 8.4 15.2 2.8 8.1 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) RskA PF10099.9 CDJ48543.1 - 2.2 8.5 10.4 13 6.0 10.6 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Tau95_N PF17682.1 CDJ48543.1 - 2.3 8.4 12.2 2.2 8.5 0.4 2.1 2 0 0 2 2 2 0 Tau95 Triple barrel domain Gaa1 PF04114.14 CDJ48543.1 - 2.3 7.1 11.1 0.16 11.0 0.9 2.0 1 1 1 2 2 2 0 Gaa1-like, GPI transamidase component RuvC_III PF18541.1 CDJ48543.1 - 2.5 8.0 13.5 2.4 8.0 1.4 2.1 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 HemX PF04375.14 CDJ48543.1 - 2.6 7.3 27.5 3.4 6.9 27.5 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CNDH2_N PF06278.11 CDJ48543.1 - 2.7 8.3 19.6 2.2 8.5 4.0 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal TMEM51 PF15345.6 CDJ48543.1 - 2.7 7.8 23.3 2.8 7.7 4.7 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 TMEM144 PF07857.12 CDJ48543.1 - 3 6.7 4.0 8.4 5.3 0.4 2.0 2 0 0 2 2 2 0 Transmembrane family, TMEM144 of transporters DUF3499 PF12005.8 CDJ48543.1 - 3.9 8.1 10.6 13 6.4 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) CbtA PF09490.10 CDJ48543.1 - 5 6.8 8.2 0.55 10.0 0.9 2.0 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) CAF1 PF04857.20 CDJ48543.1 - 5.1 6.2 12.3 6.7 5.8 12.3 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Anoctamin PF04547.12 CDJ48543.1 - 5.4 5.7 12.8 6.1 5.6 12.8 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel HA2 PF04408.23 CDJ48543.1 - 5.5 7.3 11.9 12 6.2 4.4 2.1 2 0 0 2 2 2 0 Helicase associated domain (HA2) DUF3464 PF11947.8 CDJ48543.1 - 5.7 6.7 18.8 3.3 7.5 6.3 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 CrgA PF06781.12 CDJ48543.1 - 5.9 7.0 8.7 3.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Cell division protein CrgA AIF_C PF14721.6 CDJ48543.1 - 6 7.2 15.5 4.7 7.6 4.0 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF5523 PF17661.1 CDJ48543.1 - 6.6 6.3 22.7 1.8 8.2 4.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5523) EPL1 PF10513.9 CDJ48543.1 - 7.3 6.9 21.9 5.1 7.5 7.0 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like DDRGK PF09756.9 CDJ48543.1 - 7.7 6.1 33.0 2.5 7.6 8.7 2.0 2 0 0 2 2 2 0 DDRGK domain Ferlin_C PF16165.5 CDJ48543.1 - 9.4 6.2 8.3 10 6.0 0.4 2.1 2 0 0 2 2 2 0 Ferlin C-terminus SRCR PF00530.18 CDJ48544.1 - 1.2e-20 73.9 5.7 1.1e-17 64.4 1.3 2.3 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain LCCL PF03815.19 CDJ48544.1 - 4.4e-15 55.6 1.7 1.1e-12 47.8 0.0 3.1 3 0 0 3 3 3 2 LCCL domain SRCR_2 PF15494.6 CDJ48544.1 - 9.2e-05 22.9 0.2 0.00018 22.0 0.2 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Ribosomal_L32e PF01655.18 CDJ48545.1 - 3.4e-47 159.3 0.5 4.3e-47 159.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 CDP-OH_P_transf PF01066.21 CDJ48546.1 - 5.9e-15 55.8 0.1 5.9e-15 55.8 0.1 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3007 PF11460.8 CDJ48546.1 - 0.045 14.0 1.2 0.045 14.0 1.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3007) EphA2_TM PF14575.6 CDJ48546.1 - 0.048 14.6 0.1 0.17 12.8 0.1 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PNP_UDP_1 PF01048.20 CDJ48547.1 - 5.1e-31 107.7 0.0 8e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Pkinase PF00069.25 CDJ48548.1 - 4e-40 137.8 0.0 1e-37 130.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ48548.1 - 6.4e-22 78.1 0.0 9.2e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ48548.1 - 1.3e-06 28.0 0.0 2.5e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDJ48548.1 - 8e-06 24.9 0.0 1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ48548.1 - 6.8e-05 22.9 0.1 0.00015 21.8 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ48548.1 - 0.24 10.9 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase MMR_HSR1 PF01926.23 CDJ48551.1 - 6.7e-15 55.2 0.0 9e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ48551.1 - 7.6e-06 25.9 0.0 0.019 14.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CDJ48551.1 - 0.00011 21.8 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ48551.1 - 0.0044 17.1 0.0 0.041 13.9 0.0 2.0 1 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 CDJ48551.1 - 0.008 15.7 0.0 2.6 7.5 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CDJ48551.1 - 0.15 12.6 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Notch PF00066.17 CDJ48554.1 - 9.3e-07 29.2 7.1 9.3e-07 29.2 7.1 3.9 3 0 0 3 3 3 1 LNR domain Big_5 PF13205.6 CDJ48554.1 - 5.9e-05 23.7 0.0 0.3 11.8 0.0 4.4 4 0 0 4 4 4 1 Bacterial Ig-like domain SIT PF15330.6 CDJ48554.1 - 0.0093 16.4 0.1 0.0093 16.4 0.1 9.4 9 1 2 11 11 11 1 SHP2-interacting transmembrane adaptor protein, SIT RskA PF10099.9 CDJ48554.1 - 0.014 15.7 0.0 0.014 15.7 0.0 26.7 13 8 6 21 21 21 0 Anti-sigma-K factor rskA Macoilin PF09726.9 CDJ48556.1 - 0.0013 17.4 20.9 0.0013 17.4 20.9 4.3 3 1 0 3 3 3 1 Macoilin family DUF1645 PF07816.11 CDJ48556.1 - 0.013 16.1 3.7 0.013 16.1 3.7 6.3 4 2 0 4 4 4 0 Protein of unknown function (DUF1645) RWD PF05773.22 CDJ48556.1 - 0.078 13.3 0.0 0.54 10.6 0.0 2.3 2 0 0 2 2 2 0 RWD domain Mit_KHE1 PF10173.9 CDJ48556.1 - 0.36 10.9 2.6 2.8 8.0 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related RskA PF10099.9 CDJ48557.1 - 0.0042 17.4 1.1 0.0042 17.4 1.1 2.6 1 1 2 3 3 3 1 Anti-sigma-K factor rskA Spore_coat_CotO PF14153.6 CDJ48557.1 - 2 8.3 22.9 1.4 8.8 7.0 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Roughex PF06020.11 CDJ48557.1 - 2 7.4 20.4 1.8 7.6 5.8 2.2 2 0 0 2 2 2 0 Drosophila roughex protein Big_2 PF02368.18 CDJ48557.1 - 3.5 7.6 13.6 0.15 12.0 1.6 2.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) SURF2 PF05477.11 CDJ48557.1 - 4.3 6.9 22.2 1.3 8.6 5.8 2.4 2 1 0 2 2 2 0 Surfeit locus protein 2 (SURF2) DivIC PF04977.15 CDJ48557.1 - 6.5 6.6 25.2 1.3 8.8 7.0 2.3 2 0 0 2 2 2 0 Septum formation initiator OmpH PF03938.14 CDJ48557.1 - 8.8 6.7 28.7 3 8.2 7.6 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF755 PF05501.11 CDJ48558.1 - 0.033 14.5 5.8 0.033 14.5 5.8 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF755) Tau95_N PF17682.1 CDJ48558.1 - 0.075 13.2 0.0 0.075 13.2 0.0 3.3 2 1 0 2 2 2 0 Tau95 Triple barrel domain Adeno_PV PF03910.13 CDJ48558.1 - 7.6 5.1 9.8 0.54 8.9 4.9 1.6 2 0 0 2 2 2 0 Adenovirus minor core protein PV RskA PF10099.9 CDJ48559.1 - 0.002 18.5 12.4 0.002 18.5 12.4 2.2 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Phage_TTP_11 PF16460.5 CDJ48559.1 - 0.13 12.1 0.1 5.9 6.7 0.0 2.3 1 1 1 2 2 2 0 Phage tail tube, TTP, lambda-like SR-25 PF10500.9 CDJ48560.1 - 0.0021 17.7 22.6 0.0025 17.5 9.2 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Connexin PF00029.19 CDJ48560.1 - 0.21 11.3 3.5 0.45 10.2 3.5 1.5 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 CDJ48560.1 - 0.25 9.7 0.2 0.33 9.3 0.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ48560.1 - 0.92 8.4 2.3 1.6 7.6 2.3 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF572 PF04502.13 CDJ48560.1 - 1.3 8.6 12.6 1.6 8.3 7.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.16 CDJ48560.1 - 1.9 8.5 19.4 1.1 9.2 13.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RICTOR_N PF14664.6 CDJ48560.1 - 3.3 6.6 5.2 5.7 5.8 5.2 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term V_ATPase_I PF01496.19 CDJ48560.1 - 4.4 5.1 9.3 7.6 4.3 9.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 CDJ48560.1 - 4.5 6.2 11.5 1.5 7.8 5.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SRP-alpha_N PF04086.13 CDJ48560.1 - 5.8 6.7 20.6 3.7 7.4 8.4 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal CSG2 PF16965.5 CDJ48560.1 - 6.2 5.7 5.4 11 4.9 5.4 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Zip PF02535.22 CDJ48560.1 - 9.8 5.3 13.3 1.5 7.9 5.8 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Rtf2 PF04641.12 CDJ48561.1 - 1.4 8.2 14.3 1.4 8.2 14.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger LIN37 PF15306.6 CDJ48561.1 - 2.4 8.4 22.3 2.6 8.2 22.3 1.0 1 0 0 1 1 1 0 LIN37 NPR3 PF03666.13 CDJ48561.1 - 5.2 5.7 16.2 6.5 5.4 16.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ChAPs PF09295.10 CDJ48561.1 - 8.7 5.2 9.0 0.9 8.5 4.5 1.5 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Pkinase PF00069.25 CDJ48565.1 - 1.5e-29 103.2 0.0 1.2e-27 97.0 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ48565.1 - 1.1e-09 38.0 0.0 1.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ48565.1 - 0.052 12.9 0.0 0.097 12.0 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 CDJ48565.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CDJ48565.1 - 0.19 11.6 0.0 8.5 6.2 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family IMCp PF12314.8 CDJ48566.1 - 4.7e-10 39.6 57.9 1.1e-07 32.0 35.9 3.3 1 1 2 3 3 3 3 Inner membrane complex protein SUIM_assoc PF16619.5 CDJ48566.1 - 0.048 13.7 0.0 0.048 13.7 0.0 3.4 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ48566.1 - 5.1 7.0 14.8 0.23 11.4 8.4 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4342 PF14242.6 CDJ48567.1 - 0.052 13.5 1.8 0.052 13.5 1.8 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4342) SRP-alpha_N PF04086.13 CDJ48567.1 - 1.3 8.9 4.8 3 7.7 4.8 1.5 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Apt1 PF10351.9 CDJ48568.1 - 0.00035 19.6 6.7 0.00035 19.6 6.7 1.9 2 0 0 2 2 2 1 Golgi-body localisation protein domain Sporozoite_P67 PF05642.11 CDJ48568.1 - 0.031 12.4 14.8 0.053 11.6 14.8 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen TFIIA PF03153.13 CDJ48568.1 - 0.45 10.4 25.3 0.7 9.8 25.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ48570.1 - 0.00022 20.9 30.8 0.0012 18.5 19.2 7.0 7 1 0 7 7 7 2 Spt20 family Shadoo PF14999.6 CDJ48570.1 - 0.0014 18.7 9.4 0.0014 18.7 9.4 19.0 11 2 8 19 19 19 1 Shadow of prion protein, neuroprotective STAC2_u1 PF16664.5 CDJ48570.1 - 0.0066 16.9 7.0 0.0066 16.9 7.0 6.5 7 0 0 7 7 7 1 Unstructured on SH3 and cysteine-rich domain-containing protein 2 RskA PF10099.9 CDJ48570.1 - 0.0086 16.4 11.1 0.0086 16.4 11.1 17.2 2 2 9 12 12 12 2 Anti-sigma-K factor rskA GREB1 PF15782.5 CDJ48573.1 - 0.11 9.6 0.9 0.15 9.1 0.6 1.4 1 1 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ATPase PF06745.13 CDJ48576.1 - 0.8 9.0 7.0 0.076 12.3 1.7 2.0 2 0 0 2 2 2 0 KaiC Ribosomal_S21 PF01165.20 CDJ48577.1 - 0.26 11.0 3.5 2.9 7.7 0.1 3.0 2 0 0 2 2 2 0 Ribosomal protein S21 Ras PF00071.22 CDJ48578.1 - 8.3e-33 113.3 0.0 1.3e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ48578.1 - 3.4e-25 88.6 0.1 7.8e-25 87.4 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ48578.1 - 8.6e-08 31.8 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ48578.1 - 7.9e-05 22.7 0.0 8.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dehydrin PF00257.19 CDJ48578.1 - 0.02 15.4 0.8 0.021 15.4 0.8 1.1 1 0 0 1 1 1 0 Dehydrin GTP_EFTU PF00009.27 CDJ48578.1 - 0.044 13.3 0.3 0.54 9.8 0.0 2.3 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain DAP3 PF10236.9 CDJ48578.1 - 0.057 12.6 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 CDJ48578.1 - 0.092 13.0 0.0 0.18 12.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CDJ48578.1 - 0.13 12.8 0.2 0.52 10.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 CDJ48578.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ribosomal_60s PF00428.19 CDJ48578.1 - 8.8 7.0 11.7 1 10.0 7.2 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein WD40 PF00400.32 CDJ48580.1 - 5.7e-11 42.8 17.0 0.00056 20.7 0.0 8.9 8 2 0 8 8 8 3 WD domain, G-beta repeat SUIM_assoc PF16619.5 CDJ48580.1 - 6.4e-06 26.1 5.5 0.0002 21.4 0.1 9.6 8 1 0 8 8 8 5 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ48580.1 - 1.8e-05 24.5 91.0 0.011 15.4 3.0 7.4 7 0 0 7 7 7 4 Spt20 family DUF2722 PF10846.8 CDJ48580.1 - 0.00022 20.3 64.1 0.022 13.7 1.3 6.7 7 0 0 7 7 7 5 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ48581.1 - 0.021 14.9 53.8 0.035 14.1 31.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CDJ48582.1 - 5.5e-50 170.2 1.2 4.7e-36 124.5 0.0 3.5 1 1 2 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ48582.1 - 6.6e-21 74.7 0.2 2e-17 63.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase PH PF00169.29 CDJ48582.1 - 8.3e-14 52.0 0.0 1.3e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.6 CDJ48582.1 - 3.5e-05 23.4 0.0 9.9e-05 22.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CDJ48582.1 - 7.7e-05 22.0 0.1 0.00014 21.1 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CDJ48582.1 - 8.5e-05 21.9 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 EF hand Pkinase_fungal PF17667.1 CDJ48582.1 - 0.00029 19.7 0.0 0.00029 19.7 0.0 2.6 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 CDJ48582.1 - 0.00059 19.2 0.0 0.00059 19.2 0.0 1.9 2 0 0 2 2 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_8 PF15409.6 CDJ48582.1 - 0.0063 16.8 0.1 0.018 15.3 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain Pox_ser-thr_kin PF05445.11 CDJ48582.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase EF-hand_8 PF13833.6 CDJ48582.1 - 0.017 15.0 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 CDJ48582.1 - 0.11 13.0 0.0 0.36 11.3 0.0 1.9 2 0 0 2 2 1 0 EF-hand domain pair PH_11 PF15413.6 CDJ48582.1 - 0.12 12.8 0.6 2.8 8.4 0.3 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain eIF-1a PF01176.19 CDJ48583.1 - 2.7e-11 43.1 0.0 7.8e-11 41.6 0.0 1.7 1 1 0 1 1 1 1 Translation initiation factor 1A / IF-1 FlgH PF02107.16 CDJ48583.1 - 0.021 14.5 0.7 0.032 13.9 0.7 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein PCNP PF15473.6 CDJ48583.1 - 0.1 13.3 5.3 3.1 8.5 0.2 2.1 2 0 0 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family RskA PF10099.9 CDJ48583.1 - 0.21 11.9 16.2 3.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA RSRP PF17069.5 CDJ48583.1 - 0.34 10.5 13.5 0.5 9.9 13.5 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 RXT2_N PF08595.11 CDJ48583.1 - 0.34 10.9 2.5 1.3 9.0 0.1 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal SR-25 PF10500.9 CDJ48583.1 - 0.39 10.3 21.8 0.072 12.7 18.4 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4692 PF15763.5 CDJ48583.1 - 0.57 10.6 5.7 0.15 12.6 1.3 1.9 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) AF-4 PF05110.13 CDJ48583.1 - 1.2 7.1 13.5 1.6 6.7 13.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FYDLN_acid PF09538.10 CDJ48583.1 - 1.2 9.8 10.1 0.94 10.2 7.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF3446 PF11928.8 CDJ48583.1 - 2.1 8.7 12.9 9.8 6.6 9.8 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain PBP1_TM PF14812.6 CDJ48583.1 - 3.4 8.1 11.3 6.4 7.2 8.5 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1635 PF07795.11 CDJ48583.1 - 3.7 7.3 4.9 5.3 6.8 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF3246 PF11596.8 CDJ48583.1 - 8.2 5.8 7.8 1.6 8.1 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) SR-25 PF10500.9 CDJ48584.1 - 0.0017 18.1 2.5 0.0017 18.1 2.5 4.5 3 2 0 4 4 4 1 Nuclear RNA-splicing-associated protein MAP7 PF05672.11 CDJ48584.1 - 0.0021 17.8 10.5 0.0021 17.8 10.5 3.5 3 0 0 3 3 3 2 MAP7 (E-MAP-115) family RskA PF10099.9 CDJ48584.1 - 0.014 15.7 8.6 0.014 15.7 8.6 7.2 2 2 3 5 5 5 0 Anti-sigma-K factor rskA Herpes_pp85 PF04637.12 CDJ48584.1 - 0.2 10.0 8.5 0.85 8.0 0.7 2.6 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SR-25 PF10500.9 CDJ48585.1 - 0.00085 19.0 16.8 0.0015 18.2 16.8 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Archease PF01951.16 CDJ48586.1 - 4.3e-18 65.9 18.3 3.6e-16 59.7 13.0 2.7 2 1 1 3 3 2 2 Archease protein family (MTH1598/TM1083) RAP1 PF07218.11 CDJ48586.1 - 0.0023 16.3 13.4 0.0023 16.3 13.4 2.0 1 1 1 2 2 2 1 Rhoptry-associated protein 1 (RAP-1) RskA PF10099.9 CDJ48586.1 - 0.0071 16.6 27.9 0.063 13.6 13.1 3.2 1 1 1 2 2 2 1 Anti-sigma-K factor rskA SPX PF03105.19 CDJ48586.1 - 0.42 10.5 33.5 0.045 13.7 20.4 2.2 2 0 0 2 2 2 0 SPX domain Presenilin PF01080.17 CDJ48586.1 - 0.59 8.8 28.7 0.23 10.2 9.2 2.2 2 0 0 2 2 2 0 Presenilin TMEM208_SND2 PF05620.11 CDJ48586.1 - 2.4 7.9 7.4 0.87 9.3 0.8 2.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Apt1 PF10351.9 CDJ48586.1 - 2.6 6.8 35.7 0.2 10.5 23.2 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain SLC12 PF03522.15 CDJ48586.1 - 3 6.8 23.1 1.7 7.6 1.7 2.1 2 0 0 2 2 2 0 Solute carrier family 12 BBS2_N PF14781.6 CDJ48586.1 - 3.4 7.6 7.5 13 5.8 0.4 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal DUF1387 PF07139.11 CDJ48586.1 - 4.2 7.0 29.0 0.67 9.6 9.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) PAT1 PF09770.9 CDJ48586.1 - 4.5 5.4 24.7 6 5.0 24.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peroxin-3 PF04882.12 CDJ48586.1 - 6.8 5.6 35.5 0.067 12.2 13.7 2.2 2 0 0 2 2 2 0 Peroxin-3 RNA_ligase PF09414.10 CDJ48586.1 - 7.6 6.8 7.5 17 5.6 7.5 1.6 1 1 0 1 1 1 0 RNA ligase Chorein_N PF12624.7 CDJ48586.1 - 9.3 6.4 13.5 12 6.1 5.6 2.3 2 0 0 2 2 2 0 N-terminal region of Chorein or VPS13 Tim54 PF11711.8 CDJ48588.1 - 0.0092 14.8 2.6 0.0081 15.0 2.6 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF2076 PF09849.9 CDJ48588.1 - 0.011 15.9 20.5 0.011 15.8 20.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SpoIIP PF07454.11 CDJ48588.1 - 0.015 14.8 4.2 0.015 14.7 4.2 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDJ48588.1 - 0.016 15.1 2.0 0.016 15.1 2.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spt20 PF12090.8 CDJ48588.1 - 0.028 14.0 29.0 0.034 13.8 29.0 1.1 1 0 0 1 1 1 0 Spt20 family CPSF100_C PF13299.6 CDJ48588.1 - 0.042 14.0 2.4 0.044 14.0 2.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4407 PF14362.6 CDJ48588.1 - 0.053 12.9 1.7 0.053 12.9 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 CDJ48588.1 - 0.098 10.6 2.0 0.09 10.7 2.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 CDJ48588.1 - 0.1 12.3 0.6 0.11 12.2 0.6 1.1 1 0 0 1 1 1 0 FAM176 family TFIIA PF03153.13 CDJ48588.1 - 0.1 12.6 25.5 0.11 12.4 25.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 CDJ48588.1 - 0.17 9.8 21.9 0.17 9.8 21.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Presenilin PF01080.17 CDJ48588.1 - 0.19 10.5 6.6 0.2 10.4 6.6 1.1 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 CDJ48588.1 - 0.23 9.9 11.8 0.23 9.9 11.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PAT1 PF09770.9 CDJ48588.1 - 0.29 9.4 15.6 0.33 9.2 15.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CobT PF06213.12 CDJ48588.1 - 0.33 10.3 12.4 0.39 10.1 12.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CLN3 PF02487.17 CDJ48588.1 - 0.42 9.6 1.6 0.42 9.6 1.6 1.1 1 0 0 1 1 1 0 CLN3 protein eIF-3_zeta PF05091.12 CDJ48588.1 - 0.45 9.4 9.6 0.51 9.3 9.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3408 PF11888.8 CDJ48588.1 - 0.46 10.6 10.2 0.6 10.2 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) OATP PF03137.20 CDJ48588.1 - 0.67 8.2 2.5 0.69 8.1 2.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Neur_chan_memb PF02932.16 CDJ48588.1 - 0.7 9.9 5.4 0.76 9.8 5.4 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CCDC53 PF10152.9 CDJ48588.1 - 0.79 10.1 13.0 0.92 9.9 13.0 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4770 PF15994.5 CDJ48588.1 - 1.2 9.3 12.5 1.4 9.1 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF1980 PF09323.10 CDJ48588.1 - 1.3 8.9 3.2 1.4 8.8 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Connexin PF00029.19 CDJ48588.1 - 1.3 8.7 3.9 1.6 8.5 3.9 1.1 1 0 0 1 1 1 0 Connexin eIF_4EBP PF05456.11 CDJ48588.1 - 1.6 8.7 14.3 2.8 7.9 14.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF2722 PF10846.8 CDJ48588.1 - 1.6 7.6 25.8 1.9 7.3 25.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) VIR_N PF15912.5 CDJ48588.1 - 1.8 8.1 9.4 2.1 7.9 9.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Ctr PF04145.15 CDJ48588.1 - 2 9.0 4.3 2.2 8.9 4.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Suf PF05843.14 CDJ48588.1 - 2.4 8.1 13.9 2.6 7.9 13.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 CDJ48588.1 - 2.4 8.2 14.5 2.8 7.9 14.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EIIBC-GUT_N PF03612.14 CDJ48588.1 - 3.3 7.4 7.4 4.2 7.1 7.4 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3464 PF11947.8 CDJ48588.1 - 3.4 7.4 11.1 4.4 7.1 11.1 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 GREB1 PF15782.5 CDJ48588.1 - 3.5 4.6 9.3 3.9 4.5 9.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BRF1 PF07741.13 CDJ48588.1 - 3.9 7.9 8.2 5 7.5 8.2 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Hid1 PF12722.7 CDJ48588.1 - 5.7 4.9 7.3 6.2 4.8 7.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PepSY_TM PF03929.16 CDJ48588.1 - 6.3 6.4 8.3 7.4 6.1 8.3 1.1 1 0 0 1 1 1 0 PepSY-associated TM region DUF4865 PF16157.5 CDJ48589.1 - 5.7 6.9 6.7 6.7 6.7 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) RskA PF10099.9 CDJ48590.1 - 5.9e-06 26.7 10.7 5.9e-06 26.7 10.7 2.1 2 0 0 2 2 1 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ48590.1 - 0.0066 16.1 16.9 0.0066 16.1 16.9 2.1 2 0 0 2 2 2 1 Spt20 family DUF2076 PF09849.9 CDJ48590.1 - 0.019 15.1 16.3 0.019 15.1 16.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) SR-25 PF10500.9 CDJ48590.1 - 0.058 13.0 36.1 0.11 12.1 35.7 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Stevor PF17410.2 CDJ48590.1 - 0.087 12.4 0.3 0.087 12.4 0.3 2.0 2 1 1 3 3 2 0 Subtelomeric Variable Open Reading frame Ndc1_Nup PF09531.10 CDJ48590.1 - 0.18 10.4 18.0 0.2 10.3 18.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDK2AP PF09806.9 CDJ48590.1 - 0.19 11.8 25.9 0.23 11.5 8.4 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein PEHE PF15275.6 CDJ48590.1 - 0.33 11.6 18.5 0.69 10.6 4.4 2.1 2 0 0 2 2 2 0 PEHE domain DUF2722 PF10846.8 CDJ48590.1 - 0.75 8.7 27.6 0.018 14.0 14.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ48590.1 - 1.2 7.7 26.9 1.3 7.6 26.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LAP1C PF05609.12 CDJ48590.1 - 1.3 8.0 21.5 1.5 7.8 21.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Herpes_pp85 PF04637.12 CDJ48590.1 - 1.3 7.3 5.3 1.7 6.9 5.3 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Peptidase_S64 PF08192.11 CDJ48590.1 - 5.8 5.3 18.3 6.8 5.0 18.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 RAP1 PF07218.11 CDJ48590.1 - 9.7 4.3 8.5 11 4.1 8.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RCC1 PF00415.18 CDJ48591.1 - 1.8e-38 130.9 15.2 2.4e-10 40.9 0.0 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ48591.1 - 3.7e-18 64.8 18.4 2.4e-07 30.4 0.2 4.5 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Phage_TAC_11 PF11836.8 CDJ48591.1 - 0.0033 17.5 5.6 0.0033 17.5 5.6 2.4 2 0 0 2 2 2 1 Phage tail tube protein, GTA-gp10 DUF2057 PF09829.9 CDJ48591.1 - 3.6 7.7 11.9 1.3 9.1 1.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) SR-25 PF10500.9 CDJ48591.1 - 8.8 5.9 26.3 2.2 7.8 6.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ48592.1 - 0.00037 20.8 15.6 0.0005 20.4 15.6 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SMC_N PF02463.19 CDJ48592.1 - 0.0094 15.4 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain TFIIA PF03153.13 CDJ48592.1 - 0.36 10.8 7.3 0.47 10.4 7.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4887 PF16228.5 CDJ48593.1 - 0.29 11.3 28.3 0.13 12.5 7.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4887) Med15 PF09606.10 CDJ48593.1 - 0.7 8.5 17.4 0.83 8.3 17.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ48593.1 - 2.6 8.0 18.9 3.9 7.4 18.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPT6_acidic PF14632.6 CDJ48594.1 - 9e-08 32.6 11.7 9e-08 32.6 11.7 10.9 8 2 2 10 10 10 1 Acidic N-terminal SPT6 IMUP PF15761.5 CDJ48594.1 - 0.00089 19.9 5.3 0.00089 19.9 5.3 14.8 7 2 7 14 14 14 2 Immortalisation up-regulated protein HHH_7 PF14635.6 CDJ48594.1 - 0.001 19.4 0.7 0.012 16.0 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix motif AAA_33 PF13671.6 CDJ48595.1 - 0.00018 21.6 0.1 0.00018 21.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ48595.1 - 0.00042 20.8 1.7 0.00042 20.8 1.7 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 CDJ48595.1 - 0.005 17.4 0.2 0.017 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 CDJ48595.1 - 0.063 12.7 0.1 0.063 12.7 0.1 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA PF00004.29 CDJ48595.1 - 0.063 13.7 0.2 0.063 13.7 0.2 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ48595.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CDJ48595.1 - 0.51 10.0 2.3 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain O-antigen_lig PF13425.6 CDJ48596.1 - 0.42 9.3 4.3 0.52 9.0 4.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SR-25 PF10500.9 CDJ48597.1 - 0.8 9.3 35.6 1.4 8.4 26.3 2.8 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.11 CDJ48597.1 - 1.7 7.0 22.8 2.5 6.5 22.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Atx10homo_assoc PF09759.9 CDJ48598.1 - 1.8e-06 27.9 1.4 4.6e-06 26.6 0.0 2.5 2 0 0 2 2 1 1 Spinocerebellar ataxia type 10 protein domain DUF2722 PF10846.8 CDJ48598.1 - 2.4e-05 23.5 37.8 0.032 13.2 5.5 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ48598.1 - 0.00026 20.7 54.3 0.054 13.1 18.3 3.3 3 0 0 3 3 3 3 Spt20 family Spore_coat_CotO PF14153.6 CDJ48598.1 - 0.0048 16.8 4.4 0.0048 16.8 4.4 3.8 3 2 0 3 3 2 1 Spore coat protein CotO Med15 PF09606.10 CDJ48598.1 - 0.027 13.2 45.1 0.025 13.3 9.0 3.3 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal WBP-1 PF11669.8 CDJ48598.1 - 0.029 15.0 1.6 0.029 15.0 1.6 3.6 3 0 0 3 3 3 0 WW domain-binding protein 1 RAP1 PF07218.11 CDJ48598.1 - 0.27 9.5 4.6 0.4 8.9 4.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MecA PF05389.12 CDJ48598.1 - 0.33 10.5 10.9 1.9 8.1 1.0 3.4 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) Spike_torovirin PF17072.5 CDJ48598.1 - 0.82 6.7 3.3 1.1 6.3 3.3 1.1 1 0 0 1 1 1 0 Torovirinae spike glycoprotein SARAF PF06682.12 CDJ48598.1 - 1.1 8.9 0.0 1.1 8.9 0.0 3.9 2 2 1 3 3 1 0 SOCE-associated regulatory factor of calcium homoeostasis Connexin PF00029.19 CDJ48598.1 - 1.3 8.8 9.9 14 5.3 0.4 3.9 3 1 0 3 3 3 0 Connexin Methyltransf_23 PF13489.6 CDJ48598.1 - 1.5 8.6 6.5 2.8 7.8 0.4 3.1 3 0 0 3 3 3 0 Methyltransferase domain OmpH PF03938.14 CDJ48598.1 - 5.8 7.3 61.1 1.6 9.1 9.6 4.7 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) CBM_20 PF00686.19 CDJ48599.1 - 3.1e-17 62.3 0.0 4.6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Starch binding domain Ribosomal_60s PF00428.19 CDJ48599.1 - 0.79 10.4 29.5 0.079 13.6 6.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ48600.1 - 2.9e-06 27.7 31.2 0.00053 20.3 1.6 2.4 1 1 1 2 2 2 2 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ48600.1 - 0.026 15.1 5.1 0.026 15.1 5.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein THOC2_N PF16134.5 CDJ48600.1 - 0.053 12.2 25.9 0.052 12.2 3.0 2.0 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus SLC12 PF03522.15 CDJ48600.1 - 0.15 11.1 25.4 0.19 10.7 25.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CD20 PF04103.15 CDJ48600.1 - 0.16 12.1 0.3 0.16 12.1 0.3 2.1 2 0 0 2 2 2 0 CD20-like family MDM10 PF12519.8 CDJ48600.1 - 0.17 10.7 20.2 0.23 10.3 20.2 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4820 PF16091.5 CDJ48600.1 - 0.68 9.3 22.0 0.38 10.1 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) FAM60A PF15396.6 CDJ48600.1 - 0.85 9.6 20.5 1.1 9.3 2.5 2.0 2 0 0 2 2 2 0 Protein Family FAM60A SPG4 PF17325.2 CDJ48600.1 - 1 10.5 23.6 1.5 10.0 5.7 2.2 2 0 0 2 2 2 0 Stationary phase protein 4 DUF719 PF05334.13 CDJ48600.1 - 1.5 9.0 23.4 0.75 10.0 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF719) PRP1_N PF06424.12 CDJ48600.1 - 2.4 8.5 22.9 2.9 8.3 4.6 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Folate_carrier PF01770.18 CDJ48600.1 - 2.7 6.6 18.9 2.8 6.6 2.9 2.0 2 0 0 2 2 2 0 Reduced folate carrier CTNNB1_binding PF08347.11 CDJ48600.1 - 2.9 8.0 20.8 0.94 9.6 3.2 2.1 2 0 0 2 2 2 0 N-terminal CTNNB1 binding CbiD PF01888.17 CDJ48600.1 - 3.2 7.0 16.7 2.2 7.5 8.2 2.2 1 1 1 2 2 2 0 CbiD DUF5094 PF17015.5 CDJ48600.1 - 3.3 7.8 20.0 0.13 12.4 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) FHIPEP PF00771.20 CDJ48600.1 - 3.7 5.9 20.9 2.4 6.5 9.9 2.0 2 0 0 2 2 2 0 FHIPEP family BSMAP PF12280.8 CDJ48600.1 - 4 7.6 25.4 0.52 10.5 3.7 2.1 2 0 0 2 2 2 0 Brain specific membrane anchored protein RNA_pol_Rpc4 PF05132.14 CDJ48600.1 - 4.1 7.8 25.1 0.6 10.5 3.3 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Rxt3 PF08642.10 CDJ48600.1 - 4.5 8.1 18.4 3.9 8.2 2.0 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 eIF-3_zeta PF05091.12 CDJ48600.1 - 4.7 6.1 38.9 2.6 6.9 10.8 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ48600.1 - 5.3 8.1 36.3 7.7 7.6 15.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3408 PF11888.8 CDJ48600.1 - 6.1 7.0 28.7 1.8 8.7 5.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Pal1 PF08316.11 CDJ48600.1 - 6.5 7.5 19.6 7.2 7.4 8.6 2.1 2 0 0 2 2 2 0 Pal1 cell morphology protein TMEM174 PF15029.6 CDJ48600.1 - 6.9 6.3 13.9 5.5 6.6 2.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 174 DUF3984 PF13136.6 CDJ48600.1 - 7.5 5.9 29.0 1.3 8.3 7.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) Connexin PF00029.19 CDJ48600.1 - 7.7 6.2 27.7 6.3 6.5 6.6 2.0 2 0 0 2 2 2 0 Connexin AIF_C PF14721.6 CDJ48600.1 - 8.6 6.7 25.6 7 7.0 5.4 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4407 PF14362.6 CDJ48600.1 - 8.6 5.6 38.4 12 5.1 38.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) G0-G1_switch_2 PF15103.6 CDJ48600.1 - 8.7 6.8 25.1 2.1 8.8 4.3 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 TCP PF03634.13 CDJ48600.1 - 8.8 6.9 30.7 2.8 8.5 7.6 2.1 2 0 0 2 2 2 0 TCP family transcription factor RSB_motif PF16294.5 CDJ48600.1 - 8.8 6.7 28.1 6.6 7.1 5.6 2.1 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif DUF5523 PF17661.1 CDJ48600.1 - 9.2 5.9 33.1 3.8 7.1 8.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5523) SR-25 PF10500.9 CDJ48601.1 - 0.00027 20.6 15.0 0.00027 20.6 15.0 5.6 3 2 0 5 5 5 2 Nuclear RNA-splicing-associated protein Med3 PF11593.8 CDJ48602.1 - 0.32 10.2 4.6 0.3 10.2 4.6 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ48602.1 - 0.74 10.1 17.8 0.94 9.7 17.8 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Peptidase_M17_N PF02789.17 CDJ48602.1 - 2.4 8.0 11.1 3 7.7 11.1 1.1 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain DUF2057 PF09829.9 CDJ48602.1 - 3.3 7.8 6.5 3.6 7.7 6.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF2722 PF10846.8 CDJ48603.1 - 0.0048 15.9 8.4 0.0048 15.9 8.4 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ48603.1 - 0.0052 16.4 10.8 0.0052 16.4 10.8 2.1 2 0 0 2 2 2 1 Spt20 family DUF755 PF05501.11 CDJ48603.1 - 0.025 14.9 9.3 0.025 14.9 9.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) TMEM208_SND2 PF05620.11 CDJ48603.1 - 0.066 13.0 1.1 0.13 12.1 1.1 1.4 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 SR-25 PF10500.9 CDJ48603.1 - 0.1 12.2 37.2 0.05 13.2 10.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CSG2 PF16965.5 CDJ48603.1 - 0.25 10.2 3.6 0.31 9.9 3.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4834 PF16118.5 CDJ48603.1 - 7.2 7.6 11.6 0.1 13.5 2.7 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Helicase_C PF00271.31 CDJ48604.1 - 3.5e-05 24.1 0.0 3.9e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Spt20 PF12090.8 CDJ48605.1 - 0.0014 18.3 28.3 0.0014 18.3 28.3 2.1 2 0 0 2 2 2 1 Spt20 family DcuA_DcuB PF03605.14 CDJ48605.1 - 0.0037 16.2 0.9 0.0049 15.8 0.6 1.3 1 1 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter FHIPEP PF00771.20 CDJ48605.1 - 0.013 14.0 1.9 0.015 13.8 1.9 1.1 1 0 0 1 1 1 0 FHIPEP family CoaE PF01121.20 CDJ48605.1 - 0.02 14.5 5.1 0.027 14.1 5.1 1.1 1 0 0 1 1 1 0 Dephospho-CoA kinase DUF4834 PF16118.5 CDJ48605.1 - 0.043 14.8 8.8 0.043 14.8 8.8 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ48605.1 - 0.071 12.9 7.0 0.11 12.3 6.9 1.5 1 1 0 1 1 1 0 Connexin O-antigen_lig PF13425.6 CDJ48605.1 - 0.074 11.8 0.9 0.081 11.7 0.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Adenyl_cycl_N PF12633.7 CDJ48605.1 - 0.081 12.8 10.6 0.097 12.6 10.5 1.3 1 1 0 1 1 1 0 Adenylate cyclase NT domain DUF3169 PF11368.8 CDJ48605.1 - 0.087 12.3 0.0 0.094 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Tmp39 PF10271.9 CDJ48605.1 - 0.11 11.4 1.7 0.13 11.2 1.7 1.1 1 0 0 1 1 1 0 Putative transmembrane protein Menin PF05053.13 CDJ48605.1 - 0.16 10.3 14.8 0.17 10.2 14.8 1.2 1 0 0 1 1 1 0 Menin FDC-SP PF15215.6 CDJ48605.1 - 0.17 12.4 1.5 20 5.8 0.0 2.4 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide DUF4407 PF14362.6 CDJ48605.1 - 0.21 10.9 9.8 0.25 10.6 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SPX PF03105.19 CDJ48605.1 - 0.23 11.3 24.4 0.25 11.2 24.4 1.0 1 0 0 1 1 1 0 SPX domain RskA PF10099.9 CDJ48605.1 - 0.27 11.5 5.4 0.4 10.9 5.4 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA V_ATPase_I PF01496.19 CDJ48605.1 - 0.3 9.0 9.5 0.33 8.8 9.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ureide_permease PF07168.11 CDJ48605.1 - 0.36 9.5 3.9 0.49 9.1 3.9 1.3 1 0 0 1 1 1 0 Ureide permease PepSY_TM PF03929.16 CDJ48605.1 - 0.53 9.9 1.6 0.54 9.9 1.6 1.2 1 0 0 1 1 1 0 PepSY-associated TM region SID-1_RNA_chan PF13965.6 CDJ48605.1 - 0.76 8.1 8.6 0.92 7.8 8.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NEMP PF10225.9 CDJ48605.1 - 0.97 9.1 10.8 1.3 8.6 10.8 1.3 1 0 0 1 1 1 0 NEMP family CSG2 PF16965.5 CDJ48605.1 - 1.5 7.7 11.4 1.2 8.0 10.2 1.4 1 1 1 2 2 2 0 Ceramide synthase regulator Alpha_GJ PF03229.13 CDJ48605.1 - 1.6 9.3 9.8 5.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J Cellulose_synt PF03552.14 CDJ48605.1 - 1.7 7.1 4.1 1.7 7.0 4.1 1.1 1 0 0 1 1 1 0 Cellulose synthase Mucin PF01456.17 CDJ48605.1 - 1.9 8.5 19.5 1.2 9.1 17.8 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein Paramyxo_ncap PF00973.19 CDJ48605.1 - 2.7 6.8 12.1 2.5 6.9 12.1 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein BRF1 PF07741.13 CDJ48605.1 - 2.7 8.4 13.4 7.4 7.0 12.0 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF572 PF04502.13 CDJ48605.1 - 2.9 7.4 21.2 3.9 7.0 21.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAT1 PF09770.9 CDJ48605.1 - 2.9 6.0 21.3 3.5 5.8 21.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pannexin_like PF12534.8 CDJ48605.1 - 3 6.8 15.6 1.1 8.2 12.4 1.7 1 1 1 2 2 2 0 Pannexin-like TM region of LRRC8 G0-G1_switch_2 PF15103.6 CDJ48605.1 - 3.2 8.2 13.6 0.3 11.5 8.3 1.9 1 1 1 2 2 2 0 G0/G1 switch protein 2 Cwf_Cwc_15 PF04889.12 CDJ48605.1 - 3.4 7.3 20.6 5.2 6.7 19.3 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 CDJ48605.1 - 5.1 6.7 15.9 0.48 10.1 10.8 2.0 1 1 1 2 2 2 0 FAM176 family YfhO PF09586.10 CDJ48605.1 - 5.3 5.1 11.8 5.6 5.1 11.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Med24_N PF11277.8 CDJ48605.1 - 6.7 4.6 14.8 9.4 4.1 14.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal XRN_M PF17846.1 CDJ48605.1 - 7.7 5.3 11.3 11 4.9 11.3 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Hid1 PF12722.7 CDJ48605.1 - 8.6 4.3 19.7 9.7 4.2 19.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HGTP_anticodon2 PF12745.7 CDJ48606.1 - 0.046 13.2 7.0 0.054 13.0 7.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs TRI12 PF06609.13 CDJ48606.1 - 0.098 11.1 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Exonuc_VII_L PF02601.15 CDJ48606.1 - 0.15 11.6 12.3 0.17 11.4 12.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PP2C_C PF07830.13 CDJ48606.1 - 0.22 12.0 2.5 0.46 11.0 2.5 1.5 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Vac7 PF12751.7 CDJ48606.1 - 0.35 10.3 3.6 0.4 10.1 3.6 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 TAF4 PF05236.14 CDJ48606.1 - 0.48 10.1 11.3 0.62 9.8 11.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Presenilin PF01080.17 CDJ48606.1 - 0.51 9.0 8.5 0.58 8.9 8.5 1.1 1 0 0 1 1 1 0 Presenilin Aconitase_2_N PF06434.13 CDJ48606.1 - 1.8 8.1 3.6 0.43 10.2 0.5 1.5 2 0 0 2 2 2 0 Aconitate hydratase 2 N-terminus MAT1 PF06391.13 CDJ48606.1 - 2 8.2 14.2 2.8 7.7 14.2 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 RR_TM4-6 PF06459.12 CDJ48606.1 - 4.1 7.1 8.8 5.7 6.7 8.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4638 PF15472.6 CDJ48607.1 - 0.76 9.5 10.1 0.78 9.4 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF702 PF05142.12 CDJ48607.1 - 8.2 6.9 18.2 18 5.8 18.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF702) DUF1616 PF07760.11 CDJ48607.1 - 10 5.4 9.1 12 5.2 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) YqzE PF14038.6 CDJ48608.1 - 0.93 9.5 0.0 0.93 9.5 0.0 2.0 2 0 0 2 2 2 0 YqzE-like protein O-antigen_lig PF13425.6 CDJ48609.1 - 0.00036 19.5 2.2 0.00043 19.2 2.2 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Kei1 PF08552.11 CDJ48609.1 - 0.0014 18.6 2.0 0.0019 18.1 2.0 1.3 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF3810 PF12725.7 CDJ48609.1 - 0.0025 17.2 2.1 0.0031 16.9 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) HCO3_cotransp PF00955.21 CDJ48609.1 - 0.0025 16.7 0.8 0.003 16.4 0.8 1.1 1 0 0 1 1 1 1 HCO3- transporter family Serinc PF03348.15 CDJ48609.1 - 0.0033 16.4 4.4 0.0042 16.1 4.4 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) CDC45 PF02724.14 CDJ48609.1 - 0.011 14.1 11.8 0.012 13.9 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein GNAT_acetyltr_2 PF13718.6 CDJ48609.1 - 0.011 15.1 10.9 0.012 15.0 10.9 1.0 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF2828 PF11443.8 CDJ48609.1 - 0.014 13.6 11.6 0.015 13.5 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Isy1 PF06246.12 CDJ48609.1 - 0.017 14.7 16.8 0.02 14.5 16.8 1.0 1 0 0 1 1 1 0 Isy1-like splicing family SLC12 PF03522.15 CDJ48609.1 - 0.046 12.7 13.7 0.051 12.6 13.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Tfb4 PF03850.14 CDJ48609.1 - 0.048 13.2 9.5 0.061 12.8 9.5 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF2339 PF10101.9 CDJ48609.1 - 0.068 11.7 6.2 0.093 11.3 6.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Velvet PF11754.8 CDJ48609.1 - 0.081 12.9 11.2 0.11 12.5 11.2 1.1 1 0 0 1 1 1 0 Velvet factor Hid1 PF12722.7 CDJ48609.1 - 0.093 10.9 12.1 0.12 10.5 12.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CstA PF02554.14 CDJ48609.1 - 0.099 11.5 0.2 0.15 10.9 0.0 1.4 1 1 0 1 1 1 0 Carbon starvation protein CstA Endostatin PF06482.11 CDJ48609.1 - 0.1 12.1 12.6 0.13 11.8 12.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin EptA_B_N PF08019.12 CDJ48609.1 - 0.12 12.3 2.6 0.15 11.9 2.6 1.1 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB PIP5K PF01504.18 CDJ48609.1 - 0.22 10.7 9.6 0.29 10.3 9.6 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF913 PF06025.12 CDJ48609.1 - 0.23 10.4 9.7 0.25 10.3 9.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 CDJ48609.1 - 0.28 10.4 14.7 0.12 11.5 7.5 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF2871 PF11070.8 CDJ48609.1 - 0.29 11.4 6.3 0.34 11.2 5.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2871) FliP PF00813.20 CDJ48609.1 - 0.3 10.9 7.8 0.46 10.3 7.8 1.3 1 0 0 1 1 1 0 FliP family SID-1_RNA_chan PF13965.6 CDJ48609.1 - 0.31 9.4 12.5 0.46 8.8 12.5 1.3 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 CDJ48609.1 - 0.33 10.1 11.5 0.43 9.8 11.5 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter Sulf_transp PF04143.14 CDJ48609.1 - 0.37 10.3 5.4 0.42 10.1 5.2 1.4 1 1 0 1 1 1 0 Sulphur transport DDHD PF02862.17 CDJ48609.1 - 0.38 10.9 13.8 0.58 10.3 13.8 1.3 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.6 CDJ48609.1 - 0.41 10.6 11.7 0.49 10.4 11.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Tad PF13400.6 CDJ48609.1 - 0.46 10.8 7.6 10 6.5 6.5 2.7 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like ODV-E18 PF10717.9 CDJ48609.1 - 0.48 10.3 2.1 0.73 9.7 2.1 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Tim54 PF11711.8 CDJ48609.1 - 0.59 8.9 14.3 0.75 8.5 14.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TCP PF03634.13 CDJ48609.1 - 0.63 10.6 17.1 0.91 10.1 17.1 1.2 1 0 0 1 1 1 0 TCP family transcription factor CSRNP_N PF16019.5 CDJ48609.1 - 0.95 9.3 15.7 1.4 8.8 15.7 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF1980 PF09323.10 CDJ48609.1 - 1.1 9.2 14.0 2.8 7.8 14.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) AGTRAP PF06396.11 CDJ48609.1 - 1.2 9.0 7.2 0.044 13.6 0.8 1.8 1 1 1 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Peptidase_M56 PF05569.11 CDJ48609.1 - 1.2 8.3 12.9 0.015 14.5 4.3 2.0 1 1 1 2 2 2 0 BlaR1 peptidase M56 AMP-binding PF00501.28 CDJ48609.1 - 1.3 7.6 3.8 1.5 7.4 3.8 1.2 1 0 0 1 1 1 0 AMP-binding enzyme PepSY_TM PF03929.16 CDJ48609.1 - 1.3 8.7 10.6 0.11 12.2 5.2 2.0 2 0 0 2 2 2 0 PepSY-associated TM region PRA1 PF03208.19 CDJ48609.1 - 1.5 8.5 6.3 2.1 8.0 6.3 1.3 1 0 0 1 1 1 0 PRA1 family protein Lin-8 PF03353.15 CDJ48609.1 - 1.7 8.1 24.5 2.2 7.8 24.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF898 PF05987.13 CDJ48609.1 - 2.2 7.2 6.8 0.66 9.0 4.0 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) ALMT PF11744.8 CDJ48609.1 - 2.3 6.9 15.0 2.9 6.6 15.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter MAP17 PF15807.5 CDJ48609.1 - 3.5 7.9 25.6 9 6.5 25.6 1.7 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4638 PF15472.6 CDJ48609.1 - 3.6 7.3 16.2 3.8 7.2 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Plasmodium_Vir PF05795.11 CDJ48609.1 - 3.8 6.8 9.5 4.2 6.7 9.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.12 CDJ48609.1 - 4.1 6.3 22.3 4.9 6.0 22.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM176 PF14851.6 CDJ48609.1 - 4.2 7.0 16.7 0.79 9.4 9.3 2.4 2 0 0 2 2 2 0 FAM176 family AIF_C PF14721.6 CDJ48609.1 - 4.7 7.6 16.6 24 5.3 16.6 2.1 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term V_ATPase_I PF01496.19 CDJ48609.1 - 6.1 4.6 28.2 19 3.0 28.2 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family SUFU_C PF12470.8 CDJ48609.1 - 6.3 6.8 16.3 10 6.1 16.3 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Nucleoside_tran PF01733.18 CDJ48609.1 - 6.6 6.0 12.3 20 4.4 12.4 1.7 1 1 0 1 1 1 0 Nucleoside transporter Peptidase_S49_N PF08496.10 CDJ48609.1 - 7 6.7 25.8 7.3 6.6 18.9 2.1 1 1 1 2 2 2 0 Peptidase family S49 N-terminal DUF1345 PF07077.11 CDJ48609.1 - 7.1 6.3 8.0 0.34 10.6 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) Peptidase_S15 PF02129.18 CDJ48609.1 - 7.6 6.0 14.1 9.5 5.7 14.1 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4307 PF14155.6 CDJ48609.1 - 10 6.0 8.0 7.3 6.5 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) Draxin PF15550.6 CDJ48610.1 - 0.15 11.9 19.2 0.031 14.2 3.7 2.2 2 0 0 2 2 2 0 Draxin CDC45 PF02724.14 CDJ48611.1 - 0.086 11.1 35.0 0.095 11.0 35.0 1.0 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 CDJ48611.1 - 4.7 7.1 37.6 5.9 6.7 37.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Velvet PF11754.8 CDJ48611.1 - 4.8 7.0 34.1 8.3 6.3 34.1 1.4 1 1 0 1 1 1 0 Velvet factor VIR_N PF15912.5 CDJ48611.1 - 6.2 6.3 25.3 7.8 6.0 25.3 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal PAT1 PF09770.9 CDJ48611.1 - 9.4 4.4 60.3 12 4.1 60.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Auxin_canalis PF05703.11 CDJ48611.1 - 9.6 6.1 16.1 12 5.8 16.1 1.2 1 0 0 1 1 1 0 Auxin canalisation S1 PF00575.23 CDJ48613.1 - 5.9e-06 26.5 0.0 62 4.0 0.0 7.4 8 0 0 8 8 8 4 S1 RNA binding domain Presenilin PF01080.17 CDJ48614.1 - 0.0059 15.4 1.6 0.0062 15.4 1.6 1.2 1 0 0 1 1 1 1 Presenilin Med15 PF09606.10 CDJ48614.1 - 0.01 14.5 18.6 0.015 14.1 18.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.13 CDJ48614.1 - 0.031 14.9 13.1 0.031 14.9 13.1 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ48614.1 - 0.032 13.9 27.5 0.033 13.8 26.2 1.6 2 0 0 2 2 2 0 Spt20 family Neur_chan_memb PF02932.16 CDJ48614.1 - 0.054 13.6 1.0 0.06 13.4 1.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ48614.1 - 0.078 12.0 1.2 0.1 11.7 1.2 1.1 1 0 0 1 1 1 0 CLN3 protein TFIIA PF03153.13 CDJ48614.1 - 0.16 12.0 23.8 0.027 14.5 20.6 1.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 CDJ48614.1 - 0.19 11.9 5.4 0.18 12.0 3.7 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Peroxin-13_N PF04088.13 CDJ48614.1 - 0.24 11.7 3.4 0.24 11.7 2.0 1.6 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Roughex PF06020.11 CDJ48614.1 - 0.26 10.3 8.5 0.37 9.8 8.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein CobT PF06213.12 CDJ48614.1 - 0.85 9.0 12.9 0.22 10.9 9.7 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT TERB2 PF15101.6 CDJ48614.1 - 1.1 9.3 11.9 0.99 9.4 10.5 1.6 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4834 PF16118.5 CDJ48614.1 - 1.1 10.2 10.9 0.077 14.0 5.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) FAM60A PF15396.6 CDJ48614.1 - 1.3 8.9 6.1 0.95 9.4 4.4 1.5 2 0 0 2 2 2 0 Protein Family FAM60A Band_3_cyto PF07565.13 CDJ48614.1 - 1.7 8.4 7.9 2.5 7.8 7.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2722 PF10846.8 CDJ48614.1 - 1.9 7.4 29.1 0.14 11.1 24.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Orf78 PF06024.12 CDJ48614.1 - 4.8 7.5 6.0 7.5 6.9 4.6 1.8 2 0 0 2 2 2 0 Orf78 (ac78) EIIBC-GUT_N PF03612.14 CDJ48614.1 - 5.9 6.6 12.7 0.37 10.5 8.0 1.4 2 0 0 2 2 1 0 Sorbitol phosphotransferase enzyme II N-terminus WASH-7_C PF14746.6 CDJ48614.1 - 6.9 6.3 10.5 0.5 10.0 6.0 1.4 2 0 0 2 2 1 0 WASH complex subunit 7, C-terminal AIF_C PF14721.6 CDJ48614.1 - 9.9 6.5 8.2 0.92 9.9 3.3 1.7 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ins_P5_2-kin PF06090.12 CDJ48615.1 - 0.00018 21.1 23.8 0.00022 20.8 21.6 2.1 2 0 0 2 2 2 1 Inositol-pentakisphosphate 2-kinase SR-25 PF10500.9 CDJ48615.1 - 0.0036 17.0 15.0 0.0036 17.0 15.0 4.8 3 2 1 4 4 4 1 Nuclear RNA-splicing-associated protein Shadoo PF14999.6 CDJ48615.1 - 0.064 13.3 0.4 0.064 13.3 0.4 9.1 5 2 3 8 8 8 0 Shadow of prion protein, neuroprotective Cwf_Cwc_15 PF04889.12 CDJ48616.1 - 4.6e-20 72.4 33.3 7.6e-12 45.5 6.2 2.0 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 CDJ48616.1 - 0.056 13.3 19.1 0.072 12.9 19.1 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing CDC45 PF02724.14 CDJ48616.1 - 0.088 11.1 11.2 0.087 11.1 11.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 CDJ48616.1 - 0.38 11.0 14.7 0.51 10.6 14.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 AUX_IAA PF02309.16 CDJ48616.1 - 0.49 10.2 10.7 1.3 8.8 10.7 1.7 1 1 0 1 1 1 0 AUX/IAA family DUF413 PF04219.12 CDJ48616.1 - 0.56 10.3 3.7 0.61 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF RskA PF10099.9 CDJ48616.1 - 1 9.6 23.2 0.094 13.0 9.6 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA ETRAMP PF09716.10 CDJ48616.1 - 1.1 9.4 3.6 9.1 6.4 0.5 2.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF5427 PF10310.9 CDJ48616.1 - 1.9 7.4 15.6 2.4 7.0 15.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Vir_act_alpha_C PF10400.9 CDJ48616.1 - 5 7.9 10.3 4 8.2 0.2 2.3 2 0 0 2 2 2 0 Virulence activator alpha C-term K_channel_TID PF07941.11 CDJ48616.1 - 5 7.7 24.8 0.27 11.7 9.7 2.9 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Hid1 PF12722.7 CDJ48616.1 - 6 4.9 9.4 6.7 4.7 9.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VIR_N PF15912.5 CDJ48616.1 - 6.9 6.2 8.1 8.5 5.9 8.1 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF1980 PF09323.10 CDJ48617.1 - 0.015 15.2 1.5 0.053 13.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Secretin_N_2 PF07655.13 CDJ48617.1 - 0.026 15.1 4.6 0.026 15.1 4.6 3.9 3 1 0 3 3 3 0 Secretin N-terminal domain AAA_23 PF13476.6 CDJ48617.1 - 0.14 12.6 5.8 0.22 12.0 5.8 1.2 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.13 CDJ48617.1 - 0.41 11.3 16.1 0.31 11.7 10.4 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med13_C PF06333.12 CDJ48617.1 - 1.1 8.5 10.6 0.097 11.9 0.5 2.3 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain SpoIIIAH PF12685.7 CDJ48617.1 - 3.8 7.3 11.9 21 4.8 0.1 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein RR_TM4-6 PF06459.12 CDJ48618.1 - 0.092 12.6 38.5 0.1 12.4 38.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ48618.1 - 0.18 10.5 48.2 0.21 10.3 48.2 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CDJ48618.1 - 0.28 9.9 36.4 0.32 9.7 36.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 CDJ48618.1 - 0.45 9.5 42.0 0.51 9.3 42.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 MDM10 PF12519.8 CDJ48618.1 - 0.98 8.2 35.0 1.1 8.0 35.0 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF3295 PF11702.8 CDJ48618.1 - 1.2 8.4 36.7 1.6 8.0 36.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) FAM60A PF15396.6 CDJ48618.1 - 1.2 9.0 33.1 1.6 8.7 33.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PA26 PF04636.13 CDJ48618.1 - 1.4 7.8 31.5 1.5 7.6 31.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4045 PF13254.6 CDJ48618.1 - 1.7 8.2 35.0 2 8.0 35.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Rtf2 PF04641.12 CDJ48618.1 - 3 7.1 37.8 3.9 6.8 37.8 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger MRI PF15325.6 CDJ48618.1 - 5 8.3 13.5 7 7.8 13.5 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection DUF2052 PF09747.9 CDJ48618.1 - 5.9 7.0 41.8 7.2 6.7 41.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4569 PF15133.6 CDJ48618.1 - 6.9 6.3 40.8 7.6 6.2 40.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) ALMT PF11744.8 CDJ48618.1 - 7.2 5.3 34.1 8.6 5.1 34.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Pentapeptide PF00805.22 CDJ48619.1 - 1.7e-27 94.6 1.8 1.2e-05 24.8 0.0 7.5 3 1 4 8 8 8 6 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 CDJ48619.1 - 7.6e-11 42.0 0.0 0.05 13.8 0.0 4.5 2 2 2 4 4 4 3 Pentapeptide repeats (9 copies) MxiM PF11441.8 CDJ48619.1 - 3.4 8.0 7.4 36 4.7 0.1 3.9 1 1 2 3 3 3 0 Pilot protein MxiM Aminotran_5 PF00266.19 CDJ48620.1 - 5.5e-18 65.1 0.0 8.9e-13 47.9 0.0 4.0 1 1 1 2 2 2 2 Aminotransferase class-V RskA PF10099.9 CDJ48620.1 - 1.5 9.1 67.3 5.8 7.2 0.1 4.3 3 1 0 3 3 3 0 Anti-sigma-K factor rskA Tub PF01167.18 CDJ48620.1 - 2 8.1 9.1 0.73 9.5 4.0 2.5 2 1 1 3 3 3 0 Tub family Spt20 PF12090.8 CDJ48620.1 - 2.4 7.7 58.3 0.041 13.5 13.4 3.2 3 0 0 3 3 3 0 Spt20 family Suf PF05843.14 CDJ48620.1 - 2.4 8.1 26.0 3 7.7 1.7 3.3 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) IHABP4_N PF16174.5 CDJ48620.1 - 9.1 6.9 41.1 13 6.3 19.1 3.6 3 0 0 3 3 3 0 Intracellular hyaluronan-binding protein 4 N-terminal NOA36 PF06524.12 CDJ48621.1 - 1.1e-05 24.9 15.2 0.00023 20.6 10.8 2.6 2 0 0 2 2 2 2 NOA36 protein CENP-B_dimeris PF09026.10 CDJ48621.1 - 0.094 13.1 23.1 0.52 10.7 22.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GCIP PF13324.6 CDJ48621.1 - 1.1 8.9 9.3 2.1 7.9 9.3 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 CDJ48621.1 - 1.7 6.7 20.7 3.2 5.7 20.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 CDJ48621.1 - 5.3 6.2 7.0 11 5.1 7.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.10 CDJ48621.1 - 5.6 6.2 0.0 0.16 11.3 5.2 4.6 2 1 1 4 4 4 0 BUD22 PPP4R2 PF09184.11 CDJ48621.1 - 8.2 5.9 24.1 1.1 8.8 0.4 3.3 3 0 0 3 3 3 0 PPP4R2 TipE PF16972.5 CDJ48622.1 - 0.019 14.2 3.8 0.028 13.6 3.8 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE TRM13 PF05206.14 CDJ48623.1 - 0.0013 18.3 3.5 0.0017 17.9 3.5 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 Band_3_cyto PF07565.13 CDJ48623.1 - 0.039 13.8 4.2 0.055 13.3 4.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 CDJ48623.1 - 0.7 9.9 3.5 0.88 9.6 3.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAP PF07174.11 CDJ48623.1 - 7.1 6.0 29.1 15 5.0 29.1 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Syja_N PF02383.18 CDJ48624.1 - 5.4e-15 55.5 6.8 4.2e-13 49.3 0.1 3.3 3 1 0 3 3 3 2 SacI homology domain PI3K_1B_p101 PF10486.9 CDJ48624.1 - 0.0014 16.5 5.4 0.0014 16.5 5.4 2.2 2 0 0 2 2 2 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit O-antigen_lig PF13425.6 CDJ48624.1 - 0.35 9.6 1.0 0.56 8.9 1.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ORC_WH_C PF18137.1 CDJ48625.1 - 0.028 14.5 6.0 0.041 13.9 6.0 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Suf PF05843.14 CDJ48625.1 - 0.03 14.3 17.5 0.034 14.1 17.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ48625.1 - 0.19 10.5 11.1 0.21 10.3 11.1 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ48625.1 - 0.23 11.5 9.3 0.25 11.4 9.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RusA PF05866.11 CDJ48625.1 - 0.93 10.0 10.2 0.059 13.9 4.3 1.8 2 0 0 2 2 2 0 Endodeoxyribonuclease RusA MecA PF05389.12 CDJ48625.1 - 1.7 8.2 9.6 2.2 7.8 9.6 1.3 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF2076 PF09849.9 CDJ48625.1 - 3.7 7.5 36.1 4.7 7.2 36.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TMEM51 PF15345.6 CDJ48625.1 - 8.8 6.1 17.4 9.3 6.0 0.3 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 PX PF00787.24 CDJ48626.1 - 3.3e-16 59.3 0.6 5.4e-15 55.4 0.0 2.8 2 0 0 2 2 2 1 PX domain NAM-associated PF14303.6 CDJ48626.1 - 9.5e-06 26.4 36.1 6.8e-05 23.7 0.0 6.9 5 3 2 7 7 7 1 No apical meristem-associated C-terminal domain SUIM_assoc PF16619.5 CDJ48626.1 - 0.00016 21.7 1.1 0.00016 21.7 1.1 16.1 10 5 1 11 11 11 1 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ48626.1 - 0.0083 15.8 4.3 0.0083 15.8 4.3 8.1 6 1 0 7 7 7 1 Nuclear RNA-splicing-associated protein PTPRCAP PF15713.5 CDJ48626.1 - 0.035 14.4 0.0 0.035 14.4 0.0 6.2 4 3 1 5 5 5 0 Protein tyrosine phosphatase receptor type C-associated Ras PF00071.22 CDJ48627.1 - 7.5e-17 61.4 0.0 1.8e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CDJ48627.1 - 4.3e-09 36.6 0.0 0.0043 17.3 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ48627.1 - 0.011 15.2 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family GREB1 PF15782.5 CDJ48628.1 - 1.4 6.0 13.8 1.4 5.9 13.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 CDJ48628.1 - 3.1 6.7 11.5 3.5 6.5 11.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 CDJ48628.1 - 3.2 5.7 14.7 3.5 5.6 14.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.12 CDJ48628.1 - 7.3 6.8 13.4 9.1 6.5 13.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Macoilin PF09726.9 CDJ48629.1 - 0.00062 18.5 11.4 0.00095 17.9 11.4 1.2 1 0 0 1 1 1 1 Macoilin family PI3K_1B_p101 PF10486.9 CDJ48629.1 - 8.3 4.0 12.9 13 3.4 12.9 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pkinase PF00069.25 CDJ48630.1 - 1.1e-30 107.0 0.0 1.1e-17 64.3 0.0 3.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ48630.1 - 2e-09 37.1 0.0 0.0034 16.7 0.0 3.8 3 0 0 3 3 3 3 Protein tyrosine kinase SUIM_assoc PF16619.5 CDJ48630.1 - 0.0087 16.1 1.2 0.0087 16.1 1.2 6.5 5 2 0 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 DUF5094 PF17015.5 CDJ48630.1 - 0.78 9.8 5.5 2.7 8.1 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) SR-25 PF10500.9 CDJ48631.1 - 4.2 6.9 57.1 0.2 11.2 14.6 4.9 3 1 1 4 4 4 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ48632.1 - 0.11 12.6 12.8 0.24 11.5 12.8 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF1980 PF09323.10 CDJ48632.1 - 0.56 10.1 4.3 1.5 8.7 4.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DEAD PF00270.29 CDJ48633.1 - 0.00039 20.2 0.1 0.0015 18.3 0.1 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ48633.1 - 0.0018 18.3 0.0 0.0018 18.3 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF4064 PF13273.6 CDJ48633.1 - 0.55 10.5 2.3 2.4 8.5 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) TAS2R PF05296.13 CDJ48633.1 - 0.69 9.0 2.1 1 8.4 2.1 1.2 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) Connexin PF00029.19 CDJ48633.1 - 1.2 8.8 5.1 4.4 7.0 0.7 2.7 2 0 0 2 2 2 0 Connexin Renin_r PF07850.14 CDJ48633.1 - 2 9.1 5.1 3.9 8.1 0.4 3.3 2 0 0 2 2 2 0 Renin receptor-like protein SR-25 PF10500.9 CDJ48634.1 - 0.0071 16.0 18.0 0.0078 15.9 18.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SID-1_RNA_chan PF13965.6 CDJ48634.1 - 0.71 8.2 7.4 0.81 8.0 7.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF-3_zeta PF05091.12 CDJ48634.1 - 1.3 7.9 26.8 1.3 7.9 26.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.14 CDJ48634.1 - 2.2 6.5 19.9 2.3 6.4 19.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Velvet PF11754.8 CDJ48634.1 - 2.2 8.2 23.1 2.3 8.1 23.1 1.2 1 0 0 1 1 1 0 Velvet factor SMYLE_N PF18615.1 CDJ48634.1 - 2.2 7.7 21.8 2.5 7.6 21.8 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain FAM60A PF15396.6 CDJ48634.1 - 2.3 8.2 17.5 2.6 8.0 17.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Endostatin PF06482.11 CDJ48634.1 - 2.4 7.5 19.7 2.5 7.5 19.7 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin TFIIA PF03153.13 CDJ48634.1 - 2.5 8.0 58.3 2.9 7.8 58.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ48634.1 - 2.7 7.7 27.2 2.9 7.6 27.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ48634.1 - 2.9 7.9 17.4 3 7.8 17.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ48634.1 - 3.3 6.4 32.5 3.5 6.3 32.5 1.1 1 0 0 1 1 1 0 Presenilin SprA-related PF12118.8 CDJ48634.1 - 3.4 6.7 53.9 4.3 6.4 53.9 1.1 1 0 0 1 1 1 0 SprA-related family DUF913 PF06025.12 CDJ48634.1 - 3.8 6.4 16.6 3.9 6.3 16.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) VIR_N PF15912.5 CDJ48634.1 - 4.6 6.8 11.5 5.1 6.6 11.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal MAJIN PF15077.6 CDJ48634.1 - 5.2 6.8 17.6 5.7 6.7 17.6 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein PPP4R2 PF09184.11 CDJ48634.1 - 5.3 6.5 15.4 5.7 6.4 15.4 1.0 1 0 0 1 1 1 0 PPP4R2 NARP1 PF12569.8 CDJ48634.1 - 5.5 5.8 22.6 6.7 5.5 22.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PA26 PF04636.13 CDJ48634.1 - 6.3 5.6 19.5 6.4 5.6 19.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HemX PF04375.14 CDJ48634.1 - 6.3 6.0 46.2 7.3 5.8 46.2 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase V_ATPase_I PF01496.19 CDJ48634.1 - 6.7 4.5 20.7 7.2 4.4 20.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCSAP PF15748.5 CDJ48634.1 - 6.7 6.8 28.0 8.3 6.5 28.0 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Lin-8 PF03353.15 CDJ48634.1 - 7.3 6.0 27.3 8.1 5.9 27.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 CDJ48634.1 - 7.7 5.4 23.3 7.8 5.4 23.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 MMR1 PF08505.10 CDJ48634.1 - 9.2 6.5 30.3 10 6.3 30.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF2828 PF11443.8 CDJ48634.1 - 9.9 4.1 19.1 10 4.1 19.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SR-25 PF10500.9 CDJ48635.1 - 1.8e-05 24.5 35.9 1.8e-05 24.5 35.9 2.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein SSP160 PF06933.11 CDJ48635.1 - 0.27 9.4 10.8 0.32 9.1 10.8 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pex14_N PF04695.13 CDJ48636.1 - 4.2 8.0 27.5 4.3 8.0 27.5 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Orf78 PF06024.12 CDJ48636.1 - 5.9 7.2 6.9 8.6 6.7 6.9 1.4 1 0 0 1 1 1 0 Orf78 (ac78) RAP1 PF07218.11 CDJ48637.1 - 1 7.5 5.1 1 7.6 5.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SprA-related PF12118.8 CDJ48637.1 - 1.2 8.2 17.7 1.3 8.1 17.7 1.0 1 0 0 1 1 1 0 SprA-related family DUF4794 PF16042.5 CDJ48637.1 - 5.9 8.0 7.9 2.6 9.1 5.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4794) Pex14_N PF04695.13 CDJ48637.1 - 7 7.3 16.4 9.3 6.9 16.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2353 PF09789.9 CDJ48639.1 - 0.00056 19.4 14.1 0.0007 19.0 14.1 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) EMP24_GP25L PF01105.24 CDJ48639.1 - 0.0053 16.7 1.7 0.0053 16.7 1.7 2.0 1 1 1 2 2 2 1 emp24/gp25L/p24 family/GOLD CEP63 PF17045.5 CDJ48639.1 - 0.006 16.5 19.6 0.0091 15.9 19.6 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa CLZ PF16526.5 CDJ48639.1 - 0.019 15.3 4.3 0.019 15.3 4.3 1.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Gaa1 PF04114.14 CDJ48639.1 - 0.058 12.4 1.3 0.15 11.1 0.4 1.9 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component XhlA PF10779.9 CDJ48639.1 - 0.21 11.8 2.2 0.44 10.8 0.4 2.1 1 1 1 2 2 2 0 Haemolysin XhlA Neur_chan_memb PF02932.16 CDJ48639.1 - 0.62 10.1 2.6 1 9.3 2.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ERM PF00769.19 CDJ48639.1 - 2.9 7.6 18.3 4.4 7.0 18.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tic110 PF16940.5 CDJ48639.1 - 3.1 6.2 7.2 4.9 5.5 7.2 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF724 PF05266.14 CDJ48639.1 - 3.2 7.5 9.3 4.8 7.0 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phage_GPO PF05929.11 CDJ48639.1 - 3.6 7.2 8.7 5.8 6.5 8.7 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.11 CDJ48639.1 - 5.4 5.8 14.9 9.4 5.0 14.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CDJ48639.1 - 5.5 4.8 5.6 7.1 4.4 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 CDJ48639.1 - 6.1 7.5 26.6 0.77 10.4 12.6 2.6 2 0 0 2 2 2 0 SlyX Dmrt1 PF12374.8 CDJ48639.1 - 7.9 7.0 9.9 2.1 8.9 4.9 2.3 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Tropomyosin_1 PF12718.7 CDJ48639.1 - 9.6 6.4 15.4 0.5 10.5 9.0 1.8 1 1 1 2 2 2 0 Tropomyosin like CAC1F_C PF16885.5 CDJ48640.1 - 0.075 12.7 26.0 0.086 12.5 26.0 1.0 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term BAF1_ABF1 PF04684.13 CDJ48640.1 - 0.23 10.5 26.7 0.32 10.0 26.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SARAF PF06682.12 CDJ48640.1 - 0.24 11.0 26.9 0.32 10.6 26.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Connexin PF00029.19 CDJ48640.1 - 1.9 8.2 27.1 3.6 7.3 5.5 2.1 2 0 0 2 2 2 0 Connexin PvlArgDC PF01862.16 CDJ48640.1 - 2.8 7.7 10.0 0.059 13.2 1.3 2.1 1 1 1 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) LAP1C PF05609.12 CDJ48640.1 - 9.7 5.2 37.0 13 4.7 37.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SPX PF03105.19 CDJ48641.1 - 0.11 12.4 17.6 0.13 12.2 17.6 1.1 1 0 0 1 1 1 0 SPX domain Paramyxo_ncap PF00973.19 CDJ48641.1 - 0.21 10.5 3.5 0.28 10.1 3.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Pro_isomerase PF00160.21 CDJ48642.1 - 1.6e-13 51.3 0.2 1.6e-13 51.3 0.2 2.2 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MTES_1575 PF18741.1 CDJ48642.1 - 0.071 13.3 0.1 0.2 11.8 0.1 1.8 1 0 0 1 1 1 0 REase_MTES_1575 UPF0524 PF15823.5 CDJ48642.1 - 0.96 8.8 8.2 1.5 8.2 1.0 2.3 2 0 0 2 2 2 0 UPF0524 of C3orf70 MAP7 PF05672.11 CDJ48643.1 - 0.82 9.4 63.8 1.1 8.9 63.8 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family CCSAP PF15748.5 CDJ48643.1 - 1 9.5 59.4 1.2 9.2 59.4 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated AF-4 PF05110.13 CDJ48643.1 - 2.9 5.9 55.3 3.5 5.6 55.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ48643.1 - 7.2 6.1 52.6 0.13 11.9 33.8 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein TYW3 PF02676.14 CDJ48644.1 - 0.0018 17.7 0.5 0.0018 17.7 0.5 6.2 2 2 1 4 4 4 1 Methyltransferase TYW3 Pkinase PF00069.25 CDJ48646.1 - 2.6e-14 53.2 0.0 3e-06 26.8 0.0 3.6 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ48646.1 - 4e-07 29.6 0.3 0.0016 17.8 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ48646.1 - 3.9e-06 26.4 0.0 0.0081 15.5 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Miga PF10265.9 CDJ48646.1 - 1.4 7.8 3.6 0.44 9.5 0.6 1.6 2 0 0 2 2 2 0 Mitoguardin Orf78 PF06024.12 CDJ48647.1 - 1.8 8.9 17.1 0.69 10.3 0.2 3.5 3 0 0 3 3 3 0 Orf78 (ac78) UPF0524 PF15823.5 CDJ48648.1 - 0.0062 16.0 0.1 0.0062 16.0 0.1 3.5 2 1 1 3 3 3 1 UPF0524 of C3orf70 Spt20 PF12090.8 CDJ48648.1 - 0.0085 15.7 16.7 0.0085 15.7 16.7 3.8 2 1 0 2 2 2 1 Spt20 family Miff PF05644.11 CDJ48648.1 - 0.012 15.3 1.3 0.012 15.3 1.3 2.8 3 0 0 3 3 3 0 Mitochondrial and peroxisomal fission factor Mff Sin_N PF04801.13 CDJ48648.1 - 4.4 6.4 45.9 0.6 9.3 28.4 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region RskA PF10099.9 CDJ48649.1 - 0.003 17.9 20.2 0.003 17.9 20.2 4.2 1 1 2 3 3 3 1 Anti-sigma-K factor rskA MAM33 PF02330.16 CDJ48649.1 - 0.0089 16.0 10.5 0.0089 16.0 10.5 3.2 2 1 1 3 3 3 1 Mitochondrial glycoprotein DUF3169 PF11368.8 CDJ48649.1 - 0.11 12.0 3.7 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) MAP7 PF05672.11 CDJ48649.1 - 0.25 11.0 51.0 0.11 12.2 16.8 2.7 3 0 0 3 3 3 0 MAP7 (E-MAP-115) family PNISR PF15996.5 CDJ48651.1 - 1.2e-05 25.8 27.8 1.6e-05 25.3 27.8 1.3 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR Stevor PF17410.2 CDJ48651.1 - 0.0032 17.1 2.1 0.005 16.4 2.1 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame CSG2 PF16965.5 CDJ48651.1 - 1.5 7.7 3.3 2.4 7.0 3.3 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator RICTOR_N PF14664.6 CDJ48651.1 - 3.5 6.5 5.1 5.4 5.9 5.1 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Folate_carrier PF01770.18 CDJ48651.1 - 5.5 5.6 5.6 10 4.7 5.6 1.4 1 0 0 1 1 1 0 Reduced folate carrier PAT1 PF09770.9 CDJ48651.1 - 7.6 4.7 24.5 12 4.1 24.5 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LAP1C PF05609.12 CDJ48651.1 - 8.1 5.4 21.0 11 4.9 21.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Tic110 PF16940.5 CDJ48652.1 - 1.5 7.3 12.3 2.5 6.5 12.3 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter Myosin_head PF00063.21 CDJ48653.1 - 3.2e-43 147.9 0.0 4e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 CDJ48653.1 - 9e-06 25.4 0.1 1.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 CDJ48653.1 - 0.0008 19.8 0.0 0.0022 18.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 CDJ48653.1 - 0.0087 16.1 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 CDJ48653.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ48653.1 - 0.024 13.9 0.1 0.046 13.0 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_6 PF12774.7 CDJ48653.1 - 0.024 13.6 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region NACHT PF05729.12 CDJ48653.1 - 0.06 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 CDJ48653.1 - 0.06 13.0 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 CDJ48653.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.9 CDJ48653.1 - 0.069 12.1 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 CDJ48653.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CDJ48653.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDJ48653.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 CDJ48653.1 - 0.14 11.4 0.1 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 CDJ48653.1 - 0.2 11.4 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 CDJ48653.1 - 0.2 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Activator_LAG-3 PF11498.8 CDJ48654.1 - 0.0018 17.3 14.6 0.0018 17.3 14.6 8.8 6 3 2 8 8 8 1 Transcriptional activator LAG-3 DUF3504 PF12012.8 CDJ48655.1 - 0.016 15.1 1.5 0.016 15.1 1.5 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3504) Hamartin PF04388.12 CDJ48655.1 - 0.035 12.8 20.8 0.043 12.5 20.8 1.0 1 0 0 1 1 1 0 Hamartin protein Lin-8 PF03353.15 CDJ48655.1 - 8.4 5.9 32.1 2.4 7.6 0.7 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF2477 PF10631.9 CDJ48656.1 - 0.62 10.7 4.2 0.81 10.3 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) TFIIA PF03153.13 CDJ48656.1 - 0.8 9.6 12.4 0.86 9.5 12.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Bromodomain PF00439.25 CDJ48657.1 - 5.4e-19 68.0 0.0 1e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain Spt20 PF12090.8 CDJ48657.1 - 0.0007 19.3 6.9 0.0007 19.3 6.9 2.1 2 0 0 2 2 2 1 Spt20 family SRP-alpha_N PF04086.13 CDJ48657.1 - 0.018 15.0 8.5 0.023 14.6 0.8 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal MRPL52 PF18699.1 CDJ48657.1 - 0.06 13.5 5.0 0.1 12.8 5.0 1.3 1 0 0 1 1 1 0 Mitoribosomal protein mL52 FlbT PF07378.11 CDJ48657.1 - 0.08 13.0 0.3 0.18 11.9 0.3 1.6 1 0 0 1 1 1 0 Flagellar protein FlbT KGK PF08872.10 CDJ48657.1 - 0.17 12.4 0.7 0.26 11.8 0.7 1.2 1 0 0 1 1 1 0 KGK domain Ctr PF04145.15 CDJ48657.1 - 0.2 12.3 3.2 3.6 8.2 0.1 2.2 2 0 0 2 2 2 0 Ctr copper transporter family BUD22 PF09073.10 CDJ48657.1 - 0.23 10.8 10.7 0.89 8.8 4.2 2.1 2 0 0 2 2 2 0 BUD22 Hid1 PF12722.7 CDJ48657.1 - 0.36 8.9 1.9 1.2 7.2 0.0 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Fe_bilin_red PF05996.12 CDJ48657.1 - 0.41 10.3 7.2 0.61 9.7 7.2 1.2 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase Folliculin PF11704.8 CDJ48657.1 - 0.48 10.3 4.7 0.22 11.4 1.4 1.9 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport SPX PF03105.19 CDJ48657.1 - 2.8 7.8 16.1 5.3 6.9 3.6 2.2 2 0 0 2 2 2 0 SPX domain MAP65_ASE1 PF03999.12 CDJ48657.1 - 3.6 6.2 13.4 1.2 7.8 1.6 2.0 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) MID_MedPIWI PF18296.1 CDJ48657.1 - 4.4 7.0 12.6 13 5.5 0.3 2.3 2 0 0 2 2 2 0 MID domain of medPIWI DUF3439 PF11921.8 CDJ48657.1 - 4.5 7.3 18.5 20 5.2 18.5 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SR-25 PF10500.9 CDJ48657.1 - 5.4 6.6 14.1 1.1 8.8 8.7 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ48657.1 - 5.7 5.7 6.2 4.3 6.1 3.0 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF2722 PF10846.8 CDJ48657.1 - 8.1 5.3 21.0 0.032 13.2 6.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ48657.1 - 8.6 7.4 10.0 1.9 9.5 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ48658.1 - 0.0013 18.8 1.4 0.0013 18.8 1.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ48658.1 - 0.0022 17.0 1.8 0.0023 17.0 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ48658.1 - 0.021 15.1 11.6 0.021 15.1 11.6 2.9 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Roughex PF06020.11 CDJ48658.1 - 0.036 13.2 0.9 0.048 12.8 0.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ48658.1 - 0.1 12.2 11.7 0.15 11.6 11.7 1.2 1 0 0 1 1 1 0 Spt20 family Ribosomal_60s PF00428.19 CDJ48659.1 - 0.73 10.5 6.6 1.7 9.3 6.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Vps54 PF07928.12 CDJ48660.1 - 4.4e-17 62.8 3.6 4.4e-17 62.8 3.6 7.2 7 0 0 7 7 7 1 Vps54-like protein RskA PF10099.9 CDJ48663.1 - 2.2e-06 28.1 11.6 3e-06 27.7 11.6 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA eIF-3_zeta PF05091.12 CDJ48663.1 - 0.005 15.9 3.9 0.005 15.9 3.9 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ48663.1 - 0.047 11.6 5.0 0.056 11.4 5.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Porin_4 PF13609.6 CDJ48663.1 - 0.088 12.5 0.3 0.09 12.5 0.3 1.1 1 0 0 1 1 1 0 Gram-negative porin PEX11 PF05648.14 CDJ48663.1 - 0.1 12.1 1.5 0.14 11.6 1.5 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) CCDC53 PF10152.9 CDJ48663.1 - 0.21 12.0 13.4 1.1 9.7 6.3 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Serinc PF03348.15 CDJ48663.1 - 0.33 9.8 2.1 0.35 9.7 2.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spt20 PF12090.8 CDJ48663.1 - 0.4 10.3 30.0 0.033 13.8 23.8 2.0 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 CDJ48663.1 - 0.65 8.7 13.6 0.04 12.7 7.7 1.6 1 1 0 1 1 1 0 Presenilin FAM176 PF14851.6 CDJ48663.1 - 0.97 9.1 6.7 0.48 10.1 4.6 1.5 2 0 0 2 2 2 0 FAM176 family DUF702 PF05142.12 CDJ48663.1 - 1.2 9.7 12.6 0.46 10.9 7.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF4834 PF16118.5 CDJ48663.1 - 1.7 9.7 14.7 0.3 12.1 8.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ48663.1 - 2 8.2 6.5 3.8 7.2 6.4 1.5 2 0 0 2 2 2 0 Connexin EOS1 PF12326.8 CDJ48663.1 - 4.2 7.3 5.9 5.2 7.0 5.9 1.3 1 1 0 1 1 1 0 N-glycosylation protein V_ATPase_I PF01496.19 CDJ48664.1 - 1.9 6.3 23.8 2.3 6.0 23.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KBP_C PF12309.8 CDJ48664.1 - 5.2 6.5 19.1 0.13 11.7 13.2 1.4 2 0 0 2 2 2 0 KIF-1 binding protein C terminal CDC45 PF02724.14 CDJ48664.1 - 8.5 4.5 17.8 11 4.1 17.8 1.3 1 0 0 1 1 1 0 CDC45-like protein SWI-SNF_Ssr4 PF08549.10 CDJ48664.1 - 9.9 4.7 30.9 11 4.5 30.9 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF677 PF05055.12 CDJ48666.1 - 0.043 12.7 0.1 0.043 12.7 0.1 2.7 3 1 0 4 4 4 0 Protein of unknown function (DUF677) RskA PF10099.9 CDJ48668.1 - 2.4e-08 34.5 9.2 2.4e-08 34.5 9.2 6.5 1 1 4 5 5 5 1 Anti-sigma-K factor rskA Cwf_Cwc_15 PF04889.12 CDJ48668.1 - 0.0081 15.9 18.0 0.0081 15.9 18.0 3.8 3 1 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein DUF3796 PF12676.7 CDJ48668.1 - 0.066 13.7 1.5 0.2 12.1 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) Caldesmon PF02029.15 CDJ48668.1 - 4.7 5.9 66.8 3.5 6.3 32.3 2.3 2 0 0 2 2 2 0 Caldesmon BAF1_ABF1 PF04684.13 CDJ48669.1 - 0.13 11.3 18.6 0.16 11.0 18.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NPR3 PF03666.13 CDJ48669.1 - 0.16 10.7 15.5 0.18 10.5 15.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 CDJ48669.1 - 0.37 9.3 16.1 0.42 9.1 16.1 1.2 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 CDJ48669.1 - 0.49 9.6 10.4 0.55 9.4 10.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1635 PF07795.11 CDJ48669.1 - 0.5 10.2 19.7 0.061 13.2 12.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) SLC12 PF03522.15 CDJ48669.1 - 0.5 9.3 15.5 0.6 9.1 15.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Apt1 PF10351.9 CDJ48669.1 - 0.62 8.8 16.1 0.67 8.7 16.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 CDJ48669.1 - 1.7 6.9 14.9 2.2 6.5 14.9 1.2 1 0 0 1 1 1 0 Menin DAG_kinase_N PF14513.6 CDJ48669.1 - 2 8.6 17.2 0.2 11.9 12.3 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus V_ATPase_I PF01496.19 CDJ48669.1 - 4 5.2 9.9 4.4 5.1 9.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4746 PF15928.5 CDJ48669.1 - 4.8 6.5 9.3 4.8 6.5 8.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) Hid1 PF12722.7 CDJ48669.1 - 4.8 5.2 20.8 5.6 5.0 20.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4718 PF15842.5 CDJ48669.1 - 5 6.9 14.2 2.2 8.1 11.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4718) SAPS PF04499.15 CDJ48669.1 - 6.1 5.5 12.9 6.5 5.4 12.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2561 PF10812.8 CDJ48669.1 - 6.7 6.7 7.6 12 5.9 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Nrf1_activ_bdg PF10492.9 CDJ48669.1 - 8.6 7.1 19.5 4.1 8.1 3.1 3.2 3 0 0 3 3 3 0 Nrf1 activator activation site binding domain Miga PF10265.9 CDJ48669.1 - 9.2 5.1 16.5 9.9 5.0 16.5 1.1 1 0 0 1 1 1 0 Mitoguardin CytochromB561_N PF09786.9 CDJ48669.1 - 9.8 5.0 21.1 12 4.8 21.1 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal XRN_M PF17846.1 CDJ48669.1 - 10 5.0 12.1 13 4.6 12.1 1.2 1 0 0 1 1 1 0 Xrn1 helical domain LptF_LptG PF03739.14 CDJ48670.1 - 0.038 12.9 2.1 0.2 10.5 0.1 2.6 2 1 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG MecA PF05389.12 CDJ48671.1 - 0.0022 17.7 3.6 0.0028 17.3 3.6 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) Spt20 PF12090.8 CDJ48671.1 - 0.0074 15.9 19.4 0.009 15.7 19.4 1.1 1 0 0 1 1 1 1 Spt20 family Spem1 PF15670.5 CDJ48671.1 - 0.23 11.0 5.2 0.28 10.7 5.2 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 eIF-3_zeta PF05091.12 CDJ48671.1 - 0.29 10.0 6.6 0.34 9.9 6.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ48671.1 - 0.3 12.1 6.9 0.43 11.6 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) VIR_N PF15912.5 CDJ48671.1 - 0.32 10.6 5.6 0.39 10.3 5.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal MAP65_ASE1 PF03999.12 CDJ48671.1 - 0.46 9.1 8.4 0.56 8.8 8.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RLL PF10036.9 CDJ48671.1 - 0.53 10.1 10.7 0.66 9.8 10.7 1.1 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein RR_TM4-6 PF06459.12 CDJ48671.1 - 0.69 9.7 6.2 0.71 9.6 6.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 CDJ48671.1 - 0.72 9.6 2.2 0.87 9.3 2.2 1.1 1 0 0 1 1 1 0 Connexin DUF1980 PF09323.10 CDJ48671.1 - 0.9 9.4 3.2 1.1 9.2 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Peptidase_S49_N PF08496.10 CDJ48671.1 - 0.93 9.5 6.6 1.3 9.1 6.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 CDJ48671.1 - 0.97 8.1 8.8 1 8.1 8.8 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ48671.1 - 1.1 7.1 4.0 1.1 7.0 4.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tim54 PF11711.8 CDJ48671.1 - 1.3 7.8 7.6 1.3 7.7 7.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hamartin PF04388.12 CDJ48671.1 - 1.4 7.5 9.4 1.8 7.1 9.4 1.2 1 0 0 1 1 1 0 Hamartin protein AAT PF03417.16 CDJ48671.1 - 1.5 8.4 7.4 2.6 7.7 7.3 1.5 1 1 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TERB2 PF15101.6 CDJ48671.1 - 1.6 8.8 9.7 2 8.4 9.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Lin-8 PF03353.15 CDJ48671.1 - 1.7 8.1 10.8 2 7.9 10.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 CDJ48671.1 - 1.7 5.7 11.3 1.7 5.7 11.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 CDJ48671.1 - 1.7 7.0 7.2 1.9 6.9 7.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 TMEM51 PF15345.6 CDJ48671.1 - 2 8.2 14.2 3.1 7.6 14.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Plasmodium_Vir PF05795.11 CDJ48671.1 - 2.6 7.4 5.2 2.8 7.3 5.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mif2_N PF15624.6 CDJ48671.1 - 3.3 8.4 12.1 4.7 7.9 12.1 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal PAT1 PF09770.9 CDJ48671.1 - 3.6 5.7 19.1 4 5.6 19.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ALMT PF11744.8 CDJ48671.1 - 4.3 6.1 5.1 4.6 6.0 5.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter EIIBC-GUT_N PF03612.14 CDJ48671.1 - 4.7 6.9 6.4 6.7 6.4 6.4 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Hid1 PF12722.7 CDJ48671.1 - 5.2 5.1 9.4 5.5 5.0 9.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pex14_N PF04695.13 CDJ48671.1 - 7.5 7.2 33.6 0.067 13.9 21.9 2.0 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5421 PF17458.2 CDJ48671.1 - 9.4 5.5 13.6 16 4.8 13.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) DUF5558 PF17713.1 CDJ48672.1 - 0.045 14.1 6.7 0.099 13.0 6.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5558) Hamartin PF04388.12 CDJ48672.1 - 0.18 10.5 34.4 0.24 10.0 34.4 1.3 1 0 0 1 1 1 0 Hamartin protein SR-25 PF10500.9 CDJ48673.1 - 0.94 9.0 30.9 0.047 13.3 23.3 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ48674.1 - 0.022 15.0 20.7 0.022 15.0 20.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Spt20 PF12090.8 CDJ48674.1 - 0.4 10.2 55.7 0.26 10.9 19.0 2.1 2 0 0 2 2 2 0 Spt20 family ASFV_J13L PF05568.11 CDJ48676.1 - 0.36 10.5 6.2 0.73 9.6 6.2 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein RskA PF10099.9 CDJ48676.1 - 4.4 7.6 18.7 0.15 12.3 12.0 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA UQ_con PF00179.26 CDJ48677.1 - 7.7e-12 45.0 0.0 1.4e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ48677.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain Reticulon PF02453.17 CDJ48678.1 - 8.5e-12 45.3 7.1 1.1e-11 45.0 6.5 1.4 1 1 0 1 1 1 1 Reticulon SNF2_N PF00176.23 CDJ48679.1 - 7.8e-48 163.0 0.0 4e-24 85.0 0.0 3.8 3 1 0 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ48679.1 - 2.9e-17 63.0 0.1 1.3e-16 60.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 CDJ48679.1 - 2.7e-06 27.6 0.8 2.7e-06 27.6 0.8 2.5 3 0 0 3 3 1 1 Ring finger domain zf-PARP PF00645.18 CDJ48679.1 - 1.5e-05 25.7 0.0 5.4e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-rbx1 PF12678.7 CDJ48679.1 - 3.2e-05 24.1 0.9 0.00012 22.2 0.7 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDJ48679.1 - 9.4e-05 22.4 0.7 0.00034 20.6 0.7 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ48679.1 - 0.00013 21.8 1.3 0.00013 21.8 1.3 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CDJ48679.1 - 0.00042 20.1 0.0 0.034 13.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_11 PF17123.5 CDJ48679.1 - 0.0022 17.7 3.9 0.0034 17.1 2.3 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDJ48679.1 - 0.0024 17.7 1.1 0.0024 17.7 1.1 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ48679.1 - 0.0036 17.3 0.2 0.01 15.9 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PyrI_C PF02748.15 CDJ48679.1 - 0.092 12.7 0.3 0.21 11.5 0.3 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ERCC3_RAD25_C PF16203.5 CDJ48679.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Eapp_C PF10238.9 CDJ48679.1 - 0.23 11.5 0.0 0.23 11.5 0.0 7.0 8 2 0 8 8 6 0 E2F-associated phosphoprotein UQ_con PF00179.26 CDJ48680.1 - 6.2e-45 152.3 0.0 8e-45 151.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ48680.1 - 0.22 11.8 1.3 0.44 10.9 1.0 1.6 1 1 0 1 1 1 0 RWD domain DUF4672 PF15716.5 CDJ48681.1 - 0.22 11.1 2.4 0.47 10.0 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) GLTP PF08718.11 CDJ48682.1 - 1.8e-23 83.5 0.0 2.4e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Ctr PF04145.15 CDJ48683.1 - 3.8e-16 60.0 15.8 4.3e-14 53.4 15.8 2.1 1 1 0 1 1 1 1 Ctr copper transporter family LapA_dom PF06305.11 CDJ48683.1 - 1 9.2 4.2 5.7 6.8 0.2 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4131 PF13567.6 CDJ48683.1 - 4.3 6.9 5.0 0.5 10.0 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Tail_spike_N PF18668.1 CDJ48684.1 - 0.11 12.3 0.2 0.11 12.3 0.2 1.8 2 0 0 2 2 2 0 Tail spike TSP1/Gp66 receptor binding N-terminal domain RRM_1 PF00076.22 CDJ48685.1 - 4.6e-15 55.2 0.0 7.3e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDJ48685.1 - 0.086 12.9 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 Limkain b1 FtsX PF02687.21 CDJ48686.1 - 1 9.9 7.3 1.5 9.3 7.3 1.3 1 0 0 1 1 1 0 FtsX-like permease family BRCT_3 PF18428.1 CDJ48688.1 - 0.17 11.9 0.1 0.4 10.8 0.1 1.6 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain FAM76 PF16046.5 CDJ48689.1 - 0.00051 19.5 25.5 0.00051 19.5 25.5 2.3 2 1 0 2 2 1 1 FAM76 protein CCSAP PF15748.5 CDJ48689.1 - 0.06 13.5 34.5 0.52 10.4 21.0 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated TCP PF03634.13 CDJ48689.1 - 0.076 13.6 35.4 0.86 10.1 20.3 2.1 2 0 0 2 2 2 0 TCP family transcription factor RB_B PF01857.20 CDJ48689.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.4 2 0 0 2 2 1 0 Retinoblastoma-associated protein B domain SLC12 PF03522.15 CDJ48689.1 - 0.24 10.4 26.9 0.94 8.4 19.6 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Presenilin PF01080.17 CDJ48689.1 - 0.26 10.0 34.8 0.34 9.6 22.2 2.1 2 0 0 2 2 2 0 Presenilin MID_MedPIWI PF18296.1 CDJ48689.1 - 0.33 10.7 38.6 0.069 12.9 5.4 2.1 2 0 0 2 2 2 0 MID domain of medPIWI PIP5K PF01504.18 CDJ48689.1 - 0.64 9.2 29.3 0.85 8.8 1.9 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Connexin PF00029.19 CDJ48689.1 - 0.74 9.5 22.8 9.9 5.8 0.1 2.2 2 0 0 2 2 2 0 Connexin DcuA_DcuB PF03605.14 CDJ48689.1 - 0.94 8.3 7.5 0.26 10.2 3.3 1.9 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter TFB6 PF17110.5 CDJ48689.1 - 1 9.1 12.7 4 7.2 9.9 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Serinc PF03348.15 CDJ48689.1 - 1.2 8.0 25.0 0.52 9.2 14.5 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) CDC45 PF02724.14 CDJ48689.1 - 1.3 7.2 23.1 2.8 6.1 0.4 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF913 PF06025.12 CDJ48689.1 - 1.5 7.7 25.3 1.3 8.0 2.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Usp PF00582.26 CDJ48689.1 - 1.9 9.0 7.0 3 8.4 4.4 2.1 2 0 0 2 2 2 0 Universal stress protein family RPN2_C PF18004.1 CDJ48689.1 - 2.3 8.1 23.3 1.1 9.1 16.7 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Rtf2 PF04641.12 CDJ48689.1 - 3 7.1 28.8 3.5 6.9 2.3 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger TRAP_alpha PF03896.16 CDJ48689.1 - 3.2 6.9 12.9 3.3 6.8 10.5 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit eIF-3_zeta PF05091.12 CDJ48689.1 - 3.7 6.4 35.8 2.7 6.9 28.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Striatin PF08232.12 CDJ48689.1 - 4.9 7.7 38.0 1 9.9 3.9 2.1 2 0 0 2 2 2 0 Striatin family CLN3 PF02487.17 CDJ48689.1 - 6.8 5.6 21.7 3.4 6.6 15.4 2.2 2 0 0 2 2 2 0 CLN3 protein CSG2 PF16965.5 CDJ48689.1 - 7.5 5.4 18.9 6 5.7 12.4 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator EOS1 PF12326.8 CDJ48689.1 - 9.7 6.1 20.0 12 5.8 0.8 2.3 2 0 0 2 2 2 0 N-glycosylation protein Spt20 PF12090.8 CDJ48690.1 - 1.4 8.5 13.3 0.019 14.6 6.5 1.4 2 0 0 2 2 2 0 Spt20 family FTZ PF03867.14 CDJ48690.1 - 4.3 6.8 7.3 4 6.9 5.9 1.6 1 1 1 2 2 2 0 Fushi tarazu (FTZ), N-terminal region DUF4834 PF16118.5 CDJ48691.1 - 5.1e-06 27.4 2.2 7.5e-06 26.8 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) LYRIC PF15686.5 CDJ48691.1 - 0.00013 21.7 2.9 0.00016 21.4 2.9 1.1 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family Conotoxin PF02950.17 CDJ48691.1 - 0.00016 22.6 1.7 0.00029 21.8 1.7 1.4 1 0 0 1 1 1 1 Conotoxin TMEM51 PF15345.6 CDJ48691.1 - 0.001 19.0 3.1 0.0012 18.7 3.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 eIF-3_zeta PF05091.12 CDJ48691.1 - 0.0019 17.3 1.7 0.0019 17.3 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ48691.1 - 0.0024 18.0 7.8 0.0024 18.0 7.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ48691.1 - 0.0025 18.1 6.1 0.0025 18.1 6.1 1.7 1 1 1 2 2 2 1 Anti-sigma-K factor rskA OPA3 PF07047.12 CDJ48691.1 - 0.0027 17.5 1.5 0.0042 16.9 1.5 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) FHIPEP PF00771.20 CDJ48691.1 - 0.0029 16.1 0.3 0.0038 15.8 0.3 1.1 1 0 0 1 1 1 1 FHIPEP family FAM176 PF14851.6 CDJ48691.1 - 0.0041 16.8 0.2 0.0056 16.3 0.2 1.2 1 0 0 1 1 1 1 FAM176 family V_ATPase_I PF01496.19 CDJ48691.1 - 0.011 13.7 2.3 0.013 13.4 2.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Suf PF05843.14 CDJ48691.1 - 0.012 15.6 2.1 0.012 15.6 2.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Connexin PF00029.19 CDJ48691.1 - 0.013 15.3 0.4 0.019 14.7 0.4 1.2 1 0 0 1 1 1 0 Connexin DUF1682 PF07946.14 CDJ48691.1 - 0.017 14.3 1.4 0.019 14.2 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Presenilin PF01080.17 CDJ48691.1 - 0.019 13.7 0.4 0.023 13.5 0.4 1.2 1 0 0 1 1 1 0 Presenilin DUF3402 PF11882.8 CDJ48691.1 - 0.026 13.7 3.7 0.033 13.3 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) XRN_N PF03159.18 CDJ48691.1 - 0.027 13.9 0.8 0.028 13.8 0.8 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DUF1980 PF09323.10 CDJ48691.1 - 0.062 13.2 0.1 0.07 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SID-1_RNA_chan PF13965.6 CDJ48691.1 - 0.068 11.6 0.0 0.087 11.2 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 OATP PF03137.20 CDJ48691.1 - 0.1 10.9 0.3 0.13 10.5 0.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CSG2 PF16965.5 CDJ48691.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF3357 PF11837.8 CDJ48691.1 - 0.13 12.7 2.9 0.18 12.3 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF2227 PF09988.9 CDJ48691.1 - 0.15 11.9 0.3 0.22 11.4 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) MTABC_N PF16185.5 CDJ48691.1 - 0.15 11.5 0.7 0.21 11.1 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region Tetraspanin PF00335.20 CDJ48691.1 - 0.16 11.6 0.8 0.21 11.3 0.8 1.1 1 0 0 1 1 1 0 Tetraspanin family Folate_carrier PF01770.18 CDJ48691.1 - 0.17 10.6 0.3 0.23 10.2 0.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF2973 PF11189.8 CDJ48691.1 - 0.21 11.7 2.7 0.54 10.4 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2973) DNApol_Exo PF18136.1 CDJ48691.1 - 0.21 10.7 5.6 0.3 10.2 5.6 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Scs3p PF10261.9 CDJ48691.1 - 0.24 10.9 0.6 0.33 10.4 0.6 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM CLN3 PF02487.17 CDJ48691.1 - 0.26 10.3 0.3 0.33 9.9 0.3 1.1 1 0 0 1 1 1 0 CLN3 protein Ctr PF04145.15 CDJ48691.1 - 0.31 11.6 4.2 0.7 10.5 4.4 1.4 1 1 1 2 2 2 0 Ctr copper transporter family HemY_N PF07219.13 CDJ48691.1 - 0.55 10.5 10.1 1.5 9.0 10.1 1.7 1 1 0 1 1 1 0 HemY protein N-terminus SseC PF04888.12 CDJ48691.1 - 0.63 9.6 10.5 0.81 9.2 10.5 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family TMEM100 PF16311.5 CDJ48691.1 - 1.8 8.1 4.8 1 8.9 3.1 1.5 1 1 0 1 1 1 0 Transmembrane protein 100 DivIC PF04977.15 CDJ48691.1 - 2.7 7.8 14.4 2.6 7.9 13.4 1.5 2 0 0 2 2 1 0 Septum formation initiator Trp_oprn_chp PF09534.10 CDJ48691.1 - 3.9 7.2 7.1 12 5.6 7.0 1.8 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Phage_holin_2_4 PF16082.5 CDJ48691.1 - 7.7 6.3 8.3 20 5.0 8.3 1.8 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF3579 PF12112.8 CDJ48692.1 - 0.011 16.2 1.2 3.4 8.3 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3579) Serinc PF03348.15 CDJ48692.1 - 0.29 10.0 2.6 0.32 9.9 2.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SWI-SNF_Ssr4 PF08549.10 CDJ48692.1 - 2.6 6.6 25.0 2.8 6.5 25.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Zip PF02535.22 CDJ48692.1 - 2.6 7.2 4.5 4.5 6.4 4.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ETRAMP PF09716.10 CDJ48692.1 - 8.1 6.6 11.6 8.4 6.5 0.1 2.9 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FtsX PF02687.21 CDJ48693.1 - 0.0044 17.5 1.2 0.012 16.1 0.1 2.0 2 0 0 2 2 2 1 FtsX-like permease family RskA PF10099.9 CDJ48694.1 - 0.077 13.3 0.0 0.077 13.3 0.0 14.7 3 3 7 12 12 12 0 Anti-sigma-K factor rskA TMEM51 PF15345.6 CDJ48696.1 - 0.014 15.2 7.6 0.015 15.2 7.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2098 PF09871.9 CDJ48696.1 - 0.015 15.7 4.4 0.018 15.3 4.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) CobT PF06213.12 CDJ48696.1 - 0.036 13.4 10.9 0.041 13.3 10.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CLN3 PF02487.17 CDJ48696.1 - 0.041 12.9 2.7 0.042 12.9 2.7 1.0 1 0 0 1 1 1 0 CLN3 protein Orf78 PF06024.12 CDJ48696.1 - 0.045 14.0 3.8 0.059 13.7 3.8 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Presenilin PF01080.17 CDJ48696.1 - 0.047 12.5 6.4 0.044 12.5 6.4 1.0 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.14 CDJ48696.1 - 0.055 13.2 4.6 0.053 13.3 4.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FAM176 PF14851.6 CDJ48696.1 - 0.058 13.1 4.8 0.074 12.7 4.8 1.1 1 0 0 1 1 1 0 FAM176 family eIF-3_zeta PF05091.12 CDJ48696.1 - 0.17 10.8 9.7 0.18 10.8 9.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Activator_LAG-3 PF11498.8 CDJ48696.1 - 0.18 10.7 45.1 0.21 10.5 45.1 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FAM60A PF15396.6 CDJ48696.1 - 0.19 11.7 3.9 0.19 11.7 3.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF1980 PF09323.10 CDJ48696.1 - 0.28 11.1 3.6 0.28 11.1 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CSG2 PF16965.5 CDJ48696.1 - 0.32 9.9 3.5 0.33 9.8 3.5 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Connexin PF00029.19 CDJ48696.1 - 0.33 10.7 6.6 0.37 10.5 6.6 1.1 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 CDJ48696.1 - 0.38 9.6 3.2 0.41 9.5 3.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Herpes_LMP1 PF05297.11 CDJ48696.1 - 0.4 9.8 4.1 0.47 9.6 4.1 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4834 PF16118.5 CDJ48696.1 - 0.4 11.7 9.5 0.52 11.3 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Folate_carrier PF01770.18 CDJ48696.1 - 0.66 8.6 4.5 0.69 8.6 4.5 1.0 1 0 0 1 1 1 0 Reduced folate carrier V_ATPase_I PF01496.19 CDJ48696.1 - 0.77 7.6 11.4 0.9 7.4 11.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0542 PF15086.6 CDJ48696.1 - 0.79 9.7 4.5 3.6 7.6 4.5 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0542 MCU PF04678.13 CDJ48696.1 - 0.86 9.7 7.3 0.93 9.6 7.3 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Neur_chan_memb PF02932.16 CDJ48696.1 - 1.1 9.2 6.1 1.3 9.1 6.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MMR1 PF08505.10 CDJ48696.1 - 1.1 9.4 12.4 1.3 9.3 12.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FliP PF00813.20 CDJ48696.1 - 1.3 8.9 4.5 1.3 8.8 4.5 1.1 1 0 0 1 1 1 0 FliP family TFIIA PF03153.13 CDJ48696.1 - 1.7 8.6 31.3 2 8.3 31.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OATP PF03137.20 CDJ48696.1 - 1.9 6.7 5.1 2.2 6.5 5.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Suf PF05843.14 CDJ48696.1 - 2.8 7.8 12.6 3.1 7.7 12.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ALMT PF11744.8 CDJ48696.1 - 3.9 6.2 7.0 3.9 6.2 7.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Paramyxo_ncap PF00973.19 CDJ48696.1 - 4.1 6.2 7.2 4.4 6.1 7.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein WBP-1 PF11669.8 CDJ48696.1 - 6.1 7.5 8.4 10 6.8 8.4 1.4 1 1 0 1 1 1 0 WW domain-binding protein 1 AAA_lid_2 PF17863.1 CDJ48696.1 - 7 6.6 9.2 1.2 9.0 0.4 2.5 2 1 0 2 2 2 0 AAA lid domain DUF3464 PF11947.8 CDJ48696.1 - 7.5 6.3 12.1 11 5.8 12.1 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Zip PF02535.22 CDJ48696.1 - 9.9 5.3 7.5 12 5.0 7.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Spt20 PF12090.8 CDJ48698.1 - 0.00061 19.5 5.3 0.00061 19.5 5.3 4.2 4 0 0 4 4 4 3 Spt20 family RskA PF10099.9 CDJ48698.1 - 0.00074 19.9 64.5 0.0019 18.5 0.2 5.4 2 1 2 4 4 4 2 Anti-sigma-K factor rskA YL1 PF05764.13 CDJ48698.1 - 0.0026 17.9 23.3 0.098 12.8 3.4 3.4 3 0 0 3 3 3 2 YL1 nuclear protein 7tm_3 PF00003.22 CDJ48698.1 - 0.016 15.0 2.4 0.088 12.5 2.2 2.0 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Cupin_5 PF06172.11 CDJ48698.1 - 0.022 14.9 0.0 0.022 14.9 0.0 2.5 3 0 0 3 3 3 0 Cupin superfamily (DUF985) SPX PF03105.19 CDJ48698.1 - 0.15 12.0 33.5 1.1 9.0 13.7 2.4 2 1 0 2 2 2 0 SPX domain IPP-2 PF04979.14 CDJ48698.1 - 0.48 11.1 21.9 1.2 9.9 0.0 3.8 4 0 0 4 4 4 0 Protein phosphatase inhibitor 2 (IPP-2) DUF2126 PF09899.9 CDJ48698.1 - 1.8 6.6 8.1 0.37 8.8 4.0 1.8 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) BUD22 PF09073.10 CDJ48698.1 - 3 7.1 31.7 0.033 13.5 6.4 3.0 3 0 0 3 3 3 0 BUD22 Kelch_3 PF13415.6 CDJ48700.1 - 0.002 18.4 7.6 0.81 10.0 0.0 4.6 3 0 0 3 3 3 2 Galactose oxidase, central domain RskA PF10099.9 CDJ48700.1 - 0.0059 16.9 0.9 0.0059 16.9 0.9 18.3 9 5 5 14 14 14 4 Anti-sigma-K factor rskA K_channel_TID PF07941.11 CDJ48702.1 - 0.018 15.4 9.3 0.018 15.4 9.3 7.6 5 3 1 6 6 6 0 Potassium channel Kv1.4 tandem inactivation domain Presenilin PF01080.17 CDJ48703.1 - 7.6e-05 21.6 13.7 7.6e-05 21.6 13.7 6.6 3 1 3 6 6 6 2 Presenilin Spt20 PF12090.8 CDJ48703.1 - 0.0003 20.5 28.2 0.0023 17.6 20.4 11.3 6 2 3 10 10 10 3 Spt20 family SAPS PF04499.15 CDJ48703.1 - 0.0029 16.5 7.4 0.0029 16.5 7.4 5.1 3 1 1 4 4 4 1 SIT4 phosphatase-associated protein DUF2722 PF10846.8 CDJ48703.1 - 0.023 13.7 0.3 0.023 13.7 0.3 12.8 6 3 3 11 11 11 0 Protein of unknown function (DUF2722) MelC1 PF06236.11 CDJ48704.1 - 0.015 15.4 3.8 0.023 14.8 3.8 1.2 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 DMSP_lyase PF16867.5 CDJ48704.1 - 2.2 7.9 13.0 4.9 6.8 4.8 2.5 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase MMR_HSR1 PF01926.23 CDJ48705.1 - 0.019 15.0 0.0 0.019 15.0 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase Myc_N PF01056.18 CDJ48706.1 - 0.33 10.8 10.9 0.35 10.7 10.9 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Glucan_synthase PF02364.15 CDJ48706.1 - 0.43 8.7 9.4 0.46 8.6 9.4 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Pinin_SDK_memA PF04696.13 CDJ48706.1 - 0.54 10.3 28.6 0.72 9.9 28.6 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region BSP_II PF05432.11 CDJ48706.1 - 0.79 9.4 10.3 0.9 9.2 10.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Spt20 PF12090.8 CDJ48706.1 - 1.4 8.5 25.2 1.9 8.0 25.2 1.2 1 0 0 1 1 1 0 Spt20 family Z1 PF10593.9 CDJ48706.1 - 1.9 7.9 12.8 1.9 7.9 12.8 1.0 1 0 0 1 1 1 0 Z1 domain DUF4746 PF15928.5 CDJ48706.1 - 2.1 7.7 16.1 2.3 7.5 16.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3381 PF11861.8 CDJ48706.1 - 2.5 7.9 22.8 3.3 7.5 22.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) SR-25 PF10500.9 CDJ48707.1 - 0.0097 15.5 22.8 0.011 15.4 13.2 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 CDJ48707.1 - 0.013 15.3 9.9 0.013 15.3 9.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Spt20 PF12090.8 CDJ48707.1 - 0.47 10.0 59.7 0.21 11.2 32.5 3.1 3 0 0 3 3 3 0 Spt20 family Nha1_C PF08619.10 CDJ48707.1 - 0.96 8.6 23.4 1 8.5 3.9 2.2 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Band_3_cyto PF07565.13 CDJ48707.1 - 2.9 7.6 15.8 3.3 7.4 1.6 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Sec62 PF03839.16 CDJ48707.1 - 3.2 7.2 4.4 1.1 8.8 0.4 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 DUF2052 PF09747.9 CDJ48707.1 - 4.6 7.3 14.7 8.1 6.5 8.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Hamartin PF04388.12 CDJ48707.1 - 6.7 5.3 26.0 11 4.6 26.0 1.3 1 0 0 1 1 1 0 Hamartin protein Rxt3 PF08642.10 CDJ48707.1 - 7.5 7.3 9.3 0.42 11.4 0.3 2.7 2 1 0 2 2 2 0 Histone deacetylation protein Rxt3 FAM60A PF15396.6 CDJ48707.1 - 7.6 6.5 12.0 1.9 8.5 1.9 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF4614 PF15391.6 CDJ48707.1 - 8.7 6.3 26.2 9 6.2 11.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DUF4179 PF13786.6 CDJ48708.1 - 0.14 12.7 0.5 0.14 12.7 0.5 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) Asp PF00026.23 CDJ48709.1 - 4.9e-42 144.5 0.0 4.4e-40 138.0 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ48709.1 - 1.5e-05 25.3 0.1 1.5e-05 25.3 0.1 4.1 3 2 1 4 4 4 2 Xylanase inhibitor N-terminal SET PF00856.28 CDJ48710.1 - 0.033 14.6 0.0 0.081 13.3 0.0 1.7 1 1 0 1 1 1 0 SET domain TRAPPC-Trs85 PF12739.7 CDJ48711.1 - 2.2e-43 148.8 42.0 2.2e-43 148.8 42.0 7.8 3 3 1 4 4 4 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SR-25 PF10500.9 CDJ48711.1 - 0.00024 20.8 10.5 0.00024 20.8 10.5 12.0 11 2 0 12 12 12 4 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ48711.1 - 0.0024 18.2 14.5 0.0024 18.2 14.5 15.9 8 6 4 13 13 13 4 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ48711.1 - 0.0044 17.6 4.0 0.0044 17.6 4.0 17.3 13 3 2 15 15 15 4 60s Acidic ribosomal protein DDHD PF02862.17 CDJ48711.1 - 0.0077 16.4 4.0 0.0077 16.4 4.0 9.4 3 2 0 3 3 3 1 DDHD domain Cellulose_synt PF03552.14 CDJ48711.1 - 2.1 6.8 3.0 7 5.0 3.0 1.9 1 0 0 1 1 1 0 Cellulose synthase SR-25 PF10500.9 CDJ48712.1 - 2.9e-06 27.1 15.6 2.9e-06 27.1 15.6 2.9 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ48712.1 - 1.7 7.3 33.5 0.64 8.7 5.5 2.3 2 0 0 2 2 2 0 Presenilin Spt20 PF12090.8 CDJ48712.1 - 3.8 7.0 49.7 1.8 8.1 12.4 2.5 2 0 0 2 2 2 0 Spt20 family TAF1D PF15333.6 CDJ48712.1 - 5.9 6.6 13.2 0.58 9.9 7.8 1.9 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D Endostatin PF06482.11 CDJ48712.1 - 7.8 5.9 23.7 1.9 7.9 12.2 2.6 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Utp14 PF04615.13 CDJ48713.1 - 0.00025 19.8 7.2 0.00025 19.8 7.2 2.1 1 1 1 2 2 2 1 Utp14 protein RskA PF10099.9 CDJ48713.1 - 0.0023 18.3 22.2 0.0023 18.3 22.2 5.6 1 1 3 4 4 4 2 Anti-sigma-K factor rskA Peroxin-13_N PF04088.13 CDJ48713.1 - 0.017 15.4 0.4 0.017 15.4 0.4 5.7 4 1 1 5 5 5 0 Peroxin 13, N-terminal region SARAF PF06682.12 CDJ48713.1 - 0.055 13.1 0.0 0.055 13.1 0.0 4.2 1 1 3 4 4 4 0 SOCE-associated regulatory factor of calcium homoeostasis Hamartin PF04388.12 CDJ48713.1 - 0.17 10.5 43.5 0.056 12.1 39.3 1.9 2 0 0 2 2 2 0 Hamartin protein DUF3446 PF11928.8 CDJ48713.1 - 2.2 8.7 8.9 2.4 8.5 1.0 3.0 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ48714.1 - 0.00014 21.5 26.5 0.00021 21.0 26.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF1645 PF07816.11 CDJ48714.1 - 0.00059 20.5 7.3 0.00067 20.3 7.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) DUF755 PF05501.11 CDJ48714.1 - 0.00073 19.8 35.8 0.0013 18.9 35.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF755) AF-4 PF05110.13 CDJ48714.1 - 0.00076 17.7 24.2 0.00092 17.4 24.2 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein DUF4692 PF15763.5 CDJ48714.1 - 0.021 15.3 12.8 0.028 14.9 12.8 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) GREB1 PF15782.5 CDJ48714.1 - 0.027 11.6 17.5 0.028 11.6 17.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CDJ48714.1 - 0.045 13.2 6.2 0.045 13.2 6.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.12 CDJ48714.1 - 0.064 12.2 8.2 0.067 12.2 8.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Herpes_pp85 PF04637.12 CDJ48714.1 - 0.065 11.7 5.3 0.074 11.5 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Macoilin PF09726.9 CDJ48714.1 - 0.069 11.7 14.3 0.073 11.6 14.3 1.0 1 0 0 1 1 1 0 Macoilin family DUF4746 PF15928.5 CDJ48714.1 - 0.099 12.0 4.7 0.11 11.9 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Tudor_3 PF18115.1 CDJ48714.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Mem_trans PF03547.18 CDJ48714.1 - 0.18 10.2 5.3 0.2 10.0 5.3 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF2052 PF09747.9 CDJ48714.1 - 0.22 11.6 11.3 0.29 11.3 11.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Lin-8 PF03353.15 CDJ48714.1 - 0.25 10.9 22.6 0.31 10.6 22.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF572 PF04502.13 CDJ48714.1 - 0.33 10.5 10.4 0.38 10.3 10.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Band_3_cyto PF07565.13 CDJ48714.1 - 0.4 10.4 11.6 0.42 10.4 11.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CPSF100_C PF13299.6 CDJ48714.1 - 0.4 10.8 6.0 0.54 10.4 6.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SPX PF03105.19 CDJ48714.1 - 0.49 10.3 22.0 0.62 9.9 22.0 1.0 1 0 0 1 1 1 0 SPX domain NicO PF03824.16 CDJ48714.1 - 0.51 9.6 2.2 0.55 9.5 2.2 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Peroxin-3 PF04882.12 CDJ48714.1 - 0.54 9.2 18.4 0.71 8.8 18.4 1.1 1 0 0 1 1 1 0 Peroxin-3 DUF1387 PF07139.11 CDJ48714.1 - 0.73 9.5 17.7 0.83 9.3 17.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TFIIA PF03153.13 CDJ48714.1 - 0.85 9.5 33.0 1 9.3 33.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ48714.1 - 0.87 9.3 4.2 1 9.1 4.2 1.3 1 0 0 1 1 1 0 Connexin DUF4175 PF13779.6 CDJ48714.1 - 1 7.2 23.7 1.1 7.1 23.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SOG2 PF10428.9 CDJ48714.1 - 1.3 8.2 20.6 1.5 7.9 20.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RR_TM4-6 PF06459.12 CDJ48714.1 - 1.3 8.8 8.5 1.5 8.5 8.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Miga PF10265.9 CDJ48714.1 - 1.5 7.7 13.3 1.6 7.6 13.3 1.0 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 CDJ48714.1 - 1.6 7.5 16.5 1.9 7.3 16.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ48714.1 - 1.6 7.4 18.3 1.9 7.1 18.3 1.0 1 0 0 1 1 1 0 Presenilin DUF2126 PF09899.9 CDJ48714.1 - 2.1 6.3 8.5 2.5 6.1 8.5 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Kinesin_assoc PF16183.5 CDJ48714.1 - 2.1 8.5 4.1 2.8 8.0 4.1 1.3 1 0 0 1 1 1 0 Kinesin-associated PAP1 PF08601.10 CDJ48714.1 - 2.4 7.8 21.9 3.2 7.4 21.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 CLN3 PF02487.17 CDJ48714.1 - 3.3 6.7 9.1 3.8 6.5 9.1 1.1 1 0 0 1 1 1 0 CLN3 protein MPM1 PF17234.2 CDJ48714.1 - 3.5 7.9 15.8 3.2 8.0 14.5 1.5 2 0 0 2 2 1 0 Mitochondrial peculiar membrane protein 1 SLC12 PF03522.15 CDJ48714.1 - 4 6.3 14.3 4.8 6.1 14.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Paf1 PF03985.13 CDJ48714.1 - 4.1 6.3 16.2 5.5 5.9 16.2 1.1 1 0 0 1 1 1 0 Paf1 ALMT PF11744.8 CDJ48714.1 - 5.3 5.8 13.3 6.2 5.5 13.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1180 PF06679.12 CDJ48714.1 - 5.6 7.3 11.7 7.3 7.0 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) V_ATPase_I PF01496.19 CDJ48714.1 - 8.5 4.1 13.5 9.9 3.9 13.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC53 PF10152.9 CDJ48714.1 - 8.6 6.8 14.0 13 6.2 14.0 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PAT1 PF09770.9 CDJ48714.1 - 8.7 4.5 24.6 10 4.2 24.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Membralin PF09746.9 CDJ48714.1 - 9.1 5.2 8.5 11 5.0 8.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein SelP_N PF04592.14 CDJ48714.1 - 9.4 5.6 24.1 14 5.0 24.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SR-25 PF10500.9 CDJ48715.1 - 0.0028 17.3 3.1 0.0028 17.3 3.1 4.4 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein DUF1664 PF07889.12 CDJ48715.1 - 0.12 12.4 18.3 0.78 9.8 10.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BAF1_ABF1 PF04684.13 CDJ48716.1 - 0.0015 17.7 8.3 0.0017 17.5 8.3 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.9 CDJ48716.1 - 0.003 17.2 6.0 0.003 17.2 6.0 2.0 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Auxin_canalis PF05703.11 CDJ48716.1 - 0.0036 17.3 15.9 0.0044 17.0 15.9 1.1 1 0 0 1 1 1 1 Auxin canalisation Enolase_N PF03952.16 CDJ48716.1 - 0.013 15.7 3.2 0.022 14.9 3.2 1.5 1 0 0 1 1 1 0 Enolase, N-terminal domain Activator_LAG-3 PF11498.8 CDJ48716.1 - 0.013 14.5 62.6 0.016 14.2 62.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SUR7 PF06687.12 CDJ48716.1 - 0.013 15.1 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 SUR7/PalI family FAM222A PF15258.6 CDJ48716.1 - 0.069 12.2 28.9 0.098 11.7 28.9 1.2 1 0 0 1 1 1 0 Protein family of FAM222A MRP-S31 PF15433.6 CDJ48716.1 - 0.084 12.5 16.1 0.11 12.2 16.1 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 CCSAP PF15748.5 CDJ48716.1 - 0.16 12.1 16.0 0.21 11.7 16.0 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated V_ATPase_I PF01496.19 CDJ48716.1 - 0.19 9.6 10.1 0.22 9.4 10.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EphA2_TM PF14575.6 CDJ48716.1 - 0.25 12.3 0.4 0.25 12.3 0.4 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4179 PF13786.6 CDJ48716.1 - 0.3 11.6 8.4 0.12 12.8 5.9 1.6 1 1 1 2 2 1 0 Domain of unknown function (DUF4179) CDC24_OB1 PF17246.2 CDJ48716.1 - 0.32 11.1 5.0 5 7.3 1.1 2.2 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 1 Hexokinase_2 PF03727.16 CDJ48716.1 - 0.36 10.2 5.6 0.46 9.9 5.6 1.1 1 0 0 1 1 1 0 Hexokinase Hydant_A_N PF05378.13 CDJ48716.1 - 0.57 9.9 6.2 0.48 10.1 4.9 1.4 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Peptidase_M56 PF05569.11 CDJ48716.1 - 0.72 9.0 9.5 1 8.5 9.5 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ribosomal_60s PF00428.19 CDJ48716.1 - 0.86 10.2 9.8 1.5 9.5 9.8 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein INSIG PF07281.12 CDJ48716.1 - 1.1 8.8 5.5 2.9 7.5 5.4 1.7 1 1 0 1 1 1 0 Insulin-induced protein (INSIG) UPF0565 PF10561.9 CDJ48716.1 - 1.2 8.2 8.0 1.6 7.9 8.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PAT1 PF09770.9 CDJ48716.1 - 1.2 7.3 29.1 1.3 7.2 29.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOBP PF15279.6 CDJ48716.1 - 1.8 9.1 16.3 2 9.0 16.3 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2722 PF10846.8 CDJ48716.1 - 2.1 7.2 31.5 0.081 11.9 6.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Salt_tol_Pase PF09506.10 CDJ48716.1 - 2.6 6.7 16.9 3.1 6.5 16.9 1.0 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Med15 PF09606.10 CDJ48716.1 - 2.6 6.6 47.8 3.4 6.2 47.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Trp_oprn_chp PF09534.10 CDJ48716.1 - 2.6 7.8 17.1 4.5 7.0 17.1 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Nicastrin PF05450.15 CDJ48716.1 - 2.8 7.3 14.4 0.047 13.1 3.9 2.1 1 1 1 2 2 2 0 Nicastrin Presenilin PF01080.17 CDJ48716.1 - 2.8 6.6 12.7 3.6 6.2 12.7 1.1 1 0 0 1 1 1 0 Presenilin Draxin PF15550.6 CDJ48716.1 - 3.3 7.5 12.2 4.1 7.2 12.2 1.1 1 0 0 1 1 1 0 Draxin Peptidase_S46 PF10459.9 CDJ48716.1 - 3.9 6.0 15.4 4.7 5.7 15.4 1.0 1 0 0 1 1 1 0 Peptidase S46 RRT14 PF17075.5 CDJ48716.1 - 4.6 7.3 16.7 1.6 8.9 2.1 2.1 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 DUF5470 PF17564.2 CDJ48716.1 - 4.7 7.5 5.4 0.52 10.5 1.0 1.7 2 0 0 2 2 1 0 Family of unknown function (DUF5470) SYF2 PF08231.12 CDJ48716.1 - 5.1 7.5 10.4 7.2 7.0 10.4 1.1 1 0 0 1 1 1 0 SYF2 splicing factor MRPL52 PF18699.1 CDJ48716.1 - 6 7.1 22.6 0.48 10.7 3.4 2.1 2 0 0 2 2 2 0 Mitoribosomal protein mL52 DUF3357 PF11837.8 CDJ48716.1 - 6.3 7.3 11.6 3 8.3 8.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Sarcoglycan_2 PF05510.13 CDJ48716.1 - 7.1 5.3 13.5 11 4.7 2.6 1.5 1 1 1 2 2 2 0 Sarcoglycan alpha/epsilon SR-25 PF10500.9 CDJ48717.1 - 9.3e-05 22.1 93.6 0.00075 19.2 39.1 4.2 3 1 1 4 4 4 3 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ48719.1 - 0.00019 21.1 29.5 0.002 17.8 8.6 5.9 5 2 1 6 6 6 4 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ48719.1 - 0.00034 21.0 14.0 0.00034 21.0 14.0 6.0 1 1 2 4 4 4 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ48720.1 - 0.004 17.2 12.2 0.0053 16.8 12.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 CDJ48720.1 - 0.065 12.9 5.5 0.087 12.5 5.5 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis BCS1_N PF08740.11 CDJ48720.1 - 0.066 13.2 0.1 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 BCS1 N terminal RCR PF12273.8 CDJ48720.1 - 0.4 11.3 8.7 0.65 10.7 1.6 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red SRP-alpha_N PF04086.13 CDJ48720.1 - 0.46 10.4 5.2 0.59 10.0 5.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Dehydrin PF00257.19 CDJ48720.1 - 0.75 10.3 12.6 0.37 11.3 6.5 2.2 2 0 0 2 2 2 0 Dehydrin DNA_ligase_A_M PF01068.21 CDJ48721.1 - 2.5e-08 33.8 0.0 2.5e-08 33.8 0.0 2.5 1 1 1 2 2 1 1 ATP dependent DNA ligase domain TFIIA PF03153.13 CDJ48721.1 - 0.0064 16.5 44.2 0.0077 16.3 44.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PNISR PF15996.5 CDJ48721.1 - 0.0073 16.6 18.3 0.0089 16.3 18.3 1.1 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR Presenilin PF01080.17 CDJ48721.1 - 0.0088 14.9 20.9 0.011 14.6 20.9 1.1 1 0 0 1 1 1 1 Presenilin DDHD PF02862.17 CDJ48721.1 - 0.025 14.7 10.8 0.037 14.2 10.8 1.3 1 0 0 1 1 1 0 DDHD domain Lin-8 PF03353.15 CDJ48721.1 - 0.028 14.0 21.5 0.032 13.8 21.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist eIF3_subunit PF08597.10 CDJ48721.1 - 0.039 13.9 14.5 0.046 13.6 14.5 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4638 PF15472.6 CDJ48721.1 - 0.042 13.6 10.1 0.047 13.4 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) PIEZO PF15917.5 CDJ48721.1 - 0.048 13.1 18.8 0.059 12.8 18.8 1.2 1 0 0 1 1 1 0 Piezo SRP-alpha_N PF04086.13 CDJ48721.1 - 0.055 13.4 16.1 0.067 13.1 16.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal V_ATPase_I PF01496.19 CDJ48721.1 - 0.055 11.4 13.0 0.065 11.2 13.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hydin_ADK PF17213.3 CDJ48721.1 - 0.061 13.6 10.5 0.081 13.2 10.5 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain NPR3 PF03666.13 CDJ48721.1 - 0.1 11.4 14.2 0.12 11.1 14.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 eIF-3_zeta PF05091.12 CDJ48721.1 - 0.11 11.5 21.5 0.13 11.2 21.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MCM_bind PF09739.9 CDJ48721.1 - 0.11 11.0 15.1 0.12 10.8 15.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Exonuc_VII_L PF02601.15 CDJ48721.1 - 0.12 11.9 16.8 0.15 11.6 16.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Otopetrin PF03189.13 CDJ48721.1 - 0.13 11.1 4.6 0.14 10.9 4.6 1.1 1 0 0 1 1 1 0 Otopetrin PTPRCAP PF15713.5 CDJ48721.1 - 0.13 12.6 18.9 0.2 11.9 18.9 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FAM60A PF15396.6 CDJ48721.1 - 0.13 12.2 12.3 0.16 11.9 12.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 CDJ48721.1 - 0.14 11.1 19.1 0.15 11.1 19.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Tim54 PF11711.8 CDJ48721.1 - 0.2 10.4 15.9 0.24 10.2 15.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PQQ PF01011.21 CDJ48721.1 - 0.21 11.6 0.0 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat Peptidase_S64 PF08192.11 CDJ48721.1 - 0.27 9.7 12.6 0.3 9.5 12.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 SpoVR PF04293.13 CDJ48721.1 - 0.32 9.6 14.1 0.43 9.2 14.1 1.1 1 0 0 1 1 1 0 SpoVR like protein CDC45 PF02724.14 CDJ48721.1 - 0.34 9.1 15.7 0.41 8.9 15.7 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ48721.1 - 0.37 10.6 22.1 0.48 10.2 22.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CDJ48721.1 - 0.4 7.8 17.6 0.45 7.6 17.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 CDJ48721.1 - 0.44 9.7 8.7 0.46 9.7 8.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Bul1_N PF04425.12 CDJ48721.1 - 0.72 8.5 14.6 0.88 8.3 14.6 1.1 1 0 0 1 1 1 0 Bul1 N terminus DUF913 PF06025.12 CDJ48721.1 - 0.81 8.6 10.1 1 8.2 10.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2052 PF09747.9 CDJ48721.1 - 0.86 9.7 22.3 1.1 9.3 22.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) ALMT PF11744.8 CDJ48721.1 - 1.5 7.5 15.1 2 7.2 15.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HGTP_anticodon2 PF12745.7 CDJ48721.1 - 1.6 8.1 16.4 2.3 7.7 16.4 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF2151 PF10221.9 CDJ48721.1 - 1.9 7.0 13.2 2.5 6.6 13.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator PAT1 PF09770.9 CDJ48721.1 - 2.2 6.4 38.3 2.8 6.1 38.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Membralin PF09746.9 CDJ48721.1 - 3.4 6.6 11.3 4.3 6.3 11.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein Dicty_REP PF05086.12 CDJ48721.1 - 3.8 5.4 11.6 4.2 5.2 11.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.10 CDJ48721.1 - 4 6.0 17.4 4.4 5.9 17.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 CDJ48721.1 - 4 7.4 16.8 5.3 7.0 16.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 CDJ48721.1 - 4.9 5.2 21.6 6.2 4.8 21.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Endostatin PF06482.11 CDJ48721.1 - 4.9 6.5 20.0 7.2 6.0 20.0 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF2828 PF11443.8 CDJ48721.1 - 6.6 4.7 18.5 8.6 4.3 18.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Lipase_GDSL_2 PF13472.6 CDJ48722.1 - 5.4 7.4 14.9 0.055 13.9 2.3 2.6 2 1 1 3 3 3 0 GDSL-like Lipase/Acylhydrolase family FAM60A PF15396.6 CDJ48722.1 - 7.2 6.5 17.5 5.8 6.9 9.5 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Lin-8 PF03353.15 CDJ48722.1 - 7.5 6.0 27.2 0.031 13.8 10.6 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.13 CDJ48722.1 - 7.9 6.2 17.8 5.5 6.7 9.3 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Peptidase_S64 PF08192.11 CDJ48722.1 - 8.9 4.7 14.4 0.31 9.5 6.2 2.0 2 0 0 2 2 2 0 Peptidase family S64 MAT1 PF06391.13 CDJ48722.1 - 9 6.1 37.2 0.087 12.6 18.7 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 SLC12 PF03522.15 CDJ48722.1 - 9.4 5.1 20.1 7.9 5.4 13.1 2.1 2 0 0 2 2 2 0 Solute carrier family 12 DNA_ligase_IV PF11411.8 CDJ48723.1 - 2.9e-06 27.3 0.2 5.5e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 DNA ligase IV Spt20 PF12090.8 CDJ48723.1 - 0.00047 19.8 8.3 0.00047 19.8 8.3 5.0 3 2 2 5 5 5 1 Spt20 family Presenilin PF01080.17 CDJ48723.1 - 0.0007 18.5 13.0 0.0007 18.5 13.0 3.7 2 1 0 2 2 2 1 Presenilin DUF2722 PF10846.8 CDJ48723.1 - 0.0047 15.9 6.3 0.0047 15.9 6.3 4.6 3 1 1 4 4 4 2 Protein of unknown function (DUF2722) BRCT_2 PF16589.5 CDJ48723.1 - 0.11 12.9 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Apolipoprotein PF01442.18 CDJ48725.1 - 0.0065 16.4 6.4 0.0088 15.9 6.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 CDJ48725.1 - 0.009 16.1 2.2 0.009 16.1 2.2 4.2 3 1 1 4 4 4 2 Late embryogenesis abundant protein RebB PF11747.8 CDJ48725.1 - 0.014 15.5 0.4 0.014 15.5 0.4 2.1 2 0 0 2 2 2 0 Killing trait YtxH PF12732.7 CDJ48725.1 - 0.022 15.3 2.0 0.022 15.3 2.0 3.0 1 1 1 2 2 2 0 YtxH-like protein DUF883 PF05957.13 CDJ48725.1 - 0.033 14.8 17.3 0.86 10.2 0.7 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) LEA_1 PF03760.15 CDJ48725.1 - 0.037 14.7 38.1 0.78 10.4 4.4 2.6 2 1 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 MatP_C PF17414.2 CDJ48725.1 - 0.045 13.9 0.3 0.63 10.3 0.2 2.5 1 1 1 2 2 2 0 MatP C-terminal ribbon-helix-helix domain GvpL_GvpF PF06386.11 CDJ48725.1 - 0.92 9.4 7.2 0.22 11.4 3.0 1.7 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF AD PF09793.9 CDJ48725.1 - 1.6 8.9 4.0 1.6 8.9 0.2 2.5 1 1 2 3 3 3 0 Anticodon-binding domain Mitofilin PF09731.9 CDJ48725.1 - 4.1 6.1 20.2 4.7 5.9 20.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CAP160 PF07918.11 CDJ48725.1 - 8.5 6.2 11.6 1.3 8.8 3.0 3.2 3 0 0 3 3 3 0 CAP160 repeat DUF4207 PF13904.6 CDJ48726.1 - 0.00014 21.7 3.0 0.00014 21.7 3.0 6.9 5 1 0 5 5 5 1 Domain of unknown function (DUF4207) Spt20 PF12090.8 CDJ48726.1 - 0.0015 18.2 0.6 0.0015 18.2 0.6 7.1 5 2 1 6 6 6 3 Spt20 family DUF2722 PF10846.8 CDJ48726.1 - 0.0052 15.8 0.6 0.0052 15.8 0.6 7.0 7 0 0 7 7 7 3 Protein of unknown function (DUF2722) TFIIIC_sub6 PF10419.9 CDJ48727.1 - 0.16 11.9 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 TFIIIC subunit triple barrel domain TFIIA PF03153.13 CDJ48727.1 - 5.4 6.9 14.3 7.9 6.4 14.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Adipogenin PF15202.6 CDJ48728.1 - 1.5 8.9 4.2 1.3 9.1 1.4 2.2 1 1 1 2 2 2 0 Adipogenin AAA_19 PF13245.6 CDJ48729.1 - 0.07 13.5 0.3 0.18 12.1 0.3 1.6 1 0 0 1 1 1 0 AAA domain Wzy_C PF04932.15 CDJ48729.1 - 0.23 11.1 6.1 0.1 12.2 3.9 1.5 1 1 0 1 1 1 0 O-Antigen ligase ABC_tran PF00005.27 CDJ48730.1 - 9.3e-50 168.7 0.0 1.5e-26 93.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDJ48730.1 - 5.8e-24 84.8 26.4 3.4e-08 33.0 9.2 3.4 2 1 1 3 3 3 3 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ48730.1 - 1.2e-16 61.4 0.6 9.2e-08 32.2 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ48730.1 - 0.00017 21.2 2.7 0.087 12.6 0.2 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 CDJ48730.1 - 0.00073 19.0 0.1 4.9 6.5 0.0 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 CDJ48730.1 - 0.0058 17.3 0.0 6.8 7.5 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 CDJ48730.1 - 0.0061 16.5 1.5 0.03 14.2 0.1 2.4 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 CDJ48730.1 - 0.041 14.0 3.6 0.33 11.0 0.4 3.6 4 0 0 4 4 4 0 50S ribosome-binding GTPase AAA_23 PF13476.6 CDJ48730.1 - 0.053 14.0 0.2 0.053 14.0 0.2 2.7 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 CDJ48730.1 - 0.16 12.3 0.0 8.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CDJ48730.1 - 0.17 11.6 0.3 9.3 5.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CDJ48730.1 - 0.52 9.6 2.4 0.8 8.9 0.1 2.4 3 0 0 3 3 3 0 Zeta toxin DUF87 PF01935.17 CDJ48730.1 - 3.2 7.8 4.5 1 9.4 0.4 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain EF-hand_6 PF13405.6 CDJ48731.1 - 3.1e-07 29.8 0.1 1.1e-06 28.0 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CDJ48731.1 - 2.2e-06 26.8 0.5 4.1e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CDJ48731.1 - 6.4e-05 23.3 0.1 0.00019 21.8 0.1 1.8 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ48731.1 - 0.019 14.4 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_9 PF14658.6 CDJ48731.1 - 0.043 14.1 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain Adenine_glyco PF03352.13 CDJ48731.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 2 0 0 2 2 2 0 Methyladenine glycosylase DUF2828 PF11443.8 CDJ48734.1 - 0.32 9.0 6.1 0.46 8.5 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MDM10 PF12519.8 CDJ48734.1 - 0.55 9.0 10.6 0.81 8.5 10.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PAXNEB PF05625.11 CDJ48734.1 - 1.7 7.7 15.4 0.071 12.2 6.9 2.2 2 0 0 2 2 2 0 PAXNEB protein Presenilin PF01080.17 CDJ48734.1 - 1.9 7.1 15.9 3.6 6.3 15.9 1.3 1 0 0 1 1 1 0 Presenilin Rpp20 PF12328.8 CDJ48734.1 - 3.5 7.6 11.4 2.8 7.9 3.0 2.3 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P EIIBC-GUT_N PF03612.14 CDJ48734.1 - 8.7 6.0 11.1 5.2 6.8 3.9 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Spt5_N PF11942.8 CDJ48734.1 - 9.1 7.3 16.1 1.4 9.9 7.4 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF3464 PF11947.8 CDJ48734.1 - 9.5 6.0 13.3 18 5.1 0.7 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 EOS1 PF12326.8 CDJ48734.1 - 9.6 6.1 5.4 2e+02 1.8 6.2 2.0 1 1 0 1 1 1 0 N-glycosylation protein IMP2_N PF18590.1 CDJ48735.1 - 2e-26 92.4 1.2 3.1e-26 91.7 1.2 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain SOBP PF15279.6 CDJ48735.1 - 1.2 9.7 9.9 1.6 9.3 9.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RRM_1 PF00076.22 CDJ48736.1 - 6.3e-16 58.0 0.0 1.3e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 CDJ48736.1 - 7.7e-10 39.3 0.0 7.7e-10 39.3 0.0 2.0 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_60s PF00428.19 CDJ48736.1 - 0.00014 22.4 8.2 0.00014 22.4 8.2 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF908 PF06012.12 CDJ48736.1 - 0.14 11.5 3.4 0.25 10.7 3.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TFIIA PF03153.13 CDJ48736.1 - 1.5 8.8 30.4 0.22 11.5 26.6 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HEAT PF02985.22 CDJ48737.1 - 1.2e-05 25.1 1.2 0.0005 20.1 0.1 3.1 3 0 0 3 3 3 1 HEAT repeat TFIIA PF03153.13 CDJ48737.1 - 0.02 14.9 19.4 0.025 14.6 19.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Arm PF00514.23 CDJ48737.1 - 0.12 12.5 3.8 9.3 6.5 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat GREB1 PF15782.5 CDJ48737.1 - 0.14 9.3 7.1 0.14 9.2 7.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BORG_CEP PF14957.6 CDJ48737.1 - 0.34 12.1 11.8 0.61 11.3 11.8 1.3 1 0 0 1 1 1 0 Cdc42 effector DUF1635 PF07795.11 CDJ48737.1 - 0.45 10.4 13.9 0.89 9.4 13.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Spt20 PF12090.8 CDJ48737.1 - 0.57 9.7 19.6 0.75 9.4 18.3 1.8 2 0 0 2 2 2 0 Spt20 family Macoilin PF09726.9 CDJ48737.1 - 1.5 7.3 8.6 2.3 6.7 8.6 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ48737.1 - 1.7 7.4 8.9 2.5 6.8 8.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ48737.1 - 2.8 7.5 16.4 4.8 6.7 16.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DLIC PF05783.11 CDJ48737.1 - 3.8 6.2 7.1 5.9 5.6 7.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Lin-8 PF03353.15 CDJ48737.1 - 7.4 6.0 13.0 10 5.6 13.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SUIM_assoc PF16619.5 CDJ48737.1 - 9.2 6.4 24.2 1.8e+04 -6.5 24.1 2.9 1 1 0 1 1 0 0 Unstructured region C-term to UIM in Ataxin3 Utp21 PF04192.12 CDJ48738.1 - 1.1e-13 51.2 0.0 1.1e-13 51.2 0.0 3.7 4 1 0 4 4 4 1 Utp21 specific WD40 associated putative domain SR-25 PF10500.9 CDJ48738.1 - 0.00074 19.2 40.0 0.02 14.5 11.2 3.3 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ48738.1 - 0.093 11.7 0.0 0.093 11.7 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) DUF2207 PF09972.9 CDJ48738.1 - 0.2 10.4 0.6 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Connexin PF00029.19 CDJ48739.1 - 0.00035 20.4 2.9 0.00038 20.3 2.9 1.0 1 0 0 1 1 1 1 Connexin V_ATPase_I PF01496.19 CDJ48739.1 - 0.00045 18.3 8.7 0.00046 18.3 8.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4834 PF16118.5 CDJ48739.1 - 0.00085 20.2 4.2 0.001 20.0 4.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) TssO PF17561.2 CDJ48739.1 - 0.0024 18.0 3.0 0.0026 17.9 3.0 1.1 1 0 0 1 1 1 1 Type VI secretion system, TssO MSP1a PF11670.8 CDJ48739.1 - 0.011 15.0 1.0 0.013 14.9 1.0 1.0 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF2572 PF10833.8 CDJ48739.1 - 0.014 15.1 14.2 0.015 15.1 14.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Conotoxin PF02950.17 CDJ48739.1 - 0.029 15.4 8.3 0.029 15.4 8.3 1.9 1 1 1 2 2 2 0 Conotoxin FAM176 PF14851.6 CDJ48739.1 - 0.029 14.0 2.1 0.03 14.0 2.1 1.1 1 0 0 1 1 1 0 FAM176 family SID-1_RNA_chan PF13965.6 CDJ48739.1 - 0.036 12.5 1.1 0.036 12.5 1.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 CDJ48739.1 - 0.038 13.1 4.7 0.04 13.0 4.7 1.0 1 0 0 1 1 1 0 CLN3 protein Peptidase_S49_N PF08496.10 CDJ48739.1 - 0.052 13.6 5.6 0.058 13.4 5.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CD20 PF04103.15 CDJ48739.1 - 0.058 13.5 0.0 0.065 13.3 0.0 1.1 1 0 0 1 1 1 0 CD20-like family OATP PF03137.20 CDJ48739.1 - 0.095 11.0 2.4 0.098 10.9 2.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Frizzled PF01534.17 CDJ48739.1 - 0.1 11.6 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region DUF4446 PF14584.6 CDJ48739.1 - 0.11 12.5 2.5 0.1 12.5 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FHIPEP PF00771.20 CDJ48739.1 - 0.11 11.0 3.9 0.11 10.9 3.9 1.0 1 0 0 1 1 1 0 FHIPEP family Peroxin-13_N PF04088.13 CDJ48739.1 - 0.14 12.5 2.8 0.17 12.2 2.8 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Presenilin PF01080.17 CDJ48739.1 - 0.15 10.8 8.5 0.16 10.7 8.5 1.1 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 CDJ48739.1 - 0.21 10.5 2.2 0.19 10.6 2.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1180 PF06679.12 CDJ48739.1 - 0.29 11.5 6.1 0.35 11.3 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CSG2 PF16965.5 CDJ48739.1 - 0.35 9.8 3.2 0.34 9.8 3.2 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Nucleoside_tran PF01733.18 CDJ48739.1 - 0.46 9.8 1.4 0.48 9.8 1.4 1.0 1 0 0 1 1 1 0 Nucleoside transporter DDHD PF02862.17 CDJ48739.1 - 0.47 10.6 7.1 0.47 10.6 7.1 1.0 1 0 0 1 1 1 0 DDHD domain DcuA_DcuB PF03605.14 CDJ48739.1 - 0.48 9.3 1.2 0.49 9.2 1.2 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Ctr PF04145.15 CDJ48739.1 - 0.5 11.0 3.2 0.49 11.0 3.2 1.1 1 0 0 1 1 1 0 Ctr copper transporter family MCU PF04678.13 CDJ48739.1 - 0.55 10.3 8.4 0.62 10.1 8.4 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter HemY_N PF07219.13 CDJ48739.1 - 0.74 10.0 5.3 1.7 8.9 5.3 1.7 1 1 0 1 1 1 0 HemY protein N-terminus TMEM51 PF15345.6 CDJ48739.1 - 0.77 9.6 12.9 0.91 9.3 12.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 ABC2_membrane_2 PF12679.7 CDJ48739.1 - 1.2 8.3 2.9 1.3 8.2 2.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein 60KD_IMP PF02096.20 CDJ48739.1 - 1.4 8.8 11.4 1.6 8.6 11.4 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein PigN PF04987.14 CDJ48739.1 - 1.5 7.6 4.7 1.6 7.5 4.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) SpoIIP PF07454.11 CDJ48739.1 - 1.6 8.1 10.8 1.7 8.1 10.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2828 PF11443.8 CDJ48739.1 - 1.9 6.5 10.2 2 6.4 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) AIF_C PF14721.6 CDJ48739.1 - 1.9 8.8 6.5 2 8.8 6.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PIP5K PF01504.18 CDJ48739.1 - 2.2 7.4 10.0 2.4 7.3 10.0 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Neur_chan_memb PF02932.16 CDJ48739.1 - 2.5 8.1 7.5 2.6 8.0 7.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Endonuc_Holl PF10107.9 CDJ48739.1 - 3.1 7.6 10.3 3.3 7.5 10.3 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Baculo_PP31 PF05311.11 CDJ48739.1 - 3.2 7.2 10.9 3.3 7.1 10.9 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) EMC3_TMCO1 PF01956.16 CDJ48739.1 - 3.3 7.4 9.1 3.4 7.4 9.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like ALMT PF11744.8 CDJ48739.1 - 8.1 5.2 8.2 8.5 5.1 8.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter WBP-1 PF11669.8 CDJ48739.1 - 9 7.0 9.6 20 5.9 9.6 1.6 1 1 0 1 1 1 0 WW domain-binding protein 1 EIIBC-GUT_N PF03612.14 CDJ48739.1 - 9.9 5.9 9.6 11 5.7 9.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CN_hydrolase PF00795.22 CDJ48740.1 - 8.2e-19 68.0 0.0 8.2e-19 68.0 0.0 2.9 3 1 0 3 3 3 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 CDJ48740.1 - 2e-06 27.1 0.0 0.025 13.7 0.0 2.3 2 0 0 2 2 2 2 NAD synthase SUIM_assoc PF16619.5 CDJ48740.1 - 0.83 9.8 13.1 13 5.9 0.2 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Kelch_6 PF13964.6 CDJ48741.1 - 8.5e-17 60.8 0.0 1.4e-11 44.2 0.0 2.1 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CDJ48741.1 - 3.8e-15 55.2 0.1 1.4e-07 31.0 0.0 2.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CDJ48741.1 - 1.2e-12 47.6 0.0 5.2e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ48741.1 - 2e-07 31.1 0.0 0.0015 18.7 0.0 2.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ48741.1 - 3.3e-05 23.7 0.1 0.024 14.6 0.0 2.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CDJ48741.1 - 7.8e-05 22.6 0.0 0.00084 19.3 0.0 2.4 3 0 0 3 3 3 1 Kelch motif Ubiq_cyt_C_chap PF03981.12 CDJ48742.1 - 1.5e-07 31.6 0.0 1.6e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone SRP9-21 PF05486.12 CDJ48744.1 - 0.0099 16.2 1.3 0.04 14.3 1.3 1.9 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) SR-25 PF10500.9 CDJ48744.1 - 0.17 11.5 16.8 0.2 11.3 16.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 CDJ48744.1 - 0.35 10.7 5.5 0.39 10.5 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Lin-8 PF03353.15 CDJ48744.1 - 0.41 10.2 2.4 0.47 10.0 2.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CCDC106 PF15794.5 CDJ48744.1 - 3.8 7.2 6.7 4.7 6.9 6.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 AF-4 PF05110.13 CDJ48744.1 - 6.1 4.8 18.8 6.4 4.7 18.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Frataxin_Cyay PF01491.16 CDJ48745.1 - 3.1e-20 72.2 0.0 4.3e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain DUF3446 PF11928.8 CDJ48745.1 - 0.026 14.8 7.3 0.026 14.8 7.3 2.6 2 1 0 2 2 2 0 Early growth response N-terminal domain Sugar_tr PF00083.24 CDJ48746.1 - 1.8e-86 290.8 23.8 2.1e-86 290.6 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ48746.1 - 2.5e-36 125.4 56.4 5.7e-26 91.3 33.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDJ48746.1 - 0.0016 16.8 3.8 0.0016 16.8 3.8 1.9 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Holin_SPP1 PF04688.13 CDJ48746.1 - 5.4 7.3 8.5 6.1 7.1 1.8 3.2 2 0 0 2 2 2 0 SPP1 phage holin Clathrin PF00637.20 CDJ48748.1 - 1.6e-172 566.2 20.7 3.2e-29 101.6 0.8 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CDJ48748.1 - 7.6e-27 93.0 0.1 6.5e-26 90.0 0.1 2.7 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 CDJ48748.1 - 1.6e-09 37.6 0.0 1.1e-05 25.5 0.0 4.6 4 0 0 4 4 4 1 Clathrin propeller repeat Coatomer_WDAD PF04053.14 CDJ48748.1 - 1.6e-06 27.5 4.5 0.2 10.6 0.0 3.8 4 0 0 4 4 4 3 Coatomer WD associated region TPR_19 PF14559.6 CDJ48748.1 - 0.21 12.1 10.5 0.97 10.0 0.4 6.2 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ48748.1 - 0.22 11.4 10.2 30 4.6 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ48748.1 - 1.9 8.8 0.0 1.9 8.8 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ48748.1 - 3.6 8.3 14.7 29 5.4 4.0 5.8 4 1 1 5 5 5 0 Tetratricopeptide repeat MMR_HSR1 PF01926.23 CDJ48749.1 - 2.6e-33 114.5 0.1 2.5e-19 69.4 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 CDJ48749.1 - 2.2e-26 92.0 0.1 6.6e-26 90.4 0.1 1.9 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 CDJ48749.1 - 3.4e-14 52.7 0.0 5.1e-10 39.1 0.0 3.1 3 0 0 3 3 3 2 Ferrous iron transport protein B AIG1 PF04548.16 CDJ48749.1 - 1.6e-12 47.2 0.3 1e-05 25.0 0.1 2.4 2 0 0 2 2 2 2 AIG1 family GTP_EFTU PF00009.27 CDJ48749.1 - 4.8e-12 45.8 0.5 4.3e-05 23.2 0.2 4.6 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CDJ48749.1 - 6.4e-12 45.9 0.4 0.0013 18.8 0.1 3.6 2 1 1 3 3 3 2 Dynamin family Gtr1_RagA PF04670.12 CDJ48749.1 - 6e-07 29.1 0.0 0.022 14.1 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ48749.1 - 1.5e-06 28.2 0.1 0.1 12.5 0.0 4.1 4 0 0 4 4 4 2 RsgA GTPase Arf PF00025.21 CDJ48749.1 - 0.00013 21.5 0.4 0.0026 17.2 0.1 2.7 2 1 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 CDJ48749.1 - 0.00043 19.9 0.0 0.0021 17.7 0.0 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CDJ48749.1 - 0.00096 19.4 0.0 0.0042 17.3 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Nuc_deoxyrib_tr PF05014.15 CDJ48749.1 - 0.0017 18.4 0.0 0.92 9.5 0.0 3.6 4 0 0 4 4 4 1 Nucleoside 2-deoxyribosyltransferase Nuc_deoxyri_tr2 PF15891.5 CDJ48749.1 - 0.063 13.6 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like TIR_2 PF13676.6 CDJ48749.1 - 0.095 13.3 0.0 36 5.0 0.0 3.0 2 0 0 2 2 2 0 TIR domain DEAD PF00270.29 CDJ48750.1 - 3.9e-45 153.8 0.1 5.3e-45 153.3 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ48750.1 - 4.8e-29 100.9 0.9 1.7e-28 99.1 0.3 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CDJ48750.1 - 0.0057 17.0 0.1 0.0094 16.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 CDJ48750.1 - 0.041 13.2 0.1 0.085 12.2 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit EphA2_TM PF14575.6 CDJ48754.1 - 0.11 13.3 9.0 1.1 10.2 0.4 3.6 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Abhydrolase_9_N PF15420.6 CDJ48754.1 - 0.13 12.2 26.6 0.12 12.4 22.7 2.3 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Utp14 PF04615.13 CDJ48754.1 - 0.14 10.8 29.3 0.18 10.4 29.3 1.2 1 0 0 1 1 1 0 Utp14 protein KASH PF10541.9 CDJ48754.1 - 1.2 9.5 4.9 2.5 8.5 4.9 1.4 1 0 0 1 1 1 0 Nuclear envelope localisation domain DUF2339 PF10101.9 CDJ48754.1 - 4.4 5.8 35.0 19 3.7 35.7 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) LAP1C PF05609.12 CDJ48754.1 - 10 5.1 33.2 13 4.7 33.2 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TFIIA PF03153.13 CDJ48755.1 - 0.2 11.6 14.4 0.31 11.0 14.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ48756.1 - 0.0033 16.4 13.9 0.0033 16.4 13.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) X PF00739.19 CDJ48756.1 - 0.018 15.2 2.0 0.018 15.2 2.0 1.9 2 0 0 2 2 2 0 Trans-activation protein X PIG-U PF06728.13 CDJ48756.1 - 0.044 12.8 0.1 0.066 12.2 0.1 1.3 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U Rsc14 PF08586.10 CDJ48756.1 - 0.15 12.9 13.6 0.23 12.3 2.6 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit SpoIIP PF07454.11 CDJ48756.1 - 0.51 9.7 17.4 1.7 8.1 4.7 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 CDJ48756.1 - 0.97 9.1 12.1 1.5 8.5 1.5 2.1 2 0 0 2 2 2 0 Connexin PH_4 PF15404.6 CDJ48756.1 - 0.98 9.2 11.6 1.6 8.5 1.7 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4834 PF16118.5 CDJ48756.1 - 1.6 9.8 24.5 2.1 9.3 6.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF966 PF06136.13 CDJ48756.1 - 2.3 7.9 22.2 3.1 7.4 22.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LAP1C PF05609.12 CDJ48756.1 - 2.6 7.0 24.1 3 6.8 24.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hamartin PF04388.12 CDJ48756.1 - 3.4 6.2 19.5 4.7 5.8 19.5 1.2 1 0 0 1 1 1 0 Hamartin protein MPM1 PF17234.2 CDJ48756.1 - 3.5 7.9 23.5 0.66 10.2 5.0 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Maf1 PF09174.10 CDJ48756.1 - 5.7 7.1 15.0 7.8 6.6 4.1 2.1 2 0 0 2 2 2 0 Maf1 regulator DUF4638 PF15472.6 CDJ48756.1 - 7.6 6.2 16.2 5.4 6.7 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) Presenilin PF01080.17 CDJ48757.1 - 0.19 10.5 12.2 0.19 10.5 12.2 1.0 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ48757.1 - 0.2 11.6 35.4 0.21 11.6 35.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EOS1 PF12326.8 CDJ48757.1 - 0.23 11.4 2.1 0.2 11.6 2.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein TMEM51 PF15345.6 CDJ48757.1 - 0.24 11.2 13.2 0.29 10.9 13.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Suf PF05843.14 CDJ48757.1 - 0.26 11.3 13.2 0.29 11.1 13.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ48757.1 - 0.43 10.6 6.6 0.4 10.7 6.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RskA PF10099.9 CDJ48757.1 - 0.47 10.7 22.1 0.86 9.9 22.1 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Glt_symporter PF03616.14 CDJ48757.1 - 0.49 9.0 1.4 0.61 8.7 1.4 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DDHD PF02862.17 CDJ48757.1 - 0.52 10.4 11.0 0.58 10.3 11.0 1.1 1 0 0 1 1 1 0 DDHD domain CobT PF06213.12 CDJ48757.1 - 1.3 8.3 19.5 1.6 8.1 19.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT eIF-3_zeta PF05091.12 CDJ48757.1 - 1.4 7.8 16.4 1.4 7.8 16.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MMR1 PF08505.10 CDJ48757.1 - 1.6 9.0 16.5 1.7 8.9 16.5 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4834 PF16118.5 CDJ48757.1 - 1.8 9.6 15.8 2.7 9.0 15.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ48757.1 - 1.9 8.1 8.2 2.7 7.6 8.2 1.2 1 0 0 1 1 1 0 FAM176 family DUF4175 PF13779.6 CDJ48757.1 - 2 6.2 31.3 2.2 6.1 31.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CbtA PF09490.10 CDJ48757.1 - 2.1 8.1 8.9 2.7 7.7 8.9 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) CPSF100_C PF13299.6 CDJ48757.1 - 2.3 8.4 9.9 3 8.0 9.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Paramyxo_ncap PF00973.19 CDJ48757.1 - 3.1 6.6 12.1 3.4 6.5 12.1 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Connexin PF00029.19 CDJ48757.1 - 3.8 7.2 10.7 4.3 7.0 10.7 1.1 1 0 0 1 1 1 0 Connexin AIF_C PF14721.6 CDJ48757.1 - 5.2 7.4 9.8 6.5 7.1 9.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PIP5K PF01504.18 CDJ48757.1 - 7.1 5.8 14.1 9 5.4 14.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase PAT1 PF09770.9 CDJ48757.1 - 7.3 4.7 25.8 7.6 4.7 25.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.19 CDJ48757.1 - 8.4 4.2 16.6 9.5 4.0 16.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Band_3_cyto PF07565.13 CDJ48757.1 - 9.1 6.0 13.3 11 5.7 13.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Serinc PF03348.15 CDJ48757.1 - 9.8 5.0 7.8 11 4.9 7.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.6 CDJ48758.1 - 0.011 14.2 7.0 0.011 14.2 7.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AAA_11 PF13086.6 CDJ48758.1 - 0.037 13.8 23.2 0.04 13.7 23.2 1.1 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.12 CDJ48758.1 - 0.11 11.1 14.1 0.11 11.0 14.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF2052 PF09747.9 CDJ48758.1 - 0.12 12.5 26.4 0.13 12.4 26.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Exonuc_VII_L PF02601.15 CDJ48758.1 - 0.21 11.1 22.6 0.23 11.0 22.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0564 PF10595.9 CDJ48758.1 - 0.37 9.8 44.0 0.41 9.7 44.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 PPP4R2 PF09184.11 CDJ48758.1 - 0.41 10.2 16.9 0.5 9.9 16.9 1.1 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.12 CDJ48758.1 - 0.45 10.3 33.4 0.5 10.2 33.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 CDJ48758.1 - 0.51 8.6 44.2 0.52 8.5 44.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.16 CDJ48758.1 - 0.84 9.4 17.5 0.93 9.3 17.5 1.2 1 0 0 1 1 1 0 AUX/IAA family Velvet PF11754.8 CDJ48758.1 - 0.85 9.5 23.8 1.1 9.2 23.8 1.3 1 0 0 1 1 1 0 Velvet factor DUF913 PF06025.12 CDJ48758.1 - 1.4 7.8 15.6 2.1 7.3 15.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CCSAP PF15748.5 CDJ48758.1 - 3.4 7.8 35.8 4 7.5 35.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FAM60A PF15396.6 CDJ48758.1 - 3.8 7.5 26.8 4.5 7.2 26.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TCP PF03634.13 CDJ48758.1 - 4.1 7.9 31.9 5.2 7.6 31.9 1.1 1 0 0 1 1 1 0 TCP family transcription factor Silic_transp PF03842.13 CDJ48758.1 - 5.6 5.2 6.9 8.3 4.6 6.9 1.4 1 1 0 1 1 1 0 Silicon transporter Nop53 PF07767.11 CDJ48758.1 - 6.9 5.9 38.8 8 5.7 38.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Endostatin PF06482.11 CDJ48758.1 - 7.8 5.9 28.2 9 5.7 28.2 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Serinc PF03348.15 CDJ48758.1 - 8.2 5.2 19.9 13 4.6 19.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) eIF-3_zeta PF05091.12 CDJ48758.1 - 9 5.1 37.1 13 4.6 37.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AMP-binding PF00501.28 CDJ48759.1 - 2.1e-06 26.6 3.2 2.1e-06 26.6 3.2 2.9 1 1 2 3 3 3 1 AMP-binding enzyme CCDC106 PF15794.5 CDJ48759.1 - 4.9e-06 26.4 6.6 4.9e-06 26.4 6.6 3.2 2 1 1 3 3 2 1 Coiled-coil domain-containing protein 106 SR-25 PF10500.9 CDJ48759.1 - 0.0012 18.5 21.1 0.0012 18.5 21.1 2.9 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein MID_MedPIWI PF18296.1 CDJ48759.1 - 0.067 13.0 31.6 0.83 9.4 20.2 2.5 2 0 0 2 2 2 0 MID domain of medPIWI Peptidase_S64 PF08192.11 CDJ48759.1 - 0.076 11.5 22.3 0.12 10.9 22.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Suf PF05843.14 CDJ48759.1 - 0.1 12.5 31.5 1.3 8.9 19.9 2.9 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) PIP5K PF01504.18 CDJ48759.1 - 0.14 11.4 10.6 0.17 11.0 2.7 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase ASD2 PF08687.11 CDJ48759.1 - 1.2 8.7 24.6 0.29 10.7 13.2 2.4 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 MMR1 PF08505.10 CDJ48759.1 - 1.4 9.2 30.9 1.8 8.8 15.7 2.6 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein TCP PF03634.13 CDJ48759.1 - 1.7 9.2 33.5 0.55 10.8 13.9 2.8 3 0 0 3 3 3 0 TCP family transcription factor rRNA_processing PF08524.11 CDJ48759.1 - 2.7 8.0 25.8 3.1 7.8 2.5 2.4 2 0 0 2 2 2 0 rRNA processing CCSAP PF15748.5 CDJ48759.1 - 2.8 8.1 35.3 1.6 8.9 16.3 2.8 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Prp31_C PF09785.9 CDJ48759.1 - 4 8.4 13.5 3.9 8.4 4.4 2.8 2 0 0 2 2 2 0 Prp31 C terminal domain eIF3g PF12353.8 CDJ48759.1 - 4.8 7.6 11.9 0.67 10.3 4.9 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Gti1_Pac2 PF09729.9 CDJ48759.1 - 9.3 6.3 20.3 3.9 7.5 0.8 2.5 2 0 0 2 2 2 0 Gti1/Pac2 family HC2 PF07382.11 CDJ48760.1 - 1.9e-11 44.5 34.3 7.8e-10 39.2 12.7 2.5 1 1 2 3 3 3 3 Histone H1-like nucleoprotein HC2 SICA_C PF12879.7 CDJ48760.1 - 0.00015 21.8 6.9 0.066 13.2 0.4 3.7 1 1 2 3 3 3 3 SICA C-terminal inner membrane domain Sporozoite_P67 PF05642.11 CDJ48761.1 - 0.00092 17.4 1.3 0.00092 17.4 1.3 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Presenilin PF01080.17 CDJ48761.1 - 0.014 14.2 2.0 0.015 14.1 2.0 1.1 1 0 0 1 1 1 0 Presenilin Bac_GDH PF05088.12 CDJ48761.1 - 0.023 12.2 0.0 0.023 12.2 0.0 1.4 2 0 0 2 2 1 0 Bacterial NAD-glutamate dehydrogenase Ndc1_Nup PF09531.10 CDJ48761.1 - 0.22 10.2 2.9 0.22 10.2 2.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SpoIIP PF07454.11 CDJ48761.1 - 0.28 10.6 4.4 0.35 10.3 4.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4770 PF15994.5 CDJ48761.1 - 0.5 10.6 7.0 0.76 10.0 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4820 PF16091.5 CDJ48761.1 - 1.3 8.3 10.9 2 7.7 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NPR3 PF03666.13 CDJ48761.1 - 2.4 6.8 5.6 2.7 6.7 5.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIA PF03153.13 CDJ48761.1 - 2.8 7.8 21.7 4.3 7.2 21.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 CDJ48761.1 - 3 6.0 5.6 3.5 5.8 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 CDJ48761.1 - 3.2 6.5 9.1 4.2 6.1 9.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.6 CDJ48761.1 - 3.2 7.4 7.7 5.6 6.6 7.7 1.4 1 0 0 1 1 1 0 FAM176 family DUF4834 PF16118.5 CDJ48761.1 - 4 8.5 14.0 8.1 7.5 14.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ48761.1 - 6.4 6.3 30.0 0.19 11.3 24.1 1.4 2 0 0 2 2 2 0 Spt20 family BRF1 PF07741.13 CDJ48761.1 - 8.5 6.8 11.1 15 6.0 11.1 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain ELFV_dehydrog PF00208.21 CDJ48762.1 - 3.5e-14 53.1 0.1 4.5e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TFIIA PF03153.13 CDJ48763.1 - 1.1e-06 29.0 17.0 1.4e-06 28.6 17.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 CDJ48763.1 - 0.0015 18.3 7.0 0.0043 16.8 1.3 2.2 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein SARAF PF06682.12 CDJ48763.1 - 0.0032 17.2 4.8 0.0032 17.2 4.8 2.1 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis DUF3371 PF11851.8 CDJ48763.1 - 0.0044 18.1 14.1 0.0044 18.1 14.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3371) TcdA_TcdB_pore PF12920.7 CDJ48763.1 - 3.7 5.7 11.8 5.4 5.1 11.8 1.3 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain SRP9-21 PF05486.12 CDJ48763.1 - 3.8 8.0 8.8 0.36 11.2 0.4 2.8 3 0 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) SPX PF03105.19 CDJ48763.1 - 6.5 6.6 30.3 58 3.4 30.3 1.9 1 1 0 1 1 1 0 SPX domain DUF1501 PF07394.12 CDJ48763.1 - 9.4 5.2 15.2 13 4.7 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Presenilin PF01080.17 CDJ48764.1 - 0.41 9.4 4.0 0.38 9.5 4.0 1.0 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 CDJ48764.1 - 0.63 9.4 16.6 0.6 9.5 16.6 1.0 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CDJ48764.1 - 1.2 8.4 14.9 1.3 8.3 14.9 1.0 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 CDJ48764.1 - 3.2 7.5 11.1 4.4 7.1 11.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPR3 PF03666.13 CDJ48764.1 - 4.7 5.9 5.4 5.1 5.8 5.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Raftlin PF15250.6 CDJ48764.1 - 5.4 5.6 7.4 6.3 5.4 7.4 1.1 1 0 0 1 1 1 0 Raftlin eIF-3c_N PF05470.12 CDJ48764.1 - 7.6 4.7 8.4 8.8 4.5 8.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus IFT57 PF10498.9 CDJ48764.1 - 7.7 5.4 13.1 9.6 5.1 13.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 V_ATPase_I PF01496.19 CDJ48764.1 - 9.3 4.0 8.4 11 3.7 8.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ABC_tran PF00005.27 CDJ48765.1 - 7.7e-16 58.8 0.0 3e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ48765.1 - 1.3e-07 31.3 2.7 0.001 18.5 0.0 3.1 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ48765.1 - 8.3e-07 29.1 0.5 0.011 15.5 0.1 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ48765.1 - 0.00085 19.0 0.1 0.0017 18.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CDJ48765.1 - 0.0021 18.3 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CDJ48765.1 - 0.0049 17.4 0.0 0.0073 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CDJ48765.1 - 0.008 15.9 0.0 0.054 13.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ48765.1 - 0.0099 15.8 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CDJ48765.1 - 0.023 15.1 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 CDJ48765.1 - 0.032 14.2 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CDJ48765.1 - 0.048 13.2 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 CDJ48765.1 - 0.053 12.7 0.1 0.24 10.5 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 CDJ48765.1 - 0.079 13.0 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CDJ48765.1 - 0.09 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CDJ48765.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 CDJ48765.1 - 0.16 12.1 0.0 0.36 10.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_13 PF13166.6 CDJ48765.1 - 0.24 10.0 0.0 0.61 8.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.7 CDJ48766.1 - 0.00069 19.5 0.7 0.00069 19.5 0.7 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDJ48766.1 - 0.0084 16.0 0.1 0.0084 16.0 0.1 3.0 3 0 0 3 3 3 1 F-box domain DUF572 PF04502.13 CDJ48767.1 - 0.37 10.4 28.6 0.57 9.7 28.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Exonuc_VII_L PF02601.15 CDJ48768.1 - 0.49 9.9 33.7 0.59 9.7 33.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit RR_TM4-6 PF06459.12 CDJ48768.1 - 0.82 9.5 39.0 1 9.1 39.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ48768.1 - 2.5 8.0 29.5 3 7.8 29.5 1.0 1 0 0 1 1 1 0 Protein Family FAM60A CCSAP PF15748.5 CDJ48768.1 - 4 7.5 40.9 5 7.2 40.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4045 PF13254.6 CDJ48768.1 - 8.1 6.0 34.7 8.5 5.9 34.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Endostatin PF06482.11 CDJ48768.1 - 8.6 5.7 30.4 12 5.2 30.4 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin AAA_11 PF13086.6 CDJ48768.1 - 9.3 5.9 31.0 11 5.7 31.0 1.1 1 0 0 1 1 1 0 AAA domain SID-1_RNA_chan PF13965.6 CDJ48769.1 - 0.062 11.7 14.1 0.087 11.2 14.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LSM PF01423.22 CDJ48770.1 - 0.002 17.8 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 LSM domain RskA PF10099.9 CDJ48770.1 - 0.0033 17.7 7.0 0.0033 17.7 7.0 2.1 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Trp_halogenase PF04820.14 CDJ48770.1 - 0.021 13.7 1.1 0.033 13.0 1.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase PH_10 PF15411.6 CDJ48770.1 - 0.031 14.5 0.4 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Corona_nucleoca PF00937.18 CDJ48770.1 - 0.89 8.5 10.3 1.3 8.0 10.3 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PepSY_TM PF03929.16 CDJ48770.1 - 0.95 9.1 6.5 4.1 7.0 1.0 2.0 2 0 0 2 2 2 0 PepSY-associated TM region Presenilin PF01080.17 CDJ48770.1 - 1.8 7.2 5.8 2.4 6.8 5.8 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_60s PF00428.19 CDJ48770.1 - 3.7 8.2 13.0 6.7 7.4 13.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ48771.1 - 5.9e-05 22.8 6.1 5.9e-05 22.8 6.1 5.9 4 2 1 5 5 5 2 Spt20 family DUF2722 PF10846.8 CDJ48771.1 - 0.00057 19.0 5.5 0.00057 19.0 5.5 6.1 3 1 2 6 6 6 2 Protein of unknown function (DUF2722) DUF4441 PF14536.6 CDJ48771.1 - 0.013 15.6 1.1 0.013 15.6 1.1 4.5 4 1 0 4 4 4 0 Domain of unknown function (DUF4441) MAM33 PF02330.16 CDJ48771.1 - 0.48 10.3 0.0 0.48 10.3 0.0 4.7 4 1 0 4 4 4 0 Mitochondrial glycoprotein eIF-3_zeta PF05091.12 CDJ48771.1 - 0.91 8.4 61.8 0.013 14.5 24.0 4.0 4 0 0 4 4 4 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Adaptin_binding PF10199.9 CDJ48772.1 - 1.3 9.6 6.7 6.7 7.4 6.6 2.2 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Dzip-like_N PF13815.6 CDJ48772.1 - 2.7 8.0 8.9 0.6 10.1 4.6 2.0 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal RskA PF10099.9 CDJ48773.1 - 0.00061 20.1 4.5 0.00068 20.0 4.5 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF1645 PF07816.11 CDJ48773.1 - 0.02 15.5 17.9 0.024 15.2 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) SprA-related PF12118.8 CDJ48773.1 - 0.025 13.8 21.1 0.034 13.3 21.1 1.2 1 0 0 1 1 1 0 SprA-related family MID_MedPIWI PF18296.1 CDJ48773.1 - 0.042 13.6 11.6 0.057 13.2 11.6 1.1 1 0 0 1 1 1 0 MID domain of medPIWI FAM199X PF15814.5 CDJ48773.1 - 0.072 12.1 21.1 0.087 11.9 21.1 1.0 1 0 0 1 1 1 0 Protein family FAM199X TCP PF03634.13 CDJ48773.1 - 0.11 13.0 12.7 0.15 12.6 12.7 1.2 1 0 0 1 1 1 0 TCP family transcription factor SpecificRecomb PF10136.9 CDJ48773.1 - 0.2 10.0 7.4 0.2 9.9 7.4 1.0 1 0 0 1 1 1 0 Site-specific recombinase Ashwin PF15323.6 CDJ48773.1 - 0.22 11.5 14.2 0.24 11.4 14.2 1.1 1 0 0 1 1 1 0 Developmental protein PA26 PF04636.13 CDJ48773.1 - 0.34 9.8 8.0 0.36 9.7 8.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HA2 PF04408.23 CDJ48773.1 - 0.36 11.1 4.9 0.42 10.9 4.9 1.3 1 1 0 1 1 1 0 Helicase associated domain (HA2) SSP160 PF06933.11 CDJ48773.1 - 0.39 8.8 18.8 0.45 8.7 18.8 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Synuclein PF01387.17 CDJ48773.1 - 0.54 10.5 4.8 0.64 10.2 4.8 1.1 1 0 0 1 1 1 0 Synuclein Velvet PF11754.8 CDJ48773.1 - 0.64 9.9 14.4 0.82 9.6 14.4 1.2 1 0 0 1 1 1 0 Velvet factor FliX PF10768.9 CDJ48773.1 - 1.2 9.7 14.1 1.5 9.4 14.1 1.1 1 0 0 1 1 1 0 Class II flagellar assembly regulator Suf PF05843.14 CDJ48773.1 - 1.8 8.5 15.3 2 8.3 15.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Senescence_reg PF04520.13 CDJ48773.1 - 2.5 8.9 13.5 2.9 8.7 13.5 1.1 1 0 0 1 1 1 0 Senescence regulator Corona_nucleoca PF00937.18 CDJ48773.1 - 2.5 7.0 20.0 3.2 6.7 20.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SOBP PF15279.6 CDJ48773.1 - 3.2 8.3 17.9 3.5 8.1 17.9 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein UPF0239 PF06783.11 CDJ48773.1 - 3.5 7.9 9.2 1 9.6 3.6 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) EphA2_TM PF14575.6 CDJ48773.1 - 4.1 8.4 8.8 0.97 10.4 4.5 2.0 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SMYLE_N PF18615.1 CDJ48773.1 - 4.6 6.7 15.9 4.9 6.6 15.9 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Presenilin PF01080.17 CDJ48773.1 - 8.8 5.0 16.3 11 4.7 16.3 1.1 1 0 0 1 1 1 0 Presenilin MitMem_reg PF13012.6 CDJ48774.1 - 1.2e-20 74.0 0.1 2.3e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Amino_oxidase PF01593.24 CDJ48775.1 - 1.7e-06 27.6 0.1 1.7e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Utp14 PF04615.13 CDJ48775.1 - 6.3 5.2 62.0 1.6 7.2 32.9 2.1 2 0 0 2 2 2 0 Utp14 protein Sporozoite_P67 PF05642.11 CDJ48776.1 - 9.2e-06 24.0 2.8 0.00083 17.6 0.0 2.2 1 1 1 2 2 2 1 Sporozoite P67 surface antigen RskA PF10099.9 CDJ48776.1 - 0.00031 21.1 46.3 0.00065 20.0 14.7 7.1 2 2 3 6 6 6 2 Anti-sigma-K factor rskA NPR3 PF03666.13 CDJ48776.1 - 0.0023 16.8 10.0 0.0023 16.8 10.0 3.0 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 RLL PF10036.9 CDJ48776.1 - 0.0035 17.2 10.3 0.0035 17.2 10.3 3.6 3 0 0 3 3 3 1 RNA transcription, translation and transport factor protein PPL5 PF18168.1 CDJ48776.1 - 0.022 14.1 0.5 0.022 14.1 0.5 3.1 3 0 0 3 3 3 0 Prim-pol family 5 DUF3381 PF11861.8 CDJ48776.1 - 0.59 9.9 39.7 0.043 13.6 11.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) SKA1 PF07160.12 CDJ48776.1 - 8.3 6.2 30.1 0.25 11.2 4.4 3.5 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 RskA PF10099.9 CDJ48777.1 - 0.00021 21.6 22.9 0.00021 21.6 22.9 6.8 3 2 2 5 5 5 3 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ48777.1 - 0.00036 20.2 60.4 0.0025 17.5 19.9 4.3 4 0 0 4 4 4 4 Spt20 family DUF2722 PF10846.8 CDJ48777.1 - 0.0041 16.1 42.8 0.029 13.3 2.5 4.2 4 0 0 4 4 4 3 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ48777.1 - 0.0043 16.7 3.5 0.0043 16.7 3.5 4.7 4 1 1 5 5 5 3 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ48777.1 - 0.01 16.5 3.7 0.01 16.5 3.7 5.3 6 0 0 6 6 6 0 Immortalisation up-regulated protein Otopetrin PF03189.13 CDJ48777.1 - 0.081 11.7 0.0 0.17 10.7 0.0 1.8 1 1 0 1 1 1 0 Otopetrin Activator_LAG-3 PF11498.8 CDJ48777.1 - 0.49 9.3 71.3 0.13 11.2 5.3 4.3 4 0 0 4 4 4 0 Transcriptional activator LAG-3 TPR_2 PF07719.17 CDJ48777.1 - 4.4 7.7 34.4 0.16 12.2 4.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Sporozoite_P67 PF05642.11 CDJ48777.1 - 7.6 4.5 11.4 0.27 9.3 0.2 2.8 3 0 0 3 3 3 0 Sporozoite P67 surface antigen Cpn60_TCP1 PF00118.24 CDJ48778.1 - 3.1e-145 484.6 4.7 3.8e-145 484.3 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2722 PF10846.8 CDJ48779.1 - 0.00032 19.8 4.1 0.00033 19.7 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4207 PF13904.6 CDJ48779.1 - 0.0011 18.7 8.9 0.0013 18.5 8.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) Spt20 PF12090.8 CDJ48779.1 - 0.0021 17.7 12.2 0.0021 17.7 12.2 1.2 1 0 0 1 1 1 1 Spt20 family SseC PF04888.12 CDJ48779.1 - 0.052 13.1 32.9 0.062 12.9 32.9 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF4834 PF16118.5 CDJ48779.1 - 0.43 11.6 3.3 0.6 11.1 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM108 PF15759.5 CDJ48779.1 - 0.48 9.4 16.2 0.61 9.0 16.2 1.2 1 0 0 1 1 1 0 TMEM108 family Hamartin PF04388.12 CDJ48779.1 - 1.8 7.1 4.7 2.3 6.8 4.7 1.1 1 0 0 1 1 1 0 Hamartin protein GREB1 PF15782.5 CDJ48779.1 - 2.4 5.2 5.5 2.6 5.1 5.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RLL PF10036.9 CDJ48779.1 - 6.1 6.6 13.6 8.8 6.1 13.6 1.2 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein DUF5585 PF17823.1 CDJ48779.1 - 7.2 5.4 29.2 8.4 5.2 29.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) DAGAT PF03982.13 CDJ48780.1 - 9.1e-10 37.9 0.0 9.2e-10 37.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Hormone_recep PF00104.30 CDJ48780.1 - 0.019 14.5 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor SR-25 PF10500.9 CDJ48781.1 - 6.8e-06 25.9 104.3 0.00021 21.0 25.6 5.6 4 2 1 5 5 5 4 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ48781.1 - 0.0084 15.8 4.9 0.0084 15.8 4.9 7.1 4 2 1 5 5 5 2 Spt20 family RT_RNaseH PF17917.1 CDJ48782.1 - 9.7e-22 77.2 0.2 2e-21 76.2 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ48782.1 - 4.2e-11 42.8 0.0 8.8e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Treslin_N PF15292.6 CDJ48782.1 - 0.22 9.8 0.1 0.33 9.2 0.1 1.1 1 0 0 1 1 1 0 Treslin N-terminus rve PF00665.26 CDJ48783.1 - 2.9e-12 46.8 0.0 5.6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ48783.1 - 0.0076 16.1 0.2 0.019 14.9 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 CDJ48783.1 - 0.046 13.5 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain Hormone_recep PF00104.30 CDJ48783.1 - 0.2 11.2 0.6 1 8.9 0.1 1.9 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor RAP1 PF07218.11 CDJ48784.1 - 0.053 11.8 4.8 0.063 11.6 4.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Hamartin PF04388.12 CDJ48784.1 - 4.8 5.7 34.1 5.8 5.5 34.1 1.1 1 0 0 1 1 1 0 Hamartin protein Hid1 PF12722.7 CDJ48784.1 - 9 4.3 38.4 9.2 4.2 38.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SR-25 PF10500.9 CDJ48785.1 - 2.5e-05 24.0 22.5 2.8e-05 23.8 22.5 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ48785.1 - 3.3 6.4 12.4 3.6 6.3 12.4 1.0 1 0 0 1 1 1 0 Presenilin YbgS PF13985.6 CDJ48785.1 - 3.5 7.9 17.7 4.7 7.5 17.7 1.3 1 1 0 1 1 1 0 YbgS-like protein CCDC106 PF15794.5 CDJ48785.1 - 4.2 7.0 15.5 4.6 6.9 15.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4228 PF14009.6 CDJ48785.1 - 6.8 7.0 12.2 10 6.5 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF5521 PF17659.1 CDJ48785.1 - 8 4.2 9.6 10 3.8 9.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Macoilin PF09726.9 CDJ48785.1 - 8.5 4.8 12.9 11 4.5 12.9 1.2 1 0 0 1 1 1 0 Macoilin family SOBP PF15279.6 CDJ48786.1 - 5 7.7 26.4 6.5 7.3 26.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SLC12 PF03522.15 CDJ48786.1 - 7.4 5.5 32.1 9.8 5.1 32.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 FAM76 PF16046.5 CDJ48787.1 - 0.00054 19.4 2.0 0.00054 19.4 2.0 3.1 3 0 0 3 3 3 2 FAM76 protein AAA_23 PF13476.6 CDJ48787.1 - 0.0026 18.3 8.5 0.0026 18.3 8.5 2.2 2 0 0 2 2 2 1 AAA domain TMEM51 PF15345.6 CDJ48787.1 - 0.0076 16.1 1.5 0.0076 16.1 1.5 3.6 3 1 0 3 3 3 1 Transmembrane protein 51 DUF4692 PF15763.5 CDJ48787.1 - 0.011 16.2 5.5 0.011 16.2 5.5 4.2 3 1 1 4 4 4 0 Regulator of human erythroid cell expansion (RHEX) EPL1 PF10513.9 CDJ48787.1 - 2.4 8.5 48.9 0.14 12.5 8.2 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like SART-1 PF03343.13 CDJ48787.1 - 6.8 5.1 37.0 0.079 11.5 20.9 2.0 2 0 0 2 2 2 0 SART-1 family BAF1_ABF1 PF04684.13 CDJ48787.1 - 8.1 5.4 49.6 4.3 6.3 10.6 2.2 1 1 1 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF2722 PF10846.8 CDJ48789.1 - 0.0036 16.3 13.6 0.0036 16.3 13.6 3.2 3 1 0 3 3 3 2 Protein of unknown function (DUF2722) Hira PF07569.11 CDJ48789.1 - 0.053 13.2 0.1 0.053 13.2 0.1 3.6 3 2 1 4 4 4 0 TUP1-like enhancer of split Spt20 PF12090.8 CDJ48789.1 - 1.2 8.7 35.9 0.2 11.3 19.4 2.8 3 0 0 3 3 3 0 Spt20 family RskA PF10099.9 CDJ48791.1 - 0.00034 21.0 6.1 0.00034 21.0 6.1 4.1 2 1 2 4 4 3 2 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ48791.1 - 0.00045 20.3 27.1 0.00058 20.0 27.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ48791.1 - 0.0021 17.1 6.6 0.0021 17.1 6.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ48791.1 - 0.0028 16.4 15.5 0.0028 16.4 15.5 1.8 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ48791.1 - 0.0064 16.1 15.1 0.0064 16.1 15.1 2.0 2 0 0 2 2 2 1 Spt20 family Secretin PF00263.21 CDJ48791.1 - 0.011 15.3 4.0 0.024 14.3 4.0 1.4 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein SUZ PF12752.7 CDJ48791.1 - 0.19 12.5 0.2 0.19 12.5 0.2 2.9 3 0 0 3 3 3 0 SUZ domain DUF2232 PF09991.9 CDJ48791.1 - 0.29 10.3 2.1 0.6 9.2 2.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Stig1 PF04885.13 CDJ48791.1 - 0.64 10.5 11.3 0.47 10.9 1.4 2.4 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 DUF4079 PF13301.6 CDJ48791.1 - 4.6 7.4 9.1 0.13 12.5 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) BST2 PF16716.5 CDJ48791.1 - 4.7 7.9 23.9 13 6.5 0.3 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 SR-25 PF10500.9 CDJ48791.1 - 6.5 6.3 26.2 0.15 11.6 11.5 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CDJ48791.1 - 6.6 4.9 4.9 9.9 4.3 4.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Trp_oprn_chp PF09534.10 CDJ48791.1 - 6.7 6.5 48.2 0.57 10.0 20.3 3.3 2 1 1 3 3 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sad1_UNC PF07738.13 CDJ48793.1 - 4.1e-21 75.4 0.0 3.1e-10 40.2 0.0 2.8 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF2408 PF10303.9 CDJ48793.1 - 0.016 15.8 8.1 0.016 15.8 8.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) RskA PF10099.9 CDJ48793.1 - 0.14 12.5 0.0 0.14 12.5 0.0 6.1 2 1 3 5 5 5 0 Anti-sigma-K factor rskA DUF1091 PF06477.13 CDJ48793.1 - 0.14 12.6 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) FapA PF03961.13 CDJ48793.1 - 4 5.9 8.4 7.9 5.0 8.4 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 CDJ48793.1 - 7.7 5.3 28.2 1.2e+02 1.4 28.2 2.5 1 1 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 CDJ48797.1 - 1.2 7.6 6.7 1.6 7.2 6.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2813 PF11398.8 CDJ48797.1 - 6.4 5.9 19.7 10 5.3 19.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2813) DUF1645 PF07816.11 CDJ48798.1 - 0.43 11.1 37.5 0.02 15.5 4.2 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1645) Cwf_Cwc_15 PF04889.12 CDJ48798.1 - 2.4 7.8 22.3 0.26 11.0 7.4 3.3 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein HD-ZIP_N PF04618.12 CDJ48799.1 - 1.8 9.1 11.3 4.3 7.9 11.3 1.7 1 0 0 1 1 1 0 HD-ZIP protein N terminus Rcd1 PF04078.13 CDJ48800.1 - 2.4e-14 53.3 0.1 2.9e-14 53.0 0.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TetR_C_31 PF17940.1 CDJ48800.1 - 0.032 14.4 0.1 0.37 11.0 0.1 1.9 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_6 PF13174.6 CDJ48800.1 - 0.038 14.6 0.6 0.078 13.7 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TetR_C_11 PF16859.5 CDJ48800.1 - 0.11 12.8 0.1 0.2 12.0 0.1 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TFIIA PF03153.13 CDJ48802.1 - 0.98 9.3 19.1 1.1 9.2 19.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ48803.1 - 0.00039 19.6 9.1 0.00046 19.4 9.1 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Myc_N PF01056.18 CDJ48803.1 - 0.0031 17.5 15.6 0.005 16.8 15.6 1.2 1 0 0 1 1 1 1 Myc amino-terminal region DUF4179 PF13786.6 CDJ48803.1 - 0.0052 17.2 2.8 0.027 14.9 1.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4179) VIR_N PF15912.5 CDJ48803.1 - 0.008 15.8 3.0 0.014 15.0 3.0 1.3 1 0 0 1 1 1 1 Virilizer, N-terminal SID-1_RNA_chan PF13965.6 CDJ48803.1 - 0.26 9.7 1.0 0.33 9.3 1.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Menin PF05053.13 CDJ48803.1 - 0.44 8.9 13.3 0.58 8.5 13.3 1.1 1 0 0 1 1 1 0 Menin PPP4R2 PF09184.11 CDJ48803.1 - 0.61 9.6 16.6 0.92 9.0 16.6 1.2 1 0 0 1 1 1 0 PPP4R2 UPF0565 PF10561.9 CDJ48803.1 - 0.67 9.1 6.8 1.1 8.4 6.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Sporozoite_P67 PF05642.11 CDJ48803.1 - 1.4 6.9 8.5 1.8 6.5 8.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RR_TM4-6 PF06459.12 CDJ48803.1 - 2.4 7.9 26.9 0.73 9.6 24.0 1.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EXS PF03124.14 CDJ48804.1 - 3.7e-08 33.1 0.2 6e-08 32.4 0.2 1.3 1 0 0 1 1 1 1 EXS family Mitofilin PF09731.9 CDJ48804.1 - 0.0011 17.9 5.2 0.0011 17.9 5.2 2.0 2 0 0 2 2 2 1 Mitochondrial inner membrane protein DUF2722 PF10846.8 CDJ48804.1 - 0.0055 15.7 3.7 0.0055 15.7 3.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ48804.1 - 0.022 14.4 25.7 0.022 14.4 12.7 2.2 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 CDJ48804.1 - 0.059 14.3 3.8 0.47 11.4 0.3 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) ANAPC_CDC26 PF10471.9 CDJ48804.1 - 6.8 7.6 26.6 0.75 10.7 8.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 JUPITER PF17054.5 CDJ48807.1 - 0.016 14.7 9.9 0.02 14.4 9.9 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter CCSAP PF15748.5 CDJ48807.1 - 0.065 13.4 33.9 0.089 13.0 33.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated BAF1_ABF1 PF04684.13 CDJ48807.1 - 0.2 10.7 29.6 0.26 10.3 29.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RAP1 PF07218.11 CDJ48807.1 - 0.69 8.1 9.6 0.85 7.8 9.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TFIIA PF03153.13 CDJ48807.1 - 0.82 9.6 60.1 1.5 8.8 60.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S15 PF02129.18 CDJ48807.1 - 0.85 9.2 17.8 1.3 8.5 17.8 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) TAF1D PF15333.6 CDJ48807.1 - 1.4 8.7 19.4 0.44 10.3 2.3 2.2 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D O-antigen_lig PF13425.6 CDJ48807.1 - 2.2 6.9 8.3 2.9 6.6 8.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PAT1 PF09770.9 CDJ48807.1 - 2.4 6.3 41.2 3 6.0 41.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SpoIIP PF07454.11 CDJ48807.1 - 3.9 6.8 24.9 0.37 10.2 19.0 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CDK5_activator PF03261.15 CDJ48807.1 - 5.4 6.4 22.6 7 6.1 22.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Lin-8 PF03353.15 CDJ48808.1 - 0.0015 18.2 12.2 0.0018 17.9 12.2 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.13 CDJ48808.1 - 0.002 18.0 10.4 0.003 17.4 10.4 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain PRP1_N PF06424.12 CDJ48808.1 - 0.007 16.8 13.2 0.011 16.1 13.2 1.3 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal Slu7 PF11708.8 CDJ48808.1 - 0.0087 15.8 3.5 0.0087 15.8 3.5 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor PA26 PF04636.13 CDJ48808.1 - 0.059 12.3 12.0 0.079 11.9 12.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Endostatin PF06482.11 CDJ48808.1 - 0.063 12.7 12.3 0.091 12.2 12.3 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Suf PF05843.14 CDJ48808.1 - 0.075 13.0 25.3 0.15 12.0 25.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ALMT PF11744.8 CDJ48808.1 - 0.094 11.5 9.1 0.12 11.2 9.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Fumble PF03630.14 CDJ48808.1 - 0.097 11.8 6.0 0.14 11.3 6.0 1.2 1 0 0 1 1 1 0 Fumble PAT1 PF09770.9 CDJ48808.1 - 0.12 10.6 26.5 0.15 10.3 26.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CCSAP PF15748.5 CDJ48808.1 - 0.13 12.4 16.7 0.19 11.9 16.7 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated V_ATPase_I PF01496.19 CDJ48808.1 - 0.16 9.9 13.7 0.21 9.5 13.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dpy19 PF10034.9 CDJ48808.1 - 0.24 9.5 7.3 0.96 7.6 7.3 1.8 1 1 0 1 1 1 0 Q-cell neuroblast polarisation RR_TM4-6 PF06459.12 CDJ48808.1 - 0.5 10.2 15.6 0.82 9.4 15.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CDJ48808.1 - 0.55 7.3 16.0 0.6 7.2 16.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_22 PF13401.6 CDJ48808.1 - 0.62 10.3 8.6 1.3 9.3 8.6 1.5 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.7 CDJ48808.1 - 0.72 7.9 14.8 0.95 7.5 14.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spore_YhcN_YlaJ PF09580.10 CDJ48808.1 - 0.72 9.9 14.7 1.3 9.1 14.7 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) MAT1 PF06391.13 CDJ48808.1 - 0.83 9.4 25.4 1.5 8.6 25.4 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 PIP5K PF01504.18 CDJ48808.1 - 0.92 8.7 11.3 1.4 8.1 11.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SLC12 PF03522.15 CDJ48808.1 - 1 8.3 18.4 1.3 7.9 18.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4050 PF13259.6 CDJ48808.1 - 1.2 9.5 13.9 2.3 8.5 13.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Tim54 PF11711.8 CDJ48808.1 - 1.3 7.7 14.4 2.2 6.9 14.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 IML1 PF12257.8 CDJ48808.1 - 1.9 7.6 8.4 2.7 7.0 8.4 1.2 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 DUF4820 PF16091.5 CDJ48808.1 - 2.2 7.6 16.0 4 6.7 16.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Draxin PF15550.6 CDJ48808.1 - 3.6 7.4 14.6 5.4 6.8 14.6 1.2 1 0 0 1 1 1 0 Draxin DUF2126 PF09899.9 CDJ48808.1 - 4.5 5.2 11.7 7.2 4.5 11.7 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) FAM60A PF15396.6 CDJ48808.1 - 4.5 7.2 14.5 9.7 6.1 14.5 1.5 1 0 0 1 1 1 0 Protein Family FAM60A ORC_WH_C PF18137.1 CDJ48808.1 - 5.5 7.1 18.3 23 5.1 0.3 2.4 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Thg1C PF14413.6 CDJ48808.1 - 7.8 6.7 16.7 13 6.0 0.5 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain MDM10 PF12519.8 CDJ48808.1 - 9.4 5.0 16.2 13 4.5 16.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CNDH2_M PF16869.5 CDJ48808.1 - 9.4 6.9 13.5 2.3 8.9 3.2 2.4 2 0 0 2 2 2 0 PF16858 Presenilin PF01080.17 CDJ48808.1 - 9.5 4.9 26.2 0.26 10.0 18.3 1.9 2 0 0 2 2 2 0 Presenilin Mito_carr PF00153.27 CDJ48810.1 - 3.8e-23 81.2 0.1 5.7e-13 48.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein SUIM_assoc PF16619.5 CDJ48811.1 - 0.046 13.8 6.5 0.022 14.8 3.5 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4611 PF15387.6 CDJ48811.1 - 0.32 11.2 6.7 0.15 12.3 1.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MFS_1 PF07690.16 CDJ48812.1 - 7.3e-14 51.4 46.9 8.5e-07 28.2 3.1 3.5 3 1 1 4 4 4 3 Major Facilitator Superfamily OATP PF03137.20 CDJ48812.1 - 0.00045 18.6 0.1 0.00099 17.5 0.0 1.5 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CDJ48812.1 - 0.0042 16.0 0.0 1 8.1 0.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Pex14_N PF04695.13 CDJ48812.1 - 0.0043 17.7 2.0 0.0043 17.7 2.0 4.3 3 2 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF755 PF05501.11 CDJ48812.1 - 0.016 15.5 1.0 0.016 15.5 1.0 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF755) Kinesin PF00225.23 CDJ48813.1 - 0.018 13.9 0.0 0.018 13.9 0.0 3.2 2 1 0 3 3 3 0 Kinesin motor domain SART-1 PF03343.13 CDJ48813.1 - 1.5 7.3 26.8 0.041 12.4 17.2 2.1 2 0 0 2 2 2 0 SART-1 family BIV_Env PF05858.12 CDJ48813.1 - 6.1 4.9 4.8 1.5 6.9 0.6 1.8 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) Med15 PF09606.10 CDJ48813.1 - 7 5.2 84.6 0.24 10.0 13.9 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1003 PF06210.11 CDJ48814.1 - 0.13 12.4 0.5 0.24 11.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Spt20 PF12090.8 CDJ48815.1 - 0.11 12.1 22.7 0.12 12.0 22.7 1.3 1 0 0 1 1 1 0 Spt20 family Coilin_N PF15862.5 CDJ48815.1 - 0.19 11.5 9.7 0.2 11.5 9.7 1.2 1 0 0 1 1 1 0 Coilin N-terminus Robl_LC7 PF03259.17 CDJ48815.1 - 0.87 9.4 7.4 0.15 11.9 3.2 1.8 1 1 1 2 2 2 0 Roadblock/LC7 domain Dehydrin PF00257.19 CDJ48815.1 - 1.2 9.7 12.4 1.3 9.5 12.4 1.1 1 0 0 1 1 1 0 Dehydrin Pex14_N PF04695.13 CDJ48815.1 - 3.8 8.2 21.0 4.4 8.0 21.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM199X PF15814.5 CDJ48815.1 - 5.3 6.0 15.0 5.9 5.9 15.0 1.0 1 0 0 1 1 1 0 Protein family FAM199X DDHD PF02862.17 CDJ48815.1 - 8.7 6.4 11.4 9.5 6.3 11.4 1.1 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 CDJ48815.1 - 9.2 6.1 31.9 10 6.0 31.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ48815.1 - 10 6.1 6.7 11 6.0 6.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PolyA_pol PF01743.20 CDJ48816.1 - 7.4e-08 32.9 0.4 3.9e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Poly A polymerase head domain Vfa1 PF08432.10 CDJ48816.1 - 0.068 13.5 0.3 0.068 13.5 0.3 2.8 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Pkinase_fungal PF17667.1 CDJ48816.1 - 0.11 11.2 4.6 3.5 6.3 0.4 2.4 2 0 0 2 2 2 0 Fungal protein kinase SPX PF03105.19 CDJ48816.1 - 0.18 11.7 29.6 0.16 11.9 2.4 3.1 3 0 0 3 3 3 0 SPX domain MDM31_MDM32 PF08118.11 CDJ48816.1 - 0.39 9.3 3.4 0.2 10.3 0.6 1.9 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins Activator_LAG-3 PF11498.8 CDJ48816.1 - 0.51 9.2 34.9 0.67 8.9 24.8 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF4667 PF15700.5 CDJ48816.1 - 0.75 9.9 0.0 0.35 10.9 1.8 3.7 3 1 0 3 3 2 0 Domain of unknown function (DUF4667) Apt1 PF10351.9 CDJ48816.1 - 1.6 7.5 24.9 0.24 10.2 12.2 3.0 3 0 0 3 3 3 0 Golgi-body localisation protein domain DUF2052 PF09747.9 CDJ48816.1 - 2.7 8.1 12.7 0.26 11.4 3.4 2.9 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) SpoIIP PF07454.11 CDJ48816.1 - 5.9 6.3 16.2 7.4 5.9 6.4 3.3 3 1 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) FAM91_C PF14648.6 CDJ48816.1 - 8.2 5.1 9.1 2.2 7.0 0.1 2.5 3 0 0 3 3 3 0 FAM91 C-terminus TFIIA PF03153.13 CDJ48817.1 - 0.00088 19.4 26.0 0.00088 19.4 26.0 3.7 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit DUF4342 PF14242.6 CDJ48817.1 - 0.007 16.3 0.0 0.007 16.3 0.0 6.4 9 0 0 9 9 9 1 Domain of unknown function (DUF4342) OATP PF03137.20 CDJ48817.1 - 0.38 9.0 2.4 0.63 8.3 2.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family HCO3_cotransp PF00955.21 CDJ48817.1 - 1.4 7.7 3.3 2.5 6.8 3.3 1.3 1 0 0 1 1 1 0 HCO3- transporter family CSG2 PF16965.5 CDJ48817.1 - 2.1 7.2 5.0 4.2 6.2 5.0 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator Serinc PF03348.15 CDJ48817.1 - 3.8 6.3 6.1 10 4.9 6.1 1.6 1 0 0 1 1 1 0 Serine incorporator (Serinc) Velvet PF11754.8 CDJ48817.1 - 8.2 6.3 16.6 0.055 13.4 1.0 2.8 3 0 0 3 3 3 0 Velvet factor Wzy_C_2 PF11846.8 CDJ48819.1 - 0.0021 18.0 9.3 0.0027 17.6 9.3 1.2 1 0 0 1 1 1 1 Virulence factor membrane-bound polymerase, C-terminal Neuraminidase PF18413.1 CDJ48819.1 - 0.028 14.1 0.8 0.044 13.4 0.8 1.3 1 0 0 1 1 1 0 Neuraminidase-like domain Connexin PF00029.19 CDJ48819.1 - 0.043 13.6 3.9 0.056 13.2 3.9 1.1 1 0 0 1 1 1 0 Connexin DUF4834 PF16118.5 CDJ48819.1 - 0.066 14.2 4.3 0.12 13.4 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Band_3_cyto PF07565.13 CDJ48819.1 - 0.14 12.0 3.2 0.15 11.9 3.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SID-1_RNA_chan PF13965.6 CDJ48819.1 - 0.28 9.6 2.8 0.27 9.6 2.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spt20 PF12090.8 CDJ48819.1 - 0.88 9.1 14.8 1.1 8.8 14.8 1.1 1 0 0 1 1 1 0 Spt20 family FPN1 PF06963.12 CDJ48819.1 - 0.9 8.0 12.4 0.26 9.8 9.2 1.5 1 1 1 2 2 2 0 Ferroportin1 (FPN1) DDHD PF02862.17 CDJ48819.1 - 1.2 9.3 9.4 1.5 9.0 9.4 1.2 1 0 0 1 1 1 0 DDHD domain Tmemb_9 PF05434.11 CDJ48819.1 - 1.5 8.7 5.5 2.1 8.3 5.5 1.2 1 0 0 1 1 1 0 TMEM9 TFIIA PF03153.13 CDJ48819.1 - 3.8 7.4 24.7 4.3 7.2 24.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.15 CDJ48819.1 - 5.3 5.8 8.6 6 5.7 8.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3357 PF11837.8 CDJ48819.1 - 6.1 7.4 18.4 1.7 9.1 14.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Ctr PF04145.15 CDJ48819.1 - 7.8 7.1 6.7 9.5 6.8 6.3 1.3 1 1 0 1 1 1 0 Ctr copper transporter family PAT1 PF09770.9 CDJ48820.1 - 0.0084 14.4 45.1 0.0093 14.3 45.1 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 CCSAP PF15748.5 CDJ48820.1 - 0.0093 16.2 37.1 0.013 15.7 37.1 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated DUF966 PF06136.13 CDJ48820.1 - 7.2 6.2 33.7 8.4 6.0 33.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SOBP PF15279.6 CDJ48820.1 - 7.6 7.0 30.3 9.1 6.8 30.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RskA PF10099.9 CDJ48821.1 - 0.00057 20.2 7.5 0.00061 20.1 7.5 1.0 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ48821.1 - 0.27 10.8 19.5 0.23 11.0 19.5 1.2 1 0 0 1 1 1 0 Spt20 family Spc7_N PF15402.6 CDJ48821.1 - 2.8 6.1 12.0 2.9 6.0 12.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 ARS2 PF04959.13 CDJ48822.1 - 0.00023 21.6 1.1 0.00023 21.6 1.1 2.5 1 1 1 2 2 1 1 Arsenite-resistance protein 2 DUF908 PF06012.12 CDJ48822.1 - 0.00036 20.1 2.7 0.00058 19.4 2.7 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) SR-25 PF10500.9 CDJ48822.1 - 0.00038 20.1 16.4 0.00067 19.3 16.4 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4187 PF13821.6 CDJ48822.1 - 0.00085 19.1 0.2 0.0021 17.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) AIP3 PF03915.13 CDJ48822.1 - 0.0018 17.4 0.9 0.0028 16.8 0.9 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 AF-4 PF05110.13 CDJ48822.1 - 0.0082 14.3 17.6 0.012 13.8 17.6 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein FAM176 PF14851.6 CDJ48822.1 - 0.012 15.3 1.4 0.012 15.3 1.4 1.8 2 0 0 2 2 1 0 FAM176 family DUF5427 PF10310.9 CDJ48822.1 - 0.016 14.2 11.3 0.029 13.4 11.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DNA_pol_phi PF04931.13 CDJ48822.1 - 0.024 12.8 3.6 0.035 12.2 3.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Macoilin PF09726.9 CDJ48822.1 - 0.026 13.1 7.1 0.04 12.5 7.1 1.3 1 0 0 1 1 1 0 Macoilin family Usp PF00582.26 CDJ48822.1 - 0.05 14.1 1.5 14 6.2 0.1 2.7 3 0 0 3 3 3 0 Universal stress protein family CDC45 PF02724.14 CDJ48822.1 - 0.098 10.9 5.4 0.14 10.4 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 CDJ48822.1 - 0.2 10.5 9.5 0.28 10.0 9.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Herpes_capsid PF06112.11 CDJ48822.1 - 0.22 11.6 11.7 0.42 10.7 11.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF1645 PF07816.11 CDJ48822.1 - 0.22 12.1 10.6 0.46 11.0 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Peptidase_S64 PF08192.11 CDJ48822.1 - 0.28 9.6 13.1 0.028 13.0 9.0 1.3 2 0 0 2 2 2 0 Peptidase family S64 DUF1180 PF06679.12 CDJ48822.1 - 0.3 11.5 1.3 0.58 10.6 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) zf-C2H2 PF00096.26 CDJ48822.1 - 0.38 11.3 5.6 1 10.0 5.6 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Menin PF05053.13 CDJ48822.1 - 0.45 8.8 7.0 0.59 8.4 7.0 1.1 1 0 0 1 1 1 0 Menin GREB1 PF15782.5 CDJ48822.1 - 0.59 7.2 11.3 0.78 6.8 11.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Paf1 PF03985.13 CDJ48822.1 - 0.69 8.9 12.0 1.3 7.9 12.0 1.4 1 0 0 1 1 1 0 Paf1 RAP1 PF07218.11 CDJ48822.1 - 1.3 7.2 7.2 1.7 6.9 7.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ndc1_Nup PF09531.10 CDJ48822.1 - 1.4 7.6 11.6 2.2 6.8 11.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 CDJ48822.1 - 1.7 8.5 12.6 2.7 7.8 12.6 1.3 1 0 0 1 1 1 0 SPX domain DUF4667 PF15700.5 CDJ48822.1 - 1.8 8.6 17.2 0.025 14.7 9.9 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4667) Plasmodium_Vir PF05795.11 CDJ48822.1 - 2.3 7.5 7.2 3.7 6.9 7.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4692 PF15763.5 CDJ48822.1 - 5.3 7.5 8.9 9.9 6.6 8.9 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) AMPKBI PF04739.15 CDJ48822.1 - 5.3 7.4 5.7 26 5.2 4.8 2.6 2 1 0 2 2 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain Sporozoite_P67 PF05642.11 CDJ48822.1 - 6.5 4.7 15.0 9.3 4.2 15.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Neur_chan_memb PF02932.16 CDJ48822.1 - 7.3 6.6 6.3 5.9 6.9 5.1 1.4 2 0 0 2 2 1 0 Neurotransmitter-gated ion-channel transmembrane region Lin-8 PF03353.15 CDJ48822.1 - 7.6 6.0 14.5 4.9 6.6 12.2 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist ALMT PF11744.8 CDJ48822.1 - 8.4 5.1 6.0 12 4.6 6.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4148 PF13663.6 CDJ48823.1 - 0.00036 20.7 2.6 0.34 11.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4148) K_channel_TID PF07941.11 CDJ48823.1 - 0.54 10.8 26.5 3.4 8.2 11.9 2.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain RRM_1 PF00076.22 CDJ48824.1 - 1.9e-25 88.5 0.0 7.6e-16 57.7 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ48824.1 - 0.19 11.9 0.0 1.5 9.0 0.0 2.4 3 0 0 3 3 3 0 RNA recognition motif RRM_occluded PF16842.5 CDJ48824.1 - 0.35 10.8 4.2 35 4.4 0.0 3.9 4 1 0 4 4 4 0 Occluded RNA-recognition motif CSTF2_hinge PF14327.6 CDJ48825.1 - 0.24 11.9 1.4 10 6.6 0.0 2.4 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 SPG4 PF17325.2 CDJ48825.1 - 0.53 11.4 4.5 7.1 7.8 0.4 2.9 1 1 2 3 3 3 0 Stationary phase protein 4 LPP PF04728.13 CDJ48825.1 - 1.8 9.0 7.6 0.87 10.0 1.4 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper CTU2 PF10288.9 CDJ48827.1 - 0.027 14.7 0.6 0.037 14.3 0.6 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 SUIM_assoc PF16619.5 CDJ48828.1 - 0.037 14.1 5.4 0.067 13.3 5.4 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Roughex PF06020.11 CDJ48828.1 - 0.063 12.4 2.8 0.1 11.7 2.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF2057 PF09829.9 CDJ48829.1 - 0.0071 16.5 6.3 0.012 15.8 6.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2057) TMIE PF16038.5 CDJ48829.1 - 0.6 10.0 3.3 1.1 9.1 3.3 1.5 1 1 0 1 1 1 0 TMIE protein DUF3138 PF11336.8 CDJ48829.1 - 4.5 5.8 11.8 5.9 5.4 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Pkinase PF00069.25 CDJ48830.1 - 3.7e-23 82.2 0.1 3.8e-22 78.9 0.1 2.8 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ48830.1 - 2.5e-10 40.1 0.0 7.2e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase SUIM_assoc PF16619.5 CDJ48830.1 - 0.0014 18.7 4.4 0.0014 18.7 4.4 8.4 3 2 2 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ48830.1 - 0.0097 16.2 5.7 0.0097 16.2 5.7 9.2 5 3 2 8 8 8 3 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ48832.1 - 0.0079 15.8 26.8 0.013 15.1 26.8 1.4 1 0 0 1 1 1 1 Spt20 family Pex14_N PF04695.13 CDJ48832.1 - 0.6 10.7 24.0 2.1 9.0 21.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF908 PF06012.12 CDJ48832.1 - 2.2 7.6 7.5 2.4 7.5 7.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Lin-8 PF03353.15 CDJ48832.1 - 3.5 7.1 8.3 4 6.9 8.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ndc1_Nup PF09531.10 CDJ48832.1 - 8.7 4.9 12.3 10 4.7 12.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NST1 PF13945.6 CDJ48832.1 - 9.4 6.3 13.5 16 5.5 13.2 1.6 1 1 0 1 1 1 0 Salt tolerance down-regulator FHIPEP PF00771.20 CDJ48833.1 - 0.81 8.1 8.6 0.99 7.8 8.6 1.1 1 0 0 1 1 1 0 FHIPEP family PAT1 PF09770.9 CDJ48833.1 - 3.1 5.9 33.2 3.8 5.7 33.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chromo PF00385.24 CDJ48834.1 - 7.2e-24 83.4 0.0 1.1e-10 41.2 0.0 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CDJ48834.1 - 4.4e-11 43.0 0.0 7.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ48834.1 - 0.016 14.9 1.3 0.43 10.4 0.1 2.7 2 0 0 2 2 2 0 Integrase core domain Tyosinase_C PF18132.1 CDJ48834.1 - 0.1 13.2 0.0 26 5.5 0.0 2.9 3 0 0 3 3 3 0 Tyosinase C-terminal domain Fe_dep_repr_C PF02742.15 CDJ48834.1 - 0.12 12.5 1.4 5.2 7.2 0.3 3.1 2 1 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain RT_RNaseH_2 PF17919.1 CDJ48835.1 - 5.5e-28 96.9 0.1 1e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ48835.1 - 2.6e-26 92.0 0.0 5e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDJ48835.1 - 8.6e-17 61.0 2.0 2.5e-16 59.5 2.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDJ48835.1 - 8.9e-15 54.9 0.1 3.3e-14 53.1 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ48835.1 - 0.0002 21.5 0.4 0.00047 20.3 0.4 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Acyltransferase PF01553.21 CDJ48836.1 - 6e-08 32.4 0.1 0.00017 21.2 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase DUF4834 PF16118.5 CDJ48836.1 - 0.79 10.7 41.2 0.33 12.0 3.8 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) RR_TM4-6 PF06459.12 CDJ48837.1 - 0.00029 20.8 24.9 0.00032 20.6 24.9 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ48837.1 - 0.0031 16.3 29.4 0.0032 16.3 29.4 1.1 1 0 0 1 1 1 1 Presenilin Velvet PF11754.8 CDJ48837.1 - 0.01 15.8 20.3 0.012 15.6 20.3 1.3 1 0 0 1 1 1 0 Velvet factor AAA_11 PF13086.6 CDJ48837.1 - 0.013 15.3 21.2 0.015 15.1 21.2 1.1 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 CDJ48837.1 - 0.029 13.4 25.8 0.027 13.5 25.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF2828 PF11443.8 CDJ48837.1 - 0.059 11.5 20.3 0.068 11.3 20.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.16 CDJ48837.1 - 0.1 12.7 21.5 0.13 12.3 21.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sec62 PF03839.16 CDJ48837.1 - 0.13 11.8 22.6 0.14 11.6 22.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Raftlin PF15250.6 CDJ48837.1 - 0.15 10.8 21.7 0.15 10.8 21.7 1.0 1 0 0 1 1 1 0 Raftlin Otopetrin PF03189.13 CDJ48837.1 - 0.19 10.5 12.7 0.23 10.2 12.7 1.1 1 0 0 1 1 1 0 Otopetrin DUF913 PF06025.12 CDJ48837.1 - 0.21 10.6 14.9 0.29 10.1 14.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) LAP1C PF05609.12 CDJ48837.1 - 0.37 9.8 27.6 0.4 9.7 27.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) HCO3_cotransp PF00955.21 CDJ48837.1 - 0.52 9.1 11.4 0.68 8.7 11.4 1.2 1 0 0 1 1 1 0 HCO3- transporter family CDC45 PF02724.14 CDJ48837.1 - 0.65 8.2 25.4 0.73 8.1 25.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Pkinase_fungal PF17667.1 CDJ48837.1 - 0.97 8.1 12.0 0.99 8.1 12.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase SAGA-Tad1 PF12767.7 CDJ48837.1 - 1.1 8.9 21.9 1.2 8.8 21.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit LMBR1 PF04791.16 CDJ48837.1 - 1.2 8.0 14.3 1.4 7.7 14.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ALMT PF11744.8 CDJ48837.1 - 1.2 7.9 22.6 1.4 7.7 22.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter GREB1 PF15782.5 CDJ48837.1 - 1.4 5.9 27.6 1.4 5.9 27.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2151 PF10221.9 CDJ48837.1 - 1.8 7.1 15.5 1.9 7.0 15.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Membralin PF09746.9 CDJ48837.1 - 1.8 7.5 17.5 2 7.4 17.5 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF4045 PF13254.6 CDJ48837.1 - 1.8 8.1 31.1 1.9 8.0 31.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM60A PF15396.6 CDJ48837.1 - 1.9 8.4 26.6 2.4 8.1 26.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hamartin PF04388.12 CDJ48837.1 - 2 7.0 24.1 1.9 7.1 24.1 1.0 1 0 0 1 1 1 0 Hamartin protein PAT1 PF09770.9 CDJ48837.1 - 2.1 6.5 51.1 2.4 6.3 51.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FUSC PF04632.12 CDJ48837.1 - 2.3 6.7 12.5 2.8 6.4 12.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Endostatin PF06482.11 CDJ48837.1 - 2.5 7.5 29.4 3 7.2 29.4 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PA26 PF04636.13 CDJ48837.1 - 2.7 6.8 20.9 2.8 6.7 20.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) BAF1_ABF1 PF04684.13 CDJ48837.1 - 2.8 6.9 24.9 3.2 6.7 24.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ndc1_Nup PF09531.10 CDJ48837.1 - 4 6.0 28.6 4.9 5.7 28.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NPR3 PF03666.13 CDJ48837.1 - 4 6.1 30.7 4.3 6.0 30.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MTBP_C PF14920.6 CDJ48837.1 - 4.3 7.0 22.8 5.1 6.8 22.8 1.1 1 0 0 1 1 1 0 MDM2-binding MDFI PF15316.6 CDJ48837.1 - 5.1 7.2 17.3 6.6 6.8 17.3 1.3 1 0 0 1 1 1 0 MyoD family inhibitor ASC PF00858.24 CDJ48837.1 - 6.5 5.6 15.7 7.9 5.3 15.7 1.3 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel GET2 PF08690.10 CDJ48837.1 - 8.5 6.0 30.1 13 5.4 30.1 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Lin-8 PF03353.15 CDJ48837.1 - 9.2 5.7 39.0 11 5.4 39.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ketoacyl-synt PF00109.26 CDJ48838.1 - 7.3e-24 84.7 12.1 4e-12 46.2 0.2 3.6 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CDJ48838.1 - 1e-22 80.4 13.6 3.7e-15 56.0 0.1 3.8 3 1 0 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain T5orf172 PF10544.9 CDJ48838.1 - 0.2 12.2 1.7 0.58 10.7 0.1 2.6 2 0 0 2 2 2 0 T5orf172 domain AARP2CN PF08142.12 CDJ48838.1 - 0.75 9.9 3.7 3.9 7.6 0.0 3.1 3 0 0 3 3 3 0 AARP2CN (NUC121) domain Spt20 PF12090.8 CDJ48838.1 - 2.6 7.6 69.9 0.52 9.9 0.8 6.6 6 0 0 6 6 6 0 Spt20 family Macoilin PF09726.9 CDJ48839.1 - 2.3 6.7 14.6 2.7 6.4 14.6 1.1 1 0 0 1 1 1 0 Macoilin family PRAS PF15798.5 CDJ48839.1 - 2.5 8.7 11.8 4.2 8.0 3.2 2.3 1 1 1 2 2 2 0 Proline-rich AKT1 substrate 1 Lin-8 PF03353.15 CDJ48839.1 - 3.8 7.0 8.1 5.3 6.5 8.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ48839.1 - 7.7 5.2 12.2 9.5 4.9 12.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2722 PF10846.8 CDJ48840.1 - 3.7e-05 22.9 0.5 3.7e-05 22.9 0.5 8.9 6 2 1 7 7 7 2 Protein of unknown function (DUF2722) Trp_oprn_chp PF09534.10 CDJ48840.1 - 7.3e-05 22.6 8.0 7.3e-05 22.6 8.0 11.1 6 3 5 11 11 11 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Spt20 PF12090.8 CDJ48840.1 - 0.00051 19.7 7.4 0.00051 19.7 7.4 7.5 4 1 2 6 6 6 1 Spt20 family AF-4 PF05110.13 CDJ48840.1 - 0.00052 18.3 11.7 0.00052 18.3 11.7 6.7 6 2 0 7 7 7 1 AF-4 proto-oncoprotein INSIG PF07281.12 CDJ48840.1 - 0.076 12.6 0.1 0.076 12.6 0.1 4.5 5 1 0 5 5 5 0 Insulin-induced protein (INSIG) MarC PF01914.17 CDJ48840.1 - 0.34 10.3 0.0 0.34 10.3 0.0 2.6 3 0 0 3 3 3 0 MarC family integral membrane protein NPR3 PF03666.13 CDJ48841.1 - 1 8.1 36.3 1.2 7.9 36.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 CDJ48841.1 - 4.2 7.1 38.1 4.8 6.9 38.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 CDJ48843.1 - 2.7e-05 24.4 19.8 3.2e-05 24.1 19.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TPR_2 PF07719.17 CDJ48843.1 - 0.00015 21.6 10.0 0.018 15.1 0.8 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ48843.1 - 0.00064 19.3 0.0 0.00064 19.3 0.0 2.2 2 1 1 3 3 2 1 TPR repeat TPR_8 PF13181.6 CDJ48843.1 - 0.00066 19.7 0.1 0.019 15.1 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2232 PF09991.9 CDJ48843.1 - 0.001 18.3 0.7 0.0015 17.8 0.7 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) TPR_14 PF13428.6 CDJ48843.1 - 0.0011 19.6 10.0 0.017 15.9 0.2 5.7 3 2 2 5 5 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ48843.1 - 0.0014 18.7 4.3 0.0014 18.7 4.3 3.1 3 1 0 3 3 1 1 Tetratricopeptide repeat Spt20 PF12090.8 CDJ48843.1 - 0.0028 17.3 19.9 0.0049 16.5 19.9 1.4 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ48843.1 - 0.0058 15.6 13.1 0.0085 15.1 13.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ48843.1 - 0.017 13.9 4.0 0.018 13.8 4.0 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ48843.1 - 0.019 13.2 10.9 0.023 13.0 10.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPR_1 PF00515.28 CDJ48843.1 - 0.025 14.4 2.6 0.68 9.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DDHD PF02862.17 CDJ48843.1 - 0.027 14.6 1.4 0.036 14.2 1.4 1.2 1 0 0 1 1 1 0 DDHD domain DUF1980 PF09323.10 CDJ48843.1 - 0.06 13.3 0.9 0.094 12.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) eIF-3_zeta PF05091.12 CDJ48843.1 - 0.088 11.8 7.3 0.12 11.4 7.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med15 PF09606.10 CDJ48843.1 - 0.12 11.1 28.9 0.17 10.5 28.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GET2 PF08690.10 CDJ48843.1 - 0.14 11.8 6.4 0.2 11.3 6.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Neur_chan_memb PF02932.16 CDJ48843.1 - 0.17 11.9 1.2 0.22 11.6 1.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ48843.1 - 0.24 11.3 8.5 0.55 10.2 8.4 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 CDJ48843.1 - 0.29 11.8 22.2 0.85 10.3 22.1 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5427 PF10310.9 CDJ48843.1 - 0.49 9.3 19.1 0.84 8.5 19.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Connexin PF00029.19 CDJ48843.1 - 0.57 9.9 2.1 0.87 9.3 2.1 1.2 1 0 0 1 1 1 0 Connexin BRF1 PF07741.13 CDJ48843.1 - 0.72 10.2 9.4 1.7 9.1 8.9 1.9 2 0 0 2 2 1 0 Brf1-like TBP-binding domain Ndc1_Nup PF09531.10 CDJ48843.1 - 0.9 8.2 3.7 1 7.9 3.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SpoIIP PF07454.11 CDJ48843.1 - 0.97 8.8 6.7 1.4 8.3 6.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NARP1 PF12569.8 CDJ48843.1 - 1.1 8.1 11.9 9.9 4.9 8.5 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 CDJ48843.1 - 1.2 8.9 6.6 1.7 8.4 6.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TERB2 PF15101.6 CDJ48843.1 - 4.2 7.4 11.3 6.4 6.8 11.3 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 V_ATPase_I PF01496.19 CDJ48843.1 - 7.3 4.4 7.2 9.7 4.0 7.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0560 PF10577.9 CDJ48843.1 - 8.1 4.8 16.6 11 4.4 16.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Fibrillarin PF01269.17 CDJ48844.1 - 2.2e-101 337.7 0.0 4.1e-101 336.8 0.0 1.4 1 0 0 1 1 1 1 Fibrillarin Macoilin PF09726.9 CDJ48844.1 - 0.0011 17.7 14.8 0.0016 17.1 14.8 1.2 1 0 0 1 1 1 1 Macoilin family GCD14 PF08704.10 CDJ48844.1 - 0.0045 16.7 0.0 0.0045 16.7 0.0 3.3 3 1 0 3 3 2 1 tRNA methyltransferase complex GCD14 subunit SPX PF03105.19 CDJ48844.1 - 0.064 13.2 11.8 0.2 11.5 0.3 2.1 2 0 0 2 2 2 0 SPX domain CFIA_Pcf11 PF11526.8 CDJ48844.1 - 1.2 9.7 19.9 3.3 8.3 0.7 3.4 3 0 0 3 3 3 0 Subunit of cleavage factor IA Pcf11 Apt1 PF10351.9 CDJ48844.1 - 1.3 7.8 16.3 1.9 7.3 0.3 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ferlin_C PF16165.5 CDJ48844.1 - 2 8.3 6.1 0.47 10.4 0.6 2.5 3 0 0 3 3 3 0 Ferlin C-terminus PAT1 PF09770.9 CDJ48844.1 - 2.1 6.5 21.8 3.3 5.8 21.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tmemb_161AB PF10268.9 CDJ48844.1 - 2.4 6.7 4.1 4.7 5.8 4.1 1.5 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB DUF4834 PF16118.5 CDJ48844.1 - 2.6 9.1 24.8 3.2 8.8 2.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF45 PF01863.17 CDJ48844.1 - 5.4 7.0 10.8 9.5 6.2 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 Neur_chan_memb PF02932.16 CDJ48844.1 - 8 6.4 13.8 20 5.2 8.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Hamartin PF04388.12 CDJ48845.1 - 0.00038 19.3 40.7 0.00038 19.3 40.7 1.9 2 0 0 2 2 2 1 Hamartin protein FA_desaturase PF00487.24 CDJ48845.1 - 0.21 11.4 1.3 0.47 10.2 1.3 1.6 1 0 0 1 1 1 0 Fatty acid desaturase AP2 PF00847.20 CDJ48845.1 - 0.54 10.5 0.0 0.54 10.5 0.0 3.6 4 0 0 4 4 4 0 AP2 domain Ribosomal_L18 PF17135.4 CDJ48846.1 - 7.5e-69 230.9 0.2 8.9e-69 230.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CDJ48846.1 - 0.0016 19.2 0.0 0.0031 18.2 0.0 1.6 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DDRGK PF09756.9 CDJ48847.1 - 0.82 9.2 11.6 0.92 9.1 11.6 1.1 1 0 0 1 1 1 0 DDRGK domain XRN_N PF03159.18 CDJ48847.1 - 1.7 8.0 9.0 1.8 7.9 9.0 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus SR-25 PF10500.9 CDJ48847.1 - 1.8 8.1 41.4 2.6 7.6 41.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ48847.1 - 4.4 7.2 30.1 4.7 7.1 30.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ48847.1 - 7.2 5.0 29.5 7.8 4.9 29.5 1.0 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 CDJ48847.1 - 7.3 5.8 13.8 7.9 5.7 13.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lin-8 PF03353.15 CDJ48847.1 - 8.3 5.9 25.1 9.1 5.7 25.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4746 PF15928.5 CDJ48847.1 - 8.9 5.6 8.4 9.7 5.5 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SR-25 PF10500.9 CDJ48848.1 - 3.4e-08 33.4 45.4 3.3e-06 26.9 25.7 4.2 3 1 1 4 4 4 3 Nuclear RNA-splicing-associated protein Caldesmon PF02029.15 CDJ48848.1 - 3.2 6.4 61.4 1.2 7.8 26.2 2.2 2 0 0 2 2 2 0 Caldesmon Dicty_REP PF05086.12 CDJ48849.1 - 2.9 5.8 14.9 3.2 5.6 14.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein V_ATPase_I PF01496.19 CDJ48849.1 - 3.4 5.5 19.4 3.7 5.3 19.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 CDJ48849.1 - 4.2 5.8 21.5 6.7 5.1 21.5 1.3 1 0 0 1 1 1 0 Macoilin family Membralin PF09746.9 CDJ48849.1 - 8.5 5.3 14.7 9.1 5.2 14.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein Tic110 PF16940.5 CDJ48851.1 - 0.76 8.2 7.7 1 7.8 7.7 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter FAM199X PF15814.5 CDJ48852.1 - 0.66 9.0 30.4 0.77 8.8 30.4 1.1 1 0 0 1 1 1 0 Protein family FAM199X CCSAP PF15748.5 CDJ48852.1 - 1 9.5 36.5 1.2 9.2 36.5 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ48852.1 - 1.4 8.7 28.5 1.5 8.6 28.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 CDJ48852.1 - 2.2 7.6 18.1 2 7.7 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NARP1 PF12569.8 CDJ48852.1 - 2.2 7.1 18.6 2.1 7.2 18.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2828 PF11443.8 CDJ48852.1 - 2.5 6.1 17.9 2.5 6.1 17.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Velvet PF11754.8 CDJ48852.1 - 3.2 7.6 28.2 4.4 7.2 28.2 1.3 1 0 0 1 1 1 0 Velvet factor TCP PF03634.13 CDJ48852.1 - 3.5 8.2 33.7 4.5 7.8 33.7 1.1 1 0 0 1 1 1 0 TCP family transcription factor SprA-related PF12118.8 CDJ48852.1 - 4.5 6.3 43.1 5.2 6.1 43.1 1.1 1 0 0 1 1 1 0 SprA-related family NPR3 PF03666.13 CDJ48852.1 - 5.7 5.6 33.0 6.8 5.4 33.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5427 PF10310.9 CDJ48852.1 - 5.9 5.7 31.3 7.1 5.5 31.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) eIF-3_zeta PF05091.12 CDJ48852.1 - 8.8 5.2 29.5 8.9 5.2 29.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Endostatin PF06482.11 CDJ48852.1 - 8.8 5.7 23.6 9.5 5.6 23.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PPP4R2 PF09184.11 CDJ48852.1 - 9 5.8 25.7 9.2 5.8 25.7 1.0 1 0 0 1 1 1 0 PPP4R2 RskA PF10099.9 CDJ48853.1 - 0.00032 21.0 11.5 0.00032 21.0 11.5 5.6 2 2 1 3 3 3 1 Anti-sigma-K factor rskA Pex14_N PF04695.13 CDJ48853.1 - 0.018 15.7 11.1 0.018 15.7 11.1 5.1 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.9 CDJ48854.1 - 0.00027 20.6 19.9 0.00027 20.6 19.9 9.9 6 2 4 10 10 10 3 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 CDJ48855.1 - 7.7e-19 68.1 0.3 2.4e-09 37.0 0.1 6.7 6 3 0 6 6 6 3 Protein kinase domain BAF1_ABF1 PF04684.13 CDJ48855.1 - 1.6e-08 34.1 5.3 1.6e-08 34.1 5.3 5.8 3 2 3 6 6 6 1 BAF1 / ABF1 chromatin reorganising factor Herpes_LMP1 PF05297.11 CDJ48855.1 - 5.2 6.2 6.5 14 4.7 6.5 1.6 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Pet20 PF08692.10 CDJ48855.1 - 5.8 7.6 0.0 5.8 7.6 0.0 8.5 4 3 0 6 6 6 0 Mitochondrial protein Pet20 SR-25 PF10500.9 CDJ48856.1 - 0.00012 21.7 34.8 0.00012 21.7 34.8 15.6 4 2 10 16 16 16 2 Nuclear RNA-splicing-associated protein TBCC PF07986.12 CDJ48857.1 - 2.7e-14 52.9 1.4 8.3e-14 51.3 1.4 1.9 1 0 0 1 1 1 1 Tubulin binding cofactor C RNA_pol_Rpc4 PF05132.14 CDJ48857.1 - 0.00053 20.4 3.5 0.00053 20.4 3.5 4.4 4 1 0 4 4 4 1 RNA polymerase III RPC4 DUF4746 PF15928.5 CDJ48857.1 - 0.00076 19.0 5.4 0.00076 19.0 5.4 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4746) MDMPI_N PF11716.8 CDJ48857.1 - 0.002 18.8 1.0 0.002 18.8 1.0 6.4 5 2 0 5 5 5 1 Mycothiol maleylpyruvate isomerase N-terminal domain RskA PF10099.9 CDJ48857.1 - 0.0027 18.0 11.4 0.0027 18.0 11.4 8.1 3 3 2 5 5 5 1 Anti-sigma-K factor rskA TCP PF03634.13 CDJ48857.1 - 0.0071 16.9 10.4 0.0071 16.9 10.4 3.7 3 1 1 4 4 4 1 TCP family transcription factor DUF3682 PF12446.8 CDJ48857.1 - 0.0094 16.4 8.8 0.0094 16.4 8.8 8.4 6 2 2 8 8 8 1 Protein of unknown function (DUF3682) DUF913 PF06025.12 CDJ48857.1 - 0.22 10.5 15.1 0.046 12.7 6.1 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.6 CDJ48857.1 - 0.62 8.4 6.6 0.31 9.4 3.6 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 CDJ48857.1 - 4.1 5.2 29.6 0.098 10.6 17.3 2.7 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family zf-CCCH PF00642.24 CDJ48858.1 - 9.2e-08 31.8 6.6 9.2e-08 31.8 6.6 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 CDJ48858.1 - 6.1e-06 26.1 12.8 6.1e-06 26.1 12.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ48858.1 - 6.1e-05 22.8 12.0 0.00019 21.2 12.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ48858.1 - 0.00041 20.1 11.1 0.00041 20.1 11.1 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ48858.1 - 0.0017 18.2 11.6 0.041 13.7 11.6 2.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 NOA36 PF06524.12 CDJ48858.1 - 0.0032 16.9 20.7 0.0032 16.9 20.7 2.1 1 1 1 2 2 2 1 NOA36 protein zf-rbx1 PF12678.7 CDJ48858.1 - 0.0034 17.7 9.3 0.009 16.3 9.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDJ48858.1 - 0.0046 17.3 12.4 0.0046 17.3 12.4 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_10 PF16685.5 CDJ48858.1 - 0.0073 16.4 7.2 0.0073 16.4 7.2 2.5 4 0 0 4 4 3 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 CDJ48858.1 - 0.015 15.2 13.8 0.047 13.6 13.8 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 CDJ48858.1 - 0.032 14.3 11.9 0.048 13.7 8.5 2.4 2 0 0 2 2 2 0 Zinc finger domain DUF755 PF05501.11 CDJ48858.1 - 0.059 13.6 14.4 0.22 11.8 6.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) zf-RING_UBOX PF13445.6 CDJ48858.1 - 0.12 12.5 7.8 0.28 11.2 7.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PolC_DP2 PF03833.13 CDJ48858.1 - 0.22 9.3 8.2 0.34 8.7 8.2 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 RNA_pol_3_Rpc31 PF11705.8 CDJ48858.1 - 0.67 10.2 26.3 0.19 12.0 13.7 2.7 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 IBN_N PF03810.19 CDJ48859.1 - 1.4e-13 50.6 0.1 3.2e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF383 PF04063.14 CDJ48859.1 - 0.041 13.5 0.4 0.058 13.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF383) Presenilin PF01080.17 CDJ48860.1 - 4.1 6.1 45.5 5.4 5.7 45.5 1.3 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ48862.1 - 0.05 13.2 19.9 0.082 12.5 9.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ48862.1 - 0.19 10.6 46.9 0.064 12.2 16.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) PRP1_N PF06424.12 CDJ48862.1 - 0.33 11.3 21.8 0.88 10.0 8.3 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal ArsP_2 PF11449.8 CDJ48862.1 - 0.9 8.7 5.6 0.35 10.0 0.3 2.0 2 0 0 2 2 2 0 Putative, 10TM heavy-metal exporter EPL1 PF10513.9 CDJ48862.1 - 1 9.7 26.1 0.66 10.3 7.3 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like PTPRCAP PF15713.5 CDJ48862.1 - 1.8 8.8 30.4 2.2 8.6 14.6 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated SpoIIP PF07454.11 CDJ48862.1 - 1.9 7.9 25.1 0.63 9.5 9.5 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TCP PF03634.13 CDJ48862.1 - 2.3 8.8 25.5 2.4 8.7 11.0 2.3 2 0 0 2 2 2 0 TCP family transcription factor MAJIN PF15077.6 CDJ48862.1 - 3.1 7.5 26.8 0.083 12.7 7.5 2.1 2 0 0 2 2 2 0 Membrane-anchored junction protein FAM60A PF15396.6 CDJ48862.1 - 4.6 7.2 17.7 4.5 7.2 5.3 2.1 2 0 0 2 2 2 0 Protein Family FAM60A EFTUD2 PF16004.5 CDJ48862.1 - 5.3 7.6 25.3 2.6 8.7 8.4 2.2 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus CTNNB1_binding PF08347.11 CDJ48862.1 - 5.5 7.1 21.6 2.9 8.0 4.3 2.1 2 0 0 2 2 2 0 N-terminal CTNNB1 binding Connexin PF00029.19 CDJ48862.1 - 7.3 6.3 21.0 2.7 7.7 5.9 2.1 2 0 0 2 2 2 0 Connexin CPSF100_C PF13299.6 CDJ48862.1 - 8.6 6.5 26.7 9 6.4 13.9 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Eapp_C PF10238.9 CDJ48862.1 - 8.8 6.4 25.0 0.91 9.6 6.2 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein LMBR1 PF04791.16 CDJ48863.1 - 0.47 9.3 9.9 0.61 8.9 9.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein KdgT PF03812.13 CDJ48863.1 - 0.8 9.0 6.6 2.1 7.6 7.2 1.4 2 0 0 2 2 2 0 2-keto-3-deoxygluconate permease OAD_gamma PF04277.13 CDJ48863.1 - 1.1 9.9 13.4 1 10.0 3.0 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain YfhO PF09586.10 CDJ48863.1 - 2 6.5 10.5 2.7 6.1 10.5 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Hamartin PF04388.12 CDJ48863.1 - 2.6 6.6 44.5 3 6.4 44.5 1.1 1 0 0 1 1 1 0 Hamartin protein DUF4603 PF15376.6 CDJ48865.1 - 0.92 6.8 4.7 1.5 6.1 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Baculo_PEP_C PF04513.12 CDJ48865.1 - 9.2 6.3 7.1 1 9.4 0.7 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Otopetrin PF03189.13 CDJ48867.1 - 0.005 15.7 4.2 0.0076 15.1 0.1 2.3 2 0 0 2 2 2 1 Otopetrin Pex14_N PF04695.13 CDJ48867.1 - 0.016 15.8 17.1 0.016 15.8 17.1 8.8 3 1 2 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.22 CDJ48867.1 - 0.066 12.4 0.0 0.066 12.4 0.0 3.6 3 1 0 3 3 3 0 ZIP Zinc transporter DUF5385 PF17359.2 CDJ48868.1 - 2.4 7.6 21.9 2.7 7.5 21.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5385) TFIIA PF03153.13 CDJ48869.1 - 1.8 8.5 21.0 2.2 8.2 21.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.11 CDJ48869.1 - 9.3 4.2 10.2 12 3.9 10.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_B PF00136.21 CDJ48870.1 - 6.5e-25 87.7 0.1 1.1e-24 87.0 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CDJ48870.1 - 0.00019 20.7 0.0 0.00043 19.5 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DUF2722 PF10846.8 CDJ48870.1 - 0.002 17.1 2.9 0.002 17.1 2.9 5.1 4 2 0 4 4 4 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ48870.1 - 5.7 6.5 58.4 0.017 14.7 8.7 4.9 5 0 0 5 5 5 0 Spt20 family NPR3 PF03666.13 CDJ48871.1 - 0.28 9.9 18.9 0.33 9.7 18.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MCM_bind PF09739.9 CDJ48871.1 - 0.36 9.2 15.7 0.37 9.2 15.7 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Pex14_N PF04695.13 CDJ48871.1 - 0.41 11.3 26.2 0.58 10.8 26.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CSG2 PF16965.5 CDJ48871.1 - 0.43 9.5 5.9 0.48 9.3 5.9 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator EPL1 PF10513.9 CDJ48871.1 - 1.5 9.2 20.9 2.2 8.7 20.9 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Presenilin PF01080.17 CDJ48871.1 - 2.2 6.9 27.2 2.6 6.7 27.2 1.0 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ48871.1 - 2.3 6.4 32.6 2.5 6.2 32.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4569 PF15133.6 CDJ48871.1 - 2.6 7.7 20.4 2.8 7.6 20.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Endostatin PF06482.11 CDJ48871.1 - 3.1 7.2 18.1 3.4 7.0 18.1 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin RR_TM4-6 PF06459.12 CDJ48871.1 - 3.4 7.4 23.4 4.1 7.2 23.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ48871.1 - 3.5 6.5 11.1 3.9 6.4 11.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Afi1 PF07792.12 CDJ48871.1 - 3.6 8.1 17.1 4.9 7.6 17.1 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Gti1_Pac2 PF09729.9 CDJ48871.1 - 3.9 7.5 17.7 4.7 7.3 17.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family MAJIN PF15077.6 CDJ48871.1 - 4 7.2 18.0 4.6 7.0 18.0 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Neur_chan_memb PF02932.16 CDJ48871.1 - 4.3 7.3 17.1 4.8 7.2 17.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 CDJ48871.1 - 4.7 5.5 7.8 4.9 5.5 7.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 CDJ48871.1 - 5.4 5.9 21.7 5.9 5.8 21.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 BORG_CEP PF14957.6 CDJ48871.1 - 8.2 7.6 13.4 11 7.1 13.4 1.3 1 0 0 1 1 1 0 Cdc42 effector SelP_N PF04592.14 CDJ48871.1 - 9.6 5.5 25.7 11 5.3 25.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2828 PF11443.8 CDJ48871.1 - 9.6 4.2 20.3 11 4.0 20.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TFIIA PF03153.13 CDJ48872.1 - 0.0049 16.9 18.6 0.0049 16.9 18.6 6.6 5 1 0 6 6 6 3 Transcription factor IIA, alpha/beta subunit CLN3 PF02487.17 CDJ48872.1 - 0.058 12.4 3.3 0.084 11.9 1.2 2.1 2 0 0 2 2 2 0 CLN3 protein Mak_N_cap PF18085.1 CDJ48872.1 - 0.084 13.9 1.5 1.8 9.7 0.0 3.8 2 0 0 2 2 2 0 Maltokinase N-terminal cap domain IMUP PF15761.5 CDJ48872.1 - 7.1 7.4 40.0 0.84 10.4 6.5 5.4 4 0 0 4 4 4 0 Immortalisation up-regulated protein Spt20 PF12090.8 CDJ48873.1 - 0.13 11.9 16.9 0.2 11.2 16.9 1.2 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 CDJ48873.1 - 0.48 10.5 1.5 0.52 10.3 1.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF966 PF06136.13 CDJ48873.1 - 1.1 8.9 3.8 1.4 8.6 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) gag-asp_proteas PF13975.6 CDJ48874.1 - 0.039 14.5 0.0 0.1 13.1 0.0 1.7 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ48874.1 - 0.078 12.7 0.1 7.7 6.3 0.0 2.2 1 1 1 2 2 2 0 Retroviral aspartyl protease Glyco_transf_17 PF04724.13 CDJ48874.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 17 Asp_protease_2 PF13650.6 CDJ48874.1 - 0.19 12.4 0.0 0.42 11.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 CDJ48875.1 - 2.5e-17 63.1 0.0 4.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ48875.1 - 7.4e-13 48.5 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ48875.1 - 1.7e-07 31.2 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PH PF00169.29 CDJ48876.1 - 5.8e-12 46.0 0.0 2.4e-05 24.8 0.0 3.3 2 1 1 3 3 3 2 PH domain RskA PF10099.9 CDJ48877.1 - 0.0088 16.4 52.4 0.18 12.1 8.2 4.4 4 0 0 4 4 4 4 Anti-sigma-K factor rskA EphA2_TM PF14575.6 CDJ48877.1 - 7.7 7.5 8.5 1.3 10.0 1.6 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain PBP PF01161.20 CDJ48879.1 - 5.5e-06 26.7 0.0 8.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ecm29 PF13001.7 CDJ48880.1 - 5.1e-10 38.6 1.1 3e-05 22.9 0.7 2.7 2 0 0 2 2 2 2 Proteasome stabiliser Cohesin_HEAT PF12765.7 CDJ48880.1 - 0.023 15.0 0.1 0.46 10.8 0.1 2.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 CDJ48880.1 - 0.061 13.6 0.1 0.061 13.6 0.1 6.4 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 CDJ48880.1 - 0.14 12.7 0.0 0.14 12.7 0.0 10.0 11 0 0 11 11 11 0 HEAT-like repeat DTW PF03942.15 CDJ48881.1 - 9.8e-23 80.9 5.7 5.3e-22 78.5 5.7 2.2 1 1 0 1 1 1 1 DTW domain Spt20 PF12090.8 CDJ48881.1 - 0.025 14.2 12.2 0.55 9.8 0.1 2.3 2 0 0 2 2 2 0 Spt20 family Connexin PF00029.19 CDJ48881.1 - 0.39 10.5 2.4 1.1 9.0 0.5 2.2 2 0 0 2 2 2 0 Connexin Lin-8 PF03353.15 CDJ48881.1 - 2.4 7.6 7.4 0.39 10.2 1.4 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist EXS PF03124.14 CDJ48882.1 - 0.0074 15.7 0.8 0.009 15.4 0.8 1.1 1 0 0 1 1 1 1 EXS family TcpE PF12648.7 CDJ48882.1 - 0.015 15.8 1.4 0.025 15.1 1.4 1.4 1 0 0 1 1 1 0 TcpE family DUF21 PF01595.20 CDJ48882.1 - 0.03 14.0 2.0 0.034 13.8 1.2 1.5 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain DUF1700 PF08006.11 CDJ48882.1 - 0.036 13.6 0.4 0.053 13.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF92 PF01940.16 CDJ48882.1 - 0.036 13.5 2.7 0.05 13.0 2.7 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 DUF2207 PF09972.9 CDJ48882.1 - 0.67 8.7 2.1 0.93 8.2 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sdh_cyt PF01127.22 CDJ48882.1 - 3.6 7.6 8.5 5.4 7.1 8.5 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4179 PF13786.6 CDJ48884.1 - 1.1 9.8 3.9 10 6.6 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) SMYLE_N PF18615.1 CDJ48886.1 - 0.00088 18.9 12.7 0.00088 18.9 12.7 4.8 4 1 0 5 5 5 1 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF2207 PF09972.9 CDJ48886.1 - 0.01 14.6 0.2 0.047 12.5 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Peptidase_M56 PF05569.11 CDJ48886.1 - 0.74 8.9 3.5 2 7.5 1.8 2.4 2 0 0 2 2 2 0 BlaR1 peptidase M56 RRM_1 PF00076.22 CDJ48887.1 - 1.7e-17 63.0 0.0 2.5e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ48887.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif Glyoxalase_5 PF14696.6 CDJ48887.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal RRM_1 PF00076.22 CDJ48888.1 - 5.3e-09 35.8 0.0 6.7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RskA PF10099.9 CDJ48889.1 - 0.00013 22.4 15.2 0.00013 22.4 15.2 3.0 2 1 0 2 2 1 1 Anti-sigma-K factor rskA HemX PF04375.14 CDJ48889.1 - 0.0051 16.1 12.8 0.0051 16.1 12.8 2.2 3 0 0 3 3 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2722 PF10846.8 CDJ48889.1 - 0.0057 15.6 19.8 0.0057 15.6 19.8 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) DUF2828 PF11443.8 CDJ48889.1 - 0.0064 14.7 1.9 0.0089 14.2 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF3824 PF12868.7 CDJ48889.1 - 0.0067 17.1 4.6 0.0067 17.1 4.6 3.5 3 1 0 3 3 2 1 Domain of unknwon function (DUF3824) NST1 PF13945.6 CDJ48889.1 - 0.0089 16.2 8.1 0.0089 16.2 8.1 2.9 3 0 0 3 3 3 1 Salt tolerance down-regulator MAP65_ASE1 PF03999.12 CDJ48889.1 - 0.012 14.3 20.2 0.019 13.7 20.2 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4667 PF15700.5 CDJ48889.1 - 0.014 15.5 4.8 0.014 15.5 4.8 3.2 2 1 1 3 3 2 0 Domain of unknown function (DUF4667) FHIPEP PF00771.20 CDJ48889.1 - 0.023 13.2 1.7 0.04 12.4 1.7 1.3 1 0 0 1 1 1 0 FHIPEP family Trp_oprn_chp PF09534.10 CDJ48889.1 - 0.11 12.3 23.6 0.02 14.7 4.5 2.4 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RICTOR_N PF14664.6 CDJ48889.1 - 0.28 10.1 4.7 0.11 11.4 1.2 1.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Suf PF05843.14 CDJ48889.1 - 0.28 11.1 24.2 0.11 12.4 16.8 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ecl1 PF12855.7 CDJ48889.1 - 0.34 12.0 36.5 2 9.5 4.6 2.2 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins MecA PF05389.12 CDJ48889.1 - 0.54 9.9 5.4 0.29 10.7 2.3 1.9 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF1840 PF08895.11 CDJ48889.1 - 0.7 10.3 9.7 0.048 14.0 4.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) LCIB_C_CA PF18599.1 CDJ48889.1 - 0.76 9.0 6.1 1.5 8.1 6.1 1.4 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases CD20 PF04103.15 CDJ48889.1 - 1 9.5 8.0 3.7 7.6 0.4 3.1 2 1 1 3 3 3 0 CD20-like family Med24_N PF11277.8 CDJ48889.1 - 1 7.3 5.3 1.5 6.8 5.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal SLC12 PF03522.15 CDJ48889.1 - 1 8.3 7.8 0.84 8.6 5.5 1.8 2 0 0 2 2 2 0 Solute carrier family 12 SpoIIP PF07454.11 CDJ48889.1 - 2.1 7.7 8.8 0.25 10.7 3.7 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Band_3_cyto PF07565.13 CDJ48889.1 - 2.2 8.0 12.5 2.8 7.7 7.6 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Plasmodium_Vir PF05795.11 CDJ48889.1 - 2.9 7.2 12.4 1.1 8.6 7.6 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein LCD1 PF09798.9 CDJ48889.1 - 5.1 5.5 9.2 0.073 11.6 2.0 1.6 2 0 0 2 2 2 0 DNA damage checkpoint protein Orf78 PF06024.12 CDJ48889.1 - 5.7 7.3 7.9 5.8 7.3 2.6 2.8 3 0 0 3 3 3 0 Orf78 (ac78) AIF_C PF14721.6 CDJ48889.1 - 5.9 7.3 11.4 7.3 7.0 5.4 2.6 3 0 0 3 3 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EOS1 PF12326.8 CDJ48889.1 - 8.7 6.2 11.6 2.1 8.3 4.2 2.3 2 1 0 2 2 2 0 N-glycosylation protein G-patch PF01585.23 CDJ48890.1 - 7.7e-05 22.5 2.0 0.00021 21.1 2.0 1.7 1 0 0 1 1 1 1 G-patch domain SR-25 PF10500.9 CDJ48890.1 - 0.00051 19.7 16.0 0.00051 19.7 16.0 7.8 4 3 3 7 7 7 4 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ48890.1 - 0.0012 19.2 6.4 0.0012 19.2 6.4 8.8 4 3 3 7 7 7 4 Anti-sigma-K factor rskA CCSAP PF15748.5 CDJ48890.1 - 0.0013 18.9 6.1 0.0013 18.9 6.1 7.1 4 2 2 6 6 6 2 Centriole, cilia and spindle-associated ERM PF00769.19 CDJ48890.1 - 0.007 16.2 24.7 0.007 16.2 24.7 6.9 4 2 1 6 6 6 1 Ezrin/radixin/moesin family RPA43_OB PF17875.1 CDJ48890.1 - 0.1 13.2 0.1 0.1 13.2 0.1 7.9 7 2 0 7 7 7 0 RPA43 OB domain in RNA Pol I Utp14 PF04615.13 CDJ48890.1 - 0.28 9.7 88.0 0.01 14.5 22.7 3.4 2 1 1 3 3 3 0 Utp14 protein SR-25 PF10500.9 CDJ48891.1 - 0.00074 19.2 12.5 0.00074 19.2 12.5 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein MID_MedPIWI PF18296.1 CDJ48891.1 - 0.012 15.4 18.3 0.021 14.6 3.5 2.2 2 0 0 2 2 2 0 MID domain of medPIWI TFIIA PF03153.13 CDJ48891.1 - 0.015 15.4 58.3 0.15 12.0 36.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4050 PF13259.6 CDJ48891.1 - 0.024 14.9 10.6 0.52 10.6 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) DUF2126 PF09899.9 CDJ48891.1 - 0.037 12.1 7.9 0.0097 14.0 4.6 1.6 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) TCP PF03634.13 CDJ48891.1 - 0.097 13.2 20.2 0.11 13.1 3.3 2.2 2 0 0 2 2 2 0 TCP family transcription factor PAT1 PF09770.9 CDJ48891.1 - 0.38 9.0 25.6 0.091 11.0 12.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CPSF100_C PF13299.6 CDJ48891.1 - 1.3 9.2 15.5 9.9 6.3 0.2 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Neur_chan_memb PF02932.16 CDJ48891.1 - 3 7.8 12.7 4.9 7.1 4.9 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Tmp39 PF10271.9 CDJ48891.1 - 3.1 6.7 6.4 0.37 9.7 0.2 1.9 2 0 0 2 2 2 0 Putative transmembrane protein Suf PF05843.14 CDJ48891.1 - 3.7 7.4 23.8 0.83 9.6 10.9 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) CCSAP PF15748.5 CDJ48891.1 - 7 6.7 26.2 1.7 8.7 4.3 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF4228 PF14009.6 CDJ48891.1 - 8 6.8 14.0 0.94 9.8 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4228) AAA_12 PF13087.6 CDJ48892.1 - 9.2e-10 38.5 0.0 9.2e-10 38.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain DUF755 PF05501.11 CDJ48892.1 - 0.0036 17.6 22.0 0.0036 17.6 22.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ48892.1 - 0.018 14.6 26.8 0.11 12.1 20.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Herpes_LMP1 PF05297.11 CDJ48892.1 - 0.78 8.9 4.3 1.3 8.1 4.3 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) GREB1 PF15782.5 CDJ48892.1 - 1 6.4 24.6 1.7 5.7 24.6 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ48892.1 - 3 7.3 27.0 0.26 10.8 16.3 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist YABBY PF04690.13 CDJ48892.1 - 5.4 7.6 13.0 18 5.8 7.5 2.7 2 0 0 2 2 2 0 YABBY protein UPF1_Zn_bind PF09416.10 CDJ48896.1 - 6.7e-13 48.9 0.0 7.2e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) TFIIA PF03153.13 CDJ48897.1 - 0.12 12.3 32.7 0.14 12.1 32.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GAGA_bind PF06217.12 CDJ48897.1 - 0.32 11.3 13.7 0.38 11.0 13.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SOBP PF15279.6 CDJ48897.1 - 0.33 11.5 12.3 0.36 11.4 12.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein HAUS6_N PF14661.6 CDJ48897.1 - 0.63 9.6 17.1 0.78 9.3 17.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Exonuc_VII_L PF02601.15 CDJ48897.1 - 1.2 8.7 19.4 1.5 8.3 19.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Activator_LAG-3 PF11498.8 CDJ48897.1 - 1.3 7.9 31.7 1.7 7.5 31.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AAA_23 PF13476.6 CDJ48897.1 - 1.4 9.4 17.2 1.8 9.0 17.2 1.1 1 0 0 1 1 1 0 AAA domain RIFIN PF02009.16 CDJ48897.1 - 2.5 7.9 12.6 3.3 7.5 12.6 1.1 1 0 0 1 1 1 0 Rifin Peptidase_S64 PF08192.11 CDJ48897.1 - 6.7 5.1 15.4 7.2 5.0 15.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 ALG3 PF05208.13 CDJ48898.1 - 0.54 9.6 3.3 0.18 11.2 0.4 1.6 2 0 0 2 2 2 0 ALG3 protein Pkinase PF00069.25 CDJ48899.1 - 2.6e-21 76.2 0.0 4.1e-16 59.1 0.0 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ48899.1 - 9.6e-11 41.5 0.1 1.5e-07 31.0 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Otopetrin PF03189.13 CDJ48900.1 - 1.2 7.8 5.9 2.2 7.0 5.9 1.5 1 0 0 1 1 1 0 Otopetrin Paramyxo_ncap PF00973.19 CDJ48900.1 - 8.3 5.2 8.9 12 4.6 8.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein cNMP_binding PF00027.29 CDJ48901.1 - 4.7e-17 61.8 0.0 5.8e-09 35.9 0.0 3.7 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain RskA PF10099.9 CDJ48901.1 - 0.0043 17.4 0.0 0.0043 17.4 0.0 7.1 6 3 0 6 6 6 2 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ48901.1 - 0.02 15.0 20.8 0.38 10.8 1.8 4.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SOG2 PF10428.9 CDJ48902.1 - 2.7 7.1 8.4 4.3 6.4 8.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3458_C PF17432.2 CDJ48903.1 - 2.6e-96 322.8 9.0 3.8e-96 322.2 9.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 CDJ48903.1 - 2.6e-40 138.3 0.2 5.9e-40 137.2 0.2 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 CDJ48903.1 - 1.9e-23 82.7 0.1 4.6e-23 81.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 CDJ48903.1 - 1e-10 42.1 0.0 1.9e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 CDJ48903.1 - 0.089 13.2 0.3 1 9.8 0.3 2.4 1 1 1 2 2 2 0 M61 glycyl aminopeptidase ICL PF00463.21 CDJ48903.1 - 0.091 11.2 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Isocitrate lyase family zf-DNL PF05180.12 CDJ48904.1 - 4.4e-15 55.4 3.9 7.1e-15 54.7 3.9 1.3 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.18 CDJ48904.1 - 0.08 12.8 2.4 4.7 7.1 0.9 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DRMBL PF07522.14 CDJ48905.1 - 0.0026 17.9 0.0 0.0068 16.6 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 CDJ48905.1 - 0.021 14.8 0.1 0.052 13.5 0.1 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Methyltransf_11 PF08241.12 CDJ48906.1 - 6.5e-12 45.9 0.0 1.7e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ48906.1 - 1.9e-09 38.1 0.0 4.5e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ48906.1 - 6.9e-05 23.5 0.2 0.0006 20.5 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ48906.1 - 0.00011 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ48906.1 - 0.00028 20.7 0.0 0.00061 19.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF2956 PF11169.8 CDJ48906.1 - 0.049 13.8 4.0 0.1 12.8 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) NNMT_PNMT_TEMT PF01234.17 CDJ48906.1 - 0.14 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CDC45 PF02724.14 CDJ48906.1 - 8.3 4.6 6.8 12 4.1 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.22 CDJ48907.1 - 9.1e-14 51.0 0.1 1.5e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 CDJ48907.1 - 3e-11 43.4 0.0 1.2e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 SPOC domain RRM_occluded PF16842.5 CDJ48907.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif SET_assoc PF11767.8 CDJ48907.1 - 0.24 11.1 0.2 0.43 10.2 0.2 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Spt20 PF12090.8 CDJ48909.1 - 0.17 11.4 11.5 0.2 11.3 11.5 1.1 1 0 0 1 1 1 0 Spt20 family Menin PF05053.13 CDJ48909.1 - 1 7.7 11.5 1 7.6 11.5 1.0 1 0 0 1 1 1 0 Menin DLIC PF05783.11 CDJ48909.1 - 1.3 7.7 8.1 1.4 7.6 8.1 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SPX PF03105.19 CDJ48909.1 - 1.9 8.3 19.4 2 8.2 19.4 1.0 1 0 0 1 1 1 0 SPX domain DUF1180 PF06679.12 CDJ48909.1 - 2.9 8.3 10.9 3.2 8.1 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 CDJ48909.1 - 4.2 5.8 19.5 4.3 5.8 19.5 1.0 1 0 0 1 1 1 0 Macoilin family DUF4692 PF15763.5 CDJ48909.1 - 6.5 7.2 14.8 8.8 6.8 14.8 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Lin-8 PF03353.15 CDJ48909.1 - 9.2 5.7 11.3 9.6 5.7 11.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 CDJ48910.1 - 0.00021 20.2 26.0 0.00027 19.8 26.0 1.1 1 0 0 1 1 1 1 Presenilin SAGA-Tad1 PF12767.7 CDJ48910.1 - 0.0027 17.5 16.0 0.003 17.3 16.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Rgp1 PF08737.10 CDJ48910.1 - 0.0099 15.1 14.1 0.011 15.0 14.1 1.0 1 0 0 1 1 1 1 Rgp1 DUF4045 PF13254.6 CDJ48910.1 - 0.01 15.5 17.7 0.012 15.3 17.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hamartin PF04388.12 CDJ48910.1 - 0.062 12.0 21.3 0.074 11.7 21.3 1.0 1 0 0 1 1 1 0 Hamartin protein WTX PF09422.10 CDJ48910.1 - 0.082 12.0 14.4 0.1 11.6 14.4 1.2 1 0 0 1 1 1 0 WTX protein Ndc1_Nup PF09531.10 CDJ48910.1 - 0.088 11.5 20.4 0.099 11.3 20.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NPR3 PF03666.13 CDJ48910.1 - 0.13 11.0 22.8 0.16 10.7 22.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Lin-8 PF03353.15 CDJ48910.1 - 0.18 11.3 30.9 0.24 10.9 30.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Asp-B-Hydro_N PF05279.11 CDJ48910.1 - 0.23 11.5 16.6 0.3 11.1 16.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CCSAP PF15748.5 CDJ48910.1 - 0.34 11.1 30.5 0.4 10.8 30.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated LAP1C PF05609.12 CDJ48910.1 - 0.37 9.8 23.0 0.41 9.7 23.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Exonuc_VII_L PF02601.15 CDJ48910.1 - 0.43 10.1 26.7 0.52 9.8 26.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Membralin PF09746.9 CDJ48910.1 - 0.49 9.4 16.1 0.64 9.0 16.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein IHABP4_N PF16174.5 CDJ48910.1 - 0.6 10.7 34.0 1 10.0 34.0 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal RIFIN PF02009.16 CDJ48910.1 - 0.64 9.9 16.8 0.78 9.6 16.8 1.1 1 0 0 1 1 1 0 Rifin Dapper PF15268.6 CDJ48910.1 - 0.64 8.8 28.8 0.7 8.7 28.8 1.1 1 0 0 1 1 1 0 Dapper GAGA_bind PF06217.12 CDJ48910.1 - 0.69 10.1 20.9 0.8 9.9 20.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Zip PF02535.22 CDJ48910.1 - 0.9 8.7 19.1 1.4 8.1 19.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 CDJ48910.1 - 0.9 9.5 22.2 1.4 8.9 22.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.9 CDJ48910.1 - 1.1 7.5 51.7 1.3 7.2 51.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Raftlin PF15250.6 CDJ48910.1 - 1.1 7.9 21.2 1.4 7.6 21.2 1.0 1 0 0 1 1 1 0 Raftlin Vac7 PF12751.7 CDJ48910.1 - 1.1 8.6 16.7 1.5 8.2 16.7 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 CDC27 PF09507.10 CDJ48910.1 - 1.3 8.4 29.5 1.5 8.1 29.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HCO3_cotransp PF00955.21 CDJ48910.1 - 1.4 7.6 10.0 2.3 6.9 10.0 1.3 1 0 0 1 1 1 0 HCO3- transporter family Neur_chan_memb PF02932.16 CDJ48910.1 - 3 7.8 22.2 4.2 7.4 22.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paramyxo_ncap PF00973.19 CDJ48910.1 - 4.1 6.2 19.6 4.8 6.0 19.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Hid1 PF12722.7 CDJ48910.1 - 4.9 5.1 28.4 5.9 4.9 28.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 CDJ48910.1 - 5.1 6.8 30.2 7.8 6.2 30.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CDJ48910.1 - 5.9 3.9 27.5 6.6 3.7 27.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SKA1 PF07160.12 CDJ48910.1 - 6.4 6.5 29.3 8.8 6.1 29.3 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 VIR_N PF15912.5 CDJ48910.1 - 6.8 6.2 17.4 9.8 5.7 17.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF2151 PF10221.9 CDJ48910.1 - 7 5.1 18.6 8.9 4.8 18.6 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Presenilin PF01080.17 CDJ48912.1 - 0.4 9.4 31.3 0.42 9.3 31.3 1.1 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 CDJ48912.1 - 0.83 10.0 27.1 1 9.6 27.1 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Trypan_PARP PF05887.11 CDJ48912.1 - 1.6 8.7 6.8 1.9 8.5 6.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Zip PF02535.22 CDJ48912.1 - 2.8 7.1 17.0 2.9 7.0 17.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 CDJ48912.1 - 3.3 7.0 24.7 4.2 6.7 24.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Raftlin PF15250.6 CDJ48912.1 - 4.4 5.9 21.9 5.1 5.7 21.9 1.1 1 0 0 1 1 1 0 Raftlin CSG2 PF16965.5 CDJ48912.1 - 4.5 6.1 9.4 5 6.0 9.4 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Endostatin PF06482.11 CDJ48912.1 - 5.3 6.4 23.6 6.4 6.1 23.6 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin FAM60A PF15396.6 CDJ48912.1 - 6.1 6.8 22.7 6.9 6.6 22.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF4045 PF13254.6 CDJ48912.1 - 6.2 6.4 26.5 6.5 6.3 26.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF913 PF06025.12 CDJ48912.1 - 6.2 5.7 17.0 8.8 5.2 17.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CDJ48912.1 - 6.9 6.4 33.1 7.9 6.2 33.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ48912.1 - 9 4.5 25.9 10 4.2 25.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FancD2 PF14631.6 CDJ48912.1 - 9 3.5 15.6 10 3.4 15.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Ecl1 PF12855.7 CDJ48913.1 - 0.83 10.8 3.9 1.4 10.0 3.9 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins IHABP4_N PF16174.5 CDJ48914.1 - 0.67 10.5 38.0 0.88 10.2 38.0 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF5531 PF17671.1 CDJ48915.1 - 0.11 12.4 8.4 0.098 12.5 0.6 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5531) MIF PF01187.18 CDJ48916.1 - 2.8e-20 72.7 0.0 2.9e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) GHMP_kinases_N PF00288.26 CDJ48917.1 - 0.036 14.3 3.6 0.36 11.1 1.4 2.4 2 0 0 2 2 2 0 GHMP kinases N terminal domain DUF2681 PF10883.8 CDJ48917.1 - 0.058 13.8 1.9 0.058 13.8 1.9 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) LapA_dom PF06305.11 CDJ48917.1 - 0.14 12.0 0.2 0.14 12.0 0.2 3.6 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PAT1 PF09770.9 CDJ48917.1 - 2.2 6.5 51.1 3 6.0 51.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Myc_N PF01056.18 CDJ48917.1 - 3.7 7.3 26.7 4.8 7.0 26.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CDC27 PF09507.10 CDJ48917.1 - 4.6 6.5 37.3 5.5 6.3 37.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 LAP1C PF05609.12 CDJ48917.1 - 8.2 5.4 38.1 9.1 5.2 38.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PPP4R2 PF09184.11 CDJ48917.1 - 8.3 5.9 24.2 9.7 5.7 24.2 1.0 1 0 0 1 1 1 0 PPP4R2 SelP_N PF04592.14 CDJ48918.1 - 0.33 10.3 38.4 0.43 9.9 38.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CAF-1_p150 PF11600.8 CDJ48918.1 - 3.8 7.2 28.9 5 6.8 28.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SPX PF03105.19 CDJ48920.1 - 1.7e-05 24.9 10.7 1.7e-05 24.9 10.7 1.1 1 0 0 1 1 1 1 SPX domain Presenilin PF01080.17 CDJ48920.1 - 0.05 12.4 7.5 0.066 12.0 7.5 1.2 1 0 0 1 1 1 0 Presenilin FAM76 PF16046.5 CDJ48920.1 - 0.42 9.9 9.5 0.58 9.4 9.5 1.2 1 0 0 1 1 1 0 FAM76 protein Miga PF10265.9 CDJ48920.1 - 2.1 7.2 16.6 2.7 6.9 16.6 1.2 1 0 0 1 1 1 0 Mitoguardin Ctr PF04145.15 CDJ48920.1 - 2.3 8.8 5.9 4.9 7.8 5.9 1.6 1 1 0 1 1 1 0 Ctr copper transporter family Menin PF05053.13 CDJ48920.1 - 4.4 5.5 11.7 5.9 5.1 11.7 1.2 1 0 0 1 1 1 0 Menin PsbW PF07123.12 CDJ48921.1 - 0.025 14.6 0.1 0.025 14.6 0.1 3.9 2 1 2 4 4 2 0 Photosystem II reaction centre W protein (PsbW) Roughex PF06020.11 CDJ48921.1 - 0.25 10.4 33.9 0.34 9.9 23.6 2.3 2 0 0 2 2 2 0 Drosophila roughex protein SID-1_RNA_chan PF13965.6 CDJ48921.1 - 0.27 9.6 4.0 0.33 9.3 4.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MMR1 PF08505.10 CDJ48921.1 - 0.39 11.0 22.6 0.13 12.6 16.8 2.4 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein CDC45 PF02724.14 CDJ48921.1 - 0.45 8.7 17.1 0.87 7.8 17.1 1.5 1 0 0 1 1 1 0 CDC45-like protein TERB2 PF15101.6 CDJ48921.1 - 1 9.4 24.7 0.45 10.5 19.0 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4471 PF14740.6 CDJ48921.1 - 1.5 8.0 11.7 2.7 7.2 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF2151 PF10221.9 CDJ48921.1 - 2.9 6.4 12.7 5 5.6 12.7 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator Spt20 PF12090.8 CDJ48921.1 - 3.4 7.2 57.6 2.2 7.8 5.7 2.4 2 0 0 2 2 2 0 Spt20 family DUF5523 PF17661.1 CDJ48921.1 - 4 7.1 25.3 0.94 9.1 20.5 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5523) MCM_bind PF09739.9 CDJ48921.1 - 4.9 5.5 17.6 9 4.6 17.6 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SpoIIP PF07454.11 CDJ48921.1 - 5.5 6.4 24.0 0.44 10.0 18.4 1.8 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Cellulose_synt PF03552.14 CDJ48921.1 - 9.9 4.5 6.7 14 4.0 6.7 1.1 1 0 0 1 1 1 0 Cellulose synthase Pyr_redox_2 PF07992.14 CDJ48922.1 - 1.2e-37 129.8 0.0 2.1e-21 76.5 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ48922.1 - 2e-23 82.8 1.1 9.4e-15 54.8 0.2 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ48922.1 - 2e-09 37.9 1.3 2.4e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ48922.1 - 6.4e-06 25.8 0.0 9.3e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CDJ48922.1 - 0.00017 21.0 0.9 3.9 6.7 0.7 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ48922.1 - 0.00019 20.2 1.3 0.012 14.3 0.6 2.8 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 CDJ48922.1 - 0.0003 20.0 1.7 0.056 12.5 1.3 2.5 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 CDJ48922.1 - 0.0014 17.8 3.4 0.0014 17.8 3.4 1.7 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CDJ48922.1 - 0.0017 18.6 0.5 0.0042 17.3 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDJ48922.1 - 0.031 13.9 4.7 2.4 7.7 1.9 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 CDJ48922.1 - 0.037 13.2 0.1 0.088 12.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 CDJ48922.1 - 0.12 11.4 0.2 0.23 10.5 0.2 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein BOP1NT PF08145.12 CDJ48923.1 - 2.8e-27 96.3 3.8 2.8e-27 96.3 3.8 2.3 2 1 1 3 3 3 1 BOP1NT (NUC169) domain SR-25 PF10500.9 CDJ48923.1 - 0.00074 19.2 10.3 0.00074 19.2 10.3 3.7 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ48923.1 - 0.0035 17.4 5.0 0.0035 17.4 5.0 1.9 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) WD40 PF00400.32 CDJ48923.1 - 0.0036 18.1 0.0 28 5.8 0.0 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ48923.1 - 0.0057 16.9 0.0 11 6.4 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Apt1 PF10351.9 CDJ48923.1 - 0.014 14.3 24.2 0.073 11.9 12.6 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain INSIG PF07281.12 CDJ48923.1 - 0.068 12.8 0.3 0.16 11.6 0.3 1.6 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) Neuraminidase PF18413.1 CDJ48923.1 - 0.34 10.5 3.0 0.77 9.4 3.0 1.5 1 0 0 1 1 1 0 Neuraminidase-like domain Velvet PF11754.8 CDJ48923.1 - 6.4 6.6 26.9 1.4 8.8 5.2 2.3 2 1 0 2 2 2 0 Velvet factor Presenilin PF01080.17 CDJ48923.1 - 7.8 5.2 18.1 2.6 6.7 7.1 2.3 2 0 0 2 2 2 0 Presenilin Complex1_LYR PF05347.15 CDJ48924.1 - 6.5e-05 22.9 1.4 0.00016 21.7 1.4 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RskA PF10099.9 CDJ48924.1 - 0.00062 20.1 24.2 0.011 16.0 1.5 3.1 1 1 1 2 2 2 2 Anti-sigma-K factor rskA Complex1_LYR_2 PF13233.6 CDJ48924.1 - 0.0048 17.6 5.3 0.015 16.0 5.3 1.9 1 1 0 1 1 1 1 Complex1_LYR-like BAF1_ABF1 PF04684.13 CDJ48924.1 - 0.16 11.0 10.2 0.19 10.7 10.2 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4179 PF13786.6 CDJ48924.1 - 0.82 10.2 13.0 14 6.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DDOST_48kD PF03345.14 CDJ48924.1 - 9.7 4.9 8.0 12 4.6 8.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta RPOL_N PF14700.6 CDJ48925.1 - 1.2e-05 24.8 22.0 0.0059 16.0 0.2 2.2 2 0 0 2 2 2 2 DNA-directed RNA polymerase N-terminal FGF-BP1 PF06473.12 CDJ48925.1 - 0.00014 21.8 14.1 0.00014 21.8 14.1 2.4 2 0 0 2 2 2 1 FGF binding protein 1 (FGF-BP1) EPL1 PF10513.9 CDJ48925.1 - 0.005 17.2 20.0 0.4 11.1 1.0 2.7 2 0 0 2 2 2 2 Enhancer of polycomb-like TFIIA PF03153.13 CDJ48925.1 - 0.0053 16.8 77.2 0.025 14.6 48.4 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ48925.1 - 0.028 13.9 22.1 0.13 11.7 14.4 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Otopetrin PF03189.13 CDJ48925.1 - 0.043 12.6 3.3 2.2 7.0 4.1 2.1 2 0 0 2 2 2 0 Otopetrin CDC45 PF02724.14 CDJ48925.1 - 0.12 10.6 16.4 0.58 8.4 13.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF4471 PF14740.6 CDJ48925.1 - 0.13 11.4 9.2 4.5 6.4 7.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) FAM60A PF15396.6 CDJ48925.1 - 0.17 11.9 16.8 5.8 6.9 13.2 2.2 2 0 0 2 2 2 0 Protein Family FAM60A LTV PF04180.14 CDJ48925.1 - 0.2 11.4 17.5 2 8.1 11.2 2.1 2 0 0 2 2 2 0 Low temperature viability protein Sec62 PF03839.16 CDJ48925.1 - 0.22 11.0 17.5 1.9 7.9 0.1 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 CNDH2_C PF16858.5 CDJ48925.1 - 0.45 10.4 23.7 0.014 15.3 7.2 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Lin-8 PF03353.15 CDJ48925.1 - 0.45 10.0 34.2 0.34 10.4 17.6 2.5 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist GPCR_chapero_1 PF11904.8 CDJ48925.1 - 0.63 9.4 11.1 6.4 6.1 7.0 2.2 2 0 0 2 2 2 0 GPCR-chaperone Dynamin_N PF00350.23 CDJ48925.1 - 1.6 8.8 9.6 18 5.4 7.7 2.2 2 0 0 2 2 2 0 Dynamin family Mem_trans PF03547.18 CDJ48925.1 - 2 6.7 4.2 3.7 5.9 4.2 1.5 1 0 0 1 1 1 0 Membrane transport protein CAF1 PF04857.20 CDJ48925.1 - 2.3 7.3 13.8 10 5.2 0.0 2.2 2 0 0 2 2 2 0 CAF1 family ribonuclease SAPS PF04499.15 CDJ48925.1 - 3.1 6.5 18.6 0.028 13.2 7.0 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 CDJ48925.1 - 3.3 6.4 19.8 1 8.1 11.6 2.3 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 YTH PF04146.15 CDJ48925.1 - 3.5 7.5 11.5 32 4.4 8.7 2.2 2 0 0 2 2 2 0 YT521-B-like domain DUF2052 PF09747.9 CDJ48925.1 - 4.6 7.3 31.1 0.38 10.9 16.7 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ48925.1 - 9.3 6.0 35.8 0.11 12.3 19.2 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Serinc PF03348.15 CDJ48925.1 - 9.7 5.0 20.3 0.015 14.2 5.5 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) PLA2_inh PF02988.15 CDJ48928.1 - 0.11 13.1 3.5 0.28 11.8 3.5 1.6 1 0 0 1 1 1 0 Phospholipase A2 inhibitor Herpes_pp85 PF04637.12 CDJ48928.1 - 1.7 6.9 20.1 2.5 6.4 7.7 2.2 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF2852 PF11014.8 CDJ48928.1 - 1.9 8.7 10.5 0.092 12.9 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) RskA PF10099.9 CDJ48929.1 - 7.4e-07 29.6 13.0 0.00017 21.9 0.0 2.2 1 1 0 2 2 2 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ48929.1 - 1.6 8.3 15.6 2.4 7.7 15.6 1.2 1 0 0 1 1 1 0 Spt20 family GYF PF02213.16 CDJ48930.1 - 1.3e-10 40.8 4.8 3.1e-10 39.6 4.8 1.6 1 0 0 1 1 1 1 GYF domain PFK PF00365.20 CDJ48931.1 - 6.9e-53 179.8 0.0 5.8e-34 117.7 0.0 2.6 2 2 0 2 2 2 2 Phosphofructokinase TFIIA PF03153.13 CDJ48931.1 - 0.00054 20.1 18.3 0.00088 19.4 18.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ48931.1 - 0.0036 17.0 14.3 0.0078 15.8 14.3 1.5 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ48931.1 - 0.015 14.3 8.8 0.025 13.6 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Hydrolase_3 PF08282.12 CDJ48932.1 - 8.3e-42 143.7 0.0 1e-41 143.4 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ48932.1 - 1.8e-06 27.6 0.0 0.00011 21.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase SR-25 PF10500.9 CDJ48937.1 - 0.0039 16.8 8.6 0.0039 16.8 8.6 5.9 4 2 0 5 5 5 3 Nuclear RNA-splicing-associated protein SbcCD_C PF13558.6 CDJ48937.1 - 0.33 11.2 0.1 0.33 11.2 0.1 5.6 5 1 1 6 6 6 0 Putative exonuclease SbcCD, C subunit Macoilin PF09726.9 CDJ48938.1 - 7e-05 21.6 8.1 7.9e-05 21.4 8.1 1.1 1 0 0 1 1 1 1 Macoilin family SPX PF03105.19 CDJ48938.1 - 9.3e-05 22.5 8.9 9.3e-05 22.5 8.9 1.1 1 0 0 1 1 1 1 SPX domain Ndc1_Nup PF09531.10 CDJ48938.1 - 0.0009 18.1 6.8 0.00098 17.9 6.8 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 CDJ48938.1 - 0.0024 16.8 14.6 0.0028 16.6 14.6 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Mem_trans PF03547.18 CDJ48938.1 - 0.015 13.8 1.0 0.013 14.0 1.0 1.1 1 0 0 1 1 1 0 Membrane transport protein TFIIA PF03153.13 CDJ48938.1 - 0.056 13.4 18.8 0.066 13.2 18.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4692 PF15763.5 CDJ48938.1 - 0.078 13.5 19.7 0.06 13.8 17.9 1.7 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) PNISR PF15996.5 CDJ48938.1 - 0.095 13.0 17.1 0.13 12.6 17.1 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF4718 PF15842.5 CDJ48938.1 - 0.13 12.0 10.1 0.23 11.3 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) MAP65_ASE1 PF03999.12 CDJ48938.1 - 0.32 9.6 20.5 0.39 9.4 20.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SR-25 PF10500.9 CDJ48938.1 - 0.37 10.4 38.8 0.15 11.6 34.8 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 CDJ48938.1 - 1.1 8.8 18.7 1.4 8.4 18.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CDJ48938.1 - 1.1 8.8 24.8 1.8 8.1 24.8 1.3 1 0 0 1 1 1 0 Spt20 family Mucin PF01456.17 CDJ48938.1 - 3.3 7.7 12.4 6.6 6.7 12.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1635 PF07795.11 CDJ48938.1 - 3.9 7.3 17.6 6.8 6.5 17.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Peptidase_S64 PF08192.11 CDJ48938.1 - 4.1 5.8 21.0 5.2 5.4 21.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Herpes_capsid PF06112.11 CDJ48938.1 - 4.3 7.4 19.0 2.8 8.0 16.9 1.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein CDK2AP PF09806.9 CDJ48938.1 - 4.8 7.2 18.2 7.6 6.5 18.2 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein MPM1 PF17234.2 CDJ48938.1 - 6.2 7.0 17.5 10 6.3 17.5 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 PI3K_1B_p101 PF10486.9 CDJ48938.1 - 6.4 4.4 15.2 8.8 4.0 15.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Roughex PF06020.11 CDJ48938.1 - 7.8 5.5 10.2 12 4.9 10.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 CDJ48938.1 - 9.3 4.9 21.5 11 4.6 21.5 1.1 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.12 CDJ48939.1 - 4 6.0 42.0 5.4 5.6 42.0 1.1 1 0 0 1 1 1 0 Hamartin protein Apc15p PF05841.11 CDJ48940.1 - 1.8 9.3 7.6 0.12 13.2 2.5 1.8 2 0 0 2 2 2 0 Apc15p protein Mcm10 PF09332.11 CDJ48940.1 - 8.9 5.6 8.3 11 5.3 8.1 1.4 1 1 0 1 1 1 0 Mcm10 replication factor PCRF PF03462.18 CDJ48941.1 - 0.081 12.8 4.6 0.091 12.6 4.6 1.1 1 0 0 1 1 1 0 PCRF domain Zw10 PF06248.13 CDJ48941.1 - 0.59 8.6 2.4 0.71 8.4 2.4 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 T2SSF PF00482.23 CDJ48941.1 - 1.4 8.9 4.6 13 5.8 4.6 2.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DivIVA PF05103.13 CDJ48941.1 - 2.2 8.4 8.4 4.4 7.4 6.3 2.0 1 1 1 2 2 2 0 DivIVA protein LUC7 PF03194.15 CDJ48941.1 - 2.7 7.6 8.1 2.9 7.5 8.1 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Halo_GVPC PF05465.13 CDJ48941.1 - 5.1 7.5 6.1 22 5.4 0.5 2.9 1 1 2 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat Hamartin PF04388.12 CDJ48942.1 - 0.068 11.8 25.5 0.089 11.4 25.5 1.1 1 0 0 1 1 1 0 Hamartin protein DUF2722 PF10846.8 CDJ48943.1 - 0.00048 19.2 9.0 0.00048 19.2 9.0 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ48943.1 - 0.00067 19.3 15.4 0.00067 19.3 15.4 3.0 2 1 0 2 2 2 1 Spt20 family RNase_H PF00075.24 CDJ48943.1 - 0.0047 17.1 0.3 0.0047 17.1 0.3 3.2 2 1 1 3 3 3 2 RNase H Band_3_cyto PF07565.13 CDJ48943.1 - 0.17 11.6 12.8 0.54 10.0 1.4 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.12 CDJ48943.1 - 7.2 5.5 25.4 4.8 6.0 6.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.6 CDJ48943.1 - 9.3 6.2 13.5 8.8 6.3 3.6 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Apt1 PF10351.9 CDJ48944.1 - 0.3 9.9 8.5 0.33 9.7 8.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIA PF03153.13 CDJ48944.1 - 0.69 9.9 5.2 0.85 9.5 5.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Collagen PF01391.18 CDJ48945.1 - 0.0015 18.2 13.8 0.0056 16.4 13.8 1.8 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) SARAF PF06682.12 CDJ48947.1 - 0.00052 19.8 11.8 0.00052 19.8 11.8 8.0 5 2 1 7 7 7 1 SOCE-associated regulatory factor of calcium homoeostasis TAF4 PF05236.14 CDJ48947.1 - 0.0077 16.0 10.2 0.0077 16.0 10.2 8.6 6 3 1 7 7 7 1 Transcription initiation factor TFIID component TAF4 family CNDH2_C PF16858.5 CDJ48947.1 - 0.019 14.9 0.5 0.019 14.9 0.5 5.9 5 2 0 5 5 5 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Rpn3_C PF08375.11 CDJ48948.1 - 4.1e-20 72.0 2.5 4.1e-20 72.0 2.5 4.1 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal SR-25 PF10500.9 CDJ48948.1 - 5.4e-08 32.7 40.4 2.5e-05 24.0 13.5 3.9 4 0 0 4 4 4 3 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ48948.1 - 4.3e-05 23.6 2.5 4.3e-05 23.6 2.5 3.5 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) Secretin_N_2 PF07655.13 CDJ48948.1 - 0.00023 21.6 8.3 0.00023 21.6 8.3 4.6 3 1 0 3 3 3 1 Secretin N-terminal domain MID_MedPIWI PF18296.1 CDJ48948.1 - 0.017 14.9 35.7 0.61 9.8 2.9 3.6 3 0 0 3 3 3 0 MID domain of medPIWI RskA PF10099.9 CDJ48948.1 - 0.12 12.6 43.0 0.54 10.5 4.5 4.5 4 0 0 4 4 4 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ48948.1 - 0.33 9.7 41.9 0.26 10.0 18.6 3.5 3 0 0 3 3 3 0 Presenilin Velvet PF11754.8 CDJ48948.1 - 2.9 7.8 51.5 0.5 10.3 23.6 3.4 2 1 1 3 3 3 0 Velvet factor V_ATPase_I PF01496.19 CDJ48948.1 - 3.6 5.4 34.9 0.051 11.5 8.2 3.1 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family MMR1 PF08505.10 CDJ48948.1 - 4.8 7.4 52.0 0.096 13.0 18.1 3.6 3 1 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein Tropomyosin PF00261.20 CDJ48949.1 - 0.0067 15.8 16.3 0.0067 15.8 16.3 4.8 1 1 2 4 4 4 1 Tropomyosin DUF2031 PF09592.10 CDJ48949.1 - 0.034 13.7 0.5 4.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) IL6 PF00489.17 CDJ48949.1 - 0.11 12.0 2.7 0.36 10.4 2.7 1.9 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family LCE PF14672.6 CDJ48949.1 - 1.7 9.3 12.2 5.1 7.8 12.2 1.8 1 0 0 1 1 1 0 Late cornified envelope Jacalin PF01419.17 CDJ48951.1 - 5.3 7.0 6.9 2 8.3 1.4 3.2 2 0 0 2 2 2 0 Jacalin-like lectin domain Pex14_N PF04695.13 CDJ48954.1 - 4.5 7.9 61.0 0.28 11.8 1.3 3.9 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RIFIN PF02009.16 CDJ48954.1 - 8 6.2 29.6 0.61 9.9 12.7 2.4 2 0 0 2 2 2 0 Rifin PA26 PF04636.13 CDJ48954.1 - 8.4 5.2 30.9 0.61 8.9 9.2 2.4 2 1 0 2 2 2 0 PA26 p53-induced protein (sestrin) DUF4667 PF15700.5 CDJ48955.1 - 0.0008 19.6 11.5 0.21 11.6 6.9 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ48955.1 - 0.009 15.7 43.0 0.031 13.9 20.1 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ48955.1 - 0.015 14.9 10.3 0.029 14.0 10.3 1.3 1 0 0 1 1 1 0 Spt20 family Apt1 PF10351.9 CDJ48955.1 - 0.017 14.0 5.4 0.25 10.2 3.0 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF508 PF04370.12 CDJ48955.1 - 0.022 14.5 2.5 0.022 14.5 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF508) TAF4 PF05236.14 CDJ48955.1 - 0.048 13.4 18.4 0.024 14.4 8.0 3.1 2 1 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family DUF1645 PF07816.11 CDJ48955.1 - 0.24 12.0 19.1 0.75 10.3 8.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF4614 PF15391.6 CDJ48955.1 - 1 9.3 16.5 1.1 9.2 5.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) DDHD PF02862.17 CDJ48955.1 - 1.2 9.2 5.5 3.5 7.7 4.3 2.0 2 0 0 2 2 2 0 DDHD domain SPX PF03105.19 CDJ48955.1 - 2.4 8.0 16.6 5.1 6.9 0.9 2.1 2 0 0 2 2 2 0 SPX domain Lin-8 PF03353.15 CDJ48955.1 - 5 6.6 9.7 3.5 7.1 5.3 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist RskA PF10099.9 CDJ48956.1 - 0.017 15.4 7.7 0.017 15.4 7.7 3.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA PPP4R2 PF09184.11 CDJ48956.1 - 1.1 8.8 11.4 1.3 8.5 11.4 1.0 1 0 0 1 1 1 0 PPP4R2 Connexin PF00029.19 CDJ48956.1 - 2.3 7.9 5.7 2.7 7.7 5.7 1.3 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ48956.1 - 2.4 6.8 17.8 3.4 6.3 17.8 1.3 1 0 0 1 1 1 0 Presenilin Roughex PF06020.11 CDJ48956.1 - 2.4 7.2 9.1 2.7 7.0 9.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SLC12 PF03522.15 CDJ48956.1 - 2.4 7.1 10.2 2.8 6.9 10.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ48956.1 - 2.6 7.8 12.4 3 7.6 12.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 CDJ48956.1 - 4.6 7.3 24.2 6.6 6.8 24.2 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated GREB1 PF15782.5 CDJ48956.1 - 7.7 3.5 17.4 7.8 3.5 17.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 CDJ48956.1 - 8.6 4.7 15.6 11 4.4 15.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.9 CDJ48957.1 - 0.00041 19.1 18.0 0.00062 18.5 18.0 1.2 1 0 0 1 1 1 1 Macoilin family NARP1 PF12569.8 CDJ48957.1 - 0.0085 15.0 14.4 0.013 14.5 14.4 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 CDC45 PF02724.14 CDJ48957.1 - 0.0085 14.4 9.5 0.012 13.9 9.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Sec62 PF03839.16 CDJ48957.1 - 0.013 15.0 8.0 0.022 14.3 8.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Striatin PF08232.12 CDJ48957.1 - 0.028 15.0 23.2 0.041 14.5 20.5 2.1 2 0 0 2 2 2 0 Striatin family Serinc PF03348.15 CDJ48957.1 - 0.03 13.3 4.6 0.049 12.6 4.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) PH_4 PF15404.6 CDJ48957.1 - 0.059 13.2 5.7 0.16 11.8 5.7 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain DUF4746 PF15928.5 CDJ48957.1 - 0.11 11.9 10.6 0.16 11.4 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MDM31_MDM32 PF08118.11 CDJ48957.1 - 0.16 10.6 8.7 0.28 9.8 8.7 1.3 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins UPF0172 PF03665.13 CDJ48957.1 - 0.17 11.9 7.5 0.28 11.2 7.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) SID-1_RNA_chan PF13965.6 CDJ48957.1 - 0.2 10.1 1.4 0.22 9.9 1.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 UPF0565 PF10561.9 CDJ48957.1 - 0.23 10.7 6.4 0.32 10.2 6.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Band_3_cyto PF07565.13 CDJ48957.1 - 0.36 10.6 17.6 0.12 12.2 14.1 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain SART-1 PF03343.13 CDJ48957.1 - 0.48 8.9 21.9 0.67 8.4 21.9 1.1 1 0 0 1 1 1 0 SART-1 family XRN_M PF17846.1 CDJ48957.1 - 0.88 8.5 9.8 1.1 8.1 9.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Ureide_permease PF07168.11 CDJ48957.1 - 1.2 7.8 3.5 1.6 7.4 3.5 1.3 1 0 0 1 1 1 0 Ureide permease DUF3292 PF11696.8 CDJ48957.1 - 1.2 7.4 13.5 1.7 6.9 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Tim54 PF11711.8 CDJ48957.1 - 1.6 7.4 13.3 3.4 6.4 12.8 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 V_ATPase_I PF01496.19 CDJ48957.1 - 1.7 6.5 15.9 2.1 6.2 15.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paf1 PF03985.13 CDJ48957.1 - 1.7 7.5 20.7 3.8 6.4 20.7 1.5 1 0 0 1 1 1 0 Paf1 CLN3 PF02487.17 CDJ48957.1 - 1.8 7.5 8.3 2.8 6.9 8.3 1.4 1 0 0 1 1 1 0 CLN3 protein ZYG-11_interact PF05884.12 CDJ48957.1 - 2.3 7.5 11.5 3.5 7.0 11.5 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 SLC12 PF03522.15 CDJ48957.1 - 2.5 7.0 16.6 4.1 6.3 16.6 1.4 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 CDJ48957.1 - 2.6 6.8 14.1 4.5 6.0 14.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter F-protein PF00469.20 CDJ48957.1 - 2.7 7.5 15.6 5.2 6.6 15.6 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Presenilin PF01080.17 CDJ48957.1 - 3.1 6.5 23.8 0.49 9.1 17.3 2.1 2 0 0 2 2 2 0 Presenilin DUF913 PF06025.12 CDJ48957.1 - 5 6.0 13.1 0.36 9.8 6.5 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Exonuc_VII_L PF02601.15 CDJ48957.1 - 6.3 6.3 26.2 9.6 5.7 26.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CSG2 PF16965.5 CDJ48957.1 - 8.6 5.2 6.0 15 4.4 6.0 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator DUF382 PF04037.13 CDJ48958.1 - 0.17 12.1 3.4 0.34 11.1 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF382) DUF572 PF04502.13 CDJ48958.1 - 2.3 7.8 18.5 3.1 7.3 18.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) MRP-S26 PF14943.6 CDJ48958.1 - 3 7.7 14.2 0.52 10.2 8.3 2.1 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 CemA PF03040.14 CDJ48958.1 - 7.5 6.4 7.5 3.5 7.5 3.7 1.9 2 0 0 2 2 2 0 CemA family Kinesin_assoc PF16183.5 CDJ48958.1 - 8.4 6.5 12.4 0.72 10.0 6.1 2.2 1 1 1 2 2 2 0 Kinesin-associated Cytochrom_C_asm PF01578.20 CDJ48959.1 - 0.18 11.6 0.1 0.18 11.6 0.1 1.7 2 0 0 2 2 2 0 Cytochrome C assembly protein Ribosomal_60s PF00428.19 CDJ48959.1 - 0.3 11.7 19.6 0.29 11.8 14.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ferlin_C PF16165.5 CDJ48959.1 - 0.56 10.1 8.5 0.97 9.4 5.4 2.0 2 0 0 2 2 2 0 Ferlin C-terminus RskA PF10099.9 CDJ48959.1 - 4 7.7 41.4 0.014 15.7 21.5 2.9 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Peptidase_S49_N PF08496.10 CDJ48959.1 - 5.7 7.0 23.0 0.5 10.4 5.2 3.1 3 0 0 3 3 3 0 Peptidase family S49 N-terminal zf-RVT PF13966.6 CDJ48961.1 - 8.2e-07 29.7 2.1 9.2e-07 29.5 0.6 1.8 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase 2-Hacid_dh_C PF02826.19 CDJ48961.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SUIM_assoc PF16619.5 CDJ48963.1 - 0.046 13.8 3.9 0.074 13.1 3.9 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Asp-Al_Ex PF06826.12 CDJ48963.1 - 0.84 9.4 5.4 0.99 9.2 5.4 1.1 1 0 0 1 1 1 0 Predicted Permease Membrane Region SR-25 PF10500.9 CDJ48964.1 - 0.00048 19.8 37.4 0.0047 16.6 33.5 2.7 2 1 0 2 2 2 2 Nuclear RNA-splicing-associated protein Serinc PF03348.15 CDJ48964.1 - 1.6 7.6 14.4 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) Endostatin PF06482.11 CDJ48964.1 - 7.5 5.9 33.9 4.1 6.8 6.3 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Spore_YhcN_YlaJ PF09580.10 CDJ48966.1 - 0.072 13.2 0.0 0.072 13.2 0.0 12.0 10 4 0 10 10 10 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF3883 PF13020.6 CDJ48966.1 - 0.13 12.3 0.0 2.6 8.1 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3883) NPAT_C PF15712.5 CDJ48967.1 - 0.00011 21.0 13.0 0.00013 20.8 13.0 1.2 1 0 0 1 1 1 1 NPAT C terminus Vfa1 PF08432.10 CDJ48967.1 - 0.078 13.3 18.7 0.09 13.1 18.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF5523 PF17661.1 CDJ48967.1 - 0.078 12.7 13.4 0.095 12.4 13.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF5427 PF10310.9 CDJ48967.1 - 0.092 11.7 19.7 0.098 11.6 19.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Hydin_ADK PF17213.3 CDJ48967.1 - 0.099 12.9 12.9 0.11 12.7 12.9 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Pex14_N PF04695.13 CDJ48967.1 - 0.1 13.2 15.2 0.14 12.8 15.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Roughex PF06020.11 CDJ48967.1 - 0.11 11.6 13.1 0.13 11.3 13.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein NPR3 PF03666.13 CDJ48967.1 - 0.12 11.1 12.8 0.13 11.1 12.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Menin PF05053.13 CDJ48967.1 - 0.13 10.6 11.2 0.14 10.5 11.2 1.0 1 0 0 1 1 1 0 Menin MAJIN PF15077.6 CDJ48967.1 - 0.16 11.7 9.6 0.16 11.7 9.6 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Suf PF05843.14 CDJ48967.1 - 0.18 11.8 14.2 0.19 11.7 14.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4050 PF13259.6 CDJ48967.1 - 0.19 12.0 9.5 0.24 11.7 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) eIF3_subunit PF08597.10 CDJ48967.1 - 0.25 11.2 22.1 0.31 10.9 22.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit BAF1_ABF1 PF04684.13 CDJ48967.1 - 0.38 9.7 16.8 0.46 9.5 16.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDC27 PF09507.10 CDJ48967.1 - 0.39 10.0 22.2 0.41 10.0 22.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Raftlin PF15250.6 CDJ48967.1 - 0.49 9.1 11.5 0.5 9.0 11.5 1.0 1 0 0 1 1 1 0 Raftlin SMYLE_N PF18615.1 CDJ48967.1 - 0.7 9.4 10.5 0.78 9.2 10.5 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF3474 PF11960.8 CDJ48967.1 - 0.92 9.7 5.1 1.2 9.3 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Dicty_REP PF05086.12 CDJ48967.1 - 0.94 7.4 10.9 0.97 7.3 10.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sin_N PF04801.13 CDJ48967.1 - 0.98 8.6 18.9 1.4 8.1 18.9 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region SAPS PF04499.15 CDJ48967.1 - 1 8.1 12.9 1.1 8.0 12.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 CDJ48967.1 - 1.1 8.2 15.3 1.2 8.1 15.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4746 PF15928.5 CDJ48967.1 - 1.2 8.5 10.7 1.5 8.2 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DDHD PF02862.17 CDJ48967.1 - 1.3 9.2 11.8 1.6 8.9 11.8 1.3 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ48967.1 - 1.3 7.9 15.4 1.4 7.8 15.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 CDJ48967.1 - 1.4 8.7 19.8 1.7 8.4 19.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ48967.1 - 1.4 7.1 14.9 1.7 6.9 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 CDJ48967.1 - 1.5 8.0 13.7 1.6 7.8 13.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 CDJ48967.1 - 1.6 8.7 15.6 1.7 8.6 15.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Rtf2 PF04641.12 CDJ48967.1 - 1.6 8.0 20.9 2 7.7 20.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Asp-B-Hydro_N PF05279.11 CDJ48967.1 - 1.8 8.5 15.5 2.3 8.2 15.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 CDJ48967.1 - 1.9 7.2 19.8 1.9 7.2 19.8 1.0 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 CDJ48967.1 - 2 8.5 14.2 2.3 8.3 14.2 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region TFIIA PF03153.13 CDJ48967.1 - 2.3 8.1 25.7 2.4 8.0 25.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF913 PF06025.12 CDJ48967.1 - 2.3 7.1 10.6 2.6 6.9 10.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PA26 PF04636.13 CDJ48967.1 - 2.6 6.9 11.1 2.7 6.8 11.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MCM_bind PF09739.9 CDJ48967.1 - 2.7 6.3 16.1 2.9 6.3 16.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Membralin PF09746.9 CDJ48967.1 - 2.8 6.9 7.3 2.9 6.8 7.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein GREB1 PF15782.5 CDJ48967.1 - 2.8 5.0 13.1 2.8 5.0 13.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF572 PF04502.13 CDJ48967.1 - 2.9 7.4 18.5 3.4 7.2 18.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Band_3_cyto PF07565.13 CDJ48967.1 - 3.2 7.5 10.5 3.8 7.2 10.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3450 PF11932.8 CDJ48967.1 - 3.2 7.0 20.0 3.6 6.8 20.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spore_coat_CotO PF14153.6 CDJ48967.1 - 3.6 7.5 21.8 4.8 7.1 21.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO ALMT PF11744.8 CDJ48967.1 - 3.9 6.2 11.0 4.2 6.1 11.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 CDJ48967.1 - 4.4 7.3 11.6 5.1 7.1 11.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4569 PF15133.6 CDJ48967.1 - 4.5 6.9 16.7 5.2 6.7 16.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Gti1_Pac2 PF09729.9 CDJ48967.1 - 5.3 7.1 12.9 7.5 6.6 12.9 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Sec62 PF03839.16 CDJ48967.1 - 5.7 6.4 14.4 7.1 6.1 14.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 SelP_N PF04592.14 CDJ48967.1 - 6.3 6.1 19.3 8.8 5.7 19.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CLN3 PF02487.17 CDJ48967.1 - 6.6 5.7 8.2 7.7 5.4 8.2 1.3 1 0 0 1 1 1 0 CLN3 protein Otopetrin PF03189.13 CDJ48967.1 - 7.2 5.3 6.7 7.4 5.3 6.7 1.1 1 0 0 1 1 1 0 Otopetrin CSG2 PF16965.5 CDJ48967.1 - 7.9 5.3 6.8 8.4 5.2 6.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Cellulose_synt PF03552.14 CDJ48967.1 - 8.9 4.7 5.6 8.5 4.7 5.6 1.0 1 0 0 1 1 1 0 Cellulose synthase Helicase_C PF00271.31 CDJ48968.1 - 1.3e-26 93.1 0.0 4.1e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 CDJ48968.1 - 2.9e-06 27.5 0.0 0.0033 17.7 0.0 2.6 1 1 1 2 2 2 2 GUCT (NUC152) domain DUF3157 PF11355.8 CDJ48968.1 - 0.00098 18.8 0.3 0.00098 18.8 0.3 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3157) AF-4 PF05110.13 CDJ48968.1 - 0.067 11.3 20.9 0.085 10.9 20.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein eIF-3_zeta PF05091.12 CDJ48968.1 - 5.4 5.9 13.2 7.3 5.4 13.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AbrB_C PF18277.1 CDJ48969.1 - 0.039 13.6 0.1 0.11 12.1 0.1 1.8 1 0 0 1 1 1 0 AbrB C-terminal domain CRM1_C PF08767.11 CDJ48970.1 - 2.8e-106 355.3 0.3 1.7e-105 352.7 0.0 1.9 2 0 0 2 2 2 1 CRM1 C terminal Vac14_Fab1_bd PF12755.7 CDJ48970.1 - 0.0053 17.3 0.5 5.8 7.6 0.0 3.1 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region DUF2497 PF10691.9 CDJ48970.1 - 0.031 14.7 0.1 0.089 13.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) IFRD PF05004.13 CDJ48970.1 - 0.083 12.0 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) BID PF06393.11 CDJ48970.1 - 0.1 12.1 0.1 0.45 10.0 0.0 2.1 2 0 0 2 2 2 0 BH3 interacting domain (BID) PI3K_p85B PF02192.16 CDJ48970.1 - 0.11 12.3 0.2 12 5.7 0.0 2.5 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain Ribosomal_60s PF00428.19 CDJ48970.1 - 0.27 11.8 15.4 0.24 12.0 9.2 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Shadoo PF14999.6 CDJ48971.1 - 0.76 9.9 10.7 2 8.5 10.7 1.7 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective SOG2 PF10428.9 CDJ48972.1 - 0.066 12.4 7.6 0.069 12.3 7.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Bul1_N PF04425.12 CDJ48972.1 - 0.22 10.3 0.9 0.25 10.0 0.9 1.1 1 0 0 1 1 1 0 Bul1 N terminus SR-25 PF10500.9 CDJ48972.1 - 0.24 11.0 18.4 0.37 10.4 18.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.13 CDJ48972.1 - 3.4 6.6 5.6 4.8 6.1 5.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor AF-4 PF05110.13 CDJ48972.1 - 4.3 5.3 15.1 5.1 5.1 15.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Corona_nucleoca PF00937.18 CDJ48972.1 - 6.3 5.7 8.7 8.2 5.4 8.7 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein JUPITER PF17054.5 CDJ48972.1 - 6.9 6.0 12.7 9.8 5.5 12.7 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter RskA PF10099.9 CDJ48973.1 - 0.0031 17.9 9.4 0.0031 17.9 9.4 11.3 4 4 5 9 9 9 4 Anti-sigma-K factor rskA Syntaxin PF00804.25 CDJ48974.1 - 0.012 15.3 2.3 0.022 14.5 2.3 1.4 1 0 0 1 1 1 0 Syntaxin baeRF_family2 PF18844.1 CDJ48974.1 - 0.013 15.5 0.4 0.022 14.8 0.4 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 Rad10 PF03834.14 CDJ48974.1 - 0.047 13.7 0.1 0.086 12.9 0.1 1.4 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Phage_antitermQ PF06530.12 CDJ48974.1 - 0.048 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q Nod1 PF17114.5 CDJ48974.1 - 0.089 13.0 0.2 0.12 12.6 0.2 1.1 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 DASH_Dam1 PF08653.10 CDJ48974.1 - 0.13 12.1 0.3 0.33 10.8 0.1 1.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 Ctr PF04145.15 CDJ48975.1 - 0.005 17.5 5.1 0.005 17.5 5.1 2.3 1 1 1 2 2 2 1 Ctr copper transporter family DUF4045 PF13254.6 CDJ48975.1 - 0.56 9.8 37.8 0.75 9.4 37.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Dapper PF15268.6 CDJ48975.1 - 8.3 5.1 52.3 9.6 4.9 52.3 1.0 1 0 0 1 1 1 0 Dapper TFIIF_alpha PF05793.12 CDJ48976.1 - 1.7 7.1 24.5 0.0053 15.4 14.6 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Myosin_head PF00063.21 CDJ48978.1 - 3.1e-119 399.1 1.8 9.9e-90 301.6 0.0 3.3 3 0 0 3 3 3 3 Myosin head (motor domain) AAA_22 PF13401.6 CDJ48978.1 - 0.034 14.4 0.4 0.34 11.2 0.1 2.9 2 0 0 2 2 2 0 AAA domain Myosin_head PF00063.21 CDJ48979.1 - 1.1e-124 417.2 0.0 2e-88 297.3 0.0 3.2 3 0 0 3 3 3 3 Myosin head (motor domain) AAA_22 PF13401.6 CDJ48979.1 - 0.062 13.6 0.3 0.39 11.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CDJ48979.1 - 0.1 11.8 0.0 0.44 9.8 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 CDJ48979.1 - 0.17 12.3 1.3 1.7 9.0 0.4 3.2 2 1 1 3 3 3 0 AAA ATPase domain Presenilin PF01080.17 CDJ48982.1 - 0.42 9.3 39.6 0.46 9.2 39.6 1.0 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 CDJ48982.1 - 0.74 8.5 26.4 0.82 8.4 26.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM60A PF15396.6 CDJ48982.1 - 1.1 9.2 28.5 1.4 8.9 28.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2126 PF09899.9 CDJ48982.1 - 1.6 6.7 19.7 2.3 6.2 19.7 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2052 PF09747.9 CDJ48982.1 - 1.6 8.8 32.5 2 8.5 32.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) ALMT PF11744.8 CDJ48982.1 - 3.5 6.4 27.6 3.9 6.2 27.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 CDJ48982.1 - 4.8 6.9 36.3 6 6.6 36.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.9 CDJ48982.1 - 7 6.7 29.6 10 6.2 29.6 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Endostatin PF06482.11 CDJ48982.1 - 7.4 5.9 33.1 9.6 5.6 33.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SLC12 PF03522.15 CDJ48982.1 - 7.9 5.4 37.6 8.7 5.2 37.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF2722 PF10846.8 CDJ48983.1 - 5.1e-06 25.7 9.9 5.1e-06 25.7 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ48983.1 - 0.00044 20.4 18.4 0.00044 20.4 18.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Rtt102p PF09510.10 CDJ48983.1 - 0.0038 17.4 2.7 0.005 17.1 2.7 1.3 1 0 0 1 1 1 1 Rtt102p-like transcription regulator protein Sporozoite_P67 PF05642.11 CDJ48983.1 - 0.011 13.9 2.4 0.015 13.5 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4207 PF13904.6 CDJ48983.1 - 0.016 14.9 15.4 0.019 14.7 15.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Spt20 PF12090.8 CDJ48983.1 - 0.028 14.0 27.6 0.037 13.6 27.6 1.2 1 0 0 1 1 1 0 Spt20 family UPF0524 PF15823.5 CDJ48983.1 - 0.14 11.5 2.8 0.16 11.4 2.8 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 Ndc1_Nup PF09531.10 CDJ48983.1 - 0.22 10.2 9.4 0.22 10.1 9.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MMR1 PF08505.10 CDJ48983.1 - 0.26 11.6 9.5 0.3 11.4 9.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Roughex PF06020.11 CDJ48983.1 - 0.39 9.8 10.9 0.47 9.5 10.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Porph_ging PF09697.10 CDJ48983.1 - 0.4 11.3 4.4 0.85 10.2 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) Senescence_reg PF04520.13 CDJ48983.1 - 0.4 11.5 8.7 0.52 11.1 8.7 1.1 1 0 0 1 1 1 0 Senescence regulator BAF1_ABF1 PF04684.13 CDJ48983.1 - 0.51 9.3 10.3 0.6 9.1 10.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Gti1_Pac2 PF09729.9 CDJ48983.1 - 0.66 10.1 6.5 0.83 9.7 6.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4366 PF14283.6 CDJ48983.1 - 0.96 9.5 5.9 1.4 9.0 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) XRN_M PF17846.1 CDJ48983.1 - 0.98 8.3 8.2 1.1 8.2 8.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain SLC12 PF03522.15 CDJ48983.1 - 1.2 8.1 7.4 1.2 8.1 7.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Band_3_cyto PF07565.13 CDJ48983.1 - 1.2 8.9 6.2 1.4 8.7 6.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Folate_carrier PF01770.18 CDJ48983.1 - 1.2 7.7 3.8 1.8 7.2 3.8 1.4 1 0 0 1 1 1 0 Reduced folate carrier GREB1 PF15782.5 CDJ48983.1 - 2.4 5.2 10.1 2.3 5.2 10.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TERB2 PF15101.6 CDJ48983.1 - 3.1 7.8 13.4 4.3 7.3 13.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 UPF0560 PF10577.9 CDJ48983.1 - 3.6 6.0 15.0 4.3 5.7 15.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CLN3 PF02487.17 CDJ48983.1 - 3.8 6.4 5.3 4.4 6.3 5.3 1.1 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 CDJ48983.1 - 7.9 6.5 6.9 9.2 6.2 6.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ48983.1 - 8.8 5.0 7.2 10 4.8 7.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter eIF-3_zeta PF05091.12 CDJ48983.1 - 8.8 5.2 13.8 11 4.8 13.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Biotin_lipoyl PF00364.22 CDJ48984.1 - 2.5e-13 49.6 0.0 4.2e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RskA PF10099.9 CDJ48984.1 - 0.016 15.5 19.4 0.016 15.5 19.4 4.2 1 1 2 3 3 3 0 Anti-sigma-K factor rskA SWIRM-assoc_2 PF16496.5 CDJ48984.1 - 5 5.9 17.0 7.5 5.3 17.0 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal ASC PF00858.24 CDJ48987.1 - 1.1 8.2 15.1 19 4.0 0.0 2.9 1 1 1 2 2 2 0 Amiloride-sensitive sodium channel RAP1 PF07218.11 CDJ48988.1 - 0.041 12.2 14.1 0.053 11.8 14.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LAP1C PF05609.12 CDJ48988.1 - 2 7.4 48.6 2.1 7.3 48.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GAGA_bind PF06217.12 CDJ48988.1 - 7.5 6.8 35.4 9.7 6.4 35.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family AP2 PF00847.20 CDJ48989.1 - 4.2e-05 23.7 0.0 4.2e-05 23.7 0.0 4.8 5 0 0 5 5 5 1 AP2 domain TCP PF03634.13 CDJ48991.1 - 0.0036 17.9 3.4 0.0036 17.9 3.4 4.1 3 1 0 3 3 3 1 TCP family transcription factor ABC2_membrane_2 PF12679.7 CDJ48991.1 - 9.4 5.4 10.7 4.9 6.4 0.0 3.2 3 1 0 3 3 3 0 ABC-2 family transporter protein Filament_head PF04732.14 CDJ48991.1 - 9.7 7.1 29.0 2.6 9.0 6.3 4.0 4 0 0 4 4 4 0 Intermediate filament head (DNA binding) region TGT PF01702.18 CDJ48992.1 - 6.1e-08 32.2 0.0 1.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Ribosomal_L7Ae PF01248.26 CDJ48993.1 - 5.7e-26 90.1 0.3 7.5e-26 89.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CDJ48993.1 - 0.0087 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain DAP10 PF07213.11 CDJ48994.1 - 0.092 12.7 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 DAP10 membrane protein MSP1a PF11670.8 CDJ48994.1 - 0.25 10.6 7.9 6.8 5.9 4.1 2.4 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) GHMP_kinases_N PF00288.26 CDJ48995.1 - 0.0027 17.9 1.1 0.0027 17.9 1.1 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain MMR1 PF08505.10 CDJ48995.1 - 0.051 13.9 23.5 0.053 13.8 23.5 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SLC12 PF03522.15 CDJ48995.1 - 0.072 12.1 22.4 0.08 11.9 22.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 CDJ48995.1 - 0.1 11.4 22.8 0.11 11.2 22.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Smg8_Smg9 PF10220.9 CDJ48995.1 - 0.13 10.5 24.4 0.16 10.2 24.4 1.1 1 0 0 1 1 1 0 Smg8_Smg9 GAGA_bind PF06217.12 CDJ48995.1 - 0.16 12.2 18.0 0.18 12.0 18.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Zip PF02535.22 CDJ48995.1 - 0.2 10.8 12.8 0.24 10.6 12.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CDJ48995.1 - 0.21 11.6 20.1 0.26 11.3 20.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ48995.1 - 0.31 11.0 57.4 0.39 10.7 57.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAJIN PF15077.6 CDJ48995.1 - 0.34 10.6 18.9 0.39 10.5 18.9 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein CDC45 PF02724.14 CDJ48995.1 - 0.42 8.8 27.1 0.51 8.6 27.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4551 PF15087.6 CDJ48995.1 - 0.54 9.0 15.8 0.56 9.0 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4778 PF16008.5 CDJ48995.1 - 0.59 10.1 21.1 0.65 10.0 21.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) SR-25 PF10500.9 CDJ48995.1 - 0.6 9.7 36.0 1.1 8.8 35.3 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Shadoo PF14999.6 CDJ48995.1 - 0.61 10.2 20.4 1.4 9.0 3.0 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective SOBP PF15279.6 CDJ48995.1 - 0.89 10.1 19.6 0.99 10.0 19.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Auxin_canalis PF05703.11 CDJ48995.1 - 1.2 9.0 45.8 0.081 12.8 25.9 2.0 1 1 1 2 2 2 0 Auxin canalisation Hamartin PF04388.12 CDJ48995.1 - 2.1 6.9 21.1 2.2 6.8 21.1 1.0 1 0 0 1 1 1 0 Hamartin protein CRT10 PF08728.10 CDJ48995.1 - 2.2 6.3 9.0 2.3 6.3 9.0 1.0 1 0 0 1 1 1 0 CRT10 Ribosomal_60s PF00428.19 CDJ48995.1 - 2.3 8.9 37.2 1.5 9.5 12.9 2.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein PA26 PF04636.13 CDJ48995.1 - 2.8 6.8 17.1 3.2 6.6 17.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PAT1 PF09770.9 CDJ48995.1 - 5 5.3 40.9 5.7 5.1 40.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Draxin PF15550.6 CDJ48995.1 - 5.9 6.7 24.2 7.1 6.4 24.2 1.1 1 0 0 1 1 1 0 Draxin MCM_bind PF09739.9 CDJ48995.1 - 5.9 5.2 21.7 7 5.0 21.7 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor GREB1 PF15782.5 CDJ48995.1 - 6.3 3.8 30.0 7.5 3.5 30.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer VIR_N PF15912.5 CDJ48995.1 - 6.5 6.3 15.9 8.5 5.9 15.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal ALMT PF11744.8 CDJ48995.1 - 6.5 5.5 18.8 8.4 5.1 18.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter CAML PF14963.6 CDJ48995.1 - 9.3 6.3 14.4 10 6.1 14.4 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand RskA PF10099.9 CDJ48996.1 - 1.4e-06 28.7 16.4 1.4e-06 28.7 16.4 5.2 1 1 2 5 5 5 1 Anti-sigma-K factor rskA PAT1 PF09770.9 CDJ48996.1 - 0.0017 16.7 41.9 0.0023 16.3 41.9 1.4 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Pkinase PF00069.25 CDJ48996.1 - 0.23 10.8 0.0 0.23 10.8 0.0 4.2 2 1 3 5 5 5 0 Protein kinase domain DUF2722 PF10846.8 CDJ48997.1 - 0.0034 16.4 1.0 0.0034 16.4 1.0 7.6 6 3 0 6 6 6 1 Protein of unknown function (DUF2722) DUF4667 PF15700.5 CDJ48997.1 - 0.03 14.4 0.1 0.03 14.4 0.1 6.3 5 2 0 7 7 7 0 Domain of unknown function (DUF4667) AUX_IAA PF02309.16 CDJ48997.1 - 0.17 11.7 23.9 2.5 7.9 0.0 4.9 4 1 0 4 4 4 0 AUX/IAA family SID-1_RNA_chan PF13965.6 CDJ48997.1 - 0.63 8.4 9.8 1.4 7.2 1.4 2.9 3 0 0 3 3 3 0 dsRNA-gated channel SID-1 SUI1 PF01253.22 CDJ48998.1 - 3.6e-07 30.6 0.0 9.3e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CDJ48999.1 - 1.1e-10 42.0 0.0 7.3e-10 39.4 0.0 2.3 1 1 0 1 1 1 1 Pre-PUA-like domain TMEM208_SND2 PF05620.11 CDJ48999.1 - 1.6 8.5 3.2 5.5 6.7 1.7 2.5 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Aldo_ket_red PF00248.21 CDJ49000.1 - 7e-39 133.8 0.0 3.2e-37 128.3 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family TPR_2 PF07719.17 CDJ49003.1 - 2.9e-09 36.3 6.8 0.0029 17.6 0.3 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ49003.1 - 5.4e-08 33.2 1.7 5.4e-08 33.2 1.7 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ49003.1 - 3e-07 30.0 2.5 0.0069 16.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ49003.1 - 1.2e-05 25.9 5.0 1.2e-05 25.9 5.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ49003.1 - 0.0039 17.9 0.7 0.0039 17.9 0.7 5.9 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ49003.1 - 0.0064 16.2 2.7 2.7 7.7 0.1 3.4 3 0 0 3 3 3 2 TPR repeat Fis1_TPR_C PF14853.6 CDJ49003.1 - 0.045 13.8 2.2 0.046 13.8 0.0 2.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 CDJ49003.1 - 0.11 12.5 3.0 1.5 9.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ49003.1 - 0.47 11.2 0.1 0.47 11.2 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SR-25 PF10500.9 CDJ49005.1 - 0.00088 18.9 40.3 0.001 18.8 40.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ49006.1 - 0.55 9.0 10.8 0.79 8.5 10.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 CDJ49006.1 - 4 4.4 11.7 5 4.1 11.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDJ49006.1 - 7.1 5.1 14.7 1.1 7.7 10.9 1.6 2 0 0 2 2 2 0 Macoilin family OAD_gamma PF04277.13 CDJ49006.1 - 7.3 7.3 6.9 14 6.3 2.9 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Peptidase_A22B PF04258.13 CDJ49007.1 - 1.2e-54 185.7 0.9 2e-54 185.1 0.9 1.3 1 1 0 1 1 1 1 Signal peptide peptidase DotU PF09850.9 CDJ49007.1 - 0.0033 17.2 0.1 0.01 15.5 0.1 1.8 2 0 0 2 2 2 1 Type VI secretion system protein DotU DUF2722 PF10846.8 CDJ49007.1 - 0.0036 16.3 0.1 0.0043 16.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4337 PF14235.6 CDJ49007.1 - 0.096 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SPP PF06550.11 CDJ49007.1 - 0.13 11.7 17.9 1.1 8.6 15.2 2.5 2 1 0 2 2 2 0 Signal-peptide peptidase, presenilin aspartyl protease eIF-3_zeta PF05091.12 CDJ49007.1 - 0.17 10.8 1.2 0.22 10.4 1.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Kelch_5 PF13854.6 CDJ49008.1 - 1e-10 41.4 0.2 4.7e-06 26.5 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CDJ49008.1 - 4.4e-06 26.6 0.8 0.0022 18.0 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ49008.1 - 5e-06 26.6 0.6 0.045 14.0 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CDJ49008.1 - 0.0011 19.2 20.5 0.37 11.1 0.0 7.0 8 0 0 8 8 8 2 Galactose oxidase, central domain Apt1 PF10351.9 CDJ49008.1 - 8.9 5.0 7.6 0.53 9.1 0.6 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4250 PF14056.6 CDJ49009.1 - 0.19 11.7 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) IL33 PF15095.6 CDJ49009.1 - 0.62 9.5 1.8 0.89 9.0 1.8 1.1 1 0 0 1 1 1 0 Interleukin 33 Thioredoxin_8 PF13905.6 CDJ49010.1 - 5.8e-14 52.2 0.0 9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CDJ49010.1 - 2.7e-05 24.1 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family RskA PF10099.9 CDJ49010.1 - 0.00048 20.5 5.0 0.00048 20.5 5.0 2.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Thioredoxin PF00085.20 CDJ49010.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ49010.1 - 0.0013 19.2 0.0 0.0025 18.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDJ49010.1 - 0.0013 18.8 0.3 0.0013 18.8 0.3 2.5 2 1 0 2 2 2 1 Thioredoxin-like TFIIA PF03153.13 CDJ49010.1 - 0.77 9.7 4.1 0.97 9.4 4.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PDEase_I PF00233.19 CDJ49012.1 - 6.2e-32 111.2 0.1 7.1e-32 111.0 0.1 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.19 CDJ49013.1 - 0.1 12.3 0.6 0.17 11.6 0.6 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase SOG2 PF10428.9 CDJ49013.1 - 0.19 10.9 0.9 0.21 10.7 0.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 CDJ49013.1 - 0.95 9.4 9.1 1.3 9.0 9.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PGM_PMM_III PF02880.16 CDJ49014.1 - 5.3e-09 36.3 2.3 4.9e-08 33.2 0.2 3.2 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CDJ49014.1 - 7.3e-06 26.1 3.2 7.3e-06 26.1 3.2 2.5 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SWI-SNF_Ssr4 PF08549.10 CDJ49014.1 - 6.5 5.3 11.3 0.73 8.4 5.9 1.8 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) SUIM_assoc PF16619.5 CDJ49014.1 - 6.8 6.8 21.1 0.51 10.4 10.0 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1980 PF09323.10 CDJ49015.1 - 0.017 15.0 0.1 0.017 15.0 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) EOS1 PF12326.8 CDJ49015.1 - 1.1 9.2 3.7 3.8 7.4 3.7 2.0 1 1 0 1 1 1 0 N-glycosylation protein Amb_V_allergen PF03913.13 CDJ49015.1 - 1.1 9.2 4.9 16 5.5 0.4 2.5 2 0 0 2 2 2 0 Amb V Allergen Neur_chan_memb PF02932.16 CDJ49015.1 - 3.9 7.5 7.7 1.1 9.3 0.5 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 CDJ49015.1 - 7.6 4.3 6.9 0.18 9.7 0.6 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NEMP PF10225.9 CDJ49015.1 - 8.4 6.0 8.5 0.21 11.2 0.9 1.9 2 0 0 2 2 2 0 NEMP family SR-25 PF10500.9 CDJ49018.1 - 0.0032 17.1 20.6 0.0032 17.1 20.6 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 CDJ49018.1 - 0.004 15.8 5.0 0.004 15.8 5.0 2.1 2 0 0 2 2 2 1 Macoilin family BORG_CEP PF14957.6 CDJ49018.1 - 0.011 16.9 8.5 0.018 16.2 2.1 2.4 2 0 0 2 2 2 0 Cdc42 effector DAG_kinase_N PF14513.6 CDJ49018.1 - 0.021 15.1 7.8 0.47 10.6 3.4 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus FAM76 PF16046.5 CDJ49018.1 - 0.023 14.1 15.4 0.35 10.2 0.7 2.1 2 0 0 2 2 2 0 FAM76 protein SPX PF03105.19 CDJ49018.1 - 0.059 13.3 14.2 0.11 12.5 14.2 1.3 1 0 0 1 1 1 0 SPX domain DUF4834 PF16118.5 CDJ49018.1 - 0.064 14.2 15.8 0.08 13.9 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CLN3 PF02487.17 CDJ49018.1 - 0.18 10.8 4.6 2 7.4 1.4 2.3 2 0 0 2 2 2 0 CLN3 protein FAM176 PF14851.6 CDJ49018.1 - 0.2 11.3 6.2 1.6 8.3 2.3 2.3 2 0 0 2 2 2 0 FAM176 family EPL1 PF10513.9 CDJ49018.1 - 0.2 12.0 13.1 0.45 10.9 3.2 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like GEN1_C PF18380.1 CDJ49018.1 - 0.25 12.3 5.7 2.6 9.0 0.2 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain DUF702 PF05142.12 CDJ49018.1 - 0.28 11.7 15.7 1.5 9.3 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Sarcoglycan_2 PF05510.13 CDJ49018.1 - 0.29 9.9 9.4 0.54 9.0 2.0 2.1 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon SelP_N PF04592.14 CDJ49018.1 - 0.43 10.0 24.6 0.29 10.5 18.7 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Ribosomal_60s PF00428.19 CDJ49018.1 - 0.48 11.0 26.2 2.1 9.0 6.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Tom22 PF04281.13 CDJ49018.1 - 0.64 9.8 7.0 0.34 10.7 0.5 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF1635 PF07795.11 CDJ49018.1 - 2 8.3 19.3 2.2 8.1 9.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) EOS1 PF12326.8 CDJ49018.1 - 2 8.3 5.8 5.9 6.8 1.2 2.2 2 0 0 2 2 2 0 N-glycosylation protein NST1 PF13945.6 CDJ49018.1 - 2.2 8.4 20.0 2.8 8.0 3.5 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator Apt1 PF10351.9 CDJ49018.1 - 2.3 7.0 14.9 0.21 10.4 7.6 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain Otopetrin PF03189.13 CDJ49018.1 - 2.5 6.8 5.1 3.1 6.5 2.1 1.9 2 0 0 2 2 2 0 Otopetrin Mcm10 PF09332.11 CDJ49018.1 - 2.5 7.4 22.0 0.44 9.9 7.1 2.2 2 0 0 2 2 2 0 Mcm10 replication factor Spt20 PF12090.8 CDJ49018.1 - 2.6 7.6 41.1 4.7 6.8 15.9 2.2 2 0 0 2 2 2 0 Spt20 family DUF4770 PF15994.5 CDJ49018.1 - 2.7 8.2 13.1 7.6 6.7 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) FAM60A PF15396.6 CDJ49018.1 - 3.8 7.5 12.8 1.3 9.0 4.5 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Apc15p PF05841.11 CDJ49018.1 - 4.6 8.0 24.4 2.1 9.1 8.4 2.5 2 0 0 2 2 2 0 Apc15p protein CAML PF14963.6 CDJ49018.1 - 5.7 7.0 6.2 8.1 6.5 2.5 2.2 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand PIP5K PF01504.18 CDJ49018.1 - 6 6.0 9.5 3.6 6.7 2.4 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase eIF-3_zeta PF05091.12 CDJ49018.1 - 7.6 5.4 16.9 1.9 7.4 2.3 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EBP50_C PF09007.11 CDJ49018.1 - 8.1 7.5 19.8 0.32 12.0 7.5 2.4 2 0 0 2 2 2 0 EBP50, C-terminal Connexin PF00029.19 CDJ49018.1 - 8.3 6.1 10.7 6.8 6.4 2.8 2.2 2 0 0 2 2 2 0 Connexin TCP PF03634.13 CDJ49018.1 - 8.8 6.9 20.9 4.7 7.8 9.5 2.4 2 0 0 2 2 2 0 TCP family transcription factor NEMP PF10225.9 CDJ49018.1 - 9 5.9 6.0 9.1 5.9 1.1 2.1 2 0 0 2 2 2 0 NEMP family DUF755 PF05501.11 CDJ49018.1 - 9 6.6 48.1 0.14 12.5 30.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DSPc PF00782.20 CDJ49019.1 - 0.018 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Inhibitor_I78 PF11720.8 CDJ49019.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor I78 family ZnuA PF01297.17 CDJ49022.1 - 0.052 13.0 0.1 0.15 11.5 0.1 1.8 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic BLOC1_2 PF10046.9 CDJ49022.1 - 1.9 8.8 9.1 1.9 8.9 0.1 3.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DHC_N2 PF08393.13 CDJ49023.1 - 1.8e-107 359.9 5.2 1.8e-107 359.9 5.2 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 CDJ49023.1 - 1.9e-107 359.0 0.3 1.4e-72 244.4 0.0 3.1 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_9 PF12781.7 CDJ49023.1 - 2.7e-70 235.9 0.1 1.2e-69 233.8 0.1 2.3 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 CDJ49023.1 - 5.3e-69 232.8 0.0 4.2e-68 229.8 0.0 2.5 1 1 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CDJ49023.1 - 1.3e-64 217.1 0.0 1e-60 204.4 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region DHC_N1 PF08385.12 CDJ49023.1 - 6.7e-58 196.7 6.0 1.5e-26 93.2 0.0 4.9 2 1 2 4 4 4 3 Dynein heavy chain, N-terminal region 1 MT PF12777.7 CDJ49023.1 - 1e-55 189.1 7.2 1.7e-55 188.5 7.2 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 CDJ49023.1 - 3.4e-48 164.2 0.0 9.5e-47 159.5 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 CDJ49023.1 - 4.6e-19 68.8 0.2 1.2e-15 57.7 0.1 2.6 1 1 1 2 2 2 2 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ49023.1 - 2.1e-16 60.0 0.0 8.2e-16 58.0 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ49023.1 - 1.7e-12 47.5 0.0 0.00026 21.0 0.0 5.1 3 2 2 5 5 5 2 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDJ49023.1 - 2.6e-06 27.6 9.2 0.00018 21.6 0.0 4.0 3 1 1 4 4 3 2 Dynein heavy chain AAA lid domain AAA PF00004.29 CDJ49023.1 - 9.1e-05 22.9 0.0 0.26 11.7 0.0 3.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ49023.1 - 0.00019 21.7 1.8 7.5 6.8 0.0 5.8 5 0 0 5 5 5 1 AAA domain H-kinase_dim PF02895.14 CDJ49023.1 - 0.046 14.1 2.6 17 5.9 0.0 4.2 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain RNA_helicase PF00910.22 CDJ49023.1 - 0.076 13.4 0.1 44 4.5 0.0 3.7 4 0 0 4 4 3 0 RNA helicase VIT1 PF01988.19 CDJ49023.1 - 1.4 8.7 6.8 0.53 10.1 2.4 2.5 2 0 0 2 2 2 0 VIT family DUF1451 PF07295.11 CDJ49023.1 - 3.6 7.6 9.2 0.6 10.1 0.5 4.0 3 1 0 3 3 2 0 Zinc-ribbon containing domain FlaC_arch PF05377.11 CDJ49024.1 - 4.5 7.7 5.1 53 4.3 0.1 4.9 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) zf-MYND PF01753.18 CDJ49025.1 - 3.9 7.6 7.6 33 4.7 7.6 2.8 1 1 0 1 1 1 0 MYND finger NHL PF01436.21 CDJ49026.1 - 5.4e-16 57.7 0.8 0.0049 16.8 0.0 5.6 5 0 0 5 5 5 4 NHL repeat SGL PF08450.12 CDJ49026.1 - 0.052 13.1 0.2 13 5.2 0.0 3.3 1 1 3 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region CBM_14 PF01607.24 CDJ49026.1 - 5 7.4 6.7 30 4.9 0.2 3.5 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain DUF2299 PF10061.9 CDJ49027.1 - 0.078 12.7 0.8 0.39 10.4 0.8 2.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) DUF1488 PF07369.11 CDJ49027.1 - 0.59 10.2 9.7 9.2 6.3 1.3 4.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) Pkinase PF00069.25 CDJ49028.1 - 3.8e-32 111.7 0.0 1.2e-29 103.5 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ49028.1 - 1.1e-16 60.9 0.0 7.4e-15 54.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDJ49028.1 - 0.00044 20.3 5.8 0.00099 19.1 5.8 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ49028.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Sporozoite_P67 PF05642.11 CDJ49029.1 - 0.42 8.6 11.2 0.56 8.2 10.0 1.7 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Endostatin PF06482.11 CDJ49029.1 - 9.9 5.5 32.5 0.16 11.4 13.2 3.3 3 0 0 3 3 3 0 Collagenase NC10 and Endostatin Abhydro_lipase PF04083.16 CDJ49030.1 - 1.4e-07 31.0 0.0 5.2e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CDJ49030.1 - 0.14 11.8 8.2 0.67 9.5 0.1 3.7 3 2 0 3 3 3 0 alpha/beta hydrolase fold PGA_cap PF09587.10 CDJ49030.1 - 6 6.2 8.2 1.7 8.0 2.3 2.6 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap Peptidase_S49_N PF08496.10 CDJ49032.1 - 3.2 7.8 5.7 5.5 7.0 5.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3395 PF11875.8 CDJ49032.1 - 5 7.0 7.6 9.3 6.1 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Peptidase_M14 PF00246.24 CDJ49033.1 - 3.4e-08 33.7 0.0 0.014 15.2 0.0 3.0 2 1 0 2 2 2 2 Zinc carboxypeptidase SUZ PF12752.7 CDJ49033.1 - 1.2 9.9 7.9 1.7 9.5 1.9 3.5 2 0 0 2 2 2 0 SUZ domain CCSAP PF15748.5 CDJ49033.1 - 2.8 8.1 34.3 0.23 11.6 3.1 4.4 4 0 0 4 4 4 0 Centriole, cilia and spindle-associated Hist_deacetyl PF00850.19 CDJ49033.1 - 6.5 6.1 7.9 25 4.2 0.8 3.2 3 0 0 3 3 3 0 Histone deacetylase domain CRT-like PF08627.10 CDJ49034.1 - 3.3e-08 32.9 1.2 1e-07 31.3 0.2 1.9 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like SDA1 PF05285.12 CDJ49034.1 - 0.032 13.7 35.6 0.0064 16.0 14.1 2.2 2 0 0 2 2 2 0 SDA1 EamA PF00892.20 CDJ49034.1 - 0.23 11.6 5.9 0.55 10.4 5.9 1.6 1 0 0 1 1 1 0 EamA-like transporter family PUNUT PF16913.5 CDJ49034.1 - 0.45 9.7 8.7 0.25 10.5 3.5 2.5 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport Shadoo PF14999.6 CDJ49034.1 - 3.9 7.6 13.7 29 4.8 0.0 3.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF2722 PF10846.8 CDJ49035.1 - 0.0033 16.4 13.8 0.0033 16.4 13.8 5.1 5 1 0 5 5 5 2 Protein of unknown function (DUF2722) DUF1980 PF09323.10 CDJ49035.1 - 7 6.5 21.4 0.37 10.7 1.6 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) TFIIA PF03153.13 CDJ49036.1 - 0.00016 21.8 20.4 0.0002 21.5 20.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GNAT_acetyltr_2 PF13718.6 CDJ49036.1 - 0.012 15.1 2.1 0.021 14.2 2.1 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF3446 PF11928.8 CDJ49036.1 - 0.019 15.2 5.7 0.019 15.2 5.7 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain SLD3 PF08639.10 CDJ49036.1 - 0.061 12.1 8.8 0.047 12.4 7.0 1.6 2 0 0 2 2 2 0 DNA replication regulator SLD3 SR-25 PF10500.9 CDJ49036.1 - 0.36 10.4 24.7 0.021 14.4 7.5 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Rotamase_2 PF13145.6 CDJ49036.1 - 0.81 10.5 11.5 0.67 10.8 3.6 2.2 2 0 0 2 2 2 0 PPIC-type PPIASE domain Spt20 PF12090.8 CDJ49036.1 - 2.5 7.6 27.0 0.53 9.9 23.5 1.7 2 0 0 2 2 2 0 Spt20 family eIF-3_zeta PF05091.12 CDJ49036.1 - 3.6 6.5 14.3 5 6.0 14.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4638 PF15472.6 CDJ49036.1 - 3.7 7.2 13.0 7.1 6.3 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Connexin PF00029.19 CDJ49036.1 - 4.3 7.0 8.4 8.2 6.1 8.4 1.4 1 0 0 1 1 1 0 Connexin Peptidase_S49_N PF08496.10 CDJ49036.1 - 4.7 7.3 13.6 2.3 8.3 10.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Hid1 PF12722.7 CDJ49036.1 - 4.9 5.1 8.0 7 4.6 8.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ATC_hydrolase PF14196.6 CDJ49036.1 - 6.7 7.5 8.0 0.99 10.2 1.2 2.1 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Tim54 PF11711.8 CDJ49036.1 - 9.3 4.9 11.7 3.9 6.2 8.8 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 MAT1 PF06391.13 CDJ49036.1 - 9.7 6.0 18.7 1.1 9.1 14.3 1.6 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 RAP1 PF07218.11 CDJ49037.1 - 0.0025 16.2 4.2 0.0027 16.1 4.2 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) DUF4175 PF13779.6 CDJ49037.1 - 0.035 12.0 34.2 0.041 11.8 34.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.13 CDJ49037.1 - 0.054 13.5 47.0 0.082 12.9 47.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Maf PF02545.14 CDJ49037.1 - 0.057 13.3 5.5 0.11 12.3 5.4 1.8 1 1 0 1 1 1 0 Maf-like protein VIT1 PF01988.19 CDJ49037.1 - 0.1 12.5 8.5 0.25 11.2 8.5 1.6 1 0 0 1 1 1 0 VIT family DUF4207 PF13904.6 CDJ49037.1 - 0.2 11.3 39.0 0.049 13.3 18.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) SOBP PF15279.6 CDJ49037.1 - 0.88 10.1 24.6 1.1 9.8 24.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein FUSC PF04632.12 CDJ49037.1 - 1 7.8 16.9 1.1 7.7 16.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3381 PF11861.8 CDJ49037.1 - 1.4 8.7 21.5 0.79 9.5 9.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Lin-8 PF03353.15 CDJ49037.1 - 3.9 6.9 36.5 0.17 11.4 2.4 2.1 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist DDRGK PF09756.9 CDJ49037.1 - 4.7 6.8 25.7 1 8.9 10.7 2.1 2 0 0 2 2 2 0 DDRGK domain O-antigen_lig PF13425.6 CDJ49037.1 - 5.1 5.8 5.4 6.8 5.4 5.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DivIC PF04977.15 CDJ49037.1 - 5.7 6.8 34.0 6.8 6.5 13.5 2.2 2 0 0 2 2 2 0 Septum formation initiator PAT1 PF09770.9 CDJ49037.1 - 7.7 4.6 32.9 9.7 4.3 32.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ49038.1 - 2.4 7.7 50.3 0.068 12.8 33.8 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ49039.1 - 3.6e-05 22.1 21.4 4.3e-05 21.9 21.4 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein RRF PF01765.19 CDJ49039.1 - 0.0023 17.9 0.3 0.0038 17.2 0.3 1.3 1 0 0 1 1 1 1 Ribosome recycling factor CCDC106 PF15794.5 CDJ49039.1 - 0.2 11.3 14.3 0.35 10.5 4.5 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 Trp_oprn_chp PF09534.10 CDJ49039.1 - 0.22 11.3 5.9 0.1 12.4 1.9 2.1 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pol_alpha_B_N PF08418.10 CDJ49039.1 - 1.1 9.1 11.8 3.2 7.7 3.2 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Peptidase_S64 PF08192.11 CDJ49039.1 - 1.6 7.1 11.2 2.3 6.6 11.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 RAP1 PF07218.11 CDJ49039.1 - 1.7 6.9 7.5 1.6 6.9 7.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Miga PF10265.9 CDJ49039.1 - 2.2 7.1 8.5 2.9 6.8 8.5 1.2 1 0 0 1 1 1 0 Mitoguardin Mlh1_C PF16413.5 CDJ49039.1 - 5 6.4 9.4 0.057 12.8 1.3 1.8 3 0 0 3 3 3 0 DNA mismatch repair protein Mlh1 C-terminus SR-25 PF10500.9 CDJ49041.1 - 0.0008 19.1 1.6 0.0008 19.1 1.6 2.2 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein ELO PF01151.18 CDJ49043.1 - 4.4e-47 160.7 16.7 4.4e-47 160.7 16.7 1.9 2 1 0 2 2 2 1 GNS1/SUR4 family PI3_PI4_kinase PF00454.27 CDJ49045.1 - 3.2e-24 86.1 0.0 1.3e-21 77.5 0.0 2.8 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4064 PF13273.6 CDJ49046.1 - 0.48 10.7 5.4 0.54 10.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) EphA2_TM PF14575.6 CDJ49046.1 - 7.1 7.6 9.8 3.3 8.7 0.9 3.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain SUIM_assoc PF16619.5 CDJ49047.1 - 0.0014 18.7 14.1 0.0014 18.7 14.1 2.4 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF2921 PF11145.8 CDJ49047.1 - 0.0061 14.5 1.2 0.0081 14.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) DUF2721 PF11026.8 CDJ49047.1 - 0.02 14.7 5.4 0.6 10.0 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) TFIIA PF03153.13 CDJ49047.1 - 0.031 14.3 23.8 0.04 13.9 23.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1980 PF09323.10 CDJ49047.1 - 0.039 13.9 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Neur_chan_memb PF02932.16 CDJ49047.1 - 0.1 12.7 2.0 0.12 12.4 2.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 CDJ49047.1 - 0.23 10.3 20.1 0.072 12.0 12.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) ABC2_membrane_2 PF12679.7 CDJ49047.1 - 0.24 10.7 1.5 0.85 8.8 1.5 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein CCDC53 PF10152.9 CDJ49047.1 - 0.36 11.2 9.3 0.67 10.4 9.3 1.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF1180 PF06679.12 CDJ49047.1 - 0.69 10.3 9.7 1.3 9.5 9.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Pex14_N PF04695.13 CDJ49047.1 - 0.8 10.3 22.7 3.3 8.3 22.7 1.8 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.12 CDJ49047.1 - 0.95 8.4 9.6 1.2 8.0 9.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ49047.1 - 1.5 7.5 6.6 1.8 7.2 6.6 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CDJ49047.1 - 1.7 6.7 5.1 2 6.5 5.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Conotoxin PF02950.17 CDJ49047.1 - 2 9.5 7.8 9.3 7.4 0.5 2.3 2 0 0 2 2 2 0 Conotoxin Ctr PF04145.15 CDJ49047.1 - 5.1 7.7 10.9 55 4.3 10.9 2.0 1 1 0 1 1 1 0 Ctr copper transporter family DivIC PF04977.15 CDJ49047.1 - 5.3 6.9 19.7 3.7 7.4 1.9 2.2 2 0 0 2 2 2 0 Septum formation initiator Beta-Casp PF10996.8 CDJ49048.1 - 0.00012 22.3 0.0 0.0016 18.7 0.0 2.8 3 0 0 3 3 3 1 Beta-Casp domain TFIIA PF03153.13 CDJ49048.1 - 0.0047 17.0 28.2 0.0047 17.0 28.2 4.7 2 2 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit Lactamase_B_6 PF16661.5 CDJ49048.1 - 0.086 12.3 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain Utp14 PF04615.13 CDJ49048.1 - 0.4 9.2 22.6 0.72 8.4 14.5 2.5 2 0 0 2 2 2 0 Utp14 protein Tmemb_14 PF03647.13 CDJ49049.1 - 1.3e-07 32.3 5.5 2.6e-07 31.3 5.5 1.8 1 1 0 1 1 1 1 Transmembrane proteins 14C DUF3824 PF12868.7 CDJ49049.1 - 0.019 15.6 3.9 0.019 15.6 3.9 2.5 1 1 2 3 3 3 0 Domain of unknwon function (DUF3824) Spt20 PF12090.8 CDJ49049.1 - 0.06 12.9 9.3 0.065 12.8 9.3 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ49049.1 - 0.18 11.8 13.3 0.2 11.6 13.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VIT1 PF01988.19 CDJ49049.1 - 0.32 10.9 10.0 0.45 10.3 10.0 1.4 1 1 0 1 1 1 0 VIT family DUF2722 PF10846.8 CDJ49049.1 - 0.65 8.9 8.3 0.78 8.6 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF202 PF02656.15 CDJ49049.1 - 1.7 9.1 6.7 2.6 8.5 4.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF212 PF02681.14 CDJ49049.1 - 2.4 8.3 10.0 1.5 8.9 1.1 2.1 1 1 1 2 2 2 0 Divergent PAP2 family Med15 PF09606.10 CDJ49049.1 - 9.5 4.8 20.5 11 4.6 20.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM76 PF16046.5 CDJ49050.1 - 0.01 15.2 12.6 0.0089 15.4 12.6 1.1 1 0 0 1 1 1 0 FAM76 protein SpoIIP PF07454.11 CDJ49050.1 - 0.022 14.2 12.8 0.019 14.4 12.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 CDJ49050.1 - 0.025 12.9 9.7 0.022 13.1 9.7 1.0 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 CDJ49050.1 - 0.036 12.9 10.1 0.029 13.2 10.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ49050.1 - 0.064 12.0 17.3 0.057 12.2 17.3 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ49050.1 - 0.074 12.1 12.5 0.064 12.3 12.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 CDJ49050.1 - 0.15 12.0 8.7 0.13 12.2 8.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A ALMT PF11744.8 CDJ49050.1 - 0.21 10.4 10.1 0.2 10.4 10.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Band_3_cyto PF07565.13 CDJ49050.1 - 0.28 11.0 13.1 0.26 11.1 13.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S64 PF08192.11 CDJ49050.1 - 0.34 9.4 10.7 0.28 9.6 10.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 MDM10 PF12519.8 CDJ49050.1 - 0.42 9.4 12.5 0.37 9.6 12.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 ABC2_membrane_2 PF12679.7 CDJ49050.1 - 0.57 9.4 3.8 0.7 9.1 3.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Cellulose_synt PF03552.14 CDJ49050.1 - 0.61 8.5 2.6 0.58 8.6 2.6 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF4746 PF15928.5 CDJ49050.1 - 0.62 9.4 15.1 0.64 9.4 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Otopetrin PF03189.13 CDJ49050.1 - 0.62 8.8 7.7 0.51 9.1 7.7 1.1 1 0 0 1 1 1 0 Otopetrin NST1 PF13945.6 CDJ49050.1 - 0.69 10.0 25.2 0.025 14.7 19.9 1.3 2 0 0 2 2 1 0 Salt tolerance down-regulator FemAB PF02388.16 CDJ49050.1 - 0.79 8.5 14.6 0.7 8.7 14.6 1.1 1 0 0 1 1 1 0 FemAB family Tim54 PF11711.8 CDJ49050.1 - 0.91 8.2 16.1 0.88 8.3 16.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM91_C PF14648.6 CDJ49050.1 - 1.1 8.0 6.6 1.1 8.0 6.6 1.1 1 0 0 1 1 1 0 FAM91 C-terminus XRN_M PF17846.1 CDJ49050.1 - 1.2 8.0 9.4 1.2 8.1 9.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain OATP PF03137.20 CDJ49050.1 - 1.5 7.0 7.1 1.4 7.1 7.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Hid1 PF12722.7 CDJ49050.1 - 1.8 6.6 14.7 1.4 6.9 14.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Paramyxo_ncap PF00973.19 CDJ49050.1 - 2.1 7.2 10.3 2.1 7.2 10.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Lin-8 PF03353.15 CDJ49050.1 - 2.8 7.4 22.2 2.8 7.4 22.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CTU2 PF10288.9 CDJ49050.1 - 8.1 6.7 15.2 4.3 7.6 13.2 1.7 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF913 PF06025.12 CDJ49050.1 - 9.9 5.0 11.4 10 5.0 11.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tfb4 PF03850.14 CDJ49051.1 - 0.044 13.3 5.2 0.095 12.2 5.2 1.5 1 0 0 1 1 1 0 Transcription factor Tfb4 OATP PF03137.20 CDJ49051.1 - 0.45 8.7 2.9 0.67 8.2 2.9 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AMPKBI PF04739.15 CDJ49051.1 - 0.71 10.2 4.7 2 8.7 4.7 1.9 1 1 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain Tam41_Mmp37 PF09139.11 CDJ49051.1 - 1.1 8.6 10.4 1.6 8.1 10.4 1.4 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial PAT1 PF09770.9 CDJ49051.1 - 1.3 7.2 35.8 1.7 6.8 35.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ49051.1 - 2.1 5.4 14.9 2.5 5.1 14.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM60A PF15396.6 CDJ49051.1 - 3.5 7.6 5.5 6 6.8 5.5 1.4 1 0 0 1 1 1 0 Protein Family FAM60A RskA PF10099.9 CDJ49054.1 - 3.4e-05 24.2 56.5 0.00043 20.6 0.5 4.2 1 1 3 4 4 4 3 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ49054.1 - 0.00018 21.9 4.1 2.7 8.5 0.1 3.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4179) GT87 PF09594.10 CDJ49054.1 - 0.0025 17.6 1.1 0.0048 16.6 1.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 87 SR-25 PF10500.9 CDJ49054.1 - 0.0096 15.5 14.3 0.0096 15.5 14.3 3.5 2 2 1 3 3 3 2 Nuclear RNA-splicing-associated protein Shadoo PF14999.6 CDJ49054.1 - 0.014 15.4 10.7 0.76 9.9 0.1 2.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF4205 PF13898.6 CDJ49055.1 - 4.6e-09 35.7 4.4 4.6e-09 35.7 4.4 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4205) DUF2722 PF10846.8 CDJ49055.1 - 0.00079 18.5 31.3 0.024 13.6 4.9 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ49055.1 - 0.0077 15.0 42.8 0.015 14.0 20.5 2.3 2 1 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ49055.1 - 0.032 13.8 41.0 0.1 12.2 8.2 3.1 3 0 0 3 3 3 0 Spt20 family FAM176 PF14851.6 CDJ49055.1 - 0.66 9.6 9.8 0.36 10.5 0.1 2.8 3 0 0 3 3 3 0 FAM176 family DUF4834 PF16118.5 CDJ49055.1 - 0.97 10.4 17.3 0.42 11.6 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3371 PF11851.8 CDJ49055.1 - 7.6 7.6 31.6 1.7 9.7 1.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3371) Mit_KHE1 PF10173.9 CDJ49056.1 - 0.94 9.5 11.5 4.3 7.4 7.4 2.4 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Peptidase_M56 PF05569.11 CDJ49056.1 - 3.7 6.7 8.4 21 4.2 0.1 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 Ribosomal_60s PF00428.19 CDJ49056.1 - 4.5 7.9 16.7 16 6.2 12.5 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein IHABP4_N PF16174.5 CDJ49056.1 - 4.8 7.8 37.4 0.82 10.3 0.9 2.7 2 1 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal CLN3 PF02487.17 CDJ49056.1 - 8.7 5.3 13.8 11 4.9 8.2 2.2 2 0 0 2 2 2 0 CLN3 protein BAF1_ABF1 PF04684.13 CDJ49058.1 - 0.12 11.4 32.1 0.13 11.2 32.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PvlArgDC PF01862.16 CDJ49058.1 - 1.2 8.9 6.3 1.6 8.5 6.3 1.3 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Apt1 PF10351.9 CDJ49058.1 - 6.6 5.5 30.0 7 5.4 30.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SARAF PF06682.12 CDJ49058.1 - 9.6 5.7 32.7 10 5.6 32.7 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis ARS2 PF04959.13 CDJ49059.1 - 1.2 9.5 12.5 0.9 9.9 8.0 2.2 2 0 0 2 2 2 0 Arsenite-resistance protein 2 DUF2722 PF10846.8 CDJ49060.1 - 0.0009 18.3 10.9 0.0009 18.3 10.9 13.2 4 2 5 10 10 10 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ49061.1 - 0.011 15.3 8.8 0.013 15.1 8.8 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ49061.1 - 0.012 15.7 6.0 0.012 15.7 6.0 2.2 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 CDJ49061.1 - 0.017 15.5 1.0 0.022 15.2 1.0 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Methyltransf_34 PF11312.8 CDJ49061.1 - 0.044 13.0 5.0 0.057 12.6 5.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Ago_N_1 PF18351.1 CDJ49061.1 - 0.13 12.7 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Fungal Argonaute N-terminal domain Nop53 PF07767.11 CDJ49061.1 - 0.3 10.4 9.3 0.38 10.1 9.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIA PF03153.13 CDJ49061.1 - 0.6 10.0 16.1 0.71 9.8 16.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ49061.1 - 7.6 5.5 10.9 9.1 5.3 10.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Pex14_N PF04695.13 CDJ49062.1 - 0.031 14.9 23.8 0.036 14.7 23.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.22 CDJ49062.1 - 0.042 13.1 15.0 0.052 12.8 15.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Tfb4 PF03850.14 CDJ49062.1 - 0.17 11.4 9.3 0.2 11.2 9.3 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 Velvet PF11754.8 CDJ49062.1 - 0.22 11.4 18.5 0.25 11.2 18.5 1.0 1 0 0 1 1 1 0 Velvet factor eIF3_subunit PF08597.10 CDJ49062.1 - 0.23 11.3 28.5 0.26 11.2 28.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Suf PF05843.14 CDJ49062.1 - 0.25 11.3 24.0 0.29 11.1 24.0 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ASC PF00858.24 CDJ49062.1 - 0.35 9.8 13.0 0.41 9.6 13.0 1.0 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF4407 PF14362.6 CDJ49062.1 - 0.37 10.1 24.8 0.44 9.9 24.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gti1_Pac2 PF09729.9 CDJ49062.1 - 0.45 10.6 21.2 0.5 10.4 21.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family TRAP_alpha PF03896.16 CDJ49062.1 - 0.45 9.7 10.2 0.57 9.3 10.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Vfa1 PF08432.10 CDJ49062.1 - 0.6 10.4 29.3 0.74 10.1 29.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TFIIA PF03153.13 CDJ49062.1 - 0.61 10.0 36.1 0.77 9.7 36.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ49062.1 - 0.65 9.8 29.6 0.76 9.6 29.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MCM_bind PF09739.9 CDJ49062.1 - 0.75 8.2 23.3 0.82 8.1 23.3 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF5427 PF10310.9 CDJ49062.1 - 0.78 8.6 29.7 0.94 8.4 29.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) NPR3 PF03666.13 CDJ49062.1 - 1 8.1 28.9 1.2 7.9 28.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Rtf2 PF04641.12 CDJ49062.1 - 1 8.7 27.8 1.2 8.4 27.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger FAM60A PF15396.6 CDJ49062.1 - 1.4 8.9 23.2 1.6 8.7 23.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Ocular_alb PF02101.15 CDJ49062.1 - 1.4 7.7 4.4 1.6 7.6 4.4 1.2 1 0 0 1 1 1 0 Ocular albinism type 1 protein CCDC53 PF10152.9 CDJ49062.1 - 1.7 9.0 19.5 2.4 8.5 19.5 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Kei1 PF08552.11 CDJ49062.1 - 1.8 8.4 12.7 2.2 8.1 12.7 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Presenilin PF01080.17 CDJ49062.1 - 2.6 6.7 30.7 2.8 6.6 30.7 1.0 1 0 0 1 1 1 0 Presenilin DUF2126 PF09899.9 CDJ49062.1 - 2.8 5.9 14.3 3 5.8 14.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Endostatin PF06482.11 CDJ49062.1 - 2.9 7.3 18.5 3.3 7.1 18.5 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Pox_Ag35 PF03286.14 CDJ49062.1 - 3 7.6 22.6 3.6 7.3 22.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FemAB PF02388.16 CDJ49062.1 - 3.7 6.3 22.8 4.7 6.0 22.8 1.0 1 0 0 1 1 1 0 FemAB family DUF2370 PF10176.9 CDJ49062.1 - 3.7 7.1 11.5 4.1 7.0 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) PepSY_TM PF03929.16 CDJ49062.1 - 4 7.0 6.2 4.2 6.9 6.2 1.3 1 0 0 1 1 1 0 PepSY-associated TM region ALMT PF11744.8 CDJ49062.1 - 4.3 6.1 19.9 4.8 5.9 19.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2151 PF10221.9 CDJ49062.1 - 5 5.6 17.9 5.1 5.6 17.9 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Peptidase_S64 PF08192.11 CDJ49062.1 - 6.1 5.2 21.5 6.3 5.2 21.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 HCO3_cotransp PF00955.21 CDJ49062.1 - 6.4 5.5 8.8 7.2 5.3 8.8 1.0 1 0 0 1 1 1 0 HCO3- transporter family MAJIN PF15077.6 CDJ49062.1 - 7 6.4 23.8 7.7 6.2 23.8 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein PAT1 PF09770.9 CDJ49062.1 - 7.1 4.8 29.8 7.5 4.7 29.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dsh_C PF12316.8 CDJ49062.1 - 7.1 7.0 15.6 8 6.8 15.6 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF913 PF06025.12 CDJ49062.1 - 7.7 5.4 17.1 9.2 5.1 17.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4569 PF15133.6 CDJ49062.1 - 8.6 6.0 24.9 9.6 5.8 24.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) SLC12 PF03522.15 CDJ49062.1 - 8.6 5.3 26.3 9.8 5.1 26.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 CDJ49062.1 - 9.2 4.4 30.5 11 4.2 30.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Paramyxo_ncap PF00973.19 CDJ49062.1 - 9.6 5.0 21.0 9.9 4.9 21.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Raftlin PF15250.6 CDJ49062.1 - 9.7 4.8 20.8 11 4.7 20.8 1.0 1 0 0 1 1 1 0 Raftlin Rrn6 PF10214.9 CDJ49062.1 - 9.7 4.5 28.2 11 4.4 28.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TFIIA PF03153.13 CDJ49063.1 - 0.16 12.0 15.9 0.18 11.7 15.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FleQ PF06490.11 CDJ49063.1 - 4.4 7.7 6.4 3.4 8.1 0.9 2.1 1 1 1 2 2 2 0 Flagellar regulatory protein FleQ DrsE PF02635.15 CDJ49063.1 - 5.9 7.3 14.3 4.2 7.8 3.1 2.7 1 1 1 2 2 2 0 DsrE/DsrF-like family GREB1 PF15782.5 CDJ49063.1 - 7.8 3.5 10.6 9 3.3 10.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EF-hand_6 PF13405.6 CDJ49064.1 - 6.7e-07 28.7 0.1 1.1e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CDJ49064.1 - 1.1e-06 27.8 0.1 1.6e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CDJ49064.1 - 0.0007 20.0 0.0 0.001 19.5 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ49064.1 - 0.00083 18.8 0.1 0.0013 18.2 0.1 1.2 1 0 0 1 1 1 1 EF hand Caleosin PF05042.13 CDJ49064.1 - 0.0066 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Caleosin related protein EF-hand_8 PF13833.6 CDJ49064.1 - 0.0082 16.0 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair SUIM_assoc PF16619.5 CDJ49064.1 - 0.023 14.7 0.2 0.023 14.7 0.2 4.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ49065.1 - 0.01 14.8 21.2 0.01 14.8 21.2 5.1 3 1 2 5 5 5 0 Protein of unknown function (DUF2722) Macoilin PF09726.9 CDJ49066.1 - 0.047 12.3 0.2 0.056 12.0 0.2 1.2 1 0 0 1 1 1 0 Macoilin family DUF1387 PF07139.11 CDJ49067.1 - 0.62 9.7 25.4 0.74 9.5 25.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF2722 PF10846.8 CDJ49067.1 - 1.5 7.6 47.9 0.2 10.6 6.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) PRP1_N PF06424.12 CDJ49067.1 - 4.6 7.6 24.9 0.66 10.4 11.3 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Peroxin-3 PF04882.12 CDJ49067.1 - 6.7 5.6 23.1 11 4.9 23.1 1.3 1 0 0 1 1 1 0 Peroxin-3 Peptidase_S49_N PF08496.10 CDJ49067.1 - 9 6.3 18.0 1.1 9.3 7.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SelP_N PF04592.14 CDJ49067.1 - 9.8 5.5 20.1 0.28 10.6 11.3 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Ribosomal_L17 PF01196.19 CDJ49068.1 - 3.3e-20 72.8 0.1 5.9e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 Presenilin PF01080.17 CDJ49070.1 - 0.012 14.4 19.4 0.016 14.0 19.4 1.1 1 0 0 1 1 1 0 Presenilin TMEM247 PF15444.6 CDJ49070.1 - 0.023 14.7 4.7 0.027 14.5 4.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 TFIIA PF03153.13 CDJ49070.1 - 0.088 12.8 38.7 0.092 12.7 38.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4207 PF13904.6 CDJ49070.1 - 0.13 12.0 26.1 0.18 11.5 26.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Med15 PF09606.10 CDJ49070.1 - 0.14 10.9 28.8 0.17 10.6 28.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Velvet PF11754.8 CDJ49070.1 - 0.14 12.0 13.7 0.21 11.5 13.7 1.3 1 0 0 1 1 1 0 Velvet factor MTBP_C PF14920.6 CDJ49070.1 - 0.15 11.8 17.3 0.18 11.6 17.3 1.2 1 0 0 1 1 1 0 MDM2-binding Rtf2 PF04641.12 CDJ49070.1 - 0.16 11.3 14.5 0.22 10.9 14.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger PPP4R2 PF09184.11 CDJ49070.1 - 0.17 11.5 7.6 0.18 11.4 7.6 1.0 1 0 0 1 1 1 0 PPP4R2 DUF572 PF04502.13 CDJ49070.1 - 0.25 10.9 15.1 0.27 10.8 15.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RskA PF10099.9 CDJ49070.1 - 0.3 11.4 37.3 3.1e+02 1.5 37.3 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RR_TM4-6 PF06459.12 CDJ49070.1 - 0.59 9.9 14.4 0.68 9.7 14.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ49070.1 - 0.59 10.1 12.5 0.77 9.7 12.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.9 CDJ49070.1 - 1.4 7.1 21.9 1.3 7.2 21.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Serinc PF03348.15 CDJ49070.1 - 1.8 7.4 8.8 2.2 7.1 8.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) eIF-3_zeta PF05091.12 CDJ49070.1 - 1.9 7.3 16.9 2.5 7.0 16.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GREB1 PF15782.5 CDJ49070.1 - 2.1 5.4 19.1 2 5.4 19.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Suf PF05843.14 CDJ49070.1 - 2.7 7.9 21.6 3.5 7.5 21.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Het-C PF07217.11 CDJ49070.1 - 3.4 6.1 8.5 3.6 6.0 8.5 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Hid1 PF12722.7 CDJ49070.1 - 3.7 5.6 16.1 4.2 5.4 16.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC27 PF09507.10 CDJ49070.1 - 3.9 6.8 24.5 4.5 6.6 24.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 CDJ49070.1 - 4.2 5.9 17.7 4.4 5.9 17.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HAUS6_N PF14661.6 CDJ49070.1 - 4.7 6.7 15.7 5.6 6.5 15.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Neur_chan_memb PF02932.16 CDJ49070.1 - 5.9 6.9 13.4 8.1 6.4 13.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MAJIN PF15077.6 CDJ49070.1 - 6.3 6.5 13.0 8 6.2 13.0 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Smg8_Smg9 PF10220.9 CDJ49070.1 - 7 4.8 16.8 7.9 4.6 16.8 1.0 1 0 0 1 1 1 0 Smg8_Smg9 NEMP PF10225.9 CDJ49070.1 - 7.2 6.2 7.8 10 5.7 7.8 1.2 1 0 0 1 1 1 0 NEMP family DUF4551 PF15087.6 CDJ49070.1 - 9.2 5.0 18.6 11 4.7 18.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Tim54 PF11711.8 CDJ49071.1 - 4.2 6.0 20.0 5.4 5.7 20.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop53 PF07767.11 CDJ49071.1 - 5.7 6.2 31.0 6.1 6.1 31.0 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Presenilin PF01080.17 CDJ49071.1 - 6.4 5.4 26.2 6.5 5.4 26.2 1.0 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.12 CDJ49071.1 - 7.1 5.9 18.1 8.1 5.7 18.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2398 PF09661.10 CDJ49073.1 - 0.0072 15.6 0.0 0.0097 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2398) SR-25 PF10500.9 CDJ49074.1 - 0.021 14.4 18.0 0.11 12.1 0.6 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3246 PF11596.8 CDJ49074.1 - 0.027 13.9 0.7 0.073 12.5 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) UQ_con PF00179.26 CDJ49075.1 - 2.2e-07 30.6 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4813 PF16072.5 CDJ49075.1 - 0.00047 19.9 24.9 0.00061 19.5 24.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4813) RWD PF05773.22 CDJ49075.1 - 0.0055 17.0 0.0 0.0072 16.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain SurA_N_3 PF13624.6 CDJ49076.1 - 0.00012 21.9 15.7 0.00016 21.5 15.7 1.1 1 0 0 1 1 1 1 SurA N-terminal domain SID-1_RNA_chan PF13965.6 CDJ49076.1 - 0.00078 18.0 3.8 0.00092 17.7 3.8 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DUF3810 PF12725.7 CDJ49076.1 - 0.0012 18.3 5.5 0.0015 18.0 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) HemX PF04375.14 CDJ49076.1 - 0.004 16.5 24.8 0.0045 16.3 24.8 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase MMM1 PF10296.9 CDJ49076.1 - 0.0058 15.7 4.7 0.0082 15.2 4.7 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Neur_chan_memb PF02932.16 CDJ49076.1 - 0.01 16.0 2.3 0.011 15.8 2.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4330 PF14221.6 CDJ49076.1 - 0.012 15.9 1.2 0.015 15.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) CLN3 PF02487.17 CDJ49076.1 - 0.023 13.8 4.1 0.031 13.3 4.1 1.3 1 0 0 1 1 1 0 CLN3 protein O-antigen_lig PF13425.6 CDJ49076.1 - 0.027 13.3 3.0 0.033 13.0 3.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Zip PF02535.22 CDJ49076.1 - 0.052 12.8 0.3 0.063 12.5 0.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 CDJ49076.1 - 0.066 11.1 8.7 0.079 10.9 8.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FtsH_ext PF06480.15 CDJ49076.1 - 0.14 12.6 1.3 0.18 12.2 1.3 1.3 1 0 0 1 1 1 0 FtsH Extracellular Serinc PF03348.15 CDJ49076.1 - 0.18 10.7 2.8 0.23 10.3 2.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.17 CDJ49076.1 - 0.19 11.9 7.0 0.22 11.7 7.0 1.1 1 0 0 1 1 1 0 DDHD domain Pex24p PF06398.11 CDJ49076.1 - 0.33 9.9 1.7 0.31 10.0 0.9 1.4 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin TFIIA PF03153.13 CDJ49076.1 - 0.38 10.7 30.4 0.41 10.6 30.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4471 PF14740.6 CDJ49076.1 - 0.39 9.9 11.2 0.48 9.6 11.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) CSG2 PF16965.5 CDJ49076.1 - 0.46 9.4 2.5 0.52 9.2 2.5 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator CemA PF03040.14 CDJ49076.1 - 0.99 9.3 10.0 1.2 9.0 10.0 1.1 1 0 0 1 1 1 0 CemA family DNA_primase_lrg PF04104.14 CDJ49076.1 - 1.1 8.6 10.6 1.3 8.3 10.6 1.0 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit DUF4446 PF14584.6 CDJ49076.1 - 1.3 9.0 11.3 5.2 7.0 11.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3708 PF12501.8 CDJ49076.1 - 1.3 8.8 4.1 1.6 8.5 4.1 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter YjbH PF06082.11 CDJ49076.1 - 1.7 7.4 13.4 1.9 7.2 13.4 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH SurA_N_2 PF13623.6 CDJ49076.1 - 2.3 8.1 30.8 18 5.2 30.8 1.9 1 1 0 1 1 1 0 SurA N-terminal domain DUF4834 PF16118.5 CDJ49077.1 - 1.7e-05 25.7 7.1 1.7e-05 25.7 7.1 2.3 1 1 1 2 2 1 1 Domain of unknown function (DUF4834) RskA PF10099.9 CDJ49077.1 - 2e-05 25.0 3.2 2e-05 25.0 3.2 2.1 1 1 0 2 2 2 1 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ49077.1 - 0.00046 19.1 23.3 0.00058 18.7 23.3 1.2 1 0 0 1 1 1 1 Presenilin G0-G1_switch_2 PF15103.6 CDJ49077.1 - 0.00093 19.6 13.8 0.0037 17.7 0.8 2.2 2 0 0 2 2 2 1 G0/G1 switch protein 2 Macoilin PF09726.9 CDJ49077.1 - 0.01 14.5 20.5 0.013 14.1 20.5 1.2 1 0 0 1 1 1 0 Macoilin family Spt20 PF12090.8 CDJ49077.1 - 0.014 15.0 63.8 0.29 10.7 27.7 2.1 2 0 0 2 2 2 0 Spt20 family DUF5327 PF17261.2 CDJ49077.1 - 0.018 15.7 25.7 0.076 13.8 5.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF2062 PF09835.9 CDJ49077.1 - 0.028 14.3 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CD20 PF04103.15 CDJ49077.1 - 0.038 14.1 4.9 0.091 12.8 0.0 2.3 2 0 0 2 2 2 0 CD20-like family SART-1 PF03343.13 CDJ49077.1 - 0.13 10.8 26.6 0.17 10.4 26.6 1.1 1 0 0 1 1 1 0 SART-1 family DUF572 PF04502.13 CDJ49077.1 - 0.24 11.0 22.1 0.32 10.6 22.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.9 CDJ49077.1 - 0.27 10.1 22.3 0.35 9.7 22.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain rRNA_processing PF08524.11 CDJ49077.1 - 0.29 11.1 31.9 0.65 10.0 12.7 2.1 2 0 0 2 2 2 0 rRNA processing Rrp15p PF07890.12 CDJ49077.1 - 0.34 11.2 23.6 1.8 8.9 6.7 2.3 2 0 0 2 2 2 0 Rrp15p ATAD4 PF15321.6 CDJ49077.1 - 0.35 12.2 17.3 0.4 12.0 1.3 2.3 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Miga PF10265.9 CDJ49077.1 - 0.37 9.7 15.5 0.4 9.6 15.5 1.2 1 0 0 1 1 1 0 Mitoguardin DUF5523 PF17661.1 CDJ49077.1 - 0.38 10.4 25.5 0.56 9.9 25.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Hid1 PF12722.7 CDJ49077.1 - 0.67 8.0 24.4 0.77 7.8 24.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PcfK PF14058.6 CDJ49077.1 - 0.71 10.1 19.4 0.048 13.9 2.4 2.2 2 0 0 2 2 2 0 PcfK-like protein RAB3GAP2_N PF14655.6 CDJ49077.1 - 0.93 8.7 17.3 0.77 8.9 2.3 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus EFTUD2 PF16004.5 CDJ49077.1 - 0.96 10.0 26.5 3.5 8.2 11.1 2.1 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF2722 PF10846.8 CDJ49077.1 - 0.99 8.3 61.1 1.9 7.3 24.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) CBP4 PF07960.11 CDJ49077.1 - 1.1 9.2 20.6 1 9.2 4.9 2.2 2 0 0 2 2 2 0 CBP4 XRN_M PF17846.1 CDJ49077.1 - 1.1 8.1 14.6 1.4 7.8 14.6 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF533 PF04391.12 CDJ49077.1 - 1.1 8.8 22.0 0.69 9.5 6.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF533) PI3K_1B_p101 PF10486.9 CDJ49077.1 - 1.4 6.6 20.0 1.8 6.2 20.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SLC12 PF03522.15 CDJ49077.1 - 1.5 7.8 26.7 1.9 7.4 26.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SR-25 PF10500.9 CDJ49077.1 - 1.8 8.1 38.3 7.2 6.1 38.3 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 CDJ49077.1 - 2.3 5.2 23.2 2.5 5.1 23.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer WDCP PF15390.6 CDJ49077.1 - 2.7 6.3 20.2 3.2 6.0 20.2 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Spore_III_AF PF09581.10 CDJ49077.1 - 2.9 7.9 16.4 1.2 9.1 2.6 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Coilin_N PF15862.5 CDJ49077.1 - 3.5 7.4 36.6 2 8.2 16.4 2.1 2 0 0 2 2 2 0 Coilin N-terminus Peroxin-3 PF04882.12 CDJ49077.1 - 3.5 6.5 29.1 4.7 6.1 29.1 1.1 1 0 0 1 1 1 0 Peroxin-3 UPF0239 PF06783.11 CDJ49077.1 - 3.8 7.8 15.1 5.1 7.3 4.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) DUF3405 PF11885.8 CDJ49077.1 - 4.4 5.8 17.4 0.7 8.4 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3405) LAP1C PF05609.12 CDJ49077.1 - 5.1 6.1 28.8 6.1 5.8 28.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) tRNA_synt_1c_R2 PF04557.15 CDJ49077.1 - 5.5 8.0 18.3 4.6 8.2 5.0 2.5 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Jak1_Phl PF17887.1 CDJ49077.1 - 5.5 6.9 19.6 3.9 7.4 4.6 2.2 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain U3_snoRNA_assoc PF08297.11 CDJ49077.1 - 5.9 7.7 17.3 10 6.9 4.1 2.2 2 0 0 2 2 2 0 U3 snoRNA associated DUF2227 PF09988.9 CDJ49077.1 - 6.3 6.6 5.6 2.1 8.2 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) MAT1 PF06391.13 CDJ49077.1 - 8 6.2 33.0 13 5.6 33.0 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF2681 PF10883.8 CDJ49077.1 - 8.3 6.9 43.5 0.56 10.6 20.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) AXIN1_TNKS_BD PF16646.5 CDJ49077.1 - 9 7.3 14.9 2.6 9.0 1.4 2.5 2 0 0 2 2 2 0 Axin-1 tankyrase binding domain SID-1_RNA_chan PF13965.6 CDJ49078.1 - 0.22 9.9 0.8 0.27 9.6 0.8 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CPSF100_C PF13299.6 CDJ49078.1 - 0.27 11.4 21.0 0.069 13.3 8.1 3.2 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 CDJ49078.1 - 0.77 9.5 19.4 0.19 11.5 7.8 3.0 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.7 CDJ49078.1 - 1.3 9.3 27.5 0.15 12.3 13.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) MMU163 PF17119.5 CDJ49078.1 - 8.5 5.4 15.4 0.018 14.2 3.6 2.3 3 0 0 3 3 3 0 Mitochondrial protein up-regulated during meiosis Caldesmon PF02029.15 CDJ49080.1 - 0.0041 15.9 27.5 0.013 14.3 27.5 1.7 1 1 0 1 1 1 1 Caldesmon PUA_3 PF17785.1 CDJ49081.1 - 4.3e-06 26.4 0.0 1.8e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 PUA-like domain DUF3446 PF11928.8 CDJ49081.1 - 0.092 13.1 41.1 0.32 11.3 9.1 3.5 3 0 0 3 3 3 0 Early growth response N-terminal domain IMUP PF15761.5 CDJ49081.1 - 0.19 12.5 42.0 2.1 9.1 9.5 3.6 3 0 0 3 3 3 0 Immortalisation up-regulated protein Apt1 PF10351.9 CDJ49081.1 - 0.66 8.8 13.8 0.7 8.7 1.3 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF3558 PF12079.8 CDJ49081.1 - 1 9.4 19.7 3.8 7.5 3.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3558) Secretin_N_2 PF07655.13 CDJ49081.1 - 6.8 7.3 35.4 6.8 7.3 9.2 3.3 3 0 0 3 3 3 0 Secretin N-terminal domain eIF3_subunit PF08597.10 CDJ49082.1 - 0.63 9.9 15.2 0.97 9.3 15.2 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Striatin PF08232.12 CDJ49082.1 - 1.5 9.4 6.2 2.2 8.9 6.2 1.2 1 0 0 1 1 1 0 Striatin family Aminotran_1_2 PF00155.21 CDJ49083.1 - 5.8e-39 134.3 0.0 8.4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 CDJ49083.1 - 9.8e-06 24.5 0.1 4.6e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 CDJ49083.1 - 9e-05 21.2 0.0 0.00016 20.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CDJ49083.1 - 0.018 14.4 0.6 0.047 13.0 0.6 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CDJ49083.1 - 0.031 13.6 0.1 0.055 12.7 0.1 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Cpn60_TCP1 PF00118.24 CDJ49084.1 - 4.9e-82 276.1 0.8 1.6e-81 274.4 0.8 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family GP3_package PF16677.5 CDJ49084.1 - 0.13 12.4 1.0 3.3 7.9 0.1 2.5 2 0 0 2 2 2 0 DNA-packaging protein gp3 DNA_primase_lrg PF04104.14 CDJ49084.1 - 0.47 9.8 3.1 1.5 8.1 0.3 2.1 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Beta-Casp PF10996.8 CDJ49085.1 - 9.6e-23 80.6 0.0 2e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 CDJ49085.1 - 2.5e-15 56.1 0.0 4.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 CDJ49085.1 - 3.1e-08 33.3 0.0 1.5e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ49085.1 - 7.1e-06 26.2 0.0 0.0001 22.4 0.0 2.8 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ49085.1 - 0.0051 16.4 2.5 0.086 12.3 0.0 3.0 4 0 0 4 4 4 1 Beta-lactamase superfamily domain NGP1NT PF08153.12 CDJ49086.1 - 1.5e-35 122.2 0.0 3.2e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CDJ49086.1 - 1.4e-15 57.3 0.0 8.4e-13 48.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ49086.1 - 1.1e-06 28.6 0.0 2.6e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 CDJ49086.1 - 4.6e-05 23.0 0.0 0.0053 16.3 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Arf PF00025.21 CDJ49086.1 - 0.00072 19.1 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ49086.1 - 0.0009 18.8 0.1 0.0086 15.6 0.1 2.2 1 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CDJ49086.1 - 0.11 12.5 0.3 9.1 6.3 0.0 3.0 2 1 1 3 3 3 0 Dynamin family ERGIC_N PF13850.6 CDJ49087.1 - 0.05 13.9 1.1 0.4 11.1 0.4 2.8 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SID-1_RNA_chan PF13965.6 CDJ49089.1 - 0.018 13.5 9.2 0.018 13.5 9.2 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NUMOD3 PF07460.11 CDJ49089.1 - 0.15 12.3 0.1 28 5.0 0.1 2.3 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) PCM1_C PF15717.5 CDJ49090.1 - 0.15 10.8 23.2 0.16 10.6 23.2 1.0 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus SMYLE_N PF18615.1 CDJ49090.1 - 0.82 9.2 16.6 0.92 9.0 16.6 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Pox_RNA_Pol_19 PF05320.12 CDJ49090.1 - 1.3 9.0 10.0 1.5 8.8 9.5 1.3 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PBP1_TM PF14812.6 CDJ49090.1 - 8.3 6.9 13.8 21 5.5 13.8 1.7 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vfa1 PF08432.10 CDJ49090.1 - 9.3 6.5 26.8 11 6.3 26.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Comm PF15957.5 CDJ49091.1 - 1.3 9.4 10.6 1.6 9.1 7.1 2.2 2 0 0 2 2 2 0 Commissureless U1snRNP70_N PF12220.8 CDJ49091.1 - 4.4 8.0 23.5 1.4 9.6 7.9 3.1 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Neur_chan_memb PF02932.16 CDJ49091.1 - 4.6 7.2 19.3 6.5 6.7 19.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp_protease_2 PF13650.6 CDJ49092.1 - 4.8e-08 33.5 0.0 1.1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ49092.1 - 2.3e-07 31.3 0.0 6.3e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ49092.1 - 4.6e-07 29.7 0.0 7.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CDJ49092.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-RVT PF13966.6 CDJ49093.1 - 0.00014 22.5 1.2 0.00026 21.6 0.1 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Cwf_Cwc_15 PF04889.12 CDJ49095.1 - 0.0048 16.7 1.0 0.0056 16.5 1.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein FHIPEP PF00771.20 CDJ49095.1 - 0.036 12.5 0.7 0.043 12.3 0.7 1.1 1 0 0 1 1 1 0 FHIPEP family Lin-8 PF03353.15 CDJ49095.1 - 0.059 12.9 12.3 0.068 12.7 12.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ49095.1 - 0.066 11.8 11.9 0.074 11.6 11.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF1645 PF07816.11 CDJ49095.1 - 0.084 13.5 11.2 0.1 13.2 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) TFIIA PF03153.13 CDJ49095.1 - 0.1 12.5 26.5 0.12 12.3 26.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MPM1 PF17234.2 CDJ49095.1 - 0.17 12.1 8.0 0.27 11.5 8.0 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 OmpH PF03938.14 CDJ49095.1 - 0.23 11.8 18.0 0.4 11.0 18.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PAP1 PF08601.10 CDJ49095.1 - 0.28 10.8 15.9 0.35 10.5 15.9 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Sec16 PF12932.7 CDJ49095.1 - 0.36 11.4 5.2 0.12 12.9 1.1 2.1 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region DUF2849 PF11011.8 CDJ49095.1 - 0.46 11.2 2.3 0.64 10.7 1.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2849) CDK2AP PF09806.9 CDJ49095.1 - 0.58 10.2 15.2 0.33 11.0 13.5 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Peptidase_S64 PF08192.11 CDJ49095.1 - 0.73 8.3 12.0 0.77 8.2 12.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Roughex PF06020.11 CDJ49095.1 - 0.97 8.5 6.0 1.2 8.1 6.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Pheromone PF08015.11 CDJ49095.1 - 1.5 9.9 10.8 4.2 8.5 10.8 1.7 1 0 0 1 1 1 0 Fungal mating-type pheromone CSG2 PF16965.5 CDJ49095.1 - 2 7.3 10.7 0.22 10.4 6.6 1.4 2 0 0 2 2 2 0 Ceramide synthase regulator DUF1180 PF06679.12 CDJ49095.1 - 2.7 8.4 15.8 0.24 11.8 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) PAT1 PF09770.9 CDJ49095.1 - 2.7 6.1 18.6 3.3 5.9 18.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ49095.1 - 2.9 4.9 16.9 3.4 4.7 16.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Miga PF10265.9 CDJ49095.1 - 6 5.7 11.9 6.5 5.6 11.9 1.1 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 CDJ49096.1 - 0.0021 16.7 10.5 0.0021 16.7 10.5 4.0 4 1 0 4 4 4 1 Macoilin family Spt20 PF12090.8 CDJ49096.1 - 0.0047 16.6 11.2 0.0047 16.6 11.2 6.1 5 1 0 5 5 5 1 Spt20 family SR-25 PF10500.9 CDJ49096.1 - 0.0049 16.5 8.6 0.0049 16.5 8.6 5.2 4 1 1 5 5 5 3 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ49096.1 - 0.031 14.5 0.6 0.031 14.5 0.6 5.4 4 1 1 5 5 5 0 Centriole, cilia and spindle-associated Peptidase_S64 PF08192.11 CDJ49096.1 - 1.2 7.5 35.1 0.66 8.4 1.7 3.2 3 0 0 3 3 3 0 Peptidase family S64 Ham1p_like PF01725.16 CDJ49097.1 - 9.6e-37 126.7 0.0 7.6e-18 65.1 0.0 2.4 1 1 1 2 2 2 2 Ham1 family TRAPPC9-Trs120 PF08626.11 CDJ49097.1 - 0.12 9.7 0.0 0.14 9.5 0.0 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF508 PF04370.12 CDJ49097.1 - 1.5 8.6 8.7 2.6 7.8 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) SR-25 PF10500.9 CDJ49097.1 - 2 8.0 21.1 0.064 12.9 15.2 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein UBA PF00627.31 CDJ49099.1 - 4e-05 23.4 0.2 8.4e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain FAM199X PF15814.5 CDJ49099.1 - 0.038 13.1 6.4 1.3 8.0 6.9 2.0 1 1 1 2 2 2 0 Protein family FAM199X Hamartin PF04388.12 CDJ49099.1 - 0.075 11.7 3.6 0.08 11.6 3.6 1.1 1 0 0 1 1 1 0 Hamartin protein Syntaxin-18_N PF10496.9 CDJ49099.1 - 0.14 12.4 0.1 10 6.4 0.0 2.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Ndc1_Nup PF09531.10 CDJ49099.1 - 0.74 8.4 6.7 0.89 8.2 6.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LIM_bind PF01803.16 CDJ49099.1 - 1.1 8.7 4.4 1.9 8.0 4.4 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Med15 PF09606.10 CDJ49099.1 - 2.9 6.5 22.4 3.6 6.2 22.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.9 CDJ49099.1 - 4.6 5.4 15.5 5.8 5.0 15.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOG2 PF10428.9 CDJ49099.1 - 5.3 6.1 11.3 7 5.7 11.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Suf PF05843.14 CDJ49099.1 - 9.2 6.2 8.9 13 5.7 8.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LUC7 PF03194.15 CDJ49100.1 - 8.6e-49 166.5 0.0 8.6e-49 166.5 0.0 2.4 1 1 1 2 2 2 1 LUC7 N_terminus Draxin PF15550.6 CDJ49100.1 - 0.0093 15.9 7.7 0.016 15.1 7.7 1.4 1 0 0 1 1 1 1 Draxin DUF4080 PF13311.6 CDJ49100.1 - 0.073 13.3 4.3 0.17 12.1 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) DUF4666 PF15697.5 CDJ49100.1 - 0.13 13.0 5.6 0.37 11.5 5.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) Protocadherin PF08374.11 CDJ49100.1 - 0.37 10.8 4.4 0.68 9.9 4.4 1.4 1 0 0 1 1 1 0 Protocadherin Peroxin-13_N PF04088.13 CDJ49100.1 - 0.72 10.1 4.2 1.6 9.0 4.2 1.7 1 0 0 1 1 1 0 Peroxin 13, N-terminal region BPL_N PF09825.9 CDJ49100.1 - 0.83 8.7 6.1 1.4 8.0 6.1 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal ALMT PF11744.8 CDJ49100.1 - 2.7 6.7 5.7 4.1 6.1 5.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CPSF100_C PF13299.6 CDJ49100.1 - 3.6 7.7 14.8 0.41 10.8 9.7 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.19 CDJ49100.1 - 6.2 4.6 9.2 8.6 4.1 9.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spt20 PF12090.8 CDJ49102.1 - 0.0008 19.1 17.9 0.0008 19.1 17.9 1.2 1 0 0 1 1 1 1 Spt20 family DUF3276 PF11680.8 CDJ49102.1 - 0.00099 19.3 4.3 0.0011 19.2 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3276) REPA_OB_2 PF16900.5 CDJ49102.1 - 0.0033 17.3 0.4 0.005 16.7 0.3 1.4 1 1 0 1 1 1 1 Replication protein A OB domain CobT PF06213.12 CDJ49102.1 - 0.005 16.3 6.3 0.005 16.3 6.3 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT DUF4820 PF16091.5 CDJ49102.1 - 0.0054 16.1 3.0 0.0054 16.1 3.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) DUF4834 PF16118.5 CDJ49102.1 - 0.0058 17.6 4.4 0.0059 17.5 4.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ49102.1 - 0.012 15.3 1.4 0.012 15.3 1.4 1.1 1 0 0 1 1 1 0 FAM176 family DcuA_DcuB PF03605.14 CDJ49102.1 - 0.021 13.7 0.8 0.022 13.7 0.8 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Connexin PF00029.19 CDJ49102.1 - 0.022 14.5 3.1 0.022 14.5 3.1 1.0 1 0 0 1 1 1 0 Connexin DUF4770 PF15994.5 CDJ49102.1 - 0.029 14.6 5.7 0.033 14.4 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) HA2 PF04408.23 CDJ49102.1 - 0.039 14.2 1.6 0.043 14.1 1.6 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) G0-G1_switch_2 PF15103.6 CDJ49102.1 - 0.047 14.1 2.9 0.057 13.8 2.9 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 TFIIA PF03153.13 CDJ49102.1 - 0.14 12.2 17.9 0.12 12.3 17.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 CDJ49102.1 - 0.18 11.9 9.0 0.16 12.0 9.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 CDJ49102.1 - 0.2 10.4 5.7 0.19 10.4 5.7 1.1 1 0 0 1 1 1 0 Presenilin Nitroreductase PF00881.24 CDJ49102.1 - 0.21 11.7 3.3 0.23 11.5 3.3 1.0 1 0 0 1 1 1 0 Nitroreductase family DUF4199 PF13858.6 CDJ49102.1 - 0.21 12.0 0.8 0.24 11.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Dpy19 PF10034.9 CDJ49102.1 - 0.23 9.6 2.6 0.24 9.5 2.6 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Rpp20 PF12328.8 CDJ49102.1 - 0.23 11.4 9.1 0.29 11.1 9.1 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Suf PF05843.14 CDJ49102.1 - 0.27 11.2 8.1 0.24 11.3 8.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.10 CDJ49102.1 - 0.31 9.7 18.2 0.28 9.8 18.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AIF_C PF14721.6 CDJ49102.1 - 0.33 11.3 5.0 0.35 11.2 5.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Folate_carrier PF01770.18 CDJ49102.1 - 0.38 9.4 2.6 0.4 9.4 2.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier Orf78 PF06024.12 CDJ49102.1 - 0.41 11.0 2.9 0.51 10.7 2.9 1.2 1 0 0 1 1 1 0 Orf78 (ac78) CLN3 PF02487.17 CDJ49102.1 - 0.45 9.5 3.0 0.44 9.5 3.0 1.0 1 0 0 1 1 1 0 CLN3 protein DUF3464 PF11947.8 CDJ49102.1 - 0.49 10.1 5.9 0.54 10.0 5.9 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 EIIBC-GUT_N PF03612.14 CDJ49102.1 - 0.52 10.0 6.7 0.55 9.9 6.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus EPL1 PF10513.9 CDJ49102.1 - 0.59 10.5 11.7 0.72 10.2 11.7 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Activator_LAG-3 PF11498.8 CDJ49102.1 - 0.68 8.8 26.8 0.7 8.8 26.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CSG2 PF16965.5 CDJ49102.1 - 1 8.2 4.1 1.1 8.1 4.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator UPF0560 PF10577.9 CDJ49102.1 - 1.3 7.4 11.8 1.2 7.5 11.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Androgen_recep PF02166.16 CDJ49102.1 - 3.9 6.2 18.3 3.8 6.2 18.3 1.1 1 0 0 1 1 1 0 Androgen receptor TMEM51 PF15345.6 CDJ49102.1 - 6.5 6.5 11.3 6.9 6.4 11.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 AAA_lid_3 PF17862.1 CDJ49103.1 - 2.1e-09 37.0 0.2 7e-09 35.4 0.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDJ49103.1 - 4.7e-05 23.8 0.0 4.7e-05 23.8 0.0 3.0 2 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SLX9 PF15341.6 CDJ49103.1 - 0.012 16.0 17.4 0.32 11.4 0.2 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Sin_N PF04801.13 CDJ49103.1 - 0.05 12.8 31.0 0.068 12.4 31.0 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF913 PF06025.12 CDJ49103.1 - 0.35 9.8 11.7 0.2 10.6 5.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 CDJ49103.1 - 1.3 7.8 11.2 1.6 7.4 11.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDRGK PF09756.9 CDJ49103.1 - 5.1 6.6 28.7 0.12 11.9 16.5 2.1 2 0 0 2 2 2 0 DDRGK domain Lin-8 PF03353.15 CDJ49103.1 - 8.9 5.8 25.9 3.8 7.0 14.5 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist EURL PF06937.11 CDJ49104.1 - 0.061 12.7 0.2 0.064 12.7 0.2 1.1 1 0 0 1 1 1 0 EURL protein SR-25 PF10500.9 CDJ49104.1 - 0.41 10.2 8.7 0.5 9.9 8.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ49104.1 - 7.6 6.8 13.9 0.13 12.6 6.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) PPL5 PF18168.1 CDJ49106.1 - 4.5e-05 22.9 6.0 4.5e-05 22.9 6.0 7.3 7 1 0 7 7 7 2 Prim-pol family 5 SARAF PF06682.12 CDJ49106.1 - 0.0002 21.2 0.1 0.0002 21.2 0.1 9.0 6 2 0 6 6 6 4 SOCE-associated regulatory factor of calcium homoeostasis Spt20 PF12090.8 CDJ49106.1 - 0.0048 16.5 23.3 0.0048 16.5 23.3 14.6 11 4 2 13 13 13 5 Spt20 family PAP1 PF08601.10 CDJ49106.1 - 0.29 10.8 0.0 0.29 10.8 0.0 10.4 9 3 1 10 10 10 0 Transcription factor PAP1 SUIM_assoc PF16619.5 CDJ49107.1 - 0.075 13.1 6.9 0.079 13.0 0.2 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Dimer_Tnp_hAT PF05699.14 CDJ49107.1 - 0.17 11.7 1.4 3.3 7.6 0.2 2.8 3 0 0 3 3 3 0 hAT family C-terminal dimerisation region PMI_typeI PF01238.21 CDJ49108.1 - 3e-23 82.6 18.9 6.7e-23 81.5 8.7 5.1 3 2 2 5 5 5 2 Phosphomannose isomerase type I RskA PF10099.9 CDJ49108.1 - 4.3e-06 27.1 70.2 0.0067 16.7 12.2 4.5 3 1 0 3 3 3 3 Anti-sigma-K factor rskA SARAF PF06682.12 CDJ49108.1 - 0.0072 16.0 20.3 0.0072 16.0 20.3 4.6 3 1 0 3 3 3 1 SOCE-associated regulatory factor of calcium homoeostasis Peptidase_S49_N PF08496.10 CDJ49108.1 - 0.16 12.0 0.2 0.16 12.0 0.2 5.4 5 1 1 6 6 6 0 Peptidase family S49 N-terminal Cupin_3 PF05899.12 CDJ49108.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.7 CDJ49108.1 - 0.28 10.9 6.8 0.43 10.3 0.0 3.4 3 1 0 3 3 3 0 Cupin TerC PF03741.16 CDJ49108.1 - 0.68 9.6 3.2 9.6 5.8 0.0 3.3 2 1 1 3 3 3 0 Integral membrane protein TerC family Trp_oprn_chp PF09534.10 CDJ49108.1 - 0.88 9.3 33.9 0.94 9.2 1.5 4.0 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CD20 PF04103.15 CDJ49108.1 - 1.2 9.2 0.0 1.2 9.2 0.0 4.7 6 0 0 6 6 6 0 CD20-like family Gaa1 PF04114.14 CDJ49108.1 - 4.8 6.1 24.0 0.21 10.6 0.6 3.5 3 1 0 3 3 3 0 Gaa1-like, GPI transamidase component RQC PF09382.10 CDJ49109.1 - 3.9e-06 26.6 0.0 7.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RQC domain Glt_symporter PF03616.14 CDJ49109.1 - 0.063 12.0 1.3 0.1 11.2 1.3 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter RNA_pol_Rbc25 PF08292.12 CDJ49109.1 - 0.29 11.4 2.9 0.55 10.5 2.9 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 TERB2 PF15101.6 CDJ49109.1 - 0.3 11.1 8.9 0.61 10.1 8.9 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EIIBC-GUT_N PF03612.14 CDJ49109.1 - 0.9 9.3 3.9 2.5 7.8 3.9 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4834 PF16118.5 CDJ49109.1 - 0.96 10.4 8.4 2.5 9.1 8.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 CDJ49109.1 - 2.2 8.3 4.3 0.52 10.3 0.5 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 CDJ49109.1 - 2.6 6.9 9.5 4.8 6.1 9.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Activator_LAG-3 PF11498.8 CDJ49109.1 - 2.6 6.9 32.4 0.24 10.3 23.9 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PRC2_HTH_1 PF18118.1 CDJ49109.1 - 2.7 8.8 5.6 8.3 7.3 5.6 1.7 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain CRF1 PF10380.9 CDJ49109.1 - 2.8 8.3 4.6 3.2 8.1 2.2 2.1 2 0 0 2 2 2 0 Transcription factor CRF1 Presenilin PF01080.17 CDJ49109.1 - 4.2 6.0 9.1 0.064 12.0 1.1 1.9 2 0 0 2 2 2 0 Presenilin PAM2 PF07145.15 CDJ49110.1 - 0.098 12.4 0.1 0.34 10.7 0.1 2.0 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Ost5 PF05251.12 CDJ49111.1 - 0.25 11.6 1.6 0.8 10.0 0.9 2.1 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 PPDFL PF15060.6 CDJ49112.1 - 0.031 14.8 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 Differentiation and proliferation regulator Nucleoside_tran PF01733.18 CDJ49112.1 - 0.15 11.4 2.8 1.5 8.2 0.3 2.2 2 0 0 2 2 2 0 Nucleoside transporter Pkinase PF00069.25 CDJ49113.1 - 1.2e-61 208.4 0.0 1.4e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ49113.1 - 4e-38 131.2 0.0 4.8e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ49113.1 - 2.3e-06 27.7 0.0 0.006 16.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ49113.1 - 0.00011 21.6 0.0 0.00049 19.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDJ49113.1 - 0.00024 20.0 0.0 0.00036 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDJ49113.1 - 0.0021 17.5 0.1 0.0031 16.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S8e PF01201.22 CDJ49114.1 - 2.1e-49 167.2 7.6 3.4e-49 166.5 7.6 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e CCDC-167 PF15188.6 CDJ49114.1 - 0.51 10.7 9.0 2.7 8.4 5.3 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Cyclin_N PF00134.23 CDJ49115.1 - 8e-12 45.0 0.1 8e-12 45.0 0.1 2.4 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ49115.1 - 0.00033 20.7 0.0 0.0062 16.6 0.0 2.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Roughex PF06020.11 CDJ49119.1 - 0.58 9.2 11.4 0.56 9.3 11.4 1.0 1 0 0 1 1 1 0 Drosophila roughex protein DUF2722 PF10846.8 CDJ49119.1 - 1.2 8.0 18.1 1.2 8.0 18.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BRF1 PF07741.13 CDJ49119.1 - 1.3 9.4 8.7 1.3 9.4 8.7 1.0 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF3682 PF12446.8 CDJ49119.1 - 1.5 9.3 17.2 1.7 9.1 17.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Spt20 PF12090.8 CDJ49119.1 - 3.1 7.3 19.5 3.2 7.3 19.5 1.0 1 0 0 1 1 1 0 Spt20 family DUF5349 PF17298.2 CDJ49119.1 - 3.6 7.3 11.6 3.9 7.1 11.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF4834 PF16118.5 CDJ49119.1 - 3.9 8.5 10.8 4 8.5 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 CDJ49119.1 - 7.7 5.2 17.8 7.9 5.2 17.8 1.0 1 0 0 1 1 1 0 Androgen receptor CLAMP PF14769.6 CDJ49121.1 - 9.8e-13 48.4 0.3 1.9e-12 47.4 0.3 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Adaptin_binding PF10199.9 CDJ49121.1 - 0.19 12.4 11.7 0.12 13.0 7.2 2.6 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SUIM_assoc PF16619.5 CDJ49121.1 - 0.21 11.7 30.7 2.5 8.2 6.1 4.6 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SARAF PF06682.12 CDJ49121.1 - 0.41 10.3 21.3 44 3.6 23.2 2.3 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Plasmodium_Vir PF05795.11 CDJ49121.1 - 6.7 6.0 9.8 3.1 7.1 6.4 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Wzz PF02706.15 CDJ49121.1 - 7 7.0 9.6 4.9 7.5 5.6 2.7 2 0 0 2 2 2 0 Chain length determinant protein SUIM_assoc PF16619.5 CDJ49122.1 - 0.015 15.4 5.7 0.015 15.4 5.7 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ49122.1 - 0.11 12.0 21.4 0.081 12.5 7.1 2.1 2 0 0 2 2 2 0 Spt20 family FAM60A PF15396.6 CDJ49122.1 - 0.14 12.2 2.9 0.22 11.5 2.9 1.4 1 1 0 1 1 1 0 Protein Family FAM60A TMEM208_SND2 PF05620.11 CDJ49122.1 - 0.38 10.5 3.5 0.87 9.3 1.3 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Activator_LAG-3 PF11498.8 CDJ49122.1 - 1.1 8.2 27.3 0.086 11.8 8.8 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Nuc_deoxyrib_tr PF05014.15 CDJ49122.1 - 1.6 8.7 7.7 0.51 10.4 3.2 2.0 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase SOG2 PF10428.9 CDJ49123.1 - 1.8 7.7 25.8 2.4 7.2 25.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.13 CDJ49123.1 - 2.1 7.9 21.7 2.4 7.7 21.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) PPP4R2 PF09184.11 CDJ49123.1 - 7.6 6.0 15.6 9.5 5.7 15.6 1.1 1 0 0 1 1 1 0 PPP4R2 SPX PF03105.19 CDJ49124.1 - 0.00018 21.6 9.2 0.00022 21.3 9.2 1.1 1 0 0 1 1 1 1 SPX domain Efg1 PF10153.9 CDJ49124.1 - 0.082 13.3 12.8 0.14 12.5 12.8 1.3 1 0 0 1 1 1 0 rRNA-processing protein Efg1 RAP1 PF07218.11 CDJ49124.1 - 0.14 10.4 7.2 0.17 10.1 7.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF45 PF01863.17 CDJ49124.1 - 0.38 10.8 8.8 0.59 10.1 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 Secretin_N_2 PF07655.13 CDJ49124.1 - 2.8 8.6 20.7 0.66 10.6 16.1 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain CLN3 PF02487.17 CDJ49124.1 - 4.4 6.2 7.0 14 4.6 0.0 2.1 2 0 0 2 2 2 0 CLN3 protein Presenilin PF01080.17 CDJ49124.1 - 5 5.8 13.5 14 4.3 9.1 2.0 2 0 0 2 2 2 0 Presenilin Pex14_N PF04695.13 CDJ49125.1 - 0.0015 19.2 12.9 0.0015 19.2 12.9 21.0 9 4 8 18 18 18 2 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RING_2 PF13639.6 CDJ49125.1 - 0.013 15.8 1.5 0.044 14.1 1.5 1.9 1 0 0 1 1 1 0 Ring finger domain NAM-associated PF14303.6 CDJ49125.1 - 0.32 11.7 0.0 0.32 11.7 0.0 15.8 10 3 6 17 17 17 0 No apical meristem-associated C-terminal domain Macoilin PF09726.9 CDJ49126.1 - 0.0013 17.4 24.1 0.0013 17.4 24.1 6.4 5 2 0 5 5 5 1 Macoilin family RskA PF10099.9 CDJ49126.1 - 0.0017 18.7 10.3 0.0017 18.7 10.3 12.5 5 3 4 10 10 10 3 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ49126.1 - 0.0033 16.5 15.6 0.0033 16.5 15.6 8.3 8 1 0 8 8 8 3 Protein of unknown function (DUF2722) NifU PF01106.17 CDJ49127.1 - 1.7e-31 108.2 3.2 2.5e-18 66.0 0.1 3.4 2 1 1 3 3 3 3 NifU-like domain Cytomega_UL84 PF06284.11 CDJ49127.1 - 9.6 4.5 9.9 17 3.7 9.9 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein MIF4G PF02854.19 CDJ49129.1 - 3.6e-15 56.2 0.4 1.8e-14 53.9 0.4 1.9 1 1 0 1 1 1 1 MIF4G domain Sporozoite_P67 PF05642.11 CDJ49129.1 - 0.3 9.1 13.8 0.44 8.6 13.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIA PF03153.13 CDJ49130.1 - 0.00069 19.7 31.2 0.00078 19.5 31.2 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PmbA_TldD PF01523.16 CDJ49130.1 - 0.0035 17.2 1.7 0.0045 16.9 1.7 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase GET2 PF08690.10 CDJ49130.1 - 0.0056 16.4 12.3 0.0065 16.2 12.3 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 Velvet PF11754.8 CDJ49130.1 - 0.014 15.3 6.0 0.015 15.3 6.0 1.1 1 0 0 1 1 1 0 Velvet factor SprA-related PF12118.8 CDJ49130.1 - 0.038 13.1 29.1 0.043 13.0 29.1 1.1 1 0 0 1 1 1 0 SprA-related family Neur_chan_memb PF02932.16 CDJ49130.1 - 0.046 13.8 4.8 0.046 13.8 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.13 CDJ49130.1 - 0.16 12.6 21.3 0.21 12.2 21.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ49130.1 - 0.17 11.5 33.9 0.24 11.0 33.9 1.3 1 0 0 1 1 1 0 Spt20 family SID-1_RNA_chan PF13965.6 CDJ49130.1 - 0.18 10.2 1.1 0.16 10.3 1.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AMP-binding PF00501.28 CDJ49130.1 - 0.25 9.9 5.5 0.3 9.6 5.5 1.0 1 0 0 1 1 1 0 AMP-binding enzyme API5 PF05918.11 CDJ49130.1 - 0.31 9.8 18.8 0.35 9.6 18.8 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PA26 PF04636.13 CDJ49130.1 - 0.34 9.8 10.1 0.39 9.6 10.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DDHD PF02862.17 CDJ49130.1 - 0.42 10.7 10.5 0.48 10.6 10.5 1.2 1 0 0 1 1 1 0 DDHD domain LMBR1 PF04791.16 CDJ49130.1 - 0.52 9.2 6.5 0.57 9.0 6.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Dynamin_N PF00350.23 CDJ49130.1 - 0.68 10.0 6.6 0.91 9.6 6.6 1.2 1 0 0 1 1 1 0 Dynamin family DUF3381 PF11861.8 CDJ49130.1 - 0.68 9.7 19.6 1 9.1 19.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Cellulose_synt PF03552.14 CDJ49130.1 - 0.77 8.2 4.9 0.92 7.9 4.9 1.0 1 0 0 1 1 1 0 Cellulose synthase GBP_C PF02841.14 CDJ49130.1 - 0.85 9.0 28.3 1 8.7 28.3 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain eIF-3_zeta PF05091.12 CDJ49130.1 - 0.87 8.5 19.5 1.1 8.2 19.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF5568 PF17724.1 CDJ49130.1 - 1.2 9.0 11.0 1.7 8.4 11.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5568) DUF3584 PF12128.8 CDJ49130.1 - 1.4 6.3 27.2 1.5 6.3 27.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 CDJ49130.1 - 1.6 8.2 20.1 2 7.9 20.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Membralin PF09746.9 CDJ49130.1 - 1.7 7.6 7.0 1.9 7.4 7.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein GREB1 PF15782.5 CDJ49130.1 - 1.7 5.6 14.4 1.9 5.5 14.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer YABBY PF04690.13 CDJ49130.1 - 1.9 9.0 11.5 2.6 8.6 11.5 1.2 1 0 0 1 1 1 0 YABBY protein PAT1 PF09770.9 CDJ49130.1 - 2.1 6.5 27.3 2.5 6.3 27.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MCU PF04678.13 CDJ49130.1 - 2.1 8.4 11.3 2.7 8.1 11.3 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF3450 PF11932.8 CDJ49130.1 - 2.3 7.5 34.9 3.4 6.9 34.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RPN2_C PF18004.1 CDJ49130.1 - 2.6 8.0 16.1 3.2 7.6 16.1 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Hydin_ADK PF17213.3 CDJ49130.1 - 3.1 8.0 16.9 3.7 7.8 16.9 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Serinc PF03348.15 CDJ49130.1 - 3.1 6.6 6.8 3.5 6.4 6.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hid1 PF12722.7 CDJ49130.1 - 3.1 5.8 13.6 3.4 5.7 13.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4228 PF14009.6 CDJ49130.1 - 3.2 8.1 14.5 4.7 7.6 14.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) SLC12 PF03522.15 CDJ49130.1 - 3.3 6.6 15.9 3.8 6.4 15.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Activator_LAG-3 PF11498.8 CDJ49130.1 - 3.5 6.5 45.8 4.5 6.1 45.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SpoIIP PF07454.11 CDJ49130.1 - 4.1 6.8 14.3 5 6.5 14.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TERB2 PF15101.6 CDJ49130.1 - 4.6 7.2 18.7 5.7 6.9 18.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 IHABP4_N PF16174.5 CDJ49130.1 - 5 7.7 29.2 6.3 7.4 29.2 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Sec62 PF03839.16 CDJ49130.1 - 5.3 6.5 14.4 6.5 6.2 14.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 V_ATPase_I PF01496.19 CDJ49130.1 - 5.7 4.7 14.7 6 4.7 14.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paramyxo_ncap PF00973.19 CDJ49130.1 - 7.2 5.4 12.9 8.9 5.1 12.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF913 PF06025.12 CDJ49130.1 - 8.3 5.3 10.9 10 5.0 10.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Band_3_cyto PF07565.13 CDJ49130.1 - 9.1 6.0 14.4 12 5.6 14.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BAF1_ABF1 PF04684.13 CDJ49130.1 - 9.8 5.1 21.9 13 4.7 21.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Integrase_H2C2 PF17921.1 CDJ49131.1 - 5.4e-20 71.3 1.2 3.2e-19 68.8 1.0 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CDJ49131.1 - 5.2e-17 61.7 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 CDJ49131.1 - 1.4e-06 28.1 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 CDJ49131.1 - 3.2e-06 27.4 0.0 7.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CDJ49131.1 - 0.00019 21.6 0.0 0.00062 19.9 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger Herpes_UL47 PF03362.13 CDJ49131.1 - 0.017 13.9 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL47 protein DUF3828 PF12883.7 CDJ49131.1 - 0.031 14.6 0.0 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) PAP2 PF01569.21 CDJ49132.1 - 0.25 11.1 1.6 7.5 6.3 0.0 2.2 2 0 0 2 2 2 0 PAP2 superfamily RRP36 PF06102.12 CDJ49132.1 - 4.4 7.3 40.4 0.07 13.1 19.5 2.2 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 SR-25 PF10500.9 CDJ49132.1 - 5.7 6.5 57.9 5.4 6.6 13.5 3.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein UBA_e1_thiolCys PF10585.9 CDJ49133.1 - 3e-28 99.4 6.9 7.4e-28 98.1 1.4 2.1 1 1 1 2 2 2 1 Ubiquitin-activating enzyme active site DDHD PF02862.17 CDJ49133.1 - 0.0052 17.0 0.3 0.0052 17.0 0.3 1.1 1 0 0 1 1 1 1 DDHD domain Tim54 PF11711.8 CDJ49133.1 - 0.0095 14.8 0.2 0.0095 14.8 0.2 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF4746 PF15928.5 CDJ49133.1 - 0.014 14.9 1.3 0.015 14.7 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF702 PF05142.12 CDJ49133.1 - 0.017 15.6 1.1 0.022 15.2 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) V_ATPase_I PF01496.19 CDJ49133.1 - 0.023 12.6 5.9 0.026 12.5 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Suf PF05843.14 CDJ49133.1 - 0.024 14.6 5.4 0.029 14.4 5.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PPL5 PF18168.1 CDJ49133.1 - 0.031 13.6 1.0 0.038 13.3 1.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF913 PF06025.12 CDJ49133.1 - 0.032 13.2 1.2 0.033 13.2 1.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFB6 PF17110.5 CDJ49133.1 - 0.032 14.0 4.9 0.045 13.5 4.9 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH FAM91_C PF14648.6 CDJ49133.1 - 0.033 13.0 1.5 0.037 12.9 1.5 1.1 1 0 0 1 1 1 0 FAM91 C-terminus FAM176 PF14851.6 CDJ49133.1 - 0.054 13.2 2.9 0.079 12.6 2.9 1.3 1 0 0 1 1 1 0 FAM176 family EIIBC-GUT_N PF03612.14 CDJ49133.1 - 0.054 13.2 4.5 0.071 12.8 4.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus OATP PF03137.20 CDJ49133.1 - 0.059 11.7 0.3 0.072 11.4 0.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SpoIIP PF07454.11 CDJ49133.1 - 0.062 12.7 6.0 0.071 12.6 6.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) 5_nucleotid PF05761.14 CDJ49133.1 - 0.082 11.8 3.5 0.1 11.5 3.5 1.0 1 0 0 1 1 1 0 5' nucleotidase family Connexin PF00029.19 CDJ49133.1 - 0.084 12.6 0.7 0.097 12.4 0.7 1.2 1 0 0 1 1 1 0 Connexin AIF_C PF14721.6 CDJ49133.1 - 0.088 13.2 3.2 0.13 12.6 3.2 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TERB2 PF15101.6 CDJ49133.1 - 0.098 12.7 6.3 0.11 12.5 6.3 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Plasmodium_Vir PF05795.11 CDJ49133.1 - 0.099 12.0 0.4 0.095 12.1 0.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF719 PF05334.13 CDJ49133.1 - 0.11 12.7 6.6 0.14 12.3 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) DUF3464 PF11947.8 CDJ49133.1 - 0.12 12.1 4.6 0.16 11.7 4.6 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CPSF100_C PF13299.6 CDJ49133.1 - 0.18 12.0 4.4 0.23 11.6 4.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CDJ49133.1 - 0.21 10.3 6.4 0.24 10.1 6.4 1.1 1 0 0 1 1 1 0 Presenilin F-protein PF00469.20 CDJ49133.1 - 0.34 10.5 6.2 0.39 10.3 6.2 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Het-C PF07217.11 CDJ49133.1 - 0.36 9.3 4.3 0.39 9.2 4.3 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF4820 PF16091.5 CDJ49133.1 - 0.48 9.8 6.9 0.63 9.4 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) MscS_TM PF12794.7 CDJ49133.1 - 0.52 9.1 6.5 0.63 8.9 6.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SKA1 PF07160.12 CDJ49133.1 - 0.56 10.0 11.0 0.65 9.8 11.0 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CLN3 PF02487.17 CDJ49133.1 - 0.64 9.0 1.6 0.75 8.8 1.6 1.1 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 CDJ49133.1 - 0.72 9.9 4.7 0.92 9.5 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SseC PF04888.12 CDJ49133.1 - 0.8 9.2 10.6 1 8.9 10.6 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Med15 PF09606.10 CDJ49133.1 - 0.8 8.3 20.3 0.94 8.1 20.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ49133.1 - 0.91 9.1 27.3 1.3 8.6 27.3 1.1 1 0 0 1 1 1 0 Spt20 family CobT PF06213.12 CDJ49133.1 - 0.92 8.8 17.2 1.1 8.6 17.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Folliculin PF11704.8 CDJ49133.1 - 1.1 9.1 4.8 1.4 8.7 4.8 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport PBP1_TM PF14812.6 CDJ49133.1 - 1.1 9.6 6.7 1.8 9.0 6.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4834 PF16118.5 CDJ49133.1 - 1.7 9.6 9.7 2.7 9.0 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ALMT PF11744.8 CDJ49133.1 - 2 7.1 5.2 2.4 6.9 5.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM60A PF15396.6 CDJ49133.1 - 2.2 8.2 5.7 2.8 7.9 5.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A OmpH PF03938.14 CDJ49133.1 - 2.6 8.4 25.8 3.6 7.9 25.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CDJ49133.1 - 3.6 6.9 12.4 4.5 6.5 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ49133.1 - 4.1 7.3 23.6 5.1 7.0 23.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0560 PF10577.9 CDJ49133.1 - 4.2 5.7 15.0 5.1 5.5 15.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF5421 PF17458.2 CDJ49133.1 - 5.5 6.3 15.2 7.6 5.8 15.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) CDC45 PF02724.14 CDJ49133.1 - 6.4 4.9 10.4 7.9 4.6 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein UIM PF02809.20 CDJ49135.1 - 0.0054 16.6 1.8 0.018 14.9 0.8 2.2 2 0 0 2 2 2 1 Ubiquitin interaction motif Ribosomal_L2_C PF03947.18 CDJ49136.1 - 1.2e-43 148.3 2.4 1.2e-43 148.3 2.4 2.0 3 0 0 3 3 3 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CDJ49136.1 - 1.6e-17 63.3 0.1 3.7e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Activator_LAG-3 PF11498.8 CDJ49137.1 - 4.6e-05 22.6 7.1 4.6e-05 22.6 7.1 8.2 7 1 1 8 8 8 1 Transcriptional activator LAG-3 MFS_1 PF07690.16 CDJ49138.1 - 8.7e-12 44.6 30.5 8.7e-12 44.6 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.22 CDJ49138.1 - 9.6e-05 21.7 0.0 9.6e-05 21.7 0.0 2.7 2 1 1 3 3 3 1 ZIP Zinc transporter NSF PF02071.20 CDJ49138.1 - 0.61 11.1 2.0 1.8 9.6 2.0 1.9 1 0 0 1 1 1 0 Aromatic-di-Alanine (AdAR) repeat DUF5504 PF17608.2 CDJ49138.1 - 2.3 8.4 5.4 0.53 10.4 0.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5504) PCI PF01399.27 CDJ49139.1 - 7.9e-15 55.3 0.0 1.9e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain RPN6_N PF18055.1 CDJ49139.1 - 5.9e-13 49.2 0.1 3.1e-12 46.9 0.0 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain RPN6_C_helix PF18503.1 CDJ49139.1 - 0.013 15.2 0.5 0.023 14.4 0.5 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain Antimicrobial24 PF16049.5 CDJ49140.1 - 0.031 14.2 2.5 0.066 13.2 2.5 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide SPX PF03105.19 CDJ49140.1 - 6.7 6.5 30.2 3.3 7.5 0.0 2.1 1 1 1 2 2 2 0 SPX domain RVT_1 PF00078.27 CDJ49142.1 - 3.3e-17 62.7 0.0 5.6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 CDJ49142.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain CRAL_TRIO PF00650.20 CDJ49144.1 - 5e-12 45.8 0.0 8.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2722 PF10846.8 CDJ49144.1 - 0.0099 14.9 0.0 0.0099 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF1180 PF06679.12 CDJ49144.1 - 0.065 13.6 1.9 0.12 12.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CENP-X PF09415.10 CDJ49144.1 - 0.14 12.5 0.2 3.2 8.1 0.0 2.2 2 0 0 2 2 2 0 CENP-S associating Centromere protein X SpoV PF08183.11 CDJ49144.1 - 0.39 10.7 1.6 0.91 9.5 1.6 1.6 1 0 0 1 1 1 0 Stage V sporulation protein family Spt20 PF12090.8 CDJ49144.1 - 5.1 6.6 11.7 8.2 6.0 11.7 1.2 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ49145.1 - 0.0028 17.3 22.1 0.0035 17.0 22.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TFIIF_alpha PF05793.12 CDJ49145.1 - 0.0052 15.4 22.0 0.0057 15.3 22.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CbtB PF09489.10 CDJ49145.1 - 0.066 13.3 2.6 0.16 12.1 2.6 1.7 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) PNISR PF15996.5 CDJ49145.1 - 0.35 11.1 35.9 0.49 10.7 35.9 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SOG2 PF10428.9 CDJ49145.1 - 0.38 9.9 32.7 0.43 9.7 32.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Plasmodium_Vir PF05795.11 CDJ49145.1 - 0.59 9.5 23.6 0.79 9.1 23.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.9 CDJ49145.1 - 2.3 6.7 32.9 2.8 6.4 32.9 1.0 1 0 0 1 1 1 0 Macoilin family Draxin PF15550.6 CDJ49145.1 - 2.3 8.0 26.2 2.7 7.8 26.2 1.0 1 0 0 1 1 1 0 Draxin AF-4 PF05110.13 CDJ49145.1 - 2.6 6.0 38.3 3 5.8 38.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MMR1 PF08505.10 CDJ49145.1 - 4.6 7.5 42.0 5.9 7.1 42.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Spc7_N PF15402.6 CDJ49145.1 - 7.6 4.6 35.4 9.1 4.4 35.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 NCKAP5 PF15246.6 CDJ49145.1 - 8.2 5.9 35.8 9.8 5.7 35.8 1.0 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein PAT1 PF09770.9 CDJ49145.1 - 8.2 4.5 49.7 9.8 4.3 49.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mitofilin PF09731.9 CDJ49145.1 - 8.4 5.1 39.5 10 4.8 39.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Atg14 PF10186.9 CDJ49145.1 - 9.9 5.1 33.9 12 4.9 33.9 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 EzrA PF06160.12 CDJ49146.1 - 0.013 13.7 38.8 0.023 12.9 38.8 1.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Metalloenzyme PF01676.18 CDJ49146.1 - 0.4 10.0 1.4 0.54 9.6 1.4 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily TFIIA PF03153.13 CDJ49146.1 - 1.2 9.1 34.3 1.6 8.7 34.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF_A PF03178.15 CDJ49147.1 - 2.7e-15 56.5 0.0 4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 CPSF A subunit region Spt20 PF12090.8 CDJ49147.1 - 3.7 7.1 8.4 5.4 6.6 8.4 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ49147.1 - 6.3 6.7 11.2 9.1 6.2 11.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ49148.1 - 5.1e-06 26.9 10.4 5.1e-06 26.9 10.4 3.4 1 1 2 3 3 3 1 Anti-sigma-K factor rskA DUF3682 PF12446.8 CDJ49148.1 - 0.0025 18.3 31.2 0.0025 18.3 31.2 4.1 2 1 1 3 3 3 1 Protein of unknown function (DUF3682) BSP_II PF05432.11 CDJ49148.1 - 9.5 5.8 20.6 1.9 8.1 13.1 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) RVT_1 PF00078.27 CDJ49150.1 - 7.7e-08 32.1 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.17 CDJ49151.1 - 0.0005 18.9 10.2 0.00072 18.4 10.2 1.2 1 0 0 1 1 1 1 Presenilin DUF2828 PF11443.8 CDJ49151.1 - 0.0013 16.9 2.3 0.0013 16.9 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) RAP1 PF07218.11 CDJ49151.1 - 0.0014 17.0 3.6 0.0018 16.7 3.6 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Secretin_N_2 PF07655.13 CDJ49151.1 - 0.0019 18.7 5.8 0.0019 18.7 5.8 2.2 2 0 0 2 2 2 1 Secretin N-terminal domain eIF-3_zeta PF05091.12 CDJ49151.1 - 0.0045 16.0 8.4 0.0045 16.0 8.4 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PRIMA1 PF16101.5 CDJ49151.1 - 0.0072 16.4 0.3 0.0072 16.4 0.3 2.0 2 0 0 2 2 1 1 Proline-rich membrane anchor 1 NUDIX PF00293.28 CDJ49151.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain DUF5308 PF17233.2 CDJ49151.1 - 0.071 13.3 8.1 0.25 11.6 4.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5308) CPSF100_C PF13299.6 CDJ49151.1 - 0.13 12.4 7.6 2 8.6 8.2 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Coilin_N PF15862.5 CDJ49151.1 - 0.17 11.7 17.3 2.2 8.1 13.3 2.2 2 0 0 2 2 2 0 Coilin N-terminus DUF4834 PF16118.5 CDJ49151.1 - 0.25 12.3 21.4 0.23 12.5 14.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Serinc PF03348.15 CDJ49151.1 - 0.9 8.4 5.2 1.2 8.0 5.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) PRC2_HTH_1 PF18118.1 CDJ49151.1 - 1.9 9.3 10.8 14 6.5 7.7 2.3 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Kei1 PF08552.11 CDJ49151.1 - 3.7 7.4 8.6 0.91 9.4 3.4 2.0 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Band_3_cyto PF07565.13 CDJ49151.1 - 4.1 7.1 14.3 1.6 8.5 9.6 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain MTP18 PF10558.9 CDJ49151.1 - 6.9 6.6 5.9 11 6.0 5.9 1.3 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Ctr PF04145.15 CDJ49151.1 - 9.4 6.8 11.7 12 6.5 5.8 2.1 2 0 0 2 2 2 0 Ctr copper transporter family LAP1C PF05609.12 CDJ49152.1 - 0.65 9.0 15.3 0.84 8.7 15.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4813 PF16072.5 CDJ49152.1 - 4.3 6.9 29.2 5.5 6.6 29.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Pkinase PF00069.25 CDJ49154.1 - 1.5e-06 27.8 0.0 1.5e-06 27.8 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ49154.1 - 4.2e-06 26.2 0.6 4.2e-06 26.2 0.6 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase TFIIA PF03153.13 CDJ49154.1 - 0.088 12.8 37.8 0.11 12.5 37.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ49154.1 - 0.16 9.8 10.7 0.18 9.7 10.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM222A PF15258.6 CDJ49154.1 - 0.47 9.5 24.6 0.52 9.4 24.6 1.0 1 0 0 1 1 1 0 Protein family of FAM222A ALMT PF11744.8 CDJ49154.1 - 0.56 9.0 8.0 0.77 8.5 8.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CLN3 PF02487.17 CDJ49154.1 - 1.5 7.8 8.0 2 7.4 8.0 1.2 1 0 0 1 1 1 0 CLN3 protein PepSY_TM PF03929.16 CDJ49154.1 - 4 7.0 5.0 5 6.7 5.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region Membralin PF09746.9 CDJ49154.1 - 9.5 5.1 6.8 10 5.0 6.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein Sec7_N PF12783.7 CDJ49155.1 - 3.7e-08 33.4 2.6 3.7e-08 33.4 2.6 3.7 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal RskA PF10099.9 CDJ49155.1 - 3e-05 24.4 14.8 3e-05 24.4 14.8 26.2 5 3 13 20 20 20 5 Anti-sigma-K factor rskA Adaptin_binding PF10199.9 CDJ49155.1 - 4.8 7.8 0.0 4.8 7.8 0.0 13.3 5 5 3 8 8 8 0 Alpha and gamma adaptin binding protein p34 SNF2_N PF00176.23 CDJ49156.1 - 1.1e-51 175.6 0.1 2.6e-51 174.4 0.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ49156.1 - 3.1e-15 56.5 0.3 1.2e-14 54.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD PF00628.29 CDJ49156.1 - 5.6e-13 48.6 78.3 2.1e-09 37.1 9.0 7.2 7 1 0 7 7 7 4 PHD-finger ResIII PF04851.15 CDJ49156.1 - 7e-08 32.7 0.0 1.7e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Apt1 PF10351.9 CDJ49156.1 - 0.0009 18.2 6.1 0.0009 18.2 6.1 3.1 3 1 0 3 3 3 1 Golgi-body localisation protein domain PHD_2 PF13831.6 CDJ49156.1 - 0.0034 16.9 1.5 0.0034 16.9 1.5 6.6 7 0 0 7 7 7 1 PHD-finger AAA_14 PF13173.6 CDJ49156.1 - 0.0056 16.7 0.0 0.018 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF4710 PF15828.5 CDJ49156.1 - 0.16 12.1 4.8 0.07 13.3 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) TPH PF13868.6 CDJ49157.1 - 1e-05 24.2 143.0 1.8e-05 23.4 141.7 2.0 1 1 0 1 1 1 1 Trichohyalin-plectin-homology domain SET PF00856.28 CDJ49158.1 - 1.8e-13 51.3 0.0 1.8e-13 51.3 0.0 3.7 3 2 0 3 3 3 1 SET domain Arm PF00514.23 CDJ49159.1 - 5.5e-09 35.8 6.0 0.056 13.5 0.0 6.0 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 CDJ49159.1 - 1.2e-06 28.6 0.1 1.6e-05 25.0 0.0 2.5 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.6 CDJ49159.1 - 1.3e-05 25.5 0.1 0.018 15.4 0.0 4.0 1 1 2 4 4 4 1 HEAT repeats HEAT PF02985.22 CDJ49159.1 - 0.046 14.0 5.2 31 5.2 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat Tim17 PF02466.19 CDJ49161.1 - 5.9e-23 81.4 7.0 8.8e-23 80.8 7.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UPF0060 PF02694.15 CDJ49161.1 - 0.11 12.8 0.8 0.15 12.3 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family RIF5_SNase_2 PF18189.1 CDJ49163.1 - 0.055 13.3 0.2 0.38 10.5 0.1 2.1 2 0 0 2 2 2 0 TbRIF5 SNase domain 2 DUF3128 PF11326.8 CDJ49163.1 - 0.36 11.2 3.4 0.19 12.1 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) DHO_dh PF01180.21 CDJ49167.1 - 4.3e-99 331.4 0.0 4e-97 325.0 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CDJ49167.1 - 0.049 12.6 0.5 0.17 10.9 0.2 1.9 2 1 0 2 2 2 0 FMN-dependent dehydrogenase UvrD-helicase PF00580.21 CDJ49168.1 - 8.8e-42 143.7 0.0 8.8e-42 143.7 0.0 3.2 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CDJ49168.1 - 7e-21 75.0 0.0 2.9e-18 66.4 0.0 5.5 4 1 0 4 4 4 3 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CDJ49168.1 - 4.1e-19 69.4 0.0 1.6e-18 67.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CDJ49168.1 - 3.2e-10 39.7 0.9 0.00025 20.8 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UPF0697 PF15117.6 CDJ49169.1 - 0.068 13.3 2.6 6.6 6.9 0.1 2.8 1 1 1 2 2 2 0 Uncharacterised protein family UPF0697 PRKCSH PF07915.13 CDJ49170.1 - 2.7e-12 47.5 0.0 3.9e-06 27.8 0.0 3.1 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein YccV-like PF08755.11 CDJ49170.1 - 2.6e-11 43.9 0.0 4.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like PRKCSH_1 PF13015.6 CDJ49170.1 - 0.0033 17.1 0.0 0.8 9.4 0.0 2.4 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein OAD_gamma PF04277.13 CDJ49170.1 - 1.6 9.4 0.0 1.6 9.4 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain UCH PF00443.29 CDJ49172.1 - 2.8e-14 53.2 0.0 7.5e-14 51.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF2052 PF09747.9 CDJ49172.1 - 0.015 15.4 1.7 0.015 15.4 1.7 1.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) UCH_1 PF13423.6 CDJ49172.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase RR_TM4-6 PF06459.12 CDJ49172.1 - 7 6.4 8.4 0.36 10.6 1.9 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ49173.1 - 0.0023 16.3 1.5 0.0035 15.7 1.5 1.3 1 0 0 1 1 1 1 CDC45-like protein Phage_H_T_join PF05521.11 CDJ49173.1 - 0.083 13.4 0.2 0.083 13.4 0.2 2.3 2 0 0 2 2 2 0 Phage head-tail joining protein XAP5 PF04921.14 CDJ49173.1 - 0.61 9.9 8.2 0.074 12.9 3.9 1.6 2 0 0 2 2 2 0 XAP5, circadian clock regulator D123 PF07065.14 CDJ49173.1 - 0.75 8.9 10.8 0.1 11.8 6.4 1.7 2 0 0 2 2 2 0 D123 DUF3292 PF11696.8 CDJ49173.1 - 1.1 7.6 11.8 2.1 6.6 10.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) DUF3464 PF11947.8 CDJ49173.1 - 1.8 8.3 9.7 0.13 12.0 3.5 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF719 PF05334.13 CDJ49173.1 - 2 8.6 9.4 1.4 9.1 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) eIF3_subunit PF08597.10 CDJ49173.1 - 3.3 7.6 19.0 0.31 10.9 13.6 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Spt20 PF12090.8 CDJ49173.1 - 3.3 7.3 39.3 0.75 9.4 18.3 3.1 3 0 0 3 3 3 0 Spt20 family eIF_4EBP PF05456.11 CDJ49173.1 - 6.8 6.7 8.4 5.2 7.0 4.4 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF4667 PF15700.5 CDJ49175.1 - 0.00051 20.2 8.6 0.00058 20.0 8.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ49175.1 - 0.01 15.5 23.8 0.01 15.5 23.8 1.5 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ49175.1 - 3.5 6.3 7.2 4.1 6.1 7.2 1.1 1 0 0 1 1 1 0 Presenilin VWD PF00094.25 CDJ49176.1 - 0.76 10.0 5.3 0.83 9.9 5.3 1.0 1 0 0 1 1 1 0 von Willebrand factor type D domain Bul1_N PF04425.12 CDJ49176.1 - 1.2 7.8 5.3 1.3 7.7 5.3 1.0 1 0 0 1 1 1 0 Bul1 N terminus Pex14_N PF04695.13 CDJ49176.1 - 3.5 8.3 14.4 3.9 8.1 14.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF719 PF05334.13 CDJ49177.1 - 0.084 13.1 10.9 0.096 12.9 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) DUF4820 PF16091.5 CDJ49177.1 - 0.14 11.5 7.7 0.16 11.3 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) HEXIM PF15313.6 CDJ49177.1 - 0.25 11.5 13.5 0.31 11.2 13.5 1.1 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein DUF1980 PF09323.10 CDJ49177.1 - 0.32 10.9 5.7 0.36 10.7 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DDHD PF02862.17 CDJ49177.1 - 0.35 11.0 10.8 0.38 10.9 10.8 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 CDJ49177.1 - 0.37 10.0 5.3 0.39 9.9 5.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NEMP PF10225.9 CDJ49177.1 - 0.53 9.9 2.5 0.66 9.6 2.5 1.1 1 0 0 1 1 1 0 NEMP family TFIIA PF03153.13 CDJ49177.1 - 0.78 9.7 37.0 0.92 9.4 37.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 CDJ49177.1 - 1.1 9.5 15.5 1.3 9.3 15.5 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SID-1_RNA_chan PF13965.6 CDJ49177.1 - 1.2 7.4 2.8 1.3 7.4 2.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PPL5 PF18168.1 CDJ49177.1 - 1.5 8.0 8.2 1.6 7.9 8.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 eIF-3_zeta PF05091.12 CDJ49177.1 - 1.7 7.6 15.0 1.8 7.4 15.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med15 PF09606.10 CDJ49177.1 - 1.8 7.2 32.7 1.9 7.1 32.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MAJIN PF15077.6 CDJ49177.1 - 1.9 8.2 8.5 2 8.1 8.5 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Peptidase_S49_N PF08496.10 CDJ49177.1 - 2.5 8.1 11.1 3.2 7.8 11.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM60A PF15396.6 CDJ49177.1 - 2.8 7.9 11.4 3 7.8 11.4 1.0 1 0 0 1 1 1 0 Protein Family FAM60A SpoIIP PF07454.11 CDJ49177.1 - 3.1 7.2 13.9 3.5 7.0 13.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Ctr PF04145.15 CDJ49177.1 - 3.5 8.2 6.2 4.5 7.9 6.2 1.2 1 0 0 1 1 1 0 Ctr copper transporter family EOS1 PF12326.8 CDJ49177.1 - 3.6 7.5 5.8 4.3 7.2 5.8 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF4228 PF14009.6 CDJ49177.1 - 3.9 7.8 9.9 5.2 7.4 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Neur_chan_memb PF02932.16 CDJ49177.1 - 4.5 7.3 10.0 4.7 7.2 10.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HemX PF04375.14 CDJ49177.1 - 4.9 6.3 30.2 5.3 6.2 30.2 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase RR_TM4-6 PF06459.12 CDJ49177.1 - 4.9 6.9 15.9 5.6 6.7 15.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Roughex PF06020.11 CDJ49177.1 - 4.9 6.2 15.5 5.6 6.0 15.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF3408 PF11888.8 CDJ49177.1 - 4.9 7.3 14.8 6.3 6.9 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Suf PF05843.14 CDJ49177.1 - 5.1 7.0 19.7 5.9 6.8 19.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spore_coat_CotO PF14153.6 CDJ49177.1 - 6 6.8 23.5 8.2 6.3 23.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.17 CDJ49177.1 - 6.4 5.4 19.1 7.5 5.2 19.1 1.0 1 0 0 1 1 1 0 Presenilin R_equi_Vir PF05526.11 CDJ49177.1 - 8.5 6.2 10.7 13 5.6 10.7 1.4 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein TFIIA PF03153.13 CDJ49178.1 - 0.00025 21.2 17.0 0.00027 21.1 17.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ADP_PFK_GK PF04587.15 CDJ49178.1 - 0.00032 19.4 1.4 0.00032 19.4 1.4 1.6 2 0 0 2 2 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region RskA PF10099.9 CDJ49178.1 - 0.00086 19.7 20.0 0.00086 19.7 20.0 2.1 1 1 1 2 2 1 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ49178.1 - 0.0013 19.6 2.4 0.0015 19.5 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF3984 PF13136.6 CDJ49178.1 - 0.0019 17.7 1.7 0.0021 17.5 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Connexin PF00029.19 CDJ49178.1 - 0.0051 16.6 2.7 0.0065 16.3 2.7 1.1 1 0 0 1 1 1 1 Connexin SprA-related PF12118.8 CDJ49178.1 - 0.0092 15.2 18.4 0.012 14.8 18.4 1.1 1 0 0 1 1 1 1 SprA-related family FHIPEP PF00771.20 CDJ49178.1 - 0.0097 14.4 6.2 0.011 14.3 6.2 1.0 1 0 0 1 1 1 1 FHIPEP family DUF2722 PF10846.8 CDJ49178.1 - 0.012 14.7 20.9 0.015 14.3 20.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 CDJ49178.1 - 0.012 15.7 7.9 0.013 15.6 7.9 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ribosomal_S2 PF00318.20 CDJ49178.1 - 0.016 14.5 1.0 0.02 14.1 1.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 Shisa PF13908.6 CDJ49178.1 - 0.019 15.2 9.5 0.024 14.9 9.5 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Suf PF05843.14 CDJ49178.1 - 0.022 14.8 8.3 0.024 14.6 8.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4457 PF14652.6 CDJ49178.1 - 0.024 13.9 0.4 0.025 13.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) DUF1644 PF07800.12 CDJ49178.1 - 0.028 14.5 3.5 0.036 14.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Spt20 PF12090.8 CDJ49178.1 - 0.036 13.7 27.5 0.046 13.3 27.5 1.1 1 0 0 1 1 1 0 Spt20 family DDHD PF02862.17 CDJ49178.1 - 0.038 14.2 3.3 0.039 14.1 3.3 1.1 1 0 0 1 1 1 0 DDHD domain TUSC2 PF15000.6 CDJ49178.1 - 0.077 13.3 3.7 0.13 12.5 3.7 1.3 1 0 0 1 1 1 0 Tumour suppressor candidate 2 DUF1980 PF09323.10 CDJ49178.1 - 0.083 12.8 1.3 0.097 12.6 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) GOLD_2 PF13897.6 CDJ49178.1 - 0.091 13.3 0.4 0.12 12.9 0.4 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Presenilin PF01080.17 CDJ49178.1 - 0.1 11.3 6.3 0.12 11.1 6.3 1.1 1 0 0 1 1 1 0 Presenilin DUF5327 PF17261.2 CDJ49178.1 - 0.12 13.1 13.3 0.19 12.5 13.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Neur_chan_memb PF02932.16 CDJ49178.1 - 0.14 12.2 3.5 0.14 12.2 3.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Roughex PF06020.11 CDJ49178.1 - 0.14 11.3 7.3 0.16 11.0 7.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF3464 PF11947.8 CDJ49178.1 - 0.15 11.8 6.5 0.26 11.0 6.5 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 EOS1 PF12326.8 CDJ49178.1 - 0.17 11.8 0.9 0.19 11.6 0.9 1.2 1 0 0 1 1 1 0 N-glycosylation protein Peroxin-13_N PF04088.13 CDJ49178.1 - 0.19 12.0 4.9 0.28 11.5 4.9 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region V_ATPase_I PF01496.19 CDJ49178.1 - 0.21 9.5 5.4 0.24 9.3 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Activator_LAG-3 PF11498.8 CDJ49178.1 - 0.21 10.5 29.2 0.27 10.2 29.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Serinc PF03348.15 CDJ49178.1 - 0.25 10.2 3.9 0.3 10.0 3.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Tim54 PF11711.8 CDJ49178.1 - 0.26 10.0 6.2 0.33 9.7 6.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3_zeta PF05091.12 CDJ49178.1 - 0.29 10.0 10.2 0.35 9.8 10.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AIF_C PF14721.6 CDJ49178.1 - 0.4 11.0 5.2 0.56 10.6 5.2 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CSG2 PF16965.5 CDJ49178.1 - 0.41 9.5 1.5 0.46 9.4 1.5 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator RIFIN PF02009.16 CDJ49178.1 - 0.42 10.5 9.9 0.56 10.0 9.9 1.1 1 0 0 1 1 1 0 Rifin EIIBC-GUT_N PF03612.14 CDJ49178.1 - 0.51 10.1 7.1 0.76 9.5 7.1 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Orf78 PF06024.12 CDJ49178.1 - 0.54 10.6 4.7 0.94 9.8 4.7 1.3 1 0 0 1 1 1 0 Orf78 (ac78) RNA_pol_Rbc25 PF08292.12 CDJ49178.1 - 0.73 10.1 5.3 1 9.6 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 S_layer_N PF05123.12 CDJ49178.1 - 1.3 8.8 7.1 1.8 8.4 7.1 1.2 1 0 0 1 1 1 0 S-layer like family, N-terminal region RICTOR_N PF14664.6 CDJ49178.1 - 1.6 7.6 4.4 2.1 7.2 4.4 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Sec62 PF03839.16 CDJ49178.1 - 2.1 7.8 6.0 2.7 7.4 6.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Rpp20 PF12328.8 CDJ49178.1 - 2.4 8.1 9.7 3.9 7.4 9.7 1.3 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Peptidase_S49_N PF08496.10 CDJ49178.1 - 2.4 8.2 9.9 0.08 13.0 4.1 1.6 2 0 0 2 2 1 0 Peptidase family S49 N-terminal Band_3_cyto PF07565.13 CDJ49178.1 - 2.5 7.8 8.5 3.2 7.5 8.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain UPF0560 PF10577.9 CDJ49178.1 - 2.5 6.5 14.9 3 6.2 14.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2232 PF09991.9 CDJ49178.1 - 2.9 7.0 13.5 8 5.5 13.5 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4770 PF15994.5 CDJ49178.1 - 3 8.0 11.9 4 7.6 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF2339 PF10101.9 CDJ49178.1 - 3.1 6.3 16.4 4.2 5.8 16.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Coilin_N PF15862.5 CDJ49178.1 - 3.4 7.5 13.0 4.9 6.9 13.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus DUF2681 PF10883.8 CDJ49178.1 - 8.2 6.9 22.9 0.45 10.9 16.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TMEM51 PF15345.6 CDJ49178.1 - 9.4 6.0 12.1 17 5.1 12.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 RskA PF10099.9 CDJ49180.1 - 0.013 15.8 17.2 0.013 15.8 17.2 6.1 1 1 4 5 5 5 0 Anti-sigma-K factor rskA Ribosomal_L27e PF01777.18 CDJ49183.1 - 7.1e-25 87.2 3.4 9.2e-25 86.8 3.4 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CDJ49183.1 - 0.00092 19.1 2.0 0.0017 18.2 2.0 1.4 1 0 0 1 1 1 1 KOW motif rRNA_proc-arch PF13234.6 CDJ49183.1 - 0.016 15.2 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 rRNA-processing arch domain PARP PF00644.20 CDJ49184.1 - 2.8e-53 180.4 0.0 5.1e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CDJ49184.1 - 2.1e-19 70.0 2.1 7.4e-10 39.1 0.1 2.4 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CDJ49184.1 - 8.5e-12 45.0 1.3 2e-11 43.8 1.3 1.7 1 0 0 1 1 1 1 WGR domain PADR1 PF08063.12 CDJ49184.1 - 1.4e-11 44.0 0.1 3.9e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 PADR1 (NUC008) domain BRCT PF00533.26 CDJ49184.1 - 1.7e-09 37.9 0.0 5.5e-09 36.3 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-PARP PF00645.18 CDJ49184.1 - 2.3e-05 25.2 0.0 6.5e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PTCB-BRCT PF12738.7 CDJ49184.1 - 0.0023 17.8 0.0 0.0087 16.0 0.0 2.0 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CDJ49184.1 - 0.016 15.6 0.0 0.079 13.4 0.0 2.1 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain DUF2970 PF11174.8 CDJ49186.1 - 0.0067 16.3 0.3 0.022 14.6 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2970) CYYR1 PF10873.8 CDJ49186.1 - 0.045 14.2 0.2 0.088 13.2 0.2 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Prominin PF05478.11 CDJ49186.1 - 0.12 10.3 0.0 0.18 9.8 0.0 1.2 1 0 0 1 1 1 0 Prominin OAD_gamma PF04277.13 CDJ49186.1 - 0.12 13.0 0.6 0.27 11.9 0.0 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Shisa PF13908.6 CDJ49186.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 CDJ49186.1 - 0.21 11.4 5.4 0.37 10.6 5.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4518 PF15008.6 CDJ49187.1 - 4.8 6.3 7.8 0.13 11.4 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) Methyltransf_16 PF10294.9 CDJ49188.1 - 3.5e-06 26.9 0.0 0.0061 16.3 0.0 2.7 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 CDJ49188.1 - 2.1e-05 24.2 0.2 8.6e-05 22.1 0.2 2.0 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CDJ49188.1 - 2.5e-05 24.2 0.2 2.5e-05 24.2 0.2 3.0 1 1 1 2 2 2 1 Methyltransferase domain LCD1 PF09798.9 CDJ49188.1 - 0.0023 16.5 5.2 0.59 8.6 0.0 2.3 2 1 0 2 2 1 1 DNA damage checkpoint protein PrmA PF06325.13 CDJ49188.1 - 0.0031 17.0 0.0 0.0031 17.0 0.0 2.5 3 0 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) Spore_YhcN_YlaJ PF09580.10 CDJ49188.1 - 0.084 13.0 0.3 0.084 13.0 0.3 2.4 2 1 0 2 2 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF3801 PF12687.7 CDJ49188.1 - 0.11 12.6 14.2 0.17 12.0 7.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) MAT1 PF06391.13 CDJ49188.1 - 0.51 10.1 22.7 0.22 11.3 14.0 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 ANAPC_CDC26 PF10471.9 CDJ49188.1 - 0.54 11.1 47.8 4.3 8.3 7.2 4.0 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 AUX_IAA PF02309.16 CDJ49188.1 - 0.64 9.8 7.9 0.38 10.6 2.1 2.3 2 0 0 2 2 2 0 AUX/IAA family Het-C PF07217.11 CDJ49188.1 - 3.2 6.2 11.1 0.32 9.5 6.0 1.7 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C SMYLE_N PF18615.1 CDJ49188.1 - 3.5 7.1 13.5 1.1 8.7 5.2 2.2 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF1676 PF07898.13 CDJ49188.1 - 5 7.1 6.2 2.7 8.0 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) DNApol_Exo PF18136.1 CDJ49188.1 - 5.1 6.2 13.3 3.4 6.7 8.2 2.1 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain FHIPEP PF00771.20 CDJ49188.1 - 6.4 5.1 14.6 6.3 5.1 7.1 2.2 2 0 0 2 2 2 0 FHIPEP family Band_3_cyto PF07565.13 CDJ49188.1 - 8 6.2 15.0 13 5.5 10.5 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain XK-related PF09815.9 CDJ49188.1 - 8.7 5.3 5.4 6 5.8 0.2 2.2 2 0 0 2 2 2 0 XK-related protein EPL1 PF10513.9 CDJ49189.1 - 0.00041 20.8 7.1 0.26 11.7 6.8 2.3 2 0 0 2 2 2 2 Enhancer of polycomb-like ODV-E18 PF10717.9 CDJ49189.1 - 0.021 14.7 0.2 0.021 14.7 0.2 3.0 2 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF1676 PF07898.13 CDJ49189.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Eapp_C PF10238.9 CDJ49189.1 - 1.7 8.7 10.0 0.56 10.3 4.1 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein CDC45 PF02724.14 CDJ49189.1 - 2 6.6 7.7 26 2.9 7.6 2.1 2 0 0 2 2 2 0 CDC45-like protein Rxt3 PF08642.10 CDJ49189.1 - 8.2 7.2 8.4 67 4.3 5.2 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Gti1_Pac2 PF09729.9 CDJ49189.1 - 8.3 6.5 15.4 1.8 8.6 3.8 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family DUF2457 PF10446.9 CDJ49191.1 - 0.031 13.4 33.1 0.038 13.1 33.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.12 CDJ49191.1 - 0.89 8.1 38.7 1.1 7.8 38.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 CDJ49191.1 - 1.2 7.3 39.0 1.3 7.1 39.0 1.0 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 CDJ49191.1 - 1.4 8.4 49.4 1.7 8.2 49.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Plasmodium_Vir PF05795.11 CDJ49191.1 - 2 7.7 24.9 2.7 7.3 24.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_S64 PF08192.11 CDJ49191.1 - 3.1 6.2 37.3 3.8 5.9 37.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 PAP1 PF08601.10 CDJ49191.1 - 4.3 7.0 34.7 5.3 6.7 34.7 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 CDC45 PF02724.14 CDJ49191.1 - 4.3 5.5 44.6 5.4 5.2 44.6 1.0 1 0 0 1 1 1 0 CDC45-like protein LTV PF04180.14 CDJ49191.1 - 9.9 5.8 36.5 13 5.4 36.5 1.1 1 0 0 1 1 1 0 Low temperature viability protein Myosin_head PF00063.21 CDJ49192.1 - 1.7e-150 502.5 7.4 2.6e-142 475.4 0.1 2.9 2 1 1 3 3 3 2 Myosin head (motor domain) TFIIA PF03153.13 CDJ49192.1 - 0.0047 17.0 7.0 0.0082 16.2 7.0 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ49192.1 - 0.0058 15.4 7.7 0.0083 14.9 7.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ49192.1 - 0.012 15.2 13.4 0.024 14.3 13.4 1.4 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ49192.1 - 0.021 15.1 0.2 0.16 12.2 0.1 2.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ49192.1 - 0.11 13.5 6.7 0.37 11.8 6.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AAA_16 PF13191.6 CDJ49192.1 - 0.16 12.4 0.0 0.16 12.4 0.0 3.3 2 1 0 3 3 3 0 AAA ATPase domain Hydin_ADK PF17213.3 CDJ49192.1 - 0.22 11.8 4.5 9.1 6.5 1.3 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 CDJ49192.1 - 0.3 11.4 3.7 0.77 10.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF2722 PF10846.8 CDJ49192.1 - 1.2 8.0 12.8 1.9 7.3 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF775 PF05603.12 CDJ49192.1 - 2.7 7.5 10.6 4.9 6.6 6.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF775) AAA PF00004.29 CDJ49193.1 - 2.1e-12 47.6 1.9 1.4e-06 28.8 0.0 3.6 3 1 1 4 4 4 2 ATPase family associated with various cellular activities (AAA) SR-25 PF10500.9 CDJ49195.1 - 0.069 12.7 71.7 0.87 9.1 23.5 3.5 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein ETRAMP PF09716.10 CDJ49195.1 - 0.15 12.1 0.2 0.15 12.1 0.2 3.5 5 0 0 5 5 5 0 Malarial early transcribed membrane protein (ETRAMP) Spt20 PF12090.8 CDJ49195.1 - 0.16 11.6 97.4 0.35 10.5 39.9 3.3 3 0 0 3 3 3 0 Spt20 family DUF2052 PF09747.9 CDJ49195.1 - 0.19 11.9 29.8 1.8 8.6 0.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) MAP7 PF05672.11 CDJ49196.1 - 0.0012 18.6 35.8 0.0016 18.2 35.8 1.2 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family SR-25 PF10500.9 CDJ49196.1 - 0.013 15.1 37.6 0.041 13.5 29.8 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 CDJ49196.1 - 0.22 11.0 32.7 0.26 10.8 32.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist HemX PF04375.14 CDJ49196.1 - 0.25 10.6 38.7 0.39 9.9 38.7 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase eIF-3_zeta PF05091.12 CDJ49196.1 - 0.89 8.5 28.0 1.3 7.9 28.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Miga PF10265.9 CDJ49196.1 - 1.2 8.1 20.2 1.3 7.9 20.2 1.1 1 0 0 1 1 1 0 Mitoguardin SAGA-Tad1 PF12767.7 CDJ49196.1 - 1.4 8.6 22.9 1.5 8.5 22.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PNISR PF15996.5 CDJ49196.1 - 1.6 9.0 33.1 2 8.6 33.1 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR GREB1 PF15782.5 CDJ49196.1 - 1.9 5.5 36.9 2.1 5.4 36.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDJ49196.1 - 2.1 6.8 27.1 2.5 6.6 27.1 1.1 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 CDJ49196.1 - 2.8 6.1 25.2 3.4 5.8 25.2 1.2 1 0 0 1 1 1 0 CDC45-like protein CCSAP PF15748.5 CDJ49196.1 - 3.4 7.8 34.4 4.4 7.4 34.4 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated VIR_N PF15912.5 CDJ49196.1 - 4.7 6.7 12.7 5.8 6.4 12.7 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal SLC12 PF03522.15 CDJ49196.1 - 6.2 5.7 28.9 7.6 5.4 28.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 MMU163 PF17119.5 CDJ49196.1 - 7.1 5.7 19.3 11 5.0 19.1 1.4 1 1 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis SR-25 PF10500.9 CDJ49197.1 - 2.6e-05 24.0 16.5 2.6e-05 24.0 16.5 5.3 5 0 0 5 5 5 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ49197.1 - 7.9e-05 23.0 1.2 7.9e-05 23.0 1.2 7.1 3 1 2 5 5 5 2 Anti-sigma-K factor rskA TAF4 PF05236.14 CDJ49197.1 - 0.0015 18.4 0.9 0.0015 18.4 0.9 6.9 4 2 3 7 7 7 1 Transcription initiation factor TFIID component TAF4 family DXP_synthase_N PF13292.6 CDJ49198.1 - 1.2e-49 169.0 0.1 1.2e-49 169.0 0.1 3.5 3 1 1 4 4 4 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 CDJ49198.1 - 8.1e-33 113.6 2.2 7.3e-27 94.2 0.3 4.7 3 1 1 4 4 4 2 Transketolase, pyrimidine binding domain DUF2722 PF10846.8 CDJ49198.1 - 0.0034 16.4 2.6 0.0056 15.7 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ49198.1 - 0.59 9.7 13.6 0.99 9.0 13.6 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ49198.1 - 2.6 8.0 6.0 0.22 11.5 0.4 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 CDJ49198.1 - 7.4 7.6 5.3 15 6.6 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AAA_16 PF13191.6 CDJ49199.1 - 1.9e-07 31.6 1.7 1.9e-07 31.6 1.7 3.6 3 1 1 4 4 4 1 AAA ATPase domain AAA_35 PF14516.6 CDJ49199.1 - 0.0004 19.3 0.0 0.24 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain ATPase_2 PF01637.18 CDJ49199.1 - 0.00051 20.0 0.0 0.014 15.3 0.0 2.7 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CDJ49199.1 - 0.0093 16.2 1.6 0.03 14.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CDJ49199.1 - 0.044 13.7 1.1 0.071 13.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 CDJ49199.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDJ49199.1 - 2.4 8.5 6.1 0.35 11.2 0.1 2.7 1 1 1 2 2 2 0 AAA domain Metallophos PF00149.28 CDJ49200.1 - 1.5e-28 100.7 0.1 1.8e-28 100.5 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ49200.1 - 0.011 16.0 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 CDJ49200.1 - 0.015 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Spt20 PF12090.8 CDJ49201.1 - 0.0036 16.9 14.2 0.0036 16.9 14.2 2.2 2 0 0 2 2 2 1 Spt20 family SPX PF03105.19 CDJ49201.1 - 0.1 12.5 20.9 0.13 12.2 20.9 1.1 1 0 0 1 1 1 0 SPX domain Ribosomal_60s PF00428.19 CDJ49201.1 - 1.9 9.1 16.9 26 5.5 14.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2722 PF10846.8 CDJ49201.1 - 5 5.9 59.9 0.013 14.5 12.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) FAM184 PF15665.5 CDJ49202.1 - 0.01 15.7 0.2 0.011 15.5 0.2 1.0 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B SPO11_like PF03533.14 CDJ49202.1 - 0.022 14.9 0.2 45 4.2 0.0 3.3 3 0 0 3 3 3 0 SPO11 homologue RIC1 PF07064.13 CDJ49202.1 - 0.072 12.5 0.3 22 4.3 0.0 3.0 1 1 2 3 3 3 0 RIC1 Apt1 PF10351.9 CDJ49203.1 - 0.0028 16.6 16.1 0.0028 16.6 16.1 2.4 1 1 1 2 2 2 2 Golgi-body localisation protein domain DAG_kinase_N PF14513.6 CDJ49203.1 - 0.0033 17.7 10.8 0.0033 17.7 10.8 3.7 3 1 0 3 3 3 1 Diacylglycerol kinase N-terminus TMEM51 PF15345.6 CDJ49203.1 - 0.0045 16.9 5.9 0.0045 16.9 5.9 4.2 2 1 2 4 4 4 1 Transmembrane protein 51 Presenilin PF01080.17 CDJ49203.1 - 0.0046 15.8 7.1 0.0046 15.8 7.1 3.1 3 0 0 3 3 3 2 Presenilin rRNA_processing PF08524.11 CDJ49203.1 - 0.0052 16.8 2.1 0.0052 16.8 2.1 3.4 3 0 0 3 3 3 1 rRNA processing RED_N PF07808.13 CDJ49203.1 - 0.007 16.0 2.0 0.007 16.0 2.0 3.9 3 1 1 4 4 4 1 RED-like protein N-terminal region U1snRNP70_N PF12220.8 CDJ49203.1 - 0.016 15.9 1.9 0.016 15.9 1.9 4.2 3 1 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RskA PF10099.9 CDJ49203.1 - 0.024 15.0 1.1 0.024 15.0 1.1 4.9 1 1 2 3 3 3 0 Anti-sigma-K factor rskA Connexin PF00029.19 CDJ49203.1 - 0.1 12.4 34.7 0.24 11.1 1.7 3.2 3 0 0 3 3 3 0 Connexin CAC1F_C PF16885.5 CDJ49203.1 - 4.4 6.9 35.2 0.94 9.1 20.9 2.3 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term ATP-synt_DE_N PF02823.16 CDJ49204.1 - 2.3e-07 30.6 0.0 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Dehydrin PF00257.19 CDJ49204.1 - 0.21 12.1 3.5 0.43 11.1 3.5 1.4 1 0 0 1 1 1 0 Dehydrin DUF755 PF05501.11 CDJ49204.1 - 0.53 10.6 12.9 7.8 6.8 7.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ49204.1 - 0.64 9.6 5.3 1.1 8.8 5.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein hDGE_amylase PF14701.6 CDJ49205.1 - 5.3e-129 431.1 0.6 1.4e-128 429.8 0.0 1.8 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain hGDE_central PF14702.6 CDJ49205.1 - 8.1e-28 97.8 0.0 2.2e-27 96.4 0.0 1.7 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme GDE_C PF06202.14 CDJ49205.1 - 1.1e-18 67.3 3.8 7e-17 61.4 2.3 2.4 2 1 1 3 3 3 2 Amylo-alpha-1,6-glucosidase SUIM_assoc PF16619.5 CDJ49205.1 - 0.0063 16.6 0.5 0.0063 16.6 0.5 5.2 4 1 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 DUF2228 PF10228.9 CDJ49206.1 - 3e-16 59.9 0.3 3e-16 59.9 0.3 5.8 4 2 2 6 6 6 1 Uncharacterised conserved protein (DUF2228) Presenilin PF01080.17 CDJ49206.1 - 0.0005 19.0 29.3 0.0005 19.0 29.3 3.7 2 1 0 2 2 2 1 Presenilin BUD22 PF09073.10 CDJ49206.1 - 0.0019 17.6 32.3 0.0019 17.6 32.3 3.8 1 1 0 3 3 3 1 BUD22 DUF2722 PF10846.8 CDJ49206.1 - 0.0023 16.9 10.3 0.0023 16.9 10.3 5.1 3 2 0 4 4 4 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ49206.1 - 0.0057 16.3 12.5 0.0057 16.3 12.5 4.6 3 2 0 3 3 3 1 Spt20 family LPMO_10 PF03067.15 CDJ49206.1 - 0.026 15.2 22.2 0.058 14.0 15.8 2.8 2 0 0 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading eIF-3_zeta PF05091.12 CDJ49206.1 - 0.078 11.9 47.0 0.32 9.9 36.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med15 PF09606.10 CDJ49206.1 - 1.2 7.7 87.9 0.028 13.1 9.0 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Macoilin PF09726.9 CDJ49209.1 - 4.5 5.7 38.3 5.7 5.4 38.3 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CDJ49210.1 - 0.11 11.2 2.8 0.15 10.8 2.8 1.3 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 CDJ49210.1 - 0.14 12.5 3.5 0.41 11.0 3.5 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Vps39_2 PF10367.9 CDJ49210.1 - 0.17 12.4 2.7 0.29 11.6 2.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF2459 PF09601.10 CDJ49210.1 - 0.32 10.8 1.3 0.62 9.8 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) SpoIIP PF07454.11 CDJ49210.1 - 0.37 10.2 7.3 0.58 9.6 7.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Peptidase_U57 PF05582.12 CDJ49210.1 - 0.42 9.8 4.8 0.62 9.3 4.8 1.1 1 0 0 1 1 1 0 YabG peptidase U57 PIG-S PF10510.9 CDJ49210.1 - 0.44 9.3 6.6 0.75 8.6 6.6 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Rpp20 PF12328.8 CDJ49210.1 - 1.3 9.0 5.1 2.6 8.0 5.1 1.4 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P TFIIA PF03153.13 CDJ49210.1 - 3.1 7.7 29.8 0.24 11.3 22.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ49210.1 - 3.8 8.5 7.2 8.7 7.4 7.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2924 PF11149.8 CDJ49210.1 - 3.9 7.9 8.3 8.6 6.8 8.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Tim54 PF11711.8 CDJ49210.1 - 4.1 6.1 8.6 0.54 9.0 4.6 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 CDJ49211.1 - 0.12 11.6 25.3 0.14 11.4 25.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Kei1 PF08552.11 CDJ49211.1 - 0.55 10.1 18.7 0.82 9.5 18.7 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Rtf2 PF04641.12 CDJ49211.1 - 0.89 8.9 26.9 1 8.7 26.9 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger FAM76 PF16046.5 CDJ49211.1 - 0.96 8.7 32.8 1.2 8.5 32.8 1.1 1 0 0 1 1 1 0 FAM76 protein Pox_Ag35 PF03286.14 CDJ49211.1 - 1.1 9.0 16.7 1.3 8.8 16.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM60A PF15396.6 CDJ49211.1 - 1.2 9.1 24.9 1.3 8.9 24.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Gti1_Pac2 PF09729.9 CDJ49211.1 - 1.3 9.0 27.3 1.7 8.7 27.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4746 PF15928.5 CDJ49211.1 - 1.6 8.1 22.6 1.8 7.9 22.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) HCO3_cotransp PF00955.21 CDJ49211.1 - 1.8 7.3 16.3 1.8 7.3 16.3 1.0 1 0 0 1 1 1 0 HCO3- transporter family RR_TM4-6 PF06459.12 CDJ49211.1 - 2 8.2 34.0 2.4 7.9 34.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ49211.1 - 2.1 8.3 26.8 2.2 8.2 26.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2828 PF11443.8 CDJ49211.1 - 2.2 6.2 28.6 2.6 6.0 28.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CDC45 PF02724.14 CDJ49211.1 - 2.3 6.4 28.3 2.6 6.2 28.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 CDJ49211.1 - 2.4 7.1 18.1 3 6.7 18.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDRGK PF09756.9 CDJ49211.1 - 2.9 7.5 39.9 3.6 7.1 39.9 1.1 1 0 0 1 1 1 0 DDRGK domain DUF2370 PF10176.9 CDJ49211.1 - 3.3 7.3 16.4 4.2 7.0 16.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4638 PF15472.6 CDJ49211.1 - 3.5 7.3 29.8 4 7.1 29.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) AAA_11 PF13086.6 CDJ49211.1 - 3.9 7.2 29.6 4.1 7.1 29.6 1.0 1 0 0 1 1 1 0 AAA domain DUF2052 PF09747.9 CDJ49211.1 - 4 7.5 30.6 4.4 7.4 30.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SLC12 PF03522.15 CDJ49211.1 - 4.2 6.3 34.1 4.9 6.1 34.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Vfa1 PF08432.10 CDJ49211.1 - 4.4 7.6 33.4 5.4 7.3 33.4 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Endostatin PF06482.11 CDJ49211.1 - 4.6 6.6 30.8 4.9 6.5 30.8 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF5427 PF10310.9 CDJ49211.1 - 4.8 6.0 33.3 5.7 5.8 33.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF3295 PF11702.8 CDJ49211.1 - 4.9 6.4 27.1 5.4 6.3 27.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) LAP1C PF05609.12 CDJ49211.1 - 5.2 6.0 32.0 5.6 5.9 32.0 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ALMT PF11744.8 CDJ49211.1 - 5.6 5.7 27.7 6.3 5.5 27.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Paramyxo_ncap PF00973.19 CDJ49211.1 - 5.9 5.7 25.0 6.2 5.6 25.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CLN3 PF02487.17 CDJ49211.1 - 5.9 5.8 24.3 7.1 5.6 24.3 1.1 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 CDJ49211.1 - 6.3 5.4 38.5 7.9 5.1 38.5 1.0 1 0 0 1 1 1 0 Presenilin DAG_kinase_N PF14513.6 CDJ49211.1 - 6.7 6.9 28.7 7.9 6.7 28.7 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus HGTP_anticodon2 PF12745.7 CDJ49211.1 - 7.4 6.0 31.1 9.4 5.6 31.1 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs SelP_N PF04592.14 CDJ49211.1 - 9.1 5.6 41.8 13 5.2 41.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF572 PF04502.13 CDJ49211.1 - 9.6 5.7 28.0 11 5.5 28.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) BORG_CEP PF14957.6 CDJ49211.1 - 9.6 7.4 21.7 14 6.9 21.7 1.2 1 0 0 1 1 1 0 Cdc42 effector DUF4050 PF13259.6 CDJ49211.1 - 9.8 6.5 28.2 12 6.2 28.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) TCP PF03634.13 CDJ49212.1 - 0.028 15.0 23.0 0.034 14.7 23.0 1.1 1 0 0 1 1 1 0 TCP family transcription factor DUF2126 PF09899.9 CDJ49212.1 - 0.13 10.3 10.8 0.13 10.4 10.8 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SprA-related PF12118.8 CDJ49212.1 - 0.23 10.6 32.8 0.27 10.3 32.8 1.1 1 0 0 1 1 1 0 SprA-related family eIF-3_zeta PF05091.12 CDJ49212.1 - 0.57 9.1 21.4 0.67 8.9 21.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MAP70 PF07058.11 CDJ49212.1 - 0.63 8.7 14.6 0.66 8.7 14.6 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 Presenilin PF01080.17 CDJ49212.1 - 0.79 8.4 26.9 0.9 8.2 26.9 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CDJ49212.1 - 0.84 8.9 12.9 0.86 8.9 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5385 PF17359.2 CDJ49212.1 - 1.3 8.5 14.6 2 7.9 14.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) CCSAP PF15748.5 CDJ49212.1 - 1.7 8.8 29.9 2.2 8.4 29.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4175 PF13779.6 CDJ49212.1 - 1.8 6.4 29.9 1.8 6.4 29.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PA26 PF04636.13 CDJ49212.1 - 2.6 6.9 14.4 3.1 6.6 14.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SR-25 PF10500.9 CDJ49212.1 - 3.6 7.1 40.5 12 5.4 40.5 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.16 CDJ49212.1 - 6 6.9 19.5 8.2 6.4 19.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_TAF50 PF03326.13 CDJ49212.1 - 6 5.4 32.3 7 5.2 32.3 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) PAT1 PF09770.9 CDJ49212.1 - 6.5 4.9 29.5 7.7 4.6 29.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.14 CDJ49212.1 - 8.5 6.3 27.7 12 5.8 27.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM199X PF15814.5 CDJ49212.1 - 9.7 5.1 23.5 11 4.9 23.5 1.1 1 0 0 1 1 1 0 Protein family FAM199X MgtE PF01769.16 CDJ49213.1 - 0.0075 16.6 0.2 0.011 16.2 0.2 1.1 1 0 0 1 1 1 1 Divalent cation transporter TFIIA PF03153.13 CDJ49213.1 - 0.062 13.3 23.1 0.088 12.8 23.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ49213.1 - 0.13 11.8 15.9 0.21 11.2 15.9 1.4 1 0 0 1 1 1 0 Spt20 family DUF572 PF04502.13 CDJ49213.1 - 0.27 10.8 15.3 0.33 10.5 15.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4778 PF16008.5 CDJ49213.1 - 0.94 9.5 9.8 0.99 9.4 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Draxin PF15550.6 CDJ49213.1 - 0.97 9.2 8.3 1.3 8.9 8.3 1.2 1 0 0 1 1 1 0 Draxin SWI-SNF_Ssr4 PF08549.10 CDJ49213.1 - 6.2 5.3 14.5 6.8 5.2 14.5 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SAP130_C PF16014.5 CDJ49213.1 - 7.5 5.5 23.6 9.4 5.2 23.6 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus RR_TM4-6 PF06459.12 CDJ49213.1 - 8.7 6.1 10.3 12 5.6 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NUDE_C PF04880.13 CDJ49213.1 - 9.9 6.6 19.0 13 6.2 19.0 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PP2C PF00481.21 CDJ49214.1 - 1.4e-12 47.9 0.0 4e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Protein phosphatase 2C ALMT PF11744.8 CDJ49214.1 - 0.85 8.4 6.9 1.8 7.3 6.9 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2722 PF10846.8 CDJ49215.1 - 0.01 14.8 1.7 0.012 14.7 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TCP PF03634.13 CDJ49215.1 - 0.026 15.1 0.7 0.038 14.6 0.7 1.2 1 0 0 1 1 1 0 TCP family transcription factor Spt20 PF12090.8 CDJ49215.1 - 3.4 7.2 15.4 4.8 6.7 15.4 1.1 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ49215.1 - 6.9 5.5 18.1 8.6 5.2 18.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PRP1_N PF06424.12 CDJ49216.1 - 0.5 10.7 30.1 0.61 10.5 30.1 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal PA26 PF04636.13 CDJ49216.1 - 4.6 6.1 26.7 4.9 5.9 26.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) cNMP_binding PF00027.29 CDJ49217.1 - 9.9e-08 32.0 8.0 0.051 13.6 0.1 4.8 4 2 0 4 4 4 3 Cyclic nucleotide-binding domain DUF4667 PF15700.5 CDJ49217.1 - 0.0013 18.9 0.8 0.0013 18.9 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ49217.1 - 0.016 15.2 8.4 0.45 10.4 1.8 2.1 2 0 0 2 2 2 0 SPX domain Apt1 PF10351.9 CDJ49217.1 - 0.017 14.0 8.4 0.42 9.4 0.4 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ49217.1 - 0.034 13.7 43.4 0.074 12.7 19.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein OATP PF03137.20 CDJ49217.1 - 0.38 9.0 4.5 0.47 8.7 2.8 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cloacin PF03515.14 CDJ49217.1 - 1.2 8.8 10.0 0.11 12.2 1.3 2.5 2 1 0 2 2 2 0 Colicin-like bacteriocin tRNase domain PAP1 PF08601.10 CDJ49217.1 - 1.3 8.7 20.9 1.7 8.3 6.7 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 DUF4614 PF15391.6 CDJ49217.1 - 2.4 8.1 22.7 3 7.8 6.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Presenilin PF01080.17 CDJ49217.1 - 3.3 6.4 7.0 6.4 5.4 4.0 2.0 2 0 0 2 2 2 0 Presenilin EBP50_C PF09007.11 CDJ49217.1 - 3.7 8.5 18.1 7.5 7.6 7.3 2.3 2 0 0 2 2 2 0 EBP50, C-terminal CCDC24 PF15669.5 CDJ49217.1 - 3.9 7.3 14.4 0.078 12.8 0.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Lin-8 PF03353.15 CDJ49217.1 - 4.5 6.8 13.2 6.5 6.2 6.6 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF1635 PF07795.11 CDJ49217.1 - 7.1 6.4 21.5 1.8 8.4 8.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) SARAF PF06682.12 CDJ49218.1 - 3.6e-05 23.6 6.8 3.6e-05 23.6 6.8 15.0 9 3 6 15 15 15 1 SOCE-associated regulatory factor of calcium homoeostasis RskA PF10099.9 CDJ49218.1 - 0.005 17.1 10.4 0.005 17.1 10.4 20.2 5 5 6 11 11 11 1 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ49219.1 - 0.11 13.0 1.1 0.2 12.2 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Activator_LAG-3 PF11498.8 CDJ49219.1 - 7.9 5.3 27.2 11 4.9 27.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RskA PF10099.9 CDJ49220.1 - 0.0022 18.3 29.4 0.0022 18.3 29.4 10.8 3 2 4 7 7 7 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ49221.1 - 0.00052 19.7 9.1 0.00052 19.7 9.1 10.2 6 3 4 10 10 10 2 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 CDJ49221.1 - 0.0025 16.0 1.0 0.0025 16.0 1.0 5.5 2 2 2 4 4 4 1 Sporozoite P67 surface antigen BUD22 PF09073.10 CDJ49221.1 - 0.0096 15.3 0.0 0.0096 15.3 0.0 5.4 2 2 3 5 5 5 2 BUD22 Capsid_NCLDV PF04451.12 CDJ49222.1 - 0.073 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein YokU PF14122.6 CDJ49222.1 - 1.8 8.6 3.8 0.89 9.6 1.1 1.8 2 0 0 2 2 2 0 YokU-like protein, putative antitoxin Utp14 PF04615.13 CDJ49223.1 - 0.077 11.6 46.5 0.0086 14.7 36.5 2.2 2 0 0 2 2 2 0 Utp14 protein PS_Dcarbxylase PF02666.15 CDJ49224.1 - 2.7e-37 128.3 0.0 3.3e-37 128.0 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase RskA PF10099.9 CDJ49224.1 - 0.00043 20.6 6.6 0.00064 20.1 6.6 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ49224.1 - 0.005 16.5 24.0 0.0075 15.9 24.0 1.3 1 0 0 1 1 1 1 Spt20 family Suf PF05843.14 CDJ49224.1 - 0.008 16.2 7.3 0.01 15.9 7.3 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Velvet PF11754.8 CDJ49224.1 - 0.014 15.4 5.0 0.017 15.1 5.0 1.1 1 0 0 1 1 1 0 Velvet factor TFIIA PF03153.13 CDJ49224.1 - 0.16 11.9 27.0 0.21 11.5 27.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ49224.1 - 0.4 11.3 17.0 0.68 10.6 17.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.12 CDJ49224.1 - 0.73 8.7 7.9 0.9 8.4 7.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3464 PF11947.8 CDJ49224.1 - 0.9 9.3 6.8 1.6 8.4 6.8 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SARAF PF06682.12 CDJ49224.1 - 1.2 8.8 11.4 1.6 8.3 11.4 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4407 PF14362.6 CDJ49224.1 - 1.3 8.4 8.0 1.8 7.9 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TCP PF03634.13 CDJ49224.1 - 1.6 9.3 9.1 2.5 8.7 9.1 1.2 1 0 0 1 1 1 0 TCP family transcription factor DUF4834 PF16118.5 CDJ49224.1 - 1.7 9.6 8.0 2.8 9.0 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Activator_LAG-3 PF11498.8 CDJ49224.1 - 4.2 6.2 28.5 6.3 5.7 28.5 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HA2 PF04408.23 CDJ49224.1 - 4.7 7.6 6.7 12 6.2 6.7 1.7 1 1 0 1 1 1 0 Helicase associated domain (HA2) DUF4813 PF16072.5 CDJ49225.1 - 0.0013 18.5 23.9 0.0016 18.1 23.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4813) RskA PF10099.9 CDJ49225.1 - 0.0029 17.9 30.8 0.0098 16.2 31.2 1.6 1 1 1 2 2 2 1 Anti-sigma-K factor rskA RAP1 PF07218.11 CDJ49225.1 - 0.0047 15.3 5.9 0.0047 15.3 5.9 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Med3 PF11593.8 CDJ49225.1 - 0.037 13.2 31.0 0.05 12.8 31.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med15 PF09606.10 CDJ49225.1 - 0.11 11.1 22.2 0.11 11.2 22.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AF-4 PF05110.13 CDJ49225.1 - 0.37 8.8 29.8 0.54 8.3 29.8 1.2 1 1 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ49225.1 - 0.47 10.0 23.8 0.23 11.0 17.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ49225.1 - 0.78 8.4 8.4 1 8.1 8.4 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ49225.1 - 2 8.3 27.4 2.4 8.1 27.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Secretin_N_2 PF07655.13 CDJ49225.1 - 3.6 8.2 16.8 0.32 11.6 10.1 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain DUF1631 PF07793.11 CDJ49225.1 - 4.4 5.6 27.7 4.9 5.5 27.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Lin-8 PF03353.15 CDJ49225.1 - 8.2 5.9 14.8 1.6 8.2 1.6 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TIP49 PF06068.13 CDJ49226.1 - 1.3e-43 149.6 0.2 1.5e-43 149.4 0.2 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain Raco_middle PF17651.1 CDJ49226.1 - 0.04 13.6 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 RACo middle region Pkinase PF00069.25 CDJ49227.1 - 3.3e-10 39.8 0.0 5e-08 32.6 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ49227.1 - 0.00032 20.1 0.0 0.00066 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase XRN_N PF03159.18 CDJ49228.1 - 5.4e-28 98.1 1.5 9e-28 97.3 1.5 1.4 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF5308 PF17233.2 CDJ49228.1 - 0.00053 20.2 2.0 0.00066 19.9 2.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5308) CNDH2_C PF16858.5 CDJ49228.1 - 0.00084 19.3 1.8 0.00094 19.1 1.8 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term SpoIIP PF07454.11 CDJ49228.1 - 0.0016 18.0 1.2 0.0016 18.0 1.2 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 CDJ49228.1 - 0.0018 18.3 10.8 0.0018 18.3 10.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit OATP PF03137.20 CDJ49228.1 - 0.0034 15.7 0.1 0.0041 15.5 0.1 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Presenilin PF01080.17 CDJ49228.1 - 0.005 15.7 0.8 0.005 15.7 0.8 1.1 1 0 0 1 1 1 1 Presenilin RR_TM4-6 PF06459.12 CDJ49228.1 - 0.0082 16.0 1.3 0.0082 16.0 1.3 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 tRNA_synt_1c_R2 PF04557.15 CDJ49228.1 - 0.014 16.3 3.9 0.026 15.4 3.9 1.4 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Neur_chan_memb PF02932.16 CDJ49228.1 - 0.016 15.2 1.4 0.019 15.0 1.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FHIPEP PF00771.20 CDJ49228.1 - 0.018 13.5 0.2 0.018 13.5 0.2 1.1 1 0 0 1 1 1 0 FHIPEP family DDHD PF02862.17 CDJ49228.1 - 0.025 14.8 0.6 0.025 14.8 0.6 1.1 1 0 0 1 1 1 0 DDHD domain RPA43_OB PF17875.1 CDJ49228.1 - 0.029 15.0 1.5 0.035 14.7 1.5 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I SUV3_C PF12513.8 CDJ49228.1 - 0.031 14.2 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Suf PF05843.14 CDJ49228.1 - 0.033 14.2 3.7 0.035 14.1 3.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4820 PF16091.5 CDJ49228.1 - 0.034 13.5 3.7 0.05 13.0 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4770 PF15994.5 CDJ49228.1 - 0.039 14.2 3.1 0.042 14.1 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) V_ATPase_I PF01496.19 CDJ49228.1 - 0.048 11.6 2.5 0.048 11.6 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ARF7EP_C PF14949.6 CDJ49228.1 - 0.048 14.3 5.8 0.071 13.7 5.8 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus DUF2722 PF10846.8 CDJ49228.1 - 0.053 12.5 16.0 0.061 12.3 16.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Peroxin-13_N PF04088.13 CDJ49228.1 - 0.06 13.6 1.0 0.1 12.9 1.0 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region CLN3 PF02487.17 CDJ49228.1 - 0.085 11.9 0.4 0.092 11.8 0.4 1.1 1 0 0 1 1 1 0 CLN3 protein UPF0560 PF10577.9 CDJ49228.1 - 0.087 11.3 7.9 0.092 11.2 7.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MCD PF05292.11 CDJ49228.1 - 0.11 12.1 1.2 0.15 11.6 1.2 1.1 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain MscS_TM PF12794.7 CDJ49228.1 - 0.11 11.3 4.5 0.036 12.9 1.5 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF3408 PF11888.8 CDJ49228.1 - 0.11 12.6 8.2 0.17 12.0 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) MDM31_MDM32 PF08118.11 CDJ49228.1 - 0.13 10.9 2.5 0.18 10.4 2.5 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins FAM176 PF14851.6 CDJ49228.1 - 0.14 11.8 3.3 0.18 11.5 3.3 1.2 1 0 0 1 1 1 0 FAM176 family TFB6 PF17110.5 CDJ49228.1 - 0.2 11.4 7.4 0.35 10.6 7.4 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH AIF_C PF14721.6 CDJ49228.1 - 0.26 11.6 3.4 0.4 11.1 3.4 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Fmp27 PF10344.9 CDJ49228.1 - 0.36 8.9 1.5 0.37 8.8 1.5 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 CPSF100_C PF13299.6 CDJ49228.1 - 0.61 10.3 5.6 1 9.6 5.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TERB2 PF15101.6 CDJ49228.1 - 0.97 9.5 9.4 1.3 9.1 9.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Agouti PF05039.12 CDJ49228.1 - 1.1 10.0 7.5 1.9 9.3 7.5 1.3 1 0 0 1 1 1 0 Agouti protein DUF4834 PF16118.5 CDJ49228.1 - 1.6 9.7 10.9 2.9 8.9 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EIIBC-GUT_N PF03612.14 CDJ49228.1 - 2 8.2 7.7 2.9 7.6 7.7 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Roughex PF06020.11 CDJ49228.1 - 2.1 7.3 13.2 2.7 7.0 13.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF3391 PF11871.8 CDJ49228.1 - 3.5 8.2 12.8 3.7 8.1 12.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) CobT PF06213.12 CDJ49228.1 - 3.6 6.9 18.2 5.8 6.2 18.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Shadoo PF14999.6 CDJ49228.1 - 4.2 7.5 8.0 7.1 6.7 8.0 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective eIF-3_zeta PF05091.12 CDJ49228.1 - 5.1 6.0 11.3 6.5 5.6 11.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ORC_WH_C PF18137.1 CDJ49228.1 - 5.4 7.1 10.4 8.2 6.5 10.4 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF3464 PF11947.8 CDJ49228.1 - 6.1 6.6 9.3 9.8 5.9 9.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 XRN_M PF17846.1 CDJ49230.1 - 1.2e-53 182.7 0.4 5.1e-35 121.3 0.1 4.4 4 1 0 4 4 4 2 Xrn1 helical domain TFIIA PF03153.13 CDJ49230.1 - 0.0035 17.4 37.2 0.0035 17.4 37.2 5.7 3 1 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ49230.1 - 0.14 12.0 0.0 0.14 12.0 0.0 4.2 2 2 0 2 2 2 0 SPX domain Utp14 PF04615.13 CDJ49230.1 - 1.6 7.2 0.0 1.6 7.2 0.0 4.1 3 1 2 5 5 5 0 Utp14 protein RskA PF10099.9 CDJ49230.1 - 5.8 7.2 0.0 5.8 7.2 0.0 12.1 2 2 3 6 6 6 0 Anti-sigma-K factor rskA SMK-1 PF04802.15 CDJ49232.1 - 5.2e-10 39.5 0.2 4.4e-06 26.6 0.1 2.8 2 0 0 2 2 2 2 Component of IIS longevity pathway SMK-1 SDA1 PF05285.12 CDJ49232.1 - 0.0023 17.4 35.6 0.0023 17.4 35.6 7.5 5 3 0 6 6 6 1 SDA1 DUF2722 PF10846.8 CDJ49232.1 - 0.003 16.6 3.8 0.003 16.6 3.8 9.6 6 3 3 9 9 9 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ49232.1 - 0.0053 17.1 5.1 0.0053 17.1 5.1 13.4 7 3 4 11 11 11 3 Anti-sigma-K factor rskA Adaptin_binding PF10199.9 CDJ49232.1 - 3 8.4 0.0 3 8.4 0.0 9.2 5 4 0 5 5 5 0 Alpha and gamma adaptin binding protein p34 Baculo_11_kDa PF06143.11 CDJ49233.1 - 0.089 12.4 4.4 0.18 11.4 4.4 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family GBV-C_env PF12786.7 CDJ49233.1 - 0.5 9.0 4.7 0.87 8.2 4.7 1.3 1 0 0 1 1 1 0 GB virus C genotype envelope Apt1 PF10351.9 CDJ49233.1 - 0.59 8.9 26.5 0.32 9.8 4.4 2.4 3 0 0 3 3 3 0 Golgi-body localisation protein domain Sigma_reg_N PF13800.6 CDJ49233.1 - 0.96 9.8 2.2 1.6 9.1 2.2 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Ly49 PF08391.10 CDJ49233.1 - 1.1 9.6 3.1 2.1 8.7 3.1 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF3377 PF11857.8 CDJ49233.1 - 1.8 8.5 7.4 0.36 10.8 3.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) RIFIN PF02009.16 CDJ49234.1 - 0.00086 19.3 18.6 0.001 19.1 18.6 1.1 1 0 0 1 1 1 1 Rifin LRRC37AB_C PF14914.6 CDJ49234.1 - 0.0045 16.9 0.7 0.0063 16.4 0.7 1.2 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain Plasmodium_Vir PF05795.11 CDJ49234.1 - 0.0052 16.3 5.3 0.0061 16.0 5.3 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Orf78 PF06024.12 CDJ49234.1 - 0.099 13.0 7.9 0.33 11.3 7.9 2.1 1 1 0 1 1 1 0 Orf78 (ac78) SPX PF03105.19 CDJ49234.1 - 0.22 11.4 11.5 0.23 11.3 11.5 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ49234.1 - 0.3 9.9 8.1 0.3 9.9 8.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Utp14 PF04615.13 CDJ49234.1 - 0.45 9.0 6.1 0.43 9.1 6.1 1.0 1 0 0 1 1 1 0 Utp14 protein Podoplanin PF05808.11 CDJ49234.1 - 0.55 10.3 14.3 0.55 10.3 12.9 1.7 1 1 1 2 2 2 0 Podoplanin Baculo_11_kDa PF06143.11 CDJ49234.1 - 0.65 9.6 3.4 1.5 8.5 3.4 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family GREB1 PF15782.5 CDJ49234.1 - 0.99 6.4 22.2 1.2 6.2 22.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF572 PF04502.13 CDJ49234.1 - 2.1 7.9 8.0 2.3 7.8 8.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Menin PF05053.13 CDJ49234.1 - 2.3 6.5 20.7 2.8 6.2 20.7 1.1 1 0 0 1 1 1 0 Menin DUF4769 PF15992.5 CDJ49234.1 - 5.5 6.7 5.9 7.2 6.3 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) ETS_PEA3_N PF04621.13 CDJ49234.1 - 9.3 6.0 10.9 12 5.7 10.9 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain CLTH PF10607.9 CDJ49235.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain DUF3446 PF11928.8 CDJ49235.1 - 0.13 12.6 11.3 0.15 12.4 9.6 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain FlxA PF14282.6 CDJ49235.1 - 0.49 10.4 6.2 0.74 9.8 6.2 1.2 1 0 0 1 1 1 0 FlxA-like protein SR-25 PF10500.9 CDJ49235.1 - 0.91 9.1 14.0 1.2 8.7 14.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDP-OH_P_transf PF01066.21 CDJ49236.1 - 5.3e-17 62.3 0.3 5.3e-17 62.3 0.3 2.2 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Ribosomal_60s PF00428.19 CDJ49236.1 - 8.5 7.0 16.7 15 6.3 16.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Metallophos PF00149.28 CDJ49239.1 - 1.3e-22 81.3 0.1 7e-10 39.7 0.6 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase MscS_porin PF12795.7 CDJ49240.1 - 0.00096 18.8 5.8 0.0013 18.3 5.8 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF2353 PF09789.9 CDJ49240.1 - 0.0015 18.0 0.6 0.0016 17.8 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) TolA_bind_tri PF16331.5 CDJ49240.1 - 0.0041 17.2 5.1 0.0063 16.6 5.1 1.2 1 0 0 1 1 1 1 TolA binding protein trimerisation DUF724 PF05266.14 CDJ49240.1 - 0.0049 16.7 1.8 0.0064 16.3 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) HAUS5 PF14817.6 CDJ49240.1 - 0.0093 14.8 1.9 0.011 14.6 1.9 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 Snapin_Pallidin PF14712.6 CDJ49240.1 - 0.013 15.9 0.8 0.017 15.5 0.8 1.2 1 0 0 1 1 1 0 Snapin/Pallidin Prominin PF05478.11 CDJ49240.1 - 0.014 13.4 0.2 0.015 13.3 0.2 1.0 1 0 0 1 1 1 0 Prominin VGPC1_C PF16799.5 CDJ49240.1 - 0.018 15.0 0.8 0.038 14.0 0.8 1.5 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 AAA_23 PF13476.6 CDJ49240.1 - 0.025 15.1 0.6 0.029 14.9 0.6 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 CDJ49240.1 - 0.036 12.9 1.9 0.041 12.8 1.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 CDJ49240.1 - 0.096 13.3 4.2 0.2 12.3 4.2 1.5 1 0 0 1 1 1 0 SlyX NAPRTase_C PF17956.1 CDJ49240.1 - 0.11 13.0 0.2 0.14 12.5 0.2 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain Herpes_U44 PF04533.13 CDJ49240.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.3 1 1 0 1 1 1 0 Herpes virus U44 protein DUF4407 PF14362.6 CDJ49240.1 - 0.17 11.2 2.9 0.19 11.0 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 CDJ49240.1 - 0.22 11.9 5.3 0.28 11.5 5.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) KfrA_N PF11740.8 CDJ49240.1 - 0.56 10.9 11.3 0.3 11.8 9.2 1.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term MerR-DNA-bind PF09278.11 CDJ49240.1 - 0.7 10.5 7.0 0.18 12.4 1.4 2.5 1 1 1 2 2 2 0 MerR, DNA binding DivIC PF04977.15 CDJ49240.1 - 7.1 6.5 9.2 22 4.9 9.1 1.9 1 1 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 CDJ49240.1 - 7.2 7.2 11.5 0.38 11.3 6.4 1.5 2 0 0 2 2 2 0 Apg6 coiled-coil region WD40 PF00400.32 CDJ49242.1 - 2.8e-06 27.9 0.3 2.5 9.1 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1449 PF07290.11 CDJ49244.1 - 0.046 13.3 2.4 0.081 12.5 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) DUF3624 PF12292.8 CDJ49244.1 - 2.9 8.4 9.1 9.4 6.7 6.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) DUF4131 PF13567.6 CDJ49244.1 - 4.4 6.9 5.0 7.5 6.2 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DcuA_DcuB PF03605.14 CDJ49245.1 - 0.0024 16.8 1.2 0.0043 16.0 1.2 1.3 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter DUF1772 PF08592.11 CDJ49245.1 - 0.021 15.2 1.8 2.8 8.3 0.9 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF1700 PF08006.11 CDJ49245.1 - 5.9 6.4 5.8 9.1 5.8 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) TPR_2 PF07719.17 CDJ49246.1 - 0.002 18.1 0.5 0.0094 16.0 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ49246.1 - 0.038 13.8 0.3 0.099 12.5 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ49246.1 - 0.038 14.8 1.7 0.7 10.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ49246.1 - 0.087 13.1 1.8 0.71 10.2 0.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ49246.1 - 0.17 12.2 1.2 0.53 10.6 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ49246.1 - 0.34 11.5 2.5 16 6.1 0.5 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Imm61 PF15598.6 CDJ49247.1 - 0.47 10.3 5.4 1 9.2 3.1 2.9 2 0 0 2 2 2 0 Immunity protein 61 EGF_2 PF07974.13 CDJ49251.1 - 0.59 10.5 41.6 0.09 13.2 7.8 4.2 4 0 0 4 4 4 0 EGF-like domain U-box PF04564.15 CDJ49252.1 - 4e-20 71.8 0.1 1.3e-19 70.2 0.0 1.8 2 0 0 2 2 2 1 U-box domain TPR_1 PF00515.28 CDJ49252.1 - 4.9e-09 35.6 3.0 0.0019 18.0 0.8 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ49252.1 - 1.7e-07 30.8 4.8 0.004 17.2 1.7 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ49252.1 - 0.0014 18.2 1.6 0.06 13.0 0.0 2.4 1 1 1 2 2 2 1 TPR repeat TPR_12 PF13424.6 CDJ49252.1 - 0.0071 16.6 4.5 0.08 13.2 1.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 CDJ49252.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_16 PF13432.6 CDJ49252.1 - 0.044 14.4 4.7 0.046 14.4 1.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat GCP_C_terminal PF04130.13 CDJ49252.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal TPR_8 PF13181.6 CDJ49252.1 - 0.3 11.4 7.3 3 8.3 0.5 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ubiquitin PF00240.23 CDJ49253.1 - 2.6e-34 116.8 0.3 3.6e-34 116.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CDJ49253.1 - 5.9e-30 102.9 11.2 9e-30 102.3 11.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CDJ49253.1 - 6.8e-17 61.1 0.5 1e-16 60.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ49253.1 - 3.3e-06 27.5 0.1 1.2e-05 25.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ49253.1 - 0.004 17.1 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ49253.1 - 0.011 16.1 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ49253.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDJ49253.1 - 0.025 14.6 0.8 5.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CDJ49253.1 - 0.044 14.4 0.0 0.053 14.1 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Surface_antigen PF11054.8 CDJ49254.1 - 2.2e-26 93.1 2.7 5.9e-26 91.6 2.7 1.6 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Pkinase PF00069.25 CDJ49255.1 - 4.6e-31 108.2 5.6 1.8e-22 80.0 0.0 3.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ49255.1 - 4.7e-22 78.5 1.1 2.7e-16 59.6 0.0 2.9 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CDJ49255.1 - 4.7e-05 22.8 0.1 4.7e-05 22.8 0.1 2.2 1 1 1 2 2 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SUIM_assoc PF16619.5 CDJ49255.1 - 0.0023 18.0 2.3 0.0023 18.0 2.3 5.3 2 1 1 3 3 1 1 Unstructured region C-term to UIM in Ataxin3 MMR1 PF08505.10 CDJ49255.1 - 0.019 15.3 16.9 0.022 15.0 16.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein APH PF01636.23 CDJ49255.1 - 0.021 14.7 0.0 0.021 14.7 0.0 2.2 1 1 1 2 2 1 0 Phosphotransferase enzyme family TFIIA PF03153.13 CDJ49255.1 - 0.03 14.3 46.3 0.039 13.9 46.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ49255.1 - 0.043 13.4 20.2 0.05 13.2 20.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit RR_TM4-6 PF06459.12 CDJ49255.1 - 0.94 9.3 15.8 1.6 8.5 15.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.6 CDJ49255.1 - 1.3 7.3 2.6 1.4 7.2 2.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 CDJ49255.1 - 3.2 6.4 19.1 4.3 6.0 19.1 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ49255.1 - 5.4 5.9 20.1 7.1 5.5 20.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SUIM_assoc PF16619.5 CDJ49257.1 - 1.2e-05 25.2 0.0 1.2e-05 25.2 0.0 18.0 9 5 5 14 14 14 1 Unstructured region C-term to UIM in Ataxin3 Phostensin_N PF13916.6 CDJ49257.1 - 0.011 16.1 2.4 0.011 16.1 2.4 12.6 11 4 0 11 11 11 0 PP1-regulatory protein, Phostensin N-terminal MRP-S27 PF10037.9 CDJ49258.1 - 3.9 6.3 25.7 0.23 10.3 17.9 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 APC1_C PF18122.1 CDJ49258.1 - 4.4 7.2 9.0 17 5.3 9.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain SUIM_assoc PF16619.5 CDJ49259.1 - 0.0049 16.9 0.0 0.0049 16.9 0.0 7.4 6 2 0 6 6 6 2 Unstructured region C-term to UIM in Ataxin3 HAUS6_N PF14661.6 CDJ49259.1 - 9 5.8 21.1 6.6 6.2 11.6 2.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus SUIM_assoc PF16619.5 CDJ49260.1 - 0.27 11.3 0.0 0.27 11.3 0.0 7.2 5 2 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 CDJ49261.1 - 8e-05 22.6 0.1 8e-05 22.6 0.1 27.1 7 3 1 8 8 8 2 Unstructured region C-term to UIM in Ataxin3 Helicase_C_2 PF13307.6 CDJ49262.1 - 1.5e-40 139.2 0.0 1.5e-40 139.2 0.0 3.2 3 2 1 4 4 4 1 Helicase C-terminal domain HBB PF06777.11 CDJ49262.1 - 5.1e-20 72.0 9.8 3.3e-13 49.7 0.0 3.6 2 1 1 3 3 3 2 Helical and beta-bridge domain DEAD_2 PF06733.15 CDJ49262.1 - 4.4e-19 68.8 20.8 2.7e-11 43.4 0.0 4.5 5 0 0 5 5 5 3 DEAD_2 ResIII PF04851.15 CDJ49262.1 - 0.00042 20.4 0.5 0.00042 20.4 0.5 3.9 3 1 1 4 4 4 2 Type III restriction enzyme, res subunit DUF4647 PF15504.6 CDJ49262.1 - 0.0026 17.0 2.1 0.0026 17.0 2.1 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4647) DUF2722 PF10846.8 CDJ49262.1 - 0.29 10.0 65.0 0.19 10.6 10.2 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) PRMT5 PF05185.16 CDJ49263.1 - 6.1e-43 146.7 0.2 1.8e-29 102.8 0.0 2.8 2 0 0 2 2 2 2 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CDJ49263.1 - 2.9e-26 92.4 0.0 1.6e-25 90.0 0.0 2.3 1 1 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 CDJ49263.1 - 1.3e-21 76.9 2.0 4.3e-17 62.2 0.2 3.8 2 0 0 2 2 2 2 PRMT5 TIM barrel domain RskA PF10099.9 CDJ49263.1 - 0.023 15.0 0.0 0.023 15.0 0.0 26.5 8 6 14 24 24 24 0 Anti-sigma-K factor rskA Use1 PF09753.9 CDJ49264.1 - 0.03 14.0 0.0 0.046 13.4 0.0 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 bZIP_1 PF00170.21 CDJ49264.1 - 0.14 12.2 2.2 0.69 10.0 2.2 2.0 1 1 0 1 1 1 0 bZIP transcription factor RskA PF10099.9 CDJ49265.1 - 0.0057 17.0 3.7 0.0064 16.8 3.7 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DnaJ_C PF01556.18 CDJ49267.1 - 8.8e-25 87.5 0.0 1.8e-24 86.5 0.0 1.5 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CDJ49267.1 - 1.1e-06 28.9 19.2 2e-06 28.1 19.2 1.4 1 0 0 1 1 1 1 DnaJ central domain PHD_4 PF16866.5 CDJ49267.1 - 0.0078 16.3 0.4 0.023 14.8 0.4 1.7 1 0 0 1 1 1 1 PHD-finger RRF PF01765.19 CDJ49270.1 - 3.4e-32 111.6 4.5 6.6e-32 110.7 4.5 1.4 1 0 0 1 1 1 1 Ribosome recycling factor DUF2113 PF09886.9 CDJ49270.1 - 0.0019 17.6 0.1 0.0033 16.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2113) SpoIIIAH PF12685.7 CDJ49270.1 - 1.3 8.8 7.9 2.5 7.9 7.8 1.4 1 1 0 1 1 1 0 SpoIIIAH-like protein CSN5_C PF18323.1 CDJ49270.1 - 3.5 8.6 10.4 1.5 9.8 1.2 2.7 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain HK97-gp10_like PF04883.12 CDJ49270.1 - 3.9 8.5 7.2 2.5 9.1 0.5 3.4 3 1 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component CKS PF01111.19 CDJ49272.1 - 1.3e-20 73.4 0.0 2.6e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit TLP-20 PF06088.11 CDJ49272.1 - 0.0016 18.4 0.3 0.065 13.1 0.0 2.3 2 0 0 2 2 2 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Peptidase_M20 PF01546.28 CDJ49273.1 - 2.7e-17 63.2 0.1 5.1e-07 29.6 0.0 3.5 3 0 0 3 3 3 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDJ49273.1 - 2.1e-07 30.8 0.0 4.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 CDJ49273.1 - 7.6e-07 29.7 12.7 0.28 12.1 1.6 6.1 5 1 0 5 5 5 3 WD domain, G-beta repeat GATase_6 PF13522.6 CDJ49273.1 - 9.6e-05 22.6 0.0 0.00043 20.5 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain Topoisom_I PF01028.20 CDJ49276.1 - 3.2e-14 52.7 0.1 4.8e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core DUF3138 PF11336.8 CDJ49276.1 - 0.0021 16.8 3.4 0.0024 16.6 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) NAM-associated PF14303.6 CDJ49276.1 - 0.0093 16.7 6.0 0.011 16.4 6.0 1.1 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain DUF3246 PF11596.8 CDJ49276.1 - 0.089 12.2 0.8 0.1 12.0 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF4407 PF14362.6 CDJ49276.1 - 0.12 11.7 9.1 0.16 11.3 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2057 PF09829.9 CDJ49276.1 - 0.2 11.8 4.6 0.36 11.0 4.6 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) PPP4R2 PF09184.11 CDJ49276.1 - 0.33 10.5 5.6 0.42 10.1 5.6 1.1 1 0 0 1 1 1 0 PPP4R2 AC_N PF16214.5 CDJ49276.1 - 0.38 9.8 1.2 0.44 9.6 1.2 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region THOC2_N PF16134.5 CDJ49276.1 - 0.76 8.3 7.2 1.1 7.9 7.2 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Topoisom_I_N PF02919.15 CDJ49277.1 - 3.9e-48 163.8 0.0 5.1e-31 107.9 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF4298 PF14131.6 CDJ49277.1 - 0.15 12.0 0.5 8.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Period_C PF12114.8 CDJ49277.1 - 4 7.0 8.7 6.8 6.2 8.7 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region AF-4 PF05110.13 CDJ49277.1 - 6.6 4.7 16.1 8.5 4.3 16.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3395 PF11875.8 CDJ49278.1 - 3.1e-18 66.2 0.0 3.1e-18 66.2 0.0 3.6 2 2 1 3 3 3 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CDJ49278.1 - 7.9e-15 54.7 0.5 2e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain DUF4145 PF13643.6 CDJ49278.1 - 0.029 14.5 0.0 0.071 13.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4145) Macoilin PF09726.9 CDJ49278.1 - 0.051 12.1 21.8 0.066 11.8 21.8 1.1 1 0 0 1 1 1 0 Macoilin family RSRP PF17069.5 CDJ49278.1 - 0.37 10.3 25.5 0.65 9.5 25.5 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Mu-like_Pro PF10123.9 CDJ49278.1 - 0.38 10.3 7.9 0.88 9.1 8.0 1.6 1 1 0 1 1 1 0 Mu-like prophage I protein AF-4 PF05110.13 CDJ49278.1 - 0.58 8.2 30.2 0.72 7.9 30.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_S64 PF08192.11 CDJ49278.1 - 2.8 6.3 20.0 4.2 5.8 20.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 DOCK_N PF16172.5 CDJ49278.1 - 3.3 6.5 13.9 1.7 7.4 11.5 1.6 1 1 0 1 1 1 0 DOCK N-terminus SID-1_RNA_chan PF13965.6 CDJ49278.1 - 8.3 4.7 6.7 13 4.0 6.7 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AAA PF00004.29 CDJ49279.1 - 2.9e-30 105.4 0.1 2.9e-30 105.4 0.1 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CDJ49279.1 - 0.00072 19.7 0.0 0.00072 19.7 0.0 3.2 2 2 2 4 4 4 1 AAA domain (Cdc48 subfamily) GHMP_kinases_N PF00288.26 CDJ49279.1 - 3 8.1 0.0 3 8.1 0.0 3.9 3 1 1 4 4 4 0 GHMP kinases N terminal domain NUDIX PF00293.28 CDJ49280.1 - 0.00033 20.7 0.1 0.022 14.8 0.0 2.3 2 0 0 2 2 2 1 NUDIX domain EPL1 PF10513.9 CDJ49280.1 - 0.08 13.3 11.8 1.1 9.7 1.9 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Apt1 PF10351.9 CDJ49280.1 - 1.2 8.0 17.8 0.075 11.9 9.8 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ctr PF04145.15 CDJ49280.1 - 3.2 8.3 10.5 15 6.2 0.6 2.5 2 0 0 2 2 2 0 Ctr copper transporter family Presenilin PF01080.17 CDJ49280.1 - 5.1 5.8 24.5 2.5 6.8 11.0 2.1 2 0 0 2 2 2 0 Presenilin AroM PF07302.11 CDJ49281.1 - 0.02 14.3 7.9 0.029 13.7 7.7 1.6 1 1 0 1 1 1 0 AroM protein NINJA_B PF16136.5 CDJ49281.1 - 0.026 14.9 5.3 0.034 14.5 5.3 1.1 1 0 0 1 1 1 0 Putative nuclear localisation signal DUF677 PF05055.12 CDJ49281.1 - 0.23 10.3 1.4 0.25 10.2 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) RskA PF10099.9 CDJ49281.1 - 0.46 10.7 23.4 0.58 10.4 23.4 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Sec34 PF04136.15 CDJ49281.1 - 1 9.2 5.0 0.35 10.8 1.3 1.8 2 0 0 2 2 2 0 Sec34-like family RIFIN PF02009.16 CDJ49281.1 - 1.9 8.3 6.3 2.4 8.0 6.3 1.1 1 0 0 1 1 1 0 Rifin DUF3886 PF13025.6 CDJ49281.1 - 3.6 7.8 8.1 0.21 11.8 1.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3886) MASE2 PF05230.11 CDJ49282.1 - 0.034 14.2 0.3 0.034 14.2 0.3 3.0 2 0 0 2 2 2 0 MASE2 domain CDC45 PF02724.14 CDJ49283.1 - 3.7e-05 22.3 23.8 3.7e-05 22.3 23.8 1.7 2 0 0 2 2 2 1 CDC45-like protein Presenilin PF01080.17 CDJ49283.1 - 0.00017 20.5 34.3 0.00017 20.5 34.3 2.1 2 0 0 2 2 2 1 Presenilin Trypan_PARP PF05887.11 CDJ49283.1 - 0.003 17.5 2.2 0.003 17.5 2.2 1.9 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) Ribosomal_60s PF00428.19 CDJ49283.1 - 0.0069 16.9 4.0 0.0069 16.9 4.0 2.7 2 1 0 2 2 2 1 60s Acidic ribosomal protein Orf78 PF06024.12 CDJ49283.1 - 0.023 15.0 2.2 0.023 15.0 2.2 4.1 2 1 1 3 3 2 0 Orf78 (ac78) Hamartin PF04388.12 CDJ49283.1 - 0.14 10.8 39.4 0.17 10.6 39.4 1.0 1 0 0 1 1 1 0 Hamartin protein FAM60A PF15396.6 CDJ49283.1 - 0.35 10.8 32.3 0.097 12.7 26.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A TMEM144 PF07857.12 CDJ49283.1 - 0.35 9.8 5.7 4.6 6.1 1.8 2.3 1 1 1 2 2 2 0 Transmembrane family, TMEM144 of transporters DUF3899 PF13038.6 CDJ49283.1 - 1.2 9.7 0.0 1.2 9.7 0.0 2.8 2 1 1 3 3 1 0 Domain of unknown function (DUF3899) ASFV_J13L PF05568.11 CDJ49283.1 - 2.6 7.8 10.3 0.63 9.8 7.1 1.7 1 1 0 1 1 1 0 African swine fever virus J13L protein DUF819 PF05684.12 CDJ49283.1 - 5.6 5.9 6.4 1.5 7.8 0.8 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF819) NPR3 PF03666.13 CDJ49283.1 - 6.3 5.5 36.2 1.4 7.6 31.3 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Thioredoxin PF00085.20 CDJ49284.1 - 1.7e-35 121.1 6.0 3.2e-21 75.3 0.0 3.4 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 CDJ49284.1 - 6.1e-05 23.1 4.4 0.022 14.9 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CDJ49284.1 - 0.00014 22.1 2.1 0.12 12.7 0.0 3.7 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 CDJ49284.1 - 0.0044 16.9 0.8 0.063 13.2 0.0 2.8 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CDJ49284.1 - 0.011 16.1 6.3 0.63 10.5 0.2 3.5 3 1 0 3 3 2 0 Thioredoxin-like domain Herpes_HEPA PF03324.14 CDJ49284.1 - 0.021 15.3 0.1 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus DNA helicase/primase complex associated protein DUF5336 PF17270.2 CDJ49284.1 - 0.029 14.0 5.4 0.068 12.8 5.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Thioredoxin_3 PF13192.6 CDJ49284.1 - 0.042 13.9 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin domain OST3_OST6 PF04756.13 CDJ49284.1 - 0.093 12.1 0.0 5.4 6.3 0.0 2.9 3 1 0 3 3 3 0 OST3 / OST6 family, transporter family Med15 PF09606.10 CDJ49284.1 - 0.14 10.8 11.6 0.2 10.3 11.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RcpC PF16976.5 CDJ49284.1 - 0.26 11.3 3.8 0.6 10.2 3.8 1.6 1 0 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB Pex14_N PF04695.13 CDJ49284.1 - 0.37 11.4 10.8 0.4 11.3 5.9 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ49284.1 - 0.41 10.6 13.9 0.068 13.2 10.5 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CDK2AP PF09806.9 CDJ49284.1 - 1.1 9.3 9.2 0.99 9.4 0.6 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein IMUP PF15761.5 CDJ49284.1 - 1.3 9.8 16.6 0.55 10.9 12.7 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ49284.1 - 1.4 8.5 21.8 0.43 10.2 13.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Thioredoxin_9 PF14595.6 CDJ49284.1 - 1.6 8.5 8.1 1.8 8.4 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin DUF4834 PF16118.5 CDJ49284.1 - 4.2 8.4 10.3 48 5.0 8.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Pex26 PF07163.12 CDJ49284.1 - 4.3 6.5 9.7 5.7 6.2 2.8 2.3 2 0 0 2 2 2 0 Pex26 protein Roughex PF06020.11 CDJ49284.1 - 6.6 5.7 7.7 0.29 10.2 2.2 1.4 2 0 0 2 2 2 0 Drosophila roughex protein DUF908 PF06012.12 CDJ49286.1 - 2.2e-09 37.2 20.5 4.2e-08 33.0 0.2 2.1 2 0 0 2 2 2 2 Domain of Unknown Function (DUF908) SR-25 PF10500.9 CDJ49286.1 - 4.5e-05 23.2 11.1 4.5e-05 23.2 11.1 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein MMR1 PF08505.10 CDJ49286.1 - 0.0049 17.2 13.5 0.0049 17.2 13.5 2.3 2 1 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein Rrn6 PF10214.9 CDJ49286.1 - 0.0088 14.6 20.3 0.011 14.2 20.3 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF913 PF06025.12 CDJ49286.1 - 0.0089 15.0 5.6 0.05 12.6 5.0 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF2828 PF11443.8 CDJ49286.1 - 0.01 13.9 8.8 0.014 13.5 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NPR3 PF03666.13 CDJ49286.1 - 0.013 14.3 10.1 0.021 13.6 10.1 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Raftlin PF15250.6 CDJ49286.1 - 0.015 14.1 10.4 0.023 13.5 10.4 1.3 1 0 0 1 1 1 0 Raftlin DUF4551 PF15087.6 CDJ49286.1 - 0.019 13.8 13.4 0.035 12.9 13.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.7 CDJ49286.1 - 0.02 13.0 13.5 0.029 12.5 13.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PIP5K PF01504.18 CDJ49286.1 - 0.022 14.0 6.8 0.044 13.0 6.8 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase V_ATPase_I PF01496.19 CDJ49286.1 - 0.037 11.9 8.6 0.057 11.3 8.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SAGA-Tad1 PF12767.7 CDJ49286.1 - 0.047 13.4 12.3 0.053 13.2 11.3 1.6 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Suf PF05843.14 CDJ49286.1 - 0.089 12.8 22.0 0.17 11.8 22.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ49286.1 - 0.27 10.0 20.8 0.49 9.1 20.8 1.4 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 CDJ49286.1 - 0.44 8.4 32.3 0.66 7.8 32.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ndc1_Nup PF09531.10 CDJ49286.1 - 0.58 8.8 19.8 0.044 12.5 14.2 1.8 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 CDJ49286.1 - 0.95 9.5 10.7 2.1 8.3 10.7 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ49286.1 - 1.4 7.6 9.2 2.1 7.1 9.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ49286.1 - 1.5 7.8 15.4 2.1 7.3 15.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 EOS1 PF12326.8 CDJ49286.1 - 1.5 8.7 12.5 0.16 11.9 0.1 2.3 1 1 1 2 2 2 0 N-glycosylation protein SARAF PF06682.12 CDJ49286.1 - 2 8.0 18.7 0.71 9.5 15.0 1.9 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Orf78 PF06024.12 CDJ49286.1 - 2.1 8.7 9.2 12 6.2 4.1 2.5 2 0 0 2 2 2 0 Orf78 (ac78) Apt1 PF10351.9 CDJ49286.1 - 3.2 6.5 13.7 1.9 7.2 10.2 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain SMYLE_N PF18615.1 CDJ49286.1 - 3.3 7.2 16.6 0.12 11.9 9.7 1.8 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF3499 PF12005.8 CDJ49286.1 - 3.6 8.2 11.6 1.1 9.9 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) CAF1 PF04857.20 CDJ49286.1 - 3.9 6.5 9.5 7.1 5.7 9.5 1.4 1 0 0 1 1 1 0 CAF1 family ribonuclease RNase_H2_suC PF08615.11 CDJ49286.1 - 4.8 7.3 12.7 47 4.1 12.7 2.4 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM60A PF15396.6 CDJ49286.1 - 5.1 7.1 21.5 0.46 10.5 16.6 1.6 2 0 0 2 2 2 0 Protein Family FAM60A SKA1 PF07160.12 CDJ49286.1 - 5.3 6.8 16.9 10 5.9 16.9 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Mlh1_C PF16413.5 CDJ49286.1 - 10 5.4 19.5 0.69 9.2 6.8 2.3 1 1 1 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus CENP-H PF05837.12 CDJ49287.1 - 0.021 15.3 3.3 0.027 14.9 3.3 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3744 PF12558.8 CDJ49287.1 - 0.06 14.1 0.6 0.12 13.1 0.6 1.7 1 1 0 1 1 1 0 ATP-binding cassette cobalt transporter PH_TFIIH PF08567.11 CDJ49287.1 - 0.073 13.4 0.3 0.091 13.1 0.3 1.1 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain JHD PF17811.1 CDJ49287.1 - 0.084 13.4 0.8 0.11 13.1 0.7 1.3 1 1 0 1 1 1 0 Jumonji helical domain TMF_TATA_bd PF12325.8 CDJ49287.1 - 0.13 12.5 4.9 0.17 12.1 4.9 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Ephrin_rec_like PF07699.13 CDJ49289.1 - 0.68 9.8 12.2 7.5 6.4 0.5 3.2 2 0 0 2 2 2 0 Putative ephrin-receptor like SGL PF08450.12 CDJ49290.1 - 1.1e-09 38.3 0.0 6.6e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 CDJ49290.1 - 3.2e-09 36.4 0.2 0.0011 18.9 0.0 5.0 4 0 0 4 4 4 3 NHL repeat Ephrin_rec_like PF07699.13 CDJ49290.1 - 0.003 17.3 1.5 0.003 17.3 1.5 29.1 20 7 10 31 31 31 13 Putative ephrin-receptor like Lactonase PF10282.9 CDJ49290.1 - 0.0041 16.4 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Glyco_hydro_8 PF01270.17 CDJ49290.1 - 0.23 10.2 0.0 0.4 9.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 DDHD PF02862.17 CDJ49291.1 - 0.19 11.8 7.7 0.18 11.9 5.8 1.7 2 0 0 2 2 2 0 DDHD domain Baculo_PP31 PF05311.11 CDJ49291.1 - 0.2 11.1 9.9 0.31 10.5 9.9 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) TERB2 PF15101.6 CDJ49291.1 - 0.93 9.5 15.1 1.9 8.5 15.1 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 eIF-3_zeta PF05091.12 CDJ49291.1 - 2 7.3 19.9 2.8 6.8 19.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S49_N PF08496.10 CDJ49291.1 - 5.2 7.1 11.3 9.9 6.2 11.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PIG-S PF10510.9 CDJ49291.1 - 6.8 5.4 15.5 9.8 4.9 15.5 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein UPF0560 PF10577.9 CDJ49291.1 - 7.1 5.0 18.9 11 4.4 18.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 LAM_C PF12544.8 CDJ49291.1 - 7.8 6.7 6.9 1.3e+02 2.7 6.5 2.2 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Spt20 PF12090.8 CDJ49291.1 - 9 5.8 41.7 0.32 10.6 35.1 1.8 2 0 0 2 2 2 0 Spt20 family RskA PF10099.9 CDJ49292.1 - 0.00036 20.9 15.9 0.00036 20.9 15.9 5.9 2 2 3 5 5 5 1 Anti-sigma-K factor rskA ANAPC3 PF12895.7 CDJ49292.1 - 0.0037 17.4 2.6 0.0037 17.4 2.6 7.8 6 2 2 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CDJ49292.1 - 0.0042 17.6 2.3 0.0042 17.6 2.3 8.1 7 1 2 9 9 9 3 Tetratricopeptide repeat DUF4667 PF15700.5 CDJ49292.1 - 0.016 15.4 0.1 0.016 15.4 0.1 5.5 5 1 0 5 5 5 0 Domain of unknown function (DUF4667) TPR_8 PF13181.6 CDJ49292.1 - 5.2 7.6 12.9 0.96 9.8 0.4 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SR-25 PF10500.9 CDJ49293.1 - 0.0049 16.5 28.3 0.0049 16.5 28.3 2.2 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein eIF_4EBP PF05456.11 CDJ49293.1 - 0.55 10.2 18.4 0.089 12.7 4.3 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) RskA PF10099.9 CDJ49293.1 - 0.96 9.7 55.6 0.047 14.0 24.6 3.4 1 1 2 3 3 2 0 Anti-sigma-K factor rskA SPX PF03105.19 CDJ49293.1 - 0.96 9.3 21.8 1.2 8.9 21.8 1.3 1 0 0 1 1 1 0 SPX domain EFTUD2 PF16004.5 CDJ49293.1 - 1.3 9.6 27.1 1.4 9.5 11.6 2.5 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Apc15p PF05841.11 CDJ49293.1 - 2.2 9.1 42.5 0.22 12.3 19.0 3.1 2 2 0 2 2 2 0 Apc15p protein Peptidase_S64 PF08192.11 CDJ49293.1 - 2.7 6.4 26.8 3.5 6.0 26.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF4614 PF15391.6 CDJ49293.1 - 4.4 7.3 37.6 0.27 11.2 19.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) U1snRNP70_N PF12220.8 CDJ49293.1 - 6.6 7.5 22.2 2.4 8.8 4.3 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pinin_SDK_memA PF04696.13 CDJ49293.1 - 6.8 6.8 37.8 4.9 7.2 15.9 2.5 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Spt20 PF12090.8 CDJ49293.1 - 8.5 5.9 74.6 0.03 13.9 21.6 2.7 2 1 1 3 3 3 0 Spt20 family GTP_EFTU PF00009.27 CDJ49294.1 - 4.3e-16 59.0 0.0 3.2e-15 56.2 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ49294.1 - 3e-09 37.0 0.1 2.8e-07 30.6 0.0 2.4 1 1 1 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 CDJ49294.1 - 1.4e-05 25.3 0.0 0.074 13.3 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ49294.1 - 0.00036 20.0 0.3 0.75 9.2 0.1 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Arf PF00025.21 CDJ49294.1 - 0.001 18.6 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.18 CDJ49294.1 - 0.0032 17.0 0.0 0.33 10.5 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF4420 PF14390.6 CDJ49294.1 - 0.0061 15.8 0.9 0.2 10.9 0.0 2.2 2 0 0 2 2 2 1 Putative PD-(D/E)XK family member, (DUF4420) Dynamin_N PF00350.23 CDJ49294.1 - 0.0067 16.5 0.1 0.0067 16.5 0.1 2.0 2 1 0 2 2 2 1 Dynamin family Ras PF00071.22 CDJ49294.1 - 0.0087 15.7 0.0 0.053 13.1 0.0 2.1 2 0 0 2 2 2 1 Ras family RskA PF10099.9 CDJ49294.1 - 0.032 14.6 1.4 0.032 14.6 1.4 3.4 2 1 1 3 3 2 0 Anti-sigma-K factor rskA G-alpha PF00503.20 CDJ49294.1 - 0.032 13.4 6.2 0.68 9.0 2.4 2.3 2 1 0 2 2 2 0 G-protein alpha subunit TniB PF05621.11 CDJ49294.1 - 0.053 12.9 0.4 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein SPX PF03105.19 CDJ49294.1 - 0.17 11.8 24.6 0.041 13.8 20.1 1.9 1 1 1 2 2 2 0 SPX domain Nrap_D5 PF17406.2 CDJ49294.1 - 0.29 10.9 2.3 0.43 10.3 0.5 2.0 2 0 0 2 2 2 0 Nrap protein PAP/OAS1-like domain 5 Glyco_hydro_3_C PF01915.22 CDJ49294.1 - 0.98 9.3 9.4 0.32 10.9 6.1 2.0 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain ACC_epsilon PF13822.6 CDJ49295.1 - 0.02 15.6 1.4 0.02 15.6 1.4 3.0 2 1 1 3 3 3 0 Acyl-CoA carboxylase epsilon subunit RskA PF10099.9 CDJ49295.1 - 1.1 9.5 20.7 2.8 8.2 20.7 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ49295.1 - 8.3 5.9 10.9 2.9 7.4 8.1 1.6 2 0 0 2 2 2 0 Spt20 family RMI1_N PF08585.12 CDJ49296.1 - 7.6e-20 71.6 13.2 7.5e-14 52.0 0.0 4.2 3 1 2 5 5 5 2 RecQ mediated genome instability protein SR-25 PF10500.9 CDJ49296.1 - 6.9e-05 22.6 8.9 6.9e-05 22.6 8.9 2.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ49296.1 - 0.012 14.5 0.6 0.023 13.6 0.6 1.4 1 1 0 1 1 1 0 Golgi-body localisation protein domain BRCA-2_OB1 PF09103.10 CDJ49296.1 - 0.079 12.9 0.0 0.45 10.5 0.0 2.1 2 1 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 DUF4614 PF15391.6 CDJ49296.1 - 1.3 9.0 17.1 2.1 8.3 11.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) CCSAP PF15748.5 CDJ49296.1 - 1.9 8.6 14.9 0.027 14.7 2.8 2.9 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated IMS PF00817.20 CDJ49297.1 - 1.7e-07 31.3 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family DUF4667 PF15700.5 CDJ49297.1 - 0.0033 17.6 0.9 0.0033 17.6 0.9 4.1 3 1 1 4 4 4 2 Domain of unknown function (DUF4667) Mlh1_C PF16413.5 CDJ49297.1 - 0.22 10.9 5.0 0.61 9.4 5.0 1.7 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus TFB6 PF17110.5 CDJ49297.1 - 0.63 9.8 4.0 1.1 8.9 4.0 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RICTOR_N PF14664.6 CDJ49297.1 - 0.77 8.7 4.6 1.9 7.4 4.6 1.6 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF4746 PF15928.5 CDJ49297.1 - 1.5 8.1 7.7 2.7 7.3 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) EPL1 PF10513.9 CDJ49297.1 - 1.9 8.9 17.3 0.21 12.0 8.0 3.0 3 0 0 3 3 3 0 Enhancer of polycomb-like Mitofilin PF09731.9 CDJ49297.1 - 3.3 6.4 29.5 1.1 8.0 17.2 2.3 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Hid1 PF12722.7 CDJ49299.1 - 0.12 10.4 10.6 0.13 10.4 10.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 CDJ49299.1 - 1.5 7.8 12.8 1.5 7.8 12.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Grg1 PF11034.8 CDJ49299.1 - 7.7 6.8 34.2 4.1 7.7 6.2 4.4 1 1 2 3 3 3 0 Glucose-repressible protein Grg1 Spt20 PF12090.8 CDJ49302.1 - 0.0014 18.3 24.2 0.002 17.8 24.2 1.1 1 0 0 1 1 1 1 Spt20 family PCI PF01399.27 CDJ49302.1 - 0.0025 18.3 2.7 0.058 13.9 0.0 2.6 3 0 0 3 3 2 1 PCI domain RskA PF10099.9 CDJ49302.1 - 0.0046 17.3 26.7 0.0046 17.3 26.7 2.4 1 1 1 2 2 1 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ49302.1 - 0.022 15.7 10.7 0.035 15.0 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pex26 PF07163.12 CDJ49302.1 - 0.026 13.9 7.7 0.043 13.1 7.7 1.3 1 0 0 1 1 1 0 Pex26 protein TERB2 PF15101.6 CDJ49302.1 - 0.037 14.1 13.9 0.056 13.5 13.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 CDJ49302.1 - 0.038 12.8 6.4 0.052 12.3 6.4 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 CDJ49302.1 - 0.074 13.2 5.9 0.12 12.5 5.9 1.3 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 CDJ49302.1 - 0.084 12.9 0.2 0.083 12.9 0.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 CDJ49302.1 - 0.096 12.6 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF2828 PF11443.8 CDJ49302.1 - 0.25 9.4 4.6 0.33 9.0 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TMEM51 PF15345.6 CDJ49302.1 - 0.25 11.2 7.6 0.42 10.4 7.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 G0-G1_switch_2 PF15103.6 CDJ49302.1 - 0.29 11.6 4.5 0.49 10.8 4.5 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF2214 PF09980.9 CDJ49302.1 - 0.37 10.6 1.5 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2214) CPSF100_C PF13299.6 CDJ49302.1 - 0.39 10.9 7.0 0.21 11.8 4.6 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CNDH2_M PF16869.5 CDJ49302.1 - 0.53 11.0 7.9 1.1 9.9 7.9 1.5 1 0 0 1 1 1 0 PF16858 UPF0565 PF10561.9 CDJ49302.1 - 0.54 9.4 3.8 7.3 5.7 4.9 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 TFIIA PF03153.13 CDJ49302.1 - 1.1 9.2 30.8 2 8.4 30.9 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 CDJ49302.1 - 1.2 7.9 7.6 1.6 7.5 7.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1003 PF06210.11 CDJ49302.1 - 1.4 9.1 7.0 2.3 8.4 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) eIF-3_zeta PF05091.12 CDJ49302.1 - 1.8 7.5 13.6 2.3 7.1 13.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GREB1 PF15782.5 CDJ49302.1 - 2.3 5.3 8.8 3 4.9 8.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Band_3_cyto PF07565.13 CDJ49302.1 - 2.8 7.7 8.9 4 7.2 8.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain V_ATPase_I PF01496.19 CDJ49302.1 - 3.4 5.5 8.9 4.4 5.1 8.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ctr PF04145.15 CDJ49302.1 - 3.6 8.2 6.2 6.6 7.3 6.2 1.4 1 0 0 1 1 1 0 Ctr copper transporter family CLN3 PF02487.17 CDJ49302.1 - 3.8 6.5 6.5 6.8 5.6 6.5 1.3 1 0 0 1 1 1 0 CLN3 protein Roughex PF06020.11 CDJ49302.1 - 4.4 6.3 12.1 7.7 5.5 12.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF4228 PF14009.6 CDJ49302.1 - 4.6 7.6 9.3 3.4 8.0 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) UPF0560 PF10577.9 CDJ49302.1 - 5.9 5.3 15.4 7.7 4.9 15.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF702 PF05142.12 CDJ49302.1 - 5.9 7.4 13.6 10 6.6 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) SpoIIP PF07454.11 CDJ49302.1 - 7.7 5.9 12.2 11 5.4 12.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) BRF1 PF07741.13 CDJ49302.1 - 9 6.7 12.1 21 5.5 12.1 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain tRNA-synt_2d PF01409.20 CDJ49303.1 - 2.1e-47 161.7 0.4 4.8e-33 114.7 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 CDJ49303.1 - 0.028 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain Pkinase PF00069.25 CDJ49305.1 - 1.1e-12 48.0 0.0 1.1e-12 48.0 0.0 5.3 3 2 1 4 4 4 2 Protein kinase domain Pkinase_fungal PF17667.1 CDJ49305.1 - 9.1 4.9 0.0 9.1 4.9 0.0 4.0 2 1 1 3 3 3 0 Fungal protein kinase DUF4366 PF14283.6 CDJ49306.1 - 0.0057 16.7 1.5 0.0062 16.6 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Pex14_N PF04695.13 CDJ49306.1 - 0.074 13.7 13.0 0.08 13.6 13.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pex26 PF07163.12 CDJ49306.1 - 0.19 11.0 11.9 0.2 10.9 11.9 1.0 1 0 0 1 1 1 0 Pex26 protein Kei1 PF08552.11 CDJ49306.1 - 0.24 11.3 3.6 0.28 11.0 3.6 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 PBP1_TM PF14812.6 CDJ49306.1 - 0.31 11.4 3.7 0.54 10.7 3.7 1.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.22 CDJ49306.1 - 0.51 9.5 3.4 0.62 9.2 3.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Scs3p PF10261.9 CDJ49306.1 - 0.54 9.7 3.5 0.59 9.6 3.5 1.0 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM HCO3_cotransp PF00955.21 CDJ49306.1 - 0.55 9.0 3.1 0.63 8.8 3.1 1.0 1 0 0 1 1 1 0 HCO3- transporter family Connexin PF00029.19 CDJ49306.1 - 0.69 9.6 7.4 0.79 9.4 7.4 1.1 1 0 0 1 1 1 0 Connexin VIT1 PF01988.19 CDJ49306.1 - 0.89 9.4 7.9 0.92 9.3 7.9 1.1 1 0 0 1 1 1 0 VIT family RCR PF12273.8 CDJ49306.1 - 1.4 9.6 8.9 1.9 9.2 8.9 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Sec62 PF03839.16 CDJ49306.1 - 2.8 7.4 8.4 3.1 7.2 8.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CLN3 PF02487.17 CDJ49306.1 - 3.1 6.7 8.1 3.2 6.7 8.1 1.0 1 0 0 1 1 1 0 CLN3 protein SpoVR PF04293.13 CDJ49306.1 - 3.9 6.1 10.5 4.2 6.0 10.5 1.0 1 0 0 1 1 1 0 SpoVR like protein DUF1963 PF09234.10 CDJ49306.1 - 4.1 7.8 12.8 4.6 7.7 12.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) MscS_TM PF12794.7 CDJ49306.1 - 4.3 6.1 14.9 4.7 6.0 14.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Ctr PF04145.15 CDJ49306.1 - 4.3 7.9 6.7 4.8 7.8 6.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family PIP5K PF01504.18 CDJ49306.1 - 5.7 6.1 8.9 6.3 5.9 8.9 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Exonuc_VII_L PF02601.15 CDJ49307.1 - 0.043 13.4 12.6 0.04 13.5 12.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SUIM_assoc PF16619.5 CDJ49307.1 - 1 9.5 0.0 1 9.5 0.0 4.2 1 1 2 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 eIF-3_zeta PF05091.12 CDJ49308.1 - 1.3 7.9 12.3 2 7.3 10.7 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Efg1 PF10153.9 CDJ49309.1 - 4.4 7.7 11.6 0.3 11.5 6.0 1.9 2 0 0 2 2 2 0 rRNA-processing protein Efg1 SCP1201-deam PF14428.6 CDJ49309.1 - 9.3 6.1 10.0 0.42 10.5 1.3 2.9 1 1 2 3 3 3 0 SCP1.201-like deaminase MCM PF00493.23 CDJ49310.1 - 1.8e-92 308.5 0.0 2.5e-92 308.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 CDJ49310.1 - 8.2e-08 31.9 0.1 2.2e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ49310.1 - 1.4e-05 24.9 0.0 4.1e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ49310.1 - 8.6e-05 22.6 0.0 0.00017 21.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDJ49310.1 - 0.032 14.0 0.2 0.52 10.0 0.2 2.4 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ49310.1 - 0.33 11.3 5.5 0.32 11.4 1.6 3.0 2 1 0 2 2 2 0 AAA ATPase domain DUF3446 PF11928.8 CDJ49310.1 - 2 8.8 9.0 7.9 6.9 0.1 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Pex14_N PF04695.13 CDJ49310.1 - 2.3 8.9 9.3 9.1 6.9 1.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.9 CDJ49310.1 - 7.2 6.9 33.1 1.4 9.2 14.4 2.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA EphA2_TM PF14575.6 CDJ49311.1 - 0.023 15.6 1.5 1.1 10.2 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Red1 PF07964.11 CDJ49311.1 - 0.028 12.7 1.2 0.041 12.1 1.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 NDUF_B12 PF08122.12 CDJ49311.1 - 0.031 14.3 0.7 0.26 11.3 0.3 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Isy1 PF06246.12 CDJ49311.1 - 0.071 12.7 6.0 0.14 11.7 6.0 1.4 1 0 0 1 1 1 0 Isy1-like splicing family DFRP_C PF16543.5 CDJ49311.1 - 0.15 12.5 1.8 5.8 7.5 0.4 2.5 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 RskA PF10099.9 CDJ49311.1 - 0.55 10.5 48.7 0.09 13.1 7.4 3.1 1 1 2 3 3 3 0 Anti-sigma-K factor rskA DUF4259 PF14078.6 CDJ49311.1 - 0.96 10.2 7.9 1.4 9.7 2.6 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4259) PIN_3 PF13470.6 CDJ49311.1 - 3.1 8.6 7.0 0.39 11.5 2.2 1.9 2 0 0 2 2 2 0 PIN domain CDC27 PF09507.10 CDJ49311.1 - 7.8 5.8 19.2 2 7.7 15.0 1.8 1 1 1 2 2 2 0 DNA polymerase subunit Cdc27 PP2C PF00481.21 CDJ49312.1 - 5e-23 82.0 0.1 2.5e-19 69.9 0.0 3.2 3 1 0 3 3 3 2 Protein phosphatase 2C Apt1 PF10351.9 CDJ49312.1 - 1.2 7.9 27.1 0.57 9.0 17.3 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain zf-C3HC4_2 PF13923.6 CDJ49313.1 - 9.2e-06 25.4 3.6 9.2e-06 25.4 3.6 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ49313.1 - 4.3e-05 23.8 6.6 4.3e-05 23.8 6.6 4.0 4 0 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ49313.1 - 0.00021 21.2 2.5 0.00021 21.2 2.5 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ49313.1 - 0.00042 20.1 6.4 0.00042 20.1 6.4 4.0 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ49313.1 - 0.0053 16.6 6.1 0.0053 16.6 6.1 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SPX PF03105.19 CDJ49313.1 - 0.0075 16.2 0.6 0.0075 16.2 0.6 10.2 5 2 1 6 6 6 1 SPX domain zf-C3HC4_4 PF15227.6 CDJ49313.1 - 0.0096 16.1 6.7 0.0096 16.1 6.7 4.8 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING RskA PF10099.9 CDJ49313.1 - 0.038 14.3 0.1 0.038 14.3 0.1 15.7 6 4 3 10 10 10 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ49314.1 - 0.00093 18.9 13.8 0.00093 18.9 13.8 15.6 5 4 8 14 14 14 1 Spt20 family DIX PF00778.17 CDJ49315.1 - 1.7e-05 24.5 0.0 3.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 DIX domain TFIIA PF03153.13 CDJ49315.1 - 0.00031 20.9 7.2 0.00034 20.7 7.2 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit API5 PF05918.11 CDJ49315.1 - 0.018 13.9 2.9 0.025 13.4 2.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Spt20 PF12090.8 CDJ49315.1 - 0.03 13.9 10.6 0.041 13.5 10.6 1.1 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ49315.1 - 0.058 13.7 17.6 0.095 13.0 17.6 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA RAB3GAP2_N PF14655.6 CDJ49315.1 - 0.27 10.4 2.4 0.34 10.1 2.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FTZ PF03867.14 CDJ49315.1 - 2.5 7.5 11.3 1 8.8 8.6 1.6 1 1 1 2 2 2 0 Fushi tarazu (FTZ), N-terminal region DivIC PF04977.15 CDJ49315.1 - 4.6 7.1 10.0 6.8 6.5 10.0 1.2 1 0 0 1 1 1 0 Septum formation initiator SR-25 PF10500.9 CDJ49316.1 - 0.0028 17.3 15.3 0.0028 17.3 15.3 8.0 7 1 1 8 8 8 3 Nuclear RNA-splicing-associated protein CBP_BcsG PF11658.8 CDJ49317.1 - 0.015 13.8 0.0 0.015 13.8 0.0 1.7 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsG Wzy_C PF04932.15 CDJ49317.1 - 0.017 14.8 0.0 0.02 14.6 0.0 1.3 1 1 0 1 1 1 0 O-Antigen ligase YfhO PF09586.10 CDJ49317.1 - 0.025 12.9 0.0 0.04 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial membrane protein YfhO tRNA_anti-like PF12869.7 CDJ49317.1 - 0.036 13.7 1.6 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 tRNA_anti-like RAG2 PF03089.14 CDJ49317.1 - 0.062 12.3 0.5 0.097 11.6 0.5 1.2 1 0 0 1 1 1 0 Recombination activating protein 2 GBV-C_env PF12786.7 CDJ49317.1 - 0.5 9.0 2.9 0.67 8.6 2.9 1.3 1 0 0 1 1 1 0 GB virus C genotype envelope CDC45 PF02724.14 CDJ49317.1 - 0.55 8.5 24.0 0.65 8.2 24.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4604 PF15377.6 CDJ49317.1 - 0.87 10.0 24.7 1.1 9.6 24.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Sporozoite_P67 PF05642.11 CDJ49317.1 - 1 7.3 10.3 1.6 6.7 10.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apt1 PF10351.9 CDJ49317.1 - 4 6.2 16.8 4.8 5.9 16.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Merozoite_SPAM PF07133.11 CDJ49317.1 - 5.8 6.9 24.4 0.6 10.1 9.8 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Peroxin-13_N PF04088.13 CDJ49317.1 - 7.3 6.9 6.7 25 5.1 0.0 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region RskA PF10099.9 CDJ49319.1 - 0.0017 18.7 18.5 0.0017 18.7 18.5 3.3 1 1 2 3 3 3 1 Anti-sigma-K factor rskA FKS1_dom1 PF14288.6 CDJ49319.1 - 0.04 14.2 0.7 0.075 13.4 0.7 1.5 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 eIF-3_zeta PF05091.12 CDJ49319.1 - 0.04 12.9 6.4 0.051 12.6 6.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ49319.1 - 0.069 14.1 7.9 0.24 12.4 6.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ49319.1 - 0.26 9.2 5.7 0.39 8.6 5.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ49319.1 - 0.29 10.9 4.6 0.19 11.5 3.0 1.5 2 0 0 2 2 2 0 Connexin EMC3_TMCO1 PF01956.16 CDJ49319.1 - 3.6 7.3 9.6 5.9 6.6 9.6 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2339 PF10101.9 CDJ49319.1 - 4.1 5.9 32.2 6.6 5.2 32.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Hamartin PF04388.12 CDJ49321.1 - 0.02 13.6 38.1 0.033 12.9 38.1 1.3 1 0 0 1 1 1 0 Hamartin protein Caldesmon PF02029.15 CDJ49321.1 - 0.23 10.2 38.7 0.38 9.5 38.7 1.2 1 0 0 1 1 1 0 Caldesmon LMBR1 PF04791.16 CDJ49321.1 - 0.69 8.7 23.1 0.016 14.1 16.0 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein SART-1 PF03343.13 CDJ49321.1 - 2.1 6.8 43.9 4.3 5.8 43.9 1.4 1 0 0 1 1 1 0 SART-1 family PP2C PF00481.21 CDJ49322.1 - 1.3e-22 80.7 0.0 2.8e-09 37.0 0.0 3.1 1 1 1 2 2 2 2 Protein phosphatase 2C CwsA PF10814.8 CDJ49322.1 - 0.19 11.9 8.3 0.15 12.2 3.4 2.4 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA Chorion_2 PF03964.15 CDJ49322.1 - 1.5 9.7 6.7 0.37 11.6 2.2 2.1 2 0 0 2 2 2 0 Chorion family 2 hEGF PF12661.7 CDJ49323.1 - 0.064 13.9 5.6 0.064 13.9 5.6 3.6 4 0 0 4 4 4 0 Human growth factor-like EGF EGF_3 PF12947.7 CDJ49323.1 - 0.24 11.6 14.9 0.94 9.7 4.9 3.6 2 2 1 3 3 3 0 EGF domain DUF3306 PF11748.8 CDJ49323.1 - 0.52 11.2 4.0 1 10.3 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Ribosomal_60s PF00428.19 CDJ49323.1 - 0.71 10.5 11.9 1.6 9.3 11.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein SUIM_assoc PF16619.5 CDJ49323.1 - 1.7 8.8 11.7 0.33 11.0 7.1 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RAP1 PF07218.11 CDJ49323.1 - 5.8 5.1 4.9 8.2 4.6 4.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Shadoo PF14999.6 CDJ49323.1 - 9.4 6.3 15.9 10 6.2 8.7 2.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Ldh_1_N PF00056.23 CDJ49324.1 - 1.9e-35 122.0 1.1 2.6e-35 121.6 0.3 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDJ49324.1 - 3.4e-32 111.7 0.0 3.2e-31 108.5 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 CDJ49324.1 - 1.7e-05 24.5 0.0 8.8e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase NAD_binding_8 PF13450.6 CDJ49324.1 - 0.0023 18.1 0.0 0.0059 16.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DSHCT PF08148.12 CDJ49324.1 - 0.0078 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Glyco_hydro_4C PF11975.8 CDJ49324.1 - 0.14 12.2 0.1 0.45 10.6 0.1 1.8 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Phage_XkdX PF09693.10 CDJ49324.1 - 0.15 12.1 0.4 0.35 10.9 0.4 1.6 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) adh_short PF00106.25 CDJ49327.1 - 1.6e-09 37.5 27.6 4.1e-05 23.1 0.4 5.9 5 2 1 6 6 6 3 short chain dehydrogenase SUIM_assoc PF16619.5 CDJ49327.1 - 0.021 14.9 1.0 0.021 14.9 1.0 6.0 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 SPX PF03105.19 CDJ49327.1 - 0.051 13.5 16.7 0.18 11.7 0.1 3.0 2 1 0 2 2 2 0 SPX domain SR-25 PF10500.9 CDJ49327.1 - 0.9 9.1 43.7 0.38 10.3 2.4 3.6 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein PIP5K PF01504.18 CDJ49327.1 - 1.3 8.2 9.7 1.2 8.3 5.5 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Band_3_cyto PF07565.13 CDJ49327.1 - 3.6 7.3 17.1 6.5 6.5 11.2 2.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain SARAF PF06682.12 CDJ49327.1 - 9 5.8 25.9 1 9.0 9.8 3.4 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis TFIIA PF03153.13 CDJ49329.1 - 0.0035 17.4 37.9 0.0037 17.3 37.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ49329.1 - 0.0044 16.5 14.6 0.0044 16.5 14.6 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) V_ATPase_I PF01496.19 CDJ49329.1 - 0.0045 15.0 13.2 0.0039 15.2 13.2 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3402 PF11882.8 CDJ49329.1 - 0.0056 15.8 13.9 0.0077 15.4 13.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) Eapp_C PF10238.9 CDJ49329.1 - 0.0065 16.6 10.8 0.0079 16.3 10.8 1.3 1 0 0 1 1 1 1 E2F-associated phosphoprotein TRAP_alpha PF03896.16 CDJ49329.1 - 0.0066 15.7 4.7 0.0066 15.7 4.7 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF5308 PF17233.2 CDJ49329.1 - 0.0075 16.5 8.3 0.0079 16.4 8.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5308) PPL5 PF18168.1 CDJ49329.1 - 0.0081 15.5 8.1 0.0095 15.3 8.1 1.1 1 0 0 1 1 1 1 Prim-pol family 5 Presenilin PF01080.17 CDJ49329.1 - 0.0091 14.8 16.8 0.0091 14.8 16.8 1.1 1 0 0 1 1 1 1 Presenilin FAM76 PF16046.5 CDJ49329.1 - 0.0095 15.3 21.7 0.011 15.1 21.7 1.0 1 0 0 1 1 1 1 FAM76 protein MMM1 PF10296.9 CDJ49329.1 - 0.019 14.1 7.9 0.018 14.1 7.9 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DUF2828 PF11443.8 CDJ49329.1 - 0.024 12.8 13.3 0.023 12.8 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Gti1_Pac2 PF09729.9 CDJ49329.1 - 0.024 14.7 12.5 0.029 14.5 12.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family CLN3 PF02487.17 CDJ49329.1 - 0.037 13.1 13.4 0.041 12.9 13.4 1.1 1 0 0 1 1 1 0 CLN3 protein EPL1 PF10513.9 CDJ49329.1 - 0.049 14.0 16.0 0.058 13.8 16.0 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like MMR1 PF08505.10 CDJ49329.1 - 0.056 13.7 21.0 0.061 13.6 21.0 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Connexin PF00029.19 CDJ49329.1 - 0.057 13.2 13.2 0.07 12.9 13.2 1.2 1 0 0 1 1 1 0 Connexin DUF908 PF06012.12 CDJ49329.1 - 0.067 12.6 14.6 0.076 12.4 14.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) EIIBC-GUT_N PF03612.14 CDJ49329.1 - 0.08 12.7 14.2 0.11 12.2 14.2 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF913 PF06025.12 CDJ49329.1 - 0.088 11.8 9.3 0.093 11.7 9.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MMU163 PF17119.5 CDJ49329.1 - 0.092 11.9 5.2 0.1 11.7 5.2 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF4638 PF15472.6 CDJ49329.1 - 0.1 12.3 15.6 0.12 12.0 15.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) NARP1 PF12569.8 CDJ49329.1 - 0.12 11.3 16.6 0.12 11.2 16.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 eIF-3_zeta PF05091.12 CDJ49329.1 - 0.12 11.3 23.3 0.14 11.1 23.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ49329.1 - 0.13 12.3 22.8 0.17 11.9 22.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EOS1 PF12326.8 CDJ49329.1 - 0.13 12.2 11.3 0.16 11.9 11.3 1.2 1 0 0 1 1 1 0 N-glycosylation protein Hid1 PF12722.7 CDJ49329.1 - 0.14 10.3 15.6 0.13 10.4 15.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4628 PF15429.6 CDJ49329.1 - 0.16 11.6 14.9 0.21 11.3 14.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Serinc PF03348.15 CDJ49329.1 - 0.18 10.7 13.2 0.21 10.5 13.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2370 PF10176.9 CDJ49329.1 - 0.22 11.1 6.2 0.23 11.0 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Tim54 PF11711.8 CDJ49329.1 - 0.25 10.1 14.7 0.28 9.9 14.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 CDJ49329.1 - 0.26 11.3 15.4 0.35 10.9 15.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ49329.1 - 0.29 10.9 19.9 0.41 10.4 19.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nucleoside_tran PF01733.18 CDJ49329.1 - 0.32 10.3 4.7 0.34 10.2 4.7 1.1 1 0 0 1 1 1 0 Nucleoside transporter NPR3 PF03666.13 CDJ49329.1 - 0.33 9.7 15.5 0.34 9.6 15.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4407 PF14362.6 CDJ49329.1 - 0.34 10.2 20.1 0.42 9.9 20.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AIF_C PF14721.6 CDJ49329.1 - 0.35 11.2 12.5 0.52 10.7 12.5 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term OATP PF03137.20 CDJ49329.1 - 0.35 9.1 7.6 0.36 9.0 7.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Bul1_N PF04425.12 CDJ49329.1 - 0.36 9.5 14.1 0.38 9.4 14.1 1.1 1 0 0 1 1 1 0 Bul1 N terminus SID-1_RNA_chan PF13965.6 CDJ49329.1 - 0.37 9.2 9.7 0.39 9.1 9.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PepSY_TM PF03929.16 CDJ49329.1 - 0.38 10.4 7.3 0.4 10.3 7.3 1.1 1 0 0 1 1 1 0 PepSY-associated TM region HSNSD PF12062.8 CDJ49329.1 - 0.4 9.4 9.2 0.44 9.2 9.2 1.1 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase DUF4228 PF14009.6 CDJ49329.1 - 0.42 11.0 6.4 0.46 10.9 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Zip PF02535.22 CDJ49329.1 - 0.43 9.7 5.0 0.41 9.8 5.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3043 PF11241.8 CDJ49329.1 - 0.44 10.6 10.2 0.58 10.2 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) MLANA PF14991.6 CDJ49329.1 - 0.48 10.7 7.3 0.83 9.9 7.3 1.4 1 0 0 1 1 1 0 Protein melan-A ALMT PF11744.8 CDJ49329.1 - 0.5 9.1 13.6 0.52 9.1 13.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ49329.1 - 0.5 9.3 19.2 0.55 9.2 19.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 CDJ49329.1 - 0.5 8.6 14.3 0.49 8.6 14.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MCD PF05292.11 CDJ49329.1 - 0.54 9.8 8.5 0.66 9.5 8.5 1.1 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain AAA_11 PF13086.6 CDJ49329.1 - 0.54 10.0 19.0 0.62 9.8 19.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2126 PF09899.9 CDJ49329.1 - 0.55 8.2 11.1 0.59 8.1 11.1 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) MDM10 PF12519.8 CDJ49329.1 - 0.61 8.9 14.8 0.63 8.8 14.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF778 PF05608.12 CDJ49329.1 - 0.62 10.4 10.4 0.71 10.2 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF778) CobT PF06213.12 CDJ49329.1 - 0.66 9.3 26.9 0.88 8.9 26.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_P35 PF03213.14 CDJ49329.1 - 0.68 9.1 3.8 0.79 8.9 3.8 1.1 1 0 0 1 1 1 0 Poxvirus P35 protein GREB1 PF15782.5 CDJ49329.1 - 0.73 6.9 15.6 0.72 6.9 15.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ureide_permease PF07168.11 CDJ49329.1 - 0.75 8.5 8.2 0.87 8.3 8.2 1.1 1 0 0 1 1 1 0 Ureide permease Stig1 PF04885.13 CDJ49329.1 - 0.75 10.3 10.9 1.1 9.8 10.9 1.3 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Scs3p PF10261.9 CDJ49329.1 - 0.86 9.1 4.4 0.97 8.9 4.4 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Peptidase_S64 PF08192.11 CDJ49329.1 - 0.92 7.9 19.1 1.1 7.7 19.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF1387 PF07139.11 CDJ49329.1 - 1.1 9.0 22.9 2 8.1 22.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1387) DUF4175 PF13779.6 CDJ49329.1 - 1.1 7.1 43.7 1.3 6.9 43.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.9 CDJ49329.1 - 1.2 7.3 32.4 1.3 7.2 32.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Membralin PF09746.9 CDJ49329.1 - 1.4 7.9 12.1 1.4 7.9 12.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein Acatn PF13000.7 CDJ49329.1 - 1.7 7.1 4.5 1.9 6.9 4.5 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 Mem_trans PF03547.18 CDJ49329.1 - 1.8 6.8 6.1 2 6.7 6.1 1.1 1 0 0 1 1 1 0 Membrane transport protein Kei1 PF08552.11 CDJ49329.1 - 1.9 8.3 12.1 2.3 8.0 12.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DNApol_Exo PF18136.1 CDJ49329.1 - 2.1 7.4 15.2 2.6 7.1 15.2 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Folate_carrier PF01770.18 CDJ49329.1 - 2.3 6.9 9.3 2.7 6.6 9.3 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF2514 PF10721.9 CDJ49329.1 - 2.4 8.2 18.2 3.2 7.8 18.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) HSP70 PF00012.20 CDJ49329.1 - 2.4 6.2 16.6 2.8 6.0 16.6 1.2 1 0 0 1 1 1 0 Hsp70 protein CSG2 PF16965.5 CDJ49329.1 - 2.4 7.0 10.3 2.8 6.8 10.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator HCO3_cotransp PF00955.21 CDJ49329.1 - 2.5 6.8 7.7 2.6 6.7 7.7 1.1 1 0 0 1 1 1 0 HCO3- transporter family Baculo_PP31 PF05311.11 CDJ49329.1 - 2.6 7.4 18.7 3.7 6.9 18.7 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Het-C PF07217.11 CDJ49329.1 - 2.7 6.4 10.8 3.1 6.2 10.8 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Tmp39 PF10271.9 CDJ49329.1 - 2.7 6.9 5.6 2.9 6.8 5.6 1.1 1 0 0 1 1 1 0 Putative transmembrane protein HemX PF04375.14 CDJ49329.1 - 3.3 6.9 36.7 4.2 6.5 36.7 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Ndc1_Nup PF09531.10 CDJ49329.1 - 3.5 6.2 17.6 3.9 6.1 17.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup K_trans PF02705.16 CDJ49329.1 - 3.7 5.9 4.4 4.8 5.6 4.4 1.3 1 0 0 1 1 1 0 K+ potassium transporter UPF0560 PF10577.9 CDJ49329.1 - 3.7 5.9 26.5 4.3 5.7 26.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Cellulose_synt PF03552.14 CDJ49329.1 - 4.2 5.7 7.4 4.3 5.7 7.4 1.1 1 0 0 1 1 1 0 Cellulose synthase Otopetrin PF03189.13 CDJ49329.1 - 4.5 6.0 12.1 5.4 5.7 12.1 1.1 1 0 0 1 1 1 0 Otopetrin DUF4192 PF13830.6 CDJ49329.1 - 4.9 7.1 6.0 5 7.1 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) SPG4 PF17325.2 CDJ49329.1 - 5.4 8.1 15.9 11 7.2 15.9 1.5 1 0 0 1 1 1 0 Stationary phase protein 4 CAF1 PF04857.20 CDJ49329.1 - 5.8 6.0 15.3 7.8 5.6 15.3 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease Exonuc_VII_L PF02601.15 CDJ49329.1 - 5.9 6.4 23.4 7.2 6.1 23.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pannexin_like PF12534.8 CDJ49329.1 - 6 5.9 14.8 7.5 5.5 14.8 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 FliP PF00813.20 CDJ49329.1 - 6.4 6.6 7.9 7.2 6.4 7.9 1.3 1 0 0 1 1 1 0 FliP family Peptidase_S15 PF02129.18 CDJ49329.1 - 8 6.0 13.4 10 5.6 13.4 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) TMPIT PF07851.13 CDJ49329.1 - 9.3 5.4 22.1 11 5.2 22.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein MAJIN PF15077.6 CDJ49329.1 - 9.5 5.9 13.5 11 5.7 13.5 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF2802 PF10975.8 CDJ49331.1 - 1.3 9.2 4.3 3.4 7.9 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Peptidase_S9_N PF02897.15 CDJ49332.1 - 1.3e-51 175.7 0.7 1.5e-51 175.6 0.7 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain MAGE_N PF12440.8 CDJ49333.1 - 1.5 9.6 15.1 3.2 8.5 15.1 1.8 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal DUF4602 PF15375.6 CDJ49333.1 - 7 7.0 12.9 6.6 7.1 9.9 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4602) DUF2722 PF10846.8 CDJ49334.1 - 0.00085 18.4 2.5 0.00085 18.4 2.5 5.6 6 0 0 6 6 6 3 Protein of unknown function (DUF2722) MAGE PF01454.19 CDJ49334.1 - 5.5 6.6 9.2 4.7 6.8 0.9 2.8 2 0 0 2 2 2 0 MAGE family OATP PF03137.20 CDJ49334.1 - 9 4.5 5.0 12 4.0 0.1 2.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FlgN PF05130.12 CDJ49335.1 - 7.8e-05 23.2 12.8 7.8e-05 23.2 12.8 6.4 4 1 2 6 6 6 1 FlgN protein TPR_MLP1_2 PF07926.12 CDJ49335.1 - 0.0059 16.7 17.9 0.0059 16.7 17.9 8.4 6 2 3 9 9 9 1 TPR/MLP1/MLP2-like protein EELM2 PF15863.5 CDJ49336.1 - 1.7e-60 204.1 0.0 2.6e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 Extended EGL-27 and MTA1 homology domain PolC_DP2 PF03833.13 CDJ49336.1 - 0.11 10.3 5.5 0.15 9.9 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Pre-PUA PF17832.1 CDJ49337.1 - 7.6e-26 90.6 0.0 2.9e-25 88.7 0.0 1.8 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 CDJ49337.1 - 9.7e-06 25.5 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 CDJ49337.1 - 0.016 15.5 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) S10_plectin PF03501.15 CDJ49338.1 - 5.6e-39 132.1 0.3 6.8e-39 131.8 0.3 1.1 1 0 0 1 1 1 1 Plectin/S10 domain zf-CCCH PF00642.24 CDJ49339.1 - 0.044 13.7 2.4 0.044 13.7 2.4 3.6 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.9 CDJ49339.1 - 0.058 13.1 4.9 2.8 7.7 0.3 3.0 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 CDJ49339.1 - 0.14 12.7 10.2 8.4 7.0 0.3 3.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Med8 PF10232.9 CDJ49339.1 - 2.3 7.8 5.3 1.2 8.7 3.1 1.7 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Endostatin PF06482.11 CDJ49340.1 - 0.00018 21.1 10.5 0.00018 21.1 10.5 1.9 2 0 0 2 2 2 1 Collagenase NC10 and Endostatin DDHD PF02862.17 CDJ49340.1 - 0.00023 21.4 8.9 0.0024 18.1 8.2 2.3 2 0 0 2 2 2 1 DDHD domain CobT PF06213.12 CDJ49340.1 - 0.0012 18.3 23.3 0.0012 18.3 23.3 2.3 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 CDJ49340.1 - 0.0019 17.3 4.6 0.0019 17.3 4.6 1.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) FAM60A PF15396.6 CDJ49340.1 - 0.002 18.2 9.2 0.002 18.2 9.2 1.9 2 0 0 2 2 2 1 Protein Family FAM60A Spt20 PF12090.8 CDJ49340.1 - 0.0064 16.1 2.6 0.0064 16.1 2.6 3.1 2 1 0 2 2 1 1 Spt20 family Zip PF02535.22 CDJ49340.1 - 0.0068 15.7 18.1 0.0068 15.7 18.1 1.8 2 0 0 2 2 2 1 ZIP Zinc transporter Ctr PF04145.15 CDJ49340.1 - 0.009 16.6 7.8 0.045 14.4 6.9 2.2 2 0 0 2 2 2 1 Ctr copper transporter family SID-1_RNA_chan PF13965.6 CDJ49340.1 - 0.013 13.9 2.8 0.02 13.3 2.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HCO3_cotransp PF00955.21 CDJ49340.1 - 0.015 14.1 6.5 0.024 13.5 6.5 1.2 1 0 0 1 1 1 0 HCO3- transporter family Velvet PF11754.8 CDJ49340.1 - 0.041 13.8 18.6 0.33 10.8 17.7 2.1 2 0 0 2 2 2 0 Velvet factor DUF2370 PF10176.9 CDJ49340.1 - 0.044 13.4 8.5 0.02 14.5 6.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF2052 PF09747.9 CDJ49340.1 - 0.055 13.6 24.4 0.52 10.4 22.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) MecA PF05389.12 CDJ49340.1 - 0.063 12.9 15.2 0.79 9.3 15.0 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) MMU163 PF17119.5 CDJ49340.1 - 0.079 12.1 7.9 0.033 13.4 5.3 1.6 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis DUF4366 PF14283.6 CDJ49340.1 - 0.16 12.0 9.4 0.78 9.8 7.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF2126 PF09899.9 CDJ49340.1 - 0.23 9.5 12.9 0.4 8.7 12.9 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Neur_chan_memb PF02932.16 CDJ49340.1 - 0.31 11.1 20.4 0.87 9.6 18.7 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 CDJ49340.1 - 0.32 9.7 18.4 0.014 14.2 12.2 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 MID_MedPIWI PF18296.1 CDJ49340.1 - 0.32 10.7 19.5 2.2 8.0 18.7 2.1 2 0 0 2 2 2 0 MID domain of medPIWI CSG2 PF16965.5 CDJ49340.1 - 0.34 9.8 9.5 0.74 8.7 9.5 1.5 1 0 0 1 1 1 0 Ceramide synthase regulator Presenilin PF01080.17 CDJ49340.1 - 0.39 9.4 31.7 2.9 6.6 31.6 1.9 2 0 0 2 2 2 0 Presenilin CLN3 PF02487.17 CDJ49340.1 - 0.7 8.9 18.3 0.96 8.4 17.0 1.8 2 0 0 2 2 2 0 CLN3 protein PAT1 PF09770.9 CDJ49340.1 - 0.72 8.1 46.0 0.18 10.1 38.6 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Mem_trans PF03547.18 CDJ49340.1 - 0.78 8.1 4.5 6.3 5.1 4.9 2.0 2 0 0 2 2 2 0 Membrane transport protein Pex14_N PF04695.13 CDJ49340.1 - 0.96 10.1 43.4 0.27 11.9 30.1 2.6 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM222A PF15258.6 CDJ49340.1 - 0.98 8.4 39.0 0.41 9.7 31.7 2.2 2 0 0 2 2 2 0 Protein family of FAM222A Peptidase_S15 PF02129.18 CDJ49340.1 - 1.1 8.8 17.7 1 8.9 14.4 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) LAP1C PF05609.12 CDJ49340.1 - 1.1 8.3 23.1 0.21 10.6 18.8 1.8 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) RR_TM4-6 PF06459.12 CDJ49340.1 - 1.7 8.4 28.7 0.068 13.0 21.3 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 CDJ49340.1 - 1.8 6.4 29.6 1.5 6.6 26.9 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TCP PF03634.13 CDJ49340.1 - 2.4 8.7 25.3 1.7 9.2 20.7 2.2 2 0 0 2 2 2 0 TCP family transcription factor Rtf2 PF04641.12 CDJ49340.1 - 2.9 7.2 21.9 0.73 9.1 17.8 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger RIFIN PF02009.16 CDJ49340.1 - 3 7.6 17.8 0.99 9.2 9.2 2.4 2 1 0 2 2 2 0 Rifin PepSY_TM PF03929.16 CDJ49340.1 - 4.1 7.0 14.6 6.2 6.4 9.9 2.4 2 0 0 2 2 2 0 PepSY-associated TM region Connexin PF00029.19 CDJ49340.1 - 4.3 7.0 19.7 2.4 7.9 16.4 2.1 2 0 0 2 2 2 0 Connexin BORG_CEP PF14957.6 CDJ49340.1 - 5.2 8.2 18.9 1.9 9.7 14.9 2.0 2 0 0 2 2 2 0 Cdc42 effector NPR3 PF03666.13 CDJ49340.1 - 5.2 5.7 26.9 4 6.1 23.9 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Ureide_permease PF07168.11 CDJ49340.1 - 6.2 5.5 9.7 13 4.4 9.7 1.5 1 0 0 1 1 1 0 Ureide permease Paramyxo_ncap PF00973.19 CDJ49340.1 - 6.5 5.5 19.6 12 4.7 19.6 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TT_ORF1 PF02956.14 CDJ49340.1 - 6.8 5.2 17.1 0.067 11.9 9.5 1.4 2 0 0 2 2 1 0 TT viral orf 1 Kei1 PF08552.11 CDJ49340.1 - 7 6.5 16.9 9.5 6.1 14.5 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Exonuc_VII_L PF02601.15 CDJ49340.1 - 7 6.1 27.0 20 4.6 24.7 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Gti1_Pac2 PF09729.9 CDJ49340.1 - 8.5 6.4 25.1 62 3.6 25.0 2.0 2 0 0 2 2 2 0 Gti1/Pac2 family Fez1 PF06818.15 CDJ49342.1 - 0.00013 22.5 17.4 0.00013 22.5 17.4 3.1 2 1 1 3 3 3 1 Fez1 Spc7 PF08317.11 CDJ49342.1 - 0.0016 17.4 39.6 0.0016 17.4 39.6 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein OmpH PF03938.14 CDJ49342.1 - 0.0036 17.6 37.5 0.0036 17.6 37.5 3.7 2 1 2 4 4 4 1 Outer membrane protein (OmpH-like) PCRF PF03462.18 CDJ49342.1 - 0.033 14.0 44.2 0.26 11.1 22.7 2.2 2 0 0 2 2 2 0 PCRF domain HOOK PF05622.12 CDJ49342.1 - 0.79 7.8 84.3 0.0069 14.6 54.0 2.0 1 1 1 2 2 2 0 HOOK protein Tropomyosin PF00261.20 CDJ49342.1 - 2.5 7.4 63.1 0.018 14.4 15.9 2.2 2 0 0 2 2 2 0 Tropomyosin YvrJ PF12841.7 CDJ49342.1 - 7.2 6.2 7.8 5 6.7 0.1 3.2 3 0 0 3 3 3 0 YvrJ protein family CNDH2_C PF16858.5 CDJ49343.1 - 0.00037 20.5 36.2 0.021 14.7 18.3 2.1 2 0 0 2 2 2 2 Condensin II complex subunit CAP-H2 or CNDH2, C-term AF-4 PF05110.13 CDJ49343.1 - 0.00091 17.5 72.7 0.042 12.0 35.1 2.0 2 0 0 2 2 2 2 AF-4 proto-oncoprotein SRP-alpha_N PF04086.13 CDJ49343.1 - 0.0041 17.1 11.9 0.0041 17.1 11.9 2.3 2 0 0 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal DUF2052 PF09747.9 CDJ49343.1 - 0.072 13.2 39.2 0.17 12.0 11.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Cwf_Cwc_15 PF04889.12 CDJ49343.1 - 0.35 10.6 47.7 1.3 8.8 22.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF572 PF04502.13 CDJ49343.1 - 4.2 6.9 44.2 1.6 8.3 13.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF5427 PF10310.9 CDJ49343.1 - 6.5 5.6 44.3 1.4 7.8 23.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Nop53 PF07767.11 CDJ49343.1 - 6.9 5.9 47.0 1.8 7.9 9.1 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) AAA_11 PF13086.6 CDJ49343.1 - 7.1 6.3 34.4 6.2 6.5 16.5 2.3 2 0 0 2 2 2 0 AAA domain TMEM154 PF15102.6 CDJ49344.1 - 0.044 13.7 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Pinin_SDK_memA PF04696.13 CDJ49345.1 - 1.4e-05 25.1 21.5 1.4e-05 25.1 21.5 2.3 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region RskA PF10099.9 CDJ49345.1 - 2.3e-05 24.8 0.4 2.3e-05 24.8 0.4 2.5 2 1 1 3 3 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ49345.1 - 6.5e-05 23.1 64.8 0.0094 16.0 22.0 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ49345.1 - 0.00014 22.5 40.0 0.0023 18.6 15.1 2.3 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region BRF1 PF07741.13 CDJ49345.1 - 0.00021 21.6 18.6 0.035 14.4 9.0 2.5 2 0 0 2 2 2 2 Brf1-like TBP-binding domain FmiP_Thoc5 PF09766.9 CDJ49345.1 - 0.0005 19.5 11.9 0.0005 19.5 11.9 2.1 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 SpoIIP PF07454.11 CDJ49345.1 - 0.00078 19.0 25.7 0.011 15.3 11.5 2.1 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) DUF3043 PF11241.8 CDJ49345.1 - 0.0022 18.1 16.2 0.13 12.2 3.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3043) CCDC53 PF10152.9 CDJ49345.1 - 0.0022 18.4 23.6 0.086 13.3 10.9 2.3 2 0 0 2 2 2 2 Subunit CCDC53 of WASH complex Afi1 PF07792.12 CDJ49345.1 - 0.0031 18.0 28.5 0.094 13.2 5.2 2.2 2 0 0 2 2 2 2 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2052 PF09747.9 CDJ49345.1 - 0.0034 17.5 27.1 0.13 12.3 14.7 2.1 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ49345.1 - 0.0038 17.1 23.8 0.068 13.0 12.1 2.1 2 0 0 2 2 2 2 Ryanodine Receptor TM 4-6 HGTP_anticodon2 PF12745.7 CDJ49345.1 - 0.0042 16.6 12.3 0.0042 16.6 12.3 2.1 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs EPL1 PF10513.9 CDJ49345.1 - 0.0054 17.1 25.2 0.0091 16.4 9.8 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like Velvet PF11754.8 CDJ49345.1 - 0.0075 16.2 19.7 0.21 11.5 8.7 2.1 2 0 0 2 2 2 2 Velvet factor Connexin PF00029.19 CDJ49345.1 - 0.011 15.5 23.4 0.16 11.7 10.7 2.1 2 0 0 2 2 2 0 Connexin CSG2 PF16965.5 CDJ49345.1 - 0.011 14.7 18.5 0.01 14.8 5.9 2.0 1 1 0 2 2 2 0 Ceramide synthase regulator DUF572 PF04502.13 CDJ49345.1 - 0.013 15.1 17.8 0.31 10.6 1.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) TERB2 PF15101.6 CDJ49345.1 - 0.015 15.4 39.8 0.28 11.2 18.1 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DAG_kinase_N PF14513.6 CDJ49345.1 - 0.015 15.5 22.3 0.3 11.3 12.3 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF5523 PF17661.1 CDJ49345.1 - 0.017 14.9 27.5 0.089 12.5 14.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Gti1_Pac2 PF09729.9 CDJ49345.1 - 0.021 14.9 17.8 0.069 13.2 7.2 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family CPSF100_C PF13299.6 CDJ49345.1 - 0.024 14.8 21.1 0.18 12.0 10.8 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 CDJ49345.1 - 0.027 13.5 13.6 0.089 11.8 7.8 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Tim54 PF11711.8 CDJ49345.1 - 0.032 13.0 20.5 0.018 13.8 7.6 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pet20 PF08692.10 CDJ49345.1 - 0.036 14.8 11.0 1.4 9.7 4.6 2.3 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Pkinase_fungal PF17667.1 CDJ49345.1 - 0.036 12.8 10.7 0.051 12.3 2.5 2.1 2 0 0 2 2 2 0 Fungal protein kinase FAM91_C PF14648.6 CDJ49345.1 - 0.036 12.9 12.6 0.046 12.6 2.6 2.0 2 0 0 2 2 2 0 FAM91 C-terminus Rtf2 PF04641.12 CDJ49345.1 - 0.037 13.4 20.7 0.18 11.2 1.6 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger MDM10 PF12519.8 CDJ49345.1 - 0.05 12.5 16.9 0.041 12.8 5.5 2.0 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 BSMAP PF12280.8 CDJ49345.1 - 0.06 13.6 22.3 0.09 13.0 3.9 2.2 2 0 0 2 2 2 0 Brain specific membrane anchored protein RP-C_C PF11800.8 CDJ49345.1 - 0.063 13.4 22.4 0.035 14.2 8.5 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region SLC12 PF03522.15 CDJ49345.1 - 0.063 12.3 26.1 0.41 9.6 12.8 2.0 2 0 0 2 2 2 0 Solute carrier family 12 DUF4770 PF15994.5 CDJ49345.1 - 0.065 13.5 30.9 0.28 11.4 12.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Ctr PF04145.15 CDJ49345.1 - 0.071 13.7 18.0 0.099 13.3 5.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family Membralin PF09746.9 CDJ49345.1 - 0.11 11.6 16.0 0.23 10.5 6.6 2.1 2 0 0 2 2 2 0 Tumour-associated protein DUF2828 PF11443.8 CDJ49345.1 - 0.11 10.6 25.5 0.39 8.7 12.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Sec62 PF03839.16 CDJ49345.1 - 0.12 11.9 20.6 0.17 11.3 7.6 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 Peroxin-13_N PF04088.13 CDJ49345.1 - 0.12 12.6 16.0 1.3 9.3 1.8 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region CNDH2_C PF16858.5 CDJ49345.1 - 0.14 12.1 27.7 0.86 9.4 6.5 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term GAGA_bind PF06217.12 CDJ49345.1 - 0.14 12.4 20.1 0.9 9.8 1.5 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family DUF4366 PF14283.6 CDJ49345.1 - 0.15 12.1 10.3 0.058 13.4 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF4834 PF16118.5 CDJ49345.1 - 0.17 12.9 36.4 0.22 12.5 17.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4746 PF15928.5 CDJ49345.1 - 0.18 11.2 19.5 0.9 8.9 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) BORG_CEP PF14957.6 CDJ49345.1 - 0.18 12.9 15.6 3 9.0 0.7 2.2 2 0 0 2 2 2 0 Cdc42 effector EBP50_C PF09007.11 CDJ49345.1 - 0.18 12.8 19.1 1.3 10.0 1.3 2.2 2 0 0 2 2 2 0 EBP50, C-terminal MMR1 PF08505.10 CDJ49345.1 - 0.19 12.0 40.3 1.2 9.4 20.5 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Eapp_C PF10238.9 CDJ49345.1 - 0.23 11.6 27.0 1.7 8.7 5.6 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein AIF_C PF14721.6 CDJ49345.1 - 0.24 11.8 21.2 1.6 9.1 2.1 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4471 PF14740.6 CDJ49345.1 - 0.25 10.5 20.3 0.12 11.6 6.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) DUF4228 PF14009.6 CDJ49345.1 - 0.31 11.4 13.6 3.1 8.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Band_3_cyto PF07565.13 CDJ49345.1 - 0.34 10.7 27.8 1.6 8.5 14.0 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF3299 PF11736.8 CDJ49345.1 - 0.36 10.8 18.4 0.11 12.5 4.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3299) TCP PF03634.13 CDJ49345.1 - 0.38 11.3 26.5 1.4 9.5 14.0 2.1 2 0 0 2 2 2 0 TCP family transcription factor HNOBA PF07701.14 CDJ49345.1 - 0.41 10.0 23.4 0.4 10.1 8.1 2.3 2 0 0 2 2 2 0 Heme NO binding associated PRC2_HTH_1 PF18118.1 CDJ49345.1 - 0.42 11.4 20.9 0.95 10.3 10.0 2.4 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain PAT1 PF09770.9 CDJ49345.1 - 0.44 8.7 49.2 0.16 10.3 23.2 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 EOS1 PF12326.8 CDJ49345.1 - 0.46 10.4 16.5 2.2 8.2 8.9 2.2 2 0 0 2 2 2 0 N-glycosylation protein Vfa1 PF08432.10 CDJ49345.1 - 0.49 10.7 27.4 2 8.7 14.4 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF719 PF05334.13 CDJ49345.1 - 0.51 10.5 19.5 1.6 8.9 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Spt5_N PF11942.8 CDJ49345.1 - 0.58 11.2 23.6 1.1 10.3 9.0 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PepSY_TM PF03929.16 CDJ49345.1 - 0.68 9.5 17.7 0.34 10.6 4.4 2.2 2 0 0 2 2 2 0 PepSY-associated TM region AP3D1 PF06375.11 CDJ49345.1 - 0.71 10.1 24.5 0.5 10.6 10.2 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Senescence_reg PF04520.13 CDJ49345.1 - 0.75 10.6 14.7 1.3 9.8 5.0 2.2 2 0 0 2 2 2 0 Senescence regulator DUF908 PF06012.12 CDJ49345.1 - 0.78 9.1 19.3 0.18 11.2 8.5 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) FAM176 PF14851.6 CDJ49345.1 - 0.8 9.4 19.0 1.3 8.7 10.1 2.2 2 0 0 2 2 2 0 FAM176 family UPF0560 PF10577.9 CDJ49345.1 - 0.86 8.0 43.1 0.56 8.6 19.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 DUF4638 PF15472.6 CDJ49345.1 - 0.87 9.3 25.8 2.4 7.8 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) SOBP PF15279.6 CDJ49345.1 - 0.93 10.0 29.8 1.8 9.1 10.9 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein CobT PF06213.12 CDJ49345.1 - 0.94 8.8 41.4 0.024 14.0 16.5 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT FliP PF00813.20 CDJ49345.1 - 1 9.2 17.2 3.3 7.6 6.5 2.4 2 0 0 2 2 2 0 FliP family CCSAP PF15748.5 CDJ49345.1 - 1 9.5 30.8 2 8.5 15.9 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF4569 PF15133.6 CDJ49345.1 - 1.1 9.0 31.0 0.76 9.4 12.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) Folate_carrier PF01770.18 CDJ49345.1 - 1.1 8.0 16.5 0.5 9.0 5.0 2.1 2 0 0 2 2 2 0 Reduced folate carrier Rxt3 PF08642.10 CDJ49345.1 - 1.1 10.0 16.9 4.3 8.1 6.5 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 FHIPEP PF00771.20 CDJ49345.1 - 1.2 7.5 21.8 0.46 8.9 3.6 2.2 2 0 0 2 2 2 0 FHIPEP family DUF3807 PF12720.7 CDJ49345.1 - 1.2 9.4 39.5 0.73 10.1 19.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF4050 PF13259.6 CDJ49345.1 - 1.3 9.3 20.8 3.1 8.1 10.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) DUF4045 PF13254.6 CDJ49345.1 - 1.4 8.5 21.0 0.92 9.1 8.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) LAP1C PF05609.12 CDJ49345.1 - 1.5 7.9 26.9 0.22 10.6 9.5 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) GPCR_chapero_1 PF11904.8 CDJ49345.1 - 1.5 8.2 15.4 0.53 9.7 5.3 2.2 2 0 0 2 2 2 0 GPCR-chaperone Lin-8 PF03353.15 CDJ49345.1 - 1.5 8.3 35.4 2.1 7.8 17.9 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Isy1 PF06246.12 CDJ49345.1 - 1.6 8.3 29.3 1.3 8.5 5.8 2.1 2 0 0 2 2 2 0 Isy1-like splicing family CNDH2_M PF16869.5 CDJ49345.1 - 1.7 9.3 18.6 0.53 11.0 4.3 2.4 2 0 0 2 2 2 0 PF16858 Plasmodium_Vir PF05795.11 CDJ49345.1 - 1.7 7.9 13.9 0.29 10.5 3.0 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein PIEZO PF15917.5 CDJ49345.1 - 1.9 7.9 38.6 0.4 10.1 9.7 2.1 2 0 0 2 2 2 0 Piezo FAM60A PF15396.6 CDJ49345.1 - 1.9 8.4 23.8 3.9 7.4 10.8 2.1 2 0 0 2 2 2 0 Protein Family FAM60A NPR3 PF03666.13 CDJ49345.1 - 1.9 7.2 23.5 0.42 9.4 9.8 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 EFTUD2 PF16004.5 CDJ49345.1 - 1.9 9.1 28.8 0.51 10.9 12.2 2.2 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EIIBC-GUT_N PF03612.14 CDJ49345.1 - 1.9 8.2 25.8 1.1 9.0 10.2 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus CRF1 PF10380.9 CDJ49345.1 - 2.1 8.7 14.6 0.2 12.0 3.3 2.5 2 0 0 2 2 2 0 Transcription factor CRF1 Endostatin PF06482.11 CDJ49345.1 - 2.2 7.7 29.2 1.2 8.5 13.3 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin RIC3 PF15361.6 CDJ49345.1 - 2.2 8.7 19.9 4 7.8 2.3 2.4 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 UPF0565 PF10561.9 CDJ49345.1 - 2.2 7.4 15.5 4.9 6.3 8.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 U3_snoRNA_assoc PF08297.11 CDJ49345.1 - 2.3 9.0 24.9 4.2 8.2 10.4 2.4 2 0 0 2 2 2 0 U3 snoRNA associated DUF3306 PF11748.8 CDJ49345.1 - 2.5 9.0 25.3 4.6 8.1 4.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) NARP1 PF12569.8 CDJ49345.1 - 2.5 6.9 28.0 0.92 8.3 11.7 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 MDM31_MDM32 PF08118.11 CDJ49345.1 - 2.6 6.6 26.0 0.77 8.4 5.7 2.0 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins dsRBD2 PF17842.1 CDJ49345.1 - 2.6 8.2 19.9 2.5 8.3 3.6 2.3 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 DUF3408 PF11888.8 CDJ49345.1 - 2.8 8.1 34.8 0.73 10.0 16.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) RPN2_C PF18004.1 CDJ49345.1 - 2.8 7.8 29.2 3.8 7.4 13.3 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4598 PF15370.6 CDJ49345.1 - 3.4 8.2 22.5 0.66 10.5 10.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) ORC5_C PF14630.6 CDJ49345.1 - 4.2 6.8 17.7 2.7 7.4 7.3 2.3 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus Spore_coat_CotO PF14153.6 CDJ49345.1 - 4.2 7.3 39.3 0.75 9.7 8.6 2.2 2 0 0 2 2 2 0 Spore coat protein CotO DUF1764 PF08576.10 CDJ49345.1 - 4.3 8.3 29.6 2.9 8.8 13.4 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) PIP5K PF01504.18 CDJ49345.1 - 4.3 6.5 29.6 0.54 9.4 14.3 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Glyco_transf_41 PF13844.6 CDJ49345.1 - 4.5 5.6 16.0 3.9 5.8 5.9 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 41 eIF-3_zeta PF05091.12 CDJ49345.1 - 4.5 6.1 44.5 0.77 8.7 20.4 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ49345.1 - 4.6 5.0 32.6 1 7.2 6.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4199 PF13858.6 CDJ49345.1 - 4.8 7.6 19.5 3.2 8.1 7.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) HCO3_cotransp PF00955.21 CDJ49345.1 - 4.9 5.9 13.8 1.3 7.8 4.5 2.0 2 0 0 2 2 2 0 HCO3- transporter family DUF4484 PF14831.6 CDJ49345.1 - 4.9 7.1 23.9 4.1 7.4 12.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) OATP PF03137.20 CDJ49345.1 - 5 5.3 16.5 0.67 8.2 4.9 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFAP1 PF06991.11 CDJ49345.1 - 5.2 6.8 35.9 4 7.2 17.5 2.1 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing Ribosomal_L37 PF08561.10 CDJ49345.1 - 5.9 7.4 27.2 5 7.7 5.9 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Nucleoside_tran PF01733.18 CDJ49345.1 - 6 6.1 13.3 0.43 9.9 2.9 2.2 2 0 0 2 2 2 0 Nucleoside transporter DUF3464 PF11947.8 CDJ49345.1 - 6.4 6.5 32.2 0.19 11.5 4.8 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF1645 PF07816.11 CDJ49345.1 - 6.5 7.3 13.0 2.6 8.6 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Zip PF02535.22 CDJ49345.1 - 6.5 5.9 11.5 1 8.5 3.6 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter XRCC4 PF06632.12 CDJ49345.1 - 6.9 5.4 29.2 0.053 12.4 9.8 2.1 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Hydin_ADK PF17213.3 CDJ49345.1 - 7.2 6.8 22.0 8 6.7 3.3 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF5385 PF17359.2 CDJ49345.1 - 7.3 6.1 30.2 0.94 9.0 12.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5385) RPA43_OB PF17875.1 CDJ49345.1 - 7.6 7.2 20.9 2.1 9.0 9.0 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Folliculin PF11704.8 CDJ49345.1 - 8.5 6.2 28.2 4.5 7.1 13.3 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Kei1 PF08552.11 CDJ49345.1 - 8.6 6.2 18.7 9.2 6.1 9.4 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1387 PF07139.11 CDJ49345.1 - 8.9 5.9 30.4 3.4 7.3 13.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) DUF3295 PF11702.8 CDJ49345.1 - 9.2 5.5 28.0 0.63 9.3 10.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) eIF3_subunit PF08597.10 CDJ49345.1 - 9.3 6.1 35.7 0.017 15.0 11.0 2.2 2 0 0 2 2 1 0 Translation initiation factor eIF3 subunit RRP36 PF06102.12 CDJ49345.1 - 9.7 6.1 40.0 7 6.6 14.1 2.2 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 OST3_OST6 PF04756.13 CDJ49347.1 - 0.0045 16.4 0.1 0.0096 15.3 0.0 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Phenol_hyd_sub PF06099.11 CDJ49347.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Phenol hydroxylase subunit Fcf1 PF04900.12 CDJ49348.1 - 9.4e-34 115.8 2.0 9.4e-34 115.8 2.0 1.8 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CDJ49348.1 - 1.1e-14 54.8 0.1 2e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 PIN like domain PIN PF01850.21 CDJ49348.1 - 0.12 12.8 0.1 19 5.7 0.0 2.4 1 1 1 2 2 2 0 PIN domain DUF4507 PF14964.6 CDJ49348.1 - 0.15 11.0 0.4 0.31 9.9 0.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4507) YqzE PF14038.6 CDJ49348.1 - 0.55 10.3 4.7 1.1 9.3 4.7 1.5 1 0 0 1 1 1 0 YqzE-like protein SWI-SNF_Ssr4 PF08549.10 CDJ49349.1 - 0.0075 15.0 1.7 0.0084 14.8 1.7 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Zip PF02535.22 CDJ49349.1 - 0.097 11.9 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter FAM76 PF16046.5 CDJ49350.1 - 0.026 13.9 38.3 0.32 10.3 1.8 4.1 4 0 0 4 4 4 0 FAM76 protein DUF5129 PF17173.4 CDJ49350.1 - 0.84 8.7 10.9 0.051 12.7 5.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5129) CEP63 PF17045.5 CDJ49350.1 - 2.1 8.2 61.3 0.11 12.4 5.4 4.1 3 1 1 4 4 4 0 Centrosomal protein of 63 kDa HeLo PF14479.6 CDJ49351.1 - 0.041 13.7 0.2 0.12 12.1 0.2 1.8 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF1213 PF06740.12 CDJ49351.1 - 0.97 10.1 5.7 3.3 8.4 0.4 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) Flu_M1_C PF08289.11 CDJ49352.1 - 0.053 13.7 1.1 0.38 11.0 0.0 2.8 2 1 2 4 4 4 0 Influenza Matrix protein (M1) C-terminal domain JAB PF01398.21 CDJ49353.1 - 2.3e-12 47.0 0.0 4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CDJ49353.1 - 2.9e-09 37.3 0.0 4.8e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function HTH_3 PF01381.22 CDJ49353.1 - 0.017 15.2 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix Thioredoxin PF00085.20 CDJ49354.1 - 6e-30 103.3 0.0 1.4e-29 102.1 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 CDJ49354.1 - 3.3e-05 23.8 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 CDJ49354.1 - 5.2e-05 23.6 0.0 0.00026 21.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CDJ49354.1 - 0.00064 19.5 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CDJ49354.1 - 0.0061 16.5 0.0 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 CDJ49354.1 - 0.02 14.9 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 CDJ49354.1 - 0.02 15.2 0.0 0.14 12.5 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 CDJ49354.1 - 0.033 14.3 0.0 0.086 13.0 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 CDJ49354.1 - 0.035 13.5 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 CDJ49354.1 - 0.037 14.1 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain RtcB PF01139.17 CDJ49355.1 - 0.31 10.2 5.8 0.31 10.2 5.8 1.0 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB ABC2_membrane_3 PF12698.7 CDJ49355.1 - 0.66 9.0 7.0 0.64 9.1 7.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein RGS-like PF09128.11 CDJ49355.1 - 1.4 8.6 12.2 1.5 8.5 12.2 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain SRP68 PF16969.5 CDJ49355.1 - 1.9 7.4 15.3 2.1 7.2 15.3 1.0 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 Mtr2 PF10429.9 CDJ49355.1 - 3.1 7.7 8.0 4 7.4 8.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 DUF1764 PF08576.10 CDJ49355.1 - 4.4 8.3 11.0 15 6.6 11.3 1.6 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) PAT1 PF09770.9 CDJ49355.1 - 8.6 4.5 29.0 9.7 4.3 29.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IMCp PF12314.8 CDJ49356.1 - 1.9e-08 34.4 42.2 1.8e-05 24.9 18.8 2.6 1 1 1 2 2 2 2 Inner membrane complex protein RskA PF10099.9 CDJ49358.1 - 0.00023 21.5 20.5 0.00032 21.0 20.5 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ49358.1 - 0.00055 20.5 9.4 0.00081 19.9 9.4 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.6 CDJ49358.1 - 0.0016 18.6 0.4 0.0017 18.4 0.4 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Spt20 PF12090.8 CDJ49358.1 - 0.0052 16.4 21.9 0.0054 16.4 21.9 1.2 1 0 0 1 1 1 1 Spt20 family MecA PF05389.12 CDJ49358.1 - 0.0078 15.9 2.2 0.0085 15.7 2.2 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) TFIIA PF03153.13 CDJ49358.1 - 0.0078 16.3 28.3 0.0082 16.2 28.3 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4758 PF15950.5 CDJ49358.1 - 0.025 14.9 1.2 0.034 14.5 1.2 1.2 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein BAF1_ABF1 PF04684.13 CDJ49358.1 - 0.028 13.5 6.6 0.03 13.4 6.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor VIT1 PF01988.19 CDJ49358.1 - 0.046 13.6 3.3 0.057 13.3 3.3 1.2 1 0 0 1 1 1 0 VIT family DUF4179 PF13786.6 CDJ49358.1 - 0.05 14.1 2.6 0.07 13.6 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) EphA2_TM PF14575.6 CDJ49358.1 - 0.051 14.5 0.5 0.073 14.0 0.5 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2613 PF11021.8 CDJ49358.1 - 0.064 13.4 6.0 0.11 12.7 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) PMSI1 PF15322.6 CDJ49358.1 - 0.073 12.5 5.7 0.081 12.4 5.7 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative 2OG-FeII_Oxy_5 PF13759.6 CDJ49358.1 - 0.074 13.5 1.4 0.1 13.0 1.4 1.2 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Pex14_N PF04695.13 CDJ49358.1 - 0.078 13.6 17.7 0.1 13.3 17.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.12 CDJ49358.1 - 0.083 11.9 10.0 0.089 11.8 10.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) IHABP4_N PF16174.5 CDJ49358.1 - 0.087 13.4 16.9 0.1 13.2 16.9 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Suf PF05843.14 CDJ49358.1 - 0.13 12.2 10.9 0.14 12.1 10.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM60A PF15396.6 CDJ49358.1 - 0.17 11.9 3.8 0.18 11.8 3.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A R_equi_Vir PF05526.11 CDJ49358.1 - 0.21 11.5 6.0 0.22 11.3 6.0 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SpoIIP PF07454.11 CDJ49358.1 - 0.24 10.8 6.6 0.26 10.7 6.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4834 PF16118.5 CDJ49358.1 - 0.29 12.1 6.8 0.37 11.8 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Med15 PF09606.10 CDJ49358.1 - 0.33 9.6 30.6 0.36 9.5 30.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal EOS1 PF12326.8 CDJ49358.1 - 0.35 10.8 1.9 0.39 10.6 1.9 1.1 1 0 0 1 1 1 0 N-glycosylation protein CPSF100_C PF13299.6 CDJ49358.1 - 0.36 11.0 7.5 0.4 10.8 7.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CDJ49358.1 - 0.37 9.5 7.5 0.37 9.5 7.5 1.1 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 CDJ49358.1 - 0.43 10.3 7.5 0.49 10.1 7.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.17 CDJ49358.1 - 0.43 10.7 7.1 0.47 10.6 7.1 1.1 1 0 0 1 1 1 0 DDHD domain CCDC53 PF10152.9 CDJ49358.1 - 0.43 11.0 10.9 0.54 10.7 10.9 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Chorion_S16 PF05836.12 CDJ49358.1 - 0.44 10.8 9.9 0.58 10.4 9.9 1.2 1 0 0 1 1 1 0 Chorion protein S16 OATP PF03137.20 CDJ49358.1 - 0.47 8.7 1.8 0.47 8.7 1.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TERB2 PF15101.6 CDJ49358.1 - 0.52 10.3 10.4 0.51 10.3 10.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CBP_BcsG PF11658.8 CDJ49358.1 - 0.68 8.3 7.8 0.68 8.3 7.8 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF2722 PF10846.8 CDJ49358.1 - 0.7 8.8 22.9 0.86 8.5 22.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) EIIBC-GUT_N PF03612.14 CDJ49358.1 - 0.75 9.5 6.3 0.88 9.3 6.3 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus THOC2_N PF16134.5 CDJ49358.1 - 0.78 8.3 7.9 0.89 8.1 7.9 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus AIF_C PF14721.6 CDJ49358.1 - 0.79 10.1 6.4 1.1 9.7 6.4 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MDM10 PF12519.8 CDJ49358.1 - 0.86 8.4 8.1 0.92 8.3 8.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 UPF0565 PF10561.9 CDJ49358.1 - 1.1 8.3 5.5 1.3 8.1 5.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF5349 PF17298.2 CDJ49358.1 - 1.1 8.9 11.3 1.3 8.7 11.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF5521 PF17659.1 CDJ49358.1 - 1.2 6.9 6.2 1.3 6.8 6.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DUF1980 PF09323.10 CDJ49358.1 - 1.2 9.0 5.0 1.5 8.7 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) LMBR1 PF04791.16 CDJ49358.1 - 1.3 7.8 2.2 1.4 7.8 2.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FliP PF00813.20 CDJ49358.1 - 1.6 8.6 3.3 1.6 8.6 3.3 1.1 1 0 0 1 1 1 0 FliP family CLN3 PF02487.17 CDJ49358.1 - 1.8 7.5 4.1 1.9 7.5 4.1 1.1 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 CDJ49358.1 - 2.9 7.9 6.4 3.3 7.7 6.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 CDJ49358.1 - 5.7 5.5 9.5 5.8 5.5 9.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2229 PF09989.9 CDJ49358.1 - 6 6.5 7.6 7.2 6.2 7.6 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Activator_LAG-3 PF11498.8 CDJ49358.1 - 7.2 5.5 34.4 8.8 5.2 34.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 UPF0560 PF10577.9 CDJ49358.1 - 9.2 4.6 14.9 9.3 4.6 14.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SR-25 PF10500.9 CDJ49359.1 - 0.002 17.8 23.2 0.002 17.8 23.2 2.0 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ49359.1 - 0.045 13.9 32.9 0.057 13.6 32.9 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ49359.1 - 1.2 8.9 26.7 1.4 8.7 26.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 CDJ49359.1 - 2 6.5 27.1 2.2 6.3 27.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GPHR_N PF12537.8 CDJ49359.1 - 3.6 7.8 0.0 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal PPP4R2 PF09184.11 CDJ49359.1 - 3.9 7.0 16.4 5 6.6 16.4 1.1 1 0 0 1 1 1 0 PPP4R2 DUF2052 PF09747.9 CDJ49359.1 - 4.1 7.5 26.6 4.7 7.3 26.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AF-4 PF05110.13 CDJ49359.1 - 4.9 5.1 38.4 7.2 4.6 38.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Nop53 PF07767.11 CDJ49359.1 - 7 5.9 33.4 8.6 5.6 33.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PA26 PF04636.13 CDJ49359.1 - 8.1 5.2 17.8 11 4.8 17.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RRM_1 PF00076.22 CDJ49360.1 - 1.9e-17 62.9 0.1 3.6e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP_SPB PF02978.19 CDJ49360.1 - 0.0035 17.9 1.4 0.0098 16.5 1.4 1.7 1 0 0 1 1 1 1 Signal peptide binding domain TFIIA PF03153.13 CDJ49360.1 - 0.017 15.1 3.7 0.017 15.2 3.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoU_methylase PF00588.19 CDJ49362.1 - 2.4e-08 34.2 0.0 4.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family RskA PF10099.9 CDJ49364.1 - 0.21 11.9 90.8 0.024 15.0 15.8 5.8 2 2 3 5 5 5 0 Anti-sigma-K factor rskA CH_2 PF06294.11 CDJ49365.1 - 2.4e-12 46.8 0.2 3.9e-08 33.3 0.0 3.3 3 0 0 3 3 3 2 CH-like domain in sperm protein DUF5523 PF17661.1 CDJ49365.1 - 4.9 6.8 25.4 0.036 13.8 14.5 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5523) LINES_N PF14694.6 CDJ49366.1 - 0.05 13.1 0.4 0.086 12.3 0.1 1.4 2 0 0 2 2 2 0 Lines N-terminus TFB6 PF17110.5 CDJ49366.1 - 0.18 11.5 1.3 0.4 10.4 1.3 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDRT4 PF15213.6 CDJ49366.1 - 0.26 11.9 0.1 0.26 11.9 0.1 2.5 3 0 0 3 3 3 0 CMT1A duplicated region transcript 4 protein Connexin PF00029.19 CDJ49366.1 - 1.2 8.8 4.2 2 8.1 2.7 2.0 2 0 0 2 2 2 0 Connexin PPP4R2 PF09184.11 CDJ49366.1 - 2.5 7.6 7.5 0.29 10.7 2.6 1.9 2 0 0 2 2 2 0 PPP4R2 MDM31_MDM32 PF08118.11 CDJ49366.1 - 8.1 5.0 10.3 39 2.7 7.4 2.5 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF4551 PF15087.6 CDJ49367.1 - 5 5.8 31.6 6.1 5.6 31.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) LAP1C PF05609.12 CDJ49367.1 - 7.2 5.6 47.4 9 5.3 47.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Zip PF02535.22 CDJ49368.1 - 0.00084 18.7 20.8 0.0049 16.1 5.3 2.4 2 0 0 2 2 2 2 ZIP Zinc transporter Tim54 PF11711.8 CDJ49368.1 - 0.0043 15.9 12.1 0.0043 15.9 12.1 2.5 3 0 0 3 3 3 1 Inner membrane protein import complex subunit Tim54 PRCC PF10253.9 CDJ49368.1 - 0.0047 17.7 16.8 0.0047 17.7 16.8 3.3 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Utp14 PF04615.13 CDJ49368.1 - 0.11 11.1 33.6 0.3 9.6 11.5 2.1 2 0 0 2 2 2 0 Utp14 protein Apt1 PF10351.9 CDJ49368.1 - 0.13 11.0 42.0 0.094 11.6 22.9 2.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain TFIIA PF03153.13 CDJ49368.1 - 0.38 10.7 76.0 5.5 6.9 18.5 2.2 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 CDJ49368.1 - 0.64 9.4 33.1 1.8 7.9 11.4 2.2 2 0 0 2 2 2 0 SDA1 DUF2828 PF11443.8 CDJ49368.1 - 4.5 5.2 20.8 0.059 11.5 13.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DnaJ PF00226.31 CDJ49370.1 - 6.9e-15 54.9 0.0 1.9e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain DUF4383 PF14325.6 CDJ49370.1 - 0.0068 16.7 3.2 0.021 15.1 2.7 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4383) RskA PF10099.9 CDJ49370.1 - 0.084 13.2 10.6 1.4 9.1 9.4 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Sex_peptide PF08138.11 CDJ49370.1 - 1.4 9.2 3.5 1.3 9.2 0.3 2.7 3 1 0 3 3 3 0 Sex peptide (SP) family PAP_central PF04928.17 CDJ49371.1 - 3.3e-12 45.9 0.0 5e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CDJ49371.1 - 3.8e-11 42.9 1.4 2e-05 24.3 0.5 2.6 3 0 0 3 3 3 2 Poly(A) polymerase predicted RNA binding domain TraT PF05818.12 CDJ49371.1 - 0.039 13.7 7.2 5.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Spt20 PF12090.8 CDJ49371.1 - 3.7 7.1 7.6 25 4.4 8.4 1.8 2 0 0 2 2 2 0 Spt20 family MSP1_C PF07462.11 CDJ49371.1 - 3.8 6.1 13.3 0.12 11.1 7.3 1.4 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Presenilin PF01080.17 CDJ49372.1 - 0.038 12.7 40.2 0.043 12.6 40.2 1.0 1 0 0 1 1 1 0 Presenilin Radical_SAM_N PF08497.10 CDJ49372.1 - 7.9 5.6 19.0 8.9 5.5 19.0 1.0 1 0 0 1 1 1 0 Radical SAM N-terminal TFIIF_alpha PF05793.12 CDJ49373.1 - 0.0012 17.6 13.9 0.0012 17.5 13.9 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SR-25 PF10500.9 CDJ49373.1 - 0.0049 16.5 17.2 0.0061 16.2 17.2 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein UPF0492 PF15744.5 CDJ49373.1 - 0.012 14.8 12.8 0.013 14.7 12.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 DUF2992 PF11208.8 CDJ49373.1 - 0.12 12.6 13.1 0.17 12.1 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) SRP-alpha_N PF04086.13 CDJ49373.1 - 0.15 12.0 17.1 0.17 11.8 17.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Spt20 PF12090.8 CDJ49373.1 - 0.3 10.7 11.8 0.34 10.5 11.8 1.2 1 0 0 1 1 1 0 Spt20 family PBP1_TM PF14812.6 CDJ49373.1 - 0.6 10.5 12.8 0.049 14.0 8.0 1.6 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cytomega_UL84 PF06284.11 CDJ49373.1 - 0.7 8.3 6.6 0.84 8.0 6.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein FAM60A PF15396.6 CDJ49373.1 - 0.7 9.9 10.8 0.82 9.6 10.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PBP_sp32 PF07222.12 CDJ49373.1 - 0.7 9.3 10.1 0.82 9.1 10.1 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 FCP1_C PF09309.10 CDJ49373.1 - 0.75 9.6 19.5 0.92 9.3 19.5 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Zip PF02535.22 CDJ49373.1 - 0.76 8.9 7.6 0.86 8.8 7.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cellulose_synt PF03552.14 CDJ49373.1 - 0.77 8.2 3.7 0.74 8.2 3.7 1.1 1 0 0 1 1 1 0 Cellulose synthase Neur_chan_memb PF02932.16 CDJ49373.1 - 0.78 9.8 7.2 0.84 9.7 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 CDJ49373.1 - 0.83 8.4 17.4 0.95 8.2 17.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SURF2 PF05477.11 CDJ49373.1 - 0.89 9.2 12.6 1.1 8.9 12.6 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF4778 PF16008.5 CDJ49373.1 - 1.1 9.3 10.0 1.1 9.2 10.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Nucleo_P87 PF07267.11 CDJ49373.1 - 1.1 8.0 12.9 1.3 7.8 12.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Band_3_cyto PF07565.13 CDJ49373.1 - 1.1 9.0 7.0 1.2 8.9 7.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF572 PF04502.13 CDJ49373.1 - 1.1 8.8 16.3 1.3 8.6 16.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Vfa1 PF08432.10 CDJ49373.1 - 1.4 9.2 16.8 1.9 8.8 16.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 CDJ49373.1 - 1.4 7.6 17.2 1.6 7.4 17.2 1.1 1 0 0 1 1 1 0 Presenilin PPL5 PF18168.1 CDJ49373.1 - 1.5 8.1 12.8 1.8 7.8 12.8 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF4746 PF15928.5 CDJ49373.1 - 1.5 8.2 9.4 1.6 8.1 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4050 PF13259.6 CDJ49373.1 - 1.5 9.1 12.2 1.7 8.9 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) BAF1_ABF1 PF04684.13 CDJ49373.1 - 1.9 7.5 19.9 2 7.4 19.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Spore_coat_CotO PF14153.6 CDJ49373.1 - 1.9 8.4 14.5 2 8.3 14.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.17 CDJ49373.1 - 2 8.5 11.1 2.3 8.3 11.1 1.2 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 CDJ49373.1 - 2.1 7.3 10.5 2.2 7.2 10.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.6 CDJ49373.1 - 2.1 6.7 4.0 2.2 6.6 4.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 CDJ49373.1 - 2.1 6.5 14.0 2.2 6.5 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein MAJIN PF15077.6 CDJ49373.1 - 3.4 7.4 11.0 3.6 7.3 11.0 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein RR_TM4-6 PF06459.12 CDJ49373.1 - 3.7 7.3 14.4 4.3 7.1 14.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 CDJ49373.1 - 3.7 7.1 17.2 4.3 6.9 17.2 1.1 1 0 0 1 1 1 0 PPP4R2 Membralin PF09746.9 CDJ49373.1 - 5.2 6.0 5.9 5.3 6.0 5.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein V_ATPase_I PF01496.19 CDJ49373.1 - 5.5 4.8 10.5 5.8 4.7 10.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 CDJ49373.1 - 5.6 5.9 12.4 5.9 5.8 12.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 XRN_M PF17846.1 CDJ49373.1 - 6.9 5.5 13.0 8.4 5.2 13.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Sec62 PF03839.16 CDJ49373.1 - 7.7 6.0 9.2 8.9 5.7 9.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 SAPS PF04499.15 CDJ49373.1 - 9.3 4.9 17.0 10 4.7 17.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RskA PF10099.9 CDJ49374.1 - 5.5e-06 26.8 8.5 7.2e-06 26.4 8.5 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 CDJ49374.1 - 0.0034 16.5 17.3 0.0041 16.3 17.3 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ49374.1 - 0.061 13.3 27.3 0.093 12.7 27.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ49374.1 - 0.13 10.9 24.1 0.14 10.8 24.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cellulose_synt PF03552.14 CDJ49374.1 - 2.3 6.6 4.2 3 6.2 4.2 1.1 1 0 0 1 1 1 0 Cellulose synthase Utp14 PF04615.13 CDJ49374.1 - 5.5 5.4 23.4 6 5.3 23.4 1.0 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 CDJ49374.1 - 6.9 3.6 29.6 8.2 3.4 29.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ATP_sub_h PF10775.9 CDJ49376.1 - 0.16 12.0 0.2 4.1 7.5 0.2 2.9 2 0 0 2 2 2 0 ATP synthase complex subunit h Myb_DNA-binding PF00249.31 CDJ49377.1 - 1.6e-09 37.8 0.5 2.8e-09 37.0 0.5 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ49377.1 - 3.7e-06 27.1 0.5 1.1e-05 25.6 0.5 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Fasciclin PF02469.22 CDJ49378.1 - 4.8e-06 26.8 0.0 1.5e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Fasciclin domain Notch PF00066.17 CDJ49380.1 - 1.8e-43 146.7 108.4 1.1e-08 35.4 12.4 6.3 6 0 0 6 6 6 6 LNR domain DUF4949 PF16307.5 CDJ49380.1 - 0.0075 16.4 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4949) Auts2 PF15336.6 CDJ49381.1 - 8.9 6.4 14.4 0.24 11.5 7.4 1.8 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein Mog1 PF04603.12 CDJ49382.1 - 4.9e-30 104.7 0.0 6.7e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DUF3537 PF12056.8 CDJ49383.1 - 0.084 11.7 1.1 0.1 11.4 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DUF4872 PF16169.5 CDJ49383.1 - 0.089 12.6 2.8 0.11 12.3 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4872) NOA36 PF06524.12 CDJ49383.1 - 4.9 6.4 8.1 5.6 6.2 8.1 1.1 1 0 0 1 1 1 0 NOA36 protein ANAPC15 PF15243.6 CDJ49383.1 - 5.6 7.4 15.6 29 5.2 15.6 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 Vfa1 PF08432.10 CDJ49383.1 - 6.4 7.1 9.4 7.6 6.8 9.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ubiquitin PF00240.23 CDJ49384.1 - 1.2e-11 44.2 0.5 2.9e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_4 PF18036.1 CDJ49384.1 - 0.00012 22.1 1.4 0.17 11.9 0.1 3.5 2 2 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD PF11976.8 CDJ49384.1 - 0.0028 17.4 1.2 0.0066 16.2 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IMCp PF12314.8 CDJ49385.1 - 9.4e-27 93.1 51.9 7.3e-26 90.3 22.4 3.3 1 1 2 3 3 3 3 Inner membrane complex protein VPS11_C PF12451.8 CDJ49386.1 - 4.6e-05 23.5 0.1 0.00011 22.4 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 CDJ49386.1 - 0.0039 17.2 4.2 0.013 15.5 4.2 2.0 1 0 0 1 1 1 1 Zinc-finger Vps39_2 PF10367.9 CDJ49386.1 - 0.0061 17.0 0.4 0.017 15.6 0.4 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 CDJ49386.1 - 0.012 15.5 1.5 0.012 15.5 1.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CDJ49386.1 - 0.026 14.4 1.4 0.087 12.7 1.4 1.9 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 CDJ49386.1 - 0.044 13.7 6.4 0.16 12.0 6.4 2.0 1 0 0 1 1 1 0 zinc-RING finger domain Bacillus_HBL PF05791.11 CDJ49386.1 - 0.082 12.7 0.5 0.13 12.0 0.5 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) zf-C3HC4 PF00097.25 CDJ49386.1 - 0.19 11.6 5.9 0.67 9.9 5.9 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-TFIIIC PF12660.7 CDJ49386.1 - 0.33 10.9 2.7 2.1 8.3 1.4 2.7 2 1 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex zf-RING_UBOX PF13445.6 CDJ49386.1 - 2.1 8.4 5.1 0.49 10.5 1.3 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 CDJ49386.1 - 4.4 7.7 12.3 0.42 11.0 0.9 3.5 3 0 0 3 3 3 0 RING-H2 zinc finger domain AsnA PF03590.15 CDJ49387.1 - 3.5e-85 285.4 0.0 4.3e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 Aspartate-ammonia ligase CLZ PF16526.5 CDJ49387.1 - 0.0053 17.1 0.1 0.013 15.8 0.1 1.6 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ribosomal_L24e PF01246.20 CDJ49388.1 - 1.5e-25 89.2 0.6 1.5e-25 89.2 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 CDJ49388.1 - 0.059 12.9 0.3 0.07 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Pam16 PF03656.13 CDJ49389.1 - 1.7e-08 34.6 13.8 4e-06 26.9 11.2 2.7 1 1 1 2 2 2 1 Pam16 Cwf_Cwc_15 PF04889.12 CDJ49389.1 - 0.13 12.0 1.7 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Apt1 PF10351.9 CDJ49389.1 - 0.18 10.6 5.5 0.18 10.6 5.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AF-4 PF05110.13 CDJ49389.1 - 0.68 7.9 13.9 0.67 8.0 13.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MAP70 PF07058.11 CDJ49389.1 - 1.4 7.6 8.8 1.7 7.3 8.8 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 Med15 PF09606.10 CDJ49390.1 - 0.00021 20.1 19.9 0.00024 19.9 19.9 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal K_channel_TID PF07941.11 CDJ49390.1 - 0.0013 19.2 10.1 0.0013 19.2 10.1 2.9 2 1 0 2 2 1 1 Potassium channel Kv1.4 tandem inactivation domain SprA-related PF12118.8 CDJ49390.1 - 0.0051 16.0 16.2 0.0068 15.6 16.2 1.1 1 0 0 1 1 1 1 SprA-related family SpoIIP PF07454.11 CDJ49390.1 - 0.014 14.9 1.2 0.014 14.9 1.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 CDJ49390.1 - 0.02 14.9 25.0 0.028 14.4 25.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ49390.1 - 0.022 12.7 2.2 0.025 12.5 2.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4471 PF14740.6 CDJ49390.1 - 0.032 13.5 1.3 0.038 13.2 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DDRGK PF09756.9 CDJ49390.1 - 0.069 12.7 9.7 0.095 12.3 9.7 1.3 1 0 0 1 1 1 0 DDRGK domain FAM60A PF15396.6 CDJ49390.1 - 0.15 12.1 2.3 0.18 11.8 2.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SKA1 PF07160.12 CDJ49390.1 - 0.31 10.9 12.7 0.4 10.5 12.7 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CLN3 PF02487.17 CDJ49390.1 - 0.33 10.0 1.0 0.36 9.8 1.0 1.2 1 0 0 1 1 1 0 CLN3 protein DUF4518 PF15008.6 CDJ49390.1 - 0.42 9.7 7.7 0.68 9.1 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Presenilin PF01080.17 CDJ49390.1 - 0.74 8.5 9.5 0.91 8.2 9.5 1.1 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 CDJ49390.1 - 1 7.8 12.5 1.2 7.5 12.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Neur_chan_memb PF02932.16 CDJ49390.1 - 1.5 8.8 4.0 1.8 8.6 4.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAE2 PF08573.10 CDJ49390.1 - 2.1 9.5 14.8 0.97 10.6 10.0 2.0 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus FAM70 PF14967.6 CDJ49390.1 - 2.4 7.6 8.7 3.2 7.1 8.7 1.3 1 0 0 1 1 1 0 FAM70 protein DUF4407 PF14362.6 CDJ49390.1 - 2.5 7.4 12.1 3.7 6.8 12.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4355 PF14265.6 CDJ49390.1 - 6.6 7.0 17.8 16 5.7 17.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) TFIIA PF03153.13 CDJ49391.1 - 8.7 6.2 76.5 11 5.9 76.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BMFP PF04380.13 CDJ49392.1 - 0.069 13.6 1.2 0.72 10.4 0.3 2.2 2 1 0 2 2 2 0 Membrane fusogenic activity DUF4010 PF13194.6 CDJ49393.1 - 0.00097 18.9 6.2 0.0016 18.2 4.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4010) SCAI PF12070.8 CDJ49393.1 - 0.77 8.6 5.5 0.83 8.4 5.5 1.1 1 0 0 1 1 1 0 Protein SCAI Trp_oprn_chp PF09534.10 CDJ49393.1 - 0.97 9.2 30.0 1.3 8.8 29.6 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NUDE_C PF04880.13 CDJ49393.1 - 6.1 7.3 11.9 11 6.5 11.9 1.4 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region PAN_1 PF00024.26 CDJ49395.1 - 5.1e-56 186.6 81.0 1.5e-06 28.1 1.4 11.8 5 4 7 12 12 12 11 PAN domain PAN_4 PF14295.6 CDJ49395.1 - 2.8e-42 142.4 76.1 2.5e-07 30.5 0.3 12.2 11 2 1 12 12 12 11 PAN domain PAN_2 PF08276.11 CDJ49395.1 - 0.0012 19.0 82.4 0.46 10.6 0.5 11.4 10 1 0 11 11 11 6 PAN-like domain PAN_3 PF08277.12 CDJ49395.1 - 0.021 14.6 0.1 0.021 14.6 0.1 9.8 11 0 0 11 11 11 0 PAN-like domain Pox_L3_FP4 PF03339.14 CDJ49395.1 - 0.041 12.9 0.1 0.072 12.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein Defb50 PF17546.2 CDJ49395.1 - 3 7.8 6.8 50 3.9 0.1 3.9 3 0 0 3 3 3 0 Beta defensin 50 Presenilin PF01080.17 CDJ49396.1 - 0.055 12.2 2.5 0.11 11.3 2.5 1.4 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ49396.1 - 0.057 13.0 29.1 1.7 8.2 0.0 3.3 3 0 0 3 3 3 0 Spt20 family RAP1 PF07218.11 CDJ49396.1 - 0.06 11.6 4.0 0.088 11.1 4.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 CDJ49396.1 - 1.4 7.4 21.7 0.0072 14.9 12.9 1.5 2 0 0 2 2 2 0 Macoilin family SmpB PF01668.18 CDJ49396.1 - 2.8 7.8 6.4 1.7 8.5 3.6 1.9 2 0 0 2 2 2 0 SmpB protein DUF4171 PF13775.6 CDJ49396.1 - 8.8 6.8 20.1 0.83 10.1 14.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4171) DUF2722 PF10846.8 CDJ49397.1 - 0.0037 16.3 14.3 0.0037 16.3 14.3 7.9 4 1 1 5 5 5 2 Protein of unknown function (DUF2722) BUD22 PF09073.10 CDJ49397.1 - 0.0063 15.9 0.1 0.0063 15.9 0.1 4.6 2 2 2 4 4 4 2 BUD22 COX6B PF02297.17 CDJ49398.1 - 0.32 11.3 5.9 0.68 10.2 3.2 2.4 2 1 1 3 3 3 0 Cytochrome oxidase c subunit VIb PHD PF00628.29 CDJ49398.1 - 0.51 10.3 3.1 2.6 8.0 0.1 2.6 3 0 0 3 3 3 0 PHD-finger NDUF_B7 PF05676.13 CDJ49398.1 - 0.99 9.2 4.6 1.5 8.6 0.3 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 CDJ49398.1 - 3.7 7.6 8.8 19 5.4 0.1 4.0 4 0 0 4 4 4 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, zf-C3HC4_2 PF13923.6 CDJ49399.1 - 9.2e-10 38.2 10.7 9.2e-10 38.2 10.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ49399.1 - 1.7e-07 31.5 9.6 1.7e-07 31.5 9.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ49399.1 - 5.7e-07 29.3 10.0 5.7e-07 29.3 10.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ49399.1 - 8.8e-07 28.9 10.6 8.8e-07 28.9 10.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDJ49399.1 - 1.2e-06 28.3 10.2 1.2e-06 28.3 10.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 CDJ49399.1 - 1.1e-05 25.5 0.8 2.5e-05 24.3 0.8 1.6 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.6 CDJ49399.1 - 2.9e-05 24.1 12.0 2.9e-05 24.1 12.0 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDJ49399.1 - 3.2e-05 23.8 7.0 3.2e-05 23.8 7.0 2.5 3 1 0 3 3 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CDJ49399.1 - 0.0074 16.6 8.2 0.0074 16.6 8.2 2.7 3 2 1 4 4 1 1 RING-H2 zinc finger domain TFIIA PF03153.13 CDJ49399.1 - 0.0083 16.2 33.6 0.0083 16.2 33.6 3.1 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ49399.1 - 0.0094 15.6 21.5 0.16 11.5 0.7 2.3 2 0 0 2 2 2 2 Exonuclease VII, large subunit K_channel_TID PF07941.11 CDJ49399.1 - 0.011 16.1 19.2 0.011 16.1 19.2 8.0 4 2 1 7 7 1 0 Potassium channel Kv1.4 tandem inactivation domain zf-RING_10 PF16685.5 CDJ49399.1 - 0.019 15.1 8.5 0.053 13.7 8.5 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 EPL1 PF10513.9 CDJ49399.1 - 0.054 13.9 14.8 1.3 9.4 9.5 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Prok-RING_4 PF14447.6 CDJ49399.1 - 0.12 12.2 16.9 0.027 14.3 10.9 2.6 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 SR-25 PF10500.9 CDJ49399.1 - 0.23 11.1 22.7 0.79 9.3 6.4 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein LON_substr_bdg PF02190.16 CDJ49399.1 - 1.6 8.6 0.0 1.6 8.6 0.0 3.1 1 1 1 3 3 2 0 ATP-dependent protease La (LON) substrate-binding domain Membralin PF09746.9 CDJ49399.1 - 2.4 7.1 6.9 5.9 5.8 4.0 2.0 2 0 0 2 2 2 0 Tumour-associated protein SID-1_RNA_chan PF13965.6 CDJ49399.1 - 2.8 6.2 5.8 0.18 10.2 0.9 1.4 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 zf-RING_6 PF14835.6 CDJ49399.1 - 3 7.8 6.9 8.1 6.4 6.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CDJ49399.1 - 3.8 7.4 13.0 0.036 13.8 3.9 2.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain PDDEXK_6 PF04720.12 CDJ49399.1 - 7.3 6.5 17.2 3.2 7.6 1.1 2.3 2 0 0 2 2 2 0 PDDEXK-like family of unknown function FAM60A PF15396.6 CDJ49399.1 - 9.8 6.1 13.9 3.8 7.5 6.1 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Tfb4 PF03850.14 CDJ49399.1 - 9.8 5.6 15.9 8.3 5.8 3.3 2.3 2 0 0 2 2 2 0 Transcription factor Tfb4 RskA PF10099.9 CDJ49400.1 - 2e-05 25.0 9.6 2e-05 25.0 9.6 2.0 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ49400.1 - 0.0032 17.1 14.8 0.0033 17.1 5.6 2.2 2 0 0 2 2 2 2 Spt20 family Cwf_Cwc_15 PF04889.12 CDJ49400.1 - 0.025 14.3 5.4 0.27 10.9 5.4 1.9 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Gtr1_RagA PF04670.12 CDJ49400.1 - 0.032 13.6 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RNR_inhib PF08591.10 CDJ49400.1 - 0.033 15.5 0.7 0.033 15.5 0.7 2.1 2 1 0 2 2 2 0 Ribonucleotide reductase inhibitor DUF3138 PF11336.8 CDJ49400.1 - 0.76 8.3 11.4 1.2 7.7 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DLIC PF05783.11 CDJ49400.1 - 0.78 8.5 6.1 0.9 8.3 6.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) CDC37_N PF03234.14 CDJ49400.1 - 2 9.3 8.3 12 6.9 3.6 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding IMUP PF15761.5 CDJ49400.1 - 3.9 8.2 12.9 0.13 13.0 5.0 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein CCDC53 PF10152.9 CDJ49400.1 - 6.7 7.1 9.4 14 6.1 0.4 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SR-25 PF10500.9 CDJ49401.1 - 0.0056 16.3 29.9 0.0056 16.3 29.9 6.1 4 1 1 6 6 6 3 Nuclear RNA-splicing-associated protein DUF4252 PF14060.6 CDJ49401.1 - 0.32 10.9 4.1 0.22 11.4 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) ACOX PF01756.19 CDJ49402.1 - 1.3e-12 47.6 25.1 2.6e-08 33.7 21.2 3.4 1 1 1 2 2 2 2 Acyl-CoA oxidase MDFI PF15316.6 CDJ49402.1 - 3.6e-05 23.9 17.5 4.8e-05 23.5 17.5 1.2 1 0 0 1 1 1 1 MyoD family inhibitor Presenilin PF01080.17 CDJ49402.1 - 5.8e-05 22.0 24.7 6.8e-05 21.8 24.7 1.1 1 0 0 1 1 1 1 Presenilin DUF4045 PF13254.6 CDJ49402.1 - 0.0011 18.8 17.0 0.0012 18.5 17.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) PAT1 PF09770.9 CDJ49402.1 - 0.0022 16.4 41.2 0.0025 16.2 41.2 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 VIR_N PF15912.5 CDJ49402.1 - 0.004 16.8 10.5 0.0045 16.6 10.5 1.1 1 0 0 1 1 1 1 Virilizer, N-terminal TFIIA PF03153.13 CDJ49402.1 - 0.004 17.2 59.2 0.0067 16.5 59.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Dapper PF15268.6 CDJ49402.1 - 0.0057 15.6 26.9 0.0066 15.4 26.9 1.0 1 0 0 1 1 1 1 Dapper FNIP_N PF14636.6 CDJ49402.1 - 0.0074 17.3 19.0 0.011 16.8 19.0 1.2 1 0 0 1 1 1 1 Folliculin-interacting protein N-terminus NPR3 PF03666.13 CDJ49402.1 - 0.0088 14.9 21.9 0.011 14.6 21.9 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 LAP1C PF05609.12 CDJ49402.1 - 0.01 14.9 24.4 0.012 14.7 24.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 CDJ49402.1 - 0.011 12.9 21.0 0.011 12.9 21.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SPX PF03105.19 CDJ49402.1 - 0.012 15.6 16.8 0.013 15.4 16.8 1.1 1 0 0 1 1 1 0 SPX domain Smg8_Smg9 PF10220.9 CDJ49402.1 - 0.012 13.9 18.9 0.014 13.7 18.9 1.0 1 0 0 1 1 1 0 Smg8_Smg9 SAPS PF04499.15 CDJ49402.1 - 0.014 14.2 15.3 0.016 14.0 15.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.6 CDJ49402.1 - 0.017 13.9 16.3 0.019 13.7 16.3 1.1 1 0 0 1 1 1 0 Raftlin Ndc1_Nup PF09531.10 CDJ49402.1 - 0.022 13.5 24.9 0.028 13.1 24.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LMBR1 PF04791.16 CDJ49402.1 - 0.022 13.7 11.8 0.026 13.5 11.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CAC1F_C PF16885.5 CDJ49402.1 - 0.025 14.3 15.2 0.03 14.0 15.2 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Exonuc_VII_L PF02601.15 CDJ49402.1 - 0.027 14.0 28.5 0.034 13.7 28.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Suf PF05843.14 CDJ49402.1 - 0.028 14.4 30.3 0.046 13.7 30.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hamartin PF04388.12 CDJ49402.1 - 0.029 13.0 20.5 0.033 12.9 20.5 1.1 1 0 0 1 1 1 0 Hamartin protein SLC12 PF03522.15 CDJ49402.1 - 0.033 13.2 28.2 0.043 12.9 28.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ49402.1 - 0.033 13.7 28.2 0.041 13.4 28.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist WTX PF09422.10 CDJ49402.1 - 0.037 13.1 18.7 0.048 12.8 18.7 1.1 1 0 0 1 1 1 0 WTX protein AF-4 PF05110.13 CDJ49402.1 - 0.05 11.7 28.5 0.058 11.5 28.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RIFIN PF02009.16 CDJ49402.1 - 0.066 13.1 16.0 0.088 12.7 16.0 1.1 1 0 0 1 1 1 0 Rifin HCO3_cotransp PF00955.21 CDJ49402.1 - 0.072 11.9 8.3 0.092 11.6 8.3 1.1 1 0 0 1 1 1 0 HCO3- transporter family Hid1 PF12722.7 CDJ49402.1 - 0.092 10.9 23.7 0.11 10.6 23.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1387 PF07139.11 CDJ49402.1 - 0.096 12.4 23.5 0.12 12.0 23.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) RR_TM4-6 PF06459.12 CDJ49402.1 - 0.13 12.1 28.1 0.17 11.7 28.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S64 PF08192.11 CDJ49402.1 - 0.18 10.3 18.8 0.21 10.1 18.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 FAM60A PF15396.6 CDJ49402.1 - 0.21 11.6 22.7 0.28 11.1 22.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CDK5_activator PF03261.15 CDJ49402.1 - 0.22 11.0 22.5 0.29 10.6 22.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Dicty_REP PF05086.12 CDJ49402.1 - 0.24 9.4 12.1 0.25 9.3 12.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zip PF02535.22 CDJ49402.1 - 0.24 10.6 19.6 0.37 10.0 19.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 CDJ49402.1 - 0.24 9.6 25.3 0.31 9.3 25.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Sin_N PF04801.13 CDJ49402.1 - 0.25 10.5 36.2 0.29 10.3 36.2 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region ALMT PF11744.8 CDJ49402.1 - 0.3 9.9 21.9 0.38 9.5 21.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Macoilin PF09726.9 CDJ49402.1 - 0.34 9.4 20.0 0.41 9.1 20.0 1.1 1 0 0 1 1 1 0 Macoilin family Paramyxo_ncap PF00973.19 CDJ49402.1 - 0.37 9.7 17.9 0.44 9.4 17.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3295 PF11702.8 CDJ49402.1 - 0.42 9.9 25.8 0.56 9.5 25.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Velvet PF11754.8 CDJ49402.1 - 0.63 9.9 25.6 1.1 9.2 25.6 1.4 1 0 0 1 1 1 0 Velvet factor Membralin PF09746.9 CDJ49402.1 - 0.69 8.9 16.1 0.82 8.6 16.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein Pkinase_fungal PF17667.1 CDJ49402.1 - 0.8 8.4 16.6 1 8.1 16.6 1.1 1 0 0 1 1 1 0 Fungal protein kinase Peroxin-13_N PF04088.13 CDJ49402.1 - 0.8 10.0 24.9 0.48 10.7 8.6 2.6 2 1 1 3 3 2 0 Peroxin 13, N-terminal region TCP PF03634.13 CDJ49402.1 - 0.87 10.1 26.3 1.4 9.5 26.3 1.4 1 0 0 1 1 1 0 TCP family transcription factor AAA_11 PF13086.6 CDJ49402.1 - 0.96 9.2 26.1 1.3 8.7 26.1 1.2 1 0 0 1 1 1 0 AAA domain SID-1_RNA_chan PF13965.6 CDJ49402.1 - 1 7.7 12.1 1.5 7.1 12.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spore_coat_CotO PF14153.6 CDJ49402.1 - 1.2 9.0 38.3 2.3 8.1 38.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DUF2052 PF09747.9 CDJ49402.1 - 1.3 9.2 30.3 1.7 8.7 30.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DcuA_DcuB PF03605.14 CDJ49402.1 - 1.4 7.7 16.5 0.091 11.6 2.7 2.4 1 1 1 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter Hydin_ADK PF17213.3 CDJ49402.1 - 1.4 9.2 20.2 2.3 8.4 20.2 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain BORG_CEP PF14957.6 CDJ49402.1 - 1.8 9.7 20.3 3.3 8.9 20.3 1.4 1 0 0 1 1 1 0 Cdc42 effector SRP-alpha_N PF04086.13 CDJ49402.1 - 2 8.3 29.4 2 8.3 27.3 1.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Rtf2 PF04641.12 CDJ49402.1 - 2.1 7.7 23.5 2.8 7.2 23.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Mem_trans PF03547.18 CDJ49402.1 - 2.1 6.6 9.1 2.8 6.2 9.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Neur_chan_memb PF02932.16 CDJ49402.1 - 2.3 8.2 26.4 3.3 7.7 26.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region XRN_M PF17846.1 CDJ49402.1 - 2.6 6.9 23.0 3.4 6.5 23.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain CAML PF14963.6 CDJ49402.1 - 3.3 7.8 10.9 4.3 7.4 10.9 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand PPP4R2 PF09184.11 CDJ49402.1 - 4.1 6.9 17.9 5.3 6.5 17.9 1.1 1 0 0 1 1 1 0 PPP4R2 DUF4746 PF15928.5 CDJ49402.1 - 4.1 6.7 24.3 5.8 6.2 24.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Endostatin PF06482.11 CDJ49402.1 - 4.3 6.7 28.4 6 6.2 28.4 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Med15 PF09606.10 CDJ49402.1 - 4.5 5.8 59.4 6.1 5.4 59.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SKA1 PF07160.12 CDJ49402.1 - 7.3 6.4 32.8 9.8 5.9 32.8 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 AUX_IAA PF02309.16 CDJ49402.1 - 9.4 6.0 19.9 14 5.5 19.9 1.3 1 0 0 1 1 1 0 AUX/IAA family Ac76 PF05814.11 CDJ49403.1 - 0.099 12.7 0.2 0.25 11.4 0.2 1.7 1 0 0 1 1 1 0 Orf76 (Ac76) HMMR_N PF15905.5 CDJ49404.1 - 0.42 10.1 2.0 0.65 9.4 2.0 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal AAA_lid_4 PF17864.1 CDJ49404.1 - 0.49 10.2 2.8 6 6.7 0.7 2.6 2 0 0 2 2 2 0 RuvB AAA lid domain HEAT PF02985.22 CDJ49404.1 - 1.9 9.0 6.4 62 4.3 0.0 5.3 6 0 0 6 6 6 0 HEAT repeat ANAPC4_WD40 PF12894.7 CDJ49405.1 - 8.9e-05 22.7 0.0 0.031 14.6 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CDJ49405.1 - 0.015 14.4 0.1 0.077 12.0 0.2 1.9 2 0 0 2 2 2 0 Coatomer WD associated region TPH PF13868.6 CDJ49406.1 - 1.1e-11 43.8 141.6 1.1e-11 43.8 141.6 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Cnd1 PF12717.7 CDJ49407.1 - 0.027 14.5 6.7 0.58 10.2 0.6 3.9 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CDJ49407.1 - 0.054 13.1 6.7 0.98 8.9 0.2 3.8 3 1 1 4 4 4 0 CLASP N terminal WRW PF10206.9 CDJ49407.1 - 0.15 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f HEAT_2 PF13646.6 CDJ49407.1 - 1.8 9.0 25.5 0.51 10.8 5.5 5.4 5 1 0 5 5 5 0 HEAT repeats HEAT_EZ PF13513.6 CDJ49407.1 - 6.2 7.4 24.2 31 5.2 0.4 7.0 6 0 0 6 6 6 0 HEAT-like repeat WD40 PF00400.32 CDJ49409.1 - 2.5e-07 31.2 0.7 0.00062 20.5 0.1 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat FAP206 PF12018.8 CDJ49410.1 - 8.3e-07 28.8 0.1 0.1 12.1 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function YHS PF04945.13 CDJ49410.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 YHS domain Transketolase_N PF00456.21 CDJ49411.1 - 4.9e-143 476.1 0.0 8e-143 475.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CDJ49411.1 - 7.8e-37 126.7 0.0 1.2e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 CDJ49411.1 - 0.00037 19.8 0.0 0.00066 19.0 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 CDJ49411.1 - 0.0053 16.6 0.0 0.028 14.3 0.0 2.2 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.20 CDJ49411.1 - 0.022 13.7 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component MBF1 PF08523.10 CDJ49412.1 - 4.3e-19 68.7 1.3 4.3e-19 68.7 1.3 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CDJ49412.1 - 8.4e-15 54.6 0.1 1.3e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 CDJ49412.1 - 8e-07 29.0 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 CDJ49412.1 - 8e-07 29.3 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 CDJ49412.1 - 0.00028 21.3 0.0 0.00049 20.5 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 CDJ49412.1 - 0.013 15.4 0.1 0.026 14.5 0.1 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 CDJ49412.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_25 PF13413.6 CDJ49412.1 - 0.04 13.8 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5134 PF17197.4 CDJ49413.1 - 0.11 12.4 8.5 0.22 11.4 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) ArnB_C PF18677.1 CDJ49413.1 - 0.14 12.2 0.0 0.45 10.7 0.0 1.8 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain Dynein_light PF01221.18 CDJ49414.1 - 1.5e-41 140.6 0.4 1.6e-41 140.5 0.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 XRN_M PF17846.1 CDJ49416.1 - 0.0083 15.1 1.6 0.0083 15.1 1.6 2.1 2 0 0 2 2 2 1 Xrn1 helical domain SAWADEE PF16719.5 CDJ49416.1 - 0.01 15.8 0.2 0.061 13.3 0.0 2.4 3 0 0 3 3 3 0 SAWADEE domain F-112 PF09645.10 CDJ49416.1 - 0.036 14.2 1.6 0.036 14.2 1.6 2.2 2 1 1 3 3 3 0 F-112 protein Gti1_Pac2 PF09729.9 CDJ49416.1 - 0.064 13.4 6.4 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family DDHD PF02862.17 CDJ49416.1 - 0.42 10.7 8.9 0.8 9.8 2.4 2.1 2 0 0 2 2 2 0 DDHD domain zf-CpG_bind_C PF12269.8 CDJ49416.1 - 3.2 7.5 11.1 2.7 7.7 0.4 2.3 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF4813 PF16072.5 CDJ49416.1 - 7.4 6.2 23.3 12 5.5 23.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF572 PF04502.13 CDJ49416.1 - 9.3 5.8 17.7 5.1 6.6 9.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) V_ATPase_I PF01496.19 CDJ49416.1 - 9.3 4.0 10.7 5 4.9 4.5 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF5320 PF17253.2 CDJ49417.1 - 0.0058 17.7 6.0 0.0099 16.9 6.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5320) Pro_CA PF00484.19 CDJ49417.1 - 0.31 11.3 3.4 0.41 10.9 3.4 1.1 1 0 0 1 1 1 0 Carbonic anhydrase AAA_23 PF13476.6 CDJ49417.1 - 0.46 11.0 9.3 0.47 10.9 9.3 1.1 1 0 0 1 1 1 0 AAA domain DUF4192 PF13830.6 CDJ49417.1 - 0.96 9.4 12.2 1.1 9.2 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF4407 PF14362.6 CDJ49417.1 - 1.3 8.3 11.5 1.7 7.9 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ49417.1 - 1.8 8.4 25.9 2.2 8.2 25.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ49417.1 - 8.4 7.0 19.0 12 6.6 19.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SprA-related PF12118.8 CDJ49418.1 - 5.2 6.1 23.6 6.7 5.8 23.6 1.1 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.13 CDJ49418.1 - 9.5 6.1 18.2 12 5.8 18.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_1 PF00515.28 CDJ49419.1 - 6.8e-66 215.6 32.2 1.1e-08 34.6 0.0 9.3 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ49419.1 - 2.3e-57 186.5 27.1 1.8e-06 27.6 0.4 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ49419.1 - 3.2e-37 125.9 14.5 5.7e-07 29.1 1.1 8.6 5 2 3 8 8 8 7 TPR repeat TPR_8 PF13181.6 CDJ49419.1 - 3.9e-33 110.9 25.5 0.00018 21.4 0.0 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ49419.1 - 4.5e-28 97.6 11.9 3.5e-05 24.4 0.3 6.8 4 3 2 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ49419.1 - 2.8e-27 93.1 9.3 0.0017 19.0 0.3 9.8 5 3 5 10 10 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ49419.1 - 3.1e-27 94.7 12.5 1.1e-12 48.1 0.5 7.0 3 3 2 5 5 5 5 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ49419.1 - 1.9e-24 85.6 0.3 5.5e-06 26.4 0.0 6.6 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ49419.1 - 5e-24 82.5 7.5 0.00013 21.7 0.1 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ49419.1 - 2.5e-23 82.3 14.8 4.2e-05 24.0 0.8 7.5 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ49419.1 - 4.1e-21 73.8 12.1 0.0036 17.6 0.6 8.1 7 0 0 7 7 7 4 Tetratricopeptide repeat STI1 PF17830.1 CDJ49419.1 - 4.4e-21 74.6 6.5 7.5e-14 51.4 4.0 3.1 2 0 0 2 2 2 2 STI1 domain TPR_10 PF13374.6 CDJ49419.1 - 4e-18 64.7 13.3 0.22 11.5 0.0 8.7 9 0 0 9 9 8 5 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ49419.1 - 3.8e-10 39.7 15.5 0.23 11.5 0.0 7.8 6 2 1 7 7 7 3 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 CDJ49419.1 - 2.8e-07 30.7 19.1 0.81 10.5 0.2 8.7 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ49419.1 - 1.1e-05 25.5 15.5 0.052 13.8 1.5 4.9 3 3 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 CDJ49419.1 - 3.6e-05 23.6 16.9 0.033 13.9 0.7 4.9 2 2 2 4 4 4 3 Tetratricopeptide repeat-like domain DUF3856 PF12968.7 CDJ49419.1 - 0.00051 20.1 8.2 0.95 9.5 1.1 4.7 3 3 1 4 4 4 2 Domain of Unknown Function (DUF3856) ChAPs PF09295.10 CDJ49419.1 - 0.0015 17.6 4.4 1.1 8.2 1.5 3.0 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 CDJ49419.1 - 0.0017 18.6 6.4 0.7 10.3 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.8 CDJ49419.1 - 0.0028 16.6 1.3 0.052 12.5 0.1 5.0 2 1 3 5 5 5 2 NMDA receptor-regulated protein 1 RPN7 PF10602.9 CDJ49419.1 - 0.055 13.2 18.1 0.48 10.1 3.6 5.2 3 2 2 5 5 5 0 26S proteasome subunit RPN7 PPR PF01535.20 CDJ49419.1 - 0.17 12.2 0.3 0.17 12.2 0.3 5.3 7 0 0 7 7 4 0 PPR repeat DnaI_N PF07319.11 CDJ49419.1 - 0.57 10.9 10.8 0.083 13.6 1.0 3.9 4 1 0 4 4 4 0 Primosomal protein DnaI N-terminus MAS20 PF02064.15 CDJ49419.1 - 0.95 9.6 0.0 0.95 9.6 0.0 4.6 5 1 1 6 6 6 0 MAS20 protein import receptor TBCA PF02970.16 CDJ49419.1 - 3.5 8.0 12.2 0.27 11.6 3.3 3.6 2 1 2 4 4 4 0 Tubulin binding cofactor A ACDC PF14733.6 CDJ49420.1 - 1.3e-20 73.5 3.8 4.1e-20 71.9 3.8 1.9 1 0 0 1 1 1 1 AP2-coincident C-terminal CD20 PF04103.15 CDJ49420.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.1 1 1 1 2 2 2 0 CD20-like family NPR3 PF03666.13 CDJ49420.1 - 0.15 10.8 14.8 0.44 9.3 0.1 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Med15 PF09606.10 CDJ49420.1 - 5.9 5.4 56.0 8.1 5.0 56.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TraT PF05818.12 CDJ49421.1 - 0.92 9.1 8.8 1.1 8.9 8.8 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein SAP130_C PF16014.5 CDJ49421.1 - 2.7 7.0 6.4 2.7 7.0 6.4 1.0 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus MSP1_C PF07462.11 CDJ49421.1 - 8 5.0 6.8 8.9 4.9 6.8 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus GWT1 PF06423.12 CDJ49423.1 - 0.057 13.5 0.7 0.087 12.9 0.7 1.4 1 1 0 1 1 1 0 GWT1 CD20 PF04103.15 CDJ49423.1 - 0.14 12.3 2.4 0.3 11.2 0.1 2.1 1 1 1 2 2 2 0 CD20-like family DUF3357 PF11837.8 CDJ49423.1 - 1.5 9.3 9.0 1.8 9.1 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Sin_N PF04801.13 CDJ49423.1 - 2.9 7.0 26.6 4 6.5 26.6 1.3 1 1 0 1 1 1 0 Sin-like protein conserved region DUF3123 PF11321.8 CDJ49423.1 - 3.5 8.3 8.6 0.66 10.7 4.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) DUF2371 PF10177.9 CDJ49423.1 - 3.9 7.6 8.9 0.16 12.1 0.8 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF1345 PF07077.11 CDJ49423.1 - 5.2 6.8 5.9 4.2 7.0 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) Hid1 PF12722.7 CDJ49423.1 - 6.5 4.7 17.3 7 4.6 17.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Trp_oprn_chp PF09534.10 CDJ49423.1 - 7.1 6.4 11.3 2 8.2 7.9 1.7 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Iso_dh PF00180.20 CDJ49424.1 - 2.2e-14 53.4 0.0 2.5e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Spt20 PF12090.8 CDJ49425.1 - 5.3e-06 26.2 9.2 7.2e-06 25.8 9.2 1.1 1 0 0 1 1 1 1 Spt20 family Lin-8 PF03353.15 CDJ49425.1 - 0.00047 19.8 6.9 0.00063 19.4 6.9 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ49425.1 - 0.003 17.6 18.1 0.0035 17.4 18.1 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ49425.1 - 0.0036 17.3 11.8 0.0043 17.0 11.8 1.1 1 0 0 1 1 1 1 SPX domain AF-4 PF05110.13 CDJ49425.1 - 0.0056 14.9 19.3 0.007 14.5 19.3 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein RskA PF10099.9 CDJ49425.1 - 0.018 15.3 13.9 0.026 14.8 13.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA V_ATPase_I PF01496.19 CDJ49425.1 - 0.039 11.9 2.4 0.047 11.6 2.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NAD_binding_1 PF00175.21 CDJ49425.1 - 0.12 13.0 0.4 0.21 12.2 0.4 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Peroxin-3 PF04882.12 CDJ49425.1 - 0.15 11.0 10.7 0.19 10.7 10.7 1.1 1 0 0 1 1 1 0 Peroxin-3 Neur_chan_memb PF02932.16 CDJ49425.1 - 0.63 10.1 4.5 0.85 9.6 4.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ49425.1 - 0.79 9.5 8.1 0.19 11.5 1.9 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CSG2 PF16965.5 CDJ49425.1 - 1.1 8.1 3.3 1.3 7.8 3.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF1754 PF08555.10 CDJ49425.1 - 1.3 9.9 9.1 1.4 9.8 5.3 2.0 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Miga PF10265.9 CDJ49425.1 - 1.3 7.9 6.6 1.5 7.7 6.6 1.2 1 0 0 1 1 1 0 Mitoguardin Orf78 PF06024.12 CDJ49425.1 - 4.4 7.7 5.0 46 4.4 0.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) CCDC24 PF15669.5 CDJ49425.1 - 8.6 6.2 12.9 13 5.6 12.3 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Hydrolase_6 PF13344.6 CDJ49426.1 - 5.3e-12 45.7 0.0 5.3e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Presenilin PF01080.17 CDJ49426.1 - 3.3 6.4 100.3 0.076 11.8 12.1 3.1 3 0 0 3 3 3 0 Presenilin Dus PF01207.17 CDJ49428.1 - 3.8e-54 183.9 0.3 2.1e-53 181.4 0.3 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) BKACE PF05853.12 CDJ49428.1 - 0.04 13.2 0.2 0.078 12.3 0.2 1.4 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme He_PIG PF05345.12 CDJ49429.1 - 0.0053 16.9 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Putative Ig domain Alba PF01918.21 CDJ49431.1 - 6.2e-08 32.4 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 CDJ49431.1 - 2.7e-05 24.1 0.6 1.1 9.2 0.0 3.2 2 1 1 3 3 3 3 Rpp20 subunit of nuclear RNase MRP and P Ribosomal_S7e PF01251.18 CDJ49432.1 - 2.8e-63 213.0 2.0 3.1e-63 212.9 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e FtsQ PF03799.15 CDJ49432.1 - 0.046 14.5 0.5 0.36 11.7 0.2 2.1 1 1 1 2 2 2 0 Cell division protein FtsQ DnaJ PF00226.31 CDJ49433.1 - 0.0088 16.2 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain SF3b10 PF07189.11 CDJ49434.1 - 8.9e-31 105.8 0.0 1.4e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Roughex PF06020.11 CDJ49434.1 - 0.83 8.7 4.8 0.96 8.5 4.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SUIM_assoc PF16619.5 CDJ49435.1 - 0.01 15.9 5.2 0.01 15.9 5.2 13.1 8 5 1 9 9 9 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ49435.1 - 3 8.1 102.8 0.025 14.9 2.6 7.1 3 2 1 5 5 5 0 Anti-sigma-K factor rskA Rib_5-P_isom_A PF06026.14 CDJ49437.1 - 6.7e-48 162.6 0.1 6.2e-30 104.0 0.1 2.1 2 0 0 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Dynein_attach_N PF15867.5 CDJ49438.1 - 1.4e-14 53.8 0.5 2.7e-14 52.9 0.5 1.4 1 0 0 1 1 1 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 CDJ49438.1 - 0.00027 21.4 0.1 0.0019 18.7 0.0 2.2 1 1 1 2 2 2 1 Potential Monad-binding region of RPAP3 Macoilin PF09726.9 CDJ49438.1 - 0.002 16.8 1.8 0.002 16.8 1.8 2.3 2 0 0 2 2 2 1 Macoilin family DUF4667 PF15700.5 CDJ49438.1 - 0.031 14.4 6.7 0.062 13.4 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Apt1 PF10351.9 CDJ49438.1 - 0.17 10.7 2.4 0.22 10.4 2.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AF-4 PF05110.13 CDJ49438.1 - 0.33 9.0 21.7 0.04 12.0 15.3 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Neur_chan_memb PF02932.16 CDJ49438.1 - 1.6 8.7 3.6 3.1 7.8 0.6 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_pp85 PF04637.12 CDJ49438.1 - 8.6 4.6 8.0 16 3.7 8.0 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Secretin_N_2 PF07655.13 CDJ49439.1 - 0.11 13.0 17.6 0.12 12.9 9.2 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain SRP-alpha_N PF04086.13 CDJ49439.1 - 1.1 9.1 23.0 1.3 8.9 23.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF966 PF06136.13 CDJ49439.1 - 2 8.0 24.5 2.4 7.8 24.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Asp-B-Hydro_N PF05279.11 CDJ49439.1 - 6.6 6.7 11.7 8.9 6.3 11.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Macoilin PF09726.9 CDJ49439.1 - 7.5 5.0 23.0 10 4.5 23.0 1.3 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CDJ49439.1 - 8.5 6.3 21.1 9.2 6.1 21.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_2 PF12796.7 CDJ49440.1 - 0.032 14.8 0.5 0.032 14.8 0.5 2.6 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) DUF1635 PF07795.11 CDJ49440.1 - 0.32 10.8 1.9 0.72 9.7 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Herpes_pp85 PF04637.12 CDJ49440.1 - 3 6.2 3.9 4.8 5.5 3.9 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CobT PF06213.12 CDJ49441.1 - 0.028 13.8 21.5 0.031 13.7 21.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 CDJ49441.1 - 0.072 12.9 15.3 0.078 12.8 15.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.13 CDJ49441.1 - 0.084 13.5 24.4 0.098 13.3 24.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 CDJ49441.1 - 0.1 12.6 27.6 0.11 12.5 27.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Eapp_C PF10238.9 CDJ49441.1 - 0.11 12.6 15.0 0.12 12.4 15.0 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein NPR3 PF03666.13 CDJ49441.1 - 0.13 11.0 14.6 0.14 10.9 14.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 CDJ49441.1 - 0.14 12.3 13.6 0.15 12.2 13.6 1.1 1 0 0 1 1 1 0 DDHD domain NARP1 PF12569.8 CDJ49441.1 - 0.16 10.9 17.5 0.17 10.7 17.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SpoIIP PF07454.11 CDJ49441.1 - 0.22 11.0 18.1 0.25 10.8 18.1 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FemAB PF02388.16 CDJ49441.1 - 0.25 10.2 16.1 0.3 9.9 16.1 1.0 1 0 0 1 1 1 0 FemAB family Tim54 PF11711.8 CDJ49441.1 - 0.31 9.8 14.1 0.33 9.7 14.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 CDJ49441.1 - 0.34 9.6 20.1 0.38 9.5 20.1 1.0 1 0 0 1 1 1 0 Presenilin VIR_N PF15912.5 CDJ49441.1 - 0.35 10.4 8.2 0.41 10.2 8.2 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal Med19 PF10278.9 CDJ49441.1 - 0.36 10.7 11.6 0.39 10.6 11.6 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 FAM60A PF15396.6 CDJ49441.1 - 0.4 10.7 14.5 0.46 10.5 14.5 1.0 1 0 0 1 1 1 0 Protein Family FAM60A EIIBC-GUT_N PF03612.14 CDJ49441.1 - 0.4 10.4 13.5 0.53 10.0 13.5 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4746 PF15928.5 CDJ49441.1 - 0.44 9.9 12.4 0.5 9.7 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF5308 PF17233.2 CDJ49441.1 - 0.5 10.6 11.5 0.58 10.4 11.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) CPSF100_C PF13299.6 CDJ49441.1 - 0.53 10.5 13.5 0.6 10.3 13.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TERB2 PF15101.6 CDJ49441.1 - 0.53 10.3 23.5 0.6 10.1 23.5 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 AIF_C PF14721.6 CDJ49441.1 - 0.56 10.6 13.3 0.66 10.3 13.3 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term eIF-3_zeta PF05091.12 CDJ49441.1 - 0.63 8.9 25.2 0.7 8.8 25.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 CDJ49441.1 - 0.67 9.3 20.9 0.73 9.1 20.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM176 PF14851.6 CDJ49441.1 - 0.77 9.4 10.2 0.89 9.2 10.2 1.1 1 0 0 1 1 1 0 FAM176 family Baculo_PP31 PF05311.11 CDJ49441.1 - 0.8 9.1 18.6 0.95 8.9 18.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF913 PF06025.12 CDJ49441.1 - 0.83 8.6 10.4 0.89 8.5 10.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) API5 PF05918.11 CDJ49441.1 - 0.91 8.3 17.0 0.96 8.2 17.0 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Gti1_Pac2 PF09729.9 CDJ49441.1 - 0.93 9.6 14.8 1.1 9.3 14.8 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family PDCD7 PF16021.5 CDJ49441.1 - 0.93 8.6 23.5 1 8.4 23.5 1.0 1 0 0 1 1 1 0 Programmed cell death protein 7 Rxt3 PF08642.10 CDJ49441.1 - 0.99 10.2 12.6 6.2 7.6 12.6 1.9 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 CCDC53 PF10152.9 CDJ49441.1 - 1.1 9.7 18.2 1.2 9.5 18.2 1.0 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Rtf2 PF04641.12 CDJ49441.1 - 1.1 8.5 16.5 1.3 8.3 16.5 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger V_ATPase_I PF01496.19 CDJ49441.1 - 1.1 7.0 20.1 1.3 6.8 20.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATAD4 PF15321.6 CDJ49441.1 - 1.2 10.6 16.4 1.6 10.1 16.4 1.1 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Ctr PF04145.15 CDJ49441.1 - 1.2 9.7 11.2 1.4 9.5 11.2 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Membralin PF09746.9 CDJ49441.1 - 1.3 8.0 9.7 1.4 7.9 9.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein Pal1 PF08316.11 CDJ49441.1 - 1.3 9.8 7.7 1.5 9.6 7.7 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Connexin PF00029.19 CDJ49441.1 - 1.4 8.7 15.5 1.6 8.5 15.5 1.1 1 0 0 1 1 1 0 Connexin PAT1 PF09770.9 CDJ49441.1 - 1.4 7.1 26.8 1.5 7.0 26.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PTPRCAP PF15713.5 CDJ49441.1 - 1.5 9.1 16.9 1.6 9.0 16.9 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF3408 PF11888.8 CDJ49441.1 - 1.6 8.9 18.9 2.1 8.5 18.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Afi1 PF07792.12 CDJ49441.1 - 1.8 9.1 15.4 2.1 8.9 15.4 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Paf1 PF03985.13 CDJ49441.1 - 1.8 7.5 21.2 2 7.3 21.2 1.0 1 0 0 1 1 1 0 Paf1 DUF2828 PF11443.8 CDJ49441.1 - 1.8 6.6 18.4 1.9 6.5 18.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.16 CDJ49441.1 - 2 8.4 14.8 2.3 8.2 14.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asparaginase_2 PF01112.18 CDJ49441.1 - 2.1 7.3 7.9 2.3 7.2 7.9 1.2 1 0 0 1 1 1 0 Asparaginase Insulin PF00049.18 CDJ49441.1 - 2.1 9.4 14.4 3.1 8.8 14.4 1.3 1 0 0 1 1 1 0 Insulin/IGF/Relaxin family SLC12 PF03522.15 CDJ49441.1 - 2.2 7.2 17.4 2.4 7.1 17.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF1764 PF08576.10 CDJ49441.1 - 2.2 9.2 17.9 3.1 8.8 17.9 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Hid1 PF12722.7 CDJ49441.1 - 2.4 6.2 16.1 2.5 6.1 16.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BORG_CEP PF14957.6 CDJ49441.1 - 2.4 9.3 11.4 2.8 9.1 11.4 1.1 1 0 0 1 1 1 0 Cdc42 effector TFIIA PF03153.13 CDJ49441.1 - 2.9 7.8 40.7 3.3 7.6 40.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.11 CDJ49441.1 - 3.4 6.0 15.6 3.9 5.9 15.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 ALMT PF11744.8 CDJ49441.1 - 3.6 6.3 13.7 3.9 6.2 13.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Band_3_cyto PF07565.13 CDJ49441.1 - 3.8 7.2 17.4 4.4 7.0 17.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Cellulose_synt PF03552.14 CDJ49441.1 - 4 5.8 7.6 4.3 5.7 7.6 1.0 1 0 0 1 1 1 0 Cellulose synthase SPT16 PF08644.11 CDJ49441.1 - 4.1 7.6 14.6 5.5 7.1 14.6 1.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Folliculin PF11704.8 CDJ49441.1 - 4.1 7.2 14.6 4.6 7.1 14.6 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport XRN_M PF17846.1 CDJ49441.1 - 4.3 6.2 12.1 4.9 6.0 12.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Ureide_permease PF07168.11 CDJ49441.1 - 4.3 6.0 9.6 4.7 5.9 9.6 1.0 1 0 0 1 1 1 0 Ureide permease EPL1 PF10513.9 CDJ49441.1 - 4.5 7.6 18.9 6.2 7.2 18.9 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Peroxin-13_N PF04088.13 CDJ49441.1 - 4.9 7.4 11.7 6.3 7.1 11.7 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region YABBY PF04690.13 CDJ49441.1 - 5.1 7.6 13.6 5.5 7.5 13.6 1.1 1 0 0 1 1 1 0 YABBY protein MMU163 PF17119.5 CDJ49441.1 - 5.7 6.0 10.4 6.8 5.8 10.4 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Plasmodium_Vir PF05795.11 CDJ49441.1 - 6.2 6.1 11.0 6.9 6.0 11.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CLN3 PF02487.17 CDJ49441.1 - 6.2 5.7 15.0 7.2 5.5 15.0 1.0 1 0 0 1 1 1 0 CLN3 protein Spore_coat_CotO PF14153.6 CDJ49441.1 - 6.4 6.7 25.3 7.5 6.4 25.3 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Sec62 PF03839.16 CDJ49441.1 - 6.5 6.2 18.1 8.2 5.9 18.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 MecA PF05389.12 CDJ49441.1 - 8 6.0 15.7 9.7 5.7 15.7 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) OATP PF03137.20 CDJ49441.1 - 8.8 4.5 11.7 10 4.3 11.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4647 PF15504.6 CDJ49441.1 - 9.3 5.2 23.6 12 4.9 23.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) CSG2 PF16965.5 CDJ49441.1 - 9.7 5.0 12.0 11 4.8 12.0 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator VWD PF00094.25 CDJ49442.1 - 3.3 8.0 9.1 4.2 7.6 8.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type D domain RIFIN PF02009.16 CDJ49444.1 - 0.059 13.3 33.7 0.071 13.0 33.7 1.0 1 0 0 1 1 1 0 Rifin DUF726 PF05277.12 CDJ49444.1 - 0.1 11.5 0.2 0.12 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) CDC27 PF09507.10 CDJ49444.1 - 3.5 6.9 47.1 3.9 6.8 47.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CRAL_TRIO PF00650.20 CDJ49445.1 - 0.003 17.3 0.0 0.043 13.5 0.0 2.1 1 1 1 2 2 2 2 CRAL/TRIO domain Pcc1 PF09341.10 CDJ49445.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 Transcription factor Pcc1 RIBIOP_C PF04950.12 CDJ49447.1 - 8.9e-74 248.5 0.0 2.9e-73 246.9 0.0 1.8 1 1 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal CCDC66 PF15236.6 CDJ49448.1 - 1.6 8.5 29.7 0.68 9.8 21.5 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 CLAG PF03805.13 CDJ49450.1 - 0.0051 14.5 0.0 1.9 6.0 0.0 2.7 2 1 0 2 2 2 2 Cytoadherence-linked asexual protein GST_C_6 PF17171.4 CDJ49451.1 - 1.6e-11 43.8 0.0 2.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDJ49451.1 - 0.0057 16.6 2.7 0.013 15.5 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain DUF4131 PF13567.6 CDJ49452.1 - 0.0043 16.7 0.9 0.011 15.4 0.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4131) SR-25 PF10500.9 CDJ49453.1 - 0.32 10.6 26.0 0.34 10.5 26.0 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 CDJ49453.1 - 0.84 9.4 24.7 1.1 9.1 24.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) SpoIIIAH PF12685.7 CDJ49453.1 - 2 8.2 32.1 2.3 8.0 32.1 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein Pox_Ag35 PF03286.14 CDJ49453.1 - 2.4 7.9 22.9 2.7 7.8 22.9 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ASC PF00858.24 CDJ49453.1 - 4.2 6.2 18.4 4.6 6.1 18.4 1.0 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel IHABP4_N PF16174.5 CDJ49453.1 - 4.6 7.8 28.7 5 7.7 28.7 1.0 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4050 PF13259.6 CDJ49453.1 - 4.9 7.4 23.7 5.4 7.3 23.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Dsh_C PF12316.8 CDJ49453.1 - 5.5 7.3 19.0 5.8 7.3 19.0 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Bul1_C PF04426.12 CDJ49453.1 - 9.1 5.6 23.8 9.8 5.5 23.8 1.0 1 0 0 1 1 1 0 Bul1 C terminus Kinase-like PF14531.6 CDJ49454.1 - 3.7e-10 39.6 0.0 1.9e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 CDJ49454.1 - 1.2e-06 28.1 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ49454.1 - 3.7e-05 23.2 0.0 6.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CDC45 PF02724.14 CDJ49455.1 - 0.012 13.9 21.8 0.015 13.6 21.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 CDJ49455.1 - 0.054 11.6 21.1 0.072 11.2 21.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FAM60A PF15396.6 CDJ49455.1 - 0.3 11.1 20.1 0.41 10.6 20.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Sin_N PF04801.13 CDJ49455.1 - 0.34 10.1 46.7 0.39 9.9 46.7 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region PNISR PF15996.5 CDJ49455.1 - 0.43 10.8 34.1 0.58 10.4 34.1 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Peptidase_S64 PF08192.11 CDJ49455.1 - 0.82 8.1 20.7 1 7.8 20.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 SLC12 PF03522.15 CDJ49455.1 - 1.4 7.9 29.2 1.7 7.6 29.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SRP-alpha_N PF04086.13 CDJ49455.1 - 1.5 8.7 26.3 1.8 8.4 26.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Caldesmon PF02029.15 CDJ49455.1 - 1.9 7.1 30.0 2.5 6.8 30.0 1.1 1 0 0 1 1 1 0 Caldesmon Hid1 PF12722.7 CDJ49455.1 - 2.7 6.0 27.5 3.8 5.5 27.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2151 PF10221.9 CDJ49455.1 - 3.6 6.1 16.5 4.2 5.8 16.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Membralin PF09746.9 CDJ49455.1 - 5.4 6.0 19.9 6.5 5.7 19.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF4045 PF13254.6 CDJ49455.1 - 5.5 6.5 26.7 7.1 6.2 26.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Integrase_H2C2 PF17921.1 CDJ49456.1 - 3.1e-14 52.8 1.5 7.1e-14 51.7 1.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CDJ49456.1 - 9.2e-14 51.6 0.2 1.5e-13 51.0 0.2 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ49456.1 - 8e-05 22.6 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ49456.1 - 0.0031 17.3 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like zf-H2C2 PF09337.10 CDJ49456.1 - 0.0055 16.9 0.2 0.0055 16.9 0.2 1.8 2 0 0 2 2 2 1 H2C2 zinc finger IPPT PF01715.17 CDJ49457.1 - 2e-42 145.5 0.0 1.3e-26 93.8 0.0 2.4 1 1 1 2 2 2 2 IPP transferase HTH_17 PF12728.7 CDJ49457.1 - 0.0041 17.3 0.2 0.062 13.5 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain AAA_33 PF13671.6 CDJ49457.1 - 0.02 15.1 0.1 0.12 12.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ49457.1 - 0.038 14.4 0.1 0.089 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 CDJ49457.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 CDJ49457.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain TPK_catalytic PF04263.16 CDJ49458.1 - 1.9e-31 108.6 0.0 3.8e-31 107.6 0.0 1.5 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CDJ49458.1 - 6.2e-12 45.1 0.1 1.3e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain SAPS PF04499.15 CDJ49459.1 - 0.076 11.8 9.7 0.092 11.5 9.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM199X PF15814.5 CDJ49459.1 - 0.13 11.3 6.7 0.21 10.6 6.7 1.3 1 0 0 1 1 1 0 Protein family FAM199X Presenilin PF01080.17 CDJ49459.1 - 0.58 8.9 25.4 0.27 10.0 18.0 2.0 2 0 0 2 2 2 0 Presenilin CDC45 PF02724.14 CDJ49459.1 - 0.94 7.7 11.8 1 7.6 10.4 1.8 2 0 0 2 2 2 0 CDC45-like protein PNISR PF15996.5 CDJ49459.1 - 1.7 8.8 28.8 0.39 11.0 19.9 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR PPP4R2 PF09184.11 CDJ49459.1 - 2.1 7.9 20.6 3.2 7.3 20.6 1.4 1 1 0 1 1 1 0 PPP4R2 PBP_sp32 PF07222.12 CDJ49459.1 - 3.5 7.0 33.2 0.01 15.3 18.9 2.2 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Spore_coat_CotO PF14153.6 CDJ49459.1 - 3.6 7.5 27.2 0.25 11.2 16.1 2.2 2 0 0 2 2 2 0 Spore coat protein CotO CDC27 PF09507.10 CDJ49459.1 - 4 6.7 24.6 6.9 5.9 24.6 1.5 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2722 PF10846.8 CDJ49459.1 - 4.4 6.1 48.7 0.022 13.7 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ49459.1 - 7.3 7.6 32.8 2.7 9.0 20.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ49459.1 - 8.4 6.1 16.4 0.38 10.5 7.6 2.1 2 0 0 2 2 2 0 Connexin Trypan_PARP PF05887.11 CDJ49460.1 - 0.00014 21.8 7.4 0.00019 21.4 7.4 1.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Lin-8 PF03353.15 CDJ49460.1 - 0.00099 18.8 25.7 0.0013 18.4 25.7 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist DUF2052 PF09747.9 CDJ49460.1 - 0.0074 16.4 26.5 0.0074 16.4 26.5 1.5 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Shadoo PF14999.6 CDJ49460.1 - 0.039 14.1 7.9 0.076 13.1 7.9 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Apt1 PF10351.9 CDJ49460.1 - 0.045 12.6 21.8 0.063 12.1 21.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ49460.1 - 0.084 11.4 27.6 0.13 10.8 27.6 1.2 1 0 0 1 1 1 0 Macoilin family DUF2151 PF10221.9 CDJ49460.1 - 0.19 10.3 16.1 0.21 10.1 16.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator HemX PF04375.14 CDJ49460.1 - 0.34 10.2 37.5 0.5 9.6 37.5 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Peptidase_S64 PF08192.11 CDJ49460.1 - 0.92 7.9 24.5 1.2 7.5 24.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.7 CDJ49460.1 - 2.2 6.3 25.0 2.9 5.9 25.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.6 CDJ49460.1 - 2.9 7.8 26.5 1.2 9.0 21.0 2.0 2 0 0 2 2 2 0 Protein Family FAM60A O-antigen_lig PF13425.6 CDJ49460.1 - 4.2 6.1 12.9 5.4 5.7 12.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3729 PF12526.8 CDJ49460.1 - 4.5 8.9 9.3 1.1 10.9 3.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3729) VIR_N PF15912.5 CDJ49460.1 - 7.4 6.1 21.5 13 5.3 21.5 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Peptidase_S15 PF02129.18 CDJ49460.1 - 8.5 5.9 13.6 15 5.1 13.6 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) GREB1 PF15782.5 CDJ49460.1 - 10 3.1 25.4 14 2.7 25.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 CDJ49461.1 - 3.4 7.2 7.6 4 7.0 7.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF515 PF04415.12 CDJ49461.1 - 7.3 4.9 8.6 8.8 4.6 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF2828 PF11443.8 CDJ49462.1 - 3.8 5.5 21.2 4 5.4 21.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4200 PF13863.6 CDJ49465.1 - 3.2e-24 85.6 12.5 3.2e-24 85.6 12.5 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) Orbi_VP5 PF00901.17 CDJ49465.1 - 0.0022 16.5 3.8 0.0022 16.5 3.8 2.1 2 0 0 2 2 2 1 Orbivirus outer capsid protein VP5 DivIC PF04977.15 CDJ49466.1 - 6.6e-05 22.6 0.6 0.0001 22.0 0.6 1.3 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.21 CDJ49466.1 - 8.6e-05 22.6 3.0 0.00012 22.1 3.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor TMF_DNA_bd PF12329.8 CDJ49466.1 - 0.00031 20.7 2.5 0.00044 20.2 2.5 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding TSC22 PF01166.18 CDJ49466.1 - 0.00036 20.8 0.4 0.00089 19.5 0.4 1.7 1 1 0 1 1 1 1 TSC-22/dip/bun family HALZ PF02183.18 CDJ49466.1 - 0.00053 20.2 4.3 0.003 17.7 4.3 2.0 1 1 0 1 1 1 1 Homeobox associated leucine zipper Cnn_1N PF07989.11 CDJ49466.1 - 0.00054 20.1 0.2 0.0007 19.7 0.2 1.3 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 DUF2968 PF11180.8 CDJ49466.1 - 0.0012 18.6 0.5 0.0014 18.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) bZIP_2 PF07716.15 CDJ49466.1 - 0.0015 18.6 3.2 0.0027 17.8 3.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Nnf1 PF03980.14 CDJ49466.1 - 0.0026 18.1 0.1 0.0029 18.0 0.1 1.3 1 0 0 1 1 1 1 Nnf1 ZapB PF06005.12 CDJ49466.1 - 0.0058 17.0 3.7 0.0086 16.5 3.7 1.3 1 0 0 1 1 1 1 Cell division protein ZapB Csm1_N PF18504.1 CDJ49466.1 - 0.0064 16.8 2.4 0.01 16.2 2.4 1.4 1 0 0 1 1 1 1 Csm1 N-terminal domain JIP_LZII PF16471.5 CDJ49466.1 - 0.0073 16.5 2.7 0.021 15.0 2.7 1.9 1 1 0 1 1 1 1 JNK-interacting protein leucine zipper II MIP-T3_C PF17749.1 CDJ49466.1 - 0.0087 16.0 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region DUF4140 PF13600.6 CDJ49466.1 - 0.0099 16.3 0.1 0.01 16.2 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) DUF2730 PF10805.8 CDJ49466.1 - 0.011 15.8 0.1 0.013 15.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1640 PF07798.11 CDJ49466.1 - 0.012 15.6 0.9 0.024 14.7 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) FlaC_arch PF05377.11 CDJ49466.1 - 0.013 15.9 2.6 0.06 13.7 1.6 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Macoilin PF09726.9 CDJ49466.1 - 0.014 14.0 0.0 0.014 14.0 0.0 1.0 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 CDJ49466.1 - 0.016 14.2 0.1 0.016 14.1 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 CDJ49466.1 - 0.016 15.3 1.4 0.022 14.8 1.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 CDJ49466.1 - 0.017 14.4 1.5 0.023 14.0 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GIT_CC PF16559.5 CDJ49466.1 - 0.021 14.7 3.7 0.046 13.6 3.7 1.6 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Phasin PF05597.11 CDJ49466.1 - 0.029 14.4 0.4 0.43 10.6 0.0 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MbeD_MobD PF04899.12 CDJ49466.1 - 0.029 14.5 0.7 0.06 13.5 0.7 1.6 2 0 0 2 2 1 0 MbeD/MobD like APG6_N PF17675.1 CDJ49466.1 - 0.034 14.7 2.6 0.034 14.7 2.6 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 CDJ49466.1 - 0.034 13.5 0.1 0.034 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LPP PF04728.13 CDJ49466.1 - 0.038 14.4 2.0 0.061 13.7 2.0 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Prominin PF05478.11 CDJ49466.1 - 0.077 10.9 0.2 0.48 8.3 0.3 1.7 1 1 0 1 1 1 0 Prominin TRAF_BIRC3_bd PF16673.5 CDJ49466.1 - 0.13 12.0 2.9 0.17 11.7 2.0 1.5 2 0 0 2 2 1 0 TNF receptor-associated factor BIRC3 binding domain NPV_P10 PF05531.12 CDJ49466.1 - 0.14 12.7 1.1 1.1 9.8 0.3 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Bap31_Bap29_C PF18035.1 CDJ49466.1 - 0.31 11.1 4.8 0.91 9.6 4.8 1.9 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain AP2 PF00847.20 CDJ49467.1 - 7.4e-12 45.3 0.1 2e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 AP2 domain AP2 PF00847.20 CDJ49468.1 - 6.8e-10 39.0 0.0 1.7e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 AP2 domain RNA_pol_Rpc4 PF05132.14 CDJ49469.1 - 6.2e-22 78.6 0.0 6.2e-22 78.6 0.0 3.5 3 1 0 3 3 3 1 RNA polymerase III RPC4 POB3_N PF17292.2 CDJ49471.1 - 5e-24 84.6 0.2 4.1e-23 81.6 0.1 2.5 2 1 1 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 CDJ49471.1 - 5.9e-24 84.3 1.3 2.3e-23 82.4 0.0 2.4 3 0 0 3 3 3 1 Histone chaperone Rttp106-like SSrecog PF03531.14 CDJ49471.1 - 1.2e-20 73.1 0.1 4.8e-20 71.2 0.0 2.1 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) YL1 PF05764.13 CDJ49471.1 - 2.8e-06 27.7 21.6 5.2e-06 26.8 21.6 1.4 1 0 0 1 1 1 1 YL1 nuclear protein CCDC106 PF15794.5 CDJ49471.1 - 1.1 8.9 11.9 1.8 8.2 11.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Nop14 PF04147.12 CDJ49471.1 - 3.1 5.9 22.8 4.2 5.5 22.8 1.1 1 0 0 1 1 1 0 Nop14-like family Mucin PF01456.17 CDJ49472.1 - 0.00072 19.6 42.0 0.0049 16.9 15.4 2.5 2 1 0 2 2 2 2 Mucin-like glycoprotein LRR_4 PF12799.7 CDJ49472.1 - 0.081 13.4 0.2 0.2 12.1 0.1 1.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Ecl1 PF12855.7 CDJ49472.1 - 5 8.3 26.3 4.7 8.3 5.2 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Pex14_N PF04695.13 CDJ49473.1 - 0.019 15.6 10.8 0.26 12.0 10.8 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.9 CDJ49473.1 - 0.02 15.2 10.6 0.44 10.8 10.3 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Apt1 PF10351.9 CDJ49473.1 - 0.064 12.1 1.5 0.059 12.2 1.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ASD2 PF08687.11 CDJ49473.1 - 0.86 9.1 3.7 1.3 8.5 3.7 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 BAF1_ABF1 PF04684.13 CDJ49473.1 - 2 7.4 10.8 2.5 7.0 10.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CCSAP PF15748.5 CDJ49473.1 - 3.4 7.8 14.3 5 7.2 14.3 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SMYLE_N PF18615.1 CDJ49473.1 - 8.4 5.8 8.4 11 5.5 8.4 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain RVP_2 PF08284.11 CDJ49476.1 - 0.0016 18.2 0.4 0.94 9.2 0.0 2.2 1 1 1 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ49476.1 - 0.0017 18.8 0.0 0.0054 17.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ49476.1 - 0.0045 17.6 0.0 0.015 15.9 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 CDJ49476.1 - 0.006 16.9 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ49476.1 - 0.15 11.9 0.0 3.4 7.5 0.0 2.1 1 1 1 2 2 2 0 Aspartyl protease DUF4073 PF13285.6 CDJ49477.1 - 1.4 8.6 5.0 0.14 11.8 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) Methyltransf_23 PF13489.6 CDJ49478.1 - 5.2e-09 36.1 2.2 3.2e-06 27.1 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ49478.1 - 1.3e-05 25.9 4.2 0.00012 22.8 0.0 3.5 2 1 1 3 3 3 1 Methyltransferase domain DUF4834 PF16118.5 CDJ49478.1 - 0.0015 19.5 10.0 0.081 13.9 1.9 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ49478.1 - 0.0063 15.5 31.9 0.17 10.8 8.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Methyltransf_25 PF13649.6 CDJ49478.1 - 0.011 16.4 0.0 0.011 16.4 0.0 3.6 3 2 1 4 4 2 0 Methyltransferase domain MTS PF05175.14 CDJ49478.1 - 0.013 15.0 0.1 0.013 15.0 0.1 2.1 2 0 0 2 2 1 0 Methyltransferase small domain Suf PF05843.14 CDJ49478.1 - 0.021 14.8 13.7 0.055 13.4 2.8 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1980 PF09323.10 CDJ49478.1 - 0.046 13.6 0.2 2.7 7.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Methyltransf_11 PF08241.12 CDJ49478.1 - 0.095 13.4 1.5 1.9 9.2 0.0 3.3 2 1 0 2 2 2 0 Methyltransferase domain Peptidase_S49_N PF08496.10 CDJ49478.1 - 0.1 12.6 3.4 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Presenilin PF01080.17 CDJ49478.1 - 0.14 10.9 8.1 1.2 7.8 0.2 2.2 2 0 0 2 2 2 0 Presenilin DUF702 PF05142.12 CDJ49478.1 - 0.14 12.6 13.0 1.7 9.1 2.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF702) TERB2 PF15101.6 CDJ49478.1 - 0.2 11.7 13.3 0.34 10.9 2.5 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 RAB3GAP2_N PF14655.6 CDJ49478.1 - 0.23 10.7 11.3 0.078 12.2 2.4 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.8 CDJ49478.1 - 0.24 11.0 44.3 0.072 12.7 9.0 2.1 2 0 0 2 2 2 0 Spt20 family E7 PF00527.18 CDJ49478.1 - 0.26 11.5 8.6 0.35 11.1 2.7 2.5 3 0 0 3 3 2 0 E7 protein, Early protein eIF-3_zeta PF05091.12 CDJ49478.1 - 0.37 9.7 11.8 0.25 10.3 1.4 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rxt3 PF08642.10 CDJ49478.1 - 0.87 10.4 3.2 11 6.8 0.1 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 TFIIA PF03153.13 CDJ49478.1 - 0.98 9.3 50.6 0.38 10.7 17.4 2.2 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.13 CDJ49478.1 - 2 8.2 10.3 2.5 7.8 2.6 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FHIPEP PF00771.20 CDJ49478.1 - 2.4 6.5 8.6 1.1 7.6 1.9 2.2 2 0 0 2 2 2 0 FHIPEP family Orf78 PF06024.12 CDJ49478.1 - 2.7 8.3 4.5 11 6.3 0.4 2.6 2 0 0 2 2 2 0 Orf78 (ac78) Mit_KHE1 PF10173.9 CDJ49478.1 - 3.2 7.8 5.2 4.3 7.4 0.9 2.1 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Renin_r PF07850.14 CDJ49478.1 - 3.3 8.4 3.7 10 6.8 0.2 2.3 2 0 0 2 2 2 0 Renin receptor-like protein EPL1 PF10513.9 CDJ49478.1 - 3.5 8.0 12.3 8.5 6.7 1.3 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Peptidase_S64 PF08192.11 CDJ49478.1 - 3.9 5.8 9.8 0.38 9.2 2.0 2.0 2 0 0 2 2 2 0 Peptidase family S64 WASH-7_C PF14746.6 CDJ49478.1 - 4.1 7.1 10.6 0.87 9.3 0.9 2.2 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal DUF775 PF05603.12 CDJ49478.1 - 4.8 6.7 14.2 0.89 9.0 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF775) EphA2_TM PF14575.6 CDJ49478.1 - 7 7.6 7.2 20 6.2 0.7 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3273 PF11677.8 CDJ49480.1 - 2.9e-99 331.7 4.1 3.3e-99 331.5 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DcpS_C PF11969.8 CDJ49482.1 - 0.34 11.4 2.8 0.86 10.1 2.8 1.6 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding PBP1_TM PF14812.6 CDJ49482.1 - 2.7 8.4 7.8 5.1 7.5 0.2 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NPR3 PF03666.13 CDJ49484.1 - 0.027 13.3 15.0 0.028 13.2 15.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 CDJ49484.1 - 0.059 13.2 20.0 0.062 13.1 20.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MMM1 PF10296.9 CDJ49484.1 - 0.068 12.2 11.5 0.096 11.7 11.5 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DAG_kinase_N PF14513.6 CDJ49484.1 - 0.11 12.8 16.8 0.12 12.6 16.8 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Connexin PF00029.19 CDJ49484.1 - 0.11 12.3 15.0 0.15 11.8 15.0 1.2 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 CDJ49484.1 - 0.14 11.2 16.3 0.16 11.0 16.3 1.0 1 0 0 1 1 1 0 CLN3 protein CDC45 PF02724.14 CDJ49484.1 - 0.14 10.4 17.6 0.15 10.3 17.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ49484.1 - 0.17 10.6 25.2 0.2 10.4 25.2 1.0 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 CDJ49484.1 - 0.18 11.4 15.2 0.18 11.4 15.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CCDC53 PF10152.9 CDJ49484.1 - 0.21 12.0 18.9 0.31 11.4 18.9 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex ALMT PF11744.8 CDJ49484.1 - 0.22 10.3 16.7 0.24 10.2 16.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF913 PF06025.12 CDJ49484.1 - 0.22 10.5 10.2 0.23 10.4 10.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 CDJ49484.1 - 0.24 10.6 7.0 0.29 10.3 7.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Hydin_ADK PF17213.3 CDJ49484.1 - 0.24 11.7 15.0 0.33 11.2 15.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SpoIIP PF07454.11 CDJ49484.1 - 0.26 10.7 20.8 0.32 10.4 20.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AF-4 PF05110.13 CDJ49484.1 - 0.28 9.2 24.1 0.29 9.2 24.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CKAP2_C PF15297.6 CDJ49484.1 - 0.31 10.1 14.7 0.37 9.8 14.7 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF2126 PF09899.9 CDJ49484.1 - 0.32 9.0 13.5 0.38 8.8 13.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Neur_chan_memb PF02932.16 CDJ49484.1 - 0.33 11.0 17.5 0.34 10.9 17.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CCSAP PF15748.5 CDJ49484.1 - 0.45 10.6 22.9 0.51 10.5 22.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Scs3p PF10261.9 CDJ49484.1 - 0.48 9.9 5.0 0.74 9.3 5.0 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM CSG2 PF16965.5 CDJ49484.1 - 0.53 9.2 8.9 0.65 8.9 8.9 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator PAT1 PF09770.9 CDJ49484.1 - 0.69 8.1 36.6 0.69 8.1 36.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ49484.1 - 0.7 9.1 18.6 0.82 8.8 18.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Gti1_Pac2 PF09729.9 CDJ49484.1 - 0.77 9.8 18.4 0.91 9.6 18.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Endostatin PF06482.11 CDJ49484.1 - 0.78 9.2 23.5 0.93 8.9 23.5 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin BORG_CEP PF14957.6 CDJ49484.1 - 0.83 10.8 13.9 0.94 10.6 13.9 1.1 1 0 0 1 1 1 0 Cdc42 effector DUF4050 PF13259.6 CDJ49484.1 - 0.86 9.9 17.6 1 9.6 17.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF4366 PF14283.6 CDJ49484.1 - 0.9 9.6 8.6 1.3 9.1 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2370 PF10176.9 CDJ49484.1 - 0.97 9.0 10.5 1.1 8.9 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) SLC12 PF03522.15 CDJ49484.1 - 0.99 8.4 22.5 1.1 8.2 22.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 NARP1 PF12569.8 CDJ49484.1 - 0.99 8.2 19.6 1.1 8.0 19.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PBP1_TM PF14812.6 CDJ49484.1 - 1 9.8 8.2 1.6 9.1 8.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2052 PF09747.9 CDJ49484.1 - 1 9.5 21.5 1.2 9.2 21.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Ureide_permease PF07168.11 CDJ49484.1 - 1 8.0 7.3 1.3 7.7 7.3 1.2 1 0 0 1 1 1 0 Ureide permease Tim54 PF11711.8 CDJ49484.1 - 1.1 8.0 16.9 1.3 7.7 16.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4569 PF15133.6 CDJ49484.1 - 1.1 8.9 21.3 1.3 8.7 21.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Rtf2 PF04641.12 CDJ49484.1 - 1.2 8.5 17.4 1.4 8.2 17.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger FAM60A PF15396.6 CDJ49484.1 - 1.2 9.1 18.6 1.4 8.9 18.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PNISR PF15996.5 CDJ49484.1 - 1.2 9.3 23.3 1.5 9.0 23.3 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SID-1_RNA_chan PF13965.6 CDJ49484.1 - 1.3 7.3 9.7 1.5 7.2 9.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FemAB PF02388.16 CDJ49484.1 - 1.3 7.8 20.8 1.4 7.7 20.8 1.0 1 0 0 1 1 1 0 FemAB family Paramyxo_ncap PF00973.19 CDJ49484.1 - 1.3 7.8 16.0 1.5 7.6 16.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein LAP1C PF05609.12 CDJ49484.1 - 1.4 7.9 21.2 1.5 7.8 21.2 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2828 PF11443.8 CDJ49484.1 - 1.6 6.7 21.1 1.8 6.5 21.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Sec62 PF03839.16 CDJ49484.1 - 1.7 8.1 17.7 2 7.9 17.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 TFIIA PF03153.13 CDJ49484.1 - 1.7 8.5 49.0 2.4 8.1 49.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mem_trans PF03547.18 CDJ49484.1 - 1.7 6.9 6.3 1.9 6.8 6.3 1.0 1 0 0 1 1 1 0 Membrane transport protein GBP_C PF02841.14 CDJ49484.1 - 1.9 7.8 28.8 2.3 7.5 28.8 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Membralin PF09746.9 CDJ49484.1 - 2.2 7.3 13.6 2.3 7.2 13.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein Spore_coat_CotO PF14153.6 CDJ49484.1 - 2.2 8.1 28.3 2.8 7.8 28.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO RP-C_C PF11800.8 CDJ49484.1 - 2.3 8.3 18.3 2.6 8.1 18.3 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Band_3_cyto PF07565.13 CDJ49484.1 - 2.4 7.9 20.8 3.2 7.5 20.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4746 PF15928.5 CDJ49484.1 - 2.7 7.3 14.7 3.3 7.1 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) HCO3_cotransp PF00955.21 CDJ49484.1 - 2.7 6.7 10.2 3.1 6.5 10.2 1.0 1 0 0 1 1 1 0 HCO3- transporter family Hid1 PF12722.7 CDJ49484.1 - 2.9 5.9 21.3 3.3 5.7 21.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 CDJ49484.1 - 3.2 6.3 15.6 3.4 6.2 15.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PPL5 PF18168.1 CDJ49484.1 - 3.4 6.9 15.0 4 6.6 15.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF3381 PF11861.8 CDJ49484.1 - 3.7 7.3 23.2 4.9 6.9 23.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PIP5K PF01504.18 CDJ49484.1 - 3.7 6.7 17.4 4.8 6.3 17.4 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase TYW3 PF02676.14 CDJ49484.1 - 4 6.7 11.9 4.5 6.6 11.9 1.1 1 0 0 1 1 1 0 Methyltransferase TYW3 BPL_N PF09825.9 CDJ49484.1 - 4.2 6.4 13.6 4.4 6.3 13.6 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal STAC2_u1 PF16664.5 CDJ49484.1 - 4.2 7.8 13.6 6.1 7.3 13.6 1.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Asp-B-Hydro_N PF05279.11 CDJ49484.1 - 5.1 7.1 14.9 6.8 6.7 14.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Otopetrin PF03189.13 CDJ49484.1 - 5.3 5.8 14.9 6.2 5.5 14.9 1.1 1 0 0 1 1 1 0 Otopetrin eIF-3_zeta PF05091.12 CDJ49484.1 - 5.4 5.9 28.6 6.3 5.6 28.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3984 PF13136.6 CDJ49484.1 - 5.5 6.3 23.9 7.4 5.9 23.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) FliP PF00813.20 CDJ49484.1 - 6.4 6.6 8.7 7.5 6.4 8.7 1.1 1 0 0 1 1 1 0 FliP family O-antigen_lig PF13425.6 CDJ49484.1 - 6.4 5.4 11.1 7.1 5.3 11.1 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein UPF0565 PF10561.9 CDJ49484.1 - 6.6 5.8 15.8 7.4 5.7 15.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Rrn6 PF10214.9 CDJ49484.1 - 6.8 5.1 26.7 7.5 4.9 26.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Velvet PF11754.8 CDJ49484.1 - 7.2 6.5 23.1 8.6 6.2 23.1 1.1 1 0 0 1 1 1 0 Velvet factor Kei1 PF08552.11 CDJ49484.1 - 7.2 6.4 13.6 10 6.0 13.6 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 POR_N PF01855.19 CDJ49484.1 - 7.4 6.2 8.6 8.8 6.0 8.6 1.1 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Peptidase_S64 PF08192.11 CDJ49484.1 - 7.4 4.9 19.1 8.6 4.7 19.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 NST1 PF13945.6 CDJ49484.1 - 7.5 6.6 31.9 10 6.2 31.9 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Ctr PF04145.15 CDJ49484.1 - 9.1 6.9 14.7 14 6.3 14.7 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Folliculin PF11704.8 CDJ49484.1 - 9.3 6.1 17.1 11 5.8 17.1 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport CobT PF06213.12 CDJ49484.1 - 9.5 5.5 29.5 13 5.1 29.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4638 PF15472.6 CDJ49484.1 - 9.6 5.8 18.5 11 5.6 18.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) ATP-synt_I PF03899.15 CDJ49485.1 - 0.0046 17.3 0.2 0.013 15.9 0.2 1.7 1 0 0 1 1 1 1 ATP synthase I chain UPF0239 PF06783.11 CDJ49485.1 - 0.28 11.4 6.3 8.4 6.7 2.4 3.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) THOC2_N PF16134.5 CDJ49486.1 - 0.074 11.7 10.7 0.094 11.3 10.7 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Lin-8 PF03353.15 CDJ49486.1 - 0.23 11.0 12.5 0.23 11.0 12.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AAA_23 PF13476.6 CDJ49486.1 - 0.7 10.3 14.7 0.81 10.2 14.7 1.2 1 0 0 1 1 1 0 AAA domain DUF2448 PF10476.9 CDJ49486.1 - 2.5 7.9 12.8 3.9 7.3 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2448) Presenilin PF01080.17 CDJ49486.1 - 2.7 6.7 10.4 3.2 6.4 10.4 1.3 1 0 0 1 1 1 0 Presenilin Nop53 PF07767.11 CDJ49486.1 - 3 7.1 21.4 3.8 6.8 21.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DDHD PF02862.17 CDJ49488.1 - 2.2 8.4 13.7 2.8 8.0 13.7 1.3 1 0 0 1 1 1 0 DDHD domain SelP_N PF04592.14 CDJ49488.1 - 2.2 7.6 26.6 2.7 7.3 26.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIA PF03153.13 CDJ49488.1 - 2.4 8.1 41.4 2.7 7.9 41.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1708 PF08101.11 CDJ49488.1 - 2.6 7.1 10.8 3.2 6.8 10.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) DUF2992 PF11208.8 CDJ49488.1 - 4.9 7.4 23.2 6.9 6.9 23.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF2796 PF10986.8 CDJ49488.1 - 4.9 7.1 33.4 11 5.9 33.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2796) PAT1 PF09770.9 CDJ49488.1 - 7.3 4.7 28.7 7.9 4.6 28.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ49488.1 - 9.5 4.9 23.7 11 4.7 23.7 1.0 1 0 0 1 1 1 0 Presenilin Macro PF01661.21 CDJ49489.1 - 0.00014 21.9 0.0 0.00045 20.3 0.0 1.8 2 0 0 2 2 2 1 Macro domain TPP_enzyme_C PF02775.21 CDJ49489.1 - 0.00083 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Androgen_recep PF02166.16 CDJ49489.1 - 0.15 10.9 6.9 0.22 10.3 2.5 2.2 2 0 0 2 2 2 0 Androgen receptor Ribosomal_60s PF00428.19 CDJ49489.1 - 0.6 10.7 12.4 0.046 14.3 6.8 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Lipase_3 PF01764.25 CDJ49490.1 - 0.00025 20.9 0.1 0.002 18.0 0.1 2.4 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ49490.1 - 0.00033 21.3 0.1 0.00033 21.3 0.1 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family NAM-associated PF14303.6 CDJ49490.1 - 0.0051 17.5 0.0 0.0051 17.5 0.0 6.3 4 2 0 5 5 5 1 No apical meristem-associated C-terminal domain Abhydrolase_1 PF00561.20 CDJ49490.1 - 0.025 14.2 0.0 0.025 14.2 0.0 3.4 3 0 0 3 3 3 0 alpha/beta hydrolase fold UPF0564 PF10595.9 CDJ49490.1 - 0.68 8.9 45.4 0.38 9.8 20.8 3.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0564 LMBR1 PF04791.16 CDJ49490.1 - 3.8 6.3 10.0 10 4.9 10.0 1.6 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase PF00069.25 CDJ49492.1 - 3.1e-20 72.7 0.0 4e-13 49.4 0.0 5.1 5 1 0 5 5 5 2 Protein kinase domain RskA PF10099.9 CDJ49492.1 - 1.5e-06 28.6 1.0 1.5e-06 28.6 1.0 10.9 2 2 4 8 8 8 2 Anti-sigma-K factor rskA Exonuc_VII_L PF02601.15 CDJ49492.1 - 0.0031 17.1 23.7 0.0031 17.1 23.7 5.7 4 2 0 5 5 5 1 Exonuclease VII, large subunit SET PF00856.28 CDJ49492.1 - 0.0096 16.3 0.2 0.0096 16.3 0.2 6.3 3 1 0 3 3 3 1 SET domain PP2C PF00481.21 CDJ49493.1 - 3.2e-13 49.9 0.3 3.2e-13 49.9 0.3 2.3 1 1 1 2 2 2 1 Protein phosphatase 2C AAA_24 PF13479.6 CDJ49493.1 - 1.5 8.5 8.1 5.1 6.8 1.3 2.4 2 0 0 2 2 2 0 AAA domain SARAF PF06682.12 CDJ49494.1 - 0.013 15.1 0.0 0.013 15.1 0.0 7.1 4 2 3 7 7 7 0 SOCE-associated regulatory factor of calcium homoeostasis DUF5305 PF17231.2 CDJ49494.1 - 0.19 11.1 8.7 4.9 6.5 0.0 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5305) NAM-associated PF14303.6 CDJ49494.1 - 2 9.1 0.0 2 9.1 0.0 11.4 7 4 1 9 9 9 0 No apical meristem-associated C-terminal domain RRM_1 PF00076.22 CDJ49495.1 - 2.4e-13 49.7 0.0 5.9e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF755 PF05501.11 CDJ49495.1 - 0.00024 21.4 22.9 0.00024 21.4 22.9 11.2 3 1 5 9 9 9 1 Domain of unknown function (DUF755) HNF-1_N PF04814.13 CDJ49496.1 - 0.49 11.0 11.0 0.58 10.7 11.0 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus MSP1_C PF07462.11 CDJ49496.1 - 0.93 8.1 12.7 1.1 7.9 12.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Sin_N PF04801.13 CDJ49496.1 - 3.2 6.8 10.3 4 6.5 10.3 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region FSA_C PF10479.9 CDJ49496.1 - 6.1 4.9 10.9 6.8 4.7 10.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus IHABP4_N PF16174.5 CDJ49496.1 - 6.9 7.3 11.6 9.9 6.7 11.6 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal RskA PF10099.9 CDJ49496.1 - 7 6.9 28.5 10 6.3 28.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CsiV PF10972.8 CDJ49497.1 - 0.0018 18.1 1.3 0.0018 18.1 1.3 2.5 2 1 0 2 2 2 1 Peptidoglycan-binding protein, CsiV SR-25 PF10500.9 CDJ49497.1 - 0.25 10.9 29.7 11 5.5 0.0 4.3 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein PIP5K PF01504.18 CDJ49497.1 - 2.8 7.1 9.7 3.4 6.8 4.9 2.3 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase SANT_DAMP1_like PF16282.5 CDJ49498.1 - 8.6e-10 38.7 5.5 9.8e-09 35.3 2.9 3.0 2 1 0 2 2 2 1 SANT/Myb-like domain of DAMP1 TFIIA PF03153.13 CDJ49498.1 - 1.2e-05 25.5 44.1 8e-05 22.8 44.1 1.9 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 CDJ49498.1 - 0.0091 16.5 9.4 0.0091 16.5 9.4 2.2 2 0 0 2 2 2 1 AAA domain Tim29 PF10171.9 CDJ49498.1 - 0.097 12.2 2.3 0.18 11.3 2.3 1.5 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Tic110 PF16940.5 CDJ49498.1 - 2.1 6.7 18.4 1.1 7.6 13.2 2.1 2 0 0 2 2 2 0 Chloroplast envelope transporter SR-25 PF10500.9 CDJ49499.1 - 5.6e-05 22.9 58.7 0.00014 21.6 40.6 2.0 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein MRP-S31 PF15433.6 CDJ49499.1 - 3.4 7.2 47.3 4.2 6.9 47.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Menin PF05053.13 CDJ49499.1 - 4.5 5.5 40.4 5.7 5.2 40.4 1.0 1 0 0 1 1 1 0 Menin DUF936 PF06075.12 CDJ49499.1 - 6.2 5.6 44.4 7.5 5.3 44.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) MraY_sig1 PF10555.9 CDJ49500.1 - 0.96 9.1 2.2 1.6 8.4 2.2 1.3 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 DUF2722 PF10846.8 CDJ49501.1 - 0.00045 19.3 9.1 0.00045 19.3 9.1 16.0 6 4 9 15 15 15 1 Protein of unknown function (DUF2722) SARAF PF06682.12 CDJ49503.1 - 1.3e-05 25.1 4.1 1.3e-05 25.1 4.1 4.0 4 0 0 4 4 3 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 CDJ49503.1 - 0.00046 21.1 1.4 0.00046 21.1 1.4 3.6 4 0 0 4 4 3 1 Domain of unknown function (DUF4834) Tmemb_9 PF05434.11 CDJ49503.1 - 0.00063 19.7 0.2 0.00063 19.7 0.2 2.3 2 0 0 2 2 1 1 TMEM9 DUF2722 PF10846.8 CDJ49503.1 - 0.00099 18.2 11.4 0.00099 18.2 11.4 3.2 3 0 0 3 3 2 1 Protein of unknown function (DUF2722) TMEM51 PF15345.6 CDJ49503.1 - 0.0016 18.3 2.0 0.0016 18.3 2.0 3.7 4 0 0 4 4 3 1 Transmembrane protein 51 Spt20 PF12090.8 CDJ49503.1 - 0.0047 16.6 17.1 0.0047 16.6 17.1 2.6 3 0 0 3 3 2 1 Spt20 family DDHD PF02862.17 CDJ49503.1 - 0.017 15.3 9.2 0.22 11.7 0.4 3.6 3 0 0 3 3 3 0 DDHD domain MecA PF05389.12 CDJ49503.1 - 0.018 14.7 2.7 0.29 10.7 0.1 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) O-antigen_lig PF13425.6 CDJ49503.1 - 0.056 12.2 0.0 0.056 12.2 0.0 1.9 2 0 0 2 2 2 0 O-antigen ligase like membrane protein WBP-1 PF11669.8 CDJ49503.1 - 0.21 12.2 9.2 0.12 13.1 2.8 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 CLN3 PF02487.17 CDJ49503.1 - 0.28 10.2 11.3 0.0096 15.0 1.3 2.2 2 0 0 2 2 2 0 CLN3 protein DUF3169 PF11368.8 CDJ49503.1 - 0.34 10.4 1.6 0.52 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) RR_TM4-6 PF06459.12 CDJ49503.1 - 0.43 10.4 10.6 0.34 10.7 0.3 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MTABC_N PF16185.5 CDJ49503.1 - 0.56 9.7 3.3 1.3 8.4 3.3 1.5 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region YfhO PF09586.10 CDJ49503.1 - 0.61 8.3 4.4 1.2 7.2 1.1 2.0 2 0 0 2 2 2 0 Bacterial membrane protein YfhO OATP PF03137.20 CDJ49503.1 - 0.63 8.3 7.8 0.037 12.3 0.1 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SID-1_RNA_chan PF13965.6 CDJ49503.1 - 0.65 8.3 6.2 0.078 11.4 0.9 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 NEMP PF10225.9 CDJ49503.1 - 0.72 9.5 11.8 1.4 8.5 2.0 2.4 2 0 0 2 2 2 0 NEMP family G0-G1_switch_2 PF15103.6 CDJ49503.1 - 0.77 10.2 8.2 2.9 8.4 1.6 2.9 3 0 0 3 3 2 0 G0/G1 switch protein 2 Tim54 PF11711.8 CDJ49503.1 - 1 8.1 7.4 0.31 9.8 0.2 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 eIF-3_zeta PF05091.12 CDJ49503.1 - 1.2 8.0 12.3 0.056 12.4 0.3 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peroxin-13_N PF04088.13 CDJ49503.1 - 3.2 8.0 6.7 2.5 8.3 0.5 2.7 2 0 0 2 2 2 0 Peroxin 13, N-terminal region TssO PF17561.2 CDJ49503.1 - 5.1 7.2 21.3 0.73 9.9 6.9 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssO Peptidase_S49_N PF08496.10 CDJ49503.1 - 5.7 7.0 9.8 1.1 9.3 0.2 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal U1snRNP70_N PF12220.8 CDJ49503.1 - 5.7 7.6 12.1 0.56 10.9 0.6 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PigN PF04987.14 CDJ49503.1 - 7.5 5.3 9.0 0.055 12.3 0.2 1.7 2 0 0 2 2 1 0 Phosphatidylinositolglycan class N (PIG-N) Serinc PF03348.15 CDJ49503.1 - 8.2 5.2 11.6 1.1 8.0 1.8 2.9 3 0 0 3 3 3 0 Serine incorporator (Serinc) DUF2722 PF10846.8 CDJ49504.1 - 0.0019 17.2 3.0 0.0019 17.2 3.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) PAT1 PF09770.9 CDJ49504.1 - 1.9 6.7 34.0 2.9 6.1 34.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RskA PF10099.9 CDJ49505.1 - 0.013 15.8 4.6 0.013 15.8 4.6 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ49506.1 - 0.006 16.9 20.9 0.006 16.9 20.9 3.8 1 1 2 3 3 3 2 Anti-sigma-K factor rskA AAA_23 PF13476.6 CDJ49506.1 - 1.4 9.4 20.7 9 6.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain LMBR1 PF04791.16 CDJ49506.1 - 1.5 7.6 8.1 0.5 9.2 4.0 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein Serinc PF03348.15 CDJ49507.1 - 1.7 7.5 4.7 1.9 7.4 4.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.17 CDJ49507.1 - 2.5 8.2 10.7 3.5 7.7 10.7 1.3 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 CDJ49507.1 - 2.9 7.6 12.6 3.7 7.3 12.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ49507.1 - 3 6.7 17.9 3.8 6.4 17.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ49507.1 - 4.2 6.0 15.1 4.8 5.8 15.1 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ49507.1 - 6.3 4.6 11.2 7.1 4.4 11.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 CDJ49507.1 - 9.9 6.1 11.9 12 5.9 11.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NUC194 PF08163.12 CDJ49508.1 - 0.0077 15.2 1.3 0.021 13.8 1.3 1.6 1 0 0 1 1 1 1 NUC194 domain AAA_25 PF13481.6 CDJ49508.1 - 0.016 14.8 0.9 0.064 12.8 0.9 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDJ49508.1 - 0.027 14.7 0.0 0.15 12.3 0.0 2.4 1 1 0 1 1 1 0 AAA domain CT_C_D PF02682.16 CDJ49508.1 - 0.051 13.3 5.1 0.089 12.5 1.8 2.7 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D Lin-8 PF03353.15 CDJ49508.1 - 1.5 8.3 25.4 0.37 10.3 2.4 4.0 4 0 0 4 4 4 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ49508.1 - 9.5 4.9 17.5 1.1 8.1 0.8 3.2 4 0 0 4 4 4 0 Golgi-body localisation protein domain PAT1 PF09770.9 CDJ49509.1 - 1.4 7.1 32.7 2.2 6.5 32.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 KAsynt_C_assoc PF16197.5 CDJ49509.1 - 5.4 7.5 14.5 0.89 10.0 4.0 2.7 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension SR-25 PF10500.9 CDJ49510.1 - 0.0025 17.5 16.0 0.04 13.5 6.0 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 CDJ49510.1 - 0.0066 17.0 7.4 0.0088 16.6 7.4 1.2 1 0 0 1 1 1 1 AAA domain TFIIA PF03153.13 CDJ49510.1 - 0.022 14.7 47.0 0.029 14.4 47.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ49510.1 - 0.074 12.0 11.1 0.077 12.0 11.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) YbgS PF13985.6 CDJ49510.1 - 0.098 12.9 5.3 0.16 12.2 2.1 2.2 2 0 0 2 2 2 0 YbgS-like protein OATP PF03137.20 CDJ49510.1 - 0.25 9.6 5.6 0.37 9.0 5.6 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family V_ATPase_I PF01496.19 CDJ49510.1 - 0.28 9.1 9.1 0.31 8.9 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hamartin PF04388.12 CDJ49510.1 - 0.48 9.0 18.8 0.6 8.7 18.8 1.1 1 0 0 1 1 1 0 Hamartin protein Serinc PF03348.15 CDJ49510.1 - 0.77 8.6 4.6 0.88 8.4 4.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Herpes_TAF50 PF03326.13 CDJ49510.1 - 0.86 8.2 39.5 0.97 8.0 39.5 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) SpoIIP PF07454.11 CDJ49510.1 - 1.3 8.4 11.8 2.1 7.7 11.8 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EIF4E-T PF10477.9 CDJ49510.1 - 1.7 7.4 25.0 2.1 7.1 25.0 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Connexin PF00029.19 CDJ49510.1 - 3.1 7.5 8.0 5.3 6.7 8.0 1.3 1 0 0 1 1 1 0 Connexin LMBR1 PF04791.16 CDJ49510.1 - 4.8 6.0 4.3 5.3 5.8 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM60A PF15396.6 CDJ49510.1 - 5.5 6.9 11.4 7.3 6.5 6.9 2.0 2 0 0 2 2 2 0 Protein Family FAM60A GCD14 PF08704.10 CDJ49510.1 - 9.5 5.8 11.4 1.1 8.9 0.5 2.2 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit PNISR PF15996.5 CDJ49513.1 - 0.0068 16.7 6.1 0.0068 16.7 6.1 13.9 4 2 6 10 10 10 2 Arginine/serine-rich protein PNISR DUF4614 PF15391.6 CDJ49514.1 - 0.0048 16.9 2.8 0.013 15.5 2.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) Miga PF10265.9 CDJ49515.1 - 1.5 7.7 19.6 3.1 6.7 19.6 1.4 1 0 0 1 1 1 0 Mitoguardin FHIPEP PF00771.20 CDJ49515.1 - 7.3 4.9 10.2 11 4.4 10.2 1.3 1 0 0 1 1 1 0 FHIPEP family AF-4 PF05110.13 CDJ49516.1 - 0.17 9.9 51.7 0.19 9.8 51.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CCSAP PF15748.5 CDJ49516.1 - 0.41 10.8 48.5 0.47 10.6 48.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SR-25 PF10500.9 CDJ49516.1 - 1 8.9 51.1 1e+02 2.4 51.1 2.1 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4775 PF16001.5 CDJ49516.1 - 1.4 8.3 23.3 1.6 8.1 23.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) PAT1 PF09770.9 CDJ49516.1 - 1.4 7.0 52.5 1.4 7.1 52.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ49516.1 - 3.1 7.6 39.5 4.1 7.1 39.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NAM-associated PF14303.6 CDJ49516.1 - 4.5 8.0 41.7 5.4 7.7 41.7 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Nop53 PF07767.11 CDJ49516.1 - 6.8 6.0 50.2 7.7 5.8 50.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) XRN_M PF17846.1 CDJ49516.1 - 9.3 5.1 24.2 9.3 5.1 24.2 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF2052 PF09747.9 CDJ49517.1 - 0.85 9.7 13.1 0.18 11.9 8.1 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) IGPS PF00218.21 CDJ49517.1 - 0.85 8.7 5.4 0.14 11.3 0.8 1.8 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF4551 PF15087.6 CDJ49517.1 - 7.8 5.2 17.3 9.7 4.9 17.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SR-25 PF10500.9 CDJ49518.1 - 0.0026 17.4 7.3 0.0028 17.3 7.3 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ49518.1 - 0.025 15.2 6.3 0.029 15.0 6.3 1.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein Chorion_2 PF03964.15 CDJ49518.1 - 0.048 14.5 9.6 0.053 14.4 9.6 1.1 1 0 0 1 1 1 0 Chorion family 2 DUF5349 PF17298.2 CDJ49518.1 - 0.053 13.3 7.9 0.054 13.3 7.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5349) SprA-related PF12118.8 CDJ49518.1 - 0.13 11.4 12.8 0.14 11.3 12.8 1.1 1 0 0 1 1 1 0 SprA-related family Androgen_recep PF02166.16 CDJ49518.1 - 0.16 10.8 13.8 0.17 10.7 13.8 1.1 1 0 0 1 1 1 0 Androgen receptor DUF533 PF04391.12 CDJ49518.1 - 0.23 11.0 7.4 0.24 10.9 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF533) TFIIA PF03153.13 CDJ49518.1 - 0.23 11.4 13.0 0.24 11.4 13.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ49518.1 - 0.25 12.0 8.2 0.28 11.8 8.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC106 PF15794.5 CDJ49518.1 - 0.55 9.9 6.9 0.6 9.8 6.9 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDK2AP PF09806.9 CDJ49518.1 - 0.76 9.8 12.2 0.94 9.5 12.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2722 PF10846.8 CDJ49518.1 - 1.4 7.8 14.1 1.4 7.7 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF5521 PF17659.1 CDJ49518.1 - 1.6 6.5 4.5 1.6 6.5 4.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Suf PF05843.14 CDJ49518.1 - 1.6 8.7 7.6 1.6 8.6 7.6 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ49518.1 - 1.9 8.0 18.8 2.1 7.9 18.8 1.0 1 0 0 1 1 1 0 Spt20 family Coilin_N PF15862.5 CDJ49518.1 - 3.1 7.6 10.9 3.8 7.3 10.9 1.1 1 0 0 1 1 1 0 Coilin N-terminus Sox_N PF12444.8 CDJ49518.1 - 3.7 8.7 7.9 4.8 8.4 7.9 1.2 1 0 0 1 1 1 0 Sox developmental protein N terminal Kei1 PF08552.11 CDJ49518.1 - 6.8 6.5 5.6 7.3 6.4 5.6 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Presenilin PF01080.17 CDJ49519.1 - 1 8.1 46.2 1.2 7.9 46.2 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ49519.1 - 1.2 8.9 39.1 1.4 8.7 39.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ49519.1 - 2.1 7.1 29.7 2.4 6.9 29.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4045 PF13254.6 CDJ49519.1 - 5.1 6.6 33.6 6.2 6.4 33.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3807 PF12720.7 CDJ49519.1 - 5.3 7.3 46.5 9 6.5 46.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2052 PF09747.9 CDJ49519.1 - 5.8 7.0 39.6 7.4 6.6 39.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4746 PF15928.5 CDJ49519.1 - 6.1 6.2 30.8 8.8 5.7 30.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FAM60A PF15396.6 CDJ49519.1 - 6.6 6.7 32.0 8.1 6.4 32.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF572 PF04502.13 CDJ49519.1 - 6.7 6.2 32.7 8.7 5.9 32.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC45 PF02724.14 CDJ49519.1 - 7.1 4.8 37.3 7.9 4.6 37.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 CDJ49519.1 - 7.7 5.8 46.5 10 5.4 46.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) MCM_bind PF09739.9 CDJ49519.1 - 8.7 4.6 33.1 10 4.5 33.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NPR3 PF03666.13 CDJ49520.1 - 0.13 11.1 22.0 0.16 10.7 22.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 CDJ49520.1 - 0.14 12.1 18.4 0.2 11.7 18.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2151 PF10221.9 CDJ49520.1 - 0.22 10.1 12.7 0.25 9.9 12.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.14 CDJ49520.1 - 0.24 9.7 20.7 0.27 9.5 20.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.11 CDJ49520.1 - 0.26 9.7 17.8 0.32 9.4 17.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 SLC12 PF03522.15 CDJ49520.1 - 1 8.3 25.8 1.3 8.0 25.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Sin_N PF04801.13 CDJ49520.1 - 2.3 7.4 42.9 2.7 7.1 42.9 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF2126 PF09899.9 CDJ49520.1 - 2.5 6.1 16.5 2.5 6.1 16.5 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PLA2_B PF01735.18 CDJ49520.1 - 3.4 5.9 6.5 4.9 5.4 6.5 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Zip PF02535.22 CDJ49520.1 - 6.3 5.9 16.6 7.8 5.6 16.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter ORC6 PF05460.13 CDJ49520.1 - 6.7 5.9 23.1 8.6 5.5 23.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MDM10 PF12519.8 CDJ49520.1 - 7 5.4 21.3 8.5 5.1 21.3 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 TFIIA PF03153.13 CDJ49521.1 - 0.00019 21.6 24.4 0.0002 21.5 24.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GBP_C PF02841.14 CDJ49521.1 - 0.00023 20.7 11.2 0.00023 20.7 11.2 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain DUF2722 PF10846.8 CDJ49521.1 - 0.00034 19.7 15.0 0.00046 19.3 15.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DDHD PF02862.17 CDJ49521.1 - 0.0017 18.5 5.9 0.002 18.4 5.9 1.2 1 0 0 1 1 1 1 DDHD domain SprA-related PF12118.8 CDJ49521.1 - 0.003 16.8 22.9 0.0035 16.6 22.9 1.1 1 0 0 1 1 1 1 SprA-related family SpoIIP PF07454.11 CDJ49521.1 - 0.0042 16.6 8.9 0.0046 16.4 8.9 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 CDJ49521.1 - 0.0052 15.2 8.0 0.0059 15.0 8.0 1.1 1 0 0 1 1 1 1 CDC45-like protein Suf PF05843.14 CDJ49521.1 - 0.0054 16.8 8.6 0.0061 16.6 8.6 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Roughex PF06020.11 CDJ49521.1 - 0.0083 15.3 13.1 0.01 14.9 13.1 1.1 1 0 0 1 1 1 1 Drosophila roughex protein Presenilin PF01080.17 CDJ49521.1 - 0.0088 14.8 14.0 0.01 14.7 14.0 1.1 1 0 0 1 1 1 1 Presenilin Velvet PF11754.8 CDJ49521.1 - 0.0093 15.9 6.6 0.01 15.8 6.6 1.2 1 0 0 1 1 1 1 Velvet factor Pex14_N PF04695.13 CDJ49521.1 - 0.0095 16.6 18.0 0.015 15.9 18.0 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4045 PF13254.6 CDJ49521.1 - 0.01 15.5 8.3 0.011 15.5 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RskA PF10099.9 CDJ49521.1 - 0.011 16.1 14.5 0.018 15.3 14.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Neur_chan_memb PF02932.16 CDJ49521.1 - 0.014 15.5 4.7 0.014 15.5 4.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1387 PF07139.11 CDJ49521.1 - 0.016 15.0 9.5 0.019 14.7 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Raftlin PF15250.6 CDJ49521.1 - 0.02 13.6 8.8 0.022 13.6 8.8 1.1 1 0 0 1 1 1 0 Raftlin Lin-8 PF03353.15 CDJ49521.1 - 0.022 14.3 10.0 0.025 14.1 10.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 CDJ49521.1 - 0.033 12.5 17.7 0.036 12.4 17.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.10 CDJ49521.1 - 0.037 12.7 21.8 0.054 12.2 21.8 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PPP4R2 PF09184.11 CDJ49521.1 - 0.041 13.5 5.5 0.049 13.2 5.5 1.1 1 0 0 1 1 1 0 PPP4R2 Ribosomal_60s PF00428.19 CDJ49521.1 - 0.047 14.3 16.6 0.096 13.3 16.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein eIF-3_zeta PF05091.12 CDJ49521.1 - 0.053 12.5 14.0 0.061 12.3 14.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.6 CDJ49521.1 - 0.058 11.8 2.2 0.065 11.6 2.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AIF_C PF14721.6 CDJ49521.1 - 0.06 13.7 8.6 0.1 12.9 8.6 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Med3 PF11593.8 CDJ49521.1 - 0.068 12.3 29.5 0.13 11.5 29.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RR_TM4-6 PF06459.12 CDJ49521.1 - 0.07 13.0 16.2 0.086 12.6 16.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hamartin PF04388.12 CDJ49521.1 - 0.074 11.7 7.8 0.075 11.7 7.8 1.1 1 0 0 1 1 1 0 Hamartin protein DUF5427 PF10310.9 CDJ49521.1 - 0.075 12.0 19.2 0.095 11.6 19.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Zip PF02535.22 CDJ49521.1 - 0.076 12.2 5.5 0.095 11.9 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PPL5 PF18168.1 CDJ49521.1 - 0.088 12.1 8.2 0.12 11.7 8.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 EPL1 PF10513.9 CDJ49521.1 - 0.09 13.2 9.4 0.12 12.8 9.4 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Endostatin PF06482.11 CDJ49521.1 - 0.1 12.1 9.6 0.12 11.8 9.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF913 PF06025.12 CDJ49521.1 - 0.1 11.6 7.2 0.12 11.3 7.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4569 PF15133.6 CDJ49521.1 - 0.11 12.2 12.6 0.13 12.0 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) GvpL_GvpF PF06386.11 CDJ49521.1 - 0.11 12.4 13.2 0.15 12.0 13.2 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF FancD2 PF14631.6 CDJ49521.1 - 0.11 9.8 8.3 0.13 9.6 8.3 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease BAF1_ABF1 PF04684.13 CDJ49521.1 - 0.12 11.5 16.0 0.14 11.2 16.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FAM199X PF15814.5 CDJ49521.1 - 0.12 11.4 6.6 0.19 10.8 6.6 1.3 1 0 0 1 1 1 0 Protein family FAM199X DUF4758 PF15950.5 CDJ49521.1 - 0.13 12.6 8.9 0.61 10.4 8.9 1.9 1 1 0 1 1 1 0 Putative sperm flagellar membrane protein PA26 PF04636.13 CDJ49521.1 - 0.13 11.1 7.9 0.16 10.9 7.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Activator_LAG-3 PF11498.8 CDJ49521.1 - 0.14 11.1 30.9 0.18 10.7 30.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF1980 PF09323.10 CDJ49521.1 - 0.15 11.9 5.5 0.18 11.7 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SLC12 PF03522.15 CDJ49521.1 - 0.16 11.0 10.4 0.18 10.8 10.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF719 PF05334.13 CDJ49521.1 - 0.16 12.1 14.4 0.23 11.6 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Paf1 PF03985.13 CDJ49521.1 - 0.17 10.9 17.2 0.22 10.5 17.2 1.1 1 0 0 1 1 1 0 Paf1 CobT PF06213.12 CDJ49521.1 - 0.19 11.1 22.6 0.27 10.6 22.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Spore_coat_CotO PF14153.6 CDJ49521.1 - 0.19 11.6 18.4 0.24 11.3 18.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO ALMT PF11744.8 CDJ49521.1 - 0.19 10.5 5.5 0.18 10.6 5.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3533 PF12051.8 CDJ49521.1 - 0.2 10.6 3.9 0.2 10.6 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Ndc1_Nup PF09531.10 CDJ49521.1 - 0.21 10.2 7.5 0.22 10.1 7.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Smg8_Smg9 PF10220.9 CDJ49521.1 - 0.21 9.8 10.8 0.24 9.7 10.8 1.0 1 0 0 1 1 1 0 Smg8_Smg9 CCSAP PF15748.5 CDJ49521.1 - 0.23 11.6 16.5 0.29 11.3 16.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF5523 PF17661.1 CDJ49521.1 - 0.23 11.1 13.2 0.3 10.8 13.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Serinc PF03348.15 CDJ49521.1 - 0.25 10.2 7.2 0.32 9.9 7.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) PknG_rubred PF16919.5 CDJ49521.1 - 0.26 11.4 10.8 0.5 10.5 10.8 1.5 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain SelP_N PF04592.14 CDJ49521.1 - 0.27 10.6 16.0 0.37 10.2 16.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NARP1 PF12569.8 CDJ49521.1 - 0.28 10.0 14.9 0.36 9.7 14.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MCM_bind PF09739.9 CDJ49521.1 - 0.3 9.5 9.4 0.33 9.3 9.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4228 PF14009.6 CDJ49521.1 - 0.3 11.4 6.7 0.42 11.0 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Plasmodium_Vir PF05795.11 CDJ49521.1 - 0.3 10.4 3.7 0.3 10.5 3.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SAPS PF04499.15 CDJ49521.1 - 0.31 9.8 9.2 0.33 9.7 9.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4175 PF13779.6 CDJ49521.1 - 0.31 8.9 25.8 0.37 8.7 25.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ctr PF04145.15 CDJ49521.1 - 0.31 11.6 2.2 0.4 11.3 2.2 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Folate_carrier PF01770.18 CDJ49521.1 - 0.32 9.7 3.9 0.39 9.4 3.9 1.2 1 0 0 1 1 1 0 Reduced folate carrier Ureide_permease PF07168.11 CDJ49521.1 - 0.4 9.4 5.0 0.52 9.0 5.0 1.1 1 0 0 1 1 1 0 Ureide permease Sec62 PF03839.16 CDJ49521.1 - 0.44 10.0 7.6 0.6 9.6 7.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1682 PF07946.14 CDJ49521.1 - 0.48 9.6 9.7 0.54 9.4 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3584 PF12128.8 CDJ49521.1 - 0.54 7.7 21.3 0.63 7.5 21.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CAF1 PF04857.20 CDJ49521.1 - 0.54 9.4 8.7 0.75 8.9 8.7 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease R_equi_Vir PF05526.11 CDJ49521.1 - 0.62 9.9 9.6 0.97 9.3 9.6 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein BORG_CEP PF14957.6 CDJ49521.1 - 0.62 11.2 6.6 0.9 10.7 6.6 1.3 1 0 0 1 1 1 0 Cdc42 effector DUF3824 PF12868.7 CDJ49521.1 - 0.85 10.3 16.5 1.8 9.2 16.5 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) XRN_M PF17846.1 CDJ49521.1 - 0.93 8.4 9.6 1.1 8.2 9.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain OATP PF03137.20 CDJ49521.1 - 0.96 7.7 3.4 1.1 7.5 3.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EOS1 PF12326.8 CDJ49521.1 - 1.2 9.1 5.1 1.6 8.7 5.1 1.3 1 0 0 1 1 1 0 N-glycosylation protein PMSI1 PF15322.6 CDJ49521.1 - 1.2 8.5 12.1 1.6 8.1 12.1 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Gti1_Pac2 PF09729.9 CDJ49521.1 - 1.5 8.9 10.5 2.1 8.4 10.5 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Paramyxo_ncap PF00973.19 CDJ49521.1 - 1.5 7.7 7.6 1.6 7.6 7.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Membralin PF09746.9 CDJ49521.1 - 1.6 7.7 5.3 2 7.3 5.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein Herpes_UL32 PF06070.11 CDJ49521.1 - 1.6 6.4 9.8 2 6.0 9.8 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 RPN2_C PF18004.1 CDJ49521.1 - 1.8 8.5 17.3 2.4 8.1 17.3 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PARM PF17061.5 CDJ49521.1 - 2 8.5 10.4 2.3 8.3 10.4 1.1 1 0 0 1 1 1 0 PARM Hydin_ADK PF17213.3 CDJ49521.1 - 2.2 8.5 14.5 3.1 8.0 14.5 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain O-antigen_lig PF13425.6 CDJ49521.1 - 2.2 7.0 4.8 2.8 6.6 4.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Baculo_PP31 PF05311.11 CDJ49521.1 - 2.5 7.5 10.7 3.4 7.1 10.7 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Peptidase_U57 PF05582.12 CDJ49521.1 - 2.5 7.3 10.0 3.3 6.9 10.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Hid1 PF12722.7 CDJ49521.1 - 2.5 6.1 12.9 2.9 5.9 12.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TRAP_alpha PF03896.16 CDJ49521.1 - 2.6 7.2 11.0 3.4 6.8 11.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit VIR_N PF15912.5 CDJ49521.1 - 2.8 7.5 9.1 3.7 7.1 9.1 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF3292 PF11696.8 CDJ49521.1 - 2.8 6.2 11.7 3.6 5.8 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) NPR3 PF03666.13 CDJ49521.1 - 2.9 6.6 12.5 3.5 6.3 12.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MMR1 PF08505.10 CDJ49521.1 - 2.9 8.1 17.0 4.1 7.6 17.0 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GREB1 PF15782.5 CDJ49521.1 - 2.9 4.9 13.8 3.2 4.8 13.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Band_3_cyto PF07565.13 CDJ49521.1 - 3.1 7.5 10.9 4 7.2 10.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF5521 PF17659.1 CDJ49521.1 - 3.2 5.5 8.6 4.2 5.1 8.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) TraV PF09676.10 CDJ49521.1 - 3.4 8.7 17.1 7 7.6 17.1 1.6 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF4407 PF14362.6 CDJ49521.1 - 4 6.7 22.5 5.4 6.3 22.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) F-protein PF00469.20 CDJ49521.1 - 4.6 6.8 13.5 6.3 6.3 13.5 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef EMC3_TMCO1 PF01956.16 CDJ49521.1 - 6.5 6.4 7.8 8.2 6.1 7.8 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MAJIN PF15077.6 CDJ49521.1 - 6.8 6.4 9.8 9 6.0 9.8 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein TFB6 PF17110.5 CDJ49521.1 - 7.1 6.4 9.9 11 5.7 9.6 1.5 2 0 0 2 2 1 0 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 CDJ49521.1 - 8.1 6.1 10.1 12 5.5 10.1 1.3 1 0 0 1 1 1 0 FAM176 family DUF4746 PF15928.5 CDJ49521.1 - 9.1 5.6 12.0 13 5.1 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1712 PF08217.11 CDJ49522.1 - 2.5e-10 39.5 0.0 4.3e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) PAT1 PF09770.9 CDJ49522.1 - 0.24 9.7 13.6 0.44 8.8 0.4 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Di19_C PF14571.6 CDJ49522.1 - 4.2 8.0 10.9 4.5 7.9 1.5 2.5 2 1 0 2 2 2 0 Stress-induced protein Di19, C-terminal Tom22 PF04281.13 CDJ49522.1 - 7.5 6.3 12.3 0.24 11.2 1.2 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Pex14_N PF04695.13 CDJ49524.1 - 0.016 15.8 35.0 0.022 15.4 35.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.19 CDJ49524.1 - 0.44 8.4 24.0 0.44 8.4 24.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BAF1_ABF1 PF04684.13 CDJ49524.1 - 0.62 9.0 32.4 0.75 8.8 32.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NPR3 PF03666.13 CDJ49524.1 - 0.77 8.5 25.2 0.82 8.4 25.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SARAF PF06682.12 CDJ49524.1 - 1.7 8.2 23.4 2 8.0 23.4 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3292 PF11696.8 CDJ49524.1 - 2 6.7 25.6 2.5 6.4 25.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) FRQ PF09421.10 CDJ49524.1 - 2.3 6.1 18.2 2.7 5.9 18.2 1.0 1 0 0 1 1 1 0 Frequency clock protein DDRGK PF09756.9 CDJ49524.1 - 2.6 7.6 36.4 3.9 7.0 36.4 1.4 1 0 0 1 1 1 0 DDRGK domain DUF3295 PF11702.8 CDJ49524.1 - 2.7 7.3 26.6 3.5 6.9 26.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Draxin PF15550.6 CDJ49524.1 - 3.1 7.6 19.3 4.1 7.2 19.3 1.2 1 0 0 1 1 1 0 Draxin NST1 PF13945.6 CDJ49524.1 - 3.9 7.6 35.0 5.3 7.1 35.0 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Miga PF10265.9 CDJ49524.1 - 4.1 6.3 20.0 4.7 6.1 20.0 1.0 1 0 0 1 1 1 0 Mitoguardin DUF3807 PF12720.7 CDJ49524.1 - 4.2 7.6 35.9 6.5 7.0 35.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Presenilin PF01080.17 CDJ49524.1 - 4.2 6.0 34.9 5.1 5.7 34.9 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 CDJ49524.1 - 4.8 5.5 25.4 5.5 5.4 25.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 ETRAMP PF09716.10 CDJ49524.1 - 5.1 7.2 5.1 10 6.3 5.1 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PA26 PF04636.13 CDJ49524.1 - 5.1 5.9 24.0 5.7 5.8 24.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) eIF-3_zeta PF05091.12 CDJ49524.1 - 5.2 5.9 32.1 6.4 5.6 32.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ49524.1 - 5.4 5.9 28.7 5.9 5.8 28.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Paf1 PF03985.13 CDJ49524.1 - 6.2 5.7 32.0 8.2 5.3 32.0 1.4 1 0 0 1 1 1 0 Paf1 DUF4638 PF15472.6 CDJ49524.1 - 6.4 6.4 22.3 7.7 6.2 22.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) CDC45 PF02724.14 CDJ49524.1 - 8 4.6 25.7 8.7 4.5 25.7 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 CDJ49524.1 - 8.7 5.0 23.4 10 4.8 23.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM60A PF15396.6 CDJ49524.1 - 9.5 6.2 21.7 12 5.9 21.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PEX11 PF05648.14 CDJ49525.1 - 0.0009 18.8 1.7 0.0009 18.8 1.7 1.7 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) TFIIA PF03153.13 CDJ49525.1 - 0.0016 18.5 8.4 0.0017 18.5 8.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Septin PF00735.18 CDJ49525.1 - 0.0034 16.7 0.9 0.0049 16.2 0.9 1.2 1 0 0 1 1 1 1 Septin DUF2722 PF10846.8 CDJ49525.1 - 0.014 14.4 10.0 0.019 14.0 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Peptidase_S64 PF08192.11 CDJ49525.1 - 0.021 13.3 5.2 0.025 13.1 5.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4457 PF14652.6 CDJ49525.1 - 0.025 13.8 0.6 0.03 13.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) FAM176 PF14851.6 CDJ49525.1 - 0.026 14.2 1.3 0.041 13.6 1.3 1.3 1 0 0 1 1 1 0 FAM176 family TrbI PF03743.14 CDJ49525.1 - 0.032 14.1 0.7 0.032 14.1 0.7 1.5 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein BBS2_C PF14782.6 CDJ49525.1 - 0.041 12.7 5.3 0.056 12.2 5.3 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal PAP_central PF04928.17 CDJ49525.1 - 0.069 12.1 0.9 0.089 11.8 0.9 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF3523 PF12037.8 CDJ49525.1 - 0.084 12.2 11.7 0.12 11.7 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Suf PF05843.14 CDJ49525.1 - 0.14 12.1 4.7 0.18 11.7 4.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ribonuc_2-5A PF06479.12 CDJ49525.1 - 0.15 12.2 6.2 0.085 13.0 3.3 2.1 2 1 0 2 2 2 0 Ribonuclease 2-5A Syntaxin-6_N PF09177.11 CDJ49525.1 - 0.18 12.4 7.4 1.8 9.2 6.4 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Presenilin PF01080.17 CDJ49525.1 - 0.27 10.0 2.5 0.3 9.8 2.5 1.1 1 0 0 1 1 1 0 Presenilin FapA PF03961.13 CDJ49525.1 - 0.28 9.8 3.3 0.34 9.5 3.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_23 PF13476.6 CDJ49525.1 - 0.28 11.7 9.9 0.031 14.8 4.7 1.8 2 0 0 2 2 2 0 AAA domain Paramyxo_NS_C PF02725.14 CDJ49525.1 - 0.65 10.1 4.7 1 9.5 4.7 1.2 1 0 0 1 1 1 0 Non-structural protein C LCD1 PF09798.9 CDJ49525.1 - 0.72 8.3 11.7 1.1 7.7 11.7 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3573 PF12097.8 CDJ49525.1 - 2.9 6.6 5.7 3.6 6.3 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) PCRF PF03462.18 CDJ49525.1 - 3.2 7.6 10.2 6.3 6.6 10.2 1.5 1 1 0 1 1 1 0 PCRF domain Androgen_recep PF02166.16 CDJ49525.1 - 4.6 6.0 21.1 0.091 11.6 11.9 2.2 2 0 0 2 2 2 0 Androgen receptor FlaG PF03646.15 CDJ49525.1 - 4.9 7.4 14.3 12 6.1 14.3 1.6 1 0 0 1 1 1 0 FlaG protein DUF2722 PF10846.8 CDJ49526.1 - 0.00071 18.6 5.8 0.00071 18.6 5.8 7.5 4 2 3 7 7 7 2 Protein of unknown function (DUF2722) DUF4207 PF13904.6 CDJ49526.1 - 0.0017 18.1 12.4 0.0017 18.1 12.4 6.3 6 1 1 7 7 7 2 Domain of unknown function (DUF4207) GT87 PF09594.10 CDJ49528.1 - 1.3 8.7 18.4 1.2 8.8 1.5 2.8 3 0 0 3 3 3 0 Glycosyltransferase family 87 Sin_N PF04801.13 CDJ49529.1 - 7.7e-06 25.4 10.3 0.0009 18.6 0.1 8.0 5 3 1 7 7 7 3 Sin-like protein conserved region RskA PF10099.9 CDJ49529.1 - 0.0019 18.5 3.9 0.0019 18.5 3.9 12.6 3 3 9 12 12 12 3 Anti-sigma-K factor rskA DUF1387 PF07139.11 CDJ49530.1 - 3.1 7.4 40.9 3.9 7.1 40.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) LAP1C PF05609.12 CDJ49531.1 - 0.29 10.2 22.5 0.36 9.9 22.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF572 PF04502.13 CDJ49531.1 - 0.87 9.1 16.7 1.2 8.6 16.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) LMBR1 PF04791.16 CDJ49531.1 - 0.89 8.4 3.1 1 8.2 3.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S64 PF08192.11 CDJ49531.1 - 1.9 6.9 15.5 2.4 6.5 15.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 CCSAP PF15748.5 CDJ49531.1 - 6.6 6.8 23.3 1.7 8.8 14.1 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Shadoo PF14999.6 CDJ49532.1 - 0.0049 17.0 1.0 0.0056 16.8 1.0 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.19 CDJ49532.1 - 0.53 10.9 12.6 0.81 10.3 12.6 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein SelP_N PF04592.14 CDJ49532.1 - 0.73 9.2 25.8 0.88 8.9 25.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BAF1_ABF1 PF04684.13 CDJ49532.1 - 0.99 8.4 18.8 1.2 8.1 18.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Peptidase_S49_N PF08496.10 CDJ49532.1 - 1.5 8.8 9.8 1.9 8.5 9.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SARAF PF06682.12 CDJ49532.1 - 4 7.0 16.1 4.5 6.8 16.1 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis RR_TM4-6 PF06459.12 CDJ49532.1 - 4.5 7.0 20.2 5 6.9 20.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAT PF03417.16 CDJ49532.1 - 7.1 6.2 15.7 7.8 6.1 15.7 1.1 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase YjbH PF06082.11 CDJ49533.1 - 0.52 9.1 5.7 0.8 8.4 5.7 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Amino_oxidase PF01593.24 CDJ49534.1 - 9.7e-14 51.5 1.2 1.7e-07 30.9 0.1 5.2 5 2 0 6 6 6 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ49534.1 - 6.3e-09 35.9 0.1 6.3e-09 35.9 0.1 4.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CDJ49534.1 - 0.0022 17.3 0.0 0.0069 15.6 0.0 1.9 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CDJ49534.1 - 0.0029 18.1 0.0 0.013 16.0 0.0 2.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase RskA PF10099.9 CDJ49534.1 - 0.004 17.5 15.4 0.004 17.5 15.4 28.8 6 6 11 18 18 18 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ49535.1 - 0.0047 17.0 10.2 0.0047 17.0 10.2 9.9 5 4 1 7 7 7 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ49535.1 - 0.0057 17.0 4.2 0.0057 17.0 4.2 16.0 4 4 4 12 12 12 3 Anti-sigma-K factor rskA Sporozoite_P67 PF05642.11 CDJ49537.1 - 0.00013 20.2 0.0 0.00018 19.7 0.0 1.3 1 1 0 1 1 1 1 Sporozoite P67 surface antigen BORG_CEP PF14957.6 CDJ49537.1 - 8 7.7 17.1 5.7 8.1 6.5 2.3 2 0 0 2 2 2 0 Cdc42 effector FH2 PF02181.23 CDJ49538.1 - 1.6e-32 113.1 2.7 2.6e-28 99.2 0.2 4.7 5 1 0 5 5 5 2 Formin Homology 2 Domain DDRGK PF09756.9 CDJ49538.1 - 1.8 8.1 0.0 1.8 8.1 0.0 5.0 4 1 0 4 4 4 0 DDRGK domain Prefoldin PF02996.17 CDJ49539.1 - 0.069 13.1 5.2 2.9 7.8 0.0 3.6 2 1 2 4 4 4 0 Prefoldin subunit DUF3972 PF13118.6 CDJ49539.1 - 1.6 9.2 9.6 20 5.6 1.8 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF3972) UPF0242 PF06785.11 CDJ49539.1 - 2.6 8.1 24.2 1.1 9.4 10.8 2.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus YtxH PF12732.7 CDJ49539.1 - 3.6 8.2 16.9 81 3.9 0.1 3.7 2 1 0 2 2 2 0 YtxH-like protein TFIIA PF03153.13 CDJ49541.1 - 0.11 12.5 26.6 0.024 14.6 9.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ49543.1 - 4.3e-06 26.5 2.6 4.3e-06 26.5 2.6 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ49543.1 - 0.0011 19.4 11.2 0.0011 19.4 11.2 2.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA RcpC PF16976.5 CDJ49543.1 - 0.008 16.2 1.3 0.008 16.2 1.3 2.1 2 0 0 2 2 2 1 Flp pilus assembly protein RcpC/CpaB DUF4820 PF16091.5 CDJ49543.1 - 0.008 15.6 4.0 0.008 15.6 4.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4820) Suf PF05843.14 CDJ49543.1 - 0.0091 16.0 5.4 0.0091 16.0 5.4 2.0 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) TRAP_alpha PF03896.16 CDJ49543.1 - 0.039 13.2 1.5 0.051 12.8 1.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SMYLE_N PF18615.1 CDJ49543.1 - 0.07 12.7 3.7 0.073 12.6 3.7 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain OATP PF03137.20 CDJ49543.1 - 0.18 10.1 0.8 0.23 9.7 0.8 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Neur_chan_memb PF02932.16 CDJ49543.1 - 0.37 10.8 2.1 0.53 10.3 2.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM176 PF14851.6 CDJ49543.1 - 0.66 9.6 5.6 1.2 8.8 5.6 1.4 1 0 0 1 1 1 0 FAM176 family TCP PF03634.13 CDJ49543.1 - 2.7 8.5 13.6 0.12 12.9 8.2 1.5 2 0 0 2 2 2 0 TCP family transcription factor Velvet PF11754.8 CDJ49543.1 - 6.9 6.5 16.4 8.1 6.3 16.4 1.3 1 1 0 1 1 1 0 Velvet factor ANAPC_CDC26 PF10471.9 CDJ49543.1 - 7.3 7.5 26.3 0.57 11.0 13.9 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 TFIIA PF03153.13 CDJ49543.1 - 7.7 6.4 26.1 0.33 10.9 15.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit eIF_4EBP PF05456.11 CDJ49543.1 - 7.8 6.5 11.1 0.62 10.0 6.1 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Tic110 PF16940.5 CDJ49543.1 - 9.6 4.6 13.5 0.16 10.5 3.9 2.0 2 0 0 2 2 2 0 Chloroplast envelope transporter Presenilin PF01080.17 CDJ49544.1 - 0.0052 15.6 15.0 0.0057 15.5 15.0 1.0 1 0 0 1 1 1 1 Presenilin MDFI PF15316.6 CDJ49544.1 - 0.012 15.7 17.0 0.015 15.4 17.0 1.1 1 0 0 1 1 1 0 MyoD family inhibitor BORG_CEP PF14957.6 CDJ49544.1 - 0.15 13.2 12.5 0.23 12.6 12.5 1.2 1 0 0 1 1 1 0 Cdc42 effector MDM10 PF12519.8 CDJ49544.1 - 0.3 9.9 14.2 0.34 9.7 14.2 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Exonuc_VII_L PF02601.15 CDJ49544.1 - 0.65 9.5 23.0 0.7 9.4 23.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CAF1 PF04857.20 CDJ49544.1 - 0.69 9.0 10.2 0.74 8.9 10.2 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Velvet PF11754.8 CDJ49544.1 - 0.85 9.5 16.4 1.4 8.8 16.4 1.3 1 0 0 1 1 1 0 Velvet factor Calpain_inhib PF00748.19 CDJ49544.1 - 0.93 10.0 9.5 1.4 9.4 9.5 1.2 1 0 0 1 1 1 0 Calpain inhibitor DDHD PF02862.17 CDJ49544.1 - 0.95 9.6 11.9 1.2 9.2 11.9 1.3 1 0 0 1 1 1 0 DDHD domain GREB1 PF15782.5 CDJ49544.1 - 0.97 6.5 17.7 1.1 6.3 17.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 CDJ49544.1 - 1.1 8.3 21.1 1.3 8.0 21.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Lin-8 PF03353.15 CDJ49544.1 - 1.3 8.6 21.3 1.6 8.2 21.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ofd1_CTDD PF10637.9 CDJ49544.1 - 2 7.7 12.0 2.6 7.3 12.0 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Neur_chan_memb PF02932.16 CDJ49544.1 - 2 8.4 18.3 2.4 8.2 18.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 CDJ49544.1 - 2.1 7.3 21.5 2.5 7.1 21.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Membralin PF09746.9 CDJ49544.1 - 2.3 7.2 12.2 2.4 7.1 12.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein DDRGK PF09756.9 CDJ49544.1 - 2.4 7.7 26.0 3.1 7.3 26.0 1.2 1 0 0 1 1 1 0 DDRGK domain Ndc1_Nup PF09531.10 CDJ49544.1 - 2.6 6.6 13.5 2.9 6.4 13.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 CDJ49544.1 - 2.7 7.9 45.6 3.7 7.5 45.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FUSC PF04632.12 CDJ49544.1 - 2.8 6.3 16.0 3.4 6.1 16.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CPSF100_C PF13299.6 CDJ49544.1 - 3.1 7.9 12.5 4.4 7.4 12.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Suf PF05843.14 CDJ49544.1 - 3.2 7.7 22.3 5 7.0 22.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ALMT PF11744.8 CDJ49544.1 - 3.4 6.4 15.1 3.8 6.2 15.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Gti1_Pac2 PF09729.9 CDJ49544.1 - 4.7 7.3 15.0 5.8 7.0 15.0 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Band_3_cyto PF07565.13 CDJ49544.1 - 4.7 6.9 17.4 6.7 6.4 17.4 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SKA1 PF07160.12 CDJ49544.1 - 4.7 7.0 24.7 5.7 6.7 24.7 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 APH PF01636.23 CDJ49544.1 - 5.7 6.8 11.8 6.6 6.6 11.8 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Spt20 PF12090.8 CDJ49545.1 - 1.2 8.7 7.5 1.3 8.5 7.5 1.1 1 0 0 1 1 1 0 Spt20 family FAM70 PF14967.6 CDJ49545.1 - 1.7 8.0 4.4 1.9 7.9 4.4 1.0 1 0 0 1 1 1 0 FAM70 protein MITF_TFEB_C_3_N PF15951.5 CDJ49545.1 - 2 9.0 11.6 0.23 12.1 7.2 1.6 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus TFIIA PF03153.13 CDJ49545.1 - 10 6.0 14.0 10 6.0 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ49546.1 - 0.0061 16.2 21.2 0.0061 16.2 21.2 5.7 4 3 1 5 5 5 1 Nuclear RNA-splicing-associated protein NAM-associated PF14303.6 CDJ49546.1 - 0.0091 16.7 17.9 0.0091 16.7 17.9 6.4 2 1 3 5 5 5 1 No apical meristem-associated C-terminal domain CNDH2_C PF16858.5 CDJ49546.1 - 2.4 8.0 37.0 0.27 11.1 8.3 3.4 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RNase_H2_suC PF08615.11 CDJ49546.1 - 2.5 8.3 16.5 0.73 10.0 0.6 3.3 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) ASC PF00858.24 CDJ49546.1 - 2.6 6.9 10.7 0.5 9.3 0.2 2.3 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel SID-1_RNA_chan PF13965.6 CDJ49546.1 - 3.6 5.9 18.1 0.51 8.7 2.7 2.5 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 MAM33 PF02330.16 CDJ49546.1 - 4.1 7.3 34.1 0.1 12.5 6.1 3.4 3 0 0 3 3 3 0 Mitochondrial glycoprotein Glyco_transf_8 PF01501.20 CDJ49546.1 - 7.2 6.1 8.4 1.3 8.5 1.7 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 8 Macoilin PF09726.9 CDJ49547.1 - 0.0034 16.0 13.4 0.0045 15.6 13.4 1.1 1 0 0 1 1 1 1 Macoilin family Ribosomal_60s PF00428.19 CDJ49547.1 - 0.026 15.1 10.0 0.026 15.1 10.0 2.8 2 1 0 2 2 2 0 60s Acidic ribosomal protein XRCC4 PF06632.12 CDJ49547.1 - 0.31 9.9 9.5 0.14 11.0 0.6 2.1 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4757 PF15949.5 CDJ49547.1 - 0.37 11.3 12.0 0.11 12.9 5.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) Apt1 PF10351.9 CDJ49547.1 - 0.41 9.5 13.3 0.012 14.5 6.2 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF3037 PF11236.8 CDJ49547.1 - 1.2 9.5 3.7 1 9.8 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Cwf_Cwc_15 PF04889.12 CDJ49547.1 - 2 8.1 9.0 0.61 9.8 2.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Band_3_cyto PF07565.13 CDJ49547.1 - 3.3 7.4 7.9 0.33 10.7 2.2 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF515 PF04415.12 CDJ49547.1 - 5.2 5.4 21.6 0.18 10.1 15.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF515) OAD_gamma PF04277.13 CDJ49547.1 - 6 7.5 11.5 1.2 9.8 1.7 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain SR-25 PF10500.9 CDJ49549.1 - 0.00033 20.3 31.4 0.00033 20.3 31.4 2.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4834 PF16118.5 CDJ49549.1 - 0.0016 19.4 11.6 0.0016 19.4 11.6 4.1 1 1 1 2 2 1 1 Domain of unknown function (DUF4834) Peptidase_S49_N PF08496.10 CDJ49549.1 - 0.0022 18.1 14.5 0.0022 18.1 14.5 2.2 2 0 0 2 2 2 1 Peptidase family S49 N-terminal Wzy_C PF04932.15 CDJ49549.1 - 0.0047 16.6 0.4 0.011 15.3 0.2 1.9 1 1 0 1 1 1 1 O-Antigen ligase CBP_BcsG PF11658.8 CDJ49549.1 - 0.0047 15.4 14.1 0.0047 15.4 14.1 2.1 1 1 0 2 2 1 1 Cellulose biosynthesis protein BcsG PI3K_1B_p101 PF10486.9 CDJ49549.1 - 0.024 12.4 29.5 0.038 11.8 29.5 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit O-antigen_lig PF13425.6 CDJ49549.1 - 0.065 12.0 20.3 1 8.1 20.1 2.0 1 1 0 1 1 1 0 O-antigen ligase like membrane protein PRCH PF03967.13 CDJ49549.1 - 0.075 13.3 1.6 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region DUF2981 PF11200.8 CDJ49549.1 - 0.087 12.6 12.3 0.11 12.2 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) CytochromB561_N PF09786.9 CDJ49549.1 - 0.11 11.4 34.2 0.16 11.0 34.2 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Hamartin PF04388.12 CDJ49549.1 - 0.78 8.3 40.5 1.1 7.8 40.5 1.3 1 0 0 1 1 1 0 Hamartin protein Bac_transf PF02397.16 CDJ49549.1 - 1.3 8.6 9.7 1.6 8.3 0.9 2.5 2 1 0 2 2 2 0 Bacterial sugar transferase DUF572 PF04502.13 CDJ49549.1 - 6.8 6.2 50.3 10 5.6 50.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SpoIIIAH PF12685.7 CDJ49549.1 - 7.5 6.3 44.1 5e+02 0.4 44.1 2.2 1 1 0 1 1 1 0 SpoIIIAH-like protein TFIIF_alpha PF05793.12 CDJ49549.1 - 8.2 4.9 38.6 11 4.5 38.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LMF1 PF06762.14 CDJ49550.1 - 8.6 5.3 11.4 10 5.1 11.4 1.0 1 0 0 1 1 1 0 Lipase maturation factor Mg_trans_NIPA PF05653.14 CDJ49552.1 - 7.1e-12 45.0 2.5 7.1e-12 45.0 2.5 1.9 1 1 1 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 CDJ49552.1 - 0.0017 18.5 2.1 0.0017 18.5 2.1 3.0 2 1 0 2 2 2 1 EamA-like transporter family TauE PF01925.19 CDJ49552.1 - 0.0033 17.1 0.0 0.0033 17.1 0.0 2.1 1 1 1 2 2 2 1 Sulfite exporter TauE/SafE DUF4383 PF14325.6 CDJ49552.1 - 0.019 15.2 0.5 0.019 15.2 0.5 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4383) YiaAB PF05360.14 CDJ49552.1 - 0.3 11.4 0.3 0.3 11.4 0.3 2.8 3 0 0 3 3 3 0 yiaA/B two helix domain DUF4131 PF13567.6 CDJ49552.1 - 0.64 9.7 0.0 0.64 9.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) SUIM_assoc PF16619.5 CDJ49553.1 - 0.00011 22.2 15.6 0.016 15.2 1.2 2.9 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ49553.1 - 0.0056 16.3 5.4 0.0056 16.3 5.4 2.7 2 1 1 3 3 3 1 Spt20 family Activator_LAG-3 PF11498.8 CDJ49553.1 - 0.4 9.6 28.9 0.055 12.4 2.7 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Dfp1_Him1_M PF08630.10 CDJ49553.1 - 0.77 10.0 5.4 3.9 7.7 0.7 2.4 2 0 0 2 2 2 0 Dfp1/Him1, central region Sin_N PF04801.13 CDJ49553.1 - 5.5 6.1 18.1 2 7.5 2.0 2.1 2 0 0 2 2 2 0 Sin-like protein conserved region BSP_II PF05432.11 CDJ49554.1 - 6.6 6.3 34.2 8.2 6.0 34.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RR_TM4-6 PF06459.12 CDJ49555.1 - 4.7 7.0 14.1 5.6 6.7 14.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.10 CDJ49556.1 - 0.23 10.8 25.0 0.27 10.6 25.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Endostatin PF06482.11 CDJ49556.1 - 0.29 10.6 17.1 0.36 10.2 17.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Presenilin PF01080.17 CDJ49556.1 - 1.1 8.0 26.4 1.4 7.6 26.4 1.1 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.12 CDJ49556.1 - 1.2 7.7 21.7 1.3 7.6 21.7 1.0 1 0 0 1 1 1 0 Hamartin protein CCSAP PF15748.5 CDJ49556.1 - 1.4 9.1 28.5 1.6 8.8 28.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FAM60A PF15396.6 CDJ49556.1 - 1.7 8.6 17.9 2.4 8.1 17.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A LAP1C PF05609.12 CDJ49556.1 - 3.1 6.8 21.0 3.6 6.6 21.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) AUX_IAA PF02309.16 CDJ49556.1 - 4 7.2 13.1 4.6 7.0 13.1 1.2 1 0 0 1 1 1 0 AUX/IAA family Asp-B-Hydro_N PF05279.11 CDJ49556.1 - 4.3 7.3 17.9 4.8 7.2 17.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC45 PF02724.14 CDJ49556.1 - 4.8 5.3 21.1 5.7 5.1 21.1 1.1 1 0 0 1 1 1 0 CDC45-like protein ORC6 PF05460.13 CDJ49556.1 - 6.2 6.0 22.7 6.9 5.8 22.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hid1 PF12722.7 CDJ49556.1 - 6.6 4.7 21.0 7.3 4.6 21.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4661 PF15576.6 CDJ49556.1 - 10 6.0 9.2 12 5.8 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Ribosomal_60s PF00428.19 CDJ49557.1 - 0.61 10.7 14.3 1.5 9.5 14.3 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3439 PF11921.8 CDJ49557.1 - 0.68 9.9 8.1 2.6 8.0 8.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Choline_kinase PF01633.20 CDJ49558.1 - 1.6e-29 103.1 4.3 4.1e-29 101.7 0.0 3.1 2 1 2 4 4 3 1 Choline/ethanolamine kinase APH PF01636.23 CDJ49558.1 - 3.4e-09 37.0 0.2 3.4e-09 37.0 0.2 3.5 2 1 1 3 3 2 1 Phosphotransferase enzyme family SR-25 PF10500.9 CDJ49558.1 - 5.7e-05 22.8 34.6 0.021 14.5 3.9 3.1 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein Trp_oprn_chp PF09534.10 CDJ49558.1 - 0.0018 18.1 18.7 0.0021 17.9 3.7 2.5 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RskA PF10099.9 CDJ49558.1 - 0.02 15.2 59.9 0.61 10.4 25.0 3.1 2 1 0 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ49558.1 - 0.029 14.4 81.3 0.45 10.4 43.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ49558.1 - 0.072 12.8 15.9 0.16 11.7 7.4 2.4 2 0 0 2 2 2 0 Connexin Velvet PF11754.8 CDJ49558.1 - 0.088 12.7 31.1 0.66 9.9 9.8 2.3 2 0 0 2 2 2 0 Velvet factor DUF2207 PF09972.9 CDJ49558.1 - 0.16 10.7 4.7 2.3 6.9 1.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SID-1_RNA_chan PF13965.6 CDJ49558.1 - 0.56 8.5 8.2 1.2 7.4 1.0 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 CDJ49558.1 - 0.71 8.8 25.5 0.96 8.4 11.3 2.2 2 0 0 2 2 2 0 Solute carrier family 12 FAM91_C PF14648.6 CDJ49558.1 - 0.9 8.3 14.3 0.37 9.6 1.8 2.3 2 0 0 2 2 2 0 FAM91 C-terminus TRAP_alpha PF03896.16 CDJ49558.1 - 2 7.5 15.4 1.6 7.9 6.3 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit INSIG PF07281.12 CDJ49558.1 - 2.8 7.5 11.1 2 8.0 1.7 2.6 2 1 0 2 2 2 0 Insulin-induced protein (INSIG) DUF572 PF04502.13 CDJ49558.1 - 3.3 7.2 25.1 2.5 7.6 8.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) IHABP4_N PF16174.5 CDJ49558.1 - 3.4 8.2 47.3 0.83 10.2 20.8 3.1 3 0 0 3 3 3 0 Intracellular hyaluronan-binding protein 4 N-terminal MRI PF15325.6 CDJ49558.1 - 5.1 8.2 31.4 0.24 12.5 5.3 3.3 3 0 0 3 3 3 0 Modulator of retrovirus infection CrgA PF06781.12 CDJ49558.1 - 5.2 7.2 7.9 11 6.2 1.3 3.0 3 0 0 3 3 3 0 Cell division protein CrgA THOC2_N PF16134.5 CDJ49558.1 - 5.6 5.5 26.8 0.34 9.5 10.4 2.2 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus GT87 PF09594.10 CDJ49559.1 - 0.0096 15.6 7.8 0.29 10.8 3.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 87 RskA PF10099.9 CDJ49559.1 - 0.38 11.0 40.0 0.22 11.8 14.4 2.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA RIFIN PF02009.16 CDJ49559.1 - 0.51 10.2 11.3 0.74 9.7 11.3 1.2 1 0 0 1 1 1 0 Rifin Activator_LAG-3 PF11498.8 CDJ49559.1 - 2 7.3 39.7 0.17 10.8 25.0 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 RskA PF10099.9 CDJ49560.1 - 0.0014 18.9 16.7 0.0055 17.0 5.6 10.6 4 4 3 7 7 7 2 Anti-sigma-K factor rskA NAM-associated PF14303.6 CDJ49560.1 - 0.011 16.4 5.0 0.011 16.4 5.0 10.4 4 3 3 8 8 8 0 No apical meristem-associated C-terminal domain PAP1 PF08601.10 CDJ49560.1 - 2.9 7.5 0.0 2.9 7.5 0.0 7.4 3 3 3 6 6 6 0 Transcription factor PAP1 SseC PF04888.12 CDJ49561.1 - 0.013 15.1 0.6 0.013 15.1 0.6 9.9 6 2 1 7 7 7 0 Secretion system effector C (SseC) like family PAP1 PF08601.10 CDJ49561.1 - 0.083 12.6 0.0 0.083 12.6 0.0 9.1 4 3 3 8 8 8 0 Transcription factor PAP1 RRN3 PF05327.11 CDJ49562.1 - 1.4e-36 126.2 1.4 1.4e-36 126.2 1.4 11.2 8 2 0 8 8 8 1 RNA polymerase I specific transcription initiation factor RRN3 PBP PF01161.20 CDJ49563.1 - 9.8e-18 64.7 0.9 9.8e-18 64.7 0.9 2.4 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein DUF3223 PF11523.8 CDJ49563.1 - 1.3e-07 32.4 0.0 5.3e-07 30.4 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) Med15 PF09606.10 CDJ49563.1 - 0.00026 19.9 4.6 0.00026 19.9 4.6 8.2 6 2 1 7 7 7 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4667 PF15700.5 CDJ49563.1 - 0.0097 16.0 0.6 0.0097 16.0 0.6 8.8 6 3 2 8 8 8 1 Domain of unknown function (DUF4667) HhH-GPD PF00730.25 CDJ49564.1 - 9.9e-06 26.0 0.0 2e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein CRT10 PF08728.10 CDJ49564.1 - 3 5.9 10.5 3.8 5.6 10.5 1.2 1 0 0 1 1 1 0 CRT10 RabGAP-TBC PF00566.18 CDJ49564.1 - 5.6 6.5 10.5 11 5.7 10.5 1.4 1 0 0 1 1 1 0 Rab-GTPase-TBC domain DUF508 PF04370.12 CDJ49564.1 - 8.8 6.1 21.9 8.7 6.1 4.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Presenilin PF01080.17 CDJ49565.1 - 0.00013 20.9 13.2 0.00013 20.9 13.2 2.1 2 0 0 2 2 2 1 Presenilin MCM_bind PF09739.9 CDJ49565.1 - 0.00028 19.5 8.8 0.00028 19.5 8.8 2.1 2 0 0 2 2 2 1 Mini-chromosome maintenance replisome factor CPSF100_C PF13299.6 CDJ49565.1 - 0.00042 20.5 10.9 0.00042 20.5 10.9 2.9 2 1 1 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal SpoIIIAH PF12685.7 CDJ49565.1 - 0.00066 19.6 6.4 0.00066 19.6 6.4 2.3 2 1 0 2 2 1 1 SpoIIIAH-like protein DUF913 PF06025.12 CDJ49565.1 - 0.0019 17.3 5.0 0.0019 17.3 5.0 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) RNA_pol_A_CTD PF03118.15 CDJ49565.1 - 0.013 15.3 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain ANAPC_CDC26 PF10471.9 CDJ49565.1 - 0.041 14.7 9.4 0.041 14.7 9.4 4.2 3 1 1 4 4 2 0 Anaphase-promoting complex APC subunit CDC26 RNA_pol_L PF01193.24 CDJ49565.1 - 0.09 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2151 PF10221.9 CDJ49565.1 - 0.22 10.1 20.8 0.067 11.8 7.2 2.0 2 0 0 2 2 2 0 Cell cycle and development regulator Piezo_RRas_bdg PF12166.8 CDJ49565.1 - 0.27 10.5 9.1 0.082 12.2 0.5 2.0 2 0 0 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain Adaptin_binding PF10199.9 CDJ49565.1 - 0.55 10.9 28.3 0.035 14.7 12.0 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SMYLE_N PF18615.1 CDJ49565.1 - 3.1 7.3 21.1 1.9 7.9 7.6 2.2 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain NPR3 PF03666.13 CDJ49565.1 - 3.6 6.3 27.5 0.2 10.4 15.6 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Otopetrin PF03189.13 CDJ49565.1 - 4.1 6.1 14.5 0.46 9.2 7.5 2.0 2 0 0 2 2 2 0 Otopetrin SLC12 PF03522.15 CDJ49565.1 - 6 5.8 31.9 2.9 6.8 3.5 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Fanconi_A PF03511.14 CDJ49566.1 - 0.23 11.4 0.4 9.7 6.2 0.1 2.5 2 0 0 2 2 2 0 Fanconi anaemia group A protein SPX PF03105.19 CDJ49570.1 - 0.0065 16.4 3.1 0.0065 16.4 3.1 2.8 2 1 0 2 2 2 1 SPX domain Shisa PF13908.6 CDJ49570.1 - 3.2 8.0 18.5 0.74 10.0 2.6 3.8 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Lin-8 PF03353.15 CDJ49570.1 - 4.1 6.9 14.1 2.4 7.6 3.6 3.2 2 1 1 3 3 3 0 Ras-mediated vulval-induction antagonist DUF572 PF04502.13 CDJ49570.1 - 6.4 6.3 17.3 0.66 9.5 2.1 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF572) Ank_2 PF12796.7 CDJ49571.1 - 2.3e-10 40.9 16.1 0.022 15.3 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ49571.1 - 1.2e-06 28.7 5.4 0.061 13.8 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 CDJ49571.1 - 1.2e-06 28.7 7.2 0.029 14.7 0.0 4.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ49571.1 - 2.1e-05 25.0 13.7 0.018 15.6 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Activator_LAG-3 PF11498.8 CDJ49571.1 - 7.8e-05 21.8 32.9 7.8e-05 21.8 32.9 15.1 12 4 2 15 15 15 2 Transcriptional activator LAG-3 LRR_8 PF13855.6 CDJ49571.1 - 0.00013 21.6 13.4 0.00026 20.7 7.4 2.8 2 1 0 2 2 2 1 Leucine rich repeat SR-25 PF10500.9 CDJ49571.1 - 0.0002 21.1 4.4 0.0002 21.1 4.4 20.1 15 5 7 22 22 22 3 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ49571.1 - 0.00041 20.0 11.2 0.00041 20.0 11.2 18.3 12 5 1 14 14 14 5 Spt20 family Ank_3 PF13606.6 CDJ49571.1 - 0.0045 17.4 14.1 0.089 13.4 0.0 6.5 8 0 0 8 8 8 1 Ankyrin repeat LRR_4 PF12799.7 CDJ49571.1 - 0.77 10.3 11.1 0.91 10.0 6.6 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) SR-25 PF10500.9 CDJ49572.1 - 0.0065 16.1 24.1 0.0065 16.1 24.1 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein MAP7 PF05672.11 CDJ49572.1 - 0.024 14.3 42.7 0.1 12.3 19.3 2.1 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family MDM1 PF15501.6 CDJ49572.1 - 0.12 11.5 44.8 0.27 10.3 23.3 2.0 2 0 0 2 2 2 0 Nuclear protein MDM1 BORG_CEP PF14957.6 CDJ49572.1 - 0.17 13.0 25.9 0.08 14.1 11.0 2.1 2 0 0 2 2 2 0 Cdc42 effector CNDH2_C PF16858.5 CDJ49572.1 - 0.61 9.9 23.8 0.85 9.4 5.2 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term FAM176 PF14851.6 CDJ49572.1 - 1.2 8.8 16.1 2.5 7.7 4.6 2.4 2 0 0 2 2 2 0 FAM176 family DUF2052 PF09747.9 CDJ49572.1 - 1.3 9.1 26.8 0.46 10.6 4.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) MAT1 PF06391.13 CDJ49572.1 - 2.8 7.7 30.0 1.4 8.7 8.7 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Peptidase_S49_N PF08496.10 CDJ49572.1 - 6.1 6.9 20.0 1.1 9.3 4.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CIAPIN1 PF05093.13 CDJ49572.1 - 6.3 7.4 14.9 11 6.6 5.5 2.4 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis SpoIIP PF07454.11 CDJ49572.1 - 7.3 6.0 30.2 1.8 7.9 9.7 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Otopetrin PF03189.13 CDJ49573.1 - 0.0029 16.5 0.0 1.3 7.8 0.0 3.9 3 1 0 3 3 3 1 Otopetrin Phosducin PF02114.16 CDJ49574.1 - 0.51 9.2 9.1 0.82 8.6 9.1 1.4 1 0 0 1 1 1 0 Phosducin Cyt_bd_oxida_II PF02322.15 CDJ49574.1 - 0.82 9.0 21.0 1.2 8.4 21.0 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF2722 PF10846.8 CDJ49575.1 - 2.7e-07 29.9 4.4 3.4e-07 29.6 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ49575.1 - 4.1e-06 26.6 15.3 6.6e-06 25.9 15.3 1.5 1 0 0 1 1 1 1 Spt20 family WBP-1 PF11669.8 CDJ49575.1 - 0.036 14.7 4.3 0.081 13.6 4.3 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 Band_3_cyto PF07565.13 CDJ49575.1 - 0.086 12.6 2.1 0.13 12.1 2.1 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Dpy19 PF10034.9 CDJ49575.1 - 0.77 7.9 5.4 1 7.5 5.4 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation UPF0560 PF10577.9 CDJ49575.1 - 3.4 6.1 15.3 6.8 5.1 15.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Sporozoite_P67 PF05642.11 CDJ49575.1 - 3.4 5.6 17.6 4.7 5.2 17.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VKG_Carbox PF05090.14 CDJ49575.1 - 3.5 6.4 3.5 4.9 5.9 3.5 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase V_ATPase_I PF01496.19 CDJ49575.1 - 5.6 4.7 7.7 9.1 4.1 7.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5427 PF10310.9 CDJ49577.1 - 0.0045 16.0 0.3 0.0045 16.0 0.3 4.9 3 2 1 4 4 4 1 Family of unknown function (DUF5427) SKG6 PF08693.10 CDJ49577.1 - 3 7.4 4.9 5.8 6.4 4.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PIP5K PF01504.18 CDJ49579.1 - 1.8e-35 122.5 71.3 9.2e-20 71.0 0.1 8.0 5 2 1 6 6 6 3 Phosphatidylinositol-4-phosphate 5-Kinase DUF2722 PF10846.8 CDJ49579.1 - 0.00067 18.7 0.5 0.00067 18.7 0.5 7.2 6 1 1 7 7 7 4 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ49579.1 - 0.43 10.9 0.0 0.43 10.9 0.0 11.1 5 2 5 10 10 10 0 Anti-sigma-K factor rskA IPK PF03770.16 CDJ49580.1 - 3e-11 43.6 0.8 3e-11 43.6 0.8 3.4 2 2 0 2 2 2 1 Inositol polyphosphate kinase DUF755 PF05501.11 CDJ49580.1 - 0.0063 16.8 21.7 0.0063 16.8 21.7 8.5 5 2 2 7 7 7 1 Domain of unknown function (DUF755) CBM_20 PF00686.19 CDJ49581.1 - 1e-17 63.8 0.0 1.9e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain Glyco_transf_20 PF00982.21 CDJ49581.1 - 4.5e-07 28.9 0.0 3.7e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 20 RskA PF10099.9 CDJ49581.1 - 0.15 12.3 12.1 0.079 13.3 6.7 2.0 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ49581.1 - 1.4 8.4 12.5 9.4 5.8 13.0 1.8 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ49581.1 - 5.8 5.7 10.1 12 4.7 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BAF1_ABF1 PF04684.13 CDJ49582.1 - 0.22 10.5 37.7 0.27 10.2 37.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SART-1 PF03343.13 CDJ49582.1 - 0.49 8.9 38.4 0.57 8.7 38.4 1.0 1 0 0 1 1 1 0 SART-1 family Pinin_SDK_memA PF04696.13 CDJ49582.1 - 1.9 8.5 51.2 0.33 11.0 30.4 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region PTPRCAP PF15713.5 CDJ49582.1 - 7.3 6.9 37.4 1 9.7 22.2 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Vps4_C PF09336.10 CDJ49583.1 - 4.7e-05 23.3 0.0 0.00012 22.0 0.0 1.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain DEAD PF00270.29 CDJ49585.1 - 1.3e-43 148.8 0.0 5.3e-43 146.8 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ49585.1 - 1.5e-30 105.8 0.0 9.2e-30 103.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ49585.1 - 1.5e-06 28.3 0.0 1.5e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CDJ49585.1 - 0.0015 17.9 1.0 0.0027 17.0 0.0 1.8 2 0 0 2 2 2 1 SecA DEAD-like domain zf-CCHC PF00098.23 CDJ49585.1 - 4.5 7.5 8.6 0.35 11.0 3.6 1.8 2 0 0 2 2 2 0 Zinc knuckle DUF4834 PF16118.5 CDJ49586.1 - 3.4 8.7 5.6 15 6.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Galactosyl_T PF01762.21 CDJ49587.1 - 2.8e-27 95.8 0.0 3.9e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 CDJ49588.1 - 8.4e-49 166.0 0.0 1e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 CDJ49588.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Fringe-like Glyco_transf_21 PF13506.6 CDJ49588.1 - 0.1 12.1 0.0 0.65 9.5 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 21 DUF4834 PF16118.5 CDJ49589.1 - 0.0002 22.3 9.6 0.0016 19.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 CDJ49589.1 - 0.00029 21.0 1.3 0.0004 20.5 1.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Tmemb_9 PF05434.11 CDJ49589.1 - 0.0033 17.3 2.0 0.0033 17.3 2.0 2.3 2 0 0 2 2 2 1 TMEM9 FHIPEP PF00771.20 CDJ49589.1 - 0.0063 15.1 2.5 0.0063 15.1 2.5 1.9 1 1 1 2 2 1 1 FHIPEP family OSTbeta PF15048.6 CDJ49589.1 - 0.0065 16.6 1.2 0.0065 16.6 1.2 2.2 2 0 0 2 2 2 1 Organic solute transporter subunit beta protein DUF2244 PF10003.9 CDJ49589.1 - 0.0076 15.9 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) Pex24p PF06398.11 CDJ49589.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF4220 PF13968.6 CDJ49589.1 - 0.011 15.1 0.4 0.015 14.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Wzy_C PF04932.15 CDJ49589.1 - 0.03 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase Phage_holin_3_6 PF07332.11 CDJ49589.1 - 0.039 14.0 5.8 0.25 11.4 7.0 1.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III FA_desaturase PF00487.24 CDJ49589.1 - 0.099 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase GPI2 PF06432.11 CDJ49589.1 - 0.13 11.7 0.9 0.19 11.2 0.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase SID-1_RNA_chan PF13965.6 CDJ49589.1 - 0.44 8.9 3.6 0.83 8.0 3.6 1.5 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Mem_trans PF03547.18 CDJ49589.1 - 1.1 7.5 4.9 0.28 9.5 1.4 1.8 1 1 1 2 2 2 0 Membrane transport protein YfhO PF09586.10 CDJ49589.1 - 4.2 5.5 8.6 0.073 11.3 1.3 1.6 1 1 1 2 2 2 0 Bacterial membrane protein YfhO Ac76 PF05814.11 CDJ49589.1 - 7.7 6.6 12.0 1e+02 3.0 12.4 2.2 1 1 0 1 1 1 0 Orf76 (Ac76) DUF5523 PF17661.1 CDJ49589.1 - 7.9 6.1 16.3 10 5.7 16.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF4131 PF13567.6 CDJ49589.1 - 8.1 6.1 6.1 10 5.8 5.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF572 PF04502.13 CDJ49590.1 - 2.1 7.9 12.2 2.4 7.7 12.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) HA2 PF04408.23 CDJ49591.1 - 6.9e-20 71.4 0.0 3.3e-19 69.2 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDJ49591.1 - 2.3e-13 50.5 0.0 4.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TPR_8 PF13181.6 CDJ49592.1 - 7.3e-07 28.9 0.6 0.0026 17.8 0.3 4.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ49592.1 - 1.8e-06 28.4 0.3 4.4e-05 23.9 0.3 5.5 7 0 0 7 7 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ49592.1 - 8.7e-06 25.5 3.9 0.0078 16.3 1.1 4.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ49592.1 - 1.7e-05 24.4 4.1 0.044 13.6 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ49592.1 - 0.00012 21.8 1.3 13 6.1 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.29 CDJ49592.1 - 0.0016 18.2 0.2 0.0083 15.9 0.2 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ49592.1 - 0.0048 17.2 0.1 0.028 14.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain TPR_11 PF13414.6 CDJ49592.1 - 0.01 15.5 0.7 15 5.4 0.1 4.0 4 0 0 4 4 4 0 TPR repeat T2SSE PF00437.20 CDJ49592.1 - 0.013 14.6 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 CDJ49592.1 - 0.019 15.3 1.0 0.18 12.1 1.0 2.6 1 1 0 1 1 1 0 AAA domain TPR_12 PF13424.6 CDJ49592.1 - 0.075 13.3 0.1 0.075 13.3 0.1 4.3 3 1 2 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ49592.1 - 0.25 12.3 0.0 0.64 11.0 0.9 8.5 8 1 1 9 9 6 0 Tetratricopeptide repeat AAA_33 PF13671.6 CDJ49592.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.6 3 0 0 3 3 1 0 AAA domain TPR_9 PF13371.6 CDJ49592.1 - 0.31 11.2 0.0 0.31 11.2 0.0 4.4 6 0 0 6 6 3 0 Tetratricopeptide repeat Ndc1_Nup PF09531.10 CDJ49592.1 - 0.6 8.7 10.5 1.3 7.6 10.5 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cryptochrome_C PF12546.8 CDJ49592.1 - 0.91 10.1 16.3 0.12 12.9 0.7 3.6 2 1 1 3 3 3 0 Blue/Ultraviolet sensing protein C terminal SAPS PF04499.15 CDJ49592.1 - 1.3 7.7 9.8 2.3 6.9 9.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRP14 PF15459.6 CDJ49592.1 - 4.2 8.0 10.9 12 6.6 2.8 3.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 CDC45 PF02724.14 CDJ49592.1 - 4.7 5.4 17.5 13 3.9 17.5 1.8 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 CDJ49592.1 - 5.6 3.9 13.1 8.9 3.3 13.1 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF31 PF01732.16 CDJ49593.1 - 0.16 11.5 4.7 0.3 10.6 4.7 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) DUF1467 PF07330.12 CDJ49594.1 - 3.5 7.6 11.3 19 5.2 3.7 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) RskA PF10099.9 CDJ49595.1 - 0.054 13.8 0.0 0.054 13.8 0.0 56.8 19 12 18 42 42 42 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ49595.1 - 2.2 8.4 0.0 0.045 13.8 1.3 60.8 47 10 8 55 55 55 0 Unstructured region C-term to UIM in Ataxin3 zf-CCHC_3 PF13917.6 CDJ49596.1 - 8.2e-18 64.1 3.6 2.4e-17 62.6 3.6 1.9 1 0 0 1 1 1 1 Zinc knuckle Bestrophin PF01062.21 CDJ49596.1 - 0.00018 21.0 0.1 0.00018 21.0 0.1 2.8 3 0 0 3 3 3 1 Bestrophin, RFP-TM, chloride channel DUF755 PF05501.11 CDJ49596.1 - 0.00083 19.6 25.3 0.00083 19.6 25.3 15.1 6 2 2 8 8 8 1 Domain of unknown function (DUF755) DUF1275 PF06912.11 CDJ49596.1 - 1.1 9.2 5.1 2.9 7.8 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Abhydrolase_9_N PF15420.6 CDJ49596.1 - 1.7 8.6 14.8 0.69 9.9 8.8 2.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus PGK PF00162.19 CDJ49597.1 - 6.8e-112 374.1 2.3 6.1e-64 216.3 0.1 2.3 2 1 0 2 2 2 2 Phosphoglycerate kinase RskA PF10099.9 CDJ49597.1 - 0.011 16.0 6.3 0.011 16.0 6.3 3.6 2 2 1 3 3 3 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ49597.1 - 0.015 15.3 13.9 0.03 14.3 13.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FlgH PF02107.16 CDJ49597.1 - 0.026 14.1 0.1 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 Flagellar L-ring protein POT1PC PF16686.5 CDJ49597.1 - 0.091 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Activator_LAG-3 PF11498.8 CDJ49597.1 - 0.69 8.8 17.5 0.13 11.2 5.7 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF3446 PF11928.8 CDJ49597.1 - 5.7 7.3 17.7 0.13 12.6 5.9 3.2 3 0 0 3 3 3 0 Early growth response N-terminal domain DNA_pol3_delta2 PF13177.6 CDJ49598.1 - 3.1e-10 40.1 0.0 8.9e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CDJ49598.1 - 0.0036 17.2 0.0 0.008 16.1 0.0 1.6 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 CDJ49598.1 - 0.016 15.6 6.1 0.31 11.4 6.1 2.5 1 1 0 1 1 1 0 AAA ATPase domain Sec3_C PF09763.9 CDJ49599.1 - 0.18 10.1 1.3 0.18 10.1 1.3 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF1635 PF07795.11 CDJ49599.1 - 0.42 10.4 7.3 0.58 10.0 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Apt1 PF10351.9 CDJ49599.1 - 0.7 8.7 10.7 0.74 8.6 10.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain HSD3 PF15244.6 CDJ49599.1 - 0.83 9.1 7.3 0.88 9.0 7.3 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 BUD22 PF09073.10 CDJ49599.1 - 0.84 8.9 18.7 0.95 8.7 18.7 1.0 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 CDJ49599.1 - 1.8 8.3 8.8 2.3 7.9 8.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SPX PF03105.19 CDJ49599.1 - 2.9 7.7 18.0 3.5 7.5 18.0 1.0 1 0 0 1 1 1 0 SPX domain MAP65_ASE1 PF03999.12 CDJ49599.1 - 3.5 6.2 4.9 3.6 6.2 4.9 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Peroxin-3 PF04882.12 CDJ49599.1 - 4.7 6.1 12.2 5.9 5.8 12.2 1.2 1 0 0 1 1 1 0 Peroxin-3 Presenilin PF01080.17 CDJ49599.1 - 4.7 5.9 8.2 5.1 5.7 8.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 CDJ49599.1 - 5.6 5.7 6.1 6 5.6 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOG2 PF10428.9 CDJ49599.1 - 6.5 5.8 22.7 7.4 5.7 22.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein VIR_N PF15912.5 CDJ49600.1 - 1.6 8.2 18.4 1.9 8.0 18.4 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal RR_TM4-6 PF06459.12 CDJ49600.1 - 3.7 7.3 27.9 4 7.2 27.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 CDJ49600.1 - 3.8 7.2 23.4 4.1 7.1 23.4 1.0 1 0 0 1 1 1 0 AAA domain FAM60A PF15396.6 CDJ49600.1 - 4.3 7.3 20.5 5.5 6.9 20.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A cwf18 PF08315.12 CDJ49600.1 - 6.6 7.4 22.1 7.6 7.2 22.1 1.2 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Cnd1 PF12717.7 CDJ49601.1 - 5.5e-06 26.5 0.4 0.067 13.2 0.0 4.3 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 SR-25 PF10500.9 CDJ49601.1 - 0.00025 20.7 9.7 0.00025 20.7 9.7 12.1 10 3 1 11 11 9 3 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ49601.1 - 0.0007 18.7 17.3 0.0007 18.7 17.3 14.0 9 3 2 13 13 5 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ49601.1 - 0.0018 18.4 26.2 0.0018 18.4 26.2 10.7 2 2 8 10 10 4 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ49601.1 - 0.0025 17.5 25.7 0.0025 17.5 25.7 13.1 11 1 2 13 13 10 5 Spt20 family Apc15p PF05841.11 CDJ49601.1 - 0.0028 18.5 13.1 0.0028 18.5 13.1 13.5 11 4 1 12 12 6 1 Apc15p protein Peptidase_S49_N PF08496.10 CDJ49601.1 - 0.0041 17.2 1.2 0.0041 17.2 1.2 8.3 9 0 0 9 9 8 1 Peptidase family S49 N-terminal SARAF PF06682.12 CDJ49601.1 - 0.0043 16.7 0.1 0.0043 16.7 0.1 11.7 11 1 1 12 12 10 1 SOCE-associated regulatory factor of calcium homoeostasis PNISR PF15996.5 CDJ49601.1 - 0.0062 16.8 7.3 0.0062 16.8 7.3 10.4 9 2 1 10 10 7 2 Arginine/serine-rich protein PNISR HEAT PF02985.22 CDJ49601.1 - 0.071 13.4 8.9 37 4.9 0.0 7.2 6 0 0 6 6 6 0 HEAT repeat Spore_YhcN_YlaJ PF09580.10 CDJ49601.1 - 0.19 11.8 0.0 0.19 11.8 0.0 7.1 3 2 1 4 4 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 2-Hacid_dh_C PF02826.19 CDJ49603.1 - 1.4 8.3 4.9 2.9 7.2 4.9 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rieske PF00355.26 CDJ49604.1 - 2.2e-05 24.3 0.0 4.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF2722 PF10846.8 CDJ49604.1 - 0.00051 19.1 2.3 0.00051 19.1 2.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Pyr_redox_2 PF07992.14 CDJ49604.1 - 0.0011 18.3 0.3 0.0022 17.3 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDJ49604.1 - 0.0037 17.5 2.9 0.0071 16.5 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CDJ49604.1 - 0.0051 16.1 1.0 0.01 15.1 1.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDJ49604.1 - 0.01 15.1 0.2 0.01 15.1 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain DDHD PF02862.17 CDJ49604.1 - 0.015 15.5 0.7 0.016 15.4 0.7 1.1 1 0 0 1 1 1 0 DDHD domain Pyr_redox PF00070.27 CDJ49604.1 - 0.18 12.4 0.3 0.33 11.5 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ49604.1 - 0.28 10.2 8.0 0.21 10.6 0.9 2.1 2 0 0 2 2 2 0 FAD binding domain Presenilin PF01080.17 CDJ49604.1 - 0.74 8.5 11.0 0.95 8.2 11.0 1.1 1 0 0 1 1 1 0 Presenilin DUF2076 PF09849.9 CDJ49604.1 - 1.2 9.2 29.7 1.6 8.7 29.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RskA PF10099.9 CDJ49604.1 - 1.8 8.8 22.2 7.3 6.8 22.2 1.8 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Baculo_PP31 PF05311.11 CDJ49604.1 - 3.2 7.2 6.9 4.4 6.7 6.9 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF4770 PF15994.5 CDJ49604.1 - 3.4 7.9 10.5 1.3 9.2 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Neur_chan_memb PF02932.16 CDJ49604.1 - 7.4 6.5 9.2 11 6.1 9.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 CDJ49604.1 - 8.1 5.7 17.2 11 5.3 17.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2722 PF10846.8 CDJ49605.1 - 0.0029 16.6 3.7 0.0029 16.6 3.7 10.3 8 4 1 9 9 9 3 Protein of unknown function (DUF2722) DUF755 PF05501.11 CDJ49605.1 - 0.003 17.8 21.6 0.003 17.8 21.6 14.2 14 2 1 15 15 15 1 Domain of unknown function (DUF755) DUF4776 PF16003.5 CDJ49606.1 - 1 8.3 52.6 0.2 10.6 34.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) DUF2232 PF09991.9 CDJ49608.1 - 0.37 9.9 0.3 0.62 9.2 0.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) Ins145_P3_rec PF08709.11 CDJ49608.1 - 0.49 9.6 5.1 0.6 9.3 0.3 2.3 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor YajC PF02699.15 CDJ49608.1 - 9.3 6.2 7.8 21 5.1 7.8 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit ANAPC4_WD40 PF12894.7 CDJ49611.1 - 4e-13 49.5 0.0 4.6e-06 26.8 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ49611.1 - 1.7e-07 31.8 0.1 0.56 11.2 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat cwf18 PF08315.12 CDJ49611.1 - 0.00026 21.7 4.4 0.0009 19.9 4.4 1.9 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor eIF-3_zeta PF05091.12 CDJ49611.1 - 0.0019 17.3 5.9 0.0026 16.8 5.9 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ge1_WD40 PF16529.5 CDJ49611.1 - 0.0045 16.0 0.0 1.1 8.2 0.0 2.8 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4746 PF15928.5 CDJ49611.1 - 0.028 13.8 1.2 0.047 13.1 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BBS2_Mid PF14783.6 CDJ49611.1 - 0.056 13.5 0.0 13 5.9 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Suf PF05843.14 CDJ49611.1 - 0.087 12.8 13.2 0.22 11.5 13.2 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AF-4 PF05110.13 CDJ49611.1 - 0.12 10.5 18.7 0.26 9.3 18.7 1.6 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Coilin_N PF15862.5 CDJ49611.1 - 0.12 12.2 7.0 0.27 11.1 7.0 1.5 1 0 0 1 1 1 0 Coilin N-terminus Neur_chan_memb PF02932.16 CDJ49611.1 - 0.12 12.4 5.7 0.28 11.2 5.7 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ49611.1 - 0.14 10.9 8.0 0.32 9.7 8.0 1.6 1 0 0 1 1 1 0 Presenilin MecA PF05389.12 CDJ49611.1 - 0.16 11.6 3.2 0.34 10.5 3.2 1.5 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) PAT1 PF09770.9 CDJ49611.1 - 0.17 10.1 19.8 0.26 9.5 19.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 CDJ49611.1 - 0.28 10.7 38.8 0.6 9.7 38.8 1.4 1 0 0 1 1 1 0 Spt20 family CLN3 PF02487.17 CDJ49611.1 - 0.49 9.4 3.4 0.78 8.7 3.4 1.2 1 0 0 1 1 1 0 CLN3 protein EPL1 PF10513.9 CDJ49611.1 - 0.52 10.7 8.2 1.1 9.7 8.2 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF3408 PF11888.8 CDJ49611.1 - 0.72 10.0 8.5 1.8 8.7 8.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Connexin PF00029.19 CDJ49611.1 - 0.91 9.2 3.9 1.4 8.6 3.9 1.2 1 0 0 1 1 1 0 Connexin RPA43_OB PF17875.1 CDJ49611.1 - 0.94 10.1 6.1 2.7 8.6 6.1 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I FAM176 PF14851.6 CDJ49611.1 - 1.1 8.9 2.9 2.2 7.9 2.9 1.4 1 0 0 1 1 1 0 FAM176 family DUF3464 PF11947.8 CDJ49611.1 - 1.2 8.9 9.2 3.6 7.3 9.2 1.9 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SpoIIP PF07454.11 CDJ49611.1 - 1.5 8.2 9.6 2.3 7.6 9.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) V_ATPase_I PF01496.19 CDJ49611.1 - 4.4 5.1 10.5 6.3 4.6 10.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OATP PF03137.20 CDJ49611.1 - 5.7 5.1 6.0 8.8 4.5 6.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TERB2 PF15101.6 CDJ49611.1 - 7.3 6.6 14.3 13 5.7 14.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Lin-8 PF03353.15 CDJ49611.1 - 7.9 5.9 18.7 19 4.7 18.7 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PIP5K PF01504.18 CDJ49611.1 - 8.6 5.5 9.0 15 4.7 9.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Prominin PF05478.11 CDJ49612.1 - 3.4 5.5 10.1 3.6 5.4 10.1 1.1 1 0 0 1 1 1 0 Prominin BAF1_ABF1 PF04684.13 CDJ49612.1 - 8.6 5.3 26.5 10 5.0 26.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Brr6_like_C_C PF10104.9 CDJ49613.1 - 1.9e-21 76.3 0.0 1.9e-21 76.3 0.0 3.1 5 0 0 5 5 5 1 Di-sulfide bridge nucleocytoplasmic transport domain Presenilin PF01080.17 CDJ49613.1 - 0.0018 17.2 5.5 0.0018 17.2 5.5 3.9 3 1 1 4 4 4 1 Presenilin Exonuc_VII_L PF02601.15 CDJ49613.1 - 0.46 10.0 48.5 0.085 12.4 12.4 3.1 3 0 0 3 3 3 0 Exonuclease VII, large subunit OATP PF03137.20 CDJ49613.1 - 5.8 5.1 22.2 0.026 12.8 0.5 3.8 3 1 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF4179 PF13786.6 CDJ49613.1 - 9.1 6.8 12.0 17 6.0 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Sua5_yciO_yrdC PF01300.18 CDJ49614.1 - 1e-16 61.0 4.6 9.2e-12 44.8 0.1 3.6 4 0 0 4 4 4 3 Telomere recombination SUA5 PF03481.13 CDJ49614.1 - 1.3e-08 35.4 15.6 2.5e-08 34.5 10.7 3.4 2 1 0 2 2 2 1 Putative GTP-binding controlling metal-binding RskA PF10099.9 CDJ49614.1 - 3.8e-06 27.3 7.5 3.8e-06 27.3 7.5 6.7 1 1 2 5 5 2 2 Anti-sigma-K factor rskA AF-4 PF05110.13 CDJ49614.1 - 0.00013 20.2 23.0 0.00013 20.2 23.0 3.7 3 1 0 3 3 2 1 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ49614.1 - 0.00032 20.4 8.4 0.00032 20.4 8.4 3.9 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ49614.1 - 0.0056 16.3 6.9 0.0056 16.3 6.9 3.5 2 1 0 2 2 1 1 Spt20 family SPX PF03105.19 CDJ49614.1 - 0.13 12.1 38.4 2 8.2 16.8 3.6 1 1 1 2 2 2 0 SPX domain AAA_23 PF13476.6 CDJ49614.1 - 0.14 12.6 15.9 7.2 7.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain ART-PolyVal PF18760.1 CDJ49614.1 - 0.6 11.1 6.7 0.32 12.0 2.2 2.5 2 0 0 2 2 2 0 ADP-Ribosyltransferase in polyvalent proteins PAT1 PF09770.9 CDJ49614.1 - 1.7 6.8 30.7 0.92 7.7 18.9 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RCR PF12273.8 CDJ49614.1 - 2.2 9.0 9.2 13 6.5 3.7 2.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red UPF0564 PF10595.9 CDJ49614.1 - 4.8 6.1 30.9 3.8 6.5 18.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 XAP5 PF04921.14 CDJ49614.1 - 5.2 6.8 14.1 3.1 7.6 7.2 2.6 2 0 0 2 2 2 0 XAP5, circadian clock regulator rRNA_processing PF08524.11 CDJ49614.1 - 5.6 7.0 31.2 4.7 7.2 15.1 2.4 2 0 0 2 2 2 0 rRNA processing DUF2052 PF09747.9 CDJ49614.1 - 9.3 6.3 17.7 13 5.9 0.7 2.8 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) DUF4834 PF16118.5 CDJ49616.1 - 0.28 12.2 45.5 2.6 9.1 15.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF2232 PF09991.9 CDJ49616.1 - 4.4 6.4 13.6 6.5 5.9 0.6 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) SR-25 PF10500.9 CDJ49618.1 - 5.5 6.5 15.2 2.3 7.8 8.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ49618.1 - 6.6 7.5 12.7 16 6.3 5.1 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ49620.1 - 1.4e-05 24.8 8.0 1.4e-05 24.8 8.0 14.2 11 4 1 13 13 13 3 Nuclear RNA-splicing-associated protein DUF2232 PF09991.9 CDJ49621.1 - 6.6 5.8 6.0 1.7 7.7 1.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) RRM_1 PF00076.22 CDJ49622.1 - 0.056 13.3 0.0 15 5.5 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CDJ49622.1 - 0.084 12.9 0.3 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 RNA binding domain Spt20 PF12090.8 CDJ49622.1 - 5.7 6.5 15.5 9.2 5.8 15.5 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ49623.1 - 0.00072 19.7 4.0 0.00072 19.7 4.0 2.8 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ49623.1 - 0.00084 19.0 3.6 0.00084 19.0 3.6 3.5 2 1 0 2 2 2 1 Spt20 family DUF2722 PF10846.8 CDJ49623.1 - 0.001 18.1 1.3 0.001 18.1 1.3 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) SARAF PF06682.12 CDJ49623.1 - 0.016 14.9 15.2 0.033 13.8 5.1 2.7 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis eIF-3_zeta PF05091.12 CDJ49623.1 - 0.3 10.0 18.1 0.11 11.5 10.2 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.6 CDJ49623.1 - 0.42 8.9 5.3 0.83 8.0 5.3 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GNT-I PF03071.15 CDJ49623.1 - 0.6 8.8 12.1 1.1 7.9 12.1 1.4 1 0 0 1 1 1 0 GNT-I family TniQ PF06527.11 CDJ49623.1 - 4 8.1 9.5 0.55 10.9 0.3 2.8 2 0 0 2 2 2 0 TniQ Peptidase_S64 PF08192.11 CDJ49623.1 - 6.7 5.1 19.1 3 6.2 15.3 1.9 2 0 0 2 2 2 0 Peptidase family S64 AbLIM_anchor PF16182.5 CDJ49623.1 - 7.5 6.3 16.3 2.2 8.0 12.1 2.1 2 0 0 2 2 2 0 Putative adherens-junction anchoring region of AbLIM Spt20 PF12090.8 CDJ49626.1 - 0.00053 19.7 34.5 0.0006 19.5 34.5 1.3 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ49626.1 - 0.00098 18.2 26.4 0.0011 18.0 26.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF1644 PF07800.12 CDJ49626.1 - 0.066 13.3 7.7 0.074 13.1 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) SpoIIP PF07454.11 CDJ49626.1 - 0.068 12.6 13.4 0.072 12.5 13.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4770 PF15994.5 CDJ49626.1 - 0.11 12.7 11.3 0.1 12.8 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) BAF1_ABF1 PF04684.13 CDJ49626.1 - 0.15 11.1 19.3 0.16 11.0 19.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PPL5 PF18168.1 CDJ49626.1 - 0.19 11.0 9.0 0.23 10.8 9.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF2368 PF10166.9 CDJ49626.1 - 0.25 11.0 17.1 0.3 10.7 17.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) TERB2 PF15101.6 CDJ49626.1 - 0.26 11.3 18.0 0.27 11.3 18.0 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TFIIA PF03153.13 CDJ49626.1 - 0.29 11.1 40.9 0.34 10.9 40.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 CDJ49626.1 - 0.33 10.6 7.8 0.36 10.5 7.8 1.2 1 0 0 1 1 1 0 FAM176 family Suf PF05843.14 CDJ49626.1 - 0.39 10.6 16.0 0.38 10.7 16.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Auxin_canalis PF05703.11 CDJ49626.1 - 0.46 10.4 18.3 0.62 10.0 18.3 1.2 1 0 0 1 1 1 0 Auxin canalisation Connexin PF00029.19 CDJ49626.1 - 0.53 10.0 10.0 0.56 9.9 10.0 1.1 1 0 0 1 1 1 0 Connexin UPF0524 PF15823.5 CDJ49626.1 - 0.58 9.5 7.9 0.62 9.4 7.9 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 RLL PF10036.9 CDJ49626.1 - 0.64 9.8 19.5 0.73 9.6 19.5 1.1 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein EIF4E-T PF10477.9 CDJ49626.1 - 0.73 8.6 18.7 0.66 8.7 18.7 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Band_3_cyto PF07565.13 CDJ49626.1 - 0.79 9.5 11.5 0.79 9.5 11.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Tim54 PF11711.8 CDJ49626.1 - 0.85 8.3 11.8 0.84 8.4 11.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EPL1 PF10513.9 CDJ49626.1 - 0.86 10.0 15.4 1.2 9.6 15.4 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like EOS1 PF12326.8 CDJ49626.1 - 1 9.2 6.6 1 9.3 6.6 1.2 1 0 0 1 1 1 0 N-glycosylation protein DDHD PF02862.17 CDJ49626.1 - 1.1 9.4 13.5 1.2 9.2 13.5 1.2 1 0 0 1 1 1 0 DDHD domain ABC2_membrane_2 PF12679.7 CDJ49626.1 - 1.3 8.3 6.7 1.5 8.1 6.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein NPR3 PF03666.13 CDJ49626.1 - 1.3 7.7 11.8 1.2 7.9 11.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MMU163 PF17119.5 CDJ49626.1 - 1.4 8.0 5.9 1.4 8.0 5.9 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis PTPRCAP PF15713.5 CDJ49626.1 - 1.4 9.2 17.7 1.6 9.0 17.7 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Gti1_Pac2 PF09729.9 CDJ49626.1 - 1.5 8.9 11.5 1.5 8.9 11.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family F-protein PF00469.20 CDJ49626.1 - 1.5 8.4 10.8 1.6 8.3 10.8 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef MMR1 PF08505.10 CDJ49626.1 - 1.6 9.0 17.1 1.8 8.8 17.1 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein MecA PF05389.12 CDJ49626.1 - 1.7 8.3 12.4 2.1 7.9 12.4 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) CDC45 PF02724.14 CDJ49626.1 - 1.8 6.7 11.8 1.8 6.8 11.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3292 PF11696.8 CDJ49626.1 - 2.1 6.6 14.8 2.5 6.4 14.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) CLN3 PF02487.17 CDJ49626.1 - 2.1 7.3 10.0 2.1 7.3 10.0 1.1 1 0 0 1 1 1 0 CLN3 protein FAM91_C PF14648.6 CDJ49626.1 - 2.3 6.9 7.3 2.4 6.9 7.3 1.1 1 0 0 1 1 1 0 FAM91 C-terminus DUF3371 PF11851.8 CDJ49626.1 - 2.4 9.2 14.9 3.2 8.9 14.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Membralin PF09746.9 CDJ49626.1 - 2.5 7.0 6.7 2.3 7.1 6.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein Activator_LAG-3 PF11498.8 CDJ49626.1 - 2.6 6.9 44.6 2.5 7.0 44.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 eIF-3_zeta PF05091.12 CDJ49626.1 - 2.6 6.9 22.7 2.7 6.9 22.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF5308 PF17233.2 CDJ49626.1 - 2.7 8.2 17.7 3.7 7.8 17.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Otopetrin PF03189.13 CDJ49626.1 - 3.1 6.5 9.3 3.5 6.3 9.3 1.1 1 0 0 1 1 1 0 Otopetrin DUF4746 PF15928.5 CDJ49626.1 - 3.1 7.1 10.8 3.2 7.1 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MDM10 PF12519.8 CDJ49626.1 - 3.1 6.6 12.2 3.3 6.5 12.2 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Ctr PF04145.15 CDJ49626.1 - 3.2 8.4 9.2 3.2 8.4 9.2 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Pex14_N PF04695.13 CDJ49626.1 - 3.3 8.3 26.9 3.8 8.1 26.5 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pannexin_like PF12534.8 CDJ49626.1 - 3.4 6.7 9.8 3.3 6.7 9.8 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 MDM31_MDM32 PF08118.11 CDJ49626.1 - 3.4 6.2 8.3 3.3 6.3 8.3 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins OATP PF03137.20 CDJ49626.1 - 3.6 5.8 8.1 3.4 5.8 8.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF913 PF06025.12 CDJ49626.1 - 3.6 6.5 8.7 3.5 6.5 8.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Glyco_hydro_9 PF00759.19 CDJ49626.1 - 3.6 6.9 12.6 4.3 6.7 12.6 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Sec62 PF03839.16 CDJ49626.1 - 3.9 6.9 11.2 4.1 6.9 11.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4554 PF15091.6 CDJ49626.1 - 4.2 6.1 16.5 4.7 6.0 16.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) SID-1_RNA_chan PF13965.6 CDJ49626.1 - 4.4 5.6 6.5 4.4 5.6 6.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 CDJ49626.1 - 4.9 6.9 16.1 5.4 6.8 16.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BAT2_N PF07001.11 CDJ49626.1 - 5 7.5 23.4 6.4 7.2 23.4 1.2 1 0 0 1 1 1 0 BAT2 N-terminus NST1 PF13945.6 CDJ49626.1 - 5.2 7.1 25.2 5.7 7.0 25.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Cellulose_synt PF03552.14 CDJ49626.1 - 5.8 5.3 5.6 5.5 5.4 5.6 1.0 1 0 0 1 1 1 0 Cellulose synthase Dicty_REP PF05086.12 CDJ49626.1 - 6.2 4.7 8.0 6.1 4.7 8.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_memb PF02932.16 CDJ49626.1 - 6.3 6.8 14.9 7.4 6.6 14.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4638 PF15472.6 CDJ49626.1 - 6.5 6.4 14.8 6.3 6.5 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) ALMT PF11744.8 CDJ49626.1 - 6.5 5.5 11.9 6.4 5.5 11.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_S64 PF08192.11 CDJ49626.1 - 7 5.0 12.5 7.2 5.0 12.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Mem_trans PF03547.18 CDJ49626.1 - 7.1 4.9 6.1 6.8 5.0 6.1 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF2828 PF11443.8 CDJ49626.1 - 7.3 4.5 15.0 6.9 4.6 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) UPF0560 PF10577.9 CDJ49626.1 - 7.7 4.9 22.9 8.1 4.8 22.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 BT1 PF03092.16 CDJ49626.1 - 9.2 4.4 5.5 9.7 4.3 5.5 1.0 1 0 0 1 1 1 0 BT1 family Draxin PF15550.6 CDJ49627.1 - 0.026 14.4 16.9 0.032 14.1 16.9 1.2 1 0 0 1 1 1 0 Draxin BAF1_ABF1 PF04684.13 CDJ49627.1 - 0.18 10.8 17.6 0.22 10.6 17.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RR_TM4-6 PF06459.12 CDJ49627.1 - 0.22 11.3 18.2 0.28 11.0 18.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPAT_C PF15712.5 CDJ49627.1 - 0.23 10.1 24.5 0.29 9.7 24.5 1.0 1 0 0 1 1 1 0 NPAT C terminus CDC45 PF02724.14 CDJ49627.1 - 0.34 9.1 16.3 0.41 8.9 16.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SOBP PF15279.6 CDJ49627.1 - 0.47 11.0 14.9 0.57 10.7 14.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein LAP1C PF05609.12 CDJ49627.1 - 0.57 9.2 15.6 0.68 9.0 15.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) YihI PF04220.12 CDJ49627.1 - 0.79 9.4 22.3 0.49 10.1 20.6 1.5 1 1 0 1 1 1 0 Der GTPase activator (YihI) DUF4614 PF15391.6 CDJ49627.1 - 0.94 9.4 15.2 1.6 8.7 15.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Nop53 PF07767.11 CDJ49627.1 - 0.95 8.8 25.5 1.1 8.5 25.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SOG2 PF10428.9 CDJ49627.1 - 1.2 8.2 15.9 1.3 8.1 15.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Cellulose_synt PF03552.14 CDJ49627.1 - 1.6 7.2 7.3 1.9 6.9 7.3 1.0 1 0 0 1 1 1 0 Cellulose synthase Hamartin PF04388.12 CDJ49627.1 - 2.4 6.7 11.9 2.6 6.6 11.9 1.1 1 0 0 1 1 1 0 Hamartin protein PA26 PF04636.13 CDJ49627.1 - 3 6.6 9.2 3.3 6.5 9.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Dsh_C PF12316.8 CDJ49627.1 - 3.4 8.0 21.5 5.1 7.5 21.5 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF913 PF06025.12 CDJ49627.1 - 3.7 6.4 9.9 4.7 6.1 9.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ALMT PF11744.8 CDJ49627.1 - 5.2 5.8 10.9 6.1 5.6 10.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF5427 PF10310.9 CDJ49627.1 - 5.8 5.8 25.7 6.9 5.5 25.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DDRGK PF09756.9 CDJ49627.1 - 6.3 6.4 22.9 8.8 5.9 22.9 1.2 1 0 0 1 1 1 0 DDRGK domain SLC12 PF03522.15 CDJ49627.1 - 8.4 5.3 13.2 9.6 5.1 13.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RVT_1 PF00078.27 CDJ49629.1 - 2.1e-10 40.5 0.0 3.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CDJ49629.1 - 8.3e-08 32.1 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ49629.1 - 1.8e-07 31.7 0.0 4.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ49629.1 - 6.2e-07 29.9 0.0 3.7e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ49629.1 - 0.0088 16.3 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ49629.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Ribo_biogen_C PF04034.13 CDJ49632.1 - 1e-12 47.9 3.1 1.2e-12 47.6 1.7 1.8 1 1 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CDJ49632.1 - 0.00038 20.2 1.4 0.0007 19.4 0.0 2.0 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI RskA PF10099.9 CDJ49632.1 - 0.0039 17.5 11.2 0.0039 17.5 11.2 5.3 1 1 3 4 4 4 1 Anti-sigma-K factor rskA MID_MedPIWI PF18296.1 CDJ49632.1 - 0.036 13.9 12.6 0.18 11.6 4.1 2.5 2 0 0 2 2 2 0 MID domain of medPIWI CCG PF02754.16 CDJ49632.1 - 2.6 8.3 7.0 5.7 7.2 1.5 3.0 2 1 1 3 3 3 0 Cysteine-rich domain RSRP PF17069.5 CDJ49632.1 - 3.7 7.0 33.7 0.054 13.1 26.0 1.8 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 Coilin_N PF15862.5 CDJ49632.1 - 4.1 7.2 20.7 2.6 7.8 3.8 2.4 2 0 0 2 2 2 0 Coilin N-terminus DUF913 PF06025.12 CDJ49632.1 - 8.5 5.2 12.1 1.3 7.9 3.6 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Ribosomal_L44 PF00935.19 CDJ49633.1 - 1.2e-22 80.2 9.4 1.2e-22 80.2 9.4 2.4 2 0 0 2 2 2 1 Ribosomal protein L44 TFIIA PF03153.13 CDJ49633.1 - 0.0075 16.3 23.6 0.014 15.4 23.6 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ49633.1 - 0.016 14.8 22.0 0.42 10.2 13.3 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ49633.1 - 0.039 13.9 5.0 0.08 12.9 5.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex26 PF07163.12 CDJ49633.1 - 0.064 12.5 12.7 0.5 9.6 8.2 2.4 2 0 0 2 2 2 0 Pex26 protein Pannexin_like PF12534.8 CDJ49633.1 - 0.48 9.5 1.8 0.96 8.5 1.8 1.5 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Presenilin PF01080.17 CDJ49633.1 - 2.1 7.0 8.0 0.53 9.0 4.6 1.7 2 0 0 2 2 2 0 Presenilin CBP_BcsG PF11658.8 CDJ49633.1 - 3.3 6.0 7.4 2.8 6.2 3.7 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG Connexin PF00029.19 CDJ49633.1 - 4.7 6.9 4.7 0.55 10.0 0.5 1.6 2 0 0 2 2 2 0 Connexin DUF913 PF06025.12 CDJ49634.1 - 0.12 11.3 4.3 0.13 11.3 4.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hamartin PF04388.12 CDJ49634.1 - 0.13 10.9 13.5 0.15 10.7 13.5 1.0 1 0 0 1 1 1 0 Hamartin protein Hid1 PF12722.7 CDJ49634.1 - 0.26 9.4 9.8 0.27 9.3 9.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 CDJ49634.1 - 0.33 9.9 8.9 0.4 9.6 8.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Endostatin PF06482.11 CDJ49634.1 - 0.49 9.8 9.7 0.56 9.6 9.7 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin ERbeta_N PF12497.8 CDJ49634.1 - 0.51 10.1 2.9 0.97 9.2 2.9 1.4 1 0 0 1 1 1 0 Estrogen receptor beta DUF2828 PF11443.8 CDJ49634.1 - 0.84 7.7 6.7 0.98 7.4 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) V_ATPase_I PF01496.19 CDJ49634.1 - 1.1 7.1 15.4 1.4 6.8 15.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 CDJ49634.1 - 1.2 9.1 7.7 1.6 8.7 7.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDM31_MDM32 PF08118.11 CDJ49634.1 - 1.4 7.5 4.3 2 7.0 4.3 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins CSG2 PF16965.5 CDJ49634.1 - 2.1 7.2 3.9 2.6 6.9 3.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Neuregulin PF02158.15 CDJ49634.1 - 2.9 7.2 17.9 5.3 6.3 18.0 1.4 1 1 0 1 1 1 0 Neuregulin intracellular region Saw1 PF11561.8 CDJ49634.1 - 3 7.3 8.1 4.8 6.7 8.1 1.3 1 0 0 1 1 1 0 Single strand annealing-weakened 1 CLN3 PF02487.17 CDJ49634.1 - 4.9 6.1 9.5 7.4 5.5 9.4 1.3 1 1 0 1 1 1 0 CLN3 protein Sec62 PF03839.16 CDJ49634.1 - 8.3 5.8 8.8 14 5.1 7.1 1.8 2 0 0 2 2 2 0 Translocation protein Sec62 PTPRCAP PF15713.5 CDJ49634.1 - 9.6 6.5 20.2 25 5.2 20.1 1.7 1 1 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PAT1 PF09770.9 CDJ49634.1 - 9.9 4.3 34.1 12 4.1 34.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1664 PF07889.12 CDJ49636.1 - 0.063 13.3 2.5 0.17 11.9 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TFIIA PF03153.13 CDJ49636.1 - 0.48 10.4 30.3 0.16 11.9 19.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ49636.1 - 3.5 5.4 9.2 7.2 4.4 0.3 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Lin-8 PF03353.15 CDJ49637.1 - 3.2 7.2 27.9 1.8 8.1 13.8 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist RskA PF10099.9 CDJ49637.1 - 3.7 7.8 29.3 1.8e+04 -9.3 29.3 3.2 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SLC12 PF03522.15 CDJ49637.1 - 9 5.2 18.6 4.7 6.1 0.6 2.1 2 0 0 2 2 2 0 Solute carrier family 12 DDHD PF02862.17 CDJ49638.1 - 0.02 15.1 5.7 2.8 8.1 0.1 2.6 2 0 0 2 2 2 0 DDHD domain TFIIA PF03153.13 CDJ49638.1 - 0.031 14.3 62.5 0.026 14.5 23.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ49638.1 - 1.5 8.6 20.6 0.23 11.3 0.5 2.3 2 0 0 2 2 2 0 SPX domain V_ATPase_I PF01496.19 CDJ49638.1 - 6 4.7 17.7 0.83 7.5 7.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 CDJ49638.1 - 6.4 7.2 34.4 0.042 14.4 11.0 3.2 4 0 0 4 4 4 0 AAA domain Allexi_40kDa PF05549.11 CDJ49638.1 - 8.1 5.9 8.5 2.3 7.6 2.3 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Ank_2 PF12796.7 CDJ49639.1 - 4e-16 59.4 0.8 1.8e-05 25.2 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ49639.1 - 2.8e-14 53.3 5.1 0.0041 17.7 0.1 4.7 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ49639.1 - 9.6e-14 51.3 1.1 0.0015 18.8 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ49639.1 - 7e-09 35.2 2.9 0.027 15.0 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 CDJ49639.1 - 1.1e-08 35.2 6.3 0.0034 17.8 0.1 5.8 6 0 0 6 6 6 2 Ankyrin repeat MPC PF03650.13 CDJ49641.1 - 1.3e-08 34.9 1.1 2.4e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial pyruvate carriers Spt20 PF12090.8 CDJ49641.1 - 0.12 12.0 8.2 0.13 11.9 8.2 1.0 1 0 0 1 1 1 0 Spt20 family DUF2116 PF09889.9 CDJ49641.1 - 0.53 10.3 2.8 0.74 9.8 2.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) NESP55 PF06390.12 CDJ49642.1 - 5 6.6 42.4 2.5 7.6 12.7 3.1 1 1 2 3 3 3 0 Neuroendocrine-specific golgi protein P55 (NESP55) Sec62 PF03839.16 CDJ49642.1 - 9.6 5.6 6.3 16 4.9 6.3 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 LEA_2 PF03168.13 CDJ49643.1 - 0.12 12.9 0.0 1.7 9.2 0.0 2.0 2 0 0 2 2 2 0 Late embryogenesis abundant protein DUF728 PF05304.12 CDJ49643.1 - 1.6 8.6 5.5 9.2 6.1 0.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF728) Sporozoite_P67 PF05642.11 CDJ49644.1 - 0.0027 15.9 0.1 0.0027 15.9 0.1 4.4 3 2 0 3 3 3 1 Sporozoite P67 surface antigen BatA PF07584.11 CDJ49644.1 - 5.8 7.3 9.5 1.3 9.5 0.1 4.7 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal PBP1_TM PF14812.6 CDJ49645.1 - 0.79 10.1 6.9 1.5 9.2 6.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Utp14 PF04615.13 CDJ49645.1 - 1.2 7.7 13.2 1.5 7.3 13.2 1.3 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.10 CDJ49645.1 - 2.7 7.2 19.7 4.4 6.5 19.7 1.3 1 0 0 1 1 1 0 BUD22 GREB1 PF15782.5 CDJ49645.1 - 3 4.8 5.1 3.4 4.7 5.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SDA1 PF05285.12 CDJ49645.1 - 3.6 6.9 13.6 4.9 6.5 13.6 1.2 1 0 0 1 1 1 0 SDA1 RskA PF10099.9 CDJ49646.1 - 0.00071 19.9 3.3 0.0014 18.9 3.3 1.5 1 1 0 1 1 1 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ49646.1 - 0.029 14.4 12.5 0.029 14.4 12.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pet20 PF08692.10 CDJ49646.1 - 0.083 13.6 0.6 0.11 13.2 0.6 1.1 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Glyoxalase_3 PF13468.6 CDJ49646.1 - 0.19 11.9 4.4 0.23 11.6 4.4 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Neur_chan_memb PF02932.16 CDJ49646.1 - 0.66 10.0 1.5 0.71 9.9 1.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2098 PF09871.9 CDJ49646.1 - 1.1 9.7 3.7 1.5 9.2 3.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Presenilin PF01080.17 CDJ49646.1 - 1.2 7.8 3.4 1.3 7.7 3.4 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ49646.1 - 2.6 7.6 19.3 3.3 7.3 19.3 1.2 1 0 0 1 1 1 0 Spt20 family Cupin_8 PF13621.6 CDJ49647.1 - 4.1e-26 92.2 0.0 8.4e-25 87.9 0.0 2.3 2 1 0 2 2 2 1 Cupin-like domain DUF2722 PF10846.8 CDJ49647.1 - 7.1e-05 21.9 7.1 7.1e-05 21.9 7.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) SseC PF04888.12 CDJ49647.1 - 0.0095 15.6 0.6 0.0095 15.6 0.6 3.5 3 1 0 3 3 2 1 Secretion system effector C (SseC) like family MPM1 PF17234.2 CDJ49647.1 - 0.36 11.1 23.9 3.4 7.9 5.1 2.7 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Gram_pos_anchor PF00746.21 CDJ49647.1 - 0.46 10.5 4.1 2.1 8.4 0.2 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Ribosomal_60s PF00428.19 CDJ49647.1 - 1.3 9.7 29.2 2.1 9.0 15.8 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Exonuc_VII_L PF02601.15 CDJ49647.1 - 1.5 8.3 29.2 0.77 9.3 0.2 3.0 3 0 0 3 3 3 0 Exonuclease VII, large subunit IER PF05760.12 CDJ49647.1 - 2 8.6 29.6 5.1 7.3 0.7 3.1 3 0 0 3 3 3 0 Immediate early response protein (IER) Med15 PF09606.10 CDJ49647.1 - 2.1 7.0 57.9 0.38 9.4 16.2 3.1 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.6 CDJ49647.1 - 2.3 8.7 26.9 7 7.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain Miga PF10265.9 CDJ49647.1 - 3.2 6.6 25.9 0.085 11.8 0.2 2.9 3 0 0 3 3 3 0 Mitoguardin TERB2 PF15101.6 CDJ49647.1 - 4 7.5 36.4 0.026 14.6 2.2 3.2 4 0 0 4 4 3 0 Telomere-associated protein TERB2 Pap_E4 PF02711.14 CDJ49647.1 - 4.4 8.3 19.1 8 7.5 9.0 2.7 2 0 0 2 2 2 0 E4 protein Pex19 PF04614.12 CDJ49647.1 - 5 6.8 31.8 0.025 14.3 3.7 3.3 3 0 0 3 3 3 0 Pex19 protein family DUF3138 PF11336.8 CDJ49647.1 - 5.3 5.5 30.3 0.13 10.8 12.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) SRP-alpha_N PF04086.13 CDJ49647.1 - 9.9 6.0 30.5 3.7 7.4 11.6 3.7 4 0 0 4 4 4 0 Signal recognition particle, alpha subunit, N-terminal RskA PF10099.9 CDJ49648.1 - 0.0003 21.2 47.3 0.00043 20.6 2.1 3.9 2 1 1 3 3 3 2 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ49648.1 - 1.3 10.0 7.0 4.2 8.4 1.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Chromo PF00385.24 CDJ49651.1 - 2.3e-11 43.4 0.0 4.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CDJ49651.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 CDJ49652.1 - 2.8e-21 76.0 0.0 4.8e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ49652.1 - 3.2e-14 53.1 0.6 7e-14 52.0 0.2 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ49652.1 - 5e-06 26.5 0.1 1.9e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 CDJ49653.1 - 5.6e-10 39.7 0.0 1.1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ49653.1 - 4.7e-09 36.7 0.0 9.9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ49653.1 - 5.6e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CDJ49653.1 - 0.002 18.4 0.2 0.011 16.1 0.0 2.3 3 0 0 3 3 3 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 CDJ49653.1 - 0.039 14.2 0.0 0.039 14.2 0.0 3.4 3 1 1 4 4 4 0 Retrotransposon gag protein TFIIA PF03153.13 CDJ49654.1 - 0.13 12.3 17.2 0.16 11.9 17.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ49655.1 - 0.0034 17.7 13.7 0.0034 17.7 13.7 24.1 8 7 11 20 20 20 9 Anti-sigma-K factor rskA uDENN PF03456.18 CDJ49655.1 - 0.059 14.1 0.6 2.5 8.9 0.4 3.7 2 0 0 2 2 2 0 uDENN domain AF-4 PF05110.13 CDJ49656.1 - 0.00071 17.8 36.1 0.00087 17.5 36.1 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein RAP1 PF07218.11 CDJ49656.1 - 0.019 13.3 1.8 0.021 13.1 1.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HI0933_like PF03486.14 CDJ49656.1 - 0.033 12.9 14.0 0.043 12.5 14.0 1.3 1 0 0 1 1 1 0 HI0933-like protein CCSAP PF15748.5 CDJ49656.1 - 0.034 14.3 27.4 0.044 13.9 27.4 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF5427 PF10310.9 CDJ49656.1 - 0.044 12.8 28.9 0.054 12.5 28.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Nrap_D3 PF17404.2 CDJ49656.1 - 0.064 13.3 9.0 0.087 12.9 9.0 1.3 1 0 0 1 1 1 0 Nrap protein domain 3 TFIIA PF03153.13 CDJ49656.1 - 0.1 12.6 57.6 0.18 11.8 57.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ49656.1 - 0.12 10.7 39.7 0.13 10.5 39.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ49656.1 - 0.24 11.0 35.3 0.72 9.4 21.4 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ49656.1 - 0.25 11.3 27.1 0.33 10.9 27.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4698 PF15769.5 CDJ49656.1 - 0.29 10.2 27.0 0.34 9.9 27.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) DUF4746 PF15928.5 CDJ49656.1 - 0.36 10.2 9.8 0.44 9.9 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Caldesmon PF02029.15 CDJ49656.1 - 0.57 8.9 20.8 0.65 8.7 20.8 1.1 1 0 0 1 1 1 0 Caldesmon Asp-B-Hydro_N PF05279.11 CDJ49656.1 - 0.57 10.2 8.5 0.62 10.1 8.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Exonuc_VII_L PF02601.15 CDJ49656.1 - 0.58 9.7 26.8 0.73 9.3 26.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Draxin PF15550.6 CDJ49656.1 - 0.82 9.5 15.6 0.97 9.2 15.6 1.0 1 0 0 1 1 1 0 Draxin FTO_NTD PF12933.7 CDJ49656.1 - 1.2 8.3 12.4 1.6 7.9 12.4 1.4 1 0 0 1 1 1 0 FTO catalytic domain SKA1 PF07160.12 CDJ49656.1 - 1.3 8.8 23.7 1.6 8.5 23.7 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF4175 PF13779.6 CDJ49656.1 - 1.4 6.7 53.3 1.7 6.5 53.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SOBP PF15279.6 CDJ49656.1 - 1.7 9.2 27.8 2.2 8.8 27.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein FapA PF03961.13 CDJ49656.1 - 1.7 7.1 13.8 2.1 6.9 13.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A PdaC PF13739.6 CDJ49656.1 - 2.2 9.3 6.5 4.1 8.4 6.5 1.5 1 1 0 1 1 1 0 Deacetylase PdaC DUF572 PF04502.13 CDJ49656.1 - 2.4 7.7 21.5 3.3 7.3 21.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) eIF-3_zeta PF05091.12 CDJ49656.1 - 2.6 6.9 23.8 3.8 6.4 23.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ49656.1 - 3.3 5.5 19.8 3.7 5.4 19.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 CDJ49656.1 - 3.7 7.3 19.4 4.9 6.9 19.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PA26 PF04636.13 CDJ49656.1 - 3.8 6.3 16.0 5 5.9 16.0 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CENP-O PF09496.10 CDJ49656.1 - 4.9 7.1 17.7 6.5 6.7 17.7 1.2 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component PIN_12 PF16289.5 CDJ49656.1 - 6 7.3 9.2 8.1 6.9 9.2 1.2 1 0 0 1 1 1 0 PIN domain Tam41_Mmp37 PF09139.11 CDJ49656.1 - 7.4 5.9 21.2 9.5 5.5 21.2 1.1 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial SLC12 PF03522.15 CDJ49656.1 - 7.8 5.4 22.9 9 5.2 22.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Virul_Fac PF10139.9 CDJ49656.1 - 8.1 4.5 21.7 9.7 4.3 21.7 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor YqfD PF06898.11 CDJ49656.1 - 8.3 5.1 8.4 3.7 6.3 6.4 1.3 1 1 0 1 1 1 0 Putative stage IV sporulation protein YqfD Spt20 PF12090.8 CDJ49657.1 - 0.00048 19.8 9.6 0.00048 19.8 9.6 2.0 2 0 0 2 2 2 1 Spt20 family LIM_bind PF01803.16 CDJ49657.1 - 0.2 11.2 3.0 0.4 10.2 3.0 1.6 1 0 0 1 1 1 0 LIM-domain binding protein Suf PF05843.14 CDJ49657.1 - 0.59 10.1 9.5 1.9 8.4 4.8 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.8 CDJ49657.1 - 0.65 8.9 19.3 1.5 7.7 19.3 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Roughex PF06020.11 CDJ49657.1 - 8.5 5.4 9.4 20 4.2 9.4 1.6 1 0 0 1 1 1 0 Drosophila roughex protein RskA PF10099.9 CDJ49658.1 - 0.0031 17.8 14.4 0.0031 17.8 14.4 11.2 2 1 4 6 6 6 2 Anti-sigma-K factor rskA NifU_N PF01592.16 CDJ49659.1 - 3.6e-35 120.9 0.1 4.3e-35 120.6 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain UBA PF00627.31 CDJ49660.1 - 0.00063 19.6 0.7 0.0026 17.6 0.7 2.1 1 1 0 1 1 1 1 UBA/TS-N domain DUF4410 PF14366.6 CDJ49660.1 - 0.0058 16.5 0.9 0.017 15.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4410) DUF1319 PF07028.11 CDJ49660.1 - 0.1 12.8 0.2 0.15 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Metallophos PF00149.28 CDJ49661.1 - 4.3e-06 27.4 0.1 0.00028 21.4 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ49661.1 - 0.0078 16.4 0.1 0.4 10.9 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain IATP PF04568.12 CDJ49661.1 - 0.16 12.4 0.2 0.61 10.5 0.2 1.9 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP RILP PF11461.8 CDJ49663.1 - 3.6e-06 27.1 30.3 0.022 15.0 0.0 9.6 8 1 1 9 9 9 5 Rab interacting lysosomal protein DMAP1 PF05499.12 CDJ49663.1 - 0.1 12.5 0.0 0.1 12.5 0.0 8.3 8 1 0 8 8 8 0 DNA methyltransferase 1-associated protein 1 (DMAP1) McrBC PF10117.9 CDJ49663.1 - 0.89 8.6 4.8 0.93 8.6 0.7 2.8 3 0 0 3 3 3 0 McrBC 5-methylcytosine restriction system component PPR_2 PF13041.6 CDJ49664.1 - 1.6e-46 156.3 2.9 3e-15 56.1 0.0 7.1 1 1 6 7 7 7 6 PPR repeat family PPR_1 PF12854.7 CDJ49664.1 - 1.5e-33 114.2 2.7 1.9e-08 33.9 0.0 7.2 7 0 0 7 7 7 6 PPR repeat PPR_3 PF13812.6 CDJ49664.1 - 7.5e-33 112.4 0.0 6.5e-14 51.8 0.0 4.2 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 CDJ49664.1 - 9.8e-32 107.0 9.2 5.2e-06 26.4 0.0 8.4 8 1 0 8 8 8 4 PPR repeat PPR_long PF17177.4 CDJ49664.1 - 2.2e-17 63.2 0.0 1.4e-12 47.4 0.0 2.9 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 CDJ49664.1 - 0.00047 20.0 0.0 4.2 7.3 0.0 3.2 3 0 0 3 3 3 1 Mitochondrial ATPase expression TruB_C PF09142.11 CDJ49664.1 - 0.11 12.3 0.2 0.33 10.7 0.2 1.8 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Actin PF00022.19 CDJ49666.1 - 3.9e-37 127.8 0.0 2.2e-22 79.3 0.0 2.9 2 1 0 2 2 2 2 Actin Coilin_N PF15862.5 CDJ49667.1 - 0.017 14.9 4.8 0.018 14.8 4.8 1.2 1 0 0 1 1 1 0 Coilin N-terminus zf-RING_2 PF13639.6 CDJ49667.1 - 0.033 14.5 0.6 0.052 13.9 0.6 1.3 1 0 0 1 1 1 0 Ring finger domain DUF4820 PF16091.5 CDJ49667.1 - 0.034 13.5 4.7 0.039 13.3 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Sec16 PF12932.7 CDJ49667.1 - 0.039 14.5 1.8 0.04 14.5 1.8 1.1 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region CTU2 PF10288.9 CDJ49667.1 - 0.08 13.2 7.9 0.089 13.0 7.9 1.1 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF4834 PF16118.5 CDJ49667.1 - 0.083 13.9 4.0 0.095 13.7 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) zf-rbx1 PF12678.7 CDJ49667.1 - 0.11 12.9 1.8 0.11 12.9 1.8 2.0 2 1 0 2 2 2 0 RING-H2 zinc finger domain FYDLN_acid PF09538.10 CDJ49667.1 - 0.22 12.2 6.9 0.34 11.6 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Presenilin PF01080.17 CDJ49667.1 - 0.65 8.7 5.8 0.63 8.8 5.8 1.0 1 0 0 1 1 1 0 Presenilin MRPL52 PF18699.1 CDJ49667.1 - 0.89 9.8 16.3 1.2 9.4 16.3 1.2 1 0 0 1 1 1 0 Mitoribosomal protein mL52 TFIIA PF03153.13 CDJ49667.1 - 2.5 8.0 25.0 2.6 7.9 25.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CDJ49668.1 - 0.0053 16.1 19.7 0.0072 15.7 19.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Ureide_permease PF07168.11 CDJ49668.1 - 0.016 14.0 1.8 0.017 13.9 1.8 1.0 1 0 0 1 1 1 0 Ureide permease Presenilin PF01080.17 CDJ49668.1 - 0.023 13.5 12.4 0.027 13.2 12.4 1.1 1 0 0 1 1 1 0 Presenilin Exonuc_VII_L PF02601.15 CDJ49668.1 - 0.023 14.3 29.4 0.027 14.0 29.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit T2SSF PF00482.23 CDJ49668.1 - 0.024 14.6 8.2 0.042 13.8 8.2 1.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F RR_TM4-6 PF06459.12 CDJ49668.1 - 0.037 13.8 9.5 0.041 13.7 9.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LAP1C PF05609.12 CDJ49668.1 - 0.047 12.8 16.7 0.056 12.5 16.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) HCO3_cotransp PF00955.21 CDJ49668.1 - 0.11 11.3 4.8 0.12 11.2 4.8 1.0 1 0 0 1 1 1 0 HCO3- transporter family VIT1 PF01988.19 CDJ49668.1 - 0.14 12.0 8.5 0.16 11.8 8.5 1.0 1 0 0 1 1 1 0 VIT family CSG2 PF16965.5 CDJ49668.1 - 0.14 11.0 5.7 0.18 10.7 5.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Scs3p PF10261.9 CDJ49668.1 - 0.16 11.5 3.4 0.2 11.1 3.4 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Connexin PF00029.19 CDJ49668.1 - 0.16 11.7 7.3 0.2 11.4 7.3 1.1 1 0 0 1 1 1 0 Connexin DUF2370 PF10176.9 CDJ49668.1 - 0.17 11.5 2.0 0.19 11.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) EOS1 PF12326.8 CDJ49668.1 - 0.18 11.7 3.3 0.25 11.2 3.3 1.3 1 0 0 1 1 1 0 N-glycosylation protein Sec62 PF03839.16 CDJ49668.1 - 0.19 11.2 9.9 0.24 10.9 9.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 ALMT PF11744.8 CDJ49668.1 - 0.27 10.0 9.0 0.31 9.8 9.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CLN3 PF02487.17 CDJ49668.1 - 0.28 10.2 10.2 0.31 10.0 10.2 1.1 1 0 0 1 1 1 0 CLN3 protein Sec20 PF03908.13 CDJ49668.1 - 0.37 10.8 15.2 0.52 10.3 15.2 1.3 1 0 0 1 1 1 0 Sec20 DDHD PF02862.17 CDJ49668.1 - 0.37 10.9 9.2 0.43 10.7 9.2 1.1 1 0 0 1 1 1 0 DDHD domain DUF4337 PF14235.6 CDJ49668.1 - 0.4 10.8 17.1 0.47 10.6 17.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FAM60A PF15396.6 CDJ49668.1 - 0.51 10.3 8.8 0.6 10.1 8.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SID-1_RNA_chan PF13965.6 CDJ49668.1 - 0.61 8.4 4.1 0.75 8.1 4.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ABC2_membrane_3 PF12698.7 CDJ49668.1 - 0.66 9.0 5.3 0.88 8.6 5.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein V_ATPase_I PF01496.19 CDJ49668.1 - 0.69 7.8 17.2 0.79 7.6 17.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FliP PF00813.20 CDJ49668.1 - 0.76 9.6 6.8 1 9.2 6.8 1.1 1 0 0 1 1 1 0 FliP family TMPIT PF07851.13 CDJ49668.1 - 0.9 8.7 20.5 1.1 8.4 20.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein Serinc PF03348.15 CDJ49668.1 - 1.2 8.0 4.0 1.4 7.8 4.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) LMBR1 PF04791.16 CDJ49668.1 - 1.3 7.9 12.4 1.5 7.6 12.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein CemA PF03040.14 CDJ49668.1 - 1.4 8.8 10.8 1.9 8.3 10.8 1.2 1 0 0 1 1 1 0 CemA family Prominin PF05478.11 CDJ49668.1 - 1.5 6.6 16.3 1.8 6.4 16.3 1.2 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 CDJ49668.1 - 1.7 7.4 30.8 2.3 7.0 30.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DDRGK PF09756.9 CDJ49668.1 - 1.8 8.1 28.3 2.1 7.9 28.3 1.0 1 0 0 1 1 1 0 DDRGK domain ApoO PF09769.9 CDJ49668.1 - 2.2 8.2 13.7 2.8 7.9 13.7 1.2 1 0 0 1 1 1 0 Apolipoprotein O MMPL PF03176.15 CDJ49668.1 - 3.2 6.6 7.4 3.6 6.4 7.4 1.2 1 0 0 1 1 1 0 MMPL family Vma12 PF11712.8 CDJ49668.1 - 3.6 7.6 13.7 7.2 6.7 13.7 1.5 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase YabA PF06156.13 CDJ49668.1 - 4.2 8.1 21.9 6.9 7.4 21.9 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Ctr PF04145.15 CDJ49668.1 - 5.3 7.7 12.4 6.2 7.4 12.4 1.2 1 0 0 1 1 1 0 Ctr copper transporter family HSP70 PF00012.20 CDJ49668.1 - 6.2 4.9 14.3 7.3 4.6 14.3 1.0 1 0 0 1 1 1 0 Hsp70 protein Pox_G5 PF04599.12 CDJ49668.1 - 8.1 5.3 12.9 9.9 5.0 12.9 1.0 1 0 0 1 1 1 0 Poxvirus G5 protein DUF4192 PF13830.6 CDJ49668.1 - 9.2 6.2 9.4 10 6.0 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Noggin PF05806.12 CDJ49668.1 - 9.3 6.1 12.7 12 5.8 12.7 1.1 1 0 0 1 1 1 0 Noggin DUF3492 PF11997.8 CDJ49668.1 - 9.4 5.9 11.0 11 5.6 11.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) FUSC PF04632.12 CDJ49668.1 - 9.5 4.6 20.8 9.8 4.6 20.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2347 PF09804.9 CDJ49668.1 - 9.7 5.7 10.7 11 5.5 10.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) SR-25 PF10500.9 CDJ49669.1 - 0.00017 21.3 25.3 0.00021 21.0 25.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ49669.1 - 1.9 8.6 27.8 2.1 8.4 27.8 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TCP PF03634.13 CDJ49669.1 - 3.3 8.3 25.8 3.6 8.1 25.8 1.0 1 0 0 1 1 1 0 TCP family transcription factor PCSK9_C1 PF18459.1 CDJ49669.1 - 3.4 7.9 9.5 4.8 7.4 9.2 1.7 1 1 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain G0-G1_switch_2 PF15103.6 CDJ49669.1 - 3.9 7.9 13.4 4.4 7.8 13.4 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 Pex14_N PF04695.13 CDJ49669.1 - 6 7.5 27.0 7.2 7.2 27.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4407 PF14362.6 CDJ49669.1 - 6.9 5.9 22.1 7.3 5.8 22.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4820 PF16091.5 CDJ49669.1 - 7.6 5.8 15.7 9.4 5.5 15.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NARP1 PF12569.8 CDJ49669.1 - 9.5 5.0 21.9 9.1 5.0 21.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 LAP1C PF05609.12 CDJ49670.1 - 1.3 8.1 59.3 1.4 7.9 59.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 CDJ49670.1 - 5.8 3.9 53.3 8 3.4 53.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Aconitase PF00330.20 CDJ49671.1 - 1.2e-82 278.4 0.0 1.4e-82 278.2 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF1645 PF07816.11 CDJ49671.1 - 0.01 16.4 1.1 0.01 16.4 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Surp PF01805.20 CDJ49671.1 - 0.048 13.7 0.3 0.1 12.6 0.3 1.5 1 0 0 1 1 1 0 Surp module DUF3446 PF11928.8 CDJ49671.1 - 0.72 10.2 20.8 0.28 11.5 11.8 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Secretin_N_2 PF07655.13 CDJ49671.1 - 0.96 10.0 21.1 1.2 9.7 14.4 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain RAP1 PF07218.11 CDJ49671.1 - 1 7.5 6.2 1.7 6.9 6.2 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SUZ PF12752.7 CDJ49671.1 - 3.3 8.5 5.5 2.7 8.8 1.2 2.2 2 0 0 2 2 2 0 SUZ domain Rtf2 PF04641.12 CDJ49672.1 - 3.3e-45 154.5 7.0 8.1e-45 153.2 7.0 1.7 1 1 0 1 1 1 1 Rtf2 RING-finger PRTP PF01366.18 CDJ49672.1 - 0.59 8.1 3.7 1.4 6.9 3.6 1.6 1 1 0 1 1 1 0 Herpesvirus processing and transport protein AF-4 PF05110.13 CDJ49672.1 - 0.83 7.7 26.4 1.3 7.0 26.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Tub_N PF16322.5 CDJ49672.1 - 1.6 9.1 16.3 0.36 11.2 1.8 2.3 2 0 0 2 2 2 0 Tubby N-terminal Cofilin_ADF PF00241.20 CDJ49673.1 - 3.1e-27 94.8 0.0 4e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CAP PF00188.26 CDJ49674.1 - 0.0012 19.6 0.0 0.0017 19.2 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TSP_C PF05735.12 CDJ49674.1 - 0.12 12.3 0.0 1.6 8.6 0.0 2.0 2 0 0 2 2 2 0 Thrombospondin C-terminal region VCBS PF13517.6 CDJ49676.1 - 1e-08 35.6 0.0 0.036 14.7 0.0 3.6 3 1 1 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CDJ49676.1 - 1.1e-05 25.4 0.3 0.42 10.8 0.0 3.2 3 0 0 3 3 3 2 FG-GAP repeat DUF2722 PF10846.8 CDJ49676.1 - 0.00044 19.3 4.4 0.00044 19.3 4.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Roughex PF06020.11 CDJ49676.1 - 0.002 17.3 2.7 0.0026 16.9 2.7 1.2 1 0 0 1 1 1 1 Drosophila roughex protein TFIIA PF03153.13 CDJ49676.1 - 0.0021 18.1 10.0 0.0025 17.9 10.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TCP PF03634.13 CDJ49676.1 - 0.003 18.1 2.3 0.0044 17.6 2.3 1.2 1 0 0 1 1 1 1 TCP family transcription factor Itfg2 PF15907.5 CDJ49676.1 - 0.0043 16.2 1.2 0.068 12.2 1.1 2.0 1 1 0 2 2 2 1 Integrin-alpha FG-GAP repeat-containing protein 2 TcdB_toxin_midN PF12256.8 CDJ49676.1 - 0.0062 15.9 0.3 0.96 8.8 0.1 2.5 1 1 0 2 2 2 1 Insecticide toxin TcdB middle/N-terminal region MID_MedPIWI PF18296.1 CDJ49676.1 - 0.0084 15.9 2.6 0.011 15.5 2.6 1.1 1 0 0 1 1 1 1 MID domain of medPIWI Suf PF05843.14 CDJ49676.1 - 0.22 11.5 4.8 0.31 11.0 4.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM199X PF15814.5 CDJ49676.1 - 0.23 10.5 5.6 0.34 9.9 5.6 1.2 1 0 0 1 1 1 0 Protein family FAM199X CDK2AP PF09806.9 CDJ49676.1 - 0.3 11.1 8.3 0.49 10.4 8.3 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF5327 PF17261.2 CDJ49676.1 - 0.47 11.2 9.5 0.12 13.1 4.3 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Presenilin PF01080.17 CDJ49676.1 - 0.63 8.7 4.3 0.84 8.3 4.3 1.1 1 0 0 1 1 1 0 Presenilin ANAPC_CDC26 PF10471.9 CDJ49676.1 - 3.5 8.5 22.2 0.3 12.0 13.2 2.4 3 0 0 3 3 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4834 PF16118.5 CDJ49676.1 - 7.1 7.7 8.5 1.1 10.3 3.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Myc_N PF01056.18 CDJ49677.1 - 0.011 15.7 11.9 0.011 15.6 11.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF908 PF06012.12 CDJ49677.1 - 0.076 12.4 12.3 0.086 12.2 12.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) GEMIN8 PF15348.6 CDJ49677.1 - 0.14 12.4 16.5 0.18 12.1 16.5 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 TFIIA PF03153.13 CDJ49677.1 - 0.17 11.9 25.4 0.18 11.7 25.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3295 PF11702.8 CDJ49677.1 - 0.19 11.1 15.1 0.2 10.9 15.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) ESM4 PF15952.5 CDJ49677.1 - 0.86 10.0 16.7 1.1 9.6 16.7 1.3 1 0 0 1 1 1 0 Enhancer of split M4 family FGF-BP1 PF06473.12 CDJ49677.1 - 0.88 9.4 14.7 1.1 9.0 14.7 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF4050 PF13259.6 CDJ49677.1 - 0.93 9.8 13.8 1 9.6 13.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) LD_cluster2 PF18163.1 CDJ49677.1 - 1.6 8.2 5.8 2 7.9 5.8 1.1 1 0 0 1 1 1 0 SLOG cluster2 DUF4551 PF15087.6 CDJ49677.1 - 2 7.2 11.1 2 7.2 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) WDCP PF15390.6 CDJ49677.1 - 3.2 6.0 12.8 3.5 5.9 12.8 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Sec3_C PF09763.9 CDJ49677.1 - 3.5 5.9 13.3 3.7 5.8 13.3 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF3801 PF12687.7 CDJ49677.1 - 3.7 7.6 15.6 4.2 7.4 15.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) PepSY_TM PF03929.16 CDJ49677.1 - 4.1 7.0 4.2 4.2 7.0 4.2 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Presenilin PF01080.17 CDJ49677.1 - 4.9 5.8 16.8 4.6 5.9 16.8 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ49677.1 - 4.9 4.9 14.9 5.3 4.8 14.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4746 PF15928.5 CDJ49677.1 - 5 6.4 20.9 4.2 6.7 20.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) Zip PF02535.22 CDJ49677.1 - 5.5 6.1 9.2 5.4 6.1 9.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Sporozoite_P67 PF05642.11 CDJ49677.1 - 5.9 4.8 8.9 6.7 4.7 8.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM60A PF15396.6 CDJ49678.1 - 0.0066 16.5 24.6 0.0078 16.2 24.6 1.1 1 0 0 1 1 1 1 Protein Family FAM60A Presenilin PF01080.17 CDJ49678.1 - 0.027 13.3 42.2 0.033 13.0 42.2 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ49678.1 - 0.044 13.6 32.9 0.063 13.1 32.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ49678.1 - 0.044 12.1 26.3 0.049 11.9 26.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ49678.1 - 0.045 12.8 34.4 0.051 12.6 34.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 GAGA_bind PF06217.12 CDJ49678.1 - 0.072 13.4 28.3 0.082 13.2 28.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family AIF_C PF14721.6 CDJ49678.1 - 0.16 12.3 34.6 1.8e+04 -5.9 34.6 2.1 1 1 0 1 1 0 0 Apoptosis-inducing factor, mitochondrion-associated, C-term O-antigen_lig PF13425.6 CDJ49678.1 - 0.16 10.7 15.8 0.2 10.4 15.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4045 PF13254.6 CDJ49678.1 - 0.16 11.6 31.5 0.18 11.4 31.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Lin-8 PF03353.15 CDJ49678.1 - 0.46 10.0 37.7 0.61 9.6 37.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist V_ATPase_I PF01496.19 CDJ49678.1 - 0.53 8.1 31.5 0.76 7.6 31.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF572 PF04502.13 CDJ49678.1 - 0.55 9.8 31.2 0.64 9.6 31.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) LAP1C PF05609.12 CDJ49678.1 - 1 8.4 36.7 1.2 8.2 36.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SAGA-Tad1 PF12767.7 CDJ49678.1 - 1 9.0 30.2 1.2 8.8 30.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit ALMT PF11744.8 CDJ49678.1 - 1.5 7.6 26.5 1.7 7.4 26.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RIFIN PF02009.16 CDJ49678.1 - 1.5 8.6 28.2 1.8 8.3 28.2 1.1 1 0 0 1 1 1 0 Rifin DUF1387 PF07139.11 CDJ49678.1 - 1.6 8.4 33.6 2.1 8.0 33.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Smg8_Smg9 PF10220.9 CDJ49678.1 - 1.9 6.7 31.8 2.2 6.5 31.8 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Draxin PF15550.6 CDJ49678.1 - 2.4 8.0 25.3 2.6 7.8 25.3 1.0 1 0 0 1 1 1 0 Draxin Macoilin PF09726.9 CDJ49678.1 - 2.4 6.6 27.2 3.3 6.1 27.2 1.2 1 0 0 1 1 1 0 Macoilin family Raftlin PF15250.6 CDJ49678.1 - 2.6 6.7 30.0 3 6.5 30.0 1.0 1 0 0 1 1 1 0 Raftlin PA26 PF04636.13 CDJ49678.1 - 2.7 6.8 25.1 3.1 6.6 25.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Dapper PF15268.6 CDJ49678.1 - 3 6.6 38.9 3.3 6.4 38.9 1.0 1 0 0 1 1 1 0 Dapper DUF2151 PF10221.9 CDJ49678.1 - 3.5 6.1 22.3 4.2 5.8 22.3 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator PAT1 PF09770.9 CDJ49678.1 - 4 5.6 63.2 4.7 5.3 63.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WTX PF09422.10 CDJ49678.1 - 4.2 6.3 26.8 4.8 6.1 26.8 1.1 1 0 0 1 1 1 0 WTX protein NPR3 PF03666.13 CDJ49678.1 - 4.3 6.0 34.3 5.4 5.7 34.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MRP-S31 PF15433.6 CDJ49678.1 - 4.7 6.8 35.8 5.9 6.5 35.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 MCM_bind PF09739.9 CDJ49678.1 - 6.1 5.2 30.5 7.6 4.9 30.5 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PNISR PF15996.5 CDJ49678.1 - 6.6 7.0 42.8 8.5 6.6 42.8 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR PMSI1 PF15322.6 CDJ49678.1 - 7.3 5.9 24.5 9.4 5.6 24.5 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF4386 PF14329.6 CDJ49678.1 - 7.4 6.4 18.8 1.6e+04 -4.5 18.8 2.3 1 1 0 1 1 0 0 Domain of unknown function (DUF4386) Hamartin PF04388.12 CDJ49678.1 - 7.9 5.0 33.3 8.8 4.9 33.3 1.0 1 0 0 1 1 1 0 Hamartin protein Membralin PF09746.9 CDJ49678.1 - 9 5.2 23.9 12 4.9 23.9 1.2 1 0 0 1 1 1 0 Tumour-associated protein Exonuc_VII_L PF02601.15 CDJ49678.1 - 9.7 5.7 39.7 11 5.5 39.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TraV PF09676.10 CDJ49679.1 - 0.00065 20.7 7.2 0.00071 20.6 7.2 1.1 1 0 0 1 1 1 1 Type IV conjugative transfer system lipoprotein (TraV) DUF1180 PF06679.12 CDJ49679.1 - 0.14 12.5 8.1 0.17 12.3 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DprA_WH PF17782.1 CDJ49679.1 - 1.4 9.1 8.7 2.9 8.1 8.7 1.8 1 1 0 1 1 1 0 DprA winged helix domain Rad51 PF08423.11 CDJ49680.1 - 5.6e-108 360.0 0.0 3.5e-107 357.4 0.0 1.9 2 0 0 2 2 2 1 Rad51 RecA PF00154.21 CDJ49680.1 - 2.1e-06 27.4 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CDJ49680.1 - 6.6e-06 25.8 0.3 1.9e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain HHH_5 PF14520.6 CDJ49680.1 - 0.00058 20.4 0.2 0.0013 19.3 0.2 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain TFIIA PF03153.13 CDJ49680.1 - 0.019 15.0 15.1 0.024 14.7 15.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_24 PF13479.6 CDJ49680.1 - 0.019 14.7 0.0 0.09 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2722 PF10846.8 CDJ49680.1 - 0.032 13.2 8.2 0.04 12.9 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) LETM1 PF07766.13 CDJ49680.1 - 0.04 13.3 4.4 0.065 12.6 4.4 1.3 1 0 0 1 1 1 0 LETM1-like protein OmpH PF03938.14 CDJ49680.1 - 0.046 14.1 21.8 0.35 11.2 22.1 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Mitoc_mL59 PF18126.1 CDJ49680.1 - 0.052 13.9 3.9 0.091 13.1 3.9 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 CSRNP_N PF16019.5 CDJ49680.1 - 0.083 12.8 5.1 0.14 12.1 5.1 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF4770 PF15994.5 CDJ49680.1 - 0.085 13.1 8.1 0.13 12.5 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Cortex-I_coil PF09304.10 CDJ49680.1 - 0.086 13.1 4.9 0.22 11.8 4.9 1.6 1 0 0 1 1 1 0 Cortexillin I, coiled coil Presenilin PF01080.17 CDJ49680.1 - 1.1 8.0 3.5 1.3 7.7 3.5 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ49680.1 - 1.2 8.7 20.8 1.7 8.2 20.8 1.2 1 0 0 1 1 1 0 Spt20 family DUF4407 PF14362.6 CDJ49680.1 - 3.1 7.1 7.1 4.7 6.5 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDE_Tnp_ISAZ013 PF07592.11 CDJ49680.1 - 3.2 6.6 7.7 6.5 5.6 7.7 1.4 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Androgen_recep PF02166.16 CDJ49680.1 - 3.6 6.3 20.9 5.8 5.6 20.9 1.3 1 0 0 1 1 1 0 Androgen receptor Sec23_BS PF08033.12 CDJ49681.1 - 1.3e-29 102.7 0.0 2e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CDJ49681.1 - 1.2e-24 86.1 0.5 2e-24 85.4 0.5 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 CDJ49681.1 - 2.4e-07 30.6 0.1 1.1e-06 28.4 0.1 2.1 2 1 0 2 2 2 1 Gelsolin repeat Ribosomal_60s PF00428.19 CDJ49681.1 - 0.71 10.5 9.0 1.4 9.6 9.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein 60KD_IMP PF02096.20 CDJ49682.1 - 0.00094 19.1 5.0 0.0013 18.7 5.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein EMC3_TMCO1 PF01956.16 CDJ49682.1 - 0.0046 16.7 1.8 0.0069 16.1 1.8 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like RLL PF10036.9 CDJ49682.1 - 0.0066 16.3 8.0 0.0082 16.0 8.0 1.2 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein RskA PF10099.9 CDJ49682.1 - 0.0091 16.3 0.1 0.012 15.9 0.1 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Nop53 PF07767.11 CDJ49682.1 - 0.02 14.3 11.7 0.026 13.9 11.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) eIF-3_zeta PF05091.12 CDJ49682.1 - 0.024 13.7 10.3 0.027 13.5 10.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Gaa1 PF04114.14 CDJ49682.1 - 0.069 12.2 11.9 0.096 11.7 11.9 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Tim54 PF11711.8 CDJ49682.1 - 0.084 11.6 7.9 0.092 11.5 7.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MAM33 PF02330.16 CDJ49682.1 - 0.14 12.1 17.2 0.49 10.3 17.2 1.9 1 1 0 1 1 1 0 Mitochondrial glycoprotein XRN_M PF17846.1 CDJ49682.1 - 0.28 10.1 3.9 0.26 10.2 3.9 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DivIC PF04977.15 CDJ49682.1 - 0.31 10.9 12.5 0.44 10.3 12.5 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF2681 PF10883.8 CDJ49682.1 - 0.34 11.3 17.7 0.77 10.2 17.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Peptidase_S49_N PF08496.10 CDJ49682.1 - 0.6 10.2 6.3 0.18 11.9 2.4 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4770 PF15994.5 CDJ49682.1 - 0.65 10.2 10.0 1.1 9.5 10.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Arv1 PF04161.13 CDJ49682.1 - 0.73 10.0 8.9 1.5 8.9 8.9 1.6 1 1 0 1 1 1 0 Arv1-like family DUF3169 PF11368.8 CDJ49682.1 - 0.73 9.3 9.6 0.12 11.8 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) TMEM51 PF15345.6 CDJ49682.1 - 0.96 9.2 24.0 2.3 8.0 24.0 1.8 1 1 0 1 1 1 0 Transmembrane protein 51 Draxin PF15550.6 CDJ49682.1 - 1.2 8.9 14.1 1.8 8.4 14.1 1.2 1 0 0 1 1 1 0 Draxin Glt_symporter PF03616.14 CDJ49682.1 - 1.8 7.1 6.1 2.8 6.5 6.1 1.3 1 1 0 1 1 1 0 Sodium/glutamate symporter FAM150 PF15129.6 CDJ49682.1 - 3.1 7.9 11.0 7.9 6.7 11.0 1.6 1 0 0 1 1 1 0 FAM150 family Chorein_N PF12624.7 CDJ49682.1 - 5 7.3 9.4 4.3 7.5 5.4 2.4 2 0 0 2 2 2 0 N-terminal region of Chorein or VPS13 GREB1 PF15782.5 CDJ49682.1 - 8.4 3.4 37.5 11 3.0 37.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EphA2_TM PF14575.6 CDJ49682.1 - 9.5 7.2 16.7 6.9e+02 1.2 16.2 3.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CDC27 PF09507.10 CDJ49683.1 - 1.1 8.5 55.5 1.4 8.2 55.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SARG PF15385.6 CDJ49683.1 - 1.7 7.8 58.0 2.2 7.4 58.0 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein BUD22 PF09073.10 CDJ49684.1 - 8.1e-05 22.1 5.6 8.1e-05 22.1 5.6 11.4 8 3 0 10 10 10 4 BUD22 Lin-8 PF03353.15 CDJ49684.1 - 0.00049 19.8 16.3 0.00049 19.8 16.3 14.3 10 5 0 11 11 11 1 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ49684.1 - 0.00054 18.7 27.3 0.00054 18.7 27.3 12.4 10 3 1 11 11 11 2 Macoilin family SR-25 PF10500.9 CDJ49684.1 - 0.0018 18.0 6.6 0.0018 18.0 6.6 21.1 17 6 3 21 21 21 2 Nuclear RNA-splicing-associated protein LTV PF04180.14 CDJ49684.1 - 0.0023 17.8 4.1 0.0023 17.8 4.1 10.9 11 3 0 12 12 12 1 Low temperature viability protein Pkinase PF00069.25 CDJ49686.1 - 1.1e-09 38.0 0.0 8.4e-09 35.2 0.0 5.4 6 0 0 6 6 6 2 Protein kinase domain BUD22 PF09073.10 CDJ49686.1 - 0.00026 20.5 0.8 0.00026 20.5 0.8 13.9 8 3 3 12 12 12 4 BUD22 GET2 PF08690.10 CDJ49687.1 - 0.55 9.9 25.7 0.68 9.6 25.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 FUSC PF04632.12 CDJ49687.1 - 3.6 6.0 24.7 4.1 5.8 24.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family ThiS PF02597.20 CDJ49687.1 - 4.5 8.0 8.1 1.5 9.5 1.2 2.4 1 1 1 2 2 2 0 ThiS family Sporozoite_P67 PF05642.11 CDJ49689.1 - 0.0075 14.4 5.1 0.0089 14.2 5.1 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DDHD PF02862.17 CDJ49689.1 - 0.028 14.6 5.9 0.036 14.2 5.9 1.1 1 0 0 1 1 1 0 DDHD domain DUF4614 PF15391.6 CDJ49689.1 - 0.15 12.0 16.4 0.18 11.8 16.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) NST1 PF13945.6 CDJ49689.1 - 0.38 10.8 15.8 0.51 10.4 15.8 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4813 PF16072.5 CDJ49689.1 - 0.69 9.5 40.8 0.8 9.3 40.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Alg14 PF08660.11 CDJ49689.1 - 0.73 9.8 3.8 0.82 9.6 3.8 1.1 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like Apt1 PF10351.9 CDJ49689.1 - 0.82 8.4 10.8 0.86 8.4 10.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.16 CDJ49689.1 - 1.5 8.8 7.2 1.6 8.8 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 CDJ49689.1 - 1.8 7.3 9.2 1.9 7.2 9.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Spt20 PF12090.8 CDJ49689.1 - 2.9 7.5 18.2 3.7 7.1 18.2 1.1 1 0 0 1 1 1 0 Spt20 family SLC12 PF03522.15 CDJ49689.1 - 6.4 5.7 8.5 7.6 5.4 8.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ49689.1 - 7.7 6.0 10.5 11 5.5 10.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1635 PF07795.11 CDJ49689.1 - 8.8 6.1 20.9 31 4.3 20.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) DUF4834 PF16118.5 CDJ49690.1 - 1.2e-05 26.1 1.5 1.3e-05 26.0 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF3824 PF12868.7 CDJ49690.1 - 0.00066 20.4 2.4 0.00075 20.2 2.4 1.1 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) DUF1980 PF09323.10 CDJ49690.1 - 0.0014 18.6 0.8 0.0014 18.6 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) LYRIC PF15686.5 CDJ49690.1 - 0.003 17.2 1.3 0.0034 17.0 1.3 1.0 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family FHIPEP PF00771.20 CDJ49690.1 - 0.0035 15.9 3.1 0.0035 15.9 3.1 1.0 1 0 0 1 1 1 1 FHIPEP family Androgen_recep PF02166.16 CDJ49690.1 - 0.01 14.7 21.5 0.011 14.6 21.5 1.0 1 0 0 1 1 1 0 Androgen receptor MAPEG PF01124.18 CDJ49690.1 - 0.014 15.3 0.9 0.015 15.2 0.9 1.1 1 0 0 1 1 1 0 MAPEG family DUF2700 PF10912.8 CDJ49690.1 - 0.014 15.4 0.0 0.016 15.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) RskA PF10099.9 CDJ49690.1 - 0.015 15.6 15.5 0.019 15.3 15.5 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Trp_oprn_chp PF09534.10 CDJ49690.1 - 0.016 15.0 2.5 0.02 14.7 2.5 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CD20 PF04103.15 CDJ49690.1 - 0.018 15.1 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 CD20-like family Ctr PF04145.15 CDJ49690.1 - 0.02 15.5 1.4 0.02 15.5 1.4 1.0 1 0 0 1 1 1 0 Ctr copper transporter family LEA_3 PF03242.13 CDJ49690.1 - 0.027 15.2 0.5 0.029 15.1 0.5 1.1 1 0 0 1 1 1 0 Late embryogenesis abundant protein Synuclein PF01387.17 CDJ49690.1 - 0.035 14.3 2.5 0.043 14.0 2.5 1.0 1 0 0 1 1 1 0 Synuclein DUF3357 PF11837.8 CDJ49690.1 - 0.037 14.5 1.6 0.05 14.1 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) CcmD PF04995.14 CDJ49690.1 - 0.04 14.0 4.3 0.04 14.0 4.3 2.7 1 1 2 3 3 2 0 Heme exporter protein D (CcmD) V_ATPase_I PF01496.19 CDJ49690.1 - 0.055 11.4 3.9 0.056 11.4 3.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3592 PF12158.8 CDJ49690.1 - 0.069 13.2 0.4 0.074 13.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) DUF4179 PF13786.6 CDJ49690.1 - 0.093 13.2 0.2 0.11 13.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF2946 PF11162.8 CDJ49690.1 - 0.1 13.3 5.9 0.12 13.1 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) MTABC_N PF16185.5 CDJ49690.1 - 0.12 11.8 0.8 0.14 11.6 0.8 1.2 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region SID-1_RNA_chan PF13965.6 CDJ49690.1 - 0.12 10.8 0.3 0.12 10.8 0.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Choline_transpo PF04515.12 CDJ49690.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Plasma-membrane choline transporter DUF3402 PF11882.8 CDJ49690.1 - 0.16 11.0 7.1 0.16 11.0 7.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) CLN3 PF02487.17 CDJ49690.1 - 0.2 10.7 1.6 0.2 10.7 1.6 1.0 1 0 0 1 1 1 0 CLN3 protein PigN PF04987.14 CDJ49690.1 - 0.23 10.3 1.7 0.25 10.2 1.7 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF2227 PF09988.9 CDJ49690.1 - 0.45 10.4 2.2 0.46 10.4 2.2 1.1 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) ABC2_membrane_2 PF12679.7 CDJ49690.1 - 0.48 9.7 3.8 0.53 9.5 3.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1180 PF06679.12 CDJ49690.1 - 1.2 9.5 4.8 1.7 9.0 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TFIIA PF03153.13 CDJ49690.1 - 2 8.3 22.6 2.1 8.3 22.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ49690.1 - 2.5 6.7 22.9 2.5 6.7 22.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ49690.1 - 3.3 7.3 28.6 3.7 7.1 28.6 1.0 1 0 0 1 1 1 0 Spt20 family Ribonuc_red_sm PF00268.21 CDJ49691.1 - 9e-113 376.4 1.9 1.2e-112 375.9 1.9 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain BROMI PF14961.6 CDJ49691.1 - 0.013 12.9 0.1 0.018 12.5 0.1 1.1 1 0 0 1 1 1 0 Broad-minded protein TPR_1 PF00515.28 CDJ49692.1 - 2.8e-05 23.7 0.4 0.14 12.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ49692.1 - 0.0019 18.2 11.6 0.11 12.7 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Ribosomal_60s PF00428.19 CDJ49692.1 - 0.0074 16.8 8.8 0.0074 16.8 8.8 7.4 6 2 1 7 7 7 1 60s Acidic ribosomal protein TPR_17 PF13431.6 CDJ49692.1 - 0.024 15.0 1.4 0.23 11.9 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TERB2 PF15101.6 CDJ49693.1 - 0.083 12.9 13.4 0.083 12.9 13.4 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Tim54 PF11711.8 CDJ49693.1 - 0.47 9.2 12.0 0.47 9.2 12.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spt20 PF12090.8 CDJ49693.1 - 0.52 9.9 27.8 0.6 9.7 27.8 1.1 1 0 0 1 1 1 0 Spt20 family EPL1 PF10513.9 CDJ49693.1 - 0.64 10.4 13.8 0.71 10.2 13.8 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like TMEM51 PF15345.6 CDJ49693.1 - 0.82 9.5 11.2 0.97 9.2 11.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 TRAP_alpha PF03896.16 CDJ49693.1 - 1.1 8.4 5.5 1.2 8.3 5.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.6 CDJ49693.1 - 1.3 8.6 8.6 1.6 8.4 8.6 1.1 1 0 0 1 1 1 0 FAM176 family CPSF100_C PF13299.6 CDJ49693.1 - 1.4 9.1 9.2 1.6 8.9 9.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 CDJ49693.1 - 1.6 7.7 9.8 1.6 7.6 9.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Mem_trans PF03547.18 CDJ49693.1 - 1.7 7.0 4.4 1.6 7.0 4.4 1.0 1 0 0 1 1 1 0 Membrane transport protein TFIIA PF03153.13 CDJ49693.1 - 1.7 8.5 25.7 1.8 8.5 25.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 CDJ49693.1 - 1.8 7.3 7.9 1.9 7.2 7.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DDHD PF02862.17 CDJ49693.1 - 1.9 8.6 10.5 2.2 8.4 10.5 1.1 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ49693.1 - 1.9 7.3 12.8 2.1 7.3 12.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 CDJ49693.1 - 1.9 7.8 11.8 2 7.8 11.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Membralin PF09746.9 CDJ49693.1 - 2.6 7.0 5.1 2.6 7.0 5.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein Spore_coat_CotO PF14153.6 CDJ49693.1 - 3 7.7 16.6 3.4 7.6 16.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF4770 PF15994.5 CDJ49693.1 - 3.1 8.0 11.6 3.6 7.8 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) UPF0560 PF10577.9 CDJ49693.1 - 3.2 6.1 14.9 3.4 6.0 14.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Lin-8 PF03353.15 CDJ49693.1 - 3.2 7.2 14.9 3.4 7.2 14.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 CDJ49693.1 - 3.2 4.7 14.0 3.3 4.7 14.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DDRGK PF09756.9 CDJ49693.1 - 3.7 7.1 17.8 4.6 6.8 17.8 1.0 1 0 0 1 1 1 0 DDRGK domain FancD2 PF14631.6 CDJ49693.1 - 3.8 4.8 8.8 4.2 4.6 8.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Presenilin PF01080.17 CDJ49693.1 - 4.2 6.0 17.0 4.9 5.8 17.0 1.0 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 CDJ49693.1 - 4.2 6.7 10.4 4.9 6.5 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1980 PF09323.10 CDJ49693.1 - 4.4 7.2 7.7 4.9 7.0 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Sec62 PF03839.16 CDJ49693.1 - 4.6 6.7 9.1 5.1 6.5 9.1 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 PAT1 PF09770.9 CDJ49693.1 - 5.1 5.2 18.8 5.7 5.1 18.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Plasmodium_Vir PF05795.11 CDJ49693.1 - 5.6 6.3 9.9 5.9 6.2 9.9 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CLN3 PF02487.17 CDJ49693.1 - 5.6 5.9 8.4 5.5 5.9 8.4 1.0 1 0 0 1 1 1 0 CLN3 protein Band_3_cyto PF07565.13 CDJ49693.1 - 5.8 6.6 11.3 6.7 6.4 11.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4820 PF16091.5 CDJ49693.1 - 6.7 6.0 11.2 7.9 5.8 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DNApol_Exo PF18136.1 CDJ49693.1 - 7.1 5.7 11.2 8.2 5.5 11.2 1.0 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Neur_chan_memb PF02932.16 CDJ49693.1 - 8 6.4 11.3 7.8 6.5 11.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF3_subunit PF08597.10 CDJ49693.1 - 9.1 6.1 16.1 10 5.9 16.1 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 CDJ49693.1 - 9.4 4.4 11.6 10 4.3 11.6 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.6 CDJ49694.1 - 6.4 6.7 35.8 6.8 6.6 35.8 1.0 1 0 0 1 1 1 0 Protein Family FAM60A SR-25 PF10500.9 CDJ49696.1 - 0.00012 21.8 28.4 0.00016 21.4 28.4 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 CDJ49696.1 - 0.0025 17.4 33.6 0.0029 17.2 33.6 1.0 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist FCP1_C PF09309.10 CDJ49696.1 - 0.0042 17.0 22.8 0.0051 16.7 22.8 1.2 1 0 0 1 1 1 1 FCP1, C-terminal Cwf_Cwc_15 PF04889.12 CDJ49696.1 - 0.011 15.4 20.6 0.013 15.2 20.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 CDJ49696.1 - 0.017 15.1 59.7 0.02 14.9 59.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1645 PF07816.11 CDJ49696.1 - 0.058 14.0 20.3 0.082 13.5 20.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Macoilin PF09726.9 CDJ49696.1 - 0.068 11.7 28.0 0.076 11.6 28.0 1.0 1 0 0 1 1 1 0 Macoilin family Asparaginase_2 PF01112.18 CDJ49696.1 - 0.074 12.1 10.1 0.095 11.7 10.1 1.2 1 0 0 1 1 1 0 Asparaginase BASP1 PF05466.12 CDJ49696.1 - 0.13 12.2 18.6 0.15 12.0 18.6 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Apt1 PF10351.9 CDJ49696.1 - 0.27 10.0 29.9 0.33 9.7 29.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 CDJ49696.1 - 0.3 8.8 20.1 0.38 8.5 20.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SWI-SNF_Ssr4 PF08549.10 CDJ49696.1 - 0.32 9.6 30.3 0.38 9.3 30.3 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) GREB1 PF15782.5 CDJ49696.1 - 0.41 7.7 34.8 0.45 7.6 34.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TAF4 PF05236.14 CDJ49696.1 - 0.46 10.2 25.8 0.65 9.7 25.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Herpes_pp85 PF04637.12 CDJ49696.1 - 0.54 8.6 6.9 0.6 8.5 6.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Myc_N PF01056.18 CDJ49696.1 - 0.56 10.1 19.9 0.74 9.7 19.9 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NST1 PF13945.6 CDJ49696.1 - 0.57 10.3 36.5 0.74 9.9 36.5 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator PAP1 PF08601.10 CDJ49696.1 - 0.66 9.6 30.2 0.8 9.4 30.2 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 SRP-alpha_N PF04086.13 CDJ49696.1 - 0.83 9.5 27.1 0.99 9.3 27.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3295 PF11702.8 CDJ49696.1 - 0.97 8.7 34.7 1.2 8.4 34.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Plasmodium_Vir PF05795.11 CDJ49696.1 - 1.2 8.4 19.6 1.4 8.2 19.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Na_trans_assoc PF06512.13 CDJ49696.1 - 1.2 9.3 19.0 1.5 9.1 19.0 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated PIG-S PF10510.9 CDJ49696.1 - 1.3 7.8 27.4 1.4 7.7 27.4 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Peptidase_S64 PF08192.11 CDJ49696.1 - 1.3 7.4 33.2 1.5 7.2 33.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4407 PF14362.6 CDJ49696.1 - 1.3 8.3 21.8 1.5 8.1 21.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4638 PF15472.6 CDJ49696.1 - 1.6 8.4 19.6 2 8.1 19.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF1387 PF07139.11 CDJ49696.1 - 1.6 8.4 29.4 1.9 8.1 29.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF853 PF05872.12 CDJ49696.1 - 2 6.9 15.7 2.2 6.8 15.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3292 PF11696.8 CDJ49696.1 - 2.1 6.6 15.2 2.5 6.4 15.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF2151 PF10221.9 CDJ49696.1 - 2.6 6.5 19.5 3.1 6.3 19.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator SPX PF03105.19 CDJ49696.1 - 2.8 7.8 32.5 3.3 7.5 32.5 1.0 1 0 0 1 1 1 0 SPX domain Usp PF00582.26 CDJ49696.1 - 2.8 8.4 8.1 3.4 8.2 7.4 1.6 1 1 0 1 1 1 0 Universal stress protein family CDC45 PF02724.14 CDJ49696.1 - 3.2 5.9 25.1 4.2 5.5 25.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2126 PF09899.9 CDJ49696.1 - 3.3 5.6 14.8 3.5 5.6 14.8 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Miga PF10265.9 CDJ49696.1 - 3.4 6.5 25.3 3.8 6.4 25.3 1.0 1 0 0 1 1 1 0 Mitoguardin DUF4192 PF13830.6 CDJ49696.1 - 3.6 7.6 9.4 3.8 7.5 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF966 PF06136.13 CDJ49696.1 - 4.7 6.8 29.6 5 6.7 29.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SLC12 PF03522.15 CDJ49696.1 - 5.1 6.0 29.7 5.9 5.8 29.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SAGA-Tad1 PF12767.7 CDJ49696.1 - 5.3 6.7 25.2 6.6 6.4 25.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3395 PF11875.8 CDJ49696.1 - 5.8 6.8 27.0 9.9 6.0 27.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Membralin PF09746.9 CDJ49696.1 - 5.9 5.8 21.1 6.6 5.7 21.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein Cellulose_synt PF03552.14 CDJ49696.1 - 7.1 5.0 11.0 7 5.0 11.0 1.1 1 0 0 1 1 1 0 Cellulose synthase PAT1 PF09770.9 CDJ49696.1 - 9.3 4.4 45.0 11 4.1 45.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SUIM_assoc PF16619.5 CDJ49697.1 - 0.00048 20.1 2.1 0.00048 20.1 2.1 2.1 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF3464 PF11947.8 CDJ49697.1 - 0.0046 16.7 0.4 0.0082 15.9 0.4 1.4 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 Spt20 PF12090.8 CDJ49697.1 - 0.0053 16.4 5.2 0.0067 16.1 5.2 1.3 1 0 0 1 1 1 1 Spt20 family PAT1 PF09770.9 CDJ49697.1 - 0.36 9.0 9.2 0.35 9.1 9.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MscS_TM PF12794.7 CDJ49697.1 - 0.77 8.6 8.8 0.07 12.0 3.5 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 IATP PF04568.12 CDJ49697.1 - 3.2 8.2 13.2 0.69 10.4 9.1 2.1 2 1 1 3 3 3 0 Mitochondrial ATPase inhibitor, IATP MSP1_C PF07462.11 CDJ49697.1 - 9.6 4.8 6.8 15 4.1 6.8 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF5423 PF17461.2 CDJ49698.1 - 2.5 6.9 16.3 3 6.6 16.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Sec1 PF00995.23 CDJ49699.1 - 2e-67 228.7 0.0 6.7e-67 227.0 0.0 1.8 1 1 0 1 1 1 1 Sec1 family TFIIA PF03153.13 CDJ49699.1 - 8.2e-05 22.8 32.2 0.027 14.5 8.7 3.2 3 0 0 3 3 3 3 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ49699.1 - 0.071 11.8 35.6 0.28 9.8 4.1 3.2 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal ANAPC_CDC26 PF10471.9 CDJ49699.1 - 0.11 13.3 40.6 0.11 13.3 4.8 4.9 5 0 0 5 5 5 0 Anaphase-promoting complex APC subunit CDC26 DUF4834 PF16118.5 CDJ49699.1 - 0.19 12.7 9.6 8.7 7.4 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ49699.1 - 0.22 10.4 30.3 0.15 11.0 3.8 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ49699.1 - 0.29 11.2 51.1 0.13 12.3 3.6 5.3 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ49699.1 - 2.2 8.6 37.4 12 6.2 0.2 5.6 4 1 1 5 5 5 0 Anti-sigma-K factor rskA UPF0121 PF03661.13 CDJ49700.1 - 9.6e-12 44.8 0.3 1.6e-11 44.1 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Ephrin_rec_like PF07699.13 CDJ49701.1 - 8.9e-27 92.6 112.4 9.9e-08 31.6 4.3 11.4 12 0 0 12 12 12 8 Putative ephrin-receptor like Uso1_p115_C PF04871.13 CDJ49701.1 - 0.0076 16.6 5.2 0.017 15.5 5.2 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region PAN_4 PF14295.6 CDJ49701.1 - 0.0079 16.1 1.3 0.028 14.3 0.2 2.6 2 0 0 2 2 2 1 PAN domain Collagen PF01391.18 CDJ49701.1 - 0.023 14.5 24.0 0.063 13.1 24.0 1.8 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) HALZ PF02183.18 CDJ49701.1 - 0.093 13.0 0.9 0.2 11.9 0.9 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper He_PIG PF05345.12 CDJ49701.1 - 0.47 10.7 2.0 1.1 9.5 0.3 2.4 2 0 0 2 2 2 0 Putative Ig domain Amino_oxidase PF01593.24 CDJ49702.1 - 3.7e-26 92.4 6.0 4.1e-17 62.6 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ49702.1 - 7.9e-13 48.4 0.2 2.6e-12 46.8 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDJ49702.1 - 4.7e-06 25.9 3.8 8.5e-06 25.1 3.8 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CDJ49702.1 - 8.8e-06 25.1 0.4 1.6e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDJ49702.1 - 1.6e-05 24.6 0.1 1.6e-05 24.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CDJ49702.1 - 2.1e-05 24.1 0.7 2.1e-05 24.1 0.7 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CDJ49702.1 - 0.00019 20.8 0.5 0.0004 19.7 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CDJ49702.1 - 0.00071 18.9 0.2 0.0014 17.9 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CDJ49702.1 - 0.0011 19.5 0.2 0.003 18.1 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ49702.1 - 0.0053 15.5 0.8 0.0053 15.5 0.8 2.3 2 0 0 2 2 2 1 HI0933-like protein PHD PF00628.29 CDJ49702.1 - 0.096 12.6 6.2 0.026 14.4 1.1 2.5 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 CDJ49702.1 - 0.15 12.4 4.9 0.088 13.2 1.8 2.3 2 0 0 2 2 2 0 Ring finger domain MCRA PF06100.11 CDJ49702.1 - 4.5 5.9 7.3 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 MCRA family PRP1_N PF06424.12 CDJ49703.1 - 2.3e-52 177.3 2.9 3e-43 147.7 0.8 2.8 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CDJ49703.1 - 4.5e-29 98.6 30.9 0.001 19.7 0.5 14.8 7 3 9 16 16 15 8 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ49703.1 - 4.1e-20 72.1 12.9 0.00067 20.1 0.1 9.0 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ49703.1 - 1.1e-09 38.7 12.7 0.00023 21.8 0.0 8.2 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ49703.1 - 3.4e-08 33.0 9.6 4.9 7.5 0.2 9.9 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ49703.1 - 1.8e-06 27.7 2.6 12 6.4 0.0 8.3 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ49703.1 - 2.2e-05 24.5 6.9 0.39 11.2 0.0 8.8 12 2 1 13 13 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ49703.1 - 4.6e-05 23.0 0.0 1.7 8.4 0.0 4.8 5 0 0 5 5 5 2 TPR repeat TPR_12 PF13424.6 CDJ49703.1 - 0.00012 22.3 9.2 1.4 9.3 0.1 6.8 7 1 1 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ49703.1 - 0.00015 21.9 5.1 0.22 11.8 0.2 5.1 4 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 CDJ49703.1 - 0.00031 19.9 8.5 0.13 11.2 0.1 4.1 2 1 2 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) Suf PF05843.14 CDJ49703.1 - 0.00035 20.6 0.0 6.2 6.7 0.1 4.9 3 3 0 3 3 3 1 Suppressor of forked protein (Suf) DUF3808 PF10300.9 CDJ49703.1 - 0.001 17.9 1.3 0.61 8.7 0.1 4.1 4 1 1 5 5 5 1 Protein of unknown function (DUF3808) TPR_9 PF13371.6 CDJ49703.1 - 0.012 15.7 7.6 1.3 9.2 0.2 5.4 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.9 CDJ49703.1 - 0.041 13.6 16.1 0.034 13.9 4.9 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat-like domain Tho2 PF11262.8 CDJ49703.1 - 0.17 11.0 1.6 0.77 8.9 1.3 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TPR_1 PF00515.28 CDJ49703.1 - 0.23 11.3 1.2 3.4 7.7 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ49703.1 - 0.43 11.3 17.8 17 6.3 0.0 8.2 10 0 0 10 10 9 0 Tetratricopeptide repeat SCAN PF02023.17 CDJ49703.1 - 1.2 9.0 6.4 3.8 7.4 0.1 3.9 3 1 1 4 4 3 0 SCAN domain DUF1104 PF06518.11 CDJ49704.1 - 0.26 11.7 2.4 0.63 10.4 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) YscO PF07321.12 CDJ49704.1 - 0.96 9.4 3.7 0.85 9.6 0.8 2.2 1 1 1 2 2 2 0 Type III secretion protein YscO Apolipoprotein PF01442.18 CDJ49704.1 - 1.5 8.6 6.4 9.8 6.0 6.5 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain WD40_4 PF16300.5 CDJ49705.1 - 2.5e-19 68.9 0.0 4.6e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CDJ49705.1 - 1.8e-13 50.7 6.4 1.1e-06 29.2 0.0 4.3 4 0 0 4 4 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ49705.1 - 4.7e-10 39.6 0.1 0.0019 18.5 0.1 4.0 3 1 1 4 4 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 CDJ49705.1 - 1e-06 28.5 0.0 2.6e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) DUF812 PF05667.11 CDJ49705.1 - 0.00019 20.5 14.3 0.00027 20.0 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Leu_zip PF15294.6 CDJ49705.1 - 0.0011 18.5 15.8 0.0017 17.9 15.8 1.2 1 0 0 1 1 1 1 Leucine zipper eIF2A PF08662.11 CDJ49705.1 - 0.0044 16.9 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A BLOC1_2 PF10046.9 CDJ49705.1 - 0.0063 16.8 18.6 0.43 10.9 4.2 2.5 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 CDJ49705.1 - 0.011 16.0 9.5 0.011 16.0 9.5 3.5 1 1 4 5 5 5 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 CDJ49705.1 - 0.014 15.4 8.3 0.17 11.9 8.3 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 CDJ49705.1 - 0.017 15.2 17.8 0.36 10.9 2.2 3.0 1 1 2 3 3 3 0 TolA binding protein trimerisation Exonuc_VII_L PF02601.15 CDJ49705.1 - 0.05 13.2 7.1 0.081 12.5 7.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit IFT57 PF10498.9 CDJ49705.1 - 0.089 11.7 12.1 0.12 11.3 12.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HOOK PF05622.12 CDJ49705.1 - 0.089 10.9 21.8 0.19 9.8 21.6 1.5 1 1 0 1 1 1 0 HOOK protein Phage_GP20 PF06810.11 CDJ49705.1 - 0.12 12.2 21.9 1.4 8.8 16.6 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Tropomyosin_1 PF12718.7 CDJ49705.1 - 0.22 11.6 27.5 2.7 8.1 15.5 2.2 1 1 1 2 2 2 0 Tropomyosin like Lebercilin PF15619.6 CDJ49705.1 - 0.42 10.2 22.5 0.84 9.3 22.5 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease FlaC_arch PF05377.11 CDJ49705.1 - 0.45 10.9 12.2 2.6 8.5 0.1 3.9 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) ERM PF00769.19 CDJ49705.1 - 0.67 9.7 22.0 0.99 9.2 22.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Fib_alpha PF08702.10 CDJ49705.1 - 0.8 9.9 13.1 0.52 10.5 7.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4201 PF13870.6 CDJ49705.1 - 0.95 9.2 17.8 1.5 8.6 17.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Atg14 PF10186.9 CDJ49705.1 - 1.2 8.2 15.5 1.8 7.6 15.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BRE1 PF08647.11 CDJ49705.1 - 1.4 9.0 21.5 7.2 6.8 20.2 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Spc29 PF17082.5 CDJ49705.1 - 1.4 8.7 10.3 11 5.8 4.5 2.5 1 1 1 2 2 2 0 Spindle Pole Component 29 CHDCT2 PF08074.11 CDJ49705.1 - 1.5 9.0 8.0 2.6 8.2 8.0 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain GAS PF13851.6 CDJ49705.1 - 1.8 7.9 24.5 1.5 8.2 20.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 CDJ49705.1 - 2.6 8.2 25.3 3.1 8.0 7.6 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF5082 PF16888.5 CDJ49705.1 - 2.7 8.3 15.3 5.8 7.2 15.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) RPW8 PF05659.11 CDJ49705.1 - 3.6 7.3 9.8 9.6 5.9 3.4 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4407 PF14362.6 CDJ49705.1 - 3.8 6.8 18.6 6.7 6.0 18.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 CDJ49705.1 - 4.2 5.2 9.5 6.7 4.5 9.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 CDJ49705.1 - 4.5 7.5 27.1 0.57 10.4 13.5 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Macoilin PF09726.9 CDJ49705.1 - 5.1 5.5 13.6 7.3 5.0 13.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF724 PF05266.14 CDJ49705.1 - 5.4 6.8 17.2 28 4.4 17.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Med4 PF10018.9 CDJ49705.1 - 5.4 6.6 17.0 0.32 10.7 2.3 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Fmp27_WPPW PF10359.9 CDJ49705.1 - 5.7 5.7 10.5 8.9 5.0 10.5 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FAM76 PF16046.5 CDJ49705.1 - 6.8 5.9 10.9 12 5.2 10.9 1.3 1 0 0 1 1 1 0 FAM76 protein NPV_P10 PF05531.12 CDJ49705.1 - 6.9 7.2 14.5 8.8 6.9 1.4 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 CDJ49705.1 - 7.3 7.1 29.6 11 6.6 14.7 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 CDJ49705.1 - 7.5 6.6 28.4 72 3.5 8.8 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Swi5 PF07061.11 CDJ49705.1 - 8.8 6.5 18.2 3.2 7.9 0.5 3.9 1 1 1 3 3 3 0 Swi5 Spc7 PF08317.11 CDJ49705.1 - 9.8 5.0 25.3 76 2.0 25.6 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 CDJ49705.1 - 10 6.2 13.5 2.3 8.3 6.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 CDJ49706.1 - 0.62 9.9 4.0 0.65 9.8 2.1 2.0 2 0 0 2 2 2 0 Septum formation initiator WD40 PF00400.32 CDJ49707.1 - 1e-14 54.6 5.7 0.036 14.9 0.1 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ49707.1 - 0.00014 22.1 0.2 1 9.7 0.0 4.3 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain V-ATPase_G PF03179.15 CDJ49710.1 - 1.6e-24 86.4 8.6 2e-24 86.1 8.6 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit HrpE PF06188.12 CDJ49710.1 - 0.0027 17.6 3.3 0.0054 16.6 3.3 1.4 1 1 0 1 1 1 1 HrpE/YscL/FliH and V-type ATPase subunit E ATP-synt_B PF00430.18 CDJ49710.1 - 0.021 14.9 10.2 0.021 14.9 10.2 1.5 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) GspL_C PF12693.7 CDJ49710.1 - 0.04 13.7 2.1 0.052 13.4 2.1 1.1 1 0 0 1 1 1 0 GspL periplasmic domain V-ATPase_G_2 PF16999.5 CDJ49710.1 - 0.28 11.6 12.7 0.48 10.9 12.7 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit WD40 PF00400.32 CDJ49711.1 - 8.8e-26 89.7 7.0 4.6e-06 27.3 0.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ49711.1 - 6e-07 29.7 0.0 1.5 9.2 0.0 4.7 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ49711.1 - 0.061 12.3 0.5 14 4.5 0.2 3.0 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 CDJ49711.1 - 0.24 9.7 0.0 8 4.6 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ribosomal_S5 PF00333.20 CDJ49712.1 - 1.7e-29 101.6 0.4 3.9e-29 100.4 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CDJ49712.1 - 2.3e-23 81.4 0.0 4.4e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 CDJ49712.1 - 4.5 7.9 9.9 11 6.6 9.9 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PRR20 PF15708.5 CDJ49712.1 - 9 6.1 5.9 19 5.1 4.2 2.0 2 0 0 2 2 2 0 Proline-rich protein family 20 Ribosomal_S17_N PF16205.5 CDJ49713.1 - 1.6e-28 98.9 0.2 3.3e-28 97.9 0.2 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CDJ49713.1 - 1.4e-23 82.8 1.5 2e-23 82.3 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 EELM2 PF15863.5 CDJ49714.1 - 5e-76 254.6 0.1 7e-76 254.1 0.1 1.2 1 0 0 1 1 1 1 Extended EGL-27 and MTA1 homology domain PHD PF00628.29 CDJ49714.1 - 2.4e-08 33.8 6.4 2.4e-08 33.8 6.4 1.9 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 CDJ49714.1 - 0.013 15.2 5.7 0.082 12.5 2.9 2.8 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 CDJ49714.1 - 4.6 6.9 9.7 0.31 10.6 4.2 2.0 2 0 0 2 2 2 0 PHD-finger Nop25 PF09805.9 CDJ49715.1 - 1.4e-13 51.5 8.9 2e-13 51.0 8.9 1.1 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) DUF5526 PF17664.1 CDJ49715.1 - 0.0016 18.0 6.4 0.079 12.5 4.9 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5526) Ribosomal_L37 PF08561.10 CDJ49715.1 - 0.16 12.5 5.2 0.17 12.4 2.2 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Delta_lysin PF05372.11 CDJ49716.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Delta lysin family RabGAP-TBC PF00566.18 CDJ49717.1 - 1.6e-10 41.0 8.1 5.4e-08 32.8 3.4 4.8 5 1 1 6 6 6 2 Rab-GTPase-TBC domain Rhodanese PF00581.20 CDJ49717.1 - 0.066 13.7 0.0 0.42 11.1 0.0 2.4 2 0 0 2 2 2 0 Rhodanese-like domain SUIM_assoc PF16619.5 CDJ49717.1 - 0.19 11.8 0.0 0.19 11.8 0.0 12.2 9 3 1 10 10 10 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 CDJ49718.1 - 3e-16 59.0 0.2 8.4e-16 57.6 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 CDJ49718.1 - 1.9e-14 54.1 0.5 3.4e-14 53.3 0.5 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G ComGF PF15980.5 CDJ49718.1 - 0.059 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative Competence protein ComGF PHM7_cyt PF14703.6 CDJ49718.1 - 0.06 13.6 1.5 8.6 6.6 0.1 3.2 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter SUIM_assoc PF16619.5 CDJ49719.1 - 8.5e-05 22.6 0.3 8.5e-05 22.6 0.3 6.8 5 1 0 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 DA1-like PF12315.8 CDJ49720.1 - 4.1e-06 26.3 1.5 4.1e-06 26.3 1.5 4.5 4 1 0 5 5 5 2 Protein DA1 Spt20 PF12090.8 CDJ49720.1 - 0.00012 21.8 11.8 0.00041 20.0 3.2 5.7 5 1 0 5 5 5 2 Spt20 family SR-25 PF10500.9 CDJ49720.1 - 0.00067 19.3 4.4 0.00067 19.3 4.4 6.6 7 0 0 7 7 7 2 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ49720.1 - 0.0013 17.8 1.2 0.0013 17.8 1.2 6.4 5 1 0 5 5 5 3 Protein of unknown function (DUF2722) LIM PF00412.22 CDJ49720.1 - 0.12 12.7 0.1 0.12 12.7 0.1 4.3 3 1 1 4 4 4 0 LIM domain EPL1 PF10513.9 CDJ49720.1 - 0.47 10.8 39.7 3.9 7.9 0.2 5.0 5 0 0 5 5 5 0 Enhancer of polycomb-like Pet20 PF08692.10 CDJ49720.1 - 5.2 7.8 21.0 11 6.8 3.0 4.3 4 0 0 4 4 4 0 Mitochondrial protein Pet20 EF-hand_1 PF00036.32 CDJ49721.1 - 4.1e-07 29.1 0.4 0.0044 16.5 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ49721.1 - 7e-07 29.6 0.9 0.034 14.6 0.0 3.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ49721.1 - 1.3e-06 27.9 0.1 0.00061 19.5 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ49721.1 - 1.6e-05 24.2 0.3 0.016 14.7 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ49721.1 - 0.039 13.8 0.1 8 6.4 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair Dockerin_1 PF00404.18 CDJ49721.1 - 0.044 14.0 2.6 13 6.1 0.0 3.4 3 0 0 3 3 3 0 Dockerin type I domain FapA PF03961.13 CDJ49721.1 - 0.24 10.0 11.2 0.39 9.3 9.9 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A MRP-S27 PF10037.9 CDJ49721.1 - 0.87 8.4 24.5 1.4 7.7 24.5 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 CSG2 PF16965.5 CDJ49721.1 - 7.5 5.4 8.3 13 4.6 8.3 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator TFIIA PF03153.13 CDJ49722.1 - 0.00022 21.4 59.2 0.02 14.9 24.1 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ49722.1 - 0.00067 18.7 10.2 0.00067 18.7 10.2 3.3 3 1 0 3 3 1 1 Protein of unknown function (DUF2722) Connexin PF00029.19 CDJ49722.1 - 0.0013 18.6 15.0 0.02 14.6 0.1 2.3 2 0 0 2 2 2 1 Connexin EOS1 PF12326.8 CDJ49722.1 - 0.0018 18.2 5.2 0.12 12.2 0.4 2.4 2 0 0 2 2 2 2 N-glycosylation protein PRCC PF10253.9 CDJ49722.1 - 0.002 18.9 9.7 0.002 18.9 9.7 3.1 2 1 0 2 2 1 1 Mitotic checkpoint regulator, MAD2B-interacting DUF4834 PF16118.5 CDJ49722.1 - 0.0034 18.3 0.3 0.0034 18.3 0.3 3.1 3 0 0 3 3 2 1 Domain of unknown function (DUF4834) Velvet PF11754.8 CDJ49722.1 - 0.0039 17.2 19.5 0.036 14.0 5.6 2.3 2 0 0 2 2 2 2 Velvet factor SpoIIP PF07454.11 CDJ49722.1 - 0.0061 16.1 18.1 0.1 12.0 7.4 2.2 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) FAM60A PF15396.6 CDJ49722.1 - 0.0065 16.5 13.9 0.53 10.3 0.3 2.3 2 0 0 2 2 2 2 Protein Family FAM60A GEMIN8 PF15348.6 CDJ49722.1 - 0.0092 16.3 12.9 0.0092 16.3 12.9 2.6 2 1 0 2 2 1 1 Gemini of Cajal bodies-associated protein 8 CDC45 PF02724.14 CDJ49722.1 - 0.011 14.1 10.8 0.26 9.6 0.1 2.1 2 0 0 2 2 2 0 CDC45-like protein MecA PF05389.12 CDJ49722.1 - 0.013 15.2 10.9 0.22 11.1 0.7 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF2828 PF11443.8 CDJ49722.1 - 0.019 13.1 16.8 0.27 9.3 8.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ49722.1 - 0.02 13.7 27.0 0.0051 15.6 24.0 1.5 1 1 1 2 2 2 0 Presenilin LMBR1 PF04791.16 CDJ49722.1 - 0.028 13.3 1.7 0.037 12.9 1.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4746 PF15928.5 CDJ49722.1 - 0.034 13.6 18.4 0.13 11.7 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) TRAP_alpha PF03896.16 CDJ49722.1 - 0.039 13.2 5.9 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Lin-8 PF03353.15 CDJ49722.1 - 0.049 13.2 20.1 0.21 11.1 0.4 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF913 PF06025.12 CDJ49722.1 - 0.067 12.2 10.9 0.54 9.2 0.7 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CCSAP PF15748.5 CDJ49722.1 - 0.07 13.3 30.1 0.13 12.4 13.1 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated EPL1 PF10513.9 CDJ49722.1 - 0.073 13.4 0.8 0.073 13.4 0.8 2.6 3 0 0 3 3 2 0 Enhancer of polycomb-like MMR1 PF08505.10 CDJ49722.1 - 0.097 13.0 23.3 0.08 13.2 2.2 2.4 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Endostatin PF06482.11 CDJ49722.1 - 0.14 11.6 20.4 0.37 10.2 9.1 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin CSG2 PF16965.5 CDJ49722.1 - 0.19 10.6 6.3 2.8 6.8 0.2 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator DUF2370 PF10176.9 CDJ49722.1 - 0.2 11.3 5.8 2.1 7.9 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Afi1 PF07792.12 CDJ49722.1 - 0.27 11.7 18.4 2.6 8.5 1.2 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking AF-4 PF05110.13 CDJ49722.1 - 0.32 9.1 25.6 0.34 9.0 14.2 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein TCP PF03634.13 CDJ49722.1 - 0.35 11.4 23.7 0.035 14.7 3.4 2.6 3 0 0 3 3 2 0 TCP family transcription factor PIP5K PF01504.18 CDJ49722.1 - 0.38 9.9 20.2 0.77 8.9 8.7 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase SARAF PF06682.12 CDJ49722.1 - 0.56 9.8 19.1 6.1 6.4 18.8 2.3 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF737 PF05300.11 CDJ49722.1 - 0.58 10.5 25.4 0.21 12.0 10.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Ant_C PF05586.11 CDJ49722.1 - 0.63 10.7 0.1 0.63 10.7 0.1 3.3 2 1 0 2 2 1 0 Anthrax receptor C-terminus region Band_3_cyto PF07565.13 CDJ49722.1 - 0.85 9.4 21.4 0.47 10.2 0.6 2.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain OATP PF03137.20 CDJ49722.1 - 1.4 7.1 10.6 4 5.6 0.3 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4770 PF15994.5 CDJ49722.1 - 1.5 9.0 24.4 3.5 7.8 5.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Renin_r PF07850.14 CDJ49722.1 - 1.5 9.4 6.1 24 5.6 1.2 2.8 2 0 0 2 2 2 0 Renin receptor-like protein CAF1 PF04857.20 CDJ49722.1 - 2 7.5 14.8 1.3 8.2 1.8 2.1 2 0 0 2 2 2 0 CAF1 family ribonuclease Peptidase_S64 PF08192.11 CDJ49722.1 - 2.1 6.7 13.7 3.4 6.0 0.3 2.1 2 0 0 2 2 2 0 Peptidase family S64 DUF4471 PF14740.6 CDJ49722.1 - 2.9 7.0 15.5 6.6 5.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) SID-1_RNA_chan PF13965.6 CDJ49722.1 - 3.9 5.8 10.7 20 3.5 10.9 1.7 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 THOC2_N PF16134.5 CDJ49722.1 - 4.5 5.8 15.4 0.22 10.1 4.2 2.3 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus CLN3 PF02487.17 CDJ49722.1 - 4.7 6.2 19.8 5.2 6.0 5.0 2.3 2 1 0 2 2 2 0 CLN3 protein DUF4820 PF16091.5 CDJ49722.1 - 5.1 6.4 20.5 0.13 11.6 1.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4820) FAM91_C PF14648.6 CDJ49722.1 - 6.3 5.5 10.3 7.5 5.3 0.1 2.1 2 0 0 2 2 2 0 FAM91 C-terminus Dishevelled PF02377.15 CDJ49722.1 - 6.6 7.2 20.1 9 6.7 1.0 3.2 3 0 0 3 3 3 0 Dishevelled specific domain RICTOR_N PF14664.6 CDJ49722.1 - 6.6 5.6 10.0 1.9 7.4 0.8 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term DUF1772 PF08592.11 CDJ49722.1 - 9.3 6.6 19.6 0.17 12.2 9.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) NAM-associated PF14303.6 CDJ49723.1 - 0.07 13.9 0.0 0.07 13.9 0.0 7.3 2 2 4 6 6 6 0 No apical meristem-associated C-terminal domain RNA_pol_Rpc4 PF05132.14 CDJ49724.1 - 0.17 12.3 3.6 0.26 11.7 3.6 1.4 1 1 0 1 1 1 0 RNA polymerase III RPC4 SOG2 PF10428.9 CDJ49724.1 - 3.8 6.6 15.7 4.1 6.5 15.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Mitofilin PF09731.9 CDJ49724.1 - 6.2 5.5 15.1 6.4 5.5 15.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ISP3_C PF18045.1 CDJ49725.1 - 4.9e-41 139.0 0.0 6.8e-41 138.6 0.0 1.2 1 0 0 1 1 1 1 ISP3 C-terminal ISP1_C PF18161.1 CDJ49725.1 - 7.5e-38 128.8 0.0 1.2e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 ISP1 C-terminal NopRA1 PF16201.5 CDJ49726.1 - 1.6e-06 27.8 0.7 1.6e-06 27.8 0.7 3.2 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Pex16 PF08610.10 CDJ49726.1 - 0.16 11.1 2.2 1.8 7.6 0.0 3.3 3 0 0 3 3 3 0 Peroxisomal membrane protein (Pex16) HHH_8 PF14716.6 CDJ49728.1 - 0.044 14.2 0.0 0.6 10.5 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF5536 PF17688.1 CDJ49731.1 - 0.57 10.0 5.9 0.46 10.4 1.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5536) CobA_CobO_BtuR PF02572.15 CDJ49731.1 - 1.2 9.3 5.4 3.4 7.9 5.4 1.8 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP FPL PF09758.9 CDJ49733.1 - 9.1e-58 194.5 5.1 1.4e-57 193.8 5.1 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein BTB PF00651.31 CDJ49734.1 - 6.1e-07 29.7 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Mannosyl_trans PF05007.13 CDJ49735.1 - 2.2e-59 201.4 10.8 3.6e-59 200.7 10.8 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 CDJ49735.1 - 9.6e-16 57.8 1.4 9.6e-16 57.8 1.4 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 CDJ49735.1 - 0.0004 20.2 9.6 0.0004 20.2 9.6 2.8 2 1 1 3 3 3 1 Glycosyltransferase family 87 DUF1045 PF06299.12 CDJ49735.1 - 0.086 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) ALG3 PF05208.13 CDJ49735.1 - 0.21 11.0 6.8 1.1 8.6 0.1 2.9 3 0 0 3 3 3 0 ALG3 protein Myosin_head PF00063.21 CDJ49736.1 - 8.5e-31 106.9 0.0 2.7e-22 78.8 0.0 2.8 2 1 0 2 2 2 2 Myosin head (motor domain) RCC1 PF00415.18 CDJ49736.1 - 3.5e-25 88.4 13.6 3.5e-09 37.1 0.1 5.7 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ49736.1 - 6.2e-08 32.3 0.5 6.2e-08 32.3 0.5 5.4 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 CDJ49736.1 - 1.5 8.8 12.3 0.76 9.7 1.1 3.8 3 0 0 3 3 3 0 IQ calmodulin-binding motif RIFIN PF02009.16 CDJ49737.1 - 0.00029 20.8 13.0 0.00036 20.5 13.0 1.1 1 0 0 1 1 1 1 Rifin Activator_LAG-3 PF11498.8 CDJ49737.1 - 0.0021 17.1 12.5 0.0027 16.8 12.5 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Sporozoite_P67 PF05642.11 CDJ49737.1 - 0.0025 16.0 1.8 0.0029 15.8 1.8 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen TFIIA PF03153.13 CDJ49737.1 - 0.0054 16.8 14.6 0.0065 16.5 14.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ49737.1 - 0.0066 15.5 6.4 0.0082 15.1 6.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) MecA PF05389.12 CDJ49737.1 - 0.042 13.5 0.9 0.047 13.3 0.9 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Draxin PF15550.6 CDJ49737.1 - 0.052 13.4 3.0 0.052 13.4 3.0 1.1 1 0 0 1 1 1 0 Draxin SUIM_assoc PF16619.5 CDJ49737.1 - 0.054 13.6 12.9 0.094 12.8 12.9 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 CDJ49737.1 - 0.1 12.9 4.0 0.13 12.7 4.0 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Spt20 PF12090.8 CDJ49737.1 - 0.18 11.4 16.8 0.22 11.1 16.8 1.1 1 0 0 1 1 1 0 Spt20 family FRQ PF09421.10 CDJ49737.1 - 0.19 9.7 7.1 0.24 9.4 7.1 1.1 1 0 0 1 1 1 0 Frequency clock protein DUF2981 PF11200.8 CDJ49737.1 - 0.75 9.5 6.2 1 9.1 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) WTX PF09422.10 CDJ49737.1 - 1.6 7.7 8.4 1.7 7.7 8.4 1.2 1 0 0 1 1 1 0 WTX protein RLL PF10036.9 CDJ49737.1 - 1.6 8.5 14.5 2.1 8.1 14.5 1.2 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein DUF4834 PF16118.5 CDJ49737.1 - 1.7 9.6 6.0 2.5 9.1 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CPSF100_C PF13299.6 CDJ49737.1 - 3.3 7.9 7.9 5.3 7.2 7.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TERB2 PF15101.6 CDJ49737.1 - 4.9 7.2 10.0 6.5 6.8 10.0 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Herpes_UL74 PF07982.12 CDJ49737.1 - 7.2 5.5 7.3 9.5 5.0 7.3 1.2 1 0 0 1 1 1 0 Herpes UL74 glycoproteins Roughex PF06020.11 CDJ49737.1 - 7.9 5.5 9.1 9.7 5.2 9.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein XRN_M PF17846.1 CDJ49737.1 - 8.1 5.3 7.2 9.7 5.0 7.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain ubiquitin PF00240.23 CDJ49738.1 - 2e-10 40.3 0.0 9.2e-10 38.1 0.0 2.3 1 0 0 1 1 1 1 Ubiquitin family DUF4179 PF13786.6 CDJ49738.1 - 0.013 16.0 10.9 2.3 8.7 0.7 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4179) RskA PF10099.9 CDJ49738.1 - 0.02 15.2 8.8 0.02 15.2 8.8 7.2 3 1 1 5 5 5 0 Anti-sigma-K factor rskA Chromo PF00385.24 CDJ49739.1 - 1.6e-06 27.9 0.3 3.7e-06 26.7 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ABG_transport PF03806.13 CDJ49739.1 - 0.69 8.1 2.3 1.2 7.3 2.3 1.3 1 0 0 1 1 1 0 AbgT putative transporter family DARPP-32 PF05395.12 CDJ49740.1 - 0.34 11.1 16.3 0.39 10.9 16.3 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Spt20 PF12090.8 CDJ49740.1 - 0.69 9.5 16.0 0.98 9.0 16.0 1.3 1 0 0 1 1 1 0 Spt20 family TFIIS_M PF07500.14 CDJ49741.1 - 1.9e-08 34.8 2.2 1.9e-08 34.8 2.2 3.9 5 0 0 5 5 5 1 Transcription factor S-II (TFIIS), central domain SR-25 PF10500.9 CDJ49741.1 - 0.0042 16.7 3.2 0.0042 16.7 3.2 11.6 6 4 2 9 9 9 3 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ49742.1 - 6.5e-05 23.3 3.8 6.5e-05 23.3 3.8 13.3 2 2 8 10 10 10 2 Anti-sigma-K factor rskA MAP65_ASE1 PF03999.12 CDJ49743.1 - 0.082 11.6 20.7 0.092 11.4 20.7 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RPOL_N PF14700.6 CDJ49743.1 - 0.097 12.0 12.4 0.11 11.9 12.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal SRP-alpha_N PF04086.13 CDJ49743.1 - 0.17 11.8 21.3 0.19 11.6 21.3 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2126 PF09899.9 CDJ49743.1 - 0.18 9.8 2.7 0.21 9.6 2.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Peptidase_M29 PF02073.15 CDJ49743.1 - 0.18 10.5 4.6 0.22 10.3 4.6 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Macoilin PF09726.9 CDJ49743.1 - 0.24 9.9 25.8 0.28 9.7 25.8 1.0 1 0 0 1 1 1 0 Macoilin family AF-4 PF05110.13 CDJ49743.1 - 0.42 8.7 45.3 0.46 8.5 4.2 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DUF4175 PF13779.6 CDJ49743.1 - 0.52 8.2 24.3 0.63 7.9 24.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SPX PF03105.19 CDJ49743.1 - 0.69 9.8 22.5 0.99 9.2 22.5 1.2 1 0 0 1 1 1 0 SPX domain SURF6 PF04935.12 CDJ49743.1 - 1.2 8.9 23.5 2.7 7.8 23.5 1.6 1 1 0 1 1 1 0 Surfeit locus protein 6 FliD_N PF02465.18 CDJ49743.1 - 2 9.1 29.7 2.5 8.8 2.9 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Connexin PF00029.19 CDJ49743.1 - 2.5 7.8 12.2 0.71 9.6 9.1 1.6 1 1 1 2 2 2 0 Connexin Peptidase_S64 PF08192.11 CDJ49743.1 - 3 6.2 25.2 3.6 6.0 25.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.9 CDJ49743.1 - 3.2 5.9 23.7 4 5.6 23.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ49743.1 - 3.5 7.2 57.1 1 8.9 37.5 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein BAT2_N PF07001.11 CDJ49743.1 - 3.6 8.0 32.0 1.6 9.2 20.4 2.0 2 0 0 2 2 2 0 BAT2 N-terminus Nop25 PF09805.9 CDJ49743.1 - 4.4 7.8 17.7 1.2 9.6 11.4 2.0 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) PI3K_1B_p101 PF10486.9 CDJ49743.1 - 4.9 4.8 23.6 5.7 4.6 23.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pheromone PF08015.11 CDJ49743.1 - 5.3 8.1 17.7 2.7 9.1 2.1 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone XRCC4 PF06632.12 CDJ49743.1 - 6 5.6 20.8 7.6 5.3 20.8 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 CIAPIN1 PF05093.13 CDJ49743.1 - 6.4 7.3 9.7 7.5 7.1 7.4 2.0 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis SSP160 PF06933.11 CDJ49743.1 - 7 4.7 23.7 2.4 6.3 9.6 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 DUF755 PF05501.11 CDJ49743.1 - 7.3 6.9 65.1 0.25 11.6 7.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF755) Lin-8 PF03353.15 CDJ49743.1 - 7.4 6.0 29.6 3.9 6.9 1.5 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF2722 PF10846.8 CDJ49743.1 - 7.9 5.3 36.5 0.24 10.3 26.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SAGA-Tad1 PF12767.7 CDJ49744.1 - 1.3 8.7 19.5 1.4 8.6 19.5 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Hid1 PF12722.7 CDJ49744.1 - 3.3 5.7 20.1 3.2 5.8 20.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SWIRM-assoc_2 PF16496.5 CDJ49744.1 - 3.6 6.4 19.0 4.1 6.2 19.0 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Zip PF02535.22 CDJ49744.1 - 4.3 6.5 10.3 4.5 6.4 10.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ49744.1 - 5.6 5.6 29.1 6.1 5.5 29.1 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ49744.1 - 8.6 6.1 24.4 9.4 6.0 24.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PHO4 PF01384.20 CDJ49745.1 - 5.2e-22 78.3 9.6 1.7e-21 76.7 9.6 1.7 1 1 0 1 1 1 1 Phosphate transporter family Adeno_PV PF03910.13 CDJ49745.1 - 5.6 5.6 8.7 7 5.2 8.7 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV Senescence_reg PF04520.13 CDJ49746.1 - 0.011 16.6 6.9 0.017 16.0 6.9 1.2 1 0 0 1 1 1 0 Senescence regulator FHIPEP PF00771.20 CDJ49746.1 - 0.014 13.9 3.8 0.018 13.5 3.8 1.2 1 0 0 1 1 1 0 FHIPEP family Chorion_2 PF03964.15 CDJ49746.1 - 0.042 14.7 18.6 0.89 10.4 4.0 2.3 2 0 0 2 2 2 0 Chorion family 2 Shadoo PF14999.6 CDJ49746.1 - 0.079 13.1 11.2 0.72 10.0 8.2 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective PAT1 PF09770.9 CDJ49746.1 - 0.14 10.4 22.1 0.15 10.3 22.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sin_N PF04801.13 CDJ49746.1 - 0.24 10.6 20.0 0.28 10.3 20.0 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region MMR1 PF08505.10 CDJ49746.1 - 0.29 11.4 10.8 0.31 11.3 10.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Dynactin_p62 PF05502.13 CDJ49746.1 - 0.38 9.5 8.9 0.46 9.2 8.9 1.1 1 0 0 1 1 1 0 Dynactin p62 family CCSAP PF15748.5 CDJ49746.1 - 0.73 10.0 15.0 0.98 9.5 15.0 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Spore_III_AF PF09581.10 CDJ49746.1 - 1.1 9.2 9.7 1.2 9.2 8.4 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Ribosomal_60s PF00428.19 CDJ49746.1 - 1.2 9.7 22.1 2.4 8.8 4.2 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Presenilin PF01080.17 CDJ49746.1 - 1.5 7.5 11.7 1.6 7.4 11.7 1.1 1 0 0 1 1 1 0 Presenilin LCIB_C_CA PF18599.1 CDJ49746.1 - 1.6 8.0 10.3 1.4 8.2 7.0 2.0 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Lin-8 PF03353.15 CDJ49746.1 - 1.9 8.0 17.4 2.9 7.4 17.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist VIT1 PF01988.19 CDJ49746.1 - 3.8 7.3 9.3 6.5 6.6 9.3 1.4 1 0 0 1 1 1 0 VIT family FUSC PF04632.12 CDJ49746.1 - 4.1 5.8 14.5 5.5 5.4 14.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ndc1_Nup PF09531.10 CDJ49746.1 - 4.5 5.8 13.4 4.8 5.8 13.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4518 PF15008.6 CDJ49746.1 - 5.6 6.1 13.4 8.2 5.5 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) MDM10 PF12519.8 CDJ49746.1 - 6.6 5.5 9.9 8.1 5.2 9.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF3138 PF11336.8 CDJ49747.1 - 0.65 8.5 3.5 1 7.9 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PAT1 PF09770.9 CDJ49748.1 - 4.9e-05 21.8 33.6 4.9e-05 21.8 33.6 9.8 5 3 2 8 8 8 1 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.8 CDJ49748.1 - 0.00025 20.1 6.8 0.00025 20.1 6.8 14.2 10 3 6 17 17 17 1 Transcriptional activator LAG-3 RskA PF10099.9 CDJ49748.1 - 0.00042 20.7 10.1 0.00042 20.7 10.1 23.1 5 4 12 18 18 18 4 Anti-sigma-K factor rskA Lin-8 PF03353.15 CDJ49748.1 - 0.0032 17.1 28.4 0.0032 17.1 28.4 12.8 9 3 3 12 12 12 2 Ras-mediated vulval-induction antagonist CLN3 PF02487.17 CDJ49749.1 - 3.8e-07 29.5 11.5 4.1e-07 29.4 11.5 1.0 1 0 0 1 1 1 1 CLN3 protein Connexin PF00029.19 CDJ49749.1 - 0.00041 20.2 11.5 0.00051 19.9 11.5 1.2 1 0 0 1 1 1 1 Connexin RR_TM4-6 PF06459.12 CDJ49749.1 - 0.00049 20.0 15.2 0.00053 19.9 15.2 1.0 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Kei1 PF08552.11 CDJ49749.1 - 0.00053 19.9 8.9 0.00066 19.6 8.9 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Presenilin PF01080.17 CDJ49749.1 - 0.00056 18.8 21.4 0.00068 18.5 21.4 1.1 1 0 0 1 1 1 1 Presenilin FAM76 PF16046.5 CDJ49749.1 - 0.00091 18.7 18.4 0.0011 18.4 18.4 1.1 1 0 0 1 1 1 1 FAM76 protein Afi1 PF07792.12 CDJ49749.1 - 0.00096 19.6 15.5 0.0013 19.2 15.5 1.2 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Scs3p PF10261.9 CDJ49749.1 - 0.001 18.7 4.5 0.0012 18.5 4.5 1.0 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Zip PF02535.22 CDJ49749.1 - 0.0018 17.5 10.1 0.0024 17.2 10.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4366 PF14283.6 CDJ49749.1 - 0.0042 17.1 3.1 0.006 16.6 3.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Pex14_N PF04695.13 CDJ49749.1 - 0.0054 17.4 27.2 0.0083 16.8 27.2 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CSG2 PF16965.5 CDJ49749.1 - 0.0079 15.2 7.6 0.0091 15.0 7.6 1.1 1 0 0 1 1 1 1 Ceramide synthase regulator Nucleoside_tran PF01733.18 CDJ49749.1 - 0.0086 15.5 5.9 0.011 15.2 5.9 1.1 1 0 0 1 1 1 1 Nucleoside transporter FemAB PF02388.16 CDJ49749.1 - 0.0088 15.0 17.6 0.01 14.8 17.6 1.0 1 0 0 1 1 1 1 FemAB family DUF2370 PF10176.9 CDJ49749.1 - 0.012 15.3 7.8 0.014 15.1 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF913 PF06025.12 CDJ49749.1 - 0.014 14.4 8.2 0.016 14.3 8.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) EOS1 PF12326.8 CDJ49749.1 - 0.015 15.2 8.9 0.022 14.7 8.9 1.3 1 0 0 1 1 1 0 N-glycosylation protein FAM60A PF15396.6 CDJ49749.1 - 0.017 15.1 13.7 0.019 14.9 13.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Ureide_permease PF07168.11 CDJ49749.1 - 0.017 13.9 4.2 0.018 13.8 4.2 1.1 1 0 0 1 1 1 0 Ureide permease Orf78 PF06024.12 CDJ49749.1 - 0.018 15.3 4.3 0.018 15.3 4.3 2.1 1 1 1 2 2 1 0 Orf78 (ac78) LAP1C PF05609.12 CDJ49749.1 - 0.023 13.8 21.1 0.027 13.6 21.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PTR2 PF00854.21 CDJ49749.1 - 0.024 13.5 3.4 0.03 13.2 3.4 1.1 1 0 0 1 1 1 0 POT family RP-C_C PF11800.8 CDJ49749.1 - 0.03 14.4 13.6 0.035 14.2 13.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region PIP5K PF01504.18 CDJ49749.1 - 0.03 13.5 14.5 0.039 13.2 14.5 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase V_ATPase_I PF01496.19 CDJ49749.1 - 0.031 12.2 21.9 0.036 12.0 21.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PBP1_TM PF14812.6 CDJ49749.1 - 0.035 14.5 6.6 0.045 14.1 6.6 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NPR3 PF03666.13 CDJ49749.1 - 0.037 12.8 18.2 0.044 12.6 18.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HCO3_cotransp PF00955.21 CDJ49749.1 - 0.052 12.4 8.2 0.055 12.3 8.2 1.0 1 0 0 1 1 1 0 HCO3- transporter family MMM1 PF10296.9 CDJ49749.1 - 0.056 12.5 11.6 0.071 12.2 11.6 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DAG_kinase_N PF14513.6 CDJ49749.1 - 0.064 13.5 20.7 0.075 13.2 20.7 1.0 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF5308 PF17233.2 CDJ49749.1 - 0.074 13.3 16.7 0.1 12.8 16.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Serinc PF03348.15 CDJ49749.1 - 0.075 11.9 11.5 0.1 11.5 11.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CD20 PF04103.15 CDJ49749.1 - 0.083 13.0 8.1 0.94 9.5 8.1 1.9 1 1 0 1 1 1 0 CD20-like family 7tm_1 PF00001.21 CDJ49749.1 - 0.083 12.2 14.9 0.83 8.9 14.9 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Sec62 PF03839.16 CDJ49749.1 - 0.089 12.3 14.9 0.12 11.9 14.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Pannexin_like PF12534.8 CDJ49749.1 - 0.09 11.9 11.3 0.1 11.7 11.3 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Folate_carrier PF01770.18 CDJ49749.1 - 0.09 11.5 9.7 0.11 11.2 9.7 1.3 1 0 0 1 1 1 0 Reduced folate carrier DUF2828 PF11443.8 CDJ49749.1 - 0.093 10.8 20.6 0.11 10.6 20.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) HemX PF04375.14 CDJ49749.1 - 0.096 12.0 42.0 0.099 11.9 42.0 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Otopetrin PF03189.13 CDJ49749.1 - 0.11 11.3 13.1 0.13 11.0 13.1 1.1 1 0 0 1 1 1 0 Otopetrin CDC45 PF02724.14 CDJ49749.1 - 0.13 10.5 19.6 0.16 10.2 19.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Gti1_Pac2 PF09729.9 CDJ49749.1 - 0.14 12.3 18.7 0.17 12.0 18.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2464 PF10240.9 CDJ49749.1 - 0.14 11.7 11.6 0.16 11.5 11.6 1.0 1 0 0 1 1 1 0 Multivesicular body subunit 12 SpoIIP PF07454.11 CDJ49749.1 - 0.17 11.3 20.8 0.22 10.9 20.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2126 PF09899.9 CDJ49749.1 - 0.19 9.7 13.5 0.21 9.6 13.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Glyco_hydro_63 PF03200.16 CDJ49749.1 - 0.27 9.9 11.7 0.31 9.7 11.7 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain ABC2_membrane_3 PF12698.7 CDJ49749.1 - 0.3 10.1 5.2 0.37 9.8 5.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2072 PF09845.9 CDJ49749.1 - 0.31 11.3 15.2 0.46 10.8 15.2 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF789 PF05623.12 CDJ49749.1 - 0.36 10.5 13.6 0.42 10.3 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) NnrU PF07298.11 CDJ49749.1 - 0.44 10.0 2.1 1.6 8.2 2.1 1.8 1 1 0 1 1 1 0 NnrU protein Acatn PF13000.7 CDJ49749.1 - 0.52 8.7 4.3 0.63 8.5 4.3 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 NARP1 PF12569.8 CDJ49749.1 - 0.55 9.1 21.8 0.61 8.9 21.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CBP_BcsG PF11658.8 CDJ49749.1 - 0.58 8.5 18.7 0.68 8.3 18.7 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Pal1 PF08316.11 CDJ49749.1 - 0.65 10.8 11.3 0.86 10.4 11.3 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein MDFI PF15316.6 CDJ49749.1 - 0.65 10.1 11.6 0.89 9.6 11.6 1.3 1 0 0 1 1 1 0 MyoD family inhibitor TYW3 PF02676.14 CDJ49749.1 - 0.67 9.3 12.2 0.81 9.0 12.2 1.0 1 0 0 1 1 1 0 Methyltransferase TYW3 Membralin PF09746.9 CDJ49749.1 - 0.75 8.8 14.1 0.86 8.6 14.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein Ndc1_Nup PF09531.10 CDJ49749.1 - 0.84 8.2 14.8 0.95 8.1 14.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCDC53 PF10152.9 CDJ49749.1 - 0.85 10.0 21.7 1.2 9.5 21.7 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PPL5 PF18168.1 CDJ49749.1 - 0.97 8.7 15.4 1.1 8.5 15.4 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Rtf2 PF04641.12 CDJ49749.1 - 1.2 8.4 19.6 1.5 8.1 19.6 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger GNAT_acetyltr_2 PF13718.6 CDJ49749.1 - 1.3 8.4 13.0 2.1 7.7 13.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Ctr PF04145.15 CDJ49749.1 - 1.5 9.5 17.1 2.2 8.9 17.1 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Tim54 PF11711.8 CDJ49749.1 - 1.6 7.5 19.1 2 7.1 19.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1180 PF06679.12 CDJ49749.1 - 1.8 9.0 5.4 2.2 8.6 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) FliP PF00813.20 CDJ49749.1 - 2.4 8.0 10.8 2.8 7.8 10.8 1.1 1 0 0 1 1 1 0 FliP family Velvet PF11754.8 CDJ49749.1 - 2.5 8.0 23.6 3.1 7.7 23.6 1.1 1 0 0 1 1 1 0 Velvet factor Rrn6 PF10214.9 CDJ49749.1 - 2.5 6.5 30.8 2.8 6.3 30.8 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF2347 PF09804.9 CDJ49749.1 - 2.7 7.5 11.2 3.3 7.2 11.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) SelP_N PF04592.14 CDJ49749.1 - 2.7 7.3 29.3 3.3 7.0 29.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF908 PF06012.12 CDJ49749.1 - 3.1 7.1 19.5 3.7 6.9 19.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF3295 PF11702.8 CDJ49749.1 - 3.1 7.1 22.6 3.4 6.9 22.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Peptidase_S64 PF08192.11 CDJ49749.1 - 3.2 6.1 20.8 3.8 5.9 20.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Endostatin PF06482.11 CDJ49749.1 - 3.3 7.1 24.0 3.9 6.9 24.0 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Peptidase_M56 PF05569.11 CDJ49749.1 - 3.3 6.8 6.9 8.1 5.5 6.9 1.7 1 1 0 1 1 1 0 BlaR1 peptidase M56 CAF1 PF04857.20 CDJ49749.1 - 3.4 6.8 16.7 4 6.5 16.7 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease BORG_CEP PF14957.6 CDJ49749.1 - 3.4 8.8 16.1 4.4 8.5 16.1 1.1 1 0 0 1 1 1 0 Cdc42 effector SLC12 PF03522.15 CDJ49749.1 - 3.7 6.5 25.9 4.4 6.2 25.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4050 PF13259.6 CDJ49749.1 - 3.8 7.8 21.3 4.5 7.6 21.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Med19 PF10278.9 CDJ49749.1 - 4.7 7.1 21.4 5.8 6.8 21.4 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CobT PF06213.12 CDJ49749.1 - 4.9 6.5 33.2 6.7 6.0 33.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Fer4_22 PF17179.4 CDJ49749.1 - 5.3 8.0 14.6 7.4 7.5 14.6 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain FAM163 PF15069.6 CDJ49749.1 - 5.4 7.4 10.8 6.4 7.2 10.8 1.2 1 0 0 1 1 1 0 FAM163 family Peptidase_S15 PF02129.18 CDJ49749.1 - 5.4 6.5 19.3 6.6 6.2 19.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MCM_bind PF09739.9 CDJ49749.1 - 5.9 5.2 23.1 7.1 4.9 23.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4638 PF15472.6 CDJ49749.1 - 6.3 6.5 21.8 7.3 6.2 21.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF4064 PF13273.6 CDJ49749.1 - 6.6 7.1 12.6 1.6e+03 -0.6 12.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Paramyxo_ncap PF00973.19 CDJ49749.1 - 7.1 5.4 20.7 8.1 5.2 20.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein AF-4 PF05110.13 CDJ49749.1 - 8.4 4.3 29.9 9.2 4.2 29.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GET2 PF08690.10 CDJ49749.1 - 8.8 5.9 24.7 13 5.4 24.7 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Chorein_N PF12624.7 CDJ49750.1 - 8e-18 64.7 0.0 2.1e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CDJ49750.1 - 5.4e-16 58.9 0.1 1.1e-15 57.9 0.1 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CDJ49750.1 - 1.8e-11 43.9 0.0 3.6e-08 33.1 0.0 3.2 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 CDJ49750.1 - 1.1e-05 25.4 0.0 0.00079 19.3 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Senescence PF06911.12 CDJ49750.1 - 0.065 13.5 0.8 1.1 9.6 1.0 2.4 2 0 0 2 2 2 0 Senescence-associated protein IF4E PF01652.18 CDJ49751.1 - 3.2e-06 27.0 0.0 6.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Apt1 PF10351.9 CDJ49751.1 - 0.0017 17.3 1.7 0.0017 17.3 1.7 6.1 4 1 0 4 4 4 3 Golgi-body localisation protein domain V_ATPase_I PF01496.19 CDJ49752.1 - 0.005 14.8 4.8 0.0058 14.6 4.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family XRCC4 PF06632.12 CDJ49752.1 - 0.0052 15.7 2.3 0.0055 15.6 2.3 1.0 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 SARAF PF06682.12 CDJ49752.1 - 0.016 14.9 6.2 0.019 14.6 6.2 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CSG2 PF16965.5 CDJ49752.1 - 0.017 14.1 0.8 0.019 14.0 0.8 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator NPR1_interact PF15699.5 CDJ49752.1 - 0.017 15.7 6.2 0.023 15.3 6.2 1.1 1 0 0 1 1 1 0 NPR1 interacting BAF1_ABF1 PF04684.13 CDJ49752.1 - 0.026 13.6 4.6 0.031 13.4 4.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4366 PF14283.6 CDJ49752.1 - 0.037 14.1 2.3 0.045 13.8 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 CDJ49752.1 - 0.037 12.8 7.4 0.043 12.6 7.4 1.1 1 0 0 1 1 1 0 Presenilin DUF1180 PF06679.12 CDJ49752.1 - 0.041 14.3 4.9 0.055 13.9 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CLN3 PF02487.17 CDJ49752.1 - 0.054 12.5 3.0 0.056 12.5 3.0 1.0 1 0 0 1 1 1 0 CLN3 protein Gti1_Pac2 PF09729.9 CDJ49752.1 - 0.062 13.4 3.1 0.071 13.2 3.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family CCDC53 PF10152.9 CDJ49752.1 - 0.096 13.1 10.4 0.12 12.8 10.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Cadherin_C_2 PF16492.5 CDJ49752.1 - 0.14 12.9 3.0 0.41 11.4 3.0 1.7 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal IER PF05760.12 CDJ49752.1 - 0.17 12.2 11.7 0.18 12.0 11.7 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) Connexin PF00029.19 CDJ49752.1 - 0.18 11.5 1.7 0.25 11.1 1.7 1.2 1 0 0 1 1 1 0 Connexin Folliculin PF11704.8 CDJ49752.1 - 0.28 11.1 6.2 0.34 10.8 6.2 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport PAT1 PF09770.9 CDJ49752.1 - 0.29 9.3 18.4 0.33 9.2 18.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RskA PF10099.9 CDJ49752.1 - 0.3 11.4 18.7 0.83 9.9 18.6 1.6 1 1 1 2 2 2 0 Anti-sigma-K factor rskA TRAP_alpha PF03896.16 CDJ49752.1 - 0.4 9.9 6.6 1.1 8.4 6.9 1.5 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Serinc PF03348.15 CDJ49752.1 - 0.47 9.3 2.3 0.53 9.1 2.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) UPF0542 PF15086.6 CDJ49752.1 - 0.52 10.3 0.1 0.52 10.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 PIP5K PF01504.18 CDJ49752.1 - 0.58 9.3 5.9 0.7 9.1 5.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Kei1 PF08552.11 CDJ49752.1 - 0.59 10.0 3.2 0.78 9.6 3.2 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Neur_chan_memb PF02932.16 CDJ49752.1 - 0.74 9.8 6.0 0.88 9.6 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Scs3p PF10261.9 CDJ49752.1 - 0.8 9.2 3.6 1.1 8.7 3.6 1.3 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM FAM176 PF14851.6 CDJ49752.1 - 1 9.0 5.2 1.7 8.3 5.2 1.4 1 1 0 1 1 1 0 FAM176 family Ctr PF04145.15 CDJ49752.1 - 1.1 9.9 7.9 2 9.1 7.9 1.4 1 1 0 1 1 1 0 Ctr copper transporter family Ndc1_Nup PF09531.10 CDJ49752.1 - 1.2 7.8 6.7 1.6 7.4 6.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CcmH PF03918.14 CDJ49752.1 - 1.2 8.4 9.7 0.85 8.9 1.6 2.1 1 1 1 2 2 2 0 Cytochrome C biogenesis protein CobT PF06213.12 CDJ49752.1 - 1.6 8.1 17.5 2.2 7.6 17.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sec62 PF03839.16 CDJ49752.1 - 1.8 8.0 6.1 2.3 7.7 6.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 YABBY PF04690.13 CDJ49752.1 - 2.5 8.6 7.4 3.3 8.3 7.4 1.2 1 0 0 1 1 1 0 YABBY protein RR_TM4-6 PF06459.12 CDJ49752.1 - 2.6 7.8 10.6 3.1 7.6 10.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ49752.1 - 3.3 6.5 5.6 3.9 6.2 5.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter GRP PF07172.11 CDJ49752.1 - 3.8 8.2 6.5 25 5.6 6.5 1.9 1 1 0 1 1 1 0 Glycine rich protein family FAM60A PF15396.6 CDJ49752.1 - 4 7.4 6.4 5.1 7.1 6.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CDK2AP PF09806.9 CDJ49752.1 - 7.7 6.5 17.9 9.7 6.2 17.9 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4079 PF13301.6 CDJ49752.1 - 7.9 6.6 6.0 22 5.2 6.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) TFIIA PF03153.13 CDJ49752.1 - 9.2 6.1 35.5 11 5.9 35.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 CDJ49753.1 - 3 8.3 43.9 7.9 6.9 23.1 2.5 2 0 0 2 2 2 0 AAA domain Peptidase_S15 PF02129.18 CDJ49753.1 - 10 5.6 32.5 0.021 14.4 1.3 3.2 2 1 1 4 4 4 0 X-Pro dipeptidyl-peptidase (S15 family) HC2 PF07382.11 CDJ49755.1 - 3.7e-06 27.2 20.6 1.2e-05 25.5 20.6 1.8 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 HU-HIG PF18291.1 CDJ49755.1 - 0.82 9.8 11.2 4.9 7.3 0.7 2.6 1 1 1 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif EF-hand_14 PF17959.1 CDJ49755.1 - 4.6 7.6 10.8 11 6.5 2.0 2.8 1 1 2 3 3 3 0 EF-hand domain TFIIA PF03153.13 CDJ49756.1 - 0.00089 19.4 2.7 0.00089 19.4 2.7 8.6 6 2 1 8 8 8 4 Transcription factor IIA, alpha/beta subunit SURF2 PF05477.11 CDJ49757.1 - 0.41 10.3 30.0 0.53 9.9 30.0 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Enolase_C PF00113.22 CDJ49758.1 - 1.4e-140 467.7 0.2 2.1e-140 467.1 0.2 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CDJ49758.1 - 1.8e-51 173.7 0.5 1.8e-51 173.7 0.5 3.8 3 1 1 4 4 4 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CDJ49758.1 - 9.3e-08 31.9 0.0 9.3e-08 31.9 0.0 2.6 3 0 0 3 3 3 1 Enolase C-terminal domain-like EF-hand_7 PF13499.6 CDJ49758.1 - 6e-07 29.8 0.0 2.2e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ49758.1 - 9.7e-05 22.0 0.2 0.95 9.6 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDJ49758.1 - 0.00011 21.5 0.1 0.014 14.9 0.1 2.7 2 0 0 2 2 2 1 EF hand SR-25 PF10500.9 CDJ49758.1 - 0.00013 21.7 5.8 0.00013 21.7 5.8 6.2 5 1 2 7 7 7 1 Nuclear RNA-splicing-associated protein MAAL_C PF07476.11 CDJ49758.1 - 0.0026 17.0 0.1 0.0063 15.7 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus SUIM_assoc PF16619.5 CDJ49758.1 - 0.0032 17.5 2.4 0.0032 17.5 2.4 15.5 13 2 1 14 14 14 2 Unstructured region C-term to UIM in Ataxin3 EF-hand_8 PF13833.6 CDJ49758.1 - 0.063 13.1 0.1 0.57 10.1 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain pair tRNA_synthFbeta PF17759.1 CDJ49759.1 - 2.7e-26 92.3 0.3 8.3e-26 90.8 0.3 1.7 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 CDJ49759.1 - 4.7e-06 26.4 0.0 4.7e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 B3/4 domain Adaptin_N PF01602.20 CDJ49759.1 - 0.0011 17.6 0.0 0.0017 17.0 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region RNA_pol_Rpc4 PF05132.14 CDJ49759.1 - 0.087 13.3 2.0 0.2 12.1 2.0 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 B5 PF03484.15 CDJ49759.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase B5 domain DUF1682 PF07946.14 CDJ49759.1 - 2.9 7.0 8.3 4.7 6.3 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SpoIIP PF07454.11 CDJ49760.1 - 0.0037 16.8 6.5 0.0037 16.8 6.5 1.9 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) V_ATPase_I PF01496.19 CDJ49760.1 - 0.019 12.9 10.1 0.032 12.2 10.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ketoacyl-synt PF00109.26 CDJ49761.1 - 2.9e-84 282.6 0.0 9.4e-61 205.6 0.0 2.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CDJ49761.1 - 4.9e-36 123.3 0.1 1e-35 122.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 CDJ49761.1 - 2.5e-14 53.4 0.8 1.4e-10 41.4 0.0 2.8 3 0 0 3 3 3 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 CDJ49761.1 - 1.5e-06 28.6 0.0 4.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 CDJ49761.1 - 0.07 12.5 1.2 0.94 8.8 0.8 2.4 3 0 0 3 3 3 0 Thiolase, N-terminal domain DUF1126 PF06565.12 CDJ49762.1 - 2.1e-48 162.5 0.1 6.4e-27 93.4 0.0 2.6 2 0 0 2 2 2 2 DUF1126 PH-like domain EF-hand_7 PF13499.6 CDJ49762.1 - 4.3e-09 36.7 0.3 1.4e-08 35.0 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ49762.1 - 1.1e-07 30.9 1.0 0.00075 18.9 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ49762.1 - 1.2e-07 31.4 0.2 6e-07 29.2 0.3 2.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ49762.1 - 1.1e-06 28.1 0.5 0.086 12.8 0.0 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ49762.1 - 0.036 13.6 0.0 0.12 11.9 0.0 1.9 1 0 0 1 1 1 0 EF hand PIN_6 PF17146.4 CDJ49764.1 - 9.3e-19 67.7 0.2 1.1e-17 64.3 0.0 2.6 3 0 0 3 3 3 1 PIN domain of ribonuclease Ndc1_Nup PF09531.10 CDJ49764.1 - 3.4 6.2 6.8 4.1 6.0 6.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 CDJ49764.1 - 8.2 6.0 18.4 0.65 9.6 12.8 1.9 2 0 0 2 2 2 0 Spt20 family MoaE PF02391.17 CDJ49765.1 - 0.055 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 MoaE protein DUF4834 PF16118.5 CDJ49765.1 - 0.24 12.4 4.3 0.58 11.1 4.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Tau95_N PF17682.1 CDJ49765.1 - 0.76 10.0 7.9 0.3 11.3 5.1 1.7 2 0 0 2 2 2 0 Tau95 Triple barrel domain DUF5563 PF17718.1 CDJ49766.1 - 0.079 12.5 0.3 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5563) RNA_pol_Rpb2_1 PF04563.15 CDJ49768.1 - 1.7e-49 168.1 0.0 4.5e-49 166.7 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CDJ49768.1 - 1.7e-45 155.0 0.0 3.7e-45 153.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 CDJ49768.1 - 2e-26 92.0 0.0 4e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 CDJ49768.1 - 7.9e-21 74.1 0.1 1.8e-20 73.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 CDJ49768.1 - 8.2e-11 42.3 0.2 8.2e-11 42.3 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 TFIIA PF03153.13 CDJ49768.1 - 0.021 14.8 13.4 0.033 14.2 13.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF3_subunit PF08597.10 CDJ49768.1 - 0.025 14.5 4.8 0.039 13.9 4.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Presenilin PF01080.17 CDJ49768.1 - 0.099 11.4 3.4 0.14 10.9 3.4 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ49768.1 - 0.16 12.6 6.8 0.32 11.6 6.8 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.6 CDJ49768.1 - 0.22 11.2 4.6 0.43 10.2 4.6 1.4 1 0 0 1 1 1 0 FAM176 family SpoIIP PF07454.11 CDJ49768.1 - 0.23 10.9 5.2 0.36 10.2 5.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2722 PF10846.8 CDJ49768.1 - 0.37 9.7 15.4 0.58 9.0 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PPL5 PF18168.1 CDJ49768.1 - 1.1 8.5 4.3 2.3 7.5 4.3 1.4 1 0 0 1 1 1 0 Prim-pol family 5 EIIBC-GUT_N PF03612.14 CDJ49768.1 - 1.9 8.2 6.9 3.5 7.3 6.9 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Dynactin_p62 PF05502.13 CDJ49768.1 - 2.7 6.6 6.4 4.4 6.0 6.4 1.2 1 0 0 1 1 1 0 Dynactin p62 family eIF-3_zeta PF05091.12 CDJ49768.1 - 3.5 6.5 10.6 5.7 5.8 10.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RNase_PH PF01138.21 CDJ49769.1 - 1.1e-12 48.5 11.4 9.1e-12 45.6 11.4 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDJ49769.1 - 0.00022 21.2 0.0 0.00055 19.9 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SUIM_assoc PF16619.5 CDJ49769.1 - 0.0099 15.9 7.9 0.0099 15.9 7.9 3.4 3 1 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 Pox_G7 PF05503.12 CDJ49769.1 - 0.015 14.3 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus G7-like Dopey_N PF04118.14 CDJ49769.1 - 0.071 12.2 0.3 0.1 11.7 0.3 1.1 1 0 0 1 1 1 0 Dopey, N-terminal DUF2828 PF11443.8 CDJ49770.1 - 0.0015 16.7 7.4 0.0015 16.7 7.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2828) BUD22 PF09073.10 CDJ49770.1 - 0.029 13.7 31.8 0.024 14.0 13.1 2.3 2 0 0 2 2 2 0 BUD22 MDM10 PF12519.8 CDJ49771.1 - 0.00068 18.6 0.5 0.00068 18.6 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 SpoIIP PF07454.11 CDJ49771.1 - 0.0013 18.3 0.9 0.0014 18.2 0.9 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DUF3824 PF12868.7 CDJ49771.1 - 0.0023 18.6 11.5 0.0023 18.6 11.5 3.3 3 0 0 3 3 2 1 Domain of unknwon function (DUF3824) Glycoprotein_G PF00802.19 CDJ49771.1 - 0.0036 16.7 8.2 0.005 16.3 8.2 1.1 1 0 0 1 1 1 1 Pneumovirus attachment glycoprotein G Gti1_Pac2 PF09729.9 CDJ49771.1 - 0.0041 17.2 0.4 0.0041 17.2 0.4 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family Shadoo PF14999.6 CDJ49771.1 - 0.0041 17.2 0.4 0.0041 17.2 0.4 3.0 2 1 1 3 3 1 1 Shadow of prion protein, neuroprotective EPL1 PF10513.9 CDJ49771.1 - 0.0044 17.4 2.7 0.0048 17.3 2.7 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like Pex14_N PF04695.13 CDJ49771.1 - 0.007 17.0 21.6 0.013 16.1 21.5 1.6 1 1 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.17 CDJ49771.1 - 0.0079 16.4 3.1 0.0077 16.4 3.1 1.1 1 0 0 1 1 1 1 DDHD domain BAF1_ABF1 PF04684.13 CDJ49771.1 - 0.0088 15.2 6.4 0.013 14.6 6.4 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ49771.1 - 0.011 14.6 6.4 0.013 14.3 6.4 1.2 1 0 0 1 1 1 0 Presenilin CD20 PF04103.15 CDJ49771.1 - 0.019 15.1 0.1 0.019 15.1 0.1 1.9 2 0 0 2 2 2 0 CD20-like family OATP PF03137.20 CDJ49771.1 - 0.024 12.9 0.1 0.025 12.9 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Connexin PF00029.19 CDJ49771.1 - 0.06 13.1 4.6 0.08 12.7 4.6 1.1 1 0 0 1 1 1 0 Connexin Ctr PF04145.15 CDJ49771.1 - 0.089 13.4 2.1 0.12 13.0 2.1 1.3 1 0 0 1 1 1 0 Ctr copper transporter family DUF3464 PF11947.8 CDJ49771.1 - 0.09 12.5 5.8 0.16 11.7 5.8 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 HemX PF04375.14 CDJ49771.1 - 0.15 11.3 24.4 0.25 10.6 24.4 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase MPM1 PF17234.2 CDJ49771.1 - 0.15 12.3 12.8 0.21 11.8 12.8 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Nucleoside_tran PF01733.18 CDJ49771.1 - 0.18 11.2 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Nucleoside transporter CSG2 PF16965.5 CDJ49771.1 - 0.18 10.7 1.1 0.22 10.4 1.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator PAT1 PF09770.9 CDJ49771.1 - 0.25 9.5 18.2 0.29 9.3 18.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ49771.1 - 0.35 10.7 8.4 0.41 10.4 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 CDJ49771.1 - 0.36 11.0 5.8 0.58 10.3 5.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal EOS1 PF12326.8 CDJ49771.1 - 0.39 10.6 1.4 0.55 10.1 1.4 1.3 1 0 0 1 1 1 0 N-glycosylation protein Band_3_cyto PF07565.13 CDJ49771.1 - 0.58 9.9 8.7 0.75 9.5 8.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MMR1 PF08505.10 CDJ49771.1 - 0.77 10.0 11.8 1 9.6 11.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein 7tm_7 PF08395.12 CDJ49771.1 - 1.6 7.8 7.8 2.2 7.4 7.8 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor CLN3 PF02487.17 CDJ49771.1 - 1.7 7.6 6.4 2.8 6.9 6.4 1.3 1 0 0 1 1 1 0 CLN3 protein TERB2 PF15101.6 CDJ49771.1 - 2 8.5 13.6 2.6 8.0 13.6 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ALMT PF11744.8 CDJ49771.1 - 2.2 7.0 6.0 2.7 6.7 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4770 PF15994.5 CDJ49771.1 - 2.4 8.3 13.9 3.7 7.7 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Neur_chan_memb PF02932.16 CDJ49771.1 - 2.4 8.1 7.3 3.1 7.8 7.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EIIBC-GUT_N PF03612.14 CDJ49771.1 - 2.6 7.7 7.1 3.9 7.2 7.1 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus V_ATPase_I PF01496.19 CDJ49771.1 - 2.8 5.7 11.6 3.6 5.4 11.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4834 PF16118.5 CDJ49771.1 - 3.9 8.5 15.9 6.7 7.8 15.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ADP_PFK_GK PF04587.15 CDJ49771.1 - 4.9 5.6 14.4 0.013 14.1 3.1 1.9 2 0 0 2 2 2 0 ADP-specific Phosphofructokinase/Glucokinase conserved region DUF1980 PF09323.10 CDJ49771.1 - 6.7 6.6 10.5 2.6 7.9 8.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) EphA2_TM PF14575.6 CDJ49771.1 - 7.3 7.5 10.1 1.1e+02 3.8 10.1 2.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4231 PF14015.6 CDJ49771.1 - 8.4 6.9 9.3 14 6.2 2.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) eIF-3_zeta PF05091.12 CDJ49771.1 - 9.1 5.1 16.4 11 4.8 16.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) 60KD_IMP PF02096.20 CDJ49771.1 - 9.4 6.1 15.5 13 5.6 15.5 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein DUF2722 PF10846.8 CDJ49772.1 - 0.0094 14.9 0.8 0.0094 14.9 0.8 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) NST1 PF13945.6 CDJ49772.1 - 1.1 9.3 17.2 11 6.1 13.1 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator Neur_chan_memb PF02932.16 CDJ49772.1 - 2.2 8.3 6.2 5.3 7.0 1.0 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MAP65_ASE1 PF03999.12 CDJ49773.1 - 0.027 13.2 26.5 0.035 12.8 26.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Spt20 PF12090.8 CDJ49773.1 - 0.076 12.6 38.9 0.35 10.4 3.0 2.2 2 0 0 2 2 2 0 Spt20 family UPF0560 PF10577.9 CDJ49773.1 - 2.2 6.7 32.8 0.68 8.4 10.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 PAT1 PF09770.9 CDJ49773.1 - 3.1 5.9 25.0 3.6 5.7 25.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.19 CDJ49773.1 - 3.7 8.2 17.7 0.96 10.1 12.2 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein hDGE_amylase PF14701.6 CDJ49773.1 - 4.7 6.2 6.7 6.4 5.8 6.7 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF2681 PF10883.8 CDJ49773.1 - 5.9 7.4 24.7 9.5 6.7 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Rsc14 PF08586.10 CDJ49773.1 - 6.4 7.7 10.7 2.3 9.1 5.8 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DUF2722 PF10846.8 CDJ49774.1 - 0.00074 18.6 0.3 0.00074 18.6 0.3 4.6 4 2 1 5 5 5 2 Protein of unknown function (DUF2722) ATAD4 PF15321.6 CDJ49775.1 - 0.03 15.6 15.3 0.03 15.6 15.3 2.3 2 1 0 2 2 2 0 ATPase family AAA domain containing 4 CCSAP PF15748.5 CDJ49775.1 - 0.43 10.7 36.8 0.53 10.4 36.8 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PI3K_1B_p101 PF10486.9 CDJ49775.1 - 0.91 7.2 23.2 0.96 7.1 23.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit YL1 PF05764.13 CDJ49775.1 - 3.6 7.6 32.5 4.4 7.4 32.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Pex16 PF08610.10 CDJ49775.1 - 3.8 6.6 13.8 4.8 6.2 13.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) CDC27 PF09507.10 CDJ49775.1 - 3.8 6.8 27.8 4.5 6.5 27.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PNISR PF15996.5 CDJ49775.1 - 4.2 7.6 30.4 5.4 7.2 30.4 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR HSP70 PF00012.20 CDJ49775.1 - 7.6 4.6 14.7 8.3 4.5 14.7 1.0 1 0 0 1 1 1 0 Hsp70 protein Presenilin PF01080.17 CDJ49775.1 - 9.6 4.9 34.6 11 4.6 34.6 1.2 1 0 0 1 1 1 0 Presenilin Ribosomal_60s PF00428.19 CDJ49776.1 - 0.0032 18.0 3.1 0.0032 18.0 3.1 3.4 2 1 0 2 2 2 1 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ49776.1 - 0.0062 16.6 20.3 0.0082 16.2 20.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MDMPI_N PF11716.8 CDJ49776.1 - 0.06 14.0 17.5 0.061 14.0 0.6 2.3 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain PAT1 PF09770.9 CDJ49776.1 - 0.26 9.5 11.5 0.32 9.2 11.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4834 PF16118.5 CDJ49776.1 - 6.8 7.7 11.6 2.4 9.2 2.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) RskA PF10099.9 CDJ49776.1 - 7.8 6.8 35.5 0.068 13.5 17.4 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF4239 PF14023.6 CDJ49778.1 - 2.1 8.0 7.1 2.6 7.7 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) CDC45 PF02724.14 CDJ49779.1 - 0.59 8.4 20.5 0.62 8.3 20.5 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ49779.1 - 0.71 9.7 26.6 0.79 9.5 26.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ49779.1 - 0.98 8.1 31.0 1.1 8.0 31.0 1.0 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 CDJ49779.1 - 3.6 6.5 13.9 4.1 6.3 13.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 CDJ49779.1 - 4.4 6.2 25.4 4.7 6.1 25.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 CDJ49779.1 - 4.7 7.1 20.3 6.2 6.8 20.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A YABBY PF04690.13 CDJ49779.1 - 9.5 6.8 19.2 12 6.4 19.2 1.4 1 0 0 1 1 1 0 YABBY protein RskA PF10099.9 CDJ49780.1 - 0.00041 20.7 0.0 0.00041 20.7 0.0 23.3 11 6 5 17 17 17 5 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ49780.1 - 0.0025 17.9 12.6 0.0025 17.9 12.6 13.9 7 3 2 10 10 10 5 Transcription factor IIA, alpha/beta subunit rRNA_processing PF08524.11 CDJ49780.1 - 0.007 16.4 0.4 0.007 16.4 0.4 13.3 14 1 1 15 15 15 2 rRNA processing SR-25 PF10500.9 CDJ49780.1 - 0.018 14.7 0.3 0.018 14.7 0.3 19.2 18 3 2 20 20 20 0 Nuclear RNA-splicing-associated protein DUF2207 PF09972.9 CDJ49781.1 - 0.077 11.8 1.5 0.088 11.6 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 CDJ49781.1 - 0.14 13.0 0.8 29 5.6 0.0 2.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CDJ49781.1 - 9 6.2 0.0 9 6.2 0.0 5.4 4 2 1 5 5 5 0 TMEM154 protein family Ribosomal_60s PF00428.19 CDJ49782.1 - 0.14 12.7 10.5 0.55 10.9 10.5 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3824 PF12868.7 CDJ49782.1 - 0.47 11.1 10.7 0.66 10.6 7.5 2.4 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) SLC12 PF03522.15 CDJ49784.1 - 4.4 6.2 19.1 2.4 7.1 6.4 2.3 2 0 0 2 2 2 0 Solute carrier family 12 GREB1 PF15782.5 CDJ49785.1 - 0.015 12.5 28.4 0.019 12.1 28.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ49785.1 - 0.028 12.7 17.9 0.031 12.6 17.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.6 CDJ49785.1 - 0.3 9.4 4.6 0.44 8.9 4.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Dicty_REP PF05086.12 CDJ49785.1 - 1.1 7.2 15.5 1.4 6.8 15.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF936 PF06075.12 CDJ49785.1 - 2.6 6.8 29.7 3.4 6.5 29.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) RskA PF10099.9 CDJ49785.1 - 3.3 8.0 35.5 8.3 6.7 6.9 2.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Utp14 PF04615.13 CDJ49785.1 - 4.3 5.8 27.8 5.2 5.5 27.8 1.1 1 0 0 1 1 1 0 Utp14 protein Ribosomal_60s PF00428.19 CDJ49786.1 - 0.0018 18.8 3.9 0.0028 18.2 3.9 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein K_channel_TID PF07941.11 CDJ49786.1 - 0.031 14.7 13.6 0.042 14.3 13.6 1.1 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF2722 PF10846.8 CDJ49787.1 - 0.0017 17.4 8.4 0.0017 17.4 8.4 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) Gti1_Pac2 PF09729.9 CDJ49787.1 - 0.044 13.9 17.9 1.6 8.8 12.0 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family Otopetrin PF03189.13 CDJ49787.1 - 0.073 11.9 12.9 0.1 11.4 12.9 1.1 1 0 0 1 1 1 0 Otopetrin MAP7 PF05672.11 CDJ49787.1 - 0.41 10.3 37.3 0.18 11.5 20.0 2.1 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Peptidase_S64 PF08192.11 CDJ49787.1 - 0.42 9.0 16.0 0.52 8.7 16.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 CDJ49787.1 - 0.46 9.2 29.9 0.76 8.5 17.8 2.1 2 0 0 2 2 2 0 Presenilin eIF-3_zeta PF05091.12 CDJ49787.1 - 2.3 7.1 31.0 2.4 7.0 4.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIF4E-T PF10477.9 CDJ49787.1 - 2.8 6.7 37.6 3.6 6.3 37.6 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF572 PF04502.13 CDJ49787.1 - 3.5 7.1 22.4 1.2 8.7 9.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) TFIIA PF03153.13 CDJ49788.1 - 0.0018 18.4 27.4 0.0021 18.2 27.4 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TraT PF05818.12 CDJ49788.1 - 0.0036 17.0 15.5 0.0036 17.0 15.5 2.0 1 1 1 2 2 2 1 Enterobacterial TraT complement resistance protein Suf PF05843.14 CDJ49788.1 - 0.093 12.7 10.2 0.095 12.7 10.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF5585 PF17823.1 CDJ49788.1 - 0.12 11.3 25.0 0.13 11.1 25.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) MIIP PF15734.5 CDJ49788.1 - 0.29 10.6 6.9 0.32 10.5 6.9 1.1 1 0 0 1 1 1 0 Migration and invasion-inhibitory eIF-3_zeta PF05091.12 CDJ49788.1 - 0.46 9.4 12.7 0.56 9.1 12.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med15 PF09606.10 CDJ49788.1 - 0.9 8.1 30.6 1.2 7.7 30.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM60A PF15396.6 CDJ49788.1 - 1.6 8.7 4.9 2 8.4 4.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Activator_LAG-3 PF11498.8 CDJ49788.1 - 1.7 7.5 32.1 2.6 6.9 32.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ49788.1 - 1.8 8.1 28.3 2.4 7.7 28.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF726 PF05277.12 CDJ49788.1 - 2.1 7.2 8.4 2.2 7.1 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) RskA PF10099.9 CDJ49788.1 - 3.1 8.1 48.6 0.037 14.3 24.6 2.1 1 1 1 2 2 1 0 Anti-sigma-K factor rskA Mg_trans_NIPA PF05653.14 CDJ49791.1 - 6.5e-13 48.5 7.3 1.8e-07 30.6 0.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA SR-25 PF10500.9 CDJ49791.1 - 0.057 13.0 3.5 0.088 12.4 3.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ49792.1 - 0.0028 16.7 43.9 0.0052 15.8 23.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ49792.1 - 0.0068 16.7 13.2 0.0068 16.7 13.2 3.1 1 1 2 3 3 3 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ49792.1 - 0.008 15.8 59.1 0.035 13.7 32.0 2.1 2 0 0 2 2 2 2 Spt20 family DUF4834 PF16118.5 CDJ49792.1 - 0.01 16.8 22.2 0.05 14.6 9.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4064 PF13273.6 CDJ49792.1 - 0.069 13.4 2.7 0.35 11.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) PNISR PF15996.5 CDJ49792.1 - 0.11 12.8 24.1 0.12 12.6 11.8 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR RXT2_N PF08595.11 CDJ49792.1 - 0.18 11.8 9.0 0.34 10.9 2.0 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Gpi16 PF04113.14 CDJ49792.1 - 0.19 10.1 13.0 0.22 9.9 13.0 1.0 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component PAP2 PF01569.21 CDJ49792.1 - 0.24 11.1 5.9 26 4.6 5.9 2.3 1 1 0 1 1 1 0 PAP2 superfamily AAA_23 PF13476.6 CDJ49792.1 - 0.36 11.3 20.0 0.64 10.5 20.0 1.3 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 CDJ49792.1 - 0.49 9.4 19.4 0.63 9.0 19.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 ABC2_membrane_2 PF12679.7 CDJ49792.1 - 0.51 9.6 17.1 3.5 6.8 1.0 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein ATAD4 PF15321.6 CDJ49792.1 - 0.57 11.6 15.4 2.4 9.6 6.8 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DUF5327 PF17261.2 CDJ49792.1 - 0.68 10.7 28.9 0.079 13.7 10.6 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF4820 PF16091.5 CDJ49792.1 - 0.71 9.2 17.7 0.82 9.0 7.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF719 PF05334.13 CDJ49792.1 - 0.72 10.0 18.4 0.2 11.8 7.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Pet20 PF08692.10 CDJ49792.1 - 0.82 10.4 7.4 0.83 10.4 1.2 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 SAPS PF04499.15 CDJ49792.1 - 0.89 8.3 12.6 1.2 7.9 12.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ARF7EP_C PF14949.6 CDJ49792.1 - 1.8 9.2 16.6 5.6 7.6 1.1 2.3 2 0 0 2 2 2 0 ARF7 effector protein C-terminus Med15 PF09606.10 CDJ49792.1 - 1.9 7.1 59.6 3.1 6.4 59.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Afaf PF15339.6 CDJ49792.1 - 2 8.1 8.0 0.066 12.9 1.3 1.7 2 0 0 2 2 2 0 Acrosome formation-associated factor Afi1 PF07792.12 CDJ49792.1 - 2.2 8.7 16.5 2.5 8.6 7.9 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3464 PF11947.8 CDJ49792.1 - 2.3 8.0 21.8 1.8 8.3 10.6 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF1764 PF08576.10 CDJ49792.1 - 2.3 9.2 19.2 5 8.1 10.4 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) AIF_C PF14721.6 CDJ49792.1 - 2.3 8.6 18.6 0.72 10.2 7.3 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3408 PF11888.8 CDJ49792.1 - 2.3 8.4 21.6 2.6 8.2 11.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) MMU163 PF17119.5 CDJ49792.1 - 2.5 7.2 12.7 0.2 10.8 4.2 2.0 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Pex14_N PF04695.13 CDJ49792.1 - 2.8 8.6 46.1 0.13 12.9 22.1 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S49_N PF08496.10 CDJ49792.1 - 3.4 7.7 16.5 0.59 10.2 6.1 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Slu7 PF11708.8 CDJ49792.1 - 4.7 6.9 24.2 0.98 9.1 12.8 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor Peroxin-13_N PF04088.13 CDJ49792.1 - 4.7 7.5 14.1 1.1 9.6 4.6 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region G0-G1_switch_2 PF15103.6 CDJ49792.1 - 5.2 7.6 18.1 1.1 9.8 7.2 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 LMBR1 PF04791.16 CDJ49792.1 - 5.5 5.8 12.8 7.4 5.4 12.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DDRGK PF09756.9 CDJ49792.1 - 6.3 6.4 27.4 1.3 8.5 14.8 2.1 2 0 0 2 2 2 0 DDRGK domain PRC2_HTH_1 PF18118.1 CDJ49792.1 - 7 7.5 16.1 4.1 8.3 6.9 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Trp_oprn_chp PF09534.10 CDJ49792.1 - 7.3 6.3 30.9 4.3 7.1 12.0 2.2 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MPM1 PF17234.2 CDJ49792.1 - 8.7 6.6 23.7 1.3 9.3 10.6 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 PTPRCAP PF15713.5 CDJ49793.1 - 0.01 16.1 16.3 0.01 16.1 16.3 2.5 2 1 1 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated Peptidase_S64 PF08192.11 CDJ49793.1 - 0.064 11.7 27.3 0.089 11.3 27.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Tmemb_cc2 PF10267.9 CDJ49793.1 - 3.9 6.5 32.6 5.4 6.1 32.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF4799 PF16056.5 CDJ49796.1 - 0.0031 16.7 1.4 0.0033 16.6 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4799) DUF4813 PF16072.5 CDJ49796.1 - 1.7 8.2 25.0 2.2 7.9 25.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Apt1 PF10351.9 CDJ49797.1 - 0.25 10.1 16.1 0.24 10.2 16.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 CDJ49797.1 - 0.29 8.2 17.4 0.26 8.4 17.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PPP4R2 PF09184.11 CDJ49797.1 - 1.1 8.8 11.3 1.1 8.8 11.3 1.1 1 0 0 1 1 1 0 PPP4R2 PI3K_1B_p101 PF10486.9 CDJ49797.1 - 1.2 6.8 10.9 1.2 6.8 10.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Lin-8 PF03353.15 CDJ49797.1 - 1.6 8.3 13.7 2.5 7.6 13.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Peptidase_S64 PF08192.11 CDJ49797.1 - 1.6 7.1 20.0 1.7 7.0 20.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 SLC12 PF03522.15 CDJ49797.1 - 3.7 6.4 7.3 4.1 6.3 7.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 CDJ49797.1 - 4 6.3 5.8 3.8 6.3 5.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Rrn6 PF10214.9 CDJ49797.1 - 6.5 5.1 21.0 8.2 4.8 21.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MCM_bind PF09739.9 CDJ49797.1 - 7.1 5.0 9.5 9.1 4.6 9.5 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PRP38 PF03371.15 CDJ49798.1 - 2.9e-05 24.0 0.0 5.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 PRP38 family DUF1345 PF07077.11 CDJ49799.1 - 0.091 12.5 6.4 0.2 11.3 5.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) Filament_head PF04732.14 CDJ49799.1 - 0.65 10.9 8.7 0.83 10.6 7.6 1.7 1 1 0 1 1 1 0 Intermediate filament head (DNA binding) region TFIIA PF03153.13 CDJ49800.1 - 0.043 13.8 21.1 0.057 13.4 21.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 CDJ49801.1 - 0.046 12.1 10.0 0.057 11.8 10.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAGA-Tad1 PF12767.7 CDJ49801.1 - 0.28 10.9 27.3 0.3 10.8 27.3 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FAM60A PF15396.6 CDJ49801.1 - 0.44 10.5 24.3 0.53 10.3 24.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF572 PF04502.13 CDJ49801.1 - 0.63 9.6 26.4 0.82 9.2 26.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ALMT PF11744.8 CDJ49801.1 - 0.72 8.6 24.2 0.75 8.6 24.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CDC45 PF02724.14 CDJ49801.1 - 0.79 7.9 26.9 0.89 7.8 26.9 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ49801.1 - 1.1 9.1 34.2 1.4 8.6 34.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Shadoo PF14999.6 CDJ49801.1 - 1.1 9.4 14.0 1.7 8.8 14.0 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective MAJIN PF15077.6 CDJ49801.1 - 1.1 8.9 22.9 1.6 8.5 22.9 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein RIFIN PF02009.16 CDJ49801.1 - 1.2 9.0 27.6 1.5 8.7 27.6 1.0 1 0 0 1 1 1 0 Rifin Neur_chan_memb PF02932.16 CDJ49801.1 - 1.3 9.0 24.2 1.5 8.8 24.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.13 CDJ49801.1 - 2 7.3 21.2 2.4 7.0 21.2 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hamartin PF04388.12 CDJ49801.1 - 2.7 6.6 28.4 2.9 6.4 28.4 1.0 1 0 0 1 1 1 0 Hamartin protein AAA_11 PF13086.6 CDJ49801.1 - 2.9 7.6 29.5 3.7 7.3 29.5 1.2 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 CDJ49801.1 - 3.3 6.6 33.1 3.6 6.5 33.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 CDJ49801.1 - 4.7 5.2 29.3 5 5.1 29.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pap_E4 PF02711.14 CDJ49803.1 - 0.22 12.5 17.0 0.2 12.7 6.6 2.1 2 0 0 2 2 2 0 E4 protein Mitofilin PF09731.9 CDJ49803.1 - 2.3 6.9 21.7 2.9 6.6 21.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Serinc PF03348.15 CDJ49803.1 - 2.8 6.7 4.9 3.5 6.4 4.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CDC27 PF09507.10 CDJ49803.1 - 3.1 7.1 23.1 3.8 6.8 23.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Peroxin-3 PF04882.12 CDJ49803.1 - 3.2 6.6 14.5 4.9 6.0 14.5 1.2 1 0 0 1 1 1 0 Peroxin-3 SLC12 PF03522.15 CDJ49803.1 - 4 6.3 6.4 5.4 5.9 6.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CHDCT2 PF08074.11 CDJ49803.1 - 5 7.3 9.0 0.43 10.7 0.6 2.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Hamartin PF04388.12 CDJ49803.1 - 5.5 5.5 19.4 6.4 5.3 19.4 1.0 1 0 0 1 1 1 0 Hamartin protein SPX PF03105.19 CDJ49803.1 - 5.5 6.8 15.1 7 6.5 15.1 1.1 1 0 0 1 1 1 0 SPX domain Herpes_BLLF1 PF05109.13 CDJ49803.1 - 5.8 4.8 20.0 6.8 4.5 20.0 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Retinal PF15449.6 CDJ49803.1 - 6.6 4.4 30.2 7.9 4.1 30.2 1.0 1 0 0 1 1 1 0 Retinal protein BAF1_ABF1 PF04684.13 CDJ49803.1 - 9.5 5.1 14.1 14 4.6 14.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4407 PF14362.6 CDJ49804.1 - 5.6e-06 25.9 8.6 0.0002 20.8 0.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) DUF2828 PF11443.8 CDJ49804.1 - 0.00042 18.5 4.3 0.079 11.0 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF2828) MecA PF05389.12 CDJ49804.1 - 0.0006 19.5 7.2 0.02 14.5 0.1 2.2 2 0 0 2 2 2 2 Negative regulator of genetic competence (MecA) RskA PF10099.9 CDJ49804.1 - 0.0034 17.7 7.7 0.01 16.2 0.0 2.2 1 1 0 2 2 2 1 Anti-sigma-K factor rskA Connexin PF00029.19 CDJ49804.1 - 0.0043 16.8 8.2 0.019 14.7 0.5 2.3 2 0 0 2 2 2 1 Connexin TFIIA PF03153.13 CDJ49804.1 - 0.016 15.2 48.3 0.074 13.0 13.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CAF1 PF04857.20 CDJ49804.1 - 0.024 13.8 5.3 0.05 12.8 5.3 1.5 1 1 0 1 1 1 0 CAF1 family ribonuclease MAT1 PF06391.13 CDJ49804.1 - 0.055 13.3 24.8 0.47 10.3 4.4 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 V_ATPase_I PF01496.19 CDJ49804.1 - 0.066 11.1 11.4 0.22 9.4 3.6 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Med15 PF09606.10 CDJ49804.1 - 0.085 11.5 43.3 0.2 10.3 9.9 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal SpoIIP PF07454.11 CDJ49804.1 - 0.15 11.5 15.1 0.37 10.2 3.6 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF3347 PF11827.8 CDJ49804.1 - 0.15 12.2 14.2 0.08 13.1 1.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3347) DUF4770 PF15994.5 CDJ49804.1 - 0.16 12.2 18.1 0.74 10.0 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) FHIPEP PF00771.20 CDJ49804.1 - 0.17 10.3 11.4 0.048 12.1 0.8 2.1 2 0 0 2 2 2 0 FHIPEP family EIIBC-GUT_N PF03612.14 CDJ49804.1 - 0.23 11.2 17.9 1.4 8.7 3.0 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus RLL PF10036.9 CDJ49804.1 - 0.24 11.2 15.3 1.4 8.7 6.3 2.2 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein DUF4518 PF15008.6 CDJ49804.1 - 0.56 9.3 17.7 0.81 8.8 7.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) Orf78 PF06024.12 CDJ49804.1 - 0.59 10.5 12.1 0.25 11.7 1.2 2.6 3 0 0 3 3 2 0 Orf78 (ac78) Rsc14 PF08586.10 CDJ49804.1 - 0.65 10.8 7.8 5.8 7.8 1.0 2.4 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Folate_carrier PF01770.18 CDJ49804.1 - 0.71 8.5 8.1 0.59 8.8 0.5 2.2 2 0 0 2 2 2 0 Reduced folate carrier Renin_r PF07850.14 CDJ49804.1 - 0.77 10.4 5.8 1.9 9.1 0.4 2.4 2 0 0 2 2 2 0 Renin receptor-like protein DUF5385 PF17359.2 CDJ49804.1 - 0.8 9.2 18.7 0.3 10.6 3.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) MotA_ExbB PF01618.16 CDJ49804.1 - 1 9.1 7.1 0.13 12.1 0.4 2.1 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family DUF2397 PF09660.10 CDJ49804.1 - 1.3 7.8 13.0 0.97 8.3 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) DUF3915 PF13054.6 CDJ49804.1 - 1.5 8.8 4.6 1.9 8.5 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Spore_coat_CotO PF14153.6 CDJ49804.1 - 1.6 8.6 24.6 0.091 12.7 3.0 2.3 2 0 0 2 2 2 0 Spore coat protein CotO RPA43_OB PF17875.1 CDJ49804.1 - 1.7 9.2 16.4 3.1 8.4 2.4 3.0 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Rrp15p PF07890.12 CDJ49804.1 - 2 8.7 19.3 1.8 8.9 4.5 2.2 2 0 0 2 2 2 0 Rrp15p MCD PF05292.11 CDJ49804.1 - 2.2 7.8 9.5 4.9 6.6 1.2 2.1 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain Macoilin PF09726.9 CDJ49804.1 - 2.4 6.6 36.3 5.7 5.4 36.3 1.5 1 1 0 1 1 1 0 Macoilin family PH_4 PF15404.6 CDJ49804.1 - 2.5 7.9 13.4 3.7 7.3 4.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Peroxin-13_N PF04088.13 CDJ49804.1 - 2.9 8.1 11.0 0.53 10.5 0.3 2.6 3 0 0 3 3 2 0 Peroxin 13, N-terminal region tRNA-synt_1_2 PF13603.6 CDJ49804.1 - 3.2 7.2 6.7 2.4 7.6 0.7 2.2 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 DUF2203 PF09969.9 CDJ49804.1 - 3.4 8.4 14.0 1.6 9.5 1.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Tim54 PF11711.8 CDJ49804.1 - 3.4 6.4 12.9 2.4 6.8 1.5 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RICTOR_N PF14664.6 CDJ49804.1 - 3.9 6.3 12.4 0.26 10.2 3.8 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term DUF2371 PF10177.9 CDJ49804.1 - 4.1 7.6 5.1 13 6.0 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF1644 PF07800.12 CDJ49804.1 - 4.2 7.4 19.6 2.4 8.2 4.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) Glt_symporter PF03616.14 CDJ49804.1 - 4.9 5.7 10.0 0.56 8.8 2.1 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter DUF2126 PF09899.9 CDJ49804.1 - 4.9 5.1 8.3 1.2 7.1 0.4 2.0 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) Mak16 PF04874.14 CDJ49804.1 - 5 7.8 12.0 13 6.5 3.0 2.3 2 0 0 2 2 2 0 Mak16 protein C-terminal region CDT1_C PF16679.5 CDJ49804.1 - 5 7.6 17.3 5.3 7.5 3.0 2.9 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain MTP18 PF10558.9 CDJ49804.1 - 5.4 6.9 8.1 4.7 7.1 1.1 2.2 2 0 0 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) DUF4064 PF13273.6 CDJ49804.1 - 6.1 7.2 5.2 8.8 6.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2254 PF10011.9 CDJ49804.1 - 6.1 5.6 10.2 2.3 6.9 1.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) MMR1 PF08505.10 CDJ49804.1 - 6.1 7.0 32.0 8.3 6.6 14.1 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Rad54_N PF08658.10 CDJ49804.1 - 6.5 6.9 14.0 5.9 7.0 4.2 2.3 2 0 0 2 2 2 0 Rad54 N terminal WBP-1 PF11669.8 CDJ49804.1 - 6.8 7.4 16.8 2.8 8.6 7.6 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 SLC12 PF03522.15 CDJ49804.1 - 7 5.6 19.6 5.2 6.0 5.6 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Thg1C PF14413.6 CDJ49804.1 - 7.2 6.8 16.6 5.7 7.1 5.4 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain DUF1115 PF06544.12 CDJ49804.1 - 7.2 6.7 13.9 1.9 8.6 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) DUF3408 PF11888.8 CDJ49804.1 - 8.1 6.6 21.0 10 6.2 6.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF3464 PF11947.8 CDJ49804.1 - 9.3 6.0 19.9 8.1 6.2 6.6 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Pet20 PF08692.10 CDJ49804.1 - 9.8 6.9 11.0 8.1 7.2 0.6 2.4 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Presenilin PF01080.17 CDJ49805.1 - 0.0097 14.7 26.0 0.013 14.3 26.0 1.3 1 0 0 1 1 1 1 Presenilin CDC45 PF02724.14 CDJ49805.1 - 0.059 11.7 16.7 0.069 11.4 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ49805.1 - 0.27 11.0 24.7 0.4 10.5 24.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOBP PF15279.6 CDJ49805.1 - 0.58 10.7 26.9 0.89 10.1 26.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PA26 PF04636.13 CDJ49805.1 - 0.66 8.8 16.6 0.97 8.3 16.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Mitofilin PF09731.9 CDJ49805.1 - 0.75 8.6 36.6 0.97 8.2 36.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Asp-B-Hydro_N PF05279.11 CDJ49805.1 - 1 9.4 18.6 1.3 9.0 18.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MDM10 PF12519.8 CDJ49805.1 - 1.2 7.9 16.7 1.6 7.5 16.7 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Med15 PF09606.10 CDJ49805.1 - 1.7 7.2 60.8 2.3 6.8 60.8 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDK5_activator PF03261.15 CDJ49805.1 - 1.9 7.9 19.2 2.3 7.7 19.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SID-1_RNA_chan PF13965.6 CDJ49805.1 - 5.3 5.3 7.4 6.3 5.1 7.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 CDJ49805.1 - 5.3 5.9 26.0 7.1 5.5 26.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 CDJ49805.1 - 6.7 5.4 26.4 11 4.7 26.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ALMT PF11744.8 CDJ49805.1 - 6.8 5.4 18.7 9.2 5.0 18.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4746 PF15928.5 CDJ49805.1 - 7 6.0 20.5 10 5.4 20.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PAT1 PF09770.9 CDJ49805.1 - 7.3 4.7 48.4 9.5 4.3 48.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Paramyxo_ncap PF00973.19 CDJ49805.1 - 9 5.1 19.2 11 4.7 19.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SAPS PF04499.15 CDJ49805.1 - 9.6 4.9 18.5 12 4.5 18.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pol_alpha_B_N PF08418.10 CDJ49806.1 - 0.033 14.1 8.3 0.04 13.9 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal GREB1 PF15782.5 CDJ49806.1 - 0.28 8.3 0.9 0.33 8.0 0.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Focal_AT PF03623.13 CDJ49807.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Focal adhesion targeting region SUIM_assoc PF16619.5 CDJ49808.1 - 0.00053 20.0 13.7 0.067 13.3 4.1 3.3 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ49808.1 - 0.29 11.1 24.9 0.42 10.6 24.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ49808.1 - 0.68 8.4 10.3 0.92 8.0 10.3 1.3 1 0 0 1 1 1 0 Macoilin family Spt20 PF12090.8 CDJ49808.1 - 2.1 7.9 25.3 3.1 7.3 5.2 2.2 2 0 0 2 2 2 0 Spt20 family HemY_N PF07219.13 CDJ49808.1 - 2.9 8.1 13.4 3.8 7.7 2.5 2.8 2 0 0 2 2 2 0 HemY protein N-terminus OmpH PF03938.14 CDJ49808.1 - 3.4 8.0 17.2 7.5 6.9 7.7 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FliD_N PF02465.18 CDJ49808.1 - 4 8.2 21.5 3.3 8.5 4.2 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Histone_HNS PF00816.21 CDJ49808.1 - 7.5 7.5 11.1 7.5 7.5 0.6 2.5 2 0 0 2 2 2 0 H-NS histone family Activator_LAG-3 PF11498.8 CDJ49809.1 - 0.0019 17.2 42.4 0.0019 17.2 42.4 3.0 3 0 0 3 3 3 1 Transcriptional activator LAG-3 tRNA-synt_1g PF09334.11 CDJ49809.1 - 0.11 11.2 0.0 0.52 9.0 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (M) DFRP_C PF16543.5 CDJ49809.1 - 0.4 11.2 6.7 0.42 11.1 0.3 2.7 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 CDH1_2_SANT_HL1 PF18375.1 CDJ49809.1 - 0.42 11.3 3.9 5.5 7.7 0.2 2.7 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Rgp1 PF08737.10 CDJ49809.1 - 2 7.5 12.8 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Rgp1 IP_trans PF02121.18 CDJ49810.1 - 0.14 11.7 0.2 0.19 11.2 0.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein VIR_N PF15912.5 CDJ49810.1 - 0.31 10.6 5.2 0.61 9.6 5.2 1.4 1 1 0 1 1 1 0 Virilizer, N-terminal TFIIA PF03153.13 CDJ49810.1 - 1.2 9.1 8.7 1.6 8.6 8.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ49810.1 - 5.2 6.6 11.4 7 6.2 11.4 1.1 1 0 0 1 1 1 0 Spt20 family BUD22 PF09073.10 CDJ49811.1 - 0.0021 17.5 28.0 0.0027 17.1 28.0 1.1 1 0 0 1 1 1 1 BUD22 K_channel_TID PF07941.11 CDJ49811.1 - 0.01 16.3 13.0 0.01 16.3 13.0 5.2 3 2 1 4 4 2 0 Potassium channel Kv1.4 tandem inactivation domain Utp14 PF04615.13 CDJ49811.1 - 0.012 14.3 32.3 0.013 14.1 32.3 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 CDJ49811.1 - 0.085 11.4 36.6 0.12 10.9 36.6 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CDJ49811.1 - 0.12 9.4 37.5 0.16 9.1 37.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Caldesmon PF02029.15 CDJ49811.1 - 0.23 10.2 31.0 0.3 9.8 31.0 1.1 1 0 0 1 1 1 0 Caldesmon MMR1 PF08505.10 CDJ49811.1 - 0.35 11.1 41.4 0.52 10.6 41.4 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PAP1 PF08601.10 CDJ49811.1 - 1.8 8.2 44.2 2.3 7.8 44.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 PIEZO PF15917.5 CDJ49811.1 - 2.2 7.7 31.5 3.5 7.0 31.5 1.3 1 0 0 1 1 1 0 Piezo Peptidase_S64 PF08192.11 CDJ49811.1 - 6 5.2 37.4 7.6 4.9 37.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Draxin PF15550.6 CDJ49811.1 - 6 6.6 27.1 8.5 6.1 27.1 1.3 1 0 0 1 1 1 0 Draxin Peptidase_S8 PF00082.22 CDJ49812.1 - 8.7e-05 21.9 3.5 8.7e-05 21.9 3.5 2.8 2 1 0 2 2 2 1 Subtilase family TFIIA PF03153.13 CDJ49812.1 - 0.0087 16.1 5.7 0.01 15.8 5.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cu-binding_MopE PF11617.8 CDJ49812.1 - 0.033 14.3 2.1 0.072 13.3 2.1 1.6 1 0 0 1 1 1 0 Putative metal-binding motif CHD5 PF04420.14 CDJ49812.1 - 0.29 11.0 2.8 0.45 10.4 2.8 1.3 1 0 0 1 1 1 0 CHD5-like protein Macoilin PF09726.9 CDJ49812.1 - 0.31 9.6 3.1 0.38 9.3 3.1 1.0 1 0 0 1 1 1 0 Macoilin family Spt20 PF12090.8 CDJ49812.1 - 0.87 9.2 15.0 1.3 8.6 15.0 1.2 1 0 0 1 1 1 0 Spt20 family CDC14 PF08045.11 CDJ49812.1 - 0.96 8.5 0.0 0.96 8.5 0.0 2.0 1 1 1 2 2 2 0 Cell division control protein 14, SIN component DUF4834 PF16118.5 CDJ49812.1 - 4.4 8.3 5.9 2.6 9.1 3.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ49814.1 - 0.0033 16.5 7.2 0.0033 16.5 7.2 13.5 8 5 4 12 12 12 1 Protein of unknown function (DUF2722) HECT PF00632.25 CDJ49815.1 - 2.9e-31 109.1 0.0 3.1e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RskA PF10099.9 CDJ49816.1 - 0.025 14.9 31.1 0.048 14.0 30.5 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SID-1_RNA_chan PF13965.6 CDJ49816.1 - 0.19 10.1 8.2 0.22 9.9 8.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Bac_luciferase PF00296.20 CDJ49816.1 - 0.31 10.4 15.4 0.39 10.1 15.4 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Caldesmon PF02029.15 CDJ49816.1 - 0.78 8.4 27.7 0.91 8.2 27.7 1.1 1 0 0 1 1 1 0 Caldesmon BAF1_ABF1 PF04684.13 CDJ49816.1 - 1.3 8.0 31.2 1.7 7.6 31.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ49816.1 - 1.6 7.4 30.1 2.7 6.7 30.1 1.3 1 0 0 1 1 1 0 Presenilin PBP1_TM PF14812.6 CDJ49816.1 - 1.8 9.0 9.7 8.7 6.8 4.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM199X PF15814.5 CDJ49816.1 - 3.1 6.8 14.0 3.5 6.6 14.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X Serinc PF03348.15 CDJ49816.1 - 3.4 6.5 12.8 4.6 6.1 12.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF5134 PF17197.4 CDJ49816.1 - 3.7 7.4 15.5 4.6 7.1 15.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) DUF5523 PF17661.1 CDJ49816.1 - 5.3 6.6 28.3 6.7 6.3 28.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Peptidase_S49_N PF08496.10 CDJ49816.1 - 7.2 6.7 25.0 1.9 8.5 15.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal UBA PF00627.31 CDJ49817.1 - 1.7e-08 34.2 0.6 6.4e-08 32.4 0.6 2.1 1 0 0 1 1 1 1 UBA/TS-N domain BUD22 PF09073.10 CDJ49817.1 - 3.7e-06 26.6 18.6 0.0014 18.1 19.2 21.6 16 9 2 19 19 19 5 BUD22 Caldesmon PF02029.15 CDJ49817.1 - 0.00075 18.4 14.8 0.00075 18.4 14.8 13.6 10 4 1 11 11 11 3 Caldesmon DUF4834 PF16118.5 CDJ49817.1 - 0.006 17.5 0.0 0.006 17.5 0.0 32.9 22 10 3 25 25 25 1 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ49818.1 - 0.0065 16.1 12.7 0.0065 16.1 12.7 3.4 3 0 0 3 3 3 2 Spt20 family HyaE PF07449.11 CDJ49818.1 - 0.044 13.8 0.1 0.62 10.1 0.0 2.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Pex24p PF06398.11 CDJ49818.1 - 0.22 10.5 0.0 0.22 10.5 0.0 1.6 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Plasmodium_Vir PF05795.11 CDJ49818.1 - 0.55 9.6 5.0 1.1 8.6 5.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RAP1 PF07218.11 CDJ49818.1 - 2.4 6.3 9.3 3.1 6.0 9.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF966 PF06136.13 CDJ49819.1 - 0.24 11.1 23.6 0.31 10.7 23.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SR-25 PF10500.9 CDJ49819.1 - 0.38 10.3 33.6 1.2 8.7 17.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HpaB_N PF11794.8 CDJ49819.1 - 6.3 6.4 7.9 11 5.6 7.9 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Neur_chan_memb PF02932.16 CDJ49819.1 - 7.6 6.5 26.2 25 4.8 26.2 1.7 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Integrase_H2C2 PF17921.1 CDJ49820.1 - 6e-17 61.5 1.3 6e-17 61.5 1.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CDJ49820.1 - 1.1e-15 57.9 0.0 2.6e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 CDJ49820.1 - 3.4e-15 56.2 0.4 8e-15 55.0 0.4 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ49820.1 - 1.8e-05 24.7 0.0 3.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CDJ49820.1 - 0.00015 21.9 0.6 0.00036 20.7 0.6 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDJ49820.1 - 0.0002 21.0 0.2 0.029 14.1 0.1 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_3 PF13456.6 CDJ49820.1 - 0.0076 16.1 0.0 0.021 14.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase-like CUE PF02845.16 CDJ49821.1 - 0.0034 17.1 0.0 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 CUE domain DUF4110 PF13422.6 CDJ49822.1 - 3.6e-18 65.4 0.7 3.6e-18 65.4 0.7 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 CDJ49822.1 - 9.7e-18 63.9 0.1 2.9e-10 40.0 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ49822.1 - 2.6e-08 33.9 0.1 0.021 15.1 0.0 3.4 2 1 1 3 3 3 3 Kelch motif Kelch_3 PF13415.6 CDJ49822.1 - 2.8e-08 33.8 0.1 9e-06 25.8 0.0 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ49822.1 - 0.00022 21.1 0.1 6.1 6.9 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CDJ49822.1 - 0.033 14.2 0.7 0.73 9.9 0.0 3.1 3 0 0 3 3 3 0 Kelch motif DUF3103 PF11301.8 CDJ49822.1 - 0.19 10.5 0.0 0.48 9.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) Histone PF00125.24 CDJ49822.1 - 1.6 9.1 12.8 3.9 7.8 3.9 2.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Ribosomal_S3Ae PF01015.18 CDJ49823.1 - 3.1e-89 297.9 0.2 3.8e-89 297.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Kelch_4 PF13418.6 CDJ49824.1 - 6.5e-14 51.7 3.3 1.2e-05 25.2 0.0 5.4 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ49824.1 - 3.4e-13 49.5 0.4 2.8e-07 30.7 0.1 4.4 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ49824.1 - 7.9e-13 48.1 2.0 0.0024 17.8 0.0 5.5 5 0 0 5 5 5 3 Kelch motif HATPase_c_3 PF13589.6 CDJ49824.1 - 1.4e-08 34.6 0.0 2.7e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ49824.1 - 0.00037 21.0 0.0 0.00075 20.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_6 PF13964.6 CDJ49824.1 - 0.00089 19.5 2.7 0.19 12.1 0.1 4.2 2 2 3 5 5 5 1 Kelch motif Kelch_1 PF01344.25 CDJ49824.1 - 0.0027 17.2 0.1 1.5 8.5 0.0 2.9 2 0 0 2 2 2 2 Kelch motif PDCD2_C PF04194.13 CDJ49825.1 - 2.3e-34 119.0 1.5 1.2e-31 110.1 0.0 2.7 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain WHH PF14414.6 CDJ49825.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH vATP-synt_E PF01991.18 CDJ49826.1 - 1e-59 201.3 1.0 1.3e-59 201.0 1.0 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4239 PF14023.6 CDJ49826.1 - 0.0043 16.8 4.5 0.051 13.3 4.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4239) IL13 PF03487.13 CDJ49826.1 - 0.054 13.3 1.7 0.11 12.2 0.4 2.0 2 0 0 2 2 2 0 Interleukin-13 Helicase_PWI PF18149.1 CDJ49826.1 - 0.064 13.4 5.0 0.047 13.9 3.0 1.8 2 0 0 2 2 2 0 N-terminal helicase PWI domain CemA PF03040.14 CDJ49826.1 - 0.49 10.3 4.6 0.71 9.8 4.6 1.3 1 0 0 1 1 1 0 CemA family Dynein_light PF01221.18 CDJ49826.1 - 4.1 7.8 5.7 4.1 7.8 3.5 2.1 2 0 0 2 2 2 0 Dynein light chain type 1 Lipase_3 PF01764.25 CDJ49827.1 - 7.1e-17 61.6 0.0 1.2e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CDJ49827.1 - 0.00039 19.8 0.0 0.00074 18.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ49827.1 - 0.0026 18.4 4.7 0.0026 18.4 4.7 2.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.22 CDJ49827.1 - 0.027 14.5 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.20 CDJ49827.1 - 0.089 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CDJ49827.1 - 0.11 12.4 0.9 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 CDJ49827.1 - 0.25 10.8 0.1 0.65 9.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Phage_antiter_Q PF06323.11 CDJ49828.1 - 0.098 12.2 0.1 0.28 10.7 0.1 1.7 1 0 0 1 1 1 0 Phage antitermination protein Q MA3 PF02847.17 CDJ49829.1 - 2.3e-30 104.8 1.4 6.9e-10 38.9 0.0 3.2 3 0 0 3 3 3 3 MA3 domain PARP PF00644.20 CDJ49830.1 - 1.1e-10 41.5 0.0 1.7e-05 24.5 0.0 2.6 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain Pex16 PF08610.10 CDJ49831.1 - 2.2e-28 99.4 2.5 7.8e-17 61.4 0.1 2.7 2 1 1 3 3 3 2 Peroxisomal membrane protein (Pex16) Sec7 PF01369.20 CDJ49832.1 - 1.3e-65 220.6 0.0 1.9e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CDJ49832.1 - 4.7e-13 49.3 0.1 2.1e-12 47.2 0.1 2.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal ASH PF15780.5 CDJ49833.1 - 2.4e-06 27.7 1.8 0.63 10.3 0.1 5.8 8 0 0 8 8 8 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CDJ49833.1 - 1.8e-05 24.9 0.1 0.0046 17.1 0.0 3.4 3 0 0 3 3 3 1 Flagellar-associated PapD-like PAZ PF02170.22 CDJ49834.1 - 1.6e-09 37.7 0.0 6.7e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 PAZ domain Herpes_PAP PF03325.13 CDJ49834.1 - 0.036 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein WGG PF10273.9 CDJ49836.1 - 2e-23 82.8 0.4 2e-23 82.8 0.4 1.8 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 SUIM_assoc PF16619.5 CDJ49836.1 - 6.9e-06 26.0 13.5 0.081 13.0 1.6 3.5 3 1 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 RRP7 PF12923.7 CDJ49836.1 - 0.0014 18.8 0.0 0.0014 18.8 0.0 2.2 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RskA PF10099.9 CDJ49836.1 - 0.29 11.4 15.7 0.032 14.5 7.7 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF3824 PF12868.7 CDJ49836.1 - 2.1 9.0 8.1 0.7 10.5 4.5 2.0 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) AAA_12 PF13087.6 CDJ49837.1 - 3.7e-31 108.3 0.0 9.4e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ49837.1 - 5.6e-13 49.3 0.0 5.6e-13 49.3 0.0 4.9 3 2 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CDJ49837.1 - 7.7e-07 29.5 0.0 7e-06 26.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF2439 PF10382.9 CDJ49837.1 - 2.2e-05 24.7 0.0 0.0001 22.5 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Viral_helicase1 PF01443.18 CDJ49837.1 - 4.7e-05 23.2 4.0 1.1 9.0 0.0 4.3 4 1 0 4 4 4 3 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 CDJ49837.1 - 0.22 11.5 0.1 0.42 10.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UvrD_C_2 PF13538.6 CDJ49837.1 - 0.26 11.1 4.7 4.9 7.1 0.2 2.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Caldesmon PF02029.15 CDJ49839.1 - 0.0024 16.7 70.0 0.0024 16.7 70.0 2.1 2 0 0 2 2 2 1 Caldesmon Peroxin-3 PF04882.12 CDJ49839.1 - 0.005 15.9 6.2 0.005 15.9 6.2 3.1 1 1 1 2 2 2 1 Peroxin-3 SR-25 PF10500.9 CDJ49839.1 - 0.0072 16.0 27.4 0.0072 16.0 27.4 4.2 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein PIP5K PF01504.18 CDJ49839.1 - 0.015 14.6 35.8 1.8e+04 -12.6 35.8 4.0 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF2434 PF10361.9 CDJ49839.1 - 0.075 12.0 1.4 0.19 10.7 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) DUF2722 PF10846.8 CDJ49840.1 - 0.00017 20.7 1.7 0.00017 20.7 1.7 3.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) CNDH2_C PF16858.5 CDJ49840.1 - 1.8 8.3 35.3 0.013 15.4 17.1 2.7 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDK5_activator PF03261.15 CDJ49840.1 - 4.3 6.8 34.0 3.7 7.0 26.0 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Bul1_N PF04425.12 CDJ49840.1 - 5.5 5.6 25.4 0.45 9.2 17.9 2.1 2 0 0 2 2 2 0 Bul1 N terminus RT_RNaseH_2 PF17919.1 CDJ49842.1 - 2.7e-28 97.9 0.1 4.6e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ49842.1 - 3e-27 94.9 0.1 6e-27 94.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ49842.1 - 1.7e-22 80.0 0.0 2.9e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ49842.1 - 5.5e-17 61.6 1.3 1.1e-16 60.6 1.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ49842.1 - 0.00033 20.8 0.6 0.00065 19.9 0.6 1.5 1 0 0 1 1 1 1 H2C2 zinc finger NUDIX PF00293.28 CDJ49843.1 - 0.008 16.2 2.9 0.015 15.4 0.0 2.6 2 0 0 2 2 2 1 NUDIX domain RskA PF10099.9 CDJ49843.1 - 0.028 14.7 0.3 0.028 14.7 0.3 4.8 3 1 0 3 3 3 0 Anti-sigma-K factor rskA GRP PF07172.11 CDJ49843.1 - 1 10.1 0.0 1 10.1 0.0 3.5 4 1 0 4 4 4 0 Glycine rich protein family TIP_N PF12457.8 CDJ49844.1 - 0.014 15.8 3.7 0.019 15.3 3.7 1.2 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal Milton PF12448.8 CDJ49844.1 - 0.15 12.2 8.8 0.16 12.1 8.8 1.1 1 0 0 1 1 1 0 Kinesin associated protein SGS PF05002.15 CDJ49844.1 - 0.16 12.1 5.1 0.33 11.1 0.2 2.5 1 1 2 3 3 3 0 SGS domain DUF1053 PF06327.14 CDJ49845.1 - 0.0079 16.7 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) PAN_3 PF08277.12 CDJ49845.1 - 0.074 12.9 1.1 0.14 12.0 1.1 1.4 1 0 0 1 1 1 0 PAN-like domain RskA PF10099.9 CDJ49846.1 - 4e-10 40.3 8.2 5.3e-07 30.1 0.7 12.2 2 2 6 9 9 9 2 Anti-sigma-K factor rskA TAF4 PF05236.14 CDJ49846.1 - 0.0048 16.7 24.0 0.0048 16.7 24.0 8.7 5 3 3 8 8 8 1 Transcription initiation factor TFIID component TAF4 family RskA PF10099.9 CDJ49847.1 - 0.0017 18.7 17.6 0.0025 18.1 8.6 10.7 2 2 6 9 9 9 2 Anti-sigma-K factor rskA RabGGT_insert PF07711.11 CDJ49847.1 - 7.8 7.1 9.4 0.99 9.9 0.8 3.2 2 0 0 2 2 2 0 Rab geranylgeranyl transferase alpha-subunit, insert domain PAP2 PF01569.21 CDJ49847.1 - 8 6.2 10.3 3.2 7.5 0.1 4.4 4 1 0 4 4 4 0 PAP2 superfamily TMEM51 PF15345.6 CDJ49848.1 - 0.002 18.0 13.6 0.0033 17.3 13.6 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Connexin PF00029.19 CDJ49848.1 - 0.0046 16.7 7.7 0.0056 16.5 7.7 1.1 1 0 0 1 1 1 1 Connexin eIF-3_zeta PF05091.12 CDJ49848.1 - 0.017 14.1 12.7 0.017 14.1 12.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MENTAL PF10457.9 CDJ49848.1 - 0.026 14.3 4.5 0.032 14.0 4.5 1.2 1 0 0 1 1 1 0 Cholesterol-capturing domain CSG2 PF16965.5 CDJ49848.1 - 0.036 13.0 4.2 0.034 13.1 4.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator SID-1_RNA_chan PF13965.6 CDJ49848.1 - 0.049 12.0 1.9 0.053 11.9 1.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 O-antigen_lig PF13425.6 CDJ49848.1 - 0.052 12.3 2.7 0.062 12.1 2.7 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DDHD PF02862.17 CDJ49848.1 - 0.062 13.5 8.3 0.064 13.4 8.3 1.1 1 0 0 1 1 1 0 DDHD domain TFB6 PF17110.5 CDJ49848.1 - 0.086 12.6 4.1 0.12 12.1 4.1 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Serinc PF03348.15 CDJ49848.1 - 0.21 10.5 4.6 0.24 10.3 4.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) V_ATPase_I PF01496.19 CDJ49848.1 - 0.22 9.4 21.9 0.24 9.3 21.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RskA PF10099.9 CDJ49848.1 - 0.51 10.6 28.1 1.9 8.7 28.1 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Neur_chan_memb PF02932.16 CDJ49848.1 - 0.93 9.5 9.9 1.1 9.2 9.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ATG22 PF11700.8 CDJ49848.1 - 8.7 4.9 7.7 16 4.0 7.7 1.4 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like TFIIA PF03153.13 CDJ49849.1 - 0.23 11.4 33.7 0.28 11.1 33.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ49849.1 - 4.3 5.5 18.1 4.4 5.5 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neuraminidase PF18413.1 CDJ49850.1 - 0.00032 20.4 12.1 0.00032 20.4 12.1 2.1 2 0 0 2 2 2 1 Neuraminidase-like domain Spt20 PF12090.8 CDJ49850.1 - 0.0011 18.6 20.2 0.0011 18.6 20.2 3.0 2 1 1 3 3 1 1 Spt20 family EB1_binding PF05937.11 CDJ49850.1 - 0.003 18.2 6.5 0.003 18.2 6.5 1.9 2 0 0 2 2 2 1 EB-1 Binding Domain DUF4834 PF16118.5 CDJ49850.1 - 0.0051 17.7 55.1 1.1e+02 3.9 13.8 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2561 PF10812.8 CDJ49850.1 - 0.007 16.4 3.9 0.007 16.4 3.9 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2561) DUF572 PF04502.13 CDJ49850.1 - 0.0097 15.6 32.0 0.013 15.1 32.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) DotU PF09850.9 CDJ49850.1 - 0.016 14.9 4.5 0.016 14.9 4.5 3.2 1 1 0 2 2 1 0 Type VI secretion system protein DotU DUF3357 PF11837.8 CDJ49850.1 - 0.017 15.6 1.3 0.017 15.6 1.3 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) MSP1a PF11670.8 CDJ49850.1 - 0.023 14.0 0.3 0.023 14.0 0.3 2.8 1 1 1 3 3 2 0 Major surface protein 1a (MSP1a) Kei1 PF08552.11 CDJ49850.1 - 0.023 14.6 0.1 0.023 14.6 0.1 2.9 1 1 1 2 2 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4366 PF14283.6 CDJ49850.1 - 0.043 13.9 0.1 0.043 13.9 0.1 2.9 1 1 1 2 2 1 0 Domain of unknown function (DUF4366) SNARE PF05739.19 CDJ49850.1 - 0.2 11.6 0.0 0.2 11.6 0.0 2.8 3 0 0 3 3 2 0 SNARE domain COPI_assoc PF08507.10 CDJ49850.1 - 0.29 11.2 0.1 0.29 11.2 0.1 3.0 3 1 0 3 3 1 0 COPI associated protein FAM60A PF15396.6 CDJ49850.1 - 3.2 7.7 35.0 2.9 7.8 24.4 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DUF4050 PF13259.6 CDJ49850.1 - 4.6 7.5 34.9 2.6 8.3 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) rve PF00665.26 CDJ49851.1 - 2.4e-13 50.3 0.1 5.2e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ49851.1 - 3.6e-11 42.8 0.1 7.6e-11 41.8 0.0 1.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 CDJ49851.1 - 0.0013 18.4 0.2 0.12 12.2 0.1 2.6 2 0 0 2 2 2 1 Integrase core domain Hus1 PF04005.12 CDJ49851.1 - 0.02 14.0 0.1 0.065 12.3 0.0 1.6 1 1 1 2 2 2 0 Hus1-like protein PKS_DE PF18369.1 CDJ49851.1 - 0.056 14.0 2.4 5.9 7.5 0.9 2.5 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain Corona_5a PF06336.11 CDJ49851.1 - 0.08 12.9 0.0 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Coronavirus 5a protein CorA PF01544.18 CDJ49853.1 - 0.015 14.6 5.9 0.031 13.6 5.9 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ApoLp-III PF07464.11 CDJ49853.1 - 0.037 14.1 6.2 0.027 14.6 3.7 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) PIN_8 PF18476.1 CDJ49853.1 - 0.091 12.6 8.0 0.24 11.2 3.9 2.3 2 0 0 2 2 2 0 PIN like domain Fib_alpha PF08702.10 CDJ49853.1 - 0.13 12.5 3.6 0.38 10.9 1.7 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4972 PF16342.5 CDJ49853.1 - 0.17 11.6 1.6 0.34 10.6 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) DUF4795 PF16043.5 CDJ49853.1 - 0.25 10.9 10.3 0.81 9.3 9.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF1664 PF07889.12 CDJ49853.1 - 0.32 11.0 1.0 0.98 9.5 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 CDJ49853.1 - 0.5 10.9 3.2 41 4.7 3.4 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF29 PF01724.16 CDJ49853.1 - 0.64 10.3 4.8 0.48 10.6 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF29 YtxH PF12732.7 CDJ49853.1 - 2.5 8.7 6.3 9.9 6.8 6.3 2.1 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 CDJ49853.1 - 2.8 8.6 13.2 2.1 9.0 8.2 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) MCU PF04678.13 CDJ49853.1 - 9.7 6.3 7.7 13 5.8 6.5 1.8 1 1 0 1 1 1 0 Mitochondrial calcium uniporter ThiF PF00899.21 CDJ49854.1 - 5.1e-54 183.2 0.0 1.8e-30 106.1 0.0 4.6 4 1 0 4 4 4 4 ThiF family 2-Hacid_dh_C PF02826.19 CDJ49854.1 - 2.3e-05 23.8 0.0 0.015 14.7 0.0 2.7 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UBA_e1_thiolCys PF10585.9 CDJ49854.1 - 4.4e-05 23.5 0.6 1.3 8.9 0.0 4.1 4 0 0 4 4 4 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 CDJ49854.1 - 0.00011 22.3 1.9 0.08 13.0 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 CDJ49854.1 - 0.038 13.2 1.0 8.2 5.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase E1_UFD PF09358.10 CDJ49854.1 - 0.083 13.6 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin fold domain Pyr_redox PF00070.27 CDJ49854.1 - 0.22 12.1 2.2 11 6.6 0.9 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase U3_snoRNA_assoc PF08297.11 CDJ49854.1 - 0.7 10.6 5.3 0.89 10.3 0.2 3.4 3 0 0 3 3 3 0 U3 snoRNA associated RIC1 PF07064.13 CDJ49855.1 - 7.8e-09 35.3 0.1 1.4e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 RIC1 Spt20 PF12090.8 CDJ49858.1 - 0.036 13.7 16.9 0.042 13.5 16.9 1.1 1 0 0 1 1 1 0 Spt20 family AP3D1 PF06375.11 CDJ49858.1 - 0.41 10.9 14.8 0.48 10.7 14.8 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Serinc PF03348.15 CDJ49858.1 - 3.7 6.4 3.6 4.1 6.2 3.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CAML PF14963.6 CDJ49858.1 - 3.9 7.5 7.9 4.1 7.4 7.9 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand MMR1 PF08505.10 CDJ49858.1 - 6.8 6.9 13.5 7.9 6.7 13.5 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein V_ATPase_I PF01496.19 CDJ49858.1 - 7.6 4.3 10.2 7.9 4.3 10.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1840 PF08895.11 CDJ49858.1 - 8.6 6.8 12.4 8.5 6.8 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF4834 PF16118.5 CDJ49859.1 - 0.0055 17.7 0.0 0.0055 17.7 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4834) Zip PF02535.22 CDJ49859.1 - 0.065 12.4 8.1 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Hamartin PF04388.12 CDJ49859.1 - 0.53 8.9 17.5 0.84 8.2 17.5 1.2 1 0 0 1 1 1 0 Hamartin protein Dicty_REP PF05086.12 CDJ49859.1 - 2.5 6.0 5.2 3.9 5.3 5.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SID-1_RNA_chan PF13965.6 CDJ49859.1 - 5.7 5.2 9.6 84 1.4 9.6 1.9 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2464 PF10240.9 CDJ49859.1 - 6.1 6.3 12.0 2 7.9 5.5 2.1 2 0 0 2 2 2 0 Multivesicular body subunit 12 CSG2 PF16965.5 CDJ49859.1 - 6.1 5.7 9.0 4.7 6.1 0.0 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator Pkinase PF00069.25 CDJ49860.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain SR-25 PF10500.9 CDJ49860.1 - 0.14 11.7 2.0 0.26 10.9 2.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Methyltransf_23 PF13489.6 CDJ49862.1 - 5.6e-13 49.1 0.0 5.6e-13 49.1 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ49862.1 - 5.8e-07 30.1 1.8 0.032 14.9 0.6 3.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ49862.1 - 2.1e-05 25.1 12.5 4.1e-05 24.2 0.9 3.9 3 1 0 4 4 4 2 Methyltransferase domain FtsJ PF01728.19 CDJ49862.1 - 8.3e-05 22.8 0.4 8.3e-05 22.8 0.4 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 CDJ49862.1 - 0.0038 17.9 0.5 0.0038 17.9 0.5 4.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ49862.1 - 0.005 16.7 0.4 0.005 16.7 0.4 3.8 3 2 0 3 3 3 2 Methyltransferase domain DUF572 PF04502.13 CDJ49863.1 - 0.023 14.3 31.0 0.046 13.4 27.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) Hamartin PF04388.12 CDJ49863.1 - 0.39 9.3 29.8 0.48 9.0 29.8 1.1 1 0 0 1 1 1 0 Hamartin protein FerI PF08151.12 CDJ49863.1 - 2.5 8.3 7.1 15 5.7 1.6 3.1 2 0 0 2 2 2 0 FerI (NUC094) domain Utp14 PF04615.13 CDJ49863.1 - 2.6 6.5 37.5 3.6 6.1 37.5 1.1 1 0 0 1 1 1 0 Utp14 protein Presenilin PF01080.17 CDJ49863.1 - 4 6.1 43.8 2.7 6.7 4.7 2.2 2 0 0 2 2 2 0 Presenilin SARAF PF06682.12 CDJ49863.1 - 9.5 5.8 37.4 0.091 12.4 14.1 2.3 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Helicase_C PF00271.31 CDJ49864.1 - 6.2e-21 74.8 1.8 7.6e-19 68.1 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDJ49864.1 - 3.8e-11 43.1 0.1 1.2e-10 41.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.29 CDJ49864.1 - 2.4e-06 27.4 19.3 2.4e-06 27.4 19.3 4.1 5 1 0 5 5 5 1 DEAD/DEAH box helicase SpoIIP PF07454.11 CDJ49864.1 - 0.013 15.0 0.4 0.013 15.0 0.4 5.5 5 0 0 5 5 5 0 Stage II sporulation protein P (SpoIIP) BUD22 PF09073.10 CDJ49864.1 - 0.13 11.6 111.0 0.036 13.4 18.4 6.0 5 1 0 5 5 5 0 BUD22 TCP PF03634.13 CDJ49864.1 - 2.3 8.8 0.0 2.3 8.8 0.0 7.7 3 2 3 6 6 6 0 TCP family transcription factor RNase_P_p30 PF01876.16 CDJ49865.1 - 9.4e-07 28.5 0.7 0.0004 19.9 0.0 3.2 3 1 0 3 3 3 2 RNase P subunit p30 MEDS PF14417.6 CDJ49865.1 - 0.041 13.7 2.1 0.052 13.4 0.4 2.2 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Spt20 PF12090.8 CDJ49865.1 - 1.2 8.7 13.0 2.5 7.7 13.0 1.5 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ49865.1 - 4.1 7.3 33.2 0.061 13.3 21.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ49866.1 - 0.0035 17.4 8.1 0.0035 17.4 8.1 2.2 2 1 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 CDJ49866.1 - 0.0093 14.8 5.6 0.012 14.4 5.6 1.1 1 0 0 1 1 1 1 Presenilin Spt20 PF12090.8 CDJ49866.1 - 0.013 15.2 19.0 0.079 12.6 12.1 2.1 2 0 0 2 2 2 0 Spt20 family PSK PF06404.12 CDJ49866.1 - 0.016 16.2 2.1 0.14 13.2 0.1 2.2 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) EPL1 PF10513.9 CDJ49866.1 - 0.055 13.9 5.0 1.3 9.4 1.3 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like CPSF100_C PF13299.6 CDJ49866.1 - 0.096 12.9 4.8 0.58 10.3 0.5 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EBP50_C PF09007.11 CDJ49866.1 - 0.14 13.2 13.2 1.9 9.5 1.1 2.1 2 0 0 2 2 2 0 EBP50, C-terminal Hydin_ADK PF17213.3 CDJ49866.1 - 0.34 11.2 7.9 1.4 9.2 0.3 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AIF_C PF14721.6 CDJ49866.1 - 0.38 11.1 6.2 0.94 9.8 0.5 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TFIIA PF03153.13 CDJ49866.1 - 0.47 10.4 14.0 0.67 9.9 14.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRC2_HTH_1 PF18118.1 CDJ49866.1 - 0.74 10.7 7.4 2.6 8.9 1.7 2.2 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain DUF1635 PF07795.11 CDJ49866.1 - 0.75 9.6 15.5 0.54 10.1 5.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF4834 PF16118.5 CDJ49866.1 - 0.78 10.7 12.1 0.51 11.3 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) BRF1 PF07741.13 CDJ49866.1 - 0.79 10.1 7.1 0.29 11.5 1.6 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain CCDC53 PF10152.9 CDJ49866.1 - 1.1 9.6 11.5 1 9.8 4.6 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Roughex PF06020.11 CDJ49866.1 - 1.2 8.2 8.7 0.057 12.5 3.4 1.5 2 0 0 2 2 2 0 Drosophila roughex protein SPX PF03105.19 CDJ49866.1 - 1.2 9.0 12.1 0.16 11.8 3.0 2.0 2 0 0 2 2 2 0 SPX domain DUF2722 PF10846.8 CDJ49866.1 - 1.6 7.6 19.9 2.4 7.0 12.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) ANAPC_CDC26 PF10471.9 CDJ49866.1 - 1.9 9.3 21.4 0.28 12.0 10.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 RAP1 PF07218.11 CDJ49866.1 - 2.2 6.5 7.1 3 6.0 7.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PNISR PF15996.5 CDJ49866.1 - 2.7 8.2 11.6 2.1 8.6 4.3 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Pannexin_like PF12534.8 CDJ49866.1 - 4.9 6.1 6.5 6.7 5.7 0.3 2.0 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 AF-4 PF05110.13 CDJ49866.1 - 5.8 4.9 25.1 3.9 5.5 17.1 1.9 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Siah-Interact_N PF09032.11 CDJ49866.1 - 7.1 7.0 12.7 1.1 9.7 4.9 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal Menin PF05053.13 CDJ49866.1 - 8 4.7 10.5 0.61 8.4 2.5 2.0 2 0 0 2 2 2 0 Menin MAT1 PF06391.13 CDJ49867.1 - 0.0057 16.5 16.8 0.0066 16.3 16.8 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 Peptidase_S49_N PF08496.10 CDJ49867.1 - 0.0079 16.3 15.0 0.0096 16.0 15.0 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Paf1 PF03985.13 CDJ49867.1 - 0.008 15.2 13.2 0.0083 15.2 13.2 1.0 1 0 0 1 1 1 1 Paf1 eIF-3_zeta PF05091.12 CDJ49867.1 - 0.03 13.3 18.6 0.03 13.3 18.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.6 CDJ49867.1 - 0.039 12.4 4.5 0.044 12.2 4.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Baculo_PP31 PF05311.11 CDJ49867.1 - 0.08 12.4 14.3 0.1 12.1 14.3 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Spem1 PF15670.5 CDJ49867.1 - 0.083 12.5 14.4 0.084 12.4 14.4 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 SpoIIP PF07454.11 CDJ49867.1 - 0.09 12.2 14.1 0.096 12.1 14.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Endostatin PF06482.11 CDJ49867.1 - 0.1 12.0 15.2 0.11 12.0 15.2 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin RR_TM4-6 PF06459.12 CDJ49867.1 - 0.16 11.8 16.1 0.17 11.7 16.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FHIPEP PF00771.20 CDJ49867.1 - 0.16 10.4 8.6 0.18 10.2 8.6 1.2 1 0 0 1 1 1 0 FHIPEP family Velvet PF11754.8 CDJ49867.1 - 0.16 11.9 16.4 0.17 11.8 16.4 1.1 1 0 0 1 1 1 0 Velvet factor Folate_carrier PF01770.18 CDJ49867.1 - 0.22 10.2 6.9 0.24 10.1 6.9 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF4569 PF15133.6 CDJ49867.1 - 0.23 11.2 17.8 0.28 10.9 17.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) NARP1 PF12569.8 CDJ49867.1 - 0.23 10.3 16.6 0.26 10.2 16.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 O-antigen_lig PF13425.6 CDJ49867.1 - 0.25 10.1 4.5 0.26 10.0 4.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CLN3 PF02487.17 CDJ49867.1 - 0.28 10.2 10.9 0.3 10.1 10.9 1.1 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 CDJ49867.1 - 0.31 11.1 10.4 0.33 11.0 10.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF913 PF06025.12 CDJ49867.1 - 0.31 10.0 8.6 0.32 9.9 8.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TERB2 PF15101.6 CDJ49867.1 - 0.34 10.9 20.0 0.39 10.7 20.0 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAM60A PF15396.6 CDJ49867.1 - 0.36 10.8 11.2 0.4 10.7 11.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TraT PF05818.12 CDJ49867.1 - 0.36 10.5 17.0 0.46 10.1 17.0 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF1980 PF09323.10 CDJ49867.1 - 0.36 10.7 8.3 0.43 10.5 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SLC12 PF03522.15 CDJ49867.1 - 0.37 9.8 15.1 0.38 9.7 15.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Serinc PF03348.15 CDJ49867.1 - 0.37 9.7 10.2 0.44 9.4 10.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ureide_permease PF07168.11 CDJ49867.1 - 0.45 9.2 6.3 0.54 9.0 6.3 1.2 1 0 0 1 1 1 0 Ureide permease Glt_symporter PF03616.14 CDJ49867.1 - 0.51 9.0 5.4 0.7 8.5 5.4 1.3 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF4820 PF16091.5 CDJ49867.1 - 0.52 9.6 14.1 0.59 9.5 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) EOS1 PF12326.8 CDJ49867.1 - 0.58 10.1 9.1 0.72 9.8 9.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein SelP_N PF04592.14 CDJ49867.1 - 0.62 9.4 20.4 0.88 8.9 20.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Presenilin PF01080.17 CDJ49867.1 - 0.68 8.6 21.4 0.82 8.4 21.4 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 CDJ49867.1 - 0.68 10.0 14.9 0.75 9.9 14.9 1.1 1 0 0 1 1 1 0 DDHD domain Helicase_RecD PF05127.14 CDJ49867.1 - 0.71 9.7 11.6 1.2 9.0 11.6 1.3 1 0 0 1 1 1 0 Helicase Dynamin_N PF00350.23 CDJ49867.1 - 0.77 9.8 7.7 0.95 9.5 7.7 1.2 1 0 0 1 1 1 0 Dynamin family Ctr PF04145.15 CDJ49867.1 - 0.89 10.2 10.3 1.1 9.9 10.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family TFB6 PF17110.5 CDJ49867.1 - 0.96 9.2 7.1 1.1 9.0 7.1 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Suf PF05843.14 CDJ49867.1 - 0.96 9.4 21.6 1.1 9.2 21.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.7 CDJ49867.1 - 1.1 7.4 15.0 1.1 7.3 15.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPL5 PF18168.1 CDJ49867.1 - 1.1 8.5 14.9 1.4 8.2 14.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Connexin PF00029.19 CDJ49867.1 - 1.2 8.9 15.3 1.4 8.7 15.3 1.1 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 CDJ49867.1 - 1.2 8.8 8.8 1.5 8.4 8.8 1.2 1 0 0 1 1 1 0 FAM176 family MMR1 PF08505.10 CDJ49867.1 - 1.3 9.3 22.0 1.5 9.1 22.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF2232 PF09991.9 CDJ49867.1 - 1.4 8.1 8.7 2.5 7.2 8.7 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) NEMP PF10225.9 CDJ49867.1 - 1.4 8.5 7.3 1.8 8.2 7.3 1.1 1 0 0 1 1 1 0 NEMP family BORG_CEP PF14957.6 CDJ49867.1 - 1.5 10.0 9.9 1.8 9.8 9.9 1.1 1 0 0 1 1 1 0 Cdc42 effector TFIIA PF03153.13 CDJ49867.1 - 1.6 8.7 46.4 1.7 8.5 46.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OATP PF03137.20 CDJ49867.1 - 1.6 6.9 7.2 1.7 6.8 7.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Zip PF02535.22 CDJ49867.1 - 1.6 7.8 11.5 2 7.6 11.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CSG2 PF16965.5 CDJ49867.1 - 1.7 7.5 8.6 1.8 7.4 8.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator YABBY PF04690.13 CDJ49867.1 - 1.7 9.2 13.0 2 9.0 13.0 1.2 1 0 0 1 1 1 0 YABBY protein Peptidase_S15 PF02129.18 CDJ49867.1 - 1.8 8.1 15.3 2 7.9 15.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Nucleoside_tran PF01733.18 CDJ49867.1 - 2.2 7.6 4.9 2.2 7.6 4.9 1.1 1 0 0 1 1 1 0 Nucleoside transporter Tim54 PF11711.8 CDJ49867.1 - 2.2 7.0 14.5 2.5 6.8 14.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 V_ATPase_I PF01496.19 CDJ49867.1 - 3 5.7 19.3 3.4 5.5 19.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gti1_Pac2 PF09729.9 CDJ49867.1 - 3 7.9 13.9 3.6 7.6 13.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family ALMT PF11744.8 CDJ49867.1 - 3.1 6.5 13.5 3.2 6.5 13.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HCO3_cotransp PF00955.21 CDJ49867.1 - 3.5 6.3 8.3 3.9 6.2 8.3 1.0 1 0 0 1 1 1 0 HCO3- transporter family IHABP4_N PF16174.5 CDJ49867.1 - 3.6 8.2 24.6 4.7 7.8 24.6 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal PAT1 PF09770.9 CDJ49867.1 - 3.6 5.7 32.6 3.7 5.7 32.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.16 CDJ49867.1 - 3.7 6.4 9.9 3.7 6.4 9.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Membralin PF09746.9 CDJ49867.1 - 3.9 6.4 10.7 4.2 6.3 10.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein MDM31_MDM32 PF08118.11 CDJ49867.1 - 4.1 6.0 11.5 4.7 5.8 11.5 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Band_3_cyto PF07565.13 CDJ49867.1 - 4.5 7.0 18.5 5.3 6.8 18.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pannexin_like PF12534.8 CDJ49867.1 - 5.1 6.1 13.8 6 5.9 13.8 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DDRGK PF09756.9 CDJ49867.1 - 5.2 6.6 24.3 6.7 6.3 24.3 1.1 1 0 0 1 1 1 0 DDRGK domain FliP PF00813.20 CDJ49867.1 - 5.4 6.9 8.6 6.1 6.7 8.6 1.2 1 0 0 1 1 1 0 FliP family DcuA_DcuB PF03605.14 CDJ49867.1 - 5.5 5.8 10.5 10 4.9 10.5 1.5 1 1 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter MAJIN PF15077.6 CDJ49867.1 - 6.1 6.6 13.5 6.9 6.4 13.5 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Paramyxo_ncap PF00973.19 CDJ49867.1 - 7 5.4 14.0 7.8 5.3 14.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Sec62 PF03839.16 CDJ49867.1 - 7.1 6.1 14.5 8.3 5.8 14.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RICTOR_N PF14664.6 CDJ49867.1 - 7.4 5.4 9.0 9 5.2 9.0 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF2828 PF11443.8 CDJ49867.1 - 7.8 4.5 20.3 9.2 4.2 20.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4228 PF14009.6 CDJ49867.1 - 7.9 6.8 11.7 10 6.5 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) EPL1 PF10513.9 CDJ49867.1 - 7.9 6.8 19.2 10 6.5 19.2 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Hydin_ADK PF17213.3 CDJ49867.1 - 8 6.7 21.6 10 6.3 21.6 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain GREB1 PF15782.5 CDJ49867.1 - 8.5 3.3 19.6 8.8 3.3 19.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Consortin_C PF15281.6 CDJ49867.1 - 8.8 6.4 7.1 14 5.7 7.1 1.3 1 0 0 1 1 1 0 Consortin C-terminus SelP_N PF04592.14 CDJ49868.1 - 3 7.2 42.3 3.3 7.0 42.3 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NeA_P2 PF12312.8 CDJ49869.1 - 0.00096 18.7 2.7 0.0013 18.2 2.7 1.2 1 0 0 1 1 1 1 Nepovirus subgroup A polyprotein DUF1856 PF08983.10 CDJ49869.1 - 0.96 9.7 6.0 15 5.9 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) Rnk_N PF14760.6 CDJ49869.1 - 1 9.9 2.4 3.4 8.2 2.4 2.0 1 1 0 1 1 1 0 Rnk N-terminus FAM101 PF15068.6 CDJ49869.1 - 7.9 6.4 13.4 0.54 10.2 6.4 2.0 1 1 1 2 2 2 0 FAM101 family Sin_N PF04801.13 CDJ49871.1 - 0.003 16.8 18.5 0.003 16.8 18.5 3.4 2 1 1 3 3 3 1 Sin-like protein conserved region Isy1 PF06246.12 CDJ49871.1 - 0.18 11.3 0.0 0.18 11.3 0.0 3.8 2 2 2 4 4 4 0 Isy1-like splicing family TRM PF02005.16 CDJ49872.1 - 1.3e-06 27.8 0.0 3.2e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase TFIIA PF03153.13 CDJ49872.1 - 0.00044 20.4 4.5 0.00047 20.3 4.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 CDJ49872.1 - 0.0022 17.3 0.6 0.0027 17.0 0.6 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Apt1 PF10351.9 CDJ49872.1 - 0.04 12.8 5.8 0.049 12.5 5.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sporozoite_P67 PF05642.11 CDJ49872.1 - 0.15 10.1 11.4 0.19 9.8 11.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SPX PF03105.19 CDJ49872.1 - 0.43 10.5 9.3 0.55 10.1 9.3 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CDJ49872.1 - 0.67 8.5 9.9 0.91 8.0 9.9 1.1 1 0 0 1 1 1 0 Macoilin family BORG_CEP PF14957.6 CDJ49872.1 - 0.77 10.9 8.1 1.2 10.3 8.1 1.2 1 0 0 1 1 1 0 Cdc42 effector Plasmodium_Vir PF05795.11 CDJ49872.1 - 1.2 8.5 9.3 1.6 8.1 9.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Spt20 PF12090.8 CDJ49872.1 - 1.3 8.6 18.6 1.8 8.1 18.6 1.1 1 0 0 1 1 1 0 Spt20 family NST1 PF13945.6 CDJ49872.1 - 1.4 9.0 11.7 2.3 8.3 11.7 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator PBP_sp32 PF07222.12 CDJ49872.1 - 2.5 7.5 10.2 3.9 6.9 10.2 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Roughex PF06020.11 CDJ49872.1 - 2.6 7.1 7.7 3.5 6.6 7.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Lin-8 PF03353.15 CDJ49872.1 - 4.6 6.7 10.2 6.2 6.3 10.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ima1_N PF09779.9 CDJ49872.1 - 4.9 8.0 10.2 9.3 7.1 10.2 1.5 1 1 0 1 1 1 0 Ima1 N-terminal domain Presenilin PF01080.17 CDJ49872.1 - 7.5 5.2 11.5 12 4.5 11.5 1.3 1 0 0 1 1 1 0 Presenilin Miga PF10265.9 CDJ49872.1 - 7.9 5.3 6.5 11 4.9 6.5 1.1 1 0 0 1 1 1 0 Mitoguardin GREB1 PF15782.5 CDJ49872.1 - 9.5 3.2 9.9 12 2.9 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CDJ49873.1 - 0.0024 17.9 3.9 0.003 17.6 3.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ49873.1 - 0.0044 16.7 7.1 0.0066 16.1 7.1 1.3 1 0 0 1 1 1 1 Spt20 family Transposase_21 PF02992.14 CDJ49873.1 - 2.6 7.2 5.1 2.9 7.1 1.0 2.1 1 1 0 2 2 2 0 Transposase family tnp2 SprA-related PF12118.8 CDJ49873.1 - 3.7 6.6 16.7 10 5.2 16.7 1.6 1 1 0 1 1 1 0 SprA-related family RskA PF10099.9 CDJ49874.1 - 5.1e-08 33.4 4.1 5.1e-08 33.4 4.1 2.4 1 1 0 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ49874.1 - 0.038 14.0 33.4 0.056 13.4 33.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 CDJ49874.1 - 0.93 8.3 35.0 1.3 7.8 11.6 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Cpn60_TCP1 PF00118.24 CDJ49876.1 - 4.1e-140 467.7 7.2 4.7e-140 467.5 7.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LUC7 PF03194.15 CDJ49877.1 - 3.8e-45 154.5 2.1 3.8e-45 154.5 2.1 2.0 2 0 0 2 2 2 1 LUC7 N_terminus Occludin_ELL PF07303.13 CDJ49877.1 - 0.02 15.6 1.3 0.052 14.3 1.3 1.6 1 0 0 1 1 1 0 Occludin homology domain ABC_tran_CTD PF16326.5 CDJ49877.1 - 0.026 14.8 2.8 0.29 11.4 3.3 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain FCD PF07729.12 CDJ49877.1 - 0.1 13.0 1.0 0.37 11.2 0.9 2.0 1 1 0 1 1 1 0 FCD domain HSCB_C PF07743.13 CDJ49877.1 - 0.4 11.2 9.1 0.16 12.5 3.9 2.6 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain SKA1 PF07160.12 CDJ49877.1 - 1.4 8.7 10.1 0.088 12.6 0.5 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Presenilin PF01080.17 CDJ49877.1 - 8.8 5.0 9.5 0.49 9.1 3.7 1.7 2 0 0 2 2 2 0 Presenilin DnaJ-X PF14308.6 CDJ49878.1 - 4.7e-45 153.6 6.2 4.7e-45 153.6 6.2 2.2 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CDJ49878.1 - 3.9e-25 87.7 0.5 8.7e-25 86.6 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.11 CDJ49878.1 - 1.1e-07 32.1 0.0 8e-07 29.3 0.0 2.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain SR-25 PF10500.9 CDJ49878.1 - 0.0022 17.7 5.7 0.0022 17.7 5.7 3.8 4 0 0 4 4 4 3 Nuclear RNA-splicing-associated protein Mito_carr PF00153.27 CDJ49878.1 - 0.16 11.9 0.1 0.54 10.2 0.1 2.0 1 0 0 1 1 1 0 Mitochondrial carrier protein Spt20 PF12090.8 CDJ49878.1 - 0.38 10.3 21.5 5.3 6.6 16.8 2.7 2 0 0 2 2 2 0 Spt20 family SAD_SRA PF02182.17 CDJ49878.1 - 0.4 10.4 5.1 0.1 12.3 1.3 1.9 2 0 0 2 2 2 0 SAD/SRA domain Med15 PF09606.10 CDJ49878.1 - 2.1 6.9 24.3 1.2 7.8 18.4 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.19 CDJ49879.1 - 0.8 10.3 16.9 0.49 11.0 3.0 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4148 PF13663.6 CDJ49879.1 - 2.7 8.2 14.6 5.3 7.3 3.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Presenilin PF01080.17 CDJ49880.1 - 0.042 12.6 24.6 0.047 12.5 24.6 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ49880.1 - 0.049 13.6 14.8 0.058 13.4 14.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Vfa1 PF08432.10 CDJ49880.1 - 0.1 12.9 22.7 0.12 12.7 22.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 CDJ49880.1 - 0.11 10.8 17.5 0.11 10.7 17.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.6 CDJ49880.1 - 0.12 11.1 16.5 0.13 11.0 16.5 1.0 1 0 0 1 1 1 0 Raftlin Smg8_Smg9 PF10220.9 CDJ49880.1 - 0.13 10.6 16.4 0.13 10.5 16.4 1.0 1 0 0 1 1 1 0 Smg8_Smg9 PAT1 PF09770.9 CDJ49880.1 - 0.22 9.8 38.7 0.25 9.6 38.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hamartin PF04388.12 CDJ49880.1 - 0.25 10.0 17.8 0.27 9.8 17.8 1.0 1 0 0 1 1 1 0 Hamartin protein SMYLE_N PF18615.1 CDJ49880.1 - 0.37 10.3 14.3 0.45 10.0 14.3 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain GREB1 PF15782.5 CDJ49880.1 - 0.62 7.1 22.1 0.69 7.0 22.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Otopetrin PF03189.13 CDJ49880.1 - 0.73 8.6 8.3 0.84 8.4 8.3 1.2 1 0 0 1 1 1 0 Otopetrin Exonuc_VII_L PF02601.15 CDJ49880.1 - 0.83 9.2 21.9 0.97 8.9 21.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit PA26 PF04636.13 CDJ49880.1 - 1.2 8.0 15.4 1.3 7.8 15.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Peptidase_S64 PF08192.11 CDJ49880.1 - 1.3 7.4 18.5 1.5 7.3 18.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Nop53 PF07767.11 CDJ49880.1 - 1.4 8.3 28.9 1.6 8.0 28.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PMSI1 PF15322.6 CDJ49880.1 - 1.8 7.9 13.8 2.3 7.6 13.8 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF913 PF06025.12 CDJ49880.1 - 1.8 7.4 14.1 2.6 7.0 14.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 CDJ49880.1 - 2.3 6.9 20.1 2.6 6.7 20.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CCSAP PF15748.5 CDJ49880.1 - 2.4 8.3 28.7 3 8.0 28.7 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Asp-B-Hydro_N PF05279.11 CDJ49880.1 - 2.4 8.1 19.6 2.9 7.9 19.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ndc1_Nup PF09531.10 CDJ49880.1 - 2.6 6.6 21.4 2.8 6.5 21.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4045 PF13254.6 CDJ49880.1 - 2.7 7.5 24.2 3.2 7.3 24.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) YscJ_FliF_C PF08345.11 CDJ49880.1 - 3.4 8.0 23.6 5.2 7.4 23.6 1.3 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal DUF2052 PF09747.9 CDJ49880.1 - 3.8 7.6 25.5 4.9 7.2 25.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ49880.1 - 4.1 7.2 28.5 5.2 6.8 28.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hydin_ADK PF17213.3 CDJ49880.1 - 4.4 7.5 20.4 5.5 7.2 20.4 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Hid1 PF12722.7 CDJ49880.1 - 4.4 5.3 25.4 5.3 5.0 25.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 CDJ49880.1 - 5 7.1 18.4 6.9 6.6 18.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MMR1 PF08505.10 CDJ49880.1 - 5.4 7.2 27.6 7.4 6.8 27.6 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SOG2 PF10428.9 CDJ49880.1 - 5.4 6.1 19.8 6.4 5.8 19.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SLC12 PF03522.15 CDJ49880.1 - 5.8 5.8 24.3 6.9 5.6 24.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF1387 PF07139.11 CDJ49880.1 - 6 6.5 22.7 8.3 6.0 22.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) BORG_CEP PF14957.6 CDJ49880.1 - 6 8.0 16.7 9.6 7.4 16.7 1.3 1 0 0 1 1 1 0 Cdc42 effector Endostatin PF06482.11 CDJ49880.1 - 7.4 5.9 20.5 9.3 5.6 20.5 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin MAT1 PF06391.13 CDJ49881.1 - 0.21 11.4 36.3 0.25 11.1 36.3 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF913 PF06025.12 CDJ49881.1 - 0.26 10.2 15.8 0.3 10.0 15.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ASD2 PF08687.11 CDJ49881.1 - 0.36 10.4 29.0 0.43 10.1 29.0 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF5427 PF10310.9 CDJ49881.1 - 0.44 9.4 26.1 0.51 9.2 26.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Mit_ribos_Mrp51 PF11709.8 CDJ49881.1 - 0.45 10.1 21.1 0.52 9.8 21.1 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit CobN-Mg_chel PF02514.16 CDJ49881.1 - 0.93 7.1 18.0 0.98 7.1 18.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase SMYLE_N PF18615.1 CDJ49881.1 - 0.99 8.9 18.4 1.3 8.6 18.4 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF3295 PF11702.8 CDJ49881.1 - 1.3 8.3 25.0 1.6 8.0 25.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Presenilin PF01080.17 CDJ49881.1 - 1.4 7.6 32.0 1.6 7.4 32.0 1.0 1 0 0 1 1 1 0 Presenilin SARAF PF06682.12 CDJ49881.1 - 1.7 8.3 21.6 1.9 8.1 21.6 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Trehalase PF01204.18 CDJ49881.1 - 2.6 6.8 19.1 3.2 6.5 19.1 1.0 1 0 0 1 1 1 0 Trehalase RR_TM4-6 PF06459.12 CDJ49881.1 - 2.6 7.8 28.7 3.1 7.6 28.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Noggin PF05806.12 CDJ49881.1 - 2.7 7.9 12.5 3.3 7.6 12.5 1.1 1 0 0 1 1 1 0 Noggin FAM60A PF15396.6 CDJ49881.1 - 3.1 7.7 24.5 3.7 7.5 24.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Rgp1 PF08737.10 CDJ49881.1 - 3.7 6.6 26.6 4.2 6.4 26.6 1.0 1 0 0 1 1 1 0 Rgp1 NARP1 PF12569.8 CDJ49881.1 - 3.9 6.3 23.1 5.4 5.8 23.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SLC12 PF03522.15 CDJ49881.1 - 3.9 6.4 30.6 4.1 6.3 30.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 XRN_M PF17846.1 CDJ49881.1 - 4.2 6.2 22.3 4.8 6.0 22.3 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DUF572 PF04502.13 CDJ49881.1 - 4.3 6.9 24.9 5.1 6.6 24.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Exonuc_VII_L PF02601.15 CDJ49881.1 - 4.7 6.7 30.8 5.6 6.4 30.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit CLN3 PF02487.17 CDJ49881.1 - 4.8 6.1 19.7 6.8 5.6 19.7 1.3 1 0 0 1 1 1 0 CLN3 protein Hamartin PF04388.12 CDJ49881.1 - 4.8 5.7 25.3 5.5 5.5 25.3 1.0 1 0 0 1 1 1 0 Hamartin protein HSP70 PF00012.20 CDJ49881.1 - 5.4 5.1 21.8 6.3 4.8 21.8 1.0 1 0 0 1 1 1 0 Hsp70 protein Rtf2 PF04641.12 CDJ49881.1 - 6 6.1 24.0 7.6 5.8 24.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2052 PF09747.9 CDJ49881.1 - 6.2 6.9 29.1 8 6.5 29.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Tyrosinase PF00264.20 CDJ49881.1 - 6.3 7.0 15.0 7.3 6.8 15.0 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase DUF2828 PF11443.8 CDJ49881.1 - 6.9 4.6 23.1 9.3 4.2 23.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PA26 PF04636.13 CDJ49881.1 - 7.2 5.4 23.3 8.4 5.2 23.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDC45 PF02724.14 CDJ49881.1 - 7.9 4.6 25.5 9.3 4.4 25.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Polysacc_synt PF01943.17 CDJ49882.1 - 0.19 11.0 0.6 0.27 10.6 0.6 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2368 PF10166.9 CDJ49882.1 - 3.6 7.2 12.1 7.3 6.2 12.1 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) RAP1 PF07218.11 CDJ49882.1 - 3.7 5.7 16.0 4.7 5.4 16.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) 7tm_7 PF08395.12 CDJ49882.1 - 6.5 5.8 5.2 7.8 5.6 5.2 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor EST1 PF10374.9 CDJ49882.1 - 7.2 7.3 14.6 0.23 12.1 8.5 1.6 2 0 0 2 2 2 0 Telomerase activating protein Est1 Metallophos PF00149.28 CDJ49884.1 - 3.1e-07 31.1 0.0 4e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 CDJ49885.1 - 6.2e-10 39.4 0.5 3.5e-09 37.0 0.3 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ49885.1 - 6.9e-06 25.6 1.6 0.032 14.2 0.5 3.8 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDJ49885.1 - 1.9e-05 23.9 1.0 0.13 11.8 0.1 3.9 4 0 0 4 4 4 2 EF hand SR-25 PF10500.9 CDJ49886.1 - 0.0013 18.4 11.6 0.0015 18.2 11.6 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ49886.1 - 0.047 14.4 9.1 0.057 14.1 9.1 1.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein UPF0524 PF15823.5 CDJ49886.1 - 0.32 10.4 4.8 0.39 10.1 4.8 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 MID_MedPIWI PF18296.1 CDJ49886.1 - 0.72 9.6 11.4 0.79 9.5 11.4 1.1 1 0 0 1 1 1 0 MID domain of medPIWI CCDC106 PF15794.5 CDJ49886.1 - 0.98 9.1 14.1 1.2 8.8 14.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 YABBY PF04690.13 CDJ49886.1 - 3 8.4 8.2 3.5 8.2 8.2 1.0 1 0 0 1 1 1 0 YABBY protein CDK2AP PF09806.9 CDJ49886.1 - 3.2 7.8 19.5 3.7 7.6 19.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3362 PF11842.8 CDJ49886.1 - 3.3 8.0 18.0 3.9 7.8 18.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) PA26 PF04636.13 CDJ49886.1 - 8.7 5.1 8.9 8.9 5.1 8.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Neur_chan_memb PF02932.16 CDJ49886.1 - 8.9 6.3 10.4 9.9 6.1 10.4 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Plasmodium_Vir PF05795.11 CDJ49887.1 - 0.78 9.1 8.2 0.89 8.9 8.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Apt1 PF10351.9 CDJ49887.1 - 6.3 5.5 16.4 7.6 5.3 16.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ49887.1 - 8.4 6.2 16.6 10 5.9 16.6 1.1 1 0 0 1 1 1 0 SPX domain ETRAMP PF09716.10 CDJ49888.1 - 2 8.5 0.0 2 8.5 0.0 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SR-25 PF10500.9 CDJ49888.1 - 5.4 6.6 18.4 6.1 6.4 17.7 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ49889.1 - 5e-05 23.3 1.3 5e-05 23.3 1.3 14.3 9 5 1 10 10 10 2 Unstructured region C-term to UIM in Ataxin3 Otopetrin PF03189.13 CDJ49889.1 - 8e-05 21.6 0.2 60 2.3 0.0 4.6 2 2 1 3 3 3 0 Otopetrin SARAF PF06682.12 CDJ49889.1 - 0.003 17.3 7.9 0.003 17.3 7.9 6.8 5 3 1 6 6 6 1 SOCE-associated regulatory factor of calcium homoeostasis TruB_N PF01509.18 CDJ49889.1 - 0.037 14.4 11.8 0.43 10.9 0.0 3.9 4 0 0 4 4 4 0 TruB family pseudouridylate synthase (N terminal domain) Rad60-SLD PF11976.8 CDJ49890.1 - 1.7e-09 37.4 0.0 2.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_60s PF00428.19 CDJ49890.1 - 0.0079 16.8 3.7 0.0079 16.8 3.7 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF5645 PF18713.1 CDJ49890.1 - 0.054 13.8 0.0 0.076 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) zf-CSL PF05207.13 CDJ49891.1 - 6.9e-11 41.7 0.0 1.8e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 CSL zinc finger RskA PF10099.9 CDJ49891.1 - 0.0011 19.3 11.8 0.0011 19.3 11.8 6.4 2 2 2 4 4 4 1 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ49891.1 - 2.2 7.4 25.7 0.47 9.6 9.0 2.7 2 0 0 2 2 2 0 Sin-like protein conserved region RAP PF08373.10 CDJ49893.1 - 0.069 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 RAP domain SelP_N PF04592.14 CDJ49894.1 - 0.011 15.1 21.4 0.013 14.9 21.4 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pex14_N PF04695.13 CDJ49894.1 - 0.14 12.8 28.3 0.16 12.6 28.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sin_N PF04801.13 CDJ49894.1 - 2.9 7.0 27.2 3.1 6.9 27.2 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF2052 PF09747.9 CDJ49894.1 - 3.8 7.6 17.8 4.2 7.4 17.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CPSF100_C PF13299.6 CDJ49894.1 - 4 7.6 13.7 5.2 7.2 13.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Lin-8 PF03353.15 CDJ49894.1 - 6.5 6.2 24.8 7.5 6.0 24.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist O-antigen_lig PF13425.6 CDJ49894.1 - 7.2 5.3 9.2 8.4 5.1 9.2 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CNDH2_M PF16869.5 CDJ49894.1 - 7.4 7.3 14.7 9.1 7.0 14.7 1.2 1 0 0 1 1 1 0 PF16858 AAA PF00004.29 CDJ49895.1 - 3.5e-12 46.9 0.0 6.6e-12 46.0 0.0 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 CDJ49895.1 - 1.5e-05 24.4 0.0 1.5e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CDJ49895.1 - 2e-05 24.4 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ49895.1 - 2.8e-05 24.6 0.0 2.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 CDJ49895.1 - 0.00022 21.2 0.0 0.00028 20.9 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CDJ49895.1 - 0.00057 19.7 0.0 0.057 13.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDJ49895.1 - 0.0007 19.9 0.0 0.00086 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CDJ49895.1 - 0.00086 19.1 0.0 0.00086 19.1 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDJ49895.1 - 0.0011 18.3 0.3 0.0015 18.0 0.3 1.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CDJ49895.1 - 0.0013 18.9 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDJ49895.1 - 0.0016 18.5 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CDJ49895.1 - 0.0032 17.7 0.1 0.0048 17.2 0.0 1.4 2 0 0 2 2 1 1 AAA domain CPT PF07931.12 CDJ49895.1 - 0.0059 16.5 0.0 0.0074 16.1 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 CDJ49895.1 - 0.0061 17.1 0.2 0.011 16.3 0.0 1.5 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.26 CDJ49895.1 - 0.0075 16.0 0.0 0.0075 16.0 0.0 1.1 1 0 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.12 CDJ49895.1 - 0.0089 16.0 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 CDJ49895.1 - 0.012 14.9 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 CDJ49895.1 - 0.013 15.3 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 CDJ49895.1 - 0.018 15.1 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Torsin RNA_helicase PF00910.22 CDJ49895.1 - 0.027 14.8 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 CDJ49895.1 - 0.03 13.8 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 CDJ49895.1 - 0.032 13.3 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ResIII PF04851.15 CDJ49895.1 - 0.035 14.1 0.0 0.043 13.8 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_17 PF13207.6 CDJ49895.1 - 0.036 14.5 0.0 0.061 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CDJ49895.1 - 0.037 13.3 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 CDJ49895.1 - 0.045 13.3 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ49895.1 - 0.063 13.8 0.1 0.083 13.4 0.1 1.2 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 CDJ49895.1 - 0.065 12.4 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 CDJ49895.1 - 0.069 12.5 0.1 0.095 12.0 0.1 1.4 1 1 0 1 1 1 0 KaiC AAA_30 PF13604.6 CDJ49895.1 - 0.082 12.6 0.1 0.096 12.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CDJ49895.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_3 PF07726.11 CDJ49895.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDJ49895.1 - 0.15 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 CDJ49895.1 - 0.16 12.3 0.4 0.21 11.9 0.4 1.2 1 0 0 1 1 1 0 AAA domain LigT_PEase PF02834.16 CDJ49896.1 - 4.3 7.6 7.8 0.26 11.5 0.4 2.9 2 0 0 2 2 2 0 LigT like Phosphoesterase Chromo PF00385.24 CDJ49898.1 - 4.6e-05 23.2 0.1 4.6e-05 23.2 0.1 2.2 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain DUF5336 PF17270.2 CDJ49898.1 - 0.0027 17.4 4.2 0.0027 17.4 4.2 15.3 12 5 1 13 13 13 1 Family of unknown function (DUF5336) DUF2722 PF10846.8 CDJ49898.1 - 0.0034 16.4 19.0 0.0034 16.4 19.0 15.3 4 3 8 14 14 14 1 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ49898.1 - 0.0098 15.9 8.5 0.0098 15.9 8.5 25.8 7 5 8 15 15 15 1 Unstructured region C-term to UIM in Ataxin3 RVP_2 PF08284.11 CDJ49899.1 - 1.2e-10 41.3 0.0 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 CDJ49899.1 - 1.9e-09 37.4 0.0 3.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ49899.1 - 2.2e-08 34.6 0.0 4.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ49899.1 - 9.7e-08 32.5 0.0 2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ49899.1 - 0.0018 18.5 0.0 0.005 17.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 CDJ49899.1 - 0.029 14.2 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Chromo PF00385.24 CDJ49900.1 - 4.1e-13 49.0 0.0 6.7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain fn3 PF00041.21 CDJ49900.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.5 1 1 0 1 1 1 0 Fibronectin type III domain TIP49 PF06068.13 CDJ49901.1 - 1e-114 383.4 0.2 1.2e-114 383.2 0.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA PF00004.29 CDJ49901.1 - 3.7e-06 27.4 0.3 0.0028 18.1 0.2 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ49901.1 - 0.0037 17.0 0.1 0.0097 15.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CDJ49901.1 - 0.035 14.1 0.1 0.08 12.9 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CDJ49901.1 - 0.083 12.5 3.3 0.085 12.4 0.6 2.1 1 1 1 2 2 2 0 AAA domain Raco_middle PF17651.1 CDJ49901.1 - 0.15 11.7 0.1 0.37 10.4 0.1 1.6 1 0 0 1 1 1 0 RACo middle region CD20 PF04103.15 CDJ49902.1 - 2.5e-05 24.4 0.1 2.5e-05 24.4 0.1 1.6 2 0 0 2 2 1 1 CD20-like family DUF2232 PF09991.9 CDJ49902.1 - 0.011 14.9 9.9 0.018 14.2 9.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) EOS1 PF12326.8 CDJ49902.1 - 0.062 13.2 0.2 0.058 13.3 0.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein EphA2_TM PF14575.6 CDJ49902.1 - 0.064 14.1 2.7 0.064 14.1 2.7 2.4 3 0 0 3 3 1 0 Ephrin type-A receptor 2 transmembrane domain eIF-3_zeta PF05091.12 CDJ49902.1 - 0.071 12.1 12.2 0.087 11.8 12.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MecA PF05389.12 CDJ49902.1 - 0.096 12.3 6.3 0.14 11.8 6.3 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) TMEM51 PF15345.6 CDJ49902.1 - 0.14 12.0 11.7 0.25 11.1 11.7 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1980 PF09323.10 CDJ49902.1 - 0.17 11.8 6.2 0.3 11.0 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DcuA_DcuB PF03605.14 CDJ49902.1 - 0.18 10.7 20.0 0.33 9.8 20.0 1.3 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter SID-1_RNA_chan PF13965.6 CDJ49902.1 - 0.2 10.1 1.7 0.23 9.8 1.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDHD PF02862.17 CDJ49902.1 - 0.44 10.7 11.1 0.71 10.0 11.1 1.4 1 0 0 1 1 1 0 DDHD domain Trp_oprn_chp PF09534.10 CDJ49902.1 - 0.5 10.1 46.7 0.036 13.9 30.2 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PigN PF04987.14 CDJ49902.1 - 0.72 8.7 2.2 0.86 8.4 2.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Ctr PF04145.15 CDJ49902.1 - 0.94 10.1 3.4 1.6 9.3 3.4 1.5 1 0 0 1 1 1 0 Ctr copper transporter family G0-G1_switch_2 PF15103.6 CDJ49902.1 - 0.95 9.9 8.3 3.7 8.0 6.9 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Connexin PF00029.19 CDJ49902.1 - 1.1 8.9 6.1 1.5 8.6 6.1 1.2 1 0 0 1 1 1 0 Connexin Septin PF00735.18 CDJ49902.1 - 1.1 8.4 6.9 7.5 5.7 4.9 2.1 2 0 0 2 2 2 0 Septin TCP PF03634.13 CDJ49902.1 - 1.3 9.5 14.5 2.4 8.7 14.5 1.4 1 0 0 1 1 1 0 TCP family transcription factor Presenilin PF01080.17 CDJ49902.1 - 1.8 7.3 14.7 2.5 6.8 14.7 1.3 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 CDJ49902.1 - 2.3 7.0 7.9 3 6.7 7.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) OATP PF03137.20 CDJ49902.1 - 4.2 5.5 7.2 6.9 4.8 7.2 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Orf78 PF06024.12 CDJ49902.1 - 5.3 7.4 7.1 10 6.5 7.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) SpoIIP PF07454.11 CDJ49902.1 - 5.5 6.4 13.6 8.2 5.8 13.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RIFIN PF02009.16 CDJ49902.1 - 9.8 6.0 21.5 1.7 8.5 15.5 2.0 2 0 0 2 2 2 0 Rifin RVP_2 PF08284.11 CDJ49903.1 - 3.5e-09 36.5 0.0 6.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ49903.1 - 9.3e-08 32.6 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ49903.1 - 8.1e-07 29.5 0.0 1.6e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ49903.1 - 0.0014 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ49903.1 - 0.011 16.1 0.0 0.041 14.2 0.0 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease AMP-binding PF00501.28 CDJ49906.1 - 9e-47 159.6 0.0 3.1e-30 105.1 0.0 3.6 1 1 1 2 2 2 2 AMP-binding enzyme Peptidase_C54 PF03416.19 CDJ49908.1 - 0.00029 20.3 0.4 0.00058 19.4 0.4 1.4 1 0 0 1 1 1 1 Peptidase family C54 Zip PF02535.22 CDJ49909.1 - 0.00016 21.0 7.5 0.00023 20.5 7.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 CDJ49909.1 - 0.0067 14.9 5.6 0.013 14.0 5.6 1.4 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 O-antigen_lig PF13425.6 CDJ49909.1 - 0.016 14.0 6.8 0.023 13.5 6.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RR_TM4-6 PF06459.12 CDJ49909.1 - 0.018 14.9 23.6 0.031 14.1 23.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ49909.1 - 0.065 12.2 7.7 0.1 11.5 7.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 CDJ49909.1 - 0.24 11.4 18.9 0.4 10.7 18.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HCO3_cotransp PF00955.21 CDJ49909.1 - 0.6 8.9 7.5 0.86 8.3 7.5 1.2 1 0 0 1 1 1 0 HCO3- transporter family Endostatin PF06482.11 CDJ49909.1 - 1.9 7.9 24.9 3 7.2 24.9 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Peptidase_S49_N PF08496.10 CDJ49909.1 - 3 7.9 25.0 16 5.5 25.0 2.0 1 1 0 1 1 1 0 Peptidase family S49 N-terminal GAGA_bind PF06217.12 CDJ49909.1 - 3.7 7.8 21.5 5.5 7.2 21.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Rtf2 PF04641.12 CDJ49909.1 - 6.5 6.0 20.8 13 5.0 20.8 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4045 PF13254.6 CDJ49909.1 - 7.2 6.1 27.5 11 5.6 27.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SLC12 PF03522.15 CDJ49909.1 - 8 5.4 27.9 12 4.8 27.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Laminin_G_3 PF13385.6 CDJ49910.1 - 6.5e-15 55.6 0.0 1.3e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 CDJ49910.1 - 0.00014 22.5 0.0 0.00045 20.8 0.0 1.9 1 1 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 CDJ49910.1 - 0.00058 20.1 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain DNA_pol_A PF00476.20 CDJ49911.1 - 1.9e-10 40.4 0.0 3.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family A Sec20 PF03908.13 CDJ49912.1 - 0.007 16.3 0.8 0.007 16.3 0.8 2.3 1 1 2 3 3 3 1 Sec20 AAA_26 PF13500.6 CDJ49912.1 - 0.1 12.4 3.3 0.16 11.8 3.3 1.3 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 CDJ49912.1 - 0.94 9.0 20.3 1.2 8.6 20.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3488 PF11992.8 CDJ49912.1 - 1.7 7.5 9.7 2.8 6.8 9.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3488) PAT1 PF09770.9 CDJ49912.1 - 2.6 6.2 32.0 3.5 5.8 32.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MMR1 PF08505.10 CDJ49912.1 - 4 7.6 19.6 7.3 6.8 19.6 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein ALMT PF11744.8 CDJ49912.1 - 8.8 5.0 10.6 12 4.6 10.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Dpy-30 PF05186.13 CDJ49913.1 - 6.3e-14 51.4 0.6 9.1e-14 50.9 0.6 1.2 1 0 0 1 1 1 1 Dpy-30 motif UTP15_C PF09384.10 CDJ49914.1 - 2.9e-13 49.7 0.2 2.9e-13 49.7 0.2 2.4 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.32 CDJ49914.1 - 0.0092 16.8 3.1 0.14 13.0 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Cys_rich_VLP PF14194.6 CDJ49914.1 - 0.088 12.9 0.2 0.36 11.0 0.2 2.0 1 0 0 1 1 1 0 Cysteine-rich VLP TSLP PF15216.6 CDJ49915.1 - 0.16 12.2 1.0 0.35 11.2 1.0 1.5 1 0 0 1 1 1 0 Thymic stromal lymphopoietin MYT1 PF08474.11 CDJ49915.1 - 3.8 7.4 28.2 0.04 13.9 14.0 2.2 1 1 1 2 2 2 0 Myelin transcription factor 1 Ras PF00071.22 CDJ49916.1 - 8.7e-08 31.9 0.0 0.00048 19.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CDJ49916.1 - 0.012 15.8 0.0 0.074 13.3 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CDJ49916.1 - 0.094 13.2 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 CDJ49916.1 - 0.096 13.1 0.0 0.24 11.8 0.0 1.7 1 1 1 2 2 2 0 RNA helicase DUF547 PF04784.14 CDJ49917.1 - 5.7e-07 29.6 0.0 5.7e-07 29.6 0.0 3.7 3 2 1 4 4 4 2 Protein of unknown function, DUF547 DUF2722 PF10846.8 CDJ49917.1 - 0.00036 19.6 5.2 0.00036 19.6 5.2 4.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) TPR_19 PF14559.6 CDJ49918.1 - 9.1e-06 26.1 17.3 0.083 13.4 4.0 4.5 2 1 1 3 3 3 3 Tetratricopeptide repeat SPX PF03105.19 CDJ49918.1 - 8.7e-05 22.6 2.6 8.7e-05 22.6 2.6 1.9 2 0 0 2 2 2 1 SPX domain TPR_11 PF13414.6 CDJ49918.1 - 0.0023 17.6 2.9 0.27 11.0 0.6 2.7 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.6 CDJ49918.1 - 0.018 15.4 2.5 1 9.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Macoilin PF09726.9 CDJ49918.1 - 0.035 12.7 9.1 0.062 11.8 9.1 1.3 1 0 0 1 1 1 0 Macoilin family TPR_14 PF13428.6 CDJ49918.1 - 0.038 14.8 31.3 0.045 14.6 3.4 5.5 4 1 1 5 5 3 0 Tetratricopeptide repeat DUF4667 PF15700.5 CDJ49918.1 - 0.04 14.0 14.4 0.15 12.1 10.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) TPR_8 PF13181.6 CDJ49918.1 - 0.096 12.9 0.2 8.9 6.8 0.3 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ49918.1 - 0.13 12.1 2.2 5.1 7.1 0.2 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat SpoIIIAH PF12685.7 CDJ49918.1 - 0.18 11.6 3.9 0.7 9.7 3.9 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein Peptidase_S64 PF08192.11 CDJ49918.1 - 1.9 6.9 6.1 2.7 6.4 6.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 NPR3 PF03666.13 CDJ49918.1 - 5.5 5.7 8.1 9.2 4.9 8.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ49918.1 - 6.4 5.4 6.5 11 4.7 6.5 1.3 1 0 0 1 1 1 0 Presenilin DUF1967 PF09269.11 CDJ49921.1 - 0.022 14.7 0.3 0.057 13.4 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Hemocyanin_M PF00372.19 CDJ49921.1 - 0.096 11.9 0.3 0.15 11.3 0.3 1.2 1 0 0 1 1 1 0 Hemocyanin, copper containing domain RskA PF10099.9 CDJ49923.1 - 0.035 14.4 1.6 0.078 13.3 1.6 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Abhydrolase_5 PF12695.7 CDJ49923.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Insulin_TMD PF17870.1 CDJ49924.1 - 0.14 12.3 0.2 0.14 12.3 0.2 1.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Synaptobrevin PF00957.21 CDJ49927.1 - 4.9e-28 96.8 1.9 6.7e-28 96.3 1.9 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CDJ49927.1 - 4.6e-19 68.2 0.2 7.9e-19 67.5 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain MCU PF04678.13 CDJ49927.1 - 0.069 13.2 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Herpes_teg_N PF04843.12 CDJ49927.1 - 0.081 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region HHH_8 PF14716.6 CDJ49928.1 - 0.07 13.5 0.1 0.53 10.7 0.0 2.5 3 0 0 3 3 3 0 Helix-hairpin-helix domain Kazal_2 PF07648.15 CDJ49929.1 - 8.8e-08 32.2 2.4 4.8e-07 29.8 2.4 2.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CDJ49929.1 - 6.2e-05 22.9 0.5 0.0002 21.3 0.5 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain SR-25 PF10500.9 CDJ49929.1 - 0.00026 20.7 4.1 0.00026 20.7 4.1 6.3 5 1 0 6 6 6 2 Nuclear RNA-splicing-associated protein DUF2694 PF10904.8 CDJ49930.1 - 0.1 12.7 9.5 20 5.4 0.2 4.5 1 1 5 6 6 6 0 Protein of unknown function (DUF2694) FAM75 PF14650.6 CDJ49930.1 - 0.6 9.6 5.4 3.4 7.1 0.5 2.2 1 1 1 2 2 2 0 FAM75 family 5-FTHF_cyc-lig PF01812.20 CDJ49930.1 - 0.67 9.8 6.0 1 9.2 1.4 2.4 1 1 1 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family FliT PF05400.13 CDJ49930.1 - 9.8 7.1 21.4 2.9 8.8 3.1 3.9 2 1 2 4 4 4 0 Flagellar protein FliT TPPII_N PF12583.8 CDJ49931.1 - 1 9.9 14.4 3.4 8.2 14.4 1.9 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal RskA PF10099.9 CDJ49931.1 - 2.9 8.2 17.6 0.08 13.2 11.4 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SDA1 PF05285.12 CDJ49933.1 - 0.22 10.9 29.2 0.24 10.8 29.2 1.0 1 0 0 1 1 1 0 SDA1 Pex14_N PF04695.13 CDJ49933.1 - 0.46 11.1 11.0 0.6 10.8 11.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3915 PF13054.6 CDJ49933.1 - 0.87 9.6 17.9 0.72 9.8 4.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) DUF4614 PF15391.6 CDJ49933.1 - 1.3 9.0 15.9 1.7 8.6 15.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Dsh_C PF12316.8 CDJ49933.1 - 2.4 8.5 9.0 3 8.2 9.0 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Nop14 PF04147.12 CDJ49933.1 - 3 6.0 26.9 3.1 5.9 26.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDJ49933.1 - 5.1 5.3 24.9 5.4 5.2 24.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 CDJ49933.1 - 8.5 5.8 20.7 10 5.6 20.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF913 PF06025.12 CDJ49934.1 - 0.005 15.9 5.9 0.005 15.9 5.9 1.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) Med19 PF10278.9 CDJ49934.1 - 0.0084 16.1 7.0 0.0084 16.1 7.0 1.6 2 0 0 2 2 1 1 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.14 CDJ49934.1 - 0.013 13.8 15.0 0.026 12.8 15.0 1.4 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.7 CDJ49934.1 - 0.025 14.4 23.6 0.026 14.3 13.2 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein ALMT PF11744.8 CDJ49934.1 - 0.051 12.4 12.0 0.1 11.4 12.0 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter MMU163 PF17119.5 CDJ49934.1 - 0.2 10.8 4.7 0.5 9.5 4.7 1.7 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Zip PF02535.22 CDJ49934.1 - 0.29 10.3 8.1 0.57 9.4 8.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.16 CDJ49934.1 - 0.3 10.2 10.2 0.28 10.3 7.9 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Endostatin PF06482.11 CDJ49934.1 - 0.42 10.0 19.3 0.065 12.7 11.4 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Radical_SAM_N PF08497.10 CDJ49934.1 - 0.63 9.2 11.4 1.3 8.2 11.4 1.4 1 0 0 1 1 1 0 Radical SAM N-terminal NPR3 PF03666.13 CDJ49934.1 - 1.1 8.0 20.8 0.53 9.0 18.0 1.8 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Paf1 PF03985.13 CDJ49934.1 - 1.1 8.2 32.9 0.039 13.0 26.6 1.7 2 0 0 2 2 2 0 Paf1 XRN_M PF17846.1 CDJ49934.1 - 2.9 6.7 15.8 2 7.3 13.2 1.9 2 0 0 2 2 2 0 Xrn1 helical domain SpoIIP PF07454.11 CDJ49934.1 - 3.1 7.2 25.4 1.3 8.4 21.6 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Membralin PF09746.9 CDJ49934.1 - 3.1 6.7 10.0 6.7 5.6 10.0 1.5 1 0 0 1 1 1 0 Tumour-associated protein HCO3_cotransp PF00955.21 CDJ49934.1 - 3.9 6.2 5.6 7.5 5.2 5.6 1.4 1 0 0 1 1 1 0 HCO3- transporter family Cellulose_synt PF03552.14 CDJ49934.1 - 4.1 5.8 5.6 5.6 5.3 5.6 1.1 1 0 0 1 1 1 0 Cellulose synthase Dicty_REP PF05086.12 CDJ49934.1 - 4.5 5.1 11.5 6.2 4.7 11.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Presenilin PF01080.17 CDJ49934.1 - 5.2 5.7 34.6 0.65 8.7 27.1 2.2 2 0 0 2 2 2 0 Presenilin Afi1 PF07792.12 CDJ49934.1 - 6.6 7.2 23.7 3.9 8.0 19.9 2.4 3 0 0 3 3 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PAT1 PF09770.9 CDJ49934.1 - 7.9 4.6 48.6 0.16 10.2 30.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PIEZO PF15917.5 CDJ49937.1 - 0.054 13.0 14.6 0.062 12.8 14.6 1.0 1 0 0 1 1 1 0 Piezo 2_5_RNA_ligase2 PF13563.6 CDJ49937.1 - 0.065 13.1 3.5 0.071 13.0 3.5 1.0 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Suf PF05843.14 CDJ49937.1 - 3.1 7.7 15.0 3.8 7.4 15.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1454 PF07305.12 CDJ49937.1 - 3.6 7.0 10.1 4.3 6.7 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) TFIIA PF03153.13 CDJ49937.1 - 3.9 7.4 26.6 4.6 7.1 26.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gti1_Pac2 PF09729.9 CDJ49937.1 - 7.1 6.7 11.2 8.3 6.5 11.2 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family CLN3 PF02487.17 CDJ49937.1 - 7.7 5.4 8.0 8.5 5.3 8.0 1.0 1 0 0 1 1 1 0 CLN3 protein CCDC53 PF10152.9 CDJ49937.1 - 8.3 6.8 13.9 9.6 6.6 13.9 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RR_TM4-6 PF06459.12 CDJ49937.1 - 8.8 6.1 12.5 9.8 5.9 12.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ49937.1 - 9.6 4.9 15.5 11 4.7 15.5 1.0 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 CDJ49938.1 - 0.00078 19.8 4.5 0.00078 19.8 4.5 3.8 2 1 1 3 3 3 2 Anti-sigma-K factor rskA STAC2_u1 PF16664.5 CDJ49939.1 - 0.54 10.7 6.7 0.65 10.5 6.7 1.2 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 TFIIA PF03153.13 CDJ49940.1 - 0.002 18.2 36.4 0.0031 17.6 36.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ49940.1 - 0.017 14.6 8.6 0.025 14.0 8.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) V_ATPase_I PF01496.19 CDJ49940.1 - 0.057 11.3 8.6 0.071 11.0 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 CDJ49940.1 - 0.14 11.1 10.1 0.2 10.7 10.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF4667 PF15700.5 CDJ49940.1 - 0.19 11.8 24.5 0.48 10.5 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) AF-4 PF05110.13 CDJ49940.1 - 0.25 9.4 32.4 0.76 7.8 12.9 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Connexin PF00029.19 CDJ49940.1 - 0.3 10.8 6.6 0.49 10.1 6.6 1.4 1 0 0 1 1 1 0 Connexin EPL1 PF10513.9 CDJ49940.1 - 0.38 11.1 12.8 0.4 11.0 11.4 1.7 2 0 0 2 2 2 0 Enhancer of polycomb-like RIFIN PF02009.16 CDJ49940.1 - 0.52 10.2 7.5 0.038 13.9 2.3 1.6 2 0 0 2 2 2 0 Rifin eIF-3_zeta PF05091.12 CDJ49940.1 - 0.63 9.0 13.5 0.81 8.6 13.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) LMBR1 PF04791.16 CDJ49940.1 - 0.7 8.7 2.0 0.95 8.3 2.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein WDCP PF15390.6 CDJ49940.1 - 0.96 7.7 9.9 1.6 7.1 9.9 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Paf1 PF03985.13 CDJ49940.1 - 1.1 8.1 17.4 2 7.3 17.4 1.4 1 0 0 1 1 1 0 Paf1 MDM10 PF12519.8 CDJ49940.1 - 1.5 7.6 9.0 2.4 6.9 9.0 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Tim54 PF11711.8 CDJ49940.1 - 1.7 7.4 12.6 0.082 11.7 7.1 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Hid1 PF12722.7 CDJ49940.1 - 2.1 6.4 15.0 3.2 5.8 15.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CSG2 PF16965.5 CDJ49940.1 - 3.8 6.4 4.9 5.9 5.7 4.9 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator PAT1 PF09770.9 CDJ49940.1 - 4.1 5.6 23.0 5.8 5.1 23.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CLN3 PF02487.17 CDJ49940.1 - 6.9 5.6 9.4 13 4.7 9.4 1.4 1 0 0 1 1 1 0 CLN3 protein DUF4746 PF15928.5 CDJ49940.1 - 7.4 5.9 10.6 10 5.4 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PRA1 PF03208.19 CDJ49941.1 - 1.1e-15 57.5 0.0 2.7e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 PRA1 family protein Androgen_recep PF02166.16 CDJ49941.1 - 0.0062 15.4 9.3 0.0062 15.4 9.3 6.3 3 1 2 6 6 6 1 Androgen receptor Meis_PKNOX_N PF16493.5 CDJ49941.1 - 0.75 10.2 3.5 0.28 11.5 0.2 2.1 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 O-antigen_lig PF13425.6 CDJ49941.1 - 0.79 8.4 2.6 1.2 7.8 2.6 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein KH_1 PF00013.29 CDJ49942.1 - 3.5e-18 65.2 1.7 7.8e-07 28.8 0.0 5.9 5 0 0 5 5 5 5 KH domain BMC PF00936.19 CDJ49942.1 - 0.0049 16.8 2.4 0.29 11.2 0.0 4.2 4 1 0 4 4 4 1 BMC domain KH_2 PF07650.17 CDJ49942.1 - 0.3 10.9 9.6 2.7 7.9 0.0 3.8 4 0 0 4 4 4 0 KH domain Methyltransf_32 PF13679.6 CDJ49942.1 - 5.6 6.9 9.8 2.9 7.9 6.2 2.5 2 1 0 2 2 2 0 Methyltransferase domain Cnn_1N PF07989.11 CDJ49943.1 - 0.0031 17.6 1.4 0.0031 17.6 1.4 4.2 2 2 1 3 3 3 1 Centrosomin N-terminal motif 1 HALZ PF02183.18 CDJ49943.1 - 0.36 11.1 0.1 0.36 11.1 0.1 4.3 4 1 0 4 4 4 0 Homeobox associated leucine zipper Lebercilin PF15619.6 CDJ49943.1 - 0.44 10.2 40.8 0.98 9.0 20.6 3.6 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF948 PF06103.11 CDJ49943.1 - 0.45 10.8 7.7 7.7 6.8 0.4 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) FliD_C PF07195.12 CDJ49943.1 - 1.8 7.9 7.6 3 7.2 1.3 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Ntox28 PF15605.6 CDJ49943.1 - 5.1 7.4 10.6 0.99 9.7 0.6 3.2 2 1 0 2 2 2 0 Bacterial toxin 28 TssC PF17541.2 CDJ49943.1 - 6.7 5.4 7.3 0.84 8.4 3.0 1.6 2 0 0 2 2 2 0 Type VI secretion system, TssC, VipB D5_N PF08706.11 CDJ49943.1 - 8.8 6.6 6.7 3.1 8.1 2.5 2.3 2 0 0 2 2 2 0 D5 N terminal like CTP_transf_like PF01467.26 CDJ49944.1 - 9.1e-32 110.2 0.2 1.7e-31 109.3 0.2 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like Pribosyltran PF00156.27 CDJ49945.1 - 6e-23 81.1 0.0 7.7e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 CDJ49945.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Vma12 PF11712.8 CDJ49946.1 - 1.1e-09 38.4 0.0 1.1e-09 38.4 0.0 2.6 2 1 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase UPF0139 PF03669.13 CDJ49946.1 - 0.23 11.3 1.7 0.56 10.1 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0139) SUIM_assoc PF16619.5 CDJ49946.1 - 0.75 9.9 34.8 0.16 12.0 13.5 3.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1387 PF07139.11 CDJ49946.1 - 0.77 9.4 18.7 1.2 8.8 18.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Apt1 PF10351.9 CDJ49946.1 - 3.1 6.6 9.9 3.8 6.2 9.9 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain BSP_II PF05432.11 CDJ49946.1 - 3.9 7.1 22.8 5.4 6.6 22.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ndc1_Nup PF09531.10 CDJ49946.1 - 5.8 5.5 15.3 9.6 4.8 15.3 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.14 CDJ49947.1 - 0.015 13.6 25.9 0.018 13.3 25.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RIFIN PF02009.16 CDJ49947.1 - 0.25 11.2 27.8 0.33 10.8 27.8 1.3 1 0 0 1 1 1 0 Rifin DUF4746 PF15928.5 CDJ49947.1 - 0.54 9.6 16.5 0.84 9.0 16.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2126 PF09899.9 CDJ49947.1 - 1 7.4 17.2 1.5 6.8 17.2 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) LMBR1 PF04791.16 CDJ49947.1 - 1.2 7.9 10.6 1.3 7.9 10.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Cellulose_synt PF03552.14 CDJ49947.1 - 3.2 6.1 10.2 3.9 5.8 10.2 1.1 1 0 0 1 1 1 0 Cellulose synthase SR-25 PF10500.9 CDJ49947.1 - 5.2 6.6 51.5 4.3 6.9 21.5 2.5 1 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein MelC1 PF06236.11 CDJ49947.1 - 5.8 7.0 35.1 4.5 7.4 11.7 2.5 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 PAT1 PF09770.9 CDJ49947.1 - 9.3 4.4 52.7 11 4.1 52.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RIFIN PF02009.16 CDJ49948.1 - 5.2 6.9 4.8 5.7 6.7 4.8 1.0 1 0 0 1 1 1 0 Rifin PA26 PF04636.13 CDJ49950.1 - 0.037 12.9 1.7 0.037 12.9 1.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SR-25 PF10500.9 CDJ49950.1 - 0.042 13.5 11.4 0.06 12.9 11.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ49950.1 - 0.24 11.3 13.1 0.3 11.0 13.1 1.1 1 0 0 1 1 1 0 SPX domain LAP1C PF05609.12 CDJ49950.1 - 0.34 10.0 11.8 0.39 9.8 11.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TFIIA PF03153.13 CDJ49950.1 - 1 9.3 28.5 1.3 8.9 28.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ49950.1 - 1.2 8.9 7.3 1.5 8.6 7.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDV3 PF15359.6 CDJ49950.1 - 7 7.1 16.2 2 8.9 13.1 1.6 1 1 1 2 2 2 0 Carnitine deficiency-associated protein 3 Connexin PF00029.19 CDJ49950.1 - 9.5 5.9 7.6 14 5.3 7.6 1.4 1 1 0 1 1 1 0 Connexin RRM_1 PF00076.22 CDJ49951.1 - 2.7e-10 39.9 0.0 4.5e-09 36.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CDJ49951.1 - 8.4e-06 25.7 1.9 8.4e-06 25.7 1.9 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 CDJ49951.1 - 4e-05 23.4 0.8 8.2e-05 22.4 0.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Exonuc_VII_L PF02601.15 CDJ49951.1 - 0.00053 19.6 9.2 0.00053 19.6 9.2 4.0 3 2 1 4 4 4 1 Exonuclease VII, large subunit zf-CCCH_4 PF18044.1 CDJ49951.1 - 0.0022 17.7 1.0 0.0041 16.9 1.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CDJ49951.1 - 0.0037 17.9 0.0 0.0037 17.9 0.0 4.2 3 1 0 3 3 3 1 Torus domain Hist_deacetyl PF00850.19 CDJ49951.1 - 0.51 9.8 4.4 1.7 8.0 4.4 1.9 1 0 0 1 1 1 0 Histone deacetylase domain PI3K_1B_p101 PF10486.9 CDJ49951.1 - 7.8 4.1 22.0 16 3.1 22.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_delta_4 PF04081.13 CDJ49952.1 - 1.4e-17 64.3 0.0 2.1e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Tex_N PF09371.10 CDJ49952.1 - 0.55 9.9 1.5 29 4.3 0.0 2.1 2 0 0 2 2 2 0 Tex-like protein N-terminal domain Shadoo PF14999.6 CDJ49952.1 - 2.6 8.1 12.0 1.1 9.3 9.7 1.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective PepSY_2 PF13670.6 CDJ49952.1 - 6.4 6.9 9.8 14 5.8 9.8 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Herpes_capsid PF06112.11 CDJ49953.1 - 0.0081 16.2 10.3 0.013 15.6 10.3 1.3 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein Lin-8 PF03353.15 CDJ49953.1 - 0.0083 15.7 26.9 0.013 15.1 26.9 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist DUF5427 PF10310.9 CDJ49953.1 - 0.3 10.0 23.0 0.43 9.5 23.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF572 PF04502.13 CDJ49953.1 - 0.4 10.2 21.0 0.58 9.7 21.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Exonuc_VII_L PF02601.15 CDJ49953.1 - 2.5 7.6 19.7 3.2 7.2 19.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.9 CDJ49953.1 - 2.7 6.1 33.4 4 5.6 33.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Clr2 PF10383.9 CDJ49953.1 - 8.2 7.2 13.4 3.6 8.3 10.0 2.0 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 Pkinase PF00069.25 CDJ49954.1 - 3e-29 102.2 0.4 2.5e-16 59.8 0.0 4.1 3 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ49954.1 - 6e-12 45.4 0.9 2e-07 30.6 0.0 3.7 4 0 0 4 4 4 2 Protein tyrosine kinase DUF2722 PF10846.8 CDJ49954.1 - 0.0025 16.8 11.9 0.0025 16.8 11.9 4.7 3 1 0 4 4 4 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ49954.1 - 0.0095 16.0 11.3 0.0095 16.0 11.3 5.1 3 1 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit Kinase-like PF14531.6 CDJ49954.1 - 0.012 15.0 0.0 0.012 15.0 0.0 2.7 3 0 0 3 3 3 0 Kinase-like Dpy19 PF10034.9 CDJ49954.1 - 0.017 13.3 0.0 0.017 13.3 0.0 1.8 2 0 0 2 2 2 0 Q-cell neuroblast polarisation AfaD PF05775.12 CDJ49954.1 - 0.057 13.9 0.2 0.18 12.2 0.2 1.8 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein MecA PF05389.12 CDJ49954.1 - 8.4 5.9 15.8 0.51 9.9 0.2 3.0 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) DUF3682 PF12446.8 CDJ49955.1 - 0.01 16.3 1.6 0.01 16.3 1.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3682) CDK2AP PF09806.9 CDJ49955.1 - 0.25 11.4 12.7 0.26 11.3 12.1 1.2 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2076 PF09849.9 CDJ49955.1 - 0.45 10.5 29.5 0.71 9.9 17.6 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Presenilin PF01080.17 CDJ49955.1 - 1.1 8.0 5.0 1.4 7.6 5.0 1.2 1 0 0 1 1 1 0 Presenilin SAGA-Tad1 PF12767.7 CDJ49955.1 - 1.3 8.8 7.1 1.7 8.3 7.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Ndc1_Nup PF09531.10 CDJ49955.1 - 7.4 5.1 12.7 8.6 4.9 12.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCSAP PF15748.5 CDJ49956.1 - 0.097 12.8 32.2 0.14 12.3 32.2 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated V_ATPase_I PF01496.19 CDJ49956.1 - 0.15 9.9 16.4 0.15 9.9 16.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phe_ZIP PF08916.11 CDJ49956.1 - 0.21 12.3 6.7 0.62 10.8 2.2 2.5 2 0 0 2 2 2 0 Phenylalanine zipper TFIIA PF03153.13 CDJ49956.1 - 0.37 10.7 52.4 0.47 10.4 52.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ49956.1 - 0.93 7.5 40.4 1.1 7.2 40.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TerD PF02342.18 CDJ49957.1 - 9e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 TerD domain DEAD PF00270.29 CDJ49958.1 - 2.3e-32 112.2 0.0 3.8e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ49958.1 - 3.4e-27 95.0 0.1 4.2e-26 91.5 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ49958.1 - 0.062 13.3 0.0 0.44 10.5 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Proteasome PF00227.26 CDJ49959.1 - 1.6e-58 197.3 0.0 2.1e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ49959.1 - 1.6e-09 37.2 0.0 1.6e-09 37.2 0.0 2.4 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Med3 PF11593.8 CDJ49960.1 - 1.4 8.0 11.2 2.6 7.1 11.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PP2C PF00481.21 CDJ49962.1 - 1.7e-37 129.4 0.0 1.7e-37 129.4 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ49962.1 - 7e-05 22.6 0.0 7e-05 22.6 0.0 3.6 3 2 0 3 3 3 1 Protein phosphatase 2C Zip PF02535.22 CDJ49962.1 - 2.1 7.5 9.4 3.2 6.9 9.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter TMEM51 PF15345.6 CDJ49962.1 - 2.4 7.9 21.5 6.9 6.4 21.5 1.8 1 0 0 1 1 1 0 Transmembrane protein 51 Otopetrin PF03189.13 CDJ49962.1 - 4.6 6.0 4.5 5.6 5.7 4.5 1.2 1 0 0 1 1 1 0 Otopetrin Sin_N PF04801.13 CDJ49962.1 - 9 5.4 30.2 17 4.5 30.2 1.4 1 0 0 1 1 1 0 Sin-like protein conserved region Thioredoxin PF00085.20 CDJ49963.1 - 4.3e-05 23.5 0.0 0.00028 20.8 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin GHMP_kinases_N PF00288.26 CDJ49963.1 - 0.053 13.8 0.6 0.053 13.8 0.6 3.5 2 1 0 2 2 2 0 GHMP kinases N terminal domain SID-1_RNA_chan PF13965.6 CDJ49963.1 - 1 7.7 3.3 1.4 7.3 3.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LMBR1 PF04791.16 CDJ49963.1 - 1.4 7.8 9.8 1.9 7.3 9.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3295 PF11702.8 CDJ49963.1 - 1.7 7.9 23.5 2.3 7.5 23.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) SnAPC_2_like PF11035.8 CDJ49963.1 - 1.9 8.5 32.4 3 7.9 32.4 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF3340 PF11818.8 CDJ49963.1 - 5 7.3 20.9 1.5 8.9 17.5 1.8 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Spt20 PF12090.8 CDJ49964.1 - 0.45 10.1 27.3 0.48 10.0 27.3 1.1 1 0 0 1 1 1 0 Spt20 family Bud13 PF09736.9 CDJ49964.1 - 0.47 10.8 15.3 0.51 10.7 15.3 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex PEX11 PF05648.14 CDJ49964.1 - 1.1 8.7 5.5 1.3 8.5 5.5 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF4834 PF16118.5 CDJ49964.1 - 1.5 9.8 13.2 2 9.5 13.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3408 PF11888.8 CDJ49964.1 - 1.8 8.7 11.6 1.9 8.6 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) FAM176 PF14851.6 CDJ49964.1 - 2.7 7.7 7.3 3.2 7.4 7.3 1.2 1 0 0 1 1 1 0 FAM176 family DUF4746 PF15928.5 CDJ49964.1 - 6.1 6.2 8.5 5.6 6.3 8.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Sec62 PF03839.16 CDJ49964.1 - 9.8 5.6 6.9 10 5.5 6.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 AP2 PF00847.20 CDJ49965.1 - 0.00021 21.4 1.8 0.00049 20.3 1.8 1.7 1 0 0 1 1 1 1 AP2 domain Peptidase_S8 PF00082.22 CDJ49966.1 - 4.3e-23 82.0 0.5 1.1e-17 64.2 0.0 2.2 1 1 1 2 2 2 2 Subtilase family PrmA PF06325.13 CDJ49967.1 - 0.012 15.1 0.0 0.065 12.6 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 CDJ49967.1 - 0.052 12.7 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.20 CDJ49967.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Macoilin PF09726.9 CDJ49967.1 - 1.1 7.7 4.0 1.5 7.3 4.0 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ49967.1 - 3.3 6.5 4.6 4.4 6.1 4.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Serpin PF00079.20 CDJ49968.1 - 1e-77 262.0 0.6 1.2e-77 261.7 0.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Peptidase_M28 PF04389.17 CDJ49969.1 - 1.9e-06 27.7 0.0 4.1e-06 26.6 0.0 1.6 1 1 1 2 2 2 1 Peptidase family M28 IL2 PF00715.17 CDJ49969.1 - 0.051 13.5 0.1 8 6.4 0.0 2.6 2 0 0 2 2 2 0 Interleukin 2 Nicastrin PF05450.15 CDJ49969.1 - 0.051 13.0 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Nicastrin KCNQ2_u3 PF16642.5 CDJ49970.1 - 0.14 13.2 0.3 0.14 13.2 0.3 1.9 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Methyltransf_32 PF13679.6 CDJ49970.1 - 0.27 11.2 4.1 3.2 7.7 4.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain RskA PF10099.9 CDJ49971.1 - 0.0039 17.5 13.3 0.0039 17.5 13.3 10.5 2 1 4 6 6 6 2 Anti-sigma-K factor rskA DUF1682 PF07946.14 CDJ49972.1 - 0.11 11.7 0.6 0.13 11.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Spt20 PF12090.8 CDJ49973.1 - 0.065 12.8 45.6 0.11 12.0 18.5 2.7 3 0 0 3 3 3 0 Spt20 family PPP4R2 PF09184.11 CDJ49973.1 - 0.15 11.6 10.5 0.22 11.1 10.5 1.1 1 0 0 1 1 1 0 PPP4R2 DUF4667 PF15700.5 CDJ49973.1 - 0.19 11.8 18.5 0.78 9.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) PAT1 PF09770.9 CDJ49973.1 - 0.97 7.6 27.4 1.2 7.3 27.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2126 PF09899.9 CDJ49973.1 - 0.99 7.4 6.4 1.4 6.9 6.4 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Serinc PF03348.15 CDJ49973.1 - 1.3 7.9 4.1 1.9 7.3 4.1 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) V_ATPase_I PF01496.19 CDJ49973.1 - 2.7 5.8 9.1 4.2 5.2 9.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4820 PF16091.5 CDJ49973.1 - 4.4 6.6 15.7 0.81 9.0 11.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF2722 PF10846.8 CDJ49973.1 - 8.8 5.1 43.7 0.4 9.6 16.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) CAF1 PF04857.20 CDJ49974.1 - 0.79 8.8 14.2 0.96 8.6 14.2 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Presenilin PF01080.17 CDJ49974.1 - 1.5 7.5 21.1 1.6 7.4 21.1 1.1 1 0 0 1 1 1 0 Presenilin Vac7 PF12751.7 CDJ49974.1 - 3.4 7.0 13.4 3.9 6.8 13.4 1.0 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 tRNA_synt_1c_R2 PF04557.15 CDJ49974.1 - 6.3 7.8 15.0 5.3 8.0 2.8 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 RNA_pol_Rbc25 PF08292.12 CDJ49974.1 - 7.9 6.7 15.3 2.5 8.4 1.8 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 PP2C PF00481.21 CDJ49975.1 - 3.5e-40 138.3 0.1 3.5e-40 138.3 0.1 2.7 2 0 0 2 2 2 1 Protein phosphatase 2C SR-25 PF10500.9 CDJ49975.1 - 0.00047 19.8 16.0 0.00047 19.8 16.0 10.0 9 2 2 11 11 11 3 Nuclear RNA-splicing-associated protein SARAF PF06682.12 CDJ49975.1 - 0.00051 19.8 16.8 0.00051 19.8 16.8 9.5 6 4 3 9 9 9 1 SOCE-associated regulatory factor of calcium homoeostasis SAP18 PF06487.12 CDJ49976.1 - 3.9e-28 98.4 0.0 3.9e-28 98.4 0.0 5.5 4 3 0 4 4 4 1 Sin3 associated polypeptide p18 (SAP18) Herpes_UL74 PF07982.12 CDJ49976.1 - 1.6 7.6 3.1 2.7 6.8 3.1 1.3 1 0 0 1 1 1 0 Herpes UL74 glycoproteins SUIM_assoc PF16619.5 CDJ49977.1 - 0.02 14.9 1.0 0.062 13.4 0.8 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ49977.1 - 3.4 7.6 5.8 4 7.3 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Secretin_N_2 PF07655.13 CDJ49978.1 - 0.027 15.0 12.4 0.027 15.0 12.4 3.0 3 0 0 3 3 3 0 Secretin N-terminal domain AF-4 PF05110.13 CDJ49978.1 - 0.1 10.7 40.3 0.18 9.9 40.3 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TFIIA PF03153.13 CDJ49978.1 - 2.9 7.8 35.1 4.1 7.3 35.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_4 PF13637.6 CDJ49979.1 - 7.9e-09 35.9 0.0 0.00098 19.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ49979.1 - 4.7e-08 33.5 3.4 0.0026 18.3 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ49979.1 - 1.2e-07 31.4 0.1 0.75 10.5 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CDJ49979.1 - 2.6e-06 27.6 0.0 0.18 12.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CDJ49979.1 - 0.00021 21.5 0.0 0.0022 18.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Trp_oprn_chp PF09534.10 CDJ49979.1 - 0.013 15.3 11.7 0.013 15.3 11.7 4.8 5 2 0 5 5 5 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF898 PF05987.13 CDJ49979.1 - 0.41 9.7 3.4 0.79 8.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Dapper PF15268.6 CDJ49979.1 - 0.97 8.2 67.9 0.1 11.5 32.7 2.2 2 0 0 2 2 2 0 Dapper PAT1 PF09770.9 CDJ49979.1 - 1.7 6.8 94.1 0.69 8.1 50.1 2.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF2722 PF10846.8 CDJ49981.1 - 3.5e-05 22.9 26.0 0.0034 16.4 10.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ49981.1 - 0.00013 21.1 36.2 0.00017 20.7 5.6 2.3 2 0 0 2 2 2 2 Transcriptional activator LAG-3 SUIM_assoc PF16619.5 CDJ49981.1 - 0.018 15.1 7.4 0.018 15.1 7.4 4.4 3 1 0 3 3 2 0 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 CDJ49981.1 - 0.019 15.4 7.7 0.27 11.6 1.3 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Spt20 PF12090.8 CDJ49981.1 - 0.023 14.3 39.3 0.13 11.9 9.3 2.2 2 0 0 2 2 2 0 Spt20 family Astro_capsid_N PF03115.14 CDJ49981.1 - 0.024 13.3 0.6 0.024 13.3 0.6 1.4 2 0 0 2 2 1 0 Astrovirus capsid protein precursor DUF572 PF04502.13 CDJ49981.1 - 0.037 13.6 7.0 0.13 11.8 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Med15 PF09606.10 CDJ49981.1 - 0.066 11.9 28.1 0.4 9.3 6.6 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal TERB2 PF15101.6 CDJ49981.1 - 0.25 11.4 13.9 1.9 8.5 1.4 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 EIIBC-GUT_N PF03612.14 CDJ49981.1 - 0.65 9.7 10.5 3.1 7.5 0.3 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus BAF1_ABF1 PF04684.13 CDJ49981.1 - 0.75 8.8 8.1 0.91 8.5 1.0 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor CPSF100_C PF13299.6 CDJ49981.1 - 0.89 9.7 7.0 6.5 6.9 2.4 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RLL PF10036.9 CDJ49981.1 - 1.5 8.6 13.8 1.1 9.0 0.4 2.1 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein PIG-U PF06728.13 CDJ49981.1 - 1.8 7.5 3.7 0.93 8.5 0.1 1.9 1 1 1 3 3 3 0 GPI transamidase subunit PIG-U Plasmodium_Vir PF05795.11 CDJ49981.1 - 2.4 7.5 5.1 11 5.3 0.4 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein TYW3 PF02676.14 CDJ49981.1 - 2.7 7.3 7.2 1.1 8.6 0.8 2.3 2 1 0 2 2 2 0 Methyltransferase TYW3 TFIIA PF03153.13 CDJ49981.1 - 6.2 6.7 40.9 0.48 10.4 15.2 2.3 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Apc15p PF05841.11 CDJ49981.1 - 6.9 7.5 20.0 0.14 12.9 6.5 2.8 3 0 0 3 3 2 0 Apc15p protein Neur_chan_memb PF02932.16 CDJ49981.1 - 9.7 6.2 12.3 8.2 6.4 1.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RRM_1 PF00076.22 CDJ49982.1 - 5.7e-05 22.9 0.0 9.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lin-8 PF03353.15 CDJ49982.1 - 0.00014 21.5 13.9 0.00014 21.5 13.9 2.5 2 1 0 2 2 2 1 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ49982.1 - 0.02 14.5 38.5 0.064 12.9 10.1 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ49982.1 - 0.49 9.1 40.6 0.17 10.6 22.6 2.3 2 0 0 2 2 2 0 Presenilin Exonuc_VII_L PF02601.15 CDJ49982.1 - 1.6 8.2 28.3 3.3 7.2 12.1 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit TCP PF03634.13 CDJ49982.1 - 2.5 8.7 34.9 7.9 7.0 19.2 3.4 3 1 0 3 3 3 0 TCP family transcription factor SLC12 PF03522.15 CDJ49982.1 - 2.6 6.9 31.5 1.1 8.2 16.2 2.2 2 0 0 2 2 2 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ49982.1 - 5.7 6.9 30.5 4.1 7.4 8.5 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.13 CDJ49982.1 - 6.4 5.6 24.4 1.3 7.9 11.2 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Otopetrin PF03189.13 CDJ49982.1 - 7.4 5.3 11.1 0.52 9.1 2.6 2.1 2 0 0 2 2 2 0 Otopetrin SLATT_5 PF18160.1 CDJ49983.1 - 2.2 7.5 3.8 2.8 7.2 0.6 2.4 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 LSM PF01423.22 CDJ49984.1 - 1.3e-10 40.8 0.4 2.2e-10 40.0 0.4 1.4 1 1 0 1 1 1 1 LSM domain DAGK_cat PF00781.24 CDJ49985.1 - 7.6e-13 48.2 0.1 4.8e-12 45.6 0.1 2.0 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 CDJ49985.1 - 1.6e-09 38.3 0.0 2.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain Rotamase PF00639.21 CDJ49987.1 - 1.9e-11 44.8 0.2 2.8e-10 41.0 0.2 2.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain RskA PF10099.9 CDJ49987.1 - 0.00014 22.2 3.3 0.00021 21.7 3.3 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Rotamase_2 PF13145.6 CDJ49987.1 - 0.0086 16.9 1.1 0.055 14.3 0.3 2.5 2 1 0 2 2 2 1 PPIC-type PPIASE domain TFIIA PF03153.13 CDJ49987.1 - 0.029 14.4 9.5 0.037 14.0 9.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.11 CDJ49987.1 - 0.092 10.8 1.5 0.16 10.0 1.6 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Spt20 PF12090.8 CDJ49987.1 - 0.15 11.6 9.2 0.25 10.9 9.2 1.3 1 0 0 1 1 1 0 Spt20 family IMUP PF15761.5 CDJ49987.1 - 2.8 8.6 20.2 0.29 11.8 5.7 2.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein Lin-8 PF03353.15 CDJ49987.1 - 3.5 7.1 11.8 0.034 13.7 4.0 1.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF1645 PF07816.11 CDJ49987.1 - 6.9 7.2 10.7 3.3 8.2 4.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) BAF1_ABF1 PF04684.13 CDJ49988.1 - 0.0071 15.5 17.8 0.01 14.9 17.8 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DUF572 PF04502.13 CDJ49988.1 - 0.049 13.2 14.1 0.055 13.1 14.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.13 CDJ49988.1 - 0.059 13.4 41.3 0.073 13.1 41.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.8 CDJ49988.1 - 0.078 12.1 29.9 0.096 11.8 29.9 1.1 1 0 0 1 1 1 0 SprA-related family SR-25 PF10500.9 CDJ49988.1 - 0.14 11.8 17.1 0.18 11.4 17.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SART-1 PF03343.13 CDJ49988.1 - 0.15 10.6 17.8 0.19 10.3 17.8 1.1 1 0 0 1 1 1 0 SART-1 family SAGA-Tad1 PF12767.7 CDJ49988.1 - 0.22 11.2 14.4 0.28 10.9 14.4 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RIFIN PF02009.16 CDJ49988.1 - 0.34 10.8 11.2 0.43 10.4 11.2 1.0 1 0 0 1 1 1 0 Rifin V_ATPase_I PF01496.19 CDJ49988.1 - 0.71 7.7 17.7 0.88 7.4 17.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCSAP PF15748.5 CDJ49988.1 - 0.8 9.8 24.0 1.1 9.3 24.0 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FancD2 PF14631.6 CDJ49988.1 - 1.3 6.3 10.2 1.5 6.1 10.2 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease NPR3 PF03666.13 CDJ49988.1 - 1.8 7.3 16.9 2.1 7.1 16.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 CDJ49988.1 - 2.3 7.6 10.6 3.8 6.8 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SID-1_RNA_chan PF13965.6 CDJ49988.1 - 2.4 6.4 4.6 2.7 6.3 4.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 CDJ49988.1 - 2.6 7.0 17.9 3.2 6.7 17.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ49988.1 - 2.8 8.0 13.4 3.9 7.4 13.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ49988.1 - 3.5 6.6 9.4 4.2 6.3 9.4 1.2 1 0 0 1 1 1 0 CLN3 protein DUF913 PF06025.12 CDJ49988.1 - 3.9 6.4 9.9 4.7 6.1 9.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MCM_bind PF09739.9 CDJ49988.1 - 4.2 5.7 15.7 4.7 5.5 15.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor ECM1 PF05782.11 CDJ49988.1 - 4.5 6.1 24.7 5.8 5.7 24.7 1.0 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) MDM10 PF12519.8 CDJ49988.1 - 4.9 5.9 14.5 6.8 5.4 14.5 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Endostatin PF06482.11 CDJ49988.1 - 5.3 6.4 17.4 6.4 6.2 17.4 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin ALMT PF11744.8 CDJ49988.1 - 5.6 5.7 12.2 6.4 5.5 12.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF966 PF06136.13 CDJ49988.1 - 5.7 6.5 15.3 6.6 6.3 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDC45 PF02724.14 CDJ49988.1 - 5.8 5.1 16.3 7.1 4.8 16.3 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3_zeta PF05091.12 CDJ49988.1 - 7.8 5.4 22.8 13 4.7 22.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.22 CDJ49988.1 - 8.8 5.4 9.9 10 5.2 9.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3824 PF12868.7 CDJ49988.1 - 9 6.9 35.9 0.16 12.6 15.4 2.3 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) AKAP7_RIRII_bdg PF10470.9 CDJ49989.1 - 0.052 13.6 0.3 0.052 13.6 0.3 2.3 2 1 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Pkinase_fungal PF17667.1 CDJ49989.1 - 3.6 6.3 11.0 4.2 6.1 11.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase CDC45 PF02724.14 CDJ49989.1 - 6 5.0 17.5 7.2 4.8 17.5 1.0 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 CDJ49989.1 - 6.7 6.0 15.4 8.8 5.6 15.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2722 PF10846.8 CDJ49990.1 - 0.0057 15.7 6.6 0.0057 15.7 6.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) PEX11 PF05648.14 CDJ49990.1 - 0.024 14.1 2.3 0.07 12.6 0.6 2.0 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Activator_LAG-3 PF11498.8 CDJ49990.1 - 0.096 11.6 33.3 0.49 9.3 22.0 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF4834 PF16118.5 CDJ49990.1 - 0.12 13.4 5.0 0.85 10.6 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 CDJ49990.1 - 0.3 12.0 5.0 2.3 9.2 0.2 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2298 PF10060.9 CDJ49990.1 - 0.64 8.7 19.7 0.036 12.8 2.4 2.1 2 0 0 2 2 2 0 Uncharacterized membrane protein (DUF2298) FA_desaturase PF00487.24 CDJ49990.1 - 0.73 9.6 3.5 0.45 10.3 0.2 1.9 2 0 0 2 2 2 0 Fatty acid desaturase DUF3371 PF11851.8 CDJ49990.1 - 0.94 10.6 11.3 11 7.1 5.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) TFIIA PF03153.13 CDJ49990.1 - 1.2 9.0 38.3 1.3 8.9 23.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ49990.1 - 3.9 7.0 31.6 3.8 7.0 4.1 2.1 2 0 0 2 2 2 0 Spt20 family Suf PF05843.14 CDJ49990.1 - 6.5 6.6 16.0 1.3 9.0 8.4 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SpoIIE PF07228.12 CDJ49992.1 - 0.035 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Med15 PF09606.10 CDJ49992.1 - 0.38 9.4 13.9 0.44 9.2 13.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 CDJ49992.1 - 0.66 8.7 3.1 0.78 8.4 3.1 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CDJ49992.1 - 0.67 8.2 6.8 0.89 7.8 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.13 CDJ49992.1 - 1 10.0 8.7 0.21 12.2 2.7 2.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 CDJ49992.1 - 1.4 10.0 6.2 4.3 8.4 6.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ49992.1 - 1.5 8.4 19.8 0.15 11.6 15.6 1.4 2 0 0 2 2 2 0 Spt20 family Roughex PF06020.11 CDJ49992.1 - 5.8 5.9 11.2 1 8.4 7.7 1.5 2 0 0 2 2 2 0 Drosophila roughex protein DUF2967 PF11179.8 CDJ49992.1 - 9.3 4.2 8.6 19 3.2 8.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) PP2C PF00481.21 CDJ49993.1 - 9.2e-15 55.0 24.9 1.4e-10 41.3 6.9 3.8 3 1 1 4 4 4 3 Protein phosphatase 2C SR-25 PF10500.9 CDJ49993.1 - 4.5e-05 23.2 35.0 4.5e-05 23.2 35.0 5.2 4 2 0 5 5 5 2 Nuclear RNA-splicing-associated protein Filament_head PF04732.14 CDJ49993.1 - 5.4 8.0 58.7 5.8 7.8 18.6 3.6 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region Cyt_bd_oxida_II PF02322.15 CDJ49993.1 - 8.9 5.6 7.8 61 2.8 8.1 2.0 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II PIG-U PF06728.13 CDJ49995.1 - 3.6 6.5 6.3 19 4.1 0.1 3.9 4 0 0 4 4 4 0 GPI transamidase subunit PIG-U TMEM247 PF15444.6 CDJ49996.1 - 0.016 15.2 4.9 0.02 14.9 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 TFIIA PF03153.13 CDJ49996.1 - 0.036 14.1 16.6 0.044 13.8 16.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 CDJ49996.1 - 0.043 13.5 2.3 0.058 13.0 2.3 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis NPL PF17800.1 CDJ49996.1 - 0.098 13.2 5.4 0.14 12.7 4.9 1.6 1 1 0 1 1 1 0 Nucleoplasmin-like domain Roughex PF06020.11 CDJ49996.1 - 0.1 11.7 12.0 0.085 11.9 11.0 1.4 1 1 0 1 1 1 0 Drosophila roughex protein Secretin_N_2 PF07655.13 CDJ49996.1 - 0.1 13.1 3.5 0.76 10.4 0.8 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain DNA_pol_viral_C PF00336.18 CDJ49996.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain AAA_23 PF13476.6 CDJ49996.1 - 0.29 11.6 7.2 0.38 11.2 7.2 1.3 1 0 0 1 1 1 0 AAA domain P5-ATPase PF12409.8 CDJ49996.1 - 0.53 10.4 2.7 1 9.5 2.7 1.5 1 0 0 1 1 1 0 P5-type ATPase cation transporter Presenilin PF01080.17 CDJ49996.1 - 0.81 8.4 6.1 0.95 8.2 6.1 1.1 1 0 0 1 1 1 0 Presenilin PRP1_N PF06424.12 CDJ49996.1 - 0.99 9.8 11.4 1.4 9.3 11.0 1.4 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal ALMT PF11744.8 CDJ49996.1 - 2.6 6.8 8.7 3.1 6.5 8.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter P16-Arc PF04699.14 CDJ49996.1 - 3.1 8.3 13.2 5.4 7.5 7.0 2.3 1 1 1 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) CLN3 PF02487.17 CDJ49996.1 - 4.4 6.3 6.1 2.7 7.0 4.4 1.4 1 1 0 1 1 1 0 CLN3 protein LMBR1 PF04791.16 CDJ49997.1 - 0.03 13.3 7.9 0.036 13.0 7.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF572 PF04502.13 CDJ49997.1 - 0.96 9.0 16.1 1.4 8.5 16.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) WDCP PF15390.6 CDJ49997.1 - 2.6 6.3 14.2 3.3 6.0 14.2 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PAT1 PF09770.9 CDJ49997.1 - 2.9 6.1 40.1 4.2 5.5 40.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.19 CDJ49997.1 - 6.5 4.5 21.4 9.1 4.0 21.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family V-ATPase_H_N PF03224.14 CDJ49998.1 - 1.2e-14 54.4 0.0 6.3e-08 32.3 0.0 2.4 1 1 2 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 CDJ49998.1 - 0.00042 20.4 0.0 0.0034 17.5 0.0 2.3 2 0 0 2 2 2 1 V-ATPase subunit H Phostensin_N PF13916.6 CDJ49999.1 - 0.022 15.1 3.9 0.022 15.1 3.9 5.8 4 3 0 4 4 4 0 PP1-regulatory protein, Phostensin N-terminal Ribosomal_60s PF00428.19 CDJ49999.1 - 0.077 13.6 24.2 0.067 13.8 6.6 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4179 PF13786.6 CDJ49999.1 - 0.25 11.9 0.2 0.25 11.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Shadoo PF14999.6 CDJ49999.1 - 1.5 8.9 17.9 1.6 8.8 0.6 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Glutaredoxin PF00462.24 CDJ50001.1 - 1.9e-06 28.0 0.0 0.0042 17.3 0.0 2.9 2 1 0 2 2 2 2 Glutaredoxin Presenilin PF01080.17 CDJ50001.1 - 0.0016 17.3 17.8 0.0016 17.3 17.8 2.2 2 0 0 2 2 2 1 Presenilin CNDH2_C PF16858.5 CDJ50001.1 - 0.0019 18.1 16.2 0.0019 18.1 16.2 2.1 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CLN3 PF02487.17 CDJ50001.1 - 0.0047 16.0 10.3 0.0047 16.0 10.3 2.1 2 0 0 2 2 2 1 CLN3 protein SID-1_RNA_chan PF13965.6 CDJ50001.1 - 0.053 11.9 16.4 0.027 12.9 8.6 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 NPR3 PF03666.13 CDJ50001.1 - 0.068 11.9 27.4 0.039 12.8 14.7 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIP PF07454.11 CDJ50001.1 - 0.084 12.3 32.8 0.015 14.8 15.6 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) PPL5 PF18168.1 CDJ50001.1 - 0.12 11.6 19.9 0.062 12.6 8.1 2.1 2 0 0 2 2 2 0 Prim-pol family 5 MCM_bind PF09739.9 CDJ50001.1 - 0.15 10.5 31.9 0.021 13.3 15.4 2.1 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor Band_3_cyto PF07565.13 CDJ50001.1 - 0.26 11.1 32.1 0.13 12.0 13.3 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FAM76 PF16046.5 CDJ50001.1 - 0.28 10.5 30.8 0.23 10.8 17.2 2.2 2 0 0 2 2 2 0 FAM76 protein CCDC53 PF10152.9 CDJ50001.1 - 0.35 11.3 42.8 0.13 12.7 23.9 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Neur_chan_memb PF02932.16 CDJ50001.1 - 0.37 10.8 32.1 0.41 10.7 16.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 CDJ50001.1 - 0.42 10.3 26.1 2 8.1 3.1 2.3 2 0 0 2 2 2 0 Connexin RNA_pol_Rpc4 PF05132.14 CDJ50001.1 - 0.45 10.9 29.9 0.066 13.6 14.8 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Tim54 PF11711.8 CDJ50001.1 - 0.48 9.2 29.3 0.29 9.9 16.1 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF572 PF04502.13 CDJ50001.1 - 0.65 9.6 39.2 1.3 8.6 39.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pox_Ag35 PF03286.14 CDJ50001.1 - 0.9 9.3 23.8 0.032 14.0 10.1 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF908 PF06012.12 CDJ50001.1 - 1.1 8.7 24.3 1.4 8.3 3.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) BORG_CEP PF14957.6 CDJ50001.1 - 1.1 10.5 25.8 0.66 11.2 12.2 2.3 2 0 0 2 2 2 0 Cdc42 effector TRAP_alpha PF03896.16 CDJ50001.1 - 1.2 8.3 19.7 0.81 8.8 0.8 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 CDJ50001.1 - 1.3 7.3 32.7 0.063 11.6 17.8 2.1 2 0 0 2 2 2 0 CDC45-like protein PNISR PF15996.5 CDJ50001.1 - 1.3 9.3 47.2 0.74 10.1 24.7 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR FAM60A PF15396.6 CDJ50001.1 - 1.3 8.9 28.5 0.88 9.5 16.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF3295 PF11702.8 CDJ50001.1 - 1.9 7.7 32.0 0.2 10.9 16.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) V_ATPase_I PF01496.19 CDJ50001.1 - 2.7 5.8 35.3 0.29 9.0 17.6 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GCD14 PF08704.10 CDJ50001.1 - 3.2 7.3 18.9 1.2 8.7 2.3 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit CPSF100_C PF13299.6 CDJ50001.1 - 3.2 7.9 34.9 2 8.6 20.4 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 CDJ50001.1 - 3.7 7.3 43.8 1.1 9.1 25.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TCP PF03634.13 CDJ50001.1 - 5.3 7.6 33.5 1.7 9.2 17.5 2.6 2 0 0 2 2 2 0 TCP family transcription factor DUF2052 PF09747.9 CDJ50001.1 - 6.6 6.8 48.6 6.5 6.8 29.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Methyltransf_25 PF13649.6 CDJ50001.1 - 6.8 7.5 6.5 1.1 10.0 0.2 2.6 2 1 1 3 3 2 0 Methyltransferase domain Ocular_alb PF02101.15 CDJ50002.1 - 0.16 10.8 4.5 0.25 10.2 4.5 1.4 1 0 0 1 1 1 0 Ocular albinism type 1 protein SR-25 PF10500.9 CDJ50002.1 - 3 7.4 56.3 0.063 12.9 23.6 3.5 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein BAT2_N PF07001.11 CDJ50002.1 - 3.7 8.0 29.9 5.7 7.4 20.5 2.3 2 0 0 2 2 2 0 BAT2 N-terminus COX14 PF14880.6 CDJ50002.1 - 3.7 7.5 4.5 1.6 8.6 0.3 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DAP_B PF07930.12 CDJ50002.1 - 4.4 7.2 6.9 28 4.6 5.2 2.2 1 1 1 2 2 2 0 D-aminopeptidase, domain B U1snRNP70_N PF12220.8 CDJ50002.1 - 5.1 7.8 8.8 0.43 11.3 2.2 2.5 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Utp14 PF04615.13 CDJ50002.1 - 8.1 4.9 20.8 11 4.4 20.8 1.1 1 0 0 1 1 1 0 Utp14 protein DUF3807 PF12720.7 CDJ50002.1 - 8.6 6.6 19.6 9.5 6.4 13.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Nop14 PF04147.12 CDJ50003.1 - 0.82 7.8 47.0 0.37 8.9 35.5 2.0 2 0 0 2 2 2 0 Nop14-like family DNA_ligase_A_M PF01068.21 CDJ50004.1 - 7.9e-06 25.7 10.5 4.5e-05 23.2 0.0 2.6 2 1 0 2 2 2 1 ATP dependent DNA ligase domain Serglycin PF04360.12 CDJ50004.1 - 0.00031 20.7 1.1 0.00031 20.7 1.1 2.1 2 0 0 2 2 1 1 Serglycin SR-25 PF10500.9 CDJ50004.1 - 0.0015 18.2 2.9 0.0015 18.2 2.9 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SID-1_RNA_chan PF13965.6 CDJ50004.1 - 0.011 14.2 0.7 0.01 14.3 0.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4484 PF14831.6 CDJ50004.1 - 0.012 15.7 5.1 0.012 15.7 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) eIF-3_zeta PF05091.12 CDJ50004.1 - 0.038 13.0 23.7 0.064 12.2 23.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Serinc PF03348.15 CDJ50004.1 - 0.12 11.2 8.6 0.18 10.7 8.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CDC45 PF02724.14 CDJ50004.1 - 0.2 9.9 18.4 0.28 9.4 18.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 CDJ50004.1 - 0.29 9.2 19.0 0.4 8.7 19.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PBP1_TM PF14812.6 CDJ50004.1 - 0.31 11.4 10.7 0.68 10.3 10.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_11 PF13086.6 CDJ50004.1 - 0.53 10.0 20.3 1.4 8.7 20.3 1.6 1 0 0 1 1 1 0 AAA domain Zip PF02535.22 CDJ50004.1 - 1.1 8.4 9.5 2.7 7.1 9.5 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 CDJ50004.1 - 1.2 8.5 22.9 2.1 7.7 22.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ALMT PF11744.8 CDJ50004.1 - 1.3 7.8 13.7 2.1 7.1 13.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2370 PF10176.9 CDJ50004.1 - 1.4 8.5 9.2 3.5 7.2 9.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) HCO3_cotransp PF00955.21 CDJ50004.1 - 1.5 7.5 5.6 2.1 7.1 5.6 1.1 1 0 0 1 1 1 0 HCO3- transporter family Connexin PF00029.19 CDJ50004.1 - 2.2 8.0 18.5 3.7 7.2 18.5 1.3 1 0 0 1 1 1 0 Connexin Ureide_permease PF07168.11 CDJ50004.1 - 2.5 6.7 7.3 5.4 5.7 7.3 1.5 1 0 0 1 1 1 0 Ureide permease DAG_kinase_N PF14513.6 CDJ50004.1 - 2.6 8.2 21.2 0.45 10.7 15.8 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus CSG2 PF16965.5 CDJ50004.1 - 6.2 5.7 10.5 9.3 5.1 10.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Afi1 PF07792.12 CDJ50004.1 - 7.3 7.1 20.1 14 6.2 20.1 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FAM60A PF15396.6 CDJ50004.1 - 8.7 6.3 20.0 1.8 8.5 14.9 2.0 2 0 0 2 2 2 0 Protein Family FAM60A NARP1 PF12569.8 CDJ50004.1 - 9.3 5.0 21.3 45 2.8 22.1 1.6 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 CrgA PF06781.12 CDJ50004.1 - 9.8 6.3 14.8 0.082 13.0 0.7 3.0 1 1 1 2 2 1 0 Cell division protein CrgA DNA_ligase_A_C PF04679.15 CDJ50005.1 - 7e-17 61.9 0.0 1.1e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_M PF01068.21 CDJ50005.1 - 0.0002 21.1 0.0 0.00038 20.2 0.0 1.4 2 0 0 2 2 2 1 ATP dependent DNA ligase domain Presenilin PF01080.17 CDJ50007.1 - 0.0004 19.3 23.2 0.0004 19.3 23.2 2.1 2 0 0 2 2 2 1 Presenilin eIF3_subunit PF08597.10 CDJ50007.1 - 0.0078 16.2 11.0 0.0078 16.2 11.0 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit Peptidase_S64 PF08192.11 CDJ50007.1 - 1.9 6.8 25.1 3.4 6.1 25.1 1.4 1 0 0 1 1 1 0 Peptidase family S64 ABC_membrane PF00664.23 CDJ50008.1 - 4.6e-18 65.9 0.6 9.4e-18 64.8 0.6 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ50008.1 - 7.3e-08 33.0 0.1 2.5e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Mg_chelatase PF01078.21 CDJ50008.1 - 0.0021 17.5 0.1 9.7 5.5 0.0 3.8 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI FTZ PF03867.14 CDJ50008.1 - 0.0064 16.1 6.1 0.0098 15.5 6.1 1.2 1 0 0 1 1 1 1 Fushi tarazu (FTZ), N-terminal region AAA_29 PF13555.6 CDJ50008.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Spt20 PF12090.8 CDJ50008.1 - 0.14 11.8 10.3 0.23 11.0 10.3 1.3 1 0 0 1 1 1 0 Spt20 family AAA_16 PF13191.6 CDJ50008.1 - 0.2 12.0 0.0 0.2 12.0 0.0 3.0 2 1 1 3 3 3 0 AAA ATPase domain Shadoo PF14999.6 CDJ50008.1 - 0.45 10.6 17.9 0.05 13.7 7.3 2.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF2722 PF10846.8 CDJ50008.1 - 1.2 8.0 6.7 1.8 7.4 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ50008.1 - 2.8 7.9 11.0 4.3 7.2 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trp_oprn_chp PF09534.10 CDJ50008.1 - 4.7 7.0 36.2 2.8 7.7 16.0 2.7 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Collagen PF01391.18 CDJ50009.1 - 2.9e-06 26.9 137.7 0.0014 18.3 34.6 6.9 4 1 3 7 7 7 4 Collagen triple helix repeat (20 copies) DUF2126 PF09899.9 CDJ50016.1 - 0.68 7.9 9.4 0.97 7.4 9.4 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) NPR3 PF03666.13 CDJ50016.1 - 0.82 8.4 25.8 0.98 8.1 17.6 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 CRT10 PF08728.10 CDJ50016.1 - 1.3 7.1 7.7 1.4 7.0 7.7 1.1 1 0 0 1 1 1 0 CRT10 Draxin PF15550.6 CDJ50016.1 - 6.5 6.5 19.7 2.3 8.0 17.1 1.5 1 1 0 1 1 1 0 Draxin PGA_cap PF09587.10 CDJ50016.1 - 10 5.5 9.5 21 4.4 9.5 1.5 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DUF3413 PF11893.8 CDJ50017.1 - 1.1 8.3 4.1 1.8 7.7 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) DUF3729 PF12526.8 CDJ50017.1 - 8.6 8.0 12.9 2.5 9.7 9.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) zf-C2H2 PF00096.26 CDJ50018.1 - 2.7e-05 24.4 0.3 5.9e-05 23.3 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CDJ50018.1 - 0.0072 17.0 0.9 0.019 15.6 0.0 2.0 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats XPA_N PF01286.18 CDJ50018.1 - 0.018 15.1 0.1 0.04 13.9 0.1 1.5 1 0 0 1 1 1 0 XPA protein N-terminal zf-C2H2_4 PF13894.6 CDJ50018.1 - 0.059 14.2 0.3 0.17 12.8 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger MORN PF02493.20 CDJ50019.1 - 1.2e-16 59.5 17.9 2.6e-05 23.8 0.7 6.4 6 0 0 6 6 6 5 MORN repeat Dickkopf_N PF04706.12 CDJ50022.1 - 0.24 11.9 10.7 35 5.0 0.0 4.2 2 1 2 4 4 4 0 Dickkopf N-terminal cysteine-rich region Lustrin_cystein PF14625.6 CDJ50022.1 - 1.5 9.3 26.0 1.8 9.0 0.5 4.7 2 1 2 4 4 4 0 Lustrin, cysteine-rich repeated domain Ephrin_rec_like PF07699.13 CDJ50023.1 - 0.0073 16.1 87.2 0.02 14.7 3.1 10.6 5 3 6 11 11 11 6 Putative ephrin-receptor like NCD3G PF07562.14 CDJ50023.1 - 0.04 13.9 0.4 0.04 13.9 0.4 9.1 6 2 4 10 10 10 0 Nine Cysteines Domain of family 3 GPCR Lustrin_cystein PF14625.6 CDJ50023.1 - 8.3 6.9 87.5 2.1 8.8 0.5 12.5 6 3 5 11 11 11 0 Lustrin, cysteine-rich repeated domain Ephrin_rec_like PF07699.13 CDJ50024.1 - 0.035 13.9 2.6 0.035 13.9 2.6 2.6 2 0 0 2 2 2 0 Putative ephrin-receptor like TNFR_c6 PF00020.18 CDJ50024.1 - 2.6 8.5 10.3 0.096 13.1 3.6 2.2 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region CarboxypepD_reg PF13620.6 CDJ50025.1 - 0.048 13.9 0.4 0.22 11.8 0.1 2.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Pkinase PF00069.25 CDJ50026.1 - 4.5e-09 36.1 0.0 4.5e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ50026.1 - 0.1 11.9 0.0 4.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase MORN PF02493.20 CDJ50028.1 - 1.8e-12 46.4 7.9 8.7e-08 31.6 2.5 3.5 3 0 0 3 3 3 3 MORN repeat LRR_9 PF14580.6 CDJ50029.1 - 5.9e-16 58.5 0.0 7e-06 25.7 0.0 3.2 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 CDJ50029.1 - 9.6e-15 54.5 8.9 2.4e-06 27.8 1.0 5.2 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ50029.1 - 1.2e-09 37.7 4.4 0.0055 16.4 0.4 5.4 4 1 2 6 6 6 4 Leucine rich repeat LRR_6 PF13516.6 CDJ50029.1 - 0.05 13.7 4.0 12 6.3 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Toxin_22 PF08092.11 CDJ50029.1 - 1 9.4 4.7 67 3.7 0.6 3.5 3 0 0 3 3 3 0 Magi peptide toxin family TolA_bind_tri PF16331.5 CDJ50030.1 - 0.0014 18.6 1.1 0.0014 18.6 1.1 9.7 6 1 3 10 10 10 2 TolA binding protein trimerisation EF-hand_1 PF00036.32 CDJ50031.1 - 1.1e-16 59.0 0.8 1.8e-07 30.2 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CDJ50031.1 - 2.3e-16 58.3 2.9 2e-07 30.4 0.2 3.6 3 1 1 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 CDJ50031.1 - 7e-15 55.2 0.7 1.9e-08 34.6 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CDJ50031.1 - 1.2e-11 44.7 0.0 2.2e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ50031.1 - 2.5e-09 36.2 0.5 4.5e-05 22.7 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ50031.1 - 2.7e-05 23.9 2.8 0.0009 19.0 0.2 3.1 1 1 3 4 4 4 1 EF-hand domain pair LNS2 PF08235.13 CDJ50032.1 - 8.8e-94 313.2 0.0 1.2e-93 312.7 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CDJ50032.1 - 2.7e-29 101.1 0.0 4.6e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 CDJ50032.1 - 8.3e-20 70.8 0.0 1.7e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Apt1 PF10351.9 CDJ50032.1 - 0.25 10.2 11.1 0.61 8.9 11.1 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ50032.1 - 3.8 5.9 11.6 6.7 5.1 11.6 1.3 1 0 0 1 1 1 0 Macoilin family Kinesin PF00225.23 CDJ50033.1 - 2.2e-80 270.1 3.4 1.9e-73 247.3 0.1 2.7 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ50033.1 - 0.00039 20.4 0.0 0.13 12.2 0.0 2.8 1 1 1 2 2 2 2 Microtubule binding DUF3971 PF13116.6 CDJ50033.1 - 0.055 13.0 0.3 0.09 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function BRICHOS PF04089.14 CDJ50033.1 - 1.5 9.1 3.9 7.2 6.9 3.6 2.4 1 1 0 1 1 1 0 BRICHOS domain Cgr1 PF03879.14 CDJ50034.1 - 6.4e-06 26.5 24.0 1.2e-05 25.6 24.0 1.4 1 0 0 1 1 1 1 Cgr1 family AAA_11 PF13086.6 CDJ50034.1 - 0.043 13.6 10.4 0.016 15.0 8.2 1.4 2 0 0 2 2 2 0 AAA domain DUF4200 PF13863.6 CDJ50035.1 - 2.7e-12 47.1 16.1 2.7e-12 47.1 16.1 4.0 3 1 0 3 3 3 2 Domain of unknown function (DUF4200) Adeno_E4 PF05385.11 CDJ50035.1 - 0.22 11.7 1.0 0.95 9.6 0.2 2.2 2 0 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein TrbI_Ftype PF09677.10 CDJ50035.1 - 0.68 10.3 10.8 2.9 8.3 0.9 2.7 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) DUF948 PF06103.11 CDJ50035.1 - 9.2 6.6 8.7 12 6.3 2.1 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ADK PF00406.22 CDJ50036.1 - 7.4e-31 107.3 0.0 2.4e-14 53.7 0.0 2.8 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CDJ50036.1 - 7.5e-21 75.0 5.9 1.3e-09 38.6 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 CDJ50036.1 - 3.8e-11 43.6 1.3 7.9e-07 29.7 0.0 3.5 3 1 1 4 4 4 2 AAA domain AAA_33 PF13671.6 CDJ50036.1 - 8.7e-06 26.0 18.1 6.4e-05 23.2 0.1 3.9 4 1 0 4 4 4 2 AAA domain dNK PF01712.19 CDJ50036.1 - 0.023 14.6 0.1 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase Hydin_ADK PF17213.3 CDJ50036.1 - 0.039 14.2 14.3 0.46 10.7 0.0 4.9 5 1 1 6 6 6 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 CDJ50036.1 - 0.13 11.0 3.4 0.24 10.1 3.4 1.4 1 0 0 1 1 1 0 Presenilin Cytidylate_kin2 PF13189.6 CDJ50036.1 - 0.18 11.9 2.5 1.6 8.8 0.0 3.3 3 1 1 4 4 4 0 Cytidylate kinase-like family Rot1 PF10681.9 CDJ50036.1 - 0.44 10.0 1.7 0.83 9.1 1.7 1.4 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Peroxin-13_N PF04088.13 CDJ50036.1 - 3.9 7.8 6.0 2.9 8.1 0.4 2.8 3 0 0 3 3 3 0 Peroxin 13, N-terminal region EF_TS PF00889.19 CDJ50037.1 - 5.2e-32 111.2 1.4 8e-31 107.3 1.4 2.3 1 1 0 1 1 1 1 Elongation factor TS SR-25 PF10500.9 CDJ50037.1 - 0.0058 16.3 9.3 0.0058 16.3 9.3 2.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 CDJ50037.1 - 6.1 5.3 10.3 0.63 8.5 3.3 2.6 2 0 0 2 2 2 0 Macoilin family MAP65_ASE1 PF03999.12 CDJ50038.1 - 0.0013 17.5 0.1 0.0013 17.5 0.1 7.6 6 2 1 7 7 7 3 Microtubule associated protein (MAP65/ASE1 family) Sin_N PF04801.13 CDJ50038.1 - 2.1 7.5 0.0 2.1 7.5 0.0 7.8 6 1 1 7 7 7 0 Sin-like protein conserved region SR-25 PF10500.9 CDJ50039.1 - 0.0008 19.1 2.6 0.0008 19.1 2.6 6.7 4 2 3 7 7 7 2 Nuclear RNA-splicing-associated protein LTV PF04180.14 CDJ50039.1 - 0.0024 17.7 16.9 0.0024 17.7 16.9 4.0 3 1 1 5 5 5 1 Low temperature viability protein HPPK PF01288.20 CDJ50039.1 - 2.8 8.5 0.0 2.8 8.5 0.0 3.4 3 1 1 4 4 4 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) RskA PF10099.9 CDJ50039.1 - 6.7 7.0 127.3 0.12 12.7 20.2 7.5 2 1 4 6 6 6 0 Anti-sigma-K factor rskA Vfa1 PF08432.10 CDJ50039.1 - 8.7 6.6 49.7 7.6 6.8 26.4 4.6 4 1 0 4 4 4 0 AAA-ATPase Vps4-associated protein 1 DUF4834 PF16118.5 CDJ50040.1 - 2.1e-05 25.4 8.5 0.088 13.8 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ50040.1 - 0.0029 17.3 1.0 0.98 9.1 0.0 2.2 2 0 0 2 2 2 2 FAM176 family TFIIA PF03153.13 CDJ50040.1 - 0.0064 16.5 38.8 0.0081 16.2 38.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit G0-G1_switch_2 PF15103.6 CDJ50040.1 - 0.14 12.6 12.2 0.55 10.7 0.2 2.5 2 0 0 2 2 2 0 G0/G1 switch protein 2 Connexin PF00029.19 CDJ50040.1 - 0.22 11.3 1.6 2.8 7.6 0.4 2.1 2 0 0 2 2 2 0 Connexin Spore_coat_CotO PF14153.6 CDJ50040.1 - 0.26 11.2 15.8 0.68 9.8 7.6 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Spt20 PF12090.8 CDJ50040.1 - 0.71 9.4 37.9 1 9.0 26.0 2.1 2 0 0 2 2 2 0 Spt20 family BORG_CEP PF14957.6 CDJ50040.1 - 0.79 10.9 5.9 3.5 8.8 1.4 2.2 2 0 0 2 2 2 0 Cdc42 effector Baculo_PP31 PF05311.11 CDJ50040.1 - 0.97 8.9 7.7 1.7 8.0 1.6 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) eIF-3_zeta PF05091.12 CDJ50040.1 - 3.5 6.5 13.3 0.13 11.2 4.9 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2722 PF10846.8 CDJ50040.1 - 6.1 5.7 35.4 0.65 8.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) CDC45 PF02724.14 CDJ50041.1 - 0.92 7.7 23.9 1.4 7.1 23.9 1.2 1 0 0 1 1 1 0 CDC45-like protein LMBR1 PF04791.16 CDJ50041.1 - 0.95 8.3 14.5 1.4 7.8 14.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SID-1_RNA_chan PF13965.6 CDJ50041.1 - 1.1 7.6 10.8 1.7 7.0 10.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ALMT PF11744.8 CDJ50041.1 - 3.4 6.4 25.0 7 5.4 25.0 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter CRT10 PF08728.10 CDJ50041.1 - 4 5.5 15.4 5.4 5.1 15.4 1.1 1 0 0 1 1 1 0 CRT10 V_ATPase_I PF01496.19 CDJ50041.1 - 5.4 4.8 28.3 9 4.1 28.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2722 PF10846.8 CDJ50042.1 - 0.014 14.4 0.7 0.014 14.4 0.7 5.7 5 1 1 6 6 6 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ50042.1 - 0.023 14.7 0.0 0.023 14.7 0.0 7.5 6 3 1 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 ZapB PF06005.12 CDJ50042.1 - 0.63 10.5 0.0 0.63 10.5 0.0 8.6 6 2 0 6 6 6 0 Cell division protein ZapB Spt20 PF12090.8 CDJ50044.1 - 1.7e-07 31.1 55.8 5.2e-05 23.0 20.4 3.4 3 0 0 3 3 3 3 Spt20 family DUF2722 PF10846.8 CDJ50044.1 - 0.00017 20.7 2.5 0.00017 20.7 2.5 3.7 4 0 0 4 4 4 3 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ50044.1 - 0.14 12.1 70.7 0.0092 16.0 24.6 3.6 3 1 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit PIP5K PF01504.18 CDJ50044.1 - 0.6 9.3 10.5 0.17 11.1 5.8 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase SLC12 PF03522.15 CDJ50044.1 - 4.1 6.3 15.9 0.94 8.4 11.8 1.8 2 0 0 2 2 2 0 Solute carrier family 12 Presenilin PF01080.17 CDJ50045.1 - 0.23 10.2 37.9 0.28 9.9 37.9 1.0 1 0 0 1 1 1 0 Presenilin EBP50_C PF09007.11 CDJ50045.1 - 1.7 9.6 20.9 2.2 9.3 20.9 1.2 1 0 0 1 1 1 0 EBP50, C-terminal RR_TM4-6 PF06459.12 CDJ50045.1 - 2 8.2 34.2 2.3 8.0 34.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Kei1 PF08552.11 CDJ50045.1 - 4.5 7.1 19.8 5.5 6.8 19.8 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Endostatin PF06482.11 CDJ50045.1 - 5.1 6.5 29.2 5.7 6.3 29.2 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin ALMT PF11744.8 CDJ50045.1 - 6.2 5.5 24.5 7.2 5.3 24.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter ANAPC1 PF12859.7 CDJ50046.1 - 8.5 7.0 10.5 58 4.3 10.5 2.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 IBP39 PF11422.8 CDJ50047.1 - 0.042 13.6 0.0 2.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Initiator binding protein 39 kDa DUF384 PF04064.13 CDJ50047.1 - 0.16 11.8 2.1 13 5.7 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF384) HlyD_D4 PF16572.5 CDJ50049.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.9 3 1 0 3 3 3 0 Long alpha hairpin domain of cation efflux system protein, CusB ETRAMP PF09716.10 CDJ50049.1 - 7.1 6.8 7.3 0.63 10.1 0.2 2.4 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Jun PF03957.13 CDJ50049.1 - 7.3 6.4 14.4 0.57 10.0 9.1 1.7 2 0 0 2 2 2 0 Jun-like transcription factor Actin PF00022.19 CDJ50050.1 - 4.6e-49 167.1 0.0 5.5e-47 160.3 0.0 2.0 1 1 0 1 1 1 1 Actin Zip PF02535.22 CDJ50052.1 - 4.4e-19 68.9 12.6 4.4e-19 68.9 12.6 2.5 1 1 0 2 2 1 1 ZIP Zinc transporter DDHD PF02862.17 CDJ50052.1 - 0.027 14.6 2.0 0.07 13.3 1.1 2.0 2 0 0 2 2 2 0 DDHD domain Spt20 PF12090.8 CDJ50052.1 - 0.076 12.6 32.1 0.16 11.6 32.1 1.5 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ50052.1 - 0.097 11.6 22.3 0.16 10.9 22.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ50052.1 - 0.16 13.0 9.3 10 7.1 11.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ50052.1 - 0.22 11.5 11.3 0.52 10.2 10.8 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ50052.1 - 0.55 10.2 4.3 0.63 10.0 3.2 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Endonuc_Holl PF10107.9 CDJ50052.1 - 0.56 10.0 7.9 1.1 9.1 7.9 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase BRF1 PF07741.13 CDJ50052.1 - 0.74 10.2 12.3 0.59 10.5 8.5 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain MAT1 PF06391.13 CDJ50052.1 - 0.77 9.6 21.1 0.091 12.6 16.3 1.7 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Nbs1_C PF08599.10 CDJ50052.1 - 1.1 9.4 6.0 2.6 8.2 6.0 1.5 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 AIF_C PF14721.6 CDJ50052.1 - 1.3 9.4 6.4 51 4.2 6.8 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pex14_N PF04695.13 CDJ50052.1 - 1.7 9.3 24.2 1.2 9.8 20.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 CDJ50052.1 - 1.8 8.6 14.2 3 7.8 14.2 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Connexin PF00029.19 CDJ50052.1 - 2.7 7.7 6.0 4.3 7.0 4.9 1.8 2 0 0 2 2 2 0 Connexin Ctr PF04145.15 CDJ50052.1 - 2.9 8.5 10.4 22 5.7 0.2 2.6 2 1 0 2 2 2 0 Ctr copper transporter family EIIBC-GUT_N PF03612.14 CDJ50052.1 - 4.5 7.0 10.6 5.9 6.6 8.7 1.9 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus V_ATPase_I PF01496.19 CDJ50052.1 - 6.9 4.4 8.9 13 3.6 8.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Band_3_cyto PF07565.13 CDJ50052.1 - 8.5 6.1 11.0 14 5.3 11.0 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ALMT PF11744.8 CDJ50052.1 - 8.7 5.0 8.0 18 4.0 8.0 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3464 PF11947.8 CDJ50052.1 - 9.1 6.0 12.0 0.051 13.3 1.9 2.3 2 1 0 2 2 2 0 Photosynthesis affected mutant 68 MPM1 PF17234.2 CDJ50052.1 - 9.4 6.5 12.8 2.1 8.5 9.5 1.5 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 RskA PF10099.9 CDJ50054.1 - 5.7e-06 26.8 17.0 7.4e-06 26.4 17.0 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Dehydrin PF00257.19 CDJ50054.1 - 0.00011 22.8 6.6 0.00012 22.7 6.6 1.1 1 0 0 1 1 1 1 Dehydrin TFIIA PF03153.13 CDJ50054.1 - 0.00013 22.1 28.4 0.00014 22.1 28.4 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit IF-2B PF01008.17 CDJ50054.1 - 0.0079 15.4 0.1 0.0079 15.4 0.1 1.8 2 0 0 2 2 2 1 Initiation factor 2 subunit family Sporozoite_P67 PF05642.11 CDJ50054.1 - 0.0095 14.1 3.5 0.011 13.9 3.5 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen SR-25 PF10500.9 CDJ50054.1 - 0.014 15.0 19.6 0.018 14.6 19.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EIF4E-T PF10477.9 CDJ50054.1 - 0.016 14.1 16.9 0.017 14.0 16.9 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DDHD PF02862.17 CDJ50054.1 - 0.018 15.2 7.1 0.02 15.1 7.1 1.1 1 0 0 1 1 1 0 DDHD domain Suf PF05843.14 CDJ50054.1 - 0.026 14.5 12.3 0.027 14.5 12.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF5427 PF10310.9 CDJ50054.1 - 0.05 12.6 14.7 0.057 12.4 14.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Spt20 PF12090.8 CDJ50054.1 - 0.055 13.1 36.8 0.07 12.7 36.8 1.1 1 0 0 1 1 1 0 Spt20 family Connexin PF00029.19 CDJ50054.1 - 0.056 13.2 8.2 0.074 12.8 8.2 1.1 1 0 0 1 1 1 0 Connexin DUF572 PF04502.13 CDJ50054.1 - 0.057 13.0 9.6 0.061 12.9 9.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Tim54 PF11711.8 CDJ50054.1 - 0.059 12.2 7.0 0.067 12.0 7.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SID-1_RNA_chan PF13965.6 CDJ50054.1 - 0.068 11.6 0.8 0.061 11.7 0.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4407 PF14362.6 CDJ50054.1 - 0.076 12.4 8.7 0.089 12.1 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0524 PF15823.5 CDJ50054.1 - 0.082 12.3 7.9 0.099 12.0 7.9 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 BORG_CEP PF14957.6 CDJ50054.1 - 0.1 13.7 10.7 0.13 13.4 10.7 1.2 1 0 0 1 1 1 0 Cdc42 effector Ribosomal_60s PF00428.19 CDJ50054.1 - 0.11 13.0 8.8 0.27 11.8 8.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Macoilin PF09726.9 CDJ50054.1 - 0.14 10.7 11.9 0.18 10.3 11.9 1.1 1 0 0 1 1 1 0 Macoilin family Spore_coat_CotO PF14153.6 CDJ50054.1 - 0.15 12.0 14.2 0.16 11.9 14.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF3408 PF11888.8 CDJ50054.1 - 0.17 12.0 8.8 0.23 11.6 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) CPSF100_C PF13299.6 CDJ50054.1 - 0.18 12.0 7.6 0.24 11.5 7.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 CDJ50054.1 - 0.2 11.5 11.2 0.23 11.3 11.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4820 PF16091.5 CDJ50054.1 - 0.2 11.0 9.2 0.24 10.7 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF719 PF05334.13 CDJ50054.1 - 0.21 11.8 10.5 0.27 11.4 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) SpoIIP PF07454.11 CDJ50054.1 - 0.24 10.8 11.0 0.28 10.6 11.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Hid1 PF12722.7 CDJ50054.1 - 0.24 9.5 10.4 0.23 9.5 10.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TERB2 PF15101.6 CDJ50054.1 - 0.31 11.1 22.8 0.33 11.0 21.2 1.7 2 0 0 2 2 2 0 Telomere-associated protein TERB2 GREB1 PF15782.5 CDJ50054.1 - 0.35 7.9 20.5 0.41 7.7 20.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 CDJ50054.1 - 0.37 10.8 8.9 0.4 10.7 8.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CDJ50054.1 - 0.41 9.8 5.9 0.43 9.7 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.13 CDJ50054.1 - 0.5 9.4 13.4 0.62 9.1 13.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3675 PF12428.8 CDJ50054.1 - 0.57 10.8 3.8 0.91 10.1 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF913 PF06025.12 CDJ50054.1 - 0.57 9.1 7.8 0.65 8.9 7.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4770 PF15994.5 CDJ50054.1 - 0.68 10.1 12.3 0.95 9.7 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) eIF3_subunit PF08597.10 CDJ50054.1 - 0.84 9.5 13.1 1.1 9.1 13.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SPX PF03105.19 CDJ50054.1 - 1.1 9.1 17.4 1.2 9.0 17.4 1.0 1 0 0 1 1 1 0 SPX domain eIF-3_zeta PF05091.12 CDJ50054.1 - 1.1 8.1 15.4 1.3 7.9 15.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MAJIN PF15077.6 CDJ50054.1 - 1.2 8.9 8.2 1.4 8.6 8.2 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein PAT1 PF09770.9 CDJ50054.1 - 1.2 7.3 25.4 1.5 7.0 25.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.6 CDJ50054.1 - 1.4 8.9 10.6 2 8.4 10.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A EPL1 PF10513.9 CDJ50054.1 - 1.5 9.1 14.4 2 8.8 14.4 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like EIIBC-GUT_N PF03612.14 CDJ50054.1 - 1.6 8.4 9.0 2 8.1 9.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CobT PF06213.12 CDJ50054.1 - 1.8 7.9 20.4 2.4 7.5 20.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SLC12 PF03522.15 CDJ50054.1 - 1.9 7.4 11.8 2.1 7.3 11.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Paf1 PF03985.13 CDJ50054.1 - 2 7.3 16.6 2.4 7.1 16.6 1.1 1 0 0 1 1 1 0 Paf1 MMU163 PF17119.5 CDJ50054.1 - 2.3 7.3 9.3 3.1 6.9 9.3 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis FAM176 PF14851.6 CDJ50054.1 - 2.3 7.9 7.7 3.2 7.4 7.7 1.2 1 0 0 1 1 1 0 FAM176 family Hydin_ADK PF17213.3 CDJ50054.1 - 2.5 8.3 16.1 3.7 7.8 16.1 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF4834 PF16118.5 CDJ50054.1 - 2.6 9.1 15.8 4.3 8.4 15.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RED_N PF07808.13 CDJ50054.1 - 2.6 7.5 12.9 3.6 7.1 12.9 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region CSG2 PF16965.5 CDJ50054.1 - 2.7 6.8 5.6 3.1 6.7 5.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Folate_carrier PF01770.18 CDJ50054.1 - 2.9 6.6 6.8 3.4 6.3 6.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier EOS1 PF12326.8 CDJ50054.1 - 2.9 7.8 6.9 2.8 7.8 6.3 1.3 2 0 0 2 2 1 0 N-glycosylation protein Apt1 PF10351.9 CDJ50054.1 - 3.3 6.5 15.0 3.9 6.2 15.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Band_3_cyto PF07565.13 CDJ50054.1 - 3.4 7.4 14.0 4.2 7.1 14.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AIF_C PF14721.6 CDJ50054.1 - 3.5 8.0 9.4 5.2 7.4 9.4 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CLN3 PF02487.17 CDJ50054.1 - 3.7 6.5 10.2 4.5 6.2 10.2 1.1 1 0 0 1 1 1 0 CLN3 protein Ureide_permease PF07168.11 CDJ50054.1 - 3.9 6.1 4.3 4.4 6.0 4.3 1.1 1 0 0 1 1 1 0 Ureide permease Ndc1_Nup PF09531.10 CDJ50054.1 - 4 6.0 16.0 4.3 5.9 16.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPF0560 PF10577.9 CDJ50054.1 - 4.3 5.7 21.2 5.1 5.5 21.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Lin-8 PF03353.15 CDJ50054.1 - 4.4 6.8 20.2 5.6 6.4 20.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MPM1 PF17234.2 CDJ50054.1 - 4.5 7.5 16.0 5.9 7.1 16.0 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF1387 PF07139.11 CDJ50054.1 - 4.6 6.9 17.4 5.8 6.6 17.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) API5 PF05918.11 CDJ50054.1 - 4.7 5.9 15.7 5.9 5.6 15.7 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SprA-related PF12118.8 CDJ50054.1 - 4.9 6.2 29.3 6.5 5.8 29.3 1.1 1 0 0 1 1 1 0 SprA-related family Membralin PF09746.9 CDJ50054.1 - 5.6 5.9 6.9 6.6 5.7 6.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein Mem_trans PF03547.18 CDJ50054.1 - 5.8 5.2 8.8 7.3 4.9 8.8 1.1 1 0 0 1 1 1 0 Membrane transport protein V_ATPase_I PF01496.19 CDJ50054.1 - 5.9 4.7 12.8 6.7 4.5 12.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NEMP PF10225.9 CDJ50054.1 - 6.1 6.4 6.9 7.2 6.2 6.9 1.1 1 0 0 1 1 1 0 NEMP family Gti1_Pac2 PF09729.9 CDJ50054.1 - 6.2 6.9 13.5 8 6.5 13.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family ALMT PF11744.8 CDJ50054.1 - 6.3 5.5 10.5 7.3 5.3 10.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Maf1 PF09174.10 CDJ50054.1 - 7.8 6.6 9.8 11 6.2 9.8 1.2 1 0 0 1 1 1 0 Maf1 regulator Spc7_N PF15402.6 CDJ50054.1 - 7.8 4.6 21.8 9.6 4.3 21.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF3292 PF11696.8 CDJ50054.1 - 8.1 4.7 15.1 9.7 4.4 15.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Nab6_mRNP_bdg PF10567.9 CDJ50054.1 - 8.7 5.7 10.8 11 5.4 10.8 1.1 1 0 0 1 1 1 0 RNA-recognition motif DUF2722 PF10846.8 CDJ50054.1 - 8.7 5.2 39.0 12 4.7 39.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CCDC106 PF15794.5 CDJ50054.1 - 8.9 5.9 17.3 13 5.5 17.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Spt20 PF12090.8 CDJ50055.1 - 0.0013 18.5 47.7 0.0014 18.3 11.5 3.2 3 0 0 3 3 3 3 Spt20 family DUF2722 PF10846.8 CDJ50055.1 - 0.029 13.3 0.0 0.029 13.3 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2722) DUF2207 PF09972.9 CDJ50055.1 - 0.12 11.1 0.0 0.28 9.9 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) WD40 PF00400.32 CDJ50055.1 - 0.18 12.8 0.5 35 5.5 0.1 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat EPL1 PF10513.9 CDJ50055.1 - 3 8.2 14.8 3.2 8.1 1.7 3.4 3 0 0 3 3 3 0 Enhancer of polycomb-like TFIIA PF03153.13 CDJ50055.1 - 5 7.0 68.6 0.3 11.1 4.5 3.3 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 CDJ50056.1 - 0.00053 20.7 0.2 0.11 13.4 0.1 3.6 4 0 0 4 4 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ50056.1 - 0.002 18.4 4.4 1.4 9.2 0.2 4.4 4 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Bd3614-deam PF14439.6 CDJ50056.1 - 0.018 15.1 0.6 0.047 13.8 0.6 1.7 1 0 0 1 1 1 0 Bd3614-like deaminase Na_H_antiport_3 PF07399.11 CDJ50056.1 - 0.058 12.3 3.6 0.063 12.2 0.2 2.4 2 1 1 3 3 3 0 Putative Na+/H+ antiporter DLIC PF05783.11 CDJ50056.1 - 0.13 11.0 0.0 0.13 11.0 0.0 2.7 2 1 1 3 3 3 0 Dynein light intermediate chain (DLIC) TFIIF_alpha PF05793.12 CDJ50056.1 - 0.2 10.2 14.0 0.017 13.8 7.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sporozoite_P67 PF05642.11 CDJ50056.1 - 0.28 9.2 13.4 0.38 8.8 10.4 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen TMEM223 PF14640.6 CDJ50056.1 - 0.44 10.7 3.2 7.2 6.7 0.1 3.1 3 0 0 3 3 3 0 Transmembrane protein 223 FAM176 PF14851.6 CDJ50056.1 - 1.3 8.7 0.0 1.3 8.7 0.0 4.5 5 1 0 5 5 5 0 FAM176 family E7 PF00527.18 CDJ50056.1 - 2.2 8.5 32.3 0.34 11.1 0.1 5.0 4 1 1 5 5 5 0 E7 protein, Early protein CDC45 PF02724.14 CDJ50056.1 - 2.3 6.4 31.8 0.014 13.7 19.8 2.4 2 2 0 2 2 2 0 CDC45-like protein Utp14 PF04615.13 CDJ50056.1 - 3.2 6.2 33.4 14 4.1 33.4 1.9 1 1 0 1 1 1 0 Utp14 protein GOLD_2 PF13897.6 CDJ50056.1 - 7.9 7.0 11.1 5 7.6 3.1 3.5 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking Utp14 PF04615.13 CDJ50057.1 - 0.00026 19.7 47.5 0.1 11.2 47.5 2.1 1 1 0 1 1 1 1 Utp14 protein SR-25 PF10500.9 CDJ50057.1 - 0.0041 16.8 12.5 0.0041 16.8 12.5 4.7 2 2 1 4 4 4 1 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CDJ50057.1 - 3.2 5.9 25.6 6.2 5.0 25.6 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AAA_lid_3 PF17862.1 CDJ50058.1 - 1e-11 44.4 0.1 4.6e-11 42.3 0.1 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDJ50058.1 - 4e-09 37.0 0.3 3e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Merozoite_SPAM PF07133.11 CDJ50058.1 - 0.0021 18.1 11.1 0.0029 17.6 11.1 1.2 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) DUF4667 PF15700.5 CDJ50058.1 - 0.003 17.7 10.5 0.0041 17.3 10.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) DUF3446 PF11928.8 CDJ50058.1 - 0.013 15.7 8.5 0.013 15.7 8.5 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Trypan_PARP PF05887.11 CDJ50058.1 - 0.034 14.1 11.6 0.056 13.4 11.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Lin-8 PF03353.15 CDJ50058.1 - 0.037 13.6 10.2 0.043 13.4 10.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF755 PF05501.11 CDJ50058.1 - 0.045 14.0 24.7 0.079 13.2 24.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) LAP1C PF05609.12 CDJ50058.1 - 0.063 12.4 13.3 0.075 12.1 13.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 CDJ50058.1 - 0.13 10.8 13.0 0.16 10.5 13.0 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ50058.1 - 0.13 11.1 13.7 0.15 10.9 13.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 CDJ50058.1 - 0.15 9.8 9.7 0.19 9.5 9.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM220 PF15487.6 CDJ50058.1 - 0.17 11.5 12.0 0.21 11.2 12.0 1.1 1 0 0 1 1 1 0 FAM220 family SpoIIIAH PF12685.7 CDJ50058.1 - 0.19 11.6 12.7 0.29 10.9 12.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Endomucin PF07010.12 CDJ50058.1 - 0.25 11.3 16.1 0.31 11.0 16.1 1.1 1 0 0 1 1 1 0 Endomucin DUF966 PF06136.13 CDJ50058.1 - 0.34 10.6 15.2 0.41 10.3 15.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4055 PF13264.6 CDJ50058.1 - 0.43 10.7 6.4 0.65 10.2 5.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4055) DUF2052 PF09747.9 CDJ50058.1 - 0.46 10.6 12.4 0.58 10.3 12.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ50058.1 - 0.49 10.2 14.3 0.61 9.9 14.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4551 PF15087.6 CDJ50058.1 - 0.67 8.7 12.0 0.75 8.6 12.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GREB1 PF15782.5 CDJ50058.1 - 0.92 6.6 14.2 1.1 6.3 14.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4637 PF15470.6 CDJ50058.1 - 0.94 9.2 15.8 1.6 8.5 15.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) V_ATPase_I PF01496.19 CDJ50058.1 - 1.3 6.8 3.0 1.4 6.8 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ50058.1 - 1.5 8.5 6.2 1.8 8.3 6.2 1.2 1 0 0 1 1 1 0 Connexin Plasmodium_Vir PF05795.11 CDJ50058.1 - 1.6 8.1 11.6 1.9 7.8 11.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1645 PF07816.11 CDJ50058.1 - 1.8 9.1 22.2 2.3 8.8 21.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) SAPS PF04499.15 CDJ50058.1 - 1.8 7.3 7.6 1.9 7.1 7.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 CDJ50058.1 - 2.2 8.3 5.6 2.9 7.9 5.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NESP55 PF06390.12 CDJ50058.1 - 3.5 7.1 23.5 5.2 6.6 23.5 1.3 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF4718 PF15842.5 CDJ50058.1 - 3.6 7.4 11.8 3.1 7.6 10.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4718) Menin PF05053.13 CDJ50058.1 - 3.7 5.8 13.7 4.4 5.5 13.7 1.0 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 CDJ50058.1 - 5.3 5.7 15.2 6.5 5.4 15.2 1.2 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 CDJ50058.1 - 6.1 6.3 7.6 8.5 5.8 7.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Cytomega_UL84 PF06284.11 CDJ50058.1 - 6.5 5.1 9.8 2.7 6.3 7.4 1.7 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein CDC45 PF02724.14 CDJ50058.1 - 6.6 4.9 15.2 8.3 4.6 15.2 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 CDJ50058.1 - 6.8 5.4 7.9 8.5 5.1 7.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Miga PF10265.9 CDJ50058.1 - 7 5.5 9.3 9.2 5.1 9.3 1.1 1 0 0 1 1 1 0 Mitoguardin SRP-alpha_N PF04086.13 CDJ50058.1 - 7.3 6.4 19.3 11 5.9 19.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MCM_bind PF09739.9 CDJ50058.1 - 8.5 4.7 10.5 10 4.5 10.5 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Peptidase_S64 PF08192.11 CDJ50058.1 - 9 4.6 13.8 11 4.4 13.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Med3 PF11593.8 CDJ50059.1 - 0.00041 19.7 13.8 0.00041 19.7 13.8 6.5 3 2 2 5 5 5 1 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ50059.1 - 0.0005 20.4 0.0 0.0005 20.4 0.0 6.0 1 1 2 4 4 4 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ50061.1 - 3.1e-05 24.9 11.2 7.3e-05 23.7 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ50061.1 - 0.0016 18.5 24.0 0.0022 18.1 24.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ50061.1 - 0.0017 17.2 5.9 0.0023 16.8 5.9 1.1 1 0 0 1 1 1 1 Presenilin RskA PF10099.9 CDJ50061.1 - 0.0018 18.6 3.1 0.0018 18.6 3.1 3.1 1 1 1 3 3 2 1 Anti-sigma-K factor rskA EphA2_TM PF14575.6 CDJ50061.1 - 0.0036 18.2 2.8 0.021 15.7 0.2 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain PigN PF04987.14 CDJ50061.1 - 0.0043 16.0 2.1 0.0043 16.0 2.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) SLD3 PF08639.10 CDJ50061.1 - 0.0047 15.8 4.8 0.0062 15.4 4.8 1.0 1 0 0 1 1 1 1 DNA replication regulator SLD3 BatD PF13584.6 CDJ50061.1 - 0.0086 14.9 6.6 0.011 14.6 6.6 1.1 1 0 0 1 1 1 1 Oxygen tolerance TMEM51 PF15345.6 CDJ50061.1 - 0.0091 15.9 0.7 0.0091 15.9 0.7 2.2 2 0 0 2 2 2 1 Transmembrane protein 51 Spore_coat_CotO PF14153.6 CDJ50061.1 - 0.01 15.8 11.4 0.074 13.0 0.1 2.1 2 0 0 2 2 2 0 Spore coat protein CotO COX16 PF14138.6 CDJ50061.1 - 0.013 16.0 2.4 0.055 14.0 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 AAA_11 PF13086.6 CDJ50061.1 - 0.016 15.0 5.7 0.02 14.7 5.7 1.1 1 0 0 1 1 1 0 AAA domain DUF4820 PF16091.5 CDJ50061.1 - 0.019 14.4 8.4 0.39 10.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) TMEM208_SND2 PF05620.11 CDJ50061.1 - 0.019 14.7 1.2 0.019 14.7 1.2 2.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Yip1 PF04893.17 CDJ50061.1 - 0.02 14.6 0.3 0.086 12.6 0.0 2.1 2 1 0 2 2 2 0 Yip1 domain Spt20 PF12090.8 CDJ50061.1 - 0.024 14.3 34.3 0.048 13.3 16.4 2.1 2 0 0 2 2 2 0 Spt20 family Vpu PF00558.19 CDJ50061.1 - 0.026 14.3 0.1 0.026 14.3 0.1 1.6 2 0 0 2 2 1 0 Vpu protein FAM176 PF14851.6 CDJ50061.1 - 0.027 14.1 4.0 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 FAM176 family Tmemb_9 PF05434.11 CDJ50061.1 - 0.028 14.3 0.1 0.028 14.3 0.1 2.1 2 0 0 2 2 2 0 TMEM9 MFS_Mycoplasma PF07672.13 CDJ50061.1 - 0.028 13.7 0.1 0.028 13.7 0.1 1.6 2 0 0 2 2 2 0 Mycoplasma MFS transporter TssO PF17561.2 CDJ50061.1 - 0.034 14.3 1.0 0.034 14.3 1.0 1.8 2 0 0 2 2 1 0 Type VI secretion system, TssO DUF3169 PF11368.8 CDJ50061.1 - 0.035 13.6 0.3 0.057 12.9 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) ArsP_2 PF11449.8 CDJ50061.1 - 0.036 13.3 0.4 0.04 13.1 0.4 1.1 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter Ribosomal_60s PF00428.19 CDJ50061.1 - 0.04 14.5 7.2 0.04 14.5 7.2 3.2 2 1 1 3 3 3 0 60s Acidic ribosomal protein EPL1 PF10513.9 CDJ50061.1 - 0.062 13.7 7.3 1.7 9.0 0.4 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Conotoxin PF02950.17 CDJ50061.1 - 0.079 14.0 2.0 0.079 14.0 2.0 2.6 2 1 0 2 2 2 0 Conotoxin SARAF PF06682.12 CDJ50061.1 - 0.095 12.3 7.1 0.26 10.9 7.1 1.6 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2722 PF10846.8 CDJ50061.1 - 0.12 11.3 26.5 0.044 12.7 11.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) CAF1 PF04857.20 CDJ50061.1 - 0.16 11.1 4.1 0.21 10.7 4.1 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Peptidase_S49_N PF08496.10 CDJ50061.1 - 0.18 11.9 5.5 0.51 10.4 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Claudin_2 PF13903.6 CDJ50061.1 - 0.21 11.3 2.1 0.22 11.2 0.4 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MDM10 PF12519.8 CDJ50061.1 - 0.26 10.1 3.1 0.33 9.8 3.1 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Eapp_C PF10238.9 CDJ50061.1 - 0.27 11.3 12.2 0.2 11.7 2.8 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4770 PF15994.5 CDJ50061.1 - 0.29 11.4 9.3 1.3 9.2 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF3371 PF11851.8 CDJ50061.1 - 0.32 12.1 13.5 0.24 12.5 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) DcuC PF03606.15 CDJ50061.1 - 0.36 9.2 0.0 0.36 9.2 0.0 1.4 2 0 0 2 2 1 0 C4-dicarboxylate anaerobic carrier Dpy19 PF10034.9 CDJ50061.1 - 0.63 8.2 5.2 0.15 10.3 2.0 1.4 1 1 1 2 2 2 0 Q-cell neuroblast polarisation HA2 PF04408.23 CDJ50061.1 - 0.88 9.9 6.9 1.6 9.0 0.2 2.2 2 0 0 2 2 2 0 Helicase associated domain (HA2) SKA1 PF07160.12 CDJ50061.1 - 1.1 9.0 9.7 0.39 10.5 2.3 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 7tm_1 PF00001.21 CDJ50061.1 - 1.2 8.4 3.1 0.67 9.2 0.7 1.5 1 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) UPF0239 PF06783.11 CDJ50061.1 - 1.3 9.3 12.3 0.14 12.3 1.5 2.2 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0239) YABBY PF04690.13 CDJ50061.1 - 1.6 9.3 8.2 1.5 9.4 0.9 2.2 2 0 0 2 2 2 0 YABBY protein WBP-1 PF11669.8 CDJ50061.1 - 2 9.1 16.7 0.075 13.7 7.2 2.3 1 1 1 2 2 2 0 WW domain-binding protein 1 BRF1 PF07741.13 CDJ50061.1 - 2.3 8.6 14.4 1.2 9.5 1.8 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain SID-1_RNA_chan PF13965.6 CDJ50061.1 - 2.5 6.4 6.0 0.34 9.3 0.8 1.7 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 DUF3782 PF12644.7 CDJ50061.1 - 2.5 8.3 8.0 0.2 11.8 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) MPP6 PF10175.9 CDJ50061.1 - 2.8 8.4 10.3 0.34 11.4 2.4 2.1 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Pex14_N PF04695.13 CDJ50061.1 - 3.3 8.4 19.3 1.6 9.3 7.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EIIBC-GUT_N PF03612.14 CDJ50061.1 - 3.4 7.4 8.8 2 8.1 0.4 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Scs3p PF10261.9 CDJ50061.1 - 3.9 6.9 7.6 0.79 9.2 0.1 2.0 1 1 1 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2681 PF10883.8 CDJ50061.1 - 4.6 7.7 24.9 0.55 10.7 11.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) FHIPEP PF00771.20 CDJ50061.1 - 5 5.5 14.1 0.041 12.4 1.3 2.0 1 1 1 2 2 2 0 FHIPEP family dsDNA_bind PF01984.20 CDJ50061.1 - 5.4 7.3 28.0 1.8 8.9 13.1 2.4 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Sin_N PF04801.13 CDJ50061.1 - 6.6 5.8 21.7 1.3 8.2 5.8 2.0 2 0 0 2 2 2 0 Sin-like protein conserved region CNDH2_N PF06278.11 CDJ50061.1 - 7.1 6.9 12.7 2 8.7 3.6 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CLN3 PF02487.17 CDJ50061.1 - 7.1 5.6 13.4 0.06 12.4 0.9 2.0 1 1 1 2 2 2 0 CLN3 protein DivIC PF04977.15 CDJ50061.1 - 7.2 6.5 26.9 0.83 9.5 10.8 2.2 2 0 0 2 2 2 0 Septum formation initiator CCDC117 PF15810.5 CDJ50061.1 - 7.2 6.9 12.2 0.43 10.9 3.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 117 DUF4199 PF13858.6 CDJ50061.1 - 8.3 6.8 11.3 0.37 11.2 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) RIC3 PF15361.6 CDJ50061.1 - 8.5 6.8 8.9 34 4.8 8.9 1.8 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 OATP PF03137.20 CDJ50061.1 - 8.6 4.5 9.9 0.82 7.9 2.2 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PIG-S PF10510.9 CDJ50064.1 - 8.6e-13 48.0 1.4 2.3e-05 23.5 0.0 3.8 4 0 0 4 4 4 3 Phosphatidylinositol-glycan biosynthesis class S protein YjbH PF06082.11 CDJ50065.1 - 8.2 5.1 13.5 9.4 4.9 13.5 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH HTH_23 PF13384.6 CDJ50066.1 - 0.00039 20.1 0.1 0.0039 16.9 0.1 2.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ50066.1 - 0.0067 16.5 0.3 0.0067 16.5 0.3 5.5 4 0 0 4 4 4 1 Helix-turn-helix domain SPX PF03105.19 CDJ50067.1 - 0.42 10.5 16.0 0.45 10.4 16.0 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CDJ50067.1 - 5.8 5.3 23.7 7.3 5.0 23.7 1.2 1 0 0 1 1 1 0 Macoilin family Dehydrin PF00257.19 CDJ50068.1 - 0.0023 18.5 1.0 0.0023 18.5 1.0 8.2 8 3 0 9 9 9 1 Dehydrin Spt20 PF12090.8 CDJ50070.1 - 0.042 13.5 26.1 0.062 12.9 26.1 1.3 1 0 0 1 1 1 0 Spt20 family Nrap_D3 PF17404.2 CDJ50070.1 - 0.081 13.0 2.5 0.13 12.4 2.5 1.3 1 0 0 1 1 1 0 Nrap protein domain 3 Shadoo PF14999.6 CDJ50070.1 - 0.1 12.7 0.6 0.1 12.7 0.6 4.6 2 1 1 3 3 1 0 Shadow of prion protein, neuroprotective NST1 PF13945.6 CDJ50070.1 - 0.13 12.4 10.1 0.17 12.0 10.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator EIF4E-T PF10477.9 CDJ50070.1 - 0.17 10.7 10.7 0.2 10.5 10.7 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Pex14_N PF04695.13 CDJ50070.1 - 0.21 12.2 33.2 0.069 13.8 23.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SKA1 PF07160.12 CDJ50070.1 - 0.34 10.7 8.9 0.44 10.4 8.9 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 PAT1 PF09770.9 CDJ50070.1 - 0.38 9.0 24.5 0.45 8.7 24.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tam41_Mmp37 PF09139.11 CDJ50070.1 - 0.42 10.0 7.6 0.55 9.6 7.6 1.2 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Ndc1_Nup PF09531.10 CDJ50070.1 - 1.1 7.9 17.5 1.2 7.8 17.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1980 PF09323.10 CDJ50070.1 - 1.5 8.7 6.4 2.3 8.1 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF572 PF04502.13 CDJ50070.1 - 2.1 7.9 9.4 2.2 7.8 9.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Lin-8 PF03353.15 CDJ50070.1 - 4.2 6.8 11.9 4.8 6.7 11.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 CDJ50070.1 - 5.7 3.9 12.1 5.6 3.9 12.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5521 PF17659.1 CDJ50070.1 - 7.9 4.2 15.0 11 3.7 15.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Neur_chan_memb PF02932.16 CDJ50070.1 - 9.8 6.1 7.7 12 5.8 7.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1980 PF09323.10 CDJ50071.1 - 0.0005 20.0 1.4 0.0005 20.0 1.4 3.2 2 1 0 2 2 1 1 Domain of unknown function (DUF1980) SPX PF03105.19 CDJ50071.1 - 0.0075 16.2 45.0 0.052 13.5 11.6 2.1 2 0 0 2 2 2 2 SPX domain DUF4834 PF16118.5 CDJ50071.1 - 0.031 15.2 3.6 0.031 15.2 3.6 3.3 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) Cwf_Cwc_15 PF04889.12 CDJ50071.1 - 0.13 12.0 25.5 0.8 9.4 4.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Neur_chan_memb PF02932.16 CDJ50071.1 - 0.15 12.1 18.7 0.35 10.9 0.2 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Miga PF10265.9 CDJ50071.1 - 0.26 10.2 36.8 0.1 11.5 16.6 2.2 2 0 0 2 2 2 0 Mitoguardin Pinin_SDK_memA PF04696.13 CDJ50071.1 - 0.57 10.2 25.2 0.38 10.8 13.9 2.3 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Ecl1 PF12855.7 CDJ50071.1 - 2.1 9.5 53.2 1.8 9.7 22.1 2.4 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins V_ATPase_I PF01496.19 CDJ50071.1 - 2.2 6.1 19.8 0.061 11.3 0.2 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Spt20 PF12090.8 CDJ50071.1 - 3.5 7.2 64.1 5.6 6.5 36.3 2.3 2 0 0 2 2 2 0 Spt20 family GREB1 PF15782.5 CDJ50071.1 - 4.3 4.3 47.4 1 6.4 25.1 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer DUF3801 PF12687.7 CDJ50071.1 - 7.5 6.6 25.7 0.32 11.0 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Macoilin PF09726.9 CDJ50071.1 - 8.8 4.7 54.2 0.013 14.1 19.7 2.2 2 0 0 2 2 2 0 Macoilin family BAF1_ABF1 PF04684.13 CDJ50071.1 - 9.9 5.1 39.0 2 7.3 9.3 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor AAA_2 PF07724.14 CDJ50072.1 - 1.8e-30 106.3 0.0 1.9e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CDJ50072.1 - 8.2e-08 32.3 0.0 8.5e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sporozoite_P67 PF05642.11 CDJ50073.1 - 0.00014 20.1 9.8 0.00014 20.1 9.8 1.9 2 0 0 2 2 1 1 Sporozoite P67 surface antigen DUF4821 PF16092.5 CDJ50073.1 - 0.0023 17.6 4.1 0.15 11.6 0.3 3.2 3 1 0 3 3 3 2 Domain of unknown function (DUF4821) SUIM_assoc PF16619.5 CDJ50073.1 - 0.012 15.7 14.2 0.012 15.7 14.2 6.5 4 2 0 4 4 1 0 Unstructured region C-term to UIM in Ataxin3 AF-4 PF05110.13 CDJ50073.1 - 0.071 11.2 54.0 0.066 11.3 34.3 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Hamartin PF04388.12 CDJ50073.1 - 0.19 10.4 40.3 0.11 11.1 23.0 2.0 2 0 0 2 2 2 0 Hamartin protein RAP1 PF07218.11 CDJ50073.1 - 0.37 9.0 14.4 0.6 8.3 14.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BAF1_ABF1 PF04684.13 CDJ50073.1 - 0.44 9.5 37.8 0.84 8.6 20.5 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF4048 PF13257.6 CDJ50073.1 - 0.94 9.3 44.6 1.9 8.3 5.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4048) SR-25 PF10500.9 CDJ50073.1 - 0.98 9.0 67.6 0.76 9.3 13.1 3.2 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein WBP-1 PF11669.8 CDJ50073.1 - 3.2 8.4 20.8 9.6 6.9 2.0 3.7 3 0 0 3 3 3 0 WW domain-binding protein 1 FYDLN_acid PF09538.10 CDJ50073.1 - 5.2 7.8 23.3 18 6.0 0.8 3.8 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF1645 PF07816.11 CDJ50073.1 - 5.6 7.5 39.6 0.16 12.5 16.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) DUF2722 PF10846.8 CDJ50074.1 - 7.8e-06 25.1 12.0 2.8e-05 23.3 5.8 6.2 5 1 1 6 6 6 3 Protein of unknown function (DUF2722) Exo_endo_phos PF03372.23 CDJ50074.1 - 0.0039 16.7 2.1 3.1 7.3 0.3 3.7 3 1 0 3 3 3 2 Endonuclease/Exonuclease/phosphatase family DEAD PF00270.29 CDJ50075.1 - 3.9e-25 88.6 0.0 3.2e-20 72.6 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase CMS1 PF14617.6 CDJ50075.1 - 0.0047 16.3 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF4703 PF15775.5 CDJ50075.1 - 0.024 14.4 2.0 0.034 13.9 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) RSF PF14876.6 CDJ50075.1 - 0.04 12.9 0.6 0.052 12.5 0.6 1.1 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator AAA_22 PF13401.6 CDJ50075.1 - 0.12 12.7 2.9 0.38 11.0 0.4 2.6 2 1 1 3 3 3 0 AAA domain UTP25 PF06862.12 CDJ50075.1 - 0.23 10.2 1.8 3.6 6.2 0.2 2.1 1 1 1 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CAF1 PF04857.20 CDJ50077.1 - 2.8e-05 23.5 1.2 3.7e-05 23.1 1.2 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease Connexin PF00029.19 CDJ50077.1 - 0.0086 15.9 1.1 3.5 7.3 0.9 2.1 2 0 0 2 2 2 2 Connexin Sec16 PF12932.7 CDJ50077.1 - 0.011 16.4 5.2 0.53 10.9 0.1 2.3 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region R_equi_Vir PF05526.11 CDJ50077.1 - 0.013 15.4 16.5 0.043 13.7 1.0 2.2 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein EIIBC-GUT_N PF03612.14 CDJ50077.1 - 0.04 13.7 6.4 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus CPSF100_C PF13299.6 CDJ50077.1 - 0.04 14.1 10.4 1.5 9.0 5.5 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal IHABP4_N PF16174.5 CDJ50077.1 - 0.079 13.6 19.1 0.81 10.3 11.6 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Peptidase_S49_N PF08496.10 CDJ50077.1 - 0.09 12.8 9.5 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4834 PF16118.5 CDJ50077.1 - 0.12 13.4 8.8 0.35 11.9 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 CDJ50077.1 - 0.15 12.4 7.6 2.2 8.6 0.6 2.2 2 0 0 2 2 2 0 Orf78 (ac78) BAF1_ABF1 PF04684.13 CDJ50077.1 - 0.25 10.4 12.1 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor SpoIIP PF07454.11 CDJ50077.1 - 0.28 10.6 8.2 1.8 7.9 2.6 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDJ50077.1 - 0.59 9.9 12.2 0.22 11.3 4.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Peroxin-13_N PF04088.13 CDJ50077.1 - 0.65 10.3 4.9 5.1 7.4 0.1 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region FAM60A PF15396.6 CDJ50077.1 - 0.87 9.6 7.0 3.3 7.7 2.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A CENP-O PF09496.10 CDJ50077.1 - 1.2 9.1 10.1 0.13 12.3 1.6 2.2 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component AIF_C PF14721.6 CDJ50077.1 - 1.9 8.9 9.1 5.6 7.3 2.5 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term OmpH PF03938.14 CDJ50077.1 - 2 8.7 37.7 0.092 13.1 7.9 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Suf PF05843.14 CDJ50077.1 - 2 8.3 17.3 2.9 7.8 5.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) U1snRNP70_N PF12220.8 CDJ50077.1 - 2.1 9.0 12.4 2.6 8.7 3.3 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4288 PF14119.6 CDJ50077.1 - 2.8 8.4 12.0 1.9 8.9 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) GET2 PF08690.10 CDJ50077.1 - 2.9 7.5 17.0 1.5 8.4 5.1 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 RPA43_OB PF17875.1 CDJ50077.1 - 3.1 8.4 7.6 17 6.1 0.1 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Exonuc_VII_L PF02601.15 CDJ50077.1 - 3.6 7.1 17.2 0.44 10.1 0.2 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA_23 PF13476.6 CDJ50077.1 - 6.5 7.2 20.3 0.9 10.0 4.0 2.1 2 0 0 2 2 2 0 AAA domain Cid2 PF09774.9 CDJ50077.1 - 6.7 7.1 16.2 6.8 7.1 2.9 2.2 2 0 0 2 2 2 0 Caffeine-induced death protein 2 RNA_pol_Rpc4 PF05132.14 CDJ50077.1 - 7.2 7.0 14.3 2 8.8 6.8 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF3169 PF11368.8 CDJ50077.1 - 7.5 6.0 5.6 31 4.0 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) CTU2 PF10288.9 CDJ50077.1 - 7.7 6.8 12.0 11 6.3 1.1 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 tRNA_synt_1c_R2 PF04557.15 CDJ50077.1 - 8.2 7.4 15.8 9.3 7.3 0.0 2.7 2 1 1 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF2203 PF09969.9 CDJ50077.1 - 8.4 7.1 12.0 3.5 8.4 0.8 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2232 PF09991.9 CDJ50077.1 - 9.3 5.3 7.9 1.6 7.9 0.7 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) CIAPIN1 PF05093.13 CDJ50077.1 - 9.5 6.8 10.2 8.9 6.9 1.0 2.3 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3464 PF11947.8 CDJ50077.1 - 9.9 5.9 12.0 7.1 6.4 0.7 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Dpy-30 PF05186.13 CDJ50079.1 - 4.2e-07 29.6 0.1 1e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Dpy-30 motif V_ATPase_I PF01496.19 CDJ50079.1 - 0.33 8.8 6.3 0.55 8.1 6.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAGA_bind PF06217.12 CDJ50079.1 - 4.8 7.4 7.2 12 6.1 5.8 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Kin17_mid PF10357.9 CDJ50079.1 - 5.2 7.0 12.0 7.1 6.6 5.5 2.8 3 0 0 3 3 3 0 Domain of Kin17 curved DNA-binding protein Trypsin_2 PF13365.6 CDJ50080.1 - 4.8e-12 47.0 0.2 9.4e-12 46.1 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 CDJ50080.1 - 2.4e-07 30.5 0.3 5.2e-07 29.4 0.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ50080.1 - 4.1e-06 27.0 0.0 8.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ50080.1 - 0.0003 21.0 0.1 0.0041 17.4 0.0 2.4 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 CDJ50080.1 - 0.074 12.9 0.1 0.25 11.1 0.1 1.8 1 1 0 1 1 1 0 Trypsin Peptidase_S29 PF02907.15 CDJ50080.1 - 0.094 12.4 0.4 0.2 11.4 0.1 1.6 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease DUF3969 PF13108.6 CDJ50082.1 - 0.021 14.8 3.1 0.022 14.8 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) Longin PF13774.6 CDJ50082.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain Phage_AlpA PF05930.12 CDJ50083.1 - 0.013 15.4 0.0 0.48 10.3 0.0 2.4 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) ROF PF07073.12 CDJ50085.1 - 1.9 8.7 6.6 1.2 9.3 3.0 2.6 2 0 0 2 2 2 0 Modulator of Rho-dependent transcription termination (ROF) Ribosomal_L14 PF00238.19 CDJ50086.1 - 6.2e-16 58.6 0.0 1.1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RskA PF10099.9 CDJ50086.1 - 0.001 19.4 13.1 0.001 19.4 13.1 2.4 1 1 1 2 2 2 1 Anti-sigma-K factor rskA SSP160 PF06933.11 CDJ50086.1 - 0.029 12.6 8.6 0.034 12.4 8.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4834 PF16118.5 CDJ50086.1 - 0.21 12.6 0.2 0.21 12.6 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) EPL1 PF10513.9 CDJ50086.1 - 0.52 10.7 15.7 1.1 9.7 7.4 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Sporozoite_P67 PF05642.11 CDJ50086.1 - 0.66 8.0 7.5 1.2 7.1 7.4 1.5 1 1 0 1 1 1 0 Sporozoite P67 surface antigen FSA_C PF10479.9 CDJ50086.1 - 1.2 7.1 8.1 1.7 6.7 8.1 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Med15 PF09606.10 CDJ50086.1 - 3 6.4 43.5 3.7 6.1 43.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_UL74 PF07982.12 CDJ50086.1 - 3.5 6.5 5.3 6.2 5.7 5.3 1.4 1 0 0 1 1 1 0 Herpes UL74 glycoproteins SseC PF04888.12 CDJ50087.1 - 0.0019 17.9 1.3 0.0019 17.9 1.3 10.4 7 3 2 10 10 10 2 Secretion system effector C (SseC) like family NAM-associated PF14303.6 CDJ50087.1 - 0.37 11.5 0.0 0.37 11.5 0.0 8.8 2 1 3 7 7 7 0 No apical meristem-associated C-terminal domain YabA PF06156.13 CDJ50088.1 - 0.16 12.6 14.3 0.17 12.5 14.3 1.1 1 0 0 1 1 1 0 Initiation control protein YabA DUF1664 PF07889.12 CDJ50088.1 - 0.16 12.0 13.9 0.19 11.8 13.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3552 PF12072.8 CDJ50088.1 - 0.17 11.2 26.4 0.19 11.1 26.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Afi1 PF07792.12 CDJ50088.1 - 0.85 10.1 12.0 0.88 10.0 12.0 1.0 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FAM176 PF14851.6 CDJ50088.1 - 1.8 8.2 7.1 2 8.1 7.1 1.1 1 0 0 1 1 1 0 FAM176 family DUF4407 PF14362.6 CDJ50088.1 - 4 6.7 18.0 4.8 6.4 18.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 CDJ50088.1 - 5.8 6.4 22.7 6.4 6.3 22.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Kei1 PF08552.11 CDJ50088.1 - 7.8 6.3 7.2 8.3 6.2 7.2 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 V_ATPase_I PF01496.19 CDJ50088.1 - 8.1 4.2 17.0 9.7 4.0 17.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRP36 PF06102.12 CDJ50088.1 - 9.1 6.2 20.0 11 6.0 20.0 1.0 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DDE_Tnp_ISL3 PF01610.17 CDJ50088.1 - 9.7 5.8 12.3 10 5.7 12.3 1.0 1 0 0 1 1 1 0 Transposase SPX PF03105.19 CDJ50089.1 - 0.0051 16.8 1.2 0.0051 16.8 1.2 3.2 2 1 1 3 3 3 2 SPX domain AAA_23 PF13476.6 CDJ50089.1 - 2.9 8.4 32.6 3.3 8.2 8.0 3.4 3 0 0 3 3 3 0 AAA domain Spt20 PF12090.8 CDJ50090.1 - 0.00022 20.9 2.6 0.00036 20.2 2.6 1.3 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ50090.1 - 0.0031 16.5 0.2 0.0036 16.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF5421 PF17458.2 CDJ50090.1 - 0.042 13.2 0.7 0.068 12.6 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Rtf2 PF04641.12 CDJ50090.1 - 0.096 12.0 1.3 1.4 8.3 0.1 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger SUIM_assoc PF16619.5 CDJ50090.1 - 0.79 9.8 12.4 1.6 8.8 12.4 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CTU2 PF10288.9 CDJ50090.1 - 2.9 8.2 8.0 10 6.4 0.9 3.0 2 1 1 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 SseC PF04888.12 CDJ50092.1 - 0.0013 18.4 17.2 0.0013 18.4 17.2 4.9 4 1 0 4 4 4 1 Secretion system effector C (SseC) like family K_channel_TID PF07941.11 CDJ50093.1 - 0.025 15.0 3.1 0.025 15.0 3.1 3.1 2 1 1 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain HD_6 PF18019.1 CDJ50093.1 - 0.45 10.6 9.0 0.56 10.3 9.0 1.1 1 0 0 1 1 1 0 HD domain DUF4192 PF13830.6 CDJ50093.1 - 0.85 9.6 10.4 0.1 12.7 5.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4192) Methuselah_N PF06652.12 CDJ50093.1 - 6.8 6.6 9.6 0.42 10.5 3.3 1.8 1 1 1 2 2 2 0 Methuselah N-terminus Vma12 PF11712.8 CDJ50093.1 - 7.7 6.6 8.6 2.2 8.4 2.0 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2368 PF10166.9 CDJ50093.1 - 7.9 6.1 22.6 0.85 9.2 2.3 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) DHHC PF01529.20 CDJ50094.1 - 5.5e-08 33.0 5.8 0.0013 18.8 0.2 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase HGD-D PF06050.13 CDJ50094.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component FAP PF07174.11 CDJ50094.1 - 3.6 7.0 29.8 5.7 6.3 29.8 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF4746 PF15928.5 CDJ50095.1 - 0.012 15.1 17.3 0.013 14.9 17.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Gti1_Pac2 PF09729.9 CDJ50095.1 - 0.25 11.4 22.4 0.36 10.9 22.4 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Presenilin PF01080.17 CDJ50095.1 - 0.44 9.3 36.6 0.49 9.1 36.6 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CDJ50095.1 - 0.54 8.5 25.6 0.61 8.3 25.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3295 PF11702.8 CDJ50095.1 - 0.55 9.5 26.8 0.66 9.3 26.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Pox_Ag35 PF03286.14 CDJ50095.1 - 1.4 8.7 16.5 1.7 8.4 16.5 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MCM_bind PF09739.9 CDJ50095.1 - 1.8 6.9 25.5 2.1 6.7 25.5 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Endostatin PF06482.11 CDJ50095.1 - 1.9 7.8 33.0 2.4 7.5 33.0 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin BORG_CEP PF14957.6 CDJ50095.1 - 4.4 8.5 22.3 6.3 8.0 22.3 1.3 1 0 0 1 1 1 0 Cdc42 effector AF-4 PF05110.13 CDJ50095.1 - 4.8 5.1 37.0 5.6 4.9 37.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RR_TM4-6 PF06459.12 CDJ50095.1 - 4.9 6.9 34.4 5.8 6.7 34.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Plasmodium_Vir PF05795.11 CDJ50095.1 - 5.3 6.4 17.7 6.7 6.0 17.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.16 CDJ50095.1 - 5.9 6.9 26.1 7.5 6.5 26.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 CDJ50095.1 - 7.5 4.5 29.7 8.4 4.4 29.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VIT1 PF01988.19 CDJ50095.1 - 8.2 6.2 17.0 9.7 6.0 17.0 1.0 1 0 0 1 1 1 0 VIT family Ferlin_C PF16165.5 CDJ50096.1 - 1.4 8.9 4.0 7.3 6.5 1.6 3.4 3 0 0 3 3 3 0 Ferlin C-terminus SR-25 PF10500.9 CDJ50097.1 - 2.9e-05 23.8 8.6 2.9e-05 23.8 8.6 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein NUC153 PF08159.12 CDJ50097.1 - 0.0006 19.6 0.1 0.0014 18.4 0.1 1.7 1 0 0 1 1 1 1 NUC153 domain DUF5421 PF17458.2 CDJ50097.1 - 0.061 12.7 2.7 0.11 11.8 2.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5421) NuDC PF16273.5 CDJ50097.1 - 0.098 13.2 1.1 0.098 13.2 1.1 2.6 2 0 0 2 2 2 0 Nuclear distribution C domain DUF1738 PF08401.11 CDJ50097.1 - 0.38 10.9 4.6 7.4 6.7 1.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1738) DUF4228 PF14009.6 CDJ50097.1 - 1.2 9.6 7.2 0.19 12.1 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) FAM199X PF15814.5 CDJ50097.1 - 1.9 7.5 16.0 2.2 7.3 14.4 1.9 1 1 1 2 2 2 0 Protein family FAM199X CagX PF03524.15 CDJ50097.1 - 4.9 6.8 6.7 13 5.4 0.0 2.7 3 0 0 3 3 3 0 Conjugal transfer protein SIMPL PF04402.14 CDJ50097.1 - 9.1 6.7 23.4 0.038 14.5 6.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF541) DUF2852 PF11014.8 CDJ50098.1 - 0.0072 16.5 0.1 0.0087 16.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2852) NARP1 PF12569.8 CDJ50098.1 - 0.02 13.9 8.6 0.024 13.6 8.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FPN1 PF06963.12 CDJ50098.1 - 0.036 12.6 3.2 0.034 12.7 3.2 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) TMEM65 PF10507.9 CDJ50098.1 - 0.04 13.9 0.5 0.053 13.5 0.5 1.4 1 1 0 1 1 1 0 Transmembrane protein 65 CobT PF06213.12 CDJ50098.1 - 0.041 13.3 10.6 0.044 13.2 10.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Folate_carrier PF01770.18 CDJ50098.1 - 0.042 12.6 3.2 0.053 12.3 3.2 1.0 1 0 0 1 1 1 0 Reduced folate carrier Spt20 PF12090.8 CDJ50098.1 - 0.06 12.9 26.1 0.065 12.8 26.1 1.2 1 0 0 1 1 1 0 Spt20 family AIF_C PF14721.6 CDJ50098.1 - 0.11 12.9 4.2 0.14 12.5 4.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Presenilin PF01080.17 CDJ50098.1 - 0.14 10.9 7.2 0.14 10.9 7.2 1.0 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ50098.1 - 0.15 11.0 14.4 0.16 10.9 14.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) WRNPLPNID PF15017.6 CDJ50098.1 - 0.17 12.7 6.3 0.28 12.1 6.3 1.4 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF4834 PF16118.5 CDJ50098.1 - 0.21 12.6 9.5 0.28 12.1 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) OATP PF03137.20 CDJ50098.1 - 0.22 9.8 2.6 0.25 9.6 2.6 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family V_ATPase_I PF01496.19 CDJ50098.1 - 0.23 9.3 7.2 0.23 9.3 7.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.17 CDJ50098.1 - 0.29 11.2 5.3 0.32 11.1 5.3 1.2 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.13 CDJ50098.1 - 0.31 10.8 7.7 0.37 10.5 7.7 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SpoIIP PF07454.11 CDJ50098.1 - 0.37 10.2 8.7 0.4 10.1 8.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TERB2 PF15101.6 CDJ50098.1 - 0.37 10.8 10.5 0.35 10.9 10.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Neur_chan_memb PF02932.16 CDJ50098.1 - 0.42 10.6 4.5 0.43 10.6 4.5 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Orf78 PF06024.12 CDJ50098.1 - 0.57 10.5 5.0 0.79 10.1 5.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) DUF4175 PF13779.6 CDJ50098.1 - 0.66 7.8 24.4 0.66 7.8 24.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Baculo_PP31 PF05311.11 CDJ50098.1 - 0.73 9.3 7.6 0.74 9.3 7.6 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Connexin PF00029.19 CDJ50098.1 - 0.81 9.4 6.0 0.81 9.4 6.0 1.1 1 0 0 1 1 1 0 Connexin UPF0560 PF10577.9 CDJ50098.1 - 1.5 7.2 14.0 1.5 7.2 14.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Suf PF05843.14 CDJ50098.1 - 1.7 8.5 12.6 1.9 8.4 12.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ50098.1 - 2.1 8.3 26.3 2.2 8.2 26.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Eapp_C PF10238.9 CDJ50098.1 - 2.3 8.3 11.6 3.3 7.8 11.6 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein SprA-related PF12118.8 CDJ50098.1 - 2.4 7.2 21.2 2.8 7.0 21.2 1.1 1 0 0 1 1 1 0 SprA-related family CLN3 PF02487.17 CDJ50098.1 - 3 6.8 5.7 3.1 6.7 5.7 1.1 1 0 0 1 1 1 0 CLN3 protein MMR1 PF08505.10 CDJ50098.1 - 3.1 8.0 13.4 3.2 8.0 13.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Serinc PF03348.15 CDJ50098.1 - 5.8 5.7 4.9 5.5 5.8 4.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Coilin_N PF15862.5 CDJ50098.1 - 6.1 6.7 12.2 8.6 6.2 12.2 1.2 1 0 0 1 1 1 0 Coilin N-terminus RskA PF10099.9 CDJ50099.1 - 0.15 12.4 17.8 0.062 13.6 8.4 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA GREB1 PF15782.5 CDJ50099.1 - 0.76 6.8 28.4 0.91 6.6 28.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CDJ50100.1 - 0.00088 19.4 17.0 0.00098 19.2 17.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4148 PF13663.6 CDJ50100.1 - 0.0049 17.0 8.4 0.39 10.9 4.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4148) DUF2722 PF10846.8 CDJ50100.1 - 0.0058 15.6 13.5 0.0064 15.5 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Shadoo PF14999.6 CDJ50100.1 - 0.012 15.7 15.3 0.052 13.6 6.5 2.5 3 0 0 3 3 2 0 Shadow of prion protein, neuroprotective Androgen_recep PF02166.16 CDJ50100.1 - 0.075 11.9 33.7 0.17 10.7 33.7 1.6 1 1 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 CDJ50100.1 - 0.31 10.6 21.6 0.41 10.2 21.6 1.1 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ50100.1 - 0.49 10.7 26.7 0.68 10.2 14.7 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Miga PF10265.9 CDJ50100.1 - 0.49 9.3 2.8 0.61 9.0 2.8 1.0 1 0 0 1 1 1 0 Mitoguardin Suf PF05843.14 CDJ50100.1 - 0.91 9.5 8.7 0.94 9.4 8.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ50100.1 - 1.1 8.0 8.7 1.2 7.8 8.7 1.1 1 0 0 1 1 1 0 Presenilin HA2 PF04408.23 CDJ50100.1 - 1.2 9.4 4.6 3.2 8.1 3.4 1.9 2 0 0 2 2 2 0 Helicase associated domain (HA2) TERB2 PF15101.6 CDJ50100.1 - 1.3 9.0 7.9 1.8 8.6 7.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PAT1 PF09770.9 CDJ50100.1 - 1.9 6.7 14.3 1.9 6.7 14.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 CDJ50100.1 - 2.2 7.2 9.6 2.5 7.0 9.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ50100.1 - 2.9 7.9 7.1 3.8 7.5 7.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Adeno_PIX PF03955.14 CDJ50100.1 - 3.4 7.9 10.4 1.3 9.3 0.7 2.4 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Ribosomal_60s PF00428.19 CDJ50100.1 - 5.8 7.6 25.8 0.57 10.8 6.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Porin_4 PF13609.6 CDJ50100.1 - 7.1 6.3 10.4 6.3 6.4 1.1 2.1 2 0 0 2 2 2 0 Gram-negative porin Menin PF05053.13 CDJ50100.1 - 7.3 4.8 9.7 10 4.3 9.7 1.2 1 0 0 1 1 1 0 Menin DUF1003 PF06210.11 CDJ50100.1 - 9.9 6.3 7.7 18 5.5 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) 5_nucleotid_C PF02872.18 CDJ50101.1 - 6.9e-37 127.1 0.0 2.1e-36 125.5 0.0 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CDJ50101.1 - 7e-06 26.7 0.5 4.4e-05 24.1 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3251 PF11622.8 CDJ50102.1 - 0.087 12.5 0.4 0.19 11.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) LRR_4 PF12799.7 CDJ50102.1 - 0.16 12.4 0.9 14 6.2 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Allexi_40kDa PF05549.11 CDJ50102.1 - 0.18 11.3 3.6 0.37 10.3 3.6 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein FapA PF03961.13 CDJ50102.1 - 0.65 8.5 2.0 1 7.9 2.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Not3 PF04065.15 CDJ50102.1 - 2.7 7.3 10.3 5.4 6.4 10.3 1.4 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component CCDC-167 PF15188.6 CDJ50102.1 - 5.1 7.5 6.9 0.53 10.7 1.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FA_desaturase PF00487.24 CDJ50103.1 - 7.5e-09 35.8 18.8 7.5e-09 35.8 18.8 3.7 3 1 1 4 4 4 2 Fatty acid desaturase ELO PF01151.18 CDJ50103.1 - 0.1 12.1 5.3 0.038 13.5 1.3 2.3 2 0 0 2 2 2 0 GNS1/SUR4 family DUF569 PF04601.13 CDJ50103.1 - 0.16 11.6 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF569) Ank_2 PF12796.7 CDJ50104.1 - 1.9e-38 130.9 0.2 2.9e-13 50.2 0.1 5.5 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ50104.1 - 4.6e-29 100.4 0.1 1.4e-05 25.6 0.0 7.3 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ50104.1 - 2.5e-27 94.5 3.7 0.00013 22.2 0.0 7.2 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ50104.1 - 3.3e-27 91.5 0.3 0.032 14.8 0.0 9.8 10 0 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 CDJ50104.1 - 1.9e-19 69.1 1.4 0.08 13.4 0.0 9.9 11 0 0 11 11 11 6 Ankyrin repeat RseA_C PF03873.13 CDJ50105.1 - 0.049 13.9 0.7 14 6.0 0.1 2.7 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain CLAG PF03805.13 CDJ50105.1 - 0.12 9.9 0.0 0.38 8.3 0.0 1.7 1 1 0 1 1 1 0 Cytoadherence-linked asexual protein AMA-1 PF02430.15 CDJ50106.1 - 3.7e-17 62.5 0.7 1.1e-16 60.9 0.6 1.7 2 0 0 2 2 2 1 Apical membrane antigen 1 DOT1 PF08123.13 CDJ50107.1 - 4.8e-05 23.0 0.0 8.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 S4 PF01479.25 CDJ50108.1 - 1.7e-12 46.8 2.5 2.2e-12 46.5 0.4 2.3 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 CDJ50108.1 - 4e-06 27.7 1.0 6.4e-06 27.0 0.7 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain MFS_1 PF07690.16 CDJ50109.1 - 1.6e-08 33.9 45.9 1.9e-08 33.7 38.3 3.6 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDJ50109.1 - 1.2e-05 23.8 10.7 0.00033 19.1 0.0 3.5 2 2 1 3 3 2 2 Organic Anion Transporter Polypeptide (OATP) family Vut_1 PF02592.15 CDJ50109.1 - 0.0017 18.7 0.3 0.0017 18.7 0.3 2.9 3 1 0 4 4 3 1 Putative vitamin uptake transporter DUF4667 PF15700.5 CDJ50109.1 - 0.0087 16.2 3.1 0.029 14.5 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4667) Ctr PF04145.15 CDJ50109.1 - 0.069 13.8 0.6 20 5.8 0.2 2.8 2 0 0 2 2 2 0 Ctr copper transporter family PepSY_TM PF03929.16 CDJ50109.1 - 0.099 12.3 8.1 0.74 9.4 1.0 3.7 2 1 1 3 3 3 0 PepSY-associated TM region TFIIA PF03153.13 CDJ50109.1 - 0.18 11.8 21.8 0.25 11.3 3.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit G0-G1_switch_2 PF15103.6 CDJ50109.1 - 0.33 11.4 3.9 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 Phage_holin_2_3 PF16080.5 CDJ50109.1 - 0.37 10.6 0.0 0.37 10.6 0.0 3.0 3 0 0 3 3 3 0 Bacteriophage holin family HP1 CPSF100_C PF13299.6 CDJ50109.1 - 0.64 10.2 3.7 6.6 6.9 0.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EI24 PF07264.11 CDJ50109.1 - 0.92 9.7 0.0 0.92 9.7 0.0 3.5 3 1 0 3 3 2 0 Etoposide-induced protein 2.4 (EI24) DUF3391 PF11871.8 CDJ50109.1 - 1.3 9.6 9.5 4.8 7.7 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF2722 PF10846.8 CDJ50109.1 - 1.5 7.7 25.5 0.12 11.3 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ50109.1 - 3.7 8.6 9.1 2.6 9.1 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ORC_WH_C PF18137.1 CDJ50109.1 - 6.1 6.9 7.0 3.2 7.8 0.2 2.2 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal CTU2 PF10288.9 CDJ50109.1 - 6.4 7.1 6.5 12 6.2 0.2 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 UCH PF00443.29 CDJ50110.1 - 1.4e-31 109.9 0.0 6.8e-29 101.1 0.0 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ50110.1 - 8e-14 52.0 12.2 4.6e-11 42.9 0.0 4.3 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Proteasome PF00227.26 CDJ50111.1 - 8.5e-25 87.3 0.1 1.1e-24 87.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Tafi-CsgC PF10610.9 CDJ50111.1 - 0.055 13.7 0.0 0.072 13.3 0.0 1.2 1 0 0 1 1 1 0 Thin aggregative fimbriae synthesis protein Virulence_fact PF13769.6 CDJ50111.1 - 0.061 13.6 0.8 0.074 13.3 0.8 1.1 1 0 0 1 1 1 0 Virulence factor DUF4194 PF13835.6 CDJ50111.1 - 0.066 12.9 0.2 0.08 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) Neisseria_TspB PF05616.13 CDJ50112.1 - 1.8 7.0 8.7 2.9 6.3 8.7 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Mito_fiss_reg PF05308.11 CDJ50113.1 - 0.028 14.5 6.3 0.03 14.4 6.3 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CDC27 PF09507.10 CDJ50113.1 - 0.38 10.1 11.7 0.38 10.1 11.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Spt20 PF12090.8 CDJ50113.1 - 0.79 9.3 15.4 0.78 9.3 15.4 1.1 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 CDJ50113.1 - 0.96 10.1 16.0 1.1 9.9 16.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ50113.1 - 1.7 8.6 20.9 1.7 8.5 20.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IHABP4_N PF16174.5 CDJ50113.1 - 4.2 7.9 14.7 5.3 7.6 14.7 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal R_equi_Vir PF05526.11 CDJ50113.1 - 4.3 7.2 6.3 4.9 7.0 6.3 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Presenilin PF01080.17 CDJ50113.1 - 8 5.1 7.0 7.6 5.2 7.0 1.0 1 0 0 1 1 1 0 Presenilin Presenilin PF01080.17 CDJ50114.1 - 2.6 6.7 10.8 3.3 6.4 10.8 1.1 1 0 0 1 1 1 0 Presenilin Presenilin PF01080.17 CDJ50115.1 - 0.00039 19.3 24.4 0.00039 19.3 24.4 4.0 2 1 0 2 2 2 1 Presenilin PAT1 PF09770.9 CDJ50115.1 - 8.7 4.5 71.6 1.6 6.9 44.7 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 zf-rbx1 PF12678.7 CDJ50116.1 - 2.1e-06 27.9 0.5 2.1e-06 27.9 0.5 3.0 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ50116.1 - 5.2e-06 26.2 0.2 5.2e-06 26.2 0.2 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ50116.1 - 7.7e-05 22.9 8.4 0.00013 22.2 1.5 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ50116.1 - 0.00072 19.4 1.6 0.00072 19.4 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ50116.1 - 0.0073 16.0 2.2 0.86 9.4 1.0 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CDJ50116.1 - 0.011 15.8 0.6 0.011 15.8 0.6 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger RskA PF10099.9 CDJ50116.1 - 0.036 14.3 0.1 0.036 14.3 0.1 8.0 1 1 3 5 5 4 0 Anti-sigma-K factor rskA zf-RING_UBOX PF13445.6 CDJ50116.1 - 0.061 13.4 1.1 0.33 11.0 0.3 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 CDJ50116.1 - 0.24 11.4 2.1 0.69 10.0 2.1 1.8 1 0 0 1 1 1 0 Zinc-finger SR-25 PF10500.9 CDJ50116.1 - 0.44 10.1 52.1 0.04 13.5 1.1 4.5 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein JAB PF01398.21 CDJ50116.1 - 0.47 10.4 0.0 0.47 10.4 0.0 3.0 3 1 0 3 3 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SDA1 PF05285.12 CDJ50116.1 - 2.4 7.5 31.2 1.3 8.4 9.5 2.9 2 1 0 2 2 2 0 SDA1 zf-RING_5 PF14634.6 CDJ50116.1 - 3.1 7.8 10.9 0.057 13.4 1.1 2.8 3 0 0 3 3 3 0 zinc-RING finger domain RINGv PF12906.7 CDJ50116.1 - 3.5 7.8 6.6 0.24 11.6 0.9 2.0 2 0 0 2 2 1 0 RING-variant domain Exostosin PF03016.15 CDJ50118.1 - 0.07 12.3 2.4 0.096 11.9 2.4 1.1 1 0 0 1 1 1 0 Exostosin family MRP-L20 PF12824.7 CDJ50118.1 - 0.24 11.6 11.9 0.52 10.4 11.9 1.8 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Nuc_deoxyri_tr2 PF15891.5 CDJ50118.1 - 0.37 11.1 5.1 0.16 12.3 1.5 2.1 1 1 1 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like SLC12 PF03522.15 CDJ50118.1 - 0.76 8.7 5.9 0.84 8.6 5.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ50118.1 - 1 8.9 12.6 1.6 8.2 12.6 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PIP5K PF01504.18 CDJ50118.1 - 1.3 8.2 5.2 2.2 7.5 5.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase V_ATPase_I PF01496.19 CDJ50118.1 - 1.4 6.8 7.4 2 6.2 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_hydro_cc PF11790.8 CDJ50118.1 - 1.6 8.3 9.3 4.1 6.9 9.3 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase catalytic core Hid1 PF12722.7 CDJ50118.1 - 1.7 6.6 12.1 2 6.4 12.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NLPC_P60 PF00877.19 CDJ50118.1 - 2.4 8.2 8.2 9.8 6.3 8.3 1.9 1 1 0 1 1 1 0 NlpC/P60 family DUF4770 PF15994.5 CDJ50118.1 - 4.1 7.6 12.8 4.5 7.5 4.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) PAT1 PF09770.9 CDJ50118.1 - 5.4 5.2 25.2 6.8 4.8 25.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TYW3 PF02676.14 CDJ50118.1 - 8.5 5.7 7.5 5 6.4 5.7 1.7 1 1 1 2 2 2 0 Methyltransferase TYW3 WD40 PF00400.32 CDJ50119.1 - 2.7e-05 24.8 14.5 0.57 11.1 0.1 9.2 9 0 0 9 9 9 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ50119.1 - 0.00011 22.4 0.0 15 5.9 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NUDIX_2 PF13869.6 CDJ50120.1 - 1.6e-55 187.6 0.0 2.1e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase FtsJ PF01728.19 CDJ50122.1 - 2.8e-53 180.7 0.0 3.8e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ribosomal_L34e PF01199.18 CDJ50122.1 - 6e-14 52.1 0.5 2.4e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L34e Methyltransf_31 PF13847.6 CDJ50122.1 - 0.0053 16.6 0.0 0.21 11.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ50122.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NSP16 PF06460.12 CDJ50122.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Coronavirus NSP16 zf-3CxxC_2 PF17180.4 CDJ50122.1 - 0.15 12.8 2.1 0.28 12.0 1.0 1.9 2 0 0 2 2 2 0 Zinc-binding domain AP2 PF00847.20 CDJ50123.1 - 1.4e-18 66.8 2.0 2.9e-12 46.6 0.1 2.7 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.6 CDJ50123.1 - 0.0015 18.8 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 AP2-coincident C-terminal DUF2722 PF10846.8 CDJ50124.1 - 0.00053 19.1 21.7 0.00053 19.1 21.7 4.0 3 1 0 3 3 2 1 Protein of unknown function (DUF2722) GT87 PF09594.10 CDJ50124.1 - 0.0018 18.1 7.2 0.19 11.4 0.9 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 87 DUF4401 PF14351.6 CDJ50124.1 - 0.0043 16.4 0.1 0.0055 16.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) DUF3180 PF11377.8 CDJ50124.1 - 0.014 15.6 14.7 0.31 11.2 7.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) RskA PF10099.9 CDJ50124.1 - 0.026 14.8 28.9 0.026 14.8 28.9 3.1 1 1 2 3 3 2 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ50124.1 - 0.24 11.0 55.7 0.31 10.6 19.2 2.5 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein DUF5305 PF17231.2 CDJ50124.1 - 0.27 10.6 1.2 1.4 8.3 0.0 2.4 1 1 0 2 2 2 0 Family of unknown function (DUF5305) CD20 PF04103.15 CDJ50124.1 - 0.49 10.5 17.9 0.29 11.2 0.6 3.2 1 1 2 3 3 3 0 CD20-like family FTR1 PF03239.14 CDJ50124.1 - 0.51 9.5 0.0 0.51 9.5 0.0 2.5 2 0 0 2 2 2 0 Iron permease FTR1 family EcsB PF05975.12 CDJ50124.1 - 0.6 8.9 2.7 5.7 5.7 0.2 2.0 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB DUF3169 PF11368.8 CDJ50124.1 - 0.83 9.1 7.6 3.4 7.1 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) DUF4179 PF13786.6 CDJ50124.1 - 2.6 8.6 21.4 0.1 13.1 1.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Trp_oprn_chp PF09534.10 CDJ50124.1 - 5 6.9 40.9 94 2.7 16.4 2.9 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pinin_SDK_memA PF04696.13 CDJ50124.1 - 6.2 6.9 62.4 0.16 12.0 12.3 3.1 3 0 0 3 3 3 0 pinin/SDK/memA/ protein conserved region PNISR PF15996.5 CDJ50125.1 - 0.0032 17.8 24.2 0.0032 17.8 24.2 2.3 2 0 0 2 2 2 1 Arginine/serine-rich protein PNISR DUF2052 PF09747.9 CDJ50125.1 - 0.073 13.2 43.3 0.24 11.5 24.8 2.2 1 1 1 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ50125.1 - 0.1 12.4 33.2 0.54 10.0 20.5 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 CDJ50125.1 - 0.19 11.9 33.7 0.15 12.2 17.3 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Pex14_N PF04695.13 CDJ50125.1 - 0.63 10.7 59.9 0.61 10.7 11.8 3.5 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PPL5 PF18168.1 CDJ50125.1 - 1.2 8.4 17.3 2.9 7.1 0.8 2.2 2 0 0 2 2 2 0 Prim-pol family 5 DUF4045 PF13254.6 CDJ50125.1 - 1.3 8.6 27.9 0.59 9.7 16.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) SRP-alpha_N PF04086.13 CDJ50125.1 - 1.5 8.7 31.5 2.4 8.0 20.5 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal SpoIIP PF07454.11 CDJ50125.1 - 2.5 7.5 30.2 0.51 9.8 15.3 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TCP PF03634.13 CDJ50125.1 - 5.1 7.6 30.7 6.8 7.2 5.3 2.3 2 0 0 2 2 2 0 TCP family transcription factor DUF4050 PF13259.6 CDJ50125.1 - 7.3 6.9 24.8 1.9 8.8 11.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Folliculin PF11704.8 CDJ50125.1 - 9.4 6.1 27.0 2.3 8.1 12.6 2.4 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Utp14 PF04615.13 CDJ50125.1 - 9.9 4.6 37.2 15 4.0 37.2 1.2 1 0 0 1 1 1 0 Utp14 protein DUF2722 PF10846.8 CDJ50128.1 - 0.0017 17.4 10.9 0.0017 17.4 10.9 9.1 8 1 1 9 9 9 4 Protein of unknown function (DUF2722) NARP1 PF12569.8 CDJ50128.1 - 0.0054 15.7 0.8 0.0054 15.7 0.8 6.5 7 2 1 8 8 8 1 NMDA receptor-regulated protein 1 Mannosyl_trans4 PF15971.5 CDJ50128.1 - 0.017 15.0 1.1 0.083 12.7 1.1 2.2 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase RXT2_N PF08595.11 CDJ50128.1 - 0.035 14.1 0.6 0.035 14.1 0.6 5.1 6 1 0 6 6 6 0 RXT2-like, N-terminal BAF250_C PF12031.8 CDJ50128.1 - 0.6 9.4 0.0 0.6 9.4 0.0 4.6 6 0 0 6 6 6 0 SWI/SNF-like complex subunit BAF250/Osa Aminotran_5 PF00266.19 CDJ50129.1 - 1.6e-40 139.2 0.0 4.8e-26 91.6 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V Secretin_N_2 PF07655.13 CDJ50129.1 - 0.00075 20.0 7.7 0.0016 19.0 7.7 1.4 1 0 0 1 1 1 1 Secretin N-terminal domain Cys_Met_Meta_PP PF01053.20 CDJ50129.1 - 0.047 12.2 0.0 0.079 11.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Apt1 PF10351.9 CDJ50129.1 - 0.2 10.5 0.7 0.27 10.1 0.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ50129.1 - 0.78 8.2 2.7 1 7.9 2.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF515 PF04415.12 CDJ50129.1 - 1.5 7.1 8.9 2.7 6.3 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) AF-4 PF05110.13 CDJ50129.1 - 3.1 5.7 19.4 4.2 5.3 19.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pkinase PF00069.25 CDJ50130.1 - 9.1e-24 84.2 0.0 2.9e-17 62.9 0.0 4.4 5 0 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ50130.1 - 3.5e-11 42.9 0.0 3.2e-08 33.2 0.0 3.6 4 0 0 4 4 4 2 Protein tyrosine kinase Spt20 PF12090.8 CDJ50130.1 - 0.0086 15.7 17.5 0.0086 15.7 17.5 7.1 5 2 1 6 6 6 2 Spt20 family DDHD PF02862.17 CDJ50130.1 - 9.5 6.3 44.2 0.24 11.5 8.4 5.1 5 0 0 5 5 5 0 DDHD domain YqjK PF13997.6 CDJ50131.1 - 0.0038 17.4 0.7 0.0038 17.4 0.7 2.5 2 0 0 2 2 2 1 YqjK-like protein DUF1175 PF06672.11 CDJ50131.1 - 0.035 13.8 1.0 0.075 12.7 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) Utp11 PF03998.13 CDJ50132.1 - 3.5e-05 23.9 22.4 0.0075 16.2 5.3 2.1 2 0 0 2 2 2 2 Utp11 protein Trp_oprn_chp PF09534.10 CDJ50133.1 - 0.35 10.7 35.3 0.37 10.6 25.0 2.7 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4746 PF15928.5 CDJ50134.1 - 1.5e-05 24.6 13.6 1.5e-05 24.6 6.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4746) TFIIA PF03153.13 CDJ50134.1 - 0.0058 16.7 55.1 0.019 15.0 41.1 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 CDJ50134.1 - 0.097 12.7 13.7 0.14 12.1 9.7 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DUF2052 PF09747.9 CDJ50134.1 - 0.24 11.5 22.5 1.2 9.2 16.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) 7tm_1 PF00001.21 CDJ50134.1 - 0.53 9.6 2.9 1.2 8.4 2.9 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) LAP1C PF05609.12 CDJ50134.1 - 0.85 8.6 23.5 0.7 8.9 18.1 2.0 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 CDJ50134.1 - 0.92 6.5 19.7 0.31 8.1 13.5 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Auxin_canalis PF05703.11 CDJ50134.1 - 0.98 9.3 32.2 0.022 14.7 13.7 2.1 2 0 0 2 2 2 0 Auxin canalisation Kei1 PF08552.11 CDJ50134.1 - 1 9.2 18.2 2.8 7.8 4.9 2.4 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 PAT1 PF09770.9 CDJ50134.1 - 1.1 7.4 40.6 0.083 11.2 29.7 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 HCO3_cotransp PF00955.21 CDJ50134.1 - 1.5 7.6 4.6 2.7 6.7 4.6 1.4 1 0 0 1 1 1 0 HCO3- transporter family Band_3_cyto PF07565.13 CDJ50134.1 - 1.5 8.5 16.6 2.1 8.1 13.5 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4050 PF13259.6 CDJ50134.1 - 1.5 9.1 17.0 0.75 10.1 10.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) SID-1_RNA_chan PF13965.6 CDJ50134.1 - 1.9 6.8 7.3 3.1 6.1 7.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 CDJ50134.1 - 4.6 6.2 17.7 0.95 8.4 11.8 2.0 2 0 0 2 2 2 0 CLN3 protein Membralin PF09746.9 CDJ50134.1 - 4.9 6.1 12.4 1 8.3 8.5 1.7 2 0 0 2 2 2 0 Tumour-associated protein MDM10 PF12519.8 CDJ50134.1 - 7.7 5.3 16.8 0.65 8.8 11.6 1.7 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 H_PPase PF03030.16 CDJ50136.1 - 1.3e-218 727.8 21.3 1.6e-218 727.6 21.3 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Pex14_N PF04695.13 CDJ50137.1 - 0.34 11.6 26.7 0.39 11.4 26.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM91_C PF14648.6 CDJ50137.1 - 0.81 8.5 12.1 0.87 8.4 12.1 1.0 1 0 0 1 1 1 0 FAM91 C-terminus eIF-3_zeta PF05091.12 CDJ50137.1 - 2 7.3 24.3 2.1 7.3 24.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_U57 PF05582.12 CDJ50137.1 - 2.2 7.4 12.8 2.2 7.5 12.8 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Band_3_cyto PF07565.13 CDJ50137.1 - 2.8 7.7 14.7 2.7 7.7 14.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BAF1_ABF1 PF04684.13 CDJ50137.1 - 3.1 6.8 20.6 3.4 6.6 20.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1764 PF08576.10 CDJ50137.1 - 3.3 8.7 15.8 3.8 8.5 15.8 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) FAM60A PF15396.6 CDJ50137.1 - 3.4 7.6 13.0 3.6 7.5 13.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Coilin_N PF15862.5 CDJ50137.1 - 3.9 7.3 23.6 5.3 6.9 23.6 1.2 1 0 0 1 1 1 0 Coilin N-terminus SpoIIP PF07454.11 CDJ50137.1 - 3.9 6.8 19.7 3.9 6.9 19.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Spt20 PF12090.8 CDJ50137.1 - 4 7.0 44.8 5.1 6.6 44.8 1.3 1 0 0 1 1 1 0 Spt20 family DUF5327 PF17261.2 CDJ50137.1 - 4.1 8.2 26.2 5.2 7.9 26.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Rxt3 PF08642.10 CDJ50137.1 - 4.2 8.2 9.9 4.9 7.9 9.9 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 CDC45 PF02724.14 CDJ50137.1 - 4.7 5.4 16.4 4.8 5.3 16.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Suf PF05843.14 CDJ50137.1 - 4.9 7.0 23.7 5.1 7.0 23.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PPL5 PF18168.1 CDJ50137.1 - 5 6.3 13.2 4.9 6.3 13.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 PAT1 PF09770.9 CDJ50137.1 - 5 5.3 30.9 5.2 5.2 30.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPSF100_C PF13299.6 CDJ50137.1 - 5 7.3 18.0 5.8 7.1 18.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 CDJ50137.1 - 5.2 7.2 17.1 5.4 7.1 17.1 1.1 1 0 0 1 1 1 0 DDHD domain DUF4616 PF15394.6 CDJ50137.1 - 5.5 5.9 16.0 5.9 5.7 16.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) Velvet PF11754.8 CDJ50137.1 - 5.5 6.9 16.9 5.5 6.8 16.9 1.0 1 0 0 1 1 1 0 Velvet factor NARP1 PF12569.8 CDJ50137.1 - 5.6 5.8 21.7 5.9 5.7 21.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Gti1_Pac2 PF09729.9 CDJ50137.1 - 6.4 6.8 13.5 6.3 6.9 13.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Connexin PF00029.19 CDJ50137.1 - 6.6 6.4 14.0 6.5 6.4 14.0 1.1 1 0 0 1 1 1 0 Connexin TALPID3 PF15324.6 CDJ50137.1 - 6.8 4.2 27.4 7.3 4.1 27.4 1.0 1 0 0 1 1 1 0 Hedgehog signalling target RR_TM4-6 PF06459.12 CDJ50137.1 - 7 6.4 22.4 7.6 6.3 22.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 R_equi_Vir PF05526.11 CDJ50137.1 - 7.7 6.3 12.5 9.6 6.0 12.5 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SLC12 PF03522.15 CDJ50137.1 - 7.9 5.4 18.1 8 5.4 18.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ50137.1 - 8.3 5.1 23.7 8.9 5.0 23.7 1.0 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 CDJ50137.1 - 9.4 5.7 14.0 9.2 5.7 14.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 AAA_23 PF13476.6 CDJ50137.1 - 9.5 6.7 20.9 9.3 6.7 20.9 1.1 1 0 0 1 1 1 0 AAA domain DUF913 PF06025.12 CDJ50137.1 - 9.7 5.1 15.1 9.7 5.1 15.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spt20 PF12090.8 CDJ50138.1 - 0.0018 18.0 66.0 0.13 11.9 12.2 3.6 3 0 0 3 3 3 3 Spt20 family DDHD PF02862.17 CDJ50138.1 - 0.19 11.8 0.1 0.19 11.8 0.1 4.2 3 1 0 3 3 3 0 DDHD domain Presenilin PF01080.17 CDJ50138.1 - 0.83 8.3 27.5 0.86 8.3 13.7 2.6 2 0 0 2 2 2 0 Presenilin PAT1 PF09770.9 CDJ50138.1 - 0.89 7.7 42.6 0.89 7.7 7.6 2.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4834 PF16118.5 CDJ50138.1 - 4 8.5 34.7 0.75 10.8 2.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) MDM10 PF12519.8 CDJ50138.1 - 4.6 6.0 14.9 1.5 7.6 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 MRNIP PF15749.5 CDJ50138.1 - 7.3 7.4 33.5 6.9 7.4 3.6 3.6 3 0 0 3 3 3 0 MRN-interacting protein SLC12 PF03522.15 CDJ50138.1 - 9.3 5.1 21.9 7.5 5.5 1.8 2.3 2 0 0 2 2 2 0 Solute carrier family 12 Presenilin PF01080.17 CDJ50140.1 - 0.007 15.2 0.0 0.0092 14.8 0.0 1.3 1 0 0 1 1 1 1 Presenilin GREB1 PF15782.5 CDJ50140.1 - 0.0074 13.5 9.3 0.0097 13.1 9.3 1.1 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer Activator_LAG-3 PF11498.8 CDJ50140.1 - 0.011 14.8 17.4 0.016 14.2 17.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ50140.1 - 0.02 14.5 17.3 0.029 14.0 17.3 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ50140.1 - 0.027 14.5 4.1 0.036 14.0 4.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1635 PF07795.11 CDJ50140.1 - 0.03 14.2 8.7 0.045 13.6 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF2722 PF10846.8 CDJ50140.1 - 0.089 11.7 17.3 0.15 11.0 17.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Plasmodium_Vir PF05795.11 CDJ50140.1 - 0.12 11.8 1.7 0.15 11.4 1.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.9 CDJ50140.1 - 0.14 10.7 5.2 0.3 9.6 5.2 1.6 1 0 0 1 1 1 0 Macoilin family AF-4 PF05110.13 CDJ50140.1 - 0.2 9.7 15.2 0.28 9.2 15.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein EIF4E-T PF10477.9 CDJ50140.1 - 0.33 9.7 9.6 0.43 9.4 9.6 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF1645 PF07816.11 CDJ50140.1 - 0.36 11.4 9.3 0.87 10.1 9.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Lin-8 PF03353.15 CDJ50140.1 - 0.53 9.8 9.4 0.73 9.3 9.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Miga PF10265.9 CDJ50140.1 - 0.72 8.8 6.5 1.1 8.2 6.5 1.2 1 0 0 1 1 1 0 Mitoguardin MAP65_ASE1 PF03999.12 CDJ50140.1 - 0.75 8.4 7.4 1 8.0 7.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SR-25 PF10500.9 CDJ50140.1 - 1 8.9 23.5 1.3 8.6 0.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RAB3GAP2_N PF14655.6 CDJ50140.1 - 1.4 8.1 6.1 2.9 7.0 6.1 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3464 PF11947.8 CDJ50140.1 - 1.6 8.5 7.2 4.7 7.0 7.2 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CPSF100_C PF13299.6 CDJ50140.1 - 1.6 8.9 5.1 0.61 10.3 1.6 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PAT1 PF09770.9 CDJ50140.1 - 2 6.6 12.8 2.7 6.1 12.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.9 CDJ50140.1 - 3.1 6.6 8.7 4 6.2 8.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain UPF0560 PF10577.9 CDJ50140.1 - 3.1 6.2 11.3 4.3 5.7 11.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DivIC PF04977.15 CDJ50140.1 - 9 6.1 12.5 15 5.5 12.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Peptidase_S64 PF08192.11 CDJ50140.1 - 9.4 4.6 9.8 13 4.2 9.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 RskA PF10099.9 CDJ50141.1 - 0.0046 17.3 10.8 0.0067 16.7 10.8 1.4 1 1 0 1 1 1 1 Anti-sigma-K factor rskA Glyco_hydro_9 PF00759.19 CDJ50141.1 - 0.014 14.9 2.6 0.016 14.7 2.6 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 GRP PF07172.11 CDJ50141.1 - 0.018 15.7 0.5 0.034 14.8 0.5 1.4 1 0 0 1 1 1 0 Glycine rich protein family Plasmodium_Vir PF05795.11 CDJ50141.1 - 0.59 9.5 3.0 0.63 9.4 3.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Chorion_2 PF03964.15 CDJ50141.1 - 0.85 10.5 16.7 1.1 10.1 0.6 2.3 2 0 0 2 2 2 0 Chorion family 2 Suf PF05843.14 CDJ50141.1 - 2.2 8.2 7.9 3.3 7.6 7.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ50141.1 - 3.2 7.7 5.0 4 7.4 5.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_60s PF00428.19 CDJ50141.1 - 7.8 7.2 12.8 15 6.3 12.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein SUIM_assoc PF16619.5 CDJ50142.1 - 2.4e-07 30.7 0.0 9.8e-05 22.3 0.0 6.1 3 2 2 5 5 5 3 Unstructured region C-term to UIM in Ataxin3 Metallophos PF00149.28 CDJ50142.1 - 0.0045 17.5 0.0 0.021 15.3 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase RRM_1 PF00076.22 CDJ50143.1 - 3.3e-05 23.6 0.0 5.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 CDJ50143.1 - 0.093 12.7 25.2 0.12 12.3 25.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ50143.1 - 0.26 9.9 34.7 0.3 9.7 34.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Menin PF05053.13 CDJ50143.1 - 0.87 7.9 14.8 1 7.6 14.8 1.1 1 0 0 1 1 1 0 Menin Neur_chan_memb PF02932.16 CDJ50143.1 - 2.1 8.3 6.4 2.6 8.0 6.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ50143.1 - 4.7 5.9 19.1 5.4 5.7 19.1 1.1 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 CDJ50143.1 - 5.7 6.2 25.9 6.7 6.0 25.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_23 PF13476.6 CDJ50144.1 - 4.1 7.8 33.7 9.5 6.7 0.4 3.0 3 0 0 3 3 3 0 AAA domain Presenilin PF01080.17 CDJ50144.1 - 4.9 5.8 51.1 0.079 11.7 24.6 3.6 3 0 0 3 3 3 0 Presenilin Glycolytic PF00274.19 CDJ50145.1 - 2.5e-159 529.6 0.0 2.9e-159 529.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Trypan_PARP PF05887.11 CDJ50146.1 - 1.5 8.8 9.5 2.1 8.3 8.9 1.7 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 CDJ50146.1 - 2.6 7.6 23.6 6.9e+03 -3.6 23.6 2.4 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Spt20 PF12090.8 CDJ50147.1 - 4.8 6.7 22.0 0.27 10.8 14.0 2.2 2 0 0 2 2 2 0 Spt20 family DUF1844 PF08899.11 CDJ50147.1 - 6.7 7.1 6.2 10 6.5 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) VasL PF12486.8 CDJ50149.1 - 0.0037 17.1 0.8 0.014 15.3 0.8 1.9 1 0 0 1 1 1 1 Type VI secretion system, EvfB, or VasL DUF1697 PF08002.11 CDJ50150.1 - 0.12 12.8 0.1 0.3 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Sensor PF13796.6 CDJ50153.1 - 0.023 14.8 3.3 0.097 12.7 0.3 2.3 2 0 0 2 2 2 0 Putative sensor CDC45 PF02724.14 CDJ50153.1 - 0.26 9.5 4.2 0.55 8.5 4.2 1.5 1 0 0 1 1 1 0 CDC45-like protein SPAN-X PF07458.12 CDJ50153.1 - 0.49 10.9 6.3 6 7.4 0.3 3.5 3 0 0 3 3 3 0 Sperm protein associated with nucleus, mapped to X chromosome DNA_pol_phi PF04931.13 CDJ50153.1 - 2.1 6.4 7.7 4.1 5.4 7.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 CDJ50153.1 - 5.6 5.1 11.2 0.83 7.8 7.0 1.7 2 0 0 2 2 2 0 Nop14-like family RRN3 PF05327.11 CDJ50153.1 - 7.7 4.9 6.4 14 4.1 6.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.6 CDJ50153.1 - 9.8 6.6 13.3 2.1 8.8 6.1 3.4 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RskA PF10099.9 CDJ50154.1 - 0.0029 17.9 8.6 0.0029 17.9 8.6 4.0 1 1 3 4 4 4 2 Anti-sigma-K factor rskA GHMP_kinases_N PF00288.26 CDJ50154.1 - 0.94 9.8 11.5 4.5 7.6 3.5 2.4 2 0 0 2 2 2 0 GHMP kinases N terminal domain Caldesmon PF02029.15 CDJ50154.1 - 3 6.5 38.4 4.1 6.0 38.4 1.2 1 0 0 1 1 1 0 Caldesmon BK_channel_a PF03493.18 CDJ50155.1 - 4.2e-13 49.3 0.0 9.1e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 CDJ50155.1 - 8.9e-11 41.6 0.3 2.4e-10 40.3 0.3 1.8 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CDJ50155.1 - 3.6e-06 26.4 6.5 7.2e-06 25.4 6.5 1.4 1 0 0 1 1 1 1 Ion transport protein WBP-1 PF11669.8 CDJ50155.1 - 0.97 10.1 3.4 1.6 9.4 0.4 2.9 2 0 0 2 2 2 0 WW domain-binding protein 1 DFRP_C PF16543.5 CDJ50156.1 - 0.015 15.8 1.4 0.015 15.8 0.8 1.4 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Hydin_ADK PF17213.3 CDJ50156.1 - 2.4 8.4 9.8 2.8 8.2 9.8 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Solute_trans_a PF03619.16 CDJ50157.1 - 3.8e-33 115.1 5.2 3.4e-28 98.9 0.6 2.1 2 0 0 2 2 2 2 Organic solute transporter Ostalpha tRNA-synt_1b PF00579.25 CDJ50158.1 - 1.2e-08 34.6 7.8 1.2e-08 34.6 7.8 5.3 3 2 1 4 4 4 2 tRNA synthetases class I (W and Y) S4 PF01479.25 CDJ50158.1 - 5.5e-05 22.8 0.0 9.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 S4 domain DUF2722 PF10846.8 CDJ50158.1 - 0.0007 18.7 16.5 0.0007 18.7 16.5 10.1 5 3 5 10 10 10 2 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ50158.1 - 0.00098 19.5 1.5 0.00098 19.5 1.5 7.9 2 2 3 6 6 6 3 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ50158.1 - 0.002 18.1 0.4 0.002 18.1 0.4 12.4 7 2 2 9 9 9 3 Unstructured region C-term to UIM in Ataxin3 DUF702 PF05142.12 CDJ50158.1 - 0.0027 18.2 6.9 0.0027 18.2 6.9 9.4 5 3 2 7 7 7 1 Domain of unknown function (DUF702) SR-25 PF10500.9 CDJ50158.1 - 0.0076 15.9 1.4 0.0076 15.9 1.4 7.3 5 3 2 7 7 7 1 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ50159.1 - 0.015 14.3 15.6 0.014 14.3 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ50159.1 - 0.05 13.2 25.2 0.062 12.9 25.2 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ50159.1 - 0.87 9.5 28.3 0.89 9.5 28.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CDJ50159.1 - 1.1 8.2 28.2 1 8.2 28.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CDK2AP PF09806.9 CDJ50159.1 - 1.4 9.0 24.3 1.7 8.7 24.3 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein NST1 PF13945.6 CDJ50159.1 - 1.7 8.7 16.0 2 8.5 16.0 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator FSA_C PF10479.9 CDJ50159.1 - 5.6 5.0 9.1 5.7 4.9 9.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PGA2 PF07543.12 CDJ50159.1 - 6.2 6.8 14.6 9.5 6.2 14.6 1.4 1 1 0 1 1 1 0 Protein trafficking PGA2 Tic110 PF16940.5 CDJ50159.1 - 7.3 5.0 15.8 8.5 4.7 15.8 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter RLL PF10036.9 CDJ50159.1 - 9.4 6.0 18.1 10 5.9 18.1 1.0 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein SUIM_assoc PF16619.5 CDJ50161.1 - 3.5e-09 36.6 0.0 0.00012 22.1 0.0 14.3 9 3 3 12 12 12 3 Unstructured region C-term to UIM in Ataxin3 NAM-associated PF14303.6 CDJ50161.1 - 0.00063 20.5 0.0 0.00063 20.5 0.0 10.1 6 3 1 7 7 7 2 No apical meristem-associated C-terminal domain HSP70 PF00012.20 CDJ50162.1 - 1.9e-201 670.4 0.2 2.1e-201 670.2 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ50162.1 - 7.5e-11 41.4 0.5 5.9e-10 38.5 0.0 2.4 3 1 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.16 CDJ50162.1 - 0.0024 17.7 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain LpxI_N PF17930.1 CDJ50162.1 - 0.04 13.8 0.0 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 LpxI N-terminal domain SR-25 PF10500.9 CDJ50162.1 - 0.39 10.3 7.2 0.81 9.2 7.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HC2 PF07382.11 CDJ50163.1 - 0.019 15.0 15.6 0.029 14.4 15.6 1.3 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Presenilin PF01080.17 CDJ50164.1 - 1.6 7.4 23.8 1.9 7.1 23.8 1.0 1 0 0 1 1 1 0 Presenilin SprA-related PF12118.8 CDJ50164.1 - 7 5.7 35.1 10 5.2 35.1 1.2 1 0 0 1 1 1 0 SprA-related family DUF4064 PF13273.6 CDJ50165.1 - 0.00012 22.3 8.1 0.13 12.5 0.0 5.1 5 0 0 5 5 5 2 Protein of unknown function (DUF4064) DUF2459 PF09601.10 CDJ50165.1 - 0.014 15.2 0.5 0.89 9.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) DUF2681 PF10883.8 CDJ50165.1 - 0.025 15.0 0.7 0.025 15.0 0.7 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2681) Tmemb_9 PF05434.11 CDJ50165.1 - 3.7 7.4 0.0 3.7 7.4 0.0 4.3 6 0 0 6 6 6 0 TMEM9 DUF4131 PF13567.6 CDJ50165.1 - 8.9 5.9 22.3 4.3 7.0 8.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) SR-25 PF10500.9 CDJ50166.1 - 0.00076 19.2 19.7 0.0059 16.2 16.6 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ50166.1 - 0.0054 16.8 19.2 0.0067 16.5 19.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit EIF4E-T PF10477.9 CDJ50166.1 - 0.0074 15.2 6.0 0.0095 14.8 6.0 1.2 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Macoilin PF09726.9 CDJ50166.1 - 0.042 12.4 8.7 0.052 12.1 8.7 1.3 1 0 0 1 1 1 0 Macoilin family DUF1635 PF07795.11 CDJ50166.1 - 0.052 13.4 9.8 0.11 12.3 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) GREB1 PF15782.5 CDJ50166.1 - 0.08 10.1 14.8 0.094 9.8 14.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ50166.1 - 0.082 11.2 10.9 0.097 10.9 10.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2572 PF10833.8 CDJ50166.1 - 0.16 11.7 8.3 0.26 11.0 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Spt20 PF12090.8 CDJ50166.1 - 0.3 10.6 17.8 0.021 14.4 11.7 1.9 2 0 0 2 2 2 0 Spt20 family TMEM151 PF14857.6 CDJ50166.1 - 0.33 9.8 5.7 0.4 9.5 5.7 1.2 1 0 0 1 1 1 0 TMEM151 family NEMP PF10225.9 CDJ50166.1 - 3.4 7.3 7.0 1.3 8.6 3.3 1.9 2 0 0 2 2 2 0 NEMP family IHABP4_N PF16174.5 CDJ50166.1 - 7.8 7.1 13.9 3.7 8.1 9.1 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Activator_LAG-3 PF11498.8 CDJ50168.1 - 6.4e-05 22.1 53.2 6.4e-05 22.1 53.2 9.4 7 2 1 8 8 8 2 Transcriptional activator LAG-3 Kelch_4 PF13418.6 CDJ50171.1 - 1.4e-14 53.9 0.1 8.5e-05 22.5 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ50171.1 - 5.9e-13 48.7 0.1 0.00037 20.7 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ50171.1 - 2.7e-07 30.7 0.0 7.3e-05 22.9 0.0 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 CDJ50171.1 - 2.7e-07 30.4 0.0 8.5e-05 22.4 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 CDJ50171.1 - 1.5e-05 24.7 0.3 0.0011 18.8 0.0 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 CDJ50171.1 - 0.00098 18.7 0.1 0.04 13.5 0.0 2.5 2 0 0 2 2 2 1 Kelch motif RskA PF10099.9 CDJ50171.1 - 0.011 16.0 0.1 0.011 16.0 0.1 3.6 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Miga PF10265.9 CDJ50171.1 - 0.49 9.3 5.5 0.9 8.4 5.5 1.3 1 0 0 1 1 1 0 Mitoguardin PAT1 PF09770.9 CDJ50171.1 - 0.97 7.6 18.1 1.5 7.0 18.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ50171.1 - 7 5.8 14.0 5.4 6.1 7.1 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter DUF1645 PF07816.11 CDJ50172.1 - 0.0013 19.4 0.3 0.0013 19.4 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1645) BPL_N PF09825.9 CDJ50172.1 - 0.44 9.6 6.5 0.039 13.0 0.9 1.8 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal Spt20 PF12090.8 CDJ50172.1 - 1.1 8.8 15.0 0.11 12.1 5.7 2.2 2 0 0 2 2 2 0 Spt20 family GAGA_bind PF06217.12 CDJ50173.1 - 0.011 16.0 16.9 0.013 15.8 16.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SMYLE_N PF18615.1 CDJ50173.1 - 0.023 14.3 19.6 0.031 13.8 19.6 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Presenilin PF01080.17 CDJ50173.1 - 0.024 13.4 31.0 0.029 13.1 31.0 1.1 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 CDJ50173.1 - 0.035 12.9 19.7 0.037 12.8 19.7 1.0 1 0 0 1 1 1 0 Raftlin U1snRNP70_N PF12220.8 CDJ50173.1 - 0.038 14.6 2.3 0.038 14.6 2.3 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SARAF PF06682.12 CDJ50173.1 - 0.089 12.4 23.4 0.11 12.1 23.4 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4045 PF13254.6 CDJ50173.1 - 0.14 11.8 24.6 0.17 11.5 24.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF572 PF04502.13 CDJ50173.1 - 0.23 11.1 23.2 0.27 10.8 23.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3169 PF11368.8 CDJ50173.1 - 0.24 10.9 0.0 0.24 10.9 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Mif2_N PF15624.6 CDJ50173.1 - 0.38 11.5 18.6 0.49 11.1 18.6 1.1 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal ALMT PF11744.8 CDJ50173.1 - 0.51 9.1 18.4 0.61 8.9 18.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Dsh_C PF12316.8 CDJ50173.1 - 0.6 10.5 18.7 0.79 10.1 18.7 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RR_TM4-6 PF06459.12 CDJ50173.1 - 0.83 9.4 27.2 1.3 8.8 27.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 CDJ50173.1 - 1.2 9.3 37.4 1.5 8.9 37.4 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PAT1 PF09770.9 CDJ50173.1 - 1.5 7.0 45.8 1.8 6.7 45.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2052 PF09747.9 CDJ50173.1 - 2.4 8.3 26.7 3.4 7.7 26.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Hid1 PF12722.7 CDJ50173.1 - 2.7 6.0 30.6 3.1 5.8 30.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MMR1 PF08505.10 CDJ50173.1 - 2.8 8.2 33.9 3.7 7.8 33.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Trp_oprn_chp PF09534.10 CDJ50173.1 - 6.5 6.5 10.3 22 4.8 10.3 1.9 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Rgp1 PF08737.10 CDJ50173.1 - 6.9 5.7 23.8 7.6 5.6 23.8 1.0 1 0 0 1 1 1 0 Rgp1 FAM91_C PF14648.6 CDJ50173.1 - 8.2 5.1 17.4 12 4.6 17.4 1.2 1 0 0 1 1 1 0 FAM91 C-terminus APC_basic PF05956.11 CDJ50173.1 - 8.4 5.7 32.8 12 5.3 32.8 1.2 1 0 0 1 1 1 0 APC basic domain PA26 PF04636.13 CDJ50173.1 - 9.8 5.0 22.2 13 4.6 22.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HEAT PF02985.22 CDJ50174.1 - 7.4e-17 60.0 77.3 6.8e-05 22.8 0.3 19.1 19 0 0 19 19 19 7 HEAT repeat Cnd1 PF12717.7 CDJ50174.1 - 2.6e-09 37.3 0.1 0.16 12.0 0.0 5.9 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ50174.1 - 1.2e-06 28.9 18.0 0.0001 22.6 7.8 14.5 10 5 6 16 16 16 6 HEAT repeats HEAT_EZ PF13513.6 CDJ50174.1 - 2.6e-06 27.8 8.3 0.00025 21.5 0.8 27.2 20 6 9 29 29 29 10 HEAT-like repeat Adaptin_N PF01602.20 CDJ50174.1 - 3.9e-06 25.7 6.2 0.14 10.7 0.1 4.8 3 1 2 5 5 5 2 Adaptin N terminal region ParcG PF10274.9 CDJ50174.1 - 0.0017 18.5 5.9 6.5 6.8 0.1 5.7 4 1 0 4 4 4 1 Parkin co-regulated protein CLASP_N PF12348.8 CDJ50174.1 - 0.013 15.1 14.0 0.12 11.9 0.1 6.1 7 1 0 8 8 8 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 CDJ50174.1 - 0.032 14.8 0.0 60 4.3 0.0 4.7 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region Mo25 PF08569.11 CDJ50175.1 - 0.18 11.1 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Mo25-like TFIIA PF03153.13 CDJ50175.1 - 1.7 8.5 5.9 2.1 8.3 5.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RWD PF05773.22 CDJ50176.1 - 5.3e-13 49.3 1.0 5.3e-13 49.3 1.0 1.9 2 0 0 2 2 2 1 RWD domain RskA PF10099.9 CDJ50176.1 - 0.0013 19.1 3.1 0.002 18.5 1.0 2.2 1 1 0 2 2 2 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ50176.1 - 0.0094 16.0 3.2 0.0094 16.0 3.2 3.3 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 DUF3138 PF11336.8 CDJ50176.1 - 1.4 7.5 5.2 2 6.9 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3995 PF13160.6 CDJ50177.1 - 0.017 15.5 10.4 0.017 15.5 10.4 5.9 4 2 2 6 6 6 0 Protein of unknown function (DUF3995) SR-25 PF10500.9 CDJ50178.1 - 0.00062 19.4 12.3 0.00062 19.4 12.3 9.7 7 2 2 9 9 9 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ50178.1 - 0.0053 17.0 17.4 0.0053 17.0 17.4 13.6 13 2 1 14 14 14 1 Domain of unknown function (DUF755) RskA PF10099.9 CDJ50178.1 - 2.3 8.5 0.0 2.3 8.5 0.0 17.4 2 2 6 10 10 10 0 Anti-sigma-K factor rskA LRR_9 PF14580.6 CDJ50179.1 - 9.4e-07 28.5 1.6 1.9e-06 27.5 1.6 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CDJ50179.1 - 0.0086 15.8 4.5 0.023 14.4 4.3 1.7 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 CDJ50179.1 - 0.056 13.9 6.8 0.081 13.4 5.5 1.9 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Peptidase_M16_C PF05193.21 CDJ50179.1 - 0.78 9.7 5.9 0.73 9.8 0.1 2.4 2 0 0 2 2 2 0 Peptidase M16 inactive domain Exo_endo_phos PF03372.23 CDJ50180.1 - 2.2e-07 30.7 0.0 7.9e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spt20 PF12090.8 CDJ50180.1 - 3.9e-05 23.4 6.5 3.9e-05 23.4 6.5 4.3 2 1 1 3 3 3 1 Spt20 family SUIM_assoc PF16619.5 CDJ50181.1 - 0.00056 19.9 0.5 0.0013 18.8 0.5 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 YqfQ PF14181.6 CDJ50181.1 - 0.77 9.9 3.8 1.6 8.9 3.8 1.5 1 0 0 1 1 1 0 YqfQ-like protein Spt20 PF12090.8 CDJ50181.1 - 7.3 6.1 9.1 11 5.6 9.1 1.2 1 0 0 1 1 1 0 Spt20 family CS PF04969.16 CDJ50182.1 - 5.3e-15 56.2 0.6 1e-14 55.2 0.6 1.5 1 0 0 1 1 1 1 CS domain SGS PF05002.15 CDJ50182.1 - 2e-13 50.2 6.9 3.4e-13 49.5 0.1 2.7 3 0 0 3 3 3 1 SGS domain DUF2254 PF10011.9 CDJ50182.1 - 0.12 11.2 0.2 0.26 10.1 0.1 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) DUF4661 PF15576.6 CDJ50182.1 - 0.17 11.8 2.5 0.22 11.4 2.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4661) HSP20 PF00011.21 CDJ50182.1 - 0.43 10.7 5.3 0.18 12.0 0.3 2.1 1 1 1 2 2 2 0 Hsp20/alpha crystallin family Ribosomal_L3 PF00297.22 CDJ50184.1 - 1.7e-157 524.2 1.0 2e-157 523.9 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RskA PF10099.9 CDJ50185.1 - 2.7e-06 27.8 0.5 2.7e-06 27.8 0.5 6.7 3 2 2 7 7 6 2 Anti-sigma-K factor rskA Radical_SAM PF04055.21 CDJ50185.1 - 4.7e-06 27.1 0.0 0.14 12.5 0.0 3.1 3 0 0 3 3 3 2 Radical SAM superfamily HemN_C PF06969.16 CDJ50185.1 - 0.00064 19.7 1.0 0.0029 17.6 0.0 2.7 2 0 0 2 2 2 1 HemN C-terminal domain UCH PF00443.29 CDJ50185.1 - 0.028 13.9 3.8 0.049 13.1 3.8 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase AAA_23 PF13476.6 CDJ50185.1 - 0.11 13.0 15.7 1.3 9.5 0.2 2.4 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.19 CDJ50185.1 - 1.3 6.9 14.5 0.082 10.8 4.5 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ50185.1 - 2.4 8.1 74.4 0.049 13.6 56.9 3.4 1 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit CLN3 PF02487.17 CDJ50185.1 - 3.2 6.7 10.0 18 4.2 0.1 2.5 2 0 0 2 2 2 0 CLN3 protein DUF572 PF04502.13 CDJ50185.1 - 8.7 5.9 19.7 24 4.4 17.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) Spt20 PF12090.8 CDJ50185.1 - 9 5.8 60.0 0.012 15.2 22.5 4.0 4 0 0 4 4 4 0 Spt20 family DUF4770 PF15994.5 CDJ50185.1 - 9.2 6.5 18.8 1.4 9.1 8.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) RRM_1 PF00076.22 CDJ50186.1 - 5e-14 51.9 0.0 1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ50186.1 - 0.0029 17.6 0.0 0.016 15.2 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CDJ50186.1 - 0.034 13.7 0.0 0.99 9.0 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3295 PF11702.8 CDJ50186.1 - 1 8.7 3.3 1.4 8.2 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) RskA PF10099.9 CDJ50187.1 - 0.00026 21.4 40.4 0.88 9.8 1.6 5.3 3 2 0 3 3 3 3 Anti-sigma-K factor rskA Methyltransf_25 PF13649.6 CDJ50187.1 - 0.029 15.1 0.7 0.55 11.0 0.0 3.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ50187.1 - 0.12 13.0 0.0 19 6.0 0.0 3.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ50187.1 - 1.2 9.9 0.0 1.2 9.9 0.0 3.2 4 0 0 4 4 4 0 Methyltransferase domain DUF4148 PF13663.6 CDJ50188.1 - 0.099 12.8 0.2 0.099 12.8 0.2 7.0 6 1 1 7 7 7 0 Domain of unknown function (DUF4148) TRAP_alpha PF03896.16 CDJ50188.1 - 1.3 8.2 20.7 2.9 7.0 3.0 3.8 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit eIF2_C PF09173.11 CDJ50189.1 - 1.1e-24 86.5 0.1 2.5e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 CDJ50189.1 - 9.5e-11 41.9 1.3 3.4e-10 40.1 0.1 2.5 2 1 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 CDJ50189.1 - 7.7e-08 32.1 0.1 1.5e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SUIM_assoc PF16619.5 CDJ50189.1 - 2.5 8.2 15.6 0.078 13.1 4.0 2.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Mpp10 PF04006.12 CDJ50190.1 - 0.15 10.5 19.3 0.17 10.3 19.3 1.1 1 0 0 1 1 1 0 Mpp10 protein GAGA_bind PF06217.12 CDJ50190.1 - 1.2 9.4 14.2 1.5 9.0 14.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Connexin PF00029.19 CDJ50190.1 - 4.1 7.1 7.0 5.8 6.6 7.0 1.4 1 0 0 1 1 1 0 Connexin TFIIA PF03153.13 CDJ50190.1 - 4.3 7.2 24.4 5.4 6.9 24.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ50190.1 - 4.8 5.0 6.5 6.1 4.6 6.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ50191.1 - 0.15 10.8 33.4 0.17 10.7 33.4 1.0 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ50191.1 - 0.21 10.6 29.0 0.22 10.5 29.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SAGA-Tad1 PF12767.7 CDJ50191.1 - 0.95 9.1 28.6 1.1 8.9 28.6 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Hid1 PF12722.7 CDJ50191.1 - 4.8 5.2 27.2 5.4 5.0 27.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.6 CDJ50191.1 - 5.7 6.9 25.8 7.1 6.6 25.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Pex16 PF08610.10 CDJ50191.1 - 6 5.9 14.8 7.9 5.5 14.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF2052 PF09747.9 CDJ50191.1 - 6.1 6.9 30.3 7.2 6.7 30.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PPP4R2 PF09184.11 CDJ50194.1 - 1.7 8.2 31.7 0.14 11.8 23.1 2.2 2 0 0 2 2 2 0 PPP4R2 ASH PF15780.5 CDJ50195.1 - 0.043 14.0 0.0 1.3 9.3 0.0 2.5 2 1 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PhdYeFM_antitox PF02604.19 CDJ50198.1 - 0.014 15.2 0.4 0.023 14.5 0.4 1.3 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system DUF3886 PF13025.6 CDJ50198.1 - 0.015 15.5 2.3 0.023 14.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DUF1249 PF06853.12 CDJ50198.1 - 0.15 12.1 0.5 0.25 11.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1249) DUF572 PF04502.13 CDJ50198.1 - 0.61 9.7 14.1 0.75 9.4 14.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PDCD2_C PF04194.13 CDJ50198.1 - 2.5 8.1 7.1 9.1 6.3 7.1 1.9 1 1 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain PNISR PF15996.5 CDJ50198.1 - 5.4 7.2 11.2 9.4 6.5 11.1 1.4 1 1 0 1 1 1 0 Arginine/serine-rich protein PNISR FXMRP1_C_core PF12235.8 CDJ50198.1 - 5.4 7.7 21.7 0.38 11.4 15.3 2.0 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Plasmodium_Vir PF05795.11 CDJ50199.1 - 0.0048 16.4 5.2 0.0064 16.0 5.2 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein DUF2956 PF11169.8 CDJ50199.1 - 0.26 11.5 24.3 0.57 10.4 4.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) SAPS PF04499.15 CDJ50199.1 - 0.27 10.0 15.3 0.34 9.7 15.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC27 PF09507.10 CDJ50199.1 - 0.72 9.2 27.2 1.1 8.5 27.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Peptidase_S64 PF08192.11 CDJ50199.1 - 0.89 8.0 15.0 1 7.7 15.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF572 PF04502.13 CDJ50199.1 - 1.2 8.7 23.7 1.6 8.3 23.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Sec62 PF03839.16 CDJ50199.1 - 1.2 8.6 18.7 1.7 8.1 4.3 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 Clr2 PF10383.9 CDJ50199.1 - 1.6 9.5 7.3 0.53 11.1 1.5 2.2 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 Rtf2 PF04641.12 CDJ50199.1 - 2 7.7 24.3 0.19 11.1 3.7 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Spt20 PF12090.8 CDJ50199.1 - 7 6.2 56.6 0.079 12.6 27.0 2.4 1 1 1 2 2 2 0 Spt20 family tRNA_synt_1c_R2 PF04557.15 CDJ50199.1 - 9.2 7.3 27.6 1.5 9.8 8.1 3.2 3 0 0 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 U1snRNP70_N PF12220.8 CDJ50199.1 - 9.9 6.9 25.2 7.3 7.3 2.7 3.2 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AF-4 PF05110.13 CDJ50200.1 - 0.024 12.7 14.2 0.022 12.9 14.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GREB1 PF15782.5 CDJ50200.1 - 0.41 7.7 14.4 0.4 7.7 14.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1635 PF07795.11 CDJ50200.1 - 0.72 9.7 10.8 0.85 9.4 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) MPM1 PF17234.2 CDJ50200.1 - 0.8 9.9 8.8 1 9.6 8.8 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 TFIIA PF03153.13 CDJ50200.1 - 0.82 9.6 29.1 1.1 9.1 29.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ50200.1 - 0.88 9.1 14.3 0.89 9.1 14.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ50200.1 - 1.4 8.5 25.2 0.12 12.0 19.6 1.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ50200.1 - 2 7.2 10.6 1.9 7.2 10.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain NST1 PF13945.6 CDJ50200.1 - 2.1 8.4 15.7 2.6 8.1 15.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator UPF0560 PF10577.9 CDJ50200.1 - 2.4 6.6 12.8 2.3 6.6 12.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MMR1 PF08505.10 CDJ50200.1 - 5.4 7.2 16.4 6 7.1 16.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein MAP65_ASE1 PF03999.12 CDJ50200.1 - 6.7 5.3 15.6 7.3 5.2 15.6 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Band_3_cyto PF07565.13 CDJ50200.1 - 7.5 6.3 9.4 7.8 6.2 9.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pap_E4 PF02711.14 CDJ50200.1 - 8 7.5 9.8 13 6.9 9.7 1.4 1 1 0 1 1 1 0 E4 protein NUDE_C PF04880.13 CDJ50200.1 - 8.4 6.8 22.9 10 6.6 22.9 1.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region LYTB PF02401.18 CDJ50202.1 - 1.1e-61 208.5 5.2 1.7e-56 191.4 4.1 2.2 2 0 0 2 2 2 2 LytB protein zf-C3HC4_2 PF13923.6 CDJ50203.1 - 8.9e-09 35.1 10.8 2.4e-08 33.7 10.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ50203.1 - 1.6e-08 34.2 10.1 1.6e-08 34.2 10.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ50203.1 - 2.6e-08 33.6 11.5 7.5e-08 32.1 11.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ50203.1 - 6.8e-08 32.7 10.0 2e-07 31.2 10.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ50203.1 - 6.8e-08 32.4 5.8 6.8e-08 32.4 5.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ50203.1 - 2.7e-06 27.2 11.3 2.7e-06 27.2 11.3 2.5 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDJ50203.1 - 6.5e-06 26.2 7.4 6.5e-06 26.2 7.4 2.3 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDJ50203.1 - 7.9e-06 25.6 9.7 2.1e-05 24.3 9.7 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 SR-25 PF10500.9 CDJ50203.1 - 0.0069 16.0 16.5 0.0069 16.0 16.5 6.2 5 1 1 6 6 6 2 Nuclear RNA-splicing-associated protein zf-rbx1 PF12678.7 CDJ50203.1 - 0.015 15.6 6.7 0.015 15.6 6.7 3.1 3 1 0 3 3 2 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CDJ50203.1 - 0.15 12.0 3.3 0.29 11.0 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CDJ50203.1 - 2.9 7.7 13.0 0.59 10.0 7.8 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CDJ50203.1 - 4.4 7.1 6.9 10 6.0 6.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger DUF3097 PF11296.8 CDJ50204.1 - 0.67 9.1 2.4 1.2 8.4 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) Med15 PF09606.10 CDJ50204.1 - 4.3 5.9 65.1 6.2 5.4 65.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PTPRCAP PF15713.5 CDJ50204.1 - 7.5 6.8 16.9 1.9 8.8 11.2 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF2244 PF10003.9 CDJ50207.1 - 0.0054 16.4 0.0 0.0054 16.4 0.0 3.4 4 0 0 4 4 4 1 Integral membrane protein (DUF2244) RyR PF02026.16 CDJ50207.1 - 0.28 11.4 37.1 0.71 10.1 1.1 7.9 3 2 5 8 8 8 0 RyR domain SpoIISB_antitox PF14185.6 CDJ50207.1 - 4 7.4 28.5 6.9 6.6 0.3 6.7 3 1 2 6 6 6 0 Antitoxin SpoIISB, type II toxin-antitoxin system Pur_DNA_glyco PF02245.16 CDJ50207.1 - 5 6.5 8.9 0.54 9.7 0.6 3.3 2 2 1 4 4 4 0 Methylpurine-DNA glycosylase (MPG) Lipoprotein_10 PF03202.13 CDJ50207.1 - 6.8 7.1 29.2 3.6 8.0 1.2 4.8 3 2 2 5 5 5 0 Putative mycoplasma lipoprotein, C-terminal region RTC PF01137.21 CDJ50209.1 - 1.2e-22 80.3 2.2 1.9e-22 79.5 2.2 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CDJ50209.1 - 1.9e-12 47.6 9.5 1.9e-12 47.6 9.5 2.9 2 1 0 2 2 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain AAA_11 PF13086.6 CDJ50209.1 - 0.0068 16.2 0.2 0.013 15.3 0.2 1.6 1 1 0 1 1 1 1 AAA domain DUF4834 PF16118.5 CDJ50209.1 - 0.045 14.7 0.7 0.045 14.7 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Nckap1 PF09735.9 CDJ50209.1 - 0.061 11.3 0.1 0.1 10.5 0.1 1.2 1 0 0 1 1 1 0 Membrane-associated apoptosis protein XRCC4 PF06632.12 CDJ50209.1 - 0.094 11.5 1.7 0.18 10.7 1.7 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF2722 PF10846.8 CDJ50209.1 - 0.1 11.6 14.6 0.11 11.4 11.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4820 PF16091.5 CDJ50209.1 - 0.13 11.6 1.9 0.33 10.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) FAM176 PF14851.6 CDJ50209.1 - 0.14 11.8 0.5 0.26 10.9 0.5 1.4 1 0 0 1 1 1 0 FAM176 family DUF5327 PF17261.2 CDJ50209.1 - 0.55 11.0 10.4 0.33 11.7 2.8 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5327) AIF_C PF14721.6 CDJ50209.1 - 2.9 8.3 7.2 22 5.4 0.1 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RPA43_OB PF17875.1 CDJ50209.1 - 3.9 8.1 5.3 73 4.0 0.0 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF3391 PF11871.8 CDJ50209.1 - 3.9 8.0 15.1 12 6.5 2.4 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3391) Spt20 PF12090.8 CDJ50209.1 - 4.1 7.0 23.9 3.5 7.2 18.3 2.1 2 0 0 2 2 2 0 Spt20 family MCR_alpha PF02249.17 CDJ50210.1 - 0.33 11.4 2.4 0.54 10.7 2.4 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain WD40 PF00400.32 CDJ50211.1 - 1.2e-10 41.7 0.5 1e-06 29.3 0.1 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ50211.1 - 0.00045 20.5 0.0 1.9 8.8 0.0 3.8 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PMP22_Claudin PF00822.20 CDJ50211.1 - 0.0036 17.2 0.2 0.011 15.7 0.2 1.7 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family CNDH2_N PF06278.11 CDJ50211.1 - 0.026 14.7 0.4 0.026 14.7 0.4 3.3 4 0 0 4 4 4 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal EPL1 PF10513.9 CDJ50211.1 - 0.49 10.8 13.3 3.4 8.0 0.2 3.3 3 0 0 3 3 3 0 Enhancer of polycomb-like RskA PF10099.9 CDJ50211.1 - 0.63 10.3 54.2 0.032 14.5 8.5 4.5 2 1 1 4 4 4 0 Anti-sigma-K factor rskA Abhydrolase_9_N PF15420.6 CDJ50211.1 - 2.2 8.2 18.0 1 9.3 6.5 3.4 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus Renin_r PF07850.14 CDJ50211.1 - 6.8 7.4 11.2 0.16 12.6 1.4 2.8 3 0 0 3 3 3 0 Renin receptor-like protein MCR_alpha PF02249.17 CDJ50211.1 - 7.5 7.0 14.7 2.7 8.5 0.2 3.4 3 0 0 3 3 3 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Chloroplast_duf PF14476.6 CDJ50212.1 - 0.0086 15.1 0.2 0.0092 15.0 0.2 1.0 1 0 0 1 1 1 1 Petal formation-expressed DUF3506 PF12014.8 CDJ50212.1 - 0.067 13.2 0.7 0.077 13.0 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Spt20 PF12090.8 CDJ50212.1 - 0.23 11.1 16.4 0.24 11.0 16.4 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ50212.1 - 4.2 6.1 17.0 4.4 6.0 17.0 1.1 1 0 0 1 1 1 0 Androgen receptor CcmD PF04995.14 CDJ50212.1 - 4.7 7.4 7.5 8.8 6.5 7.5 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TFIIA PF03153.13 CDJ50212.1 - 5.8 6.8 16.6 5.6 6.8 16.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ50212.1 - 7.9 5.3 14.6 9 5.1 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ50213.1 - 0.028 14.1 41.4 0.15 11.7 6.2 2.2 2 0 0 2 2 2 0 Spt20 family Ndc1_Nup PF09531.10 CDJ50213.1 - 3.5 6.2 20.1 4.2 6.0 20.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IPK PF03770.16 CDJ50216.1 - 2.3e-16 60.2 0.0 2.3e-16 60.2 0.0 7.5 6 3 2 8 8 8 1 Inositol polyphosphate kinase UDPGP PF01704.18 CDJ50217.1 - 1.8e-15 56.5 0.0 9.7e-15 54.1 0.0 2.1 2 1 0 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase DUF2722 PF10846.8 CDJ50217.1 - 0.0039 16.2 0.2 0.0045 16.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RPA43_OB PF17875.1 CDJ50217.1 - 0.16 12.6 1.3 4.1 8.0 0.2 2.6 2 1 1 3 3 3 0 RPA43 OB domain in RNA Pol I Spt20 PF12090.8 CDJ50217.1 - 2.4 7.7 11.7 4 7.0 11.7 1.2 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ50217.1 - 7.9 6.7 0.0 7.9 6.7 0.0 3.9 3 2 0 3 3 3 0 Anti-sigma-K factor rskA AP3D1 PF06375.11 CDJ50218.1 - 7.3 6.8 7.2 1.6 9.0 1.3 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 RBFA PF02033.18 CDJ50219.1 - 7.6e-13 48.8 0.0 2e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Ribosome-binding factor A ACT PF01842.25 CDJ50219.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 ACT domain NIF PF03031.18 CDJ50220.1 - 0.018 14.8 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase SR-25 PF10500.9 CDJ50221.1 - 0.001 18.7 4.2 0.001 18.7 4.2 3.5 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ50221.1 - 0.0013 17.8 0.7 0.0013 17.8 0.7 4.2 3 2 1 4 4 4 1 Protein of unknown function (DUF2722) SprA-related PF12118.8 CDJ50221.1 - 0.0014 17.8 3.4 0.0014 17.8 3.4 3.7 3 1 1 4 4 4 1 SprA-related family SUIM_assoc PF16619.5 CDJ50221.1 - 0.02 15.0 10.1 0.02 15.0 10.1 7.2 6 1 1 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 DUF1645 PF07816.11 CDJ50221.1 - 0.87 10.1 21.1 0.16 12.5 8.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1645) 2-Hacid_dh_C PF02826.19 CDJ50222.1 - 2e-10 40.3 0.0 2e-10 40.3 0.0 2.8 4 0 0 4 4 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2722 PF10846.8 CDJ50222.1 - 0.00012 21.2 69.0 0.019 13.9 14.5 4.2 4 0 0 4 4 4 3 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ50222.1 - 0.00016 20.5 13.2 0.00016 20.5 13.2 3.7 3 1 0 3 3 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ50222.1 - 0.0027 17.3 16.9 0.0027 17.3 16.9 4.2 4 0 0 4 4 4 3 Spt20 family DDHD PF02862.17 CDJ50222.1 - 0.015 15.4 0.6 0.015 15.4 0.6 4.2 2 1 0 2 2 1 0 DDHD domain EPL1 PF10513.9 CDJ50222.1 - 0.073 13.5 30.6 0.89 9.9 4.3 4.2 4 0 0 4 4 4 0 Enhancer of polycomb-like Presenilin PF01080.17 CDJ50222.1 - 0.1 11.3 28.8 0.21 10.3 1.9 3.1 3 0 0 3 3 3 0 Presenilin Nup35_RRM_2 PF14605.6 CDJ50222.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Rxt3 PF08642.10 CDJ50222.1 - 1.9 9.2 20.1 2.3 9.0 0.4 4.5 4 0 0 4 4 4 0 Histone deacetylation protein Rxt3 Neur_chan_memb PF02932.16 CDJ50222.1 - 2.5 8.1 24.6 1.7 8.6 1.0 3.3 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 CDJ50222.1 - 5.8 6.3 31.2 1.7 8.0 0.8 4.1 4 0 0 4 4 4 0 Stage II sporulation protein P (SpoIIP) DUF4834 PF16118.5 CDJ50222.1 - 9.8 7.2 46.1 2.9 8.9 4.3 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Amino_oxidase PF01593.24 CDJ50223.1 - 1.1e-10 41.5 0.0 1.1e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ50223.1 - 0.003 17.8 0.0 0.015 15.5 0.1 4.4 5 0 0 5 5 5 2 NAD(P)-binding Rossmann-like domain Med8 PF10232.9 CDJ50223.1 - 0.097 12.3 0.1 0.097 12.3 0.1 3.3 3 1 0 3 3 3 0 Mediator of RNA polymerase II transcription complex subunit 8 V_ATPase_I PF01496.19 CDJ50223.1 - 0.13 10.1 0.2 0.23 9.4 0.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Suf PF05843.14 CDJ50223.1 - 0.39 10.7 5.4 0.72 9.8 2.1 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Sin_N PF04801.13 CDJ50223.1 - 0.92 8.7 11.7 0.027 13.7 4.8 1.8 2 0 0 2 2 2 0 Sin-like protein conserved region Peroxin-13_N PF04088.13 CDJ50223.1 - 2.1 8.6 7.3 3.7 7.8 0.1 2.9 3 0 0 3 3 3 0 Peroxin 13, N-terminal region IPK PF03770.16 CDJ50225.1 - 6.3e-12 45.8 0.0 1.4e-10 41.4 0.0 2.9 3 1 0 3 3 3 1 Inositol polyphosphate kinase DUF1485 PF07364.12 CDJ50225.1 - 0.018 14.3 4.9 0.028 13.7 4.9 1.2 1 0 0 1 1 1 0 Metallopeptidase family M81 OATP PF03137.20 CDJ50225.1 - 0.34 9.1 0.6 0.53 8.5 0.6 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Spt20 PF12090.8 CDJ50226.1 - 0.0039 16.9 31.8 0.0039 16.8 31.8 1.1 1 0 0 1 1 1 1 Spt20 family DUF5308 PF17233.2 CDJ50226.1 - 0.007 16.6 11.7 0.0085 16.3 11.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5308) Coilin_N PF15862.5 CDJ50226.1 - 0.012 15.4 12.8 0.014 15.2 12.8 1.1 1 0 0 1 1 1 0 Coilin N-terminus G0-G1_switch_2 PF15103.6 CDJ50226.1 - 0.014 15.8 6.9 0.018 15.5 6.9 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 Thg1C PF14413.6 CDJ50226.1 - 0.017 15.3 6.5 0.017 15.2 6.5 1.1 1 0 0 1 1 1 0 Thg1 C terminal domain DUF4834 PF16118.5 CDJ50226.1 - 0.023 15.6 10.2 0.03 15.3 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pex14_N PF04695.13 CDJ50226.1 - 0.024 15.3 18.2 0.025 15.2 18.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 CDJ50226.1 - 0.029 14.4 15.6 0.032 14.3 15.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3499 PF12005.8 CDJ50226.1 - 0.033 14.8 4.9 0.038 14.6 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) eIF-3_zeta PF05091.12 CDJ50226.1 - 0.034 13.2 12.8 0.033 13.2 12.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MecA PF05389.12 CDJ50226.1 - 0.044 13.4 8.7 0.045 13.4 8.7 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) EIIBC-GUT_N PF03612.14 CDJ50226.1 - 0.051 13.3 9.4 0.058 13.1 9.4 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RR_TM4-6 PF06459.12 CDJ50226.1 - 0.051 13.4 9.7 0.053 13.4 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Di19_C PF14571.6 CDJ50226.1 - 0.061 13.8 8.8 0.074 13.6 8.8 1.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal DUF3408 PF11888.8 CDJ50226.1 - 0.074 13.2 10.3 0.082 13.0 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) R_equi_Vir PF05526.11 CDJ50226.1 - 0.076 12.9 5.9 0.082 12.8 5.9 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF4820 PF16091.5 CDJ50226.1 - 0.076 12.4 6.5 0.092 12.1 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Suf PF05843.14 CDJ50226.1 - 0.09 12.8 16.5 0.088 12.8 16.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SpoIIP PF07454.11 CDJ50226.1 - 0.11 11.9 12.4 0.12 11.8 12.4 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CDJ50226.1 - 0.13 11.0 12.2 0.14 10.9 12.2 1.0 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 CDJ50226.1 - 0.17 11.7 6.7 0.18 11.5 6.7 1.1 1 0 0 1 1 1 0 Connexin CPSF100_C PF13299.6 CDJ50226.1 - 0.18 12.0 9.5 0.21 11.8 9.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AIF_C PF14721.6 CDJ50226.1 - 0.19 12.1 10.1 0.21 11.9 10.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2126 PF09899.9 CDJ50226.1 - 0.2 9.7 7.2 0.22 9.6 7.2 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) EOS1 PF12326.8 CDJ50226.1 - 0.21 11.5 6.9 0.22 11.4 6.9 1.1 1 0 0 1 1 1 0 N-glycosylation protein RICTOR_N PF14664.6 CDJ50226.1 - 0.22 10.5 3.8 0.21 10.5 3.8 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Baculo_PP31 PF05311.11 CDJ50226.1 - 0.22 11.0 9.6 0.21 11.0 9.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF2828 PF11443.8 CDJ50226.1 - 0.23 9.5 10.4 0.26 9.3 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SprA-related PF12118.8 CDJ50226.1 - 0.25 10.5 25.0 0.29 10.2 25.0 1.1 1 0 0 1 1 1 0 SprA-related family EPL1 PF10513.9 CDJ50226.1 - 0.29 11.5 11.6 0.33 11.3 11.6 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Folate_carrier PF01770.18 CDJ50226.1 - 0.3 9.8 5.1 0.29 9.8 5.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier MMU163 PF17119.5 CDJ50226.1 - 0.3 10.2 4.7 0.29 10.3 4.7 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis FAM60A PF15396.6 CDJ50226.1 - 0.36 10.8 8.5 0.34 10.9 8.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Pex26 PF07163.12 CDJ50226.1 - 0.46 9.8 11.2 0.41 9.9 11.2 1.1 1 0 0 1 1 1 0 Pex26 protein CCDC53 PF10152.9 CDJ50226.1 - 0.56 10.6 12.0 0.6 10.5 12.0 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Band_3_cyto PF07565.13 CDJ50226.1 - 0.56 10.0 9.0 0.55 10.0 9.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4746 PF15928.5 CDJ50226.1 - 0.69 9.3 7.5 0.73 9.2 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1980 PF09323.10 CDJ50226.1 - 0.7 9.8 7.2 0.77 9.7 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DDHD PF02862.17 CDJ50226.1 - 0.73 10.0 11.3 0.79 9.8 11.3 1.1 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.9 CDJ50226.1 - 0.8 7.9 19.3 0.78 7.9 19.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CobT PF06213.12 CDJ50226.1 - 0.82 9.0 20.7 0.98 8.7 20.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ureide_permease PF07168.11 CDJ50226.1 - 0.84 8.3 4.2 0.87 8.3 4.2 1.1 1 0 0 1 1 1 0 Ureide permease Sec62 PF03839.16 CDJ50226.1 - 0.86 9.1 6.5 0.84 9.1 6.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Med15 PF09606.10 CDJ50226.1 - 0.95 8.1 28.6 0.95 8.1 28.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CSG2 PF16965.5 CDJ50226.1 - 1 8.3 6.2 0.99 8.3 6.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator V_ATPase_I PF01496.19 CDJ50226.1 - 1 7.2 13.8 1 7.2 13.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF702 PF05142.12 CDJ50226.1 - 1.1 9.8 13.0 1.3 9.5 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) CLN3 PF02487.17 CDJ50226.1 - 1.1 8.2 7.9 1.1 8.2 7.9 1.1 1 0 0 1 1 1 0 CLN3 protein HA2 PF04408.23 CDJ50226.1 - 1.2 9.5 12.6 2.3 8.6 12.6 1.5 1 1 0 1 1 1 0 Helicase associated domain (HA2) DUF4407 PF14362.6 CDJ50226.1 - 1.2 8.4 14.3 1.3 8.3 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4175 PF13779.6 CDJ50226.1 - 1.3 6.9 27.2 1.2 7.0 27.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ctr PF04145.15 CDJ50226.1 - 1.3 9.6 5.6 1.4 9.5 5.6 1.1 1 0 0 1 1 1 0 Ctr copper transporter family TFIIA PF03153.13 CDJ50226.1 - 1.3 8.9 34.7 1.3 9.0 34.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.15 CDJ50226.1 - 1.7 7.5 6.4 1.7 7.5 6.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.16 CDJ50226.1 - 1.9 8.5 9.3 1.9 8.5 9.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CDJ50226.1 - 1.9 7.6 6.8 2 7.6 6.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Orf78 PF06024.12 CDJ50226.1 - 1.9 8.8 7.6 2.4 8.5 7.6 1.3 1 0 0 1 1 1 0 Orf78 (ac78) PigN PF04987.14 CDJ50226.1 - 2.1 7.1 4.4 1.8 7.4 4.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Tim54 PF11711.8 CDJ50226.1 - 2.1 7.0 12.1 2.4 6.8 12.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CTU2 PF10288.9 CDJ50226.1 - 2.2 8.6 13.7 2.7 8.3 13.7 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Androgen_recep PF02166.16 CDJ50226.1 - 2.8 6.7 35.0 3.7 6.3 35.0 1.1 1 0 0 1 1 1 0 Androgen receptor DUF1682 PF07946.14 CDJ50226.1 - 2.8 7.1 10.9 3.2 6.9 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF2722 PF10846.8 CDJ50226.1 - 3 6.7 33.1 3.6 6.4 33.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Plasmodium_Vir PF05795.11 CDJ50226.1 - 3.1 7.1 7.8 3.5 7.0 7.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.7 CDJ50226.1 - 3.6 5.6 12.6 3.7 5.5 12.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 CDJ50226.1 - 3.7 6.3 8.2 3.4 6.4 8.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PIP5K PF01504.18 CDJ50226.1 - 6 6.0 11.5 6.9 5.8 11.5 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase UPF0560 PF10577.9 CDJ50226.1 - 6.6 5.1 21.4 7.2 5.0 21.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Kei1 PF08552.11 CDJ50226.1 - 7.3 6.4 11.3 8.1 6.3 11.3 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ephrin_rec_like PF07699.13 CDJ50227.1 - 0.026 14.3 25.1 0.36 10.6 3.8 4.0 1 1 3 4 4 4 0 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 CDJ50229.1 - 1.8e-05 24.4 21.5 8.5e-05 22.2 4.0 35.6 26 10 12 38 38 38 19 Putative ephrin-receptor like Peptidase_M13 PF01431.21 CDJ50229.1 - 0.95 9.0 4.2 0.56 9.8 0.3 2.4 2 0 0 2 2 2 0 Peptidase family M13 DUF2299 PF10061.9 CDJ50229.1 - 2.9 7.6 4.7 24 4.7 1.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2299) PAN_4 PF14295.6 CDJ50230.1 - 2.8e-07 30.3 0.2 4.9e-07 29.6 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 CDJ50230.1 - 1.8e-05 24.6 0.3 3.3e-05 23.8 0.3 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 CDJ50230.1 - 0.0047 17.0 0.4 0.0086 16.2 0.4 1.4 1 0 0 1 1 1 1 PAN-like domain NAM-associated PF14303.6 CDJ50231.1 - 0.0086 16.8 0.0 0.0086 16.8 0.0 11.4 12 2 2 14 14 14 1 No apical meristem-associated C-terminal domain FAM76 PF16046.5 CDJ50231.1 - 0.018 14.4 0.2 0.018 14.4 0.2 9.8 8 2 1 9 9 9 0 FAM76 protein TFIIA PF03153.13 CDJ50232.1 - 0.0017 18.4 21.2 0.0017 18.4 21.2 13.5 5 3 5 11 11 11 2 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 CDJ50232.1 - 9.4 4.5 5.2 12 4.2 0.4 2.6 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 VPS13_C PF16909.5 CDJ50233.1 - 5.8e-06 26.2 1.0 2.2e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal DUF1645 PF07816.11 CDJ50233.1 - 0.016 15.8 0.5 0.016 15.8 0.5 12.3 7 5 2 10 10 10 0 Protein of unknown function (DUF1645) AAA PF00004.29 CDJ50234.1 - 1e-09 38.9 0.0 4.5e-09 36.8 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 CDJ50234.1 - 3.2e-05 24.2 0.1 3.2e-05 24.2 0.1 2.8 3 0 0 3 3 2 1 AAA C-terminal domain Rad17 PF03215.15 CDJ50234.1 - 9e-05 22.5 0.1 0.0011 18.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 CDJ50234.1 - 0.0003 20.6 0.0 0.0007 19.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 CDJ50234.1 - 0.0012 18.2 0.0 0.0034 16.7 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 CDJ50234.1 - 0.0038 17.6 0.1 0.0038 17.6 0.1 6.0 4 4 0 4 4 1 1 AAA ATPase domain MAGE_N PF12440.8 CDJ50234.1 - 0.015 16.0 14.3 0.015 16.0 14.3 9.5 6 3 1 8 8 5 0 Melanoma associated antigen family N terminal TsaE PF02367.17 CDJ50234.1 - 0.069 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CDJ50234.1 - 0.093 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ50234.1 - 0.19 12.0 4.3 0.4 11.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CDJ50234.1 - 0.24 11.5 0.0 0.24 11.5 0.0 3.6 4 1 0 4 4 3 0 AAA domain GEMIN8 PF15348.6 CDJ50236.1 - 0.0074 16.6 3.5 0.0074 16.6 3.5 4.6 4 2 0 4 4 4 1 Gemini of Cajal bodies-associated protein 8 DUF533 PF04391.12 CDJ50236.1 - 0.011 15.3 0.4 0.011 15.3 0.4 7.2 4 3 2 6 6 6 0 Protein of unknown function (DUF533) SPX PF03105.19 CDJ50237.1 - 0.0015 18.6 2.9 0.0015 18.6 2.9 1.2 1 0 0 1 1 1 1 SPX domain DUF4614 PF15391.6 CDJ50237.1 - 0.013 15.5 7.3 0.013 15.5 7.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) Smg8_Smg9 PF10220.9 CDJ50237.1 - 0.12 10.6 1.2 0.15 10.3 1.2 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Apt1 PF10351.9 CDJ50237.1 - 0.24 10.2 6.7 0.28 10.0 6.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ50237.1 - 0.48 8.9 12.8 0.96 7.9 12.8 1.6 1 0 0 1 1 1 0 Macoilin family Tom37_C PF11801.8 CDJ50238.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Apt1 PF10351.9 CDJ50238.1 - 3.1 6.5 6.9 3.9 6.2 6.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Acatn PF13000.7 CDJ50239.1 - 3.2e-05 22.7 0.0 3.6e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 OATP PF03137.20 CDJ50239.1 - 0.00015 20.3 0.0 0.00016 20.1 0.0 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Spt20 PF12090.8 CDJ50239.1 - 0.00017 21.3 10.4 0.00019 21.2 10.4 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ50239.1 - 0.00039 19.5 7.7 0.00039 19.5 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ50239.1 - 0.00042 21.2 1.4 0.00042 21.2 1.4 1.5 2 0 0 2 2 1 1 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ50239.1 - 0.0022 17.8 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 Connexin FAM209 PF15206.6 CDJ50239.1 - 0.0086 15.9 0.2 0.013 15.3 0.2 1.2 1 0 0 1 1 1 1 FAM209 family Nucleoside_tran PF01733.18 CDJ50239.1 - 0.0094 15.4 0.0 0.011 15.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside transporter Conotoxin PF02950.17 CDJ50239.1 - 0.0095 16.9 0.2 0.019 16.0 0.2 1.5 1 0 0 1 1 1 1 Conotoxin Anoctamin PF04547.12 CDJ50239.1 - 0.017 14.0 0.7 0.02 13.7 0.7 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Dpy19 PF10034.9 CDJ50239.1 - 0.02 13.1 0.1 0.022 13.0 0.1 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation RskA PF10099.9 CDJ50239.1 - 0.021 15.1 0.2 0.024 14.9 0.2 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA EphA2_TM PF14575.6 CDJ50239.1 - 0.022 15.6 0.0 0.022 15.6 0.0 1.8 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM144 PF07857.12 CDJ50239.1 - 0.026 13.5 0.0 0.029 13.3 0.0 1.0 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters TssO PF17561.2 CDJ50239.1 - 0.029 14.5 0.8 0.029 14.5 0.8 1.8 2 0 0 2 2 1 0 Type VI secretion system, TssO G0-G1_switch_2 PF15103.6 CDJ50239.1 - 0.031 14.7 0.5 0.04 14.3 0.5 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF4199 PF13858.6 CDJ50239.1 - 0.035 14.5 2.2 0.055 13.9 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4407 PF14362.6 CDJ50239.1 - 0.037 13.4 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ni_hydr_CYTB PF01292.20 CDJ50239.1 - 0.063 12.9 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 FAM70 PF14967.6 CDJ50239.1 - 0.076 12.5 0.1 0.091 12.2 0.1 1.3 1 1 0 1 1 1 0 FAM70 protein Scs3p PF10261.9 CDJ50239.1 - 0.085 12.3 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Med3 PF11593.8 CDJ50239.1 - 0.099 11.8 11.3 0.12 11.6 11.3 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ctr PF04145.15 CDJ50239.1 - 0.12 13.0 0.0 0.15 12.7 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family RNA_pol_Rbc25 PF08292.12 CDJ50239.1 - 0.15 12.3 2.7 0.19 12.0 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Presenilin PF01080.17 CDJ50239.1 - 0.16 10.7 2.3 0.24 10.1 2.3 1.4 1 0 0 1 1 1 0 Presenilin ABC2_membrane_2 PF12679.7 CDJ50239.1 - 0.22 10.7 2.5 0.33 10.2 2.5 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein TFIIA PF03153.13 CDJ50239.1 - 0.32 11.0 13.6 0.36 10.8 13.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CDJ50239.1 - 0.6 9.0 17.1 0.65 8.9 17.1 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4175 PF13779.6 CDJ50239.1 - 0.84 7.5 14.4 0.92 7.3 14.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TMEM208_SND2 PF05620.11 CDJ50239.1 - 3.5 7.4 8.3 0.24 11.2 3.4 1.5 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 HC2 PF07382.11 CDJ50240.1 - 3.7e-08 33.7 8.4 5.2e-08 33.2 8.4 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 TFIIA PF03153.13 CDJ50240.1 - 0.0039 17.3 43.8 0.0046 17.0 43.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GETHR PF05671.11 CDJ50240.1 - 0.091 12.1 13.1 7.1 6.1 0.8 4.5 3 1 0 3 3 3 0 GETHR pentapeptide repeat (5 copies) eIF-3_zeta PF05091.12 CDJ50240.1 - 0.17 10.8 27.0 0.2 10.6 27.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.14 CDJ50240.1 - 0.27 9.5 25.8 0.29 9.4 25.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SCAI PF12070.8 CDJ50240.1 - 0.33 9.7 21.9 0.4 9.5 21.9 1.1 1 0 0 1 1 1 0 Protein SCAI Neur_chan_memb PF02932.16 CDJ50240.1 - 0.39 10.7 19.8 0.47 10.5 19.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PepSY_TM PF03929.16 CDJ50240.1 - 1 9.0 8.8 1.4 8.6 8.8 1.4 1 0 0 1 1 1 0 PepSY-associated TM region Cellulose_synt PF03552.14 CDJ50240.1 - 1.9 6.9 14.1 2.4 6.5 14.1 1.3 1 0 0 1 1 1 0 Cellulose synthase PAT1 PF09770.9 CDJ50240.1 - 2.5 6.3 37.3 2.9 6.1 37.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4638 PF15472.6 CDJ50240.1 - 4.3 7.0 30.6 5.6 6.6 30.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) GREB1 PF15782.5 CDJ50240.1 - 7.7 3.5 22.3 8.1 3.4 22.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ABC2_membrane_2 PF12679.7 CDJ50240.1 - 7.9 5.7 4.7 9.4 5.4 4.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein SLC12 PF03522.15 CDJ50240.1 - 8.5 5.3 32.6 11 4.9 32.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF4175 PF13779.6 CDJ50240.1 - 8.9 4.1 44.7 10 3.9 44.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Acatn PF13000.7 CDJ50241.1 - 9.6e-11 40.9 0.3 1.7e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Spt20 PF12090.8 CDJ50241.1 - 0.0015 18.2 51.6 0.054 13.1 17.8 2.1 2 0 0 2 2 2 2 Spt20 family SARAF PF06682.12 CDJ50241.1 - 0.0086 15.8 13.9 0.011 15.5 13.9 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CCSAP PF15748.5 CDJ50241.1 - 0.036 14.2 26.1 0.045 13.9 26.1 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Rgp1 PF08737.10 CDJ50241.1 - 0.049 12.8 12.3 0.054 12.7 12.3 1.0 1 0 0 1 1 1 0 Rgp1 DUF572 PF04502.13 CDJ50241.1 - 0.13 11.8 15.4 0.17 11.5 15.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOG2 PF10428.9 CDJ50241.1 - 0.23 10.6 20.7 0.3 10.2 20.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SLC12 PF03522.15 CDJ50241.1 - 0.3 10.0 18.5 0.42 9.6 18.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 CDJ50241.1 - 0.41 9.5 13.8 0.49 9.3 13.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Coilin_N PF15862.5 CDJ50241.1 - 0.43 10.4 22.1 0.9 9.3 6.5 2.3 2 0 0 2 2 2 0 Coilin N-terminus Lin-8 PF03353.15 CDJ50241.1 - 0.47 10.0 22.7 0.58 9.7 22.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF92 PF01940.16 CDJ50241.1 - 0.53 9.7 4.8 0.84 9.0 4.8 1.3 1 1 0 1 1 1 0 Integral membrane protein DUF92 ALMT PF11744.8 CDJ50241.1 - 0.65 8.8 14.8 0.84 8.4 14.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Striatin PF08232.12 CDJ50241.1 - 1.3 9.6 23.9 1.2 9.7 11.8 2.1 2 0 0 2 2 2 0 Striatin family AAA_23 PF13476.6 CDJ50241.1 - 1.5 9.2 17.9 2.2 8.7 17.9 1.2 1 0 0 1 1 1 0 AAA domain SpoIIP PF07454.11 CDJ50241.1 - 1.6 8.1 18.5 1.7 8.0 2.4 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Apc15p PF05841.11 CDJ50241.1 - 1.7 9.5 28.9 0.54 11.1 12.7 2.2 2 0 0 2 2 2 0 Apc15p protein SWI-SNF_Ssr4 PF08549.10 CDJ50241.1 - 3.5 6.2 26.1 4.4 5.8 26.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) CSG2 PF16965.5 CDJ50241.1 - 4.6 6.1 10.5 6.9 5.5 10.5 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator PRC2_HTH_1 PF18118.1 CDJ50241.1 - 5.1 7.9 14.7 3.2 8.6 4.8 2.2 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Orf78 PF06024.12 CDJ50241.1 - 5.8 7.3 13.0 2.1 8.7 0.9 2.3 2 0 0 2 2 2 0 Orf78 (ac78) Peptidase_S49_N PF08496.10 CDJ50241.1 - 6.7 6.8 18.6 8 6.5 2.3 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Hid1 PF12722.7 CDJ50241.1 - 8.7 4.3 20.4 10 4.1 20.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Thg1C PF14413.6 CDJ50241.1 - 9.4 6.4 16.1 4.2 7.5 2.2 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain CDC50 PF03381.15 CDJ50242.1 - 1.8e-13 50.7 1.1 2e-10 40.7 0.0 3.0 3 0 0 3 3 3 2 LEM3 (ligand-effect modulator 3) family / CDC50 family SR-25 PF10500.9 CDJ50242.1 - 8.5e-05 22.3 44.6 0.00011 21.9 15.8 3.3 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein SseC PF04888.12 CDJ50242.1 - 0.0014 18.3 10.6 0.0014 18.3 10.6 4.2 3 1 0 3 3 3 1 Secretion system effector C (SseC) like family RskA PF10099.9 CDJ50242.1 - 0.0086 16.4 0.0 0.0086 16.4 0.0 4.5 2 2 2 4 4 4 1 Anti-sigma-K factor rskA Otopetrin PF03189.13 CDJ50242.1 - 0.12 11.2 0.0 0.27 10.0 0.0 1.7 1 1 0 1 1 1 0 Otopetrin TPP_enzyme_C PF02775.21 CDJ50242.1 - 0.71 9.7 0.0 0.71 9.7 0.0 4.1 5 2 1 6 6 6 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Suf PF05843.14 CDJ50242.1 - 3.6 7.5 36.7 0.089 12.8 14.7 2.4 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) SOBP PF15279.6 CDJ50242.1 - 7.5 7.1 30.1 1.7 9.2 14.4 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein Mito_carr PF00153.27 CDJ50243.1 - 5e-19 68.0 0.1 5e-19 68.0 0.1 6.3 4 0 0 4 4 4 1 Mitochondrial carrier protein AP2 PF00847.20 CDJ50243.1 - 5.7e-05 23.3 0.5 5.7e-05 23.3 0.5 6.3 5 0 0 5 5 5 2 AP2 domain Spt20 PF12090.8 CDJ50243.1 - 0.00044 19.9 27.5 0.00086 19.0 11.1 18.6 8 5 3 12 12 12 2 Spt20 family TFIIA PF03153.13 CDJ50243.1 - 0.00084 19.4 13.6 0.00084 19.4 13.6 12.3 3 2 7 10 10 10 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ50243.1 - 0.0039 16.9 19.2 0.0039 16.9 19.2 18.1 12 5 5 19 19 19 4 Nuclear RNA-splicing-associated protein AAA_lid_10 PF17872.1 CDJ50243.1 - 0.012 15.7 0.0 0.093 12.9 0.0 2.7 1 0 0 1 1 1 0 AAA lid domain DUF2722 PF10846.8 CDJ50243.1 - 0.022 13.8 0.1 0.022 13.8 0.1 20.1 11 6 4 15 15 15 0 Protein of unknown function (DUF2722) zf-C3HC4_3 PF13920.6 CDJ50244.1 - 0.0043 16.9 0.7 0.0066 16.3 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Activator_LAG-3 PF11498.8 CDJ50244.1 - 0.023 13.7 12.3 0.038 13.0 12.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF1635 PF07795.11 CDJ50244.1 - 0.69 9.7 13.5 0.64 9.8 6.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) TFIIA PF03153.13 CDJ50244.1 - 7.1 6.5 12.9 0.43 10.5 7.7 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Phage_TAC_7 PF10109.9 CDJ50245.1 - 0.0033 17.5 0.5 0.0081 16.3 0.5 1.6 1 0 0 1 1 1 1 Phage tail assembly chaperone proteins, E, or 41 or 14 DUF2312 PF10073.9 CDJ50245.1 - 0.18 11.5 0.0 0.54 9.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF4175 PF13779.6 CDJ50246.1 - 0.0058 14.6 14.0 0.0059 14.6 14.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) SR-25 PF10500.9 CDJ50246.1 - 0.035 13.7 23.3 0.06 13.0 23.3 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ50246.1 - 0.048 13.7 27.4 0.058 13.4 27.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ50246.1 - 0.05 13.2 17.5 0.056 13.0 17.5 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ50246.1 - 0.053 12.1 11.6 0.056 12.0 11.6 1.0 1 0 0 1 1 1 0 Macoilin family DUF1645 PF07816.11 CDJ50246.1 - 0.062 13.9 10.5 0.078 13.5 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) ATP-synt_B PF00430.18 CDJ50246.1 - 0.12 12.5 0.7 0.12 12.5 0.7 2.5 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) DDE_Tnp_1_2 PF13586.6 CDJ50246.1 - 0.16 12.3 1.3 0.3 11.5 1.3 1.4 1 0 0 1 1 1 0 Transposase DDE domain Apt1 PF10351.9 CDJ50246.1 - 0.28 10.0 11.8 0.32 9.8 11.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Allexi_40kDa PF05549.11 CDJ50246.1 - 0.57 9.7 6.5 0.64 9.5 6.5 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Ecl1 PF12855.7 CDJ50246.1 - 0.76 10.9 17.6 0.87 10.7 17.6 1.1 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins MPM1 PF17234.2 CDJ50246.1 - 0.82 9.9 12.5 1.3 9.3 12.5 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Presenilin PF01080.17 CDJ50246.1 - 3.2 6.4 14.6 3.6 6.2 14.6 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ50246.1 - 3.3 7.7 6.2 4 7.4 6.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PepSY_TM PF03929.16 CDJ50246.1 - 3.9 7.1 6.9 4.9 6.7 6.9 1.3 1 0 0 1 1 1 0 PepSY-associated TM region Kinesin_assoc PF16183.5 CDJ50246.1 - 4.2 7.5 5.4 6 7.0 5.2 1.3 1 1 0 1 1 1 0 Kinesin-associated GREB1 PF15782.5 CDJ50246.1 - 4.9 4.1 17.1 5.5 4.0 17.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3446 PF11928.8 CDJ50246.1 - 5.6 7.3 20.9 0.84 10.0 11.6 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Ndc1_Nup PF09531.10 CDJ50246.1 - 6.1 5.4 18.0 6.6 5.3 18.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4636 PF15468.6 CDJ50246.1 - 8.3 6.0 14.1 11 5.7 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) SUIM_assoc PF16619.5 CDJ50247.1 - 0.027 14.5 5.9 0.027 14.5 5.9 4.4 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 CbiD PF01888.17 CDJ50247.1 - 0.031 13.6 1.8 0.031 13.6 1.8 2.5 2 1 1 3 3 3 0 CbiD DUF775 PF05603.12 CDJ50247.1 - 1.9 8.0 19.1 0.16 11.5 8.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Ndc1_Nup PF09531.10 CDJ50247.1 - 2.2 6.8 16.0 2.5 6.7 16.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNA_pol_Rbc25 PF08292.12 CDJ50247.1 - 7.7 6.8 8.0 2.2 8.5 1.1 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 ETRAMP PF09716.10 CDJ50248.1 - 0.13 12.4 0.1 0.13 12.4 0.1 1.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF2207 PF09972.9 CDJ50248.1 - 0.18 10.6 0.1 0.22 10.3 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MAPEG PF01124.18 CDJ50248.1 - 0.21 11.5 6.4 0.25 11.2 5.5 1.6 1 1 1 2 2 2 0 MAPEG family V_ATPase_I PF01496.19 CDJ50248.1 - 1.2 7.0 10.0 1.2 6.9 10.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Apc15p PF05841.11 CDJ50248.1 - 2.3 9.0 17.6 1.2 10.0 15.6 1.5 1 1 1 2 2 2 0 Apc15p protein PIP5K PF01504.18 CDJ50248.1 - 4.8 6.3 7.7 4.9 6.3 7.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase MAT1 PF06391.13 CDJ50248.1 - 9.4 6.0 19.1 11 5.8 19.1 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Exonuc_VII_L PF02601.15 CDJ50249.1 - 0.2 11.2 41.2 0.31 10.6 41.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PPP4R2 PF09184.11 CDJ50249.1 - 0.44 10.1 23.2 0.52 9.8 23.2 1.2 1 0 0 1 1 1 0 PPP4R2 VIR_N PF15912.5 CDJ50249.1 - 3.8 7.0 23.0 6.4 6.3 23.0 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal CDK5_activator PF03261.15 CDJ50249.1 - 4.5 6.7 36.7 5.6 6.4 36.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein BPL_N PF09825.9 CDJ50249.1 - 6.2 5.8 18.7 8.1 5.4 18.7 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF2151 PF10221.9 CDJ50249.1 - 6.4 5.2 27.9 8.4 4.8 27.9 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator SR-25 PF10500.9 CDJ50250.1 - 0.002 17.8 22.3 0.0023 17.6 22.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ50250.1 - 0.21 12.1 17.1 0.24 12.0 17.1 1.1 1 0 0 1 1 1 0 TCP family transcription factor JUPITER PF17054.5 CDJ50250.1 - 1.4 8.3 12.3 1.6 8.1 12.3 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter TFIIA PF03153.13 CDJ50250.1 - 2.6 7.9 31.2 2.9 7.8 31.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IHABP4_N PF16174.5 CDJ50250.1 - 2.7 8.6 19.8 3 8.4 19.8 1.0 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal IMUP PF15761.5 CDJ50250.1 - 3.3 8.4 19.7 4.6 8.0 19.4 1.5 1 1 0 1 1 1 0 Immortalisation up-regulated protein Velvet PF11754.8 CDJ50250.1 - 4.2 7.2 17.0 4.4 7.2 17.0 1.1 1 0 0 1 1 1 0 Velvet factor CCDC106 PF15794.5 CDJ50250.1 - 6.6 6.4 17.7 8.8 6.0 17.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 eIF-3_zeta PF05091.12 CDJ50250.1 - 7.5 5.4 16.6 7.9 5.3 16.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 CDJ50250.1 - 7.6 6.4 20.0 8.2 6.3 20.0 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ50252.1 - 0.009 15.7 8.7 0.012 15.2 8.7 1.3 1 0 0 1 1 1 1 Spt20 family Roughex PF06020.11 CDJ50252.1 - 0.94 8.5 5.4 1.3 8.0 5.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 CDJ50252.1 - 5.9 5.5 6.3 7.8 5.1 6.3 1.4 1 0 0 1 1 1 0 Presenilin CAF1C_H4-bd PF12265.8 CDJ50253.1 - 3.4e-14 52.8 2.0 4.5e-13 49.2 0.0 3.0 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex RskA PF10099.9 CDJ50253.1 - 1.9e-08 34.8 12.1 1.9e-05 25.0 2.0 11.8 4 4 4 9 9 9 2 Anti-sigma-K factor rskA WD40 PF00400.32 CDJ50253.1 - 1e-05 26.1 1.5 0.79 10.7 0.4 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat SR-25 PF10500.9 CDJ50253.1 - 0.00061 19.5 7.8 0.00061 19.5 7.8 11.2 9 2 0 9 9 9 3 Nuclear RNA-splicing-associated protein Lactamase_B PF00753.27 CDJ50255.1 - 4.9e-09 36.5 0.0 8.8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 CDJ50255.1 - 4.3e-05 23.8 0.1 4.3e-05 23.8 0.1 2.9 3 0 0 3 3 3 1 Alkyl sulfatase C-terminal SseC PF04888.12 CDJ50255.1 - 0.00099 18.8 24.7 0.00099 18.8 24.7 5.3 4 1 0 5 5 1 1 Secretion system effector C (SseC) like family SDA1 PF05285.12 CDJ50255.1 - 0.0015 18.1 18.1 0.0015 18.1 18.1 3.2 2 1 0 2 2 1 1 SDA1 Lactamase_B_2 PF12706.7 CDJ50255.1 - 0.0044 16.6 0.0 0.018 14.6 0.0 2.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2722 PF10846.8 CDJ50255.1 - 0.0057 15.7 5.1 0.0057 15.7 5.1 4.7 3 1 1 4 4 2 2 Protein of unknown function (DUF2722) PNISR PF15996.5 CDJ50255.1 - 0.0058 16.9 35.2 0.0058 16.9 35.2 3.2 2 1 0 2 2 1 1 Arginine/serine-rich protein PNISR BAF1_ABF1 PF04684.13 CDJ50255.1 - 0.23 10.5 60.1 1.1 8.2 24.8 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF572 PF04502.13 CDJ50255.1 - 1.8 8.1 48.5 0.25 10.9 23.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) SPX PF03105.19 CDJ50255.1 - 3.6 7.4 39.0 3.8 7.3 12.4 2.2 2 0 0 2 2 2 0 SPX domain N6_N4_Mtase PF01555.18 CDJ50255.1 - 4.3 7.0 10.8 1.3 8.7 1.3 3.6 2 1 0 2 2 2 0 DNA methylase Utp14 PF04615.13 CDJ50255.1 - 7.2 5.1 60.0 0.2 10.2 25.5 2.1 2 0 0 2 2 2 0 Utp14 protein LMBR1 PF04791.16 CDJ50256.1 - 5.8 5.7 7.9 7.1 5.4 7.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PUB PF09409.10 CDJ50258.1 - 2.4e-23 81.9 0.0 6.4e-23 80.5 0.0 1.6 1 1 0 1 1 1 1 PUB domain APG6 PF04111.12 CDJ50260.1 - 6.5e-43 146.7 0.0 9.4e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CDJ50260.1 - 3.2e-11 43.9 4.3 8.3e-11 42.6 4.3 1.8 1 0 0 1 1 1 1 Apg6 coiled-coil region Lzipper-MIP1 PF14389.6 CDJ50260.1 - 0.036 14.4 5.7 0.067 13.5 2.5 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 PHM7_cyt PF14703.6 CDJ50260.1 - 0.077 13.2 0.3 0.14 12.4 0.3 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF4554 PF15091.6 CDJ50260.1 - 1.5 7.6 3.6 2.8 6.8 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Ctr PF04145.15 CDJ50261.1 - 3.8e-19 69.8 3.5 1.2e-18 68.2 3.5 1.7 1 1 0 1 1 1 1 Ctr copper transporter family SUIM_assoc PF16619.5 CDJ50262.1 - 0.032 14.3 11.6 0.12 12.5 3.7 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ50262.1 - 1.4 8.4 12.8 1.6 8.3 1.8 2.1 2 0 0 2 2 2 0 Spt20 family UQ_con PF00179.26 CDJ50263.1 - 2.4e-51 173.1 0.0 3.3e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ50263.1 - 0.00083 19.1 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ50263.1 - 0.021 15.1 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.11 CDJ50263.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Ank_2 PF12796.7 CDJ50264.1 - 5.9e-16 58.8 7.5 5.6e-10 39.7 2.3 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ50264.1 - 1.2e-13 51.3 0.5 2.3e-07 31.2 0.2 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ50264.1 - 4.8e-13 48.9 4.7 0.0019 18.5 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CDJ50264.1 - 5e-13 49.0 0.3 1.3e-10 41.3 0.7 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ50264.1 - 2.2e-12 46.0 1.2 0.048 14.2 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat TPR_2 PF07719.17 CDJ50264.1 - 1.2e-05 25.0 11.4 0.052 13.7 0.4 4.3 3 1 0 3 3 3 3 Tetratricopeptide repeat Collagen PF01391.18 CDJ50264.1 - 0.00025 20.7 24.4 0.00025 20.7 24.4 2.4 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) TPR_11 PF13414.6 CDJ50264.1 - 0.0055 16.4 3.8 2 8.2 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 CDJ50264.1 - 0.029 14.7 0.1 6.7 7.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ50264.1 - 0.036 14.9 0.6 0.036 14.9 0.6 6.0 5 2 1 6 6 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ50264.1 - 0.081 12.8 7.9 6.1 6.8 0.4 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ50264.1 - 0.6 10.9 6.6 17 6.3 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AF-4 PF05110.13 CDJ50264.1 - 6.8 4.6 13.5 14 3.6 13.5 1.5 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF913 PF06025.12 CDJ50265.1 - 0.0042 16.1 0.2 0.0042 16.1 0.2 6.6 6 1 0 6 6 6 3 Domain of Unknown Function (DUF913) Gti1_Pac2 PF09729.9 CDJ50265.1 - 0.0048 17.0 1.9 0.0048 17.0 1.9 6.3 4 2 0 4 4 4 2 Gti1/Pac2 family SUIM_assoc PF16619.5 CDJ50265.1 - 0.016 15.3 1.1 0.016 15.3 1.1 18.8 13 5 2 16 16 16 0 Unstructured region C-term to UIM in Ataxin3 MecA PF05389.12 CDJ50265.1 - 0.046 13.3 0.2 0.046 13.3 0.2 7.5 6 2 1 7 7 7 0 Negative regulator of genetic competence (MecA) TFIIA PF03153.13 CDJ50266.1 - 0.0036 17.3 17.7 0.0036 17.3 17.7 3.3 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ50266.1 - 0.0074 16.3 6.2 0.0074 16.3 6.2 3.1 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) Fip1 PF05182.13 CDJ50266.1 - 0.021 14.3 1.1 0.055 13.0 1.1 1.7 1 0 0 1 1 1 0 Fip1 motif Caldesmon PF02029.15 CDJ50266.1 - 0.42 9.3 52.6 0.066 12.0 38.7 2.1 2 0 0 2 2 2 0 Caldesmon DcuA_DcuB PF03605.14 CDJ50266.1 - 0.46 9.3 0.0 0.46 9.3 0.0 3.3 3 1 0 3 3 3 0 Anaerobic c4-dicarboxylate membrane transporter NPR3 PF03666.13 CDJ50266.1 - 0.63 8.8 36.2 2.3 6.9 28.4 2.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_11 PF13086.6 CDJ50266.1 - 0.87 9.3 37.2 6.3 6.5 0.3 2.2 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.14 CDJ50266.1 - 2.4 6.3 39.2 1.6 6.9 29.1 2.1 2 0 0 2 2 2 0 CDC45-like protein LAP1C PF05609.12 CDJ50266.1 - 3.1 6.8 42.0 0.5 9.4 1.0 2.3 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) PAT1 PF09770.9 CDJ50266.1 - 7 4.8 77.7 0.38 9.0 9.9 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SART-1 PF03343.13 CDJ50267.1 - 0.44 9.0 7.9 0.58 8.6 7.9 1.3 1 0 0 1 1 1 0 SART-1 family Transket_pyr PF02779.24 CDJ50268.1 - 1.5e-42 145.3 0.0 2.4e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDJ50268.1 - 1.9e-37 127.9 0.1 2.7e-37 127.4 0.1 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CDJ50268.1 - 0.034 14.5 0.1 0.057 13.7 0.1 1.3 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II RabGAP-TBC PF00566.18 CDJ50269.1 - 7.7e-07 29.0 0.5 7.7e-07 29.0 0.5 3.1 4 0 0 4 4 4 1 Rab-GTPase-TBC domain TFIIA PF03153.13 CDJ50269.1 - 0.0054 16.8 11.3 0.0054 16.8 11.3 4.1 4 1 0 4 4 4 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ50270.1 - 0.0015 18.8 6.6 0.0015 18.8 6.6 10.0 3 2 2 5 5 5 2 Anti-sigma-K factor rskA DUF442 PF04273.13 CDJ50271.1 - 0.039 14.0 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) DUF2749 PF10907.8 CDJ50273.1 - 0.0048 17.0 0.0 0.036 14.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2749) HPPK PF01288.20 CDJ50274.1 - 0.075 13.5 0.0 0.085 13.4 0.0 1.1 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) RHH_6 PF16762.5 CDJ50274.1 - 0.2 12.3 0.9 0.28 11.8 0.1 1.8 2 0 0 2 2 2 0 Ribbon-helix-helix domain RPA_interact_M PF14767.6 CDJ50275.1 - 2.6 8.7 13.2 4.4 8.0 0.7 2.7 2 0 0 2 2 2 0 Replication protein A interacting middle SNARE PF05739.19 CDJ50275.1 - 2.9 7.9 7.3 11 6.1 0.6 3.5 3 0 0 3 3 3 0 SNARE domain V-SNARE PF05008.15 CDJ50275.1 - 3.4 8.1 10.6 0.13 12.6 1.7 3.1 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Rx_N PF18052.1 CDJ50276.1 - 0.12 12.7 5.8 2 8.8 0.9 3.1 3 0 0 3 3 3 0 Rx N-terminal domain UCH_1 PF13423.6 CDJ50277.1 - 1.3e-26 94.0 0.0 1.3e-26 94.0 0.0 3.9 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase AAA_23 PF13476.6 CDJ50277.1 - 0.005 17.4 2.9 0.005 17.4 2.9 4.0 4 1 0 4 4 4 1 AAA domain Presenilin PF01080.17 CDJ50277.1 - 0.18 10.5 63.5 0.032 13.0 20.2 4.6 5 0 0 5 5 5 0 Presenilin Zip PF02535.22 CDJ50277.1 - 0.21 10.8 32.4 0.15 11.2 15.6 3.4 3 0 0 3 3 3 0 ZIP Zinc transporter SPX PF03105.19 CDJ50277.1 - 0.57 10.0 64.9 0.14 12.1 21.8 5.2 5 1 0 5 5 5 0 SPX domain Diphthamide_syn PF01866.17 CDJ50278.1 - 1.4e-67 228.3 0.0 1.6e-36 126.4 0.0 3.3 3 0 0 3 3 3 3 Putative diphthamide synthesis protein SOG2 PF10428.9 CDJ50278.1 - 0.058 12.6 34.9 0.1 11.8 34.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 CDJ50279.1 - 0.0046 15.7 56.7 0.01 14.5 41.1 2.4 2 0 0 2 2 2 2 Hamartin protein AF-4 PF05110.13 CDJ50279.1 - 0.37 8.8 79.5 0.063 11.4 15.6 3.1 3 0 0 3 3 3 0 AF-4 proto-oncoprotein Presenilin PF01080.17 CDJ50279.1 - 0.9 8.2 73.2 0.76 8.5 27.4 3.3 3 0 0 3 3 3 0 Presenilin Cwf_Cwc_15 PF04889.12 CDJ50279.1 - 3.2 7.4 50.1 0.33 10.6 15.1 3.9 4 0 0 4 4 4 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.9 CDJ50279.1 - 4.7 5.6 55.9 1.9 6.9 13.6 3.5 3 0 0 3 3 3 0 Macoilin family RNA_pol_Rpc4 PF05132.14 CDJ50280.1 - 1.7e-08 35.0 3.4 1.7e-08 35.0 3.4 6.6 3 3 1 4 4 4 1 RNA polymerase III RPC4 AAA_23 PF13476.6 CDJ50280.1 - 0.012 16.1 10.3 0.012 16.1 10.3 4.4 4 0 0 4 4 4 0 AAA domain Macoilin PF09726.9 CDJ50281.1 - 1.3e-07 30.6 20.0 1.3e-07 30.6 20.0 2.2 2 0 0 2 2 2 2 Macoilin family Ribosomal_S10 PF00338.22 CDJ50281.1 - 9.4e-06 25.8 6.2 1e-05 25.7 0.6 3.2 2 2 1 3 3 3 1 Ribosomal protein S10p/S20e SPX PF03105.19 CDJ50281.1 - 1.5 8.7 53.8 0.81 9.5 18.4 3.2 3 1 0 3 3 3 0 SPX domain Cse1 PF08506.10 CDJ50282.1 - 1.1e-05 24.4 0.1 2.9e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Cse1 Npa1 PF11707.8 CDJ50282.1 - 0.034 13.5 0.1 5.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Ribosome 60S biogenesis N-terminal RIX1 PF08167.12 CDJ50282.1 - 0.78 9.4 4.5 5.3 6.7 0.1 3.6 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis LSM PF01423.22 CDJ50283.1 - 2.5e-22 78.3 0.0 2.9e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDJ50283.1 - 0.001 19.1 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 CDJ50283.1 - 0.05 13.3 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Trypan_PARP PF05887.11 CDJ50285.1 - 3e-06 27.2 36.9 3e-06 27.2 36.9 4.4 1 1 3 4 4 4 1 Procyclic acidic repetitive protein (PARP) DUF1180 PF06679.12 CDJ50285.1 - 0.0044 17.5 2.8 0.0044 17.5 2.8 4.5 1 1 3 4 4 4 1 Protein of unknown function (DUF1180) DUF2201_N PF13203.6 CDJ50285.1 - 0.1 12.2 0.0 0.1 12.2 0.0 3.2 1 1 2 3 3 3 0 Putative metallopeptidase domain Pex24p PF06398.11 CDJ50285.1 - 0.1 11.6 0.0 0.51 9.3 0.0 2.0 1 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Keratin_2_head PF16208.5 CDJ50285.1 - 0.12 12.5 19.7 0.17 12.0 19.7 1.2 1 0 0 1 1 1 0 Keratin type II head KRTAP PF11759.8 CDJ50285.1 - 1.5 9.4 19.9 2.4 8.8 19.9 1.2 1 0 0 1 1 1 0 Keratin-associated matrix DUF2207 PF09972.9 CDJ50285.1 - 1.9 7.2 5.9 3.4 6.3 5.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Serglycin PF04360.12 CDJ50285.1 - 8.8 6.3 20.2 1.8e+04 -5.6 20.2 3.0 1 1 0 1 1 1 0 Serglycin RIO1 PF01163.22 CDJ50287.1 - 1.1e-31 109.9 6.9 8.1e-21 74.5 0.0 3.2 4 0 0 4 4 4 2 RIO1 family Pkinase_fungal PF17667.1 CDJ50287.1 - 9e-05 21.4 0.0 9e-05 21.4 0.0 2.8 2 1 0 2 2 2 1 Fungal protein kinase TFIIA PF03153.13 CDJ50287.1 - 0.00036 20.7 12.8 0.00036 20.7 12.8 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit APH PF01636.23 CDJ50287.1 - 0.00097 19.1 1.7 2.2 8.1 0.0 3.3 3 0 0 3 3 3 2 Phosphotransferase enzyme family NESP55 PF06390.12 CDJ50287.1 - 0.0044 16.7 12.3 0.0044 16.7 12.3 3.4 3 1 0 3 3 3 1 Neuroendocrine-specific golgi protein P55 (NESP55) SR-25 PF10500.9 CDJ50287.1 - 0.0091 15.6 15.4 0.0091 15.6 15.4 5.9 4 1 0 4 4 4 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ50287.1 - 0.0093 15.6 6.5 0.0093 15.6 6.5 2.7 3 0 0 3 3 3 1 Spt20 family Trypan_PARP PF05887.11 CDJ50287.1 - 0.016 15.2 5.4 0.016 15.2 5.4 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SURF6 PF04935.12 CDJ50288.1 - 1.6e-11 44.4 49.5 1.6e-11 44.4 49.5 3.4 1 1 2 3 3 3 1 Surfeit locus protein 6 GHMP_kinases_N PF00288.26 CDJ50288.1 - 0.076 13.3 0.8 0.31 11.3 0.8 1.9 2 0 0 2 2 2 0 GHMP kinases N terminal domain TRAM_LAG1_CLN8 PF03798.16 CDJ50290.1 - 7e-13 48.8 0.2 1.5e-12 47.7 0.2 1.5 1 0 0 1 1 1 1 TLC domain TFIIA PF03153.13 CDJ50290.1 - 0.00031 20.9 68.8 0.018 15.1 27.3 4.4 4 0 0 4 4 4 2 Transcription factor IIA, alpha/beta subunit AAA PF00004.29 CDJ50290.1 - 0.027 14.9 0.3 0.59 10.6 0.5 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SPX PF03105.19 CDJ50290.1 - 0.029 14.3 21.0 0.064 13.2 3.0 3.2 3 0 0 3 3 3 0 SPX domain Velvet PF11754.8 CDJ50290.1 - 0.045 13.7 19.1 0.033 14.1 0.4 3.4 3 0 0 3 3 3 0 Velvet factor Colicin_Pyocin PF01320.18 CDJ50290.1 - 0.05 13.7 0.0 8.1 6.6 0.1 2.5 2 0 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein DDHD PF02862.17 CDJ50290.1 - 0.078 13.1 19.2 0.054 13.6 1.1 3.8 4 0 0 4 4 4 0 DDHD domain Tim54 PF11711.8 CDJ50290.1 - 0.13 11.1 16.2 0.033 13.0 4.2 2.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 MAGE PF01454.19 CDJ50290.1 - 1 9.0 10.7 0.8 9.4 1.0 2.7 2 0 0 2 2 2 0 MAGE family PAT1 PF09770.9 CDJ50290.1 - 5.1 5.3 40.0 0.38 9.0 20.0 2.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SAPS PF04499.15 CDJ50290.1 - 8.9 5.0 16.4 2.3 6.9 5.1 3.1 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein SKA1 PF07160.12 CDJ50291.1 - 0.082 12.7 14.9 0.095 12.5 14.9 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 PAT1 PF09770.9 CDJ50291.1 - 0.4 8.9 23.7 0.42 8.8 23.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 CDJ50291.1 - 0.42 9.6 9.7 0.47 9.4 9.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FAM222A PF15258.6 CDJ50291.1 - 0.69 8.9 30.6 0.83 8.7 30.6 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Senescence_reg PF04520.13 CDJ50291.1 - 0.79 10.5 6.6 0.93 10.3 6.6 1.2 1 0 0 1 1 1 0 Senescence regulator Presenilin PF01080.17 CDJ50291.1 - 0.85 8.3 12.2 1 8.0 12.2 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ50291.1 - 1.1 9.3 6.7 1.3 8.9 6.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Lin-8 PF03353.15 CDJ50291.1 - 1.3 8.5 13.4 1.5 8.3 13.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ribonuc_P_40 PF08584.11 CDJ50291.1 - 1.5 8.0 9.7 1.7 7.8 9.7 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit TMEM51 PF15345.6 CDJ50291.1 - 1.7 8.4 12.6 2.4 8.0 12.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Peptidase_M19 PF01244.21 CDJ50291.1 - 2.3 7.3 6.5 2.6 7.1 6.5 1.1 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Radical_SAM_N PF08497.10 CDJ50291.1 - 2.6 7.2 6.4 3 7.0 6.4 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal ALMT PF11744.8 CDJ50291.1 - 3.4 6.4 7.8 3.8 6.2 7.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 CDJ50291.1 - 4 5.2 11.8 4.5 5.1 11.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Band_3_cyto PF07565.13 CDJ50291.1 - 4.2 7.1 10.4 5 6.8 10.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GET2 PF08690.10 CDJ50291.1 - 6.2 6.4 17.5 7.3 6.2 17.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 ABC2_membrane_3 PF12698.7 CDJ50291.1 - 7.2 5.6 6.2 7.5 5.5 6.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein CLN3 PF02487.17 CDJ50291.1 - 7.4 5.5 10.0 10 5.1 10.0 1.2 1 0 0 1 1 1 0 CLN3 protein DUF4175 PF13779.6 CDJ50291.1 - 8.5 4.1 37.5 10 3.9 37.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Neur_chan_memb PF02932.16 CDJ50291.1 - 8.7 6.3 10.6 10 6.1 10.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 CDJ50291.1 - 9.4 4.8 12.4 10 4.7 12.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Profilin PF00235.19 CDJ50292.1 - 0.013 15.7 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Profilin Pex14_N PF04695.13 CDJ50295.1 - 1.2e-14 55.2 1.3 1.2e-14 55.2 1.3 6.0 4 2 1 5 5 5 2 Peroxisomal membrane anchor protein (Pex14p) conserved region 7TM_GPCR_Srv PF10323.9 CDJ50295.1 - 0.26 10.6 0.0 0.59 9.4 0.0 1.6 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv G-patch PF01585.23 CDJ50296.1 - 1.7e-13 50.2 0.5 6.4e-13 48.4 0.2 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CDJ50296.1 - 6.1e-09 35.8 0.5 6.1e-09 35.8 0.5 3.6 4 1 0 4 4 4 1 G-patch domain Spt20 PF12090.8 CDJ50296.1 - 0.083 12.5 53.9 0.79 9.3 24.3 2.2 2 0 0 2 2 2 0 Spt20 family CDC27 PF09507.10 CDJ50296.1 - 0.52 9.6 49.6 0.67 9.3 49.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SF1-HH PF16275.5 CDJ50297.1 - 0.022 15.1 1.0 0.034 14.5 1.0 1.3 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain TSP_NTD PF17804.1 CDJ50297.1 - 0.045 14.0 3.1 0.051 13.8 3.1 1.1 1 0 0 1 1 1 0 Tail specific protease N-terminal domain DUF5435 PF17503.2 CDJ50297.1 - 0.3 10.8 2.5 0.32 10.7 2.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5435) FTZ PF03867.14 CDJ50297.1 - 0.43 10.1 14.4 0.51 9.8 14.4 1.0 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region PH_13 PF16652.5 CDJ50297.1 - 0.47 10.2 6.8 0.6 9.9 6.8 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain DUF4614 PF15391.6 CDJ50297.1 - 0.72 9.8 15.5 0.77 9.7 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF3138 PF11336.8 CDJ50297.1 - 0.89 8.1 17.4 1.1 7.8 17.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) BAF1_ABF1 PF04684.13 CDJ50297.1 - 1.1 8.2 12.2 1.2 8.1 12.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pex14_N PF04695.13 CDJ50297.1 - 1.2 9.8 13.0 1.4 9.5 13.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CBP4 PF07960.11 CDJ50297.1 - 3.1 7.6 10.8 4.5 7.1 10.8 1.2 1 0 0 1 1 1 0 CBP4 TFIIA PF03153.13 CDJ50297.1 - 3.5 7.5 16.4 4 7.3 16.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC106 PF15794.5 CDJ50297.1 - 5.9 6.5 11.9 8.5 6.0 11.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Velvet PF11754.8 CDJ50297.1 - 9.6 6.1 12.0 9.8 6.0 12.0 1.1 1 0 0 1 1 1 0 Velvet factor TFIIA PF03153.13 CDJ50298.1 - 2e-05 24.8 63.2 0.0056 16.7 23.4 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 CDJ50298.1 - 0.00094 18.2 0.4 0.00094 18.2 0.4 2.3 1 1 1 2 2 2 1 Golgi-body localisation protein domain eIF-3_zeta PF05091.12 CDJ50298.1 - 0.22 10.5 29.0 0.94 8.4 11.1 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Nop53 PF07767.11 CDJ50298.1 - 0.4 10.0 37.6 0.15 11.4 10.8 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) AAA_23 PF13476.6 CDJ50298.1 - 0.94 9.9 18.2 1.2 9.6 2.7 2.3 2 0 0 2 2 2 0 AAA domain DUF572 PF04502.13 CDJ50298.1 - 1.2 8.7 28.3 0.18 11.4 1.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) GREB1 PF15782.5 CDJ50298.1 - 5.9 3.9 40.3 0.45 7.6 3.9 2.1 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer SR-25 PF10500.9 CDJ50299.1 - 2.1e-05 24.2 26.7 3.4e-05 23.6 26.7 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MID_MedPIWI PF18296.1 CDJ50299.1 - 0.0019 18.0 10.9 0.0026 17.6 10.9 1.3 1 0 0 1 1 1 1 MID domain of medPIWI AAA_23 PF13476.6 CDJ50299.1 - 0.011 16.3 11.1 0.014 15.9 11.1 1.3 1 0 0 1 1 1 0 AAA domain SprA-related PF12118.8 CDJ50299.1 - 0.012 14.7 28.1 0.015 14.4 28.1 1.2 1 0 0 1 1 1 0 SprA-related family Smg4_UPF3 PF03467.15 CDJ50299.1 - 0.03 14.4 0.0 0.03 14.4 0.0 2.5 2 1 1 3 3 2 0 Smg-4/UPF3 family PA26 PF04636.13 CDJ50299.1 - 0.077 11.9 9.9 0.097 11.6 9.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Suf PF05843.14 CDJ50299.1 - 0.13 12.2 19.9 0.16 11.9 19.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) XRN_M PF17846.1 CDJ50299.1 - 0.14 11.1 5.5 0.14 11.1 5.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain V_ATPase_I PF01496.19 CDJ50299.1 - 0.16 9.8 8.3 0.17 9.8 8.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 CDJ50299.1 - 0.24 11.5 12.7 0.33 11.0 12.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Velvet PF11754.8 CDJ50299.1 - 0.26 11.2 18.5 0.31 10.9 18.5 1.2 1 0 0 1 1 1 0 Velvet factor Zip PF02535.22 CDJ50299.1 - 0.27 10.4 6.4 0.3 10.3 6.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Endostatin PF06482.11 CDJ50299.1 - 0.31 10.5 13.5 0.35 10.3 13.5 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF572 PF04502.13 CDJ50299.1 - 0.31 10.6 21.0 0.38 10.3 21.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) ABC2_membrane_3 PF12698.7 CDJ50299.1 - 0.32 10.0 1.2 0.34 10.0 1.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein YfhO PF09586.10 CDJ50299.1 - 0.38 8.9 2.8 0.37 9.0 2.8 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO eIF-3_zeta PF05091.12 CDJ50299.1 - 0.5 9.3 16.9 0.57 9.1 16.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM199X PF15814.5 CDJ50299.1 - 0.56 9.2 21.8 0.7 8.9 21.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X rRNA_processing PF08524.11 CDJ50299.1 - 0.77 9.8 26.5 0.038 14.0 20.2 1.8 2 0 0 2 2 2 0 rRNA processing Peptidase_S49_N PF08496.10 CDJ50299.1 - 0.82 9.7 9.4 1.4 8.9 9.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SMYLE_N PF18615.1 CDJ50299.1 - 0.85 9.1 14.6 1.1 8.8 14.6 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Presenilin PF01080.17 CDJ50299.1 - 0.91 8.2 23.7 1.1 7.9 23.7 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CDJ50299.1 - 1.1 7.3 20.9 1.4 7.0 20.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.6 CDJ50299.1 - 1.3 9.5 22.8 1.5 9.4 22.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MDM31_MDM32 PF08118.11 CDJ50299.1 - 1.4 7.5 6.3 1.6 7.3 6.3 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF966 PF06136.13 CDJ50299.1 - 1.5 8.5 18.8 1.7 8.2 18.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Exonuc_VII_L PF02601.15 CDJ50299.1 - 2 7.9 15.0 2.1 7.8 15.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LAP1C PF05609.12 CDJ50299.1 - 2.1 7.3 21.3 2.4 7.2 21.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_S64 PF08192.11 CDJ50299.1 - 2.1 6.7 19.2 2.5 6.5 19.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 Orf78 PF06024.12 CDJ50299.1 - 2.2 8.6 7.5 0.59 10.5 3.6 2.1 2 0 0 2 2 2 0 Orf78 (ac78) MAP70 PF07058.11 CDJ50299.1 - 3.8 6.2 14.2 4.2 6.0 14.2 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 DUF4199 PF13858.6 CDJ50299.1 - 3.8 7.9 6.7 5.9 7.3 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) SAPS PF04499.15 CDJ50299.1 - 3.9 6.1 13.8 4.6 5.9 13.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4661 PF15576.6 CDJ50299.1 - 4.4 7.2 10.9 6 6.7 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) RR_TM4-6 PF06459.12 CDJ50299.1 - 4.5 7.0 20.4 5.9 6.6 20.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Folate_carrier PF01770.18 CDJ50299.1 - 4.6 5.9 9.4 4.4 5.9 9.0 1.3 1 1 0 1 1 1 0 Reduced folate carrier SLC12 PF03522.15 CDJ50299.1 - 5.7 5.9 16.4 6.7 5.6 16.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Hamartin PF04388.12 CDJ50299.1 - 5.7 5.5 19.3 6.3 5.3 19.3 1.1 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 CDJ50299.1 - 5.7 5.5 24.6 6.2 5.4 24.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Raftlin PF15250.6 CDJ50299.1 - 6 5.5 15.5 6.5 5.4 15.5 1.1 1 0 0 1 1 1 0 Raftlin DUF3381 PF11861.8 CDJ50299.1 - 6 6.6 18.5 1.3 8.8 15.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Serinc PF03348.15 CDJ50299.1 - 6.2 5.6 8.8 7.2 5.4 8.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) EMC3_TMCO1 PF01956.16 CDJ50299.1 - 6.3 6.5 12.5 9.2 6.0 12.5 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like GREB1 PF15782.5 CDJ50299.1 - 6.4 3.8 22.8 7.3 3.6 22.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PPP4R2 PF09184.11 CDJ50299.1 - 7.2 6.1 15.2 8.4 5.9 15.2 1.1 1 0 0 1 1 1 0 PPP4R2 TMEM174 PF15029.6 CDJ50299.1 - 7.5 6.2 8.4 11 5.6 8.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 174 Het-C PF07217.11 CDJ50299.1 - 8.7 4.7 9.0 9.8 4.6 9.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C FHIPEP PF00771.20 CDJ50299.1 - 9.1 4.6 9.1 12 4.2 9.1 1.1 1 0 0 1 1 1 0 FHIPEP family DDRGK PF09756.9 CDJ50299.1 - 9.8 5.7 21.4 0.14 11.7 14.1 1.6 2 0 0 2 2 2 0 DDRGK domain Utp14 PF04615.13 CDJ50300.1 - 0.32 9.5 42.3 0.55 8.7 42.3 1.3 1 0 0 1 1 1 0 Utp14 protein PAP2 PF01569.21 CDJ50300.1 - 4 7.2 5.9 0.26 11.1 0.3 2.0 2 0 0 2 2 2 0 PAP2 superfamily Peptidase_S49_N PF08496.10 CDJ50300.1 - 7.2 6.7 15.4 2.2 8.3 10.2 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RskA PF10099.9 CDJ50301.1 - 0.0042 17.4 24.5 0.0051 17.1 24.5 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA ATG22 PF11700.8 CDJ50301.1 - 0.0061 15.2 1.6 0.0058 15.3 1.6 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like EphA2_TM PF14575.6 CDJ50301.1 - 0.018 15.9 1.8 0.031 15.2 1.8 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD20 PF04103.15 CDJ50301.1 - 0.022 14.8 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 CD20-like family TFB6 PF17110.5 CDJ50301.1 - 0.023 14.5 0.3 0.023 14.5 0.3 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Connexin PF00029.19 CDJ50301.1 - 0.024 14.4 1.3 0.022 14.5 1.3 1.1 1 0 0 1 1 1 0 Connexin Synuclein PF01387.17 CDJ50301.1 - 0.076 13.2 5.7 0.09 13.0 5.7 1.1 1 0 0 1 1 1 0 Synuclein DUF2232 PF09991.9 CDJ50301.1 - 0.12 11.6 4.3 0.12 11.5 4.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) MgsA_C PF12002.8 CDJ50301.1 - 0.14 12.1 11.0 0.16 11.9 11.0 1.0 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Spt20 PF12090.8 CDJ50301.1 - 0.16 11.6 30.5 0.17 11.5 30.5 1.1 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ50301.1 - 0.2 10.4 10.0 0.22 10.2 10.0 1.1 1 0 0 1 1 1 0 Presenilin PigN PF04987.14 CDJ50301.1 - 0.21 10.4 2.0 0.19 10.6 2.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) CLN3 PF02487.17 CDJ50301.1 - 0.21 10.6 2.9 0.2 10.7 2.9 1.1 1 0 0 1 1 1 0 CLN3 protein GDE_N PF12439.8 CDJ50301.1 - 0.23 10.9 5.5 0.24 10.8 5.5 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal RAB3GAP2_N PF14655.6 CDJ50301.1 - 0.24 10.6 8.5 0.31 10.2 8.5 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FHIPEP PF00771.20 CDJ50301.1 - 0.26 9.7 8.5 0.26 9.7 8.5 1.0 1 0 0 1 1 1 0 FHIPEP family eIF-3_zeta PF05091.12 CDJ50301.1 - 0.27 10.2 11.0 0.28 10.1 11.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) IHABP4_N PF16174.5 CDJ50301.1 - 0.27 11.8 13.8 0.3 11.7 13.8 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal HA2 PF04408.23 CDJ50301.1 - 0.28 11.5 6.3 0.32 11.3 6.3 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) Serinc PF03348.15 CDJ50301.1 - 0.33 9.8 4.4 0.35 9.7 4.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) 2HCT PF03390.15 CDJ50301.1 - 0.48 9.0 4.4 0.49 9.0 4.4 1.0 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Dala_Dala_lig_N PF01820.21 CDJ50301.1 - 0.48 10.9 2.5 0.55 10.7 2.5 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus TERB2 PF15101.6 CDJ50301.1 - 0.54 10.3 12.9 0.6 10.1 12.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Activator_LAG-3 PF11498.8 CDJ50301.1 - 0.54 9.2 33.4 0.52 9.2 33.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.10 CDJ50301.1 - 0.81 8.3 25.8 1.2 7.8 25.8 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal EOS1 PF12326.8 CDJ50301.1 - 0.81 9.6 3.3 0.81 9.6 3.3 1.1 1 0 0 1 1 1 0 N-glycosylation protein FAM199X PF15814.5 CDJ50301.1 - 0.91 8.5 8.0 0.98 8.4 8.0 1.0 1 0 0 1 1 1 0 Protein family FAM199X Kei1 PF08552.11 CDJ50301.1 - 1 9.2 10.7 1.2 8.9 10.7 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 R_equi_Vir PF05526.11 CDJ50301.1 - 1.1 9.0 10.8 1.3 8.8 10.8 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein OATP PF03137.20 CDJ50301.1 - 1.2 7.3 5.7 1.5 7.0 5.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Coilin_N PF15862.5 CDJ50301.1 - 1.3 8.8 11.5 1.6 8.6 11.5 1.2 1 0 0 1 1 1 0 Coilin N-terminus Pex14_N PF04695.13 CDJ50301.1 - 1.3 9.6 22.9 1.9 9.1 22.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glt_symporter PF03616.14 CDJ50301.1 - 1.4 7.6 3.7 1.5 7.4 3.7 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter AIF_C PF14721.6 CDJ50301.1 - 1.4 9.3 8.6 1.6 9.1 8.6 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TFIIA PF03153.13 CDJ50301.1 - 1.4 8.9 34.3 1.6 8.6 34.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ50301.1 - 1.5 7.0 21.2 1.6 6.9 21.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.17 CDJ50301.1 - 1.5 8.9 8.8 1.7 8.8 8.8 1.1 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.6 CDJ50301.1 - 2 8.4 7.5 1.9 8.4 7.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Suf PF05843.14 CDJ50301.1 - 2.2 8.2 16.7 2.3 8.1 16.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EIF4E-T PF10477.9 CDJ50301.1 - 2.8 6.6 16.3 2.9 6.6 16.3 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DivIC PF04977.15 CDJ50301.1 - 2.8 7.8 18.6 4.5 7.1 18.6 1.3 1 0 0 1 1 1 0 Septum formation initiator Exonuc_VII_L PF02601.15 CDJ50301.1 - 3 7.3 16.8 3.9 7.0 16.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MMR1 PF08505.10 CDJ50301.1 - 3.6 7.8 13.4 3.9 7.7 13.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4179 PF13786.6 CDJ50301.1 - 9.8 6.7 7.5 7.9 7.0 6.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Peptidase_M17_N PF02789.17 CDJ50304.1 - 1.6 8.6 4.9 3.1 7.6 4.9 1.4 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain DUF445 PF04286.12 CDJ50305.1 - 0.00077 19.4 11.3 0.00084 19.3 11.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF445) HI0933_like PF03486.14 CDJ50305.1 - 0.0012 17.6 16.0 0.0015 17.4 16.0 1.1 1 0 0 1 1 1 1 HI0933-like protein IcmF_C PF06744.12 CDJ50305.1 - 0.0042 16.7 9.6 0.0042 16.7 9.6 2.1 1 1 1 2 2 2 1 Type VI secretion protein IcmF C-terminal GerPC PF10737.9 CDJ50305.1 - 0.0055 16.8 20.1 0.0066 16.5 20.1 1.1 1 0 0 1 1 1 1 Spore germination protein GerPC FHIPEP PF00771.20 CDJ50305.1 - 0.0065 15.0 14.5 0.0066 15.0 14.5 1.1 1 0 0 1 1 1 1 FHIPEP family Exonuc_VII_L PF02601.15 CDJ50305.1 - 0.015 14.9 22.5 0.018 14.6 22.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Trigger_C PF05698.14 CDJ50305.1 - 0.037 14.1 23.8 1.9 8.5 23.8 2.1 1 1 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Tam41_Mmp37 PF09139.11 CDJ50305.1 - 0.08 12.4 12.9 0.092 12.2 12.9 1.1 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial MIEAP PF16026.5 CDJ50305.1 - 0.31 11.2 12.5 0.4 10.9 12.5 1.1 1 0 0 1 1 1 0 Mitochondria-eating protein DUF668 PF05003.12 CDJ50305.1 - 0.41 11.1 12.0 2.3 8.7 12.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF668) YpjP PF14005.6 CDJ50305.1 - 0.85 9.7 9.3 1.3 9.1 9.3 1.4 1 0 0 1 1 1 0 YpjP-like protein CemA PF03040.14 CDJ50305.1 - 1.1 9.1 16.7 1.4 8.8 16.7 1.0 1 0 0 1 1 1 0 CemA family Spore_II_R PF09551.10 CDJ50305.1 - 1.2 9.7 11.2 1.8 9.1 11.2 1.3 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) TFIIA PF03153.13 CDJ50305.1 - 1.5 8.7 43.1 1.6 8.7 43.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Minor_tail_Z PF06763.11 CDJ50305.1 - 1.6 8.5 33.5 2.3 8.0 13.3 2.1 1 1 1 2 2 2 0 Prophage minor tail protein Z (GPZ) DUF2924 PF11149.8 CDJ50305.1 - 1.7 9.1 17.6 2.6 8.4 17.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) TERB2 PF15101.6 CDJ50305.1 - 1.7 8.6 16.6 2.2 8.3 16.6 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Inositol_P PF00459.25 CDJ50305.1 - 2.3 7.7 14.2 10 5.5 14.2 1.8 1 1 0 1 1 1 0 Inositol monophosphatase family pP_pnuc_2 PF18166.1 CDJ50305.1 - 2.6 8.1 7.0 1.9e+02 2.1 6.9 2.4 1 1 0 1 1 1 0 Predicted pPIWI-associating nuclease DUF3333 PF11812.8 CDJ50305.1 - 2.6 8.2 10.8 3.6 7.8 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) CLN3 PF02487.17 CDJ50305.1 - 3 6.8 8.2 2.8 6.9 8.2 1.1 1 0 0 1 1 1 0 CLN3 protein Aminopep PF10023.9 CDJ50305.1 - 3.1 7.1 18.8 3.9 6.7 18.8 1.1 1 0 0 1 1 1 0 Putative aminopeptidase AbiH PF14253.6 CDJ50305.1 - 3.4 7.5 8.1 3.9 7.3 8.1 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH ALMT PF11744.8 CDJ50305.1 - 3.4 6.4 10.1 3.8 6.2 10.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MRP-L46 PF11788.8 CDJ50305.1 - 4.6 8.0 17.7 7.9 7.3 17.7 1.4 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Ctr PF04145.15 CDJ50305.1 - 4.9 7.8 7.1 5.7 7.5 7.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Peptidase_S46 PF10459.9 CDJ50305.1 - 6.2 5.3 11.9 7 5.1 11.9 1.0 1 0 0 1 1 1 0 Peptidase S46 RB_A PF01858.17 CDJ50305.1 - 6.2 6.6 18.0 8.9 6.1 18.0 1.2 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain PNGaseA PF12222.8 CDJ50305.1 - 7.1 5.4 14.9 7.8 5.2 14.9 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF3646 PF12362.8 CDJ50305.1 - 7.8 6.9 20.0 3.4e+03 -1.6 20.0 2.8 1 1 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal FapA PF03961.13 CDJ50305.1 - 8.5 4.9 16.7 9.9 4.6 16.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Peptidase_S15 PF02129.18 CDJ50305.1 - 9.4 5.7 11.2 13 5.3 11.2 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PIN_12 PF16289.5 CDJ50305.1 - 9.5 6.7 7.1 13 6.3 7.1 1.2 1 0 0 1 1 1 0 PIN domain DUF572 PF04502.13 CDJ50306.1 - 2e-22 80.3 36.3 8.6e-21 74.9 6.1 4.7 2 2 1 4 4 4 2 Family of unknown function (DUF572) Herpes_capsid PF06112.11 CDJ50306.1 - 0.0023 18.0 9.6 0.0023 18.0 9.6 5.3 4 2 0 4 4 4 1 Gammaherpesvirus capsid protein Cyclin_C_2 PF16899.5 CDJ50307.1 - 0.0057 17.0 0.2 0.042 14.2 0.0 2.2 1 1 1 2 2 2 1 Cyclin C-terminal domain Guanylate_cyc PF00211.20 CDJ50308.1 - 4.3e-06 26.5 0.0 6.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 CDJ50309.1 - 1.1e-11 44.6 0.1 2e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SR-25 PF10500.9 CDJ50311.1 - 0.0055 16.3 12.2 0.0055 16.3 12.2 5.3 5 0 0 5 5 5 4 Nuclear RNA-splicing-associated protein SLC12 PF03522.15 CDJ50312.1 - 0.0027 16.8 17.8 0.16 11.0 11.7 2.3 2 0 0 2 2 2 2 Solute carrier family 12 TFIIA PF03153.13 CDJ50312.1 - 0.0098 15.9 28.8 0.0098 15.9 28.8 4.2 2 1 2 4 4 4 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ50312.1 - 0.019 15.0 0.7 0.019 15.0 0.7 6.9 3 2 2 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 CDJ50312.1 - 5.9 7.9 0.0 5.9 7.9 0.0 4.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) DUF1018 PF06252.12 CDJ50313.1 - 0.15 13.0 3.5 0.19 12.7 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Androgen_recep PF02166.16 CDJ50314.1 - 0.0024 16.8 11.1 0.0024 16.8 11.1 14.6 7 3 6 14 14 14 1 Androgen receptor NICE-1 PF15845.5 CDJ50314.1 - 0.016 16.0 7.1 0.016 16.0 7.1 10.9 9 5 2 11 11 11 0 Cysteine-rich C-terminal 1 family DUF2067 PF09840.9 CDJ50314.1 - 1.4 8.5 2.9 1.3 8.6 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) Ribosomal_60s PF00428.19 CDJ50315.1 - 1.8 9.2 11.8 5 7.8 11.8 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein PI3K_1B_p101 PF10486.9 CDJ50315.1 - 1.9 6.2 36.5 2.2 5.9 36.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RAP1 PF07218.11 CDJ50315.1 - 4.6 5.4 8.1 5.2 5.2 8.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Acetyltransf_7 PF13508.7 CDJ50316.1 - 2.3e-05 24.7 0.1 3.7e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ50316.1 - 2.4e-05 24.2 0.0 4.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ50316.1 - 5.7e-05 23.3 0.0 8.4e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 CDJ50316.1 - 0.00087 19.4 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 CDJ50316.1 - 0.096 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase TFIIA PF03153.13 CDJ50316.1 - 0.41 10.6 10.3 0.8 9.6 10.3 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Arf PF00025.21 CDJ50317.1 - 5.5e-18 65.0 0.0 5.5e-18 65.0 0.0 2.7 3 1 1 4 4 4 1 ADP-ribosylation factor family Roc PF08477.13 CDJ50317.1 - 1.6e-08 34.8 0.0 1.6e-08 34.8 0.0 3.0 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 CDJ50317.1 - 0.034 14.7 4.8 0.049 14.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 CDJ50317.1 - 0.044 12.9 0.2 0.044 12.9 0.2 3.4 2 2 1 3 3 3 0 G-protein alpha subunit SRPRB PF09439.10 CDJ50317.1 - 0.047 13.1 0.0 0.047 13.1 0.0 3.9 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDJ50317.1 - 0.052 12.9 0.0 0.052 12.9 0.0 3.1 3 1 0 3 3 3 0 Gtr1/RagA G protein conserved region G6B PF15096.6 CDJ50317.1 - 6.6 6.5 18.1 1.1 9.0 4.4 2.9 3 0 0 3 3 3 0 G6B family TFIIA PF03153.13 CDJ50318.1 - 0.022 14.8 6.0 0.028 14.4 6.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ50318.1 - 5.2 6.6 12.3 8.5 5.9 12.3 1.2 1 0 0 1 1 1 0 Spt20 family RRM_1 PF00076.22 CDJ50319.1 - 6.9e-37 125.1 0.1 2.3e-17 62.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ50319.1 - 2e-05 24.5 0.0 0.01 15.9 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CDJ50319.1 - 4.2e-05 23.3 0.0 0.0056 16.5 0.0 2.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CDJ50319.1 - 0.0072 16.4 0.0 0.69 10.1 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif DUF4349 PF14257.6 CDJ50320.1 - 0.0032 17.0 1.4 0.0053 16.2 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) FixQ PF05545.11 CDJ50320.1 - 0.0063 16.4 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ IL2 PF00715.17 CDJ50320.1 - 0.043 13.8 0.5 0.067 13.1 0.5 1.3 1 0 0 1 1 1 0 Interleukin 2 MtaB PF12176.8 CDJ50320.1 - 0.13 11.1 5.2 0.18 10.6 5.2 1.2 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Peptidase_S49_N PF08496.10 CDJ50320.1 - 0.17 12.0 5.2 3.1 7.9 4.1 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Nucleic_acid_bd PF13820.6 CDJ50320.1 - 0.19 11.6 1.9 0.39 10.6 1.9 1.4 1 0 0 1 1 1 0 Putative nucleic acid-binding region AMP-binding PF00501.28 CDJ50321.1 - 4.9e-68 229.7 0.0 6.1e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ50321.1 - 0.00013 22.8 1.2 0.00025 21.9 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 CDJ50322.1 - 1.3e-66 224.7 0.0 2.6e-66 223.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ50322.1 - 3.6e-34 118.2 0.7 9e-34 116.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ50322.1 - 0.0049 15.9 0.1 0.0093 14.9 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain LRR_4 PF12799.7 CDJ50323.1 - 1.9e-33 113.9 32.8 2.5e-08 34.1 2.4 7.4 4 2 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ50323.1 - 1e-27 95.7 42.0 8e-10 38.3 0.2 5.3 3 2 3 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 CDJ50323.1 - 5.5e-18 65.1 15.0 6.5e-06 25.7 1.9 4.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 CDJ50323.1 - 0.002 18.0 23.8 0.29 11.3 0.4 7.6 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 CDJ50323.1 - 0.019 15.4 29.5 5.6 7.9 0.2 9.2 7 2 1 8 8 8 0 Leucine Rich Repeat DUF3807 PF12720.7 CDJ50324.1 - 0.038 14.3 35.0 0.045 14.0 35.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Presenilin PF01080.17 CDJ50324.1 - 0.04 12.7 35.0 0.044 12.5 35.0 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CDJ50324.1 - 0.077 11.8 28.3 0.089 11.6 28.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CNDH2_C PF16858.5 CDJ50324.1 - 0.084 12.7 26.3 0.11 12.4 26.3 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term FAM76 PF16046.5 CDJ50324.1 - 0.096 12.0 28.3 0.12 11.7 28.3 1.2 1 0 0 1 1 1 0 FAM76 protein CDC45 PF02724.14 CDJ50324.1 - 0.12 10.6 23.9 0.13 10.5 23.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Bud13 PF09736.9 CDJ50324.1 - 0.15 12.4 28.7 0.23 11.8 28.7 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex CCSAP PF15748.5 CDJ50324.1 - 0.26 11.4 33.3 0.28 11.3 33.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Hid1 PF12722.7 CDJ50324.1 - 0.28 9.3 26.7 0.29 9.2 26.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 CDJ50324.1 - 0.34 9.9 30.6 0.37 9.8 30.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 LTV PF04180.14 CDJ50324.1 - 0.45 10.2 24.4 0.56 9.9 24.4 1.1 1 0 0 1 1 1 0 Low temperature viability protein FAM60A PF15396.6 CDJ50324.1 - 0.46 10.4 23.8 0.55 10.2 23.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4746 PF15928.5 CDJ50324.1 - 0.59 9.5 22.2 0.67 9.3 22.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MMM1 PF10296.9 CDJ50324.1 - 0.61 9.1 17.6 0.74 8.8 17.6 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 MCM_bind PF09739.9 CDJ50324.1 - 0.73 8.2 29.3 0.87 7.9 29.3 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Gti1_Pac2 PF09729.9 CDJ50324.1 - 0.91 9.6 24.4 1.2 9.2 24.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family FancD2 PF14631.6 CDJ50324.1 - 1.1 6.6 14.4 1.3 6.4 14.4 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF2151 PF10221.9 CDJ50324.1 - 1.2 7.6 16.2 1.3 7.6 16.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator AAA_11 PF13086.6 CDJ50324.1 - 1.5 8.5 26.4 1.7 8.3 26.4 1.1 1 0 0 1 1 1 0 AAA domain DDRGK PF09756.9 CDJ50324.1 - 1.5 8.3 41.7 2 7.9 41.7 1.1 1 0 0 1 1 1 0 DDRGK domain DUF4045 PF13254.6 CDJ50324.1 - 1.6 8.3 29.9 1.6 8.3 29.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3295 PF11702.8 CDJ50324.1 - 1.7 7.9 29.4 1.7 7.9 29.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CAC1F_C PF16885.5 CDJ50324.1 - 2.1 7.9 23.0 2.2 7.9 23.0 1.0 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term SRP-alpha_N PF04086.13 CDJ50324.1 - 2.2 8.2 27.6 2.5 8.0 27.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SAPS PF04499.15 CDJ50324.1 - 2.2 7.0 22.4 2.6 6.7 22.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Membralin PF09746.9 CDJ50324.1 - 2.3 7.1 18.6 2.6 7.0 18.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein SAGA-Tad1 PF12767.7 CDJ50324.1 - 2.4 7.9 27.9 2.7 7.7 27.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Apt1 PF10351.9 CDJ50324.1 - 2.4 6.9 19.9 2.7 6.8 19.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain MDM10 PF12519.8 CDJ50324.1 - 2.5 6.8 25.8 2.8 6.7 25.8 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 ALMT PF11744.8 CDJ50324.1 - 2.5 6.8 25.4 2.9 6.6 25.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1387 PF07139.11 CDJ50324.1 - 2.6 7.7 28.3 2.8 7.6 28.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) RR_TM4-6 PF06459.12 CDJ50324.1 - 2.7 7.7 36.1 3.4 7.4 36.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 CDJ50324.1 - 3 6.0 53.8 3.2 5.9 53.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spore_coat_CotO PF14153.6 CDJ50324.1 - 3 7.7 41.4 4.8 7.1 41.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Lin-8 PF03353.15 CDJ50324.1 - 3.2 7.2 36.9 3.4 7.2 36.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Raftlin PF15250.6 CDJ50324.1 - 3.3 6.4 24.8 3.4 6.3 24.8 1.0 1 0 0 1 1 1 0 Raftlin PA26 PF04636.13 CDJ50324.1 - 3.8 6.3 22.8 4.1 6.2 22.8 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Spc7_N PF15402.6 CDJ50324.1 - 4.4 5.4 24.0 5.4 5.1 24.0 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 AUX_IAA PF02309.16 CDJ50324.1 - 4.4 7.1 21.6 4.8 7.0 21.6 1.1 1 0 0 1 1 1 0 AUX/IAA family PNISR PF15996.5 CDJ50324.1 - 4.8 7.4 37.2 5.3 7.3 37.2 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF913 PF06025.12 CDJ50324.1 - 4.9 6.0 19.6 7.3 5.5 19.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4569 PF15133.6 CDJ50324.1 - 4.9 6.8 30.9 5.8 6.5 30.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF4638 PF15472.6 CDJ50324.1 - 5.4 6.7 25.6 6.8 6.3 25.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Neur_chan_memb PF02932.16 CDJ50324.1 - 5.7 6.9 26.5 6.6 6.7 26.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BORG_CEP PF14957.6 CDJ50324.1 - 8.3 7.6 21.6 11 7.1 21.6 1.3 1 0 0 1 1 1 0 Cdc42 effector UMP1 PF05348.11 CDJ50325.1 - 2.9e-15 56.5 0.0 2.9e-15 56.5 0.0 2.8 2 1 0 2 2 1 1 Proteasome maturation factor UMP1 Presenilin PF01080.17 CDJ50325.1 - 0.00035 19.5 10.3 0.00035 19.5 10.3 1.1 1 0 0 1 1 1 1 Presenilin GAGA_bind PF06217.12 CDJ50325.1 - 0.00042 20.7 4.0 0.00045 20.6 4.0 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family DUF913 PF06025.12 CDJ50325.1 - 0.00055 19.0 2.1 0.00063 18.8 2.1 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DDHD PF02862.17 CDJ50325.1 - 0.00083 19.6 7.7 0.0011 19.2 7.7 1.2 1 0 0 1 1 1 1 DDHD domain SID-1_RNA_chan PF13965.6 CDJ50325.1 - 0.0016 16.9 2.2 0.0017 16.9 2.2 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Baculo_PP31 PF05311.11 CDJ50325.1 - 0.0028 17.2 5.8 0.003 17.1 5.8 1.2 1 0 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) CPSF100_C PF13299.6 CDJ50325.1 - 0.0057 16.9 9.3 0.01 16.0 9.3 1.4 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Neur_chan_memb PF02932.16 CDJ50325.1 - 0.0062 16.6 4.8 0.007 16.4 4.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.13 CDJ50325.1 - 0.01 16.5 27.9 0.01 16.5 22.5 2.1 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIP PF07454.11 CDJ50325.1 - 0.015 14.8 15.8 0.021 14.3 15.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Serinc PF03348.15 CDJ50325.1 - 0.016 14.2 3.4 0.018 14.0 3.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF719 PF05334.13 CDJ50325.1 - 0.031 14.5 9.9 0.058 13.6 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) PIP5K PF01504.18 CDJ50325.1 - 0.04 13.2 15.6 0.057 12.6 15.6 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase RR_TM4-6 PF06459.12 CDJ50325.1 - 0.046 13.5 14.6 0.068 13.0 14.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ50325.1 - 0.067 12.2 12.1 0.088 11.8 12.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 CDJ50325.1 - 0.078 11.8 11.2 0.1 11.4 11.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Lin-8 PF03353.15 CDJ50325.1 - 0.087 12.4 16.9 0.13 11.8 16.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BBL5 PF07289.11 CDJ50325.1 - 0.098 11.7 8.9 0.13 11.2 8.9 1.1 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein Tim54 PF11711.8 CDJ50325.1 - 0.11 11.2 14.3 0.17 10.7 14.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CSG2 PF16965.5 CDJ50325.1 - 0.11 11.4 7.7 0.15 11.0 7.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator HCO3_cotransp PF00955.21 CDJ50325.1 - 0.12 11.2 5.0 0.15 10.8 5.0 1.1 1 0 0 1 1 1 0 HCO3- transporter family CDC45 PF02724.14 CDJ50325.1 - 0.12 10.7 10.5 0.14 10.4 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein LMBR1 PF04791.16 CDJ50325.1 - 0.14 11.0 4.8 0.13 11.1 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Band_3_cyto PF07565.13 CDJ50325.1 - 0.15 11.9 14.1 0.23 11.2 14.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4366 PF14283.6 CDJ50325.1 - 0.15 12.1 7.8 0.28 11.2 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CAML PF14963.6 CDJ50325.1 - 0.18 11.9 2.3 0.26 11.4 2.3 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand PBP1_TM PF14812.6 CDJ50325.1 - 0.19 12.1 5.1 0.29 11.5 5.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4638 PF15472.6 CDJ50325.1 - 0.25 11.1 15.3 0.38 10.5 15.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Peroxin-13_N PF04088.13 CDJ50325.1 - 0.25 11.6 8.1 0.46 10.8 8.1 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Borrelia_P83 PF05262.11 CDJ50325.1 - 0.33 9.4 16.8 0.4 9.1 16.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MDM31_MDM32 PF08118.11 CDJ50325.1 - 0.35 9.5 12.0 0.5 9.0 12.0 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins AAA_23 PF13476.6 CDJ50325.1 - 0.4 11.1 18.1 0.48 10.9 18.1 1.2 1 0 0 1 1 1 0 AAA domain DUF4746 PF15928.5 CDJ50325.1 - 0.49 9.8 12.9 0.68 9.3 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PTPRCAP PF15713.5 CDJ50325.1 - 0.64 10.3 17.7 1.1 9.6 17.7 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated eIF-3_zeta PF05091.12 CDJ50325.1 - 0.74 8.7 24.5 0.96 8.4 24.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.22 CDJ50325.1 - 0.75 8.9 7.1 0.99 8.5 7.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Coilin_N PF15862.5 CDJ50325.1 - 0.76 9.6 18.4 1.4 8.7 18.4 1.4 1 0 0 1 1 1 0 Coilin N-terminus NARP1 PF12569.8 CDJ50325.1 - 0.92 8.3 15.3 1.4 7.7 15.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Connexin PF00029.19 CDJ50325.1 - 1 9.1 15.2 1.5 8.5 15.2 1.2 1 0 0 1 1 1 0 Connexin Consortin_C PF15281.6 CDJ50325.1 - 1.1 9.2 5.6 1.9 8.5 5.6 1.3 1 0 0 1 1 1 0 Consortin C-terminus UPF0565 PF10561.9 CDJ50325.1 - 1.2 8.3 9.5 2 7.6 9.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Afi1 PF07792.12 CDJ50325.1 - 1.2 9.6 15.4 1.9 9.0 15.4 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pet20 PF08692.10 CDJ50325.1 - 1.2 9.8 5.5 14 6.4 6.4 2.0 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Membralin PF09746.9 CDJ50325.1 - 1.3 8.0 9.1 1.6 7.7 9.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein Rxt3 PF08642.10 CDJ50325.1 - 1.4 9.7 9.8 3 8.6 9.8 1.5 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Gti1_Pac2 PF09729.9 CDJ50325.1 - 1.6 8.8 14.2 2.6 8.1 14.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family PPL5 PF18168.1 CDJ50325.1 - 1.6 7.9 12.4 2.3 7.4 12.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S64 PF08192.11 CDJ50325.1 - 1.6 7.1 13.2 2.2 6.7 13.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF3405 PF11885.8 CDJ50325.1 - 1.7 7.2 12.5 2.2 6.8 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) AIF_C PF14721.6 CDJ50325.1 - 1.8 8.9 13.7 2.9 8.2 13.7 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3408 PF11888.8 CDJ50325.1 - 2.1 8.5 18.3 3.6 7.7 18.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Kei1 PF08552.11 CDJ50325.1 - 2.2 8.1 15.4 2.6 7.9 12.2 2.0 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 ALMT PF11744.8 CDJ50325.1 - 2.4 6.9 12.1 3.2 6.5 12.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 CDJ50325.1 - 2.4 6.0 19.9 3.2 5.6 19.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EIIBC-GUT_N PF03612.14 CDJ50325.1 - 2.6 7.8 15.3 4.9 6.9 15.3 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2828 PF11443.8 CDJ50325.1 - 2.7 6.0 17.4 3.7 5.5 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3464 PF11947.8 CDJ50325.1 - 2.7 7.7 17.4 5 6.9 17.4 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RICTOR_N PF14664.6 CDJ50325.1 - 3 6.8 9.1 4.3 6.2 9.1 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term XRN_M PF17846.1 CDJ50325.1 - 3.1 6.6 10.6 4.4 6.1 10.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Hid1 PF12722.7 CDJ50325.1 - 3.3 5.7 15.9 4.3 5.3 15.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EPL1 PF10513.9 CDJ50325.1 - 3.4 8.0 19.4 6.8 7.1 19.4 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF5523 PF17661.1 CDJ50325.1 - 3.5 7.2 20.1 5.5 6.6 20.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF2370 PF10176.9 CDJ50325.1 - 4 7.0 9.0 6.6 6.3 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Het-C PF07217.11 CDJ50325.1 - 4.5 5.7 11.0 6 5.3 11.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C MMU163 PF17119.5 CDJ50325.1 - 4.6 6.3 8.2 6.9 5.7 8.2 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Peptidase_U57 PF05582.12 CDJ50325.1 - 5.4 6.2 12.8 8 5.6 12.8 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DDRGK PF09756.9 CDJ50325.1 - 5.5 6.5 27.3 8.7 5.9 27.3 1.2 1 0 0 1 1 1 0 DDRGK domain PepSY_TM PF03929.16 CDJ50325.1 - 6.4 6.4 18.3 9.8 5.8 13.5 2.1 2 0 0 2 2 2 0 PepSY-associated TM region FAM176 PF14851.6 CDJ50325.1 - 6.4 6.4 11.6 10 5.8 11.6 1.3 1 0 0 1 1 1 0 FAM176 family CLN3 PF02487.17 CDJ50325.1 - 7.8 5.4 15.5 11 5.0 15.5 1.1 1 0 0 1 1 1 0 CLN3 protein DUF2126 PF09899.9 CDJ50325.1 - 8.2 4.3 13.9 12 3.8 13.9 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) MAJIN PF15077.6 CDJ50325.1 - 8.5 6.1 12.1 14 5.4 12.1 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein Orf78 PF06024.12 CDJ50325.1 - 9.5 6.6 15.2 37 4.7 15.4 1.8 1 1 0 1 1 1 0 Orf78 (ac78) FAM91_C PF14648.6 CDJ50325.1 - 9.8 4.9 12.7 15 4.3 12.7 1.2 1 0 0 1 1 1 0 FAM91 C-terminus Aldedh PF00171.22 CDJ50326.1 - 7.5e-08 31.3 0.0 0.0003 19.4 0.0 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family PRANC PF09372.10 CDJ50326.1 - 0.089 13.1 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 PRANC domain NTP_transferase PF00483.23 CDJ50327.1 - 0.22 11.0 3.1 0.27 10.8 3.1 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase Auxin_canalis PF05703.11 CDJ50327.1 - 0.24 11.3 15.9 0.3 11.0 15.9 1.0 1 0 0 1 1 1 0 Auxin canalisation Spt20 PF12090.8 CDJ50327.1 - 0.6 9.7 9.7 0.68 9.5 9.7 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ50327.1 - 0.76 9.7 13.2 0.91 9.4 13.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ50327.1 - 0.97 8.4 7.0 1.2 8.2 7.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DEC-1_N PF04625.13 CDJ50328.1 - 0.024 13.7 8.2 0.028 13.5 8.2 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TFIIA PF03153.13 CDJ50328.1 - 0.94 9.4 12.9 1 9.3 12.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ50329.1 - 0.0004 19.3 10.7 0.00043 19.2 10.7 1.2 1 0 0 1 1 1 1 Presenilin Med15 PF09606.10 CDJ50329.1 - 0.032 12.9 40.8 0.04 12.6 40.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GAGA_bind PF06217.12 CDJ50329.1 - 0.051 13.8 14.6 0.054 13.8 14.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Velvet PF11754.8 CDJ50329.1 - 0.066 13.1 11.1 0.085 12.8 11.1 1.3 1 0 0 1 1 1 0 Velvet factor Hydin_ADK PF17213.3 CDJ50329.1 - 0.22 11.8 18.4 0.31 11.3 18.4 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Peptidase_S49_N PF08496.10 CDJ50329.1 - 0.44 10.6 18.6 0.78 9.8 18.6 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PAT1 PF09770.9 CDJ50329.1 - 0.46 8.7 34.3 0.48 8.6 34.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BORG_CEP PF14957.6 CDJ50329.1 - 0.46 11.6 9.4 0.65 11.2 9.4 1.4 1 0 0 1 1 1 0 Cdc42 effector GNT-I PF03071.15 CDJ50329.1 - 0.68 8.6 11.4 0.89 8.3 11.4 1.1 1 0 0 1 1 1 0 GNT-I family RIFIN PF02009.16 CDJ50329.1 - 0.94 9.3 14.8 1.2 9.0 14.8 1.1 1 0 0 1 1 1 0 Rifin AUX_IAA PF02309.16 CDJ50329.1 - 1.3 8.8 10.0 1.6 8.5 10.0 1.3 1 0 0 1 1 1 0 AUX/IAA family Hid1 PF12722.7 CDJ50329.1 - 2.4 6.2 15.1 2.5 6.1 15.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Serinc PF03348.15 CDJ50329.1 - 2.8 6.8 6.6 3.5 6.4 6.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) MIIP PF15734.5 CDJ50329.1 - 4 6.8 19.2 5 6.5 19.2 1.1 1 0 0 1 1 1 0 Migration and invasion-inhibitory eIF-3_zeta PF05091.12 CDJ50329.1 - 5.4 5.9 22.3 6.8 5.5 22.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM222A PF15258.6 CDJ50329.1 - 6.9 5.7 32.3 9.4 5.2 32.3 1.2 1 0 0 1 1 1 0 Protein family of FAM222A Tim54 PF11711.8 CDJ50330.1 - 0.052 12.3 11.6 0.059 12.2 11.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YihI PF04220.12 CDJ50330.1 - 0.087 12.5 14.6 0.1 12.3 14.6 1.0 1 0 0 1 1 1 0 Der GTPase activator (YihI) Swi6_N PF18530.1 CDJ50330.1 - 0.47 10.6 5.7 0.75 10.0 5.7 1.4 1 1 0 1 1 1 0 Swi6 N-terminal domain DUF5345 PF17280.2 CDJ50330.1 - 0.65 10.0 20.4 1.1 9.2 6.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5345) PA26 PF04636.13 CDJ50330.1 - 0.91 8.4 9.3 1 8.2 9.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3402 PF11882.8 CDJ50330.1 - 1.2 8.2 11.8 1.3 8.1 11.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Presenilin PF01080.17 CDJ50330.1 - 1.3 7.7 14.4 1.4 7.6 14.4 1.0 1 0 0 1 1 1 0 Presenilin STAC2_u1 PF16664.5 CDJ50330.1 - 1.6 9.2 10.6 2 8.9 10.6 1.0 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF2828 PF11443.8 CDJ50330.1 - 1.7 6.6 11.1 1.8 6.5 11.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 CDJ50330.1 - 2 7.3 7.2 2.2 7.1 7.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CDJ50330.1 - 2.7 7.7 11.7 3.2 7.5 11.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DOR PF14839.6 CDJ50330.1 - 2.8 7.8 17.5 2.9 7.8 17.5 1.0 1 0 0 1 1 1 0 DOR family MRPL52 PF18699.1 CDJ50330.1 - 3 8.1 20.7 3.9 7.7 20.7 1.1 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Baculo_PP31 PF05311.11 CDJ50330.1 - 3.4 7.1 12.7 4.1 6.8 12.7 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Hydin_ADK PF17213.3 CDJ50330.1 - 3.4 7.9 9.9 4.5 7.5 9.9 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF4407 PF14362.6 CDJ50330.1 - 3.5 6.9 17.0 3.5 6.9 17.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gti1_Pac2 PF09729.9 CDJ50330.1 - 4.6 7.3 9.9 5.3 7.1 9.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DDRGK PF09756.9 CDJ50330.1 - 5 6.7 18.5 6 6.4 18.5 1.1 1 0 0 1 1 1 0 DDRGK domain CCDC53 PF10152.9 CDJ50330.1 - 5.3 7.4 15.3 6.6 7.1 15.3 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Neur_chan_memb PF02932.16 CDJ50330.1 - 5.5 7.0 9.1 6.4 6.8 9.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ50330.1 - 6.4 6.7 34.3 7.8 6.4 34.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec62 PF03839.16 CDJ50330.1 - 7 6.1 9.6 8.4 5.8 9.6 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Band_3_cyto PF07565.13 CDJ50330.1 - 8 6.2 11.2 10 5.9 11.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2040 PF09745.9 CDJ50331.1 - 0.1 12.7 5.0 1.1 9.4 0.2 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) SUIM_assoc PF16619.5 CDJ50331.1 - 3.6 7.7 10.8 11 6.2 0.5 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Serinc PF03348.15 CDJ50332.1 - 0.27 10.1 12.6 0.32 9.9 12.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.17 CDJ50332.1 - 0.67 10.1 23.0 1.1 9.3 23.0 1.3 1 0 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.6 CDJ50332.1 - 1.1 7.6 8.5 1.1 7.6 8.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 K_trans PF02705.16 CDJ50332.1 - 1.5 7.2 4.0 2.6 6.4 4.0 1.4 1 0 0 1 1 1 0 K+ potassium transporter RPE65 PF03055.15 CDJ50332.1 - 1.8 7.6 6.3 2 7.5 6.3 1.1 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein S1-P1_nuclease PF02265.16 CDJ50333.1 - 5.7e-20 72.2 0.0 7.5e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF3605 PF12239.8 CDJ50333.1 - 0.0052 17.1 0.1 0.021 15.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3605) TFIIA PF03153.13 CDJ50334.1 - 0.0003 20.9 32.4 0.00039 20.5 32.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SMYLE_N PF18615.1 CDJ50334.1 - 0.024 14.2 2.4 0.035 13.7 2.4 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain VitD-bind_III PF09164.10 CDJ50334.1 - 0.18 11.8 0.5 1.1 9.3 0.0 2.4 2 1 1 3 3 3 0 Vitamin D binding protein, domain III TERB2 PF15101.6 CDJ50334.1 - 0.2 11.7 6.7 0.41 10.7 6.7 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2722 PF10846.8 CDJ50334.1 - 0.34 9.8 14.7 0.52 9.2 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ50334.1 - 0.4 10.3 22.8 0.67 9.5 22.8 1.3 1 0 0 1 1 1 0 Spt20 family Tho2 PF11262.8 CDJ50334.1 - 0.65 9.1 6.6 1.1 8.4 6.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CLN3 PF02487.17 CDJ50334.1 - 0.7 8.9 2.0 3.3 6.6 2.7 1.6 2 0 0 2 2 2 0 CLN3 protein DUF2203 PF09969.9 CDJ50334.1 - 0.76 10.5 7.6 4.2 8.1 4.4 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Connexin PF00029.19 CDJ50334.1 - 0.98 9.1 2.7 6.8 6.4 4.2 1.5 2 0 0 2 2 2 0 Connexin Activator_LAG-3 PF11498.8 CDJ50334.1 - 1.1 8.2 30.9 1.9 7.4 30.9 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.10 CDJ50334.1 - 1.1 7.9 31.4 1.4 7.6 31.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4834 PF16118.5 CDJ50334.1 - 1.7 9.7 8.5 38 5.3 11.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) WBP-1 PF11669.8 CDJ50334.1 - 2.2 9.0 5.0 1.1e+02 3.5 0.0 2.3 2 0 0 2 2 2 0 WW domain-binding protein 1 PAT1 PF09770.9 CDJ50334.1 - 2.5 6.3 19.2 3.2 5.9 19.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC27 PF09507.10 CDJ50334.1 - 4.6 6.5 22.6 6.3 6.1 22.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pox_G5 PF04599.12 CDJ50334.1 - 6.3 5.7 5.3 9.8 5.1 5.3 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein Spore_III_AF PF09581.10 CDJ50334.1 - 8.7 6.3 10.7 22 5.0 10.7 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Stevor PF17410.2 CDJ50335.1 - 0.0068 16.0 0.4 0.014 14.9 0.4 1.4 1 1 0 1 1 1 1 Subtelomeric Variable Open Reading frame PI3K_P85_iSH2 PF16454.5 CDJ50335.1 - 0.26 10.8 3.5 0.16 11.5 1.4 1.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain GDA1_CD39 PF01150.17 CDJ50336.1 - 7.8e-20 70.9 0.1 2.1e-16 59.6 0.1 3.9 4 0 0 4 4 4 2 GDA1/CD39 (nucleoside phosphatase) family DUF4366 PF14283.6 CDJ50337.1 - 0.0025 17.9 9.0 0.0025 17.9 9.0 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF4366) BAF1_ABF1 PF04684.13 CDJ50337.1 - 0.026 13.6 34.8 0.037 13.1 34.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.9 CDJ50337.1 - 0.071 11.4 59.2 0.084 11.1 59.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF5305 PF17231.2 CDJ50337.1 - 0.14 11.6 3.4 0.29 10.5 0.0 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5305) LAP1C PF05609.12 CDJ50337.1 - 0.17 11.0 46.1 0.18 10.8 46.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2370 PF10176.9 CDJ50337.1 - 0.26 10.9 24.8 0.038 13.6 11.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) GREB1 PF15782.5 CDJ50337.1 - 1.5 5.8 43.2 1.8 5.5 43.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1387 PF07139.11 CDJ50337.1 - 5.2 6.7 45.6 7.4 6.2 45.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Dapper PF15268.6 CDJ50337.1 - 6.8 5.4 46.8 8.3 5.1 46.8 1.2 1 0 0 1 1 1 0 Dapper CAC1F_C PF16885.5 CDJ50337.1 - 7.5 6.1 33.0 9.7 5.7 33.0 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term RskA PF10099.9 CDJ50338.1 - 0.0092 16.3 9.1 0.011 16.0 9.1 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Dala_Dala_lig_N PF01820.21 CDJ50338.1 - 0.3 11.6 2.9 0.43 11.1 2.9 1.4 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus IHABP4_N PF16174.5 CDJ50338.1 - 0.37 11.4 23.2 0.42 11.2 23.2 1.0 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal BAF1_ABF1 PF04684.13 CDJ50338.1 - 0.38 9.8 15.6 0.43 9.6 15.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DcuC PF03606.15 CDJ50338.1 - 0.58 8.5 2.8 0.61 8.5 2.8 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier HA2 PF04408.23 CDJ50338.1 - 0.62 10.4 9.6 0.72 10.2 9.6 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) FAM60A PF15396.6 CDJ50338.1 - 0.88 9.5 15.7 0.97 9.4 15.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A THOC2_N PF16134.5 CDJ50338.1 - 0.93 8.0 14.0 0.95 8.0 14.0 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus CCB2_CCB4 PF11152.8 CDJ50338.1 - 0.94 8.7 6.6 1.1 8.6 6.6 1.0 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 Zip PF02535.22 CDJ50338.1 - 0.95 8.6 10.1 0.95 8.6 10.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4366 PF14283.6 CDJ50338.1 - 1 9.4 8.9 1.3 9.1 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TMEM154 PF15102.6 CDJ50338.1 - 1 9.2 5.9 1.3 8.9 5.9 1.1 1 0 0 1 1 1 0 TMEM154 protein family DcuA_DcuB PF03605.14 CDJ50338.1 - 1.3 7.9 4.4 1.4 7.8 4.4 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter R_equi_Vir PF05526.11 CDJ50338.1 - 1.5 8.6 9.7 1.8 8.4 9.7 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein HCO3_cotransp PF00955.21 CDJ50338.1 - 1.5 7.5 9.4 1.6 7.5 9.4 1.0 1 0 0 1 1 1 0 HCO3- transporter family MRI PF15325.6 CDJ50338.1 - 1.8 9.7 7.1 2 9.5 7.1 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection SMYLE_N PF18615.1 CDJ50338.1 - 2.3 7.7 11.8 2.3 7.7 11.8 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PigN PF04987.14 CDJ50338.1 - 2.5 6.9 6.9 2.8 6.7 6.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Kei1 PF08552.11 CDJ50338.1 - 2.6 7.9 14.2 2.7 7.8 14.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ureide_permease PF07168.11 CDJ50338.1 - 3.7 6.2 6.8 4 6.1 6.8 1.1 1 0 0 1 1 1 0 Ureide permease NPR3 PF03666.13 CDJ50338.1 - 4.1 6.1 15.8 4.4 6.0 15.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 CDJ50338.1 - 4.6 6.9 12.0 5 6.8 12.0 1.1 1 0 0 1 1 1 0 Connexin Rtf2 PF04641.12 CDJ50338.1 - 4.7 6.5 18.8 5.1 6.4 18.8 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Glycophorin_A PF01102.18 CDJ50338.1 - 5.4 7.3 13.1 15 5.9 13.1 1.7 1 1 0 1 1 1 0 Glycophorin A PIP5K PF01504.18 CDJ50338.1 - 5.6 6.1 12.6 6.2 6.0 12.6 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Suf PF05843.14 CDJ50338.1 - 5.9 6.8 21.7 6.6 6.6 21.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3499 PF12005.8 CDJ50338.1 - 6.5 7.4 10.0 9.7 6.8 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) Pex14_N PF04695.13 CDJ50338.1 - 7 7.3 27.4 8.4 7.0 27.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serinc PF03348.15 CDJ50338.1 - 9 5.1 10.5 9.4 5.0 10.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spt20 PF12090.8 CDJ50340.1 - 0.00026 20.7 11.5 0.00026 20.7 11.5 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ50340.1 - 0.00027 20.0 7.5 0.00027 20.0 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ50340.1 - 0.019 15.0 9.3 0.02 14.9 9.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 CDJ50340.1 - 0.11 13.1 17.7 0.16 12.7 17.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Roughex PF06020.11 CDJ50340.1 - 1.2 8.1 6.6 1.2 8.1 6.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein WBP-1 PF11669.8 CDJ50340.1 - 1.4 9.6 6.9 2.1 9.0 6.9 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 Rrn6 PF10214.9 CDJ50340.1 - 2.9 6.3 11.0 3.6 5.9 11.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Serinc PF03348.15 CDJ50341.1 - 0.0018 17.3 0.5 0.0019 17.2 0.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) TFIIA PF03153.13 CDJ50341.1 - 0.0021 18.1 9.4 0.0021 18.1 9.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ50341.1 - 0.0035 17.7 8.4 0.0044 17.3 8.4 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA MRP-L28 PF09812.9 CDJ50341.1 - 0.066 13.3 9.1 0.08 13.1 9.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Spt20 PF12090.8 CDJ50341.1 - 0.069 12.8 20.0 0.086 12.4 20.0 1.1 1 0 0 1 1 1 0 Spt20 family Stevor PF17410.2 CDJ50341.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CLN3 PF02487.17 CDJ50341.1 - 0.18 10.8 1.2 0.22 10.5 1.2 1.2 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 CDJ50341.1 - 0.39 9.4 4.4 0.48 9.1 4.4 1.1 1 0 0 1 1 1 0 Presenilin Tic110 PF16940.5 CDJ50341.1 - 0.78 8.1 5.3 1 7.8 5.3 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter PNISR PF15996.5 CDJ50343.1 - 0.44 10.8 39.9 0.54 10.5 39.9 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Presenilin PF01080.17 CDJ50343.1 - 0.51 9.0 34.5 0.51 9.0 34.5 1.1 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 CDJ50343.1 - 0.82 9.0 29.3 0.94 8.8 29.3 1.1 1 0 0 1 1 1 0 SDA1 Caldesmon PF02029.15 CDJ50343.1 - 3.7 6.2 35.9 4 6.1 35.9 1.1 1 0 0 1 1 1 0 Caldesmon Stevor PF17410.2 CDJ50343.1 - 5.5 6.5 11.3 6.8 6.1 11.3 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF5523 PF17661.1 CDJ50343.1 - 8.1 6.0 33.0 12 5.5 33.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RVT_1 PF00078.27 CDJ50345.1 - 2.7e-10 40.1 0.0 5.1e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CLTH PF10607.9 CDJ50348.1 - 1.3e-23 83.5 0.5 1.8e-23 83.0 0.5 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF1858 PF08984.11 CDJ50348.1 - 0.13 12.4 0.2 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) LisH PF08513.11 CDJ50348.1 - 0.15 12.0 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 LisH SGL PF08450.12 CDJ50348.1 - 0.2 11.2 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region BTB PF00651.31 CDJ50349.1 - 4.8e-08 33.2 0.1 1.5e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Dus PF01207.17 CDJ50350.1 - 2.7e-35 122.0 0.0 4.3e-29 101.6 0.0 3.0 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF1768 PF08719.11 CDJ50351.1 - 0.01 16.1 0.8 0.23 11.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1768) Met_10 PF02475.16 CDJ50352.1 - 3e-43 147.9 0.0 2.9e-42 144.7 0.0 2.1 1 1 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 CDJ50352.1 - 0.0039 16.4 0.1 0.0059 15.8 0.1 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.10 CDJ50352.1 - 0.0066 16.0 0.2 0.018 14.6 0.0 1.8 3 0 0 3 3 3 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 CDJ50352.1 - 0.014 16.1 0.1 0.039 14.7 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain SAM_MT PF04445.13 CDJ50352.1 - 0.023 14.1 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Methyltransf_23 PF13489.6 CDJ50352.1 - 0.056 13.3 0.1 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ50352.1 - 0.06 13.0 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MethyltransfD12 PF02086.15 CDJ50352.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase SARAF PF06682.12 CDJ50353.1 - 0.01 15.6 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CCDC53 PF10152.9 CDJ50353.1 - 1.4 9.3 4.1 14 6.1 1.7 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF3040 PF11239.8 CDJ50353.1 - 1.5 9.1 5.8 4.9 7.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DnaJ PF00226.31 CDJ50355.1 - 7.3e-15 54.9 0.0 2.3e-14 53.3 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.13 CDJ50355.1 - 0.00031 20.9 12.9 0.00031 20.9 12.9 5.9 3 1 2 5 5 5 1 Transcription factor IIA, alpha/beta subunit Wzy_C PF04932.15 CDJ50355.1 - 0.083 12.5 0.1 18 4.9 0.0 2.5 2 0 0 2 2 2 0 O-Antigen ligase YL1 PF05764.13 CDJ50355.1 - 0.32 11.1 0.0 0.32 11.1 0.0 6.7 5 2 1 6 6 6 0 YL1 nuclear protein Cyt-b5 PF00173.28 CDJ50356.1 - 4.3e-22 78.1 0.1 5.7e-22 77.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4366 PF14283.6 CDJ50356.1 - 0.0061 16.6 0.0 0.0079 16.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Thyroglobulin_1 PF00086.18 CDJ50356.1 - 0.071 12.8 1.2 0.15 11.8 1.2 1.5 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat PspB PF06667.12 CDJ50356.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein B DEAD PF00270.29 CDJ50357.1 - 7e-42 143.2 0.0 1.3e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ50357.1 - 6.9e-27 94.0 0.0 1.6e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain mIF3 PF14877.6 CDJ50357.1 - 0.026 14.2 0.2 0.061 13.0 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial translation initiation factor cNMP_binding PF00027.29 CDJ50358.1 - 4e-18 65.3 0.0 1.1e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 CDJ50358.1 - 0.051 12.8 13.4 0.075 12.3 13.4 1.2 1 0 0 1 1 1 0 Ion transport protein EF-hand_6 PF13405.6 CDJ50359.1 - 1.4e-09 37.1 1.9 1.6e-07 30.7 0.1 3.3 3 1 1 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 CDJ50359.1 - 1.3e-08 35.1 0.6 1.4e-06 28.6 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ50359.1 - 1.4e-08 33.7 1.5 3.4e-06 26.2 0.1 3.7 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 CDJ50359.1 - 2.5e-06 27.2 0.4 0.0018 18.1 0.0 2.8 2 1 2 4 4 4 3 EF-hand domain pair DUF3008 PF11450.8 CDJ50359.1 - 0.0066 16.6 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknwon function (DUF3008) DUF2599 PF10783.9 CDJ50359.1 - 0.063 13.9 0.2 8.8 7.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2599) EF-hand_9 PF14658.6 CDJ50359.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain LEM PF03020.15 CDJ50359.1 - 0.15 11.7 0.2 1 9.0 0.2 2.1 2 0 0 2 2 2 0 LEM domain EF-hand_5 PF13202.6 CDJ50359.1 - 0.2 11.2 2.9 4.9 6.8 0.1 3.2 3 0 0 3 3 3 0 EF hand Mito_carr PF00153.27 CDJ50360.1 - 1.3e-33 114.7 3.0 2.8e-13 49.6 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S8 PF00410.19 CDJ50361.1 - 3.2e-21 75.6 0.0 3.7e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 SLBP_RNA_bind PF15247.6 CDJ50362.1 - 4.6e-23 81.1 1.7 9.8e-23 80.1 1.7 1.6 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Ski2_N PF17911.1 CDJ50363.1 - 0.096 12.5 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Ski2 N-terminal region Telomere_Sde2_2 PF13297.6 CDJ50364.1 - 1.5e-16 59.7 1.7 2.3e-16 59.2 0.3 2.1 2 0 0 2 2 2 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 CDJ50364.1 - 4.9e-12 46.0 3.8 4.9e-12 46.0 3.8 3.3 2 1 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain WD40 PF00400.32 CDJ50365.1 - 1.3e-15 57.5 4.3 3.4e-05 24.5 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ50365.1 - 1.7e-06 28.2 0.0 0.047 14.0 0.0 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain MMR_HSR1 PF01926.23 CDJ50366.1 - 2.8e-14 53.1 0.0 4.6e-14 52.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ50366.1 - 4.8e-07 29.4 0.0 2e-06 27.4 0.1 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ50366.1 - 2.9e-06 27.4 0.1 0.00038 20.6 0.2 2.2 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CDJ50366.1 - 1.4e-05 25.1 0.0 0.02 14.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CDJ50366.1 - 0.00024 20.5 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 CDJ50366.1 - 0.0068 16.8 0.0 0.0097 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 CDJ50366.1 - 0.017 15.3 0.1 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CDJ50366.1 - 0.017 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CDJ50366.1 - 0.035 14.6 0.0 0.057 13.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter MOLO1 PF17175.4 CDJ50367.1 - 5.6e-10 39.4 0.0 7.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 Tweety PF04906.13 CDJ50368.1 - 0.0005 18.9 1.3 0.0005 18.9 1.3 3.0 3 0 0 3 3 3 1 Tweety baeRF_family10 PF18854.1 CDJ50368.1 - 0.0084 16.4 0.4 0.026 14.8 0.4 1.8 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Host_attach PF10116.9 CDJ50368.1 - 0.2 12.2 2.6 0.66 10.6 2.6 1.8 1 0 0 1 1 1 0 Protein required for attachment to host cells TraT PF05818.12 CDJ50368.1 - 6.6 6.4 9.0 1.3 8.6 0.2 2.5 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein ABC_tran PF00005.27 CDJ50369.1 - 2.6e-32 112.2 0.2 3.8e-21 76.0 0.0 5.6 6 1 0 6 6 5 2 ABC transporter ABC_membrane PF00664.23 CDJ50369.1 - 6.4e-14 52.3 0.3 1.3e-09 38.1 0.0 3.8 4 0 0 4 4 4 2 ABC transporter transmembrane region DUF2722 PF10846.8 CDJ50369.1 - 4.1e-06 26.0 4.1 4.1e-06 26.0 4.1 9.5 7 3 0 8 8 4 2 Protein of unknown function (DUF2722) RsgA_GTPase PF03193.16 CDJ50369.1 - 9e-06 25.7 0.4 0.089 12.7 0.0 3.2 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CDJ50369.1 - 7.8e-05 22.3 7.8 0.0031 17.2 0.0 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ50369.1 - 0.00045 20.3 0.0 0.38 10.9 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 CDJ50369.1 - 0.00051 20.0 1.0 7.7 6.2 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 CDJ50369.1 - 0.014 15.5 0.4 0.014 15.5 0.4 5.6 5 1 0 5 5 4 0 Dynamin family AAA_22 PF13401.6 CDJ50369.1 - 0.026 14.8 0.6 20 5.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF3742 PF12553.8 CDJ50369.1 - 0.071 13.2 5.0 0.25 11.5 0.0 4.6 6 0 0 6 6 5 0 Protein of unknown function (DUF3742) DUF87 PF01935.17 CDJ50369.1 - 0.55 10.3 4.2 14 5.7 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 CDJ50369.1 - 1.6 9.2 0.0 1.6 9.2 0.0 7.6 8 1 0 8 8 5 0 AAA domain Aldo_ket_red PF00248.21 CDJ50370.1 - 9.7e-26 90.6 0.0 4.4e-25 88.5 0.0 2.1 2 1 0 2 2 2 1 Aldo/keto reductase family Spt20 PF12090.8 CDJ50371.1 - 0.026 14.1 35.1 0.012 15.3 28.3 2.2 1 1 1 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ50371.1 - 0.037 13.7 15.2 0.083 12.5 15.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2967 PF11179.8 CDJ50371.1 - 0.08 11.0 15.1 0.12 10.4 15.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) CDRT4 PF15213.6 CDJ50371.1 - 1.5 9.4 5.8 0.31 11.7 1.8 1.9 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein DEAD PF00270.29 CDJ50374.1 - 8.4e-31 107.1 0.0 8.4e-27 94.0 0.0 2.8 2 1 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CDJ50374.1 - 0.00011 22.3 0.0 0.00018 21.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ50375.1 - 1.4e-23 83.4 0.0 3.6e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HALZ PF02183.18 CDJ50376.1 - 0.011 15.9 7.5 0.066 13.5 0.7 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 CDJ50376.1 - 0.056 13.8 0.5 0.056 13.8 0.5 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMCO5 PF14992.6 CDJ50376.1 - 0.068 12.7 8.7 0.16 11.5 8.7 1.5 1 1 0 1 1 1 0 TMCO5 family Scaffolding_pro PF11418.8 CDJ50376.1 - 0.075 13.6 1.9 4.8 7.8 0.1 3.0 2 1 1 3 3 3 0 Phi29 scaffolding protein DUF3584 PF12128.8 CDJ50376.1 - 0.093 10.2 13.8 0.12 9.9 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cluap1 PF10234.9 CDJ50376.1 - 0.2 11.0 9.9 0.079 12.3 7.3 1.6 1 1 1 2 2 2 0 Clusterin-associated protein-1 Atg14 PF10186.9 CDJ50376.1 - 0.52 9.3 10.3 0.59 9.2 10.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 CDJ50376.1 - 0.64 7.9 3.7 0.75 7.6 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hemerythrin PF01814.23 CDJ50376.1 - 0.75 10.4 7.9 1.2 9.8 7.9 1.4 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain DivIVA PF05103.13 CDJ50376.1 - 0.76 9.9 14.7 1.9 8.6 14.6 1.7 1 1 0 1 1 1 0 DivIVA protein ATG16 PF08614.11 CDJ50376.1 - 0.97 9.6 23.0 0.25 11.6 14.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) YabA PF06156.13 CDJ50376.1 - 1.3 9.7 11.6 0.64 10.7 7.1 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 CDJ50376.1 - 2.2 7.8 9.9 2.7 7.5 9.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 CDJ50376.1 - 6.3 7.3 18.7 2.6 8.5 3.7 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 CDJ50376.1 - 6.6 6.0 16.5 9.4 5.5 16.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cluap1 PF10234.9 CDJ50377.1 - 1.6e-07 31.0 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 MdcG PF10620.9 CDJ50377.1 - 0.16 11.7 3.0 0.24 11.1 3.0 1.4 1 1 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Peptidase_C15 PF01470.17 CDJ50378.1 - 0.16 12.1 0.0 0.45 10.7 0.0 1.7 2 0 0 2 2 2 0 Pyroglutamyl peptidase RNA_pol PF00940.19 CDJ50380.1 - 1.2e-135 452.6 0.0 4.4e-135 450.7 0.0 2.1 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CDJ50380.1 - 2e-12 47.2 7.8 4.4e-09 36.2 0.4 8.1 5 2 2 7 7 7 3 DNA-directed RNA polymerase N-terminal YgbB PF02542.16 CDJ50381.1 - 1.3e-46 158.7 1.0 2.9e-41 141.3 0.9 2.2 2 0 0 2 2 2 2 YgbB family SH3_4 PF06347.13 CDJ50381.1 - 0.11 12.3 1.9 14 5.6 0.5 2.9 2 0 0 2 2 2 0 Bacterial SH3 domain SR-25 PF10500.9 CDJ50381.1 - 6.6 6.3 6.2 13 5.4 6.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4692 PF15763.5 CDJ50381.1 - 6.7 7.2 6.9 0.82 10.1 1.1 2.1 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) RR_TM4-6 PF06459.12 CDJ50382.1 - 5.3 6.8 32.2 3.6 7.3 23.4 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DEK_C PF08766.11 CDJ50384.1 - 3.8e-06 26.7 1.4 6.3e-06 26.0 1.4 1.5 1 0 0 1 1 1 1 DEK C terminal domain PhageMin_Tail PF10145.9 CDJ50384.1 - 0.013 15.4 0.3 0.013 15.3 0.3 1.0 1 0 0 1 1 1 0 Phage-related minor tail protein Nucleopor_Nup85 PF07575.13 CDJ50384.1 - 0.041 12.5 0.4 0.039 12.5 0.4 1.0 1 0 0 1 1 1 0 Nup85 Nucleoporin Adaptin_binding PF10199.9 CDJ50384.1 - 0.15 12.7 5.3 0.18 12.4 5.3 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SID-1_RNA_chan PF13965.6 CDJ50385.1 - 9.6 4.5 7.9 19 3.5 7.9 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SOG2 PF10428.9 CDJ50386.1 - 2.2 7.4 15.7 2.6 7.1 15.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SWI-SNF_Ssr4 PF08549.10 CDJ50386.1 - 5.5 5.5 16.3 6.2 5.3 16.3 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) WD40 PF00400.32 CDJ50387.1 - 1.5e-18 66.8 33.2 2.6e-05 24.9 0.1 8.9 9 0 0 9 9 9 5 WD domain, G-beta repeat PRP4 PF08799.11 CDJ50387.1 - 1.8e-11 43.4 0.9 4e-11 42.3 0.9 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 CDJ50387.1 - 3.2e-10 40.2 0.0 0.057 13.7 0.0 5.2 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain EPL1 PF10513.9 CDJ50387.1 - 7.4 6.9 13.2 7.3 7.0 1.4 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like Solute_trans_a PF03619.16 CDJ50388.1 - 1.9e-06 27.6 3.8 6.9e-05 22.5 1.7 2.2 2 0 0 2 2 2 2 Organic solute transporter Ostalpha TPR_1 PF00515.28 CDJ50391.1 - 4.1e-08 32.7 0.1 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ50391.1 - 8e-08 31.8 0.0 0.022 14.8 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ50391.1 - 6.2e-06 26.4 0.2 0.0025 18.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ50391.1 - 2.2e-05 24.1 0.5 0.0017 18.0 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 CDJ50391.1 - 6.5e-05 23.4 0.0 0.00015 22.2 0.0 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ50391.1 - 0.00028 21.5 0.0 0.88 10.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 CDJ50391.1 - 0.00067 19.7 0.1 0.0079 16.2 0.0 2.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 CDJ50391.1 - 0.0008 20.0 0.0 0.01 16.5 0.0 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ50391.1 - 0.0016 18.7 1.0 0.013 15.7 1.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CDJ50391.1 - 0.0017 18.9 0.1 0.49 11.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ50391.1 - 0.0039 17.1 0.3 0.78 9.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ50391.1 - 0.12 12.7 0.3 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ50391.1 - 0.33 10.9 1.9 1.4 8.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Aha1_N PF09229.11 CDJ50392.1 - 1.4e-12 48.0 0.7 2.8e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal TPR_1 PF00515.28 CDJ50392.1 - 0.016 15.0 0.0 0.11 12.4 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ50392.1 - 0.45 11.5 0.2 0.45 11.5 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DAG_kinase_N PF14513.6 CDJ50393.1 - 0.006 16.8 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus ubiquitin PF00240.23 CDJ50393.1 - 0.012 15.3 0.0 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin family EF-hand_6 PF13405.6 CDJ50393.1 - 0.017 15.0 0.1 0.19 11.7 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain DWNN PF08783.11 CDJ50393.1 - 0.042 14.1 0.0 6.3 7.2 0.0 2.6 3 0 0 3 3 3 0 DWNN domain ACOX PF01756.19 CDJ50394.1 - 5e-06 26.2 0.1 5e-06 26.2 0.1 3.3 3 1 1 4 4 4 1 Acyl-CoA oxidase TFIIA PF03153.13 CDJ50394.1 - 0.00082 19.5 30.8 0.0011 19.0 30.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ50394.1 - 0.03 13.9 11.2 0.043 13.4 11.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1631 PF07793.11 CDJ50394.1 - 0.14 10.5 23.5 0.17 10.3 23.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF1980 PF09323.10 CDJ50394.1 - 0.19 11.6 2.1 0.29 11.0 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Med15 PF09606.10 CDJ50394.1 - 0.41 9.3 35.0 0.56 8.8 35.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 CDJ50394.1 - 0.55 8.9 5.6 0.7 8.6 5.6 1.3 1 0 0 1 1 1 0 Presenilin KAsynt_C_assoc PF16197.5 CDJ50394.1 - 0.85 10.1 4.5 0.47 10.9 1.5 2.0 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension PAT1 PF09770.9 CDJ50394.1 - 1.3 7.2 14.9 1.6 6.9 14.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cadherin_C PF01049.17 CDJ50394.1 - 2.9 8.2 8.2 5.8 7.2 7.1 2.0 2 0 0 2 2 2 0 Cadherin cytoplasmic region DUF1645 PF07816.11 CDJ50394.1 - 7 7.2 12.8 0.29 11.7 7.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) GREB1 PF15782.5 CDJ50394.1 - 7.2 3.6 17.1 8.1 3.4 17.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer IMUP PF15761.5 CDJ50395.1 - 0.0034 18.0 19.3 0.0034 18.0 19.3 1.9 1 1 0 2 2 2 1 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ50395.1 - 0.61 9.7 39.1 1.6 8.3 39.1 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 CDJ50395.1 - 0.82 10.3 17.5 1 10.0 17.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SprA-related PF12118.8 CDJ50395.1 - 1.7 7.7 27.5 2.3 7.3 27.5 1.2 1 0 0 1 1 1 0 SprA-related family Velvet PF11754.8 CDJ50395.1 - 2.1 8.2 16.7 2.1 8.2 16.7 1.1 1 0 0 1 1 1 0 Velvet factor Spem1 PF15670.5 CDJ50395.1 - 4.1 6.9 20.6 2.2 7.8 19.0 1.3 1 1 0 1 1 1 0 Spermatid maturation protein 1 RAP1 PF07218.11 CDJ50395.1 - 5.5 5.2 10.1 6 5.0 10.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF913 PF06025.12 CDJ50395.1 - 6 5.7 14.0 6.2 5.7 14.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PA26 PF04636.13 CDJ50395.1 - 6.7 5.5 14.2 7.4 5.4 14.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Dsh_C PF12316.8 CDJ50395.1 - 8 6.8 19.5 8.1 6.8 19.5 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal zf-CCHC PF00098.23 CDJ50396.1 - 0.0018 18.3 2.0 0.0018 18.3 2.0 2.1 3 0 0 3 3 3 1 Zinc knuckle RT_RNaseH_2 PF17919.1 CDJ50397.1 - 9.7e-25 86.5 0.1 1.8e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ50397.1 - 2.4e-20 72.8 0.1 4.8e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ50397.1 - 2.8e-17 63.0 0.0 5.1e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ50397.1 - 1.8e-10 41.0 0.1 1.3e-09 38.2 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 CDJ50398.1 - 6.2e-08 32.5 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ50398.1 - 1.4e-07 32.0 0.0 2.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ50398.1 - 4.4e-07 30.4 0.0 8.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ50398.1 - 0.0043 16.8 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ50398.1 - 0.017 15.4 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4211 PF13926.6 CDJ50398.1 - 0.07 13.2 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) rve PF00665.26 CDJ50399.1 - 2.9e-17 63.0 0.0 1.2e-16 61.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ50399.1 - 7.4e-16 58.0 2.7 1.4e-15 57.1 2.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ50399.1 - 0.0077 16.0 0.2 2 8.2 0.1 2.4 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 CDJ50399.1 - 0.014 15.6 1.2 0.025 14.8 1.2 1.4 1 0 0 1 1 1 0 H2C2 zinc finger PepSY_TM PF03929.16 CDJ50399.1 - 0.038 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region RVT_1 PF00078.27 CDJ50399.1 - 0.039 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 CDJ50400.1 - 7e-12 45.1 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain VWA_2 PF13519.6 CDJ50402.1 - 0.57 10.9 12.3 4.3 8.0 6.1 3.7 2 1 1 3 3 3 0 von Willebrand factor type A domain AAA PF00004.29 CDJ50402.1 - 0.73 10.3 3.3 0.74 10.2 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1548 PF07579.11 CDJ50402.1 - 3.3 8.1 6.1 7.5 6.9 0.3 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) Y2_Tnp PF04986.13 CDJ50403.1 - 0.0045 17.1 0.2 0.0045 17.1 0.2 2.3 3 0 0 3 3 3 1 Putative transposase Ald_Xan_dh_C2 PF02738.18 CDJ50403.1 - 0.042 12.3 0.3 0.12 10.8 0.3 1.7 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase PKS_DE PF18369.1 CDJ50403.1 - 0.71 10.5 7.0 2 9.0 1.1 3.6 3 0 0 3 3 3 0 Polyketide synthase dimerisation element domain V_ATPase_I PF01496.19 CDJ50403.1 - 6.3 4.6 5.6 19 3.0 2.8 2.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 CDJ50406.1 - 6.2e-41 140.5 0.0 3.4e-29 102.0 0.0 5.3 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ50406.1 - 1.3e-18 67.2 0.0 2.1e-16 60.0 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ50406.1 - 1.3e-13 49.4 0.8 0.001 18.5 0.3 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ50406.1 - 7.8e-13 48.7 0.1 3.8e-05 24.1 0.0 4.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ50406.1 - 9.3e-11 40.8 3.0 0.0082 16.0 0.5 4.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CDJ50406.1 - 2.6e-07 29.8 10.5 0.18 11.4 0.4 5.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 CDJ50406.1 - 3.1e-06 26.9 4.3 0.15 11.9 0.4 5.0 4 1 1 5 5 5 2 EF-hand domain pair Presenilin PF01080.17 CDJ50406.1 - 0.0015 17.4 14.5 0.0015 17.4 14.5 7.0 7 0 0 7 7 7 2 Presenilin FYRN PF05964.14 CDJ50407.1 - 0.0086 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus Spore_YhcN_YlaJ PF09580.10 CDJ50407.1 - 1.1 9.3 0.0 1.1 9.3 0.0 18.3 10 6 4 14 14 14 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ABC_tran PF00005.27 CDJ50408.1 - 6.1e-36 124.0 33.0 3.7e-20 72.8 1.3 5.1 5 1 0 5 5 3 3 ABC transporter AAA_21 PF13304.6 CDJ50408.1 - 8.8e-26 91.4 1.7 3.6e-05 23.7 1.6 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ50408.1 - 3.5e-16 59.3 7.5 1.5e-09 37.7 0.0 3.5 3 1 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ50408.1 - 1.7e-08 34.1 0.1 0.0062 16.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 CDJ50408.1 - 1.8e-08 34.9 0.2 0.023 15.1 0.0 3.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CDJ50408.1 - 1.7e-06 28.7 1.8 0.00069 20.2 0.1 7.9 4 3 3 7 7 3 2 AAA domain MMR_HSR1 PF01926.23 CDJ50408.1 - 3.1e-06 27.2 0.3 0.063 13.4 0.0 3.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase TsaE PF02367.17 CDJ50408.1 - 4.9e-06 26.6 1.2 0.057 13.4 0.2 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CDJ50408.1 - 1.5e-05 25.6 18.2 3.1e-05 24.5 0.0 4.8 5 0 0 5 5 4 2 AAA domain RNA_helicase PF00910.22 CDJ50408.1 - 9.3e-05 22.8 1.0 0.38 11.2 0.1 2.9 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 CDJ50408.1 - 0.00014 22.1 2.5 0.00014 22.1 2.5 7.4 7 2 0 7 7 4 1 AAA domain AAA_5 PF07728.14 CDJ50408.1 - 0.00021 21.3 3.8 0.18 11.8 0.6 3.3 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CDJ50408.1 - 0.00035 20.6 0.2 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MobB PF03205.14 CDJ50408.1 - 0.0005 20.0 1.0 2.1 8.3 0.0 3.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CDJ50408.1 - 0.00057 19.8 0.6 1.3 8.9 0.0 2.7 2 0 0 2 2 2 2 NTPase AAA_14 PF13173.6 CDJ50408.1 - 0.0021 18.1 6.6 0.14 12.2 0.4 3.9 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CDJ50408.1 - 0.0026 17.5 3.9 0.0053 16.5 1.6 4.0 4 0 0 4 4 3 2 IstB-like ATP binding protein ABC_tran_Xtn PF12848.7 CDJ50408.1 - 0.0043 17.0 1.0 0.0043 17.0 1.0 10.5 7 3 1 8 8 4 1 ABC transporter AAA_33 PF13671.6 CDJ50408.1 - 0.0044 17.2 3.1 0.0044 17.2 3.1 5.9 6 2 0 6 6 4 2 AAA domain NACHT PF05729.12 CDJ50408.1 - 0.0049 16.8 3.9 0.0049 16.8 3.9 6.1 3 2 1 5 5 3 2 NACHT domain cobW PF02492.19 CDJ50408.1 - 0.006 16.2 0.0 0.046 13.3 0.0 3.4 3 0 0 3 3 2 2 CobW/HypB/UreG, nucleotide-binding domain SR-25 PF10500.9 CDJ50408.1 - 0.0067 16.1 6.6 0.0067 16.1 6.6 5.6 5 1 0 5 5 3 2 Nuclear RNA-splicing-associated protein PRK PF00485.18 CDJ50408.1 - 0.008 15.9 4.1 0.25 11.1 0.0 2.8 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.12 CDJ50408.1 - 0.0082 15.6 0.1 3.9 6.8 0.0 2.7 2 0 0 2 2 2 1 Poxvirus A32 protein Roc PF08477.13 CDJ50408.1 - 0.023 14.9 0.8 0.023 14.9 0.8 5.1 6 0 0 6 6 4 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CDJ50408.1 - 0.026 14.4 0.3 0.026 14.4 0.3 4.3 5 2 0 5 5 2 0 RsgA GTPase PduV-EutP PF10662.9 CDJ50408.1 - 0.054 13.2 10.4 0.47 10.2 0.3 3.0 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 CDJ50408.1 - 0.062 12.9 0.0 0.062 12.9 0.0 4.6 5 1 0 5 5 4 0 AAA domain AAA_24 PF13479.6 CDJ50408.1 - 0.071 12.8 0.0 0.071 12.8 0.0 4.6 5 1 1 6 6 3 0 AAA domain ATP-synt_ab PF00006.25 CDJ50408.1 - 0.081 12.6 1.3 5.3 6.6 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.18 CDJ50408.1 - 0.083 12.4 0.4 9.7 5.7 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_15 PF13175.6 CDJ50408.1 - 0.11 12.2 0.0 0.11 12.2 0.0 5.4 4 2 1 5 5 2 0 AAA ATPase domain Nucleoporin_FG2 PF15967.5 CDJ50409.1 - 6.2 5.2 19.4 7.1 5.0 19.4 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region RVT_1 PF00078.27 CDJ50410.1 - 2.7e-07 30.4 0.0 6.1e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ50411.1 - 7e-29 100.2 0.1 1.5e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ50411.1 - 7.6e-29 99.7 0.3 2.4e-28 98.1 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ50411.1 - 3.9e-13 49.6 0.2 1.3e-12 48.0 0.2 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ50411.1 - 5.3e-12 45.4 0.0 1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 CDJ50411.1 - 1.8e-10 40.8 1.4 4.4e-10 39.5 1.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CDJ50411.1 - 7.1e-06 26.5 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ50411.1 - 1.3e-05 25.7 0.0 2.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ50411.1 - 0.025 14.9 0.0 0.075 13.4 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 CDJ50411.1 - 0.053 13.7 0.4 0.13 12.5 0.4 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVP_2 PF08284.11 CDJ50411.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 CDJ50412.1 - 4.6e-11 42.7 2.1 4.6e-11 42.7 2.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain UL42 PF17638.2 CDJ50412.1 - 0.14 12.1 0.7 0.34 10.9 0.7 1.6 1 0 0 1 1 1 0 HCMV UL42 SPOUT_MTase PF02590.17 CDJ50413.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase DUF4667 PF15700.5 CDJ50415.1 - 0.01 16.0 5.5 0.01 16.0 5.5 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4667) Sec10 PF07393.11 CDJ50415.1 - 4.9 5.4 17.1 0.37 9.1 6.5 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec10 GATase PF00117.28 CDJ50417.1 - 3.3e-21 75.9 0.0 3.9e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CDJ50417.1 - 3.6e-05 23.6 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 Shadoo PF14999.6 CDJ50418.1 - 0.22 11.6 9.2 1.4 9.0 4.5 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective AP2 PF00847.20 CDJ50419.1 - 4.8e-18 65.1 4.1 7.7e-12 45.3 0.7 6.1 6 0 0 6 6 6 2 AP2 domain RskA PF10099.9 CDJ50419.1 - 0.00014 22.2 2.5 0.00014 22.2 2.5 34.1 12 10 13 27 27 27 8 Anti-sigma-K factor rskA AUX_IAA PF02309.16 CDJ50420.1 - 0.018 14.9 1.9 0.022 14.6 1.9 1.1 1 0 0 1 1 1 0 AUX/IAA family Glyco_hydro_9 PF00759.19 CDJ50420.1 - 0.29 10.5 7.2 0.39 10.1 7.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 SpoIIIAH PF12685.7 CDJ50420.1 - 1.3 8.8 8.0 1.9 8.3 8.0 1.3 1 1 0 1 1 1 0 SpoIIIAH-like protein Med3 PF11593.8 CDJ50420.1 - 4.5 6.4 11.5 5.6 6.1 11.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NST1 PF13945.6 CDJ50421.1 - 6 6.9 16.3 0.95 9.5 11.5 2.2 1 1 1 2 2 2 0 Salt tolerance down-regulator RskA PF10099.9 CDJ50423.1 - 2.4 8.4 44.2 0.16 12.3 12.9 3.5 1 1 0 2 2 2 0 Anti-sigma-K factor rskA MAP7 PF05672.11 CDJ50423.1 - 4.6 6.9 29.1 0.93 9.2 15.4 2.5 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family AAA_23 PF13476.6 CDJ50423.1 - 8.9 6.8 11.4 2 8.8 4.5 2.2 2 0 0 2 2 2 0 AAA domain DUF572 PF04502.13 CDJ50424.1 - 0.068 12.8 8.9 0.085 12.5 8.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF21 PF01595.20 CDJ50424.1 - 0.082 12.6 0.0 0.082 12.6 0.0 1.9 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain DUF4551 PF15087.6 CDJ50424.1 - 0.29 9.9 13.4 0.31 9.8 13.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC27 PF09507.10 CDJ50424.1 - 0.35 10.2 23.1 0.47 9.8 23.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Neur_chan_memb PF02932.16 CDJ50424.1 - 2.2 8.3 7.8 3.3 7.7 7.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 CDJ50424.1 - 3.7 4.5 19.1 4.5 4.3 19.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SPX PF03105.19 CDJ50424.1 - 5.1 6.9 36.3 6.9 6.5 36.3 1.1 1 0 0 1 1 1 0 SPX domain Utp14 PF04615.13 CDJ50424.1 - 6.7 5.2 18.7 8.3 4.8 18.7 1.2 1 0 0 1 1 1 0 Utp14 protein CytochromB561_N PF09786.9 CDJ50424.1 - 7.1 5.5 25.5 8.4 5.3 25.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal MAP17 PF15807.5 CDJ50426.1 - 0.00039 20.6 1.1 0.00039 20.6 1.1 2.0 2 0 0 2 2 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TFIIA PF03153.13 CDJ50426.1 - 0.00096 19.3 24.8 0.001 19.1 24.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2232 PF09991.9 CDJ50426.1 - 0.0071 15.6 8.4 0.0095 15.1 8.4 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) Connexin PF00029.19 CDJ50426.1 - 0.0079 16.0 2.6 0.011 15.5 2.6 1.2 1 0 0 1 1 1 1 Connexin DDHD PF02862.17 CDJ50426.1 - 0.012 15.8 1.6 0.012 15.8 1.6 1.1 1 0 0 1 1 1 0 DDHD domain O-antigen_lig PF13425.6 CDJ50426.1 - 0.014 14.2 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CDC45 PF02724.14 CDJ50426.1 - 0.018 13.4 2.0 0.018 13.4 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 CDJ50426.1 - 0.021 15.0 4.7 0.032 14.4 4.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF1980 PF09323.10 CDJ50426.1 - 0.031 14.2 0.2 0.038 13.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) FAM176 PF14851.6 CDJ50426.1 - 0.04 13.6 2.2 0.08 12.6 2.2 1.5 1 0 0 1 1 1 0 FAM176 family YfhO PF09586.10 CDJ50426.1 - 0.042 12.1 0.7 0.049 11.9 0.7 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SpoIIP PF07454.11 CDJ50426.1 - 0.044 13.2 5.2 0.052 13.0 5.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 CDJ50426.1 - 0.048 13.7 6.9 0.067 13.3 6.9 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein eIF-3_zeta PF05091.12 CDJ50426.1 - 0.057 12.4 10.9 0.065 12.2 10.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ50426.1 - 0.08 13.0 9.2 0.097 12.7 9.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ50426.1 - 0.094 12.3 30.0 0.11 12.0 30.0 1.1 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ50426.1 - 0.12 12.4 12.3 0.14 12.1 12.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) V_ATPase_I PF01496.19 CDJ50426.1 - 0.15 10.0 4.5 0.18 9.7 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family G0-G1_switch_2 PF15103.6 CDJ50426.1 - 0.15 12.5 6.2 0.27 11.7 6.2 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF702 PF05142.12 CDJ50426.1 - 0.2 12.1 7.8 0.35 11.3 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) TFB6 PF17110.5 CDJ50426.1 - 0.25 11.1 4.2 0.33 10.7 4.2 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DXP_synthase_N PF13292.6 CDJ50426.1 - 0.25 10.5 7.3 0.29 10.3 7.3 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Band_3_cyto PF07565.13 CDJ50426.1 - 0.32 10.8 4.3 0.38 10.5 4.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FHIPEP PF00771.20 CDJ50426.1 - 0.33 9.4 13.4 0.4 9.1 13.4 1.1 1 0 0 1 1 1 0 FHIPEP family DUF3408 PF11888.8 CDJ50426.1 - 0.51 10.5 8.1 0.72 10.0 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) RR_TM4-6 PF06459.12 CDJ50426.1 - 0.68 9.7 7.3 0.81 9.5 7.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2722 PF10846.8 CDJ50426.1 - 0.71 8.8 27.5 0.93 8.4 27.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) API5 PF05918.11 CDJ50426.1 - 0.82 8.4 8.6 0.96 8.2 8.6 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF4834 PF16118.5 CDJ50426.1 - 0.84 10.6 15.5 1.5 9.8 15.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) AXIN1_TNKS_BD PF16646.5 CDJ50426.1 - 0.89 10.5 5.6 1.6 9.7 5.6 1.4 1 0 0 1 1 1 0 Axin-1 tankyrase binding domain Coilin_N PF15862.5 CDJ50426.1 - 0.95 9.3 9.3 1.3 8.8 9.3 1.1 1 0 0 1 1 1 0 Coilin N-terminus Paf1 PF03985.13 CDJ50426.1 - 1.5 7.8 10.6 1.8 7.5 10.6 1.0 1 0 0 1 1 1 0 Paf1 PAT1 PF09770.9 CDJ50426.1 - 1.7 6.8 16.0 2 6.6 16.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4770 PF15994.5 CDJ50426.1 - 1.9 8.7 10.7 2.5 8.3 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Sporozoite_P67 PF05642.11 CDJ50426.1 - 3.5 5.6 13.7 4.9 5.1 13.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hid1 PF12722.7 CDJ50426.1 - 3.7 5.6 6.6 4.2 5.4 6.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TMEM208_SND2 PF05620.11 CDJ50426.1 - 6.3 6.6 10.5 2.9 7.6 8.1 1.7 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 UPF0560 PF10577.9 CDJ50426.1 - 6.3 5.2 15.2 7.8 4.9 15.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Serinc PF03348.15 CDJ50426.1 - 9.7 5.0 9.9 12 4.7 9.9 1.3 1 1 0 1 1 1 0 Serine incorporator (Serinc) RAP1 PF07218.11 CDJ50427.1 - 0.49 8.6 11.0 0.71 8.1 11.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) U1snRNP70_N PF12220.8 CDJ50427.1 - 4.4 8.0 12.5 3.1 8.5 0.2 3.2 4 0 0 4 4 4 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TFIIA PF03153.13 CDJ50427.1 - 8.5 6.2 40.8 19 5.1 40.8 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNF PF00209.18 CDJ50428.1 - 4.3e-27 95.0 11.2 2.2e-26 92.7 11.2 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family SARAF PF06682.12 CDJ50428.1 - 0.00028 20.6 14.0 0.00028 20.6 14.0 5.1 5 0 0 5 5 5 2 SOCE-associated regulatory factor of calcium homoeostasis eIF-3_zeta PF05091.12 CDJ50428.1 - 3.2 6.6 10.4 7.4 5.4 10.4 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PH PF00169.29 CDJ50429.1 - 1.2e-06 29.0 0.0 6.3e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 PH domain Ndc1_Nup PF09531.10 CDJ50429.1 - 0.00016 20.5 4.5 0.00017 20.5 4.5 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ50429.1 - 0.037 12.8 8.6 0.05 12.4 8.6 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 CDJ50429.1 - 0.038 12.5 8.5 0.069 11.7 8.5 1.4 1 0 0 1 1 1 0 Macoilin family DUF2828 PF11443.8 CDJ50429.1 - 0.051 11.7 5.6 0.069 11.2 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TFB6 PF17110.5 CDJ50429.1 - 0.19 11.5 4.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH PI3K_1B_p101 PF10486.9 CDJ50429.1 - 0.64 7.7 12.8 0.85 7.3 12.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Peroxin-3 PF04882.12 CDJ50429.1 - 1.7 7.6 15.7 2.8 6.8 15.7 1.3 1 0 0 1 1 1 0 Peroxin-3 Med15 PF09606.10 CDJ50429.1 - 2.1 7.0 26.1 13 4.3 27.2 1.8 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal GREB1 PF15782.5 CDJ50429.1 - 5.7 3.9 14.0 7.9 3.5 14.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 CDJ50429.1 - 6.4 5.7 13.8 9.3 5.1 13.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SPX PF03105.19 CDJ50429.1 - 6.7 6.5 16.8 10 5.9 16.8 1.2 1 0 0 1 1 1 0 SPX domain PPP4R2 PF09184.11 CDJ50429.1 - 7.6 6.0 10.3 11 5.5 10.3 1.2 1 0 0 1 1 1 0 PPP4R2 SR-25 PF10500.9 CDJ50429.1 - 8.7 5.9 27.5 28 4.2 27.4 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ50431.1 - 5.8e-05 22.2 2.4 5.8e-05 22.2 2.4 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ50432.1 - 9.5e-07 29.3 77.4 0.018 15.4 5.0 5.4 3 2 2 5 5 5 5 Anti-sigma-K factor rskA DUF2681 PF10883.8 CDJ50432.1 - 0.026 14.9 3.3 0.026 14.9 3.3 4.4 4 1 0 4 4 4 0 Protein of unknown function (DUF2681) DUF2828 PF11443.8 CDJ50432.1 - 0.41 8.7 5.7 0.058 11.5 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) eIF3_p135 PF12807.7 CDJ50432.1 - 1.4 8.9 9.9 0.24 11.4 0.2 2.6 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit 135 Band_3_cyto PF07565.13 CDJ50432.1 - 2.6 7.8 16.2 2.5 7.9 1.3 3.2 3 0 0 3 3 3 0 Band 3 cytoplasmic domain DUF2722 PF10846.8 CDJ50432.1 - 3.6 6.4 59.2 0.43 9.5 11.8 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) cwf18 PF08315.12 CDJ50432.1 - 4.7 7.9 17.8 0.96 10.1 0.3 3.4 3 0 0 3 3 3 0 cwf18 pre-mRNA splicing factor Rxt3 PF08642.10 CDJ50432.1 - 5.9 7.7 11.2 21 5.9 0.2 3.3 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 OATP PF03137.20 CDJ50432.1 - 6.7 4.9 11.6 2.1 6.6 0.3 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.13 CDJ50432.1 - 7.3 6.5 75.0 0.055 13.5 14.3 3.1 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 CDJ50433.1 - 2.7 6.2 3.5 2.4 6.3 3.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF5441 PF17513.2 CDJ50434.1 - 0.0082 15.9 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5441) DRMBL PF07522.14 CDJ50434.1 - 0.028 14.6 3.6 0.11 12.6 3.6 2.1 1 1 0 1 1 1 0 DNA repair metallo-beta-lactamase SurA_N_2 PF13623.6 CDJ50435.1 - 0.017 15.0 11.9 0.018 14.9 11.9 1.1 1 0 0 1 1 1 0 SurA N-terminal domain Spt20 PF12090.8 CDJ50435.1 - 0.036 13.7 24.7 0.039 13.6 24.7 1.0 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ50435.1 - 0.094 13.7 7.3 0.11 13.5 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CTU2 PF10288.9 CDJ50435.1 - 0.23 11.7 12.3 0.27 11.5 12.3 1.0 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Fe_bilin_red PF05996.12 CDJ50435.1 - 0.41 10.3 10.2 0.45 10.2 10.2 1.0 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase eIF-3_zeta PF05091.12 CDJ50435.1 - 1.1 8.1 11.3 1.2 8.1 11.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3464 PF11947.8 CDJ50435.1 - 1.2 8.8 5.9 1.4 8.7 5.9 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 EOS1 PF12326.8 CDJ50435.1 - 1.4 8.8 4.1 1.5 8.7 4.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein TFIIA PF03153.13 CDJ50435.1 - 1.6 8.7 22.2 1.7 8.6 22.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ50435.1 - 2.3 6.9 7.5 2.5 6.8 7.5 1.1 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 CDJ50435.1 - 3.1 6.2 13.0 3 6.2 13.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Androgen_recep PF02166.16 CDJ50435.1 - 3.8 6.2 21.3 3.5 6.4 21.3 1.1 1 0 0 1 1 1 0 Androgen receptor Cellulose_synt PF03552.14 CDJ50435.1 - 4 5.8 4.8 4.2 5.7 4.8 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF2722 PF10846.8 CDJ50435.1 - 5.7 5.8 24.7 5.8 5.8 24.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ50435.1 - 5.9 6.8 13.6 6.6 6.6 13.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4175 PF13779.6 CDJ50435.1 - 7.5 4.3 19.1 7.8 4.3 19.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DivIC PF04977.15 CDJ50435.1 - 7.8 6.3 15.4 11 5.9 15.4 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF4010 PF13194.6 CDJ50436.1 - 0.0012 18.6 0.2 0.0015 18.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) SR-25 PF10500.9 CDJ50436.1 - 9.3 5.8 18.1 15 5.1 18.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2574 PF10836.8 CDJ50437.1 - 1.3 8.9 9.1 4.8 7.1 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2574) Cwf_Cwc_15 PF04889.12 CDJ50439.1 - 0.0053 16.5 17.1 0.0053 16.5 17.1 4.2 3 1 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein Hamartin PF04388.12 CDJ50439.1 - 3.9 6.0 60.0 0.062 12.0 21.7 2.2 2 0 0 2 2 2 0 Hamartin protein SR-25 PF10500.9 CDJ50441.1 - 0.00017 21.3 36.7 0.00025 20.7 16.3 14.0 7 3 4 11 11 11 3 Nuclear RNA-splicing-associated protein HC2 PF07382.11 CDJ50442.1 - 0.0036 17.4 19.9 0.0045 17.1 19.9 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Peptidase_M99_C PF17129.4 CDJ50442.1 - 2.1 8.6 7.3 67 3.8 5.9 2.8 1 1 0 1 1 1 0 C-terminal domain of metallo-carboxypeptidase Rrn6 PF10214.9 CDJ50443.1 - 0.22 10.0 13.5 0.27 9.7 13.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Helicase_RecD PF05127.14 CDJ50444.1 - 0.013 15.4 4.9 0.015 15.1 4.9 1.0 1 0 0 1 1 1 0 Helicase PTPRCAP PF15713.5 CDJ50444.1 - 0.14 12.4 13.3 0.19 12.0 13.3 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PsbW PF07123.12 CDJ50444.1 - 0.31 11.0 4.3 0.46 10.5 4.3 1.4 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) TFIIA PF03153.13 CDJ50444.1 - 0.55 10.2 31.1 0.63 10.0 31.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ50444.1 - 0.57 10.8 19.0 0.72 10.5 19.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.12 CDJ50444.1 - 0.62 9.0 13.1 0.63 8.9 13.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 CDJ50444.1 - 0.76 9.9 11.4 0.99 9.6 11.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4746 PF15928.5 CDJ50444.1 - 0.77 9.1 9.3 0.81 9.1 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NARP1 PF12569.8 CDJ50444.1 - 0.88 8.4 15.8 0.98 8.2 15.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CbiD PF01888.17 CDJ50444.1 - 1.3 8.2 7.7 0.58 9.4 0.8 2.0 2 0 0 2 2 2 0 CbiD DUF3807 PF12720.7 CDJ50444.1 - 1.4 9.1 17.4 1.8 8.8 17.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SRP-alpha_N PF04086.13 CDJ50444.1 - 1.5 8.7 13.6 1.8 8.5 13.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Asp-B-Hydro_N PF05279.11 CDJ50444.1 - 1.8 8.6 11.5 2 8.4 11.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region UPF0239 PF06783.11 CDJ50444.1 - 1.8 8.8 12.3 1.3 9.3 8.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) OATP PF03137.20 CDJ50444.1 - 2.1 6.5 6.0 2.5 6.3 6.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Sec62 PF03839.16 CDJ50444.1 - 2.2 7.7 9.9 2.3 7.7 9.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Membralin PF09746.9 CDJ50444.1 - 2.7 6.9 5.3 2.9 6.9 5.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein Connexin PF00029.19 CDJ50444.1 - 2.8 7.6 7.8 3.1 7.5 7.8 1.2 1 0 0 1 1 1 0 Connexin FemAB PF02388.16 CDJ50444.1 - 3.9 6.2 13.5 4.5 6.0 13.5 1.0 1 0 0 1 1 1 0 FemAB family DUF913 PF06025.12 CDJ50444.1 - 3.9 6.3 9.4 4.6 6.1 9.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Fic PF02661.18 CDJ50444.1 - 4.3 8.3 5.6 4.3 8.3 4.6 1.5 1 1 0 1 1 1 0 Fic/DOC family LAP1C PF05609.12 CDJ50444.1 - 4.3 6.3 18.4 4.4 6.3 18.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2052 PF09747.9 CDJ50444.1 - 4.6 7.3 14.7 5.3 7.1 14.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RuvC_III PF18541.1 CDJ50444.1 - 5 7.0 10.5 6.3 6.7 10.5 1.2 1 0 0 1 1 1 0 RuvC endonuclease subdomain 3 CDC45 PF02724.14 CDJ50444.1 - 6 5.0 12.7 5.8 5.1 12.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 CDJ50444.1 - 6.9 5.3 12.7 8.4 5.1 12.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 CDJ50444.1 - 7.2 6.4 17.9 8 6.2 17.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.9 CDJ50444.1 - 7.7 6.6 10.4 8.5 6.4 10.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Baculo_PP31 PF05311.11 CDJ50444.1 - 8 5.9 11.2 9.9 5.6 11.2 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DDRGK PF09756.9 CDJ50444.1 - 8.2 6.0 18.1 9.8 5.7 18.1 1.1 1 0 0 1 1 1 0 DDRGK domain Presenilin PF01080.17 CDJ50444.1 - 8.3 5.1 17.1 8.9 5.0 17.1 1.0 1 0 0 1 1 1 0 Presenilin Ctr PF04145.15 CDJ50444.1 - 8.8 6.9 7.2 11 6.7 7.2 1.3 1 0 0 1 1 1 0 Ctr copper transporter family ALMT PF11744.8 CDJ50444.1 - 8.9 5.0 9.1 9.4 4.9 9.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 CDJ50444.1 - 9.4 6.2 13.7 10 6.1 13.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ50444.1 - 9.6 5.9 12.2 10 5.8 12.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SR-25 PF10500.9 CDJ50445.1 - 7.9e-11 42.0 31.6 2.8e-07 30.4 17.9 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 CDJ50445.1 - 0.013 13.8 22.3 0.0075 14.6 8.9 2.1 2 0 0 2 2 2 0 CDC45-like protein ANAPC_CDC26 PF10471.9 CDJ50445.1 - 0.018 15.9 16.5 0.018 15.9 16.5 3.9 3 1 1 4 4 2 0 Anaphase-promoting complex APC subunit CDC26 DUF3408 PF11888.8 CDJ50445.1 - 0.022 14.9 18.2 0.19 11.9 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) TCP PF03634.13 CDJ50445.1 - 0.024 15.2 32.1 0.3 11.6 6.3 2.4 2 0 0 2 2 2 0 TCP family transcription factor IMUP PF15761.5 CDJ50445.1 - 0.041 14.6 3.3 0.041 14.6 3.3 4.0 1 1 3 4 4 4 0 Immortalisation up-regulated protein eIF-3_zeta PF05091.12 CDJ50445.1 - 0.12 11.4 26.5 0.45 9.4 12.7 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Endostatin PF06482.11 CDJ50445.1 - 0.27 10.7 23.0 0.59 9.6 12.7 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Activator_LAG-3 PF11498.8 CDJ50445.1 - 1.1 8.1 64.2 0.027 13.5 18.9 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Suf PF05843.14 CDJ50445.1 - 2.2 8.2 30.2 1.9 8.4 16.3 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FAM60A PF15396.6 CDJ50445.1 - 2.6 8.0 23.1 1.9 8.5 11.2 2.2 2 0 0 2 2 2 0 Protein Family FAM60A SLC12 PF03522.15 CDJ50445.1 - 3.9 6.4 22.7 2.8 6.8 12.2 2.0 2 0 0 2 2 2 0 Solute carrier family 12 DUF3807 PF12720.7 CDJ50445.1 - 4.4 7.5 30.7 4.2 7.6 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Presenilin PF01080.17 CDJ50445.1 - 5.7 5.6 33.8 2.3 6.9 18.3 2.1 2 0 0 2 2 2 0 Presenilin SMYLE_N PF18615.1 CDJ50445.1 - 5.7 6.4 28.4 4.6 6.7 13.7 2.1 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Dsh_C PF12316.8 CDJ50445.1 - 7.6 6.9 39.0 5.7 7.3 19.1 2.1 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal EOS1 PF12326.8 CDJ50445.1 - 8.9 6.2 19.2 9.6 6.1 4.0 2.3 2 0 0 2 2 2 0 N-glycosylation protein Patched PF02460.18 CDJ50446.1 - 1.6e-89 301.1 21.5 2.3e-55 188.1 0.0 2.9 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDJ50446.1 - 1.3e-29 103.0 7.1 1.3e-29 103.0 7.1 2.2 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation IZUMO PF15005.6 CDJ50446.1 - 1.4 9.4 4.0 0.8 10.2 0.1 2.5 3 1 1 4 4 4 0 Izumo sperm-egg fusion, Ig domain-associated MORN PF02493.20 CDJ50447.1 - 5.4e-20 70.0 26.9 0.00011 21.9 0.5 5.7 6 0 0 6 6 6 5 MORN repeat Stress-antifung PF01657.17 CDJ50447.1 - 0.52 11.0 2.6 5.7 7.6 0.2 3.0 2 0 0 2 2 2 0 Salt stress response/antifungal CRAL_TRIO PF00650.20 CDJ50448.1 - 0.00085 19.1 0.0 0.0022 17.7 0.0 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ50448.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain MoaF PF10703.9 CDJ50448.1 - 0.18 11.8 1.7 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 MoaF N-terminal domain FSA_C PF10479.9 CDJ50448.1 - 0.53 8.4 2.5 0.71 7.9 2.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF2057 PF09829.9 CDJ50448.1 - 3.1 7.9 9.2 5.8 7.0 9.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) HAGH_C PF16123.5 CDJ50449.1 - 4.4e-27 94.4 0.0 9.8e-27 93.3 0.0 1.6 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CDJ50449.1 - 3.3e-08 33.8 0.3 6.8e-08 32.8 0.3 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ50449.1 - 0.092 12.2 1.6 0.23 11.0 0.0 2.3 2 1 0 2 2 2 0 Beta-lactamase superfamily domain RskA PF10099.9 CDJ50449.1 - 2.7 8.3 26.0 5.7 7.2 26.0 1.6 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Mito_carr PF00153.27 CDJ50450.1 - 1.1e-33 115.0 8.4 9.7e-16 57.5 1.1 3.9 2 2 0 2 2 2 2 Mitochondrial carrier protein SARAF PF06682.12 CDJ50450.1 - 7.6e-05 22.5 13.6 7.6e-05 22.5 13.6 2.7 2 1 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis RNA_pol_I_A49 PF06870.12 CDJ50450.1 - 0.049 12.5 2.3 0.1 11.4 2.3 1.4 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor HCV_NS5a_1a PF08300.13 CDJ50450.1 - 0.081 13.1 0.3 15 5.8 0.0 2.3 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain Menin PF05053.13 CDJ50450.1 - 1.4 7.2 9.0 0.11 10.8 2.5 2.1 2 0 0 2 2 2 0 Menin Apt1 PF10351.9 CDJ50450.1 - 5.9 5.6 21.1 3.3 6.5 10.8 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Peptidase_C33 PF05412.12 CDJ50452.1 - 0.09 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase Spt20 PF12090.8 CDJ50452.1 - 0.83 9.2 8.1 0.97 9.0 8.1 1.1 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ50452.1 - 2.2 7.8 8.4 2.9 7.4 8.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCCH_3 PF15663.5 CDJ50454.1 - 1.7e-06 28.2 6.2 0.0024 18.1 1.0 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH PF00642.24 CDJ50454.1 - 2.6e-05 24.0 14.3 5.2e-05 23.0 1.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ50454.1 - 0.00089 19.0 17.4 0.029 14.2 5.7 2.8 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CDJ50454.1 - 0.028 14.9 1.3 0.028 14.9 1.3 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CDJ50454.1 - 0.034 14.8 11.5 0.46 11.2 4.3 2.6 1 1 1 2 2 2 0 Torus domain Pex19 PF04614.12 CDJ50454.1 - 5.5 6.7 6.1 0.5 10.1 0.7 1.9 2 0 0 2 2 2 0 Pex19 protein family GET2 PF08690.10 CDJ50455.1 - 0.14 11.9 7.3 0.2 11.3 7.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIA PF03153.13 CDJ50455.1 - 0.16 11.9 30.9 0.27 11.2 30.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ50455.1 - 0.32 10.8 7.7 0.44 10.3 7.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.13 CDJ50455.1 - 0.67 9.7 7.2 1 9.1 7.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SKA1 PF07160.12 CDJ50455.1 - 1.1 9.0 8.5 1.6 8.5 8.5 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 MRP-S31 PF15433.6 CDJ50455.1 - 1.4 8.5 7.6 2 8.0 7.6 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 eIF-3_zeta PF05091.12 CDJ50455.1 - 1.6 7.6 10.9 2.1 7.2 10.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ50455.1 - 1.7 6.9 17.3 1.8 6.7 17.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PBP_sp32 PF07222.12 CDJ50455.1 - 5.6 6.3 15.4 0.04 13.4 2.0 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 DUF5327 PF17261.2 CDJ50455.1 - 9 7.1 13.9 15 6.4 3.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) NST1 PF13945.6 CDJ50455.1 - 9 6.4 15.3 0.89 9.6 5.6 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator TPR_MLP1_2 PF07926.12 CDJ50456.1 - 0.00043 20.3 27.8 0.00043 20.3 27.8 10.4 3 3 5 9 9 9 2 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 CDJ50456.1 - 0.0081 16.2 4.0 0.0081 16.2 4.0 10.1 5 3 6 12 12 12 4 Protein of unknown function (DUF1664) EPL1 PF10513.9 CDJ50457.1 - 2.1 8.7 7.3 0.81 10.1 0.9 2.7 3 0 0 3 3 3 0 Enhancer of polycomb-like Presenilin PF01080.17 CDJ50457.1 - 9.5 4.9 16.7 2.1 7.0 2.8 3.1 2 1 0 2 2 2 0 Presenilin Membralin PF09746.9 CDJ50458.1 - 4.6 6.2 7.4 6.9 5.6 7.4 1.3 1 0 0 1 1 1 0 Tumour-associated protein LMBR1 PF04791.16 CDJ50458.1 - 9.9 4.9 7.9 17 4.2 7.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 CDJ50459.1 - 0.0011 18.6 9.4 0.012 15.2 9.1 2.1 1 1 1 2 2 2 1 Exonuclease VII, large subunit SAPS PF04499.15 CDJ50459.1 - 0.053 12.3 7.9 0.077 11.8 7.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAP2 PF01569.21 CDJ50459.1 - 0.32 10.8 1.5 0.51 10.1 0.1 2.0 2 0 0 2 2 2 0 PAP2 superfamily Zip PF02535.22 CDJ50459.1 - 0.43 9.7 8.8 1.3 8.2 7.2 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Lin-8 PF03353.15 CDJ50459.1 - 0.53 9.8 29.0 0.12 11.9 22.9 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CCSAP PF15748.5 CDJ50459.1 - 0.77 9.9 29.8 0.1 12.8 21.9 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 CDJ50459.1 - 2.6 6.3 19.3 4.4 5.5 19.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF5427 PF10310.9 CDJ50459.1 - 6.8 5.5 28.7 0.15 10.9 20.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Ribosomal_60s PF00428.19 CDJ50460.1 - 2.6 8.7 13.0 0.78 10.4 9.9 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein RAP1 PF07218.11 CDJ50460.1 - 4.1 5.6 11.7 4.5 5.4 11.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SelB-wing_3 PF09107.11 CDJ50461.1 - 0.032 13.9 0.6 1.2 8.8 0.2 2.3 2 0 0 2 2 2 0 Elongation factor SelB, winged helix SPX PF03105.19 CDJ50461.1 - 0.11 12.4 15.1 0.13 12.1 15.1 1.1 1 0 0 1 1 1 0 SPX domain DUF572 PF04502.13 CDJ50461.1 - 1.6 8.3 13.1 1.8 8.1 13.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1764 PF08576.10 CDJ50461.1 - 1.9 9.4 10.1 0.3 12.0 2.3 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF2722 PF10846.8 CDJ50462.1 - 0.00028 20.0 22.1 0.0055 15.7 16.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Pkinase PF00069.25 CDJ50463.1 - 5.3e-07 29.3 0.0 5.3e-07 29.3 0.0 3.3 3 0 0 3 3 3 1 Protein kinase domain SUIM_assoc PF16619.5 CDJ50465.1 - 2 8.5 8.8 0.4 10.8 4.6 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Apt1 PF10351.9 CDJ50466.1 - 0.023 13.5 5.5 0.028 13.3 5.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mitofilin PF09731.9 CDJ50466.1 - 0.43 9.3 21.6 0.47 9.2 21.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Paf1 PF03985.13 CDJ50466.1 - 0.57 9.1 11.0 0.63 9.0 11.0 1.3 1 0 0 1 1 1 0 Paf1 BAF1_ABF1 PF04684.13 CDJ50466.1 - 2.3 7.1 16.0 2.6 7.0 16.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4407 PF14362.6 CDJ50466.1 - 2.8 7.2 17.9 3.2 7.0 17.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peroxin-13_N PF04088.13 CDJ50466.1 - 3.1 8.0 5.5 1 9.7 2.5 1.7 1 1 1 2 2 2 0 Peroxin 13, N-terminal region DUF4834 PF16118.5 CDJ50466.1 - 3.9 8.5 13.5 13 6.8 13.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Gti1_Pac2 PF09729.9 CDJ50466.1 - 4.6 7.3 9.3 6.7 6.8 9.3 1.3 1 1 0 1 1 1 0 Gti1/Pac2 family TFIIA PF03153.13 CDJ50466.1 - 4.7 7.1 25.0 6.9 6.5 25.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 CDJ50466.1 - 8.6 5.1 6.1 9.6 4.9 6.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter TERB2 PF15101.6 CDJ50466.1 - 8.7 6.3 13.6 11 6.0 13.6 1.4 1 1 0 1 1 1 0 Telomere-associated protein TERB2 BAF1_ABF1 PF04684.13 CDJ50467.1 - 0.25 10.3 27.3 0.27 10.2 27.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RskA PF10099.9 CDJ50467.1 - 1.9 8.8 32.1 2.8 8.2 32.0 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Sulf_transp PF04143.14 CDJ50467.1 - 4.8 6.6 4.5 5 6.6 4.5 1.0 1 0 0 1 1 1 0 Sulphur transport Rhodanese PF00581.20 CDJ50468.1 - 0.011 16.2 0.0 8 7.0 0.0 3.2 2 0 0 2 2 2 0 Rhodanese-like domain PsbH PF00737.20 CDJ50468.1 - 0.025 14.3 0.5 0.069 12.9 0.1 1.8 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein SDA1 PF05285.12 CDJ50468.1 - 1.9 7.9 27.5 0.27 10.6 19.9 2.1 2 0 0 2 2 2 0 SDA1 SOBP PF15279.6 CDJ50468.1 - 7.4 7.1 44.0 3.6 8.1 27.6 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein zf-CCCH PF00642.24 CDJ50469.1 - 9.4e-11 41.4 13.7 1.9e-05 24.4 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ50469.1 - 4e-05 23.5 15.9 0.011 15.8 5.7 2.6 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 CDJ50469.1 - 6.6e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 CDJ50469.1 - 0.00032 21.4 4.3 0.15 12.8 0.8 2.5 2 1 0 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 CDJ50469.1 - 0.029 14.6 3.0 2.6 8.3 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 CDJ50469.1 - 1.3 8.9 16.2 3 7.8 6.6 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger SR-25 PF10500.9 CDJ50473.1 - 1.2e-05 25.1 4.0 1.2e-05 25.1 4.0 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein FAM117 PF15388.6 CDJ50473.1 - 0.00099 18.6 1.6 0.0013 18.2 1.6 1.2 1 0 0 1 1 1 1 Protein Family FAM117 Cwf_Cwc_15 PF04889.12 CDJ50473.1 - 0.016 14.9 5.9 0.031 14.0 0.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Lin-8 PF03353.15 CDJ50473.1 - 0.019 14.5 0.7 0.019 14.5 0.7 1.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist ANAPC1 PF12859.7 CDJ50473.1 - 0.023 15.3 1.5 0.93 10.1 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Calpain_inhib PF00748.19 CDJ50473.1 - 0.034 14.6 4.9 0.054 14.0 4.9 1.3 1 0 0 1 1 1 0 Calpain inhibitor YliH PF10799.8 CDJ50473.1 - 0.041 13.8 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) YgaB PF14182.6 CDJ50473.1 - 0.098 13.1 3.2 0.25 11.8 0.5 2.2 2 0 0 2 2 2 0 YgaB-like protein RAP1 PF07218.11 CDJ50473.1 - 0.12 10.7 2.2 0.12 10.7 2.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_pp85 PF04637.12 CDJ50473.1 - 2.1 6.7 4.0 2.7 6.3 4.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) IATP PF04568.12 CDJ50474.1 - 0.013 15.9 3.3 0.04 14.3 3.3 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP ADP_ribosyl_GH PF03747.14 CDJ50474.1 - 0.085 12.6 8.8 0.1 12.3 8.8 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Exonuc_VII_L PF02601.15 CDJ50474.1 - 0.2 11.2 9.8 0.34 10.5 9.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM199X PF15814.5 CDJ50474.1 - 0.27 10.2 5.1 0.37 9.8 5.1 1.3 1 0 0 1 1 1 0 Protein family FAM199X eIF2A PF08662.11 CDJ50475.1 - 2.3e-08 34.1 1.2 4.6e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A GRIM-19 PF06212.12 CDJ50475.1 - 0.13 12.2 2.7 0.23 11.4 2.7 1.5 1 0 0 1 1 1 0 GRIM-19 protein EMC3_TMCO1 PF01956.16 CDJ50475.1 - 0.28 10.9 1.1 0.37 10.5 1.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like eIF2A PF08662.11 CDJ50477.1 - 8.5e-09 35.6 0.1 9.6e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CDJ50477.1 - 3.8e-05 23.4 0.0 8.9e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cullin PF00888.22 CDJ50478.1 - 3.5e-22 78.8 31.9 1e-18 67.4 18.6 5.2 5 1 0 5 5 5 3 Cullin family Cullin_Nedd8 PF10557.9 CDJ50478.1 - 1.2e-07 31.6 0.0 4.3e-07 29.9 0.0 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF1645 PF07816.11 CDJ50478.1 - 0.00031 21.4 5.9 0.00031 21.4 5.9 13.5 8 5 2 10 10 10 1 Protein of unknown function (DUF1645) Activator_LAG-3 PF11498.8 CDJ50478.1 - 0.0017 17.5 21.1 0.0017 17.5 21.1 11.1 9 3 2 11 11 11 1 Transcriptional activator LAG-3 RskA PF10099.9 CDJ50479.1 - 0.046 14.0 9.2 0.083 13.2 9.2 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ50479.1 - 2.1 9.0 8.7 7.5 7.2 8.7 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pro_isomerase PF00160.21 CDJ50483.1 - 1.3e-41 142.5 0.0 1.5e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Kinase-like PF14531.6 CDJ50484.1 - 7e-07 28.8 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 CDJ50484.1 - 3.1e-05 23.5 0.0 6.4e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ50484.1 - 0.00015 21.2 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ50485.1 - 1.5e-08 34.3 0.0 3.1e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ50485.1 - 4.2e-05 23.0 0.0 6.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ50485.1 - 0.00035 20.0 0.0 0.00048 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CDJ50486.1 - 1.4e-17 63.9 0.0 3e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ50486.1 - 8.1e-06 25.3 0.0 2.8e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ50486.1 - 9.9e-05 21.8 0.0 0.0012 18.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.25 CDJ50487.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain GDYXXLXY PF14345.6 CDJ50487.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 GDYXXLXY protein TFIIA PF03153.13 CDJ50488.1 - 0.44 10.5 14.4 0.58 10.1 14.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RPOL_N PF14700.6 CDJ50489.1 - 1.6 8.1 42.5 1.8 7.9 7.9 3.1 3 0 0 3 3 3 0 DNA-directed RNA polymerase N-terminal DUF2722 PF10846.8 CDJ50490.1 - 0.014 14.4 0.2 0.014 14.4 0.2 6.8 6 1 1 7 7 7 0 Protein of unknown function (DUF2722) Peroxin-3 PF04882.12 CDJ50490.1 - 2.6 7.0 0.0 2.6 7.0 0.0 5.3 4 2 1 5 5 5 0 Peroxin-3 Ras PF00071.22 CDJ50491.1 - 3.4e-08 33.3 0.1 5.4e-08 32.6 0.0 1.5 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CDJ50491.1 - 0.0048 17.1 0.1 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF4045 PF13254.6 CDJ50491.1 - 0.3 10.7 4.0 0.32 10.6 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Nop14 PF04147.12 CDJ50491.1 - 0.58 8.3 25.8 0.67 8.1 25.8 1.0 1 0 0 1 1 1 0 Nop14-like family SLC12 PF03522.15 CDJ50491.1 - 1.8 7.5 7.3 2.1 7.3 7.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 TP53IP5 PF15331.6 CDJ50491.1 - 4.9 7.2 5.8 7.5 6.6 5.8 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Hid1 PF12722.7 CDJ50491.1 - 6.1 4.8 10.7 7.2 4.6 10.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 CDJ50491.1 - 8.8 5.0 14.7 10 4.7 14.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF5479 PF17575.2 CDJ50492.1 - 0.09 13.3 5.3 0.16 12.5 5.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5479) V_ATPase_I PF01496.19 CDJ50493.1 - 5.8 4.7 26.1 8.6 4.1 26.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSP70 PF00012.20 CDJ50493.1 - 9.1 4.3 20.1 11 4.0 20.1 1.0 1 0 0 1 1 1 0 Hsp70 protein RNA_pol_Rpb2_4 PF04566.13 CDJ50494.1 - 3.5 8.0 4.2 3.4 8.0 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 Ribosomal_L37 PF08561.10 CDJ50495.1 - 0.11 13.0 0.0 1.2 9.7 0.0 2.4 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L37 Sporozoite_P67 PF05642.11 CDJ50495.1 - 0.12 10.4 1.5 0.17 10.0 1.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen 5-nucleotidase PF06189.12 CDJ50495.1 - 0.4 9.6 1.2 0.87 8.5 0.1 1.9 2 0 0 2 2 2 0 5'-nucleotidase DUF2722 PF10846.8 CDJ50496.1 - 0.0006 18.9 8.7 0.0006 18.9 8.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) OppC_N PF12911.7 CDJ50496.1 - 0.034 14.1 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C RAB3GAP2_N PF14655.6 CDJ50496.1 - 0.069 12.4 5.9 0.13 11.5 5.9 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CAF1 PF04857.20 CDJ50496.1 - 0.15 11.2 0.3 0.21 10.7 0.3 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease RLL PF10036.9 CDJ50496.1 - 0.4 10.5 11.3 1.2 8.9 2.6 2.4 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein DUF1980 PF09323.10 CDJ50496.1 - 0.87 9.5 2.4 10 6.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Peptidase_C58 PF03543.14 CDJ50496.1 - 3.4 7.3 12.4 0.54 9.9 4.0 2.2 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen DUF775 PF05603.12 CDJ50496.1 - 7.1 6.1 9.3 0.16 11.5 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF775) UPF0524 PF15823.5 CDJ50496.1 - 7.3 5.9 7.4 66 2.8 0.0 2.3 2 0 0 2 2 2 0 UPF0524 of C3orf70 DUF4834 PF16118.5 CDJ50496.1 - 8.7 7.4 10.9 0.32 12.0 4.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Gp5_C PF06715.12 CDJ50498.1 - 0.12 12.5 0.2 10 6.5 0.0 3.9 3 0 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) DUF1635 PF07795.11 CDJ50499.1 - 0.012 15.5 0.4 0.024 14.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF3995 PF13160.6 CDJ50499.1 - 1.1 9.6 11.9 2.5 8.5 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) CDK2AP PF09806.9 CDJ50499.1 - 4.6 7.2 14.4 0.42 10.7 2.1 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein ChAPs PF09295.10 CDJ50500.1 - 1.3e-06 27.7 0.0 1.3e-06 27.7 0.0 2.7 4 0 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF4834 PF16118.5 CDJ50501.1 - 0.078 13.9 0.1 0.078 13.9 0.1 7.0 3 2 1 4 4 4 0 Domain of unknown function (DUF4834) Activator_LAG-3 PF11498.8 CDJ50503.1 - 1.5 7.7 43.3 2.6 6.9 43.3 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PcfK PF14058.6 CDJ50504.1 - 1.4 9.2 8.2 1.5 9.1 8.2 1.3 1 0 0 1 1 1 0 PcfK-like protein Presenilin PF01080.17 CDJ50504.1 - 3.9 6.1 6.3 3.8 6.2 6.3 1.1 1 0 0 1 1 1 0 Presenilin DUF3828 PF12883.7 CDJ50505.1 - 0.06 13.7 2.6 0.043 14.2 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3828) SUIM_assoc PF16619.5 CDJ50505.1 - 0.7 10.0 8.9 1.6 8.9 0.2 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ50505.1 - 1.5 8.4 6.7 0.36 10.4 0.6 2.0 2 0 0 2 2 2 0 Spt20 family UQ_con PF00179.26 CDJ50506.1 - 2.6e-53 179.4 0.0 3.3e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ50506.1 - 0.00026 20.7 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ50506.1 - 0.011 16.1 0.0 0.016 15.5 0.0 1.4 1 1 0 1 1 1 0 RWD domain WD40_alt PF14077.6 CDJ50506.1 - 0.024 14.5 0.7 4.3 7.3 0.1 2.8 2 1 1 3 3 3 0 Alternative WD40 repeat motif UEV PF05743.13 CDJ50506.1 - 0.063 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain SUIM_assoc PF16619.5 CDJ50507.1 - 1.6 8.9 26.2 0.73 9.9 2.3 5.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 F-box PF00646.33 CDJ50508.1 - 0.007 16.2 0.3 0.007 16.2 0.3 1.8 2 0 0 2 2 2 1 F-box domain Activator_LAG-3 PF11498.8 CDJ50509.1 - 0.46 9.4 15.1 0.85 8.5 15.1 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SprA-related PF12118.8 CDJ50510.1 - 0.38 9.8 21.5 0.57 9.3 21.5 1.3 1 0 0 1 1 1 0 SprA-related family Tam41_Mmp37 PF09139.11 CDJ50510.1 - 0.73 9.2 8.8 1.1 8.6 8.8 1.2 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial NFACT-C PF11923.8 CDJ50510.1 - 1.9 8.4 5.2 0.86 9.6 2.5 1.8 1 1 1 2 2 2 0 NFACT protein C-terminal domain Radial_spoke PF04712.12 CDJ50511.1 - 5.9e-08 32.1 0.0 6.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein Flu_PB1 PF00602.17 CDJ50511.1 - 0.074 11.2 0.0 0.087 10.9 0.0 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 TSP_1 PF00090.19 CDJ50512.1 - 2e-07 31.1 18.0 3.2e-06 27.3 0.4 3.6 4 0 0 4 4 4 2 Thrombospondin type 1 domain DUF1501 PF07394.12 CDJ50513.1 - 0.41 9.7 6.0 0.46 9.5 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Spt20 PF12090.8 CDJ50513.1 - 0.93 9.1 11.8 1.2 8.7 11.8 1.2 1 0 0 1 1 1 0 Spt20 family Secretin_N_2 PF07655.13 CDJ50514.1 - 0.0014 19.1 10.4 0.0021 18.5 10.4 1.2 1 0 0 1 1 1 1 Secretin N-terminal domain THOC2_N PF16134.5 CDJ50514.1 - 0.086 11.5 1.6 0.12 10.9 1.6 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF3138 PF11336.8 CDJ50514.1 - 0.13 10.9 7.0 0.18 10.4 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Apt1 PF10351.9 CDJ50514.1 - 0.14 11.0 2.4 0.15 10.9 2.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Corona_nucleoca PF00937.18 CDJ50514.1 - 0.99 8.4 6.1 1.2 8.1 6.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SUZ PF12752.7 CDJ50514.1 - 1.6 9.6 8.1 0.14 12.9 2.6 2.1 2 1 0 2 2 2 0 SUZ domain Plasmodium_Vir PF05795.11 CDJ50515.1 - 6.7 6.0 18.3 10 5.4 18.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Not3 PF04065.15 CDJ50516.1 - 7.4e-36 123.7 15.5 7.4e-36 123.7 15.5 2.5 2 1 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component Phage_Gp23 PF10669.9 CDJ50516.1 - 4.1 7.8 7.4 12 6.3 1.8 2.6 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) CAP_N PF01213.19 CDJ50518.1 - 0.00039 20.0 9.2 0.00042 19.9 9.2 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal DNA_pol3_a_NII PF11490.8 CDJ50518.1 - 0.0074 16.2 10.5 0.0074 16.2 10.5 2.0 2 0 0 2 2 2 1 DNA polymerase III polC-type N-terminus II DUF1180 PF06679.12 CDJ50518.1 - 0.031 14.7 8.8 0.037 14.5 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TFB6 PF17110.5 CDJ50518.1 - 0.039 13.7 4.5 0.052 13.3 4.5 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CobT PF06213.12 CDJ50518.1 - 0.092 12.1 17.1 0.1 11.9 17.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SARAF PF06682.12 CDJ50518.1 - 0.1 12.2 16.9 0.12 12.0 16.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2052 PF09747.9 CDJ50518.1 - 0.23 11.6 15.8 0.25 11.4 15.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Ten_N PF06484.12 CDJ50518.1 - 0.33 10.8 8.4 0.33 10.8 8.4 1.0 1 0 0 1 1 1 0 Teneurin Intracellular Region CCDC53 PF10152.9 CDJ50518.1 - 0.38 11.2 17.9 0.44 10.9 17.9 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4698 PF15769.5 CDJ50518.1 - 0.51 9.3 18.1 0.63 9.0 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) MRI PF15325.6 CDJ50518.1 - 0.61 11.2 6.6 0.72 11.0 6.6 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection PGA_cap PF09587.10 CDJ50518.1 - 1.2 8.6 3.7 1.4 8.3 3.7 1.1 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap PIP5K PF01504.18 CDJ50518.1 - 1.4 8.0 9.8 1.8 7.7 9.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase PTPRCAP PF15713.5 CDJ50518.1 - 1.5 9.1 14.5 1.7 8.9 14.5 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4366 PF14283.6 CDJ50518.1 - 1.6 8.8 11.6 1.8 8.6 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Pex14_N PF04695.13 CDJ50518.1 - 1.9 9.1 26.9 2.2 8.9 26.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C PF13299.6 CDJ50518.1 - 1.9 8.6 11.5 2.2 8.4 11.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TAF4 PF05236.14 CDJ50518.1 - 2.5 7.8 19.8 2.9 7.6 19.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Cytochrom_B558a PF05038.13 CDJ50518.1 - 2.6 7.6 9.0 3 7.4 9.0 1.1 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Membralin PF09746.9 CDJ50518.1 - 3.6 6.5 10.0 3.8 6.4 10.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein PPL5 PF18168.1 CDJ50518.1 - 3.8 6.7 7.0 4.5 6.5 7.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Folliculin PF11704.8 CDJ50518.1 - 4.1 7.3 9.1 4.7 7.0 9.1 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Connexin PF00029.19 CDJ50518.1 - 4.1 7.1 10.9 4.7 6.9 10.9 1.1 1 0 0 1 1 1 0 Connexin DUF2828 PF11443.8 CDJ50518.1 - 4.7 5.2 12.4 5.3 5.0 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ50518.1 - 5.3 5.7 19.0 5.4 5.7 19.0 1.0 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 CDJ50518.1 - 5.4 5.9 9.5 5.5 5.9 9.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.6 CDJ50518.1 - 6.2 5.1 5.6 6.6 5.0 5.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ50518.1 - 6.4 5.6 8.0 7.7 5.3 8.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Gti1_Pac2 PF09729.9 CDJ50518.1 - 6.7 6.8 10.1 7.5 6.6 10.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family SpoIIP PF07454.11 CDJ50518.1 - 7.3 6.0 16.8 8.6 5.7 16.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 CDJ50518.1 - 8.1 4.6 11.4 8 4.6 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ50518.1 - 10 5.9 17.4 10 5.8 17.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med15 PF09606.10 CDJ50519.1 - 0.0037 16.0 10.5 0.0037 16.0 10.5 2.3 2 1 1 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal ANAPC_CDC26 PF10471.9 CDJ50519.1 - 0.0056 17.5 37.4 0.037 14.9 7.0 4.5 5 0 0 5 5 5 2 Anaphase-promoting complex APC subunit CDC26 SR-25 PF10500.9 CDJ50519.1 - 0.031 13.9 38.6 0.074 12.7 5.2 3.5 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ50519.1 - 0.036 13.0 35.2 0.019 13.9 7.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Meth_synt_1 PF08267.12 CDJ50519.1 - 0.045 13.3 0.1 0.045 13.3 0.1 1.7 2 0 0 2 2 1 0 Cobalamin-independent synthase, N-terminal domain DUF1645 PF07816.11 CDJ50519.1 - 0.82 10.2 28.5 0.024 15.2 4.7 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1645) Presenilin PF01080.17 CDJ50519.1 - 0.85 8.3 23.2 0.96 8.1 9.3 2.3 2 0 0 2 2 2 0 Presenilin V_ATPase_I PF01496.19 CDJ50519.1 - 0.95 7.3 9.4 2.4 6.0 4.0 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NARP1 PF12569.8 CDJ50519.1 - 2.7 6.8 14.1 0.62 8.9 4.2 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Peptidase_S15 PF02129.18 CDJ50519.1 - 2.7 7.5 11.4 7.3 6.1 4.6 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S64 PF08192.11 CDJ50519.1 - 4.3 5.7 16.5 1.9 6.9 3.9 2.1 2 0 0 2 2 2 0 Peptidase family S64 eIF-3_zeta PF05091.12 CDJ50519.1 - 5.9 5.7 16.0 5.2 5.9 5.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NPR1_interact PF15699.5 CDJ50519.1 - 8.2 7.1 31.5 0.075 13.7 8.5 3.5 4 1 0 4 4 4 0 NPR1 interacting Utp14 PF04615.13 CDJ50523.1 - 0.0018 17.0 2.5 0.0018 17.0 2.5 2.2 2 0 0 2 2 2 1 Utp14 protein EOS1 PF12326.8 CDJ50523.1 - 1.4 8.8 10.0 8.5 6.3 1.3 2.5 2 1 0 2 2 2 0 N-glycosylation protein Sin_N PF04801.13 CDJ50523.1 - 3 6.9 37.6 0.023 13.9 3.9 2.5 2 0 0 2 2 2 0 Sin-like protein conserved region Otopetrin PF03189.13 CDJ50523.1 - 4.5 6.0 6.5 29 3.3 0.0 2.1 2 0 0 2 2 2 0 Otopetrin DUF572 PF04502.13 CDJ50523.1 - 5.8 6.4 27.0 2.8 7.5 9.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) MecA PF05389.12 CDJ50523.1 - 6.3 6.4 13.7 6.5 6.3 1.6 2.4 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Utp14 PF04615.13 CDJ50525.1 - 3.2e-06 26.1 0.9 3.2e-06 26.1 0.9 8.4 4 2 2 7 7 7 2 Utp14 protein Exonuc_VII_L PF02601.15 CDJ50525.1 - 0.00054 19.6 4.1 0.00054 19.6 4.1 9.8 7 3 2 9 9 9 1 Exonuclease VII, large subunit RskA PF10099.9 CDJ50525.1 - 0.0011 19.3 12.7 0.0011 19.3 12.7 22.7 3 3 8 13 13 13 2 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ50526.1 - 0.034 14.2 5.1 0.034 14.2 5.1 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 CDJ50526.1 - 0.39 9.4 3.1 0.47 9.2 3.1 1.1 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 CDJ50526.1 - 0.55 9.6 1.3 0.65 9.3 1.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SARAF PF06682.12 CDJ50526.1 - 2.8 7.5 17.6 3.2 7.3 17.6 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TAF4 PF05236.14 CDJ50526.1 - 4.7 6.9 15.6 9.9 5.8 15.6 1.5 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Aa_trans PF01490.18 CDJ50527.1 - 9.4e-07 27.9 6.2 9.4e-07 27.9 6.2 1.8 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CDJ50527.1 - 0.8 8.7 12.4 0.83 8.6 1.4 2.2 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family Peptidase_M24 PF00557.24 CDJ50528.1 - 4.8e-17 62.3 0.0 6.9e-17 61.8 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 AAA_23 PF13476.6 CDJ50528.1 - 0.055 14.0 9.8 0.094 13.2 9.8 1.5 1 0 0 1 1 1 0 AAA domain DDHD PF02862.17 CDJ50528.1 - 0.07 13.3 11.9 0.024 14.8 8.0 1.9 2 0 0 2 2 2 0 DDHD domain LRRC37AB_C PF14914.6 CDJ50528.1 - 0.23 11.4 12.3 0.5 10.3 12.3 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain SLC12 PF03522.15 CDJ50528.1 - 0.35 9.8 12.5 0.62 9.0 12.5 1.4 1 0 0 1 1 1 0 Solute carrier family 12 MMR1 PF08505.10 CDJ50528.1 - 0.49 10.6 15.6 0.91 9.8 15.6 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CCDC53 PF10152.9 CDJ50528.1 - 0.78 10.1 17.1 0.14 12.6 7.5 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TFIIA PF03153.13 CDJ50528.1 - 0.8 9.6 27.8 0.12 12.3 22.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 CDJ50528.1 - 0.92 8.9 18.8 1.6 8.1 18.8 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Spt20 PF12090.8 CDJ50528.1 - 1.3 8.6 30.0 2.6 7.6 30.0 1.6 1 0 0 1 1 1 0 Spt20 family DUF4366 PF14283.6 CDJ50528.1 - 1.8 8.6 23.2 0.94 9.5 12.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) ALMT PF11744.8 CDJ50528.1 - 2.3 6.9 8.6 3.5 6.4 8.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Orf78 PF06024.12 CDJ50528.1 - 4.7 7.6 6.8 13 6.2 6.8 1.7 1 0 0 1 1 1 0 Orf78 (ac78) DUF4746 PF15928.5 CDJ50528.1 - 5 6.5 13.0 0.08 12.4 4.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 CDJ50528.1 - 5.3 5.2 16.0 0.65 8.2 9.2 2.0 2 0 0 2 2 2 0 CDC45-like protein Presenilin PF01080.17 CDJ50528.1 - 9.9 4.8 18.3 0.23 10.2 11.1 1.7 2 0 0 2 2 2 0 Presenilin Metallophos PF00149.28 CDJ50529.1 - 1.3e-29 104.1 0.0 2e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_2 PF07646.15 CDJ50529.1 - 2.9e-10 39.7 0.8 1.2e-07 31.4 0.0 3.2 2 1 1 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CDJ50529.1 - 5.7e-10 39.0 0.0 0.00051 20.0 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 CDJ50529.1 - 1.5e-09 37.3 0.1 1e-06 28.2 0.0 3.5 2 1 1 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CDJ50529.1 - 1.6e-08 34.4 0.4 0.00049 20.0 0.0 3.7 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ50529.1 - 3.7e-08 33.4 0.2 0.00028 21.0 0.0 3.6 2 1 1 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CDJ50529.1 - 3.5e-05 24.0 0.0 0.83 10.0 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain TFIIA PF03153.13 CDJ50529.1 - 0.55 10.2 18.9 1 9.3 18.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ50529.1 - 5.4 6.9 9.2 9.3 6.1 9.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CitT PF12431.8 CDJ50531.1 - 0.17 12.3 1.1 0.58 10.6 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator Ion_trans PF00520.31 CDJ50533.1 - 0.00023 20.5 0.3 0.00023 20.5 0.3 1.9 1 1 1 2 2 2 1 Ion transport protein UPF0176_N PF17773.1 CDJ50535.1 - 8.5e-20 70.9 0.0 2e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Methyltransf_3 PF01596.17 CDJ50535.1 - 3.3e-16 59.1 0.0 1.4e-06 27.6 0.0 3.4 3 1 0 3 3 3 2 O-methyltransferase Rhodanese PF00581.20 CDJ50535.1 - 3.7e-09 37.1 0.0 8.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_24 PF13578.6 CDJ50535.1 - 7.2e-07 30.2 0.0 2.8e-06 28.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Bombesin PF02044.17 CDJ50535.1 - 0.085 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Bombesin-like peptide tRNA_Me_trans PF03054.16 CDJ50536.1 - 1.2e-76 257.8 0.0 5.3e-69 232.7 0.0 2.6 2 1 0 2 2 2 2 tRNA methyl transferase ThiI PF02568.14 CDJ50536.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Rep_fac-A_3 PF08661.11 CDJ50537.1 - 2.4e-07 31.1 0.0 1.4e-06 28.6 0.0 2.3 3 0 0 3 3 3 1 Replication factor A protein 3 Carb_anhydrase PF00194.21 CDJ50538.1 - 2e-22 80.0 1.8 1.5e-13 50.9 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase SMC_ScpB PF04079.16 CDJ50538.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB MFS_1 PF07690.16 CDJ50539.1 - 2.1e-09 36.8 23.8 5.5e-07 28.8 24.2 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MAP17 PF15807.5 CDJ50539.1 - 0.032 14.5 3.0 0.038 14.2 0.4 2.3 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EMC3_TMCO1 PF01956.16 CDJ50539.1 - 0.11 12.2 0.6 4.6 7.0 0.1 2.6 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like CDC45 PF02724.14 CDJ50540.1 - 0.00054 18.4 0.3 0.00076 17.9 0.3 1.1 1 0 0 1 1 1 1 CDC45-like protein GREB1 PF15782.5 CDJ50540.1 - 0.2 8.8 0.6 0.26 8.3 0.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCDC106 PF15794.5 CDJ50540.1 - 0.9 9.2 7.7 1.6 8.4 7.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 NAM-associated PF14303.6 CDJ50540.1 - 1.8 9.3 10.9 5.8 7.6 10.9 1.8 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Apt1 PF10351.9 CDJ50540.1 - 1.9 7.3 6.8 2.7 6.8 6.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NPR3 PF03666.13 CDJ50540.1 - 2.2 7.0 8.8 3.4 6.4 8.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pheromone PF08015.11 CDJ50540.1 - 9.9 7.3 8.9 3.6 8.7 2.3 3.1 2 0 0 2 2 2 0 Fungal mating-type pheromone CactinC_cactus PF09732.9 CDJ50541.1 - 3.3e-54 182.1 8.4 3.3e-54 182.1 8.4 1.8 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 CDJ50541.1 - 3.8e-46 157.3 2.4 3.8e-46 157.3 2.4 3.4 3 0 0 3 3 3 1 Conserved mid region of cactin Ketoacyl-synt_C PF02801.22 CDJ50541.1 - 0.00088 19.3 0.2 0.00088 19.3 0.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain RAP1 PF07218.11 CDJ50542.1 - 0.12 10.7 2.7 0.15 10.3 2.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Nop53 PF07767.11 CDJ50542.1 - 0.2 11.0 41.8 0.26 10.6 41.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Hamartin PF04388.12 CDJ50542.1 - 0.21 10.2 35.0 0.28 9.8 35.0 1.3 1 0 0 1 1 1 0 Hamartin protein CASP_C PF08172.12 CDJ50542.1 - 0.49 9.7 35.8 0.63 9.3 35.8 1.1 1 0 0 1 1 1 0 CASP C terminal Topoisom_I_N PF02919.15 CDJ50542.1 - 0.52 9.8 12.1 0.022 14.2 5.1 2.1 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Utp14 PF04615.13 CDJ50542.1 - 0.8 8.2 39.2 0.97 7.9 39.2 1.0 1 0 0 1 1 1 0 Utp14 protein LAP1C PF05609.12 CDJ50542.1 - 1.3 8.0 39.1 1.8 7.6 39.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) AMP-binding PF00501.28 CDJ50542.1 - 2.1 6.9 7.5 1.6 7.3 6.3 1.3 1 1 0 1 1 1 0 AMP-binding enzyme DUF572 PF04502.13 CDJ50542.1 - 3.1 7.4 36.7 5 6.6 36.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Draxin PF15550.6 CDJ50542.1 - 4.1 7.2 33.1 5.2 6.8 33.1 1.1 1 0 0 1 1 1 0 Draxin Anticodon_1 PF08264.13 CDJ50543.1 - 1.6e-09 37.9 0.0 4.4e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 CDJ50543.1 - 0.0017 16.7 0.0 0.0017 16.7 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) Macoilin PF09726.9 CDJ50543.1 - 0.0025 16.4 26.7 0.0025 16.4 26.7 3.1 2 1 0 2 2 2 1 Macoilin family AAA_23 PF13476.6 CDJ50543.1 - 0.015 15.8 8.5 0.015 15.8 8.5 3.3 2 1 0 2 2 2 0 AAA domain DnaB_bind PF10410.9 CDJ50543.1 - 0.018 15.2 0.1 0.074 13.3 0.1 2.1 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase tRNA-synt_1g PF09334.11 CDJ50543.1 - 0.074 11.8 0.4 0.18 10.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (M) BUD22 PF09073.10 CDJ50543.1 - 2.5 7.4 49.2 1.3 8.2 7.3 3.3 3 1 0 3 3 3 0 BUD22 tRNA-synt_1 PF00133.22 CDJ50544.1 - 3e-12 45.6 0.1 6.7e-09 34.5 0.0 4.6 4 1 1 5 5 5 3 tRNA synthetases class I (I, L, M and V) BUD22 PF09073.10 CDJ50544.1 - 2.7e-05 23.7 10.0 2.7e-05 23.7 10.0 3.4 2 1 1 3 3 3 1 BUD22 Lin-8 PF03353.15 CDJ50544.1 - 0.0018 17.9 18.9 0.0018 17.9 18.9 4.3 2 1 2 4 4 4 1 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ50544.1 - 0.0025 17.8 11.1 0.0025 17.8 11.1 4.1 2 1 1 3 3 3 1 SPX domain AAA_11 PF13086.6 CDJ50544.1 - 0.0091 15.8 10.8 0.0091 15.8 10.8 4.0 3 1 0 4 4 4 1 AAA domain TFIIA PF03153.13 CDJ50545.1 - 0.027 14.5 19.3 0.031 14.3 19.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM199X PF15814.5 CDJ50545.1 - 0.26 10.3 28.1 0.042 12.9 22.7 1.9 2 0 0 2 2 2 0 Protein family FAM199X Macoilin PF09726.9 CDJ50545.1 - 0.43 9.1 21.3 0.58 8.7 21.3 1.1 1 0 0 1 1 1 0 Macoilin family MAJIN PF15077.6 CDJ50545.1 - 0.7 9.6 10.3 1.1 9.0 10.3 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein Rtf2 PF04641.12 CDJ50545.1 - 1.5 8.1 12.9 2.1 7.6 12.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger PI3K_1B_p101 PF10486.9 CDJ50545.1 - 1.9 6.1 22.4 2.5 5.8 22.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SOBP PF15279.6 CDJ50545.1 - 3.7 8.1 19.4 6.6 7.2 19.4 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein SelP_N PF04592.14 CDJ50545.1 - 3.9 6.8 15.8 5.5 6.3 15.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PGA2 PF07543.12 CDJ50545.1 - 4 7.4 10.9 6.2 6.8 10.9 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 CCDC106 PF15794.5 CDJ50545.1 - 4 7.1 25.2 7.1 6.3 25.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Suf PF05843.14 CDJ50545.1 - 4.9 7.0 18.7 6.1 6.7 18.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PPP4R2 PF09184.11 CDJ50545.1 - 6.8 6.2 18.7 8.5 5.9 18.7 1.1 1 0 0 1 1 1 0 PPP4R2 ASD2 PF08687.11 CDJ50545.1 - 7.7 6.0 16.8 14 5.1 16.8 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 XRCC4 PF06632.12 CDJ50545.1 - 9.1 5.0 19.8 12 4.6 19.8 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Apt1 PF10351.9 CDJ50545.1 - 9.7 4.9 24.3 12 4.6 24.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF155 PF02582.14 CDJ50546.1 - 5.7e-20 72.1 0.0 1.5e-19 70.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 DUF2722 PF10846.8 CDJ50546.1 - 9.6e-05 21.5 2.6 0.00013 21.1 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ50546.1 - 0.00074 19.2 11.0 0.0011 18.7 11.0 1.2 1 0 0 1 1 1 1 Spt20 family SUIM_assoc PF16619.5 CDJ50546.1 - 0.0041 17.2 10.2 0.029 14.4 10.2 2.3 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Suf PF05843.14 CDJ50546.1 - 0.029 14.4 0.9 0.042 13.8 0.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EphA2_TM PF14575.6 CDJ50546.1 - 0.052 14.4 2.1 0.2 12.6 0.5 2.7 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain MFS_Mycoplasma PF07672.13 CDJ50546.1 - 0.1 11.9 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter Otopetrin PF03189.13 CDJ50546.1 - 0.46 9.2 3.2 0.63 8.8 2.9 1.3 1 1 0 1 1 1 0 Otopetrin DUF4834 PF16118.5 CDJ50546.1 - 1.2 10.1 5.3 0.89 10.6 3.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Ribosomal_L27 PF01016.19 CDJ50547.1 - 1.1e-11 44.6 0.3 5.3e-11 42.4 0.3 1.9 1 1 0 1 1 1 1 Ribosomal L27 protein Dynein_light PF01221.18 CDJ50549.1 - 3.1e-21 75.5 0.1 3.4e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 zf-4CXXC_R1 PF10497.9 CDJ50549.1 - 0.0055 16.9 0.0 0.0059 16.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 IZUMO PF15005.6 CDJ50549.1 - 0.11 13.0 0.0 0.13 12.7 0.0 1.0 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated DnaJ PF00226.31 CDJ50550.1 - 7.2e-20 70.9 0.4 1.6e-19 69.8 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 CDJ50550.1 - 4e-18 65.5 0.0 5.5e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain ETRAMP PF09716.10 CDJ50550.1 - 0.86 9.7 0.0 0.86 9.7 0.0 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Ank_2 PF12796.7 CDJ50551.1 - 1.1e-28 99.6 12.3 1.2e-10 41.8 4.2 5.6 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ50551.1 - 1.2e-28 99.0 7.8 8.8e-09 35.7 0.7 7.2 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ50551.1 - 1.8e-26 91.9 10.6 5.1e-11 42.6 0.2 5.9 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CDJ50551.1 - 7.8e-24 83.0 19.2 0.003 17.9 0.0 8.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 CDJ50551.1 - 3.8e-20 69.8 7.6 0.017 15.6 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat Sushi PF00084.20 CDJ50551.1 - 3.6e-07 30.7 0.1 7.4e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) AF-4 PF05110.13 CDJ50551.1 - 0.05 11.7 67.4 0.07 11.2 67.4 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF1772 PF08592.11 CDJ50552.1 - 0.22 11.8 10.9 1.7 9.0 3.8 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) AAA PF00004.29 CDJ50553.1 - 1.5e-42 145.2 0.0 1.2e-37 129.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ50553.1 - 7.6e-09 35.2 0.5 7.6e-09 35.2 0.5 2.2 2 1 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 CDJ50553.1 - 0.00022 21.5 0.1 0.0035 17.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CDJ50553.1 - 0.00055 19.9 0.1 0.0016 18.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDJ50553.1 - 0.00076 19.6 0.1 0.0054 16.9 0.1 2.5 2 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CDJ50553.1 - 0.00096 19.6 0.4 0.0028 18.1 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 CDJ50553.1 - 0.0034 16.6 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CDJ50553.1 - 0.0043 16.4 0.1 0.012 15.0 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CDJ50553.1 - 0.0052 16.2 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.6 CDJ50553.1 - 0.0057 16.8 0.0 0.05 13.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 CDJ50553.1 - 0.0062 16.3 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDJ50553.1 - 0.012 15.3 0.1 0.044 13.5 0.1 1.9 2 1 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CDJ50553.1 - 0.014 15.8 0.0 0.18 12.2 0.0 2.5 3 0 0 3 3 2 0 RNA helicase AAA_19 PF13245.6 CDJ50553.1 - 0.024 15.0 0.2 2.8 8.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain Imm19 PF15563.6 CDJ50553.1 - 0.047 13.2 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Immunity protein 19 IstB_IS21 PF01695.17 CDJ50553.1 - 0.093 12.5 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein Vps4_C PF09336.10 CDJ50553.1 - 0.1 12.6 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 CDJ50553.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CDJ50553.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 CDJ50553.1 - 0.18 11.0 0.2 0.59 9.3 0.2 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 CDJ50553.1 - 0.34 10.8 1.3 32 4.3 0.1 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Ribosomal_L13 PF00572.18 CDJ50554.1 - 2.2e-05 24.7 1.5 0.00021 21.5 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L13 ATP-grasp_2 PF08442.10 CDJ50555.1 - 9.7e-07 28.5 0.0 1.5e-05 24.7 0.1 2.1 1 1 1 2 2 2 1 ATP-grasp domain SR-25 PF10500.9 CDJ50555.1 - 0.013 15.2 12.7 0.013 15.2 12.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 CDJ50555.1 - 0.057 14.1 18.6 0.39 11.4 11.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2464 PF10240.9 CDJ50555.1 - 0.11 12.1 5.8 2.4 7.7 2.5 2.1 2 0 0 2 2 2 0 Multivesicular body subunit 12 CCDC53 PF10152.9 CDJ50555.1 - 0.14 12.6 9.8 0.29 11.5 6.1 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF4175 PF13779.6 CDJ50555.1 - 0.23 9.3 15.4 0.3 8.9 15.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.14 CDJ50555.1 - 0.32 10.9 9.7 0.21 11.5 6.0 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SurA_N_2 PF13623.6 CDJ50555.1 - 0.32 10.8 15.0 0.17 11.7 12.7 1.7 2 0 0 2 2 2 0 SurA N-terminal domain RskA PF10099.9 CDJ50555.1 - 0.34 11.2 14.4 1.9 8.7 4.1 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA MFAP1 PF06991.11 CDJ50555.1 - 0.68 9.7 11.0 1 9.2 11.0 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing TMPIT PF07851.13 CDJ50555.1 - 2.7 7.2 6.7 4.6 6.4 6.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein SurA_N_3 PF13624.6 CDJ50555.1 - 3.1 7.6 15.0 4.5 7.0 13.5 1.8 2 0 0 2 2 2 0 SurA N-terminal domain Ctr PF04145.15 CDJ50555.1 - 4.7 7.8 5.6 24 5.5 0.6 2.3 2 0 0 2 2 2 0 Ctr copper transporter family CNDH2_M PF16869.5 CDJ50555.1 - 5.4 7.7 8.9 12 6.6 0.9 2.3 2 0 0 2 2 2 0 PF16858 ATP11 PF06644.11 CDJ50555.1 - 6.4 6.5 14.4 13 5.5 7.4 2.1 2 0 0 2 2 2 0 ATP11 protein EBP50_C PF09007.11 CDJ50555.1 - 8.1 7.4 14.9 2.4 9.2 3.4 2.2 2 0 0 2 2 2 0 EBP50, C-terminal CPSF100_C PF13299.6 CDJ50555.1 - 8.5 6.5 9.0 36 4.5 0.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PP_kinase_N PF13089.6 CDJ50555.1 - 9 6.7 7.5 19 5.6 7.5 1.5 1 0 0 1 1 1 0 Polyphosphate kinase N-terminal domain DUF1980 PF09323.10 CDJ50555.1 - 9.1 6.1 11.8 28 4.6 6.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Citrate_bind PF16114.5 CDJ50556.1 - 4.1e-06 26.4 0.3 7.5e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 ATP citrate lyase citrate-binding FTCD_C PF04961.12 CDJ50556.1 - 0.0098 15.7 9.1 0.015 15.0 9.1 1.2 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase eIF-3_zeta PF05091.12 CDJ50556.1 - 0.017 14.1 6.5 0.021 13.8 6.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_60s PF00428.19 CDJ50556.1 - 0.037 14.6 20.8 0.71 10.5 4.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ50556.1 - 0.05 13.6 23.5 0.056 13.4 23.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit C8 PF08742.11 CDJ50556.1 - 0.072 13.5 0.9 0.12 12.8 0.9 1.5 1 0 0 1 1 1 0 C8 domain Serinc PF03348.15 CDJ50556.1 - 0.11 11.5 2.3 0.13 11.1 2.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Med3 PF11593.8 CDJ50556.1 - 0.12 11.6 27.2 0.19 10.9 27.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RAP1 PF07218.11 CDJ50556.1 - 0.13 10.5 4.0 0.14 10.4 4.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.13 CDJ50556.1 - 0.16 10.1 17.9 0.21 9.6 17.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FAM110_C PF14160.6 CDJ50556.1 - 0.17 12.9 7.2 1.9 9.6 2.1 2.1 2 0 0 2 2 2 0 Centrosome-associated C terminus Presenilin PF01080.17 CDJ50556.1 - 0.26 10.0 9.8 0.33 9.7 9.8 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ50556.1 - 0.27 10.8 25.3 0.034 13.8 19.9 1.8 2 0 0 2 2 2 0 Spt20 family DUF3402 PF11882.8 CDJ50556.1 - 1.8 7.6 8.6 1.1 8.3 6.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) Coilin_N PF15862.5 CDJ50556.1 - 2.7 7.8 13.2 0.3 10.9 6.6 2.0 2 0 0 2 2 2 0 Coilin N-terminus RskA PF10099.9 CDJ50556.1 - 3.8 7.8 31.5 2e+02 2.1 31.5 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ50556.1 - 4.6 6.3 15.7 6.9 5.8 15.7 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region DUF3824 PF12868.7 CDJ50556.1 - 6.2 7.5 16.3 1.1 9.9 8.1 2.3 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) SspB PF04386.13 CDJ50556.1 - 8.9 6.2 13.0 1.7 8.5 8.8 1.7 2 0 0 2 2 2 0 Stringent starvation protein B Ligase_CoA PF00549.19 CDJ50557.1 - 2.9e-11 43.4 1.7 4.9e-11 42.7 1.7 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CDJ50557.1 - 0.056 13.2 5.2 0.37 10.6 4.8 2.2 1 1 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Neur_chan_memb PF02932.16 CDJ50557.1 - 3.1 7.8 4.0 5.1 7.1 4.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Bromodomain PF00439.25 CDJ50558.1 - 0.00033 20.7 0.0 0.00063 19.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain SR-25 PF10500.9 CDJ50558.1 - 0.003 17.2 23.0 0.003 17.2 23.0 16.1 9 4 5 15 15 15 3 Nuclear RNA-splicing-associated protein SelK_SelG PF10961.8 CDJ50559.1 - 0.089 13.4 0.1 2.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Selenoprotein SelK_SelG DUF2722 PF10846.8 CDJ50560.1 - 9.5e-06 24.8 9.3 0.00023 20.3 0.2 6.1 4 1 2 6 6 6 2 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ50560.1 - 0.0047 16.6 6.0 0.0047 16.6 6.0 5.4 5 0 0 5 5 5 2 Nuclear RNA-splicing-associated protein CrgA PF06781.12 CDJ50560.1 - 0.39 10.8 0.1 0.39 10.8 0.1 4.8 4 1 0 4 4 4 0 Cell division protein CrgA EOS1 PF12326.8 CDJ50560.1 - 0.43 10.5 0.0 0.43 10.5 0.0 4.9 3 2 1 4 4 4 0 N-glycosylation protein DUF4366 PF14283.6 CDJ50560.1 - 0.48 10.5 0.0 0.48 10.5 0.0 5.8 5 1 0 6 6 6 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 CDJ50560.1 - 3.6 6.2 52.0 1.3 7.7 3.2 4.3 4 0 0 4 4 4 0 Presenilin DUF2207 PF09972.9 CDJ50560.1 - 5.6 5.6 9.2 3 6.5 0.0 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Vfa1 PF08432.10 CDJ50560.1 - 6.6 7.0 41.6 6.3 7.1 4.0 4.7 4 0 0 4 4 4 0 AAA-ATPase Vps4-associated protein 1 TB2_DP1_HVA22 PF03134.19 CDJ50561.1 - 4.2e-27 93.9 5.2 5.9e-27 93.4 5.2 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DEAD PF00270.29 CDJ50562.1 - 2.8e-43 147.7 0.6 8.8e-43 146.1 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ50562.1 - 3.8e-29 101.3 0.4 3.8e-29 101.3 0.4 2.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Presenilin PF01080.17 CDJ50562.1 - 0.00013 20.9 4.9 0.00017 20.5 4.9 1.1 1 0 0 1 1 1 1 Presenilin DDHD PF02862.17 CDJ50562.1 - 0.019 15.2 1.9 0.034 14.3 1.9 1.5 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 CDJ50562.1 - 0.02 14.9 22.5 0.028 14.4 22.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Helicase_RecD PF05127.14 CDJ50562.1 - 0.046 13.6 0.0 0.046 13.6 0.0 2.4 2 0 0 2 2 2 0 Helicase CMS1 PF14617.6 CDJ50562.1 - 0.16 11.2 0.0 0.16 11.2 0.0 2.8 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit PapG_C PF03628.13 CDJ50562.1 - 0.17 11.8 0.0 7.8 6.4 0.0 2.5 2 0 0 2 2 2 0 PapG chaperone-binding domain Ndc1_Nup PF09531.10 CDJ50562.1 - 0.19 10.4 3.0 0.25 10.0 3.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.13 CDJ50562.1 - 0.63 9.8 6.6 0.44 10.3 4.9 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Zip PF02535.22 CDJ50562.1 - 0.69 9.1 4.1 0.93 8.6 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 CDJ50562.1 - 1.1 8.1 6.1 1.7 7.5 6.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_22 PF13401.6 CDJ50562.1 - 3.2 8.0 6.3 0.66 10.3 0.2 3.0 3 1 0 3 3 2 0 AAA domain Gti1_Pac2 PF09729.9 CDJ50562.1 - 4.3 7.4 11.7 6.8 6.7 11.7 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family SARAF PF06682.12 CDJ50565.1 - 0.0024 17.6 4.3 0.0024 17.6 4.3 8.6 5 3 3 8 8 8 2 SOCE-associated regulatory factor of calcium homoeostasis SKA1 PF07160.12 CDJ50566.1 - 1.7 8.4 3.8 1.3 8.8 0.3 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4614 PF15391.6 CDJ50566.1 - 2.2 8.2 14.3 0.46 10.5 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Secretin_N_2 PF07655.13 CDJ50566.1 - 5.9 7.5 22.7 9.7 6.8 9.5 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4667 PF15700.5 CDJ50567.1 - 0.029 14.5 21.2 0.039 14.1 21.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ50567.1 - 0.14 11.8 26.6 0.22 11.1 26.6 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ50567.1 - 0.3 11.4 29.4 1 9.7 29.4 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA FAP PF07174.11 CDJ50567.1 - 0.39 10.1 17.1 0.41 10.0 17.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) RAB3GAP2_N PF14655.6 CDJ50567.1 - 1 8.6 14.8 1.1 8.5 14.8 1.3 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Mito_fiss_reg PF05308.11 CDJ50567.1 - 3.3 7.7 18.3 3.9 7.5 18.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator BAF1_ABF1 PF04684.13 CDJ50567.1 - 6.3 5.7 24.1 7.2 5.5 24.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CAF-1_p60_C PF15512.6 CDJ50567.1 - 6.5 7.2 24.6 8.4 6.8 24.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal TFIIA PF03153.13 CDJ50567.1 - 6.7 6.6 42.6 7.9 6.4 42.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FHIPEP PF00771.20 CDJ50567.1 - 7.7 4.8 8.9 9.1 4.6 8.9 1.1 1 0 0 1 1 1 0 FHIPEP family Hamartin PF04388.12 CDJ50567.1 - 8.1 5.0 20.1 9.1 4.8 20.1 1.0 1 0 0 1 1 1 0 Hamartin protein Suf PF05843.14 CDJ50567.1 - 8.6 6.2 24.2 10 6.0 24.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DivIC PF04977.15 CDJ50567.1 - 8.6 6.2 14.1 18 5.2 14.1 1.5 1 0 0 1 1 1 0 Septum formation initiator Mucin PF01456.17 CDJ50568.1 - 0.0085 16.1 0.1 0.0085 16.1 0.1 5.5 3 1 0 3 3 3 1 Mucin-like glycoprotein Hydin_ADK PF17213.3 CDJ50568.1 - 0.38 11.0 0.0 0.38 11.0 0.0 5.2 3 1 1 4 4 4 0 Hydin Adenylate kinase-like domain Trypan_PARP PF05887.11 CDJ50568.1 - 0.41 10.6 0.1 0.41 10.6 0.1 4.0 3 1 1 4 4 4 0 Procyclic acidic repetitive protein (PARP) CRA PF06589.11 CDJ50568.1 - 0.48 10.5 0.0 0.48 10.5 0.0 4.3 2 1 0 2 2 2 0 Circumsporozoite-related antigen (CRA) G0-G1_switch_2 PF15103.6 CDJ50569.1 - 0.0027 18.1 12.0 0.0045 17.4 2.4 2.2 2 0 0 2 2 2 1 G0/G1 switch protein 2 RskA PF10099.9 CDJ50569.1 - 0.0052 17.1 43.3 0.0072 16.6 15.6 2.7 1 1 1 2 2 2 1 Anti-sigma-K factor rskA MAT1 PF06391.13 CDJ50569.1 - 0.014 15.3 21.4 0.18 11.6 2.7 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 AAA_23 PF13476.6 CDJ50569.1 - 0.02 15.4 3.7 0.02 15.4 3.7 2.1 2 0 0 2 2 2 0 AAA domain DUF2828 PF11443.8 CDJ50569.1 - 0.027 12.6 9.3 0.036 12.2 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF572 PF04502.13 CDJ50569.1 - 0.028 14.0 19.0 0.038 13.6 19.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4179 PF13786.6 CDJ50569.1 - 0.12 12.8 9.4 0.73 10.3 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) RNase_H2_suC PF08615.11 CDJ50569.1 - 0.14 12.3 7.4 1.3 9.2 1.8 2.1 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MAM33 PF02330.16 CDJ50569.1 - 0.16 11.9 14.6 0.78 9.7 2.1 2.1 2 0 0 2 2 2 0 Mitochondrial glycoprotein EIIBC-GUT_N PF03612.14 CDJ50569.1 - 0.22 11.3 14.5 0.38 10.5 3.8 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus LAP1C PF05609.12 CDJ50569.1 - 0.29 10.2 21.9 0.35 9.9 21.9 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peroxin-13_N PF04088.13 CDJ50569.1 - 0.3 11.4 9.5 2.7 8.3 2.0 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Ndc1_Nup PF09531.10 CDJ50569.1 - 0.34 9.5 22.9 0.42 9.2 22.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1644 PF07800.12 CDJ50569.1 - 0.39 10.8 13.7 1.1 9.3 5.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) FHIPEP PF00771.20 CDJ50569.1 - 0.51 8.7 15.0 0.47 8.9 1.8 2.1 2 0 0 2 2 2 0 FHIPEP family DUF3504 PF12012.8 CDJ50569.1 - 0.55 10.1 11.0 1.1 9.2 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) Thg1C PF14413.6 CDJ50569.1 - 0.58 10.3 13.9 3.2 7.9 1.0 2.2 2 0 0 2 2 2 0 Thg1 C terminal domain CIAPIN1 PF05093.13 CDJ50569.1 - 0.59 10.7 11.2 4.3 7.9 3.2 2.4 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Tim54 PF11711.8 CDJ50569.1 - 0.6 8.8 14.4 1.8 7.2 6.1 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Zn_peptidase PF04228.13 CDJ50569.1 - 0.71 9.3 18.7 0.24 10.8 7.2 2.2 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase SpoIIP PF07454.11 CDJ50569.1 - 0.76 9.2 16.8 1.4 8.3 1.5 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Peptidase_S49_N PF08496.10 CDJ50569.1 - 0.82 9.7 14.3 2.7 8.0 1.7 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SPX PF03105.19 CDJ50569.1 - 0.83 9.5 23.7 1.3 8.9 23.7 1.3 1 0 0 1 1 1 0 SPX domain DUF2367 PF10164.9 CDJ50569.1 - 0.9 10.1 15.6 2.2 8.8 4.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) SART-1 PF03343.13 CDJ50569.1 - 0.9 8.0 21.4 1.4 7.4 21.4 1.2 1 0 0 1 1 1 0 SART-1 family Peptidase_S64 PF08192.11 CDJ50569.1 - 1.1 7.6 27.2 1.5 7.3 27.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3464 PF11947.8 CDJ50569.1 - 1.1 9.0 18.4 1 9.1 5.9 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF3408 PF11888.8 CDJ50569.1 - 1.1 9.4 16.3 2.7 8.1 6.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF523 PF04463.12 CDJ50569.1 - 1.3 9.1 11.0 0.26 11.3 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF523) RLL PF10036.9 CDJ50569.1 - 1.3 8.8 19.4 3 7.6 3.7 2.2 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein EphA2_TM PF14575.6 CDJ50569.1 - 1.4 9.8 11.8 9.4 7.2 0.5 2.7 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain U1snRNP70_N PF12220.8 CDJ50569.1 - 1.5 9.5 18.5 5.4 7.7 2.8 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TFB6 PF17110.5 CDJ50569.1 - 2 8.2 9.3 5.6 6.7 2.7 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH RAP1 PF07218.11 CDJ50569.1 - 2 6.6 11.8 2.2 6.4 11.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Rsc14 PF08586.10 CDJ50569.1 - 2.2 9.2 9.8 6.1 7.7 0.5 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit E7 PF00527.18 CDJ50569.1 - 2.3 8.5 15.4 0.68 10.2 4.5 2.2 2 0 0 2 2 2 0 E7 protein, Early protein OATP PF03137.20 CDJ50569.1 - 2.3 6.4 10.0 1.3 7.2 3.1 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Utp14 PF04615.13 CDJ50569.1 - 2.6 6.5 25.4 3 6.3 25.4 1.0 1 0 0 1 1 1 0 Utp14 protein Lin-8 PF03353.15 CDJ50569.1 - 2.8 7.4 24.8 1 8.9 9.8 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ50569.1 - 2.9 7.4 41.9 11 5.5 42.1 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Conotoxin PF02950.17 CDJ50569.1 - 2.9 9.0 20.3 0.56 11.3 4.6 2.6 2 1 1 3 3 2 0 Conotoxin Folate_carrier PF01770.18 CDJ50569.1 - 3 6.5 7.2 7.7 5.1 2.5 2.1 2 0 0 2 2 2 0 Reduced folate carrier Rer1 PF03248.13 CDJ50569.1 - 3 7.5 4.6 1.5 8.6 0.7 1.9 2 0 0 2 2 2 0 Rer1 family Glt_symporter PF03616.14 CDJ50569.1 - 3.2 6.3 10.4 1.1 7.9 0.4 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter RNA_pol_Rbc25 PF08292.12 CDJ50569.1 - 3.5 7.9 12.2 3.1 8.0 3.0 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 DUF1266 PF06889.11 CDJ50569.1 - 4.6 7.2 13.7 3.4 7.7 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) RuvC_III PF18541.1 CDJ50569.1 - 4.9 7.1 15.4 2.6 7.9 2.1 2.1 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 DUF4770 PF15994.5 CDJ50569.1 - 5.1 7.3 22.2 4.1 7.6 8.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) GN3L_Grn1 PF08701.11 CDJ50569.1 - 5.2 7.3 35.7 0.47 10.6 11.0 2.2 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase DUF4064 PF13273.6 CDJ50569.1 - 5.8 7.3 5.8 20 5.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Hamartin PF04388.12 CDJ50569.1 - 5.9 5.4 22.3 7.1 5.2 22.3 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4366 PF14283.6 CDJ50569.1 - 6.9 6.7 12.2 4.5 7.3 4.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Aquarius_N PF16399.5 CDJ50569.1 - 7.3 4.5 13.1 0.5 8.3 1.4 2.0 2 0 0 2 2 2 0 Intron-binding protein aquarius N-terminus BRF1 PF07741.13 CDJ50569.1 - 8.8 6.7 20.9 1.3 9.4 3.4 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Ferlin_C PF16165.5 CDJ50569.1 - 8.9 6.2 6.9 37 4.2 0.1 2.1 2 0 0 2 2 2 0 Ferlin C-terminus ATG22 PF11700.8 CDJ50569.1 - 9.4 4.7 10.4 5.1 5.6 3.0 2.1 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Pet20 PF08692.10 CDJ50569.1 - 9.5 7.0 9.1 18 6.0 2.0 2.2 2 0 0 2 2 2 0 Mitochondrial protein Pet20 FAM176 PF14851.6 CDJ50569.1 - 9.6 5.9 14.2 0.94 9.1 0.6 2.4 2 1 0 2 2 2 0 FAM176 family Centro_C10orf90 PF17730.1 CDJ50570.1 - 0.69 8.6 9.6 0.71 8.6 9.6 1.0 1 0 0 1 1 1 0 Centrosomal C10orf90 Fe_hyd_lg_C PF02906.14 CDJ50572.1 - 6.1e-24 85.0 0.0 6.4e-07 29.3 0.0 4.7 4 1 0 4 4 4 3 Iron only hydrogenase large subunit, C-terminal domain Spt20 PF12090.8 CDJ50572.1 - 0.00026 20.7 3.4 0.00026 20.7 3.4 5.6 5 1 1 6 6 6 1 Spt20 family DUF2722 PF10846.8 CDJ50572.1 - 0.00052 19.1 14.8 0.0011 18.0 2.8 4.9 4 1 1 5 5 5 2 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ50572.1 - 0.00067 20.0 6.3 0.00067 20.0 6.3 11.6 5 3 5 10 10 10 1 Anti-sigma-K factor rskA TCP PF03634.13 CDJ50572.1 - 0.0018 18.9 10.9 0.0018 18.9 10.9 4.7 4 2 0 4 4 4 1 TCP family transcription factor F-box-like_2 PF13013.6 CDJ50572.1 - 0.2 11.7 3.2 0.49 10.4 0.2 2.5 2 0 0 2 2 2 0 F-box-like domain DUF4834 PF16118.5 CDJ50573.1 - 0.011 16.7 6.0 0.41 11.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4484 PF14831.6 CDJ50573.1 - 0.019 15.0 2.1 0.023 14.7 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) HemY_N PF07219.13 CDJ50573.1 - 0.15 12.3 0.1 0.15 12.3 0.1 2.0 1 1 1 2 2 2 0 HemY protein N-terminus OAD_gamma PF04277.13 CDJ50573.1 - 0.21 12.2 0.1 2.3 8.9 0.0 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain XK-related PF09815.9 CDJ50573.1 - 0.7 8.9 3.8 1 8.4 3.8 1.2 1 0 0 1 1 1 0 XK-related protein GRP PF07172.11 CDJ50573.1 - 0.94 10.2 2.3 1.1 10.0 0.2 1.8 2 0 0 2 2 2 0 Glycine rich protein family Activator_LAG-3 PF11498.8 CDJ50573.1 - 0.94 8.4 43.4 1.3 7.9 43.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Rpp20 PF12328.8 CDJ50573.1 - 1 9.3 5.1 7.4 6.5 0.7 2.0 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Spt20 PF12090.8 CDJ50573.1 - 1.7 8.2 31.1 1.1 8.8 14.2 2.0 2 0 0 2 2 2 0 Spt20 family ANAPC_CDC26 PF10471.9 CDJ50573.1 - 8 7.4 27.8 12 6.8 10.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 FAM150 PF15129.6 CDJ50573.1 - 8.1 6.6 9.1 6.3 7.0 1.5 2.1 2 0 0 2 2 2 0 FAM150 family TMEM208_SND2 PF05620.11 CDJ50573.1 - 8.3 6.2 9.8 8.4 6.1 0.1 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 EFG_IV PF03764.18 CDJ50574.1 - 1.7e-37 127.9 0.3 3e-37 127.1 0.3 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 CDJ50574.1 - 7.4e-26 90.1 0.1 1.5e-25 89.1 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CDJ50574.1 - 2.5e-19 69.1 0.0 5.9e-10 39.0 0.0 2.8 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDJ50574.1 - 1.5e-09 38.1 0.1 3.1e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 CDJ50574.1 - 8.2e-05 22.2 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Apt1 PF10351.9 CDJ50574.1 - 0.0005 19.1 8.5 0.00067 18.6 8.5 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain SPX PF03105.19 CDJ50574.1 - 0.00087 19.3 8.9 0.0014 18.6 8.9 1.4 1 0 0 1 1 1 1 SPX domain RF3_C PF16658.5 CDJ50574.1 - 0.0015 18.3 0.1 0.003 17.4 0.1 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain RNA_pol_Rpc4 PF05132.14 CDJ50574.1 - 0.094 13.1 4.0 7.3 7.0 4.7 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Zip PF02535.22 CDJ50574.1 - 0.28 10.4 2.3 0.42 9.8 2.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SOG2 PF10428.9 CDJ50574.1 - 0.36 10.0 17.6 0.037 13.2 12.2 1.9 2 0 0 2 2 2 0 RAM signalling pathway protein PNISR PF15996.5 CDJ50574.1 - 0.37 11.1 4.2 0.91 9.8 4.2 1.6 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR NPR3 PF03666.13 CDJ50574.1 - 0.46 9.2 11.2 0.77 8.5 11.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 CDJ50574.1 - 0.52 8.4 6.5 0.74 7.9 6.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 CDJ50574.1 - 0.52 8.5 5.5 0.76 8.0 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ50574.1 - 2.4 6.8 10.7 4.1 6.1 10.7 1.3 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 CDJ50574.1 - 6.9 5.3 7.6 11 4.7 7.6 1.2 1 0 0 1 1 1 0 Raftlin Spt20 PF12090.8 CDJ50575.1 - 5.1e-05 23.0 50.1 0.018 14.7 25.6 2.2 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ50575.1 - 0.044 12.7 44.9 0.056 12.4 12.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Fes1 PF08609.10 CDJ50575.1 - 0.063 14.2 1.6 0.063 14.2 1.6 3.2 2 1 0 2 2 1 0 Nucleotide exchange factor Fes1 DUF4834 PF16118.5 CDJ50575.1 - 0.3 12.1 22.7 0.84 10.6 4.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF719 PF05334.13 CDJ50575.1 - 0.31 11.2 15.1 0.33 11.1 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF1387 PF07139.11 CDJ50575.1 - 0.57 9.9 20.2 1.1 8.9 20.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) EOS1 PF12326.8 CDJ50575.1 - 0.82 9.6 6.3 7 6.5 0.2 2.1 2 0 0 2 2 2 0 N-glycosylation protein Thg1C PF14413.6 CDJ50575.1 - 1.3 9.2 12.7 0.7 10.1 0.2 2.4 2 0 0 2 2 2 0 Thg1 C terminal domain Peroxin-3 PF04882.12 CDJ50575.1 - 1.3 7.9 20.7 2 7.3 20.7 1.3 1 0 0 1 1 1 0 Peroxin-3 Connexin PF00029.19 CDJ50575.1 - 1.5 8.5 11.8 5.8 6.6 4.4 2.1 2 0 0 2 2 2 0 Connexin MPM1 PF17234.2 CDJ50575.1 - 1.6 8.9 18.2 0.43 10.8 1.6 2.4 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 RskA PF10099.9 CDJ50575.1 - 1.7 8.9 53.4 0.088 13.1 14.6 3.2 1 1 2 3 3 3 0 Anti-sigma-K factor rskA DUF3408 PF11888.8 CDJ50575.1 - 1.8 8.7 19.7 1.7 8.8 8.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) RICTOR_N PF14664.6 CDJ50575.1 - 2 7.3 4.0 8.1 5.3 1.1 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term EPL1 PF10513.9 CDJ50575.1 - 2 8.8 24.2 1 9.7 2.6 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Peptidase_S49_N PF08496.10 CDJ50575.1 - 2.2 8.3 12.2 3.2 7.8 1.2 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CTU2 PF10288.9 CDJ50575.1 - 2.6 8.3 18.2 3.2 8.0 0.9 2.7 3 0 0 3 3 2 0 Cytoplasmic tRNA 2-thiolation protein 2 FAM76 PF16046.5 CDJ50575.1 - 2.8 7.2 16.3 3.1 7.1 0.7 2.3 2 0 0 2 2 2 0 FAM76 protein Apc15p PF05841.11 CDJ50575.1 - 3 8.7 27.0 0.72 10.7 3.7 2.5 2 0 0 2 2 2 0 Apc15p protein HA2 PF04408.23 CDJ50575.1 - 3.3 8.0 16.2 6.4 7.1 0.9 3.0 3 1 0 3 3 3 0 Helicase associated domain (HA2) PRC2_HTH_1 PF18118.1 CDJ50575.1 - 4.5 8.1 14.7 3.5 8.5 0.4 2.5 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Peroxin-13_N PF04088.13 CDJ50575.1 - 4.5 7.5 10.9 6.3 7.1 2.4 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Eapp_C PF10238.9 CDJ50575.1 - 5.1 7.2 20.8 2 8.4 2.2 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein Paf1 PF03985.13 CDJ50575.1 - 5.1 6.0 26.2 2.7 6.9 4.4 2.2 2 0 0 2 2 2 0 Paf1 RNase_H2_suC PF08615.11 CDJ50575.1 - 6.7 6.9 10.6 5.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF1980 PF09323.10 CDJ50575.1 - 7 6.5 14.1 3.1 7.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) NPR1_interact PF15699.5 CDJ50575.1 - 7.8 7.2 18.7 11 6.7 7.9 2.6 2 0 0 2 2 2 0 NPR1 interacting Hamartin PF04388.12 CDJ50575.1 - 8.5 4.9 16.6 11 4.6 16.6 1.2 1 0 0 1 1 1 0 Hamartin protein ATAD4 PF15321.6 CDJ50575.1 - 9.5 7.6 14.4 26 6.2 1.0 2.7 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Pkinase PF00069.25 CDJ50576.1 - 6.1e-64 215.9 0.0 8.6e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ50576.1 - 1.2e-32 113.3 0.0 1.8e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ50576.1 - 0.00052 19.4 0.0 0.00082 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ50576.1 - 0.34 10.8 7.9 6.9 6.5 7.9 2.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family TFIIA PF03153.13 CDJ50576.1 - 2.5 8.0 12.9 4.6 7.1 12.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ50576.1 - 9.5 5.1 17.6 8 5.4 16.0 1.7 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ribosom_S12_S23 PF00164.25 CDJ50577.1 - 3.5e-51 171.6 0.4 4.4e-51 171.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Peptidase_M6 PF05547.11 CDJ50577.1 - 0.19 10.0 0.0 0.23 9.8 0.0 1.0 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 EMP24_GP25L PF01105.24 CDJ50578.1 - 7.5e-25 87.9 0.0 3.2e-19 69.6 0.0 2.5 1 1 1 2 2 2 2 emp24/gp25L/p24 family/GOLD CPT PF07931.12 CDJ50578.1 - 0.028 14.3 0.3 0.15 11.9 0.3 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF4179 PF13786.6 CDJ50578.1 - 0.084 13.4 4.1 27 5.3 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Bystin PF05291.11 CDJ50580.1 - 4.4e-113 377.4 0.9 6.9e-113 376.8 0.9 1.2 1 0 0 1 1 1 1 Bystin Ribosomal_L36e PF01158.18 CDJ50581.1 - 2.5e-38 130.2 4.3 2.8e-38 130.1 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Med4 PF10018.9 CDJ50582.1 - 0.012 15.3 1.5 0.012 15.3 1.5 3.9 4 0 0 4 4 4 0 Vitamin-D-receptor interacting Mediator subunit 4 MCU PF04678.13 CDJ50582.1 - 1.5 8.9 9.8 0.81 9.8 0.2 2.7 2 0 0 2 2 2 0 Mitochondrial calcium uniporter HBS1_N PF08938.10 CDJ50582.1 - 4.5 7.6 9.0 0.094 13.0 0.4 2.7 2 1 0 2 2 2 0 HBS1 N-terminus DUF724 PF05266.14 CDJ50583.1 - 6.9 6.4 44.2 2.3 8.0 9.5 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF724) SPX PF03105.19 CDJ50584.1 - 5.6e-05 23.2 6.1 5.6e-05 23.2 6.1 1.6 2 0 0 2 2 2 1 SPX domain RPE65 PF03055.15 CDJ50584.1 - 0.0026 17.0 2.7 0.0026 17.0 2.7 1.5 2 0 0 2 2 2 1 Retinal pigment epithelial membrane protein Presenilin PF01080.17 CDJ50584.1 - 0.0061 15.4 25.4 0.011 14.5 22.1 2.1 2 0 0 2 2 2 1 Presenilin DDHD PF02862.17 CDJ50584.1 - 0.053 13.7 18.6 0.098 12.8 15.1 2.2 2 0 0 2 2 2 0 DDHD domain PIP5K PF01504.18 CDJ50584.1 - 0.084 12.1 11.7 1.3 8.1 12.5 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase CCSAP PF15748.5 CDJ50584.1 - 0.14 12.4 25.9 0.032 14.4 19.2 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 CDJ50584.1 - 0.23 9.7 20.3 0.04 12.2 15.9 1.7 2 0 0 2 2 2 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ50584.1 - 0.23 11.3 25.6 0.047 13.5 19.8 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Plasmodium_Vir PF05795.11 CDJ50584.1 - 0.28 10.5 10.9 0.53 9.6 10.9 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Gti1_Pac2 PF09729.9 CDJ50584.1 - 0.33 11.0 20.0 1.3 9.1 15.8 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family SpoIIP PF07454.11 CDJ50584.1 - 0.37 10.2 22.2 0.12 11.8 16.7 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Ndc1_Nup PF09531.10 CDJ50584.1 - 0.47 9.1 15.5 0.016 13.9 9.3 1.8 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup GAGA_bind PF06217.12 CDJ50584.1 - 0.62 10.3 20.7 0.061 13.6 15.0 1.9 2 0 0 2 2 2 0 GAGA binding protein-like family UPF0565 PF10561.9 CDJ50584.1 - 0.76 8.9 8.6 0.05 12.8 3.5 1.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Spore_coat_CotO PF14153.6 CDJ50584.1 - 0.93 9.4 39.6 0.19 11.7 31.5 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Neur_chan_memb PF02932.16 CDJ50584.1 - 0.96 9.5 19.7 0.13 12.3 13.2 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PNISR PF15996.5 CDJ50584.1 - 1.1 9.5 29.8 0.35 11.1 22.5 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR CKAP2_C PF15297.6 CDJ50584.1 - 1.3 8.1 18.4 0.11 11.5 13.0 1.7 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Tim54 PF11711.8 CDJ50584.1 - 1.3 7.7 19.2 0.22 10.3 14.1 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 PPP4R2 PF09184.11 CDJ50584.1 - 1.5 8.4 12.7 0.38 10.3 9.3 1.7 2 0 0 2 2 2 0 PPP4R2 YABBY PF04690.13 CDJ50584.1 - 2.1 8.9 17.8 1.3 9.5 12.8 2.3 2 0 0 2 2 2 0 YABBY protein CLN3 PF02487.17 CDJ50584.1 - 3 6.8 16.0 9.6 5.1 15.3 1.9 2 0 0 2 2 2 0 CLN3 protein Otopetrin PF03189.13 CDJ50584.1 - 3.2 6.5 11.4 1.3 7.7 7.2 1.9 2 0 0 2 2 2 0 Otopetrin DUF908 PF06012.12 CDJ50584.1 - 4.1 6.7 19.9 3.5 6.9 15.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) PTPRCAP PF15713.5 CDJ50584.1 - 4.3 7.6 28.8 2.2 8.6 22.5 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Endostatin PF06482.11 CDJ50584.1 - 5.7 6.3 24.2 0.48 9.8 17.0 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin DUF2058 PF09831.9 CDJ50584.1 - 5.9 7.0 43.9 2.3 8.3 4.8 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Pkinase_fungal PF17667.1 CDJ50584.1 - 6 5.5 13.7 0.49 9.1 9.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase IHABP4_N PF16174.5 CDJ50584.1 - 7.2 7.2 36.8 1.6 9.3 26.3 3.0 3 0 0 3 3 3 0 Intracellular hyaluronan-binding protein 4 N-terminal FAM60A PF15396.6 CDJ50584.1 - 7.2 6.5 24.3 5.5 6.9 17.2 2.3 2 0 0 2 2 2 0 Protein Family FAM60A MIF4G_like_2 PF09090.11 CDJ50585.1 - 5.2e-10 39.2 0.1 5.2e-10 39.2 0.1 3.7 4 0 0 4 4 4 1 MIF4G like DUF4255 PF14065.6 CDJ50585.1 - 0.00063 19.5 1.1 0.00063 19.5 1.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4255) DUF2722 PF10846.8 CDJ50585.1 - 0.3 10.0 45.2 0.0082 15.1 14.7 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ50585.1 - 4.6 8.3 36.3 1.2 10.1 0.5 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) RT_RNaseH_2 PF17919.1 CDJ50586.1 - 9.2e-25 86.6 0.1 1.3e-24 86.2 0.1 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ50586.1 - 1e-13 51.5 0.0 1.6e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Scramblase PF03803.15 CDJ50586.1 - 0.066 12.5 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Scramblase Presenilin PF01080.17 CDJ50588.1 - 3.7 6.2 23.4 4.2 6.0 23.4 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CDJ50588.1 - 4 6.1 25.9 4.7 5.9 25.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NST1 PF13945.6 CDJ50588.1 - 5.9 7.0 23.5 8.8 6.4 23.5 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator FAM76 PF16046.5 CDJ50588.1 - 6.9 5.9 21.8 10 5.4 21.8 1.3 1 0 0 1 1 1 0 FAM76 protein HSP70 PF00012.20 CDJ50590.1 - 1.1e-10 40.4 24.8 1.1e-09 37.0 0.0 3.4 3 1 1 4 4 4 2 Hsp70 protein TPR_12 PF13424.6 CDJ50590.1 - 0.00016 21.9 1.4 0.00016 21.9 1.4 4.1 3 2 1 4 4 3 1 Tetratricopeptide repeat Macoilin PF09726.9 CDJ50590.1 - 0.0011 17.6 23.6 0.0018 16.9 23.6 1.3 1 0 0 1 1 1 1 Macoilin family AF-4 PF05110.13 CDJ50590.1 - 0.0026 16.0 17.2 0.0036 15.5 17.2 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein DNA_III_psi PF03603.13 CDJ50590.1 - 0.0035 17.6 4.4 0.0068 16.7 3.8 1.8 1 1 0 1 1 1 1 DNA polymerase III psi subunit DUF2895 PF11444.8 CDJ50590.1 - 0.037 13.4 0.8 0.069 12.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) RAP1 PF07218.11 CDJ50590.1 - 0.15 10.3 11.1 0.0081 14.5 4.9 1.8 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) TFIIA PF03153.13 CDJ50590.1 - 0.49 10.3 19.3 0.63 10.0 19.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.22 CDJ50590.1 - 0.73 8.5 3.4 0.98 8.1 3.4 1.1 1 0 0 1 1 1 0 Cytochrome P450 FAM199X PF15814.5 CDJ50590.1 - 2 7.4 14.4 11 4.9 14.7 1.9 2 0 0 2 2 2 0 Protein family FAM199X GRIM-19 PF06212.12 CDJ50590.1 - 4.7 7.2 7.2 3.6 7.5 0.1 3.1 2 1 2 4 4 4 0 GRIM-19 protein HSP70 PF00012.20 CDJ50592.1 - 0.00012 20.5 0.1 0.00012 20.5 0.1 1.5 2 0 0 2 2 2 1 Hsp70 protein DUF2722 PF10846.8 CDJ50592.1 - 0.0069 15.4 7.7 0.0069 15.4 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ50592.1 - 0.01 15.4 11.9 0.01 15.4 11.9 1.1 1 0 0 1 1 1 0 Spt20 family MAM33 PF02330.16 CDJ50592.1 - 0.038 13.9 0.3 0.038 13.9 0.3 1.0 1 0 0 1 1 1 0 Mitochondrial glycoprotein TFIIA PF03153.13 CDJ50592.1 - 0.054 13.5 8.5 0.055 13.5 8.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ50592.1 - 0.26 10.4 4.6 0.27 10.3 4.6 1.0 1 0 0 1 1 1 0 Drosophila roughex protein Protamine_P2 PF00841.19 CDJ50592.1 - 3.2 8.3 10.5 4.7 7.8 10.5 1.2 1 0 0 1 1 1 0 Sperm histone P2 DUF2722 PF10846.8 CDJ50593.1 - 0.0011 18.1 16.7 0.0039 16.2 8.4 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) DUF3408 PF11888.8 CDJ50593.1 - 0.0013 18.8 6.0 0.17 12.0 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3408) DUF702 PF05142.12 CDJ50593.1 - 0.0035 17.8 7.7 0.22 12.0 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF702) MCD PF05292.11 CDJ50593.1 - 0.017 14.7 3.2 0.51 9.9 0.1 2.1 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain Spt20 PF12090.8 CDJ50593.1 - 0.031 13.9 29.4 0.03 14.0 15.7 2.1 2 0 0 2 2 2 0 Spt20 family Connexin PF00029.19 CDJ50593.1 - 0.034 13.9 3.0 0.051 13.3 0.4 1.9 2 0 0 2 2 2 0 Connexin Med15 PF09606.10 CDJ50593.1 - 0.07 11.8 20.6 0.047 12.4 10.3 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MRI PF15325.6 CDJ50593.1 - 0.071 14.2 0.5 0.81 10.8 0.1 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection DUF4834 PF16118.5 CDJ50593.1 - 0.14 13.1 10.0 0.22 12.5 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EPL1 PF10513.9 CDJ50593.1 - 0.15 12.5 6.6 0.41 11.0 1.7 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like NPL PF17800.1 CDJ50593.1 - 0.23 12.0 5.8 1.4 9.5 0.5 2.4 2 0 0 2 2 2 0 Nucleoplasmin-like domain eIF_4EBP PF05456.11 CDJ50593.1 - 0.29 11.1 7.0 0.2 11.6 1.7 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) FYDLN_acid PF09538.10 CDJ50593.1 - 0.32 11.7 3.1 8.8 7.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Fes1 PF08609.10 CDJ50593.1 - 0.43 11.5 6.8 0.38 11.6 0.9 2.3 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 DUF775 PF05603.12 CDJ50593.1 - 0.53 9.8 10.4 3.7 7.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) CPSF100_C PF13299.6 CDJ50593.1 - 0.6 10.3 6.5 0.96 9.6 0.9 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal G0-G1_switch_2 PF15103.6 CDJ50593.1 - 0.66 10.4 9.1 1.7 9.1 1.8 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Caudo_TAP PF02413.17 CDJ50593.1 - 0.77 9.9 13.7 1.5 9.0 2.6 2.4 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK GDE_N PF12439.8 CDJ50593.1 - 0.92 8.9 7.2 7.3 6.0 0.2 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal TERB2 PF15101.6 CDJ50593.1 - 1.1 9.3 12.3 1.4 8.9 5.9 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 RskA PF10099.9 CDJ50593.1 - 1.3 9.3 8.2 3.3 8.0 0.8 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA BRF1 PF07741.13 CDJ50593.1 - 1.5 9.2 9.9 0.24 11.7 2.8 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF3371 PF11851.8 CDJ50593.1 - 1.8 9.7 11.7 1.4 10.0 4.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) CIAPIN1 PF05093.13 CDJ50593.1 - 1.9 9.0 6.1 8.4 7.0 0.7 2.3 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Ketoacyl-synt_2 PF13723.6 CDJ50593.1 - 2.2 7.9 12.7 3.1 7.4 3.9 2.5 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain U1snRNP70_N PF12220.8 CDJ50593.1 - 2.2 9.0 11.5 0.39 11.4 4.3 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FliP PF00813.20 CDJ50593.1 - 2.3 8.1 3.6 5.5 6.8 0.3 2.1 2 0 0 2 2 2 0 FliP family FTZ PF03867.14 CDJ50593.1 - 3.7 7.0 9.6 1.7 8.1 1.1 2.2 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region DUF1764 PF08576.10 CDJ50593.1 - 4.5 8.2 8.4 3 8.8 2.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) FAM150 PF15129.6 CDJ50593.1 - 6.3 7.0 11.1 1.2 9.3 3.5 2.4 2 0 0 2 2 2 0 FAM150 family AIF_C PF14721.6 CDJ50593.1 - 7.3 7.0 6.8 4.4 7.7 1.2 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Rpp20 PF12328.8 CDJ50593.1 - 8.1 6.4 10.4 1.2 9.1 3.7 2.1 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P RNA_capsid PF03035.14 CDJ50593.1 - 9.4 6.2 15.2 0.54 10.2 2.5 2.1 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein Nkap_C PF06047.11 CDJ50594.1 - 9.7e-24 83.4 0.1 9.7e-24 83.4 0.1 7.4 7 1 0 7 7 7 1 NF-kappa-B-activating protein C-terminal domain SR-25 PF10500.9 CDJ50594.1 - 4e-08 33.1 20.7 4e-08 33.1 20.7 9.8 5 3 4 9 9 9 3 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 CDJ50594.1 - 2.4e-07 29.3 5.7 2.4e-07 29.3 5.7 8.8 3 3 3 7 7 7 1 Sporozoite P67 surface antigen Pex14_N PF04695.13 CDJ50594.1 - 0.0027 18.4 8.5 0.0027 18.4 8.5 9.9 6 3 1 7 7 7 2 Peroxisomal membrane anchor protein (Pex14p) conserved region E1-E2_ATPase PF00122.20 CDJ50595.1 - 5.2e-27 94.5 0.1 5.6e-27 94.4 0.1 1.0 1 0 0 1 1 1 1 E1-E2 ATPase NPR3 PF03666.13 CDJ50597.1 - 0.0067 15.3 12.5 0.0096 14.8 12.5 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 CDJ50597.1 - 0.0099 14.2 16.9 0.012 13.9 16.9 1.1 1 0 0 1 1 1 1 CDC45-like protein Presenilin PF01080.17 CDJ50597.1 - 0.015 14.1 18.4 0.019 13.8 18.4 1.1 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 CDJ50597.1 - 0.029 13.8 17.1 0.043 13.2 17.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SAPS PF04499.15 CDJ50597.1 - 0.053 12.3 8.9 0.067 12.0 8.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 CDJ50597.1 - 0.15 11.2 6.4 0.19 10.9 6.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PNISR PF15996.5 CDJ50597.1 - 0.17 12.2 24.7 0.26 11.5 24.7 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR PA26 PF04636.13 CDJ50597.1 - 0.19 10.6 16.4 0.25 10.2 16.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SLC12 PF03522.15 CDJ50597.1 - 0.27 10.2 16.3 0.36 9.8 16.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 AUX_IAA PF02309.16 CDJ50597.1 - 0.54 10.1 9.7 0.74 9.6 9.7 1.2 1 0 0 1 1 1 0 AUX/IAA family Spore_coat_CotO PF14153.6 CDJ50597.1 - 0.59 10.0 29.3 0.95 9.4 29.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Tim54 PF11711.8 CDJ50597.1 - 0.85 8.3 18.1 1.3 7.7 18.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nucleo_P87 PF07267.11 CDJ50597.1 - 1.1 8.1 15.3 1.4 7.7 15.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC27 PF09507.10 CDJ50597.1 - 1.1 8.6 25.6 0.051 13.0 17.1 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF2151 PF10221.9 CDJ50597.1 - 1.3 7.5 9.6 1.6 7.2 9.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4175 PF13779.6 CDJ50597.1 - 1.3 6.8 38.2 2.1 6.1 38.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Astro_capsid_p PF12226.8 CDJ50597.1 - 1.4 8.0 14.4 2 7.5 14.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Gti1_Pac2 PF09729.9 CDJ50597.1 - 1.4 9.0 15.6 2.4 8.2 15.6 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family TFIIIC_delta PF12657.7 CDJ50597.1 - 1.5 8.7 9.0 2.6 7.9 9.0 1.3 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term MDM10 PF12519.8 CDJ50597.1 - 1.5 7.6 14.9 2.1 7.1 14.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Hid1 PF12722.7 CDJ50597.1 - 1.7 6.6 20.2 2.3 6.3 20.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.9 CDJ50597.1 - 1.8 6.8 34.5 2.2 6.4 34.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ50597.1 - 1.8 8.3 25.4 2.9 7.6 25.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Otopetrin PF03189.13 CDJ50597.1 - 2.7 6.7 4.4 3.4 6.4 4.4 1.1 1 0 0 1 1 1 0 Otopetrin LAP1C PF05609.12 CDJ50597.1 - 3.2 6.7 19.4 3.9 6.4 19.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Neur_chan_memb PF02932.16 CDJ50597.1 - 3.6 7.6 13.9 5 7.1 13.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FUSC PF04632.12 CDJ50597.1 - 5.3 5.5 17.0 7.2 5.0 17.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF908 PF06012.12 CDJ50597.1 - 6.2 6.1 13.7 8.7 5.6 13.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF913 PF06025.12 CDJ50597.1 - 7.8 5.4 14.5 11 4.9 14.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PPP4R2 PF09184.11 CDJ50597.1 - 8.2 5.9 20.2 12 5.4 20.2 1.1 1 0 0 1 1 1 0 PPP4R2 Sporozoite_P67 PF05642.11 CDJ50597.1 - 8.3 4.4 10.4 16 3.4 10.4 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PP2C PF00481.21 CDJ50599.1 - 2e-26 93.2 0.0 2e-26 93.2 0.0 3.0 2 1 1 3 3 3 1 Protein phosphatase 2C PIG-S PF10510.9 CDJ50601.1 - 0.0054 15.6 14.7 0.0064 15.4 14.7 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein SOBP PF15279.6 CDJ50601.1 - 0.03 14.9 29.9 0.033 14.8 29.9 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Dapper PF15268.6 CDJ50601.1 - 0.1 11.4 24.1 0.12 11.2 24.1 1.1 1 0 0 1 1 1 0 Dapper DDHD PF02862.17 CDJ50601.1 - 0.11 12.7 10.6 0.13 12.4 10.6 1.3 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 CDJ50601.1 - 0.17 9.8 17.3 0.19 9.6 17.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF572 PF04502.13 CDJ50601.1 - 0.17 11.5 13.5 0.19 11.3 13.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CRT10 PF08728.10 CDJ50601.1 - 0.26 9.4 8.2 0.31 9.2 8.2 1.0 1 0 0 1 1 1 0 CRT10 DUF3523 PF12037.8 CDJ50601.1 - 0.4 10.0 37.7 0.57 9.5 37.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) AAA_11 PF13086.6 CDJ50601.1 - 0.66 9.7 25.9 0.94 9.2 25.9 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 CDJ50601.1 - 0.74 9.3 29.1 1.1 8.7 29.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GREB1 PF15782.5 CDJ50601.1 - 0.76 6.8 23.6 0.79 6.8 23.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BPL_N PF09825.9 CDJ50601.1 - 2.2 7.3 11.6 2.7 7.0 11.6 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal MMR1 PF08505.10 CDJ50601.1 - 2.2 8.5 23.5 3.3 7.9 23.5 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein ALMT PF11744.8 CDJ50601.1 - 2.7 6.7 16.2 3.4 6.4 16.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ50601.1 - 2.8 6.1 43.5 3.1 5.9 43.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 CDJ50601.1 - 2.8 6.8 22.3 4.6 6.1 22.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Phage_GPO PF05929.11 CDJ50601.1 - 3.4 7.2 25.4 4.6 6.8 25.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Presenilin PF01080.17 CDJ50601.1 - 3.9 6.2 25.2 5.6 5.6 25.2 1.3 1 0 0 1 1 1 0 Presenilin DUF966 PF06136.13 CDJ50601.1 - 5 6.8 17.4 5.9 6.5 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FapA PF03961.13 CDJ50601.1 - 5.7 5.4 19.6 7.3 5.1 19.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Membralin PF09746.9 CDJ50601.1 - 6.7 5.6 15.3 8.6 5.3 15.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein SLC12 PF03522.15 CDJ50601.1 - 7.3 5.5 22.8 9 5.2 22.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.11 CDJ50601.1 - 8.7 5.7 18.4 13 5.2 18.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Asp-B-Hydro_N PF05279.11 CDJ50601.1 - 9.5 6.2 13.8 12 5.9 13.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Lin-8 PF03353.15 CDJ50601.1 - 9.8 5.6 26.1 15 5.1 26.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RskA PF10099.9 CDJ50602.1 - 0.00068 20.0 10.9 0.00088 19.6 10.9 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA FHIPEP PF00771.20 CDJ50602.1 - 0.15 10.5 2.6 0.18 10.3 2.6 1.0 1 0 0 1 1 1 0 FHIPEP family TFIIA PF03153.13 CDJ50602.1 - 0.19 11.7 15.5 0.22 11.5 15.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ50602.1 - 1.4 9.5 10.3 0.25 12.0 6.2 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4366 PF14283.6 CDJ50603.1 - 3.8 7.5 11.4 1 9.4 1.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4366) Lactamase_B_2 PF12706.7 CDJ50604.1 - 1.6 8.2 9.3 0.34 10.4 3.5 3.0 2 0 0 2 2 2 0 Beta-lactamase superfamily domain ACDC PF14733.6 CDJ50605.1 - 1.3e-14 54.3 0.0 1.3e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 AP2-coincident C-terminal Spt20 PF12090.8 CDJ50605.1 - 0.099 12.2 20.3 0.22 11.1 20.3 1.6 1 0 0 1 1 1 0 Spt20 family Cellulose_synt PF03552.14 CDJ50606.1 - 1.8 7.0 7.4 1.9 6.9 7.4 1.2 1 0 0 1 1 1 0 Cellulose synthase ASC PF00858.24 CDJ50606.1 - 2.4 7.0 10.7 3 6.7 10.7 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF966 PF06136.13 CDJ50606.1 - 4.3 7.0 33.6 5.3 6.7 33.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CCSAP PF15748.5 CDJ50606.1 - 4.8 7.3 35.2 7.7 6.6 35.2 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated IMUP PF15761.5 CDJ50607.1 - 3.6 8.3 13.9 0.62 10.8 8.8 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF3522 PF12036.8 CDJ50608.1 - 7.1e-05 23.2 0.6 7.1e-05 23.2 0.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3522) RskA PF10099.9 CDJ50608.1 - 0.0099 16.2 1.0 0.25 11.6 0.0 3.0 2 1 0 2 2 2 1 Anti-sigma-K factor rskA Rpp20 PF12328.8 CDJ50608.1 - 0.025 14.6 0.4 0.025 14.6 0.4 2.4 2 1 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Trypan_PARP PF05887.11 CDJ50608.1 - 0.072 13.1 5.2 0.27 11.2 5.2 2.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NPR3 PF03666.13 CDJ50608.1 - 0.23 10.2 8.1 16 4.2 8.9 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Ctr PF04145.15 CDJ50608.1 - 2.2 8.9 5.5 3.3 8.3 0.5 2.5 2 1 0 2 2 2 0 Ctr copper transporter family Neur_chan_memb PF02932.16 CDJ50608.1 - 3.5 7.6 9.1 1.2e+02 2.6 9.1 2.2 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4818 PF16089.5 CDJ50608.1 - 4.8 7.7 8.6 1.8 9.1 4.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4818) Zip PF02535.22 CDJ50608.1 - 8.8 5.4 10.6 24 4.0 0.0 3.2 3 0 0 3 3 3 0 ZIP Zinc transporter Phage_lysis PF03245.13 CDJ50609.1 - 0.042 14.0 1.0 0.1 12.7 1.0 1.6 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Sporozoite_P67 PF05642.11 CDJ50609.1 - 0.22 9.6 2.4 0.24 9.4 2.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pap_E4 PF02711.14 CDJ50609.1 - 0.54 11.3 8.3 0.28 12.2 1.1 3.1 3 1 0 3 3 3 0 E4 protein DUF4888 PF16229.5 CDJ50610.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4888) PilM PF07419.12 CDJ50611.1 - 0.18 12.0 0.4 0.18 12.0 0.4 4.0 5 0 0 5 5 5 0 PilM FSA_C PF10479.9 CDJ50611.1 - 0.2 9.8 4.5 0.29 9.2 4.5 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ebp2 PF05890.12 CDJ50613.1 - 0.00031 20.4 0.0 0.00042 19.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 TauE PF01925.19 CDJ50618.1 - 2.7e-16 59.9 46.4 2e-10 40.7 19.9 3.9 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE PAN_4 PF14295.6 CDJ50619.1 - 2.3e-43 145.8 61.5 2.2e-05 24.3 0.2 11.9 11 0 0 11 11 11 10 PAN domain PAN_1 PF00024.26 CDJ50619.1 - 2.8e-39 132.9 49.2 1.2e-05 25.1 0.0 11.6 11 1 1 12 12 12 9 PAN domain DUF2722 PF10846.8 CDJ50619.1 - 0.014 14.4 1.6 0.019 13.9 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MANEC PF07502.14 CDJ50619.1 - 0.084 13.2 0.1 0.084 13.2 0.1 8.5 8 1 1 9 9 9 0 MANEC domain SUIM_assoc PF16619.5 CDJ50619.1 - 0.16 12.0 8.4 0.39 10.8 8.4 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ50619.1 - 0.35 10.8 8.1 0.59 10.1 8.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ50619.1 - 1.6 8.3 13.0 2.5 7.6 13.0 1.2 1 0 0 1 1 1 0 Spt20 family TSP_1 PF00090.19 CDJ50620.1 - 4.5e-06 26.8 1.6 4.5e-06 26.8 1.6 3.8 4 1 0 4 4 4 1 Thrombospondin type 1 domain Exonuc_VII_L PF02601.15 CDJ50620.1 - 0.0055 16.3 5.7 0.0055 16.3 5.7 2.0 2 0 0 2 2 2 1 Exonuclease VII, large subunit DUF3405 PF11885.8 CDJ50620.1 - 0.029 13.0 7.2 0.028 13.1 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3405) Trp_oprn_chp PF09534.10 CDJ50620.1 - 6 6.6 45.3 10 5.8 0.1 3.6 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) WD40 PF00400.32 CDJ50621.1 - 7.8e-07 29.7 0.0 0.035 15.0 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ50621.1 - 0.00024 21.4 0.0 0.4 11.0 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Dehydrin PF00257.19 CDJ50621.1 - 0.025 15.1 8.9 0.12 12.9 5.5 2.2 2 0 0 2 2 2 0 Dehydrin CAF1 PF04857.20 CDJ50622.1 - 6.2e-43 147.2 2.5 6.2e-43 147.2 2.5 3.2 3 0 0 3 3 3 1 CAF1 family ribonuclease TFIIA PF03153.13 CDJ50622.1 - 0.002 18.2 134.4 0.0055 16.8 44.3 3.3 3 0 0 3 3 3 3 Transcription factor IIA, alpha/beta subunit DUF3853 PF12964.7 CDJ50622.1 - 0.031 14.5 0.0 0.031 14.5 0.0 5.0 3 2 2 5 5 5 0 Protein of unknown function (DUF3853) IL17R_D_N PF16742.5 CDJ50623.1 - 1.2 9.3 2.8 1.8 8.7 0.0 2.5 3 0 0 3 3 3 0 N-terminus of interleukin 17 receptor D MMR1 PF08505.10 CDJ50624.1 - 0.012 16.0 11.3 0.012 15.9 11.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RskA PF10099.9 CDJ50624.1 - 0.014 15.7 10.6 0.014 15.7 10.6 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ50624.1 - 0.016 14.8 24.4 0.019 14.6 24.4 1.2 1 0 0 1 1 1 0 Spt20 family EPL1 PF10513.9 CDJ50624.1 - 0.05 14.0 7.0 0.055 13.8 7.0 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Peptidase_S49_N PF08496.10 CDJ50624.1 - 0.059 13.4 6.3 0.075 13.1 6.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MAP65_ASE1 PF03999.12 CDJ50624.1 - 0.061 12.0 10.1 0.074 11.7 10.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF2722 PF10846.8 CDJ50624.1 - 0.1 11.5 23.6 0.15 11.0 23.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4770 PF15994.5 CDJ50624.1 - 0.11 12.7 8.4 0.14 12.4 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) TERB2 PF15101.6 CDJ50624.1 - 0.14 12.2 13.8 0.17 11.9 13.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Lin-8 PF03353.15 CDJ50624.1 - 0.26 10.8 9.5 0.26 10.8 9.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF719 PF05334.13 CDJ50624.1 - 0.32 11.2 8.5 0.51 10.5 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Band_3_cyto PF07565.13 CDJ50624.1 - 0.34 10.7 6.1 0.36 10.6 6.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Miga PF10265.9 CDJ50624.1 - 0.35 9.8 9.1 0.4 9.6 9.1 1.0 1 0 0 1 1 1 0 Mitoguardin Connexin PF00029.19 CDJ50624.1 - 0.48 10.1 2.9 0.53 10.0 2.9 1.1 1 0 0 1 1 1 0 Connexin LptF_LptG PF03739.14 CDJ50624.1 - 0.49 9.2 2.1 0.52 9.1 2.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Presenilin PF01080.17 CDJ50624.1 - 0.6 8.8 9.1 0.58 8.9 9.1 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 CDJ50624.1 - 0.84 8.4 6.0 0.84 8.4 6.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1207 PF06727.11 CDJ50624.1 - 1 8.2 4.2 1.2 8.0 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) Ctr PF04145.15 CDJ50624.1 - 1.2 9.8 4.0 1.3 9.6 4.0 1.3 1 0 0 1 1 1 0 Ctr copper transporter family TFIIA PF03153.13 CDJ50624.1 - 1.2 9.0 35.0 1.6 8.6 35.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ50624.1 - 1.4 7.8 10.7 1.5 7.7 10.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 CDJ50624.1 - 1.5 7.8 4.4 1.5 7.8 4.4 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4834 PF16118.5 CDJ50624.1 - 1.6 9.8 11.3 2.1 9.3 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4366 PF14283.6 CDJ50624.1 - 2 8.5 7.3 0.37 10.8 3.4 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4366) Neur_chan_memb PF02932.16 CDJ50624.1 - 2.2 8.2 7.9 2.4 8.2 7.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 CDJ50624.1 - 2.5 5.9 8.0 2.8 5.7 8.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3464 PF11947.8 CDJ50624.1 - 3.9 7.2 8.1 5.5 6.7 8.1 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Suf PF05843.14 CDJ50624.1 - 4 7.3 13.0 4.2 7.3 13.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_DNAp_acc PF04929.12 CDJ50624.1 - 4.6 6.1 12.6 5.7 5.8 12.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MAS20 PF02064.15 CDJ50624.1 - 5 7.2 15.2 0.49 10.5 9.7 2.0 2 0 0 2 2 2 0 MAS20 protein import receptor YfhO PF09586.10 CDJ50624.1 - 9.3 4.3 7.4 9.3 4.3 7.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Roughex PF06020.11 CDJ50624.1 - 9.4 5.2 11.2 11 5.0 11.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PsaL PF02605.15 CDJ50625.1 - 0.12 12.0 1.0 0.25 11.0 0.1 1.9 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI PAT1 PF09770.9 CDJ50625.1 - 2.2 6.5 22.7 2.5 6.3 22.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GET2 PF08690.10 CDJ50625.1 - 2.6 7.6 20.0 1.7 8.3 15.6 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 X PF00739.19 CDJ50625.1 - 4 7.6 5.6 5.3 7.2 0.2 2.2 2 0 0 2 2 2 0 Trans-activation protein X Nitroreductase PF00881.24 CDJ50625.1 - 6.7 6.7 11.3 1.5 8.8 5.1 2.2 1 1 0 2 2 2 0 Nitroreductase family DUF4179 PF13786.6 CDJ50626.1 - 0.0062 17.0 3.5 5.4 7.6 0.3 5.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4179) DUF2722 PF10846.8 CDJ50627.1 - 0.0028 16.7 0.8 0.0028 16.7 0.8 4.1 3 1 0 3 3 3 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ50627.1 - 0.0033 17.1 4.7 0.0033 17.1 4.7 4.0 3 1 0 4 4 4 2 Spt20 family DUF4834 PF16118.5 CDJ50627.1 - 0.51 11.3 31.9 1.2 10.1 1.7 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) TPR_1 PF00515.28 CDJ50627.1 - 0.75 9.7 6.8 6.2 6.8 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1980 PF09323.10 CDJ50627.1 - 0.78 9.6 12.7 0.97 9.3 0.8 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1980) EphA2_TM PF14575.6 CDJ50627.1 - 1.2 10.1 13.6 4.9 8.1 0.0 3.8 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain TPR_2 PF07719.17 CDJ50627.1 - 1.7 9.0 17.8 0.63 10.3 0.6 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat CLN3 PF02487.17 CDJ50627.1 - 1.7 7.6 13.4 8.7 5.3 2.0 3.4 3 0 0 3 3 3 0 CLN3 protein Connexin PF00029.19 CDJ50627.1 - 3.4 7.3 14.0 1.1 8.9 1.4 3.1 3 0 0 3 3 3 0 Connexin Thg1C PF14413.6 CDJ50627.1 - 6.6 6.9 12.3 7.5 6.7 0.2 3.5 3 0 0 3 3 3 0 Thg1 C terminal domain Abhydrolase_9_N PF15420.6 CDJ50628.1 - 7.7 6.5 14.2 7.5 6.5 5.1 3.9 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus TFIIA PF03153.13 CDJ50629.1 - 0.025 14.6 50.9 0.036 14.1 50.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 CDJ50629.1 - 0.12 10.8 0.4 0.14 10.5 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NEMP PF10225.9 CDJ50629.1 - 1.1 8.8 3.6 1.8 8.1 3.6 1.4 1 0 0 1 1 1 0 NEMP family SpoIIP PF07454.11 CDJ50629.1 - 1.2 8.6 10.8 2.2 7.7 10.8 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PAT1 PF09770.9 CDJ50629.1 - 1.3 7.2 31.5 1.7 6.8 31.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PC_rep PF01851.22 CDJ50630.1 - 1.2e-07 31.8 6.9 0.24 11.9 0.1 5.3 5 0 0 5 5 5 3 Proteasome/cyclosome repeat SR-25 PF10500.9 CDJ50630.1 - 1.3e-07 31.5 19.7 4.1e-06 26.6 2.6 20.7 17 3 1 19 19 19 7 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ50630.1 - 6e-06 25.5 4.6 6e-06 25.5 4.6 18.9 13 7 5 18 18 18 3 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ50630.1 - 0.19 12.0 0.0 0.081 13.2 16.3 25.9 9 7 7 18 18 18 0 Anti-sigma-K factor rskA Glyco_hydro_9 PF00759.19 CDJ50632.1 - 0.012 15.1 1.1 0.012 15.1 1.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 T2SSM PF04612.12 CDJ50632.1 - 0.058 13.5 15.9 0.057 13.5 15.9 1.0 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M RskA PF10099.9 CDJ50632.1 - 0.2 11.9 14.3 0.64 10.3 1.0 1.9 1 1 1 2 2 2 0 Anti-sigma-K factor rskA CLN3 PF02487.17 CDJ50632.1 - 0.37 9.8 3.7 0.38 9.8 3.7 1.0 1 0 0 1 1 1 0 CLN3 protein V_ATPase_I PF01496.19 CDJ50632.1 - 0.65 7.9 5.5 0.62 7.9 5.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC53 PF10152.9 CDJ50632.1 - 0.8 10.1 9.7 0.98 9.8 9.7 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2722 PF10846.8 CDJ50632.1 - 0.94 8.4 17.5 1 8.2 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ50632.1 - 0.95 9.0 24.6 1.1 8.8 24.6 1.1 1 0 0 1 1 1 0 Spt20 family DUF3138 PF11336.8 CDJ50632.1 - 1.3 7.6 10.0 1.2 7.6 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Neur_chan_memb PF02932.16 CDJ50632.1 - 3.8 7.5 6.2 3.8 7.5 6.2 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ50632.1 - 6.1 6.7 22.5 6.7 6.6 22.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ50632.1 - 6.5 5.4 10.9 6.8 5.3 10.9 1.0 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 CDJ50632.1 - 7.8 6.5 11.8 8.6 6.4 11.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ50634.1 - 0.006 16.2 14.6 0.0063 16.1 14.6 1.1 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ50634.1 - 0.019 15.0 16.9 0.022 14.8 16.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GRP PF07172.11 CDJ50634.1 - 0.028 15.1 1.7 0.037 14.7 1.7 1.2 1 0 0 1 1 1 0 Glycine rich protein family V_ATPase_I PF01496.19 CDJ50634.1 - 0.078 10.9 2.5 0.089 10.7 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 CDJ50634.1 - 0.098 11.7 0.4 0.11 11.6 0.4 1.0 1 0 0 1 1 1 0 CLN3 protein DUF2722 PF10846.8 CDJ50634.1 - 0.19 10.6 14.1 0.24 10.3 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 CDJ50634.1 - 0.21 10.5 8.7 0.22 10.4 8.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 CDJ50634.1 - 0.46 10.2 1.9 0.52 10.0 1.9 1.1 1 0 0 1 1 1 0 Connexin GREB1 PF15782.5 CDJ50634.1 - 2.3 5.2 6.4 2.6 5.1 6.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NPR3 PF03666.13 CDJ50634.1 - 2.8 6.6 7.1 3 6.5 7.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ50634.1 - 5 5.8 10.8 5.2 5.7 10.8 1.0 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ50634.1 - 5.1 5.7 6.7 5.3 5.6 6.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF572 PF04502.13 CDJ50635.1 - 0.9 9.1 21.7 1 8.9 21.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) ABC_tran PF00005.27 CDJ50639.1 - 4.6e-27 95.2 0.0 4.6e-27 95.2 0.0 3.3 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 CDJ50639.1 - 5.7e-05 23.1 0.4 0.042 13.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RskA PF10099.9 CDJ50639.1 - 7.7e-05 23.1 0.0 7.7e-05 23.1 0.0 5.0 2 2 1 3 3 1 1 Anti-sigma-K factor rskA RR_TM4-6 PF06459.12 CDJ50639.1 - 0.00012 22.1 44.5 0.02 14.7 16.4 2.1 2 0 0 2 2 2 2 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ50639.1 - 0.014 14.2 48.6 0.031 13.0 17.1 2.2 2 0 0 2 2 2 0 Presenilin PRK PF00485.18 CDJ50639.1 - 0.028 14.2 2.9 0.037 13.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Neur_chan_memb PF02932.16 CDJ50639.1 - 0.031 14.3 38.0 0.33 11.0 13.5 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region AAA_18 PF13238.6 CDJ50639.1 - 0.046 14.3 0.1 0.046 14.3 0.1 3.4 3 2 0 3 3 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ50639.1 - 0.049 13.5 0.3 0.049 13.5 0.3 3.0 3 1 0 3 3 2 0 RsgA GTPase AAA PF00004.29 CDJ50639.1 - 0.06 13.8 0.1 0.06 13.8 0.1 3.4 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CDJ50639.1 - 0.064 13.0 44.0 0.12 12.2 13.7 3.4 3 0 0 3 3 3 0 AAA domain Apt1 PF10351.9 CDJ50639.1 - 0.17 10.7 31.4 0.0096 14.8 12.5 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF2052 PF09747.9 CDJ50639.1 - 0.19 11.9 53.8 1.3 9.1 20.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF913 PF06025.12 CDJ50639.1 - 0.6 9.0 26.4 0.47 9.4 6.6 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) PAT1 PF09770.9 CDJ50639.1 - 1.1 7.5 67.4 0.62 8.3 27.2 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF3807 PF12720.7 CDJ50639.1 - 1.5 9.1 55.7 1 9.6 23.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Pox_Ag35 PF03286.14 CDJ50639.1 - 1.5 8.5 34.0 0.42 10.4 10.1 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PPL5 PF18168.1 CDJ50639.1 - 2.2 7.5 31.8 8.4 5.6 9.4 3.1 2 1 0 2 2 2 0 Prim-pol family 5 Exonuc_VII_L PF02601.15 CDJ50639.1 - 2.9 7.4 43.7 0.17 11.4 14.8 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF572 PF04502.13 CDJ50639.1 - 2.9 7.4 40.2 1.4 8.5 13.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) MobB PF03205.14 CDJ50639.1 - 3.1 7.7 5.2 0.41 10.5 0.2 2.2 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B LTV PF04180.14 CDJ50639.1 - 3.6 7.2 38.5 0.88 9.2 10.4 2.1 2 0 0 2 2 2 0 Low temperature viability protein SMYLE_N PF18615.1 CDJ50639.1 - 3.7 7.0 36.3 0.42 10.1 13.0 2.2 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SLC12 PF03522.15 CDJ50639.1 - 4.7 6.1 47.7 1.6 7.7 17.8 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Endostatin PF06482.11 CDJ50639.1 - 8.1 5.8 40.3 5 6.5 16.6 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Caldesmon PF02029.15 CDJ50640.1 - 0.023 13.5 32.3 0.038 12.8 32.3 1.3 1 0 0 1 1 1 0 Caldesmon AF-4 PF05110.13 CDJ50640.1 - 4.1 5.4 41.5 5.9 4.9 41.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDK5_activator PF03261.15 CDJ50641.1 - 4.9 6.6 25.8 6.5 6.2 25.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TFIIA PF03153.13 CDJ50642.1 - 0.03 14.3 22.3 0.045 13.7 22.3 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VanY PF02557.17 CDJ50642.1 - 0.68 9.7 6.4 1.4 8.7 6.4 1.6 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Spt20 PF12090.8 CDJ50642.1 - 2.3 7.8 13.2 1.3 8.6 11.0 1.6 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ50643.1 - 2.1e-05 24.3 11.6 2.1e-05 24.3 11.6 7.2 5 2 1 6 6 6 2 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 CDJ50643.1 - 6.3 5.1 12.2 3.5 5.9 0.9 2.4 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) BRF1 PF07741.13 CDJ50644.1 - 7.2e-14 52.0 1.2 7.2e-14 52.0 1.2 3.8 4 0 0 4 4 4 2 Brf1-like TBP-binding domain TFIIB PF00382.19 CDJ50644.1 - 2.5e-06 27.4 0.0 2.7e-05 24.1 0.0 3.0 1 0 0 1 1 1 1 Transcription factor TFIIB repeat DUF2722 PF10846.8 CDJ50644.1 - 0.00049 19.2 7.0 0.00049 19.2 7.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) XRCC4 PF06632.12 CDJ50644.1 - 0.1 11.4 18.8 0.16 10.8 3.4 3.1 3 0 0 3 3 3 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Neur_chan_memb PF02932.16 CDJ50644.1 - 0.12 12.4 3.8 0.16 12.0 0.2 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.13 CDJ50645.1 - 0.036 14.7 19.6 0.043 14.5 19.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NST1 PF13945.6 CDJ50645.1 - 0.088 12.9 16.2 0.13 12.3 16.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator TFIIA PF03153.13 CDJ50645.1 - 0.09 12.8 37.6 0.1 12.6 37.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ50645.1 - 0.17 9.9 23.2 0.19 9.8 23.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PAT1 PF09770.9 CDJ50645.1 - 0.2 9.9 26.2 0.21 9.8 26.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.15 CDJ50645.1 - 0.38 10.3 16.4 0.39 10.2 16.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Presenilin PF01080.17 CDJ50645.1 - 0.92 8.2 15.1 1.1 8.0 15.1 1.1 1 0 0 1 1 1 0 Presenilin CSG2 PF16965.5 CDJ50645.1 - 1.1 8.1 6.1 1.3 7.9 6.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Sec62 PF03839.16 CDJ50645.1 - 1.7 8.1 9.4 2 7.8 9.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 OmpH PF03938.14 CDJ50645.1 - 1.8 8.9 29.1 2.4 8.5 29.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Zip PF02535.22 CDJ50645.1 - 2.5 7.2 13.4 3.2 6.9 13.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.16 CDJ50645.1 - 2.5 7.3 6.0 3.1 7.0 6.0 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein GREB1 PF15782.5 CDJ50645.1 - 3.2 4.8 18.2 3.5 4.6 18.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer VIT1 PF01988.19 CDJ50645.1 - 3.2 7.5 6.3 3.8 7.3 6.3 1.2 1 0 0 1 1 1 0 VIT family RR_TM4-6 PF06459.12 CDJ50645.1 - 3.7 7.3 13.5 4.8 6.9 13.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ50645.1 - 4 6.4 14.7 4.4 6.2 14.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 CDJ50645.1 - 5.1 7.1 10.8 5.8 7.0 10.8 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family PXA PF02194.15 CDJ50645.1 - 6.5 6.7 12.4 9 6.2 12.4 1.2 1 0 0 1 1 1 0 PXA domain FHIPEP PF00771.20 CDJ50645.1 - 6.6 5.1 8.8 7.6 4.9 8.8 1.0 1 0 0 1 1 1 0 FHIPEP family Kei1 PF08552.11 CDJ50645.1 - 7 6.5 9.1 11 5.8 9.1 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 ALMT PF11744.8 CDJ50645.1 - 7.4 5.3 12.2 8.5 5.1 12.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SelP_N PF04592.14 CDJ50645.1 - 7.9 5.8 27.7 12 5.3 27.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MMR1 PF08505.10 CDJ50645.1 - 8 6.7 17.2 10 6.3 17.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Hydrolase_4 PF12146.8 CDJ50646.1 - 9.5e-08 31.6 0.1 2.4e-07 30.3 0.0 1.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 TraT PF05818.12 CDJ50646.1 - 0.88 9.2 7.6 1.2 8.8 7.6 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Presenilin PF01080.17 CDJ50647.1 - 0.056 12.2 39.0 0.072 11.8 39.0 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ50647.1 - 0.095 12.7 27.2 0.13 12.2 27.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A MDFI PF15316.6 CDJ50647.1 - 0.23 11.6 26.2 0.32 11.0 26.2 1.3 1 0 0 1 1 1 0 MyoD family inhibitor SAGA-Tad1 PF12767.7 CDJ50647.1 - 0.27 10.9 27.8 0.31 10.7 27.8 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4045 PF13254.6 CDJ50647.1 - 0.67 9.5 27.3 0.8 9.3 27.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PNISR PF15996.5 CDJ50647.1 - 1.2 9.4 44.9 1.5 9.1 44.9 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR LAP1C PF05609.12 CDJ50647.1 - 4.3 6.3 35.5 5.3 6.0 35.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Zip PF02535.22 CDJ50647.1 - 4.9 6.3 23.3 7.7 5.6 23.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CAC1F_C PF16885.5 CDJ50647.1 - 5.5 6.6 23.0 6.8 6.2 23.0 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term NPR3 PF03666.13 CDJ50647.1 - 6 5.5 34.7 10 4.8 34.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ndc1_Nup PF09531.10 CDJ50647.1 - 6.8 5.2 33.1 7.1 5.2 33.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 CDJ50647.1 - 7.2 5.2 32.0 8.3 4.9 32.0 1.0 1 0 0 1 1 1 0 Hamartin protein SLC12 PF03522.15 CDJ50647.1 - 8.7 5.2 41.3 11 4.9 41.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 CDJ50647.1 - 9.1 4.9 27.8 10 4.8 27.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.12 CDJ50647.1 - 9.2 6.4 32.0 12 6.1 32.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2722 PF10846.8 CDJ50648.1 - 0.0006 18.9 13.6 0.00092 18.3 13.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Sporozoite_P67 PF05642.11 CDJ50648.1 - 0.12 10.5 17.5 0.16 10.0 17.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SLC12 PF03522.15 CDJ50648.1 - 0.67 8.9 11.9 0.79 8.7 11.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 V_ATPase_I PF01496.19 CDJ50648.1 - 0.69 7.8 6.8 0.84 7.5 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIP5K PF01504.18 CDJ50648.1 - 0.78 8.9 8.4 1.1 8.4 8.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Connexin PF00029.19 CDJ50648.1 - 2.2 8.0 6.3 3.1 7.5 6.3 1.3 1 0 0 1 1 1 0 Connexin DUF2052 PF09747.9 CDJ50648.1 - 2.5 8.2 12.3 4.2 7.4 12.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4770 PF15994.5 CDJ50648.1 - 3.8 7.7 13.9 5.7 7.1 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4834 PF16118.5 CDJ50648.1 - 4.8 8.2 14.8 1 10.3 10.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 CDJ50648.1 - 7.2 7.0 9.7 0.71 10.2 4.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) EIF4E-T PF10477.9 CDJ50649.1 - 0.012 14.5 9.2 0.014 14.2 9.2 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Tho2 PF11262.8 CDJ50649.1 - 0.027 13.7 2.8 0.038 13.2 2.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 SLC12 PF03522.15 CDJ50649.1 - 0.075 12.0 10.0 0.11 11.5 10.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 LMBR1 PF04791.16 CDJ50649.1 - 0.13 11.2 1.0 0.14 11.0 1.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein O-antigen_lig PF13425.6 CDJ50649.1 - 0.45 9.3 0.5 0.53 9.0 0.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein eIF-3_zeta PF05091.12 CDJ50649.1 - 1.2 8.0 14.1 1.5 7.7 14.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ50649.1 - 1.3 7.2 35.1 1.7 6.8 35.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 CDJ50649.1 - 1.6 8.2 19.3 0.034 13.7 11.4 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist EPL1 PF10513.9 CDJ50649.1 - 2.4 8.5 12.3 0.4 11.0 5.9 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Glyco_hydro_2 PF00703.21 CDJ50649.1 - 3.7 8.3 9.7 0.33 11.6 4.1 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 2 DUF262 PF03235.14 CDJ50650.1 - 0.56 10.3 10.8 0.69 10.0 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 SID-1_RNA_chan PF13965.6 CDJ50650.1 - 1 7.7 7.6 1.1 7.5 7.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AAA_11 PF13086.6 CDJ50650.1 - 1.4 8.6 21.9 2 8.1 21.9 1.3 1 0 0 1 1 1 0 AAA domain Nop14 PF04147.12 CDJ50650.1 - 2.7 6.1 34.7 3.7 5.7 34.7 1.1 1 0 0 1 1 1 0 Nop14-like family FAM60A PF15396.6 CDJ50650.1 - 7.3 6.5 22.7 14 5.6 22.7 1.4 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 CDJ50650.1 - 9.5 5.1 24.7 13 4.6 24.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 CDJ50651.1 - 0.00023 20.3 25.0 0.00032 19.8 5.6 2.5 2 0 0 2 2 2 2 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 CDJ50651.1 - 0.00077 19.6 9.1 0.00077 19.6 9.1 2.6 3 0 0 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region Ctr PF04145.15 CDJ50651.1 - 0.0082 16.8 4.3 0.0082 16.8 4.3 3.5 2 1 0 2 2 1 1 Ctr copper transporter family SID-1_RNA_chan PF13965.6 CDJ50651.1 - 0.011 14.2 19.6 0.18 10.2 7.4 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Afi1 PF07792.12 CDJ50651.1 - 0.013 16.0 9.7 0.013 16.0 9.7 3.1 2 1 0 2 2 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CNDH2_C PF16858.5 CDJ50651.1 - 0.015 15.2 40.8 0.025 14.5 15.4 2.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term V_ATPase_I PF01496.19 CDJ50651.1 - 0.061 11.2 47.1 0.18 9.7 16.1 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4045 PF13254.6 CDJ50651.1 - 0.067 12.8 42.7 0.067 12.8 16.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4045) Neugrin PF06413.11 CDJ50651.1 - 0.23 11.4 31.0 0.02 14.9 7.9 2.5 2 0 0 2 2 2 0 Neugrin Isy1 PF06246.12 CDJ50651.1 - 0.33 10.5 41.4 0.45 10.0 10.7 2.5 2 0 0 2 2 2 0 Isy1-like splicing family Endostatin PF06482.11 CDJ50651.1 - 0.89 9.0 43.9 0.54 9.7 18.7 3.0 3 0 0 3 3 3 0 Collagenase NC10 and Endostatin DUF2828 PF11443.8 CDJ50651.1 - 1 7.4 43.8 0.018 13.1 12.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ50651.1 - 1.9 7.2 64.4 0.7 8.6 31.5 2.6 3 0 0 3 3 3 0 Presenilin PAT1 PF09770.9 CDJ50651.1 - 2 6.6 76.9 0.065 11.5 38.2 2.4 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 Sin_N PF04801.13 CDJ50651.1 - 4.1 6.5 68.7 0.06 12.6 32.1 2.4 2 0 0 2 2 2 0 Sin-like protein conserved region BORG_CEP PF14957.6 CDJ50651.1 - 5.1 8.3 35.7 8.3 7.6 14.8 3.1 3 0 0 3 3 3 0 Cdc42 effector GAGA_bind PF06217.12 CDJ50651.1 - 5.2 7.3 39.3 1.7 8.8 17.9 2.4 3 0 0 3 3 2 0 GAGA binding protein-like family CCSAP PF15748.5 CDJ50651.1 - 5.7 7.0 58.3 0.38 10.9 23.9 3.0 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated Smg8_Smg9 PF10220.9 CDJ50651.1 - 8 4.6 42.8 0.46 8.7 19.0 2.3 2 0 0 2 2 2 0 Smg8_Smg9 OAD_gamma PF04277.13 CDJ50652.1 - 2.5 8.7 0.0 2.5 8.7 0.0 4.3 4 1 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_60s PF00428.19 CDJ50652.1 - 4.4 8.0 30.4 3.8 8.2 3.6 3.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Iso_dh PF00180.20 CDJ50653.1 - 3.7e-49 167.8 0.0 1.5e-47 162.5 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase Phosphorylase PF00343.20 CDJ50654.1 - 7.7e-298 989.7 0.0 9.2e-298 989.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase SR-25 PF10500.9 CDJ50654.1 - 0.0011 18.6 4.6 0.0018 17.9 4.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ50654.1 - 0.7 10.6 8.9 1.7 9.4 8.9 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein EGF_CA PF07645.15 CDJ50655.1 - 7.3e-220 711.0 541.8 3.8e-13 49.4 8.6 34.1 32 1 0 32 32 32 27 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ50655.1 - 4.9e-148 481.0 567.1 8e-11 41.9 15.0 34.5 33 1 1 34 34 34 29 EGF domain cEGF PF12662.7 CDJ50655.1 - 2.4e-133 433.4 291.0 1.1e-07 31.6 2.9 31.5 32 0 0 32 32 32 29 Complement Clr-like EGF-like EGF PF00008.27 CDJ50655.1 - 3.3e-61 203.1 445.2 3.9e-05 23.9 6.8 32.4 32 0 0 32 32 32 29 EGF-like domain hEGF PF12661.7 CDJ50655.1 - 3.5e-61 201.9 350.1 0.00012 22.5 3.5 33.5 31 0 0 31 31 31 26 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CDJ50655.1 - 1.1e-37 127.7 403.2 8.5e-06 25.7 6.5 32.1 31 0 0 31 31 31 21 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CDJ50655.1 - 2.4e-29 101.3 480.5 0.0031 17.8 12.6 31.8 28 2 2 30 30 30 21 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CDJ50655.1 - 1.3e-22 79.8 440.5 8.8e-05 22.7 6.6 32.6 32 1 1 33 33 33 24 Pvs28 EGF domain HTH_20 PF12840.7 CDJ50655.1 - 0.065 13.3 0.3 30 4.8 0.0 3.7 3 0 0 3 3 3 0 Helix-turn-helix domain C2 PF00168.30 CDJ50656.1 - 2.8e-35 120.7 0.0 5.1e-14 52.4 0.0 4.7 4 0 0 4 4 4 3 C2 domain Ferlin_C PF16165.5 CDJ50656.1 - 0.0027 17.7 0.0 0.0063 16.5 0.0 1.6 1 0 0 1 1 1 1 Ferlin C-terminus SF3b1 PF08920.10 CDJ50657.1 - 3.7e-26 92.0 17.8 5e-24 85.1 2.0 4.3 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 HEAT PF02985.22 CDJ50657.1 - 6.9e-08 32.1 7.0 1.3 9.4 0.1 8.0 8 0 0 8 8 8 2 HEAT repeat UME PF08064.13 CDJ50657.1 - 2.4e-05 24.2 0.8 11 6.0 0.0 5.3 5 1 0 5 5 5 2 UME (NUC010) domain HEAT_EZ PF13513.6 CDJ50657.1 - 7.9e-05 23.1 11.0 0.3 11.6 0.0 6.3 7 1 1 8 8 7 2 HEAT-like repeat Adaptin_N PF01602.20 CDJ50657.1 - 0.00011 21.0 0.7 0.21 10.1 0.0 3.7 3 1 1 4 4 4 1 Adaptin N terminal region HEAT_2 PF13646.6 CDJ50657.1 - 0.0016 18.8 20.1 0.2 12.1 0.1 7.5 6 2 3 10 10 10 3 HEAT repeats NUC173 PF08161.12 CDJ50657.1 - 0.012 15.3 0.0 3.8 7.1 0.0 4.0 3 1 0 4 4 4 0 NUC173 domain CLASP_N PF12348.8 CDJ50657.1 - 0.026 14.1 0.1 1.1 8.7 0.0 2.6 2 0 0 2 2 2 0 CLASP N terminal Arm PF00514.23 CDJ50657.1 - 0.083 13.0 3.3 73 3.6 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Bep_C_terminal PF17841.1 CDJ50657.1 - 0.14 12.4 3.0 0.45 10.8 3.0 1.8 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) PsbH PF00737.20 CDJ50657.1 - 6.1 6.7 6.7 4.2 7.2 0.4 2.9 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Myb_DNA-binding PF00249.31 CDJ50658.1 - 4.4e-08 33.2 1.3 0.0002 21.5 0.1 3.9 4 0 0 4 4 4 2 Myb-like DNA-binding domain NICE-1 PF15845.5 CDJ50658.1 - 0.024 15.4 0.6 0.024 15.4 0.6 3.9 3 0 0 3 3 3 0 Cysteine-rich C-terminal 1 family PRIMA1 PF16101.5 CDJ50658.1 - 0.95 9.5 3.8 3.6 7.6 3.8 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TFIIA PF03153.13 CDJ50660.1 - 0.17 11.8 55.1 0.19 11.7 55.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rieske_3 PF18465.1 CDJ50660.1 - 0.53 10.6 7.3 1.1 9.6 7.3 1.6 1 0 0 1 1 1 0 Rieske 3Fe-4S PepSY_TM PF03929.16 CDJ50660.1 - 2.7 7.6 5.0 2.8 7.5 5.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Utp14 PF04615.13 CDJ50660.1 - 6 5.3 39.7 7.5 5.0 39.7 1.0 1 0 0 1 1 1 0 Utp14 protein Nop14 PF04147.12 CDJ50660.1 - 9.1 4.3 32.8 11 4.1 32.8 1.0 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 CDJ50661.1 - 0.0013 18.2 0.0 0.6 9.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ50661.1 - 0.0055 16.0 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 CDJ50661.1 - 0.035 14.5 1.9 0.14 12.5 1.1 2.5 1 1 0 1 1 1 0 HEAT repeats Etmic-2 PF06670.11 CDJ50663.1 - 4.6e-62 210.1 7.3 1.4e-43 149.3 3.0 2.9 1 1 1 2 2 2 2 Microneme protein Etmic-2 TFIIA PF03153.13 CDJ50665.1 - 7.3e-05 22.9 26.6 7.3e-05 22.9 26.6 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ50665.1 - 0.00016 22.4 15.0 0.00016 22.4 15.0 3.3 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Mitofilin PF09731.9 CDJ50665.1 - 0.00021 20.3 11.2 0.00035 19.6 11.2 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein SR-25 PF10500.9 CDJ50665.1 - 0.0065 16.1 17.5 0.0065 16.1 17.5 2.6 3 0 0 3 3 2 1 Nuclear RNA-splicing-associated protein OATP PF03137.20 CDJ50665.1 - 0.024 12.9 0.9 0.039 12.2 0.9 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Plasmodium_Vir PF05795.11 CDJ50665.1 - 0.026 14.0 3.5 0.044 13.2 3.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Connexin PF00029.19 CDJ50665.1 - 0.028 14.2 1.6 0.049 13.4 1.6 1.4 1 0 0 1 1 1 0 Connexin Suf PF05843.14 CDJ50665.1 - 0.031 14.3 18.9 0.053 13.5 18.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.17 CDJ50665.1 - 0.031 14.4 5.4 0.066 13.4 5.4 1.6 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 CDJ50665.1 - 0.07 13.2 5.9 0.14 12.2 5.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 CDJ50665.1 - 0.083 11.2 18.7 0.12 10.6 18.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ50665.1 - 0.14 11.3 2.7 0.25 10.5 2.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter EMC3_TMCO1 PF01956.16 CDJ50665.1 - 0.2 11.4 4.4 0.34 10.6 4.4 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RR_TM4-6 PF06459.12 CDJ50665.1 - 0.2 11.5 12.6 0.48 10.2 12.6 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LMBR1 PF04791.16 CDJ50665.1 - 0.22 10.4 2.0 0.32 9.8 2.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CLN3 PF02487.17 CDJ50665.1 - 0.28 10.2 4.4 0.44 9.5 4.4 1.3 1 0 0 1 1 1 0 CLN3 protein eIF-3_zeta PF05091.12 CDJ50665.1 - 0.3 10.0 15.0 0.46 9.4 15.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) WDCP PF15390.6 CDJ50665.1 - 0.31 9.4 8.9 0.45 8.8 8.9 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family MAJIN PF15077.6 CDJ50665.1 - 0.34 10.7 7.7 0.65 9.7 7.7 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4179 PF13786.6 CDJ50665.1 - 0.35 11.4 6.5 0.98 9.9 0.0 4.2 3 2 0 3 3 3 0 Domain of unknown function (DUF4179) Band_3_cyto PF07565.13 CDJ50665.1 - 0.56 10.0 11.4 0.97 9.2 11.4 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BAF1_ABF1 PF04684.13 CDJ50665.1 - 0.56 9.2 17.0 0.024 13.7 8.7 2.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Pkinase_fungal PF17667.1 CDJ50665.1 - 0.67 8.7 4.0 0.98 8.1 4.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MecA PF05389.12 CDJ50665.1 - 0.73 9.4 6.4 1.8 8.2 6.4 1.6 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) RIFIN PF02009.16 CDJ50665.1 - 0.88 9.4 9.2 0.5 10.2 5.1 2.4 2 0 0 2 2 2 0 Rifin Serinc PF03348.15 CDJ50665.1 - 1.1 8.1 4.0 1.7 7.5 4.0 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) TERB2 PF15101.6 CDJ50665.1 - 2.7 8.0 13.5 5.6 7.0 13.5 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SprA-related PF12118.8 CDJ50665.1 - 3 6.9 36.5 2.3 7.3 26.7 2.8 3 0 0 3 3 3 0 SprA-related family Hamartin PF04388.12 CDJ50665.1 - 5.2 5.6 18.5 9.9 4.7 18.5 1.4 1 0 0 1 1 1 0 Hamartin protein Endostatin PF06482.11 CDJ50665.1 - 5.8 6.3 15.5 9.9 5.5 15.5 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Roughex PF06020.11 CDJ50665.1 - 5.9 5.9 15.5 11 5.0 15.5 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF5427 PF10310.9 CDJ50665.1 - 7.6 5.4 20.8 15 4.4 20.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) EIIBC-GUT_N PF03612.14 CDJ50665.1 - 7.7 6.2 10.0 17 5.1 10.0 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus EOS1 PF12326.8 CDJ50665.1 - 7.9 6.4 7.3 32 4.4 6.8 2.1 2 0 0 2 2 2 0 N-glycosylation protein Het-C PF07217.11 CDJ50665.1 - 8 4.9 11.1 12 4.3 11.1 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF4551 PF15087.6 CDJ50665.1 - 9.8 4.9 13.3 16 4.1 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TBPIP PF07106.13 CDJ50666.1 - 2e-16 59.7 0.0 4.1e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 CDJ50666.1 - 4.7e-05 23.4 0.1 0.00019 21.4 0.0 2.1 2 0 0 2 2 2 1 Leucine zipper with capping helix domain XRCC4 PF06632.12 CDJ50666.1 - 0.006 15.5 2.3 0.006 15.5 2.3 2.2 2 0 0 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 LUC7 PF03194.15 CDJ50666.1 - 0.012 15.2 9.3 0.012 15.2 9.3 1.5 2 0 0 2 2 2 0 LUC7 N_terminus SR-25 PF10500.9 CDJ50666.1 - 0.031 13.9 10.1 0.045 13.4 4.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MRPL52 PF18699.1 CDJ50666.1 - 0.044 14.0 2.8 0.044 14.0 2.8 2.6 4 0 0 4 4 4 0 Mitoribosomal protein mL52 RasGEF_N PF00618.20 CDJ50666.1 - 0.11 12.8 0.4 0.33 11.2 0.4 1.8 1 1 0 1 1 1 0 RasGEF N-terminal motif GHMP_kinases_N PF00288.26 CDJ50666.1 - 0.89 9.8 8.8 8 6.8 0.1 2.4 2 0 0 2 2 2 0 GHMP kinases N terminal domain Chorion_S16 PF05836.12 CDJ50666.1 - 4 7.7 10.1 1.4 9.2 1.3 2.4 2 0 0 2 2 2 0 Chorion protein S16 Cdh1_DBD_1 PF18196.1 CDJ50666.1 - 4 7.8 14.9 0.086 13.2 4.0 2.8 2 1 1 3 3 3 0 Chromodomain helicase DNA-binding domain 1 Glyco_hydro_9 PF00759.19 CDJ50666.1 - 5 6.4 12.2 0.47 9.8 1.2 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 DUF4865 PF16157.5 CDJ50666.1 - 7.9 6.4 7.4 0.66 9.9 2.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4865) GARP PF16731.5 CDJ50666.1 - 8 6.1 34.6 0.029 14.1 14.1 2.1 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma G0-G1_switch_2 PF15103.6 CDJ50667.1 - 0.003 17.9 0.2 0.0049 17.3 0.2 1.3 1 0 0 1 1 1 1 G0/G1 switch protein 2 WASH-7_C PF14746.6 CDJ50667.1 - 0.014 15.1 1.9 0.018 14.7 1.9 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal EOS1 PF12326.8 CDJ50667.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 N-glycosylation protein TBP PF00352.21 CDJ50668.1 - 2.6e-25 88.2 0.1 9.4e-23 80.0 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF515 PF04415.12 CDJ50668.1 - 6.8 5.0 7.7 9.8 4.4 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RVT_1 PF00078.27 CDJ50669.1 - 5.3e-07 29.4 0.0 9.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SLIDE PF09111.10 CDJ50670.1 - 3.2e-16 59.4 0.9 7.1e-16 58.3 0.1 2.0 2 0 0 2 2 2 1 SLIDE Myb_DNA-binding PF00249.31 CDJ50670.1 - 0.00069 19.8 0.6 1.7 8.9 0.0 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain HAND PF09110.11 CDJ50670.1 - 0.0024 18.6 2.2 0.0024 18.6 2.2 3.9 4 1 0 5 5 5 2 HAND Skp1 PF01466.19 CDJ50670.1 - 1.1 9.5 6.2 3.5 7.8 0.0 3.6 3 1 0 3 3 3 0 Skp1 family, dimerisation domain DUF4407 PF14362.6 CDJ50671.1 - 0.0044 16.4 30.1 0.0044 16.4 30.1 8.7 1 1 11 12 12 12 2 Domain of unknown function (DUF4407) Striatin PF08232.12 CDJ50671.1 - 0.014 16.0 11.3 0.014 16.0 11.3 11.3 2 2 6 9 9 9 0 Striatin family SR-25 PF10500.9 CDJ50672.1 - 3.8 7.0 30.5 0.84 9.2 7.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-HYPF PF07503.12 CDJ50672.1 - 9.2 6.1 9.1 2.6 7.9 0.7 2.2 2 0 0 2 2 2 0 HypF finger FAM176 PF14851.6 CDJ50673.1 - 0.023 14.3 5.2 0.025 14.2 5.2 1.1 1 0 0 1 1 1 0 FAM176 family DUF2722 PF10846.8 CDJ50673.1 - 0.031 13.2 19.9 0.034 13.1 19.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ50673.1 - 0.065 12.8 26.7 0.073 12.7 26.7 1.1 1 0 0 1 1 1 0 Spt20 family TERB2 PF15101.6 CDJ50673.1 - 0.065 13.3 14.1 0.073 13.1 14.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MMR1 PF08505.10 CDJ50673.1 - 0.088 13.1 12.5 0.095 13.0 12.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 CDJ50673.1 - 0.31 11.0 30.6 0.35 10.8 30.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4820 PF16091.5 CDJ50673.1 - 0.34 10.2 8.6 0.36 10.1 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) OATP PF03137.20 CDJ50673.1 - 0.41 8.9 2.9 0.41 8.9 2.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SpoIIP PF07454.11 CDJ50673.1 - 0.47 9.9 9.1 0.48 9.8 9.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Roughex PF06020.11 CDJ50673.1 - 0.66 9.0 13.9 0.71 8.9 13.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein FRQ PF09421.10 CDJ50673.1 - 0.79 7.7 13.6 0.82 7.6 13.6 1.0 1 0 0 1 1 1 0 Frequency clock protein EPL1 PF10513.9 CDJ50673.1 - 0.92 9.9 10.7 0.99 9.8 10.7 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Paf1 PF03985.13 CDJ50673.1 - 0.98 8.3 12.1 1.1 8.2 12.1 1.0 1 0 0 1 1 1 0 Paf1 DUF2681 PF10883.8 CDJ50673.1 - 1 9.8 16.2 1.8 9.0 16.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Sporozoite_P67 PF05642.11 CDJ50673.1 - 1 7.4 9.3 1.2 7.2 9.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Connexin PF00029.19 CDJ50673.1 - 1.1 9.0 5.8 1.1 8.9 5.8 1.1 1 0 0 1 1 1 0 Connexin BNR_3 PF13859.6 CDJ50673.1 - 1.5 8.0 8.7 1.6 7.9 8.7 1.1 1 0 0 1 1 1 0 BNR repeat-like domain Band_3_cyto PF07565.13 CDJ50673.1 - 1.8 8.3 11.0 2.1 8.1 11.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain UPF0560 PF10577.9 CDJ50673.1 - 1.9 6.9 14.6 1.9 6.9 14.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Membralin PF09746.9 CDJ50673.1 - 2.5 7.0 4.9 2.5 7.1 4.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein Lin-8 PF03353.15 CDJ50673.1 - 2.7 7.5 13.4 2.9 7.4 13.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NEMP PF10225.9 CDJ50673.1 - 3.1 7.4 5.2 3.4 7.3 5.2 1.1 1 0 0 1 1 1 0 NEMP family SLC12 PF03522.15 CDJ50673.1 - 3.4 6.6 12.1 3.6 6.5 12.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 V_ATPase_I PF01496.19 CDJ50673.1 - 4.5 5.0 9.2 4.6 5.0 9.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2052 PF09747.9 CDJ50673.1 - 4.7 7.3 13.9 4.8 7.3 13.9 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.17 CDJ50673.1 - 4.8 7.3 12.5 5.3 7.1 12.5 1.1 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.6 CDJ50673.1 - 5.6 7.1 13.5 6.8 6.8 13.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 CDJ50673.1 - 6.3 5.9 6.9 6.9 5.8 6.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CLN3 PF02487.17 CDJ50673.1 - 6.7 5.6 8.6 6.9 5.6 8.6 1.1 1 0 0 1 1 1 0 CLN3 protein Ctr PF04145.15 CDJ50673.1 - 7.1 7.2 6.3 8.3 7.0 6.3 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Neur_chan_memb PF02932.16 CDJ50673.1 - 9.2 6.2 11.7 9.1 6.3 11.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOG2 PF10428.9 CDJ50673.1 - 9.8 5.2 18.1 10 5.2 18.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Trp_oprn_chp PF09534.10 CDJ50674.1 - 0.11 12.2 5.5 0.15 11.9 5.3 1.3 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Rrn6 PF10214.9 CDJ50674.1 - 0.12 10.8 19.5 0.13 10.7 19.5 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FAM60A PF15396.6 CDJ50674.1 - 0.21 11.6 21.1 0.24 11.4 21.1 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Med19 PF10278.9 CDJ50674.1 - 0.23 11.3 19.4 0.31 10.9 19.4 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4603 PF15376.6 CDJ50674.1 - 0.42 7.9 24.1 0.48 7.8 24.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF1168 PF06658.12 CDJ50674.1 - 0.44 10.4 29.5 0.58 10.0 29.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) PAP1 PF08601.10 CDJ50674.1 - 1 9.0 18.8 1 9.0 18.8 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Vfa1 PF08432.10 CDJ50674.1 - 1.1 9.6 24.2 1.2 9.5 24.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SARAF PF06682.12 CDJ50674.1 - 1.1 8.8 13.7 1.4 8.5 13.7 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Peptidase_S49_N PF08496.10 CDJ50674.1 - 1.3 9.1 13.1 1.6 8.8 13.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Menin PF05053.13 CDJ50674.1 - 1.5 7.0 13.1 1.7 6.9 13.1 1.0 1 0 0 1 1 1 0 Menin MCM_bind PF09739.9 CDJ50674.1 - 2.1 6.7 14.4 2.2 6.6 14.4 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor GREB1 PF15782.5 CDJ50674.1 - 2.4 5.2 18.3 2.5 5.1 18.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NEMP PF10225.9 CDJ50674.1 - 2.5 7.7 6.4 2.6 7.7 6.4 1.0 1 0 0 1 1 1 0 NEMP family Nucleo_P87 PF07267.11 CDJ50674.1 - 3.1 6.6 9.9 3.1 6.6 9.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Apt1 PF10351.9 CDJ50674.1 - 3.2 6.5 24.0 3.2 6.5 24.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3807 PF12720.7 CDJ50674.1 - 3.4 7.9 21.2 3.9 7.7 21.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) NARP1 PF12569.8 CDJ50674.1 - 3.7 6.3 20.2 4.2 6.2 20.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.12 CDJ50674.1 - 4.1 6.7 24.8 4.9 6.4 24.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Neur_chan_memb PF02932.16 CDJ50674.1 - 5 7.1 9.1 4.8 7.2 9.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Miga PF10265.9 CDJ50674.1 - 5.8 5.8 15.9 6.1 5.7 15.9 1.0 1 0 0 1 1 1 0 Mitoguardin SAPS PF04499.15 CDJ50674.1 - 6.6 5.4 12.0 6.1 5.5 12.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.17 CDJ50674.1 - 6.7 6.8 14.1 7.7 6.6 14.1 1.2 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.13 CDJ50674.1 - 7.4 5.5 21.4 8.1 5.3 21.4 1.0 1 0 0 1 1 1 0 Paf1 EMC3_TMCO1 PF01956.16 CDJ50674.1 - 8.5 6.1 11.4 10 5.8 11.4 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MMR1 PF08505.10 CDJ50675.1 - 0.1 12.8 16.2 0.14 12.5 16.2 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein NPR3 PF03666.13 CDJ50675.1 - 0.12 11.2 12.2 0.14 10.9 12.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SID-1_RNA_chan PF13965.6 CDJ50675.1 - 0.38 9.1 5.7 0.46 8.8 5.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 CDJ50675.1 - 0.44 9.3 20.0 0.48 9.1 20.0 1.2 1 0 0 1 1 1 0 Presenilin MAT1 PF06391.13 CDJ50675.1 - 0.55 10.0 18.1 0.72 9.6 18.1 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Sec62 PF03839.16 CDJ50675.1 - 0.62 9.5 11.7 0.77 9.2 11.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 FAM60A PF15396.6 CDJ50675.1 - 0.94 9.4 15.7 1.4 8.9 15.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A ALMT PF11744.8 CDJ50675.1 - 1 8.1 14.1 1.2 7.9 14.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Miga PF10265.9 CDJ50675.1 - 2.1 7.2 14.4 2.3 7.1 14.4 1.1 1 0 0 1 1 1 0 Mitoguardin Lin-8 PF03353.15 CDJ50675.1 - 2.4 7.6 16.2 2.8 7.4 16.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Med15 PF09606.10 CDJ50675.1 - 2.8 6.5 41.5 4.1 6.0 41.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SAGA-Tad1 PF12767.7 CDJ50675.1 - 2.9 7.6 14.6 3.1 7.5 14.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Draxin PF15550.6 CDJ50675.1 - 3.1 7.6 13.0 3.6 7.4 13.0 1.2 1 0 0 1 1 1 0 Draxin SLC12 PF03522.15 CDJ50675.1 - 3.2 6.7 17.2 4 6.4 17.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDK5_activator PF03261.15 CDJ50675.1 - 3.8 7.0 16.0 4.4 6.7 16.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4551 PF15087.6 CDJ50675.1 - 3.8 6.2 15.0 4.2 6.1 15.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hamartin PF04388.12 CDJ50675.1 - 4 6.0 15.9 4.4 5.8 15.9 1.2 1 0 0 1 1 1 0 Hamartin protein DUF572 PF04502.13 CDJ50675.1 - 5.4 6.5 16.4 6.3 6.3 16.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ndc1_Nup PF09531.10 CDJ50675.1 - 5.6 5.5 23.0 6.4 5.3 23.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 CDJ50675.1 - 5.6 6.9 12.5 7 6.6 12.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOBP PF15279.6 CDJ50675.1 - 5.9 7.4 20.4 7.8 7.0 20.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Sin_N PF04801.13 CDJ50675.1 - 6.2 5.9 24.3 7.2 5.7 24.3 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Zip PF02535.22 CDJ50675.1 - 6.3 5.9 8.6 7.2 5.7 8.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Membralin PF09746.9 CDJ50675.1 - 7 5.6 7.4 7.7 5.4 7.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein Hid1 PF12722.7 CDJ50675.1 - 7.1 4.6 17.9 7.6 4.5 17.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 CDJ50675.1 - 8.1 6.2 19.5 11 5.7 19.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 CDJ50676.1 - 0.00035 20.7 60.8 0.00035 20.7 60.8 13.7 3 3 5 8 8 8 1 Transcription factor IIA, alpha/beta subunit RCC1 PF00415.18 CDJ50680.1 - 1.4e-22 80.1 20.3 1.9e-06 28.4 1.3 9.3 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ50680.1 - 3.6e-20 71.2 32.6 3.9e-07 29.7 3.0 6.7 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Sec7 PF01369.20 CDJ50681.1 - 1.6e-37 129.0 0.0 1.6e-37 129.0 0.0 1.5 2 0 0 2 2 2 1 Sec7 domain Use1 PF09753.9 CDJ50681.1 - 8 6.1 18.3 25 4.5 18.3 1.8 1 0 0 1 1 1 0 Membrane fusion protein Use1 Sulfate_transp PF00916.20 CDJ50682.1 - 1.6e-80 270.7 15.2 2.2e-80 270.3 15.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDJ50682.1 - 5.4e-18 64.7 0.0 8.6e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CDJ50682.1 - 0.0058 16.9 0.1 0.026 14.9 0.0 2.3 2 0 0 2 2 2 1 STAS domain UL41A PF17591.2 CDJ50682.1 - 0.097 12.8 3.7 1 9.5 0.0 3.0 3 0 0 3 3 3 0 Herpesvirus UL41A zf-MIZ PF02891.20 CDJ50683.1 - 3.8e-16 58.5 4.0 3.8e-16 58.5 4.0 2.8 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger SAP PF02037.27 CDJ50683.1 - 4.7e-06 26.2 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 SAP domain PHD_2 PF13831.6 CDJ50683.1 - 0.00059 19.3 9.1 0.00059 19.3 9.1 2.6 2 1 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 CDJ50683.1 - 0.25 11.3 4.1 1.1 9.3 4.1 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-Nse PF11789.8 CDJ50683.1 - 0.49 10.2 7.3 0.28 11.0 1.0 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 CDJ50683.1 - 0.55 10.2 19.5 1.7 8.6 10.2 2.9 2 0 0 2 2 2 0 PHD-finger RAP1 PF07218.11 CDJ50686.1 - 0.013 13.9 6.9 0.016 13.6 6.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4551 PF15087.6 CDJ50688.1 - 0.079 11.8 13.2 0.078 11.8 13.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SR-25 PF10500.9 CDJ50688.1 - 0.14 11.8 13.5 0.19 11.3 13.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ50688.1 - 0.22 11.5 21.6 0.26 11.2 21.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4820 PF16091.5 CDJ50688.1 - 0.71 9.2 15.0 0.9 8.9 15.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM60A PF15396.6 CDJ50688.1 - 3 7.8 9.0 3.8 7.4 9.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A N6_N4_Mtase PF01555.18 CDJ50689.1 - 3.3e-05 23.7 0.0 3.1 7.5 0.0 5.5 4 2 1 5 5 5 2 DNA methylase Herpes_capsid PF06112.11 CDJ50689.1 - 0.00039 20.5 12.8 0.00039 20.5 12.8 16.8 11 5 6 17 17 17 1 Gammaherpesvirus capsid protein Spt20 PF12090.8 CDJ50691.1 - 0.00095 18.8 19.4 0.00095 18.8 19.4 4.1 2 1 1 3 3 3 1 Spt20 family Pex14_N PF04695.13 CDJ50691.1 - 0.0053 17.4 1.8 0.0053 17.4 1.8 4.3 3 1 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.9 CDJ50692.1 - 4 7.7 89.9 6.6 7.0 22.4 3.2 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Med15 PF09606.10 CDJ50692.1 - 6.7 5.3 43.3 9.7 4.7 43.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.15 CDJ50693.1 - 0.78 8.6 8.7 0.85 8.5 8.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM176 PF14851.6 CDJ50693.1 - 1 9.0 15.7 0.13 11.9 11.2 1.7 1 1 1 2 2 2 0 FAM176 family Mem_trans PF03547.18 CDJ50693.1 - 1.2 7.4 6.6 1.2 7.4 6.6 1.1 1 0 0 1 1 1 0 Membrane transport protein Orf78 PF06024.12 CDJ50693.1 - 1.3 9.3 11.2 0.23 11.8 5.5 2.0 1 1 1 2 2 2 0 Orf78 (ac78) CSG2 PF16965.5 CDJ50693.1 - 1.3 7.9 7.4 1.4 7.8 7.4 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator V_ATPase_I PF01496.19 CDJ50693.1 - 2.8 5.7 20.9 3.1 5.6 20.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ50693.1 - 3.8 6.2 21.7 4.3 6.0 21.7 1.1 1 0 0 1 1 1 0 Presenilin OSTbeta PF15048.6 CDJ50693.1 - 5.3 7.2 10.2 0.96 9.6 5.8 1.8 1 1 1 2 2 2 0 Organic solute transporter subunit beta protein SID-1_RNA_chan PF13965.6 CDJ50693.1 - 5.7 5.2 6.4 5.9 5.2 6.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDHD PF02862.17 CDJ50693.1 - 7.1 6.7 15.7 9 6.4 15.7 1.2 1 0 0 1 1 1 0 DDHD domain RPN2_C PF18004.1 CDJ50695.1 - 0.052 13.5 17.9 0.057 13.3 17.9 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CobT PF06213.12 CDJ50695.1 - 0.77 9.1 24.7 0.76 9.1 24.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3408 PF11888.8 CDJ50695.1 - 1.6 8.9 20.1 1.7 8.8 20.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Pannexin_like PF12534.8 CDJ50695.1 - 1.8 7.6 14.8 2 7.4 14.8 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 SpoIIP PF07454.11 CDJ50695.1 - 2 7.8 21.5 2 7.8 21.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AIF_C PF14721.6 CDJ50695.1 - 2.1 8.7 15.1 2.2 8.6 15.1 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CPSF100_C PF13299.6 CDJ50695.1 - 2.3 8.4 17.1 2.2 8.4 17.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PRC2_HTH_1 PF18118.1 CDJ50695.1 - 2.7 8.9 14.5 2.9 8.8 14.5 1.2 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Tim54 PF11711.8 CDJ50695.1 - 2.9 6.6 17.8 2.9 6.6 17.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 CDJ50695.1 - 3.5 7.3 17.5 3.4 7.3 17.5 1.1 1 0 0 1 1 1 0 Connexin CCDC53 PF10152.9 CDJ50695.1 - 3.9 7.9 20.4 3.9 7.9 20.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TFB6 PF17110.5 CDJ50695.1 - 3.9 7.2 11.6 4 7.1 11.6 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH YABBY PF04690.13 CDJ50695.1 - 4.2 7.9 16.0 4.4 7.9 16.0 1.1 1 0 0 1 1 1 0 YABBY protein Membralin PF09746.9 CDJ50695.1 - 4.7 6.1 15.2 5 6.1 15.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein EIIBC-GUT_N PF03612.14 CDJ50695.1 - 5.1 6.8 17.9 5.9 6.6 17.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2828 PF11443.8 CDJ50695.1 - 5.6 4.9 20.8 5.5 4.9 20.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF702 PF05142.12 CDJ50695.1 - 5.6 7.4 21.3 6.3 7.3 21.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) PPL5 PF18168.1 CDJ50695.1 - 5.7 6.1 15.7 5.9 6.1 15.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF1178 PF06676.11 CDJ50695.1 - 6.1 7.2 22.3 7.2 7.0 22.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) TCP PF03634.13 CDJ50695.1 - 7 7.2 23.6 8.1 7.0 23.6 1.1 1 0 0 1 1 1 0 TCP family transcription factor Baculo_PP31 PF05311.11 CDJ50695.1 - 7.1 6.0 20.0 7.1 6.0 20.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF3464 PF11947.8 CDJ50695.1 - 7.4 6.3 19.6 8.6 6.1 19.6 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FAM176 PF14851.6 CDJ50695.1 - 7.6 6.2 13.8 9 6.0 13.8 1.2 1 0 0 1 1 1 0 FAM176 family Paf1 PF03985.13 CDJ50695.1 - 7.6 5.4 23.2 7.3 5.5 23.2 1.0 1 0 0 1 1 1 0 Paf1 DUF4746 PF15928.5 CDJ50695.1 - 7.9 5.8 15.2 7.5 5.9 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Dynamin_N PF00350.23 CDJ50695.1 - 8.8 6.4 13.4 9.8 6.2 13.4 1.1 1 0 0 1 1 1 0 Dynamin family Peptidase_S49_N PF08496.10 CDJ50695.1 - 9 6.3 21.9 10 6.2 21.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal G0-G1_switch_2 PF15103.6 CDJ50695.1 - 9.4 6.7 15.9 12 6.4 15.9 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 RR_TM4-6 PF06459.12 CDJ50695.1 - 9.8 5.9 22.9 10 5.8 22.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 CDJ50695.1 - 9.8 5.0 22.2 11 4.8 22.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CLP1_P PF16575.5 CDJ50696.1 - 7.6e-15 55.2 0.4 4.1e-11 43.0 0.0 2.7 2 1 1 3 3 3 2 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CDJ50696.1 - 7.9e-13 48.4 0.0 1.6e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_16 PF13191.6 CDJ50696.1 - 0.0031 17.9 6.4 0.053 13.9 3.4 3.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CDJ50696.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 CDJ50696.1 - 0.042 13.6 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 CDJ50696.1 - 0.047 14.2 0.5 0.11 13.1 0.1 1.7 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 CDJ50696.1 - 0.065 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 CDJ50696.1 - 0.11 12.9 0.7 2.7 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 CDJ50696.1 - 0.13 12.3 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CDJ50696.1 - 0.19 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 CDJ50696.1 - 0.46 10.1 4.2 1 9.0 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA PF00004.29 CDJ50697.1 - 4.9e-41 140.3 0.0 9.9e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ50697.1 - 8.4e-10 38.3 0.1 2e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CDJ50697.1 - 8.9e-06 26.0 0.2 0.0066 16.7 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 CDJ50697.1 - 1.4e-05 25.1 0.1 0.00011 22.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ50697.1 - 0.00019 21.9 0.2 0.0028 18.0 0.1 2.2 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CDJ50697.1 - 0.00032 20.5 0.0 0.0014 18.4 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDJ50697.1 - 0.00066 19.8 0.1 0.0023 18.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 CDJ50697.1 - 0.0042 16.8 0.3 0.064 13.0 0.1 2.8 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CDJ50697.1 - 0.0074 16.8 0.0 0.02 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CDJ50697.1 - 0.0088 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CDJ50697.1 - 0.01 15.3 0.0 0.031 13.8 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CDJ50697.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CDJ50697.1 - 0.031 13.5 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 CDJ50697.1 - 0.041 13.7 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CDJ50697.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 CDJ50697.1 - 0.053 12.6 0.0 0.099 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TIP49 PF06068.13 CDJ50697.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 CDJ50697.1 - 0.1 13.0 0.0 0.3 11.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.26 CDJ50697.1 - 0.11 12.2 0.0 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CDJ50697.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RskA PF10099.9 CDJ50698.1 - 0.026 14.8 15.6 0.24 11.7 0.1 3.1 2 1 1 3 3 3 0 Anti-sigma-K factor rskA GramPos_pilinD3 PF16570.5 CDJ50698.1 - 0.056 14.2 0.6 0.087 13.6 0.6 1.3 1 0 0 1 1 1 0 Gram-positive pilin backbone subunit 3, Cna-B-like domain DUF4148 PF13663.6 CDJ50698.1 - 0.18 12.0 9.4 2 8.7 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) RskA PF10099.9 CDJ50699.1 - 0.00023 21.5 6.7 0.00036 20.9 6.7 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ50699.1 - 0.011 14.5 8.0 0.014 14.1 8.0 1.1 1 0 0 1 1 1 0 Presenilin Chorion_2 PF03964.15 CDJ50699.1 - 0.014 16.2 6.6 0.014 16.2 6.6 2.1 2 0 0 2 2 2 0 Chorion family 2 TFIIA PF03153.13 CDJ50699.1 - 0.12 12.3 24.1 0.17 11.9 24.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EOS1 PF12326.8 CDJ50699.1 - 0.18 11.7 1.6 0.26 11.2 1.6 1.3 1 1 0 1 1 1 0 N-glycosylation protein CPSF100_C PF13299.6 CDJ50699.1 - 2.6 8.2 7.3 0.63 10.2 3.8 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4834 PF16118.5 CDJ50699.1 - 2.9 8.9 15.0 0.43 11.6 6.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ50699.1 - 6.5 6.4 6.0 1.5 8.5 3.0 1.5 2 0 0 2 2 2 0 Connexin BT1 PF03092.16 CDJ50701.1 - 2e-77 260.6 20.8 3.6e-54 183.9 13.9 2.0 1 1 1 2 2 2 2 BT1 family DC_STAMP PF07782.13 CDJ50701.1 - 0.081 12.7 2.7 0.12 12.2 1.1 2.0 2 0 0 2 2 2 0 DC-STAMP-like protein V_ATPase_I PF01496.19 CDJ50701.1 - 2.1 6.1 3.6 3.3 5.5 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-CCHC PF00098.23 CDJ50702.1 - 2.4e-05 24.2 14.8 0.00047 20.1 3.5 3.3 2 1 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 CDJ50702.1 - 0.019 14.7 1.3 0.019 14.7 1.3 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ50702.1 - 0.6 9.9 12.7 0.057 13.1 2.9 2.5 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 CDJ50702.1 - 1.7 8.7 7.5 0.25 11.3 2.2 2.3 2 0 0 2 2 2 0 Zinc knuckle RVP_2 PF08284.11 CDJ50703.1 - 4.9e-07 29.6 0.0 8.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ50703.1 - 2.9e-05 24.6 0.0 7.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ50703.1 - 0.00048 20.6 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDJ50703.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 CDJ50704.1 - 1.5e-15 57.3 0.0 2.7e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ50705.1 - 7.2e-15 55.2 0.1 1.6e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ50705.1 - 8.6e-15 54.6 1.0 2.7e-14 53.0 1.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ50705.1 - 4e-05 23.7 0.8 9.9e-05 22.5 0.8 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 CDJ50705.1 - 0.00017 21.9 0.0 0.00038 20.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ50705.1 - 0.00041 20.3 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SR-25 PF10500.9 CDJ50708.1 - 2.1e-05 24.3 8.9 2.7e-05 23.9 8.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IATP PF04568.12 CDJ50708.1 - 0.0016 18.9 3.5 0.0022 18.4 3.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP THRAP3_BCLAF1 PF15440.6 CDJ50708.1 - 0.016 14.2 4.7 0.017 14.1 4.7 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family AF-4 PF05110.13 CDJ50708.1 - 0.032 12.4 18.6 0.038 12.1 18.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NAM-associated PF14303.6 CDJ50708.1 - 0.066 13.9 2.6 0.086 13.6 2.6 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Serine_rich PF08824.10 CDJ50708.1 - 0.079 13.0 2.9 0.11 12.5 2.9 1.1 1 0 0 1 1 1 0 Serine rich protein interaction domain FAM199X PF15814.5 CDJ50708.1 - 0.42 9.6 10.6 0.55 9.2 10.6 1.1 1 0 0 1 1 1 0 Protein family FAM199X CCSAP PF15748.5 CDJ50708.1 - 0.78 9.9 7.1 0.97 9.6 7.1 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF3573 PF12097.8 CDJ50708.1 - 2.2 7.0 5.5 2.8 6.7 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) CDK2AP PF09806.9 CDJ50708.1 - 2.4 8.2 8.7 3.3 7.7 8.7 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3446 PF11928.8 CDJ50708.1 - 3.5 8.0 17.3 5 7.5 15.3 1.9 2 0 0 2 2 2 0 Early growth response N-terminal domain Spt20 PF12090.8 CDJ50708.1 - 7 6.2 14.2 8.5 5.9 14.2 1.1 1 0 0 1 1 1 0 Spt20 family Corona_nucleoca PF00937.18 CDJ50708.1 - 8.8 5.3 11.3 11 5.0 11.3 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FAM199X PF15814.5 CDJ50709.1 - 0.63 9.0 7.1 0.83 8.6 7.1 1.1 1 0 0 1 1 1 0 Protein family FAM199X PPV_E1_N PF00524.18 CDJ50709.1 - 2.4 8.6 7.3 3.4 8.1 7.2 1.4 1 1 0 1 1 1 0 E1 Protein, N terminal domain TFIIA PF03153.13 CDJ50709.1 - 3 7.8 20.5 3.3 7.6 20.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L28 PF00830.19 CDJ50711.1 - 9.7e-07 28.9 1.1 2.2e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal L28 family V-SNARE_C PF12352.8 CDJ50712.1 - 3.8e-07 30.3 2.9 1e-06 28.9 2.9 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 CDJ50712.1 - 0.045 11.7 13.2 0.088 10.7 13.2 1.5 1 1 0 1 1 1 0 Prominin DUF1846 PF08903.11 CDJ50712.1 - 0.15 10.6 3.0 0.099 11.2 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1846) Mitovir_RNA_pol PF05919.11 CDJ50712.1 - 0.17 11.0 4.1 0.2 10.8 4.1 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase AsnA PF03590.15 CDJ50712.1 - 0.49 10.1 3.6 0.31 10.7 0.9 1.8 2 1 0 2 2 2 0 Aspartate-ammonia ligase ALMT PF11744.8 CDJ50712.1 - 8.2 5.1 10.4 10 4.8 10.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Amidohydro_1 PF01979.20 CDJ50713.1 - 2.8e-05 23.6 0.1 0.0003 20.2 0.1 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 CDJ50713.1 - 6.3e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Asp PF00026.23 CDJ50714.1 - 3.7e-27 95.6 0.0 2.5e-13 50.1 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ50714.1 - 6.7e-09 36.2 0.0 2.7e-07 31.0 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Peptidase_M16 PF00675.20 CDJ50715.1 - 3.3e-43 147.2 0.9 1.2e-42 145.4 0.0 2.4 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 CDJ50715.1 - 7.6e-32 110.7 0.0 2e-30 106.1 0.0 2.2 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CDJ50715.1 - 2.6e-11 43.8 0.7 1.9e-07 31.2 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain STI1 PF17830.1 CDJ50715.1 - 0.035 14.0 0.1 13 5.8 0.1 3.1 2 1 0 2 2 2 0 STI1 domain Helicase_C PF00271.31 CDJ50716.1 - 5.7e-10 39.5 0.0 2e-08 34.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ50716.1 - 8.6e-10 38.7 0.0 1.1e-05 25.3 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase ABC_tran PF00005.27 CDJ50717.1 - 5.8e-23 81.9 0.0 8.7e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CDJ50717.1 - 1.1e-20 74.0 22.7 1.1e-20 74.0 22.7 1.4 2 0 0 2 2 2 1 ABC-2 type transporter AAA_25 PF13481.6 CDJ50717.1 - 7.1e-06 25.7 0.6 0.037 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 CDJ50717.1 - 0.0027 16.9 17.8 0.0027 16.9 17.8 1.5 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 CDJ50717.1 - 0.0081 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 CDJ50717.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 CDJ50717.1 - 0.016 15.8 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CDJ50717.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 CDJ50717.1 - 0.039 13.7 0.0 0.19 11.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CDJ50717.1 - 0.055 13.7 0.1 0.21 11.9 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDJ50717.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ50717.1 - 0.18 11.6 0.3 0.42 10.4 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CDJ50717.1 - 0.18 12.2 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 CDJ50717.1 - 0.21 12.0 0.0 0.34 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 CDJ50718.1 - 3.4e-08 34.2 0.0 5.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FliS PF02561.14 CDJ50719.1 - 0.29 11.4 2.2 1.5 9.1 0.3 2.6 2 0 0 2 2 2 0 Flagellar protein FliS DUF4085 PF13315.6 CDJ50719.1 - 5.9 6.5 7.4 7.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Pantoate_transf PF02548.15 CDJ50720.1 - 1.4e-68 231.1 9.3 2.9e-41 141.6 0.2 3.2 3 1 1 4 4 4 2 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.11 CDJ50720.1 - 1.8e-24 86.3 0.4 3.1e-24 85.6 0.4 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CDJ50720.1 - 0.0023 17.6 0.0 0.23 11.1 0.0 2.6 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA TFX_C PF14601.6 CDJ50720.1 - 0.12 12.3 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term G6PD_C PF02781.16 CDJ50721.1 - 2.5e-65 220.5 0.0 7.9e-34 117.2 0.0 2.6 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CDJ50721.1 - 2.8e-50 171.4 0.0 8.2e-50 169.9 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glucosamine_iso PF01182.20 CDJ50721.1 - 8.7e-37 127.2 0.0 1.5e-36 126.4 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NAD_synthase PF02540.17 CDJ50721.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase RT_RNaseH_2 PF17919.1 CDJ50722.1 - 2.4e-17 62.8 0.0 3.6e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ50722.1 - 2.7e-16 59.7 0.0 4.3e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rep_fac-A_C PF08646.10 CDJ50723.1 - 1.7e-27 96.0 0.3 3.4e-27 95.0 0.3 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CDJ50723.1 - 1.5e-14 53.7 0.0 2.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Replication protein A OB domain CDC24_OB3 PF17244.2 CDJ50723.1 - 0.055 13.2 0.6 0.5 10.1 0.3 2.1 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 PLATZ PF04640.14 CDJ50723.1 - 0.057 14.0 0.7 0.12 13.0 0.7 1.5 1 0 0 1 1 1 0 PLATZ transcription factor JAMP PF05571.12 CDJ50723.1 - 0.34 10.5 2.3 0.6 9.7 2.3 1.3 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein SUIM_assoc PF16619.5 CDJ50723.1 - 2.4 8.3 6.8 5.5 7.1 3.7 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ50724.1 - 0.00065 18.8 0.6 0.00065 18.8 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ50724.1 - 0.0083 16.1 2.2 0.01 15.9 2.2 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ50724.1 - 0.0091 15.6 8.8 0.0091 15.6 8.8 1.1 1 0 0 1 1 1 1 Spt20 family Rax2 PF12768.7 CDJ50724.1 - 0.048 13.1 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TFIIA PF03153.13 CDJ50724.1 - 0.16 11.9 8.9 0.17 11.9 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2229 PF09989.9 CDJ50724.1 - 0.25 11.0 0.7 0.29 10.7 0.7 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Activator_LAG-3 PF11498.8 CDJ50724.1 - 0.95 8.4 17.7 1.1 8.2 17.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ubiquitin PF00240.23 CDJ50725.1 - 3.9e-10 39.3 2.9 3.8e-07 29.8 0.0 4.1 4 0 0 4 4 4 2 Ubiquitin family Rad60-SLD_2 PF13881.6 CDJ50725.1 - 4.8e-07 29.9 0.0 4.8e-07 29.9 0.0 6.7 5 2 2 7 7 7 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 CDJ50725.1 - 0.00065 20.3 0.7 0.004 17.8 0.7 2.4 1 1 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DUF2722 PF10846.8 CDJ50725.1 - 0.0012 17.9 10.5 0.0012 17.9 10.5 7.9 4 1 1 6 6 6 4 Protein of unknown function (DUF2722) AAA_11 PF13086.6 CDJ50725.1 - 0.0042 16.9 11.3 0.0042 16.9 11.3 4.6 2 1 0 2 2 2 1 AAA domain DUF4484 PF14831.6 CDJ50725.1 - 0.0082 16.2 2.6 0.0082 16.2 2.6 6.4 3 1 1 4 4 4 1 Domain of unknown function (DUF4484) RAP1 PF07218.11 CDJ50725.1 - 0.22 9.8 11.1 0.32 9.2 11.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-HIT PF04438.16 CDJ50726.1 - 1.4e-06 28.0 9.9 2.4e-06 27.3 9.9 1.3 1 0 0 1 1 1 1 HIT zinc finger CutA1 PF03091.15 CDJ50726.1 - 0.00089 19.1 0.7 0.0027 17.5 0.7 1.8 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein SPX PF03105.19 CDJ50726.1 - 0.35 10.7 33.0 0.77 9.6 13.5 2.2 2 0 0 2 2 2 0 SPX domain zf-MYND PF01753.18 CDJ50726.1 - 0.58 10.3 9.6 1.5 9.0 9.6 1.6 1 0 0 1 1 1 0 MYND finger Sporozoite_P67 PF05642.11 CDJ50728.1 - 1 7.4 19.1 0.05 11.7 7.3 2.0 1 1 0 2 2 2 0 Sporozoite P67 surface antigen Lin-8 PF03353.15 CDJ50730.1 - 0.5 9.9 11.9 0.52 9.8 11.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Rrn6 PF10214.9 CDJ50730.1 - 1.3 7.4 19.2 1.4 7.3 19.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Grg1 PF11034.8 CDJ50730.1 - 1.3 9.3 7.8 37 4.6 7.8 2.5 1 1 0 1 1 1 0 Glucose-repressible protein Grg1 Macoilin PF09726.9 CDJ50730.1 - 3.3 6.1 19.7 4.1 5.8 19.7 1.0 1 0 0 1 1 1 0 Macoilin family Cwf_Cwc_15 PF04889.12 CDJ50730.1 - 3.6 7.2 17.0 4.5 6.9 17.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PI3K_1B_p101 PF10486.9 CDJ50730.1 - 6.5 4.4 13.4 6.9 4.3 13.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Miga PF10265.9 CDJ50730.1 - 8.4 5.2 12.0 8.8 5.2 12.0 1.0 1 0 0 1 1 1 0 Mitoguardin DUF382 PF04037.13 CDJ50731.1 - 2.5e-10 40.6 0.9 2.5e-10 40.6 0.9 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF382) RskA PF10099.9 CDJ50731.1 - 0.0028 18.0 19.5 0.0028 18.0 19.5 3.9 3 1 0 3 3 3 1 Anti-sigma-K factor rskA A1_Propeptide PF07966.12 CDJ50731.1 - 4.3 7.3 6.1 1.4 8.9 3.2 1.7 2 0 0 2 2 2 0 A1 Propeptide SRP-alpha_N PF04086.13 CDJ50731.1 - 4.4 7.1 55.7 1.7 8.5 12.7 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Bud13 PF09736.9 CDJ50732.1 - 0.4 11.1 13.0 0.49 10.8 13.0 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Hydin_ADK PF17213.3 CDJ50732.1 - 2.6 8.3 23.0 3.2 8.0 23.0 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF966 PF06136.13 CDJ50732.1 - 3.3 7.3 24.6 3.9 7.1 24.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SOG2 PF10428.9 CDJ50732.1 - 7.6 5.6 32.1 9.3 5.3 32.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CDJ50732.1 - 8 5.1 23.7 11 4.7 23.7 1.2 1 0 0 1 1 1 0 Presenilin Oxysterol_BP PF01237.18 CDJ50734.1 - 5e-91 305.3 7.1 1.5e-59 201.7 3.7 8.4 8 3 1 9 9 9 2 Oxysterol-binding protein PH PF00169.29 CDJ50734.1 - 1e-11 45.3 0.3 3.3e-11 43.6 0.3 2.0 1 0 0 1 1 1 1 PH domain NST1 PF13945.6 CDJ50735.1 - 0.097 12.8 24.6 0.32 11.1 15.1 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator MRP-S31 PF15433.6 CDJ50735.1 - 0.87 9.2 17.9 1.6 8.3 4.5 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 TFIIA PF03153.13 CDJ50735.1 - 2.8 7.9 46.3 4.6 7.1 46.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SKI PF01202.22 CDJ50735.1 - 6 7.0 10.7 12 5.9 1.5 2.1 2 0 0 2 2 2 0 Shikimate kinase Sacchrp_dh_C PF16653.5 CDJ50735.1 - 7.2 6.6 7.0 2 8.4 1.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase C-terminal domain Shadoo PF14999.6 CDJ50736.1 - 0.0026 17.8 8.7 0.0038 17.3 8.7 1.2 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective DUF2403 PF10290.9 CDJ50736.1 - 0.044 14.2 0.5 0.069 13.6 0.5 1.5 1 1 0 1 1 1 0 Glycine-rich protein domain (DUF2403) SR-25 PF10500.9 CDJ50736.1 - 0.091 12.4 16.5 0.12 12.0 16.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Baculo_LEF5_C PF11792.8 CDJ50736.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain DUF1635 PF07795.11 CDJ50736.1 - 0.31 10.8 5.2 0.42 10.4 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF3824 PF12868.7 CDJ50736.1 - 0.7 10.6 4.7 1.1 9.9 4.7 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Apt1 PF10351.9 CDJ50736.1 - 1.1 8.0 4.2 1.2 7.9 4.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4692 PF15763.5 CDJ50736.1 - 1.6 9.2 6.6 2.1 8.8 6.6 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Macoilin PF09726.9 CDJ50736.1 - 2.7 6.4 8.1 3.2 6.2 8.1 1.1 1 0 0 1 1 1 0 Macoilin family PPIP5K2_N PF18086.1 CDJ50737.1 - 3.8e-10 39.8 0.0 6.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Dehydrin PF00257.19 CDJ50737.1 - 0.019 15.5 20.5 0.54 10.8 0.0 3.4 3 0 0 3 3 3 0 Dehydrin His_Phos_2 PF00328.22 CDJ50738.1 - 4.6e-29 102.0 0.9 1.4e-26 93.7 0.1 5.9 5 1 0 5 5 5 3 Histidine phosphatase superfamily (branch 2) RskA PF10099.9 CDJ50738.1 - 0.009 16.3 9.9 0.009 16.3 9.9 13.4 6 3 5 11 11 11 3 Anti-sigma-K factor rskA SARAF PF06682.12 CDJ50740.1 - 0.075 12.7 27.2 0.096 12.3 27.2 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Clr2 PF10383.9 CDJ50740.1 - 0.23 12.2 12.7 2.1 9.1 7.3 2.2 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 DUF572 PF04502.13 CDJ50740.1 - 0.47 10.0 26.5 0.66 9.5 26.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF5523 PF17661.1 CDJ50740.1 - 1.2 8.7 22.0 1.8 8.2 22.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Nha1_C PF08619.10 CDJ50740.1 - 4.8 6.3 36.5 0.63 9.2 4.7 2.0 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus GREB1 PF15782.5 CDJ50740.1 - 7 3.6 29.7 8.2 3.4 29.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 CDJ50741.1 - 0.0067 15.6 6.8 0.008 15.3 6.8 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) SOBP PF15279.6 CDJ50741.1 - 0.13 12.8 16.2 0.17 12.5 16.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein eIF-3_zeta PF05091.12 CDJ50741.1 - 0.23 10.4 8.8 0.27 10.2 8.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ50741.1 - 0.38 9.0 26.1 0.45 8.7 26.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CLN3 PF02487.17 CDJ50741.1 - 0.4 9.7 2.0 0.68 8.9 2.0 1.3 1 0 0 1 1 1 0 CLN3 protein Hamartin PF04388.12 CDJ50741.1 - 1.8 7.1 10.9 2.2 6.9 10.9 1.1 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 CDJ50741.1 - 6.7 5.3 15.9 8.6 4.9 15.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4813 PF16072.5 CDJ50741.1 - 6.9 6.2 37.3 9.2 5.8 37.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF5585 PF17823.1 CDJ50741.1 - 7.9 5.3 28.8 10 5.0 28.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Hid1 PF12722.7 CDJ50741.1 - 8.6 4.3 11.7 9.8 4.2 11.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SARAF PF06682.12 CDJ50741.1 - 9.9 5.7 18.8 9.8 5.7 17.9 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CBP_BcsG PF11658.8 CDJ50742.1 - 0.00043 18.8 14.4 0.00046 18.7 14.4 1.0 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG SID-1_RNA_chan PF13965.6 CDJ50742.1 - 0.02 13.4 9.7 0.02 13.3 9.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.10 CDJ50742.1 - 0.022 14.8 18.2 0.023 14.7 18.2 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ureide_permease PF07168.11 CDJ50742.1 - 0.026 13.3 7.9 0.031 13.0 7.9 1.1 1 0 0 1 1 1 0 Ureide permease V_ATPase_I PF01496.19 CDJ50742.1 - 0.034 12.1 17.9 0.033 12.1 17.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAP2_3 PF14378.6 CDJ50742.1 - 0.039 13.6 0.2 0.049 13.3 0.2 1.3 1 1 0 1 1 1 0 PAP2 superfamily Serinc PF03348.15 CDJ50742.1 - 0.05 12.5 12.2 0.053 12.4 12.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CLN3 PF02487.17 CDJ50742.1 - 0.085 11.9 13.5 0.089 11.8 13.5 1.1 1 0 0 1 1 1 0 CLN3 protein SelP_N PF04592.14 CDJ50742.1 - 0.086 12.2 18.6 0.093 12.1 18.6 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4446 PF14584.6 CDJ50742.1 - 0.087 12.8 9.9 0.1 12.5 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Ctr PF04145.15 CDJ50742.1 - 0.16 12.6 10.3 0.19 12.3 10.3 1.2 1 0 0 1 1 1 0 Ctr copper transporter family EOS1 PF12326.8 CDJ50742.1 - 0.19 11.7 11.1 0.22 11.4 11.1 1.2 1 0 0 1 1 1 0 N-glycosylation protein Velvet PF11754.8 CDJ50742.1 - 0.21 11.5 20.3 0.22 11.4 20.3 1.0 1 0 0 1 1 1 0 Velvet factor O-antigen_lig PF13425.6 CDJ50742.1 - 0.21 10.3 11.2 0.21 10.3 11.2 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CSG2 PF16965.5 CDJ50742.1 - 0.22 10.4 10.9 0.22 10.4 10.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF1980 PF09323.10 CDJ50742.1 - 0.23 11.4 12.7 0.25 11.2 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CobT PF06213.12 CDJ50742.1 - 0.23 10.8 30.1 0.25 10.7 30.1 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2561 PF10812.8 CDJ50742.1 - 0.28 11.2 1.2 0.32 11.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF4746 PF15928.5 CDJ50742.1 - 0.28 10.6 15.7 0.31 10.4 15.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Zip PF02535.22 CDJ50742.1 - 0.3 10.3 8.9 0.3 10.2 8.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pga1 PF10333.9 CDJ50742.1 - 0.34 10.8 6.9 0.56 10.0 6.9 1.4 1 1 0 1 1 1 0 GPI-Mannosyltransferase II co-activator YABBY PF04690.13 CDJ50742.1 - 0.38 11.3 19.4 0.42 11.2 19.4 1.1 1 0 0 1 1 1 0 YABBY protein Folate_carrier PF01770.18 CDJ50742.1 - 0.41 9.3 10.4 0.49 9.1 10.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier Nucleoside_tran PF01733.18 CDJ50742.1 - 0.43 9.9 7.9 0.5 9.7 7.9 1.1 1 0 0 1 1 1 0 Nucleoside transporter DUF913 PF06025.12 CDJ50742.1 - 0.52 9.2 14.2 0.56 9.1 14.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) UPF0560 PF10577.9 CDJ50742.1 - 0.6 8.5 30.4 0.62 8.5 30.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FPN1 PF06963.12 CDJ50742.1 - 0.67 8.4 9.4 0.85 8.1 9.4 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Bul1_N PF04425.12 CDJ50742.1 - 0.82 8.4 17.5 0.82 8.4 17.5 1.0 1 0 0 1 1 1 0 Bul1 N terminus DUF1682 PF07946.14 CDJ50742.1 - 0.85 8.8 18.1 0.88 8.7 18.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Peptidase_U57 PF05582.12 CDJ50742.1 - 0.99 8.6 15.3 1.1 8.5 15.3 1.1 1 0 0 1 1 1 0 YabG peptidase U57 TERB2 PF15101.6 CDJ50742.1 - 1.4 8.9 29.3 1.6 8.8 29.3 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3537 PF12056.8 CDJ50742.1 - 1.5 7.5 10.7 1.7 7.4 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) SpoIIP PF07454.11 CDJ50742.1 - 1.7 8.1 25.2 1.8 8.0 25.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Endostatin PF06482.11 CDJ50742.1 - 2.2 7.7 20.9 2.2 7.6 20.9 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PA26 PF04636.13 CDJ50742.1 - 2.2 7.1 18.0 2.5 6.9 18.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Otopetrin PF03189.13 CDJ50742.1 - 2.3 6.9 12.2 2.3 6.9 12.2 1.1 1 0 0 1 1 1 0 Otopetrin NEMP PF10225.9 CDJ50742.1 - 2.8 7.5 12.0 3.4 7.3 12.0 1.1 1 0 0 1 1 1 0 NEMP family TFB6 PF17110.5 CDJ50742.1 - 2.9 7.6 12.7 3.6 7.3 12.7 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4228 PF14009.6 CDJ50742.1 - 3 8.2 11.8 3.5 8.0 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Folliculin PF11704.8 CDJ50742.1 - 3.1 7.7 15.7 3.1 7.6 15.7 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport HCO3_cotransp PF00955.21 CDJ50742.1 - 3.1 6.5 11.9 3.4 6.4 11.9 1.0 1 0 0 1 1 1 0 HCO3- transporter family Scs3p PF10261.9 CDJ50742.1 - 3.2 7.2 13.2 5.3 6.5 13.2 1.4 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Pannexin_like PF12534.8 CDJ50742.1 - 3.2 6.7 18.6 3.5 6.6 18.6 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 CCDC53 PF10152.9 CDJ50742.1 - 3.2 8.1 23.8 3.7 7.9 23.8 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CPSF100_C PF13299.6 CDJ50742.1 - 4 7.6 20.2 4.5 7.4 20.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Paf1 PF03985.13 CDJ50742.1 - 4.1 6.3 26.7 4.5 6.2 26.7 1.0 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 CDJ50742.1 - 4.2 7.1 26.5 4.7 7.0 26.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PIP5K PF01504.18 CDJ50742.1 - 4.3 6.5 18.7 4.4 6.4 18.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase MMR1 PF08505.10 CDJ50742.1 - 5 7.3 29.4 6.1 7.0 29.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF2828 PF11443.8 CDJ50742.1 - 5.8 4.9 23.8 6.2 4.8 23.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Mem_trans PF03547.18 CDJ50742.1 - 7.4 4.8 9.6 8.2 4.7 9.6 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4834 PF16118.5 CDJ50742.1 - 8.8 7.4 31.9 1.4e+02 3.5 31.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) PepSY_TM_like_2 PF16357.5 CDJ50742.1 - 9.2 6.2 12.1 11 6.0 12.1 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like Endonuc_Holl PF10107.9 CDJ50742.1 - 9.7 6.0 17.0 10 5.9 17.0 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase SUIM_assoc PF16619.5 CDJ50743.1 - 1.9 8.6 8.2 0.31 11.1 1.9 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Jun PF03957.13 CDJ50743.1 - 4.4 7.1 12.7 5.2 6.9 12.7 1.0 1 0 0 1 1 1 0 Jun-like transcription factor Tic110 PF16940.5 CDJ50743.1 - 6.9 5.0 14.6 7.8 4.8 14.6 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter V-ATPase_C PF03223.15 CDJ50744.1 - 2.1e-91 307.1 0.0 2.3e-91 307.0 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C COG2 PF06148.11 CDJ50744.1 - 0.14 12.2 1.0 0.32 11.1 0.3 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ATP-synt_ab PF00006.25 CDJ50745.1 - 2.7e-61 206.9 0.0 4e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDJ50745.1 - 1.5e-18 67.0 3.0 6.4e-18 65.0 3.0 2.0 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RnfC_N PF13375.6 CDJ50745.1 - 0.00044 20.2 0.2 0.0012 18.8 0.2 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain AAA_16 PF13191.6 CDJ50745.1 - 0.0029 18.0 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CDJ50745.1 - 0.0049 17.3 0.0 0.44 11.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CDJ50745.1 - 0.012 14.9 0.3 0.024 13.8 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain T3SS_ATPase_C PF18269.1 CDJ50745.1 - 0.029 14.2 0.8 0.16 11.9 0.8 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase PF06745.13 CDJ50745.1 - 0.029 13.7 1.6 0.048 13.0 0.4 1.9 2 0 0 2 2 2 0 KaiC RsgA_GTPase PF03193.16 CDJ50745.1 - 0.074 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 CDJ50745.1 - 0.14 12.1 0.6 0.48 10.3 0.1 2.1 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 CDJ50745.1 - 0.14 12.5 0.9 0.33 11.3 0.2 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CDJ50745.1 - 0.56 10.7 2.6 0.48 10.9 0.1 2.0 2 0 0 2 2 2 0 ABC transporter Exonuc_VII_L PF02601.15 CDJ50746.1 - 1.1 8.7 34.4 0.095 12.2 24.6 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4207 PF13904.6 CDJ50748.1 - 0.014 15.1 10.6 0.014 15.1 10.6 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4207) DUF5327 PF17261.2 CDJ50748.1 - 0.036 14.8 10.2 0.036 14.8 10.2 4.0 2 1 0 2 2 2 0 Family of unknown function (DUF5327) DUF2052 PF09747.9 CDJ50748.1 - 5.3 7.1 42.0 0.68 10.0 4.9 3.0 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) NOP5NT PF08156.13 CDJ50750.1 - 5e-13 49.2 2.0 5.4e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain SDA1 PF05285.12 CDJ50750.1 - 0.0013 18.3 7.8 0.0016 17.9 7.8 1.1 1 0 0 1 1 1 1 SDA1 Pol_alpha_B_N PF08418.10 CDJ50750.1 - 0.005 16.8 6.3 0.059 13.3 0.2 2.1 2 0 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal Nop PF01798.18 CDJ50750.1 - 0.008 15.7 1.8 0.013 15.0 1.8 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Presenilin PF01080.17 CDJ50750.1 - 0.056 12.2 8.9 0.074 11.8 8.9 1.3 1 0 0 1 1 1 0 Presenilin RAB3GAP2_N PF14655.6 CDJ50750.1 - 0.26 10.5 11.1 0.4 9.9 10.9 1.3 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Eapp_C PF10238.9 CDJ50750.1 - 0.38 10.8 9.3 2.6 8.1 0.9 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Spt20 PF12090.8 CDJ50750.1 - 1.6 8.3 19.6 1.4 8.5 9.5 2.2 2 0 0 2 2 2 0 Spt20 family GREB1 PF15782.5 CDJ50750.1 - 2.6 5.1 19.7 3.3 4.7 19.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ANAPC_CDC26 PF10471.9 CDJ50750.1 - 3.1 8.7 23.6 0.4 11.5 7.8 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Miff PF05644.11 CDJ50750.1 - 3.1 7.3 13.3 4.8 6.7 13.3 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff SUIM_assoc PF16619.5 CDJ50750.1 - 3.7 7.7 23.9 1.8 8.7 12.8 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 CDJ50750.1 - 4.8 8.2 14.7 12 6.9 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RMP PF14996.6 CDJ50750.1 - 9 6.5 13.8 7.1 6.8 1.8 2.3 2 0 0 2 2 2 0 Retinal Maintenance Otopetrin PF03189.13 CDJ50751.1 - 0.00024 20.0 4.3 9.4 4.9 0.0 5.2 4 2 0 4 4 4 1 Otopetrin DUF2632 PF10943.8 CDJ50751.1 - 1.5 8.4 4.4 15 5.1 4.4 2.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) Spt20 PF12090.8 CDJ50752.1 - 0.00093 18.9 10.2 0.00093 18.9 10.2 14.8 9 5 1 11 11 11 2 Spt20 family RskA PF10099.9 CDJ50752.1 - 0.0069 16.7 0.0 0.0069 16.7 0.0 20.0 6 5 11 17 17 17 4 Anti-sigma-K factor rskA PAP1 PF08601.10 CDJ50752.1 - 0.21 11.3 0.0 0.21 11.3 0.0 9.8 4 3 5 10 10 10 0 Transcription factor PAP1 Kinesin PF00225.23 CDJ50753.1 - 8.1e-21 74.3 1.9 8.1e-21 74.3 1.9 5.5 5 2 0 5 5 5 1 Kinesin motor domain Sporozoite_P67 PF05642.11 CDJ50754.1 - 1.7 6.7 5.2 2 6.4 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRM_1 PF00076.22 CDJ50756.1 - 1.4e-16 60.1 0.0 1e-07 31.6 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ50756.1 - 0.016 15.0 0.0 4.7 7.1 0.0 2.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif BRAP2 PF07576.12 CDJ50756.1 - 0.19 12.0 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 SR-25 PF10500.9 CDJ50758.1 - 0.069 12.8 4.0 0.08 12.5 4.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Draxin PF15550.6 CDJ50758.1 - 1.5 8.6 9.6 1.6 8.5 9.6 1.1 1 0 0 1 1 1 0 Draxin ACDC PF14733.6 CDJ50759.1 - 3.2e-09 37.0 10.9 2.4e-08 34.2 10.9 2.5 1 1 0 1 1 1 1 AP2-coincident C-terminal Spt20 PF12090.8 CDJ50759.1 - 2.2e-05 24.2 2.5 2.2e-05 24.2 2.5 8.0 6 2 2 8 8 8 1 Spt20 family SUIM_assoc PF16619.5 CDJ50759.1 - 0.0071 16.4 2.7 0.0071 16.4 2.7 8.9 7 2 1 8 8 8 2 Unstructured region C-term to UIM in Ataxin3 SNF2_N PF00176.23 CDJ50762.1 - 2.4e-09 36.4 1.9 2.4e-09 36.4 1.9 2.4 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ50762.1 - 1.6e-08 34.9 0.0 5.7e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Adipogenin PF15202.6 CDJ50763.1 - 0.28 11.2 3.9 1.4 9.0 3.9 2.3 1 0 0 1 1 1 0 Adipogenin SRTM1 PF15872.5 CDJ50763.1 - 1.8 8.7 11.5 3.3 7.9 11.5 1.4 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 Caldesmon PF02029.15 CDJ50763.1 - 8.5 5.0 75.6 9.6 4.8 75.6 1.0 1 0 0 1 1 1 0 Caldesmon Med15 PF09606.10 CDJ50764.1 - 0.4 9.3 59.4 0.5 9.0 59.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2339 PF10101.9 CDJ50764.1 - 0.91 8.0 27.8 1 7.8 27.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) SNF2_N PF00176.23 CDJ50765.1 - 1.8e-05 23.7 0.0 2.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2722 PF10846.8 CDJ50766.1 - 0.0059 15.6 16.1 0.0079 15.2 16.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF1645 PF07816.11 CDJ50766.1 - 0.0082 16.7 6.5 0.011 16.3 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) SLD3 PF08639.10 CDJ50766.1 - 0.042 12.6 6.1 0.051 12.3 6.1 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 TFIIA PF03153.13 CDJ50766.1 - 0.086 12.8 18.5 0.1 12.6 18.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MPM1 PF17234.2 CDJ50766.1 - 0.087 13.1 8.2 0.14 12.4 8.2 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Presenilin PF01080.17 CDJ50766.1 - 0.14 10.9 5.1 0.16 10.7 5.1 1.1 1 0 0 1 1 1 0 Presenilin Androgen_recep PF02166.16 CDJ50766.1 - 0.15 10.8 17.5 0.21 10.4 17.5 1.3 1 0 0 1 1 1 0 Androgen receptor LCD1 PF09798.9 CDJ50766.1 - 0.19 10.2 4.5 0.21 10.1 4.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4770 PF15994.5 CDJ50766.1 - 0.26 11.5 8.0 0.35 11.1 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4175 PF13779.6 CDJ50766.1 - 0.31 8.9 13.5 0.33 8.8 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) V_ATPase_I PF01496.19 CDJ50766.1 - 0.32 8.9 6.6 0.39 8.6 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GREB1 PF15782.5 CDJ50766.1 - 0.4 7.7 8.0 0.45 7.6 8.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Med15 PF09606.10 CDJ50766.1 - 0.42 9.2 16.2 0.5 9.0 16.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CobT PF06213.12 CDJ50766.1 - 0.78 9.1 8.7 1 8.7 8.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peptidase_S64 PF08192.11 CDJ50766.1 - 1 7.7 9.3 1.2 7.5 9.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Suf PF05843.14 CDJ50766.1 - 2.8 7.9 9.9 3.5 7.5 9.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Apt1 PF10351.9 CDJ50766.1 - 3.1 6.5 10.2 3.9 6.2 10.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Orf78 PF06024.12 CDJ50766.1 - 4 7.8 5.0 7.7 6.9 5.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Lin-8 PF03353.15 CDJ50766.1 - 4.5 6.7 13.3 6.1 6.3 13.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3270 PF11674.8 CDJ50766.1 - 4.9 7.4 9.9 8.1 6.7 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) RR_TM4-6 PF06459.12 CDJ50766.1 - 7.9 6.2 9.7 11 5.7 9.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ER PF01133.17 CDJ50767.1 - 2.3e-25 88.4 0.0 2.6e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Jun PF03957.13 CDJ50768.1 - 0.0081 16.1 5.6 0.009 15.9 5.6 1.0 1 0 0 1 1 1 1 Jun-like transcription factor CP12 PF02672.15 CDJ50768.1 - 0.021 15.6 0.9 0.021 15.6 0.9 2.7 2 1 0 2 2 1 0 CP12 domain DUF1635 PF07795.11 CDJ50768.1 - 0.14 12.0 13.8 0.17 11.8 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Neuraminidase PF18413.1 CDJ50768.1 - 0.15 11.7 11.1 0.2 11.3 11.1 1.1 1 0 0 1 1 1 0 Neuraminidase-like domain MAT1 PF06391.13 CDJ50768.1 - 0.3 10.9 14.4 0.42 10.4 14.4 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 INSIG PF07281.12 CDJ50768.1 - 1.6 8.3 4.0 2.3 7.8 4.0 1.3 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) DUF4667 PF15700.5 CDJ50768.1 - 1.6 8.8 13.7 2.1 8.4 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) MMR1 PF08505.10 CDJ50768.1 - 1.6 8.9 16.7 2 8.6 16.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein K_trans PF02705.16 CDJ50768.1 - 3.5 6.0 4.3 4.2 5.8 4.3 1.0 1 0 0 1 1 1 0 K+ potassium transporter XRN_M PF17846.1 CDJ50768.1 - 4.4 6.2 8.9 4.8 6.0 8.9 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Presenilin PF01080.17 CDJ50768.1 - 5.1 5.8 17.0 5.8 5.6 17.0 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ50768.1 - 8.4 6.3 10.0 11 6.0 10.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A VIT1 PF01988.19 CDJ50768.1 - 8.5 6.2 6.4 11 5.8 6.4 1.2 1 0 0 1 1 1 0 VIT family G0-G1_switch_2 PF15103.6 CDJ50768.1 - 9.1 6.8 10.4 33 5.0 0.1 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 Peptidase_M20 PF01546.28 CDJ50770.1 - 2.2e-29 102.7 0.1 3.7e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDJ50770.1 - 5.2e-11 42.4 0.0 1.3e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain ATPase_2 PF01637.18 CDJ50771.1 - 0.0016 18.4 0.1 0.075 12.9 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CDJ50771.1 - 0.0032 18.0 0.1 0.005 17.4 0.1 1.4 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 CDJ50771.1 - 0.0041 17.1 0.0 0.0075 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CDJ50771.1 - 0.0093 16.2 0.2 0.04 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CDJ50771.1 - 0.01 16.3 0.0 0.04 14.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDJ50771.1 - 0.01 16.4 0.0 0.02 15.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ50771.1 - 0.015 15.7 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 CDJ50771.1 - 0.037 13.9 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 NTPase KAP_NTPase PF07693.14 CDJ50771.1 - 0.041 13.1 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.6 CDJ50771.1 - 0.054 14.0 0.4 0.27 11.7 0.2 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CDJ50771.1 - 0.069 13.5 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 CDJ50771.1 - 0.071 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CDJ50771.1 - 0.087 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 NACHT domain MobB PF03205.14 CDJ50771.1 - 0.089 12.7 0.1 0.24 11.3 0.1 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 CDJ50771.1 - 0.098 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CDJ50771.1 - 0.1 12.3 0.2 0.27 10.9 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 CDJ50771.1 - 0.11 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CoaE PF01121.20 CDJ50771.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase Rad17 PF03215.15 CDJ50771.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 CDJ50771.1 - 0.2 11.5 0.2 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ribosomal_L16 PF00252.18 CDJ50772.1 - 3.8e-37 127.2 0.0 4.7e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e BCAS2 PF05700.11 CDJ50773.1 - 1.2e-43 149.3 5.0 1.8e-43 148.7 5.0 1.3 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) HAUS6_N PF14661.6 CDJ50773.1 - 1.2 8.6 6.9 8.3 5.9 6.9 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TMF_TATA_bd PF12325.8 CDJ50773.1 - 5.1 7.3 10.2 0.17 12.1 4.2 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2973 PF11189.8 CDJ50774.1 - 1 9.5 3.9 0.4 10.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Spt20 PF12090.8 CDJ50774.1 - 1.8 8.2 23.2 2.1 7.9 12.4 2.3 2 0 0 2 2 2 0 Spt20 family Podoplanin PF05808.11 CDJ50775.1 - 3.9 7.6 7.0 3.1 7.9 5.8 1.4 1 1 0 1 1 1 0 Podoplanin PIG-L PF02585.17 CDJ50776.1 - 5.5e-13 49.7 0.1 4.3e-12 46.8 0.0 2.3 2 1 0 2 2 2 1 GlcNAc-PI de-N-acetylase Saw1 PF11561.8 CDJ50776.1 - 0.0028 17.2 2.8 0.0041 16.7 2.8 1.2 1 0 0 1 1 1 1 Single strand annealing-weakened 1 Exonuc_VII_L PF02601.15 CDJ50776.1 - 0.046 13.3 9.7 0.077 12.6 9.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit CLN3 PF02487.17 CDJ50776.1 - 0.26 10.3 3.5 0.53 9.3 3.5 1.5 1 0 0 1 1 1 0 CLN3 protein SLC12 PF03522.15 CDJ50776.1 - 0.54 9.2 14.3 1.1 8.2 14.3 1.5 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 CDJ50776.1 - 1.5 7.3 30.8 0.032 12.8 17.0 2.3 2 0 0 2 2 2 0 Macoilin family DUF4407 PF14362.6 CDJ50776.1 - 3.2 7.0 14.5 5 6.4 14.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SR-25 PF10500.9 CDJ50778.1 - 0.0037 16.9 3.4 0.0037 16.9 3.4 4.8 4 1 0 4 4 4 1 Nuclear RNA-splicing-associated protein CDC37_N PF03234.14 CDJ50778.1 - 0.039 14.9 0.8 0.039 14.9 0.8 4.7 4 1 0 4 4 4 0 Cdc37 N terminal kinase binding TatD_DNase PF01026.21 CDJ50778.1 - 0.052 12.9 5.0 0.92 8.8 0.1 3.4 1 1 2 3 3 3 0 TatD related DNase Presenilin PF01080.17 CDJ50778.1 - 0.56 8.9 25.3 0.42 9.3 15.6 2.4 2 0 0 2 2 2 0 Presenilin Tubulin_C PF03953.17 CDJ50778.1 - 0.75 10.0 3.1 2.3 8.4 0.0 2.4 2 1 0 2 2 2 0 Tubulin C-terminal domain DUF3446 PF11928.8 CDJ50778.1 - 2.8 8.3 56.3 0.24 11.7 9.0 5.0 5 0 0 5 5 5 0 Early growth response N-terminal domain COX2 PF00116.20 CDJ50779.1 - 2.3e-43 146.9 0.0 3.5e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain RskA PF10099.9 CDJ50779.1 - 0.0035 17.7 6.6 0.0035 17.7 6.6 2.2 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ50779.1 - 0.0055 15.7 2.3 0.0055 15.7 2.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ50779.1 - 0.029 14.0 29.4 0.16 11.6 8.8 2.1 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 CDJ50779.1 - 0.034 14.2 8.6 0.034 14.2 8.6 2.7 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spore_YhcN_YlaJ PF09580.10 CDJ50779.1 - 0.057 13.5 0.8 0.084 13.0 0.8 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) EPL1 PF10513.9 CDJ50779.1 - 0.33 11.3 4.5 2.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like SR-25 PF10500.9 CDJ50779.1 - 0.61 9.7 18.5 1.2 8.7 18.5 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ50779.1 - 0.88 8.3 10.6 1.1 7.9 10.6 1.1 1 0 0 1 1 1 0 Presenilin TLV_coat PF00429.19 CDJ50779.1 - 1 8.0 7.6 1.3 7.6 7.6 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) DUF4400 PF14348.6 CDJ50779.1 - 1.7 8.1 4.3 3.3 7.2 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Shadoo PF14999.6 CDJ50779.1 - 1.9 8.6 10.0 37 4.4 7.9 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Apt1 PF10351.9 CDJ50779.1 - 2.1 7.1 7.0 2.7 6.7 7.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nha1_C PF08619.10 CDJ50779.1 - 3.9 6.6 14.1 14 4.8 14.4 1.6 1 1 1 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4770 PF15994.5 CDJ50779.1 - 7.2 6.8 12.8 0.4 10.9 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) AUX_IAA PF02309.16 CDJ50779.1 - 7.6 6.3 9.1 12 5.7 9.1 1.2 1 0 0 1 1 1 0 AUX/IAA family Suf PF05843.14 CDJ50780.1 - 0.0098 15.9 2.2 0.0082 16.2 2.2 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) SAGA-Tad1 PF12767.7 CDJ50780.1 - 0.013 15.3 7.3 0.022 14.5 7.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CLN3 PF02487.17 CDJ50780.1 - 0.064 12.3 0.1 0.079 12.0 0.1 1.1 1 0 0 1 1 1 0 CLN3 protein eIF_4EBP PF05456.11 CDJ50780.1 - 0.072 13.0 5.2 0.12 12.3 5.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Spt20 PF12090.8 CDJ50780.1 - 0.33 10.5 19.0 0.49 10.0 19.0 1.2 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ50780.1 - 0.76 8.7 24.1 1.2 8.0 24.1 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Mucin PF01456.17 CDJ50780.1 - 0.77 9.7 5.9 0.15 12.1 1.5 2.2 2 1 0 2 2 2 0 Mucin-like glycoprotein DUF3446 PF11928.8 CDJ50780.1 - 1.7 9.0 20.2 2.7 8.4 10.8 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Keratin_2_head PF16208.5 CDJ50781.1 - 1.1 9.4 14.5 1.3 9.1 14.5 1.3 1 0 0 1 1 1 0 Keratin type II head Sporozoite_P67 PF05642.11 CDJ50781.1 - 8.6 4.3 8.3 8.2 4.4 8.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med15 PF09606.10 CDJ50782.1 - 0.036 12.8 3.3 0.036 12.8 3.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal EF-hand_7 PF13499.6 CDJ50782.1 - 0.082 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair USP8_interact PF08941.10 CDJ50782.1 - 0.14 11.9 2.9 0.19 11.6 2.9 1.1 1 0 0 1 1 1 0 USP8 interacting Activator_LAG-3 PF11498.8 CDJ50782.1 - 2.1 7.2 13.0 2.3 7.1 13.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SPT2 PF08243.11 CDJ50783.1 - 1.5e-06 28.7 13.9 1.5e-06 28.7 13.9 6.6 6 2 0 6 6 6 1 SPT2 chromatin protein Shadoo PF14999.6 CDJ50783.1 - 9.7 6.3 32.2 1.5 8.9 13.4 3.9 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective Surface_antigen PF11054.8 CDJ50784.1 - 6.6e-24 84.9 19.9 1.6e-13 50.9 6.6 4.3 3 2 0 3 3 3 3 Sporozoite TA4 surface antigen DUF3334 PF11813.8 CDJ50784.1 - 0.11 12.2 1.1 0.18 11.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) PDT PF00800.18 CDJ50785.1 - 0.71 9.6 0.0 0.71 9.6 0.0 2.8 3 1 1 4 4 4 0 Prephenate dehydratase Surface_antigen PF11054.8 CDJ50786.1 - 3.6e-18 66.1 7.5 3.9e-12 46.4 2.4 4.6 2 2 1 3 3 3 3 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ50787.1 - 9.3e-25 87.7 11.1 2e-11 44.0 2.6 5.3 1 1 2 3 3 3 3 Sporozoite TA4 surface antigen Sec16_C PF12931.7 CDJ50789.1 - 1.2e-13 51.4 10.5 1.2e-13 51.4 10.5 3.7 3 2 0 3 3 3 1 Sec23-binding domain of Sec16 CytochromB561_N PF09786.9 CDJ50789.1 - 0.0036 16.4 5.9 0.0036 16.4 5.9 3.3 3 0 0 3 3 3 2 Cytochrome B561, N terminal PAP_central PF04928.17 CDJ50789.1 - 0.011 14.7 0.1 0.011 14.7 0.1 2.6 3 0 0 3 3 3 0 Poly(A) polymerase central domain DUF1645 PF07816.11 CDJ50790.1 - 0.0013 19.3 1.7 0.0013 19.3 1.7 6.6 4 2 1 5 5 5 1 Protein of unknown function (DUF1645) Presenilin PF01080.17 CDJ50790.1 - 0.0015 17.4 3.8 0.0015 17.4 3.8 5.6 4 1 1 5 5 5 3 Presenilin N6_N4_Mtase PF01555.18 CDJ50790.1 - 0.014 15.1 0.1 5.4 6.7 0.0 4.1 3 1 0 3 3 3 0 DNA methylase AF-4 PF05110.13 CDJ50790.1 - 1.5 6.9 139.2 0.033 12.3 58.8 4.2 4 0 0 4 4 4 0 AF-4 proto-oncoprotein Miga PF10265.9 CDJ50791.1 - 0.23 10.4 1.7 0.25 10.3 1.7 1.0 1 0 0 1 1 1 0 Mitoguardin NUDE_C PF04880.13 CDJ50791.1 - 4.2 7.8 12.9 5.3 7.5 12.9 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region SAPS PF04499.15 CDJ50792.1 - 0.2 10.4 29.2 0.13 11.0 7.0 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Peptidase_S9 PF00326.21 CDJ50793.1 - 3.2e-11 43.1 0.2 3.2e-11 43.1 0.2 2.9 2 2 0 2 2 2 1 Prolyl oligopeptidase family SUIM_assoc PF16619.5 CDJ50793.1 - 0.0025 17.9 0.6 0.0025 17.9 0.6 19.2 5 3 2 7 7 7 2 Unstructured region C-term to UIM in Ataxin3 DUF2076 PF09849.9 CDJ50793.1 - 0.0075 16.3 15.1 0.0075 16.3 15.1 10.3 5 2 2 7 7 7 3 Uncharacterized protein conserved in bacteria (DUF2076) DUF5308 PF17233.2 CDJ50793.1 - 0.0093 16.2 4.1 0.0093 16.2 4.1 8.4 4 2 1 5 5 5 2 Family of unknown function (DUF5308) SARAF PF06682.12 CDJ50793.1 - 0.011 15.4 1.5 0.011 15.4 1.5 7.5 3 2 2 5 5 5 0 SOCE-associated regulatory factor of calcium homoeostasis Orf78 PF06024.12 CDJ50793.1 - 0.037 14.3 0.4 0.037 14.3 0.4 9.3 7 1 0 7 7 7 0 Orf78 (ac78) Peroxin-13_N PF04088.13 CDJ50793.1 - 0.048 14.0 0.1 0.048 14.0 0.1 9.0 6 1 1 7 7 7 0 Peroxin 13, N-terminal region RAB3GAP2_C PF14656.6 CDJ50793.1 - 0.054 11.7 0.1 0.054 11.7 0.1 6.5 4 1 1 5 5 5 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Aminotran_4 PF01063.19 CDJ50793.1 - 0.63 9.9 0.0 0.63 9.9 0.0 2.5 2 1 0 2 2 2 0 Amino-transferase class IV PRP21_like_P PF12230.8 CDJ50794.1 - 5.1e-39 134.4 6.0 5.1e-39 134.4 6.0 2.3 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CDJ50794.1 - 5e-08 32.8 0.1 1.5e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 Surp module DASH_Spc34 PF08657.10 CDJ50794.1 - 0.00037 20.4 6.4 0.00088 19.1 6.4 1.5 1 0 0 1 1 1 1 DASH complex subunit Spc34 RNA_pol_3_Rpc31 PF11705.8 CDJ50794.1 - 9.8 6.4 16.3 39 4.4 16.3 1.9 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRM_1 PF00076.22 CDJ50795.1 - 1.5e-15 56.7 0.0 0.00018 21.3 0.0 4.6 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DOPA_dioxygen PF08883.11 CDJ50795.1 - 0.029 14.5 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Dopa 4,5-dioxygenase family cNMP_binding PF00027.29 CDJ50796.1 - 1.8e-80 265.1 2.2 1.6e-18 66.5 0.0 6.6 6 0 0 6 6 6 6 Cyclic nucleotide-binding domain EF-hand_8 PF13833.6 CDJ50796.1 - 0.0031 17.3 0.1 1.2 9.1 0.1 3.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ50796.1 - 0.0047 16.4 0.7 0.1 12.2 0.1 3.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CDJ50796.1 - 0.01 15.7 0.9 0.25 11.3 0.1 3.4 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.6 CDJ50796.1 - 0.059 13.8 7.7 0.48 10.9 0.0 5.3 6 0 0 6 6 6 0 EF-hand domain pair Phosphodiest PF01663.22 CDJ50798.1 - 0.0097 15.5 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Baculo_PEP_C PF04513.12 CDJ50799.1 - 0.35 10.9 6.6 0.6 10.2 2.8 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pox_A_type_inc PF04508.12 CDJ50799.1 - 1.5 8.8 11.6 0.095 12.6 0.4 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat zf-RING_2 PF13639.6 CDJ50800.1 - 8e-12 45.3 9.2 1.3e-11 44.6 9.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDJ50800.1 - 3.1e-10 39.6 6.1 6.5e-10 38.6 6.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDJ50800.1 - 9.7e-08 31.8 7.7 1.5e-07 31.2 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ50800.1 - 1.6e-06 27.8 8.3 2.7e-06 27.1 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ50800.1 - 5.1e-06 26.4 2.0 9.7e-06 25.6 2.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CDJ50800.1 - 1.2e-05 25.5 9.3 3.4e-05 24.0 9.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDJ50800.1 - 1.7e-05 24.7 6.3 3e-05 23.9 6.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CDJ50800.1 - 8.1e-05 22.2 4.7 0.00014 21.5 4.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CDJ50800.1 - 8.5e-05 22.4 6.4 0.00013 21.9 6.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDJ50800.1 - 0.00059 19.6 5.2 0.00083 19.2 5.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CDJ50800.1 - 0.00097 18.9 2.6 0.0024 17.6 2.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 CDJ50800.1 - 0.035 14.2 7.6 0.073 13.2 7.6 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 CDJ50800.1 - 0.046 13.6 7.5 0.083 12.8 7.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CDJ50800.1 - 0.05 13.8 5.3 0.11 12.7 5.3 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 CDJ50800.1 - 0.084 13.2 6.3 0.14 12.5 6.3 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 CDJ50800.1 - 0.26 11.5 7.8 1.4 9.2 7.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 CDJ50800.1 - 1.2 9.1 5.7 1.8 8.5 5.7 1.3 1 0 0 1 1 1 0 PHD-finger C2 PF00168.30 CDJ50801.1 - 1.1e-28 99.6 0.1 2.1e-05 24.8 0.1 7.0 7 0 0 7 7 7 6 C2 domain Ferlin_C PF16165.5 CDJ50801.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Ferlin C-terminus FerI PF08151.12 CDJ50801.1 - 0.16 12.1 0.0 0.79 9.9 0.0 2.0 2 0 0 2 2 2 0 FerI (NUC094) domain DNA_pol_E_B PF04042.16 CDJ50802.1 - 8.6e-20 71.0 2.6 3.3e-19 69.1 0.9 2.5 2 1 1 3 3 3 1 DNA polymerase alpha/epsilon subunit B PAS_2 PF08446.11 CDJ50803.1 - 0.22 12.2 2.6 0.45 11.2 0.2 2.8 2 0 0 2 2 2 0 PAS fold NLRC4_HD PF17889.1 CDJ50803.1 - 1.1 9.6 4.7 0.44 10.9 0.2 2.9 2 0 0 2 2 2 0 NLRC4 helical domain DUF3223 PF11523.8 CDJ50804.1 - 0.19 12.6 0.0 0.3 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3223) Fis1_TPR_C PF14853.6 CDJ50805.1 - 4.5e-16 58.7 0.2 9.5e-16 57.6 0.2 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CDJ50805.1 - 3.3e-05 23.4 0.0 5.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 CDJ50805.1 - 0.00021 21.2 0.3 0.0019 18.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ50805.1 - 0.0052 17.4 0.5 0.026 15.2 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ50805.1 - 0.025 15.1 0.1 0.044 14.3 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ50805.1 - 0.04 14.1 0.2 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ50805.1 - 0.078 13.7 0.7 0.28 11.9 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 CDJ50806.1 - 5.7e-89 299.0 17.3 1.2e-88 297.9 17.3 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family dsDNA_bind PF01984.20 CDJ50807.1 - 1.4e-20 73.6 8.3 1.7e-20 73.3 8.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain MAS20 PF02064.15 CDJ50807.1 - 0.0042 17.2 1.4 0.006 16.7 1.4 1.2 1 0 0 1 1 1 1 MAS20 protein import receptor Lipase_chap PF03280.14 CDJ50807.1 - 0.028 14.4 9.2 0.025 14.5 7.7 1.6 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein DUF4953 PF16313.5 CDJ50807.1 - 0.085 12.1 1.1 0.1 11.8 1.1 1.1 1 0 0 1 1 1 0 Met-zincin DivIC PF04977.15 CDJ50807.1 - 0.69 9.7 7.5 1.1 9.1 7.5 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF3886 PF13025.6 CDJ50807.1 - 2.1 8.6 11.5 3 8.1 10.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3886) CHD5 PF04420.14 CDJ50808.1 - 2.5e-06 27.5 4.9 2.5e-06 27.5 4.9 1.5 2 0 0 2 2 2 1 CHD5-like protein CAP59_mtransfer PF11735.8 CDJ50808.1 - 0.16 11.6 1.5 0.25 11.0 1.5 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 cNMP_binding PF00027.29 CDJ50809.1 - 1.4e-10 41.0 0.1 1.4e-05 25.1 0.0 4.0 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Eryth_link_C PF16915.5 CDJ50809.1 - 0.088 12.8 0.1 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 Annelid erythrocruorin linker subunit C-terminus RAP1 PF07218.11 CDJ50810.1 - 0.0073 14.7 2.9 0.011 14.0 2.9 1.2 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Dpy-30 PF05186.13 CDJ50810.1 - 0.51 10.1 0.0 0.51 10.1 0.0 2.8 3 0 0 3 3 3 0 Dpy-30 motif Proteasome PF00227.26 CDJ50814.1 - 3.7e-37 127.7 0.0 1.2e-36 126.0 0.0 1.8 1 1 0 1 1 1 1 Proteasome subunit DUF3498 PF12004.8 CDJ50815.1 - 0.7 9.0 10.8 0.78 8.9 10.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) AAA_19 PF13245.6 CDJ50816.1 - 0.065 13.6 0.8 3.2 8.1 0.1 2.2 1 1 0 2 2 2 0 AAA domain Motilin_assoc PF04643.12 CDJ50816.1 - 0.065 13.1 1.5 16 5.4 0.1 3.5 2 1 1 3 3 3 0 Motilin/ghrelin-associated peptide FeThRed_A PF02941.15 CDJ50816.1 - 0.069 13.3 0.0 25 5.1 0.0 3.5 3 1 1 4 4 4 0 Ferredoxin thioredoxin reductase variable alpha chain T2SSE PF00437.20 CDJ50816.1 - 0.28 10.2 1.4 48 2.9 0.0 3.2 3 1 0 4 4 4 0 Type II/IV secretion system protein NAM-associated PF14303.6 CDJ50817.1 - 0.55 10.9 0.0 0.55 10.9 0.0 8.6 4 2 4 9 9 9 0 No apical meristem-associated C-terminal domain Vps35 PF03635.17 CDJ50818.1 - 1.5e-76 258.5 0.7 1.8e-76 258.3 0.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF3138 PF11336.8 CDJ50818.1 - 0.18 10.4 7.1 0.23 10.0 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RNA_pol_Rpb2_6 PF00562.28 CDJ50819.1 - 4.1e-54 184.1 0.0 1.4e-34 119.8 0.0 2.4 2 1 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_4 PF04566.13 CDJ50819.1 - 1.1e-20 73.7 0.5 1.1e-20 73.7 0.5 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_1 PF04563.15 CDJ50819.1 - 1.8e-20 73.3 0.0 2.8e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CDJ50819.1 - 4.3e-19 68.5 0.0 8.1e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 CDJ50819.1 - 1.4e-14 54.2 0.0 1.3e-08 34.7 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 CDJ50819.1 - 2.4e-07 31.2 0.3 5.2e-07 30.1 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 SUIM_assoc PF16619.5 CDJ50820.1 - 0.019 15.0 13.4 0.065 13.3 7.2 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CAMSAP_CC1 PF17095.5 CDJ50820.1 - 9.8 6.1 14.9 1.1 9.2 0.9 2.8 3 0 0 3 3 3 0 Spectrin-binding region of Ca2+-Calmodulin ADK PF00406.22 CDJ50821.1 - 0.0002 21.5 0.5 0.34 11.0 0.2 3.4 3 0 0 3 3 3 1 Adenylate kinase RskA PF10099.9 CDJ50821.1 - 0.00028 21.3 10.3 0.00028 21.3 10.3 4.1 2 1 1 3 3 1 1 Anti-sigma-K factor rskA AAA_33 PF13671.6 CDJ50821.1 - 0.00047 20.3 0.9 0.00047 20.3 0.9 3.6 2 1 1 3 3 2 1 AAA domain AAA_18 PF13238.6 CDJ50821.1 - 0.0026 18.3 5.3 0.0037 17.8 0.0 3.1 3 1 1 4 4 4 1 AAA domain Spt20 PF12090.8 CDJ50821.1 - 0.0051 16.5 50.6 0.016 14.8 0.6 4.2 4 0 0 4 4 4 3 Spt20 family AAA PF00004.29 CDJ50821.1 - 0.011 16.1 0.1 0.067 13.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SUIM_assoc PF16619.5 CDJ50821.1 - 0.012 15.7 1.1 0.012 15.7 1.1 6.2 4 2 1 5 5 4 0 Unstructured region C-term to UIM in Ataxin3 SKI PF01202.22 CDJ50821.1 - 0.021 15.0 5.0 0.26 11.4 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase AAA_17 PF13207.6 CDJ50821.1 - 0.025 15.0 0.2 0.025 15.0 0.2 3.8 4 1 0 4 4 2 0 AAA domain AAA_5 PF07728.14 CDJ50821.1 - 0.027 14.5 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ50821.1 - 0.08 13.2 2.4 0.78 10.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CDJ50821.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Thymidylate_kin PF02223.17 CDJ50821.1 - 0.23 11.1 6.9 15 5.2 0.0 3.1 2 1 1 3 3 3 0 Thymidylate kinase ABC_tran PF00005.27 CDJ50821.1 - 0.28 11.7 0.0 0.28 11.7 0.0 3.0 4 0 0 4 4 3 0 ABC transporter RSRP PF17069.5 CDJ50821.1 - 0.46 10.0 35.0 0.11 12.0 18.4 2.6 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 AAA_28 PF13521.6 CDJ50821.1 - 0.47 10.7 0.1 0.47 10.7 0.1 3.6 4 0 0 4 4 3 0 AAA domain rve PF00665.26 CDJ50822.1 - 0.00028 21.0 0.0 0.00059 20.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain EF-hand_1 PF00036.32 CDJ50823.1 - 1.4e-23 80.6 1.0 3e-07 29.5 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 CDJ50823.1 - 4.8e-22 76.4 7.7 1.5e-07 30.6 0.0 5.0 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 CDJ50823.1 - 1.4e-18 65.1 0.8 1.9e-05 24.2 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 CDJ50823.1 - 7.3e-17 61.6 0.1 3.8e-09 36.9 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair Pkinase PF00069.25 CDJ50823.1 - 1.5e-15 57.3 0.0 2.2e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_8 PF13833.6 CDJ50823.1 - 1.6e-10 40.6 0.9 0.027 14.3 0.0 3.9 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ50823.1 - 6.1e-06 26.5 0.1 0.0026 18.1 0.0 2.8 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_Tyr PF07714.17 CDJ50823.1 - 9.7e-05 21.8 0.1 0.00021 20.6 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_4 PF12763.7 CDJ50823.1 - 0.00099 19.0 0.2 0.02 14.8 0.0 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Med24_N PF11277.8 CDJ50823.1 - 0.039 12.0 0.9 0.081 11.0 0.1 1.6 1 1 0 2 2 2 0 Mediator complex subunit 24 N-terminal Excalibur PF05901.11 CDJ50823.1 - 0.057 14.1 0.5 26 5.5 0.0 3.0 3 0 0 3 3 3 0 Excalibur calcium-binding domain EF-hand_10 PF14788.6 CDJ50823.1 - 0.12 12.3 0.0 3.9 7.4 0.0 2.7 2 0 0 2 2 2 0 EF hand Kinase-like PF14531.6 CDJ50823.1 - 0.12 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SRP-alpha_N PF04086.13 CDJ50825.1 - 0.00073 19.6 3.6 0.00092 19.2 3.6 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal IMUP PF15761.5 CDJ50825.1 - 0.019 15.7 5.6 0.035 14.8 5.6 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF1635 PF07795.11 CDJ50825.1 - 0.03 14.2 1.0 0.056 13.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Apt1 PF10351.9 CDJ50825.1 - 0.041 12.7 1.5 0.042 12.7 1.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ50825.1 - 0.41 9.4 4.8 0.53 9.0 4.8 1.1 1 0 0 1 1 1 0 Presenilin Dehydrin PF00257.19 CDJ50825.1 - 0.41 11.2 9.8 0.062 13.9 4.7 1.9 2 0 0 2 2 2 0 Dehydrin Menin PF05053.13 CDJ50825.1 - 2 6.7 5.8 2.5 6.3 5.8 1.1 1 0 0 1 1 1 0 Menin SR-25 PF10500.9 CDJ50827.1 - 0.0002 21.0 11.3 0.0002 21.0 11.3 17.4 5 1 3 8 8 8 3 Nuclear RNA-splicing-associated protein WPP PF13943.6 CDJ50827.1 - 0.04 14.3 0.4 0.04 14.3 0.4 3.0 2 0 0 2 2 2 0 WPP domain Phage_holin_6_1 PF09682.10 CDJ50828.1 - 0.33 11.4 4.7 4.9 7.6 1.6 3.2 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3958 PF13125.6 CDJ50828.1 - 3.2 8.0 8.9 17 5.7 3.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) FAM199X PF15814.5 CDJ50830.1 - 0.00094 18.3 14.5 0.0011 18.1 14.5 1.0 1 0 0 1 1 1 1 Protein family FAM199X RXLR PF16810.5 CDJ50830.1 - 0.19 12.1 10.6 0.26 11.7 10.6 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity XAP5 PF04921.14 CDJ50830.1 - 0.96 9.2 6.9 1.1 9.1 6.9 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator EIF4E-T PF10477.9 CDJ50830.1 - 1.3 7.8 8.8 1.4 7.7 8.8 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF726 PF05277.12 CDJ50830.1 - 2.2 7.1 8.0 2.4 7.0 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF2232 PF09991.9 CDJ50830.1 - 2.8 7.0 4.9 3.3 6.8 4.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Dehydrin PF00257.19 CDJ50830.1 - 6.4 7.3 12.5 7.8 7.0 12.5 1.1 1 0 0 1 1 1 0 Dehydrin R_equi_Vir PF05526.11 CDJ50830.1 - 9.2 6.1 13.7 11 5.8 13.7 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RabGAP-TBC PF00566.18 CDJ50831.1 - 3.9e-32 111.7 0.8 1.1e-16 61.2 0.1 3.1 2 1 0 2 2 2 2 Rab-GTPase-TBC domain SPX PF03105.19 CDJ50831.1 - 0.61 9.9 7.7 0.076 12.9 2.9 1.8 2 0 0 2 2 2 0 SPX domain Peptidase_C48 PF02902.19 CDJ50832.1 - 1.2e-06 28.5 0.0 2.2e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Activator_LAG-3 PF11498.8 CDJ50834.1 - 0.0081 15.2 26.6 0.0098 14.9 26.6 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ50834.1 - 0.012 15.6 11.4 0.012 15.6 11.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 CDJ50834.1 - 0.048 13.7 2.9 0.047 13.7 2.9 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ50834.1 - 0.14 11.7 16.5 0.16 11.6 16.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF2478 PF10649.9 CDJ50834.1 - 0.96 9.0 10.6 4 7.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2478) DUF2722 PF10846.8 CDJ50834.1 - 4.9 6.0 16.7 6.2 5.6 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SpoIIP PF07454.11 CDJ50836.1 - 0.1 12.0 15.3 0.1 12.1 15.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Paf1 PF03985.13 CDJ50836.1 - 0.18 10.8 18.1 0.15 11.0 18.1 1.2 1 0 0 1 1 1 0 Paf1 SID-1_RNA_chan PF13965.6 CDJ50836.1 - 0.23 9.8 4.5 0.22 9.9 4.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 CDJ50836.1 - 0.23 9.7 12.0 0.22 9.8 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 CDJ50836.1 - 0.26 11.0 10.6 0.24 11.1 10.6 1.1 1 0 0 1 1 1 0 Connexin NPR3 PF03666.13 CDJ50836.1 - 0.45 9.3 12.2 0.38 9.5 12.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Band_3_cyto PF07565.13 CDJ50836.1 - 0.81 9.4 13.6 0.74 9.6 13.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MDM10 PF12519.8 CDJ50836.1 - 1.2 7.9 11.4 1.1 8.1 11.4 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 V_ATPase_I PF01496.19 CDJ50836.1 - 1.3 6.8 15.8 1.1 7.0 15.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF-3_zeta PF05091.12 CDJ50836.1 - 2 7.3 25.9 2 7.3 25.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1980 PF09323.10 CDJ50836.1 - 3.5 7.5 14.2 3.8 7.4 14.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) FAM60A PF15396.6 CDJ50836.1 - 3.6 7.5 14.2 3.9 7.4 14.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.17 CDJ50836.1 - 3.8 7.6 20.0 4.8 7.3 20.0 1.2 1 0 0 1 1 1 0 DDHD domain ALMT PF11744.8 CDJ50836.1 - 3.8 6.2 11.6 3.4 6.4 11.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 CDJ50836.1 - 4 7.4 14.0 4.6 7.2 14.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DcuA_DcuB PF03605.14 CDJ50836.1 - 4.1 6.2 12.0 6.3 5.6 12.0 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Rrn6 PF10214.9 CDJ50836.1 - 4.4 5.7 20.6 3.7 5.9 20.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SLC12 PF03522.15 CDJ50836.1 - 4.7 6.1 17.5 4.6 6.2 17.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FAM199X PF15814.5 CDJ50836.1 - 6.3 5.8 19.7 7.7 5.5 19.7 1.1 1 0 0 1 1 1 0 Protein family FAM199X Serinc PF03348.15 CDJ50836.1 - 8.3 5.2 12.8 8.8 5.1 12.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF913 PF06025.12 CDJ50836.1 - 10 5.0 14.0 10 5.0 14.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 CDJ50837.1 - 1.1 9.5 6.2 0.35 11.2 3.2 1.6 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MAT1 PF06391.13 CDJ50837.1 - 1.6 8.5 8.5 0.32 10.8 4.5 1.7 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 RskA PF10099.9 CDJ50838.1 - 0.0073 16.6 17.7 0.0073 16.6 17.7 3.7 2 1 1 3 3 3 2 Anti-sigma-K factor rskA Beach PF02138.18 CDJ50840.1 - 3.7e-48 164.3 0.0 2.9e-28 99.0 0.0 2.4 2 0 0 2 2 2 2 Beige/BEACH domain WD40 PF00400.32 CDJ50840.1 - 2.5e-05 24.9 0.1 0.00066 20.4 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat SPX PF03105.19 CDJ50840.1 - 0.27 11.1 26.9 0.99 9.2 15.4 2.4 2 1 0 2 2 2 0 SPX domain ASD2 PF08687.11 CDJ50840.1 - 2.5 7.6 9.2 0.57 9.7 5.3 1.8 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Surface_antigen PF11054.8 CDJ50841.1 - 2.6e-31 109.2 12.3 4.3e-24 85.5 8.5 2.9 2 1 0 2 2 2 2 Sporozoite TA4 surface antigen Form-deh_trans PF09163.11 CDJ50841.1 - 0.12 12.1 2.5 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane DUF4148 PF13663.6 CDJ50841.1 - 0.15 12.2 0.3 0.15 12.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF3439 PF11921.8 CDJ50841.1 - 5.6 7.0 10.3 12 5.9 10.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Surface_antigen PF11054.8 CDJ50842.1 - 1.8e-25 90.0 15.7 1.5e-19 70.6 10.9 3.0 2 1 0 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ50843.1 - 9.4e-30 104.1 11.8 2.2e-23 83.2 8.3 2.9 2 1 0 2 2 2 2 Sporozoite TA4 surface antigen DUF3439 PF11921.8 CDJ50843.1 - 0.16 11.9 9.8 0.46 10.5 9.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF908 PF06012.12 CDJ50843.1 - 0.22 10.9 2.6 0.22 10.9 2.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Form-deh_trans PF09163.11 CDJ50843.1 - 0.5 10.2 2.6 3.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane DUF1180 PF06679.12 CDJ50843.1 - 7.7 6.9 9.8 9.4 6.6 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Surface_antigen PF11054.8 CDJ50844.1 - 6.2e-56 189.8 16.9 1.1e-26 94.0 4.6 4.1 4 0 0 4 4 4 4 Sporozoite TA4 surface antigen DUF908 PF06012.12 CDJ50844.1 - 5.3 6.4 15.7 3.6 6.9 5.3 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Surface_antigen PF11054.8 CDJ50845.1 - 1.9e-21 76.8 7.1 7.6e-16 58.5 1.5 3.0 3 0 0 3 3 3 3 Sporozoite TA4 surface antigen DUF3439 PF11921.8 CDJ50845.1 - 0.68 9.9 9.1 1.3 9.0 7.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Surface_antigen PF11054.8 CDJ50846.1 - 5.6e-19 68.8 10.1 1.1e-17 64.6 10.1 2.0 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ50847.1 - 7.7e-24 84.7 12.8 4.3e-22 79.0 11.5 2.9 2 1 0 2 2 2 1 Sporozoite TA4 surface antigen DUF3439 PF11921.8 CDJ50847.1 - 3.3 7.7 11.6 7.8 6.5 11.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Surface_antigen PF11054.8 CDJ50848.1 - 1.1e-24 87.4 6.0 1e-22 81.0 5.1 2.9 2 1 0 2 2 2 2 Sporozoite TA4 surface antigen Pal1 PF08316.11 CDJ50849.1 - 0.3 11.8 10.2 0.5 11.1 10.2 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF4569 PF15133.6 CDJ50849.1 - 1.3 8.6 24.6 1.5 8.5 24.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DREPP PF05558.12 CDJ50849.1 - 1.7 8.5 9.6 2.1 8.2 9.6 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide AUX_IAA PF02309.16 CDJ50849.1 - 2 8.2 16.8 2.1 8.2 16.8 1.0 1 0 0 1 1 1 0 AUX/IAA family DUF2126 PF09899.9 CDJ50849.1 - 2.7 5.9 15.0 3.6 5.5 15.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Zip PF02535.22 CDJ50849.1 - 3.4 6.8 12.5 3.4 6.8 12.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 CDJ50849.1 - 5.2 6.8 30.0 6.4 6.5 30.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 CDJ50849.1 - 7.5 5.3 22.5 8.3 5.2 22.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NPR3 PF03666.13 CDJ50849.1 - 7.8 5.2 18.9 8.6 5.0 18.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MRP-S26 PF14943.6 CDJ50849.1 - 8.6 6.2 29.4 11 5.9 29.4 1.0 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF2722 PF10846.8 CDJ50850.1 - 0.004 16.2 18.5 0.0042 16.1 13.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ50850.1 - 0.016 15.5 53.9 0.02 15.2 31.6 4.1 3 1 1 4 4 4 0 Anti-sigma-K factor rskA SARAF PF06682.12 CDJ50850.1 - 0.19 11.3 13.1 0.024 14.3 1.6 2.7 2 1 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis BAF1_ABF1 PF04684.13 CDJ50850.1 - 0.78 8.7 5.7 1.3 8.0 5.7 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ50850.1 - 0.83 8.4 7.2 1.4 7.6 7.2 1.3 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ50850.1 - 1.1 7.9 9.5 1.5 7.4 9.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 CDJ50850.1 - 1.7 8.2 37.5 7.5 6.1 0.4 2.2 2 0 0 2 2 2 0 Spt20 family eIF-3_zeta PF05091.12 CDJ50850.1 - 5.8 5.8 12.0 0.16 10.9 5.6 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ50850.1 - 9.3 6.2 11.8 0.82 9.7 6.2 1.9 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Mic1 PF07035.12 CDJ50852.1 - 0.17 11.6 0.9 2.4 7.9 0.3 2.3 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like DUF2722 PF10846.8 CDJ50852.1 - 0.77 8.6 6.8 1.5 7.7 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Roughex PF06020.11 CDJ50852.1 - 1.6 7.7 6.1 3.1 6.8 6.1 1.4 1 0 0 1 1 1 0 Drosophila roughex protein CCDC53 PF10152.9 CDJ50852.1 - 1.9 8.9 8.6 0.82 10.1 1.8 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 CDJ50852.1 - 2.3 7.8 14.2 0.5 9.9 10.5 1.6 2 0 0 2 2 2 0 Spt20 family Dehydrin PF00257.19 CDJ50852.1 - 2.8 8.5 21.0 10 6.6 0.7 3.3 3 0 0 3 3 3 0 Dehydrin DUF92 PF01940.16 CDJ50853.1 - 0.075 12.4 5.1 0.086 12.2 5.1 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF92 DUF4647 PF15504.6 CDJ50853.1 - 0.094 11.8 5.6 0.097 11.8 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Spt20 PF12090.8 CDJ50853.1 - 0.096 12.3 23.8 0.11 12.1 23.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ50853.1 - 0.11 11.5 17.3 0.11 11.4 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NACHT_N PF17100.5 CDJ50853.1 - 0.62 9.9 9.8 0.68 9.8 9.8 1.1 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase DUF4834 PF16118.5 CDJ50853.1 - 0.82 10.7 6.7 1 10.3 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Methyltransf_34 PF11312.8 CDJ50853.1 - 0.9 8.7 8.3 1.1 8.4 8.3 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Pex14_N PF04695.13 CDJ50853.1 - 1.1 9.9 16.0 1.3 9.6 16.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RIFIN PF02009.16 CDJ50853.1 - 1.2 8.9 10.7 1.5 8.7 10.7 1.1 1 0 0 1 1 1 0 Rifin TFIIA PF03153.13 CDJ50853.1 - 2.1 8.3 28.6 2 8.3 28.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 CDJ50853.1 - 2.5 8.1 11.1 2.6 8.1 11.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Med15 PF09606.10 CDJ50853.1 - 2.6 6.6 26.4 3 6.4 26.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.16 CDJ50853.1 - 2.6 8.0 6.8 2.6 8.1 6.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ50853.1 - 4 7.2 7.9 4 7.2 7.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.17 CDJ50853.1 - 7.2 6.7 8.4 7.1 6.7 8.4 1.1 1 0 0 1 1 1 0 DDHD domain AUX_IAA PF02309.16 CDJ50853.1 - 8.1 6.2 7.8 8.5 6.2 7.8 1.1 1 0 0 1 1 1 0 AUX/IAA family eIF-3_zeta PF05091.12 CDJ50854.1 - 0.0026 16.8 4.0 0.0026 16.8 4.0 5.0 3 2 1 5 5 5 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RskA PF10099.9 CDJ50855.1 - 0.00017 21.9 10.1 0.00017 21.9 10.1 4.1 3 1 0 3 3 3 2 Anti-sigma-K factor rskA DUF1645 PF07816.11 CDJ50855.1 - 0.00067 20.3 18.0 0.00067 20.3 18.0 4.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1645) FAM199X PF15814.5 CDJ50855.1 - 0.01 14.9 0.9 0.01 14.9 0.9 4.5 3 2 1 4 4 4 0 Protein family FAM199X SR-25 PF10500.9 CDJ50855.1 - 0.11 12.1 0.1 0.11 12.1 0.1 5.4 3 2 2 5 5 5 0 Nuclear RNA-splicing-associated protein ESM4 PF15952.5 CDJ50855.1 - 0.16 12.3 50.8 0.2 12.1 24.6 3.4 3 0 0 3 3 3 0 Enhancer of split M4 family Ecl1 PF12855.7 CDJ50855.1 - 2 9.5 73.8 0.18 12.9 17.2 3.1 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins MCU PF04678.13 CDJ50855.1 - 4.1 7.5 24.0 2.1 8.4 1.2 3.3 3 0 0 3 3 3 0 Mitochondrial calcium uniporter Hexapep PF00132.24 CDJ50856.1 - 4.3e-09 35.7 2.0 0.0004 20.0 1.1 3.8 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DUF2722 PF10846.8 CDJ50856.1 - 5e-06 25.7 16.7 0.0044 16.0 1.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) DUF4954 PF16314.5 CDJ50856.1 - 1.2e-05 23.8 0.2 1.8e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) CCDC53 PF10152.9 CDJ50856.1 - 0.00099 19.6 10.9 0.23 11.9 0.4 3.3 3 0 0 3 3 3 2 Subunit CCDC53 of WASH complex TFIIA PF03153.13 CDJ50856.1 - 0.0018 18.4 30.5 0.0067 16.5 11.6 2.5 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 CDJ50856.1 - 0.0056 17.1 6.6 0.055 13.8 1.5 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like Hexapep_2 PF14602.6 CDJ50856.1 - 0.013 15.2 10.5 0.013 15.2 1.2 2.9 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase HNOBA PF07701.14 CDJ50856.1 - 0.014 14.8 0.3 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Heme NO binding associated Spt20 PF12090.8 CDJ50856.1 - 0.017 14.8 39.1 0.078 12.6 9.3 2.2 2 0 0 2 2 2 0 Spt20 family CPSF100_C PF13299.6 CDJ50856.1 - 0.023 14.9 8.2 0.38 10.9 2.6 3.1 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DUF2052 PF09747.9 CDJ50856.1 - 0.14 12.2 9.8 0.38 10.9 5.9 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Band_3_cyto PF07565.13 CDJ50856.1 - 0.24 11.1 4.8 0.78 9.5 0.4 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain UPF0560 PF10577.9 CDJ50856.1 - 0.26 9.7 18.2 0.082 11.4 7.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 DUF719 PF05334.13 CDJ50856.1 - 0.41 10.8 6.1 3 8.0 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF3408 PF11888.8 CDJ50856.1 - 0.42 10.7 11.2 0.8 9.8 4.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Gti1_Pac2 PF09729.9 CDJ50856.1 - 0.45 10.6 4.4 1.7 8.7 0.8 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family Neur_chan_memb PF02932.16 CDJ50856.1 - 0.52 10.3 5.8 0.77 9.8 0.5 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.10 CDJ50856.1 - 0.99 8.0 38.0 0.035 12.8 6.6 2.4 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal SpoIIP PF07454.11 CDJ50856.1 - 1.1 8.6 9.8 0.3 10.5 2.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) PAT1 PF09770.9 CDJ50856.1 - 2.1 6.5 18.8 2.4 6.3 9.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ50856.1 - 2.2 7.4 3.9 4.6 6.4 2.5 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Afi1 PF07792.12 CDJ50856.1 - 2.8 8.4 10.1 6.7 7.2 5.0 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ndc1_Nup PF09531.10 CDJ50856.1 - 3.3 6.3 9.8 1.4 7.5 1.6 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Tim54 PF11711.8 CDJ50856.1 - 4.6 5.9 7.9 5.4 5.7 3.9 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4820 PF16091.5 CDJ50856.1 - 4.9 6.5 8.6 6.2 6.1 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) eIF-3_zeta PF05091.12 CDJ50856.1 - 7.1 5.5 14.6 8.7 5.2 7.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RPA43_OB PF17875.1 CDJ50856.1 - 7.7 7.2 8.1 35 5.0 4.7 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF702 PF05142.12 CDJ50856.1 - 8.5 6.8 14.2 16 6.0 6.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Pex14_N PF04695.13 CDJ50857.1 - 0.95 10.1 14.0 1.3 9.7 14.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.13 CDJ50857.1 - 2.4 7.1 11.4 3.2 6.7 11.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Lin-8 PF03353.15 CDJ50857.1 - 4.2 6.8 8.0 4.8 6.7 8.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CPSF100_C PF13299.6 CDJ50857.1 - 6.1 7.0 7.7 8.3 6.6 7.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 CDJ50857.1 - 9.7 6.1 17.2 11 5.9 17.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTP1_OBG PF01018.22 CDJ50858.1 - 7.9e-23 80.8 5.3 1.3e-21 76.8 5.3 2.4 1 1 0 1 1 1 1 GTP1/OBG GTP_EFTU PF00009.27 CDJ50858.1 - 4.4e-07 29.6 0.1 0.00015 21.3 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ50858.1 - 7.6e-06 26.0 0.1 2e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CDJ50858.1 - 0.0013 18.2 0.0 0.0047 16.4 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 CDJ50858.1 - 0.0079 16.0 0.0 0.074 12.8 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CDJ50858.1 - 0.014 15.1 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1967 PF09269.11 CDJ50858.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) SRPRB PF09439.10 CDJ50858.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 CDJ50858.1 - 0.54 10.7 4.8 1.4 9.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain IMS PF00817.20 CDJ50860.1 - 2.1e-39 134.9 0.2 6e-39 133.4 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 CDJ50860.1 - 2.3e-13 50.8 0.4 7.4e-13 49.2 0.4 1.9 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CDJ50860.1 - 0.00083 19.5 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.8 CDJ50860.1 - 0.016 15.4 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 Pathogenicity locus TfoX_C PF04994.13 CDJ50860.1 - 0.067 13.3 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 TfoX C-terminal domain Caps_synth_GfcC PF06251.11 CDJ50860.1 - 0.23 11.1 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Capsule biosynthesis GfcC Uso1_p115_C PF04871.13 CDJ50860.1 - 0.4 11.1 6.5 6.3 7.2 0.1 3.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Folate_rec PF03024.14 CDJ50861.1 - 6.1e-11 42.5 6.3 8.3e-11 42.0 6.3 1.2 1 0 0 1 1 1 1 Folate receptor family MORN PF02493.20 CDJ50862.1 - 9.5e-12 44.1 10.0 0.00046 19.9 0.0 5.5 5 0 0 5 5 5 4 MORN repeat AP2 PF00847.20 CDJ50862.1 - 0.16 12.2 0.2 0.33 11.2 0.2 1.4 1 0 0 1 1 1 0 AP2 domain DUF2561 PF10812.8 CDJ50863.1 - 0.44 10.5 3.0 0.7 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) BTK PF00779.19 CDJ50864.1 - 0.086 12.7 0.7 0.19 11.6 0.7 1.5 1 0 0 1 1 1 0 BTK motif DUF3827 PF12877.7 CDJ50864.1 - 1.1 7.5 8.6 1.8 6.8 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TMEM220 PF15071.6 CDJ50865.1 - 0.5 11.2 8.6 3 8.7 8.6 2.4 1 1 0 1 1 1 0 Transmembrane family 220, helix NDK PF00334.19 CDJ50866.1 - 1.3e-20 73.8 0.0 5.3e-14 52.4 0.0 3.7 3 0 0 3 3 3 2 Nucleoside diphosphate kinase AAA_17 PF13207.6 CDJ50866.1 - 0.025 15.0 0.0 5.2 7.5 0.0 4.0 4 0 0 4 4 4 0 AAA domain Draxin PF15550.6 CDJ50866.1 - 3.9 7.2 8.8 2.8 7.7 5.5 2.2 2 0 0 2 2 2 0 Draxin Activator_LAG-3 PF11498.8 CDJ50867.1 - 4.4 6.2 10.3 5.5 5.8 10.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RRM_1 PF00076.22 CDJ50868.1 - 2.2e-15 56.2 0.0 4.9e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 CDJ50868.1 - 6.7e-15 54.8 0.1 1.3e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Surp module cwf21 PF08312.12 CDJ50868.1 - 6.4e-13 48.6 6.4 6.4e-13 48.6 6.4 2.4 2 0 0 2 2 2 1 cwf21 domain CTK3 PF12243.8 CDJ50868.1 - 0.00017 21.6 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Ku_C PF03730.14 CDJ50868.1 - 1.7 9.4 11.2 0.55 11.0 6.3 2.8 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm Tubulin PF00091.25 CDJ50869.1 - 3.9e-33 115.3 0.0 9.9e-26 91.2 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 CDJ50869.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Tubulin like E1-E2_ATPase PF00122.20 CDJ50870.1 - 3e-40 137.7 0.1 7.9e-40 136.3 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ50870.1 - 3.7e-20 73.1 0.1 7.9e-20 72.0 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDJ50870.1 - 2e-11 43.4 0.0 4.7e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CDJ50870.1 - 1.8e-05 24.8 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDJ50870.1 - 0.0026 17.5 0.1 0.0051 16.6 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TM231 PF10149.9 CDJ50871.1 - 0.2 10.9 0.1 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 231 EF-hand_7 PF13499.6 CDJ50872.1 - 2.1e-25 89.0 0.0 1e-10 41.9 0.0 4.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ50872.1 - 2.8e-19 67.3 0.3 0.00011 21.8 0.0 6.3 5 1 1 6 6 6 5 EF-hand domain EF-hand_1 PF00036.32 CDJ50872.1 - 1.9e-18 64.5 0.0 1.6e-05 24.1 0.0 6.1 5 1 1 6 6 6 4 EF hand EF-hand_8 PF13833.6 CDJ50872.1 - 1.6e-15 56.7 0.3 4.8e-06 26.3 0.0 4.6 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 CDJ50872.1 - 5.7e-12 44.5 0.0 5.2e-05 22.6 0.0 4.3 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 CDJ50872.1 - 7e-05 23.1 0.0 0.00092 19.5 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CDJ50872.1 - 0.065 13.4 0.3 23 5.3 0.0 3.3 3 0 0 3 3 3 0 Dockerin type I domain HAP2-GCS1 PF10699.9 CDJ50873.1 - 4.4e-09 36.2 0.1 1.2e-08 34.8 0.1 1.8 1 0 0 1 1 1 1 Male gamete fusion factor SAS4 PF15460.6 CDJ50873.1 - 0.53 10.4 3.8 1.4 9.1 3.8 1.7 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Guanylate_cyc PF00211.20 CDJ50874.1 - 2.3e-17 63.2 0.2 4.9e-17 62.1 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.31 CDJ50874.1 - 2.1e-06 27.1 5.0 2.1e-06 27.1 5.0 1.9 2 0 0 2 2 2 1 Ion transport protein DUF2052 PF09747.9 CDJ50875.1 - 0.011 15.9 2.0 0.011 15.9 2.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TYW3 PF02676.14 CDJ50875.1 - 0.018 14.4 0.2 0.04 13.3 0.2 1.5 1 0 0 1 1 1 0 Methyltransferase TYW3 V_ATPase_I PF01496.19 CDJ50875.1 - 0.027 12.4 13.8 0.042 11.8 13.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ50875.1 - 0.13 12.0 4.6 0.22 11.2 4.6 1.3 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 CDJ50875.1 - 0.21 10.0 0.7 0.28 9.5 0.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF-3_zeta PF05091.12 CDJ50875.1 - 0.51 9.3 7.8 0.72 8.8 7.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ50875.1 - 0.77 8.5 14.7 0.042 12.6 5.7 2.0 2 0 0 2 2 2 0 Presenilin Band_3_cyto PF07565.13 CDJ50875.1 - 1.8 8.3 8.8 0.23 11.2 4.8 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FAM60A PF15396.6 CDJ50875.1 - 4.2 7.3 10.1 1.1e+02 2.7 0.0 2.4 2 0 0 2 2 2 0 Protein Family FAM60A SpoIIP PF07454.11 CDJ50875.1 - 5.9 6.3 11.4 0.43 10.0 6.6 1.5 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) YABBY PF04690.13 CDJ50875.1 - 8.4 6.9 9.9 1.2 9.7 5.2 1.9 2 0 0 2 2 2 0 YABBY protein MMR1 PF08505.10 CDJ50875.1 - 8.5 6.6 14.9 2.1e+02 2.0 0.0 2.3 2 1 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein SUIM_assoc PF16619.5 CDJ50876.1 - 4e-09 36.4 28.6 1.1e+03 -0.3 28.6 4.9 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PAT1 PF09770.9 CDJ50876.1 - 0.0002 19.8 25.1 0.00021 19.8 25.1 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ50876.1 - 0.0016 17.3 22.3 0.002 17.0 22.3 1.1 1 0 0 1 1 1 1 Presenilin RR_TM4-6 PF06459.12 CDJ50876.1 - 0.0069 16.3 20.9 0.0099 15.7 20.9 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 SAGA-Tad1 PF12767.7 CDJ50876.1 - 0.041 13.6 17.3 0.05 13.3 17.3 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Asp-B-Hydro_N PF05279.11 CDJ50876.1 - 0.14 12.2 12.9 0.18 11.8 12.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SID-1_RNA_chan PF13965.6 CDJ50876.1 - 0.38 9.1 3.4 0.47 8.8 3.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF913 PF06025.12 CDJ50876.1 - 0.41 9.6 9.7 0.64 8.9 9.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Raftlin PF15250.6 CDJ50876.1 - 0.42 9.3 16.0 0.62 8.8 16.0 1.2 1 0 0 1 1 1 0 Raftlin Endostatin PF06482.11 CDJ50876.1 - 0.52 9.7 16.4 0.7 9.3 16.4 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SLC12 PF03522.15 CDJ50876.1 - 0.55 9.2 22.6 0.74 8.8 22.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 CDJ50876.1 - 0.62 10.1 15.7 0.95 9.5 15.7 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Lin-8 PF03353.15 CDJ50876.1 - 1.2 8.7 24.9 1.6 8.2 24.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 CDJ50876.1 - 1.8 5.6 20.0 2.2 5.3 20.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CLN3 PF02487.17 CDJ50876.1 - 3.9 6.4 14.1 7 5.6 14.1 1.5 1 0 0 1 1 1 0 CLN3 protein Hid1 PF12722.7 CDJ50876.1 - 4.2 5.4 22.3 4.9 5.2 22.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PA26 PF04636.13 CDJ50876.1 - 4.3 6.1 13.6 5.3 5.9 13.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MMR1 PF08505.10 CDJ50876.1 - 6 7.1 25.6 11 6.3 25.6 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Zip PF02535.22 CDJ50876.1 - 6.8 5.8 13.1 9.1 5.4 13.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cellulose_synt PF03552.14 CDJ50876.1 - 7 5.0 7.3 8.8 4.7 7.3 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF2052 PF09747.9 CDJ50876.1 - 8 6.5 30.8 8.6 6.4 29.1 1.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Med15 PF09606.10 CDJ50876.1 - 9.4 4.8 45.5 14 4.2 45.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S8 PF00082.22 CDJ50877.1 - 8.9e-05 21.9 0.9 8.9e-05 21.9 0.9 3.0 3 0 0 3 3 3 1 Subtilase family SR-25 PF10500.9 CDJ50877.1 - 0.0099 15.5 14.6 0.0099 15.5 14.6 3.3 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ50877.1 - 0.083 13.2 74.5 0.064 13.5 3.5 5.5 3 1 1 4 4 4 0 Anti-sigma-K factor rskA DUF4342 PF14242.6 CDJ50877.1 - 0.13 12.2 0.0 0.58 10.2 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) DUF4045 PF13254.6 CDJ50877.1 - 3.1 7.3 35.6 2.5 7.6 18.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) SR-25 PF10500.9 CDJ50879.1 - 0.08 12.5 9.2 0.091 12.4 9.2 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MARVEL PF01284.23 CDJ50879.1 - 6.9 6.7 11.1 10 6.2 11.1 1.3 1 0 0 1 1 1 0 Membrane-associating domain zf-RING_2 PF13639.6 CDJ50880.1 - 1.6e-11 44.3 10.8 1.6e-11 44.3 10.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CDJ50880.1 - 8.5e-08 32.4 7.2 8.5e-08 32.4 7.2 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CDJ50880.1 - 4.1e-06 26.5 8.4 4.1e-06 26.5 8.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 CDJ50880.1 - 5.3e-06 26.4 5.0 1.2e-05 25.3 5.0 1.6 1 0 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 CDJ50880.1 - 6.8e-06 26.1 4.1 6.8e-06 26.1 4.1 1.5 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CDJ50880.1 - 1.3e-05 24.8 2.2 1.3e-05 24.8 2.2 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDJ50880.1 - 2.4e-05 24.1 10.4 2.4e-05 24.1 10.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ50880.1 - 3.6e-05 23.6 6.7 3.6e-05 23.6 6.7 2.0 2 1 1 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDJ50880.1 - 0.00011 22.1 0.9 0.00011 22.1 0.9 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ50880.1 - 0.00028 20.7 6.4 0.00028 20.7 6.4 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CDJ50880.1 - 0.00052 19.8 5.0 0.00096 18.9 5.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF5318 PF17249.2 CDJ50880.1 - 0.00081 19.2 1.2 0.0015 18.3 1.2 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5318) zf-P11 PF03854.14 CDJ50880.1 - 0.01 15.5 0.8 0.01 15.5 0.8 2.6 2 1 1 3 3 3 1 P-11 zinc finger Prok-RING_4 PF14447.6 CDJ50880.1 - 0.02 14.7 7.4 0.02 14.7 7.4 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 CDJ50880.1 - 0.062 13.2 8.6 0.15 12.0 2.8 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 CDJ50880.1 - 0.4 10.9 11.8 0.062 13.5 6.2 2.3 2 1 0 2 2 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CDJ50880.1 - 0.55 9.9 12.0 0.064 12.9 6.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Spt20 PF12090.8 CDJ50881.1 - 0.013 15.2 50.1 0.05 13.2 6.4 3.4 3 1 0 3 3 3 0 Spt20 family Med1 PF10744.9 CDJ50881.1 - 0.048 12.7 0.1 0.048 12.7 0.1 3.1 3 1 0 3 3 3 0 Mediator of RNA polymerase II transcription subunit 1 WBP-1 PF11669.8 CDJ50881.1 - 0.17 12.5 11.7 5.9 7.6 0.5 3.7 3 0 0 3 3 3 0 WW domain-binding protein 1 DUF4770 PF15994.5 CDJ50881.1 - 3.8 7.7 18.1 3.6 7.8 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) ArsC PF03960.15 CDJ50884.1 - 3.8 7.6 6.7 8.1 6.5 2.2 3.2 2 1 0 3 3 3 0 ArsC family rve PF00665.26 CDJ50886.1 - 2.1e-10 40.8 0.0 3.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ50886.1 - 0.00029 20.7 0.9 0.00047 20.0 0.1 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 CDJ50887.1 - 6.5e-16 58.2 2.4 1.3e-15 57.2 2.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CDJ50887.1 - 2.6e-11 43.4 0.0 6.3e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 CDJ50887.1 - 3.4e-07 30.8 0.0 7.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ50887.1 - 3.7e-06 27.4 0.0 7.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 CDJ50887.1 - 0.00012 22.3 0.0 0.00036 20.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 CDJ50887.1 - 0.00014 21.7 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 CDJ50887.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 CDJ50887.1 - 0.0016 18.6 0.6 0.0036 17.5 0.6 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RVP PF00077.20 CDJ50887.1 - 0.029 14.7 0.0 0.084 13.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ50887.1 - 0.18 11.6 0.0 0.46 10.3 0.0 1.6 2 0 0 2 2 2 0 Aspartyl protease RVT_1 PF00078.27 CDJ50888.1 - 1.4e-06 28.0 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CDJ50889.1 - 1.9e-06 27.7 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ50889.1 - 1.1e-05 26.0 0.0 2.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ50889.1 - 1.1e-05 25.9 0.0 2.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease NinF PF05810.12 CDJ50889.1 - 0.053 13.4 0.6 1.7 8.5 0.1 2.4 2 0 0 2 2 2 0 NinF protein DUF4599 PF15371.6 CDJ50889.1 - 0.6 10.7 3.1 0.37 11.4 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) RIG-I_C PF18119.1 CDJ50890.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain DUF2722 PF10846.8 CDJ50892.1 - 0.00053 19.1 4.1 0.00053 19.1 4.1 7.2 4 3 2 6 6 6 1 Protein of unknown function (DUF2722) Sin_N PF04801.13 CDJ50892.1 - 0.0028 16.9 16.8 0.0028 16.9 16.8 4.7 4 1 1 5 5 5 1 Sin-like protein conserved region TFIIA PF03153.13 CDJ50892.1 - 0.0053 16.8 6.7 0.0053 16.8 6.7 6.2 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit N-glycanase_C PF09113.10 CDJ50892.1 - 0.088 12.6 0.1 0.27 11.0 0.1 1.8 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal PRIMA1 PF16101.5 CDJ50893.1 - 0.07 13.2 4.7 0.1 12.6 4.7 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 CDJ50893.1 - 0.93 9.5 4.8 1 9.4 4.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator tRNA-synt_1g PF09334.11 CDJ50894.1 - 2.1e-07 30.1 6.7 2.1e-06 26.8 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) SPX PF03105.19 CDJ50894.1 - 0.063 13.2 17.3 0.4 10.5 3.4 2.3 2 0 0 2 2 2 0 SPX domain NFACT-R_1 PF05670.13 CDJ50896.1 - 8e-39 132.7 0.9 5.9e-38 129.9 0.0 3.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain PDEase_I PF00233.19 CDJ50897.1 - 1.1e-56 192.3 0.5 1.1e-56 192.3 0.5 2.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase RskA PF10099.9 CDJ50897.1 - 2.1e-05 24.9 3.5 2.1e-05 24.9 3.5 9.4 4 3 1 6 6 6 1 Anti-sigma-K factor rskA Activator_LAG-3 PF11498.8 CDJ50897.1 - 0.0028 16.7 0.6 0.0028 16.7 0.6 4.5 4 0 0 4 4 4 1 Transcriptional activator LAG-3 Histone PF00125.24 CDJ50898.1 - 6.2e-53 178.6 1.5 6.9e-53 178.5 1.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CDJ50898.1 - 9e-05 22.8 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CDJ50898.1 - 0.00014 22.4 0.9 0.00017 22.2 0.9 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CDJ50898.1 - 0.00038 20.5 0.1 0.00071 19.7 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 CDJ50898.1 - 0.0094 16.0 0.1 0.015 15.3 0.0 1.4 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 CDJ50898.1 - 0.015 15.6 0.1 0.029 14.7 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MetOD2 PF18548.1 CDJ50899.1 - 0.028 14.5 5.9 0.097 12.8 0.1 3.0 2 0 0 2 2 2 0 Metanogen output domain 2 RskA PF10099.9 CDJ50901.1 - 0.0034 17.7 7.8 0.0034 17.7 7.8 4.2 2 1 0 2 2 2 1 Anti-sigma-K factor rskA GT87 PF09594.10 CDJ50901.1 - 0.3 10.8 8.5 0.43 10.2 1.3 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 87 DUF4179 PF13786.6 CDJ50901.1 - 2.1 8.9 13.9 1.3 9.6 0.4 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) MCR_alpha PF02249.17 CDJ50901.1 - 3 8.3 9.3 3.9 8.0 1.5 2.8 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain SR-25 PF10500.9 CDJ50902.1 - 0.0021 17.7 8.1 0.0021 17.7 8.1 6.1 3 1 2 5 5 5 4 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ50903.1 - 0.0027 18.0 2.2 0.0057 17.0 2.2 1.4 1 1 0 1 1 1 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ50903.1 - 0.006 16.6 27.7 0.041 13.9 6.1 2.3 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF2681 PF10883.8 CDJ50903.1 - 0.01 16.2 0.8 0.01 16.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) MITF_TFEB_C_3_N PF15951.5 CDJ50903.1 - 0.019 15.6 1.7 0.019 15.6 1.7 2.1 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus Serinc PF03348.15 CDJ50903.1 - 0.022 13.7 0.8 0.027 13.4 0.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) M_domain PF12938.7 CDJ50903.1 - 0.027 14.3 27.9 0.077 12.8 8.8 2.1 2 0 0 2 2 2 0 M domain of GW182 CDK2AP PF09806.9 CDJ50903.1 - 0.034 14.2 8.7 0.051 13.6 8.7 1.3 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DDDD PF10161.9 CDJ50903.1 - 0.066 13.0 1.3 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Presenilin PF01080.17 CDJ50903.1 - 0.079 11.7 2.0 0.1 11.4 2.0 1.1 1 0 0 1 1 1 0 Presenilin Renin_r PF07850.14 CDJ50903.1 - 0.2 12.3 1.2 5 7.8 1.1 2.0 2 0 0 2 2 2 0 Renin receptor-like protein Med3 PF11593.8 CDJ50903.1 - 0.62 9.2 23.9 0.98 8.5 8.2 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal ANAPC_CDC26 PF10471.9 CDJ50903.1 - 0.82 10.5 24.7 1.8 9.5 6.8 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 TMEM51 PF15345.6 CDJ50903.1 - 0.87 9.4 6.0 2 8.2 0.5 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 RAB3GAP2_N PF14655.6 CDJ50903.1 - 2.2 7.5 9.6 5.2 6.2 0.8 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TPX2 PF06886.11 CDJ50903.1 - 2.7 8.3 17.9 2 8.7 7.7 2.2 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) DUF2434 PF10361.9 CDJ50903.1 - 3.4 6.6 7.6 0.51 9.3 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2434) MAP7 PF05672.11 CDJ50905.1 - 0.019 14.7 47.4 0.024 14.3 47.4 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Rtf2 PF04641.12 CDJ50905.1 - 0.15 11.4 20.7 0.16 11.3 20.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1180 PF06679.12 CDJ50905.1 - 0.27 11.7 10.0 0.31 11.4 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pex14_N PF04695.13 CDJ50905.1 - 0.51 11.0 33.3 0.64 10.7 33.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SRP-alpha_N PF04086.13 CDJ50905.1 - 0.57 10.1 24.2 0.61 10.0 24.2 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4045 PF13254.6 CDJ50905.1 - 0.89 9.1 22.4 0.98 9.0 22.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3807 PF12720.7 CDJ50905.1 - 1.1 9.5 31.0 1.3 9.3 31.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2052 PF09747.9 CDJ50905.1 - 1.2 9.2 29.3 1.4 9.0 29.3 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ50905.1 - 1.3 8.7 25.6 1.5 8.6 25.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.9 CDJ50905.1 - 1.4 8.9 18.1 1.8 8.6 18.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family NPR3 PF03666.13 CDJ50905.1 - 1.5 7.6 19.5 1.6 7.5 19.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PTPRCAP PF15713.5 CDJ50905.1 - 1.5 9.1 24.4 2 8.7 24.4 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 CDJ50905.1 - 1.5 7.0 22.8 1.6 6.9 22.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 CDJ50905.1 - 1.7 6.6 22.2 2.1 6.4 22.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CSG2 PF16965.5 CDJ50905.1 - 1.8 7.5 12.7 2 7.3 12.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4746 PF15928.5 CDJ50905.1 - 1.8 7.9 18.3 2 7.7 18.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 CDJ50905.1 - 1.8 7.3 28.8 1.9 7.1 28.8 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ50905.1 - 2.2 7.1 30.2 2.6 6.9 30.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.6 CDJ50905.1 - 2.4 8.1 17.2 2.7 7.9 17.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.8 CDJ50905.1 - 2.4 6.9 20.4 2.8 6.6 20.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1387 PF07139.11 CDJ50905.1 - 2.4 7.8 25.7 3 7.5 25.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Peptidase_S64 PF08192.11 CDJ50905.1 - 2.9 6.3 19.7 2.8 6.3 19.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 Suf PF05843.14 CDJ50905.1 - 2.9 7.8 29.9 3.1 7.7 29.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.7 CDJ50905.1 - 3.2 5.8 24.1 3.2 5.8 24.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VIR_N PF15912.5 CDJ50905.1 - 3.2 7.3 13.6 3.5 7.2 13.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal NARP1 PF12569.8 CDJ50905.1 - 3.4 6.5 22.4 3.8 6.3 22.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CLN3 PF02487.17 CDJ50905.1 - 3.8 6.5 17.3 4.1 6.3 17.3 1.2 1 0 0 1 1 1 0 CLN3 protein CCDC53 PF10152.9 CDJ50905.1 - 4 7.8 23.8 5.2 7.5 23.8 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex V_ATPase_I PF01496.19 CDJ50905.1 - 4.4 5.1 22.9 4.6 5.0 22.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paf1 PF03985.13 CDJ50905.1 - 4.6 6.1 28.3 5.6 5.9 28.3 1.1 1 0 0 1 1 1 0 Paf1 Membralin PF09746.9 CDJ50905.1 - 4.7 6.1 18.4 5.5 5.9 18.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein Velvet PF11754.8 CDJ50905.1 - 4.7 7.1 23.5 5.5 6.9 23.5 1.1 1 0 0 1 1 1 0 Velvet factor Band_3_cyto PF07565.13 CDJ50905.1 - 6.5 6.5 22.7 7.9 6.2 22.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF913 PF06025.12 CDJ50905.1 - 6.9 5.5 14.7 7.3 5.5 14.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2126 PF09899.9 CDJ50905.1 - 7.6 4.5 16.3 7.9 4.4 16.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CobT PF06213.12 CDJ50905.1 - 8.4 5.7 36.9 10 5.4 36.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Endostatin PF06482.11 CDJ50905.1 - 8.9 5.7 22.5 9.6 5.6 22.5 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF1700 PF08006.11 CDJ50908.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Anoctamin PF04547.12 CDJ50908.1 - 5.9 5.6 5.9 2 7.2 0.1 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel SR-25 PF10500.9 CDJ50909.1 - 0.00038 20.1 21.5 0.00038 20.1 21.5 3.9 4 1 0 4 4 4 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ50909.1 - 0.00082 19.1 11.3 0.00082 19.1 11.3 4.1 3 1 1 4 4 4 1 Spt20 family TFIIA PF03153.13 CDJ50909.1 - 0.0042 17.1 68.2 0.026 14.5 27.8 3.3 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ50910.1 - 0.4 8.9 28.5 0.75 8.0 28.5 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bud13 PF09736.9 CDJ50910.1 - 5.8 7.3 20.8 1.5 9.2 15.9 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Cyclin PF08613.11 CDJ50912.1 - 8.1e-30 104.3 0.0 2.1e-29 102.9 0.0 1.8 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CDJ50912.1 - 6.4e-07 29.2 0.0 6.4e-07 29.2 0.0 3.4 3 1 1 4 4 4 1 Cyclin, N-terminal domain SNF2_N PF00176.23 CDJ50914.1 - 3.1e-14 52.5 0.0 9.5e-12 44.3 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-C4_Topoisom PF01396.19 CDJ50914.1 - 1.7e-09 37.3 3.9 4.6e-09 35.9 3.9 1.7 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Helicase_C PF00271.31 CDJ50914.1 - 0.0086 16.4 0.0 0.075 13.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RNA_polI_A34 PF08208.11 CDJ50915.1 - 4.4 7.3 31.1 7 6.7 31.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Glyco_tran_28_C PF04101.16 CDJ50916.1 - 1.5e-17 64.1 0.0 2.6e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SUIM_assoc PF16619.5 CDJ50916.1 - 0.18 11.9 5.2 2.4 8.3 2.0 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Herpes_TAF50 PF03326.13 CDJ50916.1 - 2.8 6.5 9.8 0.11 11.1 0.4 2.1 2 0 0 2 2 2 0 Herpesvirus transcription activation factor (transactivator) Presenilin PF01080.17 CDJ50917.1 - 0.0026 16.6 8.7 0.0026 16.6 8.7 2.2 2 0 0 2 2 2 1 Presenilin PA26 PF04636.13 CDJ50917.1 - 0.046 12.6 5.4 0.071 12.0 5.4 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SID-1_RNA_chan PF13965.6 CDJ50917.1 - 0.066 11.6 0.6 0.092 11.1 0.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Connexin PF00029.19 CDJ50917.1 - 0.083 12.6 4.5 0.15 11.8 4.5 1.3 1 0 0 1 1 1 0 Connexin DUF853 PF05872.12 CDJ50917.1 - 0.094 11.3 9.6 0.18 10.4 9.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) ALMT PF11744.8 CDJ50917.1 - 0.21 10.4 8.5 0.37 9.6 8.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Nha1_C PF08619.10 CDJ50917.1 - 0.23 10.6 18.6 1.5 7.9 11.4 2.3 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus CPSF100_C PF13299.6 CDJ50917.1 - 0.43 10.8 15.4 4.5 7.4 11.5 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Folate_carrier PF01770.18 CDJ50917.1 - 0.58 8.8 3.0 1 8.0 3.0 1.4 1 0 0 1 1 1 0 Reduced folate carrier Ndc1_Nup PF09531.10 CDJ50917.1 - 1 8.0 18.6 0.16 10.6 8.6 2.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup CSG2 PF16965.5 CDJ50917.1 - 1.2 8.0 4.1 2 7.3 4.1 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Serinc PF03348.15 CDJ50917.1 - 1.4 7.7 4.6 2.9 6.7 4.6 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) SPX PF03105.19 CDJ50917.1 - 2.5 7.9 24.6 0.6 10.0 15.6 2.4 2 1 0 2 2 2 0 SPX domain RP-C_C PF11800.8 CDJ50917.1 - 2.7 8.0 18.2 8.9 6.3 14.4 2.6 2 0 0 2 2 2 0 Replication protein C C-terminal region Otopetrin PF03189.13 CDJ50917.1 - 3.9 6.2 7.8 0.56 9.0 4.0 1.4 2 0 0 2 2 2 0 Otopetrin DUF4746 PF15928.5 CDJ50917.1 - 4.7 6.6 12.6 8.2 5.8 12.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Band_3_cyto PF07565.13 CDJ50917.1 - 5.9 6.6 15.4 0.23 11.2 9.5 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PAT1 PF09770.9 CDJ50917.1 - 6.4 4.9 31.5 11 4.2 31.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EPL1 PF10513.9 CDJ50917.1 - 6.6 7.1 19.4 3.1 8.2 15.3 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like eIF-3_zeta PF05091.12 CDJ50917.1 - 6.6 5.6 20.6 9.8 5.0 20.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.6 CDJ50918.1 - 0.29 9.5 5.9 0.34 9.3 5.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MDM10 PF12519.8 CDJ50918.1 - 1 8.2 17.9 1.2 7.9 17.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4667 PF15700.5 CDJ50918.1 - 3.7 7.6 23.1 4.3 7.4 23.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) DUF3474 PF11960.8 CDJ50918.1 - 3.7 7.7 5.8 5.4 7.2 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) ORC5_C PF14630.6 CDJ50920.1 - 7.1e-16 58.5 0.1 7.1e-16 58.5 0.1 3.6 3 2 0 3 3 3 1 Origin recognition complex (ORC) subunit 5 C-terminus DUF3446 PF11928.8 CDJ50920.1 - 0.0044 17.3 0.7 0.0044 17.3 0.7 8.4 7 2 2 9 9 9 1 Early growth response N-terminal domain ABC_tran PF00005.27 CDJ50920.1 - 0.012 16.2 0.6 0.095 13.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 CDJ50920.1 - 0.02 15.2 4.2 0.62 10.3 0.0 3.3 2 1 1 3 3 3 0 AAA domain DUF2791 PF10923.8 CDJ50920.1 - 0.038 12.8 0.1 0.038 12.8 0.1 1.6 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) GAS PF13851.6 CDJ50920.1 - 0.27 10.5 19.2 0.012 14.9 8.2 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_33 PF13671.6 CDJ50920.1 - 0.84 9.8 0.0 0.84 9.8 0.0 3.6 3 2 1 4 4 4 0 AAA domain Es2 PF09751.9 CDJ50921.1 - 1.1e-09 38.6 27.2 1.4e-07 31.6 6.1 7.2 3 1 2 6 6 6 3 Nuclear protein Es2 TFIIA PF03153.13 CDJ50921.1 - 0.0041 17.2 58.3 0.0041 17.2 58.3 6.1 1 1 3 5 5 5 1 Transcription factor IIA, alpha/beta subunit adh_short_C2 PF13561.6 CDJ50922.1 - 4.1e-46 157.4 0.0 9.3e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ50922.1 - 4.7e-09 36.0 0.7 1.1e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Enoyl_reductase PF12241.8 CDJ50922.1 - 0.0011 18.3 0.1 0.53 9.6 0.0 2.3 1 1 1 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region Es2 PF09751.9 CDJ50924.1 - 0.36 10.5 23.9 0.55 9.9 23.9 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 Peptidase_S8 PF00082.22 CDJ50926.1 - 5e-05 22.7 0.3 5e-05 22.7 0.3 3.2 1 1 1 2 2 2 1 Subtilase family SPX PF03105.19 CDJ50926.1 - 3.5 7.4 15.2 6.1 6.6 15.2 1.5 1 1 0 1 1 1 0 SPX domain RskA PF10099.9 CDJ50927.1 - 0.0001 22.7 18.4 0.0001 22.7 18.4 3.8 1 1 3 4 4 4 1 Anti-sigma-K factor rskA NnrS PF05940.12 CDJ50927.1 - 0.0085 15.5 18.8 0.012 15.0 18.8 1.1 1 0 0 1 1 1 1 NnrS protein MPM1 PF17234.2 CDJ50927.1 - 0.015 15.6 3.9 0.028 14.7 0.9 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Spt20 PF12090.8 CDJ50927.1 - 0.75 9.4 36.3 1.5 8.3 20.8 2.3 2 0 0 2 2 2 0 Spt20 family MKT1_N PF12247.8 CDJ50927.1 - 0.98 9.8 6.3 0.55 10.6 0.7 2.3 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication DUF4834 PF16118.5 CDJ50927.1 - 6.1 7.9 11.4 1.5 9.8 5.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) RXT2_N PF08595.11 CDJ50928.1 - 0.88 9.6 11.3 0.86 9.6 4.2 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal SpoIIP PF07454.11 CDJ50928.1 - 1.1 8.7 20.8 0.55 9.6 8.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 CDJ50928.1 - 1.2 9.4 14.9 0.84 9.8 5.5 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 CDJ50928.1 - 1.3 7.3 14.6 0.73 8.1 8.0 1.9 2 0 0 2 2 2 0 CDC45-like protein Vfa1 PF08432.10 CDJ50928.1 - 1.3 9.3 17.7 0.13 12.6 6.6 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 ORC_WH_C PF18137.1 CDJ50928.1 - 1.4 9.0 15.3 2.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal RR_TM4-6 PF06459.12 CDJ50928.1 - 1.5 8.5 24.0 0.53 10.1 12.2 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Dehalogenase PF13486.6 CDJ50928.1 - 1.8 7.9 9.6 0.045 13.1 1.9 1.8 2 0 0 2 2 2 0 Reductive dehalogenase subunit BORG_CEP PF14957.6 CDJ50928.1 - 2.3 9.4 15.5 3.2 8.9 6.0 2.3 2 0 0 2 2 2 0 Cdc42 effector RSRP PF17069.5 CDJ50928.1 - 2.3 7.7 4.2 4.1 6.9 4.2 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 TRAP_alpha PF03896.16 CDJ50928.1 - 3 7.0 10.8 10 5.2 7.0 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.8 CDJ50928.1 - 3.6 6.3 20.9 0.6 8.8 8.9 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4746 PF15928.5 CDJ50928.1 - 4 6.8 20.4 0.32 10.4 9.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) FAM60A PF15396.6 CDJ50928.1 - 6.3 6.7 12.6 2 8.4 4.4 2.1 2 0 0 2 2 2 0 Protein Family FAM60A CCSAP PF15748.5 CDJ50928.1 - 8.1 6.5 27.6 0.93 9.6 13.9 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated CSG2 PF16965.5 CDJ50929.1 - 0.0056 15.7 18.1 0.0056 15.7 18.1 5.6 3 2 3 6 6 6 2 Ceramide synthase regulator YbgS PF13985.6 CDJ50930.1 - 0.78 10.0 16.3 0.74 10.1 15.7 1.3 1 1 0 1 1 1 0 YbgS-like protein Zip PF02535.22 CDJ50930.1 - 4.4 6.4 7.2 5.4 6.1 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TPPII_N PF12583.8 CDJ50930.1 - 5.3 7.6 18.9 6.7 7.3 18.9 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal ASFV_J13L PF05568.11 CDJ50930.1 - 6.7 6.4 10.7 8.6 6.1 10.7 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Caskin1-CID PF16600.5 CDJ50930.1 - 6.9 7.3 10.2 8.1 7.1 9.2 1.7 1 1 0 1 1 1 0 Caskin1 CASK-interaction domain RT_RNaseH PF17917.1 CDJ50932.1 - 4.3e-28 97.7 0.0 8.9e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ50932.1 - 1.5e-27 95.6 0.0 3.5e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ50932.1 - 1.1e-06 28.3 0.8 0.00012 21.7 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 CDJ50932.1 - 4.8e-06 26.4 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_3 PF13456.6 CDJ50932.1 - 0.00026 20.8 0.0 0.00064 19.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like DUF4667 PF15700.5 CDJ50933.1 - 0.97 9.5 29.5 3.8 7.5 7.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) M16C_assoc PF08367.11 CDJ50933.1 - 3.4 6.7 8.9 0.045 12.9 2.0 1.4 2 0 0 2 2 2 0 Peptidase M16C associated Kinesin PF00225.23 CDJ50934.1 - 1.5e-64 218.0 1.7 1.5e-64 218.0 1.7 2.4 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ50934.1 - 2.6e-22 79.4 2.1 8.2e-22 77.8 0.0 2.6 2 1 0 2 2 2 1 Microtubule binding SR-25 PF10500.9 CDJ50934.1 - 1.7e-05 24.6 75.1 0.014 15.0 6.1 4.2 4 0 0 4 4 4 4 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ50934.1 - 0.0022 17.0 6.3 0.0022 17.0 6.3 2.4 2 1 0 2 2 2 1 Golgi-body localisation protein domain BUD22 PF09073.10 CDJ50934.1 - 0.0095 15.3 27.0 0.2 10.9 14.3 2.4 2 1 0 2 2 2 2 BUD22 Peptidase_S64 PF08192.11 CDJ50934.1 - 0.99 7.8 28.7 0.51 8.8 11.3 2.1 2 0 0 2 2 2 0 Peptidase family S64 SPX PF03105.19 CDJ50934.1 - 2.5 7.9 34.7 1.7e+03 -1.4 34.8 2.2 1 1 0 1 1 1 0 SPX domain DUF4746 PF15928.5 CDJ50934.1 - 2.9 7.2 11.4 4.5 6.6 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ribosomal_60s PF00428.19 CDJ50934.1 - 3.2 8.4 9.1 0.35 11.5 0.5 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein SpoIIIAH PF12685.7 CDJ50934.1 - 4.9 6.9 23.7 0.42 10.4 9.2 2.7 2 1 0 2 2 2 0 SpoIIIAH-like protein SAPS PF04499.15 CDJ50934.1 - 9.3 4.9 16.4 43 2.7 0.0 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein TIM PF00121.18 CDJ50935.1 - 1.8e-65 220.7 0.1 2e-65 220.6 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 CDJ50935.1 - 0.0073 15.8 0.2 0.018 14.5 0.2 1.6 1 1 1 2 2 2 1 CutC family SAVED PF18145.1 CDJ50935.1 - 0.032 14.0 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain MS_channel PF00924.18 CDJ50936.1 - 8e-09 35.3 2.5 5.1e-08 32.7 1.8 2.1 1 1 1 2 2 2 1 Mechanosensitive ion channel SUIM_assoc PF16619.5 CDJ50936.1 - 0.00098 19.1 6.3 0.00098 19.1 6.3 5.1 4 1 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 DUF1700 PF08006.11 CDJ50936.1 - 3.8 7.0 7.0 6.7 6.2 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) AAA_6 PF12774.7 CDJ50938.1 - 1.8e-145 484.0 0.4 1e-142 475.0 0.0 4.1 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CDJ50938.1 - 1.8e-130 436.3 5.3 1.8e-130 436.3 5.3 3.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CDJ50938.1 - 2.9e-115 385.6 6.5 2.9e-115 385.6 6.5 6.1 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CDJ50938.1 - 9.6e-87 290.6 0.1 3.2e-86 288.9 0.1 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ50938.1 - 7.9e-78 260.6 0.4 7.9e-78 260.6 0.4 2.7 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDJ50938.1 - 1.2e-54 184.6 0.1 4.1e-49 166.6 0.0 4.0 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_C PF18199.1 CDJ50938.1 - 2.8e-51 174.6 0.5 2.4e-29 102.5 0.0 3.4 2 1 1 3 3 3 2 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CDJ50938.1 - 1.2e-49 168.3 0.0 2.8e-49 167.1 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ50938.1 - 2.9e-38 130.6 0.0 2.5e-37 127.6 0.0 2.8 3 0 0 3 3 1 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CDJ50938.1 - 1.9e-28 99.5 15.6 1.9e-28 99.5 15.6 2.4 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CDJ50938.1 - 5.7e-21 75.0 0.1 2.7e-07 30.6 0.0 5.9 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDJ50938.1 - 3.5e-20 72.4 2.3 1.5e-19 70.3 0.2 3.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ50938.1 - 2.6e-19 69.3 1.0 3.1e-18 65.8 0.0 3.2 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 CDJ50938.1 - 1.6e-06 28.5 2.4 0.76 10.2 0.0 5.5 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ50938.1 - 1.7e-05 25.3 9.4 1.1 9.6 0.0 7.5 7 1 0 7 7 7 1 AAA ATPase domain AAA_18 PF13238.6 CDJ50938.1 - 0.0052 17.3 0.6 7 7.2 0.0 4.5 4 0 0 4 4 3 0 AAA domain T2SSE PF00437.20 CDJ50938.1 - 0.014 14.4 0.1 0.11 11.5 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 CDJ50938.1 - 0.035 14.2 0.1 0.37 10.9 0.0 2.9 3 0 0 3 3 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 CDJ50938.1 - 0.047 14.1 0.5 15 6.0 0.0 3.9 3 0 0 3 3 3 0 RNA helicase AAA_29 PF13555.6 CDJ50938.1 - 0.056 13.2 1.9 0.71 9.7 0.1 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.6 CDJ50938.1 - 0.06 13.5 1.3 3.4 7.8 0.0 3.4 3 0 0 3 3 2 0 AAA domain RuvB_N PF05496.12 CDJ50938.1 - 0.067 12.9 0.0 27 4.5 0.0 3.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CDJ50938.1 - 0.068 12.5 0.4 0.73 9.2 0.0 2.9 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Nab2 PF11517.8 CDJ50938.1 - 0.086 13.1 0.1 0.65 10.3 0.0 2.5 2 0 0 2 2 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) AAA_22 PF13401.6 CDJ50938.1 - 0.25 11.6 14.0 20 5.5 0.1 6.8 9 0 0 9 9 4 0 AAA domain AAA_28 PF13521.6 CDJ50938.1 - 0.59 10.4 4.0 12 6.1 0.0 4.2 4 0 0 4 4 3 0 AAA domain AAA_19 PF13245.6 CDJ50938.1 - 1.9 8.8 10.3 17 5.7 0.0 4.9 5 0 0 5 5 4 0 AAA domain Mac PF12464.8 CDJ50938.1 - 7.9 6.8 6.8 2.3 8.6 0.1 3.5 3 0 0 3 3 2 0 Maltose acetyltransferase AAA_30 PF13604.6 CDJ50938.1 - 9.2 5.9 8.7 7.8 6.2 0.1 3.7 4 0 0 4 4 4 0 AAA domain DHC_N1 PF08385.12 CDJ50939.1 - 0.11 11.1 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Proteasome PF00227.26 CDJ50940.1 - 1.4e-47 161.6 0.4 2.7e-47 160.7 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ50940.1 - 5.9e-11 41.8 0.0 1.1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature betaPIX_CC PF16523.5 CDJ50940.1 - 0.55 10.1 9.0 1 9.3 9.0 1.4 1 0 0 1 1 1 0 betaPIX coiled coil Cluap1 PF10234.9 CDJ50940.1 - 0.69 9.3 9.6 1.1 8.5 9.6 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 APG6_N PF17675.1 CDJ50940.1 - 1.9 9.0 10.2 3.9 8.0 10.2 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 CDJ50941.1 - 8.3e-34 116.6 2.4 1.5e-32 112.5 0.0 2.2 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family EPL1 PF10513.9 CDJ50941.1 - 0.19 12.1 4.5 2.9 8.3 1.7 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Tsg PF04668.12 CDJ50941.1 - 2.4 8.9 7.0 1.3 9.7 0.0 2.9 3 0 0 3 3 3 0 Twisted gastrulation (Tsg) protein conserved region Suf PF05843.14 CDJ50941.1 - 2.4 8.1 13.8 6.9 6.6 0.2 2.8 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 CDJ50941.1 - 3.2 7.8 11.6 5.1 7.1 5.6 2.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4834 PF16118.5 CDJ50941.1 - 4.2 8.4 12.8 5 8.1 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CDC14 PF08045.11 CDJ50941.1 - 6.4 5.8 7.2 2.7 7.0 0.1 2.2 2 0 0 2 2 2 0 Cell division control protein 14, SIN component Dfp1_Him1_M PF08630.10 CDJ50941.1 - 7.6 6.8 8.3 15 5.8 0.1 3.1 3 0 0 3 3 3 0 Dfp1/Him1, central region MMR1 PF08505.10 CDJ50941.1 - 9.7 6.4 9.3 5.4 7.2 3.1 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 CDJ50941.1 - 9.8 4.8 9.0 6.3 5.5 2.9 2.2 2 0 0 2 2 2 0 Presenilin V_ATPase_I PF01496.19 CDJ50942.1 - 1.4e-57 195.3 0.8 2.9e-57 194.2 0.8 1.5 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF2722 PF10846.8 CDJ50942.1 - 0.00046 19.3 1.3 0.00046 19.3 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ50942.1 - 0.051 13.6 13.5 0.064 13.2 13.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRR18 PF15671.5 CDJ50942.1 - 0.52 10.2 8.7 0.71 9.7 8.7 1.1 1 0 0 1 1 1 0 Proline-rich protein family 18 DUF3138 PF11336.8 CDJ50942.1 - 1.3 7.6 4.8 1.9 7.0 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Suf PF05843.14 CDJ50942.1 - 2.8 7.8 7.4 4 7.4 7.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PIH1_CS PF18201.1 CDJ50943.1 - 8e-05 23.0 0.0 0.0005 20.4 0.0 2.2 1 1 1 2 2 2 1 PIH1 CS-like domain DUF4175 PF13779.6 CDJ50943.1 - 0.031 12.2 67.9 0.042 11.8 67.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.9 CDJ50943.1 - 0.88 7.8 54.1 1.2 7.3 54.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Velvet PF11754.8 CDJ50943.1 - 1.6 8.6 28.3 3.2 7.6 28.3 1.5 1 0 0 1 1 1 0 Velvet factor Hid1 PF12722.7 CDJ50943.1 - 3.8 5.5 29.9 5.2 5.1 29.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Kelch_1 PF01344.25 CDJ50944.1 - 4.8e-38 128.5 3.5 1.8e-09 37.1 0.0 6.6 5 1 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 CDJ50944.1 - 5.5e-30 102.2 9.9 3e-06 27.0 0.0 7.2 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CDJ50944.1 - 3.2e-29 100.6 19.9 1.9e-05 24.8 0.3 9.1 8 2 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ50944.1 - 1.8e-27 94.7 6.8 3.6e-06 27.1 0.0 6.4 4 2 1 5 5 5 5 Kelch motif Kelch_4 PF13418.6 CDJ50944.1 - 2.4e-25 88.3 12.3 5e-05 23.2 0.0 6.7 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ50944.1 - 5.6e-24 83.7 2.1 1.6e-05 24.8 0.0 6.2 6 0 0 6 6 6 5 Kelch motif BTB PF00651.31 CDJ50944.1 - 5.2e-06 26.7 0.0 8.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SPX PF03105.19 CDJ50944.1 - 0.064 13.2 3.0 0.085 12.8 3.0 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ50944.1 - 0.32 9.8 5.5 0.42 9.4 5.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ50944.1 - 2.7 6.4 12.4 3.7 6.0 12.4 1.1 1 0 0 1 1 1 0 Macoilin family WES_acyltransf PF03007.16 CDJ50945.1 - 0.12 12.1 4.4 0.18 11.6 4.4 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain CNDH2_M PF16869.5 CDJ50945.1 - 0.12 13.0 7.0 0.13 12.9 7.0 1.1 1 0 0 1 1 1 0 PF16858 SpoIIP PF07454.11 CDJ50945.1 - 1.2 8.5 11.5 1.2 8.5 11.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2722 PF10846.8 CDJ50945.1 - 1.3 7.8 24.5 1.4 7.8 24.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ50945.1 - 2 9.1 20.0 2.2 8.9 20.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S49_N PF08496.10 CDJ50945.1 - 2.1 8.4 10.5 2.2 8.3 10.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.12 CDJ50945.1 - 3.1 7.5 12.9 2.9 7.7 12.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CDJ50945.1 - 3.1 7.9 10.9 3.5 7.7 10.9 1.1 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.16 CDJ50945.1 - 3.3 7.2 9.0 3.7 7.0 9.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4746 PF15928.5 CDJ50945.1 - 3.5 7.0 9.7 3.6 6.9 9.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Neur_chan_memb PF02932.16 CDJ50945.1 - 4.2 7.4 9.0 4.1 7.4 9.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Orf78 PF06024.12 CDJ50945.1 - 4.4 7.7 6.1 5.9 7.2 6.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) ALMT PF11744.8 CDJ50945.1 - 4.8 5.9 11.1 5.3 5.8 11.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DDRGK PF09756.9 CDJ50945.1 - 4.9 6.7 20.3 5.5 6.5 20.3 1.1 1 0 0 1 1 1 0 DDRGK domain CPSF100_C PF13299.6 CDJ50945.1 - 5.9 7.0 11.3 6.6 6.9 11.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4834 PF16118.5 CDJ50945.1 - 5.9 7.9 14.7 8.5 7.4 14.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ50945.1 - 6.9 6.3 9.2 8.1 6.1 9.2 1.1 1 0 0 1 1 1 0 FAM176 family CTU2 PF10288.9 CDJ50945.1 - 7 6.9 11.6 7.8 6.8 11.6 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Spore_coat_CotO PF14153.6 CDJ50945.1 - 7.3 6.5 18.9 8.3 6.3 18.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF4637 PF15470.6 CDJ50945.1 - 7.5 6.3 11.5 8.6 6.1 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RED_N PF07808.13 CDJ50945.1 - 7.8 6.0 15.5 8.9 5.8 15.5 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region CLN3 PF02487.17 CDJ50945.1 - 7.9 5.4 9.7 8.5 5.3 9.7 1.0 1 0 0 1 1 1 0 CLN3 protein EOS1 PF12326.8 CDJ50945.1 - 8.4 6.3 8.0 11 6.0 8.0 1.1 1 0 0 1 1 1 0 N-glycosylation protein EIIBC-GUT_N PF03612.14 CDJ50945.1 - 8.9 6.0 12.1 10 5.8 12.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 CDJ50945.1 - 9.1 4.9 16.3 9.2 4.9 16.3 1.0 1 0 0 1 1 1 0 Presenilin Membralin PF09746.9 CDJ50945.1 - 9.4 5.2 7.4 9.6 5.1 7.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 CDJ50945.1 - 9.4 6.2 18.5 10 6.1 18.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Cript PF10235.9 CDJ50946.1 - 6.9e-05 23.3 1.3 6.9e-05 23.3 1.3 1.8 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT GFA PF04828.14 CDJ50946.1 - 0.025 14.9 0.7 0.045 14.1 0.7 1.5 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme PEN-2 PF10251.9 CDJ50946.1 - 0.031 14.7 0.0 0.045 14.2 0.0 1.2 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase EF-hand_7 PF13499.6 CDJ50947.1 - 5.6e-27 94.0 0.5 3.4e-15 56.2 0.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ50947.1 - 2.6e-24 82.9 2.8 7.1e-07 28.3 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDJ50947.1 - 6.1e-21 72.5 6.5 3.4e-06 26.5 0.0 4.8 5 1 0 5 5 4 4 EF-hand domain EF-hand_8 PF13833.6 CDJ50947.1 - 4.9e-19 67.9 4.7 9.3e-11 41.4 0.1 3.6 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CDJ50947.1 - 5.9e-12 45.7 0.0 5.7e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ50947.1 - 2.4e-09 36.2 7.1 9.7e-05 21.7 0.3 4.3 4 1 1 5 5 5 2 EF hand EF-hand_4 PF12763.7 CDJ50947.1 - 0.001 19.0 0.4 0.041 13.8 0.1 2.8 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 CDJ50947.1 - 0.012 15.6 0.1 0.59 10.1 0.0 2.7 2 1 1 3 3 3 0 Tellurite resistance protein TerB TFIIA PF03153.13 CDJ50947.1 - 0.033 14.2 3.0 0.044 13.8 3.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3008 PF11450.8 CDJ50947.1 - 0.045 13.9 0.5 0.045 13.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) SPARC_Ca_bdg PF10591.9 CDJ50947.1 - 0.31 11.4 0.8 4.7 7.6 0.0 2.6 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 CDJ50947.1 - 1.1 9.7 3.7 4.1 7.8 0.1 2.7 3 0 0 3 3 2 0 EF-hand domain Vps39_2 PF10367.9 CDJ50948.1 - 8.3e-18 64.8 0.0 8.3e-18 64.8 0.0 4.5 5 0 0 5 5 5 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 CDJ50948.1 - 2.5e-05 24.2 2.6 0.00064 19.6 1.4 3.5 2 1 1 3 3 3 1 Region in Clathrin and VPS Spt20 PF12090.8 CDJ50948.1 - 0.0015 18.2 8.7 0.0015 18.2 8.7 4.3 3 1 1 4 4 4 2 Spt20 family DUF2722 PF10846.8 CDJ50948.1 - 0.0019 17.2 4.1 0.0019 17.2 4.1 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ50948.1 - 0.054 13.8 0.4 0.054 13.8 0.4 8.7 5 3 3 8 8 8 0 Anti-sigma-K factor rskA GRP PF07172.11 CDJ50948.1 - 9.2 7.0 6.4 16 6.3 0.1 3.4 3 0 0 3 3 3 0 Glycine rich protein family RskA PF10099.9 CDJ50949.1 - 0.0029 17.9 10.0 0.0029 17.9 10.0 8.0 2 2 2 4 4 4 1 Anti-sigma-K factor rskA SART-1 PF03343.13 CDJ50951.1 - 9.9 4.6 38.1 15 3.9 38.1 1.3 1 0 0 1 1 1 0 SART-1 family RskA PF10099.9 CDJ50952.1 - 0.036 14.3 0.4 0.036 14.3 0.4 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TMEM208_SND2 PF05620.11 CDJ50952.1 - 3.6 7.3 5.7 2.3 8.0 3.1 1.9 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 CCDC53 PF10152.9 CDJ50952.1 - 8.3 6.8 13.6 2.8 8.3 3.4 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex PAP2 PF01569.21 CDJ50953.1 - 2.7e-23 82.2 1.9 2.7e-23 82.2 1.9 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CDJ50953.1 - 0.003 18.1 0.8 0.003 18.1 0.8 2.7 3 0 0 3 3 3 1 PAP2 superfamily C-terminal Band_7 PF01145.25 CDJ50954.1 - 3.7e-27 95.5 0.3 9e-27 94.2 0.1 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CDJ50954.1 - 4e-05 22.8 1.7 5e-05 22.5 1.7 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 CDJ50954.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family WHAMM-JMY_N PF15920.5 CDJ50954.1 - 0.097 12.5 0.3 0.24 11.3 0.3 1.5 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated Mannitol_dh PF01232.23 CDJ50954.1 - 0.12 12.5 0.5 0.21 11.7 0.5 1.4 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Lysis_col PF02402.16 CDJ50955.1 - 0.13 11.9 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Lysis protein SET PF00856.28 CDJ50956.1 - 5.3e-05 23.7 3.3 0.023 15.1 0.0 3.9 3 1 0 4 4 4 2 SET domain DUF2722 PF10846.8 CDJ50956.1 - 0.0098 14.9 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ50956.1 - 0.22 11.1 6.7 0.47 10.0 6.7 1.4 1 0 0 1 1 1 0 Spt20 family Arm PF00514.23 CDJ50957.1 - 0.079 13.0 0.1 0.5 10.5 0.0 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat SAS-6_N PF16531.5 CDJ50958.1 - 1.1e-28 99.7 3.2 1.7e-28 99.0 3.2 1.4 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal TIP49 PF06068.13 CDJ50959.1 - 1.2e-157 524.7 0.0 1.4e-157 524.4 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CDJ50959.1 - 2.2e-16 59.7 0.9 5.2e-15 55.3 0.9 2.9 1 1 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CDJ50959.1 - 1.2e-12 48.4 0.0 1.6e-08 35.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ50959.1 - 1.2e-09 38.1 0.2 1.3e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ50959.1 - 2.3e-06 27.9 0.2 0.031 14.6 0.1 2.8 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 CDJ50959.1 - 9.5e-06 25.7 0.1 0.0015 18.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ50959.1 - 1.1e-05 25.9 0.0 0.0018 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 CDJ50959.1 - 0.00019 21.8 0.1 0.079 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDJ50959.1 - 0.00066 19.1 0.1 0.027 13.9 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CDJ50959.1 - 0.00076 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CDJ50959.1 - 0.0009 19.0 0.0 0.48 10.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 CDJ50959.1 - 0.0011 19.5 0.0 0.0035 17.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 CDJ50959.1 - 0.0034 17.1 0.1 0.007 16.1 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CDJ50959.1 - 0.0035 16.9 0.0 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region DnaB_C PF03796.15 CDJ50959.1 - 0.0037 16.6 0.0 0.0077 15.6 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Torsin PF06309.11 CDJ50959.1 - 0.0055 16.8 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_28 PF13521.6 CDJ50959.1 - 0.0058 16.9 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ50959.1 - 0.0068 16.6 0.0 0.036 14.2 0.0 2.1 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 CDJ50959.1 - 0.0099 15.2 0.1 0.029 13.7 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.6 CDJ50959.1 - 0.01 15.9 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CDJ50959.1 - 0.011 15.8 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.17 CDJ50959.1 - 0.024 13.7 0.4 0.078 12.0 0.1 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 CDJ50959.1 - 0.025 14.6 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 CDJ50959.1 - 0.026 14.3 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CDJ50959.1 - 0.029 13.6 0.0 0.061 12.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CDJ50959.1 - 0.031 14.0 0.0 0.49 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CDJ50959.1 - 0.04 14.3 0.0 0.095 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 CDJ50959.1 - 0.047 13.1 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein NTPase_1 PF03266.15 CDJ50959.1 - 0.052 13.5 0.1 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 NTPase PIF1 PF05970.14 CDJ50959.1 - 0.054 12.7 0.0 3 6.9 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Rad17 PF03215.15 CDJ50959.1 - 0.054 13.4 0.4 0.16 11.9 0.0 1.9 2 1 0 2 2 1 0 Rad17 P-loop domain AAA_17 PF13207.6 CDJ50959.1 - 0.06 13.8 0.1 0.43 11.0 0.0 2.3 2 1 1 3 3 3 0 AAA domain NACHT PF05729.12 CDJ50959.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SLD3 PF08639.10 CDJ50960.1 - 0.27 10.0 20.4 0.31 9.8 20.4 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 FAM60A PF15396.6 CDJ50960.1 - 6.4 6.7 22.2 7.4 6.5 22.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Pinin_SDK_memA PF04696.13 CDJ50961.1 - 0.28 11.2 34.0 0.65 10.1 8.3 2.4 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DDRGK PF09756.9 CDJ50961.1 - 7.1 6.2 26.7 0.66 9.5 5.1 2.2 2 0 0 2 2 2 0 DDRGK domain WD40 PF00400.32 CDJ50962.1 - 3.3e-23 81.5 12.9 0.00019 22.1 0.1 11.0 10 1 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ50962.1 - 2.8e-08 33.9 0.0 0.073 13.4 0.0 5.3 6 0 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ50962.1 - 0.00047 18.9 1.8 0.0016 17.2 0.5 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Frtz PF11768.8 CDJ50962.1 - 0.007 14.7 0.1 0.016 13.5 0.0 1.5 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz RcnB PF11776.8 CDJ50962.1 - 0.062 13.4 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator Ge1_WD40 PF16529.5 CDJ50962.1 - 0.081 11.9 1.9 0.19 10.6 0.3 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2722 PF10846.8 CDJ50963.1 - 0.018 14.0 23.1 0.088 11.7 16.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) MMR1 PF08505.10 CDJ50963.1 - 1.3 9.3 17.3 0.26 11.6 9.6 2.4 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Lin-8 PF03353.15 CDJ50963.1 - 1.3 8.5 13.7 0.09 12.3 5.3 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Folate_carrier PF01770.18 CDJ50963.1 - 3.6 6.2 5.9 1 8.0 2.8 1.5 2 0 0 2 2 2 0 Reduced folate carrier RCC1 PF00415.18 CDJ50964.1 - 1.2e-12 48.2 10.0 1.4e-05 25.6 0.2 6.1 5 1 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ50964.1 - 4.7e-10 39.0 21.7 0.0035 17.1 4.9 5.6 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Presenilin PF01080.17 CDJ50964.1 - 5.7e-05 22.1 4.9 5.7e-05 22.1 4.9 3.1 3 0 0 3 3 3 1 Presenilin DUF4770 PF15994.5 CDJ50964.1 - 0.00034 20.9 4.4 0.00034 20.9 4.4 4.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4770) DUF2722 PF10846.8 CDJ50964.1 - 0.00043 19.4 9.2 0.00043 19.4 9.2 6.2 5 1 1 6 6 6 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ50964.1 - 0.0049 16.9 26.4 0.0049 16.9 26.4 3.5 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Pox_P35 PF03213.14 CDJ50964.1 - 0.0092 15.2 0.1 0.0092 15.2 0.1 2.5 4 0 0 4 4 4 1 Poxvirus P35 protein SAPS PF04499.15 CDJ50964.1 - 0.16 10.8 22.8 0.23 10.2 3.7 2.4 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 CDJ50964.1 - 0.3 10.9 31.7 0.1 12.4 3.0 3.3 3 0 0 3 3 3 0 SpoIIIAH-like protein Pex14_N PF04695.13 CDJ50964.1 - 2.5 8.7 75.7 0.041 14.5 10.8 4.5 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rhomboid PF01694.22 CDJ50965.1 - 1.9e-26 92.8 13.6 4e-26 91.8 13.6 1.5 1 0 0 1 1 1 1 Rhomboid family ETRAMP PF09716.10 CDJ50966.1 - 0.0056 16.7 4.9 0.078 13.1 0.0 3.8 3 0 0 3 3 3 1 Malarial early transcribed membrane protein (ETRAMP) K_channel_TID PF07941.11 CDJ50966.1 - 0.013 16.0 8.2 0.013 16.0 8.2 12.3 8 4 4 12 12 12 0 Potassium channel Kv1.4 tandem inactivation domain DUF2207 PF09972.9 CDJ50966.1 - 0.26 10.0 1.3 2.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Tau95_N PF17682.1 CDJ50966.1 - 4.3 7.5 9.5 3.9 7.7 0.3 3.5 3 0 0 3 3 3 0 Tau95 Triple barrel domain PRC2_HTH_1 PF18118.1 CDJ50966.1 - 6.4 7.6 15.0 6.7 7.6 3.2 3.5 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain tRNA_lig_CPD PF08302.11 CDJ50966.1 - 7.4 5.9 18.9 6.1 6.2 2.9 3.4 3 0 0 3 3 3 0 Fungal tRNA ligase phosphodiesterase domain COX15-CtaA PF02628.15 CDJ50967.1 - 1.1e-34 120.0 10.6 1.8e-23 83.2 1.1 2.7 2 1 1 3 3 3 2 Cytochrome oxidase assembly protein DUF773 PF05600.12 CDJ50967.1 - 1.5e-14 53.6 27.1 1.8e-12 46.8 14.4 2.1 1 1 1 2 2 2 2 CDK5 regulatory subunit-associated protein 3 UCR_6-4kD PF08997.10 CDJ50967.1 - 0.2 11.6 0.1 0.52 10.3 0.1 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein RAP1 PF07218.11 CDJ50967.1 - 1.7 6.8 7.4 2.3 6.4 7.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cadherin_C PF01049.17 CDJ50967.1 - 3.4 8.0 16.6 0.2 12.0 7.5 2.6 1 1 1 2 2 2 0 Cadherin cytoplasmic region DUF2722 PF10846.8 CDJ50969.1 - 0.00057 19.0 26.4 0.00073 18.6 8.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ50969.1 - 0.008 16.2 8.5 0.008 16.2 8.5 4.5 1 1 1 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ50969.1 - 0.012 15.6 50.8 0.22 11.5 18.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit OmpH PF03938.14 CDJ50969.1 - 0.017 15.5 7.6 0.017 15.5 7.6 3.0 2 1 1 3 3 2 0 Outer membrane protein (OmpH-like) KASH PF10541.9 CDJ50969.1 - 0.069 13.4 4.2 0.22 11.8 4.2 1.9 1 0 0 1 1 1 0 Nuclear envelope localisation domain DUF1764 PF08576.10 CDJ50969.1 - 0.17 12.8 7.7 2.1 9.3 2.3 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) SARAF PF06682.12 CDJ50969.1 - 0.37 10.4 17.3 1.1 8.8 8.6 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Activator_LAG-3 PF11498.8 CDJ50969.1 - 0.42 9.5 53.1 0.13 11.2 19.7 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Calici_coat_C PF08435.11 CDJ50969.1 - 0.44 10.0 7.5 0.097 12.2 0.7 2.1 2 0 0 2 2 2 0 Calicivirus coat protein C-terminal Hydin_ADK PF17213.3 CDJ50969.1 - 1.1 9.5 11.3 3.7 7.8 2.6 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain MMR1 PF08505.10 CDJ50969.1 - 2.3 8.5 18.4 2.6 8.3 5.4 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF702 PF05142.12 CDJ50969.1 - 2.3 8.7 12.1 1.6 9.2 2.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF702) SpoIIP PF07454.11 CDJ50969.1 - 3.1 7.2 9.6 1.1 8.6 2.2 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4667 PF15700.5 CDJ50969.1 - 3.4 7.7 10.8 2.9 7.9 8.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4667) EPL1 PF10513.9 CDJ50969.1 - 3.5 8.0 12.3 1.3 9.4 2.2 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like FAM60A PF15396.6 CDJ50969.1 - 3.6 7.5 6.9 11 6.0 1.8 2.1 2 0 0 2 2 2 0 Protein Family FAM60A ANAPC_CDC26 PF10471.9 CDJ50969.1 - 4.1 8.3 38.7 0.15 12.9 13.7 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF775 PF05603.12 CDJ50969.1 - 4.2 6.8 16.4 1.8 8.0 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF775) DUF4770 PF15994.5 CDJ50969.1 - 6.4 7.0 16.0 5.7 7.2 5.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) WD40 PF00400.32 CDJ50970.1 - 0.00017 22.3 0.0 0.00057 20.6 0.0 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat Tim54 PF11711.8 CDJ50970.1 - 0.019 13.8 5.9 0.032 13.0 5.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SID-1_RNA_chan PF13965.6 CDJ50970.1 - 0.047 12.1 0.2 0.04 12.3 0.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spt20 PF12090.8 CDJ50970.1 - 0.1 12.2 46.8 0.23 11.0 36.1 2.4 2 0 0 2 2 2 0 Spt20 family MecA PF05389.12 CDJ50970.1 - 0.13 11.9 5.7 0.24 11.0 5.7 1.5 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF572 PF04502.13 CDJ50970.1 - 0.17 11.5 10.9 0.21 11.2 10.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) GREB1 PF15782.5 CDJ50970.1 - 0.19 8.8 14.2 0.2 8.8 14.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF677 PF05055.12 CDJ50970.1 - 0.44 9.4 0.0 0.44 9.4 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF677) ALMT PF11744.8 CDJ50970.1 - 0.73 8.6 9.3 0.95 8.2 9.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter AAA_23 PF13476.6 CDJ50970.1 - 0.74 10.3 12.9 1.1 9.7 12.9 1.1 1 0 0 1 1 1 0 AAA domain DUF4746 PF15928.5 CDJ50970.1 - 0.92 8.9 6.7 1.2 8.5 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Otopetrin PF03189.13 CDJ50970.1 - 0.92 8.2 5.4 1.2 7.9 5.4 1.3 1 0 0 1 1 1 0 Otopetrin RR_TM4-6 PF06459.12 CDJ50970.1 - 1.4 8.7 14.6 2.2 8.0 14.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paramyxo_ncap PF00973.19 CDJ50970.1 - 1.4 7.7 6.1 1.8 7.4 6.1 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Peptidase_S64 PF08192.11 CDJ50970.1 - 1.6 7.1 11.0 2.2 6.7 11.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 AIF_C PF14721.6 CDJ50970.1 - 1.8 9.0 7.9 4.5 7.6 7.9 1.8 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SpoIIP PF07454.11 CDJ50970.1 - 1.9 7.9 14.9 3.2 7.1 14.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Membralin PF09746.9 CDJ50970.1 - 2.5 7.0 9.2 3.9 6.4 9.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein OATP PF03137.20 CDJ50970.1 - 2.8 6.1 6.4 4.1 5.6 6.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3180 PF11377.8 CDJ50970.1 - 3.2 7.9 39.8 0.37 10.9 1.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) CSG2 PF16965.5 CDJ50970.1 - 3.6 6.4 6.3 5.2 5.9 6.3 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Serinc PF03348.15 CDJ50970.1 - 4.4 6.1 6.9 5.7 5.7 6.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SLC12 PF03522.15 CDJ50970.1 - 5.1 6.0 17.7 7.2 5.5 17.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 LMBR1 PF04791.16 CDJ50970.1 - 5.6 5.8 5.3 7.2 5.4 5.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CbiM PF01891.16 CDJ50970.1 - 5.8 6.7 18.7 0.56 10.0 4.5 3.0 3 0 0 3 3 3 0 Cobalt uptake substrate-specific transmembrane region DUF1764 PF08576.10 CDJ50970.1 - 6.2 7.8 12.7 2.2 9.2 9.6 1.8 2 0 0 2 2 1 0 Eukaryotic protein of unknown function (DUF1764) DUF2828 PF11443.8 CDJ50970.1 - 6.5 4.7 15.5 10 4.1 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Dishevelled PF02377.15 CDJ50970.1 - 7.1 7.1 14.9 14 6.1 14.9 1.4 1 0 0 1 1 1 0 Dishevelled specific domain PAP2 PF01569.21 CDJ50971.1 - 0.14 11.9 0.4 0.78 9.5 0.0 2.5 2 0 0 2 2 2 0 PAP2 superfamily Nha1_C PF08619.10 CDJ50972.1 - 0.062 12.5 6.8 0.061 12.5 6.8 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Spt20 PF12090.8 CDJ50972.1 - 0.082 12.5 19.3 0.077 12.6 19.3 1.0 1 0 0 1 1 1 0 Spt20 family SieB PF14163.6 CDJ50972.1 - 0.12 11.9 0.8 0.14 11.7 0.8 1.0 1 0 0 1 1 1 0 Super-infection exclusion protein B MttA_Hcf106 PF02416.16 CDJ50972.1 - 0.12 11.7 1.6 0.19 11.1 1.6 1.6 1 1 0 1 1 1 0 mttA/Hcf106 family TERB2 PF15101.6 CDJ50972.1 - 0.14 12.2 7.3 0.16 12.0 7.3 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Med15 PF09606.10 CDJ50972.1 - 0.2 10.3 18.6 0.21 10.2 18.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BBS2_C PF14782.6 CDJ50972.1 - 0.2 10.4 5.4 0.19 10.4 5.4 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF4834 PF16118.5 CDJ50972.1 - 0.27 12.2 4.2 0.27 12.2 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ50972.1 - 1.1 9.2 18.1 1.1 9.1 18.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4574 PF15141.6 CDJ50972.1 - 1.3 8.9 7.4 1.7 8.6 7.4 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 NYD-SP28_assoc PF14775.6 CDJ50972.1 - 2.4 8.3 13.6 3 8.0 13.6 1.2 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF2722 PF10846.8 CDJ50972.1 - 7 5.5 18.5 8 5.3 18.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ50972.1 - 7.2 5.3 7.0 7.6 5.2 7.0 1.0 1 0 0 1 1 1 0 Presenilin DUF3801 PF12687.7 CDJ50973.1 - 0.0057 16.7 0.0 0.0057 16.7 0.0 4.3 2 2 1 3 3 3 1 Protein of unknown function (DUF3801) SARAF PF06682.12 CDJ50973.1 - 1.5 8.4 0.0 1.5 8.4 0.0 5.8 3 2 0 5 5 5 0 SOCE-associated regulatory factor of calcium homoeostasis PIP5K PF01504.18 CDJ50973.1 - 2 7.6 12.7 1.6 7.9 0.7 3.2 3 0 0 3 3 3 0 Phosphatidylinositol-4-phosphate 5-Kinase Shadoo PF14999.6 CDJ50974.1 - 0.082 13.0 4.5 0.12 12.5 4.5 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective LMBR1 PF04791.16 CDJ50975.1 - 4.3e-05 22.6 0.1 4.3e-05 22.6 0.1 3.3 1 1 2 3 3 2 2 LMBR1-like membrane protein TFIIA PF03153.13 CDJ50975.1 - 0.036 14.1 35.1 0.35 10.8 31.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Amastin PF07344.11 CDJ50975.1 - 0.059 13.2 6.3 2.8 7.8 2.4 2.6 2 1 0 2 2 2 0 Amastin surface glycoprotein CooC_C PF15976.5 CDJ50975.1 - 0.37 10.8 3.1 0.96 9.5 3.1 1.6 1 0 0 1 1 1 0 CS1-pili formation C-terminal DUF3481 PF11980.8 CDJ50975.1 - 0.78 9.5 4.5 0.44 10.3 0.1 2.5 3 0 0 3 3 3 0 C-terminal domain of neuropilin glycoprotein Sec62 PF03839.16 CDJ50975.1 - 1.2 8.6 5.3 5.3 6.5 5.6 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 Neur_chan_memb PF02932.16 CDJ50975.1 - 1.2 9.1 7.1 2.5 8.1 6.0 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4199 PF13858.6 CDJ50975.1 - 1.5 9.2 4.2 27 5.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) MAP17 PF15807.5 CDJ50975.1 - 2.9 8.1 9.6 1.5 9.0 0.2 2.8 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RR_TM4-6 PF06459.12 CDJ50975.1 - 8.5 6.1 11.9 46 3.7 8.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Rer1 PF03248.13 CDJ50975.1 - 8.6 6.1 6.1 1.6 8.4 1.3 2.1 2 0 0 2 2 2 0 Rer1 family Kringle PF00051.18 CDJ50977.1 - 2e-12 47.2 2.1 6.6e-12 45.6 2.1 1.9 1 0 0 1 1 1 1 Kringle domain Ephrin_rec_like PF07699.13 CDJ50977.1 - 3e-10 39.7 12.0 0.00011 21.9 0.8 2.7 2 0 0 2 2 2 2 Putative ephrin-receptor like RANK_CRD_2 PF18278.1 CDJ50977.1 - 0.0049 17.0 0.2 0.0049 17.0 0.2 2.3 2 0 0 2 2 2 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 MAR_sialic_bdg PF10564.9 CDJ50977.1 - 0.082 13.0 6.2 0.46 10.6 0.1 3.1 2 1 1 3 3 3 0 Sialic-acid binding micronemal adhesive repeat SR-25 PF10500.9 CDJ50978.1 - 2.8e-07 30.4 27.3 1.7e-05 24.6 16.1 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ50978.1 - 0.003 18.2 17.2 0.11 13.2 8.1 2.7 2 0 0 2 2 2 2 Immortalisation up-regulated protein PDCD2_C PF04194.13 CDJ50978.1 - 0.018 15.1 1.1 0.018 15.1 1.1 4.3 3 2 0 3 3 3 0 Programmed cell death protein 2, C-terminal putative domain DUF3295 PF11702.8 CDJ50978.1 - 0.8 9.0 36.5 0.011 15.1 24.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) Presenilin PF01080.17 CDJ50978.1 - 1.1 7.9 21.8 0.045 12.5 16.0 1.8 2 0 0 2 2 2 0 Presenilin SUIM_assoc PF16619.5 CDJ50978.1 - 2.2 8.4 44.1 28 4.9 0.0 6.1 2 2 2 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 BAF1_ABF1 PF04684.13 CDJ50978.1 - 2.7 7.0 26.0 0.56 9.2 22.6 1.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Cwf_Cwc_15 PF04889.12 CDJ50978.1 - 2.8 7.6 28.0 6.4 6.4 28.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 CDJ50979.1 - 8.4e-36 124.1 30.1 8.4e-36 124.1 30.1 2.4 2 1 0 2 2 2 1 SDA1 PPP4R2 PF09184.11 CDJ50979.1 - 0.52 9.8 16.1 1.4 8.4 16.1 1.8 1 0 0 1 1 1 0 PPP4R2 RskA PF10099.9 CDJ50979.1 - 5.7 7.2 28.4 0.97 9.7 14.8 3.0 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Endostatin PF06482.11 CDJ50980.1 - 0.0027 17.2 12.5 0.0038 16.7 12.5 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin CCSAP PF15748.5 CDJ50980.1 - 0.011 15.9 20.3 0.016 15.4 20.3 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ50980.1 - 0.014 15.3 7.3 0.017 14.9 7.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 CDJ50980.1 - 0.038 14.0 46.8 0.043 13.8 46.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF45 PF01863.17 CDJ50980.1 - 0.05 13.6 9.1 0.072 13.1 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF2126 PF09899.9 CDJ50980.1 - 0.073 11.1 6.2 0.092 10.8 6.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) MDM31_MDM32 PF08118.11 CDJ50980.1 - 0.088 11.5 4.4 0.13 10.9 4.4 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins CLN3 PF02487.17 CDJ50980.1 - 0.44 9.5 5.5 0.64 9.0 5.5 1.2 1 0 0 1 1 1 0 CLN3 protein SLC12 PF03522.15 CDJ50980.1 - 0.53 9.3 9.3 0.63 9.0 9.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Serinc PF03348.15 CDJ50980.1 - 0.71 8.7 1.8 0.77 8.6 1.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) PAT1 PF09770.9 CDJ50980.1 - 2.2 6.4 25.5 2.5 6.3 25.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4667 PF15700.5 CDJ50980.1 - 2.6 8.1 29.2 2.2 8.3 6.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Hid1 PF12722.7 CDJ50980.1 - 4 5.5 14.8 4.6 5.3 14.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein V_ATPase_I PF01496.19 CDJ50980.1 - 5.7 4.7 14.0 7.5 4.3 14.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 CDJ50980.1 - 7.1 5.3 10.5 11 4.8 10.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2828 PF11443.8 CDJ50980.1 - 9.5 4.2 14.0 13 3.8 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DSPc PF00782.20 CDJ50981.1 - 2.8e-18 66.0 0.0 1.7e-16 60.2 0.0 3.0 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain SUIM_assoc PF16619.5 CDJ50981.1 - 0.0084 16.2 0.0 0.0084 16.2 0.0 6.2 5 3 0 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 Y_phosphatase PF00102.27 CDJ50981.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Sacchrp_dh_NADP PF03435.18 CDJ50982.1 - 4.8e-14 52.7 0.1 1.7e-13 50.9 0.1 2.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF4834 PF16118.5 CDJ50982.1 - 0.0048 17.8 0.1 0.0048 17.8 0.1 4.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4834) CDC27 PF09507.10 CDJ50982.1 - 0.054 12.9 46.0 0.087 12.2 46.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Semialdhyde_dh PF01118.24 CDJ50982.1 - 0.46 10.9 1.6 0.56 10.7 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain SR-25 PF10500.9 CDJ50983.1 - 0.0016 18.1 9.3 0.0016 18.1 9.3 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein TT_ORF1 PF02956.14 CDJ50983.1 - 0.074 11.7 6.8 0.23 10.1 0.1 2.1 2 0 0 2 2 2 0 TT viral orf 1 Adipogenin PF15202.6 CDJ50983.1 - 0.085 12.9 0.7 0.17 11.9 0.7 1.5 1 0 0 1 1 1 0 Adipogenin MarC PF01914.17 CDJ50983.1 - 0.19 11.1 3.1 0.9 8.9 0.0 2.5 3 0 0 3 3 3 0 MarC family integral membrane protein DcuA_DcuB PF03605.14 CDJ50983.1 - 0.22 10.4 6.5 0.21 10.4 0.6 2.3 2 1 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter Med15 PF09606.10 CDJ50983.1 - 1.1 7.8 46.6 1.2 7.7 20.1 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4471 PF14740.6 CDJ50983.1 - 1.9 7.6 11.3 6.5 5.9 7.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Glyco_tran_28_C PF04101.16 CDJ50983.1 - 2.4 8.1 17.0 2.1 8.3 5.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain Zip PF02535.22 CDJ50983.1 - 3.2 6.9 6.7 0.38 9.9 0.1 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Peroxin-13_N PF04088.13 CDJ50983.1 - 3.6 7.8 17.7 4 7.7 1.7 3.0 2 1 1 3 3 3 0 Peroxin 13, N-terminal region EphA2_TM PF14575.6 CDJ50983.1 - 7.6 7.5 13.8 11 7.0 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Asparaginase_2 PF01112.18 CDJ50983.1 - 7.6 5.5 10.1 4.6 6.2 2.0 2.2 2 0 0 2 2 2 0 Asparaginase DUF4179 PF13786.6 CDJ50983.1 - 8.4 6.9 6.4 46 4.6 6.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Nop53 PF07767.11 CDJ50984.1 - 0.04 13.3 18.1 0.043 13.2 18.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Glyco_transf_29 PF00777.18 CDJ50984.1 - 0.045 13.2 1.8 0.059 12.8 1.8 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) DUF4757 PF15949.5 CDJ50984.1 - 0.97 9.9 20.3 1.3 9.5 20.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) DUF1501 PF07394.12 CDJ50984.1 - 1.1 8.2 11.6 1.2 8.1 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF3450 PF11932.8 CDJ50984.1 - 1.2 8.3 28.9 1.8 7.8 28.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 CDJ50984.1 - 1.7 8.2 20.0 1.9 8.0 20.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PBP_dimer PF03717.15 CDJ50984.1 - 1.9 8.8 10.3 2.5 8.4 10.3 1.1 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain Cellulose_synt PF03552.14 CDJ50984.1 - 3.3 6.1 6.3 4 5.8 6.3 1.1 1 0 0 1 1 1 0 Cellulose synthase SID-1_RNA_chan PF13965.6 CDJ50984.1 - 3.6 5.9 4.7 3.8 5.8 4.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MAJIN PF15077.6 CDJ50984.1 - 5.3 6.8 11.0 6.6 6.5 11.0 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF3332 PF11810.8 CDJ50984.1 - 6.6 6.3 7.1 9 5.9 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) DUF1645 PF07816.11 CDJ50985.1 - 0.0002 22.0 4.5 0.0002 22.0 4.5 4.9 3 2 0 3 3 3 1 Protein of unknown function (DUF1645) Presenilin PF01080.17 CDJ50985.1 - 0.00025 19.9 2.0 0.00025 19.9 2.0 4.2 3 1 1 4 4 4 1 Presenilin RPOL_N PF14700.6 CDJ50985.1 - 0.0004 19.9 1.2 0.0004 19.9 1.2 4.1 3 1 1 4 4 4 1 DNA-directed RNA polymerase N-terminal SR-25 PF10500.9 CDJ50985.1 - 0.00045 19.9 23.3 0.00045 19.9 23.3 4.4 3 2 0 4 4 4 1 Nuclear RNA-splicing-associated protein Utp14 PF04615.13 CDJ50985.1 - 0.0025 16.5 14.7 0.0025 16.5 14.7 2.9 2 1 0 2 2 2 1 Utp14 protein MID_MedPIWI PF18296.1 CDJ50985.1 - 0.0059 16.4 1.6 0.0059 16.4 1.6 4.2 3 1 0 3 3 3 1 MID domain of medPIWI Coilin_N PF15862.5 CDJ50985.1 - 0.012 15.4 7.4 0.012 15.4 7.4 5.2 3 1 2 5 5 5 0 Coilin N-terminus SUIM_assoc PF16619.5 CDJ50985.1 - 0.019 15.0 5.8 0.019 15.0 5.8 8.5 4 2 3 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 FA_desaturase PF00487.24 CDJ50985.1 - 0.29 10.9 0.0 0.29 10.9 0.0 3.8 3 1 1 4 4 4 0 Fatty acid desaturase FbpA PF05833.11 CDJ50986.1 - 3e-08 32.9 0.0 3e-08 32.9 0.0 10.7 9 3 1 10 10 10 3 Fibronectin-binding protein A N-terminus (FbpA) Presenilin PF01080.17 CDJ50986.1 - 0.0013 17.6 6.5 0.0013 17.6 6.5 9.3 5 2 3 8 8 8 2 Presenilin Ribosomal_60s PF00428.19 CDJ50986.1 - 0.0017 18.9 4.0 0.0017 18.9 4.0 14.6 13 3 0 13 13 13 4 60s Acidic ribosomal protein SUIM_assoc PF16619.5 CDJ50986.1 - 0.34 11.0 0.0 0.34 11.0 0.0 24.9 13 6 6 19 19 19 0 Unstructured region C-term to UIM in Ataxin3 DUF4179 PF13786.6 CDJ50986.1 - 3.6 8.1 0.0 3.6 8.1 0.0 7.8 9 1 0 9 9 9 0 Domain of unknown function (DUF4179) DUF755 PF05501.11 CDJ50987.1 - 0.00039 20.7 23.6 0.00055 20.2 23.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF755) CCDC24 PF15669.5 CDJ50987.1 - 0.0071 16.2 9.4 0.0082 16.0 9.4 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family DUF3482 PF11981.8 CDJ50987.1 - 0.017 14.5 0.3 0.018 14.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF702 PF05142.12 CDJ50987.1 - 0.026 15.0 7.2 0.031 14.7 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) LETM1 PF07766.13 CDJ50987.1 - 0.064 12.6 3.7 0.075 12.4 3.7 1.1 1 0 0 1 1 1 0 LETM1-like protein Sec10 PF07393.11 CDJ50987.1 - 0.07 11.5 9.7 0.077 11.4 9.7 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Rtf2 PF04641.12 CDJ50987.1 - 0.088 12.2 6.4 0.095 12.0 6.4 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1635 PF07795.11 CDJ50987.1 - 0.21 11.4 11.1 0.24 11.3 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) MID_MedPIWI PF18296.1 CDJ50987.1 - 0.28 11.0 12.1 0.3 10.8 12.1 1.0 1 0 0 1 1 1 0 MID domain of medPIWI Menin PF05053.13 CDJ50987.1 - 0.34 9.2 8.8 0.36 9.1 8.8 1.0 1 0 0 1 1 1 0 Menin Band_3_cyto PF07565.13 CDJ50987.1 - 0.34 10.7 7.6 0.38 10.5 7.6 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CAML PF14963.6 CDJ50987.1 - 0.47 10.5 6.8 0.53 10.4 6.8 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF4692 PF15763.5 CDJ50987.1 - 0.7 10.4 11.8 0.87 10.0 11.8 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Apt1 PF10351.9 CDJ50987.1 - 0.83 8.4 15.9 0.85 8.4 15.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ50987.1 - 0.85 8.3 10.0 0.94 8.2 10.0 1.0 1 0 0 1 1 1 0 Presenilin SCHIP-1 PF10148.9 CDJ50987.1 - 1 8.9 9.4 1.2 8.7 9.4 1.1 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 CCDC106 PF15794.5 CDJ50987.1 - 1.9 8.2 15.2 2.2 8.0 15.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Sec3_C PF09763.9 CDJ50987.1 - 2.5 6.4 12.3 2.7 6.3 12.3 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 SDP_N PF12278.8 CDJ50987.1 - 2.9 8.0 12.2 4 7.6 12.2 1.3 1 0 0 1 1 1 0 Sex determination protein N terminal Macoilin PF09726.9 CDJ50987.1 - 3.3 6.1 16.2 3.4 6.1 16.2 1.1 1 0 0 1 1 1 0 Macoilin family ANAPC_CDC26 PF10471.9 CDJ50987.1 - 3.9 8.4 15.3 13 6.7 15.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 GREB1 PF15782.5 CDJ50987.1 - 4.8 4.2 11.2 5.1 4.1 11.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF515 PF04415.12 CDJ50987.1 - 5.1 5.4 13.6 5.4 5.3 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ANAPC1 PF12859.7 CDJ50987.1 - 5.6 7.5 11.7 6.4 7.4 11.7 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 SSP160 PF06933.11 CDJ50987.1 - 5.9 5.0 17.7 6.8 4.7 17.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SR-25 PF10500.9 CDJ50988.1 - 0.0009 18.9 14.3 0.0009 18.9 14.3 9.3 8 2 2 10 10 10 4 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ50988.1 - 0.0011 17.8 16.6 0.0011 17.8 16.6 5.4 3 2 0 3 3 3 1 Presenilin SR-25 PF10500.9 CDJ50989.1 - 0.0063 16.1 15.7 0.0063 16.1 15.7 5.3 4 1 0 4 4 4 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ50989.1 - 0.0067 16.8 2.7 0.0067 16.8 2.7 11.6 6 3 2 8 8 8 4 Anti-sigma-K factor rskA Secretin_N_2 PF07655.13 CDJ50989.1 - 1.2 9.7 39.7 3.4 8.3 7.9 4.8 4 0 0 4 4 4 0 Secretin N-terminal domain RAP PF08373.10 CDJ50990.1 - 0.00021 21.3 0.0 0.00046 20.2 0.0 1.6 1 0 0 1 1 1 1 RAP domain tRNA_lig_CPD PF08302.11 CDJ50990.1 - 0.021 14.2 8.0 0.3 10.5 0.1 2.3 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain Neuraminidase PF18413.1 CDJ50990.1 - 0.045 13.4 0.7 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 Neuraminidase-like domain DUF2722 PF10846.8 CDJ50990.1 - 0.34 9.8 28.2 0.052 12.5 1.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ50990.1 - 8.1 6.6 54.1 0.28 11.3 6.8 4.6 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ50991.1 - 0.003 17.2 11.6 0.003 17.2 11.6 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ50991.1 - 0.12 12.3 29.9 0.14 12.1 29.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ50991.1 - 4 6.3 8.1 4.3 6.3 8.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Spc7_N PF15402.6 CDJ50991.1 - 6.2 4.9 30.6 7.5 4.7 30.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Adaptin_N PF01602.20 CDJ50993.1 - 4.2e-30 104.8 9.9 1.1e-19 70.4 0.1 4.1 3 1 1 4 4 4 3 Adaptin N terminal region SR-25 PF10500.9 CDJ50993.1 - 1.4e-08 34.6 27.7 2.7e-05 23.9 8.4 3.5 3 1 0 3 3 3 3 Nuclear RNA-splicing-associated protein AP4E_app_platf PF14807.6 CDJ50993.1 - 4.3e-07 30.2 0.0 4.3e-07 30.2 0.0 3.3 3 0 0 3 3 3 1 Adaptin AP4 complex epsilon appendage platform DUF445 PF04286.12 CDJ50993.1 - 1.8 8.3 13.8 0.021 14.6 5.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Neisseria_TspB PF05616.13 CDJ50994.1 - 1.5 7.2 4.0 2.2 6.7 4.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF3138 PF11336.8 CDJ50995.1 - 0.88 8.1 7.0 1.1 7.7 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2057 PF09829.9 CDJ50995.1 - 7.6 6.7 7.2 10 6.2 7.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) SR-25 PF10500.9 CDJ50996.1 - 0.0055 16.4 61.2 0.016 14.9 30.1 3.2 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein Rad54_N PF08658.10 CDJ50996.1 - 0.036 14.2 1.1 0.036 14.2 1.1 3.3 2 1 1 3 3 3 0 Rad54 N terminal Peptidase_M17 PF00883.21 CDJ50997.1 - 9.6e-80 268.2 5.1 3.9e-62 210.3 3.1 2.1 1 1 1 2 2 2 2 Cytosol aminopeptidase family, catalytic domain PA PF02225.22 CDJ50998.1 - 0.0072 16.3 2.1 0.0095 15.9 2.1 1.3 1 0 0 1 1 1 1 PA domain Spt20 PF12090.8 CDJ50998.1 - 0.055 13.1 29.8 0.18 11.4 14.1 2.0 2 0 0 2 2 2 0 Spt20 family DUF2052 PF09747.9 CDJ50998.1 - 0.055 13.6 14.4 0.073 13.2 14.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) BAF1_ABF1 PF04684.13 CDJ50998.1 - 0.18 10.8 13.9 0.24 10.4 13.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4079 PF13301.6 CDJ50998.1 - 0.18 11.9 0.8 0.29 11.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) HA2 PF04408.23 CDJ50998.1 - 0.32 11.3 9.0 0.84 9.9 0.7 2.2 2 0 0 2 2 2 0 Helicase associated domain (HA2) GHMP_kinases_N PF00288.26 CDJ50998.1 - 0.39 11.0 0.1 0.39 11.0 0.1 2.3 2 0 0 2 2 2 0 GHMP kinases N terminal domain RskA PF10099.9 CDJ50998.1 - 0.39 11.0 30.5 22 5.3 30.5 2.2 1 1 0 1 1 1 0 Anti-sigma-K factor rskA ANAPC_CDC26 PF10471.9 CDJ50998.1 - 0.47 11.3 27.7 0.3 11.9 11.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 FTR1 PF03239.14 CDJ50998.1 - 0.53 9.4 5.9 0.63 9.2 5.9 1.0 1 0 0 1 1 1 0 Iron permease FTR1 family Ctf8 PF09696.10 CDJ50998.1 - 0.66 10.3 12.4 0.25 11.7 3.4 2.2 2 0 0 2 2 2 0 Ctf8 YjeF_N PF03853.15 CDJ50998.1 - 0.95 9.3 10.3 0.25 11.2 7.2 1.5 1 1 1 2 2 2 0 YjeF-related protein N-terminus DUF4834 PF16118.5 CDJ50998.1 - 1.2 10.1 17.9 2.9 8.9 6.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 CDJ50998.1 - 2.9 8.9 7.1 8.8 7.3 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PRC2_HTH_1 PF18118.1 CDJ50998.1 - 5.8 7.8 11.3 1.9 9.3 2.3 2.2 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain FAM176 PF14851.6 CDJ50998.1 - 5.8 6.6 11.2 4 7.1 1.9 2.1 2 0 0 2 2 2 0 FAM176 family DUF4698 PF15769.5 CDJ50999.1 - 7.1e-05 22.1 0.0 7.1e-05 22.1 0.0 9.4 8 1 0 9 9 9 1 Domain of unknown function (DUF4698) Shadoo PF14999.6 CDJ51001.1 - 0.011 15.8 1.3 0.015 15.4 1.3 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective SID-1_RNA_chan PF13965.6 CDJ51001.1 - 0.054 11.9 9.7 0.067 11.6 9.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 CDJ51001.1 - 0.1 11.4 39.2 0.12 11.1 39.2 1.0 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 CDJ51001.1 - 0.19 11.8 30.2 0.24 11.5 30.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) VIR_N PF15912.5 CDJ51001.1 - 0.2 11.2 16.9 0.25 10.9 16.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal RR_TM4-6 PF06459.12 CDJ51001.1 - 0.21 11.4 36.7 0.25 11.1 36.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ADP_ribosyl_GH PF03747.14 CDJ51001.1 - 0.52 10.0 6.8 0.71 9.5 6.8 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase PMSI1 PF15322.6 CDJ51001.1 - 0.65 9.4 18.9 0.75 9.2 18.9 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative AUX_IAA PF02309.16 CDJ51001.1 - 0.78 9.5 18.9 0.92 9.3 18.9 1.2 1 0 0 1 1 1 0 AUX/IAA family Endostatin PF06482.11 CDJ51001.1 - 1.4 8.3 25.8 2 7.8 25.8 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CCSAP PF15748.5 CDJ51001.1 - 1.7 8.8 39.8 1.9 8.6 39.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated GAGA_bind PF06217.12 CDJ51001.1 - 2.5 8.3 30.1 3 8.0 30.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MMR1 PF08505.10 CDJ51001.1 - 2.6 8.3 36.2 3.7 7.8 36.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Zip PF02535.22 CDJ51001.1 - 3.2 6.9 21.0 4.3 6.5 21.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter O-antigen_lig PF13425.6 CDJ51001.1 - 3.6 6.3 16.7 4.7 5.9 16.7 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein HemX PF04375.14 CDJ51001.1 - 3.7 6.7 57.7 4.4 6.5 57.7 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SLC12 PF03522.15 CDJ51001.1 - 4.8 6.1 36.2 5.3 6.0 36.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CD20 PF04103.15 CDJ51001.1 - 5.1 7.2 10.3 1.1e+02 2.8 10.3 2.1 1 1 0 1 1 1 0 CD20-like family TCP PF03634.13 CDJ51001.1 - 7.3 7.1 36.2 11 6.6 36.2 1.3 1 0 0 1 1 1 0 TCP family transcription factor PAT1 PF09770.9 CDJ51001.1 - 7.7 4.7 52.8 8 4.6 52.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PA26 PF04636.13 CDJ51001.1 - 8.7 5.1 26.7 9.9 5.0 26.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Baculo_PP31 PF05311.11 CDJ51002.1 - 0.0018 17.8 6.8 0.0047 16.5 6.8 1.6 1 0 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) DUF3602 PF12223.8 CDJ51002.1 - 0.064 13.9 7.6 15 6.3 5.0 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) eIF-3_zeta PF05091.12 CDJ51002.1 - 0.17 10.8 7.6 0.26 10.2 7.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 CDJ51002.1 - 0.18 11.4 23.4 0.5 9.9 23.4 1.8 1 0 0 1 1 1 0 Spt20 family Connexin PF00029.19 CDJ51002.1 - 0.98 9.1 2.4 2.7 7.7 2.4 1.7 1 0 0 1 1 1 0 Connexin DUF4834 PF16118.5 CDJ51002.1 - 4.6 8.3 10.3 34 5.5 10.3 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Rxt3 PF08642.10 CDJ51002.1 - 6.8 7.5 7.1 2 9.2 2.5 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Metallophos PF00149.28 CDJ51004.1 - 0.0011 19.5 0.0 0.0018 18.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SAP130_C PF16014.5 CDJ51005.1 - 0.053 12.6 1.0 0.061 12.4 1.0 1.0 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus PAPA-1 PF04795.12 CDJ51005.1 - 0.12 13.2 0.0 0.16 12.8 0.0 1.2 1 0 0 1 1 1 0 PAPA-1-like conserved region DUF3138 PF11336.8 CDJ51005.1 - 8.4 4.9 14.1 12 4.3 14.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Pkinase PF00069.25 CDJ51006.1 - 1.5e-18 67.1 0.0 1.5e-18 67.1 0.0 2.1 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ51006.1 - 8.5e-08 31.8 1.4 8.5e-08 31.8 1.4 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Spt20 PF12090.8 CDJ51006.1 - 0.0011 18.6 11.5 0.0011 18.6 11.5 3.1 2 1 1 3 3 2 1 Spt20 family ANAPC_CDC26 PF10471.9 CDJ51006.1 - 0.002 18.9 7.9 0.002 18.9 7.9 4.1 2 1 1 3 3 2 1 Anaphase-promoting complex APC subunit CDC26 RskA PF10099.9 CDJ51006.1 - 0.034 14.5 17.8 0.11 12.8 9.2 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA MecA PF05389.12 CDJ51006.1 - 0.12 12.0 7.7 0.076 12.6 0.5 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) eIF-3_zeta PF05091.12 CDJ51006.1 - 0.41 9.6 17.8 0.48 9.3 4.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MPM1 PF17234.2 CDJ51006.1 - 0.61 10.3 16.7 0.23 11.7 0.4 2.6 3 0 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 EOS1 PF12326.8 CDJ51006.1 - 0.74 9.7 5.2 3.5 7.5 0.1 2.2 2 0 0 2 2 2 0 N-glycosylation protein Presenilin PF01080.17 CDJ51006.1 - 1.3 7.7 18.8 1.4 7.6 3.9 2.1 2 0 0 2 2 2 0 Presenilin Suf PF05843.14 CDJ51006.1 - 2.7 7.9 28.6 2.2 8.2 6.4 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) MDM31_MDM32 PF08118.11 CDJ51006.1 - 5.1 5.6 11.2 0.22 10.1 1.5 2.1 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins Peroxin-13_N PF04088.13 CDJ51006.1 - 7.6 6.8 7.4 5.7 7.2 0.8 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DnaJ PF00226.31 CDJ51007.1 - 1.3e-06 28.4 0.0 3.1e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain Glycos_transf_2 PF00535.26 CDJ51008.1 - 2.9e-19 69.5 0.0 7.1e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ51008.1 - 0.018 15.3 0.0 0.018 15.3 0.0 1.6 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Spt20 PF12090.8 CDJ51008.1 - 0.73 9.4 5.2 1.2 8.6 5.2 1.3 1 0 0 1 1 1 0 Spt20 family FSA_C PF10479.9 CDJ51008.1 - 1.8 6.6 4.4 2.9 5.9 4.4 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SR-25 PF10500.9 CDJ51009.1 - 0.0019 17.8 9.1 0.0019 17.8 9.1 5.9 4 2 1 5 5 5 1 Nuclear RNA-splicing-associated protein CAP_GLY PF01302.25 CDJ51010.1 - 1.2e-08 34.8 0.0 1.6e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 CAP-Gly domain NTP_transf_8 PF12281.8 CDJ51010.1 - 0.039 14.0 3.1 0.08 12.9 1.8 1.8 2 0 0 2 2 2 0 Nucleotidyltransferase Shadoo PF14999.6 CDJ51010.1 - 0.081 13.0 18.7 0.56 10.3 3.5 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective E7 PF00527.18 CDJ51010.1 - 0.17 12.1 1.2 0.27 11.4 1.2 1.3 1 0 0 1 1 1 0 E7 protein, Early protein RXLR PF16810.5 CDJ51010.1 - 0.98 9.8 7.9 0.061 13.8 1.1 2.0 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Spt20 PF12090.8 CDJ51010.1 - 2.5 7.6 11.2 3.3 7.3 11.2 1.1 1 0 0 1 1 1 0 Spt20 family Ribosomal_60s PF00428.19 CDJ51010.1 - 8.7 7.0 33.7 4 8.1 11.2 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Orf78 PF06024.12 CDJ51011.1 - 8.4 6.8 14.8 6.5 7.1 0.5 3.2 3 0 0 3 3 3 0 Orf78 (ac78) Myb_DNA-binding PF00249.31 CDJ51012.1 - 0.0011 19.1 0.1 0.0036 17.5 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain MITF_TFEB_C_3_N PF15951.5 CDJ51012.1 - 0.0029 18.2 23.3 0.0029 18.2 23.3 14.0 7 4 6 13 13 13 1 MITF/TFEB/TFEC/TFE3 N-terminus Ribosomal_60s PF00428.19 CDJ51012.1 - 0.014 16.0 10.7 0.014 16.0 10.7 18.7 10 3 5 15 15 15 0 60s Acidic ribosomal protein Cytochrom_C_asm PF01578.20 CDJ51012.1 - 1.2 8.8 3.3 4.6 7.0 3.3 2.0 1 0 0 1 1 1 0 Cytochrome C assembly protein Presenilin PF01080.17 CDJ51014.1 - 0.00012 21.0 48.0 0.0035 16.2 9.7 2.1 2 0 0 2 2 2 2 Presenilin Utp14 PF04615.13 CDJ51014.1 - 0.00076 18.2 33.8 0.0011 17.7 33.8 1.1 1 0 0 1 1 1 1 Utp14 protein FAM60A PF15396.6 CDJ51014.1 - 0.0031 17.6 39.3 0.026 14.5 8.1 2.1 2 0 0 2 2 2 2 Protein Family FAM60A NPR3 PF03666.13 CDJ51014.1 - 0.0083 15.0 42.4 0.08 11.7 25.3 2.0 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIP PF07454.11 CDJ51014.1 - 0.011 15.2 5.2 0.011 15.2 5.2 3.0 2 1 0 2 2 1 0 Stage II sporulation protein P (SpoIIP) Pox_Ag35 PF03286.14 CDJ51014.1 - 0.046 13.5 24.8 0.39 10.5 6.0 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Neur_chan_memb PF02932.16 CDJ51014.1 - 0.053 13.6 38.9 0.4 10.7 7.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2828 PF11443.8 CDJ51014.1 - 0.069 11.2 38.6 0.041 12.0 9.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) CDC45 PF02724.14 CDJ51014.1 - 0.1 10.9 37.8 0.026 12.8 19.1 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF2052 PF09747.9 CDJ51014.1 - 0.14 12.2 51.0 0.28 11.3 26.7 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4366 PF14283.6 CDJ51014.1 - 0.21 11.7 30.5 0.18 11.9 0.7 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4366) BORG_CEP PF14957.6 CDJ51014.1 - 0.31 12.2 30.4 0.82 10.8 15.1 2.3 2 0 0 2 2 2 0 Cdc42 effector Rtf2 PF04641.12 CDJ51014.1 - 0.61 9.4 39.3 1.4 8.2 11.7 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger Humanin PF15040.6 CDJ51014.1 - 0.64 9.5 0.1 0.64 9.5 0.1 2.5 3 0 0 3 3 3 0 Humanin family MCM_bind PF09739.9 CDJ51014.1 - 0.9 7.9 42.8 0.5 8.7 22.1 2.0 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor GPCR_chapero_1 PF11904.8 CDJ51014.1 - 0.9 8.9 28.0 1.1 8.7 3.2 2.1 2 0 0 2 2 2 0 GPCR-chaperone RR_TM4-6 PF06459.12 CDJ51014.1 - 1 9.1 51.5 0.44 10.3 25.2 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3295 PF11702.8 CDJ51014.1 - 1.2 8.4 39.6 2 7.7 12.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) SDA1 PF05285.12 CDJ51014.1 - 1.4 8.3 35.7 0.04 13.4 13.9 2.1 2 0 0 2 2 2 0 SDA1 HCO3_cotransp PF00955.21 CDJ51014.1 - 1.6 7.5 17.3 3.1 6.5 1.0 2.1 2 0 0 2 2 2 0 HCO3- transporter family SID-1_RNA_chan PF13965.6 CDJ51014.1 - 1.7 7.0 21.5 0.86 7.9 8.4 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TT_ORF1 PF02956.14 CDJ51014.1 - 4.2 5.9 26.7 0.19 10.4 2.1 2.2 2 0 0 2 2 2 0 TT viral orf 1 AAA_11 PF13086.6 CDJ51014.1 - 6.9 6.4 44.4 1.6 8.4 11.7 2.1 2 0 0 2 2 2 0 AAA domain Dsh_C PF12316.8 CDJ51014.1 - 8.1 6.8 27.3 1.4 9.3 3.5 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal CAF1 PF04857.20 CDJ51014.1 - 8.2 5.5 31.3 4.3 6.4 15.7 2.3 2 0 0 2 2 2 0 CAF1 family ribonuclease DUF4045 PF13254.6 CDJ51014.1 - 8.6 5.9 42.5 1.7 8.2 19.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Vfa1 PF08432.10 CDJ51014.1 - 9.3 6.5 47.9 0.91 9.8 23.8 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Activator_LAG-3 PF11498.8 CDJ51015.1 - 0.0042 16.1 4.8 0.0042 16.1 4.8 7.0 6 1 1 7 7 7 3 Transcriptional activator LAG-3 CAP_N PF01213.19 CDJ51017.1 - 0.16 11.4 5.5 0.27 10.7 5.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DDHD PF02862.17 CDJ51018.1 - 0.0056 16.9 9.3 0.0067 16.6 9.3 1.2 1 0 0 1 1 1 1 DDHD domain BAF1_ABF1 PF04684.13 CDJ51018.1 - 0.01 14.9 14.3 0.012 14.7 14.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF5427 PF10310.9 CDJ51018.1 - 0.021 13.8 20.2 0.025 13.6 20.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PTPRCAP PF15713.5 CDJ51018.1 - 0.034 14.5 15.7 0.046 14.0 15.7 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Endostatin PF06482.11 CDJ51018.1 - 0.058 12.8 15.9 0.067 12.6 15.9 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4228 PF14009.6 CDJ51018.1 - 0.23 11.8 7.2 0.29 11.5 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Spore_coat_CotO PF14153.6 CDJ51018.1 - 0.27 11.1 25.4 0.35 10.8 25.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Velvet PF11754.8 CDJ51018.1 - 0.68 9.8 20.3 0.86 9.5 20.3 1.1 1 0 0 1 1 1 0 Velvet factor DUF2828 PF11443.8 CDJ51018.1 - 0.75 7.8 17.6 0.9 7.6 17.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CPSF100_C PF13299.6 CDJ51018.1 - 0.94 9.6 15.5 1.5 9.0 15.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4569 PF15133.6 CDJ51018.1 - 1 9.0 19.6 1.3 8.7 19.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) TFIIA PF03153.13 CDJ51018.1 - 1.1 9.2 53.8 1.3 8.9 53.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF913 PF06025.12 CDJ51018.1 - 1.4 7.9 10.9 1.6 7.6 10.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 CDJ51018.1 - 1.7 7.6 21.8 2 7.3 21.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 CDJ51018.1 - 1.7 6.8 16.0 2.1 6.6 16.0 1.0 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.6 CDJ51018.1 - 1.7 6.9 6.7 2 6.8 6.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Connexin PF00029.19 CDJ51018.1 - 1.8 8.3 13.1 2.4 7.9 13.1 1.3 1 0 0 1 1 1 0 Connexin DUF4778 PF16008.5 CDJ51018.1 - 1.8 8.5 17.5 2.3 8.2 17.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Neur_chan_memb PF02932.16 CDJ51018.1 - 1.9 8.5 18.9 2.4 8.2 18.9 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.12 CDJ51018.1 - 2 7.7 16.5 2.5 7.4 16.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Suf PF05843.14 CDJ51018.1 - 2 8.3 27.6 3.4 7.6 27.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SpoIIP PF07454.11 CDJ51018.1 - 2.3 7.6 19.7 3 7.2 19.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Baculo_PP31 PF05311.11 CDJ51018.1 - 2.3 7.6 12.8 3.1 7.2 12.8 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FAM60A PF15396.6 CDJ51018.1 - 2.3 8.2 14.4 3 7.8 14.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A BPL_N PF09825.9 CDJ51018.1 - 2.4 7.2 11.5 3 6.8 11.5 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal PAT1 PF09770.9 CDJ51018.1 - 2.5 6.3 38.6 3 6.0 38.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4050 PF13259.6 CDJ51018.1 - 2.5 8.4 15.5 3.5 7.9 15.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) CCSAP PF15748.5 CDJ51018.1 - 3.3 7.8 24.3 4.2 7.5 24.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ51018.1 - 3.4 7.4 22.8 4.3 7.1 22.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 CDJ51018.1 - 3.5 7.0 13.0 4.7 6.5 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BORG_CEP PF14957.6 CDJ51018.1 - 3.7 8.7 16.1 5 8.3 16.1 1.1 1 0 0 1 1 1 0 Cdc42 effector DUF2464 PF10240.9 CDJ51018.1 - 3.9 7.0 12.4 5.7 6.4 12.4 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 Gti1_Pac2 PF09729.9 CDJ51018.1 - 3.9 7.5 15.4 5.2 7.1 15.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4638 PF15472.6 CDJ51018.1 - 4.6 6.9 14.0 5.9 6.6 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Raftlin PF15250.6 CDJ51018.1 - 4.7 5.8 18.1 5.8 5.5 18.1 1.0 1 0 0 1 1 1 0 Raftlin NARP1 PF12569.8 CDJ51018.1 - 5.5 5.8 17.5 7 5.4 17.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CLN3 PF02487.17 CDJ51018.1 - 5.9 5.8 13.8 7.2 5.5 13.8 1.2 1 0 0 1 1 1 0 CLN3 protein AF-4 PF05110.13 CDJ51018.1 - 6.6 4.7 28.2 8.1 4.4 28.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2126 PF09899.9 CDJ51018.1 - 6.7 4.6 13.4 7.7 4.4 13.4 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Hydin_ADK PF17213.3 CDJ51018.1 - 6.9 6.9 17.7 8.5 6.6 17.7 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Pex14_N PF04695.13 CDJ51018.1 - 7.2 7.2 38.6 10 6.7 38.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CDJ51018.1 - 7.7 5.2 28.2 9.7 4.8 28.2 1.0 1 0 0 1 1 1 0 Presenilin Membralin PF09746.9 CDJ51018.1 - 9.1 5.2 10.8 11 4.9 10.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein eIF-5_eIF-2B PF01873.17 CDJ51019.1 - 8.3e-35 119.2 0.0 1.8e-34 118.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CDJ51019.1 - 7.1e-11 42.1 0.6 7.1e-11 42.1 0.6 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hormone_6 PF00236.18 CDJ51019.1 - 0.08 12.9 0.4 0.16 12.0 0.4 1.4 1 0 0 1 1 1 0 Glycoprotein hormone TFIIF_alpha PF05793.12 CDJ51019.1 - 0.15 10.6 40.8 0.26 9.8 40.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GREB1 PF15782.5 CDJ51019.1 - 0.43 7.6 9.1 0.56 7.3 9.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDJ51019.1 - 0.77 8.3 17.1 1 7.9 17.1 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 CDJ51019.1 - 0.91 9.0 14.5 1.3 8.5 14.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ51019.1 - 1.5 7.5 14.8 2.4 6.9 14.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop14 PF04147.12 CDJ51019.1 - 8.6 4.4 31.2 12 4.0 31.2 1.1 1 0 0 1 1 1 0 Nop14-like family Metallophos_2 PF12850.7 CDJ51020.1 - 1.7e-14 54.4 0.1 2e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CDJ51020.1 - 0.00024 21.7 2.1 0.0088 16.6 0.6 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase CHCH PF06747.13 CDJ51021.1 - 1.3e-05 25.2 2.8 2.3e-05 24.4 2.6 1.6 1 1 1 2 2 2 2 CHCH domain CX9C PF16860.5 CDJ51021.1 - 0.75 9.9 6.4 0.15 12.1 1.4 2.0 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pex14_N PF04695.13 CDJ51022.1 - 0.0079 16.9 11.3 0.0079 16.9 11.3 1.5 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ51022.1 - 0.054 13.1 7.1 0.073 12.7 7.1 1.1 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ51022.1 - 6.1 5.8 7.5 8.3 5.4 7.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Ribosomal_L7Ae PF01248.26 CDJ51023.1 - 1.2e-22 79.5 2.0 2.2e-22 78.6 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CDJ51023.1 - 0.031 14.3 0.1 0.061 13.4 0.1 1.5 1 0 0 1 1 1 0 RNase P subunit Pop3 tRNA-synt_His PF13393.6 CDJ51024.1 - 9.5e-15 54.7 0.2 9.8e-08 31.6 0.1 3.2 3 0 0 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CDJ51024.1 - 0.085 13.0 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Anticodon binding domain Cyclin PF08613.11 CDJ51026.1 - 1e-06 29.2 0.0 2.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Cyclin SMP_2 PF10144.9 CDJ51026.1 - 0.0055 16.4 0.1 0.57 9.8 0.0 2.2 2 0 0 2 2 2 2 Bacterial virulence factor haemolysin Cyclin_N PF00134.23 CDJ51026.1 - 0.014 15.2 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 Cyclin, N-terminal domain Suf PF05843.14 CDJ51027.1 - 0.068 13.2 16.3 0.088 12.8 16.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM60A PF15396.6 CDJ51027.1 - 0.1 12.6 5.1 0.13 12.2 5.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.9 CDJ51027.1 - 0.21 9.8 21.6 0.23 9.7 21.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ51027.1 - 0.22 10.2 12.4 0.27 9.9 12.4 1.1 1 0 0 1 1 1 0 Presenilin Neuraminidase PF18413.1 CDJ51027.1 - 0.3 10.7 6.6 0.4 10.3 6.6 1.3 1 0 0 1 1 1 0 Neuraminidase-like domain Bul1_N PF04425.12 CDJ51027.1 - 0.71 8.6 9.6 0.97 8.1 9.6 1.2 1 0 0 1 1 1 0 Bul1 N terminus DUF2489 PF10675.9 CDJ51027.1 - 0.79 9.6 21.4 0.037 14.0 9.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) ALMT PF11744.8 CDJ51027.1 - 1.2 7.9 7.4 1.5 7.6 7.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 CDJ51027.1 - 2.9 7.7 11.6 3.7 7.3 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ51027.1 - 5.1 7.1 11.0 6.9 6.7 11.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 CDJ51029.1 - 0.37 9.5 19.5 0.46 9.2 19.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF966 PF06136.13 CDJ51029.1 - 1.2 8.8 23.2 1.5 8.5 23.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) VIR_N PF15912.5 CDJ51029.1 - 5.4 6.5 21.9 8.9 5.8 21.9 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal S6PP PF05116.13 CDJ51030.1 - 8.4e-08 32.0 4.8 1.4e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase DUF3446 PF11928.8 CDJ51030.1 - 0.00071 19.8 1.4 0.0017 18.7 1.4 1.5 1 0 0 1 1 1 1 Early growth response N-terminal domain CBM53 PF16760.5 CDJ51030.1 - 0.0061 17.1 0.1 0.013 16.1 0.1 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) EIIBC-GUT_N PF03612.14 CDJ51030.1 - 0.47 10.2 7.4 0.7 9.6 2.4 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Trypan_PARP PF05887.11 CDJ51030.1 - 0.64 10.0 6.8 1.1 9.2 6.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Vfa1 PF08432.10 CDJ51030.1 - 0.8 10.0 20.7 0.049 14.0 9.8 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF1645 PF07816.11 CDJ51030.1 - 1.1 9.8 16.7 15 6.1 14.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1645) Connexin PF00029.19 CDJ51030.1 - 1.6 8.4 10.7 1 9.1 4.8 2.1 2 0 0 2 2 2 0 Connexin DUF3408 PF11888.8 CDJ51030.1 - 1.9 8.7 16.3 2.2 8.4 9.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Peptidase_S49_N PF08496.10 CDJ51030.1 - 2 8.4 17.7 3.3 7.8 7.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Gti1_Pac2 PF09729.9 CDJ51030.1 - 2.2 8.4 14.9 0.46 10.6 7.3 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family DDHD PF02862.17 CDJ51030.1 - 3 7.9 16.7 0.78 9.9 0.7 2.5 2 1 0 2 2 2 0 DDHD domain DUF3915 PF13054.6 CDJ51030.1 - 3.2 7.7 12.1 6.8 6.7 11.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) SpoIIP PF07454.11 CDJ51030.1 - 3.8 6.9 15.6 0.5 9.8 6.9 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF1168 PF06658.12 CDJ51030.1 - 3.8 7.3 25.4 0.71 9.7 10.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Eapp_C PF10238.9 CDJ51030.1 - 4.7 7.3 12.7 1 9.5 4.7 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Cytomega_UL84 PF06284.11 CDJ51030.1 - 5 5.5 6.6 8.1 4.8 6.6 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Apt1 PF10351.9 CDJ51030.1 - 5 5.9 17.0 0.016 14.1 4.4 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain FAM176 PF14851.6 CDJ51030.1 - 5.7 6.6 9.9 5.2 6.7 5.6 2.2 2 0 0 2 2 2 0 FAM176 family DUF4770 PF15994.5 CDJ51030.1 - 5.7 7.1 15.7 9.3 6.5 4.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF1764 PF08576.10 CDJ51030.1 - 9 7.3 18.7 0.53 11.2 7.6 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) PTS_2-RNA PF01885.16 CDJ51031.1 - 9.8e-17 61.6 0.0 3.6e-11 43.4 0.0 2.9 3 0 0 3 3 3 2 RNA 2'-phosphotransferase, Tpt1 / KptA family SDA1 PF05285.12 CDJ51031.1 - 0.34 10.3 31.7 4.3 6.7 30.2 2.3 2 0 0 2 2 2 0 SDA1 Nop53 PF07767.11 CDJ51031.1 - 0.97 8.8 42.3 2.9 7.2 42.3 1.8 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Spt20 PF12090.8 CDJ51032.1 - 0.00024 20.8 10.7 0.00027 20.6 10.7 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ51032.1 - 0.064 12.2 11.5 0.07 12.1 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ51032.1 - 0.074 13.7 10.1 0.091 13.4 10.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ51032.1 - 0.1 12.6 16.1 0.12 12.3 16.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ51032.1 - 0.33 9.2 7.9 0.34 9.1 7.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.8 CDJ51032.1 - 1.2 8.0 21.1 1.5 7.7 21.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Tic110 PF16940.5 CDJ51032.1 - 3.7 5.9 5.4 3.9 5.8 5.4 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Protamine_P2 PF00841.19 CDJ51032.1 - 4 8.0 8.7 6.2 7.4 8.7 1.3 1 0 0 1 1 1 0 Sperm histone P2 Roughex PF06020.11 CDJ51032.1 - 4.3 6.3 11.3 4.9 6.1 11.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 CDJ51032.1 - 6.6 5.4 5.0 7.6 5.2 5.0 1.1 1 0 0 1 1 1 0 Presenilin TPMT PF05724.11 CDJ51033.1 - 0.017 14.8 0.0 0.018 14.7 0.0 1.0 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF1645 PF07816.11 CDJ51034.1 - 0.002 18.8 25.7 0.003 18.2 25.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) PAT1 PF09770.9 CDJ51034.1 - 0.024 12.9 36.3 0.025 12.9 36.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3801 PF12687.7 CDJ51034.1 - 0.14 12.3 28.4 0.22 11.6 28.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Miga PF10265.9 CDJ51034.1 - 0.26 10.2 21.9 0.33 9.9 21.9 1.1 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 CDJ51034.1 - 0.27 9.7 27.3 0.41 9.2 27.3 1.3 1 0 0 1 1 1 0 Macoilin family LMBR1 PF04791.16 CDJ51034.1 - 1.8 7.3 7.0 2.6 6.8 7.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SPX PF03105.19 CDJ51034.1 - 2.1 8.2 31.0 2.7 7.8 31.0 1.1 1 0 0 1 1 1 0 SPX domain AAA_23 PF13476.6 CDJ51034.1 - 3.6 8.0 21.5 2.4 8.6 14.0 2.1 2 0 0 2 2 2 0 AAA domain Mem_trans PF03547.18 CDJ51034.1 - 6.4 5.1 13.1 8.8 4.6 13.1 1.2 1 0 0 1 1 1 0 Membrane transport protein SARAF PF06682.12 CDJ51035.1 - 0.0042 16.8 3.8 0.0042 16.8 3.8 7.5 4 3 2 6 6 6 3 SOCE-associated regulatory factor of calcium homoeostasis Helicase_C PF00271.31 CDJ51035.1 - 0.35 11.2 0.0 0.35 11.2 0.0 5.0 5 1 0 5 5 5 0 Helicase conserved C-terminal domain Thymidylat_synt PF00303.19 CDJ51036.1 - 3.1e-104 347.8 0.0 5.3e-104 347.1 0.0 1.4 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 CDJ51036.1 - 5.4e-29 101.0 0.0 9.3e-10 38.4 0.0 3.8 2 1 1 3 3 3 3 Dihydrofolate reductase TCP PF03634.13 CDJ51036.1 - 0.099 13.2 26.1 0.21 12.1 4.7 2.5 2 0 0 2 2 2 0 TCP family transcription factor AAA_11 PF13086.6 CDJ51036.1 - 0.21 11.4 23.7 0.14 11.9 4.6 2.2 2 0 0 2 2 2 0 AAA domain SLC12 PF03522.15 CDJ51036.1 - 0.51 9.3 28.5 1.2 8.0 8.7 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Presenilin PF01080.17 CDJ51036.1 - 0.84 8.3 38.0 0.77 8.5 9.1 2.2 2 0 0 2 2 2 0 Presenilin Pex14_N PF04695.13 CDJ51038.1 - 0.47 11.1 42.4 0.68 10.6 42.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SelP_N PF04592.14 CDJ51038.1 - 1.8 7.9 33.6 2.4 7.5 33.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3678 PF12435.8 CDJ51038.1 - 5.5 6.4 7.2 10 5.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) eIF3_subunit PF08597.10 CDJ51039.1 - 3.2e-05 24.0 11.8 3.4e-05 23.9 11.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Coilin_N PF15862.5 CDJ51039.1 - 0.083 12.7 7.7 0.095 12.5 7.7 1.1 1 0 0 1 1 1 0 Coilin N-terminus Spt20 PF12090.8 CDJ51039.1 - 0.12 12.0 18.5 0.12 12.0 18.5 1.1 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ51039.1 - 0.16 12.0 9.0 0.17 11.9 9.0 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 CDJ51039.1 - 0.18 12.4 11.0 0.19 12.3 11.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 CDJ51039.1 - 1.1 8.2 20.3 1.2 8.0 20.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF808 PF05661.12 CDJ51039.1 - 1.4 7.8 3.3 1.8 7.5 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF808) DUF3464 PF11947.8 CDJ51039.1 - 1.5 8.5 8.2 1.6 8.4 8.2 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Ctr PF04145.15 CDJ51039.1 - 1.6 9.3 2.8 1.6 9.4 2.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Presenilin PF01080.17 CDJ51039.1 - 1.7 7.3 6.3 1.6 7.4 6.3 1.0 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ51039.1 - 1.7 7.2 5.8 1.8 7.2 5.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4834 PF16118.5 CDJ51039.1 - 2 9.5 8.6 2.3 9.3 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 CDJ51039.1 - 5.4 5.7 15.7 5.4 5.7 15.7 1.1 1 0 0 1 1 1 0 Androgen receptor RskA PF10099.9 CDJ51041.1 - 0.003 17.9 16.5 0.0044 17.4 16.5 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF3464 PF11947.8 CDJ51041.1 - 0.0082 15.9 0.8 0.0082 15.9 0.8 2.0 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 Connexin PF00029.19 CDJ51041.1 - 7.7 6.2 8.7 2.2 8.0 5.2 1.7 2 0 0 2 2 2 0 Connexin PPDK_N PF01326.19 CDJ51042.1 - 2.6e-09 36.8 11.6 3e-08 33.3 11.6 2.5 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain HC2 PF07382.11 CDJ51042.1 - 6.4e-09 36.2 34.4 6.4e-09 36.2 34.4 2.6 3 0 0 3 3 3 1 Histone H1-like nucleoprotein HC2 IMUP PF15761.5 CDJ51042.1 - 0.015 16.0 6.9 0.015 16.0 6.9 6.7 4 2 2 6 6 6 0 Immortalisation up-regulated protein Cupin_8 PF13621.6 CDJ51043.1 - 0.11 12.2 3.8 0.18 11.5 3.3 1.7 1 1 0 1 1 1 0 Cupin-like domain DUF726 PF05277.12 CDJ51043.1 - 0.5 9.2 2.4 0.81 8.6 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) RXT2_N PF08595.11 CDJ51044.1 - 1.8 8.5 24.3 0.74 9.8 10.8 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal ESM4 PF15952.5 CDJ51044.1 - 2.2 8.7 36.4 1.1 9.7 6.8 2.4 2 0 0 2 2 2 0 Enhancer of split M4 family Utp14 PF04615.13 CDJ51044.1 - 4.3 5.8 55.2 4.9 5.6 55.2 1.0 1 0 0 1 1 1 0 Utp14 protein eIF-3_zeta PF05091.12 CDJ51044.1 - 5.9 5.8 38.7 0.18 10.8 5.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Mito_carr PF00153.27 CDJ51045.1 - 6.8e-15 54.8 0.8 1.7e-10 40.7 0.3 3.6 4 1 0 4 4 4 2 Mitochondrial carrier protein SR-25 PF10500.9 CDJ51045.1 - 0.00064 19.4 36.4 0.0015 18.2 10.6 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 CDJ51045.1 - 0.014 15.3 10.1 0.014 15.3 10.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) TFIIA PF03153.13 CDJ51045.1 - 0.018 15.1 24.3 0.028 14.4 24.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4667 PF15700.5 CDJ51045.1 - 0.22 11.6 22.0 1.3 9.1 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ51045.1 - 2.8 7.8 16.7 2.1 8.2 1.4 2.0 2 0 0 2 2 2 0 SPX domain Apt1 PF10351.9 CDJ51045.1 - 4.2 6.1 15.4 1.4 7.6 5.2 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain Spt20 PF12090.8 CDJ51046.1 - 0.026 14.1 36.9 0.033 13.8 9.6 2.2 2 0 0 2 2 2 0 Spt20 family Peptidase_S49_N PF08496.10 CDJ51046.1 - 0.24 11.4 13.1 0.26 11.4 3.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4834 PF16118.5 CDJ51046.1 - 0.32 12.0 14.9 1.9 9.5 3.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MAT1 PF06391.13 CDJ51046.1 - 0.32 10.8 18.5 0.6 9.9 6.9 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Phage_Gp15 PF06854.11 CDJ51046.1 - 0.47 10.4 9.7 2.5 8.1 2.1 2.2 2 0 0 2 2 2 0 Bacteriophage Gp15 protein Activator_LAG-3 PF11498.8 CDJ51046.1 - 0.55 9.2 43.4 1.2 8.0 20.3 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 RteC PF09357.10 CDJ51046.1 - 0.63 9.7 7.0 0.37 10.4 0.5 2.2 2 0 0 2 2 2 0 RteC protein CDH1_2_SANT_HL1 PF18375.1 CDJ51046.1 - 1.1 10.0 7.3 7.8 7.3 0.6 2.3 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 RasGEF_N PF00618.20 CDJ51046.1 - 2.2 8.5 4.6 2.8 8.2 0.4 2.2 2 0 0 2 2 2 0 RasGEF N-terminal motif DFRP_C PF16543.5 CDJ51046.1 - 2.6 8.6 7.5 3.7 8.1 0.4 2.5 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 PRC2_HTH_1 PF18118.1 CDJ51046.1 - 3.4 8.5 10.1 16 6.4 3.5 2.4 2 1 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain DUF1455 PF07306.11 CDJ51046.1 - 4.4 7.3 11.7 7.3 6.6 11.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) Jak1_Phl PF17887.1 CDJ51046.1 - 4.8 7.2 12.5 3.2 7.7 3.7 2.2 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain DDE_1 PF03184.19 CDJ51046.1 - 6.3 6.4 11.7 2.6 7.7 0.7 2.4 2 1 0 2 2 2 0 DDE superfamily endonuclease CNDH2_N PF06278.11 CDJ51046.1 - 7 6.9 16.1 3.7 7.8 3.4 2.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Renin_r PF07850.14 CDJ51046.1 - 7.3 7.3 9.6 13 6.5 1.2 2.4 2 0 0 2 2 2 0 Renin receptor-like protein DUF4813 PF16072.5 CDJ51046.1 - 8.6 5.9 30.8 11 5.5 30.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) RskA PF10099.9 CDJ51047.1 - 0.87 9.9 23.8 2.6 8.3 23.8 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ51048.1 - 0.0031 17.8 4.5 0.0031 17.8 4.5 5.6 3 1 1 4 4 4 1 Anti-sigma-K factor rskA DUF2205 PF10224.9 CDJ51048.1 - 0.0098 15.9 1.5 0.0098 15.9 1.5 3.0 3 0 0 3 3 3 1 Short coiled-coil protein WD40 PF00400.32 CDJ51050.1 - 0.003 18.4 1.2 29 5.7 0.0 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat RNA_pol_Rpb4 PF03874.16 CDJ51051.1 - 0.00011 22.5 0.2 0.00037 20.8 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase Rpb4 FXR_C1 PF16096.5 CDJ51051.1 - 0.28 11.4 5.2 0.87 9.8 5.2 1.8 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 DER1 PF04511.15 CDJ51052.1 - 2e-43 148.6 14.8 2.3e-43 148.4 14.8 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 CDJ51052.1 - 3.3e-06 27.2 15.5 5.2e-06 26.5 15.5 1.3 1 0 0 1 1 1 1 Rhomboid family RskA PF10099.9 CDJ51053.1 - 0.00084 19.7 1.2 0.00084 19.7 1.2 2.1 2 0 0 2 2 2 1 Anti-sigma-K factor rskA RAB3GAP2_N PF14655.6 CDJ51053.1 - 0.0073 15.6 0.4 0.015 14.6 0.4 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus OTT_1508_deam PF14441.6 CDJ51053.1 - 0.1 12.6 0.3 0.25 11.4 0.3 1.6 1 0 0 1 1 1 0 OTT_1508-like deaminase K_channel_TID PF07941.11 CDJ51053.1 - 0.25 11.8 28.0 0.044 14.2 11.7 3.6 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain DNA_pol_A PF00476.20 CDJ51054.1 - 3.6e-15 55.9 0.3 3.6e-15 55.9 0.3 2.4 3 1 0 3 3 3 1 DNA polymerase family A SR-25 PF10500.9 CDJ51054.1 - 0.0023 17.6 10.3 0.0023 17.6 10.3 7.4 6 2 1 7 7 7 3 Nuclear RNA-splicing-associated protein DNA_pol_A PF00476.20 CDJ51055.1 - 2e-15 56.8 13.2 2.5e-13 49.8 0.1 3.3 3 0 0 3 3 3 2 DNA polymerase family A 5_3_exonuc PF01367.20 CDJ51055.1 - 9.2e-11 42.2 0.0 9.2e-11 42.2 0.0 2.7 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 CDJ51055.1 - 0.00024 21.0 0.0 0.86 9.5 0.0 2.6 2 0 0 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain Sin_N PF04801.13 CDJ51055.1 - 0.15 11.3 0.0 0.15 11.3 0.0 7.2 7 1 0 7 7 7 0 Sin-like protein conserved region Spt20 PF12090.8 CDJ51056.1 - 0.019 14.6 44.8 0.21 11.2 24.9 2.1 2 0 0 2 2 2 0 Spt20 family DUF755 PF05501.11 CDJ51056.1 - 0.029 14.6 27.4 0.029 14.6 27.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) AF-4 PF05110.13 CDJ51056.1 - 1.3 7.0 33.2 1.6 6.7 33.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Exo_endo_phos PF03372.23 CDJ51057.1 - 3.4e-05 23.5 0.0 0.0029 17.2 0.0 2.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Presenilin PF01080.17 CDJ51057.1 - 0.0015 17.4 0.2 0.0015 17.4 0.2 4.9 3 1 0 3 3 3 2 Presenilin Med3 PF11593.8 CDJ51057.1 - 0.0044 16.3 27.5 0.0044 16.3 27.5 4.3 4 1 0 4 4 4 1 Mediator complex subunit 3 fungal Allene_ox_cyc PF06351.11 CDJ51057.1 - 0.073 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Allene oxide cyclase Ribosomal_60s PF00428.19 CDJ51058.1 - 2.3 8.9 8.2 8.9 7.0 8.2 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3446 PF11928.8 CDJ51060.1 - 9.9 6.5 13.4 60 4.0 13.4 2.4 1 0 0 1 1 1 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ51061.1 - 5.7e-05 22.8 26.4 9e-05 22.2 26.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ51061.1 - 0.052 13.7 31.3 0.063 13.4 31.3 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4603 PF15376.6 CDJ51061.1 - 0.3 8.4 20.0 0.34 8.3 20.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Spc7_N PF15402.6 CDJ51061.1 - 0.36 9.0 25.1 0.43 8.8 25.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Pal1 PF08316.11 CDJ51061.1 - 0.75 10.6 14.8 0.92 10.3 14.8 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein TFIIA PF03153.13 CDJ51061.1 - 1 9.3 34.9 1.2 9.1 34.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2052 PF09747.9 CDJ51061.1 - 1.1 9.3 29.3 1.3 9.1 29.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Paf1 PF03985.13 CDJ51061.1 - 2.4 7.1 34.6 3.1 6.7 34.6 1.2 1 0 0 1 1 1 0 Paf1 DUF5427 PF10310.9 CDJ51061.1 - 2.6 6.9 30.2 3.1 6.7 30.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Dsh_C PF12316.8 CDJ51061.1 - 2.7 8.4 28.3 3.1 8.1 28.3 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Merozoite_SPAM PF07133.11 CDJ51061.1 - 3.5 7.6 30.0 4.3 7.3 30.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PTPRCAP PF15713.5 CDJ51061.1 - 3.5 7.9 32.5 4.4 7.6 32.5 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Mpp10 PF04006.12 CDJ51061.1 - 3.9 5.8 32.0 4.4 5.6 32.0 1.0 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.12 CDJ51061.1 - 4 7.2 31.9 4.9 6.9 31.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TRAP_alpha PF03896.16 CDJ51061.1 - 6 6.0 15.7 7 5.8 15.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Endostatin PF06482.11 CDJ51061.1 - 6.8 6.1 19.6 7.8 5.9 19.6 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin STAC2_u1 PF16664.5 CDJ51061.1 - 8.2 6.9 28.8 10 6.6 28.8 1.1 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Totivirus_coat PF05518.11 CDJ51061.1 - 8.3 4.3 10.6 9 4.2 10.6 1.0 1 0 0 1 1 1 0 Totivirus coat protein SOBP PF15279.6 CDJ51061.1 - 8.9 6.8 20.6 9.4 6.7 20.6 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein TCP PF03634.13 CDJ51061.1 - 9.7 6.7 31.6 11 6.6 31.6 1.0 1 0 0 1 1 1 0 TCP family transcription factor Spem1 PF15670.5 CDJ51061.1 - 9.7 5.7 17.6 13 5.3 17.6 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Activator_LAG-3 PF11498.8 CDJ51061.1 - 9.7 5.0 43.3 11 4.8 43.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FAM60A PF15396.6 CDJ51062.1 - 0.27 11.2 28.6 0.3 11.1 28.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SMYLE_N PF18615.1 CDJ51062.1 - 0.78 9.2 23.8 1.1 8.8 23.8 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Presenilin PF01080.17 CDJ51062.1 - 1.4 7.6 44.6 1.6 7.4 44.6 1.0 1 0 0 1 1 1 0 Presenilin XRN_M PF17846.1 CDJ51062.1 - 3 6.7 32.0 3.5 6.5 32.0 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DUF4045 PF13254.6 CDJ51062.1 - 5.8 6.5 31.5 7.1 6.2 31.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SLC12 PF03522.15 CDJ51062.1 - 6.4 5.7 39.5 7.7 5.4 39.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF1387 PF07139.11 CDJ51062.1 - 9.4 5.9 33.6 13 5.4 33.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) LRR_6 PF13516.6 CDJ51063.1 - 0.019 15.0 2.1 27 5.1 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat SUIM_assoc PF16619.5 CDJ51063.1 - 6.2 7.0 16.0 21 5.3 16.0 1.9 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ51064.1 - 0.001 19.4 10.8 0.001 19.4 10.8 4.1 1 1 1 3 3 3 1 Anti-sigma-K factor rskA SRP54 PF00448.22 CDJ51065.1 - 6.5e-48 163.0 0.2 1.1e-47 162.3 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CDJ51065.1 - 3.2e-28 98.3 1.0 1.3e-27 96.3 0.2 2.2 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 CDJ51065.1 - 3.8e-12 46.3 0.1 9.6e-12 45.0 0.1 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain DRE2_N PF16803.5 CDJ51065.1 - 0.017 15.4 0.0 5.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus DUF2209 PF09974.9 CDJ51065.1 - 0.021 15.1 0.2 0.06 13.7 0.2 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Methyltransf_24 PF13578.6 CDJ51065.1 - 0.14 13.2 0.2 0.31 12.1 0.2 1.7 1 0 0 1 1 1 0 Methyltransferase domain SR-25 PF10500.9 CDJ51065.1 - 0.31 10.6 8.2 0.066 12.8 4.6 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CDK2AP PF09806.9 CDJ51065.1 - 3.6 7.6 8.0 7.3 6.6 8.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Suf PF05843.14 CDJ51066.1 - 0.00019 21.5 4.2 0.00021 21.4 4.2 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Pex14_N PF04695.13 CDJ51066.1 - 0.0013 19.4 12.1 0.0013 19.4 12.1 2.9 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ51066.1 - 0.0014 18.5 0.3 0.25 11.1 5.8 1.8 2 0 0 2 2 2 1 Connexin RskA PF10099.9 CDJ51066.1 - 0.0015 18.9 12.0 0.0015 18.9 12.0 4.1 1 1 1 3 3 1 1 Anti-sigma-K factor rskA Trypan_glycop_C PF10659.9 CDJ51066.1 - 0.0077 16.6 6.4 0.0077 16.6 6.4 2.4 2 1 0 2 2 1 1 Trypanosome variant surface glycoprotein C-terminal domain eIF-3_zeta PF05091.12 CDJ51066.1 - 0.01 14.9 14.0 0.013 14.5 14.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ51066.1 - 0.017 15.2 3.2 0.021 14.9 3.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cryptochrome_C PF12546.8 CDJ51066.1 - 0.021 15.4 11.9 0.034 14.7 11.9 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Spt20 PF12090.8 CDJ51066.1 - 0.023 14.3 34.1 0.063 12.9 34.1 1.7 1 0 0 1 1 1 0 Spt20 family EOS1 PF12326.8 CDJ51066.1 - 0.033 14.1 0.5 0.039 13.9 0.5 1.4 1 0 0 1 1 1 0 N-glycosylation protein DUF702 PF05142.12 CDJ51066.1 - 0.046 14.2 11.2 0.081 13.4 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF3408 PF11888.8 CDJ51066.1 - 0.064 13.4 8.1 0.12 12.5 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) EIIBC-GUT_N PF03612.14 CDJ51066.1 - 0.074 12.8 10.1 0.18 11.5 10.1 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CLN3 PF02487.17 CDJ51066.1 - 0.09 11.8 4.1 8.3 5.3 8.9 1.7 2 0 0 2 2 2 0 CLN3 protein SID-1_RNA_chan PF13965.6 CDJ51066.1 - 0.17 10.3 2.0 1.6 7.0 2.7 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Ctr PF04145.15 CDJ51066.1 - 0.21 12.2 5.9 1.6 9.3 4.8 2.3 2 1 0 2 2 2 0 Ctr copper transporter family PEHE PF15275.6 CDJ51066.1 - 0.26 11.9 11.8 0.47 11.1 11.8 1.3 1 0 0 1 1 1 0 PEHE domain DUF2828 PF11443.8 CDJ51066.1 - 0.29 9.2 9.7 0.43 8.6 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TERB2 PF15101.6 CDJ51066.1 - 0.31 11.0 16.0 0.51 10.4 16.0 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NeuB PF03102.14 CDJ51066.1 - 0.44 10.0 6.1 0.66 9.4 6.1 1.2 1 0 0 1 1 1 0 NeuB family DUF4770 PF15994.5 CDJ51066.1 - 0.51 10.6 12.4 0.76 10.0 12.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) V_ATPase_I PF01496.19 CDJ51066.1 - 0.58 8.0 13.2 21 2.8 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family ASC PF00858.24 CDJ51066.1 - 0.88 8.5 10.1 1.3 7.9 10.1 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel MMU163 PF17119.5 CDJ51066.1 - 0.9 8.6 6.5 2 7.5 6.5 1.5 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF2367 PF10164.9 CDJ51066.1 - 1.1 9.9 4.0 2.1 8.9 4.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Peptidase_S49_N PF08496.10 CDJ51066.1 - 1.1 9.3 7.9 1.9 8.6 7.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LMBR1 PF04791.16 CDJ51066.1 - 1.2 8.0 5.2 1.7 7.4 5.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MAS20 PF02064.15 CDJ51066.1 - 2.1 8.4 14.0 5.2 7.2 14.0 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor Ureide_permease PF07168.11 CDJ51066.1 - 2.6 6.7 4.4 5.3 5.7 4.4 1.5 1 0 0 1 1 1 0 Ureide permease CSG2 PF16965.5 CDJ51066.1 - 3.1 6.7 6.0 5.3 5.9 6.0 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator Band_3_cyto PF07565.13 CDJ51066.1 - 3.3 7.4 11.8 4.9 6.9 11.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain OATP PF03137.20 CDJ51066.1 - 3.3 5.9 6.2 5.7 5.1 6.2 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MMR1 PF08505.10 CDJ51066.1 - 4.7 7.4 19.3 6.6 6.9 19.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein G0-G1_switch_2 PF15103.6 CDJ51066.1 - 5.2 7.5 9.5 12 6.4 9.5 1.6 1 0 0 1 1 1 0 G0/G1 switch protein 2 Thioredoxin PF00085.20 CDJ51068.1 - 4.9e-43 145.3 4.2 5e-23 81.0 0.1 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CDJ51068.1 - 4.6e-21 75.6 4.8 9.1e-18 64.8 0.1 3.3 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ51068.1 - 9.3e-09 35.5 0.0 0.026 14.9 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 CDJ51068.1 - 2.5e-08 34.0 3.2 0.0054 16.9 0.0 3.6 3 1 1 4 4 3 2 Thioredoxin-like OST3_OST6 PF04756.13 CDJ51068.1 - 7.9e-08 32.0 1.7 0.0022 17.4 0.1 3.3 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CDJ51068.1 - 3.1e-07 30.8 3.2 0.0058 17.1 0.2 3.7 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 CDJ51068.1 - 7.4e-06 25.9 0.4 0.041 13.8 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 CDJ51068.1 - 7.8e-06 25.7 1.4 0.035 13.8 0.1 2.9 2 1 0 2 2 2 2 Redoxin Calsequestrin PF01216.17 CDJ51068.1 - 0.0002 20.5 0.4 0.0028 16.8 0.4 2.4 2 0 0 2 2 2 1 Calsequestrin TraF PF13728.6 CDJ51068.1 - 0.00022 21.1 0.4 0.033 14.0 0.0 3.1 2 2 1 3 3 3 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CDJ51068.1 - 0.0017 18.1 0.1 0.38 10.5 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin DUF2016 PF09436.10 CDJ51068.1 - 0.093 12.6 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) CAT PF00302.18 CDJ51068.1 - 0.099 12.6 0.8 0.29 11.1 0.2 2.0 2 0 0 2 2 2 0 Chloramphenicol acetyltransferase ERp29_N PF07912.13 CDJ51068.1 - 0.13 12.4 0.0 5 7.3 0.0 2.8 3 0 0 3 3 3 0 ERp29, N-terminal domain Cys_knot PF00007.22 CDJ51068.1 - 0.16 12.3 0.0 19 5.6 0.0 2.3 2 0 0 2 2 2 0 Cystine-knot domain Thioredoxin_3 PF13192.6 CDJ51068.1 - 0.23 11.5 1.0 4.7 7.3 0.0 3.4 4 0 0 4 4 3 0 Thioredoxin domain Glutaredoxin PF00462.24 CDJ51068.1 - 3.1 8.1 7.2 14 6.0 0.3 3.7 2 2 0 2 2 2 0 Glutaredoxin Peptidase_M24 PF00557.24 CDJ51068.1 - 8 6.1 11.4 7 6.3 7.4 2.4 2 1 1 3 3 3 0 Metallopeptidase family M24 Spt20 PF12090.8 CDJ51069.1 - 4.6 6.8 13.9 6.3 6.3 13.9 1.1 1 0 0 1 1 1 0 Spt20 family DLIC PF05783.11 CDJ51069.1 - 6.9 5.4 12.6 8.8 5.0 12.6 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Ribosomal_60s PF00428.19 CDJ51070.1 - 0.018 15.6 7.2 0.018 15.6 7.2 5.4 5 2 2 7 7 7 0 60s Acidic ribosomal protein Latrophilin PF02354.16 CDJ51070.1 - 0.3 10.1 6.6 0.046 12.8 2.6 1.6 2 0 0 2 2 2 0 Latrophilin Cytoplasmic C-terminal region Gp_dh_C PF02800.20 CDJ51071.1 - 1.4e-67 226.2 0.0 1.9e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CDJ51071.1 - 9.5e-23 80.5 0.0 2.3e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TMEM154 PF15102.6 CDJ51072.1 - 0.061 13.2 0.0 0.061 13.2 0.0 3.7 3 1 1 4 4 4 0 TMEM154 protein family Peptidase_C39 PF03412.15 CDJ51072.1 - 0.13 12.1 2.4 0.42 10.4 2.4 1.9 1 0 0 1 1 1 0 Peptidase C39 family LRRC37AB_C PF14914.6 CDJ51072.1 - 0.49 10.3 0.0 0.49 10.3 0.0 4.1 4 1 1 5 5 5 0 LRRC37A/B like protein 1 C-terminal domain SF1-HH PF16275.5 CDJ51075.1 - 0.064 13.6 1.1 0.18 12.2 1.1 1.7 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain DUF4834 PF16118.5 CDJ51075.1 - 0.092 13.7 0.3 0.092 13.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4778 PF16008.5 CDJ51075.1 - 0.46 10.5 5.4 0.9 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) Spt20 PF12090.8 CDJ51075.1 - 0.47 10.0 19.4 0.097 12.3 8.2 2.3 2 0 0 2 2 2 0 Spt20 family DUF572 PF04502.13 CDJ51075.1 - 2 7.9 11.7 3 7.4 11.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3381 PF11861.8 CDJ51075.1 - 2.8 7.7 11.0 7.7 6.3 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Dfp1_Him1_M PF08630.10 CDJ51075.1 - 4.8 7.4 9.4 5.8 7.1 0.2 3.1 2 1 1 3 3 3 0 Dfp1/Him1, central region DUF4834 PF16118.5 CDJ51076.1 - 5.8e-06 27.2 11.3 5.8e-06 27.2 11.3 4.0 2 2 1 3 3 2 1 Domain of unknown function (DUF4834) SARAF PF06682.12 CDJ51076.1 - 1.5e-05 24.8 13.9 1.5e-05 24.8 13.9 2.1 1 1 1 2 2 1 1 SOCE-associated regulatory factor of calcium homoeostasis Neur_chan_memb PF02932.16 CDJ51076.1 - 0.00017 21.8 18.9 0.00017 21.8 18.9 2.0 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region O-antigen_lig PF13425.6 CDJ51076.1 - 0.0026 16.6 4.7 0.0026 16.6 4.7 2.1 2 0 0 2 2 2 1 O-antigen ligase like membrane protein Peptidase_S49_N PF08496.10 CDJ51076.1 - 0.0052 16.9 23.0 0.0052 16.9 23.0 3.0 1 1 1 2 2 1 1 Peptidase family S49 N-terminal Choline_transpo PF04515.12 CDJ51076.1 - 0.029 13.6 0.4 0.052 12.7 0.2 1.4 1 1 0 1 1 1 0 Plasma-membrane choline transporter CD20 PF04103.15 CDJ51076.1 - 0.036 14.2 0.4 0.036 14.2 0.4 3.5 2 2 1 3 3 2 0 CD20-like family Wzy_C PF04932.15 CDJ51076.1 - 0.036 13.7 0.1 0.12 12.0 0.1 2.2 1 1 0 1 1 1 0 O-Antigen ligase MFS_1_like PF12832.7 CDJ51076.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.6 1 1 0 1 1 1 0 MFS_1 like family DUF4395 PF14340.6 CDJ51076.1 - 0.72 10.2 11.7 3.3 8.0 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) Membralin PF09746.9 CDJ51076.1 - 3.3 6.7 35.1 0.13 11.3 10.9 2.2 2 0 0 2 2 2 0 Tumour-associated protein CSG2 PF16965.5 CDJ51076.1 - 3.6 6.4 28.6 0.039 12.9 7.6 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator Shadoo PF14999.6 CDJ51077.1 - 0.029 14.5 5.4 0.035 14.2 5.4 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective BAF1_ABF1 PF04684.13 CDJ51077.1 - 0.071 12.2 16.8 0.082 11.9 16.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor BSP_II PF05432.11 CDJ51077.1 - 0.11 12.2 13.0 0.12 12.1 13.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PGA2 PF07543.12 CDJ51077.1 - 0.12 12.4 14.7 0.14 12.1 14.7 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 CobT PF06213.12 CDJ51077.1 - 0.15 11.4 19.8 0.19 11.1 19.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2052 PF09747.9 CDJ51077.1 - 0.23 11.6 15.4 0.27 11.3 15.4 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4175 PF13779.6 CDJ51077.1 - 0.25 9.2 24.3 0.27 9.1 24.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.10 CDJ51077.1 - 0.28 9.8 21.8 0.32 9.6 21.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Paf1 PF03985.13 CDJ51077.1 - 0.72 8.8 17.3 0.82 8.6 17.3 1.1 1 0 0 1 1 1 0 Paf1 Nop53 PF07767.11 CDJ51077.1 - 0.75 9.1 19.4 0.86 8.9 19.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 CDJ51077.1 - 0.76 8.0 13.1 0.85 7.8 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PMSI1 PF15322.6 CDJ51077.1 - 0.78 9.1 12.1 0.9 8.9 12.1 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative SprA-related PF12118.8 CDJ51077.1 - 0.9 8.6 28.4 1.1 8.3 28.4 1.1 1 0 0 1 1 1 0 SprA-related family GET2 PF08690.10 CDJ51077.1 - 1.1 8.8 13.7 1.4 8.6 13.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Pex14_N PF04695.13 CDJ51077.1 - 1.4 9.6 18.5 1.8 9.2 18.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ51077.1 - 1.5 8.5 6.2 1.6 8.4 6.2 1.2 1 0 0 1 1 1 0 Connexin DUF2868 PF11067.8 CDJ51077.1 - 1.8 8.0 14.0 2.2 7.7 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF4228 PF14009.6 CDJ51077.1 - 2.1 8.7 9.8 2.6 8.4 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) eIF-3_zeta PF05091.12 CDJ51077.1 - 3 6.7 15.2 3.3 6.6 15.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.13 CDJ51077.1 - 3.5 7.4 8.9 3.9 7.2 8.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 CDJ51077.1 - 3.6 7.6 8.7 3.7 7.5 8.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.12 CDJ51077.1 - 4.5 6.6 12.6 5.4 6.3 12.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger TFIIA PF03153.13 CDJ51077.1 - 5.8 6.8 28.5 7.5 6.4 28.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 CDJ51077.1 - 6 6.4 9.8 7.2 6.1 9.8 1.1 1 0 0 1 1 1 0 PPP4R2 K_channel_TID PF07941.11 CDJ51077.1 - 6.2 7.3 36.5 0.28 11.7 21.0 2.6 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF913 PF06025.12 CDJ51077.1 - 6.2 5.7 8.9 7.7 5.4 8.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CDJ51077.1 - 6.6 6.5 14.1 7.8 6.2 14.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 CDJ51077.1 - 7.4 6.7 17.5 8.8 6.4 17.5 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 CDJ51077.1 - 7.4 5.2 18.9 8.4 5.0 18.9 1.0 1 0 0 1 1 1 0 Presenilin MAJIN PF15077.6 CDJ51077.1 - 8.6 6.1 9.1 8.9 6.0 9.1 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Serinc PF03348.15 CDJ51077.1 - 8.8 5.1 6.8 11 4.8 6.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) RskA PF10099.9 CDJ51078.1 - 0.01 16.1 0.0 0.01 16.1 0.0 10.1 3 2 3 7 7 7 0 Anti-sigma-K factor rskA IMP2_N PF18590.1 CDJ51079.1 - 1.2e-28 99.5 0.0 1.7e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 CDJ51079.1 - 3.3e-24 84.5 0.0 5e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain Bromodomain PF00439.25 CDJ51080.1 - 2.1e-18 66.2 0.1 6.2e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 CDJ51080.1 - 4.1e-11 43.1 0.0 8.3e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ51080.1 - 5.5e-08 32.8 0.0 1.2e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ51080.1 - 3.2e-06 27.5 0.3 9.8e-06 25.9 0.3 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ51080.1 - 0.034 14.1 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 CDJ51080.1 - 0.16 12.0 0.1 0.43 10.7 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SfLAP PF11139.8 CDJ51080.1 - 4.8 6.6 6.5 9.4 5.6 6.5 1.4 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein Spt20 PF12090.8 CDJ51080.1 - 8.3 5.9 28.6 3.7 7.1 19.2 2.5 2 0 0 2 2 2 0 Spt20 family Macoilin PF09726.9 CDJ51081.1 - 0.026 13.1 5.3 0.037 12.6 5.3 1.2 1 0 0 1 1 1 0 Macoilin family Exonuc_VII_L PF02601.15 CDJ51081.1 - 0.057 13.0 10.0 0.15 11.6 9.7 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Ead_Ea22 PF13935.6 CDJ51081.1 - 0.065 13.9 7.9 0.16 12.6 7.9 1.8 1 1 0 1 1 1 0 Ead/Ea22-like protein Atg14 PF10186.9 CDJ51081.1 - 0.17 11.0 6.8 0.31 10.1 6.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 CDJ51081.1 - 0.31 11.2 4.3 0.39 10.9 2.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Plasmid_parti PF01672.16 CDJ51081.1 - 0.45 11.2 3.7 2.3 8.9 2.4 2.3 2 0 0 2 2 2 0 Putative plasmid partition protein FapA PF03961.13 CDJ51081.1 - 0.5 8.9 4.6 2.7 6.5 5.2 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A CREPT PF16566.5 CDJ51081.1 - 0.8 9.9 10.6 0.36 11.0 7.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Flg_hook PF02120.16 CDJ51081.1 - 3.6 7.5 9.3 0.45 10.4 0.1 3.7 3 1 0 3 3 3 0 Flagellar hook-length control protein FliK APG6_N PF17675.1 CDJ51082.1 - 0.004 17.7 10.5 0.004 17.7 10.5 2.1 2 0 0 2 2 2 1 Apg6 coiled-coil region HAP1_N PF04849.13 CDJ51082.1 - 0.0096 15.2 8.5 0.017 14.3 8.5 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ATG16 PF08614.11 CDJ51082.1 - 0.01 16.1 7.4 0.01 16.1 7.4 2.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 CDJ51082.1 - 0.02 15.0 8.1 0.02 15.0 8.1 2.0 2 0 0 2 2 2 0 Tropomyosin like Phlebovirus_NSM PF07246.11 CDJ51082.1 - 0.023 14.1 1.9 0.035 13.5 1.9 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M HMMR_N PF15905.5 CDJ51082.1 - 0.039 13.4 9.2 0.019 14.4 6.5 1.7 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Mod_r PF07200.13 CDJ51082.1 - 0.046 13.8 13.5 0.11 12.6 8.7 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Csm1_N PF18504.1 CDJ51082.1 - 0.054 13.8 10.1 0.39 11.1 1.1 2.9 3 0 0 3 3 3 0 Csm1 N-terminal domain PAH PF02671.21 CDJ51082.1 - 0.07 13.3 0.2 0.15 12.2 0.2 1.6 1 0 0 1 1 1 0 Paired amphipathic helix repeat HAUS-augmin3 PF14932.6 CDJ51082.1 - 0.077 12.6 11.8 0.033 13.8 7.1 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 CDJ51082.1 - 0.11 11.4 9.8 0.035 13.0 6.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 CDJ51082.1 - 0.15 12.3 13.8 0.13 12.5 8.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Prefoldin PF02996.17 CDJ51082.1 - 0.18 11.7 11.6 6.6 6.7 1.1 3.1 3 0 0 3 3 3 0 Prefoldin subunit GIT_CC PF16559.5 CDJ51082.1 - 0.34 10.8 10.9 1.7 8.6 3.1 2.6 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_DNA_bd PF12329.8 CDJ51082.1 - 0.39 10.8 15.7 0.43 10.6 2.3 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Uso1_p115_C PF04871.13 CDJ51082.1 - 0.88 9.9 13.2 0.25 11.7 9.0 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF948 PF06103.11 CDJ51082.1 - 1.4 9.3 6.0 19 5.6 4.5 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.8 CDJ51082.1 - 2 8.5 17.1 0.91 9.6 12.5 2.3 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding FUSC PF04632.12 CDJ51082.1 - 2 6.8 6.7 1.1 7.7 5.1 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF16 PF01519.16 CDJ51082.1 - 2.5 8.6 10.8 2.1 8.9 8.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 PRKG1_interact PF15898.5 CDJ51082.1 - 2.6 9.0 13.8 1.5 9.7 8.9 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FAM76 PF16046.5 CDJ51082.1 - 3.1 7.0 9.2 1.6 8.0 6.2 1.7 2 0 0 2 2 2 0 FAM76 protein Pedibin PF08182.11 CDJ51082.1 - 3.3 7.6 8.2 0.25 11.2 2.1 2.2 2 0 0 2 2 2 0 Pedibin/Hym-346 family Phage_GP20 PF06810.11 CDJ51082.1 - 5.4 6.8 12.3 2.1 8.2 7.1 2.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 BRE1 PF08647.11 CDJ51082.1 - 5.8 7.0 13.9 72 3.5 10.8 2.7 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4094 PF13334.6 CDJ51082.1 - 6 7.4 7.2 1.8 9.0 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) MMR_HSR1 PF01926.23 CDJ51083.1 - 1.8e-16 60.2 0.1 3.5e-15 56.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ51083.1 - 4.8e-06 26.6 0.1 0.0023 17.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CDJ51083.1 - 1.1e-05 25.0 0.2 2.6e-05 23.8 0.1 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ51083.1 - 0.025 14.6 1.3 0.27 11.3 0.2 3.0 3 1 1 4 4 4 0 Dynamin family Roc PF08477.13 CDJ51083.1 - 0.13 12.5 0.1 10 6.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BT1 PF03092.16 CDJ51084.1 - 2.4e-12 45.9 14.0 0.00042 18.7 0.2 3.3 2 1 1 3 3 3 3 BT1 family MFS_1 PF07690.16 CDJ51084.1 - 0.0038 16.2 15.0 0.0038 16.2 15.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Mt_ATP-synt_B PF05405.14 CDJ51084.1 - 0.027 14.1 1.6 0.058 13.0 1.6 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3562 PF12085.8 CDJ51084.1 - 0.12 12.0 0.1 1.2 8.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3562) STT3 PF02516.14 CDJ51085.1 - 2.2e-79 267.7 32.7 3.2e-79 267.1 32.7 1.2 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit MAP17 PF15807.5 CDJ51085.1 - 0.72 10.1 1.7 1.7 8.9 1.7 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 WD40 PF00400.32 CDJ51087.1 - 0.071 14.0 6.4 0.56 11.2 0.2 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat F-box PF00646.33 CDJ51087.1 - 0.076 12.9 0.0 0.36 10.8 0.0 2.2 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 CDJ51087.1 - 0.085 12.8 0.1 0.36 10.8 0.1 2.2 1 0 0 1 1 1 0 F-box-like BDV_P10 PF06515.11 CDJ51087.1 - 0.37 10.9 2.7 1.7 8.7 2.7 2.2 1 0 0 1 1 1 0 Borna disease virus P10 protein FUSC_2 PF13515.6 CDJ51088.1 - 6.5e-13 48.9 6.3 6.5e-13 48.9 6.3 3.5 3 2 0 3 3 3 1 Fusaric acid resistance protein-like TetR_C_16 PF17920.1 CDJ51088.1 - 1.1 9.5 6.3 1.9 8.8 0.0 4.1 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain MMtag PF10159.9 CDJ51089.1 - 5.4e-18 65.0 2.1 5.4e-18 65.0 2.1 4.8 4 2 0 4 4 4 1 Multiple myeloma tumor-associated Kinase-like PF14531.6 CDJ51089.1 - 0.16 11.2 2.3 0.27 10.5 2.3 1.3 1 0 0 1 1 1 0 Kinase-like E1-E2_ATPase PF00122.20 CDJ51090.1 - 4.2e-35 120.9 2.9 1.6e-34 119.0 0.0 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDJ51090.1 - 2.9e-33 115.1 1.1 2.9e-33 115.1 1.1 3.7 5 0 0 5 5 5 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CDJ51090.1 - 1.7e-15 57.8 0.5 6.4e-09 36.4 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ51090.1 - 4.1e-14 52.4 0.1 8e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CDJ51090.1 - 3.4e-07 29.8 0.0 1.1e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDJ51090.1 - 0.00069 19.4 0.5 0.0019 18.0 0.5 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PAP_central PF04928.17 CDJ51090.1 - 0.17 10.8 0.5 0.41 9.6 0.2 1.7 2 0 0 2 2 2 0 Poly(A) polymerase central domain AMP-binding PF00501.28 CDJ51091.1 - 4.8e-19 68.3 0.1 7.4e-19 67.6 0.0 1.3 2 0 0 2 2 2 1 AMP-binding enzyme ACAS_N PF16177.5 CDJ51091.1 - 3.8e-17 62.0 1.9 6e-17 61.3 1.9 1.3 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus PPL5 PF18168.1 CDJ51092.1 - 2 7.6 23.5 2.2 7.5 23.5 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S49_N PF08496.10 CDJ51093.1 - 3 7.9 14.2 3.2 7.8 14.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 CDJ51093.1 - 9.1 4.9 15.4 9.7 4.8 15.4 1.0 1 0 0 1 1 1 0 Presenilin DUF1980 PF09323.10 CDJ51095.1 - 0.0038 17.2 2.9 0.0038 17.2 2.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1980) Pex16 PF08610.10 CDJ51095.1 - 0.11 11.7 5.3 0.2 10.8 5.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4820 PF16091.5 CDJ51095.1 - 0.15 11.4 13.5 0.047 13.0 7.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) CEL_III_C PF18054.1 CDJ51095.1 - 0.25 11.4 6.2 0.58 10.2 6.2 1.5 1 0 0 1 1 1 0 CEL-III C-terminal DUF3843 PF12954.7 CDJ51095.1 - 0.47 9.4 7.9 0.73 8.7 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) Smg8_Smg9 PF10220.9 CDJ51095.1 - 0.7 8.1 10.1 0.97 7.7 10.1 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Otopetrin PF03189.13 CDJ51095.1 - 0.96 8.2 5.6 1.5 7.6 5.6 1.2 1 0 0 1 1 1 0 Otopetrin FAM60A PF15396.6 CDJ51095.1 - 1.4 8.8 7.5 3.3 7.7 7.5 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Folliculin PF11704.8 CDJ51095.1 - 2.8 7.8 9.5 0.93 9.3 6.1 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport MBR1 PF17058.5 CDJ51095.1 - 4.7 7.5 11.8 3.4 7.9 8.9 1.9 2 0 0 2 2 2 0 Mitochondrial biogenesis regulation protein 1 Miga PF10265.9 CDJ51095.1 - 5.3 5.9 11.9 8.8 5.2 11.9 1.4 1 0 0 1 1 1 0 Mitoguardin Hid1 PF12722.7 CDJ51095.1 - 6.8 4.7 15.0 9.6 4.2 15.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2052 PF09747.9 CDJ51096.1 - 0.0021 18.2 6.9 0.0024 18.0 6.9 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) FAM60A PF15396.6 CDJ51096.1 - 0.011 15.7 2.1 0.013 15.5 2.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SprA-related PF12118.8 CDJ51096.1 - 0.026 13.7 26.9 0.038 13.1 26.9 1.2 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.13 CDJ51096.1 - 0.029 14.4 31.1 0.038 14.0 31.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SMYLE_N PF18615.1 CDJ51096.1 - 0.049 13.2 6.6 0.057 13.0 6.6 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SOBP PF15279.6 CDJ51096.1 - 0.27 11.8 8.9 0.3 11.7 8.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Tfb4 PF03850.14 CDJ51096.1 - 0.28 10.7 4.8 0.33 10.4 4.8 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 Presenilin PF01080.17 CDJ51096.1 - 0.34 9.6 12.7 0.39 9.4 12.7 1.1 1 0 0 1 1 1 0 Presenilin DUF4228 PF14009.6 CDJ51096.1 - 0.41 11.0 6.7 0.58 10.5 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF572 PF04502.13 CDJ51096.1 - 0.48 10.0 11.0 0.58 9.7 11.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Bud13 PF09736.9 CDJ51096.1 - 0.52 10.7 15.2 0.76 10.2 15.2 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex RR_TM4-6 PF06459.12 CDJ51096.1 - 0.58 9.9 11.7 0.75 9.6 11.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S46 PF10459.9 CDJ51096.1 - 0.68 8.5 14.2 0.79 8.3 14.2 1.0 1 0 0 1 1 1 0 Peptidase S46 Connexin PF00029.19 CDJ51096.1 - 0.7 9.6 3.2 0.86 9.3 3.2 1.2 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 CDJ51096.1 - 0.88 9.6 8.1 1.3 9.0 8.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OATP PF03137.20 CDJ51096.1 - 0.95 7.7 3.2 1.2 7.4 3.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family V_ATPase_I PF01496.19 CDJ51096.1 - 1.8 6.4 8.6 1.9 6.3 8.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAT1 PF09770.9 CDJ51096.1 - 1.8 6.7 21.5 2 6.6 21.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3450 PF11932.8 CDJ51096.1 - 2 7.6 29.1 2.8 7.2 29.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) KdgT PF03812.13 CDJ51096.1 - 2.1 7.6 7.3 3 7.1 6.6 1.5 2 0 0 2 2 2 0 2-keto-3-deoxygluconate permease TFB6 PF17110.5 CDJ51096.1 - 2.5 7.8 5.2 3.7 7.3 5.2 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Suf PF05843.14 CDJ51096.1 - 2.7 7.9 15.1 3.4 7.6 15.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SLC12 PF03522.15 CDJ51096.1 - 4.9 6.1 11.0 6.1 5.8 11.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MAJIN PF15077.6 CDJ51096.1 - 7.3 6.3 8.5 8.8 6.0 8.5 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein ALMT PF11744.8 CDJ51096.1 - 8.4 5.1 8.3 10 4.9 8.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MID_MedPIWI PF18296.1 CDJ51097.1 - 3.4 7.4 13.4 6.1 6.5 7.8 2.6 2 1 0 2 2 2 0 MID domain of medPIWI Apt1 PF10351.9 CDJ51097.1 - 6.6 5.5 13.2 17 4.1 13.2 1.9 1 1 0 1 1 1 0 Golgi-body localisation protein domain GRASP55_65 PF04495.14 CDJ51099.1 - 3.6e-05 24.1 0.0 5.5e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain DUF2992 PF11208.8 CDJ51099.1 - 0.025 14.8 17.1 0.031 14.5 17.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) eIF-3_zeta PF05091.12 CDJ51099.1 - 0.038 13.0 14.3 0.039 12.9 14.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Serinc PF03348.15 CDJ51099.1 - 0.23 10.3 5.8 0.26 10.2 5.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) EOS1 PF12326.8 CDJ51099.1 - 0.35 10.8 3.0 0.36 10.7 3.0 1.2 1 0 0 1 1 1 0 N-glycosylation protein Neur_chan_memb PF02932.16 CDJ51099.1 - 1.2 9.1 10.2 1.4 9.0 10.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hydin_ADK PF17213.3 CDJ51099.1 - 1.4 9.2 10.2 1.7 8.9 10.2 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF4471 PF14740.6 CDJ51099.1 - 1.5 8.0 11.5 1.9 7.7 11.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) AAA_23 PF13476.6 CDJ51099.1 - 2.7 8.4 17.0 2.9 8.3 17.0 1.1 1 0 0 1 1 1 0 AAA domain Suf PF05843.14 CDJ51099.1 - 2.8 7.8 19.4 3.9 7.4 19.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Kei1 PF08552.11 CDJ51099.1 - 3.5 7.5 5.3 4 7.3 5.3 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FAM176 PF14851.6 CDJ51099.1 - 4.5 6.9 8.4 2.4 7.8 5.9 1.7 2 0 0 2 2 2 0 FAM176 family Connexin PF00029.19 CDJ51099.1 - 4.8 6.9 10.5 6 6.5 10.5 1.2 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.19 CDJ51099.1 - 5 4.9 15.2 5.5 4.8 15.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 CDJ51099.1 - 5.2 6.0 8.6 5.8 5.8 8.6 1.2 1 0 0 1 1 1 0 CLN3 protein Pet20 PF08692.10 CDJ51099.1 - 6.1 7.6 9.8 11 6.8 9.8 1.6 1 1 0 1 1 1 0 Mitochondrial protein Pet20 OATP PF03137.20 CDJ51099.1 - 8.3 4.6 10.6 11 4.1 10.6 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SDA1 PF05285.12 CDJ51100.1 - 1.2e-07 31.5 32.8 2.6e-07 30.4 14.5 2.4 2 0 0 2 2 2 2 SDA1 Lin-8 PF03353.15 CDJ51100.1 - 0.00014 21.6 25.5 0.00014 21.6 25.5 3.1 2 1 1 3 3 3 1 Ras-mediated vulval-induction antagonist DUF572 PF04502.13 CDJ51100.1 - 0.095 12.3 48.0 0.28 10.8 13.7 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF572) SPX PF03105.19 CDJ51100.1 - 0.22 11.4 51.0 0.26 11.2 18.2 2.5 2 1 0 2 2 2 0 SPX domain MRP-S31 PF15433.6 CDJ51100.1 - 0.62 9.7 50.0 0.49 10.0 16.0 3.1 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S31 NAD_binding_1 PF00175.21 CDJ51101.1 - 1.1e-14 55.0 6.5 1.6e-09 38.4 0.3 3.6 3 1 1 4 4 4 2 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.25 CDJ51101.1 - 0.00016 21.9 0.2 0.0072 16.5 0.2 3.2 1 1 0 1 1 1 1 Flavodoxin NAD_binding_6 PF08030.12 CDJ51101.1 - 0.075 13.1 0.2 0.075 13.1 0.2 4.6 4 3 0 4 4 4 0 Ferric reductase NAD binding domain Spt20 PF12090.8 CDJ51101.1 - 2.5 7.7 83.9 0.03 13.9 2.0 6.0 6 0 0 6 6 6 0 Spt20 family Trehalose_PPase PF02358.16 CDJ51102.1 - 4e-10 39.2 0.0 1.5e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Trehalose-phosphatase AF-4 PF05110.13 CDJ51103.1 - 0.072 11.2 43.1 0.1 10.7 43.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2681 PF10883.8 CDJ51106.1 - 0.0016 18.8 9.0 0.0016 18.8 9.0 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2681) Mannosyl_trans2 PF04188.13 CDJ51106.1 - 0.29 10.4 2.7 0.42 9.9 2.7 1.1 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) SMYLE_N PF18615.1 CDJ51106.1 - 8.6 5.8 24.3 13 5.2 24.3 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Flavokinase PF01687.17 CDJ51107.1 - 3.9e-09 36.8 0.0 7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase MAM33 PF02330.16 CDJ51107.1 - 2 8.3 22.9 0.94 9.4 12.2 3.0 3 0 0 3 3 3 0 Mitochondrial glycoprotein V_ATPase_I PF01496.19 CDJ51107.1 - 3.9 5.3 22.3 0.94 7.3 12.9 2.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GAGA_bind PF06217.12 CDJ51107.1 - 6.8 6.9 25.2 0.21 11.9 8.8 2.6 3 0 0 3 3 3 0 GAGA binding protein-like family Pkinase PF00069.25 CDJ51108.1 - 8e-14 51.6 0.0 1.2e-11 44.6 0.0 4.6 4 1 0 5 5 5 2 Protein kinase domain DUF2722 PF10846.8 CDJ51108.1 - 3.4e-05 23.0 7.1 3.4e-05 23.0 7.1 8.1 2 1 5 8 8 8 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ51108.1 - 0.0071 16.4 14.3 0.0071 16.4 14.3 4.6 2 1 3 5 5 5 1 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 CDJ51108.1 - 0.079 13.3 0.3 0.079 13.3 0.3 6.2 3 1 0 3 3 3 0 Enhancer of polycomb-like SR-25 PF10500.9 CDJ51109.1 - 0.0074 15.9 21.2 0.0074 15.9 21.2 4.2 3 1 1 4 4 4 4 Nuclear RNA-splicing-associated protein SARAF PF06682.12 CDJ51110.1 - 0.0029 17.3 2.5 0.004 16.9 2.5 1.3 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Trp_oprn_chp PF09534.10 CDJ51110.1 - 0.0083 15.9 0.3 0.01 15.7 0.3 1.0 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CSG2 PF16965.5 CDJ51110.1 - 0.015 14.3 7.1 0.018 14.0 7.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Frizzled PF01534.17 CDJ51110.1 - 0.017 14.2 0.5 0.02 14.0 0.5 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Peptidase_M56 PF05569.11 CDJ51110.1 - 0.025 13.8 2.0 0.027 13.6 2.0 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 Renin_r PF07850.14 CDJ51110.1 - 0.041 14.5 0.9 0.041 14.5 0.9 2.1 1 1 1 2 2 2 0 Renin receptor-like protein DUF4834 PF16118.5 CDJ51110.1 - 0.063 14.2 2.2 0.063 14.2 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) AIF_C PF14721.6 CDJ51110.1 - 0.073 13.4 5.5 2.7 8.3 1.6 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Erv26 PF04148.13 CDJ51110.1 - 0.092 12.6 3.0 0.11 12.4 3.0 1.1 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 Presenilin PF01080.17 CDJ51110.1 - 0.17 10.6 10.0 0.24 10.1 10.0 1.2 1 0 0 1 1 1 0 Presenilin PIP5K PF01504.18 CDJ51110.1 - 0.18 11.0 6.4 0.21 10.8 6.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase VanZ PF04892.12 CDJ51110.1 - 0.23 12.1 0.1 0.23 12.1 0.1 1.7 2 0 0 2 2 1 0 VanZ like family SID-1_RNA_chan PF13965.6 CDJ51110.1 - 0.38 9.1 4.3 0.48 8.8 4.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FHIPEP PF00771.20 CDJ51110.1 - 0.45 8.9 11.3 7.5 4.9 11.8 1.9 1 1 1 2 2 2 0 FHIPEP family EphA2_TM PF14575.6 CDJ51110.1 - 0.61 11.0 8.6 7.8 7.5 0.2 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Spt20 PF12090.8 CDJ51110.1 - 0.74 9.4 42.4 1.6 8.3 18.2 2.1 2 0 0 2 2 2 0 Spt20 family EPL1 PF10513.9 CDJ51110.1 - 0.86 10.0 10.3 3.7 7.9 1.2 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like SKIP_SNW PF02731.15 CDJ51110.1 - 1.1 8.9 16.2 0.53 10.0 3.1 2.1 2 0 0 2 2 2 0 SKIP/SNW domain WRNPLPNID PF15017.6 CDJ51110.1 - 2.5 9.1 8.0 8.3 7.4 2.0 2.2 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box RRP14 PF15459.6 CDJ51110.1 - 2.7 8.7 16.0 6.8 7.4 3.2 2.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 ALMT PF11744.8 CDJ51110.1 - 2.7 6.7 7.9 3.7 6.3 7.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter EOS1 PF12326.8 CDJ51110.1 - 2.8 7.9 12.4 0.23 11.4 0.3 2.0 1 1 1 2 2 2 0 N-glycosylation protein DUF5362 PF17319.2 CDJ51110.1 - 3.3 7.6 5.1 0.73 9.7 1.2 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5362) MTABC_N PF16185.5 CDJ51110.1 - 3.7 7.0 9.3 1.2 8.6 5.6 1.7 1 1 1 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region eIF_4EBP PF05456.11 CDJ51110.1 - 4.2 7.4 12.4 3.7 7.5 2.7 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF979 PF06166.12 CDJ51110.1 - 6.2 5.9 5.6 1.3 8.1 2.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF979) DUF5327 PF17261.2 CDJ51110.1 - 6.3 7.6 21.4 3.8 8.3 5.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Orf78 PF06024.12 CDJ51110.1 - 6.3 7.2 13.5 0.43 10.9 0.9 2.1 1 1 1 2 2 2 0 Orf78 (ac78) FAM70 PF14967.6 CDJ51110.1 - 7.8 5.9 11.3 9.8 5.5 5.2 2.0 1 1 1 2 2 2 0 FAM70 protein Med15 PF09606.10 CDJ51110.1 - 7.9 5.0 32.6 0.97 8.0 13.2 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal CbiM PF01891.16 CDJ51111.1 - 0.026 14.4 8.8 0.074 12.9 6.2 2.1 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region Caldesmon PF02029.15 CDJ51112.1 - 7.4 5.2 38.0 5.2 5.7 27.0 3.2 3 0 0 3 3 3 0 Caldesmon PHD_2 PF13831.6 CDJ51113.1 - 7.6e-07 28.6 1.3 7.6e-07 28.6 1.3 2.3 2 0 0 2 2 2 1 PHD-finger RskA PF10099.9 CDJ51113.1 - 2e-05 24.9 3.9 2e-05 24.9 3.9 3.0 2 1 1 3 3 2 1 Anti-sigma-K factor rskA DUF4647 PF15504.6 CDJ51113.1 - 0.0033 16.6 14.1 0.0049 16.0 14.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4647) PHD PF00628.29 CDJ51113.1 - 0.0096 15.8 3.7 0.0096 15.8 3.7 2.5 2 0 0 2 2 2 1 PHD-finger SpoIIP PF07454.11 CDJ51113.1 - 0.03 13.8 7.7 0.04 13.4 7.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) C1_1 PF00130.22 CDJ51113.1 - 0.039 13.8 3.6 0.11 12.4 3.6 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TMEM208_SND2 PF05620.11 CDJ51113.1 - 0.055 13.2 0.8 0.095 12.5 0.8 1.5 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 NARP1 PF12569.8 CDJ51113.1 - 0.058 12.3 4.6 0.079 11.9 4.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Spt20 PF12090.8 CDJ51113.1 - 0.086 12.4 40.7 0.15 11.7 40.7 1.3 1 0 0 1 1 1 0 Spt20 family Prok-RING_1 PF14446.6 CDJ51113.1 - 0.1 12.6 3.6 0.24 11.3 3.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Cwf_Cwc_15 PF04889.12 CDJ51113.1 - 0.18 11.5 15.4 0.3 10.8 15.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4746 PF15928.5 CDJ51113.1 - 0.18 11.2 2.8 0.23 10.8 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PNISR PF15996.5 CDJ51113.1 - 0.3 11.4 20.9 0.56 10.5 20.9 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Folate_carrier PF01770.18 CDJ51113.1 - 0.38 9.4 2.0 0.5 9.1 2.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier SLC12 PF03522.15 CDJ51113.1 - 0.45 9.5 14.4 0.57 9.1 14.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CDJ51113.1 - 0.52 7.4 23.3 0.81 6.7 23.3 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ51113.1 - 0.8 7.9 21.7 1.1 7.5 21.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 G0-G1_switch_2 PF15103.6 CDJ51113.1 - 0.88 10.0 9.3 1.8 9.0 9.3 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 Roughex PF06020.11 CDJ51113.1 - 0.93 8.5 13.2 1.7 7.7 13.2 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Tim54 PF11711.8 CDJ51113.1 - 1.1 7.9 9.4 1.5 7.5 9.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EIIBC-GUT_N PF03612.14 CDJ51113.1 - 1.3 8.8 8.2 2.2 8.0 8.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3807 PF12720.7 CDJ51113.1 - 2.1 8.6 22.4 4.4 7.5 22.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) eIF-3_zeta PF05091.12 CDJ51113.1 - 2.5 7.0 18.6 3.4 6.5 18.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4770 PF15994.5 CDJ51113.1 - 4.3 7.5 13.5 7.1 6.8 13.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) V_ATPase_I PF01496.19 CDJ51113.1 - 4.7 5.0 12.8 6.3 4.6 12.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LCD1 PF09798.9 CDJ51113.1 - 4.7 5.6 10.9 6 5.3 10.9 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Connexin PF00029.19 CDJ51113.1 - 5 6.8 8.2 7.4 6.3 8.2 1.3 1 0 0 1 1 1 0 Connexin Sec62 PF03839.16 CDJ51113.1 - 7.7 6.0 8.1 11 5.5 8.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Membralin PF09746.9 CDJ51113.1 - 9.5 5.1 6.5 12 4.8 6.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein CytochromB561_N PF09786.9 CDJ51113.1 - 9.7 5.0 31.9 16 4.3 31.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal SelP_N PF04592.14 CDJ51114.1 - 0.26 10.7 34.1 0.019 14.3 27.3 1.9 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF719 PF05334.13 CDJ51114.1 - 0.96 9.6 18.9 0.082 13.1 10.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF4820 PF16091.5 CDJ51114.1 - 2.7 7.3 13.5 1.6 8.1 5.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) TCP PF03634.13 CDJ51114.1 - 3.2 8.3 21.8 0.91 10.1 12.3 2.2 2 0 0 2 2 2 0 TCP family transcription factor Connexin PF00029.19 CDJ51114.1 - 3.6 7.3 9.0 0.22 11.3 0.9 2.1 2 0 0 2 2 2 0 Connexin FAM176 PF14851.6 CDJ51114.1 - 4.9 6.8 8.1 0.64 9.7 2.4 2.1 2 0 0 2 2 2 0 FAM176 family IMUP PF15761.5 CDJ51115.1 - 0.025 15.3 9.4 0.025 15.3 9.4 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein Pro_racemase PF05544.11 CDJ51116.1 - 7.1 5.6 11.6 7.7 5.5 11.6 1.0 1 0 0 1 1 1 0 Proline racemase TFIIA PF03153.13 CDJ51117.1 - 1.3e-07 32.0 38.7 2.3e-07 31.2 5.6 7.4 3 1 3 7 7 7 2 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ51117.1 - 0.0002 19.7 61.4 0.0002 19.7 61.4 9.9 9 2 1 10 10 10 1 AF-4 proto-oncoprotein SPX PF03105.19 CDJ51117.1 - 4.4 7.1 0.0 0.13 12.1 19.1 7.7 5 3 0 6 6 6 0 SPX domain SPX PF03105.19 CDJ51118.1 - 0.0048 16.9 17.1 0.005 16.8 17.1 1.1 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 CDJ51118.1 - 0.07 12.0 17.5 0.078 11.8 17.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SLD3 PF08639.10 CDJ51118.1 - 0.21 10.3 20.8 0.23 10.2 20.8 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 NST1 PF13945.6 CDJ51118.1 - 0.35 11.0 28.4 0.51 10.4 28.4 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator PNISR PF15996.5 CDJ51118.1 - 0.44 10.8 25.0 0.59 10.4 25.0 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Presenilin PF01080.17 CDJ51118.1 - 0.58 8.9 24.7 0.71 8.6 24.7 1.2 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 CDJ51118.1 - 0.6 9.5 13.8 0.86 9.0 13.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein V_ATPase_I PF01496.19 CDJ51118.1 - 0.98 7.2 15.0 1.4 6.7 15.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 CDJ51118.1 - 1.1 7.9 22.4 1.3 7.6 22.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.15 CDJ51118.1 - 1.4 8.5 26.8 1.8 8.1 26.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SRP-alpha_N PF04086.13 CDJ51118.1 - 1.4 8.8 26.1 1.7 8.5 26.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CCSAP PF15748.5 CDJ51118.1 - 1.5 9.0 28.8 2.1 8.5 28.8 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PAT1 PF09770.9 CDJ51118.1 - 1.8 6.7 32.8 2.1 6.5 32.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Draxin PF15550.6 CDJ51118.1 - 1.8 8.3 20.1 2.3 8.0 20.1 1.1 1 0 0 1 1 1 0 Draxin SYF2 PF08231.12 CDJ51118.1 - 2.1 8.7 17.8 3.2 8.2 17.8 1.2 1 0 0 1 1 1 0 SYF2 splicing factor Sporozoite_P67 PF05642.11 CDJ51118.1 - 2.8 5.9 14.2 3.3 5.7 14.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM220 PF15487.6 CDJ51118.1 - 3.3 7.3 20.6 4.6 6.8 20.6 1.2 1 0 0 1 1 1 0 FAM220 family SLC12 PF03522.15 CDJ51118.1 - 3.5 6.5 21.2 4.3 6.2 21.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 CDJ51118.1 - 3.6 5.7 19.3 4.4 5.5 19.3 1.1 1 0 0 1 1 1 0 CDC45-like protein XRN_M PF17846.1 CDJ51118.1 - 3.7 6.4 12.6 4.6 6.1 12.6 1.3 1 0 0 1 1 1 0 Xrn1 helical domain ALMT PF11744.8 CDJ51118.1 - 4.4 6.0 16.9 5.7 5.6 16.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_S64 PF08192.11 CDJ51118.1 - 4.7 5.6 25.0 5.3 5.4 25.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Cellulose_synt PF03552.14 CDJ51118.1 - 5.3 5.4 8.4 6 5.2 8.4 1.1 1 0 0 1 1 1 0 Cellulose synthase SOG2 PF10428.9 CDJ51118.1 - 5.9 6.0 28.0 7.4 5.7 28.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 CDJ51118.1 - 6.1 3.8 27.1 6.5 3.7 27.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Membralin PF09746.9 CDJ51118.1 - 9.3 5.2 12.0 11 4.9 12.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein FF PF01846.19 CDJ51121.1 - 0.33 11.2 2.5 0.23 11.7 0.8 1.7 2 0 0 2 2 2 0 FF domain RAP PF08373.10 CDJ51122.1 - 3.5e-11 43.0 0.0 1.1e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 RAP domain Spt20 PF12090.8 CDJ51122.1 - 0.00019 21.1 9.8 0.00019 21.1 9.8 24.1 16 7 2 18 18 18 5 Spt20 family Activator_LAG-3 PF11498.8 CDJ51122.1 - 0.00035 19.7 17.9 0.00035 19.7 17.9 19.1 16 4 3 19 19 19 2 Transcriptional activator LAG-3 RskA PF10099.9 CDJ51122.1 - 0.00041 20.7 9.2 0.00041 20.7 9.2 29.3 10 10 15 25 25 25 5 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ51122.1 - 0.00054 19.0 6.0 0.00054 19.0 6.0 23.4 17 4 3 21 21 21 6 Protein of unknown function (DUF2722) Oscp1 PF10188.9 CDJ51124.1 - 0.16 12.0 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 Organic solute transport protein 1 Aminotran_5 PF00266.19 CDJ51125.1 - 0.1 11.5 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Aminotransferase class-V FA_desaturase PF00487.24 CDJ51126.1 - 0.035 13.9 1.7 0.035 13.9 1.7 1.0 1 0 0 1 1 1 0 Fatty acid desaturase Trp_oprn_chp PF09534.10 CDJ51126.1 - 0.082 12.7 29.1 0.097 12.5 29.1 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3742 PF12553.8 CDJ51126.1 - 0.31 11.2 9.7 0.38 10.9 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) R_equi_Vir PF05526.11 CDJ51126.1 - 4.8 7.0 11.5 6.3 6.6 11.5 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RskA PF10099.9 CDJ51127.1 - 1.7e-06 28.4 10.9 1.7e-06 28.4 10.9 7.2 1 1 6 7 7 7 2 Anti-sigma-K factor rskA GHMP_kinases_N PF00288.26 CDJ51127.1 - 0.0002 21.5 0.0 0.0002 21.5 0.0 8.6 6 2 0 6 6 6 1 GHMP kinases N terminal domain Activator_LAG-3 PF11498.8 CDJ51127.1 - 0.0038 16.3 22.2 0.0038 16.3 22.2 4.3 4 0 0 4 4 4 3 Transcriptional activator LAG-3 Lin-8 PF03353.15 CDJ51127.1 - 0.12 12.0 30.1 1.6 8.3 1.1 4.3 4 0 0 4 4 4 0 Ras-mediated vulval-induction antagonist DUF4667 PF15700.5 CDJ51127.1 - 0.63 10.1 32.8 0.2 11.8 2.3 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ51128.1 - 0.00017 21.7 19.7 0.00017 21.7 19.7 2.7 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.11 CDJ51128.1 - 0.0022 16.6 12.1 0.0022 16.6 12.1 2.5 3 0 0 3 3 3 1 Peptidase family S64 CWC25 PF12542.8 CDJ51128.1 - 0.0059 17.5 7.0 0.0059 17.5 7.0 4.2 4 1 0 4 4 4 1 Pre-mRNA splicing factor RskA PF10099.9 CDJ51128.1 - 0.015 15.6 4.0 0.015 15.6 4.0 6.5 2 2 4 6 6 6 0 Anti-sigma-K factor rskA TctB PF07331.11 CDJ51128.1 - 1 9.6 4.9 5.9 7.2 5.6 2.0 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Rhodanese PF00581.20 CDJ51129.1 - 1.3e-05 25.6 2.5 3.5e-05 24.3 0.5 2.9 2 0 0 2 2 2 1 Rhodanese-like domain SR-25 PF10500.9 CDJ51129.1 - 0.00012 21.8 29.2 0.00012 21.8 29.2 10.0 6 2 2 10 10 10 4 Nuclear RNA-splicing-associated protein PAP1 PF08601.10 CDJ51129.1 - 0.00034 20.4 0.0 0.00034 20.4 0.0 7.2 4 1 0 5 5 5 2 Transcription factor PAP1 SUIM_assoc PF16619.5 CDJ51130.1 - 0.0083 16.2 3.3 0.0083 16.2 3.3 6.4 4 2 1 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 GNT-I PF03071.15 CDJ51130.1 - 0.028 13.2 7.9 0.062 12.1 7.9 1.5 1 0 0 1 1 1 0 GNT-I family PepSY_TM_like_2 PF16357.5 CDJ51130.1 - 0.11 12.4 0.0 0.11 12.4 0.0 3.2 2 1 1 4 4 4 0 Putative PepSY_TM-like SID-1_RNA_chan PF13965.6 CDJ51130.1 - 3 6.2 9.4 0.5 8.7 5.5 1.7 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 CRR7 PF12095.8 CDJ51132.1 - 0.47 10.9 3.0 0.41 11.1 0.8 1.8 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 TFIIA PF03153.13 CDJ51133.1 - 0.11 12.5 33.7 0.15 12.1 33.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ51133.1 - 0.52 8.2 10.9 0.63 7.9 10.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF-3_zeta PF05091.12 CDJ51133.1 - 0.57 9.1 14.9 0.64 8.9 14.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HemX PF04375.14 CDJ51133.1 - 0.88 8.8 26.5 1.2 8.4 26.5 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Serinc PF03348.15 CDJ51133.1 - 0.99 8.3 6.6 1.3 7.9 6.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) MMR1 PF08505.10 CDJ51133.1 - 1 9.6 18.8 1.4 9.1 18.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PA26 PF04636.13 CDJ51133.1 - 1.1 8.1 8.6 1.2 7.9 8.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Neur_chan_memb PF02932.16 CDJ51133.1 - 1.2 9.1 10.6 1.5 8.8 10.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ51133.1 - 1.4 7.6 18.7 1.6 7.4 18.7 1.0 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 CDJ51133.1 - 1.6 8.3 15.0 1.9 8.0 15.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) SMYLE_N PF18615.1 CDJ51133.1 - 1.9 8.0 11.7 2.2 7.7 11.7 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SLC12 PF03522.15 CDJ51133.1 - 2.6 7.0 12.9 3.1 6.7 12.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Coilin_N PF15862.5 CDJ51133.1 - 3.1 7.6 14.8 2.8 7.7 10.5 2.1 2 0 0 2 2 2 0 Coilin N-terminus GTA_holin_3TM PF11351.8 CDJ51133.1 - 3.5 8.2 15.9 3 8.4 8.3 2.2 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release TERB2 PF15101.6 CDJ51133.1 - 3.7 7.5 19.0 1.7 8.7 12.9 2.0 2 0 0 2 2 2 0 Telomere-associated protein TERB2 ALMT PF11744.8 CDJ51133.1 - 5.4 5.7 8.0 6.5 5.5 8.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter MAJIN PF15077.6 CDJ51133.1 - 6 6.6 10.4 7.1 6.3 10.4 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein PBP_sp32 PF07222.12 CDJ51133.1 - 7.1 6.0 17.7 9 5.7 17.7 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Hamartin PF04388.12 CDJ51133.1 - 7.1 5.2 14.1 8.5 4.9 14.1 1.1 1 0 0 1 1 1 0 Hamartin protein Peptidase_S49_N PF08496.10 CDJ51133.1 - 8 6.5 10.7 33 4.5 8.7 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Conotoxin PF02950.17 CDJ51133.1 - 8.1 7.5 12.7 6.7 7.8 6.2 2.2 2 0 0 2 2 2 0 Conotoxin DUF2722 PF10846.8 CDJ51134.1 - 0.0011 18.0 14.2 0.0011 18.0 14.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Auxin_canalis PF05703.11 CDJ51134.1 - 0.0033 17.4 18.9 0.0033 17.4 18.9 1.7 1 1 1 2 2 2 1 Auxin canalisation RskA PF10099.9 CDJ51134.1 - 0.0068 16.7 13.2 0.0068 16.7 13.2 2.6 1 1 1 2 2 1 1 Anti-sigma-K factor rskA FAM91_C PF14648.6 CDJ51134.1 - 0.0071 15.2 3.1 0.0071 15.2 3.1 1.8 2 0 0 2 2 2 1 FAM91 C-terminus IHABP4_N PF16174.5 CDJ51134.1 - 0.014 16.0 26.4 0.091 13.4 8.0 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal ASC PF00858.24 CDJ51134.1 - 0.11 11.4 2.9 0.15 11.0 2.9 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel SpoIIP PF07454.11 CDJ51134.1 - 0.35 10.3 15.0 0.14 11.6 8.7 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CFIA_Pcf11 PF11526.8 CDJ51134.1 - 0.52 10.8 16.5 0.16 12.5 8.4 2.6 3 0 0 3 3 3 0 Subunit of cleavage factor IA Pcf11 EIIBC-GUT_N PF03612.14 CDJ51134.1 - 0.8 9.4 13.6 0.88 9.3 7.9 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Methyltransf_12 PF08242.12 CDJ51134.1 - 1.3 9.8 4.6 8.7 7.2 0.1 2.5 2 0 0 2 2 2 0 Methyltransferase domain Tau95_N PF17682.1 CDJ51134.1 - 2.3 8.4 15.6 0.78 9.9 0.1 2.3 2 0 0 2 2 2 0 Tau95 Triple barrel domain Folate_carrier PF01770.18 CDJ51134.1 - 5.7 5.6 16.3 0.035 12.9 5.8 1.9 1 1 1 2 2 2 0 Reduced folate carrier Coiled PF05710.12 CDJ51135.1 - 1.4 9.8 25.0 0.035 14.9 8.8 2.5 2 0 0 2 2 2 0 Coiled coil TAF PF02969.17 CDJ51136.1 - 0.018 15.2 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF1645 PF07816.11 CDJ51136.1 - 0.022 15.3 7.5 0.022 15.3 7.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Sporozoite_P67 PF05642.11 CDJ51136.1 - 0.024 12.8 1.8 0.079 11.0 0.1 2.2 2 1 0 2 2 2 0 Sporozoite P67 surface antigen DUF4692 PF15763.5 CDJ51136.1 - 0.17 12.3 6.3 0.35 11.3 6.3 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) EPL1 PF10513.9 CDJ51136.1 - 0.19 12.1 9.3 0.11 12.9 1.6 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like TFIIA PF03153.13 CDJ51136.1 - 0.2 11.6 36.8 1.1 9.2 6.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ51136.1 - 1.2 8.7 38.3 2.3 7.8 7.3 2.4 2 0 0 2 2 2 0 Spt20 family V_ATPase_I PF01496.19 CDJ51136.1 - 2.2 6.1 7.4 0.29 9.0 1.7 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family UPF0565 PF10561.9 CDJ51136.1 - 3 7.0 5.1 0.36 10.0 0.5 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 DUF2052 PF09747.9 CDJ51136.1 - 3 7.9 13.8 8.9 6.4 6.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF1151 PF06625.11 CDJ51136.1 - 4.4 7.3 22.6 0.23 11.4 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) DUF3371 PF11851.8 CDJ51136.1 - 5.6 8.1 21.9 1.4 10.0 11.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3371) LRR19-TM PF15176.6 CDJ51136.1 - 6.8 6.8 5.7 2.4 8.2 0.4 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain F-protein PF00469.20 CDJ51136.1 - 8.6 5.9 9.7 5.1 6.6 3.9 2.2 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef DUF3446 PF11928.8 CDJ51136.1 - 9.1 6.7 17.5 0.074 13.4 5.4 2.7 2 1 0 2 2 2 0 Early growth response N-terminal domain TAF6_C PF07571.13 CDJ51138.1 - 0.65 10.4 8.6 0.088 13.2 1.2 3.2 2 2 1 3 3 3 0 TAF6 C-terminal HEAT repeat domain SUIM_assoc PF16619.5 CDJ51139.1 - 0.0094 16.0 3.9 0.0094 16.0 3.9 12.7 7 4 1 8 8 8 3 Unstructured region C-term to UIM in Ataxin3 Guanylate_cyc PF00211.20 CDJ51143.1 - 4.7e-05 23.1 0.0 0.00013 21.7 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain SUIM_assoc PF16619.5 CDJ51143.1 - 0.018 15.1 6.6 0.042 13.9 6.6 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Virul_Fac PF10139.9 CDJ51143.1 - 0.03 12.6 4.7 0.042 12.1 4.7 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor MITF_TFEB_C_3_N PF15951.5 CDJ51143.1 - 0.031 14.9 5.8 0.031 14.9 5.8 2.3 2 1 1 3 3 3 0 MITF/TFEB/TFEC/TFE3 N-terminus TFIIA PF03153.13 CDJ51143.1 - 1.5 8.7 18.1 2.1 8.3 18.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ51143.1 - 9.5 5.7 17.5 29 4.1 17.5 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit TraG-D_C PF12696.7 CDJ51144.1 - 0.2 11.6 3.6 2.9 7.9 1.2 2.4 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG SPX PF03105.19 CDJ51144.1 - 0.28 11.1 2.3 0.31 10.9 2.3 1.2 1 0 0 1 1 1 0 SPX domain Guanylate_cyc PF00211.20 CDJ51146.1 - 7.5e-27 94.1 0.0 9.4e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain gpUL132 PF11359.8 CDJ51146.1 - 0.061 12.9 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Amidase PF01425.21 CDJ51147.1 - 1.9e-08 33.8 5.6 0.00034 19.7 4.1 2.8 2 0 0 2 2 2 2 Amidase EOS1 PF12326.8 CDJ51147.1 - 0.00062 19.7 1.0 3.2 7.7 0.0 3.0 3 1 0 3 3 3 2 N-glycosylation protein Presenilin PF01080.17 CDJ51147.1 - 2.4 6.8 30.5 0.022 13.5 19.1 2.6 3 0 0 3 3 3 0 Presenilin UPF0560 PF10577.9 CDJ51147.1 - 3.8 5.9 41.6 0.19 10.2 10.4 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0560 MecA PF05389.12 CDJ51147.1 - 5.8 6.5 21.8 0.47 10.0 3.1 3.0 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) SAC3_GANP PF03399.16 CDJ51148.1 - 1.7e-22 80.2 0.0 2.2e-12 47.0 0.2 6.0 6 2 0 6 6 6 2 SAC3/GANP family DUF2722 PF10846.8 CDJ51148.1 - 0.00018 20.6 1.1 0.00018 20.6 1.1 15.4 10 4 3 13 13 13 5 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ51148.1 - 0.0038 16.9 11.2 0.0038 16.9 11.2 14.7 10 3 1 11 11 11 6 Spt20 family TauE PF01925.19 CDJ51149.1 - 2.2e-07 30.8 8.0 3.1e-07 30.3 8.0 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE SpoIIP PF07454.11 CDJ51149.1 - 1.7e-05 24.4 5.9 2e-05 24.2 5.9 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Zip PF02535.22 CDJ51149.1 - 4.8e-05 22.7 0.0 6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter V_ATPase_I PF01496.19 CDJ51149.1 - 0.00022 19.3 8.7 0.00024 19.2 8.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF5308 PF17233.2 CDJ51149.1 - 0.0003 21.1 2.6 0.00038 20.7 2.6 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5308) CLN3 PF02487.17 CDJ51149.1 - 0.00049 19.3 4.7 0.00077 18.6 4.7 1.2 1 0 0 1 1 1 1 CLN3 protein SAPS PF04499.15 CDJ51149.1 - 0.00052 18.9 0.7 0.00055 18.9 0.7 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein PIP5K PF01504.18 CDJ51149.1 - 0.00094 18.5 5.0 0.0011 18.2 5.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SID-1_RNA_chan PF13965.6 CDJ51149.1 - 0.0012 17.3 0.8 0.0016 17.0 0.8 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Velvet PF11754.8 CDJ51149.1 - 0.0015 18.5 9.5 0.0019 18.2 9.5 1.1 1 0 0 1 1 1 1 Velvet factor DUF913 PF06025.12 CDJ51149.1 - 0.0027 16.8 3.2 0.0033 16.4 3.2 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Endostatin PF06482.11 CDJ51149.1 - 0.0033 16.9 8.4 0.0038 16.7 8.4 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Pex14_N PF04695.13 CDJ51149.1 - 0.0038 17.9 27.2 0.0038 17.9 27.2 1.5 2 0 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Serinc PF03348.15 CDJ51149.1 - 0.0057 15.6 3.0 0.0074 15.3 3.0 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) PepSY_TM PF03929.16 CDJ51149.1 - 0.0061 16.3 2.1 0.0061 16.3 2.1 1.8 2 0 0 2 2 1 1 PepSY-associated TM region Neur_chan_memb PF02932.16 CDJ51149.1 - 0.0081 16.2 7.4 0.011 15.8 7.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3464 PF11947.8 CDJ51149.1 - 0.014 15.2 11.5 0.029 14.1 11.5 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 OATP PF03137.20 CDJ51149.1 - 0.015 13.6 0.9 0.023 13.0 0.9 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S49_N PF08496.10 CDJ51149.1 - 0.015 15.3 8.2 0.033 14.2 8.2 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PA26 PF04636.13 CDJ51149.1 - 0.027 13.4 6.4 0.033 13.1 6.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF853 PF05872.12 CDJ51149.1 - 0.035 12.7 6.8 0.043 12.4 6.8 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) EPL1 PF10513.9 CDJ51149.1 - 0.037 14.4 13.3 0.055 13.9 13.3 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF1980 PF09323.10 CDJ51149.1 - 0.041 13.8 7.4 0.074 13.0 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Ureide_permease PF07168.11 CDJ51149.1 - 0.058 12.1 2.0 0.087 11.6 2.0 1.3 1 0 0 1 1 1 0 Ureide permease Anoctamin PF04547.12 CDJ51149.1 - 0.063 12.1 1.0 0.079 11.8 1.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel O-antigen_lig PF13425.6 CDJ51149.1 - 0.075 11.8 1.5 0.1 11.3 1.5 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF2464 PF10240.9 CDJ51149.1 - 0.077 12.5 6.0 0.1 12.2 6.0 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 Ndc1_Nup PF09531.10 CDJ51149.1 - 0.077 11.7 8.0 0.087 11.5 8.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Otopetrin PF03189.13 CDJ51149.1 - 0.084 11.7 3.2 0.11 11.3 3.2 1.2 1 0 0 1 1 1 0 Otopetrin PTPRCAP PF15713.5 CDJ51149.1 - 0.088 13.1 18.3 0.12 12.6 18.3 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated EOS1 PF12326.8 CDJ51149.1 - 0.1 12.5 4.6 0.17 11.8 4.6 1.4 1 0 0 1 1 1 0 N-glycosylation protein CPSF100_C PF13299.6 CDJ51149.1 - 0.1 12.8 11.3 0.16 12.2 11.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2561 PF10812.8 CDJ51149.1 - 0.12 12.4 0.6 0.21 11.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Connexin PF00029.19 CDJ51149.1 - 0.18 11.5 12.2 0.036 13.8 9.0 1.5 2 0 0 2 2 1 0 Connexin RR_TM4-6 PF06459.12 CDJ51149.1 - 0.21 11.4 19.0 0.28 11.0 19.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YABBY PF04690.13 CDJ51149.1 - 0.23 12.0 10.5 0.34 11.5 10.5 1.2 1 0 0 1 1 1 0 YABBY protein Med15 PF09606.10 CDJ51149.1 - 0.24 10.1 42.8 0.32 9.6 42.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CBP_BcsG PF11658.8 CDJ51149.1 - 0.27 9.6 9.2 0.35 9.2 9.2 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Lin-8 PF03353.15 CDJ51149.1 - 0.29 10.7 18.9 0.36 10.3 18.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pannexin_like PF12534.8 CDJ51149.1 - 0.34 9.9 9.3 0.46 9.5 9.3 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF4228 PF14009.6 CDJ51149.1 - 0.34 11.3 8.7 0.47 10.8 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) MMM1 PF10296.9 CDJ51149.1 - 0.36 9.8 7.3 0.48 9.4 7.3 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DUF4638 PF15472.6 CDJ51149.1 - 0.44 10.2 14.5 0.59 9.8 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) TERB2 PF15101.6 CDJ51149.1 - 0.55 10.3 24.1 1 9.3 24.1 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4746 PF15928.5 CDJ51149.1 - 0.56 9.6 12.7 0.74 9.2 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 CDJ51149.1 - 0.65 9.9 48.4 0.86 9.5 48.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Folate_carrier PF01770.18 CDJ51149.1 - 0.66 8.6 5.2 0.97 8.1 5.2 1.3 1 0 0 1 1 1 0 Reduced folate carrier HemX PF04375.14 CDJ51149.1 - 0.75 9.0 36.3 1 8.6 36.3 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Asparaginase_2 PF01112.18 CDJ51149.1 - 0.85 8.6 7.0 0.079 12.0 2.6 1.6 2 0 0 2 2 1 0 Asparaginase Dicty_REP PF05086.12 CDJ51149.1 - 1.2 7.1 7.7 1.4 6.8 7.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BORG_CEP PF14957.6 CDJ51149.1 - 1.2 10.3 10.0 1.7 9.8 10.0 1.2 1 0 0 1 1 1 0 Cdc42 effector Kei1 PF08552.11 CDJ51149.1 - 1.2 9.0 10.2 1.9 8.3 10.2 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2828 PF11443.8 CDJ51149.1 - 1.3 7.0 18.0 1.7 6.7 18.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MMR1 PF08505.10 CDJ51149.1 - 1.3 9.3 21.7 1.7 8.9 21.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CSG2 PF16965.5 CDJ51149.1 - 1.5 7.6 8.5 2.1 7.2 8.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator HCO3_cotransp PF00955.21 CDJ51149.1 - 1.7 7.4 4.4 2.2 7.0 4.4 1.1 1 0 0 1 1 1 0 HCO3- transporter family Baculo_PP31 PF05311.11 CDJ51149.1 - 2.6 7.5 15.8 3.8 6.9 15.8 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) MCM_bind PF09739.9 CDJ51149.1 - 2.9 6.2 16.9 3.7 5.9 16.9 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Spore_coat_CotO PF14153.6 CDJ51149.1 - 3.4 7.6 28.0 4.6 7.1 28.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SLC12 PF03522.15 CDJ51149.1 - 4 6.4 20.1 5.2 6.0 20.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 VIR_N PF15912.5 CDJ51149.1 - 4.1 6.9 10.6 5.6 6.5 10.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal FAM222A PF15258.6 CDJ51149.1 - 5 6.1 29.2 6.1 5.8 29.2 1.1 1 0 0 1 1 1 0 Protein family of FAM222A NARP1 PF12569.8 CDJ51149.1 - 5.1 5.9 21.7 6.7 5.5 21.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4192 PF13830.6 CDJ51149.1 - 5.2 7.0 8.2 7.1 6.6 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Presenilin PF01080.17 CDJ51149.1 - 6.1 5.5 28.3 9.1 4.9 28.3 1.2 1 0 0 1 1 1 0 Presenilin FAM91_C PF14648.6 CDJ51149.1 - 6.1 5.6 8.2 8.6 5.1 8.2 1.2 1 0 0 1 1 1 0 FAM91 C-terminus NPR3 PF03666.13 CDJ51149.1 - 6.5 5.4 20.1 8.7 5.0 20.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PAT1 PF09770.9 CDJ51149.1 - 6.9 4.8 34.4 8.7 4.5 34.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0560 PF10577.9 CDJ51149.1 - 8.3 4.8 30.4 11 4.4 30.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 EAL PF00563.20 CDJ51150.1 - 5.4 6.5 6.5 5.2 6.5 0.4 2.3 1 1 0 1 1 1 0 EAL domain DUF4227 PF14004.6 CDJ51151.1 - 0.17 11.9 0.0 0.89 9.6 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4227) DUF2828 PF11443.8 CDJ51151.1 - 0.5 8.4 27.1 0.18 9.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) FAM176 PF14851.6 CDJ51151.1 - 5.8 6.6 25.5 14 5.3 12.9 3.4 3 0 0 3 3 3 0 FAM176 family Hid1 PF12722.7 CDJ51151.1 - 6 4.9 38.3 46 1.9 39.5 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein TFIIA PF03153.13 CDJ51153.1 - 7 6.5 31.7 12 5.8 31.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Caldesmon PF02029.15 CDJ51154.1 - 0.0055 15.5 16.9 0.0074 15.1 16.9 1.1 1 0 0 1 1 1 1 Caldesmon Exonuc_VII_L PF02601.15 CDJ51154.1 - 0.9 9.0 16.0 1.7 8.1 16.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tetraspanin PF00335.20 CDJ51155.1 - 0.03 14.0 0.2 0.042 13.6 0.2 1.2 1 0 0 1 1 1 0 Tetraspanin family DNA_pack_N PF02500.15 CDJ51155.1 - 0.34 10.7 5.5 0.73 9.6 5.5 1.4 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus DUF3381 PF11861.8 CDJ51155.1 - 0.8 9.5 14.4 1.3 8.8 14.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Peptidase_M49 PF03571.15 CDJ51155.1 - 1 7.7 6.6 1.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M49 V_ATPase_I PF01496.19 CDJ51155.1 - 2.3 6.0 10.3 2.9 5.7 10.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 CDJ51155.1 - 3.4 8.1 14.1 4.6 7.7 14.1 1.1 1 0 0 1 1 1 0 AAA domain SUIM_assoc PF16619.5 CDJ51157.1 - 0.23 11.5 13.4 0.11 12.5 5.1 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ51159.1 - 0.00014 22.1 64.3 0.0016 18.5 25.3 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ51159.1 - 0.0086 15.6 15.6 0.01 15.3 4.4 2.2 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) DUF4820 PF16091.5 CDJ51159.1 - 0.033 13.6 17.5 0.044 13.2 1.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4820) MDM10 PF12519.8 CDJ51159.1 - 0.11 11.4 9.3 0.24 10.2 2.2 2.1 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 V_ATPase_I PF01496.19 CDJ51159.1 - 0.15 9.9 20.7 0.012 13.6 2.4 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family eIF-3_zeta PF05091.12 CDJ51159.1 - 0.32 9.9 26.2 0.82 8.6 12.8 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4471 PF14740.6 CDJ51159.1 - 0.44 9.7 11.8 0.29 10.3 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) ERO1 PF04137.15 CDJ51159.1 - 1 8.4 9.8 0.15 11.2 2.1 2.1 2 0 0 2 2 2 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Pal1 PF08316.11 CDJ51159.1 - 1.2 9.9 15.2 0.17 12.7 3.9 2.5 3 0 0 3 3 2 0 Pal1 cell morphology protein EIIBC-GUT_N PF03612.14 CDJ51159.1 - 2.3 7.9 22.3 0.26 11.0 7.3 2.7 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus SID-1_RNA_chan PF13965.6 CDJ51159.1 - 2.3 6.5 5.7 2.2 6.6 0.5 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Afi1 PF07792.12 CDJ51159.1 - 3.2 8.2 17.1 2.6 8.5 7.1 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF1980 PF09323.10 CDJ51159.1 - 3.4 7.5 13.9 5.5 6.9 6.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) TERB2 PF15101.6 CDJ51159.1 - 3.5 7.6 31.0 6.9 6.7 15.2 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 SAP18 PF06487.12 CDJ51159.1 - 4 7.6 11.0 4.4 7.5 4.5 2.4 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) DUF1764 PF08576.10 CDJ51159.1 - 4.3 8.3 19.8 0.32 11.9 5.2 2.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) EFTUD2 PF16004.5 CDJ51159.1 - 6.7 7.3 22.1 1.3 9.6 9.1 2.5 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus NPR1_interact PF15699.5 CDJ51159.1 - 8.1 7.1 21.9 3.5 8.3 9.6 2.6 2 0 0 2 2 2 0 NPR1 interacting DUF5523 PF17661.1 CDJ51159.1 - 8.1 6.0 21.6 1.6 8.3 9.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DUF4746 PF15928.5 CDJ51159.1 - 8.3 5.7 14.1 1.5 8.2 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF4179 PF13786.6 CDJ51160.1 - 0.011 16.2 4.4 1.6 9.2 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) RskA PF10099.9 CDJ51160.1 - 0.18 12.1 39.4 0.94 9.7 16.9 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA LYRIC PF15686.5 CDJ51160.1 - 1.4 8.4 10.2 2.1 7.8 10.2 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family RVT_1 PF00078.27 CDJ51162.1 - 0.041 13.4 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0240 PF06784.11 CDJ51164.1 - 0.045 13.8 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) SUZ PF12752.7 CDJ51164.1 - 1.1 10.1 7.5 0.29 11.9 0.9 3.6 2 0 0 2 2 2 0 SUZ domain Secretin_N_2 PF07655.13 CDJ51164.1 - 1.9 9.1 9.2 0.54 10.8 2.1 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain AAA_23 PF13476.6 CDJ51164.1 - 4.1 7.8 9.6 3.4 8.1 0.3 2.2 2 0 0 2 2 2 0 AAA domain HECT PF00632.25 CDJ51166.1 - 6.7e-52 176.9 0.0 1.2e-51 176.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CDJ51166.1 - 0.00035 20.7 0.0 0.0019 18.3 0.0 2.3 1 0 0 1 1 1 1 SPRY domain Spt20 PF12090.8 CDJ51166.1 - 0.00084 19.0 9.0 0.00084 19.0 9.0 23.2 19 4 2 21 21 21 1 Spt20 family Laminin_G_3 PF13385.6 CDJ51166.1 - 0.0013 18.9 0.0 0.028 14.5 0.0 2.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily TRAM_LAG1_CLN8 PF03798.16 CDJ51167.1 - 6e-07 29.4 0.0 1.6e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 TLC domain Med15 PF09606.10 CDJ51167.1 - 0.24 10.0 3.3 0.3 9.7 3.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HA2 PF04408.23 CDJ51168.1 - 8.4e-09 35.7 0.0 8.4e-09 35.7 0.0 4.9 5 1 0 5 5 5 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDJ51168.1 - 1.7e-07 31.5 0.0 2.7e-06 27.7 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDJ51168.1 - 0.0053 17.1 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold GREB1 PF15782.5 CDJ51168.1 - 0.021 12.0 20.9 0.046 10.9 20.9 1.6 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5473 PF17567.2 CDJ51168.1 - 0.26 11.6 4.0 0.21 11.9 0.2 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5473) HSP90 PF00183.18 CDJ51169.1 - 6.1e-106 355.4 0.0 2.4e-102 343.5 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CDJ51169.1 - 7.5e-11 42.0 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ51169.1 - 1.9e-09 38.0 0.0 4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HrpB2 PF09487.10 CDJ51172.1 - 0.083 13.3 1.4 0.11 12.9 1.4 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) RT_RNaseH_2 PF17919.1 CDJ51173.1 - 9.4e-17 60.9 0.0 1.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ51173.1 - 9.8e-10 38.3 0.0 1.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ51173.1 - 1.9e-06 28.1 0.0 4.8e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase GEP5 PF17053.5 CDJ51173.1 - 0.069 13.0 0.2 0.72 9.7 0.1 1.9 2 0 0 2 2 2 0 Genetic interactor of prohibitin 5 TerD PF02342.18 CDJ51175.1 - 2.7e-06 27.0 0.0 2.2e-05 24.0 0.0 2.3 3 0 0 3 3 3 1 TerD domain FIST_C PF10442.9 CDJ51175.1 - 0.1 12.5 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 FIST C domain PhoD PF09423.10 CDJ51176.1 - 2.2e-07 30.2 4.1 6.9e-06 25.3 4.1 2.2 1 1 0 1 1 1 1 PhoD-like phosphatase PWI PF01480.17 CDJ51178.1 - 1.4e-28 99.0 0.0 2.3e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 PWI domain PYC_OADA PF02436.18 CDJ51178.1 - 0.0093 15.7 0.1 0.015 15.1 0.1 1.3 1 1 0 1 1 1 1 Conserved carboxylase domain DIRP PF06584.13 CDJ51178.1 - 0.039 14.1 0.2 0.079 13.1 0.2 1.5 1 0 0 1 1 1 0 DIRP CALM_bind PF16025.5 CDJ51178.1 - 0.04 14.4 0.6 0.072 13.6 0.6 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Chromo PF00385.24 CDJ51179.1 - 0.00052 19.9 0.1 0.0012 18.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 CDJ51180.1 - 5.2e-16 58.8 1.9 5.7e-16 58.7 0.5 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ51180.1 - 1.4e-13 51.1 0.2 5.9e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 CDJ51180.1 - 1.7e-05 24.8 0.1 4.7e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ51180.1 - 0.0027 17.5 0.1 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like RskA PF10099.9 CDJ51181.1 - 0.0014 19.0 5.4 0.002 18.5 5.4 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ51181.1 - 0.0022 18.0 24.4 0.0026 17.9 24.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RPA43_OB PF17875.1 CDJ51181.1 - 0.0098 16.5 0.4 0.012 16.2 0.4 1.3 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I Presenilin PF01080.17 CDJ51181.1 - 0.75 8.5 4.0 0.79 8.4 4.0 1.1 1 0 0 1 1 1 0 Presenilin Activator_LAG-3 PF11498.8 CDJ51181.1 - 0.82 8.6 45.5 1.1 8.2 45.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3138 PF11336.8 CDJ51181.1 - 1.2 7.7 4.7 1.5 7.4 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF755 PF05501.11 CDJ51182.1 - 0.001 19.3 15.2 0.001 19.3 15.2 6.4 4 2 1 5 5 5 1 Domain of unknown function (DUF755) EMC3_TMCO1 PF01956.16 CDJ51182.1 - 0.49 10.1 1.7 0.85 9.3 1.7 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2489 PF10675.9 CDJ51182.1 - 3.8 7.5 15.3 2.7 7.9 4.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Kinase-PPPase PF03618.14 CDJ51183.1 - 0.19 11.5 2.5 0.28 10.9 2.5 1.3 1 0 0 1 1 1 0 Kinase/pyrophosphorylase CCSAP PF15748.5 CDJ51183.1 - 0.56 10.3 20.0 0.73 10.0 20.0 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PNISR PF15996.5 CDJ51183.1 - 1.5 9.1 25.9 2.2 8.5 25.9 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SLC12 PF03522.15 CDJ51183.1 - 2.1 7.3 18.6 2.7 6.9 18.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 CDJ51183.1 - 3.5 5.6 18.9 4.2 5.4 18.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Aft1_HRA PF11786.8 CDJ51183.1 - 4.4 7.7 5.4 9.3 6.7 5.4 2.0 1 1 0 1 1 1 0 Aft1 HRA domain CDC45 PF02724.14 CDJ51185.1 - 0.19 10.0 14.7 0.21 9.8 14.7 1.3 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 CDJ51185.1 - 0.24 8.5 32.1 0.28 8.3 32.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4551 PF15087.6 CDJ51185.1 - 0.77 8.5 19.6 0.91 8.3 19.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOG2 PF10428.9 CDJ51185.1 - 1.5 7.9 27.4 2.1 7.4 27.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.13 CDJ51185.1 - 1.6 8.3 27.5 2.2 7.8 27.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) O-antigen_lig PF13425.6 CDJ51185.1 - 1.9 7.2 8.3 3.2 6.4 8.3 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4045 PF13254.6 CDJ51185.1 - 2.6 7.6 30.6 3.6 7.1 30.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAPS PF04499.15 CDJ51185.1 - 2.7 6.7 17.1 3.7 6.2 17.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 CDJ51185.1 - 3.4 5.7 25.3 4 5.4 25.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Miga PF10265.9 CDJ51185.1 - 3.9 6.3 23.1 1.9 7.3 21.3 1.3 1 1 0 1 1 1 0 Mitoguardin DUF2126 PF09899.9 CDJ51185.1 - 4.7 5.1 15.1 6.3 4.7 15.1 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Hamartin PF04388.12 CDJ51185.1 - 6.9 5.2 25.3 8.8 4.8 25.3 1.2 1 0 0 1 1 1 0 Hamartin protein SpoIIP PF07454.11 CDJ51188.1 - 0.0026 17.3 4.9 0.0031 17.0 4.9 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) TctB PF07331.11 CDJ51188.1 - 0.0035 17.6 0.0 1.6 9.0 0.4 2.2 1 1 1 2 2 2 1 Tripartite tricarboxylate transporter TctB family Scs3p PF10261.9 CDJ51188.1 - 0.0039 16.7 0.1 0.0054 16.3 0.1 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM SARAF PF06682.12 CDJ51188.1 - 0.0046 16.7 1.2 0.0061 16.3 1.2 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis RskA PF10099.9 CDJ51188.1 - 0.0047 17.2 23.9 0.12 12.6 11.8 2.1 1 1 1 2 2 2 2 Anti-sigma-K factor rskA CobT PF06213.12 CDJ51188.1 - 0.0081 15.6 14.7 0.011 15.1 14.7 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT DUF4746 PF15928.5 CDJ51188.1 - 0.013 15.0 5.2 0.015 14.7 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Oxidored_q3 PF00499.20 CDJ51188.1 - 0.015 15.0 0.2 0.1 12.3 0.2 2.0 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DDHD PF02862.17 CDJ51188.1 - 0.016 15.4 1.8 0.018 15.2 1.8 1.2 1 0 0 1 1 1 0 DDHD domain Velvet PF11754.8 CDJ51188.1 - 0.022 14.7 3.5 0.026 14.5 3.5 1.2 1 0 0 1 1 1 0 Velvet factor SID-1_RNA_chan PF13965.6 CDJ51188.1 - 0.023 13.1 0.0 0.028 12.9 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF913 PF06025.12 CDJ51188.1 - 0.032 13.2 0.2 0.033 13.2 0.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1980 PF09323.10 CDJ51188.1 - 0.035 14.0 4.8 0.079 12.9 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Gaa1 PF04114.14 CDJ51188.1 - 0.037 13.0 0.5 0.06 12.4 0.5 1.4 1 1 0 1 1 1 0 Gaa1-like, GPI transamidase component DUF2828 PF11443.8 CDJ51188.1 - 0.044 11.9 8.3 0.05 11.7 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) BORG_CEP PF14957.6 CDJ51188.1 - 0.051 14.7 1.0 0.065 14.4 1.0 1.3 1 0 0 1 1 1 0 Cdc42 effector DUF3169 PF11368.8 CDJ51188.1 - 0.053 13.0 0.0 0.076 12.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) Trypan_PARP PF05887.11 CDJ51188.1 - 0.064 13.2 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NARP1 PF12569.8 CDJ51188.1 - 0.087 11.7 12.1 0.1 11.5 12.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2370 PF10176.9 CDJ51188.1 - 0.099 12.3 1.1 0.13 11.9 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) TFIIA PF03153.13 CDJ51188.1 - 0.14 12.2 24.4 0.16 11.9 24.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LAP1C PF05609.12 CDJ51188.1 - 0.14 11.3 11.0 0.17 10.9 11.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Connexin PF00029.19 CDJ51188.1 - 0.14 11.9 9.7 0.22 11.3 9.7 1.5 1 1 0 1 1 1 0 Connexin PIP5K PF01504.18 CDJ51188.1 - 0.14 11.3 6.0 0.2 10.8 6.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Neur_chan_memb PF02932.16 CDJ51188.1 - 0.15 12.1 4.0 0.2 11.7 4.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1345 PF07077.11 CDJ51188.1 - 0.53 10.0 1.6 1.6 8.4 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) Afi1 PF07792.12 CDJ51188.1 - 0.55 10.7 10.3 0.34 11.4 8.5 1.5 2 0 0 2 2 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Tim54 PF11711.8 CDJ51188.1 - 0.57 8.9 9.1 0.7 8.6 9.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.6 CDJ51188.1 - 0.59 9.8 10.6 0.68 9.6 9.4 1.6 1 1 0 1 1 1 0 FAM176 family ALMT PF11744.8 CDJ51188.1 - 0.67 8.7 3.7 0.74 8.6 3.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter ETRAMP PF09716.10 CDJ51188.1 - 0.72 10.0 0.0 0.72 10.0 0.0 2.7 2 2 0 2 2 1 0 Malarial early transcribed membrane protein (ETRAMP) CLN3 PF02487.17 CDJ51188.1 - 0.81 8.7 9.5 0.43 9.6 7.8 1.4 1 1 0 1 1 1 0 CLN3 protein DUF4366 PF14283.6 CDJ51188.1 - 0.89 9.6 5.8 1.7 8.7 4.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) V_ATPase_I PF01496.19 CDJ51188.1 - 1 7.2 14.1 0.62 7.9 12.6 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 CDJ51188.1 - 1.1 8.2 9.0 1.4 7.8 9.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 TAF4 PF05236.14 CDJ51188.1 - 1.2 8.8 18.5 1.8 8.2 18.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CDC45 PF02724.14 CDJ51188.1 - 1.4 7.2 12.5 1.6 6.9 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5523 PF17661.1 CDJ51188.1 - 1.5 8.4 20.7 1.9 8.1 20.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) XRN_M PF17846.1 CDJ51188.1 - 1.8 7.5 7.1 2.2 7.2 7.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Pap_E4 PF02711.14 CDJ51188.1 - 2 9.5 12.3 4.2 8.4 12.3 1.5 1 0 0 1 1 1 0 E4 protein Pex14_N PF04695.13 CDJ51188.1 - 2 9.0 16.0 3.8 8.1 16.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 CDJ51188.1 - 2.1 6.5 18.5 2.5 6.3 18.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.6 CDJ51188.1 - 2.4 8.1 7.3 3.1 7.8 7.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_S64 PF08192.11 CDJ51188.1 - 5.9 5.3 7.1 6.6 5.1 7.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 CrgA PF06781.12 CDJ51188.1 - 6.3 6.9 4.9 11 6.1 3.5 2.1 1 1 1 2 2 2 0 Cell division protein CrgA MDM10 PF12519.8 CDJ51188.1 - 9.1 5.0 9.9 12 4.7 9.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 HEAT_EZ PF13513.6 CDJ51191.1 - 1.9e-09 37.8 14.1 7.7e-05 23.1 0.0 13.5 11 4 3 14 14 14 5 HEAT-like repeat HEAT PF02985.22 CDJ51191.1 - 7.1e-06 25.8 19.3 0.2 12.0 0.0 7.9 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 CDJ51191.1 - 0.00021 21.4 4.0 0.31 11.1 0.1 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CDJ51191.1 - 0.0014 18.6 7.8 3.4 7.8 1.2 4.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CDJ51191.1 - 0.013 16.1 0.2 0.37 11.4 0.0 3.3 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Importin_rep_4 PF18808.1 CDJ51191.1 - 5 7.5 11.5 0.55 10.5 4.6 2.9 3 0 0 3 3 3 0 Importin repeat DUF572 PF04502.13 CDJ51191.1 - 9.9 5.7 34.1 0.66 9.5 25.9 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF572) SpoIIE PF07228.12 CDJ51192.1 - 0.003 17.5 0.0 0.003 17.5 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) DUF2722 PF10846.8 CDJ51192.1 - 0.01 14.8 19.6 0.38 9.6 14.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF2298 PF10060.9 CDJ51192.1 - 0.02 13.6 5.2 0.83 8.3 0.9 2.3 2 0 0 2 2 2 0 Uncharacterized membrane protein (DUF2298) DUF4131 PF13567.6 CDJ51192.1 - 0.15 11.7 8.1 1.2 8.7 1.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) MMM1 PF10296.9 CDJ51192.1 - 0.21 10.6 3.3 0.099 11.7 0.4 1.8 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Lin-8 PF03353.15 CDJ51192.1 - 0.21 11.1 11.9 0.24 10.9 8.8 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist EOS1 PF12326.8 CDJ51192.1 - 0.32 10.9 6.0 4 7.4 1.4 2.3 2 0 0 2 2 2 0 N-glycosylation protein Cwf_Cwc_15 PF04889.12 CDJ51192.1 - 1.6 8.4 13.9 9.6 5.8 0.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 CDJ51192.1 - 1.8 8.5 56.9 0.42 10.6 38.4 2.2 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit CBP_BcsG PF11658.8 CDJ51192.1 - 2.5 6.4 8.3 0.37 9.1 3.4 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG MASE2 PF05230.11 CDJ51193.1 - 0.11 12.6 2.8 0.35 11.0 2.8 1.9 1 1 0 1 1 1 0 MASE2 domain DUF1635 PF07795.11 CDJ51193.1 - 0.12 12.2 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) SR-25 PF10500.9 CDJ51193.1 - 1.5 8.4 6.7 0.94 9.0 4.3 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ51195.1 - 6.9e-08 31.9 26.3 0.00015 20.8 7.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ51195.1 - 0.0011 18.6 14.5 0.0011 18.6 14.5 2.2 2 0 0 2 2 2 1 Spt20 family Suf PF05843.14 CDJ51195.1 - 0.0016 18.5 18.0 0.026 14.5 1.4 2.3 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) EPL1 PF10513.9 CDJ51195.1 - 0.0094 16.3 12.2 0.32 11.4 2.4 2.5 2 0 0 2 2 2 2 Enhancer of polycomb-like MecA PF05389.12 CDJ51195.1 - 0.033 13.8 6.8 0.89 9.1 0.5 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) FAM176 PF14851.6 CDJ51195.1 - 0.06 13.0 4.6 1.4 8.5 0.8 2.3 2 0 0 2 2 2 0 FAM176 family Band_3_cyto PF07565.13 CDJ51195.1 - 0.062 13.1 9.4 1 9.1 1.0 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain HNOBA PF07701.14 CDJ51195.1 - 0.07 12.5 6.5 1.5 8.2 0.3 2.3 2 0 0 2 2 2 0 Heme NO binding associated DUF572 PF04502.13 CDJ51195.1 - 0.071 12.7 8.9 0.64 9.6 0.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4770 PF15994.5 CDJ51195.1 - 0.11 12.8 14.1 0.46 10.7 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) MMR1 PF08505.10 CDJ51195.1 - 0.16 12.2 15.5 1.4 9.2 3.4 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF702 PF05142.12 CDJ51195.1 - 0.17 12.3 17.2 1.5 9.3 4.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Apc15p PF05841.11 CDJ51195.1 - 0.19 12.5 19.7 1.9 9.3 7.3 2.6 2 0 0 2 2 2 0 Apc15p protein SpoIIP PF07454.11 CDJ51195.1 - 0.24 10.8 12.8 0.85 9.0 2.7 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) LIM_bind PF01803.16 CDJ51195.1 - 0.26 10.8 11.7 0.97 8.9 1.3 2.3 2 0 0 2 2 2 0 LIM-domain binding protein RR_TM4-6 PF06459.12 CDJ51195.1 - 0.33 10.7 12.6 0.26 11.1 0.6 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Eapp_C PF10238.9 CDJ51195.1 - 0.35 10.9 13.1 1.6 8.8 3.0 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein EOS1 PF12326.8 CDJ51195.1 - 0.36 10.7 6.3 0.68 9.8 0.1 2.2 2 0 0 2 2 2 0 N-glycosylation protein RPA43_OB PF17875.1 CDJ51195.1 - 0.37 11.4 7.5 4.1 8.0 0.6 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I EIF4E-T PF10477.9 CDJ51195.1 - 0.54 9.0 22.0 0.076 11.8 1.5 2.2 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF3464 PF11947.8 CDJ51195.1 - 0.62 9.8 15.2 0.66 9.7 2.1 2.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF2126 PF09899.9 CDJ51195.1 - 0.63 8.1 6.2 0.95 7.5 0.3 2.1 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) SLC12 PF03522.15 CDJ51195.1 - 0.72 8.8 11.4 1.9 7.4 2.3 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Maf1 PF09174.10 CDJ51195.1 - 1.5 9.0 8.5 6.8 6.8 1.5 2.2 2 0 0 2 2 2 0 Maf1 regulator Rxt3 PF08642.10 CDJ51195.1 - 1.7 9.4 8.8 6.9 7.5 0.6 2.5 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 FAM60A PF15396.6 CDJ51195.1 - 2 8.3 8.8 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF775 PF05603.12 CDJ51195.1 - 2.1 7.8 22.3 0.65 9.5 5.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF775) DUF4834 PF16118.5 CDJ51195.1 - 2.2 9.3 26.4 3.4 8.7 8.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Lin-8 PF03353.15 CDJ51195.1 - 2.9 7.4 21.7 1.3 8.5 4.0 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist ALMT PF11744.8 CDJ51195.1 - 3 6.6 7.6 6.6 5.4 0.7 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter MMU163 PF17119.5 CDJ51195.1 - 3 6.9 7.2 7 5.7 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis EIIBC-GUT_N PF03612.14 CDJ51195.1 - 3.1 7.5 14.8 6.2 6.5 2.4 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus PRP1_N PF06424.12 CDJ51195.1 - 3.3 8.1 19.4 0.26 11.7 0.6 3.2 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal Pex14_N PF04695.13 CDJ51195.1 - 3.5 8.3 49.3 0.14 12.8 17.2 3.2 2 1 1 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4638 PF15472.6 CDJ51195.1 - 3.6 7.3 13.7 4.4 7.0 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) DUF1266 PF06889.11 CDJ51195.1 - 4.3 7.3 13.1 1.4 8.9 0.8 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1266) TERB2 PF15101.6 CDJ51195.1 - 5 7.1 27.0 5 7.1 9.2 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Connexin PF00029.19 CDJ51195.1 - 6.7 6.4 11.3 2.1 8.1 0.4 2.1 2 0 0 2 2 2 0 Connexin DUF1764 PF08576.10 CDJ51195.1 - 8.8 7.3 15.3 6.3 7.8 1.7 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) ATAD4 PF15321.6 CDJ51195.1 - 9.3 7.7 15.0 20 6.6 3.9 2.5 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 BORG_CEP PF14957.6 CDJ51195.1 - 9.5 7.4 14.5 16 6.6 1.3 2.6 2 1 0 2 2 2 0 Cdc42 effector Peptidase_S49_N PF08496.10 CDJ51196.1 - 0.13 12.3 10.2 0.15 12.1 10.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Hydin_ADK PF17213.3 CDJ51196.1 - 0.25 11.6 15.4 0.28 11.4 15.4 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain TYW3 PF02676.14 CDJ51196.1 - 0.49 9.7 5.3 0.55 9.6 5.3 1.1 1 0 0 1 1 1 0 Methyltransferase TYW3 DUF4569 PF15133.6 CDJ51196.1 - 0.54 9.9 14.9 0.6 9.8 14.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) BAF1_ABF1 PF04684.13 CDJ51196.1 - 0.58 9.1 13.4 0.71 8.9 13.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FAM60A PF15396.6 CDJ51196.1 - 0.64 10.0 8.3 0.72 9.8 8.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A OATP PF03137.20 CDJ51196.1 - 0.65 8.2 6.7 0.74 8.0 6.7 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2981 PF11200.8 CDJ51196.1 - 0.69 9.6 4.5 0.72 9.6 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Serinc PF03348.15 CDJ51196.1 - 0.71 8.7 7.7 0.7 8.8 7.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1980 PF09323.10 CDJ51196.1 - 0.84 9.5 12.4 1 9.2 12.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Connexin PF00029.19 CDJ51196.1 - 0.88 9.3 9.8 1 9.1 9.8 1.1 1 0 0 1 1 1 0 Connexin DUF2828 PF11443.8 CDJ51196.1 - 1.3 7.0 13.1 1.3 7.0 13.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Baculo_PP31 PF05311.11 CDJ51196.1 - 1.5 8.3 13.5 1.6 8.1 13.5 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Neur_chan_memb PF02932.16 CDJ51196.1 - 1.6 8.8 10.2 1.7 8.7 10.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.13 CDJ51196.1 - 1.6 9.4 25.8 2.1 9.0 25.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.6 CDJ51196.1 - 1.6 8.4 7.0 2 8.1 7.0 1.2 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.8 CDJ51196.1 - 1.8 7.3 11.8 1.9 7.2 11.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ALGX PF16822.5 CDJ51196.1 - 1.8 8.2 19.2 2.2 7.9 19.2 1.0 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX DUF913 PF06025.12 CDJ51196.1 - 1.8 7.5 9.4 1.9 7.4 9.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFIIA PF03153.13 CDJ51196.1 - 1.9 8.4 39.1 2.3 8.1 39.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5427 PF10310.9 CDJ51196.1 - 2.1 7.2 18.0 2.4 7.0 18.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4228 PF14009.6 CDJ51196.1 - 3.4 8.0 10.3 3.5 8.0 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) YABBY PF04690.13 CDJ51196.1 - 3.4 8.2 10.7 3.9 8.0 10.7 1.1 1 0 0 1 1 1 0 YABBY protein PAT1 PF09770.9 CDJ51196.1 - 3.5 5.8 26.7 4.1 5.6 26.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ureide_permease PF07168.11 CDJ51196.1 - 3.6 6.3 4.7 4.1 6.0 4.7 1.2 1 0 0 1 1 1 0 Ureide permease RR_TM4-6 PF06459.12 CDJ51196.1 - 3.6 7.3 16.0 3.8 7.3 16.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_U57 PF05582.12 CDJ51196.1 - 3.7 6.7 10.2 4 6.6 10.2 1.0 1 0 0 1 1 1 0 YabG peptidase U57 CDC45 PF02724.14 CDJ51196.1 - 3.8 5.7 12.6 3.9 5.6 12.6 1.0 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 CDJ51196.1 - 4 6.8 14.9 4.5 6.6 14.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TERB2 PF15101.6 CDJ51196.1 - 4 7.4 18.8 5.1 7.1 18.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Med15 PF09606.10 CDJ51196.1 - 4.2 5.9 39.2 5.3 5.6 39.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ctr PF04145.15 CDJ51196.1 - 4.2 8.0 7.4 5.7 7.6 7.4 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Gti1_Pac2 PF09729.9 CDJ51196.1 - 4.4 7.4 11.0 5 7.2 11.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 CDJ51196.1 - 4.4 6.2 14.2 4.5 6.2 14.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Otopetrin PF03189.13 CDJ51196.1 - 4.5 6.0 8.8 4.7 5.9 8.8 1.0 1 0 0 1 1 1 0 Otopetrin PIP5K PF01504.18 CDJ51196.1 - 5.8 6.1 13.3 7 5.8 13.3 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CLN3 PF02487.17 CDJ51196.1 - 6.8 5.6 10.5 7.7 5.5 10.5 1.0 1 0 0 1 1 1 0 CLN3 protein DUF1151 PF06625.11 CDJ51196.1 - 7.1 6.6 24.6 9.2 6.3 24.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Band_3_cyto PF07565.13 CDJ51196.1 - 7.5 6.3 13.4 8.9 6.0 13.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Sec62 PF03839.16 CDJ51196.1 - 7.8 5.9 10.1 8.8 5.8 10.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Pannexin_like PF12534.8 CDJ51196.1 - 8.1 5.4 10.7 9.6 5.2 10.7 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Presenilin PF01080.17 CDJ51196.1 - 8.3 5.1 21.1 8.5 5.0 21.1 1.0 1 0 0 1 1 1 0 Presenilin Paf1 PF03985.13 CDJ51196.1 - 8.8 5.2 17.3 9.8 5.0 17.3 1.0 1 0 0 1 1 1 0 Paf1 Hid1 PF12722.7 CDJ51196.1 - 8.8 4.3 15.0 9.5 4.2 15.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Membralin PF09746.9 CDJ51196.1 - 9.7 5.1 8.4 11 4.9 8.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein DDRGK PF09756.9 CDJ51196.1 - 9.8 5.7 21.4 12 5.4 21.4 1.1 1 0 0 1 1 1 0 DDRGK domain RskA PF10099.9 CDJ51197.1 - 5.9e-07 29.9 8.2 5.9e-07 29.9 8.2 4.8 2 2 0 2 2 2 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ51197.1 - 0.0064 16.1 18.6 0.0064 16.1 18.6 3.4 1 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein PRC2_HTH_1 PF18118.1 CDJ51198.1 - 0.81 10.5 17.7 0.15 12.8 2.7 3.1 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain APP_N PF02177.16 CDJ51198.1 - 0.95 9.9 7.9 2.3 8.6 0.2 2.7 2 1 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding Sulf_transp PF04143.14 CDJ51198.1 - 5.2 6.5 6.1 1.5 8.3 1.3 2.0 1 1 1 2 2 2 0 Sulphur transport DNA_pol_D_N PF18018.1 CDJ51199.1 - 2.3e-22 79.5 0.0 8.8e-22 77.6 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 CDJ51199.1 - 5.4e-19 68.4 0.0 8.7e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B RskA PF10099.9 CDJ51199.1 - 0.86 9.9 53.8 0.77 10.0 14.0 3.4 3 0 0 3 3 3 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ51200.1 - 0.12 12.4 55.0 0.14 12.1 55.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LMBR1 PF04791.16 CDJ51200.1 - 0.57 9.0 3.2 0.53 9.1 3.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Hamartin PF04388.12 CDJ51200.1 - 1 7.9 15.9 1.4 7.5 15.9 1.2 1 0 0 1 1 1 0 Hamartin protein Rrn6 PF10214.9 CDJ51200.1 - 2.2 6.7 13.4 3 6.2 13.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Endomucin PF07010.12 CDJ51200.1 - 8.2 6.3 20.9 14 5.6 20.9 1.4 1 0 0 1 1 1 0 Endomucin Med15 PF09606.10 CDJ51200.1 - 9.4 4.8 43.4 16 4.1 43.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Secretin_N_2 PF07655.13 CDJ51201.1 - 7.6e-05 23.2 1.8 0.00012 22.5 1.8 1.3 1 0 0 1 1 1 1 Secretin N-terminal domain AF-4 PF05110.13 CDJ51201.1 - 0.014 13.5 4.8 0.019 13.1 4.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2967 PF11179.8 CDJ51201.1 - 0.11 10.5 5.7 0.22 9.6 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) FliD_N PF02465.18 CDJ51201.1 - 0.23 12.2 0.4 0.23 12.2 0.4 2.4 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus TFIIA PF03153.13 CDJ51201.1 - 0.47 10.4 6.7 0.84 9.6 6.8 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ51201.1 - 5.3 7.2 22.1 4.6 7.4 10.4 3.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Lin-8 PF03353.15 CDJ51202.1 - 0.0058 16.2 24.5 0.0058 16.2 24.5 4.6 3 1 1 4 4 4 1 Ras-mediated vulval-induction antagonist DUF755 PF05501.11 CDJ51202.1 - 0.014 15.7 15.4 0.014 15.7 15.4 8.0 6 2 1 7 7 7 0 Domain of unknown function (DUF755) Abhydrolase_6 PF12697.7 CDJ51203.1 - 7.1e-07 30.1 14.9 1.3e-06 29.1 14.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ51203.1 - 8.7e-05 22.3 0.0 0.2 11.2 0.0 2.7 2 2 0 2 2 2 2 alpha/beta hydrolase fold TFIIA PF03153.13 CDJ51203.1 - 0.0014 18.7 5.0 0.0017 18.4 5.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ51203.1 - 0.0037 16.3 1.5 0.0045 16.0 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Ndr PF03096.14 CDJ51203.1 - 0.0049 15.6 0.0 1.2 7.7 0.0 2.1 2 0 0 2 2 2 2 Ndr family Thioesterase PF00975.20 CDJ51203.1 - 0.013 15.7 3.3 0.022 14.9 3.3 1.4 1 1 0 1 1 1 0 Thioesterase domain Spt20 PF12090.8 CDJ51203.1 - 0.022 14.4 10.0 0.032 13.8 10.0 1.2 1 0 0 1 1 1 0 Spt20 family Hydrolase_4 PF12146.8 CDJ51203.1 - 0.029 13.7 0.1 1.8 7.7 0.0 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 DUF1749 PF08538.10 CDJ51203.1 - 0.048 12.7 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.13 CDJ51203.1 - 0.1 12.4 0.7 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 CDJ51203.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Thioredoxin_16 PF18569.1 CDJ51203.1 - 0.24 11.5 1.3 0.81 9.9 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Herpes_TAF50 PF03326.13 CDJ51203.1 - 1.9 7.0 12.0 2.7 6.5 12.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Activator_LAG-3 PF11498.8 CDJ51203.1 - 3.4 6.5 18.0 4.9 6.0 18.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SR-25 PF10500.9 CDJ51204.1 - 0.00054 19.7 8.1 0.0008 19.1 8.1 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4054 PF13262.6 CDJ51204.1 - 0.16 12.0 4.3 0.31 11.1 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) CCDC106 PF15794.5 CDJ51204.1 - 1 9.0 5.2 1.4 8.6 5.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF2722 PF10846.8 CDJ51205.1 - 0.00012 21.2 20.2 0.00012 21.2 20.2 4.8 5 0 0 5 5 5 2 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ51205.1 - 0.00067 20.6 3.3 0.00067 20.6 3.3 5.4 4 2 0 4 4 4 2 Domain of unknown function (DUF4834) Sin_N PF04801.13 CDJ51206.1 - 0.0087 15.3 17.6 0.0097 15.2 17.6 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region Lin-8 PF03353.15 CDJ51206.1 - 0.15 11.6 11.2 0.17 11.4 11.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ51206.1 - 0.15 12.0 35.4 0.18 11.7 35.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CSRNP_N PF16019.5 CDJ51206.1 - 0.17 11.8 9.3 0.19 11.6 9.3 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus UPF0560 PF10577.9 CDJ51206.1 - 0.23 9.9 14.5 0.22 10.0 14.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3292 PF11696.8 CDJ51206.1 - 1.4 7.2 14.4 1.7 6.9 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Band_3_cyto PF07565.13 CDJ51206.1 - 1.5 8.6 9.3 1.7 8.4 9.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PepSY_TM_like_2 PF16357.5 CDJ51206.1 - 1.8 8.5 6.3 2.2 8.2 6.3 1.2 1 0 0 1 1 1 0 Putative PepSY_TM-like PAT1 PF09770.9 CDJ51206.1 - 2.3 6.4 23.6 2.5 6.3 23.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nop53 PF07767.11 CDJ51206.1 - 2.4 7.4 19.1 3.2 7.1 19.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SLC12 PF03522.15 CDJ51206.1 - 2.8 6.9 11.7 3.1 6.7 11.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Membralin PF09746.9 CDJ51206.1 - 3.3 6.6 6.5 3.8 6.4 6.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein IER PF05760.12 CDJ51206.1 - 4.2 7.6 27.6 4.8 7.4 27.6 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) Connexin PF00029.19 CDJ51206.1 - 4.3 7.0 6.8 5.4 6.7 6.8 1.2 1 0 0 1 1 1 0 Connexin Hid1 PF12722.7 CDJ51206.1 - 4.5 5.3 11.2 4.8 5.2 11.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OATP PF03137.20 CDJ51206.1 - 4.6 5.4 5.7 5.6 5.1 5.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3112 PF11309.8 CDJ51206.1 - 4.9 6.6 5.4 6.6 6.1 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) SRP-alpha_N PF04086.13 CDJ51206.1 - 5.2 6.9 16.8 6.4 6.6 16.8 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Sec62 PF03839.16 CDJ51206.1 - 6.4 6.2 9.1 7.6 6.0 9.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 CSG2 PF16965.5 CDJ51206.1 - 6.9 5.5 5.1 8.2 5.3 5.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4638 PF15472.6 CDJ51206.1 - 7.1 6.3 11.4 8.7 6.0 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) ALMT PF11744.8 CDJ51206.1 - 7.4 5.3 9.0 8.7 5.0 9.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MDM10 PF12519.8 CDJ51206.1 - 7.8 5.2 9.7 8.5 5.1 9.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF966 PF06136.13 CDJ51206.1 - 8.3 6.0 15.0 9.6 5.8 15.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) EOS1 PF12326.8 CDJ51206.1 - 9.2 6.2 7.0 14 5.5 7.0 1.4 1 0 0 1 1 1 0 N-glycosylation protein Zip PF02535.22 CDJ51206.1 - 9.8 5.3 6.2 11 5.1 6.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Plasmodium_Vir PF05795.11 CDJ51206.1 - 9.9 5.5 7.3 11 5.3 7.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mito_fiss_reg PF05308.11 CDJ51207.1 - 0.13 12.3 7.7 0.17 12.0 7.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3309 PF11752.8 CDJ51207.1 - 0.46 10.6 10.3 2 8.5 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF3328 PF11807.8 CDJ51207.1 - 4.2 7.1 7.0 20 4.9 7.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) SR-25 PF10500.9 CDJ51208.1 - 0.0033 17.1 23.7 0.0033 17.1 23.7 8.1 5 1 2 8 8 8 4 Nuclear RNA-splicing-associated protein Amidohydro_2 PF04909.14 CDJ51209.1 - 0.82 9.4 11.8 0.92 9.2 11.8 1.1 1 0 0 1 1 1 0 Amidohydrolase OATP PF03137.20 CDJ51210.1 - 0.00087 17.7 1.1 0.001 17.5 1.1 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family CobT PF06213.12 CDJ51210.1 - 0.0011 18.4 9.4 0.0014 18.1 9.4 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CLN3 PF02487.17 CDJ51210.1 - 0.0014 17.8 3.7 0.0016 17.5 3.7 1.2 1 0 0 1 1 1 1 CLN3 protein Connexin PF00029.19 CDJ51210.1 - 0.0014 18.4 1.8 0.0017 18.2 1.8 1.2 1 0 0 1 1 1 1 Connexin DUF1980 PF09323.10 CDJ51210.1 - 0.0016 18.4 1.5 0.0022 18.0 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) SID-1_RNA_chan PF13965.6 CDJ51210.1 - 0.0018 16.8 3.2 0.0021 16.6 3.2 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 CBP_BcsG PF11658.8 CDJ51210.1 - 0.002 16.6 5.7 0.0022 16.5 5.7 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG Serinc PF03348.15 CDJ51210.1 - 0.0023 17.0 3.4 0.0028 16.7 3.4 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) V_ATPase_I PF01496.19 CDJ51210.1 - 0.0023 15.9 6.4 0.0025 15.8 6.4 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ51210.1 - 0.0026 17.8 26.2 0.0029 17.7 26.2 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FHIPEP PF00771.20 CDJ51210.1 - 0.0032 16.0 7.8 0.0038 15.8 7.8 1.0 1 0 0 1 1 1 1 FHIPEP family DUF4834 PF16118.5 CDJ51210.1 - 0.0039 18.1 13.9 0.0072 17.3 13.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4834) MecA PF05389.12 CDJ51210.1 - 0.0041 16.8 2.9 0.0041 16.8 2.9 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) RskA PF10099.9 CDJ51210.1 - 0.0057 17.0 19.6 0.019 15.3 19.6 1.9 1 1 0 1 1 1 1 Anti-sigma-K factor rskA DDHD PF02862.17 CDJ51210.1 - 0.0084 16.3 5.2 0.0086 16.3 5.2 1.1 1 0 0 1 1 1 1 DDHD domain PIP5K PF01504.18 CDJ51210.1 - 0.0087 15.3 2.5 0.0092 15.2 2.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase eIF-3_zeta PF05091.12 CDJ51210.1 - 0.0087 15.1 10.2 0.0093 15.0 10.2 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.14 CDJ51210.1 - 0.009 14.4 3.5 0.01 14.2 3.5 1.1 1 0 0 1 1 1 1 CDC45-like protein PigN PF04987.14 CDJ51210.1 - 0.011 14.7 6.6 0.017 14.0 6.5 1.3 1 1 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) CPSF100_C PF13299.6 CDJ51210.1 - 0.011 15.9 4.0 0.013 15.7 4.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AI-2E_transport PF01594.16 CDJ51210.1 - 0.013 14.7 2.6 0.015 14.5 2.6 1.0 1 0 0 1 1 1 0 AI-2E family transporter FAM91_C PF14648.6 CDJ51210.1 - 0.014 14.3 2.5 0.013 14.3 2.5 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Peptidase_S49_N PF08496.10 CDJ51210.1 - 0.014 15.5 8.7 0.02 15.0 8.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EIIBC-GUT_N PF03612.14 CDJ51210.1 - 0.014 15.1 6.3 0.016 15.0 6.3 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus BAF1_ABF1 PF04684.13 CDJ51210.1 - 0.015 14.4 7.3 0.02 14.0 7.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CCDC53 PF10152.9 CDJ51210.1 - 0.017 15.5 6.7 0.018 15.4 6.7 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2347 PF09804.9 CDJ51210.1 - 0.022 14.4 1.5 0.028 14.0 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) EOS1 PF12326.8 CDJ51210.1 - 0.024 14.6 3.4 0.03 14.2 3.4 1.2 1 0 0 1 1 1 0 N-glycosylation protein Band_3_cyto PF07565.13 CDJ51210.1 - 0.025 14.4 5.0 0.025 14.4 5.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Glyco_transf_8 PF01501.20 CDJ51210.1 - 0.025 14.1 0.9 0.026 14.1 0.9 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 8 Kei1 PF08552.11 CDJ51210.1 - 0.031 14.2 5.5 0.04 13.8 5.5 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 PAT1 PF09770.9 CDJ51210.1 - 0.034 12.5 14.6 0.036 12.4 14.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peroxin-13_N PF04088.13 CDJ51210.1 - 0.035 14.4 6.0 0.031 14.5 5.2 1.4 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Neur_chan_memb PF02932.16 CDJ51210.1 - 0.036 14.1 3.3 0.04 14.0 3.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NEMP PF10225.9 CDJ51210.1 - 0.04 13.6 6.1 0.048 13.3 6.1 1.2 1 0 0 1 1 1 0 NEMP family Rxt3 PF08642.10 CDJ51210.1 - 0.043 14.6 2.4 0.058 14.2 2.4 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 AIF_C PF14721.6 CDJ51210.1 - 0.052 13.9 5.6 0.067 13.6 5.6 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CSG2 PF16965.5 CDJ51210.1 - 0.066 12.2 2.1 0.074 12.0 2.1 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator RP853 PF17542.2 CDJ51210.1 - 0.089 11.9 0.2 0.1 11.7 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 U1snRNP70_N PF12220.8 CDJ51210.1 - 0.09 13.4 9.0 0.12 13.0 9.0 1.2 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SpoIIP PF07454.11 CDJ51210.1 - 0.091 12.2 10.3 0.11 12.0 10.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) HemX PF04375.14 CDJ51210.1 - 0.092 12.0 28.8 0.12 11.7 28.8 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Peptidase_S15 PF02129.18 CDJ51210.1 - 0.099 12.2 9.4 0.13 11.9 9.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Na_trans_assoc PF06512.13 CDJ51210.1 - 0.12 12.7 7.8 0.17 12.2 7.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Wzy_C PF04932.15 CDJ51210.1 - 0.13 11.8 0.1 0.23 11.1 0.1 1.5 1 1 0 1 1 1 0 O-Antigen ligase ALMT PF11744.8 CDJ51210.1 - 0.14 11.0 5.2 0.15 10.9 5.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Paramyxo_ncap PF00973.19 CDJ51210.1 - 0.14 11.0 6.7 0.16 10.9 6.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3408 PF11888.8 CDJ51210.1 - 0.19 11.9 10.5 0.26 11.4 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) 7tm_7 PF08395.12 CDJ51210.1 - 0.19 10.9 4.9 0.23 10.6 4.9 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Cellulose_synt PF03552.14 CDJ51210.1 - 0.2 10.1 1.7 0.23 9.9 1.7 1.2 1 0 0 1 1 1 0 Cellulose synthase RR_TM4-6 PF06459.12 CDJ51210.1 - 0.23 11.3 8.6 0.27 11.0 8.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MDM31_MDM32 PF08118.11 CDJ51210.1 - 0.27 9.9 5.4 0.31 9.7 5.4 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins PRC2_HTH_1 PF18118.1 CDJ51210.1 - 0.29 12.0 6.1 0.38 11.6 6.1 1.2 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain TFB6 PF17110.5 CDJ51210.1 - 0.34 10.6 6.8 0.45 10.3 6.8 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF3112 PF11309.8 CDJ51210.1 - 0.38 10.2 4.0 0.52 9.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) ZZ PF00569.17 CDJ51210.1 - 0.4 10.5 5.6 0.97 9.3 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type TERB2 PF15101.6 CDJ51210.1 - 0.58 10.2 17.8 0.77 9.8 17.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Baculo_PP31 PF05311.11 CDJ51210.1 - 0.58 9.6 9.5 0.7 9.3 9.5 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Cadherin_C_2 PF16492.5 CDJ51210.1 - 0.75 10.6 4.5 1.5 9.7 4.5 1.5 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Suf PF05843.14 CDJ51210.1 - 0.77 9.7 14.0 0.88 9.5 14.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4131 PF13567.6 CDJ51210.1 - 0.87 9.2 10.4 1.3 8.6 2.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) ORC_WH_C PF18137.1 CDJ51210.1 - 1.1 9.3 11.5 1.7 8.7 11.5 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal EPL1 PF10513.9 CDJ51210.1 - 1.3 9.4 12.3 1.8 9.0 12.3 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Med15 PF09606.10 CDJ51210.1 - 1.4 7.5 28.7 1.7 7.2 28.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ51210.1 - 1.4 8.4 39.7 2 8.0 39.7 1.1 1 0 0 1 1 1 0 Spt20 family BRF1 PF07741.13 CDJ51210.1 - 1.5 9.3 10.8 2.2 8.6 10.8 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Activator_LAG-3 PF11498.8 CDJ51210.1 - 1.8 7.5 39.3 2.3 7.1 39.3 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Consortin_C PF15281.6 CDJ51210.1 - 2.3 8.3 6.7 14 5.7 4.6 2.2 2 0 0 2 2 2 0 Consortin C-terminus Tim54 PF11711.8 CDJ51210.1 - 2.8 6.6 11.1 3.7 6.2 11.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 UPF0239 PF06783.11 CDJ51210.1 - 2.8 8.2 8.8 4.8 7.4 8.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) PIG-U PF06728.13 CDJ51210.1 - 2.9 6.8 7.3 4.3 6.3 7.3 1.4 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U MMR1 PF08505.10 CDJ51210.1 - 3.5 7.8 15.6 4.3 7.6 15.6 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Sec62 PF03839.16 CDJ51210.1 - 3.9 6.9 8.7 6.6 6.2 8.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_pol_Rbc25 PF08292.12 CDJ51210.1 - 4.4 7.5 10.9 7.2 6.9 10.9 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Dpy19 PF10034.9 CDJ51210.1 - 5.1 5.2 9.7 6.6 4.8 9.3 1.3 1 1 0 1 1 1 0 Q-cell neuroblast polarisation Folate_carrier PF01770.18 CDJ51210.1 - 5.9 5.5 13.7 10 4.7 13.7 1.4 1 1 0 1 1 1 0 Reduced folate carrier DcuA_DcuB PF03605.14 CDJ51210.1 - 6.2 5.6 13.1 9.8 5.0 12.4 1.6 1 1 1 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter DUF4770 PF15994.5 CDJ51210.1 - 8.1 6.6 17.7 11 6.2 17.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) RAB3GAP2_N PF14655.6 CDJ51210.1 - 8.3 5.6 20.7 0.021 14.1 6.0 2.0 1 1 1 2 2 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus O-antigen_lig PF13425.6 CDJ51210.1 - 9.1 4.9 10.2 20 3.8 10.2 1.5 1 1 0 1 1 1 0 O-antigen ligase like membrane protein Ctr PF04145.15 CDJ51210.1 - 9.6 6.8 11.5 17 6.0 11.5 1.4 1 1 0 1 1 1 0 Ctr copper transporter family PhoR PF11808.8 CDJ51212.1 - 0.14 12.5 4.9 0.75 10.2 0.7 2.2 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Trp_oprn_chp PF09534.10 CDJ51212.1 - 0.19 11.5 18.8 0.23 11.2 18.8 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4781 PF16013.5 CDJ51212.1 - 1.1 8.0 4.7 1.6 7.5 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Pex14_N PF04695.13 CDJ51213.1 - 0.019 15.7 27.5 0.12 13.0 0.5 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SPX PF03105.19 CDJ51213.1 - 0.068 13.1 17.9 0.049 13.5 7.3 2.1 2 0 0 2 2 2 0 SPX domain GRP PF07172.11 CDJ51213.1 - 0.084 13.6 2.4 7.4 7.3 0.1 3.2 3 0 0 3 3 3 0 Glycine rich protein family DUF4667 PF15700.5 CDJ51213.1 - 0.23 11.6 16.0 0.016 15.3 8.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Period_C PF12114.8 CDJ51213.1 - 0.29 10.7 16.1 0.25 10.9 11.0 2.4 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Lin-8 PF03353.15 CDJ51213.1 - 6 6.3 18.5 0.99 8.9 8.9 2.4 2 1 0 2 2 2 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ51214.1 - 9.3e-06 25.9 65.9 0.0032 17.5 31.5 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit HEM4 PF02602.15 CDJ51214.1 - 3.8e-05 23.2 11.2 0.0021 17.4 0.1 4.4 5 1 0 5 5 5 2 Uroporphyrinogen-III synthase HemD DDE_Tnp_IS1595 PF12762.7 CDJ51214.1 - 0.51 10.3 2.0 20 5.1 0.0 2.5 2 0 0 2 2 2 0 ISXO2-like transposase domain DUF2052 PF09747.9 CDJ51214.1 - 5.8 7.0 23.4 3 7.9 8.2 2.9 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Exonuc_VII_L PF02601.15 CDJ51214.1 - 6.9 6.1 28.5 0.25 10.9 11.8 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit TruD PF01142.18 CDJ51215.1 - 2.9e-16 59.3 1.4 3.5e-09 36.0 3.2 3.4 3 0 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) DUF1645 PF07816.11 CDJ51215.1 - 2.8e-05 24.8 13.9 2.8e-05 24.8 13.9 9.6 6 2 1 8 8 8 2 Protein of unknown function (DUF1645) TFIIA PF03153.13 CDJ51215.1 - 0.006 16.6 37.6 0.006 16.6 37.6 5.5 2 2 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit PTPRCAP PF15713.5 CDJ51215.1 - 0.13 12.5 0.0 0.13 12.5 0.0 7.9 8 2 1 9 9 9 0 Protein tyrosine phosphatase receptor type C-associated SARAF PF06682.12 CDJ51216.1 - 0.007 16.1 8.7 0.007 16.1 8.7 3.9 2 1 2 4 4 2 1 SOCE-associated regulatory factor of calcium homoeostasis Conotoxin PF02950.17 CDJ51216.1 - 0.055 14.5 2.2 0.055 14.5 2.2 5.9 4 2 1 5 5 4 0 Conotoxin DUF4064 PF13273.6 CDJ51216.1 - 0.073 13.3 0.3 0.073 13.3 0.3 5.0 3 1 2 5 5 4 0 Protein of unknown function (DUF4064) COPI_assoc PF08507.10 CDJ51216.1 - 0.18 11.9 0.2 0.18 11.9 0.2 2.4 2 0 0 2 2 2 0 COPI associated protein TLC PF03219.14 CDJ51216.1 - 0.23 10.2 2.6 0.47 9.1 2.6 1.5 1 0 0 1 1 1 0 TLC ATP/ADP transporter TAS2R PF05296.13 CDJ51216.1 - 0.5 9.4 4.8 0.89 8.6 4.8 1.4 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) Peptidase_S64 PF08192.11 CDJ51216.1 - 0.72 8.3 26.8 1.6 7.1 26.8 1.5 1 0 0 1 1 1 0 Peptidase family S64 DUF2207 PF09972.9 CDJ51216.1 - 0.93 8.2 2.4 1.2 7.9 0.1 2.3 1 1 1 3 3 3 0 Predicted membrane protein (DUF2207) RSN1_7TM PF02714.15 CDJ51216.1 - 1.4 8.1 5.9 4.6 6.5 0.6 2.2 2 0 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate Oxidored_q3 PF00499.20 CDJ51216.1 - 1.9 8.2 6.7 1.4 8.6 0.6 3.1 2 2 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 SKN1 PF03935.15 CDJ51216.1 - 3.5 5.9 11.0 0.18 10.2 2.2 2.4 2 1 1 3 3 3 0 Beta-glucan synthesis-associated protein (SKN1) DUF898 PF05987.13 CDJ51216.1 - 4.2 6.3 13.1 0.29 10.2 2.0 3.4 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Frizzled PF01534.17 CDJ51216.1 - 5.4 6.0 8.2 1.1 8.2 1.3 2.6 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region DDHD PF02862.17 CDJ51217.1 - 0.00051 20.3 5.1 0.00051 20.3 5.1 1.1 1 0 0 1 1 1 1 DDHD domain SpoIIP PF07454.11 CDJ51217.1 - 0.00089 18.8 9.6 0.00089 18.8 9.6 1.0 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Otopetrin PF03189.13 CDJ51217.1 - 0.0054 15.6 1.7 0.0045 15.9 1.7 1.0 1 0 0 1 1 1 1 Otopetrin EPL1 PF10513.9 CDJ51217.1 - 0.0059 17.0 11.4 0.0074 16.7 11.4 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like DUF5308 PF17233.2 CDJ51217.1 - 0.006 16.8 8.8 0.0068 16.6 8.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5308) Pex14_N PF04695.13 CDJ51217.1 - 0.0073 17.0 25.9 0.0094 16.6 25.9 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CTU2 PF10288.9 CDJ51217.1 - 0.045 14.0 9.9 0.063 13.5 9.9 1.3 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF3464 PF11947.8 CDJ51217.1 - 0.069 12.9 14.0 0.1 12.3 14.0 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RP-C_C PF11800.8 CDJ51217.1 - 0.14 12.3 12.3 0.16 12.1 12.3 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region RR_TM4-6 PF06459.12 CDJ51217.1 - 0.23 11.3 16.0 0.26 11.1 16.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PepSY_TM PF03929.16 CDJ51217.1 - 0.29 10.8 6.4 0.32 10.6 6.4 1.3 1 0 0 1 1 1 0 PepSY-associated TM region Asparaginase_2 PF01112.18 CDJ51217.1 - 0.44 9.5 5.8 0.54 9.2 5.8 1.1 1 0 0 1 1 1 0 Asparaginase FAM91_C PF14648.6 CDJ51217.1 - 0.45 9.3 5.6 0.5 9.2 5.6 1.1 1 0 0 1 1 1 0 FAM91 C-terminus SMN PF06003.12 CDJ51217.1 - 0.45 9.7 4.9 0.54 9.5 4.9 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) SLC12 PF03522.15 CDJ51217.1 - 0.47 9.4 16.3 0.54 9.2 16.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF2370 PF10176.9 CDJ51217.1 - 0.51 9.9 6.0 0.59 9.7 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) GPCR_chapero_1 PF11904.8 CDJ51217.1 - 0.54 9.6 8.8 0.61 9.5 8.8 1.1 1 0 0 1 1 1 0 GPCR-chaperone Plasmodium_Vir PF05795.11 CDJ51217.1 - 0.54 9.6 6.1 0.54 9.6 6.1 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NPR3 PF03666.13 CDJ51217.1 - 0.6 8.8 14.8 0.67 8.7 14.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Spem1 PF15670.5 CDJ51217.1 - 0.61 9.6 17.8 0.71 9.4 17.8 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Zip PF02535.22 CDJ51217.1 - 0.62 9.2 10.0 0.7 9.1 10.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 CDJ51217.1 - 0.64 8.2 13.1 0.73 8.1 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1943 PF09172.11 CDJ51217.1 - 0.67 9.1 7.4 0.79 8.9 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Presenilin PF01080.17 CDJ51217.1 - 0.79 8.4 22.5 1 8.0 22.5 1.1 1 0 0 1 1 1 0 Presenilin BORG_CEP PF14957.6 CDJ51217.1 - 1.1 10.4 11.4 1.3 10.2 11.4 1.1 1 0 0 1 1 1 0 Cdc42 effector Sec62 PF03839.16 CDJ51217.1 - 1.4 8.4 11.8 1.5 8.3 11.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 PPL5 PF18168.1 CDJ51217.1 - 1.4 8.1 12.0 1.8 7.8 12.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF4569 PF15133.6 CDJ51217.1 - 1.8 8.2 20.4 2.3 7.8 20.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Tim54 PF11711.8 CDJ51217.1 - 1.9 7.2 16.9 2.4 6.9 16.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 CDJ51217.1 - 1.9 8.5 16.1 2.4 8.2 16.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.6 CDJ51217.1 - 2.3 8.4 14.5 2.9 8.0 14.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 CDJ51217.1 - 2.4 8.1 48.0 3.2 7.6 48.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.11 CDJ51217.1 - 2.5 6.5 15.2 2.8 6.3 15.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 Lin-8 PF03353.15 CDJ51217.1 - 2.8 7.4 21.4 3.5 7.1 21.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.7 CDJ51217.1 - 3.2 5.8 16.6 3.4 5.7 16.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4175 PF13779.6 CDJ51217.1 - 3.4 5.5 46.3 4.2 5.2 46.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pet20 PF08692.10 CDJ51217.1 - 3.6 8.3 7.7 5 7.8 7.7 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Endostatin PF06482.11 CDJ51217.1 - 4.2 6.8 20.6 5.1 6.5 20.6 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PAT1 PF09770.9 CDJ51217.1 - 5.7 5.1 35.7 6.1 5.0 35.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ctr PF04145.15 CDJ51217.1 - 5.8 7.5 11.5 7.5 7.2 11.5 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF2126 PF09899.9 CDJ51217.1 - 6.1 4.8 14.2 7.3 4.5 14.2 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) UPF0560 PF10577.9 CDJ51217.1 - 7.1 5.0 33.0 8.8 4.7 33.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ndc1_Nup PF09531.10 CDJ51217.1 - 9.9 4.7 14.3 11 4.6 14.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ALMT PF11744.8 CDJ51217.1 - 10 4.9 15.9 12 4.6 15.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Aconitase_2_N PF06434.13 CDJ51218.1 - 0.024 14.3 1.9 0.024 14.3 1.9 1.0 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus DUF4820 PF16091.5 CDJ51218.1 - 0.077 12.4 10.9 0.082 12.3 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Connexin PF00029.19 CDJ51218.1 - 0.11 12.3 8.1 0.11 12.3 8.1 1.0 1 0 0 1 1 1 0 Connexin Spt20 PF12090.8 CDJ51218.1 - 0.12 12.0 34.0 0.13 11.9 34.0 1.0 1 0 0 1 1 1 0 Spt20 family DUF533 PF04391.12 CDJ51218.1 - 0.2 11.2 12.4 0.23 11.0 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Orf78 PF06024.12 CDJ51218.1 - 0.21 11.9 5.8 0.25 11.7 5.8 1.1 1 0 0 1 1 1 0 Orf78 (ac78) DnaJ-X PF14308.6 CDJ51218.1 - 0.41 10.1 8.6 0.46 9.9 8.6 1.0 1 0 0 1 1 1 0 X-domain of DnaJ-containing FAM176 PF14851.6 CDJ51218.1 - 0.41 10.3 7.3 0.42 10.3 7.3 1.0 1 0 0 1 1 1 0 FAM176 family DUF2722 PF10846.8 CDJ51218.1 - 0.43 9.5 28.8 0.47 9.3 28.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) GTA_holin_3TM PF11351.8 CDJ51218.1 - 0.51 10.9 12.4 0.57 10.7 12.4 1.1 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release G0-G1_switch_2 PF15103.6 CDJ51218.1 - 0.6 10.6 12.4 0.7 10.3 12.4 1.0 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF4578 PF15147.6 CDJ51218.1 - 0.62 10.9 17.3 0.76 10.7 17.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) EIIBC-GUT_N PF03612.14 CDJ51218.1 - 0.63 9.8 11.1 0.7 9.6 11.1 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CPSF100_C PF13299.6 CDJ51218.1 - 0.68 10.1 9.7 0.71 10.0 9.7 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 CDJ51218.1 - 0.72 9.3 10.8 0.72 9.3 10.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DivIC PF04977.15 CDJ51218.1 - 0.72 9.7 15.4 0.78 9.6 15.4 1.2 1 0 0 1 1 1 0 Septum formation initiator Pannexin_like PF12534.8 CDJ51218.1 - 0.74 8.8 10.1 0.8 8.7 10.1 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Pet20 PF08692.10 CDJ51218.1 - 0.76 10.5 5.5 0.82 10.4 5.5 1.0 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Coilin_N PF15862.5 CDJ51218.1 - 1 9.2 13.3 1 9.2 13.3 1.2 1 0 0 1 1 1 0 Coilin N-terminus EPL1 PF10513.9 CDJ51218.1 - 1 9.7 12.9 1.1 9.6 12.9 1.0 1 0 0 1 1 1 0 Enhancer of polycomb-like eIF-3_zeta PF05091.12 CDJ51218.1 - 1.2 8.0 16.9 1.3 8.0 16.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UPF0560 PF10577.9 CDJ51218.1 - 1.3 7.5 18.1 1.3 7.4 18.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3464 PF11947.8 CDJ51218.1 - 1.3 8.8 9.8 1.3 8.8 9.8 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF702 PF05142.12 CDJ51218.1 - 1.3 9.5 14.4 1.7 9.1 14.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) TERB2 PF15101.6 CDJ51218.1 - 1.4 8.9 18.2 1.5 8.8 18.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RAB3GAP2_N PF14655.6 CDJ51218.1 - 1.5 8.0 11.1 1.6 7.9 11.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.10 CDJ51218.1 - 1.7 7.2 30.0 1.6 7.3 30.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4834 PF16118.5 CDJ51218.1 - 1.7 9.6 15.9 2.2 9.3 15.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CobT PF06213.12 CDJ51218.1 - 1.9 7.8 16.8 2 7.7 16.8 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 CDJ51218.1 - 2 8.2 10.2 2.1 8.1 10.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AIF_C PF14721.6 CDJ51218.1 - 2 8.8 9.3 2.2 8.6 9.3 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Presenilin PF01080.17 CDJ51218.1 - 2 7.1 14.8 2.2 6.9 14.8 1.0 1 0 0 1 1 1 0 Presenilin FHIPEP PF00771.20 CDJ51218.1 - 2.1 6.7 8.1 2 6.8 8.1 1.0 1 0 0 1 1 1 0 FHIPEP family Ureide_permease PF07168.11 CDJ51218.1 - 2.2 7.0 4.9 2.3 6.9 4.9 1.0 1 0 0 1 1 1 0 Ureide permease V_ATPase_I PF01496.19 CDJ51218.1 - 2.2 6.1 12.5 2.3 6.0 12.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4770 PF15994.5 CDJ51218.1 - 2.2 8.5 12.7 2.3 8.4 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) RNA_pol_Rbc25 PF08292.12 CDJ51218.1 - 2.3 8.4 9.5 2.8 8.2 9.5 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 NACHT_N PF17100.5 CDJ51218.1 - 2.7 7.8 13.8 3.2 7.6 13.8 1.1 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase TFIIA PF03153.13 CDJ51218.1 - 3 7.8 32.2 3 7.7 32.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ51218.1 - 3.1 7.7 17.7 3.2 7.7 17.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MPM1 PF17234.2 CDJ51218.1 - 3.1 8.0 14.1 3.5 7.9 14.1 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Sec62 PF03839.16 CDJ51218.1 - 3.2 7.2 8.5 3.4 7.1 8.5 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Pex14_N PF04695.13 CDJ51218.1 - 3.4 8.3 20.8 3.8 8.1 20.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YABBY PF04690.13 CDJ51218.1 - 3.4 8.2 11.2 3.3 8.2 11.2 1.1 1 0 0 1 1 1 0 YABBY protein ALMT PF11744.8 CDJ51218.1 - 3.5 6.4 9.7 3.9 6.2 9.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Band_3_cyto PF07565.13 CDJ51218.1 - 4 7.2 13.5 4.4 7.0 13.5 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain O-antigen_lig PF13425.6 CDJ51218.1 - 4.1 6.1 3.7 4.4 6.0 3.7 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF1980 PF09323.10 CDJ51218.1 - 4.6 7.1 9.2 5 7.0 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DDHD PF02862.17 CDJ51218.1 - 4.7 7.3 12.6 4.9 7.2 12.6 1.0 1 0 0 1 1 1 0 DDHD domain Activator_LAG-3 PF11498.8 CDJ51218.1 - 4.8 6.0 37.0 5.2 5.9 37.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CLN3 PF02487.17 CDJ51218.1 - 5 6.1 9.5 5.3 6.0 9.5 1.0 1 0 0 1 1 1 0 CLN3 protein DUF853 PF05872.12 CDJ51218.1 - 5.2 5.5 11.2 5.6 5.4 11.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Folate_carrier PF01770.18 CDJ51218.1 - 5.2 5.7 7.9 5.5 5.6 7.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier FlaG PF03646.15 CDJ51218.1 - 5.6 7.2 17.4 6.4 7.0 17.4 1.2 1 0 0 1 1 1 0 FlaG protein Androgen_recep PF02166.16 CDJ51218.1 - 5.7 5.7 31.8 6.6 5.5 31.8 1.1 1 0 0 1 1 1 0 Androgen receptor EOS1 PF12326.8 CDJ51218.1 - 5.8 6.8 9.1 6 6.8 9.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein PepSY_TM PF03929.16 CDJ51218.1 - 6.6 6.3 8.9 7.1 6.2 8.9 1.0 1 0 0 1 1 1 0 PepSY-associated TM region FliP PF00813.20 CDJ51218.1 - 7.2 6.4 7.9 6.8 6.5 7.9 1.0 1 0 0 1 1 1 0 FliP family Roughex PF06020.11 CDJ51218.1 - 7.5 5.6 16.2 8.3 5.4 16.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Neur_chan_memb PF02932.16 CDJ51218.1 - 8.2 6.4 11.1 8.2 6.4 11.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 CDJ51218.1 - 8.8 5.6 14.2 9.5 5.5 14.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) F5_F8_type_C PF00754.25 CDJ51219.1 - 2e-14 53.8 0.1 1.6e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 F5/8 type C domain RNA_pol_3_Rpc31 PF11705.8 CDJ51219.1 - 2e-09 38.1 7.3 1.1e-08 35.6 7.3 2.1 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.10 CDJ51219.1 - 3.2 8.5 13.4 0.12 13.1 5.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) eIF3_N PF09440.10 CDJ51219.1 - 4.1 7.8 5.0 1.3 9.5 0.2 2.4 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain Uds1 PF15456.6 CDJ51219.1 - 7.6 6.7 8.2 0.2 11.8 0.2 2.5 3 0 0 3 3 3 0 Up-regulated During Septation Menin PF05053.13 CDJ51220.1 - 0.98 7.7 4.3 0.78 8.0 3.4 1.3 1 1 0 1 1 1 0 Menin RskA PF10099.9 CDJ51222.1 - 2.3e-05 24.7 7.5 2.3e-05 24.7 7.5 22.3 8 6 7 16 16 16 3 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ51222.1 - 0.0012 17.9 5.6 0.0012 17.9 5.6 20.0 16 5 2 20 20 20 7 Protein of unknown function (DUF2722) SARAF PF06682.12 CDJ51222.1 - 0.0034 17.1 4.6 0.0034 17.1 4.6 15.2 7 5 5 12 12 12 2 SOCE-associated regulatory factor of calcium homoeostasis Pho88 PF10032.9 CDJ51222.1 - 0.44 9.8 12.0 0.033 13.4 0.2 3.7 3 0 0 3 3 3 0 Phosphate transport (Pho88) Mucin PF01456.17 CDJ51222.1 - 1.9 8.4 0.0 1.9 8.4 0.0 16.2 14 4 1 15 15 15 0 Mucin-like glycoprotein DUF4401 PF14351.6 CDJ51223.1 - 0.031 13.6 4.2 0.45 9.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) TERB2 PF15101.6 CDJ51223.1 - 0.063 13.3 4.6 0.073 13.1 4.6 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SIS_2 PF13580.6 CDJ51223.1 - 0.24 11.4 7.7 0.066 13.2 3.9 1.8 2 0 0 2 2 2 0 SIS domain TFIIA PF03153.13 CDJ51223.1 - 0.31 11.0 18.2 0.33 10.9 18.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ51223.1 - 0.46 11.1 13.0 0.58 10.8 13.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4366 PF14283.6 CDJ51223.1 - 0.65 10.0 6.5 0.89 9.6 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RIFIN PF02009.16 CDJ51223.1 - 0.74 9.6 5.0 0.79 9.6 5.0 1.1 1 0 0 1 1 1 0 Rifin ABC2_membrane_2 PF12679.7 CDJ51223.1 - 0.84 8.9 6.0 1.1 8.5 6.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Suf PF05843.14 CDJ51223.1 - 1.6 8.6 8.3 1.7 8.5 8.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) 6PGD PF00393.19 CDJ51223.1 - 2.8 7.2 9.3 3.2 7.1 9.3 1.1 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain Spt20 PF12090.8 CDJ51223.1 - 4 7.0 20.2 4.5 6.8 20.2 1.1 1 0 0 1 1 1 0 Spt20 family Stevor PF17410.2 CDJ51223.1 - 4 6.9 4.6 4.6 6.7 4.6 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2722 PF10846.8 CDJ51223.1 - 6.3 5.6 14.3 7.2 5.4 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4342 PF14242.6 CDJ51223.1 - 9.1 6.4 14.5 4.6 7.3 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) HCO3_cotransp PF00955.21 CDJ51224.1 - 0.69 8.7 2.5 0.91 8.3 2.5 1.3 1 0 0 1 1 1 0 HCO3- transporter family DcuA_DcuB PF03605.14 CDJ51224.1 - 1.3 7.9 7.4 2.3 7.0 7.4 1.4 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF4746 PF15928.5 CDJ51224.1 - 1.5 8.2 9.2 3 7.2 9.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) Omp_AT PF11557.8 CDJ51224.1 - 2 7.3 5.6 3 6.7 5.6 1.2 1 0 0 1 1 1 0 Solitary outer membrane autotransporter beta-barrel domain SpoIIP PF07454.11 CDJ51224.1 - 3 7.2 16.1 0.041 13.3 5.6 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Adeno_PV PF03910.13 CDJ51224.1 - 5.6 5.6 9.7 7.9 5.1 9.7 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV EPL1 PF10513.9 CDJ51224.1 - 6.8 7.1 23.3 0.093 13.1 10.6 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like CLN3 PF02487.17 CDJ51224.1 - 6.8 5.6 13.5 0.12 11.4 6.1 1.7 2 0 0 2 2 2 0 CLN3 protein SpoVR PF04293.13 CDJ51224.1 - 7.5 5.1 16.4 0.021 13.5 6.5 1.6 2 0 0 2 2 2 0 SpoVR like protein CTNNB1_binding PF08347.11 CDJ51224.1 - 8.5 6.5 14.5 0.061 13.5 5.1 1.9 2 0 0 2 2 2 0 N-terminal CTNNB1 binding BatA PF07584.11 CDJ51225.1 - 0.036 14.4 2.6 0.036 14.4 2.6 4.3 4 1 1 5 5 5 0 Aerotolerance regulator N-terminal SR-25 PF10500.9 CDJ51226.1 - 7.1e-06 25.8 17.5 7.1e-06 25.8 17.5 7.7 7 1 0 7 7 7 3 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ51226.1 - 0.34 11.0 0.0 0.34 11.0 0.0 8.2 6 3 0 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 Ferlin_C PF16165.5 CDJ51226.1 - 3.5 7.5 5.9 38 4.2 7.2 2.0 2 0 0 2 2 2 0 Ferlin C-terminus CSG2 PF16965.5 CDJ51227.1 - 0.09 11.7 12.0 0.097 11.6 12.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator CLN3 PF02487.17 CDJ51227.1 - 0.12 11.3 18.7 0.13 11.3 18.7 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4746 PF15928.5 CDJ51227.1 - 0.13 11.6 17.8 0.15 11.5 17.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SLC12 PF03522.15 CDJ51227.1 - 0.15 11.1 28.2 0.15 11.0 28.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Velvet PF11754.8 CDJ51227.1 - 0.21 11.5 21.6 0.21 11.5 21.6 1.1 1 0 0 1 1 1 0 Velvet factor GAGA_bind PF06217.12 CDJ51227.1 - 0.41 10.9 23.7 0.41 10.9 23.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF913 PF06025.12 CDJ51227.1 - 0.47 9.4 16.0 0.52 9.2 16.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 CDJ51227.1 - 0.74 8.5 28.5 0.79 8.4 28.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tmp39 PF10271.9 CDJ51227.1 - 1.2 8.1 7.1 1.3 8.0 7.1 1.0 1 0 0 1 1 1 0 Putative transmembrane protein MDM10 PF12519.8 CDJ51227.1 - 1.2 7.9 23.9 1.2 7.9 23.9 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PTPRCAP PF15713.5 CDJ51227.1 - 1.3 9.3 27.4 1.8 8.8 27.4 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4228 PF14009.6 CDJ51227.1 - 1.3 9.3 17.4 1.5 9.2 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) AUX_IAA PF02309.16 CDJ51227.1 - 1.6 8.5 18.7 1.6 8.5 18.7 1.1 1 0 0 1 1 1 0 AUX/IAA family UPF0565 PF10561.9 CDJ51227.1 - 1.9 7.6 17.7 2.3 7.4 17.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 XRN_M PF17846.1 CDJ51227.1 - 2 7.3 21.9 2.2 7.1 21.9 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Presenilin PF01080.17 CDJ51227.1 - 2.1 7.0 37.5 2.4 6.8 37.5 1.0 1 0 0 1 1 1 0 Presenilin CRT10 PF08728.10 CDJ51227.1 - 2.6 6.1 21.9 2.8 6.0 21.9 1.0 1 0 0 1 1 1 0 CRT10 MAJIN PF15077.6 CDJ51227.1 - 2.7 7.7 18.7 2.7 7.7 18.7 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein SID-1_RNA_chan PF13965.6 CDJ51227.1 - 2.8 6.2 13.9 3 6.1 13.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Med19 PF10278.9 CDJ51227.1 - 3.6 7.5 26.7 4 7.3 26.7 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CobT PF06213.12 CDJ51227.1 - 3.6 6.9 41.4 4.7 6.5 41.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 CDJ51227.1 - 4 7.2 34.7 4.4 7.0 34.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 CDJ51227.1 - 4.5 7.4 36.0 4.9 7.2 36.0 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RNA_pol_Rpc4 PF05132.14 CDJ51227.1 - 7.5 7.0 27.1 11 6.5 27.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 TFIIA PF03153.13 CDJ51228.1 - 0.36 10.8 20.8 0.47 10.4 20.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rpp20 PF12328.8 CDJ51228.1 - 3.4 7.6 7.6 5.1 7.0 7.6 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF2722 PF10846.8 CDJ51229.1 - 6.6e-06 25.3 7.0 6.6e-06 25.3 7.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Sporozoite_P67 PF05642.11 CDJ51229.1 - 0.0025 16.0 0.0 0.0025 16.0 0.0 4.2 3 2 0 4 4 4 2 Sporozoite P67 surface antigen DUF3464 PF11947.8 CDJ51229.1 - 0.0036 17.1 2.0 0.0036 17.1 2.0 4.4 5 0 0 5 5 5 1 Photosynthesis affected mutant 68 rRNA_processing PF08524.11 CDJ51229.1 - 0.016 15.2 27.0 0.027 14.5 7.8 3.5 3 0 0 3 3 3 0 rRNA processing SAPS PF04499.15 CDJ51229.1 - 0.037 12.8 9.5 0.044 12.6 4.1 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Peptidase_S64 PF08192.11 CDJ51229.1 - 2.9 6.3 24.9 0.011 14.3 13.1 2.0 2 0 0 2 2 2 0 Peptidase family S64 FA_desaturase PF00487.24 CDJ51229.1 - 9.4 6.0 0.0 9.4 6.0 0.0 3.8 3 1 0 4 4 4 0 Fatty acid desaturase DEAD PF00270.29 CDJ51230.1 - 9.9e-07 28.7 0.0 9.6e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase YbgS PF13985.6 CDJ51232.1 - 0.0027 18.0 6.2 0.004 17.4 6.2 1.4 1 0 0 1 1 1 1 YbgS-like protein FHIPEP PF00771.20 CDJ51232.1 - 0.0094 14.5 6.8 0.011 14.2 6.8 1.0 1 0 0 1 1 1 1 FHIPEP family Pex26 PF07163.12 CDJ51232.1 - 0.012 15.0 11.1 0.013 14.8 11.1 1.2 1 0 0 1 1 1 0 Pex26 protein SpoIIP PF07454.11 CDJ51232.1 - 0.013 15.0 10.7 0.013 15.0 10.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 CDJ51232.1 - 0.016 15.2 41.6 0.019 15.0 41.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AIF_C PF14721.6 CDJ51232.1 - 0.024 15.0 9.6 0.024 15.0 9.6 1.6 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Suf PF05843.14 CDJ51232.1 - 0.028 14.4 19.7 0.037 14.0 19.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ51232.1 - 0.029 13.1 16.9 0.03 13.1 16.9 1.1 1 0 0 1 1 1 0 Presenilin FAM91_C PF14648.6 CDJ51232.1 - 0.047 12.5 2.3 0.044 12.6 2.3 1.1 1 0 0 1 1 1 0 FAM91 C-terminus DUF2370 PF10176.9 CDJ51232.1 - 0.064 12.9 3.4 0.069 12.8 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF1980 PF09323.10 CDJ51232.1 - 0.071 13.0 7.9 0.086 12.7 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Helicase_RecD PF05127.14 CDJ51232.1 - 0.072 12.9 11.7 0.096 12.5 11.7 1.1 1 0 0 1 1 1 0 Helicase EOS1 PF12326.8 CDJ51232.1 - 0.09 12.7 5.6 0.11 12.5 5.6 1.3 1 0 0 1 1 1 0 N-glycosylation protein SDH_beta PF03315.15 CDJ51232.1 - 0.092 13.1 4.3 0.09 13.1 4.3 1.1 1 0 0 1 1 1 0 Serine dehydratase beta chain Asparaginase_2 PF01112.18 CDJ51232.1 - 0.099 11.6 8.5 0.11 11.5 8.5 1.2 1 0 0 1 1 1 0 Asparaginase DUF2126 PF09899.9 CDJ51232.1 - 0.1 10.7 9.7 0.11 10.6 9.7 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DDHD PF02862.17 CDJ51232.1 - 0.1 12.7 13.4 0.12 12.5 13.4 1.1 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 CDJ51232.1 - 0.1 11.5 8.4 0.12 11.4 8.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2232 PF09991.9 CDJ51232.1 - 0.11 11.7 2.4 0.13 11.4 2.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) G6B PF15096.6 CDJ51232.1 - 0.11 12.2 2.4 0.14 12.0 2.4 1.2 1 0 0 1 1 1 0 G6B family TRAP_alpha PF03896.16 CDJ51232.1 - 0.11 11.6 5.0 0.15 11.3 5.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CSG2 PF16965.5 CDJ51232.1 - 0.12 11.3 5.5 0.12 11.3 5.5 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Zip PF02535.22 CDJ51232.1 - 0.13 11.5 5.6 0.13 11.4 5.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 CDJ51232.1 - 0.13 10.6 3.6 0.14 10.5 3.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LAP1C PF05609.12 CDJ51232.1 - 0.17 10.9 18.4 0.18 10.8 18.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_U57 PF05582.12 CDJ51232.1 - 0.17 11.1 6.3 0.19 11.0 6.3 1.1 1 0 0 1 1 1 0 YabG peptidase U57 CDC45 PF02724.14 CDJ51232.1 - 0.19 10.0 9.2 0.18 10.0 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Otopetrin PF03189.13 CDJ51232.1 - 0.26 10.1 5.0 0.26 10.0 5.0 1.1 1 0 0 1 1 1 0 Otopetrin Folate_carrier PF01770.18 CDJ51232.1 - 0.26 10.0 4.2 0.29 9.8 4.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier CLN3 PF02487.17 CDJ51232.1 - 0.28 10.2 8.1 0.29 10.1 8.1 1.1 1 0 0 1 1 1 0 CLN3 protein Pex14_N PF04695.13 CDJ51232.1 - 0.28 11.8 31.4 0.41 11.3 31.4 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM60A PF15396.6 CDJ51232.1 - 0.28 11.2 13.0 0.34 10.9 13.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PIP5K PF01504.18 CDJ51232.1 - 0.3 10.3 9.0 0.31 10.2 9.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SOBP PF15279.6 CDJ51232.1 - 0.35 11.4 13.8 0.37 11.3 13.8 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Serinc PF03348.15 CDJ51232.1 - 0.35 9.7 9.1 0.39 9.6 9.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) OATP PF03137.20 CDJ51232.1 - 0.37 9.0 4.0 0.38 9.0 4.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family O-antigen_lig PF13425.6 CDJ51232.1 - 0.38 9.5 3.3 0.43 9.3 3.3 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PigN PF04987.14 CDJ51232.1 - 0.39 9.5 5.2 0.46 9.3 5.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF4338 PF14236.6 CDJ51232.1 - 0.45 9.7 7.7 0.65 9.2 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) Hamartin PF04388.12 CDJ51232.1 - 0.48 9.0 13.7 0.49 9.0 13.7 1.0 1 0 0 1 1 1 0 Hamartin protein Plasmodium_Vir PF05795.11 CDJ51232.1 - 0.5 9.7 7.1 0.51 9.7 7.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SMYLE_N PF18615.1 CDJ51232.1 - 0.53 9.8 12.1 0.62 9.6 12.1 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain RR_TM4-6 PF06459.12 CDJ51232.1 - 0.57 10.0 18.8 0.65 9.8 18.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDDD PF10161.9 CDJ51232.1 - 0.63 9.8 2.6 2.6 7.9 2.6 2.1 1 1 0 1 1 1 0 Putative mitochondrial precursor protein LMBR1 PF04791.16 CDJ51232.1 - 0.68 8.8 7.3 0.7 8.7 7.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Tim54 PF11711.8 CDJ51232.1 - 0.8 8.4 13.8 0.89 8.3 13.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Band_3_cyto PF07565.13 CDJ51232.1 - 0.87 9.3 14.2 0.92 9.3 14.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4518 PF15008.6 CDJ51232.1 - 0.91 8.6 13.0 1.1 8.3 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Membralin PF09746.9 CDJ51232.1 - 1.1 8.2 6.5 1.2 8.1 6.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein BAF1_ABF1 PF04684.13 CDJ51232.1 - 1.2 8.1 19.3 1.4 7.9 19.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF5521 PF17659.1 CDJ51232.1 - 1.3 6.8 8.1 1.4 6.7 8.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) MDM10 PF12519.8 CDJ51232.1 - 1.3 7.8 10.8 1.3 7.8 10.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Neur_chan_memb PF02932.16 CDJ51232.1 - 1.3 9.0 12.8 1.5 8.8 12.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 CDJ51232.1 - 1.4 6.7 14.4 1.4 6.7 14.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EIF4E-T PF10477.9 CDJ51232.1 - 1.5 7.6 19.8 1.6 7.5 19.8 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Peptidase_S15 PF02129.18 CDJ51232.1 - 1.6 8.3 13.4 2 8.0 13.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S64 PF08192.11 CDJ51232.1 - 1.7 7.0 11.3 1.7 7.0 11.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Med15 PF09606.10 CDJ51232.1 - 1.9 7.1 36.6 2.3 6.8 36.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF5427 PF10310.9 CDJ51232.1 - 1.9 7.4 21.1 2.3 7.1 21.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 CDJ51232.1 - 1.9 7.4 15.5 2.2 7.2 15.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hydin_ADK PF17213.3 CDJ51232.1 - 2 8.7 17.9 2.4 8.4 17.9 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain HCO3_cotransp PF00955.21 CDJ51232.1 - 2 7.1 4.2 2.2 7.0 4.2 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF4820 PF16091.5 CDJ51232.1 - 2.1 7.7 18.8 2.5 7.4 18.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CD20 PF04103.15 CDJ51232.1 - 2.1 8.4 3.9 5 7.2 3.9 1.7 1 1 0 1 1 1 0 CD20-like family Exonuc_VII_L PF02601.15 CDJ51232.1 - 2.5 7.6 19.6 3 7.3 19.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.6 CDJ51232.1 - 2.7 8.5 15.3 3 8.3 15.3 1.2 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.9 CDJ51232.1 - 2.8 6.1 30.2 3 6.0 30.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HemX PF04375.14 CDJ51232.1 - 2.9 7.1 31.5 3.4 6.9 31.5 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2828 PF11443.8 CDJ51232.1 - 3 5.8 14.9 3.1 5.8 14.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) UPF0560 PF10577.9 CDJ51232.1 - 3 6.2 21.8 3.2 6.1 21.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Velvet PF11754.8 CDJ51232.1 - 3.1 7.7 18.8 3.5 7.5 18.8 1.1 1 0 0 1 1 1 0 Velvet factor Spem1 PF15670.5 CDJ51232.1 - 3.6 7.1 14.3 4.1 6.9 14.3 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 R_equi_Vir PF05526.11 CDJ51232.1 - 3.6 7.4 14.0 5 6.9 14.0 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Pannexin_like PF12534.8 CDJ51232.1 - 3.8 6.5 11.7 4.9 6.1 11.7 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF3450 PF11932.8 CDJ51232.1 - 4 6.7 30.5 5 6.4 30.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Trp_oprn_chp PF09534.10 CDJ51232.1 - 4.5 7.0 19.4 14 5.4 19.4 1.8 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Endostatin PF06482.11 CDJ51232.1 - 4.5 6.6 16.4 5 6.5 16.4 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin ALMT PF11744.8 CDJ51232.1 - 4.6 6.0 12.8 5.3 5.7 12.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4179 PF13786.6 CDJ51232.1 - 5 7.7 8.8 9.9 6.7 8.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Asp-B-Hydro_N PF05279.11 CDJ51232.1 - 5.1 7.1 12.6 6 6.9 12.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TALPID3 PF15324.6 CDJ51232.1 - 5.1 4.6 25.8 5.2 4.6 25.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target REC114-like PF15165.6 CDJ51232.1 - 5.8 6.6 19.1 6.5 6.5 19.1 1.1 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Pal1 PF08316.11 CDJ51232.1 - 6.9 7.4 10.6 9.1 7.0 10.6 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein eIF-3_zeta PF05091.12 CDJ51232.1 - 7.1 5.5 24.3 7.8 5.3 24.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EMC3_TMCO1 PF01956.16 CDJ51232.1 - 7.4 6.3 11.9 9.8 5.9 11.9 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4569 PF15133.6 CDJ51232.1 - 7.9 6.1 18.5 9.5 5.8 18.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF778 PF05608.12 CDJ51232.1 - 9.1 6.6 15.2 11 6.3 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) WTX PF09422.10 CDJ51232.1 - 9.3 5.2 15.0 11 5.0 15.0 1.0 1 0 0 1 1 1 0 WTX protein Roughex PF06020.11 CDJ51232.1 - 9.5 5.2 17.7 13 4.8 17.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein zf-C2H2_2 PF12756.7 CDJ51233.1 - 0.034 14.5 0.1 0.093 13.1 0.0 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Tnp_zf-ribbon_2 PF13842.6 CDJ51233.1 - 0.056 14.3 6.9 1 10.2 0.1 3.2 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon RNA_POL_M_15KD PF02150.16 CDJ51233.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.7 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit DNA_RNApol_7kD PF03604.13 CDJ51233.1 - 2.2 8.0 9.4 8.9 6.1 0.3 3.8 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Hist_deacetyl PF00850.19 CDJ51234.1 - 5.1e-74 249.5 0.0 2.2e-73 247.4 0.0 1.8 1 1 0 1 1 1 1 Histone deacetylase domain DnaJ PF00226.31 CDJ51235.1 - 3.6e-25 87.8 1.0 7.3e-25 86.9 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain Ribosomal_60s PF00428.19 CDJ51236.1 - 0.091 13.4 11.7 0.2 12.3 11.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein CCDC53 PF10152.9 CDJ51237.1 - 0.017 15.6 0.9 0.017 15.6 0.9 4.2 2 1 1 3 3 3 0 Subunit CCDC53 of WASH complex GREB1 PF15782.5 CDJ51237.1 - 2.8 5.0 22.5 3.6 4.6 22.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 CDJ51237.1 - 3.4 6.2 25.9 4.4 5.9 25.9 1.3 1 0 0 1 1 1 0 Hamartin protein Exonuc_VII_L PF02601.15 CDJ51237.1 - 6.8 6.2 29.7 3.8e+02 0.4 29.6 2.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_S64 PF08192.11 CDJ51237.1 - 7.4 4.9 20.1 11 4.3 20.1 1.2 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.13 CDJ51238.1 - 2.5 8.0 36.2 0.05 13.6 11.0 2.7 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-CCCH PF00642.24 CDJ51239.1 - 0.00035 20.4 18.5 0.054 13.4 1.3 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ51239.1 - 0.0014 18.6 1.3 0.0014 18.6 1.3 3.2 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ51239.1 - 0.0046 16.7 0.9 0.0046 16.7 0.9 3.3 3 0 0 3 3 3 3 CCCH-type zinc finger PFK PF00365.20 CDJ51240.1 - 1.2e-40 139.6 4.4 9.2e-34 117.1 0.0 4.2 2 2 0 2 2 2 2 Phosphofructokinase PTS_EIIC_2 PF13303.6 CDJ51240.1 - 0.023 13.7 5.0 0.062 12.3 5.0 1.7 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF755 PF05501.11 CDJ51240.1 - 7.2 6.9 7.8 0.6 10.4 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SUIM_assoc PF16619.5 CDJ51241.1 - 1.6e-05 24.9 0.0 1.6e-05 24.9 0.0 4.7 2 2 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 MID_MedPIWI PF18296.1 CDJ51241.1 - 0.0018 18.1 2.9 0.0018 18.1 2.9 2.1 2 0 0 2 2 2 1 MID domain of medPIWI ALMT PF11744.8 CDJ51241.1 - 0.0041 16.0 5.4 0.0041 16.0 5.4 2.1 2 0 0 2 2 2 1 Aluminium activated malate transporter Coilin_N PF15862.5 CDJ51241.1 - 0.0072 16.1 1.4 0.0072 16.1 1.4 2.3 2 0 0 2 2 2 1 Coilin N-terminus Pex14_N PF04695.13 CDJ51241.1 - 0.0072 17.0 33.2 0.091 13.4 11.9 2.2 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.9 CDJ51241.1 - 0.016 14.8 10.4 0.016 14.8 10.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ51241.1 - 0.036 14.6 18.4 0.61 10.6 6.7 2.2 2 0 0 2 2 2 0 TCP family transcription factor TFIIA PF03153.13 CDJ51241.1 - 0.25 11.3 58.6 0.045 13.7 27.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ51241.1 - 0.6 10.0 24.4 1.4 8.8 9.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) EPL1 PF10513.9 CDJ51241.1 - 1.5 9.2 21.8 1.3 9.4 5.1 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like FAM60A PF15396.6 CDJ51241.1 - 1.7 8.6 12.7 1.3 8.9 1.2 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Zip PF02535.22 CDJ51241.1 - 1.8 7.7 10.0 0.33 10.1 0.5 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Bestrophin PF01062.21 CDJ51241.1 - 2.2 7.6 6.7 4 6.7 6.7 1.5 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Med15 PF09606.10 CDJ51241.1 - 3.7 6.1 52.4 0.17 10.5 25.7 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.17 CDJ51241.1 - 5.5 7.1 22.9 1.8 8.7 5.2 2.4 2 1 0 2 2 2 0 DDHD domain MMR1 PF08505.10 CDJ51241.1 - 5.7 7.2 26.9 6.3 7.0 9.3 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein CCSAP PF15748.5 CDJ51241.1 - 6.3 6.9 27.3 5.9 7.0 6.7 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF4228 PF14009.6 CDJ51241.1 - 6.9 7.0 14.6 5.4 7.4 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Rpp20 PF12328.8 CDJ51241.1 - 8.6 6.3 16.3 0.93 9.5 4.6 2.5 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Adaptin_binding PF10199.9 CDJ51242.1 - 0.0037 17.9 0.7 0.0037 17.9 0.7 2.1 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Anemone_cytotox PF06369.12 CDJ51242.1 - 0.13 11.8 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Sea anemone cytotoxic protein SDA1 PF05285.12 CDJ51242.1 - 4.3 6.7 11.0 0.3 10.5 3.0 2.3 1 1 1 2 2 2 0 SDA1 ANAPC_CDC26 PF10471.9 CDJ51242.1 - 7.3 7.5 32.4 2.6 8.9 6.8 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 SR-25 PF10500.9 CDJ51243.1 - 0.0005 19.8 1.4 0.0005 19.8 1.4 3.6 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ51243.1 - 0.0024 18.2 15.9 0.0024 18.2 15.9 5.9 3 2 2 5 5 5 1 Anti-sigma-K factor rskA DUF4667 PF15700.5 CDJ51243.1 - 0.062 13.4 23.3 0.73 9.9 11.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Lin-8 PF03353.15 CDJ51243.1 - 7.9 5.9 25.4 1.3 8.5 9.5 2.5 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist Pox_MCEL PF03291.16 CDJ51244.1 - 8.5e-10 38.2 0.1 1.6e-08 34.1 0.0 2.5 2 1 1 3 3 3 1 mRNA capping enzyme Methyltransf_12 PF08242.12 CDJ51244.1 - 0.00022 21.9 0.4 0.0013 19.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain SR-25 PF10500.9 CDJ51244.1 - 0.00024 20.8 5.0 0.00037 20.2 5.0 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Methyltransf_11 PF08241.12 CDJ51244.1 - 0.0003 21.4 0.0 0.00089 19.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ51244.1 - 0.00039 20.2 0.5 0.00039 20.2 0.5 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ51244.1 - 0.0011 19.6 0.8 0.0025 18.5 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain IMUP PF15761.5 CDJ51244.1 - 0.19 12.4 5.6 0.38 11.5 5.6 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Cnd1_N PF12922.7 CDJ51244.1 - 1.6 8.5 9.2 1.1 9.1 6.2 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term DUF3446 PF11928.8 CDJ51244.1 - 4.1 7.8 13.3 9.1 6.7 12.8 1.7 1 1 0 1 1 1 0 Early growth response N-terminal domain PIP5K PF01504.18 CDJ51245.1 - 0.062 12.5 0.0 0.062 12.5 0.0 2.2 1 1 1 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Neur_chan_memb PF02932.16 CDJ51245.1 - 1.4 8.9 25.8 0.13 12.3 17.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CDJ51245.1 - 3 7.0 10.6 5.7 6.0 10.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.16 CDJ51245.1 - 5 6.3 12.6 10 5.2 12.6 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BRCA2 PF00634.18 CDJ51246.1 - 5.4e-30 102.8 11.5 0.00014 21.4 0.1 7.4 7 0 0 7 7 7 7 BRCA2 repeat BRCA-2_OB1 PF09103.10 CDJ51246.1 - 0.00032 20.6 4.3 0.00083 19.3 0.0 4.3 3 0 0 3 3 3 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 TCP PF03634.13 CDJ51246.1 - 0.0045 17.6 1.0 0.0045 17.6 1.0 15.2 10 4 4 14 14 14 1 TCP family transcription factor SARAF PF06682.12 CDJ51247.1 - 0.0002 21.1 5.9 0.0002 21.1 5.9 4.9 5 1 0 5 5 5 2 SOCE-associated regulatory factor of calcium homoeostasis DUF3747 PF12565.8 CDJ51249.1 - 1.5 8.1 8.5 0.16 11.4 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3747) RskA PF10099.9 CDJ51250.1 - 0.012 15.9 0.0 0.012 15.9 0.0 7.8 3 1 3 7 7 7 0 Anti-sigma-K factor rskA Glycos_transf_1 PF00534.20 CDJ51250.1 - 0.14 11.6 2.7 0.17 11.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 Peroxin-13_N PF04088.13 CDJ51250.1 - 0.6 10.4 26.9 2.5 8.4 0.3 6.4 6 0 0 6 6 6 0 Peroxin 13, N-terminal region Dak1 PF02733.17 CDJ51250.1 - 0.63 8.9 6.3 0.61 8.9 3.4 2.5 4 0 0 4 4 4 0 Dak1 domain Peptidase_C48 PF02902.19 CDJ51251.1 - 8.6e-12 45.4 0.0 1.6e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Activator_LAG-3 PF11498.8 CDJ51251.1 - 0.51 9.2 45.4 1.3 7.9 45.4 1.7 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SR-25 PF10500.9 CDJ51251.1 - 2.5 7.6 14.9 10 5.7 14.9 2.1 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPPK_C PF12555.8 CDJ51252.1 - 0.041 13.9 1.3 0.041 13.9 1.3 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal LRR19-TM PF15176.6 CDJ51252.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Mannosyl_trans4 PF15971.5 CDJ51254.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase TFIIA PF03153.13 CDJ51256.1 - 0.0061 16.6 31.9 0.0084 16.1 31.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Caldesmon PF02029.15 CDJ51256.1 - 0.46 9.2 42.1 0.68 8.6 42.1 1.2 1 0 0 1 1 1 0 Caldesmon CDC27 PF09507.10 CDJ51256.1 - 1.1 8.6 31.5 2.5 7.4 31.5 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Neur_chan_memb PF02932.16 CDJ51256.1 - 1.4 8.9 11.2 3.4 7.7 11.2 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 CDJ51256.1 - 2.2 6.3 24.0 3.8 5.5 24.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CDJ51256.1 - 5.2 5.7 30.6 8.2 5.1 30.6 1.2 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 CDJ51256.1 - 5.5 6.0 17.7 9.9 5.1 17.7 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Asp-B-Hydro_N PF05279.11 CDJ51256.1 - 5.6 6.9 26.4 9.1 6.3 26.4 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4407 PF14362.6 CDJ51256.1 - 8.7 5.6 12.7 14 4.9 12.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2722 PF10846.8 CDJ51257.1 - 0.00073 18.6 16.4 0.00073 18.6 16.4 3.2 2 1 1 3 3 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ51257.1 - 0.0036 17.4 19.4 0.0036 17.4 19.4 3.8 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit DUF5308 PF17233.2 CDJ51257.1 - 0.01 16.1 0.0 0.01 16.1 0.0 4.4 3 1 1 4 4 2 0 Family of unknown function (DUF5308) DUF4834 PF16118.5 CDJ51257.1 - 0.015 16.2 4.5 0.015 16.2 4.5 3.7 3 1 0 3 3 2 0 Domain of unknown function (DUF4834) CSG2 PF16965.5 CDJ51257.1 - 0.018 14.0 7.1 0.28 10.1 1.9 2.4 2 0 0 2 2 2 0 Ceramide synthase regulator Otopetrin PF03189.13 CDJ51257.1 - 0.019 13.8 2.8 0.11 11.2 2.9 2.1 1 1 0 1 1 1 0 Otopetrin SID-1_RNA_chan PF13965.6 CDJ51257.1 - 0.02 13.3 4.9 2.2 6.6 0.0 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 EMC3_TMCO1 PF01956.16 CDJ51257.1 - 0.037 13.8 0.1 0.037 13.8 0.1 3.3 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like Pentapeptide_4 PF13599.6 CDJ51257.1 - 0.068 13.4 0.1 0.22 11.7 0.1 1.8 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Kei1 PF08552.11 CDJ51257.1 - 0.6 10.0 0.0 0.6 10.0 0.0 5.1 4 1 0 4 4 3 0 Inositolphosphorylceramide synthase subunit Kei1 EOS1 PF12326.8 CDJ51257.1 - 1.3 8.9 0.0 1.3 8.9 0.0 2.8 2 1 0 2 2 1 0 N-glycosylation protein MMR1 PF08505.10 CDJ51257.1 - 2.5 8.3 44.1 0.59 10.4 8.3 3.2 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein DUF1980 PF09323.10 CDJ51257.1 - 3.7 7.4 27.3 0.067 13.1 0.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Band_3_cyto PF07565.13 CDJ51257.1 - 4.5 7.0 31.1 0.74 9.6 3.7 3.2 3 0 0 3 3 3 0 Band 3 cytoplasmic domain CobT PF06213.12 CDJ51259.1 - 3.6 6.9 21.5 3.6 6.9 21.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1180 PF06679.12 CDJ51259.1 - 6.6 7.1 6.8 7.4 7.0 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) FAM176 PF14851.6 CDJ51259.1 - 8.4 6.0 9.3 12 5.6 9.3 1.3 1 0 0 1 1 1 0 FAM176 family Sin_N PF04801.13 CDJ51260.1 - 0.0016 17.7 22.8 0.0033 16.7 22.7 1.4 1 1 0 1 1 1 1 Sin-like protein conserved region SLC12 PF03522.15 CDJ51260.1 - 5.5 5.9 21.4 1.5 7.8 6.4 2.0 2 0 0 2 2 2 0 Solute carrier family 12 RskA PF10099.9 CDJ51261.1 - 0.0028 18.0 14.7 0.0028 18.0 14.7 39.6 6 5 12 18 18 18 5 Anti-sigma-K factor rskA PhoLip_ATPase_N PF16209.5 CDJ51262.1 - 7.6e-24 83.2 0.9 1.9e-23 81.9 0.9 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal TFIIA PF03153.13 CDJ51262.1 - 6.9e-05 23.0 28.8 7.6e-05 22.9 28.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ51262.1 - 0.0024 17.0 14.2 0.0027 16.9 14.2 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor SART-1 PF03343.13 CDJ51262.1 - 0.011 14.3 23.3 0.014 14.0 23.3 1.1 1 0 0 1 1 1 0 SART-1 family Ribosomal_60s PF00428.19 CDJ51262.1 - 0.012 16.1 16.3 0.015 15.9 10.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein SAPS PF04499.15 CDJ51262.1 - 0.045 12.5 7.4 0.058 12.2 7.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MDM10 PF12519.8 CDJ51262.1 - 0.046 12.6 6.8 0.066 12.1 6.8 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4179 PF13786.6 CDJ51262.1 - 0.33 11.4 5.0 6 7.4 3.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) DUF572 PF04502.13 CDJ51262.1 - 0.39 10.3 15.4 0.55 9.8 15.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PPP4R2 PF09184.11 CDJ51262.1 - 0.82 9.2 9.9 1 8.9 9.9 1.2 1 0 0 1 1 1 0 PPP4R2 SLC12 PF03522.15 CDJ51262.1 - 0.83 8.6 13.9 1.2 8.1 13.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 AF-4 PF05110.13 CDJ51262.1 - 0.9 7.5 22.3 1.2 7.2 22.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GREB1 PF15782.5 CDJ51262.1 - 0.93 6.5 19.2 1.1 6.3 19.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 CDJ51262.1 - 1.9 7.6 10.5 2.5 7.2 10.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4045 PF13254.6 CDJ51262.1 - 2 8.0 16.7 2.6 7.6 16.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Pal1 PF08316.11 CDJ51262.1 - 2.4 8.9 12.9 4.5 8.0 11.5 2.1 2 1 1 3 3 3 0 Pal1 cell morphology protein eIF-3_zeta PF05091.12 CDJ51262.1 - 3.1 6.6 21.6 4.3 6.2 21.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ51262.1 - 3.4 5.8 26.7 4.4 5.4 26.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF5523 PF17661.1 CDJ51262.1 - 3.6 7.2 19.5 5.1 6.7 19.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) LAP1C PF05609.12 CDJ51262.1 - 4.5 6.2 22.2 6.3 5.8 22.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MAJIN PF15077.6 CDJ51262.1 - 6.7 6.4 17.4 13 5.5 16.8 1.7 1 1 1 2 2 2 0 Membrane-anchored junction protein Velvet PF11754.8 CDJ51262.1 - 7.3 6.4 19.3 16 5.3 19.3 1.6 1 1 0 1 1 1 0 Velvet factor RskA PF10099.9 CDJ51262.1 - 9.9 6.4 31.5 1e+02 3.1 30.7 2.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF3474 PF11960.8 CDJ51264.1 - 6.7 6.9 6.5 7.7 6.7 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Mif2_N PF15624.6 CDJ51264.1 - 8.2 7.1 17.4 9.1 7.0 17.4 1.0 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DDRGK PF09756.9 CDJ51265.1 - 0.038 13.6 23.6 0.042 13.4 23.6 1.1 1 0 0 1 1 1 0 DDRGK domain DUF3381 PF11861.8 CDJ51265.1 - 0.26 11.1 20.3 0.31 10.8 20.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Lin-8 PF03353.15 CDJ51265.1 - 0.29 10.7 36.9 0.42 10.1 36.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ51265.1 - 0.38 9.3 36.8 0.46 9.0 36.8 1.0 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 CDJ51265.1 - 0.44 8.3 24.9 0.53 8.0 24.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIA PF03153.13 CDJ51265.1 - 0.47 10.4 51.1 0.55 10.2 51.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 CDJ51265.1 - 0.9 8.3 25.6 1 8.0 25.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.6 CDJ51265.1 - 1.1 9.1 31.6 1.4 8.8 31.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Trypan_PARP PF05887.11 CDJ51265.1 - 1.4 8.9 9.2 1.7 8.6 9.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NST1 PF13945.6 CDJ51265.1 - 1.7 8.7 36.5 2.2 8.3 36.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator eIF-3_zeta PF05091.12 CDJ51265.1 - 1.8 7.4 25.4 1.9 7.4 25.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Plasmodium_Vir PF05795.11 CDJ51265.1 - 2.4 7.5 24.9 2.8 7.3 24.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Bud13 PF09736.9 CDJ51265.1 - 2.7 8.4 23.8 3.8 7.9 23.8 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Miga PF10265.9 CDJ51265.1 - 2.7 6.9 26.5 3.2 6.6 26.5 1.0 1 0 0 1 1 1 0 Mitoguardin DUF4746 PF15928.5 CDJ51265.1 - 3 7.2 21.7 3.5 7.0 21.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GREB1 PF15782.5 CDJ51265.1 - 3.1 4.8 39.0 3.7 4.6 39.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_U57 PF05582.12 CDJ51265.1 - 3.5 6.8 11.9 3.7 6.7 11.9 1.2 1 0 0 1 1 1 0 YabG peptidase U57 TRAP_alpha PF03896.16 CDJ51265.1 - 3.9 6.6 13.4 4.6 6.4 13.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3807 PF12720.7 CDJ51265.1 - 5.5 7.2 35.8 6.5 7.0 35.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Asp-B-Hydro_N PF05279.11 CDJ51265.1 - 6.4 6.8 20.9 6.7 6.7 20.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2828 PF11443.8 CDJ51265.1 - 8.2 4.4 19.7 8.6 4.3 19.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SPX PF03105.19 CDJ51265.1 - 9.2 6.1 42.0 11 5.8 42.0 1.0 1 0 0 1 1 1 0 SPX domain Tetraspanin PF00335.20 CDJ51266.1 - 0.00032 20.5 8.9 0.49 10.1 0.4 3.9 3 1 0 3 3 3 3 Tetraspanin family DUF2371 PF10177.9 CDJ51266.1 - 0.17 12.1 0.7 32 4.7 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) Neur_chan_memb PF02932.16 CDJ51266.1 - 0.82 9.7 0.0 0.82 9.7 0.0 4.5 5 0 0 5 5 5 0 Neurotransmitter-gated ion-channel transmembrane region RskA PF10099.9 CDJ51267.1 - 0.0011 19.2 4.0 0.0011 19.2 4.0 10.1 2 2 4 6 6 6 2 Anti-sigma-K factor rskA RRM_1 PF00076.22 CDJ51267.1 - 0.034 14.0 0.0 0.097 12.5 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.19 CDJ51267.1 - 9 6.1 67.3 0.036 14.0 16.8 4.0 1 1 0 2 2 2 0 SPX domain IMUP PF15761.5 CDJ51269.1 - 0.014 16.1 17.0 0.014 16.1 17.0 3.8 3 1 0 3 3 3 0 Immortalisation up-regulated protein Spore_YhcN_YlaJ PF09580.10 CDJ51269.1 - 0.028 14.5 0.2 0.028 14.5 0.2 4.1 3 2 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF677 PF05055.12 CDJ51269.1 - 0.24 10.2 5.2 0.73 8.7 5.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Utp14 PF04615.13 CDJ51269.1 - 0.42 9.1 35.9 9.7 4.6 35.9 2.5 1 1 0 1 1 1 0 Utp14 protein MAM33 PF02330.16 CDJ51269.1 - 0.73 9.7 29.3 1.1 9.2 1.5 4.5 4 0 0 4 4 4 0 Mitochondrial glycoprotein DUF2339 PF10101.9 CDJ51270.1 - 1e-06 27.7 13.4 1e-06 27.7 13.4 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2339) Presenilin PF01080.17 CDJ51270.1 - 0.0004 19.3 25.5 0.0004 19.3 25.5 4.2 3 1 0 3 3 3 2 Presenilin MDM10 PF12519.8 CDJ51270.1 - 0.0013 17.7 13.2 0.0013 17.7 13.2 3.8 3 1 0 3 3 3 1 Mitochondrial distribution and morphology protein 10 WBP-1 PF11669.8 CDJ51270.1 - 0.17 12.5 0.1 0.17 12.5 0.1 7.1 4 3 0 4 4 4 0 WW domain-binding protein 1 RskA PF10099.9 CDJ51271.1 - 0.02 15.2 0.2 0.02 15.2 0.2 3.1 2 1 0 2 2 2 0 Anti-sigma-K factor rskA TUSC2 PF15000.6 CDJ51272.1 - 0.26 11.6 0.0 0.5 10.7 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor candidate 2 Ribosomal_60s PF00428.19 CDJ51273.1 - 0.038 14.6 5.7 0.054 14.1 5.7 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein ASC PF00858.24 CDJ51273.1 - 4.3 6.2 13.3 5.2 5.9 13.3 1.3 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF4746 PF15928.5 CDJ51273.1 - 4.3 6.7 17.5 6.3 6.1 17.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3292 PF11696.8 CDJ51273.1 - 5.7 5.2 19.9 6.7 4.9 19.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) SLC12 PF03522.15 CDJ51273.1 - 6 5.8 31.8 7.3 5.5 31.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Spt20 PF12090.8 CDJ51274.1 - 0.0087 15.7 4.1 0.0087 15.7 4.1 11.8 4 2 3 10 10 10 2 Spt20 family BUD22 PF09073.10 CDJ51275.1 - 0.0019 17.6 8.5 0.0019 17.6 8.5 11.7 11 1 0 11 11 11 5 BUD22 EOS1 PF12326.8 CDJ51275.1 - 0.0038 17.2 0.1 0.0038 17.2 0.1 9.5 9 2 1 10 10 10 1 N-glycosylation protein BAF1_ABF1 PF04684.13 CDJ51276.1 - 0.02 14.0 20.5 0.023 13.8 20.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Auxin_canalis PF05703.11 CDJ51276.1 - 0.048 13.6 14.4 0.056 13.4 14.4 1.1 1 0 0 1 1 1 0 Auxin canalisation DUF3807 PF12720.7 CDJ51276.1 - 0.11 12.8 31.7 0.12 12.6 31.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Draxin PF15550.6 CDJ51276.1 - 0.34 10.8 16.0 0.39 10.6 16.0 1.0 1 0 0 1 1 1 0 Draxin DUF4366 PF14283.6 CDJ51276.1 - 0.37 10.8 10.6 0.5 10.4 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Cellulose_synt PF03552.14 CDJ51276.1 - 0.46 8.9 7.8 0.51 8.8 7.8 1.0 1 0 0 1 1 1 0 Cellulose synthase Lin-8 PF03353.15 CDJ51276.1 - 0.67 9.5 28.4 0.74 9.3 28.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DDRGK PF09756.9 CDJ51276.1 - 0.75 9.4 33.2 0.86 9.2 33.2 1.1 1 0 0 1 1 1 0 DDRGK domain Peptidase_S15 PF02129.18 CDJ51276.1 - 1.1 8.7 18.3 1.4 8.5 18.3 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3292 PF11696.8 CDJ51276.1 - 1.6 7.0 18.9 1.8 6.8 18.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF2052 PF09747.9 CDJ51276.1 - 1.8 8.6 24.2 2.1 8.4 24.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 CDJ51276.1 - 1.9 7.2 31.2 2.1 7.1 31.2 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CDJ51276.1 - 1.9 7.2 22.2 2 7.1 22.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIP PF07454.11 CDJ51276.1 - 2.1 7.8 23.9 2.9 7.3 23.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NST1 PF13945.6 CDJ51276.1 - 2.3 8.3 34.7 3 7.9 34.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator PA26 PF04636.13 CDJ51276.1 - 2.4 7.0 18.6 2.6 6.8 18.6 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CCSAP PF15748.5 CDJ51276.1 - 2.5 8.2 29.6 2.7 8.1 29.6 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PPL5 PF18168.1 CDJ51276.1 - 2.6 7.3 17.3 3 7.1 17.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 CobT PF06213.12 CDJ51276.1 - 2.6 7.4 32.5 3.6 6.9 32.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1387 PF07139.11 CDJ51276.1 - 2.8 7.6 24.1 3.3 7.3 24.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF2126 PF09899.9 CDJ51276.1 - 3.4 5.6 17.3 4 5.4 17.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) LptF_LptG PF03739.14 CDJ51276.1 - 3.5 6.4 8.0 3.8 6.2 8.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG RR_TM4-6 PF06459.12 CDJ51276.1 - 3.6 7.3 27.8 4.1 7.2 27.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ51276.1 - 3.6 5.8 24.2 4.1 5.6 24.2 1.0 1 0 0 1 1 1 0 CDC45-like protein eIF-3_zeta PF05091.12 CDJ51276.1 - 4.2 6.2 34.0 5 6.0 34.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ51276.1 - 4.4 6.2 26.9 5 6.0 26.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 CDJ51276.1 - 4.5 7.2 19.3 5.4 7.0 19.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF572 PF04502.13 CDJ51276.1 - 5.3 6.6 22.9 6.1 6.4 22.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Band_3_cyto PF07565.13 CDJ51276.1 - 5.3 6.8 23.6 6.7 6.4 23.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RPN2_C PF18004.1 CDJ51276.1 - 5.8 6.8 23.1 7.3 6.5 23.1 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 CDJ51276.1 - 6.2 6.2 18.2 8.1 5.8 18.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GREB1 PF15782.5 CDJ51276.1 - 6.3 3.8 26.8 7.1 3.6 26.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nop53 PF07767.11 CDJ51276.1 - 6.4 6.1 32.5 8.7 5.6 32.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Endostatin PF06482.11 CDJ51276.1 - 6.7 6.1 23.6 7.6 5.9 23.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin NARP1 PF12569.8 CDJ51276.1 - 6.8 5.5 23.0 7.9 5.3 23.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hid1 PF12722.7 CDJ51276.1 - 7.1 4.6 24.7 8.2 4.4 24.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF5427 PF10310.9 CDJ51276.1 - 7.5 5.4 28.3 8.7 5.2 28.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) VIT1 PF01988.19 CDJ51276.1 - 8.5 6.2 14.8 10 5.9 14.8 1.1 1 0 0 1 1 1 0 VIT family DUF913 PF06025.12 CDJ51276.1 - 9.5 5.1 17.2 11 4.9 17.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BORG_CEP PF14957.6 CDJ51276.1 - 9.8 7.4 18.5 12 7.1 18.5 1.2 1 0 0 1 1 1 0 Cdc42 effector HSP90 PF00183.18 CDJ51277.1 - 3.9e-232 771.7 49.4 1.3e-231 770.0 49.4 1.7 1 1 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CDJ51277.1 - 3.2e-16 59.8 0.0 6.1e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ51277.1 - 6.5e-10 39.0 0.1 2.5e-09 37.1 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 CDJ51277.1 - 0.021 14.9 1.1 0.055 13.5 0.2 2.2 2 0 0 2 2 2 0 Tumour suppressor protein Zip PF02535.22 CDJ51277.1 - 0.19 10.9 5.7 0.3 10.3 5.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ51277.1 - 0.79 8.4 11.9 1.3 7.7 11.9 1.3 1 0 0 1 1 1 0 Presenilin TRAP_alpha PF03896.16 CDJ51277.1 - 0.92 8.7 10.1 1.8 7.7 10.1 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cofac_haem_bdg PF04187.13 CDJ51277.1 - 0.92 9.4 4.3 0.53 10.2 0.1 2.6 2 1 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN CDC45 PF02724.14 CDJ51277.1 - 0.93 7.7 23.0 1.5 7.0 23.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ51277.1 - 4.3 7.1 29.2 0.1 12.4 22.0 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4228 PF14009.6 CDJ51277.1 - 4.9 7.5 8.2 11 6.3 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) RNA_pol_Rpc4 PF05132.14 CDJ51277.1 - 6.5 7.2 16.9 15 6.0 16.9 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ndc80_HEC PF03801.13 CDJ51279.1 - 1.2e-17 64.0 0.1 1.2e-17 64.0 0.1 4.1 3 2 0 3 3 3 1 HEC/Ndc80p family Exonuc_VII_L PF02601.15 CDJ51279.1 - 0.0061 16.2 1.7 0.0061 16.2 1.7 3.0 2 1 0 2 2 2 1 Exonuclease VII, large subunit RasGAP_C PF03836.15 CDJ51279.1 - 0.054 13.6 0.0 0.054 13.6 0.0 4.5 3 2 1 5 5 5 0 RasGAP C-terminus DUF2972 PF11186.8 CDJ51279.1 - 1 9.2 22.8 0.075 12.9 15.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) HMMR_N PF15905.5 CDJ51279.1 - 6.6 6.1 61.2 0.0098 15.4 12.4 2.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Ribosomal_60s PF00428.19 CDJ51279.1 - 7.9 7.1 13.7 2.4 8.8 8.6 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Mcm10 PF09332.11 CDJ51280.1 - 2.6e-10 40.3 6.9 2.6e-10 40.3 6.9 3.6 2 1 0 3 3 3 1 Mcm10 replication factor zf-primase PF09329.11 CDJ51280.1 - 1.5e-07 31.1 0.4 1.5e-07 31.1 0.4 2.6 3 0 0 3 3 3 1 Primase zinc finger RskA PF10099.9 CDJ51280.1 - 0.0068 16.7 16.4 0.0068 16.7 16.4 5.6 3 2 1 4 4 4 1 Anti-sigma-K factor rskA Jak1_Phl PF17887.1 CDJ51282.1 - 0.00084 19.3 8.2 0.00099 19.1 8.2 1.1 1 0 0 1 1 1 1 Jak1 pleckstrin homology-like domain LMBR1 PF04791.16 CDJ51282.1 - 0.059 12.3 4.5 0.065 12.1 4.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Toxin_31 PF08119.11 CDJ51282.1 - 0.065 13.0 0.3 0.09 12.5 0.3 1.2 1 0 0 1 1 1 0 Scorpion acidic alpha-KTx toxin family PIP5K PF01504.18 CDJ51282.1 - 0.075 12.2 8.3 0.077 12.2 8.3 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase ECH_2 PF16113.5 CDJ51282.1 - 0.14 11.6 5.4 0.14 11.6 5.4 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase TFIIA PF03153.13 CDJ51282.1 - 0.18 11.8 32.1 0.19 11.7 32.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAD-SLDH PF12318.8 CDJ51282.1 - 0.19 11.8 11.5 0.26 11.4 11.5 1.3 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase AIF_C PF14721.6 CDJ51282.1 - 0.23 11.8 8.1 0.25 11.7 8.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RR_TM4-6 PF06459.12 CDJ51282.1 - 0.31 10.8 9.0 0.3 10.9 9.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.10 CDJ51282.1 - 0.32 11.0 8.7 0.36 10.9 8.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pex14_N PF04695.13 CDJ51282.1 - 0.35 11.5 21.5 0.38 11.4 21.5 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peroxin-13_N PF04088.13 CDJ51282.1 - 0.36 11.1 5.4 0.38 11.0 5.4 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region EIIBC-GUT_N PF03612.14 CDJ51282.1 - 0.37 10.5 9.1 0.38 10.5 9.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus MecA PF05389.12 CDJ51282.1 - 0.37 10.4 9.4 0.39 10.3 9.4 1.0 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Peptidase_U4 PF03419.13 CDJ51282.1 - 0.52 9.6 4.9 0.62 9.3 4.9 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA RskA PF10099.9 CDJ51282.1 - 0.55 10.5 9.0 0.64 10.3 9.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Tim54 PF11711.8 CDJ51282.1 - 0.76 8.5 9.9 0.78 8.5 9.9 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 CDJ51282.1 - 0.8 9.4 7.9 0.82 9.4 7.9 1.0 1 0 0 1 1 1 0 Connexin SpoIIP PF07454.11 CDJ51282.1 - 0.98 8.8 12.5 1 8.7 12.5 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CrgA PF06781.12 CDJ51282.1 - 1.2 9.2 4.0 1.5 8.9 4.0 1.4 1 1 0 1 1 1 0 Cell division protein CrgA DUF2828 PF11443.8 CDJ51282.1 - 1.2 7.1 9.3 1.2 7.1 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DDE_Tnp_1_2 PF13586.6 CDJ51282.1 - 1.7 9.1 6.9 2 8.8 6.9 1.2 1 0 0 1 1 1 0 Transposase DDE domain Neur_chan_memb PF02932.16 CDJ51282.1 - 1.8 8.6 6.9 1.8 8.6 6.9 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DcuA_DcuB PF03605.14 CDJ51282.1 - 1.9 7.3 3.7 2 7.2 3.7 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter FAM60A PF15396.6 CDJ51282.1 - 2 8.3 9.0 2.3 8.2 9.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_U57 PF05582.12 CDJ51282.1 - 2.2 7.5 9.6 2.2 7.4 9.6 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF3371 PF11851.8 CDJ51282.1 - 2.2 9.4 14.3 2.6 9.2 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) CCDC53 PF10152.9 CDJ51282.1 - 2.3 8.6 12.8 2.5 8.5 12.8 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PepSY_TM PF03929.16 CDJ51282.1 - 2.6 7.6 8.1 2.6 7.6 8.1 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Asparaginase_2 PF01112.18 CDJ51282.1 - 2.6 7.0 8.4 2.6 7.0 8.4 1.0 1 0 0 1 1 1 0 Asparaginase CTU2 PF10288.9 CDJ51282.1 - 2.7 8.3 12.5 3.1 8.1 12.5 1.1 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 eIF-3_zeta PF05091.12 CDJ51282.1 - 2.7 6.8 18.1 3.1 6.7 18.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ51282.1 - 3 8.9 14.5 4.3 8.4 14.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ51282.1 - 3 6.7 30.4 3.4 6.5 30.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 CDJ51282.1 - 3.5 7.6 20.3 3.9 7.5 20.3 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EOS1 PF12326.8 CDJ51282.1 - 4.4 7.2 7.8 5 7.0 7.8 1.1 1 0 0 1 1 1 0 N-glycosylation protein DUF4199 PF13858.6 CDJ51282.1 - 4.5 7.7 6.9 4.8 7.6 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Ndc1_Nup PF09531.10 CDJ51282.1 - 4.7 5.8 9.5 4.9 5.7 9.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ctr PF04145.15 CDJ51282.1 - 4.9 7.8 6.4 5.3 7.6 6.4 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Ureide_permease PF07168.11 CDJ51282.1 - 5.2 5.7 7.1 5.9 5.5 7.1 1.0 1 0 0 1 1 1 0 Ureide permease DUF3984 PF13136.6 CDJ51282.1 - 5.4 6.3 11.5 6 6.2 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) ALMT PF11744.8 CDJ51282.1 - 5.7 5.7 8.3 5.8 5.6 8.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Activator_LAG-3 PF11498.8 CDJ51282.1 - 5.9 5.7 45.1 6.9 5.5 45.1 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CSG2 PF16965.5 CDJ51282.1 - 6.5 5.6 7.5 6.9 5.5 7.5 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Baculo_PP31 PF05311.11 CDJ51282.1 - 6.6 6.1 12.9 7.2 6.0 12.9 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Serinc PF03348.15 CDJ51282.1 - 6.6 5.5 9.5 7.4 5.4 9.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4400 PF14348.6 CDJ51282.1 - 7 6.1 6.1 8 5.9 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Rpp20 PF12328.8 CDJ51282.1 - 7.8 6.5 11.2 9.4 6.2 11.2 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Band_3_cyto PF07565.13 CDJ51282.1 - 8 6.2 12.1 8.8 6.0 12.1 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain EPL1 PF10513.9 CDJ51282.1 - 9 6.7 14.1 10 6.5 14.1 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like PAT1 PF09770.9 CDJ51282.1 - 9.2 4.4 23.1 9.3 4.4 23.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.17 CDJ51282.1 - 9.4 6.3 12.9 10 6.2 12.9 1.0 1 0 0 1 1 1 0 DDHD domain CLN3 PF02487.17 CDJ51282.1 - 9.5 5.1 9.9 10 5.1 9.9 1.0 1 0 0 1 1 1 0 CLN3 protein CPSF100_C PF13299.6 CDJ51282.1 - 9.7 6.3 11.3 11 6.1 11.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CDJ51282.1 - 9.7 4.8 16.0 10 4.8 16.0 1.0 1 0 0 1 1 1 0 Presenilin DUF2367 PF10164.9 CDJ51282.1 - 10 6.7 8.9 14 6.3 8.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Peptidase_M22 PF00814.25 CDJ51283.1 - 1.2e-65 222.0 1.7 1.6e-48 165.8 0.1 2.1 2 0 0 2 2 2 2 Glycoprotease family Arm-DNA-bind_4 PF14657.6 CDJ51283.1 - 0.022 14.5 0.6 0.022 14.5 0.6 2.1 2 0 0 2 2 2 0 Arm DNA-binding domain Macoilin PF09726.9 CDJ51283.1 - 0.1 11.1 4.7 0.18 10.3 4.7 1.3 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 CDJ51283.1 - 2.6 7.9 21.7 0.079 12.9 14.8 1.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal TCP PF03634.13 CDJ51283.1 - 5.6 7.5 13.8 2.1 8.9 10.5 2.0 2 0 0 2 2 2 0 TCP family transcription factor Presenilin PF01080.17 CDJ51283.1 - 7.4 5.2 9.0 13 4.4 9.0 1.4 1 0 0 1 1 1 0 Presenilin ATP-synt_C PF00137.21 CDJ51284.1 - 4.8e-26 90.9 34.1 4.4e-18 65.4 14.0 6.6 6 2 0 6 6 3 2 ATP synthase subunit C Utp14 PF04615.13 CDJ51284.1 - 8.5e-08 31.3 24.1 8.5e-08 31.3 24.1 3.1 2 1 1 3 3 3 2 Utp14 protein Acetyltransf_7 PF13508.7 CDJ51284.1 - 1.4e-05 25.5 0.2 5.2e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CLN3 PF02487.17 CDJ51284.1 - 0.00011 21.4 0.2 0.00011 21.4 0.2 3.9 4 1 0 4 4 3 1 CLN3 protein Acetyltransf_1 PF00583.25 CDJ51284.1 - 0.0014 18.9 0.0 0.0041 17.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4834 PF16118.5 CDJ51284.1 - 0.0023 18.9 9.6 0.0023 18.9 9.6 5.7 5 2 0 5 5 2 1 Domain of unknown function (DUF4834) SpoIIP PF07454.11 CDJ51284.1 - 0.0033 16.9 42.4 0.0058 16.1 6.2 3.7 3 0 0 3 3 3 2 Stage II sporulation protein P (SpoIIP) Pex14_N PF04695.13 CDJ51284.1 - 0.0035 18.0 16.2 0.0035 18.0 16.2 5.8 4 2 1 5 5 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.6 CDJ51284.1 - 0.0035 17.0 0.8 0.0035 17.0 0.8 5.5 6 1 0 6 6 4 1 FAM176 family PIP5K PF01504.18 CDJ51284.1 - 0.0055 16.0 5.9 0.0055 16.0 5.9 3.7 4 0 0 4 4 3 1 Phosphatidylinositol-4-phosphate 5-Kinase Acetyltransf_CG PF14542.6 CDJ51284.1 - 0.01 15.9 0.0 0.035 14.2 0.0 1.9 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Tetraspanin PF00335.20 CDJ51284.1 - 0.04 13.6 0.1 0.2 11.4 0.1 2.2 1 0 0 1 1 1 0 Tetraspanin family 7TM_GPCR_Srab PF10292.9 CDJ51284.1 - 0.11 11.4 0.9 0.32 9.9 0.9 1.7 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor DUF1980 PF09323.10 CDJ51284.1 - 0.11 12.4 0.1 0.11 12.4 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1980) PigN PF04987.14 CDJ51284.1 - 0.41 9.5 0.0 0.41 9.5 0.0 2.7 2 0 0 2 2 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF1772 PF08592.11 CDJ51284.1 - 0.58 10.5 0.0 0.58 10.5 0.0 7.3 5 3 3 8 8 5 0 Domain of unknown function (DUF1772) SARAF PF06682.12 CDJ51284.1 - 2.8 7.5 40.0 0.31 10.6 9.4 2.6 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SLC12 PF03522.15 CDJ51284.1 - 4.8 6.1 54.7 0.32 10.0 9.9 3.8 4 0 0 4 4 4 0 Solute carrier family 12 Mtc PF03820.17 CDJ51285.1 - 1.5e-12 47.2 0.1 2.2e-12 46.7 0.0 1.3 1 1 0 1 1 1 1 Tricarboxylate carrier Pex14_N PF04695.13 CDJ51285.1 - 0.00036 21.2 10.5 0.00045 20.9 10.5 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region bMG10 PF17973.1 CDJ51285.1 - 0.038 14.2 0.5 0.047 13.9 0.5 1.3 1 1 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain Spt20 PF12090.8 CDJ51285.1 - 0.094 12.3 19.0 0.09 12.4 19.0 1.2 1 0 0 1 1 1 0 Spt20 family DUF4258 PF14076.6 CDJ51285.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) Presenilin PF01080.17 CDJ51285.1 - 0.33 9.7 5.2 0.34 9.6 5.2 1.0 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 CDJ51285.1 - 1.1 9.0 7.9 1.2 8.9 7.9 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 CDJ51285.1 - 2.8 7.9 5.1 3 7.8 5.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1772 PF08592.11 CDJ51286.1 - 0.24 11.7 1.2 0.87 9.9 1.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) AhpC-TSA PF00578.21 CDJ51287.1 - 9e-35 119.3 0.0 1.1e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ51287.1 - 1.1e-15 57.7 0.0 1.3e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDJ51287.1 - 2.4e-13 49.7 0.3 5.5e-13 48.5 0.3 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin V_ATPase_I PF01496.19 CDJ51288.1 - 8.3 4.2 30.7 11 3.8 30.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Asp_protease_2 PF13650.6 CDJ51289.1 - 5.7e-09 36.5 0.0 1.5e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ51289.1 - 9.2e-08 32.6 0.0 2.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ51289.1 - 1.6e-05 24.7 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CDJ51289.1 - 0.0073 16.6 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ51289.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 CDJ51290.1 - 4.8e-27 93.9 0.0 7.8e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ51290.1 - 2.5e-20 72.9 0.0 4e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ51290.1 - 6.9e-20 71.3 0.0 1.3e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2722 PF10846.8 CDJ51293.1 - 0.0011 18.0 6.1 0.0011 18.0 6.1 11.8 4 2 3 7 7 7 1 Protein of unknown function (DUF2722) DUF3800 PF12686.7 CDJ51293.1 - 0.0035 18.0 0.0 2.7 8.6 0.0 4.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3800) MMR_HSR1_Xtn PF16897.5 CDJ51294.1 - 2e-40 137.1 0.1 3.3e-40 136.4 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CDJ51294.1 - 2.2e-22 78.9 0.0 7.6e-22 77.1 0.0 1.9 2 0 0 2 2 2 1 TGS domain SR-25 PF10500.9 CDJ51295.1 - 0.0071 16.0 10.9 0.0071 16.0 10.9 3.2 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein NicO PF03824.16 CDJ51295.1 - 0.72 9.1 8.9 0.83 8.9 8.9 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Spt20 PF12090.8 CDJ51296.1 - 0.0011 18.7 9.7 0.0011 18.7 9.7 5.2 4 1 0 5 5 5 1 Spt20 family Rxt3 PF08642.10 CDJ51296.1 - 0.0021 18.8 3.5 0.0021 18.8 3.5 3.5 4 1 1 5 5 5 2 Histone deacetylation protein Rxt3 AIF_C PF14721.6 CDJ51296.1 - 6.1 7.2 34.4 0.44 10.9 0.2 4.5 4 0 0 4 4 4 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Syntaxin PF00804.25 CDJ51298.1 - 0.029 14.0 12.5 0.038 13.7 12.5 1.1 1 0 0 1 1 1 0 Syntaxin DUF3682 PF12446.8 CDJ51299.1 - 0.088 13.3 9.8 0.17 12.4 9.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) Ribosomal_60s PF00428.19 CDJ51299.1 - 0.16 12.6 11.8 0.35 11.5 11.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Androgen_recep PF02166.16 CDJ51299.1 - 3.6 6.3 16.6 0.2 10.5 3.7 2.1 2 0 0 2 2 2 0 Androgen receptor ETRAMP PF09716.10 CDJ51300.1 - 2.2 8.4 12.3 0.49 10.5 1.0 3.8 2 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Dehydrin PF00257.19 CDJ51301.1 - 0.011 16.3 5.7 0.011 16.3 5.7 2.3 2 0 0 2 2 2 0 Dehydrin AIMP2_LysRS_bd PF16780.5 CDJ51301.1 - 1.5 8.6 4.0 43 3.9 1.7 3.0 2 1 0 2 2 2 0 AIMP2 lysyl-tRNA synthetase binding domain DUF5427 PF10310.9 CDJ51301.1 - 1.7 7.5 7.8 1.9 7.3 7.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) TFIIA PF03153.13 CDJ51302.1 - 0.46 10.4 27.9 0.65 9.9 27.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ51302.1 - 2.6 7.0 10.0 3.2 6.7 10.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Exonuc_VII_L PF02601.15 CDJ51302.1 - 2.8 7.4 14.8 3.7 7.0 14.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit WDCP PF15390.6 CDJ51302.1 - 7.2 4.9 14.9 9.1 4.5 14.9 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family RskA PF10099.9 CDJ51302.1 - 8.2 6.7 39.0 0.026 14.8 17.9 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA MAT1 PF06391.13 CDJ51302.1 - 8.2 6.2 13.5 14 5.4 13.5 1.5 1 1 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Hamartin PF04388.12 CDJ51302.1 - 9.2 4.8 24.0 13 4.3 24.0 1.1 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 CDJ51303.1 - 3.9e-07 29.7 0.0 3.9e-07 29.7 0.0 4.7 5 0 0 5 5 5 1 Protein kinase domain DUF2722 PF10846.8 CDJ51303.1 - 0.001 18.2 10.3 0.001 18.2 10.3 18.1 11 5 2 13 13 13 3 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ51304.1 - 0.13 11.8 33.4 0.14 11.7 33.4 1.0 1 0 0 1 1 1 0 Spt20 family Ureide_permease PF07168.11 CDJ51304.1 - 0.27 10.0 7.2 0.3 9.8 7.2 1.0 1 0 0 1 1 1 0 Ureide permease INSIG PF07281.12 CDJ51304.1 - 0.32 10.6 5.2 0.38 10.4 5.2 1.1 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) DUF2802 PF10975.8 CDJ51304.1 - 0.45 10.7 18.2 0.56 10.4 18.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Pex14_N PF04695.13 CDJ51304.1 - 0.54 10.9 18.4 0.57 10.8 18.4 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 CDJ51304.1 - 0.67 8.8 28.6 0.69 8.8 28.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ51304.1 - 0.82 10.0 13.1 0.91 9.9 13.1 1.0 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF3391 PF11871.8 CDJ51304.1 - 1.1 9.8 12.7 1.2 9.7 12.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) SpoIIP PF07454.11 CDJ51304.1 - 1.7 8.0 11.5 1.8 8.0 11.5 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Med15 PF09606.10 CDJ51304.1 - 1.8 7.2 29.1 1.7 7.2 29.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sarcoglycan_2 PF05510.13 CDJ51304.1 - 1.8 7.2 9.1 1.9 7.2 9.1 1.0 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF775 PF05603.12 CDJ51304.1 - 1.8 8.0 13.1 1.8 8.1 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) CobT PF06213.12 CDJ51304.1 - 2 7.7 16.7 2 7.8 16.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Suf PF05843.14 CDJ51304.1 - 2.1 8.2 18.0 2.3 8.1 18.0 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 CDJ51304.1 - 2.2 9.3 14.1 2.5 9.1 14.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Folate_carrier PF01770.18 CDJ51304.1 - 2.4 6.8 8.1 2.3 6.8 8.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier EIIBC-GUT_N PF03612.14 CDJ51304.1 - 2.4 7.8 10.8 2.6 7.7 10.8 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Orf78 PF06024.12 CDJ51304.1 - 2.5 8.5 7.4 2.8 8.3 7.4 1.1 1 0 0 1 1 1 0 Orf78 (ac78) TFIIA PF03153.13 CDJ51304.1 - 2.5 8.0 31.3 2.6 7.9 31.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AIF_C PF14721.6 CDJ51304.1 - 3.2 8.1 9.6 3.4 8.0 9.6 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FlaG PF03646.15 CDJ51304.1 - 3.3 7.9 17.0 3.8 7.7 17.0 1.2 1 0 0 1 1 1 0 FlaG protein DUF853 PF05872.12 CDJ51304.1 - 3.3 6.2 10.1 3.3 6.2 10.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TERB2 PF15101.6 CDJ51304.1 - 3.4 7.7 19.2 3.5 7.6 19.2 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 UPF0560 PF10577.9 CDJ51304.1 - 3.6 6.0 21.1 3.8 5.9 21.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2126 PF09899.9 CDJ51304.1 - 5.5 4.9 11.1 5.3 5.0 11.1 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Spore_coat_CotO PF14153.6 CDJ51304.1 - 5.5 6.9 17.4 5.6 6.8 17.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Coilin_N PF15862.5 CDJ51304.1 - 5.8 6.7 16.4 6.9 6.5 16.4 1.1 1 0 0 1 1 1 0 Coilin N-terminus CPSF100_C PF13299.6 CDJ51304.1 - 6.3 7.0 10.4 6.2 7.0 10.4 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S49_N PF08496.10 CDJ51304.1 - 6.4 6.8 11.1 6.3 6.8 11.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.12 CDJ51304.1 - 6.7 6.4 12.3 6.3 6.5 12.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.13 CDJ51304.1 - 7.1 6.4 12.2 7.5 6.3 12.2 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3464 PF11947.8 CDJ51304.1 - 7.1 6.4 13.5 7.9 6.2 13.5 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PigN PF04987.14 CDJ51304.1 - 8 5.2 8.6 8.4 5.1 8.6 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Mem_trans PF03547.18 CDJ51304.1 - 9.3 4.5 5.5 9.3 4.5 5.5 1.0 1 0 0 1 1 1 0 Membrane transport protein Pkinase PF00069.25 CDJ51305.1 - 1.6e-58 198.2 0.0 2.1e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ51305.1 - 3.3e-29 101.9 0.0 4.6e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ51305.1 - 6.3e-07 29.0 0.0 1.2e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDJ51305.1 - 0.022 14.3 0.3 0.049 13.2 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Jiraiya PF15038.6 CDJ51306.1 - 1 8.8 8.5 0.58 9.6 0.1 3.2 3 0 0 3 3 3 0 Jiraiya PEARLI-4 PF05278.12 CDJ51306.1 - 1.5 8.3 11.5 0.73 9.4 0.8 2.5 1 1 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Tup_N PF08581.10 CDJ51308.1 - 4.3 7.7 13.8 0.31 11.4 3.0 2.7 2 0 0 2 2 2 0 Tup N-terminal Med19 PF10278.9 CDJ51309.1 - 0.026 14.5 27.8 0.035 14.0 27.8 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CCDC106 PF15794.5 CDJ51309.1 - 0.052 13.3 19.5 0.062 13.0 19.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 EOS1 PF12326.8 CDJ51309.1 - 0.09 12.7 6.6 0.11 12.5 6.6 1.1 1 0 0 1 1 1 0 N-glycosylation protein Dehydrin PF00257.19 CDJ51309.1 - 0.14 12.7 14.3 0.14 12.7 14.3 1.1 1 0 0 1 1 1 0 Dehydrin Vfa1 PF08432.10 CDJ51309.1 - 0.51 10.6 25.6 0.63 10.3 25.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3807 PF12720.7 CDJ51309.1 - 0.91 9.8 22.5 1.1 9.6 22.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) GAGA_bind PF06217.12 CDJ51309.1 - 1.1 9.5 15.3 1.3 9.3 15.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2828 PF11443.8 CDJ51309.1 - 1.7 6.7 15.6 1.8 6.6 15.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RR_TM4-6 PF06459.12 CDJ51309.1 - 2.1 8.1 20.3 2.3 8.0 20.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ51309.1 - 2.3 7.1 10.4 2.5 7.0 10.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Rubella_Capsid PF05750.11 CDJ51309.1 - 2.8 7.5 5.7 3.2 7.3 5.7 1.0 1 0 0 1 1 1 0 Rubella capsid protein Dsh_C PF12316.8 CDJ51309.1 - 2.8 8.3 10.4 3.2 8.1 10.4 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SR-25 PF10500.9 CDJ51309.1 - 3.9 7.0 39.5 6.7 6.3 39.5 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein MCM_bind PF09739.9 CDJ51309.1 - 5.2 5.4 15.6 5.6 5.3 15.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4614 PF15391.6 CDJ51309.1 - 5.3 7.0 16.9 6.1 6.8 16.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CDC45 PF02724.14 CDJ51309.1 - 5.6 5.1 22.6 6.2 5.0 22.6 1.0 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 CDJ51309.1 - 6.1 5.5 19.2 6.9 5.3 19.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 CDJ51309.1 - 6.8 5.8 11.7 7.8 5.6 11.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3827 PF12877.7 CDJ51309.1 - 7.6 4.8 15.5 7.4 4.8 15.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MID_MedPIWI PF18296.1 CDJ51309.1 - 8 6.2 12.4 9.3 6.0 12.4 1.1 1 0 0 1 1 1 0 MID domain of medPIWI Lipase_3 PF01764.25 CDJ51310.1 - 4.9e-12 45.9 0.0 8.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Voldacs PF03517.13 CDJ51311.1 - 5.3e-25 88.2 0.0 7.1e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling RMI1_N PF08585.12 CDJ51312.1 - 2.6e-16 60.0 0.0 3.5e-15 56.4 0.0 2.3 1 1 0 1 1 1 1 RecQ mediated genome instability protein Coatomer_WDAD PF04053.14 CDJ51313.1 - 0.00014 21.0 7.9 0.002 17.3 0.6 3.3 5 0 0 5 5 5 2 Coatomer WD associated region ANAPC4_WD40 PF12894.7 CDJ51313.1 - 0.0066 16.7 0.0 3.9 7.8 0.1 4.1 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ51313.1 - 0.0093 16.8 0.2 53 4.9 0.0 5.5 6 0 0 6 6 6 0 WD domain, G-beta repeat PQQ PF01011.21 CDJ51313.1 - 0.037 14.0 0.1 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat ubiquitin PF00240.23 CDJ51314.1 - 5.1e-05 23.0 0.0 0.00015 21.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family DUF4131 PF13567.6 CDJ51314.1 - 0.26 10.9 4.1 0.41 10.3 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SPX PF03105.19 CDJ51315.1 - 0.61 9.9 4.5 0.83 9.5 4.5 1.2 1 0 0 1 1 1 0 SPX domain AhpC-TSA PF00578.21 CDJ51317.1 - 2e-28 98.8 0.0 2.6e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ51317.1 - 4.9e-12 45.8 0.0 6.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDJ51317.1 - 2.4e-10 40.1 0.2 4e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 CDJ51317.1 - 0.0065 16.6 0.0 0.0087 16.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme GSHPx PF00255.19 CDJ51317.1 - 0.034 13.7 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione peroxidase Ribosomal_S4e PF00900.20 CDJ51317.1 - 0.11 12.4 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 Ribosomal family S4e DMRT-like PF15791.5 CDJ51318.1 - 0.063 13.7 1.2 0.24 11.8 1.2 2.0 1 0 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 DUF2188 PF09954.9 CDJ51318.1 - 0.67 10.1 4.7 4.6 7.5 0.7 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) SR-25 PF10500.9 CDJ51319.1 - 2.4e-06 27.3 25.2 1.3e-05 25.0 20.3 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 CDJ51319.1 - 0.044 13.8 23.3 0.059 13.4 15.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) TFIIA PF03153.13 CDJ51319.1 - 0.12 12.4 17.4 0.19 11.7 17.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC106 PF15794.5 CDJ51319.1 - 1.9 8.1 26.0 0.46 10.1 16.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF3807 PF12720.7 CDJ51319.1 - 2.4 8.4 15.2 1.3 9.2 7.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF2072 PF09845.9 CDJ51319.1 - 5.1 7.4 15.9 0.082 13.2 3.9 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein DUF2052 PF09747.9 CDJ51319.1 - 6.2 6.9 18.4 3.3 7.8 3.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TFIIA PF03153.13 CDJ51320.1 - 0.00042 20.4 42.0 0.00053 20.1 42.0 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ51320.1 - 0.00074 19.2 24.5 0.001 18.7 24.5 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Macoilin PF09726.9 CDJ51320.1 - 0.0062 15.2 28.0 0.0082 14.8 28.0 1.1 1 0 0 1 1 1 1 Macoilin family MAP7 PF05672.11 CDJ51320.1 - 0.03 14.0 19.3 0.046 13.4 19.3 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family ATF7IP_BD PF16788.5 CDJ51320.1 - 0.29 11.2 25.4 0.41 10.7 25.4 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain Asp-B-Hydro_N PF05279.11 CDJ51320.1 - 0.44 10.6 12.5 0.54 10.3 12.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region OmpH PF03938.14 CDJ51320.1 - 0.72 10.2 23.6 1 9.7 23.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PNISR PF15996.5 CDJ51320.1 - 1.1 9.4 29.6 2 8.6 29.6 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CytochromB561_N PF09786.9 CDJ51320.1 - 1.3 7.9 19.5 1.5 7.7 19.5 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Med15 PF09606.10 CDJ51320.1 - 1.8 7.2 35.2 2.2 6.9 35.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SLC12 PF03522.15 CDJ51320.1 - 2.1 7.3 19.8 2.7 6.9 19.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Tic110 PF16940.5 CDJ51320.1 - 2.3 6.6 11.3 2.9 6.3 11.3 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter MAP65_ASE1 PF03999.12 CDJ51320.1 - 4.3 5.9 26.2 4.9 5.7 26.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Myc_N PF01056.18 CDJ51320.1 - 4.3 7.1 22.2 5.7 6.7 22.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region SPX PF03105.19 CDJ51320.1 - 4.9 7.0 27.6 7.1 6.4 27.6 1.3 1 0 0 1 1 1 0 SPX domain V_ATPase_I PF01496.19 CDJ51320.1 - 4.9 5.0 15.5 6.4 4.6 15.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Draxin PF15550.6 CDJ51320.1 - 5.8 6.7 20.2 7.5 6.3 20.2 1.1 1 0 0 1 1 1 0 Draxin Ndc1_Nup PF09531.10 CDJ51320.1 - 5.9 5.5 22.7 7.2 5.2 22.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MMR1 PF08505.10 CDJ51320.1 - 9.7 6.4 33.8 12 6.1 33.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PRIMA1 PF16101.5 CDJ51321.1 - 0.3 11.1 5.1 0.73 9.9 5.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PmbA_TldD PF01523.16 CDJ51321.1 - 0.55 10.0 4.0 0.66 9.8 4.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DEC-1_N PF04625.13 CDJ51321.1 - 0.62 9.0 13.5 0.76 8.7 13.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Dehydrin PF00257.19 CDJ51321.1 - 2.7 8.5 17.8 3.1 8.3 6.8 2.2 2 0 0 2 2 2 0 Dehydrin SARG PF15385.6 CDJ51321.1 - 3.1 6.9 13.3 4.3 6.4 13.3 1.2 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein SARAF PF06682.12 CDJ51322.1 - 0.00033 20.4 3.6 0.00033 20.4 3.6 4.0 1 1 1 3 3 3 2 SOCE-associated regulatory factor of calcium homoeostasis Conotoxin PF02950.17 CDJ51322.1 - 0.034 15.1 2.3 0.034 15.1 2.3 7.6 5 3 3 8 8 8 0 Conotoxin GRP PF07172.11 CDJ51322.1 - 0.098 13.4 0.2 0.098 13.4 0.2 4.4 5 0 0 5 5 5 0 Glycine rich protein family DUF2434 PF10361.9 CDJ51322.1 - 0.33 9.9 2.7 1.2 8.1 2.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) TAS2R PF05296.13 CDJ51322.1 - 1.3 8.1 8.8 2.2 7.3 8.8 1.3 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) DUF2052 PF09747.9 CDJ51322.1 - 1.9 8.6 53.4 0.82 9.8 5.6 4.3 4 0 0 4 4 4 0 Coiled-coil domain containing protein (DUF2052) Halogen_Hydrol PF10112.9 CDJ51323.1 - 0.011 15.8 2.4 0.011 15.8 2.4 2.5 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein RskA PF10099.9 CDJ51323.1 - 0.61 10.4 25.3 2.7e+02 1.7 25.3 2.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA LMBR1 PF04791.16 CDJ51323.1 - 1.1 8.1 8.4 1.6 7.6 8.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Menin PF05053.13 CDJ51323.1 - 1.9 6.7 23.8 2.5 6.3 23.8 1.1 1 0 0 1 1 1 0 Menin GET2 PF08690.10 CDJ51323.1 - 4.4 6.9 29.5 0.11 12.2 13.9 2.1 1 1 1 2 2 2 0 GET complex subunit GET2 V_ATPase_I PF01496.19 CDJ51323.1 - 7.5 4.3 24.6 14 3.4 24.2 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ51324.1 - 0.0064 16.5 34.9 0.0073 16.3 34.9 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RNA_polI_A34 PF08208.11 CDJ51324.1 - 0.0078 16.3 30.3 0.0094 16.1 30.3 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF755 PF05501.11 CDJ51324.1 - 0.0099 16.1 29.6 0.0099 16.1 29.6 3.1 2 1 1 3 3 2 1 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ51324.1 - 0.022 14.4 55.8 0.69 9.5 55.8 2.1 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein NTP_transf_2 PF01909.23 CDJ51324.1 - 0.034 14.4 0.4 0.063 13.6 0.1 1.6 2 0 0 2 2 2 0 Nucleotidyltransferase domain SRP-alpha_N PF04086.13 CDJ51324.1 - 0.11 12.4 32.1 0.14 12.0 32.1 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CCDC24 PF15669.5 CDJ51324.1 - 0.35 10.7 16.2 0.17 11.8 14.1 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family XRCC4 PF06632.12 CDJ51324.1 - 0.36 9.6 24.6 0.47 9.2 24.6 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Roughex PF06020.11 CDJ51324.1 - 2.2 7.3 12.5 2.6 7.1 12.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TMEM51 PF15345.6 CDJ51324.1 - 3.6 7.4 21.9 4.7 7.0 21.9 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 CDK2AP PF09806.9 CDJ51324.1 - 4.8 7.2 29.2 2 8.5 26.5 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Macoilin PF09726.9 CDJ51324.1 - 5.9 5.3 30.6 7.2 5.0 30.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF4131 PF13567.6 CDJ51326.1 - 0.007 16.0 5.8 0.051 13.2 1.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) RskA PF10099.9 CDJ51326.1 - 0.085 13.1 78.6 2.2 8.5 38.4 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF1387 PF07139.11 CDJ51326.1 - 0.14 11.8 21.2 0.19 11.4 21.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Tau95_N PF17682.1 CDJ51326.1 - 0.16 12.2 7.6 1 9.6 0.2 2.2 2 0 0 2 2 2 0 Tau95 Triple barrel domain AFT PF08731.11 CDJ51326.1 - 0.22 12.0 8.7 1.7 9.1 1.4 2.2 2 0 0 2 2 2 0 Transcription factor AFT EIF4E-T PF10477.9 CDJ51326.1 - 0.3 9.8 31.3 0.43 9.4 31.3 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E SAGA-Tad1 PF12767.7 CDJ51326.1 - 0.82 9.4 15.8 1.3 8.8 15.8 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Cytochrom_C_asm PF01578.20 CDJ51326.1 - 0.97 9.2 4.3 3.3 7.4 0.6 2.2 2 0 0 2 2 2 0 Cytochrome C assembly protein CD20 PF04103.15 CDJ51326.1 - 1.2 9.2 7.6 0.13 12.4 0.7 2.2 1 1 1 2 2 2 0 CD20-like family DUF3408 PF11888.8 CDJ51326.1 - 1.2 9.2 20.4 1.1 9.4 9.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) NPR1_interact PF15699.5 CDJ51326.1 - 1.3 9.7 18.6 1.8 9.2 7.5 2.3 2 0 0 2 2 2 0 NPR1 interacting NEMP PF10225.9 CDJ51326.1 - 2.3 7.9 15.3 2 8.0 0.6 2.1 1 1 1 2 2 2 0 NEMP family DUF3357 PF11837.8 CDJ51326.1 - 2.8 8.4 26.7 4.4 7.8 12.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF4834 PF16118.5 CDJ51326.1 - 5.4 8.0 27.1 12 6.9 7.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ51326.1 - 5.6 6.5 67.0 0.089 12.4 14.4 2.2 2 0 0 2 2 2 0 Spt20 family SART-1 PF03343.13 CDJ51326.1 - 6.2 5.3 26.7 8 4.9 26.7 1.2 1 0 0 1 1 1 0 SART-1 family PRC2_HTH_1 PF18118.1 CDJ51326.1 - 9.1 7.2 13.9 17 6.3 1.2 2.3 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Connexin PF00029.19 CDJ51327.1 - 0.0082 15.9 2.9 0.0086 15.9 2.9 1.1 1 0 0 1 1 1 1 Connexin Pex14_N PF04695.13 CDJ51327.1 - 0.0096 16.6 10.3 0.01 16.5 10.3 1.0 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CSG2 PF16965.5 CDJ51327.1 - 0.016 14.2 4.2 0.016 14.2 4.2 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator HCO3_cotransp PF00955.21 CDJ51327.1 - 0.029 13.2 3.1 0.029 13.2 3.1 1.0 1 0 0 1 1 1 0 HCO3- transporter family Sarcoglycan_2 PF05510.13 CDJ51327.1 - 0.034 12.9 3.4 0.039 12.7 3.4 1.0 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Kei1 PF08552.11 CDJ51327.1 - 0.035 14.0 0.4 0.04 13.8 0.4 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 NARP1 PF12569.8 CDJ51327.1 - 0.06 12.3 13.4 0.064 12.2 13.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4407 PF14362.6 CDJ51327.1 - 0.067 12.5 9.8 0.094 12.1 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CLN3 PF02487.17 CDJ51327.1 - 0.079 12.0 6.1 0.087 11.9 6.1 1.0 1 0 0 1 1 1 0 CLN3 protein Med26_C PF15693.5 CDJ51327.1 - 0.079 13.1 16.7 0.089 12.9 16.7 1.0 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal Scs3p PF10261.9 CDJ51327.1 - 0.083 12.4 3.7 0.086 12.3 3.7 1.0 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM OATP PF03137.20 CDJ51327.1 - 0.15 10.3 2.9 0.17 10.2 2.9 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ureide_permease PF07168.11 CDJ51327.1 - 0.2 10.4 1.0 0.17 10.6 1.0 1.0 1 0 0 1 1 1 0 Ureide permease ALMT PF11744.8 CDJ51327.1 - 0.4 9.5 5.5 0.39 9.5 5.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Pex26 PF07163.12 CDJ51327.1 - 0.49 9.7 16.0 0.52 9.6 16.0 1.0 1 0 0 1 1 1 0 Pex26 protein Fig1 PF12351.8 CDJ51327.1 - 0.53 10.2 2.4 0.67 9.9 2.4 1.2 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Zip PF02535.22 CDJ51327.1 - 0.56 9.4 2.8 0.59 9.3 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CDJ51327.1 - 0.59 10.2 4.2 0.6 10.1 4.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ctr PF04145.15 CDJ51327.1 - 0.92 10.1 5.2 0.98 10.0 5.2 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DDHD PF02862.17 CDJ51327.1 - 0.93 9.6 6.3 0.93 9.6 6.3 1.1 1 0 0 1 1 1 0 DDHD domain MTP18 PF10558.9 CDJ51327.1 - 0.99 9.3 5.1 1.2 9.0 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Allantoicase PF03561.15 CDJ51327.1 - 1.1 9.2 6.0 1.2 9.1 6.0 1.1 1 0 0 1 1 1 0 Allantoicase repeat Suf PF05843.14 CDJ51327.1 - 1.5 8.7 11.6 1.9 8.4 11.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Folliculin PF11704.8 CDJ51327.1 - 1.6 8.6 7.0 1.7 8.5 7.0 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport SID-1_RNA_chan PF13965.6 CDJ51327.1 - 1.7 7.0 4.7 1.7 7.0 4.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SpoIIP PF07454.11 CDJ51327.1 - 1.7 8.1 13.0 1.8 8.0 13.0 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) LMBR1 PF04791.16 CDJ51327.1 - 1.8 7.4 7.9 2 7.2 7.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein MscS_TM PF12794.7 CDJ51327.1 - 2.1 7.2 13.0 2.9 6.7 13.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2722 PF10846.8 CDJ51327.1 - 2.2 7.1 26.6 2.4 7.0 26.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Gti1_Pac2 PF09729.9 CDJ51327.1 - 2.5 8.2 9.6 2.8 8.0 9.6 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family EMC3_TMCO1 PF01956.16 CDJ51327.1 - 3.1 7.5 10.0 3.3 7.4 10.0 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RR_TM4-6 PF06459.12 CDJ51327.1 - 3.3 7.4 14.1 3.9 7.2 14.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4637 PF15470.6 CDJ51327.1 - 7 6.4 10.5 8.8 6.0 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) VIT1 PF01988.19 CDJ51327.1 - 8.8 6.1 7.6 9.9 6.0 7.6 1.1 1 0 0 1 1 1 0 VIT family zf-RING_2 PF13639.6 CDJ51328.1 - 4.6e-08 33.3 2.1 4.6e-08 33.3 2.1 1.6 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 CDJ51328.1 - 2.8e-07 30.7 2.9 9.4e-07 29.0 2.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ51328.1 - 1.1e-05 25.2 1.0 1.1e-05 25.2 1.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ51328.1 - 1.4e-05 24.8 3.6 2.8e-05 23.8 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ51328.1 - 0.00012 21.8 1.9 0.00012 21.8 1.9 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CDJ51328.1 - 0.00089 19.3 1.4 0.0022 18.0 1.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SPX PF03105.19 CDJ51328.1 - 0.0013 18.7 10.5 0.0013 18.7 10.5 2.4 1 1 1 2 2 1 1 SPX domain zf-RING_5 PF14634.6 CDJ51328.1 - 0.0019 18.1 1.1 0.0019 18.1 1.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CDJ51328.1 - 0.0037 16.9 1.5 0.0075 15.9 1.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CDJ51328.1 - 0.0077 16.1 3.7 0.056 13.3 1.1 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 DUF4407 PF14362.6 CDJ51328.1 - 0.044 13.1 12.0 0.074 12.4 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 CDJ51328.1 - 0.12 11.3 21.6 0.15 11.0 21.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RINGv PF12906.7 CDJ51328.1 - 0.2 11.8 1.4 0.45 10.7 1.4 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.6 CDJ51328.1 - 0.59 10.2 8.4 0.11 12.6 3.6 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ51328.1 - 1.1 9.4 3.4 0.54 10.5 0.4 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Sec62 PF03839.16 CDJ51328.1 - 1.8 8.1 8.5 3.4 7.1 8.5 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 SLC12 PF03522.15 CDJ51328.1 - 1.9 7.5 18.5 1.7e+02 1.0 23.4 1.7 2 0 0 2 2 2 0 Solute carrier family 12 GREB1 PF15782.5 CDJ51328.1 - 2 5.4 33.1 3.9 4.5 33.1 1.4 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ51328.1 - 3.1 6.0 30.7 3.8 5.7 30.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C3HC4_3 PF13920.6 CDJ51328.1 - 3.1 7.7 5.5 0.34 10.8 1.1 1.6 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) ERCC4 PF02732.15 CDJ51329.1 - 3.1e-13 50.2 0.0 3.1e-13 50.2 0.0 5.0 5 1 0 5 5 5 1 ERCC4 domain TAF4 PF05236.14 CDJ51329.1 - 0.0011 18.8 17.1 0.0011 18.8 17.1 8.1 7 2 1 8 8 8 1 Transcription initiation factor TFIID component TAF4 family Macoilin PF09726.9 CDJ51329.1 - 0.0023 16.6 11.3 0.0023 16.6 11.3 5.6 4 1 0 5 5 5 1 Macoilin family Actin PF00022.19 CDJ51330.1 - 1.5e-36 126.0 2.0 1.3e-35 122.8 0.0 3.0 2 1 0 2 2 2 1 Actin DUF1676 PF07898.13 CDJ51330.1 - 0.53 10.3 0.0 0.53 10.3 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1676) SPX PF03105.19 CDJ51331.1 - 0.0049 16.8 0.0 0.0049 16.8 0.0 4.3 3 2 0 3 3 3 1 SPX domain SR-25 PF10500.9 CDJ51332.1 - 0.00038 20.1 11.5 0.00038 20.1 11.5 10.2 9 1 1 10 10 10 2 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 CDJ51332.1 - 0.0011 18.4 14.6 0.0011 18.4 14.6 7.3 5 3 1 6 6 6 1 BUD22 Zip PF02535.22 CDJ51332.1 - 0.002 17.4 5.0 0.002 17.4 5.0 8.2 6 3 2 8 8 8 2 ZIP Zinc transporter DUF4834 PF16118.5 CDJ51332.1 - 0.0027 18.6 2.6 0.0027 18.6 2.6 17.0 11 5 2 13 13 13 1 Domain of unknown function (DUF4834) AIF_C PF14721.6 CDJ51332.1 - 0.0042 17.4 1.5 0.0042 17.4 1.5 13.8 9 4 0 10 10 10 1 Apoptosis-inducing factor, mitochondrion-associated, C-term RskA PF10099.9 CDJ51332.1 - 0.013 15.8 0.8 0.013 15.8 0.8 16.4 3 3 10 13 13 13 0 Anti-sigma-K factor rskA Cohesin_HEAT PF12765.7 CDJ51332.1 - 0.13 12.5 2.5 0.37 11.1 1.2 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion TssO PF17561.2 CDJ51333.1 - 0.028 14.5 0.4 0.044 13.9 0.4 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO IgaA PF07095.11 CDJ51333.1 - 0.075 11.0 0.3 0.13 10.3 0.3 1.3 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DUF5313 PF17240.2 CDJ51333.1 - 0.24 11.8 0.2 0.24 11.8 0.2 1.9 3 0 0 3 3 3 0 Family of unknown function (DUF5313) Spt20 PF12090.8 CDJ51333.1 - 0.25 10.9 4.8 0.36 10.4 4.8 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ51333.1 - 0.31 9.9 2.5 0.46 9.4 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TraT PF05818.12 CDJ51333.1 - 0.72 9.5 9.4 0.075 12.7 4.4 1.9 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein NMN_transporter PF04973.12 CDJ51334.1 - 0.093 12.7 3.1 0.25 11.3 1.4 2.1 1 1 0 2 2 2 0 Nicotinamide mononucleotide transporter OATP PF03137.20 CDJ51334.1 - 0.37 9.0 8.0 0.16 10.3 1.0 2.8 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pyr_redox_2 PF07992.14 CDJ51335.1 - 0.00051 19.4 0.2 0.074 12.3 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TFIIA PF03153.13 CDJ51335.1 - 0.001 19.2 22.8 0.001 19.2 22.8 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PIP5K PF01504.18 CDJ51335.1 - 0.0091 15.3 5.5 0.059 12.6 0.2 2.1 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase NAD_binding_9 PF13454.6 CDJ51335.1 - 0.025 14.6 0.1 0.025 14.6 0.1 2.8 2 1 1 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CDJ51335.1 - 0.052 13.8 0.0 0.052 13.8 0.0 2.8 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain RskA PF10099.9 CDJ51335.1 - 0.22 11.8 48.5 0.029 14.7 22.9 3.6 2 1 2 4 4 4 0 Anti-sigma-K factor rskA NKAP PF15692.5 CDJ51335.1 - 0.22 12.3 0.1 0.22 12.3 0.1 3.0 3 0 0 3 3 3 0 NF-kappa-B-activating protein eIF_4EBP PF05456.11 CDJ51335.1 - 0.64 10.0 14.7 0.11 12.4 1.5 3.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) MDM10 PF12519.8 CDJ51335.1 - 9 5.0 9.1 4.7 6.0 0.9 2.1 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 RR_TM4-6 PF06459.12 CDJ51336.1 - 0.00035 20.5 19.3 0.00035 20.5 19.3 2.1 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 Hamartin PF04388.12 CDJ51336.1 - 0.0026 16.5 22.3 0.0034 16.1 22.3 1.1 1 0 0 1 1 1 1 Hamartin protein Lin-8 PF03353.15 CDJ51336.1 - 0.087 12.4 36.4 0.25 10.9 27.9 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Nha1_C PF08619.10 CDJ51336.1 - 0.15 11.3 31.0 0.2 10.9 31.0 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF3807 PF12720.7 CDJ51336.1 - 0.16 12.2 36.5 0.19 12.0 29.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) FAM60A PF15396.6 CDJ51336.1 - 0.24 11.4 20.5 0.16 11.9 15.7 2.0 2 0 0 2 2 2 0 Protein Family FAM60A CCSAP PF15748.5 CDJ51336.1 - 0.26 11.4 32.7 0.15 12.2 24.0 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF1387 PF07139.11 CDJ51336.1 - 0.41 10.3 24.0 0.084 12.6 15.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) TCP PF03634.13 CDJ51336.1 - 0.69 10.5 28.5 0.26 11.9 20.1 2.3 2 0 0 2 2 2 0 TCP family transcription factor DUF913 PF06025.12 CDJ51336.1 - 1.2 8.1 19.1 0.38 9.7 13.6 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DAG_kinase_N PF14513.6 CDJ51336.1 - 1.6 8.9 30.7 2.3 8.4 24.9 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus SLC12 PF03522.15 CDJ51336.1 - 1.8 7.5 30.1 2 7.3 25.4 2.0 2 0 0 2 2 2 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ51336.1 - 2.1 6.7 10.8 0.18 10.2 6.2 1.5 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 CDJ51336.1 - 2.2 7.0 37.5 0.68 8.6 29.7 2.1 2 0 0 2 2 2 0 Presenilin SRP-alpha_N PF04086.13 CDJ51336.1 - 3.2 7.6 29.7 2.5 8.0 22.1 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF2052 PF09747.9 CDJ51336.1 - 3.4 7.7 32.8 3.7 7.6 27.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Smg8_Smg9 PF10220.9 CDJ51336.1 - 4.1 5.6 24.0 0.12 10.7 16.9 1.8 2 0 0 2 2 2 0 Smg8_Smg9 Tyrosinase PF00264.20 CDJ51336.1 - 5.5 7.2 14.6 2.8 8.2 10.6 2.0 2 0 0 2 2 2 0 Common central domain of tyrosinase PPL5 PF18168.1 CDJ51336.1 - 6.9 5.9 18.7 1.1 8.5 13.4 2.0 2 0 0 2 2 2 0 Prim-pol family 5 ALMT PF11744.8 CDJ51336.1 - 9.6 4.9 23.8 2.8 6.7 18.6 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter SF-assemblin PF06705.11 CDJ51339.1 - 3e-14 53.0 2.5 3e-14 53.0 2.5 3.9 4 0 0 4 4 4 1 SF-assemblin/beta giardin SR-25 PF10500.9 CDJ51339.1 - 0.0013 18.4 13.8 0.0013 18.4 13.8 11.3 11 1 1 12 12 12 3 Nuclear RNA-splicing-associated protein Otopetrin PF03189.13 CDJ51339.1 - 0.83 8.4 0.0 0.83 8.4 0.0 6.1 5 2 0 5 5 5 0 Otopetrin BatD PF13584.6 CDJ51340.1 - 0.0012 17.8 0.1 0.0012 17.8 0.1 1.8 1 1 1 2 2 2 1 Oxygen tolerance DUF4131 PF13567.6 CDJ51340.1 - 0.029 14.0 0.2 0.041 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) V_ATPase_I PF01496.19 CDJ51340.1 - 0.045 11.7 0.8 0.044 11.7 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Shadoo PF14999.6 CDJ51340.1 - 0.048 13.8 5.7 0.085 13.0 5.7 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective TRAP_alpha PF03896.16 CDJ51340.1 - 0.051 12.8 0.2 0.07 12.3 0.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SR-25 PF10500.9 CDJ51340.1 - 0.49 10.0 17.6 0.36 10.4 1.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4834 PF16118.5 CDJ51340.1 - 1.2 10.2 8.7 0.36 11.8 4.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Ctr PF04145.15 CDJ51340.1 - 4.2 8.0 5.7 0.98 10.0 1.5 1.9 1 1 1 2 2 2 0 Ctr copper transporter family CDK2AP PF09806.9 CDJ51340.1 - 8.9 6.3 18.6 1.8 8.6 14.3 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein RELT PF12606.8 CDJ51341.1 - 3.3 6.8 5.1 2.8 7.0 0.4 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 SUIM_assoc PF16619.5 CDJ51342.1 - 0.043 13.9 7.4 0.043 13.9 7.4 3.9 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 BAF1_ABF1 PF04684.13 CDJ51342.1 - 0.044 12.8 3.2 0.064 12.3 3.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4834 PF16118.5 CDJ51342.1 - 0.096 13.7 7.9 4.8 8.2 4.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4813 PF16072.5 CDJ51342.1 - 0.13 11.9 13.2 0.18 11.4 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) RskA PF10099.9 CDJ51342.1 - 0.14 12.4 32.7 0.81 10.0 1.0 2.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA AUX_IAA PF02309.16 CDJ51342.1 - 0.41 10.5 3.2 0.67 9.8 3.2 1.3 1 0 0 1 1 1 0 AUX/IAA family Activator_LAG-3 PF11498.8 CDJ51342.1 - 0.59 9.0 34.3 0.13 11.2 15.1 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DFRP_C PF16543.5 CDJ51342.1 - 1.6 9.2 5.7 14 6.2 0.0 2.2 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 PulG PF11773.8 CDJ51342.1 - 3 7.7 10.4 0.53 10.2 0.7 2.3 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin DUF2489 PF10675.9 CDJ51342.1 - 3.5 7.6 20.1 4.2 7.3 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Mpp10 PF04006.12 CDJ51343.1 - 2.6e-19 69.2 13.7 3.6e-19 68.7 13.7 1.2 1 0 0 1 1 1 1 Mpp10 protein PH_9 PF15410.6 CDJ51343.1 - 0.075 13.4 2.9 0.14 12.6 2.9 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Herpes_pp85 PF04637.12 CDJ51343.1 - 0.2 10.0 6.5 1.9 6.8 0.4 2.2 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3446 PF11928.8 CDJ51343.1 - 0.24 11.7 14.2 0.12 12.6 4.0 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain CCSAP PF15748.5 CDJ51343.1 - 0.62 10.2 25.4 0.077 13.2 21.5 1.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Neur_chan_memb PF02932.16 CDJ51343.1 - 1.1 9.2 7.2 1.5 8.8 7.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mit_KHE1 PF10173.9 CDJ51343.1 - 2.6 8.1 12.1 3.4 7.7 10.4 1.9 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related SR-25 PF10500.9 CDJ51343.1 - 8 6.0 47.2 0.051 13.2 16.5 2.8 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Mpp10 PF04006.12 CDJ51344.1 - 3.2e-11 42.4 101.3 3.2e-11 42.4 101.3 3.3 1 1 1 2 2 2 1 Mpp10 protein LptF_LptG PF03739.14 CDJ51345.1 - 0.016 14.1 0.0 0.034 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG SPX PF03105.19 CDJ51345.1 - 1.3 8.9 11.6 1.6 8.5 7.7 2.2 2 0 0 2 2 2 0 SPX domain Rotamase PF00639.21 CDJ51346.1 - 1.1e-11 45.6 16.5 2.2e-10 41.3 9.6 3.2 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CDJ51346.1 - 5.2e-10 39.9 3.0 8.5e-10 39.2 1.9 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain Acylphosphatase PF00708.18 CDJ51346.1 - 0.00083 19.7 0.4 0.00083 19.7 0.4 2.9 2 1 1 3 3 3 1 Acylphosphatase EMC3_TMCO1 PF01956.16 CDJ51346.1 - 0.016 15.0 3.1 0.032 14.0 3.2 1.4 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like LMBR1 PF04791.16 CDJ51346.1 - 0.085 11.8 2.9 0.081 11.8 2.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 CDJ51346.1 - 0.18 10.4 7.7 0.23 10.0 7.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2203 PF09969.9 CDJ51346.1 - 0.34 11.6 8.5 0.9 10.3 8.5 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) PAT1 PF09770.9 CDJ51346.1 - 0.43 8.8 22.1 0.47 8.7 22.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_32 PF13654.6 CDJ51346.1 - 0.69 8.6 12.6 0.94 8.2 12.6 1.1 1 0 0 1 1 1 0 AAA domain CENP-H PF05837.12 CDJ51346.1 - 1 9.8 17.5 2.6 8.5 17.5 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) 5_nucleotid PF05761.14 CDJ51346.1 - 1 8.2 12.3 1.5 7.6 12.3 1.2 1 0 0 1 1 1 0 5' nucleotidase family Golgin_A5 PF09787.9 CDJ51346.1 - 3.1 7.2 28.5 0.17 11.3 23.1 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 YbgS PF13985.6 CDJ51346.1 - 3.6 7.9 11.4 7.5 6.9 11.4 1.5 1 0 0 1 1 1 0 YbgS-like protein CemA PF03040.14 CDJ51346.1 - 4.7 7.1 6.1 6.3 6.7 6.1 1.2 1 0 0 1 1 1 0 CemA family Ribosomal_60s PF00428.19 CDJ51346.1 - 6.8 7.4 18.2 1.3 9.6 14.3 1.9 2 0 0 2 2 1 0 60s Acidic ribosomal protein TMPIT PF07851.13 CDJ51346.1 - 7.2 5.8 16.3 14 4.8 16.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein Tox-ODYAM1 PF15642.6 CDJ51346.1 - 8 5.3 12.8 12 4.8 12.8 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus IBN_N PF03810.19 CDJ51347.1 - 5.6e-14 51.8 1.8 5.6e-14 51.8 1.8 5.1 3 1 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 CDJ51347.1 - 2.8e-07 29.7 17.2 4.5e-07 29.0 0.0 3.7 3 1 1 4 4 4 2 Cse1 RskA PF10099.9 CDJ51347.1 - 8.1e-05 23.0 4.0 8.1e-05 23.0 4.0 4.9 1 1 3 4 4 4 2 Anti-sigma-K factor rskA Auxin_canalis PF05703.11 CDJ51347.1 - 0.001 19.1 5.1 0.001 19.1 5.1 2.2 3 0 0 3 3 3 1 Auxin canalisation SR-25 PF10500.9 CDJ51347.1 - 0.0084 15.7 4.1 0.037 13.6 0.6 2.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CSN5_C PF18323.1 CDJ51347.1 - 0.022 15.7 3.4 0.022 15.7 3.4 4.1 4 1 0 4 4 4 0 Cop9 signalosome subunit 5 C-terminal domain BCD PF15461.6 CDJ51347.1 - 0.045 13.3 0.2 0.092 12.2 0.2 1.5 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Ribosomal_60s PF00428.19 CDJ51347.1 - 0.57 10.8 9.7 33 5.2 12.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein INO80_Ies4 PF08193.11 CDJ51347.1 - 7.2 6.5 9.6 3.9 7.4 0.6 2.4 2 0 0 2 2 2 0 INO80 complex subunit Ies4 DDRGK PF09756.9 CDJ51348.1 - 0.34 10.5 17.1 0.33 10.5 17.1 1.1 1 0 0 1 1 1 0 DDRGK domain PI3K_1B_p101 PF10486.9 CDJ51348.1 - 2.8 5.6 26.5 3.1 5.4 26.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1645 PF07816.11 CDJ51348.1 - 4.4 7.9 32.3 5.2 7.6 32.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) NARP1 PF12569.8 CDJ51348.1 - 6.5 5.5 14.6 6.3 5.6 14.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NST1 PF13945.6 CDJ51348.1 - 8.6 6.4 37.7 9.3 6.3 37.7 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator Macoilin PF09726.9 CDJ51348.1 - 8.7 4.8 37.2 9.1 4.7 37.2 1.0 1 0 0 1 1 1 0 Macoilin family CAS_CSE1 PF03378.15 CDJ51349.1 - 1.5e-17 63.3 11.2 4e-17 61.9 11.2 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 CDJ51349.1 - 8e-14 51.2 1.5 2.2e-13 49.8 0.0 2.4 3 0 0 3 3 3 1 Cse1 Spt20 PF12090.8 CDJ51349.1 - 0.0022 17.6 11.4 0.0022 17.6 11.4 6.0 6 0 0 6 6 6 3 Spt20 family DUF3138 PF11336.8 CDJ51350.1 - 3 6.3 11.7 1 7.9 9.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) OCC1 PF15506.6 CDJ51351.1 - 0.057 13.5 1.1 0.057 13.5 1.1 3.4 4 0 0 4 4 4 0 OCC1 family Aminotran_1_2 PF00155.21 CDJ51351.1 - 1 8.5 6.3 0.18 10.9 0.3 2.1 2 0 0 2 2 2 0 Aminotransferase class I and II RskA PF10099.9 CDJ51351.1 - 1.4 9.2 42.1 0.67 10.2 14.9 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF4553 PF15090.6 CDJ51351.1 - 3.6 6.4 18.6 4.6 6.1 18.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) DDRGK PF09756.9 CDJ51352.1 - 9.9 5.7 27.0 9.9 5.7 27.0 1.1 1 0 0 1 1 1 0 DDRGK domain TERB2 PF15101.6 CDJ51353.1 - 0.11 12.5 41.5 0.27 11.3 20.2 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 EIF4E-T PF10477.9 CDJ51353.1 - 0.61 8.9 40.2 0.71 8.6 40.2 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E SR-25 PF10500.9 CDJ51353.1 - 0.72 9.4 39.7 0.61 9.7 15.2 2.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein SelP_N PF04592.14 CDJ51353.1 - 1 8.7 32.3 0.94 8.8 13.6 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DcuA_DcuB PF03605.14 CDJ51353.1 - 1.3 7.8 24.7 0.37 9.6 12.8 2.0 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter AIF_C PF14721.6 CDJ51353.1 - 1.4 9.3 29.6 2.1 8.7 10.7 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Coilin_N PF15862.5 CDJ51353.1 - 2.1 8.2 41.8 1.3 8.8 15.0 2.4 2 0 0 2 2 2 0 Coilin N-terminus CD20 PF04103.15 CDJ51353.1 - 2.1 8.4 10.2 0.36 10.9 0.1 2.2 1 1 1 2 2 2 0 CD20-like family Rxt3 PF08642.10 CDJ51353.1 - 4.3 8.1 19.0 8.2 7.2 6.4 2.5 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF1764 PF08576.10 CDJ51353.1 - 6.6 7.7 33.5 12 6.8 15.5 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF3408 PF11888.8 CDJ51353.1 - 7.9 6.6 34.6 2.6 8.2 14.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Connexin PF00029.19 CDJ51353.1 - 8.4 6.1 30.4 2.2 8.0 12.2 2.1 2 0 0 2 2 2 0 Connexin RR_TM4-6 PF06459.12 CDJ51354.1 - 0.11 12.3 17.1 0.71 9.6 1.2 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Dmrt1 PF12374.8 CDJ51354.1 - 0.75 10.3 9.7 0.86 10.1 0.9 2.4 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Orf78 PF06024.12 CDJ51354.1 - 3.1 8.1 13.9 0.34 11.2 3.5 3.0 4 0 0 4 4 4 0 Orf78 (ac78) AIF_C PF14721.6 CDJ51354.1 - 6.2 7.2 18.3 0.32 11.3 5.5 3.2 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Med8 PF10232.9 CDJ51355.1 - 0.0042 16.7 6.2 0.0064 16.1 6.2 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF2362 PF10154.9 CDJ51355.1 - 0.039 12.9 6.7 0.046 12.7 6.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) HflK_N PF12221.8 CDJ51355.1 - 0.041 13.9 2.5 0.24 11.4 0.6 2.2 2 0 0 2 2 2 0 Bacterial membrane protein N terminal DUF3881 PF12997.7 CDJ51355.1 - 0.055 12.7 4.0 0.077 12.2 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) DUF2099 PF09872.9 CDJ51355.1 - 0.1 11.8 5.8 0.19 10.9 5.8 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) DUF4330 PF14221.6 CDJ51355.1 - 0.13 12.4 0.5 0.13 12.4 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4330) RusA PF05866.11 CDJ51355.1 - 0.16 12.5 2.6 0.3 11.7 2.6 1.5 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA TFIIA PF03153.13 CDJ51355.1 - 0.17 11.8 27.6 0.21 11.5 27.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Oxidored_q6 PF01058.22 CDJ51355.1 - 0.42 10.5 3.5 0.3 10.9 0.8 1.9 1 1 1 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Sigma70_ECF PF07638.11 CDJ51355.1 - 0.51 10.2 9.6 0.19 11.6 7.0 1.6 2 0 0 2 2 2 0 ECF sigma factor DUF3997 PF13162.6 CDJ51355.1 - 0.69 10.2 7.5 0.29 11.5 4.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3997) TPR_7 PF13176.6 CDJ51355.1 - 3.2 8.0 10.0 14 5.9 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RAB3GAP2_N PF14655.6 CDJ51357.1 - 0.00015 21.2 4.7 0.00015 21.2 4.7 8.7 5 3 2 7 7 7 1 Rab3 GTPase-activating protein regulatory subunit N-terminus V_ATPase_I PF01496.19 CDJ51358.1 - 0.021 12.8 2.5 0.028 12.4 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HABP4_PAI-RBP1 PF04774.15 CDJ51358.1 - 0.024 15.5 4.8 0.024 15.5 4.8 2.0 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family SAPS PF04499.15 CDJ51358.1 - 0.034 13.0 0.6 0.036 12.8 0.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HNOBA PF07701.14 CDJ51358.1 - 0.048 13.1 0.5 0.048 13.1 0.5 1.8 2 0 0 2 2 2 0 Heme NO binding associated SpoIIP PF07454.11 CDJ51358.1 - 0.13 11.7 6.3 0.042 13.3 1.4 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2828 PF11443.8 CDJ51358.1 - 0.14 10.2 2.8 0.19 9.8 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) AUX_IAA PF02309.16 CDJ51358.1 - 0.45 10.3 4.0 0.7 9.7 4.0 1.4 1 1 0 1 1 1 0 AUX/IAA family DUF3306 PF11748.8 CDJ51358.1 - 0.47 11.3 9.9 0.24 12.3 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Suf PF05843.14 CDJ51358.1 - 0.55 10.2 15.2 0.28 11.1 7.0 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) EPL1 PF10513.9 CDJ51358.1 - 0.62 10.4 10.6 2.1 8.7 5.9 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Peroxin-3 PF04882.12 CDJ51358.1 - 1.2 8.1 8.9 1.3 7.9 8.9 1.2 1 0 0 1 1 1 0 Peroxin-3 RR_TM4-6 PF06459.12 CDJ51358.1 - 1.9 8.3 12.5 1.5 8.6 9.1 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TCP PF03634.13 CDJ51358.1 - 2.6 8.6 14.4 6.6 7.3 0.6 2.1 2 0 0 2 2 2 0 TCP family transcription factor EIIBC-GUT_N PF03612.14 CDJ51358.1 - 4 7.1 9.7 33 4.1 8.4 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF908 PF06012.12 CDJ51358.1 - 4.5 6.6 11.0 6 6.2 10.8 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF3391 PF11871.8 CDJ51358.1 - 4.8 7.7 16.0 6.9 7.2 10.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) SprA-related PF12118.8 CDJ51358.1 - 5.1 6.1 27.1 5.1 6.1 19.7 2.2 2 0 0 2 2 2 0 SprA-related family Roughex PF06020.11 CDJ51358.1 - 5.5 6.0 25.2 0.087 11.9 12.4 2.1 2 0 0 2 2 2 0 Drosophila roughex protein Band_3_cyto PF07565.13 CDJ51358.1 - 5.7 6.7 9.8 4.5 7.0 4.9 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Connexin PF00029.19 CDJ51358.1 - 6.4 6.5 6.0 13 5.4 4.6 1.8 2 0 0 2 2 2 0 Connexin SMN PF06003.12 CDJ51358.1 - 6.9 5.8 13.8 0.24 10.6 4.6 2.1 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) FAM176 PF14851.6 CDJ51358.1 - 8.3 6.1 8.1 7.6 6.2 5.5 1.9 2 0 0 2 2 2 0 FAM176 family DUF5521 PF17659.1 CDJ51358.1 - 8.8 4.0 6.5 12 3.6 6.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) SLATT_1 PF18181.1 CDJ51359.1 - 0.092 12.7 8.5 0.11 12.4 8.5 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF1631 PF07793.11 CDJ51359.1 - 8 4.8 13.8 8.4 4.7 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Methyltransf_16 PF10294.9 CDJ51360.1 - 2.6e-06 27.3 0.1 9.6e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Lysine methyltransferase Trypan_PARP PF05887.11 CDJ51361.1 - 0.0018 18.2 6.4 0.0018 18.2 6.4 2.4 2 1 1 3 3 3 1 Procyclic acidic repetitive protein (PARP) SUIM_assoc PF16619.5 CDJ51361.1 - 0.0063 16.6 3.9 0.0063 16.6 3.9 7.9 5 1 2 7 7 7 2 Unstructured region C-term to UIM in Ataxin3 Draxin PF15550.6 CDJ51361.1 - 1.5 8.6 21.3 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Draxin SUIM_assoc PF16619.5 CDJ51363.1 - 0.00022 21.2 14.4 0.0057 16.7 0.1 3.8 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 zf-B_box PF00643.24 CDJ51363.1 - 0.00082 19.5 6.2 0.0015 18.6 6.2 1.4 1 0 0 1 1 1 1 B-box zinc finger TFIIA PF03153.13 CDJ51363.1 - 0.0086 16.1 9.4 0.0086 16.1 9.4 2.0 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit DUF3357 PF11837.8 CDJ51363.1 - 2.4 8.7 11.2 2.7 8.5 7.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) MAT1 PF06391.13 CDJ51364.1 - 1.9 8.2 26.9 1.1 9.0 17.8 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Hydin_ADK PF17213.3 CDJ51364.1 - 4.1 7.6 17.6 30 4.8 0.1 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF572 PF04502.13 CDJ51364.1 - 9.7 5.7 15.5 22 4.6 10.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Spt20 PF12090.8 CDJ51365.1 - 0.0033 17.1 9.7 0.0033 17.1 9.7 4.6 4 0 0 4 4 4 3 Spt20 family Pan3_PK PF18101.1 CDJ51366.1 - 7e-26 90.8 1.8 2.9e-20 72.7 0.0 3.4 3 0 0 3 3 3 2 Pan3 Pseudokinase domain SPX PF03105.19 CDJ51366.1 - 0.00059 19.9 7.5 0.00059 19.9 7.5 6.3 3 1 0 3 3 3 1 SPX domain RskA PF10099.9 CDJ51366.1 - 0.0071 16.7 13.1 0.0071 16.7 13.1 12.8 3 2 6 9 9 9 2 Anti-sigma-K factor rskA DUF913 PF06025.12 CDJ51368.1 - 0.0026 16.8 5.4 0.0032 16.5 5.4 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) CobT PF06213.12 CDJ51368.1 - 0.053 12.9 28.3 0.069 12.5 28.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4746 PF15928.5 CDJ51368.1 - 0.056 12.9 14.2 0.066 12.6 14.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2052 PF09747.9 CDJ51368.1 - 0.07 13.2 18.8 0.08 13.1 18.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF1180 PF06679.12 CDJ51368.1 - 0.094 13.1 4.3 0.13 12.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Kei1 PF08552.11 CDJ51368.1 - 0.11 12.4 7.9 0.17 11.8 7.9 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Presenilin PF01080.17 CDJ51368.1 - 0.11 11.2 24.7 0.12 11.1 24.7 1.0 1 0 0 1 1 1 0 Presenilin XRN_M PF17846.1 CDJ51368.1 - 0.11 11.4 11.9 0.13 11.2 11.9 1.0 1 0 0 1 1 1 0 Xrn1 helical domain NPR3 PF03666.13 CDJ51368.1 - 0.12 11.1 18.2 0.14 10.9 18.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Gti1_Pac2 PF09729.9 CDJ51368.1 - 0.2 11.7 15.1 0.24 11.5 15.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2347 PF09804.9 CDJ51368.1 - 0.2 11.2 6.5 0.27 10.8 6.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF2828 PF11443.8 CDJ51368.1 - 0.38 8.8 17.0 0.4 8.7 17.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PTPRCAP PF15713.5 CDJ51368.1 - 0.39 11.0 23.0 0.51 10.6 23.0 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Otopetrin PF03189.13 CDJ51368.1 - 0.39 9.5 10.6 0.48 9.2 10.6 1.1 1 0 0 1 1 1 0 Otopetrin CLN3 PF02487.17 CDJ51368.1 - 0.41 9.6 13.3 0.52 9.3 13.3 1.1 1 0 0 1 1 1 0 CLN3 protein Hid1 PF12722.7 CDJ51368.1 - 0.44 8.6 18.9 0.49 8.5 18.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCDC53 PF10152.9 CDJ51368.1 - 0.46 10.9 19.6 0.59 10.5 19.6 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CDC45 PF02724.14 CDJ51368.1 - 0.47 8.7 17.4 0.56 8.4 17.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.6 CDJ51368.1 - 0.5 8.7 6.3 0.6 8.5 6.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BORG_CEP PF14957.6 CDJ51368.1 - 0.5 11.5 12.5 0.61 11.3 12.5 1.1 1 0 0 1 1 1 0 Cdc42 effector CSG2 PF16965.5 CDJ51368.1 - 0.54 9.2 6.9 0.67 8.8 6.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator FAM60A PF15396.6 CDJ51368.1 - 0.56 10.2 13.3 0.68 9.9 13.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Serinc PF03348.15 CDJ51368.1 - 0.59 9.0 9.0 0.77 8.6 9.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.16 CDJ51368.1 - 0.62 10.1 18.1 0.74 9.8 18.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4638 PF15472.6 CDJ51368.1 - 0.62 9.7 19.9 0.75 9.5 19.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Folliculin PF11704.8 CDJ51368.1 - 0.86 9.5 15.0 1.3 8.8 15.0 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport ALMT PF11744.8 CDJ51368.1 - 0.94 8.2 14.8 1.1 8.1 14.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 CDJ51368.1 - 1 9.3 52.6 1.2 9.0 52.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ51368.1 - 1.1 8.2 20.9 1.3 7.9 20.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Mem_trans PF03547.18 CDJ51368.1 - 1.2 7.5 6.6 1.5 7.2 6.6 1.1 1 0 0 1 1 1 0 Membrane transport protein AUX_IAA PF02309.16 CDJ51368.1 - 1.2 8.9 12.9 1.3 8.8 12.9 1.1 1 0 0 1 1 1 0 AUX/IAA family V_ATPase_I PF01496.19 CDJ51368.1 - 1.2 6.9 20.9 1.4 6.8 20.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paf1 PF03985.13 CDJ51368.1 - 1.5 7.7 24.6 2 7.4 24.6 1.1 1 0 0 1 1 1 0 Paf1 VIR_N PF15912.5 CDJ51368.1 - 1.5 8.3 12.1 1.7 8.2 12.1 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal RR_TM4-6 PF06459.12 CDJ51368.1 - 1.8 8.4 24.6 2.2 8.1 24.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 CDJ51368.1 - 2.2 7.4 12.5 2.7 7.1 12.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CCSAP PF15748.5 CDJ51368.1 - 2.2 8.4 24.8 2.7 8.1 24.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF2370 PF10176.9 CDJ51368.1 - 2.5 7.7 9.9 3.1 7.4 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) CBP_BcsG PF11658.8 CDJ51368.1 - 2.8 6.3 15.5 3.8 5.8 15.5 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF908 PF06012.12 CDJ51368.1 - 2.8 7.3 17.1 3.4 7.0 17.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Miga PF10265.9 CDJ51368.1 - 3.1 6.7 11.9 3.6 6.4 11.9 1.1 1 0 0 1 1 1 0 Mitoguardin PAT1 PF09770.9 CDJ51368.1 - 3.3 5.8 36.4 3.6 5.8 36.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4228 PF14009.6 CDJ51368.1 - 3.8 7.9 12.2 4.6 7.6 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF2464 PF10240.9 CDJ51368.1 - 4.2 6.9 11.4 5.1 6.6 11.4 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 Rrn6 PF10214.9 CDJ51368.1 - 4.2 5.7 26.6 5 5.5 26.6 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor GPCR_chapero_1 PF11904.8 CDJ51368.1 - 5.9 6.2 15.5 7.3 5.9 15.5 1.0 1 0 0 1 1 1 0 GPCR-chaperone HCO3_cotransp PF00955.21 CDJ51368.1 - 7.3 5.3 6.8 8.2 5.1 6.8 1.0 1 0 0 1 1 1 0 HCO3- transporter family DUF3381 PF11861.8 CDJ51368.1 - 7.4 6.3 26.8 11 5.7 26.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Membralin PF09746.9 CDJ51368.1 - 9.6 5.1 12.9 11 4.9 12.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein Lin-8 PF03353.15 CDJ51370.1 - 0.00033 20.3 15.3 0.00033 20.3 15.3 6.0 5 1 0 6 6 6 2 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 CDJ51370.1 - 0.002 17.0 28.2 0.002 17.0 28.2 5.9 4 1 0 4 4 4 2 Presenilin DcuA_DcuB PF03605.14 CDJ51370.1 - 0.011 14.6 0.3 0.011 14.6 0.3 4.8 4 1 1 5 5 5 0 Anaerobic c4-dicarboxylate membrane transporter RskA PF10099.9 CDJ51372.1 - 8e-05 23.0 7.7 8.9e-05 22.9 7.7 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Sporozoite_P67 PF05642.11 CDJ51372.1 - 0.011 13.9 0.2 0.011 13.8 0.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Bac_luciferase PF00296.20 CDJ51372.1 - 0.015 14.8 5.8 0.018 14.5 5.8 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF4820 PF16091.5 CDJ51372.1 - 0.039 13.3 3.3 0.042 13.2 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Na_K-ATPase PF00287.18 CDJ51372.1 - 0.047 12.8 4.6 0.052 12.7 4.6 1.0 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain eIF-3_zeta PF05091.12 CDJ51372.1 - 0.097 11.6 11.7 0.098 11.6 11.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ51372.1 - 0.1 12.7 7.8 0.11 12.5 7.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 V_ATPase_I PF01496.19 CDJ51372.1 - 0.13 10.2 3.2 0.13 10.1 3.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ51372.1 - 0.18 11.8 21.1 0.19 11.7 21.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ51372.1 - 0.18 11.2 4.3 0.19 11.1 4.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CDJ51372.1 - 0.2 10.4 6.3 0.2 10.4 6.3 1.1 1 0 0 1 1 1 0 Presenilin API5 PF05918.11 CDJ51372.1 - 0.33 9.7 9.9 0.31 9.8 9.9 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Spt20 PF12090.8 CDJ51372.1 - 0.44 10.1 28.1 0.53 9.9 28.1 1.1 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 CDJ51372.1 - 1 9.4 4.1 1 9.4 4.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BRF1 PF07741.13 CDJ51372.1 - 1.3 9.4 8.5 2.1 8.7 8.5 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Usp PF00582.26 CDJ51372.1 - 1.8 9.1 4.5 3.2 8.2 4.5 1.5 1 1 0 1 1 1 0 Universal stress protein family Band_3_cyto PF07565.13 CDJ51372.1 - 2 8.2 5.5 2.2 8.0 5.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Suf PF05843.14 CDJ51372.1 - 2.6 7.9 11.1 2.7 7.9 11.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0560 PF10577.9 CDJ51372.1 - 3 6.2 12.3 3 6.2 12.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4834 PF16118.5 CDJ51372.1 - 3.4 8.7 12.9 4.5 8.3 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2897 PF11446.8 CDJ51372.1 - 6.4 6.7 5.5 12 5.8 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Peptidase_C97 PF05903.14 CDJ51373.1 - 0.003 17.4 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Sporozoite_P67 PF05642.11 CDJ51373.1 - 0.0046 15.1 0.2 0.0046 15.1 0.2 1.9 2 1 0 2 2 2 1 Sporozoite P67 surface antigen Cauli_DNA-bind PF03310.13 CDJ51373.1 - 1 9.4 0.0 1 9.4 0.0 3.0 4 0 0 4 4 4 0 Caulimovirus DNA-binding protein Med15 PF09606.10 CDJ51373.1 - 1.2 7.7 84.0 0.25 10.0 59.8 2.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.16 CDJ51373.1 - 3.4 7.7 22.6 0.43 10.6 1.0 3.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ51374.1 - 0.00032 19.6 23.9 0.00043 19.2 23.9 1.1 1 0 0 1 1 1 1 Presenilin Peptidase_S64 PF08192.11 CDJ51374.1 - 0.0019 16.8 19.6 0.0024 16.4 19.6 1.1 1 0 0 1 1 1 1 Peptidase family S64 SID-1_RNA_chan PF13965.6 CDJ51374.1 - 0.0096 14.4 3.6 0.012 14.1 3.6 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Zip PF02535.22 CDJ51374.1 - 0.014 14.7 13.4 0.023 13.9 13.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2052 PF09747.9 CDJ51374.1 - 0.014 15.5 23.6 0.021 14.9 23.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pkinase_fungal PF17667.1 CDJ51374.1 - 0.017 14.0 7.4 0.018 13.8 7.4 1.1 1 0 0 1 1 1 0 Fungal protein kinase Endostatin PF06482.11 CDJ51374.1 - 0.018 14.5 17.0 0.024 14.1 17.0 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Exonuc_VII_L PF02601.15 CDJ51374.1 - 0.02 14.5 19.0 0.028 14.0 19.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GREB1 PF15782.5 CDJ51374.1 - 0.02 12.0 21.5 0.025 11.8 21.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ51374.1 - 0.022 13.1 39.1 0.028 12.7 39.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Slu7 PF11708.8 CDJ51374.1 - 0.033 13.9 22.0 0.051 13.3 22.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Miga PF10265.9 CDJ51374.1 - 0.047 12.7 10.3 0.058 12.4 10.3 1.1 1 0 0 1 1 1 0 Mitoguardin V_ATPase_I PF01496.19 CDJ51374.1 - 0.055 11.4 19.6 0.072 11.0 19.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1387 PF07139.11 CDJ51374.1 - 0.068 12.9 20.1 0.096 12.4 20.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Radical_SAM_N PF08497.10 CDJ51374.1 - 0.11 11.6 7.1 0.14 11.4 7.1 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal Sporozoite_P67 PF05642.11 CDJ51374.1 - 0.14 10.2 4.8 0.13 10.3 4.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4045 PF13254.6 CDJ51374.1 - 0.16 11.6 23.2 0.22 11.1 23.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CAC1F_C PF16885.5 CDJ51374.1 - 0.19 11.4 17.9 0.25 10.9 17.9 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Asp-B-Hydro_N PF05279.11 CDJ51374.1 - 0.19 11.8 22.5 0.26 11.3 22.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CobT PF06213.12 CDJ51374.1 - 0.2 11.0 34.5 0.43 9.9 34.5 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Dapper PF15268.6 CDJ51374.1 - 0.27 10.1 27.4 0.34 9.7 27.4 1.1 1 0 0 1 1 1 0 Dapper Paf1 PF03985.13 CDJ51374.1 - 0.29 10.1 29.9 0.4 9.6 29.9 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 CDJ51374.1 - 0.38 9.0 25.3 0.51 8.6 25.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CCSAP PF15748.5 CDJ51374.1 - 0.41 10.8 30.2 0.6 10.2 30.2 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Mem_trans PF03547.18 CDJ51374.1 - 0.66 8.3 2.1 0.8 8.0 2.1 1.2 1 0 0 1 1 1 0 Membrane transport protein NPR3 PF03666.13 CDJ51374.1 - 0.81 8.4 24.5 1 8.1 24.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 EPL1 PF10513.9 CDJ51374.1 - 1 9.7 30.2 14 6.0 30.2 2.2 1 1 0 1 1 1 0 Enhancer of polycomb-like Hid1 PF12722.7 CDJ51374.1 - 1.4 6.9 25.5 2 6.5 25.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3295 PF11702.8 CDJ51374.1 - 1.4 8.1 25.1 1.9 7.7 25.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF4050 PF13259.6 CDJ51374.1 - 2.1 8.7 22.6 3.3 8.0 22.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Hydin_ADK PF17213.3 CDJ51374.1 - 2.6 8.3 18.9 5 7.4 18.9 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Tim54 PF11711.8 CDJ51374.1 - 2.7 6.7 21.1 5.1 5.8 21.1 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Velvet PF11754.8 CDJ51374.1 - 3.1 7.6 22.4 4.7 7.1 22.4 1.3 1 0 0 1 1 1 0 Velvet factor SLC12 PF03522.15 CDJ51374.1 - 4.1 6.3 29.0 5.4 5.9 29.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4746 PF15928.5 CDJ51374.1 - 4.7 6.6 21.7 8.7 5.7 21.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) LMBR1 PF04791.16 CDJ51374.1 - 4.7 6.0 10.0 5.6 5.8 10.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.16 CDJ51374.1 - 5.5 7.0 24.3 7.7 6.5 24.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SRP-alpha_N PF04086.13 CDJ51374.1 - 8.1 6.3 28.6 12 5.7 28.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PIG-S PF10510.9 CDJ51374.1 - 8.6 5.1 20.7 12 4.6 20.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Band_3_cyto PF07565.13 CDJ51374.1 - 8.7 6.1 29.5 15 5.3 29.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SAPS PF04499.15 CDJ51374.1 - 9.3 4.9 21.5 12 4.6 21.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_11 PF13086.6 CDJ51374.1 - 9.8 5.9 26.1 15 5.3 26.1 1.2 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.9 CDJ51375.1 - 0.0087 14.7 22.5 0.01 14.4 22.5 1.1 1 0 0 1 1 1 1 Macoilin family PAP1 PF08601.10 CDJ51375.1 - 0.93 9.1 33.4 1.1 8.8 33.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF778 PF05608.12 CDJ51375.1 - 6 7.2 18.9 13 6.1 18.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF778) SRP-alpha_N PF04086.13 CDJ51375.1 - 8.3 6.2 22.2 11 5.9 22.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Peptidase_S64 PF08192.11 CDJ51375.1 - 8.4 4.7 26.7 12 4.2 26.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF572 PF04502.13 CDJ51375.1 - 8.8 5.8 21.1 12 5.4 21.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4666 PF15697.5 CDJ51376.1 - 0.14 12.9 6.5 0.34 11.6 6.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4666) SUIM_assoc PF16619.5 CDJ51376.1 - 0.19 11.8 0.2 0.19 11.8 0.2 3.0 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 CDJ51376.1 - 1.4 7.6 3.2 1.6 7.4 3.2 1.3 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ51376.1 - 7.3 5.4 19.5 0.13 11.2 8.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF3626 PF12294.8 CDJ51377.1 - 1.2e-08 34.4 0.0 1.1e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3626) TPR_14 PF13428.6 CDJ51377.1 - 0.16 12.9 0.6 0.42 11.6 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SET PF00856.28 CDJ51378.1 - 0.0026 18.1 0.1 0.0066 16.9 0.1 1.7 1 0 0 1 1 1 1 SET domain Tom22 PF04281.13 CDJ51378.1 - 0.14 11.9 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Prefoldin PF02996.17 CDJ51379.1 - 1.8e-22 79.5 1.0 2.1e-22 79.3 1.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 CDJ51379.1 - 0.013 15.4 1.8 0.23 11.4 0.1 2.3 2 1 0 2 2 2 0 Prefoldin subunit DUF1627 PF07789.12 CDJ51379.1 - 0.02 14.6 0.3 0.5 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1627) Cyc-maltodext_N PF09087.11 CDJ51379.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Cyclomaltodextrinase, N-terminal Terminase_2 PF03592.16 CDJ51379.1 - 0.31 11.5 2.7 14 6.1 0.6 2.1 2 0 0 2 2 2 0 Terminase small subunit PDEase_I PF00233.19 CDJ51380.1 - 1.2e-61 208.5 0.4 2.2e-61 207.6 0.4 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GED PF02212.18 CDJ51380.1 - 0.13 12.4 0.3 0.29 11.3 0.3 1.5 1 0 0 1 1 1 0 Dynamin GTPase effector domain COX2-transmemb PF09125.10 CDJ51380.1 - 0.16 11.8 0.4 0.51 10.2 0.4 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Macoilin PF09726.9 CDJ51381.1 - 1.7 7.1 15.2 3.3 6.1 15.2 1.4 1 0 0 1 1 1 0 Macoilin family Clat_adaptor_s PF01217.20 CDJ51382.1 - 3.8e-30 104.7 0.2 3.8e-30 104.7 0.2 1.4 2 0 0 2 2 2 1 Clathrin adaptor complex small chain FTZ PF03867.14 CDJ51382.1 - 0.015 14.9 0.5 0.02 14.4 0.5 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region RskA PF10099.9 CDJ51382.1 - 0.19 12.0 0.7 0.27 11.5 0.7 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ51383.1 - 0.0086 16.1 2.4 0.0086 16.1 2.4 14.7 4 2 6 10 10 10 2 Unstructured region C-term to UIM in Ataxin3 Rav1p_C PF12234.8 CDJ51385.1 - 1.8e-18 66.4 1.8 3.3e-16 58.9 1.9 6.8 8 0 0 8 8 8 4 RAVE protein 1 C terminal DUF2722 PF10846.8 CDJ51385.1 - 0.0013 17.8 1.6 0.0013 17.8 1.6 26.0 24 3 3 27 27 27 8 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ51385.1 - 0.0061 16.9 0.3 0.0061 16.9 0.3 42.0 16 11 20 38 38 38 8 Anti-sigma-K factor rskA Auxin_inducible PF02519.14 CDJ51385.1 - 0.075 13.2 1.6 23 5.2 0.1 5.0 3 0 0 3 3 3 0 Auxin responsive protein SPG48 PF14764.6 CDJ51387.1 - 0.05 14.1 1.2 6.6 7.2 0.0 2.8 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking Surface_antigen PF11054.8 CDJ51388.1 - 2.4e-38 132.2 3.9 1.4e-37 129.7 3.9 1.8 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51389.1 - 1.5e-40 139.5 6.2 1e-39 136.7 6.2 1.8 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51390.1 - 3.6e-38 131.6 3.3 1.9e-37 129.3 3.3 1.8 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51391.1 - 1.9e-40 139.1 3.5 6e-40 137.4 3.5 1.6 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51392.1 - 0.015 15.0 0.2 0.024 14.3 0.2 1.3 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51393.1 - 2.3e-37 129.0 1.8 5.8e-36 124.4 0.1 2.4 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51394.1 - 7.1e-36 124.1 0.8 1.4e-35 123.1 0.8 1.4 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen DUF3446 PF11928.8 CDJ51394.1 - 0.06 13.7 0.1 0.06 13.7 0.1 2.0 2 1 0 2 2 2 0 Early growth response N-terminal domain Surface_antigen PF11054.8 CDJ51395.1 - 6.3e-26 91.5 0.4 8.4e-26 91.1 0.4 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51396.1 - 1.3e-36 126.5 1.0 2.1e-36 125.9 1.0 1.3 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51397.1 - 1.1e-36 126.8 0.1 2.9e-36 125.4 0.1 1.6 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51398.1 - 9.3e-37 127.0 1.2 2.3e-36 125.7 1.2 1.6 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51399.1 - 2.4e-22 79.8 0.8 3.3e-21 76.1 0.2 2.0 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51400.1 - 5.9e-36 124.4 6.7 8.3e-36 123.9 6.7 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51401.1 - 4.4e-26 92.0 0.9 3.6e-25 89.1 0.5 1.9 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51402.1 - 1.8e-40 139.2 5.9 2.2e-40 138.9 5.9 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF4886 PF16227.5 CDJ51402.1 - 0.019 14.1 0.3 0.035 13.3 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4886) Surface_antigen PF11054.8 CDJ51403.1 - 1.1e-27 97.3 5.5 1.3e-27 97.1 5.5 1.3 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51404.1 - 1e-39 136.7 4.7 1.4e-39 136.3 4.7 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF4886 PF16227.5 CDJ51404.1 - 0.011 14.9 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) Surface_antigen PF11054.8 CDJ51405.1 - 1.6e-36 126.2 4.6 2.1e-36 125.9 4.6 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen GRP PF07172.11 CDJ51405.1 - 0.0043 17.7 0.1 0.0082 16.8 0.1 1.4 1 0 0 1 1 1 1 Glycine rich protein family Surface_antigen PF11054.8 CDJ51406.1 - 1.3e-38 133.1 6.4 1.5e-38 132.9 6.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51407.1 - 7.6e-15 55.3 2.9 4.7e-13 49.4 0.8 2.1 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ51408.1 - 8.4e-40 137.0 1.5 1.1e-39 136.6 1.5 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DAG1 PF05454.11 CDJ51408.1 - 0.13 11.6 0.1 0.37 10.1 0.0 1.6 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Surface_antigen PF11054.8 CDJ51409.1 - 1.2e-121 404.9 24.7 2e-42 145.5 2.6 3.1 3 0 0 3 3 3 3 Sporozoite TA4 surface antigen OmdA PF13376.6 CDJ51409.1 - 2.4e-06 27.5 1.2 0.6 10.2 0.0 3.4 3 0 0 3 3 3 3 Bacteriocin-protection, YdeI or OmpD-Associated Pur_ac_phosph_N PF16656.5 CDJ51409.1 - 1.3e-05 25.7 1.6 2.5 8.7 0.0 3.6 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain DUF237 PF03072.14 CDJ51409.1 - 0.00043 20.3 0.1 2.5 8.1 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF237) DUF1614 PF07758.11 CDJ51409.1 - 0.002 18.2 0.2 4.4 7.3 0.0 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF1614) DUF4222 PF13973.6 CDJ51409.1 - 0.0028 17.2 0.3 16 5.2 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4222) PADR1 PF08063.12 CDJ51409.1 - 0.018 14.8 2.8 27 4.7 0.1 3.5 3 0 0 3 3 3 0 PADR1 (NUC008) domain DUF1612 PF07756.12 CDJ51409.1 - 0.049 13.9 0.0 59 3.9 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1612) rve PF00665.26 CDJ51409.1 - 0.08 13.1 0.0 97 3.2 0.0 3.5 3 0 0 3 3 3 0 Integrase core domain Integrase_DNA PF02920.15 CDJ51409.1 - 1.3 8.7 2.7 55 3.6 0.1 3.0 3 0 0 3 3 3 0 DNA binding domain of tn916 integrase TILa PF12714.7 CDJ51409.1 - 9 6.3 8.3 17 5.5 0.1 4.0 4 0 0 4 4 4 0 TILa domain Surface_antigen PF11054.8 CDJ51410.1 - 6.8e-34 117.6 2.6 8.6e-34 117.3 2.6 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen OmdA PF13376.6 CDJ51410.1 - 0.066 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Asp_protease PF09668.10 CDJ51411.1 - 3.6e-49 165.7 0.0 5.4e-49 165.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ51411.1 - 4.2e-19 68.9 0.0 8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ51411.1 - 2.4e-08 34.5 0.0 4.6e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 CDJ51411.1 - 2.9e-08 33.4 0.0 9e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family RVP_2 PF08284.11 CDJ51411.1 - 7e-06 25.9 0.1 2.6e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CDJ51411.1 - 0.045 14.0 0.1 0.17 12.2 0.1 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease AsmA PF05170.14 CDJ51411.1 - 0.21 10.3 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 AsmA family TSP_1 PF00090.19 CDJ51412.1 - 7 7.0 11.9 0.16 12.2 3.9 2.3 2 0 0 2 2 2 0 Thrombospondin type 1 domain DUF1080 PF06439.11 CDJ51413.1 - 0.045 13.9 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) ATP-synt_C PF00137.21 CDJ51414.1 - 1.6e-06 28.4 9.5 2.9e-06 27.5 9.5 1.5 1 0 0 1 1 1 1 ATP synthase subunit C Spt20 PF12090.8 CDJ51415.1 - 0.81 9.2 24.4 0.81 9.2 24.4 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ51415.1 - 7.7 6.4 24.5 7.5 6.4 24.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ51415.1 - 8 5.3 20.9 8.2 5.2 20.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 CDJ51415.1 - 9.9 6.2 10.9 9.4 6.2 10.9 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ENTH PF01417.20 CDJ51416.1 - 0.00013 22.0 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain SUIM_assoc PF16619.5 CDJ51417.1 - 0.034 14.2 10.3 0.061 13.4 10.3 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RAP1 PF07218.11 CDJ51418.1 - 0.00063 18.2 8.7 0.00089 17.7 8.7 1.2 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Imm58 PF15581.6 CDJ51418.1 - 0.074 13.2 2.2 0.11 12.6 1.8 1.5 1 1 0 1 1 1 0 Immunity protein 58 MerR-DNA-bind PF09278.11 CDJ51418.1 - 0.082 13.5 6.2 0.24 12.0 6.2 1.8 1 0 0 1 1 1 0 MerR, DNA binding SSP160 PF06933.11 CDJ51418.1 - 5.8 5.0 11.8 6.9 4.7 11.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BaxI_1 PF12811.7 CDJ51419.1 - 0.35 10.4 5.5 0.6 9.6 5.6 1.4 1 1 0 1 1 1 0 Bax inhibitor 1 like V_ATPase_I PF01496.19 CDJ51420.1 - 3.1e-23 81.7 0.1 3.6e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Spore_coat_CotO PF14153.6 CDJ51420.1 - 0.0044 17.0 2.3 0.0057 16.6 2.3 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Presenilin PF01080.17 CDJ51420.1 - 0.031 13.1 1.0 0.042 12.6 1.0 1.1 1 0 0 1 1 1 0 Presenilin DUF2142 PF09913.9 CDJ51420.1 - 0.064 12.1 0.0 0.075 11.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) SAPS PF04499.15 CDJ51420.1 - 0.1 11.4 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Succ_CoA_lig PF13607.6 CDJ51420.1 - 0.16 11.8 7.3 0.37 10.6 7.2 1.8 1 1 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain BatD PF13584.6 CDJ51420.1 - 0.36 9.6 4.5 0.084 11.7 0.7 1.7 1 1 1 2 2 2 0 Oxygen tolerance RskA PF10099.9 CDJ51420.1 - 0.47 10.7 16.7 0.68 10.2 16.7 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2561 PF10812.8 CDJ51420.1 - 0.53 10.3 8.6 0.53 10.3 7.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2561) DUF1180 PF06679.12 CDJ51420.1 - 8.1 6.8 14.0 14 6.1 14.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) V_ATPase_I PF01496.19 CDJ51421.1 - 3.4e-20 71.6 4.4 1.2e-08 33.4 0.0 3.2 2 1 1 3 3 3 2 V-type ATPase 116kDa subunit family RskA PF10099.9 CDJ51421.1 - 2.5e-06 27.9 35.8 0.0033 17.8 0.0 3.3 2 1 0 3 3 2 2 Anti-sigma-K factor rskA DUF755 PF05501.11 CDJ51421.1 - 0.0046 17.2 25.7 0.0046 17.2 25.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF755) EPL1 PF10513.9 CDJ51421.1 - 0.0053 17.2 8.1 0.0053 17.2 8.1 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like TERB2 PF15101.6 CDJ51421.1 - 0.0054 16.8 8.3 0.0054 16.8 8.3 2.3 2 0 0 2 2 2 1 Telomere-associated protein TERB2 Ribosomal_60s PF00428.19 CDJ51421.1 - 0.03 14.9 6.2 0.03 14.9 6.2 5.1 5 1 1 6 6 4 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ51421.1 - 0.034 13.8 32.7 0.072 12.7 20.5 2.2 2 0 0 2 2 2 0 Spt20 family SMN PF06003.12 CDJ51421.1 - 0.77 9.0 5.3 1.3 8.2 5.3 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Roughex PF06020.11 CDJ51421.1 - 0.81 8.7 17.5 0.46 9.5 8.4 2.2 2 0 0 2 2 2 0 Drosophila roughex protein DUF4692 PF15763.5 CDJ51421.1 - 1.5 9.3 12.0 1.7 9.1 6.6 2.4 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DUF3801 PF12687.7 CDJ51421.1 - 2 8.5 15.0 1 9.4 8.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) ALMT PF11744.8 CDJ51421.1 - 2 7.1 5.8 4 6.1 5.8 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ51421.1 - 2.7 6.9 11.4 0.25 10.3 6.0 1.7 2 0 0 2 2 2 0 Solute carrier family 12 SR-25 PF10500.9 CDJ51421.1 - 6.8 6.2 28.3 1.1 8.8 23.2 2.2 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 CDJ51421.1 - 8.2 6.2 13.4 4.8 6.9 6.9 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 LRR_9 PF14580.6 CDJ51422.1 - 2.3e-35 121.6 5.2 9.6e-13 48.0 0.3 4.7 3 2 1 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 CDJ51422.1 - 5.5e-28 96.5 34.1 3.6e-07 29.8 0.0 8.9 6 2 3 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 CDJ51422.1 - 1.8e-24 85.4 38.7 5.6e-05 23.4 1.2 9.8 4 3 9 14 14 14 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ51422.1 - 0.0003 20.9 28.3 1.4 9.7 0.0 10.2 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_6 PF13516.6 CDJ51422.1 - 0.00058 19.7 26.6 0.58 10.4 0.6 8.9 10 1 1 11 11 11 3 Leucine Rich repeat LRR_4 PF12799.7 CDJ51423.1 - 1.1e-06 28.9 7.8 0.0084 16.5 1.5 3.2 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ51423.1 - 2.6e-06 27.1 7.0 4.4e-05 23.2 2.1 2.7 2 0 0 2 2 2 2 Leucine rich repeat PG_isomerase_N PF18353.1 CDJ51424.1 - 0.0048 17.3 0.4 0.016 15.6 0.4 1.8 1 0 0 1 1 1 1 Phosphoglucose isomerase N-terminal domain Dicty_REP PF05086.12 CDJ51424.1 - 2.3 6.1 10.2 3.2 5.6 10.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AAA_8 PF12780.7 CDJ51425.1 - 1.1e-87 293.7 0.0 5.4e-86 288.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ51425.1 - 7e-78 260.7 1.1 7e-78 260.7 1.1 3.3 5 0 0 5 5 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDJ51425.1 - 1e-64 217.4 0.0 3.2e-64 215.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynein_C PF18199.1 CDJ51425.1 - 1.1e-64 218.6 0.0 1.1e-64 218.6 0.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain MT PF12777.7 CDJ51425.1 - 3.1e-57 194.2 18.0 3.7e-56 190.6 17.7 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CDJ51425.1 - 3.8e-41 140.6 0.0 1.6e-40 138.6 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ51425.1 - 5.1e-40 136.3 0.0 9.1e-39 132.2 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CDJ51425.1 - 3.1e-24 85.5 0.9 1.1e-23 83.8 0.9 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ51425.1 - 5.2e-22 77.9 0.1 1.4e-21 76.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ51425.1 - 1.6e-11 44.4 0.0 1.6e-05 24.9 0.0 4.5 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CDJ51425.1 - 0.00055 19.2 0.0 0.11 11.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 CDJ51425.1 - 0.0016 19.0 4.4 0.0032 18.0 0.0 3.6 4 0 0 4 4 4 1 ABC transporter AAA_29 PF13555.6 CDJ51425.1 - 0.0022 17.7 0.0 0.066 13.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.6 CDJ51425.1 - 0.0039 17.2 0.0 0.027 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ51425.1 - 0.0045 17.4 0.0 0.0045 17.4 0.0 4.5 5 0 0 5 5 5 1 AAA ATPase domain AAA_22 PF13401.6 CDJ51425.1 - 0.0054 17.0 0.0 0.0054 17.0 0.0 3.6 4 0 0 4 4 2 1 AAA domain G-alpha PF00503.20 CDJ51425.1 - 0.011 15.0 5.8 0.031 13.5 0.0 3.3 3 0 0 3 3 3 0 G-protein alpha subunit AAA PF00004.29 CDJ51425.1 - 0.014 15.8 0.0 2.5 8.5 0.0 3.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CDJ51425.1 - 0.022 14.2 0.0 0.18 11.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 CDJ51425.1 - 0.047 13.9 2.0 0.5 10.5 0.0 3.7 3 1 0 3 3 3 0 AAA domain TsaE PF02367.17 CDJ51425.1 - 0.15 12.1 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 CDJ51425.1 - 0.21 11.8 0.7 1.1 9.5 0.0 2.7 3 0 0 3 3 1 0 Ras of Complex, Roc, domain of DAPkinase Retrotrans_gag PF03732.17 CDJ51425.1 - 10 6.5 10.4 1.1 9.6 0.4 4.4 5 0 0 5 5 5 0 Retrotransposon gag protein AAA_6 PF12774.7 CDJ51426.1 - 5.9e-141 469.2 0.0 1.3e-140 468.0 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CDJ51426.1 - 2.7e-111 373.0 26.6 3.7e-70 237.1 3.9 3.7 3 1 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CDJ51426.1 - 1.9e-110 369.7 12.8 1.9e-110 369.7 12.8 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 CDJ51426.1 - 3.5e-10 40.0 0.0 0.00018 21.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDJ51426.1 - 0.0063 17.1 0.0 0.24 12.0 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CDJ51426.1 - 0.017 15.6 0.0 0.14 12.6 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CDJ51426.1 - 0.024 14.6 0.1 0.66 9.9 0.1 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 CDJ51426.1 - 0.13 11.8 0.0 18 4.8 0.0 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region RAP1 PF07218.11 CDJ51426.1 - 0.14 10.4 4.8 0.33 9.2 4.8 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AAA_22 PF13401.6 CDJ51426.1 - 0.14 12.4 0.2 48 4.2 0.0 4.0 4 1 0 4 4 4 0 AAA domain BLI1 PF17324.2 CDJ51426.1 - 1.4 9.6 8.7 3.1 8.5 0.0 5.0 5 0 0 5 5 5 0 BLOC-1 interactor 1 AAA_16 PF13191.6 CDJ51426.1 - 4.4 7.7 10.3 24 5.3 0.0 5.3 4 1 1 5 5 5 0 AAA ATPase domain RskA PF10099.9 CDJ51427.1 - 3e-06 27.7 24.0 2.4e-05 24.7 5.6 31.0 2 2 15 17 17 17 3 Anti-sigma-K factor rskA DUF2339 PF10101.9 CDJ51427.1 - 0.00032 19.4 2.6 0.00032 19.4 2.6 4.7 2 1 1 3 3 3 1 Predicted membrane protein (DUF2339) RskA PF10099.9 CDJ51428.1 - 0.0023 18.3 11.7 0.0023 18.3 11.7 8.4 1 1 6 7 7 7 2 Anti-sigma-K factor rskA eIF-3_zeta PF05091.12 CDJ51428.1 - 5.4 5.9 27.9 0.74 8.7 2.4 3.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 CDJ51429.1 - 0.0048 16.5 13.1 0.0048 16.5 13.1 1.1 1 0 0 1 1 1 1 Spt20 family RskA PF10099.9 CDJ51429.1 - 0.039 14.3 10.9 0.04 14.2 10.9 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ51429.1 - 0.043 12.8 11.1 0.044 12.7 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ51429.1 - 0.08 12.9 15.0 0.08 12.9 15.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.6 CDJ51429.1 - 0.12 12.3 7.0 0.11 12.5 7.0 1.0 1 0 0 1 1 1 0 Spore coat protein CotO SARAF PF06682.12 CDJ51429.1 - 0.19 11.3 5.4 0.19 11.3 5.4 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 CDJ51429.1 - 0.22 12.5 3.1 0.22 12.5 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pex14_N PF04695.13 CDJ51429.1 - 0.54 10.9 11.6 0.51 11.0 11.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF533 PF04391.12 CDJ51429.1 - 0.69 9.5 11.1 0.72 9.4 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF533) PepSY_2 PF13670.6 CDJ51429.1 - 1.2 9.2 8.1 1.7 8.7 8.1 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain UPF0560 PF10577.9 CDJ51429.1 - 1.6 7.1 7.7 1.5 7.2 7.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Suf PF05843.14 CDJ51429.1 - 1.9 8.4 7.2 1.9 8.4 7.2 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ51429.1 - 2.3 6.9 4.1 2.1 7.1 4.1 1.0 1 0 0 1 1 1 0 Presenilin Roughex PF06020.11 CDJ51429.1 - 3.4 6.7 7.1 3.1 6.8 7.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Fusion_gly PF00523.18 CDJ51430.1 - 0.11 10.7 1.1 0.1 10.9 1.1 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF4179 PF13786.6 CDJ51431.1 - 0.42 11.1 6.6 12 6.5 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) RskA PF10099.9 CDJ51431.1 - 0.9 9.8 43.0 0.072 13.4 20.4 3.1 1 1 0 2 2 2 0 Anti-sigma-K factor rskA K_channel_TID PF07941.11 CDJ51431.1 - 3 8.4 42.7 0.51 10.8 24.2 2.9 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain NICE-1 PF15845.5 CDJ51431.1 - 3.6 8.4 10.0 1.1 10.1 0.4 2.3 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family T2SSE PF00437.20 CDJ51432.1 - 1.5e-05 24.2 0.5 1.5e-05 24.2 0.5 1.4 2 0 0 2 2 1 1 Type II/IV secretion system protein NTPase_1 PF03266.15 CDJ51432.1 - 0.0037 17.2 0.4 0.0095 15.9 0.0 1.9 2 0 0 2 2 2 1 NTPase cobW PF02492.19 CDJ51432.1 - 0.0059 16.2 0.0 0.0059 16.2 0.0 2.2 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 CDJ51432.1 - 0.012 16.0 0.0 0.012 16.0 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDJ51432.1 - 0.024 15.2 10.7 0.1 13.1 4.4 3.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CDJ51432.1 - 0.028 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pex14_N PF04695.13 CDJ51432.1 - 0.17 12.5 32.2 1 10.0 15.8 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_23 PF13476.6 CDJ51432.1 - 0.63 10.5 0.2 0.63 10.5 0.2 3.1 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 CDJ51432.1 - 0.69 9.6 0.0 0.69 9.6 0.0 2.9 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 CDJ51432.1 - 1.4 9.1 8.8 0.12 12.7 2.4 2.5 2 1 0 2 2 2 0 AAA domain ASD2 PF08687.11 CDJ51432.1 - 1.5 8.3 35.9 0.51 9.8 9.5 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Presenilin PF01080.17 CDJ51432.1 - 3.5 6.3 32.0 0.5 9.1 15.5 2.1 2 0 0 2 2 2 0 Presenilin TFIIA PF03153.13 CDJ51433.1 - 0.00077 19.6 36.8 0.00098 19.2 36.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ51433.1 - 0.013 14.6 19.3 0.016 14.3 19.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SLC12 PF03522.15 CDJ51433.1 - 1.9 7.4 19.4 2.5 7.0 19.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Slu7 PF11708.8 CDJ51433.1 - 2 8.1 25.8 3.2 7.4 3.9 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor DUF3807 PF12720.7 CDJ51433.1 - 3.2 8.0 27.4 2 8.7 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) ANAPC_CDC26 PF10471.9 CDJ51433.1 - 4.2 8.3 42.9 1.4 9.8 37.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Ndc1_Nup PF09531.10 CDJ51433.1 - 7.4 5.1 15.5 8.6 4.9 15.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Activator_LAG-3 PF11498.8 CDJ51434.1 - 0.00031 19.8 30.1 0.00031 19.8 30.1 5.5 3 2 2 5 5 5 1 Transcriptional activator LAG-3 CCSAP PF15748.5 CDJ51437.1 - 0.13 12.4 46.4 0.3 11.2 14.0 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SDA1 PF05285.12 CDJ51437.1 - 0.36 10.2 44.1 1.4 8.3 19.9 2.2 2 0 0 2 2 2 0 SDA1 U79_P34 PF03064.16 CDJ51437.1 - 1.3 8.3 40.0 0.015 14.7 11.3 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 CDC45 PF02724.14 CDJ51437.1 - 1.6 6.9 43.6 1.2 7.4 14.5 2.2 2 0 0 2 2 2 0 CDC45-like protein RskA PF10099.9 CDJ51437.1 - 7.9 6.7 20.3 1.2e+03 -0.3 20.3 2.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Vps51 PF08700.11 CDJ51438.1 - 2.4e-16 59.6 0.0 2.4e-16 59.6 0.0 3.6 4 0 0 4 4 4 1 Vps51/Vps67 COG2 PF06148.11 CDJ51438.1 - 3.1e-06 27.3 0.1 3.1e-06 27.3 0.1 3.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2722 PF10846.8 CDJ51438.1 - 0.00022 20.3 7.1 0.00022 20.3 7.1 6.3 4 3 2 6 6 6 1 Protein of unknown function (DUF2722) Sec5 PF15469.6 CDJ51438.1 - 0.00072 19.4 0.5 0.00072 19.4 0.5 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec5 SR-25 PF10500.9 CDJ51438.1 - 0.0027 17.3 12.8 0.0027 17.3 12.8 5.5 6 0 0 6 6 6 4 Nuclear RNA-splicing-associated protein DUF4064 PF13273.6 CDJ51438.1 - 0.41 11.0 0.1 0.41 11.0 0.1 5.4 4 1 1 5 5 5 0 Protein of unknown function (DUF4064) FAM150 PF15129.6 CDJ51439.1 - 0.21 11.8 16.5 0.21 11.7 16.5 1.0 1 0 0 1 1 1 0 FAM150 family Ldh_1_N PF00056.23 CDJ51441.1 - 2.4e-33 115.2 3.2 2.9e-32 111.7 1.3 3.0 2 1 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDJ51441.1 - 2.6e-31 108.8 0.0 2.6e-31 108.8 0.0 2.1 2 1 0 2 2 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 CDJ51441.1 - 0.0021 17.7 1.1 0.033 13.8 0.0 3.0 2 1 1 3 3 3 1 Family 4 glycosyl hydrolase RR_TM4-6 PF06459.12 CDJ51441.1 - 0.011 15.5 23.4 0.014 15.2 23.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ51441.1 - 0.067 12.2 28.6 0.091 11.7 28.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 CDJ51441.1 - 0.12 11.4 17.4 0.18 10.8 17.4 1.2 1 0 0 1 1 1 0 CLN3 protein SARAF PF06682.12 CDJ51441.1 - 0.13 11.9 17.8 0.17 11.5 17.8 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Pex14_N PF04695.13 CDJ51441.1 - 0.13 12.9 38.8 0.32 11.6 38.8 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CobT PF06213.12 CDJ51441.1 - 0.18 11.1 39.7 0.33 10.3 39.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DREPP PF05558.12 CDJ51441.1 - 0.21 11.5 4.7 0.34 10.8 4.7 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide DUF913 PF06025.12 CDJ51441.1 - 0.24 10.4 14.4 0.41 9.6 14.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Velvet PF11754.8 CDJ51441.1 - 0.4 10.6 21.8 0.54 10.2 21.8 1.2 1 0 0 1 1 1 0 Velvet factor Endostatin PF06482.11 CDJ51441.1 - 0.43 10.0 23.4 0.7 9.3 23.4 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SID-1_RNA_chan PF13965.6 CDJ51441.1 - 0.72 8.2 10.4 0.94 7.8 10.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CBP_BcsG PF11658.8 CDJ51441.1 - 0.85 7.9 18.1 1.2 7.4 18.1 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF2126 PF09899.9 CDJ51441.1 - 1.3 7.0 18.1 2 6.4 18.1 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) TCP PF03634.13 CDJ51441.1 - 1.3 9.5 26.3 2.1 8.9 26.3 1.2 1 0 0 1 1 1 0 TCP family transcription factor V_ATPase_I PF01496.19 CDJ51441.1 - 1.8 6.4 31.6 2.5 5.9 31.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CSG2 PF16965.5 CDJ51441.1 - 2.1 7.2 14.3 2.9 6.8 14.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Tmp39 PF10271.9 CDJ51441.1 - 3.1 6.7 8.4 4.4 6.2 8.4 1.1 1 0 0 1 1 1 0 Putative transmembrane protein PAT1 PF09770.9 CDJ51441.1 - 3.5 5.8 48.0 4.1 5.6 48.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 CDJ51441.1 - 3.8 6.4 28.3 5.4 5.9 28.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PIP5K PF01504.18 CDJ51441.1 - 3.8 6.7 19.8 5.7 6.1 19.8 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Hydin_ADK PF17213.3 CDJ51441.1 - 6 7.1 18.6 12 6.1 18.6 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_23 PF13476.6 CDJ51441.1 - 6.9 7.1 32.9 11 6.5 32.9 1.4 1 0 0 1 1 1 0 AAA domain Otopetrin PF03189.13 CDJ51441.1 - 7.5 5.2 14.2 11 4.8 14.2 1.3 1 0 0 1 1 1 0 Otopetrin WTX PF09422.10 CDJ51441.1 - 7.8 5.5 21.5 10 5.0 21.5 1.1 1 0 0 1 1 1 0 WTX protein NPR3 PF03666.13 CDJ51441.1 - 7.9 5.1 28.6 11 4.7 28.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 CDJ51441.1 - 8.1 6.4 22.3 12 5.9 22.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Connexin PF00029.19 CDJ51441.1 - 9.5 5.9 20.4 16 5.1 20.4 1.3 1 0 0 1 1 1 0 Connexin IMP2_N PF18590.1 CDJ51442.1 - 3.3e-16 59.6 0.0 5.4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain Nop14 PF04147.12 CDJ51442.1 - 0.03 12.5 10.0 0.035 12.3 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.6 CDJ51442.1 - 0.28 9.9 7.0 0.4 9.4 7.0 1.1 1 0 0 1 1 1 0 Raftlin Smg8_Smg9 PF10220.9 CDJ51442.1 - 0.34 9.2 3.7 0.46 8.7 3.7 1.1 1 0 0 1 1 1 0 Smg8_Smg9 NPR3 PF03666.13 CDJ51442.1 - 0.73 8.6 3.8 0.87 8.3 3.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ51442.1 - 1.1 7.9 8.8 1.6 7.5 8.8 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ51442.1 - 1.7 7.6 4.0 2.3 7.2 4.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Menin PF05053.13 CDJ51442.1 - 1.9 6.8 9.5 2.9 6.1 9.5 1.3 1 0 0 1 1 1 0 Menin Asp-B-Hydro_N PF05279.11 CDJ51442.1 - 2.8 7.9 19.6 5 7.1 19.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TP53IP5 PF15331.6 CDJ51442.1 - 6.1 6.9 8.6 12 5.9 8.6 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 CDC45 PF02724.14 CDJ51442.1 - 9.7 4.3 9.7 13 3.9 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 CDJ51442.1 - 10 4.1 7.1 13 3.8 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RskA PF10099.9 CDJ51443.1 - 0.0073 16.6 26.1 0.0073 16.6 26.1 20.0 1 1 15 16 16 16 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ51443.1 - 1.2 8.0 87.2 0.81 8.6 4.2 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ51444.1 - 0.02 14.9 34.8 0.032 14.2 34.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ51444.1 - 0.6 8.8 17.4 0.82 8.4 17.4 1.2 1 0 0 1 1 1 0 Presenilin PEX11 PF05648.14 CDJ51444.1 - 0.68 9.3 7.9 0.052 13.0 1.5 1.9 1 1 1 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Patatin PF01734.22 CDJ51444.1 - 1.5 8.9 8.4 1.9 8.6 8.4 1.1 1 0 0 1 1 1 0 Patatin-like phospholipase DUF4179 PF13786.6 CDJ51444.1 - 3 8.4 11.0 0.76 10.3 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) SRP-alpha_N PF04086.13 CDJ51444.1 - 3.1 7.6 21.8 3.9 7.3 21.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SLC12 PF03522.15 CDJ51444.1 - 3.3 6.6 12.8 4 6.3 12.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Apt1 PF10351.9 CDJ51444.1 - 6.1 5.6 10.5 7.6 5.3 10.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain O-antigen_lig PF13425.6 CDJ51445.1 - 0.00079 18.3 0.4 0.00094 18.1 0.4 1.0 1 0 0 1 1 1 1 O-antigen ligase like membrane protein SID-1_RNA_chan PF13965.6 CDJ51445.1 - 0.0094 14.4 2.3 0.011 14.2 2.3 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ51445.1 - 0.022 13.7 5.8 0.032 13.2 5.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1772 PF08592.11 CDJ51445.1 - 0.057 13.7 0.1 0.089 13.1 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) TFIIA PF03153.13 CDJ51445.1 - 0.11 12.4 39.0 0.16 11.9 39.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ51445.1 - 0.16 12.3 19.8 4.2 7.6 19.8 2.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA eIF-3_zeta PF05091.12 CDJ51445.1 - 0.21 10.5 13.2 0.25 10.3 13.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 CDJ51445.1 - 0.32 10.8 16.8 0.5 10.1 16.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 CDJ51445.1 - 0.51 9.7 12.3 0.62 9.4 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Afi1 PF07792.12 CDJ51445.1 - 0.59 10.6 20.2 1.4 9.4 20.2 1.6 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3357 PF11837.8 CDJ51445.1 - 0.75 10.3 5.8 2.2 8.8 5.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Pap_E4 PF02711.14 CDJ51445.1 - 0.92 10.5 14.7 7.8 7.5 11.8 2.3 2 0 0 2 2 2 0 E4 protein CLN3 PF02487.17 CDJ51445.1 - 1 8.3 8.8 1.3 8.0 8.8 1.2 1 0 0 1 1 1 0 CLN3 protein HCO3_cotransp PF00955.21 CDJ51445.1 - 1.2 7.9 2.4 1.6 7.5 2.4 1.2 1 0 0 1 1 1 0 HCO3- transporter family Cellulose_synt PF03552.14 CDJ51445.1 - 1.4 7.3 5.7 1.7 7.0 5.7 1.1 1 0 0 1 1 1 0 Cellulose synthase CSG2 PF16965.5 CDJ51445.1 - 1.7 7.5 5.7 2 7.3 5.7 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator PAT1 PF09770.9 CDJ51445.1 - 1.9 6.7 28.0 2.2 6.5 28.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Draxin PF15550.6 CDJ51445.1 - 2.3 8.0 14.2 2.9 7.7 14.2 1.1 1 0 0 1 1 1 0 Draxin Paramyxo_ncap PF00973.19 CDJ51445.1 - 2.4 7.0 12.5 2.8 6.7 12.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Peptidase_U57 PF05582.12 CDJ51445.1 - 2.6 7.2 8.2 3.7 6.7 8.2 1.3 1 0 0 1 1 1 0 YabG peptidase U57 SLC12 PF03522.15 CDJ51445.1 - 2.8 6.9 16.3 3.6 6.5 16.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 CDJ51445.1 - 4.7 5.9 12.6 5.1 5.8 12.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 CDJ51445.1 - 7.2 4.4 18.6 9.9 3.9 18.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.7 CDJ51445.1 - 7.7 4.5 16.6 8.3 4.4 16.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2828 PF11443.8 CDJ51445.1 - 8.8 4.3 17.2 11 3.9 17.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RED_N PF07808.13 CDJ51446.1 - 0.01 15.4 20.9 0.02 14.5 7.0 2.7 2 1 0 2 2 2 0 RED-like protein N-terminal region Period_C PF12114.8 CDJ51446.1 - 0.011 15.3 25.0 0.011 15.3 25.0 2.3 2 1 1 3 3 3 0 Period protein 2/3C-terminal region PI3K_1B_p101 PF10486.9 CDJ51446.1 - 0.013 13.4 29.9 0.016 13.0 29.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RAP1 PF07218.11 CDJ51446.1 - 0.95 7.7 8.2 1.1 7.4 8.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LAP1C PF05609.12 CDJ51446.1 - 1.2 8.1 31.3 1.8 7.6 31.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Polysacc_synt_4 PF04669.13 CDJ51446.1 - 2.4 7.7 7.1 22 4.5 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis Peptidase_S49_N PF08496.10 CDJ51446.1 - 2.6 8.1 23.8 0.44 10.6 2.3 3.1 3 0 0 3 3 3 0 Peptidase family S49 N-terminal CAML PF14963.6 CDJ51446.1 - 6.2 6.9 15.7 9.6 6.2 0.1 2.2 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Fer4_22 PF17179.4 CDJ51446.1 - 6.5 7.7 26.5 0.1 13.5 8.8 3.1 3 0 0 3 3 3 0 4Fe-4S dicluster domain RskA PF10099.9 CDJ51447.1 - 0.0098 16.2 32.3 0.091 13.1 21.2 2.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA PI3K_1B_p101 PF10486.9 CDJ51447.1 - 0.19 9.5 28.7 0.013 13.3 17.3 2.1 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Apt1 PF10351.9 CDJ51447.1 - 0.2 10.5 30.3 0.12 11.2 21.4 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain MAP65_ASE1 PF03999.12 CDJ51447.1 - 0.33 9.6 34.4 0.03 13.0 25.8 2.0 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) CDC45 PF02724.14 CDJ51447.1 - 0.43 8.8 15.9 0.97 7.7 13.9 1.9 2 0 0 2 2 2 0 CDC45-like protein Presenilin PF01080.17 CDJ51447.1 - 0.49 9.1 23.8 0.2 10.4 17.3 2.2 2 0 0 2 2 2 0 Presenilin V_ATPase_I PF01496.19 CDJ51447.1 - 0.5 8.2 8.0 0.75 7.6 8.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S15 PF02129.18 CDJ51447.1 - 0.84 9.2 12.0 0.048 13.2 6.9 1.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) TFIIA PF03153.13 CDJ51447.1 - 1.2 9.1 49.1 2.1 8.2 49.1 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pol_alpha_B_N PF08418.10 CDJ51447.1 - 2.4 8.1 26.1 4.9 7.0 20.4 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal NST1 PF13945.6 CDJ51447.1 - 3.4 7.7 31.6 0.033 14.3 21.1 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator Membralin PF09746.9 CDJ51447.1 - 3.7 6.5 8.4 6.5 5.7 8.4 1.4 1 0 0 1 1 1 0 Tumour-associated protein Peptidase_S49_N PF08496.10 CDJ51447.1 - 3.7 7.6 13.5 0.15 12.1 7.9 1.5 2 0 0 2 2 1 0 Peptidase family S49 N-terminal Draxin PF15550.6 CDJ51447.1 - 4.3 7.1 20.3 0.41 10.5 13.6 1.9 2 0 0 2 2 2 0 Draxin Asp-B-Hydro_N PF05279.11 CDJ51447.1 - 4.9 7.1 8.9 0.98 9.4 5.6 1.4 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region MPM1 PF17234.2 CDJ51447.1 - 5.3 7.3 20.8 0.46 10.7 15.3 2.0 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 eIF-3_zeta PF05091.12 CDJ51447.1 - 5.4 5.9 18.5 0.24 10.3 13.3 1.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MCU PF04678.13 CDJ51447.1 - 5.4 7.1 10.4 14 5.7 8.6 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Neur_chan_memb PF02932.16 CDJ51447.1 - 6.6 6.7 17.4 1.4 8.9 10.8 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ51448.1 - 0.074 13.0 44.6 0.0085 16.1 22.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 CDJ51449.1 - 0.09 12.9 62.7 0.13 12.4 62.7 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated AF-4 PF05110.13 CDJ51449.1 - 0.095 10.8 59.4 0.13 10.3 59.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3446 PF11928.8 CDJ51449.1 - 5.1 7.5 12.9 13 6.1 12.9 1.8 1 0 0 1 1 1 0 Early growth response N-terminal domain SelP_N PF04592.14 CDJ51450.1 - 0.54 9.6 57.7 0.77 9.1 57.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAM76 PF16046.5 CDJ51450.1 - 0.86 8.9 35.1 1.2 8.4 35.1 1.1 1 0 0 1 1 1 0 FAM76 protein Rtf2 PF04641.12 CDJ51450.1 - 7.4 5.9 22.1 8.3 5.7 22.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Sporozoite_P67 PF05642.11 CDJ51451.1 - 0.0046 15.1 12.4 0.0056 14.8 12.4 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF2076 PF09849.9 CDJ51451.1 - 0.0059 16.7 37.9 0.092 12.8 15.5 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2076) DUF3295 PF11702.8 CDJ51451.1 - 0.0091 15.4 16.9 0.0091 15.4 16.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3295) Spt20 PF12090.8 CDJ51451.1 - 0.015 14.9 55.7 0.16 11.6 29.6 2.3 2 0 0 2 2 2 0 Spt20 family ABC_sub_bind PF04392.12 CDJ51451.1 - 0.018 14.3 0.3 0.018 14.3 0.3 1.6 2 0 0 2 2 1 0 ABC transporter substrate binding protein Med15 PF09606.10 CDJ51451.1 - 0.12 11.1 42.3 0.15 10.7 42.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SpoIIP PF07454.11 CDJ51451.1 - 0.2 11.1 14.6 0.23 10.9 4.6 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CDJ51451.1 - 0.77 8.5 30.8 0.37 9.5 17.2 2.0 2 0 0 2 2 2 0 Presenilin Macoilin PF09726.9 CDJ51451.1 - 1.2 7.6 25.9 0.19 10.2 16.3 2.0 2 0 0 2 2 2 0 Macoilin family Connexin PF00029.19 CDJ51451.1 - 1.9 8.2 11.6 1.4 8.7 1.1 2.1 2 0 0 2 2 2 0 Connexin CPSF100_C PF13299.6 CDJ51451.1 - 2.5 8.3 16.5 0.67 10.1 6.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 CDJ51451.1 - 2.6 7.0 18.1 1.2 8.1 7.9 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Roughex PF06020.11 CDJ51451.1 - 3.1 6.8 28.4 0.079 12.0 12.6 2.1 2 0 0 2 2 2 0 Drosophila roughex protein Plasmodium_Vir PF05795.11 CDJ51451.1 - 4.2 6.7 15.2 0.14 11.5 7.8 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Membralin PF09746.9 CDJ51451.1 - 4.2 6.3 10.7 0.42 9.6 1.4 2.0 2 0 0 2 2 2 0 Tumour-associated protein EPL1 PF10513.9 CDJ51451.1 - 5.7 7.3 24.1 2.6 8.4 3.0 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF913 PF06025.12 CDJ51451.1 - 6.6 5.6 13.4 0.85 8.5 5.6 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Helicase_C PF00271.31 CDJ51452.1 - 3.7e-12 46.6 0.0 5.8e-11 42.7 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RsgA_GTPase PF03193.16 CDJ51452.1 - 0.054 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 CDJ51452.1 - 0.12 12.8 0.0 0.12 12.8 0.0 2.8 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.9 CDJ51454.1 - 0.0022 17.8 0.4 0.011 15.5 0.2 2.0 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation KCT2 PF17818.1 CDJ51457.1 - 0.026 14.6 1.5 0.026 14.6 1.5 1.8 1 1 0 2 2 2 0 Keratinocyte-associated gene product FSA_C PF10479.9 CDJ51457.1 - 0.053 11.7 2.2 0.057 11.6 2.2 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Miga PF10265.9 CDJ51457.1 - 0.07 12.1 5.5 0.074 12.0 5.5 1.0 1 0 0 1 1 1 0 Mitoguardin BAF1_ABF1 PF04684.13 CDJ51457.1 - 0.094 11.8 13.3 0.11 11.6 13.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2057 PF09829.9 CDJ51457.1 - 0.37 10.9 11.9 0.48 10.5 11.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF3138 PF11336.8 CDJ51457.1 - 0.52 8.9 14.2 0.64 8.6 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CDRT4 PF15213.6 CDJ51457.1 - 1 10.0 7.6 2.1 9.0 7.6 1.5 1 1 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Presenilin PF01080.17 CDJ51457.1 - 1.4 7.6 9.6 1.5 7.5 9.6 1.0 1 0 0 1 1 1 0 Presenilin FRQ PF09421.10 CDJ51457.1 - 1.6 6.6 9.0 1.9 6.4 9.0 1.0 1 0 0 1 1 1 0 Frequency clock protein MDM10 PF12519.8 CDJ51457.1 - 2.7 6.8 9.1 3.1 6.6 9.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4746 PF15928.5 CDJ51457.1 - 4.9 6.5 16.1 6.9 6.0 16.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DDHD PF02862.17 CDJ51457.1 - 5.2 7.2 6.4 6.3 6.9 6.4 1.2 1 0 0 1 1 1 0 DDHD domain Rota_VP2 PF05087.12 CDJ51457.1 - 6.1 4.8 9.1 7.6 4.5 9.1 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF4554 PF15091.6 CDJ51457.1 - 6.8 5.5 12.0 8.2 5.2 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DUF677 PF05055.12 CDJ51458.1 - 0.00059 18.8 4.5 0.00067 18.7 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF677) RskA PF10099.9 CDJ51458.1 - 0.06 13.6 18.9 0.079 13.2 18.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4710 PF15828.5 CDJ51458.1 - 0.064 13.4 8.2 2.5 8.3 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) DUF443 PF04276.12 CDJ51458.1 - 0.069 12.9 0.3 0.081 12.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF443) T2SSF PF00482.23 CDJ51458.1 - 0.14 12.1 3.2 0.17 11.8 3.2 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F ThiJ_like PF17124.5 CDJ51458.1 - 0.15 11.7 4.7 0.19 11.4 4.7 1.0 1 0 0 1 1 1 0 ThiJ/PfpI family-like DUF2232 PF09991.9 CDJ51458.1 - 0.16 11.1 4.3 0.18 10.9 4.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) TFIIA PF03153.13 CDJ51458.1 - 0.2 11.6 14.3 0.23 11.4 14.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.6 CDJ51458.1 - 0.41 9.8 6.6 0.48 9.6 6.6 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4179 PF13786.6 CDJ51458.1 - 0.69 10.4 16.2 5.8 7.5 16.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) TALPID3 PF15324.6 CDJ51458.1 - 0.72 7.5 17.4 0.8 7.3 17.4 1.0 1 0 0 1 1 1 0 Hedgehog signalling target DUF3112 PF11309.8 CDJ51458.1 - 0.72 9.3 2.6 0.88 9.0 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) R_equi_Vir PF05526.11 CDJ51458.1 - 1.5 8.7 12.2 1.8 8.4 12.2 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein IHABP4_N PF16174.5 CDJ51458.1 - 1.7 9.3 15.3 2.6 8.6 15.3 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Cyt_bd_oxida_I PF01654.17 CDJ51458.1 - 2.1 6.9 8.8 2.5 6.6 8.8 1.0 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I KdgT PF03812.13 CDJ51458.1 - 2.7 7.2 10.3 3.1 7.0 10.3 1.2 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease O-antigen_lig PF13425.6 CDJ51458.1 - 3.8 6.2 4.2 8.6 5.0 4.2 1.5 1 1 0 1 1 1 0 O-antigen ligase like membrane protein XRN_M PF17846.1 CDJ51458.1 - 3.8 6.4 7.6 4.6 6.1 7.6 1.0 1 0 0 1 1 1 0 Xrn1 helical domain SUIM_assoc PF16619.5 CDJ51459.1 - 5.3e-08 32.8 5.7 7.2e-05 22.8 0.0 2.7 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 tRNA-synt_1 PF00133.22 CDJ51459.1 - 0.039 12.2 0.2 4.3 5.5 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) Spt20 PF12090.8 CDJ51459.1 - 0.057 13.0 20.0 0.22 11.1 3.7 2.3 2 0 0 2 2 2 0 Spt20 family Med3 PF11593.8 CDJ51459.1 - 1.3 8.1 36.0 0.014 14.6 20.6 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF3015 PF11220.8 CDJ51459.1 - 3.9 7.3 9.6 0.16 11.8 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) PLAT PF01477.23 CDJ51460.1 - 1.7e-06 28.6 0.0 0.011 16.2 0.0 2.5 1 1 2 3 3 3 2 PLAT/LH2 domain SR-25 PF10500.9 CDJ51460.1 - 1.7e-05 24.6 20.9 2.2e-05 24.2 20.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 CDJ51460.1 - 0.0029 18.4 6.4 0.0029 18.4 6.4 1.9 3 0 0 3 3 1 1 Chorion family 2 BUD22 PF09073.10 CDJ51460.1 - 0.0091 15.4 5.4 0.011 15.2 5.4 1.1 1 0 0 1 1 1 1 BUD22 Spt20 PF12090.8 CDJ51460.1 - 0.018 14.7 10.1 0.024 14.3 10.1 1.1 1 0 0 1 1 1 0 Spt20 family CDK2AP PF09806.9 CDJ51460.1 - 0.046 13.8 14.9 0.071 13.2 14.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1635 PF07795.11 CDJ51460.1 - 0.052 13.4 11.0 0.076 12.9 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF3438 PF11920.8 CDJ51460.1 - 0.054 12.7 1.5 0.07 12.4 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Pex14_N PF04695.13 CDJ51460.1 - 0.089 13.5 9.6 0.13 12.9 9.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Coilin_N PF15862.5 CDJ51460.1 - 0.1 12.4 6.3 0.13 12.0 6.3 1.2 1 0 0 1 1 1 0 Coilin N-terminus DUF3123 PF11321.8 CDJ51460.1 - 0.12 13.1 3.1 0.16 12.6 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) CCDC106 PF15794.5 CDJ51460.1 - 0.12 12.0 12.8 0.17 11.6 12.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF1712 PF08217.11 CDJ51460.1 - 0.2 10.1 7.2 0.24 9.9 7.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Suf PF05843.14 CDJ51460.1 - 0.65 9.9 6.3 0.77 9.7 6.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Macoilin PF09726.9 CDJ51460.1 - 0.99 7.9 13.1 1.2 7.6 13.1 1.0 1 0 0 1 1 1 0 Macoilin family CCSAP PF15748.5 CDJ51460.1 - 1.1 9.3 13.7 1.8 8.7 13.7 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Apt1 PF10351.9 CDJ51460.1 - 1.1 8.0 12.5 1.4 7.7 12.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.13 CDJ51460.1 - 3.2 8.4 23.8 6.2 7.4 23.8 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DUF4614 PF15391.6 CDJ51460.1 - 3.3 7.7 21.3 5 7.1 21.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Presenilin PF01080.17 CDJ51460.1 - 3.7 6.2 9.4 4.5 5.9 9.4 1.1 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.6 CDJ51460.1 - 4.2 7.3 7.5 6.6 6.6 7.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF4834 PF16118.5 CDJ51460.1 - 4.4 8.3 5.6 7.7 7.5 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RAP1 PF07218.11 CDJ51460.1 - 7.2 4.8 13.0 9 4.4 13.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Corona_nucleoca PF00937.18 CDJ51460.1 - 10 5.1 13.1 13 4.7 13.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SR-25 PF10500.9 CDJ51462.1 - 0.0042 16.7 26.5 0.0042 16.7 26.5 2.0 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ51463.1 - 0.007 16.7 5.1 0.009 16.3 5.1 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ51463.1 - 0.02 14.9 7.8 0.021 14.8 7.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Laminin_G_3 PF13385.6 CDJ51463.1 - 0.026 14.7 0.1 0.069 13.3 0.0 1.8 2 1 1 3 3 3 0 Concanavalin A-like lectin/glucanases superfamily DUF2722 PF10846.8 CDJ51463.1 - 0.13 11.2 6.5 0.15 10.9 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ51463.1 - 0.17 11.4 12.7 0.23 11.1 12.7 1.1 1 0 0 1 1 1 0 Spt20 family Prp31_C PF09785.9 CDJ51465.1 - 4.8e-19 69.5 10.6 1e-18 68.4 8.3 2.3 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.18 CDJ51465.1 - 1.1e-07 31.5 0.6 0.00066 19.2 0.2 3.2 3 1 0 3 3 3 2 snoRNA binding domain, fibrillarin TrbI PF03743.14 CDJ51465.1 - 0.13 12.1 0.7 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein EVI2A PF05399.11 CDJ51466.1 - 0.023 14.3 0.2 0.023 14.3 0.2 3.0 3 1 0 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) Otopetrin PF03189.13 CDJ51466.1 - 0.19 10.5 3.0 0.39 9.5 3.0 1.5 1 0 0 1 1 1 0 Otopetrin DUF3782 PF12644.7 CDJ51466.1 - 1.2 9.3 3.4 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) DUF4064 PF13273.6 CDJ51466.1 - 2.7 8.3 5.2 1.4 9.2 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Orf78 PF06024.12 CDJ51466.1 - 3 8.2 7.4 0.61 10.4 0.4 2.9 1 1 1 2 2 2 0 Orf78 (ac78) Connexin PF00029.19 CDJ51466.1 - 3.6 7.3 4.2 6.4 6.5 4.2 1.4 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 CDJ51466.1 - 3.9 6.4 6.0 8.4 5.3 6.0 1.5 1 0 0 1 1 1 0 CLN3 protein Tmemb_cc2 PF10267.9 CDJ51466.1 - 4.3 6.4 22.4 0.37 9.9 6.8 2.6 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein SR-25 PF10500.9 CDJ51467.1 - 0.0006 19.5 3.8 0.0006 19.5 3.8 6.1 3 2 3 6 6 6 3 Nuclear RNA-splicing-associated protein DUF3563 PF12086.8 CDJ51468.1 - 0.12 12.2 0.9 0.62 9.8 0.9 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) Connexin PF00029.19 CDJ51468.1 - 0.36 10.6 7.9 0.89 9.3 7.9 1.9 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 CDJ51468.1 - 0.44 8.9 6.3 0.69 8.2 6.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ribos_L4_asso_C PF14374.6 CDJ51469.1 - 4.1e-15 55.6 3.0 4.1e-15 55.6 3.0 4.5 4 1 1 5 5 5 1 60S ribosomal protein L4 C-terminal domain RskA PF10099.9 CDJ51469.1 - 0.00029 21.2 13.6 0.00029 21.2 13.6 3.6 2 1 1 3 3 3 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ51469.1 - 0.0082 17.1 1.7 0.0082 17.1 1.7 5.5 4 1 1 5 5 5 1 Domain of unknown function (DUF4834) Filament_head PF04732.14 CDJ51469.1 - 0.75 10.7 36.8 5.5 7.9 19.7 2.8 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Macoilin PF09726.9 CDJ51469.1 - 2.5 6.6 44.5 0.17 10.4 17.6 2.3 2 0 0 2 2 2 0 Macoilin family DUF2486 PF10667.9 CDJ51470.1 - 0.74 10.0 25.6 0.9 9.7 25.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) CCSAP PF15748.5 CDJ51470.1 - 3 7.9 10.2 4.9 7.3 10.2 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Thioredoxin PF00085.20 CDJ51471.1 - 0.00016 21.6 0.0 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin BUD22 PF09073.10 CDJ51471.1 - 0.0027 17.1 1.7 0.0054 16.1 1.7 1.5 1 0 0 1 1 1 1 BUD22 DUF4667 PF15700.5 CDJ51471.1 - 0.04 14.0 6.0 0.07 13.2 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) FAM117 PF15388.6 CDJ51471.1 - 0.2 11.1 11.5 0.86 9.0 0.1 2.4 2 0 0 2 2 2 0 Protein Family FAM117 Secretin_N_2 PF07655.13 CDJ51471.1 - 0.58 10.7 12.1 1 9.9 12.1 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain PAP1 PF08601.10 CDJ51471.1 - 2.7 7.6 15.6 6.4 6.4 15.6 1.6 1 0 0 1 1 1 0 Transcription factor PAP1 SPX PF03105.19 CDJ51471.1 - 3 7.7 8.0 0.72 9.7 4.6 1.6 2 0 0 2 2 2 0 SPX domain Sporozoite_P67 PF05642.11 CDJ51471.1 - 6.5 4.7 16.2 12 3.8 16.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen KOW PF00467.29 CDJ51472.1 - 1.9e-06 27.6 4.0 0.041 13.9 1.5 3.7 3 0 0 3 3 3 2 KOW motif DUF2722 PF10846.8 CDJ51472.1 - 2.3e-05 23.6 8.9 2.3e-05 23.6 8.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ51472.1 - 3.3e-05 24.1 12.6 3.3e-05 24.1 12.6 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 CDJ51472.1 - 0.0007 20.0 1.6 0.0007 20.0 1.6 1.8 2 0 0 2 2 2 1 Enhancer of polycomb-like EIIBC-GUT_N PF03612.14 CDJ51472.1 - 0.0077 16.0 3.3 0.0077 16.0 3.3 2.1 2 0 0 2 2 2 1 Sorbitol phosphotransferase enzyme II N-terminus DUF5568 PF17724.1 CDJ51472.1 - 0.012 15.5 2.3 0.023 14.5 2.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5568) Pex14_N PF04695.13 CDJ51472.1 - 0.015 15.9 10.8 0.015 15.9 10.8 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mak10 PF04112.13 CDJ51472.1 - 0.018 14.6 1.6 0.029 13.9 1.6 1.3 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DOCK_N PF16172.5 CDJ51472.1 - 0.033 13.1 5.0 0.052 12.5 5.0 1.2 1 0 0 1 1 1 0 DOCK N-terminus DUF4471 PF14740.6 CDJ51472.1 - 0.064 12.5 2.9 0.04 13.2 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) CDRT4 PF15213.6 CDJ51472.1 - 0.098 13.3 0.2 0.22 12.1 0.2 1.5 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein DDHD PF02862.17 CDJ51472.1 - 0.24 11.6 6.3 0.035 14.3 0.9 2.1 2 0 0 2 2 2 0 DDHD domain Shadoo PF14999.6 CDJ51472.1 - 0.33 11.1 20.5 0.56 10.3 4.8 2.6 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective V_ATPase_I PF01496.19 CDJ51472.1 - 0.34 8.8 5.3 0.57 8.0 5.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 CDJ51472.1 - 0.35 9.9 1.5 0.71 8.9 1.5 1.4 1 0 0 1 1 1 0 CLN3 protein G0-G1_switch_2 PF15103.6 CDJ51472.1 - 0.51 10.8 14.8 0.091 13.2 7.5 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 Neur_chan_memb PF02932.16 CDJ51472.1 - 0.69 9.9 3.7 1.4 8.9 3.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MCU PF04678.13 CDJ51472.1 - 0.76 9.9 5.5 0.38 10.9 1.7 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Connexin PF00029.19 CDJ51472.1 - 0.78 9.4 3.4 1.3 8.7 3.4 1.3 1 0 0 1 1 1 0 Connexin CCDC53 PF10152.9 CDJ51472.1 - 0.81 10.1 11.2 1.2 9.6 4.9 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex OATP PF03137.20 CDJ51472.1 - 0.94 7.7 2.2 1.4 7.1 2.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EOS1 PF12326.8 CDJ51472.1 - 3.3 7.6 5.6 0.74 9.7 2.3 1.5 2 0 0 2 2 1 0 N-glycosylation protein DUF1840 PF08895.11 CDJ51472.1 - 5.8 7.3 14.5 0.82 10.0 3.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Presenilin PF01080.17 CDJ51472.1 - 6.1 5.5 11.6 0.074 11.8 4.0 1.6 2 0 0 2 2 2 0 Presenilin OmpH PF03938.14 CDJ51472.1 - 6.4 7.1 38.1 0.55 10.6 16.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DAP10 PF07213.11 CDJ51473.1 - 0.055 13.4 0.4 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 DAP10 membrane protein PolyA_pol_RNAbd PF12627.7 CDJ51475.1 - 0.093 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A ATP-synt_D PF01813.17 CDJ51480.1 - 1.1e-57 195.0 1.8 1.1e-57 195.0 1.8 1.3 2 0 0 2 2 2 1 ATP synthase subunit D GREB1 PF15782.5 CDJ51481.1 - 0.67 7.0 13.0 0.74 6.9 13.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF508 PF04370.12 CDJ51481.1 - 1.4 8.6 6.9 2.8 7.6 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Pkinase PF00069.25 CDJ51482.1 - 6.6e-24 84.7 0.0 8.7e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ51482.1 - 4e-12 46.0 0.0 5.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ51482.1 - 0.0022 17.3 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDJ51482.1 - 0.0022 17.6 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CDJ51482.1 - 0.017 15.1 0.0 0.017 15.1 0.0 3.2 2 2 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 CDJ51482.1 - 0.14 11.7 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Roughex PF06020.11 CDJ51482.1 - 1.1 8.3 3.8 1.8 7.6 3.8 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF4484 PF14831.6 CDJ51483.1 - 0.0011 19.1 4.7 0.0011 19.1 4.7 7.7 5 2 2 8 8 8 1 Domain of unknown function (DUF4484) BHD_3 PF10405.9 CDJ51484.1 - 8.1e-06 26.2 0.0 3e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 CDJ51484.1 - 1.5e-05 24.7 0.1 1.5e-05 24.7 0.1 6.3 8 0 0 8 8 8 2 Rad4 transglutaminase-like domain Spt20 PF12090.8 CDJ51485.1 - 0.00034 20.3 32.7 0.0015 18.2 6.9 11.0 8 3 0 9 9 9 4 Spt20 family DUF2722 PF10846.8 CDJ51485.1 - 0.0036 16.3 3.2 0.0036 16.3 3.2 11.4 10 2 1 11 11 11 6 Protein of unknown function (DUF2722) RPAP1_C PF08620.10 CDJ51486.1 - 4.4e-17 61.9 0.1 4.4e-17 61.9 0.1 2.7 3 0 0 3 3 3 1 RPAP1-like, C-terminal Peptidase_M16_C PF05193.21 CDJ51487.1 - 1.2e-12 48.2 0.0 8.2e-12 45.5 0.0 2.4 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDJ51487.1 - 0.00045 20.2 0.0 0.0022 18.0 0.0 2.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF4179 PF13786.6 CDJ51487.1 - 0.47 11.0 0.0 0.47 11.0 0.0 6.1 5 2 0 5 5 5 0 Domain of unknown function (DUF4179) AAR2 PF05282.11 CDJ51488.1 - 1.3e-19 70.9 24.1 4.1e-09 36.3 19.7 4.0 2 1 0 2 2 2 2 AAR2 protein Utp14 PF04615.13 CDJ51488.1 - 0.0021 16.8 17.9 0.0021 16.8 17.9 2.5 1 1 1 2 2 2 1 Utp14 protein SR-25 PF10500.9 CDJ51488.1 - 0.37 10.4 48.6 0.11 12.0 8.9 4.1 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ51488.1 - 2.1 8.9 33.7 0.056 14.0 6.1 3.7 3 0 0 3 3 3 0 TCP family transcription factor Secretin_N_2 PF07655.13 CDJ51488.1 - 4.7 7.8 23.2 0.45 11.1 10.7 3.2 3 0 0 3 3 3 0 Secretin N-terminal domain OHA PF14418.6 CDJ51489.1 - 2e-14 53.2 0.2 1.7e-13 50.2 0.0 2.8 2 1 1 3 3 3 1 OST-HTH Associated domain RskA PF10099.9 CDJ51489.1 - 3e-05 24.4 11.7 3e-05 24.4 11.7 8.9 2 2 4 6 6 6 2 Anti-sigma-K factor rskA OST-HTH PF12872.7 CDJ51489.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Pex14_N PF04695.13 CDJ51490.1 - 0.053 14.2 21.4 0.069 13.8 21.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDRGK PF09756.9 CDJ51490.1 - 0.29 10.7 16.2 0.27 10.8 16.2 1.1 1 0 0 1 1 1 0 DDRGK domain UPF0524 PF15823.5 CDJ51490.1 - 0.3 10.4 10.9 0.3 10.4 10.9 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 DUF2722 PF10846.8 CDJ51490.1 - 0.41 9.5 34.3 0.52 9.2 34.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ51490.1 - 0.49 10.0 47.3 0.57 9.7 47.3 1.2 1 0 0 1 1 1 0 Spt20 family MPM1 PF17234.2 CDJ51490.1 - 0.83 9.9 18.1 0.88 9.8 18.1 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 TERB2 PF15101.6 CDJ51490.1 - 2.7 8.0 25.5 2.8 7.9 25.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ATG22 PF11700.8 CDJ51490.1 - 2.7 6.5 8.1 2.8 6.5 8.1 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Asparaginase_2 PF01112.18 CDJ51490.1 - 3.1 6.7 13.9 3.3 6.7 13.9 1.0 1 0 0 1 1 1 0 Asparaginase EIIBC-GUT_N PF03612.14 CDJ51490.1 - 3.3 7.4 17.0 3.6 7.3 17.0 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SpoIIP PF07454.11 CDJ51490.1 - 3.4 7.0 18.4 3.4 7.0 18.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 CDJ51490.1 - 3.6 7.3 12.9 3.5 7.3 12.9 1.1 1 0 0 1 1 1 0 Connexin DUF4770 PF15994.5 CDJ51490.1 - 3.7 7.7 15.8 3.8 7.7 15.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF819 PF05684.12 CDJ51490.1 - 3.7 6.5 6.0 4.3 6.3 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF819) eIF-3_zeta PF05091.12 CDJ51490.1 - 3.8 6.4 22.6 3.7 6.4 22.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM176 PF14851.6 CDJ51490.1 - 4.1 7.1 13.0 4.3 7.0 13.0 1.1 1 0 0 1 1 1 0 FAM176 family FAM76 PF16046.5 CDJ51490.1 - 4.6 6.5 21.0 4.6 6.5 21.0 1.0 1 0 0 1 1 1 0 FAM76 protein Ferlin_C PF16165.5 CDJ51490.1 - 4.8 7.1 6.3 4.7 7.1 6.3 1.1 1 0 0 1 1 1 0 Ferlin C-terminus Peptidase_S49_N PF08496.10 CDJ51490.1 - 5.4 7.1 12.4 5.6 7.0 12.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MMR1 PF08505.10 CDJ51490.1 - 5.5 7.2 25.9 5.5 7.2 25.9 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Afi1 PF07792.12 CDJ51490.1 - 5.6 7.5 15.7 5.8 7.4 15.7 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SelP_N PF04592.14 CDJ51490.1 - 5.9 6.2 16.2 6 6.2 16.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Paf1 PF03985.13 CDJ51490.1 - 6.9 5.6 21.0 7 5.5 21.0 1.1 1 0 0 1 1 1 0 Paf1 NST1 PF13945.6 CDJ51490.1 - 7 6.7 29.1 7.3 6.7 29.1 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator MMU163 PF17119.5 CDJ51490.1 - 7.7 5.6 12.1 7.8 5.6 12.1 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis CDC45 PF02724.14 CDJ51490.1 - 8.2 4.6 15.8 7.8 4.6 15.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Ion_trans PF00520.31 CDJ51491.1 - 2.1e-08 33.7 6.0 0.00014 21.2 0.1 2.7 2 1 1 3 3 3 2 Ion transport protein RskA PF10099.9 CDJ51491.1 - 0.0018 18.6 2.4 0.0018 18.6 2.4 8.1 3 2 3 6 6 6 2 Anti-sigma-K factor rskA DUF2981 PF11200.8 CDJ51491.1 - 0.052 13.3 0.2 0.052 13.3 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2981) Zip PF02535.22 CDJ51491.1 - 2.5 7.2 31.0 0.22 10.7 0.4 3.6 3 1 0 3 3 3 0 ZIP Zinc transporter PAP_assoc PF03828.19 CDJ51492.1 - 0.0081 16.3 0.1 0.0081 16.3 0.1 3.3 4 0 0 4 4 4 1 Cid1 family poly A polymerase TCP PF03634.13 CDJ51492.1 - 0.019 15.5 18.0 0.019 15.5 18.0 2.7 3 0 0 3 3 3 0 TCP family transcription factor MCU PF04678.13 CDJ51492.1 - 1.8 8.7 24.2 1.7 8.7 3.6 2.7 2 0 0 2 2 2 0 Mitochondrial calcium uniporter SPX PF03105.19 CDJ51492.1 - 3.3 7.5 35.0 0.016 15.2 15.8 2.2 2 0 0 2 2 2 0 SPX domain TFIIA PF03153.13 CDJ51492.1 - 3.8 7.4 67.3 0.021 14.8 30.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DASH_Spc34 PF08657.10 CDJ51492.1 - 8.7 6.1 34.0 0.17 11.6 6.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 RskA PF10099.9 CDJ51493.1 - 0.0014 19.0 2.7 0.0014 19.0 2.7 12.9 3 3 6 9 9 9 3 Anti-sigma-K factor rskA NTP_transf_2 PF01909.23 CDJ51493.1 - 0.0017 18.6 0.0 0.0041 17.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Sin_N PF04801.13 CDJ51493.1 - 0.0022 17.3 0.0 0.0022 17.3 0.0 7.1 4 3 1 5 5 5 1 Sin-like protein conserved region Polbeta PF18765.1 CDJ51493.1 - 0.023 14.8 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase RAB3GAP2_N PF14655.6 CDJ51494.1 - 0.0029 17.0 5.0 0.0029 17.0 5.0 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus MecA PF05389.12 CDJ51494.1 - 0.0041 16.8 3.0 0.0041 16.8 3.0 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) Tic110 PF16940.5 CDJ51494.1 - 0.0055 15.3 11.0 0.0059 15.2 11.0 1.1 1 0 0 1 1 1 1 Chloroplast envelope transporter TraT PF05818.12 CDJ51494.1 - 0.013 15.2 13.9 0.019 14.6 13.9 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein TPP_enzyme_N PF02776.18 CDJ51494.1 - 0.027 14.1 16.8 0.04 13.5 16.8 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF3093 PF11292.8 CDJ51494.1 - 0.041 14.2 5.0 0.048 13.9 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) DUF2232 PF09991.9 CDJ51494.1 - 0.043 13.0 6.7 0.059 12.6 6.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SBP_bac_5 PF00496.22 CDJ51494.1 - 0.05 12.6 11.0 0.056 12.4 11.0 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle E7 PF00527.18 CDJ51494.1 - 0.052 13.7 5.6 0.072 13.3 5.6 1.2 1 0 0 1 1 1 0 E7 protein, Early protein DUF719 PF05334.13 CDJ51494.1 - 0.075 13.2 6.4 0.094 12.9 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) FAM199X PF15814.5 CDJ51494.1 - 0.076 12.1 6.2 0.092 11.8 6.2 1.0 1 0 0 1 1 1 0 Protein family FAM199X Serinc PF03348.15 CDJ51494.1 - 0.096 11.6 3.2 0.1 11.5 3.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4834 PF16118.5 CDJ51494.1 - 0.11 13.5 3.9 0.15 13.0 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CD20 PF04103.15 CDJ51494.1 - 0.11 12.6 3.5 0.2 11.7 3.5 1.5 1 1 0 1 1 1 0 CD20-like family FHIPEP PF00771.20 CDJ51494.1 - 0.14 10.6 8.1 0.16 10.4 8.1 1.0 1 0 0 1 1 1 0 FHIPEP family FUN14 PF04930.15 CDJ51494.1 - 0.15 12.5 5.1 0.1 13.0 3.9 1.4 1 1 0 1 1 1 0 FUN14 family DUF2722 PF10846.8 CDJ51494.1 - 0.19 10.7 16.6 0.26 10.2 16.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ51494.1 - 0.32 11.0 31.0 0.35 10.8 31.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF726 PF05277.12 CDJ51494.1 - 0.38 9.6 8.0 0.43 9.5 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) RuvC_III PF18541.1 CDJ51494.1 - 0.45 10.4 7.8 0.66 9.9 7.8 1.2 1 0 0 1 1 1 0 RuvC endonuclease subdomain 3 RskA PF10099.9 CDJ51494.1 - 0.47 10.7 38.3 3.2 8.0 23.9 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA UPF0560 PF10577.9 CDJ51494.1 - 0.59 8.6 14.0 0.69 8.3 14.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Helicase_RecD PF05127.14 CDJ51494.1 - 0.95 9.3 12.2 1.3 8.8 12.2 1.3 1 1 0 1 1 1 0 Helicase ST7 PF04184.12 CDJ51494.1 - 1.1 7.7 9.4 1.3 7.4 9.4 1.0 1 0 0 1 1 1 0 ST7 protein P5-ATPase PF12409.8 CDJ51494.1 - 1.1 9.4 3.9 1.6 8.8 3.9 1.2 1 0 0 1 1 1 0 P5-type ATPase cation transporter Paramyxo_ncap PF00973.19 CDJ51494.1 - 1.1 8.1 7.6 1.3 7.9 7.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF2298 PF10060.9 CDJ51494.1 - 2 7.0 9.6 2.3 6.8 9.6 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) HemX PF04375.14 CDJ51494.1 - 2.1 7.5 25.1 2.8 7.1 25.1 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Med15 PF09606.10 CDJ51494.1 - 3.2 6.3 27.1 4.4 5.9 27.1 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal NDUF_B5 PF09781.9 CDJ51494.1 - 4.1 7.0 9.8 2.9 7.5 8.6 1.3 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit DUF3450 PF11932.8 CDJ51494.1 - 6.2 6.0 24.4 8.3 5.6 24.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PP2C_2 PF13672.6 CDJ51494.1 - 6.8 6.3 14.8 8.8 5.9 14.8 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C SUIM_assoc PF16619.5 CDJ51496.1 - 0.0037 17.3 5.4 0.0037 17.3 5.4 3.3 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Serinc PF03348.15 CDJ51496.1 - 0.94 8.3 3.5 1.3 7.8 3.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) MMR1 PF08505.10 CDJ51496.1 - 2 8.7 16.1 2.8 8.1 16.1 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Hid1 PF12722.7 CDJ51496.1 - 2.7 6.0 10.7 3.3 5.7 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.13 CDJ51496.1 - 7.9 6.3 33.6 11 5.8 33.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ51496.1 - 9.4 6.1 17.0 18 5.2 17.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 CDJ51497.1 - 0.013 16.4 4.0 0.013 16.4 4.0 7.8 5 3 2 7 7 7 0 Domain of unknown function (DUF4834) DUF2681 PF10883.8 CDJ51498.1 - 0.0024 18.2 0.4 0.0024 18.2 0.4 17.7 19 1 1 20 20 20 1 Protein of unknown function (DUF2681) SPX PF03105.19 CDJ51498.1 - 0.008 16.1 0.2 0.008 16.1 0.2 14.6 8 6 0 9 9 9 4 SPX domain RCC1 PF00415.18 CDJ51501.1 - 3.4e-13 50.0 19.7 1.8e-08 34.8 0.5 5.8 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ51501.1 - 8.3e-05 22.3 14.3 0.047 13.5 3.6 3.9 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat zf-RanBP PF00641.18 CDJ51501.1 - 0.00066 18.9 7.6 0.0013 18.0 7.6 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Spt20 PF12090.8 CDJ51501.1 - 0.0096 15.6 3.1 0.0096 15.6 3.1 10.3 6 2 1 8 8 8 3 Spt20 family TMEM132D_C PF15706.5 CDJ51504.1 - 0.013 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Noelin-1 PF12308.8 CDJ51504.1 - 0.25 11.4 0.9 0.83 9.7 0.3 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein Nup88 PF10168.9 CDJ51504.1 - 0.39 8.5 2.1 0.56 7.9 2.1 1.1 1 0 0 1 1 1 0 Nuclear pore component Snapin_Pallidin PF14712.6 CDJ51504.1 - 0.95 9.9 2.8 1.1 9.7 1.4 1.9 2 0 0 2 2 2 0 Snapin/Pallidin Metallophos PF00149.28 CDJ51505.1 - 1.3e-06 29.1 0.0 3e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Alpha_GJ PF03229.13 CDJ51505.1 - 0.74 10.4 7.9 2.8 8.5 7.9 2.0 1 0 0 1 1 1 0 Alphavirus glycoprotein J PP2C PF00481.21 CDJ51506.1 - 1.2e-44 152.9 0.2 1.2e-44 152.9 0.2 2.6 2 1 1 3 3 3 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ51506.1 - 0.0027 17.7 0.0 0.054 13.4 0.0 2.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) UPF0225 PF17775.1 CDJ51506.1 - 0.12 13.2 2.3 0.3 11.9 0.0 2.6 2 0 0 2 2 2 0 UPF0225 domain SPX PF03105.19 CDJ51506.1 - 8.5 6.2 36.0 5.2 6.9 22.5 2.3 2 0 0 2 2 2 0 SPX domain HABP4_PAI-RBP1 PF04774.15 CDJ51507.1 - 2.8e-12 47.5 12.0 2.8e-12 47.5 12.0 2.6 2 1 0 2 2 2 1 Hyaluronan / mRNA binding family TFIIA PF03153.13 CDJ51507.1 - 0.023 14.7 21.4 0.036 14.1 21.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CEP44 PF15007.6 CDJ51508.1 - 2.4e-35 121.5 9.5 1.1e-21 77.3 0.0 3.5 2 1 1 3 3 3 2 Centrosomal spindle body, CEP44 SUIM_assoc PF16619.5 CDJ51508.1 - 0.0058 16.7 7.1 0.0058 16.7 7.1 12.4 7 2 2 9 9 9 4 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 CDJ51509.1 - 2e-06 27.7 26.1 0.71 10.0 4.7 6.0 5 2 0 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 AF-4 PF05110.13 CDJ51509.1 - 3.6e-06 25.4 11.5 3.6e-06 25.4 11.5 4.1 4 0 0 4 4 4 1 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ51509.1 - 0.0099 15.5 18.6 0.0099 15.5 18.6 4.3 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein Utp14 PF04615.13 CDJ51509.1 - 0.63 8.6 18.1 0.068 11.7 9.1 2.2 2 0 0 2 2 2 0 Utp14 protein SR-25 PF10500.9 CDJ51510.1 - 0.0042 16.7 19.7 0.0042 16.7 19.7 2.6 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein DUF815 PF05673.13 CDJ51510.1 - 0.035 13.3 0.1 0.065 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.12 CDJ51510.1 - 0.42 10.4 4.4 2.5 7.9 0.1 2.9 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein Presenilin PF01080.17 CDJ51510.1 - 2.9 6.6 8.7 2.7 6.6 4.9 2.0 2 0 0 2 2 2 0 Presenilin TSA PF03249.13 CDJ51510.1 - 6.4 5.5 16.5 1.1 7.9 3.7 2.4 2 0 0 2 2 2 0 Type specific antigen eIF-3c_N PF05470.12 CDJ51511.1 - 1.9 6.7 9.7 2.5 6.3 9.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CytochromB561_N PF09786.9 CDJ51511.1 - 2.4 7.0 29.9 2.6 6.9 29.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal PPP4R2 PF09184.11 CDJ51511.1 - 8.6 5.9 24.8 11 5.5 24.8 1.2 1 0 0 1 1 1 0 PPP4R2 RNase_H2_suC PF08615.11 CDJ51513.1 - 0.03 14.5 7.6 0.23 11.7 0.0 3.3 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Mut7-C PF01927.16 CDJ51513.1 - 0.27 11.3 3.3 0.91 9.6 3.3 1.9 1 0 0 1 1 1 0 Mut7-C RNAse domain Mss4 PF04421.13 CDJ51513.1 - 3 8.0 0.0 3 8.0 0.0 3.8 4 0 0 4 4 4 0 Mss4 protein AP2 PF00847.20 CDJ51514.1 - 1.5e-11 44.3 0.2 1.5e-10 41.1 0.2 2.9 1 0 0 1 1 1 1 AP2 domain Glyco_hydro_9 PF00759.19 CDJ51516.1 - 0.057 12.8 0.7 0.061 12.7 0.7 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 YajC PF02699.15 CDJ51516.1 - 0.38 10.7 2.3 0.72 9.8 2.3 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Auto_anti-p27 PF06677.12 CDJ51517.1 - 2.1e-16 59.8 2.7 4.3e-16 58.8 2.7 1.5 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ASD2 PF08687.11 CDJ51517.1 - 0.0032 17.1 18.4 0.0032 17.1 18.4 2.1 1 1 1 2 2 2 1 Apx/Shroom domain ASD2 Lar_restr_allev PF14354.6 CDJ51517.1 - 0.44 11.0 3.0 0.37 11.2 0.9 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar Utp14 PF04615.13 CDJ51518.1 - 2 6.9 27.8 2.7 6.5 27.8 1.2 1 0 0 1 1 1 0 Utp14 protein RskA PF10099.9 CDJ51520.1 - 4e-06 27.3 8.2 1e-05 25.9 8.2 1.8 1 1 0 1 1 1 1 Anti-sigma-K factor rskA DUF4813 PF16072.5 CDJ51520.1 - 0.034 13.8 16.7 0.045 13.4 16.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Utp14 PF04615.13 CDJ51520.1 - 0.89 8.1 28.2 1.2 7.6 28.2 1.1 1 0 0 1 1 1 0 Utp14 protein DUF4820 PF16091.5 CDJ51520.1 - 4.3 6.6 23.3 0.64 9.3 5.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) FHIPEP PF00771.20 CDJ51520.1 - 8.5 4.7 8.9 2.1 6.7 4.9 1.8 2 0 0 2 2 2 0 FHIPEP family YL1 PF05764.13 CDJ51521.1 - 0.0073 16.4 12.2 0.0073 16.4 12.2 5.8 3 1 2 5 5 5 1 YL1 nuclear protein Nop53 PF07767.11 CDJ51522.1 - 6.9 6.0 52.7 33 3.7 0.0 2.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Peptidase_S15 PF02129.18 CDJ51523.1 - 5.9e-07 29.3 0.1 5.9e-07 29.3 0.1 7.3 2 2 3 5 5 5 2 X-Pro dipeptidyl-peptidase (S15 family) Auxin_canalis PF05703.11 CDJ51523.1 - 0.011 15.6 29.4 0.011 15.6 29.4 4.6 2 1 3 5 5 5 0 Auxin canalisation Auxin_canalis PF05703.11 CDJ51524.1 - 0.022 14.7 25.2 0.031 14.2 25.2 1.2 1 0 0 1 1 1 0 Auxin canalisation Hist_deacetyl PF00850.19 CDJ51524.1 - 0.068 12.6 5.5 0.13 11.7 5.6 1.5 1 1 0 1 1 1 0 Histone deacetylase domain CRT10 PF08728.10 CDJ51524.1 - 0.15 10.2 11.1 0.15 10.2 11.1 1.1 1 0 0 1 1 1 0 CRT10 SLC12 PF03522.15 CDJ51524.1 - 0.28 10.2 23.9 0.36 9.8 23.9 1.3 1 0 0 1 1 1 0 Solute carrier family 12 ABC2_membrane_3 PF12698.7 CDJ51524.1 - 1.2 8.2 4.9 1.5 7.9 4.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SOG2 PF10428.9 CDJ51524.1 - 1.2 8.3 24.4 1.6 7.9 24.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Hid1 PF12722.7 CDJ51524.1 - 2.1 6.3 28.5 2.8 5.9 28.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hamartin PF04388.12 CDJ51524.1 - 2.4 6.7 25.0 2.7 6.5 25.0 1.1 1 0 0 1 1 1 0 Hamartin protein PPP4R2 PF09184.11 CDJ51524.1 - 3.5 7.1 13.2 4.7 6.7 13.2 1.2 1 0 0 1 1 1 0 PPP4R2 FAM60A PF15396.6 CDJ51524.1 - 4.8 7.1 23.1 7.3 6.5 23.1 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Adaptin_binding PF10199.9 CDJ51524.1 - 5.5 7.6 25.1 1.4 9.6 8.8 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 N1221 PF07923.13 CDJ51525.1 - 0.033 13.4 6.0 1.3 8.1 1.6 2.2 2 0 0 2 2 2 0 N1221-like protein Eapp_C PF10238.9 CDJ51525.1 - 0.088 12.9 14.6 0.29 11.2 7.1 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein GPI2 PF06432.11 CDJ51525.1 - 0.14 11.6 0.2 10 5.4 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase SART-1 PF03343.13 CDJ51525.1 - 0.17 10.4 15.6 0.2 10.2 15.6 1.1 1 0 0 1 1 1 0 SART-1 family NST1 PF13945.6 CDJ51525.1 - 0.18 11.9 21.2 0.8 9.8 11.9 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator CD20 PF04103.15 CDJ51525.1 - 0.53 10.4 6.3 2 8.5 0.2 2.3 2 0 0 2 2 2 0 CD20-like family EPL1 PF10513.9 CDJ51525.1 - 0.59 10.5 19.8 2.2 8.7 9.5 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like GWT1 PF06423.12 CDJ51525.1 - 0.71 10.0 2.4 26 4.9 0.6 2.2 2 0 0 2 2 2 0 GWT1 BSMAP PF12280.8 CDJ51525.1 - 0.74 10.0 15.8 5.3 7.2 0.5 2.2 2 0 0 2 2 2 0 Brain specific membrane anchored protein TERB2 PF15101.6 CDJ51525.1 - 0.88 9.6 28.3 2.8 7.9 3.7 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF572 PF04502.13 CDJ51525.1 - 0.99 9.0 16.8 1.6 8.3 16.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFB6 PF17110.5 CDJ51525.1 - 1.4 8.7 8.9 6.3 6.5 5.0 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF1644 PF07800.12 CDJ51525.1 - 1.9 8.5 15.7 1.3 9.0 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Med15 PF09606.10 CDJ51525.1 - 2.2 6.9 47.7 2.8 6.5 47.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4471 PF14740.6 CDJ51525.1 - 2.3 7.4 11.6 1.6 7.9 5.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Rpp20 PF12328.8 CDJ51525.1 - 2.5 8.1 14.0 5.7 6.9 6.9 2.2 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Connexin PF00029.19 CDJ51525.1 - 2.6 7.7 12.0 5.2 6.8 7.1 2.1 2 0 0 2 2 2 0 Connexin Topoisom_I_N PF02919.15 CDJ51525.1 - 3.1 7.3 10.6 5.2 6.5 0.2 2.1 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment FAM176 PF14851.6 CDJ51525.1 - 3.7 7.2 10.0 7.4 6.2 4.6 2.2 2 0 0 2 2 2 0 FAM176 family Maf1 PF09174.10 CDJ51525.1 - 3.7 7.7 10.7 4.2 7.5 4.3 2.3 2 0 0 2 2 2 0 Maf1 regulator COX6A PF02046.15 CDJ51525.1 - 4.4 7.8 13.6 12 6.4 0.2 2.6 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VIa Pap_E4 PF02711.14 CDJ51525.1 - 5.1 8.1 28.2 6.1 7.9 6.2 2.4 2 0 0 2 2 2 0 E4 protein EOS1 PF12326.8 CDJ51525.1 - 6.3 6.7 15.5 6.8 6.6 7.6 2.1 1 1 1 2 2 2 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ51525.1 - 6.9 5.5 21.8 2.9 6.7 0.9 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4518 PF15008.6 CDJ51525.1 - 7.6 5.6 20.1 3.4 6.8 10.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) Peroxin-13_N PF04088.13 CDJ51525.1 - 8.1 6.7 10.8 13 6.0 5.0 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region SAP PF02037.27 CDJ51526.1 - 2e-14 52.9 0.5 5.3e-14 51.6 0.1 1.8 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 CDJ51526.1 - 0.00031 20.4 0.0 0.00078 19.1 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain Ish1 PF10281.9 CDJ51526.1 - 0.014 15.7 0.1 3.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Tho1_MOS11_C PF18592.1 CDJ51526.1 - 0.16 11.8 5.5 0.078 12.8 2.6 2.0 1 1 1 2 2 2 0 Tho1/MOS11 C-terminal domain Sporozoite_P67 PF05642.11 CDJ51526.1 - 0.52 8.3 7.6 0.66 8.0 7.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tic110 PF16940.5 CDJ51526.1 - 0.52 8.7 9.9 0.73 8.2 9.9 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter Peptidase_S21 PF00716.17 CDJ51526.1 - 4.3 6.9 14.9 5.6 6.6 14.9 1.2 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Adaptin_N PF01602.20 CDJ51527.1 - 4e-60 203.9 6.2 4.3e-31 108.1 0.2 2.2 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 CDJ51527.1 - 4.3e-09 36.6 0.2 3.2e-07 30.5 0.1 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ51527.1 - 0.0011 19.3 0.9 0.0011 19.3 0.9 6.3 7 1 0 7 7 7 2 HEAT repeats FAM176 PF14851.6 CDJ51527.1 - 0.46 10.1 13.0 0.21 11.2 1.5 2.9 2 0 0 2 2 2 0 FAM176 family DUF572 PF04502.13 CDJ51527.1 - 0.74 9.4 26.3 0.14 11.8 4.7 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF572) DUF2052 PF09747.9 CDJ51527.1 - 0.96 9.5 26.9 0.16 12.0 7.1 2.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) HEAT PF02985.22 CDJ51527.1 - 2.6 8.6 18.0 8.7 6.9 0.0 6.5 7 0 0 7 7 7 0 HEAT repeat Connexin PF00029.19 CDJ51527.1 - 4.9 6.8 14.0 3.8 7.2 0.9 2.5 2 0 0 2 2 2 0 Connexin MAP17 PF15807.5 CDJ51527.1 - 8.9 6.6 14.6 0.64 10.3 0.8 2.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 XPG_I PF00867.18 CDJ51528.1 - 1.6e-28 98.8 0.0 3e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDJ51528.1 - 6.7e-13 49.0 0.0 1.5e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 CDJ51528.1 - 3.7e-06 27.5 0.0 1.1e-05 25.9 0.0 1.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF3231 PF11553.8 CDJ51528.1 - 0.0095 15.6 0.0 0.063 12.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3231) K_channel_TID PF07941.11 CDJ51528.1 - 4.1 7.9 12.0 0.3 11.6 6.6 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Tim54 PF11711.8 CDJ51530.1 - 0.0068 15.2 4.1 0.025 13.4 4.1 1.7 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Ribonuc_red_lgC PF02867.15 CDJ51530.1 - 0.086 11.4 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain DUF2722 PF10846.8 CDJ51530.1 - 0.14 11.1 27.9 0.03 13.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Ppx-GppA PF02541.16 CDJ51530.1 - 0.39 10.1 3.3 0.53 9.7 3.3 1.1 1 0 0 1 1 1 0 Ppx/GppA phosphatase family SLATT_1 PF18181.1 CDJ51530.1 - 0.43 10.5 12.5 0.046 13.6 6.3 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Peptidase_S49_N PF08496.10 CDJ51530.1 - 0.53 10.3 8.4 1.9 8.5 3.9 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal EphA2_TM PF14575.6 CDJ51530.1 - 0.53 11.2 5.7 1.4 9.8 0.5 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3506 PF12014.8 CDJ51530.1 - 0.71 9.9 3.6 7.9 6.5 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) PH_4 PF15404.6 CDJ51530.1 - 0.8 9.5 5.5 5.2 6.8 2.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain 2OG-FeII_Oxy_5 PF13759.6 CDJ51530.1 - 0.88 10.0 3.8 1.8 9.0 0.7 2.2 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Pex14_N PF04695.13 CDJ51530.1 - 1.2 9.8 20.7 2.5 8.7 12.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Exonuc_VII_L PF02601.15 CDJ51530.1 - 1.7 8.2 15.8 0.2 11.2 9.6 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4050 PF13259.6 CDJ51530.1 - 2.1 8.6 10.8 3.8 7.8 10.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) DUF4834 PF16118.5 CDJ51530.1 - 3.7 8.6 11.7 11 7.0 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RED_N PF07808.13 CDJ51530.1 - 5.1 6.6 14.1 9.4 5.7 6.8 2.3 2 0 0 2 2 2 0 RED-like protein N-terminal region FAM199X PF15814.5 CDJ51531.1 - 0.032 13.3 6.4 0.034 13.2 6.4 1.0 1 0 0 1 1 1 0 Protein family FAM199X Bac_luciferase PF00296.20 CDJ51531.1 - 0.038 13.4 13.7 0.039 13.4 13.7 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF2232 PF09991.9 CDJ51531.1 - 0.05 12.8 4.8 0.06 12.5 4.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) TFIIA PF03153.13 CDJ51531.1 - 0.1 12.6 16.3 0.1 12.6 16.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dehydrin PF00257.19 CDJ51531.1 - 0.66 10.5 6.1 0.71 10.4 6.1 1.1 1 0 0 1 1 1 0 Dehydrin R_equi_Vir PF05526.11 CDJ51531.1 - 2.3 8.0 12.1 3.1 7.6 12.1 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF726 PF05277.12 CDJ51531.1 - 3.6 6.4 9.3 3.7 6.4 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Tic110 PF16940.5 CDJ51531.1 - 4.2 5.7 12.8 4.5 5.7 12.8 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter RskA PF10099.9 CDJ51531.1 - 5.6 7.2 26.2 7.3 6.8 26.2 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Endonuc_Holl PF10107.9 CDJ51533.1 - 0.68 9.8 10.5 0.8 9.5 10.5 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Pex14_N PF04695.13 CDJ51533.1 - 1.1 9.9 16.8 1.5 9.5 16.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bud13 PF09736.9 CDJ51533.1 - 2.5 8.5 16.4 2.8 8.3 16.4 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex LCIB_C_CA PF18599.1 CDJ51533.1 - 8 5.7 9.8 8.9 5.5 9.8 1.0 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases eIF-3_zeta PF05091.12 CDJ51533.1 - 9.7 5.0 15.2 10 5.0 15.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AF-4 PF05110.13 CDJ51534.1 - 3.7e-05 22.1 53.5 4.3e-05 21.8 53.5 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Hamartin PF04388.12 CDJ51534.1 - 0.45 9.1 45.4 0.48 9.0 45.4 1.1 1 0 0 1 1 1 0 Hamartin protein PPP4R2 PF09184.11 CDJ51534.1 - 0.84 9.2 33.7 1.4 8.4 33.7 1.3 1 0 0 1 1 1 0 PPP4R2 PAT1 PF09770.9 CDJ51534.1 - 5.7 5.1 80.2 6.6 4.9 80.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2722 PF10846.8 CDJ51535.1 - 0.063 12.2 27.9 0.075 12.0 27.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ51535.1 - 0.14 12.1 16.6 0.16 11.9 16.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2464 PF10240.9 CDJ51535.1 - 0.27 10.8 10.8 0.33 10.5 10.8 1.0 1 0 0 1 1 1 0 Multivesicular body subunit 12 Med15 PF09606.10 CDJ51535.1 - 0.31 9.7 27.4 0.3 9.7 27.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ51535.1 - 0.37 10.4 37.8 0.43 10.1 37.8 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ51535.1 - 0.38 10.7 33.2 0.4 10.6 33.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ51535.1 - 0.43 10.0 13.6 0.45 9.9 13.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NARP1 PF12569.8 CDJ51535.1 - 0.44 9.4 9.8 0.44 9.4 9.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GNAT_acetyltr_2 PF13718.6 CDJ51535.1 - 0.48 9.8 8.4 0.54 9.6 8.4 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Pex14_N PF04695.13 CDJ51535.1 - 0.51 11.0 21.9 0.55 10.9 21.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HSP70 PF00012.20 CDJ51535.1 - 0.57 8.3 8.0 0.63 8.2 8.0 1.0 1 0 0 1 1 1 0 Hsp70 protein DDHD PF02862.17 CDJ51535.1 - 0.58 10.3 10.8 0.58 10.3 10.8 1.1 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.6 CDJ51535.1 - 0.7 10.1 11.8 0.81 9.9 11.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Tim54 PF11711.8 CDJ51535.1 - 0.71 8.6 12.4 0.76 8.5 12.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PA26 PF04636.13 CDJ51535.1 - 0.71 8.7 8.0 0.78 8.6 8.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Peptidase_S49_N PF08496.10 CDJ51535.1 - 0.75 9.8 10.3 0.87 9.6 10.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.12 CDJ51535.1 - 0.75 8.7 15.0 0.81 8.6 15.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RAB3GAP2_C PF14656.6 CDJ51535.1 - 0.85 7.8 13.3 1 7.5 13.3 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus CDC45 PF02724.14 CDJ51535.1 - 0.85 7.8 10.2 0.83 7.9 10.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Spem1 PF15670.5 CDJ51535.1 - 0.87 9.1 12.0 0.9 9.1 12.0 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 Presenilin PF01080.17 CDJ51535.1 - 0.94 8.2 15.1 0.92 8.2 15.1 1.0 1 0 0 1 1 1 0 Presenilin EPL1 PF10513.9 CDJ51535.1 - 0.98 9.8 14.4 1.1 9.7 14.4 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like XAP5 PF04921.14 CDJ51535.1 - 0.99 9.2 10.6 1.1 9.1 10.6 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF4571 PF15137.6 CDJ51535.1 - 1.1 8.8 3.1 1.2 8.7 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) Connexin PF00029.19 CDJ51535.1 - 1.2 8.9 8.4 1.3 8.8 8.4 1.1 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 CDJ51535.1 - 1.3 8.8 12.8 1.3 8.8 12.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATG22 PF11700.8 CDJ51535.1 - 1.3 7.6 6.9 1.6 7.3 6.9 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like SLC12 PF03522.15 CDJ51535.1 - 1.3 7.9 11.6 1.4 7.9 11.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CobT PF06213.12 CDJ51535.1 - 1.4 8.3 22.6 1.4 8.2 22.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Neur_chan_memb PF02932.16 CDJ51535.1 - 1.4 8.9 10.4 1.6 8.8 10.4 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF702 PF05142.12 CDJ51535.1 - 1.5 9.3 10.9 1.7 9.1 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF4770 PF15994.5 CDJ51535.1 - 1.6 8.9 15.6 1.8 8.8 15.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) TERB2 PF15101.6 CDJ51535.1 - 1.7 8.6 18.7 1.9 8.5 18.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ATP-synt_E PF05680.12 CDJ51535.1 - 1.8 9.0 11.6 2.1 8.7 11.6 1.1 1 0 0 1 1 1 0 ATP synthase E chain Gti1_Pac2 PF09729.9 CDJ51535.1 - 1.8 8.6 9.9 1.9 8.5 9.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family FHIPEP PF00771.20 CDJ51535.1 - 2 6.8 7.8 1.9 6.9 7.8 1.0 1 0 0 1 1 1 0 FHIPEP family FAM176 PF14851.6 CDJ51535.1 - 2 8.1 9.8 2.3 7.9 9.8 1.1 1 0 0 1 1 1 0 FAM176 family Rxt3 PF08642.10 CDJ51535.1 - 2.1 9.1 6.7 2.5 8.9 6.7 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 MAGE PF01454.19 CDJ51535.1 - 2.1 8.0 11.5 2.6 7.7 11.5 1.1 1 0 0 1 1 1 0 MAGE family MecA PF05389.12 CDJ51535.1 - 2.2 7.9 11.8 2.4 7.7 11.8 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF2126 PF09899.9 CDJ51535.1 - 2.3 6.2 8.4 2.3 6.2 8.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Band_3_cyto PF07565.13 CDJ51535.1 - 2.4 7.9 11.4 2.5 7.8 11.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain G0-G1_switch_2 PF15103.6 CDJ51535.1 - 2.5 8.6 8.7 3.1 8.3 8.7 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 AIF_C PF14721.6 CDJ51535.1 - 2.8 8.3 10.9 3.6 8.0 10.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term WASH-7_C PF14746.6 CDJ51535.1 - 2.8 7.6 10.9 3.2 7.4 10.9 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Maf1 PF09174.10 CDJ51535.1 - 3 8.0 9.8 3.6 7.7 9.8 1.1 1 0 0 1 1 1 0 Maf1 regulator Zip PF02535.22 CDJ51535.1 - 3.2 6.9 7.2 3.2 6.9 7.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 CDJ51535.1 - 3.3 7.7 10.3 3.6 7.5 10.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hydin_ADK PF17213.3 CDJ51535.1 - 3.3 7.9 10.8 4.8 7.4 10.8 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Ureide_permease PF07168.11 CDJ51535.1 - 3.3 6.4 5.8 3.6 6.3 5.8 1.0 1 0 0 1 1 1 0 Ureide permease YABBY PF04690.13 CDJ51535.1 - 3.5 8.2 8.5 3.8 8.1 8.5 1.1 1 0 0 1 1 1 0 YABBY protein DUF2828 PF11443.8 CDJ51535.1 - 3.6 5.6 10.7 3.9 5.4 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Kei1 PF08552.11 CDJ51535.1 - 3.6 7.4 8.2 3.8 7.3 8.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Folliculin PF11704.8 CDJ51535.1 - 3.6 7.4 11.7 4.2 7.2 11.7 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4175 PF13779.6 CDJ51535.1 - 3.8 5.3 30.7 3.8 5.3 30.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.9 CDJ51535.1 - 3.8 5.7 23.9 3.9 5.6 23.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.6 CDJ51535.1 - 4 6.7 15.0 4.2 6.6 15.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 CDJ51535.1 - 4.1 6.1 9.9 4.1 6.1 9.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Sec62 PF03839.16 CDJ51535.1 - 4.2 6.8 9.1 4.5 6.7 9.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 MDM10 PF12519.8 CDJ51535.1 - 4.2 6.1 11.0 4.4 6.0 11.0 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF775 PF05603.12 CDJ51535.1 - 4.3 6.8 13.5 5.2 6.5 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Membralin PF09746.9 CDJ51535.1 - 4.8 6.1 7.1 4.9 6.1 7.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein HemX PF04375.14 CDJ51535.1 - 5.3 6.2 25.5 5.7 6.1 25.5 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Peptidase_S64 PF08192.11 CDJ51535.1 - 5.6 5.3 12.4 6 5.2 12.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 CDJ51535.1 - 5.7 3.9 13.8 5.9 3.9 13.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer V_ATPase_I PF01496.19 CDJ51535.1 - 5.7 4.7 13.4 6 4.7 13.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Folate_carrier PF01770.18 CDJ51535.1 - 5.8 5.5 8.2 6.3 5.4 8.2 1.0 1 0 0 1 1 1 0 Reduced folate carrier Orf78 PF06024.12 CDJ51535.1 - 6 7.2 9.6 8.1 6.8 9.6 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Pannexin_like PF12534.8 CDJ51535.1 - 6.2 5.8 9.1 6.6 5.7 9.1 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Ctr PF04145.15 CDJ51535.1 - 6.2 7.4 7.8 6.7 7.3 7.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family CLN3 PF02487.17 CDJ51535.1 - 6.3 5.7 10.5 6.6 5.7 10.5 1.0 1 0 0 1 1 1 0 CLN3 protein TMEM51 PF15345.6 CDJ51535.1 - 6.6 6.5 14.1 7.1 6.4 14.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Lin-8 PF03353.15 CDJ51535.1 - 7.6 6.0 18.3 8.2 5.9 18.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist OATP PF03137.20 CDJ51535.1 - 7.7 4.7 9.6 7.8 4.6 9.6 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DcuA_DcuB PF03605.14 CDJ51535.1 - 8.3 5.2 7.7 9.7 5.0 7.7 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter PepSY_TM PF03929.16 CDJ51535.1 - 8.4 6.0 8.7 8.3 6.0 8.7 1.1 1 0 0 1 1 1 0 PepSY-associated TM region PIP5K PF01504.18 CDJ51535.1 - 8.7 5.5 11.4 9.7 5.3 11.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase MDM31_MDM32 PF08118.11 CDJ51535.1 - 9.1 4.8 9.8 10 4.6 9.8 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins EOS1 PF12326.8 CDJ51535.1 - 9.2 6.2 7.6 11 5.9 7.6 1.1 1 0 0 1 1 1 0 N-glycosylation protein Roughex PF06020.11 CDJ51535.1 - 9.4 5.2 21.9 13 4.8 21.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Paramyxo_ncap PF00973.19 CDJ51535.1 - 9.4 5.0 8.4 9.2 5.0 8.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Pex26 PF07163.12 CDJ51535.1 - 9.5 5.4 12.6 10 5.3 12.6 1.1 1 0 0 1 1 1 0 Pex26 protein CSG2 PF16965.5 CDJ51535.1 - 9.9 5.0 8.4 11 4.8 8.4 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator GNAT_acetyltr_2 PF13718.6 CDJ51536.1 - 1.7e-78 263.1 7.5 3e-53 180.6 0.0 3.7 3 1 2 5 5 5 2 GNAT acetyltransferase 2 PCMT PF01135.19 CDJ51536.1 - 9.3e-45 153.0 0.0 9.3e-45 153.0 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Helicase_RecD PF05127.14 CDJ51536.1 - 5.6e-39 133.8 5.0 2.3e-21 76.4 0.0 3.8 3 1 1 4 4 4 2 Helicase tRNA_bind_2 PF13725.6 CDJ51536.1 - 3.1e-35 122.0 0.2 5e-30 104.9 0.1 3.6 4 0 0 4 4 3 2 Possible tRNA binding domain Methyltransf_31 PF13847.6 CDJ51536.1 - 0.00095 19.0 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Acetyltransf_1 PF00583.25 CDJ51536.1 - 0.00098 19.3 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Methyltransf_23 PF13489.6 CDJ51536.1 - 0.0021 17.9 0.0 0.0093 15.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain LCD1 PF09798.9 CDJ51536.1 - 0.0094 14.5 0.1 0.033 12.7 0.1 1.7 1 1 0 1 1 1 1 DNA damage checkpoint protein Nop14 PF04147.12 CDJ51536.1 - 0.028 12.6 14.7 0.058 11.6 14.7 1.4 1 0 0 1 1 1 0 Nop14-like family Methyltransf_25 PF13649.6 CDJ51536.1 - 0.037 14.7 0.4 0.22 12.3 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Acetyltransf_7 PF13508.7 CDJ51536.1 - 0.064 13.7 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DDHD PF02862.17 CDJ51536.1 - 1.5 8.9 5.1 2 8.5 1.4 2.2 2 0 0 2 2 2 0 DDHD domain Spt20 PF12090.8 CDJ51536.1 - 1.5 8.4 23.1 0.45 10.1 8.1 2.7 2 0 0 2 2 2 0 Spt20 family PRP38_assoc PF12871.7 CDJ51536.1 - 2.5 8.8 12.7 4.7 7.9 12.7 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Stevor PF17410.2 CDJ51537.1 - 0.051 13.1 0.1 0.098 12.2 0.1 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SUIM_assoc PF16619.5 CDJ51538.1 - 7.5e-08 32.3 8.0 0.062 13.4 8.0 2.8 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Gly-zipper_OmpA PF13436.6 CDJ51538.1 - 0.012 15.4 7.2 0.012 15.4 7.2 4.9 3 1 1 4 4 2 0 Glycine-zipper domain CPSF100_C PF13299.6 CDJ51538.1 - 0.23 11.6 8.0 0.39 10.9 8.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 CDJ51538.1 - 0.48 10.5 7.0 0.79 9.8 7.0 1.3 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 CDJ51538.1 - 0.53 10.1 7.1 0.71 9.7 7.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 CDJ51538.1 - 0.61 10.0 28.6 1.1 9.1 28.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ51538.1 - 1.1 10.3 9.9 2.1 9.4 9.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 CDJ51538.1 - 1.3 9.0 6.4 2.2 8.3 6.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4228 PF14009.6 CDJ51538.1 - 1.5 9.2 8.4 34 4.8 7.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Hid1 PF12722.7 CDJ51538.1 - 5.6 5.0 10.6 8.3 4.4 10.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.12 CDJ51538.1 - 6.5 5.6 16.3 8.7 5.2 16.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIIBC-GUT_N PF03612.14 CDJ51538.1 - 7 6.4 7.7 11 5.7 7.7 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Baculo_PP31 PF05311.11 CDJ51538.1 - 9.3 5.6 10.6 14 5.1 10.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Chorein_N PF12624.7 CDJ51540.1 - 3.8e-19 68.9 0.0 3.8e-19 68.9 0.0 7.2 8 0 0 8 8 8 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CDJ51540.1 - 9.3e-10 38.7 0.0 6.2e-08 32.7 0.0 3.1 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 CDJ51540.1 - 1.5e-06 28.1 0.0 4.8e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CDJ51540.1 - 6.8e-06 25.7 0.0 0.00014 21.4 0.0 3.1 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 DUF2285 PF10074.9 CDJ51541.1 - 0.25 12.0 11.5 0.38 11.4 2.6 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) DUF3327 PF11806.8 CDJ51541.1 - 0.31 11.8 8.5 0.19 12.4 5.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3327) Allantoicase PF03561.15 CDJ51541.1 - 0.75 9.8 3.0 0.86 9.6 1.4 1.8 1 1 1 2 2 2 0 Allantoicase repeat DUF3720 PF12517.8 CDJ51541.1 - 1.5 9.8 13.4 0.13 13.2 6.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3720) DUF4407 PF14362.6 CDJ51541.1 - 4.3 6.6 10.9 5.6 6.2 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RAP1 PF07218.11 CDJ51541.1 - 5.2 5.2 5.3 5.7 5.1 5.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_60s PF00428.19 CDJ51541.1 - 7.7 7.2 8.9 0.55 10.9 3.2 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein DinB_2 PF12867.7 CDJ51541.1 - 7.9 7.0 10.5 13 6.3 2.2 2.2 1 1 0 2 2 2 0 DinB superfamily Kinesin PF00225.23 CDJ51542.1 - 3.3e-62 210.3 0.3 3.3e-62 210.3 0.3 1.8 1 1 1 2 2 2 1 Kinesin motor domain EIF4E-T PF10477.9 CDJ51542.1 - 0.023 13.5 9.2 0.027 13.3 9.2 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Androgen_recep PF02166.16 CDJ51542.1 - 0.049 12.5 12.3 0.085 11.7 12.3 1.3 1 0 0 1 1 1 0 Androgen receptor DUF4834 PF16118.5 CDJ51542.1 - 0.08 13.9 4.1 0.21 12.6 4.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF5349 PF17298.2 CDJ51542.1 - 0.2 11.4 6.7 0.32 10.7 6.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Spt20 PF12090.8 CDJ51542.1 - 0.27 10.8 21.6 0.15 11.7 19.3 1.6 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 CDJ51542.1 - 0.43 9.3 2.7 0.64 8.7 2.7 1.2 1 0 0 1 1 1 0 Presenilin Rpp20 PF12328.8 CDJ51542.1 - 0.46 10.5 6.5 1.1 9.3 6.5 1.6 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Mak10 PF04112.13 CDJ51542.1 - 4.4 6.8 5.8 7.1 6.1 5.3 1.5 1 1 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF2722 PF10846.8 CDJ51542.1 - 5.9 5.7 20.1 12 4.8 20.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ51543.1 - 3.1 8.2 9.4 12 6.3 3.8 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like SWIRM-assoc_2 PF16496.5 CDJ51543.1 - 3.8 6.3 11.8 6.1 5.6 11.8 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Spt20 PF12090.8 CDJ51544.1 - 0.0017 18.1 4.3 0.0017 18.1 4.3 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ51544.1 - 0.0085 15.1 2.0 0.0083 15.1 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Ribosomal_60s PF00428.19 CDJ51544.1 - 0.009 16.6 10.8 0.013 16.0 10.8 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein RAB3GAP2_N PF14655.6 CDJ51544.1 - 0.1 11.8 0.9 0.14 11.4 0.9 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3138 PF11336.8 CDJ51544.1 - 1.1 7.7 8.4 1.3 7.5 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) BAF1_ABF1 PF04684.13 CDJ51545.1 - 0.013 14.6 9.8 0.017 14.2 9.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ51545.1 - 0.034 14.2 26.6 0.036 14.1 26.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IHABP4_N PF16174.5 CDJ51545.1 - 0.04 14.5 17.9 0.056 14.0 17.9 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Ribosomal_60s PF00428.19 CDJ51545.1 - 0.29 11.7 10.5 0.67 10.6 10.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Velvet PF11754.8 CDJ51545.1 - 0.36 10.7 11.4 0.43 10.5 11.4 1.1 1 0 0 1 1 1 0 Velvet factor GREB1 PF15782.5 CDJ51545.1 - 0.51 7.4 12.1 0.58 7.2 12.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EPL1 PF10513.9 CDJ51545.1 - 1.1 9.6 10.3 1.3 9.4 10.3 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like SLC12 PF03522.15 CDJ51545.1 - 1.2 8.0 8.4 1.2 8.1 8.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Serinc PF03348.15 CDJ51545.1 - 1.9 7.3 3.8 2.4 7.0 3.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hydin_ADK PF17213.3 CDJ51545.1 - 3.3 7.9 15.7 4 7.7 15.7 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CD20 PF04103.15 CDJ51545.1 - 3.3 7.8 5.0 9.3 6.3 5.0 1.8 1 1 0 1 1 1 0 CD20-like family Presenilin PF01080.17 CDJ51545.1 - 5.4 5.7 14.9 6.2 5.5 14.9 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ51545.1 - 5.8 5.1 20.9 6.3 4.9 20.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 CDJ51545.1 - 6.5 6.5 9.4 7 6.4 9.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.12 CDJ51545.1 - 7.2 5.5 13.6 8 5.3 13.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EFP_N PF08207.12 CDJ51546.1 - 1.6e-05 24.8 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain ATP_bind_3 PF01171.20 CDJ51547.1 - 2.3e-06 27.5 0.0 2.3e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 PP-loop family Trp_oprn_chp PF09534.10 CDJ51547.1 - 0.0011 18.8 13.4 0.0011 18.8 13.4 3.0 2 1 1 3 3 3 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2298 PF10060.9 CDJ51547.1 - 1.7 7.3 5.8 2.7 6.6 5.8 1.3 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) SpoIIP PF07454.11 CDJ51547.1 - 2.5 7.5 11.1 0.26 10.7 4.4 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) FHIPEP PF00771.20 CDJ51547.1 - 3.3 6.1 13.3 0.12 10.8 6.8 1.7 2 0 0 2 2 2 0 FHIPEP family DUF2722 PF10846.8 CDJ51548.1 - 0.00046 19.3 0.8 0.00046 19.3 0.8 14.7 10 2 2 12 12 12 6 Protein of unknown function (DUF2722) HAUS6_N PF14661.6 CDJ51550.1 - 0.12 11.9 11.8 0.17 11.5 11.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Borrelia_P83 PF05262.11 CDJ51550.1 - 0.26 9.7 11.3 0.25 9.8 11.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIF_alpha PF05793.12 CDJ51550.1 - 0.41 9.2 13.2 0.46 9.0 13.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 CDJ51550.1 - 0.42 8.8 7.3 0.39 8.9 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MMR1 PF08505.10 CDJ51550.1 - 0.54 10.5 15.9 0.61 10.3 15.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein V_ATPase_I PF01496.19 CDJ51550.1 - 0.87 7.4 6.5 0.85 7.5 6.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0560 PF10577.9 CDJ51550.1 - 0.92 7.9 20.7 1.2 7.5 20.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Herpes_UL6 PF01763.16 CDJ51550.1 - 1.5 7.3 7.4 1.8 7.0 7.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like MCU PF04678.13 CDJ51550.1 - 1.5 8.9 9.9 2.8 8.0 9.9 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Spc24 PF08286.11 CDJ51550.1 - 1.7 8.9 9.2 2.5 8.4 9.2 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 SpoIIP PF07454.11 CDJ51550.1 - 1.9 7.8 9.1 2.1 7.8 9.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Utp14 PF04615.13 CDJ51550.1 - 3 6.3 24.4 3.5 6.1 24.4 1.0 1 0 0 1 1 1 0 Utp14 protein SLC12 PF03522.15 CDJ51550.1 - 5.3 6.0 9.9 5.2 6.0 9.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 CDJ51550.1 - 6.1 5.5 7.5 5.8 5.6 7.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter USP8_interact PF08941.10 CDJ51550.1 - 7.9 6.2 10.8 9.9 5.9 10.8 1.2 1 0 0 1 1 1 0 USP8 interacting MPM1 PF17234.2 CDJ51550.1 - 8.7 6.6 13.0 11 6.2 13.0 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Sad1_UNC PF07738.13 CDJ51553.1 - 4.2e-14 52.7 0.0 1.2e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RVP_2 PF08284.11 CDJ51554.1 - 1.5e-07 31.2 0.0 2.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ51554.1 - 1.9e-06 28.4 0.0 4.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ51554.1 - 2.3e-05 24.9 0.1 8.9e-05 23.0 0.0 2.1 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ51554.1 - 0.071 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Spt20 PF12090.8 CDJ51555.1 - 0.018 14.7 13.3 0.018 14.7 13.3 2.5 2 1 0 2 2 2 0 Spt20 family RskA PF10099.9 CDJ51557.1 - 0.0094 16.3 4.9 0.0094 16.3 4.9 3.4 2 1 1 3 3 3 1 Anti-sigma-K factor rskA EPL1 PF10513.9 CDJ51557.1 - 0.055 13.8 1.6 2.6 8.4 0.7 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF2722 PF10846.8 CDJ51557.1 - 0.94 8.4 17.9 1.6 7.6 7.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ51557.1 - 3.3 7.6 34.3 2.2 8.2 5.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 CDJ51558.1 - 0.0071 16.4 20.6 0.0071 16.4 20.6 3.1 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ51558.1 - 0.23 11.3 26.1 0.027 14.4 9.5 2.5 2 1 0 2 2 2 0 SPX domain ThrE PF06738.12 CDJ51558.1 - 0.24 10.7 0.1 0.24 10.7 0.1 2.5 2 0 0 2 2 2 0 Putative threonine/serine exporter Band_3_cyto PF07565.13 CDJ51558.1 - 0.63 9.8 8.0 0.62 9.8 0.6 2.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PPL5 PF18168.1 CDJ51559.1 - 0.24 10.7 18.1 0.071 12.4 13.5 1.9 2 0 0 2 2 2 0 Prim-pol family 5 GAGA_bind PF06217.12 CDJ51559.1 - 0.51 10.6 24.2 0.65 10.2 24.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1168 PF06658.12 CDJ51559.1 - 3.7 7.4 31.7 0.14 11.9 21.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) BPL_N PF09825.9 CDJ51559.1 - 4.4 6.3 18.4 6.1 5.8 18.4 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal CobT PF06213.12 CDJ51559.1 - 5.6 6.3 36.6 0.52 9.6 28.0 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SYF2 PF08231.12 CDJ51559.1 - 6.6 7.1 24.2 4.3 7.7 19.3 2.0 2 0 0 2 2 2 0 SYF2 splicing factor DUF2877 PF11392.8 CDJ51559.1 - 6.7 7.5 11.3 34 5.2 9.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Pyr_redox_2 PF07992.14 CDJ51560.1 - 3.9e-15 55.9 0.2 4.9e-11 42.4 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDJ51560.1 - 3.7e-09 37.0 2.2 8.7e-09 35.8 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CNDH2_C PF16858.5 CDJ51561.1 - 2.4e-08 34.2 0.0 2.4e-08 34.2 0.0 7.6 2 2 3 6 6 6 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF1645 PF07816.11 CDJ51561.1 - 0.015 15.9 2.5 0.015 15.9 2.5 9.0 6 3 2 8 8 8 0 Protein of unknown function (DUF1645) DUF4179 PF13786.6 CDJ51561.1 - 0.098 13.1 10.0 11 6.5 0.0 5.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4179) SUIM_assoc PF16619.5 CDJ51562.1 - 0.0067 16.5 3.3 0.0067 16.5 3.3 2.4 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF755 PF05501.11 CDJ51564.1 - 0.0002 21.6 31.9 0.0002 21.6 31.9 5.6 5 1 1 6 6 6 1 Domain of unknown function (DUF755) TFB6 PF17110.5 CDJ51564.1 - 0.013 15.3 1.4 0.013 15.3 1.4 4.2 3 1 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH SR-25 PF10500.9 CDJ51564.1 - 0.25 10.9 70.1 0.036 13.7 22.6 5.4 5 0 0 5 5 5 0 Nuclear RNA-splicing-associated protein O-antigen_lig PF13425.6 CDJ51565.1 - 1 8.1 2.7 1.3 7.7 2.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein tRNA-synt_2d PF01409.20 CDJ51566.1 - 5.2e-07 29.4 0.0 0.00011 21.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Peptidase_M16 PF00675.20 CDJ51566.1 - 1.1e-06 28.7 0.0 1.1e-06 28.7 0.0 6.8 9 0 0 9 9 9 1 Insulinase (Peptidase family M16) DUF4490 PF14892.6 CDJ51567.1 - 5.9e-07 29.5 0.0 8.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) UCR_14kD PF02271.16 CDJ51568.1 - 0.047 13.6 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit NPR3 PF03666.13 CDJ51570.1 - 0.14 11.0 23.4 0.15 10.8 23.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 V_ATPase_I PF01496.19 CDJ51570.1 - 0.26 9.2 25.9 0.28 9.1 25.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDRGK PF09756.9 CDJ51570.1 - 0.45 10.1 37.7 0.55 9.8 37.7 1.1 1 0 0 1 1 1 0 DDRGK domain DUF2370 PF10176.9 CDJ51570.1 - 0.49 10.0 12.3 0.59 9.7 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Tim54 PF11711.8 CDJ51570.1 - 0.83 8.4 21.8 1.2 7.9 21.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM60A PF15396.6 CDJ51570.1 - 0.97 9.4 23.9 1.2 9.2 23.9 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF913 PF06025.12 CDJ51570.1 - 1 8.2 17.2 1.2 8.0 17.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CDJ51570.1 - 1 9.1 30.5 1.2 8.9 30.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ51570.1 - 1.1 8.0 22.6 1.3 7.8 22.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CSG2 PF16965.5 CDJ51570.1 - 1.2 8.0 14.9 1.4 7.8 14.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2052 PF09747.9 CDJ51570.1 - 1.5 8.9 28.3 1.7 8.7 28.3 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2828 PF11443.8 CDJ51570.1 - 1.6 6.7 27.3 1.9 6.5 27.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3295 PF11702.8 CDJ51570.1 - 1.6 8.0 25.7 1.7 7.9 25.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) eIF-3_zeta PF05091.12 CDJ51570.1 - 2 7.3 35.5 2.9 6.7 35.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DNA_pol_delta_4 PF04081.13 CDJ51570.1 - 2.6 8.4 20.9 3.3 8.1 20.9 1.2 1 0 0 1 1 1 0 DNA polymerase delta, subunit 4 DUF4220 PF13968.6 CDJ51570.1 - 2.9 7.2 6.5 3.5 6.9 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF4366 PF14283.6 CDJ51570.1 - 3 7.9 14.0 4 7.5 14.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 CDJ51570.1 - 4.4 6.0 36.6 5.1 5.8 36.6 1.0 1 0 0 1 1 1 0 Presenilin Cdh1_DBD_1 PF18196.1 CDJ51570.1 - 4.5 7.6 17.0 5.7 7.3 17.0 1.1 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 SKA1 PF07160.12 CDJ51570.1 - 6.3 6.6 30.9 7.7 6.3 30.9 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Rtf2 PF04641.12 CDJ51570.1 - 6.7 6.0 26.1 8 5.7 26.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger MTBP_C PF14920.6 CDJ51570.1 - 7.4 6.2 23.1 8.6 6.0 23.1 1.0 1 0 0 1 1 1 0 MDM2-binding DUF4569 PF15133.6 CDJ51570.1 - 7.5 6.2 32.2 8.7 6.0 32.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) CDC45 PF02724.14 CDJ51570.1 - 8 4.6 27.2 9.4 4.4 27.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 CDJ51570.1 - 8.5 5.7 21.0 10 5.4 21.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Hid1 PF12722.7 CDJ51570.1 - 9.1 4.3 28.4 10 4.1 28.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CLN3 PF02487.17 CDJ51570.1 - 9.6 5.1 22.6 11 4.9 22.6 1.1 1 0 0 1 1 1 0 CLN3 protein MFAP1 PF06991.11 CDJ51571.1 - 5.9e-06 26.3 25.8 5.9e-06 26.3 25.8 2.3 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing PAT1 PF09770.9 CDJ51571.1 - 1.2 7.4 28.9 1.3 7.2 28.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOBP PF15279.6 CDJ51571.1 - 1.6 9.3 13.1 2.2 8.8 13.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CDC27 PF09507.10 CDJ51571.1 - 4.1 6.7 33.4 4.6 6.5 33.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 CDJ51571.1 - 4.7 5.4 27.8 6.5 4.9 27.8 1.3 1 0 0 1 1 1 0 CDC45-like protein SMYLE_N PF18615.1 CDJ51572.1 - 1.5 8.3 25.8 1.6 8.2 25.8 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain CCSAP PF15748.5 CDJ51572.1 - 1.9 8.6 45.1 2.2 8.4 45.1 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF3446 PF11928.8 CDJ51572.1 - 4.5 7.6 15.6 0.072 13.4 7.6 2.1 2 1 0 2 2 2 0 Early growth response N-terminal domain DUF966 PF06136.13 CDJ51572.1 - 5.6 6.6 31.6 6.7 6.3 31.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF572 PF04502.13 CDJ51572.1 - 7.7 6.0 32.3 9.2 5.8 32.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FF PF01846.19 CDJ51573.1 - 1.6e-17 63.4 1.1 3.7e-11 43.0 0.0 4.3 4 0 0 4 4 4 2 FF domain WW PF00397.26 CDJ51573.1 - 8.6e-16 57.7 10.3 1.3e-09 38.0 2.3 2.7 2 0 0 2 2 2 2 WW domain Trypan_PARP PF05887.11 CDJ51573.1 - 0.083 12.9 5.6 0.15 12.1 5.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SUIM_assoc PF16619.5 CDJ51574.1 - 0.047 13.8 1.3 0.047 13.8 1.3 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4633 PF15464.6 CDJ51574.1 - 8.1 6.6 9.9 2.4 8.4 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4633) RskA PF10099.9 CDJ51575.1 - 1.5e-09 38.4 40.2 6.1e-09 36.4 10.9 6.5 2 2 3 5 5 5 2 Anti-sigma-K factor rskA DAG_kinase_N PF14513.6 CDJ51575.1 - 0.00051 20.3 18.2 0.00051 20.3 18.2 4.2 3 1 1 4 4 4 1 Diacylglycerol kinase N-terminus SAGA-Tad1 PF12767.7 CDJ51575.1 - 0.0027 17.5 10.7 0.0027 17.5 10.7 3.3 2 1 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit SARAF PF06682.12 CDJ51575.1 - 0.44 10.2 66.1 0.26 10.9 14.3 3.7 2 1 2 4 4 4 0 SOCE-associated regulatory factor of calcium homoeostasis TCP PF03634.13 CDJ51575.1 - 1.5 9.3 65.8 0.099 13.2 13.1 4.4 4 0 0 4 4 4 0 TCP family transcription factor Presenilin PF01080.17 CDJ51575.1 - 3.8 6.2 92.7 0.0087 14.9 21.7 3.7 4 0 0 4 4 4 0 Presenilin DUF572 PF04502.13 CDJ51576.1 - 0.2 11.3 24.9 0.23 11.1 24.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) PA26 PF04636.13 CDJ51576.1 - 0.45 9.4 15.7 0.53 9.2 15.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 CDJ51576.1 - 0.82 8.4 28.6 1 8.0 28.6 1.1 1 0 0 1 1 1 0 Presenilin GvpL_GvpF PF06386.11 CDJ51576.1 - 0.96 9.3 11.2 1.2 9.1 11.2 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Dsh_C PF12316.8 CDJ51576.1 - 1.1 9.6 30.9 1.4 9.3 30.9 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CDC45 PF02724.14 CDJ51576.1 - 1.5 7.1 19.3 1.8 6.8 19.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Tmemb_cc2 PF10267.9 CDJ51576.1 - 1.8 7.6 25.2 2.3 7.3 25.2 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CCSAP PF15748.5 CDJ51576.1 - 3.8 7.6 31.9 5.2 7.2 31.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SprA-related PF12118.8 CDJ51576.1 - 4.9 6.2 35.4 6.2 5.8 35.4 1.1 1 0 0 1 1 1 0 SprA-related family DUF4175 PF13779.6 CDJ51576.1 - 5.7 4.7 32.3 6.5 4.5 32.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Phage_GPO PF05929.11 CDJ51576.1 - 5.9 6.4 15.1 6.7 6.2 15.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase MCU PF04678.13 CDJ51576.1 - 6.2 6.9 9.0 8.1 6.5 9.0 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF853 PF05872.12 CDJ51576.1 - 6.9 5.1 13.0 7.8 5.0 13.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Dicty_REP PF05086.12 CDJ51576.1 - 8 4.3 18.2 8.5 4.2 18.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4407 PF14362.6 CDJ51576.1 - 8.5 5.6 17.6 13 5.0 17.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MAJIN PF15077.6 CDJ51576.1 - 9.8 5.9 20.9 11 5.7 20.9 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein eIF-3_zeta PF05091.12 CDJ51576.1 - 9.8 5.0 23.2 13 4.6 23.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_M16_M PF16187.5 CDJ51577.1 - 7.1e-27 94.4 12.1 1.8e-25 89.8 10.8 3.4 2 1 0 2 2 2 1 Middle or third domain of peptidase_M16 RskA PF10099.9 CDJ51577.1 - 0.44 10.8 36.8 0.37 11.1 3.3 4.7 2 2 1 3 3 3 0 Anti-sigma-K factor rskA Zip PF02535.22 CDJ51578.1 - 6e-13 48.7 0.1 6e-13 48.7 0.1 3.4 2 2 2 4 4 4 1 ZIP Zinc transporter LMBR1 PF04791.16 CDJ51578.1 - 0.2 10.5 0.1 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein MTABC_N PF16185.5 CDJ51578.1 - 4.8 6.6 5.8 12 5.3 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region PIP5K PF01504.18 CDJ51578.1 - 6.3 5.9 7.7 3.1 6.9 3.7 2.0 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase PEX11 PF05648.14 CDJ51578.1 - 8.1 5.8 7.5 43 3.5 0.0 3.0 3 1 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) Sensor PF13796.6 CDJ51579.1 - 0.036 14.1 0.7 0.036 14.1 0.7 2.2 2 0 0 2 2 2 0 Putative sensor DUF3446 PF11928.8 CDJ51579.1 - 0.27 11.6 7.0 0.45 10.9 7.0 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain Apq12 PF12716.7 CDJ51579.1 - 3.5 7.7 8.2 0.16 12.0 0.7 2.2 2 1 0 2 2 2 0 Nuclear pore assembly and biogenesis Macoilin PF09726.9 CDJ51580.1 - 6.5 5.2 33.9 8.3 4.8 33.9 1.0 1 0 0 1 1 1 0 Macoilin family DUF2722 PF10846.8 CDJ51581.1 - 0.0015 17.6 4.6 0.0015 17.6 4.6 3.0 3 1 1 4 4 4 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ51581.1 - 0.0073 15.9 13.5 0.0073 15.9 13.5 2.8 3 0 0 3 3 3 2 Spt20 family TFIIA PF03153.13 CDJ51581.1 - 0.0095 16.0 9.7 0.0095 16.0 9.7 2.7 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 CDJ51581.1 - 0.28 10.8 3.9 0.1 12.3 0.6 2.0 2 0 0 2 2 2 0 FAM176 family DUF4127 PF13552.6 CDJ51581.1 - 0.46 9.0 5.4 0.16 10.5 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4127) DUF3464 PF11947.8 CDJ51581.1 - 0.92 9.3 4.5 0.7 9.6 0.6 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 RR_TM4-6 PF06459.12 CDJ51581.1 - 1.6 8.5 8.9 0.21 11.4 2.9 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ51581.1 - 4.9 7.1 10.1 3 7.8 0.5 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 CDJ51581.1 - 7.3 6.3 5.7 6.5 6.4 1.7 2.1 2 0 0 2 2 2 0 Connexin DUF572 PF04502.13 CDJ51581.1 - 9.3 5.8 12.0 1.3 8.6 1.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF3246 PF11596.8 CDJ51582.1 - 0.0025 17.3 2.1 0.003 17.0 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) SAP130_C PF16014.5 CDJ51582.1 - 0.029 13.5 4.2 0.041 13.0 4.2 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Astro_capsid_p PF12226.8 CDJ51582.1 - 0.55 9.3 3.7 0.86 8.7 3.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Tic110 PF16940.5 CDJ51582.1 - 2.9 6.2 9.2 3.8 5.9 9.2 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Spt20 PF12090.8 CDJ51583.1 - 0.00064 19.4 27.1 0.00064 19.4 27.1 3.5 2 1 2 4 4 3 1 Spt20 family CNDH2_M PF16869.5 CDJ51583.1 - 0.003 18.2 3.6 0.003 18.2 3.6 3.5 2 1 1 3 3 2 1 PF16858 SR-25 PF10500.9 CDJ51583.1 - 0.028 14.1 42.1 0.66 9.5 8.5 2.9 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Suf PF05843.14 CDJ51583.1 - 0.43 10.5 26.5 1 9.3 9.8 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) O-antigen_lig PF13425.6 CDJ51583.1 - 0.69 8.6 6.9 0.41 9.4 1.0 2.0 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Presenilin PF01080.17 CDJ51583.1 - 0.75 8.5 36.3 1.5 7.5 17.1 2.4 2 0 0 2 2 2 0 Presenilin TFIIA PF03153.13 CDJ51583.1 - 1.1 9.1 66.5 0.21 11.6 29.3 2.3 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 CDJ51583.1 - 1.5 7.2 8.7 0.41 9.0 2.6 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 FTZ PF03867.14 CDJ51583.1 - 1.7 8.1 21.1 2.7 7.5 7.5 2.5 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region CLN3 PF02487.17 CDJ51583.1 - 2.6 7.0 17.0 0.27 10.2 5.6 2.5 3 0 0 3 3 3 0 CLN3 protein SpoIIP PF07454.11 CDJ51583.1 - 2.8 7.3 25.5 0.43 10.0 9.7 2.5 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) MPM1 PF17234.2 CDJ51583.1 - 7.4 6.8 32.0 0.83 9.9 11.2 3.1 3 0 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 DSHCT PF08148.12 CDJ51585.1 - 9.8e-26 90.4 5.9 9.8e-26 90.4 5.9 1.9 2 1 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 CDJ51585.1 - 1.4e-21 77.6 0.0 1.4e-21 77.6 0.0 3.3 2 2 1 3 3 2 2 rRNA-processing arch domain CobT PF06213.12 CDJ51585.1 - 0.0006 19.3 9.7 0.00095 18.6 9.7 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 CDJ51585.1 - 0.0052 15.8 1.1 0.01 14.8 1.1 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DDHD PF02862.17 CDJ51585.1 - 0.0092 16.2 0.6 0.013 15.7 0.6 1.3 1 0 0 1 1 1 1 DDHD domain Presenilin PF01080.17 CDJ51585.1 - 0.029 13.1 1.5 0.037 12.8 1.5 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ51585.1 - 0.035 13.1 5.8 0.048 12.6 5.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NYAP_N PF15439.6 CDJ51585.1 - 0.09 12.0 1.4 0.12 11.5 1.4 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter PTPRCAP PF15713.5 CDJ51585.1 - 0.12 12.7 9.2 0.27 11.5 9.2 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Connexin PF00029.19 CDJ51585.1 - 0.12 12.1 0.3 0.17 11.6 0.3 1.2 1 0 0 1 1 1 0 Connexin Spt20 PF12090.8 CDJ51585.1 - 0.15 11.6 18.2 0.29 10.7 18.2 1.4 1 0 0 1 1 1 0 Spt20 family FAM91_C PF14648.6 CDJ51585.1 - 0.18 10.6 0.4 0.25 10.1 0.4 1.1 1 0 0 1 1 1 0 FAM91 C-terminus DUF2828 PF11443.8 CDJ51585.1 - 0.2 9.7 4.2 0.32 9.0 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1980 PF09323.10 CDJ51585.1 - 0.21 11.5 0.9 0.32 10.9 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Peptidase_S15 PF02129.18 CDJ51585.1 - 1 8.9 6.2 1.8 8.1 6.2 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) V_ATPase_I PF01496.19 CDJ51585.1 - 5.2 4.9 6.9 1.9 6.3 4.1 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ51585.1 - 5.5 6.9 21.4 0.42 10.6 16.4 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ51588.1 - 4.5e-05 23.6 0.7 0.038 13.9 0.0 2.2 2 0 0 2 2 2 2 SPX domain DUF755 PF05501.11 CDJ51588.1 - 0.00099 19.4 9.8 0.00099 19.4 9.8 3.3 3 0 0 3 3 2 1 Domain of unknown function (DUF755) DUF4667 PF15700.5 CDJ51588.1 - 0.0082 16.3 13.5 0.16 12.0 5.7 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4667) PRKG1_interact PF15898.5 CDJ51588.1 - 0.4 11.6 14.2 1.5 9.7 1.4 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain YrhC PF14143.6 CDJ51588.1 - 1.1 9.4 5.2 1.2 9.3 0.0 3.2 3 0 0 3 3 3 0 YrhC-like protein Vir_act_alpha_C PF10400.9 CDJ51588.1 - 3 8.6 11.1 0.37 11.5 3.1 2.3 2 0 0 2 2 2 0 Virulence activator alpha C-term TFIIA PF03153.13 CDJ51588.1 - 4.1 7.3 35.1 5.4 6.9 12.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ51588.1 - 4.3 6.9 30.7 6.1 6.4 12.3 2.1 2 0 0 2 2 2 0 Spt20 family Rpp20 PF12328.8 CDJ51588.1 - 4.7 7.2 7.8 0.43 10.5 0.7 2.0 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P MCU PF04678.13 CDJ51588.1 - 5.4 7.1 10.1 13 5.9 1.7 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter SelK_SelG PF10961.8 CDJ51588.1 - 5.5 7.7 0.0 5.5 7.7 0.0 4.4 5 0 0 5 5 5 0 Selenoprotein SelK_SelG RskA PF10099.9 CDJ51589.1 - 0.0004 20.7 17.5 0.0004 20.7 17.5 11.8 5 3 4 10 10 10 2 Anti-sigma-K factor rskA Spc24 PF08286.11 CDJ51589.1 - 0.0054 17.0 1.7 0.0054 17.0 1.7 6.3 5 1 1 6 6 6 1 Spc24 subunit of Ndc80 AAA_23 PF13476.6 CDJ51589.1 - 0.0054 17.3 0.0 0.0054 17.3 0.0 5.7 2 1 1 4 4 4 1 AAA domain SMC_N PF02463.19 CDJ51589.1 - 0.012 15.1 2.8 0.012 15.1 0.0 2.2 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 CDJ51589.1 - 1.8 9.1 0.0 1.8 9.1 0.0 4.3 3 1 0 3 3 3 0 ABC transporter Activator_LAG-3 PF11498.8 CDJ51590.1 - 0.0033 16.5 23.5 0.0033 16.5 23.5 3.8 2 1 1 3 3 3 1 Transcriptional activator LAG-3 RskA PF10099.9 CDJ51590.1 - 0.0079 16.5 22.4 0.0079 16.5 22.4 6.4 2 2 3 5 5 5 2 Anti-sigma-K factor rskA RskA PF10099.9 CDJ51591.1 - 0.0031 17.8 18.7 0.0031 17.8 18.7 10.8 4 2 3 8 8 8 3 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ51592.1 - 0.024 14.2 16.1 0.027 14.1 16.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TAF4 PF05236.14 CDJ51592.1 - 0.088 12.5 22.5 0.1 12.3 22.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family BSMAP PF12280.8 CDJ51592.1 - 0.54 10.4 6.9 0.59 10.3 6.9 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein Eapp_C PF10238.9 CDJ51592.1 - 0.75 9.9 12.2 0.77 9.8 12.2 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein XAP5 PF04921.14 CDJ51592.1 - 0.8 9.5 18.8 1 9.1 18.8 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator RNA_pol_Rpc4 PF05132.14 CDJ51592.1 - 0.97 9.9 13.6 1.1 9.7 13.6 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIP PF07454.11 CDJ51592.1 - 1.5 8.2 15.8 1.6 8.1 15.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Rxt3 PF08642.10 CDJ51592.1 - 1.7 9.5 6.1 1.8 9.3 6.1 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 EIIBC-GUT_N PF03612.14 CDJ51592.1 - 1.7 8.3 11.1 1.9 8.2 11.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Coilin_N PF15862.5 CDJ51592.1 - 1.7 8.4 18.3 2 8.2 18.3 1.2 1 0 0 1 1 1 0 Coilin N-terminus Tim54 PF11711.8 CDJ51592.1 - 1.8 7.3 17.5 2 7.1 17.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 CDJ51592.1 - 1.9 8.6 14.5 2 8.6 14.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SDA1 PF05285.12 CDJ51592.1 - 1.9 7.8 29.5 2.2 7.6 29.5 1.0 1 0 0 1 1 1 0 SDA1 Rtf2 PF04641.12 CDJ51592.1 - 2.6 7.3 18.6 3.1 7.1 18.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2722 PF10846.8 CDJ51592.1 - 2.8 6.8 14.3 2.7 6.8 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med19 PF10278.9 CDJ51592.1 - 2.9 7.8 19.7 3.3 7.6 19.7 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RPN2_C PF18004.1 CDJ51592.1 - 2.9 7.8 23.7 3.3 7.6 23.7 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Connexin PF00029.19 CDJ51592.1 - 3 7.5 14.6 3 7.5 14.6 1.1 1 0 0 1 1 1 0 Connexin Sec62 PF03839.16 CDJ51592.1 - 3 7.3 12.7 3.1 7.3 12.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Folate_carrier PF01770.18 CDJ51592.1 - 3.3 6.4 7.7 3.7 6.2 7.7 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF2052 PF09747.9 CDJ51592.1 - 3.3 7.8 25.2 3.4 7.8 25.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3405 PF11885.8 CDJ51592.1 - 3.7 6.0 10.4 3.9 6.0 10.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Vfa1 PF08432.10 CDJ51592.1 - 3.8 7.8 23.7 4.3 7.6 23.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3464 PF11947.8 CDJ51592.1 - 3.9 7.2 13.2 4.1 7.1 13.2 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SRRM_C PF15230.6 CDJ51592.1 - 3.9 8.1 16.4 19 5.9 16.4 2.3 1 1 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus AIF_C PF14721.6 CDJ51592.1 - 3.9 7.8 10.7 4.9 7.5 10.7 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term HSP90 PF00183.18 CDJ51592.1 - 4.4 6.1 23.0 4.5 6.0 23.0 1.0 1 0 0 1 1 1 0 Hsp90 protein GNAT_acetyltr_2 PF13718.6 CDJ51592.1 - 4.6 6.6 9.8 5 6.5 9.8 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF3438 PF11920.8 CDJ51592.1 - 4.8 6.4 7.2 5.2 6.2 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) ALMT PF11744.8 CDJ51592.1 - 4.8 5.9 10.3 5 5.8 10.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter ORC_WH_C PF18137.1 CDJ51592.1 - 5 7.2 17.6 5.8 7.0 17.6 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DDHD PF02862.17 CDJ51592.1 - 5.2 7.2 10.1 5.1 7.2 10.1 1.1 1 0 0 1 1 1 0 DDHD domain Afi1 PF07792.12 CDJ51592.1 - 5.3 7.5 14.1 6.4 7.3 14.1 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SspB PF04386.13 CDJ51592.1 - 5.7 6.8 15.6 7 6.5 15.6 1.1 1 0 0 1 1 1 0 Stringent starvation protein B TMEM214 PF10151.9 CDJ51592.1 - 6.2 5.2 14.2 6.3 5.1 14.2 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator TFB6 PF17110.5 CDJ51592.1 - 6.3 6.5 12.1 6.7 6.4 12.1 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RR_TM4-6 PF06459.12 CDJ51592.1 - 6.3 6.5 24.2 7.1 6.4 24.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paramyxo_ncap PF00973.19 CDJ51592.1 - 6.4 5.6 9.7 6.1 5.6 9.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RNA_polI_A34 PF08208.11 CDJ51592.1 - 6.6 6.8 31.4 7.1 6.7 31.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TRAP_alpha PF03896.16 CDJ51592.1 - 7.2 5.7 15.8 8.2 5.5 15.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Usp PF00582.26 CDJ51592.1 - 7.2 7.1 10.3 7.9 7.0 10.3 1.2 1 0 0 1 1 1 0 Universal stress protein family SLC12 PF03522.15 CDJ51592.1 - 7.3 5.5 12.0 7.6 5.4 12.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF2828 PF11443.8 CDJ51592.1 - 7.6 4.5 14.1 7.3 4.5 14.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MCM_bind PF09739.9 CDJ51592.1 - 7.9 4.8 14.7 8.1 4.8 14.7 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor YABBY PF04690.13 CDJ51592.1 - 8.2 7.0 9.1 9.3 6.8 9.1 1.1 1 0 0 1 1 1 0 YABBY protein TFIIF_alpha PF05793.12 CDJ51592.1 - 8.5 4.8 33.4 8.7 4.8 33.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Peptidase_U57 PF05582.12 CDJ51592.1 - 8.6 5.5 9.5 8.8 5.5 9.5 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Paf1 PF03985.13 CDJ51592.1 - 9 5.2 30.0 9.8 5.1 30.0 1.0 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 CDJ51592.1 - 9.2 4.9 14.5 10 4.8 14.5 1.0 1 0 0 1 1 1 0 Presenilin TMEM208_SND2 PF05620.11 CDJ51593.1 - 0.033 14.0 8.6 0.033 14.0 8.6 3.5 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Ribosomal_S21 PF01165.20 CDJ51594.1 - 0.027 14.2 3.7 0.04 13.6 2.9 1.8 1 1 0 1 1 1 0 Ribosomal protein S21 Ribosomal_L1 PF00687.21 CDJ51595.1 - 2.8e-41 141.5 4.0 3.6e-41 141.2 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_S24e PF01282.19 CDJ51596.1 - 2.2e-24 85.2 0.0 3.6e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e DUF4573 PF15140.6 CDJ51596.1 - 0.037 13.8 0.1 0.062 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) AAA_25 PF13481.6 CDJ51596.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Herpes_UL17 PF04559.12 CDJ51597.1 - 0.24 10.1 0.7 0.38 9.5 0.2 1.3 1 1 0 1 1 1 0 Herpesvirus UL17 protein DUF799 PF05643.11 CDJ51598.1 - 0.033 13.8 0.2 0.058 13.0 0.2 1.3 1 0 0 1 1 1 0 Putative bacterial lipoprotein (DUF799) WD40 PF00400.32 CDJ51599.1 - 7.4e-20 70.9 3.2 0.00092 20.0 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF3530 PF12048.8 CDJ51600.1 - 0.041 13.3 1.4 5.4 6.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Protamine_3 PF08188.11 CDJ51600.1 - 0.068 13.4 0.1 0.46 10.7 0.0 2.3 2 0 0 2 2 2 0 Spermatozal protamine family DUF3829 PF12889.7 CDJ51601.1 - 0.1 12.1 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) MCR_alpha_N PF02745.15 CDJ51601.1 - 0.21 10.9 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Plasmid_RAQPRD PF09686.10 CDJ51602.1 - 1.2 9.4 6.1 5.6 7.3 6.1 2.1 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Rer1 PF03248.13 CDJ51604.1 - 1.3e-61 207.3 2.6 1.6e-61 207.0 2.6 1.1 1 0 0 1 1 1 1 Rer1 family DUF5592 PF17332.2 CDJ51604.1 - 2.9 8.5 7.4 0.32 11.6 1.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5592) Bromodomain PF00439.25 CDJ51605.1 - 3.4e-33 113.6 0.0 6.4e-18 64.6 0.0 2.4 2 0 0 2 2 2 2 Bromodomain TFIIA PF03153.13 CDJ51606.1 - 0.19 11.7 20.4 0.2 11.6 20.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ51606.1 - 0.23 10.4 26.2 0.61 9.0 26.2 1.6 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4638 PF15472.6 CDJ51606.1 - 2.2 7.9 14.1 2.5 7.8 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) RR_TM4-6 PF06459.12 CDJ51606.1 - 2.6 7.8 13.1 3 7.6 13.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ51606.1 - 5.8 5.6 13.2 6.5 5.4 13.2 1.1 1 0 0 1 1 1 0 Presenilin ATP_bind_1 PF03029.17 CDJ51607.1 - 3.1e-63 213.8 0.0 8.3e-59 199.3 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CDJ51607.1 - 0.0001 22.8 0.0 0.0009 19.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ51607.1 - 0.00011 22.7 0.0 0.00011 22.7 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ51607.1 - 0.00011 22.5 0.0 0.00025 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 CDJ51607.1 - 0.0012 19.0 0.0 0.0018 18.3 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CLP1_P PF16575.5 CDJ51607.1 - 0.0019 18.0 0.0 0.0087 15.9 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_29 PF13555.6 CDJ51607.1 - 0.0022 17.7 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CDJ51607.1 - 0.0047 16.7 1.4 0.0079 15.9 0.0 2.1 3 0 0 3 3 1 1 AAA domain T2SSE PF00437.20 CDJ51607.1 - 0.0064 15.6 0.0 0.009 15.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CDJ51607.1 - 0.0075 16.8 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter PduV-EutP PF10662.9 CDJ51607.1 - 0.011 15.4 0.0 0.064 13.0 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4502 PF14950.6 CDJ51607.1 - 0.014 14.8 13.2 0.018 14.5 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) MeaB PF03308.16 CDJ51607.1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 CDJ51607.1 - 0.018 15.5 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.15 CDJ51607.1 - 0.024 13.8 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase Zeta_toxin PF06414.12 CDJ51607.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 CDJ51607.1 - 0.026 14.5 0.0 0.08 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Astro_capsid_p PF12226.8 CDJ51607.1 - 0.027 13.7 1.2 0.039 13.1 1.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Cytidylate_kin PF02224.18 CDJ51607.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase DUF815 PF05673.13 CDJ51607.1 - 0.039 13.1 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PAP1 PF08601.10 CDJ51607.1 - 0.041 13.6 10.4 0.057 13.2 10.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 RsgA_GTPase PF03193.16 CDJ51607.1 - 0.043 13.7 0.0 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 CDJ51607.1 - 0.046 13.4 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ51607.1 - 0.052 13.1 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 CDJ51607.1 - 0.053 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CDJ51607.1 - 0.057 13.6 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ51607.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 CDJ51607.1 - 0.072 12.8 0.0 5.2 6.7 0.0 2.4 2 1 0 2 2 2 0 Thymidylate kinase DDHD PF02862.17 CDJ51607.1 - 0.072 13.2 1.5 0.11 12.7 1.5 1.2 1 0 0 1 1 1 0 DDHD domain AAA_17 PF13207.6 CDJ51607.1 - 0.073 13.5 0.0 0.25 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 CDJ51607.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein KTI12 PF08433.10 CDJ51607.1 - 0.076 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 CDJ51607.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 CDJ51607.1 - 0.11 12.6 0.0 0.45 10.6 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 CDJ51607.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase YbjM PF11045.8 CDJ51607.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.6 1 1 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae AAA_PrkA PF08298.11 CDJ51607.1 - 0.12 11.3 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain Sigma54_activat PF00158.26 CDJ51607.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 CDJ51607.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TSC21 PF15217.6 CDJ51607.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 TSC21 family RNA_pol_Rpc4 PF05132.14 CDJ51607.1 - 0.64 10.4 4.6 1.5 9.3 4.6 1.6 1 1 0 1 1 1 0 RNA polymerase III RPC4 ASFV_J13L PF05568.11 CDJ51607.1 - 0.94 9.2 4.6 1.1 9.0 2.6 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein Nop14 PF04147.12 CDJ51607.1 - 1.1 7.3 14.0 1.5 6.9 14.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDJ51607.1 - 1.3 7.2 9.5 2 6.6 9.5 1.3 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 CDJ51607.1 - 1.8 7.7 6.4 2.9 7.0 6.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Raftlin PF15250.6 CDJ51607.1 - 2.3 6.9 6.4 3 6.5 6.4 1.2 1 0 0 1 1 1 0 Raftlin Paf1 PF03985.13 CDJ51607.1 - 7.5 5.4 13.3 48 2.8 0.0 2.1 2 0 0 2 2 2 0 Paf1 Presenilin PF01080.17 CDJ51607.1 - 7.7 5.2 8.1 11 4.6 8.1 1.2 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 CDJ51607.1 - 8.5 5.6 13.3 14 4.9 13.3 1.3 1 0 0 1 1 1 0 NOA36 protein DUF572 PF04502.13 CDJ51608.1 - 0.34 10.5 27.8 0.18 11.4 18.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) XRN_M PF17846.1 CDJ51608.1 - 0.79 8.6 21.0 0.39 9.6 17.1 2.0 2 0 0 2 2 2 0 Xrn1 helical domain Zip PF02535.22 CDJ51608.1 - 4.4 6.4 19.4 2.6 7.2 14.7 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter ALMT PF11744.8 CDJ51608.1 - 5.9 5.6 23.6 5.7 5.7 17.3 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter MRP-S31 PF15433.6 CDJ51608.1 - 6.5 6.3 33.1 6.3 6.4 27.0 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 DUF4667 PF15700.5 CDJ51609.1 - 0.012 15.7 4.6 0.016 15.3 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ51609.1 - 0.033 14.2 5.6 0.041 13.9 5.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CDJ51609.1 - 0.036 11.2 3.2 0.042 11.0 3.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SPX PF03105.19 CDJ51609.1 - 0.15 11.9 2.0 0.18 11.7 2.0 1.1 1 0 0 1 1 1 0 SPX domain PAP1 PF08601.10 CDJ51609.1 - 0.21 11.2 10.4 0.28 10.9 10.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF508 PF04370.12 CDJ51609.1 - 0.4 10.4 7.0 0.064 13.0 2.7 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF508) Ribosomal_60s PF00428.19 CDJ51609.1 - 0.48 11.0 26.4 0.25 11.9 12.0 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein IHABP4_N PF16174.5 CDJ51609.1 - 1.1 9.9 5.3 1.6 9.3 5.3 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF515 PF04415.12 CDJ51609.1 - 6.4 5.1 6.2 9 4.6 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pkinase PF00069.25 CDJ51610.1 - 1.1e-19 70.8 0.0 1.1e-19 70.8 0.0 2.8 4 0 0 4 4 4 1 Protein kinase domain Kinase-like PF14531.6 CDJ51610.1 - 1.6e-09 37.5 0.0 1.6e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ51610.1 - 9.3e-09 34.9 0.1 5.1e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CDJ51610.1 - 5.1e-05 22.7 0.1 0.00017 21.0 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2722 PF10846.8 CDJ51610.1 - 0.0046 16.0 43.7 0.014 14.4 14.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) U1snRNP70_N PF12220.8 CDJ51610.1 - 0.16 12.6 21.0 0.4 11.3 3.1 4.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ASD2 PF08687.11 CDJ51610.1 - 0.2 11.2 26.6 1.2 8.7 8.3 3.3 3 0 0 3 3 3 0 Apx/Shroom domain ASD2 Choline_kinase PF01633.20 CDJ51610.1 - 0.26 10.8 0.0 0.26 10.8 0.0 2.8 4 0 0 4 4 4 0 Choline/ethanolamine kinase OATP PF03137.20 CDJ51610.1 - 2.7 6.2 5.0 4.1 5.6 0.3 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAM60A PF15396.6 CDJ51610.1 - 3.1 7.7 11.1 5.7 6.9 0.3 2.9 3 0 0 3 3 3 0 Protein Family FAM60A Pkinase PF00069.25 CDJ51611.1 - 3.6e-21 75.7 0.0 1.5e-20 73.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ51611.1 - 1.6e-09 37.5 0.0 3.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ51611.1 - 2.5e-08 33.6 0.4 5.2e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CDJ51611.1 - 0.0098 15.5 1.1 2.6 7.6 0.0 3.2 1 1 2 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CDJ51611.1 - 0.019 13.8 3.8 0.2 10.4 3.8 2.0 1 1 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CDJ51611.1 - 0.034 13.5 0.0 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ51611.1 - 0.088 12.7 2.2 0.98 9.3 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family RCS1 PF07326.11 CDJ51613.1 - 0.04 13.8 1.1 0.073 13.0 0.8 1.6 1 1 1 2 2 2 0 Regulator of chromosome segregation 1 BatD PF13584.6 CDJ51614.1 - 6.1e-06 25.3 9.6 6.1e-06 25.3 9.6 2.8 2 1 1 3 3 3 2 Oxygen tolerance RskA PF10099.9 CDJ51614.1 - 0.00027 21.3 55.5 0.11 12.7 10.1 4.0 1 1 3 4 4 4 3 Anti-sigma-K factor rskA TRP PF06011.12 CDJ51614.1 - 0.0016 17.3 5.7 0.0028 16.5 5.7 1.4 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel ATAD4 PF15321.6 CDJ51614.1 - 0.012 17.0 5.7 0.012 17.0 5.7 3.9 4 0 0 4 4 4 0 ATPase family AAA domain containing 4 Ni_hydr_CYTB PF01292.20 CDJ51614.1 - 0.027 14.1 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 TssO PF17561.2 CDJ51614.1 - 0.029 14.5 2.2 0.029 14.5 2.2 3.6 4 0 0 4 4 3 0 Type VI secretion system, TssO DUF898 PF05987.13 CDJ51614.1 - 0.041 12.9 0.4 0.079 12.0 0.2 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF3357 PF11837.8 CDJ51614.1 - 0.12 12.8 0.5 0.12 12.8 0.5 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF3357) Utp14 PF04615.13 CDJ51614.1 - 0.18 10.3 36.4 0.14 10.7 35.3 1.3 1 1 0 1 1 1 0 Utp14 protein TRAP_alpha PF03896.16 CDJ51614.1 - 0.19 10.9 15.3 0.49 9.6 0.3 3.1 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit BPD_transp_2 PF02653.16 CDJ51614.1 - 0.71 9.0 3.2 1.8 7.7 2.5 1.9 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component Peptidase_S64 PF08192.11 CDJ51614.1 - 1.1 7.7 37.8 0.017 13.7 25.9 2.0 2 0 0 2 2 2 0 Peptidase family S64 DUF4149 PF13664.6 CDJ51614.1 - 1.8 8.9 7.5 19 5.6 7.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Yip1 PF04893.17 CDJ51614.1 - 1.9 8.2 10.6 0.25 11.0 2.7 2.8 3 1 1 4 4 4 0 Yip1 domain DUF4179 PF13786.6 CDJ51614.1 - 2.9 8.4 6.5 29 5.2 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4179) ETRAMP PF09716.10 CDJ51614.1 - 2.9 8.0 7.1 0.42 10.7 0.4 2.9 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Oxidored_q3 PF00499.20 CDJ51614.1 - 3.5 7.3 10.8 0.73 9.5 0.2 2.9 2 1 1 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Trp_oprn_chp PF09534.10 CDJ51614.1 - 3.9 7.2 19.3 0.16 11.7 1.9 3.0 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.6 CDJ51614.1 - 4.6 8.2 29.7 0.99 10.3 6.8 4.4 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain KASH PF10541.9 CDJ51614.1 - 5.1 7.4 9.5 0.89 9.9 4.5 2.1 2 0 0 2 2 2 0 Nuclear envelope localisation domain CCSAP PF15748.5 CDJ51614.1 - 7.4 6.7 45.0 0.88 9.7 27.7 2.4 1 1 1 2 2 2 0 Centriole, cilia and spindle-associated SprA-related PF12118.8 CDJ51615.1 - 0.0012 18.0 28.6 0.0018 17.5 28.6 1.3 1 0 0 1 1 1 1 SprA-related family TFIIA PF03153.13 CDJ51615.1 - 0.0032 17.5 31.9 0.0039 17.3 31.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 CDJ51615.1 - 0.1 11.0 1.8 0.13 10.6 1.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RskA PF10099.9 CDJ51615.1 - 0.69 10.2 54.2 6.9 6.9 33.4 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF4407 PF14362.6 CDJ51615.1 - 1 8.7 21.3 1.4 8.2 21.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Coilin_N PF15862.5 CDJ51615.1 - 1 9.2 14.1 5 6.9 9.7 2.2 2 0 0 2 2 2 0 Coilin N-terminus Serinc PF03348.15 CDJ51615.1 - 1.3 7.9 8.7 1.7 7.5 8.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SAPS PF04499.15 CDJ51615.1 - 1.4 7.6 9.2 1.7 7.4 9.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.11 CDJ51615.1 - 1.9 8.0 9.0 2.4 7.7 9.0 1.1 1 0 0 1 1 1 0 PPP4R2 Suf PF05843.14 CDJ51615.1 - 2.6 7.9 17.6 3.5 7.5 17.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hamartin PF04388.12 CDJ51615.1 - 3.3 6.3 12.8 3.6 6.1 12.8 1.1 1 0 0 1 1 1 0 Hamartin protein DivIC PF04977.15 CDJ51615.1 - 3.6 7.4 17.8 0.21 11.4 12.6 1.6 2 0 0 2 2 2 0 Septum formation initiator Trp_oprn_chp PF09534.10 CDJ51615.1 - 4.1 7.2 32.2 4.3 7.1 6.4 2.2 1 1 2 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PAT1 PF09770.9 CDJ51615.1 - 4.7 5.3 22.6 5.9 5.0 22.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 CDJ51615.1 - 4.8 6.0 16.1 6.2 5.7 16.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3408 PF11888.8 CDJ51615.1 - 6.3 6.9 17.6 12 6.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3408) eIF_4EBP PF05456.11 CDJ51615.1 - 8.6 6.3 14.0 9.1 6.3 6.9 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) FAM199X PF15814.5 CDJ51615.1 - 9 5.3 18.3 8.3 5.4 17.3 1.4 1 1 0 1 1 1 0 Protein family FAM199X CD20 PF04103.15 CDJ51615.1 - 9.2 6.3 7.2 1.8e+02 2.2 6.3 2.2 1 1 0 1 1 1 0 CD20-like family SR-25 PF10500.9 CDJ51616.1 - 0.0025 17.5 42.7 0.0025 17.5 42.7 13.7 10 3 1 13 13 13 3 Nuclear RNA-splicing-associated protein LST1 PF05083.13 CDJ51616.1 - 4.9 7.5 0.0 4.9 7.5 0.0 4.5 4 0 0 4 4 4 0 LST-1 protein RskA PF10099.9 CDJ51617.1 - 0.084 13.2 0.2 0.084 13.2 0.2 9.3 5 1 3 8 8 8 0 Anti-sigma-K factor rskA DUF92 PF01940.16 CDJ51618.1 - 0.0079 15.6 3.9 0.012 15.1 3.9 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 PIP49_C PF12260.8 CDJ51618.1 - 0.056 13.1 0.1 0.067 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 NST1 PF13945.6 CDJ51618.1 - 0.11 12.6 5.9 0.14 12.3 5.9 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator RTX PF02382.15 CDJ51618.1 - 0.16 11.6 19.1 0.2 11.3 19.1 1.0 1 0 0 1 1 1 0 N-terminal domain in RTX protein wnt PF00110.19 CDJ51618.1 - 0.28 10.8 5.4 0.36 10.4 5.4 1.3 1 0 0 1 1 1 0 wnt family Mitofilin PF09731.9 CDJ51618.1 - 0.45 9.3 14.0 0.51 9.1 14.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4820 PF16091.5 CDJ51618.1 - 0.46 9.8 5.0 0.56 9.5 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Spt20 PF12090.8 CDJ51618.1 - 0.54 9.8 7.2 0.62 9.6 7.2 1.2 1 0 0 1 1 1 0 Spt20 family RIFIN PF02009.16 CDJ51618.1 - 0.71 9.7 10.7 0.84 9.5 10.7 1.1 1 0 0 1 1 1 0 Rifin Suf PF05843.14 CDJ51618.1 - 0.92 9.4 5.8 1 9.3 5.8 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Lin-8 PF03353.15 CDJ51618.1 - 1.3 8.5 5.8 1.5 8.3 5.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.7 CDJ51618.1 - 1.8 6.6 5.1 1.9 6.5 5.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.13 CDJ51618.1 - 1.9 8.4 11.3 2.4 8.1 11.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit XRCC4 PF06632.12 CDJ51618.1 - 2.4 6.9 7.5 2.9 6.7 7.5 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Tic110 PF16940.5 CDJ51618.1 - 4.2 5.8 13.1 4.5 5.6 13.1 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter FAM199X PF15814.5 CDJ51618.1 - 4.4 6.3 12.7 5.1 6.1 12.7 1.1 1 0 0 1 1 1 0 Protein family FAM199X BAF1_ABF1 PF04684.13 CDJ51618.1 - 5.2 6.0 12.3 6 5.8 12.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF5427 PF10310.9 CDJ51618.1 - 7.1 5.5 14.5 8.3 5.3 14.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF3584 PF12128.8 CDJ51618.1 - 8.8 3.7 10.9 9.9 3.5 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Presenilin PF01080.17 CDJ51618.1 - 9.9 4.8 8.2 11 4.7 8.2 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ51619.1 - 1.5 7.0 40.8 1.6 6.9 40.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AF-4 PF05110.13 CDJ51619.1 - 2.9 5.9 41.8 4 5.4 41.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein HemX PF04375.14 CDJ51619.1 - 4.1 6.6 41.9 6.1 6.0 41.9 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Peptidase_S64 PF08192.11 CDJ51619.1 - 6.3 5.2 28.1 7.6 4.9 28.1 1.3 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.9 CDJ51619.1 - 6.3 5.2 30.8 7.8 4.9 30.8 1.1 1 0 0 1 1 1 0 Macoilin family Adenylsucc_synt PF00709.21 CDJ51620.1 - 1.2e-100 337.3 0.5 1e-63 215.8 0.0 2.2 2 0 0 2 2 2 2 Adenylosuccinate synthetase DUF1645 PF07816.11 CDJ51620.1 - 4.1e-05 24.3 2.2 4.1e-05 24.3 2.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1645) DUF5308 PF17233.2 CDJ51620.1 - 0.00059 20.1 17.4 0.057 13.7 3.5 3.3 3 0 0 3 3 3 2 Family of unknown function (DUF5308) Adaptin_binding PF10199.9 CDJ51620.1 - 0.0021 18.7 15.0 0.0042 17.7 0.0 2.5 1 1 1 2 2 1 1 Alpha and gamma adaptin binding protein p34 DUF4667 PF15700.5 CDJ51620.1 - 0.0045 17.1 22.4 0.057 13.5 0.4 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4667) SpoIIP PF07454.11 CDJ51620.1 - 0.0087 15.5 5.0 0.0087 15.5 5.0 2.5 3 0 0 3 3 3 1 Stage II sporulation protein P (SpoIIP) Ctr PF04145.15 CDJ51620.1 - 0.0095 16.6 10.1 0.74 10.4 0.7 3.1 3 0 0 3 3 3 2 Ctr copper transporter family CDC45 PF02724.14 CDJ51620.1 - 0.035 12.4 0.2 0.035 12.4 0.2 2.5 2 1 0 2 2 1 0 CDC45-like protein Neur_chan_memb PF02932.16 CDJ51620.1 - 0.21 11.6 15.8 0.2 11.7 0.4 2.8 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region TCP PF03634.13 CDJ51620.1 - 0.35 11.4 29.6 0.17 12.5 3.0 3.2 3 0 0 3 3 3 0 TCP family transcription factor Dpy19 PF10034.9 CDJ51620.1 - 0.54 8.4 2.6 6.4 4.8 0.1 2.1 2 0 0 2 2 2 0 Q-cell neuroblast polarisation DUF719 PF05334.13 CDJ51620.1 - 0.76 9.9 24.0 0.41 10.8 3.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF719) Otopetrin PF03189.13 CDJ51620.1 - 1 8.1 12.0 13 4.4 12.0 2.3 1 1 0 1 1 1 0 Otopetrin DUF913 PF06025.12 CDJ51620.1 - 1.1 8.1 18.6 4.9 6.0 3.9 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Plasmodium_Vir PF05795.11 CDJ51620.1 - 1.3 8.3 18.4 0.011 15.2 1.7 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein ABC2_membrane_2 PF12679.7 CDJ51620.1 - 3.6 6.8 10.5 3.1 7.0 0.2 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein FHIPEP PF00771.20 CDJ51620.1 - 6.2 5.2 16.5 0.96 7.8 3.1 2.3 2 0 0 2 2 2 0 FHIPEP family Peroxin-3 PF04882.12 CDJ51620.1 - 8.8 5.2 27.1 0.054 12.5 0.4 2.8 2 1 0 2 2 2 0 Peroxin-3 Presenilin PF01080.17 CDJ51622.1 - 0.33 9.7 38.4 0.43 9.3 38.4 1.1 1 0 0 1 1 1 0 Presenilin DUF2151 PF10221.9 CDJ51622.1 - 1.7 7.1 21.8 2 6.9 21.8 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator SLC12 PF03522.15 CDJ51622.1 - 1.9 7.4 37.0 2.3 7.1 37.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF572 PF04502.13 CDJ51622.1 - 4.2 6.9 35.1 7.1 6.1 35.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dapper PF15268.6 CDJ51622.1 - 4.5 6.0 37.2 5.3 5.8 37.2 1.0 1 0 0 1 1 1 0 Dapper CAC1F_C PF16885.5 CDJ51622.1 - 4.5 6.8 23.5 5.5 6.5 23.5 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term SOBP PF15279.6 CDJ51622.1 - 7.6 7.0 28.8 9.7 6.7 28.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Vfa1 PF08432.10 CDJ51622.1 - 8 6.7 41.3 11 6.3 41.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 CDJ51622.1 - 8.8 5.4 17.8 14 4.7 17.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter AARP2CN PF08142.12 CDJ51624.1 - 2.3e-09 37.2 0.0 2.3e-09 37.2 0.0 2.5 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA PF00004.29 CDJ51624.1 - 1.4e-05 25.5 0.0 7.5e-05 23.2 0.0 2.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 CDJ51624.1 - 6.5e-05 22.6 0.0 6.5e-05 22.6 0.0 2.4 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CDJ51624.1 - 0.00023 21.6 0.0 0.00023 21.6 0.0 4.3 5 0 0 5 5 5 1 AAA ATPase domain RNA_helicase PF00910.22 CDJ51624.1 - 0.0035 17.7 0.0 0.012 16.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 CDJ51624.1 - 0.0049 16.9 0.1 0.016 15.2 0.1 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RskA PF10099.9 CDJ51624.1 - 0.0072 16.6 68.3 0.23 11.7 13.1 5.9 5 1 0 5 5 5 3 Anti-sigma-K factor rskA MMR_HSR1 PF01926.23 CDJ51624.1 - 0.0073 16.4 0.0 0.025 14.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 CDJ51624.1 - 0.062 12.9 0.5 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CDJ51624.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 CDJ51624.1 - 0.17 12.0 0.0 0.17 12.0 0.0 3.9 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.6 CDJ51624.1 - 0.25 11.6 0.0 0.25 11.6 0.0 2.6 2 1 1 3 3 2 0 AAA domain IstB_IS21 PF01695.17 CDJ51624.1 - 0.26 11.0 2.9 0.86 9.3 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 CDJ51624.1 - 0.51 10.9 0.0 0.51 10.9 0.0 2.3 3 0 0 3 3 2 0 AAA domain Hexapep PF00132.24 CDJ51625.1 - 3.9e-08 32.7 9.7 6e-06 25.8 4.6 3.5 3 1 1 4 4 3 1 Bacterial transferase hexapeptide (six repeats) SPX PF03105.19 CDJ51625.1 - 0.0002 21.4 8.6 0.00025 21.1 8.6 1.1 1 0 0 1 1 1 1 SPX domain Fucokinase PF07959.12 CDJ51625.1 - 0.0036 16.3 5.2 0.0052 15.8 5.2 1.2 1 0 0 1 1 1 1 L-fucokinase DUF913 PF06025.12 CDJ51625.1 - 0.0039 16.2 0.7 0.0039 16.2 0.7 1.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) Apt1 PF10351.9 CDJ51625.1 - 0.0056 15.6 7.9 0.0084 15.0 7.9 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain Hexapep_2 PF14602.6 CDJ51625.1 - 0.018 14.8 7.7 0.13 12.1 1.8 3.0 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase CPSF100_C PF13299.6 CDJ51625.1 - 0.024 14.8 1.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4228 PF14009.6 CDJ51625.1 - 0.027 14.9 0.7 0.027 14.9 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) TLP-20 PF06088.11 CDJ51625.1 - 0.07 13.0 0.5 0.07 13.0 0.5 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) BUD22 PF09073.10 CDJ51625.1 - 0.083 12.2 9.7 0.17 11.2 9.7 1.5 1 1 0 1 1 1 0 BUD22 GREB1 PF15782.5 CDJ51625.1 - 0.21 8.6 4.0 0.29 8.2 4.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM176 PF14851.6 CDJ51625.1 - 0.37 10.5 5.4 3.5 7.3 3.6 2.1 2 0 0 2 2 2 0 FAM176 family POX PF07526.11 CDJ51625.1 - 0.38 11.3 8.8 0.26 11.9 5.6 2.0 2 0 0 2 2 2 0 Associated with HOX Coilin_N PF15862.5 CDJ51625.1 - 0.67 9.8 6.4 0.13 12.1 0.7 2.1 2 0 0 2 2 2 0 Coilin N-terminus CCDC53 PF10152.9 CDJ51625.1 - 1.3 9.4 12.1 1.6 9.1 3.9 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF1180 PF06679.12 CDJ51625.1 - 1.5 9.2 17.0 0.071 13.5 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SSP160 PF06933.11 CDJ51625.1 - 2 6.5 21.1 2.4 6.2 21.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FlgH PF02107.16 CDJ51625.1 - 2.4 7.8 10.5 5.1 6.7 10.5 1.5 1 0 0 1 1 1 0 Flagellar L-ring protein SpoIIIAH PF12685.7 CDJ51625.1 - 2.9 7.7 13.0 9.5 6.0 13.0 1.7 1 1 0 1 1 1 0 SpoIIIAH-like protein Striatin PF08232.12 CDJ51625.1 - 3.2 8.4 8.9 2.9 8.4 4.7 2.2 2 0 0 2 2 2 0 Striatin family Lin-8 PF03353.15 CDJ51625.1 - 3.8 7.0 6.9 5.2 6.5 5.2 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist RNA_pol_Rpc4 PF05132.14 CDJ51625.1 - 6.6 7.2 12.1 1.7 9.1 0.6 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 SAPS PF04499.15 CDJ51625.1 - 7.7 5.2 8.0 11 4.7 8.0 1.3 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein PSK PF06404.12 CDJ51625.1 - 8.4 7.5 7.0 38 5.4 1.8 2.5 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) SR-25 PF10500.9 CDJ51627.1 - 0.00036 20.2 17.6 0.00036 20.2 17.6 8.8 6 2 2 8 8 8 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ51627.1 - 0.00074 19.9 19.1 0.00074 19.9 19.1 15.0 5 3 5 12 12 12 2 Anti-sigma-K factor rskA Med15 PF09606.10 CDJ51627.1 - 0.0016 17.2 8.1 0.0016 17.2 8.1 7.3 4 2 1 5 5 5 1 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.9 CDJ51628.1 - 0.0022 18.3 17.0 0.0022 18.3 17.0 8.3 4 4 2 6 6 6 1 Anti-sigma-K factor rskA LUD_dom PF02589.15 CDJ51628.1 - 0.035 13.8 0.2 0.33 10.6 0.0 2.7 2 0 0 2 2 2 0 LUD domain Pet20 PF08692.10 CDJ51628.1 - 0.55 11.0 0.0 0.55 11.0 0.0 4.3 3 1 1 4 4 4 0 Mitochondrial protein Pet20 Endostatin PF06482.11 CDJ51628.1 - 6.1 6.2 43.7 3.9 6.9 11.1 3.5 3 0 0 3 3 3 0 Collagenase NC10 and Endostatin Vps53_N PF04100.12 CDJ51629.1 - 1.9e-19 69.9 29.1 9.8e-19 67.6 11.5 2.0 1 1 1 2 2 2 2 Vps53-like, N-terminal CDC45 PF02724.14 CDJ51629.1 - 0.00023 19.6 12.7 0.00024 19.6 12.7 1.3 1 0 0 1 1 1 1 CDC45-like protein Zip PF02535.22 CDJ51629.1 - 0.0023 17.2 6.3 0.003 16.8 6.3 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter ASC PF00858.24 CDJ51629.1 - 0.026 13.5 7.9 0.037 13.0 7.9 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel PAT1 PF09770.9 CDJ51629.1 - 0.036 12.4 47.4 0.051 11.8 47.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF913 PF06025.12 CDJ51629.1 - 0.039 12.9 14.5 0.058 12.4 14.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Med19 PF10278.9 CDJ51629.1 - 0.15 12.0 15.8 0.22 11.4 15.8 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Velvet PF11754.8 CDJ51629.1 - 0.15 12.0 20.0 0.26 11.2 20.0 1.5 1 0 0 1 1 1 0 Velvet factor GREB1 PF15782.5 CDJ51629.1 - 0.15 9.2 29.1 0.18 8.9 29.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lyase_8 PF02278.18 CDJ51629.1 - 0.23 10.9 10.6 0.32 10.4 10.6 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, super-sandwich domain DUF1387 PF07139.11 CDJ51629.1 - 0.26 11.0 28.6 0.37 10.5 28.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Hamartin PF04388.12 CDJ51629.1 - 0.35 9.5 24.2 0.41 9.3 24.2 1.1 1 0 0 1 1 1 0 Hamartin protein Pkinase_fungal PF17667.1 CDJ51629.1 - 0.38 9.5 15.0 0.49 9.1 15.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Hid1 PF12722.7 CDJ51629.1 - 0.55 8.3 24.8 0.66 8.0 24.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 CDJ51629.1 - 0.73 8.6 28.6 1.1 8.0 28.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter VIR_N PF15912.5 CDJ51629.1 - 0.99 9.0 13.4 1.3 8.5 13.4 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal RR_TM4-6 PF06459.12 CDJ51629.1 - 1.6 8.5 32.8 2.6 7.8 32.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mem_trans PF03547.18 CDJ51629.1 - 2.3 6.5 5.0 3.3 6.0 5.0 1.4 1 0 0 1 1 1 0 Membrane transport protein Cwf_Cwc_15 PF04889.12 CDJ51629.1 - 2.9 7.5 29.6 5.7 6.6 29.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SID-1_RNA_chan PF13965.6 CDJ51629.1 - 3.1 6.1 12.2 4.3 5.6 12.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDK5_activator PF03261.15 CDJ51629.1 - 3.9 6.9 21.9 5.5 6.4 21.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF2126 PF09899.9 CDJ51629.1 - 4.5 5.2 16.6 6.2 4.8 16.6 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2828 PF11443.8 CDJ51629.1 - 5 5.1 29.6 4.1 5.4 28.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2828) GAGA_bind PF06217.12 CDJ51629.1 - 5.2 7.3 28.0 7.6 6.7 28.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Abi_2 PF07751.11 CDJ51629.1 - 5.5 7.2 7.2 28 4.9 7.2 2.0 2 0 0 2 2 2 0 Abi-like protein DUF4045 PF13254.6 CDJ51629.1 - 6.7 6.2 29.3 9.8 5.7 29.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) LAP1C PF05609.12 CDJ51629.1 - 6.9 5.6 33.4 10 5.1 33.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Cellulose_synt PF03552.14 CDJ51629.1 - 9.1 4.6 10.3 12 4.2 10.3 1.2 1 0 0 1 1 1 0 Cellulose synthase DUF1635 PF07795.11 CDJ51630.1 - 0.0054 16.6 10.2 0.0054 16.6 10.2 4.3 3 1 0 3 3 3 1 Protein of unknown function (DUF1635) Cyt-b5 PF00173.28 CDJ51630.1 - 0.033 14.3 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Syja_N PF02383.18 CDJ51631.1 - 3.5e-31 108.7 0.0 3.3e-18 66.1 0.0 5.8 5 2 0 5 5 5 3 SacI homology domain EIF4E-T PF10477.9 CDJ51631.1 - 0.00051 19.0 0.7 0.00051 19.0 0.7 5.6 4 2 0 4 4 4 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF2722 PF10846.8 CDJ51631.1 - 0.00052 19.1 3.7 0.00052 19.1 3.7 7.8 7 1 1 8 8 8 5 Protein of unknown function (DUF2722) SPX PF03105.19 CDJ51631.1 - 0.0054 16.7 2.0 0.0054 16.7 2.0 4.7 3 2 1 4 4 4 2 SPX domain EOS1 PF12326.8 CDJ51631.1 - 1.6 8.6 31.7 1.2 9.0 0.5 5.7 5 1 0 5 5 5 0 N-glycosylation protein RskA PF10099.9 CDJ51632.1 - 0.00021 21.7 14.9 0.00021 21.7 14.9 10.4 6 5 2 8 8 8 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ51632.1 - 0.0012 18.5 23.2 0.0012 18.5 23.2 8.2 4 2 4 8 8 8 2 Spt20 family RAP1 PF07218.11 CDJ51633.1 - 0.076 11.3 5.5 0.092 11.0 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4207 PF13904.6 CDJ51634.1 - 0.0091 15.7 9.5 0.0091 15.7 9.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) DUF4407 PF14362.6 CDJ51634.1 - 0.027 13.8 5.9 0.036 13.4 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDJ51634.1 - 0.027 13.2 4.0 0.031 13.0 4.0 1.1 1 0 0 1 1 1 0 Presenilin DUF5345 PF17280.2 CDJ51634.1 - 0.059 13.4 0.4 0.059 13.4 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Orf78 PF06024.12 CDJ51634.1 - 0.18 12.1 2.3 9.7 6.6 2.2 2.1 2 0 0 2 2 2 0 Orf78 (ac78) DX PF01666.17 CDJ51634.1 - 0.23 11.9 4.0 0.33 11.4 0.2 2.3 2 1 0 2 2 2 0 DX module INSIG PF07281.12 CDJ51634.1 - 1.5 8.4 4.0 3 7.4 4.0 1.4 1 1 0 1 1 1 0 Insulin-induced protein (INSIG) DUF2681 PF10883.8 CDJ51634.1 - 2.1 8.8 28.1 0.14 12.5 9.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4770 PF15994.5 CDJ51634.1 - 4 7.7 15.5 1.7 8.9 6.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) G0-G1_switch_2 PF15103.6 CDJ51634.1 - 4.1 7.9 8.2 3.6 8.1 2.2 2.0 2 0 0 2 2 2 0 G0/G1 switch protein 2 TMEM51 PF15345.6 CDJ51634.1 - 4.2 7.1 12.3 1 9.2 3.6 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 IF4E PF01652.18 CDJ51635.1 - 4.1e-33 114.4 0.2 2.1e-32 112.2 0.2 1.8 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E FlaA PF04620.12 CDJ51637.1 - 0.18 11.4 0.6 0.27 10.9 0.6 1.3 1 0 0 1 1 1 0 Flagellar filament outer layer protein Flaa LAP1C PF05609.12 CDJ51638.1 - 0.061 12.4 51.4 0.075 12.1 51.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Trypan_PARP PF05887.11 CDJ51638.1 - 1.1 9.2 46.2 3.3 7.7 23.7 2.2 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) GREB1 PF15782.5 CDJ51638.1 - 8 3.4 43.7 9.7 3.2 43.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer F_actin_cap_B PF01115.17 CDJ51639.1 - 4.7e-25 88.6 1.4 9.8e-25 87.6 1.2 1.6 1 1 0 1 1 1 1 F-actin capping protein, beta subunit DUF2813 PF11398.8 CDJ51639.1 - 0.0054 16.0 2.8 0.0064 15.8 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) SpoIIP PF07454.11 CDJ51639.1 - 0.0055 16.2 8.9 0.0056 16.2 8.9 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 CDJ51639.1 - 0.0083 14.5 4.9 0.0096 14.3 4.9 1.1 1 0 0 1 1 1 1 CDC45-like protein Tim54 PF11711.8 CDJ51639.1 - 0.012 14.4 12.2 0.015 14.1 12.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.17 CDJ51639.1 - 0.013 15.7 6.8 0.014 15.6 6.8 1.1 1 0 0 1 1 1 0 DDHD domain Ndc1_Nup PF09531.10 CDJ51639.1 - 0.028 13.1 12.0 0.029 13.1 12.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 CDJ51639.1 - 0.029 14.4 33.0 0.035 14.1 33.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Eapp_C PF10238.9 CDJ51639.1 - 0.04 14.0 8.6 0.047 13.8 8.6 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein TERB2 PF15101.6 CDJ51639.1 - 0.042 13.9 13.9 0.051 13.6 13.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CobT PF06213.12 CDJ51639.1 - 0.052 12.9 20.0 0.071 12.5 20.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2828 PF11443.8 CDJ51639.1 - 0.053 11.6 7.9 0.056 11.5 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ51639.1 - 0.069 11.9 13.1 0.075 11.8 13.1 1.1 1 0 0 1 1 1 0 Presenilin DUF3408 PF11888.8 CDJ51639.1 - 0.075 13.2 11.1 0.11 12.7 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) R_equi_Vir PF05526.11 CDJ51639.1 - 0.092 12.6 4.9 0.12 12.2 4.9 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF4175 PF13779.6 CDJ51639.1 - 0.1 10.5 34.7 0.11 10.4 34.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NPR3 PF03666.13 CDJ51639.1 - 0.12 11.2 8.4 0.12 11.2 8.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFB6 PF17110.5 CDJ51639.1 - 0.12 12.1 4.3 0.18 11.5 4.3 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SOBP PF15279.6 CDJ51639.1 - 0.12 12.9 13.8 0.14 12.7 13.8 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein EPL1 PF10513.9 CDJ51639.1 - 0.13 12.6 12.5 0.22 11.9 12.5 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like SLC12 PF03522.15 CDJ51639.1 - 0.16 11.0 9.6 0.16 11.0 9.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Sec62 PF03839.16 CDJ51639.1 - 0.19 11.2 5.9 0.23 10.9 5.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 BNR_3 PF13859.6 CDJ51639.1 - 0.2 10.9 2.1 0.22 10.8 2.1 1.1 1 0 0 1 1 1 0 BNR repeat-like domain Peptidase_S64 PF08192.11 CDJ51639.1 - 0.24 9.8 7.6 0.25 9.8 7.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF5327 PF17261.2 CDJ51639.1 - 0.25 12.1 17.8 0.5 11.1 17.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5327) MMR1 PF08505.10 CDJ51639.1 - 0.26 11.5 13.4 0.3 11.3 13.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PAT1 PF09770.9 CDJ51639.1 - 0.27 9.5 24.2 0.3 9.3 24.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EIIBC-GUT_N PF03612.14 CDJ51639.1 - 0.3 10.8 10.7 0.4 10.4 10.7 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Hid1 PF12722.7 CDJ51639.1 - 0.33 9.0 14.7 0.38 8.8 14.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CPSF100_C PF13299.6 CDJ51639.1 - 0.34 11.1 10.8 0.43 10.8 10.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal eIF-3_zeta PF05091.12 CDJ51639.1 - 0.41 9.6 18.5 0.49 9.3 18.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MCD PF05292.11 CDJ51639.1 - 0.41 10.2 6.6 0.56 9.7 6.6 1.1 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain DUF913 PF06025.12 CDJ51639.1 - 0.45 9.4 7.8 0.51 9.3 7.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 CDJ51639.1 - 0.45 10.2 9.6 0.65 9.7 9.6 1.2 1 0 0 1 1 1 0 Connexin DUF2561 PF10812.8 CDJ51639.1 - 0.47 10.5 3.0 0.61 10.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Neur_chan_memb PF02932.16 CDJ51639.1 - 0.54 10.3 10.0 0.61 10.1 10.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4228 PF14009.6 CDJ51639.1 - 0.55 10.6 7.0 0.66 10.3 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF2370 PF10176.9 CDJ51639.1 - 0.58 9.8 5.2 0.77 9.4 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Hydin_ADK PF17213.3 CDJ51639.1 - 0.8 9.9 8.8 0.99 9.6 8.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RR_TM4-6 PF06459.12 CDJ51639.1 - 0.83 9.4 14.3 1 9.1 14.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 CDJ51639.1 - 0.86 8.8 4.3 0.92 8.7 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Plasmodium_Vir PF05795.11 CDJ51639.1 - 0.9 8.9 6.0 0.9 8.9 6.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Baculo_PP31 PF05311.11 CDJ51639.1 - 0.92 8.9 11.2 1.3 8.5 11.2 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FAM60A PF15396.6 CDJ51639.1 - 0.92 9.5 8.6 1.2 9.1 8.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Suf PF05843.14 CDJ51639.1 - 0.93 9.4 15.1 1.3 9.0 15.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) V_ATPase_I PF01496.19 CDJ51639.1 - 0.94 7.3 12.6 1.2 7.0 12.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CSG2 PF16965.5 CDJ51639.1 - 1 8.3 5.2 1.2 8.0 5.2 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Membralin PF09746.9 CDJ51639.1 - 1 8.4 3.8 1.1 8.3 3.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4770 PF15994.5 CDJ51639.1 - 1 9.6 14.7 1.3 9.2 14.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Lin-8 PF03353.15 CDJ51639.1 - 1.1 8.7 17.5 1.3 8.5 17.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PPL5 PF18168.1 CDJ51639.1 - 1.2 8.4 8.6 1.5 8.0 8.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Band_3_cyto PF07565.13 CDJ51639.1 - 1.4 8.7 12.3 1.7 8.4 12.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CLN3 PF02487.17 CDJ51639.1 - 1.4 7.8 9.0 1.8 7.5 9.0 1.1 1 0 0 1 1 1 0 CLN3 protein Folate_carrier PF01770.18 CDJ51639.1 - 1.5 7.5 4.7 1.8 7.2 4.7 1.1 1 0 0 1 1 1 0 Reduced folate carrier TraV PF09676.10 CDJ51639.1 - 1.5 9.8 16.3 2.6 9.0 16.4 1.4 1 1 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) FAM176 PF14851.6 CDJ51639.1 - 2 8.1 9.0 2.9 7.5 9.0 1.3 1 0 0 1 1 1 0 FAM176 family Gti1_Pac2 PF09729.9 CDJ51639.1 - 2.1 8.4 11.3 2.8 8.0 11.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DNApol_Exo PF18136.1 CDJ51639.1 - 2.1 7.4 12.1 2.8 7.0 12.1 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain GREB1 PF15782.5 CDJ51639.1 - 2.3 5.2 13.3 2.5 5.1 13.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NARP1 PF12569.8 CDJ51639.1 - 2.5 6.9 13.4 3.1 6.6 13.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MDM10 PF12519.8 CDJ51639.1 - 3.1 6.6 10.4 3.3 6.5 10.4 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 EOS1 PF12326.8 CDJ51639.1 - 3.1 7.7 5.2 4 7.3 5.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein Ureide_permease PF07168.11 CDJ51639.1 - 3.1 6.4 4.3 3.8 6.2 4.3 1.1 1 0 0 1 1 1 0 Ureide permease DUF4638 PF15472.6 CDJ51639.1 - 3.6 7.3 12.0 4.5 6.9 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF853 PF05872.12 CDJ51639.1 - 3.7 6.0 11.9 4.5 5.7 11.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3464 PF11947.8 CDJ51639.1 - 3.9 7.2 15.4 5.8 6.6 15.4 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Paf1 PF03985.13 CDJ51639.1 - 4.2 6.3 18.6 5.7 5.8 18.6 1.1 1 0 0 1 1 1 0 Paf1 DUF2126 PF09899.9 CDJ51639.1 - 4.3 5.3 9.5 5.2 5.0 9.5 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) ALMT PF11744.8 CDJ51639.1 - 4.4 6.0 8.9 5.3 5.8 8.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0560 PF10577.9 CDJ51639.1 - 5.7 5.3 21.2 7.2 5.0 21.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MAJIN PF15077.6 CDJ51639.1 - 6.7 6.4 10.5 8 6.2 10.5 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein SID-1_RNA_chan PF13965.6 CDJ51639.1 - 6.8 5.0 5.6 7.9 4.8 5.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.10 CDJ51639.1 - 8.2 6.5 12.0 13 5.9 12.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal XRN_N PF03159.18 CDJ51639.1 - 8.4 5.7 11.7 11 5.3 11.7 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DUF1980 PF09323.10 CDJ51639.1 - 8.6 6.2 9.4 11 5.9 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Serinc PF03348.15 CDJ51639.1 - 8.6 5.2 8.3 10 4.9 8.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Paramyxo_ncap PF00973.19 CDJ51639.1 - 8.8 5.1 9.6 9.6 5.0 9.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Pkinase PF00069.25 CDJ51640.1 - 5.9e-08 32.4 0.0 5.9e-08 32.4 0.0 4.8 7 0 0 7 7 7 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ51640.1 - 0.00089 18.6 1.9 0.0043 16.4 0.0 3.0 4 0 0 4 4 4 1 Protein tyrosine kinase NPR3 PF03666.13 CDJ51641.1 - 0.7 8.6 17.9 0.75 8.5 17.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MMR1 PF08505.10 CDJ51641.1 - 1.9 8.7 27.0 2.1 8.6 27.0 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein AUX_IAA PF02309.16 CDJ51641.1 - 4.7 7.0 16.6 6.1 6.6 16.6 1.2 1 0 0 1 1 1 0 AUX/IAA family TFIIA PF03153.13 CDJ51641.1 - 7.3 6.5 46.4 8.7 6.2 46.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Paf1 PF03985.13 CDJ51641.1 - 8.1 5.3 20.1 11 4.9 20.1 1.2 1 0 0 1 1 1 0 Paf1 FAM60A PF15396.6 CDJ51641.1 - 9.3 6.2 17.8 10 6.1 17.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ51641.1 - 9.9 5.9 22.1 11 5.7 22.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SR-25 PF10500.9 CDJ51643.1 - 0.00071 19.3 14.9 0.00071 19.3 14.9 4.4 1 1 3 5 5 5 3 Nuclear RNA-splicing-associated protein DUF202 PF02656.15 CDJ51644.1 - 2.7e-10 40.5 7.7 2.7e-10 40.5 7.7 9.8 6 2 1 7 7 7 1 Domain of unknown function (DUF202) SPX PF03105.19 CDJ51644.1 - 1.8e-09 38.0 12.6 1.8e-09 38.0 12.6 5.3 3 2 0 3 3 3 2 SPX domain VTC PF09359.10 CDJ51644.1 - 0.00027 20.5 0.4 0.01 15.2 0.1 3.0 2 1 0 2 2 2 1 VTC domain Spt20 PF12090.8 CDJ51646.1 - 0.0007 19.3 6.6 0.00073 19.2 6.6 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ51646.1 - 0.0011 18.0 1.9 0.0011 18.0 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) MOZART1 PF12554.8 CDJ51646.1 - 0.085 12.7 0.3 0.35 10.7 0.1 1.9 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Mitofilin PF09731.9 CDJ51646.1 - 0.3 9.9 7.5 0.33 9.8 7.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DLIC PF05783.11 CDJ51646.1 - 3.8 6.2 7.5 4.9 5.9 7.5 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Activator_LAG-3 PF11498.8 CDJ51646.1 - 4.3 6.2 16.8 5.9 5.7 16.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3027 PF11228.8 CDJ51648.1 - 1.5 8.8 10.1 1.7 8.6 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) DUF572 PF04502.13 CDJ51648.1 - 2.7 7.6 16.9 2.7 7.5 16.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) CAF-1_p150 PF11600.8 CDJ51648.1 - 6.2 6.5 21.4 8.5 6.0 21.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Presenilin PF01080.17 CDJ51648.1 - 7.6 5.2 25.3 8.4 5.0 25.3 1.0 1 0 0 1 1 1 0 Presenilin Velvet PF11754.8 CDJ51648.1 - 9 6.1 18.7 11 5.9 18.7 1.1 1 0 0 1 1 1 0 Velvet factor DUF4569 PF15133.6 CDJ51648.1 - 9.9 5.8 22.5 11 5.6 22.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) AMP-binding PF00501.28 CDJ51649.1 - 2.6e-43 148.2 0.2 5.1e-43 147.2 0.2 1.4 1 0 0 1 1 1 1 AMP-binding enzyme DUF2722 PF10846.8 CDJ51649.1 - 0.00011 21.3 8.6 0.0086 15.1 2.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ51649.1 - 0.0015 18.6 14.4 0.017 15.2 3.2 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ51649.1 - 0.021 14.5 26.4 0.42 10.2 12.5 2.3 2 0 0 2 2 2 0 Spt20 family FAM212 PF15342.6 CDJ51649.1 - 0.063 13.1 1.4 0.73 9.7 0.0 3.0 3 0 0 3 3 3 0 FAM212 family IER PF05760.12 CDJ51649.1 - 0.088 13.1 9.3 0.21 11.9 3.7 2.5 2 0 0 2 2 2 0 Immediate early response protein (IER) DUF3381 PF11861.8 CDJ51649.1 - 0.25 11.1 5.6 2.3 8.0 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) BRF1 PF07741.13 CDJ51649.1 - 0.25 11.7 2.4 12 6.3 0.2 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain FYDLN_acid PF09538.10 CDJ51649.1 - 0.65 10.7 3.0 0.68 10.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Pex14_N PF04695.13 CDJ51649.1 - 1.1 9.9 10.8 5.5 7.6 0.8 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RuvC_III PF18541.1 CDJ51649.1 - 2.1 8.3 5.4 8.7 6.2 1.0 2.1 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 PID_2 PF14719.6 CDJ51649.1 - 5.1 6.9 6.9 0.38 10.6 0.2 2.0 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) UPF0560 PF10577.9 CDJ51649.1 - 6 5.2 10.8 1.1 7.6 1.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Suf PF05843.14 CDJ51649.1 - 8.9 6.2 10.4 7 6.5 2.1 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.8 CDJ51649.1 - 9.1 5.1 39.3 2.3 7.1 12.7 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 AP2 PF00847.20 CDJ51650.1 - 2.1e-09 37.5 0.4 2.1e-09 37.5 0.4 4.7 3 0 0 3 3 3 1 AP2 domain Caldesmon PF02029.15 CDJ51650.1 - 0.00048 19.0 13.3 0.00048 19.0 13.3 5.9 4 2 1 5 5 5 1 Caldesmon SUIM_assoc PF16619.5 CDJ51650.1 - 0.0053 16.8 0.0 0.0053 16.8 0.0 19.2 12 5 1 13 13 13 4 Unstructured region C-term to UIM in Ataxin3 SPX PF03105.19 CDJ51652.1 - 0.14 12.1 8.2 0.16 11.9 8.2 1.1 1 0 0 1 1 1 0 SPX domain ATF7IP_BD PF16788.5 CDJ51652.1 - 0.16 12.1 4.4 0.2 11.7 4.4 1.1 1 0 0 1 1 1 0 ATF-interacting protein binding domain Apt1 PF10351.9 CDJ51652.1 - 0.31 9.9 9.2 0.33 9.8 9.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 CDJ51652.1 - 1.7 5.6 7.3 1.8 5.6 7.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCDC106 PF15794.5 CDJ51652.1 - 3.8 7.2 9.5 5.1 6.7 9.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PAP1 PF08601.10 CDJ51652.1 - 4.1 7.0 18.9 4.8 6.8 18.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Secretin_N_2 PF07655.13 CDJ51652.1 - 7.4 7.2 22.1 12 6.5 22.1 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain SR-25 PF10500.9 CDJ51653.1 - 0.0013 18.4 10.3 0.0013 18.4 10.3 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Med15 PF09606.10 CDJ51653.1 - 1.7 7.2 26.7 1.8 7.1 26.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ51653.1 - 3.8 7.4 30.0 5.8 6.8 30.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ51654.1 - 4.1e-08 33.7 43.9 0.0019 18.5 4.3 3.4 1 1 2 3 3 3 3 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ51654.1 - 7.9e-06 25.1 6.7 7.9e-06 25.1 6.7 3.4 3 1 0 3 3 3 2 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ51654.1 - 0.0016 17.2 43.5 0.017 13.8 30.5 2.3 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.9 CDJ51654.1 - 0.0021 17.7 0.3 0.0021 17.7 0.3 6.1 6 0 0 6 6 6 2 Nuclear RNA-splicing-associated protein RPA43_OB PF17875.1 CDJ51654.1 - 0.0043 17.7 6.2 0.031 14.9 0.5 3.4 3 0 0 3 3 3 1 RPA43 OB domain in RNA Pol I TctB PF07331.11 CDJ51654.1 - 0.023 15.0 1.0 1.1 9.5 0.1 2.7 3 0 0 3 3 2 0 Tripartite tricarboxylate transporter TctB family Otopetrin PF03189.13 CDJ51654.1 - 0.15 10.8 0.0 0.15 10.8 0.0 2.5 3 0 0 3 3 3 0 Otopetrin eIF-3_zeta PF05091.12 CDJ51654.1 - 0.17 10.8 17.6 2.9 6.8 8.8 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rxt3 PF08642.10 CDJ51654.1 - 0.36 11.6 9.0 0.77 10.5 0.2 3.6 4 0 0 4 4 4 0 Histone deacetylation protein Rxt3 UPF0564 PF10595.9 CDJ51654.1 - 0.53 9.3 0.0 0.53 9.3 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0564 AAT PF03417.16 CDJ51654.1 - 1.3 8.7 9.3 0.16 11.6 2.6 2.5 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF1645 PF07816.11 CDJ51654.1 - 1.6 9.3 39.4 0.73 10.4 8.6 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1645) SpoIIP PF07454.11 CDJ51654.1 - 1.6 8.1 12.6 0.2 11.1 0.4 3.1 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) HA2 PF04408.23 CDJ51654.1 - 1.9 8.8 9.2 16 5.8 0.9 3.7 3 0 0 3 3 3 0 Helicase associated domain (HA2) DUF4834 PF16118.5 CDJ51654.1 - 2.8 8.9 32.7 1.3 10.0 8.4 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) CrgA PF06781.12 CDJ51654.1 - 3.4 7.8 5.2 4.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Cell division protein CrgA Connexin PF00029.19 CDJ51654.1 - 3.8 7.2 7.9 1.7 8.4 0.4 3.0 3 0 0 3 3 3 0 Connexin DUF4770 PF15994.5 CDJ51654.1 - 6.5 6.9 21.6 7.3 6.8 7.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) DUF5320 PF17253.2 CDJ51654.1 - 7.1 7.8 14.4 2 9.5 1.8 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5320) Suf PF05843.14 CDJ51655.1 - 0.0045 17.0 2.6 0.0045 17.0 2.6 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) dsRBD2 PF17842.1 CDJ51655.1 - 0.023 14.9 1.3 0.03 14.5 1.3 1.2 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 V_ATPase_I PF01496.19 CDJ51655.1 - 0.066 11.1 1.7 0.077 10.9 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ51655.1 - 9.5 6.1 29.5 13 5.6 29.5 1.2 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YscO-like PF16789.5 CDJ51657.1 - 0.19 11.8 16.9 0.24 11.4 16.9 1.1 1 0 0 1 1 1 0 YscO-like protein V_ATPase_I PF01496.19 CDJ51657.1 - 4 5.2 10.7 4.5 5.1 10.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.14 CDJ51657.1 - 4.7 7.6 29.4 5.2 7.4 29.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YlqD PF11068.8 CDJ51657.1 - 8.1 6.8 31.7 10 6.5 31.7 1.2 1 0 0 1 1 1 0 YlqD protein Trp_oprn_chp PF09534.10 CDJ51658.1 - 0.087 12.6 1.5 0.11 12.3 1.5 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TFIIA PF03153.13 CDJ51658.1 - 0.35 10.8 27.6 0.41 10.6 27.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AP1AR PF15745.5 CDJ51658.1 - 1.4 8.5 6.3 1.6 8.3 6.3 1.0 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein CDK2AP PF09806.9 CDJ51658.1 - 1.5 8.8 12.1 2.3 8.2 12.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Sin_N PF04801.13 CDJ51658.1 - 2.9 7.0 17.2 3.4 6.8 17.2 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Presenilin PF01080.17 CDJ51658.1 - 3.8 6.2 9.3 4.3 6.0 9.3 1.1 1 0 0 1 1 1 0 Presenilin AFG1_ATPase PF03969.16 CDJ51658.1 - 4.2 6.2 7.4 5.2 5.8 7.4 1.0 1 0 0 1 1 1 0 AFG1-like ATPase eIF-3_zeta PF05091.12 CDJ51658.1 - 8 5.3 14.0 10 4.9 14.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SR-25 PF10500.9 CDJ51659.1 - 2.3 7.7 11.7 0.35 10.5 7.4 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ51660.1 - 4.5 5.9 43.9 6.4 5.4 43.9 1.3 1 0 0 1 1 1 0 Presenilin DUF4467 PF14729.6 CDJ51661.1 - 0.051 13.9 1.4 0.14 12.5 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) Pox_A12 PF04651.13 CDJ51661.1 - 1.2 9.2 5.1 2.2 8.3 5.1 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein Consortin_C PF15281.6 CDJ51661.1 - 5.5 7.0 5.1 1.9 8.5 1.7 1.9 2 0 0 2 2 2 0 Consortin C-terminus CCDC106 PF15794.5 CDJ51661.1 - 6.6 6.4 17.9 1.8 8.2 8.9 3.0 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 106 Macoilin PF09726.9 CDJ51661.1 - 8.2 4.8 11.2 0.49 8.9 4.0 2.1 2 0 0 2 2 2 0 Macoilin family DUF1645 PF07816.11 CDJ51661.1 - 9.2 6.8 20.0 0.67 10.5 8.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ51662.1 - 0.0042 16.7 9.1 0.0062 16.2 9.1 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Med15 PF09606.10 CDJ51664.1 - 3.9 6.0 46.0 4.5 5.8 46.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Symplekin_C PF12295.8 CDJ51666.1 - 2.7e-37 128.7 3.8 3.7e-37 128.2 1.0 2.4 2 1 0 2 2 2 1 Symplekin tight junction protein C terminal DUF2722 PF10846.8 CDJ51666.1 - 1.1e-07 31.2 4.8 8.7e-07 28.2 3.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) BRF1 PF07741.13 CDJ51666.1 - 0.00063 20.1 1.9 0.00063 20.1 1.9 3.0 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TMEM51 PF15345.6 CDJ51666.1 - 0.014 15.2 2.5 0.014 15.2 2.5 2.3 3 0 0 3 3 3 0 Transmembrane protein 51 Eapp_C PF10238.9 CDJ51666.1 - 0.022 14.9 0.8 0.022 14.9 0.8 2.5 3 0 0 3 3 3 0 E2F-associated phosphoprotein Pex14_N PF04695.13 CDJ51666.1 - 0.024 15.3 6.3 0.024 15.3 6.3 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PMI_typeI PF01238.21 CDJ51666.1 - 0.024 13.8 2.3 0.048 12.9 2.3 1.4 1 0 0 1 1 1 0 Phosphomannose isomerase type I PEX11 PF05648.14 CDJ51666.1 - 0.026 14.0 3.5 0.027 13.9 1.9 1.8 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) EPL1 PF10513.9 CDJ51666.1 - 0.037 14.4 1.0 0.037 14.4 1.0 2.3 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF4228 PF14009.6 CDJ51666.1 - 0.062 13.7 7.7 0.15 12.4 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Connexin PF00029.19 CDJ51666.1 - 0.082 12.7 1.7 0.19 11.5 1.7 1.6 1 0 0 1 1 1 0 Connexin Tim54 PF11711.8 CDJ51666.1 - 0.14 10.9 4.3 0.2 10.4 1.0 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Ctr PF04145.15 CDJ51666.1 - 0.19 12.3 1.8 0.74 10.4 0.3 2.2 2 0 0 2 2 2 0 Ctr copper transporter family CPSF100_C PF13299.6 CDJ51666.1 - 0.36 11.0 12.2 0.24 11.6 1.3 2.6 3 0 0 3 3 2 0 Cleavage and polyadenylation factor 2 C-terminal AAA_23 PF13476.6 CDJ51666.1 - 0.47 10.9 8.6 1 9.8 8.6 1.5 1 0 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.12 CDJ51666.1 - 0.55 9.1 9.5 1.1 8.2 9.5 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rxt3 PF08642.10 CDJ51666.1 - 0.56 11.0 3.3 0.5 11.1 1.0 2.0 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 MecA PF05389.12 CDJ51666.1 - 0.7 9.5 9.1 0.061 13.0 3.2 2.0 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF4834 PF16118.5 CDJ51666.1 - 0.93 10.5 14.3 0.36 11.8 8.9 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) CCDC53 PF10152.9 CDJ51666.1 - 1 9.8 18.9 0.14 12.5 1.3 3.3 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex PRC2_HTH_1 PF18118.1 CDJ51666.1 - 1 10.2 5.6 0.24 12.2 1.0 2.2 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Het-C PF07217.11 CDJ51666.1 - 1 7.8 6.1 8.7 4.7 5.2 2.0 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C RR_TM4-6 PF06459.12 CDJ51666.1 - 2.1 8.1 12.5 7.9 6.2 6.5 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 CDJ51666.1 - 3.1 7.2 10.0 0.15 11.5 3.8 1.9 2 1 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Rtf2 PF04641.12 CDJ51666.1 - 4.8 6.5 15.2 0.23 10.8 1.5 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger CLN3 PF02487.17 CDJ51666.1 - 5.2 6.0 5.4 1.5 7.8 1.6 1.9 2 0 0 2 2 2 0 CLN3 protein KCNQ2_u3 PF16642.5 CDJ51666.1 - 6.3 7.8 10.6 2.8 9.0 4.6 2.8 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 HGTP_anticodon2 PF12745.7 CDJ51666.1 - 6.6 6.2 13.5 6.7 6.1 5.2 2.4 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs AIF_C PF14721.6 CDJ51666.1 - 6.9 7.0 11.5 6.1 7.2 5.5 2.5 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Activator_LAG-3 PF11498.8 CDJ51666.1 - 9 5.1 46.4 5.7 5.8 33.7 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Peroxin-13_N PF04088.13 CDJ51666.1 - 9.7 6.5 9.0 0.61 10.4 2.3 2.3 2 1 1 3 3 3 0 Peroxin 13, N-terminal region CAF1C_H4-bd PF12265.8 CDJ51667.1 - 6.6e-17 61.5 0.2 3.5e-16 59.2 0.0 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CDJ51667.1 - 0.0013 19.5 7.9 0.15 13.0 0.0 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF1645 PF07816.11 CDJ51667.1 - 4.9 7.7 29.0 0.46 11.0 0.5 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1645) XK-related PF09815.9 CDJ51667.1 - 6 5.8 9.9 11 5.0 9.9 1.4 1 0 0 1 1 1 0 XK-related protein DUF3533 PF12051.8 CDJ51667.1 - 7.1 5.4 8.4 13 4.6 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Octopine_DH PF02317.17 CDJ51669.1 - 0.078 13.1 0.3 7.9 6.6 0.3 2.5 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF5072 PF16807.5 CDJ51669.1 - 0.15 12.1 1.2 6.6 6.8 0.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF5072) ICA69 PF04629.14 CDJ51669.1 - 0.23 11.8 5.8 1.6 9.0 1.3 2.9 2 1 1 3 3 3 0 Islet cell autoantigen ICA69, C-terminal domain HSP90 PF00183.18 CDJ51670.1 - 3.8e-07 29.4 0.1 4.6e-07 29.1 0.1 1.0 1 0 0 1 1 1 1 Hsp90 protein cNMPbd_u2 PF16643.5 CDJ51673.1 - 0.16 12.4 2.2 0.36 11.3 0.5 2.3 2 1 1 3 3 3 0 Unstructured region on cNMP-binding protein DUF1079 PF06435.11 CDJ51675.1 - 0.33 11.2 5.4 11 6.3 0.7 2.8 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) SVIP PF15811.5 CDJ51675.1 - 4.5 7.8 7.1 0.41 11.1 0.4 2.8 3 0 0 3 3 3 0 Small VCP/p97-interacting protein GDI PF00996.18 CDJ51677.1 - 1.5e-104 349.9 4.7 2.8e-52 177.7 0.0 3.0 1 1 1 3 3 3 3 GDP dissociation inhibitor SBDS PF01172.18 CDJ51678.1 - 1.1e-09 38.2 0.0 3.2e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 CDJ51678.1 - 2.3e-07 30.8 0.0 2.3e-07 30.8 0.0 3.5 3 2 0 3 3 3 1 SBDS protein C-terminal domain Utp14 PF04615.13 CDJ51680.1 - 2.2e-24 86.1 92.5 2.2e-20 72.9 68.6 2.5 1 1 0 2 2 2 2 Utp14 protein TMEM51 PF15345.6 CDJ51680.1 - 0.007 16.2 3.1 0.007 16.2 3.1 4.7 4 2 1 5 5 5 1 Transmembrane protein 51 SR-25 PF10500.9 CDJ51682.1 - 0.0017 18.0 36.1 0.0017 18.0 36.1 5.2 2 1 2 5 5 5 2 Nuclear RNA-splicing-associated protein DUF1387 PF07139.11 CDJ51683.1 - 9.6 5.8 30.2 12 5.5 30.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) GDPD PF03009.17 CDJ51684.1 - 6e-18 65.5 4.5 3.3e-17 63.1 4.5 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Presenilin PF01080.17 CDJ51684.1 - 3.2e-05 22.9 15.4 4.9e-05 22.3 15.4 1.3 1 0 0 1 1 1 1 Presenilin PAT1 PF09770.9 CDJ51684.1 - 0.00025 19.5 26.0 0.00031 19.2 26.0 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Raftlin PF15250.6 CDJ51684.1 - 0.0017 17.2 8.7 0.0023 16.8 8.7 1.2 1 0 0 1 1 1 1 Raftlin SID-1_RNA_chan PF13965.6 CDJ51684.1 - 0.0028 16.2 0.3 0.0034 15.9 0.3 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Zip PF02535.22 CDJ51684.1 - 0.011 14.9 6.8 0.033 13.4 6.4 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter EpsG PF14897.6 CDJ51684.1 - 0.022 14.1 0.5 0.081 12.2 0.4 1.8 2 0 0 2 2 2 0 EpsG family Tim54 PF11711.8 CDJ51684.1 - 0.056 12.2 13.0 0.093 11.5 13.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Dynactin_p62 PF05502.13 CDJ51684.1 - 0.083 11.7 14.2 0.11 11.3 14.2 1.1 1 0 0 1 1 1 0 Dynactin p62 family PgaD PF13994.6 CDJ51684.1 - 0.1 12.6 0.0 0.1 12.6 0.0 2.7 3 0 0 3 3 2 0 PgaD-like protein CDC45 PF02724.14 CDJ51684.1 - 0.15 10.3 23.7 0.21 9.8 23.7 1.1 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.12 CDJ51684.1 - 0.16 12.3 19.1 0.27 11.5 19.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.16 CDJ51684.1 - 0.4 10.7 15.8 0.63 10.0 15.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2828 PF11443.8 CDJ51684.1 - 0.63 8.1 18.1 0.97 7.4 18.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TFIIA PF03153.13 CDJ51684.1 - 0.72 9.8 41.8 1.6 8.6 41.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec62 PF03839.16 CDJ51684.1 - 1.3 8.5 24.0 2.1 7.8 24.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Vfa1 PF08432.10 CDJ51684.1 - 1.5 9.2 27.7 2.4 8.5 27.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 CDJ51684.1 - 2 8.2 27.6 3.3 7.5 27.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CDJ51684.1 - 4.8 4.2 19.9 7.6 3.5 19.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 CDJ51684.1 - 5.8 5.9 23.4 8.2 5.4 23.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Dsh_C PF12316.8 CDJ51684.1 - 8.4 6.7 25.7 11 6.4 9.3 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4746 PF15928.5 CDJ51685.1 - 1.9 7.9 24.6 2.9 7.3 24.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop53 PF07767.11 CDJ51685.1 - 6.4 6.1 37.1 7.3 5.9 37.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RskA PF10099.9 CDJ51686.1 - 0.0068 16.7 2.2 0.009 16.3 2.2 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF1980 PF09323.10 CDJ51686.1 - 0.0068 16.3 1.4 0.0097 15.8 1.4 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1980) DUF4179 PF13786.6 CDJ51686.1 - 0.95 10.0 6.8 0.35 11.4 3.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) TFIIA PF03153.13 CDJ51687.1 - 0.066 13.2 20.2 0.082 12.9 20.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ51687.1 - 0.86 10.6 4.8 1.1 10.2 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ51687.1 - 1.3 8.6 13.3 1.9 8.0 13.3 1.2 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ51687.1 - 3.4 6.4 5.2 4 6.1 5.2 1.1 1 0 0 1 1 1 0 Presenilin Dus PF01207.17 CDJ51688.1 - 1.4e-19 70.4 7.2 1.4e-19 70.4 7.2 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 CDJ51688.1 - 0.00089 18.6 0.1 0.0016 17.7 0.1 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Macoilin PF09726.9 CDJ51688.1 - 0.0019 16.9 21.1 0.039 12.5 1.8 2.1 2 0 0 2 2 2 2 Macoilin family DUF3446 PF11928.8 CDJ51688.1 - 0.0037 17.6 4.1 0.0037 17.6 4.1 5.5 3 1 1 4 4 3 1 Early growth response N-terminal domain Activator_LAG-3 PF11498.8 CDJ51688.1 - 0.0046 16.0 31.5 0.012 14.6 31.5 1.8 1 0 0 1 1 1 1 Transcriptional activator LAG-3 His_biosynth PF00977.21 CDJ51688.1 - 0.015 14.8 0.2 0.027 13.9 0.2 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein G3P_antiterm PF04309.12 CDJ51688.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Pox_G5 PF04599.12 CDJ51688.1 - 0.21 10.6 1.3 0.32 10.0 1.3 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein Neur_chan_memb PF02932.16 CDJ51688.1 - 1.2 9.1 12.2 0.37 10.8 5.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.16 CDJ51688.1 - 1.3 7.9 4.5 1.8 7.4 4.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Miga PF10265.9 CDJ51688.1 - 1.7 7.5 26.8 0.2 10.6 9.9 2.1 2 0 0 2 2 2 0 Mitoguardin OmpH PF03938.14 CDJ51688.1 - 4.4 7.6 23.0 9.9 6.5 23.0 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Lin-8 PF03353.15 CDJ51688.1 - 5.7 6.4 22.2 0.22 11.0 10.7 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 CDJ51688.1 - 6.3 3.8 24.9 0.23 8.5 13.3 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer SID-1_RNA_chan PF13965.6 CDJ51689.1 - 0.0022 16.5 0.7 0.0022 16.5 0.7 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 PIP5K PF01504.18 CDJ51689.1 - 0.011 14.9 10.3 0.014 14.6 10.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase TFIIA PF03153.13 CDJ51689.1 - 0.012 15.6 52.8 0.017 15.2 52.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 CDJ51689.1 - 0.02 13.7 10.3 0.021 13.6 10.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Smg8_Smg9 PF10220.9 CDJ51689.1 - 0.2 10.0 13.8 0.18 10.1 13.8 1.2 1 0 0 1 1 1 0 Smg8_Smg9 PPP4R2 PF09184.11 CDJ51689.1 - 0.2 11.2 11.2 0.22 11.1 11.2 1.1 1 0 0 1 1 1 0 PPP4R2 PA26 PF04636.13 CDJ51689.1 - 0.27 10.1 10.9 0.35 9.7 10.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Endostatin PF06482.11 CDJ51689.1 - 0.31 10.5 14.5 0.5 9.8 14.5 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Hamartin PF04388.12 CDJ51689.1 - 0.52 8.9 15.7 0.6 8.7 15.7 1.1 1 0 0 1 1 1 0 Hamartin protein Rrn6 PF10214.9 CDJ51689.1 - 0.63 8.5 20.4 0.65 8.4 20.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FAM60A PF15396.6 CDJ51689.1 - 0.65 10.0 14.4 1.2 9.1 14.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Band_3_cyto PF07565.13 CDJ51689.1 - 0.68 9.7 16.1 0.95 9.2 16.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MMR1 PF08505.10 CDJ51689.1 - 0.82 9.9 20.9 1.2 9.3 20.9 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF5523 PF17661.1 CDJ51689.1 - 0.87 9.2 21.8 1.3 8.7 21.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) SpoIIP PF07454.11 CDJ51689.1 - 1 8.8 23.4 1.5 8.2 23.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ51689.1 - 1.1 8.1 24.7 1.5 7.7 24.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MDM31_MDM32 PF08118.11 CDJ51689.1 - 1.5 7.4 10.6 2.6 6.6 10.6 1.5 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins LMBR1 PF04791.16 CDJ51689.1 - 1.6 7.5 6.7 1.7 7.4 6.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SLC12 PF03522.15 CDJ51689.1 - 2.2 7.2 19.8 2.9 6.8 19.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ51689.1 - 2.4 7.6 23.8 3.7 7.0 23.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 CDJ51689.1 - 2.7 6.2 19.3 4.3 5.5 19.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Ureide_permease PF07168.11 CDJ51689.1 - 4 6.1 10.0 8.8 5.0 10.0 1.6 1 0 0 1 1 1 0 Ureide permease Paramyxo_ncap PF00973.19 CDJ51689.1 - 5.1 5.9 14.0 6.6 5.5 14.0 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1980 PF09323.10 CDJ51689.1 - 6.6 6.6 14.9 13 5.7 14.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CSG2 PF16965.5 CDJ51689.1 - 6.8 5.5 12.9 8.7 5.2 12.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator TERB2 PF15101.6 CDJ51689.1 - 6.9 6.7 29.1 11 5.9 29.1 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 F-protein PF00469.20 CDJ51689.1 - 7.5 6.1 19.7 11 5.5 19.7 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef CAF1 PF04857.20 CDJ51689.1 - 8.1 5.5 12.4 11 5.1 12.4 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease NPR3 PF03666.13 CDJ51689.1 - 8.6 5.0 19.5 12 4.5 19.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 CDJ51689.1 - 9.1 4.3 19.3 12 3.8 19.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spore_coat_CotO PF14153.6 CDJ51690.1 - 0.015 15.2 27.2 0.016 15.1 27.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SLC12 PF03522.15 CDJ51690.1 - 0.63 9.0 21.9 0.66 8.9 21.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 CDJ51690.1 - 0.87 8.3 21.2 0.86 8.3 21.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 CDJ51690.1 - 1.4 7.6 29.0 1.4 7.6 29.0 1.2 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ51690.1 - 2 8.3 24.3 2.6 8.0 24.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF5427 PF10310.9 CDJ51690.1 - 2.5 7.0 30.5 3.3 6.6 30.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) LAP1C PF05609.12 CDJ51690.1 - 3.1 6.8 22.1 4.1 6.4 22.1 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Asp-B-Hydro_N PF05279.11 CDJ51690.1 - 3.2 7.8 33.6 3.8 7.5 33.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mitofilin PF09731.9 CDJ51690.1 - 3.9 6.2 32.8 4.4 6.0 32.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF936 PF06075.12 CDJ51690.1 - 6.2 5.6 24.3 7.5 5.3 24.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) XRN_M PF17846.1 CDJ51690.1 - 6.7 5.5 24.8 7.9 5.3 24.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Hid1 PF12722.7 CDJ51690.1 - 7 4.7 23.9 7.5 4.6 23.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RVT_1 PF00078.27 CDJ51691.1 - 1.2e-18 67.4 0.0 1.9e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDJ51691.1 - 1.3e-07 32.1 0.0 2.8e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ51691.1 - 8.4e-07 29.5 0.0 2.9e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 CDJ51691.1 - 2.4e-06 27.4 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 CDJ51692.1 - 7.9e-16 58.3 0.2 2.1e-15 56.9 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ51692.1 - 1.7e-15 57.3 0.1 3.3e-15 56.3 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 CDJ51692.1 - 9.1e-08 32.1 0.0 2.7e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ51692.1 - 0.052 13.4 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like IQ PF00612.27 CDJ51693.1 - 2.2e-14 51.8 22.4 0.00019 20.9 0.6 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif SOG2 PF10428.9 CDJ51693.1 - 1.6 7.9 28.8 2.1 7.4 28.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Gti1_Pac2 PF09729.9 CDJ51696.1 - 0.089 12.9 4.2 0.093 12.8 4.2 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family MarC PF01914.17 CDJ51696.1 - 0.09 12.1 0.2 0.096 12.1 0.2 1.1 1 0 0 1 1 1 0 MarC family integral membrane protein Sin_N PF04801.13 CDJ51696.1 - 0.2 10.8 14.9 0.22 10.7 14.9 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region CLN3 PF02487.17 CDJ51696.1 - 0.61 9.1 2.0 0.57 9.2 2.0 1.1 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 CDJ51696.1 - 2.1 7.0 7.7 2.3 6.9 7.7 1.1 1 0 0 1 1 1 0 Presenilin MscS_TM PF12794.7 CDJ51696.1 - 4.7 6.0 6.4 4.1 6.2 6.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 TFIIA PF03153.13 CDJ51696.1 - 7.8 6.4 27.2 9.1 6.1 27.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EMC3_TMCO1 PF01956.16 CDJ51696.1 - 9.9 5.9 7.9 9.6 5.9 7.9 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like UPRTase PF14681.6 CDJ51697.1 - 3e-08 33.4 0.4 4.3e-08 32.9 0.4 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Dehydrin PF00257.19 CDJ51698.1 - 0.00047 20.7 3.7 0.00047 20.7 3.7 4.1 4 1 1 5 5 5 1 Dehydrin DUF2722 PF10846.8 CDJ51698.1 - 0.0005 19.1 10.4 0.00056 19.0 3.5 2.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ51698.1 - 0.00092 19.9 11.1 0.016 15.9 8.2 3.9 3 1 0 3 3 3 2 Peroxisomal membrane anchor protein (Pex14p) conserved region EPL1 PF10513.9 CDJ51698.1 - 0.11 12.9 2.2 5.8 7.3 0.7 2.9 3 0 0 3 3 3 0 Enhancer of polycomb-like SUIM_assoc PF16619.5 CDJ51698.1 - 0.3 11.2 0.1 0.3 11.2 0.1 4.1 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ51698.1 - 0.86 9.2 21.6 0.45 10.1 4.7 3.0 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein BatD PF13584.6 CDJ51698.1 - 1.3 7.7 12.2 0.75 8.5 0.1 3.5 2 1 2 4 4 4 0 Oxygen tolerance Suf PF05843.14 CDJ51698.1 - 1.5 8.7 10.9 2.5 8.0 6.2 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Baculo_PP31 PF05311.11 CDJ51698.1 - 3 7.3 4.7 9.4 5.6 2.2 2.3 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DUF4834 PF16118.5 CDJ51698.1 - 7.5 7.6 13.5 8.6 7.4 3.9 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DnaJ PF00226.31 CDJ51699.1 - 0.0013 18.8 0.0 0.0039 17.3 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain SUIM_assoc PF16619.5 CDJ51699.1 - 0.0014 18.7 2.9 0.0014 18.7 2.9 12.9 9 3 1 10 10 10 4 Unstructured region C-term to UIM in Ataxin3 NAM-associated PF14303.6 CDJ51699.1 - 0.66 10.7 0.0 0.66 10.7 0.0 9.0 3 2 4 7 7 7 0 No apical meristem-associated C-terminal domain Spt4 PF06093.13 CDJ51700.1 - 8e-16 57.9 4.4 1.1e-09 38.2 0.5 3.2 2 1 1 3 3 3 2 Spt4/RpoE2 zinc finger zf_Rg PF17915.1 CDJ51700.1 - 0.00058 19.2 0.1 0.58 9.6 0.0 2.5 2 0 0 2 2 2 2 Reverse gyrase zinc finger zf-ribbon_3 PF13248.6 CDJ51700.1 - 0.0037 16.6 1.0 1.2 8.7 0.1 2.5 2 0 0 2 2 2 2 zinc-ribbon domain VP_N-CPKC PF11475.8 CDJ51700.1 - 0.057 13.3 0.7 16 5.5 0.1 2.7 2 0 0 2 2 2 0 Virion protein N terminal domain DUF3716 PF12511.8 CDJ51700.1 - 0.14 12.3 3.0 1.7 8.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Methyltransf_13 PF08421.11 CDJ51700.1 - 0.85 9.9 5.2 2.3 8.5 0.4 3.0 2 1 1 3 3 3 0 Putative zinc binding domain DUF4641 PF15483.6 CDJ51700.1 - 1.1 8.3 5.8 5.3 6.0 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4641) RskA PF10099.9 CDJ51701.1 - 0.014 15.7 17.1 0.014 15.7 17.1 5.2 2 2 2 4 4 4 0 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ51702.1 - 0.00024 20.2 4.1 0.00028 20.0 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ51702.1 - 0.031 14.3 20.0 0.038 14.0 20.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIEZO PF15917.5 CDJ51702.1 - 0.12 11.8 5.0 0.15 11.5 5.0 1.1 1 0 0 1 1 1 0 Piezo Eapp_C PF10238.9 CDJ51702.1 - 0.19 11.8 3.7 0.26 11.3 3.7 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Hydin_ADK PF17213.3 CDJ51702.1 - 0.27 11.5 9.4 0.38 11.0 9.4 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Spt20 PF12090.8 CDJ51702.1 - 0.34 10.5 18.4 0.46 10.1 18.4 1.1 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ51702.1 - 0.53 11.3 3.8 0.79 10.7 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) eIF-3_zeta PF05091.12 CDJ51702.1 - 2 7.3 7.6 2.3 7.1 7.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ51702.1 - 3.8 7.5 8.1 4.9 7.1 8.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 GREB1 PF15782.5 CDJ51702.1 - 3.9 4.5 9.3 4.9 4.1 9.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BAF1_ABF1 PF04684.13 CDJ51702.1 - 4.3 6.3 8.7 5.2 6.0 8.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Roughex PF06020.11 CDJ51702.1 - 6.1 5.8 10.6 7.8 5.5 10.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Nop53 PF07767.11 CDJ51702.1 - 8.9 5.6 17.2 13 5.0 17.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2722 PF10846.8 CDJ51703.1 - 0.01 14.8 10.8 0.01 14.8 10.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2722) FAM60A PF15396.6 CDJ51703.1 - 0.98 9.4 34.3 2.8 7.9 22.9 2.3 2 0 0 2 2 2 0 Protein Family FAM60A TCP PF03634.13 CDJ51703.1 - 1.5 9.4 49.0 4.7 7.8 30.9 2.5 2 0 0 2 2 2 0 TCP family transcription factor SR-25 PF10500.9 CDJ51703.1 - 1.6 8.3 64.2 0.97 9.0 6.7 2.7 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein DUF5523 PF17661.1 CDJ51703.1 - 5.8 6.5 32.2 0.57 9.8 2.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Nop16 PF09420.10 CDJ51704.1 - 1.1e-05 25.5 23.4 2.2e-05 24.6 5.6 2.9 1 1 2 3 3 3 2 Ribosome biogenesis protein Nop16 Activator_LAG-3 PF11498.8 CDJ51704.1 - 7.1 5.5 25.9 7.3 5.4 25.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RRM_1 PF00076.22 CDJ51705.1 - 2.3e-10 40.1 0.1 6.5e-10 38.7 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 CDJ51705.1 - 0.00055 20.1 27.1 0.00074 19.6 27.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ51705.1 - 0.012 15.3 12.4 0.012 15.2 12.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit RR_TM4-6 PF06459.12 CDJ51705.1 - 0.16 11.8 11.3 0.25 11.1 11.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.10 CDJ51705.1 - 0.2 10.3 13.8 0.23 10.1 13.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 CDJ51705.1 - 0.26 10.5 1.4 0.29 10.3 1.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FTZ PF03867.14 CDJ51705.1 - 0.27 10.7 9.7 0.5 9.9 9.7 1.4 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region SID-1_RNA_chan PF13965.6 CDJ51705.1 - 0.32 9.4 2.4 0.36 9.2 2.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ51705.1 - 0.43 10.6 7.1 0.6 10.1 7.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ51705.1 - 0.56 10.2 15.6 0.77 9.7 15.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) XRN_M PF17846.1 CDJ51705.1 - 0.57 9.1 11.5 0.77 8.6 11.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain V_ATPase_I PF01496.19 CDJ51705.1 - 0.93 7.3 15.2 1.2 7.0 15.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3332 PF11810.8 CDJ51705.1 - 1.3 8.6 7.8 2.3 7.8 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Ureide_permease PF07168.11 CDJ51705.1 - 2.1 7.0 3.5 2.6 6.7 3.5 1.3 1 0 0 1 1 1 0 Ureide permease Cu_amine_oxid PF01179.20 CDJ51705.1 - 2.3 7.1 8.9 3 6.7 8.9 1.1 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain SpoVR PF04293.13 CDJ51705.1 - 2.6 6.6 18.4 3.6 6.2 18.4 1.1 1 0 0 1 1 1 0 SpoVR like protein DUF4175 PF13779.6 CDJ51705.1 - 2.8 5.8 33.2 3.5 5.4 33.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SLC12 PF03522.15 CDJ51705.1 - 4.1 6.3 16.0 5.6 5.9 16.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CDJ51705.1 - 7.4 3.5 14.0 9.1 3.3 14.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ51705.1 - 8.7 4.5 27.3 12 4.1 27.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 CDJ51707.1 - 0.0029 17.7 16.3 0.0029 17.7 16.3 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ51707.1 - 0.0034 16.4 22.8 0.0035 16.3 7.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ51707.1 - 0.0059 16.6 3.0 0.0059 16.6 3.0 3.6 2 1 1 3 3 1 1 Unstructured region C-term to UIM in Ataxin3 Velvet PF11754.8 CDJ51707.1 - 0.096 12.6 11.4 0.49 10.3 4.2 2.3 2 1 0 2 2 2 0 Velvet factor PUB PF09409.10 CDJ51707.1 - 0.11 12.4 0.0 1.2 9.2 0.0 2.2 1 1 0 1 1 1 0 PUB domain Spt20 PF12090.8 CDJ51707.1 - 0.16 11.6 42.1 0.43 10.1 27.3 2.2 2 0 0 2 2 2 0 Spt20 family Suf PF05843.14 CDJ51707.1 - 0.23 11.4 16.4 0.024 14.6 5.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Eapp_C PF10238.9 CDJ51707.1 - 0.35 10.9 6.9 1.5 8.9 0.9 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF3843 PF12954.7 CDJ51707.1 - 0.53 9.2 3.4 2.4 7.0 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3843) BEX PF04538.12 CDJ51707.1 - 0.79 10.3 0.1 0.79 10.3 0.1 3.7 3 2 0 3 3 1 0 Brain expressed X-linked like family Hamartin PF04388.12 CDJ51707.1 - 1.4 7.5 11.3 1.4 7.5 4.4 2.0 2 0 0 2 2 2 0 Hamartin protein DUF719 PF05334.13 CDJ51707.1 - 2 8.6 8.4 2.4 8.3 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF4820 PF16091.5 CDJ51707.1 - 3.2 7.1 8.7 3.6 6.9 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Tristanin_u2 PF16638.5 CDJ51707.1 - 4.6 8.1 15.3 0.48 11.2 1.3 2.6 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers Roughex PF06020.11 CDJ51707.1 - 5.4 6.0 21.4 2.1 7.4 9.4 2.2 2 0 0 2 2 2 0 Drosophila roughex protein Connexin PF00029.19 CDJ51707.1 - 5.8 6.6 4.9 24 4.6 0.7 2.2 2 0 0 2 2 2 0 Connexin Pex14_N PF04695.13 CDJ51707.1 - 7.1 7.3 31.2 1 10.0 18.7 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 CDJ51707.1 - 7.7 6.5 15.7 7.7 6.5 6.6 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF3464 PF11947.8 CDJ51707.1 - 8.4 6.1 13.1 4.5 7.0 5.5 2.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 UPF0560 PF10577.9 CDJ51707.1 - 8.5 4.7 16.8 0.62 8.5 6.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 PI3K_1B_p101 PF10486.9 CDJ51709.1 - 0.13 10.0 6.4 0.15 9.8 6.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BRF1 PF07741.13 CDJ51709.1 - 0.17 12.2 5.1 0.19 12.1 5.1 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Lin-8 PF03353.15 CDJ51709.1 - 0.56 9.7 11.9 0.56 9.7 11.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist EIIBC-GUT_N PF03612.14 CDJ51709.1 - 0.73 9.6 6.1 0.73 9.5 6.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4175 PF13779.6 CDJ51709.1 - 1.2 6.9 18.6 1 7.2 18.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2722 PF10846.8 CDJ51709.1 - 1.8 7.4 20.8 1.9 7.3 20.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Connexin PF00029.19 CDJ51709.1 - 2.4 7.8 4.4 2.4 7.9 4.4 1.1 1 0 0 1 1 1 0 Connexin Chorion_2 PF03964.15 CDJ51709.1 - 2.8 8.8 14.1 4.2 8.3 14.1 1.4 1 1 0 1 1 1 0 Chorion family 2 TFIIA PF03153.13 CDJ51709.1 - 3.2 7.7 25.1 3.1 7.7 25.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Orf78 PF06024.12 CDJ51709.1 - 3.8 7.8 5.5 5.7 7.3 5.5 1.2 1 0 0 1 1 1 0 Orf78 (ac78) TERB2 PF15101.6 CDJ51709.1 - 3.9 7.5 11.8 3.7 7.5 11.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 CDJ51709.1 - 4.1 6.1 10.1 3.9 6.1 10.1 1.1 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.8 CDJ51709.1 - 6.9 6.4 8.9 8.7 6.1 8.9 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RCC1 PF00415.18 CDJ51710.1 - 4.7e-09 36.7 0.5 0.059 14.0 0.0 4.4 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Sin_N PF04801.13 CDJ51710.1 - 0.00032 20.0 17.8 0.00032 20.0 17.8 5.7 4 1 0 4 4 4 1 Sin-like protein conserved region SpoIIIAH PF12685.7 CDJ51710.1 - 0.00049 20.0 0.7 0.00049 20.0 0.7 6.0 5 1 1 6 6 6 2 SpoIIIAH-like protein EPL1 PF10513.9 CDJ51710.1 - 0.00096 19.6 7.6 0.00096 19.6 7.6 6.6 4 1 1 5 5 5 2 Enhancer of polycomb-like DDHD PF02862.17 CDJ51710.1 - 0.0018 18.5 4.0 0.0018 18.5 4.0 6.5 5 1 0 6 6 6 2 DDHD domain DUF5308 PF17233.2 CDJ51710.1 - 0.0027 17.9 3.2 0.0027 17.9 3.2 7.4 5 1 1 7 7 7 2 Family of unknown function (DUF5308) Pex14_N PF04695.13 CDJ51710.1 - 0.01 16.5 19.0 0.01 16.5 19.0 8.5 5 1 0 5 5 5 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Otopetrin PF03189.13 CDJ51710.1 - 3.7 6.3 23.2 0.26 10.1 11.4 3.5 2 1 0 2 2 2 0 Otopetrin Pkinase PF00069.25 CDJ51711.1 - 1.7e-08 34.2 0.0 1.7e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ51711.1 - 3.6e-06 26.4 0.0 7.6e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_C2 PF00648.21 CDJ51711.1 - 6.7e-06 25.3 0.0 1.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease DUF2722 PF10846.8 CDJ51711.1 - 0.0017 17.4 8.3 0.0017 17.4 8.3 6.9 7 0 0 7 7 7 4 Protein of unknown function (DUF2722) LRR_4 PF12799.7 CDJ51711.1 - 0.11 12.9 2.6 7.9 7.1 0.1 3.9 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ51711.1 - 3.3 8.0 5.1 18 5.7 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat HC2 PF07382.11 CDJ51712.1 - 6.6e-06 26.3 20.9 1.4e-05 25.3 20.9 1.6 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Abhydrolase_9_N PF15420.6 CDJ51713.1 - 9 6.2 6.8 16 5.4 0.3 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus SUIM_assoc PF16619.5 CDJ51714.1 - 0.22 11.6 13.8 0.47 10.5 13.8 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4366 PF14283.6 CDJ51715.1 - 0.79 9.8 6.5 0.96 9.5 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 CDJ51715.1 - 2.9 6.6 5.8 3 6.5 5.8 1.0 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 CDJ51715.1 - 3.8 6.8 17.0 4.5 6.6 17.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIF_alpha PF05793.12 CDJ51715.1 - 4.4 5.8 8.0 5 5.6 8.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rtf2 PF04641.12 CDJ51715.1 - 5.3 6.3 8.9 6.3 6.1 8.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF5521 PF17659.1 CDJ51715.1 - 6 4.6 5.8 6.4 4.5 5.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) SR-25 PF10500.9 CDJ51716.1 - 0.00068 19.3 12.2 0.002 17.8 7.6 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CDK2AP PF09806.9 CDJ51716.1 - 0.0062 16.6 10.5 0.37 10.8 0.5 2.1 2 0 0 2 2 2 2 Cyclin-dependent kinase 2-associated protein Velvet PF11754.8 CDJ51716.1 - 0.011 15.7 3.9 0.014 15.3 3.9 1.1 1 0 0 1 1 1 0 Velvet factor Spt20 PF12090.8 CDJ51716.1 - 0.017 14.8 1.3 0.017 14.8 1.3 2.1 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 CDJ51716.1 - 0.018 15.1 3.7 0.018 15.1 3.7 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Sin_N PF04801.13 CDJ51716.1 - 0.02 14.2 7.6 0.025 13.8 7.6 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF2722 PF10846.8 CDJ51716.1 - 0.02 13.9 15.8 0.061 12.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) N1221 PF07923.13 CDJ51716.1 - 0.024 13.8 0.8 0.82 8.8 0.1 2.1 2 0 0 2 2 2 0 N1221-like protein RRN3 PF05327.11 CDJ51716.1 - 0.031 12.8 3.5 0.039 12.5 3.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AUX_IAA PF02309.16 CDJ51716.1 - 0.062 13.2 1.0 0.094 12.6 1.0 1.3 1 0 0 1 1 1 0 AUX/IAA family DUF5345 PF17280.2 CDJ51716.1 - 0.067 13.2 9.1 1.9 8.5 0.5 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5345) DUF1129 PF06570.11 CDJ51716.1 - 0.09 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4820 PF16091.5 CDJ51716.1 - 0.13 11.6 5.5 0.059 12.7 3.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) Orf78 PF06024.12 CDJ51716.1 - 0.19 12.0 0.4 10 6.5 0.1 2.3 2 0 0 2 2 2 0 Orf78 (ac78) DUF4407 PF14362.6 CDJ51716.1 - 0.35 10.2 4.9 0.49 9.7 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Caudo_TAP PF02413.17 CDJ51716.1 - 0.75 9.9 10.7 0.37 10.9 2.8 2.1 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK TCP PF03634.13 CDJ51716.1 - 1.5 9.4 10.8 3.9 8.0 5.8 2.1 2 0 0 2 2 2 0 TCP family transcription factor FTZ PF03867.14 CDJ51716.1 - 1.7 8.1 9.1 1.4 8.4 0.5 2.1 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region CCDC53 PF10152.9 CDJ51716.1 - 1.8 9.0 8.2 6.4 7.2 0.3 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex IMUP PF15761.5 CDJ51716.1 - 1.9 9.2 13.1 0.3 11.8 8.1 1.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein Androgen_recep PF02166.16 CDJ51716.1 - 2 7.2 22.4 0.47 9.2 6.9 2.2 2 0 0 2 2 2 0 Androgen receptor ORC_WH_C PF18137.1 CDJ51716.1 - 3.2 7.8 7.6 6.4 6.9 2.9 2.1 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Roughex PF06020.11 CDJ51716.1 - 9.2 5.3 15.6 3.5 6.6 5.0 2.1 2 0 0 2 2 2 0 Drosophila roughex protein DUF4179 PF13786.6 CDJ51718.1 - 0.13 12.8 1.2 1.7 9.1 0.2 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Nucleoporin_FG PF13634.6 CDJ51720.1 - 1.5e-38 131.5 276.3 5.4e-10 40.0 38.2 9.4 2 2 7 9 9 9 9 Nucleoporin FG repeat region Polyoma_coat2 PF00761.20 CDJ51720.1 - 0.58 9.8 6.0 1.2 8.8 6.0 1.5 1 0 0 1 1 1 0 Polyomavirus coat protein DNA_topoisoIV PF00521.20 CDJ51722.1 - 6.1e-119 397.7 0.0 8.4e-119 397.2 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CDJ51722.1 - 1.6e-23 83.4 0.6 8.2e-17 61.7 0.1 3.0 1 1 1 2 2 2 2 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CDJ51722.1 - 1.6e-19 70.1 1.1 3.2e-19 69.1 1.1 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CDJ51722.1 - 1.2e-10 41.9 0.1 4.6e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CDJ51722.1 - 2.4e-07 30.9 0.0 6.6e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Ribosomal_S27 PF01599.19 CDJ51723.1 - 3.2e-26 91.2 2.3 5.8e-26 90.4 2.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 CDJ51723.1 - 1.2e-12 47.4 0.1 2.4e-12 46.4 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ51723.1 - 0.00049 19.9 0.1 0.0017 18.1 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDJ51723.1 - 0.0048 16.9 0.4 0.018 15.0 0.0 2.1 3 1 0 3 3 3 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CDJ51723.1 - 0.008 16.6 0.0 0.068 13.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-like domain IBR PF01485.21 CDJ51723.1 - 0.052 13.8 1.3 0.088 13.0 1.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Wound_ind PF08186.11 CDJ51723.1 - 0.38 11.2 2.7 0.57 10.6 1.7 1.8 2 0 0 2 2 2 0 Wound-inducible basic protein family EF_TS PF00889.19 CDJ51724.1 - 2.1e-24 86.3 0.0 2.2e-23 83.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor TS TAP_C PF03943.13 CDJ51724.1 - 0.032 13.8 0.2 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 TAP C-terminal domain UBA_4 PF14555.6 CDJ51724.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain UBA PF00627.31 CDJ51724.1 - 0.088 12.7 0.1 0.24 11.4 0.1 1.8 1 0 0 1 1 1 0 UBA/TS-N domain Pkinase PF00069.25 CDJ51726.1 - 7.8e-41 140.2 0.0 1.5e-32 113.0 0.0 4.3 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ51726.1 - 4.6e-16 58.9 0.0 7.1e-15 55.0 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ51726.1 - 0.00027 20.0 0.1 0.0006 18.9 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CDJ51726.1 - 0.0093 15.9 2.6 0.0093 15.9 2.6 3.6 3 1 1 4 4 4 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CDJ51726.1 - 0.28 10.1 0.1 0.41 9.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 CDJ51726.1 - 8.6 5.0 21.2 3.2 6.4 15.4 2.8 2 1 0 2 2 2 0 Fungal protein kinase Sec23_trunk PF04811.15 CDJ51727.1 - 1.2e-53 182.2 0.0 2.4e-49 168.1 0.0 2.2 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CDJ51727.1 - 2.2e-16 60.4 0.0 4.1e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CDJ51727.1 - 1.2e-14 54.1 3.8 2e-14 53.3 3.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 CDJ51727.1 - 3.2e-10 39.7 0.0 7.9e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 CDJ51727.1 - 5.3e-05 23.0 0.0 0.00026 20.8 0.0 2.2 1 0 0 1 1 1 1 Gelsolin repeat MRNIP PF15749.5 CDJ51727.1 - 0.62 10.8 0.1 0.62 10.8 0.1 2.6 2 1 0 2 2 2 0 MRN-interacting protein US6 PF17616.2 CDJ51729.1 - 0.21 11.5 0.8 0.29 11.0 0.8 1.2 1 0 0 1 1 1 0 Viral unique short region 6 Takusan PF04822.13 CDJ51730.1 - 0.025 14.5 0.8 0.025 14.5 0.8 2.0 2 0 0 2 2 2 0 Takusan UPF0524 PF15823.5 CDJ51730.1 - 0.084 12.3 1.9 0.17 11.3 1.9 1.4 1 0 0 1 1 1 0 UPF0524 of C3orf70 BRE PF06113.12 CDJ51732.1 - 0.019 13.8 0.6 0.036 12.9 0.6 1.4 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) FlaC_arch PF05377.11 CDJ51732.1 - 0.45 10.9 2.7 4.3 7.8 0.0 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) KASH PF10541.9 CDJ51732.1 - 2 8.8 9.8 0.96 9.8 2.0 2.5 2 0 0 2 2 2 0 Nuclear envelope localisation domain EphA2_TM PF14575.6 CDJ51733.1 - 0.04 14.8 0.3 4.2 8.3 0.1 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain SUIM_assoc PF16619.5 CDJ51733.1 - 0.27 11.3 31.7 0.16 12.0 7.8 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ51733.1 - 0.28 10.7 26.7 0.57 9.8 8.9 2.4 3 0 0 3 3 3 0 Spt20 family DUF2722 PF10846.8 CDJ51733.1 - 0.55 9.1 20.8 0.83 8.5 5.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) DUF3371 PF11851.8 CDJ51733.1 - 0.8 10.8 11.2 2.7 9.1 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) ANAPC_CDC26 PF10471.9 CDJ51733.1 - 4.6 8.1 28.5 1.8 9.4 6.8 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 PIG-U PF06728.13 CDJ51733.1 - 7.5 5.5 4.8 36 3.3 4.8 2.0 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U DUF1645 PF07816.11 CDJ51734.1 - 0.033 14.8 10.5 0.048 14.2 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DUF4482 PF14818.6 CDJ51734.1 - 0.033 15.0 9.4 0.041 14.7 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) CCDC106 PF15794.5 CDJ51734.1 - 0.068 12.9 11.7 0.09 12.5 11.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Macoilin PF09726.9 CDJ51734.1 - 0.57 8.7 10.9 0.62 8.6 10.9 1.0 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 CDJ51734.1 - 0.73 8.7 7.8 0.83 8.6 7.8 1.0 1 0 0 1 1 1 0 Mitoguardin Allexi_40kDa PF05549.11 CDJ51734.1 - 0.86 9.1 5.0 1.1 8.6 5.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein SR-25 PF10500.9 CDJ51734.1 - 0.95 9.0 27.3 0.66 9.5 25.7 1.5 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein LAGLIDADG_3 PF14528.6 CDJ51734.1 - 1.7 9.0 5.5 3 8.2 0.4 2.3 2 0 0 2 2 2 0 LAGLIDADG-like domain PAP1 PF08601.10 CDJ51734.1 - 2.9 7.5 10.3 3.5 7.3 10.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 GREB1 PF15782.5 CDJ51734.1 - 4.6 4.2 9.1 4.8 4.2 9.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ctr PF04145.15 CDJ51735.1 - 0.012 16.2 3.2 0.012 16.2 3.2 6.8 4 2 0 5 5 5 0 Ctr copper transporter family DUF1645 PF07816.11 CDJ51736.1 - 0.029 15.0 9.7 0.033 14.8 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) FAA_hydrolase_N PF09298.11 CDJ51736.1 - 0.15 12.2 6.3 0.27 11.5 6.3 1.4 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal DOCK_N PF16172.5 CDJ51736.1 - 0.17 10.8 7.8 0.19 10.6 7.8 1.1 1 0 0 1 1 1 0 DOCK N-terminus Lin-8 PF03353.15 CDJ51736.1 - 0.21 11.1 14.1 0.29 10.7 14.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PA26 PF04636.13 CDJ51736.1 - 0.51 9.2 9.9 0.54 9.1 9.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Peptidase_S15 PF02129.18 CDJ51736.1 - 0.54 9.8 11.9 0.7 9.4 11.9 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) IHABP4_N PF16174.5 CDJ51736.1 - 1.2 9.7 21.8 1.7 9.2 21.8 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal HemX PF04375.14 CDJ51736.1 - 1.4 8.1 30.0 1.7 7.8 30.0 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Presenilin PF01080.17 CDJ51736.1 - 3 6.5 15.3 3.4 6.3 15.3 1.1 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ51736.1 - 3.1 7.3 27.2 15 5.1 27.4 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.9 CDJ51736.1 - 3.8 5.7 21.0 3.7 5.7 21.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ51736.1 - 4.9 6.9 10.7 5.8 6.7 10.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ51736.1 - 5 6.0 12.3 5.8 5.8 12.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RskA PF10099.9 CDJ51736.1 - 10 6.4 42.4 1.5 9.1 7.6 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA RAP1 PF07218.11 CDJ51737.1 - 0.54 8.5 10.2 0.65 8.2 10.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Virul_Fac PF10139.9 CDJ51737.1 - 0.63 8.2 5.8 0.95 7.6 5.8 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor SR-25 PF10500.9 CDJ51738.1 - 0.0019 17.8 26.7 0.0023 17.6 26.7 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.13 CDJ51738.1 - 1.1 8.3 25.7 1.2 8.1 25.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PP1_bind PF15276.6 CDJ51738.1 - 1.5 9.1 15.5 2.8 8.3 5.5 2.3 2 0 0 2 2 2 0 Protein phosphatase 1 binding DUF2052 PF09747.9 CDJ51738.1 - 6.5 6.8 26.9 9.2 6.3 26.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Prenyltransf PF01255.19 CDJ51739.1 - 9.8e-25 87.4 1.1 1.2e-24 87.1 1.1 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase TERB2 PF15101.6 CDJ51739.1 - 0.00017 21.8 15.4 0.00021 21.4 15.4 1.1 1 0 0 1 1 1 1 Telomere-associated protein TERB2 MLANA PF14991.6 CDJ51739.1 - 0.0048 17.2 3.3 0.0078 16.5 3.3 1.3 1 0 0 1 1 1 1 Protein melan-A MMR1 PF08505.10 CDJ51739.1 - 0.007 16.7 14.8 0.0088 16.4 14.8 1.1 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 CDJ51739.1 - 0.008 16.2 32.9 0.0086 16.1 32.9 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Thg1C PF14413.6 CDJ51739.1 - 0.011 15.9 8.0 0.016 15.4 8.0 1.2 1 0 0 1 1 1 0 Thg1 C terminal domain RskA PF10099.9 CDJ51739.1 - 0.011 16.0 9.8 0.027 14.8 9.8 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SID-1_RNA_chan PF13965.6 CDJ51739.1 - 0.011 14.2 0.2 0.012 14.1 0.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 CDJ51739.1 - 0.014 16.3 12.5 0.014 16.3 12.5 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) CPSF100_C PF13299.6 CDJ51739.1 - 0.015 15.5 4.9 0.02 15.1 4.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.19 CDJ51739.1 - 0.016 13.2 5.4 0.016 13.1 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family tRNA-synt_2c PF01411.19 CDJ51739.1 - 0.028 12.9 2.0 0.035 12.6 2.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) DDHD PF02862.17 CDJ51739.1 - 0.038 14.2 7.6 0.045 13.9 7.6 1.1 1 0 0 1 1 1 0 DDHD domain CCDC53 PF10152.9 CDJ51739.1 - 0.038 14.4 10.9 0.064 13.7 10.9 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FPN1 PF06963.12 CDJ51739.1 - 0.044 12.3 2.3 0.061 11.9 2.3 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Spt20 PF12090.8 CDJ51739.1 - 0.061 12.9 41.6 0.09 12.4 41.6 1.2 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ51739.1 - 0.068 11.9 12.2 0.1 11.3 12.2 1.3 1 0 0 1 1 1 0 Presenilin Bac_luciferase PF00296.20 CDJ51739.1 - 0.077 12.4 3.8 0.11 11.9 3.8 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase Pex14_N PF04695.13 CDJ51739.1 - 0.077 13.6 20.2 0.15 12.7 20.2 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 CDJ51739.1 - 0.088 12.6 7.8 0.11 12.4 7.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 CDJ51739.1 - 0.092 12.1 14.9 0.12 11.7 14.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CBP_BcsG PF11658.8 CDJ51739.1 - 0.1 11.0 6.2 0.13 10.6 6.2 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG AAA_23 PF13476.6 CDJ51739.1 - 0.12 12.9 9.7 0.13 12.7 9.7 1.2 1 0 0 1 1 1 0 AAA domain SpoIIP PF07454.11 CDJ51739.1 - 0.13 11.7 11.1 0.16 11.4 11.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PepSY_TM PF03929.16 CDJ51739.1 - 0.15 11.7 6.0 0.21 11.2 6.0 1.4 1 0 0 1 1 1 0 PepSY-associated TM region FAM176 PF14851.6 CDJ51739.1 - 0.2 11.3 5.2 0.32 10.7 5.2 1.3 1 0 0 1 1 1 0 FAM176 family CLN3 PF02487.17 CDJ51739.1 - 0.2 10.7 6.8 0.27 10.2 6.8 1.2 1 0 0 1 1 1 0 CLN3 protein TFB6 PF17110.5 CDJ51739.1 - 0.21 11.3 6.2 0.34 10.6 6.2 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TMEM51 PF15345.6 CDJ51739.1 - 0.25 11.2 11.9 0.38 10.5 11.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 eIF-3_zeta PF05091.12 CDJ51739.1 - 0.27 10.2 17.6 0.33 9.9 17.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.6 CDJ51739.1 - 0.28 9.0 27.7 0.33 8.8 27.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_S49_N PF08496.10 CDJ51739.1 - 0.32 11.0 7.7 0.66 10.0 7.7 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EOS1 PF12326.8 CDJ51739.1 - 0.34 10.8 3.2 0.47 10.3 3.2 1.3 1 0 0 1 1 1 0 N-glycosylation protein EPL1 PF10513.9 CDJ51739.1 - 0.52 10.7 13.3 0.66 10.4 13.3 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Suf PF05843.14 CDJ51739.1 - 0.53 10.2 15.0 0.65 9.9 15.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ATAD4 PF15321.6 CDJ51739.1 - 0.56 11.6 7.3 0.8 11.1 7.3 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Rxt3 PF08642.10 CDJ51739.1 - 0.69 10.7 5.4 1 10.1 5.4 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Serinc PF03348.15 CDJ51739.1 - 0.78 8.6 6.3 1.2 8.0 6.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hid1 PF12722.7 CDJ51739.1 - 0.81 7.7 10.3 0.98 7.5 10.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 CDJ51739.1 - 0.89 8.5 11.2 1.1 8.2 11.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 CDJ51739.1 - 0.89 9.6 12.4 1.3 9.0 12.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2722 PF10846.8 CDJ51739.1 - 0.93 8.4 34.3 1.2 8.0 34.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PAT1 PF09770.9 CDJ51739.1 - 1 7.6 24.3 1.2 7.3 24.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EIIBC-GUT_N PF03612.14 CDJ51739.1 - 1 9.1 10.0 1.4 8.6 10.0 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus HCO3_cotransp PF00955.21 CDJ51739.1 - 1 8.1 2.3 1.3 7.7 2.3 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF775 PF05603.12 CDJ51739.1 - 1.1 8.8 12.1 1.6 8.2 12.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4518 PF15008.6 CDJ51739.1 - 1.2 8.3 13.3 1.7 7.8 13.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Roughex PF06020.11 CDJ51739.1 - 1.2 8.2 14.0 1.9 7.5 14.0 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Band_3_cyto PF07565.13 CDJ51739.1 - 1.2 8.9 12.8 1.8 8.3 12.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CSG2 PF16965.5 CDJ51739.1 - 1.2 8.0 5.0 1.8 7.4 5.0 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator O-antigen_lig PF13425.6 CDJ51739.1 - 1.4 7.6 3.0 2.1 7.0 3.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FAM60A PF15396.6 CDJ51739.1 - 1.6 8.7 10.5 2.2 8.2 10.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Pannexin_like PF12534.8 CDJ51739.1 - 1.8 7.6 9.7 2.5 7.1 9.7 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Hydin_ADK PF17213.3 CDJ51739.1 - 1.9 8.8 10.9 2.9 8.1 10.9 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Membralin PF09746.9 CDJ51739.1 - 1.9 7.5 7.3 2.4 7.1 7.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Otopetrin PF03189.13 CDJ51739.1 - 2 7.1 6.1 3.1 6.5 6.1 1.2 1 0 0 1 1 1 0 Otopetrin Paramyxo_ncap PF00973.19 CDJ51739.1 - 2.4 7.0 9.2 3 6.6 9.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Ndc1_Nup PF09531.10 CDJ51739.1 - 2.8 6.5 14.4 3.9 6.0 14.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec62 PF03839.16 CDJ51739.1 - 2.8 7.4 11.4 4.4 6.7 11.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Folate_carrier PF01770.18 CDJ51739.1 - 2.9 6.5 6.4 4.1 6.0 6.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier ALMT PF11744.8 CDJ51739.1 - 2.9 6.6 9.3 3.5 6.3 9.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Tim54 PF11711.8 CDJ51739.1 - 3.7 6.3 12.5 4.7 5.9 12.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ATP-synt_E PF05680.12 CDJ51739.1 - 4.4 7.7 13.2 0.16 12.3 7.4 1.6 2 0 0 2 2 1 0 ATP synthase E chain GREB1 PF15782.5 CDJ51739.1 - 4.4 4.3 15.2 5.1 4.1 15.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1980 PF09323.10 CDJ51739.1 - 4.5 7.1 8.4 7.1 6.5 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Baculo_PP31 PF05311.11 CDJ51739.1 - 5 6.5 13.4 6.3 6.2 13.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RabGAP-TBC PF00566.18 CDJ51739.1 - 5.8 6.5 12.9 8.9 5.9 12.9 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Coilin_N PF15862.5 CDJ51739.1 - 6.3 6.6 14.5 11 5.8 14.5 1.4 1 0 0 1 1 1 0 Coilin N-terminus Kei1 PF08552.11 CDJ51739.1 - 6.9 6.5 7.7 10 6.0 7.7 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 MDM10 PF12519.8 CDJ51739.1 - 7.3 5.3 12.2 9.8 4.9 12.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 TMEM208_SND2 PF05620.11 CDJ51739.1 - 7.5 6.3 9.8 15 5.3 9.8 1.6 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 AIF_C PF14721.6 CDJ51739.1 - 8.3 6.8 10.5 13 6.1 10.5 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PepSY_TM_like_2 PF16357.5 CDJ51739.1 - 8.8 6.2 9.5 14 5.6 0.1 2.2 2 0 0 2 2 2 0 Putative PepSY_TM-like UPF0524 PF15823.5 CDJ51739.1 - 9.1 5.6 9.2 13 5.1 9.2 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 NEMP PF10225.9 CDJ51739.1 - 9.6 5.8 7.5 0.78 9.4 3.1 1.4 2 0 0 2 2 1 0 NEMP family Pex14_N PF04695.13 CDJ51742.1 - 0.0039 17.9 8.5 0.0039 17.9 8.5 4.9 4 0 0 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.17 CDJ51742.1 - 0.021 15.0 0.2 0.021 15.0 0.2 3.4 2 1 0 2 2 2 0 DDHD domain Peroxin-3 PF04882.12 CDJ51742.1 - 0.032 13.3 0.1 0.032 13.3 0.1 3.2 3 0 0 3 3 3 0 Peroxin-3 Connexin PF00029.19 CDJ51742.1 - 0.91 9.2 14.3 1.8 8.3 3.2 3.2 3 0 0 3 3 3 0 Connexin MecA PF05389.12 CDJ51742.1 - 4.3 6.9 13.9 0.32 10.6 1.7 3.3 4 0 0 4 4 4 0 Negative regulator of genetic competence (MecA) SpoIIP PF07454.11 CDJ51742.1 - 4.6 6.6 23.1 0.11 11.9 4.5 3.1 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) CCDC84 PF14968.6 CDJ51743.1 - 0.03 13.9 1.4 0.05 13.2 1.4 1.4 1 0 0 1 1 1 0 Coiled coil protein 84 DUF2312 PF10073.9 CDJ51743.1 - 0.075 12.7 0.2 12 5.6 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Bep_C_terminal PF17841.1 CDJ51743.1 - 0.38 11.0 3.5 0.58 10.4 1.6 2.3 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) DUF1664 PF07889.12 CDJ51743.1 - 0.43 10.6 3.5 2.8 8.0 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Pox_Ag35 PF03286.14 CDJ51744.1 - 0.0014 18.5 7.0 0.0014 18.5 7.0 2.0 2 0 0 2 2 1 1 Pox virus Ag35 surface protein Presenilin PF01080.17 CDJ51744.1 - 0.0033 16.2 16.3 0.0033 16.2 16.3 1.8 2 0 0 2 2 2 1 Presenilin SID-1_RNA_chan PF13965.6 CDJ51744.1 - 0.0034 15.9 2.3 0.0051 15.3 2.3 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Zip PF02535.22 CDJ51744.1 - 0.0038 16.5 2.9 0.0072 15.6 2.9 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter DUF913 PF06025.12 CDJ51744.1 - 0.01 14.8 7.8 0.025 13.5 7.8 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CLN3 PF02487.17 CDJ51744.1 - 0.039 13.0 8.8 0.074 12.1 8.8 1.4 1 0 0 1 1 1 0 CLN3 protein Peptidase_S64 PF08192.11 CDJ51744.1 - 0.081 11.4 10.7 0.11 10.9 10.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 CDC45 PF02724.14 CDJ51744.1 - 0.18 10.1 21.6 0.0093 14.3 16.2 1.5 2 0 0 2 2 2 0 CDC45-like protein Smg8_Smg9 PF10220.9 CDJ51744.1 - 0.18 10.1 16.8 0.36 9.1 16.8 1.4 1 0 0 1 1 1 0 Smg8_Smg9 Bul1_N PF04425.12 CDJ51744.1 - 0.23 10.2 12.5 0.44 9.2 12.5 1.3 1 0 0 1 1 1 0 Bul1 N terminus PPP4R2 PF09184.11 CDJ51744.1 - 0.24 10.9 16.6 0.06 12.9 11.9 2.2 2 0 0 2 2 2 0 PPP4R2 DUF2828 PF11443.8 CDJ51744.1 - 0.27 9.3 16.7 0.53 8.3 16.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PA26 PF04636.13 CDJ51744.1 - 0.34 9.8 10.8 0.73 8.7 10.8 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Serinc PF03348.15 CDJ51744.1 - 0.47 9.3 12.0 0.11 11.4 7.7 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) ASC PF00858.24 CDJ51744.1 - 0.51 9.2 4.3 0.85 8.5 4.3 1.4 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF2370 PF10176.9 CDJ51744.1 - 0.57 9.8 5.9 1.3 8.6 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Hid1 PF12722.7 CDJ51744.1 - 0.79 7.8 16.0 1.7 6.7 16.0 1.5 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tim54 PF11711.8 CDJ51744.1 - 0.79 8.4 19.9 1.9 7.2 19.9 1.6 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 OATP PF03137.20 CDJ51744.1 - 1.3 7.2 4.9 2.4 6.4 4.9 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family eIF-3_zeta PF05091.12 CDJ51744.1 - 1.6 7.6 21.8 3.1 6.7 21.8 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EPL1 PF10513.9 CDJ51744.1 - 1.6 9.1 20.6 0.67 10.3 17.4 2.0 2 0 0 2 2 1 0 Enhancer of polycomb-like Sporozoite_P67 PF05642.11 CDJ51744.1 - 1.8 6.6 8.0 2.7 6.0 8.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SLC12 PF03522.15 CDJ51744.1 - 1.8 7.5 21.0 4 6.4 21.0 1.5 1 0 0 1 1 1 0 Solute carrier family 12 MMR1 PF08505.10 CDJ51744.1 - 2.1 8.6 22.2 0.15 12.3 16.4 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein ALMT PF11744.8 CDJ51744.1 - 3 6.6 22.3 0.9 8.3 16.0 2.5 2 0 0 2 2 2 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 CDJ51744.1 - 3.3 5.5 27.1 0.025 12.5 17.8 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1980 PF09323.10 CDJ51744.1 - 3.9 7.3 8.3 9 6.2 8.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) VIR_N PF15912.5 CDJ51744.1 - 4.8 6.7 17.9 11 5.5 17.9 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal Otopetrin PF03189.13 CDJ51744.1 - 4.9 5.9 7.4 8.8 5.0 7.4 1.4 1 0 0 1 1 1 0 Otopetrin SpoIIP PF07454.11 CDJ51744.1 - 5.2 6.5 24.4 11 5.3 24.4 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 CDJ51744.1 - 5.3 5.7 23.6 0.42 9.3 17.7 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Lin-8 PF03353.15 CDJ51744.1 - 7.4 6.0 26.2 0.51 9.9 20.7 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 CDJ51744.1 - 7.4 4.7 35.9 0.0095 14.3 24.0 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.13 CDJ51744.1 - 7.9 5.4 24.4 0.54 9.3 17.0 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor CKAP2_C PF15297.6 CDJ51744.1 - 8.1 5.4 27.8 2.8 6.9 0.1 2.8 3 0 0 3 3 3 0 Cytoskeleton-associated protein 2 C-terminus Cellulose_synt PF03552.14 CDJ51744.1 - 8.5 4.7 6.6 13 4.1 6.6 1.2 1 0 0 1 1 1 0 Cellulose synthase RR_TM4-6 PF06459.12 CDJ51744.1 - 9.5 5.9 34.9 0.39 10.5 25.2 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Pal1 PF08316.11 CDJ51744.1 - 9.6 7.0 7.8 26 5.6 7.8 1.7 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF2722 PF10846.8 CDJ51745.1 - 0.00071 18.6 9.1 0.00071 18.6 9.1 7.1 4 2 2 6 6 6 2 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ51745.1 - 0.0058 16.3 10.3 0.0058 16.3 10.3 5.5 5 0 0 5 5 5 3 Nuclear RNA-splicing-associated protein DUF2434 PF10361.9 CDJ51745.1 - 0.1 11.6 0.3 0.5 9.3 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) RAP1 PF07218.11 CDJ51745.1 - 9.5 4.4 5.7 19 3.4 5.7 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AP2 PF00847.20 CDJ51746.1 - 0.046 14.0 0.0 0.046 14.0 0.0 3.5 4 1 0 4 4 4 0 AP2 domain TrmB PF01978.19 CDJ51748.1 - 0.78 9.7 10.7 67 3.5 0.1 5.1 2 2 3 5 5 5 0 Sugar-specific transcriptional regulator TrmB MCPsignal PF00015.21 CDJ51748.1 - 0.95 9.2 13.7 0.056 13.3 5.2 3.3 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 CDJ51748.1 - 3.4 8.0 5.4 21 5.5 3.7 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PIH1 PF08190.12 CDJ51749.1 - 1.2e-17 63.8 0.0 2.6e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 PIH1 N-terminal domain zf-Tim10_DDP PF02953.15 CDJ51750.1 - 9.7e-15 54.0 7.6 2.9e-14 52.4 7.6 1.7 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 CDJ51750.1 - 0.018 14.8 3.5 0.031 14.0 3.5 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Tfb2 PF03849.14 CDJ51751.1 - 1.2e-05 24.5 1.5 1.8e-05 23.9 1.5 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 DUF2722 PF10846.8 CDJ51751.1 - 0.00049 19.2 6.0 0.00049 19.2 6.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF3682 PF12446.8 CDJ51751.1 - 0.0022 18.5 33.5 0.0022 18.5 33.5 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF3682) Mlh1_C PF16413.5 CDJ51751.1 - 0.011 15.1 0.3 0.021 14.2 0.3 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus DUF4667 PF15700.5 CDJ51751.1 - 0.017 15.2 15.9 0.41 10.7 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ51751.1 - 0.079 12.9 34.9 0.055 13.5 22.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ51751.1 - 1.1 9.3 4.3 1.4 8.9 0.6 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Activator_LAG-3 PF11498.8 CDJ51751.1 - 3.1 6.7 38.3 2.7 6.9 2.1 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ51751.1 - 6.4 6.3 35.9 1.3 8.6 3.7 2.1 2 0 0 2 2 2 0 Spt20 family Sporozoite_P67 PF05642.11 CDJ51751.1 - 6.4 4.7 19.1 24 2.8 19.1 1.8 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Shadoo PF14999.6 CDJ51752.1 - 0.0027 17.8 18.6 0.0098 16.0 1.1 2.2 2 0 0 2 2 2 2 Shadow of prion protein, neuroprotective Glyco_hydro_9 PF00759.19 CDJ51752.1 - 0.7 9.3 16.9 2.4 7.5 8.1 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 Ribosomal_60s PF00428.19 CDJ51752.1 - 0.83 10.3 31.9 0.45 11.1 7.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein TAF4 PF05236.14 CDJ51752.1 - 1.6 8.4 30.4 0.14 11.8 10.6 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family BAF1_ABF1 PF04684.13 CDJ51752.1 - 1.7 7.6 23.2 1.2 8.2 5.8 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor RNA_pol_Rpc4 PF05132.14 CDJ51752.1 - 8 6.9 18.6 5.7 7.4 6.5 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 ABC1 PF03109.16 CDJ51753.1 - 1e-29 103.1 0.0 1.9e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RskA PF10099.9 CDJ51753.1 - 0.0009 19.6 7.5 0.0009 19.6 7.5 10.8 8 2 2 11 11 11 3 Anti-sigma-K factor rskA SPX PF03105.19 CDJ51753.1 - 0.0011 19.0 3.9 0.0011 19.0 3.9 5.8 2 2 2 4 4 4 1 SPX domain SUIM_assoc PF16619.5 CDJ51753.1 - 0.0017 18.4 0.9 0.0017 18.4 0.9 9.7 9 1 0 9 9 9 2 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ51754.1 - 0.00016 21.4 7.3 0.00016 21.4 7.3 9.5 9 1 0 9 9 9 1 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ51754.1 - 0.0095 16.0 1.4 0.0095 16.0 1.4 15.7 14 3 0 14 14 14 3 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ51755.1 - 8.1e-06 25.1 4.3 8.1e-06 25.1 4.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Pex2_Pex12 PF04757.14 CDJ51755.1 - 1.6e-05 24.6 1.2 5e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region DUF5427 PF10310.9 CDJ51755.1 - 0.0045 16.0 7.6 0.0045 16.0 7.6 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5427) CDC45 PF02724.14 CDJ51755.1 - 0.012 14.0 0.7 0.016 13.6 0.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4518 PF15008.6 CDJ51755.1 - 0.018 14.3 0.5 0.027 13.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Pex14_N PF04695.13 CDJ51755.1 - 0.022 15.4 11.7 0.022 15.4 11.7 3.3 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apt1 PF10351.9 CDJ51755.1 - 0.055 12.3 1.1 0.1 11.4 1.1 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAPS PF04499.15 CDJ51755.1 - 0.11 11.2 1.3 0.17 10.6 1.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIP PF07454.11 CDJ51755.1 - 0.14 11.6 2.6 0.22 11.0 2.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ51755.1 - 0.23 10.4 9.1 0.39 9.6 9.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 CDJ51755.1 - 0.32 10.8 7.9 0.64 9.8 7.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 CDJ51755.1 - 0.67 9.9 12.6 0.052 13.5 6.4 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Connexin PF00029.19 CDJ51755.1 - 1.1 9.0 2.7 1.8 8.2 2.7 1.3 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ51755.1 - 4.5 5.9 13.6 1.1 7.9 9.8 1.9 2 0 0 2 2 2 0 Presenilin SR-25 PF10500.9 CDJ51755.1 - 4.6 6.8 22.5 0.025 14.2 2.6 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ51755.1 - 7.2 7.1 14.4 3.2 8.3 7.2 2.7 3 0 0 3 3 3 0 TCP family transcription factor PAP1 PF08601.10 CDJ51756.1 - 0.062 13.0 0.0 0.062 13.0 0.0 6.0 6 1 1 7 7 7 0 Transcription factor PAP1 Spore_YhcN_YlaJ PF09580.10 CDJ51756.1 - 0.17 11.9 9.9 5.5 7.1 5.5 2.9 2 1 1 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) RabGAP-TBC PF00566.18 CDJ51756.1 - 0.2 11.3 30.9 0.25 10.9 0.0 5.6 6 0 0 6 6 6 0 Rab-GTPase-TBC domain V_ATPase_I PF01496.19 CDJ51756.1 - 0.5 8.2 14.8 0.26 9.2 5.2 3.0 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family MecA PF05389.12 CDJ51756.1 - 4.3 6.9 7.3 3 7.4 1.3 3.1 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) Mit_KHE1 PF10173.9 CDJ51757.1 - 1.6 8.8 7.5 1.8 8.6 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related LCIB_C_CA PF18599.1 CDJ51757.1 - 2.1 7.6 10.8 2.3 7.4 10.8 1.0 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF4366 PF14283.6 CDJ51757.1 - 3.4 7.7 9.8 4.5 7.3 9.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Folliculin PF11704.8 CDJ51757.1 - 4.3 7.2 10.2 4.3 7.2 10.2 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport SAE2 PF08573.10 CDJ51757.1 - 4.9 8.3 15.1 5.9 8.1 15.1 1.1 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus SLC12 PF03522.15 CDJ51759.1 - 3.3 6.6 48.0 4.2 6.3 48.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 CDJ51759.1 - 7.3 4.8 43.1 8.1 4.6 43.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CCSAP PF15748.5 CDJ51759.1 - 8.1 6.5 57.9 9.9 6.3 57.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDK2AP PF09806.9 CDJ51760.1 - 0.012 15.7 3.1 0.015 15.4 3.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Secretin_N_2 PF07655.13 CDJ51760.1 - 0.017 15.7 7.4 0.017 15.7 7.4 1.6 2 0 0 2 2 2 0 Secretin N-terminal domain Herpes_pp85 PF04637.12 CDJ51760.1 - 0.025 13.0 4.2 0.028 12.9 4.2 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3446 PF11928.8 CDJ51760.1 - 0.032 14.5 13.2 0.053 13.8 13.2 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain AF-4 PF05110.13 CDJ51760.1 - 0.12 10.5 16.0 0.15 10.1 16.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Lin-8 PF03353.15 CDJ51760.1 - 0.24 10.9 4.3 0.33 10.5 4.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDP_N PF12278.8 CDJ51760.1 - 0.6 10.3 7.1 1.1 9.4 7.1 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal Corona_nucleoca PF00937.18 CDJ51760.1 - 0.64 9.0 7.7 0.74 8.8 7.7 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4667 PF15700.5 CDJ51760.1 - 0.71 9.9 14.7 0.86 9.7 14.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4667) RAP1 PF07218.11 CDJ51760.1 - 3.3 5.9 6.9 3.5 5.8 6.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YbfN PF13982.6 CDJ51760.1 - 6.3 7.1 9.0 1.3 9.3 5.0 2.0 2 1 0 2 2 2 0 YbfN-like lipoprotein TGT PF01702.18 CDJ51761.1 - 1.3e-92 310.6 12.8 4.1e-74 249.8 0.6 3.9 2 1 2 4 4 4 3 Queuine tRNA-ribosyltransferase SOG2 PF10428.9 CDJ51761.1 - 5 6.2 58.9 2.9 7.0 9.8 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein KH_8 PF17903.1 CDJ51762.1 - 8e-31 106.0 0.1 1.2e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain SUIM_assoc PF16619.5 CDJ51762.1 - 0.4 10.8 8.0 0.89 9.7 8.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 CDJ51762.1 - 0.4 11.0 4.5 0.31 11.4 1.1 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like NST1 PF13945.6 CDJ51762.1 - 1.8 8.6 10.5 2.1 8.4 4.4 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator Ribosomal_60s PF00428.19 CDJ51763.1 - 3 8.5 8.2 5 7.8 8.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein CAC1F_C PF16885.5 CDJ51763.1 - 3.7 7.1 22.0 4.9 6.7 22.0 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term DUF572 PF04502.13 CDJ51763.1 - 5.2 6.6 26.1 6.5 6.3 26.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pkinase PF00069.25 CDJ51766.1 - 3.2e-06 26.7 0.0 3.2e-06 26.7 0.0 2.7 3 1 1 4 4 4 1 Protein kinase domain PilP PF04351.13 CDJ51767.1 - 4.1 7.3 18.1 1.7 8.6 0.9 2.6 2 0 0 2 2 2 0 Pilus assembly protein, PilP Cwf_Cwc_15 PF04889.12 CDJ51767.1 - 5.8 6.6 48.5 1.2 8.8 0.3 4.0 2 1 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF2339 PF10101.9 CDJ51767.1 - 6.6 5.2 38.5 0.7 8.4 0.9 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) CBP_BcsG PF11658.8 CDJ51769.1 - 6.7e-05 21.5 1.9 9.8e-05 20.9 1.9 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG DUF4010 PF13194.6 CDJ51769.1 - 0.00012 21.9 5.7 0.00076 19.2 4.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4010) YfhO PF09586.10 CDJ51769.1 - 0.00016 20.1 3.8 0.00016 20.1 3.8 1.6 2 0 0 2 2 2 1 Bacterial membrane protein YfhO Pex24p PF06398.11 CDJ51769.1 - 0.00019 20.6 1.0 0.00026 20.1 1.0 1.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin SID-1_RNA_chan PF13965.6 CDJ51769.1 - 0.00023 19.7 0.2 0.00027 19.5 0.2 1.3 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 CD20 PF04103.15 CDJ51769.1 - 0.0016 18.6 5.6 0.0016 18.6 5.6 2.3 1 1 1 2 2 1 1 CD20-like family Protocadherin PF08374.11 CDJ51769.1 - 0.003 17.6 1.3 0.0071 16.4 1.3 1.6 1 0 0 1 1 1 1 Protocadherin Shisa PF13908.6 CDJ51769.1 - 0.0038 17.5 1.4 0.0038 17.5 1.4 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Phage_holin_3_6 PF07332.11 CDJ51769.1 - 0.0047 17.0 11.3 0.009 16.0 11.3 1.4 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF898 PF05987.13 CDJ51769.1 - 0.0099 15.0 1.1 0.034 13.2 0.6 1.8 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF898) Wzy_C PF04932.15 CDJ51769.1 - 0.011 15.4 0.4 0.019 14.6 0.5 1.5 1 1 0 1 1 1 0 O-Antigen ligase CitMHS PF03600.16 CDJ51769.1 - 0.013 14.7 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Citrate transporter CLN3 PF02487.17 CDJ51769.1 - 0.014 14.5 11.9 0.016 14.3 5.0 2.0 1 1 1 2 2 2 0 CLN3 protein SARAF PF06682.12 CDJ51769.1 - 0.018 14.7 5.8 0.018 14.7 5.8 2.1 1 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis O-antigen_lig PF13425.6 CDJ51769.1 - 0.022 13.5 1.5 0.027 13.3 1.0 1.3 1 1 0 1 1 1 0 O-antigen ligase like membrane protein CCDC53 PF10152.9 CDJ51769.1 - 0.031 14.7 6.0 0.031 14.7 6.0 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CSG2 PF16965.5 CDJ51769.1 - 0.037 13.0 2.0 0.046 12.7 2.0 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator Folate_carrier PF01770.18 CDJ51769.1 - 0.052 12.3 4.1 0.069 11.9 4.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier FA_desaturase PF00487.24 CDJ51769.1 - 0.054 13.3 3.1 0.077 12.8 2.8 1.4 1 1 0 1 1 1 0 Fatty acid desaturase DUF3810 PF12725.7 CDJ51769.1 - 0.061 12.7 1.2 0.089 12.1 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) OAD_gamma PF04277.13 CDJ51769.1 - 0.1 13.2 0.6 0.1 13.2 0.6 3.0 1 1 1 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Herpes_LMP1 PF05297.11 CDJ51769.1 - 0.11 11.6 5.8 0.15 11.2 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) FHIPEP PF00771.20 CDJ51769.1 - 0.12 10.8 8.6 0.066 11.7 6.3 1.5 1 1 1 2 2 2 0 FHIPEP family Neur_chan_memb PF02932.16 CDJ51769.1 - 0.15 12.1 11.5 0.24 11.4 11.3 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_gE PF02480.16 CDJ51769.1 - 0.23 10.2 0.0 0.23 10.2 0.0 2.0 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E FA_hydroxylase PF04116.13 CDJ51769.1 - 0.28 11.5 1.8 0.4 11.0 1.3 1.5 1 1 0 1 1 1 0 Fatty acid hydroxylase superfamily V_ATPase_I PF01496.19 CDJ51769.1 - 0.31 8.9 21.0 0.0054 14.7 11.8 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF3328 PF11807.8 CDJ51769.1 - 0.81 9.4 10.9 0.94 9.2 8.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) ETRAMP PF09716.10 CDJ51769.1 - 1.9 8.6 7.7 57 3.9 7.7 2.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) OATP PF03137.20 CDJ51769.1 - 1.9 6.7 6.4 0.99 7.6 4.4 1.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S49_N PF08496.10 CDJ51769.1 - 5.1 7.1 16.3 9.7 6.2 15.4 2.1 1 1 0 1 1 1 0 Peptidase family S49 N-terminal G0-G1_switch_2 PF15103.6 CDJ51769.1 - 6.3 7.3 12.2 0.044 14.2 2.6 2.1 2 1 0 2 2 1 0 G0/G1 switch protein 2 DUF1980 PF09323.10 CDJ51769.1 - 7.6 6.4 12.7 0.86 9.5 7.6 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4446 PF14584.6 CDJ51769.1 - 8.5 6.4 14.8 0.034 14.1 3.8 2.2 1 1 1 2 2 1 0 Protein of unknown function (DUF4446) Connexin PF00029.19 CDJ51769.1 - 8.6 6.0 18.6 0.096 12.4 10.1 2.0 1 1 2 3 3 3 0 Connexin PRP38 PF03371.15 CDJ51770.1 - 1.2e-42 145.8 0.1 2.1e-42 144.9 0.1 1.4 1 0 0 1 1 1 1 PRP38 family SART-1 PF03343.13 CDJ51770.1 - 0.006 15.2 0.1 0.006 15.2 0.1 5.2 2 1 2 4 4 4 1 SART-1 family DUF3349 PF11829.8 CDJ51770.1 - 0.16 12.7 4.5 0.32 11.8 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) SR-25 PF10500.9 CDJ51771.1 - 0.00019 21.1 5.6 0.00019 21.1 5.6 10.9 5 2 1 8 8 8 4 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ51771.1 - 0.00044 19.9 14.0 0.00044 19.9 14.0 9.8 4 2 3 8 8 8 1 Spt20 family SseC PF04888.12 CDJ51771.1 - 0.0026 17.4 14.2 0.0026 17.4 14.2 8.1 8 0 0 8 8 8 2 Secretion system effector C (SseC) like family Comm PF15957.5 CDJ51771.1 - 0.046 14.1 0.3 0.046 14.1 0.3 5.3 6 1 0 6 6 6 0 Commissureless Rxt3 PF08642.10 CDJ51771.1 - 0.11 13.2 0.2 0.11 13.2 0.2 8.1 5 5 1 7 7 7 0 Histone deacetylation protein Rxt3 WD40 PF00400.32 CDJ51773.1 - 3.6e-30 103.6 0.0 4.9e-07 30.4 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ51773.1 - 1.3e-11 44.6 0.0 0.0031 17.8 0.0 5.6 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ51773.1 - 3.7e-07 29.2 1.4 0.001 17.8 0.1 3.0 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CDJ51773.1 - 4.7e-06 25.8 1.2 0.024 13.6 0.0 4.3 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CDJ51773.1 - 0.0069 15.7 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain RHH_1 PF01402.21 CDJ51773.1 - 0.11 12.5 0.6 0.93 9.5 0.2 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Roughex PF06020.11 CDJ51774.1 - 0.043 12.9 0.2 0.043 12.9 0.2 2.8 2 1 0 2 2 2 0 Drosophila roughex protein PAT1 PF09770.9 CDJ51774.1 - 0.72 8.1 22.5 1.1 7.5 22.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FHIPEP PF00771.20 CDJ51774.1 - 0.92 7.9 9.8 0.63 8.4 2.4 2.1 1 1 1 2 2 2 0 FHIPEP family DUF4570 PF15134.6 CDJ51774.1 - 1.3 9.1 18.5 0.28 11.2 5.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Pex26 PF07163.12 CDJ51774.1 - 1.4 8.2 26.2 0.038 13.3 8.1 2.5 1 1 1 2 2 2 0 Pex26 protein Chorein_N PF12624.7 CDJ51774.1 - 2 8.6 9.6 6.3 7.0 2.6 2.4 2 0 0 2 2 2 0 N-terminal region of Chorein or VPS13 OmpH PF03938.14 CDJ51774.1 - 2.2 8.6 27.6 1.4 9.2 5.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) eIF_4EBP PF05456.11 CDJ51774.1 - 2.8 7.9 6.3 32 4.5 2.6 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) RRS1 PF04939.12 CDJ51775.1 - 3.2e-20 72.6 10.0 3e-18 66.2 6.8 2.8 1 1 1 2 2 2 2 Ribosome biogenesis regulatory protein (RRS1) UTRA PF07702.13 CDJ51775.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 UTRA domain HEAT PF02985.22 CDJ51776.1 - 0.00015 21.7 9.5 0.13 12.5 0.9 5.1 5 0 0 5 5 5 2 HEAT repeat TFIIA PF03153.13 CDJ51776.1 - 0.0027 17.8 19.9 0.0027 17.8 19.9 4.9 3 1 1 4 4 4 2 Transcription factor IIA, alpha/beta subunit DUF2339 PF10101.9 CDJ51777.1 - 0.0061 15.2 0.1 0.0072 15.0 0.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Spt20 PF12090.8 CDJ51778.1 - 0.027 14.1 0.2 0.037 13.6 0.2 1.2 1 0 0 1 1 1 0 Spt20 family Pro_isomerase PF00160.21 CDJ51780.1 - 1.7e-15 57.6 0.0 2.3e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 CDJ51781.1 - 9.7e-18 64.9 0.0 1.1e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPPK_C PF12555.8 CDJ51781.1 - 0.099 12.7 1.9 0.15 12.1 0.8 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Ribosomal_L23 PF00276.20 CDJ51782.1 - 5.2e-14 52.4 1.3 5.2e-14 52.4 1.3 2.2 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CDJ51782.1 - 0.00083 19.5 14.8 0.00083 19.5 14.8 2.9 3 1 0 3 3 3 1 Ribosomal protein L23, N-terminal domain TusA PF01206.17 CDJ51782.1 - 0.029 14.2 0.1 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 Sulfurtransferase TusA NPR3 PF03666.13 CDJ51782.1 - 0.047 12.5 0.6 0.062 12.1 0.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIA PF03153.13 CDJ51782.1 - 0.064 13.2 7.6 0.083 12.9 7.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HNOBA PF07701.14 CDJ51782.1 - 0.091 12.2 0.2 0.22 11.0 0.1 1.5 1 1 0 1 1 1 0 Heme NO binding associated Ribosomal_60s PF00428.19 CDJ51782.1 - 3.6 8.2 15.2 4.7 7.9 2.5 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Syntaxin-6_N PF09177.11 CDJ51783.1 - 7.8e-10 39.2 9.2 4.5e-09 36.7 1.0 2.5 2 1 0 2 2 2 2 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 CDJ51783.1 - 0.00041 20.0 10.5 0.00051 19.7 10.5 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Nup88 PF10168.9 CDJ51783.1 - 0.0066 14.3 11.4 0.0083 14.0 11.4 1.0 1 0 0 1 1 1 1 Nuclear pore component BLOC1_2 PF10046.9 CDJ51783.1 - 0.0081 16.4 6.7 0.29 11.5 0.2 2.3 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 CDJ51783.1 - 0.016 14.1 13.2 0.021 13.7 13.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 CDJ51783.1 - 0.017 14.2 4.6 0.022 13.9 4.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cbl_N PF02262.16 CDJ51783.1 - 0.058 13.4 0.3 0.099 12.6 0.3 1.4 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 WbqC PF08889.11 CDJ51783.1 - 0.083 12.8 1.0 0.73 9.7 0.5 2.1 1 1 1 2 2 2 0 WbqC-like protein family PspB PF06667.12 CDJ51783.1 - 0.21 11.6 9.3 2 8.5 2.6 3.0 2 1 1 3 3 3 0 Phage shock protein B HemX PF04375.14 CDJ51783.1 - 1.4 8.2 26.6 0.024 13.9 9.0 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase KxDL PF10241.9 CDJ51783.1 - 1.4 9.3 12.3 0.52 10.6 4.5 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein FUN14 PF04930.15 CDJ51783.1 - 2.1 8.8 3.4 3.8 8.0 3.3 1.5 1 1 0 1 1 1 0 FUN14 family DUF948 PF06103.11 CDJ51783.1 - 4 7.8 9.2 5.1 7.4 0.8 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.19 CDJ51784.1 - 0.19 9.6 10.9 0.28 9.1 10.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ketoacyl-synt PF00109.26 CDJ51785.1 - 3.7e-66 223.3 0.0 7.3e-66 222.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CDJ51785.1 - 1.2e-31 109.2 0.1 2.3e-31 108.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 CDJ51785.1 - 1.2e-27 96.8 0.0 6.2e-27 94.4 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 CDJ51785.1 - 2.9e-10 40.4 1.0 6.5e-10 39.2 1.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ligase_CoA PF00549.19 CDJ51788.1 - 5.3e-20 71.8 0.1 9.3e-20 71.0 0.1 1.4 1 1 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 CDJ51788.1 - 2.3e-08 34.6 1.9 3.1e-08 34.2 0.2 2.1 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 CDJ51788.1 - 2.6e-06 27.3 0.2 2.3e-05 24.2 0.2 2.2 1 1 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CDJ51788.1 - 0.053 14.0 1.0 0.34 11.4 0.1 2.5 3 0 0 3 3 3 0 CoA binding domain DUF913 PF06025.12 CDJ51789.1 - 1.1e-05 24.6 6.7 0.0044 16.0 0.9 2.2 2 0 0 2 2 2 2 Domain of Unknown Function (DUF913) DUF383 PF04063.14 CDJ51789.1 - 0.00067 19.4 0.0 0.00067 19.4 0.0 3.6 3 2 0 3 3 2 1 Domain of unknown function (DUF383) DUF2828 PF11443.8 CDJ51789.1 - 0.001 17.3 16.5 0.006 14.7 8.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF2828) SUIM_assoc PF16619.5 CDJ51789.1 - 0.0027 17.7 5.0 0.0027 17.7 5.0 6.0 4 1 0 4 4 3 2 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 CDJ51789.1 - 0.052 14.4 68.8 0.24 12.3 6.0 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit CDC26 Presenilin PF01080.17 CDJ51789.1 - 0.086 11.6 24.8 0.33 9.7 14.2 2.2 2 0 0 2 2 2 0 Presenilin Endostatin PF06482.11 CDJ51789.1 - 0.14 11.6 14.1 0.47 9.9 6.4 2.5 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin EPL1 PF10513.9 CDJ51789.1 - 0.16 12.3 26.7 7 7.0 0.1 4.1 4 0 0 4 4 4 0 Enhancer of polycomb-like RPA43_OB PF17875.1 CDJ51789.1 - 0.32 11.6 13.3 2.1 9.0 2.1 4.0 4 0 0 4 4 4 0 RPA43 OB domain in RNA Pol I Porph_ging PF09697.10 CDJ51789.1 - 0.53 10.8 16.9 0.56 10.8 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (Porph_ging) Peptidase_S49_N PF08496.10 CDJ51789.1 - 0.6 10.2 28.3 4.2 7.4 8.4 4.2 4 0 0 4 4 4 0 Peptidase family S49 N-terminal tRNA_synt_1c_R2 PF04557.15 CDJ51789.1 - 0.63 11.0 18.9 24 5.9 6.8 4.3 4 0 0 4 4 4 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 ALMT PF11744.8 CDJ51789.1 - 0.92 8.3 12.0 0.2 10.4 3.7 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter GEN1_C PF18380.1 CDJ51789.1 - 1.2 10.0 11.5 29 5.6 3.3 3.8 4 0 0 4 4 4 0 Holliday junction resolvase Gen1 C-terminal domain O-antigen_lig PF13425.6 CDJ51789.1 - 1.5 7.5 5.4 1.4 7.7 0.6 2.2 2 0 0 2 2 2 0 O-antigen ligase like membrane protein V_ATPase_I PF01496.19 CDJ51789.1 - 1.7 6.5 19.3 0.58 8.0 9.2 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Orf78 PF06024.12 CDJ51789.1 - 2.1 8.7 17.4 13 6.2 4.4 4.1 4 0 0 4 4 4 0 Orf78 (ac78) CobT PF06213.12 CDJ51789.1 - 2.4 7.4 38.0 5.1 6.4 12.5 4.1 4 0 0 4 4 4 0 Cobalamin biosynthesis protein CobT CAF1 PF04857.20 CDJ51789.1 - 2.8 7.0 25.9 17 4.5 18.3 2.4 1 1 1 2 2 2 0 CAF1 family ribonuclease DUF5327 PF17261.2 CDJ51789.1 - 4 8.3 43.2 6.4 7.6 1.2 4.3 4 0 0 4 4 4 0 Family of unknown function (DUF5327) DUF1840 PF08895.11 CDJ51789.1 - 6.6 7.1 27.2 18 5.7 0.8 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1840) AIF_C PF14721.6 CDJ51789.1 - 8 6.8 20.8 5.7 7.3 4.3 4.1 4 0 0 4 4 4 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Erv26 PF04148.13 CDJ51789.1 - 8.5 6.1 5.5 6.4 6.5 0.2 2.8 3 0 0 3 3 3 0 Transmembrane adaptor Erv26 Serinc PF03348.15 CDJ51789.1 - 9.2 5.1 15.8 0.18 10.7 4.8 2.3 2 1 0 2 2 2 0 Serine incorporator (Serinc) Peptidase_C14 PF00656.22 CDJ51790.1 - 1e-08 35.5 0.0 1e-08 35.5 0.0 2.6 2 1 0 2 2 2 1 Caspase domain Ribosomal_60s PF00428.19 CDJ51790.1 - 5.3e-05 23.7 7.5 0.0024 18.4 0.4 2.5 2 0 0 2 2 2 2 60s Acidic ribosomal protein DUF4148 PF13663.6 CDJ51790.1 - 0.027 14.7 10.9 1.6 8.9 0.3 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DDE_Tnp_4 PF13359.6 CDJ51790.1 - 0.88 9.2 4.0 2.7 7.6 0.6 2.5 2 0 0 2 2 2 0 DDE superfamily endonuclease DUF5529 PF17669.1 CDJ51790.1 - 3.9 7.5 8.9 0.39 10.7 0.7 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5529) TAT_signal PF10518.9 CDJ51790.1 - 4.4 7.3 35.7 3.3 7.7 16.7 2.5 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence BCS1_N PF08740.11 CDJ51791.1 - 4.3e-10 39.9 1.3 1.1e-09 38.6 1.3 1.6 1 1 0 1 1 1 1 BCS1 N terminal DUF2722 PF10846.8 CDJ51791.1 - 1.5e-06 27.5 2.3 1.6e-06 27.4 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ51791.1 - 0.0098 15.9 13.2 0.012 15.6 13.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ51791.1 - 0.016 15.8 9.4 0.021 15.5 9.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MG3 PF17791.1 CDJ51791.1 - 0.032 14.5 0.2 0.052 13.8 0.2 1.3 1 0 0 1 1 1 0 Macroglobulin domain MG3 DUF5349 PF17298.2 CDJ51791.1 - 0.055 13.2 7.5 0.077 12.7 7.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Rxt3 PF08642.10 CDJ51791.1 - 0.11 13.3 0.0 0.14 12.9 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF1538 PF07556.11 CDJ51791.1 - 0.12 11.6 2.1 1.3 8.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) Suf PF05843.14 CDJ51791.1 - 0.13 12.2 7.1 0.17 11.8 7.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med3 PF11593.8 CDJ51791.1 - 0.22 10.7 10.9 0.3 10.2 10.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Activator_LAG-3 PF11498.8 CDJ51791.1 - 0.3 10.0 20.5 0.46 9.4 20.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Roughex PF06020.11 CDJ51791.1 - 0.45 9.6 8.9 0.16 11.0 6.6 1.4 2 0 0 2 2 2 0 Drosophila roughex protein Spt20 PF12090.8 CDJ51791.1 - 0.95 9.0 25.6 1.5 8.4 25.6 1.2 1 0 0 1 1 1 0 Spt20 family PRIMA1 PF16101.5 CDJ51791.1 - 1.4 9.0 8.7 3 7.9 8.7 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 UPF0560 PF10577.9 CDJ51791.1 - 2.6 6.5 8.5 4.1 5.8 8.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Neur_chan_memb PF02932.16 CDJ51791.1 - 3.6 7.6 12.7 5.3 7.0 0.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RAB3GAP2_N PF14655.6 CDJ51791.1 - 8.5 5.5 7.7 11 5.1 7.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pribosyltran_N PF13793.6 CDJ51792.1 - 4.1e-48 162.1 0.1 2.5e-47 159.6 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CDJ51792.1 - 4.2e-34 118.2 1.2 7.5e-34 117.4 1.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CDJ51792.1 - 2.5e-13 49.9 0.2 5.3e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CDJ51792.1 - 0.0018 17.7 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase LEP503 PF15221.6 CDJ51792.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 ANAPC4_WD40 PF12894.7 CDJ51794.1 - 5.7e-12 45.8 0.9 0.0098 16.2 0.0 4.8 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain RskA PF10099.9 CDJ51794.1 - 3.3e-05 24.3 1.0 3.3e-05 24.3 1.0 22.8 7 6 7 17 17 17 4 Anti-sigma-K factor rskA SPX PF03105.19 CDJ51794.1 - 0.0011 19.0 9.6 0.0011 19.0 9.6 10.8 5 4 0 5 5 5 1 SPX domain WD40 PF00400.32 CDJ51794.1 - 0.45 11.5 11.9 18 6.4 0.6 5.5 5 0 0 5 5 5 0 WD domain, G-beta repeat LcrG PF07216.12 CDJ51795.1 - 0.014 15.3 1.3 0.019 14.9 1.3 1.3 1 0 0 1 1 1 0 LcrG protein DUF1840 PF08895.11 CDJ51795.1 - 0.038 14.3 1.4 0.041 14.2 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF853 PF05872.12 CDJ51795.1 - 0.067 11.8 1.6 0.072 11.7 1.6 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) STAG PF08514.11 CDJ51795.1 - 0.12 12.4 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 STAG domain Coprogen_oxidas PF01218.18 CDJ51796.1 - 4.1e-33 114.4 1.7 4.1e-33 114.4 1.7 2.1 1 1 0 2 2 1 1 Coproporphyrinogen III oxidase Presenilin PF01080.17 CDJ51796.1 - 0.02 13.7 30.7 0.026 13.3 30.7 1.1 1 0 0 1 1 1 0 Presenilin Mpp10 PF04006.12 CDJ51796.1 - 0.042 12.3 38.6 0.052 12.0 38.6 1.0 1 0 0 1 1 1 0 Mpp10 protein SRP-alpha_N PF04086.13 CDJ51796.1 - 0.72 9.7 29.5 1 9.2 29.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GAGA_bind PF06217.12 CDJ51796.1 - 1.2 9.3 24.0 1.7 8.9 24.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2151 PF10221.9 CDJ51796.1 - 1.4 7.4 16.3 1.8 7.0 16.3 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator Zip PF02535.22 CDJ51796.1 - 1.8 7.7 16.4 2.6 7.2 16.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ECM1 PF05782.11 CDJ51796.1 - 2 7.2 22.5 2.6 6.9 22.5 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Raftlin PF15250.6 CDJ51796.1 - 2.1 7.0 24.4 2.7 6.7 24.4 1.1 1 0 0 1 1 1 0 Raftlin Neur_chan_memb PF02932.16 CDJ51796.1 - 2.9 7.9 23.9 4.4 7.3 23.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Smg8_Smg9 PF10220.9 CDJ51796.1 - 5.8 5.1 26.3 7 4.8 26.3 1.0 1 0 0 1 1 1 0 Smg8_Smg9 FAM60A PF15396.6 CDJ51796.1 - 7.1 6.6 26.2 12 5.8 26.2 1.4 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 CDJ51796.1 - 8.1 5.3 33.6 11 4.8 33.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Exonuc_VII_L PF02601.15 CDJ51796.1 - 9 5.8 25.2 11 5.4 25.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4342 PF14242.6 CDJ51797.1 - 0.0035 17.3 0.0 0.0035 17.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4342) DUF677 PF05055.12 CDJ51797.1 - 0.083 11.8 1.9 0.14 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF677) DUF4813 PF16072.5 CDJ51797.1 - 2.8 7.5 36.1 1.4 8.5 19.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) DUF572 PF04502.13 CDJ51797.1 - 4.1 6.9 21.7 5.1 6.6 21.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) LMBR1 PF04791.16 CDJ51797.1 - 8.7 5.1 10.6 10 4.9 10.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pex14_N PF04695.13 CDJ51797.1 - 9.3 6.9 48.7 11 6.6 26.3 2.3 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.9 CDJ51798.1 - 3e-05 23.7 6.7 3e-05 23.7 6.7 6.6 5 1 2 7 7 7 3 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ51798.1 - 0.0091 16.3 1.4 0.0091 16.3 1.4 5.0 2 2 1 3 3 3 1 Anti-sigma-K factor rskA PAT1 PF09770.9 CDJ51799.1 - 0.014 13.7 21.7 0.014 13.7 21.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EOS1 PF12326.8 CDJ51799.1 - 0.015 15.3 0.4 0.015 15.3 0.4 1.2 1 0 0 1 1 1 0 N-glycosylation protein Neur_chan_memb PF02932.16 CDJ51799.1 - 0.029 14.4 5.8 0.03 14.4 5.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 CDJ51799.1 - 0.077 11.4 0.4 0.068 11.6 0.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 CDJ51799.1 - 0.84 8.3 19.8 1.1 8.0 19.8 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 CDJ51799.1 - 1.5 9.0 13.6 2 8.5 13.6 1.2 1 0 0 1 1 1 0 DDHD domain PX PF00787.24 CDJ51800.1 - 8.1e-18 64.5 0.1 8.1e-18 64.5 0.1 3.8 4 1 1 5 5 5 1 PX domain WD40 PF00400.32 CDJ51800.1 - 0.00053 20.7 0.2 0.13 13.2 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat Pex14_N PF04695.13 CDJ51800.1 - 0.0048 17.6 3.7 0.0048 17.6 3.7 7.7 4 2 2 6 6 6 2 Peroxisomal membrane anchor protein (Pex14p) conserved region CDK2AP PF09806.9 CDJ51800.1 - 0.014 15.5 10.2 0.014 15.5 10.2 7.0 4 2 2 6 6 6 0 Cyclin-dependent kinase 2-associated protein DUF5058 PF16481.5 CDJ51801.1 - 0.031 14.0 0.6 0.045 13.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) PIG-S PF10510.9 CDJ51801.1 - 1.3 7.8 35.3 1.9 7.2 35.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF3295 PF11702.8 CDJ51801.1 - 1.9 7.7 49.3 3 7.1 49.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Virul_fac_BrkB PF03631.15 CDJ51801.1 - 4.9 6.7 4.4 3.8 7.0 3.3 1.4 1 1 0 1 1 1 0 Virulence factor BrkB SPX PF03105.19 CDJ51801.1 - 6.4 6.6 34.0 9.9 6.0 34.0 1.3 1 0 0 1 1 1 0 SPX domain DUF4131 PF13567.6 CDJ51802.1 - 1.1 8.8 6.4 2.7 7.6 1.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF2076 PF09849.9 CDJ51803.1 - 0.0073 16.4 37.2 0.0073 16.4 37.2 3.4 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) CAF1 PF04857.20 CDJ51803.1 - 0.086 12.0 19.9 0.021 14.0 9.6 2.4 2 0 0 2 2 2 0 CAF1 family ribonuclease VIR_N PF15912.5 CDJ51803.1 - 0.091 12.4 18.4 0.052 13.1 10.5 2.3 2 0 0 2 2 2 0 Virilizer, N-terminal V_ATPase_I PF01496.19 CDJ51803.1 - 0.091 10.7 38.8 0.031 12.2 25.7 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Velvet PF11754.8 CDJ51803.1 - 0.47 10.4 42.3 2.2 8.1 8.2 2.5 2 0 0 2 2 2 0 Velvet factor Endostatin PF06482.11 CDJ51803.1 - 2.2 7.7 41.1 2.1 7.7 27.0 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin FAM76 PF16046.5 CDJ51803.1 - 5.4 6.3 42.2 0.29 10.4 30.2 2.9 3 0 0 3 3 3 0 FAM76 protein Zip PF02535.22 CDJ51803.1 - 5.5 6.1 21.9 1.1 8.4 16.9 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter CobN-Mg_chel PF02514.16 CDJ51804.1 - 0.039 11.7 10.7 0.005 14.7 5.9 1.7 2 0 0 2 2 2 0 CobN/Magnesium Chelatase SLC12 PF03522.15 CDJ51804.1 - 1 8.3 14.2 0.35 9.8 8.6 2.3 2 0 0 2 2 2 0 Solute carrier family 12 Presenilin PF01080.17 CDJ51804.1 - 1.1 8.0 17.4 0.68 8.6 9.8 2.7 3 0 0 3 3 3 0 Presenilin GREB1 PF15782.5 CDJ51804.1 - 4.7 4.2 16.7 8.5 3.3 16.7 1.4 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer V_ATPase_I PF01496.19 CDJ51804.1 - 7.8 4.3 14.2 6.4 4.6 9.0 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 CDJ51804.1 - 7.8 5.4 11.0 1.6 7.7 4.8 2.3 2 0 0 2 2 2 0 CLN3 protein Lin-8 PF03353.15 CDJ51804.1 - 9.3 5.7 23.7 1.6 8.3 12.3 3.0 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist DFRP_C PF16543.5 CDJ51805.1 - 1 9.9 5.7 2.4 8.7 4.5 2.3 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 DUF1772 PF08592.11 CDJ51805.1 - 2.4 8.4 10.6 17 5.7 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) zf-C4H2 PF10146.9 CDJ51805.1 - 2.6 8.3 0.0 2.6 8.3 0.0 9.0 1 1 1 2 2 2 0 Zinc finger-containing protein SUIM_assoc PF16619.5 CDJ51806.1 - 1 9.5 4.5 5.6 7.1 0.1 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 CDJ51807.1 - 4e-07 30.6 11.9 0.075 13.9 0.1 5.9 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ51807.1 - 0.029 14.6 0.1 91 3.5 0.0 4.7 5 1 1 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain MPS2 PF17060.5 CDJ51807.1 - 0.13 11.5 4.6 0.23 10.7 4.6 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 Rhomboid PF01694.22 CDJ51808.1 - 4.1e-05 23.6 2.0 7.6e-05 22.7 2.0 1.5 1 1 0 1 1 1 1 Rhomboid family RRN3 PF05327.11 CDJ51809.1 - 0.38 9.2 5.1 0.5 8.8 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.14 CDJ51809.1 - 7.3 6.3 9.1 12 5.6 9.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein eIF-3_zeta PF05091.12 CDJ51810.1 - 0.0085 15.1 20.2 0.11 11.5 13.1 2.1 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PepSY_TM PF03929.16 CDJ51810.1 - 0.018 14.7 12.1 0.034 13.8 0.7 2.5 2 0 0 2 2 2 0 PepSY-associated TM region RskA PF10099.9 CDJ51810.1 - 0.019 15.3 35.0 1.8e+04 -6.6 35.0 3.6 1 1 0 1 1 0 0 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ51810.1 - 0.034 13.1 46.2 0.44 9.4 9.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spore_coat_CotO PF14153.6 CDJ51810.1 - 0.043 13.7 24.0 0.54 10.2 2.5 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Connexin PF00029.19 CDJ51810.1 - 0.093 12.5 10.4 0.28 10.9 5.0 2.4 2 0 0 2 2 2 0 Connexin Pinin_SDK_memA PF04696.13 CDJ51810.1 - 0.098 12.7 34.1 0.12 12.4 15.9 2.4 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region SpoIIP PF07454.11 CDJ51810.1 - 0.12 11.8 19.6 0.32 10.4 11.9 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Med15 PF09606.10 CDJ51810.1 - 0.12 11.0 43.8 0.38 9.4 28.3 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal HNOBA PF07701.14 CDJ51810.1 - 0.21 11.0 11.3 0.32 10.4 4.0 2.4 2 0 0 2 2 2 0 Heme NO binding associated BRF1 PF07741.13 CDJ51810.1 - 0.26 11.7 16.8 1.7 9.0 8.7 2.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain CobT PF06213.12 CDJ51810.1 - 0.58 9.5 30.6 0.27 10.6 16.9 2.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF4770 PF15994.5 CDJ51810.1 - 1.1 9.5 22.5 1.6 8.9 12.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Asp-B-Hydro_N PF05279.11 CDJ51810.1 - 1.7 8.7 13.3 2.8 7.9 4.1 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Pet20 PF08692.10 CDJ51810.1 - 1.9 9.2 8.3 1.2 9.8 1.8 2.5 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Peptidase_S49_N PF08496.10 CDJ51810.1 - 1.9 8.5 14.8 1.2 9.2 6.5 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3391 PF11871.8 CDJ51810.1 - 2.1 8.9 26.7 7.9 7.0 16.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) RED_N PF07808.13 CDJ51810.1 - 2.3 7.8 21.8 2.2 7.8 2.5 2.3 2 0 0 2 2 2 0 RED-like protein N-terminal region RR_TM4-6 PF06459.12 CDJ51810.1 - 2.5 7.9 21.8 6.3 6.5 14.4 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 CDJ51810.1 - 2.9 6.6 16.1 3.1 6.5 10.2 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 HA2 PF04408.23 CDJ51810.1 - 2.9 8.2 11.3 2.6 8.4 4.3 2.6 2 0 0 2 2 2 0 Helicase associated domain (HA2) PA26 PF04636.13 CDJ51810.1 - 3.6 6.4 14.9 3 6.7 5.3 2.3 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) DUF1980 PF09323.10 CDJ51810.1 - 5 7.0 13.5 1.4 8.8 6.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Activator_LAG-3 PF11498.8 CDJ51810.1 - 5.2 5.9 63.3 0.29 10.0 32.9 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 MCU PF04678.13 CDJ51810.1 - 8.7 6.4 11.7 14 5.7 0.5 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF2828 PF11443.8 CDJ51810.1 - 9.5 4.2 19.2 1.4 6.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) B56 PF01603.20 CDJ51811.1 - 3.8e-156 520.2 2.3 3.8e-156 520.2 2.3 1.9 3 0 0 3 3 3 1 Protein phosphatase 2A regulatory B subunit (B56 family) DNA_ligase_aden PF01653.18 CDJ51811.1 - 8.2e-40 136.8 2.3 1.6e-12 47.2 0.0 6.7 6 1 0 6 6 6 5 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 CDJ51811.1 - 6.2e-22 77.3 0.0 1.2e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain DUF4834 PF16118.5 CDJ51811.1 - 0.18 12.8 0.0 0.18 12.8 0.0 6.7 7 1 0 7 7 7 0 Domain of unknown function (DUF4834) Oxysterol_BP PF01237.18 CDJ51813.1 - 1.5e-06 27.4 0.3 8.4e-06 24.9 0.0 2.4 3 0 0 3 3 3 1 Oxysterol-binding protein Kinesin PF00225.23 CDJ51814.1 - 1.7e-17 63.4 0.0 1.7e-17 63.4 0.0 4.8 3 1 0 4 4 4 2 Kinesin motor domain SUIM_assoc PF16619.5 CDJ51814.1 - 0.0059 16.7 2.9 0.0059 16.7 2.9 8.3 2 2 3 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 PK PF00224.21 CDJ51816.1 - 8e-35 120.3 0.3 7.8e-25 87.5 2.8 4.2 3 1 1 4 4 4 4 Pyruvate kinase, barrel domain PK_C PF02887.16 CDJ51816.1 - 1.2e-12 48.1 0.0 1.1e-11 45.0 0.0 2.6 1 1 0 1 1 1 1 Pyruvate kinase, alpha/beta domain DDHD PF02862.17 CDJ51816.1 - 0.2 11.8 22.3 7.1 6.7 0.1 3.5 3 0 0 3 3 3 0 DDHD domain CNDH2_C PF16858.5 CDJ51816.1 - 0.67 9.8 24.3 4 7.2 0.7 3.2 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Caldesmon PF02029.15 CDJ51816.1 - 0.79 8.4 28.8 0.65 8.7 0.7 3.1 3 0 0 3 3 3 0 Caldesmon PNISR PF15996.5 CDJ51816.1 - 1 9.6 36.3 0.57 10.4 0.9 3.5 3 0 0 3 3 3 0 Arginine/serine-rich protein PNISR DUF2052 PF09747.9 CDJ51816.1 - 2.1 8.4 40.3 0.39 10.8 4.8 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Neur_chan_memb PF02932.16 CDJ51816.1 - 3.9 7.5 24.1 17 5.4 0.4 3.4 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ51816.1 - 4.3 6.0 36.5 2.4 6.8 0.4 3.1 3 0 0 3 3 3 0 Presenilin FAM60A PF15396.6 CDJ51816.1 - 4.8 7.1 18.5 16 5.5 10.8 3.1 3 0 0 3 3 3 0 Protein Family FAM60A AUX_IAA PF02309.16 CDJ51816.1 - 6.1 6.6 21.0 43 3.9 0.0 3.2 3 0 0 3 3 3 0 AUX/IAA family DHQ_synthase PF01761.20 CDJ51817.1 - 4.6e-56 189.9 12.2 2.4e-36 125.3 0.0 3.7 2 1 1 3 3 3 2 3-dehydroquinate synthase Spt20 PF12090.8 CDJ51817.1 - 0.00091 18.9 14.9 0.00091 18.9 14.9 6.5 5 2 0 5 5 5 1 Spt20 family FAM104 PF15434.6 CDJ51817.1 - 0.041 14.4 0.0 0.041 14.4 0.0 7.3 4 2 1 6 6 6 0 Family 104 PPP4R2 PF09184.11 CDJ51818.1 - 5.9 6.4 20.6 9.7 5.7 0.6 2.5 2 0 0 2 2 2 0 PPP4R2 AMP-binding PF00501.28 CDJ51819.1 - 2 6.9 5.9 2.4 6.7 5.9 1.1 1 0 0 1 1 1 0 AMP-binding enzyme MMU163 PF17119.5 CDJ51819.1 - 6.9 5.7 12.0 8.4 5.5 12.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis VPS13 PF16908.5 CDJ51821.1 - 7e-13 48.9 7.6 7e-13 48.9 7.6 4.7 4 1 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal TAF4 PF05236.14 CDJ51821.1 - 0.00014 21.8 15.8 0.00014 21.8 15.8 11.3 8 2 1 9 9 9 2 Transcription initiation factor TFIID component TAF4 family Herpes_capsid PF06112.11 CDJ51821.1 - 0.0021 18.2 17.9 0.0021 18.2 17.9 11.7 10 1 1 11 11 11 2 Gammaherpesvirus capsid protein ETRAMP PF09716.10 CDJ51821.1 - 1.4 9.0 0.0 1.4 9.0 0.0 5.4 8 1 0 8 8 8 0 Malarial early transcribed membrane protein (ETRAMP) CCDC117 PF15810.5 CDJ51822.1 - 0.71 10.2 0.0 0.71 10.2 0.0 8.3 9 1 0 9 9 9 0 Coiled-coil domain-containing protein 117 SPX PF03105.19 CDJ51822.1 - 1.2 9.0 0.0 1.2 9.0 0.0 7.9 2 2 2 5 5 5 0 SPX domain dCache_2 PF08269.11 CDJ51823.1 - 0.055 12.6 1.2 0.1 11.8 1.2 1.4 1 0 0 1 1 1 0 Cache domain Mac PF12464.8 CDJ51823.1 - 0.11 12.8 2.9 0.12 12.6 1.1 2.1 2 0 0 2 2 2 0 Maltose acetyltransferase GLTSCR1 PF15249.6 CDJ51823.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.4 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein PID PF00640.23 CDJ51823.1 - 0.18 11.8 4.2 0.046 13.7 1.0 1.6 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) FUSC PF04632.12 CDJ51823.1 - 0.22 10.0 13.0 0.007 15.0 6.4 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family SKA1 PF07160.12 CDJ51823.1 - 0.46 10.3 8.8 0.1 12.4 2.1 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF1664 PF07889.12 CDJ51823.1 - 3.5 7.7 10.0 11 6.1 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ly49 PF08391.10 CDJ51823.1 - 5.7 7.3 9.2 1 9.8 0.6 2.3 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region ACP_syn_III PF08545.10 CDJ51824.1 - 0.014 15.3 0.1 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1116 PF06545.11 CDJ51824.1 - 1 8.7 9.5 0.85 9.0 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1116) Glucan_synthase PF02364.15 CDJ51827.1 - 5.1e-135 451.7 2.2 5.8e-114 382.0 4.1 2.5 2 0 0 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CDJ51827.1 - 1.4e-12 48.1 5.4 1.8e-10 41.2 5.4 2.5 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 FKBP_C PF00254.28 CDJ51829.1 - 5.4e-23 81.1 0.0 7.9e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Phage_TAC_11 PF11836.8 CDJ51830.1 - 0.047 13.8 0.2 0.095 12.8 0.2 1.4 1 0 0 1 1 1 0 Phage tail tube protein, GTA-gp10 CAP_C PF08603.11 CDJ51831.1 - 1.4e-51 174.2 1.3 1.5e-51 174.1 1.3 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 CDJ51831.1 - 1.9e-05 24.4 2.7 2.9e-05 23.8 2.7 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C RRM_1 PF00076.22 CDJ51832.1 - 0.004 16.9 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1744 PF08490.12 CDJ51835.1 - 4.4e-08 32.1 0.1 4.4e-08 32.1 0.1 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1744) RskA PF10099.9 CDJ51835.1 - 0.0011 19.2 0.0 0.0011 19.2 0.0 7.9 3 3 2 5 5 5 2 Anti-sigma-K factor rskA PRCC PF10253.9 CDJ51835.1 - 0.003 18.4 19.9 0.003 18.4 19.9 5.7 4 2 0 4 4 4 1 Mitotic checkpoint regulator, MAD2B-interacting Nop53 PF07767.11 CDJ51835.1 - 0.0056 16.1 24.3 0.0056 16.1 24.3 4.1 3 1 0 3 3 3 1 Nop53 (60S ribosomal biogenesis) DUF572 PF04502.13 CDJ51835.1 - 0.02 14.5 58.9 0.55 9.8 20.9 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF572) ASD2 PF08687.11 CDJ51835.1 - 3.5 7.1 57.8 1 8.9 17.3 4.8 4 0 0 4 4 4 0 Apx/Shroom domain ASD2 CCSAP PF15748.5 CDJ51835.1 - 3.7 7.6 93.9 0.022 14.9 32.2 4.5 3 1 0 4 4 4 0 Centriole, cilia and spindle-associated TCP PF03634.13 CDJ51835.1 - 3.8 8.1 79.4 0.087 13.4 30.1 4.6 4 0 0 4 4 4 0 TCP family transcription factor RRM_1 PF00076.22 CDJ51836.1 - 0.00024 20.8 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CDJ51836.1 - 0.12 12.3 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 RL domain Ribosomal_60s PF00428.19 CDJ51836.1 - 0.19 12.3 16.2 0.3 11.7 16.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein UDPGP PF01704.18 CDJ51837.1 - 9.9e-05 21.1 1.2 0.019 13.7 0.1 2.9 3 0 0 3 3 3 2 UTP--glucose-1-phosphate uridylyltransferase Spt20 PF12090.8 CDJ51837.1 - 0.0012 18.5 4.5 0.0012 18.5 4.5 4.5 3 1 1 4 4 4 2 Spt20 family DUF2722 PF10846.8 CDJ51837.1 - 0.0017 17.4 4.1 0.0017 17.4 4.1 4.6 4 1 0 4 4 3 2 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ51837.1 - 0.009 16.1 3.8 0.009 16.1 3.8 6.5 6 2 1 7 7 3 2 Unstructured region C-term to UIM in Ataxin3 Med15 PF09606.10 CDJ51837.1 - 0.014 14.1 47.9 0.11 11.1 2.3 3.3 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal SPX PF03105.19 CDJ51837.1 - 0.38 10.6 36.6 0.45 10.4 1.6 2.7 1 1 1 2 2 2 0 SPX domain AAA_23 PF13476.6 CDJ51837.1 - 0.43 11.0 15.2 0.51 10.8 0.4 3.4 3 0 0 3 3 3 0 AAA domain EIIBC-GUT_N PF03612.14 CDJ51837.1 - 3.2 7.5 16.6 2.4 7.8 0.1 3.9 4 0 0 4 4 4 0 Sorbitol phosphotransferase enzyme II N-terminus RR_TM4-6 PF06459.12 CDJ51837.1 - 3.2 7.5 22.8 0.21 11.4 0.7 3.8 4 0 0 4 4 4 0 Ryanodine Receptor TM 4-6 AF-4 PF05110.13 CDJ51837.1 - 3.3 5.7 64.2 0.015 13.4 4.9 3.4 3 1 0 3 3 3 0 AF-4 proto-oncoprotein RskA PF10099.9 CDJ51837.1 - 4.4 7.6 54.0 6 7.1 0.1 4.7 3 1 0 3 3 2 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ51838.1 - 0.015 14.1 5.1 0.019 13.7 5.1 1.2 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ51838.1 - 0.019 14.6 25.3 0.2 11.2 14.1 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 CDJ51838.1 - 0.032 14.8 8.3 0.032 14.8 8.3 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4663 PF15668.5 CDJ51838.1 - 0.087 11.9 1.4 0.17 10.9 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) SelB-wing_2 PF09106.11 CDJ51838.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF789 PF05623.12 CDJ51838.1 - 1.1 8.9 8.2 1.4 8.6 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF789) FlgH PF02107.16 CDJ51838.1 - 1.3 8.6 13.3 0.2 11.3 3.0 2.3 2 0 0 2 2 2 0 Flagellar L-ring protein AF-4 PF05110.13 CDJ51838.1 - 3.7 5.5 28.6 0.33 9.0 3.8 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein MRI PF15325.6 CDJ51838.1 - 5.5 8.1 10.5 2.2 9.4 0.8 2.7 2 0 0 2 2 2 0 Modulator of retrovirus infection CCDC106 PF15794.5 CDJ51838.1 - 5.6 6.6 16.8 5.2 6.7 3.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 SR-25 PF10500.9 CDJ51839.1 - 5.9 6.4 72.2 0.27 10.8 9.2 4.2 2 1 2 4 4 4 0 Nuclear RNA-splicing-associated protein CAF1 PF04857.20 CDJ51841.1 - 1.1e-19 70.8 0.5 1.3e-13 50.8 0.0 3.3 1 1 1 3 3 2 2 CAF1 family ribonuclease AAA_23 PF13476.6 CDJ51841.1 - 0.0016 19.0 11.2 0.6 10.6 0.1 2.5 2 1 0 2 2 2 2 AAA domain Trypan_PARP PF05887.11 CDJ51841.1 - 0.045 13.7 0.7 0.069 13.1 0.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FliP PF00813.20 CDJ51841.1 - 0.066 13.1 1.9 0.13 12.2 1.9 1.4 1 0 0 1 1 1 0 FliP family SAPS PF04499.15 CDJ51841.1 - 0.37 9.5 11.8 0.63 8.8 11.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SUIM_assoc PF16619.5 CDJ51841.1 - 0.47 10.6 0.0 0.079 13.0 5.7 6.6 3 2 1 4 4 3 0 Unstructured region C-term to UIM in Ataxin3 Lin-8 PF03353.15 CDJ51841.1 - 0.63 9.6 35.4 0.13 11.8 4.6 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist IMUP PF15761.5 CDJ51841.1 - 1.4 9.6 30.7 0.7 10.6 6.8 2.6 2 1 0 2 2 2 0 Immortalisation up-regulated protein DUF2370 PF10176.9 CDJ51841.1 - 1.4 8.5 6.9 3.6 7.2 6.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) SARAF PF06682.12 CDJ51841.1 - 2.3 7.8 38.6 0.058 13.0 14.2 2.3 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis PIP5K PF01504.18 CDJ51841.1 - 2.6 7.2 13.7 25 4.0 13.7 2.3 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase PPP4R2 PF09184.11 CDJ51841.1 - 3 7.4 13.3 4.6 6.8 13.3 1.3 1 0 0 1 1 1 0 PPP4R2 CrgA PF06781.12 CDJ51841.1 - 5.1 7.2 5.3 1.8 8.7 0.1 2.6 2 0 0 2 2 2 0 Cell division protein CrgA Glyco_hydro_106 PF17132.4 CDJ51843.1 - 0.075 11.3 0.0 0.076 11.3 0.0 1.0 1 0 0 1 1 1 0 alpha-L-rhamnosidase CRAL_TRIO PF00650.20 CDJ51844.1 - 1.3e-05 25.0 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Drf_DAD PF06345.11 CDJ51845.1 - 0.16 12.1 0.1 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 DRF Autoregulatory Domain PsbQ PF05757.11 CDJ51846.1 - 0.038 13.7 0.9 0.082 12.6 0.9 1.5 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF1778 PF08681.11 CDJ51846.1 - 0.073 13.0 0.3 0.15 12.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) RskA PF10099.9 CDJ51846.1 - 0.086 13.1 6.2 0.14 12.5 5.6 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Radical_SAM PF04055.21 CDJ51847.1 - 2.5e-10 41.0 0.0 3.6e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 CDJ51847.1 - 5.6e-05 23.3 0.0 8.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3537 PF12056.8 CDJ51847.1 - 0.0093 14.8 0.1 0.012 14.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3537) Pkinase PF00069.25 CDJ51848.1 - 8e-11 41.8 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ51848.1 - 4.1e-10 39.4 0.0 1.1e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ51848.1 - 0.0062 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PUD1_2 PF18457.1 CDJ51849.1 - 0.11 12.5 2.3 0.11 12.4 0.5 1.9 1 1 1 2 2 2 0 Up-Regulated in long-lived daf-2 Tic110 PF16940.5 CDJ51849.1 - 8.3 4.8 12.1 12 4.2 12.1 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter Sporozoite_P67 PF05642.11 CDJ51850.1 - 4.9e-05 21.6 0.0 4.9e-05 21.6 0.0 6.8 3 2 1 4 4 4 1 Sporozoite P67 surface antigen FA_desaturase PF00487.24 CDJ51851.1 - 0.099 12.5 0.0 4.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Fatty acid desaturase DUF3040 PF11239.8 CDJ51851.1 - 0.2 12.0 5.5 1.5 9.1 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF572 PF04502.13 CDJ51851.1 - 0.61 9.6 33.2 0.89 9.1 33.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SARAF PF06682.12 CDJ51851.1 - 2.9 7.5 35.6 10 5.7 34.2 1.9 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SID-1_RNA_chan PF13965.6 CDJ51852.1 - 0.042 12.3 14.6 0.046 12.1 14.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PPP4R2 PF09184.11 CDJ51852.1 - 0.37 10.3 19.7 0.38 10.3 19.7 1.1 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.12 CDJ51852.1 - 0.43 10.3 36.6 0.5 10.2 36.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF726 PF05277.12 CDJ51852.1 - 0.64 8.9 4.5 0.72 8.7 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) SART-1 PF03343.13 CDJ51852.1 - 0.77 8.2 36.6 0.78 8.2 36.6 1.0 1 0 0 1 1 1 0 SART-1 family MgsA_C PF12002.8 CDJ51852.1 - 0.83 9.6 28.5 0.94 9.4 28.5 1.0 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Hamartin PF04388.12 CDJ51852.1 - 1.4 7.5 35.3 1.6 7.3 35.3 1.0 1 0 0 1 1 1 0 Hamartin protein V_ATPase_I PF01496.19 CDJ51852.1 - 2.3 6.0 30.9 2.9 5.7 30.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family VIR_N PF15912.5 CDJ51852.1 - 3.4 7.2 22.5 3.7 7.1 22.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF2828 PF11443.8 CDJ51852.1 - 5.2 5.0 30.2 6.3 4.7 30.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Miga PF10265.9 CDJ51852.1 - 5.9 5.7 23.6 6.9 5.5 23.6 1.1 1 0 0 1 1 1 0 Mitoguardin Peptidase_S64 PF08192.11 CDJ51852.1 - 6.1 5.2 27.0 6.3 5.2 27.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 ADP_ribosyl_GH PF03747.14 CDJ51852.1 - 6.4 6.4 16.5 8.4 6.0 16.5 1.3 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Sec62 PF03839.16 CDJ51852.1 - 8.1 5.9 26.7 9.6 5.7 26.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 HemX PF04375.14 CDJ51852.1 - 9.9 5.3 62.1 11 5.2 62.1 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase MACPF PF01823.19 CDJ51853.1 - 0.021 14.9 0.1 0.031 14.4 0.1 1.2 1 0 0 1 1 1 0 MAC/Perforin domain Endomucin PF07010.12 CDJ51854.1 - 2.6 8.0 6.4 2.3 8.1 5.6 1.3 1 1 0 1 1 1 0 Endomucin HSP70 PF00012.20 CDJ51855.1 - 1.3e-257 855.8 10.7 1.6e-257 855.6 10.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ51855.1 - 3e-19 69.0 1.2 3.2e-18 65.6 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CDJ51855.1 - 0.00062 20.1 2.9 0.53 10.7 0.1 3.8 3 2 0 3 3 3 2 Cell division protein FtsA Radial_spoke_3 PF06098.11 CDJ51855.1 - 0.0021 17.4 1.1 0.0044 16.4 1.1 1.5 1 0 0 1 1 1 1 Radial spoke protein 3 FGGY_C PF02782.16 CDJ51855.1 - 0.011 15.5 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CDJ51855.1 - 0.015 14.3 0.2 2.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF3813 PF12758.7 CDJ51855.1 - 0.025 14.9 0.7 1.3 9.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3813) SIKE PF05769.11 CDJ51855.1 - 0.49 10.3 4.5 0.11 12.4 0.7 1.8 2 0 0 2 2 2 0 SIKE family Presenilin PF01080.17 CDJ51857.1 - 0.21 10.3 35.8 0.26 10.0 35.8 1.3 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 CDJ51857.1 - 0.22 11.1 27.6 0.25 11.0 27.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Mitofilin PF09731.9 CDJ51857.1 - 1.4 7.7 35.2 1.6 7.5 35.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hid1 PF12722.7 CDJ51857.1 - 4.6 5.2 33.7 4.9 5.2 33.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 CDJ51857.1 - 8.2 3.4 34.5 9.2 3.2 34.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RskA PF10099.9 CDJ51858.1 - 0.045 14.0 0.9 0.045 14.0 0.9 2.9 1 1 1 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ51858.1 - 0.076 13.0 37.0 0.097 12.7 37.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GAGA_bind PF06217.12 CDJ51858.1 - 0.23 11.7 16.7 0.3 11.3 16.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2459 PF09601.10 CDJ51858.1 - 0.58 9.9 4.4 0.62 9.8 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2459) Hamartin PF04388.12 CDJ51858.1 - 3.6 6.1 21.9 4.5 5.8 21.9 1.0 1 0 0 1 1 1 0 Hamartin protein DUF572 PF04502.13 CDJ51858.1 - 4.7 6.7 25.0 7.1 6.1 25.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Baculo_F PF12259.8 CDJ51858.1 - 4.8 5.6 8.8 7.4 5.0 8.8 1.2 1 0 0 1 1 1 0 Baculovirus F protein AbLIM_anchor PF16182.5 CDJ51858.1 - 6.5 6.5 15.7 8.4 6.1 15.7 1.1 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM TFIIA PF03153.13 CDJ51859.1 - 2.6e-05 24.4 26.7 2.6e-05 24.4 26.7 8.7 3 2 5 8 8 8 1 Transcription factor IIA, alpha/beta subunit SpoIIE PF07228.12 CDJ51859.1 - 0.00073 19.5 1.4 0.031 14.2 0.0 4.0 5 0 0 5 5 5 2 Stage II sporulation protein E (SpoIIE) Pex24p PF06398.11 CDJ51859.1 - 0.031 13.3 0.1 0.031 13.3 0.1 2.5 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin SR-25 PF10500.9 CDJ51860.1 - 7e-05 22.5 33.7 7e-05 22.5 33.7 2.0 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein SOBP PF15279.6 CDJ51860.1 - 1.4 9.5 33.2 2 9.0 33.2 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Zip PF02535.22 CDJ51860.1 - 2.9 7.0 11.4 4 6.6 11.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.9 CDJ51860.1 - 3.2 5.9 38.6 3.5 5.8 38.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PA26 PF04636.13 CDJ51860.1 - 4.1 6.2 14.5 5.5 5.8 14.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TMEM174 PF15029.6 CDJ51860.1 - 6.6 6.4 15.5 13 5.4 15.5 1.5 1 0 0 1 1 1 0 Transmembrane protein 174 SBE2 PF17076.5 CDJ51860.1 - 9.4 4.3 15.1 9.5 4.3 15.1 1.0 1 0 0 1 1 1 0 SBE2, cell-wall formation V_ATPase_I PF01496.19 CDJ51860.1 - 9.7 4.0 13.7 13 3.5 13.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Abhydrolase_6 PF12697.7 CDJ51861.1 - 2.6e-08 34.7 0.9 1.1e-07 32.7 0.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ51861.1 - 1.3e-06 27.8 0.3 2.8e-06 26.8 0.3 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ51861.1 - 0.00022 21.0 1.9 0.00072 19.3 0.6 2.2 2 1 1 3 3 3 1 alpha/beta hydrolase fold SR-25 PF10500.9 CDJ51861.1 - 0.066 12.8 12.9 0.095 12.3 12.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1631 PF07793.11 CDJ51861.1 - 0.34 9.3 8.6 0.45 8.9 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF4692 PF15763.5 CDJ51861.1 - 0.92 10.0 5.9 1.6 9.2 5.9 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF755 PF05501.11 CDJ51861.1 - 4.9 7.5 16.0 10 6.4 16.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Spt20 PF12090.8 CDJ51862.1 - 0.0012 18.5 8.4 0.0013 18.4 8.4 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ51862.1 - 0.02 13.9 7.8 0.022 13.8 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FTZ PF03867.14 CDJ51862.1 - 0.059 12.9 4.0 0.074 12.6 4.0 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Holin_2-3 PF13272.6 CDJ51862.1 - 0.068 13.5 0.2 0.1 12.9 0.2 1.3 1 0 0 1 1 1 0 Putative 2/3 transmembrane domain holin TFIIA PF03153.13 CDJ51862.1 - 0.13 12.2 13.9 0.17 11.8 13.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_UL32 PF06070.11 CDJ51862.1 - 0.6 7.8 5.4 0.72 7.5 5.4 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Pex14_N PF04695.13 CDJ51862.1 - 2.8 8.6 11.9 1.4 9.6 9.9 1.5 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF755 PF05501.11 CDJ51863.1 - 0.0081 16.4 20.0 0.0081 16.4 20.0 11.9 9 2 2 11 11 11 1 Domain of unknown function (DUF755) Na_Ala_symp PF01235.17 CDJ51863.1 - 0.092 12.0 0.3 0.19 11.0 0.3 1.5 1 0 0 1 1 1 0 Sodium:alanine symporter family RskA PF10099.9 CDJ51863.1 - 0.12 12.6 0.0 0.12 12.6 0.0 10.9 3 2 5 8 8 8 0 Anti-sigma-K factor rskA tRNA-synt_2b PF00587.25 CDJ51864.1 - 2e-23 83.3 0.0 4.3e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 CDJ51864.1 - 8.5e-20 71.1 0.0 1.5e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain ProRS-C_1 PF09180.11 CDJ51864.1 - 1.8e-19 69.7 0.1 4.6e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 CDJ51864.1 - 2.2e-19 69.4 0.0 3.6e-18 65.5 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain Cas_Cas1 PF01867.16 CDJ51864.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas1 AP2 PF00847.20 CDJ51865.1 - 2.3e-06 27.8 1.1 0.0074 16.5 0.7 2.4 2 0 0 2 2 2 2 AP2 domain K_channel_TID PF07941.11 CDJ51866.1 - 0.45 11.0 12.5 0.86 10.1 12.5 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Actin PF00022.19 CDJ51867.1 - 1.8e-07 30.2 7.4 0.00048 18.8 7.0 2.7 2 1 0 2 2 2 2 Actin PAT1 PF09770.9 CDJ51867.1 - 0.0015 16.9 21.1 0.0025 16.2 21.1 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 CDJ51867.1 - 0.0019 18.9 16.1 0.0019 18.9 16.1 2.7 3 0 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CSG2 PF16965.5 CDJ51867.1 - 0.0098 14.9 0.8 0.0098 14.9 0.8 1.7 2 0 0 2 2 1 1 Ceramide synthase regulator Ctr PF04145.15 CDJ51867.1 - 0.026 15.1 3.8 0.57 10.8 2.8 2.4 2 0 0 2 2 2 0 Ctr copper transporter family RPA43_OB PF17875.1 CDJ51867.1 - 0.03 14.9 3.9 0.065 13.9 3.9 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I OATP PF03137.20 CDJ51867.1 - 0.037 12.3 1.1 0.046 12.0 0.5 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CPSF100_C PF13299.6 CDJ51867.1 - 0.048 13.8 11.7 0.025 14.8 7.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EPL1 PF10513.9 CDJ51867.1 - 0.05 14.0 9.4 0.064 13.6 7.9 1.8 2 0 0 2 2 2 0 Enhancer of polycomb-like MecA PF05389.12 CDJ51867.1 - 0.053 13.2 8.1 0.11 12.1 8.1 1.5 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) CCDC53 PF10152.9 CDJ51867.1 - 0.1 13.0 15.0 0.2 12.1 11.9 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex LMBR1 PF04791.16 CDJ51867.1 - 0.18 10.7 1.5 0.23 10.3 1.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3405 PF11885.8 CDJ51867.1 - 0.18 10.4 9.3 0.25 9.9 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) DUF5520 PF17658.1 CDJ51867.1 - 0.19 10.8 8.1 0.28 10.3 8.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5520) Lin-8 PF03353.15 CDJ51867.1 - 0.2 11.2 20.3 0.74 9.3 16.4 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SpoIIP PF07454.11 CDJ51867.1 - 0.21 11.0 12.2 0.34 10.3 12.2 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 CDJ51867.1 - 0.24 10.1 7.7 0.4 9.4 7.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TCP PF03634.13 CDJ51867.1 - 0.25 11.9 12.9 0.98 10.0 9.6 2.1 2 0 0 2 2 2 0 TCP family transcription factor Velvet PF11754.8 CDJ51867.1 - 0.33 10.9 12.7 0.41 10.6 8.0 2.1 2 0 0 2 2 2 0 Velvet factor MMR1 PF08505.10 CDJ51867.1 - 0.33 11.2 20.4 0.18 12.1 14.2 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Pap_E4 PF02711.14 CDJ51867.1 - 0.49 11.4 15.3 1.9 9.5 9.3 2.3 2 0 0 2 2 2 0 E4 protein Mlh1_C PF16413.5 CDJ51867.1 - 0.75 9.1 11.8 0.18 11.2 8.4 1.7 2 0 0 2 2 1 0 DNA mismatch repair protein Mlh1 C-terminus SR-25 PF10500.9 CDJ51867.1 - 0.75 9.4 29.1 1.5 8.4 16.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EIIBC-GUT_N PF03612.14 CDJ51867.1 - 0.81 9.4 10.8 1.8 8.3 10.8 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2126 PF09899.9 CDJ51867.1 - 0.89 7.5 6.4 1.1 7.2 6.4 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Connexin PF00029.19 CDJ51867.1 - 0.96 9.2 9.1 1.7 8.4 9.1 1.3 1 0 0 1 1 1 0 Connexin eIF-3_zeta PF05091.12 CDJ51867.1 - 1 8.3 15.4 1.3 7.9 15.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RNA_pol_Rbc25 PF08292.12 CDJ51867.1 - 1.3 9.3 9.9 3 8.1 9.9 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Sporozoite_P67 PF05642.11 CDJ51867.1 - 1.4 6.9 11.6 1.9 6.5 5.8 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DNA_pol3_a_NII PF11490.8 CDJ51867.1 - 1.4 8.8 22.8 2.3 8.1 22.8 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II RR_TM4-6 PF06459.12 CDJ51867.1 - 1.7 8.4 14.1 2.9 7.6 14.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ51867.1 - 1.7 7.6 13.1 2.8 6.9 13.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF1645 PF07816.11 CDJ51867.1 - 1.8 9.1 15.9 3.9 8.0 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF913 PF06025.12 CDJ51867.1 - 2.2 7.2 10.0 2.1 7.2 7.9 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Band_3_cyto PF07565.13 CDJ51867.1 - 2.2 8.0 11.3 3.5 7.4 10.0 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Spt20 PF12090.8 CDJ51867.1 - 2.5 7.7 39.8 0.033 13.8 32.3 1.7 2 0 0 2 2 1 0 Spt20 family DUF2722 PF10846.8 CDJ51867.1 - 2.6 6.9 31.7 0.03 13.3 22.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) HGTP_anticodon2 PF12745.7 CDJ51867.1 - 3 7.3 15.5 0.25 10.8 9.6 1.9 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs V_ATPase_I PF01496.19 CDJ51867.1 - 3.1 5.6 13.4 4.2 5.2 13.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3408 PF11888.8 CDJ51867.1 - 3.3 7.9 17.0 0.85 9.8 13.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Sec62 PF03839.16 CDJ51867.1 - 3.4 7.1 8.6 6.5 6.2 8.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 MPM1 PF17234.2 CDJ51867.1 - 4.3 7.6 17.7 0.4 10.9 11.0 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF4834 PF16118.5 CDJ51867.1 - 4.4 8.3 19.8 1.3 10.0 14.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4770 PF15994.5 CDJ51867.1 - 5.3 7.2 15.9 2.2 8.5 13.1 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4770) DUF1764 PF08576.10 CDJ51867.1 - 5.8 7.9 12.6 0.26 12.2 6.8 1.8 2 0 0 2 2 1 0 Eukaryotic protein of unknown function (DUF1764) FAM176 PF14851.6 CDJ51867.1 - 5.8 6.6 13.1 0.67 9.6 8.3 1.9 2 0 0 2 2 1 0 FAM176 family BES1_N PF05687.13 CDJ51867.1 - 6.8 7.1 12.2 8 6.8 3.2 2.5 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal Het-C PF07217.11 CDJ51867.1 - 7.1 5.0 11.3 9.7 4.6 11.3 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C SID-1_RNA_chan PF13965.6 CDJ51867.1 - 7.3 4.9 6.7 0.15 10.4 0.2 1.5 2 0 0 2 2 1 0 dsRNA-gated channel SID-1 Membralin PF09746.9 CDJ51867.1 - 7.4 5.5 8.3 11 4.9 8.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein BORG_CEP PF14957.6 CDJ51867.1 - 7.7 7.7 15.1 3.4 8.9 7.8 2.2 2 0 0 2 2 2 0 Cdc42 effector FAM150 PF15129.6 CDJ51867.1 - 9.4 6.4 11.1 13 5.9 10.1 1.9 2 0 0 2 2 1 0 FAM150 family DUF4045 PF13254.6 CDJ51868.1 - 7.6 6.1 46.5 11 5.5 46.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) UPF0564 PF10595.9 CDJ51869.1 - 0.00019 20.6 23.0 0.00026 20.2 23.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 Macoilin PF09726.9 CDJ51869.1 - 0.081 11.5 32.7 0.095 11.2 32.7 1.0 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 CDJ51869.1 - 0.25 10.7 23.1 0.3 10.4 23.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ51869.1 - 1.2 9.0 55.0 1.7 8.6 55.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 CDJ51869.1 - 2.7 6.6 31.6 3.4 6.2 31.6 1.1 1 0 0 1 1 1 0 Hamartin protein RAP1 PF07218.11 CDJ51869.1 - 4 5.6 11.3 5.3 5.2 11.3 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.13 CDJ51869.1 - 5.1 5.0 45.9 7.4 4.5 45.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FHIPEP PF00771.20 CDJ51869.1 - 5.5 5.3 14.7 7.8 4.8 14.7 1.2 1 0 0 1 1 1 0 FHIPEP family LAP1C PF05609.12 CDJ51869.1 - 7.9 5.4 29.6 12 4.9 29.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) EFG_II PF14492.6 CDJ51871.1 - 1.1e-11 44.7 0.0 2.4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU PF00009.27 CDJ51871.1 - 4.4e-08 32.9 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 CDJ51871.1 - 7.4e-06 25.8 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Cwf_Cwc_15 PF04889.12 CDJ51871.1 - 0.0017 18.1 2.6 0.0017 18.1 2.6 2.2 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 CDJ51871.1 - 0.008 15.8 11.5 0.008 15.8 11.5 4.7 5 0 0 5 5 5 2 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ51872.1 - 0.0025 17.5 15.6 0.0025 17.5 15.6 9.5 6 2 4 10 10 10 3 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ51872.1 - 0.004 16.2 8.6 0.004 16.2 8.6 9.7 8 1 1 9 9 9 4 Protein of unknown function (DUF2722) SPX PF03105.19 CDJ51872.1 - 0.0043 17.0 13.8 0.0043 17.0 13.8 6.2 5 1 2 7 7 7 1 SPX domain RNA_pol_Rbc25 PF08292.12 CDJ51873.1 - 7.7e-12 45.6 0.1 3.8e-08 33.6 0.0 2.7 2 1 0 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CDJ51873.1 - 2.9e-10 40.4 0.1 7e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF3108 PF11306.8 CDJ51873.1 - 0.62 10.0 3.2 0.95 9.4 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) Hc1 PF07432.13 CDJ51873.1 - 7 7.0 13.1 12 6.3 13.1 1.3 1 0 0 1 1 1 0 Histone H1-like protein Hc1 DUF4757 PF15949.5 CDJ51875.1 - 0.27 11.7 0.1 0.27 11.7 0.1 5.2 3 2 1 4 4 4 0 Domain of unknown function (DUF4757) INSIG PF07281.12 CDJ51876.1 - 0.031 13.9 5.9 0.15 11.7 0.0 3.4 4 0 0 4 4 4 0 Insulin-induced protein (INSIG) Activator_LAG-3 PF11498.8 CDJ51878.1 - 0.00059 18.9 13.5 0.00059 18.9 13.5 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ51878.1 - 0.0051 16.9 19.9 0.0063 16.6 19.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ig_5 PF16681.5 CDJ51878.1 - 0.24 11.8 4.0 0.4 11.1 4.0 1.3 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Spt20 PF12090.8 CDJ51878.1 - 0.25 10.9 21.0 0.44 10.1 21.0 1.4 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 CDJ51878.1 - 0.34 9.8 9.5 0.39 9.7 9.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 CDJ51878.1 - 0.93 8.9 8.3 0.6 9.5 6.9 1.3 1 1 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Myc_N PF01056.18 CDJ51878.1 - 1.6 8.5 8.0 2 8.2 8.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF2722 PF10846.8 CDJ51878.1 - 2.4 7.0 18.3 4 6.3 18.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ51878.1 - 2.5 6.7 28.6 2.9 6.5 28.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ndc1_Nup PF09531.10 CDJ51878.1 - 2.7 6.6 10.8 3 6.4 10.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ51878.1 - 2.7 6.6 10.3 3.2 6.4 10.3 1.1 1 0 0 1 1 1 0 Presenilin UPF0524 PF15823.5 CDJ51878.1 - 3.5 6.9 8.3 0.71 9.2 4.9 1.5 2 0 0 2 2 2 0 UPF0524 of C3orf70 tRNA_synt_1c_R2 PF04557.15 CDJ51878.1 - 7.3 7.6 10.2 10 7.1 1.5 2.3 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF4834 PF16118.5 CDJ51878.1 - 7.8 7.5 9.3 2.2 9.3 6.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RMMBL PF07521.12 CDJ51881.1 - 2.8e-16 59.2 0.0 9.3e-16 57.5 0.0 1.9 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 CDJ51881.1 - 3.7e-09 36.9 0.0 3.7e-09 36.9 0.0 2.9 3 1 0 3 3 3 1 Beta-Casp domain BUD22 PF09073.10 CDJ51881.1 - 0.00092 18.7 8.1 0.00092 18.7 8.1 3.3 1 1 1 3 3 3 1 BUD22 CPSF73-100_C PF11718.8 CDJ51881.1 - 1.2 8.7 33.8 0.0072 15.9 12.5 4.9 1 1 1 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Acetyltransf_7 PF13508.7 CDJ51882.1 - 9.2e-05 22.8 0.0 0.0002 21.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ51882.1 - 0.00033 20.9 0.0 0.00092 19.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ51882.1 - 0.0076 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CCSMST1 PF15013.6 CDJ51882.1 - 0.098 12.8 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 CCSMST1 family LAP1C PF05609.12 CDJ51882.1 - 0.99 8.4 13.4 0.97 8.4 4.6 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 CDJ51882.1 - 3.9 6.1 9.2 1 8.1 1.7 2.1 2 0 0 2 2 2 0 Presenilin TFIIA PF03153.13 CDJ51883.1 - 0.0012 18.9 17.7 0.0015 18.6 17.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit HemX PF04375.14 CDJ51883.1 - 0.096 12.0 15.0 0.15 11.3 15.0 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spt20 PF12090.8 CDJ51883.1 - 0.13 11.9 16.0 0.24 11.0 16.0 1.5 1 0 0 1 1 1 0 Spt20 family E7 PF00527.18 CDJ51883.1 - 0.36 11.0 5.1 1.2 9.3 0.1 2.6 2 0 0 2 2 2 0 E7 protein, Early protein Ribosomal_60s PF00428.19 CDJ51883.1 - 6.6 7.4 43.8 3.2 8.4 6.6 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Cyto_heme_lyase PF01265.17 CDJ51885.1 - 1.8e-39 136.1 1.3 4.6e-38 131.5 1.3 2.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF3824 PF12868.7 CDJ51885.1 - 0.066 13.9 1.7 0.1 13.3 1.7 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) SR-25 PF10500.9 CDJ51886.1 - 4.7e-05 23.1 26.6 5.6e-05 22.9 26.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ51886.1 - 0.00046 20.4 25.7 0.00046 20.4 25.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF755) PI3K_1B_p101 PF10486.9 CDJ51886.1 - 0.098 10.4 16.5 0.12 10.1 16.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Glu_synthase PF01645.17 CDJ51886.1 - 0.67 9.0 10.1 0.68 9.0 9.4 1.3 1 1 0 1 1 1 0 Conserved region in glutamate synthase MID_MedPIWI PF18296.1 CDJ51886.1 - 1.1 9.0 25.7 1.2 8.8 25.7 1.0 1 0 0 1 1 1 0 MID domain of medPIWI Macoilin PF09726.9 CDJ51886.1 - 1.4 7.4 26.2 1.7 7.1 26.2 1.1 1 0 0 1 1 1 0 Macoilin family IMUP PF15761.5 CDJ51886.1 - 3.4 8.4 16.0 6.4 7.5 16.0 1.5 1 1 0 1 1 1 0 Immortalisation up-regulated protein dsRBD2 PF17842.1 CDJ51886.1 - 4.6 7.4 21.4 0.045 14.0 8.1 2.2 1 1 1 2 2 2 0 Double-stranded RNA binding domain 2 Ribosomal_L7Ae PF01248.26 CDJ51888.1 - 4.4e-27 93.7 0.4 5.5e-27 93.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 CDJ51888.1 - 0.016 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding DREPP PF05558.12 CDJ51889.1 - 0.0029 17.5 2.3 0.0042 17.0 2.3 1.2 1 0 0 1 1 1 1 DREPP plasma membrane polypeptide Roughex PF06020.11 CDJ51889.1 - 0.022 13.9 3.3 0.026 13.6 3.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PrgI PF12666.7 CDJ51889.1 - 0.033 14.9 1.5 4.6 8.0 3.3 2.3 2 0 0 2 2 2 0 PrgI family protein Sre PF03125.18 CDJ51889.1 - 0.044 12.9 0.4 0.8 8.8 0.0 2.1 2 0 0 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor Pkinase_C PF00433.24 CDJ51889.1 - 0.048 14.4 0.1 0.076 13.7 0.1 1.6 1 1 0 1 1 1 0 Protein kinase C terminal domain FAM176 PF14851.6 CDJ51889.1 - 0.075 12.7 9.8 0.027 14.1 6.7 1.8 1 1 1 2 2 2 0 FAM176 family LapA_dom PF06305.11 CDJ51889.1 - 0.11 12.3 0.0 0.11 12.3 0.0 3.4 3 0 0 3 3 2 0 Lipopolysaccharide assembly protein A domain V_ATPase_I PF01496.19 CDJ51889.1 - 0.13 10.1 7.2 0.2 9.6 7.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family O-antigen_lig PF13425.6 CDJ51889.1 - 0.17 10.6 0.0 0.17 10.6 0.0 1.5 2 0 0 2 2 2 0 O-antigen ligase like membrane protein DUF913 PF06025.12 CDJ51889.1 - 0.3 10.0 3.8 0.35 9.8 3.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.6 CDJ51889.1 - 0.47 8.8 2.7 0.6 8.5 2.6 1.2 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 CDJ51889.1 - 2.8 6.9 7.2 0.064 12.3 0.6 1.6 2 0 0 2 2 2 0 CLN3 protein Connexin PF00029.19 CDJ51889.1 - 3.2 7.4 9.2 5.7 6.6 9.2 1.4 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ51889.1 - 7.9 5.1 19.4 9.6 4.8 0.4 2.1 2 0 0 2 2 2 0 Presenilin TMEMspv1-c74-12 PF11044.8 CDJ51889.1 - 9.5 6.3 5.7 1.9 8.6 0.4 2.5 2 1 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein TT_ORF1 PF02956.14 CDJ51890.1 - 0.011 14.5 0.2 0.013 14.2 0.2 1.1 1 0 0 1 1 1 0 TT viral orf 1 EPL1 PF10513.9 CDJ51890.1 - 0.17 12.3 5.7 0.24 11.8 5.7 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like PSD5 PF07637.11 CDJ51890.1 - 0.24 11.8 4.6 0.26 11.7 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) Miga PF10265.9 CDJ51890.1 - 1.1 8.1 7.1 1.3 7.9 7.1 1.0 1 0 0 1 1 1 0 Mitoguardin PAT1 PF09770.9 CDJ51890.1 - 3.1 5.9 19.5 3.9 5.6 19.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bud13 PF09736.9 CDJ51890.1 - 3.5 8.0 11.1 1.3 9.4 7.7 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Neur_chan_memb PF02932.16 CDJ51890.1 - 3.7 7.6 8.9 4.9 7.1 8.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 CDJ51890.1 - 5 6.0 11.0 6.4 5.6 11.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ51891.1 - 2.2e-06 28.6 21.9 0.02 15.8 0.0 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF4834) Apt1 PF10351.9 CDJ51891.1 - 0.0025 16.7 2.4 0.0025 16.7 2.4 2.0 2 0 0 2 2 2 1 Golgi-body localisation protein domain RSN1_TM PF13967.6 CDJ51891.1 - 0.003 17.3 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 2 Late exocytosis, associated with Golgi transport Plasmodium_Vir PF05795.11 CDJ51891.1 - 0.014 14.9 0.2 0.014 14.9 0.2 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein MecA PF05389.12 CDJ51891.1 - 0.036 13.7 4.6 2.2 7.9 0.2 2.5 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) SPX PF03105.19 CDJ51891.1 - 0.043 13.7 21.7 0.7 9.7 18.5 2.7 1 1 2 3 3 2 0 SPX domain HemY_N PF07219.13 CDJ51891.1 - 0.047 13.9 0.3 0.047 13.9 0.3 7.4 6 2 2 8 8 4 0 HemY protein N-terminus FHIPEP PF00771.20 CDJ51891.1 - 0.078 11.4 7.9 3.1 6.2 0.3 3.3 3 0 0 3 3 3 0 FHIPEP family Pex24p PF06398.11 CDJ51891.1 - 0.14 11.1 0.0 0.36 9.8 0.0 1.6 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin SID-1_RNA_chan PF13965.6 CDJ51891.1 - 0.3 9.5 0.0 28 2.9 0.0 2.8 3 0 0 3 3 3 0 dsRNA-gated channel SID-1 Spt20 PF12090.8 CDJ51891.1 - 0.38 10.3 61.3 1.5 8.4 20.6 3.5 3 1 0 3 3 3 0 Spt20 family CLN3 PF02487.17 CDJ51891.1 - 0.45 9.5 5.7 3.8 6.5 0.3 3.1 4 0 0 4 4 4 0 CLN3 protein Connexin PF00029.19 CDJ51891.1 - 0.65 9.7 7.5 6.9 6.4 0.4 2.7 2 0 0 2 2 2 0 Connexin Tmemb_9 PF05434.11 CDJ51891.1 - 1.4 8.8 0.0 1.4 8.8 0.0 3.9 4 0 0 4 4 4 0 TMEM9 Peroxin-13_N PF04088.13 CDJ51891.1 - 1.5 9.1 7.4 10 6.4 0.7 3.7 4 0 0 4 4 4 0 Peroxin 13, N-terminal region BAF1_ABF1 PF04684.13 CDJ51891.1 - 1.9 7.4 0.0 1.9 7.4 0.0 3.6 3 1 0 3 3 2 0 BAF1 / ABF1 chromatin reorganising factor TRAP_alpha PF03896.16 CDJ51891.1 - 2.5 7.2 12.6 9.6 5.3 3.3 3.6 4 0 0 4 4 4 0 Translocon-associated protein (TRAP), alpha subunit EOS1 PF12326.8 CDJ51891.1 - 3.5 7.5 6.6 6.7 6.6 0.6 2.8 2 2 0 2 2 2 0 N-glycosylation protein DUF4820 PF16091.5 CDJ51891.1 - 5.5 6.3 18.0 4.3 6.6 3.9 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4820) zf-LITAF-like PF10601.9 CDJ51891.1 - 5.7 7.3 16.1 0.53 10.6 8.0 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain V_ATPase_I PF01496.19 CDJ51891.1 - 8.4 4.2 19.4 30 2.4 0.0 3.9 4 0 0 4 4 4 0 V-type ATPase 116kDa subunit family zf-CCCH_4 PF18044.1 CDJ51893.1 - 0.00037 20.2 2.9 0.00057 19.6 2.9 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CDJ51893.1 - 0.024 15.3 10.0 0.024 15.3 10.0 2.5 1 1 1 2 2 2 0 Torus domain zf-CCCH PF00642.24 CDJ51893.1 - 0.045 13.7 8.0 0.17 11.9 2.7 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4127 PF13552.6 CDJ51893.1 - 0.11 11.1 0.2 0.11 11.1 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4127) Ndc1_Nup PF09531.10 CDJ51893.1 - 0.23 10.1 1.4 0.19 10.4 1.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex14_N PF04695.13 CDJ51893.1 - 0.26 11.9 14.8 0.042 14.5 9.1 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf_CCCH_4 PF18345.1 CDJ51893.1 - 0.28 11.3 4.9 0.45 10.7 3.9 1.9 1 1 1 2 2 2 0 Zinc finger domain TFIIA PF03153.13 CDJ51893.1 - 0.7 9.8 20.9 0.87 9.5 20.9 1.2 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4770 PF15994.5 CDJ51893.1 - 0.7 10.1 10.0 2.6 8.2 5.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Spt20 PF12090.8 CDJ51893.1 - 0.92 9.1 26.9 1.7 8.2 26.9 1.5 1 1 0 1 1 1 0 Spt20 family CCDC53 PF10152.9 CDJ51893.1 - 1.8 9.0 10.7 1 9.8 7.3 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Med3 PF11593.8 CDJ51893.1 - 2.9 7.0 12.8 4 6.5 12.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal UPF0560 PF10577.9 CDJ51893.1 - 3.6 6.0 9.5 5.7 5.3 9.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3408 PF11888.8 CDJ51893.1 - 5.8 7.1 16.9 1.9 8.6 7.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) RR_TM4-6 PF06459.12 CDJ51893.1 - 8.1 6.2 13.0 6.3 6.5 5.3 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4834 PF16118.5 CDJ51893.1 - 8.5 7.4 15.7 4.7 8.2 7.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ORC_WH_C PF18137.1 CDJ51893.1 - 9 6.4 16.6 2.2 8.4 3.4 2.1 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF5327 PF17261.2 CDJ51893.1 - 9 7.1 16.0 1.6 9.5 10.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF4259 PF14078.6 CDJ51895.1 - 0.29 11.9 9.2 1.1 10.0 2.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4259) DDHD PF02862.17 CDJ51896.1 - 0.00025 21.3 3.9 0.00025 21.3 3.9 1.1 1 0 0 1 1 1 1 DDHD domain SpoIIP PF07454.11 CDJ51896.1 - 0.00062 19.3 7.7 0.00062 19.3 7.7 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DUF5308 PF17233.2 CDJ51896.1 - 0.0024 18.1 4.2 0.0025 18.1 4.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5308) TFIIA PF03153.13 CDJ51896.1 - 0.0032 17.5 28.5 0.0038 17.3 28.5 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FAM91_C PF14648.6 CDJ51896.1 - 0.016 14.0 3.5 0.021 13.7 3.5 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Tim54 PF11711.8 CDJ51896.1 - 0.042 12.6 10.2 0.049 12.4 10.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 CDJ51896.1 - 0.06 12.6 2.3 0.058 12.6 2.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NST1 PF13945.6 CDJ51896.1 - 0.083 13.0 20.0 0.11 12.6 20.0 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator UPF0565 PF10561.9 CDJ51896.1 - 0.21 10.8 4.6 0.21 10.7 4.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 EOS1 PF12326.8 CDJ51896.1 - 0.35 10.8 9.2 0.43 10.5 9.2 1.1 1 0 0 1 1 1 0 N-glycosylation protein MCM_bind PF09739.9 CDJ51896.1 - 0.36 9.2 12.5 0.4 9.1 12.5 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Lin-8 PF03353.15 CDJ51896.1 - 0.48 9.9 18.5 0.52 9.8 18.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4050 PF13259.6 CDJ51896.1 - 0.5 10.7 14.5 0.67 10.3 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF913 PF06025.12 CDJ51896.1 - 0.53 9.2 10.8 0.64 8.9 10.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PepSY_TM PF03929.16 CDJ51896.1 - 0.6 9.7 4.7 0.74 9.4 4.7 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Hydin_ADK PF17213.3 CDJ51896.1 - 0.64 10.3 13.5 0.83 9.9 13.5 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain HCO3_cotransp PF00955.21 CDJ51896.1 - 0.76 8.5 8.9 0.87 8.3 8.9 1.0 1 0 0 1 1 1 0 HCO3- transporter family Presenilin PF01080.17 CDJ51896.1 - 0.95 8.2 21.0 1.1 7.9 21.0 1.1 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 CDJ51896.1 - 1.3 8.4 12.0 1.6 8.2 12.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2370 PF10176.9 CDJ51896.1 - 1.4 8.5 8.0 1.7 8.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) NPR3 PF03666.13 CDJ51896.1 - 1.4 7.6 15.7 1.7 7.3 15.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PEHE PF15275.6 CDJ51896.1 - 1.4 9.5 15.2 2.2 8.9 15.2 1.3 1 0 0 1 1 1 0 PEHE domain Eapp_C PF10238.9 CDJ51896.1 - 1.5 8.9 20.1 2 8.5 20.1 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein FAM60A PF15396.6 CDJ51896.1 - 1.7 8.6 13.3 2.1 8.3 13.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.9 CDJ51896.1 - 1.8 6.7 26.2 1.9 6.6 26.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 CDJ51896.1 - 1.9 7.1 11.4 2.2 6.9 11.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Connexin PF00029.19 CDJ51896.1 - 2 8.1 14.3 2.5 7.8 14.3 1.1 1 0 0 1 1 1 0 Connexin DUF3112 PF11309.8 CDJ51896.1 - 2.1 7.8 5.1 2.6 7.4 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) GREB1 PF15782.5 CDJ51896.1 - 2.2 5.3 14.1 2.3 5.2 14.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Rrn6 PF10214.9 CDJ51896.1 - 2.5 6.5 25.1 2.7 6.4 25.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CCDC53 PF10152.9 CDJ51896.1 - 2.5 8.5 19.9 3.6 8.0 19.9 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex BORG_CEP PF14957.6 CDJ51896.1 - 2.8 9.1 9.4 4 8.6 9.4 1.2 1 0 0 1 1 1 0 Cdc42 effector DUF908 PF06012.12 CDJ51896.1 - 3 7.2 16.8 3.7 6.9 16.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Gti1_Pac2 PF09729.9 CDJ51896.1 - 3.3 7.8 15.3 4.3 7.4 15.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Pex14_N PF04695.13 CDJ51896.1 - 3.6 8.2 28.3 5.3 7.7 28.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Otopetrin PF03189.13 CDJ51896.1 - 4.6 6.0 11.8 4.9 5.8 11.8 1.0 1 0 0 1 1 1 0 Otopetrin DUF3295 PF11702.8 CDJ51896.1 - 4.9 6.4 18.2 6.2 6.1 18.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) MMPL PF03176.15 CDJ51896.1 - 5.4 5.8 6.2 6.4 5.6 6.2 1.1 1 0 0 1 1 1 0 MMPL family Afi1 PF07792.12 CDJ51896.1 - 5.7 7.4 16.6 7.8 7.0 16.6 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4569 PF15133.6 CDJ51896.1 - 6.1 6.5 18.8 7.1 6.3 18.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF5523 PF17661.1 CDJ51896.1 - 6.2 6.4 18.8 8 6.1 18.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) SLC12 PF03522.15 CDJ51896.1 - 6.5 5.7 17.8 7.2 5.5 17.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DAG_kinase_N PF14513.6 CDJ51896.1 - 6.8 6.9 19.0 8.3 6.6 19.0 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF3464 PF11947.8 CDJ51896.1 - 6.9 6.4 17.2 12 5.6 17.2 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CPSF100_C PF13299.6 CDJ51896.1 - 7.5 6.7 16.0 10 6.3 16.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.19 CDJ51896.1 - 7.6 4.3 19.3 8.1 4.2 19.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 CDJ51896.1 - 7.9 4.6 16.5 9.8 4.3 16.5 1.0 1 0 0 1 1 1 0 CDC45-like protein PRC2_HTH_1 PF18118.1 CDJ51896.1 - 8 7.3 13.5 13 6.7 13.5 1.2 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Chromo PF00385.24 CDJ51897.1 - 0.0063 16.4 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF913 PF06025.12 CDJ51897.1 - 0.65 8.9 7.5 1.1 8.2 7.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mem_trans PF03547.18 CDJ51897.1 - 4.8 5.5 6.0 8 4.7 6.0 1.3 1 0 0 1 1 1 0 Membrane transport protein Suf PF05843.14 CDJ51897.1 - 5.6 6.9 10.5 10 6.0 10.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-RING_11 PF17123.5 CDJ51898.1 - 0.00069 19.3 1.7 0.0017 18.0 1.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CDJ51898.1 - 0.00098 19.4 3.3 0.0021 18.4 3.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ51898.1 - 0.012 15.7 6.6 0.025 14.6 6.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CDJ51898.1 - 0.019 14.6 0.6 0.035 13.7 0.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CDJ51898.1 - 0.054 13.4 3.4 0.13 12.1 3.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ51898.1 - 0.063 13.3 1.8 0.13 12.3 1.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain KxDL PF10241.9 CDJ51898.1 - 0.072 13.4 0.4 0.072 13.4 0.4 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein Prok-RING_1 PF14446.6 CDJ51898.1 - 0.22 11.5 5.1 0.46 10.5 5.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TolA_bind_tri PF16331.5 CDJ51898.1 - 0.27 11.4 5.7 0.51 10.5 1.2 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation GIT_CC PF16559.5 CDJ51898.1 - 0.27 11.1 5.2 0.71 9.8 0.1 3.1 2 2 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4472 PF14739.6 CDJ51898.1 - 2.3 9.0 7.8 2.1 9.1 0.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) LCAT PF02450.15 CDJ51899.1 - 5.2e-24 85.1 0.1 8.6e-18 64.7 0.0 3.2 2 1 1 3 3 3 3 Lecithin:cholesterol acyltransferase RPN1_RPN2_N PF17781.1 CDJ51899.1 - 0.087 12.2 0.4 0.13 11.6 0.4 1.2 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Pkinase PF00069.25 CDJ51900.1 - 1.5e-17 63.9 0.1 1.6e-14 53.9 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ51900.1 - 1.1e-09 37.9 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ51900.1 - 0.0082 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ51900.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_methylase PF00145.17 CDJ51901.1 - 6.3e-36 124.4 0.1 1.8e-34 119.6 0.1 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase CLN3 PF02487.17 CDJ51901.1 - 0.071 12.1 0.9 0.11 11.5 0.9 1.2 1 0 0 1 1 1 0 CLN3 protein V_ATPase_I PF01496.19 CDJ51901.1 - 0.77 7.6 7.0 1.1 7.1 7.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TERB2 PF15101.6 CDJ51901.1 - 5.6 7.0 14.4 30 4.6 14.7 2.0 1 1 1 2 2 2 0 Telomere-associated protein TERB2 GAS PF13851.6 CDJ51902.1 - 1.9e-07 30.6 18.0 1.9e-07 30.6 18.0 3.4 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding DUF4854 PF16146.5 CDJ51902.1 - 2.1 8.7 9.0 0.6 10.5 3.4 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4854) HisKA_3 PF07730.13 CDJ51902.1 - 5.2 7.7 20.9 2.5 8.7 1.2 5.7 3 2 3 6 6 6 0 Histidine kinase BSP_II PF05432.11 CDJ51903.1 - 0.092 12.4 10.0 0.11 12.2 10.0 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Paf1 PF03985.13 CDJ51903.1 - 0.99 8.3 5.6 1.1 8.2 5.6 1.1 1 0 0 1 1 1 0 Paf1 NDUF_B12 PF08122.12 CDJ51903.1 - 2.4 8.3 0.0 2.4 8.3 0.0 2.5 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family GRP PF07172.11 CDJ51903.1 - 3.3 8.5 17.6 2.8 8.7 16.6 1.4 1 1 0 1 1 1 0 Glycine rich protein family SRP-alpha_N PF04086.13 CDJ51903.1 - 4.5 7.1 9.7 5.4 6.9 9.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Plasmodium_Vir PF05795.11 CDJ51903.1 - 4.6 6.6 6.6 5.1 6.4 6.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 CDJ51903.1 - 5 5.8 6.3 6 5.5 6.3 1.0 1 0 0 1 1 1 0 Presenilin Atrophin-1 PF03154.15 CDJ51903.1 - 8.3 4.5 16.8 8.4 4.5 16.4 1.3 1 1 0 1 1 1 0 Atrophin-1 family DUF4179 PF13786.6 CDJ51905.1 - 0.038 14.5 6.5 1.4 9.4 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) Lin-8 PF03353.15 CDJ51905.1 - 0.83 9.2 7.9 0.92 9.0 7.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1697 PF08002.11 CDJ51905.1 - 1.9 8.9 6.2 0.63 10.5 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1697) GCP_N_terminal PF17681.1 CDJ51906.1 - 6.7e-11 42.4 0.2 6.7e-11 42.4 0.2 2.5 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal TFIIA PF03153.13 CDJ51906.1 - 2.4 8.1 40.9 0.021 14.9 17.2 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit IMUP PF15761.5 CDJ51906.1 - 3.1 8.5 5.9 31 5.3 1.8 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein RskA PF10099.9 CDJ51907.1 - 0.00021 21.7 9.6 0.00021 21.7 9.6 15.5 4 4 8 12 12 12 2 Anti-sigma-K factor rskA DUF1472 PF07339.12 CDJ51907.1 - 0.019 15.5 0.4 0.07 13.6 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1472) Spt20 PF12090.8 CDJ51909.1 - 0.011 15.4 18.4 0.011 15.4 18.4 3.6 3 1 1 4 4 4 0 Spt20 family FAM176 PF14851.6 CDJ51909.1 - 0.37 10.5 11.1 13 5.4 0.0 3.3 3 0 0 3 3 3 0 FAM176 family Presenilin PF01080.17 CDJ51909.1 - 1.6 7.4 23.8 0.16 10.7 18.2 2.0 2 0 0 2 2 2 0 Presenilin RskA PF10099.9 CDJ51910.1 - 0.027 14.8 15.8 0.037 14.3 15.8 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Neuregulin PF02158.15 CDJ51910.1 - 0.039 13.3 7.1 0.041 13.2 7.1 1.0 1 0 0 1 1 1 0 Neuregulin intracellular region Spt20 PF12090.8 CDJ51910.1 - 0.22 11.1 25.9 0.24 11.0 25.9 1.2 1 0 0 1 1 1 0 Spt20 family DUF2232 PF09991.9 CDJ51910.1 - 0.47 9.6 3.9 0.51 9.5 3.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) NEMP PF10225.9 CDJ51910.1 - 0.58 9.8 2.9 0.62 9.7 2.9 1.0 1 0 0 1 1 1 0 NEMP family DUF4834 PF16118.5 CDJ51910.1 - 0.61 11.1 7.3 0.66 11.0 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Peptidase_S15 PF02129.18 CDJ51910.1 - 0.63 9.6 9.4 0.67 9.5 9.4 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Activator_LAG-3 PF11498.8 CDJ51910.1 - 0.65 8.9 34.1 0.67 8.9 34.1 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Presenilin PF01080.17 CDJ51910.1 - 0.68 8.6 5.5 0.69 8.6 5.5 1.2 1 0 0 1 1 1 0 Presenilin DUF4630 PF15443.6 CDJ51910.1 - 0.75 10.0 10.9 0.89 9.7 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) R_equi_Vir PF05526.11 CDJ51910.1 - 1.2 9.0 8.3 1.4 8.8 8.3 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein TFIIA PF03153.13 CDJ51910.1 - 1.4 8.8 30.0 1.5 8.7 30.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ51910.1 - 1.5 8.7 11.7 1.4 8.9 11.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM199X PF15814.5 CDJ51910.1 - 1.9 7.4 5.1 2.4 7.1 5.1 1.0 1 0 0 1 1 1 0 Protein family FAM199X Usp PF00582.26 CDJ51910.1 - 6.3 7.3 8.3 7.4 7.1 8.3 1.1 1 0 0 1 1 1 0 Universal stress protein family MCR_alpha PF02249.17 CDJ51910.1 - 8.9 6.8 8.9 0.67 10.4 4.4 1.4 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain TraT PF05818.12 CDJ51911.1 - 0.0075 16.0 5.1 0.0093 15.7 5.1 1.1 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein DUF3827 PF12877.7 CDJ51911.1 - 0.051 11.9 7.6 0.048 12.1 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) RskA PF10099.9 CDJ51911.1 - 0.057 13.7 14.2 0.072 13.4 14.2 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA RSRP PF17069.5 CDJ51911.1 - 0.061 12.9 17.2 0.069 12.7 17.2 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Apt1 PF10351.9 CDJ51911.1 - 0.19 10.5 7.1 0.17 10.7 7.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC24 PF15669.5 CDJ51911.1 - 0.26 11.1 6.9 0.28 11.0 6.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Ctr PF04145.15 CDJ51911.1 - 0.32 11.6 2.0 0.41 11.3 2.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family YbgS PF13985.6 CDJ51911.1 - 0.34 11.2 10.0 0.47 10.7 10.0 1.3 1 0 0 1 1 1 0 YbgS-like protein Bul1_C PF04426.12 CDJ51911.1 - 0.47 9.8 3.5 0.58 9.5 3.5 1.1 1 0 0 1 1 1 0 Bul1 C terminus PAP1 PF08601.10 CDJ51911.1 - 0.5 10.0 15.8 0.53 10.0 15.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 AF-4 PF05110.13 CDJ51911.1 - 0.78 7.8 18.4 0.84 7.7 18.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Secretin_N_2 PF07655.13 CDJ51911.1 - 1.1 9.8 17.0 1.5 9.4 17.0 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain SPX PF03105.19 CDJ51911.1 - 1.4 8.8 12.3 1.6 8.6 12.3 1.0 1 0 0 1 1 1 0 SPX domain DUF1635 PF07795.11 CDJ51911.1 - 3.3 7.5 10.0 4.5 7.1 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Corona_nucleoca PF00937.18 CDJ51911.1 - 3.3 6.6 15.3 3.8 6.4 15.3 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein TAF4 PF05236.14 CDJ51911.1 - 5.4 6.7 12.9 7.2 6.3 12.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF3438 PF11920.8 CDJ51912.1 - 0.65 9.2 7.7 0.68 9.1 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) FAM209 PF15206.6 CDJ51912.1 - 1.5 8.6 7.4 1.5 8.6 7.4 1.0 1 0 0 1 1 1 0 FAM209 family SRRM_C PF15230.6 CDJ51912.1 - 1.6 9.3 6.4 1.8 9.2 6.4 1.1 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus RAMP4 PF06624.12 CDJ51912.1 - 3 8.0 8.6 3.5 7.7 8.6 1.1 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 FTO_NTD PF12933.7 CDJ51912.1 - 6.5 5.9 11.3 6.7 5.9 11.3 1.0 1 0 0 1 1 1 0 FTO catalytic domain RNA_pol_Rbc25 PF08292.12 CDJ51912.1 - 7.2 6.9 10.2 6.9 6.9 10.2 1.0 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Presenilin PF01080.17 CDJ51912.1 - 8.9 5.0 13.1 9.2 4.9 13.1 1.0 1 0 0 1 1 1 0 Presenilin RAP1 PF07218.11 CDJ51913.1 - 0.55 8.5 5.4 0.65 8.2 5.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Adeno_PV PF03910.13 CDJ51914.1 - 0.015 14.0 3.6 0.022 13.5 3.6 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV RR_TM4-6 PF06459.12 CDJ51914.1 - 1.4 8.7 13.7 1.7 8.4 13.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CLN3 PF02487.17 CDJ51914.1 - 2.8 6.9 7.2 3.6 6.5 7.2 1.4 1 0 0 1 1 1 0 CLN3 protein SLC12 PF03522.15 CDJ51914.1 - 4.8 6.1 15.7 5.2 6.0 15.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RskA PF10099.9 CDJ51914.1 - 8.5 6.6 27.4 15 5.9 18.8 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Hydrolase PF00702.26 CDJ51915.1 - 0.00055 20.3 0.3 0.00055 20.3 0.3 2.9 2 2 1 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2722 PF10846.8 CDJ51915.1 - 0.0066 15.5 4.3 0.0066 15.5 4.3 4.4 2 1 2 4 4 4 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ51915.1 - 0.0083 15.8 12.1 0.0083 15.8 12.1 3.9 2 1 0 3 3 3 1 Spt20 family BPS1 PF05633.11 CDJ51915.1 - 1.2 8.1 11.6 0.21 10.6 2.6 2.6 2 0 0 2 2 2 0 Protein BYPASS1-related TFIIA PF03153.13 CDJ51916.1 - 0.8 9.6 10.9 0.91 9.5 10.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4775 PF16001.5 CDJ51917.1 - 1.1 8.6 18.1 1.2 8.5 18.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) HMG14_17 PF01101.18 CDJ51917.1 - 4.4 8.3 17.9 1.1 10.2 14.0 1.9 1 1 1 2 2 2 0 HMG14 and HMG17 MPP6 PF10175.9 CDJ51919.1 - 0.026 15.0 6.4 0.031 14.8 6.4 1.1 1 0 0 1 1 1 0 M-phase phosphoprotein 6 DUF2368 PF10166.9 CDJ51919.1 - 0.046 13.3 10.5 0.084 12.5 10.5 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Sporozoite_P67 PF05642.11 CDJ51919.1 - 0.081 11.0 1.7 0.09 10.8 1.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen EPL1 PF10513.9 CDJ51919.1 - 0.19 12.1 6.4 0.22 11.9 6.4 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DDHD PF02862.17 CDJ51919.1 - 0.4 10.8 4.4 0.44 10.7 4.4 1.2 1 0 0 1 1 1 0 DDHD domain DUF4342 PF14242.6 CDJ51919.1 - 0.51 10.4 0.0 0.51 10.4 0.0 3.1 2 1 0 2 2 1 0 Domain of unknown function (DUF4342) CDV3 PF15359.6 CDJ51919.1 - 0.58 10.6 12.5 0.73 10.3 12.5 1.1 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Spt20 PF12090.8 CDJ51919.1 - 0.73 9.4 24.5 0.86 9.2 24.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF4770 PF15994.5 CDJ51919.1 - 1.2 9.4 7.9 1.3 9.2 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Presenilin PF01080.17 CDJ51919.1 - 1.2 7.8 9.3 1.2 7.8 9.3 1.1 1 0 0 1 1 1 0 Presenilin UPF0524 PF15823.5 CDJ51919.1 - 1.4 8.3 5.9 1.9 7.8 5.9 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 TERB2 PF15101.6 CDJ51919.1 - 1.9 8.5 12.1 2.2 8.3 12.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Sec62 PF03839.16 CDJ51919.1 - 2.3 7.7 5.4 2.5 7.6 5.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 PAT1 PF09770.9 CDJ51919.1 - 2.8 6.1 18.0 2.8 6.1 18.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPATA3 PF15662.5 CDJ51919.1 - 2.8 8.5 11.5 3.3 8.3 11.5 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DUF4813 PF16072.5 CDJ51919.1 - 3.7 7.1 51.7 4.5 6.8 51.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) RLL PF10036.9 CDJ51919.1 - 3.8 7.3 13.1 5 6.9 13.1 1.2 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Neur_chan_memb PF02932.16 CDJ51919.1 - 4 7.4 5.4 4.1 7.4 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NUDE_C PF04880.13 CDJ51919.1 - 4.8 7.6 11.0 6.1 7.3 11.0 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Hid1 PF12722.7 CDJ51919.1 - 5.3 5.0 7.8 5 5.1 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EIIBC-GUT_N PF03612.14 CDJ51919.1 - 5.5 6.7 8.5 7.8 6.2 8.5 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RskA PF10099.9 CDJ51920.1 - 0.00017 21.9 3.0 0.00017 21.9 3.0 2.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ51920.1 - 0.011 16.3 4.2 0.011 16.3 4.2 1.7 1 1 1 2 2 2 0 60s Acidic ribosomal protein Nop53 PF07767.11 CDJ51920.1 - 0.027 13.9 22.1 0.03 13.7 22.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) STAC2_u1 PF16664.5 CDJ51920.1 - 0.031 14.7 15.8 0.043 14.3 15.8 1.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 SAGA-Tad1 PF12767.7 CDJ51920.1 - 0.038 13.7 16.9 0.047 13.4 16.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RR_TM4-6 PF06459.12 CDJ51920.1 - 0.31 10.8 15.7 0.32 10.8 15.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF572 PF04502.13 CDJ51920.1 - 0.34 10.5 16.0 0.35 10.5 16.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CCSAP PF15748.5 CDJ51920.1 - 0.5 10.5 24.4 0.7 10.0 24.4 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Dsh_C PF12316.8 CDJ51920.1 - 0.53 10.7 18.1 0.71 10.3 18.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TCP PF03634.13 CDJ51920.1 - 0.71 10.4 24.4 1 9.9 24.4 1.2 1 0 0 1 1 1 0 TCP family transcription factor Serinc PF03348.15 CDJ51920.1 - 1 8.2 8.0 1.1 8.1 8.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SR-25 PF10500.9 CDJ51920.1 - 1.9 8.1 29.3 13 5.3 29.2 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SprA-related PF12118.8 CDJ51920.1 - 2.4 7.2 37.7 3.2 6.8 37.7 1.3 1 0 0 1 1 1 0 SprA-related family Hid1 PF12722.7 CDJ51920.1 - 2.8 6.0 19.4 2.6 6.1 19.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 CDJ51920.1 - 3.1 4.8 22.2 3 4.8 22.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_23 PF13476.6 CDJ51920.1 - 3.5 8.1 19.9 1.5 9.3 18.1 1.3 2 0 0 2 2 1 0 AAA domain PAT1 PF09770.9 CDJ51920.1 - 4.1 5.6 28.9 4.2 5.5 28.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.19 CDJ51920.1 - 5.2 4.9 15.9 5.5 4.8 15.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S64 PF08192.11 CDJ51920.1 - 5.7 5.3 20.0 5.7 5.3 20.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3616 PF12275.8 CDJ51920.1 - 8.7 5.7 12.9 11 5.3 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) Asparaginase PF00710.20 CDJ51921.1 - 3.4e-12 46.3 0.0 3.4e-12 46.3 0.0 2.7 3 0 0 3 3 3 1 Asparaginase, N-terminal TFIIA PF03153.13 CDJ51921.1 - 0.0031 17.6 21.2 0.0031 17.6 21.2 2.6 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 CDJ51921.1 - 2.9 7.4 30.1 3.4 7.2 6.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4834 PF16118.5 CDJ51922.1 - 0.33 11.9 13.5 11 7.0 9.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ51922.1 - 0.4 9.4 13.7 0.8 8.4 3.4 2.1 2 0 0 2 2 2 0 Presenilin CCDC53 PF10152.9 CDJ51922.1 - 2 8.8 18.4 0.84 10.0 3.4 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Suf PF05843.14 CDJ51922.1 - 3.4 7.6 16.4 0.33 10.9 8.3 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PTPRCAP PF15713.5 CDJ51922.1 - 6.1 7.1 32.7 0.33 11.2 14.4 3.0 3 1 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated DUF1980 PF09323.10 CDJ51922.1 - 6.6 6.6 8.2 9.1 6.2 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) TMEM208_SND2 PF05620.11 CDJ51922.1 - 7.6 6.3 14.8 33 4.2 10.2 2.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Lyase_1 PF00206.20 CDJ51923.1 - 1.4e-29 103.5 0.0 1.5e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Lyase RhoGAP PF00620.27 CDJ51923.1 - 0.04 13.7 0.6 0.063 13.1 0.6 1.2 1 0 0 1 1 1 0 RhoGAP domain HD_3 PF13023.6 CDJ51924.1 - 1.1e-32 113.2 0.0 1.4e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CDJ51924.1 - 1.8e-12 47.4 0.0 2.2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CDJ51924.1 - 2.3e-06 27.8 0.1 8.7e-06 26.0 0.1 1.8 1 1 0 1 1 1 1 HD domain RD3 PF14473.6 CDJ51924.1 - 0.044 13.6 0.1 0.074 12.9 0.1 1.3 1 0 0 1 1 1 0 RD3 protein MORN PF02493.20 CDJ51925.1 - 6.1e-25 85.6 32.5 1.2e-06 28.0 1.2 5.7 6 0 0 6 6 6 5 MORN repeat TFIIA PF03153.13 CDJ51925.1 - 0.00096 19.3 37.5 0.0013 18.9 37.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Auxin_canalis PF05703.11 CDJ51925.1 - 0.003 17.5 25.0 0.0041 17.1 25.0 1.1 1 0 0 1 1 1 1 Auxin canalisation Macoilin PF09726.9 CDJ51925.1 - 0.0079 14.8 10.6 0.0082 14.8 10.6 1.1 1 0 0 1 1 1 1 Macoilin family CCSAP PF15748.5 CDJ51925.1 - 0.061 13.5 25.8 0.084 13.0 25.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated GAGA_bind PF06217.12 CDJ51925.1 - 0.14 12.4 19.2 0.2 11.9 19.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PNISR PF15996.5 CDJ51925.1 - 0.2 11.9 28.4 0.3 11.4 28.4 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Presenilin PF01080.17 CDJ51925.1 - 0.23 10.2 25.2 0.29 9.8 25.2 1.1 1 0 0 1 1 1 0 Presenilin DUF1387 PF07139.11 CDJ51925.1 - 0.34 10.6 20.9 0.46 10.2 20.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Hamartin PF04388.12 CDJ51925.1 - 0.39 9.3 16.5 0.45 9.1 16.5 1.1 1 0 0 1 1 1 0 Hamartin protein MMR1 PF08505.10 CDJ51925.1 - 0.63 10.3 23.7 0.86 9.8 23.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Tudor_2 PF18104.1 CDJ51925.1 - 1 9.1 0.0 1 9.1 0.0 3.0 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain DUF3807 PF12720.7 CDJ51925.1 - 1.2 9.3 27.3 2.2 8.5 27.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Draxin PF15550.6 CDJ51925.1 - 1.7 8.5 19.6 2.7 7.8 19.6 1.3 1 0 0 1 1 1 0 Draxin PAT1 PF09770.9 CDJ51925.1 - 1.7 6.8 30.2 2 6.6 30.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ51925.1 - 1.7 5.6 20.9 2 5.4 20.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer YfhO PF09586.10 CDJ51925.1 - 2.1 6.5 10.8 2.4 6.3 10.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO V_ATPase_I PF01496.19 CDJ51925.1 - 2.1 6.1 18.9 2.7 5.8 18.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 CDJ51925.1 - 2.3 8.0 24.8 3.4 7.4 24.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ51925.1 - 2.5 7.0 21.8 3.5 6.5 21.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NPR3 PF03666.13 CDJ51925.1 - 3 6.5 16.8 4.1 6.1 16.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Lin-8 PF03353.15 CDJ51925.1 - 4.5 6.7 27.8 2.8 7.4 26.3 1.3 2 0 0 2 2 1 0 Ras-mediated vulval-induction antagonist SKA1 PF07160.12 CDJ51925.1 - 4.7 7.0 22.4 6.4 6.5 22.4 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Golgin_A5 PF09787.9 CDJ51925.1 - 4.8 6.6 30.9 6.6 6.1 30.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Neur_chan_memb PF02932.16 CDJ51925.1 - 4.9 7.1 15.5 6.7 6.7 15.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.11 CDJ51925.1 - 7 6.6 19.1 9.4 6.2 19.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DOR PF14839.6 CDJ51925.1 - 8.7 6.2 22.1 14 5.6 22.1 1.4 1 0 0 1 1 1 0 DOR family Endostatin PF06482.11 CDJ51925.1 - 8.8 5.7 17.4 12 5.2 17.4 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Hid1 PF12722.7 CDJ51925.1 - 9.2 4.3 22.0 11 4.0 22.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 CDJ51925.1 - 9.4 4.9 18.3 12 4.6 18.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Pex14_N PF04695.13 CDJ51926.1 - 0.017 15.8 31.6 0.017 15.8 31.6 3.0 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ51927.1 - 0.19 11.3 11.9 0.24 11.0 11.9 1.1 1 0 0 1 1 1 0 Spt20 family Fcf1 PF04900.12 CDJ51928.1 - 2.9e-15 56.5 9.1 1.9e-08 34.6 0.0 4.1 3 1 0 3 3 3 2 Fcf1 Y_phosphatase3 PF13350.6 CDJ51928.1 - 0.001 19.1 1.3 0.001 19.1 1.3 3.3 3 2 0 3 3 3 1 Tyrosine phosphatase family RskA PF10099.9 CDJ51931.1 - 0.0057 17.0 18.0 0.0095 16.2 18.0 1.4 1 1 0 1 1 1 1 Anti-sigma-K factor rskA MCU PF04678.13 CDJ51931.1 - 0.29 11.2 7.2 0.32 11.1 7.2 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter VIR_N PF15912.5 CDJ51931.1 - 0.32 10.5 5.7 0.43 10.1 5.7 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal TMEM208_SND2 PF05620.11 CDJ51931.1 - 0.47 10.2 9.0 0.73 9.6 9.0 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DDHD PF02862.17 CDJ51931.1 - 0.67 10.1 6.9 0.66 10.1 6.9 1.1 1 0 0 1 1 1 0 DDHD domain Roughex PF06020.11 CDJ51931.1 - 0.72 8.9 8.0 0.7 8.9 8.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 CDJ51931.1 - 1.7 7.3 10.4 1.5 7.5 10.4 1.0 1 0 0 1 1 1 0 Presenilin Rxt3 PF08642.10 CDJ51931.1 - 1.9 9.3 6.1 2.3 9.0 6.1 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 EOS1 PF12326.8 CDJ51931.1 - 2.1 8.3 4.4 2.1 8.2 4.4 1.1 1 0 0 1 1 1 0 N-glycosylation protein R_equi_Vir PF05526.11 CDJ51931.1 - 2.6 7.9 6.0 3.3 7.5 6.0 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF4770 PF15994.5 CDJ51931.1 - 3.1 8.0 12.5 3.7 7.7 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Neur_chan_memb PF02932.16 CDJ51931.1 - 3.3 7.7 5.3 3.1 7.8 5.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ51931.1 - 3.5 7.4 13.8 3.6 7.3 13.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 CDJ51931.1 - 4 6.6 4.6 4.1 6.5 4.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 CDJ51931.1 - 4 6.2 4.1 3.7 6.4 4.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ctr PF04145.15 CDJ51931.1 - 4.4 7.9 4.5 4.9 7.8 4.5 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Coilin_N PF15862.5 CDJ51931.1 - 4.8 7.0 14.6 5.6 6.8 14.6 1.1 1 0 0 1 1 1 0 Coilin N-terminus Peptidase_S49_N PF08496.10 CDJ51931.1 - 5.6 7.0 11.6 6.4 6.8 11.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sedlin_N PF04628.13 CDJ51933.1 - 1.1e-12 48.2 0.0 1.5e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CDJ51933.1 - 0.0065 16.4 0.0 0.0066 16.4 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family BAF1_ABF1 PF04684.13 CDJ51941.1 - 0.15 11.1 7.8 0.17 10.9 7.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1645 PF07816.11 CDJ51941.1 - 0.19 12.3 23.2 1.5 9.4 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) RIFIN PF02009.16 CDJ51941.1 - 0.36 10.7 1.3 0.36 10.7 1.3 1.2 1 0 0 1 1 1 0 Rifin GREB1 PF15782.5 CDJ51941.1 - 0.58 7.2 11.0 0.61 7.1 11.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 CDJ51941.1 - 1.2 7.9 15.2 1.9 7.3 15.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pap_E4 PF02711.14 CDJ51941.1 - 2.4 9.2 7.7 1.4 9.9 1.2 2.2 2 0 0 2 2 2 0 E4 protein Myc_N PF01056.18 CDJ51941.1 - 4.9 7.0 18.0 6.5 6.6 18.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CytochromB561_N PF09786.9 CDJ51941.1 - 9.2 5.1 20.8 11 4.9 20.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Apt1 PF10351.9 CDJ51943.1 - 2.7 6.8 5.7 2.4 6.9 5.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF755 PF05501.11 CDJ51943.1 - 4.8 7.5 17.6 7 7.0 17.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) GvpH PF05455.11 CDJ51944.1 - 0.0025 17.9 0.0 0.0025 17.9 0.0 3.0 3 0 0 3 3 3 1 GvpH Ecl1 PF12855.7 CDJ51944.1 - 0.024 15.8 13.8 0.024 15.8 13.8 3.8 2 1 1 3 3 3 0 ECL1/2/3 zinc binding proteins JUPITER PF17054.5 CDJ51945.1 - 0.0025 17.3 0.2 0.0052 16.3 0.2 1.4 1 0 0 1 1 1 1 Microtubule-Associated protein Jupiter Glt_symporter PF03616.14 CDJ51945.1 - 0.23 10.1 0.7 0.44 9.2 0.7 1.4 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF2975 PF11188.8 CDJ51945.1 - 0.82 9.6 4.2 0.73 9.7 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) ODV-E18 PF10717.9 CDJ51946.1 - 0.048 13.5 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 RskA PF10099.9 CDJ51946.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ51946.1 - 0.34 9.6 11.2 0.41 9.4 11.2 1.2 1 0 0 1 1 1 0 Presenilin GN3L_Grn1 PF08701.11 CDJ51946.1 - 0.43 10.7 18.0 0.91 9.7 5.0 2.2 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase Gp_dh_C PF02800.20 CDJ51948.1 - 1.7e-60 203.2 0.0 4.8e-60 201.7 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain MIF4G PF02854.19 CDJ51948.1 - 2.1e-18 66.8 0.2 4.8e-18 65.6 0.2 1.7 1 0 0 1 1 1 1 MIF4G domain Spt20 PF12090.8 CDJ51949.1 - 0.0028 17.3 30.8 0.013 15.1 2.1 2.2 2 0 0 2 2 2 2 Spt20 family UPF0697 PF15117.6 CDJ51949.1 - 0.0081 16.2 0.6 0.0081 16.2 0.6 2.6 2 1 0 2 2 1 1 Uncharacterised protein family UPF0697 Piezo_RRas_bdg PF12166.8 CDJ51949.1 - 0.023 14.0 7.7 0.029 13.7 7.7 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Presenilin PF01080.17 CDJ51949.1 - 0.048 12.4 8.9 0.063 12.0 8.9 1.3 1 0 0 1 1 1 0 Presenilin Rft-1 PF04506.13 CDJ51949.1 - 0.079 11.7 3.1 0.094 11.4 3.1 1.1 1 0 0 1 1 1 0 Rft protein DUF4231 PF14015.6 CDJ51949.1 - 0.15 12.5 12.0 0.06 13.8 2.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Activator_LAG-3 PF11498.8 CDJ51949.1 - 0.4 9.6 41.6 0.94 8.4 5.5 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Tau95_N PF17682.1 CDJ51949.1 - 0.64 10.2 7.1 1.3 9.2 2.8 2.2 2 0 0 2 2 2 0 Tau95 Triple barrel domain FAM176 PF14851.6 CDJ51949.1 - 0.67 9.6 5.9 0.6 9.8 1.3 2.1 2 0 0 2 2 2 0 FAM176 family DUF4825 PF16107.5 CDJ51949.1 - 0.74 10.0 4.8 3.9 7.7 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4825) SOBP PF15279.6 CDJ51949.1 - 0.75 10.3 11.8 0.98 10.0 11.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S64 PF08192.11 CDJ51949.1 - 0.97 7.8 12.4 1.1 7.7 12.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 SLC12 PF03522.15 CDJ51949.1 - 1.3 7.9 9.0 1.8 7.5 9.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 PPL5 PF18168.1 CDJ51949.1 - 1.6 7.9 10.5 3.2 7.0 5.6 2.1 2 0 0 2 2 2 0 Prim-pol family 5 MPM1 PF17234.2 CDJ51949.1 - 2.3 8.4 11.4 2.1 8.6 4.9 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Coiled-coil_56 PF09813.9 CDJ51949.1 - 2.4 8.3 12.4 0.2 11.7 3.0 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 56 DUF4834 PF16118.5 CDJ51949.1 - 2.8 8.9 14.6 3.9 8.5 7.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Ndc1_Nup PF09531.10 CDJ51949.1 - 3.1 6.4 16.0 3.8 6.1 16.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNA_pol_Rbc25 PF08292.12 CDJ51949.1 - 5.4 7.3 10.3 1.2 9.3 3.5 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 EIIBC-GUT_N PF03612.14 CDJ51949.1 - 5.9 6.6 13.9 0.47 10.2 4.9 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Rsc14 PF08586.10 CDJ51949.1 - 7 7.5 8.5 33 5.4 0.3 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DUF4207 PF13904.6 CDJ51949.1 - 8.5 6.0 26.7 3.8 7.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Rxt3 PF08642.10 CDJ51949.1 - 9.9 7.0 7.2 13 6.6 3.5 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF1115 PF06544.12 CDJ51950.1 - 7.1e-20 71.6 0.1 8.5e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Spt20 PF12090.8 CDJ51951.1 - 0.00029 20.5 10.7 0.00029 20.5 10.7 7.3 6 1 0 6 6 6 3 Spt20 family SR-25 PF10500.9 CDJ51951.1 - 0.00064 19.4 14.6 0.00064 19.4 14.6 15.0 13 2 3 16 16 16 6 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ51951.1 - 0.00069 19.9 3.8 0.00069 19.9 3.8 17.0 16 2 1 17 17 17 1 Domain of unknown function (DUF755) DUF2722 PF10846.8 CDJ51951.1 - 0.0027 16.7 13.4 0.0027 16.7 13.4 7.8 7 1 0 7 7 7 2 Protein of unknown function (DUF2722) MecA PF05389.12 CDJ51951.1 - 4 7.0 13.7 2.5 7.7 0.7 3.3 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) FAM176 PF14851.6 CDJ51952.1 - 0.026 14.2 4.0 0.03 14.0 4.0 1.1 1 0 0 1 1 1 0 FAM176 family Spt20 PF12090.8 CDJ51952.1 - 0.034 13.8 23.9 0.039 13.6 23.9 1.1 1 0 0 1 1 1 0 Spt20 family RED_N PF07808.13 CDJ51952.1 - 0.068 12.7 8.6 0.073 12.6 8.6 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region MAP65_ASE1 PF03999.12 CDJ51952.1 - 0.073 11.8 12.7 0.083 11.6 12.7 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) HGTP_anticodon2 PF12745.7 CDJ51952.1 - 0.23 10.9 7.6 0.26 10.7 7.6 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs PigN PF04987.14 CDJ51952.1 - 0.32 9.8 3.0 0.34 9.7 3.0 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF2722 PF10846.8 CDJ51952.1 - 0.36 9.7 22.1 0.41 9.5 22.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ51952.1 - 0.38 11.4 16.0 0.43 11.2 16.0 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PTPRCAP PF15713.5 CDJ51952.1 - 0.49 10.7 9.8 0.58 10.4 9.8 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CobT PF06213.12 CDJ51952.1 - 0.5 9.7 11.7 0.5 9.7 11.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ALMT PF11744.8 CDJ51952.1 - 0.5 9.1 5.1 0.54 9.0 5.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 CDJ51952.1 - 0.51 10.3 23.4 0.57 10.1 23.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EIIBC-GUT_N PF03612.14 CDJ51952.1 - 0.61 9.8 5.7 0.61 9.8 5.7 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SUFU_C PF12470.8 CDJ51952.1 - 0.67 10.0 6.3 0.74 9.8 6.3 1.0 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain DDHD PF02862.17 CDJ51952.1 - 0.83 9.8 6.1 0.87 9.7 6.1 1.1 1 0 0 1 1 1 0 DDHD domain RBP_receptor PF14752.6 CDJ51952.1 - 1.4 7.4 5.8 1.4 7.4 5.8 1.0 1 0 0 1 1 1 0 Retinol binding protein receptor Sec62 PF03839.16 CDJ51952.1 - 1.5 8.3 6.7 1.7 8.1 6.7 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 TERB2 PF15101.6 CDJ51952.1 - 1.9 8.5 12.8 2 8.4 12.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4770 PF15994.5 CDJ51952.1 - 1.9 8.7 10.5 2.2 8.5 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Connexin PF00029.19 CDJ51952.1 - 2 8.1 5.6 2.1 8.0 5.6 1.2 1 0 0 1 1 1 0 Connexin UPF0560 PF10577.9 CDJ51952.1 - 2 6.8 12.2 2.1 6.7 12.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CLN3 PF02487.17 CDJ51952.1 - 2.5 7.0 4.9 2.6 7.0 4.9 1.0 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 CDJ51952.1 - 2.7 8.0 7.2 3 7.8 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 CDJ51952.1 - 3 5.6 7.5 3 5.7 7.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.7 CDJ51952.1 - 3.1 5.8 7.7 3.4 5.7 7.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OATP PF03137.20 CDJ51952.1 - 4 5.6 4.4 3.9 5.7 4.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ctr PF04145.15 CDJ51952.1 - 4.4 7.9 5.2 5.1 7.7 5.2 1.1 1 0 0 1 1 1 0 Ctr copper transporter family MAJIN PF15077.6 CDJ51952.1 - 4.5 7.0 8.1 5.2 6.8 8.1 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Folate_carrier PF01770.18 CDJ51952.1 - 4.6 5.9 4.5 5.2 5.7 4.5 1.0 1 0 0 1 1 1 0 Reduced folate carrier Presenilin PF01080.17 CDJ51952.1 - 4.8 5.8 12.5 5.4 5.7 12.5 1.0 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CDJ51952.1 - 5.6 6.2 11.3 6.4 6.0 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SID-1_RNA_chan PF13965.6 CDJ51952.1 - 6 5.1 5.3 6.8 5.0 5.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF-3_zeta PF05091.12 CDJ51952.1 - 6.2 5.7 13.9 6.5 5.6 13.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PepSY_TM PF03929.16 CDJ51952.1 - 6.4 6.4 4.7 6.5 6.3 4.7 1.0 1 0 0 1 1 1 0 PepSY-associated TM region Suf PF05843.14 CDJ51952.1 - 9 6.2 13.4 9.9 6.0 13.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GST_C_3 PF14497.6 CDJ51953.1 - 2.4e-05 24.4 0.0 7.6e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDJ51953.1 - 0.0088 16.2 0.0 0.0088 16.2 0.0 2.6 2 1 0 2 2 1 1 Glutathione S-transferase, C-terminal domain BAF1_ABF1 PF04684.13 CDJ51953.1 - 0.014 14.5 15.1 0.017 14.2 15.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GST_C_2 PF13410.6 CDJ51953.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Borrelia_P83 PF05262.11 CDJ51953.1 - 0.99 7.8 22.9 1.2 7.5 22.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CCSAP PF15748.5 CDJ51953.1 - 1.6 8.8 23.9 2.3 8.3 23.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Ndc1_Nup PF09531.10 CDJ51953.1 - 2.2 6.9 22.0 2.8 6.5 22.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 CDJ51953.1 - 2.8 6.1 33.2 3.5 5.8 33.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ51953.1 - 3.5 4.6 16.9 4.1 4.4 16.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 CDJ51953.1 - 3.9 6.0 15.1 4.8 5.7 15.1 1.1 1 0 0 1 1 1 0 Hamartin protein SRP-alpha_N PF04086.13 CDJ51953.1 - 5.9 6.7 24.1 8.1 6.3 24.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Med15 PF09606.10 CDJ51953.1 - 6.9 5.2 48.1 8.6 4.9 48.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 CDJ51953.1 - 9.2 4.9 25.4 14 4.3 25.4 1.2 1 0 0 1 1 1 0 Presenilin MRP-S31 PF15433.6 CDJ51954.1 - 9.7 5.8 14.1 13 5.3 14.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PAP2 PF01569.21 CDJ51955.1 - 0.0018 18.0 2.5 0.7 9.7 4.2 2.8 2 1 0 2 2 2 1 PAP2 superfamily SLATT_5 PF18160.1 CDJ51955.1 - 0.28 10.5 1.1 0.65 9.3 1.1 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Prominin PF05478.11 CDJ51955.1 - 1.5 6.6 10.4 2.8 5.8 10.4 1.4 1 0 0 1 1 1 0 Prominin DUF2339 PF10101.9 CDJ51955.1 - 2.7 6.5 26.7 0.31 9.6 17.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) ABC2_membrane_3 PF12698.7 CDJ51955.1 - 7.2 5.6 6.6 7.9 5.5 2.5 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein CcmF_C PF16327.5 CDJ51955.1 - 8.8 5.5 13.3 4.9 6.4 9.1 2.2 2 0 0 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal MBR1 PF17058.5 CDJ51956.1 - 0.021 15.1 13.4 0.032 14.5 13.4 1.2 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 LMBR1 PF04791.16 CDJ51956.1 - 3.4 6.5 8.9 3.4 6.5 8.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 CDJ51956.1 - 4.2 6.0 30.7 5.8 5.6 30.7 1.2 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 CDJ51957.1 - 0.027 14.8 55.2 0.075 13.3 0.0 6.6 3 2 2 5 5 5 0 Anti-sigma-K factor rskA DDHD PF02862.17 CDJ51957.1 - 0.086 13.0 0.1 0.086 13.0 0.1 5.9 3 2 1 4 4 4 0 DDHD domain RR_TM4-6 PF06459.12 CDJ51958.1 - 0.0022 17.9 26.9 0.0026 17.6 26.9 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 AF-4 PF05110.13 CDJ51958.1 - 0.0074 14.4 36.4 0.0095 14.1 36.4 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Endostatin PF06482.11 CDJ51958.1 - 0.009 15.5 21.6 0.012 15.1 21.6 1.3 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin CNDH2_C PF16858.5 CDJ51958.1 - 0.026 14.4 24.8 0.033 14.1 24.8 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF572 PF04502.13 CDJ51958.1 - 0.048 13.3 25.0 0.06 13.0 25.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hamartin PF04388.12 CDJ51958.1 - 0.12 11.0 27.5 0.15 10.7 27.5 1.0 1 0 0 1 1 1 0 Hamartin protein Dicty_REP PF05086.12 CDJ51958.1 - 0.14 10.1 23.1 0.17 9.8 23.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CCSAP PF15748.5 CDJ51958.1 - 0.15 12.2 37.6 0.2 11.8 37.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated BAF1_ABF1 PF04684.13 CDJ51958.1 - 0.2 10.7 27.1 0.27 10.2 27.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Hid1 PF12722.7 CDJ51958.1 - 0.21 9.7 28.5 0.26 9.4 28.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop53 PF07767.11 CDJ51958.1 - 0.21 10.9 36.0 0.29 10.5 36.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF966 PF06136.13 CDJ51958.1 - 0.23 11.1 22.2 0.27 10.9 22.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) XRN_M PF17846.1 CDJ51958.1 - 0.23 10.3 20.5 0.3 10.0 20.5 1.2 1 0 0 1 1 1 0 Xrn1 helical domain stn_TNFRSF12A PF12191.8 CDJ51958.1 - 0.24 11.6 1.2 0.69 10.1 0.0 2.1 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Raftlin PF15250.6 CDJ51958.1 - 0.28 9.9 25.9 0.35 9.6 25.9 1.1 1 0 0 1 1 1 0 Raftlin Exonuc_VII_L PF02601.15 CDJ51958.1 - 0.34 10.4 31.9 0.44 10.1 31.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1387 PF07139.11 CDJ51958.1 - 0.43 10.3 29.6 0.55 9.9 29.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) O-antigen_lig PF13425.6 CDJ51958.1 - 0.77 8.5 15.1 0.95 8.2 15.1 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SWI-SNF_Ssr4 PF08549.10 CDJ51958.1 - 0.84 8.2 30.2 1.2 7.7 30.2 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SOBP PF15279.6 CDJ51958.1 - 0.84 10.2 31.1 1.1 9.8 31.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PPP4R2 PF09184.11 CDJ51958.1 - 0.92 9.0 22.2 1.2 8.7 22.2 1.1 1 0 0 1 1 1 0 PPP4R2 LAP1C PF05609.12 CDJ51958.1 - 0.97 8.5 32.9 1.2 8.1 32.9 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2052 PF09747.9 CDJ51958.1 - 1.3 9.1 31.7 1.9 8.6 31.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Draxin PF15550.6 CDJ51958.1 - 1.4 8.7 23.2 2.1 8.1 23.2 1.3 1 0 0 1 1 1 0 Draxin DUF4045 PF13254.6 CDJ51958.1 - 2.2 7.8 29.6 2.9 7.4 29.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) UPF0564 PF10595.9 CDJ51958.1 - 2.4 7.1 46.5 3.6 6.6 46.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 SLC12 PF03522.15 CDJ51958.1 - 5 6.0 33.6 7.2 5.5 33.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DDRGK PF09756.9 CDJ51958.1 - 5 6.7 36.5 9.2 5.8 36.5 1.5 1 0 0 1 1 1 0 DDRGK domain IHABP4_N PF16174.5 CDJ51958.1 - 6.6 7.3 39.3 12 6.5 39.3 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4407 PF14362.6 CDJ51959.1 - 4.3 6.6 28.6 5 6.4 28.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4551 PF15087.6 CDJ51959.1 - 5.8 5.6 36.6 6.8 5.4 36.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) AUX_IAA PF02309.16 CDJ51959.1 - 6.7 6.5 23.6 8.4 6.2 23.6 1.2 1 0 0 1 1 1 0 AUX/IAA family WD40 PF00400.32 CDJ51960.1 - 4.6e-19 68.4 6.3 0.0011 19.7 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ51960.1 - 2.6e-05 24.4 0.7 0.06 13.7 0.1 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ51960.1 - 0.046 12.4 0.3 4.4 5.8 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF5540 PF17694.1 CDJ51960.1 - 0.12 12.9 0.1 0.29 11.7 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5540) Ribosomal_L5e PF17144.4 CDJ51961.1 - 2e-59 200.2 5.0 1.7e-37 128.9 4.2 2.6 2 1 1 3 3 3 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CDJ51961.1 - 1.9e-30 105.7 6.2 1.9e-30 105.7 6.2 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region RCC1 PF00415.18 CDJ51962.1 - 5.7e-47 158.1 29.4 6.9e-11 42.6 1.9 8.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ51962.1 - 1.8e-28 97.7 53.5 7.9e-09 35.1 0.9 7.0 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 CDJ51962.1 - 3.4e-05 23.7 3.2 2.3 7.9 0.0 4.9 5 0 0 5 5 5 2 TUP1-like enhancer of split Apt1 PF10351.9 CDJ51962.1 - 0.004 16.1 2.2 0.004 16.1 2.2 1.5 2 0 0 2 2 2 1 Golgi-body localisation protein domain DUF2722 PF10846.8 CDJ51962.1 - 0.022 13.7 0.1 0.022 13.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Roughex PF06020.11 CDJ51962.1 - 0.67 9.0 5.2 1.2 8.2 5.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ51962.1 - 1.3 8.6 10.8 2.5 7.6 10.8 1.4 1 0 0 1 1 1 0 Spt20 family Thioredoxin PF00085.20 CDJ51963.1 - 5.6e-14 52.0 0.0 1.2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CDJ51963.1 - 1.5e-07 31.5 0.0 2.7e-05 24.1 0.0 3.3 4 0 0 4 4 4 1 Thioredoxin-like domain SR-25 PF10500.9 CDJ51963.1 - 0.06 13.0 42.2 0.092 12.3 1.6 3.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ51963.1 - 1.3 9.2 13.8 11 6.1 0.4 3.3 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated Secretin_N_2 PF07655.13 CDJ51963.1 - 2.4 8.8 27.0 20 5.8 0.1 3.4 3 0 0 3 3 3 0 Secretin N-terminal domain DUF3446 PF11928.8 CDJ51963.1 - 4.7 7.6 47.2 0.69 10.3 8.7 5.0 4 1 1 5 5 5 0 Early growth response N-terminal domain DUF2722 PF10846.8 CDJ51964.1 - 1.2e-05 24.4 1.1 1.2e-05 24.4 1.1 7.8 4 3 3 7 7 7 1 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ51964.1 - 4.9e-05 23.0 20.8 4.9e-05 23.0 20.8 6.1 5 2 1 6 6 6 3 Nuclear RNA-splicing-associated protein ubiquitin PF00240.23 CDJ51966.1 - 1.1e-05 25.1 0.0 3.1e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ51966.1 - 0.00049 19.9 0.0 0.0021 17.8 0.0 2.1 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like HemX PF04375.14 CDJ51966.1 - 0.0026 17.1 1.6 0.0026 17.1 1.6 1.8 2 0 0 2 2 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase SUIM_assoc PF16619.5 CDJ51966.1 - 0.026 14.6 0.6 0.026 14.6 0.6 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3854 PF12965.7 CDJ51966.1 - 0.077 13.0 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Spt20 PF12090.8 CDJ51966.1 - 1.3 8.6 15.6 0.91 9.1 7.4 2.1 2 0 0 2 2 2 0 Spt20 family eIF-3_zeta PF05091.12 CDJ51967.1 - 0.27 10.2 16.6 0.31 10.0 16.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_23 PF13476.6 CDJ51967.1 - 0.28 11.6 15.6 0.45 11.0 15.6 1.3 1 0 0 1 1 1 0 AAA domain Myco_haema PF05692.12 CDJ51967.1 - 1.3 7.9 14.9 0.04 12.9 7.7 2.0 2 0 0 2 2 2 0 Mycoplasma haemagglutinin Serinc PF03348.15 CDJ51967.1 - 6 5.7 9.1 11 4.8 9.1 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Esterase PF00756.20 CDJ51967.1 - 6.3 6.4 13.9 0.084 12.5 6.4 1.7 2 0 0 2 2 2 0 Putative esterase Prominin PF05478.11 CDJ51969.1 - 0.0036 15.4 0.3 0.0041 15.2 0.3 1.1 1 0 0 1 1 1 1 Prominin DUF573 PF04504.14 CDJ51969.1 - 0.045 14.4 0.1 20 5.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function, DUF573 N2227 PF07942.12 CDJ51969.1 - 0.045 12.9 0.1 0.094 11.9 0.0 1.5 2 0 0 2 2 2 0 N2227-like protein Apolipoprotein PF01442.18 CDJ51969.1 - 0.071 13.0 0.0 0.33 10.8 0.0 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 CDJ51969.1 - 0.081 13.1 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMEM82 PF15816.5 CDJ51970.1 - 0.034 13.1 0.0 0.077 12.0 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 82 Ribosomal_S13 PF00416.22 CDJ51972.1 - 4.8e-51 172.5 0.9 5.7e-51 172.2 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CDJ51972.1 - 0.0075 15.1 0.0 0.0075 15.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Piezo_RRas_bdg PF12166.8 CDJ51973.1 - 0.45 9.7 3.3 0.41 9.9 3.3 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain TFIIA PF03153.13 CDJ51973.1 - 0.97 9.4 30.6 1.3 9.0 30.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit JAB PF01398.21 CDJ51974.1 - 2.2e-11 43.8 0.0 2.9e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease eIF3_p135 PF12807.7 CDJ51975.1 - 0.0057 16.7 2.3 0.0074 16.3 2.3 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 Mlh1_C PF16413.5 CDJ51975.1 - 0.018 14.4 6.3 0.023 14.1 6.3 1.1 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus TFIIA PF03153.13 CDJ51975.1 - 0.045 13.7 37.3 0.054 13.5 37.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OATP PF03137.20 CDJ51975.1 - 0.23 9.7 2.6 0.3 9.3 2.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family INSIG PF07281.12 CDJ51975.1 - 0.32 10.6 5.6 0.25 10.9 4.7 1.5 1 1 0 1 1 1 0 Insulin-induced protein (INSIG) Exonuc_VII_L PF02601.15 CDJ51975.1 - 0.4 10.2 18.7 0.49 9.9 18.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FragX_IP PF05994.11 CDJ51975.1 - 0.42 8.6 7.4 0.48 8.4 7.4 1.0 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family DUF4342 PF14242.6 CDJ51975.1 - 0.43 10.6 0.0 0.43 10.6 0.0 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4342) FAM60A PF15396.6 CDJ51975.1 - 0.52 10.3 5.8 0.63 10.0 5.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF572 PF04502.13 CDJ51975.1 - 0.53 9.9 9.1 0.58 9.7 9.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RAB3GAP2_N PF14655.6 CDJ51975.1 - 0.57 9.4 8.1 0.7 9.1 8.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DDHD PF02862.17 CDJ51975.1 - 0.88 9.7 7.3 0.99 9.5 7.3 1.2 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 CDJ51975.1 - 0.88 7.4 7.4 0.94 7.3 7.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAT1 PF06391.13 CDJ51975.1 - 1.5 8.6 14.0 2.1 8.2 14.0 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 GET2 PF08690.10 CDJ51975.1 - 1.6 8.4 14.9 2 8.0 14.9 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 RR_TM4-6 PF06459.12 CDJ51975.1 - 1.8 8.3 10.0 2.1 8.1 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hydin_ADK PF17213.3 CDJ51975.1 - 1.9 8.8 14.9 2.5 8.4 14.9 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Neur_chan_memb PF02932.16 CDJ51975.1 - 1.9 8.5 7.4 2.2 8.3 7.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RIFIN PF02009.16 CDJ51975.1 - 2.5 7.9 18.4 2.8 7.8 18.4 1.0 1 0 0 1 1 1 0 Rifin Presenilin PF01080.17 CDJ51975.1 - 3.1 6.5 11.0 3.4 6.3 11.0 1.1 1 0 0 1 1 1 0 Presenilin DUF2232 PF09991.9 CDJ51975.1 - 3.5 6.7 11.1 6.1 5.9 0.5 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) Activator_LAG-3 PF11498.8 CDJ51975.1 - 3.5 6.5 39.7 4.4 6.2 39.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF2347 PF09804.9 CDJ51975.1 - 6.5 6.3 6.6 8.1 5.9 6.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) SKA1 PF07160.12 CDJ51975.1 - 7.8 6.3 13.9 9.8 6.0 13.9 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 SUIM_assoc PF16619.5 CDJ51976.1 - 0.0076 16.3 6.6 0.0076 16.3 6.6 11.9 9 4 2 11 11 11 2 Unstructured region C-term to UIM in Ataxin3 Lin-8 PF03353.15 CDJ51977.1 - 0.0083 15.7 23.4 0.012 15.2 23.4 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 CDJ51977.1 - 0.015 13.6 33.6 0.02 13.2 33.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ51977.1 - 0.018 13.3 19.5 0.023 13.0 19.5 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 CDJ51977.1 - 0.03 13.1 19.7 0.039 12.8 19.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Otopetrin PF03189.13 CDJ51977.1 - 0.041 12.7 4.9 0.04 12.7 4.9 1.2 1 0 0 1 1 1 0 Otopetrin Tim54 PF11711.8 CDJ51977.1 - 0.052 12.3 19.1 0.092 11.5 19.1 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PIP5K PF01504.18 CDJ51977.1 - 0.057 12.6 15.0 0.095 11.9 15.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Apt1 PF10351.9 CDJ51977.1 - 0.058 12.3 14.2 0.072 11.9 14.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dicty_REP PF05086.12 CDJ51977.1 - 0.075 11.0 11.3 0.083 10.9 11.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S64 PF08192.11 CDJ51977.1 - 0.09 11.3 18.2 0.1 11.1 18.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 MAJIN PF15077.6 CDJ51977.1 - 0.093 12.5 13.9 0.15 11.8 13.9 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Hid1 PF12722.7 CDJ51977.1 - 0.11 10.6 18.7 0.13 10.4 18.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 CDJ51977.1 - 0.16 11.0 22.1 0.21 10.6 22.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 NARP1 PF12569.8 CDJ51977.1 - 0.17 10.8 19.4 0.29 10.0 19.4 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cellulose_synt PF03552.14 CDJ51977.1 - 0.2 10.1 5.3 0.22 10.0 5.3 1.1 1 0 0 1 1 1 0 Cellulose synthase GREB1 PF15782.5 CDJ51977.1 - 0.22 8.6 20.1 0.27 8.3 20.1 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAPS PF04499.15 CDJ51977.1 - 0.25 10.1 15.9 0.33 9.7 15.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pkinase_fungal PF17667.1 CDJ51977.1 - 0.34 9.6 8.8 0.41 9.4 8.8 1.2 1 0 0 1 1 1 0 Fungal protein kinase Endostatin PF06482.11 CDJ51977.1 - 0.35 10.3 19.1 0.59 9.5 19.1 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CCSAP PF15748.5 CDJ51977.1 - 0.39 10.8 32.6 0.52 10.4 26.4 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated O-antigen_lig PF13425.6 CDJ51977.1 - 0.4 9.4 8.5 0.47 9.2 8.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF913 PF06025.12 CDJ51977.1 - 0.5 9.3 17.0 0.065 12.2 13.0 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF2828 PF11443.8 CDJ51977.1 - 0.52 8.3 22.2 0.75 7.8 22.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) AAA_11 PF13086.6 CDJ51977.1 - 0.57 9.9 21.1 0.95 9.2 21.1 1.3 1 0 0 1 1 1 0 AAA domain Pox_Ag35 PF03286.14 CDJ51977.1 - 0.57 9.9 16.5 1 9.1 16.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.12 CDJ51977.1 - 0.61 9.9 30.8 0.04 13.8 25.3 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 YABBY PF04690.13 CDJ51977.1 - 0.7 10.5 14.3 1.2 9.7 14.3 1.5 1 0 0 1 1 1 0 YABBY protein MDM10 PF12519.8 CDJ51977.1 - 0.71 8.7 17.7 0.95 8.3 17.7 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4776 PF16003.5 CDJ51977.1 - 0.74 8.7 19.7 1 8.3 19.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) TRAP_alpha PF03896.16 CDJ51977.1 - 0.89 8.7 12.4 1.8 7.7 12.4 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PA26 PF04636.13 CDJ51977.1 - 1.3 7.9 16.0 1.7 7.5 16.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TT_ORF1 PF02956.14 CDJ51977.1 - 1.4 7.5 15.9 1.7 7.2 15.9 1.1 1 0 0 1 1 1 0 TT viral orf 1 ALMT PF11744.8 CDJ51977.1 - 1.4 7.7 18.2 2.1 7.1 18.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM60A PF15396.6 CDJ51977.1 - 1.8 8.5 23.4 0.091 12.8 17.9 1.6 2 0 0 2 2 1 0 Protein Family FAM60A Sin_N PF04801.13 CDJ51977.1 - 1.9 7.6 32.9 3 6.9 32.9 1.4 1 0 0 1 1 1 0 Sin-like protein conserved region Membralin PF09746.9 CDJ51977.1 - 2.5 7.1 14.7 3.2 6.7 14.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein SART-1 PF03343.13 CDJ51977.1 - 3.1 6.2 33.9 0.092 11.3 27.9 1.4 2 0 0 2 2 2 0 SART-1 family RPN2_C PF18004.1 CDJ51977.1 - 3.2 7.6 24.5 0.42 10.5 20.1 1.8 2 0 0 2 2 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2151 PF10221.9 CDJ51977.1 - 3.4 6.1 15.8 4.4 5.8 15.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4746 PF15928.5 CDJ51977.1 - 4.2 6.7 22.6 6.9 6.0 22.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MCM_bind PF09739.9 CDJ51977.1 - 5 5.4 25.4 7.9 4.8 25.4 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Bul1_N PF04425.12 CDJ51977.1 - 5.1 5.7 19.8 7.3 5.2 19.8 1.1 1 0 0 1 1 1 0 Bul1 N terminus Exonuc_VII_L PF02601.15 CDJ51977.1 - 5.1 6.6 23.8 8 5.9 23.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SID-1_RNA_chan PF13965.6 CDJ51977.1 - 5.4 5.3 12.8 7 4.9 12.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Asp-B-Hydro_N PF05279.11 CDJ51977.1 - 5.4 7.0 22.7 0.45 10.5 18.1 1.5 2 0 0 2 2 1 0 Aspartyl beta-hydroxylase N-terminal region VIR_N PF15912.5 CDJ51977.1 - 6.6 6.2 17.4 9.8 5.7 17.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal TCP PF03634.13 CDJ51977.1 - 6.9 7.2 32.5 17 6.0 0.5 2.2 2 0 0 2 2 2 0 TCP family transcription factor Serinc PF03348.15 CDJ51977.1 - 7.3 5.4 18.4 14 4.5 18.4 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Borrelia_P83 PF05262.11 CDJ51977.1 - 8.7 4.7 30.5 12 4.2 30.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein TMPIT PF07851.13 CDJ51977.1 - 10 5.3 18.0 13 5.0 18.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein zf-rbx1 PF12678.7 CDJ51978.1 - 1.1e-05 25.6 3.0 2.3e-05 24.6 3.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CDJ51978.1 - 4.1e-05 23.6 2.1 5.9e-05 23.0 2.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SR-25 PF10500.9 CDJ51978.1 - 0.0071 16.0 21.1 0.0081 15.8 21.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ51978.1 - 0.2 10.4 3.7 0.2 10.5 3.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pox_A12 PF04651.13 CDJ51978.1 - 0.36 10.9 6.4 0.4 10.7 6.4 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein Macoilin PF09726.9 CDJ51978.1 - 0.46 9.0 4.3 0.43 9.1 4.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF1645 PF07816.11 CDJ51978.1 - 0.49 11.0 10.4 0.62 10.6 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) SSP160 PF06933.11 CDJ51978.1 - 0.67 8.1 19.9 0.69 8.0 19.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF508 PF04370.12 CDJ51978.1 - 1.3 8.8 11.1 1.8 8.3 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) TraG-D_C PF12696.7 CDJ51978.1 - 1.8 8.6 8.6 0.3 11.1 5.2 1.5 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG DUF4680 PF15730.5 CDJ51978.1 - 1.8 8.9 8.4 2.3 8.6 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) CCDC106 PF15794.5 CDJ51978.1 - 3.5 7.3 7.4 4.2 7.0 7.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4692 PF15763.5 CDJ51978.1 - 7.2 7.0 12.5 9.2 6.7 12.5 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) FSA_C PF10479.9 CDJ51978.1 - 8.3 4.4 11.4 9 4.3 11.4 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RskA PF10099.9 CDJ51979.1 - 0.014 15.7 16.6 0.016 15.5 16.6 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Trp_oprn_chp PF09534.10 CDJ51979.1 - 0.12 12.2 5.4 0.14 12.0 5.4 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FHIPEP PF00771.20 CDJ51979.1 - 0.26 9.7 10.0 0.25 9.8 10.0 1.0 1 0 0 1 1 1 0 FHIPEP family CD20 PF04103.15 CDJ51979.1 - 0.36 10.9 0.5 0.35 10.9 0.5 1.0 1 0 0 1 1 1 0 CD20-like family HA2 PF04408.23 CDJ51979.1 - 0.38 11.1 7.4 0.4 11.0 7.4 1.0 1 0 0 1 1 1 0 Helicase associated domain (HA2) CbiD PF01888.17 CDJ51979.1 - 0.4 9.9 5.7 0.42 9.9 5.7 1.0 1 0 0 1 1 1 0 CbiD PepSY_2 PF13670.6 CDJ51979.1 - 0.43 10.6 12.4 0.6 10.1 12.4 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain EphA2_TM PF14575.6 CDJ51979.1 - 0.58 11.1 4.5 0.72 10.8 4.5 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 CDJ51979.1 - 0.65 11.0 13.4 0.69 10.9 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SpoIIP PF07454.11 CDJ51979.1 - 0.74 9.2 12.2 0.72 9.3 12.2 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4820 PF16091.5 CDJ51979.1 - 0.84 8.9 10.2 0.86 8.9 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) THOC2_N PF16134.5 CDJ51979.1 - 1.2 7.6 12.0 1.3 7.5 12.0 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Connexin PF00029.19 CDJ51979.1 - 1.3 8.7 8.9 1.3 8.8 8.9 1.0 1 0 0 1 1 1 0 Connexin O-antigen_lig PF13425.6 CDJ51979.1 - 1.7 7.4 2.5 1.6 7.5 2.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Coilin_N PF15862.5 CDJ51979.1 - 2 8.2 15.7 2.1 8.2 15.7 1.0 1 0 0 1 1 1 0 Coilin N-terminus AIF_C PF14721.6 CDJ51979.1 - 2.1 8.7 11.4 2.2 8.6 11.4 1.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ureide_permease PF07168.11 CDJ51979.1 - 2.1 7.0 5.6 2.2 7.0 5.6 1.0 1 0 0 1 1 1 0 Ureide permease OATP PF03137.20 CDJ51979.1 - 2.5 6.3 6.6 2.3 6.4 6.6 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DcuA_DcuB PF03605.14 CDJ51979.1 - 2.6 6.9 4.6 2.8 6.8 4.6 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Presenilin PF01080.17 CDJ51979.1 - 2.9 6.6 14.0 2.9 6.6 14.0 1.0 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ51979.1 - 2.9 5.7 11.6 2.6 5.9 11.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1980 PF09323.10 CDJ51979.1 - 3.9 7.4 8.5 3.7 7.4 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3464 PF11947.8 CDJ51979.1 - 3.9 7.2 11.9 3.8 7.2 11.9 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TMEM208_SND2 PF05620.11 CDJ51979.1 - 4 7.2 10.8 4.5 7.0 10.8 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 CTU2 PF10288.9 CDJ51979.1 - 4.4 7.6 12.8 4.5 7.5 12.8 1.0 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 PigN PF04987.14 CDJ51979.1 - 4.4 6.1 7.6 4.4 6.1 7.6 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) CSG2 PF16965.5 CDJ51979.1 - 4.5 6.1 5.7 4.4 6.1 5.7 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Serinc PF03348.15 CDJ51979.1 - 5 6.0 8.8 4.7 6.0 8.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) CLN3 PF02487.17 CDJ51979.1 - 5.1 6.0 9.7 5 6.1 9.7 1.0 1 0 0 1 1 1 0 CLN3 protein Band_3_cyto PF07565.13 CDJ51979.1 - 5.4 6.7 11.0 5.3 6.8 11.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Baculo_PP31 PF05311.11 CDJ51979.1 - 5.5 6.4 12.3 5.5 6.4 12.3 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) eIF-3_zeta PF05091.12 CDJ51979.1 - 5.6 5.8 17.3 5.5 5.8 17.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ctr PF04145.15 CDJ51979.1 - 6.4 7.4 6.9 6.3 7.4 6.9 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DDHD PF02862.17 CDJ51979.1 - 7.3 6.7 13.1 7.2 6.7 13.1 1.0 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 CDJ51979.1 - 7.7 6.4 36.3 7.9 6.4 36.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ51979.1 - 8 7.1 22.9 8.6 7.0 22.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Androgen_recep PF02166.16 CDJ51979.1 - 9.6 4.9 40.3 10 4.8 40.3 1.0 1 0 0 1 1 1 0 Androgen receptor DUF4878 PF12870.7 CDJ51981.1 - 0.052 13.9 6.1 0.065 13.5 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) AAA_23 PF13476.6 CDJ51982.1 - 0.029 14.9 1.7 0.029 14.9 1.7 5.5 3 2 0 4 4 4 0 AAA domain Prefoldin_2 PF01920.20 CDJ51985.1 - 2e-05 24.5 15.4 2e-05 24.5 15.4 2.7 2 1 1 3 3 3 1 Prefoldin subunit NAGLU PF05089.12 CDJ51985.1 - 0.04 12.9 0.7 0.052 12.5 0.7 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain CCDC84 PF14968.6 CDJ51985.1 - 0.25 10.9 17.6 0.38 10.3 17.6 1.3 1 1 0 1 1 1 0 Coiled coil protein 84 DUF572 PF04502.13 CDJ51985.1 - 7.6 6.1 15.8 10 5.6 15.7 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF572) Ank_2 PF12796.7 CDJ51986.1 - 7.6e-14 52.1 0.9 1.7e-11 44.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ51986.1 - 2.8e-11 43.4 0.6 7e-10 39.0 0.3 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ51986.1 - 3.1e-11 43.6 1.9 3.1e-06 27.6 0.1 3.5 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ51986.1 - 1.8e-10 40.1 0.5 0.00031 21.0 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CDJ51986.1 - 4e-10 39.7 1.2 7.3e-06 26.2 0.2 3.4 3 0 0 3 3 3 2 Ankyrin repeat DUF2722 PF10846.8 CDJ51986.1 - 0.007 15.4 2.1 0.007 15.4 2.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) LUC7 PF03194.15 CDJ51986.1 - 0.024 14.3 13.5 0.017 14.8 2.4 2.1 2 0 0 2 2 2 0 LUC7 N_terminus Cwf_Cwc_15 PF04889.12 CDJ51986.1 - 0.59 9.8 13.4 0.34 10.6 1.2 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Activator_LAG-3 PF11498.8 CDJ51986.1 - 0.75 8.7 50.7 0.2 10.6 20.6 2.7 3 0 0 3 3 3 0 Transcriptional activator LAG-3 Mit_KHE1 PF10173.9 CDJ51986.1 - 0.84 9.7 5.9 3.4 7.7 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related EPL1 PF10513.9 CDJ51986.1 - 0.95 9.8 11.9 7.2 7.0 0.4 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Suf PF05843.14 CDJ51986.1 - 1.1 9.2 26.2 0.057 13.4 9.9 2.5 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Slu7 PF11708.8 CDJ51986.1 - 1.2 8.8 15.8 0.37 10.5 1.9 2.5 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor MMR1 PF08505.10 CDJ51986.1 - 1.3 9.3 16.6 1.9 8.7 1.1 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein EIF4E-T PF10477.9 CDJ51986.1 - 2.7 6.7 17.5 0.74 8.6 1.3 2.1 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PA26 PF04636.13 CDJ51986.1 - 4.6 6.0 10.4 4.3 6.1 1.9 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) RAB3GAP2_N PF14655.6 CDJ51986.1 - 6 6.0 12.1 2.3 7.4 0.8 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Connexin PF00029.19 CDJ51986.1 - 6.1 6.5 7.5 6 6.6 3.1 2.1 2 0 0 2 2 2 0 Connexin XRCC4 PF06632.12 CDJ51986.1 - 6.2 5.6 13.0 2.1 7.1 4.3 2.5 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PAS PF00989.25 CDJ51986.1 - 7 6.7 6.1 4.2 7.4 0.2 2.4 2 0 0 2 2 2 0 PAS fold DUF4770 PF15994.5 CDJ51986.1 - 9.7 6.4 14.0 18 5.5 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Macoilin PF09726.9 CDJ51988.1 - 0.004 15.8 9.4 0.0036 15.9 9.4 1.1 1 0 0 1 1 1 1 Macoilin family Apt1 PF10351.9 CDJ51988.1 - 0.032 13.1 8.6 0.033 13.1 8.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1635 PF07795.11 CDJ51988.1 - 0.033 14.1 12.5 0.046 13.6 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) SMN PF06003.12 CDJ51988.1 - 0.054 12.8 13.8 0.068 12.4 13.8 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Mcm10 PF09332.11 CDJ51988.1 - 0.074 12.5 9.9 0.074 12.5 9.9 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DDHD PF02862.17 CDJ51988.1 - 0.074 13.2 5.2 0.068 13.3 5.2 1.1 1 0 0 1 1 1 0 DDHD domain PNISR PF15996.5 CDJ51988.1 - 0.087 13.1 7.9 0.12 12.7 7.9 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR BAF1_ABF1 PF04684.13 CDJ51988.1 - 0.17 10.9 12.3 0.17 10.9 12.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Hid1 PF12722.7 CDJ51988.1 - 0.26 9.4 7.1 0.24 9.5 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SR-25 PF10500.9 CDJ51988.1 - 0.32 10.6 22.2 0.42 10.2 22.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Otopetrin PF03189.13 CDJ51988.1 - 0.35 9.7 3.2 0.36 9.6 3.2 1.0 1 0 0 1 1 1 0 Otopetrin Rib_recp_KP_reg PF05104.12 CDJ51988.1 - 0.36 11.9 35.4 0.52 11.3 35.4 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region EPL1 PF10513.9 CDJ51988.1 - 0.96 9.8 13.4 1.1 9.6 13.4 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF4614 PF15391.6 CDJ51988.1 - 1.3 9.0 15.3 1.7 8.6 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Spt20 PF12090.8 CDJ51988.1 - 1.8 8.1 29.0 2.5 7.7 29.0 1.1 1 0 0 1 1 1 0 Spt20 family NST1 PF13945.6 CDJ51988.1 - 1.8 8.6 21.7 2.3 8.3 21.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator SRP-alpha_N PF04086.13 CDJ51988.1 - 2.3 8.1 14.4 2.7 7.8 14.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4813 PF16072.5 CDJ51988.1 - 3.2 7.3 53.5 4.2 6.9 53.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) SOBP PF15279.6 CDJ51988.1 - 3.5 8.2 18.9 4.2 7.9 18.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein FAM76 PF16046.5 CDJ51988.1 - 3.7 6.8 13.4 4.2 6.6 13.4 1.0 1 0 0 1 1 1 0 FAM76 protein DUF4746 PF15928.5 CDJ51988.1 - 4.2 6.7 10.2 5.2 6.4 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SKA1 PF07160.12 CDJ51988.1 - 4.4 7.1 11.3 5.2 6.9 11.3 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF755 PF05501.11 CDJ51988.1 - 4.7 7.5 29.6 6 7.2 29.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF702 PF05142.12 CDJ51988.1 - 6.2 7.3 10.6 8.2 6.9 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) FAM176 PF14851.6 CDJ51988.1 - 6.7 6.4 7.1 8.7 6.0 7.1 1.1 1 0 0 1 1 1 0 FAM176 family MPM1 PF17234.2 CDJ51988.1 - 7.5 6.8 15.1 9 6.5 15.1 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Rtf2 PF04641.12 CDJ51988.1 - 7.5 5.8 15.8 10 5.4 15.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger ANAPC_CDC26 PF10471.9 CDJ51988.1 - 7.6 7.5 17.7 17 6.3 17.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 NPR3 PF03666.13 CDJ51988.1 - 8.1 5.1 14.7 9.6 4.9 14.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 CDJ51988.1 - 8.3 6.4 12.4 9.7 6.1 12.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Mem_trans PF03547.18 CDJ51988.1 - 9.8 4.4 9.2 12 4.2 9.2 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF2339 PF10101.9 CDJ51989.1 - 0.25 9.9 9.6 0.3 9.6 9.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) CDC45 PF02724.14 CDJ51989.1 - 1.1 7.5 27.6 1.2 7.4 27.6 1.3 1 0 0 1 1 1 0 CDC45-like protein CD20 PF04103.15 CDJ51989.1 - 2.7 8.1 10.8 74 3.4 10.8 2.4 1 1 0 1 1 1 0 CD20-like family Miga PF10265.9 CDJ51989.1 - 3.1 6.7 19.5 3.8 6.4 19.5 1.3 1 0 0 1 1 1 0 Mitoguardin GAGA_bind PF06217.12 CDJ51989.1 - 3.3 7.9 38.7 3.8 7.7 38.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family VIR_N PF15912.5 CDJ51989.1 - 8.4 5.9 19.6 10 5.6 19.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal MelC1 PF06236.11 CDJ51991.1 - 0.00032 20.8 1.9 0.00032 20.8 1.9 2.7 3 0 0 3 3 3 1 Tyrosinase co-factor MelC1 RPN2_C PF18004.1 CDJ51991.1 - 0.078 12.9 2.7 0.15 12.0 2.7 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3446 PF11928.8 CDJ51991.1 - 3.6 8.0 16.3 0.96 9.8 6.5 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF3597 PF12200.8 CDJ51991.1 - 4 8.0 9.1 11 6.6 4.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3597) DUF2057 PF09829.9 CDJ51991.1 - 5.9 7.0 11.9 5.4 7.1 4.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Suf PF05843.14 CDJ51992.1 - 0.00025 21.1 3.5 0.00044 20.3 3.5 1.4 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) CD20 PF04103.15 CDJ51992.1 - 0.038 14.1 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 CD20-like family DUF872 PF05915.12 CDJ51992.1 - 0.22 11.7 0.6 0.68 10.1 0.1 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Velvet PF11754.8 CDJ51992.1 - 0.28 11.1 9.3 0.41 10.5 8.6 1.5 1 1 0 1 1 1 0 Velvet factor DUF3357 PF11837.8 CDJ51992.1 - 0.65 10.5 0.0 0.65 10.5 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3357) Tmemb_9 PF05434.11 CDJ51992.1 - 1.6 8.6 7.9 12 5.8 0.2 2.4 2 0 0 2 2 2 0 TMEM9 Presenilin PF01080.17 CDJ51992.1 - 2.8 6.6 13.1 1.4 7.6 9.6 2.1 2 0 0 2 2 2 0 Presenilin CAF1 PF04857.20 CDJ51992.1 - 6.5 5.8 14.2 29 3.7 14.1 1.9 1 1 0 1 1 1 0 CAF1 family ribonuclease GET2 PF08690.10 CDJ51992.1 - 7.5 6.1 14.5 0.81 9.3 10.3 1.5 2 0 0 2 2 2 0 GET complex subunit GET2 DUF4598 PF15370.6 CDJ51992.1 - 7.6 7.1 14.8 0.51 10.8 3.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4598) TMEM51 PF15345.6 CDJ51992.1 - 8.4 6.2 10.0 2.8 7.7 6.7 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 CDC24_OB1 PF17246.2 CDJ51993.1 - 0.016 15.3 0.6 0.045 13.9 0.6 1.8 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 1 DUF1340 PF07067.11 CDJ51993.1 - 0.091 12.1 0.9 13 5.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1340) GSH-S_N PF02951.14 CDJ51993.1 - 0.22 11.7 3.5 1.3 9.2 3.5 2.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Baculo_PP31 PF05311.11 CDJ51993.1 - 2.1 7.8 10.3 4.9 6.6 10.3 1.6 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Suf PF05843.14 CDJ51994.1 - 1.7 8.5 6.2 1.7 8.6 6.2 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ51994.1 - 3.4 7.2 15.1 4 7.0 15.1 1.1 1 0 0 1 1 1 0 Spt20 family Gp5_C PF06715.12 CDJ51995.1 - 0.0013 18.7 0.2 0.0041 17.2 0.0 1.9 2 0 0 2 2 2 1 Gp5 C-terminal repeat (3 copies) Suf PF05843.14 CDJ51995.1 - 7.4 6.5 17.0 10 6.0 17.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3800 PF12686.7 CDJ51996.1 - 4.6 7.9 13.6 1.8e+04 -5.8 13.9 5.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Macoilin PF09726.9 CDJ51997.1 - 0.0002 20.1 30.7 0.0002 20.1 30.7 3.0 3 0 0 3 3 2 2 Macoilin family Spt20 PF12090.8 CDJ51997.1 - 0.0011 18.7 12.4 0.0011 18.7 12.4 3.2 2 1 0 2 2 1 1 Spt20 family HHH_5 PF14520.6 CDJ51997.1 - 0.0022 18.5 0.1 0.0022 18.5 0.1 1.9 2 0 0 2 2 1 1 Helix-hairpin-helix domain DUF1645 PF07816.11 CDJ51997.1 - 0.011 16.3 3.4 0.011 16.3 3.4 4.4 3 1 0 3 3 2 0 Protein of unknown function (DUF1645) Nha1_C PF08619.10 CDJ51997.1 - 0.033 13.4 32.9 0.0055 16.0 23.6 2.3 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF572 PF04502.13 CDJ51997.1 - 0.35 10.5 33.6 0.2 11.2 23.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Lin-8 PF03353.15 CDJ51997.1 - 0.61 9.6 45.0 1.4 8.4 7.6 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TT_ORF1 PF02956.14 CDJ51997.1 - 1.3 7.7 15.2 4.3 5.9 11.9 2.1 2 0 0 2 2 2 0 TT viral orf 1 MCU PF04678.13 CDJ51997.1 - 1.9 8.6 11.9 7.1 6.7 1.6 2.6 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF4746 PF15928.5 CDJ51997.1 - 2.4 7.5 17.0 2.1 7.7 11.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Plasmodium_Vir PF05795.11 CDJ51997.1 - 2.8 7.2 26.6 0.39 10.1 16.2 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein PIG-S PF10510.9 CDJ51997.1 - 3.1 6.5 32.6 1.6 7.5 5.8 2.3 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein Pet20 PF08692.10 CDJ51997.1 - 3.3 8.4 14.0 0.66 10.7 5.3 2.6 2 0 0 2 2 2 0 Mitochondrial protein Pet20 DUF4457 PF14652.6 CDJ51997.1 - 4.9 6.3 12.5 7.9 5.6 5.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4457) MAP65_ASE1 PF03999.12 CDJ51997.1 - 5.7 5.5 40.3 0.29 9.8 26.5 2.2 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Nop25 PF09805.9 CDJ51997.1 - 6.9 7.1 28.1 1.4 9.4 18.8 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) TFIIF_alpha PF05793.12 CDJ51997.1 - 8.2 4.9 28.2 18 3.8 28.2 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IMS PF00817.20 CDJ51998.1 - 6.7e-15 55.4 0.0 7.8e-13 48.7 0.0 2.3 2 0 0 2 2 2 2 impB/mucB/samB family RskA PF10099.9 CDJ51998.1 - 1.8e-05 25.1 4.3 1.8e-05 25.1 4.3 4.3 2 2 1 3 3 3 1 Anti-sigma-K factor rskA Exonuc_VII_L PF02601.15 CDJ51998.1 - 0.00089 18.9 17.1 0.00089 18.9 17.1 2.1 2 0 0 2 2 2 1 Exonuclease VII, large subunit SUIM_assoc PF16619.5 CDJ51998.1 - 0.0073 16.4 1.1 0.0073 16.4 1.1 7.9 5 2 0 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 CDJ51999.1 - 2.4e-18 65.7 0.0 1.5e-09 37.5 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ51999.1 - 0.00028 20.7 0.0 0.49 10.3 0.0 2.5 2 1 0 2 2 2 2 Occluded RNA-recognition motif CHASE8 PF17152.4 CDJ51999.1 - 0.073 13.3 0.0 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Periplasmic sensor domain RRM_5 PF13893.6 CDJ51999.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fusion_gly PF00523.18 CDJ52000.1 - 0.67 8.1 3.4 1 7.5 3.4 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Prenyltrans PF00432.21 CDJ52001.1 - 7.7e-43 143.9 21.0 8.7e-10 38.2 0.0 6.5 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CDJ52001.1 - 4.2e-06 26.1 0.0 0.0028 16.8 0.0 3.5 1 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain PC_rep PF01851.22 CDJ52001.1 - 0.086 13.3 0.0 0.26 11.8 0.0 1.9 1 0 0 1 1 1 0 Proteasome/cyclosome repeat MFS_1 PF07690.16 CDJ52002.1 - 1.3e-17 63.8 21.6 4.9e-13 48.7 6.3 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily CDC50 PF03381.15 CDJ52003.1 - 5.4e-62 209.9 0.0 7.7e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Mlo PF03094.15 CDJ52004.1 - 2.7e-05 22.7 11.4 7.1e-05 21.4 3.7 3.0 1 1 2 3 3 3 2 Mlo family EF-hand_6 PF13405.6 CDJ52004.1 - 0.00027 20.6 1.6 0.001 18.8 1.6 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CDJ52004.1 - 0.005 17.3 0.1 0.019 15.4 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ52004.1 - 0.011 15.3 1.1 0.038 13.5 1.1 2.0 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 CDJ52004.1 - 0.028 14.3 1.7 0.059 13.2 1.7 1.5 1 0 0 1 1 1 0 EF-hand domain pair Baculo_VP91_N PF08475.10 CDJ52004.1 - 0.029 14.1 0.8 0.29 10.8 1.2 2.2 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal Baculo_11_kDa PF06143.11 CDJ52004.1 - 4.1 7.1 6.0 9.8 5.8 1.2 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family DFP PF04127.15 CDJ52005.1 - 2.5e-11 43.7 21.3 1e-08 35.3 0.0 4.4 4 0 0 4 4 4 3 DNA / pantothenate metabolism flavoprotein Peptidase_S49_N PF08496.10 CDJ52005.1 - 0.078 13.0 15.2 0.78 9.8 1.3 3.2 3 0 0 3 3 3 0 Peptidase family S49 N-terminal CSG2 PF16965.5 CDJ52005.1 - 0.18 10.7 7.1 2.2 7.1 0.6 2.3 2 0 0 2 2 2 0 Ceramide synthase regulator Na_trans_assoc PF06512.13 CDJ52005.1 - 0.23 11.7 10.2 0.21 11.9 1.0 2.4 2 0 0 2 2 2 0 Sodium ion transport-associated Otopetrin PF03189.13 CDJ52005.1 - 0.55 9.0 6.3 1.7 7.3 0.2 2.3 2 0 0 2 2 2 0 Otopetrin SAPS PF04499.15 CDJ52005.1 - 2.4 6.8 17.2 0.25 10.1 2.4 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 CDJ52005.1 - 2.4 7.1 23.7 0.36 9.8 7.3 2.4 2 0 0 2 2 2 0 Solute carrier family 12 CLN3 PF02487.17 CDJ52005.1 - 7.9 5.4 19.8 0.02 14.0 0.9 2.9 2 1 0 2 2 2 0 CLN3 protein TPR_1 PF00515.28 CDJ52006.1 - 6e-10 38.5 0.9 0.00038 20.2 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ52006.1 - 1.1e-06 28.3 0.8 0.035 14.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ52006.1 - 4.6e-05 23.0 0.2 0.11 12.2 0.0 2.7 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 CDJ52006.1 - 0.0011 19.0 0.1 1.1 9.6 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF4366 PF14283.6 CDJ52006.1 - 0.0046 17.0 0.4 0.0046 17.0 0.4 4.1 2 2 1 3 3 3 1 Domain of unknown function (DUF4366) BUD22 PF09073.10 CDJ52006.1 - 0.028 13.8 45.8 0.015 14.6 20.0 2.3 2 0 0 2 2 2 0 BUD22 BAF1_ABF1 PF04684.13 CDJ52006.1 - 5 6.1 42.5 2.2 7.3 23.9 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Plasmodium_Vir PF05795.11 CDJ52006.1 - 5.6 6.3 29.4 2.7 7.3 7.8 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Med15 PF09606.10 CDJ52006.1 - 9.4 4.8 77.4 1.2 7.7 57.6 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PTPA PF03095.15 CDJ52007.1 - 1.7e-28 100.0 0.1 8.1e-25 87.9 0.1 6.1 4 2 1 5 5 5 2 Phosphotyrosyl phosphate activator (PTPA) protein Utp14 PF04615.13 CDJ52007.1 - 3.6e-05 22.6 9.9 3.6e-05 22.6 9.9 7.3 1 1 7 8 8 8 1 Utp14 protein MIP PF00230.20 CDJ52009.1 - 2.3e-15 56.9 38.7 5.4e-07 29.6 17.0 3.9 1 1 2 3 3 3 3 Major intrinsic protein DUF2304 PF10066.9 CDJ52009.1 - 0.52 10.5 3.1 0.66 10.2 0.8 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Prot_ATP_ID_OB PF16450.5 CDJ52010.1 - 3.4e-08 33.3 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AIF_C PF14721.6 CDJ52010.1 - 0.3 11.4 3.9 0.12 12.7 1.0 1.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Hydin_ADK PF17213.3 CDJ52010.1 - 0.67 10.2 5.8 1.2 9.4 5.8 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Spt20 PF12090.8 CDJ52010.1 - 6.3 6.3 24.0 0.41 10.2 17.9 1.9 2 1 0 2 2 2 0 Spt20 family Androgen_recep PF02166.16 CDJ52010.1 - 8.2 5.1 12.4 16 4.2 12.4 1.5 1 0 0 1 1 1 0 Androgen receptor SPAN PF02510.14 CDJ52010.1 - 9.8 5.2 10.3 15 4.6 10.3 1.3 1 0 0 1 1 1 0 Surface presentation of antigens protein DUF1645 PF07816.11 CDJ52011.1 - 0.0026 18.4 25.0 0.0026 18.4 25.0 6.2 6 2 0 6 6 6 3 Protein of unknown function (DUF1645) DUF2722 PF10846.8 CDJ52011.1 - 0.0044 16.0 2.0 0.0044 16.0 2.0 7.9 3 3 2 5 5 5 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ52011.1 - 0.0052 16.8 22.8 0.0052 16.8 22.8 5.5 2 1 3 5 5 5 1 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 CDJ52012.1 - 2.1e-05 23.9 3.5 2.8e-05 23.5 3.5 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter CDC45 PF02724.14 CDJ52012.1 - 0.00039 18.9 15.2 0.00057 18.3 15.2 1.2 1 0 0 1 1 1 1 CDC45-like protein Sin_N PF04801.13 CDJ52012.1 - 0.0005 19.4 21.9 0.00071 18.9 21.9 1.5 1 0 0 1 1 1 1 Sin-like protein conserved region Endostatin PF06482.11 CDJ52012.1 - 0.0016 17.9 12.6 0.0024 17.4 12.6 1.4 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin SLC12 PF03522.15 CDJ52012.1 - 0.0021 17.2 16.1 0.0029 16.7 16.1 1.3 1 0 0 1 1 1 1 Solute carrier family 12 PAT1 PF09770.9 CDJ52012.1 - 0.0034 15.7 34.1 0.0041 15.5 34.1 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.12 CDJ52012.1 - 0.0039 17.5 10.8 0.0056 17.0 10.8 1.4 1 0 0 1 1 1 1 GAGA binding protein-like family DUF2828 PF11443.8 CDJ52012.1 - 0.0065 14.6 13.3 0.0087 14.2 13.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) PA26 PF04636.13 CDJ52012.1 - 0.015 14.2 9.0 0.02 13.8 9.0 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SARAF PF06682.12 CDJ52012.1 - 0.015 14.9 13.6 0.024 14.3 13.6 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Lin-8 PF03353.15 CDJ52012.1 - 0.02 14.5 23.6 0.031 13.8 23.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CSG2 PF16965.5 CDJ52012.1 - 0.023 13.7 10.2 0.044 12.7 10.2 1.5 1 0 0 1 1 1 0 Ceramide synthase regulator SID-1_RNA_chan PF13965.6 CDJ52012.1 - 0.031 12.7 4.7 0.04 12.3 4.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RPOL_N PF14700.6 CDJ52012.1 - 0.044 13.2 22.3 0.084 12.3 22.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Raftlin PF15250.6 CDJ52012.1 - 0.057 12.2 14.3 0.1 11.3 14.3 1.5 1 0 0 1 1 1 0 Raftlin GREB1 PF15782.5 CDJ52012.1 - 0.067 10.3 19.3 0.078 10.1 19.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Tim54 PF11711.8 CDJ52012.1 - 0.091 11.5 19.7 0.2 10.4 19.7 1.6 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Dicty_REP PF05086.12 CDJ52012.1 - 0.11 10.5 9.1 0.12 10.4 9.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PNISR PF15996.5 CDJ52012.1 - 0.11 12.7 28.1 0.02 15.2 22.9 2.2 2 1 0 2 2 2 0 Arginine/serine-rich protein PNISR DUF4746 PF15928.5 CDJ52012.1 - 0.14 11.5 19.0 0.27 10.6 19.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MDM10 PF12519.8 CDJ52012.1 - 0.16 10.8 15.0 0.23 10.3 15.0 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Peptidase_S64 PF08192.11 CDJ52012.1 - 0.17 10.3 15.7 0.26 9.7 15.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 CCSAP PF15748.5 CDJ52012.1 - 0.23 11.6 28.3 0.031 14.4 24.0 1.8 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated CDK5_activator PF03261.15 CDJ52012.1 - 0.27 10.7 14.2 0.44 10.0 14.2 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4050 PF13259.6 CDJ52012.1 - 0.29 11.4 19.0 0.29 11.4 16.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Peroxin-3 PF04882.12 CDJ52012.1 - 0.31 10.0 20.6 0.18 10.8 17.9 1.9 2 0 0 2 2 2 0 Peroxin-3 DUF4638 PF15472.6 CDJ52012.1 - 0.36 10.5 15.1 0.59 9.8 15.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Otopetrin PF03189.13 CDJ52012.1 - 0.51 9.1 8.9 0.81 8.4 8.9 1.4 1 0 0 1 1 1 0 Otopetrin BNIP2 PF12496.8 CDJ52012.1 - 0.53 10.7 11.3 1.4 9.4 11.3 1.7 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 TCP PF03634.13 CDJ52012.1 - 0.54 10.8 24.7 1.1 9.8 24.7 1.8 1 1 0 1 1 1 0 TCP family transcription factor CRT10 PF08728.10 CDJ52012.1 - 0.61 8.2 7.9 0.76 7.9 7.9 1.1 1 0 0 1 1 1 0 CRT10 V_ATPase_I PF01496.19 CDJ52012.1 - 0.65 7.8 25.3 1.1 7.0 25.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Afi1 PF07792.12 CDJ52012.1 - 0.7 10.4 21.1 1.8 9.0 21.1 1.7 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 CDJ52012.1 - 0.79 8.4 31.9 0.077 11.8 27.2 1.6 2 0 0 2 2 2 0 Presenilin LMBR1 PF04791.16 CDJ52012.1 - 1.3 7.9 8.4 1.7 7.4 8.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2151 PF10221.9 CDJ52012.1 - 1.3 7.5 14.9 0.74 8.3 13.3 1.4 2 0 0 2 2 2 0 Cell cycle and development regulator RR_TM4-6 PF06459.12 CDJ52012.1 - 1.7 8.4 35.7 0.78 9.5 31.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 CDJ52012.1 - 3.3 7.2 21.1 6.7 6.1 21.1 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4569 PF15133.6 CDJ52012.1 - 4.4 6.9 26.7 1.1 8.9 23.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) MCM_bind PF09739.9 CDJ52012.1 - 5 5.4 24.6 7.7 4.8 24.6 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PTS_EIIC PF02378.18 CDJ52012.1 - 9.8 5.1 8.4 2.2 7.2 1.0 2.3 2 0 0 2 2 2 0 Phosphotransferase system, EIIC PPTA PF01239.22 CDJ52013.1 - 0.0071 16.0 0.7 0.019 14.7 0.7 1.7 1 0 0 1 1 1 1 Protein prenyltransferase alpha subunit repeat Membr_traf_MHD PF10540.9 CDJ52013.1 - 0.022 14.9 0.3 0.022 14.9 0.3 3.2 4 0 0 4 4 4 0 Munc13 (mammalian uncoordinated) homology domain DUF4770 PF15994.5 CDJ52013.1 - 0.82 9.9 27.5 0.11 12.7 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) BAF1_ABF1 PF04684.13 CDJ52013.1 - 8.7 5.3 31.9 0.47 9.5 21.5 2.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Ribosomal_L14e PF01929.17 CDJ52015.1 - 6.8e-30 103.4 4.5 9.5e-30 102.9 4.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CDJ52015.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 KOW motif ER_lumen_recept PF00810.18 CDJ52016.1 - 2.4e-24 86.8 5.2 4.9e-24 85.8 5.2 1.5 1 1 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CDJ52016.1 - 0.57 10.0 10.0 0.45 10.3 0.6 4.4 4 1 0 4 4 4 0 PQ loop repeat SLATT_5 PF18160.1 CDJ52016.1 - 2.8 7.2 8.0 0.062 12.6 1.0 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 EMP70 PF02990.16 CDJ52017.1 - 1.4e-67 228.6 0.0 5.8e-67 226.5 0.0 2.0 1 1 0 1 1 1 1 Endomembrane protein 70 CopD PF05425.13 CDJ52017.1 - 0.76 10.2 7.8 4.9 7.6 5.7 2.2 2 0 0 2 2 2 0 Copper resistance protein D Presenilin PF01080.17 CDJ52018.1 - 0.0047 15.7 22.6 0.0056 15.5 22.6 1.2 1 0 0 1 1 1 1 Presenilin Spt20 PF12090.8 CDJ52018.1 - 0.0058 16.3 20.4 0.0058 16.3 20.4 2.2 2 0 0 2 2 2 1 Spt20 family MAM33 PF02330.16 CDJ52018.1 - 0.015 15.3 22.2 0.02 14.8 9.4 2.1 2 0 0 2 2 2 0 Mitochondrial glycoprotein FAM176 PF14851.6 CDJ52018.1 - 0.031 13.9 13.3 0.32 10.7 1.2 2.1 2 0 0 2 2 2 0 FAM176 family DUF3408 PF11888.8 CDJ52018.1 - 0.04 14.0 27.2 0.076 13.2 13.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF2722 PF10846.8 CDJ52018.1 - 0.055 12.4 49.5 0.39 9.6 24.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ52018.1 - 0.24 11.8 24.4 0.68 10.3 10.4 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF4834 PF16118.5 CDJ52018.1 - 0.3 12.1 29.5 0.62 11.1 6.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SpoIIP PF07454.11 CDJ52018.1 - 0.5 9.8 27.5 1.4 8.3 5.9 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Apc15p PF05841.11 CDJ52018.1 - 0.61 10.9 29.8 1 10.2 13.3 2.3 2 0 0 2 2 2 0 Apc15p protein RPA43_OB PF17875.1 CDJ52018.1 - 0.67 10.6 17.1 2.1 9.0 5.9 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I PTPRCAP PF15713.5 CDJ52018.1 - 0.9 9.8 28.4 0.68 10.2 6.5 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Eapp_C PF10238.9 CDJ52018.1 - 0.96 9.5 27.6 1.7 8.7 12.3 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF2052 PF09747.9 CDJ52018.1 - 1.1 9.4 24.0 1.4 9.0 7.3 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) MecA PF05389.12 CDJ52018.1 - 1.1 8.9 21.5 2.8 7.5 11.6 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF1764 PF08576.10 CDJ52018.1 - 1.4 9.9 22.9 0.95 10.4 9.8 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF4175 PF13779.6 CDJ52018.1 - 1.6 6.6 57.9 1.6 6.5 24.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) RR_TM4-6 PF06459.12 CDJ52018.1 - 1.6 8.5 27.3 3 7.6 13.9 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 CDJ52018.1 - 1.7 8.0 39.5 1.7 7.9 15.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RPN2_C PF18004.1 CDJ52018.1 - 2.1 8.3 24.1 1.7 8.5 10.1 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Thg1C PF14413.6 CDJ52018.1 - 2.1 8.5 18.2 4.1 7.6 9.1 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain Afi1 PF07792.12 CDJ52018.1 - 2.3 8.7 21.2 4.5 7.7 8.8 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FmiP_Thoc5 PF09766.9 CDJ52018.1 - 2.3 7.4 31.0 0.83 8.9 14.5 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Rxt3 PF08642.10 CDJ52018.1 - 2.3 9.0 14.8 6.5 7.5 7.0 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 EFTUD2 PF16004.5 CDJ52018.1 - 2.4 8.7 24.5 3.9 8.1 9.9 2.2 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF702 PF05142.12 CDJ52018.1 - 2.5 8.5 26.6 3.1 8.2 11.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Pap_E4 PF02711.14 CDJ52018.1 - 2.7 9.0 20.5 2 9.4 0.7 2.3 2 0 0 2 2 2 0 E4 protein XAP5 PF04921.14 CDJ52018.1 - 2.7 7.7 18.4 2.4 7.9 6.8 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator NST1 PF13945.6 CDJ52018.1 - 3 7.9 36.4 2.5 8.2 15.2 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator CTU2 PF10288.9 CDJ52018.1 - 3.2 8.0 21.2 4.6 7.5 2.9 2.4 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 PRC2_HTH_1 PF18118.1 CDJ52018.1 - 3.3 8.6 19.4 4 8.3 8.7 2.2 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Tim54 PF11711.8 CDJ52018.1 - 3.9 6.2 22.7 3 6.5 11.3 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4551 PF15087.6 CDJ52018.1 - 4.4 6.0 21.1 5.7 5.7 21.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF1644 PF07800.12 CDJ52018.1 - 4.8 7.2 14.3 10 6.2 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) YABBY PF04690.13 CDJ52018.1 - 5.4 7.6 18.2 11 6.6 9.9 2.1 2 0 0 2 2 2 0 YABBY protein Peroxin-13_N PF04088.13 CDJ52018.1 - 6 7.1 17.3 5.8 7.2 8.3 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Slu7 PF11708.8 CDJ52018.1 - 6.4 6.4 25.9 4.2 7.1 10.0 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor DUF4820 PF16091.5 CDJ52018.1 - 7.2 5.9 21.5 2.8 7.3 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF3464 PF11947.8 CDJ52018.1 - 7.3 6.3 30.5 4.5 7.0 5.4 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Renin_r PF07850.14 CDJ52018.1 - 9 7.0 15.0 0.27 11.8 4.4 2.3 2 0 0 2 2 2 0 Renin receptor-like protein EIIBC-GUT_N PF03612.14 CDJ52018.1 - 9.1 6.0 27.2 1.8 8.3 10.8 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DDRGK PF09756.9 CDJ52018.1 - 9.7 5.7 34.1 0.75 9.4 14.6 2.1 2 0 0 2 2 2 0 DDRGK domain Skp1_POZ PF03931.15 CDJ52019.1 - 1.6e-08 34.6 0.0 3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Patatin PF01734.22 CDJ52020.1 - 4.3e-26 92.4 3.0 4.3e-26 92.4 3.0 8.1 6 3 0 6 6 6 1 Patatin-like phospholipase Mitofilin PF09731.9 CDJ52021.1 - 0.035 12.9 15.2 0.043 12.7 15.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3573 PF12097.8 CDJ52021.1 - 0.12 11.2 2.1 0.12 11.1 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) PTS_IIA PF02255.16 CDJ52021.1 - 0.43 10.7 9.5 1.3 9.1 9.5 1.8 1 1 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF4407 PF14362.6 CDJ52021.1 - 0.98 8.7 12.3 1.1 8.5 12.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.11 CDJ52021.1 - 1.1 7.7 16.5 1.3 7.5 16.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein OmpH PF03938.14 CDJ52021.1 - 2.5 8.5 18.3 3 8.2 18.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PDDEXK_6 PF04720.12 CDJ52021.1 - 2.7 7.9 11.4 3.2 7.6 11.4 1.0 1 0 0 1 1 1 0 PDDEXK-like family of unknown function V_ATPase_I PF01496.19 CDJ52021.1 - 3.9 5.3 8.4 4.2 5.2 8.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 CDJ52021.1 - 5 6.3 9.4 5.3 6.2 9.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein FemAB PF02388.16 CDJ52021.1 - 6.4 5.5 13.8 7.1 5.4 13.8 1.0 1 0 0 1 1 1 0 FemAB family CENP-I PF07778.11 CDJ52021.1 - 10 4.7 6.8 11 4.6 6.8 1.0 1 0 0 1 1 1 0 Mis6 NAD_binding_8 PF13450.6 CDJ52022.1 - 2.6e-08 34.0 0.1 2.6e-08 34.0 0.1 5.5 7 0 0 7 7 7 1 NAD(P)-binding Rossmann-like domain DUF2722 PF10846.8 CDJ52022.1 - 7.4e-06 25.2 5.3 7.4e-06 25.2 5.3 4.9 6 1 0 6 6 6 2 Protein of unknown function (DUF2722) MCRA PF06100.11 CDJ52022.1 - 3.4e-05 22.8 0.0 7.5e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 MCRA family SPX PF03105.19 CDJ52022.1 - 0.0017 18.3 11.3 0.0017 18.3 11.3 3.4 3 1 0 3 3 3 1 SPX domain Thi4 PF01946.17 CDJ52022.1 - 0.0086 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Connexin PF00029.19 CDJ52022.1 - 0.24 11.1 7.4 2.5 7.8 0.5 2.4 2 0 0 2 2 2 0 Connexin EOS1 PF12326.8 CDJ52022.1 - 0.24 11.3 6.3 6.7 6.6 0.1 2.8 1 1 1 2 2 2 0 N-glycosylation protein RICTOR_N PF14664.6 CDJ52022.1 - 1.1 8.2 9.4 0.063 12.2 0.7 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Mlh1_C PF16413.5 CDJ52022.1 - 7.8 5.8 12.3 1.4 8.2 0.6 3.1 3 0 0 3 3 3 0 DNA mismatch repair protein Mlh1 C-terminus EPL1 PF10513.9 CDJ52022.1 - 9.8 6.5 27.4 0.53 10.6 2.8 3.9 3 0 0 3 3 3 0 Enhancer of polycomb-like PseudoU_synth_1 PF01416.20 CDJ52024.1 - 2.5e-12 47.2 11.6 1.6e-11 44.6 0.0 3.7 3 1 0 3 3 3 2 tRNA pseudouridine synthase SR-25 PF10500.9 CDJ52024.1 - 2.3e-06 27.4 14.6 2.3e-06 27.4 14.6 4.4 4 1 2 6 6 6 1 Nuclear RNA-splicing-associated protein SET PF00856.28 CDJ52025.1 - 1.3e-07 32.1 0.0 1.3e-07 32.1 0.0 4.9 2 1 0 3 3 3 1 SET domain Rgp1 PF08737.10 CDJ52025.1 - 0.013 14.7 0.5 0.013 14.7 0.5 4.2 3 2 1 4 4 4 0 Rgp1 Pheromone PF08015.11 CDJ52027.1 - 1 10.4 6.0 18 6.5 1.1 2.6 2 0 0 2 2 2 0 Fungal mating-type pheromone Dehydrin PF00257.19 CDJ52027.1 - 2.3 8.7 13.0 0.053 14.1 2.5 2.2 2 0 0 2 2 2 0 Dehydrin RskA PF10099.9 CDJ52027.1 - 4.7 7.5 28.3 0.65 10.3 13.2 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ52028.1 - 0.011 15.4 15.2 0.011 15.4 15.2 4.1 3 1 1 4 4 4 0 Nuclear RNA-splicing-associated protein Utp14 PF04615.13 CDJ52028.1 - 0.77 8.3 29.0 0.33 9.5 5.6 2.3 2 0 0 2 2 2 0 Utp14 protein DUF4834 PF16118.5 CDJ52028.1 - 6 7.9 0.0 6 7.9 0.0 6.9 3 2 2 5 5 5 0 Domain of unknown function (DUF4834) Bax1-I PF01027.20 CDJ52029.1 - 2.6e-22 79.7 25.5 1.1e-21 77.7 25.5 1.7 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Zip PF02535.22 CDJ52029.1 - 0.00051 19.4 15.4 0.00052 19.3 14.1 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter O-antigen_lig PF13425.6 CDJ52029.1 - 0.0018 17.1 2.4 0.0018 17.1 2.4 1.8 2 0 0 2 2 2 1 O-antigen ligase like membrane protein Hid1 PF12722.7 CDJ52029.1 - 0.0086 14.3 10.3 0.011 13.9 10.3 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein MAJIN PF15077.6 CDJ52029.1 - 0.39 10.5 11.3 0.58 9.9 11.3 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein SLC12 PF03522.15 CDJ52029.1 - 0.98 8.4 17.2 1.3 8.0 17.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 CDJ52029.1 - 1.3 7.7 14.4 1.8 7.3 14.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_M3_N PF08439.10 CDJ52030.1 - 0.096 13.0 0.2 0.89 9.9 0.1 2.5 2 0 0 2 2 2 0 Oligopeptidase F EDR1 PF14381.6 CDJ52030.1 - 1.3 8.7 4.3 1.1 9.0 0.2 2.8 2 1 1 3 3 3 0 Ethylene-responsive protein kinase Le-CTR1 DUF2459 PF09601.10 CDJ52030.1 - 2.4 7.9 9.1 0.55 10.0 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) Glyco_transf_5 PF08323.11 CDJ52032.1 - 2.7e-21 76.4 0.0 8.5e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 Starch synthase catalytic domain AMPK1_CBM PF16561.5 CDJ52032.1 - 7.1e-17 61.4 0.0 1.9e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glycos_transf_1 PF00534.20 CDJ52032.1 - 1.2e-10 41.2 0.0 3.5e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ52032.1 - 1.5e-06 28.7 0.0 1.5e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF2722 PF10846.8 CDJ52032.1 - 0.00072 18.6 6.3 0.00072 18.6 6.3 13.9 9 4 4 13 13 13 4 Protein of unknown function (DUF2722) Peptidase_S66C PF17676.1 CDJ52032.1 - 0.036 14.6 0.2 0.17 12.4 0.2 2.2 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain Porphobil_deam PF01379.20 CDJ52033.1 - 5.5e-44 150.1 14.0 1.3e-38 132.6 8.8 4.2 2 1 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CDJ52033.1 - 1.7e-12 47.5 0.0 1.4e-11 44.6 0.0 2.5 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Spt20 PF12090.8 CDJ52033.1 - 0.0098 15.5 8.9 0.0098 15.5 8.9 3.9 3 1 0 3 3 3 1 Spt20 family SR-25 PF10500.9 CDJ52033.1 - 7.5 6.1 19.4 0.41 10.2 12.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 CDJ52034.1 - 1.1e-65 221.7 0.0 1.3e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ52034.1 - 8.6e-35 120.3 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ52034.1 - 5.8e-08 32.4 0.0 1.4e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ52034.1 - 0.00098 18.5 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ52034.1 - 0.0052 15.8 0.1 0.0083 15.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ52034.1 - 0.0083 16.1 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 CDJ52034.1 - 0.02 14.4 0.1 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL YukC PF10140.9 CDJ52034.1 - 0.092 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC AdenylateSensor PF16579.5 CDJ52034.1 - 0.13 12.7 0.0 4.2 7.9 0.0 2.8 1 1 1 2 2 2 0 Adenylate sensor of SNF1-like protein kinase Choline_kinase PF01633.20 CDJ52034.1 - 0.17 11.4 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SR-25 PF10500.9 CDJ52034.1 - 1.3 8.5 6.1 2.8 7.5 6.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rubella_Capsid PF05750.11 CDJ52035.1 - 0.94 9.0 6.8 1.1 8.9 6.8 1.1 1 0 0 1 1 1 0 Rubella capsid protein TMEM247 PF15444.6 CDJ52035.1 - 1.5 8.8 12.4 1.8 8.5 12.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 rve PF00665.26 CDJ52036.1 - 4.1e-14 52.8 0.0 1.1e-13 51.4 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ52036.1 - 2.7e-12 46.6 1.9 2.7e-12 46.6 1.9 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDJ52036.1 - 4e-05 23.7 1.4 8.5e-05 22.7 1.4 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDJ52036.1 - 0.0034 17.1 0.4 2 8.3 0.0 2.8 3 0 0 3 3 3 2 Integrase core domain RVP_2 PF08284.11 CDJ52037.1 - 3.6e-07 30.0 0.0 6.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ52037.1 - 8.3e-06 26.4 0.0 1.6e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ52037.1 - 1.3e-05 25.6 0.0 5e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ52037.1 - 0.022 15.1 0.0 0.099 13.0 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease Med15 PF09606.10 CDJ52038.1 - 3.5 6.2 27.7 6.1 5.4 27.7 1.3 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CDJ52038.1 - 4.7 6.0 15.0 1.8 7.4 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52038.1 - 10 5.7 24.7 1.7 8.2 5.2 2.1 2 0 0 2 2 2 0 Spt20 family RskA PF10099.9 CDJ52039.1 - 0.00099 19.5 7.1 0.00099 19.5 7.1 13.6 2 2 5 7 7 7 1 Anti-sigma-K factor rskA EIF4E-T PF10477.9 CDJ52039.1 - 0.022 13.6 0.0 0.022 13.6 0.0 5.7 1 1 5 6 6 6 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E SARAF PF06682.12 CDJ52039.1 - 0.099 12.3 0.0 0.099 12.3 0.0 8.6 3 2 2 6 6 6 0 SOCE-associated regulatory factor of calcium homoeostasis OTCace_N PF02729.21 CDJ52040.1 - 7e-36 123.5 0.3 2.7e-34 118.3 0.3 2.7 1 1 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 CDJ52040.1 - 5.8e-24 84.9 0.0 6.5e-23 81.5 0.0 2.6 3 0 0 3 3 3 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Pex26 PF07163.12 CDJ52040.1 - 0.0048 16.2 2.0 0.0048 16.2 2.0 2.8 2 1 1 3 3 3 1 Pex26 protein SR-25 PF10500.9 CDJ52040.1 - 0.0093 15.6 5.8 0.0093 15.6 5.8 2.6 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Med15 PF09606.10 CDJ52040.1 - 0.22 10.2 40.1 0.25 10.0 11.8 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal D123 PF07065.14 CDJ52040.1 - 1.2 8.2 7.5 0.069 12.3 1.3 2.0 3 0 0 3 3 3 0 D123 RLL PF10036.9 CDJ52040.1 - 1.5 8.6 22.4 1.1 9.1 8.8 2.4 1 1 0 2 2 2 0 RNA transcription, translation and transport factor protein Secretin_N_2 PF07655.13 CDJ52040.1 - 1.6 9.3 13.1 5.9 7.5 3.2 2.9 3 0 0 3 3 3 0 Secretin N-terminal domain EPL1 PF10513.9 CDJ52040.1 - 9.2 6.6 20.2 0.32 11.4 2.5 2.5 2 1 0 2 2 2 0 Enhancer of polycomb-like Cyt-b5 PF00173.28 CDJ52041.1 - 7.4e-06 26.0 0.0 1.8e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SR-25 PF10500.9 CDJ52041.1 - 0.12 11.9 7.5 0.18 11.4 7.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIF_alpha PF05793.12 CDJ52041.1 - 2.5 6.6 4.5 3.3 6.2 4.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF755 PF05501.11 CDJ52041.1 - 6.1 7.1 10.3 11 6.3 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) V_ATPase_I PF01496.19 CDJ52042.1 - 0.027 12.4 13.4 0.03 12.2 13.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 CDJ52042.1 - 0.055 12.4 3.1 0.061 12.3 3.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 CDJ52042.1 - 0.095 12.8 8.7 0.11 12.6 8.7 1.2 1 0 0 1 1 1 0 DDHD domain AP-5_subunit_s1 PF15001.6 CDJ52042.1 - 0.1 12.6 11.6 0.13 12.2 11.6 1.1 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF4407 PF14362.6 CDJ52042.1 - 0.11 11.8 17.1 0.15 11.4 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BORG_CEP PF14957.6 CDJ52042.1 - 0.15 13.3 4.6 0.18 13.0 4.6 1.2 1 0 0 1 1 1 0 Cdc42 effector Zip PF02535.22 CDJ52042.1 - 0.16 11.1 2.8 0.18 11.0 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CLN3 PF02487.17 CDJ52042.1 - 0.25 10.4 5.9 0.28 10.2 5.9 1.1 1 0 0 1 1 1 0 CLN3 protein MRP-S31 PF15433.6 CDJ52042.1 - 0.29 10.8 13.7 0.36 10.5 13.7 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 BAF1_ABF1 PF04684.13 CDJ52042.1 - 0.3 10.1 11.2 0.35 9.9 11.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor OATP PF03137.20 CDJ52042.1 - 0.39 8.9 3.0 0.44 8.8 3.0 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SLC12 PF03522.15 CDJ52042.1 - 0.52 9.3 12.2 0.59 9.1 12.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 CDJ52042.1 - 0.54 9.0 6.4 0.52 9.1 6.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ52042.1 - 0.58 8.4 25.5 0.67 8.2 25.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PA26 PF04636.13 CDJ52042.1 - 0.68 8.8 9.2 0.77 8.6 9.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TAF4 PF05236.14 CDJ52042.1 - 0.7 9.6 17.8 0.83 9.4 17.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Hamartin PF04388.12 CDJ52042.1 - 0.81 8.3 11.1 0.91 8.1 11.1 1.0 1 0 0 1 1 1 0 Hamartin protein Peptidase_S64 PF08192.11 CDJ52042.1 - 1.1 7.7 9.1 1.2 7.5 9.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 Spore_coat_CotO PF14153.6 CDJ52042.1 - 1.2 9.1 19.3 1.5 8.7 19.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DDRGK PF09756.9 CDJ52042.1 - 1.3 8.6 21.7 1.6 8.3 21.7 1.1 1 0 0 1 1 1 0 DDRGK domain DUF4746 PF15928.5 CDJ52042.1 - 1.5 8.2 6.8 1.9 7.8 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paf1 PF03985.13 CDJ52042.1 - 1.5 7.7 17.5 1.9 7.4 17.5 1.1 1 0 0 1 1 1 0 Paf1 MAJIN PF15077.6 CDJ52042.1 - 1.7 8.3 10.3 2 8.1 10.3 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF572 PF04502.13 CDJ52042.1 - 1.7 8.2 15.1 2.1 7.9 15.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Med19 PF10278.9 CDJ52042.1 - 1.9 8.4 10.1 2.3 8.1 10.1 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 API5 PF05918.11 CDJ52042.1 - 2 7.1 14.6 2.3 6.9 14.6 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) NPR3 PF03666.13 CDJ52042.1 - 2.1 7.1 14.6 2.3 6.9 14.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PAP_RNA-bind PF04926.15 CDJ52042.1 - 2.1 7.9 9.8 7.9 6.1 9.8 1.8 1 1 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain TFIIA PF03153.13 CDJ52042.1 - 2.1 8.2 43.3 2.7 7.9 43.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMM1 PF10296.9 CDJ52042.1 - 2.6 7.0 8.0 3.3 6.7 8.0 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DUF2126 PF09899.9 CDJ52042.1 - 2.9 5.8 10.2 3.1 5.8 10.2 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Ebp2 PF05890.12 CDJ52042.1 - 2.9 7.4 21.6 3.6 7.0 21.6 1.1 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 DUF3292 PF11696.8 CDJ52042.1 - 3 6.1 9.8 3.4 5.9 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Presenilin PF01080.17 CDJ52042.1 - 3.4 6.3 19.9 3.9 6.2 19.9 1.0 1 0 0 1 1 1 0 Presenilin DUF4637 PF15470.6 CDJ52042.1 - 3.8 7.2 10.4 15 5.3 10.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) Neur_chan_memb PF02932.16 CDJ52042.1 - 3.9 7.5 13.0 4.7 7.2 13.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.12 CDJ52042.1 - 4.3 6.6 22.3 6.3 6.1 22.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NARP1 PF12569.8 CDJ52042.1 - 4.8 6.0 14.4 5.5 5.8 14.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SART-1 PF03343.13 CDJ52042.1 - 5.1 5.5 21.4 5.8 5.3 21.4 1.0 1 0 0 1 1 1 0 SART-1 family Serinc PF03348.15 CDJ52042.1 - 5.2 5.9 6.3 5.5 5.8 6.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM60A PF15396.6 CDJ52042.1 - 5.4 6.9 10.7 6.6 6.7 10.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A eIF-3_zeta PF05091.12 CDJ52042.1 - 6.2 5.7 23.7 8.3 5.3 23.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 CDJ52042.1 - 6.4 6.5 17.0 7.7 6.3 17.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hydin_ADK PF17213.3 CDJ52042.1 - 6.7 6.9 12.9 9.1 6.5 12.9 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain YABBY PF04690.13 CDJ52042.1 - 7.6 7.1 10.9 10 6.6 10.9 1.3 1 0 0 1 1 1 0 YABBY protein DUF1822 PF08852.11 CDJ52042.1 - 7.8 5.4 23.0 9.6 5.1 23.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) CCDC53 PF10152.9 CDJ52042.1 - 7.9 6.9 18.2 11 6.4 18.2 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2227 PF09988.9 CDJ52042.1 - 8.2 6.3 6.5 14 5.5 6.5 1.6 1 1 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) Gti1_Pac2 PF09729.9 CDJ52042.1 - 8.9 6.4 12.0 12 5.9 12.0 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family CDC45 PF02724.14 CDJ52042.1 - 9.5 4.4 13.3 11 4.2 13.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Membralin PF09746.9 CDJ52042.1 - 9.6 5.1 7.7 11 4.9 7.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein DnaJ PF00226.31 CDJ52043.1 - 4.8e-13 49.0 0.0 1.5e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 DnaJ domain Tim54 PF11711.8 CDJ52043.1 - 0.064 12.0 30.4 0.16 10.7 17.1 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 CDJ52043.1 - 0.1 12.4 46.7 0.089 12.6 25.2 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4471 PF14740.6 CDJ52043.1 - 0.71 9.0 27.8 0.1 11.8 13.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) CCSAP PF15748.5 CDJ52043.1 - 0.74 9.9 54.6 0.28 11.3 31.1 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF4045 PF13254.6 CDJ52043.1 - 0.75 9.4 40.1 0.48 10.0 5.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) FAM76 PF16046.5 CDJ52043.1 - 8.9 5.6 50.0 1.5 8.1 28.9 2.1 2 0 0 2 2 2 0 FAM76 protein PP2C PF00481.21 CDJ52044.1 - 1.9e-33 116.2 0.0 3e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ52044.1 - 0.0029 17.5 0.0 0.0037 17.2 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) EMG1 PF03587.14 CDJ52045.1 - 4.3e-14 52.6 0.2 0.00071 19.3 0.0 3.9 3 1 0 3 3 3 3 EMG1/NEP1 methyltransferase DUF4407 PF14362.6 CDJ52045.1 - 0.9 8.8 57.7 0.0064 15.9 19.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) TFIIF_alpha PF05793.12 CDJ52046.1 - 0.076 11.6 36.2 0.11 11.0 36.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SR-25 PF10500.9 CDJ52046.1 - 3.8 7.0 46.0 9.4 5.8 46.0 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 CDJ52046.1 - 7.9 5.9 50.3 9.2 5.7 50.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Caldesmon PF02029.15 CDJ52047.1 - 0.85 8.3 25.1 1.2 7.9 25.1 1.1 1 0 0 1 1 1 0 Caldesmon DUF572 PF04502.13 CDJ52047.1 - 0.86 9.2 25.2 0.78 9.3 6.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Atg14 PF10186.9 CDJ52047.1 - 2.4 7.2 20.6 4 6.4 20.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SARAF PF06682.12 CDJ52047.1 - 3.5 7.2 34.9 7.6 6.1 34.7 1.7 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis VIR_N PF15912.5 CDJ52047.1 - 8.3 5.9 12.6 0.99 8.9 2.0 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal UCH PF00443.29 CDJ52048.1 - 0.34 10.4 11.2 0.55 9.7 11.2 1.5 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF4512 PF14975.6 CDJ52048.1 - 0.44 11.4 0.1 0.44 11.4 0.1 4.0 3 2 0 3 3 3 0 Domain of unknown function (DUF4512) DUF2339 PF10101.9 CDJ52049.1 - 1 7.9 9.7 1.4 7.4 9.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) SARAF PF06682.12 CDJ52049.1 - 1.6 8.3 45.7 0.45 10.1 29.8 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2057 PF09829.9 CDJ52050.1 - 3.3 7.8 17.2 0.054 13.7 1.8 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2057) TFIIA PF03153.13 CDJ52051.1 - 0.0017 18.5 18.8 0.0017 18.5 18.8 2.1 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 CDJ52051.1 - 0.21 11.2 6.4 0.36 10.4 6.4 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3801 PF12687.7 CDJ52051.1 - 0.46 10.5 9.3 0.036 14.1 4.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) DUF1980 PF09323.10 CDJ52051.1 - 0.47 10.3 1.5 0.85 9.5 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PAT1 PF09770.9 CDJ52051.1 - 1.1 7.4 17.2 1.7 6.8 17.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FHIPEP PF00771.20 CDJ52051.1 - 1.6 7.1 4.2 3.2 6.1 4.2 1.4 1 0 0 1 1 1 0 FHIPEP family Hydin_ADK PF17213.3 CDJ52051.1 - 2.2 8.5 7.0 5.5 7.2 7.0 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Lin-8 PF03353.15 CDJ52051.1 - 3.8 7.0 11.6 6.5 6.2 11.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Endostatin PF06482.11 CDJ52051.1 - 6.9 6.0 11.2 11 5.4 11.2 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin MMR_HSR1_C PF08438.10 CDJ52052.1 - 2.6e-24 85.9 0.0 1.5e-23 83.5 0.0 2.1 2 1 0 2 2 2 1 GTPase of unknown function C-terminal HMGL-like PF00682.19 CDJ52052.1 - 0.046 13.3 0.1 0.067 12.7 0.1 1.2 1 0 0 1 1 1 0 HMGL-like ATP_bind_1 PF03029.17 CDJ52052.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF3138 PF11336.8 CDJ52052.1 - 5.1 5.6 6.0 6.2 5.3 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spt20 PF12090.8 CDJ52053.1 - 0.0017 18.0 11.7 0.0017 18.0 11.7 1.1 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ52053.1 - 0.0032 17.5 10.7 0.0036 17.4 10.7 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ52053.1 - 0.0033 16.5 8.8 0.0035 16.4 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4770 PF15994.5 CDJ52053.1 - 0.0066 16.7 1.9 0.0071 16.6 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) Med15 PF09606.10 CDJ52053.1 - 0.0074 15.0 8.0 0.0067 15.2 8.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal EIF4E-T PF10477.9 CDJ52053.1 - 0.019 13.8 5.8 0.022 13.6 5.8 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E MAGE PF01454.19 CDJ52053.1 - 0.027 14.2 0.7 0.029 14.1 0.7 1.0 1 0 0 1 1 1 0 MAGE family PCYCGC PF13798.6 CDJ52053.1 - 0.054 13.3 0.8 0.07 13.0 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif Tim54 PF11711.8 CDJ52053.1 - 0.055 12.3 1.5 0.058 12.2 1.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Gaa1 PF04114.14 CDJ52053.1 - 0.076 12.0 0.3 0.078 12.0 0.3 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Roughex PF06020.11 CDJ52053.1 - 0.083 12.0 5.6 0.086 11.9 5.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Suf PF05843.14 CDJ52053.1 - 0.17 11.8 4.9 0.18 11.7 4.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.8 CDJ52053.1 - 0.9 8.4 21.4 1.2 8.0 21.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PepSY_TM PF03929.16 CDJ52054.1 - 0.054 13.2 0.0 0.49 10.0 0.0 1.9 1 1 0 1 1 1 0 PepSY-associated TM region Androgen_recep PF02166.16 CDJ52054.1 - 0.064 12.1 2.9 0.071 11.9 2.9 1.1 1 0 0 1 1 1 0 Androgen receptor RIC3 PF15361.6 CDJ52054.1 - 0.071 13.5 0.8 0.12 12.8 0.8 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 SelP_N PF04592.14 CDJ52054.1 - 0.23 10.8 9.6 0.33 10.3 9.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pex14_N PF04695.13 CDJ52055.1 - 0.0054 17.4 0.6 0.011 16.4 0.0 1.8 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.11 CDJ52055.1 - 8.4 4.3 13.1 10 4.0 13.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_60s PF00428.19 CDJ52056.1 - 0.034 14.7 2.7 0.034 14.7 2.7 4.9 4 0 0 4 4 4 0 60s Acidic ribosomal protein HTH_9 PF08221.11 CDJ52056.1 - 0.57 10.3 4.4 5.2 7.2 0.0 2.8 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain zf-ZPR1 PF03367.13 CDJ52057.1 - 5.3e-20 71.9 0.0 5.3e-20 71.9 0.0 3.9 3 1 1 4 4 4 2 ZPR1 zinc-finger domain Mu-like_Com PF10122.9 CDJ52057.1 - 0.0096 15.4 1.0 2.2 7.8 0.0 2.8 3 0 0 3 3 3 2 Mu-like prophage protein Com zf-tcix PF14952.6 CDJ52057.1 - 0.013 15.1 0.3 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding RskA PF10099.9 CDJ52057.1 - 0.026 14.8 0.9 0.026 14.8 0.9 3.5 1 1 2 3 3 3 0 Anti-sigma-K factor rskA LIM_bind PF01803.16 CDJ52057.1 - 9 5.7 24.0 0.71 9.4 6.9 2.5 2 0 0 2 2 2 0 LIM-domain binding protein DUF2203 PF09969.9 CDJ52058.1 - 0.038 14.7 1.4 0.062 14.0 1.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) AAR2 PF05282.11 CDJ52058.1 - 0.043 13.2 0.1 0.056 12.9 0.1 1.1 1 0 0 1 1 1 0 AAR2 protein DUF4695 PF15766.5 CDJ52058.1 - 0.05 13.8 1.1 0.073 13.3 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) HD_assoc PF13286.6 CDJ52058.1 - 0.052 14.1 0.4 0.15 12.6 0.2 1.7 1 1 0 1 1 1 0 Phosphohydrolase-associated domain AAA_23 PF13476.6 CDJ52058.1 - 0.1 13.1 0.3 0.13 12.8 0.3 1.1 1 0 0 1 1 1 0 AAA domain FUSC-like PF12805.7 CDJ52058.1 - 0.12 11.5 0.3 0.16 11.0 0.3 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS YabA PF06156.13 CDJ52058.1 - 0.15 12.7 0.6 0.24 12.1 0.6 1.3 1 0 0 1 1 1 0 Initiation control protein YabA SlyX PF04102.12 CDJ52058.1 - 0.43 11.2 3.9 6.3 7.5 1.1 2.4 1 1 1 2 2 2 0 SlyX Pkinase PF00069.25 CDJ52059.1 - 0.1 11.9 0.0 0.1 11.9 0.0 2.2 3 0 0 3 3 3 0 Protein kinase domain DUF4778 PF16008.5 CDJ52059.1 - 0.21 11.6 13.1 0.28 11.2 6.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) Suf PF05843.14 CDJ52059.1 - 0.25 11.3 30.5 0.21 11.6 11.5 3.3 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) PRP1_N PF06424.12 CDJ52059.1 - 0.34 11.3 19.3 0.37 11.2 8.4 2.7 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Sin_N PF04801.13 CDJ52059.1 - 0.94 8.6 39.0 0.1 11.8 10.5 2.7 2 1 0 2 2 2 0 Sin-like protein conserved region ALMT PF11744.8 CDJ52059.1 - 2.3 7.0 14.5 1 8.1 1.4 2.4 2 0 0 2 2 2 0 Aluminium activated malate transporter Exo5 PF09810.9 CDJ52060.1 - 4.3e-25 89.0 0.3 4.3e-25 89.0 0.3 4.8 4 1 0 4 4 4 1 Exonuclease V - a 5' deoxyribonuclease DUF2722 PF10846.8 CDJ52060.1 - 0.0027 16.7 20.5 0.0027 16.7 20.5 6.5 4 1 2 6 6 6 3 Protein of unknown function (DUF2722) Succ_DH_flav_C PF02910.20 CDJ52061.1 - 6.5e-29 100.5 3.5 7.4e-29 100.3 3.5 1.1 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term NPR3 PF03666.13 CDJ52062.1 - 0.68 8.7 26.4 0.73 8.6 26.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 CDJ52062.1 - 0.86 8.7 22.5 1 8.5 22.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 CDJ52062.1 - 1.1 9.0 32.4 1.2 8.9 32.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ52062.1 - 1.2 9.1 24.8 1.4 8.9 24.8 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Membralin PF09746.9 CDJ52062.1 - 2.1 7.3 17.6 2.2 7.2 17.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein Cyto_heme_lyase PF01265.17 CDJ52062.1 - 3 7.3 20.9 3.1 7.3 20.9 1.0 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase DUF5427 PF10310.9 CDJ52062.1 - 3.6 6.5 28.0 4 6.3 28.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4050 PF13259.6 CDJ52062.1 - 5.2 7.4 24.1 6.8 7.0 24.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF2370 PF10176.9 CDJ52062.1 - 5.9 6.5 14.1 7.4 6.1 14.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) XAP5 PF04921.14 CDJ52062.1 - 6.4 6.5 26.7 7.3 6.3 26.7 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator Plasmodium_Vir PF05795.11 CDJ52062.1 - 8.3 5.7 14.6 11 5.3 14.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF913 PF06025.12 CDJ52062.1 - 8.5 5.2 16.8 11 4.9 16.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Raftlin PF15250.6 CDJ52062.1 - 9 4.9 22.2 9.7 4.8 22.2 1.0 1 0 0 1 1 1 0 Raftlin DUF3449 PF11931.8 CDJ52063.1 - 2.3e-70 236.1 4.3 2.3e-59 200.3 0.3 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3449) DUF2956 PF11169.8 CDJ52063.1 - 0.013 15.6 0.0 0.036 14.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Desulfoferrod_N PF06397.12 CDJ52063.1 - 0.061 13.0 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Pol_alpha_B_N PF08418.10 CDJ52064.1 - 0.76 9.7 5.4 0.98 9.3 5.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Rtf2 PF04641.12 CDJ52064.1 - 1.3 8.3 4.2 1.3 8.3 4.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger FGF-BP1 PF06473.12 CDJ52064.1 - 6.9 6.4 6.7 13 5.5 6.7 1.6 1 1 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) ANAPC_CDC26 PF10471.9 CDJ52065.1 - 0.0028 18.5 11.2 0.0028 18.5 11.2 3.5 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CDJ52065.1 - 0.018 14.6 14.6 0.018 14.6 14.6 2.0 2 1 0 2 2 2 0 Spt20 family DUF755 PF05501.11 CDJ52065.1 - 0.56 10.5 25.5 0.31 11.3 5.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF2407 PF10302.9 CDJ52065.1 - 0.94 10.1 5.8 0.097 13.2 1.1 1.8 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain Ribosomal_S2 PF00318.20 CDJ52066.1 - 1.1e-28 100.0 1.7 2.6e-14 53.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CDJ52066.1 - 1.9 9.9 29.3 3.3 9.1 26.3 3.0 2 1 0 2 2 2 0 40S ribosomal protein SA C-terminus Apc15p PF05841.11 CDJ52067.1 - 1.2 10.0 32.7 4.9 8.0 6.5 2.5 2 0 0 2 2 2 0 Apc15p protein PAT1 PF09770.9 CDJ52067.1 - 1.3 7.2 45.4 1.7 6.8 45.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MMU163 PF17119.5 CDJ52067.1 - 2.7 7.1 22.4 1.3 8.1 5.3 2.3 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis DUF4614 PF15391.6 CDJ52067.1 - 8.3 6.4 28.9 2.2 8.2 13.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) RskA PF10099.9 CDJ52068.1 - 0.92 9.8 25.7 34 4.7 25.7 2.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA CDC45 PF02724.14 CDJ52068.1 - 4.1 5.6 37.5 6.6 4.9 37.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Helicase_C PF00271.31 CDJ52069.1 - 1.9e-32 111.9 0.0 2.7e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CDJ52069.1 - 0.04 13.1 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF72 PF01904.18 CDJ52069.1 - 0.048 13.8 0.1 0.059 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF72 RskA PF10099.9 CDJ52070.1 - 3.1e-06 27.6 42.9 0.015 15.6 0.0 3.5 1 1 2 3 3 3 2 Anti-sigma-K factor rskA DUF3682 PF12446.8 CDJ52070.1 - 0.00025 21.5 22.4 0.00025 21.5 22.4 4.3 2 1 2 4 4 4 1 Protein of unknown function (DUF3682) DUF4179 PF13786.6 CDJ52070.1 - 0.1 13.1 0.2 0.1 13.1 0.2 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) SID-1_RNA_chan PF13965.6 CDJ52070.1 - 0.6 8.4 3.5 1.4 7.3 0.7 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Trp_oprn_chp PF09534.10 CDJ52070.1 - 2.5 7.9 36.9 0.78 9.5 5.8 2.9 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SR-25 PF10500.9 CDJ52071.1 - 0.0034 17.0 13.4 0.0034 17.0 13.4 5.4 3 2 0 4 4 4 1 Nuclear RNA-splicing-associated protein C_GCAxxG_C_C PF09719.10 CDJ52071.1 - 0.015 15.6 1.5 0.015 15.6 1.5 2.9 3 1 0 3 3 3 0 Putative redox-active protein (C_GCAxxG_C_C) Kinase-like PF14531.6 CDJ52073.1 - 1.3e-09 37.8 0.0 8.9e-09 35.1 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 CDJ52073.1 - 9.1e-06 25.2 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ52073.1 - 0.089 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase RIFIN PF02009.16 CDJ52075.1 - 5 6.9 18.9 6.3 6.6 18.9 1.1 1 0 0 1 1 1 0 Rifin tRNA-synt_1 PF00133.22 CDJ52076.1 - 1.4e-20 73.1 6.6 2.2e-15 56.0 0.0 9.4 8 1 0 9 9 9 5 tRNA synthetases class I (I, L, M and V) NAM-associated PF14303.6 CDJ52076.1 - 1.7e-09 38.7 0.0 0.00067 20.4 0.0 19.8 12 5 1 13 13 13 2 No apical meristem-associated C-terminal domain Pex26 PF07163.12 CDJ52076.1 - 0.00039 19.8 4.4 0.00039 19.8 4.4 25.2 13 9 9 24 24 24 1 Pex26 protein SPX PF03105.19 CDJ52076.1 - 0.001 19.1 29.9 0.001 19.1 29.9 14.3 5 4 4 9 9 9 1 SPX domain BUD22 PF09073.10 CDJ52076.1 - 0.0029 17.0 7.3 0.0029 17.0 7.3 11.6 5 2 2 10 10 10 5 BUD22 GAGA_bind PF06217.12 CDJ52076.1 - 0.0038 17.6 10.5 0.0038 17.6 10.5 15.1 9 4 3 13 13 13 1 GAGA binding protein-like family Macoilin PF09726.9 CDJ52078.1 - 0.00061 18.5 20.4 0.0011 17.7 20.4 1.3 1 0 0 1 1 1 1 Macoilin family Band_3_cyto PF07565.13 CDJ52078.1 - 0.0086 15.9 8.2 0.0086 15.9 8.2 2.1 2 0 0 2 2 2 1 Band 3 cytoplasmic domain LMBR1 PF04791.16 CDJ52078.1 - 0.011 14.7 1.8 0.012 14.5 1.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 CDJ52078.1 - 0.11 12.0 12.1 0.23 11.0 12.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit eIF-3_zeta PF05091.12 CDJ52078.1 - 0.14 11.1 16.8 0.2 10.6 16.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Apt1 PF10351.9 CDJ52078.1 - 0.19 10.6 21.8 0.87 8.4 3.6 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain RskA PF10099.9 CDJ52078.1 - 0.47 10.7 26.9 75 3.6 26.9 3.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Serinc PF03348.15 CDJ52078.1 - 0.57 9.0 7.0 0.96 8.3 7.0 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) RIFIN PF02009.16 CDJ52078.1 - 0.58 10.0 10.6 1.4 8.8 10.6 1.5 1 0 0 1 1 1 0 Rifin Hamartin PF04388.12 CDJ52078.1 - 1.4 7.5 34.7 2.2 6.8 34.7 1.3 1 0 0 1 1 1 0 Hamartin protein DUF572 PF04502.13 CDJ52078.1 - 1.5 8.4 19.5 0.64 9.6 8.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4746 PF15928.5 CDJ52078.1 - 1.6 8.1 9.5 2.6 7.4 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Peptidase_S49_N PF08496.10 CDJ52078.1 - 2.6 8.1 16.4 4.7 7.3 16.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Endostatin PF06482.11 CDJ52078.1 - 9 5.7 20.6 0.56 9.6 12.5 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Evr1_Alr PF04777.13 CDJ52079.1 - 0.0021 18.5 0.0 0.0062 17.0 0.0 1.7 1 0 0 1 1 1 1 Erv1 / Alr family Calici_coat PF00915.20 CDJ52079.1 - 1.4 7.8 5.4 1.8 7.4 5.4 1.2 1 0 0 1 1 1 0 Calicivirus coat protein DUF1180 PF06679.12 CDJ52079.1 - 5.1 7.5 10.7 6.3 7.2 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RNA_pol_Rpc4 PF05132.14 CDJ52079.1 - 6.1 7.3 6.5 9.7 6.6 6.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 TraT PF05818.12 CDJ52079.1 - 6.9 6.3 9.9 8.7 6.0 9.9 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Dehydrin PF00257.19 CDJ52080.1 - 2 8.9 8.3 3.1 8.3 8.3 1.2 1 0 0 1 1 1 0 Dehydrin SH3BP5 PF05276.14 CDJ52081.1 - 0.072 12.9 0.3 0.11 12.3 0.3 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) COPI_assoc PF08507.10 CDJ52084.1 - 1.3e-09 38.2 1.8 1.6e-09 37.9 1.8 1.1 1 0 0 1 1 1 1 COPI associated protein TMEM72 PF16054.5 CDJ52084.1 - 4.9 6.8 5.7 2.7 7.6 2.9 1.8 1 1 1 2 2 2 0 Transmembrane protein family 72 G-patch PF01585.23 CDJ52086.1 - 1.2e-14 53.8 1.1 2.1e-14 53.1 1.1 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ52086.1 - 0.00036 20.6 0.4 0.0011 19.0 0.4 1.8 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 CDJ52086.1 - 0.001 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBP4 PF07960.11 CDJ52086.1 - 0.098 12.5 0.3 0.098 12.5 0.3 1.7 2 0 0 2 2 2 0 CBP4 AAA_12 PF13087.6 CDJ52087.1 - 7.9e-53 179.0 0.0 1.1e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ52087.1 - 3e-45 155.1 0.1 6.3e-27 95.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 CDJ52087.1 - 7.2e-12 45.4 0.0 3.7e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ52087.1 - 2.4e-10 40.9 0.0 1.7e-09 38.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain PIF1 PF05970.14 CDJ52087.1 - 1.2e-05 24.7 0.0 0.0025 17.0 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DUF2075 PF09848.9 CDJ52087.1 - 9e-05 21.9 0.2 0.024 13.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CDJ52087.1 - 0.00049 20.1 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.16 CDJ52087.1 - 0.0005 19.6 0.0 0.0061 16.0 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 CDJ52087.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CDJ52087.1 - 0.0013 18.5 0.0 0.68 9.6 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 CDJ52087.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 CDJ52087.1 - 0.018 15.5 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ52087.1 - 0.022 14.5 0.0 0.069 12.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain UvrD-helicase PF00580.21 CDJ52087.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 CDJ52087.1 - 0.043 13.6 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 CDJ52087.1 - 0.045 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 CDJ52087.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.6 CDJ52087.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain dsrm PF00035.26 CDJ52088.1 - 0.001 19.8 0.2 0.61 10.8 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DSPc PF00782.20 CDJ52089.1 - 2.7e-20 72.5 0.0 4.6e-17 62.1 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ52089.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase eIF3_p135 PF12807.7 CDJ52090.1 - 0.00023 21.3 0.0 0.00093 19.3 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 MORN PF02493.20 CDJ52091.1 - 9.1e-23 78.7 30.8 0.00026 20.7 0.0 9.0 9 0 0 9 9 9 6 MORN repeat Avl9 PF09794.9 CDJ52091.1 - 3.8e-22 78.5 0.0 2.5e-19 69.3 0.0 2.4 1 1 0 1 1 1 1 Transport protein Avl9 DENN PF02141.21 CDJ52091.1 - 0.0012 18.9 0.8 0.0025 17.8 0.3 1.7 2 0 0 2 2 2 1 DENN (AEX-3) domain Choline_transpo PF04515.12 CDJ52092.1 - 1e-31 110.3 31.1 3.1e-29 102.2 5.9 3.5 3 1 1 4 4 4 2 Plasma-membrane choline transporter HSP70 PF00012.20 CDJ52093.1 - 3.3e-83 279.9 15.1 7.9e-46 156.4 0.0 4.7 2 1 1 5 5 4 3 Hsp70 protein Suf PF05843.14 CDJ52093.1 - 0.013 15.5 1.4 0.013 15.5 1.4 2.6 3 0 0 3 3 2 0 Suppressor of forked protein (Suf) DUF4667 PF15700.5 CDJ52093.1 - 0.018 15.2 1.8 2.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) DUF1764 PF08576.10 CDJ52093.1 - 0.018 16.0 10.8 0.042 14.7 1.1 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RXT2_N PF08595.11 CDJ52093.1 - 0.039 14.0 4.7 0.47 10.5 0.7 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Eapp_C PF10238.9 CDJ52093.1 - 0.066 13.3 8.3 0.68 10.0 0.5 2.7 2 0 0 2 2 2 0 E2F-associated phosphoprotein SpoIIP PF07454.11 CDJ52093.1 - 0.092 12.2 9.1 1.4 8.3 1.9 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Rxt3 PF08642.10 CDJ52093.1 - 0.11 13.2 2.0 9.9 7.0 0.2 2.6 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 MreB_Mbl PF06723.13 CDJ52093.1 - 0.11 11.2 1.2 5.6 5.7 0.1 3.0 3 0 0 3 3 3 0 MreB/Mbl protein Velvet PF11754.8 CDJ52093.1 - 0.14 12.1 5.9 2.6 7.9 0.6 2.3 2 0 0 2 2 2 0 Velvet factor Presenilin PF01080.17 CDJ52093.1 - 0.19 10.5 15.3 0.28 9.9 4.5 2.1 2 0 0 2 2 2 0 Presenilin FAM163 PF15069.6 CDJ52093.1 - 0.32 11.4 4.8 0.81 10.1 0.2 2.6 2 0 0 2 2 2 0 FAM163 family MAM33 PF02330.16 CDJ52093.1 - 0.45 10.4 12.4 1.9 8.4 2.1 2.3 2 0 0 2 2 2 0 Mitochondrial glycoprotein RskA PF10099.9 CDJ52093.1 - 0.5 10.6 32.9 1.5 9.1 0.3 4.2 3 1 0 3 3 3 0 Anti-sigma-K factor rskA FAM176 PF14851.6 CDJ52093.1 - 0.55 9.9 7.6 5.1 6.7 1.0 2.4 2 0 0 2 2 2 0 FAM176 family MecA PF05389.12 CDJ52093.1 - 0.88 9.2 7.8 1.4 8.5 0.3 2.4 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Thg1C PF14413.6 CDJ52093.1 - 1.2 9.3 6.8 8.4 6.6 1.6 2.5 2 0 0 2 2 2 0 Thg1 C terminal domain V_ATPase_I PF01496.19 CDJ52093.1 - 1.3 6.8 8.5 2.8 5.7 0.8 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4471 PF14740.6 CDJ52093.1 - 1.6 7.8 6.6 7.6 5.7 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) DUF3381 PF11861.8 CDJ52093.1 - 2.2 8.1 16.4 5.1 6.9 2.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) LIM_bind PF01803.16 CDJ52093.1 - 3 7.3 12.0 1.2 8.7 2.1 2.4 2 0 0 2 2 2 0 LIM-domain binding protein DUF1980 PF09323.10 CDJ52093.1 - 3.2 7.6 6.0 17 5.2 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CPSF100_C PF13299.6 CDJ52093.1 - 3.4 7.8 14.8 3 8.0 0.3 2.7 3 0 0 3 3 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4050 PF13259.6 CDJ52093.1 - 3.5 7.9 10.4 3.5 7.9 0.5 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF4050) DUF4746 PF15928.5 CDJ52093.1 - 3.5 7.0 10.9 4.8 6.5 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Sld5 PF05916.11 CDJ52093.1 - 3.8 8.0 6.3 0.68 10.4 0.1 2.8 3 0 0 3 3 2 0 GINS complex protein DUF719 PF05334.13 CDJ52093.1 - 4 7.6 15.3 2.4 8.3 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF719) TRAP_alpha PF03896.16 CDJ52093.1 - 4.4 6.4 7.6 5.9 6.0 2.4 2.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit RPA43_OB PF17875.1 CDJ52093.1 - 4.5 7.9 9.4 15 6.3 1.1 2.6 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I F-protein PF00469.20 CDJ52093.1 - 5.6 6.5 7.6 5.2 6.6 0.7 2.4 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef S36_mt PF10937.8 CDJ52093.1 - 5.8 8.5 17.9 2.7 9.6 4.8 3.3 4 0 0 4 4 2 0 Ribosomal protein S36, mitochondrial DUF913 PF06025.12 CDJ52093.1 - 6 5.7 7.3 19 4.1 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 CDJ52093.1 - 6.5 7.2 15.3 5.4 7.4 5.0 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Band_3_cyto PF07565.13 CDJ52093.1 - 6.6 6.5 13.2 2.5 7.8 0.8 3.1 3 0 0 3 3 3 0 Band 3 cytoplasmic domain TEX19 PF15553.6 CDJ52093.1 - 6.8 6.6 9.8 6.9 6.6 3.5 2.5 2 0 0 2 2 2 0 Testis-expressed protein 19 Myco_haema PF05692.12 CDJ52093.1 - 7.3 5.4 9.1 6.4 5.6 2.7 2.2 2 0 0 2 2 2 0 Mycoplasma haemagglutinin EIIBC-GUT_N PF03612.14 CDJ52093.1 - 8.5 6.1 13.5 1.1 9.0 1.2 2.8 3 0 0 3 3 2 0 Sorbitol phosphotransferase enzyme II N-terminus TCP PF03634.13 CDJ52093.1 - 9.6 6.7 12.3 4.8 7.7 0.6 2.5 2 0 0 2 2 2 0 TCP family transcription factor Sporozoite_P67 PF05642.11 CDJ52097.1 - 0.065 11.3 42.1 0.1 10.7 42.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SR-25 PF10500.9 CDJ52098.1 - 0.0061 16.2 37.4 0.0061 16.2 37.4 3.0 2 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein DoxX_3 PF13781.6 CDJ52098.1 - 0.031 14.9 0.1 0.055 14.1 0.1 1.4 1 0 0 1 1 1 0 DoxX-like family DUF1645 PF07816.11 CDJ52099.1 - 9.1e-05 23.1 12.1 0.00011 22.9 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ52099.1 - 0.0049 16.5 20.9 0.0065 16.1 20.9 1.3 1 0 0 1 1 1 1 Spt20 family TFB6 PF17110.5 CDJ52099.1 - 0.02 14.7 0.6 0.022 14.5 0.6 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TFIIA PF03153.13 CDJ52099.1 - 0.025 14.6 20.4 0.028 14.4 20.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3295 PF11702.8 CDJ52099.1 - 0.042 13.2 19.4 0.046 13.1 19.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) EIIBC-GUT_N PF03612.14 CDJ52099.1 - 0.048 13.4 2.7 0.077 12.7 2.7 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Totivirus_coat PF05518.11 CDJ52099.1 - 0.08 11.0 2.8 0.08 11.0 2.8 1.0 1 0 0 1 1 1 0 Totivirus coat protein Lin-8 PF03353.15 CDJ52099.1 - 0.13 11.8 14.2 0.15 11.6 14.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AF-4 PF05110.13 CDJ52099.1 - 0.14 10.2 27.3 0.16 10.0 27.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AAA_24 PF13479.6 CDJ52099.1 - 0.2 11.3 1.0 0.27 10.9 1.0 1.1 1 0 0 1 1 1 0 AAA domain DUF276 PF03434.13 CDJ52099.1 - 0.2 10.8 0.6 0.29 10.2 0.6 1.2 1 0 0 1 1 1 0 DUF276 Macoilin PF09726.9 CDJ52099.1 - 0.23 10.0 15.9 0.26 9.8 15.9 1.0 1 0 0 1 1 1 0 Macoilin family CLN3 PF02487.17 CDJ52099.1 - 0.25 10.3 4.3 0.3 10.1 4.3 1.1 1 0 0 1 1 1 0 CLN3 protein DUF913 PF06025.12 CDJ52099.1 - 0.29 10.1 6.4 0.36 9.8 6.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) WES_acyltransf PF03007.16 CDJ52099.1 - 0.43 10.3 2.7 0.62 9.8 2.7 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain GREB1 PF15782.5 CDJ52099.1 - 0.45 7.6 19.0 0.52 7.4 19.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Herpes_DNAp_acc PF04929.12 CDJ52099.1 - 0.56 9.1 13.3 0.63 9.0 13.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CDK2AP PF09806.9 CDJ52099.1 - 0.64 10.1 14.1 0.8 9.7 14.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Miga PF10265.9 CDJ52099.1 - 0.66 8.9 12.5 0.73 8.7 12.5 1.0 1 0 0 1 1 1 0 Mitoguardin DUF4175 PF13779.6 CDJ52099.1 - 0.76 7.6 15.6 0.85 7.5 15.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SLC12 PF03522.15 CDJ52099.1 - 0.98 8.4 9.5 1 8.3 9.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Plasmodium_Vir PF05795.11 CDJ52099.1 - 0.98 8.8 10.1 1.1 8.5 10.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Roughex PF06020.11 CDJ52099.1 - 1.1 8.3 10.3 1.3 8.1 10.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Apt1 PF10351.9 CDJ52099.1 - 1.5 7.6 16.7 1.7 7.4 16.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ52099.1 - 1.8 7.2 14.9 2.1 7.1 14.9 1.0 1 0 0 1 1 1 0 Presenilin Kei1 PF08552.11 CDJ52099.1 - 2.1 8.2 5.6 2.9 7.7 5.6 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Sporozoite_P67 PF05642.11 CDJ52099.1 - 2.3 6.2 14.4 2.7 6.0 14.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med24_N PF11277.8 CDJ52099.1 - 2.6 6.0 10.4 3 5.8 10.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Membralin PF09746.9 CDJ52099.1 - 2.9 6.8 7.5 3.2 6.7 7.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein ALMT PF11744.8 CDJ52099.1 - 3.5 6.3 10.2 4 6.2 10.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Dicty_REP PF05086.12 CDJ52099.1 - 5 5.0 9.2 5.5 4.8 9.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CobT PF06213.12 CDJ52099.1 - 5.4 6.3 13.8 7 5.9 13.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peptidase_S64 PF08192.11 CDJ52099.1 - 5.9 5.2 18.1 6.4 5.1 18.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 Menin PF05053.13 CDJ52099.1 - 6.9 4.9 10.4 7.6 4.8 10.4 1.0 1 0 0 1 1 1 0 Menin RRM_1 PF00076.22 CDJ52100.1 - 1.3e-28 98.6 0.0 0.0001 22.1 0.0 6.8 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_8 PF13855.6 CDJ52100.1 - 1.4e-06 28.0 22.8 0.00043 20.0 7.2 4.5 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CDJ52100.1 - 2.2e-05 24.7 28.5 0.00043 20.6 4.0 4.8 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) DUF3682 PF12446.8 CDJ52100.1 - 0.0001 22.8 11.3 0.0001 22.8 11.3 13.9 13 3 0 13 13 13 2 Protein of unknown function (DUF3682) LRR_9 PF14580.6 CDJ52100.1 - 0.0004 19.9 5.2 0.01 15.4 0.1 3.0 3 0 0 3 3 3 2 Leucine-rich repeat WASH-7_C PF14746.6 CDJ52100.1 - 0.0073 16.0 2.3 0.0073 16.0 2.3 6.5 5 2 2 7 7 7 1 WASH complex subunit 7, C-terminal OmpH PF03938.14 CDJ52100.1 - 0.0093 16.3 9.5 0.0093 16.3 9.5 8.5 6 3 2 8 8 8 1 Outer membrane protein (OmpH-like) LRR_6 PF13516.6 CDJ52100.1 - 7.1 7.0 12.1 6.5 7.1 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Hamartin PF04388.12 CDJ52101.1 - 2.8 6.5 58.4 3.6 6.1 58.4 1.2 1 0 0 1 1 1 0 Hamartin protein SR-25 PF10500.9 CDJ52102.1 - 0.008 15.8 37.4 0.008 15.8 37.4 6.0 4 2 2 6 6 6 3 Nuclear RNA-splicing-associated protein TMEM65 PF10507.9 CDJ52103.1 - 0.001 19.0 0.7 0.001 19.0 0.7 4.8 4 2 1 5 5 5 1 Transmembrane protein 65 ATP-synt_ab PF00006.25 CDJ52104.1 - 7.4e-29 100.9 0.1 1.1e-28 100.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain SelP_N PF04592.14 CDJ52105.1 - 4.6 6.6 34.0 5.4 6.4 34.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TBP PF00352.21 CDJ52107.1 - 0.00027 20.8 0.0 0.0011 18.9 0.0 2.2 2 1 0 2 2 2 1 Transcription factor TFIID (or TATA-binding protein, TBP) GHMP_kinases_N PF00288.26 CDJ52107.1 - 0.14 12.4 5.4 0.4 10.9 0.0 2.7 2 1 1 3 3 3 0 GHMP kinases N terminal domain LCIB_C_CA PF18599.1 CDJ52107.1 - 0.15 11.3 5.9 0.25 10.6 5.9 1.3 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases RskA PF10099.9 CDJ52107.1 - 0.16 12.3 9.0 0.34 11.2 8.9 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SurA_N_3 PF13624.6 CDJ52107.1 - 0.39 10.5 19.4 0.91 9.3 19.4 1.6 1 0 0 1 1 1 0 SurA N-terminal domain HA2 PF04408.23 CDJ52108.1 - 0.025 14.8 1.0 0.025 14.8 1.0 2.2 3 0 0 3 3 3 0 Helicase associated domain (HA2) EIF4E-T PF10477.9 CDJ52108.1 - 3.1 6.5 18.7 0.015 14.2 9.6 1.6 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Presenilin PF01080.17 CDJ52108.1 - 5 5.8 9.7 7.2 5.3 9.7 1.2 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 CDJ52108.1 - 7.1 6.9 54.7 0.11 12.8 25.5 2.9 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF3043 PF11241.8 CDJ52108.1 - 7.8 6.5 11.6 0.25 11.4 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF2207 PF09972.9 CDJ52109.1 - 1.4 7.6 4.2 1.5 7.5 3.1 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Connexin PF00029.19 CDJ52109.1 - 1.8 8.3 11.0 0.86 9.3 7.4 1.9 2 0 0 2 2 2 0 Connexin Band_3_cyto PF07565.13 CDJ52109.1 - 2.8 7.7 17.5 1.1 9.1 11.8 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain SpoIIP PF07454.11 CDJ52109.1 - 2.9 7.3 18.6 0.2 11.1 10.7 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CSN8_PSD8_EIF3K PF10075.9 CDJ52111.1 - 2e-13 50.6 0.0 6e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Dsh_C PF12316.8 CDJ52111.1 - 5.2 7.4 12.4 8.1 6.8 12.4 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RSRP PF17069.5 CDJ52112.1 - 1.5 8.3 15.2 3.9 7.0 15.2 1.7 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 DUF4667 PF15700.5 CDJ52112.1 - 2 8.5 15.4 0.85 9.7 12.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Sporozoite_P67 PF05642.11 CDJ52112.1 - 5 5.1 7.9 0.17 9.9 1.9 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF4834 PF16118.5 CDJ52112.1 - 6.8 7.7 14.0 0.97 10.4 2.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ52113.1 - 0.0082 15.1 13.1 0.01 14.8 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ52113.1 - 0.0099 16.5 6.9 0.014 16.1 6.9 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3292 PF11696.8 CDJ52113.1 - 0.021 13.2 3.2 0.025 13.0 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF3710 PF12502.8 CDJ52113.1 - 0.023 14.4 3.2 0.03 14.0 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) DUF4834 PF16118.5 CDJ52113.1 - 0.026 15.5 2.9 0.042 14.8 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ52113.1 - 0.034 13.8 18.1 0.046 13.3 18.1 1.2 1 0 0 1 1 1 0 Spt20 family DUF3837 PF12939.7 CDJ52113.1 - 0.036 14.5 0.1 0.051 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) FYDLN_acid PF09538.10 CDJ52113.1 - 0.05 14.3 1.0 0.05 14.3 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TFIIA PF03153.13 CDJ52113.1 - 0.087 12.8 18.9 0.093 12.7 18.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2368 PF10166.9 CDJ52113.1 - 0.17 11.5 8.0 0.26 10.9 8.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Neur_chan_memb PF02932.16 CDJ52113.1 - 0.3 11.1 1.8 0.31 11.1 1.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WES_acyltransf PF03007.16 CDJ52113.1 - 0.33 10.7 6.7 0.4 10.4 6.7 1.1 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Suf PF05843.14 CDJ52113.1 - 0.36 10.8 6.0 0.38 10.7 6.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 CDJ52113.1 - 0.42 10.7 7.2 0.5 10.4 7.2 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 CDJ52113.1 - 0.44 9.3 5.8 0.46 9.2 5.8 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 CDJ52113.1 - 3.1 6.2 9.6 3.5 6.1 9.6 1.0 1 0 0 1 1 1 0 Macoilin family Roughex PF06020.11 CDJ52113.1 - 3.4 6.7 9.5 4.1 6.4 9.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Activator_LAG-3 PF11498.8 CDJ52113.1 - 5.1 5.9 24.9 5.3 5.9 24.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EIIBC-GUT_N PF03612.14 CDJ52113.1 - 7.5 6.3 8.5 8.2 6.1 8.0 1.3 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AIF_C PF14721.6 CDJ52113.1 - 9 6.7 8.1 15 5.9 8.1 1.5 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PTS_2-RNA PF01885.16 CDJ52114.1 - 4.9e-11 43.0 4.7 1.4e-10 41.5 4.7 1.7 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Spt20 PF12090.8 CDJ52114.1 - 0.00047 19.8 19.1 0.00047 19.8 19.1 6.4 4 1 2 6 6 6 3 Spt20 family CDC45 PF02724.14 CDJ52114.1 - 4.2 5.6 37.3 0.13 10.6 6.4 3.5 3 0 0 3 3 3 0 CDC45-like protein Rrn6 PF10214.9 CDJ52115.1 - 3.5 6.0 24.2 3.1 6.2 24.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_S15 PF02129.18 CDJ52115.1 - 3.6 7.1 11.7 4.1 6.9 11.7 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SID-1_RNA_chan PF13965.6 CDJ52115.1 - 4.4 5.6 7.0 4.1 5.7 7.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1616 PF07760.11 CDJ52115.1 - 5.1 6.4 5.7 5.2 6.4 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Membralin PF09746.9 CDJ52115.1 - 5.7 5.9 11.3 5.4 5.9 11.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein V_ATPase_I PF01496.19 CDJ52115.1 - 5.8 4.7 18.2 7.5 4.3 18.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ52115.1 - 9.4 4.9 19.5 9 4.9 19.5 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ52116.1 - 0.0037 17.3 25.7 0.0037 17.3 25.7 3.3 2 1 1 3 3 3 2 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ52116.1 - 0.0068 16.0 15.7 0.0068 16.0 15.7 6.0 5 2 1 6 6 6 1 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 CDJ52116.1 - 0.0098 16.4 0.0 0.0098 16.4 0.0 3.5 4 0 0 4 4 4 1 AAA domain Ribosomal_60s PF00428.19 CDJ52116.1 - 0.022 15.3 0.7 0.022 15.3 0.7 5.1 4 1 0 4 4 4 0 60s Acidic ribosomal protein Lipase_GDSL_3 PF14606.6 CDJ52116.1 - 1.4 9.0 6.9 1.5 8.9 0.1 3.2 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family DUF4746 PF15928.5 CDJ52116.1 - 8.2 5.7 12.9 4.6 6.6 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4746) Lipase_GDSL PF00657.22 CDJ52118.1 - 0.019 14.9 29.0 0.13 12.2 0.0 5.9 3 2 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase Na_trans_assoc PF06512.13 CDJ52118.1 - 0.031 14.6 0.4 0.031 14.6 0.4 3.5 2 1 1 3 3 3 0 Sodium ion transport-associated SR-25 PF10500.9 CDJ52119.1 - 5.9e-10 39.1 31.8 8.1e-10 38.7 31.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein PAP1 PF08601.10 CDJ52119.1 - 0.035 13.8 32.6 0.044 13.5 32.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Pap_E4 PF02711.14 CDJ52119.1 - 0.06 14.3 2.3 0.06 14.3 2.3 3.1 1 1 2 3 3 3 0 E4 protein RAP1 PF07218.11 CDJ52119.1 - 0.13 10.5 4.3 0.13 10.5 4.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Caldesmon PF02029.15 CDJ52119.1 - 0.9 8.2 33.4 1.3 7.7 33.4 1.2 1 0 0 1 1 1 0 Caldesmon CAC1F_C PF16885.5 CDJ52119.1 - 3.1 7.4 30.1 4 7.0 30.1 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term zf-RanBP PF00641.18 CDJ52120.1 - 0.46 9.8 13.0 1.4 8.3 13.0 1.9 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF4131 PF13567.6 CDJ52121.1 - 0.0081 15.8 1.3 0.0081 15.8 1.3 3.0 2 2 0 2 2 2 1 Domain of unknown function (DUF4131) PIG-U PF06728.13 CDJ52121.1 - 3.1 6.8 7.4 3.7 6.5 3.0 2.1 2 0 0 2 2 2 0 GPI transamidase subunit PIG-U TerC PF03741.16 CDJ52121.1 - 3.7 7.2 5.1 0.42 10.3 0.3 1.9 2 0 0 2 2 2 0 Integral membrane protein TerC family SUIM_assoc PF16619.5 CDJ52122.1 - 0.00077 19.5 0.0 0.00077 19.5 0.0 16.8 11 4 2 13 13 13 3 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ52122.1 - 0.0022 17.0 3.8 0.0022 17.0 3.8 10.2 5 3 1 7 7 7 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52122.1 - 0.0091 15.6 10.0 0.0091 15.6 10.0 10.0 5 3 1 7 7 7 1 Spt20 family Ribosomal_60s PF00428.19 CDJ52123.1 - 0.95 10.1 14.4 3.7 8.2 7.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4834 PF16118.5 CDJ52123.1 - 7.5 7.6 22.1 18 6.4 2.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Alph_Pro_TM PF09608.10 CDJ52123.1 - 7.7 6.3 13.8 0.36 10.6 7.7 1.8 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) SART-1 PF03343.13 CDJ52124.1 - 3.7 6.0 35.1 5.6 5.4 35.1 1.2 1 0 0 1 1 1 0 SART-1 family MCM PF00493.23 CDJ52125.1 - 0.019 14.1 2.4 0.033 13.3 1.2 2.0 2 1 0 2 2 2 0 MCM P-loop domain Ribosomal_60s PF00428.19 CDJ52126.1 - 0.0032 18.0 4.9 0.0071 16.9 4.9 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ52126.1 - 0.3 11.0 31.5 0.45 10.5 31.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ52126.1 - 2.7 8.3 16.2 0.55 10.5 9.9 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA RAP1 PF07218.11 CDJ52126.1 - 5.7 5.1 8.3 8.3 4.5 8.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Chromo PF00385.24 CDJ52127.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF241 PF03087.14 CDJ52128.1 - 0.031 14.1 0.9 0.087 12.6 0.0 2.1 2 0 0 2 2 2 0 Arabidopsis protein of unknown function Vac7 PF12751.7 CDJ52131.1 - 0.19 11.1 1.5 0.3 10.5 1.5 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 C_Hendra PF16821.5 CDJ52133.1 - 0.016 15.1 1.1 0.049 13.5 1.1 1.8 1 0 0 1 1 1 0 C protein from hendra and measles viruses ASXH PF13919.6 CDJ52133.1 - 0.017 15.2 5.9 2.7 8.0 0.0 3.3 3 0 0 3 3 3 0 Asx homology domain Pacs-1 PF10254.9 CDJ52133.1 - 0.04 12.9 1.8 0.069 12.1 1.8 1.3 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Ribosomal_60s PF00428.19 CDJ52133.1 - 2.3 8.9 9.0 2.6 8.7 0.5 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Mon1 PF03164.14 CDJ52134.1 - 3.3e-50 171.4 0.0 3e-36 125.4 0.0 2.9 1 1 1 2 2 2 2 Trafficking protein Mon1 SET PF00856.28 CDJ52135.1 - 4.9e-11 43.3 0.0 1.4e-09 38.6 0.0 2.5 1 1 0 1 1 1 1 SET domain CTNNBL PF08216.11 CDJ52135.1 - 0.0027 17.8 0.3 0.12 12.5 0.0 2.7 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Brix PF04427.18 CDJ52136.1 - 9.5e-29 100.9 0.1 2.3e-28 99.6 0.1 1.7 1 0 0 1 1 1 1 Brix domain Evr1_Alr PF04777.13 CDJ52137.1 - 9.1e-10 38.9 0.2 8.7e-07 29.3 0.0 3.5 3 1 0 3 3 3 1 Erv1 / Alr family Thioredoxin PF00085.20 CDJ52137.1 - 2.5e-08 33.8 0.0 5.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CDJ52137.1 - 9.8e-05 22.5 0.0 0.00024 21.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CDJ52137.1 - 0.0014 19.1 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CDJ52137.1 - 0.0019 18.1 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ52137.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Redoxin CSTF1_dimer PF16699.5 CDJ52137.1 - 0.02 14.6 0.0 0.085 12.6 0.0 2.1 2 0 0 2 2 2 0 Cleavage stimulation factor subunit 1, dimerisation domain Thioredoxin_8 PF13905.6 CDJ52137.1 - 0.2 12.0 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like DUF35_N PF12172.8 CDJ52137.1 - 3.1 7.8 13.5 0.62 10.0 5.6 2.7 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FAM212 PF15342.6 CDJ52138.1 - 0.051 13.4 1.6 1.3 8.9 1.6 3.7 1 0 0 1 1 1 0 FAM212 family FAM181 PF15238.6 CDJ52140.1 - 2.9 7.7 7.5 0.72 9.6 0.8 2.4 2 0 0 2 2 2 0 FAM181 Glycophorin_A PF01102.18 CDJ52141.1 - 0.068 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A Coilin_N PF15862.5 CDJ52142.1 - 3.7e-06 26.8 0.0 1.3e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Coilin N-terminus FAM199X PF15814.5 CDJ52142.1 - 0.00054 19.1 4.7 0.00069 18.8 4.7 1.1 1 0 0 1 1 1 1 Protein family FAM199X SR-25 PF10500.9 CDJ52142.1 - 0.028 14.0 30.8 0.024 14.3 29.0 1.8 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ52142.1 - 0.069 13.7 12.2 0.088 13.4 12.2 1.1 1 0 0 1 1 1 0 TCP family transcription factor RNA_polI_A34 PF08208.11 CDJ52142.1 - 0.16 12.0 20.2 0.22 11.6 20.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Herpes_capsid PF06112.11 CDJ52142.1 - 0.66 10.0 9.6 0.89 9.6 9.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Chorion_2 PF03964.15 CDJ52142.1 - 1.2 10.1 9.9 1.8 9.4 9.9 1.5 1 1 0 1 1 1 0 Chorion family 2 Neur_chan_memb PF02932.16 CDJ52142.1 - 3.9 7.5 6.4 4.3 7.3 6.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dsh_C PF12316.8 CDJ52142.1 - 8.3 6.8 19.5 11 6.4 19.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal VIR_N PF15912.5 CDJ52143.1 - 0.0002 21.1 4.6 0.00021 21.0 4.6 1.1 1 0 0 1 1 1 1 Virilizer, N-terminal SUIM_assoc PF16619.5 CDJ52143.1 - 0.0038 17.3 10.4 0.0038 17.3 10.4 3.7 2 1 1 3 3 1 1 Unstructured region C-term to UIM in Ataxin3 MMR1 PF08505.10 CDJ52143.1 - 0.0054 17.1 15.2 0.0071 16.7 15.2 1.3 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein GAGA_bind PF06217.12 CDJ52143.1 - 0.0081 16.5 8.1 0.0084 16.4 8.1 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family Smg8_Smg9 PF10220.9 CDJ52143.1 - 0.022 13.1 11.5 0.025 12.9 11.5 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Ndc1_Nup PF09531.10 CDJ52143.1 - 0.073 11.7 20.0 0.079 11.6 20.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ52143.1 - 0.077 11.7 21.5 0.1 11.4 21.5 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ52143.1 - 0.11 12.5 9.7 0.16 11.9 9.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SAGA-Tad1 PF12767.7 CDJ52143.1 - 0.14 11.9 12.4 0.17 11.6 12.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Hid1 PF12722.7 CDJ52143.1 - 0.16 10.1 19.0 0.17 9.9 19.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein B12D PF06522.11 CDJ52143.1 - 0.16 11.8 0.0 0.48 10.3 0.0 1.8 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Macoilin PF09726.9 CDJ52143.1 - 0.25 9.9 12.4 0.32 9.5 12.4 1.2 1 0 0 1 1 1 0 Macoilin family CDK5_activator PF03261.15 CDJ52143.1 - 0.33 10.5 8.0 0.38 10.3 8.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SPX PF03105.19 CDJ52143.1 - 0.38 10.6 15.8 0.45 10.4 15.8 1.2 1 0 0 1 1 1 0 SPX domain DUF4551 PF15087.6 CDJ52143.1 - 0.58 8.9 13.0 0.63 8.8 13.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hamartin PF04388.12 CDJ52143.1 - 0.69 8.5 15.5 0.76 8.4 15.5 1.2 1 0 0 1 1 1 0 Hamartin protein PPP4R2 PF09184.11 CDJ52143.1 - 0.83 9.2 8.9 1.1 8.8 8.9 1.1 1 0 0 1 1 1 0 PPP4R2 PAT1 PF09770.9 CDJ52143.1 - 0.86 7.8 31.6 0.99 7.6 31.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Membralin PF09746.9 CDJ52143.1 - 1.4 7.9 7.1 1.7 7.6 7.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein GREB1 PF15782.5 CDJ52143.1 - 2.1 5.4 18.9 2.2 5.3 18.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Raftlin PF15250.6 CDJ52143.1 - 3 6.5 15.3 3.9 6.1 15.3 1.1 1 0 0 1 1 1 0 Raftlin Miga PF10265.9 CDJ52143.1 - 3.3 6.6 11.0 4.1 6.3 11.0 1.1 1 0 0 1 1 1 0 Mitoguardin MDM10 PF12519.8 CDJ52143.1 - 4.1 6.2 13.7 5 5.9 13.7 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 AF-4 PF05110.13 CDJ52143.1 - 4.2 5.3 27.6 5.3 5.0 27.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Herpes_DNAp_acc PF04929.12 CDJ52143.1 - 4.3 6.2 14.6 4.9 6.0 14.6 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor XRN_M PF17846.1 CDJ52143.1 - 4.9 6.0 15.6 7.3 5.4 15.6 1.2 1 0 0 1 1 1 0 Xrn1 helical domain RskA PF10099.9 CDJ52143.1 - 5.9 7.1 50.7 0.29 11.4 35.1 2.2 1 1 1 2 2 1 0 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ52143.1 - 6.3 5.9 28.2 9.3 5.3 28.2 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region DUF2052 PF09747.9 CDJ52143.1 - 6.4 6.9 20.3 9.8 6.2 20.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SAPS PF04499.15 CDJ52143.1 - 6.5 5.4 12.2 7.4 5.2 12.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 CDJ52143.1 - 7.1 5.5 19.2 9.2 5.2 19.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Suf PF05843.14 CDJ52143.1 - 7.2 6.5 27.3 11 5.9 27.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LMBR1 PF04791.16 CDJ52143.1 - 7.8 5.3 5.9 8.5 5.2 5.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MAJIN PF15077.6 CDJ52143.1 - 9 6.0 12.8 17 5.1 12.8 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein MTBP_C PF14920.6 CDJ52143.1 - 9.8 5.8 20.2 14 5.3 20.2 1.2 1 0 0 1 1 1 0 MDM2-binding DUF1501 PF07394.12 CDJ52144.1 - 0.62 9.1 15.1 0.7 8.9 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Neur_chan_memb PF02932.16 CDJ52144.1 - 1.2 9.1 5.8 1.4 8.9 5.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 CDJ52145.1 - 0.0013 17.7 14.0 0.0017 17.3 14.0 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain EBP PF05241.12 CDJ52145.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Emopamil binding protein Peptidase_S64 PF08192.11 CDJ52145.1 - 0.62 8.5 15.0 0.6 8.5 15.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 SOBP PF15279.6 CDJ52145.1 - 1.6 9.3 11.4 1.8 9.1 11.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.10 CDJ52145.1 - 3.3 6.3 14.6 4.6 5.8 14.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Utp14 PF04615.13 CDJ52145.1 - 7.5 5.0 15.9 8.5 4.8 15.9 1.2 1 0 0 1 1 1 0 Utp14 protein MAP65_ASE1 PF03999.12 CDJ52145.1 - 8.2 5.0 11.6 9.4 4.8 11.6 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RskA PF10099.9 CDJ52146.1 - 1.5e-05 25.3 30.4 0.0022 18.3 3.4 2.5 2 1 0 2 2 2 2 Anti-sigma-K factor rskA DUF4667 PF15700.5 CDJ52146.1 - 0.00055 20.1 14.2 0.0084 16.2 6.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ52146.1 - 0.00089 18.9 22.3 0.008 15.8 9.6 2.3 2 0 0 2 2 2 2 Spt20 family Ribosomal_60s PF00428.19 CDJ52146.1 - 0.0016 19.0 11.2 0.0016 19.0 11.2 3.0 4 0 0 4 4 3 1 60s Acidic ribosomal protein Lin-8 PF03353.15 CDJ52146.1 - 0.0019 17.8 11.0 0.12 11.9 0.9 2.1 2 0 0 2 2 2 2 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ52146.1 - 0.0089 16.1 28.7 0.013 15.6 28.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cu2_monooxygen PF01082.20 CDJ52146.1 - 0.043 14.0 2.7 8.1 6.7 0.0 3.0 3 0 0 3 3 3 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DUF1178 PF06676.11 CDJ52146.1 - 0.045 14.1 1.1 0.045 14.1 1.1 3.2 2 1 0 2 2 1 0 Protein of unknown function (DUF1178) IHABP4_N PF16174.5 CDJ52146.1 - 0.053 14.1 13.4 0.69 10.5 0.1 2.5 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal SPX PF03105.19 CDJ52146.1 - 0.34 10.8 11.0 2.6 7.9 11.0 1.9 1 1 0 1 1 1 0 SPX domain SR-25 PF10500.9 CDJ52146.1 - 2.4 7.7 38.1 0.16 11.6 10.2 3.7 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein Mog1 PF04603.12 CDJ52146.1 - 2.8 8.3 6.1 0.48 10.8 0.7 2.3 1 1 0 2 2 2 0 Ran-interacting Mog1 protein DUF2722 PF10846.8 CDJ52146.1 - 3.6 6.4 29.9 0.017 14.1 4.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2722) HMG_box PF00505.19 CDJ52147.1 - 3.4e-09 37.0 6.2 5.2e-09 36.4 6.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ52147.1 - 0.00015 22.3 8.9 0.00015 22.3 8.9 1.7 2 0 0 2 2 2 1 HMG-box domain KRAB PF01352.27 CDJ52147.1 - 0.025 14.2 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 KRAB box V_ATPase_I PF01496.19 CDJ52147.1 - 0.026 12.5 2.5 0.028 12.4 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4820 PF16091.5 CDJ52147.1 - 0.044 13.1 2.5 0.049 13.0 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CCDC53 PF10152.9 CDJ52147.1 - 0.064 13.7 9.4 0.081 13.3 9.4 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Androgen_recep PF02166.16 CDJ52147.1 - 0.089 11.6 16.1 0.095 11.5 16.1 1.1 1 0 0 1 1 1 0 Androgen receptor DUF1178 PF06676.11 CDJ52147.1 - 0.096 13.1 8.3 0.12 12.8 8.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) FAM176 PF14851.6 CDJ52147.1 - 0.17 11.5 1.4 0.2 11.3 1.4 1.2 1 0 0 1 1 1 0 FAM176 family PepSY_TM PF03929.16 CDJ52147.1 - 0.32 10.6 0.7 0.35 10.5 0.7 1.1 1 0 0 1 1 1 0 PepSY-associated TM region DUF1180 PF06679.12 CDJ52147.1 - 0.4 11.1 4.2 0.43 11.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3530 PF12048.8 CDJ52147.1 - 1.5 8.2 16.0 0.11 11.9 10.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3530) Presenilin PF01080.17 CDJ52147.1 - 1.7 7.4 8.2 1.7 7.3 8.2 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ52147.1 - 4.2 7.1 13.1 5.1 6.8 13.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5327 PF17261.2 CDJ52147.1 - 4.3 8.2 13.9 13 6.6 13.9 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5327) Spore_coat_CotO PF14153.6 CDJ52147.1 - 4.4 7.2 17.7 5.5 6.9 17.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Hid1 PF12722.7 CDJ52147.1 - 5 5.1 5.9 4.6 5.2 5.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AIF_C PF14721.6 CDJ52147.1 - 6.4 7.1 7.3 13 6.2 7.3 1.5 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PIP5K PF01504.18 CDJ52148.1 - 0.11 11.7 0.0 0.11 11.7 0.0 4.6 4 1 0 4 4 4 0 Phosphatidylinositol-4-phosphate 5-Kinase Comm PF15957.5 CDJ52149.1 - 2.4 8.5 8.6 2.8 8.3 8.6 1.1 1 0 0 1 1 1 0 Commissureless Coilin_N PF15862.5 CDJ52149.1 - 4 7.3 21.6 5 6.9 21.6 1.3 1 0 0 1 1 1 0 Coilin N-terminus Metallophos PF00149.28 CDJ52150.1 - 1.2e-11 45.5 0.5 3.3e-11 44.1 0.5 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPR_2 PF13041.6 CDJ52151.1 - 8.8e-21 73.9 0.0 4.9e-10 39.4 0.0 4.2 2 1 2 4 4 4 2 PPR repeat family PPR_3 PF13812.6 CDJ52151.1 - 7.3e-14 51.6 0.1 5.8e-06 26.3 0.0 2.9 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 CDJ52151.1 - 4.3e-13 48.7 0.0 0.00041 20.0 0.0 4.5 4 0 0 4 4 4 3 PPR repeat PPR PF01535.20 CDJ52151.1 - 2.6e-10 39.8 0.1 0.0024 18.0 0.0 5.1 4 1 0 4 4 4 2 PPR repeat PPR_long PF17177.4 CDJ52151.1 - 7.9e-06 25.4 0.3 7.9e-06 25.4 0.3 3.3 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP MSP1_C PF07462.11 CDJ52151.1 - 0.42 9.3 4.9 0.96 8.1 4.9 1.5 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SARAF PF06682.12 CDJ52151.1 - 1 9.0 17.8 1.9 8.0 17.8 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis FAM176 PF14851.6 CDJ52151.1 - 1.2 8.8 5.7 3.6 7.2 0.5 2.3 2 0 0 2 2 2 0 FAM176 family EIF4E-T PF10477.9 CDJ52151.1 - 5.4 5.7 28.8 7.3 5.3 28.8 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Utp14 PF04615.13 CDJ52152.1 - 9.8 4.6 89.9 0.27 9.8 17.2 2.3 2 0 0 2 2 2 0 Utp14 protein Mitofilin PF09731.9 CDJ52153.1 - 0.097 11.5 17.9 0.12 11.2 17.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF294_C PF10335.9 CDJ52153.1 - 0.24 11.2 5.1 3.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain TFIIA PF03153.13 CDJ52153.1 - 0.28 11.2 19.1 0.35 10.8 19.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CDJ52153.1 - 9.6 5.5 16.6 13 5.0 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ERCC3_RAD25_C PF16203.5 CDJ52154.1 - 3.4e-44 150.9 6.3 6.1e-20 71.5 0.0 6.5 4 2 2 6 6 6 3 ERCC3/RAD25/XPB C-terminal helicase Helicase_C PF00271.31 CDJ52154.1 - 0.019 15.3 0.3 0.019 15.3 0.3 3.8 4 1 0 5 5 5 0 Helicase conserved C-terminal domain Shadoo PF14999.6 CDJ52154.1 - 0.9 9.6 17.6 0.66 10.1 2.5 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective RAP1 PF07218.11 CDJ52155.1 - 4.7 5.4 12.5 4.6 5.4 12.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RabGAP-TBC PF00566.18 CDJ52156.1 - 7.4e-10 38.8 0.0 8.6e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Antimicrobial14 PF08109.11 CDJ52156.1 - 0.046 13.7 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Lactocin 705 family SVIP PF15811.5 CDJ52157.1 - 0.66 10.5 18.6 0.94 10.0 18.6 1.2 1 0 0 1 1 1 0 Small VCP/p97-interacting protein G0-G1_switch_2 PF15103.6 CDJ52157.1 - 0.8 10.2 9.0 1 9.8 9.0 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 CobT PF06213.12 CDJ52157.1 - 0.99 8.7 16.3 1 8.7 16.3 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HAUS6_N PF14661.6 CDJ52157.1 - 1.8 8.1 16.2 1.9 8.0 16.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus BBS2_C PF14782.6 CDJ52157.1 - 3 6.5 14.3 3.1 6.4 14.3 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Coilin_N PF15862.5 CDJ52157.1 - 4.1 7.2 14.4 6.1 6.6 14.4 1.3 1 0 0 1 1 1 0 Coilin N-terminus Pex14_N PF04695.13 CDJ52157.1 - 5.4 7.7 20.1 5.9 7.5 20.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gastrin PF00918.17 CDJ52157.1 - 5.5 8.0 12.4 5.6 8.0 12.4 1.0 1 0 0 1 1 1 0 Gastrin/cholecystokinin family V_ATPase_I PF01496.19 CDJ52157.1 - 7.8 4.3 13.4 7.8 4.3 13.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec62 PF03839.16 CDJ52157.1 - 9 5.7 10.3 9.5 5.7 10.3 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 TFIIA PF03153.13 CDJ52157.1 - 9.3 6.1 30.5 9.6 6.1 30.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AUX_IAA PF02309.16 CDJ52158.1 - 0.028 14.3 0.9 0.028 14.3 0.9 3.2 1 1 0 3 3 3 0 AUX/IAA family RskA PF10099.9 CDJ52158.1 - 1.2 9.4 26.8 0.016 15.5 14.2 2.7 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Utp14 PF04615.13 CDJ52158.1 - 7.2 5.1 29.8 6.8 5.1 28.9 1.4 1 1 1 2 2 2 0 Utp14 protein YbgS PF13985.6 CDJ52160.1 - 1 9.7 15.8 2.3 8.5 15.8 1.5 1 0 0 1 1 1 0 YbgS-like protein KH_1 PF00013.29 CDJ52161.1 - 3.8e-10 39.4 0.0 0.00015 21.5 0.0 3.3 3 0 0 3 3 3 2 KH domain TraT PF05818.12 CDJ52161.1 - 0.008 15.9 1.0 0.015 15.0 1.0 1.5 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Pkinase PF00069.25 CDJ52162.1 - 4.7e-80 268.7 0.0 7.1e-80 268.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ52162.1 - 1.7e-36 125.8 0.0 2.5e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ52162.1 - 2.7e-16 57.8 0.8 1.4e-08 33.7 1.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ52162.1 - 9.1e-13 48.5 0.1 1.3e-11 44.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ52162.1 - 1.7e-12 46.2 0.4 4.1e-05 23.2 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ52162.1 - 5.9e-12 45.3 0.5 3e-07 30.2 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ52162.1 - 2.3e-11 42.7 2.3 0.00019 20.8 1.3 2.5 2 0 0 2 2 2 2 EF hand Pkinase_fungal PF17667.1 CDJ52162.1 - 3.3e-06 26.2 0.0 5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ52162.1 - 0.00012 21.5 0.0 0.00022 20.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ52162.1 - 0.00027 20.9 0.0 0.00057 19.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ52162.1 - 0.021 14.2 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.6 CDJ52162.1 - 0.031 14.6 0.1 3.7 7.9 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 CDJ52162.1 - 0.058 13.6 0.1 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Dockerin type I domain FTA2 PF13095.6 CDJ52162.1 - 0.12 12.0 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TSC22 PF01166.18 CDJ52163.1 - 0.19 12.1 0.3 0.19 12.1 0.3 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family Cytochrom_B562 PF07361.11 CDJ52163.1 - 0.68 10.6 5.0 2 9.1 0.2 3.0 2 1 1 3 3 3 0 Cytochrome b562 NRBF2 PF08961.10 CDJ52163.1 - 0.81 9.3 10.6 0.42 10.2 0.2 2.9 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator DUF4208 PF13907.6 CDJ52163.1 - 2.4 8.7 4.5 3 8.3 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) YabA PF06156.13 CDJ52163.1 - 7.5 7.3 7.7 29 5.4 0.9 2.9 2 1 0 3 3 3 0 Initiation control protein YabA CDC45 PF02724.14 CDJ52166.1 - 2.1 6.5 36.4 2.2 6.5 36.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ52166.1 - 4.6 7.0 37.8 6.2 6.6 37.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 CDJ52166.1 - 5.5 6.3 27.2 7.3 5.9 27.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF5427 PF10310.9 CDJ52166.1 - 7.6 5.4 35.8 11 4.8 35.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) RskA PF10099.9 CDJ52167.1 - 2.1e-05 24.9 13.8 2.1e-05 24.9 13.8 5.4 1 1 3 4 4 4 1 Anti-sigma-K factor rskA DUF1980 PF09323.10 CDJ52167.1 - 0.037 13.9 5.4 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) SAP18 PF06487.12 CDJ52167.1 - 0.12 12.5 3.1 5.6 7.1 0.5 2.4 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) eIF-3_zeta PF05091.12 CDJ52167.1 - 0.79 8.6 16.5 0.7 8.8 7.6 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 CDJ52167.1 - 1.2 8.8 4.6 2.9 7.6 1.7 2.2 2 0 0 2 2 2 0 Connexin V_ATPase_I PF01496.19 CDJ52167.1 - 3.5 5.4 10.2 0.95 7.3 4.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CSG2 PF16965.5 CDJ52167.1 - 6.8 5.5 4.9 14 4.5 2.0 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator Spt20 PF12090.8 CDJ52168.1 - 0.0025 17.5 12.6 0.0025 17.5 12.6 1.2 1 0 0 1 1 1 1 Spt20 family SprA-related PF12118.8 CDJ52168.1 - 0.0067 15.6 19.4 0.0072 15.5 19.4 1.0 1 0 0 1 1 1 1 SprA-related family SelP_N PF04592.14 CDJ52168.1 - 0.013 14.9 6.9 0.014 14.8 6.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIA PF03153.13 CDJ52168.1 - 0.056 13.5 24.8 0.062 13.3 24.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Miga PF10265.9 CDJ52168.1 - 0.063 12.3 1.7 0.066 12.2 1.7 1.2 1 0 0 1 1 1 0 Mitoguardin Hydin_ADK PF17213.3 CDJ52168.1 - 0.19 12.0 9.8 0.23 11.7 9.8 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RAB3GAP2_N PF14655.6 CDJ52168.1 - 0.23 10.7 4.9 0.27 10.4 4.9 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2722 PF10846.8 CDJ52168.1 - 0.26 10.2 15.8 0.39 9.6 15.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Peptidase_S49_N PF08496.10 CDJ52168.1 - 0.35 10.9 5.4 0.42 10.7 5.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM199X PF15814.5 CDJ52168.1 - 0.39 9.7 9.9 0.46 9.5 9.9 1.0 1 0 0 1 1 1 0 Protein family FAM199X BAT2_N PF07001.11 CDJ52168.1 - 0.48 10.8 16.5 0.71 10.3 16.5 1.3 1 0 0 1 1 1 0 BAT2 N-terminus Suf PF05843.14 CDJ52168.1 - 0.66 9.9 13.7 0.73 9.8 13.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ52168.1 - 0.81 9.7 3.7 0.93 9.5 3.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Roughex PF06020.11 CDJ52168.1 - 1.1 8.2 7.8 1.2 8.2 7.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Dehydrin PF00257.19 CDJ52168.1 - 1.5 9.4 10.5 2.3 8.7 10.5 1.3 1 0 0 1 1 1 0 Dehydrin OmpH PF03938.14 CDJ52168.1 - 1.5 9.1 21.1 1.8 8.9 21.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Presenilin PF01080.17 CDJ52168.1 - 2 7.1 13.2 2.1 7.0 13.2 1.0 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.12 CDJ52168.1 - 3 7.1 10.5 3.4 7.0 10.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger GREB1 PF15782.5 CDJ52168.1 - 5.5 4.0 10.8 6.2 3.8 10.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BAF1_ABF1 PF04684.13 CDJ52168.1 - 6.3 5.7 13.9 8.3 5.3 13.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor R_equi_Vir PF05526.11 CDJ52168.1 - 10 6.0 13.0 15 5.4 13.0 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Eapp_C PF10238.9 CDJ52169.1 - 0.0003 20.9 10.3 0.0003 20.9 10.3 2.9 3 0 0 3 3 3 1 E2F-associated phosphoprotein Caldesmon PF02029.15 CDJ52169.1 - 0.00099 18.0 16.8 0.0016 17.3 16.8 1.3 1 0 0 1 1 1 1 Caldesmon DUF4746 PF15928.5 CDJ52169.1 - 0.0031 17.0 6.8 0.0031 17.0 6.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4746) GramPos_pilinD1 PF16555.5 CDJ52169.1 - 0.0062 16.7 6.6 0.0062 16.7 6.6 1.9 2 1 0 2 2 2 1 Gram-positive pilin subunit D1, N-terminal domain Utp14 PF04615.13 CDJ52169.1 - 0.0065 15.1 17.8 0.0081 14.8 17.8 1.1 1 0 0 1 1 1 1 Utp14 protein RskA PF10099.9 CDJ52169.1 - 0.0068 16.7 21.5 0.0068 16.7 21.5 2.4 1 1 0 2 2 2 1 Anti-sigma-K factor rskA AAA_23 PF13476.6 CDJ52169.1 - 0.14 12.6 29.4 0.022 15.3 21.5 2.2 2 0 0 2 2 2 0 AAA domain SID-1_RNA_chan PF13965.6 CDJ52169.1 - 0.14 10.5 6.3 0.17 10.3 6.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TERB2 PF15101.6 CDJ52169.1 - 1.4 8.9 38.4 2.4 8.2 20.4 3.0 3 0 0 3 3 3 0 Telomere-associated protein TERB2 MMU163 PF17119.5 CDJ52169.1 - 1.9 7.6 8.8 0.18 11.0 2.1 2.1 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis DUF5327 PF17261.2 CDJ52169.1 - 3.9 8.3 38.4 5.4 7.8 20.5 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Vfa1 PF08432.10 CDJ52169.1 - 5 7.4 26.3 0.23 11.8 12.3 2.9 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 DUF3449 PF11931.8 CDJ52169.1 - 6.2 6.6 22.8 0.9 9.3 14.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3449) DUF572 PF04502.13 CDJ52169.1 - 6.3 6.3 22.6 2.9 7.4 19.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) TRAP_alpha PF03896.16 CDJ52169.1 - 7.3 5.7 14.3 0.22 10.7 6.3 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SUIM_assoc PF16619.5 CDJ52170.1 - 0.0085 16.1 0.1 0.0085 16.1 0.1 10.9 7 2 3 10 10 10 1 Unstructured region C-term to UIM in Ataxin3 DUF755 PF05501.11 CDJ52170.1 - 0.017 15.4 1.6 0.017 15.4 1.6 7.0 6 2 0 6 6 6 0 Domain of unknown function (DUF755) IMUP PF15761.5 CDJ52172.1 - 0.0044 17.7 8.0 0.0058 17.3 8.0 1.2 1 0 0 1 1 1 1 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ52172.1 - 0.0049 16.5 17.2 0.0053 16.4 17.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 CDJ52172.1 - 0.031 14.0 16.6 0.033 13.9 16.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Spt20 PF12090.8 CDJ52172.1 - 0.048 13.3 25.4 0.052 13.2 25.4 1.0 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ52172.1 - 0.09 13.7 14.2 0.1 13.5 14.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF1676 PF07898.13 CDJ52172.1 - 0.23 11.5 3.6 0.31 11.1 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) OATP PF03137.20 CDJ52172.1 - 0.67 8.2 6.4 0.73 8.1 6.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RR_TM4-6 PF06459.12 CDJ52172.1 - 0.68 9.7 13.8 0.66 9.7 13.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med19 PF10278.9 CDJ52172.1 - 0.76 9.7 17.4 0.83 9.6 17.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNA_pol_Rpc4 PF05132.14 CDJ52172.1 - 0.91 9.9 16.7 1.1 9.7 16.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Band_3_cyto PF07565.13 CDJ52172.1 - 1.9 8.2 14.0 2.1 8.1 14.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AXIN1_TNKS_BD PF16646.5 CDJ52172.1 - 1.9 9.5 14.3 0.073 14.0 4.9 2.1 1 1 1 2 2 2 0 Axin-1 tankyrase binding domain TSA PF03249.13 CDJ52172.1 - 2.1 7.1 8.0 2.3 6.9 8.0 1.0 1 0 0 1 1 1 0 Type specific antigen DDHD PF02862.17 CDJ52172.1 - 3.8 7.6 11.3 3.8 7.6 11.3 1.1 1 0 0 1 1 1 0 DDHD domain PPL5 PF18168.1 CDJ52172.1 - 4.2 6.6 10.1 4.1 6.6 10.1 1.1 1 0 0 1 1 1 0 Prim-pol family 5 ALMT PF11744.8 CDJ52172.1 - 4.2 6.1 10.6 4.3 6.1 10.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3381 PF11861.8 CDJ52172.1 - 4.6 7.0 23.0 5.2 6.8 23.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CNDH2_M PF16869.5 CDJ52172.1 - 4.6 7.9 11.1 5.5 7.7 11.1 1.2 1 0 0 1 1 1 0 PF16858 DUF1980 PF09323.10 CDJ52172.1 - 5.8 6.8 10.0 6.6 6.6 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) TFIIA PF03153.13 CDJ52172.1 - 5.9 6.8 23.9 6 6.8 23.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 CDJ52172.1 - 7 5.3 15.2 8.5 5.1 15.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YABBY PF04690.13 CDJ52172.1 - 7.7 7.1 15.7 8.4 6.9 15.7 1.0 1 0 0 1 1 1 0 YABBY protein TFIIA PF03153.13 CDJ52174.1 - 0.00035 20.7 33.3 0.00043 20.4 33.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ52174.1 - 0.053 12.6 7.5 0.058 12.5 7.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Serinc PF03348.15 CDJ52174.1 - 0.2 10.5 7.7 0.29 10.0 7.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) PBP_sp32 PF07222.12 CDJ52174.1 - 0.79 9.1 12.3 1.2 8.5 12.3 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF2079 PF09852.9 CDJ52174.1 - 0.98 8.2 7.0 1.3 7.8 7.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) eIF-3_zeta PF05091.12 CDJ52174.1 - 1.1 8.2 16.9 1.2 8.0 16.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Activator_LAG-3 PF11498.8 CDJ52174.1 - 1.6 7.7 47.2 2.2 7.2 47.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Neur_chan_memb PF02932.16 CDJ52174.1 - 1.6 8.8 10.3 0.36 10.9 7.6 1.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ52174.1 - 1.8 7.5 8.2 2.7 6.9 8.2 1.3 1 0 0 1 1 1 0 CLN3 protein EOS1 PF12326.8 CDJ52174.1 - 1.9 8.4 6.1 2.7 7.9 6.1 1.4 1 1 0 1 1 1 0 N-glycosylation protein Herpes_glycop PF01528.16 CDJ52174.1 - 1.9 7.2 3.6 2.6 6.8 3.6 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Peptidase_S49_N PF08496.10 CDJ52174.1 - 2.8 8.0 12.3 4.9 7.2 12.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Suf PF05843.14 CDJ52174.1 - 3.1 7.7 16.7 4.5 7.2 16.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TraT PF05818.12 CDJ52174.1 - 3.3 7.3 22.4 0.11 12.2 15.6 1.9 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein CPSF73-100_C PF11718.8 CDJ52174.1 - 4.6 6.7 10.7 21 4.6 0.1 2.2 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term P5-ATPase PF12409.8 CDJ52174.1 - 4.9 7.3 6.0 9.4 6.4 6.0 1.4 1 0 0 1 1 1 0 P5-type ATPase cation transporter RR_TM4-6 PF06459.12 CDJ52174.1 - 6.6 6.5 13.4 9.3 6.0 13.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 CDJ52174.1 - 9 6.0 9.5 12 5.5 9.5 1.2 1 0 0 1 1 1 0 Connexin SLM4 PF16818.5 CDJ52174.1 - 9.1 6.2 9.2 4.4 7.3 3.7 2.2 2 0 0 2 2 2 0 Protein SLM4 HEAT PF02985.22 CDJ52176.1 - 0.00018 21.5 30.6 0.0066 16.6 0.3 7.9 7 0 0 7 7 7 4 HEAT repeat DUF4042 PF13251.6 CDJ52176.1 - 0.012 15.4 0.1 0.012 15.4 0.1 3.9 3 1 0 4 4 4 0 Domain of unknown function (DUF4042) ATP11 PF06644.11 CDJ52176.1 - 0.3 10.8 1.4 0.96 9.2 1.4 2.0 1 0 0 1 1 1 0 ATP11 protein RPA43_OB PF17875.1 CDJ52177.1 - 0.37 11.4 10.2 0.46 11.1 10.2 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I SpoIIP PF07454.11 CDJ52177.1 - 0.51 9.8 18.0 0.49 9.8 18.0 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CCDC53 PF10152.9 CDJ52177.1 - 1.2 9.6 18.5 1.3 9.4 18.5 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2126 PF09899.9 CDJ52177.1 - 1.4 6.9 14.1 1.3 7.0 14.1 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Endostatin PF06482.11 CDJ52177.1 - 2.1 7.7 18.9 2.2 7.7 18.9 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Lin-8 PF03353.15 CDJ52177.1 - 2.1 7.8 24.6 2.3 7.7 24.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CPSF100_C PF13299.6 CDJ52177.1 - 2.3 8.4 14.9 2.8 8.1 14.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal EPL1 PF10513.9 CDJ52177.1 - 2.6 8.4 18.3 3.2 8.1 18.3 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Eapp_C PF10238.9 CDJ52177.1 - 3.8 7.6 19.7 4.5 7.3 19.7 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein RRP36 PF06102.12 CDJ52177.1 - 3.9 7.4 25.2 4.1 7.4 25.2 1.1 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 TFIIA PF03153.13 CDJ52177.1 - 4.2 7.3 45.3 4.6 7.1 45.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MDM31_MDM32 PF08118.11 CDJ52177.1 - 4.4 5.9 14.2 5 5.7 14.2 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins FAM176 PF14851.6 CDJ52177.1 - 4.5 6.9 14.0 5.2 6.7 14.0 1.1 1 0 0 1 1 1 0 FAM176 family Paf1 PF03985.13 CDJ52177.1 - 5.3 5.9 23.7 5.5 5.9 23.7 1.1 1 0 0 1 1 1 0 Paf1 Connexin PF00029.19 CDJ52177.1 - 5.4 6.7 19.0 6.1 6.5 19.0 1.0 1 0 0 1 1 1 0 Connexin DUF1764 PF08576.10 CDJ52177.1 - 5.8 7.9 16.4 7.1 7.6 16.4 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Velvet PF11754.8 CDJ52177.1 - 5.9 6.8 18.5 6 6.7 18.5 1.2 1 0 0 1 1 1 0 Velvet factor FAM60A PF15396.6 CDJ52177.1 - 6.3 6.7 17.1 6.7 6.7 17.1 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.17 CDJ52177.1 - 6.5 6.8 17.9 6.7 6.8 17.9 1.1 1 0 0 1 1 1 0 DDHD domain Peptidase_S49_N PF08496.10 CDJ52177.1 - 7 6.7 19.5 8.2 6.5 19.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Membralin PF09746.9 CDJ52177.1 - 7.2 5.5 14.8 7.4 5.5 14.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein Plexin_cytopl PF08337.12 CDJ52177.1 - 7.3 5.1 17.3 7.6 5.1 17.3 1.0 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain Tim54 PF11711.8 CDJ52177.1 - 7.6 5.2 17.3 7.9 5.2 17.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Mem_trans PF03547.18 CDJ52177.1 - 7.7 4.8 7.0 8.2 4.7 7.0 1.0 1 0 0 1 1 1 0 Membrane transport protein Presenilin PF01080.17 CDJ52177.1 - 7.8 5.1 25.0 8.2 5.1 25.0 1.0 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 CDJ52177.1 - 8 5.4 18.7 8.2 5.3 18.7 1.0 1 0 0 1 1 1 0 CLN3 protein NPR3 PF03666.13 CDJ52177.1 - 8.9 5.0 18.1 8.9 5.0 18.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 EBP50_C PF09007.11 CDJ52177.1 - 9 7.3 19.5 9.8 7.2 19.5 1.0 1 0 0 1 1 1 0 EBP50, C-terminal RPN2_C PF18004.1 CDJ52177.1 - 9.1 6.2 19.0 9.8 6.1 19.0 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain AIF_C PF14721.6 CDJ52177.1 - 9.4 6.6 15.5 13 6.2 15.5 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EphA2_TM PF14575.6 CDJ52178.1 - 0.056 14.3 0.9 0.19 12.6 0.9 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FTR1 PF03239.14 CDJ52178.1 - 0.059 12.5 0.2 0.12 11.5 0.1 1.5 1 1 1 2 2 2 0 Iron permease FTR1 family START PF01852.19 CDJ52178.1 - 0.1 12.0 0.4 0.15 11.5 0.4 1.2 1 0 0 1 1 1 0 START domain Dehydrin PF00257.19 CDJ52178.1 - 0.14 12.7 1.5 0.21 12.1 0.4 1.8 2 0 0 2 2 2 0 Dehydrin FxsA PF04186.13 CDJ52178.1 - 0.3 11.2 3.2 6.7 6.9 0.0 2.2 1 1 0 2 2 2 0 FxsA cytoplasmic membrane protein NINJA_B PF16136.5 CDJ52178.1 - 0.35 11.3 4.6 0.92 9.9 0.9 2.1 2 0 0 2 2 2 0 Putative nuclear localisation signal Roughex PF06020.11 CDJ52178.1 - 0.96 8.5 5.4 2.4 7.2 0.6 2.0 2 0 0 2 2 2 0 Drosophila roughex protein YajC PF02699.15 CDJ52178.1 - 1.2 9.1 7.8 0.9 9.5 0.2 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit IMUP PF15761.5 CDJ52178.1 - 1.3 9.8 7.6 0.57 10.9 2.9 2.4 3 0 0 3 3 3 0 Immortalisation up-regulated protein SUIM_assoc PF16619.5 CDJ52178.1 - 2.8 8.1 19.3 2.2 8.4 3.2 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ52178.1 - 3.5 7.2 11.5 9.1 5.8 11.4 1.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ52179.1 - 6.3e-07 28.5 34.0 4e-05 22.6 29.5 2.1 2 0 0 2 2 2 2 Presenilin CDC45 PF02724.14 CDJ52179.1 - 4.7e-05 21.9 28.0 7.8e-05 21.2 28.0 1.2 1 0 0 1 1 1 1 CDC45-like protein MDH PF02315.16 CDJ52179.1 - 0.0011 19.0 0.6 0.0011 19.0 0.6 4.1 3 1 1 4 4 1 1 Methanol dehydrogenase beta subunit DUF2722 PF10846.8 CDJ52179.1 - 0.0036 16.3 5.9 0.0036 16.3 5.9 3.9 2 1 1 3 3 1 1 Protein of unknown function (DUF2722) SLC12 PF03522.15 CDJ52179.1 - 0.082 11.9 37.6 0.1 11.6 30.3 2.1 2 0 0 2 2 2 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ52179.1 - 0.14 11.9 38.9 0.94 9.2 31.3 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Anoctamin PF04547.12 CDJ52179.1 - 0.23 10.2 0.0 0.23 10.2 0.0 3.0 2 1 0 2 2 1 0 Calcium-activated chloride channel Dapper PF15268.6 CDJ52179.1 - 0.29 10.0 47.8 0.43 9.4 47.8 1.2 1 0 0 1 1 1 0 Dapper K_trans PF02705.16 CDJ52179.1 - 0.29 9.6 0.0 0.29 9.6 0.0 2.3 2 1 0 2 2 1 0 K+ potassium transporter Smg8_Smg9 PF10220.9 CDJ52179.1 - 0.5 8.6 29.9 0.097 11.0 22.1 2.0 2 0 0 2 2 2 0 Smg8_Smg9 DUF4045 PF13254.6 CDJ52179.1 - 1.1 8.9 35.1 0.098 12.3 25.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) MCM_bind PF09739.9 CDJ52179.1 - 1.8 6.9 34.6 0.13 10.7 24.4 2.2 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor DUF5427 PF10310.9 CDJ52179.1 - 1.8 7.4 39.3 0.31 9.9 27.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5427) CCSAP PF15748.5 CDJ52179.1 - 2.3 8.3 46.6 3.7 7.6 37.0 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated AAA_11 PF13086.6 CDJ52179.1 - 2.6 7.7 36.8 10 5.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain Mcm10 PF09332.11 CDJ52179.1 - 4.1 6.8 41.0 6 6.2 0.4 2.5 2 0 0 2 2 2 0 Mcm10 replication factor Hamartin PF04388.12 CDJ52179.1 - 4.7 5.7 36.8 7.1 5.2 36.8 1.2 1 0 0 1 1 1 0 Hamartin protein Shadoo PF14999.6 CDJ52179.1 - 7.4 6.7 16.2 13 5.9 16.2 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective E1_dh PF00676.20 CDJ52180.1 - 5.8e-82 275.0 0.0 7.2e-82 274.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 CDJ52180.1 - 0.03 13.3 0.1 0.04 12.9 0.1 1.3 1 1 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Nop53 PF07767.11 CDJ52181.1 - 0.00076 19.0 24.8 0.00086 18.8 24.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) UPF0564 PF10595.9 CDJ52181.1 - 0.0029 16.7 24.8 0.0034 16.5 24.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 RskA PF10099.9 CDJ52181.1 - 0.0037 17.6 50.1 0.14 12.4 28.8 2.5 1 1 1 2 2 2 2 Anti-sigma-K factor rskA DUF2126 PF09899.9 CDJ52181.1 - 0.017 13.3 8.9 0.016 13.3 8.9 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CAF1 PF04857.20 CDJ52181.1 - 0.036 13.2 9.0 0.04 13.1 9.0 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease SR-25 PF10500.9 CDJ52181.1 - 0.06 13.0 29.6 0.21 11.2 29.7 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein LAP1C PF05609.12 CDJ52181.1 - 0.067 12.3 23.8 0.083 12.0 23.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SID-1_RNA_chan PF13965.6 CDJ52181.1 - 0.086 11.2 6.1 0.1 11.0 6.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 CDJ52181.1 - 0.096 10.9 36.3 0.11 10.8 36.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PPP4R2 PF09184.11 CDJ52181.1 - 0.13 11.8 13.0 0.16 11.6 13.0 1.1 1 0 0 1 1 1 0 PPP4R2 SAGA-Tad1 PF12767.7 CDJ52181.1 - 0.16 11.7 17.9 0.2 11.3 17.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2052 PF09747.9 CDJ52181.1 - 0.17 12.0 19.2 0.24 11.5 19.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC27 PF09507.10 CDJ52181.1 - 0.17 11.2 35.0 0.22 10.9 35.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Neur_chan_memb PF02932.16 CDJ52181.1 - 0.2 11.7 16.1 0.27 11.3 16.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region VIR_N PF15912.5 CDJ52181.1 - 0.27 10.8 8.6 0.3 10.6 8.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4746 PF15928.5 CDJ52181.1 - 0.44 9.9 18.2 0.65 9.4 18.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RIFIN PF02009.16 CDJ52181.1 - 0.51 10.2 28.5 0.76 9.6 28.5 1.2 1 0 0 1 1 1 0 Rifin CDC45 PF02724.14 CDJ52181.1 - 0.58 8.4 17.5 0.82 7.9 17.5 1.3 1 0 0 1 1 1 0 CDC45-like protein UPF0492 PF15744.5 CDJ52181.1 - 0.59 9.3 30.1 0.65 9.2 30.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 V_ATPase_I PF01496.19 CDJ52181.1 - 0.59 8.0 20.2 0.75 7.6 20.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDK5_activator PF03261.15 CDJ52181.1 - 0.67 9.4 16.6 0.8 9.2 16.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Tom22 PF04281.13 CDJ52181.1 - 1.1 9.0 20.6 1.7 8.5 9.1 2.4 1 1 1 2 2 2 0 Mitochondrial import receptor subunit Tom22 LMBR1 PF04791.16 CDJ52181.1 - 1.7 7.4 10.6 1.8 7.4 10.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CSRNP_N PF16019.5 CDJ52181.1 - 1.9 8.4 19.8 2.6 7.9 19.8 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Hid1 PF12722.7 CDJ52181.1 - 1.9 6.5 24.5 2 6.5 24.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PA26 PF04636.13 CDJ52181.1 - 2 7.3 19.3 2.6 6.9 19.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PPL5 PF18168.1 CDJ52181.1 - 2.1 7.6 12.9 3.8 6.7 12.9 1.6 1 0 0 1 1 1 0 Prim-pol family 5 ALMT PF11744.8 CDJ52181.1 - 2.3 7.0 18.9 3.1 6.5 18.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ52181.1 - 2.3 7.1 24.5 3 6.8 24.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hamartin PF04388.12 CDJ52181.1 - 3.5 6.2 26.8 5.5 5.5 26.8 1.3 1 0 0 1 1 1 0 Hamartin protein MAJIN PF15077.6 CDJ52181.1 - 3.7 7.3 16.1 4.9 6.9 16.1 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein XAP5 PF04921.14 CDJ52181.1 - 4.8 6.9 19.6 7.8 6.2 19.6 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator GREB1 PF15782.5 CDJ52181.1 - 5 4.1 26.1 6.6 3.7 26.1 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MecA PF05389.12 CDJ52181.1 - 6.2 6.4 27.6 2.2 7.9 6.3 2.2 1 1 1 2 2 2 0 Negative regulator of genetic competence (MecA) NPR3 PF03666.13 CDJ52181.1 - 6.6 5.4 24.9 9 5.0 24.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Raftlin PF15250.6 CDJ52181.1 - 7 5.3 21.9 9.5 4.8 21.9 1.2 1 0 0 1 1 1 0 Raftlin Paramyxo_ncap PF00973.19 CDJ52181.1 - 7.8 5.3 19.1 9.6 5.0 19.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SOBP PF15279.6 CDJ52181.1 - 9 6.8 25.4 11 6.5 25.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Membralin PF09746.9 CDJ52181.1 - 9.6 5.1 15.1 12 4.8 15.1 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF4667 PF15700.5 CDJ52182.1 - 0.015 15.4 9.5 0.092 12.8 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) DUF4179 PF13786.6 CDJ52182.1 - 3.3 8.3 10.9 30 5.2 1.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) SpoIIP PF07454.11 CDJ52183.1 - 0.018 14.5 10.8 0.016 14.7 10.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 CDJ52183.1 - 0.036 14.1 8.3 0.036 14.1 8.3 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Presenilin PF01080.17 CDJ52183.1 - 0.07 11.9 12.2 0.065 12.0 12.2 1.0 1 0 0 1 1 1 0 Presenilin RPA43_OB PF17875.1 CDJ52183.1 - 0.071 13.7 10.5 0.1 13.2 10.5 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF702 PF05142.12 CDJ52183.1 - 0.13 12.7 8.8 0.16 12.5 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) EPL1 PF10513.9 CDJ52183.1 - 0.13 12.6 10.8 0.14 12.5 10.8 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like TFIIA PF03153.13 CDJ52183.1 - 0.17 11.9 32.9 0.18 11.7 32.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ52183.1 - 0.18 10.0 18.4 0.18 10.1 18.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 CDJ52183.1 - 0.23 11.2 11.0 0.24 11.2 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CDJ52183.1 - 0.25 11.5 9.9 0.25 11.5 9.9 1.1 1 0 0 1 1 1 0 DDHD domain FAM176 PF14851.6 CDJ52183.1 - 0.26 10.9 6.6 0.3 10.7 6.6 1.2 1 0 0 1 1 1 0 FAM176 family SLC12 PF03522.15 CDJ52183.1 - 0.31 10.0 8.2 0.3 10.1 8.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ52183.1 - 0.33 10.5 13.6 0.34 10.4 13.6 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4746 PF15928.5 CDJ52183.1 - 0.42 10.0 7.2 0.38 10.1 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NPR3 PF03666.13 CDJ52183.1 - 0.69 8.6 9.8 0.72 8.6 9.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MDM10 PF12519.8 CDJ52183.1 - 0.93 8.3 7.1 0.91 8.3 7.1 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF5523 PF17661.1 CDJ52183.1 - 0.94 9.1 14.7 1.1 8.9 14.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Neur_chan_memb PF02932.16 CDJ52183.1 - 1 9.4 8.6 0.99 9.4 8.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4638 PF15472.6 CDJ52183.1 - 1 9.0 8.8 1 9.0 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Pet20 PF08692.10 CDJ52183.1 - 1 10.1 4.4 1.1 9.9 4.4 1.1 1 0 0 1 1 1 0 Mitochondrial protein Pet20 CDC45 PF02724.14 CDJ52183.1 - 1 7.6 9.2 1.1 7.5 9.2 1.0 1 0 0 1 1 1 0 CDC45-like protein ABC2_membrane_2 PF12679.7 CDJ52183.1 - 1.4 8.2 4.4 1.5 8.0 4.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein OATP PF03137.20 CDJ52183.1 - 1.7 6.8 5.4 1.7 6.8 5.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Gti1_Pac2 PF09729.9 CDJ52183.1 - 1.9 8.6 9.5 2.2 8.4 9.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Sin_N PF04801.13 CDJ52183.1 - 1.9 7.6 20.6 2.1 7.5 20.6 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Sec62 PF03839.16 CDJ52183.1 - 2 7.9 7.0 2.2 7.7 7.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 CDJ52183.1 - 2 8.1 10.9 2.1 8.0 10.9 1.0 1 0 0 1 1 1 0 Connexin Zip PF02535.22 CDJ52183.1 - 2.2 7.4 5.2 2.1 7.5 5.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 CDJ52183.1 - 2.5 8.1 7.1 2.8 7.9 7.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CLN3 PF02487.17 CDJ52183.1 - 2.6 7.0 8.8 2.9 6.9 8.8 1.1 1 0 0 1 1 1 0 CLN3 protein V_ATPase_I PF01496.19 CDJ52183.1 - 2.6 5.8 15.3 2.7 5.8 15.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paf1 PF03985.13 CDJ52183.1 - 3.1 6.7 18.5 3.5 6.5 18.5 1.0 1 0 0 1 1 1 0 Paf1 ALMT PF11744.8 CDJ52183.1 - 3.2 6.5 7.2 3.2 6.5 7.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF913 PF06025.12 CDJ52183.1 - 3.5 6.5 8.4 3.8 6.4 8.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3464 PF11947.8 CDJ52183.1 - 4.1 7.1 12.9 6.4 6.5 12.9 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PPL5 PF18168.1 CDJ52183.1 - 4.3 6.5 8.3 4.7 6.4 8.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Ctr PF04145.15 CDJ52183.1 - 4.5 7.9 4.9 4.9 7.8 4.9 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF908 PF06012.12 CDJ52183.1 - 4.8 6.5 9.3 4.9 6.5 9.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) GREB1 PF15782.5 CDJ52183.1 - 8.3 3.4 11.8 8.6 3.3 11.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EIIBC-GUT_N PF03612.14 CDJ52183.1 - 8.9 6.0 11.4 13 5.5 11.4 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4647 PF15504.6 CDJ52183.1 - 9.3 5.2 15.1 10 5.1 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Slu7 PF11708.8 CDJ52184.1 - 5.6e-40 137.8 42.8 6.6e-34 117.9 42.8 2.6 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor Mitofilin PF09731.9 CDJ52184.1 - 0.016 14.0 34.6 0.036 12.9 34.6 1.7 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zf-CCHC_4 PF14392.6 CDJ52184.1 - 0.19 11.5 0.5 0.34 10.7 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle PPP4R2 PF09184.11 CDJ52184.1 - 0.65 9.5 27.2 0.22 11.1 21.6 2.1 2 0 0 2 2 2 0 PPP4R2 Dicty_REP PF05086.12 CDJ52184.1 - 3.7 5.4 14.4 6.3 4.7 14.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CRT10 PF08728.10 CDJ52184.1 - 7.3 4.6 10.5 10 4.1 10.5 1.2 1 0 0 1 1 1 0 CRT10 EI24 PF07264.11 CDJ52185.1 - 5.2e-08 33.3 4.0 0.004 17.4 1.0 2.7 2 1 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) PNISR PF15996.5 CDJ52185.1 - 0.00056 20.3 21.0 0.00056 20.3 21.0 6.7 4 1 0 4 4 4 1 Arginine/serine-rich protein PNISR DUF4667 PF15700.5 CDJ52185.1 - 0.0048 17.0 7.5 0.0048 17.0 7.5 7.1 2 2 4 6 6 6 1 Domain of unknown function (DUF4667) DUF4746 PF15928.5 CDJ52185.1 - 0.036 13.5 0.0 0.036 13.5 0.0 6.3 5 2 2 7 7 7 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 CDJ52186.1 - 0.011 15.7 27.0 0.024 14.7 27.0 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FHIPEP PF00771.20 CDJ52186.1 - 0.27 9.7 1.3 0.48 8.8 1.3 1.3 1 0 0 1 1 1 0 FHIPEP family SUIM_assoc PF16619.5 CDJ52188.1 - 0.21 11.7 0.2 0.21 11.7 0.2 4.4 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Thymidylate_kin PF02223.17 CDJ52189.1 - 0.023 14.4 1.5 0.028 14.1 1.5 1.1 1 0 0 1 1 1 0 Thymidylate kinase AF-4 PF05110.13 CDJ52189.1 - 0.059 11.5 38.0 0.072 11.2 38.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TAF4 PF05236.14 CDJ52189.1 - 0.088 12.5 15.0 0.1 12.3 15.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF1645 PF07816.11 CDJ52189.1 - 0.095 13.3 24.9 0.12 12.9 24.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) MPM1 PF17234.2 CDJ52189.1 - 0.14 12.4 18.5 0.19 12.0 18.5 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Macoilin PF09726.9 CDJ52189.1 - 0.24 9.9 27.8 0.29 9.7 27.8 1.0 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 CDJ52189.1 - 0.33 8.7 16.7 0.39 8.4 16.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BRF1 PF07741.13 CDJ52189.1 - 0.35 11.2 11.6 0.43 10.9 11.6 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain SURF6 PF04935.12 CDJ52189.1 - 0.46 10.3 17.9 0.6 9.9 17.9 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 TFIIA PF03153.13 CDJ52189.1 - 0.7 9.8 38.5 0.85 9.5 38.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LicD PF04991.13 CDJ52189.1 - 1.2 9.2 6.0 1.3 9.1 6.0 1.0 1 0 0 1 1 1 0 LicD family FCP1_C PF09309.10 CDJ52189.1 - 1.7 8.5 22.1 2.1 8.1 22.1 1.0 1 0 0 1 1 1 0 FCP1, C-terminal Roughex PF06020.11 CDJ52189.1 - 1.9 7.5 19.5 2.3 7.3 19.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Plasmodium_Vir PF05795.11 CDJ52189.1 - 2.1 7.7 19.3 2.6 7.4 19.3 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF755 PF05501.11 CDJ52189.1 - 2.2 8.6 53.1 3.7 7.9 53.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF755) Cwf_Cwc_15 PF04889.12 CDJ52189.1 - 2.4 7.8 21.2 2.9 7.6 21.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GREB1 PF15782.5 CDJ52189.1 - 2.8 5.0 28.2 3.2 4.8 28.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PepSY_TM PF03929.16 CDJ52189.1 - 2.9 7.5 6.5 3 7.4 6.5 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Glt_symporter PF03616.14 CDJ52189.1 - 3 6.4 4.7 3.4 6.3 4.7 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter eIF-3_zeta PF05091.12 CDJ52189.1 - 3.9 6.3 18.6 4.1 6.3 18.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peroxin-3 PF04882.12 CDJ52189.1 - 4 6.3 28.5 4.7 6.1 28.5 1.1 1 0 0 1 1 1 0 Peroxin-3 GTA_holin_3TM PF11351.8 CDJ52189.1 - 4.5 7.8 8.0 6.4 7.3 8.0 1.4 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Lin-8 PF03353.15 CDJ52189.1 - 4.7 6.7 29.9 5.2 6.5 29.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist UPF0524 PF15823.5 CDJ52189.1 - 5.4 6.3 15.4 6.6 6.1 15.4 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 Mcm10 PF09332.11 CDJ52189.1 - 5.5 6.3 22.6 6.6 6.1 22.6 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Menin PF05053.13 CDJ52189.1 - 5.5 5.2 20.3 6.5 5.0 20.3 1.1 1 0 0 1 1 1 0 Menin DUF4175 PF13779.6 CDJ52189.1 - 5.6 4.7 23.8 5.4 4.8 23.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDK2AP PF09806.9 CDJ52189.1 - 6.5 6.7 26.9 9 6.3 26.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein MAT1 PF06391.13 CDJ52189.1 - 7 6.4 20.5 8.7 6.1 20.5 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 NST1 PF13945.6 CDJ52189.1 - 7.2 6.7 31.0 9.6 6.3 31.0 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator PAP1 PF08601.10 CDJ52189.1 - 7.2 6.2 34.1 8.7 6.0 34.1 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 MAP65_ASE1 PF03999.12 CDJ52189.1 - 7.5 5.1 26.3 8.5 4.9 26.3 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4692 PF15763.5 CDJ52189.1 - 7.8 6.9 20.9 12 6.3 20.9 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) SLC12 PF03522.15 CDJ52189.1 - 8.4 5.3 23.4 9.4 5.1 23.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF1180 PF06679.12 CDJ52189.1 - 8.9 6.7 17.8 10 6.5 17.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF853 PF05872.12 CDJ52189.1 - 9.5 4.7 11.5 11 4.5 11.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) ALMT PF11744.8 CDJ52189.1 - 9.7 4.9 19.9 12 4.6 19.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter FHIPEP PF00771.20 CDJ52189.1 - 9.8 4.5 8.7 10 4.5 8.7 1.1 1 0 0 1 1 1 0 FHIPEP family Proteasome PF00227.26 CDJ52190.1 - 1.2e-09 38.0 0.9 1.6e-09 37.6 0.9 1.2 1 0 0 1 1 1 1 Proteasome subunit Cupin_3 PF05899.12 CDJ52190.1 - 0.13 11.9 0.0 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF4834 PF16118.5 CDJ52191.1 - 0.13 13.3 24.2 0.51 11.3 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Hamartin PF04388.12 CDJ52191.1 - 1.6 7.3 14.7 1.9 7.1 14.7 1.0 1 0 0 1 1 1 0 Hamartin protein NUDE_C PF04880.13 CDJ52191.1 - 2.6 8.5 12.4 3.4 8.1 12.4 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Peroxin-13_N PF04088.13 CDJ52191.1 - 3.1 8.0 13.2 4.7 7.5 1.2 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region MPM1 PF17234.2 CDJ52191.1 - 3.5 7.9 24.3 0.033 14.4 3.1 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Hydrolase_3 PF08282.12 CDJ52192.1 - 4.2e-05 23.4 0.1 0.0001 22.1 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ52192.1 - 0.0015 18.9 6.6 0.66 10.3 0.1 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase SUIM_assoc PF16619.5 CDJ52192.1 - 0.013 15.6 1.5 0.013 15.6 1.5 7.1 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 SARAF PF06682.12 CDJ52194.1 - 0.0027 17.4 9.1 0.0027 17.4 9.1 2.5 1 1 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis Caldesmon PF02029.15 CDJ52194.1 - 0.95 8.1 30.4 0.39 9.4 16.7 2.1 2 0 0 2 2 2 0 Caldesmon LMBR1 PF04791.16 CDJ52194.1 - 2 7.2 16.1 1.4 7.8 6.4 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein RNA_pol_Rpb1_5 PF04998.17 CDJ52195.1 - 1.7e-100 335.8 0.2 2.5e-100 335.3 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CDJ52195.1 - 9.5e-75 250.4 0.0 2.3e-74 249.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CDJ52195.1 - 3.8e-48 163.9 4.3 6.3e-48 163.1 4.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CDJ52195.1 - 1.6e-44 151.2 2.1 1.8e-44 151.0 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 CDJ52195.1 - 1.6e-39 134.1 0.2 1.6e-39 134.1 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.18 CDJ52195.1 - 1.3e-29 103.2 0.0 4.5e-15 55.9 0.0 2.8 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 3 Secretin_N_2 PF07655.13 CDJ52195.1 - 0.093 13.3 2.7 0.25 11.9 2.7 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain VirE1 PF12189.8 CDJ52195.1 - 0.11 12.6 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Single-strand DNA-binding protein RNA_pol_Rpb1_1 PF04997.12 CDJ52196.1 - 3.2e-83 279.6 0.0 4e-83 279.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 DUF4266 PF14086.6 CDJ52196.1 - 0.49 11.4 7.4 1.2 10.2 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) LSM PF01423.22 CDJ52197.1 - 8.9e-16 57.3 0.4 1.3e-15 56.9 0.4 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDJ52197.1 - 0.053 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 CDJ52197.1 - 0.095 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Acetyltransf_5 PF13444.6 CDJ52199.1 - 0.073 13.8 0.9 0.086 13.6 0.9 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4407 PF14362.6 CDJ52199.1 - 1.1 8.5 18.5 1.3 8.3 18.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KAsynt_C_assoc PF16197.5 CDJ52199.1 - 1.3 9.5 7.6 1.6 9.2 7.6 1.1 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Spc7 PF08317.11 CDJ52199.1 - 2.9 6.7 24.7 3.3 6.5 24.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF702 PF05142.12 CDJ52199.1 - 3.5 8.1 13.9 4.5 7.7 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) EPL1 PF10513.9 CDJ52199.1 - 6.1 7.2 13.8 8.1 6.8 13.8 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Hydin_ADK PF17213.3 CDJ52199.1 - 7.3 6.8 13.6 9.9 6.4 13.6 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Baculo_PP31 PF05311.11 CDJ52199.1 - 8.8 5.7 15.5 9.4 5.6 15.5 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RskA PF10099.9 CDJ52200.1 - 0.0077 16.5 22.7 0.011 16.0 22.7 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF92 PF01940.16 CDJ52200.1 - 0.021 14.3 0.6 0.025 14.0 0.6 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF92 NEMP PF10225.9 CDJ52200.1 - 0.21 11.2 7.0 0.23 11.1 7.0 1.1 1 0 0 1 1 1 0 NEMP family SID-1_RNA_chan PF13965.6 CDJ52200.1 - 0.21 9.9 4.8 0.21 9.9 4.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BAF1_ABF1 PF04684.13 CDJ52200.1 - 0.34 9.9 16.5 0.38 9.7 16.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Paf1 PF03985.13 CDJ52200.1 - 0.34 9.9 14.5 0.37 9.7 14.5 1.2 1 0 0 1 1 1 0 Paf1 FHIPEP PF00771.20 CDJ52200.1 - 0.37 9.2 13.7 0.41 9.1 13.7 1.0 1 0 0 1 1 1 0 FHIPEP family FAM91_C PF14648.6 CDJ52200.1 - 0.45 9.3 9.6 0.47 9.2 9.6 1.1 1 0 0 1 1 1 0 FAM91 C-terminus eIF-3_zeta PF05091.12 CDJ52200.1 - 0.46 9.4 20.2 0.49 9.3 20.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ52200.1 - 0.55 8.1 14.5 0.54 8.1 14.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Serinc PF03348.15 CDJ52200.1 - 0.64 8.9 9.5 0.68 8.8 9.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF572 PF04502.13 CDJ52200.1 - 0.78 9.3 18.5 0.87 9.1 18.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) MCR_alpha PF02249.17 CDJ52200.1 - 0.78 10.2 6.7 0.5 10.8 5.2 1.4 1 1 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Oleosin PF01277.17 CDJ52200.1 - 0.98 9.2 4.5 1.3 8.8 4.5 1.3 1 0 0 1 1 1 0 Oleosin OATP PF03137.20 CDJ52200.1 - 0.99 7.6 7.9 0.91 7.7 7.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2232 PF09991.9 CDJ52200.1 - 1.1 8.4 7.7 1.2 8.2 7.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) IHABP4_N PF16174.5 CDJ52200.1 - 1.1 9.8 23.6 1.5 9.4 23.6 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DDHD PF02862.17 CDJ52200.1 - 1.2 9.3 17.5 1.4 9.0 17.5 1.1 1 0 0 1 1 1 0 DDHD domain R_equi_Vir PF05526.11 CDJ52200.1 - 1.3 8.9 12.2 1.4 8.7 12.2 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein PEX11 PF05648.14 CDJ52200.1 - 1.5 8.3 12.6 1.2 8.6 11.9 1.3 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Presenilin PF01080.17 CDJ52200.1 - 1.8 7.3 20.6 2 7.1 20.6 1.0 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ52200.1 - 2 8.3 13.4 2.4 8.1 13.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CLN3 PF02487.17 CDJ52200.1 - 2.7 6.9 13.3 2.1 7.3 12.5 1.3 1 1 0 1 1 1 0 CLN3 protein RBP_receptor PF14752.6 CDJ52200.1 - 2.8 6.4 12.5 3.6 6.0 12.5 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor SART-1 PF03343.13 CDJ52200.1 - 2.8 6.4 22.2 3.2 6.2 22.2 1.0 1 0 0 1 1 1 0 SART-1 family DUF1980 PF09323.10 CDJ52200.1 - 3.3 7.6 11.9 3.4 7.6 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RR_TM4-6 PF06459.12 CDJ52200.1 - 4.3 7.1 18.8 5.4 6.8 18.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 THOC2_N PF16134.5 CDJ52200.1 - 4.5 5.8 17.0 5.4 5.5 17.0 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus PigN PF04987.14 CDJ52200.1 - 5.6 5.7 7.4 5.6 5.7 7.4 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Peptidase_S15 PF02129.18 CDJ52200.1 - 5.8 6.4 15.0 7.8 6.0 15.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Neur_chan_memb PF02932.16 CDJ52200.1 - 5.9 6.9 12.8 6.6 6.7 12.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ52200.1 - 6 6.7 46.7 7 6.5 46.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 CDJ52200.1 - 6.3 6.7 17.1 6.9 6.5 17.1 1.0 1 0 0 1 1 1 0 Velvet factor O-antigen_lig PF13425.6 CDJ52200.1 - 6.7 5.4 5.3 6.6 5.4 5.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Bestrophin PF01062.21 CDJ52200.1 - 7.1 5.9 10.8 7.8 5.8 10.8 1.0 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Ribosomal_60s PF00428.19 CDJ52200.1 - 8.1 7.1 23.4 5.1 7.8 19.3 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein UQ_con PF00179.26 CDJ52201.1 - 1.2e-13 50.9 0.1 3.4e-12 46.2 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme UBA PF00627.31 CDJ52201.1 - 1.4e-06 28.0 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Ribosomal_60s PF00428.19 CDJ52201.1 - 0.71 10.5 13.6 0.24 12.0 10.8 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Activator_LAG-3 PF11498.8 CDJ52203.1 - 0.0045 16.0 13.3 0.0045 16.0 13.3 2.6 2 0 0 2 2 2 1 Transcriptional activator LAG-3 Nitroreductase PF00881.24 CDJ52203.1 - 0.41 10.7 10.7 0.47 10.5 5.5 2.2 2 0 0 2 2 2 0 Nitroreductase family UCR_14kD PF02271.16 CDJ52204.1 - 7.5e-15 54.7 0.0 1.1e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit PAPS_reduct PF01507.19 CDJ52204.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Rsm22 PF09243.10 CDJ52205.1 - 1.2e-08 34.6 0.2 1.2e-08 34.6 0.2 2.1 2 0 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 TFIIA PF03153.13 CDJ52205.1 - 0.00015 21.9 17.1 0.00015 21.9 17.1 2.5 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 CDJ52205.1 - 1.2 8.9 21.5 0.19 11.6 1.8 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term eIF-3_zeta PF05091.12 CDJ52205.1 - 2.1 7.2 25.4 0.41 9.6 9.7 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4746 PF15928.5 CDJ52205.1 - 4.2 6.7 14.2 3.2 7.1 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) UPF0560 PF10577.9 CDJ52205.1 - 4.2 5.8 42.7 0.14 10.6 10.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 DUF4471 PF14740.6 CDJ52205.1 - 5.5 6.1 11.5 7.2 5.7 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) CLN3 PF02487.17 CDJ52205.1 - 8.5 5.3 12.3 9.8 5.1 1.9 2.4 2 0 0 2 2 2 0 CLN3 protein PdaC PF13739.6 CDJ52205.1 - 9.9 7.2 6.8 15 6.7 1.4 2.5 2 0 0 2 2 2 0 Deacetylase PdaC Ribosomal_60s PF00428.19 CDJ52206.1 - 0.00071 20.1 10.5 0.00071 20.1 10.5 9.6 6 2 2 8 8 8 2 60s Acidic ribosomal protein RskA PF10099.9 CDJ52206.1 - 0.0053 17.1 1.1 0.0053 17.1 1.1 9.8 4 3 4 8 8 8 1 Anti-sigma-K factor rskA UPF0542 PF15086.6 CDJ52206.1 - 0.047 13.6 9.5 0.26 11.3 0.0 4.3 3 1 1 4 4 4 0 Uncharacterised protein family UPF0542 CENP-L PF13092.6 CDJ52206.1 - 0.85 9.8 8.3 5.8 7.1 0.2 3.5 3 0 0 3 3 3 0 Kinetochore complex Sim4 subunit Fta1 TPT PF03151.16 CDJ52207.1 - 1.9e-50 171.9 11.1 6.2e-29 101.3 1.2 3.7 4 0 0 4 4 4 3 Triose-phosphate Transporter family EamA PF00892.20 CDJ52207.1 - 0.0041 17.3 3.8 0.0041 17.3 3.8 3.5 4 1 0 4 4 4 1 EamA-like transporter family DUF2207 PF09972.9 CDJ52207.1 - 0.15 10.8 2.1 3.3 6.4 0.0 3.5 3 1 1 4 4 4 0 Predicted membrane protein (DUF2207) RskA PF10099.9 CDJ52207.1 - 0.76 10.1 0.0 0.24 11.7 5.1 7.1 4 2 3 7 7 7 0 Anti-sigma-K factor rskA TMEM132D_C PF15706.5 CDJ52207.1 - 2.6 7.9 13.6 0.29 11.0 1.5 3.9 3 1 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF2417 PF10329.9 CDJ52207.1 - 6.2 6.2 6.5 6.6 6.1 0.2 3.5 3 0 0 3 3 3 0 Region of unknown function (DUF2417) SUIM_assoc PF16619.5 CDJ52208.1 - 0.00015 21.7 17.0 0.0084 16.2 3.6 2.8 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ52208.1 - 0.046 13.3 19.2 0.07 12.7 4.7 2.3 2 0 0 2 2 2 0 Spt20 family ACDC PF14733.6 CDJ52208.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.3 3 0 0 3 3 3 0 AP2-coincident C-terminal HTH_37 PF13744.6 CDJ52211.1 - 0.14 12.1 0.3 19 5.3 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Spt20 PF12090.8 CDJ52213.1 - 0.0046 16.6 9.4 0.0072 16.0 9.4 1.3 1 0 0 1 1 1 1 Spt20 family DUF1635 PF07795.11 CDJ52213.1 - 0.023 14.6 2.7 0.023 14.6 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) SPX PF03105.19 CDJ52213.1 - 1.6 8.5 8.2 2.4 8.0 8.2 1.2 1 0 0 1 1 1 0 SPX domain NEMP PF10225.9 CDJ52213.1 - 2.2 7.9 6.2 2.9 7.5 5.4 1.5 1 1 0 1 1 1 0 NEMP family Roughex PF06020.11 CDJ52213.1 - 3.6 6.6 6.2 5 6.1 6.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein TERB2 PF15101.6 CDJ52213.1 - 4.9 7.1 9.8 1.5 8.8 6.9 1.6 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF973 PF06157.11 CDJ52213.1 - 8.9 5.3 5.5 12 4.8 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Spc7_N PF15402.6 CDJ52215.1 - 0.11 10.8 20.3 0.13 10.5 20.3 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 SLC12 PF03522.15 CDJ52215.1 - 0.26 10.3 13.8 0.29 10.1 13.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Draxin PF15550.6 CDJ52215.1 - 0.94 9.3 15.2 1.1 9.0 15.2 1.2 1 0 0 1 1 1 0 Draxin Plasmodium_Vir PF05795.11 CDJ52215.1 - 2.2 7.6 7.6 2.6 7.4 7.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.12 CDJ52215.1 - 2.5 7.0 20.8 3.9 6.3 20.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SUIM_assoc PF16619.5 CDJ52216.1 - 0.00029 20.8 0.1 0.00029 20.8 0.1 9.9 3 3 2 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 PI3K_1B_p101 PF10486.9 CDJ52216.1 - 0.00038 18.4 9.2 0.00038 18.4 9.2 2.6 2 1 0 2 2 2 2 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SRP68 PF16969.5 CDJ52217.1 - 6.9e-25 88.1 22.6 9.4e-13 48.0 4.3 2.0 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 Peptidase_S49_N PF08496.10 CDJ52218.1 - 0.049 13.7 3.8 0.076 13.1 3.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TFIIA PF03153.13 CDJ52218.1 - 0.069 13.1 33.9 0.088 12.8 33.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CDJ52218.1 - 0.14 11.1 31.7 0.24 10.3 31.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 UPF0560 PF10577.9 CDJ52218.1 - 0.2 10.1 13.2 0.29 9.6 13.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Neur_chan_memb PF02932.16 CDJ52218.1 - 0.52 10.3 9.1 0.61 10.1 9.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 CDJ52218.1 - 1.9 6.6 19.5 2.2 6.4 19.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3568 PF12092.8 CDJ52220.1 - 0.093 12.8 7.1 0.11 12.6 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) FHIPEP PF00771.20 CDJ52220.1 - 0.18 10.3 5.4 0.19 10.2 5.4 1.0 1 0 0 1 1 1 0 FHIPEP family SelP_N PF04592.14 CDJ52220.1 - 0.3 10.4 13.2 0.31 10.4 13.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Aminotran_1_2 PF00155.21 CDJ52220.1 - 0.91 8.6 8.0 1.1 8.4 8.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II CD20 PF04103.15 CDJ52220.1 - 2.4 8.2 5.4 6 6.9 5.4 1.7 1 1 0 1 1 1 0 CD20-like family Coilin_N PF15862.5 CDJ52220.1 - 2.5 7.9 12.5 2.8 7.8 12.5 1.2 1 0 0 1 1 1 0 Coilin N-terminus Cyclin_C PF02984.19 CDJ52220.1 - 3.1 7.9 11.8 3.7 7.7 11.8 1.1 1 0 0 1 1 1 0 Cyclin, C-terminal domain HemX PF04375.14 CDJ52220.1 - 6.3 6.0 25.7 7.2 5.8 25.7 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase N6_N4_Mtase PF01555.18 CDJ52221.1 - 0.0021 17.8 0.7 2.3e+02 1.3 0.3 5.2 3 2 0 3 3 3 0 DNA methylase Activator_LAG-3 PF11498.8 CDJ52222.1 - 0.0017 17.4 19.8 0.0017 17.4 19.8 6.0 4 2 1 5 5 5 1 Transcriptional activator LAG-3 CAC1F_C PF16885.5 CDJ52223.1 - 0.00056 19.7 15.3 0.00072 19.3 15.3 1.0 1 0 0 1 1 1 1 Voltage-gated calcium channel subunit alpha, C-term GREB1 PF15782.5 CDJ52223.1 - 0.0065 13.7 36.3 0.0078 13.4 36.3 1.0 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer AAA_11 PF13086.6 CDJ52223.1 - 0.01 15.7 25.0 0.012 15.4 25.0 1.1 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 CDJ52223.1 - 0.056 13.3 28.1 0.081 12.7 28.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Plasmodium_Vir PF05795.11 CDJ52223.1 - 0.085 12.3 19.2 0.14 11.6 19.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LAP1C PF05609.12 CDJ52223.1 - 0.16 11.0 30.7 0.2 10.7 30.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Sec62 PF03839.16 CDJ52223.1 - 0.67 9.4 25.3 2.6 7.5 25.3 1.8 1 1 0 1 1 1 0 Translocation protein Sec62 ALMT PF11744.8 CDJ52223.1 - 1.2 7.8 29.3 1.9 7.2 29.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SMYLE_N PF18615.1 CDJ52223.1 - 2 7.9 26.3 2.7 7.4 26.3 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PA26 PF04636.13 CDJ52223.1 - 3 6.7 29.9 4.3 6.1 29.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ndc1_Nup PF09531.10 CDJ52223.1 - 3 6.4 29.2 4.1 6.0 29.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2052 PF09747.9 CDJ52223.1 - 3.4 7.7 31.3 4.6 7.3 31.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SR-25 PF10500.9 CDJ52223.1 - 4.4 6.8 54.4 1.7 8.2 17.4 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 CDJ52223.1 - 6.7 5.1 43.9 8.7 4.8 43.9 1.1 1 0 0 1 1 1 0 Macoilin family Raftlin PF15250.6 CDJ52223.1 - 8.8 5.0 30.7 11 4.6 30.7 1.1 1 0 0 1 1 1 0 Raftlin RskA PF10099.9 CDJ52224.1 - 0.0028 18.0 14.7 0.0028 18.0 14.7 3.8 2 1 1 3 3 3 1 Anti-sigma-K factor rskA NuA4 PF09340.10 CDJ52224.1 - 2 8.4 5.6 2 8.3 1.8 2.7 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF1818 PF08848.11 CDJ52224.1 - 3.2 7.9 8.9 2.7 8.1 4.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) YABBY PF04690.13 CDJ52225.1 - 0.0047 17.5 7.0 0.0047 17.5 7.0 2.8 2 1 0 2 2 1 1 YABBY protein SUIM_assoc PF16619.5 CDJ52225.1 - 0.015 15.3 5.7 0.015 15.3 5.7 6.3 3 2 2 5 5 4 0 Unstructured region C-term to UIM in Ataxin3 DUF908 PF06012.12 CDJ52225.1 - 0.23 10.9 14.3 0.45 9.9 7.3 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Cytochrom_B_N_2 PF13631.6 CDJ52225.1 - 0.26 11.3 0.5 0.64 10.0 0.0 1.9 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Neur_chan_memb PF02932.16 CDJ52225.1 - 0.77 9.8 13.3 0.67 10.0 6.3 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S64 PF08192.11 CDJ52225.1 - 1.1 7.7 10.0 0.78 8.2 6.2 2.0 2 0 0 2 2 2 0 Peptidase family S64 SpoIIIAH PF12685.7 CDJ52225.1 - 1.7 8.5 0.0 1.7 8.5 0.0 2.8 2 1 0 2 2 1 0 SpoIIIAH-like protein DUF2140 PF09911.9 CDJ52225.1 - 2 7.9 10.6 0.31 10.5 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF2072 PF09845.9 CDJ52225.1 - 3.7 7.8 9.6 5.2 7.3 5.0 2.4 2 0 0 2 2 2 0 Zn-ribbon containing protein FAM176 PF14851.6 CDJ52225.1 - 5.5 6.6 10.2 4.4 7.0 2.2 2.7 2 1 0 2 2 2 0 FAM176 family DUF4366 PF14283.6 CDJ52225.1 - 5.6 7.0 13.8 0.21 11.6 3.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) OATP PF03137.20 CDJ52225.1 - 5.9 5.1 8.9 5.2 5.2 0.3 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family BUD22 PF09073.10 CDJ52227.1 - 0.025 14.0 0.0 0.025 14.0 0.0 5.4 3 1 1 5 5 5 0 BUD22 DUF2722 PF10846.8 CDJ52230.1 - 0.00016 20.8 2.5 0.00016 20.8 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Drf_FH1 PF06346.12 CDJ52230.1 - 0.00049 19.8 34.8 0.00063 19.5 34.8 1.1 1 0 0 1 1 1 1 Formin Homology Region 1 Spt20 PF12090.8 CDJ52230.1 - 0.029 14.0 16.5 0.038 13.6 16.5 1.1 1 0 0 1 1 1 0 Spt20 family NST1 PF13945.6 CDJ52230.1 - 0.088 12.9 6.2 0.12 12.5 6.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator EIF4E-T PF10477.9 CDJ52230.1 - 0.36 9.6 5.5 0.42 9.4 5.5 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4834 PF16118.5 CDJ52230.1 - 1.7 9.6 5.4 2.4 9.2 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Menin PF05053.13 CDJ52230.1 - 2.6 6.3 6.4 4.3 5.6 6.4 1.3 1 0 0 1 1 1 0 Menin Conotoxin PF02950.17 CDJ52230.1 - 3.8 8.6 5.2 3.8 8.6 3.9 1.6 1 1 0 1 1 1 0 Conotoxin Presenilin PF01080.17 CDJ52231.1 - 0.00013 20.9 26.4 0.00014 20.7 26.4 1.0 1 0 0 1 1 1 1 Presenilin Nop14 PF04147.12 CDJ52231.1 - 0.00038 18.8 22.7 0.00046 18.6 22.7 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 CDJ52231.1 - 0.0014 17.0 20.0 0.0015 16.9 20.0 1.2 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 CDJ52231.1 - 0.0015 18.0 20.0 0.0018 17.8 20.0 1.2 1 0 0 1 1 1 1 SDA1 DDHD PF02862.17 CDJ52231.1 - 0.0045 17.2 18.6 0.0062 16.7 18.6 1.3 1 0 0 1 1 1 1 DDHD domain Nha1_C PF08619.10 CDJ52231.1 - 0.0089 15.3 26.3 0.011 15.0 26.3 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Neur_chan_memb PF02932.16 CDJ52231.1 - 0.009 16.1 21.5 0.01 15.9 21.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PNISR PF15996.5 CDJ52231.1 - 0.019 15.2 32.8 0.022 15.0 32.8 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Caldesmon PF02029.15 CDJ52231.1 - 0.027 13.2 35.1 0.029 13.1 35.1 1.1 1 0 0 1 1 1 0 Caldesmon DUF913 PF06025.12 CDJ52231.1 - 0.029 13.4 14.0 0.038 13.0 14.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 CDJ52231.1 - 0.031 13.1 25.7 0.039 12.8 25.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 CDJ52231.1 - 0.042 12.7 14.4 0.047 12.6 14.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Velvet PF11754.8 CDJ52231.1 - 0.059 13.3 18.9 0.096 12.6 18.9 1.4 1 0 0 1 1 1 0 Velvet factor PAT1 PF09770.9 CDJ52231.1 - 0.062 11.6 39.0 0.067 11.5 39.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.11 CDJ52231.1 - 0.074 11.5 16.7 0.082 11.4 16.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.13 CDJ52231.1 - 0.079 12.9 51.5 0.12 12.4 51.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLC12 PF03522.15 CDJ52231.1 - 0.19 10.7 27.8 0.22 10.5 27.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4045 PF13254.6 CDJ52231.1 - 0.2 11.2 24.7 0.25 11.0 24.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF5427 PF10310.9 CDJ52231.1 - 0.26 10.2 31.5 0.34 9.8 31.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PA26 PF04636.13 CDJ52231.1 - 0.31 9.9 20.4 0.36 9.7 20.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Dapper PF15268.6 CDJ52231.1 - 0.43 9.4 29.2 0.47 9.2 29.2 1.0 1 0 0 1 1 1 0 Dapper Vfa1 PF08432.10 CDJ52231.1 - 0.45 10.8 33.3 0.66 10.3 33.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Rrn6 PF10214.9 CDJ52231.1 - 0.5 8.8 26.4 0.61 8.5 26.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FAM60A PF15396.6 CDJ52231.1 - 0.52 10.3 24.6 0.69 9.9 24.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CAC1F_C PF16885.5 CDJ52231.1 - 0.54 9.9 18.3 0.77 9.4 18.3 1.3 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Membralin PF09746.9 CDJ52231.1 - 0.66 8.9 20.0 1 8.3 20.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein DUF2052 PF09747.9 CDJ52231.1 - 0.8 9.8 33.5 1.4 9.0 33.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pkinase_fungal PF17667.1 CDJ52231.1 - 0.89 8.3 13.2 1 8.1 13.2 1.1 1 0 0 1 1 1 0 Fungal protein kinase Lin-8 PF03353.15 CDJ52231.1 - 1 8.9 32.9 1.3 8.5 32.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LAP1C PF05609.12 CDJ52231.1 - 1 8.4 27.6 1.2 8.1 27.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CSG2 PF16965.5 CDJ52231.1 - 1.1 8.2 12.8 1.5 7.7 12.8 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator AAA_11 PF13086.6 CDJ52231.1 - 1.1 9.0 26.1 1.4 8.6 26.1 1.2 1 0 0 1 1 1 0 AAA domain DUF2151 PF10221.9 CDJ52231.1 - 1.2 7.7 18.6 1.4 7.5 18.6 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator SAPS PF04499.15 CDJ52231.1 - 1.2 7.9 23.6 1.4 7.6 23.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ALMT PF11744.8 CDJ52231.1 - 1.2 7.8 21.1 1.6 7.4 21.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF5523 PF17661.1 CDJ52231.1 - 1.8 8.2 34.6 3 7.4 34.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Raftlin PF15250.6 CDJ52231.1 - 2.3 6.9 25.2 2.7 6.6 25.2 1.1 1 0 0 1 1 1 0 Raftlin DUF4569 PF15133.6 CDJ52231.1 - 2.8 7.6 29.1 4.3 7.0 29.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Ndc1_Nup PF09531.10 CDJ52231.1 - 2.9 6.5 17.6 3.2 6.3 17.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MCM_bind PF09739.9 CDJ52231.1 - 3 6.2 26.1 4 5.8 26.1 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Endostatin PF06482.11 CDJ52231.1 - 3.1 7.2 25.4 4.4 6.7 25.4 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Trypan_PARP PF05887.11 CDJ52231.1 - 3.3 7.7 9.9 4.5 7.3 9.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glyco_transf_41 PF13844.6 CDJ52231.1 - 3.6 5.9 12.2 3.8 5.8 12.2 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 DUF4050 PF13259.6 CDJ52231.1 - 6.7 7.0 29.9 10 6.4 29.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Hamartin PF04388.12 CDJ52231.1 - 7.3 5.1 28.0 8.2 5.0 28.0 1.0 1 0 0 1 1 1 0 Hamartin protein Rtf2 PF04641.12 CDJ52231.1 - 7.7 5.8 27.2 13 5.0 27.2 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Paf1 PF03985.13 CDJ52231.1 - 7.8 5.4 44.4 10 5.0 44.4 1.1 1 0 0 1 1 1 0 Paf1 HCO3_cotransp PF00955.21 CDJ52231.1 - 8.1 5.1 11.3 10 4.8 11.3 1.2 1 0 0 1 1 1 0 HCO3- transporter family PPP4R2 PF09184.11 CDJ52231.1 - 8.9 5.8 26.6 12 5.4 26.6 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 CDJ52232.1 - 0.013 15.5 32.7 0.015 15.3 32.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 CDJ52232.1 - 0.18 11.1 35.6 0.25 10.7 35.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SLC12 PF03522.15 CDJ52232.1 - 0.43 9.6 11.6 0.5 9.3 11.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Gcd10p PF04189.13 CDJ52234.1 - 1e-19 70.8 0.2 6.3e-17 61.6 0.4 2.2 2 0 0 2 2 2 2 Gcd10p family CDK2AP PF09806.9 CDJ52234.1 - 5.7 6.9 20.4 5.8 6.9 2.1 3.4 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein ADK PF00406.22 CDJ52235.1 - 3.6e-05 23.9 2.0 0.05 13.7 0.3 3.2 1 1 2 3 3 3 1 Adenylate kinase KTI12 PF08433.10 CDJ52235.1 - 0.00059 19.4 0.0 0.00059 19.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 RskA PF10099.9 CDJ52235.1 - 0.0017 18.7 12.2 0.0029 17.9 10.4 2.0 2 0 0 2 2 2 1 Anti-sigma-K factor rskA AAA_18 PF13238.6 CDJ52235.1 - 0.0025 18.4 0.0 0.0043 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CDJ52235.1 - 0.0064 16.9 0.1 0.38 11.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDJ52235.1 - 0.0067 15.8 0.0 0.0067 15.8 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CDJ52235.1 - 0.015 15.7 0.1 0.094 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Spt20 PF12090.8 CDJ52235.1 - 0.055 13.1 12.1 0.5 10.0 0.3 2.1 2 0 0 2 2 2 0 Spt20 family AAA_33 PF13671.6 CDJ52235.1 - 0.073 13.2 0.0 0.073 13.2 0.0 1.9 3 0 0 3 3 3 0 AAA domain Shadoo PF14999.6 CDJ52235.1 - 0.43 10.7 15.0 0.78 9.8 15.0 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective SUIM_assoc PF16619.5 CDJ52235.1 - 0.73 9.9 26.6 0.29 11.2 7.5 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 CDJ52236.1 - 0.0013 18.8 2.0 0.0013 18.8 2.0 5.0 3 2 1 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 CDJ52236.1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ52236.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF3446 PF11928.8 CDJ52236.1 - 0.018 15.4 13.7 0.08 13.3 13.7 2.2 1 0 0 1 1 1 0 Early growth response N-terminal domain IMUP PF15761.5 CDJ52236.1 - 1.1 10.0 11.2 5 7.9 11.2 2.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF1645 PF07816.11 CDJ52236.1 - 1.9 9.0 12.3 0.076 13.6 4.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) TFIIA PF03153.13 CDJ52236.1 - 5.4 6.9 45.1 0.014 15.4 5.6 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 CDJ52236.1 - 9.5 4.4 5.7 12 4.0 5.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PDZ_6 PF17820.1 CDJ52237.1 - 2.3e-05 24.1 0.0 0.00011 22.0 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 CDJ52237.1 - 0.00043 20.6 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ52237.1 - 0.028 14.7 0.1 0.09 13.1 0.1 1.8 1 0 0 1 1 1 0 PDZ domain PAP2 PF01569.21 CDJ52238.1 - 4.4e-20 71.8 0.4 4.4e-20 71.8 0.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily EarP PF10093.9 CDJ52238.1 - 0.01 14.9 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP PAP2_C PF14360.6 CDJ52238.1 - 0.029 14.9 2.9 0.81 10.3 0.2 3.3 3 0 0 3 3 3 0 PAP2 superfamily C-terminal PAP2 PF01569.21 CDJ52239.1 - 6.6e-18 64.8 18.0 5.1e-17 61.9 14.7 3.4 2 1 0 2 2 2 1 PAP2 superfamily FAM176 PF14851.6 CDJ52239.1 - 9.5e-07 28.6 8.5 0.012 15.3 0.0 3.7 3 0 0 3 3 3 2 FAM176 family 7tm_1 PF00001.21 CDJ52239.1 - 9.7e-05 21.8 0.3 0.0037 16.6 0.1 2.6 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) SUIM_assoc PF16619.5 CDJ52239.1 - 0.00013 21.9 0.0 0.00013 21.9 0.0 6.2 5 3 0 5 5 3 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ52239.1 - 0.0013 18.4 2.6 0.0013 18.4 2.6 4.5 4 0 0 4 4 4 2 Spt20 family DUF2722 PF10846.8 CDJ52239.1 - 0.0013 17.7 2.9 0.0013 17.7 2.9 4.7 4 1 0 4 4 3 1 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ52239.1 - 0.015 16.3 0.2 0.015 16.3 0.2 5.1 5 1 0 5 5 4 0 Domain of unknown function (DUF4834) PigN PF04987.14 CDJ52239.1 - 0.019 13.9 6.2 0.062 12.2 0.1 3.2 3 0 0 3 3 3 0 Phosphatidylinositolglycan class N (PIG-N) DUF898 PF05987.13 CDJ52239.1 - 0.023 13.7 0.2 0.18 10.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) O-antigen_lig PF13425.6 CDJ52239.1 - 0.047 12.5 0.0 2 7.1 0.0 2.2 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Phage_Gp23 PF10669.9 CDJ52239.1 - 0.13 12.6 1.3 14 6.1 0.0 3.3 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) Apt1 PF10351.9 CDJ52239.1 - 0.13 11.0 16.1 0.32 9.8 1.5 3.1 2 1 0 2 2 2 0 Golgi-body localisation protein domain FHIPEP PF00771.20 CDJ52239.1 - 0.17 10.3 9.2 0.91 7.9 0.1 2.8 3 0 0 3 3 3 0 FHIPEP family PAP2_3 PF14378.6 CDJ52239.1 - 0.26 11.0 8.3 8.5 6.0 4.0 3.4 3 1 0 3 3 3 0 PAP2 superfamily DUF3169 PF11368.8 CDJ52239.1 - 0.26 10.7 1.3 0.96 8.9 0.0 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3169) DUF1449 PF07290.11 CDJ52239.1 - 0.27 10.9 2.3 5.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) Dpy19 PF10034.9 CDJ52239.1 - 0.3 9.2 1.3 0.97 7.6 0.1 2.0 2 0 0 2 2 2 0 Q-cell neuroblast polarisation OSTbeta PF15048.6 CDJ52239.1 - 0.47 10.6 0.0 0.47 10.6 0.0 2.6 3 0 0 3 3 3 0 Organic solute transporter subunit beta protein SCF PF02404.15 CDJ52239.1 - 0.5 9.6 0.0 0.5 9.6 0.0 2.0 2 0 0 2 2 1 0 Stem cell factor Connexin PF00029.19 CDJ52239.1 - 0.53 10.0 11.0 0.58 9.9 0.0 3.7 3 1 1 4 4 4 0 Connexin SpoIIIAH PF12685.7 CDJ52239.1 - 1.8 8.3 18.3 2.9 7.7 0.8 3.3 2 1 0 2 2 2 0 SpoIIIAH-like protein Arv1 PF04161.13 CDJ52239.1 - 2.9 8.0 4.2 11 6.1 0.1 2.6 2 1 0 2 2 2 0 Arv1-like family DUF3464 PF11947.8 CDJ52239.1 - 3.8 7.2 0.0 3.8 7.2 0.0 3.7 4 0 0 4 4 3 0 Photosynthesis affected mutant 68 FxsA PF04186.13 CDJ52239.1 - 4.2 7.6 7.7 14 5.9 0.3 3.7 3 0 0 3 3 3 0 FxsA cytoplasmic membrane protein Ctr PF04145.15 CDJ52239.1 - 6.5 7.4 25.3 12 6.4 6.5 4.4 2 2 0 2 2 1 0 Ctr copper transporter family TssO PF17561.2 CDJ52239.1 - 9.3 6.3 16.2 0.71 10.0 0.5 2.7 3 0 0 3 3 2 0 Type VI secretion system, TssO DUF2722 PF10846.8 CDJ52240.1 - 0.1 11.5 8.6 0.094 11.6 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ52240.1 - 0.33 9.7 1.8 0.3 9.8 1.8 1.2 1 0 0 1 1 1 0 Presenilin Nitroreductase PF00881.24 CDJ52240.1 - 0.35 10.9 9.6 0.47 10.5 9.6 1.1 1 0 0 1 1 1 0 Nitroreductase family BatD PF13584.6 CDJ52240.1 - 0.55 9.0 9.7 0.62 8.8 9.7 1.0 1 0 0 1 1 1 0 Oxygen tolerance CemA PF03040.14 CDJ52240.1 - 0.62 10.0 2.8 0.82 9.6 2.8 1.1 1 0 0 1 1 1 0 CemA family DUF3138 PF11336.8 CDJ52240.1 - 0.65 8.5 13.2 0.95 8.0 13.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) UPF0560 PF10577.9 CDJ52240.1 - 4.7 5.6 7.9 4.9 5.5 7.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SIR2 PF02146.17 CDJ52242.1 - 7.8e-07 29.2 0.0 7.8e-07 29.2 0.0 3.7 4 1 1 5 5 5 1 Sir2 family DUF2076 PF09849.9 CDJ52242.1 - 0.0004 20.5 6.9 0.0004 20.5 6.9 9.0 6 3 3 9 9 9 2 Uncharacterized protein conserved in bacteria (DUF2076) Macoilin PF09726.9 CDJ52242.1 - 0.0016 17.1 22.2 0.0016 17.1 22.2 5.2 5 0 0 5 5 5 3 Macoilin family RNA_pol_A_bac PF01000.26 CDJ52243.1 - 8.6e-17 61.5 0.0 1.4e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain GMP_synt_C PF00958.22 CDJ52244.1 - 8.7e-26 89.8 0.0 1.6e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain TFIIA PF03153.13 CDJ52244.1 - 0.00024 21.2 24.3 0.00029 20.9 24.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ52244.1 - 0.0026 16.2 19.7 0.0035 15.7 19.7 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Connexin PF00029.19 CDJ52244.1 - 0.0061 16.3 4.9 0.0086 15.9 4.9 1.1 1 0 0 1 1 1 1 Connexin Pex14_N PF04695.13 CDJ52244.1 - 0.0062 17.2 15.8 0.0099 16.5 15.8 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.16 CDJ52244.1 - 0.012 15.7 2.2 0.015 15.4 2.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 CDJ52244.1 - 0.02 13.8 2.8 0.026 13.5 2.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3405 PF11885.8 CDJ52244.1 - 0.023 13.3 4.0 0.029 13.0 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) NPR3 PF03666.13 CDJ52244.1 - 0.027 13.3 7.3 0.036 12.9 7.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 CDJ52244.1 - 0.033 14.3 4.5 0.046 13.9 4.5 1.2 1 0 0 1 1 1 0 DDHD domain DUF4011 PF13195.6 CDJ52244.1 - 0.036 14.0 0.1 0.042 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) CLN3 PF02487.17 CDJ52244.1 - 0.068 12.2 5.2 0.091 11.8 5.2 1.1 1 0 0 1 1 1 0 CLN3 protein Kei1 PF08552.11 CDJ52244.1 - 0.068 13.0 1.2 0.1 12.5 1.2 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 HCO3_cotransp PF00955.21 CDJ52244.1 - 0.075 11.8 1.5 0.098 11.5 1.5 1.1 1 0 0 1 1 1 0 HCO3- transporter family SpoIIP PF07454.11 CDJ52244.1 - 0.1 12.1 12.7 0.13 11.7 12.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EOS1 PF12326.8 CDJ52244.1 - 0.12 12.3 1.8 0.18 11.7 1.8 1.3 1 0 0 1 1 1 0 N-glycosylation protein PBP1_TM PF14812.6 CDJ52244.1 - 0.14 12.5 3.6 0.24 11.8 3.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ndc1_Nup PF09531.10 CDJ52244.1 - 0.15 10.7 5.7 0.2 10.3 5.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peroxin-13_N PF04088.13 CDJ52244.1 - 0.15 12.3 2.9 0.27 11.5 2.9 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Suf PF05843.14 CDJ52244.1 - 0.15 12.0 11.4 0.24 11.3 11.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ52244.1 - 0.19 10.5 14.5 0.26 10.0 14.5 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 CDJ52244.1 - 0.24 10.4 3.2 0.32 9.9 3.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Folliculin PF11704.8 CDJ52244.1 - 0.38 10.6 6.2 0.6 10.0 6.2 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport PIP5K PF01504.18 CDJ52244.1 - 0.42 9.8 8.9 0.59 9.3 8.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Zip PF02535.22 CDJ52244.1 - 0.61 9.2 3.2 1 8.5 2.9 1.4 2 0 0 2 2 2 0 ZIP Zinc transporter CCDC53 PF10152.9 CDJ52244.1 - 0.74 10.2 11.9 1.1 9.6 11.9 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex LMBR1 PF04791.16 CDJ52244.1 - 0.85 8.5 3.9 1 8.2 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GTA_holin_3TM PF11351.8 CDJ52244.1 - 0.9 10.1 7.1 2.1 8.9 7.1 1.6 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Tim54 PF11711.8 CDJ52244.1 - 0.97 8.2 11.7 1.4 7.6 11.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CSG2 PF16965.5 CDJ52244.1 - 1.1 8.2 3.2 1.4 7.8 3.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator EMC3_TMCO1 PF01956.16 CDJ52244.1 - 1.3 8.8 11.7 1.9 8.2 11.7 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like OATP PF03137.20 CDJ52244.1 - 1.3 7.2 4.5 1.8 6.7 4.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Sec62 PF03839.16 CDJ52244.1 - 1.4 8.3 10.8 2.1 7.8 10.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PepSY_TM PF03929.16 CDJ52244.1 - 1.8 8.2 4.3 2.5 7.7 4.3 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DUF3292 PF11696.8 CDJ52244.1 - 2.7 6.2 7.5 3.7 5.8 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF1980 PF09323.10 CDJ52244.1 - 2.8 7.8 6.7 4.3 7.2 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Peptidase_U57 PF05582.12 CDJ52244.1 - 3.2 6.9 8.2 4.5 6.4 8.2 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Ureide_permease PF07168.11 CDJ52244.1 - 4.9 5.8 6.1 8.3 5.1 6.1 1.3 1 0 0 1 1 1 0 Ureide permease VIR_N PF15912.5 CDJ52244.1 - 5.7 6.4 8.6 7.7 6.0 8.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4770 PF15994.5 CDJ52244.1 - 5.9 7.1 15.6 9.1 6.5 15.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) AIF_C PF14721.6 CDJ52244.1 - 6 7.2 10.4 10 6.5 10.4 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3408 PF11888.8 CDJ52244.1 - 7 6.8 15.2 11 6.1 15.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) BORG_CEP PF14957.6 CDJ52244.1 - 9.1 7.5 11.0 15 6.8 11.0 1.3 1 0 0 1 1 1 0 Cdc42 effector Ydr279_N PF17745.1 CDJ52245.1 - 0.0084 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain Nrap_D4 PF17405.2 CDJ52246.1 - 2.3e-24 85.9 0.2 2.3e-24 85.9 0.2 1.9 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 CDJ52246.1 - 2.1e-19 70.1 0.0 1.4e-17 64.2 0.0 3.5 3 1 0 3 3 3 1 Nrap protein domain 3 Nrap_D5 PF17406.2 CDJ52246.1 - 4.8e-14 52.4 6.4 8.9e-14 51.6 0.0 3.7 3 1 1 4 4 4 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 CDJ52246.1 - 5.5e-14 52.5 1.7 1.1e-09 38.6 1.4 3.3 2 1 0 2 2 2 2 Nrap protein domain 1 Nrap_D2 PF17403.2 CDJ52246.1 - 4.6e-13 49.2 0.1 4.9e-06 26.4 0.0 3.5 3 0 0 3 3 3 2 Nrap protein PAP/OAS-like domain RskA PF10099.9 CDJ52246.1 - 0.0054 17.1 12.9 0.0054 17.1 12.9 4.1 4 0 0 4 4 4 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ52246.1 - 0.0082 15.8 2.8 0.015 14.9 2.8 1.3 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ52246.1 - 0.038 12.9 1.1 0.061 12.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ52246.1 - 0.1 12.7 6.5 0.31 11.1 6.5 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ank_2 PF12796.7 CDJ52248.1 - 3.7e-37 126.8 0.0 7.1e-15 55.4 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ52248.1 - 3.6e-26 91.2 2.3 1.2e-14 54.4 0.1 5.5 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ52248.1 - 4.2e-26 88.1 3.0 7.6e-06 25.9 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CDJ52248.1 - 5.3e-26 89.9 9.1 1.5e-06 28.3 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CDJ52248.1 - 1.2e-22 79.7 0.2 3.9e-07 30.2 0.0 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) TPH PF13868.6 CDJ52250.1 - 2.7e-44 151.1 151.1 2.7e-44 151.1 151.1 2.4 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain RPAP2_Rtr1 PF04181.13 CDJ52251.1 - 3e-07 30.7 1.8 3e-07 30.7 1.8 2.6 2 0 0 2 2 2 1 Rtr1/RPAP2 family Cpn10 PF00166.21 CDJ52252.1 - 1e-16 60.7 0.0 1.4e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cas_csx3 PF09620.10 CDJ52252.1 - 0.08 12.8 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) ThiF PF00899.21 CDJ52253.1 - 2.6e-46 158.0 0.1 4.1e-46 157.3 0.1 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CDJ52253.1 - 0.00018 21.8 0.1 0.53 10.6 0.0 2.6 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CDJ52253.1 - 0.0049 17.3 0.2 0.025 15.0 0.2 2.0 1 1 0 1 1 1 1 Putative NAD(P)-binding Arm PF00514.23 CDJ52254.1 - 5.1e-07 29.5 11.9 0.31 11.1 0.0 9.6 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDJ52254.1 - 0.00077 19.8 12.8 0.017 15.5 0.1 6.2 4 1 1 5 5 5 2 HEAT repeats FPL PF09758.9 CDJ52254.1 - 0.17 11.9 0.0 12 5.9 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised conserved protein TSP9 PF11493.8 CDJ52255.1 - 0.014 16.1 0.1 0.068 13.8 0.1 2.3 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 DUF2076 PF09849.9 CDJ52255.1 - 4.6 7.2 9.0 1.7 8.6 5.7 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) AAA PF00004.29 CDJ52256.1 - 6.8e-43 146.3 0.0 4.9e-35 120.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ52256.1 - 1.4e-07 32.0 5.6 0.009 16.4 0.2 4.4 3 1 1 4 4 4 2 AAA ATPase domain AAA_lid_3 PF17862.1 CDJ52256.1 - 4.5e-07 29.6 0.0 0.026 14.3 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain PEX-1N PF09262.11 CDJ52256.1 - 5.4e-07 29.9 1.1 9.8e-07 29.1 0.2 1.9 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal IstB_IS21 PF01695.17 CDJ52256.1 - 1.6e-05 24.7 0.1 0.00053 19.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Rad17 PF03215.15 CDJ52256.1 - 0.00095 19.1 0.4 1.5 8.7 0.2 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_33 PF13671.6 CDJ52256.1 - 0.0031 17.7 0.0 0.027 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CDJ52256.1 - 0.0042 17.1 0.8 0.34 10.9 0.4 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 CDJ52256.1 - 0.015 15.3 0.0 0.047 13.7 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 CDJ52256.1 - 0.016 15.5 6.2 1.2 9.4 0.1 4.2 3 2 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 CDJ52256.1 - 0.03 14.7 0.0 8.7 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase 7TMR-HDED PF07697.11 CDJ52256.1 - 0.036 14.2 0.8 2.1 8.4 0.1 2.7 2 0 0 2 2 2 0 7TM-HD extracellular RuvB_N PF05496.12 CDJ52256.1 - 0.21 11.3 0.0 0.82 9.4 0.1 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ACBP PF00887.19 CDJ52257.1 - 7.7e-05 22.8 1.9 0.00032 20.9 1.9 2.1 1 0 0 1 1 1 1 Acyl CoA binding protein Tam41_Mmp37 PF09139.11 CDJ52258.1 - 2.4e-54 185.0 0.0 2.5e-53 181.6 0.0 2.3 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial TrbE PF11100.8 CDJ52259.1 - 0.088 13.0 1.8 0.31 11.3 1.8 1.9 1 0 0 1 1 1 0 Conjugal transfer protein TrbE DUF1180 PF06679.12 CDJ52259.1 - 0.15 12.5 7.3 0.14 12.6 5.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DDHD PF02862.17 CDJ52262.1 - 0.041 14.0 3.6 0.049 13.8 3.6 1.2 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ52262.1 - 0.073 12.0 6.3 0.073 12.0 6.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ52262.1 - 0.15 12.0 24.2 0.16 12.0 24.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.10 CDJ52262.1 - 0.19 11.8 8.3 0.25 11.4 8.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Suf PF05843.14 CDJ52262.1 - 0.34 10.8 9.2 0.42 10.5 9.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.7 CDJ52262.1 - 0.5 8.4 6.5 0.51 8.4 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 CDJ52262.1 - 0.74 9.8 5.0 0.83 9.7 5.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Roughex PF06020.11 CDJ52262.1 - 0.96 8.5 10.9 1.2 8.1 10.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein FAM222A PF15258.6 CDJ52262.1 - 1 8.4 21.1 1.1 8.3 21.1 1.0 1 0 0 1 1 1 0 Protein family of FAM222A DUF3292 PF11696.8 CDJ52262.1 - 1.2 7.4 7.8 1.5 7.1 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Pex14_N PF04695.13 CDJ52262.1 - 1.5 9.5 16.7 2 9.0 16.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2464 PF10240.9 CDJ52262.1 - 2.3 7.7 6.0 2.6 7.5 6.0 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 DUF4484 PF14831.6 CDJ52262.1 - 3.1 7.8 9.3 4.4 7.3 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) RR_TM4-6 PF06459.12 CDJ52262.1 - 3.4 7.4 8.2 4.2 7.1 8.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ52262.1 - 5 5.8 12.8 6.1 5.5 12.8 1.0 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 CDJ52262.1 - 6.3 5.7 4.6 7.7 5.5 4.6 1.1 1 0 0 1 1 1 0 CLN3 protein RskA PF10099.9 CDJ52263.1 - 0.00052 20.4 7.7 0.0092 16.3 8.3 10.8 3 3 4 8 8 8 3 Anti-sigma-K factor rskA ESM4 PF15952.5 CDJ52263.1 - 0.0024 18.3 13.7 0.0024 18.3 13.7 8.0 4 1 1 7 7 7 2 Enhancer of split M4 family AAA_23 PF13476.6 CDJ52263.1 - 0.0033 18.0 18.0 0.0033 18.0 18.0 6.4 5 1 0 6 6 6 1 AAA domain SUIM_assoc PF16619.5 CDJ52263.1 - 0.0035 17.4 8.2 0.0035 17.4 8.2 17.8 7 5 2 9 9 9 1 Unstructured region C-term to UIM in Ataxin3 Pex14_N PF04695.13 CDJ52263.1 - 0.011 16.4 20.5 0.011 16.4 20.5 10.5 4 1 5 9 9 9 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sas10_Utp3 PF04000.15 CDJ52263.1 - 0.05 14.2 0.0 0.05 14.2 0.0 6.2 8 1 0 8 8 8 0 Sas10/Utp3/C1D family SWIB PF02201.18 CDJ52264.1 - 8.9e-17 60.7 0.0 2.2e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain Spt20 PF12090.8 CDJ52264.1 - 0.0051 16.5 29.7 0.0051 16.5 29.7 5.7 4 2 1 5 5 5 2 Spt20 family PP2C PF00481.21 CDJ52265.1 - 1.7e-31 109.8 0.1 7e-30 104.5 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ52265.1 - 0.00012 21.8 0.5 0.014 15.0 0.5 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PRC2_HTH_1 PF18118.1 CDJ52265.1 - 0.028 15.2 0.4 0.044 14.6 0.4 1.3 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Presenilin PF01080.17 CDJ52265.1 - 0.27 10.0 0.2 0.31 9.8 0.2 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ52265.1 - 0.3 11.0 12.8 0.38 10.7 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ52265.1 - 0.3 12.1 3.8 0.54 11.3 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ52265.1 - 0.43 9.5 13.7 0.56 9.1 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52265.1 - 0.52 9.9 18.0 0.65 9.6 18.0 1.1 1 0 0 1 1 1 0 Spt20 family DUF4175 PF13779.6 CDJ52265.1 - 1.7 6.4 14.1 2.2 6.1 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UPF0560 PF10577.9 CDJ52265.1 - 7.9 4.8 7.9 9.6 4.6 7.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SPX PF03105.19 CDJ52266.1 - 0.014 15.4 20.9 0.019 14.9 20.9 1.3 1 0 0 1 1 1 0 SPX domain RIFIN PF02009.16 CDJ52266.1 - 0.23 11.3 1.0 0.3 10.9 1.0 1.1 1 0 0 1 1 1 0 Rifin MAP70 PF07058.11 CDJ52266.1 - 0.55 8.9 12.6 0.7 8.6 12.6 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 Miga PF10265.9 CDJ52266.1 - 0.65 8.9 16.2 0.86 8.5 16.2 1.1 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 CDJ52266.1 - 0.67 8.7 21.3 0.89 8.3 21.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribosomal_60s PF00428.19 CDJ52266.1 - 0.96 10.1 7.8 1.7 9.3 7.8 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Presenilin PF01080.17 CDJ52266.1 - 3.7 6.2 10.9 4.8 5.8 10.9 1.2 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 CDJ52266.1 - 4.3 6.4 31.5 5.3 6.1 31.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Tmemb_cc2 PF10267.9 CDJ52266.1 - 5.6 6.0 10.8 6.8 5.7 10.8 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF572 PF04502.13 CDJ52266.1 - 5.9 6.4 11.3 6.6 6.3 11.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PPP4R2 PF09184.11 CDJ52266.1 - 7.2 6.1 13.3 9.1 5.8 13.3 1.1 1 0 0 1 1 1 0 PPP4R2 P3A PF08727.11 CDJ52267.1 - 0.066 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Poliovirus 3A protein like IMUP PF15761.5 CDJ52267.1 - 1.4 9.7 8.5 3.6 8.3 8.5 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ52268.1 - 0.0031 17.1 35.0 0.0031 17.1 35.0 10.1 6 3 0 9 9 9 3 Nuclear RNA-splicing-associated protein Galactosyl_T PF01762.21 CDJ52269.1 - 5.7e-30 104.6 0.0 1.2e-29 103.6 0.0 1.5 1 0 0 1 1 1 1 Galactosyltransferase DUF2722 PF10846.8 CDJ52270.1 - 0.0058 15.6 14.1 0.0058 15.6 14.1 7.1 4 2 2 6 6 6 2 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ52270.1 - 0.044 13.8 0.0 0.044 13.8 0.0 10.3 5 4 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 CDJ52271.1 - 4.4e-41 141.0 0.0 4.4e-41 141.0 0.0 4.1 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ52271.1 - 4e-21 75.5 0.0 4e-21 75.5 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Mo-nitro_C PF06967.11 CDJ52271.1 - 0.059 13.3 0.4 0.16 11.9 0.4 1.7 1 0 0 1 1 1 0 Mo-dependent nitrogenase C-terminus Pkinase_fungal PF17667.1 CDJ52271.1 - 0.096 11.4 0.0 0.096 11.4 0.0 5.9 3 2 2 5 5 5 0 Fungal protein kinase E1-E2_ATPase PF00122.20 CDJ52272.1 - 5e-17 62.0 1.3 6.1e-14 52.0 0.4 2.5 2 0 0 2 2 2 2 E1-E2 ATPase SARAF PF06682.12 CDJ52272.1 - 0.006 16.3 15.5 0.006 16.3 15.5 2.0 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis GREB1 PF15782.5 CDJ52272.1 - 0.074 10.2 16.3 0.12 9.5 16.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ribosomal_60s PF00428.19 CDJ52272.1 - 0.31 11.7 21.6 3.1 8.4 5.2 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Macoilin PF09726.9 CDJ52272.1 - 1.3 7.5 13.2 2.6 6.5 13.2 1.5 1 0 0 1 1 1 0 Macoilin family TP53IP5 PF15331.6 CDJ52272.1 - 1.9 8.6 12.8 4.3 7.4 12.8 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 LMBR1 PF04791.16 CDJ52272.1 - 3 6.6 4.8 3.7 6.4 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF908 PF06012.12 CDJ52272.1 - 3.2 7.1 19.9 0.012 15.1 9.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Zip PF02535.22 CDJ52272.1 - 3.9 6.6 11.6 6 6.0 11.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SAGA-Tad1 PF12767.7 CDJ52272.1 - 5.9 6.6 26.6 0.38 10.5 18.9 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit MDM10 PF12519.8 CDJ52272.1 - 6.1 5.6 13.1 9.2 5.0 13.1 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Hydrolase PF00702.26 CDJ52273.1 - 0.15 12.3 8.9 0.48 10.7 8.9 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RskA PF10099.9 CDJ52273.1 - 0.41 10.9 34.3 0.26 11.6 19.5 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Hydrolase PF00702.26 CDJ52274.1 - 2.3e-06 28.1 9.7 3.7e-05 24.1 9.7 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ52274.1 - 0.0011 19.0 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Secretin_N_2 PF07655.13 CDJ52274.1 - 2 9.0 13.6 0.29 11.7 6.3 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain SR-25 PF10500.9 CDJ52274.1 - 4.3 6.9 37.4 4 7.0 7.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ52274.1 - 7.9 5.2 9.9 14 4.4 9.9 1.5 1 1 0 1 1 1 0 Golgi-body localisation protein domain Fra10Ac1 PF09725.9 CDJ52276.1 - 3.5e-12 46.5 16.3 2e-10 40.8 10.1 3.4 2 1 0 2 2 2 2 Folate-sensitive fragile site protein Fra10Ac1 TMEM65 PF10507.9 CDJ52277.1 - 2.9e-36 123.7 3.8 2.9e-36 123.7 3.8 4.9 5 0 0 5 5 5 1 Transmembrane protein 65 GAF PF01590.26 CDJ52277.1 - 3.8e-13 50.2 0.5 3.2e-12 47.2 0.0 2.5 3 0 0 3 3 3 1 GAF domain Ribosomal_60s PF00428.19 CDJ52277.1 - 0.0036 17.8 4.3 0.0036 17.8 4.3 8.4 4 3 2 6 6 6 2 60s Acidic ribosomal protein Cwf_Cwc_15 PF04889.12 CDJ52277.1 - 0.051 13.3 30.0 0.81 9.4 5.6 3.4 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 CDJ52277.1 - 0.15 11.4 32.6 0.77 9.0 18.0 2.8 2 1 0 2 2 2 0 BUD22 Apt1 PF10351.9 CDJ52277.1 - 0.16 10.8 31.7 0.017 14.0 8.9 3.3 3 0 0 3 3 3 0 Golgi-body localisation protein domain SAPS PF04499.15 CDJ52277.1 - 0.65 8.7 15.6 0.79 8.4 5.4 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 CDJ52277.1 - 9.3 4.9 37.7 0.022 13.5 10.7 2.8 3 0 0 3 3 3 0 Presenilin CitMHS PF03600.16 CDJ52278.1 - 0.0003 20.1 2.1 0.00048 19.4 2.1 1.2 1 0 0 1 1 1 1 Citrate transporter RskA PF10099.9 CDJ52279.1 - 0.0037 17.6 22.4 0.0037 17.6 22.4 10.9 4 1 2 7 7 7 3 Anti-sigma-K factor rskA CobT PF06213.12 CDJ52281.1 - 0.41 10.0 32.5 0.44 9.9 32.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 CDJ52281.1 - 0.77 8.9 13.3 0.8 8.9 13.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.8 CDJ52281.1 - 0.81 8.4 22.5 0.87 8.3 22.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 STAC2_u1 PF16664.5 CDJ52281.1 - 0.86 10.1 19.0 0.96 9.9 19.0 1.0 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Connexin PF00029.19 CDJ52281.1 - 1.2 8.9 18.8 1.2 8.9 18.8 1.1 1 0 0 1 1 1 0 Connexin FAM76 PF16046.5 CDJ52281.1 - 1.5 8.1 26.3 1.7 7.9 26.3 1.0 1 0 0 1 1 1 0 FAM76 protein CPSF100_C PF13299.6 CDJ52281.1 - 1.5 9.0 19.4 2 8.6 19.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CLN3 PF02487.17 CDJ52281.1 - 1.6 7.7 20.1 1.6 7.7 20.1 1.0 1 0 0 1 1 1 0 CLN3 protein RR_TM4-6 PF06459.12 CDJ52281.1 - 1.8 8.3 26.5 2 8.2 26.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.13 CDJ52281.1 - 1.9 9.1 32.9 2.3 8.9 32.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rtf2 PF04641.12 CDJ52281.1 - 1.9 7.8 19.8 2.1 7.7 19.8 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger RPN2_C PF18004.1 CDJ52281.1 - 2 8.3 21.1 2.4 8.1 21.1 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain ASC PF00858.24 CDJ52281.1 - 2.3 7.1 16.5 2.6 6.9 16.5 1.0 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel SpoIIP PF07454.11 CDJ52281.1 - 2.4 7.5 26.3 2.7 7.4 26.3 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PBP1_TM PF14812.6 CDJ52281.1 - 2.4 8.6 10.5 3.1 8.2 10.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 CDJ52281.1 - 2.5 7.9 15.5 3 7.6 15.5 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF5308 PF17233.2 CDJ52281.1 - 2.9 8.1 20.0 3.4 7.9 20.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF913 PF06025.12 CDJ52281.1 - 2.9 6.8 16.8 2.9 6.8 16.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 CDJ52281.1 - 3 6.0 22.1 3.4 5.9 22.1 1.0 1 0 0 1 1 1 0 CDC45-like protein V_ATPase_I PF01496.19 CDJ52281.1 - 3.5 5.4 26.6 3.5 5.4 26.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5523 PF17661.1 CDJ52281.1 - 3.5 7.2 24.4 4.5 6.9 24.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) MMU163 PF17119.5 CDJ52281.1 - 4.6 6.3 11.2 5.1 6.2 11.2 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Cellulose_synt PF03552.14 CDJ52281.1 - 4.8 5.6 13.3 4.8 5.6 13.3 1.0 1 0 0 1 1 1 0 Cellulose synthase Afi1 PF07792.12 CDJ52281.1 - 4.8 7.7 22.6 5.6 7.4 22.6 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 CDJ52281.1 - 4.9 5.8 30.4 5.6 5.6 30.4 1.0 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 CDJ52281.1 - 5.1 5.9 23.3 5.8 5.7 23.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_pol_Rpc4 PF05132.14 CDJ52281.1 - 5.7 7.4 20.9 6.8 7.1 20.9 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 PIP5K PF01504.18 CDJ52281.1 - 5.8 6.1 19.9 5.9 6.0 19.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DREPP PF05558.12 CDJ52281.1 - 6 6.7 10.1 7 6.5 10.1 1.0 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide SelP_N PF04592.14 CDJ52281.1 - 6.1 6.2 30.6 7 6.0 30.6 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PPL5 PF18168.1 CDJ52281.1 - 6.6 5.9 18.6 6.9 5.9 18.6 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Gti1_Pac2 PF09729.9 CDJ52281.1 - 6.7 6.8 22.7 8.2 6.5 22.7 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family Zip PF02535.22 CDJ52281.1 - 6.9 5.8 20.2 7.5 5.7 20.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 CDJ52281.1 - 7.4 4.8 14.9 7.2 4.9 14.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF740 PF05340.12 CDJ52281.1 - 8 5.1 13.4 8.6 5.0 13.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF2072 PF09845.9 CDJ52281.1 - 8 6.7 17.5 10 6.4 17.5 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF2828 PF11443.8 CDJ52281.1 - 8.2 4.4 23.7 8.8 4.3 23.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4045 PF13254.6 CDJ52281.1 - 9 5.8 21.7 10 5.7 21.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) MDM10 PF12519.8 CDJ52281.1 - 9.1 5.0 21.8 9.2 5.0 21.8 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PTPRCAP PF15713.5 CDJ52281.1 - 9.3 6.5 29.7 12 6.2 29.7 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CCSAP PF15748.5 CDJ52281.1 - 9.4 6.3 28.9 10 6.2 28.9 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CSG2 PF16965.5 CDJ52281.1 - 9.6 5.0 14.8 10 4.9 14.8 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2052 PF09747.9 CDJ52281.1 - 9.9 6.2 26.6 12 6.0 26.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NPR3 PF03666.13 CDJ52281.1 - 9.9 4.8 25.1 11 4.6 25.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SR-25 PF10500.9 CDJ52282.1 - 0.00014 21.6 37.6 0.0049 16.5 15.2 2.7 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 CDJ52282.1 - 0.0045 16.7 2.0 0.0045 16.7 2.0 2.6 3 0 0 3 3 3 2 Coiled-coil domain-containing protein 106 DUF3915 PF13054.6 CDJ52282.1 - 0.04 13.9 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF4228 PF14009.6 CDJ52282.1 - 0.14 12.5 8.7 0.72 10.2 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) HA2 PF04408.23 CDJ52282.1 - 0.2 12.0 3.0 1.3 9.3 0.5 2.8 2 1 0 2 2 2 0 Helicase associated domain (HA2) FTZ PF03867.14 CDJ52282.1 - 1.1 8.8 11.0 7 6.1 5.7 2.4 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region Presenilin PF01080.17 CDJ52282.1 - 2.7 6.7 10.5 2.3 6.9 3.0 2.1 2 0 0 2 2 2 0 Presenilin Mitofilin PF09731.9 CDJ52284.1 - 1 8.2 32.1 1.2e+02 1.2 32.1 2.1 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Presenilin PF01080.17 CDJ52284.1 - 1.3 7.7 15.8 0.2 10.4 7.1 2.3 2 0 0 2 2 2 0 Presenilin Apt1 PF10351.9 CDJ52284.1 - 7.3 5.3 15.8 1.6 7.5 12.3 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain Cwf_Cwc_15 PF04889.12 CDJ52284.1 - 8.9 6.0 12.4 0.82 9.4 4.9 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Utp14 PF04615.13 CDJ52285.1 - 2.6e-05 23.0 2.3 2.6e-05 23.0 2.3 2.8 2 1 0 2 2 2 1 Utp14 protein Spt20 PF12090.8 CDJ52285.1 - 4.3e-05 23.3 36.0 0.0004 20.1 10.1 8.1 5 2 1 6 6 6 3 Spt20 family DUF5345 PF17280.2 CDJ52285.1 - 0.0099 15.8 0.5 0.0099 15.8 0.5 6.6 6 0 0 6 6 6 1 Family of unknown function (DUF5345) SUIM_assoc PF16619.5 CDJ52285.1 - 0.013 15.6 0.7 0.013 15.6 0.7 13.0 9 3 1 10 10 10 0 Unstructured region C-term to UIM in Ataxin3 SPRY PF00622.28 CDJ52285.1 - 0.029 14.5 0.0 0.029 14.5 0.0 3.3 4 0 0 4 4 4 0 SPRY domain Dala_Dala_lig_N PF01820.21 CDJ52285.1 - 4.3 7.9 5.5 60 4.2 0.0 3.8 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus Med15 PF09606.10 CDJ52286.1 - 8 5.0 98.8 0.0074 15.0 6.1 3.3 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Rad21_Rec8 PF04824.16 CDJ52287.1 - 0.00059 19.1 0.4 0.002 17.4 0.4 2.0 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF4179 PF13786.6 CDJ52287.1 - 0.9 10.1 0.0 0.9 10.1 0.0 11.4 9 5 1 10 10 10 0 Domain of unknown function (DUF4179) Methyltr_RsmB-F PF01189.17 CDJ52288.1 - 1.6e-18 67.1 7.3 2.6e-11 43.5 0.4 4.4 3 1 1 4 4 4 4 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 CDJ52288.1 - 0.00016 21.5 3.7 0.11 12.3 0.1 3.2 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ52288.1 - 0.0057 17.3 0.3 0.64 10.7 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain ADH_zinc_N PF00107.26 CDJ52288.1 - 0.011 15.7 0.5 0.72 9.8 0.5 2.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 CDJ52288.1 - 0.018 15.8 5.4 0.089 13.5 0.1 3.8 3 1 0 4 4 4 0 Methyltransferase domain FtsJ PF01728.19 CDJ52288.1 - 0.073 13.2 7.6 2.2 8.4 3.9 3.0 1 1 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CDJ52288.1 - 1.1 9.1 9.2 1.7 8.4 0.0 3.2 2 1 0 2 2 2 0 Methyltransferase domain Spt20 PF12090.8 CDJ52290.1 - 0.028 14.1 24.9 0.039 13.6 24.9 1.2 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ52290.1 - 0.12 11.4 12.1 0.14 11.3 12.1 1.0 1 0 0 1 1 1 0 Drosophila roughex protein DivIC PF04977.15 CDJ52290.1 - 0.14 11.9 12.8 0.19 11.5 12.8 1.1 1 0 0 1 1 1 0 Septum formation initiator MPM1 PF17234.2 CDJ52290.1 - 0.2 11.9 13.5 0.24 11.6 13.5 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 TFIIA PF03153.13 CDJ52290.1 - 0.22 11.5 22.5 0.24 11.4 22.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 CDJ52290.1 - 0.28 10.6 12.4 0.29 10.5 12.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM76 PF16046.5 CDJ52290.1 - 0.28 10.5 15.6 0.28 10.5 15.6 1.0 1 0 0 1 1 1 0 FAM76 protein UPF0524 PF15823.5 CDJ52290.1 - 0.54 9.6 13.3 0.6 9.5 13.3 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 DUF702 PF05142.12 CDJ52290.1 - 0.56 10.7 10.0 0.77 10.2 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Lin-8 PF03353.15 CDJ52290.1 - 0.71 9.4 20.7 0.8 9.2 20.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4407 PF14362.6 CDJ52290.1 - 0.74 9.1 5.3 0.74 9.1 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 CDJ52290.1 - 0.89 8.0 23.6 1.1 7.7 23.6 1.0 1 0 0 1 1 1 0 Macoilin family DUF4718 PF15842.5 CDJ52290.1 - 1.2 8.9 14.5 1.6 8.5 14.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) PI3K_1B_p101 PF10486.9 CDJ52290.1 - 1.2 6.8 15.5 1.4 6.6 15.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SPX PF03105.19 CDJ52290.1 - 1.3 8.9 21.8 1.5 8.7 21.8 1.0 1 0 0 1 1 1 0 SPX domain RRP14 PF15459.6 CDJ52290.1 - 2.3 8.9 12.9 0.59 10.8 9.7 1.6 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 NST1 PF13945.6 CDJ52290.1 - 2.4 8.2 22.2 3 7.9 22.2 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator MAGE PF01454.19 CDJ52290.1 - 2.8 7.6 11.0 3.4 7.3 11.0 1.2 1 0 0 1 1 1 0 MAGE family baeRF_family10 PF18854.1 CDJ52290.1 - 3 8.1 7.0 3.9 7.7 7.0 1.1 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 DUF4175 PF13779.6 CDJ52290.1 - 4.3 5.1 16.1 4.5 5.1 16.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GREB1 PF15782.5 CDJ52290.1 - 5.2 4.1 18.2 5.5 4.0 18.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RAP1 PF07218.11 CDJ52290.1 - 5.2 5.2 15.1 5.3 5.2 15.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.9 CDJ52290.1 - 5.9 5.0 16.2 6.3 4.9 16.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FCP1_C PF09309.10 CDJ52290.1 - 6.7 6.5 18.7 8.2 6.2 18.7 1.0 1 0 0 1 1 1 0 FCP1, C-terminal Agouti PF05039.12 CDJ52290.1 - 7.2 7.4 11.8 3.2 8.5 8.9 1.7 1 1 1 2 2 2 0 Agouti protein CCDC24 PF15669.5 CDJ52290.1 - 7.9 6.3 15.3 11 5.8 15.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family PNISR PF15996.5 CDJ52290.1 - 9.1 6.5 21.2 11 6.2 21.2 1.0 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF908 PF06012.12 CDJ52290.1 - 9.5 5.5 19.8 11 5.3 19.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) RuvX PF03652.15 CDJ52291.1 - 0.0047 17.3 2.4 6.7 7.1 0.1 3.4 3 1 0 3 3 3 2 Holliday junction resolvase Adeno_PIX PF03955.14 CDJ52291.1 - 1.6 8.9 9.5 4 7.7 1.6 2.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Pex2_Pex12 PF04757.14 CDJ52292.1 - 4.3e-20 72.3 9.3 3.8e-19 69.2 9.2 2.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region Presenilin PF01080.17 CDJ52292.1 - 0.00099 18.0 7.8 0.00099 18.0 7.8 2.9 3 0 0 3 3 3 2 Presenilin DUF2722 PF10846.8 CDJ52292.1 - 0.0018 17.3 6.6 0.0018 17.3 6.6 6.2 5 1 1 6 6 6 2 Protein of unknown function (DUF2722) zf-RING_5 PF14634.6 CDJ52292.1 - 0.55 10.2 6.6 0.22 11.5 3.0 2.2 1 1 1 2 2 2 0 zinc-RING finger domain ASC PF00858.24 CDJ52292.1 - 0.97 8.3 9.8 4 6.3 1.6 2.3 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel zf-C3HC4 PF00097.25 CDJ52292.1 - 1.1 9.2 6.2 2.8 7.9 6.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ52292.1 - 4.7 7.1 9.6 18 5.3 9.6 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BAF1_ABF1 PF04684.13 CDJ52292.1 - 8.5 5.3 37.7 0.097 11.7 8.1 3.1 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor Ribosomal_60s PF00428.19 CDJ52293.1 - 4 8.1 11.8 5.8 7.6 11.8 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4179 PF13786.6 CDJ52294.1 - 0.072 13.6 0.4 0.072 13.6 0.4 5.4 4 1 1 5 5 5 0 Domain of unknown function (DUF4179) Sporozoite_P67 PF05642.11 CDJ52294.1 - 0.46 8.5 17.8 0.016 13.3 12.0 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen TFIIA PF03153.13 CDJ52295.1 - 0.00034 20.7 10.3 0.00034 20.7 10.3 1.5 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cons_hypoth698 PF03601.14 CDJ52295.1 - 0.12 11.3 5.9 0.21 10.4 5.9 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 698 Sterile PF03015.19 CDJ52296.1 - 0.096 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein AFG1_ATPase PF03969.16 CDJ52296.1 - 0.2 10.5 0.1 0.22 10.4 0.1 1.3 1 1 0 1 1 1 0 AFG1-like ATPase AFG1_ATPase PF03969.16 CDJ52297.1 - 1.7e-11 43.7 0.0 1.7e-11 43.7 0.0 2.6 2 1 0 2 2 2 1 AFG1-like ATPase Med15 PF09606.10 CDJ52297.1 - 0.0061 15.3 25.0 0.007 15.1 25.0 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.9 CDJ52297.1 - 0.024 13.0 15.4 0.022 13.1 15.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PepSY_TM PF03929.16 CDJ52297.1 - 0.035 13.8 2.9 0.05 13.3 2.9 1.2 1 0 0 1 1 1 0 PepSY-associated TM region DUF4175 PF13779.6 CDJ52297.1 - 0.83 7.5 27.5 1.1 7.1 27.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Activator_LAG-3 PF11498.8 CDJ52297.1 - 1 8.3 51.2 0.12 11.4 46.6 1.7 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Endostatin PF06482.11 CDJ52297.1 - 2 7.8 15.4 3.5 7.0 15.4 1.3 1 1 0 1 1 1 0 Collagenase NC10 and Endostatin Suf PF05843.14 CDJ52297.1 - 3.8 7.4 13.0 6.5 6.6 13.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1674 PF07896.12 CDJ52298.1 - 4e-07 30.4 12.7 3.2e-06 27.5 12.4 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Serinc PF03348.15 CDJ52298.1 - 0.0064 15.5 0.4 0.0078 15.2 0.4 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Suf PF05843.14 CDJ52298.1 - 0.013 15.5 10.7 0.017 15.2 10.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4179 PF13786.6 CDJ52298.1 - 0.016 15.6 0.1 0.027 15.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Velvet PF11754.8 CDJ52298.1 - 0.024 14.6 7.6 0.026 14.5 7.6 1.1 1 0 0 1 1 1 0 Velvet factor DDHD PF02862.17 CDJ52298.1 - 0.038 14.2 5.6 0.043 14.0 5.6 1.1 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 CDJ52298.1 - 0.093 12.8 6.3 0.12 12.5 6.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BAF1_ABF1 PF04684.13 CDJ52298.1 - 0.11 11.6 12.9 0.13 11.3 12.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor eIF-3_zeta PF05091.12 CDJ52298.1 - 0.13 11.2 14.6 0.15 11.0 14.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CobT PF06213.12 CDJ52298.1 - 0.13 11.6 16.3 0.19 11.1 16.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SelP_N PF04592.14 CDJ52298.1 - 0.17 11.3 16.0 0.22 10.9 16.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region V_ATPase_I PF01496.19 CDJ52298.1 - 0.17 9.7 9.6 0.21 9.5 9.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2232 PF09991.9 CDJ52298.1 - 0.24 10.5 1.8 0.33 10.1 1.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Endostatin PF06482.11 CDJ52298.1 - 0.31 10.5 10.1 0.39 10.1 10.1 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin BORG_CEP PF14957.6 CDJ52298.1 - 0.33 12.1 6.4 0.47 11.6 6.4 1.3 1 0 0 1 1 1 0 Cdc42 effector SID-1_RNA_chan PF13965.6 CDJ52298.1 - 0.37 9.1 1.0 0.44 8.9 1.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SpoIIP PF07454.11 CDJ52298.1 - 0.43 10.0 12.2 0.57 9.6 12.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDJ52298.1 - 0.56 10.0 12.7 0.7 9.7 12.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ52298.1 - 0.61 9.0 8.6 0.73 8.8 8.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 EPL1 PF10513.9 CDJ52298.1 - 0.65 10.4 10.4 1.2 9.5 10.4 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like API5 PF05918.11 CDJ52298.1 - 0.71 8.6 12.8 0.91 8.3 12.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Paramyxo_ncap PF00973.19 CDJ52298.1 - 0.76 8.6 4.4 0.85 8.5 4.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Presenilin PF01080.17 CDJ52298.1 - 0.8 8.4 16.2 0.99 8.1 16.2 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 CDJ52298.1 - 0.81 9.4 7.3 1 9.1 7.3 1.1 1 0 0 1 1 1 0 Connexin OATP PF03137.20 CDJ52298.1 - 0.82 7.9 4.5 1 7.6 4.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AF-4 PF05110.13 CDJ52298.1 - 0.94 7.5 16.2 1.1 7.2 16.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FHIPEP PF00771.20 CDJ52298.1 - 1.1 7.6 3.9 1.4 7.2 3.9 1.2 1 0 0 1 1 1 0 FHIPEP family DUF4228 PF14009.6 CDJ52298.1 - 1.1 9.6 9.0 1.5 9.2 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Hamartin PF04388.12 CDJ52298.1 - 1.1 7.8 11.5 1.5 7.4 11.5 1.1 1 0 0 1 1 1 0 Hamartin protein FPN1 PF06963.12 CDJ52298.1 - 1.2 7.6 3.3 1.6 7.2 3.3 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Hid1 PF12722.7 CDJ52298.1 - 1.7 6.7 10.2 1.9 6.5 10.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Coilin_N PF15862.5 CDJ52298.1 - 1.8 8.4 12.5 2.9 7.7 12.5 1.4 1 0 0 1 1 1 0 Coilin N-terminus FAM60A PF15396.6 CDJ52298.1 - 2.1 8.3 7.7 2.7 8.0 7.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A NPR3 PF03666.13 CDJ52298.1 - 2.6 6.7 9.8 3.3 6.4 9.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 THOC2_N PF16134.5 CDJ52298.1 - 2.6 6.5 8.0 3.2 6.3 8.0 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus EOS1 PF12326.8 CDJ52298.1 - 2.7 7.9 5.0 3.6 7.5 5.0 1.2 1 0 0 1 1 1 0 N-glycosylation protein EIIBC-GUT_N PF03612.14 CDJ52298.1 - 3.1 7.5 8.9 4.7 6.9 8.9 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AIF_C PF14721.6 CDJ52298.1 - 3.1 8.1 10.1 4.8 7.6 10.1 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CLN3 PF02487.17 CDJ52298.1 - 3.3 6.6 7.5 4.2 6.3 7.5 1.1 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 CDJ52298.1 - 3.7 6.3 6.9 4.3 6.1 6.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Sec62 PF03839.16 CDJ52298.1 - 3.8 7.0 6.7 5 6.6 6.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Activator_LAG-3 PF11498.8 CDJ52298.1 - 3.9 6.3 49.7 0.046 12.7 36.2 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Ndc1_Nup PF09531.10 CDJ52298.1 - 4.5 5.8 12.5 5.3 5.6 12.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MDM10 PF12519.8 CDJ52298.1 - 4.8 5.9 9.0 5.9 5.6 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 R_equi_Vir PF05526.11 CDJ52298.1 - 5.3 6.9 11.8 7.6 6.4 11.8 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein CPSF100_C PF13299.6 CDJ52298.1 - 5.4 7.2 10.0 8.6 6.5 10.0 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ctr PF04145.15 CDJ52298.1 - 5.8 7.5 5.7 8.8 6.9 5.7 1.3 1 0 0 1 1 1 0 Ctr copper transporter family DUF1980 PF09323.10 CDJ52298.1 - 5.9 6.8 8.0 8 6.3 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Paf1 PF03985.13 CDJ52298.1 - 6 5.8 14.6 7.5 5.4 14.6 1.1 1 0 0 1 1 1 0 Paf1 DUF3295 PF11702.8 CDJ52298.1 - 6.1 6.1 16.7 7.6 5.8 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF3408 PF11888.8 CDJ52298.1 - 6.6 6.9 13.8 10 6.3 13.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) FAM176 PF14851.6 CDJ52298.1 - 6.7 6.4 6.7 9.3 5.9 6.7 1.2 1 0 0 1 1 1 0 FAM176 family PAT1 PF09770.9 CDJ52298.1 - 7.3 4.7 27.2 9.5 4.3 27.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 CDJ52298.1 - 9.4 6.9 32.1 5.9 7.5 28.9 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF3_subunit PF08597.10 CDJ52298.1 - 9.6 6.0 18.2 13 5.6 18.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Bax1-I PF01027.20 CDJ52301.1 - 5e-20 72.2 15.1 3.5e-15 56.4 7.3 2.0 1 1 1 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 Cpn60_TCP1 PF00118.24 CDJ52302.1 - 8.4e-59 199.5 0.1 1e-58 199.2 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Neur_chan_memb PF02932.16 CDJ52304.1 - 0.012 15.7 15.7 0.012 15.7 15.7 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RskA PF10099.9 CDJ52305.1 - 0.00017 22.0 6.7 0.00037 20.9 6.7 1.5 1 1 0 1 1 1 1 Anti-sigma-K factor rskA ArsP_2 PF11449.8 CDJ52305.1 - 0.0013 18.0 1.9 0.0014 17.9 1.9 1.0 1 0 0 1 1 1 1 Putative, 10TM heavy-metal exporter Peptidase_S49_N PF08496.10 CDJ52305.1 - 0.0077 16.3 15.5 0.017 15.2 2.2 2.1 2 0 0 2 2 2 1 Peptidase family S49 N-terminal Conotoxin PF02950.17 CDJ52305.1 - 0.0079 17.2 3.5 0.0079 17.2 3.5 2.3 2 0 0 2 2 2 1 Conotoxin Presenilin PF01080.17 CDJ52305.1 - 0.008 15.0 12.2 0.0099 14.7 12.2 1.1 1 0 0 1 1 1 1 Presenilin Gti1_Pac2 PF09729.9 CDJ52305.1 - 0.013 15.6 7.7 0.02 15.0 7.7 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Spt20 PF12090.8 CDJ52305.1 - 0.013 15.1 41.6 0.11 12.1 19.0 2.0 2 0 0 2 2 2 0 Spt20 family DUF2681 PF10883.8 CDJ52305.1 - 0.026 14.9 11.8 0.026 14.9 11.8 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF2681) FAM60A PF15396.6 CDJ52305.1 - 0.035 14.1 9.0 0.044 13.8 9.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Connexin PF00029.19 CDJ52305.1 - 0.044 13.5 10.7 0.26 11.0 0.4 2.0 2 0 0 2 2 2 0 Connexin Eapp_C PF10238.9 CDJ52305.1 - 0.048 13.7 17.6 0.7 10.0 2.5 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein CAF1 PF04857.20 CDJ52305.1 - 0.055 12.6 8.5 0.069 12.3 8.5 1.0 1 0 0 1 1 1 0 CAF1 family ribonuclease EphA2_TM PF14575.6 CDJ52305.1 - 0.11 13.4 1.5 0.11 13.4 1.5 2.3 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Cytochrom_B_N_2 PF13631.6 CDJ52305.1 - 0.28 11.2 0.6 1.9 8.5 0.1 2.0 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB AUX_IAA PF02309.16 CDJ52305.1 - 0.29 11.0 8.1 0.37 10.6 8.1 1.1 1 0 0 1 1 1 0 AUX/IAA family GWT1 PF06423.12 CDJ52305.1 - 0.29 11.2 1.4 2.7 8.1 0.0 2.1 2 0 0 2 2 2 0 GWT1 Afi1 PF07792.12 CDJ52305.1 - 0.3 11.6 13.1 1.6 9.2 1.5 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking eIF-3_zeta PF05091.12 CDJ52305.1 - 0.3 10.0 22.7 0.37 9.7 4.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PRC2_HTH_1 PF18118.1 CDJ52305.1 - 0.36 11.7 13.4 1.1 10.1 1.5 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain GRP PF07172.11 CDJ52305.1 - 0.44 11.3 2.8 1.3 9.8 0.1 2.2 2 0 0 2 2 2 0 Glycine rich protein family AP3D1 PF06375.11 CDJ52305.1 - 0.45 10.7 15.6 0.15 12.3 4.1 2.0 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 MDM10 PF12519.8 CDJ52305.1 - 0.53 9.1 9.6 0.74 8.6 9.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Pinin_SDK_memA PF04696.13 CDJ52305.1 - 0.59 10.2 32.9 1.8 8.7 13.5 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region FKS1_dom1 PF14288.6 CDJ52305.1 - 0.6 10.5 8.1 1.1 9.6 2.2 2.1 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 RuvC_III PF18541.1 CDJ52305.1 - 0.72 9.8 15.2 2.3 8.1 2.0 2.0 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 EIIBC-GUT_N PF03612.14 CDJ52305.1 - 0.78 9.5 13.4 2.3 7.9 2.0 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF702 PF05142.12 CDJ52305.1 - 0.9 10.0 18.6 0.24 11.9 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Orf78 PF06024.12 CDJ52305.1 - 0.97 9.8 8.3 4.9 7.5 0.7 2.2 2 0 0 2 2 2 0 Orf78 (ac78) DUF1980 PF09323.10 CDJ52305.1 - 1.2 9.0 9.7 3.7 7.4 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) EPL1 PF10513.9 CDJ52305.1 - 1.3 9.4 18.4 0.43 11.0 3.0 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like XRN_M PF17846.1 CDJ52305.1 - 1.4 7.7 9.1 2 7.3 9.1 1.2 1 0 0 1 1 1 0 Xrn1 helical domain eIF_4EBP PF05456.11 CDJ52305.1 - 1.7 8.6 8.6 1.1 9.2 0.5 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Claudin_2 PF13903.6 CDJ52305.1 - 1.7 8.3 4.5 0.42 10.3 0.4 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TERB2 PF15101.6 CDJ52305.1 - 2.1 8.3 23.4 0.85 9.6 5.1 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 BRF1 PF07741.13 CDJ52305.1 - 2.4 8.6 25.5 2.2 8.7 11.6 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Sec62 PF03839.16 CDJ52305.1 - 2.8 7.4 12.9 2.7 7.4 1.1 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 Pet20 PF08692.10 CDJ52305.1 - 3.1 8.5 7.6 13 6.5 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 RPA43_OB PF17875.1 CDJ52305.1 - 3.5 8.2 14.1 3.9 8.1 1.9 2.1 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DNApol_Exo PF18136.1 CDJ52305.1 - 3.8 6.6 15.4 0.67 9.0 1.5 2.0 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain FHIPEP PF00771.20 CDJ52305.1 - 3.9 5.8 17.9 0.015 13.8 6.4 1.9 1 1 1 2 2 2 0 FHIPEP family Rsc14 PF08586.10 CDJ52305.1 - 4.7 8.1 11.8 4.1 8.3 1.3 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Ndc1_Nup PF09531.10 CDJ52305.1 - 4.8 5.7 14.6 5.9 5.5 14.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SpoIIP PF07454.11 CDJ52305.1 - 5.6 6.4 17.7 4.4 6.7 4.5 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SID-1_RNA_chan PF13965.6 CDJ52305.1 - 7.2 4.9 7.9 14 3.9 7.7 1.5 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 PSCyt3 PF07627.11 CDJ52305.1 - 7.2 7.0 10.9 0.69 10.2 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) PH_4 PF15404.6 CDJ52305.1 - 8.7 6.1 13.5 2.5 7.9 1.3 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain CNDH2_M PF16869.5 CDJ52305.1 - 8.9 7.0 14.3 5 7.8 3.1 2.1 2 0 0 2 2 2 0 PF16858 Alph_Pro_TM PF09608.10 CDJ52306.1 - 8.6 6.1 9.0 9.2 6.0 9.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) GTP_EFTU PF00009.27 CDJ52307.1 - 3.7e-15 56.0 0.0 3.7e-15 56.0 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDJ52307.1 - 0.006 16.7 0.3 4.7 7.4 0.1 2.6 2 0 0 2 2 2 2 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CDJ52307.1 - 0.042 13.9 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase SUIM_assoc PF16619.5 CDJ52307.1 - 0.056 13.5 0.2 0.056 13.5 0.2 6.5 3 2 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RsgA_GTPase PF03193.16 CDJ52307.1 - 0.19 11.6 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase SAPS PF04499.15 CDJ52307.1 - 0.36 9.5 9.4 2.6 6.7 0.4 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 CDJ52307.1 - 2.2 8.3 15.1 7.3 6.6 0.8 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ52309.1 - 0.0014 17.5 1.0 0.0017 17.2 1.0 1.2 1 0 0 1 1 1 1 Presenilin DUF4228 PF14009.6 CDJ52309.1 - 0.054 13.9 3.2 0.16 12.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Neur_chan_memb PF02932.16 CDJ52309.1 - 0.068 13.2 0.6 0.086 12.9 0.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 CDJ52309.1 - 0.088 11.7 17.8 0.13 11.2 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Myc_N PF01056.18 CDJ52309.1 - 0.11 12.4 8.7 0.18 11.7 8.2 1.6 1 1 0 1 1 1 0 Myc amino-terminal region RPA43_OB PF17875.1 CDJ52309.1 - 0.13 12.9 3.0 0.3 11.7 0.6 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I SpoIIP PF07454.11 CDJ52309.1 - 0.15 11.5 5.8 0.21 11.0 5.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Zip PF02535.22 CDJ52309.1 - 0.16 11.2 1.0 0.26 10.5 1.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4820 PF16091.5 CDJ52309.1 - 0.28 10.5 6.3 0.55 9.6 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Band_3_cyto PF07565.13 CDJ52309.1 - 0.5 10.1 2.9 0.73 9.6 2.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FHIPEP PF00771.20 CDJ52309.1 - 0.51 8.7 1.6 0.91 7.9 1.6 1.3 1 0 0 1 1 1 0 FHIPEP family FAM60A PF15396.6 CDJ52309.1 - 0.6 10.1 3.2 0.94 9.4 3.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF3464 PF11947.8 CDJ52309.1 - 1 9.1 5.5 2.4 7.9 5.5 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4746 PF15928.5 CDJ52309.1 - 2.3 7.6 7.5 4.5 6.6 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF913 PF06025.12 CDJ52309.1 - 2.3 7.1 4.2 3.4 6.5 4.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 CDJ52309.1 - 2.4 7.9 4.9 3.5 7.3 4.9 1.1 1 0 0 1 1 1 0 Connexin DUF1980 PF09323.10 CDJ52309.1 - 3.1 7.7 8.3 4.8 7.0 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PPL5 PF18168.1 CDJ52309.1 - 3.8 6.7 5.3 5.4 6.2 5.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 TERB2 PF15101.6 CDJ52309.1 - 6.3 6.8 13.5 9.9 6.2 13.5 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ndc1_Nup PF09531.10 CDJ52309.1 - 6.7 5.3 6.1 0.52 8.9 0.2 1.8 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Tim54 PF11711.8 CDJ52309.1 - 8.1 5.1 10.6 15 4.2 10.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 UPF0560 PF10577.9 CDJ52309.1 - 8.7 4.7 13.6 12 4.2 13.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2722 PF10846.8 CDJ52310.1 - 0.0065 15.5 0.5 0.0065 15.5 0.5 11.8 9 3 1 10 10 10 2 Protein of unknown function (DUF2722) LCD1 PF09798.9 CDJ52310.1 - 5.5 5.4 0.0 5.5 5.4 0.0 6.3 6 2 0 6 6 6 0 DNA damage checkpoint protein Fe-S_biosyn PF01521.20 CDJ52311.1 - 1.2e-07 31.8 0.1 4.3e-05 23.7 0.0 2.6 2 1 0 2 2 2 2 Iron-sulphur cluster biosynthesis NDK PF00334.19 CDJ52312.1 - 5.7e-14 52.3 0.0 1.5e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 Nucleoside diphosphate kinase FAS_I_H PF18314.1 CDJ52312.1 - 0.093 12.3 0.2 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Fatty acid synthase type I helical domain CoA_binding_2 PF13380.6 CDJ52312.1 - 8.8 6.9 9.2 0.42 11.1 1.4 2.4 2 1 0 2 2 2 0 CoA binding domain AAA_5 PF07728.14 CDJ52313.1 - 6.2e-105 347.0 0.0 5e-21 75.1 0.0 10.9 10 0 0 10 10 10 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CDJ52313.1 - 1.5e-27 95.9 6.8 1.4e-11 44.5 0.5 4.7 4 0 0 4 4 3 3 Midasin AAA lid domain AAA PF00004.29 CDJ52313.1 - 1.8e-22 80.2 0.0 0.0094 16.4 0.0 7.3 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 CDJ52313.1 - 9.5e-19 67.4 0.0 2.6e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 CDJ52313.1 - 3.5e-18 65.7 0.0 0.00029 20.7 0.0 6.7 7 0 0 7 7 6 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ52313.1 - 3.8e-17 62.9 1.0 0.083 13.2 0.0 8.4 6 1 0 6 6 6 3 AAA domain Dynein_heavy PF03028.15 CDJ52313.1 - 2.5e-14 53.4 0.0 0.00012 22.2 0.0 6.4 6 0 0 6 6 5 2 Dynein heavy chain region D6 P-loop domain TsaE PF02367.17 CDJ52313.1 - 2.7e-14 53.3 2.9 0.3 11.1 0.1 6.5 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CDJ52313.1 - 5.1e-14 52.2 0.0 0.1 12.1 0.0 6.3 6 0 0 6 6 6 2 P-loop containing dynein motor region ABC_tran PF00005.27 CDJ52313.1 - 1.2e-12 48.5 0.1 0.5 10.9 0.0 8.0 7 0 0 7 7 6 3 ABC transporter Zeta_toxin PF06414.12 CDJ52313.1 - 4.6e-10 39.1 0.2 1.9 7.7 0.0 6.6 6 0 0 6 6 6 2 Zeta toxin AAA_33 PF13671.6 CDJ52313.1 - 8.2e-10 39.0 16.9 0.0066 16.6 0.0 8.6 8 0 0 8 8 7 3 AAA domain AAA_18 PF13238.6 CDJ52313.1 - 1.2e-09 38.8 0.0 0.28 11.7 0.0 7.6 7 0 0 7 7 7 1 AAA domain NACHT PF05729.12 CDJ52313.1 - 1.9e-08 34.4 10.2 0.14 12.0 0.0 7.0 6 0 0 6 6 6 2 NACHT domain DUF815 PF05673.13 CDJ52313.1 - 3.5e-08 32.9 2.9 0.011 14.9 0.1 5.8 6 0 0 6 6 6 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CDJ52313.1 - 5.3e-08 32.5 4.2 0.068 12.5 0.0 7.2 8 0 0 8 8 8 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 CDJ52313.1 - 1.8e-07 31.3 2.4 0.91 9.6 0.1 6.1 5 0 0 5 5 5 1 Sigma-54 interaction domain AAA_29 PF13555.6 CDJ52313.1 - 2.4e-07 30.4 0.2 4.1 7.2 0.0 6.8 6 0 0 6 6 6 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 CDJ52313.1 - 4.4e-07 29.8 1.4 5.5 6.7 0.0 6.5 7 0 0 7 7 6 0 Sigma-54 interaction domain AAA_16 PF13191.6 CDJ52313.1 - 4.9e-07 30.3 9.4 0.00028 21.3 0.6 17.3 18 1 2 20 20 8 5 AAA ATPase domain RNA_helicase PF00910.22 CDJ52313.1 - 6.4e-07 29.7 0.1 18 5.8 0.0 6.3 6 0 0 6 6 6 0 RNA helicase AAA_8 PF12780.7 CDJ52313.1 - 1.3e-05 24.7 0.0 0.084 12.2 0.0 4.4 5 0 0 5 5 4 1 P-loop containing dynein motor region D4 AAA_25 PF13481.6 CDJ52313.1 - 1.7e-05 24.5 11.6 1.2 8.7 0.1 8.6 8 0 0 8 8 8 1 AAA domain AAA_6 PF12774.7 CDJ52313.1 - 2.2e-05 23.6 0.0 0.9 8.4 0.0 5.3 5 0 0 5 5 5 1 Hydrolytic ATP binding site of dynein motor region VWA_2 PF13519.6 CDJ52313.1 - 2.7e-05 24.8 0.4 0.00059 20.5 0.0 3.9 2 0 0 2 2 1 1 von Willebrand factor type A domain RuvB_N PF05496.12 CDJ52313.1 - 6.5e-05 22.7 0.2 17 5.2 0.0 5.9 6 0 0 6 6 6 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 CDJ52313.1 - 0.00013 22.0 0.0 2.9 7.9 0.0 4.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Rad17 PF03215.15 CDJ52313.1 - 0.00021 21.3 1.6 3.2 7.6 0.0 5.4 6 0 0 6 6 6 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 CDJ52313.1 - 0.00039 20.4 0.7 7.3 6.5 0.0 5.1 5 0 0 5 5 5 0 RsgA GTPase T2SSE PF00437.20 CDJ52313.1 - 0.0012 18.0 0.1 1.8 7.6 0.0 4.4 5 0 0 5 5 5 1 Type II/IV secretion system protein TniB PF05621.11 CDJ52313.1 - 0.0018 17.8 0.0 1.3 8.4 0.0 4.4 4 0 0 4 4 4 1 Bacterial TniB protein VWA PF00092.28 CDJ52313.1 - 0.006 16.8 0.0 0.052 13.8 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain DEAD PF00270.29 CDJ52313.1 - 0.026 14.3 0.9 3.1 7.5 0.0 3.9 4 0 0 4 4 3 0 DEAD/DEAH box helicase Roc PF08477.13 CDJ52313.1 - 0.032 14.5 1.3 26 5.1 0.1 4.4 5 0 0 5 5 4 0 Ras of Complex, Roc, domain of DAPkinase dNK PF01712.19 CDJ52313.1 - 0.036 13.9 0.4 3.9 7.3 0.0 4.2 6 0 0 6 6 6 0 Deoxynucleoside kinase AAA_23 PF13476.6 CDJ52313.1 - 0.52 10.8 0.0 0.52 10.8 0.0 14.1 16 1 0 16 16 7 0 AAA domain DUF2722 PF10846.8 CDJ52315.1 - 0.00023 20.3 1.6 0.00023 20.3 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RXT2_N PF08595.11 CDJ52315.1 - 0.0061 16.6 0.3 0.0086 16.1 0.3 1.2 1 0 0 1 1 1 1 RXT2-like, N-terminal HATPase_c PF02518.26 CDJ52315.1 - 0.013 16.0 0.3 0.045 14.3 0.3 2.1 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UPF0560 PF10577.9 CDJ52315.1 - 0.21 10.1 5.0 0.25 9.8 5.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIA PF03153.13 CDJ52315.1 - 0.21 11.6 11.2 0.23 11.4 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ52315.1 - 0.23 11.0 16.6 0.32 10.6 16.6 1.1 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ52315.1 - 0.29 9.8 2.4 0.32 9.7 2.4 1.1 1 0 0 1 1 1 0 Presenilin Androgen_recep PF02166.16 CDJ52315.1 - 0.41 9.4 14.2 0.52 9.1 14.2 1.1 1 0 0 1 1 1 0 Androgen receptor DUF3464 PF11947.8 CDJ52315.1 - 0.53 10.0 2.7 0.78 9.5 2.7 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 eIF-3_zeta PF05091.12 CDJ52315.1 - 0.91 8.4 5.9 1 8.3 5.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.6 CDJ52315.1 - 2.2 6.1 13.6 2.6 5.8 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4834 PF16118.5 CDJ52315.1 - 4.4 8.3 8.4 8.2 7.5 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF5345 PF17280.2 CDJ52315.1 - 8.2 6.5 6.3 15 5.7 6.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) G0-G1_switch_2 PF15103.6 CDJ52316.1 - 0.076 13.4 2.2 8.3 6.9 0.0 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 Spt20 PF12090.8 CDJ52316.1 - 0.93 9.1 18.3 1 8.9 18.3 1.2 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ52317.1 - 0.00015 21.5 2.0 0.00025 20.8 2.0 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Velvet PF11754.8 CDJ52317.1 - 0.004 17.1 4.4 0.0048 16.9 4.4 1.3 1 0 0 1 1 1 1 Velvet factor CCSAP PF15748.5 CDJ52317.1 - 0.043 14.0 10.8 0.066 13.4 10.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF2126 PF09899.9 CDJ52317.1 - 0.065 11.3 3.7 0.082 11.0 3.7 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) TCP PF03634.13 CDJ52317.1 - 0.08 13.5 7.7 0.12 12.9 7.7 1.2 1 0 0 1 1 1 0 TCP family transcription factor SseC PF04888.12 CDJ52317.1 - 0.081 12.5 21.2 0.17 11.4 21.2 1.5 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Ndc1_Nup PF09531.10 CDJ52317.1 - 0.088 11.5 6.6 0.1 11.3 6.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 CDJ52317.1 - 0.16 11.6 26.5 0.25 10.9 26.5 1.4 1 0 0 1 1 1 0 Spt20 family DUF3464 PF11947.8 CDJ52317.1 - 0.17 11.6 2.3 0.31 10.8 2.3 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2151 PF10221.9 CDJ52317.1 - 0.24 9.9 2.6 0.3 9.6 2.6 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator GvpL_GvpF PF06386.11 CDJ52317.1 - 0.29 11.0 7.6 0.49 10.3 7.6 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PAT1 PF09770.9 CDJ52317.1 - 0.3 9.3 14.3 0.35 9.1 14.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1387 PF07139.11 CDJ52317.1 - 0.63 9.7 8.5 0.83 9.3 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) V_ATPase_I PF01496.19 CDJ52317.1 - 0.68 7.8 4.5 0.86 7.4 4.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ52317.1 - 1.2 7.8 12.1 0.016 14.0 4.1 1.7 2 0 0 2 2 2 0 Presenilin Herpes_pp85 PF04637.12 CDJ52317.1 - 1.3 7.4 3.4 2.1 6.6 3.4 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) GREB1 PF15782.5 CDJ52317.1 - 1.3 6.1 9.5 1.5 5.8 9.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 CDJ52317.1 - 1.4 8.9 3.7 1.9 8.5 3.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Activator_LAG-3 PF11498.8 CDJ52317.1 - 2.4 7.1 33.6 4.1 6.3 33.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 eIF-3_zeta PF05091.12 CDJ52317.1 - 4.1 6.3 10.7 5.3 5.9 10.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIIBC-GUT_N PF03612.14 CDJ52317.1 - 4.6 6.9 6.2 8.8 6.0 6.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FAM176 PF14851.6 CDJ52317.1 - 5 6.8 6.3 15 5.2 1.3 2.4 2 0 0 2 2 2 0 FAM176 family Suf PF05843.14 CDJ52317.1 - 6.5 6.7 13.0 9.3 6.1 13.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2079 PF09852.9 CDJ52317.1 - 8.8 5.1 7.9 17 4.1 7.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Peptidase_S49_N PF08496.10 CDJ52319.1 - 0.63 10.1 13.9 0.13 12.3 1.3 3.1 3 0 0 3 3 3 0 Peptidase family S49 N-terminal TFIIA PF03153.13 CDJ52320.1 - 0.00056 20.0 19.2 0.0011 19.1 19.2 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ52320.1 - 0.052 11.8 13.3 0.07 11.4 13.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NPR3 PF03666.13 CDJ52320.1 - 0.065 12.0 2.9 0.088 11.6 2.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SARAF PF06682.12 CDJ52320.1 - 0.12 12.0 8.8 0.68 9.5 3.2 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CitMHS_2 PF16980.5 CDJ52320.1 - 0.14 10.8 1.4 0.22 10.1 1.4 1.2 1 0 0 1 1 1 0 Putative citrate transport FAM60A PF15396.6 CDJ52320.1 - 0.22 11.5 2.5 0.36 10.8 2.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CPSF100_C PF13299.6 CDJ52320.1 - 0.3 11.2 7.6 0.6 10.3 6.8 1.9 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal Neur_chan_memb PF02932.16 CDJ52320.1 - 0.86 9.6 3.5 1.3 9.0 3.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ52320.1 - 1.1 9.0 6.7 1.8 8.3 6.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pox_P21 PF05313.12 CDJ52320.1 - 1.5 8.3 4.4 2.9 7.4 4.4 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Presenilin PF01080.17 CDJ52320.1 - 2 7.1 11.7 4.1 6.1 11.7 1.4 1 0 0 1 1 1 0 Presenilin Keratin_2_head PF16208.5 CDJ52320.1 - 3.2 7.9 12.9 7.4 6.7 12.9 1.6 1 0 0 1 1 1 0 Keratin type II head CLN3 PF02487.17 CDJ52320.1 - 3.4 6.6 5.8 6.3 5.7 5.8 1.3 1 0 0 1 1 1 0 CLN3 protein RR_TM4-6 PF06459.12 CDJ52320.1 - 3.4 7.4 8.5 5.7 6.7 8.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MMR1 PF08505.10 CDJ52320.1 - 5.1 7.3 11.5 8.7 6.5 11.5 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Bud13 PF09736.9 CDJ52320.1 - 5.8 7.3 12.9 11 6.4 12.9 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Conotoxin PF02950.17 CDJ52320.1 - 6.2 7.9 9.4 2.4 9.2 2.8 3.1 2 0 0 2 2 2 0 Conotoxin DUF4050 PF13259.6 CDJ52320.1 - 6.8 7.0 8.9 14 6.0 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF4647 PF15504.6 CDJ52320.1 - 8.8 5.3 15.1 13 4.7 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) AUX_IAA PF02309.16 CDJ52320.1 - 8.8 6.1 6.8 16 5.3 6.8 1.3 1 0 0 1 1 1 0 AUX/IAA family Rtf2 PF04641.12 CDJ52320.1 - 9.9 5.4 12.3 22 4.3 12.3 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger SDA1 PF05285.12 CDJ52321.1 - 0.047 13.1 11.5 0.062 12.7 11.5 1.3 1 0 0 1 1 1 0 SDA1 Apt1 PF10351.9 CDJ52321.1 - 0.047 12.6 22.2 0.055 12.3 22.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Utp14 PF04615.13 CDJ52321.1 - 2.2 6.8 18.5 2.8 6.4 18.5 1.3 1 0 0 1 1 1 0 Utp14 protein PNISR PF15996.5 CDJ52321.1 - 3.3 7.9 20.2 8 6.7 20.2 1.6 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SPX PF03105.19 CDJ52321.1 - 3.6 7.4 28.6 5.3 6.8 28.6 1.2 1 0 0 1 1 1 0 SPX domain Nop14 PF04147.12 CDJ52321.1 - 6 4.9 10.1 8.3 4.5 10.1 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 CDJ52321.1 - 7 5.1 21.9 9 4.7 21.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SR-25 PF10500.9 CDJ52322.1 - 0.00043 20.0 8.3 0.00043 20.0 8.3 6.0 5 2 1 7 7 7 1 Nuclear RNA-splicing-associated protein SRP-alpha_N PF04086.13 CDJ52322.1 - 0.0027 17.7 4.5 0.0027 17.7 4.5 4.8 2 2 2 4 4 4 1 Signal recognition particle, alpha subunit, N-terminal DUF2722 PF10846.8 CDJ52322.1 - 0.0064 15.5 1.7 0.0064 15.5 1.7 4.8 3 1 0 3 3 3 2 Protein of unknown function (DUF2722) SID-1_RNA_chan PF13965.6 CDJ52322.1 - 0.72 8.2 7.5 0.21 10.0 3.9 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TFIIA PF03153.13 CDJ52324.1 - 0.58 10.1 7.7 0.6 10.0 7.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3043 PF11241.8 CDJ52325.1 - 2.2 8.3 4.4 0.51 10.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Pet20 PF08692.10 CDJ52327.1 - 0.032 14.9 1.6 0.034 14.9 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Spt20 PF12090.8 CDJ52327.1 - 0.033 13.8 25.1 0.043 13.4 25.1 1.2 1 0 0 1 1 1 0 Spt20 family Folliculin PF11704.8 CDJ52327.1 - 0.97 9.3 5.8 1.1 9.1 5.8 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4407 PF14362.6 CDJ52327.1 - 2.3 7.5 12.6 2.6 7.3 12.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZYG-11_interact PF05884.12 CDJ52327.1 - 8.2 5.7 7.7 9.1 5.6 7.7 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 YscW PF09619.10 CDJ52328.1 - 6.7e-08 32.8 0.1 3.8e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Type III secretion system lipoprotein chaperone (YscW) SUIM_assoc PF16619.5 CDJ52328.1 - 0.024 14.7 2.3 0.064 13.3 2.3 1.8 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Hemagglutinin PF00509.18 CDJ52329.1 - 0.02 13.3 0.7 0.045 12.1 0.7 1.6 1 0 0 1 1 1 0 Haemagglutinin Filament_head PF04732.14 CDJ52329.1 - 0.92 10.4 35.2 0.67 10.9 12.5 2.4 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region RAP1 PF07218.11 CDJ52329.1 - 1.3 7.2 30.8 0.017 13.4 5.4 2.1 1 1 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) DUF2371 PF10177.9 CDJ52330.1 - 0.2 11.8 1.0 0.69 10.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF755 PF05501.11 CDJ52330.1 - 2.3 8.5 28.7 0.034 14.4 13.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF755) REV PF00424.18 CDJ52331.1 - 0.013 15.5 0.4 0.013 15.5 0.4 4.4 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) SR-25 PF10500.9 CDJ52332.1 - 0.0025 17.5 11.6 0.0025 17.5 11.6 9.6 5 2 4 9 9 9 3 Nuclear RNA-splicing-associated protein FAM60A PF15396.6 CDJ52333.1 - 6.4 6.7 15.3 6.8 6.6 15.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Zip PF02535.22 CDJ52333.1 - 8.5 5.5 9.8 9.9 5.3 9.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Lin-8 PF03353.15 CDJ52333.1 - 9.1 5.7 26.9 11 5.5 26.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2722 PF10846.8 CDJ52334.1 - 9.2e-05 21.6 10.6 9.3e-05 21.6 10.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) V_ATPase_I PF01496.19 CDJ52334.1 - 0.0042 15.1 1.9 0.0047 14.9 1.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Suf PF05843.14 CDJ52334.1 - 0.0066 16.5 4.4 0.0066 16.5 4.4 1.0 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Connexin PF00029.19 CDJ52334.1 - 0.0093 15.8 2.0 0.011 15.5 2.0 1.1 1 0 0 1 1 1 1 Connexin OATP PF03137.20 CDJ52334.1 - 0.013 13.8 0.8 0.016 13.5 0.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family NUDIX_2 PF13869.6 CDJ52334.1 - 0.023 14.3 0.3 0.026 14.1 0.3 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase AIF_C PF14721.6 CDJ52334.1 - 0.027 14.8 0.7 0.03 14.7 0.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Med15 PF09606.10 CDJ52334.1 - 0.041 12.6 14.1 0.044 12.5 14.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ52334.1 - 0.047 13.7 14.9 0.052 13.5 14.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ52334.1 - 0.092 12.3 24.9 0.12 12.0 24.9 1.1 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 CDJ52334.1 - 0.15 12.7 9.6 0.17 12.5 9.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CDJ52334.1 - 0.24 10.1 4.3 0.24 10.1 4.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CDJ52334.1 - 0.39 10.0 3.9 0.41 10.0 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Band_3_cyto PF07565.13 CDJ52334.1 - 0.45 10.3 4.0 0.53 10.1 4.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3464 PF11947.8 CDJ52334.1 - 0.46 10.2 5.1 0.55 10.0 5.1 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4175 PF13779.6 CDJ52334.1 - 0.46 8.3 15.5 0.52 8.1 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EIIBC-GUT_N PF03612.14 CDJ52334.1 - 0.52 10.0 3.8 0.58 9.9 3.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4834 PF16118.5 CDJ52334.1 - 0.67 11.0 9.7 1.1 10.3 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Protamine_P2 PF00841.19 CDJ52334.1 - 1.9 9.0 10.6 2.7 8.6 10.6 1.2 1 0 0 1 1 1 0 Sperm histone P2 Androgen_recep PF02166.16 CDJ52334.1 - 1.9 7.2 18.4 2 7.1 18.4 1.0 1 0 0 1 1 1 0 Androgen receptor eIF-3_zeta PF05091.12 CDJ52334.1 - 2.1 7.2 9.4 2.2 7.1 9.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UPF0560 PF10577.9 CDJ52334.1 - 3 6.2 12.1 3.3 6.1 12.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Coilin_N PF15862.5 CDJ52334.1 - 4.7 7.0 10.7 7.3 6.4 10.7 1.3 1 0 0 1 1 1 0 Coilin N-terminus eIF-3_zeta PF05091.12 CDJ52335.1 - 0.047 12.7 14.4 0.053 12.5 14.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RBP_receptor PF14752.6 CDJ52335.1 - 0.11 11.0 10.3 0.18 10.3 10.3 1.3 1 0 0 1 1 1 0 Retinol binding protein receptor DUF2828 PF11443.8 CDJ52335.1 - 2.2 6.3 16.3 3 5.8 16.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Connexin PF00029.19 CDJ52335.1 - 5 6.8 14.8 6.9 6.4 14.8 1.2 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 CDJ52335.1 - 6.1 5.8 15.4 4.6 6.2 14.3 1.3 1 1 0 1 1 1 0 CLN3 protein ATP-synt_ab_C PF00306.27 CDJ52336.1 - 1.5e-15 57.7 6.3 2.5e-09 37.5 0.5 2.0 1 1 1 2 2 2 2 ATP synthase alpha/beta chain, C terminal domain Caldesmon PF02029.15 CDJ52337.1 - 0.022 13.5 32.6 0.024 13.4 32.6 1.1 1 0 0 1 1 1 0 Caldesmon AF-4 PF05110.13 CDJ52337.1 - 0.096 10.8 46.4 0.1 10.6 46.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PAT1 PF09770.9 CDJ52337.1 - 0.26 9.5 59.4 0.28 9.4 59.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ52337.1 - 2.7 5.0 33.6 3 4.9 33.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp-B-Hydro_N PF05279.11 CDJ52337.1 - 3.4 7.7 28.1 4.3 7.3 28.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FAM60A PF15396.6 CDJ52338.1 - 0.64 10.0 21.9 0.77 9.7 21.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 CDJ52338.1 - 0.76 8.5 32.2 0.91 8.2 32.2 1.1 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 CDJ52338.1 - 0.81 9.4 25.6 0.93 9.2 25.6 1.1 1 0 0 1 1 1 0 AAA domain CCSAP PF15748.5 CDJ52338.1 - 1.3 9.1 31.5 1.6 8.9 31.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Lin-8 PF03353.15 CDJ52338.1 - 1.3 8.5 30.6 1.7 8.1 30.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 CDJ52338.1 - 2 7.4 30.7 2.1 7.3 30.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ52338.1 - 2.2 8.1 30.9 2.7 7.7 30.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 CDJ52338.1 - 3.5 5.4 27.1 4.2 5.2 27.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PA26 PF04636.13 CDJ52338.1 - 3.6 6.4 21.1 4.2 6.2 21.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PAT1 PF09770.9 CDJ52338.1 - 4 5.6 48.4 4.6 5.4 48.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ52338.1 - 4.6 5.4 22.1 5.5 5.2 22.1 1.0 1 0 0 1 1 1 0 CDC45-like protein MDM10 PF12519.8 CDJ52338.1 - 5.8 5.7 25.6 7.2 5.4 25.6 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Suf PF05843.14 CDJ52338.1 - 7.6 6.4 35.6 12 5.8 35.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SMC_N PF02463.19 CDJ52338.1 - 8.7 5.7 16.3 11 5.4 16.3 1.0 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain SAGA-Tad1 PF12767.7 CDJ52338.1 - 9.6 5.9 28.5 11 5.7 28.5 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit HEAT PF02985.22 CDJ52339.1 - 0.00053 20.0 12.1 0.2 12.0 0.2 6.3 5 0 0 5 5 5 2 HEAT repeat DUF4667 PF15700.5 CDJ52339.1 - 0.00089 19.4 1.5 0.00089 19.4 1.5 5.1 4 1 0 4 4 4 2 Domain of unknown function (DUF4667) Cnd1 PF12717.7 CDJ52339.1 - 0.016 15.3 0.0 0.11 12.6 0.0 2.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 GHMP_kinases_N PF00288.26 CDJ52340.1 - 1.8 8.9 0.0 1.8 8.9 0.0 4.7 4 0 0 4 4 4 0 GHMP kinases N terminal domain Caldesmon PF02029.15 CDJ52340.1 - 2.5 6.8 61.3 0.068 11.9 8.7 2.2 2 0 0 2 2 2 0 Caldesmon Pox_Ag35 PF03286.14 CDJ52340.1 - 2.8 7.7 39.0 2.3 8.0 9.3 2.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC45 PF02724.14 CDJ52340.1 - 4 5.6 56.2 2.7 6.2 33.9 2.3 2 0 0 2 2 2 0 CDC45-like protein LMBR1 PF04791.16 CDJ52340.1 - 8.4 5.2 23.5 0.17 10.8 10.8 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein RRP7 PF12923.7 CDJ52341.1 - 3.4e-07 30.4 0.4 6.4e-07 29.5 0.4 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF5093 PF17011.5 CDJ52341.1 - 0.0032 17.7 0.1 0.005 17.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5093) RRM_Rrp7 PF17799.1 CDJ52341.1 - 0.0043 16.9 0.0 0.0057 16.5 0.0 1.3 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RskA PF10099.9 CDJ52341.1 - 8.4 6.7 21.1 0.19 12.0 14.6 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ52342.1 - 0.002 18.5 6.9 0.002 18.5 6.9 11.6 3 3 5 8 8 8 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ52342.1 - 0.0021 17.7 14.9 0.0021 17.7 14.9 9.4 8 1 1 9 9 9 6 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ52342.1 - 0.013 15.7 11.9 0.013 15.7 11.9 12.7 7 3 4 11 11 11 0 Early growth response N-terminal domain SR-25 PF10500.9 CDJ52344.1 - 8e-06 25.6 0.8 1.1e-05 25.1 0.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ52344.1 - 0.047 13.8 2.6 0.047 13.8 2.6 1.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Vps16_N PF04841.13 CDJ52344.1 - 0.066 12.0 0.2 4.6 5.9 0.0 2.2 1 1 1 2 2 2 0 Vps16, N-terminal region CoA_transf_3 PF02515.17 CDJ52346.1 - 5.4 6.0 12.0 6.2 5.8 12.0 1.1 1 0 0 1 1 1 0 CoA-transferase family III TYW3 PF02676.14 CDJ52346.1 - 5.6 6.3 10.3 5.2 6.4 9.5 1.3 1 1 0 1 1 1 0 Methyltransferase TYW3 NAD_binding_4 PF07993.12 CDJ52347.1 - 7.4e-31 107.2 7.7 4e-18 65.5 0.1 4.3 3 1 1 4 4 4 3 Male sterility protein Sterile PF03015.19 CDJ52347.1 - 5.6e-14 52.1 0.0 1.3e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 CDJ52347.1 - 3.7e-10 39.6 0.0 7.3e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase SID-1_RNA_chan PF13965.6 CDJ52347.1 - 0.19 10.1 13.2 2 6.7 0.2 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Semialdhyde_dh PF01118.24 CDJ52347.1 - 0.37 11.2 0.1 0.37 11.2 0.1 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain SPX PF03105.19 CDJ52347.1 - 2.4 8.0 34.9 0.21 11.5 1.9 2.8 3 0 0 3 3 3 0 SPX domain FAM60A PF15396.6 CDJ52347.1 - 3.1 7.7 36.9 1.6 8.7 21.7 2.6 2 0 0 2 2 2 0 Protein Family FAM60A eIF2A PF08662.11 CDJ52348.1 - 2e-09 37.6 0.0 3.4e-05 23.8 0.1 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CDJ52348.1 - 0.0017 18.6 0.0 0.011 16.0 0.0 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain SR-25 PF10500.9 CDJ52348.1 - 0.091 12.4 19.2 0.15 11.7 19.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ52348.1 - 0.76 8.6 2.5 1.1 8.1 2.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1180 PF06679.12 CDJ52348.1 - 2.9 8.3 5.6 4.4 7.7 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Nudc_N PF14050.6 CDJ52349.1 - 8.8e-19 67.3 0.0 1.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. SR-25 PF10500.9 CDJ52349.1 - 7.6e-05 22.4 18.1 7.6e-05 22.4 18.1 1.8 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein MctB PF11382.8 CDJ52349.1 - 0.071 12.8 17.3 0.1 12.3 4.7 2.3 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB PAP1 PF08601.10 CDJ52349.1 - 0.11 12.3 16.9 0.15 11.7 16.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 CDC27 PF09507.10 CDJ52349.1 - 0.35 10.2 19.9 0.6 9.4 19.9 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CCDC106 PF15794.5 CDJ52349.1 - 0.73 9.5 13.5 2.1 8.0 13.5 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 FAM60A PF15396.6 CDJ52349.1 - 1.9 8.5 9.3 0.5 10.3 5.8 1.8 2 0 0 2 2 2 0 Protein Family FAM60A Hid1 PF12722.7 CDJ52349.1 - 2.4 6.2 10.9 3.2 5.8 10.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CDJ52349.1 - 4 6.1 13.1 7.3 5.2 13.1 1.4 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CDJ52349.1 - 5.4 4.0 10.8 6.5 3.7 10.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MAJIN PF15077.6 CDJ52349.1 - 5.9 6.6 13.4 16 5.2 13.2 1.9 1 1 0 1 1 1 0 Membrane-anchored junction protein SPT16 PF08644.11 CDJ52349.1 - 6.2 7.0 7.7 8.4 6.6 0.1 2.8 3 0 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) SOG2 PF10428.9 CDJ52349.1 - 6.7 5.8 16.8 18 4.4 0.1 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Kelch_4 PF13418.6 CDJ52350.1 - 6.2e-10 38.9 0.5 1.2e-06 28.4 0.1 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ52350.1 - 7.7e-06 26.1 1.5 0.00092 19.4 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ52350.1 - 1.1e-05 25.5 0.2 0.06 13.7 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 CDJ52350.1 - 1.8e-05 24.6 0.2 0.015 15.3 0.1 2.9 2 1 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CDJ52350.1 - 0.0064 16.1 1.3 1.6 8.4 0.1 2.6 2 0 0 2 2 2 2 Kelch motif Tropomyosin_1 PF12718.7 CDJ52350.1 - 0.016 15.4 8.8 0.028 14.6 8.8 1.4 1 0 0 1 1 1 0 Tropomyosin like GAS PF13851.6 CDJ52350.1 - 0.023 14.1 10.8 0.035 13.5 10.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 CDJ52350.1 - 0.5 10.9 11.1 1.4 9.4 10.8 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region TMCO5 PF14992.6 CDJ52350.1 - 0.85 9.1 7.7 1.2 8.7 7.7 1.2 1 0 0 1 1 1 0 TMCO5 family Prominin PF05478.11 CDJ52350.1 - 0.94 7.4 5.4 1.3 6.9 5.4 1.1 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 CDJ52350.1 - 1.5 7.6 12.1 2.6 6.8 12.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein BORCS8 PF10167.9 CDJ52350.1 - 2.8 7.9 9.1 0.69 9.9 1.9 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 NPV_P10 PF05531.12 CDJ52350.1 - 5.7 7.5 7.5 0.58 10.6 1.5 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 CDJ52350.1 - 5.9 7.1 8.1 24 5.1 8.1 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4692 PF15763.5 CDJ52350.1 - 6 7.3 8.9 17 5.8 8.9 1.8 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) cNMP_binding PF00027.29 CDJ52353.1 - 2.1e-15 56.6 2.3 7.3e-10 38.8 0.3 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RskA PF10099.9 CDJ52353.1 - 2.6e-06 27.9 14.6 0.086 13.1 0.0 3.4 1 1 2 3 3 3 2 Anti-sigma-K factor rskA DUF3464 PF11947.8 CDJ52353.1 - 0.0021 17.8 0.0 0.0021 17.8 0.0 3.3 2 1 1 3 3 2 1 Photosynthesis affected mutant 68 DUF2207 PF09972.9 CDJ52353.1 - 0.0028 16.5 0.4 0.0028 16.5 0.4 2.7 2 1 0 2 2 1 1 Predicted membrane protein (DUF2207) HCO3_cotransp PF00955.21 CDJ52353.1 - 0.0035 16.3 10.7 0.075 11.9 0.4 2.1 2 0 0 2 2 2 2 HCO3- transporter family DUF913 PF06025.12 CDJ52353.1 - 0.0073 15.3 19.9 0.028 13.4 0.7 2.2 2 0 0 2 2 2 2 Domain of Unknown Function (DUF913) Connexin PF00029.19 CDJ52353.1 - 0.0088 15.8 0.7 0.0088 15.8 0.7 3.1 2 1 0 2 2 1 1 Connexin DUF755 PF05501.11 CDJ52353.1 - 0.029 14.6 21.1 0.029 14.6 21.1 3.2 2 1 1 3 3 1 0 Domain of unknown function (DUF755) BAF1_ABF1 PF04684.13 CDJ52353.1 - 0.087 11.9 32.1 0.12 11.4 32.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4778 PF16008.5 CDJ52353.1 - 2 8.4 35.8 0.24 11.4 13.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) DUF4407 PF14362.6 CDJ52353.1 - 7.7 5.8 59.6 35 3.6 59.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RskA PF10099.9 CDJ52354.1 - 0.0012 19.2 1.3 0.0012 19.2 1.3 4.9 2 2 1 3 3 3 2 Anti-sigma-K factor rskA RskA PF10099.9 CDJ52356.1 - 0.0011 19.3 0.2 0.0011 19.3 0.2 4.4 1 1 2 3 3 3 1 Anti-sigma-K factor rskA Hamartin PF04388.12 CDJ52356.1 - 4.3 5.9 41.2 5.4 5.6 41.2 1.0 1 0 0 1 1 1 0 Hamartin protein DUF812 PF05667.11 CDJ52356.1 - 6.5 5.5 47.6 8.6 5.1 47.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Glyco_hydro_9 PF00759.19 CDJ52357.1 - 0.028 13.8 8.2 0.03 13.8 8.2 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Herpes_U55 PF06501.11 CDJ52357.1 - 0.034 12.9 0.2 0.037 12.8 0.2 1.0 1 0 0 1 1 1 0 Human herpesvirus U55 protein DUF5331 PF17265.2 CDJ52357.1 - 0.2 11.4 3.2 0.17 11.6 1.9 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5331) DUF2380 PF09533.10 CDJ52357.1 - 0.28 10.8 6.9 0.34 10.5 6.9 1.1 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) HA2 PF04408.23 CDJ52357.1 - 0.29 11.4 5.8 0.34 11.2 5.8 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) TMEM208_SND2 PF05620.11 CDJ52357.1 - 2.9 7.6 13.4 0.2 11.4 7.8 1.7 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 RskA PF10099.9 CDJ52357.1 - 5.5 7.3 24.7 15 5.8 24.7 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA PLAC8 PF04749.17 CDJ52358.1 - 3.2 8.8 12.5 22 6.1 12.5 2.6 1 0 0 1 1 1 0 PLAC8 family Actin PF00022.19 CDJ52359.1 - 3.7e-10 39.0 0.0 7.7e-09 34.7 0.0 2.4 1 1 0 1 1 1 1 Actin Chorion_S16 PF05836.12 CDJ52359.1 - 0.091 13.0 3.5 0.23 11.7 3.5 1.6 1 0 0 1 1 1 0 Chorion protein S16 BAF1_ABF1 PF04684.13 CDJ52359.1 - 0.31 10.0 2.5 0.48 9.4 2.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4598 PF15370.6 CDJ52359.1 - 0.37 11.3 4.3 21 5.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) Roughex PF06020.11 CDJ52359.1 - 0.46 9.5 6.4 0.68 9.0 6.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ52359.1 - 1.9 8.1 7.7 4.5 6.8 7.7 1.6 1 0 0 1 1 1 0 Spt20 family JAB PF01398.21 CDJ52360.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cation_ATPase PF13246.6 CDJ52361.1 - 0.0013 18.8 9.9 0.0013 18.8 9.9 4.0 4 1 0 4 4 4 1 Cation transport ATPase (P-type) DUF1700 PF08006.11 CDJ52361.1 - 0.12 11.9 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) PhoLip_ATPase_N PF16209.5 CDJ52363.1 - 0.0002 21.0 0.1 0.00058 19.5 0.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal DUF2722 PF10846.8 CDJ52363.1 - 0.00024 20.2 2.1 0.00024 20.2 2.1 6.6 4 2 2 6 6 6 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52363.1 - 0.0011 18.7 8.6 0.0011 18.7 8.6 6.3 4 1 2 6 6 6 1 Spt20 family RskA PF10099.9 CDJ52363.1 - 0.0021 18.4 23.9 0.0021 18.4 23.9 6.5 4 2 1 5 5 5 2 Anti-sigma-K factor rskA DUF2721 PF11026.8 CDJ52363.1 - 0.036 14.0 0.8 0.036 14.0 0.8 5.4 6 1 0 6 6 6 0 Protein of unknown function (DUF2721) Cytochrom_C_asm PF01578.20 CDJ52363.1 - 0.072 12.9 3.2 0.16 11.7 0.3 2.7 2 0 0 2 2 2 0 Cytochrome C assembly protein PEX11 PF05648.14 CDJ52363.1 - 0.17 11.3 0.0 0.17 11.3 0.0 6.0 5 1 0 5 5 5 0 Peroxisomal biogenesis factor 11 (PEX11) RskA PF10099.9 CDJ52364.1 - 0.0077 16.5 34.8 0.01 16.2 24.0 2.8 2 1 0 2 2 2 2 Anti-sigma-K factor rskA Afi1 PF07792.12 CDJ52364.1 - 0.021 15.3 6.3 0.021 15.3 6.3 3.9 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Hamartin PF04388.12 CDJ52364.1 - 1.1 7.8 46.1 1.9 7.1 46.1 1.3 1 0 0 1 1 1 0 Hamartin protein Vpu PF00558.19 CDJ52365.1 - 0.033 14.0 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 Vpu protein Sas10 PF09368.10 CDJ52366.1 - 1.1e-24 86.7 7.5 1.1e-24 86.7 7.5 3.3 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CDJ52366.1 - 9.6e-18 64.6 0.6 9.6e-18 64.6 0.6 3.5 4 0 0 4 4 4 1 Sas10/Utp3/C1D family RRM_1 PF00076.22 CDJ52368.1 - 3e-16 59.0 0.0 4.1e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ52368.1 - 0.011 15.9 0.0 0.05 13.7 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 CDJ52368.1 - 0.18 11.4 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_28 PF02636.17 CDJ52369.1 - 0.027 14.1 0.4 0.096 12.3 0.5 1.9 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF938 PF06080.12 CDJ52369.1 - 0.099 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Chorion_2 PF03964.15 CDJ52369.1 - 6.4 7.7 12.1 3 8.7 1.9 2.7 2 1 0 2 2 2 0 Chorion family 2 C2 PF00168.30 CDJ52370.1 - 3.4e-10 40.1 0.0 1.4e-08 34.9 0.0 2.7 1 1 0 1 1 1 1 C2 domain Chorion_2 PF03964.15 CDJ52370.1 - 0.0015 19.3 3.2 0.0015 19.3 3.2 6.1 7 1 0 7 7 7 1 Chorion family 2 Transglut_core PF01841.19 CDJ52370.1 - 0.03 14.8 0.2 0.099 13.1 0.2 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF1043 PF06295.12 CDJ52371.1 - 0.00011 22.2 0.2 0.00049 20.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1043) DivIC PF04977.15 CDJ52371.1 - 0.012 15.4 1.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator MerR-DNA-bind PF09278.11 CDJ52371.1 - 0.053 14.1 6.4 0.29 11.7 0.3 2.4 2 0 0 2 2 2 0 MerR, DNA binding DUF2205 PF10224.9 CDJ52371.1 - 0.13 12.3 1.9 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 Short coiled-coil protein Seryl_tRNA_N PF02403.22 CDJ52371.1 - 0.18 12.0 4.9 4 7.7 0.4 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1126 PF06565.12 CDJ52373.1 - 1.4e-15 57.0 0.1 4.8e-10 39.2 0.0 2.6 2 1 0 2 2 2 2 DUF1126 PH-like domain TBP PF00352.21 CDJ52374.1 - 0.024 14.6 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) RNA_pol_Rpb2_6 PF00562.28 CDJ52375.1 - 6.3e-75 252.7 0.2 7.7e-75 252.4 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 CDJ52375.1 - 1.2e-33 115.4 0.4 2e-33 114.6 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 zf-C2H2_6 PF13912.6 CDJ52375.1 - 4.6 7.4 6.6 20 5.3 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Connexin PF00029.19 CDJ52376.1 - 4 7.1 26.6 0.65 9.7 2.4 2.8 3 0 0 3 3 3 0 Connexin AAA_23 PF13476.6 CDJ52376.1 - 4.5 7.7 40.7 0.034 14.7 5.0 2.3 2 0 0 2 2 2 0 AAA domain Spt20 PF12090.8 CDJ52377.1 - 0.034 13.8 94.6 0.23 11.1 27.6 5.2 5 0 0 5 5 5 0 Spt20 family AF-4 PF05110.13 CDJ52379.1 - 0.00096 17.4 33.5 0.00096 17.4 33.5 3.9 1 1 1 3 3 3 1 AF-4 proto-oncoprotein AIM3 PF17096.5 CDJ52379.1 - 0.018 15.9 0.0 0.018 15.9 0.0 5.8 4 2 1 5 5 5 0 Altered inheritance of mitochondria protein 3 Porin_OmpG PF09381.10 CDJ52379.1 - 0.03 14.1 4.8 0.05 13.4 0.6 2.2 2 0 0 2 2 2 0 Outer membrane protein G (OmpG) SART-1 PF03343.13 CDJ52379.1 - 0.097 11.2 20.2 0.043 12.4 8.7 2.6 2 0 0 2 2 2 0 SART-1 family Sporozoite_P67 PF05642.11 CDJ52380.1 - 0.29 9.2 1.8 0.38 8.8 1.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3040 PF11239.8 CDJ52380.1 - 0.6 10.4 9.8 3.3 8.1 7.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Sin_N PF04801.13 CDJ52380.1 - 0.6 9.3 15.8 0.83 8.8 15.8 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region TFIIA PF03153.13 CDJ52380.1 - 0.96 9.4 25.6 0.022 14.8 18.8 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3446 PF11928.8 CDJ52381.1 - 0.011 16.0 3.6 0.011 16.0 3.6 1.9 3 0 0 3 3 3 0 Early growth response N-terminal domain DUF2849 PF11011.8 CDJ52381.1 - 0.11 13.2 0.4 0.11 13.2 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2849) CitMHS PF03600.16 CDJ52382.1 - 1.4e-09 37.6 7.8 1.4e-09 37.6 7.8 3.1 2 1 0 3 3 3 1 Citrate transporter Na_sulph_symp PF00939.19 CDJ52382.1 - 2.6e-09 36.6 25.9 3.2e-06 26.5 26.2 2.8 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Zip PF02535.22 CDJ52382.1 - 7.6e-05 22.1 1.6 0.35 10.0 2.3 2.6 2 0 0 2 2 2 2 ZIP Zinc transporter Band_3_cyto PF07565.13 CDJ52382.1 - 0.00034 20.5 1.0 0.00034 20.5 1.0 2.7 3 0 0 3 3 3 1 Band 3 cytoplasmic domain DDHD PF02862.17 CDJ52382.1 - 0.001 19.3 14.3 0.045 13.9 1.3 3.2 3 0 0 3 3 3 2 DDHD domain Pex14_N PF04695.13 CDJ52382.1 - 0.003 18.2 17.1 0.003 18.2 17.1 4.7 3 1 1 4 4 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.16 CDJ52382.1 - 0.0031 17.6 13.8 0.071 13.2 0.1 3.3 3 0 0 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region BatD PF13584.6 CDJ52382.1 - 0.0035 16.2 4.7 0.0035 16.2 4.7 3.6 5 0 0 5 5 5 1 Oxygen tolerance DUF2207 PF09972.9 CDJ52382.1 - 0.081 11.7 0.0 0.081 11.7 0.0 2.6 4 0 0 4 4 3 0 Predicted membrane protein (DUF2207) Velvet PF11754.8 CDJ52382.1 - 0.2 11.6 22.9 0.027 14.4 4.5 3.0 3 0 0 3 3 3 0 Velvet factor RskA PF10099.9 CDJ52382.1 - 0.37 11.1 0.0 0.37 11.1 0.0 7.4 4 2 3 8 8 5 0 Anti-sigma-K factor rskA PIP5K PF01504.18 CDJ52382.1 - 0.43 9.8 12.3 1.9 7.7 0.7 2.5 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF913 PF06025.12 CDJ52382.1 - 0.93 8.4 14.9 0.29 10.1 2.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) DUF2828 PF11443.8 CDJ52382.1 - 3.5 5.6 18.4 0.16 10.0 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) CLN3 PF02487.17 CDJ52382.1 - 6.3 5.7 14.3 5.3 6.0 2.4 2.5 2 0 0 2 2 2 0 CLN3 protein Lin-8 PF03353.15 CDJ52382.1 - 7.9 5.9 36.7 0.042 13.4 7.5 3.2 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist IHABP4_N PF16174.5 CDJ52383.1 - 8.2 7.0 33.4 9.3 6.8 33.4 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal CCSAP PF15748.5 CDJ52384.1 - 0.0037 17.5 19.2 0.0037 17.5 19.2 3.0 3 0 0 3 3 3 1 Centriole, cilia and spindle-associated YppG PF14179.6 CDJ52384.1 - 3.1 8.6 21.2 2.6 8.8 1.4 2.8 2 0 0 2 2 2 0 YppG-like protein SLC12 PF03522.15 CDJ52384.1 - 6.3 5.7 6.0 9.8 5.1 6.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 GTP_EFTU PF00009.27 CDJ52385.1 - 3.6e-18 65.8 0.0 7.3e-17 61.5 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ52385.1 - 0.00014 21.9 0.0 0.059 13.5 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDJ52385.1 - 0.16 12.0 0.0 0.16 12.0 0.0 2.8 3 1 0 3 3 3 0 Dynamin family SelP_N PF04592.14 CDJ52386.1 - 0.00022 20.7 2.6 0.00022 20.7 2.6 5.8 6 0 0 6 6 6 1 Selenoprotein P, N terminal region DUF2722 PF10846.8 CDJ52386.1 - 0.00035 19.6 0.3 0.00035 19.6 0.3 14.7 13 3 1 14 14 14 4 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ52386.1 - 0.00036 20.9 0.6 0.00036 20.9 0.6 25.4 8 7 11 19 19 19 2 Anti-sigma-K factor rskA Sporozoite_P67 PF05642.11 CDJ52386.1 - 0.00047 18.4 7.7 0.00047 18.4 7.7 4.5 4 1 0 4 4 4 1 Sporozoite P67 surface antigen Spt20 PF12090.8 CDJ52386.1 - 0.00098 18.8 2.4 0.00098 18.8 2.4 16.4 15 4 0 16 16 16 3 Spt20 family TFIIA PF03153.13 CDJ52386.1 - 0.0022 18.1 32.0 0.0022 18.1 32.0 12.7 5 3 4 10 10 10 2 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ52386.1 - 0.0051 17.8 0.7 0.0051 17.8 0.7 12.1 11 2 0 11 11 11 2 Domain of unknown function (DUF4834) DS PF01916.17 CDJ52387.1 - 1.8e-90 303.1 0.0 4.8e-90 301.7 0.0 1.7 1 1 0 1 1 1 1 Deoxyhypusine synthase Pex14_N PF04695.13 CDJ52387.1 - 0.00052 20.7 18.0 0.00052 20.7 18.0 4.8 4 1 0 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5427 PF10310.9 CDJ52387.1 - 0.0015 17.6 13.1 0.0015 17.6 13.1 3.9 4 0 0 4 4 4 1 Family of unknown function (DUF5427) Histone_HNS PF00816.21 CDJ52387.1 - 0.022 15.5 3.4 0.022 15.5 3.4 5.1 6 0 0 6 6 6 0 H-NS histone family Filament_head PF04732.14 CDJ52387.1 - 0.8 10.6 37.3 0.32 11.9 7.1 3.7 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region Dicty_REP PF05086.12 CDJ52387.1 - 3 5.7 14.5 6.1 4.7 14.5 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TLP-20 PF06088.11 CDJ52387.1 - 6 6.7 14.4 0.33 10.8 4.7 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Ecl1 PF12855.7 CDJ52387.1 - 9.3 7.4 56.0 3.5 8.8 7.5 3.3 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins AAA PF00004.29 CDJ52388.1 - 4.8e-16 59.4 21.6 1.6e-08 35.0 1.7 5.4 4 1 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ52388.1 - 1.2e-07 31.6 0.0 0.034 13.9 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ52388.1 - 3.7e-06 27.0 0.5 0.044 13.8 0.1 3.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CDJ52388.1 - 1e-05 25.1 0.4 0.12 11.7 0.1 3.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CDJ52388.1 - 1.7e-05 24.6 0.0 0.048 13.4 0.0 3.2 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 CDJ52388.1 - 4.7e-05 23.7 0.0 0.12 12.8 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AFG1_ATPase PF03969.16 CDJ52388.1 - 0.00015 20.8 0.7 0.00015 20.8 0.7 3.8 5 0 0 5 5 3 1 AFG1-like ATPase AAA_lid_3 PF17862.1 CDJ52388.1 - 0.00017 21.3 0.1 0.00041 20.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_7 PF12775.7 CDJ52388.1 - 0.00021 20.8 2.0 1.2 8.6 0.0 3.3 2 1 1 3 3 3 2 P-loop containing dynein motor region Rad17 PF03215.15 CDJ52388.1 - 0.0003 20.8 0.1 0.27 11.1 0.1 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_22 PF13401.6 CDJ52388.1 - 0.00056 20.2 13.3 0.023 15.0 0.3 4.8 3 1 1 4 4 3 1 AAA domain AAA_3 PF07726.11 CDJ52388.1 - 0.0013 18.6 0.1 1.1 9.1 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CDJ52388.1 - 0.0014 18.6 0.0 0.51 10.4 0.0 2.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CDJ52388.1 - 0.0023 18.3 0.2 0.0023 18.3 0.2 3.0 3 1 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 CDJ52388.1 - 0.011 15.7 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 CDJ52388.1 - 0.013 15.3 5.3 0.071 12.9 0.0 3.4 4 1 0 5 5 4 0 Bacterial dnaA protein NAM-associated PF14303.6 CDJ52388.1 - 0.044 14.5 0.0 0.044 14.5 0.0 6.0 3 2 1 4 4 2 0 No apical meristem-associated C-terminal domain TIP49 PF06068.13 CDJ52388.1 - 0.05 12.8 0.0 4.9 6.3 0.0 2.4 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_14 PF13173.6 CDJ52388.1 - 0.1 12.6 1.4 7.7 6.6 0.0 4.1 4 1 1 5 5 4 0 AAA domain AAA_25 PF13481.6 CDJ52388.1 - 0.12 12.0 4.7 2.4 7.7 0.1 3.5 3 1 1 4 4 4 0 AAA domain AAA_24 PF13479.6 CDJ52388.1 - 0.12 12.1 0.1 0.12 12.1 0.1 4.8 4 2 1 5 5 4 0 AAA domain AAA_16 PF13191.6 CDJ52388.1 - 0.14 12.6 0.0 0.012 16.0 11.5 5.8 2 1 3 5 5 3 0 AAA ATPase domain AAA_18 PF13238.6 CDJ52388.1 - 1.4 9.5 0.0 1.4 9.5 0.0 4.2 4 2 0 4 4 3 0 AAA domain DUF3742 PF12553.8 CDJ52388.1 - 1.8 8.7 5.1 13 5.9 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3742) Endomucin PF07010.12 CDJ52389.1 - 0.18 11.7 0.1 0.21 11.5 0.1 1.0 1 0 0 1 1 1 0 Endomucin LCE6A PF15858.5 CDJ52389.1 - 1.8 9.4 4.2 2.1 9.1 3.5 1.6 1 1 0 1 1 1 0 Late cornified envelope protein 6A family DUF1180 PF06679.12 CDJ52389.1 - 5.4 7.4 9.3 7.2 7.0 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GREB1 PF15782.5 CDJ52391.1 - 7.1 3.6 27.0 9.4 3.2 27.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NPR3 PF03666.13 CDJ52392.1 - 0.0038 16.1 32.7 0.0045 15.9 32.7 1.0 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF4045 PF13254.6 CDJ52392.1 - 0.68 9.5 30.9 0.67 9.5 30.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SRP-alpha_N PF04086.13 CDJ52392.1 - 0.85 9.5 29.9 1 9.2 29.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ASC PF00858.24 CDJ52392.1 - 0.92 8.4 18.2 1.1 8.2 18.2 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Lin-8 PF03353.15 CDJ52392.1 - 1.6 8.2 39.5 1.9 8.0 39.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MCM_bind PF09739.9 CDJ52392.1 - 1.7 7.0 32.5 2.1 6.7 32.5 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor HCO3_cotransp PF00955.21 CDJ52392.1 - 2.1 7.0 19.0 2.6 6.8 19.0 1.0 1 0 0 1 1 1 0 HCO3- transporter family Presenilin PF01080.17 CDJ52392.1 - 2.9 6.6 47.0 3.6 6.3 47.0 1.0 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 CDJ52392.1 - 2.9 6.5 28.9 3.5 6.3 28.9 1.0 1 0 0 1 1 1 0 Raftlin RR_TM4-6 PF06459.12 CDJ52392.1 - 3.1 7.6 42.6 3.5 7.4 42.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 CDJ52392.1 - 3.4 6.8 28.4 4.1 6.5 28.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.9 CDJ52392.1 - 3.6 5.7 59.3 3.7 5.7 59.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.9 CDJ52392.1 - 4 6.2 25.5 4.5 6.0 25.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CAC1F_C PF16885.5 CDJ52392.1 - 4.1 7.0 24.3 4.8 6.7 24.3 1.0 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term AF-4 PF05110.13 CDJ52392.1 - 4.7 5.2 40.8 5 5.1 40.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Hydin_ADK PF17213.3 CDJ52392.1 - 4.7 7.4 29.1 6.7 6.9 29.1 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain WTX PF09422.10 CDJ52392.1 - 5 6.1 25.4 5.2 6.0 25.4 1.0 1 0 0 1 1 1 0 WTX protein FAM60A PF15396.6 CDJ52392.1 - 5 7.1 34.0 6.4 6.7 34.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Rtf2 PF04641.12 CDJ52392.1 - 5.7 6.2 36.7 7.5 5.8 36.7 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger ALMT PF11744.8 CDJ52392.1 - 6.5 5.5 31.8 8 5.2 31.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Vfa1 PF08432.10 CDJ52392.1 - 6.5 7.0 40.0 7.7 6.8 40.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GREB1 PF15782.5 CDJ52392.1 - 7.5 3.5 36.2 7 3.6 36.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mitofilin PF09731.9 CDJ52393.1 - 6.9e-05 21.9 0.3 6.9e-05 21.9 0.3 3.7 2 1 0 3 3 3 2 Mitochondrial inner membrane protein SR-25 PF10500.9 CDJ52393.1 - 0.0061 16.2 4.9 0.0061 16.2 4.9 7.0 4 3 1 5 5 5 1 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ52393.1 - 0.012 15.6 1.7 0.012 15.6 1.7 8.6 4 2 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 CCSAP PF15748.5 CDJ52393.1 - 0.014 15.6 1.2 0.014 15.6 1.2 5.9 4 2 2 6 6 6 0 Centriole, cilia and spindle-associated GET2 PF08690.10 CDJ52393.1 - 0.017 14.8 0.3 0.017 14.8 0.3 5.1 2 1 3 5 5 5 0 GET complex subunit GET2 DUF4820 PF16091.5 CDJ52395.1 - 0.044 13.2 10.3 0.052 12.9 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CobT PF06213.12 CDJ52395.1 - 0.1 12.0 23.0 0.11 11.9 23.0 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pex14_N PF04695.13 CDJ52395.1 - 0.23 12.1 27.9 0.23 12.1 27.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM174 PF15029.6 CDJ52395.1 - 0.25 11.0 5.3 0.27 10.9 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 174 SpoIIP PF07454.11 CDJ52395.1 - 0.29 10.5 17.6 0.29 10.5 17.6 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PRC2_HTH_1 PF18118.1 CDJ52395.1 - 0.31 11.8 10.5 0.33 11.8 10.5 1.1 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Connexin PF00029.19 CDJ52395.1 - 0.32 10.7 14.6 0.36 10.6 14.6 1.0 1 0 0 1 1 1 0 Connexin DUF2072 PF09845.9 CDJ52395.1 - 0.41 10.9 10.1 0.41 10.9 10.1 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein Serinc PF03348.15 CDJ52395.1 - 0.48 9.3 8.4 0.42 9.5 8.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) CPSF100_C PF13299.6 CDJ52395.1 - 0.5 10.5 12.3 0.48 10.6 12.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CDJ52395.1 - 0.56 8.9 18.5 0.55 8.9 18.5 1.0 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 CDJ52395.1 - 0.56 10.3 14.4 0.56 10.3 14.4 1.1 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ52395.1 - 0.66 8.9 23.3 0.63 8.9 23.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Velvet PF11754.8 CDJ52395.1 - 0.73 9.7 16.4 0.76 9.7 16.4 1.0 1 0 0 1 1 1 0 Velvet factor RR_TM4-6 PF06459.12 CDJ52395.1 - 0.88 9.3 14.9 0.86 9.4 14.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 CDJ52395.1 - 0.9 7.4 17.8 0.96 7.3 17.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC53 PF10152.9 CDJ52395.1 - 1.4 9.4 17.5 1.4 9.3 17.5 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex UPF0239 PF06783.11 CDJ52395.1 - 1.5 9.1 9.1 1.9 8.7 9.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) G0-G1_switch_2 PF15103.6 CDJ52395.1 - 1.7 9.1 12.2 2 8.9 12.2 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 Gti1_Pac2 PF09729.9 CDJ52395.1 - 2 8.5 13.1 2 8.4 13.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family FAM60A PF15396.6 CDJ52395.1 - 2.3 8.2 12.0 2.3 8.2 12.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.9 CDJ52395.1 - 2.5 6.3 28.2 2.4 6.3 28.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CSG2 PF16965.5 CDJ52395.1 - 2.5 6.9 10.0 2.8 6.8 10.0 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator FHIPEP PF00771.20 CDJ52395.1 - 2.9 6.3 10.8 3.2 6.1 10.8 1.1 1 0 0 1 1 1 0 FHIPEP family Band_3_cyto PF07565.13 CDJ52395.1 - 2.9 7.6 17.3 3 7.6 17.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM176 PF14851.6 CDJ52395.1 - 3 7.5 12.2 3.6 7.3 12.2 1.1 1 0 0 1 1 1 0 FAM176 family DUF913 PF06025.12 CDJ52395.1 - 3.1 6.7 10.7 2.9 6.8 10.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_23 PF13476.6 CDJ52395.1 - 3.1 8.2 20.3 3.1 8.2 20.3 1.1 1 0 0 1 1 1 0 AAA domain Ureide_permease PF07168.11 CDJ52395.1 - 3.2 6.4 9.1 3.6 6.2 9.1 1.0 1 0 0 1 1 1 0 Ureide permease Tim54 PF11711.8 CDJ52395.1 - 3.3 6.4 15.2 3.6 6.3 15.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4407 PF14362.6 CDJ52395.1 - 3.6 6.9 19.9 3.3 7.0 19.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SID-1_RNA_chan PF13965.6 CDJ52395.1 - 4.1 5.7 10.0 4.4 5.6 10.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIA PF03153.13 CDJ52395.1 - 4.4 7.2 44.3 4.4 7.2 44.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPL5 PF18168.1 CDJ52395.1 - 4.7 6.4 12.6 5.1 6.3 12.6 1.0 1 0 0 1 1 1 0 Prim-pol family 5 CLN3 PF02487.17 CDJ52395.1 - 5.2 6.0 14.5 5.6 5.9 14.5 1.0 1 0 0 1 1 1 0 CLN3 protein DUF2828 PF11443.8 CDJ52395.1 - 5.7 4.9 17.3 6 4.8 17.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Peroxin-13_N PF04088.13 CDJ52395.1 - 6.8 7.0 10.5 7.5 6.8 10.5 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4746 PF15928.5 CDJ52395.1 - 7.1 6.0 13.3 7.5 5.9 13.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) EOS1 PF12326.8 CDJ52395.1 - 7.1 6.5 11.6 7.5 6.4 11.6 1.1 1 0 0 1 1 1 0 N-glycosylation protein AIF_C PF14721.6 CDJ52395.1 - 7.7 6.9 15.2 8.8 6.7 15.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PIP5K PF01504.18 CDJ52395.1 - 8.3 5.5 17.3 9 5.4 17.3 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase OATP PF03137.20 CDJ52395.1 - 8.5 4.5 10.8 9.1 4.4 10.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SLC12 PF03522.15 CDJ52395.1 - 8.7 5.2 18.2 9.4 5.1 18.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S49_N PF08496.10 CDJ52395.1 - 9.5 6.3 16.3 10 6.2 16.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.16 CDJ52395.1 - 9.6 6.2 14.3 9.4 6.2 14.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Caldesmon PF02029.15 CDJ52396.1 - 3.2e-06 26.2 46.6 3.2e-06 26.2 46.6 2.1 2 0 0 2 2 2 2 Caldesmon RskA PF10099.9 CDJ52397.1 - 0.16 12.3 27.1 3.8 7.8 27.1 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ52397.1 - 0.52 10.3 14.3 0.58 10.1 14.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med22 PF06179.12 CDJ52398.1 - 9.6e-06 25.8 0.1 1.2e-05 25.4 0.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Radial_spoke_3 PF06098.11 CDJ52399.1 - 1.8e-34 119.3 12.3 6.2e-34 117.6 3.9 2.6 3 0 0 3 3 3 2 Radial spoke protein 3 TAXi_C PF14541.6 CDJ52399.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal TFIIA PF03153.13 CDJ52399.1 - 8.7 6.2 10.2 3.5 7.5 3.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TMEM51 PF15345.6 CDJ52400.1 - 1.4 8.7 10.4 3 7.6 0.1 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 ANAPC_CDC26 PF10471.9 CDJ52400.1 - 1.7 9.6 22.7 0.33 11.8 10.6 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CDJ52400.1 - 3.8 7.1 29.0 7.4 6.1 21.1 2.1 2 0 0 2 2 2 0 Spt20 family WBP-1 PF11669.8 CDJ52400.1 - 9.2 7.0 6.8 31 5.3 2.2 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 Trypsin PF00089.26 CDJ52403.1 - 0.007 16.2 3.2 0.01 15.7 3.2 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CDJ52403.1 - 0.045 14.7 0.0 0.045 14.7 0.0 1.9 2 1 0 2 2 2 0 Trypsin-like peptidase domain RskA PF10099.9 CDJ52403.1 - 6.7 7.0 26.7 0.95 9.7 0.4 2.8 2 1 0 2 2 2 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ52404.1 - 8.6e-06 26.2 11.1 1.2e-05 25.7 11.1 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA ANAPC_CDC26 PF10471.9 CDJ52404.1 - 0.046 14.5 18.0 0.076 13.9 18.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 SARAF PF06682.12 CDJ52404.1 - 0.047 13.3 10.2 0.056 13.1 10.2 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis BAF1_ABF1 PF04684.13 CDJ52404.1 - 0.059 12.4 6.6 0.07 12.2 6.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.8 CDJ52404.1 - 0.077 12.6 16.6 0.097 12.3 16.6 1.2 1 0 0 1 1 1 0 Spt20 family SRP-alpha_N PF04086.13 CDJ52404.1 - 0.13 12.1 8.3 0.16 11.9 8.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TFIIA PF03153.13 CDJ52404.1 - 0.17 11.9 18.5 0.18 11.7 18.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ52404.1 - 0.25 10.9 7.1 0.27 10.7 7.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PepSY_2 PF13670.6 CDJ52404.1 - 0.41 10.7 12.0 0.19 11.7 6.9 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain PNISR PF15996.5 CDJ52404.1 - 0.41 10.9 13.3 0.56 10.5 13.3 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Neur_chan_memb PF02932.16 CDJ52404.1 - 0.56 10.2 3.7 0.7 9.9 3.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 CDJ52404.1 - 0.59 8.9 5.9 0.64 8.8 5.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Methyltransf_34 PF11312.8 CDJ52404.1 - 1 8.5 5.9 1.3 8.1 5.9 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase eIF-3_zeta PF05091.12 CDJ52404.1 - 1.4 7.8 10.1 1.6 7.6 10.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.13 CDJ52404.1 - 1.5 8.6 4.3 1.8 8.3 4.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ52404.1 - 1.8 7.3 10.3 2 7.1 10.3 1.1 1 0 0 1 1 1 0 Presenilin API5 PF05918.11 CDJ52404.1 - 4.4 6.0 10.1 5.5 5.7 10.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Plasmodium_Vir PF05795.11 CDJ52404.1 - 4.5 6.6 7.5 5.1 6.4 7.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NPR3 PF03666.13 CDJ52404.1 - 5.4 5.7 9.8 6.6 5.4 9.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CCDC106 PF15794.5 CDJ52404.1 - 5.8 6.6 13.1 7.5 6.2 13.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SPX PF03105.19 CDJ52406.1 - 4.3e-05 23.6 0.0 8e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 SPX domain Nha1_C PF08619.10 CDJ52406.1 - 0.034 13.4 10.9 0.34 10.1 1.0 2.3 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Apt1 PF10351.9 CDJ52406.1 - 0.22 10.3 9.8 0.067 12.0 3.5 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain zf-C3HC4_3 PF13920.6 CDJ52406.1 - 0.33 10.9 24.9 0.11 12.3 21.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BAF1_ABF1 PF04684.13 CDJ52406.1 - 0.38 9.8 11.2 0.87 8.6 1.6 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor AF-4 PF05110.13 CDJ52406.1 - 2 6.4 26.0 0.013 13.6 10.7 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DUF4692 PF15763.5 CDJ52406.1 - 2.3 8.6 14.3 0.35 11.3 8.9 2.2 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) SR-25 PF10500.9 CDJ52406.1 - 5.9 6.4 25.0 0.024 14.3 13.0 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein WD40 PF00400.32 CDJ52408.1 - 6.7e-06 26.8 1.2 0.072 14.0 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4667 PF15700.5 CDJ52408.1 - 0.077 13.1 2.9 0.9 9.6 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ52408.1 - 0.94 9.4 20.9 1.4 8.8 15.2 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ52408.1 - 3.2 6.6 13.0 0.024 13.6 4.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF1645 PF07816.11 CDJ52408.1 - 5.3 7.6 14.0 0.15 12.6 1.5 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ52412.1 - 0.0092 15.6 13.5 0.0092 15.6 13.5 4.5 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Phage_Mu_Gp45 PF06890.12 CDJ52414.1 - 0.028 14.1 1.3 0.076 12.8 1.3 1.7 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein DUF45 PF01863.17 CDJ52414.1 - 1.2 9.1 6.8 0.41 10.7 3.9 1.7 1 1 1 2 2 2 0 Protein of unknown function DUF45 DUF5321 PF17254.2 CDJ52414.1 - 4.3 6.7 13.2 0.69 9.3 8.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5321) DUF2722 PF10846.8 CDJ52414.1 - 5.4 5.8 15.2 1.1 8.2 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF2681 PF10883.8 CDJ52414.1 - 10 6.6 0.0 10 6.6 0.0 4.3 3 2 0 3 3 3 0 Protein of unknown function (DUF2681) TatD_DNase PF01026.21 CDJ52415.1 - 5.8e-44 150.4 0.0 9.6e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase Spt20 PF12090.8 CDJ52415.1 - 5.7e-05 22.8 26.4 0.0022 17.7 15.1 2.5 2 0 0 2 2 2 2 Spt20 family RskA PF10099.9 CDJ52415.1 - 0.00045 20.6 20.6 0.00045 20.6 20.6 3.2 2 1 0 2 2 2 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ52415.1 - 0.0011 19.0 0.1 0.0011 19.0 0.1 4.7 3 2 1 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 DUF4614 PF15391.6 CDJ52415.1 - 9.9 6.1 25.0 1.5 8.8 7.6 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) Pkinase PF00069.25 CDJ52418.1 - 3.6e-09 36.4 0.1 4.4e-06 26.2 0.0 3.9 4 0 0 4 4 4 2 Protein kinase domain DUF2722 PF10846.8 CDJ52418.1 - 0.00048 19.2 0.9 0.00048 19.2 0.9 6.5 4 3 1 5 5 5 1 Protein of unknown function (DUF2722) DUF3464 PF11947.8 CDJ52418.1 - 0.049 13.4 0.0 0.049 13.4 0.0 5.6 5 1 0 5 5 5 0 Photosynthesis affected mutant 68 DUF1645 PF07816.11 CDJ52419.1 - 6.2e-05 23.7 9.5 6.2e-05 23.7 9.5 5.5 3 1 0 4 4 4 1 Protein of unknown function (DUF1645) Med3 PF11593.8 CDJ52419.1 - 0.00014 21.2 12.1 0.00014 21.2 12.1 4.6 2 1 2 4 4 4 1 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ52419.1 - 0.014 15.7 10.2 0.014 15.7 10.2 4.4 2 1 2 4 4 4 0 Anti-sigma-K factor rskA Nitr_red_alph_N PF14710.6 CDJ52419.1 - 0.088 13.3 0.0 0.27 11.7 0.0 1.9 1 0 0 1 1 1 0 Respiratory nitrate reductase alpha N-terminal Methyltransf_11 PF08241.12 CDJ52421.1 - 1.4e-05 25.6 0.0 8.1e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ52421.1 - 5.9e-05 23.7 0.4 0.0002 22.0 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ52421.1 - 0.00012 21.9 0.0 0.00057 19.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ52421.1 - 0.0018 18.9 0.0 0.005 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Sporozoite_P67 PF05642.11 CDJ52421.1 - 3.4 5.6 7.6 0.071 11.2 1.3 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF515 PF04415.12 CDJ52421.1 - 3.6 5.9 7.0 5 5.4 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.9 CDJ52421.1 - 10 5.7 18.6 20 4.7 18.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ52422.1 - 0.00012 22.3 19.5 0.00012 22.3 19.5 4.8 4 1 1 5 5 2 1 Domain of unknown function (DUF755) Spt20 PF12090.8 CDJ52422.1 - 0.00027 20.6 11.2 0.00027 20.6 11.2 4.8 4 1 1 5 5 2 2 Spt20 family CDC45 PF02724.14 CDJ52422.1 - 0.0013 17.1 10.5 0.0013 17.1 10.5 3.1 3 0 0 3 3 3 2 CDC45-like protein AF-4 PF05110.13 CDJ52422.1 - 0.0019 16.4 75.6 0.0033 15.6 16.8 2.3 2 0 0 2 2 2 2 AF-4 proto-oncoprotein K_channel_TID PF07941.11 CDJ52422.1 - 0.0076 16.7 4.5 0.0076 16.7 4.5 7.8 7 1 0 7 7 3 2 Potassium channel Kv1.4 tandem inactivation domain RIFIN PF02009.16 CDJ52422.1 - 0.0093 15.9 5.2 0.0093 15.9 5.2 3.3 3 0 0 3 3 3 1 Rifin TAF4 PF05236.14 CDJ52422.1 - 0.024 14.4 0.3 0.024 14.4 0.3 3.8 3 1 0 4 4 1 0 Transcription initiation factor TFIID component TAF4 family DUF913 PF06025.12 CDJ52422.1 - 0.051 12.6 30.7 0.19 10.7 9.5 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 CDJ52422.1 - 0.15 10.8 29.6 0.007 15.2 11.5 3.0 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein Cwf_Cwc_15 PF04889.12 CDJ52422.1 - 0.39 10.4 45.6 2.1 8.0 6.3 3.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF4407 PF14362.6 CDJ52422.1 - 0.58 9.5 41.6 0.014 14.7 14.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Lin-8 PF03353.15 CDJ52422.1 - 2 7.9 69.1 0.033 13.8 11.8 3.1 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist BORG_CEP PF14957.6 CDJ52422.1 - 2 9.6 48.1 1.2 10.3 5.8 3.4 3 0 0 3 3 3 0 Cdc42 effector PNISR PF15996.5 CDJ52422.1 - 2.4 8.4 59.9 0.15 12.3 26.3 3.3 3 0 0 3 3 3 0 Arginine/serine-rich protein PNISR MAP7 PF05672.11 CDJ52422.1 - 3.5 7.3 71.9 5.5 6.7 51.1 3.3 3 0 0 3 3 3 0 MAP7 (E-MAP-115) family Plasmodium_Vir PF05795.11 CDJ52422.1 - 3.6 6.9 30.6 0.49 9.8 7.0 3.1 3 0 0 3 3 3 0 Plasmodium vivax Vir protein PTPRCAP PF15713.5 CDJ52422.1 - 7 6.9 46.7 1.5 9.1 2.7 3.5 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated Tim54 PF11711.8 CDJ52422.1 - 7.9 5.2 31.5 0.14 10.9 15.4 3.1 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 CDJ52422.1 - 9.7 6.3 37.7 6.2 7.0 2.2 3.6 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Cwf_Cwc_15 PF04889.12 CDJ52423.1 - 0.34 10.6 36.9 0.099 12.4 11.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2722 PF10846.8 CDJ52424.1 - 8.3e-05 21.7 10.7 8.3e-05 21.7 10.7 30.8 24 8 3 27 27 27 6 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52424.1 - 9.1e-05 22.2 16.6 9.1e-05 22.2 16.6 30.1 20 6 5 25 25 25 8 Spt20 family RskA PF10099.9 CDJ52424.1 - 0.015 15.6 0.0 0.015 15.6 0.0 41.2 11 9 17 29 29 29 0 Anti-sigma-K factor rskA DUF359 PF04019.12 CDJ52425.1 - 0.021 14.5 0.4 0.041 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF359) PCYCGC PF13798.6 CDJ52425.1 - 0.79 9.5 6.9 0.16 11.8 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif SMYLE_N PF18615.1 CDJ52425.1 - 1 8.9 16.9 1.1 8.7 16.9 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain BBS2_N PF14781.6 CDJ52425.1 - 1.1 9.2 11.1 0.88 9.5 5.9 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal zf-C2H2_3rep PF18868.1 CDJ52425.1 - 1.5 9.5 12.3 0.25 12.0 2.7 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF4638 PF15472.6 CDJ52425.1 - 6.3 6.5 14.1 7.5 6.2 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF4407 PF14362.6 CDJ52425.1 - 8.2 5.7 25.9 10 5.4 25.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3847 PF12958.7 CDJ52426.1 - 0.31 11.2 12.6 0.41 10.8 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) Androgen_recep PF02166.16 CDJ52426.1 - 0.57 9.0 18.7 0.55 9.0 18.7 1.0 1 0 0 1 1 1 0 Androgen receptor Peptidase_S15 PF02129.18 CDJ52426.1 - 1.4 8.4 5.3 1.5 8.3 5.3 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Fumerase_C PF05683.12 CDJ52426.1 - 1.6 8.0 3.7 1.8 7.8 3.7 1.0 1 0 0 1 1 1 0 Fumarase C-terminus TFIIA PF03153.13 CDJ52426.1 - 7.5 6.4 20.2 8 6.3 20.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ52426.1 - 7.7 5.3 16.1 8.2 5.2 16.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52426.1 - 9.3 5.8 22.5 9.6 5.7 22.5 1.0 1 0 0 1 1 1 0 Spt20 family Snf7 PF03357.21 CDJ52427.1 - 1.5e-06 27.9 28.0 2.8e-05 23.8 8.9 5.2 3 2 2 5 5 5 2 Snf7 DUF4252 PF14060.6 CDJ52427.1 - 0.063 13.2 0.4 0.18 11.7 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Uteroglobin PF01099.17 CDJ52427.1 - 4.4 7.7 10.8 0.12 12.7 2.9 2.6 2 0 0 2 2 2 0 Uteroglobin family Rad9 PF04139.13 CDJ52428.1 - 1.9e-05 24.3 0.1 0.00056 19.4 0.0 2.2 2 0 0 2 2 2 1 Rad9 Spt20 PF12090.8 CDJ52428.1 - 0.0089 15.7 15.2 0.0089 15.7 15.2 3.9 4 0 0 4 4 4 2 Spt20 family SUIM_assoc PF16619.5 CDJ52428.1 - 0.015 15.4 3.9 0.015 15.4 3.9 4.3 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Gly_rich PF12810.7 CDJ52428.1 - 0.19 11.6 7.1 0.041 13.8 0.9 2.7 3 0 0 3 3 3 0 Glycine rich protein Cwf_Cwc_15 PF04889.12 CDJ52428.1 - 0.96 9.1 12.4 0.76 9.5 0.2 3.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF4770 PF15994.5 CDJ52428.1 - 1.5 9.1 9.2 24 5.1 6.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) ADK PF00406.22 CDJ52429.1 - 4.7e-29 101.4 0.4 2.4e-22 79.7 0.0 2.9 3 0 0 3 3 2 2 Adenylate kinase AAA_17 PF13207.6 CDJ52429.1 - 2.8e-23 82.9 0.8 8.7e-17 61.8 0.0 3.2 3 1 0 3 3 2 2 AAA domain DUF812 PF05667.11 CDJ52429.1 - 0.00014 20.9 17.1 0.0002 20.4 17.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) AAA_18 PF13238.6 CDJ52429.1 - 0.00017 22.2 4.7 0.5 10.9 0.0 3.4 2 1 1 3 3 3 2 AAA domain Peptidase_S64 PF08192.11 CDJ52429.1 - 0.0002 20.1 12.2 0.00027 19.6 12.2 1.1 1 0 0 1 1 1 1 Peptidase family S64 UvrD_C PF13361.6 CDJ52429.1 - 0.00023 20.7 0.3 0.00034 20.1 0.3 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain SUIM_assoc PF16619.5 CDJ52429.1 - 0.00054 20.0 0.0 0.00054 20.0 0.0 5.6 3 1 0 3 3 2 1 Unstructured region C-term to UIM in Ataxin3 Macoilin PF09726.9 CDJ52429.1 - 0.00094 17.9 20.6 0.002 16.8 20.6 1.5 1 0 0 1 1 1 1 Macoilin family YlbD_coat PF14071.6 CDJ52429.1 - 0.0018 18.6 17.1 0.0018 18.6 17.1 2.2 2 0 0 2 2 2 1 Putative coat protein DUF948 PF06103.11 CDJ52429.1 - 0.016 15.5 4.8 0.045 14.0 4.8 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 CDJ52429.1 - 0.04 12.8 3.2 0.051 12.5 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Zeta_toxin PF06414.12 CDJ52429.1 - 0.062 12.6 0.1 0.062 12.6 0.1 2.7 3 1 1 4 4 3 0 Zeta toxin DASH_Spc19 PF08287.11 CDJ52429.1 - 0.47 10.3 29.7 0.66 9.8 18.7 2.6 3 0 0 3 3 3 0 Spc19 SPX PF03105.19 CDJ52429.1 - 0.83 9.5 30.6 3.7 7.4 30.6 1.9 1 1 0 1 1 1 0 SPX domain CorA PF01544.18 CDJ52429.1 - 0.95 8.7 8.1 1.8 7.8 8.1 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Rit1_C PF17184.4 CDJ52429.1 - 1.2 8.6 6.3 2 7.8 6.3 1.3 1 0 0 1 1 1 0 Rit1 N-terminal domain UPF0449 PF15136.6 CDJ52429.1 - 1.2 9.6 17.7 1.1 9.8 15.3 2.2 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF4446 PF14584.6 CDJ52429.1 - 1.3 9.0 7.8 2.9 7.8 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Tweety PF04906.13 CDJ52429.1 - 1.4 7.5 12.3 2 7.0 12.3 1.2 1 0 0 1 1 1 0 Tweety Plk4_PB2 PF18409.1 CDJ52429.1 - 1.9 9.2 5.5 5.6 7.7 5.5 1.9 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 XK-related PF09815.9 CDJ52429.1 - 2 7.4 6.2 3 6.8 6.2 1.3 1 0 0 1 1 1 0 XK-related protein FapA PF03961.13 CDJ52429.1 - 2.3 6.7 12.7 3.4 6.2 12.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3452 PF11934.8 CDJ52429.1 - 2.7 7.6 13.0 6 6.4 12.6 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF3452) CENP-O PF09496.10 CDJ52429.1 - 2.9 7.8 14.1 0.44 10.5 10.1 1.7 2 0 0 2 2 1 0 Cenp-O kinetochore centromere component ABC_tran PF00005.27 CDJ52429.1 - 3.7 8.1 11.4 6.4 7.3 0.0 2.6 2 0 0 2 2 1 0 ABC transporter YabA PF06156.13 CDJ52429.1 - 4.9 7.8 20.7 7.5 7.3 18.4 2.4 2 1 0 2 2 2 0 Initiation control protein YabA Fmp27_WPPW PF10359.9 CDJ52429.1 - 7.7 5.2 18.6 0.94 8.3 12.2 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Glutaredoxin2_C PF04399.13 CDJ52429.1 - 8.2 6.3 13.3 48 3.8 13.3 2.1 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain SR-25 PF10500.9 CDJ52429.1 - 8.4 5.9 27.8 0.018 14.7 16.7 2.1 2 0 0 2 2 1 0 Nuclear RNA-splicing-associated protein Borrelia_P83 PF05262.11 CDJ52429.1 - 8.8 4.7 13.4 17 3.7 13.4 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein RskA PF10099.9 CDJ52430.1 - 1.1 9.5 47.4 0.13 12.5 7.6 3.4 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Filament_head PF04732.14 CDJ52430.1 - 4 8.4 40.4 9.2 7.2 10.6 4.3 4 0 0 4 4 4 0 Intermediate filament head (DNA binding) region E_Pc_C PF06752.12 CDJ52431.1 - 0.0049 17.0 39.9 0.0049 17.0 39.9 5.6 5 1 0 5 5 5 1 Enhancer of Polycomb C-terminus RRM_1 PF00076.22 CDJ52433.1 - 9.5e-05 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC_CDC26 PF10471.9 CDJ52433.1 - 0.0041 17.9 8.5 0.0041 17.9 8.5 3.2 2 1 0 2 2 1 1 Anaphase-promoting complex APC subunit CDC26 Limkain-b1 PF11608.8 CDJ52433.1 - 0.01 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 DDHD PF02862.17 CDJ52433.1 - 0.023 14.8 21.8 0.15 12.2 13.8 2.1 2 0 0 2 2 2 0 DDHD domain DUF3402 PF11882.8 CDJ52433.1 - 0.05 12.7 0.2 0.05 12.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) EPL1 PF10513.9 CDJ52433.1 - 0.22 11.9 0.1 0.22 11.9 0.1 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Pal1 PF08316.11 CDJ52433.1 - 1.4 9.6 13.2 0.47 11.2 5.4 2.2 2 0 0 2 2 2 0 Pal1 cell morphology protein Pex14_N PF04695.13 CDJ52433.1 - 1.5 9.5 45.4 0.26 11.9 3.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4228 PF14009.6 CDJ52433.1 - 1.9 8.8 14.5 4.5 7.6 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) RR_TM4-6 PF06459.12 CDJ52433.1 - 4.2 7.1 30.6 1.1 9.0 17.7 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Rtf2 PF04641.12 CDJ52433.1 - 6.3 6.1 25.6 2.4 7.5 13.0 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger eIF-3_zeta PF05091.12 CDJ52433.1 - 8.4 5.2 37.4 0.93 8.4 23.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RIC3 PF15361.6 CDJ52433.1 - 9.9 6.6 20.7 4.8 7.6 2.3 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 OATP PF03137.20 CDJ52435.1 - 4.1e-05 22.1 1.3 4.1e-05 22.1 1.3 2.4 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.13 CDJ52435.1 - 0.4 10.6 40.5 0.21 11.5 19.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ52435.1 - 1.8 8.1 34.2 0.06 13.0 10.5 2.1 2 0 0 2 2 2 0 Spt20 family G0-G1_switch_2 PF15103.6 CDJ52435.1 - 4.7 7.7 11.8 1.2 9.6 0.5 2.8 3 0 0 3 3 3 0 G0/G1 switch protein 2 DUF2722 PF10846.8 CDJ52435.1 - 5.4 5.8 26.7 0.034 13.1 6.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) NifQ PF04891.12 CDJ52435.1 - 7.7 6.9 14.0 1.6 9.1 6.3 2.6 2 0 0 2 2 2 0 NifQ DUF4834 PF16118.5 CDJ52435.1 - 8.7 7.4 12.6 19 6.3 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ52436.1 - 0.00036 19.6 10.5 0.00036 19.6 10.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52436.1 - 0.00037 20.2 15.3 0.00037 20.2 15.3 2.0 2 0 0 2 2 2 1 Spt20 family Macoilin PF09726.9 CDJ52436.1 - 0.048 12.2 4.5 0.068 11.7 4.5 1.3 1 0 0 1 1 1 0 Macoilin family RPA43_OB PF17875.1 CDJ52436.1 - 0.14 12.8 2.8 0.37 11.4 2.8 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Presenilin PF01080.17 CDJ52436.1 - 0.56 8.9 4.8 0.74 8.5 4.8 1.4 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ52436.1 - 1.5 9.8 6.3 2.3 9.2 5.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PAT1 PF09770.9 CDJ52436.1 - 9.3 4.4 16.5 13 3.9 16.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 CDJ52437.1 - 0.016 15.2 15.9 0.02 14.9 15.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Caps_synth_CapC PF14102.6 CDJ52437.1 - 0.061 13.7 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Capsule biosynthesis CapC AAA_23 PF13476.6 CDJ52437.1 - 0.35 11.4 4.6 0.43 11.1 4.6 1.1 1 0 0 1 1 1 0 AAA domain Ribosomal_60s PF00428.19 CDJ52438.1 - 0.0018 18.8 6.8 0.0018 18.8 6.8 5.8 3 1 1 4 4 4 1 60s Acidic ribosomal protein NnrS PF05940.12 CDJ52438.1 - 0.18 11.2 4.7 0.084 12.2 0.5 2.0 2 0 0 2 2 2 0 NnrS protein DUF3522 PF12036.8 CDJ52438.1 - 0.23 11.7 1.2 1.2 9.4 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) Cytochrom_B_C PF00032.17 CDJ52438.1 - 0.29 11.4 0.6 27 5.1 0.1 2.3 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD OAD_gamma PF04277.13 CDJ52438.1 - 0.63 10.7 0.1 0.63 10.7 0.1 6.6 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Caldesmon PF02029.15 CDJ52438.1 - 4 6.1 52.5 5.6 5.6 52.5 1.2 1 0 0 1 1 1 0 Caldesmon T2SSF PF00482.23 CDJ52438.1 - 4.5 7.3 9.3 7.2 6.6 0.1 3.7 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein F PROCN PF08083.11 CDJ52439.1 - 6.5e-222 736.5 8.1 8.6e-222 736.1 8.1 1.2 1 0 0 1 1 1 1 PROCN (NUC071) domain U6-snRNA_bdg PF10596.9 CDJ52439.1 - 2.6e-56 190.0 0.3 5.6e-56 188.9 0.3 1.5 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 RRM_4 PF10598.9 CDJ52439.1 - 3.2e-47 158.8 0.2 8.3e-47 157.5 0.2 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PhetRS_B1 PF18262.1 CDJ52439.1 - 0.17 12.1 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain PRO8NT PF08082.11 CDJ52440.1 - 4.1e-72 241.1 0.3 5.8e-72 240.6 0.3 1.2 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain Adipogenin PF15202.6 CDJ52441.1 - 1.3 9.1 4.1 25 5.0 0.5 2.7 2 0 0 2 2 2 0 Adipogenin MutS_V PF00488.21 CDJ52442.1 - 5.4e-06 26.5 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V BAF1_ABF1 PF04684.13 CDJ52450.1 - 0.027 13.6 28.8 0.39 9.7 16.7 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF572 PF04502.13 CDJ52450.1 - 0.065 12.9 39.8 0.18 11.4 20.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Presenilin PF01080.17 CDJ52450.1 - 0.25 10.1 57.5 0.0093 14.8 26.2 2.5 2 1 1 3 3 3 0 Presenilin SLC12 PF03522.15 CDJ52450.1 - 0.26 10.3 45.6 0.72 8.8 23.8 2.3 2 0 0 2 2 2 0 Solute carrier family 12 Spt20 PF12090.8 CDJ52450.1 - 0.32 10.6 137.8 0.091 12.4 26.4 5.5 5 0 0 5 5 5 0 Spt20 family Peptidase_M56 PF05569.11 CDJ52450.1 - 0.86 8.7 14.4 0.38 9.9 3.3 2.3 2 0 0 2 2 2 0 BlaR1 peptidase M56 Tim54 PF11711.8 CDJ52450.1 - 8.8 5.0 37.7 1.5 7.5 3.1 3.6 4 0 0 4 4 4 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.6 CDJ52451.1 - 0.024 14.3 22.3 0.22 11.2 5.3 3.3 3 0 0 3 3 3 0 FAM176 family Eapp_C PF10238.9 CDJ52451.1 - 0.059 13.4 31.0 0.63 10.1 8.6 3.5 3 0 0 3 3 3 0 E2F-associated phosphoprotein Caldesmon PF02029.15 CDJ52451.1 - 0.24 10.1 32.4 0.23 10.2 23.5 2.2 2 0 0 2 2 2 0 Caldesmon Band_3_cyto PF07565.13 CDJ52451.1 - 0.31 10.8 28.1 1.3 8.8 8.9 3.2 3 0 0 3 3 3 0 Band 3 cytoplasmic domain CPSF100_C PF13299.6 CDJ52451.1 - 0.39 10.9 27.1 2.4 8.3 9.6 3.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal BORG_CEP PF14957.6 CDJ52451.1 - 0.47 11.6 25.6 0.72 11.0 10.3 3.2 3 0 0 3 3 3 0 Cdc42 effector FYDLN_acid PF09538.10 CDJ52451.1 - 0.72 10.6 23.0 2.6 8.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Ctr PF04145.15 CDJ52451.1 - 1.2 9.8 16.2 11 6.6 4.5 3.3 3 0 0 3 3 3 0 Ctr copper transporter family Gti1_Pac2 PF09729.9 CDJ52451.1 - 1.2 9.2 27.7 0.83 9.7 9.4 3.1 3 0 0 3 3 3 0 Gti1/Pac2 family V_ATPase_I PF01496.19 CDJ52451.1 - 1.3 6.9 32.3 2.7 5.8 15.8 3.1 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family HA2 PF04408.23 CDJ52451.1 - 1.7 9.0 16.9 12 6.2 0.3 3.6 3 0 0 3 3 3 0 Helicase associated domain (HA2) SpoIIP PF07454.11 CDJ52451.1 - 1.9 7.9 38.1 0.48 9.8 13.9 3.2 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) UPF0524 PF15823.5 CDJ52451.1 - 2.3 7.6 17.7 4.4 6.6 1.2 3.2 3 0 0 3 3 3 0 UPF0524 of C3orf70 MID_MedPIWI PF18296.1 CDJ52451.1 - 3.7 7.3 31.6 1.5 8.5 12.4 3.1 3 0 0 3 3 3 0 MID domain of medPIWI RNA_pol_Rpc4 PF05132.14 CDJ52451.1 - 4.1 7.8 31.4 3.1 8.2 10.3 3.2 3 0 0 3 3 3 0 RNA polymerase III RPC4 Connexin PF00029.19 CDJ52451.1 - 5.1 6.8 26.1 3.5 7.3 0.9 3.2 3 0 0 3 3 3 0 Connexin DUF2052 PF09747.9 CDJ52451.1 - 6 7.0 37.0 0.54 10.4 12.9 3.2 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) DUF4471 PF14740.6 CDJ52451.1 - 8.9 5.4 24.0 3.2 6.9 8.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4471) Afi1 PF07792.12 CDJ52451.1 - 9.2 6.7 34.4 2 8.9 2.4 3.3 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DEAD PF00270.29 CDJ52452.1 - 8.9e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PAP1 PF08601.10 CDJ52452.1 - 1.5 8.4 10.1 0.061 13.0 0.6 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 AAA_22 PF13401.6 CDJ52453.1 - 0.05 13.9 0.5 0.079 13.2 0.5 1.5 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.9 CDJ52453.1 - 0.51 8.8 28.5 0.64 8.5 28.5 1.1 1 0 0 1 1 1 0 Macoilin family LAP1C PF05609.12 CDJ52453.1 - 1.5 7.9 22.6 1.8 7.6 22.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) AF-4 PF05110.13 CDJ52453.1 - 4.2 5.3 43.1 5.2 5.0 43.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4407 PF14362.6 CDJ52453.1 - 4.3 6.6 8.9 5.5 6.3 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAT1 PF09770.9 CDJ52453.1 - 5.9 5.0 18.2 6.3 4.9 18.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 CDJ52454.1 - 0.29 11.8 31.2 0.34 11.6 31.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cytochrom_B558a PF05038.13 CDJ52454.1 - 0.33 10.5 5.1 0.36 10.4 5.1 1.1 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit BAF1_ABF1 PF04684.13 CDJ52454.1 - 0.4 9.7 14.3 0.49 9.4 14.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SARAF PF06682.12 CDJ52454.1 - 0.44 10.2 15.5 0.47 10.0 15.5 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis RskA PF10099.9 CDJ52454.1 - 0.81 10.0 22.2 6 7.1 22.2 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA TERB2 PF15101.6 CDJ52454.1 - 1.2 9.2 16.3 1.2 9.1 16.3 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spore_coat_CotO PF14153.6 CDJ52454.1 - 2.1 8.3 23.9 2.8 7.8 23.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Connexin PF00029.19 CDJ52454.1 - 2.9 7.6 8.6 3 7.5 8.6 1.1 1 0 0 1 1 1 0 Connexin YscJ_FliF_C PF08345.11 CDJ52454.1 - 3.1 8.1 16.7 3.6 7.9 16.7 1.1 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal eIF-3_zeta PF05091.12 CDJ52454.1 - 3.1 6.7 17.5 3.4 6.6 17.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3408 PF11888.8 CDJ52454.1 - 3.2 7.9 16.6 4.1 7.6 16.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF4175 PF13779.6 CDJ52454.1 - 4 5.2 34.1 4.3 5.1 34.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RP-C_C PF11800.8 CDJ52454.1 - 4.9 7.2 16.7 5.4 7.0 16.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF1980 PF09323.10 CDJ52454.1 - 5.2 6.9 9.7 5.7 6.8 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) TFIIA PF03153.13 CDJ52454.1 - 5.7 6.8 40.8 6.3 6.7 40.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PcfK PF14058.6 CDJ52454.1 - 6.2 7.1 17.3 8.8 6.6 17.3 1.4 1 0 0 1 1 1 0 PcfK-like protein SpoIIP PF07454.11 CDJ52454.1 - 7.4 5.9 14.3 8 5.8 14.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF3450 PF11932.8 CDJ52454.1 - 7.5 5.8 24.4 8.5 5.6 24.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2344 PF10105.9 CDJ52455.1 - 0.23 11.3 1.7 0.4 10.5 1.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Sporozoite_P67 PF05642.11 CDJ52455.1 - 2.6 6.0 8.9 3.1 5.7 8.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIA PF03153.13 CDJ52455.1 - 4.7 7.1 7.0 5.9 6.8 7.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ52456.1 - 0.00072 18.6 18.0 0.00072 18.6 18.0 8.7 5 1 3 9 9 9 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52456.1 - 0.0012 18.5 28.6 0.0012 18.5 28.6 9.5 5 2 3 8 8 8 2 Spt20 family KASH PF10541.9 CDJ52456.1 - 0.38 11.1 2.2 0.98 9.7 2.2 1.7 1 0 0 1 1 1 0 Nuclear envelope localisation domain Myb_DNA-binding PF00249.31 CDJ52458.1 - 2.6e-08 33.9 0.0 5.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SR-25 PF10500.9 CDJ52458.1 - 0.0048 16.5 20.7 0.0048 16.5 20.7 7.4 3 2 4 7 7 7 1 Nuclear RNA-splicing-associated protein SLIDE PF09111.10 CDJ52458.1 - 0.014 15.5 9.0 0.014 15.5 9.0 6.2 3 2 3 6 6 6 0 SLIDE Sin_N PF04801.13 CDJ52459.1 - 5.8e-05 22.5 35.3 5.8e-05 22.5 35.3 3.8 2 2 1 3 3 3 1 Sin-like protein conserved region CDC27 PF09507.10 CDJ52460.1 - 2.2 7.5 46.2 2.4 7.5 46.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 EIF4E-T PF10477.9 CDJ52461.1 - 9.4e-05 21.4 26.8 9.4e-05 21.4 26.8 2.5 1 1 0 2 2 2 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Med15 PF09606.10 CDJ52461.1 - 0.00054 18.8 13.5 0.00054 18.8 13.5 3.2 2 1 1 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal Lin-8 PF03353.15 CDJ52461.1 - 0.00062 19.4 53.9 0.016 14.8 32.1 2.3 2 0 0 2 2 2 2 Ras-mediated vulval-induction antagonist S4 PF01479.25 CDJ52461.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 S4 domain RskA PF10099.9 CDJ52461.1 - 0.023 15.0 1.3 0.023 15.0 1.3 5.5 2 1 2 4 4 4 0 Anti-sigma-K factor rskA SOBP PF15279.6 CDJ52461.1 - 0.62 10.6 45.3 0.96 10.0 30.8 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein PAT1 PF09770.9 CDJ52461.1 - 0.81 7.9 70.8 0.57 8.4 53.0 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF5349 PF17298.2 CDJ52461.1 - 2.8 7.6 73.4 0.16 11.7 18.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5349) TERB2 PF15101.6 CDJ52462.1 - 0.49 10.4 13.3 0.14 12.2 5.6 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Mucin PF01456.17 CDJ52463.1 - 0.34 10.9 12.6 0.45 10.5 12.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Sec3_C PF09763.9 CDJ52463.1 - 1.7 6.9 5.5 1.8 6.8 5.5 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 BSP_II PF05432.11 CDJ52463.1 - 2.3 7.8 21.6 3 7.4 21.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Apt1 PF10351.9 CDJ52463.1 - 2.5 6.9 17.7 3.1 6.6 17.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ52463.1 - 5.6 6.8 21.0 8 6.3 21.0 1.3 1 0 0 1 1 1 0 SPX domain Neur_chan_memb PF02932.16 CDJ52465.1 - 1.3 9.0 4.1 1.4 8.9 4.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3138 PF11336.8 CDJ52465.1 - 1.5 7.4 12.7 3.3 6.2 12.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) CCDC53 PF10152.9 CDJ52465.1 - 1.9 8.9 6.7 2.4 8.6 6.7 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Exonuc_VII_L PF02601.15 CDJ52465.1 - 3.5 7.1 8.3 4.4 6.8 8.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.13 CDJ52465.1 - 7.4 6.5 14.0 10 6.0 14.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rotamase_2 PF13145.6 CDJ52466.1 - 0.064 14.1 0.2 0.064 14.1 0.2 3.1 2 1 1 3 3 3 0 PPIC-type PPIASE domain Ubiq_cyt_C_chap PF03981.12 CDJ52466.1 - 7.1 6.7 5.7 23 5.0 3.0 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone Otopetrin PF03189.13 CDJ52467.1 - 0.22 10.3 1.6 0.25 10.1 1.6 1.3 1 0 0 1 1 1 0 Otopetrin SLC12 PF03522.15 CDJ52467.1 - 3.1 6.7 17.8 0.15 11.1 10.4 2.0 2 0 0 2 2 2 0 Solute carrier family 12 CDC45 PF02724.14 CDJ52467.1 - 4.7 5.4 13.7 0.042 12.2 5.3 1.8 2 0 0 2 2 2 0 CDC45-like protein Glyco_transf_8 PF01501.20 CDJ52468.1 - 1.4e-06 28.1 3.2 1.4e-06 28.1 3.2 3.3 3 1 0 3 3 3 1 Glycosyl transferase family 8 SpoIIP PF07454.11 CDJ52468.1 - 0.0029 17.1 1.2 0.0029 17.1 1.2 4.9 4 1 0 4 4 4 2 Stage II sporulation protein P (SpoIIP) ARF7EP_C PF14949.6 CDJ52468.1 - 0.017 15.7 2.1 0.017 15.7 2.1 5.3 4 1 1 5 5 5 0 ARF7 effector protein C-terminus SART-1 PF03343.13 CDJ52469.1 - 1.4e-59 202.3 75.9 9.2e-31 107.1 60.2 4.4 1 1 2 3 3 3 3 SART-1 family MPP6 PF10175.9 CDJ52470.1 - 5.1e-07 30.3 0.2 7.2e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 M-phase phosphoprotein 6 FTZ PF03867.14 CDJ52470.1 - 0.012 15.2 5.8 0.015 14.9 5.8 1.0 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region K_channel_TID PF07941.11 CDJ52470.1 - 0.014 15.9 6.4 0.014 15.9 6.4 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Spt20 PF12090.8 CDJ52470.1 - 0.042 13.5 5.7 0.045 13.4 5.7 1.1 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ52470.1 - 0.13 11.4 1.4 0.12 11.4 1.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein RskA PF10099.9 CDJ52470.1 - 0.17 12.1 10.1 0.28 11.4 10.1 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Chorion_2 PF03964.15 CDJ52470.1 - 0.33 11.8 12.4 0.064 14.1 6.0 2.0 2 0 0 2 2 2 0 Chorion family 2 TFIIA PF03153.13 CDJ52470.1 - 0.45 10.5 9.8 0.54 10.2 9.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cyt-b5 PF00173.28 CDJ52471.1 - 2.5e-09 37.1 0.0 4.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2722 PF10846.8 CDJ52471.1 - 0.00048 19.2 4.4 0.00048 19.2 4.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ52471.1 - 0.018 15.0 29.5 0.26 11.2 11.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.9 CDJ52471.1 - 0.025 14.6 16.7 0.025 14.6 16.7 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) EPL1 PF10513.9 CDJ52471.1 - 0.033 14.6 3.5 0.52 10.7 0.2 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Med15 PF09606.10 CDJ52471.1 - 0.075 11.7 35.6 0.13 10.9 12.2 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ52471.1 - 0.71 9.4 35.3 1.6 8.3 19.2 2.2 2 0 0 2 2 2 0 Spt20 family CNDH2_M PF16869.5 CDJ52471.1 - 0.85 10.3 5.7 1.9 9.2 1.4 2.3 2 0 0 2 2 2 0 PF16858 Spt20 PF12090.8 CDJ52472.1 - 0.004 16.8 15.1 0.0089 15.7 15.1 1.5 1 0 0 1 1 1 1 Spt20 family Hid1 PF12722.7 CDJ52472.1 - 0.39 8.8 7.9 0.49 8.5 7.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.14 CDJ52472.1 - 0.57 10.1 6.0 1 9.3 6.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Gti1_Pac2 PF09729.9 CDJ52472.1 - 0.66 10.0 10.5 0.54 10.3 4.9 2.8 3 0 0 3 3 3 0 Gti1/Pac2 family TFIIA PF03153.13 CDJ52472.1 - 1.7 8.5 22.2 2.4 8.1 22.2 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 CDJ52472.1 - 4.3 6.1 5.8 6.7 5.4 5.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Roughex PF06020.11 CDJ52472.1 - 8.8 5.3 8.0 15 4.6 8.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Kinesin PF00225.23 CDJ52473.1 - 9.3e-22 77.4 9.6 9.3e-22 77.4 9.6 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ52473.1 - 1.7e-11 44.3 1.2 1.7e-11 44.3 1.2 4.2 4 1 0 4 4 4 1 Microtubule binding Spt20 PF12090.8 CDJ52474.1 - 0.0013 18.4 30.7 0.0034 17.0 10.0 4.0 3 1 1 4 4 4 2 Spt20 family TrkA_C PF02080.21 CDJ52474.1 - 0.0078 16.0 1.9 4.3 7.2 0.3 4.0 1 1 2 3 3 3 2 TrkA-C domain Pet20 PF08692.10 CDJ52474.1 - 0.87 10.3 0.0 0.87 10.3 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial protein Pet20 DUF2722 PF10846.8 CDJ52474.1 - 8.4 5.2 49.3 0.021 13.8 6.9 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2722) ANAPC8 PF04049.13 CDJ52476.1 - 0.0073 16.4 2.3 0.017 15.2 2.3 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 Toxin_22 PF08092.11 CDJ52476.1 - 0.11 12.6 0.7 0.11 12.6 0.7 2.1 3 0 0 3 3 3 0 Magi peptide toxin family LSM PF01423.22 CDJ52477.1 - 6.5e-10 38.6 0.2 1.5e-08 34.2 0.2 2.2 2 0 0 2 2 2 1 LSM domain DUF4230 PF14014.6 CDJ52477.1 - 0.02 15.2 0.3 0.025 14.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) 2OG-FeII_Oxy_5 PF13759.6 CDJ52477.1 - 0.14 12.6 0.2 0.3 11.5 0.2 1.7 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase SGS PF05002.15 CDJ52477.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 SGS domain tRNA-synt_2b PF00587.25 CDJ52478.1 - 1.2e-08 35.2 0.3 1.5e-05 25.0 0.0 2.6 1 1 1 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) B9-C2 PF07162.11 CDJ52478.1 - 1.2e-06 28.8 0.0 1.2e-06 28.8 0.0 2.3 3 0 0 3 3 3 1 Ciliary basal body-associated, B9 protein Pex14_N PF04695.13 CDJ52478.1 - 0.31 11.7 67.9 0.33 11.6 0.2 4.2 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sin_N PF04801.13 CDJ52478.1 - 1.4 8.0 58.7 5.3 6.2 0.1 2.4 2 0 0 2 2 2 0 Sin-like protein conserved region SARAF PF06682.12 CDJ52478.1 - 2 8.0 32.7 0.18 11.4 22.4 2.4 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis RPN7 PF10602.9 CDJ52480.1 - 7.2e-10 38.9 5.4 1.8e-05 24.5 0.0 2.2 1 1 1 2 2 2 2 26S proteasome subunit RPN7 PRP9_N PF16958.5 CDJ52480.1 - 0.0059 16.7 2.4 0.0078 16.2 2.4 1.1 1 0 0 1 1 1 1 Pre-mRNA-splicing factor PRP9 N-terminus DUF4375 PF14300.6 CDJ52480.1 - 0.13 12.5 2.8 0.2 12.0 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) ARGLU PF15346.6 CDJ52480.1 - 0.19 11.6 10.0 0.27 11.1 10.0 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 RNA_pol_L PF01193.24 CDJ52481.1 - 6.4e-11 41.5 0.0 7.9e-11 41.2 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 CDJ52481.1 - 1.3e-08 35.2 3.8 3.1e-05 24.3 0.1 3.0 1 1 2 3 3 3 2 RNA polymerase Rpb3/RpoA insert domain SR-25 PF10500.9 CDJ52481.1 - 0.004 16.8 27.1 0.017 14.7 8.0 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ52481.1 - 0.01 16.4 6.4 0.01 16.4 6.4 2.6 2 1 0 2 2 2 0 TCP family transcription factor Spt20 PF12090.8 CDJ52481.1 - 0.022 14.4 36.4 0.026 14.2 25.2 3.0 3 0 0 3 3 3 0 Spt20 family DUF2052 PF09747.9 CDJ52481.1 - 0.022 14.9 10.7 0.036 14.2 6.9 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CRT10 PF08728.10 CDJ52481.1 - 0.08 11.1 4.6 0.11 10.6 4.6 1.2 1 0 0 1 1 1 0 CRT10 Endostatin PF06482.11 CDJ52481.1 - 0.22 11.0 13.9 0.069 12.6 8.0 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Coilin_N PF15862.5 CDJ52481.1 - 0.24 11.2 14.3 0.23 11.3 7.9 2.6 2 0 0 2 2 2 0 Coilin N-terminus cwf18 PF08315.12 CDJ52481.1 - 0.31 11.7 22.6 0.3 11.8 13.2 2.7 3 0 0 3 3 3 0 cwf18 pre-mRNA splicing factor DUF1980 PF09323.10 CDJ52481.1 - 0.38 10.7 4.4 0.2 11.6 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) FAM60A PF15396.6 CDJ52481.1 - 0.45 10.5 10.7 0.39 10.7 5.0 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Pex14_N PF04695.13 CDJ52481.1 - 0.71 10.5 30.7 0.084 13.5 12.9 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EPL1 PF10513.9 CDJ52481.1 - 0.82 10.0 18.1 0.14 12.6 6.9 2.5 3 0 0 3 3 2 0 Enhancer of polycomb-like DDRGK PF09756.9 CDJ52481.1 - 1.1 8.9 18.3 0.15 11.7 14.1 1.7 2 0 0 2 2 2 0 DDRGK domain CSG2 PF16965.5 CDJ52481.1 - 1.1 8.1 8.8 0.88 8.5 4.6 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator CPSF100_C PF13299.6 CDJ52481.1 - 1.3 9.2 20.2 0.37 11.0 9.2 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Cellulose_synt PF03552.14 CDJ52481.1 - 1.5 7.2 6.0 2.3 6.6 6.0 1.2 1 0 0 1 1 1 0 Cellulose synthase SpoIIP PF07454.11 CDJ52481.1 - 1.7 8.0 13.4 0.25 10.8 8.4 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Band_3_cyto PF07565.13 CDJ52481.1 - 2.7 7.7 15.0 1.3 8.7 9.0 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.12 CDJ52481.1 - 3.9 6.4 16.2 1.2 8.0 13.1 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 CDJ52481.1 - 5.3 6.8 20.1 3.3 7.5 13.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4614 PF15391.6 CDJ52481.1 - 5.5 6.9 29.8 1.7 8.6 6.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) XRN_M PF17846.1 CDJ52481.1 - 8.4 5.2 14.2 0.19 10.6 5.4 2.0 2 0 0 2 2 2 0 Xrn1 helical domain PA26 PF04636.13 CDJ52481.1 - 8.5 5.2 11.8 2.3 7.0 7.2 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) BatA PF07584.11 CDJ52482.1 - 2.4 8.6 4.6 23 5.4 0.5 3.8 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Spt20 PF12090.8 CDJ52483.1 - 0.7 9.5 7.6 0.69 9.5 7.6 1.1 1 0 0 1 1 1 0 Spt20 family Dehydrin PF00257.19 CDJ52483.1 - 2.8 8.5 10.8 3.4 8.2 10.8 1.2 1 0 0 1 1 1 0 Dehydrin TFIIA PF03153.13 CDJ52483.1 - 4.5 7.2 12.8 4.5 7.2 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 CDJ52483.1 - 5 6.2 23.4 6.3 5.9 23.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NAP PF00956.18 CDJ52485.1 - 2.4e-35 122.0 9.1 2.1e-19 69.8 0.0 4.4 3 2 1 4 4 4 3 Nucleosome assembly protein (NAP) YL1 PF05764.13 CDJ52485.1 - 0.00045 20.4 3.4 0.00085 19.5 3.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein Jun PF03957.13 CDJ52485.1 - 0.0064 16.4 6.4 0.0064 16.4 6.4 2.3 2 0 0 2 2 2 1 Jun-like transcription factor BTV_NS2 PF04514.12 CDJ52485.1 - 0.11 11.3 1.6 0.16 10.7 1.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Dehydrin PF00257.19 CDJ52485.1 - 5.6 7.5 20.6 5.2 7.6 3.9 2.5 2 0 0 2 2 2 0 Dehydrin HTH_9 PF08221.11 CDJ52486.1 - 0.043 13.9 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF2722 PF10846.8 CDJ52488.1 - 0.042 12.8 6.2 0.037 13.0 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Dopey_N PF04118.14 CDJ52488.1 - 0.068 12.3 0.5 0.072 12.2 0.5 1.0 1 0 0 1 1 1 0 Dopey, N-terminal Spt20 PF12090.8 CDJ52488.1 - 0.084 12.5 11.1 0.079 12.6 11.1 1.1 1 0 0 1 1 1 0 Spt20 family Peptidase_S8 PF00082.22 CDJ52489.1 - 4e-15 55.9 0.2 2.9e-08 33.3 0.1 2.1 2 0 0 2 2 2 2 Subtilase family DUF4614 PF15391.6 CDJ52492.1 - 0.002 18.1 13.0 0.002 18.1 13.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4614) NAM-associated PF14303.6 CDJ52492.1 - 0.0079 16.9 10.5 0.0079 16.9 10.5 2.2 2 1 0 2 2 2 1 No apical meristem-associated C-terminal domain Velvet PF11754.8 CDJ52492.1 - 0.058 13.3 5.4 0.091 12.7 1.3 2.1 2 0 0 2 2 2 0 Velvet factor Vitellogenin_N PF01347.22 CDJ52492.1 - 0.085 11.2 1.0 0.12 10.7 1.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region DUF572 PF04502.13 CDJ52492.1 - 0.62 9.6 8.8 0.26 10.9 4.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) MID_MedPIWI PF18296.1 CDJ52492.1 - 1 9.1 11.1 0.37 10.6 5.9 2.0 2 0 0 2 2 2 0 MID domain of medPIWI SPX PF03105.19 CDJ52492.1 - 1 9.2 15.6 1.9 8.3 15.6 1.4 1 1 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ52492.1 - 1.4 7.7 12.2 0.19 10.5 8.5 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain AUX_IAA PF02309.16 CDJ52492.1 - 1.4 8.7 6.2 0.4 10.5 0.9 2.0 2 0 0 2 2 2 0 AUX/IAA family FGF-BP1 PF06473.12 CDJ52492.1 - 1.7 8.5 8.8 1.4 8.7 3.4 2.2 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Raftlin PF15250.6 CDJ52492.1 - 2.2 6.9 6.4 0.69 8.6 3.1 1.7 2 0 0 2 2 2 0 Raftlin PI3K_1B_p101 PF10486.9 CDJ52492.1 - 2.6 5.7 9.8 3.7 5.2 9.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 CDJ52492.1 - 3 6.3 15.0 0.12 10.9 8.2 1.9 2 0 0 2 2 2 0 Macoilin family HABP4_PAI-RBP1 PF04774.15 CDJ52492.1 - 5 8.0 18.4 0.067 14.0 7.0 2.6 3 0 0 3 3 3 0 Hyaluronan / mRNA binding family Period_C PF12114.8 CDJ52492.1 - 5.3 6.6 24.6 11 5.5 24.6 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SOBP PF15279.6 CDJ52492.1 - 7.6 7.0 7.6 5.2 7.6 1.8 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein Presenilin PF01080.17 CDJ52492.1 - 8.1 5.1 11.7 1.7 7.3 6.4 1.9 2 0 0 2 2 2 0 Presenilin SRP-alpha_N PF04086.13 CDJ52492.1 - 8.1 6.3 19.7 0.61 10.0 10.2 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF515 PF04415.12 CDJ52492.1 - 9 4.6 16.4 13 4.0 16.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Cpn60_TCP1 PF00118.24 CDJ52495.1 - 2.8e-45 154.9 2.0 9.1e-31 107.0 0.9 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family BAF1_ABF1 PF04684.13 CDJ52496.1 - 0.0022 17.2 4.7 0.0022 17.2 4.7 6.2 5 2 1 6 6 6 2 BAF1 / ABF1 chromatin reorganising factor RskA PF10099.9 CDJ52496.1 - 0.0068 16.7 12.1 0.0068 16.7 12.1 12.4 5 4 4 9 9 9 2 Anti-sigma-K factor rskA Caldesmon PF02029.15 CDJ52497.1 - 0.0049 15.7 47.8 0.0071 15.2 47.8 1.2 1 0 0 1 1 1 1 Caldesmon MASE4 PF17158.4 CDJ52497.1 - 0.37 10.0 1.4 3.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Membrane-associated sensor, integral membrane domain CorA PF01544.18 CDJ52499.1 - 3.2e-08 33.3 0.0 5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ephrin_rec_like PF07699.13 CDJ52501.1 - 4.8e-07 29.4 26.6 0.0071 16.1 5.9 4.5 3 1 1 4 4 4 4 Putative ephrin-receptor like RANK_CRD_2 PF18278.1 CDJ52501.1 - 0.00074 19.6 2.3 0.001 19.2 0.4 2.2 2 0 0 2 2 2 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 DUF2722 PF10846.8 CDJ52503.1 - 0.00044 19.3 8.8 0.00059 18.9 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DDHD PF02862.17 CDJ52503.1 - 0.0026 18.0 0.0 0.026 14.7 0.0 2.1 2 0 0 2 2 2 1 DDHD domain Med15 PF09606.10 CDJ52503.1 - 0.0073 15.1 11.2 0.01 14.6 11.2 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ52503.1 - 0.0091 16.0 11.7 0.014 15.5 11.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ52503.1 - 0.0098 15.5 18.6 0.019 14.6 18.6 1.4 1 0 0 1 1 1 1 Spt20 family DUF4820 PF16091.5 CDJ52503.1 - 0.09 12.1 2.7 0.15 11.4 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3506 PF12014.8 CDJ52503.1 - 0.2 11.7 0.9 0.34 10.9 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Suf PF05843.14 CDJ52503.1 - 0.21 11.6 4.4 0.31 11.0 4.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Roughex PF06020.11 CDJ52503.1 - 0.31 10.1 9.2 0.46 9.5 9.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF1180 PF06679.12 CDJ52503.1 - 0.32 11.4 0.7 4.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF4407 PF14362.6 CDJ52503.1 - 0.37 10.1 5.7 0.82 9.0 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4834 PF16118.5 CDJ52503.1 - 0.67 10.9 8.7 0.31 12.0 5.7 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) EIIBC-GUT_N PF03612.14 CDJ52503.1 - 0.79 9.4 3.6 1.7 8.4 3.6 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4175 PF13779.6 CDJ52503.1 - 1.3 6.8 14.5 1.9 6.3 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FAM176 PF14851.6 CDJ52503.1 - 1.6 8.4 4.6 0.67 9.6 1.6 1.8 2 0 0 2 2 2 0 FAM176 family eIF-3_zeta PF05091.12 CDJ52503.1 - 3 6.7 7.9 3.1 6.7 6.2 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ52503.1 - 3.7 7.6 9.5 6.9 6.7 9.5 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 dsDNA_bind PF01984.20 CDJ52503.1 - 4 7.8 23.2 9.4 6.6 22.3 1.9 2 0 0 2 2 2 0 Double-stranded DNA-binding domain WRNPLPNID PF15017.6 CDJ52503.1 - 7 7.6 10.4 19 6.2 10.4 1.7 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box MMR1 PF08505.10 CDJ52503.1 - 7.6 6.7 10.1 13 6.0 10.1 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PBP_sp32 PF07222.12 CDJ52503.1 - 8.4 5.8 12.3 16 4.8 12.3 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ribosomal_S7 PF00177.21 CDJ52506.1 - 2.2e-15 56.6 0.0 6.6e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e PAT1 PF09770.9 CDJ52507.1 - 0.01 14.2 45.9 0.011 14.1 45.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AF-4 PF05110.13 CDJ52507.1 - 0.022 12.9 49.6 0.028 12.5 49.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein HemX PF04375.14 CDJ52507.1 - 0.034 13.5 38.5 0.066 12.5 38.5 1.6 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Exonuc_VII_L PF02601.15 CDJ52507.1 - 0.16 11.5 24.5 0.19 11.3 24.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.8 CDJ52507.1 - 1.1 8.0 23.2 0.049 12.5 18.0 1.5 2 0 0 2 2 2 0 Aluminium activated malate transporter GREB1 PF15782.5 CDJ52507.1 - 1.6 5.8 32.4 1.8 5.6 32.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ten_N PF06484.12 CDJ52507.1 - 6.3 6.6 29.8 8.4 6.2 29.8 1.4 1 0 0 1 1 1 0 Teneurin Intracellular Region Med15 PF09606.10 CDJ52507.1 - 7.1 5.2 58.7 8.3 5.0 58.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Dicty_REP PF05086.12 CDJ52507.1 - 7.7 4.4 17.8 12 3.7 17.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF846 PF05832.12 CDJ52508.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DUF3040 PF11239.8 CDJ52508.1 - 0.64 10.3 9.5 4.6 7.6 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF1772 PF08592.11 CDJ52508.1 - 1.5 9.1 17.8 0.064 13.6 1.3 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) AurF PF11583.8 CDJ52509.1 - 1 8.6 10.8 0.87 8.8 9.6 1.5 1 1 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF SOBP PF15279.6 CDJ52509.1 - 1.7 9.2 11.2 1.9 9.0 11.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Med26_M PF15694.5 CDJ52509.1 - 2.7 8.0 13.8 2.4 8.1 11.9 1.7 1 1 1 2 2 2 0 Mediator complex subunit 26 middle domain RGS-like PF09128.11 CDJ52509.1 - 3.3 7.4 10.0 5 6.8 10.0 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain YABBY PF04690.13 CDJ52509.1 - 8.9 6.9 9.9 88 3.6 9.9 2.2 1 1 0 1 1 1 0 YABBY protein FAM176 PF14851.6 CDJ52510.1 - 0.007 16.0 2.9 0.007 16.0 2.9 5.1 2 2 3 5 5 5 1 FAM176 family Na_trans_assoc PF06512.13 CDJ52510.1 - 0.018 15.3 0.0 0.018 15.3 0.0 3.2 2 1 1 3 3 3 0 Sodium ion transport-associated Orf78 PF06024.12 CDJ52510.1 - 0.019 15.3 0.8 0.019 15.3 0.8 5.0 5 0 0 5 5 5 0 Orf78 (ac78) MASE4 PF17158.4 CDJ52510.1 - 0.27 10.5 0.2 0.52 9.5 0.2 1.4 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain RskA PF10099.9 CDJ52510.1 - 0.44 10.8 59.1 0.03 14.6 19.4 4.0 2 2 1 3 3 3 0 Anti-sigma-K factor rskA LANC_like PF05147.13 CDJ52511.1 - 9.9e-11 40.8 8.8 0.00055 18.6 0.0 4.7 5 0 0 5 5 5 3 Lanthionine synthetase C-like protein SPX PF03105.19 CDJ52511.1 - 0.0031 17.5 1.3 0.0031 17.5 1.3 3.3 2 1 0 2 2 2 1 SPX domain SUIM_assoc PF16619.5 CDJ52511.1 - 0.035 14.2 0.3 0.035 14.2 0.3 10.6 4 3 2 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 Macoilin PF09726.9 CDJ52512.1 - 0.0009 17.9 49.7 0.0009 17.9 49.7 4.7 4 2 1 5 5 5 1 Macoilin family DAPG_hydrolase PF18089.1 CDJ52512.1 - 0.11 12.0 5.1 0.026 14.1 0.7 2.2 2 0 0 2 2 2 0 DAPG hydrolase PhiG domain HC2 PF07382.11 CDJ52513.1 - 0.47 10.5 8.4 0.7 9.9 8.4 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 LMBR1 PF04791.16 CDJ52514.1 - 3.7e-05 22.8 4.5 3.7e-05 22.8 4.5 2.1 2 0 0 2 2 2 1 LMBR1-like membrane protein PIG-U PF06728.13 CDJ52514.1 - 0.00049 19.3 9.7 0.0015 17.6 9.7 1.8 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U TFIIA PF03153.13 CDJ52514.1 - 0.00054 20.1 27.7 0.00054 20.1 27.7 2.5 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit EMC3_TMCO1 PF01956.16 CDJ52514.1 - 0.0082 15.9 1.4 0.0082 15.9 1.4 2.9 3 1 0 3 3 3 1 Integral membrane protein EMC3/TMCO1-like CPSF100_C PF13299.6 CDJ52514.1 - 0.072 13.3 22.7 0.019 15.1 5.3 3.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal CNDH2_C PF16858.5 CDJ52514.1 - 0.38 10.6 24.0 1.1 9.1 11.0 2.5 2 1 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4175 PF13779.6 CDJ52514.1 - 0.42 8.5 55.5 0.024 12.6 15.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) PIG-S PF10510.9 CDJ52514.1 - 1.3 7.8 30.3 0.04 12.7 14.5 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein Smg8_Smg9 PF10220.9 CDJ52514.1 - 2.1 6.5 25.8 0.3 9.4 10.4 2.3 2 0 0 2 2 2 0 Smg8_Smg9 PAT1 PF09770.9 CDJ52514.1 - 2.4 6.3 50.0 0.16 10.2 15.9 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TT_ORF1 PF02956.14 CDJ52514.1 - 2.8 6.5 25.0 0.61 8.7 3.3 2.2 2 0 0 2 2 2 0 TT viral orf 1 GREB1 PF15782.5 CDJ52514.1 - 4.2 4.3 39.7 0.082 10.0 19.9 2.2 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer SpoIIP PF07454.11 CDJ52514.1 - 4.2 6.7 31.8 0.057 12.9 10.5 2.8 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) Exonuc_VII_L PF02601.15 CDJ52514.1 - 7.4 6.1 30.3 4.5 6.8 9.2 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Rtf2 PF04641.12 CDJ52514.1 - 7.8 5.8 31.8 0.23 10.8 5.5 3.2 3 0 0 3 3 3 0 Rtf2 RING-finger Afi1 PF07792.12 CDJ52514.1 - 7.9 7.0 31.8 1.1 9.8 12.6 3.3 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3807 PF12720.7 CDJ52514.1 - 9.7 6.4 44.7 2.9 8.2 14.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) DUF755 PF05501.11 CDJ52515.1 - 0.0039 17.5 19.2 0.0039 17.5 19.2 5.2 5 1 0 5 5 5 1 Domain of unknown function (DUF755) DUF1645 PF07816.11 CDJ52515.1 - 0.011 16.3 12.3 0.011 16.3 12.3 4.5 4 2 0 4 4 4 0 Protein of unknown function (DUF1645) EF-hand_1 PF00036.32 CDJ52516.1 - 4.8e-23 78.9 0.1 1.5e-06 27.3 0.0 4.3 4 0 0 4 4 4 3 EF hand Pkinase PF00069.25 CDJ52516.1 - 7.5e-23 81.2 5.0 4.6e-13 49.2 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain EF-hand_5 PF13202.6 CDJ52516.1 - 7.1e-18 63.2 0.3 1.4e-06 27.5 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ52516.1 - 8.5e-18 64.6 0.0 1.2e-09 38.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ52516.1 - 5.5e-17 60.2 0.0 3e-06 26.7 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CDJ52516.1 - 7.9e-14 51.3 2.6 0.00039 20.2 0.1 4.6 2 1 2 4 4 4 2 EF-hand domain pair Pkinase_Tyr PF07714.17 CDJ52516.1 - 4.1e-08 32.8 4.4 0.00057 19.3 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase TFIIA PF03153.13 CDJ52516.1 - 0.01 15.9 22.0 0.01 15.9 22.0 2.3 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 CDJ52516.1 - 0.024 15.2 14.1 0.17 12.4 7.6 2.3 2 0 0 2 2 2 0 AAA domain TMEM214 PF10151.9 CDJ52516.1 - 0.041 12.3 10.9 0.07 11.6 10.9 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator EOS1 PF12326.8 CDJ52516.1 - 0.28 11.1 3.4 0.5 10.3 0.4 2.1 2 0 0 2 2 2 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ52516.1 - 1.1 8.1 15.3 0.052 12.5 8.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 CDJ52516.1 - 1.9 8.6 12.3 4.9 7.3 12.3 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal UBA_e1_thiolCys PF10585.9 CDJ52516.1 - 3.6 7.4 13.8 16 5.3 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-activating enzyme active site DDHD PF02862.17 CDJ52516.1 - 3.7 7.7 13.7 0.032 14.4 3.1 2.4 2 1 0 2 2 2 0 DDHD domain NARP1 PF12569.8 CDJ52516.1 - 5.7 5.7 14.0 62 2.3 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RT_RNaseH PF17917.1 CDJ52517.1 - 1.2e-16 60.9 0.7 2e-16 60.2 0.7 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 CDJ52517.1 - 8e-11 41.7 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CDJ52517.1 - 2.3e-07 31.0 0.2 1.1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 CDJ52517.1 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ52517.1 - 0.016 15.1 0.1 0.038 13.8 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase-like PWI PF01480.17 CDJ52518.1 - 0.001 19.3 5.1 0.002 18.4 5.1 1.7 1 1 0 1 1 1 1 PWI domain DUF3381 PF11861.8 CDJ52518.1 - 0.042 13.6 21.9 0.045 13.6 21.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RXT2_N PF08595.11 CDJ52518.1 - 0.066 13.2 13.3 0.079 13.0 13.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PAT1 PF09770.9 CDJ52518.1 - 0.13 10.5 31.1 0.14 10.4 31.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.17 CDJ52518.1 - 0.15 12.2 16.0 0.15 12.2 16.0 1.1 1 0 0 1 1 1 0 DDHD domain Baculo_PP31 PF05311.11 CDJ52518.1 - 0.17 11.3 16.1 0.17 11.3 16.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF4228 PF14009.6 CDJ52518.1 - 0.22 11.9 8.3 0.22 11.9 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) PIP5K PF01504.18 CDJ52518.1 - 0.23 10.6 14.0 0.22 10.7 14.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase MDM31_MDM32 PF08118.11 CDJ52518.1 - 0.25 9.9 10.4 0.26 9.9 10.4 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Pex14_N PF04695.13 CDJ52518.1 - 0.32 11.6 31.7 0.35 11.5 31.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 CDJ52518.1 - 0.65 9.8 21.2 0.69 9.7 21.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CSG2 PF16965.5 CDJ52518.1 - 0.69 8.8 10.0 0.67 8.8 10.0 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator CPSF100_C PF13299.6 CDJ52518.1 - 0.97 9.6 16.5 1 9.5 16.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SID-1_RNA_chan PF13965.6 CDJ52518.1 - 1 7.7 8.9 0.93 7.8 8.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 CDJ52518.1 - 1.3 7.7 24.5 1.3 7.7 24.5 1.0 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ52518.1 - 1.4 7.8 27.3 1.4 7.8 27.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ctr PF04145.15 CDJ52518.1 - 1.4 9.5 10.1 1.4 9.5 10.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF913 PF06025.12 CDJ52518.1 - 1.5 7.7 15.7 1.6 7.6 15.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFIIA PF03153.13 CDJ52518.1 - 1.5 8.7 49.2 1.7 8.6 49.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 CDJ52518.1 - 1.8 8.5 15.1 1.8 8.5 15.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 CDJ52518.1 - 1.8 7.5 19.6 1.9 7.4 19.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CobT PF06213.12 CDJ52518.1 - 1.9 7.8 31.6 2.2 7.6 31.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Band_3_cyto PF07565.13 CDJ52518.1 - 2 8.2 19.5 2.2 8.0 19.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CCDC53 PF10152.9 CDJ52518.1 - 2.1 8.7 23.1 2.4 8.6 23.1 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex EOS1 PF12326.8 CDJ52518.1 - 2.2 8.2 10.9 2.3 8.1 10.9 1.2 1 0 0 1 1 1 0 N-glycosylation protein Folate_carrier PF01770.18 CDJ52518.1 - 2.6 6.7 9.4 2.5 6.7 9.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier Phage_GPO PF05929.11 CDJ52518.1 - 2.7 7.5 21.7 2.6 7.6 21.7 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SpoIIP PF07454.11 CDJ52518.1 - 2.8 7.3 25.7 3.1 7.2 25.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) HCO3_cotransp PF00955.21 CDJ52518.1 - 2.9 6.6 8.1 2.7 6.7 8.1 1.0 1 0 0 1 1 1 0 HCO3- transporter family Paf1 PF03985.13 CDJ52518.1 - 2.9 6.8 25.8 3.1 6.7 25.8 1.0 1 0 0 1 1 1 0 Paf1 CBP_BcsG PF11658.8 CDJ52518.1 - 3.1 6.1 16.1 3.1 6.1 16.1 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Peptidase_U57 PF05582.12 CDJ52518.1 - 3.3 6.9 15.3 3.5 6.8 15.3 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Pannexin_like PF12534.8 CDJ52518.1 - 4.3 6.3 15.9 4.7 6.2 15.9 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF3408 PF11888.8 CDJ52518.1 - 4.7 7.3 22.2 5.9 7.0 22.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF4746 PF15928.5 CDJ52518.1 - 5.3 6.4 17.7 5.8 6.2 17.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ALMT PF11744.8 CDJ52518.1 - 5.4 5.7 17.0 5.6 5.7 17.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Tim54 PF11711.8 CDJ52518.1 - 8.4 5.1 20.3 8.9 5.0 20.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 CDJ52518.1 - 9 6.3 21.2 11 6.0 21.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Otopetrin PF03189.13 CDJ52518.1 - 9.2 5.0 14.0 9.9 4.8 14.0 1.0 1 0 0 1 1 1 0 Otopetrin PPL5 PF18168.1 CDJ52518.1 - 9.4 5.4 16.0 9.6 5.4 16.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 VPS9 PF02204.18 CDJ52520.1 - 2.2e-26 92.1 0.0 4.8e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF2722 PF10846.8 CDJ52520.1 - 0.00048 19.2 1.4 0.00048 19.2 1.4 8.0 5 2 1 7 7 7 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ52523.1 - 0.00064 19.8 7.2 0.00069 19.7 7.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ52523.1 - 0.001 18.1 9.2 0.0013 17.7 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ52523.1 - 0.063 13.3 1.2 0.07 13.1 1.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med3 PF11593.8 CDJ52523.1 - 3.1 6.9 17.8 4.8 6.3 17.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Androgen_recep PF02166.16 CDJ52523.1 - 4 6.2 21.8 0.2 10.5 16.3 1.7 2 0 0 2 2 2 0 Androgen receptor ParA PF10609.9 CDJ52524.1 - 5.6e-25 88.2 0.7 8.4e-25 87.6 0.0 1.7 2 0 0 2 2 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CDJ52524.1 - 2.1e-08 34.2 0.0 4.5e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CDJ52524.1 - 8.4e-06 25.2 2.4 4.8e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 CDJ52524.1 - 3.8e-05 23.1 0.0 0.00037 19.9 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 CDJ52524.1 - 7.6e-05 22.7 1.4 9.3e-05 22.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF2681 PF10883.8 CDJ52524.1 - 0.0006 20.2 24.4 0.02 15.3 13.9 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2681) RsgA_GTPase PF03193.16 CDJ52524.1 - 0.0015 18.4 1.9 0.0016 18.3 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase EphA2_TM PF14575.6 CDJ52524.1 - 0.0018 19.1 0.9 0.016 16.0 0.2 2.1 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Presenilin PF01080.17 CDJ52524.1 - 0.0023 16.7 2.8 0.0028 16.5 2.8 1.1 1 0 0 1 1 1 1 Presenilin NB-ARC PF00931.22 CDJ52524.1 - 0.0024 17.1 0.1 0.0024 17.1 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 CDJ52524.1 - 0.0028 17.3 0.4 0.0059 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain LapA_dom PF06305.11 CDJ52524.1 - 0.0032 17.2 2.3 0.0032 17.2 2.3 2.1 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain PH_4 PF15404.6 CDJ52524.1 - 0.0082 16.0 1.0 0.73 9.6 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain CBP_BcsQ PF06564.12 CDJ52524.1 - 0.011 15.3 0.1 0.011 15.3 0.1 2.8 2 1 1 3 3 3 0 Cellulose biosynthesis protein BcsQ DUF3824 PF12868.7 CDJ52524.1 - 0.013 16.1 0.3 0.013 16.1 0.3 2.9 2 1 0 2 2 1 0 Domain of unknwon function (DUF3824) DUF533 PF04391.12 CDJ52524.1 - 0.014 15.0 25.3 0.13 11.8 8.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF533) AAA_18 PF13238.6 CDJ52524.1 - 0.015 15.9 0.7 0.053 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain PmbA_TldD PF01523.16 CDJ52524.1 - 0.017 15.0 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase MeaB PF03308.16 CDJ52524.1 - 0.018 14.0 0.3 0.018 14.0 0.3 2.4 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 CDJ52524.1 - 0.025 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 CDJ52524.1 - 0.026 14.8 0.7 0.61 10.4 0.2 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CDJ52524.1 - 0.028 13.5 0.0 0.028 13.5 0.0 1.5 2 0 0 2 2 1 0 Type II/IV secretion system protein DUF4820 PF16091.5 CDJ52524.1 - 0.028 13.8 5.9 0.068 12.5 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) IstB_IS21 PF01695.17 CDJ52524.1 - 0.032 14.0 0.1 0.032 14.0 0.1 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 CDJ52524.1 - 0.034 14.5 0.1 0.034 14.5 0.1 2.5 1 1 1 2 2 1 0 AAA ATPase domain Rad17 PF03215.15 CDJ52524.1 - 0.05 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain DUF4834 PF16118.5 CDJ52524.1 - 0.053 14.5 8.5 0.2 12.7 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4179 PF13786.6 CDJ52524.1 - 0.055 13.9 6.6 1.1 9.7 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) TsaE PF02367.17 CDJ52524.1 - 0.056 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 CDJ52524.1 - 0.057 13.3 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 NTPase DUF2722 PF10846.8 CDJ52524.1 - 0.064 12.2 22.2 0.41 9.5 16.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Ndc1_Nup PF09531.10 CDJ52524.1 - 0.096 11.4 4.7 0.12 11.0 4.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PIF1 PF05970.14 CDJ52524.1 - 0.1 11.7 3.0 0.69 9.0 0.2 2.1 2 0 0 2 2 2 0 PIF1-like helicase DUF2828 PF11443.8 CDJ52524.1 - 0.13 10.4 3.1 0.16 10.0 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CLN3 PF02487.17 CDJ52524.1 - 0.13 11.3 0.7 0.19 10.8 0.7 1.2 1 0 0 1 1 1 0 CLN3 protein PIP5K PF01504.18 CDJ52524.1 - 0.13 11.4 1.7 0.18 11.0 1.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Trp_oprn_chp PF09534.10 CDJ52524.1 - 0.15 11.9 25.0 0.068 13.0 7.8 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2371 PF10177.9 CDJ52524.1 - 0.15 12.2 1.7 2 8.6 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Sporozoite_P67 PF05642.11 CDJ52524.1 - 0.17 10.0 6.4 0.21 9.7 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ResIII PF04851.15 CDJ52524.1 - 0.18 11.8 4.4 0.51 10.3 0.4 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit FAM176 PF14851.6 CDJ52524.1 - 0.19 11.4 1.8 0.29 10.8 0.3 1.9 2 0 0 2 2 2 0 FAM176 family MDM10 PF12519.8 CDJ52524.1 - 0.19 10.6 1.0 0.27 10.1 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Methyltransf_34 PF11312.8 CDJ52524.1 - 0.2 10.9 6.8 0.28 10.4 6.8 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Shadoo PF14999.6 CDJ52524.1 - 0.21 11.7 20.8 5.3 7.1 0.1 2.7 2 1 0 2 2 2 0 Shadow of prion protein, neuroprotective KTI12 PF08433.10 CDJ52524.1 - 0.27 10.7 0.0 0.27 10.7 0.0 2.3 2 1 0 2 2 2 0 Chromatin associated protein KTI12 DUF3371 PF11851.8 CDJ52524.1 - 0.3 12.2 7.8 1.2 10.3 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) DUF3450 PF11932.8 CDJ52524.1 - 0.34 10.2 27.0 0.54 9.5 6.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SpoIIP PF07454.11 CDJ52524.1 - 0.46 9.9 5.9 3.5 7.0 2.4 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) MPM1 PF17234.2 CDJ52524.1 - 0.54 10.5 11.1 0.25 11.6 5.4 2.0 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 FxsA PF04186.13 CDJ52524.1 - 0.56 10.4 3.6 1 9.5 0.3 2.3 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein AAA_24 PF13479.6 CDJ52524.1 - 0.81 9.4 0.1 0.81 9.4 0.1 2.3 3 0 0 3 3 2 0 AAA domain DUF5362 PF17319.2 CDJ52524.1 - 0.93 9.4 3.4 0.51 10.2 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5362) G-alpha PF00503.20 CDJ52524.1 - 1.1 8.4 4.4 0.28 10.3 0.7 1.7 2 0 0 2 2 2 0 G-protein alpha subunit SLATT_1 PF18181.1 CDJ52524.1 - 1.2 9.1 13.3 2.2 8.3 1.5 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Conotoxin PF02950.17 CDJ52524.1 - 1.2 10.2 8.8 2.3 9.3 3.2 2.4 2 0 0 2 2 2 0 Conotoxin RAB3GAP2_N PF14655.6 CDJ52524.1 - 1.5 8.0 11.8 2 7.6 5.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Gaa1 PF04114.14 CDJ52524.1 - 1.7 7.6 4.2 2.5 7.0 4.2 1.5 1 1 0 1 1 1 0 Gaa1-like, GPI transamidase component Herpes_DNAp_acc PF04929.12 CDJ52524.1 - 1.7 7.5 5.3 2.3 7.1 5.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Senescence_reg PF04520.13 CDJ52524.1 - 1.9 9.3 7.7 2.7 8.8 7.7 1.2 1 0 0 1 1 1 0 Senescence regulator DUF5349 PF17298.2 CDJ52524.1 - 2.1 8.0 11.4 11 5.7 8.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5349) OPA3 PF07047.12 CDJ52524.1 - 2.4 8.0 10.5 3 7.6 1.8 2.2 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) ANAPC_CDC26 PF10471.9 CDJ52524.1 - 2.5 9.0 29.6 1.8 9.4 17.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 RNA_pol_Rpc4 PF05132.14 CDJ52524.1 - 2.6 8.5 13.1 7.4 7.0 1.6 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF2367 PF10164.9 CDJ52524.1 - 2.7 8.5 8.1 11 6.5 2.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) IHABP4_N PF16174.5 CDJ52524.1 - 3.7 8.1 19.1 4.8 7.8 3.8 2.1 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Suf PF05843.14 CDJ52524.1 - 3.8 7.4 14.6 6.3 6.7 7.4 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TMEM51 PF15345.6 CDJ52524.1 - 3.9 7.2 10.4 1.5 8.6 4.2 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 Band_3_cyto PF07565.13 CDJ52524.1 - 4.8 6.9 8.6 7.8 6.2 8.6 1.3 1 1 0 1 1 1 0 Band 3 cytoplasmic domain Coilin_N PF15862.5 CDJ52524.1 - 5.1 6.9 12.6 1.3 8.9 3.2 2.1 2 0 0 2 2 2 0 Coilin N-terminus DUF3138 PF11336.8 CDJ52524.1 - 5.4 5.5 20.7 7.6 5.0 20.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RskA PF10099.9 CDJ52524.1 - 5.7 7.2 41.7 0.56 10.5 13.1 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF2489 PF10675.9 CDJ52524.1 - 7.3 6.5 21.4 2.2 8.2 11.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) SWI-SNF_Ssr4 PF08549.10 CDJ52524.1 - 7.5 5.1 13.1 9.8 4.7 13.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF2719 PF10891.8 CDJ52525.1 - 0.14 12.0 0.1 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2719) DUF5305 PF17231.2 CDJ52525.1 - 0.2 11.1 0.1 0.41 10.0 0.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5305) DUF572 PF04502.13 CDJ52525.1 - 0.71 9.4 31.3 1.1 8.8 31.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3206 PF11472.8 CDJ52525.1 - 1.4 8.9 3.6 4.6 7.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3206) Ribosomal_60s PF00428.19 CDJ52526.1 - 0.0042 17.6 4.9 0.0042 17.6 4.9 5.5 3 2 1 4 4 4 1 60s Acidic ribosomal protein DUF4569 PF15133.6 CDJ52527.1 - 0.5 10.1 11.5 0.5 10.0 11.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Peptidase_S49_N PF08496.10 CDJ52527.1 - 0.64 10.1 9.2 0.68 10.0 9.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal R_equi_Vir PF05526.11 CDJ52527.1 - 0.69 9.7 11.0 0.76 9.6 11.0 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Presenilin PF01080.17 CDJ52527.1 - 0.96 8.1 13.7 1 8.1 13.7 1.0 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ52527.1 - 1.3 9.7 21.8 1.6 9.4 21.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gastrin PF00918.17 CDJ52527.1 - 1.4 9.9 11.0 2 9.4 11.0 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Lys-AminoMut_A PF09043.11 CDJ52527.1 - 1.5 7.2 9.7 1.6 7.1 9.7 1.0 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Ctr PF04145.15 CDJ52527.1 - 1.6 9.3 5.4 1.9 9.1 5.4 1.2 1 0 0 1 1 1 0 Ctr copper transporter family CPSF100_C PF13299.6 CDJ52527.1 - 1.6 8.8 9.1 2.1 8.5 9.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3450 PF11932.8 CDJ52527.1 - 2.1 7.6 27.6 2.6 7.3 27.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FAM199X PF15814.5 CDJ52527.1 - 2.8 6.9 11.8 3 6.8 11.8 1.0 1 0 0 1 1 1 0 Protein family FAM199X Connexin PF00029.19 CDJ52527.1 - 3.2 7.5 7.8 3.2 7.5 7.8 1.1 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 CDJ52527.1 - 3.3 6.5 6.2 3.4 6.5 6.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.13 CDJ52527.1 - 3.3 7.6 34.2 3.6 7.5 34.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.6 CDJ52527.1 - 3.3 7.6 19.2 3.6 7.5 19.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1980 PF09323.10 CDJ52527.1 - 3.6 7.5 6.0 3.9 7.4 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) BAF1_ABF1 PF04684.13 CDJ52527.1 - 5.7 5.9 16.4 6.5 5.7 16.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CLN3 PF02487.17 CDJ52527.1 - 9.8 5.1 7.1 11 5.0 7.1 1.2 1 0 0 1 1 1 0 CLN3 protein Roughex PF06020.11 CDJ52528.1 - 4.4 6.3 10.5 4.8 6.2 10.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Band_3_cyto PF07565.13 CDJ52528.1 - 7.1 6.4 15.5 7.7 6.2 15.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SelP_N PF04592.14 CDJ52528.1 - 7.6 5.9 13.1 8.7 5.7 13.1 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1180 PF06679.12 CDJ52529.1 - 2.8e-05 24.6 4.4 2.8e-05 24.6 4.4 5.0 1 1 3 4 4 4 1 Protein of unknown function (DUF1180) SR-25 PF10500.9 CDJ52529.1 - 0.0082 15.8 46.9 0.25 10.9 9.3 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein PAT1 PF09770.9 CDJ52529.1 - 8.6 4.5 43.1 14 3.8 43.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF5427 PF10310.9 CDJ52530.1 - 8.9 5.1 44.1 11 4.9 44.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SUIM_assoc PF16619.5 CDJ52531.1 - 0.013 15.5 2.2 0.013 15.5 2.2 3.2 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PAN_4 PF14295.6 CDJ52531.1 - 0.019 14.9 0.7 0.019 14.9 0.7 2.4 2 0 0 2 2 2 0 PAN domain SR-25 PF10500.9 CDJ52531.1 - 1.1 8.8 19.6 2.6 7.6 15.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 CDJ52531.1 - 3.3 8.4 13.7 8.4 7.0 7.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IMUP PF15761.5 CDJ52531.1 - 5.9 7.6 18.3 2.8 8.7 9.1 2.6 2 1 0 2 2 2 0 Immortalisation up-regulated protein RskA PF10099.9 CDJ52532.1 - 0.012 15.9 43.3 0.037 14.3 0.0 4.0 1 1 2 3 3 3 0 Anti-sigma-K factor rskA DUF1772 PF08592.11 CDJ52532.1 - 0.065 13.5 0.1 0.2 11.9 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF2339 PF10101.9 CDJ52532.1 - 0.15 10.6 0.1 0.19 10.3 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) O-antigen_lig PF13425.6 CDJ52532.1 - 0.24 10.1 6.3 0.4 9.4 6.3 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF819 PF05684.12 CDJ52532.1 - 0.38 9.7 2.0 0.44 9.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF819) DUF5531 PF17671.1 CDJ52532.1 - 0.62 9.9 6.2 1.4 8.8 6.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5531) FSAP_sig_propep PF03032.15 CDJ52532.1 - 0.64 10.1 0.1 0.64 10.1 0.1 3.0 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide CitMHS_2 PF16980.5 CDJ52532.1 - 7.6 5.1 6.2 0.73 8.4 0.7 1.8 2 0 0 2 2 2 0 Putative citrate transport SARAF PF06682.12 CDJ52532.1 - 7.6 6.1 34.5 0.64 9.6 23.2 2.1 1 1 2 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis SR-25 PF10500.9 CDJ52533.1 - 1.2e-05 25.0 48.4 1.2e-05 25.0 48.4 2.9 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Spore_GerAC PF05504.11 CDJ52533.1 - 6.2 7.0 15.6 0.042 14.1 6.6 1.8 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal DNA_methylase PF00145.17 CDJ52534.1 - 4.4e-12 46.0 4.3 1.9e-07 30.8 0.0 8.4 7 1 0 8 8 8 3 C-5 cytosine-specific DNA methylase PHD PF00628.29 CDJ52534.1 - 1.6e-08 34.3 4.4 1.6e-08 34.3 4.4 2.8 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 CDJ52534.1 - 8.2e-07 29.3 11.9 8.2e-07 29.3 11.9 3.5 3 0 0 3 3 3 1 Ring finger domain RskA PF10099.9 CDJ52534.1 - 5.9e-06 26.7 0.6 5.9e-06 26.7 0.6 18.2 6 5 3 12 12 12 1 Anti-sigma-K factor rskA zf-C3HC4_3 PF13920.6 CDJ52534.1 - 3.2e-05 23.7 8.6 3.2e-05 23.7 8.6 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ52534.1 - 0.00082 19.2 11.7 0.00082 19.2 11.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ52534.1 - 0.0071 16.2 11.5 0.0071 16.2 11.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 CDJ52534.1 - 0.17 11.8 7.6 0.019 14.9 2.4 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) FAM76 PF16046.5 CDJ52536.1 - 1 8.7 25.7 1.3 8.3 25.7 1.1 1 0 0 1 1 1 0 FAM76 protein Ribosomal_60s PF00428.19 CDJ52536.1 - 3.5 8.3 55.3 0.46 11.1 16.9 3.8 3 1 0 3 3 3 0 60s Acidic ribosomal protein Ferlin_C PF16165.5 CDJ52536.1 - 9.6 6.1 10.4 0.45 10.5 1.0 2.2 2 0 0 2 2 2 0 Ferlin C-terminus TFIIA PF03153.13 CDJ52537.1 - 0.0041 17.2 50.6 0.0049 16.9 50.6 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ52537.1 - 0.013 13.8 34.4 0.015 13.6 34.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pal1 PF08316.11 CDJ52537.1 - 0.18 12.6 8.8 9.4 7.0 8.8 2.2 1 1 0 1 1 1 0 Pal1 cell morphology protein GAGA_bind PF06217.12 CDJ52537.1 - 0.76 10.0 14.2 0.86 9.8 14.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family GREB1 PF15782.5 CDJ52537.1 - 0.79 6.8 15.3 0.86 6.6 15.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MRP-S31 PF15433.6 CDJ52537.1 - 1.3 8.7 19.8 1.5 8.4 19.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 CCSAP PF15748.5 CDJ52537.1 - 1.5 8.9 17.6 1.9 8.6 17.6 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Paramyxo_ncap PF00973.19 CDJ52537.1 - 2.4 7.0 9.6 2.7 6.8 9.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RR_TM4-6 PF06459.12 CDJ52537.1 - 3.3 7.5 14.4 3.9 7.2 14.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ52537.1 - 7.2 6.6 12.3 8.4 6.4 12.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SprA-related PF12118.8 CDJ52537.1 - 7.3 5.6 33.7 9.3 5.3 33.7 1.1 1 0 0 1 1 1 0 SprA-related family Arf PF00025.21 CDJ52538.1 - 3.2e-08 33.2 0.0 1.1e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family TFIIA PF03153.13 CDJ52538.1 - 0.00057 20.0 6.7 0.00067 19.8 6.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SRPRB PF09439.10 CDJ52538.1 - 0.015 14.8 0.3 0.038 13.4 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NARG2_C PF10505.9 CDJ52538.1 - 0.046 13.2 0.6 0.077 12.5 0.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus Roc PF08477.13 CDJ52538.1 - 0.13 12.5 0.0 0.97 9.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cwf_Cwc_15 PF04889.12 CDJ52538.1 - 0.14 11.9 4.9 0.39 10.4 4.9 1.7 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein G-alpha PF00503.20 CDJ52538.1 - 0.17 11.0 2.4 0.27 10.3 2.4 1.5 1 1 0 1 1 1 0 G-protein alpha subunit ESM4 PF15952.5 CDJ52538.1 - 0.87 10.0 12.8 2.1 8.7 12.9 1.7 1 1 0 1 1 1 0 Enhancer of split M4 family Macoilin PF09726.9 CDJ52538.1 - 6.7 5.1 19.8 0.06 11.9 7.2 2.1 2 0 0 2 2 2 0 Macoilin family OATP PF03137.20 CDJ52539.1 - 0.038 12.3 1.2 0.12 10.6 1.2 1.9 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2721 PF11026.8 CDJ52539.1 - 0.11 12.4 0.1 0.11 12.4 0.1 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF2721) Activator_LAG-3 PF11498.8 CDJ52539.1 - 4.9 6.0 67.2 2.7 6.9 50.0 2.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Otopetrin PF03189.13 CDJ52539.1 - 9.4 4.9 7.4 28 3.4 7.4 1.8 1 0 0 1 1 1 0 Otopetrin HC2 PF07382.11 CDJ52541.1 - 0.0066 16.5 3.1 0.0082 16.2 3.1 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 CPBP PF02517.16 CDJ52544.1 - 2.9e-06 27.5 24.4 0.2 12.0 20.5 5.1 2 1 0 2 2 2 2 CPBP intramembrane metalloprotease SPX PF03105.19 CDJ52544.1 - 0.36 10.7 39.0 0.012 15.6 8.8 3.2 3 0 0 3 3 3 0 SPX domain Pex14_N PF04695.13 CDJ52544.1 - 5.7 7.6 0.0 5.7 7.6 0.0 7.0 5 2 1 6 6 6 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YajC PF02699.15 CDJ52545.1 - 0.063 13.2 0.8 0.063 13.2 0.8 1.8 2 0 0 2 2 2 0 Preprotein translocase subunit Methyltransf_34 PF11312.8 CDJ52545.1 - 0.13 11.5 6.8 0.15 11.3 6.8 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase MccV PF17508.2 CDJ52545.1 - 1.5 9.4 9.6 1.9 9.1 9.6 1.1 1 0 0 1 1 1 0 Microcin V bacteriocin DUF5585 PF17823.1 CDJ52545.1 - 2.3 7.1 18.7 2.6 6.9 18.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5585) YebO PF13974.6 CDJ52546.1 - 0.3 11.2 2.7 1.3 9.1 0.0 3.1 4 0 0 4 4 4 0 YebO-like protein DUF3984 PF13136.6 CDJ52547.1 - 0.00058 19.4 21.4 0.00069 19.1 21.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Pet20 PF08692.10 CDJ52547.1 - 0.014 16.1 8.6 0.016 15.9 8.6 1.1 1 0 0 1 1 1 0 Mitochondrial protein Pet20 PTPRCAP PF15713.5 CDJ52547.1 - 0.15 12.3 20.9 0.22 11.8 20.9 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CPSF100_C PF13299.6 CDJ52547.1 - 0.2 11.8 16.9 0.24 11.6 16.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 CDJ52547.1 - 0.21 11.0 21.6 0.25 10.8 21.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Med19 PF10278.9 CDJ52547.1 - 0.29 11.1 18.1 0.32 10.9 18.1 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 ALMT PF11744.8 CDJ52547.1 - 0.35 9.6 17.8 0.35 9.6 17.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2052 PF09747.9 CDJ52547.1 - 0.37 10.9 20.8 0.39 10.8 20.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CCSAP PF15748.5 CDJ52547.1 - 0.45 10.6 27.9 0.47 10.6 27.9 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Endostatin PF06482.11 CDJ52547.1 - 0.47 9.9 23.7 0.52 9.7 23.7 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CLN3 PF02487.17 CDJ52547.1 - 0.5 9.3 16.1 0.51 9.3 16.1 1.0 1 0 0 1 1 1 0 CLN3 protein Peptidase_U57 PF05582.12 CDJ52547.1 - 0.51 9.5 13.2 0.58 9.4 13.2 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Pex14_N PF04695.13 CDJ52547.1 - 0.6 10.7 31.5 0.79 10.4 31.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PIP5K PF01504.18 CDJ52547.1 - 0.83 8.8 16.2 0.96 8.6 16.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase TFIIA PF03153.13 CDJ52547.1 - 0.86 9.5 48.1 1.2 9.0 48.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ52547.1 - 0.93 7.7 38.5 0.99 7.6 38.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ureide_permease PF07168.11 CDJ52547.1 - 1.1 7.9 8.8 1.3 7.7 8.8 1.2 1 0 0 1 1 1 0 Ureide permease RR_TM4-6 PF06459.12 CDJ52547.1 - 1.3 8.8 26.6 1.4 8.7 26.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2126 PF09899.9 CDJ52547.1 - 1.7 6.6 15.4 1.7 6.6 15.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) BORG_CEP PF14957.6 CDJ52547.1 - 2.2 9.5 18.5 2.7 9.2 18.5 1.2 1 0 0 1 1 1 0 Cdc42 effector SelP_N PF04592.14 CDJ52547.1 - 2.3 7.5 29.7 2.9 7.2 29.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region VIR_N PF15912.5 CDJ52547.1 - 2.5 7.6 13.5 3.2 7.3 13.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Pannexin_like PF12534.8 CDJ52547.1 - 2.7 7.0 20.0 3.3 6.7 20.0 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Band_3_cyto PF07565.13 CDJ52547.1 - 2.8 7.6 23.4 3.2 7.5 23.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Scs3p PF10261.9 CDJ52547.1 - 3.3 7.1 6.9 4.1 6.9 6.9 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF913 PF06025.12 CDJ52547.1 - 3.3 6.6 15.3 3.6 6.5 15.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM60A PF15396.6 CDJ52547.1 - 4.7 7.2 20.7 5.4 7.0 20.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 CDJ52547.1 - 5 5.8 31.6 5.4 5.7 31.6 1.0 1 0 0 1 1 1 0 Presenilin N6_N4_Mtase PF01555.18 CDJ52547.1 - 5 6.8 10.9 5.2 6.7 10.9 1.1 1 0 0 1 1 1 0 DNA methylase Rtf2 PF04641.12 CDJ52547.1 - 5 6.4 26.1 6.1 6.1 26.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Connexin PF00029.19 CDJ52547.1 - 5.2 6.8 20.5 6.6 6.4 20.5 1.3 1 0 0 1 1 1 0 Connexin Tim54 PF11711.8 CDJ52547.1 - 6.1 5.5 23.6 7.1 5.3 23.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hydin_ADK PF17213.3 CDJ52547.1 - 6.1 7.1 18.9 7.6 6.8 18.9 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Velvet PF11754.8 CDJ52547.1 - 6.2 6.7 22.4 6.7 6.6 22.4 1.1 1 0 0 1 1 1 0 Velvet factor Cellulose_synt PF03552.14 CDJ52547.1 - 6.6 5.1 10.5 6.9 5.0 10.5 1.0 1 0 0 1 1 1 0 Cellulose synthase Neur_chan_memb PF02932.16 CDJ52547.1 - 6.8 6.7 21.2 7.4 6.6 21.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MCM_bind PF09739.9 CDJ52547.1 - 6.9 5.0 24.8 8 4.8 24.8 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF2828 PF11443.8 CDJ52547.1 - 8 4.4 28.1 8.8 4.3 28.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Zip PF02535.22 CDJ52547.1 - 8.7 5.4 18.2 9.7 5.3 18.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.12 CDJ52547.1 - 9.6 5.0 30.4 11 4.8 30.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Trypan_PARP PF05887.11 CDJ52548.1 - 0.91 9.5 26.2 1.2 9.1 26.2 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 CDJ52548.1 - 4.2 6.9 30.5 5.9 6.4 29.6 1.7 1 1 1 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF5123 PF17161.4 CDJ52549.1 - 0.12 13.4 4.2 0.33 12.0 4.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5123) TFIIA PF03153.13 CDJ52550.1 - 0.023 14.7 32.4 0.026 14.5 32.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ52550.1 - 0.045 12.7 16.2 0.047 12.7 16.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SprA-related PF12118.8 CDJ52550.1 - 0.051 12.7 27.8 0.059 12.5 27.8 1.1 1 0 0 1 1 1 0 SprA-related family SelP_N PF04592.14 CDJ52550.1 - 0.065 12.6 23.6 0.099 12.0 23.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MAP70 PF07058.11 CDJ52550.1 - 0.16 10.7 15.1 0.17 10.6 15.1 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 SpoIIP PF07454.11 CDJ52550.1 - 0.24 10.8 12.8 0.27 10.7 12.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4407 PF14362.6 CDJ52550.1 - 0.26 10.6 11.5 0.28 10.5 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VESA1_N PF12785.7 CDJ52550.1 - 0.29 10.0 16.9 0.32 9.9 16.9 1.0 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 XRCC4 PF06632.12 CDJ52550.1 - 0.46 9.3 16.8 0.59 8.9 16.8 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Presenilin PF01080.17 CDJ52550.1 - 0.65 8.7 23.6 0.68 8.6 23.6 1.1 1 0 0 1 1 1 0 Presenilin Velvet PF11754.8 CDJ52550.1 - 0.73 9.7 21.0 0.9 9.4 21.0 1.2 1 0 0 1 1 1 0 Velvet factor FAM199X PF15814.5 CDJ52550.1 - 0.93 8.5 25.1 1.2 8.1 25.1 1.1 1 0 0 1 1 1 0 Protein family FAM199X PPP4R2 PF09184.11 CDJ52550.1 - 0.94 9.0 14.8 1 8.9 14.8 1.1 1 0 0 1 1 1 0 PPP4R2 Spore_coat_CotO PF14153.6 CDJ52550.1 - 0.98 9.3 19.6 1.1 9.1 19.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Suf PF05843.14 CDJ52550.1 - 1 9.3 21.6 1.4 8.8 21.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SOBP PF15279.6 CDJ52550.1 - 1.1 9.9 23.9 1.2 9.7 23.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF5427 PF10310.9 CDJ52550.1 - 1.4 7.7 21.9 2 7.3 21.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Zip PF02535.22 CDJ52550.1 - 1.9 7.7 15.3 2 7.6 15.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CCSAP PF15748.5 CDJ52550.1 - 1.9 8.6 34.3 2.4 8.3 34.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4175 PF13779.6 CDJ52550.1 - 2.1 6.1 29.8 2.4 5.9 29.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SWI-SNF_Ssr4 PF08549.10 CDJ52550.1 - 2.2 6.8 19.0 2.5 6.6 19.0 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PAT1 PF09770.9 CDJ52550.1 - 2.4 6.3 24.9 2.4 6.3 24.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NARP1 PF12569.8 CDJ52550.1 - 2.4 7.0 14.6 2.7 6.8 14.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Raftlin PF15250.6 CDJ52550.1 - 2.5 6.8 20.7 2.7 6.6 20.7 1.1 1 0 0 1 1 1 0 Raftlin CLN3 PF02487.17 CDJ52550.1 - 2.7 7.0 8.7 2.7 6.9 8.7 1.2 1 0 0 1 1 1 0 CLN3 protein DUF913 PF06025.12 CDJ52550.1 - 3.9 6.3 11.4 4.4 6.2 11.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Dsh_C PF12316.8 CDJ52550.1 - 4.1 7.8 27.2 4.8 7.5 27.2 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal HemX PF04375.14 CDJ52550.1 - 5.5 6.2 23.4 6.4 6.0 23.4 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase XRN_M PF17846.1 CDJ52550.1 - 5.6 5.8 10.8 5.7 5.8 10.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain LAP1C PF05609.12 CDJ52550.1 - 5.7 5.9 23.8 6.3 5.8 23.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PA26 PF04636.13 CDJ52550.1 - 5.9 5.7 14.5 6.4 5.6 14.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MCM_bind PF09739.9 CDJ52550.1 - 6.2 5.1 19.6 7.7 4.8 19.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Peptidase_S64 PF08192.11 CDJ52550.1 - 6.3 5.2 18.6 7.3 5.0 18.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF1980 PF09323.10 CDJ52550.1 - 6.3 6.7 11.1 8.3 6.3 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Membralin PF09746.9 CDJ52550.1 - 6.9 5.6 8.8 7.1 5.6 8.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein GREB1 PF15782.5 CDJ52550.1 - 7.7 3.5 27.4 8.5 3.3 27.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MAT1 PF06391.13 CDJ52550.1 - 8.6 6.1 24.2 5.8 6.7 22.9 1.3 1 1 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 RAP1 PF07218.11 CDJ52550.1 - 9.8 4.3 12.7 11 4.1 12.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AP3D1 PF06375.11 CDJ52552.1 - 0.025 14.8 6.5 0.032 14.5 6.5 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 TFIIA PF03153.13 CDJ52552.1 - 0.038 14.0 22.5 0.044 13.8 22.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC106 PF15794.5 CDJ52552.1 - 0.096 12.4 7.4 0.12 12.1 7.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TERB2 PF15101.6 CDJ52552.1 - 0.11 12.5 9.4 0.13 12.3 9.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ52552.1 - 0.12 12.0 24.6 0.15 11.7 24.6 1.1 1 0 0 1 1 1 0 Spt20 family SpoIIP PF07454.11 CDJ52552.1 - 0.19 11.2 5.7 0.2 11.1 5.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 CDJ52552.1 - 0.24 11.5 6.8 0.26 11.4 6.8 1.2 1 0 0 1 1 1 0 DDHD domain SLC12 PF03522.15 CDJ52552.1 - 0.24 10.4 4.7 0.25 10.3 4.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CNDH2_M PF16869.5 CDJ52552.1 - 0.25 12.0 6.7 0.31 11.7 6.7 1.2 1 0 0 1 1 1 0 PF16858 DUF4604 PF15377.6 CDJ52552.1 - 0.28 11.6 13.2 0.35 11.3 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) GREB1 PF15782.5 CDJ52552.1 - 0.29 8.2 8.0 0.31 8.1 8.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF755 PF05501.11 CDJ52552.1 - 0.44 10.8 19.8 0.58 10.4 19.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Connexin PF00029.19 CDJ52552.1 - 0.47 10.2 3.2 0.55 9.9 3.2 1.1 1 0 0 1 1 1 0 Connexin DUF913 PF06025.12 CDJ52552.1 - 0.68 8.9 3.8 0.7 8.8 3.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CDJ52552.1 - 1 8.0 11.4 1.1 7.9 11.4 1.1 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 CDJ52552.1 - 1.2 8.8 6.6 1.4 8.7 6.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SprA-related PF12118.8 CDJ52552.1 - 1.4 8.0 24.4 1.9 7.6 24.4 1.1 1 0 0 1 1 1 0 SprA-related family BAF1_ABF1 PF04684.13 CDJ52552.1 - 1.5 7.8 12.6 1.8 7.5 12.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor eIF-3_zeta PF05091.12 CDJ52552.1 - 1.6 7.6 11.6 1.8 7.5 11.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CDJ52552.1 - 1.6 9.7 11.1 2.3 9.2 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Roughex PF06020.11 CDJ52552.1 - 1.7 7.7 11.7 2 7.4 11.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Neur_chan_memb PF02932.16 CDJ52552.1 - 1.7 8.6 6.0 1.9 8.5 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MAJIN PF15077.6 CDJ52552.1 - 1.8 8.3 7.0 2.1 8.1 7.0 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF3408 PF11888.8 CDJ52552.1 - 1.8 8.7 8.2 2.9 8.0 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Hid1 PF12722.7 CDJ52552.1 - 1.8 6.6 7.1 1.8 6.6 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM176 PF14851.6 CDJ52552.1 - 2.1 8.0 5.3 2.6 7.7 5.3 1.2 1 0 0 1 1 1 0 FAM176 family DUF2681 PF10883.8 CDJ52552.1 - 2.5 8.6 14.9 4.7 7.7 14.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Paf1 PF03985.13 CDJ52552.1 - 2.8 6.9 13.2 3.6 6.5 13.2 1.1 1 0 0 1 1 1 0 Paf1 V_ATPase_I PF01496.19 CDJ52552.1 - 3 5.6 6.6 3.3 5.5 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPR3 PF03666.13 CDJ52552.1 - 3.1 6.5 10.0 3.5 6.3 10.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CLN3 PF02487.17 CDJ52552.1 - 3.3 6.7 4.3 3.7 6.5 4.3 1.1 1 0 0 1 1 1 0 CLN3 protein RR_TM4-6 PF06459.12 CDJ52552.1 - 3.5 7.4 9.0 4.1 7.2 9.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 CDJ52552.1 - 3.7 6.3 6.5 4 6.2 6.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Folliculin PF11704.8 CDJ52552.1 - 5.1 6.9 7.9 8.2 6.3 7.9 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport NEMP PF10225.9 CDJ52552.1 - 7 6.2 4.9 8.6 6.0 4.9 1.1 1 0 0 1 1 1 0 NEMP family API5 PF05918.11 CDJ52552.1 - 7.4 5.2 9.8 8.9 5.0 9.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MAT1 PF06391.13 CDJ52553.1 - 0.0037 17.1 27.5 0.005 16.7 27.5 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 SseC PF04888.12 CDJ52553.1 - 0.012 15.2 24.5 0.012 15.2 24.5 3.0 3 0 0 3 3 2 0 Secretion system effector C (SseC) like family PRP1_N PF06424.12 CDJ52553.1 - 0.043 14.2 16.3 0.064 13.7 16.3 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF4638 PF15472.6 CDJ52553.1 - 0.11 12.2 17.9 0.14 11.8 17.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) PAT1 PF09770.9 CDJ52553.1 - 0.17 10.2 39.1 0.18 10.1 39.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDK5_activator PF03261.15 CDJ52553.1 - 0.23 11.0 14.4 0.25 10.9 14.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF908 PF06012.12 CDJ52553.1 - 0.35 10.2 14.2 0.41 10.0 14.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SLC12 PF03522.15 CDJ52553.1 - 0.4 9.7 21.6 0.46 9.5 21.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4647 PF15504.6 CDJ52553.1 - 0.41 9.7 23.2 0.47 9.5 23.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) GET2 PF08690.10 CDJ52553.1 - 0.45 10.1 27.4 0.66 9.6 27.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 RR_TM4-6 PF06459.12 CDJ52553.1 - 0.72 9.6 23.5 1.1 9.1 23.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.15 CDJ52553.1 - 0.78 9.2 25.4 0.98 8.9 25.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4569 PF15133.6 CDJ52553.1 - 0.81 9.3 22.0 1.1 9.0 22.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Peptidase_S64 PF08192.11 CDJ52553.1 - 1.1 7.7 17.7 1.3 7.4 17.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Hamartin PF04388.12 CDJ52553.1 - 1.5 7.4 21.4 1.7 7.2 21.4 1.0 1 0 0 1 1 1 0 Hamartin protein Vfa1 PF08432.10 CDJ52553.1 - 1.7 9.0 28.3 2.6 8.3 28.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ALMT PF11744.8 CDJ52553.1 - 1.8 7.3 16.4 2 7.1 16.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Activator_LAG-3 PF11498.8 CDJ52553.1 - 2.1 7.2 70.9 2.4 7.0 70.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SAGA-Tad1 PF12767.7 CDJ52553.1 - 2.4 7.8 20.2 3 7.5 20.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit LptF_LptG PF03739.14 CDJ52553.1 - 2.7 6.7 4.6 4.9 5.9 4.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF2052 PF09747.9 CDJ52553.1 - 3.1 7.9 26.1 4.6 7.3 26.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) MDM10 PF12519.8 CDJ52553.1 - 3.8 6.3 19.9 4.9 5.9 19.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Draxin PF15550.6 CDJ52553.1 - 4.5 7.1 21.5 5.7 6.7 21.5 1.1 1 0 0 1 1 1 0 Draxin NPR3 PF03666.13 CDJ52553.1 - 5.2 5.7 19.4 6.3 5.5 19.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Membralin PF09746.9 CDJ52553.1 - 5.4 5.9 12.2 6.8 5.6 12.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein Paramyxo_ncap PF00973.19 CDJ52553.1 - 6.5 5.6 18.1 8 5.3 18.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4207 PF13904.6 CDJ52553.1 - 7.9 6.1 48.0 12 5.4 48.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Cellulose_synt PF03552.14 CDJ52553.1 - 9 4.6 7.1 11 4.3 7.1 1.3 1 0 0 1 1 1 0 Cellulose synthase Hid1 PF12722.7 CDJ52553.1 - 9.5 4.2 24.8 11 4.0 24.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AF-4 PF05110.13 CDJ52554.1 - 0.0005 18.3 10.1 0.0005 18.3 10.1 1.8 2 0 0 2 2 2 1 AF-4 proto-oncoprotein Secretin_N_2 PF07655.13 CDJ52554.1 - 0.051 14.1 8.4 0.16 12.6 8.4 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain RAP1 PF07218.11 CDJ52554.1 - 0.074 11.3 12.4 0.11 10.7 12.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Anth_synt_I_N PF04715.13 CDJ52554.1 - 0.18 12.0 0.1 0.4 10.9 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region DUF4395 PF14340.6 CDJ52554.1 - 6.3 7.1 11.7 12 6.2 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) Spt20 PF12090.8 CDJ52555.1 - 0.82 9.2 3.2 1.3 8.6 3.2 1.3 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ52556.1 - 0.00021 21.6 15.3 0.00021 21.6 15.3 2.3 2 0 0 2 2 2 1 Anti-sigma-K factor rskA SpoIIP PF07454.11 CDJ52556.1 - 0.0055 16.2 1.4 0.0055 16.2 1.4 2.0 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 CDJ52556.1 - 0.0064 16.7 12.6 0.25 11.5 5.0 2.1 2 0 0 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal CIAPIN1 PF05093.13 CDJ52556.1 - 0.013 16.0 11.2 0.095 13.2 5.7 2.3 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Lipase_GDSL PF00657.22 CDJ52556.1 - 0.041 13.8 0.1 0.041 13.8 0.1 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase Suf PF05843.14 CDJ52556.1 - 0.073 13.0 20.7 0.8 9.6 2.4 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ52556.1 - 0.087 12.8 50.1 0.48 10.4 27.6 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ADP_PFK_GK PF04587.15 CDJ52556.1 - 0.13 10.8 5.2 0.15 10.6 3.2 1.8 2 0 0 2 2 2 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Pex14_N PF04695.13 CDJ52556.1 - 0.14 12.8 30.3 1.5 9.5 16.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 CDJ52556.1 - 0.19 12.7 18.8 0.42 11.6 9.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) FAM60A PF15396.6 CDJ52556.1 - 0.22 11.5 8.2 0.67 9.9 2.9 2.0 2 0 0 2 2 2 0 Protein Family FAM60A PA26 PF04636.13 CDJ52556.1 - 0.23 10.3 10.1 0.62 8.9 3.8 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) EIIBC-GUT_N PF03612.14 CDJ52556.1 - 0.24 11.1 10.8 0.73 9.5 4.4 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Rxt3 PF08642.10 CDJ52556.1 - 0.25 12.1 8.1 3.4 8.5 2.7 2.1 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Peroxin-13_N PF04088.13 CDJ52556.1 - 0.55 10.5 8.2 0.98 9.7 1.7 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region G0-G1_switch_2 PF15103.6 CDJ52556.1 - 0.6 10.6 17.1 2.2 8.8 1.5 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Band_3_cyto PF07565.13 CDJ52556.1 - 0.65 9.7 14.8 1.9 8.2 6.7 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain RR_TM4-6 PF06459.12 CDJ52556.1 - 0.68 9.7 14.6 0.75 9.6 7.5 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ52556.1 - 0.71 8.8 7.1 0.77 8.7 2.6 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TERB2 PF15101.6 CDJ52556.1 - 0.73 9.8 26.1 0.21 11.6 11.0 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 ANAPC8 PF04049.13 CDJ52556.1 - 0.86 9.7 11.9 4.4 7.4 0.4 2.1 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 Peptidase_S49_N PF08496.10 CDJ52556.1 - 0.89 9.6 15.3 1.1 9.3 0.3 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SpoVR PF04293.13 CDJ52556.1 - 0.9 8.2 12.0 0.44 9.2 5.7 2.0 2 0 0 2 2 2 0 SpoVR like protein MCU PF04678.13 CDJ52556.1 - 1.3 9.1 15.4 1.6 8.8 5.5 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Tim54 PF11711.8 CDJ52556.1 - 1.3 7.7 14.2 4.1 6.1 0.5 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 EPL1 PF10513.9 CDJ52556.1 - 1.4 9.3 17.4 2.1 8.7 0.3 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF702 PF05142.12 CDJ52556.1 - 1.9 8.9 22.6 5.1 7.6 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Mut7-C PF01927.16 CDJ52556.1 - 1.9 8.5 14.1 0.2 11.8 4.7 2.1 2 0 0 2 2 2 0 Mut7-C RNAse domain Hydin_ADK PF17213.3 CDJ52556.1 - 2.1 8.6 15.1 5.9 7.1 1.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF3295 PF11702.8 CDJ52556.1 - 2.4 7.4 18.1 1.1 8.5 9.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) DUF775 PF05603.12 CDJ52556.1 - 2.4 7.7 18.2 1.8 8.0 7.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF775) DUF3729 PF12526.8 CDJ52556.1 - 2.5 9.7 6.2 1.1 10.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Ctr PF04145.15 CDJ52556.1 - 2.5 8.7 9.8 12 6.5 4.4 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Eapp_C PF10238.9 CDJ52556.1 - 2.9 8.0 17.2 6 6.9 10.7 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein Spt20 PF12090.8 CDJ52556.1 - 3 7.4 58.6 0.77 9.3 31.1 2.1 2 0 0 2 2 2 0 Spt20 family FYDLN_acid PF09538.10 CDJ52556.1 - 3.5 8.4 12.5 0.74 10.5 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Afi1 PF07792.12 CDJ52556.1 - 3.6 8.1 13.7 0.66 10.5 4.7 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ribosomal_60s PF00428.19 CDJ52556.1 - 3.7 8.2 8.1 0.52 10.9 4.0 1.8 2 0 0 2 2 1 0 60s Acidic ribosomal protein DUF1644 PF07800.12 CDJ52556.1 - 3.8 7.6 11.7 19 5.2 8.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) VIT1 PF01988.19 CDJ52556.1 - 3.8 7.3 8.4 19 5.0 0.1 2.2 2 0 0 2 2 2 0 VIT family Consortin_C PF15281.6 CDJ52556.1 - 4.1 7.4 10.5 0.95 9.5 2.3 2.2 2 0 0 2 2 2 0 Consortin C-terminus XRCC4 PF06632.12 CDJ52556.1 - 4.5 6.0 23.5 4.1 6.2 6.3 2.0 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3824 PF12868.7 CDJ52556.1 - 4.9 7.8 16.9 0.73 10.5 10.0 2.1 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) AIF_C PF14721.6 CDJ52556.1 - 5.2 7.4 16.1 4.8 7.5 8.4 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pet20 PF08692.10 CDJ52556.1 - 5.7 7.7 8.7 2.8 8.6 1.6 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Spem1 PF15670.5 CDJ52556.1 - 6.1 6.3 17.7 3.7 7.1 1.6 2.1 2 0 0 2 2 2 0 Spermatid maturation protein 1 HemX PF04375.14 CDJ52556.1 - 6.9 5.9 46.0 0.73 9.1 24.0 2.0 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Maf1 PF09174.10 CDJ52556.1 - 7.2 6.7 11.4 16 5.6 0.4 2.1 2 0 0 2 2 2 0 Maf1 regulator DUF4407 PF14362.6 CDJ52556.1 - 9.1 5.5 33.6 1.9 7.8 17.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FAM176 PF14851.6 CDJ52556.1 - 9.2 5.9 10.8 28 4.4 0.1 2.1 2 0 0 2 2 2 0 FAM176 family Tfb4 PF03850.14 CDJ52557.1 - 4.1 6.8 6.9 5.9 6.3 6.9 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 Spt20 PF12090.8 CDJ52558.1 - 3.6 7.1 16.9 6.4 6.3 16.9 1.4 1 0 0 1 1 1 0 Spt20 family Caldesmon PF02029.15 CDJ52559.1 - 0.00036 19.4 22.9 0.00036 19.4 22.9 2.1 2 0 0 2 2 2 2 Caldesmon DUF966 PF06136.13 CDJ52559.1 - 2.3 7.8 27.2 0.85 9.3 22.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Kelch_5 PF13854.6 CDJ52561.1 - 0.0012 18.8 0.2 0.31 11.1 0.0 3.7 4 0 0 4 4 4 1 Kelch motif RskA PF10099.9 CDJ52561.1 - 0.0018 18.6 0.0 0.0018 18.6 0.0 12.2 2 2 4 8 8 8 2 Anti-sigma-K factor rskA Prolactin_RP PF15172.6 CDJ52561.1 - 0.06 13.0 0.3 0.13 11.9 0.3 1.5 1 0 0 1 1 1 0 Prolactin-releasing peptide Kelch_4 PF13418.6 CDJ52561.1 - 0.061 13.3 0.3 34 4.6 0.0 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ52561.1 - 0.47 10.8 2.8 2.9 8.3 0.0 3.7 5 0 0 5 5 5 0 Galactose oxidase, central domain YL1 PF05764.13 CDJ52562.1 - 5.6e-16 59.4 38.7 5.6e-16 59.4 38.7 3.0 3 0 0 3 3 3 1 YL1 nuclear protein RskA PF10099.9 CDJ52562.1 - 0.0063 16.8 3.6 0.0063 16.8 3.6 4.9 3 2 1 4 4 4 2 Anti-sigma-K factor rskA RcsD_ABL PF16359.5 CDJ52562.1 - 0.059 13.5 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 RcsD-ABL domain Lin-8 PF03353.15 CDJ52562.1 - 2.2 7.8 46.4 2 7.9 25.8 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ52563.1 - 0.00062 19.9 40.6 0.0007 19.7 40.6 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Phage_holin_3_6 PF07332.11 CDJ52563.1 - 0.027 14.5 9.0 0.042 13.9 9.0 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2140 PF09911.9 CDJ52563.1 - 0.15 11.6 4.5 0.27 10.7 4.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF726 PF05277.12 CDJ52563.1 - 0.94 8.3 4.9 1.4 7.7 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF2722 PF10846.8 CDJ52564.1 - 0.00014 20.9 8.6 0.00014 20.9 8.6 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) Connexin PF00029.19 CDJ52564.1 - 0.032 14.0 0.7 0.032 14.0 0.7 2.3 2 0 0 2 2 2 0 Connexin eIF-3_zeta PF05091.12 CDJ52564.1 - 1.4 7.8 30.3 0.04 12.9 7.2 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Shadoo PF14999.6 CDJ52565.1 - 0.002 18.2 5.8 0.002 18.2 5.8 2.4 2 1 0 2 2 2 1 Shadow of prion protein, neuroprotective DUF2722 PF10846.8 CDJ52565.1 - 0.01 14.8 3.6 0.012 14.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52565.1 - 0.014 15.1 9.6 0.015 14.9 9.6 1.1 1 0 0 1 1 1 0 Spt20 family DUF4383 PF14325.6 CDJ52565.1 - 0.028 14.7 0.5 0.028 14.7 0.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) DUF2784 PF10861.8 CDJ52565.1 - 0.03 14.4 0.3 0.044 13.8 0.3 1.4 1 1 0 1 1 1 0 Protein of Unknown function (DUF2784) RAB3GAP2_N PF14655.6 CDJ52565.1 - 0.13 11.5 2.2 0.14 11.4 2.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SUIM_assoc PF16619.5 CDJ52565.1 - 1.9 8.6 15.0 4.5 7.4 15.0 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 NUDE_C PF04880.13 CDJ52565.1 - 3.3 8.2 8.7 1.1 9.7 5.9 1.5 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region WBP-1 PF11669.8 CDJ52565.1 - 6.7 7.4 6.5 10 6.8 6.5 1.5 1 1 0 1 1 1 0 WW domain-binding protein 1 Ten_N PF06484.12 CDJ52565.1 - 7.1 6.4 10.4 7.4 6.3 10.4 1.0 1 0 0 1 1 1 0 Teneurin Intracellular Region SprA-related PF12118.8 CDJ52566.1 - 3.7 6.6 70.2 5.3 6.1 70.2 1.3 1 1 0 1 1 1 0 SprA-related family UPF0564 PF10595.9 CDJ52566.1 - 6.2 5.8 52.8 8.2 5.4 52.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 PPP4R2 PF09184.11 CDJ52566.1 - 9.4 5.7 40.6 11 5.5 40.6 1.1 1 0 0 1 1 1 0 PPP4R2 Trehalose_PPase PF02358.16 CDJ52567.1 - 7e-28 97.3 0.0 1.1e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase DUF5400 PF17379.2 CDJ52567.1 - 0.27 11.7 2.5 4.9 7.7 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5400) Auxin_canalis PF05703.11 CDJ52568.1 - 0.0028 17.6 18.8 0.0036 17.3 18.8 1.1 1 0 0 1 1 1 1 Auxin canalisation Spt20 PF12090.8 CDJ52568.1 - 0.009 15.6 26.3 0.01 15.5 26.3 1.1 1 0 0 1 1 1 1 Spt20 family DUF4666 PF15697.5 CDJ52568.1 - 0.16 12.6 8.3 0.2 12.3 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) ABC2_membrane_2 PF12679.7 CDJ52568.1 - 0.22 10.8 3.3 0.24 10.6 3.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein NST1 PF13945.6 CDJ52568.1 - 0.35 11.0 18.9 0.46 10.6 18.9 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator TFIIA PF03153.13 CDJ52568.1 - 0.56 10.1 27.9 0.62 10.0 27.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FCP1_C PF09309.10 CDJ52568.1 - 0.76 9.6 13.3 0.91 9.4 13.3 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF4698 PF15769.5 CDJ52568.1 - 0.79 8.7 11.1 0.8 8.7 11.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) DUF4554 PF15091.6 CDJ52568.1 - 1.3 7.8 14.9 1.4 7.7 14.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DUF4366 PF14283.6 CDJ52568.1 - 1.6 8.7 7.3 1.9 8.5 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) BAF1_ABF1 PF04684.13 CDJ52568.1 - 2.4 7.1 17.4 2.7 6.9 17.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DAG_kinase_N PF14513.6 CDJ52568.1 - 2.6 8.2 11.3 2.9 8.1 11.3 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus HGTP_anticodon2 PF12745.7 CDJ52568.1 - 3.7 7.0 16.4 4.1 6.8 16.4 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs CDC45 PF02724.14 CDJ52568.1 - 4.3 5.5 11.4 4.6 5.4 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4736 PF15883.5 CDJ52568.1 - 4.9 6.8 12.2 6.9 6.3 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) Ndc1_Nup PF09531.10 CDJ52568.1 - 5.2 5.6 17.3 5.9 5.5 17.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.13 CDJ52568.1 - 6.2 6.5 9.7 6.4 6.5 9.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Folliculin PF11704.8 CDJ52568.1 - 6.2 6.7 11.5 6.9 6.5 11.5 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Med19 PF10278.9 CDJ52568.1 - 7 6.5 13.0 8.6 6.3 13.0 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Baculo_PP31 PF05311.11 CDJ52568.1 - 7.2 6.0 13.1 8 5.9 13.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CDRT4 PF15213.6 CDJ52568.1 - 7.7 7.1 6.9 9.5 6.8 6.9 1.2 1 1 0 1 1 1 0 CMT1A duplicated region transcript 4 protein DUF853 PF05872.12 CDJ52568.1 - 9.9 4.6 14.6 11 4.4 14.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF4746 PF15928.5 CDJ52569.1 - 0.0074 15.7 5.2 0.0088 15.5 5.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) CDC45 PF02724.14 CDJ52569.1 - 0.0075 14.6 12.7 0.0075 14.6 12.7 1.0 1 0 0 1 1 1 1 CDC45-like protein SARAF PF06682.12 CDJ52569.1 - 0.011 15.4 12.6 0.012 15.2 12.6 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PAT1 PF09770.9 CDJ52569.1 - 0.085 11.1 28.5 0.092 11.0 28.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ52569.1 - 0.13 11.0 15.4 0.13 11.0 15.4 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 CDJ52569.1 - 0.2 11.7 9.1 2 8.4 3.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal BORG_CEP PF14957.6 CDJ52569.1 - 0.29 12.3 10.3 0.39 11.9 10.3 1.2 1 0 0 1 1 1 0 Cdc42 effector DUF2828 PF11443.8 CDJ52569.1 - 0.29 9.2 10.3 0.31 9.1 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SLC12 PF03522.15 CDJ52569.1 - 0.52 9.3 14.5 0.57 9.1 14.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ52569.1 - 0.66 9.8 13.5 0.79 9.5 13.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.9 CDJ52569.1 - 0.93 9.6 10.4 1.2 9.2 10.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Exonuc_VII_L PF02601.15 CDJ52569.1 - 1.5 8.3 16.9 1.8 8.1 16.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ndc1_Nup PF09531.10 CDJ52569.1 - 1.6 7.4 13.3 1.7 7.2 13.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup G0-G1_switch_2 PF15103.6 CDJ52569.1 - 1.8 9.0 12.3 3.5 8.1 4.0 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 Vac7 PF12751.7 CDJ52569.1 - 2.1 7.7 11.6 2.7 7.3 11.6 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF4175 PF13779.6 CDJ52569.1 - 2.2 6.1 41.9 2.6 5.9 41.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AAA_26 PF13500.6 CDJ52569.1 - 2.2 8.0 5.8 2.9 7.7 5.8 1.1 1 0 0 1 1 1 0 AAA domain Paramyxo_ncap PF00973.19 CDJ52569.1 - 2.4 6.9 11.9 2.7 6.8 11.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein FAM60A PF15396.6 CDJ52569.1 - 2.8 7.9 12.1 3.5 7.6 12.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A ALMT PF11744.8 CDJ52569.1 - 3.4 6.4 10.9 3.6 6.3 10.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SID-1_RNA_chan PF13965.6 CDJ52569.1 - 4.5 5.6 8.1 5.2 5.3 8.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 CDJ52569.1 - 4.6 6.2 9.9 5.7 5.9 9.9 1.2 1 0 0 1 1 1 0 CLN3 protein Hid1 PF12722.7 CDJ52569.1 - 4.9 5.1 14.6 5.1 5.1 14.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dynactin_p62 PF05502.13 CDJ52569.1 - 5 5.8 11.9 6 5.5 11.9 1.0 1 0 0 1 1 1 0 Dynactin p62 family Rtf2 PF04641.12 CDJ52569.1 - 6.1 6.1 13.1 8 5.7 13.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Coilin_N PF15862.5 CDJ52569.1 - 7.1 6.4 17.6 0.52 10.1 4.9 2.1 2 0 0 2 2 2 0 Coilin N-terminus MPM1 PF17234.2 CDJ52569.1 - 9.4 6.5 19.3 2.2 8.5 2.4 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 MAJIN PF15077.6 CDJ52569.1 - 9.9 5.9 12.1 13 5.5 12.1 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein SPX PF03105.19 CDJ52571.1 - 1.1 9.2 11.3 1.4 8.7 11.3 1.2 1 0 0 1 1 1 0 SPX domain Spt20 PF12090.8 CDJ52571.1 - 7.3 6.1 20.2 1.8 8.1 10.7 2.1 2 0 0 2 2 2 0 Spt20 family FAM184 PF15665.5 CDJ52573.1 - 0.0021 17.9 21.1 0.0025 17.7 21.1 1.1 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B MRP-S27 PF10037.9 CDJ52573.1 - 0.026 13.4 13.0 0.028 13.3 13.0 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 FapA PF03961.13 CDJ52573.1 - 0.078 11.6 9.4 0.085 11.5 9.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A YHYH PF14240.6 CDJ52573.1 - 0.09 12.7 0.3 0.25 11.3 0.3 1.4 1 1 0 1 1 1 0 YHYH protein Jnk-SapK_ap_N PF09744.9 CDJ52573.1 - 0.16 12.2 23.1 0.21 11.8 23.1 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HemX PF04375.14 CDJ52573.1 - 0.17 11.1 39.0 0.2 10.9 39.0 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Exonuc_VII_L PF02601.15 CDJ52573.1 - 0.32 10.5 23.0 0.4 10.2 23.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_S15 PF02129.18 CDJ52573.1 - 1 8.9 15.3 1.2 8.6 15.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LMBR1 PF04791.16 CDJ52573.1 - 1.9 7.3 7.6 1.8 7.4 7.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 CDJ52573.1 - 2.1 7.2 25.0 2.7 6.8 25.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Endonuc_Holl PF10107.9 CDJ52573.1 - 2.7 7.8 12.9 3.8 7.4 12.9 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Phage_portal PF04860.12 CDJ52573.1 - 2.7 7.1 13.4 3.2 6.8 13.4 1.1 1 0 0 1 1 1 0 Phage portal protein DUF4446 PF14584.6 CDJ52573.1 - 3.2 7.7 9.6 4.8 7.2 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF1631 PF07793.11 CDJ52573.1 - 3.5 5.9 38.6 4.2 5.7 38.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) MAJIN PF15077.6 CDJ52573.1 - 4.3 7.1 8.1 4.7 6.9 8.1 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF3450 PF11932.8 CDJ52573.1 - 4.4 6.5 38.1 5.7 6.2 38.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) LCIB_C_CA PF18599.1 CDJ52573.1 - 5.7 6.2 15.0 7.3 5.8 15.0 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases TFIIA PF03153.13 CDJ52573.1 - 6.5 6.6 48.1 8.9 6.2 48.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TALPID3 PF15324.6 CDJ52573.1 - 7.6 4.1 34.7 9.3 3.8 34.7 1.0 1 0 0 1 1 1 0 Hedgehog signalling target SUIM_assoc PF16619.5 CDJ52574.1 - 0.044 13.9 11.6 0.11 12.6 11.6 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Wzy_C_2 PF11846.8 CDJ52574.1 - 0.29 11.0 2.8 1.6 8.6 1.1 2.4 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF2722 PF10846.8 CDJ52575.1 - 0.00025 20.2 1.8 0.00025 20.2 1.8 6.4 7 1 0 7 7 7 3 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ52577.1 - 0.13 11.0 26.2 0.15 10.8 26.2 1.1 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 CDJ52577.1 - 0.62 9.5 6.8 0.81 9.2 6.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Suf PF05843.14 CDJ52577.1 - 0.73 9.8 20.7 0.89 9.5 20.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SLC12 PF03522.15 CDJ52577.1 - 2.4 7.1 20.7 2.9 6.8 20.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ52577.1 - 3.9 7.2 14.4 4.9 6.9 14.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 CDJ52577.1 - 4.7 6.3 16.8 7.2 5.7 16.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 CDJ52577.1 - 6.9 4.7 16.1 7.8 4.6 16.1 1.0 1 0 0 1 1 1 0 Nop14-like family OATP PF03137.20 CDJ52578.1 - 0.046 12.0 0.1 0.046 12.0 0.1 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sin_N PF04801.13 CDJ52578.1 - 0.29 10.3 43.8 0.0088 15.3 9.9 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region DUF4820 PF16091.5 CDJ52578.1 - 1.1 8.6 24.1 0.48 9.8 0.8 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4820) TCP PF03634.13 CDJ52578.1 - 2.3 8.8 27.7 1.1 9.9 2.4 3.5 3 0 0 3 3 3 0 TCP family transcription factor Band_3_cyto PF07565.13 CDJ52578.1 - 2.8 7.7 32.2 0.41 10.4 8.6 3.4 3 1 0 3 3 3 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ52578.1 - 9 4.9 36.2 5.8 5.6 19.2 2.2 2 0 0 2 2 2 0 Presenilin Ribosomal_L12 PF00542.19 CDJ52580.1 - 1.6e-11 44.4 1.5 1.6e-11 44.4 1.5 1.7 2 0 0 2 2 1 1 Ribosomal protein L7/L12 C-terminal domain 7tm_3 PF00003.22 CDJ52580.1 - 0.00012 21.9 7.6 0.00021 21.1 7.6 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR BatD PF13584.6 CDJ52580.1 - 0.00091 18.2 5.4 0.00091 18.2 5.4 3.1 3 1 2 5 5 4 1 Oxygen tolerance SARAF PF06682.12 CDJ52580.1 - 0.0024 17.6 1.0 0.0024 17.6 1.0 3.2 2 2 0 2 2 1 1 SOCE-associated regulatory factor of calcium homoeostasis Phage_holin_3_6 PF07332.11 CDJ52580.1 - 0.003 17.6 8.9 0.003 17.6 8.9 4.3 4 0 0 4 4 3 2 Putative Actinobacterial Holin-X, holin superfamily III Yip1 PF04893.17 CDJ52580.1 - 0.0034 17.1 11.1 0.011 15.4 10.3 3.6 3 1 0 3 3 2 2 Yip1 domain DUF4834 PF16118.5 CDJ52580.1 - 0.0039 18.1 1.0 0.0039 18.1 1.0 3.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4834) Orf78 PF06024.12 CDJ52580.1 - 0.0068 16.7 0.4 0.0068 16.7 0.4 4.4 1 1 2 3 3 2 1 Orf78 (ac78) DUF2207 PF09972.9 CDJ52580.1 - 0.033 13.0 19.5 0.085 11.6 0.0 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) TssO PF17561.2 CDJ52580.1 - 0.043 13.9 1.2 0.043 13.9 1.2 3.6 2 1 2 4 4 3 0 Type VI secretion system, TssO FAM176 PF14851.6 CDJ52580.1 - 0.12 12.0 6.8 1.6 8.4 0.2 2.6 1 1 1 2 2 2 0 FAM176 family EI24 PF07264.11 CDJ52580.1 - 0.23 11.7 16.3 0.081 13.2 13.4 1.7 2 0 0 2 2 1 0 Etoposide-induced protein 2.4 (EI24) DUF3810 PF12725.7 CDJ52580.1 - 0.26 10.6 5.8 0.38 10.1 4.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) CBP_BcsG PF11658.8 CDJ52580.1 - 0.32 9.3 20.7 0.068 11.6 9.5 2.4 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsG DUF2681 PF10883.8 CDJ52580.1 - 0.75 10.2 40.7 0.79 10.2 14.4 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) LPG_synthase_TM PF03706.13 CDJ52580.1 - 1.1 8.8 0.0 1.1 8.8 0.0 3.5 2 1 1 3 3 3 0 Lysylphosphatidylglycerol synthase TM region DUF2070 PF09843.9 CDJ52580.1 - 1.3 7.3 8.4 1.6 7.0 7.6 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Tetraspanin PF00335.20 CDJ52580.1 - 2.1 8.0 18.3 6.4 6.4 0.5 2.6 1 1 1 2 2 2 0 Tetraspanin family Tmpp129 PF10272.9 CDJ52580.1 - 2.6 7.2 17.1 1.4 8.2 12.7 2.0 1 1 1 2 2 2 0 Putative transmembrane protein precursor CLN3 PF02487.17 CDJ52580.1 - 2.7 6.9 20.8 0.28 10.2 1.9 2.6 1 1 1 2 2 2 0 CLN3 protein Choline_transpo PF04515.12 CDJ52580.1 - 6.6 5.8 12.7 78 2.3 13.7 2.2 1 1 1 2 2 2 0 Plasma-membrane choline transporter 7tm_1 PF00001.21 CDJ52580.1 - 7.1 5.9 11.2 20 4.4 11.2 1.8 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) UTP25 PF06862.12 CDJ52582.1 - 2.7e-45 155.1 26.8 2.8e-39 135.2 0.0 3.9 4 0 0 4 4 4 3 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DRY_EERY PF09750.9 CDJ52582.1 - 0.0042 17.4 6.8 0.0042 17.4 6.8 6.4 6 0 0 6 6 6 2 Alternative splicing regulator PAT1 PF09770.9 CDJ52583.1 - 0.18 10.1 22.8 0.19 10.0 22.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 CDJ52583.1 - 2.3 6.8 13.9 2.8 6.5 13.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WBP-1 PF11669.8 CDJ52583.1 - 6.2 7.5 11.3 0.82 10.3 2.8 2.2 2 0 0 2 2 2 0 WW domain-binding protein 1 stn_TNFRSF12A PF12191.8 CDJ52584.1 - 0.12 12.5 0.4 0.12 12.5 0.4 3.0 2 2 1 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MCD PF05292.11 CDJ52584.1 - 0.58 9.7 10.7 1.3 8.6 5.9 2.2 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain Connexin PF00029.19 CDJ52584.1 - 6.8 6.4 14.3 3.5 7.3 9.1 2.1 2 0 0 2 2 2 0 Connexin DnaJ-X PF14308.6 CDJ52584.1 - 8 5.8 18.7 2 7.8 10.7 2.1 2 0 0 2 2 2 0 X-domain of DnaJ-containing ATP-synt_ab_N PF02874.23 CDJ52585.1 - 0.00068 20.1 0.3 0.0011 19.5 0.3 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CDJ52585.1 - 0.061 13.5 0.1 0.094 12.9 0.1 1.2 1 0 0 1 1 1 0 HAS barrel domain DUF2890 PF11081.8 CDJ52585.1 - 0.19 11.8 2.2 0.23 11.5 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF2967 PF11179.8 CDJ52585.1 - 1.5 6.8 9.6 1.7 6.7 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) PTS_EIIC_2 PF13303.6 CDJ52585.1 - 1.7 7.6 8.1 2.2 7.2 8.1 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Ribosomal_60s PF00428.19 CDJ52585.1 - 3.2 8.4 12.3 6.8 7.4 12.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1282 PF06930.12 CDJ52586.1 - 0.0073 16.1 0.4 0.018 14.8 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) MFS_2 PF13347.6 CDJ52586.1 - 0.008 14.8 0.4 0.008 14.8 0.4 1.6 2 0 0 2 2 2 1 MFS/sugar transport protein HTH_15 PF12324.8 CDJ52586.1 - 0.011 15.7 1.6 0.044 13.7 1.6 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase DUF898 PF05987.13 CDJ52586.1 - 5.4 6.0 9.0 0.058 12.4 0.4 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) TMEM171 PF15471.6 CDJ52586.1 - 6 5.8 13.3 0.021 13.8 3.0 2.0 2 0 0 2 2 2 0 Transmembrane protein family 171 Macoilin PF09726.9 CDJ52589.1 - 0.9 8.0 26.4 1.2 7.7 26.4 1.1 1 0 0 1 1 1 0 Macoilin family Utp14 PF04615.13 CDJ52589.1 - 1.7 7.1 17.2 2 6.9 17.2 1.1 1 0 0 1 1 1 0 Utp14 protein RskA PF10099.9 CDJ52589.1 - 2.6 8.3 20.9 3.7 7.8 20.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA HATPase_c PF02518.26 CDJ52590.1 - 1.3e-10 41.7 0.0 2.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ52590.1 - 2.3e-10 40.4 0.7 8.5e-10 38.6 0.1 2.2 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 PF00183.18 CDJ52590.1 - 5e-09 35.6 11.9 7.9e-09 34.9 11.9 1.2 1 0 0 1 1 1 1 Hsp90 protein ORC2 PF04084.14 CDJ52591.1 - 0.0043 16.0 3.2 0.0043 16.0 3.2 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Peptidase_S49_N PF08496.10 CDJ52591.1 - 0.027 14.5 11.1 0.039 14.0 11.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TCRP1 PF14944.6 CDJ52591.1 - 0.04 13.9 3.1 0.048 13.6 3.1 1.1 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 MecA PF05389.12 CDJ52591.1 - 0.081 12.5 7.2 0.076 12.6 7.2 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) RskA PF10099.9 CDJ52591.1 - 0.12 12.6 17.1 0.17 12.2 17.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TERB2 PF15101.6 CDJ52591.1 - 0.16 12.0 15.5 0.23 11.5 15.5 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SprA-related PF12118.8 CDJ52591.1 - 0.26 10.4 26.7 0.31 10.1 26.7 1.1 1 0 0 1 1 1 0 SprA-related family MMR1 PF08505.10 CDJ52591.1 - 0.43 10.8 16.3 0.5 10.6 16.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DDHD PF02862.17 CDJ52591.1 - 0.52 10.4 10.7 0.62 10.2 10.7 1.2 1 0 0 1 1 1 0 DDHD domain Connexin PF00029.19 CDJ52591.1 - 0.7 9.6 4.9 0.66 9.7 4.9 1.1 1 0 0 1 1 1 0 Connexin EIIBC-GUT_N PF03612.14 CDJ52591.1 - 0.9 9.2 9.9 1.2 8.8 9.9 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus eIF-3_zeta PF05091.12 CDJ52591.1 - 0.95 8.4 14.2 0.96 8.3 14.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EOS1 PF12326.8 CDJ52591.1 - 1.2 9.1 4.3 1.2 9.1 4.3 1.2 1 0 0 1 1 1 0 N-glycosylation protein TFIIA PF03153.13 CDJ52591.1 - 1.3 9.0 36.4 1.5 8.7 36.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 CDJ52591.1 - 1.6 6.5 10.3 1.6 6.6 10.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Maf1 PF09174.10 CDJ52591.1 - 2 8.6 10.1 2.6 8.2 10.1 1.2 1 0 0 1 1 1 0 Maf1 regulator Exonuc_VII_L PF02601.15 CDJ52591.1 - 2 7.9 20.2 5.4 6.5 20.2 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit RR_TM4-6 PF06459.12 CDJ52591.1 - 2.3 8.0 12.8 2.6 7.8 12.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 OrfB_IS605 PF01385.19 CDJ52591.1 - 2.5 8.3 10.4 6.1 7.1 10.3 1.7 1 1 0 1 1 1 0 Probable transposase Neur_chan_memb PF02932.16 CDJ52591.1 - 3.2 7.8 9.5 3.4 7.7 9.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ52591.1 - 3.2 7.7 17.2 3.7 7.4 17.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Consortin_C PF15281.6 CDJ52591.1 - 4.1 7.4 6.1 6.3 6.8 6.1 1.4 1 0 0 1 1 1 0 Consortin C-terminus Pex26 PF07163.12 CDJ52591.1 - 5.5 6.2 15.1 9.7 5.4 15.1 1.4 1 0 0 1 1 1 0 Pex26 protein Presenilin PF01080.17 CDJ52591.1 - 6.4 5.4 15.8 6.8 5.4 15.8 1.1 1 0 0 1 1 1 0 Presenilin MDM31_MDM32 PF08118.11 CDJ52591.1 - 9.3 4.8 11.1 11 4.6 11.1 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins CCSAP PF15748.5 CDJ52592.1 - 0.0022 18.2 22.7 0.0024 18.1 22.7 1.0 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated Spt20 PF12090.8 CDJ52592.1 - 0.053 13.1 39.7 0.06 12.9 39.7 1.1 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 CDJ52592.1 - 0.19 11.3 29.7 0.3 10.7 29.7 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2967 PF11179.8 CDJ52592.1 - 0.28 9.2 23.7 0.33 9.0 23.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) TFIIA PF03153.13 CDJ52592.1 - 0.34 10.8 31.8 0.37 10.7 31.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTU2 PF10288.9 CDJ52592.1 - 0.36 11.1 15.5 0.46 10.7 15.5 1.3 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 STAC2_u1 PF16664.5 CDJ52592.1 - 0.74 10.3 14.6 0.88 10.0 14.6 1.1 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Spem1 PF15670.5 CDJ52592.1 - 0.84 9.2 15.7 0.94 9.0 15.7 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 Coiled-coil_56 PF09813.9 CDJ52592.1 - 1.1 9.4 12.7 1.4 9.0 12.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Velvet PF11754.8 CDJ52592.1 - 1.2 9.1 20.1 1.3 8.9 20.1 1.0 1 0 0 1 1 1 0 Velvet factor Pex14_N PF04695.13 CDJ52592.1 - 1.9 9.1 22.7 2.4 8.8 22.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2126 PF09899.9 CDJ52592.1 - 2 6.4 10.5 2.2 6.3 10.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF853 PF05872.12 CDJ52592.1 - 2.9 6.4 14.9 3 6.3 14.9 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FTZ PF03867.14 CDJ52592.1 - 3.5 7.1 15.9 4.1 6.9 15.9 1.0 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Bul1_N PF04425.12 CDJ52592.1 - 3.8 6.2 14.5 4.1 6.1 14.5 1.0 1 0 0 1 1 1 0 Bul1 N terminus PA26 PF04636.13 CDJ52592.1 - 5.6 5.8 13.5 6.2 5.6 13.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MTBP_C PF14920.6 CDJ52592.1 - 7.1 6.3 22.1 8.4 6.1 22.1 1.0 1 0 0 1 1 1 0 MDM2-binding CobT PF06213.12 CDJ52592.1 - 7.1 5.9 24.5 7.9 5.8 24.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIP PF07454.11 CDJ52592.1 - 7.9 5.8 18.2 8.5 5.7 18.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) MMM1 PF10296.9 CDJ52592.1 - 8.3 5.4 12.1 9.3 5.2 12.1 1.0 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Spore_coat_CotO PF14153.6 CDJ52592.1 - 8.7 6.2 20.8 9.7 6.1 20.8 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DnaJ PF00226.31 CDJ52593.1 - 7e-08 32.5 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 CDJ52594.1 - 4.7e-16 58.4 0.0 7.5e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ52594.1 - 0.00024 20.7 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ52594.1 - 0.0014 18.7 0.0 0.0027 17.8 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 CDJ52594.1 - 6 7.1 8.3 0.53 10.5 0.5 2.3 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 CDJ52596.1 - 1.5e-17 63.2 0.0 2.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 CDJ52596.1 - 1.1e-11 44.6 2.1 3.2e-11 43.1 2.1 1.8 1 0 0 1 1 1 1 WW domain RNA_bind PF08675.11 CDJ52596.1 - 0.0038 17.2 0.1 0.0075 16.3 0.1 1.6 1 1 0 1 1 1 1 RNA binding domain DUF2722 PF10846.8 CDJ52597.1 - 0.00039 19.5 13.0 0.00039 19.5 13.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52597.1 - 0.0033 17.1 40.1 0.21 11.2 2.9 2.6 2 0 0 2 2 2 2 Spt20 family RskA PF10099.9 CDJ52597.1 - 0.0069 16.7 14.2 0.0069 16.7 14.2 9.4 2 2 4 6 6 1 1 Anti-sigma-K factor rskA EPL1 PF10513.9 CDJ52597.1 - 0.075 13.4 11.3 0.19 12.1 5.9 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like TMEM171 PF15471.6 CDJ52597.1 - 0.29 10.1 3.7 1.2 8.1 3.7 2.0 1 0 0 1 1 1 0 Transmembrane protein family 171 MDM31_MDM32 PF08118.11 CDJ52597.1 - 0.75 8.4 5.2 1.7 7.2 5.2 1.5 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins NST1 PF13945.6 CDJ52597.1 - 0.79 9.8 15.8 0.23 11.5 5.5 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF572 PF04502.13 CDJ52597.1 - 0.95 9.0 15.7 1.2 8.7 5.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) SpoIIP PF07454.11 CDJ52597.1 - 3 7.2 10.2 0.13 11.7 4.4 1.6 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) MMR1 PF08505.10 CDJ52597.1 - 3.6 7.8 11.6 0.28 11.5 4.8 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF4834 PF16118.5 CDJ52597.1 - 9.9 7.2 17.2 3.6 8.6 11.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4179 PF13786.6 CDJ52598.1 - 0.021 15.3 0.1 1.6 9.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Shadoo PF14999.6 CDJ52598.1 - 0.17 12.0 14.5 1.1 9.4 2.7 2.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective PRIMA1 PF16101.5 CDJ52598.1 - 0.29 11.2 4.2 0.93 9.5 4.2 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Activator_LAG-3 PF11498.8 CDJ52599.1 - 2e-07 30.4 56.2 0.00034 19.7 32.4 2.3 2 0 0 2 2 2 2 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ52599.1 - 0.00066 19.4 16.5 0.00066 19.4 16.5 3.1 3 0 0 3 3 3 2 Spt20 family TCP PF03634.13 CDJ52599.1 - 0.95 10.0 33.9 0.29 11.7 11.7 3.3 3 0 0 3 3 3 0 TCP family transcription factor Lin-8 PF03353.15 CDJ52599.1 - 1.5 8.3 39.8 0.5 9.9 20.3 2.1 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ52599.1 - 7.8 6.0 47.0 6.1 6.4 0.1 3.4 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein FAM199X PF15814.5 CDJ52600.1 - 0.0049 16.0 20.3 0.0059 15.7 20.3 1.1 1 0 0 1 1 1 1 Protein family FAM199X NAM-associated PF14303.6 CDJ52600.1 - 0.0097 16.6 16.7 0.013 16.3 16.7 1.1 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Caldesmon PF02029.15 CDJ52600.1 - 0.024 13.4 14.2 0.028 13.2 14.2 1.0 1 0 0 1 1 1 0 Caldesmon rRNA_processing PF08524.11 CDJ52600.1 - 0.05 13.6 18.2 0.064 13.3 18.2 1.1 1 0 0 1 1 1 0 rRNA processing MMR1 PF08505.10 CDJ52600.1 - 0.051 13.9 24.0 0.059 13.7 24.0 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 CDJ52600.1 - 0.064 13.2 29.6 0.077 13.0 29.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ52600.1 - 0.069 13.0 10.8 0.081 12.7 10.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ52600.1 - 0.1 11.5 13.6 0.11 11.5 13.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PA26 PF04636.13 CDJ52600.1 - 0.13 11.1 11.5 0.15 11.0 11.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Nop53 PF07767.11 CDJ52600.1 - 0.21 10.9 16.7 0.25 10.7 16.7 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CCSAP PF15748.5 CDJ52600.1 - 0.21 11.7 20.7 0.25 11.5 20.7 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated NARP1 PF12569.8 CDJ52600.1 - 0.25 10.2 8.0 0.28 10.1 8.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.16 CDJ52600.1 - 0.28 11.2 12.4 0.33 11.0 12.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4746 PF15928.5 CDJ52600.1 - 0.28 10.5 5.3 0.29 10.5 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Suf PF05843.14 CDJ52600.1 - 0.31 11.0 17.5 0.35 10.8 17.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FHIPEP PF00771.20 CDJ52600.1 - 0.32 9.4 4.4 0.39 9.1 4.4 1.1 1 0 0 1 1 1 0 FHIPEP family Velvet PF11754.8 CDJ52600.1 - 0.33 10.9 18.7 0.41 10.5 18.7 1.1 1 0 0 1 1 1 0 Velvet factor DUF3682 PF12446.8 CDJ52600.1 - 0.37 11.3 32.6 0.64 10.5 32.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) SprA-related PF12118.8 CDJ52600.1 - 0.41 9.7 30.5 0.58 9.2 30.5 1.2 1 0 0 1 1 1 0 SprA-related family Raftlin PF15250.6 CDJ52600.1 - 0.42 9.3 15.8 0.46 9.2 15.8 1.0 1 0 0 1 1 1 0 Raftlin TCP PF03634.13 CDJ52600.1 - 0.54 10.8 18.3 0.69 10.5 18.3 1.1 1 0 0 1 1 1 0 TCP family transcription factor DUF4614 PF15391.6 CDJ52600.1 - 0.57 10.2 24.2 0.76 9.8 24.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF572 PF04502.13 CDJ52600.1 - 0.6 9.7 16.6 0.66 9.5 16.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) CASP_C PF08172.12 CDJ52600.1 - 0.6 9.4 19.7 0.77 9.1 19.7 1.0 1 0 0 1 1 1 0 CASP C terminal Band_3_cyto PF07565.13 CDJ52600.1 - 0.68 9.7 12.5 0.91 9.3 12.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SOBP PF15279.6 CDJ52600.1 - 0.74 10.4 19.5 0.79 10.3 19.5 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Roughex PF06020.11 CDJ52600.1 - 1.1 8.3 9.5 1.3 8.1 9.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein V_ATPase_I PF01496.19 CDJ52600.1 - 1.1 7.1 12.4 1.3 6.8 12.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ52600.1 - 1.1 7.9 22.1 1.4 7.6 22.1 1.0 1 0 0 1 1 1 0 Presenilin Dicty_REP PF05086.12 CDJ52600.1 - 1.2 7.1 12.7 1.2 7.0 12.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SMYLE_N PF18615.1 CDJ52600.1 - 1.6 8.3 15.7 1.8 8.1 15.7 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Ndc1_Nup PF09531.10 CDJ52600.1 - 1.8 7.2 18.7 1.9 7.1 18.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.9 CDJ52600.1 - 1.8 8.1 36.8 6.2 6.4 36.8 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sec62 PF03839.16 CDJ52600.1 - 1.9 7.9 9.9 2.3 7.7 9.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SLC12 PF03522.15 CDJ52600.1 - 2 7.3 15.4 2.1 7.3 15.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Dsh_C PF12316.8 CDJ52600.1 - 2.4 8.5 23.3 3 8.2 23.3 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4175 PF13779.6 CDJ52600.1 - 2.5 5.9 23.1 2.7 5.8 23.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RAP1 PF07218.11 CDJ52600.1 - 2.6 6.2 11.4 2.7 6.2 11.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDC45 PF02724.14 CDJ52600.1 - 2.6 6.2 16.4 3.1 6.0 16.4 1.0 1 0 0 1 1 1 0 CDC45-like protein MCM_bind PF09739.9 CDJ52600.1 - 2.6 6.4 17.3 3.1 6.1 17.3 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PPP4R2 PF09184.11 CDJ52600.1 - 2.7 7.5 15.3 3.1 7.3 15.3 1.0 1 0 0 1 1 1 0 PPP4R2 DivIC PF04977.15 CDJ52600.1 - 2.9 7.7 15.8 4.4 7.1 15.8 1.3 1 0 0 1 1 1 0 Septum formation initiator ASD2 PF08687.11 CDJ52600.1 - 2.9 7.4 16.5 3.3 7.2 16.5 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Hydin_ADK PF17213.3 CDJ52600.1 - 2.9 8.1 17.5 3.7 7.8 17.5 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF775 PF05603.12 CDJ52600.1 - 3.3 7.2 15.2 4.3 6.8 15.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) LEA_3 PF03242.13 CDJ52600.1 - 3.4 8.5 9.0 5 7.9 9.0 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF3533 PF12051.8 CDJ52600.1 - 3.7 6.4 11.6 4 6.2 11.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Hid1 PF12722.7 CDJ52600.1 - 4.3 5.3 19.4 4.7 5.2 19.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2981 PF11200.8 CDJ52600.1 - 4.4 7.0 6.4 5.4 6.7 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4407 PF14362.6 CDJ52600.1 - 4.4 6.6 12.5 5.1 6.4 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Menin PF05053.13 CDJ52600.1 - 6.4 5.0 16.3 7.4 4.8 16.3 1.0 1 0 0 1 1 1 0 Menin XRN_M PF17846.1 CDJ52600.1 - 6.5 5.6 11.4 7.4 5.4 11.4 1.0 1 0 0 1 1 1 0 Xrn1 helical domain GREB1 PF15782.5 CDJ52600.1 - 6.6 3.7 22.5 7.3 3.6 22.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Paramyxo_ncap PF00973.19 CDJ52600.1 - 6.6 5.5 10.9 7.4 5.4 10.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Peptidase_S64 PF08192.11 CDJ52600.1 - 7.8 4.9 19.1 9.2 4.6 19.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 Apt1 PF10351.9 CDJ52600.1 - 9.6 4.9 20.9 12 4.6 20.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3043 PF11241.8 CDJ52600.1 - 9.8 6.2 8.7 12 5.9 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) MAJIN PF15077.6 CDJ52600.1 - 9.9 5.9 14.5 12 5.7 14.5 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein MscS_TM PF12794.7 CDJ52600.1 - 10 4.9 8.6 12 4.6 8.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 ASFV_J13L PF05568.11 CDJ52601.1 - 2.8 7.7 7.6 4.7 6.9 7.6 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein RLL PF10036.9 CDJ52603.1 - 2.1e-25 90.0 8.8 2.1e-25 90.0 8.8 2.0 2 0 0 2 2 2 1 RNA transcription, translation and transport factor protein Spt20 PF12090.8 CDJ52603.1 - 0.0016 18.1 38.9 0.0034 17.0 8.1 2.2 2 0 0 2 2 2 2 Spt20 family DUF4834 PF16118.5 CDJ52603.1 - 0.11 13.5 16.2 0.12 13.3 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2072 PF09845.9 CDJ52603.1 - 0.16 12.2 6.4 0.37 11.0 0.4 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein Suf PF05843.14 CDJ52603.1 - 0.58 10.1 17.9 0.54 10.2 2.7 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1980 PF09323.10 CDJ52603.1 - 0.72 9.7 4.7 6.6 6.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) MRP-L28 PF09812.9 CDJ52603.1 - 1.1 9.4 19.1 0.58 10.3 4.6 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 FAM60A PF15396.6 CDJ52603.1 - 1.4 8.8 8.0 7.9 6.4 2.2 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Connexin PF00029.19 CDJ52603.1 - 1.6 8.4 7.2 4.7 6.9 0.3 2.1 2 0 0 2 2 2 0 Connexin RR_TM4-6 PF06459.12 CDJ52603.1 - 2.1 8.1 11.2 4.5 7.0 2.5 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 CDJ52603.1 - 2.3 8.4 11.9 2 8.6 2.2 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CTU2 PF10288.9 CDJ52603.1 - 2.8 8.2 14.1 2.6 8.3 3.6 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 eIF_4EBP PF05456.11 CDJ52603.1 - 3.3 7.7 11.3 13 5.7 0.4 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Orf78 PF06024.12 CDJ52603.1 - 4.1 7.8 8.6 5.2 7.4 0.3 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Rpp20 PF12328.8 CDJ52603.1 - 5.4 7.0 11.4 3.3 7.7 1.8 2.3 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P CDH1_2_SANT_HL1 PF18375.1 CDJ52603.1 - 7.3 7.3 8.5 23 5.8 0.5 2.3 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 ACDC PF14733.6 CDJ52605.1 - 3.6e-10 40.0 0.1 1.9e-09 37.7 0.1 2.4 1 1 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ52605.1 - 0.019 15.2 0.0 0.019 15.2 0.0 5.1 5 0 0 5 5 5 0 AP2 domain DUF3245 PF11595.8 CDJ52606.1 - 0.0085 16.6 10.8 0.01 16.3 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) RF-1 PF00472.20 CDJ52606.1 - 0.04 13.8 18.7 0.05 13.5 18.7 1.2 1 0 0 1 1 1 0 RF-1 domain Activator_LAG-3 PF11498.8 CDJ52606.1 - 0.34 9.8 51.8 0.4 9.6 51.8 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FapA PF03961.13 CDJ52606.1 - 0.46 9.0 6.3 0.49 8.9 6.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A NPR3 PF03666.13 CDJ52606.1 - 0.61 8.8 13.7 0.75 8.5 13.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CLN3 PF02487.17 CDJ52606.1 - 1.7 7.6 7.8 1.6 7.7 7.8 1.1 1 0 0 1 1 1 0 CLN3 protein eIF-3_zeta PF05091.12 CDJ52606.1 - 1.8 7.5 21.0 1.9 7.4 21.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ52606.1 - 1.8 8.5 41.2 2 8.3 41.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4569 PF15133.6 CDJ52606.1 - 2.8 7.6 15.5 3 7.5 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Presenilin PF01080.17 CDJ52606.1 - 2.9 6.5 19.6 3.3 6.4 19.6 1.0 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 CDJ52606.1 - 3.4 7.0 7.6 3.4 7.0 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 CDJ52606.1 - 3.8 7.3 14.8 4.2 7.1 14.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1682 PF07946.14 CDJ52606.1 - 4 6.6 16.6 4.1 6.5 16.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SpoIIP PF07454.11 CDJ52606.1 - 4.5 6.6 11.9 5.1 6.5 11.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EOS1 PF12326.8 CDJ52606.1 - 5 7.0 6.8 6 6.8 6.8 1.3 1 0 0 1 1 1 0 N-glycosylation protein BORG_CEP PF14957.6 CDJ52606.1 - 5.1 8.3 9.5 6.1 8.0 9.5 1.1 1 0 0 1 1 1 0 Cdc42 effector Serinc PF03348.15 CDJ52606.1 - 5.2 5.9 7.7 5.4 5.8 7.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) ALMT PF11744.8 CDJ52606.1 - 6.5 5.5 9.2 6.6 5.5 9.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 CDJ52606.1 - 6.5 6.7 12.0 7 6.6 12.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 CDJ52606.1 - 6.7 6.8 12.8 7.7 6.6 12.8 1.1 1 0 0 1 1 1 0 DDHD domain NEMP PF10225.9 CDJ52606.1 - 7.8 6.1 6.8 7.9 6.1 6.8 1.1 1 0 0 1 1 1 0 NEMP family Connexin PF00029.19 CDJ52606.1 - 8 6.1 11.7 8.7 6.0 11.7 1.1 1 0 0 1 1 1 0 Connexin Peroxin-13_N PF04088.13 CDJ52606.1 - 8.3 6.7 8.4 11 6.2 8.4 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region MRP-S27 PF10037.9 CDJ52606.1 - 9.1 5.0 18.1 9.9 4.9 18.1 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF1980 PF09323.10 CDJ52606.1 - 9.9 6.0 7.1 10 6.0 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SR-25 PF10500.9 CDJ52607.1 - 0.0027 17.4 24.4 0.0027 17.4 24.4 2.9 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 CDJ52607.1 - 0.0029 17.4 6.4 0.0029 17.4 6.4 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein SMAP PF15477.6 CDJ52607.1 - 0.013 16.4 0.2 0.013 16.4 0.2 3.6 1 1 1 2 2 2 0 Small acidic protein family DUF4050 PF13259.6 CDJ52607.1 - 0.063 13.6 14.4 0.65 10.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Adaptin_binding PF10199.9 CDJ52607.1 - 0.071 13.7 10.8 0.096 13.3 2.8 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Roughex PF06020.11 CDJ52607.1 - 0.41 9.7 10.8 0.56 9.2 1.5 2.0 2 0 0 2 2 2 0 Drosophila roughex protein DUF92 PF01940.16 CDJ52607.1 - 0.46 9.9 8.3 0.7 9.3 8.3 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF92 FHIPEP PF00771.20 CDJ52607.1 - 3.8 5.9 7.3 0.37 9.2 1.9 1.8 1 1 1 2 2 2 0 FHIPEP family Med8 PF10232.9 CDJ52607.1 - 8.4 5.9 12.2 0.56 9.8 3.7 2.1 1 1 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 LRR19-TM PF15176.6 CDJ52608.1 - 0.019 15.0 0.8 0.025 14.6 0.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain SR-25 PF10500.9 CDJ52608.1 - 0.024 14.2 14.6 0.03 13.9 14.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2232 PF09991.9 CDJ52608.1 - 0.028 13.6 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) TFIIA PF03153.13 CDJ52608.1 - 0.13 12.3 30.6 0.15 12.1 30.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.15 CDJ52608.1 - 0.35 9.7 5.9 0.37 9.7 5.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.12 CDJ52608.1 - 1.4 8.7 13.8 1.5 8.6 13.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MAJIN PF15077.6 CDJ52608.1 - 2.2 8.0 7.7 2.5 7.8 7.7 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein RskA PF10099.9 CDJ52608.1 - 2.3 8.5 36.8 0.25 11.6 18.6 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DDHD PF02862.17 CDJ52608.1 - 3.8 7.6 11.0 4.2 7.5 11.0 1.2 1 0 0 1 1 1 0 DDHD domain SelP_N PF04592.14 CDJ52608.1 - 3.9 6.8 13.6 4.6 6.6 13.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SR-25 PF10500.9 CDJ52609.1 - 0.49 10.0 47.9 0.32 10.6 0.4 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF2615 PF11027.8 CDJ52609.1 - 0.73 10.0 8.2 0.055 13.6 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF4179 PF13786.6 CDJ52609.1 - 1.7 9.2 13.6 1.7 9.2 1.0 3.6 2 2 2 4 4 4 0 Domain of unknown function (DUF4179) FAM76 PF16046.5 CDJ52609.1 - 4 6.7 11.7 0.063 12.6 0.3 2.2 2 1 0 2 2 2 0 FAM76 protein RskA PF10099.9 CDJ52610.1 - 8.6e-05 22.9 14.1 0.00017 21.9 13.1 1.7 2 0 0 2 2 2 1 Anti-sigma-K factor rskA MID_MedPIWI PF18296.1 CDJ52610.1 - 0.13 12.1 10.7 0.22 11.3 10.7 1.3 1 1 0 1 1 1 0 MID domain of medPIWI SR-25 PF10500.9 CDJ52611.1 - 0.0016 18.1 10.7 0.0016 18.1 10.7 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ52611.1 - 6.1 7.2 15.5 0.35 11.2 5.1 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain IMUP PF15761.5 CDJ52611.1 - 8 7.2 15.7 0.34 11.6 7.8 2.2 2 1 0 2 2 2 0 Immortalisation up-regulated protein DUF3273 PF11677.8 CDJ52612.1 - 5.1e-06 26.0 0.0 6.5e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF2780 PF11075.8 CDJ52612.1 - 0.0094 16.1 7.8 0.012 15.8 7.8 1.1 1 0 0 1 1 1 1 Protein of unknown function VcgC/VcgE (DUF2780) Chorion_2 PF03964.15 CDJ52612.1 - 0.012 16.4 3.7 0.018 15.8 3.7 1.3 1 0 0 1 1 1 0 Chorion family 2 DUF3138 PF11336.8 CDJ52612.1 - 0.099 11.2 7.4 0.12 10.9 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RskA PF10099.9 CDJ52612.1 - 0.17 12.2 9.3 4.6 7.5 0.0 1.9 1 1 1 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ52612.1 - 0.83 9.6 17.3 0.97 9.4 17.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3273 PF11677.8 CDJ52613.1 - 3.7e-12 46.1 0.4 4.5e-12 45.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) SUIM_assoc PF16619.5 CDJ52614.1 - 1.4e-05 25.0 2.5 0.0042 17.1 4.6 11.9 8 4 1 9 9 9 3 Unstructured region C-term to UIM in Ataxin3 Sin_N PF04801.13 CDJ52614.1 - 6.8e-05 22.3 0.0 6.8e-05 22.3 0.0 4.7 3 2 1 4 4 4 2 Sin-like protein conserved region RskA PF10099.9 CDJ52614.1 - 0.00068 20.0 11.8 0.00068 20.0 11.8 12.5 1 1 8 10 10 10 3 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ52614.1 - 0.0088 15.7 15.2 0.0088 15.7 15.2 7.2 6 1 0 6 6 6 4 Spt20 family MT-A70 PF05063.14 CDJ52615.1 - 7.5e-15 55.3 0.0 2.2e-11 44.0 0.0 2.9 1 1 1 2 2 2 2 MT-A70 SUIM_assoc PF16619.5 CDJ52615.1 - 8.7e-05 22.5 0.3 8.7e-05 22.5 0.3 9.7 3 2 2 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ52615.1 - 0.0045 16.6 6.5 0.0045 16.6 6.5 3.2 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein GBV-C_env PF12786.7 CDJ52616.1 - 2.9 6.5 3.7 1.1 7.8 1.0 1.6 2 0 0 2 2 2 0 GB virus C genotype envelope RRM_1 PF00076.22 CDJ52617.1 - 0.07 13.0 0.0 4.7 7.1 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V-ATPase_G PF03179.15 CDJ52618.1 - 2.9e-07 31.0 8.4 7.3e-07 29.7 8.4 1.6 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit PAS_7 PF12860.7 CDJ52618.1 - 0.037 14.2 0.7 0.11 12.7 0.7 1.8 1 0 0 1 1 1 0 PAS fold HisK_sensor PF18698.1 CDJ52618.1 - 0.13 12.6 1.0 0.53 10.7 0.6 2.0 2 0 0 2 2 2 0 Histidine kinase sensor domain Ribosomal_L34 PF00468.17 CDJ52618.1 - 0.77 9.8 0.1 0.77 9.8 0.1 2.9 3 0 0 3 3 3 0 Ribosomal protein L34 V-ATPase_G_2 PF16999.5 CDJ52618.1 - 1.4 9.4 18.9 0.051 14.0 12.2 2.2 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 CDJ52618.1 - 2.8 7.3 16.0 0.3 10.5 11.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) PNK3P PF08645.11 CDJ52619.1 - 2.2e-37 128.2 0.0 6.6e-23 81.2 0.0 2.5 1 1 1 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CDJ52619.1 - 2.8e-08 34.1 0.8 3.3e-06 27.3 0.1 3.1 2 1 0 2 2 2 1 AAA domain tRNA_lig_kinase PF08303.11 CDJ52619.1 - 8.1e-05 22.8 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_16 PF13191.6 CDJ52619.1 - 0.0021 18.5 0.0 0.0056 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 CDJ52619.1 - 0.012 15.9 0.2 0.11 12.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ52619.1 - 0.017 15.0 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CDJ52619.1 - 0.026 14.2 0.0 0.22 11.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CDJ52619.1 - 0.032 14.7 0.2 0.27 11.7 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 CDJ52619.1 - 0.032 14.8 0.0 0.078 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CDJ52619.1 - 0.037 13.9 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Ploopntkinase3 PF18751.1 CDJ52619.1 - 0.045 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 CDJ52619.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDJ52619.1 - 0.079 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CDJ52619.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CDJ52619.1 - 0.12 11.7 0.1 4 6.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family KTI12 PF08433.10 CDJ52619.1 - 0.33 10.4 2.0 6.5 6.1 2.0 2.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 CWC25 PF12542.8 CDJ52619.1 - 2 9.4 13.1 0.15 13.0 1.3 3.4 3 0 0 3 3 3 0 Pre-mRNA splicing factor PKD_channel PF08016.12 CDJ52619.1 - 3.5 6.2 38.4 0.13 10.9 11.2 3.6 4 0 0 4 4 4 0 Polycystin cation channel Fibrinogen_BP PF08017.11 CDJ52620.1 - 1.5e-05 23.7 83.6 1.5e-05 23.7 83.6 2.8 2 1 1 3 3 3 2 Fibrinogen binding protein Cornifin PF02389.15 CDJ52620.1 - 0.0011 19.2 45.9 0.017 15.3 9.1 4.1 1 1 3 4 4 4 4 Cornifin (SPRR) family LapA_dom PF06305.11 CDJ52623.1 - 0.03 14.1 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Peptidase_A2E PF12382.8 CDJ52625.1 - 0.086 12.9 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon peptidase MutS_IV PF05190.18 CDJ52626.1 - 0.21 11.9 0.2 0.21 11.9 0.2 2.3 1 1 1 2 2 2 0 MutS family domain IV Neuregulin PF02158.15 CDJ52626.1 - 1.8 7.9 20.4 0.028 13.8 11.1 2.2 1 1 1 2 2 2 0 Neuregulin intracellular region DUF3801 PF12687.7 CDJ52626.1 - 5.2 7.1 27.4 4 7.5 3.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) DUF5585 PF17823.1 CDJ52626.1 - 6 5.7 18.2 8.6 5.2 18.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) TCP PF03634.13 CDJ52626.1 - 9.2 6.8 21.4 3.2 8.3 2.7 2.4 2 1 0 2 2 2 0 TCP family transcription factor Shisa PF13908.6 CDJ52627.1 - 0.00023 21.5 3.9 0.00028 21.2 3.9 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator NPR3 PF03666.13 CDJ52627.1 - 0.0022 16.8 3.6 0.0022 16.8 3.6 1.0 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 SR-25 PF10500.9 CDJ52627.1 - 0.0096 15.6 15.7 0.012 15.2 15.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Coilin_N PF15862.5 CDJ52627.1 - 0.019 14.7 5.2 0.021 14.6 5.2 1.2 1 0 0 1 1 1 0 Coilin N-terminus Zip PF02535.22 CDJ52627.1 - 0.057 12.6 0.6 0.061 12.5 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 CDJ52627.1 - 0.062 11.7 0.7 0.071 11.5 0.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 O-antigen_lig PF13425.6 CDJ52627.1 - 0.2 10.4 0.0 0.21 10.3 0.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Neur_chan_memb PF02932.16 CDJ52627.1 - 0.89 9.6 4.2 1.1 9.2 4.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 CDJ52627.1 - 1.6 8.7 9.8 1.9 8.5 9.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2749 PF10907.8 CDJ52627.1 - 2.8 8.2 10.7 29 4.9 10.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) Spt20 PF12090.8 CDJ52627.1 - 4.1 6.9 20.3 4.7 6.8 20.3 1.2 1 0 0 1 1 1 0 Spt20 family AIF_C PF14721.6 CDJ52627.1 - 9.7 6.6 10.0 13 6.1 10.0 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TRAPPC9-Trs120 PF08626.11 CDJ52628.1 - 1.3e-06 26.1 1.4 0.00027 18.5 0.0 4.0 4 1 1 5 5 5 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit tRNA-synt_1_2 PF13603.6 CDJ52629.1 - 0.0054 16.3 0.8 0.006 16.1 0.8 1.0 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 RskA PF10099.9 CDJ52629.1 - 0.016 15.5 9.3 0.016 15.5 9.3 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ52629.1 - 0.097 12.7 6.7 0.088 12.8 6.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RsgA_GTPase PF03193.16 CDJ52629.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Spt20 PF12090.8 CDJ52629.1 - 0.27 10.8 7.8 0.28 10.8 7.8 1.1 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ52629.1 - 0.59 10.2 14.5 0.91 9.6 14.5 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF3824 PF12868.7 CDJ52629.1 - 0.92 10.2 8.6 1.1 9.9 8.6 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Med15 PF09606.10 CDJ52629.1 - 1 8.0 12.6 1 8.0 12.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PepSY_2 PF13670.6 CDJ52629.1 - 1 9.4 10.9 1.6 8.8 10.9 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain LPP20 PF02169.16 CDJ52629.1 - 1.9 8.9 9.1 2.2 8.7 9.1 1.1 1 0 0 1 1 1 0 LPP20 lipoprotein DUF2967 PF11179.8 CDJ52629.1 - 2.9 5.9 9.0 3.6 5.6 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF3138 PF11336.8 CDJ52629.1 - 6.1 5.3 9.2 6.3 5.3 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Med3 PF11593.8 CDJ52629.1 - 8.8 5.4 17.3 12 5.0 17.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PIN_8 PF18476.1 CDJ52630.1 - 0.0021 18.0 2.0 0.0021 18.0 2.0 1.8 2 0 0 2 2 2 1 PIN like domain RT_RNaseH PF17917.1 CDJ52630.1 - 0.0061 16.8 1.5 0.02 15.2 1.5 1.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ArAE_2 PF10334.9 CDJ52630.1 - 0.032 14.0 1.0 0.092 12.6 1.0 1.7 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 SUIM_assoc PF16619.5 CDJ52630.1 - 0.19 11.8 31.7 0.47 10.6 5.8 3.9 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ52630.1 - 0.89 9.1 39.6 2.3 7.8 16.6 2.3 2 0 0 2 2 2 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ52630.1 - 0.94 8.4 37.5 0.04 12.9 14.2 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF4813 PF16072.5 CDJ52631.1 - 1.2 8.8 28.2 0.13 11.9 20.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) CH_2 PF06294.11 CDJ52633.1 - 1.5e-18 66.7 0.1 2.2e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CDJ52633.1 - 0.005 16.7 0.0 0.0081 16.0 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain Pex14_N PF04695.13 CDJ52633.1 - 0.57 10.8 17.2 2.3 8.8 10.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SUIM_assoc PF16619.5 CDJ52634.1 - 0.013 15.5 1.4 0.013 15.5 1.4 8.3 8 0 0 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 Adaptin_N PF01602.20 CDJ52635.1 - 3.2e-16 59.0 5.6 5.3e-06 25.3 0.0 3.4 3 1 0 3 3 3 3 Adaptin N terminal region Coatomer_g_Cpla PF16381.5 CDJ52635.1 - 8.5e-15 54.9 0.2 9.2e-14 51.6 0.2 2.6 1 1 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform COP-gamma_platf PF08752.10 CDJ52635.1 - 7.9e-07 29.3 0.0 0.011 15.8 0.0 3.1 3 1 0 3 3 3 2 Coatomer gamma subunit appendage platform subdomain Inj_translocase PF16928.5 CDJ52635.1 - 0.0023 17.5 0.7 0.0023 17.5 0.7 3.9 4 0 0 4 4 4 1 DNA/protein translocase of phage P22 injectosome Coatomer_b_Cpla PF14806.6 CDJ52635.1 - 0.098 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform COX14 PF14880.6 CDJ52636.1 - 6.4e-07 29.1 0.5 8.9e-07 28.7 0.5 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly SR-25 PF10500.9 CDJ52636.1 - 0.24 11.0 18.1 0.29 10.7 18.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC24 PF15669.5 CDJ52636.1 - 0.33 10.8 3.6 0.41 10.5 3.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SDP_N PF12278.8 CDJ52636.1 - 0.58 10.3 4.9 0.73 10.0 4.9 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal DUF4698 PF15769.5 CDJ52636.1 - 1 8.4 6.7 1.3 8.0 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) AF-4 PF05110.13 CDJ52636.1 - 4.4 5.3 21.7 4.7 5.2 21.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.11 CDJ52636.1 - 6.4 4.9 9.7 6.8 4.8 9.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BAF1_ABF1 PF04684.13 CDJ52637.1 - 0.0035 16.5 9.5 0.004 16.3 9.5 1.0 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DUF2232 PF09991.9 CDJ52637.1 - 0.038 13.2 2.1 0.044 12.9 2.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Ribosomal_60s PF00428.19 CDJ52637.1 - 0.048 14.2 14.3 0.086 13.4 14.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein SID-1_RNA_chan PF13965.6 CDJ52637.1 - 0.23 9.8 1.6 0.24 9.7 1.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pex14_N PF04695.13 CDJ52637.1 - 0.26 11.9 20.4 0.32 11.6 20.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ52637.1 - 0.69 9.8 30.7 0.82 9.6 30.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ52637.1 - 1.1 7.9 10.3 1.2 7.8 10.3 1.0 1 0 0 1 1 1 0 Presenilin AAA_23 PF13476.6 CDJ52637.1 - 2 8.8 12.5 2.1 8.8 12.5 1.1 1 0 0 1 1 1 0 AAA domain GET2 PF08690.10 CDJ52637.1 - 2.1 8.0 15.0 2.3 7.8 15.0 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 Activator_LAG-3 PF11498.8 CDJ52637.1 - 2.1 7.2 32.2 2.4 7.0 32.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PAT1 PF09770.9 CDJ52637.1 - 5 5.3 21.9 5.8 5.1 21.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ureide_permease PF07168.11 CDJ52637.1 - 5.5 5.6 5.9 6.4 5.4 5.9 1.0 1 0 0 1 1 1 0 Ureide permease DUF4179 PF13786.6 CDJ52637.1 - 7.1 7.2 8.8 11 6.6 8.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) DUF3824 PF12868.7 CDJ52637.1 - 8.6 7.0 16.8 14 6.3 16.8 1.4 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) O-antigen_lig PF13425.6 CDJ52637.1 - 8.8 5.0 5.4 9.8 4.8 5.4 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein IHABP4_N PF16174.5 CDJ52637.1 - 9.4 6.8 19.0 14 6.3 19.0 1.2 1 1 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal R_equi_Vir PF05526.11 CDJ52637.1 - 9.7 6.0 9.1 12 5.7 9.1 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RskA PF10099.9 CDJ52638.1 - 0.0052 17.1 16.5 0.0052 17.1 16.5 7.2 2 2 2 4 4 4 2 Anti-sigma-K factor rskA MAM33 PF02330.16 CDJ52639.1 - 3.9e-21 76.0 0.0 3.9e-21 76.0 0.0 2.5 1 1 1 2 2 1 1 Mitochondrial glycoprotein Sec16 PF12932.7 CDJ52639.1 - 0.0011 19.5 0.0 0.0018 18.9 0.0 1.5 1 1 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region eIF-3_zeta PF05091.12 CDJ52639.1 - 0.0016 17.5 9.5 0.0016 17.5 9.5 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ52639.1 - 0.0035 16.2 7.4 0.0034 16.2 7.4 1.1 1 0 0 1 1 1 1 Presenilin FemAB PF02388.16 CDJ52639.1 - 0.011 14.7 13.8 0.013 14.4 13.8 1.1 1 0 0 1 1 1 0 FemAB family EOS1 PF12326.8 CDJ52639.1 - 0.039 13.9 1.1 0.041 13.8 1.1 1.2 1 0 0 1 1 1 0 N-glycosylation protein Serinc PF03348.15 CDJ52639.1 - 0.096 11.6 3.0 0.086 11.8 3.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4746 PF15928.5 CDJ52639.1 - 0.12 11.8 6.4 0.14 11.5 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Vma12 PF11712.8 CDJ52639.1 - 0.26 11.3 2.9 0.3 11.2 2.9 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Peroxin-13_N PF04088.13 CDJ52639.1 - 0.33 11.2 8.6 0.51 10.6 8.6 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region AIF_C PF14721.6 CDJ52639.1 - 0.6 10.5 10.6 3.3 8.1 10.2 2.0 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SpoIIP PF07454.11 CDJ52639.1 - 0.89 9.0 13.4 1.1 8.7 13.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 CDJ52639.1 - 1.1 9.2 34.7 1.5 8.7 34.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1645 PF07816.11 CDJ52639.1 - 1.5 9.4 11.4 3.1 8.4 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Pex14_N PF04695.13 CDJ52639.1 - 2 9.0 23.3 0.72 10.5 20.0 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CobT PF06213.12 CDJ52639.1 - 3.4 7.0 23.4 5.1 6.4 23.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT G0-G1_switch_2 PF15103.6 CDJ52639.1 - 3.6 8.0 9.6 5.6 7.4 9.6 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 Ctr PF04145.15 CDJ52639.1 - 3.8 8.1 8.0 2.6 8.6 6.4 1.6 2 0 0 2 2 2 0 Ctr copper transporter family DUF4834 PF16118.5 CDJ52639.1 - 4.1 8.4 17.8 1.6 9.7 15.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) DUF4175 PF13779.6 CDJ52639.1 - 4.5 5.1 33.3 5.2 4.8 33.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Band_3_cyto PF07565.13 CDJ52639.1 - 8.5 6.1 12.9 13 5.5 12.5 1.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain MMU163 PF17119.5 CDJ52639.1 - 9.9 5.2 10.0 4 6.5 7.0 1.7 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis RNB PF00773.19 CDJ52640.1 - 8.2e-17 61.5 0.0 8.2e-17 61.5 0.0 4.5 4 2 1 5 5 5 1 RNB domain Spt20 PF12090.8 CDJ52641.1 - 0.0019 17.8 10.5 0.0025 17.5 10.5 1.2 1 0 0 1 1 1 1 Spt20 family YqzE PF14038.6 CDJ52641.1 - 0.25 11.4 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 YqzE-like protein SUIM_assoc PF16619.5 CDJ52641.1 - 5.1 7.2 28.0 4.9 7.3 14.2 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ETRAMP PF09716.10 CDJ52641.1 - 6.3 6.9 0.0 6.3 6.9 0.0 3.7 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF2722 PF10846.8 CDJ52642.1 - 0.00034 19.7 3.8 0.00034 19.7 3.8 4.0 4 0 0 4 4 3 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ52642.1 - 0.0016 18.5 81.0 0.21 11.5 27.5 3.1 3 0 0 3 3 3 3 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ52642.1 - 0.006 16.2 13.9 0.006 16.2 13.9 3.4 4 0 0 4 4 3 2 Spt20 family Tim54 PF11711.8 CDJ52642.1 - 0.063 12.1 13.1 0.065 12.0 6.0 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RNase_H2_suC PF08615.11 CDJ52642.1 - 0.098 12.8 5.1 13 6.0 0.1 3.3 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM176 PF14851.6 CDJ52642.1 - 0.098 12.3 9.0 0.55 9.9 1.1 3.2 3 0 0 3 3 3 0 FAM176 family DUF2828 PF11443.8 CDJ52642.1 - 0.15 10.1 9.9 0.28 9.2 4.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) SAPS PF04499.15 CDJ52642.1 - 0.23 10.2 5.6 0.17 10.7 0.5 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein TERB2 PF15101.6 CDJ52642.1 - 0.23 11.5 32.1 1.6 8.8 13.2 3.3 3 0 0 3 3 3 0 Telomere-associated protein TERB2 SLC12 PF03522.15 CDJ52642.1 - 0.24 10.4 12.5 0.24 10.4 4.7 2.3 2 0 0 2 2 2 0 Solute carrier family 12 TMEM223 PF14640.6 CDJ52642.1 - 0.38 10.9 3.0 10 6.3 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 223 DUF4834 PF16118.5 CDJ52642.1 - 0.41 11.6 32.7 0.22 12.5 5.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) CSG2 PF16965.5 CDJ52642.1 - 1.5 7.7 6.5 0.54 9.1 1.4 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator RLL PF10036.9 CDJ52642.1 - 1.7 8.4 30.3 0.12 12.2 4.0 3.3 3 0 0 3 3 3 0 RNA transcription, translation and transport factor protein Scs3p PF10261.9 CDJ52642.1 - 2.2 7.7 3.5 6.8 6.1 0.3 2.3 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM Apc15p PF05841.11 CDJ52642.1 - 3.1 8.6 34.8 0.32 11.8 7.5 4.5 4 0 0 4 4 4 0 Apc15p protein Stig1 PF04885.13 CDJ52642.1 - 3.7 8.0 17.1 0.23 12.0 4.9 3.1 3 0 0 3 3 3 0 Stigma-specific protein, Stig1 Connexin PF00029.19 CDJ52642.1 - 3.9 7.1 12.3 1.3 8.7 2.3 2.8 3 0 0 3 3 3 0 Connexin CAF1 PF04857.20 CDJ52642.1 - 4.4 6.4 10.3 6.6 5.8 0.0 2.5 2 1 0 3 3 3 0 CAF1 family ribonuclease Pet20 PF08692.10 CDJ52642.1 - 4.4 8.0 10.6 4.5 8.0 0.6 2.9 3 0 0 3 3 3 0 Mitochondrial protein Pet20 Otopetrin PF03189.13 CDJ52642.1 - 4.9 5.8 6.3 17 4.1 2.8 2.3 2 0 0 2 2 2 0 Otopetrin MMM1 PF10296.9 CDJ52642.1 - 7 5.6 9.6 0.99 8.4 0.3 2.6 3 0 0 3 3 3 0 Maintenance of mitochondrial morphology protein 1 Afi1 PF07792.12 CDJ52642.1 - 7.2 7.1 15.1 1.8 9.0 1.9 3.1 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2126 PF09899.9 CDJ52642.1 - 8.8 4.3 9.8 4.6 5.2 3.3 2.2 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) SpoIIP PF07454.11 CDJ52642.1 - 9.3 5.6 22.0 0.68 9.3 4.9 3.1 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) RHH_4 PF13467.6 CDJ52644.1 - 0.13 12.2 0.1 0.41 10.6 0.0 1.8 1 1 1 2 2 2 0 Ribbon-helix-helix domain SUIM_assoc PF16619.5 CDJ52645.1 - 0.013 15.5 0.5 0.013 15.5 0.5 17.4 12 6 2 14 14 14 0 Unstructured region C-term to UIM in Ataxin3 DUF755 PF05501.11 CDJ52647.1 - 0.17 12.2 18.6 0.23 11.8 18.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TFIIA PF03153.13 CDJ52647.1 - 3.9 7.4 21.1 4.5 7.2 21.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ52648.1 - 0.00042 20.4 9.5 0.00053 20.1 9.5 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ52648.1 - 0.014 15.4 23.6 0.017 15.1 23.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ52648.1 - 0.3 10.9 5.5 0.45 10.3 5.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ52648.1 - 0.37 10.8 2.6 0.41 10.6 2.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 CDJ52648.1 - 0.58 8.9 5.9 0.6 8.8 5.9 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ52648.1 - 1.2 10.2 7.7 2.1 9.3 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ52648.1 - 1.3 8.6 29.1 1.7 8.2 29.1 1.2 1 0 0 1 1 1 0 Spt20 family FUSC PF04632.12 CDJ52648.1 - 2.1 6.8 12.2 2.4 6.6 12.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CLN3 PF02487.17 CDJ52648.1 - 2.2 7.3 4.5 3.2 6.7 4.5 1.2 1 0 0 1 1 1 0 CLN3 protein UPF0560 PF10577.9 CDJ52648.1 - 4.5 5.7 15.0 5.5 5.4 15.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIA PF03153.13 CDJ52649.1 - 8e-05 22.8 50.0 0.00011 22.3 50.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ52649.1 - 8.1e-05 21.0 25.5 9e-05 20.8 25.5 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein RskA PF10099.9 CDJ52649.1 - 0.00086 19.6 13.6 2 8.7 13.7 2.6 1 1 0 1 1 1 1 Anti-sigma-K factor rskA IMUP PF15761.5 CDJ52649.1 - 0.0091 16.7 1.6 0.0091 16.7 1.6 2.3 2 0 0 2 2 1 1 Immortalisation up-regulated protein Nha1_C PF08619.10 CDJ52649.1 - 0.012 14.9 21.4 0.014 14.7 21.4 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF572 PF04502.13 CDJ52649.1 - 0.017 14.8 16.3 0.021 14.5 16.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Exonuc_VII_L PF02601.15 CDJ52649.1 - 0.019 14.5 22.8 0.02 14.5 22.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CCSAP PF15748.5 CDJ52649.1 - 0.023 14.9 28.9 0.038 14.2 28.9 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated K_channel_TID PF07941.11 CDJ52649.1 - 0.032 14.7 2.9 0.032 14.7 2.9 5.0 3 1 0 3 3 1 0 Potassium channel Kv1.4 tandem inactivation domain MRP-S27 PF10037.9 CDJ52649.1 - 0.036 12.9 27.3 0.039 12.8 27.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Presenilin PF01080.17 CDJ52649.1 - 0.051 12.3 28.0 0.064 12.0 28.0 1.2 1 0 0 1 1 1 0 Presenilin DUF853 PF05872.12 CDJ52649.1 - 0.065 11.8 12.1 0.078 11.6 12.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF5523 PF17661.1 CDJ52649.1 - 0.096 12.4 24.9 0.13 11.9 24.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Med15 PF09606.10 CDJ52649.1 - 0.1 11.3 50.1 0.1 11.3 50.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RIFIN PF02009.16 CDJ52649.1 - 0.63 9.9 17.2 0.98 9.2 17.2 1.2 1 0 0 1 1 1 0 Rifin Tti2 PF10521.9 CDJ52649.1 - 0.64 9.5 15.7 0.87 9.1 15.7 1.2 1 0 0 1 1 1 0 Tti2 family DUF966 PF06136.13 CDJ52649.1 - 0.69 9.6 20.1 0.82 9.3 20.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PAT1 PF09770.9 CDJ52649.1 - 0.7 8.1 42.2 0.83 7.8 42.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1387 PF07139.11 CDJ52649.1 - 0.84 9.3 22.8 1.4 8.6 22.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF2052 PF09747.9 CDJ52649.1 - 0.85 9.7 29.8 1.4 9.0 29.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SLC12 PF03522.15 CDJ52649.1 - 0.87 8.5 25.1 1 8.3 25.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 V_ATPase_I PF01496.19 CDJ52649.1 - 1.3 6.8 27.1 1.7 6.5 27.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_11 PF13086.6 CDJ52649.1 - 1.4 8.6 24.9 2.1 8.1 24.9 1.2 1 0 0 1 1 1 0 AAA domain Rrn6 PF10214.9 CDJ52649.1 - 1.6 7.2 27.4 1.8 6.9 27.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CobT PF06213.12 CDJ52649.1 - 1.9 7.8 36.7 3.1 7.1 36.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Caldesmon PF02029.15 CDJ52649.1 - 2.3 6.9 33.1 3.1 6.5 33.1 1.1 1 0 0 1 1 1 0 Caldesmon XRN_M PF17846.1 CDJ52649.1 - 2.4 7.0 16.6 3.1 6.6 16.6 1.3 1 0 0 1 1 1 0 Xrn1 helical domain PPP4R2 PF09184.11 CDJ52649.1 - 2.8 7.5 19.0 3.8 7.0 19.0 1.1 1 0 0 1 1 1 0 PPP4R2 FAM91_C PF14648.6 CDJ52649.1 - 3.1 6.5 15.0 4.1 6.1 15.0 1.3 1 0 0 1 1 1 0 FAM91 C-terminus GET2 PF08690.10 CDJ52649.1 - 4.3 6.9 30.7 5.3 6.6 30.7 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 SARG PF15385.6 CDJ52649.1 - 5 6.2 31.5 6.5 5.9 31.5 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein CDK5_activator PF03261.15 CDJ52649.1 - 5.1 6.5 20.1 6.5 6.2 20.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4746 PF15928.5 CDJ52649.1 - 5.5 6.3 22.2 9.3 5.6 22.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paramyxo_ncap PF00973.19 CDJ52649.1 - 5.8 5.7 19.4 7.5 5.4 19.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein BPL_N PF09825.9 CDJ52649.1 - 7.7 5.5 17.3 9.7 5.2 17.3 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Orf78 PF06024.12 CDJ52650.1 - 0.00052 20.3 1.3 0.00062 20.0 1.3 1.1 1 0 0 1 1 1 1 Orf78 (ac78) DUF5427 PF10310.9 CDJ52650.1 - 0.025 13.6 11.1 0.026 13.5 11.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Connexin PF00029.19 CDJ52650.1 - 0.035 13.9 4.8 0.037 13.8 4.8 1.1 1 0 0 1 1 1 0 Connexin TMEM144 PF07857.12 CDJ52650.1 - 0.051 12.5 0.2 0.06 12.3 0.2 1.0 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters EIIBC-GUT_N PF03612.14 CDJ52650.1 - 0.067 12.9 7.6 0.069 12.9 7.6 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peroxin-13_N PF04088.13 CDJ52650.1 - 0.081 13.2 5.5 0.088 13.1 5.5 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Folate_carrier PF01770.18 CDJ52650.1 - 0.086 11.6 6.9 0.09 11.5 6.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier RR_TM4-6 PF06459.12 CDJ52650.1 - 0.097 12.5 8.8 0.11 12.3 8.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Jak1_Phl PF17887.1 CDJ52650.1 - 0.1 12.6 9.3 0.12 12.4 9.3 1.0 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain PIP5K PF01504.18 CDJ52650.1 - 0.13 11.5 7.1 0.13 11.5 7.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF3464 PF11947.8 CDJ52650.1 - 0.14 11.9 9.4 0.14 11.9 9.4 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Renin_r PF07850.14 CDJ52650.1 - 0.14 12.8 2.3 0.16 12.6 2.3 1.1 1 0 0 1 1 1 0 Renin receptor-like protein Zip PF02535.22 CDJ52650.1 - 0.14 11.3 2.8 0.16 11.2 2.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 CDJ52650.1 - 0.16 10.9 3.1 0.14 11.1 3.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) HCO3_cotransp PF00955.21 CDJ52650.1 - 0.16 10.7 1.3 0.17 10.7 1.3 1.0 1 0 0 1 1 1 0 HCO3- transporter family Pex26 PF07163.12 CDJ52650.1 - 0.18 11.0 10.8 0.2 11.0 10.8 1.0 1 0 0 1 1 1 0 Pex26 protein Peptidase_S49_N PF08496.10 CDJ52650.1 - 0.19 11.8 7.3 0.21 11.7 7.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1764 PF08576.10 CDJ52650.1 - 0.2 12.5 7.7 0.24 12.3 7.7 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Pex14_N PF04695.13 CDJ52650.1 - 0.21 12.3 18.2 0.21 12.2 18.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.6 CDJ52650.1 - 0.25 11.0 4.1 0.28 10.9 4.1 1.1 1 0 0 1 1 1 0 FAM176 family Nucleoside_tran PF01733.18 CDJ52650.1 - 0.27 10.6 5.0 0.28 10.5 5.0 1.0 1 0 0 1 1 1 0 Nucleoside transporter DUF5385 PF17359.2 CDJ52650.1 - 0.28 10.7 10.6 0.32 10.5 10.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5385) RPA43_OB PF17875.1 CDJ52650.1 - 0.29 11.8 11.5 0.34 11.5 11.5 1.1 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Kei1 PF08552.11 CDJ52650.1 - 0.29 11.0 5.1 0.28 11.0 5.1 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 CCDC53 PF10152.9 CDJ52650.1 - 0.31 11.5 9.9 0.31 11.5 9.9 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex OATP PF03137.20 CDJ52650.1 - 0.33 9.2 5.0 0.32 9.2 5.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3043 PF11241.8 CDJ52650.1 - 0.51 10.3 8.8 0.58 10.2 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) CAF1 PF04857.20 CDJ52650.1 - 0.52 9.4 6.8 0.56 9.3 6.8 1.0 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF3408 PF11888.8 CDJ52650.1 - 0.53 10.4 11.9 0.56 10.3 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF4770 PF15994.5 CDJ52650.1 - 0.58 10.4 12.0 0.65 10.2 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FAM60A PF15396.6 CDJ52650.1 - 0.63 10.0 6.2 0.61 10.0 6.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DcuA_DcuB PF03605.14 CDJ52650.1 - 0.65 8.8 2.8 0.7 8.7 2.8 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter AIF_C PF14721.6 CDJ52650.1 - 0.78 10.1 8.1 0.9 9.9 8.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4407 PF14362.6 CDJ52650.1 - 0.86 8.9 12.8 0.95 8.8 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SARAF PF06682.12 CDJ52650.1 - 0.87 9.2 14.5 1.2 8.7 14.5 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CLN3 PF02487.17 CDJ52650.1 - 0.99 8.4 6.5 0.94 8.4 6.5 1.1 1 0 0 1 1 1 0 CLN3 protein EOS1 PF12326.8 CDJ52650.1 - 1 9.2 4.5 1.1 9.2 4.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein CSG2 PF16965.5 CDJ52650.1 - 1.1 8.1 4.1 1.1 8.2 4.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Neur_chan_memb PF02932.16 CDJ52650.1 - 1.1 9.2 6.0 1.1 9.3 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Corona_NS3b PF03053.14 CDJ52650.1 - 1.2 8.8 4.4 1.4 8.6 4.4 1.1 1 0 0 1 1 1 0 ORF3b coronavirus protein DDHD PF02862.17 CDJ52650.1 - 1.4 9.0 9.4 1.4 9.0 9.4 1.1 1 0 0 1 1 1 0 DDHD domain DUF4457 PF14652.6 CDJ52650.1 - 1.8 7.8 9.7 2 7.6 9.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) DUF4518 PF15008.6 CDJ52650.1 - 2 7.5 13.9 2.3 7.4 13.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) EMC3_TMCO1 PF01956.16 CDJ52650.1 - 2.5 7.8 12.4 2.5 7.8 12.4 1.0 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Presenilin PF01080.17 CDJ52650.1 - 3.5 6.3 14.4 3.7 6.2 14.4 1.1 1 0 0 1 1 1 0 Presenilin ABC2_membrane_2 PF12679.7 CDJ52650.1 - 3.7 6.7 7.0 4.2 6.6 7.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein FliP PF00813.20 CDJ52650.1 - 3.8 7.4 6.2 4.1 7.2 6.2 1.1 1 0 0 1 1 1 0 FliP family DUF4199 PF13858.6 CDJ52650.1 - 3.9 7.9 6.8 4.8 7.5 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) CrgA PF06781.12 CDJ52650.1 - 3.9 7.6 5.2 6.8 6.8 5.2 1.6 1 1 0 1 1 1 0 Cell division protein CrgA G0-G1_switch_2 PF15103.6 CDJ52650.1 - 4 7.9 8.9 4.6 7.7 8.9 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 Suf PF05843.14 CDJ52650.1 - 4.7 7.1 16.8 5 7.0 16.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CPSF100_C PF13299.6 CDJ52650.1 - 4.7 7.4 9.8 5.4 7.2 9.8 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CTU2 PF10288.9 CDJ52650.1 - 5.4 7.3 12.2 6.3 7.1 12.2 1.1 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 MTP18 PF10558.9 CDJ52650.1 - 6.4 6.7 6.1 6.7 6.6 6.1 1.1 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) PigN PF04987.14 CDJ52650.1 - 6.8 5.4 6.9 7.6 5.3 6.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) SseC PF04888.12 CDJ52650.1 - 7.2 6.1 18.2 7.5 6.0 18.2 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family MctB PF11382.8 CDJ52650.1 - 7.4 6.2 12.0 8.6 6.0 12.0 1.0 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB MscS_TM PF12794.7 CDJ52650.1 - 7.5 5.3 8.5 10 4.9 8.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 PepSY_TM PF03929.16 CDJ52650.1 - 8.1 6.0 7.9 8.6 5.9 7.9 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Band_3_cyto PF07565.13 CDJ52650.1 - 8.3 6.1 11.8 8.6 6.1 11.8 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SpoIIP PF07454.11 CDJ52650.1 - 8.3 5.8 15.6 8.5 5.7 15.6 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SF-assemblin PF06705.11 CDJ52651.1 - 0.0011 18.3 8.3 0.0011 18.3 8.3 1.5 1 1 0 1 1 1 1 SF-assemblin/beta giardin AphA_like PF14557.6 CDJ52651.1 - 0.074 12.8 5.2 0.089 12.5 5.2 1.1 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator FlgN PF05130.12 CDJ52651.1 - 0.4 11.2 18.5 0.6 10.6 18.5 1.2 1 0 0 1 1 1 0 FlgN protein Methyltransf_14 PF08484.11 CDJ52651.1 - 0.88 9.4 4.8 0.3 10.9 1.6 1.7 1 1 1 2 2 2 0 C-methyltransferase C-terminal domain betaPIX_CC PF16523.5 CDJ52651.1 - 1.6 8.6 14.0 1.9 8.4 0.5 2.9 1 1 1 2 2 2 0 betaPIX coiled coil DUF2722 PF10846.8 CDJ52652.1 - 0.00072 18.6 0.7 0.0014 17.7 6.4 7.0 2 2 5 7 7 7 2 Protein of unknown function (DUF2722) Coq4 PF05019.13 CDJ52653.1 - 3e-27 95.4 0.1 6.2e-22 78.0 0.1 2.2 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF1840 PF08895.11 CDJ52653.1 - 0.17 12.2 2.6 0.31 11.4 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) LRR_4 PF12799.7 CDJ52655.1 - 1.1e-16 60.6 10.6 8.5e-05 22.9 0.1 5.3 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ52655.1 - 2.4e-14 52.9 9.8 0.00011 21.9 0.1 5.2 4 1 1 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 CDJ52655.1 - 5.4e-07 29.3 1.3 0.00035 20.1 0.2 2.4 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CDJ52655.1 - 1.5e-05 24.6 5.2 0.87 9.8 0.0 6.6 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 CDJ52655.1 - 0.045 14.3 10.9 9.1 7.3 0.0 6.2 7 1 0 7 7 7 0 Leucine Rich Repeat MSC PF09402.10 CDJ52656.1 - 6.7e-12 45.5 1.8 1.2e-11 44.7 1.8 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain 3HCDH PF00725.22 CDJ52657.1 - 0.36 11.5 0.1 0.36 11.5 0.1 2.8 2 2 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain THRAP3_BCLAF1 PF15440.6 CDJ52657.1 - 0.95 8.4 22.7 1.1 8.2 22.7 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Caldesmon PF02029.15 CDJ52657.1 - 1.8 7.2 37.2 2.2 6.9 37.2 1.1 1 0 0 1 1 1 0 Caldesmon Presenilin PF01080.17 CDJ52658.1 - 0.075 11.8 42.5 0.078 11.7 42.5 1.0 1 0 0 1 1 1 0 Presenilin DUF2126 PF09899.9 CDJ52658.1 - 0.21 9.6 20.8 0.29 9.2 20.8 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RR_TM4-6 PF06459.12 CDJ52658.1 - 1 9.1 38.5 1.2 8.9 38.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.13 CDJ52658.1 - 1.9 8.3 32.5 2.4 7.9 32.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM60A PF15396.6 CDJ52658.1 - 2.2 8.2 31.0 2.7 8.0 31.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A NARP1 PF12569.8 CDJ52658.1 - 3.6 6.4 32.1 5.4 5.8 32.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PAT1 PF09770.9 CDJ52658.1 - 4.4 5.4 58.5 4.9 5.3 58.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Endostatin PF06482.11 CDJ52658.1 - 4.5 6.7 33.4 5.3 6.4 33.4 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin NPR3 PF03666.13 CDJ52658.1 - 5.3 5.7 36.8 6.1 5.5 36.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4045 PF13254.6 CDJ52658.1 - 6.2 6.4 32.4 6.9 6.2 32.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3295 PF11702.8 CDJ52658.1 - 7.5 5.8 33.5 8.7 5.6 33.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) SLC12 PF03522.15 CDJ52658.1 - 8.5 5.3 41.1 9 5.2 41.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF5427 PF10310.9 CDJ52658.1 - 8.7 5.2 37.1 10 4.9 37.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CD20 PF04103.15 CDJ52659.1 - 0.27 11.3 0.1 0.27 11.3 0.1 3.3 2 1 1 3 3 3 0 CD20-like family ETRAMP PF09716.10 CDJ52659.1 - 0.44 10.7 0.1 0.44 10.7 0.1 5.3 3 2 2 5 5 5 0 Malarial early transcribed membrane protein (ETRAMP) Cyt_bd_oxida_II PF02322.15 CDJ52659.1 - 6.6 6.0 15.6 0.3 10.4 8.6 1.9 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II Adaptin_N PF01602.20 CDJ52660.1 - 8.5e-49 166.5 0.8 3.9e-48 164.3 0.8 1.9 1 1 0 1 1 1 1 Adaptin N terminal region CCDC53 PF10152.9 CDJ52660.1 - 0.00013 22.4 1.7 0.37 11.2 0.1 2.2 2 0 0 2 2 2 2 Subunit CCDC53 of WASH complex HEAT_2 PF13646.6 CDJ52660.1 - 0.003 17.9 1.9 0.003 17.9 1.9 4.7 2 1 2 4 4 4 2 HEAT repeats RskA PF10099.9 CDJ52660.1 - 0.03 14.6 9.6 0.03 14.6 9.6 3.2 2 1 0 2 2 2 0 Anti-sigma-K factor rskA SLATT_1 PF18181.1 CDJ52660.1 - 0.16 11.9 10.5 0.28 11.1 1.9 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF3824 PF12868.7 CDJ52660.1 - 0.18 12.5 13.7 1.7 9.3 5.5 2.3 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF3391 PF11871.8 CDJ52660.1 - 0.37 11.3 14.7 1.5 9.3 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) OAD_gamma PF04277.13 CDJ52660.1 - 0.84 10.3 7.3 3.4 8.3 1.2 2.7 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain ADP_ribosyl_GH PF03747.14 CDJ52660.1 - 0.9 9.2 8.2 3.1 7.4 1.2 2.3 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase TFIIA PF03153.13 CDJ52660.1 - 0.96 9.4 33.5 1.1 9.2 14.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ52660.1 - 1.5 9.4 21.3 0.072 13.7 3.1 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein Coilin_N PF15862.5 CDJ52660.1 - 4.4 7.1 9.1 2.4 8.0 0.5 2.2 2 0 0 2 2 2 0 Coilin N-terminus Alpha_adaptinC2 PF02883.20 CDJ52661.1 - 2.9e-13 50.1 4.3 3.6e-12 46.6 0.0 3.1 2 1 0 2 2 2 1 Adaptin C-terminal domain Adaptin_N PF01602.20 CDJ52661.1 - 0.00018 20.2 0.1 0.0087 14.7 0.0 2.0 2 0 0 2 2 2 2 Adaptin N terminal region DUF4667 PF15700.5 CDJ52661.1 - 0.11 12.6 2.4 0.21 11.7 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) RLL PF10036.9 CDJ52661.1 - 1.8 8.3 9.3 0.16 11.8 4.4 1.7 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein Spt20 PF12090.8 CDJ52661.1 - 1.9 8.0 7.7 3.8 7.1 7.7 1.4 1 0 0 1 1 1 0 Spt20 family DUF1645 PF07816.11 CDJ52661.1 - 3.4 8.2 10.4 12 6.4 10.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) zf-C2HC_2 PF13913.6 CDJ52662.1 - 2.1e-08 33.9 9.1 0.00027 20.8 0.2 3.4 3 0 0 3 3 3 2 zinc-finger of a C2HC-type RskA PF10099.9 CDJ52662.1 - 3.7e-06 27.3 0.0 3.7e-06 27.3 0.0 3.2 1 1 1 2 2 1 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ52662.1 - 0.0064 15.5 9.6 0.0082 15.1 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) zf_C2HC_14 PF18574.1 CDJ52662.1 - 0.036 13.9 6.2 0.036 13.9 1.4 2.5 2 0 0 2 2 2 0 C2HC Zing finger domain DUF2318 PF10080.9 CDJ52662.1 - 0.076 13.1 4.4 6.3 7.0 0.0 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) DDHD PF02862.17 CDJ52662.1 - 0.086 13.0 2.9 0.11 12.7 2.9 1.2 1 0 0 1 1 1 0 DDHD domain zf-U11-48K PF05253.12 CDJ52662.1 - 0.13 12.2 0.5 0.13 12.2 0.5 2.3 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger Exonuc_VII_L PF02601.15 CDJ52662.1 - 0.21 11.1 10.6 0.29 10.7 10.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2197 PF09963.9 CDJ52662.1 - 0.48 10.7 5.6 0.12 12.6 1.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Actin_micro PF17003.5 CDJ52662.1 - 0.93 8.6 4.3 0.4 9.8 0.1 2.1 2 1 1 3 3 3 0 Putative actin-like family zf-C2H2_4 PF13894.6 CDJ52662.1 - 0.94 10.5 6.8 46 5.2 0.0 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger XAF1_C PF18608.1 CDJ52662.1 - 1.3 8.7 14.5 0.075 12.6 5.7 3.2 2 1 1 3 3 3 0 XIAP-associated factor 1 C-terminal domain Spt20 PF12090.8 CDJ52662.1 - 1.6 8.3 24.3 2.3 7.8 24.3 1.3 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 CDJ52662.1 - 2 6.6 17.1 2.4 6.3 17.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OmpH PF03938.14 CDJ52662.1 - 2.1 8.7 20.4 3.6 7.9 20.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Hid1 PF12722.7 CDJ52662.1 - 2.2 6.3 7.1 2.7 6.0 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.12 CDJ52662.1 - 2.4 7.0 11.5 3 6.7 11.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ52662.1 - 3.6 6.2 7.9 4.4 6.0 7.9 1.1 1 0 0 1 1 1 0 Presenilin PriA_CRR PF18319.1 CDJ52662.1 - 4.8 7.3 8.5 28 4.8 0.4 4.1 5 0 0 5 5 5 0 PriA DNA helicase Cys-rich region (CRR) domain Pkinase PF00069.25 CDJ52663.1 - 3.6e-11 42.9 0.0 1.2e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Spt20 PF12090.8 CDJ52663.1 - 0.00039 20.1 4.3 0.00039 20.1 4.3 3.5 3 0 0 3 3 3 2 Spt20 family Pex14_N PF04695.13 CDJ52663.1 - 0.21 12.2 0.2 0.21 12.2 0.2 6.5 4 2 3 7 7 7 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bromodomain PF00439.25 CDJ52664.1 - 2.3e-06 27.6 0.0 4.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain RskA PF10099.9 CDJ52664.1 - 0.013 15.8 10.6 0.013 15.8 10.6 13.2 2 2 7 9 9 9 0 Anti-sigma-K factor rskA LPG_synthase_TM PF03706.13 CDJ52665.1 - 0.012 15.1 2.3 0.02 14.4 2.3 1.3 1 1 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region RskA PF10099.9 CDJ52665.1 - 0.027 14.7 12.6 0.027 14.7 12.6 3.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF3295 PF11702.8 CDJ52665.1 - 0.48 9.7 36.3 0.76 9.1 36.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) RAP1 PF07218.11 CDJ52665.1 - 0.79 7.9 2.0 0.94 7.7 2.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CobT PF06213.12 CDJ52665.1 - 3.9 6.8 46.2 0.069 12.5 8.0 2.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VIR_N PF15912.5 CDJ52665.1 - 8.1 6.0 20.7 2.5 7.6 0.6 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal Folate_carrier PF01770.18 CDJ52665.1 - 9 4.9 18.6 0.046 12.5 1.2 2.3 2 0 0 2 2 2 0 Reduced folate carrier SUIM_assoc PF16619.5 CDJ52666.1 - 0.013 15.5 6.3 0.013 15.5 6.3 4.1 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Afi1 PF07792.12 CDJ52666.1 - 0.13 12.7 0.2 0.13 12.7 0.2 3.1 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SPX PF03105.19 CDJ52668.1 - 1e-11 45.4 37.9 1.2e-07 32.0 0.9 4.9 2 1 1 3 3 3 2 SPX domain Sporozoite_P67 PF05642.11 CDJ52668.1 - 4.6e-07 28.3 9.6 4.6e-07 28.3 9.6 4.7 4 2 0 4 4 4 2 Sporozoite P67 surface antigen Tir_receptor_N PF07490.11 CDJ52668.1 - 0.0017 18.3 0.3 0.0017 18.3 0.3 4.3 5 0 0 5 5 5 1 Translocated intimin receptor (Tir) N-terminus TPR_2 PF07719.17 CDJ52670.1 - 0.00018 21.3 13.0 0.00083 19.3 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ52670.1 - 0.00059 19.5 0.6 0.00059 19.5 0.6 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Trp_oprn_chp PF09534.10 CDJ52670.1 - 0.0033 17.3 15.7 0.0033 17.3 15.7 2.9 2 1 1 3 3 3 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TPR_10 PF13374.6 CDJ52670.1 - 0.024 14.5 0.0 0.024 14.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ52670.1 - 0.42 10.9 0.2 0.42 10.9 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat UCR_Fe-S_N PF10399.9 CDJ52670.1 - 0.94 8.9 0.0 0.94 8.9 0.0 4.0 3 1 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TPR_6 PF13174.6 CDJ52670.1 - 3.6 8.4 13.9 9.9 7.0 0.1 5.0 3 1 0 3 3 3 0 Tetratricopeptide repeat SLC12 PF03522.15 CDJ52670.1 - 9.9 5.1 46.8 0.45 9.5 14.8 2.2 2 0 0 2 2 2 0 Solute carrier family 12 Ricin_B_lectin PF00652.22 CDJ52671.1 - 0.1 12.9 0.3 0.52 10.6 0.1 2.2 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Sporozoite_P67 PF05642.11 CDJ52671.1 - 0.38 8.8 6.1 0.46 8.5 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HCV_NS5a_C PF12941.7 CDJ52671.1 - 0.78 9.5 9.5 1.4 8.7 9.5 1.3 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region CBF PF03914.17 CDJ52672.1 - 3.7e-14 53.1 5.0 4.1e-14 53.0 0.6 2.9 3 0 0 3 3 3 1 CBF/Mak21 family Host_attach PF10116.9 CDJ52672.1 - 6.5 7.3 12.2 18 5.9 1.3 2.6 2 0 0 2 2 2 0 Protein required for attachment to host cells Nop14 PF04147.12 CDJ52673.1 - 0.78 7.9 22.0 0.76 7.9 22.0 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 CDJ52673.1 - 2.6 6.4 20.5 3 6.2 20.5 1.0 1 0 0 1 1 1 0 Mpp10 protein Afi1 PF07792.12 CDJ52673.1 - 3.2 8.2 6.8 4 7.9 6.8 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF913 PF06025.12 CDJ52673.1 - 3.4 6.6 4.0 3.7 6.4 4.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DARPP-32 PF05395.12 CDJ52673.1 - 3.4 7.9 17.3 4.3 7.5 17.3 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 SDA1 PF05285.12 CDJ52673.1 - 3.9 6.8 22.0 4.6 6.6 22.0 1.1 1 0 0 1 1 1 0 SDA1 DUF5523 PF17661.1 CDJ52673.1 - 5.1 6.7 17.6 5.5 6.6 17.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) THOC2_N PF16134.5 CDJ52673.1 - 6.5 5.3 5.8 7.4 5.1 5.8 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus ORC_WH_C PF18137.1 CDJ52673.1 - 7.4 6.6 9.6 8.8 6.4 9.6 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF444 PF04285.12 CDJ52674.1 - 0.0099 15.0 1.2 0.014 14.5 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF444) MscS_TM PF12794.7 CDJ52674.1 - 0.66 8.8 1.2 0.98 8.2 1.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 PIEZO PF15917.5 CDJ52674.1 - 2 7.8 5.9 2.6 7.5 5.9 1.1 1 0 0 1 1 1 0 Piezo EF1_GNE PF00736.19 CDJ52675.1 - 1.5e-31 108.4 3.2 2.3e-31 107.8 3.2 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Abhydrolase_3 PF07859.13 CDJ52676.1 - 2.7e-32 112.4 0.0 2.7e-32 112.4 0.0 2.8 3 1 0 3 3 3 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDJ52676.1 - 1.3e-15 57.2 1.5 1.6e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase Spt20 PF12090.8 CDJ52677.1 - 0.021 14.5 13.1 0.036 13.7 13.1 1.4 1 0 0 1 1 1 0 Spt20 family DivIC PF04977.15 CDJ52677.1 - 0.065 13.0 8.3 0.12 12.1 8.3 1.3 1 0 0 1 1 1 0 Septum formation initiator Band_3_cyto PF07565.13 CDJ52677.1 - 0.28 11.0 2.0 0.51 10.1 2.0 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SR-25 PF10500.9 CDJ52680.1 - 2.9e-05 23.8 24.2 4.7e-05 23.1 24.2 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ52680.1 - 0.00087 19.0 30.3 0.0012 18.5 30.3 1.2 1 0 0 1 1 1 1 Spt20 family GREB1 PF15782.5 CDJ52680.1 - 0.0022 15.2 16.8 0.0025 15.1 16.8 1.1 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ52680.1 - 0.0041 16.7 21.6 0.0046 16.6 21.6 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Use1 PF09753.9 CDJ52680.1 - 0.013 15.2 17.1 0.017 14.8 17.1 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF5427 PF10310.9 CDJ52680.1 - 0.021 13.8 21.1 0.027 13.5 21.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4407 PF14362.6 CDJ52680.1 - 0.032 13.6 12.2 0.043 13.2 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 CDJ52680.1 - 0.036 12.6 16.1 0.044 12.4 16.1 1.1 1 0 0 1 1 1 0 Macoilin family Activator_LAG-3 PF11498.8 CDJ52680.1 - 0.043 12.8 35.6 0.059 12.3 35.6 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PAP1 PF08601.10 CDJ52680.1 - 0.044 13.5 17.0 0.06 13.1 17.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Tir_receptor_N PF07490.11 CDJ52680.1 - 0.048 13.5 2.4 0.075 12.9 2.4 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus DDHD PF02862.17 CDJ52680.1 - 0.13 12.4 13.4 0.22 11.7 13.4 1.4 1 0 0 1 1 1 0 DDHD domain CDK2AP PF09806.9 CDJ52680.1 - 0.13 12.3 15.2 0.2 11.7 15.2 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Rrn6 PF10214.9 CDJ52680.1 - 0.23 9.9 27.8 0.25 9.8 27.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PAT1 PF09770.9 CDJ52680.1 - 0.27 9.5 22.1 0.29 9.4 22.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4603 PF15376.6 CDJ52680.1 - 0.31 8.4 18.9 0.4 8.0 18.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) RR_TM4-6 PF06459.12 CDJ52680.1 - 0.39 10.5 15.9 0.48 10.2 15.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ52680.1 - 0.4 9.6 17.0 0.45 9.4 17.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4718 PF15842.5 CDJ52680.1 - 0.66 9.8 10.6 0.9 9.3 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Exonuc_VII_L PF02601.15 CDJ52680.1 - 0.86 9.1 17.7 1 8.9 17.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1682 PF07946.14 CDJ52680.1 - 0.88 8.7 22.3 1.1 8.4 22.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Neur_chan_memb PF02932.16 CDJ52680.1 - 0.88 9.6 10.5 1 9.4 10.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FapA PF03961.13 CDJ52680.1 - 1 7.9 14.3 1.2 7.7 14.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Plasmodium_Vir PF05795.11 CDJ52680.1 - 1.2 8.4 13.5 1.5 8.2 13.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein UPF0560 PF10577.9 CDJ52680.1 - 1.4 7.4 21.1 1.6 7.2 21.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1387 PF07139.11 CDJ52680.1 - 1.4 8.6 22.8 1.7 8.3 22.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF572 PF04502.13 CDJ52680.1 - 1.6 8.3 24.4 2 8.0 24.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) MAJIN PF15077.6 CDJ52680.1 - 1.7 8.4 15.2 2.2 8.0 15.2 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Peptidase_S64 PF08192.11 CDJ52680.1 - 2 6.8 21.3 2.4 6.5 21.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Band_3_cyto PF07565.13 CDJ52680.1 - 2.3 7.9 17.6 3 7.6 17.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Mgr1 PF08602.10 CDJ52680.1 - 2.4 6.9 10.7 3 6.6 10.7 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF4175 PF13779.6 CDJ52680.1 - 2.5 5.9 29.5 2.7 5.8 29.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mem_trans PF03547.18 CDJ52680.1 - 2.7 6.3 10.0 3.4 6.0 10.0 1.1 1 0 0 1 1 1 0 Membrane transport protein V_ATPase_I PF01496.19 CDJ52680.1 - 2.8 5.8 19.3 3.3 5.5 19.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Menin PF05053.13 CDJ52680.1 - 4.1 5.7 11.9 4.6 5.5 11.9 1.0 1 0 0 1 1 1 0 Menin Glyco_transf_41 PF13844.6 CDJ52680.1 - 4.4 5.6 7.9 5 5.4 7.9 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 41 SLC12 PF03522.15 CDJ52680.1 - 4.5 6.2 17.4 5.3 5.9 17.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 CDJ52680.1 - 4.6 5.3 21.5 5.3 5.1 21.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CLN3 PF02487.17 CDJ52680.1 - 4.8 6.1 10.1 5.8 5.8 10.1 1.2 1 0 0 1 1 1 0 CLN3 protein Paf1 PF03985.13 CDJ52680.1 - 5.6 5.9 31.5 6.9 5.6 31.3 1.3 1 1 0 1 1 1 0 Paf1 5_nucleotid PF05761.14 CDJ52680.1 - 6.4 5.6 13.5 7.6 5.3 13.5 1.1 1 0 0 1 1 1 0 5' nucleotidase family HCO3_cotransp PF00955.21 CDJ52680.1 - 6.5 5.5 5.3 7.5 5.3 5.3 1.1 1 0 0 1 1 1 0 HCO3- transporter family Suf PF05843.14 CDJ52680.1 - 6.7 6.6 19.0 7.3 6.5 19.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF755 PF05501.11 CDJ52680.1 - 6.9 7.0 43.1 14 6.0 43.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF755) UPF0524 PF15823.5 CDJ52680.1 - 7.3 5.9 11.9 11 5.3 11.9 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 Folate_carrier PF01770.18 CDJ52680.1 - 7.5 5.2 8.2 8.7 5.0 8.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier RP-C_C PF11800.8 CDJ52680.1 - 8.1 6.5 23.3 72 3.4 0.0 2.0 1 1 0 2 2 2 0 Replication protein C C-terminal region PTPlike_phytase PF14566.6 CDJ52680.1 - 8.1 6.5 12.1 12 5.9 12.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate ANAPC1 PF12859.7 CDJ52680.1 - 9.2 6.8 16.7 13 6.4 16.7 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 Miga PF10265.9 CDJ52680.1 - 9.8 5.0 18.3 13 4.6 18.3 1.1 1 0 0 1 1 1 0 Mitoguardin Spt20 PF12090.8 CDJ52681.1 - 0.21 11.2 11.3 0.25 10.9 11.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF4778 PF16008.5 CDJ52681.1 - 0.24 11.4 4.0 0.25 11.4 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) XRN_N PF03159.18 CDJ52681.1 - 0.77 9.1 3.3 0.8 9.1 3.3 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Roughex PF06020.11 CDJ52681.1 - 1.1 8.3 6.6 1.4 7.9 6.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Baculo_PP31 PF05311.11 CDJ52681.1 - 6.8 6.1 9.1 11 5.4 9.1 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) UPF0560 PF10577.9 CDJ52681.1 - 8.7 4.7 10.5 11 4.3 10.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Trp_oprn_chp PF09534.10 CDJ52683.1 - 0.079 12.8 6.7 3 7.6 7.2 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3357 PF11837.8 CDJ52683.1 - 0.24 11.9 5.5 0.35 11.4 2.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) RskA PF10099.9 CDJ52683.1 - 0.86 9.9 38.1 1.2 9.4 25.4 2.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA IHABP4_N PF16174.5 CDJ52683.1 - 1.4 9.5 31.4 0.93 10.1 22.6 2.5 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal SAPS PF04499.15 CDJ52683.1 - 2.8 6.6 13.9 11 4.6 14.5 1.7 1 1 1 2 2 2 0 SIT4 phosphatase-associated protein BAF1_ABF1 PF04684.13 CDJ52683.1 - 6.2 5.8 29.1 2 7.4 19.3 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.14 CDJ52683.1 - 6.7 6.6 34.9 0.94 9.4 1.9 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4175 PF13779.6 CDJ52683.1 - 7.5 4.3 42.4 0.34 8.8 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) TFIIA PF03153.13 CDJ52684.1 - 9.9e-05 22.5 35.1 0.00062 19.9 12.9 6.4 4 1 0 6 6 6 4 Transcription factor IIA, alpha/beta subunit HTH_Tnp_1 PF01527.20 CDJ52684.1 - 0.0016 18.7 0.1 0.014 15.7 0.1 2.7 1 0 0 1 1 1 1 Transposase Hemerythrin PF01814.23 CDJ52684.1 - 0.072 13.7 2.8 0.94 10.1 2.8 3.1 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Bromodomain PF00439.25 CDJ52685.1 - 2.6e-09 37.0 0.0 4.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain SR-25 PF10500.9 CDJ52685.1 - 0.0018 17.9 5.0 0.0018 17.9 5.0 10.7 10 1 1 11 11 11 1 Nuclear RNA-splicing-associated protein NAM-associated PF14303.6 CDJ52687.1 - 0.0051 17.5 0.0 0.0051 17.5 0.0 11.9 4 1 7 11 11 11 2 No apical meristem-associated C-terminal domain BPL_C PF02237.17 CDJ52687.1 - 0.018 14.9 0.5 0.054 13.4 0.5 1.8 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain CNDH2_M PF16869.5 CDJ52689.1 - 0.14 12.8 0.3 0.14 12.8 0.3 2.2 2 0 0 2 2 2 0 PF16858 SR-25 PF10500.9 CDJ52689.1 - 0.81 9.3 7.3 0.088 12.4 2.7 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 CDJ52691.1 - 1 6.4 36.6 1.2 6.2 36.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LMBR1 PF04791.16 CDJ52691.1 - 1.7 7.5 18.5 2.4 7.0 18.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Utp14 PF04615.13 CDJ52691.1 - 1.7 7.1 37.6 1.8 7.0 37.6 1.2 1 0 0 1 1 1 0 Utp14 protein DUF5523 PF17661.1 CDJ52691.1 - 2.6 7.6 37.3 4.2 7.0 37.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) LAP1C PF05609.12 CDJ52691.1 - 4 6.4 41.1 4.4 6.3 41.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF572 PF04502.13 CDJ52691.1 - 5.3 6.6 32.6 7.1 6.2 32.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Caldesmon PF02029.15 CDJ52691.1 - 6.2 5.5 39.1 7.5 5.2 39.1 1.1 1 0 0 1 1 1 0 Caldesmon Peptidase_S64 PF08192.11 CDJ52691.1 - 6.9 5.0 31.5 7.7 4.9 31.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 RskA PF10099.9 CDJ52692.1 - 0.013 15.8 12.7 0.013 15.8 12.7 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ52692.1 - 0.076 12.6 3.5 0.1 12.2 3.5 1.2 1 0 0 1 1 1 0 Spt20 family DUF4179 PF13786.6 CDJ52692.1 - 0.077 13.5 2.1 0.15 12.5 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF3138 PF11336.8 CDJ52692.1 - 0.12 10.9 10.6 0.2 10.2 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Med3 PF11593.8 CDJ52692.1 - 0.13 11.5 9.8 0.18 10.9 9.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HECT PF00632.25 CDJ52693.1 - 5.4e-09 36.0 0.0 3.9e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) PAP1 PF08601.10 CDJ52693.1 - 0.077 12.7 0.0 0.077 12.7 0.0 10.3 6 2 4 10 10 10 0 Transcription factor PAP1 ESM4 PF15952.5 CDJ52694.1 - 0.11 13.0 0.3 0.11 13.0 0.3 2.2 2 0 0 2 2 2 0 Enhancer of split M4 family Folate_carrier PF01770.18 CDJ52694.1 - 0.64 8.7 7.9 1.2 7.8 7.9 1.4 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.20 CDJ52694.1 - 1.1 7.5 9.2 0.27 9.5 4.6 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1645 PF07816.11 CDJ52694.1 - 1.3 9.6 11.0 3.4 8.2 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) FapA PF03961.13 CDJ52694.1 - 7.2 5.1 17.2 12 4.3 12.5 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A GILT PF03227.16 CDJ52695.1 - 5.2e-20 71.7 0.1 5.2e-20 71.7 0.1 1.9 2 1 0 2 2 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) eIF-3_zeta PF05091.12 CDJ52695.1 - 0.0035 16.4 11.9 0.0044 16.1 11.9 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CDJ52695.1 - 0.0046 15.3 21.3 0.0049 15.2 21.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Tim54 PF11711.8 CDJ52695.1 - 0.024 13.4 9.4 0.029 13.1 9.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.13 CDJ52695.1 - 0.12 12.3 40.6 0.21 11.5 40.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF913 PF06025.12 CDJ52695.1 - 0.12 11.3 8.8 0.15 11.0 8.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GET2 PF08690.10 CDJ52695.1 - 0.18 11.5 13.9 0.22 11.1 13.9 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF740 PF05340.12 CDJ52695.1 - 0.23 10.2 15.4 0.3 9.8 15.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) SID-1_RNA_chan PF13965.6 CDJ52695.1 - 0.24 9.8 4.0 0.27 9.6 4.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ52695.1 - 0.42 10.6 12.0 0.57 10.2 12.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4820 PF16091.5 CDJ52695.1 - 0.82 9.0 12.7 1.4 8.3 12.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) MMR1 PF08505.10 CDJ52695.1 - 1.2 9.3 16.8 2 8.6 16.8 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Lin-8 PF03353.15 CDJ52695.1 - 1.4 8.4 21.2 2 7.9 21.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ALMT PF11744.8 CDJ52695.1 - 1.8 7.3 15.3 2.3 6.9 15.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Band_3_cyto PF07565.13 CDJ52695.1 - 1.9 8.2 16.1 3.2 7.5 16.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Hid1 PF12722.7 CDJ52695.1 - 2.5 6.1 15.3 3 5.8 15.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CDJ52695.1 - 3.2 6.4 23.2 5.3 5.7 23.2 1.3 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ52695.1 - 3.7 6.4 19.9 6.1 5.8 19.9 1.3 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 CDJ52695.1 - 3.9 5.7 18.5 5.7 5.1 18.5 1.2 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 CDJ52695.1 - 4.6 5.9 16.8 7.5 5.2 16.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Gti1_Pac2 PF09729.9 CDJ52695.1 - 7.1 6.7 16.1 14 5.7 16.1 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Membralin PF09746.9 CDJ52695.1 - 9 5.2 11.7 12 4.8 11.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein Serinc PF03348.15 CDJ52695.1 - 9.5 5.0 8.6 15 4.4 8.6 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) SpoIIP PF07454.11 CDJ52695.1 - 9.6 5.6 19.4 18 4.7 19.4 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pex14_N PF04695.13 CDJ52696.1 - 0.013 16.2 1.7 0.02 15.6 1.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ52696.1 - 0.035 14.1 7.1 0.038 14.0 7.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ52696.1 - 0.042 13.8 0.7 0.053 13.5 0.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EIF4E-T PF10477.9 CDJ52696.1 - 0.092 11.6 7.1 0.11 11.2 7.1 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Spore_YhcN_YlaJ PF09580.10 CDJ52700.1 - 0.0026 17.8 1.5 0.01 15.9 0.3 2.2 2 0 0 2 2 2 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) MAM33 PF02330.16 CDJ52701.1 - 0.25 11.2 0.0 0.25 11.2 0.0 5.7 4 1 2 6 6 6 0 Mitochondrial glycoprotein AUX_IAA PF02309.16 CDJ52702.1 - 3.6 7.4 18.0 4.6 7.0 18.0 1.1 1 0 0 1 1 1 0 AUX/IAA family Presenilin PF01080.17 CDJ52702.1 - 5.5 5.6 32.0 6.6 5.4 32.0 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ52702.1 - 6.9 6.6 22.4 8.9 6.2 22.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 CDJ52702.1 - 7.2 5.5 26.8 8 5.4 26.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4614 PF15391.6 CDJ52703.1 - 0.55 10.2 8.0 0.82 9.6 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 CDJ52703.1 - 5.8 5.6 7.7 7.2 5.3 7.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RSRP PF17069.5 CDJ52703.1 - 10 5.6 26.8 15 5.1 26.8 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 HipN PF18253.1 CDJ52705.1 - 1.7e-15 56.4 0.1 3.5e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain TPR_16 PF13432.6 CDJ52705.1 - 4.7e-05 24.0 3.7 4.7e-05 24.0 3.7 2.0 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ52705.1 - 6.9e-05 22.5 11.9 0.00029 20.5 1.4 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat STI1 PF17830.1 CDJ52705.1 - 7.4e-05 22.6 0.1 0.00018 21.4 0.1 1.7 1 0 0 1 1 1 1 STI1 domain TPR_2 PF07719.17 CDJ52705.1 - 0.00037 20.4 13.2 0.001 19.0 0.7 3.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ52705.1 - 0.0028 17.9 2.6 0.098 13.0 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Rrn6 PF10214.9 CDJ52705.1 - 0.014 13.9 0.6 0.016 13.7 0.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TPR_19 PF14559.6 CDJ52705.1 - 0.022 15.2 2.1 0.022 15.2 2.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ52705.1 - 0.11 12.2 1.6 0.26 11.0 0.2 2.2 1 1 1 2 2 2 0 TPR repeat TPR_8 PF13181.6 CDJ52705.1 - 0.67 10.3 11.7 0.59 10.5 0.5 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat PTPRCAP PF15713.5 CDJ52705.1 - 1.2 9.5 19.8 0.13 12.5 6.4 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated TFIIA PF03153.13 CDJ52706.1 - 0.41 10.6 22.1 0.52 10.2 22.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ52706.1 - 0.51 9.3 6.5 0.62 9.0 6.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ52706.1 - 3.1 6.5 7.7 3.8 6.2 7.7 1.2 1 0 0 1 1 1 0 Presenilin Fumerase PF05681.14 CDJ52707.1 - 1.1e-31 110.3 0.2 1.2e-28 100.4 0.0 2.5 2 1 1 3 3 3 2 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 CDJ52707.1 - 9.2e-21 74.1 1.6 9.8e-21 74.0 0.0 1.7 2 0 0 2 2 2 1 Fumarase C-terminus RskA PF10099.9 CDJ52707.1 - 0.04 14.2 21.1 13 6.0 21.1 2.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Folate_carrier PF01770.18 CDJ52707.1 - 0.098 11.4 1.1 0.15 10.8 1.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier SelP_N PF04592.14 CDJ52707.1 - 0.13 11.7 20.3 0.21 11.0 20.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CPSF73-100_C PF11718.8 CDJ52707.1 - 0.56 9.7 5.1 0.85 9.1 5.1 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lin-8 PF03353.15 CDJ52708.1 - 0.0012 18.5 26.6 0.0012 18.5 26.6 2.1 2 0 0 2 2 2 1 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ52708.1 - 0.0058 16.6 24.5 0.0089 16.0 24.5 1.3 1 0 0 1 1 1 1 SPX domain Arm PF00514.23 CDJ52708.1 - 0.026 14.5 0.2 1.5 8.9 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat SSP160 PF06933.11 CDJ52708.1 - 0.047 11.9 5.3 0.062 11.5 5.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 EB1_binding PF05937.11 CDJ52708.1 - 0.067 13.8 11.4 0.15 12.7 11.4 1.6 1 0 0 1 1 1 0 EB-1 Binding Domain RAP1 PF07218.11 CDJ52708.1 - 0.22 9.8 4.2 0.27 9.5 4.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NST1 PF13945.6 CDJ52708.1 - 0.55 10.3 43.8 0.09 12.9 30.0 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Cwf_Cwc_15 PF04889.12 CDJ52708.1 - 2.1 8.0 24.3 0.89 9.2 16.2 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Plasmodium_Vir PF05795.11 CDJ52708.1 - 2.6 7.4 22.4 3.7 6.9 15.1 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SARAF PF06682.12 CDJ52708.1 - 8.5 5.9 37.9 0.51 9.9 26.3 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Spore_III_AF PF09581.10 CDJ52708.1 - 8.8 6.3 25.1 0.15 12.1 2.8 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Utp14 PF04615.13 CDJ52708.1 - 9.1 4.7 30.8 13 4.2 30.8 1.1 1 0 0 1 1 1 0 Utp14 protein DctQ PF04290.12 CDJ52711.1 - 0.0078 16.1 4.4 1.7 8.5 0.1 2.8 3 0 0 3 3 3 2 Tripartite ATP-independent periplasmic transporters, DctQ component DUF4064 PF13273.6 CDJ52711.1 - 0.012 15.9 1.0 0.5 10.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF2079 PF09852.9 CDJ52711.1 - 0.014 14.2 0.8 0.16 10.8 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) YajC PF02699.15 CDJ52711.1 - 0.027 14.4 2.1 0.027 14.4 2.1 4.4 3 2 1 4 4 2 0 Preprotein translocase subunit SIT PF15330.6 CDJ52711.1 - 0.042 14.3 0.1 0.042 14.3 0.1 3.3 3 1 1 4 4 3 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3742 PF12553.8 CDJ52711.1 - 0.045 13.9 0.8 0.28 11.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) DUF2140 PF09911.9 CDJ52711.1 - 0.055 13.0 0.0 0.055 13.0 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) Trp_oprn_chp PF09534.10 CDJ52711.1 - 0.081 12.7 43.2 0.029 14.2 4.2 3.5 3 1 1 4 4 4 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Peptidase_M50 PF02163.22 CDJ52711.1 - 0.11 11.8 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M50 EphA2_TM PF14575.6 CDJ52711.1 - 0.3 12.0 0.0 0.3 12.0 0.0 3.2 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.6 CDJ52711.1 - 0.46 10.1 1.8 2.2 7.9 0.0 2.5 3 0 0 3 3 3 0 FAM176 family Conotoxin PF02950.17 CDJ52711.1 - 1 10.5 0.0 1 10.5 0.0 4.4 4 1 0 4 4 4 0 Conotoxin DUF4834 PF16118.5 CDJ52711.1 - 1.4 9.9 0.0 1.4 9.9 0.0 3.7 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) SARAF PF06682.12 CDJ52712.1 - 3.7 7.1 0.0 1.2 8.7 1.9 7.6 5 4 3 8 8 8 0 SOCE-associated regulatory factor of calcium homoeostasis Presenilin PF01080.17 CDJ52713.1 - 2.7 6.7 27.1 2.9 6.5 27.1 1.0 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ52713.1 - 4.9 5.0 24.7 5.3 4.8 24.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family O-antigen_lig PF13425.6 CDJ52713.1 - 5.5 5.7 15.9 6.1 5.5 15.9 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RR_TM4-6 PF06459.12 CDJ52713.1 - 7.2 6.3 25.7 7.5 6.3 25.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC53 PF10152.9 CDJ52713.1 - 7.2 7.0 22.6 9.6 6.6 22.6 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CSG2 PF16965.5 CDJ52713.1 - 7.4 5.4 11.2 8.8 5.2 11.2 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Paf1 PF03985.13 CDJ52713.1 - 8.1 5.3 25.3 9.8 5.0 25.3 1.1 1 0 0 1 1 1 0 Paf1 Pal1 PF08316.11 CDJ52713.1 - 9.6 7.0 12.3 13 6.5 12.3 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein Presenilin PF01080.17 CDJ52714.1 - 0.64 8.7 24.1 0.71 8.6 24.1 1.0 1 0 0 1 1 1 0 Presenilin Afi1 PF07792.12 CDJ52714.1 - 0.87 10.1 18.9 5.3 7.5 18.9 1.9 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MAJIN PF15077.6 CDJ52714.1 - 1.1 9.0 14.0 1.6 8.5 14.0 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein MDM10 PF12519.8 CDJ52714.1 - 3.3 6.5 14.4 3.9 6.2 14.4 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4569 PF15133.6 CDJ52714.1 - 8.2 6.0 22.0 9.2 5.9 22.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF1764 PF08576.10 CDJ52715.1 - 8.7 7.3 15.3 14 6.7 15.3 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) N2227 PF07942.12 CDJ52717.1 - 6.6e-32 110.8 0.2 1.2e-31 109.9 0.0 1.5 1 1 1 2 2 2 1 N2227-like protein Methyltransf_11 PF08241.12 CDJ52717.1 - 0.0063 17.1 0.2 0.048 14.3 0.0 2.3 2 1 1 3 3 3 1 Methyltransferase domain TFIIA PF03153.13 CDJ52717.1 - 0.048 13.7 24.3 0.053 13.5 24.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ52717.1 - 0.099 12.8 5.9 0.13 12.4 5.9 1.1 1 0 0 1 1 1 0 DDHD domain Exonuc_VII_L PF02601.15 CDJ52717.1 - 0.11 12.0 12.1 0.14 11.7 12.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Methyltransf_23 PF13489.6 CDJ52717.1 - 0.17 11.7 0.0 0.17 11.7 0.0 2.3 1 1 1 2 2 1 0 Methyltransferase domain Het-C PF07217.11 CDJ52717.1 - 0.21 10.1 5.6 0.25 9.9 5.6 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Presenilin PF01080.17 CDJ52717.1 - 1.6 7.4 5.6 2 7.1 5.6 1.1 1 0 0 1 1 1 0 Presenilin Rpp20 PF12328.8 CDJ52717.1 - 1.6 8.7 7.7 2.6 8.0 7.7 1.3 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF4407 PF14362.6 CDJ52717.1 - 2.6 7.3 10.6 4 6.7 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Eaf7 PF07904.13 CDJ52717.1 - 2.6 8.5 8.2 0.7 10.3 0.2 2.1 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 Peroxin-13_N PF04088.13 CDJ52717.1 - 4.9 7.4 7.9 8.8 6.6 7.8 1.4 1 1 0 1 1 1 0 Peroxin 13, N-terminal region DUF3138 PF11336.8 CDJ52718.1 - 6.7 5.2 9.2 7.3 5.1 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_L28 PF00830.19 CDJ52719.1 - 3.4e-15 56.0 2.0 3.4e-15 56.0 2.0 2.2 2 0 0 2 2 2 1 Ribosomal L28 family Peroxin-13_N PF04088.13 CDJ52720.1 - 0.0075 16.5 3.2 0.0078 16.5 3.2 1.1 1 0 0 1 1 1 1 Peroxin 13, N-terminal region RNA_pol_Rbc25 PF08292.12 CDJ52720.1 - 0.019 15.2 4.2 0.024 14.9 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Zip PF02535.22 CDJ52720.1 - 0.034 13.4 11.2 0.039 13.2 11.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter PigN PF04987.14 CDJ52720.1 - 0.039 12.8 6.8 0.042 12.7 6.8 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) EIIBC-GUT_N PF03612.14 CDJ52720.1 - 0.045 13.5 6.8 0.048 13.4 6.8 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2370 PF10176.9 CDJ52720.1 - 0.046 13.4 3.2 0.045 13.4 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Presenilin PF01080.17 CDJ52720.1 - 0.053 12.3 9.1 0.056 12.2 9.1 1.0 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 CDJ52720.1 - 0.066 13.0 6.5 0.071 12.9 6.5 1.0 1 0 0 1 1 1 0 Connexin CCDC53 PF10152.9 CDJ52720.1 - 0.068 13.6 7.2 0.074 13.5 7.2 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Orf78 PF06024.12 CDJ52720.1 - 0.075 13.3 3.5 0.099 13.0 3.5 1.2 1 0 0 1 1 1 0 Orf78 (ac78) CbtA PF09490.10 CDJ52720.1 - 0.084 12.6 6.8 0.094 12.5 6.8 1.0 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Pex14_N PF04695.13 CDJ52720.1 - 0.094 13.4 17.5 0.1 13.2 17.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ORC_WH_C PF18137.1 CDJ52720.1 - 0.13 12.4 8.9 0.13 12.3 8.9 1.0 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal SLC12 PF03522.15 CDJ52720.1 - 0.15 11.0 7.5 0.15 11.1 7.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FAM176 PF14851.6 CDJ52720.1 - 0.16 11.7 3.8 0.16 11.6 3.8 1.1 1 0 0 1 1 1 0 FAM176 family CPSF100_C PF13299.6 CDJ52720.1 - 0.18 12.0 4.9 0.19 11.9 4.9 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Kei1 PF08552.11 CDJ52720.1 - 0.18 11.7 3.7 0.2 11.5 3.7 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Tim54 PF11711.8 CDJ52720.1 - 0.3 9.8 6.9 0.34 9.7 6.9 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MDM10 PF12519.8 CDJ52720.1 - 0.37 9.6 7.1 0.36 9.6 7.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF3464 PF11947.8 CDJ52720.1 - 0.39 10.5 8.5 0.45 10.3 8.5 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF5336 PF17270.2 CDJ52720.1 - 0.43 10.2 16.0 0.74 9.4 16.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5336) AIF_C PF14721.6 CDJ52720.1 - 0.44 10.9 6.7 0.47 10.8 6.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term GET2 PF08690.10 CDJ52720.1 - 0.51 10.0 10.5 0.59 9.8 10.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 RIC3 PF15361.6 CDJ52720.1 - 0.52 10.7 10.1 0.55 10.6 10.1 1.0 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4770 PF15994.5 CDJ52720.1 - 0.54 10.5 12.8 0.67 10.2 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF868 PF05910.12 CDJ52720.1 - 0.55 9.8 6.8 0.57 9.8 6.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) CD20 PF04103.15 CDJ52720.1 - 0.57 10.2 1.9 0.68 10.0 1.9 1.1 1 0 0 1 1 1 0 CD20-like family EPL1 PF10513.9 CDJ52720.1 - 0.61 10.5 12.2 0.67 10.3 12.2 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like RR_TM4-6 PF06459.12 CDJ52720.1 - 0.61 9.9 9.4 0.69 9.7 9.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PIP5K PF01504.18 CDJ52720.1 - 0.64 9.2 9.0 0.73 9.0 9.0 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DcuA_DcuB PF03605.14 CDJ52720.1 - 0.74 8.6 2.3 0.81 8.5 2.3 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF2464 PF10240.9 CDJ52720.1 - 0.81 9.2 6.4 0.85 9.1 6.4 1.0 1 0 0 1 1 1 0 Multivesicular body subunit 12 Neur_chan_memb PF02932.16 CDJ52720.1 - 1 9.4 8.1 1.2 9.1 8.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OATP PF03137.20 CDJ52720.1 - 1 7.5 6.6 1.1 7.4 6.6 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Gti1_Pac2 PF09729.9 CDJ52720.1 - 1.2 9.2 9.2 1.4 9.0 9.2 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family ArsP_2 PF11449.8 CDJ52720.1 - 1.3 8.2 2.9 1.4 8.1 2.9 1.0 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter Folate_carrier PF01770.18 CDJ52720.1 - 1.3 7.7 6.2 1.4 7.6 6.2 1.0 1 0 0 1 1 1 0 Reduced folate carrier Peptidase_S49_N PF08496.10 CDJ52720.1 - 1.3 9.0 7.8 1.4 9.0 7.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sec62 PF03839.16 CDJ52720.1 - 1.7 8.1 7.2 2 7.9 7.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Suf PF05843.14 CDJ52720.1 - 1.7 8.5 17.4 2 8.3 17.4 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM60A PF15396.6 CDJ52720.1 - 2 8.4 8.6 2.3 8.2 8.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A TMEM51 PF15345.6 CDJ52720.1 - 2 8.2 11.2 2.4 7.9 11.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 CSG2 PF16965.5 CDJ52720.1 - 2.1 7.2 5.0 2.1 7.2 5.0 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator MENTAL PF10457.9 CDJ52720.1 - 2.1 8.1 5.3 2.3 8.0 5.3 1.1 1 0 0 1 1 1 0 Cholesterol-capturing domain RBM39linker PF15519.6 CDJ52720.1 - 2.1 9.5 9.1 2.7 9.1 9.1 1.1 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein MDM31_MDM32 PF08118.11 CDJ52720.1 - 2.1 6.9 8.9 2.3 6.8 8.9 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins RICTOR_N PF14664.6 CDJ52720.1 - 2.3 7.1 4.8 2.4 7.1 4.8 1.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Lin-8 PF03353.15 CDJ52720.1 - 2.4 7.6 15.4 2.4 7.6 15.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Baculo_PP31 PF05311.11 CDJ52720.1 - 3 7.2 10.1 3 7.3 10.1 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FliP PF00813.20 CDJ52720.1 - 3.2 7.6 6.5 3.5 7.5 6.5 1.0 1 0 0 1 1 1 0 FliP family TFIIA PF03153.13 CDJ52720.1 - 3.5 7.5 32.4 3.3 7.6 32.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLN3 PF02487.17 CDJ52720.1 - 3.6 6.5 9.2 3.7 6.5 9.2 1.1 1 0 0 1 1 1 0 CLN3 protein DUF2828 PF11443.8 CDJ52720.1 - 3.6 5.5 10.8 4.1 5.4 10.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MscS_TM PF12794.7 CDJ52720.1 - 4 6.2 7.8 4.4 6.1 7.8 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 EOS1 PF12326.8 CDJ52720.1 - 4.3 7.2 6.2 4.8 7.1 6.2 1.1 1 0 0 1 1 1 0 N-glycosylation protein Serinc PF03348.15 CDJ52720.1 - 4.8 6.0 6.6 5.3 5.9 6.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Nucleoside_tran PF01733.18 CDJ52720.1 - 5.1 6.4 4.9 5.2 6.4 4.9 1.0 1 0 0 1 1 1 0 Nucleoside transporter DUF3112 PF11309.8 CDJ52720.1 - 5.2 6.5 5.0 6.2 6.2 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) AF-4 PF05110.13 CDJ52720.1 - 5.4 5.0 17.9 5.6 4.9 17.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ALMT PF11744.8 CDJ52720.1 - 5.5 5.7 9.4 6.1 5.6 9.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Ctr PF04145.15 CDJ52720.1 - 7.2 7.2 7.8 8.2 7.0 7.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Band_3_cyto PF07565.13 CDJ52720.1 - 9.5 5.9 13.9 11 5.8 13.9 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pkinase_Tyr PF07714.17 CDJ52721.1 - 7.7e-30 104.0 0.0 2.8e-17 62.9 0.0 3.7 3 1 1 4 4 4 2 Protein tyrosine kinase Pkinase PF00069.25 CDJ52721.1 - 2.5e-23 82.8 0.0 1.6e-13 50.6 0.0 3.9 3 2 2 5 5 4 2 Protein kinase domain SAM_1 PF00536.30 CDJ52721.1 - 1.2e-05 25.7 0.5 2.2e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GEMIN8 PF15348.6 CDJ52721.1 - 1.8e-05 25.2 4.3 1.8e-05 25.2 4.3 3.0 2 2 0 2 2 2 1 Gemini of Cajal bodies-associated protein 8 TFIIA PF03153.13 CDJ52721.1 - 0.00014 22.0 61.9 0.0075 16.3 23.7 3.2 3 0 0 3 3 3 3 Transcription factor IIA, alpha/beta subunit SAM_2 PF07647.17 CDJ52721.1 - 0.00032 20.7 0.4 0.00067 19.7 0.4 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Med15 PF09606.10 CDJ52721.1 - 0.0016 17.3 50.3 0.027 13.2 31.6 2.4 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CDJ52721.1 - 0.07 12.1 0.1 0.07 12.1 0.1 4.8 4 1 1 5 5 3 0 Protein of unknown function (DUF2722) DUF4179 PF13786.6 CDJ52721.1 - 0.071 13.6 0.9 16 6.1 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) MORN PF02493.20 CDJ52721.1 - 0.095 12.6 7.8 0.26 11.3 2.0 2.6 2 0 0 2 2 2 0 MORN repeat Apt1 PF10351.9 CDJ52721.1 - 1.4 7.7 25.9 2 7.2 8.6 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Mem_trans PF03547.18 CDJ52721.1 - 3.9 5.8 6.1 6 5.1 1.1 2.2 2 0 0 2 2 2 0 Membrane transport protein Myc_N PF01056.18 CDJ52721.1 - 4.1 7.2 29.3 1.1 9.0 15.8 2.5 2 0 0 2 2 2 0 Myc amino-terminal region PepSY_TM PF03929.16 CDJ52721.1 - 6.7 6.3 10.8 9.7 5.8 1.9 3.1 3 0 0 3 3 3 0 PepSY-associated TM region DUF2722 PF10846.8 CDJ52723.1 - 0.0063 15.5 9.9 0.0063 15.5 9.9 6.9 5 1 1 6 6 6 3 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ52724.1 - 7.4e-09 36.2 14.0 1.7e-05 25.2 11.3 21.0 8 7 6 16 16 16 4 Anti-sigma-K factor rskA GREB1 PF15782.5 CDJ52725.1 - 8.1 3.4 64.8 11 2.9 64.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 CDJ52726.1 - 0.14 11.3 9.1 0.11 11.6 6.5 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Borrelia_P83 PF05262.11 CDJ52726.1 - 0.39 9.2 18.4 0.67 8.4 18.4 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein PA26 PF04636.13 CDJ52726.1 - 0.6 9.0 13.7 0.072 12.0 9.3 1.7 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) LMBR1 PF04791.16 CDJ52726.1 - 1.3 7.9 6.6 1.6 7.5 6.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CRT10 PF08728.10 CDJ52726.1 - 2.1 6.4 16.6 0.6 8.2 11.5 1.9 2 0 0 2 2 2 0 CRT10 SID-1_RNA_chan PF13965.6 CDJ52726.1 - 2.3 6.5 8.0 0.19 10.1 3.6 1.4 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 SPX PF03105.19 CDJ52726.1 - 3.3 7.5 26.5 2.1 8.2 16.2 2.2 2 0 0 2 2 2 0 SPX domain MMR1 PF08505.10 CDJ52726.1 - 5.2 7.3 34.1 0.041 14.2 20.8 2.6 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein Lin-8 PF03353.15 CDJ52726.1 - 9.5 5.7 35.8 3.8 7.0 28.6 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Cpn60_TCP1 PF00118.24 CDJ52727.1 - 4.2e-134 447.9 9.2 4.8e-134 447.7 9.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TB2_DP1_HVA22 PF03134.19 CDJ52728.1 - 1.8e-14 53.4 2.9 2.7e-14 52.8 2.9 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family SURF1 PF02104.15 CDJ52729.1 - 5.2e-25 88.7 4.7 3.3e-16 60.0 1.4 3.0 2 1 0 2 2 2 2 SURF1 family Adaptin_binding PF10199.9 CDJ52729.1 - 0.023 15.3 0.0 0.13 12.9 0.0 2.1 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 EFTUD2 PF16004.5 CDJ52729.1 - 0.4 11.3 0.0 0.4 11.3 0.0 3.7 3 1 0 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus TFIIA PF03153.13 CDJ52729.1 - 1.5 8.7 20.8 1.6 8.7 11.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CytochromB561_N PF09786.9 CDJ52729.1 - 6.4 5.6 6.8 14 4.5 0.2 2.4 2 0 0 2 2 2 0 Cytochrome B561, N terminal ABC_tran PF00005.27 CDJ52730.1 - 3.8e-21 76.0 0.0 6.6e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CDJ52730.1 - 0.0001 22.3 0.1 0.0002 21.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane PF01061.24 CDJ52730.1 - 0.00025 20.5 0.2 0.00036 20.0 0.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_25 PF13481.6 CDJ52730.1 - 0.0031 17.1 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ52730.1 - 0.0039 16.9 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ52730.1 - 0.0054 16.8 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDJ52730.1 - 0.014 15.8 0.0 0.05 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 CDJ52730.1 - 0.014 15.2 0.0 3.7 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ52730.1 - 0.038 14.5 0.0 0.068 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CDJ52730.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Dynamin family WW PF00397.26 CDJ52731.1 - 0.00011 22.2 0.5 0.00024 21.1 0.5 1.6 1 0 0 1 1 1 1 WW domain HTH_ABP1_N PF18107.1 CDJ52731.1 - 1.1 9.0 6.4 1.1 9.0 1.9 2.6 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain DegT_DnrJ_EryC1 PF01041.17 CDJ52732.1 - 6.1e-11 42.2 0.0 8.9e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3054 PF11255.8 CDJ52732.1 - 0.033 14.7 0.0 0.069 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) Dynein_C PF18199.1 CDJ52733.1 - 3.3e-72 243.3 0.2 9.7e-70 235.2 0.0 2.3 2 0 0 2 2 2 2 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CDJ52733.1 - 5.6e-53 179.3 0.0 1.3e-52 178.1 0.0 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 CDJ52733.1 - 4.8e-35 120.8 0.0 9.7e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CDJ52733.1 - 2e-31 109.3 9.3 2e-31 109.3 9.3 2.5 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CDJ52733.1 - 3.1e-09 37.0 0.0 3.5e-08 33.6 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain HrpB7 PF09486.10 CDJ52733.1 - 0.00028 21.3 3.7 0.00028 21.3 3.7 2.9 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB7) DHR10 PF18595.1 CDJ52733.1 - 0.00037 20.5 6.8 0.00037 20.5 6.8 2.5 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain Spc7 PF08317.11 CDJ52733.1 - 0.003 16.5 4.4 0.003 16.5 4.4 2.4 2 0 0 2 2 2 1 Spc7 kinetochore protein MPS2 PF17060.5 CDJ52733.1 - 0.011 15.1 0.5 0.021 14.1 0.5 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 Sec8_exocyst PF04048.14 CDJ52733.1 - 0.012 15.6 5.7 0.012 15.5 0.3 3.2 3 1 1 4 4 3 0 Sec8 exocyst complex component specific domain UPF0242 PF06785.11 CDJ52733.1 - 0.02 15.0 0.7 0.02 15.0 0.7 2.3 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus FliJ PF02050.16 CDJ52733.1 - 0.057 13.6 6.7 0.048 13.9 3.0 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein ATG16 PF08614.11 CDJ52733.1 - 0.078 13.2 14.0 0.01 16.1 9.3 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CorA PF01544.18 CDJ52733.1 - 0.1 11.9 2.9 0.17 11.2 0.2 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein AcylCoA_dehyd_C PF12186.8 CDJ52733.1 - 0.13 12.4 1.8 1.3 9.2 0.4 3.1 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal DUF4446 PF14584.6 CDJ52733.1 - 0.42 10.6 1.4 1.2 9.1 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) CLZ PF16526.5 CDJ52733.1 - 0.54 10.7 3.7 2.4 8.6 3.7 2.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tropomyosin_1 PF12718.7 CDJ52733.1 - 0.56 10.3 9.2 0.069 13.3 4.2 2.0 2 0 0 2 2 2 0 Tropomyosin like DUF745 PF05335.13 CDJ52733.1 - 0.64 9.7 15.1 0.041 13.6 3.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Sugarporin_N PF11471.8 CDJ52733.1 - 0.69 9.9 5.4 1.5 8.8 0.1 3.1 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DegS PF05384.11 CDJ52733.1 - 0.73 9.3 6.1 0.27 10.7 2.6 2.1 2 0 0 2 2 1 0 Sensor protein DegS BLOC1_2 PF10046.9 CDJ52733.1 - 1 9.7 4.9 0.46 10.8 1.3 2.4 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 CDJ52733.1 - 1.3 9.1 3.9 0.72 9.9 0.9 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 CDJ52733.1 - 2.7 7.5 10.8 0.21 11.1 5.1 2.0 2 1 1 3 3 3 0 Exonuclease VII, large subunit PMEI PF04043.15 CDJ52733.1 - 4 7.8 6.1 27 5.1 0.9 2.7 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor AAA_7 PF12775.7 CDJ52734.1 - 9.9e-28 96.9 0.0 1.5e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_1 PF17857.1 CDJ52734.1 - 5.4e-17 61.8 0.0 1.1e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_6 PF12774.7 CDJ52735.1 - 8.2e-45 153.2 0.4 1.3e-44 152.5 0.2 1.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CDJ52735.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DHC_N2 PF08393.13 CDJ52736.1 - 4.9e-96 322.3 0.3 4.9e-96 322.3 0.3 2.6 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 CDJ52736.1 - 2e-63 214.4 0.0 3.6e-63 213.5 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 CDJ52736.1 - 6.3e-05 23.5 0.0 0.00049 20.7 0.0 2.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDJ52736.1 - 0.00039 20.4 0.0 0.0074 16.3 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ52736.1 - 0.00046 20.6 0.0 0.0023 18.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CDJ52736.1 - 0.049 13.9 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_M PF01031.20 CDJ52736.1 - 0.05 12.8 2.9 0.076 12.2 0.4 2.6 3 0 0 3 3 3 0 Dynamin central region MeaB PF03308.16 CDJ52737.1 - 0.66 8.9 4.8 0.88 8.5 4.8 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2362 PF10154.9 CDJ52737.1 - 0.92 8.4 11.8 1.2 7.9 11.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Exonuc_VII_L PF02601.15 CDJ52737.1 - 0.93 9.0 8.0 1.2 8.7 8.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 CDJ52737.1 - 1.4 7.7 2.4 1.8 7.4 2.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF883 PF05957.13 CDJ52737.1 - 2 9.0 8.2 7.9 7.2 1.3 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Retrotrans_gag PF03732.17 CDJ52737.1 - 3.5 8.0 11.6 9 6.6 11.6 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein Peptidase_A17 PF05380.13 CDJ52737.1 - 8.1 6.4 8.2 1.3 9.0 2.2 2.2 1 1 1 2 2 2 0 Pao retrotransposon peptidase UCH PF00443.29 CDJ52738.1 - 7.9e-46 156.6 0.3 3.6e-45 154.5 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SRP14 PF02290.15 CDJ52738.1 - 3.2e-15 56.3 1.2 3.9e-14 52.8 0.0 3.1 1 1 1 2 2 2 1 Signal recognition particle 14kD protein zf-UBP PF02148.19 CDJ52738.1 - 2.2e-12 47.1 0.3 7.9e-11 42.1 0.0 3.1 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 CDJ52738.1 - 5.8e-12 45.3 0.1 0.00019 21.2 0.0 3.2 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.6 CDJ52738.1 - 5.6e-06 26.2 5.4 0.034 13.8 0.3 3.9 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 CDJ52738.1 - 0.0031 17.2 0.0 0.0088 15.8 0.0 1.8 1 0 0 1 1 1 1 Variant UBP zinc finger Dis3l2_C_term PF17877.1 CDJ52738.1 - 0.87 10.0 9.0 0.35 11.2 0.1 2.8 2 0 0 2 2 2 0 DIS3-like exonuclease 2 C terminal DUF4647 PF15504.6 CDJ52738.1 - 3 6.9 24.8 0.034 13.3 11.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4647) RLL PF10036.9 CDJ52738.1 - 9 6.1 19.4 3 7.6 5.3 4.1 4 0 0 4 4 4 0 RNA transcription, translation and transport factor protein EamA PF00892.20 CDJ52739.1 - 1.1e-10 41.8 20.0 2.2e-10 40.8 13.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family Adaptin_binding PF10199.9 CDJ52740.1 - 0.11 13.1 6.4 0.87 10.2 6.4 2.2 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 V_ATPase_I PF01496.19 CDJ52740.1 - 2.3 6.0 10.2 0.32 8.9 1.7 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family IMUP PF15761.5 CDJ52740.1 - 4 8.2 16.6 2.6 8.8 4.2 2.8 3 0 0 3 3 3 0 Immortalisation up-regulated protein DUF2798 PF11391.8 CDJ52741.1 - 0.028 14.4 1.3 0.06 13.4 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) SR-25 PF10500.9 CDJ52742.1 - 0.13 11.9 7.5 0.2 11.2 7.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ52742.1 - 0.22 11.8 25.9 0.32 11.3 12.2 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Connexin PF00029.19 CDJ52743.1 - 5.1 6.8 7.4 0.67 9.7 0.2 2.7 3 0 0 3 3 3 0 Connexin DMSP_lyase PF16867.5 CDJ52743.1 - 6.2 6.4 10.8 0.28 10.8 4.1 2.3 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase ALMT PF11744.8 CDJ52744.1 - 1.7 7.4 31.3 2.1 7.1 31.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 CDJ52744.1 - 2.3 6.9 36.7 2.8 6.6 36.7 1.1 1 0 0 1 1 1 0 Presenilin DUF5523 PF17661.1 CDJ52744.1 - 8.1 6.0 30.8 10 5.7 30.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CCSAP PF15748.5 CDJ52744.1 - 8.4 6.5 36.1 10 6.2 36.1 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated V_ATPase_I PF01496.19 CDJ52744.1 - 8.7 4.1 38.5 11 3.8 38.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SUIM_assoc PF16619.5 CDJ52746.1 - 0.0046 17.0 0.3 0.0046 17.0 0.3 3.6 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 dsDNA_bind PF01984.20 CDJ52746.1 - 1.7 8.9 13.0 6.9 7.0 4.1 2.3 2 0 0 2 2 2 0 Double-stranded DNA-binding domain DUF2722 PF10846.8 CDJ52747.1 - 0.00065 18.8 0.3 0.001 18.1 0.3 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) SARAF PF06682.12 CDJ52747.1 - 0.011 15.4 4.2 1.6 8.3 4.1 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CCDC53 PF10152.9 CDJ52747.1 - 0.14 12.6 3.9 0.2 12.0 0.3 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Transcrip_act PF04949.13 CDJ52748.1 - 0.021 14.7 1.1 0.021 14.7 1.1 1.9 2 0 0 2 2 2 0 Transcriptional activator PP2C_2 PF13672.6 CDJ52748.1 - 1.2 8.8 16.6 2 8.0 16.6 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C SR-25 PF10500.9 CDJ52748.1 - 2.5 7.7 42.8 30 4.1 16.8 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 CDJ52748.1 - 8.4 3.4 30.5 11 3.0 30.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Roughex PF06020.11 CDJ52749.1 - 0.14 11.2 9.4 0.21 10.7 9.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein PIP49_C PF12260.8 CDJ52749.1 - 0.28 10.8 6.9 0.46 10.1 6.9 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 CytochromB561_N PF09786.9 CDJ52749.1 - 3.2 6.6 22.8 4.1 6.3 22.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Bud13 PF09736.9 CDJ52749.1 - 5.4 7.4 10.9 0.84 10.0 6.1 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Presenilin PF01080.17 CDJ52750.1 - 0.047 12.5 31.2 0.052 12.3 31.2 1.0 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 CDJ52750.1 - 0.23 11.6 27.5 0.31 11.1 27.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SLC12 PF03522.15 CDJ52750.1 - 0.61 9.0 26.6 0.77 8.7 26.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SURF2 PF05477.11 CDJ52750.1 - 0.74 9.5 26.9 0.96 9.1 26.9 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF4551 PF15087.6 CDJ52750.1 - 0.86 8.4 23.6 1 8.1 23.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PPP4R2 PF09184.11 CDJ52750.1 - 2.3 7.7 18.8 3.4 7.2 18.8 1.2 1 0 0 1 1 1 0 PPP4R2 XRN_M PF17846.1 CDJ52750.1 - 3 6.7 19.2 3.9 6.3 19.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Connexin PF00029.19 CDJ52750.1 - 5.9 6.6 24.2 0.69 9.6 10.6 2.0 2 0 0 2 2 2 0 Connexin SRP-alpha_N PF04086.13 CDJ52750.1 - 8.6 6.2 30.9 11 5.8 30.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4820 PF16091.5 CDJ52750.1 - 9.2 5.6 22.4 3.3 7.0 10.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF2722 PF10846.8 CDJ52751.1 - 0.0037 16.3 6.1 0.0037 16.3 6.1 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 CDJ52751.1 - 0.15 11.0 33.4 0.84 8.5 1.5 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TCP PF03634.13 CDJ52751.1 - 0.97 10.0 28.4 2.9 8.4 15.9 2.7 2 0 0 2 2 2 0 TCP family transcription factor SID-1_RNA_chan PF13965.6 CDJ52751.1 - 1.2 7.4 6.3 0.21 9.9 1.9 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 CDJ52751.1 - 2.5 7.8 33.4 0.39 10.5 18.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF1387 PF07139.11 CDJ52751.1 - 4.5 6.9 29.9 2.3 7.8 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) MMR1 PF08505.10 CDJ52751.1 - 7.5 6.8 37.6 0.79 10.0 2.5 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Draxin PF15550.6 CDJ52751.1 - 9.5 6.0 24.9 5.1 6.9 12.8 2.6 2 0 0 2 2 2 0 Draxin WD40 PF00400.32 CDJ52752.1 - 8.5e-06 26.4 0.4 0.00024 21.8 0.4 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat SR-25 PF10500.9 CDJ52752.1 - 0.00015 21.5 49.4 0.00096 18.8 29.5 5.8 5 0 0 5 5 5 2 Nuclear RNA-splicing-associated protein ANAPC4_WD40 PF12894.7 CDJ52752.1 - 0.0003 21.0 0.0 0.0018 18.6 0.0 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RskA PF10099.9 CDJ52752.1 - 0.014 15.7 0.0 0.014 15.7 0.0 13.7 2 2 4 8 8 8 0 Anti-sigma-K factor rskA DUF913 PF06025.12 CDJ52753.1 - 0.0052 15.8 25.4 0.0097 14.9 4.5 2.1 2 0 0 2 2 2 2 Domain of Unknown Function (DUF913) Utp14 PF04615.13 CDJ52753.1 - 0.69 8.4 47.5 0.89 8.0 47.5 1.0 1 0 0 1 1 1 0 Utp14 protein RR_TM4-6 PF06459.12 CDJ52753.1 - 1.2 8.9 48.7 0.47 10.2 16.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ52753.1 - 1.4 8.9 34.7 0.88 9.5 11.4 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Exonuc_VII_L PF02601.15 CDJ52753.1 - 1.9 8.0 55.3 0.63 9.6 20.7 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit PA26 PF04636.13 CDJ52753.1 - 3.1 6.6 33.6 0.62 8.9 10.7 2.3 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) AAA_11 PF13086.6 CDJ52753.1 - 4 7.1 44.0 0.52 10.0 15.6 2.2 2 0 0 2 2 2 0 AAA domain AF-4 PF05110.13 CDJ52753.1 - 7.2 4.6 52.0 0.45 8.6 21.9 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein MIIP PF15734.5 CDJ52753.1 - 7.3 6.0 42.3 0.62 9.5 15.9 2.2 2 0 0 2 2 2 0 Migration and invasion-inhibitory Presenilin PF01080.17 CDJ52753.1 - 9.7 4.8 57.7 2.6 6.7 24.9 2.1 2 0 0 2 2 2 0 Presenilin PepSY_2 PF13670.6 CDJ52754.1 - 0.044 13.8 1.5 0.044 13.8 1.5 4.1 3 1 2 5 5 5 0 Peptidase propeptide and YPEB domain FAST_2 PF08368.12 CDJ52754.1 - 2.2 9.1 8.1 25 5.7 0.0 3.4 3 1 0 3 3 3 0 FAST kinase-like protein, subdomain 2 FAM199X PF15814.5 CDJ52754.1 - 3.4 6.6 11.6 7.2 5.6 11.6 1.5 1 0 0 1 1 1 0 Protein family FAM199X DUF4192 PF13830.6 CDJ52754.1 - 7.9 6.4 21.7 0.83 9.7 11.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) GatB_N PF02934.15 CDJ52755.1 - 1.4e-66 224.7 0.1 9.3e-60 202.3 0.0 2.7 2 1 1 3 3 3 2 GatB/GatE catalytic domain LAX PF15681.5 CDJ52755.1 - 0.078 11.8 1.9 0.13 11.1 1.9 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X eIF3g PF12353.8 CDJ52755.1 - 0.44 10.9 5.0 25 5.3 0.6 3.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G baeRF_family12 PF18856.1 CDJ52756.1 - 1.6 9.3 8.5 1.9 9.1 8.5 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 CDK2AP PF09806.9 CDJ52756.1 - 1.9 8.5 15.6 2.3 8.2 15.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein MDFI PF15316.6 CDJ52756.1 - 8.7 6.4 7.8 10 6.2 7.8 1.1 1 0 0 1 1 1 0 MyoD family inhibitor AAA_23 PF13476.6 CDJ52757.1 - 0.46 10.9 24.1 0.18 12.3 8.0 2.3 2 0 0 2 2 2 0 AAA domain SAGA-Tad1 PF12767.7 CDJ52757.1 - 0.62 9.8 23.4 2 8.1 11.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF572 PF04502.13 CDJ52757.1 - 0.69 9.5 21.6 1.2 8.7 8.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) Tubulin_3 PF14881.6 CDJ52757.1 - 1.4 8.5 6.1 0.26 10.9 0.5 2.4 2 0 0 2 2 2 0 Tubulin domain DUF1788 PF08747.11 CDJ52757.1 - 1.6 8.7 6.2 5.2 7.1 6.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) IMUP PF15761.5 CDJ52757.1 - 2 9.1 15.9 0.14 12.8 0.6 3.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein YfhO PF09586.10 CDJ52758.1 - 0.34 9.1 7.4 0.33 9.1 7.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RskA PF10099.9 CDJ52760.1 - 0.00032 21.0 11.0 0.00045 20.6 11.0 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Macoilin PF09726.9 CDJ52760.1 - 0.045 12.3 26.1 0.051 12.1 26.1 1.3 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CDJ52760.1 - 0.061 13.3 21.1 0.064 13.2 21.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 CDJ52760.1 - 1 7.7 5.7 1.3 7.3 5.7 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF572 PF04502.13 CDJ52760.1 - 2.4 7.7 22.6 2.7 7.5 22.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Raftlin PF15250.6 CDJ52760.1 - 4.2 6.0 17.1 4.4 5.9 17.1 1.2 1 0 0 1 1 1 0 Raftlin Utp14 PF04615.13 CDJ52760.1 - 4.5 5.7 22.2 4.7 5.6 22.2 1.0 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 CDJ52760.1 - 5.1 4.1 31.7 5.3 4.0 31.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 CDJ52760.1 - 8.4 5.3 15.2 9.5 5.1 15.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Cytochrom_B_N_2 PF13631.6 CDJ52762.1 - 0.16 12.0 0.4 18 5.3 0.0 3.9 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB CS PF04969.16 CDJ52764.1 - 4.9e-15 56.3 0.0 9.7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 CDJ52764.1 - 1.3e-11 44.3 0.3 2.6e-11 43.4 0.3 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Ribosomal_60s PF00428.19 CDJ52764.1 - 0.21 12.2 12.6 0.54 10.9 12.6 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Comm PF15957.5 CDJ52764.1 - 0.22 11.9 1.5 0.67 10.3 1.5 1.8 1 0 0 1 1 1 0 Commissureless Plasmodium_Vir PF05795.11 CDJ52764.1 - 0.33 10.3 8.5 0.058 12.8 4.6 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Spt20 PF12090.8 CDJ52764.1 - 0.35 10.4 29.7 0.015 14.9 21.9 2.1 2 0 0 2 2 2 0 Spt20 family FGF-BP1 PF06473.12 CDJ52764.1 - 0.43 10.4 0.1 0.43 10.4 0.1 3.5 2 2 1 3 3 2 0 FGF binding protein 1 (FGF-BP1) DUF2722 PF10846.8 CDJ52764.1 - 1.4 7.8 24.4 0.023 13.7 17.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4718 PF15842.5 CDJ52764.1 - 2.3 8.0 7.5 4.5 7.0 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Presenilin PF01080.17 CDJ52764.1 - 3.5 6.3 17.9 0.22 10.3 13.0 1.5 2 0 0 2 2 2 0 Presenilin MMR1 PF08505.10 CDJ52764.1 - 4.8 7.4 20.0 0.95 9.7 14.4 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Leu_zip PF15294.6 CDJ52765.1 - 0.0076 15.8 13.4 0.0076 15.8 13.4 2.2 1 1 1 2 2 2 1 Leucine zipper PikAIV_N PF18605.1 CDJ52765.1 - 0.01 15.4 3.6 0.01 15.4 3.6 4.5 4 1 1 5 5 5 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain CCDC92 PF14916.6 CDJ52765.1 - 0.01 15.6 1.5 1.2 8.9 0.2 2.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Mfa1 PF17445.2 CDJ52765.1 - 0.037 14.0 0.2 0.098 12.7 0.2 1.6 1 0 0 1 1 1 0 Mating factor A1 GIT_CC PF16559.5 CDJ52765.1 - 0.2 11.5 11.0 0.38 10.7 0.3 3.7 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor HAP1_N PF04849.13 CDJ52765.1 - 0.33 10.1 22.9 0.041 13.1 18.4 1.6 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Spc7 PF08317.11 CDJ52765.1 - 1.8 7.4 16.8 1.5 7.6 11.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 CDJ52765.1 - 4.9 7.2 16.8 1.1 9.4 13.4 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 CDJ52765.1 - 7 6.8 23.6 0.04 14.1 11.3 2.6 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 CDJ52765.1 - 8.1 5.9 13.4 13 5.3 13.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit YabA PF06156.13 CDJ52765.1 - 9.2 7.0 14.4 2.1 9.1 0.5 3.6 1 1 3 4 4 4 0 Initiation control protein YabA Fez1 PF06818.15 CDJ52765.1 - 9.5 6.6 21.4 0.68 10.4 6.3 2.9 1 1 2 3 3 3 0 Fez1 Myb_DNA-binding PF00249.31 CDJ52767.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain EF-hand_6 PF13405.6 CDJ52768.1 - 0.002 17.9 0.0 0.041 13.8 0.0 2.7 2 1 0 2 2 2 1 EF-hand domain SUIM_assoc PF16619.5 CDJ52768.1 - 0.038 14.1 0.3 0.038 14.1 0.3 7.3 6 1 0 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 CSN8_PSD8_EIF3K PF10075.9 CDJ52769.1 - 1.9e-07 31.1 1.1 5.2e-05 23.2 0.8 3.9 4 1 1 5 5 5 2 CSN8/PSMD8/EIF3K family LEDGF PF11467.8 CDJ52769.1 - 0.053 13.1 0.4 0.053 13.1 0.4 2.3 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) PCI PF01399.27 CDJ52769.1 - 0.074 13.6 0.5 0.074 13.6 0.5 2.6 3 0 0 3 3 3 0 PCI domain RT_RNaseH_2 PF17919.1 CDJ52772.1 - 1.3e-06 28.4 0.0 2.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PAM2 PF07145.15 CDJ52773.1 - 8.4e-05 22.0 1.4 0.00019 20.9 1.4 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region RskA PF10099.9 CDJ52774.1 - 0.0064 16.8 10.1 0.0064 16.8 10.1 3.5 4 1 0 4 4 4 1 Anti-sigma-K factor rskA Chorismate_synt PF01264.21 CDJ52775.1 - 3.1e-38 131.3 9.8 8.5e-38 129.9 8.8 2.1 1 1 0 1 1 1 1 Chorismate synthase Tim54 PF11711.8 CDJ52775.1 - 0.00094 18.1 10.7 0.00094 18.1 10.7 2.0 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 CDJ52775.1 - 0.027 12.8 14.5 0.045 12.1 14.5 1.3 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.6 CDJ52775.1 - 0.59 10.1 17.1 0.37 10.8 13.6 2.0 2 0 0 2 2 2 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ52775.1 - 0.84 9.4 33.0 1.3 8.8 26.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 CDJ52775.1 - 1.2 7.0 17.8 1.7 6.5 17.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2828 PF11443.8 CDJ52775.1 - 1.9 6.5 17.9 3.2 5.7 17.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4045 PF13254.6 CDJ52775.1 - 2.9 7.4 30.9 4.4 6.8 21.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) NPR3 PF03666.13 CDJ52775.1 - 3.3 6.4 19.8 0.11 11.2 14.1 1.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Band_3_cyto PF07565.13 CDJ52775.1 - 5.3 6.8 26.3 1.8 8.3 22.8 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Cellulose_synt PF03552.14 CDJ52775.1 - 8.4 4.7 5.7 13 4.2 5.7 1.2 1 0 0 1 1 1 0 Cellulose synthase SAPS PF04499.15 CDJ52775.1 - 9.6 4.9 20.5 15 4.3 15.1 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF1387 PF07139.11 CDJ52775.1 - 10 5.8 25.3 3.9 7.1 21.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) DUF3689 PF12463.8 CDJ52777.1 - 9e-22 77.8 3.9 4.2e-13 49.3 0.1 3.7 3 1 1 4 4 4 2 Protein of unknown function (DUF3689) Utp14 PF04615.13 CDJ52777.1 - 0.00073 18.2 26.2 0.00073 18.2 26.2 2.4 3 0 0 3 3 3 2 Utp14 protein NAM-associated PF14303.6 CDJ52777.1 - 0.0017 19.1 0.0 0.0017 19.1 0.0 7.1 3 2 2 5 5 5 1 No apical meristem-associated C-terminal domain Nha1_C PF08619.10 CDJ52777.1 - 0.0068 15.7 1.7 0.0068 15.7 1.7 4.6 4 1 0 4 4 4 1 Alkali metal cation/H+ antiporter Nha1 C terminus RskA PF10099.9 CDJ52777.1 - 0.016 15.5 8.7 0.016 15.5 8.7 6.5 3 2 3 6 6 6 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ52777.1 - 0.017 15.7 16.4 0.23 12.1 9.0 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ52778.1 - 4 7.7 63.6 0.08 13.2 16.6 4.0 1 1 2 3 3 3 0 Anti-sigma-K factor rskA UPF0172 PF03665.13 CDJ52779.1 - 7.9e-20 71.7 0.0 1.8e-19 70.5 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) Prok-JAB PF14464.6 CDJ52779.1 - 0.0052 16.6 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 CDJ52779.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1772 PF08592.11 CDJ52780.1 - 0.00051 20.4 8.8 0.0022 18.3 1.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) DUF2722 PF10846.8 CDJ52780.1 - 0.00089 18.3 11.9 0.00089 18.3 11.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF719 PF05334.13 CDJ52780.1 - 0.0026 18.0 0.5 0.0026 18.0 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF719) Folliculin PF11704.8 CDJ52780.1 - 0.01 15.8 3.6 0.24 11.2 1.8 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport RskA PF10099.9 CDJ52780.1 - 0.024 14.9 63.1 0.35 11.1 24.2 2.7 2 1 0 2 2 2 0 Anti-sigma-K factor rskA MecA PF05389.12 CDJ52780.1 - 0.035 13.8 0.8 0.035 13.8 0.8 1.8 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Peptidase_S49_N PF08496.10 CDJ52780.1 - 0.056 13.5 0.6 0.056 13.5 0.6 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TFIIA PF03153.13 CDJ52780.1 - 0.081 12.9 46.0 0.47 10.4 25.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peroxin-13_N PF04088.13 CDJ52780.1 - 0.091 13.0 3.5 0.41 10.9 0.6 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region FAM60A PF15396.6 CDJ52780.1 - 0.12 12.4 1.9 0.39 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein Family FAM60A SpoIIP PF07454.11 CDJ52780.1 - 0.13 11.7 6.4 0.033 13.6 2.1 1.8 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Sporozoite_P67 PF05642.11 CDJ52780.1 - 0.15 10.1 0.0 0.2 9.7 0.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4834 PF16118.5 CDJ52780.1 - 0.18 12.8 14.2 0.063 14.3 5.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Suf PF05843.14 CDJ52780.1 - 0.2 11.6 17.3 0.03 14.3 6.3 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Connexin PF00029.19 CDJ52780.1 - 0.25 11.1 2.7 0.24 11.1 0.6 1.8 2 0 0 2 2 2 0 Connexin FHIPEP PF00771.20 CDJ52780.1 - 0.27 9.6 10.9 0.053 12.0 4.0 2.0 2 0 0 2 2 2 0 FHIPEP family CPSF100_C PF13299.6 CDJ52780.1 - 0.34 11.1 7.8 0.13 12.4 1.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EOS1 PF12326.8 CDJ52780.1 - 0.37 10.7 1.4 1.4 8.8 0.4 1.9 2 0 0 2 2 2 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ52780.1 - 0.45 9.4 14.5 0.049 12.6 5.3 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CTU2 PF10288.9 CDJ52780.1 - 0.52 10.6 7.3 0.37 11.1 2.4 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Bac_luciferase PF00296.20 CDJ52780.1 - 0.54 9.6 27.6 0.097 12.1 7.6 2.1 2 0 0 2 2 2 0 Luciferase-like monooxygenase V_ATPase_I PF01496.19 CDJ52780.1 - 0.55 8.1 8.7 0.036 12.0 3.2 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1980 PF09323.10 CDJ52780.1 - 0.58 10.0 3.3 0.56 10.1 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4820 PF16091.5 CDJ52780.1 - 0.79 9.0 9.1 0.42 9.9 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Eapp_C PF10238.9 CDJ52780.1 - 0.93 9.6 10.6 0.28 11.3 5.1 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein Neur_chan_memb PF02932.16 CDJ52780.1 - 0.98 9.4 4.8 0.61 10.1 0.5 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 CDJ52780.1 - 1.1 8.1 4.7 0.27 10.1 1.6 1.4 2 0 0 2 2 2 0 Serine incorporator (Serinc) Rpp20 PF12328.8 CDJ52780.1 - 1.9 8.5 10.2 1.4 8.9 5.4 2.2 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P AAA_23 PF13476.6 CDJ52780.1 - 1.9 8.9 13.8 4.2 7.8 9.7 2.1 2 0 0 2 2 2 0 AAA domain FPN1 PF06963.12 CDJ52780.1 - 2.2 6.7 14.0 1.1 7.8 5.0 2.4 2 1 1 3 3 3 0 Ferroportin1 (FPN1) EIIBC-GUT_N PF03612.14 CDJ52780.1 - 2.3 7.9 9.4 1.6 8.4 5.5 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus CLN3 PF02487.17 CDJ52780.1 - 2.5 7.1 4.7 0.42 9.6 0.8 1.6 2 0 0 2 2 2 0 CLN3 protein NEMP PF10225.9 CDJ52780.1 - 3 7.5 4.5 1.1 8.9 1.0 1.8 2 0 0 2 2 2 0 NEMP family RR_TM4-6 PF06459.12 CDJ52780.1 - 3 7.6 11.5 0.93 9.3 4.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3391 PF11871.8 CDJ52780.1 - 3.9 8.0 16.3 0.28 11.7 2.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF677 PF05055.12 CDJ52780.1 - 4.3 6.1 6.6 0.36 9.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF677) G0-G1_switch_2 PF15103.6 CDJ52780.1 - 4.9 7.6 10.5 2.7 8.5 4.3 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 FYDLN_acid PF09538.10 CDJ52780.1 - 5.9 7.6 8.2 0.71 10.6 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Gti1_Pac2 PF09729.9 CDJ52780.1 - 6.5 6.8 7.8 12 5.9 7.8 1.5 1 1 0 1 1 1 0 Gti1/Pac2 family Pex26 PF07163.12 CDJ52780.1 - 7.6 5.7 15.0 3.4 6.9 8.0 2.3 2 0 0 2 2 2 0 Pex26 protein DUF3464 PF11947.8 CDJ52780.1 - 7.8 6.2 13.5 1 9.1 5.6 2.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4770 PF15994.5 CDJ52780.1 - 9.6 6.4 14.6 2.2 8.5 7.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) TFIIA PF03153.13 CDJ52781.1 - 0.00071 19.7 28.4 0.00071 19.7 28.4 11.8 3 2 4 9 9 9 2 Transcription factor IIA, alpha/beta subunit DNA_primase_lrg PF04104.14 CDJ52781.1 - 0.00077 18.9 0.0 0.0063 15.9 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit His_Phos_1 PF00300.22 CDJ52782.1 - 2.7e-33 115.3 0.0 3.5e-25 88.8 0.1 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Med3 PF11593.8 CDJ52782.1 - 0.069 12.3 1.3 0.091 11.9 1.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TAF6_C PF07571.13 CDJ52782.1 - 0.1 13.0 0.0 0.55 10.6 0.0 2.1 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain DUF2057 PF09829.9 CDJ52782.1 - 0.98 9.6 4.1 1.5 8.9 4.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF966 PF06136.13 CDJ52783.1 - 7.1 6.2 16.4 8.5 6.0 16.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF418 PF04235.12 CDJ52784.1 - 0.2 11.6 0.4 0.37 10.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF418) DUF2407_C PF13373.6 CDJ52786.1 - 5.4 7.2 5.5 0.75 10.0 0.3 2.1 3 0 0 3 3 3 0 DUF2407 C-terminal domain Asp_protease_2 PF13650.6 CDJ52787.1 - 3.4e-08 34.0 0.0 6.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ52787.1 - 5.7e-07 30.0 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ52787.1 - 0.033 14.0 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ52787.1 - 0.033 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 CDJ52787.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 CDJ52788.1 - 2.1e-21 75.8 0.1 3.2e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ52788.1 - 1.7e-17 63.6 0.0 3.9e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ52788.1 - 0.0039 16.7 0.0 0.008 15.7 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ52789.1 - 9.8e-14 51.6 0.0 2.4e-13 50.3 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ52789.1 - 1.8e-10 40.8 0.1 5.1e-10 39.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ52789.1 - 0.014 15.2 0.1 0.41 10.5 0.1 2.4 2 0 0 2 2 2 0 Integrase core domain SecM PF06558.12 CDJ52789.1 - 0.025 14.7 0.1 0.061 13.4 0.1 1.7 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) AUX_IAA PF02309.16 CDJ52790.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 AUX/IAA family PIP5K PF01504.18 CDJ52791.1 - 0.1 11.8 1.9 0.16 11.2 1.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_S49_N PF08496.10 CDJ52791.1 - 0.14 12.2 5.2 1.3 9.1 1.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Rpp20 PF12328.8 CDJ52791.1 - 0.22 11.5 4.4 9.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P CNDH2_N PF06278.11 CDJ52791.1 - 0.78 10.0 5.8 6.8 6.9 0.4 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal EphA2_TM PF14575.6 CDJ52791.1 - 0.96 10.4 5.6 21 6.1 1.3 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain EPL1 PF10513.9 CDJ52791.1 - 2.8 8.3 8.5 13 6.2 0.8 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like PAT1 PF09770.9 CDJ52791.1 - 8.8 4.5 18.9 11 4.1 18.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 dsDNA_bind PF01984.20 CDJ52791.1 - 9.2 6.6 24.3 3.5 7.9 7.4 2.6 2 0 0 2 2 2 0 Double-stranded DNA-binding domain AAA PF00004.29 CDJ52792.1 - 1.6e-07 31.8 0.8 0.00081 19.8 0.1 3.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SUIM_assoc PF16619.5 CDJ52792.1 - 0.013 15.6 2.7 0.013 15.6 2.7 9.1 5 4 2 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 DnaJ PF00226.31 CDJ52793.1 - 0.017 15.2 0.1 0.07 13.3 0.1 2.1 1 0 0 1 1 1 0 DnaJ domain DUF572 PF04502.13 CDJ52793.1 - 0.029 14.0 30.7 0.18 11.4 3.5 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF572) Med19 PF10278.9 CDJ52793.1 - 0.2 11.6 9.3 0.69 9.8 9.3 1.8 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 O-antigen_lig PF13425.6 CDJ52793.1 - 0.25 10.1 4.7 0.44 9.3 4.7 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Folate_carrier PF01770.18 CDJ52793.1 - 1.2 7.8 5.5 3.7 6.2 5.5 1.8 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.20 CDJ52793.1 - 9.7 4.3 6.3 5.9 5.1 3.2 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family UL97 PF06734.12 CDJ52794.1 - 0.045 13.7 0.6 0.092 12.6 0.6 1.4 1 0 0 1 1 1 0 UL97 Sod_Fe_N PF00081.22 CDJ52794.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.4 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Presenilin PF01080.17 CDJ52795.1 - 0.0004 19.3 9.1 0.0004 19.3 9.1 8.8 4 2 0 5 5 5 1 Presenilin RskA PF10099.9 CDJ52795.1 - 0.019 15.3 0.0 0.019 15.3 0.0 17.5 6 4 6 13 13 13 0 Anti-sigma-K factor rskA TAF4 PF05236.14 CDJ52795.1 - 2.6 7.7 0.0 2.6 7.7 0.0 11.7 5 2 3 9 9 9 0 Transcription initiation factor TFIID component TAF4 family tRNA-synt_2b PF00587.25 CDJ52796.1 - 1.3e-31 110.0 0.0 3.6e-29 102.0 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CDJ52796.1 - 6.8e-20 71.3 1.3 6.8e-20 71.3 1.3 2.1 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DNA_primase_lrg PF04104.14 CDJ52796.1 - 0.019 14.4 0.2 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit RCR PF12273.8 CDJ52796.1 - 0.032 14.9 2.2 0.087 13.5 2.2 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TFIIA PF03153.13 CDJ52796.1 - 0.11 12.5 13.6 0.021 14.8 8.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ52796.1 - 0.13 11.9 19.5 0.23 11.1 19.5 1.3 1 0 0 1 1 1 0 Spt20 family Mitofilin PF09731.9 CDJ52796.1 - 1.2 7.9 10.9 0.19 10.5 2.9 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein SARAF PF06682.12 CDJ52796.1 - 7.8 6.0 10.0 0.05 13.2 1.5 1.6 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis TCTP PF00838.17 CDJ52797.1 - 6.8e-42 143.6 2.2 7.8e-42 143.4 2.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Rtf2 PF04641.12 CDJ52799.1 - 0.72 9.2 25.1 0.83 9.0 25.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Apt1 PF10351.9 CDJ52799.1 - 0.74 8.6 23.4 0.84 8.4 23.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain NARP1 PF12569.8 CDJ52799.1 - 1 8.2 26.4 1.1 8.0 26.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 CDJ52799.1 - 1 8.0 39.1 1.2 7.9 39.1 1.0 1 0 0 1 1 1 0 Presenilin DUF1168 PF06658.12 CDJ52799.1 - 1.2 8.9 33.9 1.5 8.7 33.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CSG2 PF16965.5 CDJ52799.1 - 2 7.3 15.7 2.1 7.2 15.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Bac_luciferase PF00296.20 CDJ52799.1 - 2.2 7.6 8.6 2.8 7.3 8.6 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF4569 PF15133.6 CDJ52799.1 - 2.3 7.8 32.0 2.8 7.6 32.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF2828 PF11443.8 CDJ52799.1 - 2.7 5.9 27.8 3.2 5.7 27.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Paf1 PF03985.13 CDJ52799.1 - 2.8 6.8 34.7 3.4 6.6 34.7 1.1 1 0 0 1 1 1 0 Paf1 PPL5 PF18168.1 CDJ52799.1 - 3 7.0 19.3 4 6.6 19.3 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DUF4746 PF15928.5 CDJ52799.1 - 3.6 6.9 23.6 4.6 6.6 23.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) V_ATPase_I PF01496.19 CDJ52799.1 - 3.9 5.3 29.8 4.4 5.1 29.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gti1_Pac2 PF09729.9 CDJ52799.1 - 5.5 7.0 25.0 7.3 6.6 25.0 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family RR_TM4-6 PF06459.12 CDJ52799.1 - 5.6 6.7 32.9 6.7 6.4 32.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3381 PF11861.8 CDJ52799.1 - 7.9 6.3 32.1 9.2 6.0 32.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF2151 PF10221.9 CDJ52799.1 - 9.3 4.7 18.2 9.8 4.6 18.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator ALMT PF11744.8 CDJ52799.1 - 9.6 4.9 25.1 11 4.7 25.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF572 PF04502.13 CDJ52799.1 - 9.7 5.7 28.7 11 5.6 28.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) MMU163 PF17119.5 CDJ52799.1 - 10 5.2 17.0 12 5.0 17.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Ndc1_Nup PF09531.10 CDJ52800.1 - 0.28 9.8 3.9 0.3 9.7 3.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM199X PF15814.5 CDJ52800.1 - 3.1 6.8 11.0 3.7 6.5 11.0 1.0 1 0 0 1 1 1 0 Protein family FAM199X EXOSC1 PF10447.9 CDJ52801.1 - 1.1e-10 42.1 1.5 1.2e-06 29.1 0.0 2.6 2 1 1 3 3 3 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 CDJ52801.1 - 0.0085 15.9 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Nop14 PF04147.12 CDJ52802.1 - 0.013 13.8 20.6 0.015 13.6 20.6 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDJ52802.1 - 0.59 8.4 29.2 0.75 8.0 29.2 1.3 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 CDJ52802.1 - 1.2 8.1 15.9 1.4 7.9 15.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 CDJ52802.1 - 2.2 7.0 21.6 2.6 6.7 21.6 1.2 1 0 0 1 1 1 0 Presenilin RAP PF08373.10 CDJ52803.1 - 1.3e-13 50.8 0.0 2.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 RAP domain DDHD PF02862.17 CDJ52803.1 - 0.011 16.0 2.4 0.011 16.0 2.4 2.8 2 1 0 2 2 2 0 DDHD domain Band_3_cyto PF07565.13 CDJ52803.1 - 0.18 11.6 34.8 0.13 12.1 16.8 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2052 PF09747.9 CDJ52803.1 - 0.87 9.7 39.8 0.018 15.2 20.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) AF-4 PF05110.13 CDJ52803.1 - 0.9 7.5 56.2 0.22 9.6 34.3 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Exonuc_VII_L PF02601.15 CDJ52803.1 - 0.91 9.0 36.8 0.29 10.7 17.3 2.6 3 0 0 3 3 3 0 Exonuclease VII, large subunit RskA PF10099.9 CDJ52805.1 - 6.2e-05 23.4 10.2 6.2e-05 23.4 10.2 12.5 2 2 6 9 9 9 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ52805.1 - 0.0032 16.5 5.5 0.0032 16.5 5.5 7.4 3 2 3 6 6 6 1 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ52805.1 - 0.0072 16.0 9.5 0.0072 16.0 9.5 5.7 2 1 3 5 5 5 1 Nuclear RNA-splicing-associated protein SAM_1 PF00536.30 CDJ52805.1 - 0.011 16.2 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SMC_N PF02463.19 CDJ52806.1 - 3.2e-23 82.3 9.7 1.3e-17 64.0 6.6 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ52806.1 - 1.9e-11 44.4 0.0 5.5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_hinge PF06470.13 CDJ52806.1 - 9.8e-11 42.0 0.0 9.8e-11 42.0 0.0 4.1 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain SUIM_assoc PF16619.5 CDJ52806.1 - 0.0055 16.7 0.0 0.0055 16.7 0.0 18.5 13 6 6 19 19 19 1 Unstructured region C-term to UIM in Ataxin3 RRP36 PF06102.12 CDJ52807.1 - 4.1e-26 91.9 21.0 4.1e-26 91.9 21.0 3.1 2 1 1 3 3 3 2 rRNA biogenesis protein RRP36 DUF2986 PF11661.8 CDJ52807.1 - 0.039 14.5 8.4 0.039 14.5 8.4 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2986) DUF2722 PF10846.8 CDJ52808.1 - 0.0025 16.8 20.6 0.0025 16.8 20.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52808.1 - 0.39 10.3 82.9 0.021 14.4 33.7 2.2 2 0 0 2 2 2 0 Spt20 family Connexin PF00029.19 CDJ52808.1 - 2.6 7.7 21.8 0.64 9.7 4.1 2.1 2 0 0 2 2 2 0 Connexin FAM176 PF14851.6 CDJ52808.1 - 9 5.9 19.9 6.7 6.4 7.1 2.2 2 0 0 2 2 2 0 FAM176 family FAM76 PF16046.5 CDJ52808.1 - 9.1 5.5 31.6 2 7.7 11.6 2.0 2 0 0 2 2 2 0 FAM76 protein DUF2722 PF10846.8 CDJ52809.1 - 8.8e-06 24.9 7.1 8.8e-06 24.9 7.1 12.7 10 3 2 12 12 12 3 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ52809.1 - 9.1e-05 22.8 3.2 0.00031 21.1 0.7 14.6 5 2 6 12 12 12 6 Anti-sigma-K factor rskA Seadorna_VP6 PF07407.11 CDJ52809.1 - 0.2 10.6 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein HNOBA PF07701.14 CDJ52809.1 - 1.7 8.0 0.0 1.7 8.0 0.0 9.4 4 3 2 7 7 7 0 Heme NO binding associated RskA PF10099.9 CDJ52811.1 - 0.00099 19.4 51.1 17 5.7 31.1 4.0 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Borrelia_P83 PF05262.11 CDJ52811.1 - 0.033 12.7 9.0 0.046 12.2 9.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SPX PF03105.19 CDJ52811.1 - 0.17 11.8 18.6 0.08 12.9 13.5 1.9 1 1 1 2 2 2 0 SPX domain Activator_LAG-3 PF11498.8 CDJ52811.1 - 0.51 9.2 54.2 1.4 7.8 54.2 1.7 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Bud13 PF09736.9 CDJ52811.1 - 0.92 9.9 12.4 2 8.8 12.4 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex eIF-3_zeta PF05091.12 CDJ52811.1 - 1.1 8.2 13.5 1.5 7.7 13.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SOBP PF15279.6 CDJ52811.1 - 8.6 6.9 27.4 1.1 9.8 20.6 2.0 2 0 0 2 2 2 0 Sine oculis-binding protein SPX PF03105.19 CDJ52812.1 - 0.0028 17.7 20.8 0.0038 17.2 20.8 1.4 1 1 0 1 1 1 1 SPX domain DUF572 PF04502.13 CDJ52812.1 - 0.047 13.3 6.3 0.059 13.0 6.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GREB1 PF15782.5 CDJ52812.1 - 5.1 4.1 13.8 7.8 3.5 13.8 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RskA PF10099.9 CDJ52813.1 - 0.014 15.7 7.0 0.014 15.7 7.0 3.2 1 1 2 3 3 3 0 Anti-sigma-K factor rskA PAP2 PF01569.21 CDJ52813.1 - 0.079 12.7 3.1 0.17 11.6 3.1 1.7 1 1 0 1 1 1 0 PAP2 superfamily AF-4 PF05110.13 CDJ52814.1 - 0.0019 16.4 22.2 0.0019 16.4 22.2 4.4 3 2 1 4 4 4 1 AF-4 proto-oncoprotein Tic110 PF16940.5 CDJ52814.1 - 0.0033 16.0 3.2 0.0033 16.0 3.2 3.3 3 0 0 3 3 3 1 Chloroplast envelope transporter Spt20 PF12090.8 CDJ52814.1 - 0.011 15.4 33.3 0.011 15.4 33.3 9.3 3 1 1 4 4 4 0 Spt20 family FA_desaturase PF00487.24 CDJ52814.1 - 0.7 9.7 2.7 1.7 8.4 0.2 2.3 2 0 0 2 2 2 0 Fatty acid desaturase DUF4228 PF14009.6 CDJ52815.1 - 0.05 14.0 7.7 0.13 12.6 7.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) Trypan_PARP PF05887.11 CDJ52815.1 - 0.21 11.5 61.7 3 7.8 27.5 2.2 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) PA26 PF04636.13 CDJ52815.1 - 1.3 7.9 20.2 1.5 7.7 20.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Silic_transp PF03842.13 CDJ52815.1 - 1.3 7.2 5.7 1.6 6.9 5.7 1.1 1 0 0 1 1 1 0 Silicon transporter TP53IP5 PF15331.6 CDJ52815.1 - 5 7.2 20.3 7.2 6.7 20.3 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF966 PF06136.13 CDJ52815.1 - 7.4 6.2 24.8 9.2 5.9 24.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Velvet PF11754.8 CDJ52815.1 - 8.6 6.2 10.5 12 5.8 10.5 1.2 1 0 0 1 1 1 0 Velvet factor ALMT PF11744.8 CDJ52815.1 - 9.1 5.0 18.8 12 4.6 18.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TMEM51 PF15345.6 CDJ52818.1 - 1.7e-05 24.8 16.2 1.7e-05 24.8 16.2 1.9 3 0 0 3 3 3 1 Transmembrane protein 51 SR-25 PF10500.9 CDJ52818.1 - 0.0078 15.9 37.2 0.0071 16.0 34.8 2.1 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein Vfa1 PF08432.10 CDJ52818.1 - 0.033 14.5 15.4 0.051 13.9 15.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2434 PF10361.9 CDJ52818.1 - 0.14 11.2 1.0 0.22 10.5 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) eIF-3_zeta PF05091.12 CDJ52818.1 - 0.27 10.2 16.4 0.32 9.9 16.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PA26 PF04636.13 CDJ52818.1 - 0.32 9.8 10.7 0.44 9.4 10.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Herpes_glycop PF01528.16 CDJ52818.1 - 0.57 9.0 1.7 0.89 8.3 1.7 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Folate_carrier PF01770.18 CDJ52818.1 - 0.78 8.4 7.4 0.54 8.9 5.8 1.5 1 1 0 1 1 1 0 Reduced folate carrier Lin-8 PF03353.15 CDJ52818.1 - 1 8.8 24.9 2 7.9 4.9 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Afi1 PF07792.12 CDJ52818.1 - 1.1 9.7 12.1 0.25 11.8 6.4 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.22 CDJ52818.1 - 1.8 7.7 7.1 2.1 7.5 7.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S64 PF08192.11 CDJ52818.1 - 5.5 5.3 24.4 7.1 5.0 24.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 FHIPEP PF00771.20 CDJ52818.1 - 9.4 4.6 12.2 0.33 9.4 4.1 2.0 2 0 0 2 2 2 0 FHIPEP family Fumble PF03630.14 CDJ52819.1 - 7e-27 94.5 20.7 2.5e-23 82.8 0.7 4.4 1 1 2 3 3 3 2 Fumble DUF3801 PF12687.7 CDJ52819.1 - 1.2e-05 25.5 0.6 1.2e-05 25.5 0.6 3.2 3 1 0 3 3 3 2 Protein of unknown function (DUF3801) RskA PF10099.9 CDJ52819.1 - 0.00085 19.7 14.8 0.00085 19.7 14.8 6.1 4 2 1 5 5 5 1 Anti-sigma-K factor rskA ESM4 PF15952.5 CDJ52819.1 - 0.0012 19.3 41.3 0.31 11.4 24.1 3.4 3 0 0 3 3 3 3 Enhancer of split M4 family Androgen_recep PF02166.16 CDJ52819.1 - 0.0019 17.1 17.8 0.0019 17.1 17.8 7.6 4 3 0 7 7 7 1 Androgen receptor SUIM_assoc PF16619.5 CDJ52819.1 - 0.014 15.4 3.9 0.014 15.4 3.9 8.2 5 2 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 Nha1_C PF08619.10 CDJ52819.1 - 0.25 10.5 42.1 0.079 12.2 7.9 3.3 3 0 0 3 3 3 0 Alkali metal cation/H+ antiporter Nha1 C terminus TFIIA PF03153.13 CDJ52821.1 - 1.1 9.1 21.1 1.4 8.9 21.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM199X PF15814.5 CDJ52821.1 - 1.6 7.7 6.6 1.8 7.6 6.6 1.0 1 0 0 1 1 1 0 Protein family FAM199X XTBD PF11952.8 CDJ52822.1 - 2.6e-05 23.9 0.4 4.1e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 XRN-Two Binding Domain, XTBD Tic110 PF16940.5 CDJ52822.1 - 0.038 12.5 2.6 0.051 12.1 2.6 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter CDC14 PF08045.11 CDJ52823.1 - 0.017 14.2 0.2 0.038 13.1 0.2 1.5 1 0 0 1 1 1 0 Cell division control protein 14, SIN component TFIIA PF03153.13 CDJ52823.1 - 0.21 11.6 8.7 0.3 11.0 8.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ52823.1 - 0.65 8.6 11.5 0.9 8.2 11.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.8 CDJ52823.1 - 8.2 5.3 14.8 16 4.3 14.8 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Chromo PF00385.24 CDJ52824.1 - 1e-10 41.4 0.0 2.2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NTP_transf_3 PF12804.7 CDJ52826.1 - 1.1e-12 48.6 0.0 2.9e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 CDJ52826.1 - 8e-12 45.3 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 CDJ52826.1 - 0.0011 18.0 0.1 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 L-fucokinase Hexapep PF00132.24 CDJ52826.1 - 0.032 14.0 0.4 0.62 9.9 0.4 2.7 1 1 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) CTP_transf_3 PF02348.19 CDJ52826.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase DUF4954 PF16314.5 CDJ52826.1 - 0.17 10.0 0.1 0.25 9.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CTP_transf_like PF01467.26 CDJ52827.1 - 0.0055 16.9 0.0 0.25 11.5 0.0 3.0 3 1 0 3 3 3 1 Cytidylyltransferase-like FAD_syn PF06574.12 CDJ52827.1 - 0.049 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase UPF0184 PF03670.13 CDJ52828.1 - 0.013 15.9 2.0 0.04 14.3 0.1 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) TEX12 PF15219.6 CDJ52828.1 - 0.015 15.6 0.1 0.042 14.2 0.1 1.7 2 0 0 2 2 2 0 Testis-expressed 12 DUF812 PF05667.11 CDJ52828.1 - 0.032 13.1 1.5 0.055 12.4 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Topoisom_I PF01028.20 CDJ52828.1 - 0.034 13.4 1.0 0.051 12.8 1.0 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core Mononeg_RNA_pol PF00946.19 CDJ52828.1 - 0.22 9.1 0.1 0.31 8.6 0.1 1.1 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase IMPDH PF00478.25 CDJ52830.1 - 1.3e-125 419.0 6.5 1.9e-125 418.5 6.5 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CDJ52830.1 - 5.2e-11 42.8 0.1 0.00043 20.7 0.0 3.1 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 CDJ52830.1 - 8.5e-11 41.5 2.5 2e-10 40.3 1.3 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CDJ52830.1 - 3.7e-10 39.7 6.1 4.7e-07 29.5 4.7 2.7 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 CDJ52830.1 - 6.2e-06 25.8 2.6 5.4e-05 22.8 2.6 2.4 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 CDJ52830.1 - 0.00046 19.6 0.9 0.0009 18.6 0.9 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 CDJ52830.1 - 0.0012 18.1 1.1 0.42 9.8 0.1 2.8 1 1 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase G3P_antiterm PF04309.12 CDJ52830.1 - 0.041 13.3 0.5 0.62 9.5 0.1 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DHO_dh PF01180.21 CDJ52830.1 - 0.046 12.9 1.2 0.077 12.2 0.3 1.7 1 1 0 2 2 2 0 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 CDJ52830.1 - 0.062 12.6 2.4 0.19 11.1 1.5 2.2 2 1 0 2 2 2 0 Thiamine monophosphate synthase Glu_synthase PF01645.17 CDJ52830.1 - 0.078 12.1 3.1 0.11 11.6 2.0 1.7 2 0 0 2 2 2 0 Conserved region in glutamate synthase Exo_endo_phos PF03372.23 CDJ52831.1 - 1.9e-07 30.9 0.0 4.4e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 CDJ52832.1 - 1e-33 116.8 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ52832.1 - 1.8e-23 83.2 0.0 2.6e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ52832.1 - 0.029 14.3 0.1 0.064 13.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltrans_SAM PF10672.9 CDJ52834.1 - 8e-08 31.8 0.1 4.8e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 CDJ52834.1 - 7.6e-07 28.9 1.6 0.012 15.3 0.0 2.5 2 0 0 2 2 2 2 Conserved hypothetical protein 95 MTS PF05175.14 CDJ52834.1 - 8.5e-06 25.4 2.2 0.00045 19.8 0.2 2.4 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CDJ52834.1 - 0.003 17.3 0.0 3.8 7.3 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain UPF0020 PF01170.18 CDJ52834.1 - 0.0038 16.9 0.2 0.16 11.6 0.0 2.3 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 PUA_3 PF17785.1 CDJ52834.1 - 0.019 14.8 0.0 0.14 12.0 0.0 2.4 1 1 0 1 1 1 0 PUA-like domain Methyltransf_18 PF12847.7 CDJ52834.1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ52834.1 - 0.041 14.6 1.7 0.24 12.1 0.4 2.6 1 1 1 2 2 2 0 Methyltransferase domain N6-adenineMlase PF10237.9 CDJ52834.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase PrmA PF06325.13 CDJ52834.1 - 0.84 9.0 4.3 0.25 10.7 0.2 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) SLC12 PF03522.15 CDJ52835.1 - 0.082 11.9 16.1 0.098 11.7 16.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF2464 PF10240.9 CDJ52835.1 - 0.15 11.6 6.2 0.21 11.1 6.2 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 PA26 PF04636.13 CDJ52835.1 - 0.28 10.0 11.5 0.33 9.8 11.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Zip PF02535.22 CDJ52835.1 - 0.58 9.3 4.0 0.64 9.2 4.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HCO3_cotransp PF00955.21 CDJ52835.1 - 0.73 8.6 3.8 0.77 8.5 3.8 1.1 1 0 0 1 1 1 0 HCO3- transporter family Csm4_C PF17953.1 CDJ52835.1 - 1.7 8.5 5.0 0.28 11.1 0.8 1.8 2 0 0 2 2 2 0 CRISPR Csm4 C-terminal domain Presenilin PF01080.17 CDJ52835.1 - 1.8 7.3 22.9 2.2 7.0 22.9 1.1 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 CDJ52835.1 - 2.1 6.4 16.8 2.7 6.0 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 CDJ52835.1 - 3.9 6.3 8.7 5 6.0 8.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nha1_C PF08619.10 CDJ52835.1 - 6.5 5.8 26.0 9.8 5.3 26.0 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Neur_chan_memb PF02932.16 CDJ52835.1 - 8.5 6.4 15.7 11 6.0 15.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DSPc PF00782.20 CDJ52836.1 - 1.3e-08 34.7 0.0 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ52836.1 - 0.00032 20.3 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDJ52836.1 - 0.013 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate TFIIA PF03153.13 CDJ52837.1 - 0.059 13.4 18.3 0.064 13.2 18.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S66 PF02016.15 CDJ52837.1 - 0.13 12.3 0.4 0.24 11.5 0.4 1.4 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain OmpH PF03938.14 CDJ52837.1 - 0.17 12.2 18.5 0.25 11.7 18.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Itfg2 PF15907.5 CDJ52837.1 - 0.23 10.5 6.2 0.27 10.2 6.2 1.0 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 ALMT PF11744.8 CDJ52837.1 - 0.26 10.1 4.8 0.3 9.9 4.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Spt20 PF12090.8 CDJ52837.1 - 0.41 10.2 17.8 0.6 9.7 17.8 1.3 1 0 0 1 1 1 0 Spt20 family DUF4407 PF14362.6 CDJ52837.1 - 0.51 9.6 11.4 0.62 9.4 11.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2722 PF10846.8 CDJ52837.1 - 0.77 8.6 12.6 1.2 8.0 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Exonuc_VII_L PF02601.15 CDJ52837.1 - 1.3 8.5 10.5 1.5 8.3 10.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Activator_LAG-3 PF11498.8 CDJ52837.1 - 3.2 6.6 29.7 3.8 6.4 29.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Presenilin PF01080.17 CDJ52837.1 - 5.1 5.7 5.0 5.4 5.7 5.0 1.1 1 0 0 1 1 1 0 Presenilin FapA PF03961.13 CDJ52837.1 - 5.3 5.5 7.0 6.9 5.2 7.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DNA_pol_A_exo1 PF01612.20 CDJ52838.1 - 2.4e-09 37.1 0.1 6.2e-09 35.8 0.1 1.6 2 0 0 2 2 2 1 3'-5' exonuclease SPX PF03105.19 CDJ52838.1 - 4.1 7.2 11.4 0.28 11.1 3.1 2.6 3 0 0 3 3 3 0 SPX domain FAM60A PF15396.6 CDJ52839.1 - 0.13 12.3 15.0 0.16 12.0 15.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Cwf_Cwc_15 PF04889.12 CDJ52839.1 - 0.3 10.8 27.0 0.34 10.6 27.0 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4746 PF15928.5 CDJ52839.1 - 0.83 9.0 14.8 1 8.7 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Peptidase_S49_N PF08496.10 CDJ52839.1 - 0.86 9.6 21.1 1.3 9.1 21.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.12 CDJ52839.1 - 0.91 9.3 21.1 1.1 9.1 21.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Plasmodium_Vir PF05795.11 CDJ52839.1 - 0.99 8.8 7.5 1.2 8.5 7.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hydin_ADK PF17213.3 CDJ52839.1 - 0.99 9.6 16.4 1.2 9.4 16.4 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MRP-S31 PF15433.6 CDJ52839.1 - 1.3 8.6 23.3 1.6 8.3 23.3 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 CDC45 PF02724.14 CDJ52839.1 - 1.7 6.8 16.8 1.8 6.7 16.8 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 CDJ52839.1 - 1.8 7.3 16.1 2 7.1 16.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Sin_N PF04801.13 CDJ52839.1 - 2.3 7.4 33.5 2.4 7.3 33.5 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF872 PF05915.12 CDJ52839.1 - 2.6 8.2 4.4 0.65 10.2 1.0 1.7 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) PepSY_TM PF03929.16 CDJ52839.1 - 3.1 7.4 10.1 4.2 7.0 10.1 1.3 1 0 0 1 1 1 0 PepSY-associated TM region MMR1 PF08505.10 CDJ52839.1 - 3.7 7.8 26.5 4.1 7.6 26.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein NARP1 PF12569.8 CDJ52839.1 - 3.8 6.3 23.5 4.2 6.2 23.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SLC12 PF03522.15 CDJ52839.1 - 4.1 6.3 23.9 4.5 6.2 23.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Suf PF05843.14 CDJ52839.1 - 7.3 6.5 29.2 8.6 6.2 29.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RskA PF10099.9 CDJ52840.1 - 0.0032 17.8 12.3 0.0037 17.6 12.3 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA PhnG PF06754.12 CDJ52840.1 - 1.1 9.1 11.0 1.5 8.8 11.0 1.2 1 1 0 1 1 1 0 Phosphonate metabolism protein PhnG Presenilin PF01080.17 CDJ52840.1 - 9.1 4.9 8.1 11 4.7 8.1 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ52840.1 - 9.3 6.2 6.9 11 6.0 6.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ52841.1 - 2.4 6.8 30.2 2.8 6.6 30.2 1.0 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ52842.1 - 0.0025 16.9 30.5 0.0026 16.8 30.5 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2828 PF11443.8 CDJ52842.1 - 0.0097 14.0 22.5 0.01 14.0 22.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Nop53 PF07767.11 CDJ52842.1 - 0.011 15.2 34.9 0.011 15.2 34.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PAT1 PF09770.9 CDJ52842.1 - 0.012 13.9 37.9 0.012 13.9 37.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_11 PF13086.6 CDJ52842.1 - 0.066 13.0 26.0 0.074 12.8 26.0 1.2 1 0 0 1 1 1 0 AAA domain Med19 PF10278.9 CDJ52842.1 - 0.13 12.2 20.6 0.19 11.7 20.6 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SprA-related PF12118.8 CDJ52842.1 - 0.2 10.8 58.4 0.24 10.5 58.4 1.0 1 0 0 1 1 1 0 SprA-related family UPF0564 PF10595.9 CDJ52842.1 - 0.22 10.5 46.8 0.24 10.4 46.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 RR_TM4-6 PF06459.12 CDJ52842.1 - 0.27 11.0 35.8 0.39 10.5 35.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 CDJ52842.1 - 0.74 8.5 23.0 0.78 8.5 23.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AF-4 PF05110.13 CDJ52842.1 - 0.75 7.8 50.1 0.87 7.6 50.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PA26 PF04636.13 CDJ52842.1 - 1.7 7.5 24.0 1.9 7.3 24.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SID-1_RNA_chan PF13965.6 CDJ52842.1 - 2.2 6.6 15.4 2.2 6.6 15.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Paramyxo_ncap PF00973.19 CDJ52842.1 - 2.3 7.0 23.3 2.3 7.0 23.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ALMT PF11744.8 CDJ52842.1 - 2.9 6.6 26.6 3.8 6.2 26.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 CDJ52842.1 - 4.4 5.3 31.4 5.1 5.1 31.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAGA-Tad1 PF12767.7 CDJ52842.1 - 4.7 6.9 28.2 6.1 6.5 28.2 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Exonuc_VII_L PF02601.15 CDJ52842.1 - 5 6.6 29.9 6.1 6.3 29.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CDC45 PF02724.14 CDJ52842.1 - 5.8 5.1 33.7 7.2 4.8 33.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 CDJ52842.1 - 6.8 6.8 33.9 9.6 6.3 33.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SLC12 PF03522.15 CDJ52842.1 - 7.6 5.4 36.7 9.5 5.1 36.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RAP1 PF07218.11 CDJ52842.1 - 8.2 4.6 14.2 9.5 4.4 14.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cellulose_synt PF03552.14 CDJ52842.1 - 8.3 4.8 15.9 11 4.4 15.9 1.3 1 0 0 1 1 1 0 Cellulose synthase eIF3_subunit PF08597.10 CDJ52842.1 - 8.4 6.2 38.7 12 5.7 38.7 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CAC1F_C PF16885.5 CDJ52842.1 - 8.7 5.9 26.8 10 5.7 26.8 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term LRR_8 PF13855.6 CDJ52843.1 - 2.8e-06 27.0 34.0 0.011 15.4 4.7 4.6 4 1 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CDJ52843.1 - 8.5 7.0 42.5 0.2 12.1 4.6 6.3 5 2 0 6 6 6 0 Leucine Rich repeats (2 copies) cEGF PF12662.7 CDJ52844.1 - 0.00021 21.1 30.8 0.07 13.1 0.5 5.6 6 0 0 6 6 5 3 Complement Clr-like EGF-like DUF1645 PF07816.11 CDJ52844.1 - 0.0006 20.5 15.7 0.027 15.1 5.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1645) EGF PF00008.27 CDJ52844.1 - 0.00067 19.9 7.9 0.0072 16.6 2.4 5.7 6 0 0 6 6 4 4 EGF-like domain SR-25 PF10500.9 CDJ52844.1 - 0.00098 18.8 11.4 0.00098 18.8 11.4 3.1 3 0 0 3 3 2 2 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ52844.1 - 0.0034 16.3 9.4 0.005 15.7 9.4 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain FXa_inhibition PF14670.6 CDJ52844.1 - 0.0092 16.3 4.2 0.0092 16.3 4.2 5.5 5 1 0 5 5 5 2 Coagulation Factor Xa inhibitory site DUF755 PF05501.11 CDJ52844.1 - 0.0092 16.2 10.4 0.0092 16.2 10.4 3.3 2 1 0 2 2 1 1 Domain of unknown function (DUF755) EGF_MSP1_1 PF12946.7 CDJ52844.1 - 0.063 13.3 29.3 1.2 9.2 5.4 4.8 4 0 0 4 4 4 0 MSP1 EGF domain 1 ANAPC1 PF12859.7 CDJ52844.1 - 0.12 12.9 11.4 0.34 11.5 1.9 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 EGF_3 PF12947.7 CDJ52844.1 - 0.33 11.2 50.6 0.22 11.7 3.3 5.6 3 2 1 5 5 4 0 EGF domain EBP50_C PF09007.11 CDJ52844.1 - 0.37 11.8 14.2 2.7 9.0 3.7 2.4 2 0 0 2 2 2 0 EBP50, C-terminal Peroxin-3 PF04882.12 CDJ52844.1 - 0.43 9.5 8.8 0.68 8.9 8.8 1.2 1 0 0 1 1 1 0 Peroxin-3 Presenilin PF01080.17 CDJ52844.1 - 0.61 8.8 6.7 0.93 8.2 6.7 1.2 1 0 0 1 1 1 0 Presenilin Secretin_N_2 PF07655.13 CDJ52844.1 - 1.8 9.2 29.3 3.3 8.3 14.4 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain SPX PF03105.19 CDJ52844.1 - 2.1 8.1 19.2 0.016 15.2 9.7 1.8 2 0 0 2 2 2 0 SPX domain Chorion_2 PF03964.15 CDJ52844.1 - 2.8 8.8 24.2 0.38 11.6 2.3 3.4 3 0 0 3 3 3 0 Chorion family 2 Lin-8 PF03353.15 CDJ52844.1 - 3.1 7.3 13.4 0.64 9.5 4.4 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CCDC106 PF15794.5 CDJ52844.1 - 3.2 7.4 23.3 4.5 6.9 7.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Spt20 PF12090.8 CDJ52844.1 - 3.9 7.0 16.3 0.12 11.9 9.1 1.8 2 0 0 2 2 2 0 Spt20 family ANAPC_CDC26 PF10471.9 CDJ52844.1 - 6.3 7.7 18.9 0.079 13.8 7.8 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Pap_E4 PF02711.14 CDJ52844.1 - 9.3 7.3 12.8 1.7 9.7 1.8 2.9 2 0 0 2 2 2 0 E4 protein AF-4 PF05110.13 CDJ52844.1 - 9.7 4.1 38.7 1.4 6.9 12.5 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein LMBR1 PF04791.16 CDJ52847.1 - 0.019 13.9 6.8 0.021 13.7 6.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Telomerase_RBD PF12009.8 CDJ52847.1 - 0.045 13.9 0.1 0.13 12.4 0.1 1.8 1 1 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain Macoilin PF09726.9 CDJ52847.1 - 5.6 5.4 23.7 8.1 4.9 23.7 1.2 1 0 0 1 1 1 0 Macoilin family Ribosomal_L6e PF01159.19 CDJ52850.1 - 3.6e-34 117.6 0.2 5.2e-34 117.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e DUF2514 PF10721.9 CDJ52850.1 - 0.45 10.5 10.3 0.27 11.3 5.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) ANAPC4_WD40 PF12894.7 CDJ52853.1 - 6e-08 32.9 0.1 0.34 11.2 0.0 3.3 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ52853.1 - 0.0001 23.0 13.6 0.04 14.8 1.0 3.7 3 1 1 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CDJ52853.1 - 0.005 15.8 0.1 0.0095 14.9 0.1 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coilin_N PF15862.5 CDJ52855.1 - 0.1 12.4 0.0 0.1 12.4 0.0 5.4 3 2 3 6 6 6 0 Coilin N-terminus Bcl-2_BAD PF10514.9 CDJ52856.1 - 4 7.9 17.3 4.9 7.6 17.3 1.2 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD TFIIA PF03153.13 CDJ52857.1 - 0.011 15.8 24.0 0.013 15.5 24.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ52857.1 - 0.12 11.1 2.6 0.12 11.1 2.6 1.1 1 0 0 1 1 1 0 Presenilin MCU PF04678.13 CDJ52857.1 - 0.14 12.3 2.9 0.18 11.9 2.9 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Suf PF05843.14 CDJ52857.1 - 0.17 11.8 9.6 0.2 11.6 9.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2722 PF10846.8 CDJ52857.1 - 0.41 9.5 16.1 0.61 9.0 16.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Neur_chan_memb PF02932.16 CDJ52857.1 - 0.43 10.6 0.8 0.46 10.5 0.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1467 PF07330.12 CDJ52857.1 - 0.45 10.5 0.1 0.45 10.5 0.1 2.2 2 1 0 2 2 1 0 Protein of unknown function (DUF1467) DUF3464 PF11947.8 CDJ52857.1 - 0.96 9.2 4.3 1.6 8.5 4.3 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2232 PF09991.9 CDJ52857.1 - 1 8.5 2.5 1.3 8.2 2.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF2992 PF11208.8 CDJ52857.1 - 2 8.7 12.5 2.7 8.2 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) TERB2 PF15101.6 CDJ52857.1 - 2.1 8.3 8.2 2.9 7.9 8.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PAT1 PF09770.9 CDJ52857.1 - 2.6 6.2 17.0 3.1 6.0 17.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0560 PF10577.9 CDJ52857.1 - 3.4 6.0 10.1 4.1 5.8 10.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Rpp20 PF12328.8 CDJ52857.1 - 5.6 6.9 6.9 7.8 6.5 6.9 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Activator_LAG-3 PF11498.8 CDJ52857.1 - 9.9 5.0 32.0 13 4.6 32.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pex14_N PF04695.13 CDJ52859.1 - 0.0022 18.7 13.7 0.0028 18.3 13.7 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ52859.1 - 0.0084 16.2 9.7 0.0084 16.2 9.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PRIMA1 PF16101.5 CDJ52859.1 - 0.024 14.7 6.9 0.031 14.3 6.9 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PRR18 PF15671.5 CDJ52859.1 - 0.059 13.3 7.2 0.061 13.2 7.2 1.1 1 0 0 1 1 1 0 Proline-rich protein family 18 MGC-24 PF05283.11 CDJ52859.1 - 0.11 12.9 2.7 0.12 12.8 2.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Trypan_PARP PF05887.11 CDJ52859.1 - 0.12 12.3 11.1 0.16 11.9 11.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2722 PF10846.8 CDJ52859.1 - 0.2 10.5 9.1 0.22 10.4 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SOG2 PF10428.9 CDJ52859.1 - 0.21 10.8 4.4 0.2 10.8 4.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4698 PF15769.5 CDJ52859.1 - 0.23 10.5 2.9 0.23 10.5 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) BRF1 PF07741.13 CDJ52859.1 - 0.65 10.4 4.1 0.87 10.0 4.1 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Sporozoite_P67 PF05642.11 CDJ52859.1 - 0.7 7.9 5.1 0.75 7.8 5.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4366 PF14283.6 CDJ52859.1 - 0.71 9.9 5.9 0.94 9.5 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Spt20 PF12090.8 CDJ52859.1 - 0.72 9.4 15.3 0.84 9.2 15.3 1.1 1 0 0 1 1 1 0 Spt20 family RIFIN PF02009.16 CDJ52859.1 - 0.77 9.6 2.7 0.93 9.3 2.7 1.2 1 0 0 1 1 1 0 Rifin Ndc1_Nup PF09531.10 CDJ52859.1 - 0.97 8.0 5.7 0.91 8.1 5.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BAT2_N PF07001.11 CDJ52859.1 - 1.4 9.3 14.1 1.9 8.9 14.1 1.2 1 0 0 1 1 1 0 BAT2 N-terminus DUF1180 PF06679.12 CDJ52859.1 - 2.1 8.7 8.8 2.4 8.6 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Mito_fiss_reg PF05308.11 CDJ52859.1 - 2.7 8.0 10.1 3.1 7.8 10.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF935 PF06074.12 CDJ52859.1 - 2.9 6.5 7.4 3.1 6.4 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Mitofilin PF09731.9 CDJ52859.1 - 4.8 5.9 13.5 5.3 5.8 13.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CPSF100_C PF13299.6 CDJ52859.1 - 8.5 6.5 6.5 11 6.2 6.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Mucin PF01456.17 CDJ52859.1 - 9 6.3 21.4 13 5.8 21.4 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein Oleosin PF01277.17 CDJ52860.1 - 0.0034 17.1 14.1 0.0057 16.4 13.8 1.5 1 1 0 1 1 1 1 Oleosin DEC-1_N PF04625.13 CDJ52860.1 - 0.21 10.5 17.9 0.23 10.4 17.9 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region THOC2_N PF16134.5 CDJ52860.1 - 0.39 9.3 4.8 0.59 8.7 4.8 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Activator_LAG-3 PF11498.8 CDJ52860.1 - 0.56 9.1 18.8 0.71 8.8 18.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ52860.1 - 1.2 9.1 20.0 1.4 8.9 20.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CytochromB561_N PF09786.9 CDJ52860.1 - 1.6 7.6 5.4 2.2 7.2 5.4 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Myc_N PF01056.18 CDJ52860.1 - 3.1 7.6 6.5 3.6 7.4 6.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Orf78 PF06024.12 CDJ52860.1 - 4.6 7.6 6.5 0.74 10.1 0.3 2.2 2 1 0 2 2 2 0 Orf78 (ac78) Miga PF10265.9 CDJ52861.1 - 0.036 13.1 23.6 0.04 12.9 23.6 1.0 1 0 0 1 1 1 0 Mitoguardin TFIIA PF03153.13 CDJ52861.1 - 1.2 9.0 26.6 1.5 8.7 26.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.13 CDJ52861.1 - 5.6 5.4 21.8 6.6 5.2 21.8 1.0 1 0 0 1 1 1 0 Utp14 protein Spt20 PF12090.8 CDJ52862.1 - 4.8e-05 23.1 25.1 0.012 15.2 12.6 2.1 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ52862.1 - 0.00084 18.4 22.6 0.034 13.1 1.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) DUF4658 PF15555.6 CDJ52862.1 - 0.08 13.1 0.1 0.08 13.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Shadoo PF14999.6 CDJ52862.1 - 0.19 11.8 8.4 0.31 11.1 8.4 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Lin-8 PF03353.15 CDJ52862.1 - 0.24 10.9 13.2 0.35 10.4 7.5 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Protamine_P2 PF00841.19 CDJ52862.1 - 0.62 10.6 15.0 1.1 9.7 6.9 2.2 2 0 0 2 2 2 0 Sperm histone P2 DUF702 PF05142.12 CDJ52862.1 - 1.8 9.0 12.9 3.3 8.2 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF4667 PF15700.5 CDJ52862.1 - 7.2 6.6 21.3 2.2 8.3 11.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ52862.1 - 8 6.0 20.7 0.53 9.8 13.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Caldesmon PF02029.15 CDJ52863.1 - 0.2 10.4 71.4 0.22 10.3 71.4 1.0 1 0 0 1 1 1 0 Caldesmon SDA1 PF05285.12 CDJ52863.1 - 7 6.0 71.3 0.27 10.6 46.7 2.1 2 0 0 2 2 2 0 SDA1 eIF3_subunit PF08597.10 CDJ52864.1 - 0.16 11.9 25.1 0.19 11.6 25.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit AUX_IAA PF02309.16 CDJ52864.1 - 1.3 8.8 4.2 1.9 8.3 4.2 1.2 1 0 0 1 1 1 0 AUX/IAA family Presenilin PF01080.17 CDJ52864.1 - 1.6 7.4 7.1 2.2 7.0 7.1 1.1 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 CDJ52864.1 - 1.7 7.9 18.7 2 7.7 18.7 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CDJ52864.1 - 2.3 6.3 17.5 2.8 6.0 17.5 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 CDJ52864.1 - 3.4 6.4 5.5 3.6 6.3 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.6 CDJ52864.1 - 3.5 6.3 6.1 4.1 6.0 6.1 1.1 1 0 0 1 1 1 0 Raftlin DUF2868 PF11067.8 CDJ52864.1 - 3.9 6.9 13.2 4.9 6.6 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Tim54 PF11711.8 CDJ52864.1 - 4.1 6.1 6.5 5.3 5.7 6.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4045 PF13254.6 CDJ52864.1 - 5.1 6.6 8.9 6.1 6.4 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Dsh_C PF12316.8 CDJ52864.1 - 5.7 7.3 8.9 8.8 6.7 8.9 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DNA_pol_phi PF04931.13 CDJ52864.1 - 5.8 4.9 17.2 7.2 4.6 17.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DER1 PF04511.15 CDJ52865.1 - 8.2e-21 74.8 0.1 1.9e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 Der1-like family Hid1 PF12722.7 CDJ52865.1 - 0.015 13.5 9.9 0.017 13.3 9.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 CDJ52865.1 - 0.053 11.8 13.9 0.087 11.1 13.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ52865.1 - 0.76 8.5 24.9 0.15 10.8 20.6 1.8 2 0 0 2 2 2 0 Presenilin GREB1 PF15782.5 CDJ52865.1 - 1.2 6.1 14.2 1.4 6.0 14.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 CDJ52865.1 - 1.8 8.3 22.9 2.7 7.8 22.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CLN3 PF02487.17 CDJ52865.1 - 2.6 7.0 13.8 5.6 5.9 13.8 1.5 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 CDJ52865.1 - 5.8 5.6 13.8 8.8 5.0 13.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter LCD1 PF09798.9 CDJ52865.1 - 7.8 4.9 14.6 9.8 4.6 14.6 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein XRN_M PF17846.1 CDJ52865.1 - 8.2 5.3 16.4 12 4.7 16.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Sec62 PF03839.16 CDJ52865.1 - 8.3 5.9 17.2 15 5.0 17.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 RskA PF10099.9 CDJ52866.1 - 0.018 15.3 0.1 0.018 15.3 0.1 9.0 2 2 4 6 6 6 0 Anti-sigma-K factor rskA FBPase PF00316.20 CDJ52868.1 - 1.1e-66 224.0 0.0 1.4e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NdhM PF10664.9 CDJ52868.1 - 0.099 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Proteasome PF00227.26 CDJ52869.1 - 9.2e-37 126.4 2.6 9.2e-37 126.4 2.6 2.5 2 1 0 2 2 2 1 Proteasome subunit LMBR1 PF04791.16 CDJ52869.1 - 0.31 9.9 0.0 0.43 9.4 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2722 PF10846.8 CDJ52870.1 - 6.2e-05 22.1 1.0 6.2e-05 22.1 1.0 6.4 6 0 0 6 6 6 4 Protein of unknown function (DUF2722) Pkinase PF00069.25 CDJ52870.1 - 0.0018 17.7 0.1 0.0018 17.7 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ52870.1 - 0.0071 15.7 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Myc_N PF01056.18 CDJ52870.1 - 0.037 13.9 0.0 0.037 13.9 0.0 6.3 7 1 1 8 8 8 0 Myc amino-terminal region Spt20 PF12090.8 CDJ52870.1 - 0.098 12.2 111.2 0.093 12.3 4.4 6.4 6 0 0 6 6 6 0 Spt20 family rve PF00665.26 CDJ52871.1 - 3e-10 40.3 0.4 9.5e-10 38.7 0.1 2.0 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.11 CDJ52871.1 - 7.9e-08 32.2 0.4 4.3e-07 29.8 0.0 2.2 3 0 0 3 3 3 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ52871.1 - 2.9e-07 31.0 0.0 6.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ52871.1 - 1.4e-06 28.7 0.0 2.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 CDJ52871.1 - 0.0081 16.0 0.2 0.018 15.0 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.20 CDJ52871.1 - 0.038 14.3 0.0 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 CDJ52871.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease MOZ_SAS PF01853.18 CDJ52872.1 - 1.9e-44 151.5 0.0 1.6e-43 148.4 0.0 2.0 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CDJ52872.1 - 6e-16 57.8 0.0 1.1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDJ52872.1 - 2.4e-10 40.2 0.1 1.3e-09 37.8 0.1 2.1 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CDJ52872.1 - 0.012 16.1 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Chromo PF00385.24 CDJ52873.1 - 0.00022 21.1 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_L23 PF00276.20 CDJ52874.1 - 1.2e-12 48.0 0.0 2.5e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 FluMu_N PF17891.1 CDJ52874.1 - 0.0015 18.3 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Mu-like prophage FluMu N-terminal domain TFIIA PF03153.13 CDJ52875.1 - 0.0023 18.0 14.3 0.0023 18.0 14.3 5.6 2 1 2 5 5 5 1 Transcription factor IIA, alpha/beta subunit Peptidase_C97 PF05903.14 CDJ52876.1 - 2.8e-21 75.9 0.0 4.6e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF2722 PF10846.8 CDJ52877.1 - 1e-05 24.7 3.8 1.1e-05 24.6 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ52877.1 - 0.015 15.3 11.7 0.017 15.1 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ52877.1 - 0.019 15.7 10.0 0.025 15.2 10.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spore_coat_CotO PF14153.6 CDJ52877.1 - 0.032 14.2 6.0 0.037 13.9 6.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Suf PF05843.14 CDJ52877.1 - 0.092 12.7 5.2 0.1 12.6 5.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ52877.1 - 0.12 12.0 19.0 0.19 11.3 19.0 1.3 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ52877.1 - 0.42 9.3 2.2 0.47 9.2 2.2 1.1 1 0 0 1 1 1 0 Presenilin ERF PF04404.12 CDJ52877.1 - 0.97 9.3 6.7 1.4 8.8 6.7 1.1 1 0 0 1 1 1 0 ERF superfamily DUF3464 PF11947.8 CDJ52877.1 - 2.2 8.0 5.1 3 7.6 5.1 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4834 PF16118.5 CDJ52877.1 - 3.5 8.6 5.9 4.9 8.2 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Coilin_N PF15862.5 CDJ52877.1 - 5.1 6.9 8.3 7.3 6.4 8.3 1.2 1 0 0 1 1 1 0 Coilin N-terminus DUF4407 PF14362.6 CDJ52877.1 - 7.1 5.9 7.8 9.4 5.5 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Roughex PF06020.11 CDJ52877.1 - 8.2 5.4 10.8 9.8 5.2 10.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Ribosomal_60s PF00428.19 CDJ52877.1 - 9.5 6.9 9.4 1.3 9.7 4.9 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein IMUP PF15761.5 CDJ52880.1 - 0.025 15.3 5.8 0.025 15.3 5.8 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein YfhO PF09586.10 CDJ52880.1 - 2.7 6.1 16.2 3.4 5.8 16.2 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RAP1 PF07218.11 CDJ52880.1 - 4.1 5.6 4.6 5.7 5.1 4.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Neur_chan_memb PF02932.16 CDJ52881.1 - 0.004 17.2 9.8 0.005 16.9 9.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Vac7 PF12751.7 CDJ52881.1 - 0.028 13.9 12.4 0.036 13.5 12.4 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Activator_LAG-3 PF11498.8 CDJ52881.1 - 0.034 13.1 76.5 0.047 12.7 76.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 NPR3 PF03666.13 CDJ52881.1 - 0.45 9.3 21.8 0.55 8.9 21.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 CDJ52881.1 - 0.63 10.0 19.8 1 9.3 19.8 1.4 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.9 CDJ52881.1 - 0.79 7.9 40.5 0.92 7.7 40.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.15 CDJ52881.1 - 0.8 9.2 30.4 1 8.8 30.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit RR_TM4-6 PF06459.12 CDJ52881.1 - 0.87 9.4 26.1 1.4 8.6 26.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med15 PF09606.10 CDJ52881.1 - 0.95 8.1 61.5 1.2 7.8 61.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MTBP_C PF14920.6 CDJ52881.1 - 1.1 8.9 23.4 2.3 7.9 23.0 1.6 2 0 0 2 2 2 0 MDM2-binding Draxin PF15550.6 CDJ52881.1 - 1.3 8.8 18.3 1.9 8.3 18.3 1.2 1 0 0 1 1 1 0 Draxin DUF2052 PF09747.9 CDJ52881.1 - 2.7 8.1 26.7 4 7.5 26.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FapA PF03961.13 CDJ52881.1 - 2.9 6.4 14.5 4.9 5.7 14.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A CDC45 PF02724.14 CDJ52881.1 - 6.3 5.0 23.6 8.3 4.6 23.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4045 PF13254.6 CDJ52881.1 - 7.7 6.1 25.9 10 5.6 25.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF572 PF04502.13 CDJ52881.1 - 7.9 6.0 25.3 13 5.3 25.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) ALMT PF11744.8 CDJ52881.1 - 9.3 4.9 22.2 12 4.6 22.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 CDJ52882.1 - 0.0094 16.0 23.2 0.0094 16.0 23.2 1.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit TFB6 PF17110.5 CDJ52882.1 - 0.01 15.6 3.1 0.013 15.2 3.1 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Hid1 PF12722.7 CDJ52882.1 - 0.011 14.0 3.5 0.01 14.0 3.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3824 PF12868.7 CDJ52882.1 - 0.022 15.4 8.6 0.022 15.4 8.6 3.4 3 1 0 3 3 1 0 Domain of unknwon function (DUF3824) V_ATPase_I PF01496.19 CDJ52882.1 - 0.086 10.7 7.4 0.098 10.6 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 CDJ52882.1 - 0.14 11.1 5.8 0.16 10.9 5.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_23 PF13476.6 CDJ52882.1 - 0.15 12.6 11.5 0.18 12.3 11.5 1.2 1 0 0 1 1 1 0 AAA domain FancD2 PF14631.6 CDJ52882.1 - 0.15 9.4 8.9 0.19 9.1 8.9 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Roughex PF06020.11 CDJ52882.1 - 0.19 10.8 17.1 0.31 10.1 17.1 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF778 PF05608.12 CDJ52882.1 - 0.3 11.4 3.3 0.36 11.2 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) DDHD PF02862.17 CDJ52882.1 - 0.44 10.7 11.5 0.58 10.3 11.5 1.2 1 0 0 1 1 1 0 DDHD domain Spt20 PF12090.8 CDJ52882.1 - 0.5 9.9 25.1 0.63 9.6 25.1 1.3 1 0 0 1 1 1 0 Spt20 family PA26 PF04636.13 CDJ52882.1 - 0.53 9.1 7.7 0.57 9.0 7.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MRP-S27 PF10037.9 CDJ52882.1 - 0.84 8.4 13.3 0.9 8.3 13.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 EOS1 PF12326.8 CDJ52882.1 - 0.91 9.4 3.7 1.4 8.8 3.7 1.3 1 0 0 1 1 1 0 N-glycosylation protein ORC_WH_C PF18137.1 CDJ52882.1 - 1.1 9.3 14.0 13 5.9 14.0 2.0 1 1 0 1 1 1 0 Origin recognition complex winged helix C-terminal CSG2 PF16965.5 CDJ52882.1 - 1.3 7.9 4.4 1.5 7.7 4.4 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DnaJ-X PF14308.6 CDJ52882.1 - 2.5 7.5 13.7 3.8 6.9 13.7 1.3 1 0 0 1 1 1 0 X-domain of DnaJ-containing FAM176 PF14851.6 CDJ52882.1 - 2.6 7.7 12.0 5.2 6.7 12.0 1.5 1 0 0 1 1 1 0 FAM176 family Connexin PF00029.19 CDJ52882.1 - 2.8 7.7 9.2 3.8 7.2 9.2 1.3 1 0 0 1 1 1 0 Connexin DUF1682 PF07946.14 CDJ52882.1 - 3.5 6.8 14.6 5.3 6.2 14.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4778 PF16008.5 CDJ52882.1 - 3.9 7.5 12.5 4.8 7.2 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) SpoIIP PF07454.11 CDJ52882.1 - 4.3 6.7 14.8 5.3 6.4 14.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TERB2 PF15101.6 CDJ52882.1 - 4.7 7.2 15.3 6 6.9 15.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Paf1 PF03985.13 CDJ52882.1 - 5.3 5.9 18.6 6.5 5.6 18.6 1.1 1 0 0 1 1 1 0 Paf1 Neur_chan_memb PF02932.16 CDJ52882.1 - 8.1 6.4 9.7 0.87 9.6 5.3 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ52882.1 - 8.9 5.0 21.6 0.39 9.4 15.7 1.7 2 0 0 2 2 2 0 Presenilin Ras PF00071.22 CDJ52884.1 - 1.7e-44 151.3 0.0 2.9e-44 150.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ52884.1 - 2.4e-32 111.6 0.0 5.3e-32 110.5 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ52884.1 - 3.9e-12 46.0 0.0 9.1e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ52884.1 - 5e-08 33.0 0.2 1.9e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ52884.1 - 4.8e-05 23.0 0.1 0.0033 17.0 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDJ52884.1 - 7.3e-05 22.2 0.1 0.00022 20.7 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ52884.1 - 0.0011 18.5 0.5 0.0021 17.5 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDJ52884.1 - 0.015 14.5 0.4 0.05 12.8 0.4 2.0 1 1 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 CDJ52884.1 - 0.024 14.1 2.6 0.066 12.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Septin PF00735.18 CDJ52884.1 - 0.045 13.0 0.1 0.045 13.0 0.1 1.7 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 CDJ52884.1 - 0.073 13.0 1.7 0.27 11.1 0.1 2.4 2 1 0 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 CDJ52884.1 - 0.28 11.1 1.4 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea CENP-T_C PF15511.6 CDJ52884.1 - 0.38 10.9 6.9 0.97 9.6 3.6 2.8 1 1 2 3 3 3 0 Centromere kinetochore component CENP-T histone fold Vir_act_alpha_C PF10400.9 CDJ52884.1 - 7.6 7.3 9.2 40 5.0 9.2 2.2 1 1 0 1 1 1 0 Virulence activator alpha C-term AAA_16 PF13191.6 CDJ52884.1 - 8.3 6.8 10.0 4.6e+02 1.1 10.0 2.6 1 1 0 1 1 1 0 AAA ATPase domain BAF1_ABF1 PF04684.13 CDJ52886.1 - 0.09 11.8 8.9 0.13 11.3 4.3 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor GMC_oxred_N PF00732.19 CDJ52887.1 - 2.6e-20 73.0 0.2 3.2e-10 39.9 0.0 2.5 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 CDJ52887.1 - 1.9e-19 70.6 0.8 1.9e-14 54.4 0.0 3.4 4 0 0 4 4 3 2 GMC oxidoreductase NAD_binding_8 PF13450.6 CDJ52887.1 - 2.3e-06 27.7 0.7 6.6e-06 26.3 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDJ52887.1 - 2.9e-05 23.3 1.6 6.3e-05 22.2 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CDJ52887.1 - 0.0001 21.7 0.1 0.0001 21.7 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CDJ52887.1 - 0.00021 21.0 0.4 0.00048 19.8 0.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDJ52887.1 - 0.00037 19.8 0.5 0.00096 18.5 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ52887.1 - 0.00042 19.2 0.2 0.00042 19.2 0.2 1.5 2 0 0 2 2 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 CDJ52887.1 - 0.0009 18.6 0.2 0.0026 17.1 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4647 PF15504.6 CDJ52887.1 - 0.0013 17.9 3.1 0.002 17.3 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4647) GDI PF00996.18 CDJ52887.1 - 0.0023 16.5 0.0 0.004 15.7 0.0 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor GIDA PF01134.22 CDJ52887.1 - 0.0026 16.9 1.2 0.0049 16.0 1.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CDJ52887.1 - 0.0041 17.6 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ52887.1 - 0.0064 15.9 0.9 0.0064 15.9 0.9 2.4 3 0 0 3 3 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDJ52887.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 CDJ52887.1 - 0.023 13.7 0.8 0.049 12.7 0.3 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 CDJ52887.1 - 0.15 12.1 0.0 9.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 CDJ52887.1 - 0.15 10.9 0.3 1 8.1 0.4 2.0 2 0 0 2 2 2 0 Tryptophan halogenase DUF2722 PF10846.8 CDJ52887.1 - 0.19 10.6 10.3 0.29 10.0 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ52887.1 - 0.45 10.5 13.9 1 9.3 13.9 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ52887.1 - 2.9 8.5 14.7 3.8 8.2 11.1 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LIM_bind PF01803.16 CDJ52887.1 - 3.2 7.2 5.8 5.7 6.4 5.8 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Spt20 PF12090.8 CDJ52887.1 - 3.4 7.2 17.8 5.5 6.5 17.8 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ52887.1 - 4.9 7.0 7.7 8.3 6.3 7.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM199X PF15814.5 CDJ52889.1 - 0.006 15.7 12.1 0.0073 15.4 12.1 1.1 1 0 0 1 1 1 1 Protein family FAM199X TFIIA PF03153.13 CDJ52889.1 - 0.11 12.5 23.1 0.11 12.4 23.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ52889.1 - 9.5 5.1 16.8 11 5.0 16.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GREB1 PF15782.5 CDJ52889.1 - 9.7 3.2 10.4 9.6 3.2 10.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MOFRL PF05161.13 CDJ52890.1 - 0.011 15.9 1.0 0.045 14.0 1.0 2.0 1 0 0 1 1 1 0 MOFRL family Joubert PF15392.6 CDJ52890.1 - 0.86 9.3 14.3 1.4 8.6 7.4 2.2 2 0 0 2 2 2 0 Joubert syndrome-associated PAT1 PF09770.9 CDJ52890.1 - 7.9 4.6 41.0 2.4 6.3 3.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Ribosomal_L22 PF00237.19 CDJ52891.1 - 3.5e-19 68.9 0.1 4.5e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e FAM25 PF15825.5 CDJ52892.1 - 0.36 11.2 7.7 0.93 9.9 1.9 2.7 2 1 0 2 2 2 0 FAM25 family UBX PF00789.20 CDJ52894.1 - 1e-09 38.5 0.3 3.4e-09 36.8 0.1 1.8 1 1 1 2 2 2 1 UBX domain UIM PF02809.20 CDJ52894.1 - 0.17 11.9 0.5 0.17 11.9 0.5 1.9 2 0 0 2 2 2 0 Ubiquitin interaction motif BUD22 PF09073.10 CDJ52895.1 - 3.5e-05 23.3 0.2 3.5e-05 23.3 0.2 6.0 3 2 2 5 5 5 2 BUD22 RskA PF10099.9 CDJ52899.1 - 6e-06 26.7 0.6 7e-05 23.2 0.2 23.0 5 4 13 18 18 18 5 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ52899.1 - 0.00021 20.7 3.5 0.00021 20.7 3.5 10.9 7 3 2 9 9 9 1 Sin-like protein conserved region SR-25 PF10500.9 CDJ52899.1 - 0.0024 17.5 2.3 0.0024 17.5 2.3 17.8 15 6 3 18 18 18 2 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 CDJ52899.1 - 0.01 15.2 0.0 0.01 15.2 0.0 8.7 7 3 1 8 8 8 0 BUD22 DUF4757 PF15949.5 CDJ52899.1 - 0.13 12.7 0.0 0.13 12.7 0.0 11.6 8 2 5 13 13 13 0 Domain of unknown function (DUF4757) Mito_carr PF00153.27 CDJ52899.1 - 0.73 9.8 6.5 2.6 8.0 0.1 5.6 3 0 0 3 3 3 0 Mitochondrial carrier protein DnaJ PF00226.31 CDJ52900.1 - 1.6e-16 60.2 0.1 2.6e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.6 CDJ52900.1 - 0.033 14.5 0.1 7.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Menin PF05053.13 CDJ52900.1 - 0.052 11.9 3.9 0.059 11.7 3.9 1.0 1 0 0 1 1 1 0 Menin SOG2 PF10428.9 CDJ52900.1 - 0.064 12.4 2.3 0.066 12.4 2.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TPR_2 PF07719.17 CDJ52900.1 - 0.15 12.2 0.1 0.15 12.2 0.1 3.4 3 2 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 CDJ52900.1 - 2 8.7 7.0 0.31 11.3 0.9 2.5 2 1 0 2 2 2 0 HemY protein N-terminus SR-25 PF10500.9 CDJ52901.1 - 1.4 8.5 45.5 0.27 10.8 21.4 2.3 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ52902.1 - 1.9e-05 24.9 50.4 2.3e-05 24.6 50.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Calsarcin PF05556.11 CDJ52902.1 - 6.9e-05 22.5 2.1 6.9e-05 22.5 2.1 2.3 1 1 1 2 2 2 1 Calcineurin-binding protein (Calsarcin) RskA PF10099.9 CDJ52902.1 - 0.0008 19.8 26.5 0.0019 18.5 26.5 1.7 1 1 0 1 1 1 1 Anti-sigma-K factor rskA Shadoo PF14999.6 CDJ52902.1 - 0.68 10.0 17.0 0.22 11.6 13.6 1.9 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective FAM199X PF15814.5 CDJ52902.1 - 3 6.8 14.1 6.1 5.8 14.1 1.6 1 0 0 1 1 1 0 Protein family FAM199X LMF1 PF06762.14 CDJ52903.1 - 1.3e-08 34.4 0.0 6.3e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 Lipase maturation factor DUF2063 PF09836.9 CDJ52903.1 - 0.0084 16.3 0.4 0.016 15.4 0.4 1.4 1 0 0 1 1 1 1 Putative DNA-binding domain Spt20 PF12090.8 CDJ52903.1 - 0.82 9.2 8.4 1.2 8.7 8.4 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ52903.1 - 6.2 5.6 9.9 9.5 4.9 9.9 1.2 1 0 0 1 1 1 0 Androgen receptor Fringe PF02434.16 CDJ52906.1 - 2.3e-18 66.6 0.0 4.8e-08 32.7 0.0 3.4 3 0 0 3 3 3 3 Fringe-like PRR18 PF15671.5 CDJ52907.1 - 0.0065 16.4 2.4 0.011 15.7 2.4 1.4 1 0 0 1 1 1 1 Proline-rich protein family 18 PRP1_N PF06424.12 CDJ52907.1 - 0.04 14.3 24.5 0.024 15.0 14.9 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal CCSAP PF15748.5 CDJ52907.1 - 0.11 12.6 32.1 0.16 12.1 22.9 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ52907.1 - 0.18 11.6 31.9 0.5 10.1 24.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 CDJ52907.1 - 0.22 10.9 30.7 1.4 8.3 1.0 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CobT PF06213.12 CDJ52907.1 - 0.48 9.8 45.8 0.2 11.0 31.2 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SLC12 PF03522.15 CDJ52907.1 - 0.54 9.2 30.1 1.8 7.5 24.2 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 CDJ52907.1 - 1.3 9.1 23.6 4.3 7.4 18.0 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Band_3_cyto PF07565.13 CDJ52907.1 - 1.6 8.4 30.4 4.1 7.1 0.7 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CSG2 PF16965.5 CDJ52907.1 - 1.7 7.5 15.2 0.26 10.2 8.1 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator Zip PF02535.22 CDJ52907.1 - 1.9 7.6 15.1 0.19 10.9 8.7 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter O-antigen_lig PF13425.6 CDJ52907.1 - 2 7.1 18.5 2.8 6.6 12.9 2.0 2 0 0 2 2 2 0 O-antigen ligase like membrane protein TRAP_alpha PF03896.16 CDJ52907.1 - 2 7.5 16.3 0.87 8.7 11.6 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_S49_N PF08496.10 CDJ52907.1 - 2.2 8.4 29.0 5.3 7.1 21.8 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal NPR3 PF03666.13 CDJ52907.1 - 2.6 6.7 28.2 0.67 8.7 21.4 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2828 PF11443.8 CDJ52907.1 - 2.8 5.9 30.9 5.4 5.0 25.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) V_ATPase_I PF01496.19 CDJ52907.1 - 3.4 5.5 31.5 2.7 5.8 23.8 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 CDJ52907.1 - 5.2 5.2 30.0 5.2 5.2 22.9 2.0 2 0 0 2 2 2 0 CDC45-like protein BORG_CEP PF14957.6 CDJ52907.1 - 5.4 8.2 24.9 14 6.8 0.4 2.1 2 0 0 2 2 2 0 Cdc42 effector PNISR PF15996.5 CDJ52907.1 - 7.3 6.8 40.1 8.3 6.6 29.5 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DUF913 PF06025.12 CDJ52909.1 - 3.6e-05 22.9 0.5 5.6e-05 22.3 0.5 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) CLN3 PF02487.17 CDJ52909.1 - 0.064 12.3 2.6 0.089 11.8 2.6 1.3 1 0 0 1 1 1 0 CLN3 protein RR_TM4-6 PF06459.12 CDJ52909.1 - 0.065 13.0 4.6 0.11 12.2 4.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CDJ52909.1 - 0.18 12.0 5.1 0.3 11.2 5.1 1.4 1 0 0 1 1 1 0 DDHD domain DUF775 PF05603.12 CDJ52909.1 - 0.28 10.7 11.4 0.029 13.9 6.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Exonuc_VII_L PF02601.15 CDJ52909.1 - 0.29 10.7 10.4 0.42 10.1 10.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 CDJ52909.1 - 0.78 7.6 8.4 1 7.2 8.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pex14_N PF04695.13 CDJ52909.1 - 0.79 10.4 17.7 0.14 12.8 12.7 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2828 PF11443.8 CDJ52909.1 - 0.87 7.6 7.1 1.2 7.2 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) ALMT PF11744.8 CDJ52909.1 - 0.89 8.3 3.0 1.5 7.6 3.0 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Kei1 PF08552.11 CDJ52909.1 - 1 9.2 10.9 0.79 9.6 3.2 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 GET2 PF08690.10 CDJ52909.1 - 1.1 8.8 15.0 13 5.4 13.6 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 DUF4568 PF15132.6 CDJ52909.1 - 1.1 8.5 12.2 1.9 7.8 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) DUF648 PF04890.13 CDJ52909.1 - 1.4 8.6 8.9 1.9 8.2 8.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF4050 PF13259.6 CDJ52909.1 - 4 7.7 13.0 0.73 10.1 9.6 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF4050) CCDC53 PF10152.9 CDJ52909.1 - 4.1 7.8 15.1 8.1 6.8 9.2 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex FAM60A PF15396.6 CDJ52909.1 - 4.6 7.2 6.1 7.1 6.6 6.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF2347 PF09804.9 CDJ52909.1 - 5.1 6.6 7.5 10 5.6 6.8 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DUF2052 PF09747.9 CDJ52910.1 - 0.0082 16.3 12.1 0.0082 16.3 12.1 5.4 4 1 1 5 5 5 1 Coiled-coil domain containing protein (DUF2052) p25-alpha PF05517.12 CDJ52911.1 - 1.8e-10 41.2 0.1 2.8e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 p25-alpha SUIM_assoc PF16619.5 CDJ52911.1 - 0.046 13.8 4.0 0.08 13.0 4.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Citrate_synt PF00285.21 CDJ52913.1 - 2.8e-15 56.3 0.2 2.8e-15 56.3 0.2 3.9 3 1 0 3 3 3 1 Citrate synthase, C-terminal domain SR-25 PF10500.9 CDJ52913.1 - 0.015 14.9 2.1 0.022 14.4 2.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4228 PF14009.6 CDJ52913.1 - 7.2 7.0 7.6 17 5.7 5.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CCSAP PF15748.5 CDJ52914.1 - 0.075 13.2 36.7 0.046 13.9 10.6 2.8 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DDHD PF02862.17 CDJ52914.1 - 1.1 9.4 19.7 4.2 7.5 9.2 2.6 2 0 0 2 2 2 0 DDHD domain CPSF100_C PF13299.6 CDJ52914.1 - 1.3 9.2 19.0 0.32 11.2 1.0 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal eIF-3_zeta PF05091.12 CDJ52914.1 - 1.6 7.6 34.8 0.74 8.7 8.7 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.6 CDJ52914.1 - 2.3 8.2 16.8 3.8 7.4 1.1 2.6 2 0 0 2 2 2 0 Protein Family FAM60A SUIM_assoc PF16619.5 CDJ52915.1 - 0.021 14.9 1.6 0.021 14.9 1.6 7.4 6 1 0 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 CemA PF03040.14 CDJ52915.1 - 1.2 9.1 9.8 3.6 7.5 5.0 2.5 2 0 0 2 2 2 0 CemA family CLN3 PF02487.17 CDJ52915.1 - 2.1 7.3 3.2 5.5 5.9 3.2 1.7 1 0 0 1 1 1 0 CLN3 protein RVT_1 PF00078.27 CDJ52917.1 - 6.4e-07 29.1 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RskA PF10099.9 CDJ52919.1 - 1.8e-07 31.6 42.2 0.00081 19.7 10.7 2.1 1 1 1 2 2 2 2 Anti-sigma-K factor rskA DUF2828 PF11443.8 CDJ52919.1 - 0.003 15.7 4.9 0.0038 15.4 4.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF4834 PF16118.5 CDJ52919.1 - 0.013 16.4 11.5 0.57 11.2 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Ndc1_Nup PF09531.10 CDJ52919.1 - 0.031 13.0 8.6 0.036 12.8 8.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RasGEF_N PF00618.20 CDJ52919.1 - 0.14 12.4 0.6 7.3 6.9 0.0 2.1 2 0 0 2 2 2 0 RasGEF N-terminal motif Roughex PF06020.11 CDJ52919.1 - 0.66 9.0 17.2 2.4 7.2 9.3 2.3 2 0 0 2 2 2 0 Drosophila roughex protein DUF3381 PF11861.8 CDJ52919.1 - 0.76 9.6 13.4 0.23 11.3 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) PRC2_HTH_1 PF18118.1 CDJ52919.1 - 1.2 10.0 9.1 0.38 11.6 1.8 2.2 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Hamartin PF04388.12 CDJ52919.1 - 1.2 7.7 12.6 1.4 7.5 12.6 1.0 1 0 0 1 1 1 0 Hamartin protein MLANA PF14991.6 CDJ52919.1 - 1.7 9.0 4.8 6 7.2 0.6 2.3 2 0 0 2 2 2 0 Protein melan-A DUF2722 PF10846.8 CDJ52919.1 - 2.4 7.0 33.3 0.37 9.7 13.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) ATAD4 PF15321.6 CDJ52919.1 - 2.7 9.4 6.0 10 7.6 1.2 2.3 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DivIC PF04977.15 CDJ52919.1 - 3.6 7.4 27.4 3.9 7.3 8.9 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF1387 PF07139.11 CDJ52919.1 - 4.6 6.9 14.7 6.9 6.3 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SRP-alpha_N PF04086.13 CDJ52919.1 - 4.7 7.0 14.7 8.5 6.2 14.7 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Trp_oprn_chp PF09534.10 CDJ52919.1 - 5.2 6.8 36.3 2.3e+02 1.5 38.4 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CNOT1_HEAT PF16418.5 CDJ52919.1 - 5.2 7.1 13.2 5.7 7.0 1.6 2.3 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat TMEM51 PF15345.6 CDJ52919.1 - 6.4 6.5 14.8 0.32 10.8 3.8 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 Pet20 PF08692.10 CDJ52919.1 - 7.5 7.3 6.0 9.3 7.0 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 RuvC_III PF18541.1 CDJ52919.1 - 8 6.4 10.6 2.1 8.2 2.3 2.1 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 CDK2AP PF09806.9 CDJ52920.1 - 7.6 6.5 14.3 11 6.1 14.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2339 PF10101.9 CDJ52921.1 - 7.1 5.1 40.7 11 4.5 40.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF4470 PF14737.6 CDJ52922.1 - 0.011 15.9 0.7 1.9 8.7 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4470) DUF755 PF05501.11 CDJ52922.1 - 0.014 15.7 16.1 0.014 15.7 16.1 9.0 7 3 1 8 8 8 0 Domain of unknown function (DUF755) DUF4471 PF14740.6 CDJ52922.1 - 0.047 12.9 0.2 0.047 12.9 0.2 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4471) DUF572 PF04502.13 CDJ52922.1 - 0.051 13.2 0.1 0.051 13.2 0.1 4.1 3 1 1 4 4 4 0 Family of unknown function (DUF572) AAA_23 PF13476.6 CDJ52922.1 - 1.1 9.7 27.5 72 3.8 0.0 3.9 3 1 0 3 3 3 0 AAA domain WBP-1 PF11669.8 CDJ52925.1 - 0.0061 17.2 1.6 0.0061 17.2 1.6 4.4 4 0 0 4 4 4 1 WW domain-binding protein 1 TB2_DP1_HVA22 PF03134.19 CDJ52925.1 - 0.027 14.4 2.8 0.98 9.4 0.7 2.9 2 0 0 2 2 2 0 TB2/DP1, HVA22 family RskA PF10099.9 CDJ52925.1 - 0.13 12.5 0.0 0.13 12.5 0.0 6.2 2 1 3 5 5 5 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ52925.1 - 0.14 11.8 48.3 0.83 9.2 10.2 4.1 4 0 0 4 4 4 0 Spt20 family Secretin_N_2 PF07655.13 CDJ52925.1 - 2.1 8.9 19.1 1.3 9.6 0.4 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain DUF3774 PF12609.8 CDJ52925.1 - 9.3 7.3 0.0 9.3 7.3 0.0 5.1 5 1 0 5 5 5 0 Wound-induced protein AAA_12 PF13087.6 CDJ52926.1 - 5.3e-47 160.0 0.0 5.3e-47 160.0 0.0 4.8 5 0 0 5 5 5 1 AAA domain AAA_11 PF13086.6 CDJ52926.1 - 1.1e-38 133.6 19.5 8.1e-25 88.1 15.1 14.3 10 4 2 13 13 13 2 AAA domain Sin_N PF04801.13 CDJ52926.1 - 1e-06 28.3 3.6 1e-06 28.3 3.6 11.1 9 4 1 11 11 11 2 Sin-like protein conserved region AAA_19 PF13245.6 CDJ52926.1 - 2.7e-06 27.8 9.4 0.00027 21.3 0.2 5.7 5 1 0 5 5 5 1 AAA domain AAA_23 PF13476.6 CDJ52926.1 - 1.3 9.5 0.0 1.3 9.5 0.0 13.2 12 2 0 12 12 12 0 AAA domain AAA PF00004.29 CDJ52926.1 - 5.6 7.4 14.1 7.3 7.0 5.7 5.4 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Macoilin PF09726.9 CDJ52927.1 - 3.9 5.9 8.8 1.2 7.6 4.1 2.4 2 0 0 2 2 2 0 Macoilin family NESP55 PF06390.12 CDJ52928.1 - 0.00068 19.3 26.0 0.00068 19.3 26.0 2.4 1 1 1 2 2 2 1 Neuroendocrine-specific golgi protein P55 (NESP55) DUF4179 PF13786.6 CDJ52928.1 - 0.67 10.5 0.0 0.67 10.5 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4179) Pneumo_att_G PF05539.11 CDJ52928.1 - 1.8 8.1 13.0 2.3 7.8 13.0 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Hamartin PF04388.12 CDJ52928.1 - 5.2 5.6 11.5 6 5.4 11.5 1.1 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.13 CDJ52928.1 - 6.1 6.5 19.4 9.6 5.8 19.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Autophagy_N PF03986.13 CDJ52929.1 - 6.1e-27 94.2 0.0 8.8e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CDJ52929.1 - 1.1e-21 77.1 0.2 1.9e-21 76.4 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CDJ52929.1 - 8.6e-13 47.6 2.4 1.4e-12 46.8 2.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal SR-25 PF10500.9 CDJ52931.1 - 1.7e-05 24.5 9.9 1.7e-05 24.5 9.9 11.7 8 3 3 11 11 11 5 Nuclear RNA-splicing-associated protein JAB PF01398.21 CDJ52933.1 - 1.2e-26 93.0 0.5 4.5e-26 91.1 0.5 1.9 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CDJ52933.1 - 6.5e-06 25.9 0.1 1.8e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CDJ52933.1 - 0.0075 16.3 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) Ribosomal_S26e PF01283.19 CDJ52934.1 - 1.1e-48 164.2 6.5 1.2e-48 164.0 6.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 CDJ52934.1 - 0.014 16.0 1.1 0.032 14.8 1.1 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain PK PF00224.21 CDJ52935.1 - 2.1e-146 487.3 0.7 2.8e-146 486.9 0.7 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CDJ52935.1 - 1.1e-30 106.3 1.2 2.1e-30 105.3 0.4 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CDJ52935.1 - 0.0038 16.4 1.1 0.011 14.8 0.1 2.2 2 2 1 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family Vps8 PF12816.7 CDJ52935.1 - 0.061 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 Dor1 PF04124.12 CDJ52936.1 - 8.6e-13 47.7 2.4 9.2e-06 24.6 0.0 3.6 2 2 1 3 3 3 2 Dor1-like family Vps51 PF08700.11 CDJ52936.1 - 0.041 14.0 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Vps51/Vps67 Exo84_C PF16528.5 CDJ52936.1 - 0.085 12.7 0.0 0.46 10.3 0.0 2.3 1 1 0 1 1 1 0 Exocyst component 84 C-terminal Sec1 PF00995.23 CDJ52937.1 - 1.6e-67 229.1 0.1 6.4e-50 171.0 0.0 2.0 1 1 1 2 2 2 2 Sec1 family ARHGEF5_35 PF15441.6 CDJ52937.1 - 0.0088 15.1 0.1 0.016 14.2 0.1 1.3 1 0 0 1 1 1 1 Rho guanine nucleotide exchange factor 5/35 DUF1573 PF07610.11 CDJ52938.1 - 7.9e-06 25.8 0.1 1.9e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1573) ASH PF15780.5 CDJ52938.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DSPc PF00782.20 CDJ52939.1 - 3.4e-25 88.4 0.0 5e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ52939.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDJ52939.1 - 0.0029 17.7 0.0 0.0057 16.8 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Proteasome PF00227.26 CDJ52940.1 - 1.4e-59 200.8 0.0 1.7e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ52940.1 - 2.2e-13 49.6 0.2 3.7e-13 48.9 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GM_CSF PF01109.17 CDJ52940.1 - 0.04 14.1 0.1 0.094 12.9 0.1 1.6 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor HEAT PF02985.22 CDJ52941.1 - 3e-09 36.3 24.2 0.031 14.5 0.1 9.2 9 1 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.6 CDJ52941.1 - 5.3e-06 26.8 0.8 5.3e-06 26.8 0.8 8.5 8 0 0 8 8 8 1 HEAT-like repeat IBN_N PF03810.19 CDJ52941.1 - 0.0001 22.2 0.6 0.00067 19.5 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain MMS19_C PF12460.8 CDJ52941.1 - 0.00086 18.5 1.1 7 5.6 0.0 5.0 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 CDJ52941.1 - 0.002 18.5 24.1 0.53 10.7 0.6 8.0 7 5 1 8 8 8 3 HEAT repeats PMEI PF04043.15 CDJ52941.1 - 0.5 10.7 5.3 5.4 7.3 0.2 3.8 3 1 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor OMPdecase PF00215.24 CDJ52942.1 - 5.8e-14 52.2 0.0 9.6e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ribosomal_L35Ae PF01247.18 CDJ52943.1 - 4.2e-41 139.0 1.8 7.3e-41 138.3 1.8 1.4 1 1 0 1 1 1 1 Ribosomal protein L35Ae Ribosomal_S10 PF00338.22 CDJ52944.1 - 5.4e-25 87.5 0.0 6.3e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1922 PF09082.10 CDJ52944.1 - 0.019 15.3 0.1 0.048 14.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1922) EF-hand_1 PF00036.32 CDJ52945.1 - 9.9e-41 134.3 9.3 1.2e-09 37.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ52945.1 - 8.8e-35 119.0 1.8 3.3e-17 62.7 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ52945.1 - 1e-32 111.7 10.4 7.2e-16 57.8 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDJ52945.1 - 2.5e-29 98.7 5.5 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ52945.1 - 3.1e-27 92.8 7.9 2.3e-06 26.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CDJ52945.1 - 5.5e-15 55.5 0.1 4.2e-09 36.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDJ52945.1 - 1.5e-08 34.5 0.3 0.0015 18.5 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ52945.1 - 3.1e-07 30.7 0.1 0.013 15.8 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CDJ52945.1 - 8.9e-06 26.5 0.0 0.0018 19.1 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CDJ52945.1 - 2.8e-05 24.0 0.0 0.042 13.9 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) TerB PF05099.13 CDJ52945.1 - 0.00041 20.3 0.2 0.25 11.3 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 CDJ52945.1 - 0.0016 19.2 0.5 1.2 10.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CDJ52945.1 - 0.0019 18.2 0.1 0.46 10.4 0.0 3.0 1 1 2 3 3 3 1 Caleosin related protein Dockerin_1 PF00404.18 CDJ52945.1 - 0.0023 18.1 3.3 0.24 11.6 0.4 2.8 1 1 1 2 2 2 1 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 CDJ52945.1 - 0.0033 17.7 0.4 1.8 8.9 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 EFhand_Ca_insen PF08726.10 CDJ52945.1 - 0.009 16.1 0.5 0.045 13.9 0.0 2.2 2 2 0 2 2 2 1 Ca2+ insensitive EF hand YqeY PF09424.10 CDJ52945.1 - 0.016 15.3 0.2 0.23 11.5 0.1 2.0 1 1 1 2 2 2 0 Yqey-like protein SurA_N_2 PF13623.6 CDJ52945.1 - 0.02 14.8 0.4 1.1 9.1 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF853 PF05872.12 CDJ52945.1 - 0.025 13.2 0.1 0.71 8.4 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF5580 PF17743.1 CDJ52945.1 - 0.027 13.1 0.0 0.027 13.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 CDJ52945.1 - 0.036 14.4 0.1 10 6.6 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain DUF4497 PF14924.6 CDJ52945.1 - 0.046 14.2 0.0 6.9 7.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) SurA_N_3 PF13624.6 CDJ52945.1 - 0.06 13.1 0.2 0.22 11.3 0.1 1.8 1 1 1 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 CDJ52945.1 - 0.1 12.2 0.3 0.25 10.9 0.3 1.6 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain TetR_C_7 PF14246.6 CDJ52945.1 - 0.11 12.6 0.0 7.6 6.6 0.0 2.3 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain MotA_activ PF09114.10 CDJ52945.1 - 0.14 12.3 0.2 2.8 8.1 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain CwfJ_C_1 PF04677.15 CDJ52947.1 - 4.9e-27 94.2 0.1 8.7e-27 93.4 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CDJ52947.1 - 2.8e-06 28.1 0.0 2.8e-06 28.1 0.0 2.1 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 TFIIA PF03153.13 CDJ52947.1 - 0.1 12.6 24.9 0.19 11.7 24.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PP2C PF00481.21 CDJ52949.1 - 2e-14 53.9 7.2 6.3e-08 32.6 0.0 4.2 4 0 0 4 4 4 3 Protein phosphatase 2C RskA PF10099.9 CDJ52950.1 - 0.00031 21.1 17.8 0.00041 20.7 17.8 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ52950.1 - 0.0055 16.4 23.0 0.0061 16.2 23.0 1.2 1 0 0 1 1 1 1 Spt20 family DUF719 PF05334.13 CDJ52950.1 - 0.013 15.7 7.2 0.018 15.3 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) TFIIA PF03153.13 CDJ52950.1 - 0.016 15.2 26.9 0.017 15.2 26.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ52950.1 - 0.023 13.7 11.6 0.026 13.6 11.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FHIPEP PF00771.20 CDJ52950.1 - 0.024 13.1 4.7 0.026 13.0 4.7 1.0 1 0 0 1 1 1 0 FHIPEP family Peptidase_S49_N PF08496.10 CDJ52950.1 - 0.033 14.3 8.5 0.038 14.1 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.12 CDJ52950.1 - 0.043 12.8 11.7 0.04 12.9 11.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1980 PF09323.10 CDJ52950.1 - 0.045 13.7 2.1 0.047 13.6 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SprA-related PF12118.8 CDJ52950.1 - 0.061 12.4 22.3 0.077 12.1 22.3 1.2 1 0 0 1 1 1 0 SprA-related family Suf PF05843.14 CDJ52950.1 - 0.063 13.3 10.4 0.067 13.2 10.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Connexin PF00029.19 CDJ52950.1 - 0.078 12.7 2.7 0.087 12.6 2.7 1.1 1 0 0 1 1 1 0 Connexin JUPITER PF17054.5 CDJ52950.1 - 0.082 12.4 4.0 0.09 12.2 4.0 1.0 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter SID-1_RNA_chan PF13965.6 CDJ52950.1 - 0.1 11.0 1.3 0.11 10.9 1.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Dala_Dala_lig_N PF01820.21 CDJ52950.1 - 0.15 12.5 1.1 0.23 12.0 1.1 1.3 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus SpoIIP PF07454.11 CDJ52950.1 - 0.16 11.4 6.8 0.18 11.2 6.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) R_equi_Vir PF05526.11 CDJ52950.1 - 0.17 11.7 10.2 0.23 11.3 10.2 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein V_ATPase_I PF01496.19 CDJ52950.1 - 0.19 9.6 6.6 0.17 9.7 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family THOC2_N PF16134.5 CDJ52950.1 - 0.2 10.2 7.7 0.23 10.1 7.7 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DDHD PF02862.17 CDJ52950.1 - 0.24 11.5 8.8 0.27 11.4 8.8 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 CDJ52950.1 - 0.24 11.2 8.5 0.25 11.1 8.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5327 PF17261.2 CDJ52950.1 - 0.26 12.1 14.5 0.36 11.6 14.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5327) EOS1 PF12326.8 CDJ52950.1 - 0.28 11.1 3.0 0.3 11.0 3.0 1.2 1 0 0 1 1 1 0 N-glycosylation protein Presenilin PF01080.17 CDJ52950.1 - 0.35 9.6 10.6 0.38 9.5 10.6 1.1 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 CDJ52950.1 - 0.36 9.7 8.6 0.43 9.5 8.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ureide_permease PF07168.11 CDJ52950.1 - 0.47 9.2 6.3 0.56 8.9 6.3 1.1 1 0 0 1 1 1 0 Ureide permease PAT1 PF09770.9 CDJ52950.1 - 0.47 8.7 16.9 0.5 8.6 16.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2232 PF09991.9 CDJ52950.1 - 0.48 9.6 4.7 0.62 9.2 4.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) CSG2 PF16965.5 CDJ52950.1 - 0.62 9.0 2.3 0.6 9.0 2.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator CLN3 PF02487.17 CDJ52950.1 - 0.67 8.9 3.8 0.72 8.8 3.8 1.2 1 0 0 1 1 1 0 CLN3 protein Sec62 PF03839.16 CDJ52950.1 - 0.7 9.4 5.2 0.69 9.4 5.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S15 PF02129.18 CDJ52950.1 - 0.98 9.0 8.3 1.1 8.7 8.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ctr PF04145.15 CDJ52950.1 - 1.2 9.8 4.1 1.5 9.4 4.1 1.3 1 0 0 1 1 1 0 Ctr copper transporter family ALMT PF11744.8 CDJ52950.1 - 1.5 7.6 8.8 1.6 7.4 8.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Peroxin-13_N PF04088.13 CDJ52950.1 - 1.8 8.8 7.4 2.6 8.3 7.4 1.4 1 1 0 1 1 1 0 Peroxin 13, N-terminal region TMEM174 PF15029.6 CDJ52950.1 - 2.2 8.0 6.7 2.9 7.6 6.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 174 FAM199X PF15814.5 CDJ52950.1 - 2.3 7.2 16.0 2.6 7.0 16.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X Ndc1_Nup PF09531.10 CDJ52950.1 - 2.6 6.6 9.5 2.7 6.6 9.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPP_enzyme_N PF02776.18 CDJ52950.1 - 2.7 7.6 15.4 4.3 6.9 15.4 1.4 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain G0-G1_switch_2 PF15103.6 CDJ52950.1 - 3.7 8.0 13.7 6.3 7.3 13.7 1.6 1 1 0 1 1 1 0 G0/G1 switch protein 2 DUF2722 PF10846.8 CDJ52950.1 - 3.7 6.4 26.1 5.4 5.8 26.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) HemX PF04375.14 CDJ52950.1 - 8.5 5.6 26.8 10 5.3 26.8 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase RskA PF10099.9 CDJ52951.1 - 5.6e-05 23.5 13.2 5.6e-05 23.5 13.2 4.7 3 1 0 4 4 4 2 Anti-sigma-K factor rskA WD40 PF00400.32 CDJ52951.1 - 0.0056 17.5 10.3 0.71 10.9 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Hirudin PF00713.17 CDJ52951.1 - 0.0073 16.6 1.0 0.0073 16.6 1.0 2.8 3 0 0 3 3 3 1 Hirudin PIG-U PF06728.13 CDJ52951.1 - 0.01 14.9 0.1 0.018 14.1 0.1 1.4 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U Pex14_N PF04695.13 CDJ52952.1 - 0.0044 17.7 8.3 0.0044 17.7 8.3 5.2 4 1 1 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 CDJ52952.1 - 0.0062 15.5 19.6 0.066 12.1 12.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52952.1 - 0.0071 16.0 29.1 0.085 12.5 15.7 2.3 2 0 0 2 2 2 2 Spt20 family CDK2AP PF09806.9 CDJ52953.1 - 0.056 13.5 17.9 0.03 14.4 7.1 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF3995 PF13160.6 CDJ52953.1 - 0.29 11.5 10.6 2 8.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Ribosomal_60s PF00428.19 CDJ52953.1 - 0.45 11.1 25.9 0.23 12.1 6.8 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein EF-hand_7 PF13499.6 CDJ52954.1 - 8e-07 29.4 0.6 0.00016 22.1 0.0 2.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CDJ52954.1 - 2.4e-06 26.7 0.1 0.00082 18.8 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ52954.1 - 4.6e-06 26.4 0.1 0.00063 19.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ52954.1 - 4.9e-05 22.9 0.3 0.031 14.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain RskA PF10099.9 CDJ52954.1 - 0.00016 22.0 63.0 0.00052 20.4 8.7 4.9 3 1 1 4 4 4 3 Anti-sigma-K factor rskA GETHR PF05671.11 CDJ52954.1 - 0.00059 19.1 7.5 0.0042 16.4 0.0 4.4 4 1 0 4 4 4 1 GETHR pentapeptide repeat (5 copies) EF-hand_5 PF13202.6 CDJ52954.1 - 0.024 14.1 0.1 0.067 12.7 0.1 1.7 1 0 0 1 1 1 0 EF hand Ribosomal_60s PF00428.19 CDJ52954.1 - 5 7.8 47.6 2.1 9.0 14.4 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein 30K_MP_C_Ter PF11330.8 CDJ52955.1 - 1.2 8.5 2.6 2.2 7.5 2.6 1.4 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins Velvet PF11754.8 CDJ52956.1 - 0.017 15.1 32.0 0.17 11.8 5.7 3.7 3 0 0 3 3 3 0 Velvet factor SARAF PF06682.12 CDJ52957.1 - 3.7e-06 26.8 1.2 4.3e-06 26.6 1.2 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis V_ATPase_I PF01496.19 CDJ52957.1 - 2e-05 22.8 11.2 2.3e-05 22.5 11.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Pex14_N PF04695.13 CDJ52957.1 - 0.00015 22.5 19.6 0.0002 22.1 19.6 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ52957.1 - 0.00045 20.1 2.3 0.00053 19.8 2.3 1.1 1 0 0 1 1 1 1 Connexin Sin_N PF04801.13 CDJ52957.1 - 0.0008 18.7 17.3 0.00093 18.5 17.3 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region CSG2 PF16965.5 CDJ52957.1 - 0.0012 17.9 0.8 0.0013 17.8 0.8 1.0 1 0 0 1 1 1 1 Ceramide synthase regulator EOS1 PF12326.8 CDJ52957.1 - 0.0012 18.8 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 N-glycosylation protein DUF4199 PF13858.6 CDJ52957.1 - 0.0019 18.6 0.0 0.0048 17.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) CLN3 PF02487.17 CDJ52957.1 - 0.002 17.3 4.6 0.0023 17.0 4.6 1.1 1 0 0 1 1 1 1 CLN3 protein PIP5K PF01504.18 CDJ52957.1 - 0.0022 17.2 3.5 0.0025 17.1 3.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SID-1_RNA_chan PF13965.6 CDJ52957.1 - 0.0034 15.9 0.1 0.0038 15.7 0.1 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 TRAP_alpha PF03896.16 CDJ52957.1 - 0.0068 15.7 0.2 0.0082 15.4 0.2 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Serinc PF03348.15 CDJ52957.1 - 0.013 14.5 0.4 0.013 14.4 0.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2370 PF10176.9 CDJ52957.1 - 0.015 14.9 4.3 0.02 14.6 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Neur_chan_memb PF02932.16 CDJ52957.1 - 0.015 15.3 5.4 0.017 15.2 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Velvet PF11754.8 CDJ52957.1 - 0.018 15.0 9.1 0.019 14.9 9.1 1.1 1 0 0 1 1 1 0 Velvet factor Trp_oprn_chp PF09534.10 CDJ52957.1 - 0.019 14.8 0.3 0.032 14.0 0.4 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Endostatin PF06482.11 CDJ52957.1 - 0.027 13.9 8.6 0.029 13.8 8.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4366 PF14283.6 CDJ52957.1 - 0.03 14.4 0.2 0.052 13.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3295 PF11702.8 CDJ52957.1 - 0.033 13.5 10.0 0.04 13.3 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) RIC3 PF15361.6 CDJ52957.1 - 0.034 14.5 6.3 0.047 14.1 6.3 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 BORG_CEP PF14957.6 CDJ52957.1 - 0.036 15.2 3.3 0.042 15.0 3.3 1.2 1 0 0 1 1 1 0 Cdc42 effector Presenilin PF01080.17 CDJ52957.1 - 0.056 12.2 12.6 0.07 11.9 12.6 1.1 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 CDJ52957.1 - 0.087 10.9 7.4 0.1 10.7 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) O-antigen_lig PF13425.6 CDJ52957.1 - 0.088 11.6 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein HemX PF04375.14 CDJ52957.1 - 0.096 11.9 19.0 0.1 11.9 19.0 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2207 PF09972.9 CDJ52957.1 - 0.15 10.8 0.3 0.29 9.9 0.1 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) RR_TM4-6 PF06459.12 CDJ52957.1 - 0.15 11.8 12.9 0.2 11.5 12.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 CDJ52957.1 - 0.18 11.2 19.1 0.23 10.8 19.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HCO3_cotransp PF00955.21 CDJ52957.1 - 0.21 10.4 0.3 0.24 10.2 0.3 1.1 1 0 0 1 1 1 0 HCO3- transporter family CCDC53 PF10152.9 CDJ52957.1 - 0.23 11.9 12.8 0.31 11.5 12.8 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF5427 PF10310.9 CDJ52957.1 - 0.27 10.2 14.8 0.34 9.8 14.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) TYW3 PF02676.14 CDJ52957.1 - 0.27 10.5 4.0 0.28 10.5 4.0 1.1 1 0 0 1 1 1 0 Methyltransferase TYW3 RAMP4 PF06624.12 CDJ52957.1 - 0.28 11.3 0.0 0.28 11.3 0.0 2.1 3 0 0 3 3 2 0 Ribosome associated membrane protein RAMP4 Membralin PF09746.9 CDJ52957.1 - 0.31 10.0 2.6 0.35 9.9 2.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein PBP1_TM PF14812.6 CDJ52957.1 - 0.4 11.1 6.2 0.16 12.3 1.7 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EIIBC-GUT_N PF03612.14 CDJ52957.1 - 0.56 9.9 14.7 4.3 7.0 14.7 1.9 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FUN14 PF04930.15 CDJ52957.1 - 0.58 10.6 1.9 1 9.8 1.9 1.5 1 1 0 1 1 1 0 FUN14 family DUF2126 PF09899.9 CDJ52957.1 - 0.62 8.1 11.6 0.76 7.8 11.6 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DcuA_DcuB PF03605.14 CDJ52957.1 - 0.73 8.7 2.2 0.6 8.9 1.2 1.3 1 1 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter ALMT PF11744.8 CDJ52957.1 - 0.81 8.4 7.6 0.95 8.2 7.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Kei1 PF08552.11 CDJ52957.1 - 1.1 9.1 6.0 1.6 8.6 6.0 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Gti1_Pac2 PF09729.9 CDJ52957.1 - 1.2 9.2 11.7 1.6 8.8 11.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family INSIG PF07281.12 CDJ52957.1 - 1.4 8.5 6.3 11 5.6 6.7 1.9 1 1 0 1 1 1 0 Insulin-induced protein (INSIG) DUF4746 PF15928.5 CDJ52957.1 - 1.5 8.1 10.2 2 7.8 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Tmemb_9 PF05434.11 CDJ52957.1 - 1.9 8.4 13.3 3.2 7.6 13.4 1.3 1 1 0 1 1 1 0 TMEM9 CrgA PF06781.12 CDJ52957.1 - 1.9 8.6 7.8 14 5.8 7.8 2.2 1 1 0 1 1 1 0 Cell division protein CrgA Tim54 PF11711.8 CDJ52957.1 - 2.1 7.1 13.1 2.6 6.7 13.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3292 PF11696.8 CDJ52957.1 - 2.6 6.3 9.1 3.3 6.0 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) SLC12 PF03522.15 CDJ52957.1 - 2.9 6.8 13.2 3.7 6.5 13.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SKA1 PF07160.12 CDJ52957.1 - 3.1 7.6 15.6 4 7.2 15.6 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DDRGK PF09756.9 CDJ52957.1 - 3.1 7.4 19.0 3.8 7.1 19.0 1.1 1 0 0 1 1 1 0 DDRGK domain FAM60A PF15396.6 CDJ52957.1 - 3.2 7.7 12.1 4.2 7.3 12.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A ArsP_2 PF11449.8 CDJ52957.1 - 3.2 6.9 5.3 4.7 6.3 5.3 1.3 1 1 0 1 1 1 0 Putative, 10TM heavy-metal exporter TMEM65 PF10507.9 CDJ52957.1 - 3.9 7.5 4.4 0.54 10.2 0.4 1.7 2 0 0 2 2 1 0 Transmembrane protein 65 Orf78 PF06024.12 CDJ52957.1 - 4.6 7.6 10.9 16 5.9 8.5 2.4 1 1 1 2 2 2 0 Orf78 (ac78) GET2 PF08690.10 CDJ52957.1 - 5.3 6.6 14.3 6.9 6.2 14.3 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Peptidase_S64 PF08192.11 CDJ52957.1 - 7.5 4.9 11.9 9.1 4.6 11.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 PIG-U PF06728.13 CDJ52957.1 - 10 5.1 8.3 24 3.8 8.3 1.6 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U AF-4 PF05110.13 CDJ52958.1 - 4.6 5.2 35.6 7 4.6 35.6 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MAP65_ASE1 PF03999.12 CDJ52958.1 - 9.3 4.8 15.0 15 4.1 15.0 1.5 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Sporozoite_P67 PF05642.11 CDJ52959.1 - 0.52 8.3 2.9 0.66 8.0 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.8 CDJ52959.1 - 1.4 8.0 14.1 2.1 7.5 14.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TSC22 PF01166.18 CDJ52960.1 - 0.012 15.9 2.4 0.012 15.9 2.4 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family MIP-T3_C PF17749.1 CDJ52960.1 - 0.19 11.7 13.9 0.049 13.6 6.2 2.9 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Spc7 PF08317.11 CDJ52960.1 - 0.21 10.4 29.3 0.4 9.5 18.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein zf-C4H2 PF10146.9 CDJ52960.1 - 0.31 11.3 13.1 0.077 13.3 7.5 2.7 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4618 PF15397.6 CDJ52960.1 - 0.45 9.9 18.0 0.044 13.2 11.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) HALZ PF02183.18 CDJ52960.1 - 0.54 10.5 6.9 0.071 13.4 2.1 2.0 2 0 0 2 2 1 0 Homeobox associated leucine zipper CREPT PF16566.5 CDJ52960.1 - 0.79 9.9 14.7 0.64 10.2 9.4 2.5 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Fungal_TACC PF12709.7 CDJ52960.1 - 1 9.8 6.5 24 5.5 0.1 2.7 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Fez1 PF06818.15 CDJ52960.1 - 1.3 9.4 24.6 0.27 11.6 20.0 2.1 1 1 1 2 2 2 0 Fez1 Golgin_A5 PF09787.9 CDJ52960.1 - 2 7.8 29.6 0.46 9.9 19.2 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 FliJ PF02050.16 CDJ52960.1 - 3.1 8.1 30.5 8.6 6.6 12.6 2.8 1 1 1 2 2 2 0 Flagellar FliJ protein DUF641 PF04859.12 CDJ52960.1 - 4.1 7.8 18.0 0.42 10.9 8.1 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.9 CDJ52960.1 - 5.2 7.1 35.3 0.3 11.1 4.3 3.4 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 CDJ52960.1 - 5.2 7.1 11.3 19 5.3 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 CDJ52960.1 - 5.6 7.2 23.7 5.7 7.2 12.3 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ccdc124 PF06244.12 CDJ52961.1 - 7.9e-33 113.8 23.5 3.2e-30 105.3 23.5 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 CDJ52961.1 - 7.6e-05 23.1 0.4 7.6e-05 23.1 0.4 2.5 2 1 0 2 2 2 1 HMG (high mobility group) box CHDNT PF08073.12 CDJ52961.1 - 0.014 15.3 0.3 0.023 14.6 0.3 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain Mem_trans PF03547.18 CDJ52961.1 - 0.13 10.6 1.4 0.15 10.4 1.4 1.0 1 0 0 1 1 1 0 Membrane transport protein YABBY PF04690.13 CDJ52961.1 - 1.3 9.5 9.9 24 5.4 9.9 2.2 1 1 0 1 1 1 0 YABBY protein VSG_B PF13206.6 CDJ52961.1 - 1.4 8.1 13.2 1.7 7.8 13.2 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain FliG_C PF01706.16 CDJ52962.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 FliG C-terminal domain PAM2 PF07145.15 CDJ52963.1 - 0.0072 15.9 0.5 0.015 14.9 0.5 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region fn2 PF00040.19 CDJ52964.1 - 1.1 9.6 6.0 1.8 8.9 1.4 2.2 2 0 0 2 2 2 0 Fibronectin type II domain eRF1_1 PF03463.15 CDJ52965.1 - 2.9e-28 98.5 0.3 5.4e-28 97.6 0.0 1.7 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.15 CDJ52965.1 - 8.6e-16 58.4 0.0 3e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 CDJ52965.1 - 1.3e-14 54.6 0.0 2.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 MMACHC PF16690.5 CDJ52965.1 - 0.007 16.0 0.3 0.012 15.2 0.3 1.4 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family SR-25 PF10500.9 CDJ52965.1 - 0.92 9.1 11.3 0.029 14.0 3.6 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Paf1 PF03985.13 CDJ52965.1 - 1.3 7.9 8.5 2.2 7.2 8.5 1.4 1 0 0 1 1 1 0 Paf1 baeRF_family12 PF18856.1 CDJ52965.1 - 1.5 9.4 7.5 10 6.7 0.1 2.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 DUF4698 PF15769.5 CDJ52965.1 - 3.7 6.5 11.9 2.8 6.9 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) DUF4366 PF14283.6 CDJ52966.1 - 0.011 15.8 5.5 0.011 15.8 5.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) CDC45 PF02724.14 CDJ52966.1 - 0.039 12.3 11.6 0.053 11.8 11.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4471 PF14740.6 CDJ52966.1 - 0.17 11.1 12.5 0.25 10.6 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Tox-WTIP PF15654.6 CDJ52966.1 - 0.23 11.9 0.1 0.23 11.9 0.1 4.5 4 1 0 4 4 4 0 Toxin with a conserved tryptophan and TIP tripeptide motif GPCR_chapero_1 PF11904.8 CDJ52966.1 - 0.51 9.7 11.1 0.86 9.0 11.1 1.4 1 0 0 1 1 1 0 GPCR-chaperone XRN_M PF17846.1 CDJ52966.1 - 0.77 8.6 11.6 1.3 7.9 11.6 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Zip PF02535.22 CDJ52966.1 - 1.4 8.1 10.0 0.066 12.4 3.7 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter SLC12 PF03522.15 CDJ52966.1 - 1.4 7.9 26.3 0.84 8.6 24.7 1.4 2 0 0 2 2 2 0 Solute carrier family 12 CSG2 PF16965.5 CDJ52966.1 - 1.8 7.4 12.8 3 6.7 12.8 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Otopetrin PF03189.13 CDJ52966.1 - 2.2 7.0 7.8 3.5 6.3 7.8 1.5 1 0 0 1 1 1 0 Otopetrin N6_N4_Mtase PF01555.18 CDJ52966.1 - 2.7 7.6 6.9 4.1 7.0 6.9 1.2 1 0 0 1 1 1 0 DNA methylase Ureide_permease PF07168.11 CDJ52966.1 - 2.9 6.6 8.9 5.2 5.7 8.9 1.5 1 0 0 1 1 1 0 Ureide permease Nha1_C PF08619.10 CDJ52966.1 - 4.2 6.5 25.2 0.86 8.7 19.8 2.0 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF2126 PF09899.9 CDJ52966.1 - 4.7 5.1 12.3 6.8 4.6 12.3 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF3464 PF11947.8 CDJ52966.1 - 5 6.9 17.8 0.25 11.1 10.8 2.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 PBP1_TM PF14812.6 CDJ52966.1 - 5.3 7.5 9.4 9.2 6.7 9.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cellulose_synt PF03552.14 CDJ52966.1 - 5.4 5.4 6.1 6.9 5.0 6.1 1.1 1 0 0 1 1 1 0 Cellulose synthase VIR_N PF15912.5 CDJ52966.1 - 7.5 6.1 15.9 14 5.1 15.9 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal SID-1_RNA_chan PF13965.6 CDJ52966.1 - 7.9 4.8 12.0 12 4.1 12.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 CDJ52966.1 - 8.5 6.1 23.4 20 4.9 23.4 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TCP PF03634.13 CDJ52967.1 - 0.81 10.2 22.3 2.8 8.5 4.0 2.3 2 0 0 2 2 2 0 TCP family transcription factor Apt1 PF10351.9 CDJ52967.1 - 1.9 7.2 38.6 1.1 8.1 19.3 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain SAPS PF04499.15 CDJ52967.1 - 2.7 6.7 8.1 0.17 10.6 1.9 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 CDJ52967.1 - 3.8 6.2 14.9 0.5 9.1 5.7 2.1 2 0 0 2 2 2 0 Presenilin Sin_N PF04801.13 CDJ52968.1 - 0.034 13.4 0.0 0.034 13.4 0.0 8.0 5 3 2 8 8 8 0 Sin-like protein conserved region RRM_1 PF00076.22 CDJ52969.1 - 1.7e-08 34.1 0.2 2.7e-07 30.3 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RskA PF10099.9 CDJ52969.1 - 0.79 10.0 0.0 0.22 11.8 15.5 11.8 1 1 7 8 8 8 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ52970.1 - 0.039 14.3 11.2 0.054 13.8 11.2 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ52970.1 - 0.12 12.3 27.8 0.14 12.2 27.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ANAPC1 PF12859.7 CDJ52970.1 - 8.1 7.0 19.0 3e+02 1.9 19.0 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 SID-1_RNA_chan PF13965.6 CDJ52971.1 - 0.42 9.0 9.3 0.52 8.7 9.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 O-antigen_lig PF13425.6 CDJ52971.1 - 5.6 5.6 8.7 6 5.5 8.7 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SprA-related PF12118.8 CDJ52971.1 - 7.8 5.5 58.3 12 4.9 58.3 1.2 1 0 0 1 1 1 0 SprA-related family SUIM_assoc PF16619.5 CDJ52972.1 - 0.0021 18.1 0.2 0.0021 18.1 0.2 4.1 2 2 1 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 HHH_8 PF14716.6 CDJ52972.1 - 0.0054 17.1 0.3 0.011 16.1 0.3 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain PUL PF08324.11 CDJ52972.1 - 0.0062 15.8 0.3 0.0089 15.3 0.3 1.2 1 0 0 1 1 1 1 PUL domain Sin_N PF04801.13 CDJ52972.1 - 0.27 10.4 18.2 0.46 9.6 18.2 1.4 1 1 0 1 1 1 0 Sin-like protein conserved region Presenilin PF01080.17 CDJ52972.1 - 0.28 9.9 10.2 0.4 9.4 10.2 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S46 PF10459.9 CDJ52972.1 - 1.1 7.8 12.4 1.6 7.3 12.4 1.2 1 0 0 1 1 1 0 Peptidase S46 DivIC PF04977.15 CDJ52972.1 - 6.5 6.6 29.0 0.68 9.7 9.0 2.2 2 0 0 2 2 2 0 Septum formation initiator SR-25 PF10500.9 CDJ52973.1 - 0.00025 20.7 4.7 0.00025 20.7 4.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Spt5_N PF11942.8 CDJ52973.1 - 0.00057 20.8 14.9 0.0012 19.7 4.3 2.1 2 0 0 2 2 2 2 Spt5 transcription elongation factor, acidic N-terminal CCDC106 PF15794.5 CDJ52973.1 - 0.064 13.0 5.7 0.067 12.9 5.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Protamine_P2 PF00841.19 CDJ52973.1 - 0.12 12.9 8.5 0.051 14.1 6.6 1.4 1 1 0 1 1 1 0 Sperm histone P2 TFIIF_alpha PF05793.12 CDJ52973.1 - 0.15 10.6 13.6 0.16 10.6 13.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FXMRP1_C_core PF12235.8 CDJ52973.1 - 1 10.0 12.9 1.9 9.2 12.3 1.6 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal DUF5427 PF10310.9 CDJ52974.1 - 0.1 11.5 28.8 0.11 11.4 28.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SARAF PF06682.12 CDJ52974.1 - 1.7 8.2 28.0 1.8 8.2 28.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF913 PF06025.12 CDJ52974.1 - 2.5 7.0 15.9 3.4 6.5 15.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM76 PF16046.5 CDJ52974.1 - 6.6 6.0 31.3 8.7 5.6 31.3 1.3 1 0 0 1 1 1 0 FAM76 protein SLC12 PF03522.15 CDJ52974.1 - 9.3 5.1 31.5 10 5.0 31.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4667 PF15700.5 CDJ52976.1 - 0.0032 17.6 2.5 0.0032 17.6 2.5 4.5 3 1 1 4 4 4 1 Domain of unknown function (DUF4667) DUF5305 PF17231.2 CDJ52976.1 - 0.02 14.3 7.9 0.4 10.1 2.1 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5305) Peptidase_C48 PF02902.19 CDJ52977.1 - 3.6e-15 56.4 0.0 3.6e-15 56.4 0.0 1.6 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain RskA PF10099.9 CDJ52977.1 - 0.00046 20.5 4.2 0.00046 20.5 4.2 3.1 2 1 0 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ52977.1 - 0.79 9.7 30.9 1.9 8.4 6.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tic110 PF16940.5 CDJ52977.1 - 1.1 7.7 12.5 3.3 6.1 7.9 2.1 2 0 0 2 2 2 0 Chloroplast envelope transporter DUF4834 PF16118.5 CDJ52977.1 - 8.9 7.4 9.5 11 7.0 4.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 CDJ52978.1 - 8.4e-42 143.3 0.0 1.3e-41 142.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ52978.1 - 1.1e-18 67.5 0.0 1.7e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_1N PF02870.15 CDJ52979.1 - 1.9 9.3 4.8 1.5 9.7 1.8 2.4 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Spc7 PF08317.11 CDJ52979.1 - 2.6 6.9 43.9 0.24 10.2 14.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein GAGA_bind PF06217.12 CDJ52979.1 - 8.6 6.6 17.4 12 6.0 17.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family LRR_6 PF13516.6 CDJ52982.1 - 0.014 15.4 0.0 2.8 8.2 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Hydrolase_4 PF12146.8 CDJ52983.1 - 5e-13 48.9 0.0 3e-08 33.2 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ52983.1 - 7.6e-09 35.6 0.0 1.7e-05 24.6 0.0 2.7 1 1 2 3 3 3 2 alpha/beta hydrolase fold AXE1 PF05448.12 CDJ52983.1 - 4.2e-07 28.9 0.1 0.0037 16.0 0.0 3.0 1 1 2 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 CDJ52983.1 - 3.9e-06 26.5 0.0 8.4e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CDJ52983.1 - 8.8e-06 26.5 0.0 2.3e-05 25.1 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CDJ52983.1 - 4.7e-05 23.1 0.0 0.00014 21.5 0.0 1.6 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 CDJ52983.1 - 9.2e-05 22.1 0.0 0.0007 19.2 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 CDJ52983.1 - 0.00023 20.9 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CDJ52983.1 - 0.00047 20.0 0.0 0.0033 17.2 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CDJ52983.1 - 0.00097 19.1 0.0 0.0019 18.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 CDJ52983.1 - 0.014 14.9 0.0 0.39 10.2 0.0 2.3 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase DUF818 PF05677.12 CDJ52983.1 - 0.015 14.2 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.11 CDJ52983.1 - 0.021 14.7 0.0 0.11 12.5 0.0 1.9 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 CDJ52983.1 - 0.18 11.6 0.0 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF1057 PF06342.12 CDJ52983.1 - 0.2 10.6 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 CDJ52985.1 - 4.9e-16 58.7 0.0 1.6e-12 47.2 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ52985.1 - 1.7e-11 44.3 0.3 1.4e-09 38.0 0.2 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ52985.1 - 4.8e-10 40.4 0.2 8.6e-10 39.6 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 CDJ52985.1 - 1.9e-06 26.8 0.0 0.0041 15.8 0.0 2.6 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 CDJ52985.1 - 6.1e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.12 CDJ52985.1 - 0.00024 20.2 0.0 0.00039 19.5 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.13 CDJ52985.1 - 0.0047 16.8 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CDJ52985.1 - 0.025 14.4 0.0 0.2 11.4 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 CDJ52985.1 - 0.032 13.8 0.0 0.15 11.7 0.0 1.8 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 CDJ52985.1 - 0.033 13.8 0.0 0.096 12.2 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.13 CDJ52985.1 - 0.037 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.25 CDJ52985.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 CDJ52985.1 - 0.22 11.3 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family TAFII55_N PF04658.13 CDJ52986.1 - 3.6e-18 65.8 0.7 1.7e-17 63.6 0.0 2.6 2 1 0 2 2 2 1 TAFII55 protein conserved region TFIIA PF03153.13 CDJ52988.1 - 0.00093 19.3 15.4 0.0016 18.5 15.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ52988.1 - 0.051 12.3 0.7 0.08 11.7 0.7 1.2 1 0 0 1 1 1 0 Presenilin RIC3 PF15361.6 CDJ52988.1 - 0.54 10.6 4.5 1.5 9.2 3.9 1.9 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 CCDC53 PF10152.9 CDJ52988.1 - 2 8.9 10.4 0.67 10.4 3.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SspB PF04386.13 CDJ52988.1 - 5.7 6.8 13.6 0.3 11.0 8.1 1.6 2 0 0 2 2 2 0 Stringent starvation protein B ANAPC_CDC26 PF10471.9 CDJ52988.1 - 8.8 7.2 22.6 13 6.7 3.8 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4744 PF15918.5 CDJ52989.1 - 0.21 12.5 0.0 0.29 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Ank_5 PF13857.6 CDJ52992.1 - 3.4e-08 33.6 0.4 6.2e-06 26.4 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ52992.1 - 9e-08 32.6 0.0 1.4e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ52992.1 - 1.1e-06 29.1 0.0 8.8e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ52992.1 - 6.8e-06 26.0 0.1 0.93 10.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CDJ52992.1 - 0.0011 19.3 0.1 1.5 9.4 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat DUF2722 PF10846.8 CDJ52992.1 - 0.0039 16.2 0.2 0.0039 16.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ52992.1 - 0.0039 16.8 3.3 0.0044 16.7 3.3 1.2 1 0 0 1 1 1 1 Spt20 family PDZ_3 PF17815.1 CDJ52992.1 - 0.0091 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 PDZ domain Med3 PF11593.8 CDJ52992.1 - 0.11 11.6 5.1 0.13 11.4 5.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal EF-hand_5 PF13202.6 CDJ52992.1 - 0.2 11.2 0.5 0.89 9.2 0.0 2.0 2 0 0 2 2 2 0 EF hand Androgen_recep PF02166.16 CDJ52992.1 - 2.3 7.0 11.0 2.7 6.7 11.0 1.1 1 0 0 1 1 1 0 Androgen receptor Hen1_Lam_C PF18441.1 CDJ52993.1 - 0.088 12.7 0.2 0.52 10.2 0.2 2.4 1 0 0 1 1 1 0 Hen1 La-motif C-terminal domain AAA_23 PF13476.6 CDJ52995.1 - 0.022 15.3 1.4 0.022 15.3 1.4 3.3 2 1 0 2 2 2 0 AAA domain PAP1 PF08601.10 CDJ52995.1 - 1.9 8.1 51.9 16 5.1 29.6 2.4 1 1 1 2 2 2 0 Transcription factor PAP1 LTV PF04180.14 CDJ52995.1 - 5.1 6.7 37.0 0.14 11.9 10.7 2.6 2 1 0 2 2 2 0 Low temperature viability protein DUF5327 PF17261.2 CDJ52996.1 - 0.24 12.2 16.3 0.26 12.0 16.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5327) DDHD PF02862.17 CDJ52996.1 - 1.9 8.6 10.6 2.1 8.5 10.6 1.0 1 0 0 1 1 1 0 DDHD domain Helicase_C PF00271.31 CDJ52997.1 - 0.0025 18.1 14.7 0.0057 17.0 0.0 5.3 3 1 1 4 4 4 2 Helicase conserved C-terminal domain Apt1 PF10351.9 CDJ52997.1 - 0.023 13.6 0.0 0.023 13.6 0.0 16.2 4 4 3 7 7 7 0 Golgi-body localisation protein domain DUF3169 PF11368.8 CDJ52997.1 - 0.21 11.1 0.3 13 5.2 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) RFXA_RFXANK_bdg PF15289.6 CDJ52998.1 - 0.032 14.5 7.5 0.032 14.5 7.5 3.4 3 0 0 3 3 1 0 Regulatory factor X-associated C-terminal binding domain DUF4418 PF14387.6 CDJ52998.1 - 0.039 14.2 0.1 0.076 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) DUF3824 PF12868.7 CDJ52998.1 - 0.049 14.3 0.6 0.049 14.3 0.6 3.3 2 1 0 2 2 1 0 Domain of unknwon function (DUF3824) Rft-1 PF04506.13 CDJ52998.1 - 0.05 12.4 0.4 0.1 11.3 0.0 1.4 1 1 0 1 1 1 0 Rft protein DUF4834 PF16118.5 CDJ52998.1 - 0.12 13.3 19.7 1.1 10.3 3.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF5327 PF17261.2 CDJ52998.1 - 0.21 12.4 30.6 0.28 11.9 8.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5327) DUF3357 PF11837.8 CDJ52998.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) DUF533 PF04391.12 CDJ52998.1 - 0.29 10.7 37.4 0.14 11.7 17.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF533) Mss4 PF04421.13 CDJ52998.1 - 0.51 10.5 8.1 9.8 6.4 0.6 3.3 3 0 0 3 3 3 0 Mss4 protein UPF0524 PF15823.5 CDJ52998.1 - 2.1 7.7 16.0 0.85 9.0 0.1 3.1 3 0 0 3 3 3 0 UPF0524 of C3orf70 DUF3371 PF11851.8 CDJ52998.1 - 2.2 9.4 30.7 2.2 9.4 3.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3371) TrbI PF03743.14 CDJ52998.1 - 4 7.2 17.5 0.11 12.4 4.2 2.3 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein RED_N PF07808.13 CDJ52998.1 - 4.3 6.8 25.1 0.11 12.1 1.6 3.1 3 0 0 3 3 3 0 RED-like protein N-terminal region GREB1 PF15782.5 CDJ52999.1 - 0.27 8.3 37.9 0.33 8.0 37.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDJ52999.1 - 0.52 8.8 33.2 0.72 8.3 33.2 1.2 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 CDJ52999.1 - 0.85 9.3 24.3 1.2 8.8 24.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 GAGA_bind PF06217.12 CDJ52999.1 - 3.7 7.8 30.4 5.4 7.2 30.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family TMPIT PF07851.13 CDJ53000.1 - 0.011 15.1 3.8 0.013 14.8 3.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 CDJ53000.1 - 0.042 13.4 8.8 0.045 13.3 8.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.13 CDJ53000.1 - 0.058 13.4 27.7 0.065 13.2 27.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MCU PF04678.13 CDJ53000.1 - 0.1 12.7 5.3 0.14 12.3 5.3 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Aminotran_1_2 PF00155.21 CDJ53000.1 - 0.34 10.0 5.2 0.38 9.9 5.2 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II ZYG-11_interact PF05884.12 CDJ53000.1 - 0.34 10.3 5.5 0.37 10.2 5.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF4199 PF13858.6 CDJ53000.1 - 0.39 11.1 3.5 0.58 10.5 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2232 PF09991.9 CDJ53000.1 - 0.43 9.7 2.7 0.47 9.6 2.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Macoilin PF09726.9 CDJ53000.1 - 0.44 9.0 14.1 0.57 8.7 14.1 1.2 1 0 0 1 1 1 0 Macoilin family NYN_YacP PF05991.11 CDJ53000.1 - 0.7 9.8 7.1 0.97 9.3 7.1 1.1 1 0 0 1 1 1 0 YacP-like NYN domain PAT1 PF09770.9 CDJ53000.1 - 0.96 7.6 14.5 0.96 7.6 14.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HemX PF04375.14 CDJ53000.1 - 1.1 8.4 22.2 1.4 8.1 22.2 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase PspB PF06667.12 CDJ53000.1 - 1.6 8.8 5.1 2.4 8.3 5.1 1.2 1 0 0 1 1 1 0 Phage shock protein B DUF4175 PF13779.6 CDJ53000.1 - 1.8 6.4 22.1 2.1 6.1 22.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spt20 PF12090.8 CDJ53000.1 - 2 7.9 21.5 2.9 7.4 21.5 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ53000.1 - 2.9 7.8 10.4 3.6 7.5 10.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SARAF PF06682.12 CDJ53001.1 - 0.0023 17.7 32.5 0.0023 17.7 32.5 8.3 7 1 1 8 8 8 2 SOCE-associated regulatory factor of calcium homoeostasis SR-25 PF10500.9 CDJ53001.1 - 0.0044 16.7 3.4 0.0044 16.7 3.4 12.4 7 2 4 12 12 12 2 Nuclear RNA-splicing-associated protein DUF4179 PF13786.6 CDJ53001.1 - 1.1 9.8 0.0 1.1 9.8 0.0 15.2 12 7 0 12 12 12 0 Domain of unknown function (DUF4179) DUF572 PF04502.13 CDJ53002.1 - 2.1 7.9 17.9 2.3 7.7 17.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Miga PF10265.9 CDJ53002.1 - 2.2 7.2 13.8 2.3 7.1 13.8 1.3 1 0 0 1 1 1 0 Mitoguardin Lin-8 PF03353.15 CDJ53002.1 - 2.5 7.6 10.2 3.7 7.0 10.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Smg8_Smg9 PF10220.9 CDJ53002.1 - 7.1 4.8 12.0 6.9 4.8 12.0 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Pex14_N PF04695.13 CDJ53003.1 - 0.042 14.5 25.9 0.054 14.1 25.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pdase_M17_N2 PF18295.1 CDJ53003.1 - 0.052 13.8 5.8 0.067 13.4 5.8 1.2 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 Zip PF02535.22 CDJ53003.1 - 0.12 11.6 10.2 0.13 11.4 10.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Auxin_canalis PF05703.11 CDJ53003.1 - 0.2 11.6 15.2 0.25 11.2 15.2 1.1 1 0 0 1 1 1 0 Auxin canalisation Pinin_SDK_memA PF04696.13 CDJ53003.1 - 0.22 11.6 33.6 0.3 11.1 33.6 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region BAF1_ABF1 PF04684.13 CDJ53003.1 - 0.35 9.9 18.5 0.4 9.7 18.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ53003.1 - 0.42 10.6 47.0 0.47 10.4 47.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FCP1_C PF09309.10 CDJ53003.1 - 0.7 9.7 16.4 0.83 9.5 16.4 1.1 1 0 0 1 1 1 0 FCP1, C-terminal GAGA_bind PF06217.12 CDJ53003.1 - 0.74 10.0 19.0 0.86 9.8 19.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family SLC12 PF03522.15 CDJ53003.1 - 0.83 8.6 19.9 0.91 8.5 19.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 HGTP_anticodon2 PF12745.7 CDJ53003.1 - 1 8.8 23.3 1.2 8.6 23.3 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Tim54 PF11711.8 CDJ53003.1 - 1 8.1 15.7 1.1 7.9 15.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 CDJ53003.1 - 1.1 8.7 19.3 1.3 8.4 19.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FAM60A PF15396.6 CDJ53003.1 - 1.3 9.0 12.4 1.6 8.7 12.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF3807 PF12720.7 CDJ53003.1 - 1.7 8.9 28.5 2.2 8.5 28.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2126 PF09899.9 CDJ53003.1 - 1.7 6.6 13.7 2.2 6.3 13.7 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) LTV PF04180.14 CDJ53003.1 - 1.8 8.2 18.0 2.1 8.0 18.0 1.0 1 0 0 1 1 1 0 Low temperature viability protein DUF3381 PF11861.8 CDJ53003.1 - 2.2 8.1 29.1 2.8 7.7 29.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Exonuc_VII_L PF02601.15 CDJ53003.1 - 2.2 7.8 23.0 2.6 7.5 23.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Draxin PF15550.6 CDJ53003.1 - 2.3 8.0 14.9 2.7 7.8 14.9 1.1 1 0 0 1 1 1 0 Draxin Med19 PF10278.9 CDJ53003.1 - 2.4 8.1 14.1 2.9 7.8 14.1 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF1387 PF07139.11 CDJ53003.1 - 2.5 7.8 20.7 2.9 7.5 20.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) ALMT PF11744.8 CDJ53003.1 - 2.6 6.8 16.9 3.1 6.5 16.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Membralin PF09746.9 CDJ53003.1 - 2.6 7.0 13.2 3 6.8 13.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF5568 PF17724.1 CDJ53003.1 - 2.6 7.8 11.6 3.1 7.6 11.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5568) CobT PF06213.12 CDJ53003.1 - 3 7.2 26.4 3.9 6.8 26.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cellulose_synt PF03552.14 CDJ53003.1 - 3.9 5.8 8.7 4.3 5.7 8.7 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF2052 PF09747.9 CDJ53003.1 - 4.1 7.5 21.2 4.9 7.2 21.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3292 PF11696.8 CDJ53003.1 - 4.4 5.5 14.8 5.1 5.3 14.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) PAT1 PF09770.9 CDJ53003.1 - 4.4 5.4 34.3 4.9 5.3 34.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PTPRCAP PF15713.5 CDJ53003.1 - 4.6 7.5 23.3 5.7 7.2 23.3 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 CDJ53003.1 - 4.6 5.4 18.1 5.3 5.2 18.1 1.0 1 0 0 1 1 1 0 CDC45-like protein PA26 PF04636.13 CDJ53003.1 - 4.7 6.0 15.3 5.3 5.9 15.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Band_3_cyto PF07565.13 CDJ53003.1 - 5.3 6.8 17.8 6.3 6.5 17.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ53003.1 - 5.6 5.6 26.1 6.5 5.4 26.1 1.0 1 0 0 1 1 1 0 Presenilin Peptidase_C58 PF03543.14 CDJ53003.1 - 6.5 6.4 27.6 8.6 6.0 27.6 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen NPR3 PF03666.13 CDJ53003.1 - 6.5 5.4 18.8 7.2 5.3 18.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CCSAP PF15748.5 CDJ53003.1 - 6.8 6.8 26.1 7.8 6.6 26.1 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated BORG_CEP PF14957.6 CDJ53003.1 - 7.1 7.8 12.2 8.7 7.5 12.2 1.2 1 0 0 1 1 1 0 Cdc42 effector Neur_chan_memb PF02932.16 CDJ53003.1 - 7.3 6.6 17.6 8.5 6.4 17.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.9 CDJ53003.1 - 7.4 6.6 17.1 9.2 6.3 17.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Atg14 PF10186.9 CDJ53003.1 - 7.9 5.5 23.2 9 5.3 23.2 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GREB1 PF15782.5 CDJ53003.1 - 10 3.1 22.2 11 2.9 22.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 CDJ53004.1 - 0.13 10.7 20.1 0.16 10.5 20.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF5131 PF07505.11 CDJ53004.1 - 0.22 11.0 12.0 0.6 9.5 12.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF5131) LMBR1 PF04791.16 CDJ53004.1 - 0.27 10.1 17.4 0.37 9.6 17.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 CDJ53004.1 - 0.31 9.8 18.1 0.39 9.4 18.1 1.2 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ53004.1 - 0.36 10.8 14.2 0.49 10.4 14.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4422 PF14393.6 CDJ53004.1 - 0.39 10.5 8.3 0.46 10.3 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) SLC12 PF03522.15 CDJ53004.1 - 0.47 9.4 21.8 0.52 9.3 21.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 V_ATPase_I PF01496.19 CDJ53004.1 - 0.48 8.3 22.3 0.55 8.1 22.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ABC2_membrane_3 PF12698.7 CDJ53004.1 - 0.88 8.6 8.8 1.2 8.2 8.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein CCSAP PF15748.5 CDJ53004.1 - 0.98 9.5 24.9 1.3 9.2 24.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated IF-2B PF01008.17 CDJ53004.1 - 1 8.5 11.4 1.3 8.2 11.4 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family PBP_dimer PF03717.15 CDJ53004.1 - 1.3 9.4 13.9 1.6 9.0 13.9 1.2 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain DDHD PF02862.17 CDJ53004.1 - 2.3 8.3 14.6 3.1 7.9 14.6 1.2 1 0 0 1 1 1 0 DDHD domain ALMT PF11744.8 CDJ53004.1 - 3.1 6.5 19.1 3.3 6.4 19.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter O-antigen_lig PF13425.6 CDJ53004.1 - 3.6 6.3 12.0 3.9 6.2 12.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Glyco_transf_41 PF13844.6 CDJ53004.1 - 5 5.4 18.7 6.1 5.2 18.7 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 Tyrosinase PF00264.20 CDJ53004.1 - 6.5 7.0 11.8 8.1 6.7 11.8 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase FapA PF03961.13 CDJ53004.1 - 8.4 4.9 19.1 13 4.3 19.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Methyltrn_RNA_4 PF09936.9 CDJ53004.1 - 9.8 6.0 11.8 12 5.7 11.8 1.1 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase tRNA-synt_1c PF00749.21 CDJ53005.1 - 6.7e-41 140.2 0.0 1.6e-23 83.1 0.0 4.8 4 2 1 5 5 5 2 tRNA synthetases class I (E and Q), catalytic domain SR-25 PF10500.9 CDJ53005.1 - 0.00017 21.2 12.2 0.00017 21.2 12.2 4.4 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein WD40 PF00400.32 CDJ53006.1 - 0.0013 19.6 0.3 0.0023 18.7 0.3 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat Spt20 PF12090.8 CDJ53006.1 - 0.0039 16.8 87.9 0.0069 16.0 12.7 3.3 3 0 0 3 3 3 2 Spt20 family BAF1_ABF1 PF04684.13 CDJ53006.1 - 0.016 14.3 25.2 0.19 10.8 13.6 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF5364 PF17322.2 CDJ53006.1 - 0.11 12.8 30.1 0.031 14.6 7.5 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5364) FAM176 PF14851.6 CDJ53006.1 - 0.25 11.0 19.2 0.15 11.8 2.5 3.2 3 0 0 3 3 3 0 FAM176 family PRC2_HTH_1 PF18118.1 CDJ53006.1 - 0.82 10.5 21.1 5 8.0 5.0 3.3 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain Dala_Dala_lig_N PF01820.21 CDJ53006.1 - 1.6 9.2 9.5 11 6.5 0.4 3.1 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus Band_3_cyto PF07565.13 CDJ53006.1 - 2 8.2 31.0 1.6 8.5 10.1 3.1 3 0 0 3 3 3 0 Band 3 cytoplasmic domain Afi1 PF07792.12 CDJ53006.1 - 4.6 7.7 28.6 6.8 7.2 1.3 3.1 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking AIF_C PF14721.6 CDJ53006.1 - 6.2 7.2 28.8 2.9 8.3 7.8 3.5 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Eapp_C PF10238.9 CDJ53006.1 - 6.8 6.8 34.9 0.52 10.4 7.5 3.2 3 0 0 3 3 3 0 E2F-associated phosphoprotein EIIBC-GUT_N PF03612.14 CDJ53006.1 - 7.3 6.3 36.5 0.45 10.2 4.0 3.2 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4834 PF16118.5 CDJ53006.1 - 7.8 7.5 45.2 0.63 11.0 3.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) rve PF00665.26 CDJ53008.1 - 1.6e-09 38.0 0.1 2.2e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain SecM PF06558.12 CDJ53008.1 - 0.022 14.8 0.3 0.048 13.8 0.1 1.5 2 0 0 2 2 2 0 Secretion monitor precursor protein (SecM) BSD PF03909.17 CDJ53009.1 - 2.8e-05 24.0 0.5 0.33 11.0 0.0 3.3 2 1 0 2 2 2 2 BSD domain Lin-8 PF03353.15 CDJ53010.1 - 0.0015 18.2 4.4 0.0015 18.2 4.4 6.7 4 2 1 5 5 5 2 Ras-mediated vulval-induction antagonist PLDc PF00614.22 CDJ53010.1 - 0.0017 18.5 0.4 1.4 9.3 0.0 2.3 2 0 0 2 2 2 2 Phospholipase D Active site motif SARAF PF06682.12 CDJ53011.1 - 0.0018 18.0 0.0 0.0018 18.0 0.0 7.2 2 2 2 5 5 5 1 SOCE-associated regulatory factor of calcium homoeostasis SUIM_assoc PF16619.5 CDJ53011.1 - 0.002 18.1 1.1 0.002 18.1 1.1 18.9 10 7 4 14 14 14 1 Unstructured region C-term to UIM in Ataxin3 OmpH PF03938.14 CDJ53012.1 - 0.11 12.8 15.6 0.19 12.1 15.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TFIIA PF03153.13 CDJ53012.1 - 0.13 12.2 38.0 0.067 13.2 23.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Shadoo PF14999.6 CDJ53013.1 - 0.007 16.5 2.2 0.007 16.5 2.2 2.3 2 0 0 2 2 2 1 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.19 CDJ53013.1 - 0.061 13.9 26.2 0.35 11.5 10.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chorion_S16 PF05836.12 CDJ53013.1 - 0.26 11.5 18.0 0.3 11.3 4.3 2.3 2 0 0 2 2 2 0 Chorion protein S16 RskA PF10099.9 CDJ53013.1 - 0.69 10.2 47.7 0.036 14.4 11.6 3.2 1 1 2 3 3 3 0 Anti-sigma-K factor rskA Med15 PF09606.10 CDJ53013.1 - 1.1 7.8 58.4 1.4 7.5 58.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3551 PF12071.8 CDJ53013.1 - 7.3 6.7 18.8 0.21 11.7 5.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3551) DUF2722 PF10846.8 CDJ53014.1 - 1.5e-06 27.4 2.5 1.5e-06 27.4 2.5 5.1 3 1 0 3 3 3 2 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ53014.1 - 0.00077 19.1 4.8 0.00077 19.1 4.8 4.5 4 1 0 4 4 4 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ53015.1 - 1.1e-05 25.2 30.2 0.0052 16.4 7.3 2.3 2 0 0 2 2 2 2 Spt20 family Presenilin PF01080.17 CDJ53015.1 - 0.0021 16.9 2.5 0.0026 16.6 2.5 1.3 1 0 0 1 1 1 1 Presenilin CPSF100_C PF13299.6 CDJ53015.1 - 0.037 14.2 3.7 2.5 8.3 1.6 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EPL1 PF10513.9 CDJ53015.1 - 0.97 9.8 10.7 8.2 6.8 0.3 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Suf PF05843.14 CDJ53015.1 - 4.7 7.1 18.5 3.7 7.4 6.9 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Pet20 PF08692.10 CDJ53015.1 - 6.2 7.6 5.6 9.7 6.9 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Ribosomal_60s PF00428.19 CDJ53017.1 - 0.36 11.5 10.6 0.57 10.8 10.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3138 PF11336.8 CDJ53017.1 - 0.71 8.4 3.7 0.6 8.7 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) LRR_6 PF13516.6 CDJ53018.1 - 4.4e-05 23.2 2.7 4.5 7.6 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 CDJ53018.1 - 0.00065 20.1 0.9 0.19 12.2 0.2 3.5 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ53018.1 - 0.002 17.8 9.0 2.8 7.8 0.0 4.2 3 1 0 3 3 3 3 Leucine rich repeat ABC_membrane PF00664.23 CDJ53020.1 - 5.3e-22 78.7 1.5 8.9e-22 78.0 1.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ53020.1 - 3.8e-12 46.9 0.4 7e-11 42.8 0.4 2.4 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ53020.1 - 3.7e-06 26.6 0.0 4.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF2722 PF10846.8 CDJ53020.1 - 0.00037 19.6 6.0 0.00037 19.6 6.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ53020.1 - 0.002 18.1 21.1 0.21 11.7 3.6 3.3 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Velvet PF11754.8 CDJ53020.1 - 0.0082 16.1 0.7 0.014 15.4 0.7 1.3 1 0 0 1 1 1 1 Velvet factor TFIIA PF03153.13 CDJ53020.1 - 0.13 12.2 24.3 1 9.3 4.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.13 CDJ53020.1 - 0.53 10.0 4.6 0.45 10.3 0.7 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Med15 PF09606.10 CDJ53020.1 - 1.9 7.1 26.0 0.031 13.0 6.3 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Coilin_N PF15862.5 CDJ53020.1 - 1.9 8.3 9.3 4.6 7.0 7.0 2.1 2 0 0 2 2 2 0 Coilin N-terminus Neur_chan_memb PF02932.16 CDJ53020.1 - 2.8 7.9 3.7 3.6 7.6 0.6 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Fmp27_SW PF10305.9 CDJ53020.1 - 3.2 8.5 9.2 0.058 14.1 2.0 1.8 2 0 0 2 2 1 0 RNA pol II promoter Fmp27 protein domain Pex14_N PF04695.13 CDJ53020.1 - 3.6 8.2 18.0 0.37 11.4 5.5 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ53020.1 - 8.3 6.3 11.8 3.2 7.7 4.5 2.4 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Caldesmon PF02029.15 CDJ53021.1 - 0.014 14.2 50.1 0.018 13.8 50.1 1.2 1 0 0 1 1 1 0 Caldesmon Pex14_N PF04695.13 CDJ53021.1 - 0.027 15.1 35.8 0.027 15.1 35.8 3.2 1 1 2 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Asp-B-Hydro_N PF05279.11 CDJ53021.1 - 0.043 13.9 44.2 0.06 13.4 44.2 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Nop14 PF04147.12 CDJ53021.1 - 0.072 11.3 38.7 0.086 11.1 38.7 1.2 1 0 0 1 1 1 0 Nop14-like family Dapper PF15268.6 CDJ53021.1 - 0.24 10.2 47.9 0.28 10.0 47.9 1.1 1 0 0 1 1 1 0 Dapper DUF4551 PF15087.6 CDJ53021.1 - 0.36 9.6 27.7 0.45 9.3 27.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOBP PF15279.6 CDJ53021.1 - 0.52 10.9 37.1 0.75 10.4 37.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein GREB1 PF15782.5 CDJ53021.1 - 1.3 6.1 43.0 1.4 6.0 43.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RRM_1 PF00076.22 CDJ53022.1 - 1.9e-14 53.2 0.0 2.2e-11 43.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ53022.1 - 1.6e-05 24.6 0.5 5.6e-05 22.9 0.0 2.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CDJ53022.1 - 0.00034 20.2 0.0 0.021 14.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CDJ53022.1 - 0.0091 16.2 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Calcipressin PF04847.12 CDJ53022.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Calcipressin RRM_3 PF08777.11 CDJ53022.1 - 0.04 14.0 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif AF-4 PF05110.13 CDJ53023.1 - 5 5.1 24.3 7.4 4.5 24.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Nop14 PF04147.12 CDJ53023.1 - 6.1 4.9 25.5 8 4.5 25.5 1.1 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 CDJ53023.1 - 7.7 5.5 15.8 11 5.0 15.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Seipin PF06775.14 CDJ53024.1 - 1.8e-09 38.0 0.1 0.00023 21.3 0.0 2.1 2 0 0 2 2 2 2 Putative adipose-regulatory protein (Seipin) RIO1 PF01163.22 CDJ53025.1 - 1.2e-46 158.7 0.1 2.9e-46 157.5 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CDJ53025.1 - 2.4e-33 114.2 1.5 5.6e-33 113.0 0.9 2.0 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 CDJ53025.1 - 3.6e-07 30.3 7.0 0.0012 18.8 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 CDJ53025.1 - 1.6e-06 27.6 0.2 3.6e-05 23.2 0.2 2.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3801 PF12687.7 CDJ53025.1 - 0.094 12.8 12.4 0.14 12.2 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Stork_head PF10264.9 CDJ53025.1 - 0.18 12.0 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Barttin PF15462.6 CDJ53025.1 - 4 7.2 11.4 6.4 6.5 11.4 1.3 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Pkinase_fungal PF17667.1 CDJ53025.1 - 10 4.8 8.9 0.62 8.8 0.1 2.3 2 0 0 2 2 2 0 Fungal protein kinase STI1 PF17830.1 CDJ53027.1 - 1.3e-06 28.2 2.7 0.00037 20.4 0.2 2.1 1 1 1 2 2 2 2 STI1 domain GerD PF17898.1 CDJ53027.1 - 0.0063 16.4 0.1 0.009 16.0 0.1 1.2 1 0 0 1 1 1 1 Spore germination GerD central core domain Nup96 PF12110.8 CDJ53027.1 - 0.05 12.7 0.0 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 ComC PF03047.14 CDJ53027.1 - 0.061 13.1 0.1 13 5.7 0.0 2.4 2 0 0 2 2 2 0 COMC family Glutaredoxin PF00462.24 CDJ53028.1 - 1.8e-16 60.1 0.0 2.4e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CDJ53028.1 - 0.00056 19.9 0.1 0.0016 18.5 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 CDJ53028.1 - 0.00065 20.1 0.1 0.0068 16.8 0.1 2.1 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 CDJ53028.1 - 0.0077 16.7 0.5 0.015 15.7 0.5 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.20 CDJ53028.1 - 0.031 14.0 0.2 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 CDJ53028.1 - 0.033 14.3 0.2 2.6 8.2 0.3 2.1 1 1 1 2 2 2 0 Thioredoxin FANCL_C PF11793.8 CDJ53028.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain TraF PF13728.6 CDJ53028.1 - 0.074 12.9 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CDJ53028.1 - 0.087 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DEAD PF00270.29 CDJ53029.1 - 1.4e-20 73.8 0.7 3.3e-20 72.6 0.7 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ53029.1 - 1.4e-17 64.1 0.1 1.2e-10 41.7 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDJ53029.1 - 1.9e-13 50.4 0.4 4.8e-13 49.1 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) RsgA_GTPase PF03193.16 CDJ53029.1 - 0.08 12.8 1.2 0.27 11.1 0.2 2.2 2 0 0 2 2 2 0 RsgA GTPase HTH_32 PF13565.6 CDJ53029.1 - 5.5 7.7 9.8 0.19 12.4 1.8 2.8 2 0 0 2 2 2 0 Homeodomain-like domain IMS PF00817.20 CDJ53030.1 - 2.1e-31 109.0 0.0 6.8e-31 107.3 0.0 1.9 1 1 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 CDJ53030.1 - 1.3e-06 28.7 0.0 9e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 CDJ53030.1 - 0.056 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif DDHD PF02862.17 CDJ53030.1 - 0.11 12.7 15.5 0.028 14.6 4.9 3.3 3 0 0 3 3 3 0 DDHD domain BRCT PF00533.26 CDJ53030.1 - 0.13 12.6 0.0 2.5 8.6 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDJ53030.1 - 0.2 11.7 0.0 0.42 10.6 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain PAT1 PF09770.9 CDJ53030.1 - 1.7 6.8 26.0 2.5 6.2 26.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ53030.1 - 2.1 8.4 13.3 1 9.3 8.7 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 CDJ53030.1 - 2.5 7.5 16.4 5.3 6.4 16.4 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ53030.1 - 3.5 6.5 18.3 5.3 5.9 18.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3464 PF11947.8 CDJ53030.1 - 6.4 6.5 14.6 25 4.6 14.6 2.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CnrY PF17524.2 CDJ53031.1 - 0.32 11.2 0.1 0.32 11.2 0.1 4.7 6 0 0 6 6 6 0 Anti-sigma factor CnrY ATP-synt_10 PF05176.14 CDJ53032.1 - 0.045 13.0 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 ATP10 protein Motilin_assoc PF04643.12 CDJ53033.1 - 0.086 12.7 2.5 82 3.2 0.1 4.1 4 0 0 4 4 4 0 Motilin/ghrelin-associated peptide DUF2722 PF10846.8 CDJ53034.1 - 0.0009 18.3 8.3 0.0009 18.3 8.3 4.1 2 1 1 3 3 2 1 Protein of unknown function (DUF2722) Ndc1_Nup PF09531.10 CDJ53034.1 - 0.0014 17.4 5.5 0.0014 17.4 5.5 2.3 2 0 0 2 2 2 2 Nucleoporin protein Ndc1-Nup Utp14 PF04615.13 CDJ53034.1 - 0.066 11.8 24.6 0.035 12.7 15.4 2.0 2 0 0 2 2 2 0 Utp14 protein RR_TM4-6 PF06459.12 CDJ53034.1 - 0.069 13.0 25.5 0.28 11.0 14.3 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 CDJ53034.1 - 0.22 10.3 9.8 0.64 8.8 4.5 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ53034.1 - 0.31 9.8 33.2 0.88 8.3 21.0 2.2 2 0 0 2 2 2 0 Presenilin PNISR PF15996.5 CDJ53034.1 - 0.49 10.6 37.7 2.4 8.4 3.9 2.4 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Endostatin PF06482.11 CDJ53034.1 - 0.64 9.4 22.3 1.4 8.3 8.9 2.4 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin DUF572 PF04502.13 CDJ53034.1 - 0.66 9.5 20.6 0.52 9.9 10.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) Otopetrin PF03189.13 CDJ53034.1 - 1.2 7.8 6.5 7.1 5.3 0.1 2.2 2 0 0 2 2 2 0 Otopetrin Neur_chan_memb PF02932.16 CDJ53034.1 - 2.8 7.9 22.7 2.7 8.0 2.4 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Raftlin PF15250.6 CDJ53034.1 - 4.1 6.1 26.6 0.46 9.2 15.2 2.3 2 0 0 2 2 2 0 Raftlin SAGA-Tad1 PF12767.7 CDJ53034.1 - 6 6.5 21.0 5.6 6.6 10.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit SLC12 PF03522.15 CDJ53034.1 - 6.5 5.7 26.8 4.9 6.1 2.4 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Hid1 PF12722.7 CDJ53034.1 - 7.9 4.5 30.1 1.8 6.6 18.3 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein BORCS6 PF10157.9 CDJ53035.1 - 0.3 11.3 6.6 0.25 11.6 1.1 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 FAM104 PF15434.6 CDJ53035.1 - 0.78 10.3 9.5 5.5 7.6 0.7 2.4 2 0 0 2 2 2 0 Family 104 PAP1 PF08601.10 CDJ53035.1 - 1.1 8.9 8.0 2.8 7.6 2.9 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 Histone_H2A_C PF16211.5 CDJ53037.1 - 5.1e-19 67.7 0.3 5.1e-19 67.7 0.3 1.8 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 CDJ53037.1 - 3.1e-15 56.7 0.0 4.1e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDJ53037.1 - 7e-05 23.0 0.0 9.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CobT PF06213.12 CDJ53038.1 - 0.0019 17.7 30.0 0.0019 17.7 30.0 5.3 3 2 2 5 5 5 1 Cobalamin biosynthesis protein CobT RskA PF10099.9 CDJ53038.1 - 0.064 13.5 0.0 0.064 13.5 0.0 5.7 1 1 4 5 5 5 0 Anti-sigma-K factor rskA Pkinase PF00069.25 CDJ53039.1 - 4.2e-51 173.8 0.0 2.5e-50 171.3 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ53039.1 - 3.9e-16 59.1 0.0 1.3e-15 57.4 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase Activator_LAG-3 PF11498.8 CDJ53039.1 - 1.6e-05 24.1 3.5 1.6e-05 24.1 3.5 6.1 5 1 1 6 6 6 2 Transcriptional activator LAG-3 APH PF01636.23 CDJ53039.1 - 0.18 11.7 0.0 0.18 11.7 0.0 7.5 4 3 1 7 7 7 0 Phosphotransferase enzyme family Ribosomal_L27A PF00828.19 CDJ53040.1 - 5.9e-22 78.7 0.1 7.6e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Tic110 PF16940.5 CDJ53041.1 - 9.5 4.6 12.2 11 4.3 12.2 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter SPX PF03105.19 CDJ53042.1 - 1.1 9.1 45.8 0.32 10.9 7.0 3.2 2 1 1 3 3 3 0 SPX domain AF-4 PF05110.13 CDJ53043.1 - 4.5e-06 25.1 20.2 4.5e-06 25.1 20.2 3.4 2 1 1 3 3 3 1 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ53043.1 - 0.00035 20.3 50.7 0.021 14.5 16.6 4.1 4 0 0 4 4 4 3 Nuclear RNA-splicing-associated protein DUF4692 PF15763.5 CDJ53043.1 - 0.011 16.3 4.5 0.011 16.3 4.5 4.2 4 1 0 4 4 4 0 Regulator of human erythroid cell expansion (RHEX) GPHR_N PF12537.8 CDJ53045.1 - 0.44 10.7 6.0 0.37 10.9 0.6 2.5 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal SpoIIP PF07454.11 CDJ53045.1 - 0.82 9.1 18.0 0.78 9.2 10.2 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) BORG_CEP PF14957.6 CDJ53045.1 - 1.4 10.1 12.5 6.3 8.0 7.4 2.2 2 0 0 2 2 2 0 Cdc42 effector FAM176 PF14851.6 CDJ53045.1 - 2.5 7.8 7.3 0.2 11.3 0.9 2.0 2 0 0 2 2 2 0 FAM176 family AIF_C PF14721.6 CDJ53045.1 - 5.6 7.3 15.5 0.55 10.6 5.8 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term V_ATPase_I PF01496.19 CDJ53045.1 - 7.1 4.4 20.9 1.8 6.4 9.7 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 CDJ53045.1 - 8.3 5.9 30.3 0.52 9.8 9.8 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit eIF-3_zeta PF05091.12 CDJ53045.1 - 9.7 5.0 26.0 0.63 9.0 10.7 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pro_isomerase PF00160.21 CDJ53046.1 - 2.3e-35 122.2 0.0 3.6e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 CDJ53046.1 - 6.1e-11 42.5 0.1 1.9e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 CDJ53046.1 - 1.9e-05 24.4 6.2 0.002 18.1 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ53046.1 - 0.00038 20.9 0.6 0.0084 16.6 0.4 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ53046.1 - 0.00077 19.2 3.2 0.16 11.9 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ53046.1 - 0.002 18.2 1.8 0.14 12.4 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ53046.1 - 0.0037 17.9 0.0 2 9.1 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ53046.1 - 0.01 15.5 2.3 5.9 6.7 0.1 3.3 3 0 0 3 3 3 0 TPR repeat DUF1645 PF07816.11 CDJ53047.1 - 9.2e-05 23.1 8.0 0.00011 22.9 8.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) Nha1_C PF08619.10 CDJ53047.1 - 0.0007 18.9 6.5 0.0008 18.7 6.5 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus AF-4 PF05110.13 CDJ53047.1 - 0.0033 15.6 20.7 0.0042 15.3 20.7 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein IMUP PF15761.5 CDJ53047.1 - 0.0062 17.2 11.0 0.0062 17.2 11.0 1.6 2 0 0 2 2 1 1 Immortalisation up-regulated protein TFIIA PF03153.13 CDJ53047.1 - 0.0092 16.0 15.2 0.012 15.7 15.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-L PF13092.6 CDJ53047.1 - 0.036 14.3 0.9 0.052 13.8 0.9 1.2 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 Spore_III_AF PF09581.10 CDJ53047.1 - 0.036 14.1 3.5 0.044 13.8 3.5 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Lin-8 PF03353.15 CDJ53047.1 - 0.043 13.4 16.8 0.073 12.6 16.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 CDJ53047.1 - 0.046 12.5 5.9 0.057 12.2 5.9 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 CDJ53047.1 - 0.17 10.4 12.0 0.22 10.1 12.0 1.0 1 0 0 1 1 1 0 Macoilin family DUF508 PF04370.12 CDJ53047.1 - 0.31 10.8 4.3 0.47 10.2 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) GREB1 PF15782.5 CDJ53047.1 - 0.34 8.0 12.0 0.39 7.8 12.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CDJ53047.1 - 0.5 9.7 6.7 0.65 9.4 6.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_S64 PF08192.11 CDJ53047.1 - 0.62 8.5 8.7 0.74 8.2 8.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.9 CDJ53047.1 - 0.68 8.1 13.0 0.76 8.0 13.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPX PF03105.19 CDJ53047.1 - 0.69 9.8 12.9 0.86 9.5 12.9 1.0 1 0 0 1 1 1 0 SPX domain V_ATPase_I PF01496.19 CDJ53047.1 - 1.1 7.0 3.6 1.3 6.9 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NST1 PF13945.6 CDJ53047.1 - 1.9 8.5 14.9 2.5 8.2 14.9 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator CCDC106 PF15794.5 CDJ53047.1 - 2.4 7.8 11.9 3.4 7.3 11.6 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 Pap_E4 PF02711.14 CDJ53047.1 - 3.2 8.8 15.2 7.6 7.6 5.2 2.2 1 1 1 2 2 2 0 E4 protein PCM1_C PF15717.5 CDJ53047.1 - 4 6.0 17.6 5.1 5.7 17.6 1.0 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus SLC12 PF03522.15 CDJ53047.1 - 4.9 6.1 7.8 5.8 5.8 7.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PAP1 PF08601.10 CDJ53047.1 - 5 6.7 17.2 6.3 6.4 17.2 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 CNOT1_TTP_bind PF16417.5 CDJ53047.1 - 5.5 6.1 12.8 7.8 5.6 12.8 1.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Apt1 PF10351.9 CDJ53047.1 - 6.3 5.5 12.3 8.3 5.1 12.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF755 PF05501.11 CDJ53047.1 - 7.4 6.9 28.3 0.13 12.6 12.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) RR_TM4-6 PF06459.12 CDJ53047.1 - 9.2 6.0 15.2 16 5.2 11.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 IMCp PF12314.8 CDJ53048.1 - 4e-17 62.3 49.2 1.3e-12 47.8 26.4 2.1 1 1 1 2 2 2 2 Inner membrane complex protein SUIM_assoc PF16619.5 CDJ53048.1 - 0.0012 18.8 4.2 0.0029 17.6 4.2 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ53048.1 - 0.05 13.6 8.2 0.084 12.9 8.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ53048.1 - 1.7 8.2 15.8 2.6 7.6 15.8 1.2 1 0 0 1 1 1 0 Spt20 family IMCp PF12314.8 CDJ53049.1 - 8.9e-27 93.2 57.5 4.6e-25 87.7 40.4 2.7 2 1 1 3 3 3 2 Inner membrane complex protein RT_RNaseH_2 PF17919.1 CDJ53050.1 - 2e-21 75.9 0.0 4.8e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ53050.1 - 1.7e-14 54.0 0.0 4e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ53050.1 - 3e-05 23.6 0.0 6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ53050.1 - 0.0081 16.3 0.1 0.026 14.7 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain Pex14_N PF04695.13 CDJ53052.1 - 0.00046 20.9 18.3 0.00046 20.9 18.3 9.0 5 2 1 7 7 7 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Otopetrin PF03189.13 CDJ53052.1 - 0.024 13.5 20.6 0.0097 14.8 8.1 3.8 2 1 0 2 2 2 0 Otopetrin TFIIA PF03153.13 CDJ53055.1 - 0.0019 18.3 57.1 0.011 15.8 30.7 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit tRNA-synt_2 PF00152.20 CDJ53056.1 - 4.9e-15 55.4 0.0 4.9e-15 55.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF4887 PF16228.5 CDJ53056.1 - 0.0027 17.9 23.5 0.0027 17.9 23.5 2.5 2 1 0 2 2 1 1 Domain of unknown function (DUF4887) Mitofilin PF09731.9 CDJ53056.1 - 0.018 13.9 19.7 0.024 13.5 19.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RskA PF10099.9 CDJ53056.1 - 0.024 14.9 11.5 0.17 12.1 11.5 2.2 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Borrelia_P83 PF05262.11 CDJ53056.1 - 0.072 11.6 17.9 0.1 11.1 17.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 CDJ53056.1 - 0.25 10.6 11.8 0.34 10.2 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 CDJ53056.1 - 0.56 10.0 17.8 0.86 9.4 17.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.8 CDJ53056.1 - 0.97 8.5 32.9 2 7.5 32.9 1.4 1 0 0 1 1 1 0 SprA-related family eIF-3_zeta PF05091.12 CDJ53056.1 - 1.1 8.2 16.8 1.5 7.7 16.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 CDJ53056.1 - 1.4 8.5 35.0 0.86 9.2 27.6 2.3 2 0 0 2 2 2 0 Spt20 family CDC45 PF02724.14 CDJ53056.1 - 2.1 6.5 16.9 2.9 6.1 16.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DDRGK PF09756.9 CDJ53056.1 - 2.6 7.6 21.0 4.6 6.8 21.0 1.3 1 0 0 1 1 1 0 DDRGK domain PPP4R2 PF09184.11 CDJ53056.1 - 2.6 7.6 22.1 1.2 8.6 20.0 1.4 1 1 0 1 1 1 0 PPP4R2 PA26 PF04636.13 CDJ53056.1 - 4.2 6.2 12.7 6.1 5.6 12.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Cohesin_HEAT PF12765.7 CDJ53057.1 - 0.027 14.8 1.6 2.8 8.3 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Actin PF00022.19 CDJ53058.1 - 2.7e-144 480.8 0.0 1.2e-143 478.6 0.0 1.7 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 CDJ53059.1 - 6.5e-49 166.7 0.0 9e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ53059.1 - 1.1e-42 146.1 0.0 1.5e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ53059.1 - 0.0082 15.1 0.2 0.016 14.2 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CDJ53059.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CDJ53059.1 - 0.055 12.8 0.2 0.099 12.0 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ53059.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ53059.1 - 0.09 11.5 0.4 3.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 CDJ53059.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like NPF PF16601.5 CDJ53060.1 - 0.034 14.6 0.7 0.05 14.1 0.7 1.3 1 0 0 1 1 1 0 Rabosyn-5 repeating NPF sequence-motif MMR_HSR1 PF01926.23 CDJ53061.1 - 2.8e-13 49.9 0.0 1.2e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 CDJ53061.1 - 0.00014 21.3 0.0 0.00049 19.5 0.0 1.9 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.18 CDJ53061.1 - 0.0002 20.9 0.0 0.00082 18.9 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RELT PF12606.8 CDJ53061.1 - 0.037 13.0 2.0 0.068 12.2 2.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Septin PF00735.18 CDJ53061.1 - 0.05 12.9 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.23 CDJ53061.1 - 0.051 13.6 0.2 0.34 11.0 0.0 2.1 1 1 1 2 2 2 0 Dynamin family Med21 PF11221.8 CDJ53062.1 - 1e-11 45.3 0.0 1.4e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GCN5L1 PF06320.13 CDJ53062.1 - 0.0014 18.8 2.0 0.0019 18.3 2.0 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Serine_rich PF08824.10 CDJ53062.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain APG6_N PF17675.1 CDJ53062.1 - 0.054 14.0 4.4 0.074 13.6 4.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Viral_P18 PF04521.13 CDJ53062.1 - 0.07 12.9 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Ubiq_cyt_C_chap PF03981.12 CDJ53063.1 - 4.2e-08 33.4 0.0 2.7e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Metaviral_G PF09595.10 CDJ53064.1 - 0.04 14.0 0.2 0.092 12.8 0.2 1.5 1 0 0 1 1 1 0 Metaviral_G glycoprotein ABM PF03992.16 CDJ53065.1 - 0.11 12.6 0.2 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase AAA_6 PF12774.7 CDJ53066.1 - 2.6e-144 480.2 0.0 2.1e-139 464.1 0.0 4.0 4 0 0 4 4 4 2 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CDJ53066.1 - 8.9e-92 307.1 0.0 8.6e-90 300.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 CDJ53066.1 - 8.5e-88 295.1 16.4 8.5e-88 295.1 16.4 4.5 3 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 MT PF12777.7 CDJ53066.1 - 1.3e-77 261.2 14.4 2.8e-77 260.1 14.4 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 CDJ53066.1 - 1.9e-73 247.4 1.7 9.3e-72 241.8 0.0 3.7 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CDJ53066.1 - 1.8e-63 213.3 0.6 1.4e-59 200.6 0.0 3.7 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_9 PF12781.7 CDJ53066.1 - 1.8e-55 187.5 1.8 7.1e-55 185.5 1.7 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 CDJ53066.1 - 1.2e-47 161.8 0.0 3.3e-47 160.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ53066.1 - 1.1e-27 96.5 0.0 8.1e-26 90.5 0.0 3.3 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CDJ53066.1 - 4.2e-23 81.9 0.0 2.9e-10 40.3 0.0 6.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDJ53066.1 - 2.8e-19 69.5 0.3 6.4e-18 65.1 0.1 3.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ53066.1 - 3e-19 69.1 0.0 2.6e-18 66.1 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain Kelch_5 PF13854.6 CDJ53066.1 - 2.5e-11 43.3 0.4 5e-06 26.4 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 CDJ53066.1 - 2e-10 40.7 11.6 1.8e-05 24.9 0.2 4.7 5 0 0 5 5 4 2 Galactose oxidase, central domain Filamin PF00630.19 CDJ53066.1 - 3.9e-10 40.5 0.0 9.7e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat Kelch_1 PF01344.25 CDJ53066.1 - 1.4e-09 37.4 5.2 1.5e-05 24.4 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CDJ53066.1 - 1e-08 35.0 3.4 3e-05 23.9 0.1 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain AAA_16 PF13191.6 CDJ53066.1 - 6.2e-08 33.2 0.3 0.73 10.2 0.0 6.3 5 0 0 5 5 5 1 AAA ATPase domain Kelch_6 PF13964.6 CDJ53066.1 - 2.6e-07 30.7 4.5 0.0057 16.9 0.1 4.1 4 0 0 4 4 3 2 Kelch motif AAA PF00004.29 CDJ53066.1 - 5.2e-06 26.9 0.1 0.42 11.1 0.0 4.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDJ53066.1 - 7.5e-06 26.5 0.3 0.9 10.1 0.0 4.4 4 0 0 4 4 3 2 AAA domain TIG PF01833.24 CDJ53066.1 - 8.6e-06 25.7 0.2 2e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 IPT/TIG domain AAA_22 PF13401.6 CDJ53066.1 - 1.8e-05 25.0 5.0 0.26 11.6 0.0 5.2 5 0 0 5 5 4 1 AAA domain AAA_33 PF13671.6 CDJ53066.1 - 0.0005 20.3 0.1 11 6.2 0.0 4.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CDJ53066.1 - 0.00095 19.5 0.3 16 6.0 0.0 4.4 4 0 0 4 4 4 0 RNA helicase AAA_30 PF13604.6 CDJ53066.1 - 0.023 14.4 0.2 16 5.2 0.0 3.9 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 CDJ53066.1 - 0.048 13.4 0.0 4.2 7.1 0.0 3.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CDJ53066.1 - 0.048 13.4 1.4 10 5.8 0.0 3.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 CDJ53066.1 - 0.07 12.8 0.0 14 5.3 0.0 3.5 4 0 0 4 4 3 0 Sigma-54 interaction domain MeaB PF03308.16 CDJ53066.1 - 0.14 11.1 0.0 0.96 8.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4094 PF13334.6 CDJ53066.1 - 0.17 12.3 1.2 1.3 9.5 0.1 3.2 2 0 0 2 2 1 0 Domain of unknown function (DUF4094) Kelch_2 PF07646.15 CDJ53066.1 - 0.54 10.3 4.8 1.4 9.0 0.1 3.3 3 0 0 3 3 3 0 Kelch motif AAA_19 PF13245.6 CDJ53066.1 - 0.68 10.3 5.4 13 6.1 0.0 4.4 4 1 0 4 4 3 0 AAA domain ABC_tran PF00005.27 CDJ53066.1 - 1.7 9.2 5.4 9.2 6.8 0.0 3.9 4 0 0 4 4 2 0 ABC transporter Orbi_VP5 PF00901.17 CDJ53066.1 - 2.2 6.6 5.8 0.22 9.9 0.5 1.9 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 Abhydrolase_6 PF12697.7 CDJ53067.1 - 5.9e-23 82.6 0.1 1.1e-22 81.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ53067.1 - 2.6e-08 33.4 0.3 2.4e-07 30.3 0.3 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ53067.1 - 5.6e-08 32.7 0.0 2.6e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 CDJ53067.1 - 0.00033 20.5 0.2 0.00054 19.7 0.0 1.4 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.7 CDJ53067.1 - 0.014 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 CDJ53067.1 - 0.027 14.3 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 CDJ53067.1 - 0.029 14.5 0.1 0.18 11.9 0.0 2.2 3 0 0 3 3 3 0 Thioesterase domain DEAD PF00270.29 CDJ53068.1 - 2.9e-25 89.0 0.0 5.1e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ53068.1 - 2.7e-22 79.2 0.0 5.1e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ53068.1 - 0.14 12.4 0.0 0.74 10.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF4199 PF13858.6 CDJ53069.1 - 0.18 12.2 6.2 4.5 7.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) E1-E2_ATPase PF00122.20 CDJ53070.1 - 2.1e-25 89.3 20.4 1.8e-24 86.2 0.1 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 CDJ53070.1 - 1.9e-17 64.3 3.6 5.4e-06 26.9 0.7 4.7 4 1 0 4 4 4 3 haloacid dehalogenase-like hydrolase HMA PF00403.26 CDJ53070.1 - 1e-09 38.7 0.0 2.7e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CDJ53070.1 - 0.24 11.1 0.1 3.7 7.2 0.0 2.4 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF3974 PF13120.6 CDJ53071.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3974) RskA PF10099.9 CDJ53073.1 - 4e-06 27.2 39.7 0.00019 21.8 23.1 10.6 1 1 8 9 9 9 5 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ53073.1 - 0.00014 21.6 20.0 0.00014 21.6 20.0 8.3 4 3 3 7 7 7 2 Nuclear RNA-splicing-associated protein DnaJ PF00226.31 CDJ53074.1 - 1.1e-13 51.1 0.7 2.2e-13 50.1 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 CDJ53074.1 - 1.4e-11 44.3 0.0 2.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin SUIM_assoc PF16619.5 CDJ53074.1 - 0.0017 18.4 0.6 0.003 17.6 0.6 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ53076.1 - 0.00074 18.6 5.2 0.00074 18.6 5.2 11.2 8 2 3 11 11 11 2 Protein of unknown function (DUF2722) BAF1_ABF1 PF04684.13 CDJ53076.1 - 0.00083 18.5 15.1 0.00083 18.5 15.1 6.5 7 1 0 7 7 7 2 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ53076.1 - 0.005 16.9 23.9 0.005 16.9 23.9 8.5 4 2 4 9 9 9 1 Transcription factor IIA, alpha/beta subunit DUF4207 PF13904.6 CDJ53077.1 - 0.0016 18.2 8.4 0.0016 18.2 8.4 5.3 7 0 0 7 7 7 2 Domain of unknown function (DUF4207) SPX PF03105.19 CDJ53077.1 - 0.0052 16.8 3.0 0.0052 16.8 3.0 4.1 2 1 1 4 4 4 1 SPX domain Spt20 PF12090.8 CDJ53077.1 - 0.098 12.3 46.4 0.012 15.2 10.7 3.6 3 0 0 3 3 3 0 Spt20 family MecA PF05389.12 CDJ53077.1 - 0.59 9.7 3.7 13 5.3 0.2 2.7 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) HNOBA PF07701.14 CDJ53077.1 - 2.2 7.7 8.2 11 5.4 0.3 2.8 2 0 0 2 2 2 0 Heme NO binding associated BBS2_N PF14781.6 CDJ53077.1 - 3.2 7.7 5.6 4 7.4 0.1 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal TYW3 PF02676.14 CDJ53077.1 - 5.4 6.3 6.4 1.2 8.5 1.1 2.3 2 0 0 2 2 2 0 Methyltransferase TYW3 Apt1 PF10351.9 CDJ53077.1 - 9.5 4.9 27.6 9.8 4.9 8.3 3.6 2 1 0 2 2 2 0 Golgi-body localisation protein domain DUF4667 PF15700.5 CDJ53078.1 - 0.0052 16.9 14.9 1.9 8.5 1.7 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ53078.1 - 0.0065 16.1 9.8 0.0065 16.1 9.8 1.8 2 0 0 2 2 2 1 Spt20 family DUF3446 PF11928.8 CDJ53078.1 - 0.0095 16.2 7.1 0.0095 16.2 7.1 5.2 5 1 0 5 5 5 2 Early growth response N-terminal domain SPX PF03105.19 CDJ53078.1 - 0.071 13.0 9.4 0.23 11.3 6.1 2.3 2 0 0 2 2 2 0 SPX domain Presenilin PF01080.17 CDJ53078.1 - 1.1 7.9 4.7 2.7 6.7 4.7 1.7 1 0 0 1 1 1 0 Presenilin MID_MedPIWI PF18296.1 CDJ53078.1 - 1.3 8.8 8.2 15 5.3 4.2 3.0 3 0 0 3 3 3 0 MID domain of medPIWI TERB2 PF15101.6 CDJ53078.1 - 2.1 8.4 9.7 9.2 6.3 0.0 2.8 3 0 0 3 3 3 0 Telomere-associated protein TERB2 SR-25 PF10500.9 CDJ53078.1 - 2.4 7.7 40.7 0.076 12.6 7.0 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.9 CDJ53078.1 - 9.6 4.3 12.6 13 3.9 12.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ53079.1 - 0.067 11.5 21.4 0.12 10.7 21.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.9 CDJ53079.1 - 1.4 7.4 12.1 1.9 6.9 12.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator VIR_N PF15912.5 CDJ53079.1 - 1.5 8.4 15.7 0.023 14.3 8.4 1.7 2 0 0 2 2 2 0 Virilizer, N-terminal zf-C2H2 PF00096.26 CDJ53079.1 - 1.9 9.1 5.5 3.5 8.3 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type TLP-20 PF06088.11 CDJ53079.1 - 4.3 7.2 12.4 9.6 6.1 12.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4045 PF13254.6 CDJ53079.1 - 4.4 6.9 27.7 0.73 9.4 15.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) RtcB PF01139.17 CDJ53080.1 - 1.3e-31 110.3 0.0 1.5e-31 110.0 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Cu-oxidase_4 PF02578.15 CDJ53080.1 - 0.064 12.8 0.6 0.11 12.1 0.3 1.4 1 1 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase EcoRII-C PF09019.11 CDJ53081.1 - 1.7 8.7 17.6 5.7 7.0 0.9 4.1 1 1 3 4 4 4 0 EcoRII C terminal WD40 PF00400.32 CDJ53083.1 - 1.4e-11 44.7 0.9 0.00056 20.7 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ53083.1 - 4.6e-08 33.3 0.0 0.002 18.4 0.0 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain CHAP PF05257.16 CDJ53083.1 - 0.12 12.9 0.1 0.27 11.8 0.1 1.6 1 1 0 1 1 1 0 CHAP domain Dynamin_M PF01031.20 CDJ53084.1 - 1.3e-12 47.5 3.1 8.4e-12 44.9 0.1 2.7 2 1 1 3 3 3 1 Dynamin central region DUF4726 PF15855.5 CDJ53084.1 - 0.0018 18.5 1.4 0.0018 18.5 1.4 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4726) MPM1 PF17234.2 CDJ53084.1 - 0.0045 17.3 0.8 0.0067 16.7 0.8 1.3 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 SOSSC PF15925.5 CDJ53084.1 - 0.0085 17.4 0.3 0.11 13.8 1.0 2.2 2 0 0 2 2 2 1 SOSS complex subunit C GED PF02212.18 CDJ53084.1 - 0.15 12.2 4.6 0.22 11.7 0.1 3.0 3 0 0 3 3 3 0 Dynamin GTPase effector domain CHASE3 PF05227.13 CDJ53084.1 - 5.3 7.0 15.4 9 6.2 11.9 2.7 1 1 2 3 3 3 0 CHASE3 domain DUF4667 PF15700.5 CDJ53085.1 - 0.22 11.6 7.3 0.24 11.5 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) SR-25 PF10500.9 CDJ53085.1 - 0.3 10.6 22.3 0.35 10.4 22.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ53085.1 - 0.49 10.7 11.6 0.62 10.4 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AF-4 PF05110.13 CDJ53085.1 - 1.5 6.8 18.8 1.8 6.6 18.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PAP1 PF08601.10 CDJ53085.1 - 2.1 8.0 12.0 2 8.0 12.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.9 CDJ53085.1 - 2.3 7.0 4.4 2.4 6.9 4.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mitofilin PF09731.9 CDJ53085.1 - 5.1 5.8 15.6 5.4 5.7 15.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.9 CDJ53085.1 - 6.5 5.2 9.8 8.7 4.8 9.8 1.2 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CDJ53085.1 - 8.2 3.4 6.7 8.8 3.3 6.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peroxin-3 PF04882.12 CDJ53085.1 - 9.5 5.1 8.8 10 5.0 8.8 1.0 1 0 0 1 1 1 0 Peroxin-3 zf-RanBP PF00641.18 CDJ53087.1 - 3e-06 26.4 5.2 3e-06 26.4 5.2 2.1 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Spt20 PF12090.8 CDJ53087.1 - 0.0049 16.5 21.9 0.0049 16.5 21.9 11.7 5 3 2 8 8 8 1 Spt20 family Coilin_N PF15862.5 CDJ53087.1 - 0.39 10.5 0.0 0.39 10.5 0.0 10.4 10 1 1 11 11 11 0 Coilin N-terminus RskA PF10099.9 CDJ53088.1 - 0.0004 20.7 18.7 0.0004 20.7 18.7 2.0 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Form-deh_trans PF09163.11 CDJ53088.1 - 0.14 12.0 0.7 0.14 12.0 0.7 1.7 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane DUF4712 PF15830.5 CDJ53088.1 - 0.42 10.3 5.6 0.49 10.0 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) IER PF05760.12 CDJ53088.1 - 3.4 7.9 21.0 4.8 7.4 21.0 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF4834 PF16118.5 CDJ53088.1 - 4.8 8.2 11.2 7 7.7 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2457 PF10446.9 CDJ53088.1 - 8.8 5.3 11.1 10 5.1 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SR-25 PF10500.9 CDJ53089.1 - 0.23 11.1 42.4 0.047 13.3 24.0 2.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF5423 PF17461.2 CDJ53090.1 - 0.051 12.4 8.1 0.067 12.0 8.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Rtf2 PF04641.12 CDJ53090.1 - 0.76 9.1 19.9 0.91 8.8 19.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger SLC12 PF03522.15 CDJ53090.1 - 1.3 7.9 20.5 1.6 7.6 20.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Raftlin PF15250.6 CDJ53090.1 - 1.5 7.5 21.9 1.7 7.3 21.9 1.0 1 0 0 1 1 1 0 Raftlin Dsh_C PF12316.8 CDJ53090.1 - 3.8 7.9 18.2 5.2 7.4 18.2 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CDC45 PF02724.14 CDJ53090.1 - 4.9 5.3 21.6 6 5.0 21.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3446 PF11928.8 CDJ53090.1 - 5.7 7.3 11.5 0.14 12.5 4.8 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF3712 PF12505.8 CDJ53091.1 - 1.5e-09 38.2 0.6 0.1 12.9 0.0 5.7 5 0 0 5 5 5 3 Protein of unknown function (DUF3712) SPX PF03105.19 CDJ53091.1 - 0.00053 20.0 18.8 0.00053 20.0 18.8 7.1 6 2 0 6 6 6 2 SPX domain CNDH2_C PF16858.5 CDJ53091.1 - 0.005 16.8 2.0 0.005 16.8 2.0 4.9 4 1 0 4 4 4 2 Condensin II complex subunit CAP-H2 or CNDH2, C-term Androgen_recep PF02166.16 CDJ53092.1 - 3.5 6.4 15.2 3.8 6.3 15.2 1.0 1 0 0 1 1 1 0 Androgen receptor DUF3138 PF11336.8 CDJ53092.1 - 5.1 5.6 11.8 5.4 5.5 11.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spt20 PF12090.8 CDJ53094.1 - 0.0018 17.9 20.6 0.051 13.2 9.1 2.2 2 0 0 2 2 2 2 Spt20 family BK_channel_a PF03493.18 CDJ53094.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit SUIM_assoc PF16619.5 CDJ53094.1 - 0.21 11.7 21.3 0.64 10.1 1.7 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Neur_chan_memb PF02932.16 CDJ53094.1 - 5.1 7.1 5.7 53 3.8 4.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region NST1 PF13945.6 CDJ53094.1 - 8.3 6.5 12.3 5.8 7.0 7.0 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator Bud13 PF09736.9 CDJ53095.1 - 3.2 8.1 11.2 5 7.5 11.2 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex SR-25 PF10500.9 CDJ53096.1 - 2.7e-05 23.9 19.1 2.7e-05 23.9 19.1 2.4 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Velvet PF11754.8 CDJ53096.1 - 0.03 14.3 33.0 0.027 14.4 13.7 2.2 2 0 0 2 2 2 0 Velvet factor DUF3523 PF12037.8 CDJ53096.1 - 2 7.7 50.9 1.2 8.5 16.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) TCP PF03634.13 CDJ53096.1 - 2 9.0 47.8 1.1 9.8 19.7 2.7 2 1 0 2 2 2 0 TCP family transcription factor SOBP PF15279.6 CDJ53096.1 - 2.1 8.9 33.6 0.056 14.0 11.2 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein Presenilin PF01080.17 CDJ53096.1 - 2.8 6.6 51.6 0.12 11.1 21.2 2.2 2 0 0 2 2 2 0 Presenilin SpoIIP PF07454.11 CDJ53096.1 - 2.8 7.3 39.0 0.16 11.4 13.5 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) FmiP_Thoc5 PF09766.9 CDJ53096.1 - 3.2 6.9 37.8 2.7 7.2 10.4 2.5 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Tim54 PF11711.8 CDJ53096.1 - 3.5 6.3 32.7 1.3 7.7 12.6 2.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF2052 PF09747.9 CDJ53099.1 - 0.54 10.4 21.7 0.7 10.0 18.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Neur_chan_memb PF02932.16 CDJ53099.1 - 9.5 6.2 20.6 12 5.9 17.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.9 CDJ53100.1 - 0.0016 18.1 39.0 0.0016 18.1 39.0 15.6 8 5 6 14 14 14 6 Nuclear RNA-splicing-associated protein Adeno_PIX PF03955.14 CDJ53101.1 - 0.43 10.8 8.4 0.62 10.3 8.4 1.2 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) RskA PF10099.9 CDJ53102.1 - 0.053 13.8 24.3 0.041 14.2 16.1 2.5 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ53102.1 - 1.3 9.6 17.2 4.7 7.9 17.2 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-RING_2 PF13639.6 CDJ53104.1 - 3.3e-05 24.1 13.7 3.3e-05 24.1 13.7 3.1 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ53104.1 - 0.00027 20.8 14.2 0.00027 20.8 14.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 CDJ53104.1 - 0.0013 19.4 13.5 0.013 16.2 6.6 4.0 2 1 3 5 5 5 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 CDJ53104.1 - 0.002 17.9 12.8 0.002 17.9 12.8 2.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 CDJ53104.1 - 0.0038 17.2 3.6 0.0038 17.2 3.6 4.5 1 1 5 6 6 6 4 Seven in absentia protein family zf-C3HC4_4 PF15227.6 CDJ53104.1 - 0.0051 16.9 12.5 0.022 14.9 12.5 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CDJ53104.1 - 0.011 15.7 5.2 0.011 15.7 5.2 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CDJ53104.1 - 0.011 15.7 13.5 0.011 15.7 13.5 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-TRAF_2 PF15965.5 CDJ53104.1 - 3.1 8.3 26.0 0.13 12.7 5.1 3.4 2 1 2 4 4 4 0 TRAF-like zinc-finger OTU PF02338.19 CDJ53105.1 - 1.6e-11 44.8 0.0 2.7e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease RNA_pol_Rpb2_45 PF10385.9 CDJ53108.1 - 0.076 13.3 0.3 0.17 12.2 0.3 1.5 1 0 0 1 1 1 0 RNA polymerase beta subunit external 1 domain OrfB_IS605 PF01385.19 CDJ53108.1 - 0.29 11.4 7.6 0.51 10.6 0.6 2.3 2 0 0 2 2 2 0 Probable transposase Rol_Rep_N PF18106.1 CDJ53108.1 - 0.33 11.3 1.1 0.54 10.6 0.1 1.7 2 0 0 2 2 2 0 Rolling Circle replication initiation protein N-terminal domain YabA PF06156.13 CDJ53108.1 - 0.62 10.7 10.4 0.14 12.8 5.8 2.0 2 0 0 2 2 2 0 Initiation control protein YabA V_ATPase_I PF01496.19 CDJ53108.1 - 5.9 4.7 7.2 4.3 5.1 6.0 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ParA PF10609.9 CDJ53109.1 - 3.8e-68 229.6 0.0 8.8e-47 159.6 0.0 2.1 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 CDJ53109.1 - 2.2e-13 50.2 0.0 7.1e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 CDJ53109.1 - 3.6e-12 46.4 0.0 5.1e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CDJ53109.1 - 6.1e-07 29.5 0.1 1.6e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF971 PF06155.12 CDJ53109.1 - 7e-06 26.6 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) MipZ PF09140.11 CDJ53109.1 - 8.8e-06 25.2 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CDJ53109.1 - 0.0025 17.1 0.5 0.33 10.1 0.3 2.2 2 0 0 2 2 2 2 Anion-transporting ATPase VirC1 PF07015.11 CDJ53109.1 - 0.0037 16.6 0.1 0.0065 15.8 0.1 1.3 1 0 0 1 1 1 1 VirC1 protein MeaB PF03308.16 CDJ53109.1 - 0.043 12.8 0.1 0.073 12.0 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 CDJ53109.1 - 0.044 13.7 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CLP1_P PF16575.5 CDJ53109.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 CDJ53109.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IMCp PF12314.8 CDJ53110.1 - 1.6e-24 86.0 23.2 1.6e-24 86.0 23.2 3.8 1 1 2 3 3 3 3 Inner membrane complex protein ATP-synt_C PF00137.21 CDJ53111.1 - 7.1e-30 103.1 32.4 2.7e-16 59.6 11.1 2.4 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 CDJ53111.1 - 0.17 12.3 0.1 0.3 11.5 0.1 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 ASH PF15780.5 CDJ53112.1 - 5.7e-55 183.6 28.3 1.1e-06 28.8 0.0 21.8 23 1 1 24 24 24 11 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CDJ53112.1 - 1.2e-23 83.2 5.0 0.022 14.9 0.0 15.4 16 0 0 16 16 16 3 Flagellar-associated PapD-like DUF1573 PF07610.11 CDJ53112.1 - 8.3e-18 64.2 0.2 0.95 9.5 0.0 15.3 17 1 0 17 17 17 4 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 CDJ53112.1 - 4.3e-09 36.5 13.2 0.07 13.4 0.0 10.6 12 0 0 12 12 12 3 Transmembrane protein 131-like Motile_Sperm PF00635.26 CDJ53112.1 - 9.3e-09 35.1 1.1 0.081 12.8 0.0 9.4 12 0 0 12 12 12 2 MSP (Major sperm protein) domain MYCBPAP PF14646.6 CDJ53112.1 - 4.4e-07 29.2 1.4 4.8 6.0 0.0 7.9 8 1 1 9 9 9 2 MYCBP-associated protein family FixG_C PF11614.8 CDJ53112.1 - 3e-05 24.2 0.2 15 5.9 0.0 7.3 8 0 0 8 8 8 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Big_5 PF13205.6 CDJ53112.1 - 0.66 10.7 5.3 78 4.0 0.1 6.3 8 0 0 8 8 8 0 Bacterial Ig-like domain cEGF PF12662.7 CDJ53113.1 - 1.5e-07 31.2 32.1 0.015 15.2 0.7 7.3 7 0 0 7 7 7 4 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDJ53113.1 - 0.022 15.0 3.4 0.022 15.0 3.4 8.0 8 1 0 8 8 8 0 Coagulation Factor Xa inhibitory site RANK_CRD_2 PF18278.1 CDJ53113.1 - 0.043 14.0 22.7 0.11 12.7 0.2 5.6 5 1 1 6 6 6 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Creatinase_N_2 PF16189.5 CDJ53114.1 - 3.1e-33 115.1 0.0 7e-32 110.8 0.0 2.7 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CDJ53114.1 - 1.1e-25 90.5 0.3 1.3e-24 87.1 0.3 2.4 1 1 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CDJ53114.1 - 4e-25 87.7 2.9 4.9e-25 87.4 0.0 2.7 4 0 0 4 4 4 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CDJ53114.1 - 5.7e-21 75.5 0.0 9.3e-16 58.7 0.0 2.8 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain zf-U1 PF06220.12 CDJ53115.1 - 0.00025 20.7 0.5 0.00045 19.9 0.5 1.4 1 0 0 1 1 1 1 U1 zinc finger WW PF00397.26 CDJ53115.1 - 0.069 13.3 1.6 0.071 13.2 0.0 1.9 2 0 0 2 2 2 0 WW domain Ribosomal_S2 PF00318.20 CDJ53115.1 - 3.5 6.8 10.3 0.064 12.5 1.6 2.1 2 0 0 2 2 2 0 Ribosomal protein S2 Penicil_amidase PF01804.18 CDJ53116.1 - 5.5e-122 409.0 0.0 6.4e-122 408.8 0.0 1.0 1 0 0 1 1 1 1 Penicillin amidase ABC1 PF03109.16 CDJ53117.1 - 1.2e-32 112.5 0.0 2.6e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CDJ53117.1 - 0.072 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Ribonuc_P_40 PF08584.11 CDJ53118.1 - 6.8e-06 25.6 0.0 1.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit SbcCD_C PF13558.6 CDJ53119.1 - 4.5e-06 26.8 0.0 1.3e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 CDJ53119.1 - 5.6e-06 26.4 0.7 0.0021 17.9 0.2 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Metallophos PF00149.28 CDJ53119.1 - 1.7e-05 25.4 0.0 4.3e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AAA_23 PF13476.6 CDJ53119.1 - 3.9e-05 24.2 0.0 6.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 CDJ53119.1 - 0.00058 19.3 0.0 0.59 9.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 CDJ53119.1 - 0.018 15.6 0.2 6.3 7.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter MukB PF04310.12 CDJ53119.1 - 0.045 13.6 0.2 0.083 12.7 0.2 1.3 1 0 0 1 1 1 0 MukB N-terminal AAA_15 PF13175.6 CDJ53119.1 - 0.051 13.3 0.0 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CDJ53119.1 - 0.071 12.9 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_2 PF07719.17 CDJ53120.1 - 6.5e-15 54.0 8.3 0.00068 19.6 0.0 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ53120.1 - 6.7e-14 51.0 3.1 0.00039 20.1 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ53120.1 - 8.1e-12 44.4 0.5 0.042 14.1 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ53120.1 - 2.5e-10 40.3 3.1 0.017 15.9 0.2 4.6 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ53120.1 - 6.6e-09 35.2 0.2 0.023 14.7 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ53120.1 - 1.4e-07 31.5 7.2 0.00027 21.0 0.8 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ53120.1 - 3.2e-07 30.8 2.6 0.018 15.5 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ53120.1 - 9e-07 29.1 1.8 0.27 12.0 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ53120.1 - 3.2e-06 26.6 0.0 6.9e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ53120.1 - 5.2e-06 26.5 0.1 4.4 7.9 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ53120.1 - 0.0003 21.0 4.5 0.37 11.1 0.0 3.7 3 1 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ53120.1 - 0.00065 19.9 4.4 0.13 12.5 0.1 3.4 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CDJ53120.1 - 0.0012 19.4 5.7 0.15 12.8 0.2 4.0 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ53120.1 - 0.0018 17.9 3.2 4.2 7.1 0.1 4.9 3 2 3 6 6 6 1 TPR repeat TPR_4 PF07721.14 CDJ53120.1 - 0.53 11.1 5.0 33 5.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat FAST_1 PF06743.15 CDJ53123.1 - 0.0075 16.2 3.7 2.7 8.0 0.0 5.2 5 2 2 7 7 7 2 FAST kinase-like protein, subdomain 1 SUIM_assoc PF16619.5 CDJ53123.1 - 7.8 6.7 21.4 0.26 11.4 0.6 4.5 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ53124.1 - 4.3 6.2 95.2 0.0059 15.6 8.4 6.7 5 1 1 6 6 6 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ53125.1 - 0.0055 16.8 31.6 0.095 12.7 0.4 2.7 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ53125.1 - 0.38 9.7 24.5 0.054 12.4 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ53125.1 - 0.71 9.4 33.8 0.13 11.8 4.7 2.6 3 0 0 3 3 3 0 Spt20 family FHIPEP PF00771.20 CDJ53125.1 - 1.1 7.6 8.9 3.2 6.1 7.2 1.9 2 0 0 2 2 2 0 FHIPEP family eIF-3_zeta PF05091.12 CDJ53125.1 - 4 6.3 10.3 7.5 5.4 6.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.17 CDJ53125.1 - 5.3 7.1 9.4 52 3.9 6.6 2.2 2 0 0 2 2 2 0 DDHD domain Neur_chan_memb PF02932.16 CDJ53125.1 - 7.5 6.5 6.2 25 4.8 3.4 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Lin-8 PF03353.15 CDJ53126.1 - 0.077 12.6 9.8 0.11 12.0 9.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ53126.1 - 0.14 12.1 32.6 0.22 11.5 32.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 CDJ53126.1 - 0.49 10.7 14.2 1.2 9.4 14.2 1.6 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein BRF1 PF07741.13 CDJ53126.1 - 0.86 10.0 9.0 0.15 12.5 1.1 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain CTU2 PF10288.9 CDJ53126.1 - 1 9.6 6.1 0.35 11.1 1.4 2.1 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 ANAPC_CDC26 PF10471.9 CDJ53126.1 - 1.7 9.5 32.6 0.55 11.1 17.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 GREB1 PF15782.5 CDJ53126.1 - 3 4.9 14.0 3.4 4.7 14.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RAB3GAP2_N PF14655.6 CDJ53126.1 - 3.5 6.8 11.6 0.12 11.6 5.5 1.5 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ETF_alpha PF00766.19 CDJ53126.1 - 3.9 7.6 11.0 0.097 12.7 2.5 2.1 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain DUF2681 PF10883.8 CDJ53126.1 - 5.1 7.6 16.6 0.33 11.4 5.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Cation_ATPase PF13246.6 CDJ53127.1 - 0.0083 16.2 0.1 0.0095 16.0 0.1 1.1 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Spt20 PF12090.8 CDJ53127.1 - 4.3 6.9 22.7 4.7 6.8 22.7 1.1 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ53127.1 - 5.4 5.9 27.4 5.1 6.0 27.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ53127.1 - 7.3 6.5 20.9 7.1 6.5 20.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ53128.1 - 0.0075 15.9 25.1 0.0075 15.9 25.1 3.2 1 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein TP53IP5 PF15331.6 CDJ53128.1 - 0.32 11.1 0.1 0.32 11.1 0.1 3.0 1 1 2 3 3 3 0 Cellular tumour antigen p53-inducible 5 eIF-3_zeta PF05091.12 CDJ53128.1 - 0.68 8.8 12.3 0.85 8.5 12.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spem1 PF15670.5 CDJ53128.1 - 0.75 9.3 9.2 5.5 6.5 8.4 2.3 2 0 0 2 2 2 0 Spermatid maturation protein 1 Connexin PF00029.19 CDJ53128.1 - 6 6.6 6.3 9.6 5.9 6.3 1.3 1 0 0 1 1 1 0 Connexin RskA PF10099.9 CDJ53129.1 - 0.003 17.9 0.4 0.0045 17.3 0.4 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ53130.1 - 5.1e-08 32.8 30.1 5.1e-08 32.8 30.1 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ53130.1 - 0.022 15.4 36.0 0.049 14.3 36.0 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Zip PF02535.22 CDJ53130.1 - 0.036 13.3 6.1 0.035 13.3 6.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Rubella_Capsid PF05750.11 CDJ53130.1 - 0.77 9.3 9.0 1.3 8.6 9.0 1.3 1 0 0 1 1 1 0 Rubella capsid protein Mem_trans PF03547.18 CDJ53130.1 - 1.2 7.4 2.0 1.2 7.5 2.0 1.2 1 0 0 1 1 1 0 Membrane transport protein Noggin PF05806.12 CDJ53130.1 - 5.3 6.9 15.1 3 7.7 2.2 2.2 2 0 0 2 2 2 0 Noggin Connexin PF00029.19 CDJ53130.1 - 9.3 5.9 16.9 0.14 11.9 7.6 2.0 2 0 0 2 2 2 0 Connexin DUF416 PF04222.12 CDJ53131.1 - 0.011 15.1 0.8 0.011 15.1 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF416) RecG_N PF17190.4 CDJ53131.1 - 2.9 8.7 6.3 53 4.6 2.8 3.0 2 0 0 2 2 2 0 RecG N-terminal helical domain Nucleoporin_FG PF13634.6 CDJ53132.1 - 9.4e-12 45.6 119.8 5.1e-07 30.5 27.8 14.1 11 4 2 13 13 13 5 Nucleoporin FG repeat region Nucleoporin2 PF04096.14 CDJ53132.1 - 1.4e-10 41.5 0.0 1.4e-10 41.5 0.0 3.7 4 1 0 4 4 4 1 Nucleoporin autopeptidase SR-25 PF10500.9 CDJ53132.1 - 0.0019 17.9 8.8 0.0019 17.9 8.8 9.2 9 2 0 10 10 10 2 Nuclear RNA-splicing-associated protein CcmF_C PF16327.5 CDJ53132.1 - 2.2 7.5 6.2 6.1 6.0 6.2 1.7 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal CitMHS PF03600.16 CDJ53134.1 - 2.3e-06 27.0 0.8 3.8e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Citrate transporter YfhO PF09586.10 CDJ53134.1 - 0.00026 19.4 1.3 0.00026 19.4 1.3 3.2 2 1 1 3 3 3 1 Bacterial membrane protein YfhO RRM_1 PF00076.22 CDJ53134.1 - 0.00044 20.0 0.0 0.00092 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AF-4 PF05110.13 CDJ53134.1 - 0.0016 16.6 33.1 0.0016 16.6 33.1 2.8 2 1 0 2 2 2 1 AF-4 proto-oncoprotein DUF5531 PF17671.1 CDJ53134.1 - 0.14 12.1 0.0 0.14 12.1 0.0 4.0 5 1 1 6 6 6 0 Family of unknown function (DUF5531) CytochromB561_N PF09786.9 CDJ53134.1 - 0.69 8.8 35.8 0.48 9.4 10.0 2.4 2 0 0 2 2 2 0 Cytochrome B561, N terminal SOG2 PF10428.9 CDJ53134.1 - 8.9 5.4 64.2 0.089 12.0 20.3 2.5 2 0 0 2 2 2 0 RAM signalling pathway protein Cupin_8 PF13621.6 CDJ53136.1 - 0.00086 19.1 1.1 0.0038 17.0 0.0 2.4 3 0 0 3 3 3 1 Cupin-like domain Spt20 PF12090.8 CDJ53136.1 - 0.0027 17.4 10.9 0.0027 17.4 10.9 2.2 2 0 0 2 2 2 1 Spt20 family EPL1 PF10513.9 CDJ53136.1 - 0.0031 17.9 8.8 0.3 11.5 1.3 2.1 2 0 0 2 2 2 2 Enhancer of polycomb-like DUF2722 PF10846.8 CDJ53136.1 - 0.0073 15.3 9.0 0.0073 15.3 9.0 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ53136.1 - 0.1 11.3 12.5 0.57 8.9 0.1 2.1 2 0 0 2 2 2 0 Presenilin Menin PF05053.13 CDJ53136.1 - 0.34 9.2 18.6 0.67 8.3 10.4 2.2 2 0 0 2 2 2 0 Menin Calici_coat_C PF08435.11 CDJ53136.1 - 0.36 10.3 4.3 5.6 6.4 0.6 2.3 2 0 0 2 2 2 0 Calicivirus coat protein C-terminal Neur_chan_memb PF02932.16 CDJ53136.1 - 0.46 10.5 8.9 2 8.4 0.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1360 PF07098.11 CDJ53136.1 - 1.6 8.7 6.7 1.3 9.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) DUF5527 PF17665.1 CDJ53136.1 - 1.7 8.2 4.7 4.7 6.8 1.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5527) SRP-alpha_N PF04086.13 CDJ53136.1 - 1.9 8.4 13.9 0.8 9.6 0.3 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Zip PF02535.22 CDJ53136.1 - 2 7.6 8.5 0.95 8.6 2.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter TCP PF03634.13 CDJ53136.1 - 2.5 8.6 18.5 1.9 9.0 0.3 2.3 2 0 0 2 2 2 0 TCP family transcription factor Apt1 PF10351.9 CDJ53136.1 - 4.2 6.1 22.7 0.99 8.2 15.8 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain RskA PF10099.9 CDJ53136.1 - 5.3 7.3 23.8 12 6.1 23.8 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA NPR3 PF03666.13 CDJ53136.1 - 8.2 5.1 15.4 0.72 8.6 5.9 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Peroxin-3 PF04882.12 CDJ53136.1 - 9.2 5.1 17.3 3.3 6.6 0.2 2.1 2 0 0 2 2 2 0 Peroxin-3 DUF572 PF04502.13 CDJ53137.1 - 0.27 10.8 26.8 0.4 10.2 26.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Spt20 PF12090.8 CDJ53138.1 - 4.3e-08 33.1 32.7 4.9e-06 26.3 17.5 2.3 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ53138.1 - 0.0052 15.8 1.3 0.0052 15.8 1.3 2.5 3 0 0 3 3 2 1 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ53138.1 - 0.017 16.1 5.3 0.017 16.1 5.3 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) EOS1 PF12326.8 CDJ53138.1 - 0.018 15.0 2.0 0.8 9.6 0.0 2.2 2 0 0 2 2 2 0 N-glycosylation protein MecA PF05389.12 CDJ53138.1 - 0.065 12.9 6.9 0.04 13.6 1.4 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Presenilin PF01080.17 CDJ53138.1 - 0.08 11.7 15.7 0.13 11.0 5.2 2.2 2 0 0 2 2 2 0 Presenilin Connexin PF00029.19 CDJ53138.1 - 0.16 11.7 7.4 0.21 11.3 1.6 2.1 2 0 0 2 2 2 0 Connexin GET2 PF08690.10 CDJ53138.1 - 0.33 10.6 19.8 0.34 10.6 8.3 2.8 3 0 0 3 3 3 0 GET complex subunit GET2 DUF3801 PF12687.7 CDJ53138.1 - 0.34 11.0 13.7 0.61 10.1 2.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3801) DUF913 PF06025.12 CDJ53138.1 - 0.4 9.6 6.4 1.1 8.1 1.7 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Endostatin PF06482.11 CDJ53138.1 - 0.48 9.8 11.7 0.72 9.3 3.7 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin ORC5_C PF14630.6 CDJ53138.1 - 0.51 9.8 5.8 0.48 9.9 0.9 2.2 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus TFIIA PF03153.13 CDJ53138.1 - 0.81 9.6 68.0 0.053 13.5 22.6 3.0 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit BRF1 PF07741.13 CDJ53138.1 - 1.3 9.4 15.4 2.6 8.4 7.0 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain BAF1_ABF1 PF04684.13 CDJ53138.1 - 1.5 7.8 19.8 0.022 13.8 1.5 2.7 3 0 0 3 3 2 0 BAF1 / ABF1 chromatin reorganising factor SLC12 PF03522.15 CDJ53138.1 - 1.7 7.6 10.3 1.2 8.1 4.3 2.1 2 0 0 2 2 2 0 Solute carrier family 12 EIIBC-GUT_N PF03612.14 CDJ53138.1 - 2.2 8.0 14.5 0.8 9.4 5.0 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Serinc PF03348.15 CDJ53138.1 - 2.6 6.9 7.6 3.2 6.6 1.6 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.12 CDJ53138.1 - 3.2 7.5 15.1 2.4 7.9 6.6 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ53138.1 - 3.3 6.6 25.4 1.3 7.9 13.6 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NPR1_interact PF15699.5 CDJ53138.1 - 3.8 8.2 14.2 16 6.2 8.5 2.4 2 0 0 2 2 2 0 NPR1 interacting HNOBA PF07701.14 CDJ53138.1 - 3.8 6.9 12.9 20 4.6 9.6 2.1 2 0 0 2 2 2 0 Heme NO binding associated DUF4471 PF14740.6 CDJ53138.1 - 4 6.6 9.6 1.9 7.6 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) AIF_C PF14721.6 CDJ53138.1 - 4.1 7.8 13.4 2.2 8.6 4.1 2.6 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Zip PF02535.22 CDJ53138.1 - 4.1 6.5 5.9 3.1 6.9 0.4 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter FmiP_Thoc5 PF09766.9 CDJ53138.1 - 4.6 6.4 21.2 5.1 6.3 10.3 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 TFB6 PF17110.5 CDJ53138.1 - 5.6 6.7 9.8 1.6 8.5 4.9 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH U1snRNP70_N PF12220.8 CDJ53138.1 - 6.2 7.5 15.2 13 6.5 0.4 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Roughex PF06020.11 CDJ53138.1 - 6.6 5.7 26.5 0.024 13.8 1.4 2.4 2 0 0 2 2 2 0 Drosophila roughex protein Peroxin-13_N PF04088.13 CDJ53138.1 - 6.8 7.0 11.4 4.1 7.7 4.0 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Suf PF05843.14 CDJ53138.1 - 9 6.2 28.5 0.78 9.7 4.5 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) ESM4 PF15952.5 CDJ53138.1 - 9.9 6.6 29.1 0.23 11.9 14.9 2.4 3 0 0 3 3 2 0 Enhancer of split M4 family Peptidase_S49_N PF08496.10 CDJ53138.1 - 10 6.2 15.1 0.94 9.5 3.6 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AF-4 PF05110.13 CDJ53140.1 - 0.079 11.0 48.7 0.088 10.9 48.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDK5_activator PF03261.15 CDJ53140.1 - 1.1 8.7 34.2 1.3 8.5 34.2 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CCSAP PF15748.5 CDJ53140.1 - 2 8.5 48.9 2.5 8.2 48.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PPP4R2 PF09184.11 CDJ53140.1 - 6.4 6.3 32.0 7.1 6.1 32.0 1.0 1 0 0 1 1 1 0 PPP4R2 Hamartin PF04388.12 CDJ53140.1 - 7.6 5.1 36.5 8.4 4.9 36.5 1.0 1 0 0 1 1 1 0 Hamartin protein RAP1 PF07218.11 CDJ53141.1 - 1.2 7.3 6.9 1.5 7.0 6.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mitofilin PF09731.9 CDJ53143.1 - 0.0027 16.6 8.9 0.0037 16.2 8.9 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RasGEF_N PF00618.20 CDJ53143.1 - 0.19 12.0 1.8 0.47 10.7 1.9 1.6 1 1 0 1 1 1 0 RasGEF N-terminal motif SWI-SNF_Ssr4 PF08549.10 CDJ53143.1 - 0.39 9.3 12.7 0.46 9.1 12.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SUIM_assoc PF16619.5 CDJ53143.1 - 1.4 9.0 33.5 0.17 11.9 7.6 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PAT1 PF09770.9 CDJ53143.1 - 3.6 5.8 13.9 3.7 5.7 13.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_1 PF00076.22 CDJ53146.1 - 2.4e-15 56.1 0.0 3.9e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDJ53146.1 - 0.063 13.3 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Mak16 PF04874.14 CDJ53147.1 - 3.5 8.3 9.1 2.7 8.7 1.3 2.6 2 0 0 2 2 2 0 Mak16 protein C-terminal region Presenilin PF01080.17 CDJ53147.1 - 3.6 6.3 19.7 0.26 10.0 14.8 1.7 2 0 0 2 2 2 0 Presenilin GCV_T_C PF08669.11 CDJ53149.1 - 1.8e-05 24.6 0.0 4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TFIIA PF03153.13 CDJ53149.1 - 6.2 6.7 45.3 6 6.7 7.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CorA PF01544.18 CDJ53149.1 - 9.6 5.4 16.5 15 4.8 16.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ribosomal_60s PF00428.19 CDJ53150.1 - 0.00059 20.4 11.2 0.00059 20.4 11.2 10.6 8 3 1 9 9 9 2 60s Acidic ribosomal protein NAM-associated PF14303.6 CDJ53150.1 - 0.0013 19.5 3.1 0.0013 19.5 3.1 5.5 2 1 1 4 4 4 1 No apical meristem-associated C-terminal domain CLN3 PF02487.17 CDJ53151.1 - 0.0091 15.1 0.8 0.0091 15.1 0.8 2.6 2 0 0 2 2 2 1 CLN3 protein Nop14 PF04147.12 CDJ53152.1 - 2.5 6.2 33.3 3.1 5.9 33.3 1.1 1 0 0 1 1 1 0 Nop14-like family SLC12 PF03522.15 CDJ53152.1 - 6.2 5.7 14.1 6.8 5.6 14.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF2151 PF10221.9 CDJ53152.1 - 6.6 5.2 12.7 7.3 5.1 12.7 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator LAP1C PF05609.12 CDJ53152.1 - 7.6 5.5 19.0 13 4.8 19.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 CDJ53152.1 - 8.8 5.0 20.8 10 4.8 20.8 1.2 1 0 0 1 1 1 0 Presenilin Red1 PF07964.11 CDJ53152.1 - 8.8 4.4 21.0 8.7 4.4 21.0 1.1 1 0 0 1 1 1 0 Rec10 / Red1 SAPS PF04499.15 CDJ53152.1 - 9.5 4.9 17.5 11 4.6 17.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Abhydrolase_9_N PF15420.6 CDJ53153.1 - 0.02 14.9 0.7 0.02 14.9 0.7 4.6 5 1 0 5 5 5 0 Alpha/beta-hydrolase family N-terminus Dpy19 PF10034.9 CDJ53153.1 - 2.9 6.0 5.6 15 3.6 0.6 3.4 4 0 0 4 4 4 0 Q-cell neuroblast polarisation Adaptin_N PF01602.20 CDJ53155.1 - 1.3e-54 185.7 0.0 4.2e-40 137.8 0.0 3.1 2 1 1 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 CDJ53155.1 - 1.2e-27 97.0 0.0 2.9e-27 95.7 0.0 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ53155.1 - 6.1e-06 26.5 2.7 0.0027 18.1 0.1 2.9 2 1 2 4 4 4 2 HEAT repeats HEAT PF02985.22 CDJ53155.1 - 8.3e-05 22.5 0.6 0.37 11.2 0.1 4.3 4 0 0 4 4 4 1 HEAT repeat OmpH PF03938.14 CDJ53155.1 - 0.0044 17.4 10.5 0.0096 16.3 10.5 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) API5 PF05918.11 CDJ53155.1 - 0.063 12.1 1.9 0.93 8.2 0.0 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) NAF PF03822.14 CDJ53155.1 - 0.2 11.8 0.1 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 NAF domain DUF2722 PF10846.8 CDJ53155.1 - 0.24 10.3 11.2 0.33 9.8 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) B2-adapt-app_C PF09066.10 CDJ53155.1 - 0.57 10.3 7.7 0.88 9.7 6.3 2.1 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain PhnG PF06754.12 CDJ53155.1 - 0.71 9.8 6.2 1.4 8.9 6.2 1.4 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG TFIIA PF03153.13 CDJ53155.1 - 0.84 9.6 12.5 1.2 9.0 12.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ53155.1 - 1.7 8.2 19.0 3 7.4 19.0 1.3 1 0 0 1 1 1 0 Spt20 family HEAT_EZ PF13513.6 CDJ53155.1 - 7.9 7.1 10.9 0.69 10.5 0.3 4.2 5 1 0 5 5 4 0 HEAT-like repeat Androgen_recep PF02166.16 CDJ53155.1 - 8.2 5.1 15.7 12 4.6 15.7 1.1 1 0 0 1 1 1 0 Androgen receptor DUF2722 PF10846.8 CDJ53156.1 - 1.1e-05 24.7 39.0 0.0002 20.5 3.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ53156.1 - 2.2e-05 24.2 53.9 8.2e-05 22.3 6.4 2.2 2 0 0 2 2 2 1 Spt20 family DUF4667 PF15700.5 CDJ53156.1 - 0.00016 21.8 15.1 0.0012 19.0 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) Med15 PF09606.10 CDJ53156.1 - 0.00054 18.8 43.3 0.025 13.3 10.2 2.5 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Glt_symporter PF03616.14 CDJ53156.1 - 0.0006 18.6 7.7 0.001 17.8 1.0 2.3 2 0 0 2 2 2 1 Sodium/glutamate symporter Band_3_cyto PF07565.13 CDJ53156.1 - 0.00093 19.1 8.7 0.029 14.2 2.9 2.2 2 0 0 2 2 2 2 Band 3 cytoplasmic domain Eapp_C PF10238.9 CDJ53156.1 - 0.001 19.2 15.4 0.049 13.7 7.2 2.4 2 0 0 2 2 2 2 E2F-associated phosphoprotein FmiP_Thoc5 PF09766.9 CDJ53156.1 - 0.0023 17.3 6.6 0.0023 17.3 6.6 2.1 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 CobT PF06213.12 CDJ53156.1 - 0.0023 17.4 11.0 0.0023 17.4 11.0 3.0 3 0 0 3 3 2 1 Cobalamin biosynthesis protein CobT SpoIIP PF07454.11 CDJ53156.1 - 0.0023 17.4 17.7 0.031 13.7 8.5 2.1 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) BRF1 PF07741.13 CDJ53156.1 - 0.0028 18.0 18.0 0.056 13.8 2.2 2.6 2 0 0 2 2 2 2 Brf1-like TBP-binding domain eIF-3_zeta PF05091.12 CDJ53156.1 - 0.0031 16.5 20.6 0.14 11.1 1.7 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S15 PF02129.18 CDJ53156.1 - 0.0032 17.1 24.3 0.11 12.0 10.5 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DUF702 PF05142.12 CDJ53156.1 - 0.0034 17.9 12.5 0.061 13.8 4.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF702) PNISR PF15996.5 CDJ53156.1 - 0.0038 17.5 6.1 0.0038 17.5 6.1 2.8 3 0 0 3 3 2 1 Arginine/serine-rich protein PNISR EPL1 PF10513.9 CDJ53156.1 - 0.0045 17.4 19.5 0.061 13.7 0.5 2.5 3 0 0 3 3 2 2 Enhancer of polycomb-like Apc15p PF05841.11 CDJ53156.1 - 0.0056 17.5 28.7 0.0059 17.4 2.5 3.3 3 0 0 3 3 3 2 Apc15p protein Afi1 PF07792.12 CDJ53156.1 - 0.0061 17.0 15.7 0.23 12.0 7.0 2.3 2 0 0 2 2 2 2 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2052 PF09747.9 CDJ53156.1 - 0.0073 16.5 19.3 0.26 11.4 8.7 2.2 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) PA26 PF04636.13 CDJ53156.1 - 0.0088 15.0 10.6 0.051 12.5 1.9 2.1 2 0 0 2 2 2 2 PA26 p53-induced protein (sestrin) MMR1 PF08505.10 CDJ53156.1 - 0.016 15.5 7.6 0.016 15.5 7.6 2.5 2 1 0 2 2 1 0 Mitochondrial Myo2 receptor-related protein DUF4770 PF15994.5 CDJ53156.1 - 0.016 15.4 19.4 0.11 12.7 8.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) MDM10 PF12519.8 CDJ53156.1 - 0.024 13.5 13.7 0.035 13.0 13.7 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF3807 PF12720.7 CDJ53156.1 - 0.03 14.6 26.0 0.048 13.9 9.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Consortin_C PF15281.6 CDJ53156.1 - 0.031 14.3 1.5 0.031 14.3 1.5 2.3 2 0 0 2 2 2 0 Consortin C-terminus DUF4746 PF15928.5 CDJ53156.1 - 0.033 13.6 13.5 0.54 9.6 6.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) HA2 PF04408.23 CDJ53156.1 - 0.034 14.4 12.8 0.45 10.8 3.0 2.7 2 0 0 2 2 2 0 Helicase associated domain (HA2) LIM_bind PF01803.16 CDJ53156.1 - 0.04 13.4 13.6 0.38 10.2 5.4 2.3 2 0 0 2 2 2 0 LIM-domain binding protein DUF4175 PF13779.6 CDJ53156.1 - 0.057 11.3 42.2 0.006 14.6 19.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) RXT2_N PF08595.11 CDJ53156.1 - 0.086 12.9 12.2 0.38 10.8 3.8 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Rxt3 PF08642.10 CDJ53156.1 - 0.11 13.3 10.5 2.4 8.9 4.0 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 EIIBC-GUT_N PF03612.14 CDJ53156.1 - 0.12 12.1 22.3 0.035 13.8 7.3 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Peroxin-3 PF04882.12 CDJ53156.1 - 0.12 11.3 19.0 0.47 9.4 2.9 2.3 2 1 0 2 2 2 0 Peroxin-3 Slu7 PF11708.8 CDJ53156.1 - 0.13 12.0 19.3 0.85 9.3 10.0 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor RR_TM4-6 PF06459.12 CDJ53156.1 - 0.14 12.0 20.6 0.093 12.5 6.4 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 CDJ53156.1 - 0.16 12.2 29.7 0.063 13.4 6.2 3.2 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated DUF4820 PF16091.5 CDJ53156.1 - 0.16 11.3 15.4 0.044 13.1 4.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) FAM91_C PF14648.6 CDJ53156.1 - 0.16 10.8 9.8 0.073 11.9 3.1 2.0 2 0 0 2 2 2 0 FAM91 C-terminus DUF2784 PF10861.8 CDJ53156.1 - 0.16 12.0 0.1 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of Unknown function (DUF2784) DUF1644 PF07800.12 CDJ53156.1 - 0.17 11.9 10.4 1.2 9.2 5.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) HNOBA PF07701.14 CDJ53156.1 - 0.17 11.3 14.4 1.5 8.2 0.2 2.1 2 0 0 2 2 2 0 Heme NO binding associated EFTUD2 PF16004.5 CDJ53156.1 - 0.2 12.2 22.0 0.067 13.8 7.5 2.6 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus CPSF100_C PF13299.6 CDJ53156.1 - 0.2 11.8 18.0 0.11 12.7 5.2 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3043 PF11241.8 CDJ53156.1 - 0.24 11.4 14.3 0.1 12.6 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF4647 PF15504.6 CDJ53156.1 - 0.27 10.3 21.4 0.09 11.9 6.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) SART-1 PF03343.13 CDJ53156.1 - 0.32 9.5 26.6 1 7.8 9.8 2.1 2 0 0 2 2 2 0 SART-1 family TRAP_alpha PF03896.16 CDJ53156.1 - 0.33 10.1 12.7 0.28 10.4 1.9 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit RLL PF10036.9 CDJ53156.1 - 0.33 10.8 21.8 0.15 11.9 0.6 2.3 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein DUF3801 PF12687.7 CDJ53156.1 - 0.41 10.7 18.6 0.94 9.5 7.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) EOS1 PF12326.8 CDJ53156.1 - 0.46 10.4 8.5 2.5 8.0 2.7 2.3 2 0 0 2 2 2 0 N-glycosylation protein Peptidase_S49_N PF08496.10 CDJ53156.1 - 0.51 10.4 20.0 1.7 8.7 3.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1764 PF08576.10 CDJ53156.1 - 0.58 11.1 19.1 1.6 9.7 7.8 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) CNDH2_C PF16858.5 CDJ53156.1 - 0.58 10.0 21.3 0.94 9.3 10.6 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term PAT1 PF09770.9 CDJ53156.1 - 0.6 8.3 33.8 0.47 8.7 17.2 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RPA43_OB PF17875.1 CDJ53156.1 - 0.6 10.7 15.5 1.1 9.9 5.2 2.8 3 0 0 3 3 2 0 RPA43 OB domain in RNA Pol I CFIA_Pcf11 PF11526.8 CDJ53156.1 - 0.61 10.6 21.7 0.55 10.7 7.2 3.2 3 0 0 3 3 2 0 Subunit of cleavage factor IA Pcf11 DUF5523 PF17661.1 CDJ53156.1 - 0.68 9.6 24.4 0.14 11.8 10.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) YABBY PF04690.13 CDJ53156.1 - 0.7 10.5 16.1 1.1 9.8 4.6 2.3 2 0 0 2 2 2 0 YABBY protein DUF4518 PF15008.6 CDJ53156.1 - 0.78 8.9 17.8 0.83 8.8 8.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) TCP PF03634.13 CDJ53156.1 - 0.78 10.3 29.1 0.71 10.4 8.5 3.2 3 0 0 3 3 3 0 TCP family transcription factor V_ATPase_I PF01496.19 CDJ53156.1 - 0.85 7.5 20.8 0.061 11.2 8.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family OATP PF03137.20 CDJ53156.1 - 0.88 7.8 8.8 0.17 10.2 1.6 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Myc_N PF01056.18 CDJ53156.1 - 0.94 9.3 13.5 0.047 13.6 2.0 2.9 3 0 0 3 3 3 0 Myc amino-terminal region PRC2_HTH_1 PF18118.1 CDJ53156.1 - 1.1 10.1 16.5 3.9 8.3 0.2 2.5 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain MAS20 PF02064.15 CDJ53156.1 - 1.1 9.3 29.8 1.8 8.7 17.1 2.6 2 0 0 2 2 2 0 MAS20 protein import receptor ATP11 PF06644.11 CDJ53156.1 - 1.4 8.7 22.2 0.45 10.3 7.9 2.3 2 0 0 2 2 2 0 ATP11 protein FHIPEP PF00771.20 CDJ53156.1 - 1.6 7.1 14.8 0.33 9.4 4.1 2.1 2 0 0 2 2 2 0 FHIPEP family NEMP PF10225.9 CDJ53156.1 - 1.6 8.3 7.8 3.9 7.1 1.2 2.3 2 0 0 2 2 2 0 NEMP family CTU2 PF10288.9 CDJ53156.1 - 1.9 8.7 19.9 0.59 10.4 6.4 2.7 3 0 0 3 3 2 0 Cytoplasmic tRNA 2-thiolation protein 2 XAP5 PF04921.14 CDJ53156.1 - 2.1 8.1 14.3 1.1 9.0 4.0 2.2 2 0 0 2 2 2 0 XAP5, circadian clock regulator AUX_IAA PF02309.16 CDJ53156.1 - 2.1 8.1 11.6 0.49 10.2 7.6 1.9 2 1 0 2 2 1 0 AUX/IAA family DUF5327 PF17261.2 CDJ53156.1 - 2.2 9.1 35.9 1.6 9.6 16.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) CagX PF03524.15 CDJ53156.1 - 2.3 7.9 14.6 2.6 7.7 1.4 2.4 2 0 0 2 2 2 0 Conjugal transfer protein Pannexin_like PF12534.8 CDJ53156.1 - 2.5 7.1 14.0 0.35 9.9 3.6 2.3 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Cyclin_C PF02984.19 CDJ53156.1 - 2.7 8.1 16.2 0.79 9.8 2.8 2.9 2 0 0 2 2 2 0 Cyclin, C-terminal domain ALMT PF11744.8 CDJ53156.1 - 3 6.6 15.4 1 8.1 5.1 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Het-C PF07217.11 CDJ53156.1 - 3.2 6.2 13.4 0.11 11.0 2.2 2.0 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C Lin-8 PF03353.15 CDJ53156.1 - 3.3 7.2 30.5 2.8 7.4 10.6 2.4 2 1 0 2 2 2 0 Ras-mediated vulval-induction antagonist dsRBD2 PF17842.1 CDJ53156.1 - 3.3 7.9 12.7 0.6 10.3 3.2 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 Sec62 PF03839.16 CDJ53156.1 - 3.4 7.1 15.8 5.4 6.4 1.2 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 Orf78 PF06024.12 CDJ53156.1 - 3.6 7.9 15.3 1.1 9.6 5.6 2.4 2 0 0 2 2 2 0 Orf78 (ac78) TFIIA PF03153.13 CDJ53156.1 - 3.7 7.4 67.4 0.052 13.5 31.8 2.3 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pal1 PF08316.11 CDJ53156.1 - 3.7 8.3 10.7 1.7 9.4 1.4 2.5 2 0 0 2 2 2 0 Pal1 cell morphology protein DUF2464 PF10240.9 CDJ53156.1 - 4 6.9 10.7 3.2 7.2 3.8 2.2 2 0 0 2 2 2 0 Multivesicular body subunit 12 Ferlin_C PF16165.5 CDJ53156.1 - 4.1 7.3 9.9 1.7 8.6 1.1 2.2 2 0 0 2 2 2 0 Ferlin C-terminus FAM176 PF14851.6 CDJ53156.1 - 4.1 7.1 17.6 0.88 9.2 7.6 2.3 2 0 0 2 2 2 0 FAM176 family SAE2 PF08573.10 CDJ53156.1 - 4.5 8.4 19.2 9.5 7.4 7.0 2.5 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Tim54 PF11711.8 CDJ53156.1 - 4.5 5.9 24.3 2.6 6.7 12.8 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF1115 PF06544.12 CDJ53156.1 - 5.1 7.2 15.3 0.63 10.1 4.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) DUF775 PF05603.12 CDJ53156.1 - 5.6 6.4 23.7 5.3 6.5 10.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF775) FAM222A PF15258.6 CDJ53156.1 - 6 5.9 32.1 3.7 6.6 6.8 2.6 2 0 0 2 2 2 0 Protein family of FAM222A Jak1_Phl PF17887.1 CDJ53156.1 - 6 6.8 21.8 0.46 10.4 1.5 2.3 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain DUF1980 PF09323.10 CDJ53156.1 - 7.3 6.5 18.1 0.68 9.8 6.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CNDH2_M PF16869.5 CDJ53156.1 - 7.4 7.3 22.0 3.2 8.4 0.8 3.4 3 0 0 3 3 3 0 PF16858 PSK PF06404.12 CDJ53156.1 - 8.1 7.5 22.6 1.2 10.1 8.5 2.9 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) Med19 PF10278.9 CDJ53156.1 - 8.1 6.3 13.1 9.3 6.1 5.6 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Paramyxo_ncap PF00973.19 CDJ53156.1 - 8.4 5.2 18.7 0.2 10.6 6.1 2.1 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein Baculo_PP31 PF05311.11 CDJ53156.1 - 8.5 5.8 20.2 1.6 8.2 0.6 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) ANAPC1 PF12859.7 CDJ53156.1 - 8.9 6.9 15.1 0.38 11.3 2.5 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 1 VIR_N PF15912.5 CDJ53156.1 - 9.3 5.8 11.6 0.66 9.5 1.5 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal Hydin_ADK PF17213.3 CDJ53156.1 - 9.6 6.4 24.0 1.1 9.5 3.0 2.9 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain Peroxin-13_N PF04088.13 CDJ53156.1 - 9.7 6.5 14.5 4 7.7 5.1 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region RuvC_III PF18541.1 CDJ53156.1 - 9.8 6.1 19.7 7.3 6.5 3.4 2.1 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 Saw1 PF11561.8 CDJ53157.1 - 0.54 9.8 3.3 0.34 10.4 0.7 1.9 2 0 0 2 2 2 0 Single strand annealing-weakened 1 DUF4820 PF16091.5 CDJ53157.1 - 0.57 9.5 7.5 0.76 9.1 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) PA26 PF04636.13 CDJ53157.1 - 3.5 6.4 11.9 0.66 8.8 3.9 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) AAA_23 PF13476.6 CDJ53157.1 - 8.8 6.8 24.1 10 6.6 10.0 3.1 3 0 0 3 3 3 0 AAA domain DUF572 PF04502.13 CDJ53158.1 - 0.1 12.2 24.1 0.15 11.7 24.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2207 PF09972.9 CDJ53158.1 - 1.6 7.4 4.5 2.2 7.0 4.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) V_ATPase_I PF01496.19 CDJ53158.1 - 6 4.7 32.7 2.7 5.8 4.8 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2052 PF09747.9 CDJ53158.1 - 7.8 6.6 39.6 5.3 7.1 25.7 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Peptidase_M1 PF01433.20 CDJ53160.1 - 1.9e-41 142.0 0.0 3.3e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 CDJ53160.1 - 2.6e-15 56.7 0.1 2.6e-15 56.7 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 CDJ53160.1 - 2e-09 37.9 0.0 4.7e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF3458_C PF17432.2 CDJ53160.1 - 2.9e-07 30.2 0.1 6.4e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats SUIM_assoc PF16619.5 CDJ53160.1 - 1.7e-05 24.8 13.7 0.016 15.2 0.0 3.6 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 Peptidase_M61 PF05299.12 CDJ53160.1 - 0.025 15.0 1.7 0.025 15.0 1.7 3.6 3 1 0 3 3 3 0 M61 glycyl aminopeptidase DUF3446 PF11928.8 CDJ53160.1 - 0.069 13.5 1.3 0.2 12.0 1.3 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain DNA_pol_phi PF04931.13 CDJ53161.1 - 0.72 7.9 1.5 0.88 7.6 1.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CDJ53163.1 - 0.55 8.5 19.1 0.63 8.3 19.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ53163.1 - 0.88 8.5 26.3 0.96 8.4 26.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ53163.1 - 1.4 8.7 23.3 1.6 8.5 23.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mgr1 PF08602.10 CDJ53163.1 - 2.1 7.1 14.8 2.6 6.8 14.8 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit HSP70 PF00012.20 CDJ53163.1 - 6 4.9 17.8 6.1 4.9 17.8 1.1 1 0 0 1 1 1 0 Hsp70 protein Membralin PF09746.9 CDJ53163.1 - 6.1 5.8 16.3 7.3 5.5 16.3 1.3 1 0 0 1 1 1 0 Tumour-associated protein TMPIT PF07851.13 CDJ53163.1 - 7.2 5.7 24.2 8.2 5.6 24.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein ALMT PF11744.8 CDJ53163.1 - 8.2 5.1 23.9 8.9 5.0 23.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SID-1_RNA_chan PF13965.6 CDJ53163.1 - 8.6 4.6 9.9 9.7 4.5 9.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LAP1C PF05609.12 CDJ53163.1 - 8.6 5.3 27.6 11 5.0 27.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Glyco_transf_17 PF04724.13 CDJ53165.1 - 3.3e-18 65.9 0.3 1.2e-17 64.0 0.3 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 17 LPD16 PF18830.1 CDJ53165.1 - 0.037 14.0 0.1 2.5 8.1 0.0 2.8 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 16 CCDC53 PF10152.9 CDJ53165.1 - 0.29 11.5 7.0 0.53 10.7 2.8 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 CDJ53165.1 - 2.8 6.6 4.5 4.9 5.8 4.5 1.3 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ53166.1 - 0.0056 16.3 17.2 0.0065 16.1 17.2 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ53166.1 - 0.01 15.8 14.9 0.012 15.6 14.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rbc25 PF08292.12 CDJ53166.1 - 0.29 11.4 3.9 0.46 10.7 3.9 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Macoilin PF09726.9 CDJ53166.1 - 1.1 7.8 22.1 1.3 7.5 22.1 1.1 1 0 0 1 1 1 0 Macoilin family MPM1 PF17234.2 CDJ53166.1 - 2.4 8.4 12.5 5.4 7.3 12.5 1.7 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Presenilin PF01080.17 CDJ53166.1 - 9.9 4.8 9.3 10 4.8 9.3 1.2 1 0 0 1 1 1 0 Presenilin Ku_PK_bind PF08785.11 CDJ53168.1 - 3.3e-08 33.7 12.6 2.8e-05 24.3 0.8 4.4 2 1 0 3 3 2 2 Ku C terminal domain like DUF2722 PF10846.8 CDJ53168.1 - 0.00019 20.5 4.4 0.00019 20.5 4.4 10.1 5 3 4 10 10 2 2 Protein of unknown function (DUF2722) DUF4604 PF15377.6 CDJ53168.1 - 0.00053 20.4 11.4 0.00053 20.4 11.4 5.7 3 1 1 4 4 2 1 Domain of unknown function (DUF4604) SLC12 PF03522.15 CDJ53168.1 - 0.0014 17.7 16.6 0.0014 17.7 16.6 5.0 4 1 0 4 4 3 2 Solute carrier family 12 MAP17 PF15807.5 CDJ53168.1 - 0.0014 18.8 10.3 0.0014 18.8 10.3 8.0 7 1 0 7 7 6 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TRAP_alpha PF03896.16 CDJ53168.1 - 0.0051 16.1 7.8 0.0051 16.1 7.8 6.4 5 2 0 6 6 5 1 Translocon-associated protein (TRAP), alpha subunit Connexin PF00029.19 CDJ53168.1 - 0.0057 16.5 9.9 0.0057 16.5 9.9 7.2 7 1 0 7 7 6 2 Connexin FAM176 PF14851.6 CDJ53168.1 - 0.0063 16.2 7.3 0.0063 16.2 7.3 7.5 5 2 2 7 7 6 2 FAM176 family SpoIIIAH PF12685.7 CDJ53168.1 - 0.0076 16.1 18.9 0.0076 16.1 18.9 5.9 2 1 2 4 4 2 1 SpoIIIAH-like protein DUF3169 PF11368.8 CDJ53168.1 - 0.021 14.3 0.5 0.021 14.3 0.5 4.6 6 0 0 6 6 5 0 Protein of unknown function (DUF3169) Oxidored_q3 PF00499.20 CDJ53168.1 - 0.4 10.4 3.2 1.8 8.3 0.4 3.5 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF1772 PF08592.11 CDJ53168.1 - 3.1 8.1 0.0 3.1 8.1 0.0 6.0 4 2 1 5 5 3 0 Domain of unknown function (DUF1772) MRP-S31 PF15433.6 CDJ53171.1 - 0.3 10.7 43.6 0.46 10.1 43.6 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF4834 PF16118.5 CDJ53172.1 - 3.2e-08 34.4 11.1 4.9e-08 33.8 11.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Tmemb_9 PF05434.11 CDJ53172.1 - 4.7e-05 23.3 11.5 5.8e-05 23.0 11.5 1.2 1 0 0 1 1 1 1 TMEM9 CBP_BcsG PF11658.8 CDJ53172.1 - 0.0001 20.9 11.9 0.0001 20.9 11.9 1.0 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG FHIPEP PF00771.20 CDJ53172.1 - 0.00015 20.4 8.1 0.00016 20.3 8.1 1.0 1 0 0 1 1 1 1 FHIPEP family SID-1_RNA_chan PF13965.6 CDJ53172.1 - 0.00017 20.2 5.3 0.00017 20.2 5.3 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 CDJ53172.1 - 0.00029 18.9 14.5 0.00033 18.8 14.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4131 PF13567.6 CDJ53172.1 - 0.00042 20.0 1.0 0.00052 19.7 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) PepSY_TM PF03929.16 CDJ53172.1 - 0.00045 20.0 5.0 0.00045 20.0 5.0 1.7 1 1 1 2 2 1 1 PepSY-associated TM region OATP PF03137.20 CDJ53172.1 - 0.00049 18.5 2.9 0.00057 18.3 2.9 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_3_6 PF07332.11 CDJ53172.1 - 0.00049 20.1 1.5 0.00056 19.9 1.5 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_S49_N PF08496.10 CDJ53172.1 - 0.00053 20.1 12.7 0.00058 19.9 12.7 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Connexin PF00029.19 CDJ53172.1 - 0.00056 19.7 6.6 0.00071 19.4 6.6 1.3 1 0 0 1 1 1 1 Connexin TMEM208_SND2 PF05620.11 CDJ53172.1 - 0.00077 19.3 6.9 0.0011 18.8 6.9 1.3 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF808 PF05661.12 CDJ53172.1 - 0.00099 18.2 3.4 0.0012 18.0 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF808) Pex24p PF06398.11 CDJ53172.1 - 0.0011 18.0 1.6 0.0013 17.8 1.6 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin SARAF PF06682.12 CDJ53172.1 - 0.0015 18.3 3.4 0.0021 17.8 3.4 1.3 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CLN3 PF02487.17 CDJ53172.1 - 0.0018 17.4 7.7 0.0021 17.2 7.7 1.1 1 0 0 1 1 1 1 CLN3 protein DUF2244 PF10003.9 CDJ53172.1 - 0.002 17.8 0.4 0.0021 17.7 0.4 1.0 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) Wzy_C PF04932.15 CDJ53172.1 - 0.0021 17.7 0.2 0.0025 17.5 0.2 1.1 1 0 0 1 1 1 1 O-Antigen ligase YfhO PF09586.10 CDJ53172.1 - 0.0021 16.4 13.4 0.0022 16.3 13.4 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO CitMHS PF03600.16 CDJ53172.1 - 0.0036 16.6 1.8 0.0036 16.5 1.8 1.1 1 0 0 1 1 1 1 Citrate transporter Folate_carrier PF01770.18 CDJ53172.1 - 0.0038 16.0 7.9 0.0039 16.0 7.9 1.0 1 0 0 1 1 1 1 Reduced folate carrier DUF929 PF06053.11 CDJ53172.1 - 0.0049 16.2 5.4 0.007 15.7 5.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF929) Choline_transpo PF04515.12 CDJ53172.1 - 0.0052 16.0 0.4 0.0059 15.9 0.4 1.2 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF4010 PF13194.6 CDJ53172.1 - 0.0053 16.5 2.8 0.0057 16.4 2.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) DcuA_DcuB PF03605.14 CDJ53172.1 - 0.0089 15.0 6.3 0.0098 14.8 6.3 1.1 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter O-antigen_lig PF13425.6 CDJ53172.1 - 0.0091 14.8 8.8 0.01 14.7 8.8 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein FPN1 PF06963.12 CDJ53172.1 - 0.0092 14.6 5.9 0.0098 14.5 5.9 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) LRR19-TM PF15176.6 CDJ53172.1 - 0.01 15.8 1.1 0.013 15.5 1.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF2852 PF11014.8 CDJ53172.1 - 0.011 15.9 3.3 0.012 15.7 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF3487 PF11990.8 CDJ53172.1 - 0.014 15.2 3.5 0.016 15.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) CSG2 PF16965.5 CDJ53172.1 - 0.017 14.1 4.9 0.02 13.9 4.9 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator 7tm_1 PF00001.21 CDJ53172.1 - 0.017 14.4 5.2 0.021 14.2 5.2 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF5313 PF17240.2 CDJ53172.1 - 0.017 15.5 7.3 0.02 15.3 7.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5313) MARVEL PF01284.23 CDJ53172.1 - 0.02 14.9 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 Membrane-associating domain PRA1 PF03208.19 CDJ53172.1 - 0.022 14.4 1.6 0.025 14.2 1.6 1.2 1 0 0 1 1 1 0 PRA1 family protein DUF4770 PF15994.5 CDJ53172.1 - 0.025 14.8 10.0 0.027 14.7 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) HemX PF04375.14 CDJ53172.1 - 0.025 13.9 24.9 0.027 13.7 24.9 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Trp_oprn_chp PF09534.10 CDJ53172.1 - 0.031 14.1 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PIG-P PF08510.12 CDJ53172.1 - 0.034 14.1 0.6 0.048 13.6 0.6 1.4 1 0 0 1 1 1 0 PIG-P Nucleoside_tran PF01733.18 CDJ53172.1 - 0.042 13.2 4.1 0.047 13.1 4.1 1.1 1 0 0 1 1 1 0 Nucleoside transporter NS3_envE PF02723.14 CDJ53172.1 - 0.047 13.8 10.6 0.055 13.6 10.6 1.1 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E SpoIIP PF07454.11 CDJ53172.1 - 0.058 12.8 10.1 0.058 12.8 10.1 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) HA2 PF04408.23 CDJ53172.1 - 0.069 13.4 2.8 0.077 13.3 2.8 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) AIF_C PF14721.6 CDJ53172.1 - 0.086 13.2 5.8 0.09 13.1 5.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CobT PF06213.12 CDJ53172.1 - 0.09 12.2 14.1 0.094 12.1 14.1 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MFS_1_like PF12832.7 CDJ53172.1 - 0.093 11.6 1.7 0.11 11.3 1.7 1.3 1 0 0 1 1 1 0 MFS_1 like family CPSF100_C PF13299.6 CDJ53172.1 - 0.098 12.8 7.8 0.1 12.7 7.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 CDJ53172.1 - 0.099 12.8 7.4 0.1 12.8 7.4 1.0 1 0 0 1 1 1 0 DDHD domain ArAE_2_N PF10337.9 CDJ53172.1 - 0.11 11.5 18.3 0.11 11.5 18.3 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal EIIBC-GUT_N PF03612.14 CDJ53172.1 - 0.11 12.2 9.3 0.11 12.2 9.3 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus NEMP PF10225.9 CDJ53172.1 - 0.11 12.1 8.0 0.13 11.9 8.0 1.2 1 0 0 1 1 1 0 NEMP family CobD_Cbib PF03186.13 CDJ53172.1 - 0.12 11.6 1.6 0.12 11.5 1.6 1.1 1 0 0 1 1 1 0 CobD/Cbib protein RHD3 PF05879.12 CDJ53172.1 - 0.12 10.5 10.7 0.12 10.5 10.7 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) FxsA PF04186.13 CDJ53172.1 - 0.19 11.8 14.9 0.27 11.4 14.9 1.3 1 1 0 1 1 1 0 FxsA cytoplasmic membrane protein POPLD PF08170.12 CDJ53172.1 - 0.21 12.0 6.0 0.26 11.6 6.0 1.2 1 0 0 1 1 1 0 POPLD (NUC188) domain R_equi_Vir PF05526.11 CDJ53172.1 - 0.22 11.4 3.8 0.25 11.2 3.8 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Pannexin_like PF12534.8 CDJ53172.1 - 0.22 10.6 14.3 0.26 10.4 14.3 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Herpes_LMP1 PF05297.11 CDJ53172.1 - 0.26 10.4 2.3 0.24 10.6 2.3 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) YABBY PF04690.13 CDJ53172.1 - 0.34 11.5 8.7 0.37 11.3 8.7 1.1 1 0 0 1 1 1 0 YABBY protein Mem_trans PF03547.18 CDJ53172.1 - 0.39 9.1 12.9 0.44 8.9 12.9 1.0 1 0 0 1 1 1 0 Membrane transport protein EMC3_TMCO1 PF01956.16 CDJ53172.1 - 0.41 10.3 18.1 0.52 10.0 18.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PepSY_TM_like_2 PF16357.5 CDJ53172.1 - 0.42 10.6 11.2 0.21 11.5 9.4 1.5 1 1 0 1 1 1 0 Putative PepSY_TM-like DUF3402 PF11882.8 CDJ53172.1 - 0.61 9.1 17.2 0.68 9.0 17.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) 7tm_7 PF08395.12 CDJ53172.1 - 0.69 9.1 17.8 0.98 8.6 17.8 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor Ac76 PF05814.11 CDJ53172.1 - 1.3 9.1 19.0 3.4 7.8 19.0 1.7 1 1 0 1 1 1 0 Orf76 (Ac76) FAM176 PF14851.6 CDJ53172.1 - 1.6 8.4 14.5 3.4 7.3 14.5 1.6 1 1 0 1 1 1 0 FAM176 family Comm PF15957.5 CDJ53172.1 - 1.7 9.0 12.5 3.1 8.2 12.5 1.5 1 1 0 1 1 1 0 Commissureless TRAP_alpha PF03896.16 CDJ53172.1 - 2.3 7.4 12.9 4 6.5 12.9 1.5 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit tRNA_anti-like PF12869.7 CDJ53172.1 - 2.4 7.7 15.2 4.7 6.8 15.2 1.5 1 1 0 1 1 1 0 tRNA_anti-like TMEM51 PF15345.6 CDJ53172.1 - 2.5 7.9 22.0 0.89 9.3 19.9 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 Folliculin PF11704.8 CDJ53172.1 - 3 7.7 10.8 3.3 7.6 10.8 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport SCIMP PF15050.6 CDJ53172.1 - 3.5 8.1 10.5 5.5 7.5 10.5 1.4 1 1 0 1 1 1 0 SCIMP protein Coilin_N PF15862.5 CDJ53172.1 - 3.8 7.3 15.8 4.7 7.0 15.8 1.2 1 0 0 1 1 1 0 Coilin N-terminus Neur_chan_memb PF02932.16 CDJ53172.1 - 4.2 7.4 17.0 8 6.4 17.0 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3742 PF12553.8 CDJ53172.1 - 4.3 7.5 6.4 9.2 6.4 6.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3742) RskA PF10099.9 CDJ53172.1 - 4.4 7.6 13.5 7.9 6.7 13.5 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF898 PF05987.13 CDJ53172.1 - 4.5 6.2 9.6 8 5.4 9.6 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) eIF-3_zeta PF05091.12 CDJ53172.1 - 4.8 6.0 18.7 5.1 6.0 18.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Asparaginase_2 PF01112.18 CDJ53172.1 - 7.4 5.5 11.0 8.1 5.4 11.0 1.0 1 0 0 1 1 1 0 Asparaginase DUF2393 PF09624.10 CDJ53172.1 - 7.7 6.5 11.9 5.7 6.9 10.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2393) COPI_assoc PF08507.10 CDJ53172.1 - 7.8 6.6 13.2 14 5.8 13.2 1.5 1 1 0 1 1 1 0 COPI associated protein SseC PF04888.12 CDJ53172.1 - 8.7 5.8 26.3 10 5.6 26.3 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF2232 PF09991.9 CDJ53172.1 - 8.7 5.4 22.1 2.9 7.0 19.9 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4446 PF14584.6 CDJ53172.1 - 9.6 6.2 20.8 15 5.6 20.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Tubulin PF00091.25 CDJ53173.1 - 6.9e-67 225.5 0.0 9.6e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ53173.1 - 6e-51 171.9 0.3 1.6e-50 170.5 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDJ53173.1 - 0.039 13.6 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Tubulin domain Macoilin PF09726.9 CDJ53174.1 - 0.21 10.1 38.1 0.28 9.7 38.1 1.1 1 0 0 1 1 1 0 Macoilin family BAF1_ABF1 PF04684.13 CDJ53174.1 - 8.1 5.4 41.8 11 5.0 41.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Stevor PF17410.2 CDJ53175.1 - 1.8 8.0 7.0 2.8 7.4 7.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TFIIA PF03153.13 CDJ53176.1 - 0.33 10.9 30.3 4.4 7.2 3.9 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ53176.1 - 0.43 9.2 34.1 0.015 14.0 28.1 1.6 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CDJ53176.1 - 0.61 9.0 17.6 0.27 10.1 7.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF2722 PF10846.8 CDJ53177.1 - 5.7e-06 25.5 6.7 5.7e-06 25.5 6.7 6.0 3 1 2 5 5 5 2 Protein of unknown function (DUF2722) tRNA-synt_1d PF00750.19 CDJ53177.1 - 0.00024 20.2 0.1 0.098 11.6 0.1 3.4 3 0 0 3 3 3 1 tRNA synthetases class I (R) Pex14_N PF04695.13 CDJ53177.1 - 0.013 16.2 10.8 0.013 16.2 10.8 5.7 4 1 1 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GtrA PF04138.14 CDJ53177.1 - 0.04 14.1 0.9 0.11 12.7 0.9 1.7 1 0 0 1 1 1 0 GtrA-like protein Neur_chan_memb PF02932.16 CDJ53177.1 - 0.33 11.0 42.4 0.17 11.9 4.1 4.2 4 0 0 4 4 4 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 CDJ53177.1 - 1.2 9.1 27.5 5.3 7.0 0.6 4.4 4 0 0 4 4 4 0 Protein Family FAM60A ASD2 PF08687.11 CDJ53177.1 - 7.8 6.0 47.0 0.83 9.2 8.8 4.2 4 0 0 4 4 4 0 Apx/Shroom domain ASD2 SR-25 PF10500.9 CDJ53178.1 - 0.0022 17.7 24.9 0.0027 17.4 24.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 CDJ53178.1 - 0.2 11.2 21.2 0.22 11.1 21.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SARAF PF06682.12 CDJ53178.1 - 0.57 9.8 24.4 0.73 9.4 24.4 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Apt1 PF10351.9 CDJ53178.1 - 1.8 7.3 19.9 2 7.2 19.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ53178.1 - 3.1 7.6 23.9 3.3 7.5 23.9 1.1 1 0 0 1 1 1 0 SPX domain Sin_N PF04801.13 CDJ53178.1 - 6.3 5.9 25.1 7.3 5.7 25.1 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Plasmodium_Vir PF05795.11 CDJ53178.1 - 6.7 6.0 13.4 8 5.8 13.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PNISR PF15996.5 CDJ53178.1 - 9.8 6.4 29.0 9.2 6.5 28.5 1.2 1 1 0 1 1 1 0 Arginine/serine-rich protein PNISR DALR_1 PF05746.15 CDJ53179.1 - 0.00066 19.8 0.4 0.035 14.3 0.0 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain TFIIA PF03153.13 CDJ53179.1 - 0.18 11.8 28.6 0.22 11.5 28.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ53179.1 - 0.4 9.7 19.1 0.46 9.5 19.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CCSAP PF15748.5 CDJ53179.1 - 1 9.4 24.4 1.5 8.9 24.4 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Roughex PF06020.11 CDJ53179.1 - 3.3 6.7 17.1 4.3 6.3 17.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein RE_TdeIII PF09520.10 CDJ53179.1 - 4.4 6.9 9.3 5.7 6.5 9.3 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII PepSY_2 PF13670.6 CDJ53179.1 - 5 7.2 9.0 3.9 7.5 0.4 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Chorion_2 PF03964.15 CDJ53179.1 - 5.3 7.9 23.1 13 6.7 2.2 2.8 1 1 1 2 2 2 0 Chorion family 2 Mitofilin PF09731.9 CDJ53179.1 - 5.5 5.7 21.7 6.4 5.5 21.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PPP4R2 PF09184.11 CDJ53179.1 - 5.7 6.4 19.0 6.9 6.2 19.0 1.0 1 0 0 1 1 1 0 PPP4R2 SRP-alpha_N PF04086.13 CDJ53179.1 - 8.9 6.1 21.7 11 5.9 21.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RskA PF10099.9 CDJ53180.1 - 4 7.7 0.0 4 7.7 0.0 8.4 2 2 2 5 5 5 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ53181.1 - 0.0067 16.1 6.9 0.0067 16.1 6.9 3.5 2 1 0 2 2 2 1 Spt20 family LEP503 PF15221.6 CDJ53181.1 - 0.03 14.6 0.1 0.17 12.3 0.0 2.3 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 DUF4834 PF16118.5 CDJ53181.1 - 0.14 13.1 0.4 0.14 13.1 0.4 4.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3446 PF11928.8 CDJ53181.1 - 0.31 11.4 0.0 0.31 11.4 0.0 6.5 4 1 2 6 6 6 0 Early growth response N-terminal domain Ribosomal_L2_C PF03947.18 CDJ53182.1 - 5.7e-17 62.1 5.4 1.2e-16 61.0 0.6 3.9 2 1 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CDJ53182.1 - 1.4e-09 37.8 0.6 9.3e-09 35.1 0.6 2.3 1 1 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MORN PF02493.20 CDJ53183.1 - 1.8e-30 103.0 44.3 3.9e-07 29.6 1.0 6.3 6 0 0 6 6 6 6 MORN repeat Presenilin PF01080.17 CDJ53183.1 - 0.17 10.6 7.8 0.21 10.3 7.8 1.1 1 0 0 1 1 1 0 Presenilin VIT1 PF01988.19 CDJ53183.1 - 0.33 10.8 2.2 0.52 10.1 2.2 1.3 1 0 0 1 1 1 0 VIT family Pex14_N PF04695.13 CDJ53183.1 - 0.68 10.6 14.8 1 10.0 14.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C PF13299.6 CDJ53183.1 - 2.3 8.4 7.1 3.6 7.7 7.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FmiP_Thoc5 PF09766.9 CDJ53183.1 - 2.8 7.1 13.3 3.7 6.7 13.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 NPR3 PF03666.13 CDJ53183.1 - 2.9 6.6 5.9 3.8 6.2 5.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PAT1 PF09770.9 CDJ53183.1 - 4.7 5.4 11.8 5.7 5.1 11.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4589 PF15252.6 CDJ53183.1 - 5.2 7.0 11.6 8.1 6.4 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) DUF4698 PF15769.5 CDJ53183.1 - 5.3 6.0 7.4 7.4 5.5 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Hid1 PF12722.7 CDJ53183.1 - 6.7 4.7 8.4 8.6 4.4 8.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.6 CDJ53183.1 - 6.9 5.4 7.1 8.6 5.1 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Lin-8 PF03353.15 CDJ53183.1 - 8 5.9 10.2 12 5.4 10.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pex14_N PF04695.13 CDJ53184.1 - 0.014 16.1 16.1 0.015 15.9 16.1 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Slu7 PF11708.8 CDJ53184.1 - 6.2 6.5 10.1 6.2 6.5 10.1 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor SR-25 PF10500.9 CDJ53185.1 - 0.015 14.9 16.9 0.015 14.9 16.9 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cyt_bd_oxida_II PF02322.15 CDJ53185.1 - 1.3 8.3 11.0 1.9 7.8 11.0 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II TFIIA PF03153.13 CDJ53185.1 - 5.4 6.9 26.7 0.39 10.6 21.3 1.7 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ53185.1 - 9.7 7.2 9.1 1.6 9.7 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ53186.1 - 0.45 10.5 27.9 0.6 10.1 27.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1180 PF06679.12 CDJ53187.1 - 0.086 13.3 9.2 0.094 13.1 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Senescence_reg PF04520.13 CDJ53187.1 - 1.3 9.9 12.6 1.5 9.7 12.6 1.0 1 0 0 1 1 1 0 Senescence regulator DUF4484 PF14831.6 CDJ53187.1 - 1.6 8.8 10.0 2 8.4 10.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) CCDC53 PF10152.9 CDJ53187.1 - 2.5 8.5 16.4 3 8.3 16.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FAM60A PF15396.6 CDJ53187.1 - 5.7 6.9 9.1 6.5 6.7 9.1 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Band_3_cyto PF07565.13 CDJ53187.1 - 8.8 6.0 13.6 9.6 5.9 13.6 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SARAF PF06682.12 CDJ53187.1 - 9.1 5.8 16.5 11 5.6 16.5 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis eIF-3_zeta PF05091.12 CDJ53187.1 - 9.5 5.1 15.5 11 4.8 15.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Cation_ATPase PF13246.6 CDJ53188.1 - 0.58 10.3 2.9 1.3 9.1 0.6 2.8 2 0 0 2 2 2 0 Cation transport ATPase (P-type) DUF2585 PF10755.9 CDJ53189.1 - 1.1 8.9 4.4 2 8.1 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) F-protein PF00469.20 CDJ53189.1 - 1.9 8.1 6.0 3.2 7.3 6.0 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef SPX PF03105.19 CDJ53189.1 - 5 6.9 15.4 6.2 6.6 15.4 1.0 1 0 0 1 1 1 0 SPX domain DUF747 PF05346.11 CDJ53190.1 - 4.2e-48 164.4 6.4 2.7e-21 76.4 0.3 3.0 2 1 1 3 3 3 3 Eukaryotic membrane protein family DUF2722 PF10846.8 CDJ53190.1 - 0.0033 16.4 7.3 0.004 16.2 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Dpy19 PF10034.9 CDJ53190.1 - 0.0034 15.7 0.2 0.0043 15.3 0.2 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation EPL1 PF10513.9 CDJ53190.1 - 0.059 13.7 1.6 0.083 13.3 1.6 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF2828 PF11443.8 CDJ53190.1 - 0.082 11.0 6.0 0.11 10.6 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Nckap1 PF09735.9 CDJ53190.1 - 0.18 9.8 3.0 0.23 9.4 3.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein TFIIA PF03153.13 CDJ53190.1 - 0.24 11.3 17.6 0.31 11.0 17.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Baculo_PP31 PF05311.11 CDJ53190.1 - 0.38 10.2 4.1 0.54 9.7 4.1 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Suf PF05843.14 CDJ53190.1 - 0.51 10.3 6.4 0.69 9.8 6.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 CDJ53190.1 - 0.64 8.9 8.5 0.82 8.6 8.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CCDC53 PF10152.9 CDJ53190.1 - 1 9.8 6.8 0.53 10.7 4.4 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 CDJ53190.1 - 1.1 8.8 19.8 1.7 8.2 19.8 1.3 1 0 0 1 1 1 0 Spt20 family RR_TM4-6 PF06459.12 CDJ53190.1 - 1.3 8.8 6.5 1.8 8.3 6.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GTSE1_N PF15259.6 CDJ53190.1 - 1.7 8.8 6.0 3.2 7.9 6.0 1.4 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 DUF4175 PF13779.6 CDJ53190.1 - 2.2 6.1 26.8 3.7 5.3 26.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Rrn6 PF10214.9 CDJ53190.1 - 2.4 6.5 9.9 34 2.7 12.7 1.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor TERB2 PF15101.6 CDJ53190.1 - 2.5 8.1 7.8 3.4 7.7 7.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Med15 PF09606.10 CDJ53190.1 - 2.8 6.5 25.6 3.7 6.1 25.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Folliculin PF11704.8 CDJ53190.1 - 3 7.7 9.0 4.6 7.1 9.0 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Presenilin PF01080.17 CDJ53190.1 - 6 5.5 9.6 0.059 12.1 2.0 1.6 2 0 0 2 2 2 0 Presenilin RB_A PF01858.17 CDJ53190.1 - 9.1 6.1 7.5 6.6 6.5 3.7 2.2 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain GTP_EFTU PF00009.27 CDJ53191.1 - 1.2e-32 113.1 1.2 1.2e-32 113.1 1.2 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDJ53191.1 - 5.8e-09 36.0 0.0 0.0033 17.5 0.0 2.9 2 0 0 2 2 2 2 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CDJ53191.1 - 7.9e-08 32.4 0.1 3.3e-07 30.4 0.1 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CDJ53191.1 - 0.0052 17.0 0.1 0.0052 17.0 0.1 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ53191.1 - 0.03 13.8 0.0 0.093 12.2 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CDJ53191.1 - 0.066 13.3 0.2 0.066 13.3 0.2 5.1 4 2 1 5 5 5 0 Dynamin family RsgA_GTPase PF03193.16 CDJ53191.1 - 0.087 12.7 7.1 1.3 8.9 0.0 3.4 2 1 1 3 3 3 0 RsgA GTPase EPL1 PF10513.9 CDJ53192.1 - 0.0078 16.6 6.0 0.0078 16.6 6.0 3.2 3 1 0 3 3 3 1 Enhancer of polycomb-like RskA PF10099.9 CDJ53192.1 - 0.011 16.1 1.7 0.011 16.1 1.7 5.1 1 1 3 4 4 4 0 Anti-sigma-K factor rskA BPD_transp_2 PF02653.16 CDJ53192.1 - 0.011 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component YajC PF02699.15 CDJ53192.1 - 0.047 13.6 0.1 0.047 13.6 0.1 5.9 3 2 0 3 3 3 0 Preprotein translocase subunit PTPlike_phytase PF14566.6 CDJ53192.1 - 2.9 8.0 14.9 1.1 9.4 8.1 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate EphA2_TM PF14575.6 CDJ53192.1 - 8.9 7.3 0.0 8.9 7.3 0.0 4.3 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 CDJ53193.1 - 0.92 10.5 0.0 0.92 10.5 0.0 4.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Ribosomal_L1 PF00687.21 CDJ53195.1 - 8.4e-22 77.9 0.0 1.1e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Regnase_1_C PF18561.1 CDJ53195.1 - 0.014 15.2 0.0 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain DUF4680 PF15730.5 CDJ53195.1 - 3.5 8.0 8.9 0.38 11.1 4.3 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4680) HEAT PF02985.22 CDJ53197.1 - 1.7e-11 43.3 17.2 0.00022 21.2 0.1 5.7 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 CDJ53197.1 - 6e-07 29.8 1.9 6e-07 29.8 1.9 8.0 9 0 0 9 9 9 2 HEAT repeats Cnd1 PF12717.7 CDJ53197.1 - 2.3e-05 24.5 0.0 0.0038 17.3 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Androgen_recep PF02166.16 CDJ53197.1 - 0.0012 17.8 11.7 0.0012 17.8 11.7 20.9 12 5 11 24 24 24 3 Androgen receptor AF-4 PF05110.13 CDJ53199.1 - 0.17 9.9 2.2 0.25 9.4 2.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Spt20 PF12090.8 CDJ53200.1 - 2.5 7.7 14.7 3.5 7.2 14.7 1.2 1 0 0 1 1 1 0 Spt20 family AP2 PF00847.20 CDJ53201.1 - 0.038 14.2 0.6 0.038 14.2 0.6 3.1 2 0 0 2 2 2 0 AP2 domain Na_H_Exchanger PF00999.21 CDJ53202.1 - 3.8e-06 25.9 1.8 3.8e-06 25.9 1.8 2.4 3 0 0 3 3 3 1 Sodium/hydrogen exchanger family K_channel_TID PF07941.11 CDJ53202.1 - 0.026 15.0 9.2 0.026 15.0 9.2 5.8 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Neur_chan_memb PF02932.16 CDJ53202.1 - 1.3 9.0 11.9 0.84 9.7 9.9 1.7 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ORC6 PF05460.13 CDJ53202.1 - 3.6 6.8 23.9 6.2 6.0 23.9 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Cpn10 PF00166.21 CDJ53203.1 - 9.6e-26 89.7 5.0 1.9e-19 69.5 0.0 3.7 3 0 0 3 3 3 2 Chaperonin 10 Kd subunit SpoIIIAH PF12685.7 CDJ53203.1 - 0.03 14.2 0.1 0.03 14.2 0.1 4.0 1 1 1 2 2 2 0 SpoIIIAH-like protein LicD PF04991.13 CDJ53203.1 - 1.4 9.0 0.0 1.4 9.0 0.0 4.6 4 1 0 4 4 4 0 LicD family N6_N4_Mtase PF01555.18 CDJ53205.1 - 0.008 15.9 0.1 0.068 12.9 0.1 2.0 1 1 0 1 1 1 1 DNA methylase RAP1 PF07218.11 CDJ53205.1 - 0.082 11.2 7.5 0.1 10.9 7.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RRM_1 PF00076.22 CDJ53206.1 - 4.3e-34 116.1 0.1 4.8e-17 61.6 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 CDJ53206.1 - 4.1e-06 26.8 3.6 7.5e-06 25.9 3.6 1.4 1 0 0 1 1 1 1 WW domain RRM_7 PF16367.5 CDJ53206.1 - 0.00027 21.0 0.0 0.12 12.5 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif RNA_bind PF08675.11 CDJ53206.1 - 0.0085 16.1 0.0 2.3 8.3 0.0 2.8 2 1 0 2 2 2 1 RNA binding domain Macoilin PF09726.9 CDJ53206.1 - 5.2 5.5 18.5 0.025 13.1 9.1 1.8 2 0 0 2 2 2 0 Macoilin family EOS1 PF12326.8 CDJ53206.1 - 9 6.2 5.4 2.6 7.9 0.1 2.4 2 1 0 2 2 2 0 N-glycosylation protein SNF2_N PF00176.23 CDJ53207.1 - 1.2e-08 34.1 0.1 1.2e-08 34.1 0.1 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Nop25 PF09805.9 CDJ53207.1 - 0.062 13.8 24.4 0.045 14.2 17.0 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) PAT1 PF09770.9 CDJ53207.1 - 1.8 6.7 21.8 2.4 6.3 21.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DLIC PF05783.11 CDJ53207.1 - 2.2 7.0 14.7 0.076 11.8 8.3 1.8 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) DUF4834 PF16118.5 CDJ53208.1 - 0.028 15.4 20.5 1.6 9.8 0.0 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ53208.1 - 1.6 7.4 16.0 0.036 12.8 3.4 3.0 3 0 0 3 3 3 0 Presenilin DAG_kinase_N PF14513.6 CDJ53208.1 - 7.2 6.8 11.1 1.7 8.9 3.2 3.0 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus Asp-B-Hydro_N PF05279.11 CDJ53209.1 - 6.3 6.8 33.6 6.4 6.8 10.2 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region SR-25 PF10500.9 CDJ53209.1 - 7.3 6.1 44.8 0.37 10.4 26.2 3.1 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein ESM4 PF15952.5 CDJ53210.1 - 0.057 13.8 11.0 0.062 13.7 11.0 1.0 1 0 0 1 1 1 0 Enhancer of split M4 family DUF4400 PF14348.6 CDJ53210.1 - 1.5 8.3 3.4 1.8 8.0 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) DUF1980 PF09323.10 CDJ53210.1 - 2.9 7.8 5.5 3.2 7.6 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Spt20 PF12090.8 CDJ53210.1 - 5.4 6.5 25.5 6.2 6.4 25.5 1.1 1 0 0 1 1 1 0 Spt20 family IQ PF00612.27 CDJ53211.1 - 0.044 13.6 1.7 0.046 13.5 0.1 1.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif TPR_9 PF13371.6 CDJ53213.1 - 2.2e-08 34.1 0.3 2.2e-08 34.1 0.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ53213.1 - 9.6e-08 32.4 0.7 9.6e-08 32.4 0.7 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ53213.1 - 3e-07 30.1 0.6 0.15 12.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ53213.1 - 7.8e-07 28.7 0.2 0.017 15.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ53213.1 - 0.00045 20.8 8.2 0.0041 17.8 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ53213.1 - 0.00052 20.0 0.2 0.037 14.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ53213.1 - 0.0051 17.4 1.2 0.063 13.9 0.1 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ53213.1 - 0.0067 17.1 9.9 0.01 16.5 0.4 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ53213.1 - 0.0075 16.3 0.1 3.3 7.9 0.0 3.1 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CDJ53213.1 - 0.011 16.0 0.9 0.041 14.1 0.9 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CDJ53213.1 - 0.11 12.9 0.3 0.34 11.4 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ53213.1 - 0.18 12.5 0.2 0.18 12.5 0.2 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF725 PF05267.12 CDJ53213.1 - 3.9 7.5 7.7 10 6.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF725) Abhydrolase_2 PF02230.16 CDJ53214.1 - 5.8e-48 163.5 0.0 1.2e-47 162.5 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CDJ53214.1 - 3.7e-06 27.7 0.1 1.7e-05 25.5 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDJ53214.1 - 0.00013 21.9 0.0 0.00063 19.7 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ53214.1 - 0.00043 19.8 0.1 0.06 12.8 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ53214.1 - 0.0025 17.5 0.0 0.0075 15.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 CDJ53214.1 - 0.0036 16.8 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase FSH1 PF03959.13 CDJ53214.1 - 0.0044 16.7 0.0 0.01 15.5 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 CDJ53214.1 - 0.0063 15.8 0.8 0.84 8.9 0.2 3.0 2 1 1 3 3 3 1 Serine aminopeptidase, S33 AXE1 PF05448.12 CDJ53214.1 - 0.038 12.6 0.1 0.061 12.0 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 CDJ53214.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) SET PF00856.28 CDJ53215.1 - 0.027 14.9 0.1 0.086 13.2 0.0 2.0 2 0 0 2 2 2 0 SET domain Apt1 PF10351.9 CDJ53215.1 - 0.031 13.2 4.5 0.051 12.4 4.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ53215.1 - 0.077 12.9 5.0 0.11 12.4 3.6 1.9 2 0 0 2 2 2 0 SPX domain Spt20 PF12090.8 CDJ53215.1 - 0.34 10.5 5.3 0.66 9.5 0.3 2.3 2 0 0 2 2 2 0 Spt20 family GATA PF00320.27 CDJ53217.1 - 6.7e-07 28.8 3.6 1.3e-06 27.8 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Pyrophosphatase PF00719.19 CDJ53218.1 - 0.00046 20.0 0.1 0.00046 20.0 0.1 1.5 2 0 0 2 2 2 1 Inorganic pyrophosphatase Rxt3 PF08642.10 CDJ53218.1 - 0.24 12.2 3.9 0.26 12.0 3.9 1.0 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Coilin_N PF15862.5 CDJ53218.1 - 0.29 10.9 12.3 0.32 10.8 12.3 1.0 1 0 0 1 1 1 0 Coilin N-terminus FYDLN_acid PF09538.10 CDJ53218.1 - 0.4 11.4 8.3 0.44 11.2 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Spt20 PF12090.8 CDJ53218.1 - 0.45 10.1 30.4 0.44 10.1 30.4 1.0 1 0 0 1 1 1 0 Spt20 family DUF4820 PF16091.5 CDJ53218.1 - 1.2 8.5 9.1 1.2 8.4 9.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CobT PF06213.12 CDJ53218.1 - 1.3 8.4 16.2 1.3 8.4 16.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CPSF100_C PF13299.6 CDJ53218.1 - 1.6 8.9 10.6 1.7 8.8 10.6 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4834 PF16118.5 CDJ53218.1 - 1.6 9.8 13.5 1.8 9.6 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ53218.1 - 2.9 6.6 11.5 2.7 6.7 11.5 1.0 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ53218.1 - 3.6 7.5 26.0 3.6 7.5 26.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ53218.1 - 4 6.3 14.9 3.7 6.4 14.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ53218.1 - 5.2 4.9 10.0 4.7 5.0 10.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SpoIIP PF07454.11 CDJ53218.1 - 7.2 6.0 14.0 7.2 6.0 14.0 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EIIBC-GUT_N PF03612.14 CDJ53218.1 - 9.3 6.0 11.1 10 5.9 11.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Connexin PF00029.19 CDJ53218.1 - 9.5 5.9 8.6 9.4 5.9 8.6 1.0 1 0 0 1 1 1 0 Connexin RIFIN PF02009.16 CDJ53219.1 - 0.057 13.3 0.3 0.071 13.0 0.3 1.2 1 0 0 1 1 1 0 Rifin Menin PF05053.13 CDJ53219.1 - 3.8 5.8 10.6 5 5.4 10.6 1.3 1 0 0 1 1 1 0 Menin CSG2 PF16965.5 CDJ53219.1 - 7.8 5.3 6.7 7.2 5.5 6.0 1.3 1 1 0 1 1 1 0 Ceramide synthase regulator SARAF PF06682.12 CDJ53220.1 - 0.0058 16.3 7.5 0.0058 16.3 7.5 5.0 2 1 2 4 4 4 1 SOCE-associated regulatory factor of calcium homoeostasis Spt20 PF12090.8 CDJ53221.1 - 0.0059 16.2 22.6 0.0059 16.2 22.6 3.0 1 1 1 3 3 1 1 Spt20 family GREB1 PF15782.5 CDJ53221.1 - 0.0067 13.6 30.6 0.008 13.4 30.6 1.0 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer DUF3995 PF13160.6 CDJ53221.1 - 0.0082 16.5 0.4 0.014 15.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3995) PAT1 PF09770.9 CDJ53221.1 - 0.14 10.4 43.8 0.19 10.0 43.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dapper PF15268.6 CDJ53221.1 - 0.19 10.5 34.5 0.23 10.3 34.5 1.1 1 0 0 1 1 1 0 Dapper WTX PF09422.10 CDJ53221.1 - 0.35 9.9 21.3 0.47 9.5 21.3 1.2 1 0 0 1 1 1 0 WTX protein SAPS PF04499.15 CDJ53221.1 - 0.52 9.0 19.3 0.69 8.6 19.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Utp14 PF04615.13 CDJ53221.1 - 0.85 8.1 30.7 1.1 7.7 30.7 1.1 1 0 0 1 1 1 0 Utp14 protein Hamartin PF04388.12 CDJ53221.1 - 0.85 8.2 28.4 1 7.9 28.4 1.1 1 0 0 1 1 1 0 Hamartin protein PAP2 PF01569.21 CDJ53221.1 - 0.9 9.3 6.7 0.16 11.7 2.7 1.8 1 1 1 2 2 2 0 PAP2 superfamily FAM220 PF15487.6 CDJ53221.1 - 0.92 9.1 23.6 0.061 12.9 17.6 1.7 2 0 0 2 2 2 0 FAM220 family SOG2 PF10428.9 CDJ53221.1 - 1.1 8.4 29.7 1.6 7.9 29.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein LptF_LptG PF03739.14 CDJ53221.1 - 1.1 8.0 6.3 1.7 7.4 6.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Draxin PF15550.6 CDJ53221.1 - 1.3 8.8 25.0 1.7 8.4 25.0 1.1 1 0 0 1 1 1 0 Draxin Nucleoside_tran PF01733.18 CDJ53221.1 - 1.7 7.9 7.0 0.069 12.5 1.1 1.6 2 0 0 2 2 2 0 Nucleoside transporter LAP1C PF05609.12 CDJ53221.1 - 1.8 7.6 29.1 2.4 7.2 29.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Mitofilin PF09731.9 CDJ53221.1 - 2.4 6.9 38.1 0.019 13.8 24.7 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein KAR9 PF08580.10 CDJ53221.1 - 4.6 5.7 21.1 5.6 5.4 21.1 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SPX PF03105.19 CDJ53221.1 - 6.6 6.5 32.1 8.9 6.1 32.1 1.1 1 0 0 1 1 1 0 SPX domain Ssl1 PF04056.14 CDJ53222.1 - 6.4e-26 91.4 2.6 3.3e-14 53.1 0.3 2.9 3 0 0 3 3 3 2 Ssl1-like VWA_2 PF13519.6 CDJ53222.1 - 2.4e-06 28.1 0.0 7.5e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain SOG2 PF10428.9 CDJ53222.1 - 0.019 14.2 34.3 0.34 10.0 33.5 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein SPX PF03105.19 CDJ53222.1 - 8.6 6.2 43.6 2.7 7.8 37.5 2.0 2 0 0 2 2 2 0 SPX domain FliT PF05400.13 CDJ53223.1 - 0.044 14.6 9.7 0.044 14.6 9.7 2.5 1 1 1 2 2 2 0 Flagellar protein FliT DDHD PF02862.17 CDJ53223.1 - 0.47 10.6 6.5 0.81 9.8 6.5 1.4 1 0 0 1 1 1 0 DDHD domain DEAD PF00270.29 CDJ53224.1 - 1.7e-51 174.5 0.0 3.1e-51 173.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ53224.1 - 5.2e-34 116.9 0.0 2.1e-33 115.0 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 CDJ53224.1 - 0.0068 15.2 0.1 0.019 13.8 0.0 1.7 3 0 0 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 CDJ53224.1 - 0.024 14.9 0.0 0.9 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain TFIIA PF03153.13 CDJ53224.1 - 3.8 7.4 17.6 7.8 6.4 13.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ53225.1 - 0.00095 19.5 9.4 0.00095 19.5 9.4 24.2 2 2 6 8 8 8 1 Anti-sigma-K factor rskA AT_hook PF02178.19 CDJ53225.1 - 1.1 9.4 5.4 2.3 8.4 5.4 1.6 1 0 0 1 1 1 0 AT hook motif Coiled PF05710.12 CDJ53225.1 - 4.9 8.1 21.7 3.7 8.4 4.7 3.4 3 0 0 3 3 3 0 Coiled coil RskA PF10099.9 CDJ53226.1 - 1.1e-05 25.8 7.3 1.1e-05 25.8 7.3 2.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF2207 PF09972.9 CDJ53226.1 - 0.00018 20.4 0.2 0.00026 19.9 0.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) OmpH PF03938.14 CDJ53226.1 - 0.02 15.3 21.8 0.02 15.3 21.8 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CLN3 PF02487.17 CDJ53226.1 - 0.067 12.2 3.2 0.12 11.4 3.2 1.4 1 0 0 1 1 1 0 CLN3 protein EOS1 PF12326.8 CDJ53226.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 N-glycosylation protein Suf PF05843.14 CDJ53226.1 - 0.33 10.9 10.4 0.2 11.6 8.7 1.4 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) CAF1 PF04857.20 CDJ53226.1 - 0.39 9.8 4.5 0.58 9.3 4.5 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease O-antigen_lig PF13425.6 CDJ53226.1 - 1.4 7.6 7.2 1.9 7.1 7.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4569 PF15133.6 CDJ53226.1 - 1.5 8.5 12.0 0.32 10.7 8.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) LMBR1 PF04791.16 CDJ53226.1 - 1.6 7.5 2.9 2.1 7.2 2.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1180 PF06679.12 CDJ53226.1 - 3.8 7.9 19.9 0.67 10.3 4.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) DUF4011 PF13195.6 CDJ53226.1 - 5.5 6.9 10.1 0.65 9.9 6.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Pheromone PF08015.11 CDJ53226.1 - 7 7.8 7.0 40 5.3 0.4 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone Pepsin-I3 PF06394.13 CDJ53226.1 - 7.4 6.8 12.8 16 5.8 12.8 1.5 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain RskA PF10099.9 CDJ53227.1 - 0.69 10.2 34.4 1.1e+02 3.0 34.4 2.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ53228.1 - 6.8e-06 26.5 39.8 0.00093 19.5 10.7 2.7 2 1 0 2 2 2 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ53228.1 - 0.0041 16.8 12.9 0.0041 16.8 12.9 2.3 2 0 0 2 2 2 1 Spt20 family Suf PF05843.14 CDJ53228.1 - 0.2 11.6 20.7 0.68 9.9 4.8 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) V_ATPase_I PF01496.19 CDJ53228.1 - 0.45 8.4 14.5 0.043 11.7 2.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 CDJ53228.1 - 2.1 6.6 6.4 4.6 5.5 0.8 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ53228.1 - 2.7 6.8 14.5 1.4 7.7 2.8 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) FPN1 PF06963.12 CDJ53228.1 - 5.1 5.5 8.1 1.5 7.3 1.3 2.3 2 0 0 2 2 2 0 Ferroportin1 (FPN1) CLN3 PF02487.17 CDJ53228.1 - 8 5.4 9.0 3.1 6.8 0.8 2.3 2 0 0 2 2 2 0 CLN3 protein PA26 PF04636.13 CDJ53228.1 - 9 5.1 13.6 3.3 6.5 4.9 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Pkinase PF00069.25 CDJ53230.1 - 0.00014 21.3 0.1 0.00014 21.3 0.1 1.9 2 1 0 2 2 2 1 Protein kinase domain TFIIA PF03153.13 CDJ53230.1 - 0.0055 16.8 21.8 0.0065 16.5 21.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit eIF3_subunit PF08597.10 CDJ53230.1 - 0.044 13.7 7.2 0.066 13.1 7.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DDRGK PF09756.9 CDJ53230.1 - 0.11 12.1 12.6 0.13 11.8 12.6 1.1 1 0 0 1 1 1 0 DDRGK domain Presenilin PF01080.17 CDJ53230.1 - 0.17 10.6 9.6 0.18 10.6 9.6 1.0 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ53230.1 - 0.54 9.8 17.9 1.3 8.5 17.9 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 CDJ53230.1 - 0.61 9.6 14.8 0.77 9.3 14.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 CDJ53230.1 - 0.8 8.7 6.7 0.93 8.4 6.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Ndc1_Nup PF09531.10 CDJ53230.1 - 1.7 7.2 10.9 2 7.0 10.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 CDJ53230.1 - 1.7 7.0 9.4 1.9 6.8 9.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Big_2 PF02368.18 CDJ53230.1 - 2.4 8.1 8.4 0.42 10.5 0.4 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) GREB1 PF15782.5 CDJ53230.1 - 4 4.4 13.7 4.7 4.2 13.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TALPID3 PF15324.6 CDJ53230.1 - 4.3 4.9 16.2 5.3 4.6 16.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target PAT1 PF09770.9 CDJ53230.1 - 5.3 5.2 19.9 5.7 5.1 19.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HGTP_anticodon2 PF12745.7 CDJ53230.1 - 5.7 6.4 11.3 7.5 6.0 11.3 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs eIF-3_zeta PF05091.12 CDJ53230.1 - 7.9 5.3 13.7 10 5.0 13.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ53230.1 - 9.2 6.2 7.2 10 6.1 7.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SMC_N PF02463.19 CDJ53232.1 - 6.8e-07 28.9 4.1 6.8e-07 28.9 4.1 2.1 1 1 1 2 2 1 1 RecF/RecN/SMC N terminal domain TMEM51 PF15345.6 CDJ53232.1 - 0.00041 20.3 2.5 0.00041 20.3 2.5 3.1 2 1 1 3 3 1 1 Transmembrane protein 51 Presenilin PF01080.17 CDJ53232.1 - 0.0032 16.3 40.0 0.083 11.6 30.7 2.0 2 0 0 2 2 2 2 Presenilin DUF3295 PF11702.8 CDJ53232.1 - 0.011 15.2 31.9 0.074 12.4 22.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) BORG_CEP PF14957.6 CDJ53232.1 - 0.017 16.3 26.0 0.21 12.7 0.4 2.1 2 0 0 2 2 2 0 Cdc42 effector AAA_21 PF13304.6 CDJ53232.1 - 0.026 14.3 0.8 0.035 13.9 0.2 1.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Ndc1_Nup PF09531.10 CDJ53232.1 - 0.032 12.9 27.0 0.047 12.4 27.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 CDJ53232.1 - 0.045 11.9 29.8 0.061 11.4 29.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RBM39linker PF15519.6 CDJ53232.1 - 0.079 14.1 1.8 0.079 14.1 1.8 3.2 2 1 0 2 2 1 0 linker between RRM2 and RRM3 domains in RBM39 protein SLD3 PF08639.10 CDJ53232.1 - 0.085 11.6 26.5 5.9 5.5 26.5 2.0 1 1 0 1 1 1 0 DNA replication regulator SLD3 V_ATPase_I PF01496.19 CDJ53232.1 - 0.094 10.6 33.7 0.34 8.8 24.4 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Band_3_cyto PF07565.13 CDJ53232.1 - 0.098 12.4 33.5 0.18 11.6 1.4 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain AAA_29 PF13555.6 CDJ53232.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain EBP50_C PF09007.11 CDJ53232.1 - 0.34 11.9 24.8 1.1 10.2 16.0 2.3 2 0 0 2 2 2 0 EBP50, C-terminal TT_ORF1 PF02956.14 CDJ53232.1 - 0.74 8.4 24.7 2 7.0 17.6 2.1 2 0 0 2 2 2 0 TT viral orf 1 Nha1_C PF08619.10 CDJ53232.1 - 0.77 8.9 33.3 1.6 7.9 22.4 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus FAM76 PF16046.5 CDJ53232.1 - 1 8.6 37.0 0.45 9.8 2.1 2.2 2 0 0 2 2 2 0 FAM76 protein CSRNP_N PF16019.5 CDJ53232.1 - 1.2 9.0 33.2 0.52 10.2 1.4 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus AbLIM_anchor PF16182.5 CDJ53232.1 - 1.7 8.4 25.6 4.5 7.0 17.5 2.0 2 0 0 2 2 2 0 Putative adherens-junction anchoring region of AbLIM Na_trans_assoc PF06512.13 CDJ53232.1 - 2.2 8.5 21.1 0.89 9.8 0.4 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated UPF0565 PF10561.9 CDJ53232.1 - 2.3 7.3 21.6 7.2 5.7 16.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Kinesin PF00225.23 CDJ53232.1 - 3 6.7 22.7 0.55 9.1 12.8 2.0 2 0 0 2 2 2 0 Kinesin motor domain HemX PF04375.14 CDJ53232.1 - 3.3 6.9 72.0 0.63 9.3 50.0 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase CCSAP PF15748.5 CDJ53232.1 - 3.3 7.8 43.1 1.2 9.3 2.0 2.0 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated XRN_M PF17846.1 CDJ53232.1 - 3.9 6.3 28.2 2.3 7.1 0.2 2.0 2 0 0 2 2 2 0 Xrn1 helical domain Trs65 PF12735.7 CDJ53232.1 - 4.2 6.7 17.3 6.3 6.1 17.3 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 NPR3 PF03666.13 CDJ53232.1 - 5.1 5.8 35.7 1 8.1 24.0 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Velvet PF11754.8 CDJ53232.1 - 8.1 6.3 38.1 1.2 9.0 2.6 2.1 2 0 0 2 2 2 0 Velvet factor Membralin PF09746.9 CDJ53232.1 - 8.3 5.3 26.9 2.9 6.8 0.4 2.0 2 0 0 2 2 2 0 Tumour-associated protein DAG_kinase_N PF14513.6 CDJ53232.1 - 9.8 6.3 38.1 1.3 9.2 1.4 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus SR-25 PF10500.9 CDJ53233.1 - 0.0016 18.1 14.2 0.0016 18.1 14.2 9.7 6 2 3 9 9 9 4 Nuclear RNA-splicing-associated protein DUF3240 PF11582.8 CDJ53235.1 - 0.0018 18.4 0.2 2.3 8.4 0.0 3.4 2 1 2 4 4 4 3 Protein of unknown function (DUF3240) tRNA-synt_2 PF00152.20 CDJ53236.1 - 1.1e-78 264.5 0.0 1.5e-78 264.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ53236.1 - 1.4e-10 41.0 0.0 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDJ53236.1 - 1.1e-07 31.6 0.0 6.5e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) NARP1 PF12569.8 CDJ53236.1 - 4 6.2 9.2 6.7 5.5 9.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Radical_SAM PF04055.21 CDJ53237.1 - 2.8e-18 66.9 0.0 7.3e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Radical_SAM_C PF16199.5 CDJ53237.1 - 1.3e-16 60.4 0.0 3.4e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Radical_SAM C-terminal domain UCH PF00443.29 CDJ53238.1 - 1.4e-33 116.5 0.4 1.3e-29 103.5 0.0 3.4 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ53238.1 - 1.6e-07 31.2 8.7 4.7e-07 29.7 0.2 3.9 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase tRNA-synt_2c PF01411.19 CDJ53239.1 - 3.8e-199 662.8 0.0 4.6e-199 662.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CDJ53239.1 - 3.9e-16 58.9 0.0 9.1e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CDJ53239.1 - 3.7e-05 24.2 0.4 0.00011 22.7 0.4 1.7 1 0 0 1 1 1 1 DHHA1 domain RRM_1 PF00076.22 CDJ53240.1 - 1.8e-26 91.7 0.5 3.1e-10 39.7 0.0 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ53240.1 - 3e-06 27.2 0.0 0.0013 18.8 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif BSD PF03909.17 CDJ53242.1 - 8.4e-07 28.9 0.2 1.6e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 BSD domain ANAPC4_WD40 PF12894.7 CDJ53244.1 - 8.7e-07 29.2 0.0 5.1e-05 23.5 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ53244.1 - 0.00011 23.0 0.1 0.056 14.3 0.0 3.2 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF4667 PF15700.5 CDJ53244.1 - 0.0075 16.4 10.0 0.044 13.9 7.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) MID_MedPIWI PF18296.1 CDJ53244.1 - 0.018 14.9 1.0 0.05 13.4 1.1 1.7 2 0 0 2 2 2 0 MID domain of medPIWI Apt1 PF10351.9 CDJ53244.1 - 0.085 11.7 4.2 0.14 11.0 4.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.13 CDJ53244.1 - 0.16 12.5 21.1 0.25 11.9 15.2 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain TraT PF05818.12 CDJ53244.1 - 0.47 10.1 10.3 0.76 9.4 10.3 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Myc_N PF01056.18 CDJ53244.1 - 0.61 9.9 8.7 14 5.5 0.0 2.1 2 0 0 2 2 2 0 Myc amino-terminal region Cwf_Cwc_15 PF04889.12 CDJ53244.1 - 0.69 9.6 3.3 0.29 10.8 0.3 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RIFIN PF02009.16 CDJ53244.1 - 0.77 9.6 3.4 1.1 9.1 3.4 1.2 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 CDJ53244.1 - 1.5 7.3 9.1 2.6 6.5 9.1 1.4 1 0 0 1 1 1 0 Macoilin family FlgH PF02107.16 CDJ53244.1 - 5.1 6.7 10.8 0.5 10.0 6.5 1.5 2 0 0 2 2 2 0 Flagellar L-ring protein PAP1 PF08601.10 CDJ53244.1 - 8.8 5.9 21.3 0.047 13.4 11.8 1.7 2 0 0 2 2 2 0 Transcription factor PAP1 BAF1_ABF1 PF04684.13 CDJ53244.1 - 10 5.1 7.0 15 4.5 7.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor eIF3_p135 PF12807.7 CDJ53246.1 - 0.0038 17.3 0.6 0.0044 17.1 0.6 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 DUF4175 PF13779.6 CDJ53246.1 - 0.0059 14.6 7.1 0.0055 14.7 7.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) DUF1249 PF06853.12 CDJ53246.1 - 0.0064 16.5 1.7 0.0087 16.1 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1249) TFIIA PF03153.13 CDJ53246.1 - 0.012 15.7 12.7 0.012 15.7 12.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cas1_AcylT PF07779.12 CDJ53246.1 - 0.013 14.5 0.2 0.015 14.2 0.2 1.0 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p Med15 PF09606.10 CDJ53246.1 - 0.015 14.0 11.8 0.014 14.1 11.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.14 CDJ53246.1 - 0.017 15.1 4.2 0.018 15.1 4.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4820 PF16091.5 CDJ53246.1 - 0.018 14.4 1.4 0.02 14.3 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Baculo_PP31 PF05311.11 CDJ53246.1 - 0.02 14.4 1.0 0.022 14.2 1.0 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF2722 PF10846.8 CDJ53246.1 - 0.022 13.7 16.1 0.026 13.5 16.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) HA2 PF04408.23 CDJ53246.1 - 0.042 14.1 2.5 0.054 13.8 2.5 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) Spt20 PF12090.8 CDJ53246.1 - 0.043 13.4 19.8 0.05 13.2 19.8 1.1 1 0 0 1 1 1 0 Spt20 family EIIBC-GUT_N PF03612.14 CDJ53246.1 - 0.064 13.0 1.9 0.075 12.8 1.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4834 PF16118.5 CDJ53246.1 - 0.086 13.8 4.3 0.1 13.6 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RskA PF10099.9 CDJ53246.1 - 0.12 12.6 4.2 0.14 12.4 4.2 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Presenilin PF01080.17 CDJ53246.1 - 0.16 10.7 2.1 0.17 10.6 2.1 1.1 1 0 0 1 1 1 0 Presenilin MRP-S27 PF10037.9 CDJ53246.1 - 0.18 10.6 8.5 0.22 10.3 8.5 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Ketoacyl-synt_2 PF13723.6 CDJ53246.1 - 0.22 11.1 6.9 0.27 10.9 6.9 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DUF3371 PF11851.8 CDJ53246.1 - 0.26 12.4 7.4 0.31 12.2 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Activator_LAG-3 PF11498.8 CDJ53246.1 - 0.28 10.1 24.9 0.31 10.0 24.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF2368 PF10166.9 CDJ53246.1 - 0.31 10.6 9.3 0.49 10.0 9.3 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) TERB2 PF15101.6 CDJ53246.1 - 0.33 11.0 7.5 0.38 10.8 7.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Roughex PF06020.11 CDJ53246.1 - 0.57 9.2 11.2 0.74 8.8 11.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein TMEM208_SND2 PF05620.11 CDJ53246.1 - 0.88 9.3 5.5 1.1 9.0 5.5 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Androgen_recep PF02166.16 CDJ53246.1 - 1.2 7.9 17.6 1.7 7.4 17.6 1.3 1 0 0 1 1 1 0 Androgen receptor PigN PF04987.14 CDJ53246.1 - 1.7 7.4 3.3 2.1 7.1 3.3 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF3464 PF11947.8 CDJ53246.1 - 1.9 8.2 5.5 2.5 7.8 5.5 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 UPF0560 PF10577.9 CDJ53246.1 - 2.5 6.5 10.9 2.8 6.3 10.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 WRNPLPNID PF15017.6 CDJ53246.1 - 3.1 8.7 8.6 4.6 8.2 8.6 1.2 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF5349 PF17298.2 CDJ53246.1 - 4.9 6.8 10.7 5.9 6.5 10.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Rpp20 PF12328.8 CDJ53246.1 - 7.2 6.6 8.4 9.5 6.2 8.4 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P mRNA_triPase PF02940.15 CDJ53248.1 - 5.3e-14 52.5 0.0 0.00046 20.0 0.0 3.2 3 0 0 3 3 3 3 mRNA capping enzyme, beta chain Med15 PF09606.10 CDJ53249.1 - 0.0011 17.7 21.3 0.0012 17.7 21.3 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PTPRCAP PF15713.5 CDJ53249.1 - 0.002 18.5 2.9 0.0021 18.3 2.9 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated DUF2722 PF10846.8 CDJ53249.1 - 0.0021 17.1 20.8 0.0022 17.0 20.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ53249.1 - 0.0024 17.5 27.0 0.0031 17.2 27.0 1.2 1 0 0 1 1 1 1 Spt20 family Eapp_C PF10238.9 CDJ53249.1 - 0.0069 16.5 5.5 0.009 16.1 5.5 1.1 1 0 0 1 1 1 1 E2F-associated phosphoprotein DUF4175 PF13779.6 CDJ53249.1 - 0.0089 14.0 13.5 0.0088 14.0 13.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) TFIIA PF03153.13 CDJ53249.1 - 0.018 15.1 25.4 0.02 14.9 25.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BRF1 PF07741.13 CDJ53249.1 - 0.036 14.4 5.1 0.048 14.0 5.1 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Pex14_N PF04695.13 CDJ53249.1 - 0.058 14.1 15.1 0.067 13.8 15.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF_4EBP PF05456.11 CDJ53249.1 - 0.063 13.2 8.0 0.11 12.5 8.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) RR_TM4-6 PF06459.12 CDJ53249.1 - 0.066 13.0 3.8 0.062 13.1 3.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TERB2 PF15101.6 CDJ53249.1 - 0.072 13.1 9.1 0.08 13.0 9.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Peptidase_S49_N PF08496.10 CDJ53249.1 - 0.1 12.7 2.6 0.11 12.6 2.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Suf PF05843.14 CDJ53249.1 - 0.1 12.6 10.8 0.1 12.6 10.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EPL1 PF10513.9 CDJ53249.1 - 0.1 13.0 6.0 0.11 12.9 6.0 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like SpoIIP PF07454.11 CDJ53249.1 - 0.11 12.0 5.7 0.11 11.9 5.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Band_3_cyto PF07565.13 CDJ53249.1 - 0.12 12.2 4.4 0.12 12.1 4.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Connexin PF00029.19 CDJ53249.1 - 0.14 11.9 1.1 0.14 11.9 1.1 1.2 1 0 0 1 1 1 0 Connexin eIF-3_zeta PF05091.12 CDJ53249.1 - 0.15 11.0 9.3 0.16 10.9 9.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UPF0560 PF10577.9 CDJ53249.1 - 0.18 10.3 14.6 0.19 10.2 14.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Presenilin PF01080.17 CDJ53249.1 - 0.22 10.3 7.0 0.22 10.3 7.0 1.1 1 0 0 1 1 1 0 Presenilin Activator_LAG-3 PF11498.8 CDJ53249.1 - 0.28 10.1 30.6 0.33 9.9 30.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ALMT PF11744.8 CDJ53249.1 - 0.3 9.9 3.4 0.33 9.7 3.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CPSF100_C PF13299.6 CDJ53249.1 - 0.3 11.3 6.2 0.35 11.0 6.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ctr PF04145.15 CDJ53249.1 - 0.31 11.7 2.6 0.32 11.6 2.6 1.2 1 0 0 1 1 1 0 Ctr copper transporter family SOG2 PF10428.9 CDJ53249.1 - 0.32 10.1 10.2 0.36 10.0 10.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein V_ATPase_I PF01496.19 CDJ53249.1 - 0.35 8.7 4.8 0.39 8.6 4.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 CDJ53249.1 - 0.36 10.1 6.4 0.4 10.0 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 CDJ53249.1 - 0.37 10.8 6.0 0.4 10.7 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ53249.1 - 0.39 9.7 2.4 0.39 9.7 2.4 1.1 1 0 0 1 1 1 0 CLN3 protein PAT1 PF09770.9 CDJ53249.1 - 0.51 8.5 17.5 0.53 8.5 17.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TMEM51 PF15345.6 CDJ53249.1 - 0.74 9.6 9.2 0.9 9.3 9.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Endostatin PF06482.11 CDJ53249.1 - 0.74 9.2 11.5 0.9 8.9 11.5 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Roughex PF06020.11 CDJ53249.1 - 0.84 8.7 11.5 0.96 8.5 11.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF688 PF05097.12 CDJ53249.1 - 0.86 8.7 9.3 1.1 8.4 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Hid1 PF12722.7 CDJ53249.1 - 1.4 7.0 6.3 1.4 6.9 6.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 CDJ53249.1 - 1.6 7.4 7.6 1.6 7.3 7.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EIIBC-GUT_N PF03612.14 CDJ53249.1 - 1.8 8.3 6.9 2.2 8.0 6.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3464 PF11947.8 CDJ53249.1 - 2.7 7.7 9.2 3.6 7.3 9.2 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 GREB1 PF15782.5 CDJ53249.1 - 3.4 4.7 9.8 3.5 4.6 9.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4834 PF16118.5 CDJ53249.1 - 3.4 8.7 13.5 4.9 8.2 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) GET2 PF08690.10 CDJ53249.1 - 3.5 7.2 11.6 4.5 6.9 11.6 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 PepSY_TM PF03929.16 CDJ53249.1 - 4.9 6.7 5.6 5.5 6.6 5.6 1.3 1 0 0 1 1 1 0 PepSY-associated TM region EOS1 PF12326.8 CDJ53249.1 - 6.3 6.7 6.1 0.67 9.9 2.0 1.4 2 0 0 2 2 1 0 N-glycosylation protein DUF2417 PF10329.9 CDJ53249.1 - 7.3 5.9 5.3 9.4 5.6 5.3 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Peptidase_M22 PF00814.25 CDJ53250.1 - 2e-08 34.3 18.2 2.1e-05 24.4 3.3 5.0 5 0 0 5 5 5 3 Glycoprotease family DUF2722 PF10846.8 CDJ53250.1 - 0.0011 18.0 0.5 0.0011 18.0 0.5 6.5 5 2 0 5 5 5 2 Protein of unknown function (DUF2722) MITF_TFEB_C_3_N PF15951.5 CDJ53250.1 - 0.0086 16.7 6.4 0.0086 16.7 6.4 8.8 7 1 2 9 9 9 1 MITF/TFEB/TFEC/TFE3 N-terminus SPX PF03105.19 CDJ53250.1 - 0.051 13.5 0.0 0.051 13.5 0.0 3.6 1 1 0 2 2 2 0 SPX domain DUF2052 PF09747.9 CDJ53250.1 - 0.52 10.4 28.3 0.17 12.0 12.4 4.1 4 0 0 4 4 4 0 Coiled-coil domain containing protein (DUF2052) SID-1_RNA_chan PF13965.6 CDJ53250.1 - 2.9 6.2 8.3 0.56 8.6 3.7 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 ALMT PF11744.8 CDJ53250.1 - 6.3 5.5 23.3 0.88 8.3 0.3 3.2 3 0 0 3 3 3 0 Aluminium activated malate transporter RVT_1 PF00078.27 CDJ53251.1 - 1e-06 28.5 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ53252.1 - 1.2e-08 35.4 0.0 2.9e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ53252.1 - 2.2e-08 34.5 0.0 5.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 CDJ53252.1 - 3.3e-08 33.5 0.1 8.4e-08 32.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 CDJ53252.1 - 5.8e-07 29.3 0.0 2.1e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease P34-Arc PF04045.14 CDJ53252.1 - 0.04 13.6 1.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Arp2/3 complex, 34 kD subunit p34-Arc TipAS PF07739.13 CDJ53252.1 - 0.051 14.1 2.7 0.3 11.6 0.1 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain RVP PF00077.20 CDJ53252.1 - 0.095 13.0 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2330 PF10092.9 CDJ53252.1 - 0.096 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) DUF4667 PF15700.5 CDJ53253.1 - 5.5e-05 23.4 37.6 0.25 11.4 3.9 5.4 5 0 0 5 5 5 5 Domain of unknown function (DUF4667) Activator_LAG-3 PF11498.8 CDJ53253.1 - 0.0023 17.0 12.0 0.0023 17.0 12.0 4.4 4 0 0 4 4 4 2 Transcriptional activator LAG-3 SR-25 PF10500.9 CDJ53253.1 - 0.054 13.1 93.0 0.027 14.1 3.7 5.9 5 1 0 5 5 5 0 Nuclear RNA-splicing-associated protein Trypan_PARP PF05887.11 CDJ53254.1 - 0.0011 19.0 17.4 0.0011 19.0 17.4 1.8 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Androgen_recep PF02166.16 CDJ53254.1 - 0.35 9.7 20.0 0.62 8.8 20.0 1.4 1 0 0 1 1 1 0 Androgen receptor Grg1 PF11034.8 CDJ53254.1 - 5.1 7.4 23.4 5.9 7.2 12.0 2.9 1 1 1 2 2 2 0 Glucose-repressible protein Grg1 RSB_motif PF16294.5 CDJ53255.1 - 0.0076 16.5 5.5 0.0094 16.2 5.5 1.1 1 0 0 1 1 1 1 RNSP1-SAP18 binding (RSB) motif TFIIA PF03153.13 CDJ53255.1 - 0.021 14.8 32.4 0.024 14.7 32.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 CDJ53255.1 - 0.026 14.7 9.5 0.039 14.1 9.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 CDJ53255.1 - 0.031 14.0 5.3 0.032 14.0 5.3 1.1 1 0 0 1 1 1 0 Connexin AF-4 PF05110.13 CDJ53255.1 - 0.039 12.1 15.1 0.041 12.0 15.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Zip PF02535.22 CDJ53255.1 - 0.041 13.1 9.6 0.044 13.0 9.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 CDJ53255.1 - 0.048 11.6 9.9 0.044 11.7 9.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_60s PF00428.19 CDJ53255.1 - 0.054 14.1 12.9 0.083 13.5 12.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein RXLR PF16810.5 CDJ53255.1 - 0.057 13.9 4.6 0.071 13.5 4.6 1.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Pex14_N PF04695.13 CDJ53255.1 - 0.073 13.7 21.9 0.095 13.4 21.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region R_equi_Vir PF05526.11 CDJ53255.1 - 0.095 12.6 8.4 0.12 12.2 8.4 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Peptidase_S49_N PF08496.10 CDJ53255.1 - 0.13 12.3 6.1 0.16 12.0 6.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RIC3 PF15361.6 CDJ53255.1 - 0.17 12.3 7.0 0.2 12.1 7.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Presenilin PF01080.17 CDJ53255.1 - 0.2 10.4 16.6 0.24 10.1 16.6 1.0 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 CDJ53255.1 - 0.22 9.9 1.7 0.21 10.0 1.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EOS1 PF12326.8 CDJ53255.1 - 0.23 11.4 3.5 0.27 11.1 3.5 1.3 1 0 0 1 1 1 0 N-glycosylation protein FAM60A PF15396.6 CDJ53255.1 - 0.26 11.2 7.6 0.3 11.1 7.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF1980 PF09323.10 CDJ53255.1 - 0.27 11.1 5.7 0.3 11.0 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4569 PF15133.6 CDJ53255.1 - 0.28 10.9 12.2 0.32 10.7 12.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) SelP_N PF04592.14 CDJ53255.1 - 0.35 10.2 27.9 0.42 10.0 27.9 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CSG2 PF16965.5 CDJ53255.1 - 0.42 9.5 2.8 0.41 9.6 2.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Endostatin PF06482.11 CDJ53255.1 - 0.42 10.0 12.8 0.46 9.9 12.8 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin BAF1_ABF1 PF04684.13 CDJ53255.1 - 0.45 9.5 18.5 0.55 9.2 18.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4228 PF14009.6 CDJ53255.1 - 0.45 10.9 7.7 0.56 10.6 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DDHD PF02862.17 CDJ53255.1 - 0.46 10.6 10.8 0.52 10.4 10.8 1.1 1 0 0 1 1 1 0 DDHD domain Velvet PF11754.8 CDJ53255.1 - 0.48 10.3 13.0 0.53 10.2 13.0 1.0 1 0 0 1 1 1 0 Velvet factor Baculo_PP31 PF05311.11 CDJ53255.1 - 0.48 9.9 10.0 0.54 9.7 10.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF4400 PF14348.6 CDJ53255.1 - 0.5 9.8 7.2 0.65 9.5 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Serinc PF03348.15 CDJ53255.1 - 0.56 9.1 4.4 0.57 9.1 4.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TCP PF03634.13 CDJ53255.1 - 0.59 10.7 14.0 0.7 10.4 14.0 1.1 1 0 0 1 1 1 0 TCP family transcription factor Macoilin PF09726.9 CDJ53255.1 - 0.69 8.4 12.9 0.93 8.0 12.9 1.2 1 0 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 CDJ53255.1 - 0.69 9.7 12.7 0.81 9.5 12.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ53255.1 - 0.74 8.7 15.0 0.82 8.6 15.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 CDJ53255.1 - 0.79 8.7 7.0 0.77 8.7 7.0 1.1 1 0 0 1 1 1 0 CLN3 protein DUF3984 PF13136.6 CDJ53255.1 - 0.84 9.0 15.8 0.96 8.8 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF3450 PF11932.8 CDJ53255.1 - 0.85 8.9 27.2 1.1 8.6 27.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Band_3_cyto PF07565.13 CDJ53255.1 - 0.86 9.3 12.6 0.99 9.2 12.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Hydin_ADK PF17213.3 CDJ53255.1 - 0.87 9.8 15.1 1.1 9.5 15.1 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Neur_chan_memb PF02932.16 CDJ53255.1 - 1 9.4 9.2 1.1 9.2 9.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CBP_BcsG PF11658.8 CDJ53255.1 - 1.1 7.6 10.0 1.2 7.5 10.0 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Gastrin PF00918.17 CDJ53255.1 - 1.3 10.0 11.2 1.7 9.6 11.2 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family SLC12 PF03522.15 CDJ53255.1 - 1.3 7.9 11.5 1.5 7.8 11.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 BORG_CEP PF14957.6 CDJ53255.1 - 1.3 10.1 7.0 1.6 9.9 7.0 1.1 1 0 0 1 1 1 0 Cdc42 effector Ctr PF04145.15 CDJ53255.1 - 2.1 8.9 5.7 2.6 8.7 5.7 1.2 1 0 0 1 1 1 0 Ctr copper transporter family PMSI1 PF15322.6 CDJ53255.1 - 2.5 7.5 11.3 3 7.2 11.3 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative NPR3 PF03666.13 CDJ53255.1 - 2.6 6.7 11.8 3.1 6.5 11.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cyt_bd_oxida_I PF01654.17 CDJ53255.1 - 3.1 6.3 6.9 3.4 6.2 6.9 1.0 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I DUF2828 PF11443.8 CDJ53255.1 - 3.2 5.7 13.5 3.6 5.6 13.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Tim54 PF11711.8 CDJ53255.1 - 3.2 6.4 11.8 3.7 6.2 11.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3138 PF11336.8 CDJ53255.1 - 3.8 6.0 13.1 4.2 5.9 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PAT1 PF09770.9 CDJ53255.1 - 3.8 5.6 26.5 4.4 5.5 26.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4050 PF13259.6 CDJ53255.1 - 4 7.7 11.7 4.9 7.4 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) TERB2 PF15101.6 CDJ53255.1 - 4.3 7.3 17.3 5.1 7.1 17.3 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EPL1 PF10513.9 CDJ53255.1 - 4.7 7.6 17.4 5.7 7.3 17.4 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Gti1_Pac2 PF09729.9 CDJ53255.1 - 4.8 7.2 11.5 5.5 7.0 11.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF3499 PF12005.8 CDJ53255.1 - 5 7.7 19.1 34 5.0 19.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3499) Sec62 PF03839.16 CDJ53255.1 - 5.3 6.5 10.2 6.4 6.2 10.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 MDM31_MDM32 PF08118.11 CDJ53255.1 - 6.1 5.4 8.9 7.3 5.1 8.9 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF5521 PF17659.1 CDJ53255.1 - 6.4 4.5 9.1 7.1 4.3 9.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Ureide_permease PF07168.11 CDJ53255.1 - 7.1 5.3 6.8 8.9 4.9 6.8 1.2 1 0 0 1 1 1 0 Ureide permease Rtf2 PF04641.12 CDJ53255.1 - 7.2 5.9 14.8 8.8 5.6 14.8 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger UPF0560 PF10577.9 CDJ53255.1 - 8 4.8 19.7 9 4.6 19.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PIP5K PF01504.18 CDJ53255.1 - 8.4 5.5 11.5 9.6 5.3 11.5 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase ALMT PF11744.8 CDJ53255.1 - 9.8 4.9 11.1 11 4.7 11.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter OATP PF03137.20 CDJ53255.1 - 9.9 4.3 6.6 11 4.2 6.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAM199X PF15814.5 CDJ53256.1 - 2 7.4 6.5 3.8 6.5 6.5 1.4 1 0 0 1 1 1 0 Protein family FAM199X Presenilin PF01080.17 CDJ53257.1 - 7.4e-05 21.7 24.2 7.4e-05 21.7 24.2 1.1 1 0 0 1 1 1 1 Presenilin Lin-8 PF03353.15 CDJ53257.1 - 0.0085 15.7 23.6 0.009 15.6 23.6 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist DUF3807 PF12720.7 CDJ53257.1 - 0.01 16.1 30.0 0.014 15.6 30.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Endostatin PF06482.11 CDJ53257.1 - 0.021 14.3 20.6 0.026 14.0 20.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Cellulose_synt PF03552.14 CDJ53257.1 - 0.023 13.2 3.9 0.023 13.2 3.9 1.1 1 0 0 1 1 1 0 Cellulose synthase AF-4 PF05110.13 CDJ53257.1 - 0.025 12.7 25.4 0.026 12.6 25.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Miga PF10265.9 CDJ53257.1 - 0.028 13.4 11.9 0.034 13.1 11.9 1.1 1 0 0 1 1 1 0 Mitoguardin PNISR PF15996.5 CDJ53257.1 - 0.032 14.5 28.1 0.043 14.1 28.1 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR LptF_LptG PF03739.14 CDJ53257.1 - 0.051 12.4 2.7 0.065 12.1 2.7 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG SAPS PF04499.15 CDJ53257.1 - 0.061 12.1 15.1 0.056 12.2 15.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM60A PF15396.6 CDJ53257.1 - 0.074 13.1 17.6 0.089 12.8 17.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Apt1 PF10351.9 CDJ53257.1 - 0.079 11.8 12.9 0.1 11.4 12.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SLC12 PF03522.15 CDJ53257.1 - 0.089 11.8 25.7 0.11 11.5 25.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PDDEXK_6 PF04720.12 CDJ53257.1 - 0.092 12.7 12.7 0.15 12.0 12.7 1.4 1 0 0 1 1 1 0 PDDEXK-like family of unknown function NARP1 PF12569.8 CDJ53257.1 - 0.1 11.5 23.2 0.11 11.3 23.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3295 PF11702.8 CDJ53257.1 - 0.11 11.8 20.4 0.11 11.8 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Pkinase_fungal PF17667.1 CDJ53257.1 - 0.12 11.1 9.0 0.13 11.0 9.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase CDC45 PF02724.14 CDJ53257.1 - 0.18 10.1 22.8 0.22 9.8 22.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 CDJ53257.1 - 0.21 11.6 18.7 0.25 11.4 18.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SRP-alpha_N PF04086.13 CDJ53257.1 - 0.24 11.3 23.1 0.27 11.1 23.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ALMT PF11744.8 CDJ53257.1 - 0.25 10.1 19.0 0.3 9.9 19.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_S64 PF08192.11 CDJ53257.1 - 0.29 9.6 19.5 0.32 9.4 19.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF913 PF06025.12 CDJ53257.1 - 0.32 9.9 15.1 0.38 9.7 15.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Dapper PF15268.6 CDJ53257.1 - 0.34 9.7 27.3 0.36 9.7 27.3 1.0 1 0 0 1 1 1 0 Dapper PAT1 PF09770.9 CDJ53257.1 - 0.35 9.1 46.0 0.4 8.9 46.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NPR3 PF03666.13 CDJ53257.1 - 0.39 9.5 24.8 0.48 9.2 24.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MMR1 PF08505.10 CDJ53257.1 - 0.4 10.9 27.5 0.56 10.5 27.5 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PIG-S PF10510.9 CDJ53257.1 - 0.41 9.4 15.8 0.51 9.1 15.8 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF966 PF06136.13 CDJ53257.1 - 0.48 10.1 16.5 0.54 9.9 16.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDK5_activator PF03261.15 CDJ53257.1 - 0.49 9.9 16.7 0.52 9.8 16.7 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF2151 PF10221.9 CDJ53257.1 - 0.5 8.9 13.3 0.59 8.7 13.3 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Velvet PF11754.8 CDJ53257.1 - 0.58 10.0 22.2 0.78 9.6 22.2 1.3 1 0 0 1 1 1 0 Velvet factor DUF4569 PF15133.6 CDJ53257.1 - 0.59 9.8 23.5 0.8 9.4 23.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Draxin PF15550.6 CDJ53257.1 - 0.6 9.9 21.2 0.69 9.7 21.2 1.0 1 0 0 1 1 1 0 Draxin DUF4045 PF13254.6 CDJ53257.1 - 0.63 9.6 27.8 0.7 9.5 27.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PA26 PF04636.13 CDJ53257.1 - 0.77 8.6 18.2 0.92 8.4 18.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SID-1_RNA_chan PF13965.6 CDJ53257.1 - 0.79 8.1 11.3 0.96 7.8 11.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BORG_CEP PF14957.6 CDJ53257.1 - 0.84 10.8 16.6 1.1 10.4 16.6 1.3 1 0 0 1 1 1 0 Cdc42 effector AUX_IAA PF02309.16 CDJ53257.1 - 0.9 9.3 16.0 1 9.2 16.0 1.4 1 0 0 1 1 1 0 AUX/IAA family Macoilin PF09726.9 CDJ53257.1 - 0.95 7.9 21.2 1.2 7.6 21.2 1.2 1 0 0 1 1 1 0 Macoilin family CCSAP PF15748.5 CDJ53257.1 - 1 9.5 34.2 1.3 9.1 34.2 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF1387 PF07139.11 CDJ53257.1 - 1.1 9.0 25.2 1.3 8.7 25.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) VIR_N PF15912.5 CDJ53257.1 - 1.2 8.6 15.0 1.7 8.2 15.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal LMBR1 PF04791.16 CDJ53257.1 - 1.3 7.8 10.7 1.5 7.7 10.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2126 PF09899.9 CDJ53257.1 - 1.3 7.0 17.7 1.6 6.7 17.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RR_TM4-6 PF06459.12 CDJ53257.1 - 1.3 8.7 30.8 1.7 8.4 30.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4638 PF15472.6 CDJ53257.1 - 1.3 8.6 23.4 1.7 8.3 23.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF4050 PF13259.6 CDJ53257.1 - 1.4 9.2 21.1 1.9 8.8 21.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Membralin PF09746.9 CDJ53257.1 - 1.7 7.6 16.4 2.1 7.3 16.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein Hid1 PF12722.7 CDJ53257.1 - 1.8 6.6 24.9 2.1 6.4 24.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2052 PF09747.9 CDJ53257.1 - 1.9 8.6 29.3 2.5 8.2 29.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) MDM10 PF12519.8 CDJ53257.1 - 2 7.2 22.5 2.4 6.9 22.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Dsh_C PF12316.8 CDJ53257.1 - 2 8.7 19.2 2.6 8.4 19.2 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF572 PF04502.13 CDJ53257.1 - 2.4 7.7 25.6 2.7 7.6 25.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) LAP1C PF05609.12 CDJ53257.1 - 2.6 7.1 28.3 3 6.8 28.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Mcm10 PF09332.11 CDJ53257.1 - 2.6 7.4 30.7 3.1 7.1 30.7 1.1 1 0 0 1 1 1 0 Mcm10 replication factor GAGA_bind PF06217.12 CDJ53257.1 - 2.8 8.1 22.5 3.1 8.0 22.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Band_3_cyto PF07565.13 CDJ53257.1 - 2.8 7.7 23.2 4.6 7.0 23.2 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4746 PF15928.5 CDJ53257.1 - 3 7.2 20.8 4 6.8 20.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SWI-SNF_Ssr4 PF08549.10 CDJ53257.1 - 3.1 6.3 30.2 3.4 6.2 30.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SOG2 PF10428.9 CDJ53257.1 - 3.2 6.9 21.4 3.6 6.7 21.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PE_PPE_C PF12484.8 CDJ53257.1 - 3.2 8.7 31.8 8.9 7.3 13.6 2.3 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal Raftlin PF15250.6 CDJ53257.1 - 3.5 6.3 22.9 4.2 6.0 22.9 1.1 1 0 0 1 1 1 0 Raftlin DUF4551 PF15087.6 CDJ53257.1 - 3.5 6.3 20.4 4.3 6.0 20.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GREB1 PF15782.5 CDJ53257.1 - 3.8 4.5 30.7 3.9 4.5 30.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 CDJ53257.1 - 4.1 5.9 23.7 4.4 5.8 23.7 1.0 1 0 0 1 1 1 0 Hamartin protein DUF3292 PF11696.8 CDJ53257.1 - 4.7 5.5 20.1 7 4.9 20.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Paramyxo_ncap PF00973.19 CDJ53257.1 - 5.5 5.8 21.6 6.5 5.5 21.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein VIT1 PF01988.19 CDJ53257.1 - 6.5 6.6 25.2 13 5.6 25.2 1.5 1 1 0 1 1 1 0 VIT family ASC PF00858.24 CDJ53257.1 - 6.9 5.5 14.3 8.3 5.3 14.3 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel PPL5 PF18168.1 CDJ53257.1 - 7.1 5.8 20.2 10 5.3 20.2 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Plasmodium_Vir PF05795.11 CDJ53257.1 - 7.1 5.9 14.7 9.4 5.5 14.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GPCR_chapero_1 PF11904.8 CDJ53257.1 - 7.8 5.8 18.4 8.9 5.6 18.4 1.1 1 0 0 1 1 1 0 GPCR-chaperone F-protein PF00469.20 CDJ53257.1 - 10 5.7 20.4 16 5.0 20.4 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef SpoU_methylase PF00588.19 CDJ53258.1 - 4.9e-13 49.5 0.4 2.8e-12 47.0 0.0 2.5 2 0 0 2 2 2 1 SpoU rRNA Methylase family Kinesin PF00225.23 CDJ53258.1 - 7.4e-10 38.3 1.8 5e-09 35.5 2.9 7.6 5 3 3 8 8 8 3 Kinesin motor domain SPX PF03105.19 CDJ53258.1 - 0.0001 22.4 11.4 0.0001 22.4 11.4 6.1 5 1 1 6 6 6 3 SPX domain BUD22 PF09073.10 CDJ53258.1 - 0.0006 19.3 0.9 0.0006 19.3 0.9 6.1 4 3 1 5 5 5 1 BUD22 AAA_23 PF13476.6 CDJ53258.1 - 0.0058 17.2 0.5 0.0058 17.2 0.5 4.6 4 0 0 4 4 4 1 AAA domain MMR1 PF08505.10 CDJ53258.1 - 0.0082 16.5 5.0 0.0082 16.5 5.0 6.7 5 2 1 6 6 6 1 Mitochondrial Myo2 receptor-related protein Pex14_N PF04695.13 CDJ53258.1 - 0.012 16.2 13.3 0.012 16.2 13.3 9.7 8 2 0 8 8 8 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4484 PF14831.6 CDJ53258.1 - 0.017 15.2 0.9 0.017 15.2 0.9 6.0 5 1 0 5 5 5 0 Domain of unknown function (DUF4484) Band_3_cyto PF07565.13 CDJ53258.1 - 0.037 13.8 0.2 0.037 13.8 0.2 6.1 5 1 1 6 6 6 0 Band 3 cytoplasmic domain LMBR1 PF04791.16 CDJ53258.1 - 0.042 12.7 0.0 0.042 12.7 0.0 3.6 4 0 0 4 4 4 0 LMBR1-like membrane protein DUF1772 PF08592.11 CDJ53259.1 - 0.072 13.4 0.1 0.072 13.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Parvo_coat PF00740.18 CDJ53260.1 - 0.015 14.0 5.5 0.016 13.9 5.5 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Plasmodium_Vir PF05795.11 CDJ53260.1 - 0.019 14.4 1.7 0.029 13.8 1.4 1.3 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Zip PF02535.22 CDJ53260.1 - 0.063 12.5 5.7 0.12 11.6 5.7 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.5 CDJ53260.1 - 0.18 8.9 13.2 0.19 8.8 13.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 CDJ53260.1 - 0.51 9.1 10.5 0.65 8.8 10.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SMYLE_N PF18615.1 CDJ53260.1 - 0.7 9.4 11.6 0.9 9.0 11.6 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Neur_chan_memb PF02932.16 CDJ53260.1 - 1.2 9.1 13.3 1.9 8.5 13.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 CDJ53260.1 - 1.9 6.7 34.3 2.3 6.4 34.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4667 PF15700.5 CDJ53260.1 - 3.8 7.6 12.8 0.072 13.2 6.3 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4667) Exonuc_VII_L PF02601.15 CDJ53260.1 - 4 6.9 22.6 6.2 6.3 22.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SLC12 PF03522.15 CDJ53260.1 - 7.3 5.5 15.9 9.9 5.1 15.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Vfa1 PF08432.10 CDJ53260.1 - 9.5 6.5 21.9 14 6.0 21.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NAM-associated PF14303.6 CDJ53261.1 - 1.7e-07 32.1 0.0 1.7e-07 32.1 0.0 9.7 3 2 2 5 5 5 1 No apical meristem-associated C-terminal domain AF-4 PF05110.13 CDJ53261.1 - 0.00031 19.0 61.1 0.00031 19.0 61.1 6.4 5 2 0 6 6 6 1 AF-4 proto-oncoprotein TCP PF03634.13 CDJ53261.1 - 0.00057 20.5 13.8 0.00057 20.5 13.8 6.9 4 2 1 6 6 6 1 TCP family transcription factor BUD22 PF09073.10 CDJ53261.1 - 0.0048 16.3 10.0 0.0048 16.3 10.0 6.8 4 1 1 5 5 5 2 BUD22 EMC3_TMCO1 PF01956.16 CDJ53262.1 - 0.57 9.9 1.6 0.77 9.5 1.6 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MCM_bind PF09739.9 CDJ53262.1 - 1.5 7.1 7.3 2.2 6.6 7.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor UPF0560 PF10577.9 CDJ53262.1 - 4.1 5.8 13.2 6.3 5.2 13.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Utp14 PF04615.13 CDJ53262.1 - 5.2 5.5 21.5 6.7 5.1 21.5 1.2 1 0 0 1 1 1 0 Utp14 protein Connexin PF00029.19 CDJ53262.1 - 7 6.3 5.3 11 5.7 5.3 1.2 1 0 0 1 1 1 0 Connexin COX6A PF02046.15 CDJ53262.1 - 9.9 6.7 8.1 1.3 9.5 2.6 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIa SPX PF03105.19 CDJ53263.1 - 2.6e-05 24.4 2.5 2.6e-05 24.4 2.5 4.1 3 1 1 4 4 4 1 SPX domain DUF3833 PF12915.7 CDJ53263.1 - 0.011 15.4 1.6 0.024 14.2 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3833) MTABC_N PF16185.5 CDJ53264.1 - 0.38 10.2 3.0 0.49 9.9 3.0 1.1 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region DUF4834 PF16118.5 CDJ53264.1 - 0.4 11.7 9.5 1.1 10.3 9.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ53264.1 - 0.58 10.1 25.6 0.66 9.9 25.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ53264.1 - 0.7 8.8 9.5 0.75 8.7 9.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ53264.1 - 1.6 6.6 6.9 1.6 6.5 6.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_60s PF00428.19 CDJ53264.1 - 2.2 8.9 15.1 13 6.4 16.6 1.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Presenilin PF01080.17 CDJ53264.1 - 2.4 6.9 6.8 2.5 6.8 6.8 1.1 1 0 0 1 1 1 0 Presenilin IF-2 PF11987.8 CDJ53265.1 - 7e-05 22.9 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 AF-4 PF05110.13 CDJ53265.1 - 0.011 13.8 34.5 0.014 13.5 34.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TFIIA PF03153.13 CDJ53265.1 - 0.024 14.6 66.4 0.0049 16.9 62.6 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit X PF00739.19 CDJ53265.1 - 1.9 8.6 4.1 23 5.1 0.0 2.6 2 0 0 2 2 2 0 Trans-activation protein X Abhydrolase_2 PF02230.16 CDJ53266.1 - 1.7e-33 116.2 0.0 5.1e-27 95.1 0.0 3.0 1 1 2 3 3 3 3 Phospholipase/Carboxylesterase FSH1 PF03959.13 CDJ53266.1 - 4.2e-09 36.4 0.3 6.5e-08 32.5 0.1 2.6 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 CDJ53266.1 - 1e-05 25.0 0.5 0.18 11.1 0.1 3.5 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CDJ53266.1 - 2.6e-05 23.8 0.4 0.0018 17.8 0.5 3.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ53266.1 - 0.00011 22.0 0.4 0.34 10.5 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ53266.1 - 0.00011 22.9 0.0 0.00018 22.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDJ53266.1 - 0.0013 18.6 0.5 0.0027 17.6 0.5 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 CDJ53266.1 - 0.014 15.0 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 CDJ53266.1 - 0.028 14.0 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF72 PF01904.18 CDJ53266.1 - 0.035 14.2 0.4 3.3 7.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF72 Ribosomal_60s PF00428.19 CDJ53266.1 - 0.94 10.1 10.6 1.9 9.2 10.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.25 CDJ53267.1 - 1.8e-45 155.4 9.5 5.9e-38 130.7 0.0 3.3 2 1 1 3 3 2 2 Protein kinase domain EF-hand_1 PF00036.32 CDJ53267.1 - 6.9e-28 94.1 6.9 1.1e-07 30.9 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CDJ53267.1 - 6.1e-25 85.6 6.1 3.2e-08 32.7 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDJ53267.1 - 8.6e-24 81.4 2.3 1.6e-06 27.6 0.0 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CDJ53267.1 - 2.9e-23 82.1 1.9 2.2e-12 47.3 1.6 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ53267.1 - 2.2e-19 69.0 11.6 1.1e-07 31.6 3.5 3.9 2 2 2 4 4 4 3 EF-hand domain pair Pkinase_Tyr PF07714.17 CDJ53267.1 - 2e-17 63.3 0.0 2e-17 63.3 0.0 3.2 3 1 1 4 4 3 1 Protein tyrosine kinase EF-hand_9 PF14658.6 CDJ53267.1 - 7.1e-06 26.3 0.3 0.0066 16.8 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDJ53267.1 - 0.013 15.4 13.1 0.027 14.4 0.5 3.8 2 1 1 3 3 2 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ53267.1 - 0.026 14.8 0.0 0.49 10.7 0.0 3.9 2 2 2 4 4 3 0 Secreted protein acidic and rich in cysteine Ca binding region Ndc1_Nup PF09531.10 CDJ53267.1 - 0.12 11.0 11.0 0.15 10.7 11.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VCBS PF13517.6 CDJ53267.1 - 0.54 10.9 2.8 16 6.2 0.5 3.0 3 1 0 3 3 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Dockerin_1 PF00404.18 CDJ53267.1 - 0.77 10.0 4.4 14 5.9 0.7 3.6 1 1 3 4 4 4 0 Dockerin type I domain TFIIA PF03153.13 CDJ53267.1 - 1.3 8.9 50.2 2.4 8.1 50.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Caleosin PF05042.13 CDJ53267.1 - 2.6 7.9 5.8 5.1 7.0 0.0 3.3 3 1 1 4 4 3 0 Caleosin related protein FAM222A PF15258.6 CDJ53267.1 - 8.4 5.4 39.5 13 4.8 39.5 1.2 1 0 0 1 1 1 0 Protein family of FAM222A DUF4164 PF13747.6 CDJ53268.1 - 0.0093 16.2 3.5 0.0093 16.2 3.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4164) AraC_N PF06719.13 CDJ53268.1 - 0.033 13.8 6.5 0.042 13.5 6.5 1.1 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus V_ATPase_I PF01496.19 CDJ53268.1 - 1.2 6.9 13.6 1.3 6.9 13.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dicty_REP PF05086.12 CDJ53268.1 - 3.3 5.6 7.7 4 5.3 7.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pterin_bind PF00809.22 CDJ53269.1 - 3.4e-50 171.0 0.4 6.1e-50 170.2 0.4 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 CDJ53269.1 - 2.1e-12 47.5 0.2 3.4e-11 43.7 0.0 2.8 3 1 0 3 3 3 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Tic110 PF16940.5 CDJ53269.1 - 0.12 10.9 8.8 0.2 10.1 8.8 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter Med3 PF11593.8 CDJ53269.1 - 0.26 10.4 5.9 0.45 9.6 5.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal tRNA-synt_1 PF00133.22 CDJ53270.1 - 1.8e-17 62.8 0.0 2.2e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDJ53270.1 - 2.5e-07 29.8 0.0 8e-07 28.1 0.0 1.8 2 1 1 3 3 3 1 tRNA synthetases class I (M) RNase_H2_suC PF08615.11 CDJ53270.1 - 0.011 15.9 0.3 0.89 9.7 0.3 2.2 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Spt20 PF12090.8 CDJ53270.1 - 0.18 11.4 5.7 0.27 10.8 3.3 2.1 2 1 0 2 2 2 0 Spt20 family DUF3947 PF13135.6 CDJ53270.1 - 0.2 11.9 6.1 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) BAF1_ABF1 PF04684.13 CDJ53271.1 - 0.046 12.8 31.3 0.054 12.5 31.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ53271.1 - 5.1 5.7 43.8 6.5 5.4 43.8 1.2 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 CDJ53271.1 - 7 6.2 34.0 7.8 6.0 34.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) MAP7 PF05672.11 CDJ53271.1 - 7.1 6.3 63.6 9.9 5.8 63.6 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family SelP_N PF04592.14 CDJ53272.1 - 1 8.7 40.0 1.3 8.4 40.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Band_3_cyto PF07565.13 CDJ53272.1 - 4.4 7.0 29.2 5.6 6.7 29.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM76 PF16046.5 CDJ53272.1 - 6.4 6.0 31.9 8.8 5.6 31.9 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4746 PF15928.5 CDJ53272.1 - 7.4 5.9 23.0 9.3 5.6 23.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 CDJ53272.1 - 7.8 4.7 26.5 8.8 4.5 26.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ53272.1 - 8.3 5.0 38.1 9.9 4.8 38.1 1.0 1 0 0 1 1 1 0 Presenilin Anticodon_1 PF08264.13 CDJ53273.1 - 1.7e-13 50.8 0.5 3.1e-13 49.9 0.5 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA SARAF PF06682.12 CDJ53273.1 - 1.3e-07 31.6 9.2 1.3e-07 31.6 9.2 2.0 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis SpoIIIAH PF12685.7 CDJ53273.1 - 4.2e-05 23.5 8.9 0.0001 22.2 6.5 2.2 2 0 0 2 2 2 1 SpoIIIAH-like protein TMEM154 PF15102.6 CDJ53273.1 - 7.6e-05 22.6 1.3 7.6e-05 22.6 1.3 2.4 2 1 1 3 3 1 1 TMEM154 protein family EphA2_TM PF14575.6 CDJ53273.1 - 0.00015 22.5 0.9 0.00015 22.5 0.9 3.3 3 0 0 3 3 2 1 Ephrin type-A receptor 2 transmembrane domain SID-1_RNA_chan PF13965.6 CDJ53273.1 - 0.00063 18.3 3.0 0.00063 18.3 3.0 1.5 2 0 0 2 2 2 1 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 CDJ53273.1 - 0.0015 16.6 17.8 0.0015 16.6 17.8 1.9 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family Baculo_11_kDa PF06143.11 CDJ53273.1 - 0.0045 16.5 3.9 0.0045 16.5 3.9 3.0 3 1 0 3 3 1 1 Baculovirus 11 kDa family CLN3 PF02487.17 CDJ53273.1 - 0.0047 16.0 10.7 0.0047 16.0 10.7 1.9 2 0 0 2 2 2 1 CLN3 protein Peptidase_S49_N PF08496.10 CDJ53273.1 - 0.0059 16.7 13.0 0.0059 16.7 13.0 2.6 3 0 0 3 3 2 1 Peptidase family S49 N-terminal O-antigen_lig PF13425.6 CDJ53273.1 - 0.0067 15.3 3.5 0.0067 15.3 3.5 1.6 2 0 0 2 2 2 1 O-antigen ligase like membrane protein Neur_chan_memb PF02932.16 CDJ53273.1 - 0.0081 16.2 12.6 0.013 15.6 9.1 2.2 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Ctr PF04145.15 CDJ53273.1 - 0.0083 16.8 10.7 0.023 15.3 6.2 2.5 2 0 0 2 2 2 1 Ctr copper transporter family GRP PF07172.11 CDJ53273.1 - 0.0089 16.7 1.1 0.0089 16.7 1.1 2.6 3 0 0 3 3 1 1 Glycine rich protein family Pex24p PF06398.11 CDJ53273.1 - 0.0095 15.0 0.1 0.13 11.2 0.0 2.1 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Connexin PF00029.19 CDJ53273.1 - 0.01 15.6 8.9 0.01 15.6 8.9 2.2 2 0 0 2 2 2 0 Connexin Conotoxin PF02950.17 CDJ53273.1 - 0.011 16.7 5.6 0.011 16.7 5.6 3.3 2 1 1 3 3 2 0 Conotoxin Ac76 PF05814.11 CDJ53273.1 - 0.014 15.4 1.5 0.044 13.8 1.5 1.8 1 0 0 1 1 1 0 Orf76 (Ac76) DUF3357 PF11837.8 CDJ53273.1 - 0.017 15.6 0.9 0.017 15.6 0.9 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF3357) CCDC53 PF10152.9 CDJ53273.1 - 0.017 15.5 12.7 0.017 15.5 12.7 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF5385 PF17359.2 CDJ53273.1 - 0.022 14.4 0.6 0.022 14.4 0.6 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5385) SIT PF15330.6 CDJ53273.1 - 0.022 15.2 21.1 0.022 15.2 21.1 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4307 PF14155.6 CDJ53273.1 - 0.023 14.5 0.3 0.061 13.2 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) TssO PF17561.2 CDJ53273.1 - 0.028 14.5 1.4 0.028 14.5 1.4 3.1 3 0 0 3 3 2 0 Type VI secretion system, TssO DUF3169 PF11368.8 CDJ53273.1 - 0.032 13.8 0.2 0.032 13.8 0.2 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3169) Tetraspanin PF00335.20 CDJ53273.1 - 0.043 13.5 1.7 0.091 12.5 1.7 1.6 1 0 0 1 1 1 0 Tetraspanin family HemY_N PF07219.13 CDJ53273.1 - 0.055 13.7 0.6 0.055 13.7 0.6 3.3 4 0 0 4 4 2 0 HemY protein N-terminus TMEM132D_C PF15706.5 CDJ53273.1 - 0.059 13.1 0.1 0.059 13.1 0.1 3.2 3 0 0 3 3 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SecY PF00344.20 CDJ53273.1 - 0.11 11.8 0.2 0.21 10.8 0.2 1.4 1 0 0 1 1 1 0 SecY translocase Cytochrom_B_N_2 PF13631.6 CDJ53273.1 - 0.13 12.2 0.1 0.13 12.2 0.1 1.9 2 0 0 2 2 1 0 Cytochrome b(N-terminal)/b6/petB Serinc PF03348.15 CDJ53273.1 - 0.16 10.9 9.4 0.0081 15.1 4.0 1.6 2 0 0 2 2 2 0 Serine incorporator (Serinc) Choline_transpo PF04515.12 CDJ53273.1 - 0.17 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Plasma-membrane choline transporter Ni_hydr_CYTB PF01292.20 CDJ53273.1 - 0.19 11.3 0.2 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Zip PF02535.22 CDJ53273.1 - 0.21 10.8 4.8 0.059 12.6 1.7 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter MFS_1_like PF12832.7 CDJ53273.1 - 0.21 10.4 0.5 1.1 8.0 0.2 2.0 2 0 0 2 2 2 0 MFS_1 like family AUX_IAA PF02309.16 CDJ53273.1 - 0.33 10.8 12.1 0.88 9.4 12.2 1.7 1 1 0 1 1 1 0 AUX/IAA family Sulf_transp PF04143.14 CDJ53273.1 - 0.37 10.3 1.5 0.44 10.1 0.3 1.7 2 0 0 2 2 2 0 Sulphur transport Baculo_PP31 PF05311.11 CDJ53273.1 - 0.46 9.9 13.0 0.71 9.3 8.7 2.3 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) OATP PF03137.20 CDJ53273.1 - 0.63 8.3 8.1 0.06 11.6 3.1 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TRAP_alpha PF03896.16 CDJ53273.1 - 0.73 9.0 10.8 0.07 12.3 6.3 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit BORG_CEP PF14957.6 CDJ53273.1 - 0.92 10.7 10.1 1.4 10.0 7.1 2.3 2 0 0 2 2 2 0 Cdc42 effector DUF4330 PF14221.6 CDJ53273.1 - 0.98 9.6 8.0 0.15 12.2 2.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) DUF1180 PF06679.12 CDJ53273.1 - 1.2 9.5 11.6 0.16 12.4 7.1 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1180) DUF1980 PF09323.10 CDJ53273.1 - 1.3 8.9 13.6 0.56 10.1 6.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4484 PF14831.6 CDJ53273.1 - 1.5 8.8 15.3 20 5.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) CBP_BcsG PF11658.8 CDJ53273.1 - 1.8 6.9 19.4 0.071 11.5 12.8 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG DUF2828 PF11443.8 CDJ53273.1 - 3.2 5.7 19.0 0.78 7.8 14.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Mit_KHE1 PF10173.9 CDJ53273.1 - 4.5 7.3 17.1 0.72 9.9 7.1 2.9 3 0 0 3 3 3 0 Mitochondrial K+-H+ exchange-related DUF4834 PF16118.5 CDJ53273.1 - 6.8 7.7 42.9 17 6.5 0.6 3.3 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) CSG2 PF16965.5 CDJ53273.1 - 8.8 5.2 11.7 2 7.3 7.9 1.8 2 0 0 2 2 2 0 Ceramide synthase regulator FAM176 PF14851.6 CDJ53273.1 - 9.9 5.8 22.7 46 3.7 0.1 3.1 2 1 0 2 2 2 0 FAM176 family SUIM_assoc PF16619.5 CDJ53274.1 - 0.00063 19.8 6.6 0.00063 19.8 6.6 6.6 3 2 1 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 FKBP_C PF00254.28 CDJ53274.1 - 0.00068 19.9 2.3 0.0015 18.8 0.1 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2076 PF09849.9 CDJ53274.1 - 0.002 18.2 35.1 0.002 18.2 35.1 3.2 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2076) DUF572 PF04502.13 CDJ53274.1 - 0.0023 17.6 18.3 0.0023 17.6 18.3 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF572) Otopetrin PF03189.13 CDJ53274.1 - 0.003 16.5 0.6 0.014 14.2 0.6 2.1 1 1 0 1 1 1 1 Otopetrin N6_N4_Mtase PF01555.18 CDJ53274.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.9 1 1 0 1 1 1 0 DNA methylase TAF4 PF05236.14 CDJ53275.1 - 0.0086 15.9 15.3 0.013 15.3 15.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF4770 PF15994.5 CDJ53275.1 - 0.083 13.1 25.4 0.45 10.7 7.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Sin_N PF04801.13 CDJ53275.1 - 0.089 12.0 36.6 0.12 11.6 36.6 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region BAF1_ABF1 PF04684.13 CDJ53275.1 - 0.11 11.6 17.1 0.13 11.3 17.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDC27 PF09507.10 CDJ53275.1 - 0.18 11.2 23.3 0.19 11.1 23.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF908 PF06012.12 CDJ53275.1 - 0.2 11.0 18.5 0.23 10.8 18.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Presenilin PF01080.17 CDJ53275.1 - 0.23 10.2 26.6 0.26 10.0 26.6 1.1 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 CDJ53275.1 - 0.68 8.2 14.6 0.81 8.0 14.6 1.0 1 0 0 1 1 1 0 Menin NPR3 PF03666.13 CDJ53275.1 - 0.75 8.5 15.6 0.99 8.1 15.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AF-4 PF05110.13 CDJ53275.1 - 1.1 7.3 29.9 1.3 7.1 29.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FAM60A PF15396.6 CDJ53275.1 - 1.3 9.0 19.1 1.7 8.6 19.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SAPS PF04499.15 CDJ53275.1 - 1.6 7.5 16.6 1.7 7.3 16.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 CDJ53275.1 - 2.1 6.6 16.0 2.4 6.3 16.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.6 CDJ53275.1 - 2.2 7.0 17.6 2.6 6.7 17.6 1.1 1 0 0 1 1 1 0 Raftlin ALMT PF11744.8 CDJ53275.1 - 2.3 6.9 15.5 2.8 6.6 15.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter AUX_IAA PF02309.16 CDJ53275.1 - 2.3 8.0 13.7 2.9 7.7 13.7 1.3 1 0 0 1 1 1 0 AUX/IAA family FAM150 PF15129.6 CDJ53275.1 - 3.3 7.9 22.2 0.26 11.4 7.4 2.2 2 0 0 2 2 2 0 FAM150 family SWI-SNF_Ssr4 PF08549.10 CDJ53275.1 - 3.3 6.2 26.9 3.8 6.0 26.9 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SMYLE_N PF18615.1 CDJ53275.1 - 3.3 7.2 14.9 4.3 6.8 14.9 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Smg8_Smg9 PF10220.9 CDJ53275.1 - 3.8 5.7 20.6 4.3 5.5 20.6 1.0 1 0 0 1 1 1 0 Smg8_Smg9 SLC12 PF03522.15 CDJ53275.1 - 4.4 6.2 23.8 5.6 5.9 23.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF966 PF06136.13 CDJ53275.1 - 4.5 6.9 18.2 5.4 6.6 18.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4647 PF15504.6 CDJ53275.1 - 4.8 6.2 23.7 5.7 5.9 23.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) VIR_N PF15912.5 CDJ53275.1 - 6 6.4 16.4 7.8 6.0 16.4 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Thg1C PF14413.6 CDJ53275.1 - 6.4 7.0 17.7 2.8 8.1 3.1 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain PBP1_TM PF14812.6 CDJ53275.1 - 7.9 6.9 12.4 4.8 7.6 5.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal THOC2_N PF16134.5 CDJ53275.1 - 8.1 4.9 17.2 12 4.4 17.2 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Hamartin PF04388.12 CDJ53275.1 - 9 4.8 22.5 10 4.6 22.5 1.0 1 0 0 1 1 1 0 Hamartin protein Rtf2 PF04641.12 CDJ53275.1 - 9.3 5.5 20.2 13 5.1 20.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Pkinase PF00069.25 CDJ53276.1 - 3.7e-18 65.8 2.2 6.5e-14 51.9 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ53276.1 - 5.7e-11 42.2 0.1 5.7e-11 42.2 0.1 2.5 2 2 1 3 3 3 1 Protein tyrosine kinase RskA PF10099.9 CDJ53276.1 - 0.0003 21.1 1.1 0.0003 21.1 1.1 7.3 1 1 4 6 6 6 1 Anti-sigma-K factor rskA RskA PF10099.9 CDJ53277.1 - 0.0021 18.4 13.2 0.0021 18.4 13.2 4.3 1 1 1 3 3 3 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ53277.1 - 2.1 9.0 9.8 4.4 8.0 9.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pox_Ag35 PF03286.14 CDJ53277.1 - 6.5 6.5 23.2 5.4 6.8 13.2 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein AF-4 PF05110.13 CDJ53278.1 - 0.00083 17.6 26.9 0.0014 16.8 26.9 1.4 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Peptidase_S64 PF08192.11 CDJ53278.1 - 0.29 9.6 17.5 0.51 8.8 17.5 1.4 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_M56 PF05569.11 CDJ53278.1 - 2.4 7.3 5.0 0.68 9.1 1.3 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 Duffy_binding PF05424.11 CDJ53279.1 - 0.041 13.9 1.0 0.058 13.4 0.1 1.6 2 0 0 2 2 2 0 Duffy binding domain DUF4667 PF15700.5 CDJ53279.1 - 1.4 9.0 8.3 0.79 9.8 3.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ53279.1 - 2.7 7.5 9.5 7.3 6.1 9.5 1.7 1 0 0 1 1 1 0 Spt20 family Collagen PF01391.18 CDJ53280.1 - 0.00032 20.4 8.9 0.00032 20.4 8.9 2.7 4 0 0 4 4 4 1 Collagen triple helix repeat (20 copies) DUF929 PF06053.11 CDJ53280.1 - 0.53 9.6 3.1 0.75 9.1 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF4551 PF15087.6 CDJ53281.1 - 8.4 5.1 39.7 11 4.8 39.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Connexin PF00029.19 CDJ53282.1 - 0.00019 21.3 4.5 0.0022 17.8 2.9 2.4 2 0 0 2 2 2 1 Connexin Pox_Ag35 PF03286.14 CDJ53282.1 - 0.0042 16.9 4.2 0.0042 16.9 4.2 1.8 2 0 0 2 2 2 1 Pox virus Ag35 surface protein DUF913 PF06025.12 CDJ53282.1 - 0.0043 16.1 6.1 0.0097 14.9 3.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF2722 PF10846.8 CDJ53282.1 - 0.0044 16.0 3.4 0.0044 16.0 3.4 4.5 3 1 2 5 5 1 1 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ53282.1 - 0.025 13.4 20.6 0.84 8.3 17.0 2.5 2 0 0 2 2 2 0 Presenilin FAM176 PF14851.6 CDJ53282.1 - 0.035 13.8 15.0 0.029 14.0 10.7 2.4 2 0 0 2 2 2 0 FAM176 family SARAF PF06682.12 CDJ53282.1 - 0.056 13.1 17.8 0.97 9.0 1.1 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Serinc PF03348.15 CDJ53282.1 - 0.2 10.5 8.9 0.05 12.5 4.6 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) Cwf_Cwc_15 PF04889.12 CDJ53282.1 - 0.28 10.9 20.9 0.72 9.5 16.7 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF1980 PF09323.10 CDJ53282.1 - 0.34 10.8 12.8 0.13 12.2 5.6 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF1980) DUF4050 PF13259.6 CDJ53282.1 - 0.43 10.9 17.5 8.6 6.6 12.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) PIP5K PF01504.18 CDJ53282.1 - 0.5 9.5 12.2 3.6 6.7 10.1 2.3 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase PPL5 PF18168.1 CDJ53282.1 - 0.5 9.6 12.0 0.26 10.5 7.5 2.3 2 0 0 2 2 2 0 Prim-pol family 5 Caldesmon PF02029.15 CDJ53282.1 - 0.54 9.0 21.5 0.0046 15.8 9.6 2.5 3 0 0 3 3 3 0 Caldesmon MecA PF05389.12 CDJ53282.1 - 0.68 9.5 14.1 4.9 6.7 10.7 2.7 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) FAM60A PF15396.6 CDJ53282.1 - 0.73 9.8 15.0 2.7 7.9 12.8 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Paf1 PF03985.13 CDJ53282.1 - 0.9 8.5 25.2 5.1 6.0 21.6 2.2 2 0 0 2 2 2 0 Paf1 eIF-3_zeta PF05091.12 CDJ53282.1 - 0.9 8.4 26.6 5.1 6.0 0.3 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ53282.1 - 0.9 9.5 21.0 0.47 10.5 10.1 3.3 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 CDJ53282.1 - 1.2 7.4 8.3 0.34 9.3 5.1 1.6 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF5523 PF17661.1 CDJ53282.1 - 2.4 7.8 23.1 0.29 10.8 14.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Gti1_Pac2 PF09729.9 CDJ53282.1 - 2.5 8.2 18.3 15 5.6 14.6 2.6 2 0 0 2 2 2 0 Gti1/Pac2 family Hid1 PF12722.7 CDJ53282.1 - 2.7 6.0 15.5 0.33 9.0 8.7 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 CDJ53282.1 - 2.9 6.6 14.3 1.5 7.5 10.4 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein OATP PF03137.20 CDJ53282.1 - 3.3 5.9 7.1 1 7.6 3.0 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TFB6 PF17110.5 CDJ53282.1 - 3.4 7.4 11.8 8.7 6.1 8.7 2.8 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH RR_TM4-6 PF06459.12 CDJ53282.1 - 3.6 7.3 25.5 1.5 8.6 17.2 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 CDJ53282.1 - 4.5 6.0 17.2 3.1 6.5 10.5 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.13 CDJ53282.1 - 4.8 5.9 22.3 0.023 13.5 8.1 2.9 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 GPCR_chapero_1 PF11904.8 CDJ53282.1 - 5.3 6.4 12.8 7.3 5.9 10.5 2.1 2 0 0 2 2 2 0 GPCR-chaperone SpoIIP PF07454.11 CDJ53282.1 - 7 6.0 21.8 11 5.4 15.7 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) FAM76 PF16046.5 CDJ53282.1 - 9.9 5.4 31.0 0.014 14.7 12.1 3.2 3 0 0 3 3 3 0 FAM76 protein Helicase_C PF00271.31 CDJ53283.1 - 2.7e-20 72.7 0.0 2.7e-20 72.7 0.0 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ53283.1 - 7.4e-14 51.9 0.2 5.7e-12 45.7 0.0 3.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ53283.1 - 0.24 11.7 0.0 0.24 11.7 0.0 4.6 5 1 0 5 5 5 0 AAA domain TRAP_alpha PF03896.16 CDJ53283.1 - 0.91 8.7 5.3 2.1 7.5 5.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Folate_carrier PF01770.18 CDJ53283.1 - 2.5 6.7 3.6 6.1 5.5 3.6 1.6 1 0 0 1 1 1 0 Reduced folate carrier AP2 PF00847.20 CDJ53284.1 - 1.5e-06 28.3 0.4 1.5e-06 28.3 0.4 3.9 6 0 0 6 6 6 1 AP2 domain Activator_LAG-3 PF11498.8 CDJ53284.1 - 1.3 7.9 28.0 0.07 12.1 10.4 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 gag-asp_proteas PF13975.6 CDJ53286.1 - 6.2e-07 29.9 0.0 1.9e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDJ53286.1 - 1.3e-06 29.0 0.0 2.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ53286.1 - 0.016 15.5 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Cofac_haem_bdg PF04187.13 CDJ53286.1 - 0.03 14.3 0.3 0.073 13.1 0.0 1.8 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN RVP_2 PF08284.11 CDJ53286.1 - 0.031 14.0 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 CDJ53287.1 - 6.7e-21 74.8 0.0 9.8e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDJ53288.1 - 2.4e-11 43.9 0.0 4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDJ53288.1 - 0.033 13.9 0.4 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain Spt20 PF12090.8 CDJ53289.1 - 0.086 12.4 11.1 0.39 10.3 1.0 2.3 2 0 0 2 2 2 0 Spt20 family HECT PF00632.25 CDJ53291.1 - 1.9e-23 83.4 0.0 4.5e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Spt20 PF12090.8 CDJ53291.1 - 6.6e-05 22.6 26.7 0.00073 19.2 6.2 9.2 7 2 0 8 8 8 3 Spt20 family DUF2722 PF10846.8 CDJ53291.1 - 0.00036 19.6 8.6 0.00036 19.6 8.6 9.5 7 2 0 7 7 7 4 Protein of unknown function (DUF2722) SseC PF04888.12 CDJ53291.1 - 0.0037 16.9 15.7 0.0037 16.9 15.7 8.7 7 1 1 8 8 8 1 Secretion system effector C (SseC) like family SAPS PF04499.15 CDJ53291.1 - 0.015 14.1 0.0 0.015 14.1 0.0 4.6 2 2 1 4 4 4 0 SIT4 phosphatase-associated protein SPX PF03105.19 CDJ53292.1 - 0.65 9.9 48.7 0.037 14.0 20.7 2.1 2 0 0 2 2 2 0 SPX domain Apt1 PF10351.9 CDJ53292.1 - 5.2 5.8 54.0 4 6.2 15.3 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain zf-met PF12874.7 CDJ53293.1 - 4.5e-07 30.0 0.9 1.1e-06 28.9 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ53293.1 - 9.2e-07 29.0 1.4 1.9e-06 28.0 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDJ53293.1 - 0.0013 19.1 1.5 0.0013 19.1 1.5 2.4 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CDJ53293.1 - 0.0059 17.0 0.5 0.015 15.7 0.5 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-MYST PF17772.1 CDJ53293.1 - 0.01 15.4 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 MYST family zinc finger domain zf-C2H2_4 PF13894.6 CDJ53293.1 - 0.036 14.9 0.2 0.11 13.4 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.12 CDJ53293.1 - 0.12 12.5 1.3 0.33 11.1 1.3 1.7 1 0 0 1 1 1 0 DBF zinc finger Kinesin PF00225.23 CDJ53294.1 - 5.5e-56 189.9 0.0 1.5e-53 181.9 0.0 2.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ53294.1 - 1e-10 41.7 0.0 8.3e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Microtubule binding DUF4179 PF13786.6 CDJ53296.1 - 0.094 13.2 0.2 0.094 13.2 0.2 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4179) Herpes_US9 PF06072.11 CDJ53296.1 - 0.29 11.0 0.6 4.2 7.3 0.0 2.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 ALMT PF11744.8 CDJ53297.1 - 0.16 10.8 22.4 0.16 10.8 22.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CCDC53 PF10152.9 CDJ53297.1 - 0.25 11.7 26.3 0.31 11.5 26.3 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex NPR3 PF03666.13 CDJ53297.1 - 0.54 9.0 27.3 0.57 8.9 27.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 CDJ53297.1 - 0.64 8.9 17.7 0.69 8.8 17.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tim54 PF11711.8 CDJ53297.1 - 0.78 8.5 23.5 0.92 8.2 23.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3306 PF11748.8 CDJ53297.1 - 1.4 9.8 27.6 1.9 9.4 27.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) FAM60A PF15396.6 CDJ53297.1 - 1.5 8.8 25.2 1.6 8.7 25.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF2370 PF10176.9 CDJ53297.1 - 1.7 8.2 14.9 2.1 8.0 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) RR_TM4-6 PF06459.12 CDJ53297.1 - 1.7 8.4 31.9 1.9 8.3 31.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.7 CDJ53297.1 - 2.3 8.4 38.3 2.8 8.2 38.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) PPL5 PF18168.1 CDJ53297.1 - 2.6 7.3 19.7 2.8 7.1 19.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Kei1 PF08552.11 CDJ53297.1 - 2.8 7.8 17.8 3.6 7.4 17.8 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 HCO3_cotransp PF00955.21 CDJ53297.1 - 3.1 6.5 13.9 3.3 6.4 13.9 1.0 1 0 0 1 1 1 0 HCO3- transporter family FAM76 PF16046.5 CDJ53297.1 - 3.3 7.0 29.4 4.9 6.4 29.4 1.3 1 0 0 1 1 1 0 FAM76 protein DUF3295 PF11702.8 CDJ53297.1 - 3.4 6.9 26.8 3.7 6.8 26.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CSG2 PF16965.5 CDJ53297.1 - 3.7 6.4 16.2 4.3 6.2 16.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2828 PF11443.8 CDJ53297.1 - 5.4 5.0 29.3 6 4.8 29.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Gti1_Pac2 PF09729.9 CDJ53297.1 - 5.4 7.1 26.3 6.5 6.8 26.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family eIF-3_zeta PF05091.12 CDJ53297.1 - 5.9 5.8 38.7 7 5.5 38.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DAG_kinase_N PF14513.6 CDJ53297.1 - 6 7.1 28.3 7.4 6.8 28.3 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus CLN3 PF02487.17 CDJ53297.1 - 6.9 5.6 24.3 8.4 5.3 24.3 1.0 1 0 0 1 1 1 0 CLN3 protein Endostatin PF06482.11 CDJ53297.1 - 7 6.0 28.2 8.1 5.8 28.2 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4050 PF13259.6 CDJ53297.1 - 7.3 6.9 24.9 8.7 6.6 24.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DDRGK PF09756.9 CDJ53297.1 - 7.4 6.1 41.6 9.1 5.8 41.6 1.1 1 0 0 1 1 1 0 DDRGK domain Membralin PF09746.9 CDJ53297.1 - 7.8 5.4 21.0 8.6 5.3 21.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein Presenilin PF01080.17 CDJ53297.1 - 8.1 5.1 38.4 8.7 5.0 38.4 1.0 1 0 0 1 1 1 0 Presenilin Peptidase_S15 PF02129.18 CDJ53297.1 - 8.6 5.9 23.0 10 5.6 23.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SLC12 PF03522.15 CDJ53297.1 - 9.7 5.1 31.8 10 5.0 31.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 EPL1 PF10513.9 CDJ53298.1 - 0.0019 18.6 2.5 0.0019 18.6 2.5 4.3 2 1 2 4 4 4 1 Enhancer of polycomb-like Pkinase PF00069.25 CDJ53300.1 - 4.6e-56 190.1 0.1 5.8e-56 189.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ53300.1 - 3.1e-16 59.4 0.0 4.3e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ53300.1 - 4.4e-08 33.3 0.1 6.4e-06 26.3 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ53300.1 - 0.0014 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDJ53300.1 - 0.013 15.1 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 CDJ53300.1 - 0.019 13.8 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 CDJ53300.1 - 0.052 13.1 0.1 0.079 12.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 CDJ53300.1 - 0.053 12.8 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 CDJ53300.1 - 0.15 11.6 0.3 0.42 10.2 0.1 1.9 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CbiD PF01888.17 CDJ53300.1 - 0.26 10.6 1.7 0.41 9.9 1.7 1.3 1 0 0 1 1 1 0 CbiD Tim54 PF11711.8 CDJ53302.1 - 2.8 6.7 30.8 3.6 6.3 30.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ThiF PF00899.21 CDJ53303.1 - 0.0022 17.4 0.1 0.0031 16.9 0.1 1.4 1 0 0 1 1 1 1 ThiF family DUF508 PF04370.12 CDJ53303.1 - 0.44 10.3 4.3 0.53 10.0 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF508) SR-25 PF10500.9 CDJ53303.1 - 2.1 7.9 18.0 2.6 7.6 18.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 CDJ53303.1 - 5.8 7.8 19.9 0.13 13.1 5.5 2.1 2 0 0 2 2 2 0 Chorion family 2 Period_C PF12114.8 CDJ53303.1 - 7.9 6.0 13.6 9.1 5.8 13.6 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF3464 PF11947.8 CDJ53304.1 - 4.4e-05 23.3 3.4 4.4e-05 23.3 3.4 3.2 1 1 0 2 2 1 1 Photosynthesis affected mutant 68 DUF4746 PF15928.5 CDJ53304.1 - 0.0024 17.4 3.3 0.0024 17.4 3.3 2.4 2 1 0 2 2 1 1 Domain of unknown function (DUF4746) AP3D1 PF06375.11 CDJ53304.1 - 0.0042 17.3 6.6 0.0042 17.3 6.6 3.0 2 1 1 3 3 1 1 AP-3 complex subunit delta-1 DUF2052 PF09747.9 CDJ53304.1 - 0.044 13.9 39.0 0.084 13.0 8.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TFIIA PF03153.13 CDJ53304.1 - 0.14 12.1 81.7 0.26 11.2 27.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ53304.1 - 0.19 10.5 43.8 0.054 12.3 10.0 2.0 2 0 0 2 2 2 0 Presenilin Vfa1 PF08432.10 CDJ53304.1 - 0.29 11.5 36.1 1.1 9.5 10.9 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.12 CDJ53304.1 - 0.35 10.2 28.6 0.4 10.0 12.3 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger YABBY PF04690.13 CDJ53304.1 - 0.46 11.0 23.1 0.48 11.0 7.1 2.3 2 0 0 2 2 2 0 YABBY protein NPR3 PF03666.13 CDJ53304.1 - 0.56 8.9 30.9 0.12 11.1 4.5 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5427 PF10310.9 CDJ53304.1 - 0.62 9.0 36.7 1.1 8.1 9.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5427) RNA_pol_Rpc4 PF05132.14 CDJ53304.1 - 0.76 10.2 28.5 0.42 11.0 11.8 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Cwf_Cwc_15 PF04889.12 CDJ53304.1 - 0.77 9.5 36.9 0.041 13.6 10.5 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RP-C_C PF11800.8 CDJ53304.1 - 1 9.4 26.0 0.13 12.4 3.6 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region SRP-alpha_N PF04086.13 CDJ53304.1 - 2.6 7.9 35.3 0.74 9.7 7.2 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal V_ATPase_I PF01496.19 CDJ53304.1 - 2.8 5.7 35.7 0.023 12.6 5.6 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Membralin PF09746.9 CDJ53304.1 - 3.6 6.5 21.3 0.5 9.4 2.6 2.1 2 0 0 2 2 2 0 Tumour-associated protein Mpp10 PF04006.12 CDJ53304.1 - 3.9 5.8 47.6 12 4.2 47.5 1.5 1 1 1 2 2 2 0 Mpp10 protein RR_TM4-6 PF06459.12 CDJ53304.1 - 4.5 7.0 41.7 4.1 7.1 23.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.10 CDJ53304.1 - 4.7 6.5 37.1 0.41 10.0 9.5 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 AAA_11 PF13086.6 CDJ53304.1 - 5.8 6.6 31.1 0.61 9.8 5.7 2.1 2 0 0 2 2 2 0 AAA domain Endostatin PF06482.11 CDJ53304.1 - 6 6.2 27.2 1.3 8.4 5.6 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Ribosomal_60s PF00428.19 CDJ53304.1 - 6.9 7.3 13.9 5.3 7.7 0.2 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein CLN3 PF02487.17 CDJ53304.1 - 7 5.6 24.5 1 8.4 4.3 2.2 2 0 0 2 2 2 0 CLN3 protein CAC1F_C PF16885.5 CDJ53304.1 - 9.5 5.8 25.1 1.1 8.9 3.0 2.1 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term Trp_oprn_chp PF09534.10 CDJ53305.1 - 0.004 17.0 8.9 0.0052 16.6 8.9 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FHIPEP PF00771.20 CDJ53305.1 - 0.023 13.2 5.9 0.027 13.0 5.9 1.1 1 0 0 1 1 1 0 FHIPEP family RskA PF10099.9 CDJ53305.1 - 0.036 14.3 24.9 0.049 13.9 24.9 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SprA-related PF12118.8 CDJ53305.1 - 0.1 11.7 32.2 0.11 11.6 32.2 1.1 1 0 0 1 1 1 0 SprA-related family BAF1_ABF1 PF04684.13 CDJ53305.1 - 0.22 10.6 21.0 0.3 10.1 21.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ53305.1 - 0.26 11.3 28.7 0.31 11.0 28.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BSP_II PF05432.11 CDJ53305.1 - 0.29 10.8 14.9 0.36 10.5 14.9 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) JUPITER PF17054.5 CDJ53305.1 - 1 8.8 19.6 1.3 8.5 19.6 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter DUF5423 PF17461.2 CDJ53305.1 - 1.8 7.3 25.8 2.2 7.1 25.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) RAP1 PF07218.11 CDJ53305.1 - 2.6 6.2 19.4 2.9 6.1 19.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF966 PF06136.13 CDJ53305.1 - 4.9 6.8 25.4 6 6.5 25.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PPP4R2 PF09184.11 CDJ53305.1 - 6.2 6.3 16.5 7.3 6.1 16.5 1.1 1 0 0 1 1 1 0 PPP4R2 CCSAP PF15748.5 CDJ53305.1 - 6.8 6.8 25.9 9.5 6.3 25.9 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4834 PF16118.5 CDJ53305.1 - 6.9 7.7 19.2 5.6 8.0 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PI3K_1B_p101 PF10486.9 CDJ53305.1 - 8.8 4.0 23.7 10 3.7 23.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 CDJ53305.1 - 9.1 4.9 22.2 13 4.4 22.2 1.3 1 0 0 1 1 1 0 Presenilin DUF719 PF05334.13 CDJ53306.1 - 0.025 14.8 9.3 0.027 14.7 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) SpoIIP PF07454.11 CDJ53306.1 - 0.05 13.1 13.2 0.051 13.0 13.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pex14_N PF04695.13 CDJ53306.1 - 0.057 14.1 22.0 0.062 14.0 22.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EIIBC-GUT_N PF03612.14 CDJ53306.1 - 0.061 13.1 9.9 0.059 13.1 9.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 CDJ53306.1 - 0.072 11.8 14.1 0.063 12.0 14.1 1.0 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CDJ53306.1 - 0.08 13.1 10.7 0.095 12.9 10.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TERB2 PF15101.6 CDJ53306.1 - 0.08 13.0 19.2 0.081 13.0 19.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Connexin PF00029.19 CDJ53306.1 - 0.087 12.6 8.5 0.077 12.7 8.5 1.1 1 0 0 1 1 1 0 Connexin DDHD PF02862.17 CDJ53306.1 - 0.12 12.5 11.9 0.12 12.5 11.9 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 CDJ53306.1 - 0.15 11.9 11.8 0.14 12.0 11.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 CDJ53306.1 - 0.15 12.0 37.3 0.15 12.1 37.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 CDJ53306.1 - 0.21 12.0 13.8 0.21 12.0 13.8 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PAT1 PF09770.9 CDJ53306.1 - 0.22 9.7 24.5 0.2 9.9 24.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rxt3 PF08642.10 CDJ53306.1 - 0.3 11.8 5.2 0.31 11.8 5.2 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 eIF-3_zeta PF05091.12 CDJ53306.1 - 0.31 10.0 20.5 0.29 10.0 20.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.6 CDJ53306.1 - 0.41 10.6 8.9 0.41 10.6 8.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Coilin_N PF15862.5 CDJ53306.1 - 0.43 10.4 15.1 0.59 9.9 15.1 1.3 1 0 0 1 1 1 0 Coilin N-terminus EOS1 PF12326.8 CDJ53306.1 - 0.45 10.4 6.4 0.45 10.4 6.4 1.1 1 0 0 1 1 1 0 N-glycosylation protein Band_3_cyto PF07565.13 CDJ53306.1 - 0.53 10.0 12.3 0.51 10.1 12.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SLC12 PF03522.15 CDJ53306.1 - 0.62 9.0 15.5 0.71 8.8 15.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_U57 PF05582.12 CDJ53306.1 - 0.64 9.2 8.3 0.58 9.4 8.3 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF429 PF04250.13 CDJ53306.1 - 0.66 9.7 4.9 0.73 9.6 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF429) DUF3408 PF11888.8 CDJ53306.1 - 0.69 10.1 15.0 0.82 9.8 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF1980 PF09323.10 CDJ53306.1 - 0.69 9.8 9.4 0.68 9.8 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Ctr PF04145.15 CDJ53306.1 - 0.78 10.3 7.6 0.76 10.4 7.6 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Suf PF05843.14 CDJ53306.1 - 0.83 9.6 20.5 0.87 9.5 20.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4407 PF14362.6 CDJ53306.1 - 0.86 8.9 15.2 0.77 9.1 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CobT PF06213.12 CDJ53306.1 - 0.88 8.9 22.5 1.2 8.5 22.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFB6 PF17110.5 CDJ53306.1 - 0.9 9.3 8.1 0.92 9.2 8.1 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH AAA_23 PF13476.6 CDJ53306.1 - 0.96 9.9 16.6 0.94 9.9 16.6 1.1 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 CDJ53306.1 - 0.97 9.4 10.4 0.9 9.5 10.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Baculo_PP31 PF05311.11 CDJ53306.1 - 1 8.8 13.3 1 8.8 13.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF2126 PF09899.9 CDJ53306.1 - 1 7.3 10.0 1.1 7.2 10.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2370 PF10176.9 CDJ53306.1 - 1.2 8.8 8.0 1.3 8.6 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) SID-1_RNA_chan PF13965.6 CDJ53306.1 - 1.2 7.4 5.3 1.2 7.5 5.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AIF_C PF14721.6 CDJ53306.1 - 1.4 9.3 11.2 1.6 9.1 11.2 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ureide_permease PF07168.11 CDJ53306.1 - 1.6 7.4 6.0 1.6 7.4 6.0 1.1 1 0 0 1 1 1 0 Ureide permease Peroxin-13_N PF04088.13 CDJ53306.1 - 1.8 8.9 8.3 2 8.7 8.3 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region HA2 PF04408.23 CDJ53306.1 - 1.8 8.9 7.0 2.4 8.5 7.0 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) FAM176 PF14851.6 CDJ53306.1 - 2 8.0 9.5 2.3 7.9 9.5 1.2 1 0 0 1 1 1 0 FAM176 family Serinc PF03348.15 CDJ53306.1 - 2.3 7.0 8.7 2.2 7.1 8.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2828 PF11443.8 CDJ53306.1 - 2.5 6.1 14.8 2.5 6.1 14.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Folate_carrier PF01770.18 CDJ53306.1 - 2.6 6.7 9.0 2.9 6.5 9.0 1.0 1 0 0 1 1 1 0 Reduced folate carrier V_ATPase_I PF01496.19 CDJ53306.1 - 3.1 5.6 16.0 3 5.6 16.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DcuA_DcuB PF03605.14 CDJ53306.1 - 3.1 6.6 3.9 2.7 6.8 3.9 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Gti1_Pac2 PF09729.9 CDJ53306.1 - 3.2 7.8 12.1 3.5 7.7 12.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family CSG2 PF16965.5 CDJ53306.1 - 3.5 6.5 8.1 3.8 6.3 8.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator ALMT PF11744.8 CDJ53306.1 - 5.8 5.6 11.6 6.1 5.6 11.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 CDJ53306.1 - 6.1 6.0 7.1 5.7 6.0 7.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 CDJ53306.1 - 6.6 6.2 11.4 7.4 6.0 11.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RICTOR_N PF14664.6 CDJ53306.1 - 6.7 5.6 7.2 7.1 5.5 7.2 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF775 PF05603.12 CDJ53306.1 - 7.1 6.1 16.5 11 5.5 16.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ndc1_Nup PF09531.10 CDJ53306.1 - 7.5 5.1 13.4 7.3 5.2 13.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tim54 PF11711.8 CDJ53306.1 - 8.6 5.0 15.8 10 4.8 15.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S49_N PF08496.10 CDJ53306.1 - 9.5 6.3 15.5 12 6.0 15.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TFIIA PF03153.13 CDJ53307.1 - 0.0021 18.1 35.9 0.0021 18.1 35.9 19.3 3 2 11 17 17 17 2 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ53308.1 - 0.00036 20.9 1.5 0.00036 20.9 1.5 6.0 4 2 1 5 5 5 3 Anti-sigma-K factor rskA CBM_14 PF01607.24 CDJ53308.1 - 0.0068 16.5 0.1 0.014 15.6 0.1 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF4366 PF14283.6 CDJ53308.1 - 0.037 14.1 2.3 0.93 9.5 0.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4366) Filament_head PF04732.14 CDJ53308.1 - 0.43 11.5 43.3 1.5 9.8 6.3 3.7 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region Secretin_N_2 PF07655.13 CDJ53308.1 - 1.7 9.3 41.8 3.1 8.4 15.8 3.9 3 0 0 3 3 3 0 Secretin N-terminal domain DUF4667 PF15700.5 CDJ53308.1 - 2.8 8.0 35.2 0.11 12.6 1.9 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4667) Asp_protease_2 PF13650.6 CDJ53309.1 - 8e-10 39.2 0.0 1.7e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ53309.1 - 3.4e-09 37.1 0.0 9e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ53309.1 - 9.5e-07 28.7 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CDJ53309.1 - 0.00094 19.5 0.1 0.0078 16.5 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 CDJ53309.1 - 0.059 13.7 5.4 0.1 12.9 0.0 2.9 3 1 0 3 3 3 0 Retrotransposon gag protein K_channel_TID PF07941.11 CDJ53310.1 - 0.0079 16.6 16.7 0.0079 16.6 16.7 10.4 7 3 2 9 9 9 1 Potassium channel Kv1.4 tandem inactivation domain FTCD_N PF07837.12 CDJ53310.1 - 0.0081 16.0 4.6 0.0081 16.0 4.6 4.2 3 1 1 4 4 4 1 Formiminotransferase domain, N-terminal subdomain IMCp PF12314.8 CDJ53310.1 - 0.017 15.4 13.7 0.051 13.9 12.9 2.1 1 1 1 2 2 2 0 Inner membrane complex protein SUIM_assoc PF16619.5 CDJ53310.1 - 0.019 15.0 6.2 0.019 15.0 6.2 11.6 3 2 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF3402 PF11882.8 CDJ53311.1 - 0.00036 19.8 5.6 0.00036 19.8 5.6 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3402) Otopetrin PF03189.13 CDJ53311.1 - 0.23 10.2 10.9 1.1 8.0 8.4 2.6 3 0 0 3 3 3 0 Otopetrin CAF1 PF04857.20 CDJ53311.1 - 0.26 10.4 19.2 4.8 6.3 15.8 3.0 3 0 0 3 3 3 0 CAF1 family ribonuclease DUF4400 PF14348.6 CDJ53313.1 - 0.0033 17.0 0.4 0.0033 17.0 0.4 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4400) TFIIA PF03153.13 CDJ53313.1 - 0.0071 16.4 5.2 0.01 15.8 5.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PBP1_TM PF14812.6 CDJ53313.1 - 0.035 14.5 0.0 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AIM3 PF17096.5 CDJ53313.1 - 0.038 14.9 2.3 0.091 13.7 2.3 1.6 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Tim54 PF11711.8 CDJ53313.1 - 0.056 12.2 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RSF PF14876.6 CDJ53313.1 - 0.058 12.4 0.2 0.085 11.8 0.2 1.1 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator DUF2722 PF10846.8 CDJ53313.1 - 0.083 11.8 7.4 0.12 11.3 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ53313.1 - 0.23 11.0 13.6 0.36 10.4 13.6 1.2 1 0 0 1 1 1 0 Spt20 family Glyco_hydro_9 PF00759.19 CDJ53313.1 - 0.44 9.9 3.2 0.76 9.1 3.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 DUF4746 PF15928.5 CDJ53313.1 - 0.64 9.4 4.9 1 8.7 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TMEM51 PF15345.6 CDJ53313.1 - 0.83 9.5 6.0 1.9 8.3 6.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 DUF702 PF05142.12 CDJ53313.1 - 2.2 8.7 6.4 1.5 9.3 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) UPF0560 PF10577.9 CDJ53313.1 - 6.2 5.2 8.4 9.5 4.6 8.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FAM60A PF15396.6 CDJ53315.1 - 6.7 6.6 13.8 7.2 6.6 13.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Flagellar_rod PF05149.12 CDJ53315.1 - 8.1 5.8 29.9 8.8 5.7 29.9 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein M16C_assoc PF08367.11 CDJ53316.1 - 3.8e-49 167.1 0.3 6.3e-49 166.4 0.3 1.4 1 0 0 1 1 1 1 Peptidase M16C associated RE_HindIII PF09518.10 CDJ53316.1 - 0.0026 17.0 0.3 0.0059 15.9 0.3 1.5 1 0 0 1 1 1 1 HindIII restriction endonuclease Peptidase_M16_C PF05193.21 CDJ53316.1 - 0.064 13.3 2.1 6.8 6.7 0.1 3.3 3 0 0 3 3 3 0 Peptidase M16 inactive domain AF-4 PF05110.13 CDJ53316.1 - 2.9 5.8 15.9 5.4 5.0 15.9 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Secretin_N_2 PF07655.13 CDJ53316.1 - 4.4 7.9 15.9 10 6.8 15.9 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Peptidase_M16_C PF05193.21 CDJ53317.1 - 1.3e-05 25.3 0.0 3.6e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDJ53317.1 - 0.0028 17.6 0.0 0.0028 17.6 0.0 2.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) SpoIIP PF07454.11 CDJ53318.1 - 0.011 15.2 8.3 0.011 15.2 8.3 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2126 PF09899.9 CDJ53318.1 - 0.02 13.0 10.2 0.031 12.4 10.2 1.3 1 1 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CCDC53 PF10152.9 CDJ53318.1 - 0.073 13.5 20.0 0.3 11.5 20.0 1.8 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF572 PF04502.13 CDJ53318.1 - 0.17 11.5 16.1 0.37 10.4 16.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF966 PF06136.13 CDJ53318.1 - 0.24 11.1 14.8 0.33 10.6 14.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RPA43_OB PF17875.1 CDJ53318.1 - 0.35 11.5 6.7 0.23 12.1 2.9 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I BRF1 PF07741.13 CDJ53318.1 - 0.44 10.9 12.8 0.23 11.8 7.7 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF1980 PF09323.10 CDJ53318.1 - 0.57 10.1 7.4 0.26 11.2 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Rxt3 PF08642.10 CDJ53318.1 - 0.59 10.9 6.6 0.38 11.5 1.9 2.5 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Zip PF02535.22 CDJ53318.1 - 0.93 8.6 3.7 1.4 8.1 3.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Draxin PF15550.6 CDJ53318.1 - 0.99 9.2 16.2 1.4 8.7 16.2 1.2 1 0 0 1 1 1 0 Draxin HA2 PF04408.23 CDJ53318.1 - 1.7 9.0 10.5 0.34 11.2 5.3 2.3 2 0 0 2 2 2 0 Helicase associated domain (HA2) Ureide_permease PF07168.11 CDJ53318.1 - 2 7.1 5.0 4.1 6.1 5.0 1.5 1 0 0 1 1 1 0 Ureide permease Sec62 PF03839.16 CDJ53318.1 - 2.9 7.4 11.9 0.26 10.8 6.4 1.9 2 0 0 2 2 2 0 Translocation protein Sec62 DUF4770 PF15994.5 CDJ53318.1 - 3.3 7.9 20.2 0.36 11.0 9.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Connexin PF00029.19 CDJ53318.1 - 3.6 7.3 13.5 0.57 9.9 8.7 1.9 2 0 0 2 2 2 0 Connexin Serinc PF03348.15 CDJ53318.1 - 3.9 6.3 8.5 5.6 5.8 8.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) EMC3_TMCO1 PF01956.16 CDJ53318.1 - 5.6 6.7 18.3 6.1 6.6 11.8 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Orf78 PF06024.12 CDJ53318.1 - 8.5 6.7 9.5 1.7 9.0 4.1 2.4 2 0 0 2 2 2 0 Orf78 (ac78) PPL5 PF18168.1 CDJ53318.1 - 8.9 5.5 14.1 0.33 10.2 8.2 1.6 2 0 0 2 2 2 0 Prim-pol family 5 Asparaginase_2 PF01112.18 CDJ53318.1 - 9.9 5.1 9.8 4.8 6.1 6.8 1.8 2 0 0 2 2 2 0 Asparaginase ubiquitin PF00240.23 CDJ53319.1 - 8.2e-21 73.5 0.3 9e-21 73.4 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ53319.1 - 7.9e-08 32.0 0.1 9.4e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ53319.1 - 6.2e-06 26.6 0.5 2.9e-05 24.4 0.5 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 CDJ53319.1 - 0.0094 16.5 0.1 0.011 16.3 0.1 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 CDJ53319.1 - 0.14 12.1 0.1 0.17 11.8 0.1 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ53319.1 - 0.16 12.1 0.1 0.51 10.5 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RhlB PF12300.8 CDJ53320.1 - 0.0007 19.8 8.3 0.0007 19.8 8.3 5.1 5 0 0 5 5 5 1 ATP-dependent RNA helicase RhlB Spt20 PF12090.8 CDJ53320.1 - 0.0012 18.5 12.2 0.0012 18.5 12.2 6.5 6 1 0 6 6 6 3 Spt20 family DUF4171 PF13775.6 CDJ53320.1 - 0.0031 17.9 6.6 0.0031 17.9 6.6 6.2 5 2 0 6 6 6 1 Domain of unknown function (DUF4171) LCD1 PF09798.9 CDJ53320.1 - 0.052 12.1 0.0 0.052 12.1 0.0 2.7 2 1 0 2 2 2 0 DNA damage checkpoint protein Peptidase_S64 PF08192.11 CDJ53320.1 - 7.6 4.9 44.2 3.4 6.0 15.2 3.4 3 0 0 3 3 3 0 Peptidase family S64 SR-25 PF10500.9 CDJ53321.1 - 4.8e-06 26.4 11.7 4.8e-06 26.4 11.7 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.8 CDJ53321.1 - 4.4e-05 22.7 12.1 5e-05 22.5 12.1 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Med3 PF11593.8 CDJ53321.1 - 0.017 14.3 12.4 0.026 13.7 12.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal OmpH PF03938.14 CDJ53321.1 - 0.12 12.7 14.5 0.16 12.3 14.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Suf PF05843.14 CDJ53321.1 - 0.14 12.2 4.5 0.13 12.3 4.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF755 PF05501.11 CDJ53322.1 - 0.0076 16.5 15.6 0.0076 16.5 15.6 5.2 3 2 2 5 5 5 1 Domain of unknown function (DUF755) Fer2_3 PF13085.6 CDJ53324.1 - 3.4e-05 23.8 0.1 6.5e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TSKS PF15358.6 CDJ53324.1 - 0.00067 18.2 0.6 0.00067 18.2 0.6 1.5 2 0 0 2 2 2 1 Testis-specific serine kinase substrate Tmemb_cc2 PF10267.9 CDJ53324.1 - 0.0076 15.4 3.9 0.0092 15.2 3.9 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein FAM76 PF16046.5 CDJ53324.1 - 0.025 13.9 5.5 0.033 13.6 5.5 1.1 1 0 0 1 1 1 0 FAM76 protein Chorion_2 PF03964.15 CDJ53324.1 - 0.031 15.1 19.5 0.78 10.6 2.1 3.5 3 0 0 3 3 3 0 Chorion family 2 ASD2 PF08687.11 CDJ53324.1 - 0.035 13.7 3.3 0.046 13.3 3.3 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 IMUP PF15761.5 CDJ53324.1 - 0.037 14.7 6.1 0.037 14.7 6.1 2.4 3 0 0 3 3 2 0 Immortalisation up-regulated protein PRIMA1 PF16101.5 CDJ53324.1 - 0.038 14.0 5.9 0.099 12.7 5.9 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Macoilin PF09726.9 CDJ53324.1 - 0.043 12.4 7.8 0.056 12.0 7.8 1.1 1 0 0 1 1 1 0 Macoilin family Inj_translocase PF16928.5 CDJ53324.1 - 0.49 9.8 5.5 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome ARA70 PF12489.8 CDJ53324.1 - 2.2 8.5 11.6 2.5 8.3 0.8 2.1 2 0 0 2 2 2 0 Nuclear coactivator SR-25 PF10500.9 CDJ53324.1 - 4.6 6.8 26.7 9.4 5.8 24.3 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_L5_C PF00673.21 CDJ53325.1 - 2.4e-22 78.9 0.0 3.8e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CDJ53325.1 - 2.6e-21 75.7 0.0 5.1e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CDJ53325.1 - 0.086 12.6 0.2 0.086 12.6 0.2 1.7 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain V-SNARE_C PF12352.8 CDJ53325.1 - 0.1 12.9 0.6 0.39 11.1 0.1 2.0 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus ADH_zinc_N PF00107.26 CDJ53326.1 - 4.5e-24 84.9 0.0 7.1e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDJ53326.1 - 2.2e-12 46.8 8.1 2.2e-12 46.8 8.1 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CDJ53326.1 - 7.8e-05 22.3 0.1 0.00017 21.1 0.1 1.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 CDJ53326.1 - 0.0024 17.5 0.1 0.0038 16.8 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 CDJ53326.1 - 0.0089 15.3 0.6 0.014 14.7 0.2 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CDJ53326.1 - 0.23 10.8 0.2 1 8.7 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PliI PF16743.5 CDJ53329.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Periplasmic lysozyme inhibitor of I-type lysozyme Pkinase PF00069.25 CDJ53330.1 - 2.3e-58 197.6 0.0 3e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ53330.1 - 8.2e-30 103.9 0.0 1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ53330.1 - 6.1e-06 25.7 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ53330.1 - 7.5e-06 25.5 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ53330.1 - 0.00073 19.5 0.0 0.44 10.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Cytokin-bind PF09265.10 CDJ53330.1 - 0.046 13.1 0.1 0.14 11.5 0.0 1.8 3 0 0 3 3 3 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding RRM_1 PF00076.22 CDJ53331.1 - 4.8e-18 64.7 0.1 6.7e-18 64.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ53331.1 - 0.044 13.8 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4116 PF13475.6 CDJ53333.1 - 0.22 11.3 0.0 0.47 10.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Porin_3 PF01459.22 CDJ53335.1 - 1.8e-17 63.7 0.0 2.3e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin NIF PF03031.18 CDJ53336.1 - 1.4e-21 76.9 0.0 3.3e-21 75.7 0.0 1.7 1 1 1 2 2 2 1 NLI interacting factor-like phosphatase Ndc1_Nup PF09531.10 CDJ53336.1 - 1.5 7.4 6.9 2.2 6.9 6.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 CDJ53336.1 - 9.7 6.1 15.1 25 4.7 15.1 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Steroid_dh PF02544.16 CDJ53337.1 - 3.9e-33 114.6 10.7 5.3e-28 97.9 1.4 3.6 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase PSS PF03034.15 CDJ53338.1 - 4.5e-74 249.6 11.1 4.5e-74 249.6 11.1 1.6 2 0 0 2 2 2 1 Phosphatidyl serine synthase DUF4834 PF16118.5 CDJ53338.1 - 0.32 12.0 9.7 60 4.7 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) WBP-1 PF11669.8 CDJ53338.1 - 0.34 11.5 7.7 0.44 11.2 0.1 3.2 2 0 0 2 2 2 0 WW domain-binding protein 1 Zip PF02535.22 CDJ53338.1 - 2.3 7.3 4.4 0.99 8.6 0.5 2.3 3 0 0 3 3 3 0 ZIP Zinc transporter DDHD PF02862.17 CDJ53338.1 - 2.7 8.1 10.5 0.23 11.6 4.8 1.8 2 0 0 2 2 2 0 DDHD domain Androgen_recep PF02166.16 CDJ53338.1 - 8.1 5.2 25.8 12 4.6 25.8 1.1 1 0 0 1 1 1 0 Androgen receptor EPL1 PF10513.9 CDJ53338.1 - 8.4 6.8 13.5 1.6 9.1 7.6 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like Nitrate_red_gam PF02665.14 CDJ53340.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FAM199X PF15814.5 CDJ53343.1 - 0.026 13.6 2.3 0.031 13.3 2.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X Nop53 PF07767.11 CDJ53343.1 - 0.2 11.0 11.1 0.2 11.0 11.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GrpE PF01025.19 CDJ53343.1 - 0.22 11.2 6.7 0.31 10.7 6.7 1.2 1 0 0 1 1 1 0 GrpE EMC3_TMCO1 PF01956.16 CDJ53343.1 - 0.31 10.8 2.2 0.39 10.4 2.2 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like TALPID3 PF15324.6 CDJ53343.1 - 0.55 7.8 7.3 0.64 7.6 7.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Ribosomal_60s PF00428.19 CDJ53343.1 - 1 10.0 32.4 2.2 8.9 11.0 2.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_S49_N PF08496.10 CDJ53343.1 - 2.9 7.9 11.5 0.078 13.0 5.7 1.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Chorion_2 PF03964.15 CDJ53343.1 - 4.1 8.3 14.3 0.33 11.8 5.9 2.3 2 0 0 2 2 2 0 Chorion family 2 SR-25 PF10500.9 CDJ53343.1 - 9.9 5.7 16.8 27 4.3 16.8 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CLN3 PF02487.17 CDJ53344.1 - 0.00033 19.8 3.4 0.05 12.6 1.0 2.1 2 0 0 2 2 2 2 CLN3 protein AAA_11 PF13086.6 CDJ53344.1 - 0.00055 19.8 7.5 0.14 12.0 6.5 2.1 2 0 0 2 2 2 2 AAA domain Neur_chan_memb PF02932.16 CDJ53344.1 - 0.0052 16.9 3.2 0.42 10.6 3.0 2.1 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ53344.1 - 0.012 15.7 51.6 0.018 15.0 26.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Otopetrin PF03189.13 CDJ53344.1 - 0.015 14.2 0.0 0.039 12.8 0.0 1.6 1 1 0 1 1 1 0 Otopetrin HAUS6_N PF14661.6 CDJ53344.1 - 0.015 14.9 21.9 0.05 13.2 12.9 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Tic110 PF16940.5 CDJ53344.1 - 0.04 12.4 6.2 0.069 11.6 6.2 1.5 1 0 0 1 1 1 0 Chloroplast envelope transporter Connexin PF00029.19 CDJ53344.1 - 0.042 13.6 9.1 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Connexin CDRT4 PF15213.6 CDJ53344.1 - 0.1 13.2 0.0 0.1 13.2 0.0 2.4 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein DUF4175 PF13779.6 CDJ53344.1 - 0.11 10.4 42.9 0.043 11.7 10.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) SpoIIP PF07454.11 CDJ53344.1 - 0.15 11.5 13.6 7 6.0 0.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) MecA PF05389.12 CDJ53344.1 - 0.15 11.7 8.7 3.3 7.3 7.2 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) PIP5K PF01504.18 CDJ53344.1 - 0.27 10.4 9.8 0.96 8.6 9.8 1.7 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase FAM60A PF15396.6 CDJ53344.1 - 0.36 10.8 11.3 2.6 8.0 7.6 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Orf78 PF06024.12 CDJ53344.1 - 0.37 11.1 11.3 4.7 7.6 0.1 2.6 2 0 0 2 2 2 0 Orf78 (ac78) CSG2 PF16965.5 CDJ53344.1 - 0.37 9.7 7.9 3.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator Peroxin-13_N PF04088.13 CDJ53344.1 - 0.69 10.2 8.0 12 6.1 5.0 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Scs3p PF10261.9 CDJ53344.1 - 1.3 8.5 7.5 0.91 9.0 0.1 2.2 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM RskA PF10099.9 CDJ53344.1 - 1.3 9.3 40.0 0.23 11.7 22.9 2.8 1 1 1 2 2 2 0 Anti-sigma-K factor rskA BORG_CEP PF14957.6 CDJ53344.1 - 1.7 9.8 10.0 27 6.0 6.8 2.2 2 0 0 2 2 2 0 Cdc42 effector Peptidase_S49_N PF08496.10 CDJ53344.1 - 1.8 8.6 17.7 6.8 6.7 10.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1980 PF09323.10 CDJ53344.1 - 2.6 7.9 8.5 17 5.2 4.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Coilin_N PF15862.5 CDJ53344.1 - 3.4 7.5 18.2 39 4.1 0.0 2.3 2 0 0 2 2 2 0 Coilin N-terminus Gti1_Pac2 PF09729.9 CDJ53344.1 - 4.3 7.4 11.9 34 4.5 8.6 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Afi1 PF07792.12 CDJ53344.1 - 4.4 7.8 14.0 21 5.6 0.1 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Exonuc_VII_L PF02601.15 CDJ53344.1 - 5.1 6.6 31.3 5.6 6.4 7.3 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit EPL1 PF10513.9 CDJ53344.1 - 5.8 7.3 20.8 8.1 6.8 0.5 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF2126 PF09899.9 CDJ53344.1 - 6.2 4.8 12.8 10 4.0 8.3 2.0 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) EIF4E-T PF10477.9 CDJ53344.1 - 6.4 5.5 29.7 1.8 7.3 6.5 2.1 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E SID-1_RNA_chan PF13965.6 CDJ53344.1 - 7.2 4.9 8.8 55 2.0 0.2 1.7 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 Rxt3 PF08642.10 CDJ53344.1 - 8.2 7.2 8.1 11 6.8 4.3 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 OATP PF03137.20 CDJ53344.1 - 8.8 4.5 10.3 2.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TERB2 PF15101.6 CDJ53344.1 - 9.9 6.1 27.7 4.6 7.2 15.5 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 RskA PF10099.9 CDJ53345.1 - 4.2e-08 33.7 3.3 4.2e-08 33.7 3.3 5.8 1 1 4 5 5 5 3 Anti-sigma-K factor rskA Activator_LAG-3 PF11498.8 CDJ53345.1 - 0.00016 20.8 24.0 0.00016 20.8 24.0 4.5 3 1 1 4 4 4 2 Transcriptional activator LAG-3 SR-25 PF10500.9 CDJ53345.1 - 0.0067 16.1 17.2 0.0067 16.1 17.2 4.8 1 1 3 4 4 4 2 Nuclear RNA-splicing-associated protein CNDH2_C PF16858.5 CDJ53345.1 - 5.2 6.9 34.8 0.65 9.8 13.2 2.9 2 1 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term AP2 PF00847.20 CDJ53346.1 - 0.00017 21.7 0.1 0.00017 21.7 0.1 3.1 3 0 0 3 3 3 1 AP2 domain Exonuc_VII_L PF02601.15 CDJ53346.1 - 0.95 9.0 55.9 0.053 13.1 15.7 3.1 3 0 0 3 3 3 0 Exonuclease VII, large subunit DUF1765 PF08578.10 CDJ53348.1 - 2.6e-14 53.7 0.5 5.5e-14 52.7 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) F-box-like PF12937.7 CDJ53349.1 - 5.1e-06 26.3 0.5 1.9e-05 24.4 0.1 2.3 1 1 1 2 2 2 1 F-box-like F-box PF00646.33 CDJ53349.1 - 0.0012 18.7 0.3 0.0012 18.7 0.3 3.1 3 0 0 3 3 3 1 F-box domain F-box_5 PF18511.1 CDJ53349.1 - 0.032 13.8 0.1 0.06 12.9 0.1 1.4 1 0 0 1 1 1 0 F-box Ribosomal_60s PF00428.19 CDJ53349.1 - 0.032 14.8 7.6 0.032 14.8 7.6 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein RNase_Zc3h12a PF11977.8 CDJ53352.1 - 1.9e-08 34.2 0.1 9.6e-08 31.9 0.0 2.3 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain DUF1645 PF07816.11 CDJ53354.1 - 0.0038 17.9 0.5 0.0038 17.9 0.5 4.3 4 2 0 4 4 4 3 Protein of unknown function (DUF1645) DUF3446 PF11928.8 CDJ53354.1 - 0.0084 16.4 7.5 0.0084 16.4 7.5 6.7 5 2 1 6 6 6 2 Early growth response N-terminal domain TrbM PF07424.11 CDJ53354.1 - 0.44 10.5 4.1 1.2 9.1 4.1 1.6 1 0 0 1 1 1 0 TrbM TCP PF03634.13 CDJ53354.1 - 1.1 9.8 33.1 2.5 8.6 4.5 3.6 3 0 0 3 3 3 0 TCP family transcription factor SPX PF03105.19 CDJ53355.1 - 0.0016 18.4 11.1 0.0016 18.4 11.1 2.7 2 1 0 2 2 2 1 SPX domain CaKB PF03185.15 CDJ53355.1 - 0.028 14.1 5.1 0.084 12.5 5.1 1.8 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit LMBR1 PF04791.16 CDJ53355.1 - 0.44 9.4 5.3 0.1 11.5 1.7 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF1980 PF09323.10 CDJ53355.1 - 1.7 8.5 11.7 4.8 7.1 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) OmpH PF03938.14 CDJ53355.1 - 2.6 8.4 66.2 0.47 10.8 30.7 4.1 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) DUF2232 PF09991.9 CDJ53355.1 - 6.2 5.9 7.8 14 4.8 0.9 3.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF521 PF04412.13 CDJ53356.1 - 0.016 13.9 4.1 0.029 13.1 4.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF521) Spt20 PF12090.8 CDJ53356.1 - 0.076 12.6 40.7 0.29 10.7 22.2 2.3 2 0 0 2 2 2 0 Spt20 family Cwf_Cwc_15 PF04889.12 CDJ53356.1 - 0.41 10.3 14.7 0.072 12.8 8.1 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SPX PF03105.19 CDJ53356.1 - 0.52 10.2 24.1 0.4 10.5 19.2 2.0 2 0 0 2 2 2 0 SPX domain SR-25 PF10500.9 CDJ53356.1 - 1.8 8.1 37.8 0.19 11.3 30.5 2.2 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Inj_translocase PF16928.5 CDJ53356.1 - 2.8 7.3 24.7 1.2 8.5 5.7 2.4 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome DUF2681 PF10883.8 CDJ53356.1 - 6.4 7.3 23.2 6.1 7.3 8.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) PAP1 PF08601.10 CDJ53356.1 - 8.2 6.0 31.7 21 4.7 31.7 1.6 1 1 0 1 1 1 0 Transcription factor PAP1 SR-25 PF10500.9 CDJ53357.1 - 0.009 15.6 15.2 0.009 15.6 15.2 3.3 2 2 1 3 3 3 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ53357.1 - 0.3 9.1 62.8 0.03 12.5 14.8 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein K_channel_TID PF07941.11 CDJ53358.1 - 0.026 15.0 9.2 0.026 15.0 9.2 8.5 6 3 1 7 7 7 0 Potassium channel Kv1.4 tandem inactivation domain Ribosomal_60s PF00428.19 CDJ53358.1 - 8.7 7.0 76.4 2.2 8.9 12.3 5.1 4 1 1 5 5 5 0 60s Acidic ribosomal protein SPO11_like PF03533.14 CDJ53359.1 - 0.023 14.8 0.0 0.081 13.0 0.0 1.9 1 0 0 1 1 1 0 SPO11 homologue N6_N4_Mtase PF01555.18 CDJ53362.1 - 0.00094 19.0 0.0 1.1 9.0 1.8 3.9 3 1 1 4 4 4 2 DNA methylase Mitofilin PF09731.9 CDJ53363.1 - 0.12 11.2 10.5 0.13 11.1 10.5 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SARAF PF06682.12 CDJ53363.1 - 0.16 11.6 4.9 0.17 11.5 4.9 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Pex14_N PF04695.13 CDJ53363.1 - 0.22 12.2 22.1 0.27 11.9 22.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BAT2_N PF07001.11 CDJ53363.1 - 0.88 10.0 14.8 1.2 9.5 14.8 1.3 1 0 0 1 1 1 0 BAT2 N-terminus DUF4551 PF15087.6 CDJ53363.1 - 0.88 8.3 4.8 0.87 8.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4366 PF14283.6 CDJ53363.1 - 1.2 9.1 4.6 2 8.4 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SOG2 PF10428.9 CDJ53363.1 - 3.7 6.6 13.9 3.7 6.7 13.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Spt20 PF12090.8 CDJ53363.1 - 4.6 6.8 14.0 5.4 6.6 14.0 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ53363.1 - 4.9 7.0 16.7 5.6 6.8 16.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ53363.1 - 8.5 5.4 13.1 10 5.1 13.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SRP-alpha_N PF04086.13 CDJ53363.1 - 9.2 6.1 9.4 10 6.0 9.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ndc1_Nup PF09531.10 CDJ53363.1 - 9.3 4.8 14.6 10 4.7 14.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nop14 PF04147.12 CDJ53364.1 - 0.24 9.6 26.7 1 7.5 0.5 2.1 2 0 0 2 2 2 0 Nop14-like family DUF755 PF05501.11 CDJ53365.1 - 0.0064 16.8 15.2 0.0064 16.8 15.2 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF755) DUF4667 PF15700.5 CDJ53365.1 - 0.24 11.5 13.8 0.31 11.1 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Peptidase_S30 PF01577.16 CDJ53365.1 - 0.77 9.3 4.4 0.95 9.0 4.4 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease AF-4 PF05110.13 CDJ53365.1 - 0.81 7.7 18.8 1 7.4 18.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ53365.1 - 1.5 8.4 25.1 3.4 7.2 25.1 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein HSD3 PF15244.6 CDJ53365.1 - 2.3 7.6 12.7 2.9 7.3 12.7 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 TFIIA PF03153.13 CDJ53365.1 - 2.5 8.0 21.7 3 7.7 21.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 CDJ53365.1 - 2.8 6.7 12.9 3.4 6.4 12.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CAML PF14963.6 CDJ53365.1 - 3.8 7.6 8.6 1 9.4 5.7 1.5 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand PAP1 PF08601.10 CDJ53365.1 - 4.5 6.9 18.9 5.3 6.7 18.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF572 PF04502.13 CDJ53365.1 - 4.6 6.8 9.9 5.4 6.5 9.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.9 CDJ53365.1 - 5.3 5.5 12.9 6.7 5.1 12.9 1.2 1 0 0 1 1 1 0 Macoilin family CDK2AP PF09806.9 CDJ53365.1 - 5.9 6.9 31.0 17 5.4 30.9 1.7 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4484 PF14831.6 CDJ53365.1 - 7.4 6.6 10.7 10 6.1 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Plasmodium_Vir PF05795.11 CDJ53365.1 - 7.9 5.8 7.4 9.5 5.5 7.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 CDJ53365.1 - 8.5 6.2 15.5 9.7 6.0 15.5 1.0 1 0 0 1 1 1 0 SPX domain SLC12 PF03522.15 CDJ53366.1 - 4.9 6.1 17.1 5.6 5.9 17.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 CDJ53366.1 - 5.1 6.2 12.3 6.6 5.8 12.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Synaptobrevin PF00957.21 CDJ53366.1 - 5.9 6.8 9.8 0.18 11.6 2.3 2.3 1 1 1 2 2 2 0 Synaptobrevin Raftlin PF15250.6 CDJ53366.1 - 6.2 5.5 17.8 7.2 5.2 17.8 1.0 1 0 0 1 1 1 0 Raftlin PAT1 PF09770.9 CDJ53367.1 - 0.061 11.6 36.5 0.07 11.4 36.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.13 CDJ53367.1 - 0.26 10.9 36.5 0.39 10.3 36.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4775 PF16001.5 CDJ53367.1 - 0.96 8.8 32.5 1.3 8.4 32.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) PIN_12 PF16289.5 CDJ53367.1 - 2.8 8.4 9.6 4.1 7.9 9.6 1.2 1 0 0 1 1 1 0 PIN domain DUF3292 PF11696.8 CDJ53367.1 - 3.6 5.8 14.8 4.6 5.5 14.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF1645 PF07816.11 CDJ53368.1 - 0.0001 23.0 7.6 0.0001 23.0 7.6 4.8 3 2 0 3 3 1 1 Protein of unknown function (DUF1645) DUF4834 PF16118.5 CDJ53368.1 - 0.00018 22.4 5.1 0.00018 22.4 5.1 5.6 5 1 1 6 6 5 1 Domain of unknown function (DUF4834) LTV PF04180.14 CDJ53368.1 - 0.0055 16.5 3.9 0.0055 16.5 3.9 3.7 4 0 0 4 4 3 1 Low temperature viability protein TctB PF07331.11 CDJ53368.1 - 0.0088 16.3 0.0 0.0088 16.3 0.0 2.9 4 1 0 4 4 3 1 Tripartite tricarboxylate transporter TctB family Connexin PF00029.19 CDJ53368.1 - 0.013 15.3 0.9 0.013 15.3 0.9 3.5 3 1 0 3 3 2 0 Connexin EMC3_TMCO1 PF01956.16 CDJ53368.1 - 0.013 15.2 1.9 0.013 15.2 1.9 3.1 3 1 0 3 3 2 0 Integral membrane protein EMC3/TMCO1-like Tetraspanin PF00335.20 CDJ53368.1 - 0.017 14.8 0.5 0.065 12.9 0.0 2.0 2 0 0 2 2 2 0 Tetraspanin family TRAP_alpha PF03896.16 CDJ53368.1 - 0.019 14.2 0.6 0.019 14.2 0.6 3.8 3 1 1 4 4 4 0 Translocon-associated protein (TRAP), alpha subunit EST1 PF10374.9 CDJ53368.1 - 0.03 14.9 0.5 0.03 14.9 0.5 4.7 4 1 1 5 5 3 0 Telomerase activating protein Est1 Nucleoside_tran PF01733.18 CDJ53368.1 - 0.035 13.5 0.1 0.035 13.5 0.1 3.2 4 0 0 4 4 4 0 Nucleoside transporter MAP17 PF15807.5 CDJ53368.1 - 0.051 13.8 0.2 0.051 13.8 0.2 4.3 4 1 0 4 4 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 GRP PF07172.11 CDJ53368.1 - 0.088 13.5 0.2 0.088 13.5 0.2 3.6 3 1 1 4 4 2 0 Glycine rich protein family DUF5531 PF17671.1 CDJ53368.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5531) Stevor PF17410.2 CDJ53368.1 - 0.23 11.0 0.0 0.23 11.0 0.0 3.1 3 1 0 3 3 2 0 Subtelomeric Variable Open Reading frame O-antigen_lig PF13425.6 CDJ53368.1 - 0.52 9.0 0.0 0.52 9.0 0.0 2.7 3 0 0 3 3 3 0 O-antigen ligase like membrane protein Apt1 PF10351.9 CDJ53368.1 - 0.7 8.7 44.4 0.12 11.2 10.3 3.2 3 0 0 3 3 3 0 Golgi-body localisation protein domain 7tm_1 PF00001.21 CDJ53368.1 - 0.89 8.8 5.2 0.64 9.3 0.1 2.8 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) SARAF PF06682.12 CDJ53368.1 - 0.99 9.0 33.0 0.023 14.3 4.0 3.4 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Ecl1 PF12855.7 CDJ53368.1 - 1.8 9.7 50.2 3.6 8.7 7.3 3.3 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins AF-4 PF05110.13 CDJ53368.1 - 3.8 5.5 74.0 0.076 11.1 15.9 3.2 3 0 0 3 3 3 0 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ53369.1 - 0.00022 20.9 20.5 0.00022 20.9 20.5 3.0 2 1 1 3 3 2 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ53369.1 - 0.01 16.2 11.7 0.014 15.7 11.7 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SprA-related PF12118.8 CDJ53369.1 - 0.091 11.9 36.5 0.12 11.5 36.5 1.1 1 0 0 1 1 1 0 SprA-related family BAF1_ABF1 PF04684.13 CDJ53369.1 - 0.19 10.8 19.4 0.22 10.5 19.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4407 PF14362.6 CDJ53369.1 - 0.71 9.2 10.0 0.8 9.0 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC106 PF15794.5 CDJ53369.1 - 1.6 8.4 34.6 0.32 10.7 15.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 TFIIA PF03153.13 CDJ53369.1 - 1.7 8.6 27.8 2.4 8.0 27.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.9 CDJ53369.1 - 6.1 5.5 23.9 7.2 5.3 23.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF966 PF06136.13 CDJ53369.1 - 6.4 6.4 31.2 8 6.1 31.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Connexin PF00029.19 CDJ53369.1 - 9.6 5.9 8.6 3.1 7.5 4.9 1.8 2 0 0 2 2 2 0 Connexin LPP20 PF02169.16 CDJ53369.1 - 9.9 6.6 23.9 0.17 12.3 8.8 2.3 2 0 0 2 2 2 0 LPP20 lipoprotein RNA_pol_3_Rpc31 PF11705.8 CDJ53370.1 - 0.021 15.1 5.9 0.025 14.9 5.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_L11_N PF03946.14 CDJ53370.1 - 0.029 14.2 0.2 0.058 13.2 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain Paf1 PF03985.13 CDJ53370.1 - 0.1 11.5 7.4 0.11 11.5 7.4 1.0 1 0 0 1 1 1 0 Paf1 DUF4746 PF15928.5 CDJ53370.1 - 0.19 11.1 4.2 0.2 11.0 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) COPI_C PF06957.11 CDJ53370.1 - 0.26 10.0 5.4 0.28 9.9 5.4 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus SspB PF04386.13 CDJ53370.1 - 0.36 10.7 3.8 0.49 10.3 3.8 1.2 1 0 0 1 1 1 0 Stringent starvation protein B Nop14 PF04147.12 CDJ53370.1 - 0.39 8.9 5.5 0.43 8.7 5.5 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 CDJ53370.1 - 0.74 9.1 4.1 0.84 8.9 4.1 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 CDJ53370.1 - 3.9 5.7 5.2 4.4 5.5 5.2 1.0 1 0 0 1 1 1 0 CDC45-like protein TMEM119 PF15724.5 CDJ53370.1 - 7.8 6.5 13.3 2.6 8.0 10.6 1.5 1 1 1 2 2 2 0 TMEM119 family UNC-50 PF05216.13 CDJ53371.1 - 9.2e-30 103.9 0.2 1.2e-29 103.5 0.2 1.1 1 0 0 1 1 1 1 UNC-50 family PIG-F PF06699.11 CDJ53371.1 - 0.0046 17.1 1.1 0.0096 16.1 1.1 1.5 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F FAST_1 PF06743.15 CDJ53372.1 - 0.13 12.3 0.1 0.92 9.5 0.1 2.5 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 DUF3597 PF12200.8 CDJ53372.1 - 9.1 6.8 7.6 5.3 7.6 2.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) TFIIA PF03153.13 CDJ53374.1 - 0.11 12.5 11.2 0.13 12.3 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2057 PF09829.9 CDJ53374.1 - 2.1 8.5 14.2 0.35 11.0 3.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) PPP4R2 PF09184.11 CDJ53374.1 - 2.9 7.4 8.7 3.6 7.1 8.7 1.1 1 0 0 1 1 1 0 PPP4R2 DUF4667 PF15700.5 CDJ53375.1 - 1 9.4 22.8 0.049 13.7 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) AF-4 PF05110.13 CDJ53375.1 - 2.2 6.3 27.1 0.6 8.1 7.5 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein RskA PF10099.9 CDJ53376.1 - 4.9e-11 43.2 27.0 3.5e-05 24.2 0.0 4.2 1 1 2 4 4 4 2 Anti-sigma-K factor rskA Trp_oprn_chp PF09534.10 CDJ53376.1 - 0.00013 21.8 3.5 0.00013 21.8 3.5 3.8 3 1 0 3 3 3 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ribosomal_60s PF00428.19 CDJ53376.1 - 1.8 9.2 40.2 1.3 9.6 12.1 3.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein LAP1C PF05609.12 CDJ53376.1 - 5.7 5.9 45.4 12 4.9 45.4 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Helicase_C_2 PF13307.6 CDJ53377.1 - 2.9e-22 79.6 7.8 2.9e-22 79.6 7.8 4.9 4 1 0 4 4 4 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDJ53377.1 - 2.2e-06 27.4 0.0 2.2e-06 27.4 0.0 4.7 6 0 0 6 6 6 1 DEAD_2 N6_N4_Mtase PF01555.18 CDJ53377.1 - 0.0036 17.0 0.9 49 3.5 0.0 4.4 4 2 0 4 4 4 0 DNA methylase SAPS PF04499.15 CDJ53377.1 - 0.46 9.2 0.0 0.46 9.2 0.0 5.5 3 2 1 4 4 4 0 SIT4 phosphatase-associated protein Shadoo PF14999.6 CDJ53379.1 - 1.4 9.0 16.2 4.1 7.5 4.0 2.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective RT_RNaseH PF17917.1 CDJ53380.1 - 8.9e-23 80.6 0.0 1.8e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ53380.1 - 5.4e-15 55.3 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ53380.1 - 3.2e-14 53.0 0.0 5.3e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDJ53380.1 - 2.5e-05 24.8 0.0 5.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ53380.1 - 0.00023 21.6 0.0 0.00048 20.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ53380.1 - 0.057 13.2 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease PBP1_TM PF14812.6 CDJ53385.1 - 0.19 12.1 10.0 0.22 11.9 10.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Connexin PF00029.19 CDJ53385.1 - 0.41 10.4 19.6 0.44 10.3 19.6 1.0 1 0 0 1 1 1 0 Connexin TFB6 PF17110.5 CDJ53385.1 - 0.43 10.3 11.8 0.44 10.3 11.8 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NARP1 PF12569.8 CDJ53385.1 - 0.71 8.7 21.4 0.72 8.7 21.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1764 PF08576.10 CDJ53385.1 - 0.78 10.7 17.5 0.94 10.4 17.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3464 PF11947.8 CDJ53385.1 - 0.87 9.3 19.9 1.3 8.8 19.9 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Rtf2 PF04641.12 CDJ53385.1 - 0.95 8.8 18.6 0.99 8.7 18.6 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger FAM176 PF14851.6 CDJ53385.1 - 1.1 8.9 14.9 1.2 8.7 14.9 1.1 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.12 CDJ53385.1 - 1.1 9.0 23.0 1.2 8.9 23.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Afi1 PF07792.12 CDJ53385.1 - 1.3 9.5 18.8 1.5 9.3 18.8 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking AIF_C PF14721.6 CDJ53385.1 - 1.3 9.3 15.6 1.6 9.1 15.6 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RNA_pol_Rpc4 PF05132.14 CDJ53385.1 - 1.4 9.3 17.9 1.5 9.2 17.9 1.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2828 PF11443.8 CDJ53385.1 - 1.5 6.8 21.7 1.6 6.8 21.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CPSF100_C PF13299.6 CDJ53385.1 - 1.8 8.8 17.6 1.8 8.7 17.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF5308 PF17233.2 CDJ53385.1 - 1.9 8.7 15.9 2 8.6 15.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) ArsP_2 PF11449.8 CDJ53385.1 - 2.4 7.3 6.2 2.5 7.2 6.2 1.1 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter DUF5523 PF17661.1 CDJ53385.1 - 2.4 7.8 21.2 2.5 7.7 21.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RPN2_C PF18004.1 CDJ53385.1 - 2.5 8.0 20.2 2.6 8.0 20.2 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4050 PF13259.6 CDJ53385.1 - 2.5 8.4 17.6 2.7 8.3 17.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF3306 PF11748.8 CDJ53385.1 - 2.6 8.9 19.1 3 8.7 19.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) FAM60A PF15396.6 CDJ53385.1 - 2.9 7.8 17.2 3 7.8 17.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Gti1_Pac2 PF09729.9 CDJ53385.1 - 3.4 7.7 18.9 3.5 7.7 18.9 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family EFTUD2 PF16004.5 CDJ53385.1 - 3.4 8.3 20.6 4.2 8.0 20.6 1.1 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus SpoIIP PF07454.11 CDJ53385.1 - 4 6.8 24.1 4.2 6.8 24.1 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Nucleoside_tran PF01733.18 CDJ53385.1 - 4.6 6.5 11.9 4.9 6.4 11.9 1.0 1 0 0 1 1 1 0 Nucleoside transporter Tim54 PF11711.8 CDJ53385.1 - 4.9 5.8 20.7 5.1 5.8 20.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EOS1 PF12326.8 CDJ53385.1 - 5.6 6.9 14.2 6 6.8 14.2 1.1 1 0 0 1 1 1 0 N-glycosylation protein NPR3 PF03666.13 CDJ53385.1 - 5.6 5.6 22.2 6 5.5 22.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RP-C_C PF11800.8 CDJ53385.1 - 6 6.9 19.7 6.6 6.8 19.7 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF913 PF06025.12 CDJ53385.1 - 6.3 5.7 14.9 6.2 5.7 14.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Kei1 PF08552.11 CDJ53385.1 - 6.8 6.5 14.5 6.8 6.5 14.5 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 PRC2_HTH_1 PF18118.1 CDJ53385.1 - 6.8 7.6 15.5 8.7 7.2 15.5 1.3 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain MMM1 PF10296.9 CDJ53385.1 - 6.9 5.6 14.6 6.9 5.6 14.6 1.0 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 MMU163 PF17119.5 CDJ53385.1 - 7.3 5.7 11.1 8.4 5.5 11.1 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis PPL5 PF18168.1 CDJ53385.1 - 8.6 5.6 15.8 9 5.5 15.8 1.0 1 0 0 1 1 1 0 Prim-pol family 5 CLN3 PF02487.17 CDJ53385.1 - 9 5.2 18.6 9 5.2 18.6 1.0 1 0 0 1 1 1 0 CLN3 protein eIF3_subunit PF08597.10 CDJ53385.1 - 9.5 6.1 25.1 9.7 6.0 25.1 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Apt1 PF10351.9 CDJ53386.1 - 7.2 5.4 8.9 7.5 5.3 8.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ53386.1 - 8.6 4.8 13.3 9.7 4.6 13.3 1.1 1 0 0 1 1 1 0 Macoilin family Dehydrin PF00257.19 CDJ53387.1 - 0.078 13.5 11.8 0.077 13.5 8.4 2.1 2 0 0 2 2 2 0 Dehydrin DUF1635 PF07795.11 CDJ53387.1 - 0.22 11.4 2.3 0.11 12.3 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF4131 PF13567.6 CDJ53387.1 - 2.1 8.0 6.9 13 5.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) YbgS PF13985.6 CDJ53387.1 - 5.4 7.3 15.4 5.3 7.3 8.7 2.2 2 0 0 2 2 2 0 YbgS-like protein SR-25 PF10500.9 CDJ53387.1 - 5.6 6.5 21.2 9.2 5.8 21.2 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CPSF100_C PF13299.6 CDJ53388.1 - 0.45 10.7 18.1 0.52 10.5 18.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MMU163 PF17119.5 CDJ53388.1 - 1.6 7.8 9.4 1.9 7.6 9.4 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF5523 PF17661.1 CDJ53388.1 - 1.8 8.2 22.0 1.9 8.1 22.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RNA_pol_Rpc4 PF05132.14 CDJ53388.1 - 2 8.8 20.4 2.3 8.6 20.4 1.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3306 PF11748.8 CDJ53388.1 - 4.1 8.3 16.9 6.4 7.7 16.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Presenilin PF01080.17 CDJ53388.1 - 4.2 6.0 25.9 4.4 6.0 25.9 1.0 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 CDJ53388.1 - 4.5 6.2 16.9 4.6 6.2 16.9 1.0 1 0 0 1 1 1 0 CLN3 protein DUF1764 PF08576.10 CDJ53388.1 - 4.7 8.2 17.5 7 7.6 17.5 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) MDM31_MDM32 PF08118.11 CDJ53388.1 - 4.9 5.7 12.7 5.3 5.6 12.7 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Tim54 PF11711.8 CDJ53388.1 - 5.2 5.7 19.7 5.4 5.7 19.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SID-1_RNA_chan PF13965.6 CDJ53388.1 - 5.4 5.3 13.6 5.7 5.2 13.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NARP1 PF12569.8 CDJ53388.1 - 6 5.6 19.7 6.4 5.6 19.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EOS1 PF12326.8 CDJ53388.1 - 6.1 6.7 11.5 7 6.5 11.5 1.2 1 0 0 1 1 1 0 N-glycosylation protein Endostatin PF06482.11 CDJ53388.1 - 6.3 6.2 17.9 6.5 6.1 17.9 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PPL5 PF18168.1 CDJ53388.1 - 6.5 6.0 16.6 6.8 5.9 16.6 1.0 1 0 0 1 1 1 0 Prim-pol family 5 DDRGK PF09756.9 CDJ53388.1 - 7 6.2 32.2 7.3 6.1 32.2 1.0 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.12 CDJ53388.1 - 7.6 6.3 24.0 8.1 6.2 24.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CDJ53388.1 - 8.1 6.5 18.8 9.1 6.4 18.8 1.1 1 0 0 1 1 1 0 DDHD domain Pex14_N PF04695.13 CDJ53388.1 - 9.1 6.9 28.7 12 6.5 28.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pal1 PF08316.11 CDJ53388.1 - 9.3 7.0 12.2 9.8 6.9 12.2 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF4471 PF14740.6 CDJ53388.1 - 9.5 5.3 14.8 10 5.2 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) TFIIA PF03153.13 CDJ53389.1 - 0.013 15.5 23.2 0.013 15.6 23.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ53389.1 - 0.4 10.7 6.9 0.39 10.7 6.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 CDJ53389.1 - 0.65 10.1 12.6 0.79 9.8 12.6 1.1 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.6 CDJ53389.1 - 4.1 7.4 12.4 5.1 7.0 12.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Spt20 PF12090.8 CDJ53389.1 - 4.4 6.8 39.4 5.9 6.4 39.4 1.1 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ53389.1 - 4.8 5.8 20.9 5.6 5.6 20.9 1.0 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ53389.1 - 4.9 6.0 23.3 6.3 5.7 23.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 CDJ53389.1 - 4.9 6.5 19.6 5.6 6.3 19.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDJ53389.1 - 5.1 6.8 20.2 5.7 6.7 20.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3408 PF11888.8 CDJ53389.1 - 5.5 7.1 18.9 7.4 6.7 18.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Peptidase_U57 PF05582.12 CDJ53389.1 - 6.5 5.9 11.2 7.6 5.7 11.2 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Suf PF05843.14 CDJ53389.1 - 6.9 6.6 14.5 9.8 6.1 14.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 CDJ53389.1 - 7.9 7.5 21.3 12 6.9 21.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MITF_TFEB_C_3_N PF15951.5 CDJ53390.1 - 0.0046 17.6 9.8 0.0046 17.6 9.8 8.3 7 1 2 9 9 9 1 MITF/TFEB/TFEC/TFE3 N-terminus RRM_1 PF00076.22 CDJ53390.1 - 0.041 13.7 0.0 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OCRE PF17780.1 CDJ53390.1 - 0.075 13.1 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 OCRE domain POX PF07526.11 CDJ53390.1 - 0.7 10.5 0.0 0.7 10.5 0.0 7.9 7 1 0 7 7 7 0 Associated with HOX Lar_restr_allev PF14354.6 CDJ53390.1 - 1.4 9.3 4.7 1.6 9.2 1.7 2.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF2514 PF10721.9 CDJ53391.1 - 0.0041 17.2 7.6 0.0041 17.2 7.6 3.8 3 2 0 3 3 1 1 Protein of unknown function (DUF2514) PRCC PF10253.9 CDJ53391.1 - 0.0064 17.3 1.8 0.0064 17.3 1.8 2.1 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting TctB PF07331.11 CDJ53391.1 - 0.04 14.2 0.4 0.078 13.2 0.4 1.5 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family POX PF07526.11 CDJ53391.1 - 0.82 10.2 16.1 0.12 13.0 8.9 2.2 2 0 0 2 2 2 0 Associated with HOX DUF572 PF04502.13 CDJ53391.1 - 0.99 9.0 18.4 1.7 8.2 18.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF5531 PF17671.1 CDJ53391.1 - 1.6 8.6 6.4 0.8 9.6 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5531) DUF4381 PF14316.6 CDJ53391.1 - 1.9 8.7 22.9 0.035 14.3 5.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) FAM60A PF15396.6 CDJ53391.1 - 2.1 8.3 8.4 11 5.9 8.0 1.9 2 0 0 2 2 2 0 Protein Family FAM60A CHDCT2 PF08074.11 CDJ53391.1 - 3.6 7.7 11.7 0.18 12.0 4.0 2.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain UPF0242 PF06785.11 CDJ53391.1 - 4.6 7.3 22.7 4.6 7.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus WDCP PF15390.6 CDJ53391.1 - 5.2 5.3 12.2 5.6 5.2 11.6 1.2 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family CAML PF14963.6 CDJ53391.1 - 7.5 6.6 9.4 1.5 8.9 5.4 1.7 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Roughex PF06020.11 CDJ53392.1 - 0.052 12.7 3.6 0.089 11.9 3.6 1.4 1 1 0 1 1 1 0 Drosophila roughex protein Apt1 PF10351.9 CDJ53392.1 - 0.078 11.8 8.3 0.078 11.8 8.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 CDJ53392.1 - 0.12 11.8 3.1 0.14 11.5 3.1 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Menin PF05053.13 CDJ53392.1 - 0.13 10.6 8.4 0.15 10.4 8.4 1.0 1 0 0 1 1 1 0 Menin SPX PF03105.19 CDJ53392.1 - 0.39 10.6 11.3 0.42 10.5 11.3 1.0 1 0 0 1 1 1 0 SPX domain Lin-8 PF03353.15 CDJ53392.1 - 1.6 8.3 3.2 1.9 8.0 3.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF515 PF04415.12 CDJ53392.1 - 5.9 5.2 23.2 9.4 4.5 23.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Miga PF10265.9 CDJ53392.1 - 6.1 5.7 9.1 6.5 5.6 9.1 1.2 1 0 0 1 1 1 0 Mitoguardin DUF2052 PF09747.9 CDJ53393.1 - 0.18 11.9 26.0 0.69 10.0 26.0 2.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) ASD2 PF08687.11 CDJ53393.1 - 0.39 10.2 36.4 0.013 15.0 28.5 2.3 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 SLC12 PF03522.15 CDJ53393.1 - 1.4 7.8 22.7 2.7 6.9 22.7 1.5 1 0 0 1 1 1 0 Solute carrier family 12 BAF1_ABF1 PF04684.13 CDJ53393.1 - 2 7.4 21.8 5.1 6.0 21.8 1.7 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDK5_activator PF03261.15 CDJ53393.1 - 4.8 6.6 17.1 8.5 5.8 17.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Ndc1_Nup PF09531.10 CDJ53393.1 - 7.8 5.1 30.4 17 3.9 30.4 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TRAP_alpha PF03896.16 CDJ53394.1 - 0.27 10.4 4.2 0.64 9.2 4.2 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SUIM_assoc PF16619.5 CDJ53394.1 - 0.34 11.0 0.0 0.34 11.0 0.0 7.8 5 3 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 DUF3292 PF11696.8 CDJ53394.1 - 0.65 8.3 4.8 1.7 6.9 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) CDC45 PF02724.14 CDJ53394.1 - 1.9 6.7 15.8 0.03 12.6 5.6 2.2 2 0 0 2 2 2 0 CDC45-like protein SpoIIP PF07454.11 CDJ53394.1 - 3.4 7.0 10.2 0.061 12.8 2.9 1.8 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 CDJ53394.1 - 3.6 7.7 14.8 0.052 13.7 0.4 3.2 3 0 0 3 3 3 0 DDHD domain Terminase_6C PF17289.2 CDJ53395.1 - 0.031 14.4 0.1 0.079 13.1 0.1 1.6 1 0 0 1 1 1 0 Terminase RNaseH-like domain Myb_DNA-bind_7 PF15963.5 CDJ53396.1 - 6.6e-21 74.0 0.1 6.6e-21 74.0 0.1 4.2 4 0 0 4 4 4 1 Myb DNA-binding like HMG_box PF00505.19 CDJ53396.1 - 1e-06 29.0 7.1 5.8e-05 23.4 0.5 3.6 3 0 0 3 3 3 2 HMG (high mobility group) box Myb_DNA-binding PF00249.31 CDJ53396.1 - 0.067 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Dynein_light PF01221.18 CDJ53397.1 - 3.1 8.2 4.3 15 6.0 4.3 2.2 1 0 0 1 1 1 0 Dynein light chain type 1 PA PF02225.22 CDJ53398.1 - 5.2e-06 26.4 0.1 1.1e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 PA domain SUIM_assoc PF16619.5 CDJ53398.1 - 0.0032 17.5 2.8 0.0032 17.5 2.8 2.0 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 60KD_IMP PF02096.20 CDJ53398.1 - 0.0045 16.9 0.5 0.0045 16.9 0.5 1.8 2 0 0 2 2 2 1 60Kd inner membrane protein Spt20 PF12090.8 CDJ53398.1 - 0.015 14.9 2.5 0.023 14.3 2.5 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ53398.1 - 0.049 12.6 0.4 0.068 12.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF5345 PF17280.2 CDJ53398.1 - 0.16 11.9 2.8 0.46 10.5 2.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5345) 7TM_GPCR_Srv PF10323.9 CDJ53398.1 - 0.17 11.3 2.3 3.1 7.1 0.4 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv PAT1 PF09770.9 CDJ53399.1 - 1.1 7.5 23.4 1.6 6.9 23.4 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Citrate_synt PF00285.21 CDJ53400.1 - 3.1e-88 296.3 0.0 3.6e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain WD40 PF00400.32 CDJ53401.1 - 7.2e-45 150.1 29.2 1.6e-09 38.2 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ53401.1 - 1.5e-10 41.3 2.2 0.39 11.1 0.0 4.9 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDJ53401.1 - 5.3e-08 32.5 0.0 7.6e-05 22.2 0.0 2.6 2 1 1 3 3 3 3 WD40-like domain PQQ_3 PF13570.6 CDJ53401.1 - 0.00087 19.7 0.4 0.14 12.7 0.0 3.6 3 1 0 3 3 3 1 PQQ-like domain Nup160 PF11715.8 CDJ53401.1 - 0.01 14.5 15.9 0.076 11.6 0.4 4.8 1 1 4 5 5 5 0 Nucleoporin Nup120/160 Adeno_terminal PF02459.15 CDJ53401.1 - 0.082 11.3 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein tRNA-synt_1 PF00133.22 CDJ53402.1 - 4.8e-65 220.0 0.0 8.3e-45 153.1 0.0 5.2 4 1 0 4 4 4 4 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ53402.1 - 1.4e-19 70.5 0.0 2.7e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ53402.1 - 1.1e-08 34.3 0.0 1.9e-06 26.9 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) DUF2012 PF09430.10 CDJ53403.1 - 1e-10 41.8 0.0 1.5e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) OTU PF02338.19 CDJ53404.1 - 3.3e-09 37.3 0.0 1.2e-08 35.5 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDJ53404.1 - 0.0026 17.3 0.2 0.068 12.6 0.1 2.2 1 1 1 2 2 2 1 Peptidase C65 Otubain VWA PF00092.28 CDJ53405.1 - 6e-33 114.5 0.0 8.1e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 CDJ53405.1 - 3.7e-24 84.7 66.5 1.1e-08 35.1 1.3 7.5 6 2 0 6 6 6 6 Thrombospondin type 1 domain VWA_2 PF13519.6 CDJ53405.1 - 2.1e-13 50.8 0.0 3.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CDJ53405.1 - 0.00025 21.0 0.0 0.00036 20.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain FKS1_dom1 PF14288.6 CDJ53406.1 - 0.1 12.9 3.1 0.22 11.8 3.1 1.5 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 PP1_bind PF15276.6 CDJ53406.1 - 0.21 11.9 0.0 0.21 11.9 0.0 3.2 3 1 1 4 4 4 0 Protein phosphatase 1 binding DUF3504 PF12012.8 CDJ53406.1 - 5.2 6.9 13.7 0.055 13.4 2.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3504) Hid1 PF12722.7 CDJ53406.1 - 5.9 4.9 14.6 6.6 4.7 14.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SARAF PF06682.12 CDJ53406.1 - 8.1 6.0 22.3 14 5.3 22.3 1.5 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Pyr_redox_2 PF07992.14 CDJ53407.1 - 1.3e-32 113.3 0.1 7.3e-20 71.4 0.0 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ53407.1 - 6.7e-27 93.9 1.7 8.4e-27 93.6 0.1 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ53407.1 - 2.6e-13 50.3 0.0 8.3e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CDJ53407.1 - 1e-05 25.5 0.9 0.00011 22.2 0.0 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CDJ53407.1 - 0.0011 18.3 1.1 0.023 14.1 0.0 2.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 CDJ53407.1 - 0.0023 17.1 7.8 0.02 14.0 0.8 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 CDJ53407.1 - 0.0097 15.5 0.0 0.0097 15.5 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 CDJ53407.1 - 0.014 15.6 0.4 0.014 15.6 0.4 3.7 4 0 0 4 4 3 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 CDJ53407.1 - 0.018 14.3 13.2 0.33 10.2 0.0 2.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 CDJ53407.1 - 0.035 13.2 15.4 0.68 8.9 4.8 3.7 3 0 0 3 3 3 0 FAD binding domain V_ATPase_I PF01496.19 CDJ53407.1 - 0.14 10.1 1.9 0.2 9.6 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM51 PF15345.6 CDJ53407.1 - 0.18 11.6 2.4 0.73 9.6 0.7 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 MSC PF09402.10 CDJ53407.1 - 0.29 10.6 1.3 0.44 9.9 1.3 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain ABC2_membrane_2 PF12679.7 CDJ53407.1 - 0.41 9.9 5.2 0.04 13.2 0.5 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein EphA2_TM PF14575.6 CDJ53407.1 - 1.4 9.8 4.4 4.4 8.2 4.4 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UPF0560 PF10577.9 CDJ53407.1 - 4.7 5.6 9.1 7.2 5.0 9.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Spt20 PF12090.8 CDJ53408.1 - 6.7e-05 22.6 9.4 6.7e-05 22.6 9.4 1.4 2 0 0 2 2 2 1 Spt20 family TFIIA PF03153.13 CDJ53408.1 - 0.6 10.0 23.1 1.2 9.1 23.0 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ53408.1 - 0.74 10.1 26.5 0.13 12.6 12.3 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Med15 PF09606.10 CDJ53408.1 - 0.9 8.1 21.2 0.028 13.1 12.5 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MITF_TFEB_C_3_N PF15951.5 CDJ53408.1 - 1.1 9.8 29.4 2.7 8.6 19.1 2.7 2 1 1 3 3 3 0 MITF/TFEB/TFEC/TFE3 N-terminus Kinesin_assoc PF16183.5 CDJ53408.1 - 1.4 9.1 4.7 0.85 9.7 2.9 1.6 1 1 1 2 2 2 0 Kinesin-associated SR-25 PF10500.9 CDJ53409.1 - 0.0066 16.1 8.1 0.0066 16.1 8.1 5.0 3 2 0 3 3 3 1 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ53409.1 - 0.077 12.9 38.7 16 5.3 38.7 2.2 1 1 0 1 1 1 0 SPX domain EPL1 PF10513.9 CDJ53409.1 - 6.9 7.0 23.2 0.94 9.9 0.3 3.2 2 1 1 3 3 3 0 Enhancer of polycomb-like Hamartin PF04388.12 CDJ53410.1 - 0.34 9.5 40.1 0.44 9.2 40.1 1.1 1 0 0 1 1 1 0 Hamartin protein SART-1 PF03343.13 CDJ53410.1 - 0.81 8.2 36.7 1.2 7.5 36.7 1.2 1 0 0 1 1 1 0 SART-1 family SMYLE_N PF18615.1 CDJ53410.1 - 3 7.3 25.1 4.7 6.7 25.1 1.4 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain cEGF PF12662.7 CDJ53411.1 - 2.5e-12 46.5 20.8 1.1e-07 31.7 0.1 5.3 5 0 0 5 5 5 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDJ53411.1 - 5.5e-12 45.7 18.8 1.3e-06 28.5 3.4 2.9 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CDJ53411.1 - 8.3e-09 35.5 25.0 1.4e-05 25.2 3.5 4.3 4 0 0 4 4 4 3 Calcium-binding EGF domain Shisa PF13908.6 CDJ53411.1 - 0.0013 19.0 2.6 0.0013 19.0 2.6 11.4 5 3 5 11 11 11 1 Wnt and FGF inhibitory regulator EGF_3 PF12947.7 CDJ53411.1 - 0.0017 18.5 23.9 0.018 15.3 0.2 3.9 3 0 0 3 3 3 2 EGF domain hEGF PF12661.7 CDJ53411.1 - 0.0058 17.2 1.8 0.0058 17.2 1.8 3.4 4 0 0 4 4 4 1 Human growth factor-like EGF EGF PF00008.27 CDJ53411.1 - 0.0099 16.2 0.9 0.0099 16.2 0.9 3.6 3 0 0 3 3 3 2 EGF-like domain Pex14_N PF04695.13 CDJ53411.1 - 0.016 15.9 6.0 0.016 15.9 6.0 13.5 5 2 5 11 11 11 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 CDJ53411.1 - 0.043 14.8 0.7 0.043 14.8 0.7 13.9 9 3 0 10 10 10 0 Domain of unknown function (DUF4834) Plasmod_Pvs28 PF06247.11 CDJ53411.1 - 0.63 10.4 3.5 1 9.7 0.3 2.6 2 0 0 2 2 2 0 Pvs28 EGF domain HSP90 PF00183.18 CDJ53412.1 - 4.5e-123 411.9 10.0 4.7e-88 296.3 0.0 3.3 4 0 0 4 4 4 2 Hsp90 protein HATPase_c_3 PF13589.6 CDJ53412.1 - 1e-09 38.3 0.1 2.8e-09 36.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ53412.1 - 9e-08 32.6 0.1 2.6e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_60s PF00428.19 CDJ53412.1 - 0.0077 16.8 2.6 0.0077 16.8 2.6 5.5 5 0 0 5 5 5 2 60s Acidic ribosomal protein RskA PF10099.9 CDJ53412.1 - 0.015 15.6 5.4 0.015 15.6 5.4 6.4 4 3 2 6 6 6 0 Anti-sigma-K factor rskA ASFV_J13L PF05568.11 CDJ53412.1 - 0.047 13.5 0.5 0.047 13.5 0.5 4.0 3 1 1 4 4 4 0 African swine fever virus J13L protein Adaptin_binding PF10199.9 CDJ53413.1 - 0.0058 17.2 2.3 0.0058 17.2 2.3 6.3 3 3 1 4 4 4 1 Alpha and gamma adaptin binding protein p34 RskA PF10099.9 CDJ53414.1 - 0.0097 16.2 0.0 0.0097 16.2 0.0 2.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA EVI2A PF05399.11 CDJ53414.1 - 0.0098 15.5 0.6 0.013 15.1 0.0 1.4 2 0 0 2 2 2 1 Ectropic viral integration site 2A protein (EVI2A) DUF1645 PF07816.11 CDJ53414.1 - 0.016 15.8 3.8 0.02 15.4 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Hid1 PF12722.7 CDJ53414.1 - 0.034 12.3 9.1 0.046 11.9 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ERG4_ERG24 PF01222.17 CDJ53414.1 - 0.035 12.9 0.3 0.037 12.8 0.3 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family PBP1_TM PF14812.6 CDJ53414.1 - 0.037 14.4 0.2 0.037 14.4 0.2 2.9 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SAPS PF04499.15 CDJ53414.1 - 0.043 12.6 8.3 0.93 8.2 0.1 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein FGF-BP1 PF06473.12 CDJ53414.1 - 0.047 13.5 18.9 0.069 13.0 8.5 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Suf PF05843.14 CDJ53414.1 - 0.34 10.9 25.0 0.37 10.7 14.3 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4366 PF14283.6 CDJ53414.1 - 0.49 10.4 8.8 2.8 8.0 6.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) RR_TM4-6 PF06459.12 CDJ53414.1 - 0.87 9.4 15.7 0.096 12.5 8.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 CDJ53414.1 - 0.94 8.6 5.6 1.6 7.9 5.6 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter LIN37 PF15306.6 CDJ53414.1 - 1.1 9.4 20.8 0.085 13.1 14.1 1.9 2 0 0 2 2 2 0 LIN37 GET2 PF08690.10 CDJ53414.1 - 1.7 8.3 20.9 0.022 14.4 8.5 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 ALMT PF11744.8 CDJ53414.1 - 1.9 7.3 8.3 1.1 8.0 5.0 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter Lin-8 PF03353.15 CDJ53414.1 - 4.5 6.8 21.8 0.061 12.9 10.1 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF2956 PF11169.8 CDJ53414.1 - 8.6 6.6 30.2 0.11 12.6 3.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2956) tRNA-synt_His PF13393.6 CDJ53415.1 - 2.3e-40 138.8 0.1 2.3e-40 138.8 0.1 5.2 5 1 2 7 7 3 1 Histidyl-tRNA synthetase TFIIA PF03153.13 CDJ53415.1 - 0.00021 21.4 76.3 0.0044 17.1 16.0 3.7 4 0 0 4 4 4 3 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ53415.1 - 0.00023 20.8 58.1 0.015 14.9 14.2 3.6 3 0 0 3 3 3 3 Spt20 family tRNA-synt_2b PF00587.25 CDJ53415.1 - 0.057 13.4 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 CDJ53415.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF2722 PF10846.8 CDJ53415.1 - 0.37 9.7 54.9 0.059 12.3 12.8 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) Ecl1 PF12855.7 CDJ53415.1 - 1.3 10.2 37.8 0.062 14.5 10.7 4.3 4 0 0 4 4 4 0 ECL1/2/3 zinc binding proteins AAT PF03417.16 CDJ53415.1 - 1.4 8.6 13.3 0.02 14.6 1.3 3.2 3 0 0 3 3 3 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Folate_carrier PF01770.18 CDJ53415.1 - 2.1 7.0 6.7 4.7 5.8 0.4 2.5 2 0 0 2 2 2 0 Reduced folate carrier DUF5327 PF17261.2 CDJ53415.1 - 3.3 8.5 27.4 2.2 9.1 5.7 4.5 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Peptidase_S49_N PF08496.10 CDJ53415.1 - 3.6 7.6 16.8 1.8 8.7 3.3 3.5 3 0 0 3 3 3 0 Peptidase family S49 N-terminal SID-1_RNA_chan PF13965.6 CDJ53415.1 - 4.4 5.6 5.7 0.95 7.8 1.4 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 MAS20 PF02064.15 CDJ53415.1 - 5 7.2 22.3 1.1 9.4 3.3 4.2 3 0 0 3 3 3 0 MAS20 protein import receptor tRNA_lig_CPD PF08302.11 CDJ53415.1 - 5.1 6.5 18.1 0.069 12.6 1.0 3.1 3 0 0 3 3 3 0 Fungal tRNA ligase phosphodiesterase domain RAB3GAP2_N PF14655.6 CDJ53415.1 - 6.8 5.8 21.2 1.9 7.7 2.8 3.5 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.14 CDJ53415.1 - 7.9 6.4 30.2 1.4 8.8 6.3 3.4 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CDJ53416.1 - 0.0055 16.3 27.3 0.018 14.6 15.2 2.1 2 0 0 2 2 2 2 Spt20 family NYAP_N PF15439.6 CDJ53416.1 - 0.011 15.0 7.5 0.011 15.0 7.5 2.1 2 0 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter ANAPC_CDC26 PF10471.9 CDJ53416.1 - 0.042 14.7 30.7 0.05 14.4 13.4 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 EPL1 PF10513.9 CDJ53416.1 - 0.083 13.3 6.0 0.15 12.4 1.1 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF2722 PF10846.8 CDJ53416.1 - 0.096 11.6 18.6 0.014 14.4 10.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ53416.1 - 0.17 11.8 41.4 0.23 11.4 41.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ53416.1 - 0.9 9.4 9.3 1.4 8.8 9.3 1.3 1 0 0 1 1 1 0 SPX domain DUF3371 PF11851.8 CDJ53416.1 - 1.2 10.2 17.5 0.048 14.8 6.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3371) MPM1 PF17234.2 CDJ53416.1 - 1.3 9.3 8.1 0.38 11.0 3.1 2.0 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DAG_kinase_N PF14513.6 CDJ53416.1 - 3 8.0 8.8 0.84 9.8 2.3 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus BRF1 PF07741.13 CDJ53416.1 - 3.7 8.0 10.9 1.7 9.0 3.2 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Apc15p PF05841.11 CDJ53416.1 - 3.9 8.3 15.1 2.8 8.8 5.6 2.4 2 0 0 2 2 2 0 Apc15p protein XAP5 PF04921.14 CDJ53416.1 - 5.3 6.8 6.9 0.93 9.3 1.4 2.0 2 0 0 2 2 2 0 XAP5, circadian clock regulator Dehydrin PF00257.19 CDJ53420.1 - 0.0054 17.3 0.9 0.0054 17.3 0.9 14.6 8 5 4 12 12 12 2 Dehydrin DUF4667 PF15700.5 CDJ53420.1 - 0.0064 16.6 2.3 0.0064 16.6 2.3 8.6 6 2 2 8 8 8 1 Domain of unknown function (DUF4667) RskA PF10099.9 CDJ53420.1 - 0.009 16.3 8.8 0.009 16.3 8.8 16.2 5 3 9 15 15 15 2 Anti-sigma-K factor rskA RskA PF10099.9 CDJ53421.1 - 0.004 17.5 13.5 0.004 17.5 13.5 11.4 4 3 3 8 8 8 2 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ53421.1 - 0.007 15.4 0.0 0.007 15.4 0.0 8.9 6 3 2 8 8 8 1 Protein of unknown function (DUF2722) GEMIN8 PF15348.6 CDJ53422.1 - 1.4 9.2 28.4 0.094 13.0 14.3 2.5 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Ecl1 PF12855.7 CDJ53422.1 - 3.8 8.6 34.0 4.6 8.4 12.3 2.9 2 1 0 2 2 2 0 ECL1/2/3 zinc binding proteins Jnk-SapK_ap_N PF09744.9 CDJ53423.1 - 0.21 11.8 40.5 0.017 15.4 28.1 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 PAT1 PF09770.9 CDJ53424.1 - 0.43 8.8 53.3 0.53 8.5 53.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.6 CDJ53424.1 - 1.2 7.5 5.9 1.3 7.3 5.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDK5_activator PF03261.15 CDJ53424.1 - 9.6 5.6 22.5 14 5.1 22.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Nuf2 PF03800.14 CDJ53425.1 - 0.00017 21.7 0.9 0.00027 21.1 0.0 1.9 2 0 0 2 2 2 1 Nuf2 family Endonuc-dimeris PF09124.10 CDJ53425.1 - 0.043 14.0 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation TFIIF_alpha PF05793.12 CDJ53425.1 - 0.16 10.6 0.7 0.27 9.8 0.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RAP1 PF07218.11 CDJ53425.1 - 0.54 8.5 3.2 0.65 8.2 3.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TFIIA PF03153.13 CDJ53426.1 - 0.012 15.6 39.3 0.015 15.3 39.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ53426.1 - 0.044 12.8 18.5 0.046 12.7 18.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.6 CDJ53426.1 - 0.044 11.7 31.7 0.045 11.7 31.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DDHD PF02862.17 CDJ53426.1 - 0.064 13.4 11.9 0.063 13.4 11.9 1.2 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 CDJ53426.1 - 0.075 11.0 12.1 0.067 11.1 12.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Band_3_cyto PF07565.13 CDJ53426.1 - 0.15 11.9 11.6 0.14 11.9 11.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ53426.1 - 0.16 10.7 17.1 0.17 10.6 17.1 1.1 1 0 0 1 1 1 0 Presenilin DUF702 PF05142.12 CDJ53426.1 - 0.29 11.6 14.6 0.43 11.1 14.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF853 PF05872.12 CDJ53426.1 - 0.38 9.3 9.6 0.39 9.2 9.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Hydin_ADK PF17213.3 CDJ53426.1 - 0.66 10.2 9.8 0.86 9.8 9.8 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PA26 PF04636.13 CDJ53426.1 - 0.7 8.7 11.4 0.73 8.7 11.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.7 CDJ53426.1 - 0.71 7.9 13.5 0.67 8.0 13.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Exonuc_VII_L PF02601.15 CDJ53426.1 - 0.73 9.3 14.6 0.67 9.5 14.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4746 PF15928.5 CDJ53426.1 - 0.74 9.2 12.9 0.83 9.0 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CBP_BcsG PF11658.8 CDJ53426.1 - 0.81 8.0 12.1 0.94 7.8 12.1 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF2828 PF11443.8 CDJ53426.1 - 0.82 7.7 14.2 0.88 7.6 14.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PepSY_TM PF03929.16 CDJ53426.1 - 0.92 9.1 9.2 1.1 8.8 9.2 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Otopetrin PF03189.13 CDJ53426.1 - 1.1 8.1 5.7 0.94 8.2 5.7 1.1 1 0 0 1 1 1 0 Otopetrin CNDH2_M PF16869.5 CDJ53426.1 - 1.2 9.8 11.2 1.5 9.5 11.2 1.2 1 0 0 1 1 1 0 PF16858 AIF_C PF14721.6 CDJ53426.1 - 1.2 9.5 13.5 0.31 11.4 10.5 1.5 2 0 0 2 2 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FAM91_C PF14648.6 CDJ53426.1 - 1.3 7.8 7.9 1.3 7.7 7.9 1.1 1 0 0 1 1 1 0 FAM91 C-terminus CLN3 PF02487.17 CDJ53426.1 - 1.3 8.0 10.7 1.5 7.8 10.7 1.1 1 0 0 1 1 1 0 CLN3 protein Connexin PF00029.19 CDJ53426.1 - 1.3 8.7 12.2 1.8 8.3 12.2 1.2 1 0 0 1 1 1 0 Connexin EMC3_TMCO1 PF01956.16 CDJ53426.1 - 1.3 8.7 12.7 1.3 8.7 12.7 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like OATP PF03137.20 CDJ53426.1 - 1.5 7.0 7.1 1.4 7.1 7.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MRI PF15325.6 CDJ53426.1 - 1.6 9.8 7.3 1.2 10.3 4.3 2.0 1 1 1 2 2 2 0 Modulator of retrovirus infection Membralin PF09746.9 CDJ53426.1 - 1.7 7.6 9.0 1.7 7.6 9.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein Ndc1_Nup PF09531.10 CDJ53426.1 - 1.8 7.1 14.3 1.9 7.1 14.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC2_membrane_2 PF12679.7 CDJ53426.1 - 1.9 7.7 5.3 1.8 7.8 5.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein SLC12 PF03522.15 CDJ53426.1 - 2.4 7.1 18.6 2.9 6.8 18.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Pannexin_like PF12534.8 CDJ53426.1 - 2.5 7.1 10.9 3.4 6.7 10.9 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Peptidase_U57 PF05582.12 CDJ53426.1 - 2.7 7.2 12.6 3.4 6.8 12.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 PPL5 PF18168.1 CDJ53426.1 - 2.7 7.2 10.5 3.7 6.7 10.5 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Plasmodium_Vir PF05795.11 CDJ53426.1 - 3 7.2 8.5 3.3 7.0 8.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Zip PF02535.22 CDJ53426.1 - 3.1 6.9 5.7 2.8 7.1 5.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ureide_permease PF07168.11 CDJ53426.1 - 3.7 6.2 7.1 4.4 6.0 7.1 1.1 1 0 0 1 1 1 0 Ureide permease Tho2 PF11262.8 CDJ53426.1 - 4.4 6.4 15.7 5.1 6.2 15.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 GREB1 PF15782.5 CDJ53426.1 - 4.6 4.2 14.9 4.6 4.2 14.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MDM10 PF12519.8 CDJ53426.1 - 5.7 5.7 15.5 6.1 5.6 15.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Coilin_N PF15862.5 CDJ53426.1 - 6.1 6.6 18.4 13 5.5 18.4 1.6 1 0 0 1 1 1 0 Coilin N-terminus ALMT PF11744.8 CDJ53426.1 - 6.6 5.4 13.8 7.5 5.3 13.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PIP5K PF01504.18 CDJ53426.1 - 6.8 5.8 15.0 9.7 5.3 15.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase UPF0560 PF10577.9 CDJ53426.1 - 7 5.0 27.6 8.9 4.7 27.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Paramyxo_ncap PF00973.19 CDJ53426.1 - 7 5.4 10.2 6.4 5.6 10.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein YlqD PF11068.8 CDJ53426.1 - 8.3 6.8 36.7 15 5.9 36.7 1.4 1 0 0 1 1 1 0 YlqD protein CSG2 PF16965.5 CDJ53426.1 - 9 5.1 10.2 11 4.9 10.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator FPN1 PF06963.12 CDJ53426.1 - 9.6 4.6 9.0 11 4.5 9.0 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Baculo_PP31 PF05311.11 CDJ53426.1 - 10 5.5 20.1 15 4.9 20.1 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SID-1_RNA_chan PF13965.6 CDJ53426.1 - 10 4.4 8.9 11 4.2 8.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RAI16-like PF10257.9 CDJ53427.1 - 0.063 12.2 3.6 0.093 11.6 3.6 1.1 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein DUF1223 PF06764.11 CDJ53427.1 - 0.42 10.6 2.7 0.9 9.5 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) SR-25 PF10500.9 CDJ53427.1 - 6.1 6.4 24.4 1.3 8.6 5.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Exonuc_VII_L PF02601.15 CDJ53428.1 - 0.071 12.7 10.7 0.083 12.4 10.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RskA PF10099.9 CDJ53428.1 - 1.9 8.7 12.5 2.5 8.4 12.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA EphA2_TM PF14575.6 CDJ53429.1 - 0.00097 20.0 2.1 0.0035 18.2 0.9 2.6 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 CDJ53429.1 - 0.009 15.9 5.3 0.009 15.9 5.3 3.0 3 1 1 4 4 4 1 Transmembrane protein 51 FHIPEP PF00771.20 CDJ53429.1 - 0.011 14.3 3.5 0.016 13.7 3.5 1.2 1 0 0 1 1 1 0 FHIPEP family DUF4834 PF16118.5 CDJ53429.1 - 0.016 16.2 1.0 0.05 14.6 1.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2244 PF10003.9 CDJ53429.1 - 0.036 13.7 0.1 0.11 12.1 0.1 1.8 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF2722 PF10846.8 CDJ53429.1 - 0.038 12.9 8.4 0.079 11.9 8.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Baculo_11_kDa PF06143.11 CDJ53429.1 - 0.047 13.3 0.9 0.1 12.2 0.9 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family ABC2_membrane_2 PF12679.7 CDJ53429.1 - 0.056 12.7 4.4 0.091 12.0 4.4 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein SID-1_RNA_chan PF13965.6 CDJ53429.1 - 0.069 11.6 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 CDJ53429.1 - 0.13 10.2 1.0 0.25 9.2 1.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5531 PF17671.1 CDJ53429.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.3 3 0 0 3 3 2 0 Family of unknown function (DUF5531) DUF4199 PF13858.6 CDJ53429.1 - 0.48 10.8 1.3 0.77 10.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ExbD PF02472.16 CDJ53429.1 - 0.64 10.2 4.1 1.6 8.9 4.1 1.7 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF2681 PF10883.8 CDJ53429.1 - 1.1 9.8 15.4 0.43 11.0 12.2 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) DUF3742 PF12553.8 CDJ53429.1 - 1.2 9.2 4.2 0.59 10.3 1.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) OSTbeta PF15048.6 CDJ53429.1 - 2.4 8.3 4.9 1.1 9.5 0.4 2.4 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF3357 PF11837.8 CDJ53429.1 - 4.6 7.7 12.4 0.83 10.1 5.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Cadherin_C_2 PF16492.5 CDJ53429.1 - 5.7 7.8 6.4 0.82 10.5 0.1 2.8 3 1 0 3 3 3 0 Cadherin cytoplasmic C-terminal RskA PF10099.9 CDJ53429.1 - 6.8 6.9 40.0 0.14 12.4 19.3 2.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ53431.1 - 0.19 12.7 3.8 0.21 12.6 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SUIM_assoc PF16619.5 CDJ53431.1 - 0.25 11.4 13.3 0.93 9.6 13.3 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2681 PF10883.8 CDJ53431.1 - 3.7 8.0 13.1 0.041 14.3 5.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Spt20 PF12090.8 CDJ53431.1 - 8.6 5.9 17.0 0.43 10.2 11.0 1.7 2 0 0 2 2 2 0 Spt20 family Pkinase PF00069.25 CDJ53432.1 - 1.3e-07 31.3 0.0 1.3e-07 31.3 0.0 5.6 10 0 0 10 10 10 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ53432.1 - 0.0013 18.1 0.0 0.0013 18.1 0.0 4.2 5 0 0 5 5 5 1 Protein tyrosine kinase HA2 PF04408.23 CDJ53433.1 - 4.5e-26 91.2 0.0 1.2e-25 89.9 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ53433.1 - 5.1e-23 81.2 0.0 9.6e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ53433.1 - 3.6e-10 40.1 0.0 1.1e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ53433.1 - 5.6e-06 26.7 0.2 1.9e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 CDJ53433.1 - 1.5e-05 24.9 0.3 4.4e-05 23.3 0.3 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CDJ53433.1 - 0.002 17.9 0.0 0.0064 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDJ53433.1 - 0.0027 18.0 0.0 0.0069 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDJ53433.1 - 0.01 14.9 0.4 0.032 13.3 0.2 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.9 CDJ53433.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CDJ53433.1 - 0.051 13.0 0.3 0.14 11.6 0.3 1.7 1 0 0 1 1 1 0 PhoH-like protein Microtub_bd PF16796.5 CDJ53433.1 - 0.053 13.4 0.0 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Microtubule binding AAA_16 PF13191.6 CDJ53433.1 - 0.091 13.1 0.5 0.29 11.5 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain S1 PF00575.23 CDJ53434.1 - 7.2e-05 23.0 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain Methyltransf_34 PF11312.8 CDJ53434.1 - 0.17 11.1 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase PAPA-1 PF04795.12 CDJ53435.1 - 0.018 15.8 1.8 0.039 14.8 1.8 1.6 1 0 0 1 1 1 0 PAPA-1-like conserved region Lipoprotein_10 PF03202.13 CDJ53435.1 - 0.043 14.2 0.3 0.075 13.5 0.2 1.4 1 1 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region SUI1 PF01253.22 CDJ53436.1 - 4.6e-27 94.3 0.4 5.7e-27 94.1 0.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 CDJ53436.1 - 0.069 13.5 0.1 0.1 12.9 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) RNase_PH PF01138.21 CDJ53437.1 - 2.6e-13 50.6 0.0 4.2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 SpoIIP PF07454.11 CDJ53438.1 - 0.46 9.9 30.8 0.037 13.5 13.6 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) ASC PF00858.24 CDJ53438.1 - 0.96 8.3 7.5 0.57 9.1 2.2 2.1 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel TT_ORF1 PF02956.14 CDJ53438.1 - 1.6 7.3 18.5 0.12 11.0 6.7 2.1 2 0 0 2 2 2 0 TT viral orf 1 Spt20 PF12090.8 CDJ53440.1 - 0.0014 18.3 19.3 0.0015 18.2 19.3 1.1 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ53440.1 - 0.0017 17.4 15.1 0.0018 17.3 15.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ53440.1 - 0.11 12.4 23.3 0.13 12.2 23.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NST1 PF13945.6 CDJ53440.1 - 0.13 12.4 11.6 0.17 12.0 11.6 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Roughex PF06020.11 CDJ53440.1 - 0.17 11.0 10.8 0.16 11.0 10.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF4770 PF15994.5 CDJ53440.1 - 0.42 10.8 8.8 0.46 10.7 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF2126 PF09899.9 CDJ53440.1 - 0.89 7.6 5.7 0.85 7.6 5.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) UPF0524 PF15823.5 CDJ53440.1 - 1.4 8.3 5.9 2.2 7.6 5.9 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 RIFIN PF02009.16 CDJ53440.1 - 1.4 8.7 10.8 1.8 8.4 10.8 1.1 1 0 0 1 1 1 0 Rifin Band_3_cyto PF07565.13 CDJ53440.1 - 1.7 8.4 8.0 1.9 8.2 8.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ALMT PF11744.8 CDJ53440.1 - 2 7.1 7.6 2.3 6.9 7.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Sin_N PF04801.13 CDJ53440.1 - 3.3 6.8 14.9 3.4 6.8 14.9 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region BAF1_ABF1 PF04684.13 CDJ53440.1 - 3.5 6.6 12.6 4.2 6.3 12.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor eIF-3_zeta PF05091.12 CDJ53440.1 - 3.7 6.4 10.8 3.8 6.4 10.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ53440.1 - 4.8 6.1 8.5 5.2 6.0 8.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 HGTP_anticodon2 PF12745.7 CDJ53440.1 - 7.2 6.0 13.4 8.7 5.8 13.4 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Neur_chan_memb PF02932.16 CDJ53440.1 - 7.6 6.5 7.5 7.9 6.5 7.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ53440.1 - 7.9 5.1 12.5 9.2 4.9 12.5 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CDJ53440.1 - 9 6.9 20.4 15 6.2 20.4 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAP_assoc PF03828.19 CDJ53441.1 - 0.0096 16.1 0.1 0.022 14.9 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase SUIM_assoc PF16619.5 CDJ53441.1 - 0.18 11.9 36.8 0.17 11.9 2.7 5.1 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ53442.1 - 0.77 9.3 6.3 1.3 8.5 6.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4834 PF16118.5 CDJ53443.1 - 0.026 15.5 2.4 0.026 15.5 2.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Med15 PF09606.10 CDJ53443.1 - 0.064 11.9 54.1 0.096 11.4 54.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Exonuc_VII_L PF02601.15 CDJ53443.1 - 0.33 10.5 32.7 0.068 12.7 29.3 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Rit1_C PF17184.4 CDJ53443.1 - 0.81 9.1 10.8 1.4 8.4 10.8 1.3 1 0 0 1 1 1 0 Rit1 N-terminal domain Ribosomal_60s PF00428.19 CDJ53444.1 - 0.021 15.4 40.2 0.74 10.5 3.0 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein Pex14_N PF04695.13 CDJ53444.1 - 0.022 15.4 17.1 0.022 15.4 17.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Plasmodium_Vir PF05795.11 CDJ53444.1 - 0.03 13.8 4.9 0.037 13.5 4.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Clp1 PF06807.14 CDJ53444.1 - 0.03 14.7 0.1 0.03 14.7 0.1 2.3 2 1 0 2 2 1 0 Pre-mRNA cleavage complex II protein Clp1 OATP PF03137.20 CDJ53444.1 - 0.063 11.6 3.2 0.077 11.3 3.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4647 PF15504.6 CDJ53444.1 - 0.098 11.8 14.5 0.13 11.4 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF4638 PF15472.6 CDJ53444.1 - 0.31 10.8 9.8 0.031 14.0 5.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) EMC3_TMCO1 PF01956.16 CDJ53444.1 - 0.65 9.7 10.1 1.1 8.9 10.1 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FAM176 PF14851.6 CDJ53444.1 - 0.72 9.5 5.5 1.5 8.5 5.5 1.5 1 0 0 1 1 1 0 FAM176 family LCD1 PF09798.9 CDJ53444.1 - 0.73 8.3 7.0 0.92 8.0 7.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein F-protein PF00469.20 CDJ53444.1 - 0.77 9.3 7.8 1.4 8.4 7.8 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef PTPRCAP PF15713.5 CDJ53444.1 - 0.8 10.0 18.2 0.054 13.8 11.9 1.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Coilin_N PF15862.5 CDJ53444.1 - 0.83 9.5 16.2 1.9 8.3 16.2 1.5 1 0 0 1 1 1 0 Coilin N-terminus MAP65_ASE1 PF03999.12 CDJ53444.1 - 0.84 8.3 15.9 1.1 7.9 15.9 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Eapp_C PF10238.9 CDJ53444.1 - 1 9.4 13.0 0.12 12.5 8.1 1.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein Folate_carrier PF01770.18 CDJ53444.1 - 1.4 7.6 6.2 2.2 7.0 6.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier Rxt3 PF08642.10 CDJ53444.1 - 1.4 9.7 6.5 0.82 10.5 3.4 2.0 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 MCD PF05292.11 CDJ53444.1 - 1.5 8.3 11.9 0.24 10.9 6.9 1.9 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain Peptidase_S64 PF08192.11 CDJ53444.1 - 1.6 7.1 11.5 2 6.8 11.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 UPF0560 PF10577.9 CDJ53444.1 - 1.7 7.1 16.2 2.5 6.5 16.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Orf78 PF06024.12 CDJ53444.1 - 1.7 9.0 8.4 0.24 11.7 3.8 1.9 2 0 0 2 2 2 0 Orf78 (ac78) Draxin PF15550.6 CDJ53444.1 - 1.9 8.3 12.6 0.23 11.3 7.7 1.7 2 0 0 2 2 2 0 Draxin Spore_III_AF PF09581.10 CDJ53444.1 - 2 8.4 11.4 0.43 10.6 8.1 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Baculo_PP31 PF05311.11 CDJ53444.1 - 2.1 7.8 15.8 0.26 10.7 11.5 1.6 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Tim54 PF11711.8 CDJ53444.1 - 2.4 6.8 13.8 0.21 10.4 9.4 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CSG2 PF16965.5 CDJ53444.1 - 2.5 7.0 4.7 3.5 6.5 4.7 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Peptidase_S49_N PF08496.10 CDJ53444.1 - 2.6 8.1 17.8 2.8 8.0 13.4 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Miga PF10265.9 CDJ53444.1 - 2.9 6.8 11.2 3.4 6.5 11.2 1.2 1 0 0 1 1 1 0 Mitoguardin DUF3807 PF12720.7 CDJ53444.1 - 3 8.1 19.7 0.43 10.8 14.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF4834 PF16118.5 CDJ53444.1 - 4.5 8.3 13.8 2.7 9.0 11.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDJ53444.1 - 5.7 4.7 12.5 1.3 6.8 9.3 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family WASH-7_C PF14746.6 CDJ53444.1 - 5.9 6.5 14.9 1.3 8.7 10.8 1.8 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal MMR1 PF08505.10 CDJ53444.1 - 6.3 7.0 21.4 3.8 7.7 19.3 1.5 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein REC114-like PF15165.6 CDJ53444.1 - 6.4 6.5 16.2 0.42 10.3 10.7 1.8 2 0 0 2 2 2 0 Meiotic recombination protein REC114-like PAT1 PF09770.9 CDJ53444.1 - 8.1 4.6 26.9 11 4.2 26.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.7 CDJ53445.1 - 0.054 13.2 10.0 0.087 12.5 10.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Apt1 PF10351.9 CDJ53445.1 - 0.13 11.1 13.7 0.2 10.5 13.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain PPP4R2 PF09184.11 CDJ53445.1 - 1.1 8.9 7.9 1.3 8.5 7.9 1.2 1 0 0 1 1 1 0 PPP4R2 Secretin_N_2 PF07655.13 CDJ53445.1 - 1.3 9.6 22.4 0.1 13.1 9.6 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain GREB1 PF15782.5 CDJ53445.1 - 4.9 4.1 18.7 6.4 3.7 18.7 1.4 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 CDJ53445.1 - 5.7 5.5 24.3 7.9 5.0 24.3 1.1 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 CDJ53446.1 - 0.43 9.2 9.5 0.44 9.2 9.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ53446.1 - 0.73 8.5 4.9 0.76 8.5 4.9 1.2 1 0 0 1 1 1 0 Presenilin EIF4E-T PF10477.9 CDJ53446.1 - 0.81 8.4 14.2 0.85 8.4 13.3 1.4 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E NST1 PF13945.6 CDJ53446.1 - 2.2 8.3 9.8 4 7.5 9.8 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Nha1_C PF08619.10 CDJ53447.1 - 0.057 12.6 8.5 1.2 8.3 4.6 2.3 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF2464 PF10240.9 CDJ53447.1 - 4.5 6.8 5.9 6.8 6.2 0.3 2.1 2 0 0 2 2 2 0 Multivesicular body subunit 12 Brr6_like_C_C PF10104.9 CDJ53447.1 - 9.1 6.1 5.5 6 6.7 3.3 1.7 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain SR-25 PF10500.9 CDJ53447.1 - 9.4 5.8 42.0 0.31 10.6 9.4 2.6 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ53448.1 - 0.52 9.9 5.0 0.71 9.4 5.0 1.3 1 0 0 1 1 1 0 Spt20 family PAP1 PF08601.10 CDJ53448.1 - 2.9 7.5 8.4 3.5 7.3 8.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Roughex PF06020.11 CDJ53448.1 - 7.1 5.6 6.9 11 5.0 6.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein O-antigen_lig PF13425.6 CDJ53450.1 - 0.011 14.5 1.6 0.014 14.2 1.6 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PA26 PF04636.13 CDJ53450.1 - 0.019 13.9 3.4 0.023 13.6 3.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ASD2 PF08687.11 CDJ53450.1 - 0.04 13.5 15.4 0.051 13.1 15.4 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 SLC12 PF03522.15 CDJ53450.1 - 0.055 12.5 7.4 0.063 12.3 7.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 MctB PF11382.8 CDJ53450.1 - 0.067 12.9 0.6 0.067 12.9 0.6 2.0 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB Guanylate_cyc_2 PF09778.9 CDJ53450.1 - 0.07 12.5 1.0 0.17 11.3 0.1 2.0 1 1 0 2 2 2 0 Guanylylate cyclase FAM60A PF15396.6 CDJ53450.1 - 0.086 12.8 2.4 0.1 12.6 2.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CLN3 PF02487.17 CDJ53450.1 - 0.12 11.4 2.7 0.14 11.2 2.7 1.1 1 0 0 1 1 1 0 CLN3 protein Gti1_Pac2 PF09729.9 CDJ53450.1 - 0.13 12.3 4.9 0.17 12.0 4.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Plexin_cytopl PF08337.12 CDJ53450.1 - 0.16 10.6 4.6 0.19 10.4 4.6 1.1 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain OmpH PF03938.14 CDJ53450.1 - 0.16 12.3 30.8 0.26 11.6 30.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HemX PF04375.14 CDJ53450.1 - 0.2 10.9 23.3 0.27 10.5 23.3 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4064 PF13273.6 CDJ53450.1 - 0.28 11.5 0.7 1.5 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Suf PF05843.14 CDJ53450.1 - 0.57 10.1 12.5 0.77 9.7 12.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NPR3 PF03666.13 CDJ53450.1 - 0.79 8.4 8.4 0.9 8.3 8.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 EphA2_TM PF14575.6 CDJ53450.1 - 0.93 10.4 5.0 1.7 9.6 0.2 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CDC45 PF02724.14 CDJ53450.1 - 0.96 7.7 9.2 1.1 7.5 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Band_3_cyto PF07565.13 CDJ53450.1 - 0.98 9.2 8.7 1.3 8.7 8.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Sec62 PF03839.16 CDJ53450.1 - 1.3 8.5 9.6 1.7 8.1 9.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF913 PF06025.12 CDJ53450.1 - 1.3 7.9 5.6 1.5 7.7 5.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CDJ53450.1 - 1.3 8.8 15.7 1.6 8.5 15.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paramyxo_ncap PF00973.19 CDJ53450.1 - 1.4 7.8 10.4 1.7 7.5 10.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PIP5K PF01504.18 CDJ53450.1 - 2.9 7.0 7.7 3.9 6.6 7.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase PAT1 PF09770.9 CDJ53450.1 - 3.2 5.9 19.1 3.7 5.7 19.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rsc14 PF08586.10 CDJ53450.1 - 3.3 8.6 7.9 0.85 10.5 0.6 2.1 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Hid1 PF12722.7 CDJ53450.1 - 3.6 5.6 10.3 4 5.4 10.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 CDJ53450.1 - 4 7.4 7.6 5.5 7.0 7.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ53450.1 - 5.2 5.7 16.8 6.5 5.4 16.8 1.1 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 CDJ53450.1 - 5.6 4.9 11.2 7 4.6 11.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RNase_H2_suC PF08615.11 CDJ53450.1 - 5.6 7.1 14.6 1.8e+02 2.3 14.6 2.1 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) V_ATPase_I PF01496.19 CDJ53450.1 - 7.2 4.4 10.6 8.6 4.1 10.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 CDJ53450.1 - 7.6 6.4 24.4 0.11 12.3 5.4 2.2 2 0 0 2 2 2 0 Septum formation initiator Ndc1_Nup PF09531.10 CDJ53450.1 - 9.1 4.8 9.5 11 4.6 9.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM176 PF14851.6 CDJ53450.1 - 9.6 5.9 12.6 1.1e+02 2.5 12.9 1.9 1 1 1 2 2 2 0 FAM176 family Guanylate_cyc_2 PF09778.9 CDJ53451.1 - 4.5e-09 36.0 0.5 0.0022 17.4 0.0 2.5 2 0 0 2 2 2 2 Guanylylate cyclase Peptidase_C39 PF03412.15 CDJ53451.1 - 0.0032 17.3 0.1 0.0077 16.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase C39 family Nuc_deoxyri_tr2 PF15891.5 CDJ53451.1 - 0.41 11.0 3.1 2.1 8.7 0.2 2.4 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like Presenilin PF01080.17 CDJ53451.1 - 0.59 8.8 16.0 2 7.1 9.0 2.3 2 0 0 2 2 2 0 Presenilin Mem_trans PF03547.18 CDJ53452.1 - 0.054 11.9 0.1 0.077 11.4 0.1 1.3 1 0 0 1 1 1 0 Membrane transport protein Draxin PF15550.6 CDJ53452.1 - 0.16 11.9 8.6 0.41 10.5 1.7 2.3 2 0 0 2 2 2 0 Draxin CBP4 PF07960.11 CDJ53452.1 - 0.17 11.7 15.3 1.5 8.7 10.3 2.3 2 0 0 2 2 2 0 CBP4 G0-G1_switch_2 PF15103.6 CDJ53452.1 - 0.53 10.7 11.9 0.59 10.6 4.0 2.5 2 0 0 2 2 2 0 G0/G1 switch protein 2 Connexin PF00029.19 CDJ53452.1 - 0.59 9.8 4.8 0.43 10.3 2.2 1.8 2 0 0 2 2 2 0 Connexin OATP PF03137.20 CDJ53452.1 - 0.62 8.3 5.9 0.11 10.8 2.3 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Spore_III_AF PF09581.10 CDJ53452.1 - 0.69 9.9 8.9 1.1 9.2 4.1 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) DUF4355 PF14265.6 CDJ53452.1 - 0.69 10.2 17.9 1.1 9.4 7.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Folate_carrier PF01770.18 CDJ53452.1 - 0.78 8.4 3.5 1.4 7.6 3.5 1.3 1 0 0 1 1 1 0 Reduced folate carrier Baculo_PP31 PF05311.11 CDJ53452.1 - 0.93 8.9 9.2 2.2 7.7 6.5 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) FHIPEP PF00771.20 CDJ53452.1 - 0.94 7.9 8.3 0.069 11.6 1.8 1.9 2 0 0 2 2 2 0 FHIPEP family MecA PF05389.12 CDJ53452.1 - 1.1 8.8 7.5 0.86 9.2 3.3 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) NEMP PF10225.9 CDJ53452.1 - 2.8 7.6 5.7 6.2 6.4 5.7 1.5 1 0 0 1 1 1 0 NEMP family Spt20 PF12090.8 CDJ53452.1 - 2.9 7.4 36.4 0.26 10.9 29.6 2.2 3 0 0 3 3 2 0 Spt20 family Afi1 PF07792.12 CDJ53452.1 - 3.5 8.1 9.7 1.4 9.4 4.2 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MMU163 PF17119.5 CDJ53452.1 - 3.7 6.6 8.7 0.54 9.4 3.4 2.1 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis SpoIIP PF07454.11 CDJ53452.1 - 4.5 6.7 10.6 0.23 10.9 4.1 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 CDJ53452.1 - 6.2 6.9 17.3 5.2 7.1 8.9 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF1764 PF08576.10 CDJ53452.1 - 6.8 7.7 13.8 41 5.1 8.2 2.7 3 0 0 3 3 2 0 Eukaryotic protein of unknown function (DUF1764) DUF4834 PF16118.5 CDJ53452.1 - 7.6 7.6 17.5 0.13 13.3 7.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) EOS1 PF12326.8 CDJ53452.1 - 7.9 6.4 6.9 7.9 6.4 3.3 2.2 2 1 0 2 2 2 0 N-glycosylation protein DUF3408 PF11888.8 CDJ53452.1 - 7.9 6.6 12.9 3.3 7.8 6.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) tRNA_synt_1c_R2 PF04557.15 CDJ53452.1 - 9.5 7.2 12.7 3.9 8.4 2.4 2.8 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 FAM76 PF16046.5 CDJ53453.1 - 0.045 13.1 24.3 0.063 12.6 24.3 1.2 1 0 0 1 1 1 0 FAM76 protein ASC PF00858.24 CDJ53453.1 - 0.13 11.2 7.5 0.16 10.9 7.5 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel SR-25 PF10500.9 CDJ53453.1 - 1.8 8.1 33.9 0.46 10.1 7.9 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Grg1 PF11034.8 CDJ53454.1 - 0.27 11.5 27.0 27 5.1 0.7 3.6 1 1 1 2 2 2 0 Glucose-repressible protein Grg1 Trypan_PARP PF05887.11 CDJ53454.1 - 0.89 9.5 16.3 1 9.3 16.3 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 CDJ53454.1 - 7.3 6.1 23.2 45 3.5 23.2 1.9 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Red1 PF07964.11 CDJ53454.1 - 9.5 4.3 26.2 10 4.2 26.2 1.0 1 0 0 1 1 1 0 Rec10 / Red1 IMUP PF15761.5 CDJ53456.1 - 0.00097 19.8 1.1 0.0025 18.5 1.1 1.7 1 0 0 1 1 1 1 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ53456.1 - 0.0071 16.0 4.9 0.0071 16.0 4.9 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein ANAPC_CDC26 PF10471.9 CDJ53456.1 - 0.014 16.2 9.2 0.014 16.2 9.2 3.2 2 1 0 2 2 1 0 Anaphase-promoting complex APC subunit CDC26 Ycf54 PF10674.9 CDJ53456.1 - 0.13 12.5 3.1 0.96 9.8 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) EBP50_C PF09007.11 CDJ53456.1 - 0.32 12.0 14.3 0.4 11.7 2.7 2.1 2 0 0 2 2 2 0 EBP50, C-terminal Rieske_3 PF18465.1 CDJ53456.1 - 0.45 10.8 2.0 3.6 7.9 0.1 2.4 1 1 1 2 2 2 0 Rieske 3Fe-4S OmpH PF03938.14 CDJ53456.1 - 1.5 9.2 28.1 1.1 9.6 16.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) BRF1 PF07741.13 CDJ53456.1 - 2.7 8.4 14.1 0.55 10.6 0.4 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain FliP PF00813.20 CDJ53456.1 - 4.1 7.2 5.2 0.67 9.8 0.9 1.7 2 0 0 2 2 2 0 FliP family Activator_LAG-3 PF11498.8 CDJ53456.1 - 4.6 6.1 35.3 2 7.3 20.3 2.0 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF1980 PF09323.10 CDJ53456.1 - 8.9 6.2 7.8 3.5 7.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CSRNP_N PF16019.5 CDJ53456.1 - 9.1 6.1 13.9 1.3 8.9 1.4 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF3807 PF12720.7 CDJ53457.1 - 7.9 6.7 88.3 0.067 13.5 32.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) RskA PF10099.9 CDJ53458.1 - 0.0072 16.6 0.0 0.0072 16.6 0.0 21.4 3 2 11 15 15 15 1 Anti-sigma-K factor rskA Glyco_transf_20 PF00982.21 CDJ53460.1 - 2.6e-24 85.8 0.2 1.6e-16 60.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase family 20 BUD22 PF09073.10 CDJ53460.1 - 0.0044 16.4 8.5 0.0044 16.4 8.5 1.6 2 0 0 2 2 2 1 BUD22 PPP4R2 PF09184.11 CDJ53460.1 - 0.23 11.0 0.6 0.32 10.6 0.6 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 CDJ53460.1 - 1.4 7.0 10.3 1.8 6.7 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CDJ53460.1 - 6.5 6.1 11.2 9 5.6 11.2 1.2 1 0 0 1 1 1 0 SDA1 CENP-L PF13092.6 CDJ53462.1 - 0.42 10.8 3.7 0.93 9.7 3.7 1.8 1 1 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 PH PF00169.29 CDJ53463.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 PH domain YtxH PF12732.7 CDJ53465.1 - 0.031 14.8 1.1 0.031 14.8 1.1 4.0 3 2 1 4 4 4 0 YtxH-like protein RskA PF10099.9 CDJ53465.1 - 2.3 8.5 41.1 1.5 9.1 2.2 4.1 3 1 0 3 3 3 0 Anti-sigma-K factor rskA XRN_N PF03159.18 CDJ53466.1 - 2.1e-66 223.8 0.0 3.2e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CDJ53466.1 - 6.3e-51 173.7 8.3 2.1e-21 76.4 0.0 3.6 3 0 0 3 3 3 3 Xrn1 helical domain Glutaredoxin PF00462.24 CDJ53467.1 - 0.0049 17.1 0.0 0.0084 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Peptidase_S77 PF03420.13 CDJ53467.1 - 0.032 13.9 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Prohead core protein serine protease zf-C4pol PF14260.6 CDJ53471.1 - 0.17 12.4 0.8 0.71 10.4 0.4 2.2 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta EF-hand_7 PF13499.6 CDJ53472.1 - 2.7e-15 56.5 0.0 2e-06 28.1 0.1 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CDJ53472.1 - 4.3e-15 54.1 0.0 0.0055 16.2 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDJ53472.1 - 4.3e-13 48.0 0.0 0.0042 16.9 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CDJ53472.1 - 7e-09 35.4 0.3 0.16 11.8 0.0 4.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CDJ53472.1 - 1.1e-08 34.2 0.3 0.00084 18.7 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 CDJ53472.1 - 1e-06 29.0 0.0 0.00064 20.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CDJ53472.1 - 0.095 13.0 0.0 8.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region VIT1 PF01988.19 CDJ53473.1 - 1.1e-37 130.0 0.0 1.3e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 VIT family DUF1700 PF08006.11 CDJ53473.1 - 3.4 7.2 7.9 43 3.6 7.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) Spt20 PF12090.8 CDJ53474.1 - 0.4 10.3 10.5 0.47 10.0 10.5 1.1 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 CDJ53474.1 - 0.62 8.8 15.3 0.74 8.6 15.3 1.1 1 0 0 1 1 1 0 Androgen receptor Neur_chan_memb PF02932.16 CDJ53474.1 - 0.86 9.6 2.7 1.5 8.8 2.7 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOBP PF15279.6 CDJ53476.1 - 0.37 11.4 44.0 0.012 16.2 34.0 2.5 2 0 0 2 2 2 0 Sine oculis-binding protein DEAD PF00270.29 CDJ53478.1 - 3.6e-14 52.9 0.0 4e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABATE PF07336.11 CDJ53478.1 - 1.6 9.4 18.2 13 6.5 16.5 2.1 1 1 1 2 2 2 0 Putative stress-induced transcription regulator DUF5364 PF17322.2 CDJ53480.1 - 0.6 10.4 27.2 0.76 10.1 27.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5364) PPP4R2 PF09184.11 CDJ53480.1 - 7.7 6.0 13.0 12 5.4 13.0 1.2 1 0 0 1 1 1 0 PPP4R2 RTC4 PF14474.6 CDJ53481.1 - 0.14 12.4 6.1 0.46 10.7 1.4 2.2 1 1 1 2 2 2 0 RTC4-like domain CCSAP PF15748.5 CDJ53481.1 - 0.46 10.6 27.9 0.63 10.2 27.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SelP_N PF04592.14 CDJ53481.1 - 3.6 6.9 29.4 0.34 10.3 11.1 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region PIH1 PF08190.12 CDJ53483.1 - 1.1e-05 24.9 0.2 0.00033 20.2 0.0 4.6 6 0 0 6 6 6 2 PIH1 N-terminal domain SR-25 PF10500.9 CDJ53484.1 - 0.00049 19.8 12.5 0.00049 19.8 12.5 5.6 4 1 1 5 5 5 2 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ53484.1 - 0.0016 18.5 42.6 0.0016 18.5 42.6 4.1 4 2 1 5 5 5 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ53485.1 - 0.013 15.5 1.4 0.013 15.5 1.4 8.0 5 2 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Dehydrin PF00257.19 CDJ53485.1 - 0.087 13.4 0.4 0.087 13.4 0.4 8.0 5 2 1 6 6 6 0 Dehydrin Metallophos PF00149.28 CDJ53486.1 - 8e-23 82.0 0.0 1.2e-22 81.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TFIIA PF03153.13 CDJ53486.1 - 0.24 11.3 33.5 1.1 9.2 6.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ53487.1 - 0.0036 17.8 4.7 0.0036 17.8 4.7 2.8 2 1 0 2 2 2 1 60s Acidic ribosomal protein Rotamase_2 PF13145.6 CDJ53487.1 - 0.56 11.1 8.1 1.1 10.1 0.6 2.1 2 0 0 2 2 2 0 PPIC-type PPIASE domain Plasmodium_Vir PF05795.11 CDJ53489.1 - 3.2 7.1 15.3 1.3 8.4 10.0 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SR-25 PF10500.9 CDJ53490.1 - 0.00021 21.0 13.4 0.00021 21.0 13.4 2.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Utp14 PF04615.13 CDJ53490.1 - 0.0047 15.6 16.6 0.0051 15.5 16.6 1.1 1 0 0 1 1 1 1 Utp14 protein ATG22 PF11700.8 CDJ53490.1 - 0.19 10.4 11.8 0.052 12.2 1.7 2.6 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like Med15 PF09606.10 CDJ53490.1 - 0.25 10.0 60.9 0.28 9.8 60.9 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PMP22_Claudin PF00822.20 CDJ53490.1 - 0.58 10.0 0.0 0.58 10.0 0.0 2.3 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin family DUF1635 PF07795.11 CDJ53490.1 - 1.2 9.0 31.0 0.1 12.4 15.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Ctr PF04145.15 CDJ53490.1 - 2.7 8.6 18.5 3.1 8.4 2.6 2.3 2 0 0 2 2 2 0 Ctr copper transporter family TCP PF03634.13 CDJ53490.1 - 6.3 7.3 30.4 3.4 8.2 7.2 2.4 2 0 0 2 2 2 0 TCP family transcription factor DUF4207 PF13904.6 CDJ53490.1 - 8.5 6.0 41.9 5.6 6.6 8.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Herpes_capsid PF06112.11 CDJ53491.1 - 0.0013 18.9 7.8 0.0013 18.9 7.8 1.9 2 0 0 2 2 2 1 Gammaherpesvirus capsid protein PA26 PF04636.13 CDJ53491.1 - 1.6 7.6 10.3 2.1 7.2 10.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RAP1 PF07218.11 CDJ53492.1 - 1.3 7.2 21.9 0.0086 14.4 13.5 1.6 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Hamartin PF04388.12 CDJ53492.1 - 2 7.0 62.6 2.6 6.6 62.6 1.1 1 0 0 1 1 1 0 Hamartin protein zf-CCHC PF00098.23 CDJ53493.1 - 3.4e-10 39.5 10.9 7.2e-05 22.7 1.1 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 CDJ53493.1 - 0.0024 17.5 9.1 0.017 14.8 1.5 2.5 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger DnaJ_CXXCXGXG PF00684.19 CDJ53493.1 - 0.0042 17.4 5.1 0.0083 16.5 5.1 1.4 1 0 0 1 1 1 1 DnaJ central domain zf-CCHC_2 PF13696.6 CDJ53493.1 - 0.0045 16.8 0.8 0.0045 16.8 0.8 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDJ53493.1 - 0.022 14.7 4.6 0.67 10.0 0.6 2.4 1 1 1 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 CDJ53493.1 - 0.029 14.6 0.0 0.4 11.0 0.0 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein zf-CCHC_4 PF14392.6 CDJ53493.1 - 0.16 11.8 7.6 3.5 7.4 0.6 3.3 3 0 0 3 3 3 0 Zinc knuckle eIF3g PF12353.8 CDJ53493.1 - 2 8.8 6.5 13 6.2 1.2 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G SIS PF01380.22 CDJ53494.1 - 3.3e-34 117.5 0.4 5.6e-18 65.1 0.0 2.8 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 CDJ53494.1 - 8.3e-18 64.9 0.0 1.6e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CDJ53494.1 - 2.5e-12 46.8 0.0 4.6e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CDJ53494.1 - 8.6e-05 21.6 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II LRR_4 PF12799.7 CDJ53495.1 - 1.4e-09 38.0 17.8 0.0089 16.4 0.6 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ53495.1 - 0.00022 20.8 2.3 0.00089 18.8 0.7 2.1 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 CDJ53495.1 - 0.00032 20.4 16.3 0.0048 16.6 2.5 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 CDJ53495.1 - 0.073 13.7 20.0 6.6 7.7 0.6 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 CDJ53495.1 - 0.14 12.3 15.4 5.4 7.3 0.2 4.9 5 0 0 5 5 5 0 Leucine Rich repeat PCP_red PF08369.10 CDJ53495.1 - 0.16 12.2 0.5 0.55 10.5 0.2 2.0 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Phage_holin_6_1 PF09682.10 CDJ53496.1 - 0.03 14.8 0.5 0.062 13.7 0.5 1.5 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Coiled-coil_56 PF09813.9 CDJ53496.1 - 0.081 13.0 0.0 0.081 13.0 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Spt20 PF12090.8 CDJ53498.1 - 0.15 11.7 32.6 0.067 12.8 7.0 2.1 2 0 0 2 2 2 0 Spt20 family Fibin PF15819.5 CDJ53498.1 - 0.46 10.2 7.4 1.5 8.5 3.0 2.1 2 0 0 2 2 2 0 Fin bud initiation factor homologue DUF2489 PF10675.9 CDJ53498.1 - 2.3 8.1 18.2 1.9 8.4 7.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Mif2_N PF15624.6 CDJ53498.1 - 5.3 7.8 9.8 0.42 11.3 1.6 2.1 1 1 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal tRNA_lig_CPD PF08302.11 CDJ53498.1 - 8.5 5.7 11.7 1.4 8.3 3.1 2.1 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain E1-E2_ATPase PF00122.20 CDJ53499.1 - 5.2e-14 52.2 0.2 1.2e-12 47.8 0.0 3.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ53499.1 - 0.0015 18.9 0.6 0.0015 18.9 0.6 8.2 7 2 1 8 8 8 1 haloacid dehalogenase-like hydrolase RskA PF10099.9 CDJ53499.1 - 0.43 10.8 0.0 0.017 15.5 8.4 21.9 8 7 4 15 15 15 0 Anti-sigma-K factor rskA FATC PF02260.20 CDJ53500.1 - 2.2e-06 27.4 0.1 3.7e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 FATC domain SR-25 PF10500.9 CDJ53500.1 - 0.00095 18.8 25.9 0.018 14.6 9.6 3.0 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein RXLR PF16810.5 CDJ53500.1 - 0.0072 16.8 1.3 0.0072 16.8 1.3 2.9 3 1 0 3 3 2 1 RXLR phytopathogen effector protein, Avirulence activity SpoIIP PF07454.11 CDJ53500.1 - 0.13 11.7 15.3 0.036 13.5 4.2 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4179 PF13786.6 CDJ53500.1 - 0.14 12.6 2.0 1.1 9.7 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) Sec62 PF03839.16 CDJ53500.1 - 0.37 10.3 12.0 0.05 13.1 2.8 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 Pex14_N PF04695.13 CDJ53500.1 - 0.48 11.1 38.5 0.069 13.8 16.3 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region OATP PF03137.20 CDJ53500.1 - 1.8 6.8 7.0 0.54 8.5 1.5 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EPL1 PF10513.9 CDJ53500.1 - 2 8.8 22.4 0.072 13.5 4.9 2.9 3 0 0 3 3 3 0 Enhancer of polycomb-like Rxt3 PF08642.10 CDJ53500.1 - 2.4 9.0 10.1 1.6 9.5 1.2 2.8 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 DUF4746 PF15928.5 CDJ53500.1 - 3.7 6.9 11.3 0.14 11.6 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Folate_carrier PF01770.18 CDJ53500.1 - 4.5 5.9 9.0 0.91 8.2 1.7 2.1 2 0 0 2 2 2 0 Reduced folate carrier eIF-3_zeta PF05091.12 CDJ53500.1 - 5.3 5.9 27.5 1.9 7.4 3.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ureide_permease PF07168.11 CDJ53500.1 - 6.3 5.4 8.1 0.74 8.5 1.4 2.2 2 0 0 2 2 2 0 Ureide permease PEX11 PF05648.14 CDJ53500.1 - 9.6 5.6 14.0 0.07 12.6 0.4 2.7 3 0 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) RIFIN PF02009.16 CDJ53501.1 - 0.0012 18.9 0.9 0.0016 18.4 0.9 1.2 1 0 0 1 1 1 1 Rifin DDHD PF02862.17 CDJ53501.1 - 0.0012 19.0 4.4 0.0012 19.0 4.4 1.1 1 0 0 1 1 1 1 DDHD domain DUF4471 PF14740.6 CDJ53501.1 - 0.0022 17.3 1.1 0.0022 17.3 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) Presenilin PF01080.17 CDJ53501.1 - 0.0043 15.9 11.6 0.005 15.7 11.6 1.2 1 0 0 1 1 1 1 Presenilin Pex14_N PF04695.13 CDJ53501.1 - 0.0045 17.7 17.1 0.0069 17.0 17.1 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CobT PF06213.12 CDJ53501.1 - 0.0074 15.7 22.0 0.0088 15.5 22.0 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT FAM176 PF14851.6 CDJ53501.1 - 0.0087 15.7 7.0 0.014 15.1 7.0 1.3 1 0 0 1 1 1 1 FAM176 family SpoIIP PF07454.11 CDJ53501.1 - 0.023 14.2 12.1 0.024 14.1 12.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Draxin PF15550.6 CDJ53501.1 - 0.031 14.2 6.5 0.038 13.9 6.5 1.1 1 0 0 1 1 1 0 Draxin Dpy19 PF10034.9 CDJ53501.1 - 0.037 12.3 0.1 0.048 11.9 0.1 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation EMC3_TMCO1 PF01956.16 CDJ53501.1 - 0.052 13.3 4.3 0.06 13.1 4.3 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FRQ PF09421.10 CDJ53501.1 - 0.083 10.9 10.2 0.1 10.6 10.2 1.0 1 0 0 1 1 1 0 Frequency clock protein Eapp_C PF10238.9 CDJ53501.1 - 0.085 12.9 10.4 0.14 12.2 10.4 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein Ndc1_Nup PF09531.10 CDJ53501.1 - 0.085 11.5 6.3 0.092 11.4 6.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LptF_LptG PF03739.14 CDJ53501.1 - 0.086 11.7 0.2 0.11 11.4 0.2 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG TRAP_alpha PF03896.16 CDJ53501.1 - 0.11 11.7 4.2 0.14 11.3 4.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GREB1 PF15782.5 CDJ53501.1 - 0.12 9.5 10.1 0.14 9.3 10.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer UPF0565 PF10561.9 CDJ53501.1 - 0.12 11.5 3.1 0.14 11.3 3.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PTPRCAP PF15713.5 CDJ53501.1 - 0.13 12.5 18.2 0.18 12.1 18.2 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2052 PF09747.9 CDJ53501.1 - 0.18 11.9 16.2 0.22 11.6 16.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Otopetrin PF03189.13 CDJ53501.1 - 0.2 10.5 1.0 0.19 10.5 1.0 1.1 1 0 0 1 1 1 0 Otopetrin Sporozoite_P67 PF05642.11 CDJ53501.1 - 0.22 9.6 11.6 0.29 9.2 11.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tim54 PF11711.8 CDJ53501.1 - 0.23 10.2 10.5 0.26 10.0 10.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 CDJ53501.1 - 0.23 9.7 12.1 0.3 9.3 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SART-1 PF03343.13 CDJ53501.1 - 0.24 9.9 24.8 0.3 9.6 24.8 1.0 1 0 0 1 1 1 0 SART-1 family DUF3402 PF11882.8 CDJ53501.1 - 0.47 9.5 14.3 0.58 9.2 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) SLC12 PF03522.15 CDJ53501.1 - 0.63 9.0 13.2 0.74 8.8 13.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4554 PF15091.6 CDJ53501.1 - 0.77 8.6 10.3 0.9 8.4 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) TFIIA PF03153.13 CDJ53501.1 - 0.92 9.4 40.7 1.1 9.2 40.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.13 CDJ53501.1 - 1 8.1 12.4 1.2 7.8 12.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ALMT PF11744.8 CDJ53501.1 - 1.1 8.0 10.9 1.3 7.7 10.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 CDJ53501.1 - 1.2 9.2 13.0 1.5 8.8 13.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF913 PF06025.12 CDJ53501.1 - 1.3 7.9 8.3 1.5 7.8 8.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BAF1_ABF1 PF04684.13 CDJ53501.1 - 2 7.4 18.0 2.6 7.0 18.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4746 PF15928.5 CDJ53501.1 - 2 7.8 11.9 2.5 7.4 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MMR1 PF08505.10 CDJ53501.1 - 2.4 8.4 16.5 3.3 7.9 16.5 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RR_TM4-6 PF06459.12 CDJ53501.1 - 2.5 7.9 16.6 3.2 7.5 16.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CLN3 PF02487.17 CDJ53501.1 - 2.5 7.1 11.0 3.6 6.5 11.0 1.3 1 0 0 1 1 1 0 CLN3 protein DUF2828 PF11443.8 CDJ53501.1 - 3.7 5.5 16.2 4.4 5.3 16.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CPSF100_C PF13299.6 CDJ53501.1 - 3.8 7.7 13.8 5.3 7.2 13.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Paf1 PF03985.13 CDJ53501.1 - 4 6.3 21.5 5 6.0 21.5 1.0 1 0 0 1 1 1 0 Paf1 Gti1_Pac2 PF09729.9 CDJ53501.1 - 4.1 7.5 12.1 5.3 7.1 12.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family MDM10 PF12519.8 CDJ53501.1 - 4.4 6.1 10.8 5.4 5.8 10.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FAM222A PF15258.6 CDJ53501.1 - 4.6 6.2 28.2 6.4 5.8 28.2 1.2 1 0 0 1 1 1 0 Protein family of FAM222A DUF5427 PF10310.9 CDJ53501.1 - 5.1 5.9 21.0 6.7 5.5 21.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PPL5 PF18168.1 CDJ53501.1 - 5.4 6.2 10.6 6.8 5.9 10.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 PAT1 PF09770.9 CDJ53501.1 - 6.1 5.0 25.9 7 4.8 25.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Afi1 PF07792.12 CDJ53501.1 - 6.2 7.3 14.7 8.7 6.8 14.7 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Baculo_PP31 PF05311.11 CDJ53501.1 - 6.7 6.1 13.8 8.2 5.8 13.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) YABBY PF04690.13 CDJ53501.1 - 6.9 7.2 12.5 9.9 6.7 12.5 1.2 1 0 0 1 1 1 0 YABBY protein V_ATPase_I PF01496.19 CDJ53501.1 - 7.7 4.3 20.3 9.3 4.0 18.7 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Endonuc_Holl PF10107.9 CDJ53501.1 - 8.6 6.2 12.6 11 5.8 12.6 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Peptidase_S64 PF08192.11 CDJ53501.1 - 9 4.6 12.0 11 4.4 12.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 XRN_M PF17846.1 CDJ53501.1 - 9.1 5.1 10.6 11 4.9 10.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Band_3_cyto PF07565.13 CDJ53501.1 - 9.6 5.9 15.0 11 5.7 15.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain LRRC37AB_C PF14914.6 CDJ53501.1 - 9.9 6.1 16.1 18 5.2 16.1 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain TFIIA PF03153.13 CDJ53502.1 - 0.096 12.7 28.0 0.13 12.2 28.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ53502.1 - 0.14 12.2 10.8 0.21 11.6 10.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PI3K_1B_p101 PF10486.9 CDJ53502.1 - 0.48 8.2 14.6 0.61 7.8 14.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RR_TM4-6 PF06459.12 CDJ53502.1 - 7.6 6.3 19.0 10 5.8 19.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RLL PF10036.9 CDJ53502.1 - 7.9 6.2 17.9 13 5.6 17.9 1.3 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Mito_carr PF00153.27 CDJ53503.1 - 0.00015 21.6 0.1 0.00015 21.6 0.1 3.4 5 0 0 5 5 5 1 Mitochondrial carrier protein SR-25 PF10500.9 CDJ53503.1 - 0.0047 16.6 3.3 0.0047 16.6 3.3 2.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ53503.1 - 0.013 15.1 1.9 0.013 15.1 1.9 3.0 2 1 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ53503.1 - 0.025 13.5 0.1 0.025 13.5 0.1 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF2722) IMUP PF15761.5 CDJ53503.1 - 0.11 13.1 7.2 0.38 11.5 7.2 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein CCSAP PF15748.5 CDJ53503.1 - 1.6 8.8 16.1 0.19 11.9 9.2 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF3446 PF11928.8 CDJ53503.1 - 2.7 8.3 17.0 0.046 14.0 4.4 3.2 3 0 0 3 3 3 0 Early growth response N-terminal domain Dehydrin PF00257.19 CDJ53504.1 - 0.098 13.2 12.6 0.1 13.2 6.4 2.4 2 0 0 2 2 2 0 Dehydrin SR-25 PF10500.9 CDJ53504.1 - 1.9 8.1 19.6 7.4 6.1 19.6 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PIP5K PF01504.18 CDJ53504.1 - 6.6 5.9 14.8 1.4 8.1 1.9 2.0 1 1 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase RskA PF10099.9 CDJ53505.1 - 0.00044 20.6 5.4 0.00044 20.6 5.4 5.6 2 2 2 4 4 4 2 Anti-sigma-K factor rskA PHC2_SAM_assoc PF16616.5 CDJ53505.1 - 0.0046 17.8 4.9 0.0046 17.8 4.9 6.3 4 2 2 6 6 6 1 Unstructured region on Polyhomeotic-like protein 1 and 2 AAA_23 PF13476.6 CDJ53505.1 - 0.0074 16.8 4.6 0.0074 16.8 4.6 3.3 3 0 0 3 3 3 2 AAA domain DUF4834 PF16118.5 CDJ53505.1 - 0.017 16.0 4.6 0.017 16.0 4.6 5.7 4 1 0 4 4 4 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CDJ53505.1 - 5.4 6.7 36.4 0.64 9.7 0.5 4.0 4 0 0 4 4 4 0 Connexin CitMHS_2 PF16980.5 CDJ53506.1 - 0.73 8.4 4.1 1.9 7.0 4.1 1.7 1 0 0 1 1 1 0 Putative citrate transport RskA PF10099.9 CDJ53508.1 - 0.0094 16.3 1.4 0.0094 16.3 1.4 9.1 5 4 2 7 7 7 2 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ53508.1 - 0.013 15.6 4.2 0.013 15.6 4.2 5.7 6 0 0 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 DUF5063 PF16702.5 CDJ53508.1 - 0.014 15.7 1.5 0.025 15.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) Spt20 PF12090.8 CDJ53508.1 - 0.017 14.7 26.8 0.02 14.5 13.9 3.2 3 0 0 3 3 3 0 Spt20 family DUF3446 PF11928.8 CDJ53509.1 - 0.91 9.9 39.5 0.064 13.6 13.2 3.9 4 0 0 4 4 4 0 Early growth response N-terminal domain YTH PF04146.15 CDJ53510.1 - 2.9e-06 27.4 28.2 2.9e-06 27.4 28.2 4.0 2 2 0 2 2 2 1 YT521-B-like domain Presenilin PF01080.17 CDJ53510.1 - 1 8.1 41.4 0.054 12.2 5.1 2.6 3 0 0 3 3 3 0 Presenilin O-antigen_lig PF13425.6 CDJ53510.1 - 3.2 6.5 4.7 8 5.1 4.7 1.7 1 0 0 1 1 1 0 O-antigen ligase like membrane protein UPF0564 PF10595.9 CDJ53510.1 - 5.3 6.0 41.6 0.27 10.2 35.3 2.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0564 ATP12 PF07542.11 CDJ53511.1 - 0.0018 18.3 11.0 0.0018 18.3 11.0 3.3 2 1 0 2 2 2 1 ATP12 chaperone protein Macoilin PF09726.9 CDJ53511.1 - 0.0021 16.7 27.3 0.0027 16.4 27.0 1.3 1 1 0 1 1 1 1 Macoilin family DUF2722 PF10846.8 CDJ53511.1 - 0.0067 15.4 10.6 0.0067 15.4 10.6 3.1 3 1 1 4 4 2 1 Protein of unknown function (DUF2722) CAF1 PF04857.20 CDJ53511.1 - 0.017 14.3 0.6 0.018 14.2 0.6 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease Lin-8 PF03353.15 CDJ53511.1 - 0.28 10.7 16.3 0.1 12.2 7.9 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ53511.1 - 0.5 10.2 18.6 0.48 10.3 5.2 2.1 2 0 0 2 2 2 0 SPX domain CLN3 PF02487.17 CDJ53511.1 - 1.2 8.1 5.8 2.5 7.1 5.8 1.5 1 0 0 1 1 1 0 CLN3 protein MAT1 PF06391.13 CDJ53511.1 - 4.9 6.9 22.1 0.14 11.9 7.3 2.7 3 0 0 3 3 3 0 CDK-activating kinase assembly factor MAT1 V_ATPase_I PF01496.19 CDJ53511.1 - 6.9 4.5 11.2 11 3.8 11.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spore_YhcN_YlaJ PF09580.10 CDJ53511.1 - 9.1 6.3 13.9 20 5.2 13.8 1.5 1 1 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) TFIIA PF03153.13 CDJ53511.1 - 9.7 6.1 55.8 12 5.8 54.5 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.11 CDJ53512.1 - 0.0039 17.4 10.8 0.0039 17.4 10.8 5.0 5 0 0 5 5 5 1 Domain of unknown function (DUF755) RskA PF10099.9 CDJ53512.1 - 0.0063 16.8 8.9 0.0063 16.8 8.9 5.1 3 1 2 5 5 5 1 Anti-sigma-K factor rskA FAM176 PF14851.6 CDJ53512.1 - 0.11 12.2 0.8 0.44 10.2 0.0 2.3 2 0 0 2 2 2 0 FAM176 family EphA2_TM PF14575.6 CDJ53512.1 - 8.8 7.3 7.8 13 6.7 0.6 3.9 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Pex14_N PF04695.13 CDJ53513.1 - 0.97 10.1 21.3 1.3 9.7 21.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SLC12 PF03522.15 CDJ53513.1 - 2.1 7.3 10.5 2.1 7.3 10.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ53513.1 - 2.8 6.6 16.1 3 6.5 16.1 1.0 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 CDJ53513.1 - 2.9 7.6 9.6 4 7.2 9.6 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4407 PF14362.6 CDJ53513.1 - 2.9 7.1 15.8 3.3 7.0 15.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 CDJ53513.1 - 3.7 7.3 11.3 4.1 7.2 11.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 CDJ53513.1 - 4.4 7.2 35.8 4.6 7.1 35.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ53513.1 - 5 6.6 17.8 5.5 6.5 17.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist YABBY PF04690.13 CDJ53513.1 - 5.5 7.5 12.5 7 7.2 12.5 1.1 1 0 0 1 1 1 0 YABBY protein Neur_chan_memb PF02932.16 CDJ53513.1 - 9 6.3 14.3 9.2 6.2 14.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.32 CDJ53514.1 - 6e-12 45.9 10.3 0.0043 17.9 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ53514.1 - 0.0091 16.3 0.0 5.5 7.4 0.0 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 CDJ53514.1 - 0.018 15.2 0.2 0.018 15.2 0.2 2.3 3 0 0 3 3 3 0 WD40 associated region in TFIID subunit, NTD2 domain Ribosomal_L30_N PF08079.12 CDJ53515.1 - 2.3e-15 56.6 14.1 4.9e-15 55.5 14.1 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CDJ53515.1 - 2e-14 53.2 0.7 3.7e-14 52.3 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S8e PF01201.22 CDJ53515.1 - 0.11 12.7 0.5 0.15 12.2 0.5 1.3 1 0 0 1 1 1 0 Ribosomal protein S8e PGC7_Stella PF15549.6 CDJ53515.1 - 0.64 10.0 2.3 1.3 9.0 2.3 1.4 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Ribosomal_L11 PF00298.19 CDJ53516.1 - 1e-17 64.4 0.1 1.6e-17 63.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 CDJ53516.1 - 2e-07 30.7 0.1 3.2e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain gerPA PF10676.9 CDJ53516.1 - 0.057 13.7 0.0 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 Spore germination protein gerPA/gerPF Steroid_dh PF02544.16 CDJ53517.1 - 2.2e-09 37.5 0.0 1.3e-06 28.4 0.0 3.3 3 0 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF4834 PF16118.5 CDJ53517.1 - 0.00056 20.8 0.5 12 6.9 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4834) Shisa PF13908.6 CDJ53517.1 - 0.0014 18.9 3.7 0.0047 17.2 0.3 2.2 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator TctB PF07331.11 CDJ53517.1 - 0.003 17.8 0.7 0.018 15.3 0.7 2.3 1 1 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family Ctr PF04145.15 CDJ53517.1 - 0.027 15.1 2.3 1.2 9.7 0.9 2.2 2 0 0 2 2 2 0 Ctr copper transporter family FAM104 PF15434.6 CDJ53517.1 - 0.043 14.4 5.6 0.043 14.4 5.6 2.2 2 0 0 2 2 2 0 Family 104 DUF1295 PF06966.12 CDJ53517.1 - 0.089 12.3 0.1 24 4.3 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1295) RskA PF10099.9 CDJ53517.1 - 1.1 9.6 15.4 0.39 11.0 4.1 3.0 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF4153 PF13687.6 CDJ53517.1 - 1.3 8.6 7.0 0.45 10.1 3.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4153) WWE PF02825.20 CDJ53519.1 - 2.1e-09 37.9 3.5 0.00028 21.4 0.1 3.4 3 0 0 3 3 3 2 WWE domain zf-RING_2 PF13639.6 CDJ53519.1 - 0.00013 22.2 14.0 0.0014 18.9 10.2 2.4 2 0 0 2 2 2 1 Ring finger domain SPX PF03105.19 CDJ53519.1 - 0.00048 20.2 6.1 0.00048 20.2 6.1 2.5 2 1 0 2 2 1 1 SPX domain zf-RING_11 PF17123.5 CDJ53519.1 - 0.0012 18.6 8.3 0.22 11.3 3.8 2.5 2 0 0 2 2 2 2 RING-like zinc finger zf-rbx1 PF12678.7 CDJ53519.1 - 0.017 15.4 7.8 0.017 15.4 7.8 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain DTC PF18102.1 CDJ53519.1 - 0.021 15.0 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Deltex C-terminal domain zf-C3HC4 PF00097.25 CDJ53519.1 - 0.11 12.4 15.0 0.12 12.3 9.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ53519.1 - 0.78 9.8 5.2 1.4 9.0 3.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Hamartin PF04388.12 CDJ53519.1 - 1.8 7.2 11.4 0.72 8.4 5.1 2.1 2 0 0 2 2 2 0 Hamartin protein zf-RING_UBOX PF13445.6 CDJ53519.1 - 2.8 8.1 9.9 12 6.0 6.1 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Presenilin PF01080.17 CDJ53519.1 - 5.3 5.7 18.8 0.85 8.3 1.1 2.2 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 CDJ53519.1 - 6.2 6.8 7.4 22 5.0 0.4 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-C3HC4_2 PF13923.6 CDJ53519.1 - 6.6 6.7 14.9 7.5 6.5 11.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S19e PF01090.19 CDJ53520.1 - 5.9e-51 171.8 0.0 7.4e-51 171.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 CDJ53520.1 - 0.00071 19.5 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain MarR_2 PF12802.7 CDJ53520.1 - 0.068 13.1 0.0 0.4 10.6 0.0 2.2 3 0 0 3 3 3 0 MarR family AP_endonuc_2 PF01261.24 CDJ53521.1 - 4.4e-32 111.2 0.0 6.5e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel RR_TM4-6 PF06459.12 CDJ53521.1 - 0.64 9.8 9.1 1.2 8.9 9.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Chorein_N PF12624.7 CDJ53522.1 - 1.3e-29 102.6 0.1 1.3e-29 102.6 0.1 5.8 5 0 0 5 5 5 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CDJ53522.1 - 1.4e-14 54.5 0.0 3.2e-13 50.0 0.0 2.9 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 CDJ53522.1 - 1.6e-07 31.0 0.3 1.7e-06 27.6 0.0 2.8 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 CDJ53522.1 - 4.3e-05 23.8 0.0 0.00082 19.7 0.0 3.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 CDJ53522.1 - 0.18 11.6 1.8 25 4.6 0.1 3.4 3 0 0 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal Carboxyl_trans PF01039.22 CDJ53523.1 - 3.8e-152 507.4 0.9 3.6e-150 500.9 0.9 2.2 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CDJ53523.1 - 1.3e-49 168.5 0.0 2.9e-49 167.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CDJ53523.1 - 3.5e-25 88.7 0.0 1.9e-24 86.3 0.0 2.3 1 1 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CDJ53523.1 - 1.5e-21 76.5 0.0 3.2e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ACC_central PF08326.12 CDJ53523.1 - 1e-18 67.0 0.5 1.3e-12 46.8 0.2 3.3 3 0 0 3 3 3 3 Acetyl-CoA carboxylase, central region Biotin_lipoyl PF00364.22 CDJ53523.1 - 1.2e-10 41.1 0.0 3e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 CDJ53523.1 - 9.2e-08 31.8 0.0 9.2e-08 31.8 0.0 2.5 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CDJ53523.1 - 3.9e-05 23.3 0.0 8.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 CDJ53523.1 - 0.001 18.8 0.0 0.001 18.8 0.0 3.2 3 0 0 3 3 3 1 Biotin-lipoyl like TFIIA PF03153.13 CDJ53523.1 - 0.0035 17.4 9.0 0.0035 17.4 9.0 5.9 3 1 0 4 4 4 1 Transcription factor IIA, alpha/beta subunit Dsh_C PF12316.8 CDJ53524.1 - 1.6 9.1 10.4 1.4 9.3 9.8 1.2 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal IMUP PF15761.5 CDJ53525.1 - 0.013 16.2 10.7 0.013 16.2 10.7 4.1 2 1 1 3 3 3 0 Immortalisation up-regulated protein Plasmodium_Vir PF05795.11 CDJ53525.1 - 1.3 8.4 8.3 1.6 8.1 8.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF572 PF04502.13 CDJ53525.1 - 6.4 6.3 10.6 8.1 6.0 10.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SNF2_N PF00176.23 CDJ53527.1 - 0.0016 17.3 0.9 0.0026 16.5 0.9 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SR-25 PF10500.9 CDJ53527.1 - 0.002 17.8 5.7 0.0039 16.8 5.7 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.8 CDJ53527.1 - 1.6 7.7 20.9 0.35 9.8 8.8 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 RskA PF10099.9 CDJ53528.1 - 0.19 12.0 7.4 0.21 11.9 7.4 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4820 PF16091.5 CDJ53528.1 - 0.24 10.8 8.4 0.23 10.8 8.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SpoIIP PF07454.11 CDJ53528.1 - 0.26 10.7 11.5 0.24 10.8 11.5 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) R_equi_Vir PF05526.11 CDJ53528.1 - 0.3 10.9 4.8 0.34 10.8 4.8 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein CPSF100_C PF13299.6 CDJ53528.1 - 0.37 11.0 8.6 0.37 11.0 8.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 CDJ53528.1 - 0.46 9.4 6.0 0.42 9.5 6.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 CDJ53528.1 - 0.49 10.5 9.0 0.45 10.7 9.0 1.0 1 0 0 1 1 1 0 DDHD domain DUF4834 PF16118.5 CDJ53528.1 - 0.57 11.2 14.9 0.61 11.1 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ53528.1 - 0.6 9.8 12.0 0.75 9.4 12.0 1.1 1 0 0 1 1 1 0 FAM176 family Pex14_N PF04695.13 CDJ53528.1 - 0.67 10.6 13.9 0.66 10.6 13.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1980 PF09323.10 CDJ53528.1 - 1 9.3 7.3 0.99 9.3 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 CDJ53528.1 - 1 8.0 12.3 1 8.1 12.3 1.0 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ53528.1 - 1.3 7.9 13.8 1.2 8.0 13.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ53528.1 - 1.7 8.5 26.0 1.7 8.6 26.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glt_symporter PF03616.14 CDJ53528.1 - 1.8 7.2 2.8 1.9 7.1 2.8 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter FHIPEP PF00771.20 CDJ53528.1 - 2 6.8 7.9 1.9 6.9 7.9 1.0 1 0 0 1 1 1 0 FHIPEP family EOS1 PF12326.8 CDJ53528.1 - 2 8.3 4.0 2 8.4 4.0 1.1 1 0 0 1 1 1 0 N-glycosylation protein Ctr PF04145.15 CDJ53528.1 - 2.1 9.0 3.6 2 9.1 3.6 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DcuA_DcuB PF03605.14 CDJ53528.1 - 3.3 6.5 3.8 3.3 6.5 3.8 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Coilin_N PF15862.5 CDJ53528.1 - 3.7 7.4 14.8 4.1 7.2 14.8 1.1 1 0 0 1 1 1 0 Coilin N-terminus Band_3_cyto PF07565.13 CDJ53528.1 - 4 7.2 10.7 4.3 7.1 10.7 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AIF_C PF14721.6 CDJ53528.1 - 4.3 7.7 10.2 4.5 7.6 10.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SID-1_RNA_chan PF13965.6 CDJ53528.1 - 4.4 5.6 4.9 4 5.7 4.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ53528.1 - 4.9 7.1 7.1 4.5 7.3 7.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ureide_permease PF07168.11 CDJ53528.1 - 5.8 5.6 6.4 5.8 5.6 6.4 1.0 1 0 0 1 1 1 0 Ureide permease Serinc PF03348.15 CDJ53528.1 - 8 5.3 8.2 7.4 5.4 8.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4407 PF14362.6 CDJ53528.1 - 8.1 5.7 13.6 7.6 5.8 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tim54 PF11711.8 CDJ53528.1 - 8.4 5.1 13.7 8.9 5.0 13.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spt20 PF12090.8 CDJ53528.1 - 8.4 5.9 34.2 9.5 5.8 34.2 1.1 1 0 0 1 1 1 0 Spt20 family EIIBC-GUT_N PF03612.14 CDJ53528.1 - 9.2 6.0 13.9 10 5.8 13.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CSG2 PF16965.5 CDJ53528.1 - 9.2 5.1 5.9 8.9 5.1 5.9 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator AAA_23 PF13476.6 CDJ53528.1 - 9.9 6.6 18.1 10 6.6 18.1 1.0 1 0 0 1 1 1 0 AAA domain HSD3 PF15244.6 CDJ53529.1 - 0.25 10.8 14.3 0.02 14.4 7.9 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 7, or HSD3 AbLIM_anchor PF16182.5 CDJ53529.1 - 8.8 6.0 16.4 0.86 9.4 9.8 2.1 2 0 0 2 2 2 0 Putative adherens-junction anchoring region of AbLIM Spt20 PF12090.8 CDJ53530.1 - 0.00072 19.2 12.0 0.0011 18.6 12.0 1.3 1 0 0 1 1 1 1 Spt20 family DUF4504 PF14953.6 CDJ53530.1 - 0.1 12.0 1.7 0.15 11.4 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) Presenilin PF01080.17 CDJ53530.1 - 0.18 10.6 6.8 0.24 10.1 6.8 1.2 1 0 0 1 1 1 0 Presenilin Myc_N PF01056.18 CDJ53530.1 - 0.23 11.3 14.4 0.23 11.3 5.6 2.1 2 0 0 2 2 2 0 Myc amino-terminal region RLL PF10036.9 CDJ53530.1 - 0.35 10.7 8.9 0.49 10.2 8.9 1.4 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Peroxin-3 PF04882.12 CDJ53530.1 - 0.74 8.7 5.8 1 8.3 5.8 1.2 1 0 0 1 1 1 0 Peroxin-3 DUF966 PF06136.13 CDJ53530.1 - 0.99 9.1 7.4 1.2 8.8 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4604 PF15377.6 CDJ53530.1 - 3.3 8.1 17.2 7.7 6.9 17.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) IER PF05760.12 CDJ53530.1 - 6.1 7.1 28.8 0.54 10.5 23.9 1.7 2 0 0 2 2 2 0 Immediate early response protein (IER) RskA PF10099.9 CDJ53531.1 - 0.00011 22.6 57.5 0.011 16.1 16.3 3.1 2 1 1 3 3 3 2 Anti-sigma-K factor rskA Activator_LAG-3 PF11498.8 CDJ53531.1 - 0.00013 21.1 26.7 0.00013 21.1 26.7 2.6 3 0 0 3 3 2 2 Transcriptional activator LAG-3 DUF4148 PF13663.6 CDJ53531.1 - 0.092 12.9 0.5 0.092 12.9 0.5 3.9 2 1 0 2 2 1 0 Domain of unknown function (DUF4148) Rxt3 PF08642.10 CDJ53531.1 - 0.15 12.9 10.2 2.2 9.0 0.2 2.5 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 CNDH2_C PF16858.5 CDJ53531.1 - 0.18 11.6 15.8 2.6 7.9 10.2 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RPOL_N PF14700.6 CDJ53531.1 - 0.28 10.5 20.5 1.6 8.1 1.3 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal Spt20 PF12090.8 CDJ53531.1 - 0.53 9.9 60.2 0.86 9.2 14.4 2.3 2 0 0 2 2 2 0 Spt20 family PIEZO PF15917.5 CDJ53531.1 - 0.56 9.6 22.0 1.4 8.3 13.1 2.1 2 0 0 2 2 2 0 Piezo MecA PF05389.12 CDJ53531.1 - 0.56 9.8 17.4 0.36 10.4 7.1 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) MMR1 PF08505.10 CDJ53531.1 - 0.98 9.7 37.7 0.52 10.6 15.4 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF2052 PF09747.9 CDJ53531.1 - 1.1 9.4 23.6 0.7 10.0 4.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF572 PF04502.13 CDJ53531.1 - 1.1 8.8 28.9 0.021 14.5 5.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) PA26 PF04636.13 CDJ53531.1 - 1.2 7.9 19.1 0.62 8.9 1.6 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) eIF-3_zeta PF05091.12 CDJ53531.1 - 1.4 7.8 29.3 2.3 7.1 5.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RAB3GAP2_N PF14655.6 CDJ53531.1 - 1.5 8.0 18.8 0.25 10.6 7.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4569 PF15133.6 CDJ53531.1 - 1.5 8.5 24.8 0.49 10.1 9.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) Caldesmon PF02029.15 CDJ53531.1 - 1.6 7.4 26.5 0.13 10.9 4.6 2.1 2 0 0 2 2 2 0 Caldesmon DUF2232 PF09991.9 CDJ53531.1 - 1.6 7.9 13.5 0.11 11.6 5.7 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) TFB6 PF17110.5 CDJ53531.1 - 1.6 8.4 16.5 2.6 7.7 3.0 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH EIF4E-T PF10477.9 CDJ53531.1 - 1.7 7.4 30.2 1.3 7.7 5.5 2.2 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Filament_head PF04732.14 CDJ53531.1 - 1.7 9.6 24.8 1.1 10.1 15.4 2.9 3 0 0 3 3 2 0 Intermediate filament head (DNA binding) region MAT1 PF06391.13 CDJ53531.1 - 2 8.2 28.6 2 8.2 15.4 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 SpoIIP PF07454.11 CDJ53531.1 - 2.4 7.5 25.0 0.63 9.5 2.7 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Peptidase_S49_N PF08496.10 CDJ53531.1 - 2.6 8.1 24.3 2.4 8.2 13.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CCSAP PF15748.5 CDJ53531.1 - 3.1 7.9 38.5 0.86 9.7 16.3 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated EOS1 PF12326.8 CDJ53531.1 - 3.2 7.7 14.2 1.2 9.0 2.2 2.3 2 0 0 2 2 2 0 N-glycosylation protein XAP5 PF04921.14 CDJ53531.1 - 3.7 7.3 14.8 4.6 7.0 4.6 2.3 2 0 0 2 2 2 0 XAP5, circadian clock regulator U1snRNP70_N PF12220.8 CDJ53531.1 - 3.9 8.2 21.4 3.1 8.5 3.1 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Dsh_C PF12316.8 CDJ53531.1 - 5.3 7.4 47.2 0.22 11.9 31.8 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Vfa1 PF08432.10 CDJ53531.1 - 7.1 6.9 25.5 1.6 9.1 2.4 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF966 PF06136.13 CDJ53531.1 - 7.4 6.2 35.9 0.26 11.0 17.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Peroxin-13_N PF04088.13 CDJ53531.1 - 8.2 6.7 16.1 3 8.1 5.5 2.5 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Mus7 PF09462.10 CDJ53531.1 - 8.3 5.1 16.2 7.8 5.2 0.1 2.0 2 0 0 2 2 2 0 Mus7/MMS22 family RNase_H2_suC PF08615.11 CDJ53531.1 - 8.6 6.5 14.0 5.4 7.2 1.0 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SLC12 PF03522.15 CDJ53531.1 - 9.3 5.1 23.5 2 7.3 3.3 2.0 2 0 0 2 2 2 0 Solute carrier family 12 DUF4471 PF14740.6 CDJ53531.1 - 9.7 5.3 15.5 9.9 5.3 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) SR-25 PF10500.9 CDJ53532.1 - 0.00012 21.8 8.2 0.00012 21.8 8.2 2.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein CcdA PF07362.12 CDJ53532.1 - 0.039 14.4 6.0 0.039 14.4 6.0 3.3 4 0 0 4 4 4 0 Post-segregation antitoxin CcdA IMUP PF15761.5 CDJ53532.1 - 0.66 10.7 12.1 0.072 13.8 7.3 1.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF3446 PF11928.8 CDJ53532.1 - 1.5 9.2 17.2 0.13 12.6 10.9 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Aquarius_N PF16399.5 CDJ53533.1 - 6.1e-69 233.0 21.1 2.3e-42 145.1 0.4 10.5 6 5 3 10 10 10 4 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 CDJ53533.1 - 2.9e-10 40.4 24.2 2.9e-10 40.4 24.2 5.8 4 2 1 5 5 5 1 AAA domain AAA_5 PF07728.14 CDJ53533.1 - 0.0018 18.3 0.0 0.0083 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CDJ53533.1 - 0.0066 16.2 0.9 0.0066 16.2 0.9 4.2 5 1 0 5 5 5 1 AAA domain AAA_18 PF13238.6 CDJ53533.1 - 0.023 15.3 5.2 0.031 14.8 0.0 3.8 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 CDJ53533.1 - 0.037 14.4 0.1 0.037 14.4 0.1 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NST1 PF13945.6 CDJ53534.1 - 0.0063 16.6 26.7 0.0063 16.6 26.7 2.4 2 0 0 2 2 2 1 Salt tolerance down-regulator RskA PF10099.9 CDJ53534.1 - 0.1 12.9 25.5 2.1 8.6 25.4 2.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Asparaginase_2 PF01112.18 CDJ53534.1 - 2.7 6.9 23.5 0.86 8.6 6.6 2.2 2 0 0 2 2 2 0 Asparaginase DUF572 PF04502.13 CDJ53534.1 - 5.7 6.5 43.8 9.6 5.7 43.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) AAA_12 PF13087.6 CDJ53535.1 - 1.6e-19 70.3 0.6 9e-15 54.8 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_11 PF13086.6 CDJ53535.1 - 2.8e-06 27.3 15.2 0.0029 17.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain Zip PF02535.22 CDJ53535.1 - 0.0046 16.2 1.8 0.0046 16.2 1.8 2.2 2 0 0 2 2 2 1 ZIP Zinc transporter PIP5K PF01504.18 CDJ53535.1 - 0.0057 15.9 1.3 0.0057 15.9 1.3 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase SAPS PF04499.15 CDJ53535.1 - 0.02 13.7 6.7 0.041 12.7 0.0 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Otopetrin PF03189.13 CDJ53535.1 - 0.032 13.1 0.0 0.057 12.2 0.0 1.5 1 1 0 1 1 1 0 Otopetrin Viral_helicase1 PF01443.18 CDJ53535.1 - 0.095 12.4 0.0 0.095 12.4 0.0 2.1 2 1 0 2 2 1 0 Viral (Superfamily 1) RNA helicase MecA PF05389.12 CDJ53535.1 - 0.25 10.9 0.0 0.25 10.9 0.0 3.1 3 1 0 3 3 2 0 Negative regulator of genetic competence (MecA) FAM60A PF15396.6 CDJ53535.1 - 1.1 9.3 11.2 0.22 11.5 4.1 2.3 2 0 0 2 2 2 0 Protein Family FAM60A CLN3 PF02487.17 CDJ53535.1 - 1.1 8.2 9.5 0.03 13.4 0.9 2.1 2 0 0 2 2 2 0 CLN3 protein Presenilin PF01080.17 CDJ53535.1 - 2.4 6.8 24.6 0.073 11.8 9.6 2.2 2 0 0 2 2 2 0 Presenilin RskA PF10099.9 CDJ53535.1 - 3.3 8.0 0.0 3.3 8.0 0.0 3.8 2 2 1 3 3 2 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ53536.1 - 0.032 14.5 10.9 0.045 14.0 10.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ53536.1 - 0.08 12.9 14.7 0.09 12.8 14.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Arabinose_Iso_C PF11762.8 CDJ53536.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain Spt20 PF12090.8 CDJ53536.1 - 3.8 7.1 17.1 5 6.7 17.1 1.1 1 0 0 1 1 1 0 Spt20 family STIMATE PF12400.8 CDJ53537.1 - 6.3e-32 110.8 3.4 7.4e-32 110.5 3.4 1.0 1 0 0 1 1 1 1 STIMATE family PAT1 PF09770.9 CDJ53538.1 - 5.3 5.2 49.1 7 4.8 49.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ53538.1 - 6.5 4.9 25.0 11 4.1 25.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DnaJ_C PF01556.18 CDJ53539.1 - 3.1e-35 121.4 0.1 4.8e-35 120.8 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ53539.1 - 5e-25 87.4 1.5 8.2e-25 86.7 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain TB PF00683.17 CDJ53539.1 - 0.024 14.4 0.2 0.044 13.5 0.2 1.4 1 0 0 1 1 1 0 TB domain DnaJ_CXXCXGXG PF00684.19 CDJ53539.1 - 0.18 12.2 3.6 0.33 11.3 3.6 1.4 1 0 0 1 1 1 0 DnaJ central domain Neur_chan_memb PF02932.16 CDJ53541.1 - 0.045 13.8 1.9 0.046 13.8 1.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region P5-ATPase PF12409.8 CDJ53541.1 - 0.061 13.4 0.6 0.088 12.9 0.6 1.1 1 0 0 1 1 1 0 P5-type ATPase cation transporter Zip PF02535.22 CDJ53541.1 - 0.063 12.5 0.7 0.074 12.3 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2828 PF11443.8 CDJ53541.1 - 0.087 10.9 6.6 0.091 10.8 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EOS1 PF12326.8 CDJ53541.1 - 0.11 12.4 0.9 0.15 12.0 0.9 1.2 1 0 0 1 1 1 0 N-glycosylation protein SelP_N PF04592.14 CDJ53541.1 - 0.43 9.9 15.1 0.57 9.5 15.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ctr PF04145.15 CDJ53541.1 - 0.73 10.4 5.8 1.2 9.7 5.8 1.4 1 1 0 1 1 1 0 Ctr copper transporter family CLN3 PF02487.17 CDJ53541.1 - 1.2 8.1 4.6 1.3 8.0 4.6 1.1 1 0 0 1 1 1 0 CLN3 protein Baculo_PP31 PF05311.11 CDJ53541.1 - 1.8 8.0 10.3 2.3 7.7 10.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Connexin PF00029.19 CDJ53541.1 - 3.5 7.3 8.7 4.1 7.1 8.7 1.2 1 0 0 1 1 1 0 Connexin SARAF PF06682.12 CDJ53541.1 - 4.7 6.8 20.3 14 5.2 20.3 1.7 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TORC_M PF12885.7 CDJ53541.1 - 4.7 7.1 8.4 5.7 6.8 8.4 1.1 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain PAT1 PF09770.9 CDJ53542.1 - 0.0024 16.2 26.8 0.0028 16.0 26.8 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 CDJ53542.1 - 0.047 13.7 41.3 0.062 13.3 41.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ53542.1 - 0.21 10.3 19.5 0.29 9.8 19.5 1.3 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 CDJ53542.1 - 0.27 9.6 4.5 0.34 9.3 4.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4647 PF15504.6 CDJ53542.1 - 0.32 10.1 20.2 0.42 9.7 20.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) CCSAP PF15748.5 CDJ53542.1 - 0.52 10.4 21.8 0.67 10.1 21.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF637 PF04830.13 CDJ53542.1 - 0.57 10.0 17.1 0.93 9.3 17.1 1.3 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) SLC12 PF03522.15 CDJ53542.1 - 0.64 9.0 15.8 0.81 8.6 15.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 UPF0560 PF10577.9 CDJ53542.1 - 0.78 8.2 18.2 1.1 7.7 18.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Zip PF02535.22 CDJ53542.1 - 0.96 8.6 7.6 1.2 8.2 7.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 CDJ53542.1 - 1 8.8 13.7 1.4 8.3 13.7 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Velvet PF11754.8 CDJ53542.1 - 1 9.3 14.4 1.6 8.6 14.4 1.4 1 0 0 1 1 1 0 Velvet factor Sin_N PF04801.13 CDJ53542.1 - 1.8 7.7 24.3 2.3 7.3 24.3 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region DUF3807 PF12720.7 CDJ53542.1 - 2.6 8.3 26.7 3.6 7.8 26.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF4746 PF15928.5 CDJ53542.1 - 2.6 7.4 12.0 3.4 7.0 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Serinc PF03348.15 CDJ53542.1 - 2.7 6.8 8.9 3.5 6.5 8.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DcuA_DcuB PF03605.14 CDJ53542.1 - 3.3 6.5 7.2 4.9 5.9 7.2 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter GREB1 PF15782.5 CDJ53542.1 - 3.6 4.6 20.2 4.3 4.3 20.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ53542.1 - 5.5 6.5 19.0 7.7 6.0 19.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PPL5 PF18168.1 CDJ53542.1 - 5.9 6.1 11.2 8 5.7 11.2 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Sec62 PF03839.16 CDJ53542.1 - 6.8 6.1 11.6 9.8 5.6 11.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 SAPS PF04499.15 CDJ53542.1 - 7.2 5.3 13.5 9 5.0 13.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.6 CDJ53542.1 - 7.5 5.2 16.5 9.7 4.8 16.5 1.1 1 0 0 1 1 1 0 Raftlin Exonuc_VII_L PF02601.15 CDJ53542.1 - 7.5 6.0 21.1 9.7 5.7 21.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SR-25 PF10500.9 CDJ53542.1 - 9.8 5.7 25.3 2.8 7.5 20.4 1.9 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein PA26 PF04636.13 CDJ53542.1 - 9.8 5.0 12.7 14 4.5 12.7 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RskA PF10099.9 CDJ53543.1 - 0.0079 16.5 34.7 0.0079 16.5 34.7 4.5 2 1 2 4 4 4 1 Anti-sigma-K factor rskA Peptidase_S49_N PF08496.10 CDJ53543.1 - 0.021 14.9 6.5 0.021 14.9 6.5 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF2828 PF11443.8 CDJ53543.1 - 0.13 10.3 17.1 0.22 9.6 17.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2052 PF09747.9 CDJ53543.1 - 0.22 11.6 21.8 0.45 10.6 21.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Heliorhodopsin PF18761.1 CDJ53543.1 - 0.33 10.2 2.1 0.43 9.8 0.0 2.1 2 0 0 2 2 2 0 Heliorhodopsin Hamartin PF04388.12 CDJ53543.1 - 2 7.0 24.9 2.3 6.8 24.9 1.1 1 0 0 1 1 1 0 Hamartin protein SLC12 PF03522.15 CDJ53543.1 - 2.9 6.8 25.6 4.4 6.2 25.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Rtf2 PF04641.12 CDJ53543.1 - 3.5 6.9 24.8 1.3 8.3 19.6 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger MecA PF05389.12 CDJ53543.1 - 3.6 7.2 23.2 0.093 12.4 5.4 2.6 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) PAT1 PF09770.9 CDJ53543.1 - 4.5 5.4 46.0 6.2 5.0 46.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ53544.1 - 0.0007 19.3 4.6 0.0007 19.3 4.6 10.7 6 1 5 11 11 11 4 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ53545.1 - 0.0012 18.6 33.8 0.0017 18.0 33.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Miga PF10265.9 CDJ53545.1 - 0.13 11.2 22.0 0.16 10.9 22.0 1.0 1 0 0 1 1 1 0 Mitoguardin OAD_gamma PF04277.13 CDJ53545.1 - 2.8 8.6 5.7 2.6 8.7 0.4 2.5 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Polyketide_cyc PF03364.20 CDJ53545.1 - 3 8.0 9.7 0.25 11.5 4.8 1.7 1 1 1 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport PPP4R2 PF09184.11 CDJ53545.1 - 4.5 6.8 27.0 5.2 6.6 27.0 1.0 1 0 0 1 1 1 0 PPP4R2 Macoilin PF09726.9 CDJ53545.1 - 6.8 5.1 31.6 8.2 4.8 31.6 1.1 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 CDJ53545.1 - 8.1 4.7 21.4 12 4.1 21.4 1.2 1 0 0 1 1 1 0 Menin SR-25 PF10500.9 CDJ53546.1 - 0.0094 15.6 29.4 0.013 15.1 29.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.13 CDJ53546.1 - 0.91 8.5 36.0 1.1 8.2 36.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4604 PF15377.6 CDJ53546.1 - 1.7 9.0 31.6 2 8.8 31.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Serinc PF03348.15 CDJ53546.1 - 2.6 6.9 21.6 3.5 6.4 21.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.6 CDJ53546.1 - 3.5 5.9 15.3 5.8 5.2 15.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 INCENP_ARK-bind PF03941.15 CDJ53547.1 - 2.9e-06 27.1 1.6 2.9e-06 27.1 1.6 6.7 6 0 0 6 6 6 1 Inner centromere protein, ARK binding region NIF PF03031.18 CDJ53548.1 - 4.7e-05 23.2 0.0 0.00019 21.2 0.0 1.9 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase RskA PF10099.9 CDJ53548.1 - 0.0091 16.3 9.6 0.0091 16.3 9.6 16.3 4 4 7 11 11 11 2 Anti-sigma-K factor rskA PDEase_I PF00233.19 CDJ53549.1 - 0.057 13.1 0.1 0.097 12.4 0.1 1.4 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase TFIIA PF03153.13 CDJ53550.1 - 9.5e-05 22.6 13.0 0.00012 22.3 13.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ53550.1 - 0.00036 20.9 11.7 0.00036 20.9 11.7 2.3 1 1 1 2 2 2 2 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ53550.1 - 0.013 14.4 11.1 0.028 13.4 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ53550.1 - 0.04 13.5 20.2 0.061 12.9 5.6 2.2 2 0 0 2 2 2 0 Spt20 family MAPEG PF01124.18 CDJ53550.1 - 1.1 9.1 6.4 3 7.8 6.4 1.9 1 1 0 1 1 1 0 MAPEG family DUF2188 PF09954.9 CDJ53550.1 - 1.5 9.0 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) SMAP PF15477.6 CDJ53550.1 - 5.8 7.9 9.9 1.3 10.1 1.4 2.4 2 0 0 2 2 2 0 Small acidic protein family Activator_LAG-3 PF11498.8 CDJ53550.1 - 7.6 5.4 29.0 1.5 7.7 5.9 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 GTP_EFTU PF00009.27 CDJ53551.1 - 3.7e-05 23.3 1.4 0.00076 19.1 1.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RNA_pol_Rpb5_C PF01191.19 CDJ53553.1 - 5.4e-34 115.9 0.3 1.2e-33 114.7 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CDJ53553.1 - 0.00013 22.5 0.0 0.00026 21.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 CDJ53553.1 - 0.00028 20.9 0.0 0.00041 20.4 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Tim54 PF11711.8 CDJ53555.1 - 0.0079 15.0 1.0 0.0079 15.0 1.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF4366 PF14283.6 CDJ53555.1 - 0.014 15.5 2.0 0.016 15.2 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4746 PF15928.5 CDJ53555.1 - 0.015 14.8 1.0 0.015 14.8 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TRAP_alpha PF03896.16 CDJ53555.1 - 0.03 13.5 0.3 0.032 13.5 0.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Spt20 PF12090.8 CDJ53555.1 - 0.049 13.2 5.3 0.058 13.0 5.3 1.2 1 0 0 1 1 1 0 Spt20 family FmdA_AmdA PF03069.15 CDJ53555.1 - 0.26 10.1 2.1 0.29 9.9 2.1 1.0 1 0 0 1 1 1 0 Acetamidase/Formamidase family DUF2076 PF09849.9 CDJ53555.1 - 1.1 9.3 14.7 1.4 9.0 14.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Roughex PF06020.11 CDJ53555.1 - 1.5 7.9 8.6 1.5 7.8 8.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Paf1 PF03985.13 CDJ53555.1 - 2.5 7.0 9.5 3 6.8 9.5 1.0 1 0 0 1 1 1 0 Paf1 TFIIA PF03153.13 CDJ53555.1 - 4.7 7.1 14.9 4.9 7.0 14.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit THOC2_N PF16134.5 CDJ53555.1 - 5 5.6 8.3 5.3 5.5 8.3 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Ribosomal_60s PF00428.19 CDJ53555.1 - 7.7 7.2 32.6 0.13 12.8 15.5 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein CCDC53 PF10152.9 CDJ53555.1 - 8.1 6.8 10.0 9.7 6.6 10.0 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Bromodomain PF00439.25 CDJ53556.1 - 1.9e-14 53.5 0.0 3.2e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain SUIM_assoc PF16619.5 CDJ53556.1 - 0.019 15.0 0.7 0.019 15.0 0.7 9.7 7 2 1 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 AP2 PF00847.20 CDJ53557.1 - 0.00082 19.6 3.1 0.00082 19.6 3.1 4.5 7 0 0 7 7 7 1 AP2 domain DUF4667 PF15700.5 CDJ53557.1 - 0.0092 16.1 3.3 0.0092 16.1 3.3 9.0 5 1 3 8 8 8 1 Domain of unknown function (DUF4667) Sulfotransfer_2 PF03567.14 CDJ53557.1 - 2.9 7.7 12.4 11 5.9 12.4 2.0 1 0 0 1 1 1 0 Sulfotransferase family NAM-associated PF14303.6 CDJ53557.1 - 7.6 7.2 0.0 7.6 7.2 0.0 9.3 7 4 2 9 9 9 0 No apical meristem-associated C-terminal domain AF-4 PF05110.13 CDJ53558.1 - 0.012 13.8 1.8 0.015 13.4 1.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SOBP PF15279.6 CDJ53558.1 - 0.65 10.6 9.0 0.92 10.1 9.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.17 CDJ53558.1 - 2 7.1 3.9 2.1 7.0 3.9 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ53559.1 - 0.01 15.9 6.4 0.012 15.7 6.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 CDJ53559.1 - 0.028 12.9 0.2 0.035 12.5 0.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hydin_ADK PF17213.3 CDJ53559.1 - 0.2 11.9 14.9 0.24 11.7 14.9 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain FAM70 PF14967.6 CDJ53559.1 - 0.29 10.6 8.4 0.4 10.1 8.4 1.3 1 0 0 1 1 1 0 FAM70 protein EOS1 PF12326.8 CDJ53559.1 - 0.74 9.7 4.4 1.2 9.1 4.4 1.4 1 1 0 1 1 1 0 N-glycosylation protein Pex24p PF06398.11 CDJ53559.1 - 0.96 8.4 3.5 1.5 7.7 2.3 1.4 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin SLC12 PF03522.15 CDJ53559.1 - 1.5 7.8 14.3 1.7 7.6 14.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 CDJ53559.1 - 5.7 6.1 15.9 9.9 5.3 15.9 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 CDJ53559.1 - 8.5 6.2 51.4 11 5.9 51.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CDJ53560.1 - 1e-42 146.4 0.0 5.1e-32 111.3 0.0 4.4 5 1 0 5 5 5 2 Protein kinase domain SR-25 PF10500.9 CDJ53560.1 - 0.001 18.8 6.3 0.001 18.8 6.3 10.1 7 2 4 11 11 11 2 Nuclear RNA-splicing-associated protein Glycolytic PF00274.19 CDJ53561.1 - 8.9e-168 557.4 0.0 1e-167 557.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Rad10 PF03834.14 CDJ53562.1 - 3.5e-25 88.2 0.0 6e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH PF00633.23 CDJ53562.1 - 0.00034 20.3 0.0 0.00078 19.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 CDJ53562.1 - 0.0066 16.5 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Zip PF02535.22 CDJ53562.1 - 0.0092 15.2 0.2 0.011 14.9 0.2 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Connexin PF00029.19 CDJ53562.1 - 0.015 15.0 0.7 0.025 14.4 0.7 1.3 1 0 0 1 1 1 0 Connexin Tim54 PF11711.8 CDJ53562.1 - 0.069 11.9 7.2 0.11 11.2 7.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EPL1 PF10513.9 CDJ53562.1 - 0.07 13.5 9.7 0.14 12.6 9.7 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like OATP PF03137.20 CDJ53562.1 - 0.22 9.8 4.1 0.35 9.1 4.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SpoIIP PF07454.11 CDJ53562.1 - 0.5 9.8 11.3 0.8 9.1 11.3 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Peptidase_S49_N PF08496.10 CDJ53562.1 - 0.64 10.1 7.3 1.4 9.0 7.3 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CLN3 PF02487.17 CDJ53562.1 - 1 8.4 6.1 1.6 7.7 6.1 1.3 1 0 0 1 1 1 0 CLN3 protein FAM60A PF15396.6 CDJ53562.1 - 2.1 8.3 7.3 4.7 7.2 7.3 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Med1 PF10744.9 CDJ53562.1 - 2.7 6.9 13.8 4 6.4 13.8 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 DUF2877 PF11392.8 CDJ53562.1 - 2.8 8.7 5.5 11 6.7 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2877) DUF4770 PF15994.5 CDJ53562.1 - 3.6 7.8 16.7 7.3 6.8 16.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FAM222A PF15258.6 CDJ53562.1 - 4 6.4 30.3 7 5.6 30.3 1.3 1 0 0 1 1 1 0 Protein family of FAM222A Endostatin PF06482.11 CDJ53562.1 - 4.3 6.7 16.6 7.7 5.9 16.6 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Gti1_Pac2 PF09729.9 CDJ53562.1 - 8 6.5 10.6 16 5.5 10.6 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family Plasmodium_Vir PF05795.11 CDJ53562.1 - 9.1 5.6 5.4 16 4.8 5.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Thioredoxin PF00085.20 CDJ53563.1 - 0.00081 19.3 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CDJ53563.1 - 0.0085 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain PIG-U PF06728.13 CDJ53563.1 - 0.043 12.9 0.0 0.057 12.5 0.0 1.1 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U ketoacyl-synt PF00109.26 CDJ53564.1 - 0 1006.6 7.6 7e-79 265.0 0.5 4.9 4 0 0 4 4 4 4 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 CDJ53564.1 - 1.1e-238 784.5 0.0 2.6e-58 196.9 0.0 5.8 5 0 0 5 5 5 4 KR domain PS-DH PF14765.6 CDJ53564.1 - 1.9e-166 552.7 14.5 2.5e-43 148.4 1.3 5.4 5 0 0 5 5 5 5 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CDJ53564.1 - 8e-165 538.7 8.2 6.8e-41 139.0 0.3 5.0 5 0 0 5 5 4 4 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 CDJ53564.1 - 3.7e-118 394.7 4.8 7.5e-47 160.4 0.2 3.4 3 0 0 3 3 3 3 Acyl transferase domain AMP-binding PF00501.28 CDJ53564.1 - 3.7e-73 246.5 0.0 8.3e-73 245.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CDJ53564.1 - 2.7e-68 226.3 2.8 1e-12 48.2 0.0 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 CDJ53564.1 - 1.2e-53 180.6 0.4 3e-13 49.9 0.0 5.1 4 0 0 4 4 4 4 Zinc-binding dehydrogenase NAD_binding_4 PF07993.12 CDJ53564.1 - 2.2e-51 174.5 0.0 8.9e-48 162.7 0.0 4.5 5 0 0 5 5 5 1 Male sterility protein adh_short PF00106.25 CDJ53564.1 - 1.6e-48 164.8 3.3 2.2e-11 43.6 0.0 6.1 7 0 0 7 7 6 4 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 CDJ53564.1 - 2e-42 145.4 0.0 3e-09 38.0 0.0 6.0 5 0 0 5 5 5 4 Zinc-binding dehydrogenase Sulfotransfer_3 PF13469.6 CDJ53564.1 - 2.3e-42 145.8 0.1 5e-42 144.7 0.1 1.6 1 0 0 1 1 1 1 Sulfotransferase family KAsynt_C_assoc PF16197.5 CDJ53564.1 - 2.3e-34 118.2 0.0 1.6e-08 34.9 0.0 4.8 4 0 0 4 4 4 4 Ketoacyl-synthetase C-terminal extension adh_short_C2 PF13561.6 CDJ53564.1 - 4.4e-33 114.8 0.0 9.1e-08 31.9 0.0 4.9 4 0 0 4 4 4 4 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CDJ53564.1 - 9e-32 110.4 0.0 4e-07 29.7 0.0 5.5 5 0 0 5 5 5 5 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 CDJ53564.1 - 8e-22 77.2 17.8 3.4e-05 23.7 0.1 6.5 6 1 0 6 6 5 4 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 CDJ53564.1 - 1.9e-17 63.5 8.6 0.0019 17.6 0.2 5.0 4 0 0 4 4 4 4 Thiolase, N-terminal domain Sulfotransfer_1 PF00685.27 CDJ53564.1 - 4.1e-15 56.0 0.3 7.5e-15 55.1 0.3 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Polysacc_synt_2 PF02719.15 CDJ53564.1 - 4.4e-15 55.6 0.0 0.019 14.1 0.0 4.9 5 0 0 5 5 5 4 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CDJ53564.1 - 7.3e-13 48.1 0.0 0.2 10.6 0.0 5.5 5 0 0 5 5 5 4 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CDJ53564.1 - 4.3e-10 39.5 0.0 0.065 12.6 0.0 5.4 5 0 0 5 5 5 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CDJ53564.1 - 0.0014 18.6 0.1 20 5.0 0.1 4.8 4 0 0 4 4 4 0 NAD(P)H-binding AMP-binding_C_2 PF14535.6 CDJ53564.1 - 0.0017 18.6 0.0 0.0055 17.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AlaDh_PNT_C PF01262.21 CDJ53564.1 - 0.0028 17.0 16.9 0.36 10.1 0.4 4.6 4 0 0 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 CDJ53564.1 - 0.0032 17.1 1.2 6.6 6.4 0.4 4.6 4 0 0 4 4 4 0 Ketopantoate reductase PanE/ApbA ACP_syn_III PF08545.10 CDJ53564.1 - 0.013 15.3 21.7 1.1 9.2 0.6 5.7 4 1 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sulfotransfer_4 PF17784.1 CDJ53564.1 - 0.017 15.0 0.4 0.075 12.8 0.1 2.3 2 0 0 2 2 2 0 Sulfotransferase domain SAT PF16073.5 CDJ53564.1 - 0.062 13.0 8.8 0.47 10.1 0.2 4.1 3 2 0 3 3 3 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Shikimate_DH PF01488.20 CDJ53564.1 - 0.08 13.0 0.9 54 3.8 0.0 3.7 4 0 0 4 4 3 0 Shikimate / quinate 5-dehydrogenase IMCp PF12314.8 CDJ53565.1 - 3.5e-25 88.1 60.4 1.6e-24 86.0 39.8 4.7 2 2 1 3 3 3 2 Inner membrane complex protein IMCp PF12314.8 CDJ53566.1 - 5.1e-30 103.6 90.5 5e-19 68.4 38.3 4.3 1 1 1 3 3 3 3 Inner membrane complex protein LSM PF01423.22 CDJ53567.1 - 6.6e-16 57.8 0.7 1.2e-15 56.9 0.7 1.4 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDJ53567.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Hfq protein RRM_1 PF00076.22 CDJ53568.1 - 7.6e-08 32.1 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AT_hook PF02178.19 CDJ53569.1 - 0.39 10.7 3.7 1.1 9.4 3.7 1.8 1 0 0 1 1 1 0 AT hook motif Nucleoside_tran PF01733.18 CDJ53570.1 - 2.8e-15 56.5 11.3 4.7e-15 55.8 11.3 1.3 1 0 0 1 1 1 1 Nucleoside transporter EMP24_GP25L PF01105.24 CDJ53570.1 - 0.19 11.6 0.9 0.45 10.4 0.9 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FXa_inhibition PF14670.6 CDJ53572.1 - 0.026 14.8 4.7 0.026 14.8 4.7 6.6 5 1 1 6 6 6 0 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CDJ53572.1 - 0.063 13.9 1.0 0.063 13.9 1.0 8.3 7 1 0 8 8 8 0 Human growth factor-like EGF Corona_nucleoca PF00937.18 CDJ53572.1 - 0.068 12.2 1.8 0.11 11.6 1.8 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein EGF_3 PF12947.7 CDJ53572.1 - 0.11 12.7 56.9 0.035 14.3 10.1 6.8 5 2 1 6 6 6 0 EGF domain EGF PF00008.27 CDJ53572.1 - 1.8 9.0 70.0 2.7 8.4 5.6 7.6 6 4 0 6 6 6 0 EGF-like domain SUIM_assoc PF16619.5 CDJ53573.1 - 0.0019 18.2 1.5 0.0019 18.2 1.5 9.6 8 3 0 8 8 8 2 Unstructured region C-term to UIM in Ataxin3 zf-CCCH PF00642.24 CDJ53573.1 - 0.012 15.5 0.7 0.025 14.5 0.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ53573.1 - 0.23 11.3 0.9 0.45 10.4 0.9 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger SR-25 PF10500.9 CDJ53577.1 - 0.0016 18.1 6.1 0.0016 18.1 6.1 5.7 4 2 2 6 6 6 1 Nuclear RNA-splicing-associated protein FAM60A PF15396.6 CDJ53578.1 - 0.021 14.8 8.7 0.026 14.5 8.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A V_ATPase_I PF01496.19 CDJ53578.1 - 0.039 11.9 14.3 0.048 11.6 14.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ53578.1 - 0.067 11.9 17.0 0.074 11.8 17.0 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ53578.1 - 0.29 10.1 15.1 0.33 9.9 15.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Serinc PF03348.15 CDJ53578.1 - 0.31 9.9 10.9 0.38 9.6 10.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) O-antigen_lig PF13425.6 CDJ53578.1 - 0.47 9.2 1.4 0.47 9.2 1.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Connexin PF00029.19 CDJ53578.1 - 0.76 9.5 11.0 0.98 9.1 11.0 1.3 1 0 0 1 1 1 0 Connexin DDHD PF02862.17 CDJ53578.1 - 0.84 9.8 13.2 1.2 9.3 13.2 1.3 1 0 0 1 1 1 0 DDHD domain Otopetrin PF03189.13 CDJ53578.1 - 0.88 8.3 4.9 1 8.1 4.9 1.2 1 0 0 1 1 1 0 Otopetrin DUF3984 PF13136.6 CDJ53578.1 - 1 8.7 21.6 1.2 8.4 21.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) OATP PF03137.20 CDJ53578.1 - 1.3 7.3 5.7 1.5 7.0 5.7 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PSK PF06404.12 CDJ53578.1 - 1.7 9.7 16.4 3.3 8.8 14.2 2.2 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) Hid1 PF12722.7 CDJ53578.1 - 2 6.4 15.4 2.3 6.3 15.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.6 CDJ53578.1 - 2.1 6.7 4.9 2.3 6.5 4.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ53578.1 - 2.2 8.3 14.3 2.6 8.1 14.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.12 CDJ53578.1 - 2.5 7.4 23.5 3 7.2 23.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 CDJ53578.1 - 3.5 7.4 17.7 4.1 7.2 17.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 CDJ53578.1 - 3.9 6.7 14.2 5.2 6.3 14.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SLC12 PF03522.15 CDJ53578.1 - 5.1 6.0 16.7 6 5.8 16.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CLN3 PF02487.17 CDJ53578.1 - 5.3 6.0 11.0 6.3 5.7 11.0 1.2 1 0 0 1 1 1 0 CLN3 protein MDM31_MDM32 PF08118.11 CDJ53578.1 - 5.4 5.6 8.1 6.3 5.3 8.1 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins NPR3 PF03666.13 CDJ53578.1 - 5.8 5.6 16.2 7.2 5.3 16.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MAJIN PF15077.6 CDJ53578.1 - 9.8 5.9 12.5 11 5.7 12.5 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein SARAF PF06682.12 CDJ53579.1 - 0.047 13.4 0.3 0.072 12.7 0.3 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 CDJ53579.1 - 0.083 13.9 0.2 0.14 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ53579.1 - 0.33 10.5 10.9 0.5 10.0 10.9 1.2 1 0 0 1 1 1 0 Spt20 family Conotoxin PF02950.17 CDJ53579.1 - 0.79 10.8 6.7 5.5 8.1 0.2 3.4 3 0 0 3 3 3 0 Conotoxin DUF2722 PF10846.8 CDJ53579.1 - 1.2 8.0 8.9 1.7 7.5 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Macro PF01661.21 CDJ53580.1 - 0.002 18.2 0.0 0.002 18.2 0.0 4.2 4 0 0 4 4 4 1 Macro domain TERB2 PF15101.6 CDJ53580.1 - 0.0061 16.6 3.1 0.0061 16.6 3.1 16.5 13 5 5 18 18 18 1 Telomere-associated protein TERB2 RskA PF10099.9 CDJ53580.1 - 0.0065 16.8 0.0 0.0065 16.8 0.0 20.0 5 5 11 16 16 16 4 Anti-sigma-K factor rskA O-antigen_lig PF13425.6 CDJ53581.1 - 0.18 10.6 3.7 0.22 10.3 3.7 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SLATT_6 PF18169.1 CDJ53581.1 - 0.4 10.3 3.5 0.58 9.7 3.5 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 EMC3_TMCO1 PF01956.16 CDJ53581.1 - 0.59 9.8 11.4 0.88 9.3 11.4 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Connexin PF00029.19 CDJ53581.1 - 0.6 9.8 3.4 0.79 9.4 3.4 1.2 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 CDJ53581.1 - 1.4 7.8 2.9 1.6 7.6 2.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CSG2 PF16965.5 CDJ53581.1 - 1.5 7.7 2.9 1.7 7.5 2.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator CLN3 PF02487.17 CDJ53581.1 - 2.9 6.9 5.3 4.1 6.4 5.3 1.2 1 0 0 1 1 1 0 CLN3 protein DUF3533 PF12051.8 CDJ53581.1 - 6.7 5.5 10.9 13 4.6 10.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Asp-B-Hydro_N PF05279.11 CDJ53582.1 - 6.2 6.8 19.4 8.8 6.3 19.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Spt20 PF12090.8 CDJ53583.1 - 0.0018 17.9 3.2 0.0018 17.9 3.2 3.9 3 1 1 4 4 4 2 Spt20 family RskA PF10099.9 CDJ53583.1 - 0.0021 18.4 13.4 0.0021 18.4 13.4 4.3 3 1 0 4 4 4 1 Anti-sigma-K factor rskA Npa1 PF11707.8 CDJ53583.1 - 0.0024 17.3 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal SR-25 PF10500.9 CDJ53583.1 - 0.012 15.3 14.8 0.012 15.3 14.8 4.2 5 0 0 5 5 5 0 Nuclear RNA-splicing-associated protein dsDNA_bind PF01984.20 CDJ53583.1 - 0.028 14.7 20.5 0.94 9.8 4.2 3.6 3 0 0 3 3 3 0 Double-stranded DNA-binding domain DUF1645 PF07816.11 CDJ53583.1 - 0.028 15.0 24.4 0.091 13.3 2.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1645) DUF2722 PF10846.8 CDJ53583.1 - 0.42 9.5 33.6 0.089 11.7 4.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) Phostensin_N PF13916.6 CDJ53583.1 - 3.4 8.1 23.2 1.7 9.0 0.1 4.3 4 0 0 4 4 4 0 PP1-regulatory protein, Phostensin N-terminal DUF4834 PF16118.5 CDJ53584.1 - 0.032 15.2 0.4 0.032 15.2 0.4 6.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4834) UCH PF00443.29 CDJ53584.1 - 0.15 11.5 25.7 0.46 9.9 0.0 3.5 3 1 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S8e PF01201.22 CDJ53585.1 - 5.9e-09 36.2 0.1 2.6e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S8e TraT PF05818.12 CDJ53585.1 - 0.85 9.3 5.1 0.75 9.4 3.9 1.5 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF192 PF02643.15 CDJ53586.1 - 1.3e-05 25.3 0.0 2.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 DUF2722 PF10846.8 CDJ53586.1 - 0.0023 17.0 2.1 0.0023 17.0 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ53586.1 - 0.012 15.2 9.1 0.016 14.8 9.1 1.2 1 0 0 1 1 1 0 Spt20 family Rhomboid PF01694.22 CDJ53587.1 - 3.8e-22 78.9 1.2 8.1e-22 77.8 1.2 1.5 1 0 0 1 1 1 1 Rhomboid family DUF4518 PF15008.6 CDJ53587.1 - 0.0032 16.7 2.9 0.0053 16.0 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) DcuA_DcuB PF03605.14 CDJ53587.1 - 0.0039 16.1 0.1 0.0039 16.1 0.1 1.7 2 0 0 2 2 1 1 Anaerobic c4-dicarboxylate membrane transporter SARAF PF06682.12 CDJ53587.1 - 0.0042 16.8 0.2 0.009 15.7 0.2 1.5 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis FHIPEP PF00771.20 CDJ53587.1 - 0.0062 15.1 1.5 0.0086 14.6 1.5 1.1 1 0 0 1 1 1 1 FHIPEP family DUF3169 PF11368.8 CDJ53587.1 - 0.0088 15.6 0.1 0.019 14.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) Orf78 PF06024.12 CDJ53587.1 - 0.0095 16.2 1.2 0.5 10.7 1.8 2.6 2 0 0 2 2 2 1 Orf78 (ac78) DUF4834 PF16118.5 CDJ53587.1 - 0.01 16.8 2.9 0.038 14.9 2.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Peroxin-13_N PF04088.13 CDJ53587.1 - 0.019 15.2 0.8 0.037 14.3 0.8 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region GWT1 PF06423.12 CDJ53587.1 - 0.021 14.9 0.2 0.1 12.7 0.1 2.1 2 0 0 2 2 2 0 GWT1 O-antigen_lig PF13425.6 CDJ53587.1 - 0.076 11.8 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ORC5_C PF14630.6 CDJ53587.1 - 0.094 12.2 1.4 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus UPF0239 PF06783.11 CDJ53587.1 - 0.1 12.8 1.9 0.37 11.0 1.3 2.3 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0239) PSK PF06404.12 CDJ53587.1 - 0.12 13.4 3.5 0.26 12.3 3.5 1.6 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) Dpy19 PF10034.9 CDJ53587.1 - 0.13 10.5 3.5 0.2 9.8 3.5 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation RasGEF_N PF00618.20 CDJ53587.1 - 0.13 12.5 0.3 0.33 11.2 0.3 1.7 1 0 0 1 1 1 0 RasGEF N-terminal motif PigN PF04987.14 CDJ53587.1 - 0.13 11.1 4.3 0.26 10.1 4.3 1.4 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF2227 PF09988.9 CDJ53587.1 - 0.14 12.0 0.7 0.44 10.4 0.7 1.8 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) Wzy_C PF04932.15 CDJ53587.1 - 0.14 11.8 0.0 0.75 9.4 0.0 2.1 2 0 0 2 2 2 0 O-Antigen ligase CRA PF06589.11 CDJ53587.1 - 0.15 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF3487 PF11990.8 CDJ53587.1 - 0.19 11.6 0.8 0.32 10.9 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF3487) Presenilin PF01080.17 CDJ53587.1 - 0.24 10.1 2.9 0.49 9.1 2.9 1.4 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 CDJ53587.1 - 0.37 9.8 7.5 0.59 9.1 4.7 2.4 2 1 0 2 2 2 0 CLN3 protein TMEM208_SND2 PF05620.11 CDJ53587.1 - 0.43 10.3 3.9 1.5 8.6 3.9 2.0 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF2722 PF10846.8 CDJ53587.1 - 0.56 9.1 20.3 0.016 14.2 14.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) EIIBC-GUT_N PF03612.14 CDJ53587.1 - 0.66 9.7 4.0 1.1 8.9 4.0 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RAMP4 PF06624.12 CDJ53587.1 - 1.1 9.4 4.3 0.97 9.6 1.9 2.2 2 0 0 2 2 1 0 Ribosome associated membrane protein RAMP4 PepSY_TM PF03929.16 CDJ53587.1 - 1.1 8.8 3.3 8.8 5.9 0.4 2.5 2 0 0 2 2 2 0 PepSY-associated TM region EphA2_TM PF14575.6 CDJ53587.1 - 3 8.8 6.5 1.4 9.9 2.9 2.3 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain TFIIA PF03153.13 CDJ53587.1 - 4.4 7.2 32.9 0.39 10.7 19.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3619 PF12279.8 CDJ53587.1 - 5.6 7.3 9.3 1.7 9.0 0.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3619) DivIC PF04977.15 CDJ53587.1 - 8.2 6.3 16.2 16 5.4 16.2 1.5 1 0 0 1 1 1 0 Septum formation initiator Conotoxin PF02950.17 CDJ53587.1 - 8.5 7.5 6.4 10 7.2 4.7 2.1 1 1 0 1 1 1 0 Conotoxin Hox9_act PF04617.13 CDJ53590.1 - 0.03 15.1 1.2 0.046 14.5 0.2 1.8 2 0 0 2 2 2 0 Hox9 activation region PT PF04886.12 CDJ53592.1 - 1.4 8.5 13.6 0.059 12.9 5.1 2.3 2 0 0 2 2 2 0 PT repeat RskA PF10099.9 CDJ53592.1 - 3.8 7.8 20.0 4.1 7.7 12.9 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ53593.1 - 0.47 10.4 17.2 0.62 10.0 17.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TRAPP PF04051.16 CDJ53594.1 - 4.7e-32 110.7 0.0 5.5e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component TFIIF_alpha PF05793.12 CDJ53595.1 - 0.00013 20.7 31.5 0.00018 20.3 31.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 CDJ53595.1 - 0.0017 16.7 18.1 0.0021 16.5 18.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Borrelia_P83 PF05262.11 CDJ53595.1 - 0.025 13.1 7.7 0.027 13.0 7.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SDA1 PF05285.12 CDJ53595.1 - 0.026 13.9 22.5 0.036 13.5 22.5 1.1 1 0 0 1 1 1 0 SDA1 Macoilin PF09726.9 CDJ53595.1 - 0.15 10.6 19.4 0.19 10.2 19.4 1.1 1 0 0 1 1 1 0 Macoilin family RRM_1 PF00076.22 CDJ53595.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.19 CDJ53595.1 - 0.4 10.5 31.0 0.56 10.1 31.0 1.2 1 0 0 1 1 1 0 SPX domain GREB1 PF15782.5 CDJ53595.1 - 0.61 7.1 22.8 0.76 6.8 22.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ53595.1 - 1.2 7.4 22.7 1.5 7.0 22.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.11 CDJ53595.1 - 1.5 8.9 18.8 2.1 8.4 18.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF572 PF04502.13 CDJ53595.1 - 1.5 8.4 20.3 2 7.9 20.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ALMT PF11744.8 CDJ53595.1 - 3 6.6 11.7 4.2 6.1 11.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ53595.1 - 4 6.3 19.3 5.4 5.9 19.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 CDJ53595.1 - 5.7 6.1 10.0 8.2 5.5 10.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 CDJ53595.1 - 9.3 5.6 18.7 13 5.1 18.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PNISR PF15996.5 CDJ53595.1 - 9.6 6.4 36.1 96 3.2 36.2 2.0 1 1 0 1 1 1 0 Arginine/serine-rich protein PNISR SPRY PF00622.28 CDJ53596.1 - 0.0004 20.5 0.0 0.0004 20.5 0.0 3.1 3 0 0 3 3 3 1 SPRY domain EMP24_GP25L PF01105.24 CDJ53597.1 - 6.3e-30 104.5 0.0 7.5e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Fig1 PF12351.8 CDJ53597.1 - 0.28 11.1 2.5 8.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 BRF1 PF07741.13 CDJ53598.1 - 0.0076 16.6 3.4 0.011 16.1 3.4 1.3 1 0 0 1 1 1 1 Brf1-like TBP-binding domain DUF4718 PF15842.5 CDJ53598.1 - 0.0089 15.8 15.5 0.0089 15.8 15.5 2.0 1 1 1 2 2 1 1 Domain of unknown function (DUF4718) TFIIA PF03153.13 CDJ53598.1 - 0.011 15.8 26.4 0.012 15.6 26.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ53598.1 - 0.022 14.2 7.4 0.023 14.2 7.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Plasmodium_Vir PF05795.11 CDJ53598.1 - 0.025 14.0 11.1 0.028 13.9 11.1 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein V_ATPase_I PF01496.19 CDJ53598.1 - 0.038 11.9 5.5 0.037 12.0 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CPSF100_C PF13299.6 CDJ53598.1 - 0.041 14.1 6.6 0.049 13.8 6.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Lin-8 PF03353.15 CDJ53598.1 - 0.053 13.1 19.8 0.065 12.8 19.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Paf1 PF03985.13 CDJ53598.1 - 0.057 12.4 10.3 0.062 12.3 10.3 1.1 1 0 0 1 1 1 0 Paf1 DUF2722 PF10846.8 CDJ53598.1 - 0.073 12.0 30.0 0.099 11.6 30.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MPM1 PF17234.2 CDJ53598.1 - 0.11 12.7 10.5 0.16 12.2 10.5 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF4175 PF13779.6 CDJ53598.1 - 0.14 10.0 22.4 0.16 9.8 22.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.9 CDJ53598.1 - 0.19 10.0 14.5 0.19 10.0 14.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ53598.1 - 0.19 11.8 8.9 0.21 11.6 8.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0560 PF10577.9 CDJ53598.1 - 0.2 10.1 18.0 0.24 9.9 18.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CobT PF06213.12 CDJ53598.1 - 0.21 11.0 14.8 0.23 10.8 14.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Connexin PF00029.19 CDJ53598.1 - 0.4 10.4 4.6 0.47 10.2 4.6 1.1 1 0 0 1 1 1 0 Connexin DUF3807 PF12720.7 CDJ53598.1 - 0.46 10.7 15.0 0.65 10.2 15.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Folate_carrier PF01770.18 CDJ53598.1 - 0.52 9.0 3.7 0.55 8.9 3.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier Tim54 PF11711.8 CDJ53598.1 - 0.52 9.0 6.1 0.54 9.0 6.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4551 PF15087.6 CDJ53598.1 - 0.67 8.7 17.3 0.75 8.6 17.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SLC12 PF03522.15 CDJ53598.1 - 0.83 8.6 12.6 0.92 8.5 12.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 TMEM51 PF15345.6 CDJ53598.1 - 0.99 9.2 14.5 1.4 8.7 14.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 GREB1 PF15782.5 CDJ53598.1 - 1.7 5.6 20.3 1.8 5.5 20.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Coilin_N PF15862.5 CDJ53598.1 - 2.1 8.2 15.1 0.11 12.3 9.4 1.6 2 0 0 2 2 2 0 Coilin N-terminus DUF4407 PF14362.6 CDJ53598.1 - 2.2 7.5 12.1 2.9 7.2 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3464 PF11947.8 CDJ53598.1 - 2.5 7.8 9.1 4.1 7.2 9.1 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 G0-G1_switch_2 PF15103.6 CDJ53598.1 - 3.3 8.2 8.5 5.3 7.5 8.5 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 SPX PF03105.19 CDJ53598.1 - 3.6 7.4 20.3 4.1 7.2 20.3 1.0 1 0 0 1 1 1 0 SPX domain ALMT PF11744.8 CDJ53598.1 - 3.6 6.3 12.1 4 6.1 12.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 CDJ53598.1 - 4.3 6.0 16.8 5.1 5.8 16.8 1.1 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 CDJ53598.1 - 4.9 7.5 9.3 0.54 10.6 4.7 1.7 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Cellulose_synt PF03552.14 CDJ53598.1 - 8.6 4.7 6.3 8.8 4.7 6.3 1.0 1 0 0 1 1 1 0 Cellulose synthase CCDC53 PF10152.9 CDJ53598.1 - 10 6.6 15.4 13 6.2 15.2 1.3 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex zf_CCCH_4 PF18345.1 CDJ53599.1 - 1.2e-10 41.1 20.8 2.3e-05 24.3 2.9 4.4 4 0 0 4 4 4 3 Zinc finger domain zf-CCCH PF00642.24 CDJ53599.1 - 2.2e-10 40.2 16.8 1.4e-07 31.2 2.1 3.9 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SUIM_assoc PF16619.5 CDJ53599.1 - 1.2e-05 25.2 1.8 1.2e-05 25.2 1.8 12.7 5 2 2 7 7 7 2 Unstructured region C-term to UIM in Ataxin3 zf-CCCH_4 PF18044.1 CDJ53599.1 - 0.0022 17.7 2.1 0.0022 17.7 2.1 3.7 3 0 0 3 3 3 1 CCCH-type zinc finger DUF2722 PF10846.8 CDJ53602.1 - 0.0041 16.1 0.5 0.0041 16.1 0.5 19.2 11 7 3 15 15 15 3 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ53602.1 - 0.039 14.3 0.1 0.039 14.3 0.1 22.7 10 7 9 20 20 20 0 Anti-sigma-K factor rskA WD40 PF00400.32 CDJ53603.1 - 6.6e-05 23.6 0.9 0.014 16.3 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ53603.1 - 0.00013 22.2 0.0 0.0042 17.3 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RskA PF10099.9 CDJ53603.1 - 0.0027 18.0 7.9 0.0027 18.0 7.9 10.4 4 2 3 7 7 7 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ53603.1 - 0.0056 16.7 19.2 0.0056 16.7 19.2 5.9 3 2 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ53604.1 - 6.7 6.2 17.3 10 5.7 17.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ53605.1 - 0.0073 15.9 11.9 0.0073 15.9 11.9 7.3 3 1 2 5 5 5 2 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 CDJ53606.1 - 0.0022 16.6 39.2 0.0032 16.1 39.2 1.2 1 0 0 1 1 1 1 Macoilin family TFIIF_alpha PF05793.12 CDJ53606.1 - 0.004 15.8 26.0 0.0064 15.1 26.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Caldesmon PF02029.15 CDJ53606.1 - 0.0066 15.3 33.0 0.008 15.0 33.0 1.1 1 0 0 1 1 1 1 Caldesmon AF-4 PF05110.13 CDJ53606.1 - 0.65 8.0 51.4 0.82 7.7 51.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SOBP PF15279.6 CDJ53606.1 - 0.91 10.1 33.6 1.2 9.7 33.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SR-25 PF10500.9 CDJ53606.1 - 1 8.9 51.4 1.8 8.1 11.1 2.9 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein Dapper PF15268.6 CDJ53606.1 - 2 7.2 49.6 2.3 7.0 49.6 1.0 1 0 0 1 1 1 0 Dapper LAP1C PF05609.12 CDJ53606.1 - 5.2 6.0 40.2 7.2 5.6 40.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PAT1 PF09770.9 CDJ53606.1 - 7.9 4.6 57.6 9.5 4.3 57.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.11 CDJ53606.1 - 9.7 4.5 42.6 12 4.2 42.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.13 CDJ53607.1 - 0.53 10.2 29.4 0.089 12.8 25.8 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cyt_bd_oxida_II PF02322.15 CDJ53607.1 - 4.5 6.6 10.5 6 6.1 0.4 2.1 1 1 1 2 2 2 0 Cytochrome bd terminal oxidase subunit II DUF844 PF05815.11 CDJ53607.1 - 4.7 6.3 8.7 2.2 7.4 6.5 1.5 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Ribosomal_60s PF00428.19 CDJ53608.1 - 0.56 10.8 5.6 0.61 10.7 0.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Band_3_cyto PF07565.13 CDJ53608.1 - 1.5 8.5 39.0 0.084 12.7 18.7 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Ferrochelatase PF00762.19 CDJ53609.1 - 2.8e-21 75.9 14.9 8.4e-14 51.4 0.5 3.5 1 1 2 3 3 3 2 Ferrochelatase RskA PF10099.9 CDJ53609.1 - 3.2e-05 24.3 30.4 0.00061 20.1 1.7 3.2 3 0 0 3 3 3 3 Anti-sigma-K factor rskA SecY PF00344.20 CDJ53609.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 SecY translocase Adaptin_binding PF10199.9 CDJ53609.1 - 2.8 8.6 20.5 2.9e+02 2.1 20.5 2.8 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 AAA_23 PF13476.6 CDJ53609.1 - 3.9 7.9 28.2 1.2e+03 -0.2 28.2 2.3 1 1 0 1 1 1 0 AAA domain DUF755 PF05501.11 CDJ53610.1 - 0.00047 20.4 18.0 0.00055 20.2 18.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF755) HutP PF09021.11 CDJ53610.1 - 0.018 15.4 2.1 0.02 15.2 2.1 1.1 1 0 0 1 1 1 0 HutP SR-25 PF10500.9 CDJ53610.1 - 0.14 11.8 18.6 0.21 11.2 18.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ53610.1 - 0.18 11.4 20.1 0.21 11.2 20.1 1.0 1 0 0 1 1 1 0 Spt20 family DUF702 PF05142.12 CDJ53610.1 - 0.26 11.8 9.9 0.3 11.6 9.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF2722 PF10846.8 CDJ53610.1 - 0.58 9.0 15.4 0.85 8.5 15.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NST1 PF13945.6 CDJ53610.1 - 1.1 9.4 15.6 1.2 9.2 15.6 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4692 PF15763.5 CDJ53610.1 - 1.2 9.6 7.0 1.4 9.4 7.0 1.0 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Kinesin_assoc PF16183.5 CDJ53610.1 - 1.6 8.9 3.4 1.7 8.8 3.4 1.1 1 0 0 1 1 1 0 Kinesin-associated MPM1 PF17234.2 CDJ53610.1 - 1.8 8.8 9.6 2.1 8.6 9.6 1.0 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 GREB1 PF15782.5 CDJ53610.1 - 2.5 5.1 13.1 2.8 4.9 13.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CDJ53610.1 - 3.4 7.6 18.8 4.1 7.3 18.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med24_N PF11277.8 CDJ53610.1 - 3.5 5.6 8.2 3.6 5.5 8.2 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal AP-5_subunit_s1 PF15001.6 CDJ53610.1 - 3.8 7.5 8.0 4.3 7.3 8.0 1.0 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF1635 PF07795.11 CDJ53610.1 - 4.7 7.0 12.2 6.4 6.6 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) CLN3 PF02487.17 CDJ53610.1 - 4.7 6.1 5.2 4.9 6.1 5.2 1.0 1 0 0 1 1 1 0 CLN3 protein Lin-8 PF03353.15 CDJ53610.1 - 4.7 6.7 12.1 5.8 6.4 12.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist V_ATPase_I PF01496.19 CDJ53610.1 - 5.7 4.7 7.4 5.9 4.7 7.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Leu_zip PF15294.6 CDJ53611.1 - 0.00078 19.0 4.9 0.00078 19.0 4.9 2.3 2 1 0 2 2 2 1 Leucine zipper Spt20 PF12090.8 CDJ53611.1 - 0.0043 16.7 17.7 0.0043 16.7 17.7 3.3 2 1 1 3 3 3 1 Spt20 family Activator_LAG-3 PF11498.8 CDJ53611.1 - 0.0076 15.3 18.4 0.0076 15.3 18.4 2.2 2 0 0 2 2 2 1 Transcriptional activator LAG-3 ATG2_CAD PF13329.6 CDJ53611.1 - 0.13 11.9 0.1 0.13 11.9 0.1 2.4 2 0 0 2 2 2 0 Autophagy-related protein 2 CAD motif Paf1 PF03985.13 CDJ53611.1 - 0.23 10.4 28.6 0.23 10.4 16.7 2.2 2 0 0 2 2 2 0 Paf1 MecA PF05389.12 CDJ53611.1 - 1.3 8.6 17.8 1.2 8.7 2.3 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Neur_chan_memb PF02932.16 CDJ53611.1 - 4.9 7.1 21.8 4.3 7.3 2.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 CDJ53611.1 - 7 6.6 18.0 6.4 6.7 1.0 2.2 2 0 0 2 2 2 0 Protein Family FAM60A TFIIA PF03153.13 CDJ53612.1 - 1.8e-05 25.0 5.2 1.8e-05 25.0 5.2 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit HEAT_EZ PF13513.6 CDJ53612.1 - 9e-05 22.9 0.7 9e-05 22.9 0.7 6.2 3 3 6 9 9 9 2 HEAT-like repeat DUF3385 PF11865.8 CDJ53612.1 - 0.00079 19.4 5.4 0.13 12.2 0.4 3.6 3 2 1 5 5 5 2 Domain of unknown function (DUF3385) SPX PF03105.19 CDJ53612.1 - 0.0087 16.0 11.4 0.013 15.5 11.4 1.1 1 0 0 1 1 1 1 SPX domain BP28CT PF08146.12 CDJ53612.1 - 0.014 15.2 0.8 1.9 8.3 0.1 2.8 3 0 0 3 3 3 0 BP28CT (NUC211) domain DUF572 PF04502.13 CDJ53612.1 - 2.4 7.7 6.8 4.8 6.7 6.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) FGF-BP1 PF06473.12 CDJ53612.1 - 2.4 7.9 9.8 0.94 9.3 1.0 2.3 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) PAP1 PF08601.10 CDJ53612.1 - 3.3 7.3 23.5 5.4 6.6 23.5 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 NST1 PF13945.6 CDJ53612.1 - 8.6 6.4 14.6 32 4.6 14.6 1.8 1 1 0 1 1 1 0 Salt tolerance down-regulator E_Pc_C PF06752.12 CDJ53612.1 - 9.7 6.2 38.6 0.29 11.2 23.6 2.5 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Prefoldin_2 PF01920.20 CDJ53613.1 - 1.3e-13 50.8 0.1 9.8e-10 38.3 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit BicD PF09730.9 CDJ53613.1 - 0.0087 14.5 0.6 0.012 14.1 0.6 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D TMF_DNA_bd PF12329.8 CDJ53613.1 - 0.026 14.5 0.5 0.041 13.9 0.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 CDJ53613.1 - 0.31 10.9 1.4 0.54 10.1 1.4 1.3 1 0 0 1 1 1 0 Septum formation initiator FAM60A PF15396.6 CDJ53614.1 - 0.022 14.8 26.1 0.026 14.6 26.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 CDJ53614.1 - 0.11 11.2 41.1 0.13 11.0 41.1 1.0 1 0 0 1 1 1 0 Presenilin CCSAP PF15748.5 CDJ53614.1 - 0.12 12.6 37.6 0.14 12.3 37.6 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 CDJ53614.1 - 0.23 9.7 30.1 0.25 9.6 30.1 1.0 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ53614.1 - 0.36 9.8 38.1 0.43 9.5 38.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF572 PF04502.13 CDJ53614.1 - 0.37 10.4 29.3 0.42 10.2 29.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4045 PF13254.6 CDJ53614.1 - 0.44 10.1 28.7 0.46 10.1 28.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF5427 PF10310.9 CDJ53614.1 - 0.58 9.0 32.7 0.73 8.7 32.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) RR_TM4-6 PF06459.12 CDJ53614.1 - 1.2 8.9 37.0 1.4 8.7 37.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1387 PF07139.11 CDJ53614.1 - 1.3 8.7 31.8 1.6 8.4 31.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF3807 PF12720.7 CDJ53614.1 - 1.4 9.2 43.8 2.2 8.5 43.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Lin-8 PF03353.15 CDJ53614.1 - 2.4 7.6 39.2 2.7 7.4 39.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PA26 PF04636.13 CDJ53614.1 - 2.6 6.9 27.9 3 6.7 27.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PAT1 PF09770.9 CDJ53614.1 - 2.9 6.0 57.8 3.3 5.9 57.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Endostatin PF06482.11 CDJ53614.1 - 3 7.2 31.4 4.3 6.7 31.4 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Hid1 PF12722.7 CDJ53614.1 - 3.2 5.8 33.9 3.7 5.6 33.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MAJIN PF15077.6 CDJ53614.1 - 3.5 7.4 25.4 4.2 7.1 25.4 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein AAA_11 PF13086.6 CDJ53614.1 - 3.6 7.3 33.5 4.2 7.1 33.5 1.1 1 0 0 1 1 1 0 AAA domain DUF4569 PF15133.6 CDJ53614.1 - 4.1 7.1 35.7 5 6.7 35.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Membralin PF09746.9 CDJ53614.1 - 5.1 6.0 23.0 6.1 5.8 23.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein MDM10 PF12519.8 CDJ53614.1 - 6.8 5.4 31.5 7.6 5.3 31.5 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF2052 PF09747.9 CDJ53614.1 - 7.8 6.6 36.8 10 6.2 36.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) MCM_bind PF09739.9 CDJ53614.1 - 7.9 4.8 31.4 9.4 4.5 31.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor GREB1 PF15782.5 CDJ53614.1 - 8 3.4 36.0 8.8 3.3 36.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PIP5K PF01504.18 CDJ53615.1 - 0.00012 21.4 0.4 0.00012 21.4 0.4 9.5 6 3 1 7 7 7 1 Phosphatidylinositol-4-phosphate 5-Kinase SR-25 PF10500.9 CDJ53615.1 - 0.0036 16.9 24.7 0.0036 16.9 24.7 12.9 7 5 4 11 11 11 3 Nuclear RNA-splicing-associated protein Ribosomal_S3_C PF00189.20 CDJ53616.1 - 2.5e-11 43.9 0.3 2.5e-11 43.9 0.3 2.8 3 0 0 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CDJ53616.1 - 6.4e-10 38.7 0.0 6.4e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 KH domain RskA PF10099.9 CDJ53616.1 - 2.6e-06 27.9 3.1 2.6e-06 27.9 3.1 9.3 4 3 3 7 7 7 2 Anti-sigma-K factor rskA RskA PF10099.9 CDJ53617.1 - 0.0078 16.5 1.4 0.0078 16.5 1.4 9.6 2 2 3 6 6 6 2 Anti-sigma-K factor rskA Pex14_N PF04695.13 CDJ53618.1 - 0.099 13.3 24.3 0.14 12.8 24.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dsh_C PF12316.8 CDJ53618.1 - 0.21 12.0 21.3 0.23 11.9 21.3 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal BAF1_ABF1 PF04684.13 CDJ53618.1 - 0.4 9.7 21.5 0.49 9.4 21.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor VIT1 PF01988.19 CDJ53618.1 - 0.53 10.1 10.2 0.58 10.0 10.2 1.1 1 0 0 1 1 1 0 VIT family NicO PF03824.16 CDJ53618.1 - 0.98 8.7 22.1 1.2 8.4 22.1 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Zip PF02535.22 CDJ53618.1 - 1.3 8.2 25.6 1.5 8.0 25.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter STAC2_u1 PF16664.5 CDJ53618.1 - 1.4 9.3 15.0 1.8 9.1 15.0 1.2 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Auxin_canalis PF05703.11 CDJ53618.1 - 1.8 8.4 21.2 2.2 8.2 21.2 1.1 1 0 0 1 1 1 0 Auxin canalisation Mitofilin PF09731.9 CDJ53618.1 - 2.2 7.0 26.1 2.6 6.8 26.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2076 PF09849.9 CDJ53618.1 - 3.2 7.7 31.5 4.1 7.4 31.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF5427 PF10310.9 CDJ53618.1 - 3.7 6.4 24.2 4.4 6.2 24.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) RIFIN PF02009.16 CDJ53618.1 - 4.9 7.0 12.4 5.8 6.7 12.4 1.1 1 0 0 1 1 1 0 Rifin MCU PF04678.13 CDJ53618.1 - 5 7.2 12.3 5.9 7.0 12.3 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Endostatin PF06482.11 CDJ53618.1 - 5.1 6.5 23.7 5.9 6.3 23.7 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4366 PF14283.6 CDJ53618.1 - 5.6 7.0 7.6 8 6.5 7.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) XRCC4 PF06632.12 CDJ53618.1 - 7.5 5.3 15.6 9.4 5.0 15.6 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Spc7_N PF15402.6 CDJ53618.1 - 7.9 4.6 18.8 9 4.4 18.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Ribosomal_60s PF00428.19 CDJ53618.1 - 8.4 7.1 18.2 15 6.2 18.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein MMR1 PF08505.10 CDJ53618.1 - 8.9 6.5 24.9 11 6.2 24.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Bul1_N PF04425.12 CDJ53618.1 - 9 4.9 19.0 10 4.8 19.0 1.0 1 0 0 1 1 1 0 Bul1 N terminus MMM1 PF10296.9 CDJ53619.1 - 0.14 11.2 12.6 0.19 10.7 12.6 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Velvet PF11754.8 CDJ53619.1 - 0.18 11.7 17.4 0.22 11.5 17.4 1.1 1 0 0 1 1 1 0 Velvet factor AAA_11 PF13086.6 CDJ53619.1 - 0.25 11.1 18.4 0.28 10.9 18.4 1.0 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 CDJ53619.1 - 0.28 11.0 17.5 0.32 10.8 17.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ53619.1 - 0.31 9.8 21.3 0.33 9.7 21.3 1.1 1 0 0 1 1 1 0 Presenilin DUF3295 PF11702.8 CDJ53619.1 - 0.45 9.8 17.5 0.5 9.7 17.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Paf1 PF03985.13 CDJ53619.1 - 0.66 8.9 23.7 0.77 8.7 23.7 1.0 1 0 0 1 1 1 0 Paf1 eIF-3_zeta PF05091.12 CDJ53619.1 - 0.72 8.8 24.6 0.81 8.6 24.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex14_N PF04695.13 CDJ53619.1 - 0.74 10.5 29.8 1.3 9.7 29.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.17 CDJ53619.1 - 0.97 9.5 16.4 1.1 9.4 16.4 1.1 1 0 0 1 1 1 0 DDHD domain DUF2828 PF11443.8 CDJ53619.1 - 1.1 7.3 17.2 1.1 7.3 17.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SelP_N PF04592.14 CDJ53619.1 - 1.1 8.6 23.9 1.3 8.3 23.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PAT1 PF09770.9 CDJ53619.1 - 1.2 7.3 35.0 1.3 7.2 35.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Endostatin PF06482.11 CDJ53619.1 - 1.4 8.3 19.9 1.4 8.3 19.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin EOS1 PF12326.8 CDJ53619.1 - 1.4 8.8 9.2 1.7 8.5 9.2 1.3 1 0 0 1 1 1 0 N-glycosylation protein Serinc PF03348.15 CDJ53619.1 - 1.6 7.5 10.9 1.7 7.5 10.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TCP PF03634.13 CDJ53619.1 - 1.8 9.1 19.8 2.6 8.6 19.8 1.2 1 0 0 1 1 1 0 TCP family transcription factor DUF4820 PF16091.5 CDJ53619.1 - 1.9 7.8 14.9 2.5 7.4 14.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Connexin PF00029.19 CDJ53619.1 - 2.7 7.7 16.5 3 7.5 16.5 1.2 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 CDJ53619.1 - 3 7.9 16.4 3.3 7.7 16.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 CDJ53619.1 - 4 6.3 20.8 4.5 6.2 20.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CobT PF06213.12 CDJ53619.1 - 4.9 6.4 24.9 6.3 6.1 24.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM60A PF15396.6 CDJ53619.1 - 5.6 6.9 17.0 6.2 6.8 17.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CLN3 PF02487.17 CDJ53619.1 - 5.8 5.8 16.0 6.6 5.7 16.0 1.2 1 0 0 1 1 1 0 CLN3 protein SID-1_RNA_chan PF13965.6 CDJ53619.1 - 6.2 5.1 9.3 5.8 5.2 9.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Asparaginase_2 PF01112.18 CDJ53619.1 - 6.7 5.6 12.9 9.2 5.2 12.9 1.2 1 0 0 1 1 1 0 Asparaginase CDK5_activator PF03261.15 CDJ53619.1 - 7.4 6.0 20.5 9.1 5.7 20.5 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Membralin PF09746.9 CDJ53619.1 - 7.7 5.4 13.5 7.7 5.4 13.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF3276 PF11680.8 CDJ53619.1 - 8.2 6.6 18.1 12 6.1 18.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) DUF4175 PF13779.6 CDJ53619.1 - 9.1 4.0 44.6 10 3.9 44.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Virul_Fac PF10139.9 CDJ53620.1 - 1.1 7.4 6.8 1.3 7.1 6.8 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor CAP_N PF01213.19 CDJ53620.1 - 1.7 8.1 9.6 1.9 7.9 9.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FSA_C PF10479.9 CDJ53620.1 - 6.5 4.7 5.6 7 4.6 5.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Epimerase PF01370.21 CDJ53621.1 - 7.1e-43 146.8 0.0 1e-42 146.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ53621.1 - 5.4e-06 26.0 0.0 7.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDJ53621.1 - 0.00013 21.0 0.0 0.00035 19.7 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDJ53621.1 - 0.00053 19.2 0.0 0.00087 18.5 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CDJ53621.1 - 0.01 15.0 0.1 0.019 14.1 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CDJ53621.1 - 0.29 10.2 1.2 0.29 10.2 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein DUF632 PF04782.12 CDJ53622.1 - 0.001 18.4 1.2 0.001 18.4 1.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF632) GHL5 PF14872.6 CDJ53622.1 - 0.025 12.6 1.3 0.038 12.0 1.3 1.1 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 LMBR1 PF04791.16 CDJ53622.1 - 1.4 7.7 9.5 0.083 11.8 2.6 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein UPF0242 PF06785.11 CDJ53622.1 - 3.2 7.8 15.8 0.43 10.7 6.5 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus BRCT_3 PF18428.1 CDJ53623.1 - 0.0017 18.4 0.0 5.7 7.1 0.0 3.3 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 CDJ53623.1 - 0.0065 16.8 1.9 0.044 14.2 0.0 3.1 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CDJ53623.1 - 0.069 13.6 0.0 30 5.1 0.0 3.6 4 0 0 4 4 4 0 BRCT domain, a BRCA1 C-terminus domain ABC2_membrane_2 PF12679.7 CDJ53624.1 - 0.047 13.0 0.9 0.067 12.5 0.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Presenilin PF01080.17 CDJ53624.1 - 0.069 11.9 31.7 0.076 11.8 31.7 1.1 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 CDJ53624.1 - 0.17 10.7 19.1 0.17 10.7 19.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FAM60A PF15396.6 CDJ53624.1 - 0.44 10.5 21.1 0.64 10.0 21.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4045 PF13254.6 CDJ53624.1 - 0.45 10.1 20.8 0.52 9.9 20.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.9 CDJ53624.1 - 0.65 8.2 45.9 0.68 8.1 45.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ53624.1 - 0.71 9.0 24.5 0.85 8.8 24.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter LAP1C PF05609.12 CDJ53624.1 - 0.77 8.8 23.3 0.74 8.8 23.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Plasmodium_Vir PF05795.11 CDJ53624.1 - 1.5 8.2 11.1 1.5 8.1 11.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 CDJ53624.1 - 2.5 7.9 23.5 2.9 7.7 23.5 1.1 1 0 0 1 1 1 0 SPX domain Dicty_REP PF05086.12 CDJ53624.1 - 3.5 5.5 16.6 4.1 5.2 16.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2052 PF09747.9 CDJ53624.1 - 4.3 7.4 30.8 5.1 7.2 30.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SLC12 PF03522.15 CDJ53624.1 - 4.3 6.2 29.5 5 6.0 29.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CDJ53624.1 - 6.2 3.8 33.1 6.4 3.7 33.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1387 PF07139.11 CDJ53624.1 - 6.5 6.4 25.9 8.9 5.9 25.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) RR_TM4-6 PF06459.12 CDJ53625.1 - 1.4 8.7 13.6 3 7.6 13.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_60s PF00428.19 CDJ53625.1 - 1.5 9.5 10.0 3.1 8.4 10.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein SelP_N PF04592.14 CDJ53625.1 - 10 5.5 29.1 0.093 12.1 18.9 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region IMUP PF15761.5 CDJ53626.1 - 0.018 15.7 1.5 0.026 15.2 1.5 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ53626.1 - 0.039 13.6 6.0 0.046 13.3 6.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CDJ53626.1 - 0.076 13.6 2.3 0.11 13.0 2.3 1.4 1 0 0 1 1 1 0 Dehydrin Spt20 PF12090.8 CDJ53626.1 - 0.26 10.8 10.5 0.35 10.5 10.5 1.1 1 0 0 1 1 1 0 Spt20 family SDP_N PF12278.8 CDJ53626.1 - 0.4 10.8 3.4 0.6 10.2 3.4 1.2 1 0 0 1 1 1 0 Sex determination protein N terminal SR-25 PF10500.9 CDJ53627.1 - 0.037 13.6 44.3 0.22 11.1 44.3 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 CDJ53627.1 - 0.083 13.7 7.8 0.14 13.0 7.8 1.4 1 0 0 1 1 1 0 Chorion family 2 Grg1 PF11034.8 CDJ53627.1 - 0.28 11.4 30.7 1.6 9.0 2.3 3.6 1 1 1 2 2 2 0 Glucose-repressible protein Grg1 CCSAP PF15748.5 CDJ53627.1 - 0.38 10.9 34.5 0.46 10.6 34.5 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF3446 PF11928.8 CDJ53627.1 - 0.59 10.5 17.0 0.85 10.0 17.0 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain Trypan_PARP PF05887.11 CDJ53627.1 - 3.9 7.4 29.5 22 5.1 29.5 1.9 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4769 PF15992.5 CDJ53627.1 - 7.3 6.3 15.8 8.9 6.0 15.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) SUIM_assoc PF16619.5 CDJ53628.1 - 0.034 14.2 1.4 0.034 14.2 1.4 4.1 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Filament_head PF04732.14 CDJ53628.1 - 0.28 12.1 28.5 0.33 11.8 3.1 3.5 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region Ribosomal_60s PF00428.19 CDJ53628.1 - 2.4 8.8 63.9 0.32 11.6 14.8 4.6 4 0 0 4 4 4 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ53628.1 - 4.3 6.9 28.9 0.43 10.1 3.5 2.5 3 0 0 3 3 3 0 Spt20 family RR_TM4-6 PF06459.12 CDJ53628.1 - 7.8 6.2 9.6 16 5.2 2.8 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2484 PF10658.9 CDJ53632.1 - 0.14 12.4 1.7 0.28 11.5 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) WD40 PF00400.32 CDJ53633.1 - 0.078 13.9 0.0 1.4 10.0 0.1 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat HEAT PF02985.22 CDJ53634.1 - 0.34 11.3 3.0 79 3.9 0.0 5.0 3 0 0 3 3 3 0 HEAT repeat zf-CCCH_2 PF14608.6 CDJ53635.1 - 2.2e-09 37.5 32.0 0.00021 21.6 5.1 3.3 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CDJ53635.1 - 5.3e-06 26.1 17.2 0.084 12.7 0.1 4.2 4 0 0 4 4 4 3 CCCH-type zinc finger Nab2p_Zf1 PF18260.1 CDJ53635.1 - 0.0062 16.4 12.0 0.035 14.0 3.0 2.8 2 0 0 2 2 2 2 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 zf_CCCH_4 PF18345.1 CDJ53635.1 - 0.0087 16.1 21.5 0.19 11.8 0.8 4.2 3 1 1 4 4 4 3 Zinc finger domain zf-CCCH PF00642.24 CDJ53635.1 - 0.0088 15.9 22.1 0.013 15.4 0.7 4.0 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.17 CDJ53635.1 - 0.015 15.6 0.1 0.034 14.5 0.1 1.5 1 0 0 1 1 1 0 PWI domain DEDD_Tnp_IS110 PF01548.17 CDJ53635.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Transposase zf-CCHH PF10283.9 CDJ53635.1 - 0.53 10.3 13.7 6.9 6.8 1.1 3.9 3 0 0 3 3 3 0 PBZ domain TTL PF03133.15 CDJ53636.1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family Spt20 PF12090.8 CDJ53636.1 - 0.26 10.9 7.1 4.3 6.9 5.3 2.1 2 0 0 2 2 2 0 Spt20 family betaPIX_CC PF16523.5 CDJ53636.1 - 0.32 10.8 2.3 0.56 10.1 2.3 1.3 1 0 0 1 1 1 0 betaPIX coiled coil Glycos_transf_1 PF00534.20 CDJ53637.1 - 7.8e-31 106.9 0.0 2e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ53637.1 - 1.6e-24 86.9 0.0 3.7e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CDJ53637.1 - 1.3e-18 67.5 1.5 2.5e-10 40.6 0.0 3.3 2 1 1 3 3 3 2 Glycosyltransferase Family 4 Alpha-amylase_C PF02806.18 CDJ53637.1 - 1.6e-14 54.1 0.0 4.5e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Glyco_trans_4_4 PF13579.6 CDJ53637.1 - 2.2e-09 38.0 10.4 0.00036 21.0 0.1 5.0 4 1 1 5 5 5 2 Glycosyl transferase 4-like domain Alpha-amylase PF00128.24 CDJ53637.1 - 2.3e-08 34.0 0.1 4.3e-05 23.2 0.0 2.3 1 1 0 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 CDJ53637.1 - 1.6e-07 31.5 0.0 1.7e-06 28.3 0.0 2.3 1 1 1 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_transf_5 PF08323.11 CDJ53637.1 - 2.7e-07 30.6 0.1 0.00012 21.9 0.2 2.5 1 1 1 2 2 2 2 Starch synthase catalytic domain Optomotor-blind PF11078.8 CDJ53638.1 - 0.021 15.4 2.0 0.069 13.7 0.8 2.1 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region PP2C_2 PF13672.6 CDJ53639.1 - 0.048 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C Gpi1 PF05024.15 CDJ53640.1 - 4.7e-24 85.5 1.0 3e-12 47.0 0.1 2.5 2 0 0 2 2 2 2 N-acetylglucosaminyl transferase component (Gpi1) SPX PF03105.19 CDJ53640.1 - 0.44 10.4 0.0 0.44 10.4 0.0 4.7 3 2 1 4 4 4 0 SPX domain DUF5542 PF17696.1 CDJ53640.1 - 0.46 10.6 0.0 0.41 10.8 3.0 5.5 6 0 0 6 6 6 0 Family of unknown function (DUF5542) C2 PF00168.30 CDJ53642.1 - 2.8e-07 30.8 0.0 6.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain SR-25 PF10500.9 CDJ53642.1 - 6e-05 22.8 7.7 6e-05 22.8 7.7 3.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.10 CDJ53642.1 - 0.00018 21.6 11.6 0.02 15.0 2.5 2.5 2 0 0 2 2 2 2 Peptidase family S49 N-terminal Presenilin PF01080.17 CDJ53642.1 - 0.00027 19.8 14.6 0.0026 16.6 4.5 2.4 2 0 0 2 2 2 2 Presenilin PIP5K PF01504.18 CDJ53642.1 - 0.00028 20.2 11.0 0.0028 16.9 0.3 2.4 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase SARAF PF06682.12 CDJ53642.1 - 0.00087 19.0 16.4 0.0057 16.3 8.3 2.5 2 0 0 2 2 2 2 SOCE-associated regulatory factor of calcium homoeostasis SLC12 PF03522.15 CDJ53642.1 - 0.0086 15.1 11.3 0.01 14.9 0.8 2.2 2 0 0 2 2 2 1 Solute carrier family 12 TRAP_alpha PF03896.16 CDJ53642.1 - 0.023 13.9 10.7 0.033 13.4 3.7 2.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Amnionless PF14828.6 CDJ53642.1 - 0.042 12.7 9.2 0.053 12.3 1.5 2.4 2 0 0 2 2 2 0 Amnionless FAM176 PF14851.6 CDJ53642.1 - 0.068 12.8 12.3 0.14 11.8 2.5 2.7 2 0 0 2 2 2 0 FAM176 family MecA PF05389.12 CDJ53642.1 - 0.086 12.5 11.9 0.11 12.2 2.2 2.4 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Serinc PF03348.15 CDJ53642.1 - 0.096 11.6 13.8 0.63 8.9 6.4 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) AAA_23 PF13476.6 CDJ53642.1 - 0.12 12.8 28.1 0.42 11.1 9.1 2.3 2 0 0 2 2 2 0 AAA domain Connexin PF00029.19 CDJ53642.1 - 0.16 11.7 12.5 2.1 8.1 0.9 2.3 2 0 0 2 2 2 0 Connexin SpoIIP PF07454.11 CDJ53642.1 - 0.19 11.2 16.0 0.21 11.0 3.7 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Scs3p PF10261.9 CDJ53642.1 - 0.19 11.2 8.2 0.053 13.0 1.1 2.2 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF572 PF04502.13 CDJ53642.1 - 0.19 11.3 16.2 0.38 10.3 6.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) SID-1_RNA_chan PF13965.6 CDJ53642.1 - 0.24 9.8 5.5 0.47 8.8 1.9 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Suf PF05843.14 CDJ53642.1 - 0.4 10.6 25.1 0.75 9.7 7.1 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) CLN3 PF02487.17 CDJ53642.1 - 0.66 9.0 11.2 1 8.3 3.7 2.2 2 0 0 2 2 2 0 CLN3 protein DUF1980 PF09323.10 CDJ53642.1 - 0.66 9.9 12.7 0.33 10.9 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PAT1 PF09770.9 CDJ53642.1 - 0.68 8.1 33.0 0.34 9.1 10.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.19 CDJ53642.1 - 0.75 7.6 20.1 0.052 11.5 5.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CSG2 PF16965.5 CDJ53642.1 - 0.96 8.3 10.0 4.1 6.2 4.5 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator Caldesmon PF02029.15 CDJ53642.1 - 1.9 7.2 26.1 0.022 13.6 6.0 2.3 2 0 0 2 2 2 0 Caldesmon SART-1 PF03343.13 CDJ53642.1 - 2.1 6.8 24.8 1.5 7.3 10.5 2.2 2 0 0 2 2 2 0 SART-1 family DUF2052 PF09747.9 CDJ53642.1 - 2.7 8.1 27.8 2.4 8.2 10.4 2.7 3 0 0 3 3 2 0 Coiled-coil domain containing protein (DUF2052) PA26 PF04636.13 CDJ53642.1 - 3 6.7 14.9 1 8.2 5.1 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) DUF2828 PF11443.8 CDJ53642.1 - 3 5.8 18.2 1.5 6.8 7.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Eapp_C PF10238.9 CDJ53642.1 - 4.3 7.4 18.9 4.5 7.3 5.9 2.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein MMM1 PF10296.9 CDJ53642.1 - 4.8 6.1 9.8 0.55 9.2 0.8 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 CNDH2_C PF16858.5 CDJ53642.1 - 5.2 6.9 22.0 4.8 7.0 8.1 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CCSAP PF15748.5 CDJ53642.1 - 5.7 7.0 36.2 0.088 13.0 11.0 3.1 3 1 0 3 3 3 0 Centriole, cilia and spindle-associated DUF4776 PF16003.5 CDJ53642.1 - 6 5.7 14.1 4.7 6.1 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) CAF1 PF04857.20 CDJ53642.1 - 7.7 5.6 9.6 14 4.7 0.3 2.2 2 0 0 2 2 2 0 CAF1 family ribonuclease PEPCK_ATP PF01293.20 CDJ53643.1 - 7 5.2 10.3 9.9 4.7 10.3 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase SPX PF03105.19 CDJ53644.1 - 0.04 13.8 6.4 0.055 13.4 6.4 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ53644.1 - 1.8 7.3 5.7 2.2 7.1 5.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF515 PF04415.12 CDJ53644.1 - 2.2 6.6 11.9 2.5 6.4 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RAP1 PF07218.11 CDJ53644.1 - 5.1 5.2 18.7 6.7 4.8 18.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Bclt PF15318.6 CDJ53644.1 - 9 6.1 7.4 6.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis RskA PF10099.9 CDJ53645.1 - 0.033 14.5 17.1 0.042 14.1 17.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA GED PF02212.18 CDJ53645.1 - 1.2 9.4 6.0 1.9 8.7 6.0 1.2 1 0 0 1 1 1 0 Dynamin GTPase effector domain IHABP4_N PF16174.5 CDJ53645.1 - 2.1 8.9 5.6 2.9 8.5 5.6 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal AP2 PF00847.20 CDJ53647.1 - 1.1e-09 38.4 2.0 1.1e-09 38.4 2.0 3.3 4 0 0 4 4 4 1 AP2 domain Neur_chan_memb PF02932.16 CDJ53647.1 - 0.29 11.2 6.0 0.12 12.4 3.6 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 CDJ53647.1 - 0.61 10.2 12.0 1.1 9.4 12.0 1.4 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ53647.1 - 0.75 8.7 16.6 0.95 8.4 16.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIEZO PF15917.5 CDJ53647.1 - 2.1 7.8 24.3 4.2 6.8 24.3 1.4 1 0 0 1 1 1 0 Piezo LIM_bind PF01803.16 CDJ53647.1 - 3.7 7.0 14.9 6.5 6.2 14.9 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Suf PF05843.14 CDJ53647.1 - 6.4 6.7 17.1 0.7 9.8 12.2 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Peptidase_S49_N PF08496.10 CDJ53648.1 - 0.009 16.1 6.6 0.009 16.1 6.6 3.9 4 0 0 4 4 4 1 Peptidase family S49 N-terminal DUF2828 PF11443.8 CDJ53648.1 - 0.29 9.2 8.3 1.4 6.9 8.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) ALMT PF11744.8 CDJ53648.1 - 3.5 6.3 4.8 8.7 5.1 4.8 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter PNISR PF15996.5 CDJ53650.1 - 3.5 7.9 28.7 0.033 14.5 9.7 3.1 3 0 0 3 3 3 0 Arginine/serine-rich protein PNISR KH_1 PF00013.29 CDJ53651.1 - 6.4e-07 29.1 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 KH domain Fer2_4 PF13510.6 CDJ53651.1 - 0.078 13.0 0.4 0.078 13.0 0.4 2.9 4 0 0 4 4 4 0 2Fe-2S iron-sulfur cluster binding domain Spt20 PF12090.8 CDJ53651.1 - 6.6 6.3 16.2 0.29 10.7 9.3 2.1 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ53652.1 - 0.00012 21.2 17.9 0.00012 21.2 17.9 5.7 5 0 0 5 5 5 2 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ53652.1 - 0.00098 19.5 16.7 0.00098 19.5 16.7 9.4 5 2 2 7 7 7 4 Anti-sigma-K factor rskA Peptidase_S64 PF08192.11 CDJ53653.1 - 0.00099 17.7 11.3 0.0013 17.3 11.3 1.1 1 0 0 1 1 1 1 Peptidase family S64 DUF3464 PF11947.8 CDJ53653.1 - 0.0041 16.9 5.2 0.0041 16.9 5.2 2.1 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 Apt1 PF10351.9 CDJ53653.1 - 0.0073 15.2 8.0 0.0092 14.9 8.0 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ53653.1 - 0.018 14.6 11.9 0.018 14.6 11.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Plasmodium_Vir PF05795.11 CDJ53653.1 - 0.082 12.3 6.1 0.11 11.9 6.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF5308 PF17233.2 CDJ53653.1 - 0.25 11.6 16.5 0.35 11.1 9.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Pap_E4 PF02711.14 CDJ53653.1 - 1.1 10.3 16.0 4.8 8.2 2.6 2.3 2 0 0 2 2 2 0 E4 protein TERB2 PF15101.6 CDJ53653.1 - 1.5 8.9 21.7 0.89 9.6 14.0 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 CNDH2_M PF16869.5 CDJ53653.1 - 1.6 9.5 14.8 0.61 10.8 5.2 2.2 2 0 0 2 2 2 0 PF16858 Rtf2 PF04641.12 CDJ53653.1 - 1.8 7.9 15.6 1.5 8.1 5.4 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger FAM176 PF14851.6 CDJ53653.1 - 2.5 7.7 12.0 1.1 9.0 5.3 2.1 2 0 0 2 2 2 0 FAM176 family DUF4667 PF15700.5 CDJ53653.1 - 2.9 7.9 19.5 0.042 14.0 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Tim54 PF11711.8 CDJ53653.1 - 4.6 5.9 15.3 0.25 10.1 7.5 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CTU2 PF10288.9 CDJ53653.1 - 5 7.4 15.1 1.1 9.5 7.0 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 SRP-alpha_N PF04086.13 CDJ53653.1 - 6.1 6.7 23.8 9.6 6.0 23.8 1.2 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Totivirus_coat PF05518.11 CDJ53653.1 - 6.7 4.6 10.7 9.2 4.2 10.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein DUF3408 PF11888.8 CDJ53653.1 - 7.3 6.7 23.1 3 8.0 16.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) zf-CW PF07496.15 CDJ53654.1 - 2.7e-15 56.1 4.6 2.7e-15 56.1 4.6 2.0 2 0 0 2 2 2 1 CW-type Zinc Finger ANAPC4_WD40 PF12894.7 CDJ53654.1 - 0.00013 22.2 0.1 0.075 13.3 0.0 3.2 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ53654.1 - 0.0053 17.6 4.2 8.3 7.5 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat SUIM_assoc PF16619.5 CDJ53654.1 - 0.0083 16.2 1.3 0.0083 16.2 1.3 27.2 20 9 3 23 23 23 2 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ53655.1 - 0.0041 16.8 15.5 0.0041 16.8 15.5 3.2 1 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein FAM83 PF07894.12 CDJ53655.1 - 0.45 10.0 6.5 0.68 9.4 6.5 1.2 1 0 0 1 1 1 0 FAM83 A-H Tim54 PF11711.8 CDJ53655.1 - 2 7.1 11.9 3.1 6.5 11.9 1.4 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3391 PF11871.8 CDJ53655.1 - 4.6 7.8 14.1 0.55 10.8 5.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Roughex PF06020.11 CDJ53655.1 - 4.6 6.2 13.0 0.34 10.0 7.8 1.9 2 0 0 2 2 2 0 Drosophila roughex protein AP2 PF00847.20 CDJ53656.1 - 3.7e-10 39.9 3.4 3.7e-10 39.9 3.4 6.5 8 0 0 8 8 8 1 AP2 domain RskA PF10099.9 CDJ53657.1 - 0.1 12.9 46.1 0.2 11.9 8.7 2.3 1 1 0 2 2 2 0 Anti-sigma-K factor rskA MARVEL PF01284.23 CDJ53657.1 - 0.11 12.6 3.0 0.51 10.4 0.3 2.4 2 0 0 2 2 2 0 Membrane-associating domain Dehydrin PF00257.19 CDJ53657.1 - 5.4 7.5 16.5 12 6.4 10.5 2.3 2 0 0 2 2 2 0 Dehydrin DivIC PF04977.15 CDJ53658.1 - 3.5 7.5 6.4 0.22 11.3 0.9 1.8 2 0 0 2 2 2 0 Septum formation initiator DUF3381 PF11861.8 CDJ53659.1 - 0.008 16.0 1.7 0.01 15.7 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) Methyltransf_34 PF11312.8 CDJ53659.1 - 0.25 10.5 0.4 0.34 10.1 0.4 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase EcsC PF12787.7 CDJ53659.1 - 1 9.0 6.4 2.2 7.9 0.4 2.1 2 0 0 2 2 2 0 EcsC protein family Gag_p17 PF00540.18 CDJ53659.1 - 2.8 7.9 5.6 0.97 9.4 0.3 2.1 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) SR-25 PF10500.9 CDJ53662.1 - 0.0029 17.2 7.0 0.0029 17.2 7.0 4.4 2 1 2 5 5 5 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ53663.1 - 0.015 15.6 15.1 0.022 15.1 15.1 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA AAA_23 PF13476.6 CDJ53663.1 - 0.07 13.6 13.4 0.067 13.7 13.4 1.1 1 0 0 1 1 1 0 AAA domain Connexin PF00029.19 CDJ53663.1 - 0.094 12.5 7.4 0.085 12.6 7.4 1.1 1 0 0 1 1 1 0 Connexin FHIPEP PF00771.20 CDJ53663.1 - 0.3 9.5 6.4 0.28 9.6 6.4 1.1 1 0 0 1 1 1 0 FHIPEP family DUF1980 PF09323.10 CDJ53663.1 - 0.38 10.7 8.8 0.36 10.7 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) THOC2_N PF16134.5 CDJ53663.1 - 0.74 8.4 10.5 0.85 8.2 10.5 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus EOS1 PF12326.8 CDJ53663.1 - 0.79 9.6 5.5 0.79 9.6 5.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein SID-1_RNA_chan PF13965.6 CDJ53663.1 - 0.8 8.0 3.5 0.73 8.2 3.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDHD PF02862.17 CDJ53663.1 - 1 9.5 11.9 1 9.5 11.9 1.1 1 0 0 1 1 1 0 DDHD domain TFB6 PF17110.5 CDJ53663.1 - 1 9.1 7.1 0.98 9.1 7.1 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Activator_LAG-3 PF11498.8 CDJ53663.1 - 1.2 8.0 40.5 1.2 8.0 40.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 V_ATPase_I PF01496.19 CDJ53663.1 - 1.2 6.9 12.2 1.1 7.1 12.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec62 PF03839.16 CDJ53663.1 - 1.3 8.5 8.9 1.2 8.6 8.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 eIF-3_zeta PF05091.12 CDJ53663.1 - 1.4 7.8 19.2 1.4 7.8 19.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 CDJ53663.1 - 1.4 8.3 15.0 1.4 8.3 15.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Peptidase_S15 PF02129.18 CDJ53663.1 - 1.6 8.3 11.8 1.7 8.2 11.8 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Band_3_cyto PF07565.13 CDJ53663.1 - 1.9 8.2 11.0 1.8 8.3 11.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Serinc PF03348.15 CDJ53663.1 - 2 7.2 7.9 2.1 7.2 7.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) CSG2 PF16965.5 CDJ53663.1 - 2.1 7.2 6.0 1.9 7.4 6.0 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator CLN3 PF02487.17 CDJ53663.1 - 2.3 7.2 8.8 2 7.4 8.8 1.1 1 0 0 1 1 1 0 CLN3 protein RR_TM4-6 PF06459.12 CDJ53663.1 - 2.7 7.7 16.2 2.8 7.7 16.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ53663.1 - 2.9 6.6 18.6 3 6.5 18.6 1.0 1 0 0 1 1 1 0 Presenilin Folate_carrier PF01770.18 CDJ53663.1 - 5.6 5.6 8.2 5.6 5.6 8.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier Neur_chan_memb PF02932.16 CDJ53663.1 - 8.1 6.4 11.7 8.2 6.4 11.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2828 PF11443.8 CDJ53663.1 - 8.9 4.3 14.0 9.7 4.1 14.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RLL PF10036.9 CDJ53665.1 - 0.00035 20.5 8.4 0.00073 19.5 8.4 1.5 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein Apt1 PF10351.9 CDJ53665.1 - 0.0082 15.0 1.7 0.012 14.5 1.7 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain FAM91_C PF14648.6 CDJ53665.1 - 0.029 13.2 0.9 0.039 12.8 0.9 1.2 1 0 0 1 1 1 0 FAM91 C-terminus Spt20 PF12090.8 CDJ53665.1 - 0.042 13.5 30.2 0.91 9.1 24.0 2.2 2 0 0 2 2 2 0 Spt20 family Plasmodium_Vir PF05795.11 CDJ53665.1 - 0.075 12.4 2.1 0.11 11.9 2.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein AIF_C PF14721.6 CDJ53665.1 - 0.14 12.5 0.7 3.8 7.9 1.8 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Rxt3 PF08642.10 CDJ53665.1 - 0.16 12.8 3.8 0.56 11.0 3.8 1.9 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Lin-8 PF03353.15 CDJ53665.1 - 0.19 11.3 9.7 0.29 10.7 9.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RICTOR_N PF14664.6 CDJ53665.1 - 0.22 10.4 3.6 0.39 9.6 3.6 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term SPX PF03105.19 CDJ53665.1 - 0.24 11.3 7.8 0.37 10.6 7.8 1.2 1 0 0 1 1 1 0 SPX domain MMR1 PF08505.10 CDJ53665.1 - 0.44 10.8 12.8 0.76 10.0 12.8 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 CDJ53665.1 - 0.53 9.0 7.4 0.97 8.1 7.4 1.4 1 0 0 1 1 1 0 Presenilin DUF4770 PF15994.5 CDJ53665.1 - 0.55 10.5 9.5 1.1 9.4 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Membr_traf_MHD PF10540.9 CDJ53665.1 - 1.6 8.9 9.7 53 4.0 9.6 2.2 1 1 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain TFIIA PF03153.13 CDJ53665.1 - 2 8.3 33.4 4.3 7.2 33.4 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ53665.1 - 2.7 6.9 8.5 3.6 6.5 8.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 CDJ53665.1 - 3.2 7.1 7.0 4.8 6.6 7.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Band_3_cyto PF07565.13 CDJ53665.1 - 7.8 6.2 14.4 16 5.2 14.4 1.6 1 1 0 1 1 1 0 Band 3 cytoplasmic domain DUF3602 PF12223.8 CDJ53666.1 - 0.036 14.6 1.4 0.069 13.8 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3602) RRM_1 PF00076.22 CDJ53669.1 - 1.5e-26 92.0 0.0 3.6e-17 61.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ53669.1 - 9.4e-06 25.7 0.1 5.6e-05 23.2 0.1 2.3 3 1 0 3 3 3 1 RNA recognition motif Pkinase PF00069.25 CDJ53670.1 - 5.8e-49 166.8 0.0 8.4e-48 163.0 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ53670.1 - 9.4e-33 113.6 0.0 2e-32 112.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ53670.1 - 2.1e-08 33.9 0.0 3.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ53670.1 - 2.5e-06 26.5 1.2 2.7e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Tubulin PF00091.25 CDJ53671.1 - 4.4e-28 98.8 1.1 3.3e-13 50.3 0.0 3.1 1 1 2 3 3 3 3 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 CDJ53671.1 - 0.022 15.1 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain AAA_6 PF12774.7 CDJ53672.1 - 4.8e-120 400.5 2.4 3.3e-119 397.7 0.1 3.0 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ53672.1 - 7.3e-82 275.6 7.1 7.3e-82 275.6 7.1 2.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CDJ53672.1 - 2.3e-59 201.1 0.0 2.3e-59 201.1 0.0 3.0 4 0 0 4 4 3 1 Dynein heavy chain C-terminal domain MT PF12777.7 CDJ53672.1 - 2.2e-56 191.4 2.8 4.6e-56 190.3 2.8 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 CDJ53672.1 - 8.3e-51 172.8 0.0 2.8e-50 171.1 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 CDJ53672.1 - 8.3e-37 126.5 0.0 2.4e-36 125.0 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ53672.1 - 3.5e-33 114.2 0.0 1.7e-31 108.8 0.0 3.4 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_9 PF12781.7 CDJ53672.1 - 1.2e-32 112.8 4.3 2.8e-32 111.6 0.0 3.6 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDJ53672.1 - 8.8e-29 100.3 0.0 1.6e-15 57.1 0.0 4.5 4 0 0 4 4 4 3 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 CDJ53672.1 - 6.8e-17 61.8 0.0 2e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDJ53672.1 - 4.5e-07 29.9 2.8 0.097 12.7 0.0 5.6 5 1 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ53672.1 - 0.00027 21.4 0.8 0.33 11.4 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ53672.1 - 0.00033 20.9 0.5 23 5.2 0.0 5.6 4 0 0 4 4 4 0 AAA domain AAA_lid_1 PF17857.1 CDJ53672.1 - 0.00063 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDJ53672.1 - 0.01 16.3 13.1 0.94 9.8 0.0 7.6 8 0 0 8 8 6 0 AAA ATPase domain MPS2 PF17060.5 CDJ53672.1 - 0.055 12.7 1.0 0.13 11.5 1.0 1.5 1 0 0 1 1 1 0 Monopolar spindle protein 2 Mg_chelatase PF01078.21 CDJ53672.1 - 0.062 12.7 1.8 11 5.3 0.1 3.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDJ53672.1 - 0.15 12.5 0.5 82 3.7 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 CDJ53672.1 - 0.26 11.0 0.1 15 5.2 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CDJ53672.1 - 0.32 10.7 7.2 8.5 6.0 0.2 3.5 3 0 0 3 3 3 0 AAA domain Kin17_mid PF10357.9 CDJ53676.1 - 1.7e-42 144.3 2.8 1.7e-42 144.3 2.8 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 CDJ53676.1 - 1.7e-21 76.1 1.9 3.1e-21 75.2 1.9 1.5 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain DUF4551 PF15087.6 CDJ53676.1 - 0.91 8.3 5.0 1.3 7.8 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pap_E4 PF02711.14 CDJ53676.1 - 1 10.3 4.9 0.17 12.8 0.8 1.8 2 0 0 2 2 2 0 E4 protein Presenilin PF01080.17 CDJ53676.1 - 3.8 6.2 5.0 4.9 5.8 5.0 1.1 1 0 0 1 1 1 0 Presenilin DUF4366 PF14283.6 CDJ53678.1 - 0.018 15.1 5.0 0.049 13.7 5.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) FAM60A PF15396.6 CDJ53678.1 - 0.27 11.2 6.1 0.35 10.8 6.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A IHABP4_N PF16174.5 CDJ53678.1 - 0.28 11.8 21.9 0.39 11.3 21.9 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal XRCC4 PF06632.12 CDJ53678.1 - 0.88 8.4 9.3 1.1 8.1 9.3 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RR_TM4-6 PF06459.12 CDJ53678.1 - 1.1 9.0 10.5 1.4 8.6 10.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4484 PF14831.6 CDJ53678.1 - 1.2 9.1 9.8 1.7 8.6 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF2391 PF09622.10 CDJ53678.1 - 1.7 7.9 7.0 1.2 8.4 1.1 2.0 2 0 0 2 2 2 0 Putative integral membrane protein (DUF2391) SLC12 PF03522.15 CDJ53678.1 - 2.7 6.9 11.1 3.1 6.7 11.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF2771 PF10969.8 CDJ53678.1 - 3.1 7.8 8.3 6.3 6.8 7.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2771) Nha1_C PF08619.10 CDJ53678.1 - 3.7 6.6 16.6 4.4 6.4 16.6 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Raftlin PF15250.6 CDJ53678.1 - 4.2 6.0 12.9 5.2 5.7 12.9 1.0 1 0 0 1 1 1 0 Raftlin FNIP_N PF14636.6 CDJ53678.1 - 4.3 8.3 14.4 5.4 8.0 14.4 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus RAB3GAP2_N PF14655.6 CDJ53678.1 - 4.5 6.4 13.6 1.5 8.0 1.2 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Zip PF02535.22 CDJ53678.1 - 7.2 5.7 8.4 8.8 5.4 8.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter WASH-7_C PF14746.6 CDJ53678.1 - 8.9 6.0 8.3 3.6 7.2 2.0 2.1 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Clat_adaptor_s PF01217.20 CDJ53679.1 - 1.4e-08 34.8 0.0 6.6e-06 26.1 0.0 2.3 2 1 0 2 2 2 2 Clathrin adaptor complex small chain RAP1 PF07218.11 CDJ53679.1 - 0.0069 14.7 14.2 0.0087 14.4 14.2 1.0 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) CytochromB561_N PF09786.9 CDJ53679.1 - 0.031 13.3 8.0 0.04 12.9 8.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.9 CDJ53679.1 - 0.059 11.9 2.0 0.057 12.0 2.0 1.1 1 0 0 1 1 1 0 Macoilin family CCDC24 PF15669.5 CDJ53679.1 - 0.19 11.6 5.4 0.29 11.0 5.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF1180 PF06679.12 CDJ53679.1 - 0.22 11.9 7.0 0.36 11.2 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Miga PF10265.9 CDJ53679.1 - 0.25 10.3 2.6 0.27 10.1 2.6 1.1 1 0 0 1 1 1 0 Mitoguardin EBP50_C PF09007.11 CDJ53679.1 - 0.51 11.3 6.1 1.1 10.3 6.1 1.5 1 1 0 1 1 1 0 EBP50, C-terminal DUF4692 PF15763.5 CDJ53679.1 - 9.6 6.6 13.9 27 5.2 13.9 1.7 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) BNIP3 PF06553.12 CDJ53680.1 - 0.33 10.6 6.9 0.33 10.6 6.4 1.2 1 1 0 1 1 1 0 BNIP3 SRP-alpha_N PF04086.13 CDJ53680.1 - 6.6 6.6 13.1 7.3 6.4 13.1 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TraT PF05818.12 CDJ53681.1 - 0.017 14.8 13.7 0.02 14.6 13.7 1.0 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Ribosomal_60s PF00428.19 CDJ53681.1 - 0.039 14.5 8.6 0.068 13.8 8.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_S49_N PF08496.10 CDJ53681.1 - 0.047 13.8 14.1 0.056 13.5 14.1 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peptidase_S15 PF02129.18 CDJ53681.1 - 0.13 11.8 11.9 0.17 11.5 11.9 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BAF1_ABF1 PF04684.13 CDJ53681.1 - 0.16 11.0 19.8 0.19 10.7 19.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Cellulose_synt PF03552.14 CDJ53681.1 - 0.42 9.0 5.8 0.46 8.9 5.8 1.0 1 0 0 1 1 1 0 Cellulose synthase R_equi_Vir PF05526.11 CDJ53681.1 - 0.43 10.4 12.2 0.62 9.9 12.2 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SID-1_RNA_chan PF13965.6 CDJ53681.1 - 0.51 8.7 8.1 0.6 8.5 8.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ53681.1 - 0.57 9.0 12.3 0.63 8.9 12.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 CDJ53681.1 - 0.59 8.8 24.2 0.67 8.7 24.2 1.0 1 0 0 1 1 1 0 Presenilin VIR_N PF15912.5 CDJ53681.1 - 0.6 9.7 9.6 0.65 9.5 9.6 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal Tim54 PF11711.8 CDJ53681.1 - 0.68 8.7 14.1 0.78 8.5 14.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2232 PF09991.9 CDJ53681.1 - 0.9 8.7 5.8 1.1 8.4 5.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) IHABP4_N PF16174.5 CDJ53681.1 - 0.93 10.1 26.8 1.3 9.6 26.8 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal CobT PF06213.12 CDJ53681.1 - 0.94 8.8 23.4 1.2 8.5 23.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SelP_N PF04592.14 CDJ53681.1 - 1 8.7 19.7 1.2 8.5 19.7 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RR_TM4-6 PF06459.12 CDJ53681.1 - 1.1 9.1 19.6 1.1 9.0 19.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.13 CDJ53681.1 - 1.1 9.9 32.6 1.7 9.3 32.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ53681.1 - 1.2 9.0 48.5 1.3 8.9 48.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ureide_permease PF07168.11 CDJ53681.1 - 1.3 7.7 8.1 1.5 7.5 8.1 1.1 1 0 0 1 1 1 0 Ureide permease ADP_ribosyl_GH PF03747.14 CDJ53681.1 - 1.3 8.6 7.1 1.6 8.4 7.1 1.0 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Ctr PF04145.15 CDJ53681.1 - 1.4 9.5 10.0 1.7 9.3 10.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF5427 PF10310.9 CDJ53681.1 - 1.5 7.7 22.8 1.8 7.5 22.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 CDJ53681.1 - 1.8 7.5 18.4 1.9 7.4 18.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Velvet PF11754.8 CDJ53681.1 - 2.4 8.0 20.2 2.6 7.9 20.2 1.0 1 0 0 1 1 1 0 Velvet factor O-antigen_lig PF13425.6 CDJ53681.1 - 2.5 6.8 7.8 2.6 6.7 7.8 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein eIF-3_zeta PF05091.12 CDJ53681.1 - 2.5 7.0 24.5 2.5 7.0 24.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hydin_ADK PF17213.3 CDJ53681.1 - 2.6 8.3 19.3 3 8.1 19.3 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain FAM60A PF15396.6 CDJ53681.1 - 2.8 7.9 15.7 3.2 7.7 15.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Endostatin PF06482.11 CDJ53681.1 - 2.8 7.3 18.2 3.2 7.1 18.2 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PMSI1 PF15322.6 CDJ53681.1 - 3.9 6.8 17.6 4.5 6.6 17.6 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF3824 PF12868.7 CDJ53681.1 - 3.9 8.1 22.9 6.3 7.4 22.9 1.4 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Baculo_PP31 PF05311.11 CDJ53681.1 - 4.4 6.7 16.9 5.2 6.5 16.9 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Neur_chan_memb PF02932.16 CDJ53681.1 - 5 7.1 16.6 5.2 7.0 16.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 CDJ53681.1 - 5.3 6.4 20.2 6.7 6.1 20.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4228 PF14009.6 CDJ53681.1 - 6.5 7.1 14.3 7.6 6.9 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) TrbI PF03743.14 CDJ53681.1 - 6.8 6.5 17.5 8.9 6.1 17.5 1.2 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein DUF4446 PF14584.6 CDJ53681.1 - 6.8 6.7 8.6 8.2 6.4 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Connexin PF00029.19 CDJ53681.1 - 7.5 6.2 15.4 8.7 6.0 15.4 1.1 1 0 0 1 1 1 0 Connexin DDHD PF02862.17 CDJ53681.1 - 7.9 6.6 18.7 11 6.1 18.7 1.2 1 0 0 1 1 1 0 DDHD domain NEMP PF10225.9 CDJ53681.1 - 8.4 6.0 8.0 9.1 5.9 8.0 1.0 1 0 0 1 1 1 0 NEMP family DUF4551 PF15087.6 CDJ53682.1 - 0.081 11.7 23.6 0.087 11.6 23.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOBP PF15279.6 CDJ53682.1 - 0.87 10.1 31.6 1.1 9.8 31.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 CDJ53682.1 - 1.9 7.1 30.0 2.4 6.7 30.0 1.2 1 0 0 1 1 1 0 Hamartin protein DUF5585 PF17823.1 CDJ53682.1 - 7.2 5.5 32.3 9.2 5.1 32.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) PA26 PF04636.13 CDJ53683.1 - 0.0027 16.7 17.8 0.0032 16.4 17.8 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Caldesmon PF02029.15 CDJ53683.1 - 0.093 11.5 36.8 0.12 11.2 36.8 1.0 1 0 0 1 1 1 0 Caldesmon CCSAP PF15748.5 CDJ53683.1 - 0.31 11.2 38.8 0.57 10.3 38.8 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4045 PF13254.6 CDJ53683.1 - 0.62 9.6 30.6 0.77 9.3 30.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.14 CDJ53683.1 - 0.63 8.3 28.5 0.79 7.9 28.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ53683.1 - 1 8.3 33.5 1.3 8.0 33.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF572 PF04502.13 CDJ53683.1 - 1.8 8.1 28.8 2.9 7.4 28.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.16 CDJ53683.1 - 2.1 8.3 29.1 3 7.8 29.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CAC1F_C PF16885.5 CDJ53683.1 - 4.5 6.8 24.2 6.5 6.3 24.2 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term SRP-alpha_N PF04086.13 CDJ53683.1 - 7.8 6.3 32.1 12 5.7 32.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BPL_N PF09825.9 CDJ53683.1 - 9.6 5.2 19.5 11 5.0 19.5 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Trp_oprn_chp PF09534.10 CDJ53685.1 - 0.27 11.0 12.9 0.41 10.4 12.9 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) BAF1_ABF1 PF04684.13 CDJ53685.1 - 0.9 8.5 32.1 1 8.3 32.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RskA PF10099.9 CDJ53685.1 - 5.7 7.2 38.8 12 6.1 38.8 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA ALG11_N PF15924.5 CDJ53687.1 - 2.4e-19 70.2 1.7 8.8e-08 32.4 0.1 5.1 3 1 1 5 5 5 3 ALG11 mannosyltransferase N-terminus Nha1_C PF08619.10 CDJ53687.1 - 0.015 14.5 0.1 0.015 14.5 0.1 4.6 3 1 1 4 4 4 0 Alkali metal cation/H+ antiporter Nha1 C terminus Shadoo PF14999.6 CDJ53687.1 - 1.6 8.8 12.8 1.3 9.1 0.5 3.0 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective pKID PF02173.17 CDJ53687.1 - 4.4 6.8 6.2 0.43 10.1 0.5 2.4 2 0 0 2 2 2 0 pKID domain Ribosomal_60s PF00428.19 CDJ53687.1 - 6.2 7.5 38.1 0.17 12.5 11.6 3.9 4 0 0 4 4 4 0 60s Acidic ribosomal protein CBFD_NFYB_HMF PF00808.23 CDJ53688.1 - 1.2e-05 25.4 0.5 3.3e-05 24.1 0.5 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDJ53688.1 - 0.00028 21.3 0.0 0.00028 21.3 0.0 2.2 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 SUIM_assoc PF16619.5 CDJ53688.1 - 0.00046 20.2 1.7 0.0011 18.9 1.7 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 RNA_pol_Rpc34 PF05158.12 CDJ53688.1 - 0.0019 17.6 0.2 0.0026 17.2 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit CENP-T_C PF15511.6 CDJ53688.1 - 0.013 15.6 1.0 0.025 14.7 1.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DUF4667 PF15700.5 CDJ53688.1 - 0.022 14.9 3.1 0.023 14.8 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Folliculin PF11704.8 CDJ53688.1 - 0.11 12.3 0.3 0.23 11.3 0.3 1.6 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport AMP-binding PF00501.28 CDJ53688.1 - 1.2 7.6 4.5 1.6 7.3 4.5 1.1 1 0 0 1 1 1 0 AMP-binding enzyme DUF3446 PF11928.8 CDJ53688.1 - 9.6 6.6 20.9 3.2 8.1 7.7 3.2 3 0 0 3 3 3 0 Early growth response N-terminal domain BUD22 PF09073.10 CDJ53689.1 - 0.00085 18.8 16.5 0.00085 18.8 16.5 4.7 4 2 0 4 4 4 2 BUD22 Fib_alpha PF08702.10 CDJ53690.1 - 6e-05 23.3 14.7 9.4e-05 22.6 1.9 2.9 2 2 0 2 2 2 1 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 CDJ53690.1 - 0.00029 21.1 26.0 0.0012 19.1 4.4 3.0 2 1 0 2 2 2 1 JNK_SAPK-associated protein-1 SR-25 PF10500.9 CDJ53690.1 - 0.0019 17.9 12.2 0.0035 17.0 12.2 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF1664 PF07889.12 CDJ53690.1 - 0.0046 17.0 18.6 0.94 9.5 0.6 3.9 2 2 1 4 4 4 3 Protein of unknown function (DUF1664) FliD_C PF07195.12 CDJ53690.1 - 0.0083 15.6 6.6 0.083 12.3 1.8 2.4 2 1 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus Syntaxin-6_N PF09177.11 CDJ53690.1 - 0.0093 16.5 19.2 2.9 8.5 1.0 3.8 1 1 3 4 4 4 3 Syntaxin 6, N-terminal ATG16 PF08614.11 CDJ53690.1 - 0.011 15.9 14.4 0.011 15.9 14.4 2.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF2746 PF10874.8 CDJ53690.1 - 0.021 15.3 1.4 47 4.5 0.0 3.7 3 1 0 4 4 3 0 Protein of unknown function (DUF2746) PRMT5 PF05185.16 CDJ53690.1 - 0.037 13.9 0.1 0.098 12.5 0.1 1.7 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase MCPVI PF02993.14 CDJ53690.1 - 0.037 13.8 7.5 1.5 8.6 2.0 2.3 1 1 0 2 2 2 0 Minor capsid protein VI BLOC1_2 PF10046.9 CDJ53690.1 - 0.049 13.9 12.4 5.6 7.3 1.0 4.4 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 CDJ53690.1 - 0.13 12.8 13.7 0.71 10.4 3.2 4.3 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 CDJ53690.1 - 0.2 12.0 17.2 0.34 11.2 0.4 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) DUF16 PF01519.16 CDJ53690.1 - 0.25 11.9 16.0 0.7 10.4 2.3 3.8 2 1 2 4 4 4 0 Protein of unknown function DUF16 RICH PF05062.12 CDJ53690.1 - 0.25 11.7 9.2 0.094 13.1 1.0 3.4 3 1 0 3 3 3 0 RICH domain Baculo_PEP_C PF04513.12 CDJ53690.1 - 0.43 10.6 9.5 1.1 9.3 1.4 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 CDJ53690.1 - 0.55 9.8 20.0 0.14 11.7 11.0 2.5 1 1 1 2 2 2 0 Intermediate filament protein SF-assemblin PF06705.11 CDJ53690.1 - 0.8 9.0 14.9 3.6 6.9 8.8 3.0 2 1 0 2 2 2 0 SF-assemblin/beta giardin MetOD2 PF18548.1 CDJ53690.1 - 1.3 9.2 12.1 1.1 9.4 0.1 3.7 2 1 2 4 4 4 0 Metanogen output domain 2 TSLP PF15216.6 CDJ53690.1 - 1.5 9.1 7.3 0.31 11.3 0.5 2.7 3 0 0 3 3 3 0 Thymic stromal lymphopoietin Lin-8 PF03353.15 CDJ53690.1 - 2.7 7.5 9.9 0.23 11.0 4.5 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF3347 PF11827.8 CDJ53690.1 - 3.6 7.7 11.3 2.4 8.3 6.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) FliD_N PF02465.18 CDJ53690.1 - 4.2 8.1 15.7 0.47 11.2 4.7 2.9 2 2 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus NSP2-B_epitope PF14757.6 CDJ53690.1 - 4.7 6.8 10.0 18 4.9 6.9 2.3 1 1 1 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein GLTSCR1 PF15249.6 CDJ53690.1 - 5.9 7.4 8.7 1.5 9.3 0.5 2.7 3 0 0 3 3 3 0 Conserved region of unknown function on GLTSCR protein FlxA PF14282.6 CDJ53690.1 - 6.9 6.7 33.2 0.14 12.1 3.2 3.5 2 1 1 3 3 3 0 FlxA-like protein Kinesin_assoc PF16183.5 CDJ53690.1 - 8.1 6.5 11.9 1.6e+02 2.4 11.9 2.4 1 1 0 1 1 1 0 Kinesin-associated TraG_N PF07916.11 CDJ53690.1 - 9.5 5.0 6.2 1.5 7.6 2.0 1.7 1 1 1 2 2 2 0 TraG-like protein, N-terminal region Mt_ATP-synt_D PF05873.12 CDJ53690.1 - 10 6.0 7.5 16 5.3 0.2 3.0 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) TFIIA PF03153.13 CDJ53691.1 - 0.0001 22.5 84.4 0.0021 18.2 66.4 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit EIF4E-T PF10477.9 CDJ53691.1 - 2.6 6.8 58.7 0.045 12.6 41.8 2.2 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PAT1 PF09770.9 CDJ53691.1 - 4.6 5.4 62.7 0.19 9.9 47.8 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.13 CDJ53692.1 - 0.0083 15.2 4.2 0.0099 15.0 4.2 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DUF4834 PF16118.5 CDJ53692.1 - 0.033 15.2 0.2 0.033 15.2 0.2 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ53692.1 - 0.076 11.8 5.4 0.9 8.2 3.7 2.2 2 0 0 2 2 2 0 Presenilin EOS1 PF12326.8 CDJ53692.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 N-glycosylation protein Mucin PF01456.17 CDJ53692.1 - 0.2 11.7 24.3 0.34 10.9 24.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Tic110 PF16940.5 CDJ53692.1 - 0.34 9.3 20.0 0.46 8.9 20.0 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter AUX_IAA PF02309.16 CDJ53692.1 - 0.46 10.3 2.2 0.72 9.7 2.2 1.4 1 0 0 1 1 1 0 AUX/IAA family EPL1 PF10513.9 CDJ53692.1 - 0.56 10.6 4.5 0.21 12.0 1.3 1.9 2 0 0 2 2 2 0 Enhancer of polycomb-like Band_3_cyto PF07565.13 CDJ53692.1 - 1.4 8.6 7.8 6.3 6.5 7.8 2.0 1 1 0 1 1 1 0 Band 3 cytoplasmic domain RLL PF10036.9 CDJ53692.1 - 2.1 8.1 16.2 0.032 14.1 8.9 1.7 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein RAB3GAP2_N PF14655.6 CDJ53692.1 - 3.5 6.8 6.6 0.53 9.5 2.1 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CPSF100_C PF13299.6 CDJ53692.1 - 4.6 7.4 7.3 11 6.2 7.3 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Roughex PF06020.11 CDJ53692.1 - 5.1 6.1 13.1 12 4.8 13.1 1.6 1 0 0 1 1 1 0 Drosophila roughex protein Lin-8 PF03353.15 CDJ53693.1 - 0.0031 17.2 0.6 0.0031 17.2 0.6 1.7 2 0 0 2 2 2 1 Ras-mediated vulval-induction antagonist Sugar_tr PF00083.24 CDJ53693.1 - 0.0094 14.9 0.7 0.015 14.2 0.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter ALMT PF11744.8 CDJ53693.1 - 0.11 11.4 5.8 0.17 10.7 5.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TRAPPC9-Trs120 PF08626.11 CDJ53693.1 - 0.6 7.4 10.5 0.83 6.9 10.5 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit SLC12 PF03522.15 CDJ53693.1 - 0.69 8.9 6.7 1 8.3 6.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 CDJ53693.1 - 1.5 8.0 12.1 0.12 11.6 6.9 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter MDFI PF15316.6 CDJ53693.1 - 2.9 7.9 10.5 0.31 11.1 5.4 1.9 2 0 0 2 2 2 0 MyoD family inhibitor CbtB PF09489.10 CDJ53694.1 - 0.13 12.4 0.2 0.13 12.4 0.2 2.1 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Metal_resist PF13801.6 CDJ53694.1 - 0.2 11.8 4.6 0.088 13.0 2.2 1.6 1 1 1 2 2 2 0 Heavy-metal resistance SMN PF06003.12 CDJ53694.1 - 2.4 7.3 8.1 3.2 6.9 8.1 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Secretin_N_2 PF07655.13 CDJ53694.1 - 3.1 8.4 14.0 2.1 8.9 12.2 1.6 2 0 0 2 2 2 0 Secretin N-terminal domain AAA_23 PF13476.6 CDJ53695.1 - 0.0035 17.9 7.2 0.0035 17.9 7.2 1.5 2 0 0 2 2 2 1 AAA domain LMBR1 PF04791.16 CDJ53695.1 - 8.5 5.2 9.2 9.2 5.0 9.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Activator_LAG-3 PF11498.8 CDJ53696.1 - 0.019 13.9 24.5 0.018 14.0 24.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ53696.1 - 0.045 13.3 25.1 0.047 13.3 25.1 1.1 1 0 0 1 1 1 0 Spt20 family Peptidase_S49_N PF08496.10 CDJ53696.1 - 0.22 11.6 7.6 0.26 11.4 7.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4400 PF14348.6 CDJ53696.1 - 0.34 10.4 10.2 0.41 10.1 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) AAA_23 PF13476.6 CDJ53696.1 - 0.4 11.1 8.5 0.41 11.1 8.5 1.1 1 0 0 1 1 1 0 AAA domain RskA PF10099.9 CDJ53696.1 - 0.41 10.9 33.5 0.47 10.7 33.5 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2232 PF09991.9 CDJ53696.1 - 0.41 9.8 5.9 0.47 9.6 5.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Folliculin PF11704.8 CDJ53696.1 - 0.56 10.1 7.1 0.58 10.0 7.1 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DivIC PF04977.15 CDJ53696.1 - 0.82 9.5 16.6 1.4 8.7 16.6 1.3 1 0 0 1 1 1 0 Septum formation initiator eIF-3_zeta PF05091.12 CDJ53696.1 - 2.5 7.0 11.8 2.5 7.0 11.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Dehydrin PF00257.19 CDJ53696.1 - 2.7 8.5 14.4 3.1 8.3 14.4 1.1 1 0 0 1 1 1 0 Dehydrin TFIIA PF03153.13 CDJ53696.1 - 3 7.7 34.8 3.2 7.6 34.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1980 PF09323.10 CDJ53696.1 - 3 7.7 7.0 3.3 7.6 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3450 PF11932.8 CDJ53696.1 - 5 6.4 30.7 5.8 6.2 30.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ADP_ribosyl_GH PF03747.14 CDJ53696.1 - 6.3 6.4 15.3 6.3 6.4 15.3 1.0 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Med15 PF09606.10 CDJ53696.1 - 6.3 5.3 28.0 7.4 5.1 28.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM199X PF15814.5 CDJ53696.1 - 6.8 5.6 12.7 7.5 5.5 12.7 1.0 1 0 0 1 1 1 0 Protein family FAM199X Pex14_N PF04695.13 CDJ53696.1 - 7.8 7.1 21.4 10 6.8 21.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pex14_N PF04695.13 CDJ53697.1 - 0.66 10.6 40.5 0.4 11.3 7.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IHABP4_N PF16174.5 CDJ53697.1 - 3.1 8.4 34.4 5.8 7.5 4.0 2.1 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Spore_coat_CotO PF14153.6 CDJ53697.1 - 9.3 6.1 42.3 7.8 6.4 8.6 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Fasciclin PF02469.22 CDJ53698.1 - 4e-05 23.8 0.2 7e-05 23.1 0.2 1.4 1 1 0 1 1 1 1 Fasciclin domain DDHD PF02862.17 CDJ53698.1 - 0.012 15.8 2.8 0.015 15.5 2.8 1.1 1 0 0 1 1 1 0 DDHD domain DUF3506 PF12014.8 CDJ53698.1 - 0.015 15.3 1.1 0.022 14.8 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Peptidase_S49_N PF08496.10 CDJ53698.1 - 0.027 14.5 5.9 0.042 13.9 5.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.16 CDJ53698.1 - 0.031 14.3 0.8 0.033 14.2 0.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ53698.1 - 0.033 14.0 5.3 0.042 13.7 5.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MCU PF04678.13 CDJ53698.1 - 0.09 12.9 2.7 0.11 12.5 2.7 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Saw1 PF11561.8 CDJ53698.1 - 0.093 12.3 7.7 0.12 11.9 7.7 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 AIF_C PF14721.6 CDJ53698.1 - 0.095 13.1 3.7 0.15 12.4 3.7 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Presenilin PF01080.17 CDJ53698.1 - 0.12 11.2 9.2 0.15 10.8 9.2 1.1 1 0 0 1 1 1 0 Presenilin OmpH PF03938.14 CDJ53698.1 - 0.15 12.4 30.5 0.23 11.8 30.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MMU163 PF17119.5 CDJ53698.1 - 0.15 11.2 1.3 0.21 10.7 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF3292 PF11696.8 CDJ53698.1 - 0.17 10.2 6.0 0.27 9.6 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) SpoIIP PF07454.11 CDJ53698.1 - 0.17 11.3 8.2 0.21 11.0 8.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF1764 PF08576.10 CDJ53698.1 - 0.19 12.7 5.5 0.29 12.1 5.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Connexin PF00029.19 CDJ53698.1 - 0.22 11.3 8.9 0.3 10.8 8.9 1.1 1 0 0 1 1 1 0 Connexin Cyclin_C PF02984.19 CDJ53698.1 - 0.36 10.9 4.8 1.1 9.4 4.8 1.8 1 0 0 1 1 1 0 Cyclin, C-terminal domain Gti1_Pac2 PF09729.9 CDJ53698.1 - 0.4 10.8 4.0 0.55 10.3 4.0 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family TFB6 PF17110.5 CDJ53698.1 - 0.43 10.3 5.0 0.6 9.8 5.0 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Es2 PF09751.9 CDJ53698.1 - 0.52 10.0 11.2 1 9.0 11.2 1.4 1 0 0 1 1 1 0 Nuclear protein Es2 DUF4746 PF15928.5 CDJ53698.1 - 0.71 9.2 5.3 0.89 8.9 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Serinc PF03348.15 CDJ53698.1 - 1.3 7.9 4.2 1.6 7.5 4.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ndc1_Nup PF09531.10 CDJ53698.1 - 1.5 7.5 6.6 1.9 7.1 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CLN3 PF02487.17 CDJ53698.1 - 1.5 7.8 6.1 2.1 7.3 6.1 1.1 1 0 0 1 1 1 0 CLN3 protein FAM60A PF15396.6 CDJ53698.1 - 1.8 8.5 6.3 2.5 8.1 6.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Sec62 PF03839.16 CDJ53698.1 - 2.1 7.8 5.5 2.8 7.4 5.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 STAC2_u1 PF16664.5 CDJ53698.1 - 2.2 8.7 8.2 3.8 8.0 8.2 1.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 V_ATPase_I PF01496.19 CDJ53698.1 - 2.2 6.1 10.4 2.8 5.7 10.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1631 PF07793.11 CDJ53698.1 - 2.5 6.4 32.5 3.4 6.0 32.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) ALMT PF11744.8 CDJ53698.1 - 3.1 6.5 6.0 3.7 6.3 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter ANXA2R PF15721.5 CDJ53698.1 - 3.3 8.2 14.6 4.9 7.6 14.6 1.2 1 0 0 1 1 1 0 Annexin-2 receptor CCSAP PF15748.5 CDJ53698.1 - 3.5 7.7 13.4 4.9 7.2 13.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated EIIBC-GUT_N PF03612.14 CDJ53698.1 - 3.7 7.3 7.2 5.7 6.6 7.2 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RSRP PF17069.5 CDJ53698.1 - 3.7 7.0 6.0 5.7 6.4 6.0 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CAF1 PF04857.20 CDJ53698.1 - 4.5 6.3 7.9 5.8 6.0 7.9 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease RED_N PF07808.13 CDJ53698.1 - 5.6 6.5 15.6 9.2 5.8 15.6 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF2992 PF11208.8 CDJ53698.1 - 6.7 7.0 19.5 9.6 6.5 19.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) MAJIN PF15077.6 CDJ53698.1 - 7.4 6.3 7.5 10 5.8 7.5 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF1980 PF09323.10 CDJ53698.1 - 7.5 6.4 7.2 12 5.8 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) YABBY PF04690.13 CDJ53698.1 - 8.7 6.9 8.4 12 6.4 8.4 1.2 1 0 0 1 1 1 0 YABBY protein OmpH PF03938.14 CDJ53699.1 - 0.011 16.1 14.0 0.011 16.1 14.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Nop53 PF07767.11 CDJ53699.1 - 0.11 11.9 12.5 0.14 11.5 12.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) AUX_IAA PF02309.16 CDJ53699.1 - 0.45 10.3 7.3 0.54 10.1 7.3 1.2 1 0 0 1 1 1 0 AUX/IAA family NEMP PF10225.9 CDJ53699.1 - 0.51 10.0 7.6 0.72 9.5 7.6 1.3 1 0 0 1 1 1 0 NEMP family DUF2464 PF10240.9 CDJ53699.1 - 0.55 9.8 5.6 0.73 9.4 5.6 1.4 1 0 0 1 1 1 0 Multivesicular body subunit 12 Serinc PF03348.15 CDJ53699.1 - 0.55 9.1 7.7 0.69 8.8 7.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Velvet PF11754.8 CDJ53699.1 - 0.57 10.1 19.6 0.088 12.7 15.8 1.5 1 1 1 2 2 2 0 Velvet factor Suf PF05843.14 CDJ53699.1 - 0.71 9.8 14.4 0.88 9.5 14.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ53699.1 - 1.1 9.3 9.6 1.8 8.6 9.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1387 PF07139.11 CDJ53699.1 - 2.1 8.0 13.3 3.6 7.2 13.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) RR_TM4-6 PF06459.12 CDJ53699.1 - 2.3 8.0 10.0 3 7.6 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RskA PF10099.9 CDJ53699.1 - 3 8.1 42.6 0.15 12.3 20.5 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA GREB1 PF15782.5 CDJ53699.1 - 3.2 4.8 20.6 3.6 4.6 20.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 CDJ53699.1 - 4.5 6.2 10.2 5.5 5.9 10.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 CDJ53699.1 - 4.8 5.2 12.0 5.7 4.9 12.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2681 PF10883.8 CDJ53699.1 - 5.5 7.5 21.3 0.88 10.0 11.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) V_ATPase_I PF01496.19 CDJ53699.1 - 6.8 4.5 8.4 8.2 4.2 8.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LCD1 PF09798.9 CDJ53699.1 - 8.3 4.8 13.4 11 4.3 13.4 1.3 1 1 0 1 1 1 0 DNA damage checkpoint protein PAT1 PF09770.9 CDJ53699.1 - 8.5 4.5 23.0 10 4.2 23.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 CDJ53700.1 - 1.1e-05 25.2 7.7 1.1e-05 25.2 7.7 6.3 4 1 1 5 5 5 3 Spt20 family AIF_C PF14721.6 CDJ53700.1 - 2.5 8.5 19.1 0.15 12.4 0.8 4.9 4 0 0 4 4 4 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SASRP1 PF15160.6 CDJ53701.1 - 0.38 10.4 5.7 1.2 8.7 5.7 1.8 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 Spt20 PF12090.8 CDJ53701.1 - 0.49 10.0 47.4 0.1 12.2 22.1 2.6 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ53701.1 - 0.58 9.0 40.2 0.5 9.2 19.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) EOS1 PF12326.8 CDJ53701.1 - 2.3 8.1 6.6 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 N-glycosylation protein PIEZO PF15917.5 CDJ53701.1 - 2.4 7.6 17.5 0.1 12.1 1.4 2.5 2 0 0 2 2 2 0 Piezo NST1 PF13945.6 CDJ53701.1 - 4.3 7.4 25.1 7 6.7 6.6 2.6 2 0 0 2 2 2 0 Salt tolerance down-regulator Shadoo PF14999.6 CDJ53702.1 - 0.0035 17.4 4.3 0.0038 17.3 4.3 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective DUF3824 PF12868.7 CDJ53702.1 - 0.011 16.4 11.2 0.014 16.1 11.2 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) RskA PF10099.9 CDJ53702.1 - 0.012 15.9 23.0 0.015 15.6 23.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ53702.1 - 0.076 14.0 4.4 0.077 14.0 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4179 PF13786.6 CDJ53702.1 - 0.16 12.4 5.5 0.2 12.1 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Coilin_N PF15862.5 CDJ53702.1 - 0.16 11.8 7.1 0.17 11.7 7.1 1.0 1 0 0 1 1 1 0 Coilin N-terminus DUF4064 PF13273.6 CDJ53702.1 - 0.17 12.2 0.9 0.2 11.9 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4820 PF16091.5 CDJ53702.1 - 0.17 11.2 5.3 0.19 11.1 5.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3446 PF11928.8 CDJ53702.1 - 0.22 11.8 1.9 0.26 11.6 1.9 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain Ocular_alb PF02101.15 CDJ53702.1 - 0.24 10.3 3.6 0.26 10.2 3.6 1.0 1 0 0 1 1 1 0 Ocular albinism type 1 protein AIF_C PF14721.6 CDJ53702.1 - 0.29 11.5 6.2 0.3 11.4 6.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FHIPEP PF00771.20 CDJ53702.1 - 0.39 9.1 8.1 0.4 9.1 8.1 1.0 1 0 0 1 1 1 0 FHIPEP family Spt20 PF12090.8 CDJ53702.1 - 0.4 10.2 20.8 0.37 10.4 20.8 1.0 1 0 0 1 1 1 0 Spt20 family EIIBC-GUT_N PF03612.14 CDJ53702.1 - 0.5 10.1 6.7 0.51 10.1 6.7 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2722 PF10846.8 CDJ53702.1 - 0.62 8.9 15.8 0.61 9.0 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Fungal_trans_2 PF11951.8 CDJ53702.1 - 0.93 8.2 6.6 1 8.1 6.6 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain RAB3GAP2_N PF14655.6 CDJ53702.1 - 1.1 8.5 9.4 1.2 8.3 9.4 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4228 PF14009.6 CDJ53702.1 - 1.2 9.5 6.5 1.3 9.4 6.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) CPSF100_C PF13299.6 CDJ53702.1 - 1.3 9.2 8.0 1.5 9.0 8.0 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal LIM_bind PF01803.16 CDJ53702.1 - 1.5 8.3 8.1 1.5 8.3 8.1 1.0 1 0 0 1 1 1 0 LIM-domain binding protein R_equi_Vir PF05526.11 CDJ53702.1 - 1.6 8.6 8.6 1.8 8.4 8.6 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein BAF1_ABF1 PF04684.13 CDJ53702.1 - 1.6 7.7 12.3 1.6 7.7 12.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ53702.1 - 1.7 8.6 22.8 1.9 8.4 22.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ53702.1 - 1.7 7.3 7.5 1.9 7.2 7.5 1.0 1 0 0 1 1 1 0 Presenilin DUF3450 PF11932.8 CDJ53702.1 - 4.8 6.4 21.4 5.2 6.3 21.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CCDC53 PF10152.9 CDJ53702.1 - 5.1 7.5 12.5 5.8 7.3 12.5 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3464 PF11947.8 CDJ53702.1 - 5.3 6.8 8.5 5.5 6.7 8.5 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 UPF0560 PF10577.9 CDJ53702.1 - 7.6 4.9 12.4 7.2 5.0 12.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PMSI1 PF15322.6 CDJ53702.1 - 8.4 5.7 11.3 9.1 5.6 11.3 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative ESM4 PF15952.5 CDJ53703.1 - 0.0085 16.5 5.9 0.0085 16.5 5.9 3.8 2 1 0 3 3 3 1 Enhancer of split M4 family PIG-S PF10510.9 CDJ53704.1 - 0.37 9.6 10.0 0.37 9.6 10.0 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Drf_GBD PF06371.13 CDJ53704.1 - 1.7 8.1 13.2 1.9 8.0 13.2 1.0 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF3464 PF11947.8 CDJ53704.1 - 3.6 7.3 7.0 3.5 7.4 7.0 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 KAP_NTPase PF07693.14 CDJ53704.1 - 9.9 5.3 10.1 11 5.2 10.1 1.0 1 0 0 1 1 1 0 KAP family P-loop domain MID_MedPIWI PF18296.1 CDJ53705.1 - 0.002 18.0 3.9 0.002 18.0 3.9 2.4 2 1 0 2 2 2 1 MID domain of medPIWI Sigma54_DBD PF04552.13 CDJ53705.1 - 0.012 15.3 1.8 0.029 14.1 1.8 1.6 1 0 0 1 1 1 0 Sigma-54, DNA binding domain TMEM208_SND2 PF05620.11 CDJ53705.1 - 0.024 14.4 0.6 0.1 12.3 0.6 2.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Chorein_N PF12624.7 CDJ53705.1 - 0.049 13.7 0.1 0.049 13.7 0.1 1.8 2 0 0 2 2 2 0 N-terminal region of Chorein or VPS13 DUF4199 PF13858.6 CDJ53705.1 - 0.25 11.7 2.2 1.1 9.6 2.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) V_ATPase_I PF01496.19 CDJ53705.1 - 0.75 7.6 7.2 3.8 5.3 2.7 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NEMP PF10225.9 CDJ53705.1 - 4.3 6.9 8.8 1.9 8.1 0.5 2.6 2 0 0 2 2 2 0 NEMP family SR-25 PF10500.9 CDJ53706.1 - 0.0078 15.9 34.5 0.036 13.7 11.8 3.1 2 1 0 3 3 3 3 Nuclear RNA-splicing-associated protein PC_rep PF01851.22 CDJ53707.1 - 2.9e-16 59.0 2.8 0.00026 21.3 0.0 5.3 4 0 0 4 4 4 4 Proteasome/cyclosome repeat SARAF PF06682.12 CDJ53707.1 - 0.0079 15.9 24.4 0.045 13.4 4.0 2.6 2 0 0 2 2 2 2 SOCE-associated regulatory factor of calcium homoeostasis DUF3801 PF12687.7 CDJ53707.1 - 0.013 15.5 1.0 0.013 15.5 1.0 3.7 3 1 0 3 3 2 0 Protein of unknown function (DUF3801) Velvet PF11754.8 CDJ53707.1 - 0.17 11.8 25.3 0.39 10.6 1.2 2.5 2 0 0 2 2 2 0 Velvet factor Caldesmon PF02029.15 CDJ53707.1 - 0.2 10.4 36.1 0.12 11.1 2.3 2.6 2 0 0 2 2 2 0 Caldesmon INSIG PF07281.12 CDJ53707.1 - 0.25 11.0 0.0 0.25 11.0 0.0 3.8 3 1 0 3 3 3 0 Insulin-induced protein (INSIG) Neur_chan_memb PF02932.16 CDJ53707.1 - 0.26 11.3 25.0 0.72 9.9 1.4 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ53707.1 - 0.96 8.1 50.4 0.061 12.1 7.3 3.2 3 0 0 3 3 3 0 Presenilin Utp14 PF04615.13 CDJ53707.1 - 1.3 7.5 63.9 0.21 10.1 5.0 3.3 3 0 0 3 3 3 0 Utp14 protein DUF2828 PF11443.8 CDJ53707.1 - 2 6.4 32.2 0.42 8.6 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Gti1_Pac2 PF09729.9 CDJ53707.1 - 5.3 7.1 35.0 0.039 14.0 1.6 3.0 3 0 0 3 3 3 0 Gti1/Pac2 family DEAD PF00270.29 CDJ53708.1 - 3.8e-44 150.5 0.0 6.8e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ53708.1 - 2.4e-22 79.4 0.0 2.6e-21 76.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ53708.1 - 0.0017 18.4 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Bromodomain PF00439.25 CDJ53709.1 - 0.00048 20.1 0.0 0.00076 19.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain Presenilin PF01080.17 CDJ53710.1 - 0.007 15.2 23.8 0.009 14.8 23.8 1.1 1 0 0 1 1 1 1 Presenilin Suf PF05843.14 CDJ53710.1 - 0.03 14.3 23.8 0.04 13.9 23.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) HC2 PF07382.11 CDJ53710.1 - 0.061 13.4 1.8 0.083 13.0 1.8 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Otopetrin PF03189.13 CDJ53710.1 - 0.064 12.1 11.9 0.097 11.5 11.9 1.3 1 0 0 1 1 1 0 Otopetrin SLC12 PF03522.15 CDJ53710.1 - 0.23 10.4 23.7 0.3 10.1 23.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 CDJ53710.1 - 0.3 10.6 26.8 0.37 10.3 26.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ndc1_Nup PF09531.10 CDJ53710.1 - 0.73 8.5 13.0 0.89 8.2 13.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2076 PF09849.9 CDJ53710.1 - 0.79 9.7 36.3 1.1 9.2 36.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Neur_chan_memb PF02932.16 CDJ53710.1 - 1.2 9.1 19.3 1.7 8.6 19.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDK5_activator PF03261.15 CDJ53710.1 - 2.4 7.6 21.6 3.2 7.2 21.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Spem1 PF15670.5 CDJ53710.1 - 2.5 7.6 23.6 3.9 7.0 23.6 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Membralin PF09746.9 CDJ53710.1 - 6.5 5.7 18.6 8.8 5.2 18.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein PPP4R2 PF09184.11 CDJ53711.1 - 1.2 8.6 29.3 1.8 8.1 29.3 1.3 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 CDJ53711.1 - 2.1 8.3 24.4 2.6 8.0 24.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRP-alpha_N PF04086.13 CDJ53711.1 - 2.4 8.0 28.6 3.6 7.4 28.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Raftlin PF15250.6 CDJ53711.1 - 3.5 6.3 23.4 5.1 5.7 23.4 1.1 1 0 0 1 1 1 0 Raftlin CDC27 PF09507.10 CDJ53711.1 - 3.9 6.7 38.2 5.6 6.2 38.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SR-25 PF10500.9 CDJ53711.1 - 6.2 6.4 31.5 1.4 8.5 5.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dicty_REP PF05086.12 CDJ53711.1 - 6.4 4.6 11.8 8.7 4.2 11.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF966 PF06136.13 CDJ53711.1 - 9.9 5.8 27.8 12 5.5 27.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DNA_primase_lrg PF04104.14 CDJ53712.1 - 0.057 12.8 0.4 0.089 12.2 0.4 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Raftlin PF15250.6 CDJ53712.1 - 0.89 8.2 10.0 1.3 7.7 10.0 1.3 1 0 0 1 1 1 0 Raftlin Utp14 PF04615.13 CDJ53712.1 - 1.4 7.4 12.6 1.9 7.0 12.6 1.1 1 0 0 1 1 1 0 Utp14 protein PA26 PF04636.13 CDJ53712.1 - 1.8 7.4 6.4 3.2 6.5 6.4 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SOBP PF15279.6 CDJ53712.1 - 3 8.4 16.9 4.7 7.7 16.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S64 PF08192.11 CDJ53712.1 - 5 5.5 20.3 6.5 5.1 20.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 GET2 PF08690.10 CDJ53712.1 - 9.6 5.8 15.1 14 5.2 15.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Spt20 PF12090.8 CDJ53713.1 - 0.21 11.2 25.2 0.23 11.0 25.2 1.1 1 0 0 1 1 1 0 Spt20 family Pap_E4 PF02711.14 CDJ53713.1 - 0.47 11.5 7.0 0.47 11.4 7.0 1.1 1 0 0 1 1 1 0 E4 protein MMR1 PF08505.10 CDJ53713.1 - 0.53 10.5 13.4 0.55 10.5 13.4 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Sporozoite_P67 PF05642.11 CDJ53713.1 - 1.2 7.1 7.6 1.2 7.1 7.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Afi1 PF07792.12 CDJ53713.1 - 1.7 9.1 7.3 2 8.9 7.3 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Eapp_C PF10238.9 CDJ53713.1 - 1.8 8.6 9.5 2.1 8.4 9.5 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein TFIIA PF03153.13 CDJ53713.1 - 2.1 8.2 26.2 2.3 8.1 26.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4770 PF15994.5 CDJ53713.1 - 2.3 8.4 8.4 2.2 8.5 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FAM176 PF14851.6 CDJ53713.1 - 2.5 7.8 7.1 2.8 7.6 7.1 1.1 1 0 0 1 1 1 0 FAM176 family DUF4366 PF14283.6 CDJ53713.1 - 3 7.9 7.8 3.7 7.6 7.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF702 PF05142.12 CDJ53713.1 - 5.1 7.6 13.6 6.1 7.3 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) ALMT PF11744.8 CDJ53713.1 - 5.3 5.7 7.6 5.9 5.6 7.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2722 PF10846.8 CDJ53713.1 - 5.5 5.8 21.3 6.4 5.6 21.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 CDJ53713.1 - 6.7 5.6 15.0 7.4 5.4 15.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FemAB PF02388.16 CDJ53713.1 - 8 5.2 11.4 7.6 5.3 11.4 1.0 1 0 0 1 1 1 0 FemAB family Connexin PF00029.19 CDJ53713.1 - 8.4 6.1 7.1 8.7 6.0 7.1 1.1 1 0 0 1 1 1 0 Connexin NPR3 PF03666.13 CDJ53713.1 - 8.5 5.0 11.0 9.3 4.9 11.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 CDJ53713.1 - 9.5 5.5 9.1 9.5 5.5 9.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paf1 PF03985.13 CDJ53713.1 - 9.7 5.1 14.1 11 4.9 14.1 1.0 1 0 0 1 1 1 0 Paf1 SID-1_RNA_chan PF13965.6 CDJ53714.1 - 0.14 10.5 12.5 0.19 10.1 12.5 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.7 CDJ53714.1 - 0.74 7.9 31.4 0.74 7.9 31.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 CDJ53714.1 - 1.5 7.5 31.3 1.6 7.4 31.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ53714.1 - 1.6 6.9 63.3 1.8 6.7 63.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 VIR_N PF15912.5 CDJ53714.1 - 3.7 7.1 20.8 5.3 6.6 20.8 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal CAC1F_C PF16885.5 CDJ53714.1 - 7.5 6.1 29.7 8.8 5.9 29.7 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term GAGA_bind PF06217.12 CDJ53714.1 - 9.3 6.4 34.6 11 6.1 34.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Spt20 PF12090.8 CDJ53715.1 - 0.0089 15.7 15.2 0.0089 15.7 15.2 1.1 1 0 0 1 1 1 1 Spt20 family EIIBC-GUT_N PF03612.14 CDJ53715.1 - 0.035 13.8 1.1 0.037 13.8 1.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Med15 PF09606.10 CDJ53715.1 - 0.067 11.9 17.6 0.072 11.8 17.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4834 PF16118.5 CDJ53715.1 - 0.078 13.9 4.0 0.081 13.9 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) UPF0560 PF10577.9 CDJ53715.1 - 0.17 10.3 5.4 0.17 10.3 5.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2722 PF10846.8 CDJ53715.1 - 0.23 10.4 13.4 0.22 10.4 13.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med3 PF11593.8 CDJ53715.1 - 0.23 10.6 13.5 0.23 10.6 13.5 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Activator_LAG-3 PF11498.8 CDJ53715.1 - 0.31 9.9 21.4 0.32 9.9 21.4 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ53715.1 - 0.38 10.7 12.6 0.35 10.8 12.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DivIC PF04977.15 CDJ53715.1 - 0.73 9.6 11.0 0.89 9.4 11.0 1.2 1 0 0 1 1 1 0 Septum formation initiator Androgen_recep PF02166.16 CDJ53715.1 - 1.3 7.8 15.1 1.2 7.8 15.1 1.0 1 0 0 1 1 1 0 Androgen receptor Mob1_phocein PF03637.17 CDJ53716.1 - 8.7e-12 45.4 0.0 3e-10 40.4 0.0 2.7 2 1 0 2 2 2 1 Mob1/phocein family CLN3 PF02487.17 CDJ53716.1 - 0.45 9.5 3.7 0.7 8.9 0.0 2.5 3 0 0 3 3 3 0 CLN3 protein S1 PF00575.23 CDJ53717.1 - 6.9e-12 45.5 0.7 1.6e-11 44.4 0.1 2.0 2 0 0 2 2 2 1 S1 RNA binding domain EIF_2_alpha PF07541.12 CDJ53717.1 - 4.4e-10 39.7 0.0 7.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit Phage_1_1 PF08200.11 CDJ53717.1 - 0.041 14.3 0.2 0.1 13.0 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein EXOSC1 PF10447.9 CDJ53717.1 - 0.064 13.9 0.2 0.2 12.3 0.2 1.9 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 OAD_gamma PF04277.13 CDJ53722.1 - 3.1 8.5 7.4 15 6.3 0.0 2.2 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Zip PF02535.22 CDJ53725.1 - 0.097 11.9 0.2 0.094 11.9 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MMR1 PF08505.10 CDJ53725.1 - 0.25 11.6 9.2 0.35 11.1 9.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Fer4_22 PF17179.4 CDJ53725.1 - 0.28 12.0 3.3 0.4 11.6 3.3 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Spt20 PF12090.8 CDJ53725.1 - 0.89 9.1 20.0 1.3 8.6 20.0 1.3 1 0 0 1 1 1 0 Spt20 family Lin-8 PF03353.15 CDJ53725.1 - 1.1 8.8 8.8 1.4 8.4 8.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mito_fiss_reg PF05308.11 CDJ53725.1 - 1.1 9.2 19.7 0.081 13.0 5.6 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator SOG2 PF10428.9 CDJ53725.1 - 1.4 8.0 12.6 1.9 7.6 12.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CDJ53725.1 - 2 7.1 9.3 2.6 6.7 9.0 1.4 2 0 0 2 2 2 0 Presenilin CPSF100_C PF13299.6 CDJ53725.1 - 3.1 8.0 5.8 4.7 7.4 5.8 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4551 PF15087.6 CDJ53725.1 - 4.1 6.1 10.1 5.4 5.7 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Connexin PF00029.19 CDJ53725.1 - 8.7 6.0 6.3 11 5.7 6.3 1.1 1 0 0 1 1 1 0 Connexin SelP_N PF04592.14 CDJ53725.1 - 9.2 5.6 19.0 13 5.1 19.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIF_alpha PF05793.12 CDJ53726.1 - 0.041 12.5 21.0 0.043 12.4 21.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.9 CDJ53726.1 - 0.13 10.8 31.8 0.16 10.5 31.8 1.2 1 0 0 1 1 1 0 Macoilin family DUF4647 PF15504.6 CDJ53726.1 - 0.51 9.4 38.4 0.53 9.3 38.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Sin_N PF04801.13 CDJ53726.1 - 0.55 9.4 52.4 0.57 9.3 52.4 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region CCSAP PF15748.5 CDJ53726.1 - 1.6 8.8 40.5 2 8.5 40.5 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SOBP PF15279.6 CDJ53726.1 - 1.7 9.2 33.0 1.9 9.0 33.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4628 PF15429.6 CDJ53726.1 - 1.7 8.3 27.2 2.5 7.7 27.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Apt1 PF10351.9 CDJ53726.1 - 1.8 7.3 28.0 2.4 6.9 28.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S64 PF08192.11 CDJ53726.1 - 3.9 5.9 36.0 4.3 5.7 36.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 PAP1 PF08601.10 CDJ53726.1 - 4.7 6.8 33.8 5.2 6.7 33.8 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 SOG2 PF10428.9 CDJ53726.1 - 6.3 5.9 38.3 7.2 5.7 38.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein AF-4 PF05110.13 CDJ53726.1 - 6.4 4.7 47.2 7.8 4.4 47.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Miga PF10265.9 CDJ53726.1 - 9.1 5.1 28.6 12 4.8 28.6 1.1 1 0 0 1 1 1 0 Mitoguardin TAF6_C PF07571.13 CDJ53727.1 - 9.7 6.6 7.0 1.4 9.3 2.2 2.1 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain FAM176 PF14851.6 CDJ53728.1 - 0.045 13.4 0.0 0.045 13.4 0.0 2.7 3 0 0 3 3 3 0 FAM176 family Sin_N PF04801.13 CDJ53729.1 - 0.0015 17.8 14.1 0.0016 17.7 14.1 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Tim54 PF11711.8 CDJ53729.1 - 0.0082 15.0 6.2 0.0089 14.9 6.2 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 CDJ53729.1 - 0.013 15.0 10.0 0.016 14.7 10.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SPX PF03105.19 CDJ53729.1 - 0.069 13.1 18.6 0.092 12.6 18.6 1.2 1 0 0 1 1 1 0 SPX domain EMC3_TMCO1 PF01956.16 CDJ53729.1 - 0.33 10.7 5.9 0.41 10.4 5.9 1.3 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4647 PF15504.6 CDJ53729.1 - 0.35 9.9 12.5 0.37 9.8 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) PepSY_TM PF03929.16 CDJ53729.1 - 0.36 10.5 2.5 0.38 10.4 2.5 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Sec62 PF03839.16 CDJ53729.1 - 0.42 10.1 5.1 0.5 9.8 5.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Hit1_C PF18268.1 CDJ53729.1 - 0.46 10.7 6.2 3.1 8.0 0.0 3.1 3 1 0 3 3 3 0 Hit1 C-terminal Exonuc_VII_L PF02601.15 CDJ53729.1 - 0.74 9.3 10.0 0.97 8.9 10.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lin-8 PF03353.15 CDJ53729.1 - 0.8 9.2 27.7 0.013 15.1 19.4 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF3464 PF11947.8 CDJ53729.1 - 0.98 9.2 11.0 1.8 8.3 11.0 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RR_TM4-6 PF06459.12 CDJ53729.1 - 1.6 8.5 13.7 2.6 7.8 13.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4770 PF15994.5 CDJ53729.1 - 1.9 8.7 13.7 3.2 8.0 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) CobT PF06213.12 CDJ53729.1 - 1.9 7.8 21.0 2.7 7.3 21.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.6 CDJ53729.1 - 3.3 7.3 10.7 2.3 7.9 8.6 1.8 3 0 0 3 3 3 0 FAM176 family DUF3408 PF11888.8 CDJ53729.1 - 3.6 7.7 15.6 6.3 6.9 15.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) RAP1 PF07218.11 CDJ53729.1 - 3.7 5.7 10.6 4.7 5.4 10.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.9 CDJ53729.1 - 4.2 5.5 22.1 4.9 5.3 22.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RPA43_OB PF17875.1 CDJ53729.1 - 4.5 7.9 12.6 8.3 7.1 12.6 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I MscS_TM PF12794.7 CDJ53729.1 - 7.9 5.2 7.8 12 4.6 7.8 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2500 PF10694.9 CDJ53729.1 - 8.6 6.9 19.4 64 4.1 0.0 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF2500) LSM PF01423.22 CDJ53733.1 - 6.1e-20 70.7 0.0 7.4e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CDJ53733.1 - 0.016 15.3 0.0 0.038 14.1 0.0 1.6 2 0 0 2 2 2 0 RimP C-terminal SH3 domain HydF_tetramer PF18133.1 CDJ53734.1 - 0.054 13.2 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain BRF1 PF07741.13 CDJ53734.1 - 0.15 12.4 4.5 0.23 11.8 4.5 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain MRP-L46 PF11788.8 CDJ53734.1 - 0.64 10.8 10.1 4 8.2 10.2 2.2 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 RskA PF10099.9 CDJ53735.1 - 0.0034 17.7 6.3 0.0034 17.7 6.3 32.0 5 4 20 26 26 26 6 Anti-sigma-K factor rskA RSS_P20 PF11757.8 CDJ53736.1 - 0.099 13.1 0.1 1 9.9 0.1 2.2 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Phostensin_N PF13916.6 CDJ53736.1 - 2.3 8.6 19.8 6.2 7.2 1.6 3.9 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal SUIM_assoc PF16619.5 CDJ53737.1 - 0.0002 21.4 6.5 0.0002 21.4 6.5 7.2 3 2 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ53737.1 - 0.0049 15.9 17.7 0.0049 15.9 17.7 4.1 3 1 0 3 3 3 2 Protein of unknown function (DUF2722) Caldesmon PF02029.15 CDJ53737.1 - 0.54 8.9 34.9 0.12 11.1 9.2 2.2 2 0 0 2 2 2 0 Caldesmon Nha1_C PF08619.10 CDJ53737.1 - 1.9 7.6 33.5 2.9 7.0 9.7 2.2 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Pkinase PF00069.25 CDJ53739.1 - 1e-05 25.1 0.1 0.03 13.7 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain SBP_bac_3 PF00497.20 CDJ53739.1 - 0.11 12.0 2.8 0.2 11.1 2.8 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 SUIM_assoc PF16619.5 CDJ53739.1 - 0.2 11.7 13.8 0.46 10.6 3.2 3.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Macoilin PF09726.9 CDJ53739.1 - 6.2 5.2 18.6 2.3 6.7 10.9 2.6 2 0 0 2 2 2 0 Macoilin family CDV3 PF15359.6 CDJ53740.1 - 8.3 6.9 12.3 13 6.3 7.5 2.5 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 PIG-X PF08320.12 CDJ53741.1 - 7e-12 45.7 0.1 4.5e-11 43.1 0.1 2.1 1 1 0 1 1 1 1 PIG-X / PBN1 Sporozoite_P67 PF05642.11 CDJ53742.1 - 0.00083 17.6 0.0 0.00083 17.6 0.0 4.5 2 2 1 3 3 3 1 Sporozoite P67 surface antigen RskA PF10099.9 CDJ53742.1 - 0.17 12.2 0.0 0.17 12.2 0.0 5.5 1 1 1 3 3 3 0 Anti-sigma-K factor rskA SNARE_assoc PF09335.11 CDJ53744.1 - 3.3e-08 34.0 3.7 1.3e-07 32.1 1.0 3.3 3 1 0 3 3 3 1 SNARE associated Golgi protein TFIIA PF03153.13 CDJ53744.1 - 0.0027 17.8 20.6 0.011 15.7 9.7 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ53744.1 - 0.0083 15.8 8.5 0.0083 15.8 8.5 2.2 2 0 0 2 2 2 2 Spt20 family Med15 PF09606.10 CDJ53744.1 - 0.055 12.2 20.2 0.021 13.5 7.7 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Arch_flagellin PF01917.16 CDJ53744.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Archaebacterial flagellin Dynein_AAA_lid PF17852.1 CDJ53744.1 - 0.11 12.6 0.2 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain DUF2722 PF10846.8 CDJ53744.1 - 0.47 9.3 15.9 0.39 9.6 6.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ53744.1 - 0.68 9.9 7.7 0.41 10.6 2.4 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 CDJ53744.1 - 1.8 9.6 4.2 13 6.8 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Pex14_N PF04695.13 CDJ53744.1 - 3.4 8.3 20.7 2.6 8.7 4.8 3.3 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CNDH2_C PF16858.5 CDJ53745.1 - 6e-05 23.1 5.0 9.6e-05 22.4 5.0 1.4 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term BUD22 PF09073.10 CDJ53745.1 - 0.0032 16.9 26.7 0.0032 16.9 26.7 1.6 2 0 0 2 2 1 1 BUD22 DUF2076 PF09849.9 CDJ53745.1 - 0.0032 17.5 22.8 0.0032 17.5 22.8 4.2 3 1 0 3 3 1 1 Uncharacterized protein conserved in bacteria (DUF2076) NARP1 PF12569.8 CDJ53745.1 - 0.019 13.9 9.7 0.036 13.0 9.7 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TerC PF03741.16 CDJ53745.1 - 0.1 12.3 0.2 0.31 10.7 0.2 1.8 1 0 0 1 1 1 0 Integral membrane protein TerC family Plasmodium_Vir PF05795.11 CDJ53745.1 - 0.13 11.7 15.2 0.29 10.5 15.2 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LETM1 PF07766.13 CDJ53745.1 - 0.13 11.6 4.7 0.23 10.8 4.7 1.4 1 0 0 1 1 1 0 LETM1-like protein VIR_N PF15912.5 CDJ53745.1 - 0.15 11.7 6.3 0.1 12.2 4.0 1.8 2 0 0 2 2 2 0 Virilizer, N-terminal DUF5523 PF17661.1 CDJ53745.1 - 0.35 10.5 18.6 0.71 9.5 18.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Asp-B-Hydro_N PF05279.11 CDJ53745.1 - 0.7 9.9 19.8 1.5 8.9 19.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4638 PF15472.6 CDJ53745.1 - 0.75 9.5 7.9 1.4 8.6 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF4471 PF14740.6 CDJ53745.1 - 0.77 8.9 7.4 1.2 8.2 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF4746 PF15928.5 CDJ53745.1 - 1.1 8.6 16.5 2.1 7.7 16.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) V_ATPase_I PF01496.19 CDJ53745.1 - 1.3 6.9 15.3 2.1 6.2 15.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lin-8 PF03353.15 CDJ53745.1 - 1.4 8.4 26.6 0.32 10.5 22.8 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Connexin PF00029.19 CDJ53745.1 - 1.6 8.5 10.0 3 7.5 10.0 1.5 1 0 0 1 1 1 0 Connexin TRAP_alpha PF03896.16 CDJ53745.1 - 1.7 7.8 11.4 3.1 6.9 11.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pinin_SDK_memA PF04696.13 CDJ53745.1 - 1.7 8.7 31.3 0.071 13.2 24.6 2.0 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DDRGK PF09756.9 CDJ53745.1 - 2.1 7.9 25.1 4.3 6.9 25.1 1.4 1 0 0 1 1 1 0 DDRGK domain PAT1 PF09770.9 CDJ53745.1 - 3.8 5.7 27.1 0.2 9.9 20.4 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SpoIIP PF07454.11 CDJ53745.1 - 4.7 6.6 20.7 0.29 10.6 15.5 1.5 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2457 PF10446.9 CDJ53745.1 - 5.2 6.1 23.6 0.95 8.5 19.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nop53 PF07767.11 CDJ53747.1 - 0.068 12.6 27.7 0.077 12.4 17.1 2.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) UPF0564 PF10595.9 CDJ53747.1 - 1.4 7.9 35.4 4.1 6.4 35.5 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0564 DUF2052 PF09747.9 CDJ53747.1 - 3.4 7.7 22.5 4.8 7.3 13.6 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) eIF-3_zeta PF05091.12 CDJ53747.1 - 5.3 5.9 28.7 0.25 10.3 18.7 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 CDJ53747.1 - 10 5.8 23.9 0.44 10.3 13.9 2.2 2 0 0 2 2 2 0 Connexin ALMT PF11744.8 CDJ53748.1 - 0.038 12.8 17.6 0.043 12.7 17.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 CDJ53748.1 - 0.088 12.6 29.5 0.097 12.5 29.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM76 PF16046.5 CDJ53748.1 - 0.12 11.7 26.4 0.15 11.4 26.4 1.0 1 0 0 1 1 1 0 FAM76 protein Tim54 PF11711.8 CDJ53748.1 - 0.16 10.7 20.0 0.19 10.5 20.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4045 PF13254.6 CDJ53748.1 - 0.29 10.7 26.7 0.33 10.5 26.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) HemX PF04375.14 CDJ53748.1 - 0.34 10.1 43.1 0.35 10.1 43.1 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Gti1_Pac2 PF09729.9 CDJ53748.1 - 0.37 10.9 22.4 0.47 10.5 22.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 CDJ53748.1 - 0.48 9.4 27.7 0.54 9.2 27.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CDJ53748.1 - 0.65 7.1 27.1 0.72 6.9 27.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Cellulose_synt PF03552.14 CDJ53748.1 - 0.65 8.4 8.6 0.73 8.2 8.6 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF3295 PF11702.8 CDJ53748.1 - 0.67 9.2 25.5 0.7 9.2 25.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) WTX PF09422.10 CDJ53748.1 - 0.86 8.6 20.0 0.97 8.4 20.0 1.0 1 0 0 1 1 1 0 WTX protein CSG2 PF16965.5 CDJ53748.1 - 0.95 8.3 11.4 1.3 7.9 11.4 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator eIF-3_zeta PF05091.12 CDJ53748.1 - 0.95 8.4 32.4 1.2 8.0 32.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Endostatin PF06482.11 CDJ53748.1 - 1.1 8.7 28.2 1.2 8.5 28.2 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PAT1 PF09770.9 CDJ53748.1 - 1.5 7.0 46.9 1.7 6.9 46.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ53748.1 - 1.6 7.8 14.9 1.7 7.8 14.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter LAP1C PF05609.12 CDJ53748.1 - 1.9 7.5 25.5 2.1 7.4 25.5 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF5427 PF10310.9 CDJ53748.1 - 2.1 7.2 29.1 2.4 7.0 29.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Plasmodium_Vir PF05795.11 CDJ53748.1 - 2.4 7.5 13.9 2.9 7.2 13.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pkinase_fungal PF17667.1 CDJ53748.1 - 2.9 6.5 13.8 3.2 6.4 13.8 1.1 1 0 0 1 1 1 0 Fungal protein kinase Neur_chan_memb PF02932.16 CDJ53748.1 - 3.1 7.8 23.7 3.7 7.6 23.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 CDJ53748.1 - 3.7 7.5 23.1 4.5 7.2 23.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PTPRCAP PF15713.5 CDJ53748.1 - 3.9 7.8 25.8 6.2 7.1 25.8 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SAGA-Tad1 PF12767.7 CDJ53748.1 - 4.2 7.0 24.5 4.8 6.8 24.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NPR3 PF03666.13 CDJ53748.1 - 4.3 6.0 27.2 5 5.8 27.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MAJIN PF15077.6 CDJ53748.1 - 4.4 7.0 21.5 5.5 6.7 21.5 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF3292 PF11696.8 CDJ53748.1 - 4.6 5.5 20.5 5.3 5.3 20.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) VIT1 PF01988.19 CDJ53748.1 - 4.9 7.0 11.8 7.1 6.4 11.8 1.3 1 0 0 1 1 1 0 VIT family MCM_bind PF09739.9 CDJ53748.1 - 4.9 5.5 25.4 5.6 5.3 25.4 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PA26 PF04636.13 CDJ53748.1 - 5 5.9 19.6 5.7 5.7 19.6 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2052 PF09747.9 CDJ53748.1 - 5.2 7.2 28.2 6 6.9 28.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CLN3 PF02487.17 CDJ53748.1 - 5.2 6.0 19.7 6.7 5.7 19.7 1.3 1 0 0 1 1 1 0 CLN3 protein Peptidase_S64 PF08192.11 CDJ53748.1 - 5.5 5.4 23.4 6.3 5.2 23.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Exonuc_VII_L PF02601.15 CDJ53748.1 - 5.6 6.4 26.0 6.1 6.3 26.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit CDC45 PF02724.14 CDJ53748.1 - 5.7 5.1 25.5 6.5 4.9 25.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DAG_kinase_N PF14513.6 CDJ53748.1 - 5.8 7.1 25.7 6.7 6.9 25.7 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Hydin_ADK PF17213.3 CDJ53748.1 - 5.8 7.1 25.6 9 6.5 25.6 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MMR1 PF08505.10 CDJ53748.1 - 5.9 7.1 33.6 10 6.3 33.6 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Hid1 PF12722.7 CDJ53748.1 - 6 4.9 29.6 7 4.6 29.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4569 PF15133.6 CDJ53748.1 - 6.9 6.3 29.1 8.2 6.0 29.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Membralin PF09746.9 CDJ53748.1 - 7 5.6 18.6 8.2 5.3 18.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein BORG_CEP PF14957.6 CDJ53748.1 - 7.2 7.8 20.3 11 7.2 20.3 1.3 1 0 0 1 1 1 0 Cdc42 effector CCSAP PF15748.5 CDJ53748.1 - 7.4 6.7 34.3 8.9 6.4 34.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF913 PF06025.12 CDJ53748.1 - 7.7 5.4 17.5 10 5.0 17.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2828 PF11443.8 CDJ53748.1 - 8.1 4.4 24.8 9.5 4.2 24.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Rtf2 PF04641.12 CDJ53748.1 - 8.1 5.7 26.2 9.7 5.5 26.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1387 PF07139.11 CDJ53748.1 - 8.4 6.0 30.1 10 5.7 30.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) XRN_M PF17846.1 CDJ53748.1 - 8.5 5.2 20.2 9.6 5.0 20.2 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Dapper PF15268.6 CDJ53748.1 - 8.6 5.1 33.6 9.7 4.9 33.6 1.0 1 0 0 1 1 1 0 Dapper LptF_LptG PF03739.14 CDJ53748.1 - 9 5.0 9.6 12 4.7 9.6 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Lin-8 PF03353.15 CDJ53748.1 - 9.7 5.7 36.5 12 5.4 36.5 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Skp1_POZ PF03931.15 CDJ53750.1 - 9.2e-20 70.6 0.2 1.8e-19 69.7 0.2 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 CDJ53750.1 - 2.8e-11 43.4 0.8 1.9e-10 40.6 0.8 2.2 1 1 0 1 1 1 1 Skp1 family, dimerisation domain RNA_pol_Rpc34 PF05158.12 CDJ53751.1 - 7.5e-36 124.2 0.0 9e-35 120.6 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit UBA_3 PF09288.10 CDJ53751.1 - 0.051 13.4 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain GCFC PF07842.12 CDJ53752.1 - 6.3e-28 98.2 16.9 7.1e-25 88.2 1.5 3.5 4 0 0 4 4 4 2 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 CDJ53752.1 - 4.4e-10 39.3 2.0 1.4e-09 37.7 2.0 1.9 1 0 0 1 1 1 1 G-patch domain Sin_N PF04801.13 CDJ53752.1 - 2e-05 24.0 0.0 2e-05 24.0 0.0 5.3 3 1 1 4 4 4 2 Sin-like protein conserved region ERCC4 PF02732.15 CDJ53753.1 - 5.2e-08 33.2 4.7 5.2e-08 33.2 4.7 4.3 3 1 0 3 3 3 1 ERCC4 domain Spt20 PF12090.8 CDJ53753.1 - 0.0079 15.8 14.3 0.0079 15.8 14.3 5.2 4 1 1 5 5 5 2 Spt20 family AAA_23 PF13476.6 CDJ53753.1 - 0.068 13.7 11.3 0.87 10.1 1.8 3.3 3 0 0 3 3 3 0 AAA domain eIF-3_zeta PF05091.12 CDJ53753.1 - 6.7 5.6 31.8 2.5 7.0 1.4 3.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AP3D1 PF06375.11 CDJ53754.1 - 0.0033 17.7 3.9 0.0033 17.7 3.9 4.4 4 1 0 4 4 4 1 AP-3 complex subunit delta-1 DUF2722 PF10846.8 CDJ53754.1 - 0.0067 15.4 2.7 0.0067 15.4 2.7 5.1 4 1 1 5 5 5 3 Protein of unknown function (DUF2722) PBP1_TM PF14812.6 CDJ53754.1 - 0.032 14.6 1.4 0.032 14.6 1.4 4.3 4 1 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_17 PF00332.18 CDJ53754.1 - 0.049 13.2 0.1 17 4.9 0.0 2.7 2 1 0 3 3 3 0 Glycosyl hydrolases family 17 Ribosomal_60s PF00428.19 CDJ53754.1 - 0.34 11.5 0.0 0.34 11.5 0.0 6.7 5 2 1 6 6 6 0 60s Acidic ribosomal protein Utp14 PF04615.13 CDJ53754.1 - 0.44 9.1 33.2 1 7.9 8.5 2.2 2 0 0 2 2 2 0 Utp14 protein RR_TM4-6 PF06459.12 CDJ53754.1 - 1.8 8.3 40.5 1.1 9.0 14.6 4.1 4 0 0 4 4 4 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.13 CDJ53757.1 - 0.00075 20.2 10.1 0.00075 20.2 10.1 11.5 10 3 3 13 13 13 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sin_N PF04801.13 CDJ53757.1 - 0.0016 17.7 18.9 0.0016 17.7 18.9 6.3 6 0 0 6 6 6 4 Sin-like protein conserved region Presenilin PF01080.17 CDJ53757.1 - 0.0021 16.9 1.6 0.0021 16.9 1.6 7.3 7 1 0 7 7 7 3 Presenilin SUIM_assoc PF16619.5 CDJ53757.1 - 0.0099 15.9 0.9 0.0099 15.9 0.9 15.2 7 5 2 9 9 9 3 Unstructured region C-term to UIM in Ataxin3 Metallophos PF00149.28 CDJ53760.1 - 9.3e-07 29.5 0.0 0.00018 22.1 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase SPX PF03105.19 CDJ53760.1 - 0.0018 18.3 17.1 0.0018 18.3 17.1 2.3 2 0 0 2 2 2 1 SPX domain Spt20 PF12090.8 CDJ53760.1 - 0.052 13.2 51.2 0.038 13.6 0.7 3.2 3 0 0 3 3 3 0 Spt20 family Presenilin PF01080.17 CDJ53760.1 - 1.1 7.9 25.3 0.12 11.1 5.6 2.9 3 0 0 3 3 3 0 Presenilin RAB3GAP2_N PF14655.6 CDJ53761.1 - 4.4 6.5 10.9 2.4 7.3 2.3 3.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus LRR_4 PF12799.7 CDJ53762.1 - 1e-10 41.6 13.2 4.3e-05 23.8 0.2 3.8 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ53762.1 - 2e-10 40.2 12.4 7.1e-07 28.9 4.3 3.4 3 0 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 CDJ53762.1 - 1.2e-08 34.7 0.3 1.2e-08 34.7 0.3 3.0 1 1 2 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.6 CDJ53762.1 - 0.00028 20.7 9.7 0.22 11.7 0.7 4.4 4 0 0 4 4 4 2 Leucine Rich repeat Dicty_REP PF05086.12 CDJ53762.1 - 3.5 5.5 8.1 5.8 4.8 8.1 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Dapper PF15268.6 CDJ53762.1 - 6.3 5.5 42.9 2.5 6.8 39.3 1.8 2 0 0 2 2 2 0 Dapper Pkinase PF00069.25 CDJ53763.1 - 1.6e-40 139.2 0.0 2.4e-26 92.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ53763.1 - 4.1e-18 65.6 0.0 1.1e-12 47.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDJ53763.1 - 1.3e-06 28.5 3.1 3.5e-05 23.8 0.3 3.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ53763.1 - 3.1e-05 23.4 0.0 0.15 11.3 0.1 2.9 3 0 0 3 3 3 2 Kinase-like PIP49_C PF12260.8 CDJ53763.1 - 0.00017 21.3 0.2 0.0003 20.5 0.2 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 SPX PF03105.19 CDJ53763.1 - 0.0073 16.3 0.8 0.0073 16.3 0.8 2.3 2 0 0 2 2 2 1 SPX domain Pkinase_fungal PF17667.1 CDJ53763.1 - 0.057 12.2 0.2 0.057 12.2 0.2 2.5 2 1 1 3 3 3 0 Fungal protein kinase TFIIA PF03153.13 CDJ53763.1 - 3.4 7.6 35.9 0.16 11.9 12.6 2.6 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit PUF PF00806.19 CDJ53764.1 - 1.6e-44 147.1 2.4 9.2e-07 28.2 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 CDJ53764.1 - 0.019 15.3 0.6 0.9 9.9 0.1 3.5 2 2 1 3 3 3 0 CPL (NUC119) domain CCDC53 PF10152.9 CDJ53764.1 - 0.064 13.7 0.2 0.064 13.7 0.2 7.3 4 3 0 5 5 5 0 Subunit CCDC53 of WASH complex ATG22 PF11700.8 CDJ53765.1 - 0.072 11.7 1.2 0.13 10.9 1.2 1.3 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like LCD1 PF09798.9 CDJ53765.1 - 0.087 11.3 2.6 0.11 11.0 2.6 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein MAT1 PF06391.13 CDJ53765.1 - 0.28 11.0 11.2 0.24 11.2 8.3 1.9 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Ribosomal_60s PF00428.19 CDJ53765.1 - 0.51 10.9 8.9 4.6 7.9 5.6 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein PPP4R2 PF09184.11 CDJ53765.1 - 0.63 9.6 6.2 0.85 9.1 6.2 1.3 1 0 0 1 1 1 0 PPP4R2 RAP1 PF07218.11 CDJ53765.1 - 1.2 7.3 8.2 1.4 7.1 8.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1345 PF07077.11 CDJ53765.1 - 1.9 8.1 8.6 7.1 6.3 7.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1345) SWI-SNF_Ssr4 PF08549.10 CDJ53765.1 - 2.5 6.6 14.2 3.2 6.3 14.2 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SR-25 PF10500.9 CDJ53766.1 - 1.9 8.1 40.1 1.2 8.7 22.6 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Caldesmon PF02029.15 CDJ53766.1 - 3.7 6.2 47.0 4.7 5.8 47.0 1.2 1 0 0 1 1 1 0 Caldesmon PAP1 PF08601.10 CDJ53766.1 - 7.5 6.2 38.9 10 5.7 38.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Spt20 PF12090.8 CDJ53767.1 - 0.0014 18.3 6.2 0.0019 17.9 6.2 1.2 1 0 0 1 1 1 1 Spt20 family SUIM_assoc PF16619.5 CDJ53767.1 - 0.04 14.0 9.3 0.04 14.0 9.3 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PIG-P PF08510.12 CDJ53767.1 - 0.23 11.4 0.0 0.42 10.5 0.0 1.6 2 0 0 2 2 2 0 PIG-P MIase PF02426.16 CDJ53767.1 - 0.31 11.2 0.1 0.31 11.2 0.1 2.6 2 1 0 2 2 2 0 Muconolactone delta-isomerase TFIIA PF03153.13 CDJ53767.1 - 3 7.7 20.5 4.6 7.1 20.5 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DEAD_assoc PF08494.11 CDJ53767.1 - 3.8 7.3 11.7 4.6 7.0 1.4 2.1 2 0 0 2 2 2 0 DEAD/H associated RskA PF10099.9 CDJ53768.1 - 0.0077 16.5 0.0 0.0077 16.5 0.0 13.7 2 2 6 8 8 8 1 Anti-sigma-K factor rskA DUF572 PF04502.13 CDJ53769.1 - 0.5 9.9 15.1 0.76 9.3 15.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4179 PF13786.6 CDJ53769.1 - 0.77 10.3 6.3 0.62 10.6 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) PAN_4 PF14295.6 CDJ53770.1 - 1.5e-16 60.0 9.7 4.4e-07 29.7 0.4 3.4 3 0 0 3 3 3 3 PAN domain Sporozoite_P67 PF05642.11 CDJ53770.1 - 0.00082 17.6 6.0 0.00082 17.6 6.0 8.0 3 2 5 9 9 9 2 Sporozoite P67 surface antigen Adaptin_binding PF10199.9 CDJ53770.1 - 0.11 13.1 0.0 0.11 13.1 0.0 14.8 1 1 3 4 4 4 0 Alpha and gamma adaptin binding protein p34 PAN_2 PF08276.11 CDJ53770.1 - 0.78 9.9 13.0 0.63 10.2 0.8 4.1 3 0 0 3 3 3 0 PAN-like domain UL73_N PF12522.8 CDJ53771.1 - 0.79 9.5 13.2 1.9 8.3 13.2 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal RskA PF10099.9 CDJ53772.1 - 0.0041 17.4 1.0 0.0041 17.4 1.0 20.9 5 5 10 15 15 15 1 Anti-sigma-K factor rskA HEAT PF02985.22 CDJ53772.1 - 1.4 9.4 9.2 14 6.2 0.4 5.1 3 0 0 3 3 3 0 HEAT repeat Herpes_ORF11 PF04797.13 CDJ53773.1 - 0.14 10.9 2.7 0.25 10.1 2.7 1.3 1 0 0 1 1 1 0 Herpesvirus dUTPase protein RskA PF10099.9 CDJ53773.1 - 0.18 12.1 44.6 1.8e+04 -13.1 44.6 2.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ53773.1 - 0.86 9.2 42.4 0.068 12.8 16.9 2.1 2 0 0 2 2 2 0 Spt20 family SPX PF03105.19 CDJ53773.1 - 1.5 8.6 19.2 2.4 8.0 19.2 1.3 1 0 0 1 1 1 0 SPX domain DUF2722 PF10846.8 CDJ53773.1 - 7.4 5.4 33.5 0.2 10.6 12.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TCP PF03634.13 CDJ53773.1 - 8.8 6.9 23.5 10 6.7 4.6 2.1 2 0 0 2 2 2 0 TCP family transcription factor Cytomega_UL84 PF06284.11 CDJ53777.1 - 0.0014 17.2 0.1 0.0024 16.4 0.1 1.3 1 0 0 1 1 1 1 Cytomegalovirus UL84 protein Radial_spoke PF04712.12 CDJ53778.1 - 8.2e-68 229.5 6.0 4.1e-67 227.2 0.0 3.8 1 1 1 2 2 1 1 Radial spokehead-like protein DUF4667 PF15700.5 CDJ53778.1 - 0.0012 19.0 10.5 0.0012 19.0 10.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ53778.1 - 0.014 15.0 13.1 0.037 13.6 13.1 1.6 1 0 0 1 1 1 0 Spt20 family Ecl1 PF12855.7 CDJ53778.1 - 0.015 16.4 23.8 0.037 15.2 15.3 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins DDHD PF02862.17 CDJ53778.1 - 0.09 12.9 4.1 0.096 12.8 2.1 2.0 2 0 0 2 2 2 0 DDHD domain Lin-8 PF03353.15 CDJ53778.1 - 0.13 11.8 13.8 0.018 14.6 6.4 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Totivirus_coat PF05518.11 CDJ53778.1 - 0.38 8.8 6.1 0.58 8.1 6.1 1.2 1 0 0 1 1 1 0 Totivirus coat protein Apt1 PF10351.9 CDJ53778.1 - 0.43 9.4 18.4 0.67 8.7 12.5 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Miga PF10265.9 CDJ53778.1 - 0.46 9.4 8.6 5.9 5.7 8.0 2.0 2 0 0 2 2 2 0 Mitoguardin Ndc1_Nup PF09531.10 CDJ53778.1 - 0.66 8.6 14.0 0.069 11.8 8.7 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 CDJ53778.1 - 0.99 8.5 24.8 0.47 9.6 17.9 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein DUF1645 PF07816.11 CDJ53778.1 - 1.5 9.3 33.4 0.2 12.2 14.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1645) SARAF PF06682.12 CDJ53778.1 - 1.7 8.3 19.9 0.27 10.9 10.9 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1635 PF07795.11 CDJ53778.1 - 4.3 7.1 14.5 1.6 8.5 9.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) SR-25 PF10500.9 CDJ53778.1 - 5.4 6.6 48.5 0.085 12.5 3.9 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ53779.1 - 8.4e-05 22.3 27.2 0.00011 21.9 27.2 1.4 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ53779.1 - 0.00073 18.6 23.0 0.00085 18.4 23.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ53779.1 - 0.0025 17.9 32.7 0.0034 17.4 32.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4471 PF14740.6 CDJ53779.1 - 0.0036 16.6 1.7 0.0037 16.5 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) SpoIIP PF07454.11 CDJ53779.1 - 0.0059 16.1 9.1 0.0064 16.0 9.1 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Peptidase_C58 PF03543.14 CDJ53779.1 - 0.047 13.4 10.8 0.057 13.1 10.8 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen SLC12 PF03522.15 CDJ53779.1 - 0.047 12.7 7.7 0.049 12.7 7.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ53779.1 - 0.053 13.4 8.9 0.056 13.3 8.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EPL1 PF10513.9 CDJ53779.1 - 0.054 13.9 10.3 0.065 13.6 10.3 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like CDC45 PF02724.14 CDJ53779.1 - 0.059 11.7 5.1 0.059 11.7 5.1 1.0 1 0 0 1 1 1 0 CDC45-like protein XRN_M PF17846.1 CDJ53779.1 - 0.086 11.8 3.8 0.1 11.5 3.8 1.0 1 0 0 1 1 1 0 Xrn1 helical domain MMR1 PF08505.10 CDJ53779.1 - 0.1 12.8 13.4 0.13 12.6 13.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FAM60A PF15396.6 CDJ53779.1 - 0.11 12.5 5.0 0.12 12.4 5.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF2151 PF10221.9 CDJ53779.1 - 0.14 10.7 5.1 0.16 10.5 5.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator FAM176 PF14851.6 CDJ53779.1 - 0.15 11.8 3.0 0.17 11.5 3.0 1.2 1 0 0 1 1 1 0 FAM176 family Band_3_cyto PF07565.13 CDJ53779.1 - 0.16 11.7 7.6 0.17 11.6 7.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4770 PF15994.5 CDJ53779.1 - 0.2 11.9 12.3 0.23 11.7 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) SET PF00856.28 CDJ53779.1 - 0.23 11.8 1.7 0.28 11.6 1.7 1.2 1 0 0 1 1 1 0 SET domain Miff PF05644.11 CDJ53779.1 - 0.24 11.0 11.2 0.29 10.7 11.2 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Rtf2 PF04641.12 CDJ53779.1 - 0.26 10.6 10.9 0.33 10.3 10.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Gti1_Pac2 PF09729.9 CDJ53779.1 - 0.26 11.3 7.7 0.33 11.0 7.7 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Otopetrin PF03189.13 CDJ53779.1 - 0.29 9.9 1.7 0.3 9.8 1.7 1.1 1 0 0 1 1 1 0 Otopetrin NARP1 PF12569.8 CDJ53779.1 - 0.3 10.0 9.0 0.37 9.7 9.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MCM_bind PF09739.9 CDJ53779.1 - 0.51 8.7 10.5 0.63 8.4 10.5 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor MDM10 PF12519.8 CDJ53779.1 - 0.51 9.1 7.1 0.53 9.1 7.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Dicty_REP PF05086.12 CDJ53779.1 - 0.54 8.2 3.0 0.57 8.1 3.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Macoilin PF09726.9 CDJ53779.1 - 0.66 8.5 9.5 0.81 8.2 9.5 1.1 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 CDJ53779.1 - 0.68 9.8 17.3 0.82 9.5 17.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ALMT PF11744.8 CDJ53779.1 - 0.69 8.7 6.5 0.73 8.6 6.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 CDJ53779.1 - 0.81 8.4 16.8 0.96 8.1 16.8 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CDJ53779.1 - 0.86 8.8 4.1 0.99 8.6 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1644 PF07800.12 CDJ53779.1 - 0.87 9.6 8.9 0.14 12.2 4.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) MAP65_ASE1 PF03999.12 CDJ53779.1 - 0.98 8.0 18.0 1.2 7.8 18.0 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) EMC3_TMCO1 PF01956.16 CDJ53779.1 - 1 9.1 8.1 1.2 8.8 8.1 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Endostatin PF06482.11 CDJ53779.1 - 1 8.7 11.7 1.2 8.6 11.7 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CCSAP PF15748.5 CDJ53779.1 - 1.1 9.4 18.5 1.6 8.9 18.5 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Miga PF10265.9 CDJ53779.1 - 1.2 8.0 10.6 1.5 7.7 10.6 1.0 1 0 0 1 1 1 0 Mitoguardin Lin-8 PF03353.15 CDJ53779.1 - 1.3 8.5 19.3 1.5 8.3 19.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ53779.1 - 1.4 7.7 11.1 1.6 7.5 11.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain eIF-3_zeta PF05091.12 CDJ53779.1 - 1.4 7.8 17.1 1.8 7.5 17.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ABC2_membrane_2 PF12679.7 CDJ53779.1 - 1.4 8.1 3.9 1.9 7.7 3.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein PAT1 PF09770.9 CDJ53779.1 - 1.6 6.9 25.6 1.7 6.8 25.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.11 CDJ53779.1 - 1.7 7.1 9.6 1.9 6.9 9.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 EIIBC-GUT_N PF03612.14 CDJ53779.1 - 1.7 8.3 13.3 2.9 7.6 13.3 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF1387 PF07139.11 CDJ53779.1 - 1.7 8.3 14.6 2 8.1 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) OATP PF03137.20 CDJ53779.1 - 1.8 6.7 6.0 1.9 6.6 6.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF913 PF06025.12 CDJ53779.1 - 1.9 7.4 8.1 2 7.3 8.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tim54 PF11711.8 CDJ53779.1 - 2.2 7.0 17.1 2.7 6.7 17.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TMEM171 PF15471.6 CDJ53779.1 - 2.4 7.1 12.1 3.4 6.6 12.1 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Neur_chan_memb PF02932.16 CDJ53779.1 - 2.4 8.2 10.2 2.8 7.9 10.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GNAT_acetyltr_2 PF13718.6 CDJ53779.1 - 2.5 7.5 7.8 3.2 7.1 7.8 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF4551 PF15087.6 CDJ53779.1 - 2.7 6.7 17.4 3.2 6.5 17.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Paf1 PF03985.13 CDJ53779.1 - 2.8 6.9 17.5 3.7 6.5 17.5 1.1 1 0 0 1 1 1 0 Paf1 YABBY PF04690.13 CDJ53779.1 - 3.3 8.3 13.4 3.6 8.1 12.9 1.3 1 1 0 1 1 1 0 YABBY protein Hid1 PF12722.7 CDJ53779.1 - 3.4 5.7 13.6 3.5 5.6 13.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein G0-G1_switch_2 PF15103.6 CDJ53779.1 - 3.8 8.0 10.0 6.6 7.2 10.0 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 TERB2 PF15101.6 CDJ53779.1 - 4.3 7.3 21.0 7.7 6.5 21.0 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2457 PF10446.9 CDJ53779.1 - 4.8 6.2 18.4 5.8 5.9 18.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Peptidase_S49_N PF08496.10 CDJ53779.1 - 5.1 7.1 11.4 7.1 6.7 11.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Coilin_N PF15862.5 CDJ53779.1 - 5.3 6.8 17.1 9.1 6.1 17.1 1.3 1 0 0 1 1 1 0 Coilin N-terminus WTX PF09422.10 CDJ53779.1 - 5.5 5.9 16.3 6.3 5.7 16.3 1.1 1 0 0 1 1 1 0 WTX protein Mitofilin PF09731.9 CDJ53779.1 - 6 5.6 25.7 7.7 5.2 25.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Connexin PF00029.19 CDJ53779.1 - 6.9 6.4 11.1 9 6.0 11.1 1.1 1 0 0 1 1 1 0 Connexin UPF0560 PF10577.9 CDJ53779.1 - 7.2 5.0 21.1 9.6 4.6 21.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MMU163 PF17119.5 CDJ53779.1 - 7.6 5.6 8.4 13 4.9 8.4 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis SCAI PF12070.8 CDJ53779.1 - 8.8 5.1 12.3 11 4.7 12.3 1.0 1 0 0 1 1 1 0 Protein SCAI DUF4834 PF16118.5 CDJ53779.1 - 8.9 7.3 16.8 15 6.6 16.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFB6 PF17110.5 CDJ53779.1 - 9.3 6.0 8.9 12 5.6 8.9 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Rrn6 PF10214.9 CDJ53779.1 - 9.6 4.5 30.3 11 4.3 30.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF2828 PF11443.8 CDJ53779.1 - 9.9 4.1 13.4 12 3.8 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SDA1 PF05285.12 CDJ53780.1 - 0.0025 17.3 27.8 0.0033 16.9 27.8 1.3 1 0 0 1 1 1 1 SDA1 DUF4470 PF14737.6 CDJ53780.1 - 0.0062 16.7 12.7 0.66 10.2 11.3 3.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4470) Hid1 PF12722.7 CDJ53780.1 - 0.029 12.5 32.7 0.037 12.2 32.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 CDJ53780.1 - 0.2 9.9 29.8 0.31 9.3 29.8 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3381 PF11861.8 CDJ53780.1 - 0.33 10.7 46.1 0.12 12.1 5.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Hamartin PF04388.12 CDJ53780.1 - 0.36 9.5 29.3 0.42 9.2 29.3 1.1 1 0 0 1 1 1 0 Hamartin protein DUF2052 PF09747.9 CDJ53780.1 - 0.4 10.8 43.2 0.42 10.7 2.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF3995 PF13160.6 CDJ53780.1 - 0.85 10.0 15.7 0.63 10.4 13.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) DUF3040 PF11239.8 CDJ53780.1 - 0.89 9.9 11.9 8.5 6.7 10.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Miga PF10265.9 CDJ53780.1 - 5 6.0 25.8 2.8 6.8 3.7 2.0 2 0 0 2 2 2 0 Mitoguardin AF-4 PF05110.13 CDJ53781.1 - 0.00049 18.4 4.8 0.0006 18.1 4.8 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein RskA PF10099.9 CDJ53781.1 - 0.0081 16.5 0.5 0.0087 16.4 0.5 1.0 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF45 PF01863.17 CDJ53781.1 - 0.017 15.2 0.5 0.021 14.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 Pox_D5 PF03288.16 CDJ53781.1 - 0.094 13.2 0.4 0.13 12.8 0.4 1.2 1 0 0 1 1 1 0 Poxvirus D5 protein-like Pep1_7 PF17232.2 CDJ53781.1 - 0.22 12.0 7.6 5.3 7.6 0.1 2.1 2 0 0 2 2 2 0 Elicitor peptide 1-7 IMUP PF15761.5 CDJ53781.1 - 1.4 9.7 15.3 0.13 13.0 10.4 1.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF4701 PF15773.5 CDJ53781.1 - 2.5 7.0 12.3 3.1 6.7 12.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4701) Chorion_2 PF03964.15 CDJ53781.1 - 2.6 8.9 9.4 1.9 9.4 6.4 1.9 2 0 0 2 2 2 0 Chorion family 2 DUF2786 PF10979.8 CDJ53781.1 - 4.6 7.2 8.5 8.5 6.4 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) TMEM51 PF15345.6 CDJ53783.1 - 2 8.2 11.3 2.7 7.8 11.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Presenilin PF01080.17 CDJ53783.1 - 4.1 6.1 12.7 5.3 5.7 12.7 1.0 1 0 0 1 1 1 0 Presenilin CSG2 PF16965.5 CDJ53783.1 - 4.9 6.0 5.5 5.4 5.9 5.5 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Folate_carrier PF01770.18 CDJ53783.1 - 8.8 4.9 8.3 3.2 6.4 5.8 1.5 1 1 1 2 2 2 0 Reduced folate carrier AF-4 PF05110.13 CDJ53784.1 - 8.1 4.4 52.9 4.4 5.3 17.2 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Orf78 PF06024.12 CDJ53785.1 - 0.031 14.6 1.4 0.051 13.9 1.4 1.3 1 0 0 1 1 1 0 Orf78 (ac78) TFIIA PF03153.13 CDJ53785.1 - 0.094 12.7 17.3 0.1 12.6 17.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GMP_PDE_delta PF05351.11 CDJ53785.1 - 0.24 11.5 2.1 0.34 11.0 2.1 1.1 1 0 0 1 1 1 0 GMP-PDE, delta subunit Mak10 PF04112.13 CDJ53785.1 - 0.37 10.3 4.8 0.62 9.6 4.8 1.3 1 1 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase EIIBC-GUT_N PF03612.14 CDJ53785.1 - 0.39 10.4 1.5 0.51 10.1 1.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RskA PF10099.9 CDJ53785.1 - 0.51 10.6 12.9 9.1 6.5 12.8 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA TERB2 PF15101.6 CDJ53785.1 - 0.77 9.8 7.2 1 9.4 7.2 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4834 PF16118.5 CDJ53785.1 - 2.6 9.1 6.0 3.9 8.5 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AAA_23 PF13476.6 CDJ53785.1 - 9.6 6.7 13.6 12 6.3 13.6 1.1 1 0 0 1 1 1 0 AAA domain TraT PF05818.12 CDJ53786.1 - 0.0022 17.7 3.7 0.0026 17.5 3.7 1.0 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein DUF4667 PF15700.5 CDJ53786.1 - 0.034 14.3 12.8 0.034 14.2 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ53786.1 - 0.67 9.8 12.2 0.7 9.8 12.2 1.0 1 0 0 1 1 1 0 SPX domain RSRP PF17069.5 CDJ53786.1 - 0.69 9.4 22.9 0.66 9.5 22.9 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Lin-8 PF03353.15 CDJ53786.1 - 1.3 8.5 3.9 1.3 8.5 3.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ53786.1 - 1.4 7.7 10.3 1.3 7.8 10.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain TraG-D_C PF12696.7 CDJ53786.1 - 3.2 7.7 9.2 4.2 7.4 9.2 1.2 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG AF-4 PF05110.13 CDJ53786.1 - 3.4 5.6 26.3 3 5.8 26.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 CDJ53786.1 - 3.7 7.1 36.2 5.6 6.5 36.2 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SARAF PF06682.12 CDJ53786.1 - 4.2 6.9 11.6 4.8 6.7 11.6 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF515 PF04415.12 CDJ53786.1 - 5.6 5.2 15.7 4.5 5.5 15.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MCM PF00493.23 CDJ53787.1 - 1.4e-81 272.8 0.0 2.9e-81 271.8 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDJ53787.1 - 3.1e-14 52.9 0.0 1.3e-13 50.9 0.0 2.1 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDJ53787.1 - 1.3e-13 51.2 2.4 1.3e-13 51.2 2.4 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ53787.1 - 1.7e-05 24.3 1.1 0.0072 15.7 0.0 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI DUF1645 PF07816.11 CDJ53787.1 - 0.0015 19.2 3.0 0.0015 19.2 3.0 7.9 6 2 1 7 7 7 3 Protein of unknown function (DUF1645) AAA_5 PF07728.14 CDJ53787.1 - 0.0015 18.5 0.0 0.004 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ53787.1 - 0.0026 17.6 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 CDJ53787.1 - 0.035 14.5 0.0 0.2 12.1 0.0 2.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Nop53 PF07767.11 CDJ53790.1 - 0.074 12.4 30.8 0.088 12.2 30.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) BAF1_ABF1 PF04684.13 CDJ53790.1 - 0.15 11.1 19.0 0.17 10.9 19.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CCSAP PF15748.5 CDJ53790.1 - 0.36 11.0 31.3 0.48 10.5 31.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated VIR_N PF15912.5 CDJ53790.1 - 0.62 9.6 13.4 0.73 9.4 13.4 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Membralin PF09746.9 CDJ53790.1 - 1.4 7.9 15.3 1.6 7.7 15.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein XAP5 PF04921.14 CDJ53790.1 - 1.4 8.7 19.7 2.3 8.0 19.7 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator PAT1 PF09770.9 CDJ53790.1 - 1.9 6.7 43.9 2.1 6.5 43.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2052 PF09747.9 CDJ53790.1 - 2.2 8.4 27.7 2.7 8.1 27.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) MIIP PF15734.5 CDJ53790.1 - 2.3 7.6 25.2 2.8 7.3 25.2 1.1 1 0 0 1 1 1 0 Migration and invasion-inhibitory SLC12 PF03522.15 CDJ53790.1 - 3.2 6.7 27.4 3.7 6.5 27.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CDK5_activator PF03261.15 CDJ53790.1 - 4.3 6.8 26.0 5.1 6.5 26.0 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PPP4R2 PF09184.11 CDJ53790.1 - 4.6 6.7 16.9 5.5 6.5 16.9 1.2 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 CDJ53790.1 - 5.1 5.3 22.4 6.3 5.0 22.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SOBP PF15279.6 CDJ53790.1 - 6.4 7.3 29.2 7.6 7.0 29.2 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein SR-25 PF10500.9 CDJ53791.1 - 0.00052 19.7 1.5 0.00052 19.7 1.5 16.3 14 2 2 17 17 17 3 Nuclear RNA-splicing-associated protein RICTOR_N PF14664.6 CDJ53791.1 - 0.31 10.0 13.5 0.18 10.8 1.6 4.6 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term RskA PF10099.9 CDJ53792.1 - 0.0016 18.8 13.1 0.0016 18.8 13.1 11.4 2 2 5 7 7 7 2 Anti-sigma-K factor rskA DUF4199 PF13858.6 CDJ53793.1 - 0.0011 19.4 2.5 0.0011 19.4 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF4199) Ribosomal_60s PF00428.19 CDJ53793.1 - 0.002 18.7 1.7 0.002 18.7 1.7 1.6 2 0 0 2 2 2 1 60s Acidic ribosomal protein RskA PF10099.9 CDJ53793.1 - 0.004 17.5 6.9 0.013 15.8 6.9 1.7 1 1 0 1 1 1 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ53793.1 - 0.0065 17.4 0.7 0.0065 17.4 0.7 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4834) FAM176 PF14851.6 CDJ53793.1 - 0.028 14.1 0.5 0.05 13.3 0.5 1.4 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 CDJ53793.1 - 0.035 13.3 1.4 0.046 12.9 1.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FHIPEP PF00771.20 CDJ53793.1 - 0.092 11.2 1.2 0.12 10.9 1.2 1.1 1 0 0 1 1 1 0 FHIPEP family SID-1_RNA_chan PF13965.6 CDJ53793.1 - 0.22 9.9 0.2 0.27 9.6 0.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HemX PF04375.14 CDJ53793.1 - 0.46 9.7 19.2 0.64 9.2 19.2 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spec3 PF15795.5 CDJ53793.1 - 0.74 10.4 6.8 0.16 12.5 2.2 2.1 1 1 1 2 2 2 0 Ectodermal ciliogenesis protein AIF_C PF14721.6 CDJ53793.1 - 0.87 9.9 5.8 3.4 8.0 5.8 1.9 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TFIIA PF03153.13 CDJ53793.1 - 1.6 8.7 27.9 2.3 8.1 27.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit G0-G1_switch_2 PF15103.6 CDJ53793.1 - 2.5 8.6 7.1 0.26 11.8 1.4 2.0 1 1 1 2 2 2 0 G0/G1 switch protein 2 PepSY_2 PF13670.6 CDJ53793.1 - 8 6.5 13.0 0.24 11.5 6.4 1.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain CobT PF06213.12 CDJ53794.1 - 1.3 8.4 29.1 1.4 8.3 29.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT V_ATPase_I PF01496.19 CDJ53794.1 - 3.2 5.5 22.9 3.3 5.5 22.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3381 PF11861.8 CDJ53794.1 - 4.6 7.0 26.8 5.2 6.8 26.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CLN3 PF02487.17 CDJ53794.1 - 6.6 5.7 16.0 6.5 5.7 16.0 1.0 1 0 0 1 1 1 0 CLN3 protein Auxin_canalis PF05703.11 CDJ53795.1 - 0.00013 22.0 16.2 0.00014 21.9 16.2 1.1 1 0 0 1 1 1 1 Auxin canalisation LptF_LptG PF03739.14 CDJ53795.1 - 0.00089 18.2 5.2 0.001 18.0 5.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG V_ATPase_I PF01496.19 CDJ53795.1 - 0.0021 16.1 15.3 0.0023 16.0 15.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Lin-8 PF03353.15 CDJ53795.1 - 0.0034 17.0 24.3 0.0039 16.8 24.3 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Hamartin PF04388.12 CDJ53795.1 - 0.019 13.7 20.8 0.023 13.4 20.8 1.1 1 0 0 1 1 1 0 Hamartin protein VIT1 PF01988.19 CDJ53795.1 - 0.033 14.1 10.4 0.053 13.4 10.4 1.4 1 0 0 1 1 1 0 VIT family Ndc1_Nup PF09531.10 CDJ53795.1 - 0.039 12.7 24.3 0.051 12.3 24.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4407 PF14362.6 CDJ53795.1 - 0.043 13.2 39.3 0.074 12.4 39.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 CDJ53795.1 - 0.054 13.6 19.5 0.071 13.2 19.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.6 CDJ53795.1 - 0.076 11.8 21.1 0.09 11.6 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF572 PF04502.13 CDJ53795.1 - 0.15 11.6 20.9 0.18 11.4 20.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC45 PF02724.14 CDJ53795.1 - 0.35 9.1 17.5 0.44 8.8 17.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Exonuc_VII_L PF02601.15 CDJ53795.1 - 0.49 9.9 26.6 0.62 9.6 26.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LAP1C PF05609.12 CDJ53795.1 - 0.54 9.3 24.6 0.73 8.9 24.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nha1_C PF08619.10 CDJ53795.1 - 0.93 8.6 28.8 1.1 8.4 28.8 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Pex14_N PF04695.13 CDJ53795.1 - 0.94 10.1 57.6 8.1 7.1 36.6 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 CDJ53795.1 - 1.1 7.4 52.1 1.3 7.2 52.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GET2 PF08690.10 CDJ53795.1 - 1.2 8.8 28.1 1.7 8.2 28.1 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Membralin PF09746.9 CDJ53795.1 - 1.3 8.0 13.0 1.7 7.6 13.0 1.4 1 0 0 1 1 1 0 Tumour-associated protein Pkinase_fungal PF17667.1 CDJ53795.1 - 1.8 7.2 10.4 2.2 6.9 10.4 1.2 1 0 0 1 1 1 0 Fungal protein kinase Trypan_PARP PF05887.11 CDJ53795.1 - 1.9 8.5 8.4 0.16 12.0 1.4 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) GREB1 PF15782.5 CDJ53795.1 - 2.4 5.2 30.3 3 4.9 30.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Draxin PF15550.6 CDJ53795.1 - 3.3 7.5 19.4 4.2 7.2 19.4 1.1 1 0 0 1 1 1 0 Draxin SWI-SNF_Ssr4 PF08549.10 CDJ53795.1 - 3.6 6.1 31.6 4 5.9 31.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) FAM60A PF15396.6 CDJ53795.1 - 4.2 7.3 26.4 6 6.8 26.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4045 PF13254.6 CDJ53795.1 - 5 6.7 30.1 6.2 6.4 30.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Het-C PF07217.11 CDJ53795.1 - 6.4 5.2 14.7 7.3 5.0 14.7 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C MRP-S27 PF10037.9 CDJ53795.1 - 6.7 5.5 28.7 8.5 5.1 28.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Rer1 PF03248.13 CDJ53795.1 - 6.9 6.4 5.7 1 9.1 0.1 2.1 1 1 1 2 2 2 0 Rer1 family Activator_LAG-3 PF11498.8 CDJ53796.1 - 0.0029 16.6 20.2 0.003 16.6 20.2 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 FAM60A PF15396.6 CDJ53796.1 - 0.023 14.7 1.7 0.023 14.7 1.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SelP_N PF04592.14 CDJ53796.1 - 0.024 14.0 4.9 0.026 13.9 4.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAM199X PF15814.5 CDJ53796.1 - 0.048 12.7 8.6 0.059 12.4 8.6 1.1 1 0 0 1 1 1 0 Protein family FAM199X AIF_C PF14721.6 CDJ53796.1 - 0.052 13.9 1.3 0.059 13.7 1.3 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PIG-U PF06728.13 CDJ53796.1 - 0.061 12.4 0.1 0.074 12.1 0.1 1.1 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U TFIIA PF03153.13 CDJ53796.1 - 0.067 13.2 29.0 0.078 13.0 29.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.3 CDJ53796.1 - 0.17 12.1 11.8 0.22 11.8 11.8 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SID-1_RNA_chan PF13965.6 CDJ53796.1 - 0.23 9.8 0.6 0.27 9.6 0.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Connexin PF00029.19 CDJ53796.1 - 0.29 10.9 1.9 0.32 10.7 1.9 1.1 1 0 0 1 1 1 0 Connexin eIF-3_zeta PF05091.12 CDJ53796.1 - 0.35 9.8 8.0 0.35 9.8 8.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1980 PF09323.10 CDJ53796.1 - 0.37 10.7 5.2 0.47 10.3 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Neur_chan_memb PF02932.16 CDJ53796.1 - 0.41 10.7 4.2 0.46 10.5 4.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region R_equi_Vir PF05526.11 CDJ53796.1 - 0.51 10.2 11.6 0.67 9.8 11.6 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein TraV PF09676.10 CDJ53796.1 - 0.56 11.2 13.9 0.77 10.7 13.9 1.2 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Pex14_N PF04695.13 CDJ53796.1 - 0.58 10.8 19.3 0.83 10.3 19.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PP31 PF05311.11 CDJ53796.1 - 0.66 9.4 7.2 0.76 9.2 7.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) BAF1_ABF1 PF04684.13 CDJ53796.1 - 0.67 8.9 13.1 0.8 8.7 13.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.14 CDJ53796.1 - 0.72 9.8 10.2 0.82 9.6 10.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Helicase_RecD PF05127.14 CDJ53796.1 - 0.89 9.4 7.4 1 9.2 7.4 1.1 1 0 0 1 1 1 0 Helicase CPSF100_C PF13299.6 CDJ53796.1 - 0.94 9.6 6.7 1.1 9.4 6.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.15 CDJ53796.1 - 0.96 8.3 3.6 1.1 8.1 3.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ctr PF04145.15 CDJ53796.1 - 1.1 9.9 3.1 1.4 9.6 3.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family TERB2 PF15101.6 CDJ53796.1 - 1.4 9.0 9.4 1.5 8.8 9.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Peptidase_S15 PF02129.18 CDJ53796.1 - 1.5 8.3 11.2 1.7 8.2 11.2 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Presenilin PF01080.17 CDJ53796.1 - 1.8 7.3 11.3 1.9 7.1 11.3 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ53796.1 - 2 6.6 18.1 2.2 6.5 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Roughex PF06020.11 CDJ53796.1 - 3.3 6.7 7.5 3.5 6.6 7.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein OmpH PF03938.14 CDJ53796.1 - 4.1 7.8 23.2 5.1 7.4 23.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4770 PF15994.5 CDJ53796.1 - 6.2 7.0 12.5 8.2 6.6 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) RXLR PF16810.5 CDJ53796.1 - 6.2 7.3 9.5 10 6.6 9.4 1.4 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Ndc1_Nup PF09531.10 CDJ53796.1 - 6.8 5.3 10.0 7.2 5.2 10.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RskA PF10099.9 CDJ53797.1 - 6.4e-05 23.3 0.1 6.4e-05 23.3 0.1 9.0 3 2 2 6 6 6 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ53797.1 - 0.0013 17.8 13.5 0.0013 17.8 13.5 4.8 3 2 0 4 4 4 1 Protein of unknown function (DUF2722) DUF936 PF06075.12 CDJ53798.1 - 0.019 13.9 38.3 0.023 13.6 38.3 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Spt20 PF12090.8 CDJ53799.1 - 0.0009 18.9 8.0 0.0009 18.9 8.0 2.1 2 0 0 2 2 2 1 Spt20 family DUF2722 PF10846.8 CDJ53799.1 - 0.0055 15.7 6.1 0.0055 15.7 6.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) RPOL_N PF14700.6 CDJ53799.1 - 0.025 14.0 10.9 0.031 13.7 9.2 1.8 2 1 0 2 2 2 0 DNA-directed RNA polymerase N-terminal Herpes_UL32 PF06070.11 CDJ53799.1 - 0.14 9.9 1.5 0.18 9.5 1.5 1.3 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF3371 PF11851.8 CDJ53799.1 - 0.16 13.1 6.7 0.33 12.1 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) DUF2973 PF11189.8 CDJ53799.1 - 0.44 10.7 4.5 2.4 8.3 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) DUF4813 PF16072.5 CDJ53799.1 - 0.48 10.0 19.5 0.69 9.5 19.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF3381 PF11861.8 CDJ53799.1 - 2.8 7.7 10.8 0.16 11.7 5.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) OmpH PF03938.14 CDJ53799.1 - 3.3 8.1 21.2 1.9 8.8 10.4 2.7 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) RskA PF10099.9 CDJ53799.1 - 6.7 7.0 36.3 1.4e+03 -0.6 36.2 2.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ53799.1 - 8.4 6.3 31.6 30 4.5 31.6 1.8 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC_tran PF00005.27 CDJ53801.1 - 3.2e-08 34.2 1.9 3.2e-08 34.2 1.9 4.2 4 1 0 4 4 4 1 ABC transporter BAF1_ABF1 PF04684.13 CDJ53801.1 - 0.0036 16.5 4.3 0.0036 16.5 4.3 5.4 4 1 0 5 5 5 1 BAF1 / ABF1 chromatin reorganising factor NYN PF01936.18 CDJ53801.1 - 0.0055 17.2 0.3 0.0055 17.2 0.3 3.0 4 0 0 4 4 4 1 NYN domain Shadoo PF14999.6 CDJ53801.1 - 0.016 15.3 1.3 0.016 15.3 1.3 9.7 5 4 4 9 9 9 0 Shadow of prion protein, neuroprotective SR-25 PF10500.9 CDJ53801.1 - 0.017 14.8 1.2 0.017 14.8 1.2 6.5 6 1 0 6 6 6 0 Nuclear RNA-splicing-associated protein AAA_29 PF13555.6 CDJ53801.1 - 0.017 14.8 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ53801.1 - 0.025 14.5 0.0 0.025 14.5 0.0 3.4 5 0 0 5 5 5 0 RsgA GTPase rRNA_processing PF08524.11 CDJ53801.1 - 0.029 14.4 0.5 0.029 14.4 0.5 5.8 6 0 0 6 6 6 0 rRNA processing MMR_HSR1 PF01926.23 CDJ53801.1 - 0.09 12.9 0.4 1.3 9.1 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase Peptidase_S49_N PF08496.10 CDJ53801.1 - 6.8 6.7 40.3 3.9 7.5 2.5 5.5 5 0 0 5 5 5 0 Peptidase family S49 N-terminal DUF4820 PF16091.5 CDJ53802.1 - 0.0049 16.3 12.3 0.0049 16.3 12.3 4.3 3 1 0 3 3 3 2 Domain of unknown function (DUF4820) WBP-1 PF11669.8 CDJ53802.1 - 0.052 14.2 0.9 0.052 14.2 0.9 5.4 3 1 1 4 4 4 0 WW domain-binding protein 1 AF-4 PF05110.13 CDJ53802.1 - 7.1 4.6 82.2 1.5 6.8 73.7 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Secretin_N_2 PF07655.13 CDJ53803.1 - 0.27 11.8 10.6 0.53 10.9 10.6 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain PRIMA1 PF16101.5 CDJ53803.1 - 2.3 8.3 9.0 7.4 6.6 8.4 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RskA PF10099.9 CDJ53804.1 - 1.6e-07 31.8 0.7 1.6e-07 31.8 0.7 3.2 1 1 2 3 3 3 1 Anti-sigma-K factor rskA PAT1 PF09770.9 CDJ53804.1 - 0.0061 14.9 6.6 0.0067 14.8 6.6 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 MMR1 PF08505.10 CDJ53804.1 - 1 9.6 8.4 1.6 8.9 8.4 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GREB1 PF15782.5 CDJ53804.1 - 6.5 3.7 11.1 8.5 3.3 11.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RskA PF10099.9 CDJ53805.1 - 6.8e-06 26.5 6.5 6.8e-06 26.5 6.5 4.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ53805.1 - 0.037 13.6 3.4 0.058 13.0 3.4 1.2 1 0 0 1 1 1 0 Spt20 family DUF294 PF03445.13 CDJ53805.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 SR-25 PF10500.9 CDJ53805.1 - 0.16 11.5 18.6 1.2 8.8 14.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 CDJ53805.1 - 2.1 8.2 8.7 3.6 7.4 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) CCDC106 PF15794.5 CDJ53805.1 - 3.5 7.3 5.7 5.9 6.5 5.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF755 PF05501.11 CDJ53805.1 - 3.9 7.8 25.8 0.8 10.0 16.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ53806.1 - 0.16 11.6 8.1 0.19 11.3 8.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CDJ53806.1 - 8.4 6.9 9.7 1.3 9.6 5.5 1.7 1 1 1 2 2 2 0 Dehydrin OmpH PF03938.14 CDJ53807.1 - 0.042 14.2 0.1 0.075 13.4 0.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4168 PF13767.6 CDJ53807.1 - 0.057 14.6 2.2 0.28 12.4 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) HetR_C PF18460.1 CDJ53807.1 - 0.069 13.1 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain Phage_sheath_1C PF17482.2 CDJ53807.1 - 0.15 12.1 0.8 0.31 11.0 0.2 1.8 2 0 0 2 2 2 0 Phage tail sheath C-terminal domain Glycos_trans_3N PF02885.17 CDJ53807.1 - 0.22 11.4 4.4 1.2 9.1 0.9 2.8 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain ATP-cone PF03477.16 CDJ53807.1 - 0.8 10.3 3.4 8.2 7.1 1.3 2.8 2 1 1 3 3 3 0 ATP cone domain TipAS PF07739.13 CDJ53807.1 - 0.83 10.2 6.7 0.56 10.8 0.7 2.9 1 1 1 3 3 3 0 TipAS antibiotic-recognition domain SR-25 PF10500.9 CDJ53808.1 - 0.0005 19.8 9.2 0.00093 18.9 9.2 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 CDJ53808.1 - 0.0032 16.9 2.3 0.0057 16.1 2.2 1.4 1 1 0 1 1 1 1 BUD22 DUF883 PF05957.13 CDJ53808.1 - 0.031 14.9 2.7 0.031 14.9 2.7 3.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Glycos_trans_3N PF02885.17 CDJ53808.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.8 2 1 1 3 3 3 0 Glycosyl transferase family, helical bundle domain Symplekin_C PF12295.8 CDJ53808.1 - 0.16 12.1 0.1 0.44 10.6 0.1 1.8 1 1 0 1 1 1 0 Symplekin tight junction protein C terminal DpnII-MboI PF18742.1 CDJ53808.1 - 0.18 11.4 0.0 9.9 5.8 0.0 2.2 2 0 0 2 2 2 0 REase_DpnII-MboI DUF515 PF04415.12 CDJ53808.1 - 0.19 10.1 3.0 0.27 9.6 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Rrn6 PF10214.9 CDJ53808.1 - 0.26 9.8 5.6 0.42 9.1 5.6 1.4 1 1 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor GREB1 PF15782.5 CDJ53808.1 - 1.2 6.1 4.6 1.5 5.9 4.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RAP1 PF07218.11 CDJ53808.1 - 9 4.4 11.2 12 4.0 11.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UCH PF00443.29 CDJ53809.1 - 1.2e-26 93.8 0.0 1.8e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ53809.1 - 0.072 12.7 0.7 1.8 8.1 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase Spt20 PF12090.8 CDJ53809.1 - 0.23 11.1 4.1 0.22 11.1 0.9 2.0 2 0 0 2 2 2 0 Spt20 family Roughex PF06020.11 CDJ53809.1 - 0.86 8.6 5.7 1.9 7.5 5.7 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 CDJ53809.1 - 1.5 7.5 5.9 7.5 5.2 0.9 2.1 2 0 0 2 2 2 0 Presenilin Fasciclin PF02469.22 CDJ53810.1 - 0.00016 21.9 0.0 0.037 14.3 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain NHL PF01436.21 CDJ53811.1 - 0.044 13.8 0.2 1.3 9.1 0.2 4.0 1 0 0 1 1 1 0 NHL repeat EcoRII-N PF09217.10 CDJ53811.1 - 0.074 12.8 1.8 7.1 6.4 0.1 3.0 3 0 0 3 3 3 0 Restriction endonuclease EcoRII, N-terminal zf-C3HC4 PF00097.25 CDJ53812.1 - 0.078 12.9 0.5 0.16 11.9 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ53812.1 - 0.13 12.1 0.7 0.29 11.0 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LSM PF01423.22 CDJ53813.1 - 6.2e-16 57.8 0.2 9.2e-16 57.3 0.2 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDJ53813.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Hfq protein FA_synthesis PF02504.15 CDJ53813.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 Fatty acid synthesis protein SPC22 PF04573.12 CDJ53814.1 - 5.9e-40 136.5 0.0 7.8e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 Signal peptidase subunit TBCC PF07986.12 CDJ53814.1 - 0.027 14.2 0.0 0.72 9.6 0.0 2.1 2 0 0 2 2 2 0 Tubulin binding cofactor C TSA PF03249.13 CDJ53814.1 - 0.036 12.9 2.0 0.041 12.7 2.0 1.1 1 0 0 1 1 1 0 Type specific antigen RRP14 PF15459.6 CDJ53814.1 - 0.1 13.3 3.9 12 6.6 3.3 2.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Spt20 PF12090.8 CDJ53814.1 - 0.22 11.1 6.0 0.32 10.6 6.0 1.3 1 0 0 1 1 1 0 Spt20 family MscS_TM PF12794.7 CDJ53814.1 - 0.51 9.1 3.6 0.66 8.8 3.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2967 PF11179.8 CDJ53814.1 - 0.54 8.3 7.5 0.67 8.0 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) AAA_28 PF13521.6 CDJ53814.1 - 1 9.6 5.5 11 6.2 2.8 2.1 1 1 1 2 2 2 0 AAA domain Presenilin PF01080.17 CDJ53816.1 - 0.72 8.6 11.6 0.75 8.5 11.6 1.0 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 CDJ53816.1 - 0.85 9.0 7.7 0.99 8.8 7.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pex14_N PF04695.13 CDJ53816.1 - 0.92 10.2 17.0 1 10.0 17.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4407 PF14362.6 CDJ53816.1 - 1.7 8.0 11.9 1.8 7.8 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cellulose_synt PF03552.14 CDJ53816.1 - 2 6.8 3.7 1.8 6.9 3.7 1.1 1 0 0 1 1 1 0 Cellulose synthase V_ATPase_I PF01496.19 CDJ53816.1 - 2 6.2 11.5 2.2 6.1 11.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4449 PF14613.6 CDJ53816.1 - 2.1 8.5 12.6 2.4 8.2 12.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Coilin_N PF15862.5 CDJ53816.1 - 2.7 7.8 14.2 3.7 7.4 14.2 1.3 1 0 0 1 1 1 0 Coilin N-terminus Band_3_cyto PF07565.13 CDJ53816.1 - 2.8 7.7 9.7 2.9 7.6 9.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.12 CDJ53816.1 - 3.5 6.5 14.8 3.4 6.6 14.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ53816.1 - 4.3 7.3 16.7 5.4 7.0 16.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Connexin PF00029.19 CDJ53816.1 - 4.8 6.9 9.6 5.4 6.7 9.6 1.1 1 0 0 1 1 1 0 Connexin Folliculin PF11704.8 CDJ53816.1 - 5 7.0 9.6 6.1 6.7 9.6 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Neur_chan_memb PF02932.16 CDJ53816.1 - 5 7.1 11.1 5 7.1 11.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDM31_MDM32 PF08118.11 CDJ53816.1 - 5.1 5.6 7.7 5.6 5.5 7.7 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Hid1 PF12722.7 CDJ53816.1 - 5.4 5.0 10.1 5 5.1 10.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 CDJ53816.1 - 7.6 6.3 12.4 7.4 6.3 12.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WRW PF10206.9 CDJ53817.1 - 0.041 14.3 0.3 0.073 13.4 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Lin-8 PF03353.15 CDJ53817.1 - 0.9 9.0 22.7 1.3 8.5 22.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ53817.1 - 1.2 8.9 19.1 1.5 8.7 19.1 1.3 1 0 0 1 1 1 0 SPX domain Pkinase_fungal PF17667.1 CDJ53817.1 - 1.4 7.6 9.8 1.6 7.4 9.8 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF572 PF04502.13 CDJ53817.1 - 3.5 7.2 22.7 4 7.0 22.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S64 PF08192.11 CDJ53817.1 - 7.9 4.8 21.7 8.9 4.7 21.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 His_Phos_1 PF00300.22 CDJ53818.1 - 8.9e-06 25.5 8.2 0.078 12.7 0.1 4.0 3 1 1 4 4 4 3 Histidine phosphatase superfamily (branch 1) TFIIA PF03153.13 CDJ53818.1 - 0.83 9.6 14.2 1.4 8.8 14.2 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ53818.1 - 5.1 6.6 11.5 7.8 6.0 11.5 1.2 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ53818.1 - 6.6 5.6 17.0 10 4.9 17.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ53819.1 - 0.33 10.9 11.3 0.44 10.5 11.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK2AP PF09806.9 CDJ53823.1 - 0.016 15.3 13.8 0.016 15.3 13.8 2.3 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF4820 PF16091.5 CDJ53823.1 - 0.13 11.6 8.2 0.2 11.0 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4484 PF14831.6 CDJ53823.1 - 0.59 10.1 9.0 0.74 9.8 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) RIFIN PF02009.16 CDJ53823.1 - 0.98 9.3 9.7 1.3 8.9 9.7 1.1 1 0 0 1 1 1 0 Rifin DUF3959 PF13105.6 CDJ53823.1 - 1.4 8.4 5.3 2.1 7.8 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Presenilin PF01080.17 CDJ53823.1 - 1.6 7.4 8.3 2 7.1 8.3 1.3 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 CDJ53823.1 - 3.3 8.0 42.8 0.028 14.7 29.1 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF755 PF05501.11 CDJ53826.1 - 0.004 17.4 5.0 0.004 17.4 5.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF755) AF-4 PF05110.13 CDJ53826.1 - 6.1 4.8 41.3 0.012 13.7 18.9 2.0 1 1 1 2 2 2 0 AF-4 proto-oncoprotein API5 PF05918.11 CDJ53826.1 - 6.2 5.5 15.3 3.2 6.5 12.7 1.7 1 1 1 2 2 2 0 Apoptosis inhibitory protein 5 (API5) AAA_23 PF13476.6 CDJ53826.1 - 7.4 7.0 12.4 0.047 14.2 2.5 1.9 1 1 1 2 2 2 0 AAA domain DUF3824 PF12868.7 CDJ53826.1 - 9.2 6.9 21.5 1.2 9.8 7.7 2.5 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) PRCC PF10253.9 CDJ53827.1 - 5.9e-08 33.8 15.4 5.9e-08 33.8 15.4 6.7 4 2 0 4 4 4 2 Mitotic checkpoint regulator, MAD2B-interacting DUF1645 PF07816.11 CDJ53827.1 - 0.0018 18.9 0.9 0.0018 18.9 0.9 5.0 5 1 0 5 5 5 2 Protein of unknown function (DUF1645) DUF2722 PF10846.8 CDJ53827.1 - 0.6 9.0 32.4 0.023 13.6 8.8 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) ETRAMP PF09716.10 CDJ53827.1 - 1.4 9.0 0.0 1.4 9.0 0.0 6.4 7 1 0 7 7 7 0 Malarial early transcribed membrane protein (ETRAMP) DUF2722 PF10846.8 CDJ53828.1 - 0.0027 16.7 16.3 0.0027 16.7 16.3 6.3 6 1 0 6 6 6 3 Protein of unknown function (DUF2722) TMEM247 PF15444.6 CDJ53828.1 - 0.0033 17.5 2.3 0.0033 17.5 2.3 4.4 4 0 0 4 4 4 1 Transmembrane protein 247 FlgH PF02107.16 CDJ53829.1 - 0.011 15.3 2.2 0.019 14.6 1.3 1.7 2 0 0 2 2 2 0 Flagellar L-ring protein DUF3446 PF11928.8 CDJ53829.1 - 0.14 12.4 31.4 0.16 12.3 8.2 3.4 3 0 0 3 3 3 0 Early growth response N-terminal domain CDK2AP PF09806.9 CDJ53829.1 - 1.3 9.1 13.5 0.44 10.6 0.2 2.4 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein TFIIA PF03153.13 CDJ53830.1 - 0.0083 16.2 68.0 0.14 12.2 31.7 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF4179 PF13786.6 CDJ53830.1 - 0.12 12.8 1.2 0.25 11.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) CAF1 PF04857.20 CDJ53830.1 - 2 7.5 7.3 6.6 5.8 0.1 2.2 2 0 0 2 2 2 0 CAF1 family ribonuclease SUIM_assoc PF16619.5 CDJ53831.1 - 0.0088 16.1 1.5 0.0088 16.1 1.5 3.5 2 1 1 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 DUF3459 PF11941.8 CDJ53831.1 - 0.91 9.9 7.9 0.25 11.7 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3459) PAT1 PF09770.9 CDJ53831.1 - 1.5 7.0 27.9 1.7 6.8 27.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.19 CDJ53831.1 - 1.9 9.1 53.3 1.8 9.2 4.8 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Elf1 PF05129.13 CDJ53832.1 - 5.6e-25 87.2 0.5 5.6e-25 87.2 0.5 4.3 4 1 0 4 4 4 1 Transcription elongation factor Elf1 like Pkinase PF00069.25 CDJ53833.1 - 1.4e-80 270.5 0.0 2.1e-80 269.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ53833.1 - 6.5e-43 146.9 0.0 2.3e-42 145.1 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ53833.1 - 7.1e-29 97.2 7.9 3.9e-07 29.1 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ53833.1 - 5.8e-25 87.5 5.1 3.8e-12 46.5 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ53833.1 - 6.2e-23 78.7 4.1 2.2e-05 24.0 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ53833.1 - 1.1e-20 72.1 5.4 2.7e-06 26.6 0.2 4.8 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDJ53833.1 - 4.6e-13 48.8 11.5 9.9e-05 22.1 1.4 4.6 4 1 1 5 5 5 4 EF-hand domain pair Kinase-like PF14531.6 CDJ53833.1 - 5.5e-07 29.2 0.0 3.7e-06 26.5 0.0 2.0 1 1 0 2 2 2 1 Kinase-like SPARC_Ca_bdg PF10591.9 CDJ53833.1 - 6.6e-07 29.6 2.7 0.003 17.9 0.4 3.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDJ53833.1 - 1.2e-05 25.2 5.4 0.001 19.0 0.6 3.7 3 1 1 4 4 4 1 Cytoskeletal-regulatory complex EF hand Pkinase_fungal PF17667.1 CDJ53833.1 - 4.9e-05 22.3 0.0 7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_10 PF14788.6 CDJ53833.1 - 0.0036 17.1 1.4 1.4 8.9 0.0 3.5 4 0 0 4 4 4 1 EF hand Kdo PF06293.14 CDJ53833.1 - 0.0046 16.3 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ53833.1 - 0.007 16.3 0.0 0.091 12.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_9 PF14658.6 CDJ53833.1 - 0.065 13.6 0.3 0.43 10.9 0.1 2.4 2 1 0 2 2 2 0 EF-hand domain FHIPEP PF00771.20 CDJ53834.1 - 0.89 7.9 20.2 1 7.7 20.2 1.1 1 0 0 1 1 1 0 FHIPEP family Auxin_canalis PF05703.11 CDJ53834.1 - 1.4 8.8 24.7 1.8 8.5 24.7 1.1 1 0 0 1 1 1 0 Auxin canalisation BSP_II PF05432.11 CDJ53834.1 - 7.1 6.2 20.7 9.2 5.9 20.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) AAR2 PF05282.11 CDJ53835.1 - 0.66 9.3 4.8 0.15 11.4 1.8 1.5 2 0 0 2 2 2 0 AAR2 protein DUF2722 PF10846.8 CDJ53837.1 - 0.005 15.9 9.3 0.0063 15.5 9.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) UPF0560 PF10577.9 CDJ53837.1 - 0.019 13.5 2.5 0.019 13.5 2.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Suf PF05843.14 CDJ53837.1 - 0.056 13.4 3.2 0.054 13.5 3.2 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ53837.1 - 0.13 12.2 15.1 0.16 12.0 15.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ53837.1 - 0.16 11.6 18.6 0.22 11.1 18.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF5349 PF17298.2 CDJ53837.1 - 0.68 9.6 8.3 0.82 9.4 8.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF4834 PF16118.5 CDJ53837.1 - 1.3 10.0 5.2 1.8 9.6 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3682 PF12446.8 CDJ53837.1 - 1.9 9.0 10.2 2.7 8.5 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF3533 PF12051.8 CDJ53837.1 - 2.3 7.0 5.2 2.9 6.7 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Activator_LAG-3 PF11498.8 CDJ53837.1 - 3.3 6.6 21.6 3.6 6.4 21.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Roughex PF06020.11 CDJ53837.1 - 4 6.4 7.9 4.5 6.3 7.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PIEZO PF15917.5 CDJ53838.1 - 0.12 11.8 22.6 0.033 13.7 19.1 1.7 2 0 0 2 2 2 0 Piezo Sporozoite_P67 PF05642.11 CDJ53838.1 - 0.12 10.4 12.1 0.2 9.7 11.8 1.5 1 1 0 1 1 1 0 Sporozoite P67 surface antigen FRQ PF09421.10 CDJ53838.1 - 0.15 10.1 9.5 0.21 9.6 9.5 1.3 1 0 0 1 1 1 0 Frequency clock protein MMR1 PF08505.10 CDJ53838.1 - 0.21 11.8 14.0 0.36 11.1 14.0 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein YfhO PF09586.10 CDJ53838.1 - 0.25 9.6 4.1 0.31 9.2 4.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO V_ATPase_I PF01496.19 CDJ53838.1 - 0.3 9.0 10.0 0.46 8.4 10.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BSP_II PF05432.11 CDJ53838.1 - 0.35 10.5 22.3 0.023 14.4 13.7 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) O-antigen_lig PF13425.6 CDJ53838.1 - 0.53 9.0 6.7 0.78 8.5 6.7 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF1117 PF06547.12 CDJ53838.1 - 0.94 10.1 2.8 3.2 8.3 2.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) SID-1_RNA_chan PF13965.6 CDJ53838.1 - 3.3 6.0 4.6 4.4 5.6 4.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ALMT PF11744.8 CDJ53838.1 - 4.6 5.9 11.9 6.1 5.5 11.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Membralin PF09746.9 CDJ53838.1 - 7.9 5.4 10.1 12 4.8 10.1 1.4 1 0 0 1 1 1 0 Tumour-associated protein DUF1168 PF06658.12 CDJ53840.1 - 0.0041 16.9 6.5 0.0041 16.9 6.5 2.2 2 0 0 2 2 1 1 Protein of unknown function (DUF1168) DDHD PF02862.17 CDJ53840.1 - 0.011 15.9 2.9 0.014 15.6 2.0 1.8 2 0 0 2 2 2 0 DDHD domain SprA-related PF12118.8 CDJ53840.1 - 0.054 12.6 21.0 0.11 11.7 21.0 1.4 1 0 0 1 1 1 0 SprA-related family Presenilin PF01080.17 CDJ53840.1 - 0.14 10.9 9.8 0.17 10.6 9.8 1.2 1 0 0 1 1 1 0 Presenilin Rpp20 PF12328.8 CDJ53840.1 - 0.38 10.7 7.8 0.62 10.0 7.8 1.3 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P CPSF100_C PF13299.6 CDJ53840.1 - 0.52 10.5 6.0 1 9.5 6.0 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Gti1_Pac2 PF09729.9 CDJ53840.1 - 0.64 10.1 7.9 1.2 9.2 7.9 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family RR_TM4-6 PF06459.12 CDJ53840.1 - 0.74 9.6 9.8 1.5 8.6 9.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cellulose_synt PF03552.14 CDJ53840.1 - 1.1 7.6 2.9 1.5 7.2 2.9 1.0 1 0 0 1 1 1 0 Cellulose synthase EOS1 PF12326.8 CDJ53840.1 - 1.6 8.6 5.4 1.5 8.7 5.4 1.3 1 1 0 1 1 1 0 N-glycosylation protein FYDLN_acid PF09538.10 CDJ53840.1 - 2 9.1 9.0 4.4 8.0 9.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Suf PF05843.14 CDJ53840.1 - 3.3 7.6 16.7 0.42 10.6 12.5 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 CDJ53840.1 - 3.9 6.4 17.5 5.4 5.9 17.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CTU2 PF10288.9 CDJ53840.1 - 4.7 7.5 15.9 11 6.4 15.9 1.5 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 TrmE_N PF10396.9 CDJ53842.1 - 1.2e-20 74.0 0.0 4e-14 52.9 0.0 3.3 2 0 0 2 2 2 2 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 CDJ53842.1 - 1.9e-15 56.9 0.0 4.7e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RskA PF10099.9 CDJ53842.1 - 0.0001 22.6 17.5 0.0028 18.0 0.3 8.7 5 2 1 7 7 7 3 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ53842.1 - 0.00022 20.3 5.4 0.00022 20.3 5.4 5.5 4 1 1 5 5 5 1 Protein of unknown function (DUF2722) Dynamin_N PF00350.23 CDJ53842.1 - 0.0023 18.0 0.0 0.0023 18.0 0.0 3.4 2 1 0 2 2 2 1 Dynamin family DDHD PF02862.17 CDJ53842.1 - 0.008 16.4 4.3 0.008 16.4 4.3 4.3 3 2 0 3 3 3 1 DDHD domain FeoB_N PF02421.18 CDJ53842.1 - 0.035 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Pkinase PF00069.25 CDJ53843.1 - 8.2e-06 25.4 9.9 0.0012 18.2 0.0 4.5 4 2 1 5 5 5 2 Protein kinase domain DUF2722 PF10846.8 CDJ53843.1 - 0.0017 17.4 9.9 0.0017 17.4 9.9 7.3 5 2 1 6 6 6 1 Protein of unknown function (DUF2722) Pkinase_Tyr PF07714.17 CDJ53843.1 - 0.0055 16.0 0.0 0.0055 16.0 0.0 3.9 5 0 0 5 5 5 1 Protein tyrosine kinase PRIMA1 PF16101.5 CDJ53843.1 - 0.0059 16.6 2.2 0.04 14.0 2.2 2.5 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Cyt_bd_oxida_II PF02322.15 CDJ53843.1 - 0.15 11.4 8.2 11 5.2 5.2 3.2 3 0 0 3 3 3 0 Cytochrome bd terminal oxidase subunit II PIP5K PF01504.18 CDJ53843.1 - 2.1 7.5 32.2 0.021 14.1 5.0 4.0 4 0 0 4 4 4 0 Phosphatidylinositol-4-phosphate 5-Kinase Connexin PF00029.19 CDJ53843.1 - 7.1 6.3 28.5 5.7 6.6 1.6 4.4 4 0 0 4 4 4 0 Connexin TFIIA PF03153.13 CDJ53844.1 - 0.25 11.3 24.9 0.33 10.9 24.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rrn6 PF10214.9 CDJ53844.1 - 1.4 7.3 17.3 2.1 6.8 17.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4366 PF14283.6 CDJ53844.1 - 2.3 8.2 12.7 4 7.5 0.6 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4366) MCU PF04678.13 CDJ53845.1 - 3.3 7.8 8.2 4 7.5 0.9 2.5 2 0 0 2 2 2 0 Mitochondrial calcium uniporter RAP1 PF07218.11 CDJ53845.1 - 4.1 5.6 7.1 5 5.3 7.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2391 PF09622.10 CDJ53845.1 - 7.7 5.8 8.5 0.51 9.6 0.4 2.6 2 0 0 2 2 2 0 Putative integral membrane protein (DUF2391) Rb_C PF08934.10 CDJ53847.1 - 2.2 8.1 8.6 4.8 7.0 0.7 2.3 1 1 1 2 2 2 0 Rb C-terminal domain Mdv1 PF11542.8 CDJ53847.1 - 8.3 6.5 9.5 3 7.9 1.3 2.5 1 1 1 2 2 2 0 Mitochondrial division protein 1 TFIIA PF03153.13 CDJ53848.1 - 0.0036 17.4 4.4 0.0036 17.4 4.4 2.8 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ53848.1 - 0.017 15.2 9.2 0.017 15.2 9.2 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Csm1_N PF18504.1 CDJ53848.1 - 0.82 10.0 8.6 2 8.8 8.6 1.7 1 0 0 1 1 1 0 Csm1 N-terminal domain MRPL52 PF18699.1 CDJ53848.1 - 1.1 9.5 6.0 2.4 8.4 6.0 1.6 1 0 0 1 1 1 0 Mitoribosomal protein mL52 DUF3972 PF13118.6 CDJ53848.1 - 1.6 9.2 5.1 0.46 10.9 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) zf-NADH-PPase PF09297.11 CDJ53848.1 - 1.6 8.5 5.4 0.81 9.4 0.1 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Use1 PF09753.9 CDJ53848.1 - 2 8.1 11.8 1.7 8.3 10.0 1.7 2 0 0 2 2 2 0 Membrane fusion protein Use1 Spt20 PF12090.8 CDJ53848.1 - 6.1 6.4 15.1 0.16 11.6 8.1 1.9 2 0 0 2 2 2 0 Spt20 family RNA_GG_bind PF10258.9 CDJ53849.1 - 1.5e-25 89.0 0.1 2.7e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 PHAX RNA-binding domain YjgF_endoribonc PF14588.6 CDJ53850.1 - 0.023 14.8 0.2 0.062 13.4 0.0 1.8 2 0 0 2 2 2 0 YjgF/chorismate_mutase-like, putative endoribonuclease CPP1-like PF11833.8 CDJ53850.1 - 0.078 12.6 0.3 0.078 12.6 0.3 1.9 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF1700 PF08006.11 CDJ53851.1 - 1.3 8.6 7.2 0.31 10.5 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) SNF2_N PF00176.23 CDJ53852.1 - 1.6e-56 191.5 0.0 2.2e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ53852.1 - 1.1e-12 48.3 0.0 2.8e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ53852.1 - 1.8e-09 37.8 0.0 3.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ53852.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 CDJ53852.1 - 0.0025 17.1 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 CDJ53852.1 - 0.037 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase MA3 PF02847.17 CDJ53853.1 - 0.00096 19.1 0.1 0.0024 17.8 0.1 1.7 1 0 0 1 1 1 1 MA3 domain CDC27 PF09507.10 CDJ53853.1 - 0.083 12.3 1.8 0.16 11.3 1.8 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Vps51 PF08700.11 CDJ53854.1 - 0.0033 17.5 0.0 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 Glyco_transf_4 PF13439.6 CDJ53856.1 - 0.016 15.2 0.0 0.12 12.4 0.0 2.0 1 1 1 2 2 2 0 Glycosyltransferase Family 4 tRNA-synt_2b PF00587.25 CDJ53857.1 - 1.4e-25 90.4 0.0 3.9e-25 88.9 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Kinesin PF00225.23 CDJ53858.1 - 4.4e-80 269.1 0.3 9.5e-78 261.4 0.3 2.4 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ53858.1 - 3.8e-20 72.3 0.3 1.9e-16 60.3 0.0 3.5 3 0 0 3 3 3 2 Microtubule binding AAA_22 PF13401.6 CDJ53858.1 - 0.14 12.4 0.2 5.1 7.4 0.0 3.2 4 0 0 4 4 4 0 AAA domain bZIP_2 PF07716.15 CDJ53858.1 - 9.2 6.4 10.9 16 5.6 0.4 4.4 3 0 0 3 3 3 0 Basic region leucine zipper Pkinase PF00069.25 CDJ53859.1 - 1.1e-05 25.0 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ53859.1 - 0.006 15.9 0.0 0.015 14.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ53859.1 - 0.036 13.3 0.0 0.078 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase HATPase_c PF02518.26 CDJ53860.1 - 1.4e-08 35.2 0.3 4.7e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ53860.1 - 2.4e-07 30.6 0.0 4.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase X PF00739.19 CDJ53860.1 - 0.003 17.7 2.3 0.0054 16.9 2.3 1.4 1 0 0 1 1 1 1 Trans-activation protein X SPX PF03105.19 CDJ53860.1 - 2.9 7.7 13.4 4 7.3 13.4 1.1 1 0 0 1 1 1 0 SPX domain DNA_mis_repair PF01119.19 CDJ53861.1 - 7.5e-13 48.2 0.0 1.6e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain SR-25 PF10500.9 CDJ53861.1 - 2.5e-06 27.3 12.6 2.5e-06 27.3 12.6 6.7 5 1 0 6 6 6 3 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ53861.1 - 0.0056 17.0 8.6 0.0056 17.0 8.6 9.7 3 2 1 4 4 4 1 Anti-sigma-K factor rskA Pex14_N PF04695.13 CDJ53861.1 - 0.017 15.8 4.4 0.017 15.8 4.4 10.1 5 3 2 7 7 7 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Activator_LAG-3 PF11498.8 CDJ53862.1 - 0.00012 21.2 17.0 0.00012 21.2 17.0 1.5 2 0 0 2 2 2 1 Transcriptional activator LAG-3 NAM-associated PF14303.6 CDJ53862.1 - 0.084 13.6 8.8 0.15 12.8 7.3 2.0 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain TFIIA PF03153.13 CDJ53862.1 - 3.1 7.7 25.4 4 7.3 25.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNase_HII PF01351.18 CDJ53863.1 - 6.8e-24 84.8 5.0 4.3e-20 72.4 1.1 2.6 1 1 1 2 2 2 2 Ribonuclease HII CTU2 PF10288.9 CDJ53863.1 - 0.14 12.4 3.0 0.31 11.3 3.0 1.5 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 TFIIA PF03153.13 CDJ53863.1 - 0.44 10.5 10.2 0.55 10.2 10.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ53863.1 - 0.49 10.0 7.9 0.63 9.6 7.9 1.2 1 0 0 1 1 1 0 Spt20 family E_Pc_C PF06752.12 CDJ53863.1 - 2.2 8.4 12.7 1.9 8.5 8.5 2.1 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Aminotran_4 PF01063.19 CDJ53864.1 - 4.5e-12 46.3 2.5 4.8e-12 46.2 0.0 2.5 2 1 1 3 3 3 1 Amino-transferase class IV DUF1645 PF07816.11 CDJ53864.1 - 0.00041 21.0 10.3 0.00041 21.0 10.3 5.2 4 2 0 4 4 4 1 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ53864.1 - 0.0017 18.0 16.4 0.0017 18.0 16.4 4.5 4 1 0 4 4 4 1 Nuclear RNA-splicing-associated protein BORG_CEP PF14957.6 CDJ53864.1 - 0.023 15.9 4.5 0.023 15.9 4.5 4.8 4 1 0 4 4 4 0 Cdc42 effector PRP1_N PF06424.12 CDJ53864.1 - 3.4 8.1 52.6 1.1 9.7 2.9 4.3 4 0 0 4 4 4 0 PRP1 splicing factor, N-terminal Hamartin PF04388.12 CDJ53864.1 - 8.4 4.9 61.5 0.04 12.6 3.7 3.1 3 0 0 3 3 3 0 Hamartin protein SPX PF03105.19 CDJ53865.1 - 0.0057 16.6 11.8 0.0057 16.6 11.8 3.7 2 1 0 3 3 3 1 SPX domain RskA PF10099.9 CDJ53866.1 - 5.5e-05 23.5 64.5 0.013 15.8 3.0 5.6 2 2 2 4 4 4 3 Anti-sigma-K factor rskA SPX PF03105.19 CDJ53866.1 - 0.00053 20.0 43.4 0.0009 19.3 19.9 3.2 3 0 0 3 3 3 3 SPX domain Caa3_CtaG PF09678.10 CDJ53866.1 - 0.04 13.4 1.3 0.17 11.3 0.9 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF4179 PF13786.6 CDJ53866.1 - 0.21 12.1 11.6 17 6.0 0.0 4.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4179) Cloacin PF03515.14 CDJ53866.1 - 0.29 10.8 10.5 0.47 10.1 3.0 2.7 2 0 0 2 2 2 0 Colicin-like bacteriocin tRNase domain DUF4131 PF13567.6 CDJ53866.1 - 0.71 9.5 10.7 1.3 8.6 0.4 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF4834 PF16118.5 CDJ53866.1 - 1.8 9.5 44.9 1.2 10.1 4.2 5.9 6 0 0 6 6 6 0 Domain of unknown function (DUF4834) Filament_head PF04732.14 CDJ53867.1 - 4.3 8.3 48.0 0.87 10.5 5.5 4.6 4 0 0 4 4 4 0 Intermediate filament head (DNA binding) region Stk19 PF10494.9 CDJ53868.1 - 3e-05 23.8 1.8 3e-05 23.8 1.8 2.5 3 1 0 3 3 3 1 Serine-threonine protein kinase 19 SPX PF03105.19 CDJ53868.1 - 0.00024 21.2 18.2 0.00024 21.2 18.2 2.4 2 0 0 2 2 2 2 SPX domain RskA PF10099.9 CDJ53869.1 - 4.8e-06 27.0 0.3 4.8e-06 27.0 0.3 9.7 3 2 2 5 5 5 2 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ53869.1 - 0.0059 16.7 37.8 0.0059 16.7 37.8 6.0 2 1 2 5 5 5 1 Transcription factor IIA, alpha/beta subunit ACR_tran PF00873.19 CDJ53871.1 - 0.011 13.4 7.8 0.011 13.4 7.8 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Piezo_RRas_bdg PF12166.8 CDJ53871.1 - 0.024 13.9 6.2 0.035 13.4 6.2 1.2 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Pannexin_like PF12534.8 CDJ53871.1 - 0.026 13.6 5.5 0.032 13.3 5.5 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 NPR3 PF03666.13 CDJ53871.1 - 0.028 13.2 9.9 0.029 13.2 9.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SID-1_RNA_chan PF13965.6 CDJ53871.1 - 0.043 12.2 3.8 0.05 12.0 3.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CDJ53871.1 - 0.045 13.8 8.6 0.052 13.6 8.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ53871.1 - 0.054 12.2 18.8 0.059 12.1 18.8 1.0 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 CDJ53871.1 - 0.055 12.4 10.3 0.051 12.5 10.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Serinc PF03348.15 CDJ53871.1 - 0.16 10.8 5.0 0.18 10.7 5.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) K_trans PF02705.16 CDJ53871.1 - 0.22 10.0 0.2 0.32 9.4 0.2 1.4 1 1 0 1 1 1 0 K+ potassium transporter Membralin PF09746.9 CDJ53871.1 - 0.33 9.9 6.7 0.34 9.9 6.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4746 PF15928.5 CDJ53871.1 - 1.8 7.9 16.6 2.3 7.6 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) HCO3_cotransp PF00955.21 CDJ53871.1 - 2.2 7.0 3.2 2.3 7.0 3.2 1.1 1 0 0 1 1 1 0 HCO3- transporter family RR_TM4-6 PF06459.12 CDJ53871.1 - 4.6 7.0 21.5 5.5 6.7 21.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UPF0560 PF10577.9 CDJ53871.1 - 5.9 5.3 24.8 7.3 5.0 24.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIA PF03153.13 CDJ53871.1 - 7.4 6.5 44.5 8.2 6.3 44.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Surface_antigen PF11054.8 CDJ53872.1 - 1.2e-19 71.0 0.7 1.2e-09 38.3 0.0 2.9 2 1 0 2 2 2 2 Sporozoite TA4 surface antigen Secretin_N_2 PF07655.13 CDJ53872.1 - 0.87 10.2 10.2 2.7 8.6 10.2 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain cNMP_binding PF00027.29 CDJ53873.1 - 1e-08 35.1 0.2 3.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain TFIIA PF03153.13 CDJ53873.1 - 6.4e-06 26.4 43.6 6.4e-06 26.4 43.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ53873.1 - 5.3e-05 22.2 25.0 5.7e-05 22.1 25.0 1.2 1 0 0 1 1 1 1 Presenilin Nha1_C PF08619.10 CDJ53873.1 - 0.00088 18.6 23.7 0.00096 18.5 23.7 1.2 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus NARP1 PF12569.8 CDJ53873.1 - 0.0011 18.0 20.7 0.0015 17.5 20.7 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 eIF-3_zeta PF05091.12 CDJ53873.1 - 0.011 14.8 25.1 0.015 14.3 25.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.15 CDJ53873.1 - 0.012 15.2 24.6 0.013 15.1 24.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4045 PF13254.6 CDJ53873.1 - 0.014 15.1 22.1 0.015 14.9 22.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SMYLE_N PF18615.1 CDJ53873.1 - 0.027 14.0 16.4 0.038 13.5 16.4 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Zip PF02535.22 CDJ53873.1 - 0.032 13.5 14.0 0.037 13.3 14.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.13 CDJ53873.1 - 0.038 13.0 23.3 0.041 13.0 23.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF908 PF06012.12 CDJ53873.1 - 0.039 13.4 20.2 0.05 13.0 20.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) CDC45 PF02724.14 CDJ53873.1 - 0.053 11.8 22.9 0.054 11.8 22.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase_fungal PF17667.1 CDJ53873.1 - 0.065 12.0 11.5 0.087 11.6 11.5 1.2 1 0 0 1 1 1 0 Fungal protein kinase Endostatin PF06482.11 CDJ53873.1 - 0.099 12.1 21.2 0.12 11.8 21.2 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin IER PF05760.12 CDJ53873.1 - 0.1 12.9 22.7 0.13 12.6 22.7 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) PAT1 PF09770.9 CDJ53873.1 - 0.11 10.7 38.9 0.12 10.6 38.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neuregulin PF02158.15 CDJ53873.1 - 0.15 11.4 17.3 0.17 11.2 17.3 1.1 1 0 0 1 1 1 0 Neuregulin intracellular region Raftlin PF15250.6 CDJ53873.1 - 0.15 10.8 20.5 0.19 10.5 20.5 1.1 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 CDJ53873.1 - 0.25 10.3 26.4 0.32 10.0 26.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 MCM_bind PF09739.9 CDJ53873.1 - 0.26 9.7 22.0 0.37 9.2 22.0 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor MMR1 PF08505.10 CDJ53873.1 - 0.27 11.5 28.2 0.42 10.8 28.2 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GREB1 PF15782.5 CDJ53873.1 - 0.31 8.1 23.1 0.34 8.0 23.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Med19 PF10278.9 CDJ53873.1 - 0.38 10.7 22.6 0.65 9.9 22.6 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Velvet PF11754.8 CDJ53873.1 - 0.4 10.6 20.1 0.64 9.9 20.1 1.4 1 0 0 1 1 1 0 Velvet factor V_ATPase_I PF01496.19 CDJ53873.1 - 0.42 8.5 26.1 0.54 8.1 26.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Membralin PF09746.9 CDJ53873.1 - 0.42 9.6 15.2 0.51 9.3 15.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein MDM10 PF12519.8 CDJ53873.1 - 0.45 9.3 21.1 0.52 9.1 21.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SARAF PF06682.12 CDJ53873.1 - 0.47 10.1 19.6 0.69 9.5 19.6 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Peptidase_S64 PF08192.11 CDJ53873.1 - 0.53 8.7 18.3 0.6 8.5 18.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 ALMT PF11744.8 CDJ53873.1 - 0.64 8.8 21.9 0.85 8.4 21.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ndc1_Nup PF09531.10 CDJ53873.1 - 0.66 8.6 19.8 0.74 8.4 19.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dapper PF15268.6 CDJ53873.1 - 0.68 8.7 29.2 0.67 8.8 29.2 1.0 1 0 0 1 1 1 0 Dapper Neur_chan_memb PF02932.16 CDJ53873.1 - 1.7 8.6 22.9 2.5 8.1 22.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Otopetrin PF03189.13 CDJ53873.1 - 1.7 7.3 9.7 2.2 7.0 9.7 1.4 1 0 0 1 1 1 0 Otopetrin Hid1 PF12722.7 CDJ53873.1 - 1.8 6.6 28.5 2.2 6.3 28.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 CDJ53873.1 - 2.2 8.0 36.4 0.086 12.7 30.7 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 CDJ53873.1 - 2.7 6.7 30.5 3.6 6.3 30.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.15 CDJ53873.1 - 2.9 6.5 24.4 3.8 6.2 24.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Exonuc_VII_L PF02601.15 CDJ53873.1 - 3.3 7.2 23.0 3.5 7.1 23.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2370 PF10176.9 CDJ53873.1 - 4 7.0 13.6 5.9 6.5 13.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) PA26 PF04636.13 CDJ53873.1 - 4.8 6.0 21.0 6.4 5.6 21.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) VIR_N PF15912.5 CDJ53873.1 - 5.5 6.5 20.0 7.6 6.0 20.0 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal SPATA3 PF15662.5 CDJ53873.1 - 5.9 7.5 19.0 8.4 7.0 19.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DUF4175 PF13779.6 CDJ53873.1 - 7.7 4.3 54.9 12 3.6 54.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) F-protein PF00469.20 CDJ53873.1 - 8.8 5.9 24.8 15 5.1 24.8 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef XRN_M PF17846.1 CDJ53873.1 - 10 5.0 25.9 14 4.5 25.9 1.2 1 0 0 1 1 1 0 Xrn1 helical domain RskA PF10099.9 CDJ53874.1 - 0.00019 21.8 45.3 0.009 16.3 7.6 3.1 2 1 1 3 3 3 3 Anti-sigma-K factor rskA K_channel_TID PF07941.11 CDJ53874.1 - 0.026 15.0 14.0 0.026 15.0 14.0 5.4 4 2 0 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain Utp14 PF04615.13 CDJ53874.1 - 1.2 7.6 43.3 1.8 7.0 43.3 1.1 1 0 0 1 1 1 0 Utp14 protein Ribosomal_60s PF00428.19 CDJ53874.1 - 1.3 9.6 17.7 1.2 9.7 4.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein AF-4 PF05110.13 CDJ53874.1 - 1.7 6.6 50.3 0.72 7.9 38.5 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Dala_Dala_lig_N PF01820.21 CDJ53874.1 - 4.3 7.8 14.5 1.3e+03 -0.1 14.5 3.2 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF4207 PF13904.6 CDJ53874.1 - 7.2 6.2 64.8 0.14 11.9 14.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) RAP1 PF07218.11 CDJ53874.1 - 8 4.6 9.1 10 4.2 9.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_C1 PF00112.23 CDJ53875.1 - 2.2e-30 106.4 29.2 5.9e-15 55.9 5.4 2.2 1 1 1 2 2 2 2 Papain family cysteine protease RskA PF10099.9 CDJ53875.1 - 0.001 19.4 30.3 0.026 14.8 0.1 3.2 3 0 0 3 3 3 2 Anti-sigma-K factor rskA FAM60A PF15396.6 CDJ53875.1 - 0.029 14.4 23.1 0.044 13.8 11.4 2.1 2 0 0 2 2 2 0 Protein Family FAM60A BRF1 PF07741.13 CDJ53875.1 - 0.043 14.1 1.2 0.043 14.1 1.2 3.8 4 0 0 4 4 4 0 Brf1-like TBP-binding domain SARAF PF06682.12 CDJ53875.1 - 0.048 13.3 31.8 0.038 13.6 17.7 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Presenilin PF01080.17 CDJ53875.1 - 0.2 10.4 35.8 0.57 8.9 22.6 2.1 2 0 0 2 2 2 0 Presenilin DUF2052 PF09747.9 CDJ53875.1 - 0.31 11.1 31.8 0.55 10.3 19.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Tudor_FRX1 PF18336.1 CDJ53875.1 - 0.63 10.0 2.5 2 8.4 2.5 1.9 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain DUF2371 PF10177.9 CDJ53875.1 - 0.7 10.1 10.6 5.2 7.2 0.2 3.2 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) Endostatin PF06482.11 CDJ53875.1 - 1.1 8.7 24.9 3.4 7.0 1.2 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Orf78 PF06024.12 CDJ53875.1 - 1.3 9.4 0.0 1.3 9.4 0.0 3.7 4 0 0 4 4 4 0 Orf78 (ac78) DUF2464 PF10240.9 CDJ53875.1 - 1.7 8.1 16.7 0.57 9.7 10.0 2.2 2 0 0 2 2 2 0 Multivesicular body subunit 12 RskA PF10099.9 CDJ53876.1 - 2.8e-05 24.5 4.2 2.8e-05 24.5 4.2 3.4 1 1 1 2 2 2 1 Anti-sigma-K factor rskA FAM176 PF14851.6 CDJ53877.1 - 0.3 10.8 0.0 0.3 10.8 0.0 5.5 4 2 2 6 6 6 0 FAM176 family Pkinase PF00069.25 CDJ53878.1 - 0.00077 18.9 0.0 0.00077 18.9 0.0 2.6 2 0 0 2 2 2 1 Protein kinase domain Dehydrin PF00257.19 CDJ53878.1 - 0.0008 20.0 5.7 0.0008 20.0 5.7 7.5 6 1 1 7 7 7 2 Dehydrin DUF2722 PF10846.8 CDJ53878.1 - 0.0021 17.1 0.0 0.0021 17.1 0.0 8.0 3 1 4 7 7 7 3 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ53879.1 - 0.1 12.7 0.0 0.1 12.7 0.0 4.7 2 2 2 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 CDJ53879.1 - 3.4 8.7 17.8 0.38 11.7 5.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Methyltr_RsmB-F PF01189.17 CDJ53880.1 - 5.5e-11 42.5 0.0 5.5e-11 42.5 0.0 2.8 3 0 0 3 3 3 1 16S rRNA methyltransferase RsmB/F Shadoo PF14999.6 CDJ53880.1 - 0.0087 16.2 0.8 0.0087 16.2 0.8 4.2 3 1 1 4 4 4 1 Shadow of prion protein, neuroprotective Nucleoside_tran PF01733.18 CDJ53881.1 - 2.5e-11 43.5 1.0 2.5e-11 43.5 1.0 2.2 1 1 1 2 2 2 1 Nucleoside transporter DUF1631 PF07793.11 CDJ53881.1 - 1.5e-08 33.6 3.6 1.5e-08 33.6 3.6 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1631) UPF0565 PF10561.9 CDJ53881.1 - 0.00022 20.5 11.2 0.00073 18.8 4.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family UPF0565 BAF1_ABF1 PF04684.13 CDJ53881.1 - 0.078 12.0 36.1 0.051 12.6 22.3 2.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor O-antigen_lig PF13425.6 CDJ53881.1 - 2.6 6.7 5.5 3.8 6.2 5.5 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Exonuc_VII_L PF02601.15 CDJ53881.1 - 3.7 7.0 31.4 0.7 9.4 23.0 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit RIFIN PF02009.16 CDJ53881.1 - 8.2 6.2 26.6 0.087 12.7 8.7 2.6 3 0 0 3 3 3 0 Rifin PAT1 PF09770.9 CDJ53882.1 - 0.25 9.6 48.7 0.33 9.2 48.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC27 PF09507.10 CDJ53882.1 - 4.6 6.5 26.2 7.4 5.8 26.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 V_ATPase_I PF01496.19 CDJ53883.1 - 0.0022 16.0 7.3 0.0022 16.0 7.3 3.0 2 1 1 3 3 3 1 V-type ATPase 116kDa subunit family SR-25 PF10500.9 CDJ53883.1 - 0.0095 15.6 22.3 0.0095 15.6 22.3 2.6 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ53884.1 - 3.6e-05 23.5 17.1 4.8e-05 23.1 17.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 CDJ53884.1 - 0.0028 17.5 14.9 0.0037 17.2 14.9 1.3 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Utp14 PF04615.13 CDJ53884.1 - 0.063 11.9 22.1 0.073 11.6 22.1 1.1 1 0 0 1 1 1 0 Utp14 protein PAT1 PF09770.9 CDJ53884.1 - 0.066 11.5 23.0 0.066 11.5 23.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ53884.1 - 0.13 12.3 10.0 0.16 12.0 10.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spc7_N PF15402.6 CDJ53884.1 - 0.24 9.6 25.5 0.39 8.9 25.5 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Peroxin-3 PF04882.12 CDJ53884.1 - 0.3 10.0 16.8 0.32 9.9 16.8 1.3 1 0 0 1 1 1 0 Peroxin-3 TFIIA PF03153.13 CDJ53884.1 - 0.31 11.0 47.2 0.47 10.4 47.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF913 PF06025.12 CDJ53884.1 - 0.32 9.9 10.0 0.35 9.8 10.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.6 CDJ53884.1 - 0.41 9.0 2.8 0.39 9.1 2.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 STAC2_u1 PF16664.5 CDJ53884.1 - 0.76 10.2 21.8 1.5 9.3 21.8 1.5 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 eIF-3_zeta PF05091.12 CDJ53884.1 - 0.84 8.5 23.1 0.93 8.4 23.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) LAP1C PF05609.12 CDJ53884.1 - 1.2 8.2 20.2 1.3 8.0 20.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 CDJ53884.1 - 1.2 7.8 26.2 1.6 7.4 26.2 1.2 1 0 0 1 1 1 0 Presenilin SelP_N PF04592.14 CDJ53884.1 - 1.2 8.5 17.5 1.6 8.1 17.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SLC12 PF03522.15 CDJ53884.1 - 1.9 7.4 16.9 2.2 7.2 16.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 CDJ53884.1 - 4 5.8 17.2 4.6 5.6 17.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4106 PF13388.6 CDJ53884.1 - 4.4 6.4 24.3 5 6.2 24.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RskA PF10099.9 CDJ53884.1 - 4.4 7.6 44.0 0.013 15.8 21.4 3.0 1 1 1 2 2 1 0 Anti-sigma-K factor rskA Hid1 PF12722.7 CDJ53884.1 - 5.1 5.1 20.2 5.9 4.9 20.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dicty_REP PF05086.12 CDJ53884.1 - 5.1 4.9 12.4 6.1 4.7 12.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GREB1 PF15782.5 CDJ53884.1 - 5.7 3.9 20.0 6.3 3.8 20.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PsaL PF02605.15 CDJ53887.1 - 3.2e-05 23.6 0.7 0.061 13.0 0.1 2.9 2 1 0 2 2 2 2 Photosystem I reaction centre subunit XI DUF2722 PF10846.8 CDJ53887.1 - 0.002 17.1 16.4 0.002 17.1 16.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ53887.1 - 0.0023 18.9 2.5 0.0071 17.3 2.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Ctr PF04145.15 CDJ53887.1 - 0.0031 18.1 0.6 0.0031 18.1 0.6 2.0 2 0 0 2 2 2 1 Ctr copper transporter family eIF-3_zeta PF05091.12 CDJ53887.1 - 0.021 13.8 2.3 0.036 13.1 2.3 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RskA PF10099.9 CDJ53887.1 - 0.03 14.6 1.0 0.03 14.6 1.0 4.2 1 1 2 4 4 4 0 Anti-sigma-K factor rskA DUF898 PF05987.13 CDJ53887.1 - 0.039 13.0 2.0 0.073 12.1 2.0 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Cohesin_HEAT PF12765.7 CDJ53887.1 - 0.078 13.3 0.0 0.85 10.0 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion FAM176 PF14851.6 CDJ53887.1 - 0.082 12.6 0.8 0.16 11.7 0.8 1.4 1 0 0 1 1 1 0 FAM176 family DUF4770 PF15994.5 CDJ53887.1 - 0.15 12.3 6.5 0.26 11.5 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Sulf_transp PF04143.14 CDJ53887.1 - 0.2 11.2 9.0 0.22 11.1 1.1 3.3 2 1 1 3 3 3 0 Sulphur transport DUF1645 PF07816.11 CDJ53887.1 - 0.29 11.7 15.1 0.34 11.5 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) TMEM51 PF15345.6 CDJ53887.1 - 0.46 10.3 7.7 1.1 9.0 7.7 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 UPF0560 PF10577.9 CDJ53887.1 - 0.78 8.2 13.7 1.3 7.4 13.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TERB2 PF15101.6 CDJ53887.1 - 0.93 9.5 8.7 1.8 8.5 8.7 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EIIBC-GUT_N PF03612.14 CDJ53887.1 - 1.1 9.0 3.5 2 8.1 3.5 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TFIIA PF03153.13 CDJ53887.1 - 1.9 8.4 41.8 0.064 13.2 18.8 2.6 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ53887.1 - 2.1 8.3 12.2 2.2 8.2 9.2 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4667 PF15700.5 CDJ53887.1 - 4.1 7.4 19.4 4.8 7.2 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) BORG_CEP PF14957.6 CDJ53887.1 - 6.1 8.0 11.7 3.9 8.7 6.0 2.4 2 0 0 2 2 2 0 Cdc42 effector HHH_9 PF17674.1 CDJ53887.1 - 9.7 7.2 8.2 7.1 7.6 0.0 3.0 3 0 0 3 3 2 0 HHH domain TFIIA PF03153.13 CDJ53889.1 - 0.00094 19.3 30.0 0.0013 18.8 30.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1645 PF07816.11 CDJ53889.1 - 0.47 11.0 15.9 0.57 10.7 8.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) CagX PF03524.15 CDJ53889.1 - 5.7 6.6 7.6 2.6 7.7 0.8 2.2 2 0 0 2 2 2 0 Conjugal transfer protein Radical_SAM PF04055.21 CDJ53890.1 - 3.3e-05 24.3 0.0 0.0019 18.6 0.0 2.1 1 1 0 2 2 2 1 Radical SAM superfamily TAF4 PF05236.14 CDJ53890.1 - 0.00042 20.1 9.6 0.0006 19.6 9.6 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family AF-4 PF05110.13 CDJ53890.1 - 0.029 12.5 18.8 0.046 11.8 18.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NST1 PF13945.6 CDJ53890.1 - 0.043 13.9 13.3 0.072 13.2 13.3 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF572 PF04502.13 CDJ53890.1 - 0.069 12.8 9.4 0.094 12.3 9.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) GREB1 PF15782.5 CDJ53890.1 - 0.088 9.9 12.4 0.1 9.7 12.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CDJ53890.1 - 0.091 11.0 22.4 0.11 10.7 22.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 CDJ53890.1 - 0.1 12.1 16.4 0.18 11.3 16.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MAT1 PF06391.13 CDJ53890.1 - 0.23 11.3 15.8 0.43 10.4 15.8 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 LTV PF04180.14 CDJ53890.1 - 0.23 11.1 10.4 0.36 10.5 10.4 1.2 1 0 0 1 1 1 0 Low temperature viability protein Baculo_PP31 PF05311.11 CDJ53890.1 - 0.25 10.8 6.2 0.41 10.1 6.2 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Zip PF02535.22 CDJ53890.1 - 0.49 9.6 2.5 0.77 8.9 2.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.13 CDJ53890.1 - 0.5 9.4 10.1 0.72 8.8 10.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor LCD1 PF09798.9 CDJ53890.1 - 0.95 7.9 14.7 1.2 7.5 14.7 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein PAP1 PF08601.10 CDJ53890.1 - 1.1 8.9 17.1 1.6 8.4 17.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 RskA PF10099.9 CDJ53890.1 - 1.6 9.0 29.3 0.065 13.5 13.4 2.6 1 1 1 2 2 2 0 Anti-sigma-K factor rskA IMUP PF15761.5 CDJ53890.1 - 2.8 8.7 17.4 0.69 10.6 13.7 1.9 1 1 1 2 2 2 0 Immortalisation up-regulated protein Asp-B-Hydro_N PF05279.11 CDJ53890.1 - 6.5 6.7 10.5 12 5.9 10.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region VIT1 PF01988.19 CDJ53890.1 - 6.6 6.5 10.8 4 7.2 8.7 1.6 2 0 0 2 2 2 0 VIT family Presenilin PF01080.17 CDJ53890.1 - 8 5.1 15.0 13 4.4 15.0 1.4 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CDJ53890.1 - 9.3 4.2 13.1 12 3.9 13.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Trp_oprn_chp PF09534.10 CDJ53890.1 - 9.5 6.0 12.0 36 4.1 12.0 1.9 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sec62 PF03839.16 CDJ53890.1 - 9.9 5.6 7.5 17 4.8 7.5 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 SR-25 PF10500.9 CDJ53891.1 - 0.00044 19.9 8.6 0.00044 19.9 8.6 2.3 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein PAP1 PF08601.10 CDJ53891.1 - 0.025 14.3 14.4 0.029 14.1 14.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.9 CDJ53891.1 - 0.37 9.6 12.2 0.47 9.3 12.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 CDJ53891.1 - 2.2 6.3 8.2 2.6 6.0 8.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.6 CDJ53891.1 - 3.4 8.2 11.4 4.5 7.8 11.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GREB1 PF15782.5 CDJ53891.1 - 5.5 4.0 6.6 5.7 3.9 6.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CBF PF03914.17 CDJ53893.1 - 7.3e-19 68.4 0.5 7.3e-19 68.4 0.5 2.3 2 1 0 2 2 2 1 CBF/Mak21 family Spt20 PF12090.8 CDJ53893.1 - 0.00045 19.9 8.8 0.00045 19.9 8.8 2.8 3 0 0 3 3 3 1 Spt20 family TFIIA PF03153.13 CDJ53893.1 - 0.086 12.8 31.1 0.14 12.1 30.2 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EOS1 PF12326.8 CDJ53893.1 - 0.81 9.6 4.4 1.2 9.1 0.7 2.1 2 0 0 2 2 2 0 N-glycosylation protein rRNA_processing PF08524.11 CDJ53893.1 - 0.99 9.4 23.3 0.51 10.4 7.5 2.5 2 0 0 2 2 2 0 rRNA processing DUF3043 PF11241.8 CDJ53893.1 - 6 6.9 18.1 0.092 12.8 6.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) TERB2 PF15101.6 CDJ53893.1 - 6.3 6.8 10.9 0.38 10.8 4.2 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Utp14 PF04615.13 CDJ53894.1 - 0.0023 16.6 30.1 0.0049 15.5 30.1 1.5 1 1 0 1 1 1 1 Utp14 protein DUF2052 PF09747.9 CDJ53894.1 - 0.21 11.7 43.6 1.1 9.3 1.6 3.2 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) DUF572 PF04502.13 CDJ53894.1 - 2 8.0 39.4 1.3 8.5 17.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) tRNA-synt_2 PF00152.20 CDJ53895.1 - 1.3e-78 264.3 0.0 1e-77 261.3 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ53895.1 - 3.8e-08 33.2 0.0 1.1e-07 31.7 0.0 1.7 1 1 1 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDJ53895.1 - 0.003 17.1 0.1 0.018 14.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) SRP-alpha_N PF04086.13 CDJ53896.1 - 4 7.3 10.3 5.6 6.8 10.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DENN PF02141.21 CDJ53901.1 - 2.9e-21 76.3 13.4 2.2e-18 66.9 9.6 2.8 1 1 1 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 CDJ53901.1 - 2.2e-05 25.1 5.0 0.00019 22.1 0.1 3.3 3 0 0 3 3 3 1 uDENN domain C-C_Bond_Lyase PF15617.6 CDJ53901.1 - 0.0046 16.2 0.5 0.0086 15.3 0.5 1.4 1 0 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold Ank_2 PF12796.7 CDJ53903.1 - 1.1e-05 25.9 0.4 3.4e-05 24.3 0.0 2.0 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDJ53903.1 - 0.00037 20.7 0.2 0.0036 17.7 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 CDJ53903.1 - 0.001 19.6 0.3 0.0089 16.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CDJ53903.1 - 0.0053 17.2 4.7 0.015 15.7 0.0 3.7 4 1 0 4 4 4 1 Ankyrin repeat Methyltransf_33 PF10017.9 CDJ53903.1 - 0.065 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.6 CDJ53903.1 - 0.091 13.5 0.0 0.36 11.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain RskA PF10099.9 CDJ53905.1 - 1.4 9.2 13.8 0.89 9.8 11.7 1.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF4616 PF15394.6 CDJ53905.1 - 1.9 7.4 6.2 0.12 11.3 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4616) AMMECR1 PF01871.17 CDJ53906.1 - 5.5e-31 107.4 0.0 5.5e-31 107.4 0.0 2.1 3 0 0 3 3 3 1 AMMECR1 DUF3989 PF13150.6 CDJ53906.1 - 0.071 12.8 0.1 0.071 12.8 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3989) PAT1 PF09770.9 CDJ53906.1 - 2.8 6.1 49.8 4.5 5.4 49.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S46 PF10459.9 CDJ53906.1 - 5.1 5.6 24.8 7 5.2 24.8 1.2 1 0 0 1 1 1 0 Peptidase S46 ABC2_membrane_2 PF12679.7 CDJ53907.1 - 0.00069 19.0 3.3 0.00069 19.0 3.3 2.8 2 1 0 2 2 1 1 ABC-2 family transporter protein Pex14_N PF04695.13 CDJ53907.1 - 0.00085 20.0 21.3 0.00085 20.0 21.3 3.1 2 1 1 3 3 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 CDJ53907.1 - 0.0025 17.9 31.9 0.0025 17.9 31.9 2.9 2 1 1 3 3 1 1 Uncharacterized protein conserved in bacteria (DUF2076) eIF-3_zeta PF05091.12 CDJ53907.1 - 0.0026 16.8 31.1 0.071 12.1 18.0 2.1 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TRAP_alpha PF03896.16 CDJ53907.1 - 0.0033 16.7 1.6 0.0033 16.7 1.6 3.0 3 0 0 3 3 2 1 Translocon-associated protein (TRAP), alpha subunit SpoIIP PF07454.11 CDJ53907.1 - 0.0048 16.4 25.1 0.055 12.9 13.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 CDJ53907.1 - 0.012 15.8 21.0 0.27 11.4 0.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Spore_III_AF PF09581.10 CDJ53907.1 - 0.017 15.1 8.3 0.017 15.1 8.3 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Neur_chan_memb PF02932.16 CDJ53907.1 - 0.017 15.2 21.5 0.081 13.0 0.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Afi1 PF07792.12 CDJ53907.1 - 0.02 15.4 20.1 0.2 12.2 11.0 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pex24p PF06398.11 CDJ53907.1 - 0.022 13.8 0.0 0.022 13.8 0.0 2.0 1 1 0 2 2 1 0 Integral peroxisomal membrane peroxin MFAP1 PF06991.11 CDJ53907.1 - 0.026 14.4 29.0 0.087 12.7 5.1 2.2 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing DUF5308 PF17233.2 CDJ53907.1 - 0.031 14.5 1.6 0.031 14.5 1.6 2.8 2 1 0 2 2 1 0 Family of unknown function (DUF5308) CobT PF06213.12 CDJ53907.1 - 0.033 13.6 35.8 0.059 12.7 18.0 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SID-1_RNA_chan PF13965.6 CDJ53907.1 - 0.053 11.9 13.2 2.9 6.2 13.2 2.0 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 CDJ53907.1 - 0.057 11.3 32.9 0.054 11.4 13.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Gti1_Pac2 PF09729.9 CDJ53907.1 - 0.13 12.3 21.3 0.47 10.5 10.5 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family PIP5K PF01504.18 CDJ53907.1 - 0.13 11.5 19.7 0.095 11.9 8.3 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF3807 PF12720.7 CDJ53907.1 - 0.17 12.2 36.2 0.88 9.8 21.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) EPL1 PF10513.9 CDJ53907.1 - 0.31 11.4 29.6 1.4 9.3 6.0 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like CCSAP PF15748.5 CDJ53907.1 - 0.34 11.0 31.7 0.85 9.7 16.0 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated LAG1-DNAbind PF09271.11 CDJ53907.1 - 0.36 11.5 19.0 0.72 10.5 9.1 2.2 2 0 0 2 2 2 0 LAG1, DNA binding PTPRCAP PF15713.5 CDJ53907.1 - 0.48 10.7 28.2 0.58 10.4 14.4 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated FAM76 PF16046.5 CDJ53907.1 - 0.51 9.7 29.9 0.075 12.4 13.3 2.1 2 0 0 2 2 2 0 FAM76 protein Peptidase_S49_N PF08496.10 CDJ53907.1 - 0.54 10.3 24.9 0.73 9.9 0.7 3.1 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Tim54 PF11711.8 CDJ53907.1 - 0.67 8.7 24.6 0.57 8.9 11.2 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Scs3p PF10261.9 CDJ53907.1 - 0.78 9.2 11.5 3.8 7.0 5.9 2.4 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM CDK2AP PF09806.9 CDJ53907.1 - 0.81 9.7 31.8 0.029 14.4 6.0 2.4 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein Auxin_canalis PF05703.11 CDJ53907.1 - 0.87 9.5 27.3 0.12 12.3 18.1 2.1 2 0 0 2 2 2 0 Auxin canalisation RR_TM4-6 PF06459.12 CDJ53907.1 - 0.89 9.3 28.6 1.4 8.7 3.0 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DAG_kinase_N PF14513.6 CDJ53907.1 - 0.92 9.7 26.0 1.9 8.6 2.8 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF3292 PF11696.8 CDJ53907.1 - 1.1 7.5 22.9 0.83 7.9 14.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) DUF4050 PF13259.6 CDJ53907.1 - 1.4 9.2 23.2 1.9 8.8 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) PRA1 PF03208.19 CDJ53907.1 - 1.6 8.4 5.6 5 6.7 5.5 1.9 3 0 0 3 3 2 0 PRA1 family protein DUF3295 PF11702.8 CDJ53907.1 - 1.9 7.7 32.1 2 7.6 14.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) FAM176 PF14851.6 CDJ53907.1 - 2 8.1 17.4 0.035 13.7 1.8 2.7 3 0 0 3 3 2 0 FAM176 family Pal1 PF08316.11 CDJ53907.1 - 2 9.2 17.8 0.11 13.2 6.6 2.1 2 0 0 2 2 2 0 Pal1 cell morphology protein Ribosomal_60s PF00428.19 CDJ53907.1 - 2.2 8.9 14.9 5.2 7.7 14.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein FAM60A PF15396.6 CDJ53907.1 - 2.7 8.0 21.3 4.8 7.1 11.6 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Mem_trans PF03547.18 CDJ53907.1 - 3.7 5.8 15.0 0.46 8.8 5.4 2.4 3 0 0 3 3 3 0 Membrane transport protein DUF5385 PF17359.2 CDJ53907.1 - 4 6.9 24.9 4.2 6.9 3.7 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5385) EIIBC-GUT_N PF03612.14 CDJ53907.1 - 4.2 7.1 27.6 2.7 7.7 4.4 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus ALMT PF11744.8 CDJ53907.1 - 4.2 6.1 25.5 3.3 6.4 14.8 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter AIF_C PF14721.6 CDJ53907.1 - 4.7 7.6 23.8 0.48 10.8 9.1 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pannexin_like PF12534.8 CDJ53907.1 - 4.9 6.1 22.7 5.7 5.9 2.9 2.2 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 D123 PF07065.14 CDJ53907.1 - 5.2 6.1 19.8 5 6.2 9.3 2.1 2 0 0 2 2 2 0 D123 RPA43_OB PF17875.1 CDJ53907.1 - 6.5 7.4 18.4 7.2 7.3 1.1 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF2370 PF10176.9 CDJ53907.1 - 7 6.2 16.0 12 5.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) YABBY PF04690.13 CDJ53907.1 - 8.6 6.9 28.4 9.5 6.8 4.3 2.2 2 0 0 2 2 2 0 YABBY protein Ureide_permease PF07168.11 CDJ53907.1 - 8.6 5.0 13.9 1.4 7.6 6.3 2.2 2 0 0 2 2 2 0 Ureide permease Membralin PF09746.9 CDJ53907.1 - 9 5.2 19.2 3.6 6.5 10.3 2.2 2 0 0 2 2 2 0 Tumour-associated protein PIG-S PF10510.9 CDJ53907.1 - 9.9 4.9 32.8 6.1 5.5 7.9 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF726 PF05277.12 CDJ53908.1 - 0.24 10.3 1.1 0.26 10.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) CDC45 PF02724.14 CDJ53908.1 - 0.29 9.4 38.6 0.35 9.1 38.6 1.2 1 0 0 1 1 1 0 CDC45-like protein CCSAP PF15748.5 CDJ53908.1 - 0.4 10.8 49.6 0.58 10.3 49.6 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF572 PF04502.13 CDJ53908.1 - 2.1 7.9 37.4 2.8 7.5 37.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4045 PF13254.6 CDJ53908.1 - 7 6.2 40.9 11 5.5 40.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CopD PF05425.13 CDJ53909.1 - 0.047 14.1 2.4 0.1 13.0 2.4 1.7 1 0 0 1 1 1 0 Copper resistance protein D DUF445 PF04286.12 CDJ53909.1 - 0.22 11.3 10.7 0.36 10.6 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AI-2E_transport PF01594.16 CDJ53909.1 - 0.22 10.6 10.5 0.34 10.0 10.5 1.2 1 0 0 1 1 1 0 AI-2E family transporter GNAT_acetyltran PF12746.7 CDJ53909.1 - 0.77 9.3 6.5 1.6 8.2 6.5 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase CDC45 PF02724.14 CDJ53909.1 - 1.2 7.4 21.8 2.6 6.2 21.8 1.7 1 1 0 1 1 1 0 CDC45-like protein DUF1512 PF07431.12 CDJ53909.1 - 1.4 7.8 2.7 2.1 7.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DUF3139 PF11337.8 CDJ53909.1 - 1.4 9.6 5.6 18 6.0 5.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) Tetraspanin PF00335.20 CDJ53909.1 - 1.5 8.5 12.2 17 5.0 12.2 2.4 1 1 0 1 1 1 0 Tetraspanin family TadE PF07811.12 CDJ53909.1 - 7 7.0 10.4 14 6.1 10.4 1.5 1 0 0 1 1 1 0 TadE-like protein RapA_C PF12137.8 CDJ53910.1 - 0.026 13.6 1.6 0.037 13.0 1.6 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Podoplanin PF05808.11 CDJ53910.1 - 0.67 10.0 6.9 0.04 14.0 1.7 1.7 2 1 0 2 2 2 0 Podoplanin Stevor PF17410.2 CDJ53910.1 - 5.1 6.6 10.5 0.092 12.3 0.4 2.1 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame RXLR PF16810.5 CDJ53910.1 - 5.7 7.4 11.9 1.5 9.3 2.8 2.2 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity CysG_dimeriser PF10414.9 CDJ53911.1 - 0.17 11.6 11.9 0.24 11.2 11.9 1.2 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Cluap1 PF10234.9 CDJ53911.1 - 0.42 10.0 11.0 0.49 9.8 11.0 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF3683 PF12447.8 CDJ53911.1 - 0.84 9.8 5.5 1 9.5 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) Exonuc_VII_L PF02601.15 CDJ53911.1 - 5.7 6.4 13.7 6.3 6.3 13.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit RskA PF10099.9 CDJ53912.1 - 0.00087 19.6 14.4 0.00087 19.6 14.4 3.9 2 1 0 2 2 2 1 Anti-sigma-K factor rskA Connexin PF00029.19 CDJ53912.1 - 0.037 13.8 0.6 0.05 13.4 0.6 1.2 1 0 0 1 1 1 0 Connexin FAM76 PF16046.5 CDJ53912.1 - 0.095 12.0 8.4 2.4 7.5 7.1 2.1 2 0 0 2 2 2 0 FAM76 protein SpoIIP PF07454.11 CDJ53912.1 - 0.14 11.5 5.3 0.23 10.9 5.3 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF3408 PF11888.8 CDJ53912.1 - 0.61 10.2 12.7 1.5 9.0 12.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Med15 PF09606.10 CDJ53912.1 - 1.2 7.7 44.6 2 7.0 44.6 1.4 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal OATP PF03137.20 CDJ53912.1 - 1.7 6.8 4.5 2.5 6.3 4.5 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAM60A PF15396.6 CDJ53912.1 - 6.8 6.6 8.3 2 8.4 5.3 1.7 2 0 0 2 2 2 0 Protein Family FAM60A DUF4757 PF15949.5 CDJ53914.1 - 1.7 9.1 10.1 2.5 8.6 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) DUF677 PF05055.12 CDJ53914.1 - 2.2 7.1 5.0 3.1 6.6 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF1635 PF07795.11 CDJ53916.1 - 0.84 9.5 15.9 1.1 9.0 15.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF3123 PF11321.8 CDJ53916.1 - 1.1 9.9 7.2 0.29 11.8 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3123) Lin-8 PF03353.15 CDJ53916.1 - 3.3 7.2 12.2 4.5 6.7 12.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ53916.1 - 7 6.5 20.6 11 5.9 20.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 CDJ53916.1 - 7.8 4.6 13.3 8.2 4.6 13.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S64 PF08192.11 CDJ53916.1 - 8.3 4.8 14.9 9.4 4.6 14.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 RNA_pol_3_Rpc31 PF11705.8 CDJ53917.1 - 0.088 13.0 6.7 0.27 11.5 0.5 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CNDH2_C PF16858.5 CDJ53917.1 - 0.09 12.6 14.0 1.2 9.0 1.1 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term MecA PF05389.12 CDJ53917.1 - 0.23 11.1 7.5 1.8 8.1 1.6 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) TERB2 PF15101.6 CDJ53917.1 - 0.28 11.2 17.4 2 8.4 1.1 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4820 PF16091.5 CDJ53917.1 - 0.43 9.9 13.1 1.2 8.4 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF4834 PF16118.5 CDJ53917.1 - 0.89 10.6 15.3 2.6 9.1 6.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CDC45 PF02724.14 CDJ53917.1 - 1.1 7.5 12.9 0.94 7.7 1.3 2.1 2 0 0 2 2 2 0 CDC45-like protein FAM176 PF14851.6 CDJ53917.1 - 1.2 8.8 13.5 0.71 9.5 2.4 2.3 2 0 0 2 2 2 0 FAM176 family Neur_chan_memb PF02932.16 CDJ53917.1 - 1.5 8.8 10.2 2.8 7.9 4.3 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region AAA_23 PF13476.6 CDJ53917.1 - 1.8 9.1 15.7 5.4 7.5 6.5 2.2 2 0 0 2 2 2 0 AAA domain DUF4484 PF14831.6 CDJ53917.1 - 6.3 6.8 14.1 0.45 10.5 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Paf1 PF03985.13 CDJ53917.1 - 8.3 5.3 23.4 4.3 6.2 9.1 2.1 2 0 0 2 2 2 0 Paf1 PPL5 PF18168.1 CDJ53917.1 - 8.7 5.5 10.0 4.4 6.5 2.1 2.2 2 0 0 2 2 2 0 Prim-pol family 5 SR-25 PF10500.9 CDJ53919.1 - 0.0015 18.1 3.1 0.0015 18.1 3.1 20.1 16 4 3 20 20 20 3 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ53919.1 - 0.0035 17.7 1.3 0.0035 17.7 1.3 22.5 7 5 9 16 16 16 4 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ53919.1 - 0.015 14.9 0.1 0.015 14.9 0.1 21.2 18 4 2 20 20 20 0 Spt20 family Vac7 PF12751.7 CDJ53920.1 - 0.46 9.9 17.1 0.55 9.6 17.1 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF4179 PF13786.6 CDJ53920.1 - 0.73 10.3 5.2 0.33 11.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) CDC27 PF09507.10 CDJ53920.1 - 5.1 6.4 41.1 6.7 6.0 41.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SLC12 PF03522.15 CDJ53920.1 - 5.4 5.9 26.0 7.3 5.5 26.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Scaffolding_pro PF11418.8 CDJ53921.1 - 0.13 12.8 1.3 89 3.7 0.3 3.4 3 0 0 3 3 3 0 Phi29 scaffolding protein LapA_dom PF06305.11 CDJ53921.1 - 7.6 6.4 8.9 1.5 8.7 0.3 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SRR1 PF07985.12 CDJ53922.1 - 4.4e-13 49.1 0.9 9.7e-13 48.0 0.9 1.6 1 0 0 1 1 1 1 SRR1 Suf PF05843.14 CDJ53922.1 - 0.057 13.4 10.1 0.08 12.9 10.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SR-25 PF10500.9 CDJ53922.1 - 0.063 12.9 0.4 0.063 12.9 0.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein eIF-3_zeta PF05091.12 CDJ53922.1 - 0.15 11.0 10.0 0.2 10.6 10.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 CDJ53922.1 - 0.25 10.9 29.0 0.38 10.3 29.0 1.2 1 0 0 1 1 1 0 Spt20 family Serinc PF03348.15 CDJ53922.1 - 0.29 10.0 2.3 0.43 9.5 2.3 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.16 CDJ53922.1 - 0.35 10.9 1.7 0.63 10.1 1.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 CDJ53922.1 - 0.55 8.4 14.8 0.71 8.1 14.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Velvet PF11754.8 CDJ53922.1 - 0.73 9.7 9.1 0.77 9.6 7.6 1.7 2 0 0 2 2 2 0 Velvet factor DUF913 PF06025.12 CDJ53922.1 - 0.96 8.4 4.8 6 5.7 4.9 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 CDJ53922.1 - 1.1 9.4 7.2 2 8.5 7.2 1.4 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.6 CDJ53922.1 - 1.3 9.0 5.4 2.3 8.2 5.4 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF3464 PF11947.8 CDJ53922.1 - 1.8 8.3 7.4 4.1 7.1 7.4 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Coilin_N PF15862.5 CDJ53922.1 - 2.8 7.7 9.8 5.3 6.8 9.8 1.4 1 0 0 1 1 1 0 Coilin N-terminus RR_TM4-6 PF06459.12 CDJ53922.1 - 3.2 7.5 9.9 5 6.9 9.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ53922.1 - 4.2 6.0 12.7 6.1 5.5 12.7 1.2 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 CDJ53922.1 - 5.6 6.3 9.1 16 4.9 9.6 1.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) EIIBC-GUT_N PF03612.14 CDJ53922.1 - 5.6 6.7 7.5 12 5.6 7.5 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus BAF1_ABF1 PF04684.13 CDJ53922.1 - 6.2 5.7 17.7 14 4.5 17.7 1.6 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Baculo_PP31 PF05311.11 CDJ53922.1 - 7.3 6.0 7.5 11 5.3 7.5 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Calreticulin PF00262.18 CDJ53923.1 - 1.3e-20 73.6 0.0 5.3e-12 45.3 0.0 2.1 1 1 1 2 2 2 2 Calreticulin family Cullin_Nedd8 PF10557.9 CDJ53924.1 - 5.4e-08 32.7 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.22 CDJ53924.1 - 0.018 13.7 0.0 0.11 11.1 0.0 1.9 2 0 0 2 2 2 0 Cullin family ComX PF05952.12 CDJ53924.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacillus competence pheromone ComX AAA_6 PF12774.7 CDJ53925.1 - 2e-147 490.4 1.1 2.4e-146 486.9 0.1 3.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ53925.1 - 1.2e-112 377.0 3.5 1.2e-112 377.0 3.5 4.5 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 CDJ53925.1 - 1.1e-72 243.3 0.0 1.3e-66 223.6 0.0 3.7 3 0 0 3 3 3 3 P-loop containing dynein motor region Dynein_C PF18199.1 CDJ53925.1 - 3.6e-62 210.3 1.7 6.2e-46 157.0 0.0 3.5 2 1 1 3 3 2 2 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CDJ53925.1 - 6.5e-54 182.1 0.3 5.5e-53 179.1 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_9 PF12781.7 CDJ53925.1 - 7e-50 169.2 9.8 8.8e-32 110.0 0.1 4.4 3 2 2 5 5 3 2 ATP-binding dynein motor region AAA_8 PF12780.7 CDJ53925.1 - 2.1e-47 161.6 0.9 2.8e-46 157.9 0.1 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.7 CDJ53925.1 - 1.4e-46 159.2 11.5 1.1e-44 152.9 6.3 2.2 2 0 0 2 2 2 2 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CDJ53925.1 - 7.1e-25 87.6 0.0 2.5e-24 85.8 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDJ53925.1 - 1.2e-22 80.4 0.1 3.4e-05 23.8 0.0 7.3 7 1 0 7 7 6 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CDJ53925.1 - 1.4e-21 76.6 0.4 6.6e-21 74.4 0.1 2.4 2 0 0 2 2 1 1 AAA+ lid domain Dynein_heavy PF03028.15 CDJ53925.1 - 9.9e-17 61.1 1.0 2e-09 37.5 0.1 4.6 3 1 1 4 4 4 2 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 CDJ53925.1 - 2.1e-09 37.9 0.5 0.026 14.9 0.0 5.4 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ53925.1 - 9.7e-08 32.4 2.2 0.47 10.7 0.0 4.9 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.6 CDJ53925.1 - 2.4e-05 24.9 0.0 0.21 12.2 0.0 4.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CDJ53925.1 - 5e-05 23.8 4.1 1.9 8.9 0.0 5.7 4 1 0 4 4 4 1 AAA ATPase domain Phage_GP20 PF06810.11 CDJ53925.1 - 0.00026 20.8 11.1 0.00026 20.8 11.1 4.3 4 1 1 5 5 5 1 Phage minor structural protein GP20 RNA_helicase PF00910.22 CDJ53925.1 - 0.0014 19.0 0.0 0.59 10.6 0.0 3.6 3 0 0 3 3 3 1 RNA helicase Mg_chelatase PF01078.21 CDJ53925.1 - 0.0014 18.0 0.7 3.2 7.1 0.0 3.9 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CDJ53925.1 - 0.0028 17.3 2.3 13 5.3 0.0 3.8 3 0 0 3 3 3 0 AAA domain DUF853 PF05872.12 CDJ53925.1 - 0.0031 16.2 11.1 0.42 9.2 0.1 3.9 5 0 0 5 5 4 2 Bacterial protein of unknown function (DUF853) DEAD PF00270.29 CDJ53925.1 - 0.005 16.6 0.0 1.3 8.8 0.0 3.4 3 1 0 3 3 2 1 DEAD/DEAH box helicase T2SSE PF00437.20 CDJ53925.1 - 0.0076 15.3 5.1 0.24 10.4 0.1 3.5 4 0 0 4 4 3 1 Type II/IV secretion system protein DUF4119 PF13494.6 CDJ53925.1 - 0.0076 16.4 0.0 2.2 8.5 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function, B. Theta Gene description (DUF4119) AAA_30 PF13604.6 CDJ53925.1 - 0.02 14.6 6.8 2.1 8.0 0.0 3.8 4 0 0 4 4 3 0 AAA domain TsaE PF02367.17 CDJ53925.1 - 0.033 14.2 0.9 15 5.6 0.1 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 CDJ53925.1 - 0.081 12.5 4.6 6.3 6.4 0.1 4.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CDJ53925.1 - 0.083 13.2 0.3 30 4.9 0.1 3.8 3 0 0 3 3 3 0 AAA domain DASH_Hsk3 PF08227.11 CDJ53925.1 - 0.39 11.1 3.8 2.8 8.4 3.8 2.6 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like MnmE_helical PF12631.7 CDJ53925.1 - 1.3 9.2 9.2 1.9 8.6 0.2 4.4 4 0 0 4 4 4 0 MnmE helical domain AAA_28 PF13521.6 CDJ53925.1 - 1.7 8.9 9.5 7.3 6.8 0.0 4.8 7 0 0 7 7 3 0 AAA domain DUF3138 PF11336.8 CDJ53925.1 - 2 7.0 5.3 3.5 6.1 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spc7 PF08317.11 CDJ53925.1 - 3.2 6.5 44.6 0.16 10.8 6.4 3.9 4 0 0 4 4 4 0 Spc7 kinetochore protein HA2 PF04408.23 CDJ53927.1 - 0.49 10.7 9.8 0.9 9.8 0.4 3.0 3 0 0 3 3 3 0 Helicase associated domain (HA2) Ribosomal_60s PF00428.19 CDJ53927.1 - 2.1 9.0 12.6 0.091 13.4 2.0 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ53928.1 - 5.3e-07 30.0 42.6 1.6e-05 25.1 11.2 2.4 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit SMAP PF15477.6 CDJ53928.1 - 3.9 8.5 15.8 0.087 13.8 1.0 3.5 2 0 0 2 2 2 0 Small acidic protein family Peptidase_C65 PF10275.9 CDJ53929.1 - 2.7e-36 125.3 0.0 1.3e-22 80.5 0.0 2.8 1 1 2 3 3 3 2 Peptidase C65 Otubain DUF2722 PF10846.8 CDJ53929.1 - 0.00036 19.6 0.7 0.00045 19.3 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ53929.1 - 0.00094 19.3 11.0 0.0012 19.0 11.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ53929.1 - 0.0029 17.2 6.3 0.0029 17.2 6.3 1.5 2 0 0 2 2 2 1 Spt20 family RskA PF10099.9 CDJ53929.1 - 0.011 16.0 17.4 0.011 16.0 17.4 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA RYDR_ITPR PF01365.21 CDJ53929.1 - 0.026 14.0 2.2 0.037 13.4 2.2 1.1 1 0 0 1 1 1 0 RIH domain DUF913 PF06025.12 CDJ53929.1 - 0.12 11.4 0.6 0.16 10.9 0.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) IHABP4_N PF16174.5 CDJ53929.1 - 0.15 12.7 7.7 0.22 12.1 7.7 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal GET2 PF08690.10 CDJ53929.1 - 6.4 6.4 7.6 38 3.8 7.6 1.9 1 1 0 1 1 1 0 GET complex subunit GET2 mTERF PF02536.14 CDJ53930.1 - 4.1e-11 42.4 1.1 2.8e-09 36.3 0.0 2.6 3 0 0 3 3 3 2 mTERF SR-25 PF10500.9 CDJ53930.1 - 2.9e-05 23.8 5.6 2.9e-05 23.8 5.6 4.8 5 0 0 5 5 5 1 Nuclear RNA-splicing-associated protein LANC_like PF05147.13 CDJ53930.1 - 0.22 10.1 1.5 0.49 8.9 1.5 1.6 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein BPL_N PF09825.9 CDJ53931.1 - 0.027 13.6 15.9 0.033 13.3 15.9 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Utp14 PF04615.13 CDJ53931.1 - 0.034 12.8 27.7 0.043 12.4 27.7 1.0 1 0 0 1 1 1 0 Utp14 protein DUF572 PF04502.13 CDJ53931.1 - 0.25 10.9 25.6 0.37 10.4 25.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-C4H2 PF10146.9 CDJ53931.1 - 0.27 11.5 25.4 0.4 11.0 25.4 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein VIR_N PF15912.5 CDJ53931.1 - 2 8.0 17.2 3.6 7.1 17.2 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Borrelia_P83 PF05262.11 CDJ53931.1 - 2.2 6.7 32.1 2.4 6.5 32.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CRT10 PF08728.10 CDJ53931.1 - 2.2 6.3 9.1 2.5 6.2 9.1 1.1 1 0 0 1 1 1 0 CRT10 V_ATPase_I PF01496.19 CDJ53931.1 - 2.3 6.0 26.9 2.9 5.7 26.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAT1 PF09770.9 CDJ53931.1 - 5.3 5.2 44.1 6.3 4.9 44.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tyrosinase PF00264.20 CDJ53931.1 - 5.8 7.1 14.6 8.8 6.5 14.6 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase Caldesmon PF02029.15 CDJ53931.1 - 8.3 5.1 33.8 15 4.2 33.8 1.3 1 0 0 1 1 1 0 Caldesmon Draxin PF15550.6 CDJ53931.1 - 10 5.9 19.5 17 5.2 19.5 1.3 1 0 0 1 1 1 0 Draxin IF-2B PF01008.17 CDJ53932.1 - 9.8e-16 57.8 0.4 4.3e-07 29.4 0.0 3.7 1 1 2 3 3 3 3 Initiation factor 2 subunit family SUIM_assoc PF16619.5 CDJ53932.1 - 1.1e-07 31.8 0.0 4.5e-06 26.6 0.0 2.3 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ53932.1 - 0.00044 19.3 3.1 0.00046 19.3 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) FragX_IP PF05994.11 CDJ53932.1 - 0.0033 15.6 0.4 0.0041 15.3 0.4 1.0 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family DUF4834 PF16118.5 CDJ53932.1 - 0.017 16.0 0.6 0.028 15.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) UPF0524 PF15823.5 CDJ53932.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 Spt20 PF12090.8 CDJ53932.1 - 0.14 11.7 16.6 0.2 11.2 16.6 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ53932.1 - 0.18 11.8 12.2 0.22 11.5 12.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NEMP PF10225.9 CDJ53932.1 - 0.22 11.2 0.6 0.32 10.6 0.6 1.2 1 0 0 1 1 1 0 NEMP family UPF0560 PF10577.9 CDJ53932.1 - 1.6 7.2 7.4 2 6.8 7.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Androgen_recep PF02166.16 CDJ53932.1 - 4.4 6.0 16.1 5.8 5.6 16.1 1.1 1 0 0 1 1 1 0 Androgen receptor CAP18_C PF12153.8 CDJ53933.1 - 0.16 11.8 0.4 0.33 10.9 0.4 1.5 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) RVT_1 PF00078.27 CDJ53934.1 - 5e-20 72.0 0.0 8.2e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ53934.1 - 6.4e-14 52.1 0.1 1.4e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ53934.1 - 0.00036 20.5 0.0 0.0007 19.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ53934.1 - 0.00036 20.7 0.0 0.00072 19.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain CNOT1_TTP_bind PF16417.5 CDJ53935.1 - 1.1e-28 99.8 0.0 1.1e-28 99.8 0.0 5.2 5 1 1 6 6 6 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_CAF1_bind PF16415.5 CDJ53935.1 - 2.2e-14 53.4 0.1 3.8e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain HCO3_cotransp PF00955.21 CDJ53935.1 - 1.9 7.2 7.7 4.5 6.0 7.7 1.5 1 0 0 1 1 1 0 HCO3- transporter family SR-25 PF10500.9 CDJ53935.1 - 3.2 7.3 37.4 0.32 10.6 14.5 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF2052 PF09747.9 CDJ53935.1 - 8.4 6.5 40.1 11 6.1 0.8 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Arv1 PF04161.13 CDJ53936.1 - 4.8e-31 108.6 0.0 4.8e-31 108.6 0.0 3.2 5 0 0 5 5 5 1 Arv1-like family SR-25 PF10500.9 CDJ53936.1 - 2.7e-05 23.9 13.9 2.7e-05 23.9 13.9 5.0 5 1 0 5 5 5 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ53936.1 - 2.8e-05 24.5 1.2 2.8e-05 24.5 1.2 4.5 2 2 2 4 4 4 3 Anti-sigma-K factor rskA Nudix_N_2 PF14803.6 CDJ53936.1 - 0.029 14.3 4.4 0.08 12.9 4.4 1.7 1 0 0 1 1 1 0 Nudix N-terminal SPX PF03105.19 CDJ53936.1 - 0.068 13.1 32.8 9.5e+02 -0.6 32.9 2.6 1 1 0 1 1 1 0 SPX domain LMBR1 PF04791.16 CDJ53936.1 - 0.47 9.3 5.6 4.5 6.1 0.3 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein MCU PF04678.13 CDJ53936.1 - 0.83 9.7 13.4 0.12 12.4 2.2 3.2 3 0 0 3 3 3 0 Mitochondrial calcium uniporter Pex14_N PF04695.13 CDJ53936.1 - 3.8 8.2 62.0 0.13 12.9 9.9 4.5 3 1 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CDJ53936.1 - 4.4 6.0 36.5 0.044 12.5 5.2 3.3 3 0 0 3 3 3 0 Presenilin Stevor PF17410.2 CDJ53936.1 - 4.9 6.6 8.5 4.2 6.8 0.1 2.9 3 0 0 3 3 3 0 Subtelomeric Variable Open Reading frame Sec7_N PF12783.7 CDJ53937.1 - 2.1e-11 44.0 4.7 2.1e-11 44.0 4.7 2.9 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mem_trans PF03547.18 CDJ53938.1 - 0.007 14.8 6.1 0.0064 14.9 2.5 2.5 2 0 0 2 2 2 1 Membrane transport protein Spt20 PF12090.8 CDJ53938.1 - 0.01 15.5 13.4 0.01 15.5 13.4 7.8 3 2 2 5 5 5 0 Spt20 family DUF2207 PF09972.9 CDJ53938.1 - 0.76 8.5 0.0 0.76 8.5 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) T2SSF PF00482.23 CDJ53938.1 - 0.83 9.6 0.0 0.83 9.6 0.0 5.9 7 1 1 8 8 8 0 Type II secretion system (T2SS), protein F Esterase PF00756.20 CDJ53939.1 - 0.46 10.1 18.0 0.54 9.9 18.0 1.0 1 0 0 1 1 1 0 Putative esterase DEAD PF00270.29 CDJ53941.1 - 3.9e-22 78.9 7.8 3.9e-22 78.9 7.8 4.1 2 1 2 4 4 4 2 DEAD/DEAH box helicase RPN2_C PF18004.1 CDJ53941.1 - 0.00072 19.5 1.6 0.00072 19.5 1.6 6.6 3 2 1 4 4 4 1 26S proteasome regulatory subunit RPN2 C-terminal domain SPT6_acidic PF14632.6 CDJ53941.1 - 0.011 16.3 4.3 0.011 16.3 4.3 6.3 5 1 0 5 5 5 0 Acidic N-terminal SPT6 Nt_Gln_amidase PF09764.9 CDJ53941.1 - 0.012 15.2 1.8 0.037 13.7 1.8 1.8 1 0 0 1 1 1 0 N-terminal glutamine amidase IMUP PF15761.5 CDJ53941.1 - 0.017 15.8 2.7 0.017 15.8 2.7 6.6 4 1 2 6 6 6 0 Immortalisation up-regulated protein Myc_N PF01056.18 CDJ53941.1 - 0.74 9.7 0.0 0.74 9.7 0.0 4.6 2 2 2 4 4 4 0 Myc amino-terminal region SR-25 PF10500.9 CDJ53942.1 - 2.4e-07 30.6 32.3 3.2e-07 30.2 32.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ53942.1 - 0.0037 17.5 25.8 0.0037 17.5 25.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF755) Cwf_Cwc_15 PF04889.12 CDJ53942.1 - 0.025 14.3 13.3 0.03 14.1 13.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4228 PF14009.6 CDJ53942.1 - 0.031 14.7 17.2 0.038 14.4 17.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Presenilin PF01080.17 CDJ53942.1 - 0.039 12.7 23.3 0.046 12.5 23.3 1.1 1 0 0 1 1 1 0 Presenilin Dsh_C PF12316.8 CDJ53942.1 - 0.094 13.1 25.5 0.12 12.8 25.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TRAP_alpha PF03896.16 CDJ53942.1 - 0.2 10.8 7.2 0.056 12.6 3.5 1.7 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit PAP1 PF08601.10 CDJ53942.1 - 0.21 11.3 30.8 0.25 11.0 30.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 CCDC106 PF15794.5 CDJ53942.1 - 0.26 11.0 29.1 0.32 10.7 29.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SLC12 PF03522.15 CDJ53942.1 - 0.27 10.2 19.0 0.28 10.2 19.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 ASD2 PF08687.11 CDJ53942.1 - 0.37 10.3 21.6 0.41 10.1 21.6 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 FAM60A PF15396.6 CDJ53942.1 - 0.38 10.7 19.2 0.42 10.6 19.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Smg8_Smg9 PF10220.9 CDJ53942.1 - 0.4 8.9 26.0 0.45 8.8 26.0 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Miga PF10265.9 CDJ53942.1 - 0.71 8.8 21.5 0.81 8.6 21.5 1.0 1 0 0 1 1 1 0 Mitoguardin Striatin PF08232.12 CDJ53942.1 - 1.2 9.7 20.9 1.5 9.4 20.9 1.2 1 0 0 1 1 1 0 Striatin family Rtf2 PF04641.12 CDJ53942.1 - 1.5 8.2 17.2 2 7.7 17.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Peroxin-3 PF04882.12 CDJ53942.1 - 1.8 7.4 24.3 2.3 7.1 24.3 1.1 1 0 0 1 1 1 0 Peroxin-3 Mem_trans PF03547.18 CDJ53942.1 - 2 6.7 10.0 2.2 6.6 10.0 1.2 1 0 0 1 1 1 0 Membrane transport protein XRN_M PF17846.1 CDJ53942.1 - 2.1 7.2 11.7 2.4 7.0 11.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain IHABP4_N PF16174.5 CDJ53942.1 - 2.4 8.7 24.2 3 8.4 24.2 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal CDC45 PF02724.14 CDJ53942.1 - 2.4 6.3 19.3 2.7 6.2 19.3 1.0 1 0 0 1 1 1 0 CDC45-like protein SPX PF03105.19 CDJ53942.1 - 2.6 7.9 26.3 3 7.6 26.3 1.1 1 0 0 1 1 1 0 SPX domain DUF3381 PF11861.8 CDJ53942.1 - 2.9 7.7 16.4 4 7.2 16.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Hid1 PF12722.7 CDJ53942.1 - 3.6 5.6 23.4 3.7 5.6 23.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1180 PF06679.12 CDJ53942.1 - 4 7.8 19.5 1.3 9.4 16.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) PNISR PF15996.5 CDJ53942.1 - 6.3 7.0 24.6 8.5 6.6 24.6 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Bul1_C PF04426.12 CDJ53942.1 - 6.8 6.0 17.7 8 5.8 17.7 1.2 1 0 0 1 1 1 0 Bul1 C terminus DivIC PF04977.15 CDJ53942.1 - 7 6.5 20.4 8.4 6.2 9.6 2.3 2 0 0 2 2 2 0 Septum formation initiator Apt1 PF10351.9 CDJ53942.1 - 7.4 5.3 27.4 8.9 5.0 27.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SRP-alpha_N PF04086.13 CDJ53942.1 - 7.9 6.3 24.1 9.7 6.0 24.1 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Suf PF05843.14 CDJ53942.1 - 9.7 6.1 27.2 13 5.7 27.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RskA PF10099.9 CDJ53943.1 - 0.26 11.5 9.5 0.3 11.4 9.5 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3138 PF11336.8 CDJ53943.1 - 0.33 9.5 7.9 0.34 9.5 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TALPID3 PF15324.6 CDJ53943.1 - 0.64 7.6 8.1 0.58 7.8 8.1 1.0 1 0 0 1 1 1 0 Hedgehog signalling target SAT PF16073.5 CDJ53943.1 - 1 9.0 7.9 1.3 8.7 7.9 1.0 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis S-AdoMet_synt_M PF02772.16 CDJ53945.1 - 9.2e-44 148.5 0.0 1.8e-43 147.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CDJ53945.1 - 1.1e-43 148.0 0.2 2.3e-43 146.9 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_C PF02773.16 CDJ53945.1 - 2e-15 57.0 0.0 6.1e-14 52.2 0.0 2.7 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, C-terminal domain KGK PF08872.10 CDJ53946.1 - 3.2 8.3 10.4 1 9.9 4.6 2.1 2 0 0 2 2 2 0 KGK domain Robl_LC7 PF03259.17 CDJ53946.1 - 8.4 6.2 9.8 8.1 6.3 5.8 2.3 2 0 0 2 2 2 0 Roadblock/LC7 domain LRR_6 PF13516.6 CDJ53947.1 - 0.00039 20.2 1.1 2 8.7 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeat SR-25 PF10500.9 CDJ53947.1 - 0.0004 20.1 9.4 0.0004 20.1 9.4 9.9 7 3 3 10 10 10 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ53947.1 - 0.00085 19.0 9.3 0.00085 19.0 9.3 11.0 7 1 2 9 9 9 5 Spt20 family FmiP_Thoc5 PF09766.9 CDJ53947.1 - 0.004 16.5 7.8 0.004 16.5 7.8 8.0 7 1 0 7 7 7 3 Fms-interacting protein/Thoc5 Carb_kinase PF01256.17 CDJ53948.1 - 1.8e-17 63.6 0.0 1.8e-17 63.6 0.0 3.0 3 1 0 3 3 3 1 Carbohydrate kinase SUIM_assoc PF16619.5 CDJ53948.1 - 0.0083 16.2 3.3 0.0083 16.2 3.3 2.9 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ53948.1 - 0.03 13.9 9.4 0.055 13.1 6.4 2.0 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ53948.1 - 0.26 11.2 13.9 0.074 13.0 6.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ53948.1 - 0.86 7.6 13.7 0.17 9.9 1.9 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein GET2 PF08690.10 CDJ53948.1 - 1.7 8.2 5.7 0.24 11.0 1.3 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 Cys_Met_Meta_PP PF01053.20 CDJ53949.1 - 0.011 14.3 1.9 0.016 13.7 1.9 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Miga PF10265.9 CDJ53949.1 - 0.043 12.8 0.6 0.047 12.7 0.6 1.1 1 0 0 1 1 1 0 Mitoguardin AUX_IAA PF02309.16 CDJ53949.1 - 0.096 12.5 1.9 0.14 12.0 1.9 1.2 1 0 0 1 1 1 0 AUX/IAA family Spt20 PF12090.8 CDJ53949.1 - 0.13 11.8 8.0 0.15 11.7 8.0 1.2 1 0 0 1 1 1 0 Spt20 family MCR_alpha PF02249.17 CDJ53949.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.7 3 0 0 3 3 3 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain TMEM51 PF15345.6 CDJ53949.1 - 0.24 11.2 5.4 0.45 10.3 5.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Spt20 PF12090.8 CDJ53950.1 - 0.65 9.6 23.8 0.61 9.7 23.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF4407 PF14362.6 CDJ53950.1 - 4.5 6.5 10.7 4.6 6.5 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDJ53950.1 - 5.4 6.9 22.7 5.4 6.9 22.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ53950.1 - 5.7 5.9 13.3 5.7 5.9 13.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SR-25 PF10500.9 CDJ53951.1 - 0.00033 20.3 9.0 0.00033 20.3 9.0 9.7 3 1 5 9 9 9 1 Nuclear RNA-splicing-associated protein Nmad5 PF18757.1 CDJ53953.1 - 0.02 15.1 0.1 0.02 15.1 0.1 2.6 3 0 0 3 3 3 0 Nucleotide modification associated domain 5 zf-RanBP PF00641.18 CDJ53954.1 - 2.8e-15 55.3 20.0 1.5e-09 37.0 4.8 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-P11 PF03854.14 CDJ53954.1 - 0.008 15.8 3.8 0.54 10.0 0.2 2.2 2 0 0 2 2 2 2 P-11 zinc finger Spt20 PF12090.8 CDJ53954.1 - 0.089 12.4 9.1 0.12 12.0 9.1 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ53954.1 - 0.12 12.4 16.6 0.16 12.0 16.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RecR PF02132.15 CDJ53954.1 - 0.99 9.0 6.5 0.37 10.4 0.9 2.3 2 0 0 2 2 2 0 RecR protein zf-ribbon_3 PF13248.6 CDJ53954.1 - 2.7 7.5 14.0 3.3 7.2 0.5 3.4 3 0 0 3 3 3 0 zinc-ribbon domain PNISR PF15996.5 CDJ53954.1 - 3.9 7.7 24.2 5.5 7.2 24.2 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR PP2C PF00481.21 CDJ53956.1 - 2.5e-58 197.7 12.7 2.4e-51 174.8 0.0 4.8 6 0 0 6 6 6 3 Protein phosphatase 2C DUF4820 PF16091.5 CDJ53956.1 - 8.1 5.7 11.8 22 4.3 11.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Cytochrom_B561 PF03188.16 CDJ53957.1 - 3.8e-13 49.8 2.7 3.8e-13 49.8 2.7 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Spt20 PF12090.8 CDJ53958.1 - 0.0029 17.2 1.4 0.0029 17.2 1.4 1.7 2 0 0 2 2 2 1 Spt20 family TFIIA PF03153.13 CDJ53958.1 - 2.4 8.1 13.9 5.5 6.9 12.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HTH_15 PF12324.8 CDJ53960.1 - 0.0069 16.3 0.2 0.024 14.6 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase Arf PF00025.21 CDJ53961.1 - 9.9e-31 106.5 0.0 1.2e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CDJ53961.1 - 9.2e-05 22.1 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDJ53961.1 - 0.0005 19.6 0.0 0.0063 16.0 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CDJ53961.1 - 0.03 14.6 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Band_7_C PF16200.5 CDJ53962.1 - 3e-20 72.0 0.1 1.1e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7 PF01145.25 CDJ53962.1 - 1.2e-19 71.0 5.0 1.4e-11 44.8 0.2 2.7 2 1 1 3 3 3 2 SPFH domain / Band 7 family Band_7_1 PF13421.6 CDJ53962.1 - 0.0069 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family 2OG-FeII_Oxy_3 PF13640.6 CDJ53963.1 - 7.4e-08 33.2 0.0 2.4e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TMEM234 PF10639.9 CDJ53964.1 - 3.1e-14 53.0 3.2 1.3e-06 28.5 1.1 2.0 1 1 1 2 2 2 2 Putative transmembrane family 234 Pex14_N PF04695.13 CDJ53964.1 - 0.0002 22.1 10.1 0.00023 21.8 10.1 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region OATP PF03137.20 CDJ53964.1 - 0.00034 19.0 0.4 0.00038 18.9 0.4 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family O-antigen_lig PF13425.6 CDJ53964.1 - 0.00035 19.5 0.5 0.0004 19.3 0.5 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein SpoIIP PF07454.11 CDJ53964.1 - 0.00066 19.2 2.5 0.00069 19.2 2.5 1.0 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) CLN3 PF02487.17 CDJ53964.1 - 0.00073 18.7 2.9 0.0008 18.6 2.9 1.0 1 0 0 1 1 1 1 CLN3 protein Connexin PF00029.19 CDJ53964.1 - 0.00096 19.0 1.3 0.0011 18.8 1.3 1.1 1 0 0 1 1 1 1 Connexin DUF3464 PF11947.8 CDJ53964.1 - 0.0045 16.7 2.3 0.0066 16.2 2.3 1.3 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 DDHD PF02862.17 CDJ53964.1 - 0.0051 17.0 0.6 0.0051 17.0 0.6 1.1 1 0 0 1 1 1 1 DDHD domain Serinc PF03348.15 CDJ53964.1 - 0.0054 15.7 0.3 0.006 15.6 0.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) EPL1 PF10513.9 CDJ53964.1 - 0.0058 17.0 4.0 0.0061 17.0 4.0 1.1 1 0 0 1 1 1 1 Enhancer of polycomb-like DUF2828 PF11443.8 CDJ53964.1 - 0.0068 14.6 1.1 0.0072 14.5 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) CSG2 PF16965.5 CDJ53964.1 - 0.011 14.8 0.7 0.011 14.8 0.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator EMC3_TMCO1 PF01956.16 CDJ53964.1 - 0.021 14.6 10.6 0.027 14.2 10.6 1.3 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Kei1 PF08552.11 CDJ53964.1 - 0.024 14.5 0.2 0.027 14.3 0.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Dynamin_N PF00350.23 CDJ53964.1 - 0.031 14.4 0.4 0.031 14.3 0.4 1.1 1 0 0 1 1 1 0 Dynamin family DUF1980 PF09323.10 CDJ53964.1 - 0.033 14.1 3.1 0.041 13.8 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Peroxin-13_N PF04088.13 CDJ53964.1 - 0.033 14.5 1.2 0.045 14.0 1.2 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Bestrophin PF01062.21 CDJ53964.1 - 0.033 13.6 2.7 0.039 13.3 2.7 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Ctr PF04145.15 CDJ53964.1 - 0.04 14.5 1.3 0.042 14.5 1.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family SID-1_RNA_chan PF13965.6 CDJ53964.1 - 0.041 12.3 0.1 0.04 12.4 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 CDJ53964.1 - 0.042 13.7 6.0 0.049 13.5 6.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Scs3p PF10261.9 CDJ53964.1 - 0.047 13.2 1.2 0.05 13.1 1.2 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Tim54 PF11711.8 CDJ53964.1 - 0.052 12.3 4.5 0.061 12.1 4.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pet20 PF08692.10 CDJ53964.1 - 0.053 14.2 1.6 0.067 13.9 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial protein Pet20 eIF-3_zeta PF05091.12 CDJ53964.1 - 0.073 12.0 8.5 0.076 12.0 8.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 CDJ53964.1 - 0.088 13.0 6.3 0.11 12.7 6.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal G0-G1_switch_2 PF15103.6 CDJ53964.1 - 0.088 13.2 3.7 0.14 12.6 3.7 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 PepSY_TM PF03929.16 CDJ53964.1 - 0.12 12.1 1.0 0.11 12.1 1.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region V_ATPase_I PF01496.19 CDJ53964.1 - 0.12 10.3 7.6 0.14 10.1 7.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MscS_TM PF12794.7 CDJ53964.1 - 0.17 10.7 8.5 0.2 10.4 8.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 EIIBC-GUT_N PF03612.14 CDJ53964.1 - 0.19 11.4 5.9 0.23 11.2 5.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RED_N PF07808.13 CDJ53964.1 - 0.19 11.3 10.7 0.25 10.9 10.7 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region 60KD_IMP PF02096.20 CDJ53964.1 - 0.3 10.9 11.4 0.39 10.6 11.4 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein DUF2126 PF09899.9 CDJ53964.1 - 0.32 9.0 5.2 0.37 8.8 5.2 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Neur_chan_memb PF02932.16 CDJ53964.1 - 0.39 10.7 3.3 0.47 10.5 3.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.16 CDJ53964.1 - 0.41 9.5 5.9 0.51 9.2 5.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Folliculin PF11704.8 CDJ53964.1 - 0.54 10.1 5.6 0.67 9.8 5.6 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport YABBY PF04690.13 CDJ53964.1 - 0.65 10.6 5.1 0.8 10.2 5.1 1.1 1 0 0 1 1 1 0 YABBY protein PTPRCAP PF15713.5 CDJ53964.1 - 0.7 10.2 12.5 0.9 9.8 12.5 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated VIT1 PF01988.19 CDJ53964.1 - 0.71 9.7 2.1 0.78 9.6 2.1 1.2 1 0 0 1 1 1 0 VIT family HemX PF04375.14 CDJ53964.1 - 0.78 9.0 23.2 0.82 8.9 23.2 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF702 PF05142.12 CDJ53964.1 - 0.9 10.0 8.3 1.2 9.6 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) SPT16 PF08644.11 CDJ53964.1 - 1.4 9.0 11.5 2.1 8.5 11.5 1.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) FAM60A PF15396.6 CDJ53964.1 - 1.8 8.5 5.4 2.2 8.3 5.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TERB2 PF15101.6 CDJ53964.1 - 2.8 8.0 17.8 3.4 7.7 17.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PigN PF04987.14 CDJ53964.1 - 4.8 5.9 8.3 14 4.4 8.3 1.8 1 1 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) EIF4E-T PF10477.9 CDJ53964.1 - 5.4 5.7 16.9 6.3 5.5 16.9 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E ALMT PF11744.8 CDJ53964.1 - 9.6 4.9 8.5 12 4.6 8.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Stig1 PF04885.13 CDJ53964.1 - 9.6 6.7 7.8 13 6.3 7.8 1.1 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 SR-25 PF10500.9 CDJ53966.1 - 0.00024 20.8 16.5 0.00024 20.8 16.5 3.6 3 1 0 3 3 3 2 Nuclear RNA-splicing-associated protein SIP1 PF04938.12 CDJ53966.1 - 0.0018 18.0 26.7 0.0018 18.0 26.7 3.0 2 2 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) WBP-1 PF11669.8 CDJ53966.1 - 0.064 13.9 0.4 0.064 13.9 0.4 5.0 4 1 1 5 5 5 0 WW domain-binding protein 1 SPX PF03105.19 CDJ53966.1 - 0.078 12.9 35.7 0.017 15.0 20.1 2.8 2 1 0 2 2 2 0 SPX domain PAT1 PF09770.9 CDJ53966.1 - 0.19 10.0 71.8 0.007 14.7 24.7 3.0 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 Consortin_C PF15281.6 CDJ53966.1 - 0.27 11.2 0.0 0.27 11.2 0.0 3.6 3 0 0 3 3 3 0 Consortin C-terminus Cwf_Cwc_15 PF04889.12 CDJ53966.1 - 1.2 8.9 47.0 0.066 12.9 6.4 3.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein RR_TM4-6 PF06459.12 CDJ53966.1 - 4 7.2 48.7 1.8 8.3 9.8 3.3 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 Endostatin PF06482.11 CDJ53966.1 - 4 6.8 41.9 1.6 8.1 3.8 3.2 3 0 0 3 3 3 0 Collagenase NC10 and Endostatin MMR1 PF08505.10 CDJ53966.1 - 8.6 6.6 58.2 4 7.6 9.6 3.2 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein His_Phos_1 PF00300.22 CDJ53967.1 - 8.1e-19 68.1 8.2 3.6e-07 30.1 0.0 3.3 1 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) TFIIA PF03153.13 CDJ53967.1 - 0.014 15.5 12.6 0.017 15.2 12.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ53967.1 - 0.014 15.0 11.4 0.016 14.9 11.4 1.1 1 0 0 1 1 1 0 Spt20 family IER PF05760.12 CDJ53967.1 - 0.016 15.5 5.1 0.017 15.5 5.1 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF2722 PF10846.8 CDJ53967.1 - 0.025 13.5 8.4 0.03 13.3 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Virul_Fac PF10139.9 CDJ53967.1 - 0.12 10.6 4.3 0.15 10.3 4.3 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor Herpes_DNAp_acc PF04929.12 CDJ53967.1 - 0.14 11.1 4.5 0.17 10.8 4.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Pex14_N PF04695.13 CDJ53967.1 - 0.42 11.3 12.7 0.65 10.6 12.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 CDJ53967.1 - 0.42 9.2 4.4 0.47 9.1 4.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Roughex PF06020.11 CDJ53967.1 - 0.94 8.5 4.4 1.1 8.2 4.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Activator_LAG-3 PF11498.8 CDJ53967.1 - 1.3 7.9 21.5 2.2 7.1 21.5 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 E_Pc_C PF06752.12 CDJ53967.1 - 3.5 7.7 18.6 6.2 6.9 18.6 1.4 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus DUF1180 PF06679.12 CDJ53967.1 - 4.2 7.7 13.0 6.6 7.1 13.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PI3K_1B_p101 PF10486.9 CDJ53968.1 - 0.056 11.2 17.2 0.061 11.1 17.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Peptidase_S49_N PF08496.10 CDJ53968.1 - 0.25 11.4 28.6 0.3 11.1 11.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Spt20 PF12090.8 CDJ53968.1 - 0.45 10.1 87.7 0.095 12.3 33.3 2.3 2 0 0 2 2 2 0 Spt20 family BAF1_ABF1 PF04684.13 CDJ53968.1 - 0.74 8.8 29.2 0.84 8.6 29.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MAM33 PF02330.16 CDJ53968.1 - 0.76 9.7 31.0 0.43 10.5 9.0 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein FAM176 PF14851.6 CDJ53968.1 - 4.5 6.9 28.0 4 7.1 8.2 2.1 2 0 0 2 2 2 0 FAM176 family SLC12 PF03522.15 CDJ53968.1 - 5.2 6.0 33.8 6.9 5.6 33.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Rrp15p PF07890.12 CDJ53968.1 - 7.9 6.8 39.9 0.11 12.8 13.1 2.2 2 0 0 2 2 2 0 Rrp15p TAF4 PF05236.14 CDJ53971.1 - 0.013 15.3 13.6 0.015 15.1 13.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4813 PF16072.5 CDJ53971.1 - 0.049 13.3 12.2 0.056 13.1 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Plasmodium_Vir PF05795.11 CDJ53971.1 - 0.3 10.5 5.4 0.41 10.0 5.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SARAF PF06682.12 CDJ53971.1 - 1.8 8.1 13.4 2.4 7.7 13.4 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis BAF1_ABF1 PF04684.13 CDJ53971.1 - 2.2 7.2 15.6 2.8 6.9 15.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SLC12 PF03522.15 CDJ53971.1 - 4 6.4 10.4 5 6.0 10.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CytochromB561_N PF09786.9 CDJ53971.1 - 6.9 5.5 22.2 7.9 5.3 22.2 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal zf-B_box PF00643.24 CDJ53972.1 - 0.00086 19.4 0.4 0.001 19.2 0.4 1.1 1 0 0 1 1 1 1 B-box zinc finger Androgen_recep PF02166.16 CDJ53972.1 - 0.012 14.5 4.2 0.013 14.3 4.2 1.0 1 0 0 1 1 1 0 Androgen receptor SID-1_RNA_chan PF13965.6 CDJ53973.1 - 0.00036 19.1 6.2 0.00041 18.9 6.2 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 GREB1 PF15782.5 CDJ53973.1 - 0.0024 15.1 31.5 0.0028 14.9 31.5 1.2 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer Rrn6 PF10214.9 CDJ53973.1 - 0.01 14.4 30.4 0.011 14.3 30.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF908 PF06012.12 CDJ53973.1 - 0.01 15.3 20.8 0.013 14.9 20.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Connexin PF00029.19 CDJ53973.1 - 0.023 14.5 14.1 0.036 13.8 14.1 1.4 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 CDJ53973.1 - 0.023 13.7 17.9 0.033 13.2 17.9 1.3 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 CDJ53973.1 - 0.064 12.1 19.4 0.086 11.7 19.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter PA26 PF04636.13 CDJ53973.1 - 0.082 11.8 18.7 0.11 11.4 18.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SAPS PF04499.15 CDJ53973.1 - 0.13 11.0 16.8 0.16 10.7 16.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SART-1 PF03343.13 CDJ53973.1 - 0.15 10.6 27.7 0.18 10.3 27.7 1.1 1 0 0 1 1 1 0 SART-1 family Tim54 PF11711.8 CDJ53973.1 - 0.16 10.8 23.2 0.24 10.1 23.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GAGA_bind PF06217.12 CDJ53973.1 - 0.19 12.0 20.2 0.22 11.8 20.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Hamartin PF04388.12 CDJ53973.1 - 0.2 10.3 28.3 0.26 9.9 28.3 1.2 1 0 0 1 1 1 0 Hamartin protein eIF-3_zeta PF05091.12 CDJ53973.1 - 0.21 10.6 35.0 0.27 10.2 35.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDRGK PF09756.9 CDJ53973.1 - 0.24 11.0 35.3 0.34 10.5 35.3 1.1 1 0 0 1 1 1 0 DDRGK domain Otopetrin PF03189.13 CDJ53973.1 - 0.25 10.1 12.7 0.4 9.4 12.7 1.4 1 0 0 1 1 1 0 Otopetrin Plasmodium_Vir PF05795.11 CDJ53973.1 - 0.35 10.3 13.4 0.48 9.8 13.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 CDJ53973.1 - 0.37 10.7 21.6 0.54 10.1 21.6 1.2 1 0 0 1 1 1 0 SPX domain DUF1387 PF07139.11 CDJ53973.1 - 0.41 10.3 27.6 0.57 9.9 27.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) FapA PF03961.13 CDJ53973.1 - 0.52 8.8 15.5 0.67 8.5 15.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sec62 PF03839.16 CDJ53973.1 - 0.61 9.6 18.4 0.93 9.0 18.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Vfa1 PF08432.10 CDJ53973.1 - 0.72 10.2 28.2 1.2 9.5 28.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPP4R2 PF09184.11 CDJ53973.1 - 0.9 9.1 15.8 1.2 8.7 15.8 1.1 1 0 0 1 1 1 0 PPP4R2 Membralin PF09746.9 CDJ53973.1 - 1.3 8.0 19.2 1.8 7.5 19.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein FAM60A PF15396.6 CDJ53973.1 - 1.5 8.8 22.1 2.3 8.2 22.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A AF-4 PF05110.13 CDJ53973.1 - 1.5 6.8 36.2 1.9 6.4 36.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Apt1 PF10351.9 CDJ53973.1 - 1.8 7.4 21.3 2.3 7.0 21.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain LMBR1 PF04791.16 CDJ53973.1 - 1.9 7.3 12.1 2.4 7.0 12.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein BORG_CEP PF14957.6 CDJ53973.1 - 2.4 9.3 20.1 4 8.6 20.1 1.4 1 0 0 1 1 1 0 Cdc42 effector O-antigen_lig PF13425.6 CDJ53973.1 - 2.9 6.6 13.1 4.3 6.0 13.1 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Pkinase_fungal PF17667.1 CDJ53973.1 - 3.2 6.4 13.7 4.5 5.9 13.7 1.3 1 0 0 1 1 1 0 Fungal protein kinase CDK5_activator PF03261.15 CDJ53973.1 - 3.4 7.1 23.2 4.7 6.7 23.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SLC12 PF03522.15 CDJ53973.1 - 3.4 6.6 32.0 4.7 6.1 32.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 LicD PF04991.13 CDJ53973.1 - 5.5 7.1 8.9 7.3 6.7 8.9 1.1 1 0 0 1 1 1 0 LicD family CSG2 PF16965.5 CDJ53973.1 - 5.7 5.8 15.3 8 5.3 15.3 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator FliP PF00813.20 CDJ53973.1 - 6 6.7 12.9 12 5.7 12.9 1.6 1 0 0 1 1 1 0 FliP family Cellulose_synt PF03552.14 CDJ53973.1 - 6.4 5.1 13.0 8.7 4.7 13.0 1.1 1 0 0 1 1 1 0 Cellulose synthase VIR_N PF15912.5 CDJ53973.1 - 6.5 6.3 15.0 8.9 5.8 15.0 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal MRP-S31 PF15433.6 CDJ53973.1 - 6.6 6.3 28.6 11 5.5 28.6 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 NPR3 PF03666.13 CDJ53973.1 - 7.5 5.2 29.0 10 4.7 29.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PIP5K PF01504.18 CDJ53973.1 - 8.6 5.5 23.0 13 5.0 23.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase PNISR PF15996.5 CDJ53974.1 - 1.3 9.2 44.0 1.7 8.9 44.0 1.0 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Macoilin PF09726.9 CDJ53974.1 - 7.6 5.0 25.2 8.8 4.7 25.2 1.1 1 0 0 1 1 1 0 Macoilin family PNTB PF02233.16 CDJ53976.1 - 7.3e-25 87.8 0.0 1.8e-22 79.9 0.0 2.6 2 1 1 3 3 3 2 NAD(P) transhydrogenase beta subunit TFIIA PF03153.13 CDJ53976.1 - 0.0039 17.2 5.1 0.0039 17.2 5.1 2.5 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit TPP_enzyme_M PF00205.22 CDJ53976.1 - 0.0048 16.6 0.1 0.009 15.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Roughex PF06020.11 CDJ53976.1 - 0.075 12.1 8.2 0.19 10.8 8.2 1.6 1 0 0 1 1 1 0 Drosophila roughex protein DUF5421 PF17458.2 CDJ53976.1 - 2.7 7.3 16.7 5.2 6.4 16.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5421) SPX PF03105.19 CDJ53976.1 - 6.3 6.6 24.2 0.11 12.4 6.7 2.1 2 0 0 2 2 2 0 SPX domain SUIM_assoc PF16619.5 CDJ53977.1 - 0.13 12.4 13.3 0.06 13.4 6.9 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF243 PF03103.17 CDJ53977.1 - 0.19 12.1 5.0 0.18 12.2 0.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF243) YajC PF02699.15 CDJ53977.1 - 3.7 7.5 5.7 1.9 8.4 3.4 1.6 2 0 0 2 2 2 0 Preprotein translocase subunit DUF89 PF01937.19 CDJ53978.1 - 2.2e-07 30.2 0.6 2e-06 27.0 0.5 2.5 1 1 0 1 1 1 1 Protein of unknown function DUF89 COX2 PF00116.20 CDJ53979.1 - 0.0059 16.5 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain RskA PF10099.9 CDJ53981.1 - 0.056 13.7 23.8 0.065 13.5 23.8 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA IHABP4_N PF16174.5 CDJ53981.1 - 1.7 9.2 13.9 2.2 8.9 13.9 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4179 PF13786.6 CDJ53981.1 - 2.6 8.6 7.7 4.6 7.8 7.6 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) Spt20 PF12090.8 CDJ53981.1 - 9.5 5.8 17.5 9.2 5.8 17.5 1.1 1 0 0 1 1 1 0 Spt20 family SWIRM-assoc_2 PF16496.5 CDJ53982.1 - 0.073 11.9 23.0 0.089 11.7 23.0 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal SLC12 PF03522.15 CDJ53982.1 - 0.25 10.3 32.4 0.27 10.2 32.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ53982.1 - 0.58 8.9 39.3 0.71 8.6 39.3 1.0 1 0 0 1 1 1 0 Presenilin FapA PF03961.13 CDJ53982.1 - 0.87 8.1 20.1 0.9 8.1 20.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rtf2 PF04641.12 CDJ53982.1 - 2.4 7.4 25.5 3.7 6.8 25.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger FAM60A PF15396.6 CDJ53982.1 - 4.5 7.2 31.1 5.8 6.9 31.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Spore_coat_CotO PF14153.6 CDJ53982.1 - 4.6 7.1 41.3 7.2 6.5 41.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO AAA_11 PF13086.6 CDJ53982.1 - 4.7 6.9 31.8 5.6 6.7 31.8 1.1 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 CDJ53982.1 - 9.2 6.2 26.6 14 5.6 26.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 CDJ53983.1 - 0.0064 17.4 4.6 0.0064 17.4 4.6 4.6 5 0 0 5 5 5 2 Domain of unknown function (DUF4834) SPX PF03105.19 CDJ53983.1 - 8.7 6.1 62.2 0.14 12.0 28.9 2.9 2 1 0 2 2 2 0 SPX domain Secretin_N_2 PF07655.13 CDJ53984.1 - 0.02 15.4 8.2 0.02 15.4 8.2 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain TFIIA PF03153.13 CDJ53984.1 - 0.027 14.5 19.0 0.032 14.2 19.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TCP PF03634.13 CDJ53984.1 - 0.04 14.5 7.8 0.055 14.0 7.8 1.3 1 0 0 1 1 1 0 TCP family transcription factor S_4TM PF18159.1 CDJ53984.1 - 0.05 12.9 3.2 0.063 12.6 3.2 1.2 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain PIF2 PF04631.12 CDJ53984.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Per os infectivity factor 2 CCSAP PF15748.5 CDJ53984.1 - 0.17 12.0 17.4 0.22 11.7 17.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4834 PF16118.5 CDJ53984.1 - 0.34 11.9 5.7 0.5 11.4 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DDHD PF02862.17 CDJ53984.1 - 0.37 10.9 6.0 0.48 10.6 6.0 1.3 1 0 0 1 1 1 0 DDHD domain BAF1_ABF1 PF04684.13 CDJ53984.1 - 0.46 9.5 10.1 0.7 8.9 10.1 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ndc1_Nup PF09531.10 CDJ53984.1 - 0.47 9.1 8.8 0.5 9.0 8.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PA26 PF04636.13 CDJ53984.1 - 0.6 9.0 4.3 0.7 8.7 4.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 CDJ53984.1 - 1.2 7.8 8.6 1.5 7.5 8.6 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 CDJ53984.1 - 1.5 7.2 6.5 1.6 7.1 6.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Hamartin PF04388.12 CDJ53984.1 - 1.6 7.3 6.7 1.7 7.2 6.7 1.1 1 0 0 1 1 1 0 Hamartin protein Roughex PF06020.11 CDJ53984.1 - 2.8 6.9 8.1 3.6 6.6 8.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Hid1 PF12722.7 CDJ53984.1 - 4 5.4 8.3 4.5 5.3 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF966 PF06136.13 CDJ53984.1 - 4.2 7.0 12.7 5 6.7 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SMYLE_N PF18615.1 CDJ53984.1 - 7.1 6.1 11.5 8.1 5.9 11.5 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SOBP PF15279.6 CDJ53984.1 - 8.9 6.8 10.6 11 6.5 10.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PepSY_TM PF03929.16 CDJ53985.1 - 0.0071 16.0 8.8 0.01 15.5 8.8 1.2 1 0 0 1 1 1 1 PepSY-associated TM region Activator_LAG-3 PF11498.8 CDJ53985.1 - 0.072 12.1 66.3 0.083 11.8 66.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ocular_alb PF02101.15 CDJ53985.1 - 0.14 11.0 1.7 0.16 10.8 1.7 1.0 1 0 0 1 1 1 0 Ocular albinism type 1 protein OATP PF03137.20 CDJ53985.1 - 0.65 8.2 7.5 0.81 7.9 7.5 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ureide_permease PF07168.11 CDJ53985.1 - 0.78 8.4 4.3 0.94 8.2 4.3 1.2 1 0 0 1 1 1 0 Ureide permease Neur_chan_memb PF02932.16 CDJ53985.1 - 1.2 9.2 13.3 1.4 9.0 13.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ctr PF04145.15 CDJ53985.1 - 1.3 9.7 13.0 3.1 8.4 13.0 1.6 1 1 0 1 1 1 0 Ctr copper transporter family G6B PF15096.6 CDJ53985.1 - 1.5 8.5 5.7 1.6 8.5 5.3 1.3 1 1 0 1 1 1 0 G6B family CLN3 PF02487.17 CDJ53985.1 - 1.8 7.5 11.7 2.4 7.1 11.7 1.2 1 0 0 1 1 1 0 CLN3 protein DUF1180 PF06679.12 CDJ53985.1 - 2.5 8.5 7.2 4.2 7.8 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF913 PF06025.12 CDJ53985.1 - 3.3 6.6 11.6 4.2 6.3 11.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.6 CDJ53985.1 - 3.9 5.8 7.3 4.7 5.5 7.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 CDJ53985.1 - 5.9 6.0 10.2 7.1 5.7 10.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RskA PF10099.9 CDJ53986.1 - 0.013 15.8 10.8 0.013 15.8 10.8 6.7 1 1 4 6 6 6 0 Anti-sigma-K factor rskA Peptidase_M56 PF05569.11 CDJ53986.1 - 2.4 7.2 13.9 0.06 12.5 5.4 2.5 2 0 0 2 2 2 0 BlaR1 peptidase M56 RskA PF10099.9 CDJ53989.1 - 0.00095 19.5 0.1 0.00095 19.5 0.1 12.5 4 2 3 7 7 7 2 Anti-sigma-K factor rskA RskA PF10099.9 CDJ53990.1 - 0.0064 16.8 9.6 0.0064 16.8 9.6 6.4 1 1 4 5 5 5 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ53990.1 - 0.015 16.2 5.4 0.015 16.2 5.4 6.3 4 2 2 6 6 6 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ53992.1 - 2.4e-05 23.5 104.8 4.3e-05 22.7 10.9 4.5 4 0 0 4 4 4 3 Protein of unknown function (DUF2722) GREB1 PF15782.5 CDJ53992.1 - 0.00055 17.2 4.9 0.00055 17.2 4.9 3.2 3 0 0 3 3 3 1 Gene regulated by oestrogen in breast cancer Eapp_C PF10238.9 CDJ53992.1 - 0.0031 17.6 52.7 0.022 14.8 5.8 4.8 4 0 0 4 4 4 2 E2F-associated phosphoprotein EPL1 PF10513.9 CDJ53992.1 - 0.006 17.0 6.8 0.006 17.0 6.8 4.4 3 1 0 4 4 3 1 Enhancer of polycomb-like Otopetrin PF03189.13 CDJ53992.1 - 0.063 12.1 27.5 0.014 14.3 11.0 3.2 3 0 0 3 3 3 0 Otopetrin EIIBC-GUT_N PF03612.14 CDJ53992.1 - 0.26 11.0 55.9 1.3 8.7 6.6 4.5 4 0 0 4 4 4 0 Sorbitol phosphotransferase enzyme II N-terminus FAM176 PF14851.6 CDJ53992.1 - 0.62 9.7 45.9 0.49 10.1 4.2 4.4 4 0 0 4 4 4 0 FAM176 family TERB2 PF15101.6 CDJ53992.1 - 0.74 9.8 77.1 0.57 10.2 16.6 4.5 4 0 0 4 4 4 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CDJ53992.1 - 0.99 9.0 151.1 0.21 11.1 21.7 4.3 4 0 0 4 4 4 0 Spt20 family Na_trans_assoc PF06512.13 CDJ53992.1 - 1.9 8.7 35.2 2.4 8.4 15.1 3.4 3 0 0 3 3 3 0 Sodium ion transport-associated Pinin_SDK_memA PF04696.13 CDJ53992.1 - 4.1 7.5 97.9 1.7 8.7 13.9 4.5 4 0 0 4 4 4 0 pinin/SDK/memA/ protein conserved region CCDC84 PF14968.6 CDJ53992.1 - 5.2 6.6 43.7 0.68 9.5 16.4 3.3 3 0 0 3 3 3 0 Coiled coil protein 84 AAA_23 PF13476.6 CDJ53992.1 - 8.1 6.9 75.5 1.4 9.4 2.8 4.2 4 0 0 4 4 4 0 AAA domain Hist_deacetyl PF00850.19 CDJ53993.1 - 0.73 9.2 5.6 0.8 9.1 5.6 1.0 1 0 0 1 1 1 0 Histone deacetylase domain SLC12 PF03522.15 CDJ53993.1 - 1 8.3 14.4 1.1 8.2 14.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DRY_EERY PF09750.9 CDJ53993.1 - 2.1 8.6 17.3 2.6 8.3 17.3 1.1 1 0 0 1 1 1 0 Alternative splicing regulator Pex14_N PF04695.13 CDJ53993.1 - 2.6 8.7 19.7 4.4 8.0 19.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF740 PF05340.12 CDJ53993.1 - 3.8 6.1 5.2 4.4 5.9 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Band_3_cyto PF07565.13 CDJ53993.1 - 4.1 7.1 13.5 4.2 7.1 13.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ureide_permease PF07168.11 CDJ53993.1 - 4.3 6.0 5.3 5 5.8 5.3 1.1 1 0 0 1 1 1 0 Ureide permease ALMT PF11744.8 CDJ53993.1 - 4.5 6.0 10.4 4.9 5.9 10.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Glyco_transf_41 PF13844.6 CDJ53993.1 - 4.6 5.6 10.7 4.9 5.5 10.7 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 41 CSG2 PF16965.5 CDJ53993.1 - 5.9 5.7 8.1 6.2 5.6 8.1 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator HCO3_cotransp PF00955.21 CDJ53993.1 - 7.4 5.3 5.7 7.7 5.2 5.7 1.0 1 0 0 1 1 1 0 HCO3- transporter family TFIIA PF03153.13 CDJ53994.1 - 0.0042 17.1 29.7 0.0055 16.8 29.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit EOS1 PF12326.8 CDJ53994.1 - 0.15 12.0 0.9 0.18 11.7 0.9 1.3 1 0 0 1 1 1 0 N-glycosylation protein WD40 PF00400.32 CDJ53994.1 - 0.2 12.6 0.1 1.7 9.6 0.0 2.5 3 0 0 3 3 2 0 WD domain, G-beta repeat GAGA_bind PF06217.12 CDJ53994.1 - 0.23 11.7 13.4 0.28 11.4 13.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Med19 PF10278.9 CDJ53994.1 - 0.5 10.3 14.3 0.69 9.8 14.3 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF2052 PF09747.9 CDJ53994.1 - 0.84 9.7 17.3 1.6 8.8 17.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) YjbH PF06082.11 CDJ53994.1 - 0.95 8.2 13.1 1.2 7.9 13.1 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF4342 PF14242.6 CDJ53994.1 - 1.2 9.2 2.8 2.6 8.1 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) DNA_pol3_a_NII PF11490.8 CDJ53994.1 - 2.6 7.9 21.3 6.6 6.7 21.3 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Neur_chan_memb PF02932.16 CDJ53994.1 - 2.8 7.9 8.0 3.8 7.5 8.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TERB2 PF15101.6 CDJ53994.1 - 4.6 7.2 15.7 8.9 6.3 15.7 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 CDJ53994.1 - 5.7 5.6 14.7 7.9 5.1 14.7 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S15 PF02129.18 CDJ53994.1 - 6.6 6.2 11.6 10 5.6 11.6 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) eIF-3_zeta PF05091.12 CDJ53994.1 - 6.6 5.6 16.5 8.9 5.2 16.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PCIF1_WW PF12237.8 CDJ53996.1 - 2.9e-24 85.6 0.2 1.3e-20 73.7 1.3 2.9 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain SPX PF03105.19 CDJ53996.1 - 5.2e-06 26.6 52.5 0.25 11.2 6.0 5.3 4 2 1 5 5 5 2 SPX domain SR-25 PF10500.9 CDJ53996.1 - 0.00011 21.9 11.6 0.00011 21.9 11.6 8.5 7 1 1 8 8 8 3 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 CDJ53996.1 - 0.00071 19.2 26.1 0.00071 19.2 26.1 6.0 6 0 0 6 6 6 2 Ras-mediated vulval-induction antagonist Ribosomal_60s PF00428.19 CDJ53997.1 - 0.024 15.2 6.7 0.045 14.3 6.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Shadoo PF14999.6 CDJ53997.1 - 0.25 11.5 13.0 0.39 10.8 13.0 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PmbA_TldD PF01523.16 CDJ53998.1 - 1.9 8.3 7.6 2.1 8.1 7.6 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase CobT PF06213.12 CDJ53999.1 - 0.00078 18.9 8.8 0.00078 18.9 8.8 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Connexin PF00029.19 CDJ53999.1 - 0.0017 18.1 0.3 0.0017 18.1 0.3 1.2 1 0 0 1 1 1 1 Connexin RskA PF10099.9 CDJ53999.1 - 0.0035 17.7 0.0 0.0058 16.9 0.0 1.4 1 1 0 1 1 1 1 Anti-sigma-K factor rskA EIIBC-GUT_N PF03612.14 CDJ53999.1 - 0.01 15.6 3.0 0.012 15.4 3.0 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SID-1_RNA_chan PF13965.6 CDJ53999.1 - 0.013 13.9 0.1 0.015 13.8 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 CDJ53999.1 - 0.017 14.2 4.1 0.02 14.0 4.1 1.3 1 0 0 1 1 1 0 CLN3 protein eIF-3_zeta PF05091.12 CDJ53999.1 - 0.018 14.0 10.2 0.017 14.1 10.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.17 CDJ53999.1 - 0.023 14.9 4.5 0.023 14.8 4.5 1.1 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 CDJ53999.1 - 0.023 14.7 0.5 0.023 14.7 0.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.6 CDJ53999.1 - 0.086 13.0 5.8 0.1 12.8 5.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peroxin-13_N PF04088.13 CDJ53999.1 - 0.26 11.5 3.0 0.4 10.9 3.0 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4834 PF16118.5 CDJ53999.1 - 0.29 12.1 16.6 0.57 11.2 16.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2828 PF11443.8 CDJ53999.1 - 0.3 9.1 9.2 0.32 9.0 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) GNAT_acetyltr_2 PF13718.6 CDJ53999.1 - 0.63 9.4 7.5 0.83 9.0 7.5 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 TFIIA PF03153.13 CDJ53999.1 - 0.93 9.4 25.5 1 9.2 25.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ53999.1 - 2.7 7.4 13.9 3.2 7.1 13.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pinin_SDK_memA PF04696.13 CDJ53999.1 - 4.8 7.3 31.8 6.5 6.8 31.8 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Spt20 PF12090.8 CDJ53999.1 - 5.1 6.7 33.1 6.6 6.3 33.1 1.2 1 0 0 1 1 1 0 Spt20 family PIP5K PF01504.18 CDJ53999.1 - 5.2 6.2 13.1 7 5.8 13.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Pex14_N PF04695.13 CDJ53999.1 - 6.9 7.3 16.7 12 6.6 16.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_2 PF07719.17 CDJ54002.1 - 0.004 17.2 2.7 3.2 8.1 0.6 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat SF-assemblin PF06705.11 CDJ54003.1 - 4.7e-24 85.1 13.2 1.6e-09 37.5 0.1 3.0 2 1 1 3 3 3 3 SF-assemblin/beta giardin ApoLp-III PF07464.11 CDJ54003.1 - 0.013 15.5 1.0 5.3 7.1 0.0 2.4 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) HMMR_N PF15905.5 CDJ54003.1 - 0.019 14.5 2.8 0.029 13.8 2.8 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal SHE3 PF17078.5 CDJ54003.1 - 0.037 13.8 0.2 0.066 12.9 0.2 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Exonuc_VII_L PF02601.15 CDJ54003.1 - 0.35 10.4 6.5 0.71 9.4 6.5 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit FlaC_arch PF05377.11 CDJ54003.1 - 0.72 10.3 2.3 3.7 8.0 0.5 2.9 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) PvlArgDC PF01862.16 CDJ54003.1 - 1.9 8.3 6.5 17 5.2 6.4 2.5 1 1 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) DASH_Spc19 PF08287.11 CDJ54003.1 - 8.4 6.3 11.7 0.73 9.7 2.8 3.1 2 1 1 3 3 3 0 Spc19 TniQ PF06527.11 CDJ54004.1 - 0.055 14.2 0.4 0.055 14.2 0.4 4.3 5 0 0 5 5 5 0 TniQ Fn3_assoc PF13287.6 CDJ54004.1 - 0.15 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 Fn3 associated DDHD PF02862.17 CDJ54004.1 - 1.2 9.2 22.5 3 8.0 2.5 4.3 4 0 0 4 4 4 0 DDHD domain IMUP PF15761.5 CDJ54006.1 - 0.5 11.1 7.6 1.4 9.6 1.5 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein Dehydrin PF00257.19 CDJ54006.1 - 9.8 6.7 7.0 2.1 8.9 0.6 2.2 2 0 0 2 2 2 0 Dehydrin FANCL_C PF11793.8 CDJ54007.1 - 0.2 11.9 0.5 0.65 10.2 0.1 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain CODH_A_N PF18537.1 CDJ54008.1 - 0.45 10.5 3.0 1.7 8.7 0.0 3.1 3 0 0 3 3 3 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Trimer_CC PF08954.11 CDJ54008.1 - 6.4 6.4 7.0 36 4.0 2.5 2.9 1 1 1 2 2 2 0 Trimerisation motif Thioredoxin PF00085.20 CDJ54010.1 - 8e-08 32.2 0.0 0.00093 19.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 CDJ54010.1 - 0.00067 19.1 0.0 0.99 8.7 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 CDJ54010.1 - 0.0011 18.9 0.0 0.078 13.0 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.6 CDJ54010.1 - 0.0028 18.1 0.0 0.012 16.0 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain PhyH PF05721.13 CDJ54011.1 - 1.2e-13 51.8 0.0 1.4e-12 48.3 0.0 2.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SBD_N PF07005.11 CDJ54011.1 - 0.029 14.1 0.3 1.6 8.4 0.2 2.9 2 1 0 3 3 3 0 Sugar-binding N-terminal domain TauD PF02668.16 CDJ54011.1 - 0.032 14.0 0.0 0.13 12.1 0.0 1.9 2 1 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family rve PF00665.26 CDJ54014.1 - 4.3e-07 30.2 0.1 8.1e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain Vps39_1 PF10366.9 CDJ54014.1 - 0.2 12.0 2.5 0.48 10.7 2.5 1.8 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Med15 PF09606.10 CDJ54015.1 - 1.9 7.1 68.2 2.7 6.5 68.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Adaptin_N PF01602.20 CDJ54016.1 - 1e-21 77.1 0.0 1.2e-18 66.9 0.0 2.4 2 1 0 2 2 2 2 Adaptin N terminal region DUF2811 PF10929.8 CDJ54016.1 - 0.097 13.0 0.5 0.23 11.8 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) RskA PF10099.9 CDJ54017.1 - 0.0012 19.2 8.9 0.005 17.2 3.9 2.0 1 1 1 2 2 2 2 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ54017.1 - 0.01 16.3 0.1 0.028 14.9 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) SARAF PF06682.12 CDJ54017.1 - 0.011 15.4 7.6 0.014 15.1 7.6 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Spt20 PF12090.8 CDJ54017.1 - 0.03 14.0 21.8 0.045 13.4 21.8 1.3 1 0 0 1 1 1 0 Spt20 family ETRAMP PF09716.10 CDJ54017.1 - 0.082 13.0 1.4 4.3 7.5 0.9 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FHIPEP PF00771.20 CDJ54017.1 - 0.083 11.4 5.3 0.091 11.2 5.3 1.1 1 0 0 1 1 1 0 FHIPEP family CTNNB1_binding PF08347.11 CDJ54017.1 - 0.092 12.9 5.1 0.13 12.4 5.1 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Velvet PF11754.8 CDJ54017.1 - 0.1 12.5 8.8 0.11 12.5 8.8 1.1 1 0 0 1 1 1 0 Velvet factor DUF4366 PF14283.6 CDJ54017.1 - 0.13 12.3 2.5 0.31 11.1 2.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) NVEALA PF14055.6 CDJ54017.1 - 0.16 12.0 5.7 0.47 10.5 0.1 3.5 1 1 3 4 4 4 0 NVEALA protein TFIIA PF03153.13 CDJ54017.1 - 0.18 11.8 26.5 0.21 11.6 26.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit R_equi_Vir PF05526.11 CDJ54017.1 - 0.24 11.2 5.3 0.34 10.7 5.3 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF2700 PF10912.8 CDJ54017.1 - 0.25 11.3 0.1 0.42 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) SR-25 PF10500.9 CDJ54017.1 - 0.28 10.8 16.9 0.3 10.7 16.0 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CrgA PF06781.12 CDJ54017.1 - 0.29 11.2 0.9 0.65 10.1 0.1 2.0 2 0 0 2 2 2 0 Cell division protein CrgA MCM_bind PF09739.9 CDJ54017.1 - 0.37 9.2 10.0 0.47 8.8 10.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor MAPEG PF01124.18 CDJ54017.1 - 0.63 9.9 4.5 6.5 6.7 5.4 1.9 1 1 1 2 2 2 0 MAPEG family Presenilin PF01080.17 CDJ54017.1 - 0.72 8.6 11.8 0.79 8.4 11.8 1.1 1 0 0 1 1 1 0 Presenilin Sox_N PF12444.8 CDJ54017.1 - 0.79 10.9 6.3 1.7 9.8 6.3 1.5 1 0 0 1 1 1 0 Sox developmental protein N terminal DUF1345 PF07077.11 CDJ54017.1 - 0.94 9.2 4.1 9.9 5.8 4.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1345) DUF5336 PF17270.2 CDJ54017.1 - 1.5 8.5 9.2 0.48 10.0 5.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5336) Ctr PF04145.15 CDJ54017.1 - 1.7 9.3 8.8 3.5 8.2 8.8 1.6 1 1 0 1 1 1 0 Ctr copper transporter family Band_3_cyto PF07565.13 CDJ54017.1 - 2.2 8.0 9.3 2.5 7.8 9.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Rpp20 PF12328.8 CDJ54017.1 - 2.2 8.2 10.3 1.6 8.7 8.5 1.6 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF588 PF04535.12 CDJ54017.1 - 3.6 7.3 7.4 44 3.8 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF588) Neur_chan_memb PF02932.16 CDJ54017.1 - 4.7 7.2 10.3 5.3 7.0 10.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ54017.1 - 9.3 4.9 12.7 9.9 4.9 12.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RskA PF10099.9 CDJ54019.1 - 1.6 9.0 23.8 2.4 8.4 23.8 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Velvet PF11754.8 CDJ54019.1 - 2.5 7.9 9.9 2.6 7.9 9.9 1.0 1 0 0 1 1 1 0 Velvet factor Presenilin PF01080.17 CDJ54019.1 - 5.3 5.7 14.4 5.1 5.7 14.4 1.0 1 0 0 1 1 1 0 Presenilin DUF3450 PF11932.8 CDJ54019.1 - 5.7 6.2 21.7 6.9 5.9 21.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HemX PF04375.14 CDJ54019.1 - 6.2 6.0 22.9 7.2 5.8 22.9 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase MAJIN PF15077.6 CDJ54019.1 - 9.5 5.9 10.9 10 5.8 10.9 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4228 PF14009.6 CDJ54019.1 - 9.8 6.5 13.7 13 6.1 13.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Herpes_BLLF1 PF05109.13 CDJ54021.1 - 0.44 8.5 8.4 0.58 8.1 8.4 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Spc29 PF17082.5 CDJ54021.1 - 1.3 8.9 10.9 7.5 6.3 8.7 2.3 2 0 0 2 2 2 0 Spindle Pole Component 29 V_ATPase_I PF01496.19 CDJ54021.1 - 3.6 5.4 11.6 2.6 5.9 10.0 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TPR_1 PF00515.28 CDJ54022.1 - 7e-11 41.5 0.1 9.5e-09 34.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ54022.1 - 1.3e-09 37.5 0.1 1.3e-06 28.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ54022.1 - 1.3e-08 35.0 0.1 1.1e-05 25.6 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ54022.1 - 2.1e-08 33.7 0.9 1.8e-05 24.5 0.0 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ54022.1 - 4e-08 32.7 0.4 0.012 15.6 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat GFO_IDH_MocA PF01408.22 CDJ54022.1 - 1.9e-07 31.9 0.0 5.2e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TPR_14 PF13428.6 CDJ54022.1 - 3.6e-05 24.2 0.8 0.11 13.4 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ54022.1 - 7.5e-05 22.3 0.1 0.0081 15.8 0.2 2.6 1 1 1 2 2 2 1 TPR repeat TPR_19 PF14559.6 CDJ54022.1 - 0.0004 20.8 0.2 0.0016 18.9 0.2 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ54022.1 - 0.00052 20.6 0.0 0.0021 18.7 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat Methyltransf_28 PF02636.17 CDJ54022.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AMA-1 PF02430.15 CDJ54023.1 - 4e-41 141.5 0.0 4.1e-26 92.0 0.0 2.5 1 1 2 3 3 3 2 Apical membrane antigen 1 FAM176 PF14851.6 CDJ54023.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 FAM176 family FAP206 PF12018.8 CDJ54024.1 - 7.5e-08 32.2 0.0 1.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function YHS PF04945.13 CDJ54024.1 - 3e-05 24.0 0.1 0.0026 17.8 0.0 2.4 2 0 0 2 2 2 1 YHS domain TraC PF07820.12 CDJ54024.1 - 0.26 11.6 3.4 0.83 10.0 3.4 1.8 1 0 0 1 1 1 0 TraC-like protein NPR3 PF03666.13 CDJ54025.1 - 0.098 11.4 14.4 0.11 11.3 14.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 CDJ54025.1 - 0.25 10.1 13.3 0.29 9.9 13.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hydin_ADK PF17213.3 CDJ54025.1 - 0.26 11.6 12.2 0.36 11.1 12.2 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RR_TM4-6 PF06459.12 CDJ54025.1 - 0.37 10.6 21.4 0.43 10.3 21.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.15 CDJ54025.1 - 0.51 9.9 20.3 0.55 9.7 20.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop53 PF07767.11 CDJ54025.1 - 0.72 9.2 27.9 0.83 9.0 27.9 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SLC12 PF03522.15 CDJ54025.1 - 0.74 8.8 19.4 0.88 8.5 19.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CLN3 PF02487.17 CDJ54025.1 - 1.1 8.3 16.0 1.3 8.0 16.0 1.0 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 CDJ54025.1 - 1.1 7.9 23.7 1.4 7.6 23.7 1.0 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CDJ54025.1 - 1.2 8.3 10.8 1.4 8.1 10.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 CDJ54025.1 - 1.4 8.4 18.5 1.7 8.1 18.5 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 PAT1 PF09770.9 CDJ54025.1 - 1.4 7.1 34.5 1.4 7.1 34.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Plasmodium_Vir PF05795.11 CDJ54025.1 - 1.6 8.1 7.0 1.6 8.1 7.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_S64 PF08192.11 CDJ54025.1 - 1.7 7.1 14.6 2 6.8 14.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2828 PF11443.8 CDJ54025.1 - 1.7 6.6 19.6 1.9 6.4 19.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) eIF-3_zeta PF05091.12 CDJ54025.1 - 1.8 7.4 24.5 2.2 7.1 24.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MAJIN PF15077.6 CDJ54025.1 - 1.8 8.3 14.5 2 8.1 14.5 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein PA26 PF04636.13 CDJ54025.1 - 1.9 7.3 16.2 2.2 7.1 16.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.7 CDJ54025.1 - 2.4 6.2 18.7 2.9 5.9 18.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rrn6 PF10214.9 CDJ54025.1 - 2.8 6.3 24.0 2.7 6.4 24.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SpoIIP PF07454.11 CDJ54025.1 - 2.9 7.3 18.8 4.9 6.5 18.8 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4746 PF15928.5 CDJ54025.1 - 3 7.2 12.6 4.1 6.7 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ALMT PF11744.8 CDJ54025.1 - 3 6.6 16.3 3.2 6.5 16.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM60A PF15396.6 CDJ54025.1 - 3 7.8 15.9 3.8 7.5 15.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A NARP1 PF12569.8 CDJ54025.1 - 4.4 6.1 17.8 5.6 5.8 17.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Scs3p PF10261.9 CDJ54025.1 - 4.5 6.7 5.8 6.5 6.2 5.8 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM MDM10 PF12519.8 CDJ54025.1 - 4.6 6.0 17.6 5.6 5.7 17.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Endostatin PF06482.11 CDJ54025.1 - 4.6 6.6 22.3 5.3 6.4 22.3 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF913 PF06025.12 CDJ54025.1 - 5.1 6.0 11.1 6.1 5.7 11.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BORG_CEP PF14957.6 CDJ54025.1 - 5.2 8.3 13.4 6.3 8.0 13.4 1.2 1 0 0 1 1 1 0 Cdc42 effector Rtf2 PF04641.12 CDJ54025.1 - 5.4 6.3 18.3 6.6 6.0 18.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger V_ATPase_I PF01496.19 CDJ54025.1 - 5.4 4.8 23.9 6.4 4.6 23.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LAP1C PF05609.12 CDJ54025.1 - 5.6 5.9 21.4 6.6 5.7 21.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Gti1_Pac2 PF09729.9 CDJ54025.1 - 5.6 7.0 16.8 7.2 6.7 16.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4569 PF15133.6 CDJ54025.1 - 6.1 6.5 20.9 7.3 6.2 20.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Membralin PF09746.9 CDJ54025.1 - 8.4 5.3 12.3 9.8 5.1 12.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein FliP PF00813.20 CDJ54025.1 - 8.4 6.2 11.8 10 5.9 11.8 1.1 1 0 0 1 1 1 0 FliP family Neur_chan_memb PF02932.16 CDJ54025.1 - 9.3 6.2 17.4 10 6.1 17.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CSG2 PF16965.5 CDJ54025.1 - 9.9 5.0 11.0 13 4.6 11.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Arm PF00514.23 CDJ54027.1 - 4.2e-15 55.2 7.7 5.9e-05 23.0 0.0 6.6 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDJ54027.1 - 8.4e-13 48.5 9.4 5.1e-06 26.8 0.5 4.7 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 CDJ54027.1 - 2e-08 33.8 4.2 0.00055 20.0 0.0 6.1 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 CDJ54027.1 - 4e-08 33.5 0.0 0.00024 21.2 0.0 2.9 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CDJ54027.1 - 3.4e-05 22.6 0.7 0.32 9.5 0.1 4.0 2 1 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.8 CDJ54027.1 - 0.0015 18.1 0.2 0.0055 16.3 0.1 1.9 2 0 0 2 2 2 1 CLASP N terminal HEAT_EZ PF13513.6 CDJ54027.1 - 0.0076 16.7 15.0 0.53 10.8 0.1 5.6 5 2 2 7 7 7 2 HEAT-like repeat LIP PF03583.14 CDJ54027.1 - 0.086 12.1 0.3 16 4.7 0.0 2.5 2 1 0 2 2 2 0 Secretory lipase PhoU PF01895.19 CDJ54027.1 - 0.15 12.5 0.1 3.1 8.3 0.0 2.9 3 1 1 4 4 4 0 PhoU domain Vac14_Fab1_bd PF12755.7 CDJ54027.1 - 0.17 12.5 0.1 6.8 7.4 0.0 3.1 2 2 2 4 4 4 0 Vacuolar 14 Fab1-binding region SR-25 PF10500.9 CDJ54028.1 - 0.0056 16.3 13.2 0.0056 16.3 13.2 4.8 3 1 1 5 5 5 1 Nuclear RNA-splicing-associated protein DIE2_ALG10 PF04922.12 CDJ54028.1 - 0.16 11.2 1.1 0.34 10.1 1.1 1.5 1 0 0 1 1 1 0 DIE2/ALG10 family TFIIA PF03153.13 CDJ54029.1 - 0.15 12.0 13.4 0.18 11.8 13.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP1 PF08601.10 CDJ54029.1 - 0.65 9.7 21.1 0.79 9.4 21.1 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 CDJ54029.1 - 0.86 8.1 13.3 1.3 7.5 13.3 1.3 1 0 0 1 1 1 0 Macoilin family DUF2868 PF11067.8 CDJ54029.1 - 0.96 8.9 9.8 1.2 8.6 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) PA26 PF04636.13 CDJ54029.1 - 1 8.2 4.9 1.2 8.0 4.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 CDJ54029.1 - 1.7 7.3 10.6 2.1 7.0 10.6 1.3 1 0 0 1 1 1 0 Presenilin SARAF PF06682.12 CDJ54029.1 - 2.9 7.5 15.7 3.7 7.1 15.7 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis BAF1_ABF1 PF04684.13 CDJ54029.1 - 4.1 6.3 12.4 5.2 6.0 12.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Sin_N PF04801.13 CDJ54029.1 - 5.7 6.0 13.3 6.4 5.9 13.3 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region Miga PF10265.9 CDJ54029.1 - 9.8 5.0 9.2 11 4.8 9.2 1.1 1 0 0 1 1 1 0 Mitoguardin SR-25 PF10500.9 CDJ54030.1 - 2.4 7.7 6.7 4.6 6.8 6.7 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATP11 PF06644.11 CDJ54031.1 - 0.092 12.5 20.5 0.1 12.4 20.5 1.0 1 0 0 1 1 1 0 ATP11 protein DUF4228 PF14009.6 CDJ54031.1 - 0.6 10.5 9.2 0.64 10.4 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) SDP_N PF12278.8 CDJ54031.1 - 0.69 10.1 21.0 0.9 9.7 21.0 1.3 1 0 0 1 1 1 0 Sex determination protein N terminal Connexin PF00029.19 CDJ54031.1 - 1.1 9.0 15.9 1.3 8.7 15.9 1.2 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 CDJ54031.1 - 1.2 8.9 24.4 1.4 8.7 24.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MMU163 PF17119.5 CDJ54031.1 - 1.3 8.2 9.9 1.3 8.1 9.9 1.0 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Pex14_N PF04695.13 CDJ54031.1 - 1.3 9.6 28.0 1.7 9.3 28.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3504 PF12012.8 CDJ54031.1 - 1.5 8.7 16.6 1.6 8.6 16.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) EPL1 PF10513.9 CDJ54031.1 - 1.5 9.2 20.2 1.9 8.8 20.2 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like ORC5_C PF14630.6 CDJ54031.1 - 1.7 8.1 10.4 2.3 7.7 10.4 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus OATP PF03137.20 CDJ54031.1 - 1.7 6.8 12.5 1.9 6.7 12.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAM60A PF15396.6 CDJ54031.1 - 1.7 8.6 17.5 1.7 8.6 17.5 1.0 1 0 0 1 1 1 0 Protein Family FAM60A PIP5K PF01504.18 CDJ54031.1 - 1.8 7.7 14.9 2.1 7.5 14.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Gti1_Pac2 PF09729.9 CDJ54031.1 - 1.9 8.6 15.5 2 8.5 15.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family baeRF_family12 PF18856.1 CDJ54031.1 - 2.2 8.9 15.3 2.9 8.5 15.3 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 DDHD PF02862.17 CDJ54031.1 - 2.5 8.2 17.3 2.7 8.1 17.3 1.1 1 0 0 1 1 1 0 DDHD domain SpoIIP PF07454.11 CDJ54031.1 - 2.5 7.5 21.3 2.8 7.3 21.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CSG2 PF16965.5 CDJ54031.1 - 2.8 6.8 12.7 2.9 6.8 12.7 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator CLN3 PF02487.17 CDJ54031.1 - 2.8 6.9 18.9 3.1 6.8 18.9 1.0 1 0 0 1 1 1 0 CLN3 protein DUF913 PF06025.12 CDJ54031.1 - 3 6.7 12.4 3.4 6.6 12.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Kei1 PF08552.11 CDJ54031.1 - 3.5 7.5 11.5 4.6 7.1 11.5 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Zip PF02535.22 CDJ54031.1 - 3.8 6.6 13.7 4 6.5 13.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 CDJ54031.1 - 3.9 6.9 18.3 4.4 6.8 18.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CCDC53 PF10152.9 CDJ54031.1 - 5.3 7.4 21.1 7.3 7.0 21.1 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex NPR3 PF03666.13 CDJ54031.1 - 5.4 5.7 19.3 5.8 5.6 19.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MDM31_MDM32 PF08118.11 CDJ54031.1 - 6.2 5.4 15.7 6.3 5.4 15.7 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins HCO3_cotransp PF00955.21 CDJ54031.1 - 6.2 5.5 11.2 6.5 5.4 11.2 1.0 1 0 0 1 1 1 0 HCO3- transporter family Scs3p PF10261.9 CDJ54031.1 - 6.8 6.1 8.5 8 5.9 8.5 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Folliculin PF11704.8 CDJ54031.1 - 7.1 6.5 15.9 7.9 6.3 15.9 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport SLC12 PF03522.15 CDJ54031.1 - 7.6 5.4 23.4 8.3 5.3 23.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ54031.1 - 8.1 6.4 18.5 8.5 6.4 18.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MTABC_N PF16185.5 CDJ54031.1 - 8.5 5.8 16.4 34 3.8 16.4 1.8 1 1 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region Otopetrin PF03189.13 CDJ54031.1 - 9.1 5.0 13.0 9.5 4.9 13.0 1.0 1 0 0 1 1 1 0 Otopetrin DUF2370 PF10176.9 CDJ54031.1 - 9.4 5.8 10.7 10 5.7 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) SNF2_N PF00176.23 CDJ54033.1 - 4.5e-69 232.8 0.0 6.8e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.25 CDJ54033.1 - 9.2e-08 31.8 5.7 2e-07 30.8 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ54033.1 - 1.1e-07 31.7 3.6 2.5e-07 30.5 3.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDJ54033.1 - 5.3e-07 29.4 4.9 1e-06 28.5 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ54033.1 - 2.1e-06 28.0 5.7 5e-06 26.7 5.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ54033.1 - 2.1e-06 27.5 6.2 4.8e-06 26.3 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ54033.1 - 4.8e-05 23.3 2.9 0.00014 21.8 2.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Helicase_C PF00271.31 CDJ54033.1 - 0.0023 18.2 0.0 0.048 14.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.6 CDJ54033.1 - 0.0026 17.9 7.1 0.0065 16.6 7.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDJ54033.1 - 0.0072 16.2 7.2 0.021 14.7 7.3 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDJ54033.1 - 0.02 14.7 1.9 0.049 13.4 1.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CDJ54033.1 - 0.022 14.8 2.4 0.044 13.8 2.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 CDJ54033.1 - 0.13 12.5 0.1 0.54 10.6 0.1 2.1 1 0 0 1 1 1 0 zinc-ribbon zf-C3HC4_5 PF17121.5 CDJ54033.1 - 6.1 6.8 5.9 18 5.3 5.5 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Leu_Phe_trans PF03588.14 CDJ54035.1 - 7.4e-12 45.1 0.2 2.1e-09 37.2 0.0 2.7 3 0 0 3 3 3 2 Leucyl/phenylalanyl-tRNA protein transferase zf-B_box PF00643.24 CDJ54036.1 - 1.7e-10 40.8 16.6 1.2e-05 25.3 6.5 2.7 3 0 0 3 3 3 2 B-box zinc finger DUF3135 PF11333.8 CDJ54036.1 - 0.0036 17.5 0.7 0.01 16.0 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3135) PARP PF00644.20 CDJ54036.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain FAD-oxidase_C PF02913.19 CDJ54037.1 - 1.2e-39 136.5 0.0 1.6e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CDJ54037.1 - 5.6e-34 116.9 0.5 9.1e-34 116.2 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain MIP-T3_C PF17749.1 CDJ54038.1 - 0.0002 21.3 0.3 0.00022 21.2 0.3 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region Fib_alpha PF08702.10 CDJ54038.1 - 0.0033 17.6 0.1 0.0035 17.5 0.1 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family KxDL PF10241.9 CDJ54038.1 - 0.011 16.0 0.6 0.015 15.5 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF3209 PF11483.8 CDJ54038.1 - 0.052 14.0 0.2 0.061 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Methyltransf_15 PF09445.10 CDJ54041.1 - 5.9e-26 91.0 0.0 9.2e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 CDJ54041.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 CDJ54041.1 - 0.00025 21.7 0.2 0.00091 19.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 CDJ54041.1 - 0.0008 19.2 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 CDJ54041.1 - 0.02 15.5 0.0 0.059 14.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CDJ54041.1 - 0.25 10.3 0.0 0.4 9.6 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase RVP_2 PF08284.11 CDJ54045.1 - 6.6e-06 25.9 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDJ54045.1 - 1.1e-05 26.0 0.0 2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ54045.1 - 1.3e-05 25.6 0.0 2.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDJ54045.1 - 0.064 13.6 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 CDJ54046.1 - 1.1e-25 89.9 0.0 2.1e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ54046.1 - 8.8e-23 80.2 0.0 1.6e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ54046.1 - 3.7e-19 69.1 0.0 7.4e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Histone PF00125.24 CDJ54049.1 - 2.8e-17 63.3 0.0 4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CDJ54049.1 - 6e-11 41.9 0.1 1.2e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CDJ54049.1 - 8.2e-05 22.8 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ad_Cy_reg PF16701.5 CDJ54050.1 - 0.053 13.3 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain DUF2213 PF09979.9 CDJ54051.1 - 0.0057 16.7 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2213) Nop53 PF07767.11 CDJ54052.1 - 3.2 7.0 11.7 4.9 6.4 11.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ESSS PF10183.9 CDJ54052.1 - 4.8 7.4 6.2 51 4.2 6.3 2.8 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3824 PF12868.7 CDJ54053.1 - 0.026 15.2 10.1 0.026 15.2 10.1 2.8 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) Coilin_N PF15862.5 CDJ54053.1 - 0.092 12.5 3.7 0.11 12.3 3.7 1.1 1 0 0 1 1 1 0 Coilin N-terminus DZF PF07528.14 CDJ54054.1 - 0.081 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 DZF domain tRNA-synt_1 PF00133.22 CDJ54055.1 - 3.7e-10 38.7 0.0 8e-10 37.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 CDJ54055.1 - 0.03 13.2 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1d PF00750.19 CDJ54055.1 - 0.2 10.5 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (R) TraT PF05818.12 CDJ54055.1 - 0.46 10.1 3.8 0.48 10.1 3.8 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF1645 PF07816.11 CDJ54056.1 - 0.0072 16.9 1.2 0.0072 16.9 1.2 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1645) Secretin_N_2 PF07655.13 CDJ54056.1 - 0.15 12.6 23.8 0.48 11.0 8.6 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Pox_A12 PF04651.13 CDJ54056.1 - 0.94 9.5 14.2 0.2 11.7 2.2 2.3 2 0 0 2 2 2 0 Poxvirus A12 protein SUIM_assoc PF16619.5 CDJ54057.1 - 3.6 7.7 20.1 11 6.2 4.1 3.3 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF5564 PF17719.1 CDJ54057.1 - 7.2 6.8 7.6 0.52 10.5 0.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5564) Rep_fac-A_3 PF08661.11 CDJ54058.1 - 0.00016 21.9 0.6 0.00025 21.4 0.4 1.5 1 1 0 1 1 1 1 Replication factor A protein 3 TFIIA PF03153.13 CDJ54058.1 - 0.0029 17.7 12.9 0.0029 17.7 12.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ54058.1 - 0.0035 16.1 13.9 0.0035 16.1 13.9 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.9 CDJ54058.1 - 0.0037 17.6 1.6 0.0046 17.3 1.6 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ54058.1 - 0.082 13.9 3.3 0.11 13.5 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ54058.1 - 0.11 12.1 24.3 0.13 11.9 24.3 1.1 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ54058.1 - 0.27 11.2 7.2 0.32 10.9 7.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF775 PF05603.12 CDJ54058.1 - 0.4 10.2 6.1 0.55 9.7 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Androgen_recep PF02166.16 CDJ54058.1 - 0.56 9.0 18.6 0.63 8.8 18.6 1.3 1 0 0 1 1 1 0 Androgen receptor Ribosomal_L1 PF00687.21 CDJ54059.1 - 0.0039 17.0 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Dehydratase_MU PF02288.15 CDJ54059.1 - 0.01 15.7 1.8 0.01 15.7 1.8 2.9 2 1 1 3 3 3 0 Dehydratase medium subunit FRQ PF09421.10 CDJ54059.1 - 0.045 11.8 1.9 0.069 11.2 1.9 1.2 1 0 0 1 1 1 0 Frequency clock protein Joubert PF15392.6 CDJ54059.1 - 5.1 6.7 7.9 7 6.3 7.9 1.1 1 0 0 1 1 1 0 Joubert syndrome-associated Chromo PF00385.24 CDJ54060.1 - 9.9e-11 41.4 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FAM91_C PF14648.6 CDJ54061.1 - 0.0065 15.4 3.7 0.0069 15.3 3.7 1.0 1 0 0 1 1 1 1 FAM91 C-terminus DUF5523 PF17661.1 CDJ54061.1 - 0.0081 15.9 9.0 0.0082 15.9 9.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5523) Pex14_N PF04695.13 CDJ54061.1 - 0.011 16.4 26.8 0.014 16.0 26.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ54061.1 - 0.012 15.6 17.4 0.017 15.1 17.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Connexin PF00029.19 CDJ54061.1 - 0.017 14.9 6.6 0.02 14.7 6.6 1.1 1 0 0 1 1 1 0 Connexin SpoIIP PF07454.11 CDJ54061.1 - 0.017 14.6 11.2 0.018 14.5 11.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2207 PF09972.9 CDJ54061.1 - 0.022 13.5 0.4 0.027 13.2 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rxt3 PF08642.10 CDJ54061.1 - 0.024 15.4 3.0 0.029 15.2 3.0 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 CLN3 PF02487.17 CDJ54061.1 - 0.029 13.4 6.9 0.031 13.3 6.9 1.1 1 0 0 1 1 1 0 CLN3 protein PIP5K PF01504.18 CDJ54061.1 - 0.029 13.6 6.0 0.033 13.4 6.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase ArsP_2 PF11449.8 CDJ54061.1 - 0.038 13.2 3.1 0.044 13.0 3.1 1.0 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter DUF2232 PF09991.9 CDJ54061.1 - 0.042 13.0 7.2 0.05 12.8 7.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Lin-8 PF03353.15 CDJ54061.1 - 0.043 13.4 13.4 0.044 13.3 13.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CD20 PF04103.15 CDJ54061.1 - 0.05 13.7 0.0 0.059 13.5 0.0 1.1 1 0 0 1 1 1 0 CD20-like family HCO3_cotransp PF00955.21 CDJ54061.1 - 0.055 12.3 2.9 0.053 12.3 2.9 1.0 1 0 0 1 1 1 0 HCO3- transporter family SID-1_RNA_chan PF13965.6 CDJ54061.1 - 0.056 11.9 4.6 0.057 11.8 4.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CSG2 PF16965.5 CDJ54061.1 - 0.059 12.3 3.7 0.077 11.9 3.7 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2126 PF09899.9 CDJ54061.1 - 0.068 11.3 7.3 0.071 11.2 7.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF913 PF06025.12 CDJ54061.1 - 0.085 11.8 7.4 0.096 11.6 7.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3402 PF11882.8 CDJ54061.1 - 0.11 11.6 9.9 0.12 11.4 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) 7tm_1 PF00001.21 CDJ54061.1 - 0.11 11.8 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DDHD PF02862.17 CDJ54061.1 - 0.13 12.4 13.2 0.14 12.3 13.2 1.1 1 0 0 1 1 1 0 DDHD domain Helicase_RecD PF05127.14 CDJ54061.1 - 0.15 11.9 11.0 0.18 11.6 11.0 1.0 1 0 0 1 1 1 0 Helicase TERB2 PF15101.6 CDJ54061.1 - 0.16 12.0 19.9 0.2 11.7 19.9 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FHIPEP PF00771.20 CDJ54061.1 - 0.17 10.3 13.1 0.19 10.2 13.1 1.0 1 0 0 1 1 1 0 FHIPEP family Ureide_permease PF07168.11 CDJ54061.1 - 0.17 10.6 5.7 0.21 10.3 5.7 1.1 1 0 0 1 1 1 0 Ureide permease PGA_cap PF09587.10 CDJ54061.1 - 0.18 11.2 6.7 0.21 11.0 6.7 1.1 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DUF3408 PF11888.8 CDJ54061.1 - 0.18 11.9 14.0 0.22 11.7 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Scs3p PF10261.9 CDJ54061.1 - 0.21 11.1 3.3 0.24 10.9 3.3 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM XRN_N PF03159.18 CDJ54061.1 - 0.23 10.9 8.5 0.26 10.7 8.5 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DUF4400 PF14348.6 CDJ54061.1 - 0.23 10.9 8.1 0.29 10.6 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) RR_TM4-6 PF06459.12 CDJ54061.1 - 0.24 11.2 15.0 0.26 11.1 15.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF719 PF05334.13 CDJ54061.1 - 0.24 11.6 13.9 0.29 11.3 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) CDC45 PF02724.14 CDJ54061.1 - 0.25 9.6 9.0 0.27 9.5 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Band_3_cyto PF07565.13 CDJ54061.1 - 0.28 11.0 12.1 0.31 10.8 12.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Zip PF02535.22 CDJ54061.1 - 0.29 10.3 5.0 0.35 10.0 5.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ctr PF04145.15 CDJ54061.1 - 0.3 11.7 7.5 0.36 11.4 7.5 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Peptidase_U57 PF05582.12 CDJ54061.1 - 0.31 10.3 8.4 0.34 10.1 8.4 1.1 1 0 0 1 1 1 0 YabG peptidase U57 RICTOR_N PF14664.6 CDJ54061.1 - 0.31 10.0 5.9 0.37 9.7 5.9 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term VIT1 PF01988.19 CDJ54061.1 - 0.35 10.7 8.5 0.47 10.3 8.5 1.2 1 0 0 1 1 1 0 VIT family Folate_carrier PF01770.18 CDJ54061.1 - 0.37 9.5 5.2 0.45 9.2 5.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier Serinc PF03348.15 CDJ54061.1 - 0.37 9.7 9.8 0.41 9.5 9.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peptidase_S49_N PF08496.10 CDJ54061.1 - 0.43 10.6 13.3 0.56 10.2 13.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SMYLE_N PF18615.1 CDJ54061.1 - 0.44 10.1 10.8 0.53 9.8 10.8 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF1980 PF09323.10 CDJ54061.1 - 0.48 10.3 11.1 0.56 10.1 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Activator_LAG-3 PF11498.8 CDJ54061.1 - 0.49 9.3 45.4 0.57 9.1 45.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Eapp_C PF10238.9 CDJ54061.1 - 0.52 10.4 14.2 0.62 10.1 14.2 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Glt_symporter PF03616.14 CDJ54061.1 - 0.59 8.8 4.7 0.7 8.5 4.7 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter RPN2_C PF18004.1 CDJ54061.1 - 0.62 10.0 17.6 0.73 9.7 17.6 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain OATP PF03137.20 CDJ54061.1 - 0.62 8.3 5.8 0.7 8.1 5.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Bul1_N PF04425.12 CDJ54061.1 - 0.76 8.5 9.4 0.83 8.3 9.4 1.1 1 0 0 1 1 1 0 Bul1 N terminus FAM176 PF14851.6 CDJ54061.1 - 0.77 9.4 7.0 1 9.0 7.0 1.2 1 0 0 1 1 1 0 FAM176 family Endostatin PF06482.11 CDJ54061.1 - 0.78 9.1 15.8 0.82 9.1 15.8 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Membralin PF09746.9 CDJ54061.1 - 0.82 8.6 6.6 0.83 8.6 6.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein LAP1C PF05609.12 CDJ54061.1 - 0.93 8.5 16.8 1 8.4 16.8 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Bac_luciferase PF00296.20 CDJ54061.1 - 0.94 8.8 12.9 1.1 8.6 12.9 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase MecA PF05389.12 CDJ54061.1 - 0.94 9.1 10.1 1.1 8.8 10.1 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Neur_chan_memb PF02932.16 CDJ54061.1 - 0.94 9.5 10.2 0.97 9.4 10.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region O-antigen_lig PF13425.6 CDJ54061.1 - 0.95 8.2 4.4 1 8.1 4.4 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CNDH2_C PF16858.5 CDJ54061.1 - 0.96 9.3 17.6 1.1 9.0 17.6 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term EPL1 PF10513.9 CDJ54061.1 - 1.1 9.6 14.0 1.4 9.3 14.0 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like 2HCT PF03390.15 CDJ54061.1 - 1.2 7.7 5.4 1.6 7.3 5.4 1.3 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Trp_oprn_chp PF09534.10 CDJ54061.1 - 1.2 8.9 17.2 2 8.2 17.2 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Paf1 PF03985.13 CDJ54061.1 - 1.3 8.0 14.5 1.4 7.9 14.5 1.1 1 0 0 1 1 1 0 Paf1 R_equi_Vir PF05526.11 CDJ54061.1 - 1.3 8.9 15.6 1.5 8.6 15.6 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Gti1_Pac2 PF09729.9 CDJ54061.1 - 1.4 9.0 10.6 1.5 8.8 10.6 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family V_ATPase_I PF01496.19 CDJ54061.1 - 1.6 6.6 14.3 1.6 6.5 14.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.6 CDJ54061.1 - 1.7 8.6 12.9 1.8 8.5 12.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF3675 PF12428.8 CDJ54061.1 - 1.7 9.2 5.5 2.1 9.0 4.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3675) Sec62 PF03839.16 CDJ54061.1 - 1.7 8.1 10.4 1.9 7.9 10.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 BNR_3 PF13859.6 CDJ54061.1 - 1.8 7.8 7.4 2.2 7.5 7.4 1.1 1 0 0 1 1 1 0 BNR repeat-like domain ABC2_membrane_3 PF12698.7 CDJ54061.1 - 1.8 7.6 6.6 2.1 7.4 6.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein MDM31_MDM32 PF08118.11 CDJ54061.1 - 1.9 7.1 10.8 2.1 6.9 10.8 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins FAM222A PF15258.6 CDJ54061.1 - 2 7.4 27.2 2.1 7.3 27.2 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Tim54 PF11711.8 CDJ54061.1 - 2.2 7.0 14.4 2.5 6.8 14.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF572 PF04502.13 CDJ54061.1 - 2.3 7.8 15.4 2.4 7.7 15.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) EOS1 PF12326.8 CDJ54061.1 - 2.3 8.1 8.2 2.7 7.9 8.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein eIF-3_zeta PF05091.12 CDJ54061.1 - 2.4 7.0 22.1 2.6 6.9 22.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.10 CDJ54061.1 - 2.5 6.7 16.1 2.7 6.6 16.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cellulose_synt PF03552.14 CDJ54061.1 - 2.6 6.4 5.0 2.8 6.3 5.0 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF2828 PF11443.8 CDJ54061.1 - 2.9 5.9 14.6 3.2 5.7 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) ALMT PF11744.8 CDJ54061.1 - 3 6.6 11.2 3.1 6.5 11.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter 60KD_IMP PF02096.20 CDJ54061.1 - 3.1 7.7 15.6 4.5 7.2 15.6 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein EMC3_TMCO1 PF01956.16 CDJ54061.1 - 3.1 7.5 13.0 3.6 7.3 13.0 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Orf78 PF06024.12 CDJ54061.1 - 3.2 8.1 11.5 9.4 6.6 11.5 1.8 1 1 0 1 1 1 0 Orf78 (ac78) Pannexin_like PF12534.8 CDJ54061.1 - 3.3 6.7 11.0 3.7 6.5 11.0 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 PigN PF04987.14 CDJ54061.1 - 3.3 6.5 6.5 3.8 6.2 6.5 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF4569 PF15133.6 CDJ54061.1 - 3.4 7.3 18.0 3.7 7.2 18.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) NEMP PF10225.9 CDJ54061.1 - 3.9 7.1 5.2 4.4 6.9 5.2 1.2 1 0 0 1 1 1 0 NEMP family Baculo_PP31 PF05311.11 CDJ54061.1 - 3.9 6.9 15.7 4.2 6.8 15.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SLC12 PF03522.15 CDJ54061.1 - 4.1 6.3 16.3 4.3 6.3 16.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ54061.1 - 4.2 6.0 22.6 4.6 5.9 22.6 1.0 1 0 0 1 1 1 0 Presenilin YABBY PF04690.13 CDJ54061.1 - 4.5 7.8 11.2 5.5 7.5 11.2 1.2 1 0 0 1 1 1 0 YABBY protein IHABP4_N PF16174.5 CDJ54061.1 - 4.5 7.8 25.6 7.5 7.1 25.6 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4638 PF15472.6 CDJ54061.1 - 4.6 6.9 12.6 5.4 6.7 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF4746 PF15928.5 CDJ54061.1 - 5 6.5 10.5 5.4 6.3 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Peptidase_S15 PF02129.18 CDJ54061.1 - 5.3 6.5 18.0 6.6 6.2 18.0 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FAM70 PF14967.6 CDJ54061.1 - 5.5 6.4 14.6 6.1 6.2 14.6 1.0 1 0 0 1 1 1 0 FAM70 protein DUF4228 PF14009.6 CDJ54061.1 - 5.6 7.3 11.2 7.3 6.9 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) MDM10 PF12519.8 CDJ54061.1 - 5.7 5.7 12.0 5.9 5.6 12.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FAM199X PF15814.5 CDJ54061.1 - 6 5.8 12.6 7.1 5.6 12.6 1.1 1 0 0 1 1 1 0 Protein family FAM199X Velvet PF11754.8 CDJ54061.1 - 6.1 6.7 18.3 6.9 6.5 18.3 1.1 1 0 0 1 1 1 0 Velvet factor FliP PF00813.20 CDJ54061.1 - 6.1 6.7 8.2 6.9 6.5 8.2 1.1 1 0 0 1 1 1 0 FliP family CBP_BcsG PF11658.8 CDJ54061.1 - 6.1 5.1 14.2 7.5 4.8 14.2 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF2203 PF09969.9 CDJ54061.1 - 6.2 7.6 12.6 8.4 7.1 12.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) LIM_bind PF01803.16 CDJ54061.1 - 6.3 6.3 14.7 7.4 6.0 14.7 1.2 1 0 0 1 1 1 0 LIM-domain binding protein PPL5 PF18168.1 CDJ54061.1 - 6.8 5.9 11.2 7.9 5.7 11.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 LMBR1 PF04791.16 CDJ54061.1 - 7.3 5.4 7.5 7.5 5.3 7.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DDRGK PF09756.9 CDJ54061.1 - 9.1 5.8 21.3 12 5.5 21.3 1.1 1 0 0 1 1 1 0 DDRGK domain BAF1_ABF1 PF04684.13 CDJ54061.1 - 9.3 5.2 22.1 11 5.0 22.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor THOC2_N PF16134.5 CDJ54061.1 - 9.5 4.7 14.4 12 4.4 14.4 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Sin_N PF04801.13 CDJ54061.1 - 9.6 5.3 26.5 11 5.1 26.5 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region CBP4 PF07960.11 CDJ54063.1 - 0.02 14.8 18.4 0.02 14.8 18.4 2.0 1 1 1 2 2 2 0 CBP4 DUF4746 PF15928.5 CDJ54063.1 - 5.7 6.3 22.1 6.4 6.1 22.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Tim54 PF11711.8 CDJ54063.1 - 7.3 5.3 24.7 8.1 5.1 24.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Med19 PF10278.9 CDJ54063.1 - 9.5 6.1 23.6 10 6.0 23.6 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 tRNA-synt_1g PF09334.11 CDJ54064.1 - 3.6e-41 141.2 0.1 5.4e-41 140.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CDJ54064.1 - 9.9e-08 30.7 0.1 9.3e-07 27.5 0.1 1.9 1 1 1 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CDJ54064.1 - 1.4e-06 27.9 0.0 2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF508 PF04370.12 CDJ54064.1 - 2.1 8.1 6.7 6 6.6 6.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Dehydrin PF00257.19 CDJ54064.1 - 5 7.6 0.0 5 7.6 0.0 5.9 4 2 0 4 4 4 0 Dehydrin DUF45 PF01863.17 CDJ54065.1 - 0.00014 22.0 5.4 0.00021 21.4 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function DUF45 WLM PF08325.10 CDJ54065.1 - 0.016 15.3 0.3 0.016 15.3 0.3 2.9 3 1 0 3 3 3 0 WLM domain PIEZO PF15917.5 CDJ54066.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Piezo DUF3046 PF11248.8 CDJ54069.1 - 0.14 12.5 0.1 9.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) SUIM_assoc PF16619.5 CDJ54070.1 - 0.011 15.8 1.5 0.011 15.8 1.5 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 NIPSNAP PF07978.13 CDJ54070.1 - 0.021 15.0 0.4 0.16 12.2 0.1 2.5 2 0 0 2 2 2 0 NIPSNAP Peptidase_S64 PF08192.11 CDJ54070.1 - 0.073 11.6 1.3 0.11 11.0 1.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 LysR_substrate PF03466.20 CDJ54071.1 - 0.0049 16.3 1.2 0.0052 16.2 0.6 1.2 1 1 0 1 1 1 1 LysR substrate binding domain DUF2722 PF10846.8 CDJ54071.1 - 0.0069 15.4 9.8 0.0071 15.3 9.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ54071.1 - 0.029 14.0 16.3 0.03 13.9 16.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF4094 PF13334.6 CDJ54071.1 - 0.099 13.1 2.0 0.14 12.6 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) TFIIA PF03153.13 CDJ54071.1 - 0.13 12.2 18.2 0.17 11.9 18.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HD-ZIP_N PF04618.12 CDJ54071.1 - 0.14 12.6 2.3 0.16 12.5 1.8 1.3 1 1 0 1 1 1 0 HD-ZIP protein N terminus Macoilin PF09726.9 CDJ54071.1 - 0.2 10.2 7.0 0.22 10.0 7.0 1.0 1 0 0 1 1 1 0 Macoilin family AIF_C PF14721.6 CDJ54071.1 - 0.34 11.3 6.7 0.37 11.2 6.3 1.3 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF5523 PF17661.1 CDJ54071.1 - 0.41 10.3 6.9 0.51 10.0 6.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RabGAP-TBC PF00566.18 CDJ54071.1 - 0.48 10.0 7.6 0.57 9.8 7.6 1.0 1 0 0 1 1 1 0 Rab-GTPase-TBC domain SelP_N PF04592.14 CDJ54071.1 - 1 8.7 15.8 1.3 8.3 15.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ALMT PF11744.8 CDJ54071.1 - 1.6 7.5 3.9 1.5 7.5 3.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4834 PF16118.5 CDJ54071.1 - 1.7 9.7 8.5 2.1 9.4 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ54071.1 - 2 7.1 8.3 2 7.1 8.3 1.1 1 0 0 1 1 1 0 Presenilin CDK2AP PF09806.9 CDJ54071.1 - 2.8 7.9 11.4 3.7 7.5 11.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Ndc1_Nup PF09531.10 CDJ54071.1 - 7.2 5.2 7.8 8.3 5.0 7.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CRAL_TRIO PF00650.20 CDJ54072.1 - 3.6e-25 88.6 0.0 5e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ54072.1 - 0.012 15.7 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CDJ54073.1 - 1.7e-23 83.1 0.0 2.4e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Pkinase PF00069.25 CDJ54074.1 - 6.3e-13 48.7 0.0 1.2e-12 47.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 CDJ54074.1 - 6.3e-09 35.6 0.0 5.4e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ54074.1 - 0.003 16.9 0.0 0.0053 16.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase JAB PF01398.21 CDJ54076.1 - 8.7e-07 28.9 1.1 1.4e-06 28.3 0.0 1.9 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 CDJ54076.1 - 0.044 13.8 0.0 0.091 12.8 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Sporozoite_P67 PF05642.11 CDJ54076.1 - 0.58 8.2 5.9 0.81 7.7 5.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Epimerase PF01370.21 CDJ54077.1 - 2.9e-28 98.9 0.1 3.7e-17 62.6 0.1 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ54077.1 - 1.7e-25 90.2 0.0 3.1e-17 63.0 0.1 3.0 1 1 2 3 3 3 3 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDJ54077.1 - 9.5e-06 24.8 0.0 3.2e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CDJ54077.1 - 1e-05 24.9 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 CDJ54077.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.1 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CDJ54077.1 - 0.0016 17.6 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 CDJ54077.1 - 0.0041 16.6 0.0 0.0058 16.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 CDJ54077.1 - 0.03 14.2 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 CDJ54077.1 - 0.12 12.0 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.15 CDJ54077.1 - 0.18 11.9 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RRM_1 PF00076.22 CDJ54078.1 - 3.4e-08 33.2 0.0 6.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fer4_18 PF13746.6 CDJ54079.1 - 0.025 14.8 1.0 0.047 13.9 1.0 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF4834 PF16118.5 CDJ54079.1 - 0.17 12.8 0.4 0.17 12.8 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Calc_CGRP_IAPP PF00214.19 CDJ54079.1 - 1.6 9.1 9.3 0.14 12.5 3.6 2.1 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family Secretin_N_2 PF07655.13 CDJ54079.1 - 6.6 7.3 13.3 8.7 7.0 10.0 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Calpain_III PF01067.22 CDJ54080.1 - 3.9e-12 46.6 0.2 0.00045 20.5 0.0 4.4 4 1 0 4 4 4 2 Calpain large subunit, domain III TFIIA PF03153.13 CDJ54080.1 - 3.2 7.6 9.6 5.8 6.8 9.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1168 PF06658.12 CDJ54081.1 - 0.023 14.5 17.4 0.028 14.2 17.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Draxin PF15550.6 CDJ54081.1 - 0.095 12.6 11.0 0.11 12.4 11.0 1.0 1 0 0 1 1 1 0 Draxin FXR_C1 PF16096.5 CDJ54081.1 - 0.14 12.4 10.0 0.15 12.3 8.8 1.6 1 1 1 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 NST1 PF13945.6 CDJ54081.1 - 0.26 11.3 21.9 0.31 11.1 21.9 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator CPSF100_C PF13299.6 CDJ54081.1 - 0.56 10.4 12.4 0.76 9.9 12.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Band_3_cyto PF07565.13 CDJ54081.1 - 0.93 9.2 12.2 1.2 8.9 12.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDRGK PF09756.9 CDJ54081.1 - 1.2 8.7 17.7 1.5 8.4 17.7 1.1 1 0 0 1 1 1 0 DDRGK domain FAM60A PF15396.6 CDJ54081.1 - 1.5 8.8 10.9 1.8 8.5 10.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.13 CDJ54081.1 - 1.7 8.5 37.6 2.2 8.2 37.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_DNAp_acc PF04929.12 CDJ54081.1 - 1.8 7.5 13.5 2 7.3 13.5 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RR_TM4-6 PF06459.12 CDJ54081.1 - 2 8.1 16.4 2.4 7.9 16.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 XRN_M PF17846.1 CDJ54081.1 - 2.1 7.2 12.2 2.1 7.2 12.2 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Membralin PF09746.9 CDJ54081.1 - 3.1 6.8 8.9 3.3 6.7 8.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein BAT2_N PF07001.11 CDJ54081.1 - 3.5 8.1 22.7 4.7 7.6 22.7 1.2 1 0 0 1 1 1 0 BAT2 N-terminus MPM1 PF17234.2 CDJ54081.1 - 3.6 7.8 13.4 5.8 7.1 13.4 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 UPF0565 PF10561.9 CDJ54081.1 - 4 6.6 7.1 4.9 6.3 7.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Baculo_PP31 PF05311.11 CDJ54081.1 - 4.1 6.8 15.1 4.9 6.6 15.1 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Paramyxo_ncap PF00973.19 CDJ54081.1 - 4.2 6.2 14.6 4.4 6.1 14.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein eIF-3_zeta PF05091.12 CDJ54081.1 - 4.4 6.2 19.6 5.6 5.8 19.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Afi1 PF07792.12 CDJ54081.1 - 5.1 7.6 11.5 6.6 7.2 11.5 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NPR3 PF03666.13 CDJ54081.1 - 5.4 5.7 15.7 6.4 5.4 15.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sin_N PF04801.13 CDJ54081.1 - 6.6 5.8 29.2 7.8 5.6 29.2 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region DUF2721 PF11026.8 CDJ54081.1 - 7 6.6 7.0 10 6.0 7.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) Hid1 PF12722.7 CDJ54081.1 - 7.4 4.6 18.2 8.6 4.4 18.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Gti1_Pac2 PF09729.9 CDJ54081.1 - 8.3 6.5 14.2 10 6.1 14.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family CDC45 PF02724.14 CDJ54081.1 - 8.5 4.5 17.0 10 4.3 17.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 CDJ54081.1 - 9.6 4.2 16.2 11 4.0 16.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) ACDC PF14733.6 CDJ54086.1 - 4.7e-17 62.1 0.1 1.1e-16 60.9 0.1 1.6 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ54086.1 - 1.4e-09 38.0 0.3 1.4e-09 38.0 0.3 2.6 3 0 0 3 3 3 1 AP2 domain Peptidase_C2 PF00648.21 CDJ54087.1 - 0.075 12.0 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Calpain family cysteine protease DUF1118 PF06549.12 CDJ54087.1 - 0.13 12.6 0.9 0.34 11.2 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1118) Hydrolase_3 PF08282.12 CDJ54088.1 - 8.4e-39 133.8 0.0 3.7e-24 85.9 0.0 2.0 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ54088.1 - 1.1e-06 29.1 0.4 0.045 14.0 0.6 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ54088.1 - 6.4e-06 25.9 0.0 0.00071 19.2 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Phage-scaffold PF09306.10 CDJ54090.1 - 0.046 13.1 0.8 0.077 12.3 0.8 1.2 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein SH3_6 PF12913.7 CDJ54091.1 - 0.053 13.1 0.3 0.26 10.9 0.1 2.2 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) Presenilin PF01080.17 CDJ54093.1 - 1.5 7.5 42.6 1.7 7.3 42.6 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ54093.1 - 7.2 6.4 36.7 9.4 6.0 36.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RF-1 PF00472.20 CDJ54094.1 - 1.8e-12 47.2 7.4 3.8e-12 46.2 7.4 1.5 1 0 0 1 1 1 1 RF-1 domain Lipoprotein_10 PF03202.13 CDJ54095.1 - 0.069 13.6 0.2 0.59 10.6 0.0 2.2 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region RT_RNaseH PF17917.1 CDJ54096.1 - 6e-29 100.4 0.0 1.2e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ54096.1 - 1.5e-27 95.6 0.0 3.2e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ54096.1 - 4.3e-15 55.9 0.0 1.3e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CDJ54096.1 - 1.5e-13 50.7 0.0 2.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ54096.1 - 3e-10 40.0 0.0 7.7e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 CDJ54096.1 - 3.4e-06 27.6 0.0 7.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ54096.1 - 3.3e-05 24.4 0.0 6.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CDJ54096.1 - 0.0072 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease TnpV PF14198.6 CDJ54098.1 - 0.097 12.7 0.1 0.17 11.8 0.1 1.5 1 1 0 1 1 1 0 Transposon-encoded protein TnpV DUF4179 PF13786.6 CDJ54098.1 - 0.12 12.8 0.3 0.22 12.0 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) RRM_1 PF00076.22 CDJ54099.1 - 7.9e-12 44.8 0.0 1.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.19 CDJ54100.1 - 0.00043 20.3 15.3 0.00043 20.3 15.3 3.0 2 1 0 2 2 2 1 SPX domain SLC12 PF03522.15 CDJ54100.1 - 5.3 6.0 29.3 1.8 7.5 3.8 2.3 2 0 0 2 2 2 0 Solute carrier family 12 SARAF PF06682.12 CDJ54101.1 - 6.5e-05 22.7 48.1 9.9e-05 22.1 0.1 5.8 4 2 1 5 5 5 2 SOCE-associated regulatory factor of calcium homoeostasis SR-25 PF10500.9 CDJ54101.1 - 0.00014 21.6 5.4 0.00014 21.6 5.4 7.3 6 2 1 7 7 7 2 Nuclear RNA-splicing-associated protein TMEM51 PF15345.6 CDJ54101.1 - 0.0022 17.9 9.1 0.0022 17.9 9.1 6.9 7 2 0 7 7 7 1 Transmembrane protein 51 DUF2722 PF10846.8 CDJ54101.1 - 0.0027 16.7 5.4 0.0027 16.7 5.4 9.2 7 3 2 9 9 9 3 Protein of unknown function (DUF2722) PIG-U PF06728.13 CDJ54101.1 - 1.6 7.7 3.1 5.2 6.0 0.5 2.8 3 0 0 3 3 3 0 GPI transamidase subunit PIG-U Cytochrom_B558a PF05038.13 CDJ54101.1 - 2.5 7.6 7.1 0.19 11.3 0.1 2.7 3 0 0 3 3 3 0 Cytochrome Cytochrome b558 alpha-subunit Dpy19 PF10034.9 CDJ54101.1 - 7 4.7 8.2 17 3.4 0.2 3.3 3 0 0 3 3 3 0 Q-cell neuroblast polarisation OATP PF03137.20 CDJ54101.1 - 7.3 4.8 14.1 2.1 6.5 0.4 3.9 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family CD20 PF04103.15 CDJ54103.1 - 0.25 11.4 0.1 0.52 10.4 0.1 1.5 1 0 0 1 1 1 0 CD20-like family Glt_symporter PF03616.14 CDJ54103.1 - 0.4 9.3 1.5 0.76 8.4 1.5 1.4 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF2232 PF09991.9 CDJ54103.1 - 0.72 9.0 3.8 1 8.5 3.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Helicase_RecD PF05127.14 CDJ54103.1 - 0.9 9.4 12.2 17 5.2 0.1 2.5 2 0 0 2 2 2 0 Helicase NOA36 PF06524.12 CDJ54103.1 - 2.7 7.3 26.9 0.66 9.2 16.4 2.5 2 0 0 2 2 2 0 NOA36 protein RskA PF10099.9 CDJ54103.1 - 4.5 7.5 68.6 0.18 12.1 30.8 4.1 1 1 3 4 4 4 0 Anti-sigma-K factor rskA DcuA_DcuB PF03605.14 CDJ54103.1 - 5.7 5.7 7.2 0.34 9.7 1.4 1.9 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter KR PF08659.10 CDJ54105.1 - 2.9e-52 177.2 0.0 9.5e-52 175.5 0.0 1.9 1 1 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 CDJ54105.1 - 4.2e-39 134.9 1.7 8.2e-39 134.0 1.7 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 CDJ54105.1 - 2.8e-16 59.6 0.2 1.2e-10 41.2 0.1 2.4 2 0 0 2 2 2 2 Polyketide synthase dehydratase PP-binding PF00550.25 CDJ54105.1 - 1.3e-13 51.1 0.1 2.7e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 CDJ54105.1 - 4.5e-10 39.3 0.0 1.4e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase ketoacyl-synt PF00109.26 CDJ54106.1 - 2e-66 224.2 0.0 2.6e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CDJ54106.1 - 2.7e-36 124.2 0.1 4.3e-36 123.5 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain AP2 PF00847.20 CDJ54108.1 - 5.9e-05 23.2 2.2 5.9e-05 23.2 2.2 3.4 2 0 0 2 2 2 1 AP2 domain PI3K_P85_iSH2 PF16454.5 CDJ54112.1 - 0.0017 18.0 0.5 0.0018 17.9 0.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ADIP PF11559.8 CDJ54112.1 - 0.0031 17.6 1.2 0.0033 17.5 1.2 1.0 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Suppressor_APC PF11414.8 CDJ54112.1 - 0.0033 17.5 0.7 0.0042 17.1 0.7 1.1 1 0 0 1 1 1 1 Adenomatous polyposis coli tumour suppressor protein APG6_N PF17675.1 CDJ54112.1 - 0.0072 16.9 1.5 0.0096 16.4 1.5 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region PqqD PF05402.12 CDJ54112.1 - 0.011 16.0 0.4 0.019 15.3 0.2 1.5 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Arc_C PF18162.1 CDJ54112.1 - 0.016 15.0 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 Arc C-lobe CorA PF01544.18 CDJ54112.1 - 0.018 14.4 0.4 0.02 14.2 0.4 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ZapB PF06005.12 CDJ54112.1 - 0.075 13.5 3.5 0.098 13.1 3.5 1.2 1 0 0 1 1 1 0 Cell division protein ZapB Tubulin_3 PF14881.6 CDJ54112.1 - 0.16 11.7 0.0 0.16 11.6 0.0 1.0 1 0 0 1 1 1 0 Tubulin domain DUF2722 PF10846.8 CDJ54113.1 - 0.0015 17.5 8.4 0.0015 17.5 8.4 4.1 3 1 0 3 3 3 1 Protein of unknown function (DUF2722) DUF3357 PF11837.8 CDJ54113.1 - 2.5 8.6 11.5 0.63 10.5 1.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DNA_pol_phi PF04931.13 CDJ54114.1 - 0.12 10.5 20.8 0.15 10.1 20.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC27 PF09507.10 CDJ54114.1 - 0.16 11.3 42.1 0.18 11.1 42.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 IMUP PF15761.5 CDJ54115.1 - 0.018 15.7 12.2 0.018 15.7 12.2 2.1 1 1 1 2 2 2 0 Immortalisation up-regulated protein Androgen_recep PF02166.16 CDJ54115.1 - 0.56 9.0 16.5 0.71 8.6 16.5 1.2 1 0 0 1 1 1 0 Androgen receptor TCP PF03634.13 CDJ54115.1 - 2.2 8.8 18.4 2.6 8.6 18.4 1.2 1 0 0 1 1 1 0 TCP family transcription factor NACHT_N PF17100.5 CDJ54115.1 - 2.4 7.9 10.4 1.6 8.6 9.0 1.4 1 1 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase DUF5345 PF17280.2 CDJ54115.1 - 8.2 6.5 7.1 14 5.8 7.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) ASD2 PF08687.11 CDJ54115.1 - 8.9 5.8 14.7 11 5.5 14.7 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF2722 PF10846.8 CDJ54116.1 - 0.0016 17.4 6.4 0.0016 17.4 6.4 4.2 3 2 1 4 4 4 1 Protein of unknown function (DUF2722) DUF2464 PF10240.9 CDJ54117.1 - 0.3 10.6 6.1 0.33 10.5 6.1 1.0 1 0 0 1 1 1 0 Multivesicular body subunit 12 Bac_luciferase PF00296.20 CDJ54117.1 - 0.45 9.9 4.8 0.59 9.5 4.8 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase Folliculin PF11704.8 CDJ54117.1 - 0.46 10.3 11.9 0.57 10.0 11.9 1.0 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport SpoIIP PF07454.11 CDJ54117.1 - 0.92 8.9 14.4 0.98 8.8 14.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CobT PF06213.12 CDJ54117.1 - 1 8.7 26.7 1.1 8.6 26.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Gti1_Pac2 PF09729.9 CDJ54117.1 - 1.1 9.4 11.8 1.3 9.1 11.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Zip PF02535.22 CDJ54117.1 - 2.2 7.4 7.0 2.2 7.4 7.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SspB PF04386.13 CDJ54117.1 - 2.9 7.8 13.8 3.2 7.6 13.8 1.1 1 0 0 1 1 1 0 Stringent starvation protein B DDHD PF02862.17 CDJ54117.1 - 3.7 7.7 14.2 4.3 7.4 14.2 1.1 1 0 0 1 1 1 0 DDHD domain Pex14_N PF04695.13 CDJ54117.1 - 3.9 8.1 21.0 4.8 7.8 21.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ctr PF04145.15 CDJ54117.1 - 5.7 7.5 8.1 6.8 7.3 8.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF4569 PF15133.6 CDJ54117.1 - 7 6.3 17.6 8.2 6.1 17.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF913 PF06025.12 CDJ54117.1 - 7.1 5.5 11.9 8.5 5.2 11.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CDJ54117.1 - 7.6 6.3 16.6 8.9 6.0 16.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ54117.1 - 8 6.4 12.7 8.9 6.3 12.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ54117.1 - 9.4 4.9 20.1 9.9 4.8 20.1 1.0 1 0 0 1 1 1 0 Presenilin PGI PF00342.19 CDJ54119.1 - 5.6e-26 91.2 0.3 7.4e-26 90.8 0.3 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase FAM176 PF14851.6 CDJ54120.1 - 0.00085 19.0 7.5 0.004 16.8 0.3 3.0 2 1 1 3 3 3 2 FAM176 family SUIM_assoc PF16619.5 CDJ54120.1 - 0.02 14.9 0.6 0.02 14.9 0.6 4.4 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 TMEM154 PF15102.6 CDJ54120.1 - 0.022 14.6 0.6 0.022 14.6 0.6 2.3 2 1 0 2 2 2 0 TMEM154 protein family DUF1418 PF07214.12 CDJ54120.1 - 0.81 9.6 6.2 1.8 8.5 1.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1418) Afaf PF15339.6 CDJ54120.1 - 1.1 9.0 6.1 2.7 7.7 0.5 2.6 2 1 1 3 3 3 0 Acrosome formation-associated factor EphA2_TM PF14575.6 CDJ54120.1 - 6.6 7.7 11.5 17 6.3 0.1 3.4 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain RNase_H2_suC PF08615.11 CDJ54120.1 - 8.9 6.5 10.4 9.7 6.4 3.7 2.5 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FxsA PF04186.13 CDJ54120.1 - 9 6.5 18.8 3 8.0 1.3 3.5 2 1 2 4 4 4 0 FxsA cytoplasmic membrane protein EOS1 PF12326.8 CDJ54120.1 - 9.6 6.1 8.2 7.8 6.4 0.9 2.5 2 1 0 2 2 2 0 N-glycosylation protein UPF0542 PF15086.6 CDJ54120.1 - 9.7 6.2 15.4 0.95 9.4 1.3 3.4 3 1 0 3 3 3 0 Uncharacterised protein family UPF0542 Collagen PF01391.18 CDJ54121.1 - 0.0048 16.6 3.2 0.0076 16.0 3.2 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF4149 PF13664.6 CDJ54122.1 - 0.13 12.6 0.2 0.13 12.6 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) RskA PF10099.9 CDJ54123.1 - 1.4e-05 25.5 0.9 1.4e-05 25.5 0.9 4.3 3 1 1 4 4 4 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ54123.1 - 0.0025 17.5 12.5 0.0034 17.0 12.5 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 CDJ54123.1 - 0.0041 16.1 9.0 0.0041 16.1 9.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ54123.1 - 0.0052 16.8 21.8 0.0066 16.5 21.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CDJ54123.1 - 0.026 13.5 19.2 0.038 13.0 19.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Neur_chan_memb PF02932.16 CDJ54123.1 - 0.42 10.6 4.0 0.66 10.0 4.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hist_deacetyl PF00850.19 CDJ54123.1 - 0.73 9.2 4.2 2 7.8 4.2 1.7 1 1 0 1 1 1 0 Histone deacetylase domain SHR3_chaperone PF08229.11 CDJ54123.1 - 1.2 8.0 7.3 1.6 7.7 0.0 2.4 2 0 0 2 2 2 0 ER membrane protein SH3 Presenilin PF01080.17 CDJ54123.1 - 3.8 6.2 6.5 5.7 5.6 6.5 1.4 1 0 0 1 1 1 0 Presenilin NAPRTase PF04095.16 CDJ54124.1 - 0.01 15.5 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_C PF17956.1 CDJ54124.1 - 0.089 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain FAD-SLDH PF12318.8 CDJ54125.1 - 3.4 7.7 13.5 0.41 10.7 8.4 2.1 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase SR-25 PF10500.9 CDJ54125.1 - 4.9 6.7 30.9 0.02 14.5 16.2 2.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.19 CDJ54126.1 - 1.1e-13 51.5 21.0 2.6e-13 50.4 21.0 1.5 1 1 0 1 1 1 1 60s Acidic ribosomal protein Kelch_1 PF01344.25 CDJ54128.1 - 1.5e-42 142.9 0.0 1.8e-11 43.5 0.1 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 CDJ54128.1 - 1.5e-26 91.8 0.0 5.2e-05 23.4 0.0 4.3 2 1 2 4 4 4 4 Kelch motif Kelch_4 PF13418.6 CDJ54128.1 - 4.4e-16 58.6 0.0 0.016 15.2 0.0 4.3 3 1 1 4 4 4 4 Galactose oxidase, central domain BTB_2 PF02214.22 CDJ54128.1 - 2e-15 56.9 0.3 6.3e-15 55.3 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 CDJ54128.1 - 1.6e-12 46.8 0.0 0.0054 16.7 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 CDJ54128.1 - 7.5e-12 45.2 0.0 0.0017 18.6 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ54128.1 - 3.4e-08 33.3 0.2 0.0076 16.2 0.1 3.5 3 0 0 3 3 3 2 Kelch motif DUF1918 PF08940.11 CDJ54128.1 - 0.096 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) LprI PF07007.12 CDJ54128.1 - 0.21 12.3 5.5 0.58 10.9 5.5 1.9 1 0 0 1 1 1 0 Lysozyme inhibitor LprI EF-hand_14 PF17959.1 CDJ54128.1 - 0.39 11.1 2.7 0.72 10.2 2.7 1.3 1 0 0 1 1 1 0 EF-hand domain Band_3_cyto PF07565.13 CDJ54128.1 - 1 9.1 4.8 1.4 8.6 4.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TraT PF05818.12 CDJ54129.1 - 0.0023 17.6 9.4 0.0029 17.3 9.4 1.1 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein SR-25 PF10500.9 CDJ54129.1 - 0.0054 16.4 9.9 0.006 16.2 9.9 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Shadoo PF14999.6 CDJ54129.1 - 0.015 15.4 5.3 0.017 15.2 5.3 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective NEMP PF10225.9 CDJ54129.1 - 0.063 12.9 3.8 0.073 12.7 3.8 1.0 1 0 0 1 1 1 0 NEMP family Peptidase_S49_N PF08496.10 CDJ54129.1 - 0.086 12.9 6.2 0.097 12.7 6.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FHIPEP PF00771.20 CDJ54129.1 - 0.09 11.2 6.7 0.1 11.0 6.7 1.0 1 0 0 1 1 1 0 FHIPEP family Connexin PF00029.19 CDJ54129.1 - 0.16 11.7 4.6 0.14 11.9 4.6 1.1 1 0 0 1 1 1 0 Connexin DUF2722 PF10846.8 CDJ54129.1 - 0.16 10.8 26.6 0.2 10.6 26.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Ureide_permease PF07168.11 CDJ54129.1 - 0.18 10.5 4.3 0.23 10.2 4.3 1.2 1 0 0 1 1 1 0 Ureide permease PA26 PF04636.13 CDJ54129.1 - 0.18 10.7 10.1 0.19 10.6 10.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) G0-G1_switch_2 PF15103.6 CDJ54129.1 - 0.29 11.6 5.9 0.33 11.4 5.9 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 MelC1 PF06236.11 CDJ54129.1 - 0.34 11.0 9.8 0.41 10.7 9.8 1.1 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 CLN3 PF02487.17 CDJ54129.1 - 0.35 9.9 5.4 0.33 9.9 5.4 1.1 1 0 0 1 1 1 0 CLN3 protein eIF-3_zeta PF05091.12 CDJ54129.1 - 0.54 9.2 16.4 0.59 9.0 16.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4820 PF16091.5 CDJ54129.1 - 0.57 9.5 10.3 0.66 9.3 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Ctr PF04145.15 CDJ54129.1 - 0.62 10.7 5.3 0.7 10.5 5.3 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Presenilin PF01080.17 CDJ54129.1 - 0.65 8.7 15.8 0.71 8.6 15.8 1.0 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 CDJ54129.1 - 0.75 10.1 22.5 1.3 9.3 22.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CSG2 PF16965.5 CDJ54129.1 - 0.83 8.5 4.2 0.86 8.5 4.2 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator SpoIIP PF07454.11 CDJ54129.1 - 0.97 8.8 11.5 1 8.8 11.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Baculo_PP31 PF05311.11 CDJ54129.1 - 0.99 8.8 11.4 1.1 8.7 11.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Serinc PF03348.15 CDJ54129.1 - 1.1 8.1 8.2 1.2 8.0 8.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.13 CDJ54129.1 - 1.4 8.9 37.3 1.6 8.6 37.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit R_equi_Vir PF05526.11 CDJ54129.1 - 1.4 8.7 10.4 1.8 8.4 10.4 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Spt20 PF12090.8 CDJ54129.1 - 1.5 8.4 36.8 1.7 8.2 36.8 1.1 1 0 0 1 1 1 0 Spt20 family Velvet PF11754.8 CDJ54129.1 - 1.9 8.4 14.0 1.9 8.4 14.0 1.0 1 0 0 1 1 1 0 Velvet factor DUF1980 PF09323.10 CDJ54129.1 - 1.9 8.4 8.2 2 8.3 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) AIF_C PF14721.6 CDJ54129.1 - 2.2 8.6 10.8 2.7 8.3 10.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EIIBC-GUT_N PF03612.14 CDJ54129.1 - 2.3 7.9 11.1 2.6 7.8 11.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DDHD PF02862.17 CDJ54129.1 - 2.5 8.2 13.6 3 8.0 13.6 1.1 1 0 0 1 1 1 0 DDHD domain FAM199X PF15814.5 CDJ54129.1 - 2.9 6.8 16.6 3.4 6.7 16.6 1.0 1 0 0 1 1 1 0 Protein family FAM199X Suf PF05843.14 CDJ54129.1 - 3.1 7.7 19.0 3.3 7.6 19.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ54129.1 - 3.6 7.6 11.1 3.6 7.6 11.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spem1 PF15670.5 CDJ54129.1 - 3.8 7.0 15.4 4.3 6.8 15.4 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 Spore_coat_CotO PF14153.6 CDJ54129.1 - 3.9 7.4 19.1 4.1 7.3 19.1 1.0 1 0 0 1 1 1 0 Spore coat protein CotO FAM176 PF14851.6 CDJ54129.1 - 4 7.1 8.2 4.9 6.8 8.2 1.2 1 0 0 1 1 1 0 FAM176 family TrbI PF03743.14 CDJ54129.1 - 4.4 7.1 14.5 5.3 6.8 14.5 1.1 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein RR_TM4-6 PF06459.12 CDJ54129.1 - 4.9 6.9 12.9 5.3 6.8 12.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2232 PF09991.9 CDJ54129.1 - 5 6.2 5.2 5.7 6.0 5.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Band_3_cyto PF07565.13 CDJ54129.1 - 6 6.6 11.6 6.6 6.5 11.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CPSF100_C PF13299.6 CDJ54129.1 - 6.3 6.9 11.1 8.1 6.6 11.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal OATP PF03137.20 CDJ54129.1 - 7.2 4.8 7.3 7.3 4.7 7.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TERB2 PF15101.6 CDJ54129.1 - 7.8 6.5 17.8 9.1 6.3 17.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EOS1 PF12326.8 CDJ54129.1 - 8.6 6.3 8.4 9.4 6.1 8.4 1.1 1 0 0 1 1 1 0 N-glycosylation protein Herpes_UL32 PF06070.11 CDJ54129.1 - 8.7 3.9 18.6 9.5 3.8 18.6 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF5521 PF17659.1 CDJ54129.1 - 8.7 4.0 10.9 8.3 4.1 10.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) MAJIN PF15077.6 CDJ54129.1 - 8.9 6.0 10.1 9.7 5.9 10.1 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein V_ATPase_I PF01496.19 CDJ54129.1 - 9.4 4.0 13.0 9.8 3.9 13.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lactamase_B_2 PF12706.7 CDJ54132.1 - 4.4e-23 81.9 10.5 8.6e-17 61.3 0.0 3.5 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDJ54132.1 - 9.4e-06 25.6 0.0 9.4e-06 25.6 0.0 2.6 3 0 0 3 3 3 1 Beta-lactamase superfamily domain PI3_PI4_kinase PF00454.27 CDJ54133.1 - 7e-30 104.7 1.5 4.1e-27 95.6 0.2 3.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CDJ54133.1 - 1.8e-06 27.5 0.1 0.0021 17.5 0.0 2.5 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 CDJ54133.1 - 0.0082 16.1 1.2 0.057 13.3 0.0 3.1 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 CSN8_PSD8_EIF3K PF10075.9 CDJ54133.1 - 0.078 13.0 0.3 0.29 11.1 0.1 2.0 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family Thioredoxin_4 PF13462.6 CDJ54133.1 - 1.8 8.7 10.0 0.55 10.4 0.0 4.0 2 1 0 3 3 3 0 Thioredoxin SPT6_acidic PF14632.6 CDJ54134.1 - 0.29 11.7 8.6 0.32 11.6 8.6 1.1 1 0 0 1 1 1 0 Acidic N-terminal SPT6 BRD4_CDT PF17105.5 CDJ54134.1 - 7.1 6.3 6.4 11 5.8 0.5 2.2 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 Paf1 PF03985.13 CDJ54134.1 - 9.9 5.0 7.4 10 5.0 7.4 1.0 1 0 0 1 1 1 0 Paf1 BUD22 PF09073.10 CDJ54135.1 - 0.072 12.4 25.9 0.091 12.1 25.9 1.2 1 0 0 1 1 1 0 BUD22 DUF3246 PF11596.8 CDJ54135.1 - 0.53 9.7 10.2 0.76 9.2 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) BSP_II PF05432.11 CDJ54135.1 - 1.1 8.9 22.0 1.3 8.7 22.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Presenilin PF01080.17 CDJ54135.1 - 3.7 6.2 12.6 4.5 5.9 12.6 1.2 1 0 0 1 1 1 0 Presenilin ADP_ribosyl_GH PF03747.14 CDJ54135.1 - 4.1 7.1 13.1 5.8 6.6 13.1 1.4 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase PIEZO PF15917.5 CDJ54135.1 - 4.9 6.6 9.4 6.6 6.1 9.4 1.3 1 0 0 1 1 1 0 Piezo Zip PF02535.22 CDJ54135.1 - 6.8 5.8 6.2 9.2 5.4 6.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SURF2 PF05477.11 CDJ54135.1 - 7.7 6.1 14.5 9.3 5.9 14.5 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Plasmodium_Vir PF05795.11 CDJ54135.1 - 8.3 5.7 10.3 10 5.4 10.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM60A PF15396.6 CDJ54136.1 - 0.64 10.0 5.4 0.75 9.8 5.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SARAF PF06682.12 CDJ54136.1 - 0.69 9.5 13.6 0.81 9.3 13.6 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2259 PF10016.9 CDJ54136.1 - 0.96 9.4 9.4 1.1 9.1 9.4 1.1 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) Presenilin PF01080.17 CDJ54136.1 - 1.3 7.7 10.1 1.5 7.5 10.1 1.0 1 0 0 1 1 1 0 Presenilin Exonuc_VII_L PF02601.15 CDJ54136.1 - 7.7 6.0 15.9 9.9 5.6 15.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cation_ATPase PF13246.6 CDJ54138.1 - 0.042 13.9 0.0 0.84 9.8 0.0 2.4 2 0 0 2 2 2 0 Cation transport ATPase (P-type) EVI2A PF05399.11 CDJ54138.1 - 0.19 11.3 3.9 0.33 10.5 3.9 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Secretin_N_2 PF07655.13 CDJ54138.1 - 1.2 9.7 10.6 2 9.0 10.6 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF4131 PF13567.6 CDJ54138.1 - 2.2 7.9 7.2 0.14 11.8 0.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) TFIIA PF03153.13 CDJ54140.1 - 0.00031 20.8 41.8 0.0014 18.7 9.7 2.2 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ54140.1 - 0.0032 17.1 6.8 0.0032 17.1 6.8 3.1 4 1 0 4 4 3 1 Spt20 family Isy1 PF06246.12 CDJ54140.1 - 0.0072 15.9 4.1 0.47 10.0 0.0 2.3 2 0 0 2 2 2 2 Isy1-like splicing family SPX PF03105.19 CDJ54140.1 - 0.037 13.9 18.1 18 5.1 18.1 2.8 1 1 0 1 1 1 0 SPX domain Peptidase_S49_N PF08496.10 CDJ54140.1 - 0.072 13.2 8.1 1.6 8.7 0.6 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Med15 PF09606.10 CDJ54140.1 - 0.23 10.1 31.7 0.16 10.6 8.5 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3381 PF11861.8 CDJ54140.1 - 0.24 11.2 11.0 1.6 8.5 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF4770 PF15994.5 CDJ54140.1 - 0.44 10.8 12.1 1.7 8.9 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) EPL1 PF10513.9 CDJ54140.1 - 1.4 9.2 10.4 5.7 7.3 0.6 3.3 3 0 0 3 3 3 0 Enhancer of polycomb-like CLN3 PF02487.17 CDJ54140.1 - 3.1 6.7 5.8 2.7 7.0 0.5 2.6 3 0 0 3 3 3 0 CLN3 protein DUF3506 PF12014.8 CDJ54140.1 - 3.7 7.5 5.7 2.6 8.0 0.3 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF3506) PEX11 PF05648.14 CDJ54140.1 - 5.1 6.5 8.4 4.4 6.7 1.1 2.5 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) eIF-3_zeta PF05091.12 CDJ54140.1 - 7.1 5.5 15.3 1.4 7.8 3.9 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAPA-1 PF04795.12 CDJ54140.1 - 7.5 7.4 15.9 0.4 11.5 0.4 3.4 3 0 0 3 3 3 0 PAPA-1-like conserved region DUF3464 PF11947.8 CDJ54140.1 - 7.7 6.3 10.3 15 5.3 0.4 2.8 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 TetR_C_35 PF18556.1 CDJ54141.1 - 0.024 14.7 0.3 0.55 10.4 0.1 2.6 1 1 2 3 3 3 0 Bacterial Tetracyclin repressor, C-terminal domain DUF3599 PF12206.8 CDJ54141.1 - 0.062 13.7 0.1 0.093 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) SET PF00856.28 CDJ54142.1 - 5.6e-05 23.6 0.1 0.038 14.4 0.0 3.5 2 1 0 3 3 3 2 SET domain Surfac_D-trimer PF09006.11 CDJ54143.1 - 0.19 11.6 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation DUF1906 PF08924.11 CDJ54144.1 - 1.2 9.3 4.3 1.9 8.6 3.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1906) CEL_III_C PF18054.1 CDJ54144.1 - 8.8 6.4 14.8 32 4.5 14.8 1.9 1 1 0 1 1 1 0 CEL-III C-terminal CYYR1 PF10873.8 CDJ54145.1 - 5.1 7.5 5.4 9.5 6.7 5.4 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 WD40 PF00400.32 CDJ54146.1 - 1e-05 26.1 0.3 0.003 18.4 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Ferlin_C PF16165.5 CDJ54146.1 - 6.4 6.7 7.1 6.4 6.7 4.4 2.2 2 0 0 2 2 2 0 Ferlin C-terminus Ureide_permease PF07168.11 CDJ54146.1 - 9.7 4.8 7.6 20 3.8 5.2 2.1 2 0 0 2 2 2 0 Ureide permease HMG_box PF00505.19 CDJ54148.1 - 3.3e-13 49.8 5.6 1.2e-12 48.1 5.6 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ54148.1 - 3.3e-05 24.4 4.6 3.3e-05 24.4 4.6 2.6 3 0 0 3 3 3 1 HMG-box domain SET PF00856.28 CDJ54148.1 - 0.026 14.9 0.0 0.026 14.9 0.0 3.6 2 1 0 2 2 2 0 SET domain Tetraspanin PF00335.20 CDJ54148.1 - 0.2 11.3 0.0 0.34 10.6 0.0 1.4 1 1 0 1 1 1 0 Tetraspanin family Hydin_ADK PF17213.3 CDJ54149.1 - 0.006 16.9 3.9 0.016 15.5 3.9 1.6 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain Dehydrin PF00257.19 CDJ54151.1 - 3.2 8.3 16.3 4.7 7.7 16.3 1.2 1 0 0 1 1 1 0 Dehydrin Sporozoite_P67 PF05642.11 CDJ54151.1 - 3.8 5.5 13.5 4.6 5.2 13.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Draxin PF15550.6 CDJ54152.1 - 2.8 7.7 29.2 4.2 7.2 29.2 1.2 1 0 0 1 1 1 0 Draxin Auxin_canalis PF05703.11 CDJ54152.1 - 3.6 7.5 30.2 4.8 7.0 30.2 1.1 1 0 0 1 1 1 0 Auxin canalisation Caldesmon PF02029.15 CDJ54152.1 - 4.5 5.9 37.7 6.7 5.4 37.7 1.2 1 0 0 1 1 1 0 Caldesmon Sugar_tr PF00083.24 CDJ54154.1 - 7.5e-16 58.0 0.5 7.5e-16 58.0 0.5 2.7 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 CDJ54154.1 - 0.0042 16.0 1.5 0.0042 16.0 1.5 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Pex26 PF07163.12 CDJ54154.1 - 0.012 15.0 7.7 0.012 15.0 7.7 2.5 1 1 1 2 2 1 0 Pex26 protein Glyco_hydro_92N PF17678.1 CDJ54154.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 92 N-terminal domain Connexin PF00029.19 CDJ54154.1 - 0.14 11.9 12.4 1.9 8.2 10.4 2.1 2 0 0 2 2 2 0 Connexin V_ATPase_I PF01496.19 CDJ54154.1 - 0.17 9.7 22.3 0.78 7.6 0.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family EOS1 PF12326.8 CDJ54154.1 - 0.21 11.5 8.5 5.1 7.0 0.0 2.2 2 0 0 2 2 2 0 N-glycosylation protein OATP PF03137.20 CDJ54154.1 - 0.24 9.7 8.8 2 6.6 6.0 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Shisa PF13908.6 CDJ54154.1 - 1.3 9.3 17.9 6.6 6.9 0.2 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Peptidase_S49_N PF08496.10 CDJ54154.1 - 2.3 8.3 20.5 5 7.2 0.3 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CLN3 PF02487.17 CDJ54154.1 - 2.5 7.0 22.8 2.6 7.0 1.3 2.1 1 1 1 2 2 2 0 CLN3 protein Cadherin_C_2 PF16492.5 CDJ54154.1 - 2.6 8.9 5.1 46 4.9 3.2 2.6 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal SpoIIP PF07454.11 CDJ54154.1 - 3.6 7.0 22.1 2.4 7.5 13.7 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 CDJ54154.1 - 5.5 7.1 21.8 8 6.5 0.1 2.9 3 0 0 3 3 3 0 E2F-associated phosphoprotein DUF4131 PF13567.6 CDJ54154.1 - 5.5 6.6 17.7 2.6 7.7 7.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Nucleoside_tran PF01733.18 CDJ54154.1 - 7.5 5.8 13.5 18 4.6 8.5 2.1 1 1 1 2 2 2 0 Nucleoside transporter YABBY PF04690.13 CDJ54154.1 - 7.8 7.0 19.6 11 6.5 13.5 2.1 2 0 0 2 2 2 0 YABBY protein DUF4045 PF13254.6 CDJ54155.1 - 6 6.4 16.5 7 6.2 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SF3a60_bindingd PF12108.8 CDJ54157.1 - 1.1e-08 34.8 0.5 1.9e-08 34.0 0.5 1.4 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain YusW PF14039.6 CDJ54157.1 - 0.66 10.5 5.6 0.32 11.6 2.7 1.9 1 1 1 2 2 2 0 YusW-like protein Trypan_PARP PF05887.11 CDJ54159.1 - 4.3 7.3 40.1 8.1e+02 -0.0 40.1 2.0 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.16 CDJ54161.1 - 6e-12 45.2 24.4 7e-09 35.1 9.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily V_ATPase_I PF01496.19 CDJ54161.1 - 2.8e-06 25.6 4.1 0.00025 19.1 0.5 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family CLN3 PF02487.17 CDJ54161.1 - 4e-06 26.2 5.0 0.011 14.8 0.1 2.4 2 0 0 2 2 2 2 CLN3 protein MFS_1_like PF12832.7 CDJ54161.1 - 5.7e-05 22.1 0.0 0.045 12.6 0.0 2.9 1 1 0 1 1 1 1 MFS_1 like family FAM176 PF14851.6 CDJ54161.1 - 0.00012 21.8 2.5 0.11 12.2 0.3 2.9 3 0 0 3 3 2 2 FAM176 family DDHD PF02862.17 CDJ54161.1 - 0.027 14.6 5.0 1.8 8.7 3.0 2.2 2 0 0 2 2 2 0 DDHD domain O-antigen_lig PF13425.6 CDJ54161.1 - 0.039 12.8 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 O-antigen ligase like membrane protein EOS1 PF12326.8 CDJ54161.1 - 0.072 13.0 0.0 4.5 7.2 0.1 2.3 2 0 0 2 2 2 0 N-glycosylation protein Pet20 PF08692.10 CDJ54161.1 - 0.13 13.0 2.2 19 6.0 0.8 2.4 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Connexin PF00029.19 CDJ54161.1 - 0.3 10.8 6.3 3.7 7.2 4.0 2.6 2 0 0 2 2 2 0 Connexin RNA_pol_Rpc4 PF05132.14 CDJ54161.1 - 0.35 11.3 18.2 1.7 9.1 2.8 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 TRAP_alpha PF03896.16 CDJ54161.1 - 0.62 9.2 6.0 1.4 8.0 3.5 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SID-1_RNA_chan PF13965.6 CDJ54161.1 - 0.62 8.4 5.3 3.3 6.0 2.6 2.3 2 1 0 2 2 2 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 CDJ54161.1 - 0.63 11.0 16.4 4.3 8.3 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) TMEM51 PF15345.6 CDJ54161.1 - 1.5 8.6 14.9 2.7 7.7 7.8 2.9 3 0 0 3 3 3 0 Transmembrane protein 51 BORG_CEP PF14957.6 CDJ54161.1 - 2.5 9.3 9.7 18 6.5 3.9 2.8 3 0 0 3 3 3 0 Cdc42 effector FAM60A PF15396.6 CDJ54161.1 - 2.6 8.0 11.0 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein Family FAM60A RR_TM4-6 PF06459.12 CDJ54161.1 - 3 7.6 16.9 4.7 7.0 2.0 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CCDC53 PF10152.9 CDJ54161.1 - 3.9 7.9 20.3 7.6 6.9 7.5 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex EMC3_TMCO1 PF01956.16 CDJ54161.1 - 4.9 6.9 11.9 2.7 7.7 5.2 2.6 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like PIP5K PF01504.18 CDJ54161.1 - 6.6 5.9 10.2 66 2.6 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase OSTbeta PF15048.6 CDJ54161.1 - 9.5 6.4 13.6 1.4 9.0 5.0 2.5 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein RskA PF10099.9 CDJ54162.1 - 0.0058 16.9 13.1 0.0058 16.9 13.1 4.3 2 1 1 3 3 3 1 Anti-sigma-K factor rskA Kinase-like PF14531.6 CDJ54165.1 - 2.1e-07 30.5 0.0 1.1e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ54165.1 - 8.5e-05 22.0 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ54165.1 - 0.0001 21.8 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Herpes_UL6 PF01763.16 CDJ54166.1 - 0.0076 14.8 1.6 0.0092 14.5 1.6 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like DUF445 PF04286.12 CDJ54166.1 - 0.038 13.8 5.7 0.06 13.1 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF5314 PF17241.2 CDJ54166.1 - 0.059 13.0 0.8 0.092 12.4 0.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5314) EcsC PF12787.7 CDJ54166.1 - 0.068 12.8 0.9 0.092 12.4 0.9 1.1 1 0 0 1 1 1 0 EcsC protein family SecA_SW PF07516.13 CDJ54166.1 - 0.22 11.6 3.7 0.32 11.0 3.7 1.2 1 0 0 1 1 1 0 SecA Wing and Scaffold domain CEL_III_C PF18054.1 CDJ54166.1 - 0.23 11.5 5.6 0.37 10.9 5.6 1.3 1 0 0 1 1 1 0 CEL-III C-terminal FragX_IP PF05994.11 CDJ54166.1 - 0.26 9.3 0.3 0.31 9.0 0.3 1.0 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family DUF4400 PF14348.6 CDJ54166.1 - 0.27 10.7 1.0 0.36 10.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) RCC_reductase PF06405.11 CDJ54166.1 - 0.29 10.3 6.2 0.42 9.8 6.2 1.2 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) CbiX PF01903.17 CDJ54166.1 - 0.29 11.5 2.5 0.47 10.8 2.5 1.4 1 0 0 1 1 1 0 CbiX CBFD_NFYB_HMF PF00808.23 CDJ54166.1 - 0.62 10.4 8.8 25 5.2 8.8 2.2 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RNase_J_C PF17770.1 CDJ54166.1 - 1.6 9.8 7.2 8.6 7.5 7.2 2.1 1 1 0 1 1 1 0 Ribonuclease J C-terminal domain SecD_SecF PF02355.16 CDJ54166.1 - 1.7 8.0 3.9 3.4 7.0 3.9 1.6 1 1 0 1 1 1 0 Protein export membrane protein Spore_II_R PF09551.10 CDJ54166.1 - 2 8.9 5.0 3.4 8.1 5.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) PGDH_C PF16896.5 CDJ54166.1 - 2.4 8.1 8.9 3.5 7.5 1.5 2.1 1 1 1 2 2 2 0 Phosphogluconate dehydrogenase (decarboxylating) C-term SAC3 PF12209.8 CDJ54166.1 - 4.5 7.5 10.4 3.9e+02 1.3 10.4 2.2 1 1 0 1 1 1 0 Leucine permease transcriptional regulator helical domain Merozoite_SPAM PF07133.11 CDJ54166.1 - 4.7 7.2 28.2 8.2 6.4 28.2 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) YpjP PF14005.6 CDJ54166.1 - 4.8 7.2 10.1 17 5.4 10.1 1.8 1 1 0 1 1 1 0 YpjP-like protein VPR PF00522.18 CDJ54166.1 - 5.2 7.2 7.3 70 3.6 7.3 2.2 1 1 0 1 1 1 0 VPR/VPX protein ARGLU PF15346.6 CDJ54166.1 - 6.4 6.6 23.6 0.17 11.8 16.8 1.7 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 SSPI PF14098.6 CDJ54166.1 - 8.9 6.6 10.3 1.4e+03 -0.5 10.3 2.7 1 1 0 1 1 1 0 Small, acid-soluble spore protein I RRM_1 PF00076.22 CDJ54167.1 - 1.5e-66 220.1 0.0 5.3e-20 71.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CDJ54167.1 - 1.1e-27 96.0 1.8 8.1e-27 93.2 1.9 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 CDJ54167.1 - 0.00068 19.5 0.0 0.097 12.5 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CDJ54167.1 - 0.0061 16.5 0.0 7.1 6.7 0.0 3.6 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CDJ54167.1 - 0.054 13.6 0.1 0.86 9.8 0.0 2.9 3 2 0 3 3 3 0 RNA recognition motif FAM199X PF15814.5 CDJ54167.1 - 4.9 6.1 8.7 10 5.1 8.7 1.5 1 0 0 1 1 1 0 Protein family FAM199X Pex14_N PF04695.13 CDJ54168.1 - 0.0088 16.7 17.0 0.01 16.5 17.0 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PIP5K PF01504.18 CDJ54168.1 - 0.026 13.7 5.9 0.032 13.4 5.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CCDC53 PF10152.9 CDJ54168.1 - 0.036 14.5 12.2 0.049 14.1 12.2 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Baculo_PP31 PF05311.11 CDJ54168.1 - 0.047 13.2 6.5 0.054 13.0 6.5 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Connexin PF00029.19 CDJ54168.1 - 0.052 13.3 4.5 0.052 13.3 4.5 1.1 1 0 0 1 1 1 0 Connexin THOC2_N PF16134.5 CDJ54168.1 - 0.063 11.9 8.7 0.079 11.6 8.7 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Suf PF05843.14 CDJ54168.1 - 0.07 13.1 11.7 0.072 13.1 11.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1980 PF09323.10 CDJ54168.1 - 0.071 13.0 6.2 0.087 12.7 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PAT1 PF09770.9 CDJ54168.1 - 0.075 11.3 17.5 0.072 11.4 17.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PEX11 PF05648.14 CDJ54168.1 - 0.077 12.5 2.3 0.1 12.0 2.3 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Tim54 PF11711.8 CDJ54168.1 - 0.077 11.8 7.0 0.12 11.2 7.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 V_ATPase_I PF01496.19 CDJ54168.1 - 0.14 10.1 8.4 0.13 10.2 8.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ54168.1 - 0.15 10.8 13.9 0.15 10.8 13.9 1.0 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ54168.1 - 0.15 12.0 30.4 0.18 11.8 30.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ54168.1 - 0.16 10.9 12.8 0.15 11.0 12.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MMR1 PF08505.10 CDJ54168.1 - 0.21 11.8 11.8 0.22 11.8 11.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Band_3_cyto PF07565.13 CDJ54168.1 - 0.22 11.3 8.8 0.22 11.3 8.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.17 CDJ54168.1 - 0.33 11.1 10.6 0.38 10.9 10.6 1.1 1 0 0 1 1 1 0 DDHD domain DUF4175 PF13779.6 CDJ54168.1 - 0.42 8.4 26.5 0.44 8.4 26.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EOS1 PF12326.8 CDJ54168.1 - 0.55 10.2 2.8 0.56 10.1 2.8 1.2 1 0 0 1 1 1 0 N-glycosylation protein Neur_chan_memb PF02932.16 CDJ54168.1 - 0.55 10.2 7.2 0.53 10.3 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ54168.1 - 0.96 8.2 5.4 0.87 8.3 5.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 CDJ54168.1 - 1.2 8.3 4.5 1.2 8.2 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0767 PF15990.5 CDJ54168.1 - 1.6 8.9 3.4 6.1 7.1 3.4 1.9 1 1 0 1 1 1 0 UPF0767 family PBP_sp32 PF07222.12 CDJ54168.1 - 1.8 8.0 18.2 2.1 7.7 18.2 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CSG2 PF16965.5 CDJ54168.1 - 1.8 7.4 3.7 1.7 7.5 3.7 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Folate_carrier PF01770.18 CDJ54168.1 - 2.2 6.9 6.0 2.6 6.7 6.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.20 CDJ54168.1 - 2.8 6.1 6.5 3.3 5.9 6.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CLN3 PF02487.17 CDJ54168.1 - 3.5 6.6 8.2 4.5 6.2 8.2 1.1 1 0 0 1 1 1 0 CLN3 protein TERB2 PF15101.6 CDJ54168.1 - 4.2 7.4 17.1 6.8 6.7 17.1 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Hydin_ADK PF17213.3 CDJ54168.1 - 9 6.5 12.8 12 6.1 12.8 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MDM31_MDM32 PF08118.11 CDJ54168.1 - 9.9 4.7 13.4 8.7 4.9 13.0 1.2 1 1 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DAO PF01266.24 CDJ54169.1 - 0.00027 20.7 0.0 0.00031 20.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDJ54169.1 - 0.099 11.7 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 CDJ54169.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain DUF4813 PF16072.5 CDJ54170.1 - 0.76 9.4 34.4 1.1 8.9 34.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) TERB2 PF15101.6 CDJ54170.1 - 1.8 8.6 6.5 2.3 8.3 6.5 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 CDJ54171.1 - 0.00038 19.4 32.5 0.00046 19.1 32.5 1.2 1 0 0 1 1 1 1 Presenilin Lin-8 PF03353.15 CDJ54171.1 - 0.00079 19.1 28.4 0.001 18.7 28.4 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 CDJ54171.1 - 0.0014 17.1 22.0 0.0015 16.9 22.0 1.1 1 0 0 1 1 1 1 CDC45-like protein AAA_11 PF13086.6 CDJ54171.1 - 0.0014 18.5 21.4 0.0019 18.0 21.4 1.3 1 0 0 1 1 1 1 AAA domain DUF572 PF04502.13 CDJ54171.1 - 0.0023 17.6 19.7 0.0025 17.5 19.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) AF-4 PF05110.13 CDJ54171.1 - 0.0034 15.6 28.5 0.0035 15.5 28.5 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein PAT1 PF09770.9 CDJ54171.1 - 0.0044 15.4 47.7 0.0048 15.2 47.7 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Nop53 PF07767.11 CDJ54171.1 - 0.0084 15.5 33.8 0.012 15.1 33.8 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CCSAP PF15748.5 CDJ54171.1 - 0.011 15.9 38.3 0.016 15.4 38.3 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated GAGA_bind PF06217.12 CDJ54171.1 - 0.012 15.9 18.8 0.013 15.8 18.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family LAP1C PF05609.12 CDJ54171.1 - 0.012 14.7 23.2 0.012 14.8 23.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4045 PF13254.6 CDJ54171.1 - 0.013 15.2 24.4 0.014 15.0 24.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF5427 PF10310.9 CDJ54171.1 - 0.024 13.6 31.9 0.04 12.9 31.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) GREB1 PF15782.5 CDJ54171.1 - 0.024 11.8 27.6 0.023 11.8 27.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Raftlin PF15250.6 CDJ54171.1 - 0.027 13.2 18.8 0.029 13.1 18.8 1.2 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.7 CDJ54171.1 - 0.032 12.4 24.9 0.034 12.3 24.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 CDJ54171.1 - 0.033 13.0 19.0 0.036 12.8 19.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CRT10 PF08728.10 CDJ54171.1 - 0.041 12.1 9.0 0.042 12.0 9.0 1.1 1 0 0 1 1 1 0 CRT10 Hamartin PF04388.12 CDJ54171.1 - 0.045 12.4 23.1 0.044 12.5 23.1 1.1 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.13 CDJ54171.1 - 0.048 13.4 18.3 0.048 13.4 18.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Endostatin PF06482.11 CDJ54171.1 - 0.049 13.1 24.3 0.064 12.7 24.3 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Apt1 PF10351.9 CDJ54171.1 - 0.064 12.1 17.2 0.074 11.9 17.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BAF1_ABF1 PF04684.13 CDJ54171.1 - 0.07 12.2 26.5 0.096 11.7 26.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FAM60A PF15396.6 CDJ54171.1 - 0.086 12.8 23.1 0.12 12.3 23.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SRP-alpha_N PF04086.13 CDJ54171.1 - 0.095 12.6 25.2 0.13 12.2 25.2 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Draxin PF15550.6 CDJ54171.1 - 0.13 12.1 20.4 0.19 11.6 20.4 1.2 1 0 0 1 1 1 0 Draxin PPP4R2 PF09184.11 CDJ54171.1 - 0.23 11.0 15.4 0.27 10.8 15.4 1.3 1 0 0 1 1 1 0 PPP4R2 API5 PF05918.11 CDJ54171.1 - 0.28 10.0 25.5 0.37 9.6 25.5 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF4551 PF15087.6 CDJ54171.1 - 0.36 9.6 22.3 0.44 9.3 22.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOG2 PF10428.9 CDJ54171.1 - 0.39 9.9 29.4 0.49 9.5 29.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SID-1_RNA_chan PF13965.6 CDJ54171.1 - 0.47 8.8 12.7 0.59 8.5 12.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2151 PF10221.9 CDJ54171.1 - 0.52 8.9 15.3 0.6 8.6 15.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator GPCR_chapero_1 PF11904.8 CDJ54171.1 - 0.66 9.4 17.9 0.78 9.1 17.9 1.3 1 0 0 1 1 1 0 GPCR-chaperone WTX PF09422.10 CDJ54171.1 - 0.67 9.0 22.3 0.92 8.5 22.3 1.3 1 0 0 1 1 1 0 WTX protein NPR3 PF03666.13 CDJ54171.1 - 0.89 8.3 31.5 1.4 7.7 31.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1387 PF07139.11 CDJ54171.1 - 0.9 9.2 28.2 1.4 8.5 28.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) 5_nucleotid PF05761.14 CDJ54171.1 - 1 8.2 16.8 1.3 7.9 16.8 1.4 1 0 0 1 1 1 0 5' nucleotidase family SAGA-Tad1 PF12767.7 CDJ54171.1 - 1.1 9.0 27.2 1.5 8.5 27.2 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit HAUS6_N PF14661.6 CDJ54171.1 - 1.2 8.6 28.9 1.7 8.2 28.9 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RR_TM4-6 PF06459.12 CDJ54171.1 - 1.2 8.9 36.8 2.2 8.0 36.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ54171.1 - 1.5 7.8 34.7 2.1 7.3 34.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 CDJ54171.1 - 1.7 7.5 22.4 2.1 7.1 22.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CAF1 PF04857.20 CDJ54171.1 - 1.8 7.6 18.2 2.3 7.3 18.2 1.4 1 0 0 1 1 1 0 CAF1 family ribonuclease CDK5_activator PF03261.15 CDJ54171.1 - 2.1 7.8 22.1 2.3 7.7 22.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Smg8_Smg9 PF10220.9 CDJ54171.1 - 2.5 6.3 29.3 3.2 6.0 29.3 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Pkinase_fungal PF17667.1 CDJ54171.1 - 7.4 5.2 17.1 9.2 4.9 17.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Sin_N PF04801.13 CDJ54171.1 - 7.5 5.6 45.7 11 5.1 45.7 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region DAG_kinase_N PF14513.6 CDJ54171.1 - 7.8 6.7 29.7 15 5.8 29.7 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus NPV_P10 PF05531.12 CDJ54172.1 - 3.8 8.1 18.0 25 5.4 0.4 5.3 2 2 4 6 6 6 0 Nucleopolyhedrovirus P10 protein SET PF00856.28 CDJ54173.1 - 8.7e-09 36.0 0.1 4e-07 30.6 0.0 3.0 2 2 1 3 3 3 1 SET domain zf-MYND PF01753.18 CDJ54173.1 - 4.9e-07 29.7 17.3 4.9e-07 29.7 17.3 2.9 3 1 0 3 3 3 1 MYND finger Ribophorin_I PF04597.14 CDJ54174.1 - 7.2e-61 206.7 0.0 1e-51 176.6 0.0 2.2 2 0 0 2 2 2 2 Ribophorin I DEAD PF00270.29 CDJ54178.1 - 2.4e-14 53.5 0.1 4.8e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ54178.1 - 0.00014 21.9 1.4 0.00026 21.0 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit FAM60A PF15396.6 CDJ54178.1 - 0.69 9.9 5.8 0.77 9.7 5.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF4813 PF16072.5 CDJ54178.1 - 1.6 8.3 23.3 2.3 7.8 23.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) GREB1 PF15782.5 CDJ54178.1 - 2.2 5.3 5.4 2.3 5.2 5.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AIF-MLS PF14962.6 CDJ54178.1 - 3.2 7.7 24.0 5 7.0 24.0 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Ndc1_Nup PF09531.10 CDJ54178.1 - 3.5 6.2 6.6 3.4 6.2 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CDJ54178.1 - 4.3 6.0 7.9 4.5 5.9 7.9 1.2 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 CDJ54178.1 - 6 5.6 7.0 6.9 5.4 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ALMT PF11744.8 CDJ54178.1 - 7.2 5.3 9.1 8.8 5.0 9.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MCR PF18509.1 CDJ54179.1 - 0.2 11.3 0.2 0.39 10.3 0.2 1.4 1 0 0 1 1 1 0 Magnetochrome domain Subtilosin_A PF11420.8 CDJ54179.1 - 0.64 10.0 4.5 6.6 6.8 0.9 2.8 2 0 0 2 2 2 0 Bacteriocin subtilosin A DUF4657 PF15552.6 CDJ54181.1 - 0.089 12.3 10.4 0.1 12.2 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) UPF0565 PF10561.9 CDJ54181.1 - 0.1 11.8 3.3 0.12 11.6 3.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 BRF1 PF07741.13 CDJ54181.1 - 0.13 12.6 1.0 0.15 12.4 1.0 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4366 PF14283.6 CDJ54181.1 - 0.37 10.8 2.2 0.47 10.5 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3573 PF12097.8 CDJ54181.1 - 1.1 7.9 3.0 1.1 8.0 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Spt20 PF12090.8 CDJ54181.1 - 2.7 7.5 8.5 3 7.4 8.5 1.1 1 0 0 1 1 1 0 Spt20 family SNF2_N PF00176.23 CDJ54182.1 - 4.3e-14 52.0 1.9 4.4e-13 48.7 0.1 2.2 1 1 1 2 2 2 1 SNF2 family N-terminal domain CCDC117 PF15810.5 CDJ54182.1 - 0.079 13.3 3.6 8.5 6.7 0.0 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 117 Draxin PF15550.6 CDJ54182.1 - 0.3 10.9 4.7 0.15 11.9 2.9 1.3 2 0 0 2 2 2 0 Draxin DUF2407 PF10302.9 CDJ54182.1 - 0.35 11.5 1.5 14 6.3 0.0 2.3 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Ndc1_Nup PF09531.10 CDJ54182.1 - 2.6 6.6 11.2 3.2 6.4 11.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 CDJ54182.1 - 3 7.4 21.6 0.21 11.2 12.8 2.1 2 0 0 2 2 2 0 Spt20 family DUF4770 PF15994.5 CDJ54182.1 - 3.4 7.9 8.7 0.98 9.6 5.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF4834 PF16118.5 CDJ54182.1 - 5.5 8.0 5.8 10 7.2 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ELO PF01151.18 CDJ54185.1 - 2.5e-05 24.0 0.0 2.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Zip PF02535.22 CDJ54185.1 - 0.19 10.9 0.6 0.28 10.4 0.6 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter CTU2 PF10288.9 CDJ54185.1 - 3.7 7.8 6.6 40 4.5 0.0 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Spt20 PF12090.8 CDJ54185.1 - 5.9 6.4 12.5 8.8 5.9 12.5 1.2 1 0 0 1 1 1 0 Spt20 family Fer4_24 PF18109.1 CDJ54186.1 - 0.097 13.0 0.3 0.097 13.0 0.3 1.8 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain TIP49 PF06068.13 CDJ54187.1 - 2.8e-29 102.4 0.1 3.8e-29 102.0 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CDJ54187.1 - 1.4e-19 70.0 0.0 2.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 AAA-lid domain TFIIA PF03153.13 CDJ54190.1 - 0.0015 18.6 3.7 0.0015 18.6 3.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit E_Pc_C PF06752.12 CDJ54190.1 - 0.0058 16.8 6.9 0.0076 16.4 6.9 1.2 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus Ribosomal_60s PF00428.19 CDJ54190.1 - 0.017 15.7 13.5 0.031 14.8 13.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ54190.1 - 0.051 13.2 10.8 0.081 12.5 10.8 1.4 1 0 0 1 1 1 0 Spt20 family RLL PF10036.9 CDJ54190.1 - 0.14 12.0 2.2 0.18 11.6 2.2 1.2 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein FTZ PF03867.14 CDJ54190.1 - 1.1 8.7 7.6 1.8 8.0 7.6 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region RSRP PF17069.5 CDJ54191.1 - 0.0094 15.6 0.2 0.024 14.2 0.2 1.7 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 Reovirus_cap PF00979.17 CDJ54191.1 - 0.05 12.8 0.1 0.091 11.9 0.1 1.3 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 SARAF PF06682.12 CDJ54191.1 - 0.059 13.0 4.9 0.1 12.3 4.9 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF5349 PF17298.2 CDJ54191.1 - 1.4 8.6 5.5 3.3 7.4 5.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5349) PAT1 PF09770.9 CDJ54191.1 - 1.6 6.9 13.1 2.3 6.4 13.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.9 CDJ54192.1 - 4.9e-06 26.3 12.5 8.6e-06 25.5 12.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Dsh_C PF12316.8 CDJ54192.1 - 0.012 16.0 13.1 0.018 15.5 13.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF1631 PF07793.11 CDJ54192.1 - 0.063 11.7 6.6 0.079 11.4 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) PIP5K PF01504.18 CDJ54193.1 - 0.0061 15.8 1.0 0.0061 15.8 1.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Band_3_cyto PF07565.13 CDJ54193.1 - 8.9 6.0 38.6 1.6 8.5 16.3 3.2 3 0 0 3 3 3 0 Band 3 cytoplasmic domain Spt20 PF12090.8 CDJ54196.1 - 0.013 15.1 12.5 0.018 14.7 12.5 1.3 1 0 0 1 1 1 0 Spt20 family IMUP PF15761.5 CDJ54196.1 - 0.26 12.0 8.6 0.48 11.1 2.1 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein CCDC53 PF10152.9 CDJ54196.1 - 1.2 9.5 9.9 0.1 13.0 3.6 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TFIIA PF03153.13 CDJ54196.1 - 2.9 7.8 16.5 3.6 7.5 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM208_SND2 PF05620.11 CDJ54196.1 - 9.6 6.0 7.7 15 5.3 0.1 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 PepSY_2 PF13670.6 CDJ54196.1 - 9.8 6.3 11.2 1.1 9.4 2.9 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain TFIIA PF03153.13 CDJ54197.1 - 0.48 10.4 77.2 10 6.0 49.4 2.5 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 CDJ54198.1 - 0.024 13.0 21.1 0.031 12.6 21.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ54198.1 - 0.26 10.2 25.4 0.38 9.7 25.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 CDJ54198.1 - 0.78 8.5 19.6 1.1 7.9 19.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3474 PF11960.8 CDJ54198.1 - 1.8 8.7 9.3 0.89 9.8 5.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) DUF2151 PF10221.9 CDJ54198.1 - 3.6 6.1 14.3 4.5 5.7 14.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Apt1 PF10351.9 CDJ54198.1 - 4.8 5.9 21.2 6 5.6 21.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2052 PF09747.9 CDJ54198.1 - 8.4 6.5 35.2 2.9 8.0 23.6 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4551 PF15087.6 CDJ54198.1 - 8.8 5.0 31.9 11 4.7 31.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4179 PF13786.6 CDJ54199.1 - 0.0046 17.4 3.8 1.1 9.8 0.5 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4179) RskA PF10099.9 CDJ54199.1 - 0.0098 16.2 36.0 0.12 12.7 9.8 2.5 2 1 0 2 2 2 2 Anti-sigma-K factor rskA Shadoo PF14999.6 CDJ54199.1 - 1.6 8.8 15.2 0.89 9.6 5.1 2.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective RR_TM4-6 PF06459.12 CDJ54199.1 - 2.4 7.9 31.1 0.22 11.3 22.7 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Hamartin PF04388.12 CDJ54199.1 - 3.4 6.2 27.0 4.4 5.8 27.0 1.1 1 0 0 1 1 1 0 Hamartin protein IHABP4_N PF16174.5 CDJ54199.1 - 4 8.0 43.0 4.9 7.7 33.6 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Holin_BhlA PF10960.8 CDJ54200.1 - 1.6 8.8 4.2 4.2 7.4 4.2 1.7 1 0 0 1 1 1 0 BhlA holin family SWIRM-assoc_1 PF16495.5 CDJ54202.1 - 0.04 13.9 0.1 0.089 12.8 0.1 1.5 1 0 0 1 1 1 0 SWIRM-associated region 1 F-box-like PF12937.7 CDJ54203.1 - 0.17 11.8 0.9 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 F-box-like HABP4_PAI-RBP1 PF04774.15 CDJ54204.1 - 0.0046 17.8 2.6 0.0051 17.6 2.6 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Med19 PF10278.9 CDJ54204.1 - 0.005 16.8 1.4 0.0059 16.6 1.4 1.0 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 Spt20 PF12090.8 CDJ54204.1 - 0.008 15.8 19.8 0.0083 15.8 19.8 1.1 1 0 0 1 1 1 1 Spt20 family MT-A70 PF05063.14 CDJ54204.1 - 0.012 15.5 1.5 0.014 15.3 0.0 1.7 2 0 0 2 2 2 0 MT-A70 DUF4834 PF16118.5 CDJ54204.1 - 0.038 14.9 5.2 0.037 15.0 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ54204.1 - 0.055 13.5 15.9 0.053 13.5 15.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CDJ54204.1 - 0.075 12.0 24.7 0.076 12.0 24.7 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF775 PF05603.12 CDJ54204.1 - 0.1 12.2 5.9 0.11 12.1 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) OrfB_IS605 PF01385.19 CDJ54204.1 - 0.23 11.7 3.4 0.27 11.4 3.4 1.1 1 0 0 1 1 1 0 Probable transposase EIIBC-GUT_N PF03612.14 CDJ54204.1 - 0.25 11.1 3.3 0.26 11.0 3.3 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pex26 PF07163.12 CDJ54204.1 - 0.4 9.9 8.2 0.49 9.7 8.2 1.1 1 0 0 1 1 1 0 Pex26 protein Suf PF05843.14 CDJ54204.1 - 0.67 9.9 8.6 0.69 9.8 8.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2722 PF10846.8 CDJ54204.1 - 0.77 8.6 19.9 0.87 8.5 19.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 CDJ54204.1 - 0.86 8.5 9.1 0.85 8.5 9.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.6 CDJ54204.1 - 1 7.2 17.1 1.1 7.1 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UPF0560 PF10577.9 CDJ54204.1 - 1.3 7.4 10.9 1.3 7.5 10.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Presenilin PF01080.17 CDJ54204.1 - 1.5 7.5 5.5 1.5 7.5 5.5 1.0 1 0 0 1 1 1 0 Presenilin Med3 PF11593.8 CDJ54204.1 - 1.7 7.7 15.7 2.2 7.4 15.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3464 PF11947.8 CDJ54204.1 - 1.7 8.4 5.9 2.1 8.1 5.9 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4710 PF15828.5 CDJ54204.1 - 2.7 8.2 5.5 3.7 7.7 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Roughex PF06020.11 CDJ54204.1 - 3.1 6.8 10.1 2.9 6.9 10.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein MRP-S27 PF10037.9 CDJ54204.1 - 3.9 6.2 12.3 4.4 6.1 12.3 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Androgen_recep PF02166.16 CDJ54204.1 - 4 6.2 19.6 4.3 6.1 19.6 1.0 1 0 0 1 1 1 0 Androgen receptor Pex14_N PF04695.13 CDJ54205.1 - 0.053 14.2 26.2 0.067 13.8 26.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.14 CDJ54205.1 - 0.072 11.4 19.5 0.088 11.1 19.5 1.0 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 CDJ54205.1 - 0.24 11.3 21.7 0.3 11.0 21.7 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Sin_N PF04801.13 CDJ54205.1 - 0.25 10.5 28.1 0.28 10.3 28.1 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Mgr1 PF08602.10 CDJ54205.1 - 0.34 9.7 7.9 0.41 9.4 7.9 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit SpoIIP PF07454.11 CDJ54205.1 - 0.38 10.2 17.9 0.42 10.0 17.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDJ54205.1 - 0.42 10.4 21.9 0.51 10.1 21.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CAC1F_C PF16885.5 CDJ54205.1 - 0.55 9.8 14.3 0.62 9.7 14.3 1.0 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term CCSAP PF15748.5 CDJ54205.1 - 0.8 9.8 21.9 0.85 9.7 21.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Tim54 PF11711.8 CDJ54205.1 - 0.85 8.3 14.8 0.98 8.1 14.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CCDC53 PF10152.9 CDJ54205.1 - 1 9.8 18.8 1.3 9.4 18.8 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF913 PF06025.12 CDJ54205.1 - 1.1 8.1 11.0 1.2 8.1 11.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CDJ54205.1 - 1.2 7.8 23.9 1.3 7.7 23.9 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CDJ54205.1 - 1.3 7.7 17.9 1.3 7.7 17.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Bul1_N PF04425.12 CDJ54205.1 - 1.7 7.3 14.9 1.8 7.2 14.9 1.0 1 0 0 1 1 1 0 Bul1 N terminus DUF2052 PF09747.9 CDJ54205.1 - 1.8 8.6 22.4 2.3 8.3 22.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Gti1_Pac2 PF09729.9 CDJ54205.1 - 2.3 8.3 16.4 2.5 8.2 16.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DDHD PF02862.17 CDJ54205.1 - 2.4 8.3 17.0 3.2 7.8 17.0 1.3 1 0 0 1 1 1 0 DDHD domain OATP PF03137.20 CDJ54205.1 - 2.9 6.1 10.1 3.6 5.8 10.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Afi1 PF07792.12 CDJ54205.1 - 3 8.3 16.2 4.7 7.7 16.2 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking ALMT PF11744.8 CDJ54205.1 - 3.1 6.5 16.2 3.4 6.4 16.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Connexin PF00029.19 CDJ54205.1 - 3.4 7.4 14.4 4.6 6.9 14.4 1.3 1 0 0 1 1 1 0 Connexin TFIIA PF03153.13 CDJ54205.1 - 3.5 7.5 46.1 4.8 7.1 46.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ54205.1 - 3.6 6.5 25.1 4 6.3 25.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ54205.1 - 4.3 6.3 21.2 4.6 6.2 21.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 BORG_CEP PF14957.6 CDJ54205.1 - 4.7 8.4 13.2 5.8 8.1 13.2 1.2 1 0 0 1 1 1 0 Cdc42 effector PAT1 PF09770.9 CDJ54205.1 - 4.9 5.3 34.2 5.2 5.2 34.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CSG2 PF16965.5 CDJ54205.1 - 5.1 5.9 11.5 5.9 5.7 11.5 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator SprA-related PF12118.8 CDJ54205.1 - 6.2 5.9 45.9 6.8 5.7 45.9 1.0 1 0 0 1 1 1 0 SprA-related family DUF2370 PF10176.9 CDJ54205.1 - 6.5 6.3 9.4 7.4 6.2 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Hid1 PF12722.7 CDJ54205.1 - 6.5 4.7 18.7 7.1 4.6 18.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ureide_permease PF07168.11 CDJ54205.1 - 7.3 5.2 7.9 8.8 5.0 7.9 1.3 1 0 0 1 1 1 0 Ureide permease HGTP_anticodon2 PF12745.7 CDJ54205.1 - 7.7 5.9 20.7 9.1 5.7 20.7 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Peptidase_S15 PF02129.18 CDJ54205.1 - 7.8 6.0 14.0 11 5.5 14.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PPL5 PF18168.1 CDJ54205.1 - 8.2 5.6 12.8 9.9 5.4 12.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF853 PF05872.12 CDJ54205.1 - 8.8 4.8 16.1 11 4.5 16.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) CLN3 PF02487.17 CDJ54205.1 - 9 5.2 17.1 11 5.0 17.1 1.0 1 0 0 1 1 1 0 CLN3 protein Peptidase_S64 PF08192.11 CDJ54205.1 - 9.2 4.6 17.6 10 4.5 17.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Membralin PF09746.9 CDJ54205.1 - 9.6 5.1 14.3 10 5.0 14.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein YABBY PF04690.13 CDJ54205.1 - 9.9 6.7 15.5 11 6.5 15.5 1.3 1 0 0 1 1 1 0 YABBY protein zf-RVT PF13966.6 CDJ54207.1 - 0.00076 20.1 0.1 0.002 18.8 0.1 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ54208.1 - 8.9e-09 35.3 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ54208.1 - 0.03 14.6 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase SWI-SNF_Ssr4 PF08549.10 CDJ54211.1 - 0.81 8.3 6.9 0.93 8.0 6.9 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Connexin PF00029.19 CDJ54213.1 - 0.11 12.2 7.0 0.11 12.2 7.0 1.2 1 0 0 1 1 1 0 Connexin SpoIIP PF07454.11 CDJ54213.1 - 0.13 11.7 12.5 0.14 11.6 12.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) XAP5 PF04921.14 CDJ54213.1 - 0.29 10.9 9.1 0.32 10.8 9.1 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator Peroxin-13_N PF04088.13 CDJ54213.1 - 0.45 10.8 5.1 0.6 10.4 5.1 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FAM176 PF14851.6 CDJ54213.1 - 0.49 10.0 6.9 0.57 9.8 6.9 1.2 1 0 0 1 1 1 0 FAM176 family CSG2 PF16965.5 CDJ54213.1 - 0.53 9.2 2.8 0.52 9.2 2.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator CPSF100_C PF13299.6 CDJ54213.1 - 0.53 10.4 12.5 0.58 10.3 12.5 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Paf1 PF03985.13 CDJ54213.1 - 0.55 9.2 14.6 0.76 8.7 14.6 1.2 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 CDJ54213.1 - 0.56 8.9 15.7 0.6 8.8 15.7 1.0 1 0 0 1 1 1 0 Presenilin UNC-79 PF14776.6 CDJ54213.1 - 0.61 8.8 5.9 0.72 8.5 5.9 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 DUF4834 PF16118.5 CDJ54213.1 - 0.71 10.9 20.9 0.054 14.5 14.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TFB6 PF17110.5 CDJ54213.1 - 0.78 9.5 6.1 0.79 9.4 6.1 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PIP5K PF01504.18 CDJ54213.1 - 0.81 8.9 9.1 0.8 8.9 9.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CLN3 PF02487.17 CDJ54213.1 - 0.92 8.5 7.9 0.82 8.7 7.9 1.1 1 0 0 1 1 1 0 CLN3 protein Maf1 PF09174.10 CDJ54213.1 - 0.95 9.6 8.6 1.1 9.3 8.6 1.2 1 0 0 1 1 1 0 Maf1 regulator CobT PF06213.12 CDJ54213.1 - 1.1 8.6 21.3 1.3 8.4 21.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Band_3_cyto PF07565.13 CDJ54213.1 - 1.1 9.0 13.3 1.2 8.9 13.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ureide_permease PF07168.11 CDJ54213.1 - 1.1 7.9 3.2 1.2 7.8 3.2 1.1 1 0 0 1 1 1 0 Ureide permease DUF2828 PF11443.8 CDJ54213.1 - 1.1 7.2 9.4 1.1 7.3 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DDHD PF02862.17 CDJ54213.1 - 1.3 9.1 12.0 1.4 9.0 12.0 1.2 1 0 0 1 1 1 0 DDHD domain DUF4746 PF15928.5 CDJ54213.1 - 1.4 8.3 8.6 1.4 8.3 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 CDJ54213.1 - 1.4 8.7 12.4 1.5 8.6 12.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EFTUD2 PF16004.5 CDJ54213.1 - 1.5 9.4 17.9 2 9.0 17.9 1.4 1 1 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Tim54 PF11711.8 CDJ54213.1 - 1.5 7.5 11.9 1.6 7.4 11.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.8 CDJ54213.1 - 1.5 7.7 13.4 1.6 7.6 13.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4770 PF15994.5 CDJ54213.1 - 1.5 9.0 19.3 1.9 8.7 19.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Gti1_Pac2 PF09729.9 CDJ54213.1 - 1.5 8.9 10.4 1.8 8.7 10.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 CDJ54213.1 - 1.5 7.7 13.1 1.6 7.6 13.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Folate_carrier PF01770.18 CDJ54213.1 - 1.8 7.2 6.3 2 7.1 6.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.20 CDJ54213.1 - 1.9 6.7 7.3 1.6 6.9 7.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EOS1 PF12326.8 CDJ54213.1 - 1.9 8.4 5.8 1.9 8.4 5.8 1.2 1 0 0 1 1 1 0 N-glycosylation protein Cellulose_synt PF03552.14 CDJ54213.1 - 1.9 6.8 3.5 2.1 6.7 3.5 1.0 1 0 0 1 1 1 0 Cellulose synthase G0-G1_switch_2 PF15103.6 CDJ54213.1 - 2.4 8.6 10.5 0.85 10.1 8.0 1.5 2 0 0 2 2 1 0 G0/G1 switch protein 2 Peptidase_U57 PF05582.12 CDJ54213.1 - 2.4 7.3 8.5 3.1 7.0 8.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Ctr PF04145.15 CDJ54213.1 - 2.7 8.6 8.1 2.9 8.5 8.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family PepSY_TM PF03929.16 CDJ54213.1 - 2.7 7.6 8.1 2.5 7.7 8.1 1.1 1 0 0 1 1 1 0 PepSY-associated TM region eIF-3_zeta PF05091.12 CDJ54213.1 - 2.7 6.9 20.2 2.8 6.8 20.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sec62 PF03839.16 CDJ54213.1 - 3.3 7.2 8.8 3.5 7.1 8.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Het-C PF07217.11 CDJ54213.1 - 3.9 5.9 8.4 3.9 5.9 8.4 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Serinc PF03348.15 CDJ54213.1 - 4.2 6.2 7.0 3.9 6.3 7.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.6 CDJ54213.1 - 4.2 5.7 5.3 3.8 5.8 5.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FHIPEP PF00771.20 CDJ54213.1 - 4.3 5.7 8.7 4.1 5.7 8.7 1.1 1 0 0 1 1 1 0 FHIPEP family MDM10 PF12519.8 CDJ54213.1 - 4.5 6.0 12.2 4.8 5.9 12.2 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Kei1 PF08552.11 CDJ54213.1 - 4.7 7.1 7.9 4.9 7.0 7.9 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Pex14_N PF04695.13 CDJ54213.1 - 5.1 7.7 28.8 7.2 7.2 28.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4199 PF13858.6 CDJ54213.1 - 7.9 6.9 6.7 7.6 6.9 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ALMT PF11744.8 CDJ54213.1 - 8.1 5.1 10.0 7.7 5.2 10.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 CDJ54213.1 - 9.5 6.2 13.3 10 6.1 13.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 CDJ54213.1 - 9.8 4.2 12.8 9.2 4.2 12.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SR-25 PF10500.9 CDJ54214.1 - 0.012 15.3 14.8 0.018 14.7 14.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ54214.1 - 0.03 14.2 1.2 0.033 14.1 1.2 1.1 1 0 0 1 1 1 0 SPX domain Lin-8 PF03353.15 CDJ54214.1 - 0.29 10.7 1.4 0.32 10.5 1.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AF-4 PF05110.13 CDJ54214.1 - 8.8 4.3 16.7 10 4.1 16.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TMEM171 PF15471.6 CDJ54215.1 - 0.16 11.0 6.9 0.25 10.3 6.9 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 FHIPEP PF00771.20 CDJ54215.1 - 0.72 8.2 4.0 1.4 7.3 4.0 1.4 1 0 0 1 1 1 0 FHIPEP family FAM199X PF15814.5 CDJ54216.1 - 0.31 10.1 7.4 0.33 10.0 7.4 1.0 1 0 0 1 1 1 0 Protein family FAM199X DUF4179 PF13786.6 CDJ54216.1 - 0.5 10.9 5.2 0.65 10.5 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF2232 PF09991.9 CDJ54216.1 - 1.3 8.1 2.9 1.4 8.0 2.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Ribosomal_L37 PF08561.10 CDJ54216.1 - 2 9.0 12.7 2.2 8.8 12.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 TFIIA PF03153.13 CDJ54216.1 - 3.4 7.5 25.3 3.6 7.5 25.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dehydrin PF00257.19 CDJ54216.1 - 3.6 8.1 5.8 3.8 8.1 5.8 1.1 1 0 0 1 1 1 0 Dehydrin R_equi_Vir PF05526.11 CDJ54216.1 - 9 6.1 11.4 10 6.0 11.4 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Ras PF00071.22 CDJ54217.1 - 1e-18 67.5 0.6 1e-18 67.5 0.6 2.2 2 1 0 2 2 1 1 Ras family Roc PF08477.13 CDJ54217.1 - 5.6e-06 26.6 5.9 1.1e-05 25.7 0.0 2.7 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CDJ54217.1 - 3.8e-05 23.3 0.1 3.8e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain API5 PF05918.11 CDJ54217.1 - 0.0046 15.8 13.7 0.0046 15.8 13.7 1.7 1 1 1 2 2 2 1 Apoptosis inhibitory protein 5 (API5) Pex14_N PF04695.13 CDJ54217.1 - 0.018 15.7 25.0 0.041 14.5 15.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ54217.1 - 0.034 13.7 40.4 0.18 11.4 28.0 2.1 2 0 0 2 2 2 0 Spt20 family DUF5327 PF17261.2 CDJ54217.1 - 0.038 14.7 22.1 0.19 12.5 1.7 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF2935 PF11155.8 CDJ54217.1 - 0.046 14.1 3.4 1.2 9.5 3.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Trp_oprn_chp PF09534.10 CDJ54217.1 - 0.057 13.2 11.9 0.036 13.9 4.2 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) IHABP4_N PF16174.5 CDJ54217.1 - 0.091 13.4 23.4 1.2 9.7 2.6 2.1 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal RAB3GAP2_N PF14655.6 CDJ54217.1 - 0.16 11.2 11.7 0.15 11.3 5.4 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus N6_N4_Mtase PF01555.18 CDJ54217.1 - 0.19 11.4 2.1 0.31 10.7 1.4 1.6 1 1 0 1 1 1 0 DNA methylase EphA2_TM PF14575.6 CDJ54217.1 - 0.25 12.3 5.0 2.1 9.3 2.3 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4179 PF13786.6 CDJ54217.1 - 0.35 11.4 4.7 0.46 11.0 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Stevor PF17410.2 CDJ54217.1 - 0.44 10.0 3.9 0.39 10.2 2.6 1.5 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4834 PF16118.5 CDJ54217.1 - 0.46 11.5 14.7 4.1 8.4 9.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) AIF_C PF14721.6 CDJ54217.1 - 1.2 9.5 14.3 10 6.5 0.2 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Band_3_cyto PF07565.13 CDJ54217.1 - 1.5 8.6 10.6 1.4 8.6 5.5 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FHIPEP PF00771.20 CDJ54217.1 - 1.5 7.1 12.1 0.36 9.2 6.4 2.0 2 0 0 2 2 2 0 FHIPEP family RsgA_GTPase PF03193.16 CDJ54217.1 - 1.7 8.5 5.2 18 5.2 0.3 3.0 2 1 1 3 3 3 0 RsgA GTPase CPSF100_C PF13299.6 CDJ54217.1 - 1.8 8.7 13.4 1.3 9.2 6.6 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal ATAD4 PF15321.6 CDJ54217.1 - 1.8 9.9 9.6 8.6 7.8 3.7 2.3 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Peroxin-13_N PF04088.13 CDJ54217.1 - 2.1 8.6 8.2 1.1 9.5 3.8 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region EIIBC-GUT_N PF03612.14 CDJ54217.1 - 2.6 7.8 16.6 2.2 8.0 1.0 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4820 PF16091.5 CDJ54217.1 - 2.8 7.3 12.3 0.8 9.0 5.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RskA PF10099.9 CDJ54217.1 - 3.3 8.0 37.8 1.3e+02 2.8 37.8 2.2 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Rxt3 PF08642.10 CDJ54217.1 - 3.8 8.3 6.9 9.3 7.0 2.9 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF1980 PF09323.10 CDJ54217.1 - 3.8 7.4 10.6 18 5.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) TERB2 PF15101.6 CDJ54217.1 - 4 7.5 19.7 5.4 7.0 12.5 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Dehydrin PF00257.19 CDJ54217.1 - 4.5 7.8 12.3 15 6.1 5.8 2.2 2 0 0 2 2 2 0 Dehydrin GOLD_2 PF13897.6 CDJ54217.1 - 4.6 7.7 5.5 3.5 8.1 1.5 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF3371 PF11851.8 CDJ54217.1 - 6.4 7.9 19.7 5.1 8.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) GREB1 PF15782.5 CDJ54217.1 - 7 3.6 17.0 8.8 3.3 17.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LMBR1 PF04791.16 CDJ54217.1 - 9.9 4.9 9.6 12 4.6 9.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Glyco_hydro_9 PF00759.19 CDJ54219.1 - 0.29 10.5 6.1 0.32 10.4 6.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Polyoma_coat2 PF00761.20 CDJ54219.1 - 0.77 9.4 5.7 0.096 12.4 1.5 1.6 1 1 1 2 2 2 0 Polyomavirus coat protein SR-25 PF10500.9 CDJ54220.1 - 0.014 15.0 37.9 0.033 13.8 37.9 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ54220.1 - 0.8 10.3 28.2 1 9.9 28.2 1.1 1 0 0 1 1 1 0 TCP family transcription factor SelP_N PF04592.14 CDJ54220.1 - 2 7.7 23.2 2.5 7.4 23.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region eIF-3_zeta PF05091.12 CDJ54220.1 - 4 6.3 29.2 4.4 6.2 29.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DREPP PF05558.12 CDJ54220.1 - 4.7 7.1 7.3 4.8 7.0 7.3 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide DUF1980 PF09323.10 CDJ54220.1 - 5.7 6.8 16.7 7.5 6.4 16.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CCSAP PF15748.5 CDJ54220.1 - 5.8 7.0 37.3 7 6.7 37.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ54220.1 - 6 6.6 27.2 7.1 6.4 27.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 CDJ54220.1 - 6.5 6.3 18.3 7.8 6.0 18.3 1.1 1 0 0 1 1 1 0 PPP4R2 DUF2126 PF09899.9 CDJ54220.1 - 6.7 4.6 15.1 6.6 4.7 15.1 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Peptidase_S64 PF08192.11 CDJ54220.1 - 7.1 5.0 23.2 9.2 4.6 23.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF4746 PF15928.5 CDJ54220.1 - 7.1 6.0 14.9 8.3 5.7 14.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NARP1 PF12569.8 CDJ54220.1 - 7.4 5.4 20.6 7.4 5.3 20.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Asp-B-Hydro_N PF05279.11 CDJ54220.1 - 9.2 6.2 16.0 10 6.1 16.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2828 PF11443.8 CDJ54220.1 - 9.4 4.2 19.6 10 4.1 19.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Endostatin PF06482.11 CDJ54220.1 - 9.8 5.5 24.2 12 5.3 24.2 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF2721 PF11026.8 CDJ54221.1 - 0.0073 16.2 2.0 0.0073 16.2 2.0 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2721) DUF2722 PF10846.8 CDJ54221.1 - 0.01 14.9 11.5 0.012 14.6 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ54221.1 - 0.014 15.1 13.2 0.014 15.0 13.2 1.1 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CDJ54221.1 - 0.17 12.8 2.8 0.21 12.6 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ54221.1 - 0.36 10.8 20.0 0.37 10.7 20.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BRF1 PF07741.13 CDJ54221.1 - 0.37 11.1 6.3 0.5 10.7 6.3 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Pex14_N PF04695.13 CDJ54221.1 - 0.46 11.1 12.3 0.57 10.8 12.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CDJ54221.1 - 0.51 10.3 7.5 0.53 10.2 7.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ54221.1 - 0.58 8.9 4.7 0.54 9.0 4.7 1.1 1 0 0 1 1 1 0 Presenilin G0-G1_switch_2 PF15103.6 CDJ54221.1 - 0.58 10.6 4.5 0.77 10.2 4.5 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 Baculo_PP31 PF05311.11 CDJ54221.1 - 0.63 9.5 4.8 0.71 9.3 4.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Neur_chan_memb PF02932.16 CDJ54221.1 - 1.4 9.0 3.9 1.4 9.0 3.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RTX PF02382.15 CDJ54221.1 - 1.9 8.1 13.6 2.1 8.0 13.6 1.0 1 0 0 1 1 1 0 N-terminal domain in RTX protein DUF4179 PF13786.6 CDJ54221.1 - 2.8 8.5 6.3 0.46 11.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Activator_LAG-3 PF11498.8 CDJ54221.1 - 3.3 6.6 26.4 4.2 6.2 26.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4781 PF16013.5 CDJ54221.1 - 5 5.8 11.3 7.1 5.3 11.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4781) PDEase_I PF00233.19 CDJ54222.1 - 1.1e-25 90.7 0.0 1.1e-25 90.7 0.0 3.8 2 2 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase 14-3-3 PF00244.20 CDJ54223.1 - 4.1e-25 88.6 0.3 2.2e-17 63.3 0.1 3.3 2 1 0 2 2 2 2 14-3-3 protein LSDAT_euk PF18139.1 CDJ54223.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 2 0 0 2 2 2 0 SLOG in TRPM SecY PF00344.20 CDJ54224.1 - 2.7e-71 240.3 15.8 3.3e-71 240.1 15.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CDJ54224.1 - 9.4e-18 63.8 1.1 2.2e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p DUF4746 PF15928.5 CDJ54225.1 - 0.84 9.0 12.9 1 8.7 12.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FancD2 PF14631.6 CDJ54225.1 - 2.1 5.6 3.6 2.5 5.4 3.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease TRAP_alpha PF03896.16 CDJ54225.1 - 7.2 5.7 7.2 8.5 5.5 7.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRM_1 PF00076.22 CDJ54226.1 - 1e-35 121.4 0.0 5.6e-19 67.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDJ54226.1 - 0.00037 20.5 0.0 0.55 10.4 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.11 CDJ54226.1 - 0.00099 19.1 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif YflT PF11181.8 CDJ54226.1 - 0.13 12.8 0.1 6.5 7.3 0.1 2.8 3 0 0 3 3 3 0 Heat induced stress protein YflT ATP-grasp_2 PF08442.10 CDJ54226.1 - 1.3 8.6 0.0 1.3 8.6 0.0 2.4 3 0 0 3 3 3 0 ATP-grasp domain WD40 PF00400.32 CDJ54227.1 - 5.6e-12 46.0 0.2 0.017 16.0 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat SR-25 PF10500.9 CDJ54228.1 - 0.095 12.3 6.8 0.15 11.7 6.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ54228.1 - 0.46 10.1 10.2 0.58 9.7 10.2 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ54228.1 - 2.1 8.3 10.5 2.5 8.0 10.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ54228.1 - 2.1 8.3 4.4 2.4 8.2 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Smg8_Smg9 PF10220.9 CDJ54228.1 - 2.7 6.2 8.4 3.2 6.0 8.4 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Roughex PF06020.11 CDJ54228.1 - 5.1 6.1 11.0 5.5 6.0 11.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Utp14 PF04615.13 CDJ54228.1 - 5.6 5.4 14.0 6.7 5.2 14.0 1.0 1 0 0 1 1 1 0 Utp14 protein Presenilin PF01080.17 CDJ54228.1 - 6.3 5.4 9.8 6.7 5.4 9.8 1.1 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.12 CDJ54228.1 - 7.5 5.1 8.1 8.3 4.9 8.1 1.0 1 0 0 1 1 1 0 Hamartin protein RR_TM4-6 PF06459.12 CDJ54228.1 - 8.3 6.1 7.5 9.9 5.9 7.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 C2 PF00168.30 CDJ54229.1 - 4.1e-05 23.8 0.0 4.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 C2 domain FAD_binding_2 PF00890.24 CDJ54230.1 - 1.4e-27 96.8 0.0 1.7e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain rve PF00665.26 CDJ54231.1 - 7.2e-09 35.9 0.0 1.3e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ54231.1 - 0.0078 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PKS_DE PF18369.1 CDJ54231.1 - 0.44 11.2 3.3 32 5.2 1.7 3.1 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain Cpn60_TCP1 PF00118.24 CDJ54232.1 - 7.2e-37 127.2 5.6 7.2e-36 123.8 5.6 2.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family HEPPP_synt_1 PF07307.11 CDJ54232.1 - 0.011 15.4 0.8 0.017 14.8 0.8 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 ATG_C PF09333.11 CDJ54232.1 - 0.34 11.3 4.1 4.3 7.8 1.5 2.3 1 1 1 2 2 2 0 Autophagy-related protein C terminal domain HCO3_cotransp PF00955.21 CDJ54233.1 - 0.0013 17.7 9.0 0.0016 17.4 9.0 1.4 1 0 0 1 1 1 1 HCO3- transporter family RR_TM4-6 PF06459.12 CDJ54233.1 - 0.0033 17.3 25.5 0.0033 17.3 25.5 2.2 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 CDJ54233.1 - 0.015 13.7 47.1 0.017 13.4 47.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SARAF PF06682.12 CDJ54233.1 - 0.14 11.7 28.7 0.26 10.9 8.6 2.1 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis MAP7 PF05672.11 CDJ54233.1 - 0.52 10.0 62.4 0.22 11.2 50.9 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Raftlin PF15250.6 CDJ54233.1 - 0.75 8.5 27.9 1.1 8.0 27.9 1.3 1 0 0 1 1 1 0 Raftlin GAGA_bind PF06217.12 CDJ54233.1 - 3.3 7.9 29.6 0.095 13.0 19.9 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family DUF2417 PF10329.9 CDJ54233.1 - 4.8 6.5 8.1 5.8 6.3 4.1 2.2 1 1 0 2 2 2 0 Region of unknown function (DUF2417) Peptidase_M56 PF05569.11 CDJ54233.1 - 7.5 5.6 15.9 0.71 9.0 9.9 2.0 1 1 1 2 2 2 0 BlaR1 peptidase M56 Ribosomal_60s PF00428.19 CDJ54233.1 - 7.7 7.2 21.2 14 6.4 14.8 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein CK2S PF15011.6 CDJ54234.1 - 0.0077 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Casein Kinase 2 substrate DNA_pol_A PF00476.20 CDJ54234.1 - 0.018 14.1 0.0 0.84 8.6 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase family A Nrap_D4 PF17405.2 CDJ54234.1 - 0.097 12.0 0.2 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 Nrap protein nucleotidyltransferase domain 4 DUF3138 PF11336.8 CDJ54234.1 - 0.29 9.7 2.9 0.33 9.5 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RskA PF10099.9 CDJ54234.1 - 0.31 11.3 15.7 0.22 11.8 12.4 1.9 2 0 0 2 2 2 0 Anti-sigma-K factor rskA PIEZO PF15917.5 CDJ54235.1 - 0.032 13.7 11.3 0.034 13.6 11.3 1.1 1 0 0 1 1 1 0 Piezo Peptidase_S49_N PF08496.10 CDJ54235.1 - 0.16 12.1 8.3 0.18 11.8 8.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4746 PF15928.5 CDJ54235.1 - 0.2 11.0 5.0 0.21 11.0 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Exonuc_VII_L PF02601.15 CDJ54235.1 - 0.33 10.5 15.2 0.37 10.3 15.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit CPSF100_C PF13299.6 CDJ54235.1 - 0.44 10.7 6.9 0.54 10.4 6.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NEMP PF10225.9 CDJ54235.1 - 0.5 10.0 5.1 0.55 9.9 5.1 1.1 1 0 0 1 1 1 0 NEMP family CLN3 PF02487.17 CDJ54235.1 - 0.6 9.1 5.0 0.58 9.2 5.0 1.1 1 0 0 1 1 1 0 CLN3 protein Roughex PF06020.11 CDJ54235.1 - 0.62 9.1 9.6 0.83 8.7 9.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein HCO3_cotransp PF00955.21 CDJ54235.1 - 0.77 8.5 2.9 0.91 8.3 2.9 1.0 1 0 0 1 1 1 0 HCO3- transporter family eIF-3_zeta PF05091.12 CDJ54235.1 - 1.1 8.2 15.4 1.1 8.1 15.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 CDJ54235.1 - 1.2 9.2 14.7 1.7 8.7 14.7 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Activator_LAG-3 PF11498.8 CDJ54235.1 - 1.2 8.1 44.3 1.3 7.9 44.3 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.10 CDJ54235.1 - 1.2 7.7 28.6 1.2 7.7 28.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FPN1 PF06963.12 CDJ54235.1 - 1.2 7.6 3.7 1.4 7.3 3.7 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Cons_hypoth95 PF03602.15 CDJ54235.1 - 1.4 8.5 6.0 1.9 8.1 6.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 HemX PF04375.14 CDJ54235.1 - 2 7.7 29.2 2.3 7.4 29.2 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Cyto_heme_lyase PF01265.17 CDJ54235.1 - 2 7.9 12.5 2.4 7.7 12.5 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase UPF0560 PF10577.9 CDJ54235.1 - 2.2 6.7 17.9 2.4 6.5 17.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MMR1 PF08505.10 CDJ54235.1 - 2.3 8.4 18.2 2.6 8.3 18.2 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DDHD PF02862.17 CDJ54235.1 - 2.6 8.1 10.7 2.7 8.1 10.7 1.1 1 0 0 1 1 1 0 DDHD domain Hydin_ADK PF17213.3 CDJ54235.1 - 2.7 8.2 13.9 3 8.1 13.9 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MAJIN PF15077.6 CDJ54235.1 - 3 7.6 9.9 3.5 7.4 9.9 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Suf PF05843.14 CDJ54235.1 - 3.4 7.6 17.0 4.4 7.2 17.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Rrn6 PF10214.9 CDJ54235.1 - 4.2 5.7 22.1 4.8 5.5 22.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ctr PF04145.15 CDJ54235.1 - 4.4 7.9 7.2 5.2 7.7 7.2 1.3 1 0 0 1 1 1 0 Ctr copper transporter family SLC12 PF03522.15 CDJ54235.1 - 4.4 6.2 12.0 4.4 6.2 12.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 TFIIA PF03153.13 CDJ54235.1 - 5 7.0 35.9 5.5 6.9 35.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2828 PF11443.8 CDJ54235.1 - 5.6 4.9 12.4 6.5 4.7 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Pex14_N PF04695.13 CDJ54235.1 - 6 7.5 23.1 6.8 7.3 23.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YjbH PF06082.11 CDJ54235.1 - 6.1 5.5 10.4 6.7 5.4 10.4 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH ALMT PF11744.8 CDJ54235.1 - 6.3 5.5 8.8 6.7 5.4 8.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3824 PF12868.7 CDJ54235.1 - 6.4 7.4 17.7 11 6.7 17.7 1.4 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) R_equi_Vir PF05526.11 CDJ54235.1 - 7.8 6.3 8.0 9.8 6.0 8.0 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein GREB1 PF15782.5 CDJ54235.1 - 7.9 3.5 16.5 8 3.4 16.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Connexin PF00029.19 CDJ54235.1 - 8.4 6.1 8.9 9.8 5.9 8.9 1.1 1 0 0 1 1 1 0 Connexin Peptidase_U57 PF05582.12 CDJ54235.1 - 8.7 5.5 10.9 9.5 5.4 10.9 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Sec62 PF03839.16 CDJ54235.1 - 9 5.7 8.1 11 5.5 8.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 MAT1 PF06391.13 CDJ54236.1 - 0.19 11.5 22.5 0.22 11.4 22.5 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Pal1 PF08316.11 CDJ54236.1 - 2.1 9.1 7.3 2.3 9.0 7.3 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein SpoIIP PF07454.11 CDJ54236.1 - 2.9 7.3 17.6 2.8 7.3 17.6 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4407 PF14362.6 CDJ54236.1 - 3.2 7.0 20.8 3.8 6.8 20.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Velvet PF11754.8 CDJ54236.1 - 4.6 7.1 19.6 5.2 6.9 19.6 1.0 1 0 0 1 1 1 0 Velvet factor EIIBC-GUT_N PF03612.14 CDJ54236.1 - 4.9 6.8 14.1 5.9 6.6 14.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Cellulose_synt PF03552.14 CDJ54236.1 - 5.4 5.4 6.8 5.7 5.3 6.8 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF3464 PF11947.8 CDJ54236.1 - 6.8 6.4 17.6 7.8 6.2 17.6 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Connexin PF00029.19 CDJ54236.1 - 6.8 6.4 14.1 7.1 6.3 14.1 1.0 1 0 0 1 1 1 0 Connexin Tim54 PF11711.8 CDJ54236.1 - 7.9 5.2 15.4 8.2 5.1 15.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CLN3 PF02487.17 CDJ54236.1 - 8.3 5.3 14.6 8.9 5.2 14.6 1.0 1 0 0 1 1 1 0 CLN3 protein CPSF100_C PF13299.6 CDJ54236.1 - 8.8 6.5 14.1 10 6.3 14.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AAA_11 PF13086.6 CDJ54237.1 - 1.7 8.3 8.0 1.9 8.2 8.0 1.3 1 0 0 1 1 1 0 AAA domain NPR3 PF03666.13 CDJ54237.1 - 1.8 7.3 18.0 2.3 6.9 18.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 CDJ54237.1 - 2.1 8.1 13.2 2.6 7.8 13.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 CDJ54237.1 - 2.7 6.0 8.1 2.9 5.9 8.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CDJ54237.1 - 7.9 5.1 14.9 10 4.8 14.9 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ54238.1 - 0.081 12.9 46.5 0.095 12.7 46.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ54238.1 - 0.082 11.6 36.0 0.1 11.3 36.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Connexin PF00029.19 CDJ54238.1 - 0.086 12.6 12.6 0.12 12.2 12.6 1.3 1 0 0 1 1 1 0 Connexin ADP_ribosyl_GH PF03747.14 CDJ54238.1 - 0.14 11.9 7.8 0.17 11.6 7.8 1.0 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase eIF-3_zeta PF05091.12 CDJ54238.1 - 0.16 10.9 22.2 0.17 10.8 22.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RskA PF10099.9 CDJ54238.1 - 0.21 11.9 19.3 0.43 10.8 19.2 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA PMSI1 PF15322.6 CDJ54238.1 - 0.21 11.0 16.2 0.24 10.8 16.2 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative BAF1_ABF1 PF04684.13 CDJ54238.1 - 0.25 10.4 23.6 0.31 10.0 23.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF5427 PF10310.9 CDJ54238.1 - 0.44 9.5 23.8 0.45 9.4 23.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) V_ATPase_I PF01496.19 CDJ54238.1 - 0.44 8.4 17.9 0.49 8.2 17.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CDJ54238.1 - 0.53 9.0 25.4 0.53 9.0 25.4 1.2 1 0 0 1 1 1 0 Presenilin Ribosomal_60s PF00428.19 CDJ54238.1 - 0.64 10.6 11.2 0.34 11.5 9.1 1.6 2 0 0 2 2 1 0 60s Acidic ribosomal protein ASC PF00858.24 CDJ54238.1 - 0.66 8.9 6.7 0.73 8.7 6.7 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Lin-8 PF03353.15 CDJ54238.1 - 0.75 9.3 25.4 0.89 9.1 25.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hydin_ADK PF17213.3 CDJ54238.1 - 1 9.6 22.5 1.3 9.3 22.5 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Suf PF05843.14 CDJ54238.1 - 1.5 8.8 26.0 2.1 8.3 26.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PIN_12 PF16289.5 CDJ54238.1 - 1.5 9.3 4.3 1.7 9.1 4.3 1.3 1 0 0 1 1 1 0 PIN domain FAM60A PF15396.6 CDJ54238.1 - 2 8.4 17.8 2.4 8.1 17.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A HAUS6_N PF14661.6 CDJ54238.1 - 2.4 7.7 22.2 2.5 7.6 22.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SLC12 PF03522.15 CDJ54238.1 - 2.4 7.1 22.3 2.5 7.0 22.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PIEZO PF15917.5 CDJ54238.1 - 2.7 7.4 23.1 3.4 7.1 23.1 1.2 1 0 0 1 1 1 0 Piezo CDC45 PF02724.14 CDJ54238.1 - 2.9 6.1 17.4 3 6.0 17.4 1.0 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.6 CDJ54238.1 - 3.1 6.1 7.7 3.3 6.0 7.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4569 PF15133.6 CDJ54238.1 - 3.1 7.4 20.9 3.8 7.1 20.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) AUX_IAA PF02309.16 CDJ54238.1 - 3.3 7.5 17.8 3.9 7.3 17.8 1.2 1 0 0 1 1 1 0 AUX/IAA family SelP_N PF04592.14 CDJ54238.1 - 3.5 7.0 34.2 4.9 6.5 34.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FPN1 PF06963.12 CDJ54238.1 - 4 5.9 7.1 5 5.6 7.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) RR_TM4-6 PF06459.12 CDJ54238.1 - 4.1 7.2 23.4 6 6.6 23.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CDJ54238.1 - 4.3 7.4 18.9 6 7.0 18.9 1.3 1 0 0 1 1 1 0 DDHD domain MMR1 PF08505.10 CDJ54238.1 - 4.4 7.5 27.3 5.2 7.3 27.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Endostatin PF06482.11 CDJ54238.1 - 4.4 6.7 21.3 4.8 6.5 21.3 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4175 PF13779.6 CDJ54238.1 - 4.9 4.9 42.1 4.8 5.0 42.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) HemX PF04375.14 CDJ54238.1 - 5.3 6.2 38.2 6 6.1 38.2 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CLN3 PF02487.17 CDJ54238.1 - 6.4 5.7 13.4 7.8 5.4 13.4 1.3 1 0 0 1 1 1 0 CLN3 protein Membralin PF09746.9 CDJ54238.1 - 6.5 5.7 13.1 6.4 5.7 13.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein Asp-B-Hydro_N PF05279.11 CDJ54238.1 - 6.8 6.7 15.1 7.5 6.6 15.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDK5_activator PF03261.15 CDJ54238.1 - 6.9 6.1 18.1 7 6.1 18.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein OmpH PF03938.14 CDJ54238.1 - 7 7.0 38.3 9.6 6.5 38.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ureide_permease PF07168.11 CDJ54238.1 - 7.2 5.2 8.9 8.9 4.9 8.9 1.2 1 0 0 1 1 1 0 Ureide permease Paramyxo_ncap PF00973.19 CDJ54238.1 - 7.3 5.4 15.2 7.4 5.4 15.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CSG2 PF16965.5 CDJ54238.1 - 7.6 5.4 9.4 8.8 5.1 9.4 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DDRGK PF09756.9 CDJ54238.1 - 7.8 6.0 28.3 11 5.6 28.3 1.3 1 0 0 1 1 1 0 DDRGK domain MDM10 PF12519.8 CDJ54238.1 - 8.2 5.2 21.1 10 4.9 21.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF572 PF04502.13 CDJ54238.1 - 8.4 5.9 20.6 9.8 5.7 20.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.9 CDJ54238.1 - 8.4 4.8 22.2 10 4.6 22.2 1.0 1 0 0 1 1 1 0 Macoilin family DUF4734 PF15881.5 CDJ54239.1 - 0.0011 19.1 5.3 0.18 12.0 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4734) Methyltransf_34 PF11312.8 CDJ54239.1 - 0.043 13.1 1.2 0.047 12.9 1.2 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase DUF5308 PF17233.2 CDJ54239.1 - 3 8.0 7.2 0.33 11.1 0.7 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5308) RskA PF10099.9 CDJ54240.1 - 0.0051 17.1 5.2 0.039 14.3 2.5 2.3 2 0 0 2 2 2 1 Anti-sigma-K factor rskA AF-4 PF05110.13 CDJ54240.1 - 0.017 13.2 11.9 0.021 13.0 11.9 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein K_channel_TID PF07941.11 CDJ54240.1 - 0.019 15.4 6.0 0.019 15.4 6.0 3.1 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Apt1 PF10351.9 CDJ54240.1 - 0.11 11.4 2.3 0.11 11.3 2.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pap_E4 PF02711.14 CDJ54240.1 - 0.15 13.0 3.7 0.53 11.3 3.7 2.0 1 1 0 1 1 1 0 E4 protein Lin-8 PF03353.15 CDJ54240.1 - 0.18 11.3 2.2 0.27 10.8 2.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Herpes_pp85 PF04637.12 CDJ54240.1 - 2.3 6.5 13.6 4.5 5.6 13.6 1.5 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) G_path_suppress PF15991.5 CDJ54240.1 - 2.8 8.0 11.2 5.9 6.9 11.2 1.4 1 1 0 1 1 1 0 G-protein pathway suppressor TraT PF05818.12 CDJ54241.1 - 0.0047 16.6 14.6 0.006 16.3 14.6 1.1 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein TFIIA PF03153.13 CDJ54241.1 - 0.05 13.6 35.0 0.052 13.5 35.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM199X PF15814.5 CDJ54241.1 - 0.27 10.2 15.1 0.32 10.0 15.1 1.0 1 0 0 1 1 1 0 Protein family FAM199X TERB2 PF15101.6 CDJ54241.1 - 0.72 9.9 14.9 0.91 9.5 14.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Peptidase_C37 PF05416.12 CDJ54241.1 - 0.76 8.2 11.6 0.91 8.0 11.6 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase eIF-3_zeta PF05091.12 CDJ54241.1 - 1.3 7.9 19.3 1.4 7.8 19.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.6 CDJ54241.1 - 1.5 7.1 2.9 1.7 6.9 2.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RskA PF10099.9 CDJ54241.1 - 1.6 9.0 39.8 3.5 7.9 39.8 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DDHD PF02862.17 CDJ54241.1 - 1.6 8.8 11.4 2.1 8.4 11.4 1.2 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.15 CDJ54241.1 - 2.8 6.7 7.6 3.1 6.6 7.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) BAF1_ABF1 PF04684.13 CDJ54241.1 - 2.9 6.9 18.9 4 6.4 18.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Draxin PF15550.6 CDJ54241.1 - 3 7.6 13.9 3.3 7.5 13.9 1.0 1 0 0 1 1 1 0 Draxin Neur_chan_memb PF02932.16 CDJ54241.1 - 3.1 7.8 8.5 3.8 7.5 8.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 CDJ54241.1 - 3.8 7.4 6.2 4.8 7.1 6.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein 2HCT PF03390.15 CDJ54241.1 - 4.2 5.9 7.6 4.9 5.6 7.6 1.0 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family RR_TM4-6 PF06459.12 CDJ54241.1 - 4.3 7.1 15.4 5 6.9 15.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 R_equi_Vir PF05526.11 CDJ54241.1 - 4.3 7.2 14.5 6.2 6.7 14.5 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Prismane PF03063.20 CDJ54241.1 - 6.3 5.4 12.0 7.5 5.1 12.0 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family FAM60A PF15396.6 CDJ54241.1 - 7.7 6.5 10.9 9.2 6.2 10.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Connexin PF00029.19 CDJ54241.1 - 8.7 6.0 10.4 11 5.7 10.4 1.1 1 0 0 1 1 1 0 Connexin IHABP4_N PF16174.5 CDJ54241.1 - 9.2 6.8 27.5 13 6.3 27.5 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal IRK PF01007.20 CDJ54242.1 - 4.5e-08 33.0 0.1 7.6e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 CDJ54242.1 - 1.5e-06 27.9 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans PF00520.31 CDJ54242.1 - 0.0002 20.7 3.5 0.0003 20.1 3.5 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CDJ54242.1 - 0.0066 16.4 5.0 0.013 15.5 5.0 1.5 1 0 0 1 1 1 1 Ion channel Dpy-30 PF05186.13 CDJ54243.1 - 4.2e-12 45.6 0.8 4.2e-12 45.6 0.8 1.8 2 0 0 2 2 2 1 Dpy-30 motif TMEM213 PF15192.6 CDJ54246.1 - 0.1 12.6 0.3 0.1 12.6 0.3 1.7 2 0 0 2 2 2 0 TMEM213 family DUF5539 PF17693.1 CDJ54251.1 - 0.04 13.6 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5539) RskA PF10099.9 CDJ54252.1 - 0.031 14.6 29.5 0.063 13.6 5.4 2.8 1 1 2 3 3 3 0 Anti-sigma-K factor rskA Retrotrans_gag PF03732.17 CDJ54253.1 - 0.041 14.1 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein DUF1570 PF07607.11 CDJ54253.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) SAP130_C PF16014.5 CDJ54256.1 - 0.28 10.2 11.3 0.27 10.3 11.3 1.0 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Spt20 PF12090.8 CDJ54256.1 - 0.43 10.2 4.0 0.48 10.0 4.0 1.2 1 0 0 1 1 1 0 Spt20 family BAT2_N PF07001.11 CDJ54256.1 - 0.54 10.7 12.6 0.63 10.5 12.6 1.1 1 0 0 1 1 1 0 BAT2 N-terminus tRNA_synt_1c_R2 PF04557.15 CDJ54256.1 - 1.3 10.0 8.1 1.5 9.8 0.2 2.1 1 1 1 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 MFS_1 PF07690.16 CDJ54258.1 - 4.7e-09 35.6 26.0 4.7e-09 35.6 26.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily ERGIC_N PF13850.6 CDJ54258.1 - 0.022 15.1 1.2 0.12 12.8 0.4 2.5 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) GBP PF02263.19 CDJ54259.1 - 1.2e-18 67.4 0.0 2.6e-17 62.9 0.0 2.5 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 CDJ54259.1 - 3.6e-10 39.7 20.4 1.1e-09 38.1 20.4 1.7 1 1 0 1 1 1 1 Guanylate-binding protein, C-terminal domain PmbA_TldD PF01523.16 CDJ54259.1 - 0.056 13.3 1.2 0.24 11.2 0.0 2.4 2 0 0 2 2 2 0 Putative modulator of DNA gyrase Dynamin_N PF00350.23 CDJ54259.1 - 2.4 8.2 5.3 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Dynamin family ABC_membrane PF00664.23 CDJ54261.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region HSCB_C PF07743.13 CDJ54262.1 - 2.7 8.6 11.0 0.79 10.3 1.7 2.8 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain RskA PF10099.9 CDJ54265.1 - 0.0011 19.3 22.7 0.0011 19.3 22.7 2.6 1 1 0 2 2 1 1 Anti-sigma-K factor rskA Exonuc_VII_L PF02601.15 CDJ54265.1 - 0.0064 16.1 27.0 0.0091 15.6 27.0 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF4834 PF16118.5 CDJ54265.1 - 0.035 15.0 1.6 0.035 15.0 1.6 3.2 2 1 1 3 3 1 0 Domain of unknown function (DUF4834) Ndc1_Nup PF09531.10 CDJ54265.1 - 0.066 11.9 25.6 0.083 11.6 25.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ArsP_2 PF11449.8 CDJ54265.1 - 0.11 11.7 8.2 0.19 10.9 8.2 1.3 1 1 0 1 1 1 0 Putative, 10TM heavy-metal exporter SLC12 PF03522.15 CDJ54265.1 - 0.3 10.1 28.0 0.42 9.6 28.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RPN2_C PF18004.1 CDJ54265.1 - 0.36 10.7 20.4 3.8 7.4 0.1 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Hid1 PF12722.7 CDJ54265.1 - 1.1 7.3 26.7 1.5 6.8 26.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YL1 PF05764.13 CDJ54265.1 - 1.4 8.9 39.5 2 8.5 39.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Band_3_cyto PF07565.13 CDJ54265.1 - 2.1 8.1 30.0 1.1 9.0 19.1 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Glyco_hydro_9 PF00759.19 CDJ54265.1 - 2.1 7.7 18.4 3.1 7.1 18.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Silic_transp PF03842.13 CDJ54265.1 - 2.8 6.1 5.8 5.6 5.1 5.8 1.5 1 1 0 1 1 1 0 Silicon transporter LMBR1 PF04791.16 CDJ54265.1 - 3.9 6.3 15.7 4.9 5.9 15.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1387 PF07139.11 CDJ54265.1 - 4.1 7.1 30.9 5.1 6.7 30.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Pkinase PF00069.25 CDJ54265.1 - 6.2 6.1 12.6 0.44 9.9 0.2 2.1 2 0 0 2 2 2 0 Protein kinase domain MMADHC PF10229.9 CDJ54265.1 - 8.5 6.0 24.3 0.66 9.7 16.0 2.0 2 0 0 2 2 2 0 Methylmalonic aciduria and homocystinuria type D protein Mago-bind PF09282.10 CDJ54266.1 - 0.26 11.2 1.1 19 5.2 0.4 2.4 2 0 0 2 2 2 0 Mago binding HisKA_3 PF07730.13 CDJ54267.1 - 0.0073 16.8 0.2 0.016 15.7 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase DNA_pol_B PF00136.21 CDJ54269.1 - 1.5e-67 228.3 0.0 3.5e-66 223.8 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B zf-C4pol PF14260.6 CDJ54269.1 - 2.4e-06 27.9 4.8 2.4e-06 27.9 4.8 3.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Phage_F PF02305.17 CDJ54270.1 - 0.026 13.3 7.7 0.3 9.8 0.5 3.8 3 1 2 5 5 5 0 Capsid protein (F protein) Peptidase_C2 PF00648.21 CDJ54271.1 - 1.1e-19 70.6 0.0 6.6e-11 41.8 0.0 3.3 2 1 0 2 2 2 2 Calpain family cysteine protease Pex14_N PF04695.13 CDJ54271.1 - 7.2 7.2 21.0 1.8 9.2 2.3 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5327 PF17261.2 CDJ54273.1 - 0.89 10.3 18.7 1 10.2 18.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Coilin_N PF15862.5 CDJ54273.1 - 1.1 9.1 16.3 1.3 8.8 16.3 1.3 1 0 0 1 1 1 0 Coilin N-terminus SpoIIP PF07454.11 CDJ54273.1 - 2.2 7.7 16.2 2.1 7.7 16.2 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF3408 PF11888.8 CDJ54273.1 - 2.3 8.4 14.3 2.3 8.3 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SID-1_RNA_chan PF13965.6 CDJ54273.1 - 2.4 6.4 4.2 2.5 6.4 4.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.10 CDJ54273.1 - 2.8 8.0 12.1 3 7.9 12.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ureide_permease PF07168.11 CDJ54273.1 - 2.8 6.6 7.8 3.3 6.4 7.8 1.1 1 0 0 1 1 1 0 Ureide permease Pex14_N PF04695.13 CDJ54273.1 - 3.1 8.5 27.1 4 8.1 27.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ54273.1 - 3.2 7.4 11.0 3.1 7.5 11.0 1.0 1 0 0 1 1 1 0 Connexin Activator_LAG-3 PF11498.8 CDJ54273.1 - 3.3 6.6 36.1 3.3 6.6 36.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AIF_C PF14721.6 CDJ54273.1 - 3.5 8.0 12.6 4.2 7.7 12.6 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term R_equi_Vir PF05526.11 CDJ54273.1 - 4.1 7.2 12.9 4.6 7.1 12.9 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SLC12 PF03522.15 CDJ54273.1 - 4.5 6.2 12.4 4.3 6.2 12.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_U57 PF05582.12 CDJ54273.1 - 4.6 6.4 10.4 4.7 6.4 10.4 1.0 1 0 0 1 1 1 0 YabG peptidase U57 BAF1_ABF1 PF04684.13 CDJ54273.1 - 4.9 6.1 17.7 5.6 5.9 17.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TERB2 PF15101.6 CDJ54273.1 - 4.9 7.2 18.7 4.9 7.2 18.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Rxt3 PF08642.10 CDJ54273.1 - 5.3 7.8 7.7 6.6 7.5 7.7 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 eIF-3_zeta PF05091.12 CDJ54273.1 - 5.3 5.9 18.8 5.1 6.0 18.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1980 PF09323.10 CDJ54273.1 - 6.3 6.7 13.8 7.2 6.5 13.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) EIIBC-GUT_N PF03612.14 CDJ54273.1 - 7.1 6.3 14.0 7.9 6.2 14.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RR_TM4-6 PF06459.12 CDJ54273.1 - 8.4 6.1 19.0 8.5 6.1 19.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ctr PF04145.15 CDJ54273.1 - 9.1 6.9 7.7 10 6.7 7.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family EOS1 PF12326.8 CDJ54273.1 - 9.3 6.1 7.2 10 6.0 7.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein Atg14 PF10186.9 CDJ54275.1 - 0.002 17.3 9.7 0.002 17.3 9.7 3.1 3 0 0 3 3 3 2 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 CDJ54275.1 - 0.37 9.6 27.8 0.14 11.0 15.0 2.9 2 1 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 CDJ54275.1 - 5.3 7.1 42.3 0.17 11.9 26.4 3.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Helicase_C PF00271.31 CDJ54276.1 - 9.8e-07 29.1 0.1 9.8e-07 29.1 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ54276.1 - 0.0063 16.3 0.3 0.016 15.0 0.3 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 CDJ54276.1 - 0.023 15.1 0.8 0.12 12.7 0.2 2.6 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 CDJ54276.1 - 0.054 12.6 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 CDJ54276.1 - 0.13 12.6 0.2 0.58 10.5 0.2 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ54276.1 - 0.18 12.3 0.0 0.83 10.2 0.0 2.2 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 CDJ54276.1 - 0.26 10.9 0.9 0.79 9.3 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 CDJ54276.1 - 0.81 10.2 5.2 0.98 9.9 0.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ54276.1 - 1.5 8.5 5.3 1.2 8.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain HA2 PF04408.23 CDJ54276.1 - 2.1 8.6 4.7 0.91 9.8 0.0 2.6 2 0 0 2 2 2 0 Helicase associated domain (HA2) ABC1 PF03109.16 CDJ54277.1 - 3.9e-15 56.1 0.0 4.9e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 ABC1 family Titin_Ig-rpts PF06582.12 CDJ54277.1 - 0.13 12.2 0.2 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 Titin repeat Trp_oprn_chp PF09534.10 CDJ54278.1 - 0.0021 17.9 1.5 0.0024 17.7 1.5 1.0 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RskA PF10099.9 CDJ54278.1 - 0.0043 17.4 19.9 0.0053 17.1 19.9 1.0 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF4757 PF15949.5 CDJ54278.1 - 0.0087 16.5 8.9 0.0098 16.4 8.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4757) DUF2854 PF11016.8 CDJ54278.1 - 0.15 12.0 4.3 0.11 12.4 3.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2854) YceD PF02620.17 CDJ54278.1 - 0.24 11.5 3.4 0.29 11.3 3.3 1.3 1 1 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD THOC2_N PF16134.5 CDJ54278.1 - 0.26 9.9 8.8 0.28 9.8 8.8 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus SMYLE_N PF18615.1 CDJ54278.1 - 0.27 10.7 6.2 0.31 10.5 6.2 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain OATP PF03137.20 CDJ54278.1 - 0.52 8.5 1.5 0.53 8.5 1.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SARAF PF06682.12 CDJ54278.1 - 1 9.0 12.7 1.1 8.9 12.7 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TFIIA PF03153.13 CDJ54278.1 - 1.2 9.1 34.4 1.6 8.7 34.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.15 CDJ54278.1 - 2 7.2 4.0 2.1 7.2 4.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4770 PF15994.5 CDJ54278.1 - 2.9 8.1 11.5 0.92 9.7 8.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Spore_coat_CotO PF14153.6 CDJ54278.1 - 6.4 6.7 19.2 8.9 6.2 19.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Med15 PF09606.10 CDJ54278.1 - 6.4 5.3 29.0 7.5 5.1 29.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PepSY_2 PF13670.6 CDJ54278.1 - 7.8 6.6 12.8 0.38 10.8 7.7 1.5 2 0 0 2 2 1 0 Peptidase propeptide and YPEB domain UPF0560 PF10577.9 CDJ54278.1 - 8.8 4.7 16.1 12 4.3 16.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Dehydrin PF00257.19 CDJ54284.1 - 0.17 12.4 1.5 10 6.6 0.0 2.2 2 0 0 2 2 2 0 Dehydrin NAD_binding_8 PF13450.6 CDJ54285.1 - 0.11 12.7 0.1 6.2 7.1 0.0 2.1 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain HycI PF01750.18 CDJ54285.1 - 0.16 11.8 1.0 2.6 7.9 0.0 2.0 1 1 1 2 2 2 0 Hydrogenase maturation protease DUF2812 PF11193.8 CDJ54285.1 - 0.2 11.9 0.3 22 5.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2812) NCBP3 PF10309.9 CDJ54285.1 - 3.4 7.6 6.0 16 5.4 1.5 2.7 2 1 0 2 2 2 0 Nuclear cap-binding protein subunit 3 DUF2374 PF09574.10 CDJ54286.1 - 0.0026 17.5 3.0 0.0039 17.0 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (Duf2374) Tom37_C PF11801.8 CDJ54287.1 - 0.01 15.8 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF937 PF06078.11 CDJ54289.1 - 0.044 14.4 0.0 0.068 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) DUF350 PF03994.14 CDJ54291.1 - 0.0082 16.3 1.7 0.56 10.4 0.0 3.2 3 1 0 3 3 3 1 Domain of Unknown Function (DUF350) DUF2374 PF09574.10 CDJ54291.1 - 0.12 12.2 0.5 7.7 6.4 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Ribosomal_60s PF00428.19 CDJ54294.1 - 0.091 13.4 36.1 0.052 14.1 9.6 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein Pex19 PF04614.12 CDJ54294.1 - 4 7.1 7.0 34 4.1 7.1 2.0 1 1 0 1 1 1 0 Pex19 protein family SCAB-ABD PF16711.5 CDJ54295.1 - 0.084 12.8 0.3 0.42 10.5 0.0 2.4 2 0 0 2 2 2 0 Actin-binding domain of plant-specific actin-binding protein PI3K_P85_iSH2 PF16454.5 CDJ54295.1 - 0.22 11.1 2.1 6.4 6.3 0.3 2.5 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc24 PF08286.11 CDJ54295.1 - 1.9 8.8 5.9 3.6 7.9 0.9 3.0 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 CK2S PF15011.6 CDJ54295.1 - 6 6.7 8.5 6.4 6.6 0.0 3.8 5 0 0 5 5 5 0 Casein Kinase 2 substrate DUF3827 PF12877.7 CDJ54296.1 - 1.3 7.3 8.2 1.9 6.8 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CDC27 PF09507.10 CDJ54297.1 - 0.064 12.6 3.1 0.12 11.8 3.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Helicase_C_2 PF13307.6 CDJ54298.1 - 9.1e-36 123.6 3.3 8.1e-34 117.3 0.1 2.9 3 0 0 3 3 3 2 Helicase C-terminal domain DEAD_2 PF06733.15 CDJ54298.1 - 5.6e-20 71.7 0.0 1.2e-19 70.6 0.0 1.6 2 0 0 2 2 2 1 DEAD_2 DUF2415 PF10313.9 CDJ54301.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) AP2 PF00847.20 CDJ54302.1 - 2.9e-06 27.4 4.1 0.0055 16.9 0.8 2.4 2 0 0 2 2 2 2 AP2 domain Clp_N PF02861.20 CDJ54302.1 - 0.093 12.9 0.7 0.58 10.3 1.0 2.2 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component AP2 PF00847.20 CDJ54303.1 - 1.9e-20 72.8 4.0 2e-10 40.8 0.2 3.3 3 0 0 3 3 3 2 AP2 domain ACDC PF14733.6 CDJ54303.1 - 4.6e-17 62.1 0.4 9.4e-17 61.1 0.4 1.5 1 0 0 1 1 1 1 AP2-coincident C-terminal Hydrolase_4 PF12146.8 CDJ54306.1 - 3.5e-20 72.3 0.4 4.5e-08 32.7 0.0 3.4 3 1 0 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ54306.1 - 0.0085 16.7 13.2 0.086 13.4 13.2 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family rve PF00665.26 CDJ54307.1 - 1.9e-13 50.6 0.1 6.6e-13 48.9 0.0 2.0 3 0 0 3 3 3 1 Integrase core domain RT_RNaseH PF17917.1 CDJ54307.1 - 3.8e-08 33.6 0.0 7.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ54307.1 - 0.00066 19.7 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 CDJ54308.1 - 5e-09 35.9 0.0 8.2e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Vitelline_membr PF10542.9 CDJ54308.1 - 0.3 11.0 4.7 0.83 9.6 4.7 1.8 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria_brunetti-EBH001/GCA_000499725.1_EBH001_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria_brunetti-EBH001/GCA_000499725.1_EBH001_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria_brunetti-EBH001/GCA_000499725.1_EBH001_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria_brunetti-EBH001/GCA_000499725.1_EBH001_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 01:37:04 2019 # [ok]